GeneModel BLAST Result against human

BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA002171-TA|BGIBMGA002171-PA|IPR001128|Cytochrome P450
         (389 letters)

Database: human 
           224,733 sequences; 73,234,838 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

M14096-1|AAA35744.1|  503|Homo sapiens protein ( Human cytochrom...   165   2e-40
J04449-1|AAA35747.1|  502|Homo sapiens cytochrome P450 nifedipin...   165   2e-40
M18907-1|AAA35745.1|  503|Homo sapiens protein ( Human P450 mRNA...   163   9e-40
DQ924960-1|ABI96208.1|  503|Homo sapiens cytochrome P450 family ...   163   9e-40
DQ005611-1|AAY16980.1|  503|Homo sapiens cytochrome P450, family...   163   9e-40
BC101631-1|AAI01632.1|  503|Homo sapiens cytochrome P450, subfam...   163   9e-40
BC069418-1|AAH69418.1|  503|Homo sapiens cytochrome P450, family...   163   9e-40
AJ563377-1|CAD91345.1|  353|Homo sapiens cytochrome P450 protein.     163   9e-40
AJ563376-2|CAD91645.1|  430|Homo sapiens cytochrome P450 protein.     163   9e-40
AJ563375-1|CAD91343.1|  503|Homo sapiens cytochrome P450 protein.     163   9e-40
AF280107-2|AAG32290.1|  503|Homo sapiens cytochrome P450 polypep...   163   9e-40
AF209389-1|AAF21034.1|  503|Homo sapiens cytochrome P450 IIIA4 p...   163   9e-40
X12387-1|CAA30944.1|  503|Homo sapiens protein ( Human mRNA for ...   163   1e-39
M13785-1|AAA35742.1|  504|Homo sapiens protein ( Human liver glu...   163   1e-39
D00003-1|BAA00001.1|  504|Homo sapiens cytochrome P-450 protein.      163   1e-39
AF182273-1|AAF13598.1|  503|Homo sapiens cytochrome P450-3A4 pro...   161   4e-39
D00408-1|BAA00310.1|  503|Homo sapiens cytochrome P-450 HFLa pro...   155   3e-37
BC067436-1|AAH67436.1|  503|Homo sapiens cytochrome P450, family...   155   3e-37
AF315325-1|AAG48618.1|  535|Homo sapiens cytochrome P450 variant...   155   3e-37
AF280107-3|AAG32289.1|  503|Homo sapiens cytochrome P450 polypep...   155   3e-37
J04813-1|AAA02993.1|  502|Homo sapiens cytochrome P450 PCN3 prot...   155   3e-37
BC033862-1|AAH33862.1|  502|Homo sapiens cytochrome P450, family...   155   3e-37
AK223008-1|BAD96728.1|  502|Homo sapiens cytochrome P450, family...   155   3e-37
AC005020-1|AAS02016.1|  502|Homo sapiens unknown protein.             155   3e-37
BC100981-1|AAI00982.1|  393|Homo sapiens CYP3A43 protein protein.     148   3e-35
AY390425-1|AAQ92353.1|  503|Homo sapiens cytochrome P450 CYP3A43...   146   1e-34
AY390424-1|AAQ92352.1|  503|Homo sapiens cytochrome P450 CYP3A43...   146   1e-34
AF337813-1|AAK38841.1|  503|Homo sapiens cytochrome P450 subfami...   146   1e-34
AF319634-1|AAK00325.1|  503|Homo sapiens cytochrome P450 CYP3A43...   146   1e-34
AF280108-1|AAG33009.1|  503|Homo sapiens cytochrome P450 subfami...   146   1e-34
AC011904-4|AAS07395.1|  503|Homo sapiens unknown protein.             146   1e-34
AF280109-1|AAG33010.1|  504|Homo sapiens cytochrome P450 subfami...   142   3e-33
AC011904-5|AAS07394.1|  504|Homo sapiens unknown protein.             142   3e-33
AF233624-1|AAF99278.1|  534|Homo sapiens thromboxane synthase pr...   119   2e-26
AF233621-1|AAF99275.1|  534|Homo sapiens thromboxane synthase pr...   119   2e-26
M80647-1|AAA60618.1|  534|Homo sapiens thromboxane synthase prot...   119   2e-26
BC041157-1|AAH41157.1|  534|Homo sapiens thromboxane A synthase ...   119   2e-26
BC014117-1|AAH14117.1|  466|Homo sapiens TBXAS1 protein protein.      119   2e-26
AK223466-1|BAD97186.1|  534|Homo sapiens thromboxane A synthase ...   119   2e-26
AF233622-1|AAF99276.1|  534|Homo sapiens thromboxane synthase pr...   119   2e-26
AF233620-1|AAF99274.1|  534|Homo sapiens thromboxane synthase pr...   119   2e-26
AF233619-1|AAF99273.1|  534|Homo sapiens thromboxane synthase pr...   119   2e-26
AF233618-1|AAF99272.1|  534|Homo sapiens thromboxane synthase pr...   119   2e-26
AF233617-1|AAF99271.1|  534|Homo sapiens thromboxane synthase pr...   119   2e-26
AF233616-1|AAF99270.1|  534|Homo sapiens thromboxane synthase pr...   119   2e-26
AF233615-1|AAF99269.1|  534|Homo sapiens thromboxane synthase pr...   119   2e-26
AF233625-1|AAF99279.1|  534|Homo sapiens thromboxane synthase pr...   118   3e-26
AF233623-1|AAF99277.1|  534|Homo sapiens thromboxane synthase pr...   117   6e-26
D34625-1|BAA07011.1|  533|Homo sapiens thromboxane synthase prot...   117   8e-26
AJ563378-3|CAD91347.1|  173|Homo sapiens hypothetical protein pr...   110   9e-24
AJ563378-2|CAD91647.1|  160|Homo sapiens cytochrome P450 protein.     110   9e-24
AY358631-1|AAQ88994.1|  505|Homo sapiens EPSW3060 protein.            109   2e-23
AY262056-1|AAO89257.1|  505|Homo sapiens cytochrome P450 protein.     109   2e-23
AL450996-2|CAH71036.1|  505|Homo sapiens cytochrome P450, family...   109   2e-23
AL135960-6|CAI19734.1|  505|Homo sapiens cytochrome P450, family...   109   2e-23
BC016853-1|AAH16853.1|  524|Homo sapiens CYP4F11 protein protein.     105   3e-22
AF236085-1|AAG15889.1|  524|Homo sapiens CYP4F11 protein.             105   3e-22
AF133298-1|AAD49566.1|  520|Homo sapiens cytochrome P450 protein.     101   4e-21
BC035350-1|AAH35350.1|  524|Homo sapiens cytochrome P450, family...   101   6e-21
BC028102-1|AAH28102.1|  509|Homo sapiens cytochrome P450, family...   101   6e-21
AY358977-1|AAQ89336.1|  524|Homo sapiens CYP4F12 protein.             101   6e-21
AY358537-1|AAQ88901.1|  509|Homo sapiens EFSW1929 protein.            101   6e-21
AY008841-1|AAG33247.1|  524|Homo sapiens cytochrome P450 isoform...   101   6e-21
AM040940-1|CAJ13826.1|  509|Homo sapiens cytochrome P450 protein.     101   6e-21
AL450996-1|CAH71035.1|  509|Homo sapiens cytochrome P450, family...   101   6e-21
AK131355-1|BAD18508.1|  508|Homo sapiens protein ( Homo sapiens ...   101   6e-21
AK098065-1|BAC05226.1|  509|Homo sapiens protein ( Homo sapiens ...   101   6e-21
AK091806-1|BAC03751.1|  444|Homo sapiens protein ( Homo sapiens ...   101   6e-21
AC004523-1|AAC11543.1|  458|Homo sapiens F22329_1 protein.            101   6e-21
AB035131-1|BAB18270.1|  524|Homo sapiens cytochrome P450 protein.     101   6e-21
AB035130-1|BAB18269.1|  524|Homo sapiens cytochrome P450 protein.     101   6e-21
X16699-1|CAA34672.1|  511|Homo sapiens protein ( Human mRNA for ...    98   5e-20
J02871-1|AAA35712.1|  511|Homo sapiens protein ( Human lung cyto...    98   5e-20
DQ518907-1|ABF47106.1|  511|Homo sapiens cytochrome P450, family...    98   5e-20
BC017758-1|AAH17758.1|  512|Homo sapiens cytochrome P450, family...    98   5e-20
AY151049-1|AAN72312.1|  497|Homo sapiens pulmonary cytochrome P4...    98   5e-20
AY151048-1|AAN72311.1|  512|Homo sapiens pulmonary cytochrome P4...    98   5e-20
AY064485-1|AAL57720.1|  511|Homo sapiens cytochrome P450 protein.      98   5e-20
AL593856-7|CAI16983.1|  497|Homo sapiens cytochrome P450, family...    98   5e-20
AL593856-6|CAI16982.1|  512|Homo sapiens cytochrome P450, family...    98   5e-20
AL593856-5|CAI16981.1|  511|Homo sapiens cytochrome P450, family...    98   5e-20
AL356793-4|CAI22559.1|  511|Homo sapiens cytochrome P450, family...    98   5e-20
AL356793-3|CAI22557.1|  512|Homo sapiens cytochrome P450, family...    98   5e-20
AL356793-2|CAI22558.1|  497|Homo sapiens cytochrome P450, family...    98   5e-20
AF491285-1|AAM09532.1|  511|Homo sapiens cytochrome P450 protein.      98   5e-20
AY064486-1|AAL57721.1|  511|Homo sapiens cytochrome P450 protein.      97   7e-20
AY792513-1|AAV40834.1|  520|Homo sapiens cytochrome P450, family...    95   5e-19
AF054821-1|AAC08589.1|  520|Homo sapiens cytochrome P-450 protein.     95   5e-19
D12620-1|BAA02144.1|  520|Homo sapiens cytochrome P-450LTBV prot...    94   9e-19
BC060857-1|AAH60857.1|  525|Homo sapiens cytochrome P450, family...    94   9e-19
AY422002-1|AAR31180.1|  525|Homo sapiens cytochrome P450 4V2 pro...    94   9e-19
AK126473-1|BAC86562.1|  503|Homo sapiens protein ( Homo sapiens ...    94   9e-19
AK122600-1|BAC85487.1|  525|Homo sapiens protein ( Homo sapiens ...    94   9e-19
AB002461-1|BAA25991.1|  520|Homo sapiens leukotriene B4 omega-hy...    94   9e-19
AB002454-1|BAA25990.1|  520|Homo sapiens leukotriene B4 omega-hy...    94   9e-19
U02388-1|AAC50052.2|  520|Homo sapiens cytochrome P450 4F2 protein.    92   4e-18
AF280110-1|AAG33011.1|  420|Homo sapiens cytochrome P450 subfami...    92   4e-18
D26480-1|BAA05490.1|  520|Homo sapiens leukotriene B4 omega-hydr...    91   6e-18
BC067440-1|AAH67440.1|  520|Homo sapiens cytochrome P450, family...    91   6e-18
BC067439-1|AAH67439.1|  520|Homo sapiens cytochrome P450, family...    91   6e-18
BC067437-1|AAH67437.1|  520|Homo sapiens cytochrome P450, family...    91   6e-18
AF467894-1|AAL67578.1|  520|Homo sapiens cytochrome P450, subfam...    91   6e-18
AC005336-1|AAC27730.1|  520|Homo sapiens CYP4F2 protein.               91   6e-18
AB015306-1|BAA75823.1|  520|Homo sapiens Leukotriene B4 omega-hy...    91   6e-18
BC132767-1|AAI32768.1|  544|Homo sapiens cytochrome P450, family...    91   8e-18
AY343323-1|AAQ21380.1|  544|Homo sapiens cytochrome P450 protein.      91   8e-18
BC022539-1|AAH22539.1|  500|Homo sapiens cytochrome P450, family...    84   7e-16
AF094480-1|AAD41244.1|  500|Homo sapiens cholesterol 24-hydroxyl...    84   7e-16
BC100982-1|AAI00983.1|  280|Homo sapiens CYP3A43 protein protein.      84   9e-16
L13286-1|AAA62379.1|  513|Homo sapiens 1,25-dihydroxyvitamin D3 ...    81   5e-15
S67623-1|AAB29308.1|  257|Homo sapiens 25-hydroxyvitamin D 24-hy...    81   9e-15
AY858838-1|AAW50795.1|  372|Homo sapiens vitamin D 24-hydroxylas...    81   9e-15
AL138805-3|CAB91829.1|  514|Homo sapiens cytochrome P450, family...    81   9e-15
AL138805-1|CAM27342.1|  372|Homo sapiens cytochrome P450, family...    81   9e-15
BC093896-1|AAH93896.1|  531|Homo sapiens cytochrome P450, family...    80   1e-14
BC093894-1|AAH93894.1|  531|Homo sapiens cytochrome P450, family...    80   1e-14
BC069351-1|AAH69351.1|  531|Homo sapiens cytochrome P450, family...    80   1e-14
AK096820-1|BAC04868.1|  531|Homo sapiens protein ( Homo sapiens ...    80   1e-14
BC104909-1|AAI04910.1|  501|Homo sapiens cytochrome P450, family...    79   2e-14
BC104907-1|AAI04908.1|  501|Homo sapiens cytochrome P450, family...    79   2e-14
AY323817-1|AAQ23114.1|  501|Homo sapiens cytochrome P450 2R1 pro...    79   2e-14
X59812-1|CAA42481.1|  530|Homo sapiens Vitamin D3 25-hydroxylase...    77   8e-14
M62401-1|AAA52142.1|  531|Homo sapiens sterol 27-hydroxylase pro...    77   8e-14
BC051851-1|AAH51851.1|  531|Homo sapiens cytochrome P450, family...    77   8e-14
BC040430-1|AAH40430.1|  531|Homo sapiens cytochrome P450, family...    77   8e-14
BC117165-1|AAI17166.1|  494|Homo sapiens cytochrome P450, family...    77   1e-13
AY178622-1|AAO21126.1|  531|Homo sapiens steroid hydroxylase pro...    76   2e-13
AK090886-1|BAC03539.1|  337|Homo sapiens protein ( Homo sapiens ...    75   6e-13
S67581-1|AAB29503.1|  591|Homo sapiens fatty acid omega-hydroxyl...    74   8e-13
S67580-1|AAB29502.1|  519|Homo sapiens fatty acid omega-hydroxyl...    74   8e-13
DQ680079-1|ABG25922.1|  347|Homo sapiens truncated cytochrome P4...    74   1e-12
AF280111-1|AAG33012.1|  250|Homo sapiens cytochrome P450 subfami...    74   1e-12
L04751-1|AAA58436.1|  519|Homo sapiens cytochrome P450 protein.        73   2e-12
D26481-1|BAA05491.1|  519|Homo sapiens fatty acids omega-hydroxy...    73   2e-12
AY369778-1|AAQ56847.1|  519|Homo sapiens cytochrome P450, family...    73   2e-12
AL731892-3|CAH72778.1|  519|Homo sapiens cytochrome P450, family...    73   2e-12
AF478474-1|AAL84813.1|  503|Homo sapiens mutated cytochrome P-45...    73   2e-12
M33317-1|AAA52138.1|  494|Homo sapiens CYP2A protein.                  73   2e-12
M32879-1|AAA52149.1|  503|Homo sapiens CYP11B1 protein.                73   2e-12
BC096287-1|AAH96287.1|  503|Homo sapiens cytochrome P450, family...    73   2e-12
BC096285-1|AAH96285.1|  574|Homo sapiens CYP11B1 protein protein.      73   2e-12
AY280372-1|AAQ21368.1|  519|Homo sapiens cytochrome P450 4A22 pr...    73   2e-12
AY280371-1|AAQ21367.1|  519|Homo sapiens cytochrome P450 4A22K p...    73   2e-12
AF525488-1|AAO16078.1|  519|Homo sapiens cytochrome P450, subfam...    73   2e-12
X55764-1|CAA39290.1|  503|Homo sapiens protein ( Human mRNA for ...    72   3e-12
X13930-1|CAA32118.1|  494|Homo sapiens protein ( Human CYP2A4 mR...    72   3e-12
X13929-1|CAA32117.1|  448|Homo sapiens P-450 IIA3 protein (1 is ...    72   3e-12
X13897-1|CAA32097.1|  489|Homo sapiens protein ( Human mRNA for ...    72   3e-12
M33318-1|AAA52067.1|  494|Homo sapiens CYP2A protein.                  72   3e-12
BC096256-1|AAH96256.1|  494|Homo sapiens cytochrome P450, family...    72   3e-12
BC096255-1|AAH96255.1|  494|Homo sapiens cytochrome P450, family...    72   3e-12
BC096254-1|AAH96254.1|  494|Homo sapiens cytochrome P450, family...    72   3e-12
BC096253-1|AAH96253.3|  494|Homo sapiens cytochrome P450, family...    72   3e-12
X54741-1|CAA38539.1|  503|Homo sapiens aldosterone  synthase (P-...    72   4e-12
D13752-1|BAA02899.1|  503|Homo sapiens steroid 18-hydroxylase pr...    72   4e-12
J02843-1|AAA52155.1|  493|Homo sapiens protein ( Human cytochrom...    71   7e-12
J02625-1|AAA35743.1|  493|Homo sapiens protein ( Human cytochrom...    71   7e-12
DQ515958-1|ABF47105.1|  493|Homo sapiens cytochrome P450, family...    71   7e-12
DQ149222-1|AAZ77710.1|  493|Homo sapiens cytochrome P450 2E1 pro...    71   7e-12
AL161645-2|CAH70047.1|  493|Homo sapiens cytochrome P450, family...    71   7e-12
AF182276-1|AAF13601.1|  493|Homo sapiens cytochrome P450-2E1 pro...    71   7e-12
AF182275-1|AAF13600.1|  494|Homo sapiens cytochrome P450-2A6 pro...    71   7e-12
AF084225-1|AAD13753.1|  462|Homo sapiens cytochrome P450 2E1 pro...    71   7e-12
BC067433-1|AAH67433.1|  493|Homo sapiens cytochrome P450, family...    71   9e-12
AL358613-3|CAH72804.1|  428|Homo sapiens cytochrome P450, family...    71   9e-12
AL358613-2|CAH72803.1|  497|Homo sapiens cytochrome P450, family...    71   9e-12
AF005418-1|AAB88881.1|  497|Homo sapiens retinoic acid hydroxyla...    71   9e-12
M61858-1|AAA52145.1|  370|Homo sapiens CYP2C17 protein.                69   2e-11
AY513608-1|AAR90939.1|  494|Homo sapiens cytochrome P450 2A13 va...    69   3e-11
AY513606-1|AAR90937.1|  494|Homo sapiens cytochrome P450 2A13 va...    69   3e-11
AY513605-1|AAR90936.1|  494|Homo sapiens cytochrome P450 2A13 va...    69   3e-11
AY513604-1|AAR90935.1|  494|Homo sapiens cytochrome P450 2A13 va...    69   3e-11
AF209774-1|AAG35775.1|  494|Homo sapiens cytochrome P450 2A13 pr...    69   3e-11
M32881-1|AAA35741.1|  503|Homo sapiens protein ( Human steroid 1...    69   4e-11
D13705-1|BAA02864.1|  521|Homo sapiens fatty acid omega-hydroxyl...    69   4e-11
BC067435-1|AAH67435.1|  493|Homo sapiens cytochrome P450, family...    69   4e-11
AY513609-1|AAR90940.1|  494|Homo sapiens cytochrome P450 2A13 va...    69   4e-11
AL135960-10|CAI19737.1|  519|Homo sapiens cytochrome P450, famil...    69   4e-11
AF208532-1|AAF76722.1|  519|Homo sapiens fatty acid omega-hydrox...    68   5e-11
X05367-1|CAA28965.1|  521|Homo sapiens desmolase protein.              68   7e-11
M28253-1|AAA36404.1|  239|Homo sapiens cytochrome P-450-scc prot...    68   7e-11
M14565-1|AAA52162.1|  521|Homo sapiens CYP11A protein.                 68   7e-11
BC032329-1|AAH32329.1|  521|Homo sapiens cytochrome P450, family...    68   7e-11
M80646-1|AAA60617.1|  460|Homo sapiens thromboxane synthase prot...    67   1e-10
X65962-1|CAA46778.1|  356|Homo sapiens cytochrome P-450 II C pro...    66   2e-10
L07093-1|AAA36660.1|  468|Homo sapiens cytochrome P450 protein.        66   2e-10
AY796203-1|AAV41877.1|  490|Homo sapiens cytochrome P450, family...    66   2e-10
AL583836-2|CAH74068.1|  490|Homo sapiens cytochrome P450, family...    66   2e-10
AL133513-2|CAH73444.1|  490|Homo sapiens cytochrome P450, family...    66   2e-10
U22028-1|AAB40519.1|  494|Homo sapiens cytochrome P450 protein.        66   2e-10
M61854-1|AAB59426.1|  490|Homo sapiens cytochrome protein.             66   2e-10
L39102-1|AAL31348.1|  217|Homo sapiens S-mephenytoin 4-hydroxyla...    66   2e-10
AY288916-1|AAP31972.1|  508|Homo sapiens cytochrome P450, family...    66   2e-10
AF256213-1|AAG00416.1|  508|Homo sapiens 25- hydroxyvitamin D-1-...    66   2e-10
AF246895-1|AAF64299.1|  508|Homo sapiens 25-hydroxyvitamin D-1-a...    66   2e-10
AF027152-1|AAC51854.1|  508|Homo sapiens P450 25-hydroxyvitamin ...    66   2e-10
AF020192-1|AAC51853.1|  508|Homo sapiens 25-hydroxyvitamin D-1-a...    66   2e-10
AB006987-1|BAA23418.1|  508|Homo sapiens 25-hydroxyvitamin D3 1-...    66   2e-10
AB005990-1|BAA22657.1|  508|Homo sapiens 25-hydroxyvitamin D3 1a...    66   2e-10
AB005989-1|BAA22656.1|  508|Homo sapiens 25-hydroxyvitamin D3 1a...    66   2e-10
AB005038-1|BAA23416.1|  508|Homo sapiens 25-hydroxyvitamin D3 1-...    66   2e-10
BC025761-1|AAH25761.2|  490|Homo sapiens cytochrome P450, family...    66   3e-10
AM183950-1|CAJ75804.1|  494|Homo sapiens steroid 21-hydroxylase,...    66   3e-10
AJ563379-2|CAD91649.1|   84|Homo sapiens cytochrome P450 protein.      66   3e-10
M61856-1|AAB59356.1|  490|Homo sapiens cytochrome protein.             65   3e-10
BX538127-1|CAD98029.1|  310|Homo sapiens hypothetical protein pr...    65   3e-10
BC096260-1|AAH96260.1|  431|Homo sapiens CYP2C18 protein protein.      65   3e-10
BC096258-1|AAH96258.1|  490|Homo sapiens cytochrome P450, family...    65   3e-10
BC096257-1|AAH96257.1|  490|Homo sapiens cytochrome P450, family...    65   3e-10
BC069666-1|AAH69666.1|  490|Homo sapiens cytochrome P450, family...    65   3e-10
AL583836-1|CAH74067.1|  490|Homo sapiens cytochrome P450, family...    65   3e-10
AK223510-1|BAD97230.1|  490|Homo sapiens cytochrome P450, family...    65   3e-10
U37143-1|AAC50370.2|  502|Homo sapiens cytochrome P450 monooxyge...    65   5e-10
S46963-1|AAB23864.2|  477|Homo sapiens cytochrome P-450 protein.       65   5e-10
L16876-1|AAA02630.1|  490|Homo sapiens cytochrome P-4502C18 prot...    65   5e-10
D00173-1|BAA00123.1|  487|Homo sapiens cytochrome P-450 protein.       65   5e-10
BC125054-1|AAI25055.1|  490|Homo sapiens cytochrome P450, family...    65   5e-10
BC032594-1|AAH32594.1|  502|Homo sapiens cytochrome P450, family...    65   5e-10
AY702706-1|AAT94065.1|  490|Homo sapiens cytochrome P450, family...    65   5e-10
AY426985-1|AAQ93356.1|  502|Homo sapiens cytochrome P450, family...    65   5e-10
AY341248-1|AAP88931.1|  490|Homo sapiens cytochrome P450, family...    65   5e-10
AL359672-1|CAH71303.1|  490|Homo sapiens cytochrome P450, family...    65   5e-10
AF272142-1|AAM44456.1|  502|Homo sapiens cytochrome P450 protein.      65   5e-10
M29874-1|AAA52144.1|  491|Homo sapiens CYP2B protein.                  64   6e-10
K03192-1|AAA52147.1|  331|Homo sapiens CYP1A1 protein.                 64   6e-10
DQ298753-1|ABB84469.1|  491|Homo sapiens cytochrome P450, family...    64   6e-10
BC067431-1|AAH67431.1|  491|Homo sapiens cytochrome P450, family...    64   6e-10
BC067430-1|AAH67430.1|  491|Homo sapiens cytochrome P450, family...    64   6e-10
AF372573-1|AAL69652.1|  495|Homo sapiens cytochrome P450 2F1 pro...    64   6e-10
AF182277-1|AAF13602.1|  491|Homo sapiens cytochrome P450-2B6 pro...    64   6e-10
AC023172-1|AAF32444.1|  491|Homo sapiens CYP2B6 protein.               64   6e-10
AB080265-1|BAB85489.1|  502|Homo sapiens cytochrome P450 2J2 pro...    64   6e-10
X58906-1|CAA41709.1|  495|Homo sapiens steroid 21-monooxygenase ...    64   8e-10
M28548-1|AAA52065.1|  495|Homo sapiens protein ( Human mutant 21...    64   8e-10
J02906-1|AAA52156.1|  491|Homo sapiens CYP2F1 protein.                 64   8e-10
M26856-1|AAA52064.1|  495|Homo sapiens protein ( Human 21-hydrox...    64   1e-09
M24667-1|AAA52148.1|  256|Homo sapiens steroid 11-beta-hydroxyla...    64   1e-09
M21550-1|AAA52063.1|  495|Homo sapiens CYP21 protein.                  64   1e-09
M13936-1|AAA59695.1|  494|Homo sapiens CYP21P protein.                 64   1e-09
BX679671-8|CAM26071.1|  464|Homo sapiens cytochrome P450, family...    64   1e-09
BX679671-7|CAM26070.1|  494|Homo sapiens cytochrome P450, family...    64   1e-09
BC125182-1|AAI25183.1|  494|Homo sapiens cytochrome P450, family...    64   1e-09
BC125181-1|AAI25182.1|  495|Homo sapiens cytochrome P450, family...    64   1e-09
AM183951-1|CAJ75805.1|  494|Homo sapiens steroid 21-hydroxylase,...    64   1e-09
AM183947-1|CAJ75801.1|  494|Homo sapiens steroid 21-hydroxylase,...    64   1e-09
AM183946-1|CAJ75800.1|  494|Homo sapiens steroid 21-hydroxylase,...    64   1e-09
AM183945-1|CAJ75799.1|  494|Homo sapiens steroid 21-hydroxylase,...    64   1e-09
AM086565-1|CAJ31104.1|  494|Homo sapiens steroid 21-hydroxylase,...    64   1e-09
AM086564-1|CAJ31103.1|  494|Homo sapiens steroid 21-hydroxylase,...    64   1e-09
AL929593-2|CAI41778.1|  465|Homo sapiens cytochrome P450, family...    64   1e-09
AL929593-1|CAI41779.1|  495|Homo sapiens cytochrome P450, family...    64   1e-09
AL662849-19|CAI17480.1|  465|Homo sapiens cytochrome P450, famil...    64   1e-09
AL662849-18|CAI17479.1|  495|Homo sapiens cytochrome P450, famil...    64   1e-09
AL645922-24|CAI41754.1|  495|Homo sapiens cytochrome P450, famil...    64   1e-09
AL645922-23|CAI41755.1|  465|Homo sapiens cytochrome P450, famil...    64   1e-09
AL049547-7|CAB89301.1|  495|Homo sapiens dJ34F7.3 (cytochrome P4...    64   1e-09
AF077974-1|AAD45405.1|  403|Homo sapiens cytochrome P450 21-hydr...    64   1e-09
AF019413-2|AAB67982.1|  495|Homo sapiens cytochrome P450 21-hydr...    64   1e-09
M21939-1|AAA52158.1|  485|Homo sapiens CYP2C protein.                  63   1e-09
M15331-1|AAA52157.1|  485|Homo sapiens CYP2C protein.                  63   1e-09
AM183949-1|CAJ75803.1|  494|Homo sapiens steroid 21-hydroxylase,...    63   1e-09
M21940-1|AAA52159.1|  383|Homo sapiens CYP2C protein.                  63   2e-09
BC109205-1|AAI09206.1|  512|Homo sapiens cytochrome P450, family...    63   2e-09
BC069443-1|AAH69443.1|  512|Homo sapiens cytochrome P450, family...    63   2e-09
AF252297-1|AAF76003.1|  512|Homo sapiens cytochrome P450 retinoi...    63   2e-09
AC007002-1|AAY14690.1|  512|Homo sapiens unknown protein.              63   2e-09
AK054616-1|BAB70774.1|  465|Homo sapiens protein ( Homo sapiens ...    62   3e-09
U22027-1|AAB40518.1|  494|Homo sapiens cytochrome P450 protein.        62   4e-09
BC106758-1|AAI06759.1|  497|Homo sapiens cytochrome P450, family...    62   4e-09
AM183948-1|CAJ75802.1|  494|Homo sapiens steroid 21-hydroxylase ...    62   4e-09
M17252-1|AAA59985.1|  230|Homo sapiens CYP21 protein.                  61   6e-09
AC004914-2|AAP21887.1|  311|Homo sapiens unknown protein.              61   6e-09
AC004914-1|AAD21788.1|  348|Homo sapiens unknown protein.              61   6e-09
M74055-1|AAA36742.1|  229|Homo sapiens thromboxane synthase prot...    61   8e-09
M63871-1|AAA59984.1|  508|Homo sapiens CYP17 protein.                  61   8e-09
M31153-1|AAA52140.1|  508|Homo sapiens CYP17 protein.                  61   8e-09
M19489-1|AAA36405.1|  508|Homo sapiens CYP17 protein.                  61   8e-09
M14564-1|AAA52151.1|  508|Homo sapiens CYP17 protein.                  61   8e-09
DQ530598-1|ABF50972.1|  508|Homo sapiens cytochrome P450, family...    61   8e-09
DQ211353-1|ABB01370.1|  497|Homo sapiens cytochrome P450 2D6 pro...    61   8e-09
BT020000-1|AAV38803.1|  508|Homo sapiens cytochrome P450, family...    61   8e-09
BC063388-1|AAH63388.1|  508|Homo sapiens cytochrome P450, family...    61   8e-09
BC062997-1|AAH62997.1|  508|Homo sapiens cytochrome P450, family...    61   8e-09
BC033691-1|AAH33691.1|  504|Homo sapiens cytochrome P450, family...    61   8e-09
AY358603-1|AAQ88966.1|  504|Homo sapiens Cytochrome p450 protein.      61   8e-09
AL358790-3|CAI52498.1|  508|Homo sapiens cytochrome P450, family...    61   8e-09
AK027605-1|BAB55227.1|  564|Homo sapiens protein ( Homo sapiens ...    61   8e-09
AF335278-1|AAK13498.1|  504|Homo sapiens cytochrome P450 2S1 pro...    61   8e-09
X08006-1|CAA30807.1|  497|Homo sapiens cytochrome P450 db1 protein.    60   1e-08
U22029-1|AAB40520.1|  494|Homo sapiens cytochrome P450 protein.        60   1e-08
M33388-1|AAA53500.1|  497|Homo sapiens cytochrome P450 IID6 prot...    60   1e-08
M33189-1|AAA35737.1|  500|Homo sapiens protein ( Human debrisoqu...    60   1e-08
M24499-1|AAA36403.1|  373|Homo sapiens cytochrome P450db1 protein.     60   1e-08
M20403-1|AAA52153.1|  497|Homo sapiens CYP2D protein.                  60   1e-08
L36085-1|AAC01761.1|  441|Homo sapiens thromboxane A2 synthase p...    60   1e-08
DQ282162-1|ABB77909.1|  500|Homo sapiens cytochrome P450 2D6 pro...    60   1e-08
DQ282160-1|ABB77908.1|  497|Homo sapiens cytochrome P450 2D6 pro...    60   1e-08
DQ282159-1|ABB77907.1|  497|Homo sapiens cytochrome P450 2D6 pro...    60   1e-08
DQ282158-1|ABB77906.1|  497|Homo sapiens cytochrome P450 2D6 pro...    60   1e-08
DQ282157-1|ABB77905.1|  497|Homo sapiens cytochrome P450 2D6 pro...    60   1e-08
DQ282156-1|ABB77904.1|  497|Homo sapiens cytochrome P450 2D6 pro...    60   1e-08
DQ282155-1|ABB77903.1|  497|Homo sapiens cytochrome P450 2D6 pro...    60   1e-08
DQ282154-1|ABB77902.1|  497|Homo sapiens cytochrome P450 2D6 pro...    60   1e-08
DQ282152-1|ABB77900.1|  497|Homo sapiens cytochrome P450 2D6 pro...    60   1e-08
DQ282151-1|ABB77899.1|  496|Homo sapiens cytochrome P450 2D6 pro...    60   1e-08
DQ282147-1|ABB77898.1|  497|Homo sapiens cytochrome P450 2D6 pro...    60   1e-08
DQ282146-1|ABB77897.1|  497|Homo sapiens cytochrome P450 2D6 pro...    60   1e-08
DQ282145-1|ABB77896.1|  497|Homo sapiens cytochrome P450 2D6 pro...    60   1e-08
DQ282144-1|ABB77895.1|  497|Homo sapiens cytochrome P450 2D6 pro...    60   1e-08
DQ211354-2|ABB01372.1|  497|Homo sapiens cytochrome P450 2D6 pro...    60   1e-08
DQ211353-2|ABB01371.1|  497|Homo sapiens cytochrome P450 2D6 pro...    60   1e-08
CR456430-1|CAG30316.1|  446|Homo sapiens CYP2D6 protein.               60   1e-08
BC126858-1|AAI26859.1|  497|Homo sapiens cytochrome P450, family...    60   1e-08
BC106757-1|AAI06758.1|  446|Homo sapiens cytochrome P450, family...    60   1e-08
BC075024-1|AAH75024.1|  497|Homo sapiens cytochrome P450, family...    60   1e-08
BC075023-1|AAH75023.1|  497|Homo sapiens cytochrome P450, family...    60   1e-08
BC067432-1|AAH67432.1|  497|Homo sapiens cytochrome P450, family...    60   1e-08
BC066877-1|AAH66877.1|  446|Homo sapiens CYP2D6 protein protein.       60   1e-08
AY545216-1|AAS55001.1|  497|Homo sapiens cytochrome P4502D6 prot...    60   1e-08
AB209492-1|BAD92729.1|  566|Homo sapiens Debrisoquine 4-hydroxyl...    60   1e-08
U51692-1|AAC50951.1|  503|Homo sapiens lanosterol 14-alpha demet...    60   1e-08
DQ282153-1|ABB77901.1|  497|Homo sapiens cytochrome P450 2D6 pro...    60   1e-08
AY220845-1|AAO49806.1|  516|Homo sapiens cytochrome P450 protein.      60   1e-08
M12792-1|AAB59440.1|  494|Homo sapiens steroid 21-hydroxylase pr...    60   2e-08
BC032322-1|AAH32322.1|  509|Homo sapiens cytochrome P450, family...    60   2e-08
Y00498-1|CAA68550.1|  490|Homo sapiens IIC2 protein.                   59   2e-08
U23942-1|AAB39951.1|  509|Homo sapiens lanosterol 14-demethylase...    59   2e-08
M21942-1|AAA52161.1|  462|Homo sapiens CYP2C protein.                  59   2e-08
M17397-1|AAA35739.1|  490|Homo sapiens protein ( Human cytochrom...    59   2e-08
D55653-1|BAA09512.1|  509|Homo sapiens lanosterol 14-demethylase...    59   2e-08
BC020596-1|AAH20596.1|  490|Homo sapiens cytochrome P450, family...    59   2e-08
AY514490-1|AAR89907.1|  490|Homo sapiens cytochrome P450, family...    59   2e-08
AL359672-5|CAH71307.1|  490|Homo sapiens cytochrome P450, family...    59   2e-08
AC000120-2|AAB46356.1|  509|Homo sapiens unknown protein.              59   2e-08
X51535-1|CAA35915.1|  210|Homo sapiens cytochrome P-450 HPH (120...    59   3e-08
M21941-1|AAA52160.1|  480|Homo sapiens CYP2C protein.                  58   4e-08
AK127151-1|BAC86855.1|  146|Homo sapiens protein ( Homo sapiens ...    57   9e-08
BC039307-1|AAH39307.1|  372|Homo sapiens FLJ16008 protein protein.     55   4e-07
AK131190-1|BAD18388.1|  372|Homo sapiens .-.-).  protein.              55   4e-07
K03191-1|AAA52139.1|  512|Homo sapiens CYP1A1 protein.                 54   7e-07
X04300-1|CAA27843.1|  512|Homo sapiens P-450 c protein.                54   9e-07
X02612-1|CAA26458.1|  512|Homo sapiens cytochrome P(1)-450 protein.    54   9e-07
EF094025-1|ABK41999.1|  512|Homo sapiens cytochrome P450, family...    54   9e-07
BC128535-1|AAI28536.1|  143|Homo sapiens LOC283480 protein protein.    54   9e-07
BC023019-1|AAH23019.1|  512|Homo sapiens cytochrome P450, family...    54   9e-07
AY310359-1|AAQ76692.1|  484|Homo sapiens cytochrome P450 1A1 var...    54   9e-07
AK223113-1|BAD96833.1|  512|Homo sapiens cytochrome P450, family...    54   9e-07
AF253322-1|AAK25727.1|  512|Homo sapiens cytochrome P450 protein.      54   9e-07
L16883-1|AAD13467.1|  169|Homo sapiens cytochrome P-450 2C protein.    54   1e-06
AK223108-1|BAD96828.1|  512|Homo sapiens cytochrome P450, family...    52   3e-06
AF176805-1|AAK11850.1|  506|Homo sapiens oxysterol 7alpha-hydrox...    52   3e-06
AF127090-1|AAD20021.1|  506|Homo sapiens oxysterol 7alpha-hydrox...    52   3e-06
AF029403-1|AAC95426.1|  506|Homo sapiens oxysterol 7alpha-hydrox...    52   3e-06
BC041158-1|AAH41158.1|  455|Homo sapiens CYP4A11 protein protein.      51   6e-06
AL731892-4|CAH72779.1|  455|Homo sapiens cytochrome P450, family...    51   6e-06
AB209700-1|BAD92937.1|  336|Homo sapiens cytochrome P450, family...    51   6e-06
M93133-1|AAA58435.1|  504|Homo sapiens cholesterol 7-alpha hydro...    50   1e-05
BC112184-1|AAI12185.1|  504|Homo sapiens cytochrome P450, family...    50   1e-05
BC101777-1|AAI01778.1|  504|Homo sapiens cytochrome P450, family...    50   1e-05
BC096259-1|AAH96259.1|  443|Homo sapiens CYP2C18 protein protein.      50   1e-05
BC067444-1|AAH67444.1|  501|Homo sapiens cytochrome P450, family...    50   1e-05
BC067442-1|AAH67442.1|  501|Homo sapiens cytochrome P450, family...    50   1e-05
AM236047-1|CAJ84704.1|  251|Homo sapiens cytochrome P450 1A1 pro...    50   1e-05
AF090320-1|AAD19877.1|  501|Homo sapiens sterol 12-alpha-hydroxy...    50   1e-05
AF090318-1|AAC63037.1|  462|Homo sapiens sterol 12-alpha hydroxy...    50   1e-05
Z00036-1|CAA77335.1|  515|Homo sapiens protein ( Human mRNA for ...    50   1e-05
X71480-1|CAA50586.1|  141|Homo sapiens cytochrome P450 protein.        50   1e-05
M55053-1|AAA52146.1|  515|Homo sapiens cytochrome P3-450 protein.      50   1e-05
M31667-1|AAA52163.1|  515|Homo sapiens CYP1A2 protein.                 50   1e-05
L00389-1|AAA35738.1|  516|Homo sapiens protein ( Human cytochrom...    50   1e-05
DQ022432-1|AAY26399.1|  516|Homo sapiens cytochrome P450, family...    50   1e-05
BC067428-1|AAH67428.1|  516|Homo sapiens cytochrome P450, family...    50   1e-05
BC067427-1|AAH67427.1|  516|Homo sapiens cytochrome P450, family...    50   1e-05
BC067426-1|AAH67426.1|  516|Homo sapiens cytochrome P450, family...    50   1e-05
BC067425-1|AAH67425.1|  516|Homo sapiens cytochrome P450, family...    50   1e-05
BC067424-1|AAH67424.1|  516|Homo sapiens cytochrome P450, family...    50   1e-05
BC029155-1|AAH29155.1|  489|Homo sapiens Unknown (protein for IM...    50   1e-05
AF253322-2|AAK25728.1|  516|Homo sapiens cytochrome P450 protein.      50   1e-05
AL135960-9|CAI19736.1|  421|Homo sapiens cytochrome P450, family...    50   2e-05
AF182274-1|AAF13599.1|  516|Homo sapiens cytochrome P450-1A2 pro...    50   2e-05
Y07508-1|CAA68807.1|  503|Homo sapiens protein ( Human mRNA for ...    49   2e-05
X13589-1|CAA31929.1|  503|Homo sapiens protein ( Human mRNA for ...    49   2e-05
M30804-1|AAA35728.1|  503|Homo sapiens protein ( Human aromatase...    49   2e-05
M28420-1|AAA52141.1|  419|Homo sapiens cytochrome P-450 aromatas...    49   2e-05
M22246-1|AAA35557.1|  503|Homo sapiens protein ( Human aromatase...    49   2e-05
M18856-1|AAA35556.1|  419|Homo sapiens protein ( Human aromatase...    49   2e-05
J04127-1|AAA52132.1|  503|Homo sapiens CYP19 protein.                  49   2e-05
DQ118405-1|AAZ23558.1|  503|Homo sapiens cytochrome P450 subfami...    49   2e-05
BC107785-1|AAI07786.1|  503|Homo sapiens cytochrome P450, family...    49   2e-05
BC067441-1|AAH67441.1|  501|Homo sapiens cytochrome P450, family...    49   2e-05
BC067434-1|AAH67434.1|  501|Homo sapiens cytochrome P450, family...    49   2e-05
BC035959-1|AAH35959.1|  503|Homo sapiens cytochrome P450, family...    49   2e-05
AY957953-1|AAX44046.1|  503|Homo sapiens cytochrome P450, family...    49   2e-05
M12079-1|AAA52152.1|  191|Homo sapiens POR protein.                    48   4e-05
AL358613-1|CAH72802.2|  522|Homo sapiens cytochrome P450, family...    48   4e-05
BC067429-1|AAH67429.1|  516|Homo sapiens cytochrome P450, family...    48   6e-05
AL135960-11|CAI19738.1|  455|Homo sapiens cytochrome P450, famil...    48   6e-05
X56088-1|CAA39568.1|  504|Homo sapiens cholesterol  7-alpha-hydr...    48   7e-05
AF297052-1|AAG31785.1|  500|Homo sapiens prostacyclin synthase p...    48   7e-05
D84124-1|BAA28219.1|  509|Homo sapiens prostacyclin synthase pro...    47   1e-04
D83402-1|BAA11910.1|  500|Homo sapiens prostacyclin synthase pro...    47   1e-04
D38145-1|BAA07343.1|  500|Homo sapiens prostacyclin synthase pro...    47   1e-04
BC101811-1|AAI01812.1|  500|Homo sapiens prostaglandin I2 (prost...    47   1e-04
BC101809-1|AAI01810.1|  500|Homo sapiens prostaglandin I2 (prost...    47   1e-04
AL118525-1|CAC14162.1|  500|Homo sapiens prostaglandin I2 (prost...    47   1e-04
AK000366-1|BAA91114.1|  408|Homo sapiens protein ( Homo sapiens ...    47   1e-04
AJ877238-1|CAI47002.1|   97|Homo sapiens putative cytochrome P45...    47   1e-04
AF297051-1|AAG31784.1|  500|Homo sapiens prostacyclin synthase p...    47   1e-04
AF297050-1|AAG31783.1|  500|Homo sapiens prostacyclin synthase p...    47   1e-04
AF297049-1|AAG31782.1|  500|Homo sapiens prostacyclin synthase p...    47   1e-04
AF297048-1|AAG31781.1|  500|Homo sapiens prostacyclin synthase p...    47   1e-04
U03688-1|AAA19567.1|  543|Homo sapiens cytochrome P450 protein.        46   2e-04
M12078-1|AAA52154.1|  192|Homo sapiens POR protein.                    46   2e-04
BT020001-1|AAV38804.1|  543|Homo sapiens cytochrome P450, family...    46   2e-04
BT019979-1|AAV38782.1|  543|Homo sapiens cytochrome P450, family...    46   2e-04
BC012049-1|AAH12049.1|  543|Homo sapiens cytochrome P450, family...    46   2e-04
AY356349-1|AAQ55485.1|  522|Homo sapiens cytochrome P450 protein.      46   2e-04
AC009229-2|AAY15039.1|  543|Homo sapiens unknown protein.              46   2e-04
U56438-1|AAC50809.1|  543|Homo sapiens dioxin-inducible cytochro...    46   3e-04
DQ016495-1|AAY34975.1|  195|Homo sapiens cytochrome P450 1B1 pro...    46   3e-04
AY393998-1|AAQ87875.1|  543|Homo sapiens cytochrome P450, family...    46   3e-04
AF450132-1|AAM50512.1|  543|Homo sapiens cytochrome P450 CYP1B1 ...    46   3e-04
BC010358-1|AAH10358.1|  469|Homo sapiens cytochrome P450, family...    44   0.001
AL591242-1|CAH73899.1|  469|Homo sapiens cytochrome P450, family...    44   0.001
AL035670-1|CAI20276.1|  469|Homo sapiens cytochrome P450, family...    44   0.001
AF237982-1|AAF63329.1|  469|Homo sapiens oxysterol 7alpha-hydrox...    44   0.001
BC109084-1|AAI09085.1|  448|Homo sapiens CYP24A1 protein protein.      41   0.006
BC109083-1|AAI09084.1|  448|Homo sapiens CYP24A1 protein protein.      41   0.006
AL138805-2|CAM27343.1|  448|Homo sapiens cytochrome P450, family...    41   0.006
S77409-1|AAB34643.1|  228|Homo sapiens steroid 18-hydroxylase pr...    41   0.009
AK127234-1|BAC86895.1|  130|Homo sapiens ).  protein.                  41   0.009
AY359068-1|AAQ89427.1|  462|Homo sapiens P450-like protein protein.    40   0.011
BC093022-1|AAH93022.1|  416|Homo sapiens CYP20A1 protein protein.      40   0.015
BC033752-1|AAH33752.1|  462|Homo sapiens cytochrome P450, family...    40   0.015
BC020616-1|AAH20616.1|  462|Homo sapiens cytochrome P450, family...    40   0.015
BC096286-1|AAH96286.1|  437|Homo sapiens cytochrome P450, family...    40   0.020
AM233517-1|CAJ80720.1|  175|Homo sapiens cytochrome P450 1A1 pro...    37   0.11 
AF183412-1|AAG09681.1|  435|Homo sapiens cytochrome P450 monooxy...    37   0.11 
AC005336-2|AAC27731.1|   93|Homo sapiens F20191_1, partial CDS p...    36   0.24 
D50111-1|BAA08796.1|   46|Homo sapiens CYP2EI protein.                 35   0.43 
AY871801-1|AAX62803.1|  483|Homo sapiens cytochrome P450 family ...    35   0.56 
AK075063-1|BAC11379.1|  202|Homo sapiens protein ( Homo sapiens ...    33   1.3  
BC053635-1|AAH53635.1|  857|Homo sapiens nucleolar protein 14 pr...    31   5.3  
BC026035-1|AAH26035.1|  806|Homo sapiens NOL14 protein protein.        31   5.3  
AK097373-1|BAC05026.1|  340|Homo sapiens protein ( Homo sapiens ...    31   5.3  
AF040965-1|AAB97011.1|  873|Homo sapiens unknown protein IT12 pr...    31   5.3  
AB000467-1|BAA19121.1|  718|Homo sapiens protein ( Homo sapiens ...    31   5.3  

>M14096-1|AAA35744.1|  503|Homo sapiens protein ( Human cytochrome
           P-450 nifedipine oxidase mRNA, complet cds. ).
          Length = 503

 Score =  165 bits (401), Expect = 2e-40
 Identities = 91/250 (36%), Positives = 140/250 (56%), Gaps = 16/250 (6%)

Query: 128 LGFTIIPKSTSEFFRTLIASTVDYRIKNKVERR-DMIQLLM--QLSTEW------TETEL 178
           L   + P+  + F R  +    + R+++  + R D +QL++  Q S E       ++ EL
Sbjct: 236 LNICVFPREVTNFLRKSVKRMKESRLEDTQKHRVDFLQLMIDSQNSKETESHKALSDLEL 295

Query: 179 AAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYENIGELKY 238
            AQ  +F  AG+ETT + L   ++ELA  P +Q  L EE+ A    K    Y+ + +++Y
Sbjct: 296 VAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEY 355

Query: 239 LDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHMDPIYY 298
           LD V+NET+R +  A+ ++R+C K   +           +  G V+     ++H DP Y+
Sbjct: 356 LDMVVNETLRLFPIAMRLERVCKKDVEI-------NGMFIPKGWVVMIPSYALHRDPKYW 408

Query: 299 EEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVLKC 358
            EPEKF+PERF  +NK  I P+T+ PFG GPR CIG RFALM MK+ L R++ NF    C
Sbjct: 409 TEPEKFLPERFSKKNKDNIDPYTYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPC 468

Query: 359 AKTLDPIKMS 368
            +T  P+K+S
Sbjct: 469 KETQIPLKLS 478



 Score = 74.9 bits (176), Expect = 4e-13
 Identities = 36/92 (39%), Positives = 59/92 (64%), Gaps = 4/92 (4%)

Query: 28  GFTDGVCPGIFIRDPEIIKHVTVKE-FDHFVNNKDLSPEGEESILKNSLIMLKDEKWRKM 86
           GF DG  P + I DP++IK V VKE +  F N +   P G    +K+++ + +DE+W+++
Sbjct: 73  GFYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVG---FMKSAISIAEDEEWKRL 129

Query: 87  RAALSPAFTASKMREMVPLITEISHNIVEYLK 118
           R+ LSP FT+ K++EMVP+I +    +V  L+
Sbjct: 130 RSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLR 161


>J04449-1|AAA35747.1|  502|Homo sapiens cytochrome P450 nifedipine
           oxidase protein.
          Length = 502

 Score =  165 bits (401), Expect = 2e-40
 Identities = 91/250 (36%), Positives = 140/250 (56%), Gaps = 16/250 (6%)

Query: 128 LGFTIIPKSTSEFFRTLIASTVDYRIKNKVERR-DMIQLLM--QLSTEW------TETEL 178
           L   + P+  + F R  +    + R+++  + R D +QL++  Q S E       ++ EL
Sbjct: 235 LNICVFPREVTNFLRKSVKRMKESRLEDTQKHRVDFLQLMIDSQNSKETESHKALSDLEL 294

Query: 179 AAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYENIGELKY 238
            AQ  +F  AG+ETT + L   ++ELA  P +Q  L EE+ A    K    Y+ + +++Y
Sbjct: 295 VAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEY 354

Query: 239 LDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHMDPIYY 298
           LD V+NET+R +  A+ ++R+C K   +           +  G V+     ++H DP Y+
Sbjct: 355 LDMVVNETLRLFPIAMRLERVCKKDVEI-------NGMFIPKGWVVMIPSYALHRDPKYW 407

Query: 299 EEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVLKC 358
            EPEKF+PERF  +NK  I P+T+ PFG GPR CIG RFALM MK+ L R++ NF    C
Sbjct: 408 TEPEKFLPERFSKKNKDNIDPYTYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPC 467

Query: 359 AKTLDPIKMS 368
            +T  P+K+S
Sbjct: 468 KETQIPLKLS 477



 Score = 74.9 bits (176), Expect = 4e-13
 Identities = 36/92 (39%), Positives = 59/92 (64%), Gaps = 4/92 (4%)

Query: 28  GFTDGVCPGIFIRDPEIIKHVTVKE-FDHFVNNKDLSPEGEESILKNSLIMLKDEKWRKM 86
           GF DG  P + I DP++IK V VKE +  F N +   P G    +K+++ + +DE+W+++
Sbjct: 73  GFYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVG---FMKSAISIAEDEEWKRL 129

Query: 87  RAALSPAFTASKMREMVPLITEISHNIVEYLK 118
           R+ LSP FT+ K++EMVP+I +    +V  L+
Sbjct: 130 RSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLR 161


>M18907-1|AAA35745.1|  503|Homo sapiens protein ( Human P450 mRNA
           encoding nifedipine oxidase, complete cds. ).
          Length = 503

 Score =  163 bits (396), Expect = 9e-40
 Identities = 90/250 (36%), Positives = 139/250 (55%), Gaps = 16/250 (6%)

Query: 128 LGFTIIPKSTSEFFRTLIASTVDYRIKNKVERR-DMIQLLM--QLSTEW------TETEL 178
           L   + P+  + F R  +    + R+++  + R D +QL++  Q S E       ++ EL
Sbjct: 236 LNICVFPREVTNFLRKSVKRMKESRLEDTQKHRVDFLQLMIDSQNSKETESHKALSDLEL 295

Query: 179 AAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYENIGELKY 238
            AQ  +F  AG+ETT + L   ++ELA  P +Q  L EE+ A    K    Y+ + +++Y
Sbjct: 296 VAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEY 355

Query: 239 LDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHMDPIYY 298
           LD V+NET+R +  A+ ++R+C K   +           +  G V+     ++H DP Y+
Sbjct: 356 LDMVVNETLRLFPIAMRLERVCKKDVEI-------NGMFIPKGVVVMIPSYALHRDPKYW 408

Query: 299 EEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVLKC 358
            EPEKF+PERF  +NK  I P+ + PFG GPR CIG RFALM MK+ L R++ NF    C
Sbjct: 409 TEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPC 468

Query: 359 AKTLDPIKMS 368
            +T  P+K+S
Sbjct: 469 KETQIPLKLS 478



 Score = 74.9 bits (176), Expect = 4e-13
 Identities = 36/92 (39%), Positives = 59/92 (64%), Gaps = 4/92 (4%)

Query: 28  GFTDGVCPGIFIRDPEIIKHVTVKE-FDHFVNNKDLSPEGEESILKNSLIMLKDEKWRKM 86
           GF DG  P + I DP++IK V VKE +  F N +   P G    +K+++ + +DE+W+++
Sbjct: 73  GFYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVG---FMKSAISIAEDEEWKRL 129

Query: 87  RAALSPAFTASKMREMVPLITEISHNIVEYLK 118
           R+ LSP FT+ K++EMVP+I +    +V  L+
Sbjct: 130 RSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLR 161


>DQ924960-1|ABI96208.1|  503|Homo sapiens cytochrome P450 family 3
           subfamily A polypeptide 4 protein.
          Length = 503

 Score =  163 bits (396), Expect = 9e-40
 Identities = 90/250 (36%), Positives = 139/250 (55%), Gaps = 16/250 (6%)

Query: 128 LGFTIIPKSTSEFFRTLIASTVDYRIKNKVERR-DMIQLLM--QLSTEW------TETEL 178
           L   + P+  + F R  +    + R+++  + R D +QL++  Q S E       ++ EL
Sbjct: 236 LNICVFPREVTNFLRKSVKRMKESRLEDTQKHRVDFLQLMIDSQNSKETESHKALSDLEL 295

Query: 179 AAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYENIGELKY 238
            AQ  +F  AG+ETT + L   ++ELA  P +Q  L EE+ A    K    Y+ + +++Y
Sbjct: 296 VAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEY 355

Query: 239 LDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHMDPIYY 298
           LD V+NET+R +  A+ ++R+C K   +           +  G V+     ++H DP Y+
Sbjct: 356 LDMVVNETLRLFPIAMRLERVCKKDVEI-------NGMFIPKGVVVMIPSYALHRDPKYW 408

Query: 299 EEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVLKC 358
            EPEKF+PERF  +NK  I P+ + PFG GPR CIG RFALM MK+ L R++ NF    C
Sbjct: 409 TEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPC 468

Query: 359 AKTLDPIKMS 368
            +T  P+K+S
Sbjct: 469 KETQIPLKLS 478



 Score = 74.9 bits (176), Expect = 4e-13
 Identities = 36/92 (39%), Positives = 59/92 (64%), Gaps = 4/92 (4%)

Query: 28  GFTDGVCPGIFIRDPEIIKHVTVKE-FDHFVNNKDLSPEGEESILKNSLIMLKDEKWRKM 86
           GF DG  P + I DP++IK V VKE +  F N +   P G    +K+++ + +DE+W+++
Sbjct: 73  GFYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVG---FMKSAISIAEDEEWKRL 129

Query: 87  RAALSPAFTASKMREMVPLITEISHNIVEYLK 118
           R+ LSP FT+ K++EMVP+I +    +V  L+
Sbjct: 130 RSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLR 161


>DQ005611-1|AAY16980.1|  503|Homo sapiens cytochrome P450, family 3,
           subfamily A, polypeptide 4 protein.
          Length = 503

 Score =  163 bits (396), Expect = 9e-40
 Identities = 90/250 (36%), Positives = 139/250 (55%), Gaps = 16/250 (6%)

Query: 128 LGFTIIPKSTSEFFRTLIASTVDYRIKNKVERR-DMIQLLM--QLSTEW------TETEL 178
           L   + P+  + F R  +    + R+++  + R D +QL++  Q S E       ++ EL
Sbjct: 236 LNICVFPREVTNFLRKSVKRMKESRLEDTQKHRVDFLQLMIDSQNSKETESHKALSDLEL 295

Query: 179 AAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYENIGELKY 238
            AQ  +F  AG+ETT + L   ++ELA  P +Q  L EE+ A    K    Y+ + +++Y
Sbjct: 296 VAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEY 355

Query: 239 LDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHMDPIYY 298
           LD V+NET+R +  A+ ++R+C K   +           +  G V+     ++H DP Y+
Sbjct: 356 LDMVVNETLRLFPIAMRLERVCKKDVEI-------NGMFIPKGVVVMIPSYALHRDPKYW 408

Query: 299 EEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVLKC 358
            EPEKF+PERF  +NK  I P+ + PFG GPR CIG RFALM MK+ L R++ NF    C
Sbjct: 409 TEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPC 468

Query: 359 AKTLDPIKMS 368
            +T  P+K+S
Sbjct: 469 KETQIPLKLS 478



 Score = 74.9 bits (176), Expect = 4e-13
 Identities = 36/92 (39%), Positives = 59/92 (64%), Gaps = 4/92 (4%)

Query: 28  GFTDGVCPGIFIRDPEIIKHVTVKE-FDHFVNNKDLSPEGEESILKNSLIMLKDEKWRKM 86
           GF DG  P + I DP++IK V VKE +  F N +   P G    +K+++ + +DE+W+++
Sbjct: 73  GFYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVG---FMKSAISIAEDEEWKRL 129

Query: 87  RAALSPAFTASKMREMVPLITEISHNIVEYLK 118
           R+ LSP FT+ K++EMVP+I +    +V  L+
Sbjct: 130 RSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLR 161


>BC101631-1|AAI01632.1|  503|Homo sapiens cytochrome P450, subfamily
           IIIA, polypeptide 4 protein.
          Length = 503

 Score =  163 bits (396), Expect = 9e-40
 Identities = 90/250 (36%), Positives = 139/250 (55%), Gaps = 16/250 (6%)

Query: 128 LGFTIIPKSTSEFFRTLIASTVDYRIKNKVERR-DMIQLLM--QLSTEW------TETEL 178
           L   + P+  + F R  +    + R+++  + R D +QL++  Q S E       ++ EL
Sbjct: 236 LNICVFPREVTNFLRKSVKRMKESRLEDTQKHRVDFLQLMIDSQNSKETESHKALSDLEL 295

Query: 179 AAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYENIGELKY 238
            AQ  +F  AG+ETT + L   ++ELA  P +Q  L EE+ A    K    Y+ + +++Y
Sbjct: 296 VAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEY 355

Query: 239 LDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHMDPIYY 298
           LD V+NET+R +  A+ ++R+C K   +           +  G V+     ++H DP Y+
Sbjct: 356 LDMVVNETLRLFPIAMRLERVCKKDVEI-------NGMFIPKGVVVMIPSYALHRDPKYW 408

Query: 299 EEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVLKC 358
            EPEKF+PERF  +NK  I P+ + PFG GPR CIG RFALM MK+ L R++ NF    C
Sbjct: 409 TEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPC 468

Query: 359 AKTLDPIKMS 368
            +T  P+K+S
Sbjct: 469 KETQIPLKLS 478



 Score = 74.9 bits (176), Expect = 4e-13
 Identities = 36/92 (39%), Positives = 59/92 (64%), Gaps = 4/92 (4%)

Query: 28  GFTDGVCPGIFIRDPEIIKHVTVKE-FDHFVNNKDLSPEGEESILKNSLIMLKDEKWRKM 86
           GF DG  P + I DP++IK V VKE +  F N +   P G    +K+++ + +DE+W+++
Sbjct: 73  GFYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVG---FMKSAISIAEDEEWKRL 129

Query: 87  RAALSPAFTASKMREMVPLITEISHNIVEYLK 118
           R+ LSP FT+ K++EMVP+I +    +V  L+
Sbjct: 130 RSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLR 161


>BC069418-1|AAH69418.1|  503|Homo sapiens cytochrome P450, family 3,
           subfamily A, polypeptide 4 protein.
          Length = 503

 Score =  163 bits (396), Expect = 9e-40
 Identities = 90/250 (36%), Positives = 139/250 (55%), Gaps = 16/250 (6%)

Query: 128 LGFTIIPKSTSEFFRTLIASTVDYRIKNKVERR-DMIQLLM--QLSTEW------TETEL 178
           L   + P+  + F R  +    + R+++  + R D +QL++  Q S E       ++ EL
Sbjct: 236 LNICVFPREVTNFLRKSVKRMKESRLEDTQKHRVDFLQLMIDSQNSKETESHKALSDLEL 295

Query: 179 AAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYENIGELKY 238
            AQ  +F  AG+ETT + L   ++ELA  P +Q  L EE+ A    K    Y+ + +++Y
Sbjct: 296 VAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEY 355

Query: 239 LDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHMDPIYY 298
           LD V+NET+R +  A+ ++R+C K   +           +  G V+     ++H DP Y+
Sbjct: 356 LDMVVNETLRLFPIAMRLERVCKKDVEI-------NGMFIPKGVVVMIPSYALHRDPKYW 408

Query: 299 EEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVLKC 358
            EPEKF+PERF  +NK  I P+ + PFG GPR CIG RFALM MK+ L R++ NF    C
Sbjct: 409 TEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPC 468

Query: 359 AKTLDPIKMS 368
            +T  P+K+S
Sbjct: 469 KETQIPLKLS 478



 Score = 74.9 bits (176), Expect = 4e-13
 Identities = 36/92 (39%), Positives = 59/92 (64%), Gaps = 4/92 (4%)

Query: 28  GFTDGVCPGIFIRDPEIIKHVTVKE-FDHFVNNKDLSPEGEESILKNSLIMLKDEKWRKM 86
           GF DG  P + I DP++IK V VKE +  F N +   P G    +K+++ + +DE+W+++
Sbjct: 73  GFYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVG---FMKSAISIAEDEEWKRL 129

Query: 87  RAALSPAFTASKMREMVPLITEISHNIVEYLK 118
           R+ LSP FT+ K++EMVP+I +    +V  L+
Sbjct: 130 RSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLR 161


>AJ563377-1|CAD91345.1|  353|Homo sapiens cytochrome P450 protein.
          Length = 353

 Score =  163 bits (396), Expect = 9e-40
 Identities = 90/250 (36%), Positives = 139/250 (55%), Gaps = 16/250 (6%)

Query: 128 LGFTIIPKSTSEFFRTLIASTVDYRIKNKVERR-DMIQLLM--QLSTEW------TETEL 178
           L   + P+  + F R  +    + R+++  + R D +QL++  Q S E       ++ EL
Sbjct: 86  LNICVFPREVTNFLRKSVKRMKESRLEDTQKHRVDFLQLMIDSQNSKETESHKALSDLEL 145

Query: 179 AAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYENIGELKY 238
            AQ  +F  AG+ETT + L   ++ELA  P +Q  L EE+ A    K    Y+ + +++Y
Sbjct: 146 VAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEY 205

Query: 239 LDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHMDPIYY 298
           LD V+NET+R +  A+ ++R+C K   +           +  G V+     ++H DP Y+
Sbjct: 206 LDMVVNETLRLFPIAMRLERVCKKDVEI-------NGMFIPKGVVVMIPSYALHRDPKYW 258

Query: 299 EEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVLKC 358
            EPEKF+PERF  +NK  I P+ + PFG GPR CIG RFALM MK+ L R++ NF    C
Sbjct: 259 TEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPC 318

Query: 359 AKTLDPIKMS 368
            +T  P+K+S
Sbjct: 319 KETQIPLKLS 328


>AJ563376-2|CAD91645.1|  430|Homo sapiens cytochrome P450 protein.
          Length = 430

 Score =  163 bits (396), Expect = 9e-40
 Identities = 90/250 (36%), Positives = 139/250 (55%), Gaps = 16/250 (6%)

Query: 128 LGFTIIPKSTSEFFRTLIASTVDYRIKNKVERR-DMIQLLM--QLSTEW------TETEL 178
           L   + P+  + F R  +    + R+++  + R D +QL++  Q S E       ++ EL
Sbjct: 163 LNICVFPREVTNFLRKSVKRMKESRLEDTQKHRVDFLQLMIDSQNSKETESHKALSDLEL 222

Query: 179 AAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYENIGELKY 238
            AQ  +F  AG+ETT + L   ++ELA  P +Q  L EE+ A    K    Y+ + +++Y
Sbjct: 223 VAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEY 282

Query: 239 LDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHMDPIYY 298
           LD V+NET+R +  A+ ++R+C K   +           +  G V+     ++H DP Y+
Sbjct: 283 LDMVVNETLRLFPIAMRLERVCKKDVEI-------NGMFIPKGVVVMIPSYALHRDPKYW 335

Query: 299 EEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVLKC 358
            EPEKF+PERF  +NK  I P+ + PFG GPR CIG RFALM MK+ L R++ NF    C
Sbjct: 336 TEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPC 395

Query: 359 AKTLDPIKMS 368
            +T  P+K+S
Sbjct: 396 KETQIPLKLS 405



 Score = 72.5 bits (170), Expect = 2e-12
 Identities = 35/91 (38%), Positives = 58/91 (63%), Gaps = 4/91 (4%)

Query: 29  FTDGVCPGIFIRDPEIIKHVTVKE-FDHFVNNKDLSPEGEESILKNSLIMLKDEKWRKMR 87
           F DG  P + I DP++IK V VKE +  F N +   P G    +K+++ + +DE+W+++R
Sbjct: 1   FYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVG---FMKSAISIAEDEEWKRLR 57

Query: 88  AALSPAFTASKMREMVPLITEISHNIVEYLK 118
           + LSP FT+ K++EMVP+I +    +V  L+
Sbjct: 58  SLLSPTFTSGKLKEMVPIIAQYGDVLVRNLR 88


>AJ563375-1|CAD91343.1|  503|Homo sapiens cytochrome P450 protein.
          Length = 503

 Score =  163 bits (396), Expect = 9e-40
 Identities = 90/250 (36%), Positives = 139/250 (55%), Gaps = 16/250 (6%)

Query: 128 LGFTIIPKSTSEFFRTLIASTVDYRIKNKVERR-DMIQLLM--QLSTEW------TETEL 178
           L   + P+  + F R  +    + R+++  + R D +QL++  Q S E       ++ EL
Sbjct: 236 LNICVFPREVTNFLRKSVKRMKESRLEDTQKHRVDFLQLMIDSQNSKETESHKALSDLEL 295

Query: 179 AAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYENIGELKY 238
            AQ  +F  AG+ETT + L   ++ELA  P +Q  L EE+ A    K    Y+ + +++Y
Sbjct: 296 VAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEY 355

Query: 239 LDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHMDPIYY 298
           LD V+NET+R +  A+ ++R+C K   +           +  G V+     ++H DP Y+
Sbjct: 356 LDMVVNETLRLFPIAMRLERVCKKDVEI-------NGMFIPKGVVVMIPSYALHRDPKYW 408

Query: 299 EEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVLKC 358
            EPEKF+PERF  +NK  I P+ + PFG GPR CIG RFALM MK+ L R++ NF    C
Sbjct: 409 TEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPC 468

Query: 359 AKTLDPIKMS 368
            +T  P+K+S
Sbjct: 469 KETQIPLKLS 478



 Score = 74.9 bits (176), Expect = 4e-13
 Identities = 36/92 (39%), Positives = 59/92 (64%), Gaps = 4/92 (4%)

Query: 28  GFTDGVCPGIFIRDPEIIKHVTVKE-FDHFVNNKDLSPEGEESILKNSLIMLKDEKWRKM 86
           GF DG  P + I DP++IK V VKE +  F N +   P G    +K+++ + +DE+W+++
Sbjct: 73  GFYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVG---FMKSAISIAEDEEWKRL 129

Query: 87  RAALSPAFTASKMREMVPLITEISHNIVEYLK 118
           R+ LSP FT+ K++EMVP+I +    +V  L+
Sbjct: 130 RSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLR 161


>AF280107-2|AAG32290.1|  503|Homo sapiens cytochrome P450
           polypeptide 4 protein.
          Length = 503

 Score =  163 bits (396), Expect = 9e-40
 Identities = 90/250 (36%), Positives = 139/250 (55%), Gaps = 16/250 (6%)

Query: 128 LGFTIIPKSTSEFFRTLIASTVDYRIKNKVERR-DMIQLLM--QLSTEW------TETEL 178
           L   + P+  + F R  +    + R+++  + R D +QL++  Q S E       ++ EL
Sbjct: 236 LNICVFPREVTNFLRKSVKRMKESRLEDTQKHRVDFLQLMIDSQNSKETESHKALSDLEL 295

Query: 179 AAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYENIGELKY 238
            AQ  +F  AG+ETT + L   ++ELA  P +Q  L EE+ A    K    Y+ + +++Y
Sbjct: 296 VAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEY 355

Query: 239 LDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHMDPIYY 298
           LD V+NET+R +  A+ ++R+C K   +           +  G V+     ++H DP Y+
Sbjct: 356 LDMVVNETLRLFPIAMRLERVCKKDVEI-------NGMFIPKGVVVMIPSYALHRDPKYW 408

Query: 299 EEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVLKC 358
            EPEKF+PERF  +NK  I P+ + PFG GPR CIG RFALM MK+ L R++ NF    C
Sbjct: 409 TEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPC 468

Query: 359 AKTLDPIKMS 368
            +T  P+K+S
Sbjct: 469 KETQIPLKLS 478



 Score = 74.9 bits (176), Expect = 4e-13
 Identities = 36/92 (39%), Positives = 59/92 (64%), Gaps = 4/92 (4%)

Query: 28  GFTDGVCPGIFIRDPEIIKHVTVKE-FDHFVNNKDLSPEGEESILKNSLIMLKDEKWRKM 86
           GF DG  P + I DP++IK V VKE +  F N +   P G    +K+++ + +DE+W+++
Sbjct: 73  GFYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVG---FMKSAISIAEDEEWKRL 129

Query: 87  RAALSPAFTASKMREMVPLITEISHNIVEYLK 118
           R+ LSP FT+ K++EMVP+I +    +V  L+
Sbjct: 130 RSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLR 161


>AF209389-1|AAF21034.1|  503|Homo sapiens cytochrome P450 IIIA4
           protein.
          Length = 503

 Score =  163 bits (396), Expect = 9e-40
 Identities = 90/250 (36%), Positives = 139/250 (55%), Gaps = 16/250 (6%)

Query: 128 LGFTIIPKSTSEFFRTLIASTVDYRIKNKVERR-DMIQLLM--QLSTEW------TETEL 178
           L   + P+  + F R  +    + R+++  + R D +QL++  Q S E       ++ EL
Sbjct: 236 LNICVFPREVTNFLRKSVKRMKESRLEDTQKHRVDFLQLMIDSQNSKETESHKALSDLEL 295

Query: 179 AAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYENIGELKY 238
            AQ  +F  AG+ETT + L   ++ELA  P +Q  L EE+ A    K    Y+ + +++Y
Sbjct: 296 VAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEY 355

Query: 239 LDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHMDPIYY 298
           LD V+NET+R +  A+ ++R+C K   +           +  G V+     ++H DP Y+
Sbjct: 356 LDMVVNETLRLFPIAMRLERVCKKDVEI-------NGMFIPKGVVVMIPSYALHRDPKYW 408

Query: 299 EEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVLKC 358
            EPEKF+PERF  +NK  I P+ + PFG GPR CIG RFALM MK+ L R++ NF    C
Sbjct: 409 TEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPC 468

Query: 359 AKTLDPIKMS 368
            +T  P+K+S
Sbjct: 469 KETQIPLKLS 478



 Score = 74.9 bits (176), Expect = 4e-13
 Identities = 36/92 (39%), Positives = 59/92 (64%), Gaps = 4/92 (4%)

Query: 28  GFTDGVCPGIFIRDPEIIKHVTVKE-FDHFVNNKDLSPEGEESILKNSLIMLKDEKWRKM 86
           GF DG  P + I DP++IK V VKE +  F N +   P G    +K+++ + +DE+W+++
Sbjct: 73  GFYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVG---FMKSAISIAEDEEWKRL 129

Query: 87  RAALSPAFTASKMREMVPLITEISHNIVEYLK 118
           R+ LSP FT+ K++EMVP+I +    +V  L+
Sbjct: 130 RSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLR 161


>X12387-1|CAA30944.1|  503|Homo sapiens protein ( Human mRNA for
           cytochrome P-450 (cyp3 locus). ).
          Length = 503

 Score =  163 bits (395), Expect = 1e-39
 Identities = 90/250 (36%), Positives = 139/250 (55%), Gaps = 16/250 (6%)

Query: 128 LGFTIIPKSTSEFFRTLIASTVDYRIKNKVERR-DMIQLLM--QLSTEW------TETEL 178
           L   + P+  + F R  +    + R+++  + R D +QL++  Q S E       ++ EL
Sbjct: 236 LNICVFPREVTNFLRKSVKRMKESRLEDTQKHRVDFLQLMIDSQNSKETESHKALSDLEL 295

Query: 179 AAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYENIGELKY 238
            AQ  +F  AG+ETT + L   ++ELA  P +Q  L EE+ A    K    Y+ + +++Y
Sbjct: 296 VAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEY 355

Query: 239 LDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHMDPIYY 298
           LD V+NET+R +  A+ ++R+C K   +           +  G V+     ++H DP Y+
Sbjct: 356 LDMVVNETLRLFPIAMRLERVCKKDVEI-------NGMFIPKGWVVMIPSYALHRDPKYW 408

Query: 299 EEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVLKC 358
            EPEKF+PERF  +NK  I P+ + PFG GPR CIG RFALM MK+ L R++ NF    C
Sbjct: 409 TEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPC 468

Query: 359 AKTLDPIKMS 368
            +T  P+K+S
Sbjct: 469 KETQIPLKLS 478



 Score = 74.9 bits (176), Expect = 4e-13
 Identities = 36/92 (39%), Positives = 59/92 (64%), Gaps = 4/92 (4%)

Query: 28  GFTDGVCPGIFIRDPEIIKHVTVKE-FDHFVNNKDLSPEGEESILKNSLIMLKDEKWRKM 86
           GF DG  P + I DP++IK V VKE +  F N +   P G    +K+++ + +DE+W+++
Sbjct: 73  GFYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVG---FMKSAISIAEDEEWKRL 129

Query: 87  RAALSPAFTASKMREMVPLITEISHNIVEYLK 118
           R+ LSP FT+ K++EMVP+I +    +V  L+
Sbjct: 130 RSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLR 161


>M13785-1|AAA35742.1|  504|Homo sapiens protein ( Human liver
           glucocorticoid-inducible cytochrome P-450 (HLp) mRNA,
           complete cds. ).
          Length = 504

 Score =  163 bits (395), Expect = 1e-39
 Identities = 89/251 (35%), Positives = 136/251 (54%), Gaps = 17/251 (6%)

Query: 128 LGFTIIPKSTSEFFRTLIASTVDYRIKNKVERR-DMIQLLMQLSTEWTETE--------- 177
           L   + P+  + F R  +    + R+++  + R D +QL++       ETE         
Sbjct: 236 LNICVFPREVTNFLRKAVKRMKESRLEDTQKHRVDFLQLMIDSHKNSKETESHKALSDLE 295

Query: 178 LAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYENIGELK 237
           L AQ  +F  AG+ETT + L   ++ELA  P +Q  L EE+ A    K    Y+ + +++
Sbjct: 296 LVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQME 355

Query: 238 YLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHMDPIY 297
           YLD V+NET+R +  A+ ++R+C K   +           +  G V+     ++H DP Y
Sbjct: 356 YLDMVVNETLRLFPIAMRLERVCKKDVEI-------NGMFIPKGWVVMIPSYALHRDPKY 408

Query: 298 YEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVLK 357
           + EPEKF+PERF  +NK  I P+ + PFG GPR CIG RFALM MK+ L R++ NF    
Sbjct: 409 WTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKP 468

Query: 358 CAKTLDPIKMS 368
           C +T  P+K+S
Sbjct: 469 CKETQIPLKLS 479



 Score = 74.1 bits (174), Expect = 8e-13
 Identities = 36/92 (39%), Positives = 59/92 (64%), Gaps = 4/92 (4%)

Query: 28  GFTDGVCPGIFIRDPEIIKHVTVKE-FDHFVNNKDLSPEGEESILKNSLIMLKDEKWRKM 86
           GF DG  P + I DP++IK V VKE +  F N +   P G    +K+++ + +DE+W+++
Sbjct: 73  GFYDGQQPVLAITDPDMIKLVLVKECYSVFTNREPFGPVG---FMKSAISIAEDEEWKRL 129

Query: 87  RAALSPAFTASKMREMVPLITEISHNIVEYLK 118
           R+ LSP FT+ K++EMVP+I +    +V  L+
Sbjct: 130 RSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLR 161


>D00003-1|BAA00001.1|  504|Homo sapiens cytochrome P-450 protein.
          Length = 504

 Score =  163 bits (395), Expect = 1e-39
 Identities = 89/251 (35%), Positives = 136/251 (54%), Gaps = 17/251 (6%)

Query: 128 LGFTIIPKSTSEFFRTLIASTVDYRIKNKVERR-DMIQLLMQLSTEWTETE--------- 177
           L   + P+  + F R  +    + R+++  + R D +QL++       ETE         
Sbjct: 236 LNICVFPREVTNFLRKAVKRMKESRLEDTQKHRVDFLQLMIDSHKNSKETESHKALSDLE 295

Query: 178 LAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYENIGELK 237
           L AQ  +F  AG+ETT + L   ++ELA  P +Q  L EE+ A    K    Y+ + +++
Sbjct: 296 LVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQME 355

Query: 238 YLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHMDPIY 297
           YLD V+NET+R +  A+ ++R+C K   +           +  G V+     ++H DP Y
Sbjct: 356 YLDMVVNETLRLFPIAMRLERVCKKDVEI-------NGMFIPKGWVVMIPSYALHRDPKY 408

Query: 298 YEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVLK 357
           + EPEKF+PERF  +NK  I P+ + PFG GPR CIG RFALM MK+ L R++ NF    
Sbjct: 409 WTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKP 468

Query: 358 CAKTLDPIKMS 368
           C +T  P+K+S
Sbjct: 469 CKETQIPLKLS 479



 Score = 74.1 bits (174), Expect = 8e-13
 Identities = 36/92 (39%), Positives = 59/92 (64%), Gaps = 4/92 (4%)

Query: 28  GFTDGVCPGIFIRDPEIIKHVTVKE-FDHFVNNKDLSPEGEESILKNSLIMLKDEKWRKM 86
           GF DG  P + I DP++IK V VKE +  F N +   P G    +K+++ + +DE+W+++
Sbjct: 73  GFYDGQQPVLAITDPDMIKLVLVKECYSVFTNREPFGPVG---FMKSAISIAEDEEWKRL 129

Query: 87  RAALSPAFTASKMREMVPLITEISHNIVEYLK 118
           R+ LSP FT+ K++EMVP+I +    +V  L+
Sbjct: 130 RSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLR 161


>AF182273-1|AAF13598.1|  503|Homo sapiens cytochrome P450-3A4
           protein.
          Length = 503

 Score =  161 bits (391), Expect = 4e-39
 Identities = 90/250 (36%), Positives = 138/250 (55%), Gaps = 16/250 (6%)

Query: 128 LGFTIIPKSTSEFFRTLIASTVDYRIKNKVERR-DMIQLLM--QLSTEW------TETEL 178
           L   + P+  + F R  +    + R+++  + R D +QL++  Q S E       ++ EL
Sbjct: 236 LNICVFPREVTNFLRKSVKRMKESRLEDTQKHRVDFLQLMIDSQNSKETESHKALSDLEL 295

Query: 179 AAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYENIGELKY 238
            AQ  +F  AG ETT + L   ++ELA  P +Q  L EE+ A    K    Y+ + +++Y
Sbjct: 296 VAQSIIFIFAGCETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEY 355

Query: 239 LDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHMDPIYY 298
           LD V+NET+R +  A+ ++R+C K   +           +  G V+     ++H DP Y+
Sbjct: 356 LDMVVNETLRLFPIAMRLERVCKKDVEI-------NGMFIPKGVVVMIPSYALHRDPKYW 408

Query: 299 EEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVLKC 358
            EPEKF+PERF  +NK  I P+ + PFG GPR CIG RFALM MK+ L R++ NF    C
Sbjct: 409 TEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPC 468

Query: 359 AKTLDPIKMS 368
            +T  P+K+S
Sbjct: 469 KETQIPLKLS 478



 Score = 74.9 bits (176), Expect = 4e-13
 Identities = 36/92 (39%), Positives = 59/92 (64%), Gaps = 4/92 (4%)

Query: 28  GFTDGVCPGIFIRDPEIIKHVTVKE-FDHFVNNKDLSPEGEESILKNSLIMLKDEKWRKM 86
           GF DG  P + I DP++IK V VKE +  F N +   P G    +K+++ + +DE+W+++
Sbjct: 73  GFYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVG---FMKSAISIAEDEEWKRL 129

Query: 87  RAALSPAFTASKMREMVPLITEISHNIVEYLK 118
           R+ LSP FT+ K++EMVP+I +    +V  L+
Sbjct: 130 RSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLR 161


>D00408-1|BAA00310.1|  503|Homo sapiens cytochrome P-450 HFLa
           protein.
          Length = 503

 Score =  155 bits (376), Expect = 3e-37
 Identities = 90/259 (34%), Positives = 140/259 (54%), Gaps = 19/259 (7%)

Query: 121 FPSLS---KKLGFTIIPKSTSEFFRTLIASTVDYRIKNKVERR-DMIQLLMQL-STEWTE 175
           FP L+   + L  T+ P+    F    +    + R+K   + R D +QL++   +++ +E
Sbjct: 226 FPFLTPILEALNITVFPRKVISFLTKSVKQIKEGRLKETQKHRVDFLQLMIDSQNSKDSE 285

Query: 176 T-------ELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNL 228
           T       EL AQ  +F  AG+ETT + L   I+ELA  P +Q  + +E+      K   
Sbjct: 286 THKALSDLELMAQSIIFIFAGYETTSSVLSFIIYELATHPDVQQKVQKEIDTVLPNKAPP 345

Query: 229 VYENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTV 288
            Y+ + +L+YLD V+NET+R +  A+ ++R+C K   +           +  G V+    
Sbjct: 346 TYDTVLQLEYLDMVVNETLRLFPVAMRLERVCKKDVEI-------NGMFIPKGVVVMIPS 398

Query: 289 NSIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFR 348
             +H DP Y+ EPEKF+PERF  +NK  I P+ + PFG GPR CIG RFAL+ MK+ L R
Sbjct: 399 YVLHHDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALVNMKLALVR 458

Query: 349 LMLNFKVLKCAKTLDPIKM 367
           ++ NF    C +T  P+K+
Sbjct: 459 VLQNFSFKPCKETQIPLKL 477



 Score = 70.9 bits (166), Expect = 7e-12
 Identities = 41/118 (34%), Positives = 65/118 (55%), Gaps = 6/118 (5%)

Query: 2   NNLLRRTHLWEDYDVVYKAFPNERYVGFTDGVCPGIFIRDPEIIKHVTVKE-FDHFVNNK 60
           N L  R   W      YK +   +  G  D   P + I DP++IK V VKE +  F N +
Sbjct: 49  NALSFRKGYWTFDMECYKKY--RKVWGIYDCQQPMLAITDPDMIKTVLVKECYSVFTNRR 106

Query: 61  DLSPEGEESILKNSLIMLKDEKWRKMRAALSPAFTASKMREMVPLITEISHNIVEYLK 118
              P G    +KN++ + +DE+W+++R+ LSP FT+ K++EMVP+I +    +V  L+
Sbjct: 107 PFGPVG---FMKNAISIAEDEEWKRIRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLR 161


>BC067436-1|AAH67436.1|  503|Homo sapiens cytochrome P450, family 3,
           subfamily A, polypeptide 7 protein.
          Length = 503

 Score =  155 bits (376), Expect = 3e-37
 Identities = 90/259 (34%), Positives = 140/259 (54%), Gaps = 19/259 (7%)

Query: 121 FPSLS---KKLGFTIIPKSTSEFFRTLIASTVDYRIKNKVERR-DMIQLLMQL-STEWTE 175
           FP L+   + L  T+ P+    F    +    + R+K   + R D +QL++   +++ +E
Sbjct: 226 FPFLTPILEALNITVFPRKVISFLTKSVKQIKEGRLKETQKHRVDFLQLMIDSQNSKDSE 285

Query: 176 T-------ELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNL 228
           T       EL AQ  +F  AG+ETT + L   I+ELA  P +Q  + +E+      K   
Sbjct: 286 THKALSDLELMAQSIIFIFAGYETTSSVLSFIIYELATHPDVQQKVQKEIDTVLPNKAPP 345

Query: 229 VYENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTV 288
            Y+ + +L+YLD V+NET+R +  A+ ++R+C K   +           +  G V+    
Sbjct: 346 TYDTVLQLEYLDMVVNETLRLFPVAMRLERVCKKDVEI-------NGMFIPKGVVVMIPS 398

Query: 289 NSIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFR 348
             +H DP Y+ EPEKF+PERF  +NK  I P+ + PFG GPR CIG RFAL+ MK+ L R
Sbjct: 399 YVLHHDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALVNMKLALVR 458

Query: 349 LMLNFKVLKCAKTLDPIKM 367
           ++ NF    C +T  P+K+
Sbjct: 459 VLQNFSFKPCKETQIPLKL 477



 Score = 70.9 bits (166), Expect = 7e-12
 Identities = 41/118 (34%), Positives = 65/118 (55%), Gaps = 6/118 (5%)

Query: 2   NNLLRRTHLWEDYDVVYKAFPNERYVGFTDGVCPGIFIRDPEIIKHVTVKE-FDHFVNNK 60
           N L  R   W      YK +   +  G  D   P + I DP++IK V VKE +  F N +
Sbjct: 49  NALSFRKGYWTFDMECYKKY--RKVWGIYDCQQPMLAITDPDMIKTVLVKECYSVFTNRR 106

Query: 61  DLSPEGEESILKNSLIMLKDEKWRKMRAALSPAFTASKMREMVPLITEISHNIVEYLK 118
              P G    +KN++ + +DE+W+++R+ LSP FT+ K++EMVP+I +    +V  L+
Sbjct: 107 PFGPVG---FMKNAISIAEDEEWKRIRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLR 161


>AF315325-1|AAG48618.1|  535|Homo sapiens cytochrome P450 variant
           3A7 protein.
          Length = 535

 Score =  155 bits (376), Expect = 3e-37
 Identities = 90/259 (34%), Positives = 140/259 (54%), Gaps = 19/259 (7%)

Query: 121 FPSLS---KKLGFTIIPKSTSEFFRTLIASTVDYRIKNKVERR-DMIQLLMQL-STEWTE 175
           FP L+   + L  T+ P+    F    +    + R+K   + R D +QL++   +++ +E
Sbjct: 226 FPFLTPILEALNITVFPRKVISFLTKSVKQIKEGRLKETQKHRVDFLQLMIDSQNSKDSE 285

Query: 176 T-------ELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNL 228
           T       EL AQ  +F  AG+ETT + L   I+ELA  P +Q  + +E+      K   
Sbjct: 286 THKALSDLELMAQSIIFIFAGYETTSSVLSFIIYELATHPDVQQKVQKEIDTVLPNKAPP 345

Query: 229 VYENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTV 288
            Y+ + +L+YLD V+NET+R +  A+ ++R+C K   +           +  G V+    
Sbjct: 346 TYDTVLQLEYLDMVVNETLRLFPVAMRLERVCKKDVEI-------NGMFIPKGVVVMIPS 398

Query: 289 NSIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFR 348
             +H DP Y+ EPEKF+PERF  +NK  I P+ + PFG GPR CIG RFAL+ MK+ L R
Sbjct: 399 YVLHHDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALVNMKLALVR 458

Query: 349 LMLNFKVLKCAKTLDPIKM 367
           ++ NF    C +T  P+K+
Sbjct: 459 VLQNFSFKPCKETQIPLKL 477



 Score = 70.9 bits (166), Expect = 7e-12
 Identities = 41/118 (34%), Positives = 65/118 (55%), Gaps = 6/118 (5%)

Query: 2   NNLLRRTHLWEDYDVVYKAFPNERYVGFTDGVCPGIFIRDPEIIKHVTVKE-FDHFVNNK 60
           N L  R   W      YK +   +  G  D   P + I DP++IK V VKE +  F N +
Sbjct: 49  NALSFRKGYWTFDMECYKKY--RKVWGIYDCQQPMLAITDPDMIKTVLVKECYSVFTNRR 106

Query: 61  DLSPEGEESILKNSLIMLKDEKWRKMRAALSPAFTASKMREMVPLITEISHNIVEYLK 118
              P G    +KN++ + +DE+W+++R+ LSP FT+ K++EMVP+I +    +V  L+
Sbjct: 107 PFGPVG---FMKNAISIAEDEEWKRIRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLR 161


>AF280107-3|AAG32289.1|  503|Homo sapiens cytochrome P450
           polypeptide 7 protein.
          Length = 503

 Score =  155 bits (376), Expect = 3e-37
 Identities = 90/259 (34%), Positives = 140/259 (54%), Gaps = 19/259 (7%)

Query: 121 FPSLS---KKLGFTIIPKSTSEFFRTLIASTVDYRIKNKVERR-DMIQLLMQL-STEWTE 175
           FP L+   + L  T+ P+    F    +    + R+K   + R D +QL++   +++ +E
Sbjct: 226 FPFLTPILEALNITVFPRKVISFLTKSVKQIKEGRLKETQKHRVDFLQLMIDSQNSKDSE 285

Query: 176 T-------ELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNL 228
           T       EL AQ  +F  AG+ETT + L   I+ELA  P +Q  + +E+      K   
Sbjct: 286 THKALSDLELMAQSIIFIFAGYETTSSVLSFIIYELATHPDVQQKVQKEIDTVLPNKAPP 345

Query: 229 VYENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTV 288
            Y+ + +L+YLD V+NET+R +  A+ ++R+C K   +           +  G V+    
Sbjct: 346 TYDTVLQLEYLDMVVNETLRLFPVAMRLERVCKKDVEI-------NGMFIPKGVVVMIPS 398

Query: 289 NSIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFR 348
             +H DP Y+ EPEKF+PERF  +NK  I P+ + PFG GPR CIG RFAL+ MK+ L R
Sbjct: 399 YVLHHDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALVNMKLALVR 458

Query: 349 LMLNFKVLKCAKTLDPIKM 367
           ++ NF    C +T  P+K+
Sbjct: 459 VLQNFSFKPCKETQIPLKL 477



 Score = 70.9 bits (166), Expect = 7e-12
 Identities = 41/118 (34%), Positives = 65/118 (55%), Gaps = 6/118 (5%)

Query: 2   NNLLRRTHLWEDYDVVYKAFPNERYVGFTDGVCPGIFIRDPEIIKHVTVKE-FDHFVNNK 60
           N L  R   W      YK +   +  G  D   P + I DP++IK V VKE +  F N +
Sbjct: 49  NALSFRKGYWTFDMECYKKY--RKVWGIYDCQQPMLAITDPDMIKTVLVKECYSVFTNRR 106

Query: 61  DLSPEGEESILKNSLIMLKDEKWRKMRAALSPAFTASKMREMVPLITEISHNIVEYLK 118
              P G    +KN++ + +DE+W+++R+ LSP FT+ K++EMVP+I +    +V  L+
Sbjct: 107 PFGPVG---FMKNAISIAEDEEWKRIRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLR 161


>J04813-1|AAA02993.1|  502|Homo sapiens cytochrome P450 PCN3
           protein.
          Length = 502

 Score =  155 bits (375), Expect = 3e-37
 Identities = 93/263 (35%), Positives = 141/263 (53%), Gaps = 20/263 (7%)

Query: 121 FPSLS---KKLGFTIIPKSTSEFFRTLIASTVDYRIKNKVERR-DMIQLLM--QLSTEW- 173
           FP L+   + L  ++ PK T  F    +      R+ +K + R D +QL++  Q S E  
Sbjct: 226 FPFLTPVFEALNVSLFPKDTINFLSKSVNRMKKSRLNDKQKHRLDFLQLMIDSQNSKETE 285

Query: 174 -----TETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNL 228
                ++ ELAAQ  +F  AG+ETT + L   ++ELA  P +Q  L +E+ A    K   
Sbjct: 286 SHKALSDLELAAQSIIFIFAGYETTSSVLSFTLYELATHPDVQQKLQKEIDAVLPNKAPP 345

Query: 229 VYENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTV 288
            Y+ + +++YLD V+NET+R +  AI ++R C K   +           +  G ++    
Sbjct: 346 TYDAVVQMEYLDMVVNETLRLFPVAIRLERTCKKDVEI-------NGVFIPKGSMVVIPT 398

Query: 289 NSIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFR 348
            ++H DP Y+ EPE+F PERF  + K  I P+ + PFG GPR CIG RFALM MK+ L R
Sbjct: 399 YALHHDPKYWTEPEEFRPERF-SKKKDSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIR 457

Query: 349 LMLNFKVLKCAKTLDPIKMSPVG 371
           ++ NF    C +T  P+K+   G
Sbjct: 458 VLQNFSFKPCKETQIPLKLDTQG 480



 Score = 73.7 bits (173), Expect = 1e-12
 Identities = 40/118 (33%), Positives = 68/118 (57%), Gaps = 6/118 (5%)

Query: 2   NNLLRRTHLWEDYDVVYKAFPNERYVGFTDGVCPGIFIRDPEIIKHVTVKE-FDHFVNNK 60
           N L  R  LW+     YK +   +  G  +G  P + I DP++I+ V VKE +  F N +
Sbjct: 49  NVLSYRQGLWKFDTECYKKYG--KMWGTYEGQLPVLAITDPDVIRTVLVKECYSVFTNRR 106

Query: 61  DLSPEGEESILKNSLIMLKDEKWRKMRAALSPAFTASKMREMVPLITEISHNIVEYLK 118
            L P G    +K+++ + +DE+W+++R+ LSP FT+ K++EM P+I +    +V  L+
Sbjct: 107 SLGPVG---FMKSAISLAEDEEWKRIRSLLSPTFTSGKLKEMFPIIAQYGDVLVRNLR 161


>BC033862-1|AAH33862.1|  502|Homo sapiens cytochrome P450, family 3,
           subfamily A, polypeptide 5 protein.
          Length = 502

 Score =  155 bits (375), Expect = 3e-37
 Identities = 93/263 (35%), Positives = 141/263 (53%), Gaps = 20/263 (7%)

Query: 121 FPSLS---KKLGFTIIPKSTSEFFRTLIASTVDYRIKNKVERR-DMIQLLM--QLSTEW- 173
           FP L+   + L  ++ PK T  F    +      R+ +K + R D +QL++  Q S E  
Sbjct: 226 FPFLTPVFEALNVSLFPKDTINFLSKSVNRMKKSRLNDKQKHRLDFLQLMIDSQNSKETE 285

Query: 174 -----TETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNL 228
                ++ ELAAQ  +F  AG+ETT + L   ++ELA  P +Q  L +E+ A    K   
Sbjct: 286 SHKALSDLELAAQSIIFIFAGYETTSSVLSFTLYELATHPDVQQKLQKEIDAVLPNKAPP 345

Query: 229 VYENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTV 288
            Y+ + +++YLD V+NET+R +  AI ++R C K   +           +  G ++    
Sbjct: 346 TYDAVVQMEYLDMVVNETLRLFPVAIRLERTCKKDVEI-------NGVFIPKGSMVVIPT 398

Query: 289 NSIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFR 348
            ++H DP Y+ EPE+F PERF  + K  I P+ + PFG GPR CIG RFALM MK+ L R
Sbjct: 399 YALHHDPKYWTEPEEFRPERF-SKKKDSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIR 457

Query: 349 LMLNFKVLKCAKTLDPIKMSPVG 371
           ++ NF    C +T  P+K+   G
Sbjct: 458 VLQNFSFKPCKETQIPLKLDTQG 480



 Score = 73.7 bits (173), Expect = 1e-12
 Identities = 40/118 (33%), Positives = 68/118 (57%), Gaps = 6/118 (5%)

Query: 2   NNLLRRTHLWEDYDVVYKAFPNERYVGFTDGVCPGIFIRDPEIIKHVTVKE-FDHFVNNK 60
           N L  R  LW+     YK +   +  G  +G  P + I DP++I+ V VKE +  F N +
Sbjct: 49  NVLSYRQGLWKFDTECYKKYG--KMWGTYEGQLPVLAITDPDVIRTVLVKECYSVFTNRR 106

Query: 61  DLSPEGEESILKNSLIMLKDEKWRKMRAALSPAFTASKMREMVPLITEISHNIVEYLK 118
            L P G    +K+++ + +DE+W+++R+ LSP FT+ K++EM P+I +    +V  L+
Sbjct: 107 SLGPVG---FMKSAISLAEDEEWKRIRSLLSPTFTSGKLKEMFPIIAQYGDVLVRNLR 161


>AK223008-1|BAD96728.1|  502|Homo sapiens cytochrome P450, family 3,
           subfamily A, polypeptide 5 variant protein.
          Length = 502

 Score =  155 bits (375), Expect = 3e-37
 Identities = 93/263 (35%), Positives = 141/263 (53%), Gaps = 20/263 (7%)

Query: 121 FPSLS---KKLGFTIIPKSTSEFFRTLIASTVDYRIKNKVERR-DMIQLLM--QLSTEW- 173
           FP L+   + L  ++ PK T  F    +      R+ +K + R D +QL++  Q S E  
Sbjct: 226 FPFLTPVFEALNVSLFPKDTINFLSKSVNRMKKSRLNDKQKHRLDFLQLMIDSQNSKETE 285

Query: 174 -----TETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNL 228
                ++ ELAAQ  +F  AG+ETT + L   ++ELA  P +Q  L +E+ A    K   
Sbjct: 286 SHKALSDLELAAQSIIFIFAGYETTSSVLSFTLYELATHPDVQQKLQKEIDAVLPNKAPP 345

Query: 229 VYENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTV 288
            Y+ + +++YLD V+NET+R +  AI ++R C K   +           +  G ++    
Sbjct: 346 TYDAVVQMEYLDMVVNETLRLFPVAIRLERTCMKDVEI-------NGVFIPKGSMVVIPT 398

Query: 289 NSIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFR 348
            ++H DP Y+ EPE+F PERF  + K  I P+ + PFG GPR CIG RFALM MK+ L R
Sbjct: 399 YALHHDPKYWTEPEEFRPERF-SKKKDSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIR 457

Query: 349 LMLNFKVLKCAKTLDPIKMSPVG 371
           ++ NF    C +T  P+K+   G
Sbjct: 458 VLQNFSFKPCKETQIPLKLDTQG 480



 Score = 72.9 bits (171), Expect = 2e-12
 Identities = 40/118 (33%), Positives = 67/118 (56%), Gaps = 6/118 (5%)

Query: 2   NNLLRRTHLWEDYDVVYKAFPNERYVGFTDGVCPGIFIRDPEIIKHVTVKE-FDHFVNNK 60
           N L  R  LW+     YK +   +  G  +G  P + I DP++I+ V VKE +  F N +
Sbjct: 49  NVLSYRQGLWKFDTECYKKYG--KMWGTYEGQLPVLAITDPDVIRTVLVKECYSVFTNRR 106

Query: 61  DLSPEGEESILKNSLIMLKDEKWRKMRAALSPAFTASKMREMVPLITEISHNIVEYLK 118
            L P G    +K+++ + +DE+W+++R  LSP FT+ K++EM P+I +    +V  L+
Sbjct: 107 SLGPVG---FMKSAISLAEDEEWKRIRPLLSPTFTSGKLKEMFPIIAQYGDVLVRNLR 161


>AC005020-1|AAS02016.1|  502|Homo sapiens unknown protein.
          Length = 502

 Score =  155 bits (375), Expect = 3e-37
 Identities = 93/263 (35%), Positives = 141/263 (53%), Gaps = 20/263 (7%)

Query: 121 FPSLS---KKLGFTIIPKSTSEFFRTLIASTVDYRIKNKVERR-DMIQLLM--QLSTEW- 173
           FP L+   + L  ++ PK T  F    +      R+ +K + R D +QL++  Q S E  
Sbjct: 226 FPFLTPVFEALNVSLFPKDTINFLSKSVNRMKKSRLNDKQKHRLDFLQLMIDSQNSKETE 285

Query: 174 -----TETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNL 228
                ++ ELAAQ  +F  AG+ETT + L   ++ELA  P +Q  L +E+ A    K   
Sbjct: 286 SHKALSDLELAAQSIIFIFAGYETTSSVLSFTLYELATHPDVQQKLQKEIDAVLPNKAPP 345

Query: 229 VYENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTV 288
            Y+ + +++YLD V+NET+R +  AI ++R C K   +           +  G ++    
Sbjct: 346 TYDAVVQMEYLDMVVNETLRLFPVAIRLERTCKKDVEI-------NGVFIPKGSMVVIPT 398

Query: 289 NSIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFR 348
            ++H DP Y+ EPE+F PERF  + K  I P+ + PFG GPR CIG RFALM MK+ L R
Sbjct: 399 YALHHDPKYWTEPEEFRPERF-SKKKDSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIR 457

Query: 349 LMLNFKVLKCAKTLDPIKMSPVG 371
           ++ NF    C +T  P+K+   G
Sbjct: 458 VLQNFSFKPCKETQIPLKLDTQG 480



 Score = 73.7 bits (173), Expect = 1e-12
 Identities = 40/118 (33%), Positives = 68/118 (57%), Gaps = 6/118 (5%)

Query: 2   NNLLRRTHLWEDYDVVYKAFPNERYVGFTDGVCPGIFIRDPEIIKHVTVKE-FDHFVNNK 60
           N L  R  LW+     YK +   +  G  +G  P + I DP++I+ V VKE +  F N +
Sbjct: 49  NVLSYRQGLWKFDTECYKKYG--KMWGTYEGQLPVLAITDPDVIRTVLVKECYSVFTNRR 106

Query: 61  DLSPEGEESILKNSLIMLKDEKWRKMRAALSPAFTASKMREMVPLITEISHNIVEYLK 118
            L P G    +K+++ + +DE+W+++R+ LSP FT+ K++EM P+I +    +V  L+
Sbjct: 107 SLGPVG---FMKSAISLAEDEEWKRIRSLLSPTFTSGKLKEMFPIIAQYGDVLVRNLR 161


>BC100981-1|AAI00982.1|  393|Homo sapiens CYP3A43 protein protein.
          Length = 393

 Score =  148 bits (359), Expect = 3e-35
 Identities = 97/295 (32%), Positives = 150/295 (50%), Gaps = 21/295 (7%)

Query: 82  KWRKMRAALSPAFTASKMREMVPLITEISHNIVEYLKDHFPSLSKKLGFTIIPKSTSEFF 141
           K R  R AL P +    + E V   TE    +  +L   F +L+  +G  + PK  + F 
Sbjct: 85  KVRSSRPAL-PTWVFGILTENVMKNTEKCGALFPFLTPVFEALN--IG--LFPKDVTHFL 139

Query: 142 RTLIASTVDYRIKNKVERR-DMIQLLM--QLSTEW------TETELAAQLFVFFVAGFET 192
           +  I    + R+K+K + R D  Q ++  Q S E       ++ EL AQ  +   A ++T
Sbjct: 140 KNSIERMKESRLKDKQKHRVDFFQQMIDSQNSKETKSHKALSDLELVAQSIIIIFAAYDT 199

Query: 193 TGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYENIGELKYLDCVLNETMRKWSA 252
           T  TL   ++ELA  P +Q  L EE+ A    K  + Y+ + +++YLD V+NET+R +  
Sbjct: 200 TSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAPVTYDALVQMEYLDMVVNETLRLFPV 259

Query: 253 AIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHMDPIYYEEPEKFIPERFLDE 312
              V R+C K   +           +  G  +   + ++H DP Y+ EPEKF PERF  +
Sbjct: 260 VSRVTRVCKKDIEI-------NGVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPERFSKK 312

Query: 313 NKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVLKCAKTLDPIKM 367
           NK  I  + ++PFG GPR CIG RFAL  +K+ + R + NF    C +T  P+K+
Sbjct: 313 NKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSFKPCKETQIPLKL 367


>AY390425-1|AAQ92353.1|  503|Homo sapiens cytochrome P450 CYP3A43.1
           protein.
          Length = 503

 Score =  146 bits (354), Expect = 1e-34
 Identities = 87/259 (33%), Positives = 135/259 (52%), Gaps = 19/259 (7%)

Query: 121 FPSLS---KKLGFTIIPKSTSEFFRTLIASTVDYRIKNKVERR-DMIQLLM--QLSTEW- 173
           FP L+   + L   + PK  + F +  I    + R+K+K + R D  Q ++  Q S E  
Sbjct: 226 FPFLTPVFEALNIGLFPKDVTHFLKNSIERMKESRLKDKQKHRVDFFQQMIDSQNSKETK 285

Query: 174 -----TETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNL 228
                ++ EL AQ  +   A ++TT  TL   ++ELA  P +Q  L EE+ A    K  +
Sbjct: 286 SHKALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAPV 345

Query: 229 VYENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTV 288
            Y+ + +++YLD V+NET+R +     V R+C K   +           +  G  +   +
Sbjct: 346 TYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEI-------NGVFIPKGLAVMVPI 398

Query: 289 NSIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFR 348
            ++H DP Y+ EPEKF PERF  +NK  I  + ++PFG GPR CIG RFAL  +K+ + R
Sbjct: 399 YALHHDPKYWTEPEKFCPERFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIR 458

Query: 349 LMLNFKVLKCAKTLDPIKM 367
            + NF    C +T  P+K+
Sbjct: 459 ALQNFSFKPCKETQIPLKL 477



 Score = 73.7 bits (173), Expect = 1e-12
 Identities = 41/100 (41%), Positives = 61/100 (61%), Gaps = 7/100 (7%)

Query: 23  NERYV---GFTDGVCPGIFIRDPEIIKHVTVKE-FDHFVNNKDLSPEGEESILKNSLIML 78
           NE+Y    G  +G  P + I DP++IK V VKE +  F N   L P G    LK++L   
Sbjct: 65  NEKYGEMWGLYEGQQPMLVIMDPDMIKTVLVKECYSVFTNQMPLGPMG---FLKSALSFA 121

Query: 79  KDEKWRKMRAALSPAFTASKMREMVPLITEISHNIVEYLK 118
           +DE+W+++R  LSPAFT+ K +EMVP+I++    +V  L+
Sbjct: 122 EDEEWKRIRTLLSPAFTSVKFKEMVPIISQCGDMLVRSLR 161


>AY390424-1|AAQ92352.1|  503|Homo sapiens cytochrome P450 CYP3A43.3
           protein.
          Length = 503

 Score =  146 bits (354), Expect = 1e-34
 Identities = 87/259 (33%), Positives = 135/259 (52%), Gaps = 19/259 (7%)

Query: 121 FPSLS---KKLGFTIIPKSTSEFFRTLIASTVDYRIKNKVERR-DMIQLLM--QLSTEW- 173
           FP L+   + L   + PK  + F +  I    + R+K+K + R D  Q ++  Q S E  
Sbjct: 226 FPFLTPVFEALNIGLFPKDVTHFLKNSIERMKESRLKDKQKHRVDFFQQMIDSQNSKETK 285

Query: 174 -----TETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNL 228
                ++ EL AQ  +   A ++TT  TL   ++ELA  P +Q  L EE+ A    K  +
Sbjct: 286 SHKALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLANKAPV 345

Query: 229 VYENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTV 288
            Y+ + +++YLD V+NET+R +     V R+C K   +           +  G  +   +
Sbjct: 346 TYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEI-------NGVFIPKGLAVMVPI 398

Query: 289 NSIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFR 348
            ++H DP Y+ EPEKF PERF  +NK  I  + ++PFG GPR CIG RFAL  +K+ + R
Sbjct: 399 YALHHDPKYWTEPEKFCPERFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIR 458

Query: 349 LMLNFKVLKCAKTLDPIKM 367
            + NF    C +T  P+K+
Sbjct: 459 ALQNFSFKPCKETQIPLKL 477



 Score = 73.7 bits (173), Expect = 1e-12
 Identities = 41/100 (41%), Positives = 61/100 (61%), Gaps = 7/100 (7%)

Query: 23  NERYV---GFTDGVCPGIFIRDPEIIKHVTVKE-FDHFVNNKDLSPEGEESILKNSLIML 78
           NE+Y    G  +G  P + I DP++IK V VKE +  F N   L P G    LK++L   
Sbjct: 65  NEKYGEMWGLYEGQQPMLVIMDPDMIKTVLVKECYSVFTNQMPLGPMG---FLKSALSFA 121

Query: 79  KDEKWRKMRAALSPAFTASKMREMVPLITEISHNIVEYLK 118
           +DE+W+++R  LSPAFT+ K +EMVP+I++    +V  L+
Sbjct: 122 EDEEWKRIRTLLSPAFTSVKFKEMVPIISQCGDMLVRSLR 161


>AF337813-1|AAK38841.1|  503|Homo sapiens cytochrome P450 subfamily
           IIIA polypeptide 43 protein.
          Length = 503

 Score =  146 bits (354), Expect = 1e-34
 Identities = 87/259 (33%), Positives = 135/259 (52%), Gaps = 19/259 (7%)

Query: 121 FPSLS---KKLGFTIIPKSTSEFFRTLIASTVDYRIKNKVERR-DMIQLLM--QLSTEW- 173
           FP L+   + L   + PK  + F +  I    + R+K+K + R D  Q ++  Q S E  
Sbjct: 226 FPFLTPVFEALNIGLFPKDVTHFLKNSIERMKESRLKDKQKHRVDFFQQMIDSQNSKETK 285

Query: 174 -----TETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNL 228
                ++ EL AQ  +   A ++TT  TL   ++ELA  P +Q  L EE+ A    K  +
Sbjct: 286 SHKALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAPV 345

Query: 229 VYENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTV 288
            Y+ + +++YLD V+NET+R +     V R+C K   +           +  G  +   +
Sbjct: 346 TYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEI-------NGVFIPKGLAVMVPI 398

Query: 289 NSIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFR 348
            ++H DP Y+ EPEKF PERF  +NK  I  + ++PFG GPR CIG RFAL  +K+ + R
Sbjct: 399 YALHHDPKYWTEPEKFCPERFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIR 458

Query: 349 LMLNFKVLKCAKTLDPIKM 367
            + NF    C +T  P+K+
Sbjct: 459 ALQNFSFKPCKETQIPLKL 477



 Score = 73.7 bits (173), Expect = 1e-12
 Identities = 41/100 (41%), Positives = 61/100 (61%), Gaps = 7/100 (7%)

Query: 23  NERYV---GFTDGVCPGIFIRDPEIIKHVTVKE-FDHFVNNKDLSPEGEESILKNSLIML 78
           NE+Y    G  +G  P + I DP++IK V VKE +  F N   L P G    LK++L   
Sbjct: 65  NEKYGEMWGLYEGQQPMLVIMDPDMIKTVLVKECYSVFTNQMPLGPMG---FLKSALSFA 121

Query: 79  KDEKWRKMRAALSPAFTASKMREMVPLITEISHNIVEYLK 118
           +DE+W+++R  LSPAFT+ K +EMVP+I++    +V  L+
Sbjct: 122 EDEEWKRIRTLLSPAFTSVKFKEMVPIISQCGDMLVRSLR 161


>AF319634-1|AAK00325.1|  503|Homo sapiens cytochrome P450 CYP3A43
           protein.
          Length = 503

 Score =  146 bits (354), Expect = 1e-34
 Identities = 87/259 (33%), Positives = 135/259 (52%), Gaps = 19/259 (7%)

Query: 121 FPSLS---KKLGFTIIPKSTSEFFRTLIASTVDYRIKNKVERR-DMIQLLM--QLSTEW- 173
           FP L+   + L   + PK  + F +  I    + R+K+K + R D  Q ++  Q S E  
Sbjct: 226 FPFLTPVFEALNIGLFPKDVTHFLKNSIERMKESRLKDKQKHRVDFFQQMIDSQNSKETK 285

Query: 174 -----TETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNL 228
                ++ EL AQ  +   A ++TT  TL   ++ELA  P +Q  L EE+ A    K  +
Sbjct: 286 SHKALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAPV 345

Query: 229 VYENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTV 288
            Y+ + +++YLD V+NET+R +     V R+C K   +           +  G  +   +
Sbjct: 346 TYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEI-------NGVFIPKGLAVMVPI 398

Query: 289 NSIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFR 348
            ++H DP Y+ EPEKF PERF  +NK  I  + ++PFG GPR CIG RFAL  +K+ + R
Sbjct: 399 YALHHDPKYWTEPEKFCPERFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIR 458

Query: 349 LMLNFKVLKCAKTLDPIKM 367
            + NF    C +T  P+K+
Sbjct: 459 ALQNFSFKPCKETQIPLKL 477



 Score = 73.7 bits (173), Expect = 1e-12
 Identities = 41/100 (41%), Positives = 61/100 (61%), Gaps = 7/100 (7%)

Query: 23  NERYV---GFTDGVCPGIFIRDPEIIKHVTVKE-FDHFVNNKDLSPEGEESILKNSLIML 78
           NE+Y    G  +G  P + I DP++IK V VKE +  F N   L P G    LK++L   
Sbjct: 65  NEKYGEMWGLYEGQQPMLVIMDPDMIKTVLVKECYSVFTNQMPLGPMG---FLKSALSFA 121

Query: 79  KDEKWRKMRAALSPAFTASKMREMVPLITEISHNIVEYLK 118
           +DE+W+++R  LSPAFT+ K +EMVP+I++    +V  L+
Sbjct: 122 EDEEWKRIRTLLSPAFTSVKFKEMVPIISQCGDMLVRSLR 161


>AF280108-1|AAG33009.1|  503|Homo sapiens cytochrome P450 subfamily
           IIIA polypeptide 43 protein.
          Length = 503

 Score =  146 bits (354), Expect = 1e-34
 Identities = 87/259 (33%), Positives = 135/259 (52%), Gaps = 19/259 (7%)

Query: 121 FPSLS---KKLGFTIIPKSTSEFFRTLIASTVDYRIKNKVERR-DMIQLLM--QLSTEW- 173
           FP L+   + L   + PK  + F +  I    + R+K+K + R D  Q ++  Q S E  
Sbjct: 226 FPFLTPVFEALNIGLFPKDVTHFLKNSIERMKESRLKDKQKHRVDFFQQMIDSQNSKETK 285

Query: 174 -----TETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNL 228
                ++ EL AQ  +   A ++TT  TL   ++ELA  P +Q  L EE+ A    K  +
Sbjct: 286 SHKALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAPV 345

Query: 229 VYENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTV 288
            Y+ + +++YLD V+NET+R +     V R+C K   +           +  G  +   +
Sbjct: 346 TYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEI-------NGVFIPKGLAVMVPI 398

Query: 289 NSIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFR 348
            ++H DP Y+ EPEKF PERF  +NK  I  + ++PFG GPR CIG RFAL  +K+ + R
Sbjct: 399 YALHHDPKYWTEPEKFCPERFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIR 458

Query: 349 LMLNFKVLKCAKTLDPIKM 367
            + NF    C +T  P+K+
Sbjct: 459 ALQNFSFKPCKETQIPLKL 477



 Score = 73.7 bits (173), Expect = 1e-12
 Identities = 41/100 (41%), Positives = 61/100 (61%), Gaps = 7/100 (7%)

Query: 23  NERYV---GFTDGVCPGIFIRDPEIIKHVTVKE-FDHFVNNKDLSPEGEESILKNSLIML 78
           NE+Y    G  +G  P + I DP++IK V VKE +  F N   L P G    LK++L   
Sbjct: 65  NEKYGEMWGLYEGQQPMLVIMDPDMIKTVLVKECYSVFTNQMPLGPMG---FLKSALSFA 121

Query: 79  KDEKWRKMRAALSPAFTASKMREMVPLITEISHNIVEYLK 118
           +DE+W+++R  LSPAFT+ K +EMVP+I++    +V  L+
Sbjct: 122 EDEEWKRIRTLLSPAFTSVKFKEMVPIISQCGDMLVRSLR 161


>AC011904-4|AAS07395.1|  503|Homo sapiens unknown protein.
          Length = 503

 Score =  146 bits (354), Expect = 1e-34
 Identities = 87/259 (33%), Positives = 135/259 (52%), Gaps = 19/259 (7%)

Query: 121 FPSLS---KKLGFTIIPKSTSEFFRTLIASTVDYRIKNKVERR-DMIQLLM--QLSTEW- 173
           FP L+   + L   + PK  + F +  I    + R+K+K + R D  Q ++  Q S E  
Sbjct: 226 FPFLTPVFEALNIGLFPKDVTHFLKNSIERMKESRLKDKQKHRVDFFQQMIDSQNSKETK 285

Query: 174 -----TETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNL 228
                ++ EL AQ  +   A ++TT  TL   ++ELA  P +Q  L EE+ A    K  +
Sbjct: 286 SHKALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAPV 345

Query: 229 VYENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTV 288
            Y+ + +++YLD V+NET+R +     V R+C K   +           +  G  +   +
Sbjct: 346 TYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEI-------NGVFIPKGLAVMVPI 398

Query: 289 NSIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFR 348
            ++H DP Y+ EPEKF PERF  +NK  I  + ++PFG GPR CIG RFAL  +K+ + R
Sbjct: 399 YALHHDPKYWTEPEKFCPERFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIR 458

Query: 349 LMLNFKVLKCAKTLDPIKM 367
            + NF    C +T  P+K+
Sbjct: 459 ALQNFSFKPCKETQIPLKL 477



 Score = 73.7 bits (173), Expect = 1e-12
 Identities = 41/100 (41%), Positives = 61/100 (61%), Gaps = 7/100 (7%)

Query: 23  NERYV---GFTDGVCPGIFIRDPEIIKHVTVKE-FDHFVNNKDLSPEGEESILKNSLIML 78
           NE+Y    G  +G  P + I DP++IK V VKE +  F N   L P G    LK++L   
Sbjct: 65  NEKYGEMWGLYEGQQPMLVIMDPDMIKTVLVKECYSVFTNQMPLGPMG---FLKSALSFA 121

Query: 79  KDEKWRKMRAALSPAFTASKMREMVPLITEISHNIVEYLK 118
           +DE+W+++R  LSPAFT+ K +EMVP+I++    +V  L+
Sbjct: 122 EDEEWKRIRTLLSPAFTSVKFKEMVPIISQCGDMLVRSLR 161


>AF280109-1|AAG33010.1|  504|Homo sapiens cytochrome P450 subfamily
           IIIA polypeptide 43 protein.
          Length = 504

 Score =  142 bits (343), Expect = 3e-33
 Identities = 87/260 (33%), Positives = 135/260 (51%), Gaps = 20/260 (7%)

Query: 121 FPSLS---KKLGFTIIPKSTSEFFRTLIASTVDYRIKNKVERR-DMIQLLM--QLSTEW- 173
           FP L+   + L   + PK  + F +  I    + R+K+K + R D  Q ++  Q S E  
Sbjct: 226 FPFLTPVFEALNIGLFPKDVTHFLKNSIERMKESRLKDKQKHRVDFFQQMIDSQNSKETK 285

Query: 174 -----TETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNL 228
                ++ EL AQ  +   A ++TT  TL   ++ELA  P +Q  L EE+ A    K  +
Sbjct: 286 SHKALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAPV 345

Query: 229 VYENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTV 288
            Y+ + +++YLD V+NET+R +     V R+C K   +           +  G  +   +
Sbjct: 346 TYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEI-------NGVFIPKGLAVMVPI 398

Query: 289 NSIHMDPIYYEEPEKFIPE-RFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLF 347
            ++H DP Y+ EPEKF PE RF  +NK  I  + ++PFG GPR CIG RFAL  +K+ + 
Sbjct: 399 YALHHDPKYWTEPEKFCPESRFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVI 458

Query: 348 RLMLNFKVLKCAKTLDPIKM 367
           R + NF    C +T  P+K+
Sbjct: 459 RALQNFSFKPCKETQIPLKL 478



 Score = 73.7 bits (173), Expect = 1e-12
 Identities = 41/100 (41%), Positives = 61/100 (61%), Gaps = 7/100 (7%)

Query: 23  NERYV---GFTDGVCPGIFIRDPEIIKHVTVKE-FDHFVNNKDLSPEGEESILKNSLIML 78
           NE+Y    G  +G  P + I DP++IK V VKE +  F N   L P G    LK++L   
Sbjct: 65  NEKYGEMWGLYEGQQPMLVIMDPDMIKTVLVKECYSVFTNQMPLGPMG---FLKSALSFA 121

Query: 79  KDEKWRKMRAALSPAFTASKMREMVPLITEISHNIVEYLK 118
           +DE+W+++R  LSPAFT+ K +EMVP+I++    +V  L+
Sbjct: 122 EDEEWKRIRTLLSPAFTSVKFKEMVPIISQCGDMLVRSLR 161


>AC011904-5|AAS07394.1|  504|Homo sapiens unknown protein.
          Length = 504

 Score =  142 bits (343), Expect = 3e-33
 Identities = 87/260 (33%), Positives = 135/260 (51%), Gaps = 20/260 (7%)

Query: 121 FPSLS---KKLGFTIIPKSTSEFFRTLIASTVDYRIKNKVERR-DMIQLLM--QLSTEW- 173
           FP L+   + L   + PK  + F +  I    + R+K+K + R D  Q ++  Q S E  
Sbjct: 226 FPFLTPVFEALNIGLFPKDVTHFLKNSIERMKESRLKDKQKHRVDFFQQMIDSQNSKETK 285

Query: 174 -----TETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNL 228
                ++ EL AQ  +   A ++TT  TL   ++ELA  P +Q  L EE+ A    K  +
Sbjct: 286 SHKALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAPV 345

Query: 229 VYENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTV 288
            Y+ + +++YLD V+NET+R +     V R+C K   +           +  G  +   +
Sbjct: 346 TYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEI-------NGVFIPKGLAVMVPI 398

Query: 289 NSIHMDPIYYEEPEKFIPE-RFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLF 347
            ++H DP Y+ EPEKF PE RF  +NK  I  + ++PFG GPR CIG RFAL  +K+ + 
Sbjct: 399 YALHHDPKYWTEPEKFCPESRFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVI 458

Query: 348 RLMLNFKVLKCAKTLDPIKM 367
           R + NF    C +T  P+K+
Sbjct: 459 RALQNFSFKPCKETQIPLKL 478



 Score = 73.7 bits (173), Expect = 1e-12
 Identities = 41/100 (41%), Positives = 61/100 (61%), Gaps = 7/100 (7%)

Query: 23  NERYV---GFTDGVCPGIFIRDPEIIKHVTVKE-FDHFVNNKDLSPEGEESILKNSLIML 78
           NE+Y    G  +G  P + I DP++IK V VKE +  F N   L P G    LK++L   
Sbjct: 65  NEKYGEMWGLYEGQQPMLVIMDPDMIKTVLVKECYSVFTNQMPLGPMG---FLKSALSFA 121

Query: 79  KDEKWRKMRAALSPAFTASKMREMVPLITEISHNIVEYLK 118
           +DE+W+++R  LSPAFT+ K +EMVP+I++    +V  L+
Sbjct: 122 EDEEWKRIRTLLSPAFTSVKFKEMVPIISQCGDMLVRSLR 161


>AF233624-1|AAF99278.1|  534|Homo sapiens thromboxane synthase
           protein.
          Length = 534

 Score =  119 bits (287), Expect = 2e-26
 Identities = 66/195 (33%), Positives = 104/195 (53%), Gaps = 8/195 (4%)

Query: 174 TETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYENI 233
           T  E+  Q F+F +AG+E   NTL    + LA +P  Q+ L  E+  FKE      + ++
Sbjct: 328 TVDEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSL 387

Query: 234 GE-LKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIH 292
            E L YLD V+ ET+R +  A    R   +   +   R       +  G V+   V ++H
Sbjct: 388 EEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQR-------IPAGAVLEMAVGALH 440

Query: 293 MDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLN 352
            DP ++  PE F PERF  E + + +PFT++PFG GPR C+G R  L+E+K+ L  ++  
Sbjct: 441 HDPEHWPSPENFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHK 500

Query: 353 FKVLKCAKTLDPIKM 367
           F+   C +T  P+++
Sbjct: 501 FRFQACPETQVPLQL 515



 Score = 60.9 bits (141), Expect = 8e-09
 Identities = 30/87 (34%), Positives = 54/87 (62%), Gaps = 2/87 (2%)

Query: 37  IFIRDPEIIKHVTVKEFDHFVNNKDLSPEGEESILKNSLIMLKDEKWRKMRAALSPAFTA 96
           I I +P++IK V V+ F +F N   ++   E   + +S++ L+D++W ++R AL  AF+ 
Sbjct: 89  IVISEPDMIKQVLVENFSNFTNR--MASGLEFKSVADSVLFLRDKRWEEVRGALMSAFSP 146

Query: 97  SKMREMVPLITEISHNIVEYLKDHFPS 123
            K+ EMVPLI++    ++ +LK +  S
Sbjct: 147 EKLNEMVPLISQACDLLLAHLKRYAES 173


>AF233621-1|AAF99275.1|  534|Homo sapiens thromboxane synthase
           protein.
          Length = 534

 Score =  119 bits (287), Expect = 2e-26
 Identities = 66/195 (33%), Positives = 104/195 (53%), Gaps = 8/195 (4%)

Query: 174 TETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYENI 233
           T  E+  Q F+F +AG+E   NTL    + LA +P  Q+ L  E+  FKE      + ++
Sbjct: 328 TVDEIVGQAFIFLIAGYEIITNTLSFATYVLATNPDCQEKLLREVDVFKEKHMAPEFCSL 387

Query: 234 GE-LKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIH 292
            E L YLD V+ ET+R +  A    R   +   +   R       +  G V+   V ++H
Sbjct: 388 EEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQR-------IPAGAVLEMAVGALH 440

Query: 293 MDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLN 352
            DP ++  PE F PERF  E + + +PFT++PFG GPR C+G R  L+E+K+ L  ++  
Sbjct: 441 HDPEHWPSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHK 500

Query: 353 FKVLKCAKTLDPIKM 367
           F+   C +T  P+++
Sbjct: 501 FRFQACPETQVPLQL 515



 Score = 60.9 bits (141), Expect = 8e-09
 Identities = 30/87 (34%), Positives = 54/87 (62%), Gaps = 2/87 (2%)

Query: 37  IFIRDPEIIKHVTVKEFDHFVNNKDLSPEGEESILKNSLIMLKDEKWRKMRAALSPAFTA 96
           I I +P++IK V V+ F +F N   ++   E   + +S++ L+D++W ++R AL  AF+ 
Sbjct: 89  IVISEPDMIKQVLVENFSNFTNR--MASGLEFKSVADSVLFLRDKRWEEVRGALMSAFSP 146

Query: 97  SKMREMVPLITEISHNIVEYLKDHFPS 123
            K+ EMVPLI++    ++ +LK +  S
Sbjct: 147 EKLNEMVPLISQACDLLLAHLKRYAES 173


>M80647-1|AAA60618.1|  534|Homo sapiens thromboxane synthase
           protein.
          Length = 534

 Score =  119 bits (286), Expect = 2e-26
 Identities = 66/195 (33%), Positives = 104/195 (53%), Gaps = 8/195 (4%)

Query: 174 TETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYENI 233
           T  E+  Q F+F +AG+E   NTL    + LA +P  Q+ L  E+  FKE      + ++
Sbjct: 328 TVDEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSL 387

Query: 234 GE-LKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIH 292
            E L YLD V+ ET+R +  A    R   +   +   R       +  G V+   V ++H
Sbjct: 388 EEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQR-------IPAGAVLEMAVGALH 440

Query: 293 MDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLN 352
            DP ++  PE F PERF  E + + +PFT++PFG GPR C+G R  L+E+K+ L  ++  
Sbjct: 441 HDPEHWPSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHK 500

Query: 353 FKVLKCAKTLDPIKM 367
           F+   C +T  P+++
Sbjct: 501 FRFQACPETQVPLQL 515



 Score = 60.9 bits (141), Expect = 8e-09
 Identities = 30/87 (34%), Positives = 54/87 (62%), Gaps = 2/87 (2%)

Query: 37  IFIRDPEIIKHVTVKEFDHFVNNKDLSPEGEESILKNSLIMLKDEKWRKMRAALSPAFTA 96
           I I +P++IK V V+ F +F N   ++   E   + +S++ L+D++W ++R AL  AF+ 
Sbjct: 89  IVISEPDMIKQVLVENFSNFTNR--MASGLEFKSVADSVLFLRDKRWEEVRGALMSAFSP 146

Query: 97  SKMREMVPLITEISHNIVEYLKDHFPS 123
            K+ EMVPLI++    ++ +LK +  S
Sbjct: 147 EKLNEMVPLISQACDLLLAHLKRYAES 173


>BC041157-1|AAH41157.1|  534|Homo sapiens thromboxane A synthase 1
           (platelet, cytochrome P450, family 5, subfamily A)
           protein.
          Length = 534

 Score =  119 bits (286), Expect = 2e-26
 Identities = 66/195 (33%), Positives = 104/195 (53%), Gaps = 8/195 (4%)

Query: 174 TETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYENI 233
           T  E+  Q F+F +AG+E   NTL    + LA +P  Q+ L  E+  FKE      + ++
Sbjct: 328 TVDEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSL 387

Query: 234 GE-LKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIH 292
            E L YLD V+ ET+R +  A    R   +   +   R       +  G V+   V ++H
Sbjct: 388 EEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQR-------IPAGAVLEMAVGALH 440

Query: 293 MDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLN 352
            DP ++  PE F PERF  E + + +PFT++PFG GPR C+G R  L+E+K+ L  ++  
Sbjct: 441 HDPEHWPSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHK 500

Query: 353 FKVLKCAKTLDPIKM 367
           F+   C +T  P+++
Sbjct: 501 FRFQACPETQVPLQL 515



 Score = 60.9 bits (141), Expect = 8e-09
 Identities = 30/87 (34%), Positives = 54/87 (62%), Gaps = 2/87 (2%)

Query: 37  IFIRDPEIIKHVTVKEFDHFVNNKDLSPEGEESILKNSLIMLKDEKWRKMRAALSPAFTA 96
           I I +P++IK V V+ F +F N   ++   E   + +S++ L+D++W ++R AL  AF+ 
Sbjct: 89  IVISEPDMIKQVLVENFSNFTNR--MASGLEFKSVADSVLFLRDKRWEEVRGALMSAFSP 146

Query: 97  SKMREMVPLITEISHNIVEYLKDHFPS 123
            K+ EMVPLI++    ++ +LK +  S
Sbjct: 147 EKLNEMVPLISQACDLLLAHLKRYAES 173


>BC014117-1|AAH14117.1|  466|Homo sapiens TBXAS1 protein protein.
          Length = 466

 Score =  119 bits (286), Expect = 2e-26
 Identities = 66/195 (33%), Positives = 104/195 (53%), Gaps = 8/195 (4%)

Query: 174 TETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYENI 233
           T  E+  Q F+F +AG+E   NTL    + LA +P  Q+ L  E+  FKE      + ++
Sbjct: 260 TVDEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSL 319

Query: 234 GE-LKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIH 292
            E L YLD V+ ET+R +  A    R   +   +   R       +  G V+   V ++H
Sbjct: 320 EEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQR-------IPAGAVLEMAVGALH 372

Query: 293 MDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLN 352
            DP ++  PE F PERF  E + + +PFT++PFG GPR C+G R  L+E+K+ L  ++  
Sbjct: 373 HDPEHWPSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHK 432

Query: 353 FKVLKCAKTLDPIKM 367
           F+   C +T  P+++
Sbjct: 433 FRFQACPETQVPLQL 447



 Score = 60.9 bits (141), Expect = 8e-09
 Identities = 30/87 (34%), Positives = 54/87 (62%), Gaps = 2/87 (2%)

Query: 37  IFIRDPEIIKHVTVKEFDHFVNNKDLSPEGEESILKNSLIMLKDEKWRKMRAALSPAFTA 96
           I I +P++IK V V+ F +F N   ++   E   + +S++ L+D++W ++R AL  AF+ 
Sbjct: 21  IVISEPDMIKQVLVENFSNFTNR--MASGLEFKSVADSVLFLRDKRWEEVRGALMSAFSP 78

Query: 97  SKMREMVPLITEISHNIVEYLKDHFPS 123
            K+ EMVPLI++    ++ +LK +  S
Sbjct: 79  EKLNEMVPLISQACDLLLAHLKRYAES 105


>AK223466-1|BAD97186.1|  534|Homo sapiens thromboxane A synthase 1
           (platelet, cytochrome P450, family 5, subfamily A) iso
           protein.
          Length = 534

 Score =  119 bits (286), Expect = 2e-26
 Identities = 66/195 (33%), Positives = 104/195 (53%), Gaps = 8/195 (4%)

Query: 174 TETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYENI 233
           T  E+  Q F+F +AG+E   NTL    + LA +P  Q+ L  E+  FKE      + ++
Sbjct: 328 TVDEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSL 387

Query: 234 GE-LKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIH 292
            E L YLD V+ ET+R +  A    R   +   +   R       +  G V+   V ++H
Sbjct: 388 EEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQR-------IPAGAVLEMAVGALH 440

Query: 293 MDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLN 352
            DP ++  PE F PERF  E + + +PFT++PFG GPR C+G R  L+E+K+ L  ++  
Sbjct: 441 HDPEHWPSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHK 500

Query: 353 FKVLKCAKTLDPIKM 367
           F+   C +T  P+++
Sbjct: 501 FRFQACPETQVPLQL 515



 Score = 60.9 bits (141), Expect = 8e-09
 Identities = 30/87 (34%), Positives = 54/87 (62%), Gaps = 2/87 (2%)

Query: 37  IFIRDPEIIKHVTVKEFDHFVNNKDLSPEGEESILKNSLIMLKDEKWRKMRAALSPAFTA 96
           I I +P++IK V V+ F +F N   ++   E   + +S++ L+D++W ++R AL  AF+ 
Sbjct: 89  IVISEPDMIKQVLVENFSNFTNR--MASGLEFKSVADSVLFLRDKRWEEVRGALMSAFSP 146

Query: 97  SKMREMVPLITEISHNIVEYLKDHFPS 123
            K+ EMVPLI++    ++ +LK +  S
Sbjct: 147 EKLNEMVPLISQACDLLLAHLKRYAES 173


>AF233622-1|AAF99276.1|  534|Homo sapiens thromboxane synthase
           protein.
          Length = 534

 Score =  119 bits (286), Expect = 2e-26
 Identities = 66/195 (33%), Positives = 104/195 (53%), Gaps = 8/195 (4%)

Query: 174 TETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYENI 233
           T  E+  Q F+F +AG+E   NTL    + LA +P  Q+ L  E+  FKE      + ++
Sbjct: 328 TVDEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSL 387

Query: 234 GE-LKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIH 292
            E L YLD V+ ET+R +  A    R   +   +   R       +  G V+   V ++H
Sbjct: 388 EEGLPYLDMVIAETLRMYPPAFRFTREAAEDCEVLGQR-------IPAGAVLEMAVGALH 440

Query: 293 MDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLN 352
            DP ++  PE F PERF  E + + +PFT++PFG GPR C+G R  L+E+K+ L  ++  
Sbjct: 441 HDPEHWPSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHK 500

Query: 353 FKVLKCAKTLDPIKM 367
           F+   C +T  P+++
Sbjct: 501 FRFQACPETQVPLQL 515



 Score = 60.9 bits (141), Expect = 8e-09
 Identities = 30/87 (34%), Positives = 54/87 (62%), Gaps = 2/87 (2%)

Query: 37  IFIRDPEIIKHVTVKEFDHFVNNKDLSPEGEESILKNSLIMLKDEKWRKMRAALSPAFTA 96
           I I +P++IK V V+ F +F N   ++   E   + +S++ L+D++W ++R AL  AF+ 
Sbjct: 89  IVISEPDMIKQVLVENFSNFTNR--MASGLEFKSVADSVLFLRDKRWEEVRGALMSAFSP 146

Query: 97  SKMREMVPLITEISHNIVEYLKDHFPS 123
            K+ EMVPLI++    ++ +LK +  S
Sbjct: 147 EKLNEMVPLISQACDLLLAHLKRYAES 173


>AF233620-1|AAF99274.1|  534|Homo sapiens thromboxane synthase
           protein.
          Length = 534

 Score =  119 bits (286), Expect = 2e-26
 Identities = 66/195 (33%), Positives = 104/195 (53%), Gaps = 8/195 (4%)

Query: 174 TETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYENI 233
           T  E+  Q F+F +AG+E   NTL    + LA +P  Q+ L  E+  FKE      + ++
Sbjct: 328 TVDEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSL 387

Query: 234 GE-LKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIH 292
            E L YLD V+ ET+R +  A    R   +   +   R       +  G V+   V ++H
Sbjct: 388 EEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQR-------IPAGAVLEMAVGALH 440

Query: 293 MDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLN 352
            DP ++  PE F PERF  E + + +PFT++PFG GPR C+G R  L+E+K+ L  ++  
Sbjct: 441 HDPEHWPSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHK 500

Query: 353 FKVLKCAKTLDPIKM 367
           F+   C +T  P+++
Sbjct: 501 FRFQACPETQVPLQL 515



 Score = 60.9 bits (141), Expect = 8e-09
 Identities = 30/87 (34%), Positives = 54/87 (62%), Gaps = 2/87 (2%)

Query: 37  IFIRDPEIIKHVTVKEFDHFVNNKDLSPEGEESILKNSLIMLKDEKWRKMRAALSPAFTA 96
           I I +P++IK V V+ F +F N   ++   E   + +S++ L+D++W ++R AL  AF+ 
Sbjct: 89  IVISEPDMIKQVLVENFSNFTNR--MASGLEFKSVADSVLFLRDKRWEEVRGALMSAFSP 146

Query: 97  SKMREMVPLITEISHNIVEYLKDHFPS 123
            K+ EMVPLI++    ++ +LK +  S
Sbjct: 147 EKLNEMVPLISQACDLLLAHLKRYAES 173


>AF233619-1|AAF99273.1|  534|Homo sapiens thromboxane synthase
           protein.
          Length = 534

 Score =  119 bits (286), Expect = 2e-26
 Identities = 66/195 (33%), Positives = 104/195 (53%), Gaps = 8/195 (4%)

Query: 174 TETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYENI 233
           T  E+  Q F+F +AG+E   NTL    + LA +P  Q+ L  E+  FKE      + ++
Sbjct: 328 TVDEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSL 387

Query: 234 GE-LKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIH 292
            E L YLD V+ ET+R +  A    R   +   +   R       +  G V+   V ++H
Sbjct: 388 EEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQR-------IPAGAVLEMAVGALH 440

Query: 293 MDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLN 352
            DP ++  PE F PERF  E + + +PFT++PFG GPR C+G R  L+E+K+ L  ++  
Sbjct: 441 HDPEHWPSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHK 500

Query: 353 FKVLKCAKTLDPIKM 367
           F+   C +T  P+++
Sbjct: 501 FRFQACPETQVPLQL 515



 Score = 61.3 bits (142), Expect = 6e-09
 Identities = 30/87 (34%), Positives = 54/87 (62%), Gaps = 2/87 (2%)

Query: 37  IFIRDPEIIKHVTVKEFDHFVNNKDLSPEGEESILKNSLIMLKDEKWRKMRAALSPAFTA 96
           I I +P++IK V V+ F +F N   ++   E   + +S++ L+D++W ++R AL  AF+ 
Sbjct: 89  IVISEPDMIKQVLVENFSNFTNR--MASGLEFKSVADSVLFLRDKRWEEVRGALMSAFSP 146

Query: 97  SKMREMVPLITEISHNIVEYLKDHFPS 123
            K+ EMVPLI++    ++ +LK +  S
Sbjct: 147 EKLNEMVPLISQACELLLAHLKRYAES 173


>AF233618-1|AAF99272.1|  534|Homo sapiens thromboxane synthase
           protein.
          Length = 534

 Score =  119 bits (286), Expect = 2e-26
 Identities = 66/195 (33%), Positives = 104/195 (53%), Gaps = 8/195 (4%)

Query: 174 TETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYENI 233
           T  E+  Q F+F +AG+E   NTL    + LA +P  Q+ L  E+  FKE      + ++
Sbjct: 328 TVDEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSL 387

Query: 234 GE-LKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIH 292
            E L YLD V+ ET+R +  A    R   +   +   R       +  G V+   V ++H
Sbjct: 388 EEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQR-------IPAGAVLEMAVGALH 440

Query: 293 MDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLN 352
            DP ++  PE F PERF  E + + +PFT++PFG GPR C+G R  L+E+K+ L  ++  
Sbjct: 441 HDPEHWPSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHK 500

Query: 353 FKVLKCAKTLDPIKM 367
           F+   C +T  P+++
Sbjct: 501 FRFQACPETQVPLQL 515



 Score = 60.9 bits (141), Expect = 8e-09
 Identities = 30/87 (34%), Positives = 54/87 (62%), Gaps = 2/87 (2%)

Query: 37  IFIRDPEIIKHVTVKEFDHFVNNKDLSPEGEESILKNSLIMLKDEKWRKMRAALSPAFTA 96
           I I +P++IK V V+ F +F N   ++   E   + +S++ L+D++W ++R AL  AF+ 
Sbjct: 89  IVISEPDMIKQVLVENFSNFTNR--MASGLEFKSVADSVLFLRDKRWEEVRGALMSAFSP 146

Query: 97  SKMREMVPLITEISHNIVEYLKDHFPS 123
            K+ EMVPLI++    ++ +LK +  S
Sbjct: 147 EKLNEMVPLISQACDLLLAHLKRYAES 173


>AF233617-1|AAF99271.1|  534|Homo sapiens thromboxane synthase
           protein.
          Length = 534

 Score =  119 bits (286), Expect = 2e-26
 Identities = 66/195 (33%), Positives = 104/195 (53%), Gaps = 8/195 (4%)

Query: 174 TETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYENI 233
           T  E+  Q F+F +AG+E   NTL    + LA +P  Q+ L  E+  FKE      + ++
Sbjct: 328 TVDEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSL 387

Query: 234 GE-LKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIH 292
            E L YLD V+ ET+R +  A    R   +   +   R       +  G V+   V ++H
Sbjct: 388 EEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQR-------IPAGAVLEMAVGALH 440

Query: 293 MDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLN 352
            DP ++  PE F PERF  E + + +PFT++PFG GPR C+G R  L+E+K+ L  ++  
Sbjct: 441 HDPEHWPSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHK 500

Query: 353 FKVLKCAKTLDPIKM 367
           F+   C +T  P+++
Sbjct: 501 FRFQACPETQVPLQL 515



 Score = 60.9 bits (141), Expect = 8e-09
 Identities = 30/87 (34%), Positives = 54/87 (62%), Gaps = 2/87 (2%)

Query: 37  IFIRDPEIIKHVTVKEFDHFVNNKDLSPEGEESILKNSLIMLKDEKWRKMRAALSPAFTA 96
           I I +P++IK V V+ F +F N   ++   E   + +S++ L+D++W ++R AL  AF+ 
Sbjct: 89  IVISEPDMIKQVLVENFSNFTNR--MASGLEFKSVADSVLFLRDKRWEEVRGALMSAFSP 146

Query: 97  SKMREMVPLITEISHNIVEYLKDHFPS 123
            K+ EMVPLI++    ++ +LK +  S
Sbjct: 147 EKLNEMVPLISQACDLLLAHLKRYAES 173


>AF233616-1|AAF99270.1|  534|Homo sapiens thromboxane synthase
           protein.
          Length = 534

 Score =  119 bits (286), Expect = 2e-26
 Identities = 66/195 (33%), Positives = 104/195 (53%), Gaps = 8/195 (4%)

Query: 174 TETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYENI 233
           T  E+  Q F+F +AG+E   NTL    + LA +P  Q+ L  E+  FKE      + ++
Sbjct: 328 TVDEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSL 387

Query: 234 GE-LKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIH 292
            E L YLD V+ ET+R +  A    R   +   +   R       +  G V+   V ++H
Sbjct: 388 EEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQR-------IPAGAVLEMAVGALH 440

Query: 293 MDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLN 352
            DP ++  PE F PERF  E + + +PFT++PFG GPR C+G R  L+E+K+ L  ++  
Sbjct: 441 HDPEHWPSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHK 500

Query: 353 FKVLKCAKTLDPIKM 367
           F+   C +T  P+++
Sbjct: 501 FRFQACPETQVPLQL 515



 Score = 60.9 bits (141), Expect = 8e-09
 Identities = 30/87 (34%), Positives = 54/87 (62%), Gaps = 2/87 (2%)

Query: 37  IFIRDPEIIKHVTVKEFDHFVNNKDLSPEGEESILKNSLIMLKDEKWRKMRAALSPAFTA 96
           I I +P++IK V V+ F +F N   ++   E   + +S++ L+D++W ++R AL  AF+ 
Sbjct: 89  IVISEPDMIKQVLVENFSNFTNR--MASGLEFKSVADSVLFLRDKRWEEVRGALMSAFSP 146

Query: 97  SKMREMVPLITEISHNIVEYLKDHFPS 123
            K+ EMVPLI++    ++ +LK +  S
Sbjct: 147 EKLNEMVPLISQACDLLLAHLKRYAES 173


>AF233615-1|AAF99269.1|  534|Homo sapiens thromboxane synthase
           protein.
          Length = 534

 Score =  119 bits (286), Expect = 2e-26
 Identities = 66/195 (33%), Positives = 104/195 (53%), Gaps = 8/195 (4%)

Query: 174 TETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYENI 233
           T  E+  Q F+F +AG+E   NTL    + LA +P  Q+ L  E+  FKE      + ++
Sbjct: 328 TVDEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSL 387

Query: 234 GE-LKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIH 292
            E L YLD V+ ET+R +  A    R   +   +   R       +  G V+   V ++H
Sbjct: 388 EEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQR-------IPAGAVLEMAVGALH 440

Query: 293 MDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLN 352
            DP ++  PE F PERF  E + + +PFT++PFG GPR C+G R  L+E+K+ L  ++  
Sbjct: 441 HDPEHWPSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHK 500

Query: 353 FKVLKCAKTLDPIKM 367
           F+   C +T  P+++
Sbjct: 501 FRFQACPETQVPLQL 515



 Score = 60.9 bits (141), Expect = 8e-09
 Identities = 30/87 (34%), Positives = 54/87 (62%), Gaps = 2/87 (2%)

Query: 37  IFIRDPEIIKHVTVKEFDHFVNNKDLSPEGEESILKNSLIMLKDEKWRKMRAALSPAFTA 96
           I I +P++IK V V+ F +F N   ++   E   + +S++ L+D++W ++R AL  AF+ 
Sbjct: 89  IVISEPDMIKQVLVENFSNFTNR--MASGLEFKSVADSVLFLRDKRWEEVRGALMSAFSP 146

Query: 97  SKMREMVPLITEISHNIVEYLKDHFPS 123
            K+ EMVPLI++    ++ +LK +  S
Sbjct: 147 EKLNEMVPLISQACDLLLAHLKRYAES 173


>AF233625-1|AAF99279.1|  534|Homo sapiens thromboxane synthase
           protein.
          Length = 534

 Score =  118 bits (285), Expect = 3e-26
 Identities = 66/195 (33%), Positives = 104/195 (53%), Gaps = 8/195 (4%)

Query: 174 TETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYENI 233
           T  E+  Q F+F +AG+E   NTL    + LA +P  Q+ L  E+  FKE      + ++
Sbjct: 328 TVDEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSL 387

Query: 234 GE-LKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIH 292
            E L YLD V+ ET+R +  A    R   +   +   R       +  G V+   V ++H
Sbjct: 388 EEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQR-------IPAGAVLEMAVGALH 440

Query: 293 MDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLN 352
            DP ++  PE F PERF  E + + +PFT++PFG GPR C+G R  L+E+K+ L  ++  
Sbjct: 441 HDPEHWPSPETFNPERFTAEARQQHQPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHK 500

Query: 353 FKVLKCAKTLDPIKM 367
           F+   C +T  P+++
Sbjct: 501 FRFQACPETQVPLQL 515



 Score = 60.9 bits (141), Expect = 8e-09
 Identities = 30/87 (34%), Positives = 54/87 (62%), Gaps = 2/87 (2%)

Query: 37  IFIRDPEIIKHVTVKEFDHFVNNKDLSPEGEESILKNSLIMLKDEKWRKMRAALSPAFTA 96
           I I +P++IK V V+ F +F N   ++   E   + +S++ L+D++W ++R AL  AF+ 
Sbjct: 89  IVISEPDMIKQVLVENFSNFTNR--MASGLEFKSVADSVLFLRDKRWEEVRGALMSAFSP 146

Query: 97  SKMREMVPLITEISHNIVEYLKDHFPS 123
            K+ EMVPLI++    ++ +LK +  S
Sbjct: 147 EKLNEMVPLISQACDLLLAHLKRYAES 173


>AF233623-1|AAF99277.1|  534|Homo sapiens thromboxane synthase
           protein.
          Length = 534

 Score =  117 bits (282), Expect = 6e-26
 Identities = 65/195 (33%), Positives = 104/195 (53%), Gaps = 8/195 (4%)

Query: 174 TETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYENI 233
           T  E+  Q F+F +AG+E   NTL    + LA +P  Q+ L  E+  FKE      + ++
Sbjct: 328 TVDEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSL 387

Query: 234 GE-LKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIH 292
            E L YLD V+ ET+R +  A    R   +   +   R       +  G V+   V ++H
Sbjct: 388 EEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQR-------IPAGAVLEMAVGALH 440

Query: 293 MDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLN 352
            DP ++  P+ F PERF  E + + +PFT++PFG GPR C+G R  L+E+K+ L  ++  
Sbjct: 441 HDPEHWPSPKTFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHK 500

Query: 353 FKVLKCAKTLDPIKM 367
           F+   C +T  P+++
Sbjct: 501 FRFQACPETQVPLQL 515



 Score = 60.9 bits (141), Expect = 8e-09
 Identities = 30/87 (34%), Positives = 54/87 (62%), Gaps = 2/87 (2%)

Query: 37  IFIRDPEIIKHVTVKEFDHFVNNKDLSPEGEESILKNSLIMLKDEKWRKMRAALSPAFTA 96
           I I +P++IK V V+ F +F N   ++   E   + +S++ L+D++W ++R AL  AF+ 
Sbjct: 89  IVISEPDMIKQVLVENFSNFTNR--MASGLEFKSVADSVLFLRDKRWEEVRGALMSAFSP 146

Query: 97  SKMREMVPLITEISHNIVEYLKDHFPS 123
            K+ EMVPLI++    ++ +LK +  S
Sbjct: 147 EKLNEMVPLISQACDLLLAHLKRYAES 173


>D34625-1|BAA07011.1|  533|Homo sapiens thromboxane synthase
           protein.
          Length = 533

 Score =  117 bits (281), Expect = 8e-26
 Identities = 65/195 (33%), Positives = 103/195 (52%), Gaps = 8/195 (4%)

Query: 174 TETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYENI 233
           T  E+  Q F+F +AG+E   NTL    + LA +P  Q+ L  E+  FKE      + ++
Sbjct: 327 TVDEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSL 386

Query: 234 GE-LKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIH 292
            E L YLD V+ ET+R +  A    R   +   +   R       +  G V+   V ++H
Sbjct: 387 EEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQR-------IPAGAVLEMAVGALH 439

Query: 293 MDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLN 352
            DP ++  PE F PERF  E + + +PFT++PFG GPR C+G    L+E+K+ L  ++  
Sbjct: 440 HDPEHWPSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVHLGLLEVKLTLLHVLHK 499

Query: 353 FKVLKCAKTLDPIKM 367
           F+   C +T  P+++
Sbjct: 500 FRFQACPETQVPLQL 514



 Score = 60.9 bits (141), Expect = 8e-09
 Identities = 30/87 (34%), Positives = 54/87 (62%), Gaps = 2/87 (2%)

Query: 37  IFIRDPEIIKHVTVKEFDHFVNNKDLSPEGEESILKNSLIMLKDEKWRKMRAALSPAFTA 96
           I I +P++IK V V+ F +F N   ++   E   + +S++ L+D++W ++R AL  AF+ 
Sbjct: 88  IVISEPDMIKQVLVENFSNFTNR--MASGLEFKSVADSVLFLRDKRWEEVRGALMSAFSP 145

Query: 97  SKMREMVPLITEISHNIVEYLKDHFPS 123
            K+ EMVPLI++    ++ +LK +  S
Sbjct: 146 EKLNEMVPLISQACDLLLAHLKRYAES 172


>AJ563378-3|CAD91347.1|  173|Homo sapiens hypothetical protein
           protein.
          Length = 173

 Score =  110 bits (264), Expect = 9e-24
 Identities = 55/142 (38%), Positives = 82/142 (57%), Gaps = 8/142 (5%)

Query: 230 YENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVN 289
           Y+ + +++YLD V+NET+R +  AI ++R C K   +           +  G ++     
Sbjct: 18  YDAVVQMEYLDMVVNETLRLFPVAIRLERTCKKDVEI-------NGVFIPKGSMVVIPTY 70

Query: 290 SIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRL 349
           ++H DP Y+ EPE+F PERF  + K  I P+ + PFG GPR CIG RFALM MK+ L R+
Sbjct: 71  ALHHDPKYWTEPEEFRPERF-SKKKDSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRV 129

Query: 350 MLNFKVLKCAKTLDPIKMSPVG 371
           + NF    C +T  P+K+   G
Sbjct: 130 LQNFSFKPCKETQIPLKLDTQG 151


>AJ563378-2|CAD91647.1|  160|Homo sapiens cytochrome P450 protein.
          Length = 160

 Score =  110 bits (264), Expect = 9e-24
 Identities = 55/142 (38%), Positives = 82/142 (57%), Gaps = 8/142 (5%)

Query: 230 YENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVN 289
           Y+ + +++YLD V+NET+R +  AI ++R C K   +           +  G ++     
Sbjct: 5   YDAVVQMEYLDMVVNETLRLFPVAIRLERTCKKDVEI-------NGVFIPKGSMVVIPTY 57

Query: 290 SIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRL 349
           ++H DP Y+ EPE+F PERF  + K  I P+ + PFG GPR CIG RFALM MK+ L R+
Sbjct: 58  ALHHDPKYWTEPEEFRPERF-SKKKDSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRV 116

Query: 350 MLNFKVLKCAKTLDPIKMSPVG 371
           + NF    C +T  P+K+   G
Sbjct: 117 LQNFSFKPCKETQIPLKLDTQG 138


>AY358631-1|AAQ88994.1|  505|Homo sapiens EPSW3060 protein.
          Length = 505

 Score =  109 bits (261), Expect = 2e-23
 Identities = 56/201 (27%), Positives = 105/201 (52%), Gaps = 10/201 (4%)

Query: 159 RRDMIQLLMQLSTE----WTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDIL 214
           R D + +L+   +E    ++E +L A++  F  AG +TT + +   ++ LA  P  Q   
Sbjct: 281 RWDFLDILLSAKSENTKDFSEADLQAEVKTFMFAGHDTTSSAISWILYCLAKYPEHQQRC 340

Query: 215 YEELKAFKETKGNLVYENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGK 274
            +E++       ++ +E++ ++ Y    + E +R ++  + + R+  KP   P  R    
Sbjct: 341 RDEIRELLGDGSSITWEHLSQMPYTTMCIKECLRLYAPVVNISRLLDKPITFPDGRS--- 397

Query: 275 PCQLKPGEVIYNTVNSIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIG 334
              L  G  ++  + ++H +P ++E+P+ F P RF  EN  KI P+ F+PF  G R CIG
Sbjct: 398 ---LPAGITVFINIWALHHNPYFWEDPQVFNPLRFSRENSEKIHPYAFIPFSAGLRNCIG 454

Query: 335 SRFALMEMKILLFRLMLNFKV 355
             FA++E K+ +   +L FK+
Sbjct: 455 QHFAIIECKVAVALTLLRFKL 475



 Score = 31.5 bits (68), Expect = 5.3
 Identities = 14/59 (23%), Positives = 29/59 (49%)

Query: 68  ESILKNSLIMLKDEKWRKMRAALSPAFTASKMREMVPLITEISHNIVEYLKDHFPSLSK 126
           ES +   L+ L   KW+K R  + P F  S ++  + +++E    ++   ++H    S+
Sbjct: 118 ESWVGRGLVTLDGSKWKKHRQIVKPGFNISILKIFITMMSESVRMMLNKWEEHIAQNSR 176


>AY262056-1|AAO89257.1|  505|Homo sapiens cytochrome P450 protein.
          Length = 505

 Score =  109 bits (261), Expect = 2e-23
 Identities = 56/201 (27%), Positives = 105/201 (52%), Gaps = 10/201 (4%)

Query: 159 RRDMIQLLMQLSTE----WTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDIL 214
           R D + +L+   +E    ++E +L A++  F  AG +TT + +   ++ LA  P  Q   
Sbjct: 281 RWDFLDILLSAKSENTKDFSEADLQAEVKTFMFAGHDTTSSAISWILYCLAKYPEHQQRC 340

Query: 215 YEELKAFKETKGNLVYENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGK 274
            +E++       ++ +E++ ++ Y    + E +R ++  + + R+  KP   P  R    
Sbjct: 341 RDEIRELLGDGSSITWEHLSQMPYTTMCIKECLRLYAPVVNISRLLDKPITFPDGRS--- 397

Query: 275 PCQLKPGEVIYNTVNSIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIG 334
              L  G  ++  + ++H +P ++E+P+ F P RF  EN  KI P+ F+PF  G R CIG
Sbjct: 398 ---LPAGITVFINIWALHHNPYFWEDPQVFNPLRFSRENSEKIHPYAFIPFSAGLRNCIG 454

Query: 335 SRFALMEMKILLFRLMLNFKV 355
             FA++E K+ +   +L FK+
Sbjct: 455 QHFAIIECKVAVALTLLRFKL 475



 Score = 31.5 bits (68), Expect = 5.3
 Identities = 14/59 (23%), Positives = 29/59 (49%)

Query: 68  ESILKNSLIMLKDEKWRKMRAALSPAFTASKMREMVPLITEISHNIVEYLKDHFPSLSK 126
           ES +   L+ L   KW+K R  + P F  S ++  + +++E    ++   ++H    S+
Sbjct: 118 ESWVGRGLVTLDGSKWKKHRQIVKPGFNISILKIFITMMSESVRMMLNKWEEHIAQNSR 176


>AL450996-2|CAH71036.1|  505|Homo sapiens cytochrome P450, family 4,
           subfamily Z, polypeptide 1 protein.
          Length = 505

 Score =  109 bits (261), Expect = 2e-23
 Identities = 56/201 (27%), Positives = 105/201 (52%), Gaps = 10/201 (4%)

Query: 159 RRDMIQLLMQLSTE----WTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDIL 214
           R D + +L+   +E    ++E +L A++  F  AG +TT + +   ++ LA  P  Q   
Sbjct: 281 RWDFLDILLSAKSENTKDFSEADLQAEVKTFMFAGHDTTSSAISWILYCLAKYPEHQQRC 340

Query: 215 YEELKAFKETKGNLVYENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGK 274
            +E++       ++ +E++ ++ Y    + E +R ++  + + R+  KP   P  R    
Sbjct: 341 RDEIRELLGDGSSITWEHLSQMPYTTMCIKECLRLYAPVVNISRLLDKPITFPDGRS--- 397

Query: 275 PCQLKPGEVIYNTVNSIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIG 334
              L  G  ++  + ++H +P ++E+P+ F P RF  EN  KI P+ F+PF  G R CIG
Sbjct: 398 ---LPAGITVFINIWALHHNPYFWEDPQVFNPLRFSRENSEKIHPYAFIPFSAGLRNCIG 454

Query: 335 SRFALMEMKILLFRLMLNFKV 355
             FA++E K+ +   +L FK+
Sbjct: 455 QHFAIIECKVAVALTLLRFKL 475



 Score = 31.5 bits (68), Expect = 5.3
 Identities = 14/59 (23%), Positives = 29/59 (49%)

Query: 68  ESILKNSLIMLKDEKWRKMRAALSPAFTASKMREMVPLITEISHNIVEYLKDHFPSLSK 126
           ES +   L+ L   KW+K R  + P F  S ++  + +++E    ++   ++H    S+
Sbjct: 118 ESWVGRGLVTLDGSKWKKHRQIVKPGFNISILKIFITMMSESVRMMLNKWEEHIAQNSR 176


>AL135960-6|CAI19734.1|  505|Homo sapiens cytochrome P450, family 4,
           subfamily Z, polypeptide 1 protein.
          Length = 505

 Score =  109 bits (261), Expect = 2e-23
 Identities = 56/201 (27%), Positives = 105/201 (52%), Gaps = 10/201 (4%)

Query: 159 RRDMIQLLMQLSTE----WTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDIL 214
           R D + +L+   +E    ++E +L A++  F  AG +TT + +   ++ LA  P  Q   
Sbjct: 281 RWDFLDILLSAKSENTKDFSEADLQAEVKTFMFAGHDTTSSAISWILYCLAKYPEHQQRC 340

Query: 215 YEELKAFKETKGNLVYENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGK 274
            +E++       ++ +E++ ++ Y    + E +R ++  + + R+  KP   P  R    
Sbjct: 341 RDEIRELLGDGSSITWEHLSQMPYTTMCIKECLRLYAPVVNISRLLDKPITFPDGRS--- 397

Query: 275 PCQLKPGEVIYNTVNSIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIG 334
              L  G  ++  + ++H +P ++E+P+ F P RF  EN  KI P+ F+PF  G R CIG
Sbjct: 398 ---LPAGITVFINIWALHHNPYFWEDPQVFNPLRFSRENSEKIHPYAFIPFSAGLRNCIG 454

Query: 335 SRFALMEMKILLFRLMLNFKV 355
             FA++E K+ +   +L FK+
Sbjct: 455 QHFAIIECKVAVALTLLRFKL 475



 Score = 31.5 bits (68), Expect = 5.3
 Identities = 14/59 (23%), Positives = 29/59 (49%)

Query: 68  ESILKNSLIMLKDEKWRKMRAALSPAFTASKMREMVPLITEISHNIVEYLKDHFPSLSK 126
           ES +   L+ L   KW+K R  + P F  S ++  + +++E    ++   ++H    S+
Sbjct: 118 ESWVGRGLVTLDGSKWKKHRQIVKPGFNISILKIFITMMSESVRMMLNKWEEHIAQNSR 176


>BC016853-1|AAH16853.1|  524|Homo sapiens CYP4F11 protein protein.
          Length = 524

 Score =  105 bits (252), Expect = 3e-22
 Identities = 64/223 (28%), Positives = 114/223 (51%), Gaps = 14/223 (6%)

Query: 142 RTLIASTVDYRIKNKVERR--DMIQLLM----QLSTEWTETELAAQLFVFFVAGFETTGN 195
           RTL    +D  +KNK + +  D I +L+    +   E ++ ++ A+   F   G +TT +
Sbjct: 276 RTLPTQGIDDFLKNKAKSKTLDFIDVLLLSKDEDGKELSDEDIRAEADTFMFEGHDTTAS 335

Query: 196 TLINCIHELALSPHIQDILYEELKAFKETKG--NLVYENIGELKYLDCVLNETMRKWSAA 253
            L   ++ LA  P  Q+   +E++   + +    + ++++ +L +L   + E++R     
Sbjct: 336 GLSWVLYHLAKHPEYQEQCRQEVQELLKDREPIEIEWDDLAQLPFLTMCIKESLRLHPPV 395

Query: 254 IFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHMDPIYYEEPEKFIPERFLDEN 313
             + R CT+ +VLP  R       +  G V    +  IH +P  + +PE + P RF  EN
Sbjct: 396 PVISRCCTQDFVLPDGRV------IPKGIVCLINIIGIHYNPTVWPDPEVYDPFRFNQEN 449

Query: 314 KHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVL 356
             +  P  F+PF  GPR CIG  FA+ EMK++L   +L+F++L
Sbjct: 450 IKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALTLLHFRIL 492


>AF236085-1|AAG15889.1|  524|Homo sapiens CYP4F11 protein.
          Length = 524

 Score =  105 bits (252), Expect = 3e-22
 Identities = 64/223 (28%), Positives = 114/223 (51%), Gaps = 14/223 (6%)

Query: 142 RTLIASTVDYRIKNKVERR--DMIQLLM----QLSTEWTETELAAQLFVFFVAGFETTGN 195
           RTL    +D  +KNK + +  D I +L+    +   E ++ ++ A+   F   G +TT +
Sbjct: 276 RTLPTQGIDDFLKNKAKSKTLDFIDVLLLSKDEDGKELSDEDIRAEADTFMFEGHDTTAS 335

Query: 196 TLINCIHELALSPHIQDILYEELKAFKETKG--NLVYENIGELKYLDCVLNETMRKWSAA 253
            L   ++ LA  P  Q+   +E++   + +    + ++++ +L +L   + E++R     
Sbjct: 336 GLSWVLYHLAKHPEYQEQCRQEVQELLKDREPIEIEWDDLAQLPFLTMCIKESLRLHPPV 395

Query: 254 IFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHMDPIYYEEPEKFIPERFLDEN 313
             + R CT+ +VLP  R       +  G V    +  IH +P  + +PE + P RF  EN
Sbjct: 396 PVISRCCTQDFVLPDGRV------IPKGIVCLINIIGIHYNPTVWPDPEVYDPFRFNQEN 449

Query: 314 KHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVL 356
             +  P  F+PF  GPR CIG  FA+ EMK++L   +L+F++L
Sbjct: 450 IKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALTLLHFRIL 492


>AF133298-1|AAD49566.1|  520|Homo sapiens cytochrome P450 protein.
          Length = 520

 Score =  101 bits (242), Expect = 4e-21
 Identities = 66/223 (29%), Positives = 112/223 (50%), Gaps = 14/223 (6%)

Query: 142 RTLIASTVD--YRIKNKVERRDMIQLLM----QLSTEWTETELAAQLFVFFVAGFETTGN 195
           RTL +  VD   + K K +  D I +L+    +   E ++ ++ A+   F   G +TT +
Sbjct: 276 RTLTSQGVDDFLQAKAKSKTLDFIDVLLLSEDKNGKELSDEDIRAEADTFMFGGHDTTAS 335

Query: 196 TLINCIHELALSPHIQDILYEELKAFKETKG--NLVYENIGELKYLDCVLNETMRKWSAA 253
            L   ++ LA  P  Q+   +E++   + +    + ++++ +L +L   L E++R     
Sbjct: 336 GLSWVLYNLARHPEYQERCRQEVQELLKDREPKEIEWDDLAQLPFLTMCLKESLRLHPPI 395

Query: 254 IFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHMDPIYYEEPEKFIPERFLDEN 313
               R CT+  VLP  R       +  G V    + +IH +P  + +PE + P RF  EN
Sbjct: 396 PTFARGCTQDVVLPDSRV------IPKGNVCNINIFAIHHNPSVWPDPEVYDPFRFDPEN 449

Query: 314 KHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVL 356
             K  P  F+PF  GPR CIG +FA+ EMK++L   +L F++L
Sbjct: 450 AQKRSPMAFIPFSAGPRNCIGQKFAMAEMKVVLALTLLRFRIL 492


>BC035350-1|AAH35350.1|  524|Homo sapiens cytochrome P450, family 4,
           subfamily F, polypeptide 12 protein.
          Length = 524

 Score =  101 bits (241), Expect = 6e-21
 Identities = 63/223 (28%), Positives = 111/223 (49%), Gaps = 14/223 (6%)

Query: 142 RTLIASTVDYRIKNKVERR--DMIQLLMQLSTE----WTETELAAQLFVFFVAGFETTGN 195
           RTL    +D   K+K + +  D I +L+    E     ++ ++ A+   F   G +TT +
Sbjct: 276 RTLPTQGIDDFFKDKAKSKTLDFIDVLLLSKDEDGKALSDEDIRAEADTFMFGGHDTTAS 335

Query: 196 TLINCIHELALSPHIQDILYEELKAFKETKG--NLVYENIGELKYLDCVLNETMRKWSAA 253
            L   ++ LA  P  Q+   +E++   + +    + ++++ +L +L   + E++R    A
Sbjct: 336 GLSWVLYNLARHPEYQERCRQEVQELLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPA 395

Query: 254 IFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHMDPIYYEEPEKFIPERFLDEN 313
            F+ R CT+  VLP  R       +  G      +  +H +P  + +PE + P RF  EN
Sbjct: 396 PFISRCCTQDIVLPDGRV------IPKGITCLIDIIGVHHNPTVWPDPEVYDPFRFDPEN 449

Query: 314 KHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVL 356
                P  F+PF  GPR CIG  FA+ EMK++L  ++L+F+ L
Sbjct: 450 SKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFL 492


>BC028102-1|AAH28102.1|  509|Homo sapiens cytochrome P450, family 4,
           subfamily X, polypeptide 1 protein.
          Length = 509

 Score =  101 bits (241), Expect = 6e-21
 Identities = 50/185 (27%), Positives = 100/185 (54%), Gaps = 6/185 (3%)

Query: 171 TEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVY 230
           + +++ ++ +++  F +AG +T   ++   ++ LAL+P  Q+   EE++       ++ +
Sbjct: 299 SSFSDIDVHSEVSTFLLAGHDTLAASISWILYCLALNPEHQERCREEVRGILGDGSSITW 358

Query: 231 ENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNS 290
           + +GE+ Y    + ET R   A   + R  +KP   P   +G   C L  G  +  ++  
Sbjct: 359 DQLGEMSYTTMCIKETCRLIPAVPSISRDLSKPLTFP---DG---CTLPAGITVVLSIWG 412

Query: 291 IHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLM 350
           +H +P  ++ P+ F P RF  EN  +  P+ ++PF  G R CIG  FA++E+K+ +  ++
Sbjct: 413 LHHNPAVWKNPKVFDPLRFSQENSDQRHPYAYLPFSAGSRNCIGQEFAMIELKVTIALIL 472

Query: 351 LNFKV 355
           L+F+V
Sbjct: 473 LHFRV 477


>AY358977-1|AAQ89336.1|  524|Homo sapiens CYP4F12 protein.
          Length = 524

 Score =  101 bits (241), Expect = 6e-21
 Identities = 63/223 (28%), Positives = 111/223 (49%), Gaps = 14/223 (6%)

Query: 142 RTLIASTVDYRIKNKVERR--DMIQLLMQLSTE----WTETELAAQLFVFFVAGFETTGN 195
           RTL    +D   K+K + +  D I +L+    E     ++ ++ A+   F   G +TT +
Sbjct: 276 RTLPTQGIDDFFKDKAKSKTLDFIDVLLLSKDEDGKALSDEDIRAEADTFMFGGHDTTAS 335

Query: 196 TLINCIHELALSPHIQDILYEELKAFKETKG--NLVYENIGELKYLDCVLNETMRKWSAA 253
            L   ++ LA  P  Q+   +E++   + +    + ++++ +L +L   + E++R    A
Sbjct: 336 GLSWVLYNLARHPEYQERCRQEVQELLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPA 395

Query: 254 IFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHMDPIYYEEPEKFIPERFLDEN 313
            F+ R CT+  VLP  R       +  G      +  +H +P  + +PE + P RF  EN
Sbjct: 396 PFISRCCTQDIVLPDGRV------IPKGITCLIDIIGVHHNPTVWPDPEVYDPFRFDPEN 449

Query: 314 KHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVL 356
                P  F+PF  GPR CIG  FA+ EMK++L  ++L+F+ L
Sbjct: 450 SKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFL 492


>AY358537-1|AAQ88901.1|  509|Homo sapiens EFSW1929 protein.
          Length = 509

 Score =  101 bits (241), Expect = 6e-21
 Identities = 50/185 (27%), Positives = 100/185 (54%), Gaps = 6/185 (3%)

Query: 171 TEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVY 230
           + +++ ++ +++  F +AG +T   ++   ++ LAL+P  Q+   EE++       ++ +
Sbjct: 299 SSFSDIDVHSEVSTFLLAGHDTLAASISWILYCLALNPEHQERCREEVRGILGDGSSITW 358

Query: 231 ENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNS 290
           + +GE+ Y    + ET R   A   + R  +KP   P   +G   C L  G  +  ++  
Sbjct: 359 DQLGEMSYTTMCIKETCRLIPAVPSISRDLSKPLTFP---DG---CTLPAGITVVLSIWG 412

Query: 291 IHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLM 350
           +H +P  ++ P+ F P RF  EN  +  P+ ++PF  G R CIG  FA++E+K+ +  ++
Sbjct: 413 LHHNPAVWKNPKVFDPLRFSQENSDQRHPYAYLPFSAGSRNCIGQEFAMIELKVTIALIL 472

Query: 351 LNFKV 355
           L+F+V
Sbjct: 473 LHFRV 477


>AY008841-1|AAG33247.1|  524|Homo sapiens cytochrome P450 isoform
           4F12 protein.
          Length = 524

 Score =  101 bits (241), Expect = 6e-21
 Identities = 63/223 (28%), Positives = 111/223 (49%), Gaps = 14/223 (6%)

Query: 142 RTLIASTVDYRIKNKVERR--DMIQLLMQLSTE----WTETELAAQLFVFFVAGFETTGN 195
           RTL    +D   K+K + +  D I +L+    E     ++ ++ A+   F   G +TT +
Sbjct: 276 RTLPTQGIDDFFKDKAKSKTLDFIDVLLLSKDEDGKALSDEDIRAEADTFMFGGHDTTAS 335

Query: 196 TLINCIHELALSPHIQDILYEELKAFKETKG--NLVYENIGELKYLDCVLNETMRKWSAA 253
            L   ++ LA  P  Q+   +E++   + +    + ++++ +L +L   + E++R    A
Sbjct: 336 GLSWVLYNLARHPEYQERCRQEVQELLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPA 395

Query: 254 IFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHMDPIYYEEPEKFIPERFLDEN 313
            F+ R CT+  VLP  R       +  G      +  +H +P  + +PE + P RF  EN
Sbjct: 396 PFISRCCTQDIVLPDGRV------IPKGITCLIDIIGVHHNPTVWPDPEVYDPFRFDPEN 449

Query: 314 KHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVL 356
                P  F+PF  GPR CIG  FA+ EMK++L  ++L+F+ L
Sbjct: 450 SKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFL 492


>AM040940-1|CAJ13826.1|  509|Homo sapiens cytochrome P450 protein.
          Length = 509

 Score =  101 bits (241), Expect = 6e-21
 Identities = 50/185 (27%), Positives = 100/185 (54%), Gaps = 6/185 (3%)

Query: 171 TEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVY 230
           + +++ ++ +++  F +AG +T   ++   ++ LAL+P  Q+   EE++       ++ +
Sbjct: 299 SSFSDIDVHSEVSTFLLAGHDTLAASISWILYCLALNPEHQERCREEVRGILGDGSSITW 358

Query: 231 ENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNS 290
           + +GE+ Y    + ET R   A   + R  +KP   P   +G   C L  G  +  ++  
Sbjct: 359 DQLGEMSYTTMCIKETCRLIPAVPSISRDLSKPLTFP---DG---CTLPAGITVVLSIWG 412

Query: 291 IHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLM 350
           +H +P  ++ P+ F P RF  EN  +  P+ ++PF  G R CIG  FA++E+K+ +  ++
Sbjct: 413 LHHNPAVWKNPKVFDPLRFSQENSDQRHPYAYLPFSAGSRNCIGQEFAMIELKVTIALIL 472

Query: 351 LNFKV 355
           L+F+V
Sbjct: 473 LHFRV 477


>AL450996-1|CAH71035.1|  509|Homo sapiens cytochrome P450, family 4,
           subfamily X, polypeptide 1 protein.
          Length = 509

 Score =  101 bits (241), Expect = 6e-21
 Identities = 50/185 (27%), Positives = 100/185 (54%), Gaps = 6/185 (3%)

Query: 171 TEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVY 230
           + +++ ++ +++  F +AG +T   ++   ++ LAL+P  Q+   EE++       ++ +
Sbjct: 299 SSFSDIDVHSEVSTFLLAGHDTLAASISWILYCLALNPEHQERCREEVRGILGDGSSITW 358

Query: 231 ENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNS 290
           + +GE+ Y    + ET R   A   + R  +KP   P   +G   C L  G  +  ++  
Sbjct: 359 DQLGEMSYTTMCIKETCRLIPAVPSISRDLSKPLTFP---DG---CTLPAGITVVLSIWG 412

Query: 291 IHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLM 350
           +H +P  ++ P+ F P RF  EN  +  P+ ++PF  G R CIG  FA++E+K+ +  ++
Sbjct: 413 LHHNPAVWKNPKVFDPLRFSQENSDQRHPYAYLPFSAGSRNCIGQEFAMIELKVTIALIL 472

Query: 351 LNFKV 355
           L+F+V
Sbjct: 473 LHFRV 477


>AK131355-1|BAD18508.1|  508|Homo sapiens protein ( Homo sapiens
           cDNA FLJ16384 fis, clone TLIVE2007607, weakly  similar
           to CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
          Length = 508

 Score =  101 bits (241), Expect = 6e-21
 Identities = 50/185 (27%), Positives = 100/185 (54%), Gaps = 6/185 (3%)

Query: 171 TEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVY 230
           + +++ ++ +++  F +AG +T   ++   ++ LAL+P  Q+   EE++       ++ +
Sbjct: 298 SSFSDIDVHSEVSTFLLAGHDTLAASISWILYCLALNPEHQERCREEVRGILGDGSSITW 357

Query: 231 ENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNS 290
           + +GE+ Y    + ET R   A   + R  +KP   P   +G   C L  G  +  ++  
Sbjct: 358 DQLGEMSYTTMCIKETCRLIPAVPSISRDLSKPLTFP---DG---CTLPAGITVVLSIWG 411

Query: 291 IHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLM 350
           +H +P  ++ P+ F P RF  EN  +  P+ ++PF  G R CIG  FA++E+K+ +  ++
Sbjct: 412 LHHNPAVWKNPKVFDPLRFSQENSDQRHPYAYLPFSAGSRNCIGQEFAMIELKVTIALIL 471

Query: 351 LNFKV 355
           L+F+V
Sbjct: 472 LHFRV 476


>AK098065-1|BAC05226.1|  509|Homo sapiens protein ( Homo sapiens
           cDNA FLJ40746 fis, clone TRACH2000359, weakly similar to
           CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
          Length = 509

 Score =  101 bits (241), Expect = 6e-21
 Identities = 50/185 (27%), Positives = 100/185 (54%), Gaps = 6/185 (3%)

Query: 171 TEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVY 230
           + +++ ++ +++  F +AG +T   ++   ++ LAL+P  Q+   EE++       ++ +
Sbjct: 299 SSFSDIDVHSEVSTFLLAGHDTLAASISWILYCLALNPEHQERCREEVRGILGDGSSITW 358

Query: 231 ENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNS 290
           + +GE+ Y    + ET R   A   + R  +KP   P   +G   C L  G  +  ++  
Sbjct: 359 DQLGEMSYTTMCIKETCRLIPAVPSISRDLSKPLTFP---DG---CTLPAGITVVLSIWG 412

Query: 291 IHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLM 350
           +H +P  ++ P+ F P RF  EN  +  P+ ++PF  G R CIG  FA++E+K+ +  ++
Sbjct: 413 LHHNPAVWKNPKVFDPLRFSQENSDQRHPYAYLPFSAGSRNCIGQEFAMIELKVTIALIL 472

Query: 351 LNFKV 355
           L+F+V
Sbjct: 473 LHFRV 477


>AK091806-1|BAC03751.1|  444|Homo sapiens protein ( Homo sapiens
           cDNA FLJ34487 fis, clone HLUNG2004273, weakly similar to
           CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
          Length = 444

 Score =  101 bits (241), Expect = 6e-21
 Identities = 50/185 (27%), Positives = 100/185 (54%), Gaps = 6/185 (3%)

Query: 171 TEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVY 230
           + +++ ++ +++  F +AG +T   ++   ++ LAL+P  Q+   EE++       ++ +
Sbjct: 234 SSFSDIDVHSEVSTFLLAGHDTLAASISWILYCLALNPEHQERCREEVRGILGDGSSITW 293

Query: 231 ENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNS 290
           + +GE+ Y    + ET R   A   + R  +KP   P   +G   C L  G  +  ++  
Sbjct: 294 DQLGEMSYTTMCIKETCRLIPAVPSISRDLSKPLTFP---DG---CTLPAGITVVLSIWG 347

Query: 291 IHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLM 350
           +H +P  ++ P+ F P RF  EN  +  P+ ++PF  G R CIG  FA++E+K+ +  ++
Sbjct: 348 LHHNPAVWKNPKVFDPLRFSQENSDQRHPYAYLPFSAGSRNCIGQEFAMIELKVTIALIL 407

Query: 351 LNFKV 355
           L+F+V
Sbjct: 408 LHFRV 412


>AC004523-1|AAC11543.1|  458|Homo sapiens F22329_1 protein.
          Length = 458

 Score =  101 bits (241), Expect = 6e-21
 Identities = 63/223 (28%), Positives = 111/223 (49%), Gaps = 14/223 (6%)

Query: 142 RTLIASTVDYRIKNKVERR--DMIQLLMQLSTE----WTETELAAQLFVFFVAGFETTGN 195
           RTL    +D   K+K + +  D I +L+    E     ++ ++ A+   F   G +TT +
Sbjct: 210 RTLPTQGIDDFFKDKAKSKTLDFIDVLLLSKDEDGKALSDEDIRAEADTFMFGGHDTTAS 269

Query: 196 TLINCIHELALSPHIQDILYEELKAFKETKG--NLVYENIGELKYLDCVLNETMRKWSAA 253
            L   ++ LA  P  Q+   +E++   + +    + ++++ +L +L   + E++R    A
Sbjct: 270 GLSWVLYNLARHPEYQERCRQEVQELLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPA 329

Query: 254 IFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHMDPIYYEEPEKFIPERFLDEN 313
            F+ R CT+  VLP  R       +  G      +  +H +P  + +PE + P RF  EN
Sbjct: 330 PFISRCCTQDIVLPDGRV------IPKGITCLIDIIGVHHNPTVWPDPEVYDPFRFDPEN 383

Query: 314 KHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVL 356
                P  F+PF  GPR CIG  FA+ EMK++L  ++L+F+ L
Sbjct: 384 SKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFL 426


>AB035131-1|BAB18270.1|  524|Homo sapiens cytochrome P450 protein.
          Length = 524

 Score =  101 bits (241), Expect = 6e-21
 Identities = 63/223 (28%), Positives = 111/223 (49%), Gaps = 14/223 (6%)

Query: 142 RTLIASTVDYRIKNKVERR--DMIQLLMQLSTE----WTETELAAQLFVFFVAGFETTGN 195
           RTL    +D   K+K + +  D I +L+    E     ++ ++ A+   F   G +TT +
Sbjct: 276 RTLPTQGIDDFFKDKAKSKTLDFIDVLLLSKDEDGKALSDEDIRAEADTFMFGGHDTTAS 335

Query: 196 TLINCIHELALSPHIQDILYEELKAFKETKG--NLVYENIGELKYLDCVLNETMRKWSAA 253
            L   ++ LA  P  Q+   +E++   + +    + ++++ +L +L   + E++R    A
Sbjct: 336 GLSWVLYNLARHPEYQERCRQEVQELLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPA 395

Query: 254 IFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHMDPIYYEEPEKFIPERFLDEN 313
            F+ R CT+  VLP  R       +  G      +  +H +P  + +PE + P RF  EN
Sbjct: 396 PFISRCCTQDIVLPDGRV------IPKGITCLIDIIGVHHNPTVWPDPEVYDPFRFDPEN 449

Query: 314 KHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVL 356
                P  F+PF  GPR CIG  FA+ EMK++L  ++L+F+ L
Sbjct: 450 SKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFL 492


>AB035130-1|BAB18269.1|  524|Homo sapiens cytochrome P450 protein.
          Length = 524

 Score =  101 bits (241), Expect = 6e-21
 Identities = 63/223 (28%), Positives = 111/223 (49%), Gaps = 14/223 (6%)

Query: 142 RTLIASTVDYRIKNKVERR--DMIQLLMQLSTE----WTETELAAQLFVFFVAGFETTGN 195
           RTL    +D   K+K + +  D I +L+    E     ++ ++ A+   F   G +TT +
Sbjct: 276 RTLPTQGIDDFFKDKAKSKTLDFIDVLLLSKDEDGKALSDEDIRAEADTFMFGGHDTTAS 335

Query: 196 TLINCIHELALSPHIQDILYEELKAFKETKG--NLVYENIGELKYLDCVLNETMRKWSAA 253
            L   ++ LA  P  Q+   +E++   + +    + ++++ +L +L   + E++R    A
Sbjct: 336 GLSWVLYNLARHPEYQERCRQEVQELLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPA 395

Query: 254 IFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHMDPIYYEEPEKFIPERFLDEN 313
            F+ R CT+  VLP  R       +  G      +  +H +P  + +PE + P RF  EN
Sbjct: 396 PFISRCCTQDIVLPDGRV------IPKGITCLIDIIGVHHNPTVWPDPEVYDPFRFDPEN 449

Query: 314 KHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVL 356
                P  F+PF  GPR CIG  FA+ EMK++L  ++L+F+ L
Sbjct: 450 SKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFL 492


>X16699-1|CAA34672.1|  511|Homo sapiens protein ( Human mRNA for
           cytochrome P-450HP. ).
          Length = 511

 Score = 97.9 bits (233), Expect = 5e-20
 Identities = 67/238 (28%), Positives = 114/238 (47%), Gaps = 14/238 (5%)

Query: 137 TSEFFRTLIASTVDYRIKNKVERR---DMIQLLMQLSTE----WTETELAAQLFVFFVAG 189
           T +  R   A+  D +++ K++ R   D + +L+    E     ++ +L A++  F   G
Sbjct: 257 TDQVIRERKAALQDEKVRKKIQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEG 316

Query: 190 FETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYENIGELKYLDCVLNETMRK 249
            +TT + +   ++ +AL P  Q    EE++     +    ++++G++ YL   + E+ R 
Sbjct: 317 HDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKMTYLTMCIKESFRL 376

Query: 250 WSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHMDPIYYEEPEKFIPERF 309
           +     V R  +KP      R       L  G +I   + ++H +   + +PE F   RF
Sbjct: 377 YPPVPQVYRQLSKPVTFVDGRS------LPAGSLISMHIYALHRNSAVWPDPEVFDSLRF 430

Query: 310 LDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVLKCAKTLDPIKM 367
             EN  K  PF FMPF  GPR CIG +FA+ EMK++    +L F+       L PIKM
Sbjct: 431 STENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRL-PIKM 487


>J02871-1|AAA35712.1|  511|Homo sapiens protein ( Human lung
           cytochrome P450 (IV subfamily) BI protein, complete cds.
           ).
          Length = 511

 Score = 97.9 bits (233), Expect = 5e-20
 Identities = 67/238 (28%), Positives = 114/238 (47%), Gaps = 14/238 (5%)

Query: 137 TSEFFRTLIASTVDYRIKNKVERR---DMIQLLMQLSTE----WTETELAAQLFVFFVAG 189
           T +  R   A+  D +++ K++ R   D + +L+    E     ++ +L A++  F   G
Sbjct: 257 TDQVIRERKAALQDEKVRKKIQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEG 316

Query: 190 FETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYENIGELKYLDCVLNETMRK 249
            +TT + +   ++ +AL P  Q    EE++     +    ++++G++ YL   + E+ R 
Sbjct: 317 HDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKMTYLTMCIKESFRL 376

Query: 250 WSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHMDPIYYEEPEKFIPERF 309
           +     V R  +KP      R       L  G +I   + ++H +   + +PE F   RF
Sbjct: 377 YPPVPQVYRQLSKPVTFVDGRS------LPAGSLISMHIYALHRNSAVWPDPEVFDSLRF 430

Query: 310 LDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVLKCAKTLDPIKM 367
             EN  K  PF FMPF  GPR CIG +FA+ EMK++    +L F+       L PIKM
Sbjct: 431 STENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRL-PIKM 487


>DQ518907-1|ABF47106.1|  511|Homo sapiens cytochrome P450, family 4,
           subfamily B, polypeptide 1 protein.
          Length = 511

 Score = 97.9 bits (233), Expect = 5e-20
 Identities = 67/238 (28%), Positives = 114/238 (47%), Gaps = 14/238 (5%)

Query: 137 TSEFFRTLIASTVDYRIKNKVERR---DMIQLLMQLSTE----WTETELAAQLFVFFVAG 189
           T +  R   A+  D +++ K++ R   D + +L+    E     ++ +L A++  F   G
Sbjct: 257 TDQVIRERKAALQDEKVRKKIQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEG 316

Query: 190 FETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYENIGELKYLDCVLNETMRK 249
            +TT + +   ++ +AL P  Q    EE++     +    ++++G++ YL   + E+ R 
Sbjct: 317 HDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKMTYLTMCIKESFRL 376

Query: 250 WSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHMDPIYYEEPEKFIPERF 309
           +     V R  +KP      R       L  G +I   + ++H +   + +PE F   RF
Sbjct: 377 YPPVPQVYRQLSKPVTFVDGRS------LPAGSLISMHIYALHRNSAVWPDPEVFDSLRF 430

Query: 310 LDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVLKCAKTLDPIKM 367
             EN  K  PF FMPF  GPR CIG +FA+ EMK++    +L F+       L PIKM
Sbjct: 431 STENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRL-PIKM 487


>BC017758-1|AAH17758.1|  512|Homo sapiens cytochrome P450, family 4,
           subfamily B, polypeptide 1 protein.
          Length = 512

 Score = 97.9 bits (233), Expect = 5e-20
 Identities = 67/238 (28%), Positives = 114/238 (47%), Gaps = 14/238 (5%)

Query: 137 TSEFFRTLIASTVDYRIKNKVERR---DMIQLLMQLSTE----WTETELAAQLFVFFVAG 189
           T +  R   A+  D +++ K++ R   D + +L+    E     ++ +L A++  F   G
Sbjct: 258 TDQVIRERKAALQDEKVRKKIQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEG 317

Query: 190 FETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYENIGELKYLDCVLNETMRK 249
            +TT + +   ++ +AL P  Q    EE++     +    ++++G++ YL   + E+ R 
Sbjct: 318 HDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKMTYLTMCIKESFRL 377

Query: 250 WSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHMDPIYYEEPEKFIPERF 309
           +     V R  +KP      R       L  G +I   + ++H +   + +PE F   RF
Sbjct: 378 YPPVPQVYRQLSKPVTFVDGRS------LPAGSLISMHIYALHRNSAVWPDPEVFDSLRF 431

Query: 310 LDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVLKCAKTLDPIKM 367
             EN  K  PF FMPF  GPR CIG +FA+ EMK++    +L F+       L PIKM
Sbjct: 432 STENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRL-PIKM 488


>AY151049-1|AAN72312.1|  497|Homo sapiens pulmonary cytochrome P450
           4B1 variant protein.
          Length = 497

 Score = 97.9 bits (233), Expect = 5e-20
 Identities = 67/238 (28%), Positives = 114/238 (47%), Gaps = 14/238 (5%)

Query: 137 TSEFFRTLIASTVDYRIKNKVERR---DMIQLLMQLSTE----WTETELAAQLFVFFVAG 189
           T +  R   A+  D +++ K++ R   D + +L+    E     ++ +L A++  F   G
Sbjct: 243 TDQVIRERKAALQDEKVRKKIQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEG 302

Query: 190 FETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYENIGELKYLDCVLNETMRK 249
            +TT + +   ++ +AL P  Q    EE++     +    ++++G++ YL   + E+ R 
Sbjct: 303 HDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKMTYLTMCIKESFRL 362

Query: 250 WSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHMDPIYYEEPEKFIPERF 309
           +     V R  +KP      R       L  G +I   + ++H +   + +PE F   RF
Sbjct: 363 YPPVPQVYRQLSKPVTFVDGRS------LPAGSLISMHIYALHRNSAVWPDPEVFDSLRF 416

Query: 310 LDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVLKCAKTLDPIKM 367
             EN  K  PF FMPF  GPR CIG +FA+ EMK++    +L F+       L PIKM
Sbjct: 417 STENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRL-PIKM 473


>AY151048-1|AAN72311.1|  512|Homo sapiens pulmonary cytochrome P450
           4B1 protein.
          Length = 512

 Score = 97.9 bits (233), Expect = 5e-20
 Identities = 67/238 (28%), Positives = 114/238 (47%), Gaps = 14/238 (5%)

Query: 137 TSEFFRTLIASTVDYRIKNKVERR---DMIQLLMQLSTE----WTETELAAQLFVFFVAG 189
           T +  R   A+  D +++ K++ R   D + +L+    E     ++ +L A++  F   G
Sbjct: 258 TDQVIRERKAALQDEKVRKKIQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEG 317

Query: 190 FETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYENIGELKYLDCVLNETMRK 249
            +TT + +   ++ +AL P  Q    EE++     +    ++++G++ YL   + E+ R 
Sbjct: 318 HDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKMTYLTMCIKESFRL 377

Query: 250 WSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHMDPIYYEEPEKFIPERF 309
           +     V R  +KP      R       L  G +I   + ++H +   + +PE F   RF
Sbjct: 378 YPPVPQVYRQLSKPVTFVDGRS------LPAGSLISMHIYALHRNSAVWPDPEVFDSLRF 431

Query: 310 LDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVLKCAKTLDPIKM 367
             EN  K  PF FMPF  GPR CIG +FA+ EMK++    +L F+       L PIKM
Sbjct: 432 STENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRL-PIKM 488


>AY064485-1|AAL57720.1|  511|Homo sapiens cytochrome P450 protein.
          Length = 511

 Score = 97.9 bits (233), Expect = 5e-20
 Identities = 67/238 (28%), Positives = 114/238 (47%), Gaps = 14/238 (5%)

Query: 137 TSEFFRTLIASTVDYRIKNKVERR---DMIQLLMQLSTE----WTETELAAQLFVFFVAG 189
           T +  R   A+  D +++ K++ R   D + +L+    E     ++ +L A++  F   G
Sbjct: 257 TDQVIRERKAALQDEKVRKKIQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEG 316

Query: 190 FETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYENIGELKYLDCVLNETMRK 249
            +TT + +   ++ +AL P  Q    EE++     +    ++++G++ YL   + E+ R 
Sbjct: 317 HDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKMTYLTMCIKESFRL 376

Query: 250 WSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHMDPIYYEEPEKFIPERF 309
           +     V R  +KP      R       L  G +I   + ++H +   + +PE F   RF
Sbjct: 377 YPPVPQVYRQLSKPVTFVDGRS------LPAGSLISMHIYALHRNSAVWPDPEVFDSLRF 430

Query: 310 LDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVLKCAKTLDPIKM 367
             EN  K  PF FMPF  GPR CIG +FA+ EMK++    +L F+       L PIKM
Sbjct: 431 STENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRL-PIKM 487


>AL593856-7|CAI16983.1|  497|Homo sapiens cytochrome P450, family 4,
           subfamily B, polypeptide 1 protein.
          Length = 497

 Score = 97.9 bits (233), Expect = 5e-20
 Identities = 67/238 (28%), Positives = 114/238 (47%), Gaps = 14/238 (5%)

Query: 137 TSEFFRTLIASTVDYRIKNKVERR---DMIQLLMQLSTE----WTETELAAQLFVFFVAG 189
           T +  R   A+  D +++ K++ R   D + +L+    E     ++ +L A++  F   G
Sbjct: 243 TDQVIRERKAALQDEKVRKKIQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEG 302

Query: 190 FETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYENIGELKYLDCVLNETMRK 249
            +TT + +   ++ +AL P  Q    EE++     +    ++++G++ YL   + E+ R 
Sbjct: 303 HDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKMTYLTMCIKESFRL 362

Query: 250 WSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHMDPIYYEEPEKFIPERF 309
           +     V R  +KP      R       L  G +I   + ++H +   + +PE F   RF
Sbjct: 363 YPPVPQVYRQLSKPVTFVDGRS------LPAGSLISMHIYALHRNSAVWPDPEVFDSLRF 416

Query: 310 LDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVLKCAKTLDPIKM 367
             EN  K  PF FMPF  GPR CIG +FA+ EMK++    +L F+       L PIKM
Sbjct: 417 STENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRL-PIKM 473


>AL593856-6|CAI16982.1|  512|Homo sapiens cytochrome P450, family 4,
           subfamily B, polypeptide 1 protein.
          Length = 512

 Score = 97.9 bits (233), Expect = 5e-20
 Identities = 67/238 (28%), Positives = 114/238 (47%), Gaps = 14/238 (5%)

Query: 137 TSEFFRTLIASTVDYRIKNKVERR---DMIQLLMQLSTE----WTETELAAQLFVFFVAG 189
           T +  R   A+  D +++ K++ R   D + +L+    E     ++ +L A++  F   G
Sbjct: 258 TDQVIRERKAALQDEKVRKKIQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEG 317

Query: 190 FETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYENIGELKYLDCVLNETMRK 249
            +TT + +   ++ +AL P  Q    EE++     +    ++++G++ YL   + E+ R 
Sbjct: 318 HDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKMTYLTMCIKESFRL 377

Query: 250 WSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHMDPIYYEEPEKFIPERF 309
           +     V R  +KP      R       L  G +I   + ++H +   + +PE F   RF
Sbjct: 378 YPPVPQVYRQLSKPVTFVDGRS------LPAGSLISMHIYALHRNSAVWPDPEVFDSLRF 431

Query: 310 LDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVLKCAKTLDPIKM 367
             EN  K  PF FMPF  GPR CIG +FA+ EMK++    +L F+       L PIKM
Sbjct: 432 STENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRL-PIKM 488


>AL593856-5|CAI16981.1|  511|Homo sapiens cytochrome P450, family 4,
           subfamily B, polypeptide 1 protein.
          Length = 511

 Score = 97.9 bits (233), Expect = 5e-20
 Identities = 67/238 (28%), Positives = 114/238 (47%), Gaps = 14/238 (5%)

Query: 137 TSEFFRTLIASTVDYRIKNKVERR---DMIQLLMQLSTE----WTETELAAQLFVFFVAG 189
           T +  R   A+  D +++ K++ R   D + +L+    E     ++ +L A++  F   G
Sbjct: 257 TDQVIRERKAALQDEKVRKKIQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEG 316

Query: 190 FETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYENIGELKYLDCVLNETMRK 249
            +TT + +   ++ +AL P  Q    EE++     +    ++++G++ YL   + E+ R 
Sbjct: 317 HDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKMTYLTMCIKESFRL 376

Query: 250 WSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHMDPIYYEEPEKFIPERF 309
           +     V R  +KP      R       L  G +I   + ++H +   + +PE F   RF
Sbjct: 377 YPPVPQVYRQLSKPVTFVDGRS------LPAGSLISMHIYALHRNSAVWPDPEVFDSLRF 430

Query: 310 LDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVLKCAKTLDPIKM 367
             EN  K  PF FMPF  GPR CIG +FA+ EMK++    +L F+       L PIKM
Sbjct: 431 STENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRL-PIKM 487


>AL356793-4|CAI22559.1|  511|Homo sapiens cytochrome P450, family 4,
           subfamily B, polypeptide 1 protein.
          Length = 511

 Score = 97.9 bits (233), Expect = 5e-20
 Identities = 67/238 (28%), Positives = 114/238 (47%), Gaps = 14/238 (5%)

Query: 137 TSEFFRTLIASTVDYRIKNKVERR---DMIQLLMQLSTE----WTETELAAQLFVFFVAG 189
           T +  R   A+  D +++ K++ R   D + +L+    E     ++ +L A++  F   G
Sbjct: 257 TDQVIRERKAALQDEKVRKKIQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEG 316

Query: 190 FETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYENIGELKYLDCVLNETMRK 249
            +TT + +   ++ +AL P  Q    EE++     +    ++++G++ YL   + E+ R 
Sbjct: 317 HDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKMTYLTMCIKESFRL 376

Query: 250 WSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHMDPIYYEEPEKFIPERF 309
           +     V R  +KP      R       L  G +I   + ++H +   + +PE F   RF
Sbjct: 377 YPPVPQVYRQLSKPVTFVDGRS------LPAGSLISMHIYALHRNSAVWPDPEVFDSLRF 430

Query: 310 LDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVLKCAKTLDPIKM 367
             EN  K  PF FMPF  GPR CIG +FA+ EMK++    +L F+       L PIKM
Sbjct: 431 STENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRL-PIKM 487


>AL356793-3|CAI22557.1|  512|Homo sapiens cytochrome P450, family 4,
           subfamily B, polypeptide 1 protein.
          Length = 512

 Score = 97.9 bits (233), Expect = 5e-20
 Identities = 67/238 (28%), Positives = 114/238 (47%), Gaps = 14/238 (5%)

Query: 137 TSEFFRTLIASTVDYRIKNKVERR---DMIQLLMQLSTE----WTETELAAQLFVFFVAG 189
           T +  R   A+  D +++ K++ R   D + +L+    E     ++ +L A++  F   G
Sbjct: 258 TDQVIRERKAALQDEKVRKKIQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEG 317

Query: 190 FETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYENIGELKYLDCVLNETMRK 249
            +TT + +   ++ +AL P  Q    EE++     +    ++++G++ YL   + E+ R 
Sbjct: 318 HDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKMTYLTMCIKESFRL 377

Query: 250 WSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHMDPIYYEEPEKFIPERF 309
           +     V R  +KP      R       L  G +I   + ++H +   + +PE F   RF
Sbjct: 378 YPPVPQVYRQLSKPVTFVDGRS------LPAGSLISMHIYALHRNSAVWPDPEVFDSLRF 431

Query: 310 LDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVLKCAKTLDPIKM 367
             EN  K  PF FMPF  GPR CIG +FA+ EMK++    +L F+       L PIKM
Sbjct: 432 STENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRL-PIKM 488


>AL356793-2|CAI22558.1|  497|Homo sapiens cytochrome P450, family 4,
           subfamily B, polypeptide 1 protein.
          Length = 497

 Score = 97.9 bits (233), Expect = 5e-20
 Identities = 67/238 (28%), Positives = 114/238 (47%), Gaps = 14/238 (5%)

Query: 137 TSEFFRTLIASTVDYRIKNKVERR---DMIQLLMQLSTE----WTETELAAQLFVFFVAG 189
           T +  R   A+  D +++ K++ R   D + +L+    E     ++ +L A++  F   G
Sbjct: 243 TDQVIRERKAALQDEKVRKKIQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEG 302

Query: 190 FETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYENIGELKYLDCVLNETMRK 249
            +TT + +   ++ +AL P  Q    EE++     +    ++++G++ YL   + E+ R 
Sbjct: 303 HDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKMTYLTMCIKESFRL 362

Query: 250 WSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHMDPIYYEEPEKFIPERF 309
           +     V R  +KP      R       L  G +I   + ++H +   + +PE F   RF
Sbjct: 363 YPPVPQVYRQLSKPVTFVDGRS------LPAGSLISMHIYALHRNSAVWPDPEVFDSLRF 416

Query: 310 LDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVLKCAKTLDPIKM 367
             EN  K  PF FMPF  GPR CIG +FA+ EMK++    +L F+       L PIKM
Sbjct: 417 STENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRL-PIKM 473


>AF491285-1|AAM09532.1|  511|Homo sapiens cytochrome P450 protein.
          Length = 511

 Score = 97.9 bits (233), Expect = 5e-20
 Identities = 67/238 (28%), Positives = 114/238 (47%), Gaps = 14/238 (5%)

Query: 137 TSEFFRTLIASTVDYRIKNKVERR---DMIQLLMQLSTE----WTETELAAQLFVFFVAG 189
           T +  R   A+  D +++ K++ R   D + +L+    E     ++ +L A++  F   G
Sbjct: 257 TDQVIRERKAALQDEKVRKKIQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEG 316

Query: 190 FETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYENIGELKYLDCVLNETMRK 249
            +TT + +   ++ +AL P  Q    EE++     +    ++++G++ YL   + E+ R 
Sbjct: 317 HDTTTSGISWFLYCIALYPEHQHRCREEVREILGDQDFFQWDDLGKMTYLTMCIKESFRL 376

Query: 250 WSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHMDPIYYEEPEKFIPERF 309
           +     V R  +KP      R       L  G +I   + ++H +   + +PE F   RF
Sbjct: 377 YPPVPQVYRQLSKPVTFVDGRS------LPAGSLISMHIYALHRNSAVWPDPEVFDSLRF 430

Query: 310 LDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVLKCAKTLDPIKM 367
             EN  K  PF FMPF  GPR CIG +FA+ EMK++    +L F+       L PIKM
Sbjct: 431 STENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRL-PIKM 487


>AY064486-1|AAL57721.1|  511|Homo sapiens cytochrome P450 protein.
          Length = 511

 Score = 97.5 bits (232), Expect = 7e-20
 Identities = 67/238 (28%), Positives = 113/238 (47%), Gaps = 14/238 (5%)

Query: 137 TSEFFRTLIASTVDYRIKNKVERR---DMIQLLMQLSTE----WTETELAAQLFVFFVAG 189
           T +  R   A+  D +++ K++ R   D + +L+    E     ++ +L A++  F   G
Sbjct: 257 TDQVIRERKAALQDEKVRKKIQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEG 316

Query: 190 FETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYENIGELKYLDCVLNETMRK 249
            +TT   +   ++ +AL P  Q    EE++     +    ++++G++ YL   + E+ R 
Sbjct: 317 HDTTTGGISWFLYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKMTYLTMCIKESFRL 376

Query: 250 WSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHMDPIYYEEPEKFIPERF 309
           +     V R  +KP      R       L  G +I   + ++H +   + +PE F   RF
Sbjct: 377 YPPVPQVYRQLSKPVTFVDGRS------LPAGSLISMHIYALHRNSAVWPDPEVFDSLRF 430

Query: 310 LDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVLKCAKTLDPIKM 367
             EN  K  PF FMPF  GPR CIG +FA+ EMK++    +L F+       L PIKM
Sbjct: 431 STENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRL-PIKM 487


>AY792513-1|AAV40834.1|  520|Homo sapiens cytochrome P450, family 4,
           subfamily F, polypeptide 3 protein.
          Length = 520

 Score = 94.7 bits (225), Expect = 5e-19
 Identities = 64/223 (28%), Positives = 110/223 (49%), Gaps = 14/223 (6%)

Query: 142 RTLIASTVD--YRIKNKVERRDMIQLLMQLSTE----WTETELAAQLFVFFVAGFETTGN 195
           RTL +  VD   + K K +  D I +L+    E     ++ ++ A+   F   G +TT +
Sbjct: 276 RTLPSQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTAS 335

Query: 196 TLINCIHELALSPHIQDILYEELKAFKETKG--NLVYENIGELKYLDCVLNETMRKWSAA 253
            L   ++ LA  P  Q+   +E++   + +    + ++++ +L +L   + E++R     
Sbjct: 336 GLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPV 395

Query: 254 IFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHMDPIYYEEPEKFIPERFLDEN 313
             V R CT+  VLP  R       +  G +   +V   H +P  + +PE + P RF  +N
Sbjct: 396 PAVSRCCTQDIVLPDGRV------IPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPKN 449

Query: 314 KHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVL 356
             +  P  F+PF  GPR CIG  FA+ EMK++L   +L F+VL
Sbjct: 450 IKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLGLTLLRFRVL 492


>AF054821-1|AAC08589.1|  520|Homo sapiens cytochrome P-450 protein.
          Length = 520

 Score = 94.7 bits (225), Expect = 5e-19
 Identities = 64/223 (28%), Positives = 110/223 (49%), Gaps = 14/223 (6%)

Query: 142 RTLIASTVD--YRIKNKVERRDMIQLLMQLSTE----WTETELAAQLFVFFVAGFETTGN 195
           RTL +  VD   + K K +  D I +L+    E     ++ ++ A+   F   G +TT +
Sbjct: 276 RTLPSQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTAS 335

Query: 196 TLINCIHELALSPHIQDILYEELKAFKETKG--NLVYENIGELKYLDCVLNETMRKWSAA 253
            L   ++ LA  P  Q+   +E++   + +    + ++++ +L +L   + E++R     
Sbjct: 336 GLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPV 395

Query: 254 IFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHMDPIYYEEPEKFIPERFLDEN 313
             V R CT+  VLP  R       +  G +   +V   H +P  + +PE + P RF  +N
Sbjct: 396 PAVSRCCTQDIVLPDGRV------IPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPKN 449

Query: 314 KHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVL 356
             +  P  F+PF  GPR CIG  FA+ EMK++L   +L F+VL
Sbjct: 450 IKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLGLTLLRFRVL 492


>D12620-1|BAA02144.1|  520|Homo sapiens cytochrome P-450LTBV
           protein.
          Length = 520

 Score = 93.9 bits (223), Expect = 9e-19
 Identities = 64/223 (28%), Positives = 110/223 (49%), Gaps = 14/223 (6%)

Query: 142 RTLIASTVD--YRIKNKVERRDMIQLLMQLSTE----WTETELAAQLFVFFVAGFETTGN 195
           RTL +  VD   + K K +  D I +L+    E     ++ ++ A+   F   G +TT +
Sbjct: 276 RTLPSQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTAS 335

Query: 196 TLINCIHELALSPHIQDILYEELKAFKETKG--NLVYENIGELKYLDCVLNETMRKWSAA 253
            L   ++ LA  P  Q+   +E++   + +    + ++++ +L +L   + E++R     
Sbjct: 336 GLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPV 395

Query: 254 IFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHMDPIYYEEPEKFIPERFLDEN 313
             V R CT+  VLP  R       +  G +   +V   H +P  + +PE + P RF  +N
Sbjct: 396 PAVSRCCTQDIVLPDGRV------IPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPKN 449

Query: 314 KHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVL 356
             +  P  F+PF  GPR CIG  FA+ EMK++L   +L F+VL
Sbjct: 450 IKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLGLTLLAFRVL 492


>BC060857-1|AAH60857.1|  525|Homo sapiens cytochrome P450, family 4,
           subfamily V, polypeptide 2 protein.
          Length = 525

 Score = 93.9 bits (223), Expect = 9e-19
 Identities = 58/204 (28%), Positives = 105/204 (51%), Gaps = 12/204 (5%)

Query: 155 NKVERRDMIQLLMQLSTE----WTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHI 210
           +K +RR  + LL+ ++ +     +  ++  ++  F   G +TT   +   ++ L  +P +
Sbjct: 292 SKNKRRAFLDLLLSVTDDEGNRLSHEDIREEVDTFMFEGHDTTAAAINWSLYLLGSNPEV 351

Query: 211 QDILYEELK-AFKETKGNLVYENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPP 269
           Q  +  EL   F ++      E++ +L+YL+CV+ ET+R + +     R  ++   +   
Sbjct: 352 QKKVDHELDDVFGKSDRPATVEDLKKLRYLECVIKETLRLFPSVPLFARSVSEDCEVAGY 411

Query: 270 REGGKPCQLKPGEVIYNTVNSIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGP 329
           R       LK  E +     ++H DP Y+  PE+F PERF  EN     P+ ++PF  GP
Sbjct: 412 RV------LKGTEAVIIPY-ALHRDPRYFPNPEEFQPERFFPENAQGRHPYAYVPFSAGP 464

Query: 330 RYCIGSRFALMEMKILLFRLMLNF 353
           R CIG +FA+ME K +L  ++ +F
Sbjct: 465 RNCIGQKFAVMEEKTILSCILRHF 488


>AY422002-1|AAR31180.1|  525|Homo sapiens cytochrome P450 4V2
           protein.
          Length = 525

 Score = 93.9 bits (223), Expect = 9e-19
 Identities = 58/204 (28%), Positives = 105/204 (51%), Gaps = 12/204 (5%)

Query: 155 NKVERRDMIQLLMQLSTE----WTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHI 210
           +K +RR  + LL+ ++ +     +  ++  ++  F   G +TT   +   ++ L  +P +
Sbjct: 292 SKNKRRAFLDLLLSVTDDEGNRLSHEDIREEVDTFMFEGHDTTAAAINWSLYLLGSNPEV 351

Query: 211 QDILYEELK-AFKETKGNLVYENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPP 269
           Q  +  EL   F ++      E++ +L+YL+CV+ ET+R + +     R  ++   +   
Sbjct: 352 QKKVDHELDDVFGKSDRPATVEDLKKLRYLECVIKETLRLFPSVPLFARSVSEDCEVAGY 411

Query: 270 REGGKPCQLKPGEVIYNTVNSIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGP 329
           R       LK  E +     ++H DP Y+  PE+F PERF  EN     P+ ++PF  GP
Sbjct: 412 RV------LKGTEAVIIPY-ALHRDPRYFPNPEEFQPERFFPENAQGRHPYAYVPFSAGP 464

Query: 330 RYCIGSRFALMEMKILLFRLMLNF 353
           R CIG +FA+ME K +L  ++ +F
Sbjct: 465 RNCIGQKFAVMEEKTILSCILRHF 488


>AK126473-1|BAC86562.1|  503|Homo sapiens protein ( Homo sapiens
           cDNA FLJ44509 fis, clone UTERU3001585, weakly  similar
           to Cytochrome P450 4c3 (EC 1.14.-.-). ).
          Length = 503

 Score = 93.9 bits (223), Expect = 9e-19
 Identities = 58/204 (28%), Positives = 105/204 (51%), Gaps = 12/204 (5%)

Query: 155 NKVERRDMIQLLMQLSTE----WTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHI 210
           +K +RR  + LL+ ++ +     +  ++  ++  F   G +TT   +   ++ L  +P +
Sbjct: 270 SKNKRRAFLDLLLSVTDDEGNRLSHEDIREEVDTFMFEGHDTTAAAINWSLYLLGSNPEV 329

Query: 211 QDILYEELK-AFKETKGNLVYENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPP 269
           Q  +  EL   F ++      E++ +L+YL+CV+ ET+R + +     R  ++   +   
Sbjct: 330 QKKVDHELDDVFGKSDRPATVEDLKKLRYLECVIKETLRLFPSVPLFARSVSEDCEVAGY 389

Query: 270 REGGKPCQLKPGEVIYNTVNSIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGP 329
           R       LK  E +     ++H DP Y+  PE+F PERF  EN     P+ ++PF  GP
Sbjct: 390 RV------LKGTEAVIIPY-ALHRDPRYFPNPEEFQPERFFPENAQGRHPYAYVPFSAGP 442

Query: 330 RYCIGSRFALMEMKILLFRLMLNF 353
           R CIG +FA+ME K +L  ++ +F
Sbjct: 443 RNCIGQKFAVMEEKTILSCILRHF 466


>AK122600-1|BAC85487.1|  525|Homo sapiens protein ( Homo sapiens
           cDNA FLJ16007 fis, clone KIDNE2006580, weakly  similar
           to CYTOCHROME P450 4C1 (EC 1.14.14.1). ).
          Length = 525

 Score = 93.9 bits (223), Expect = 9e-19
 Identities = 58/204 (28%), Positives = 105/204 (51%), Gaps = 12/204 (5%)

Query: 155 NKVERRDMIQLLMQLSTE----WTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHI 210
           +K +RR  + LL+ ++ +     +  ++  ++  F   G +TT   +   ++ L  +P +
Sbjct: 292 SKNKRRAFLDLLLSVTDDEGNRLSHEDIREEVDTFMFEGHDTTAAAINWSLYLLGSNPEV 351

Query: 211 QDILYEELK-AFKETKGNLVYENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPP 269
           Q  +  EL   F ++      E++ +L+YL+CV+ ET+R + +     R  ++   +   
Sbjct: 352 QKKVDHELDDVFGKSDRPATVEDLKKLRYLECVIKETLRLFPSVPLFARSVSEDCEVAGY 411

Query: 270 REGGKPCQLKPGEVIYNTVNSIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGP 329
           R       LK  E +     ++H DP Y+  PE+F PERF  EN     P+ ++PF  GP
Sbjct: 412 RV------LKGTEAVIIPY-ALHRDPRYFPNPEEFQPERFFPENAQGRHPYAYVPFSAGP 464

Query: 330 RYCIGSRFALMEMKILLFRLMLNF 353
           R CIG +FA+ME K +L  ++ +F
Sbjct: 465 RNCIGQKFAVMEEKTILSCILRHF 488


>AB002461-1|BAA25991.1|  520|Homo sapiens leukotriene B4
           omega-hydroxylase protein.
          Length = 520

 Score = 93.9 bits (223), Expect = 9e-19
 Identities = 64/223 (28%), Positives = 110/223 (49%), Gaps = 14/223 (6%)

Query: 142 RTLIASTVD--YRIKNKVERRDMIQLLMQLSTE----WTETELAAQLFVFFVAGFETTGN 195
           RTL +  VD   + K K +  D I +L+    E     ++ ++ A+   F   G +TT +
Sbjct: 276 RTLPSQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTAS 335

Query: 196 TLINCIHELALSPHIQDILYEELKAFKETKG--NLVYENIGELKYLDCVLNETMRKWSAA 253
            L   ++ LA  P  Q+   +E++   + +    + ++++ +L +L   + E++R     
Sbjct: 336 GLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPV 395

Query: 254 IFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHMDPIYYEEPEKFIPERFLDEN 313
             V R CT+  VLP  R       +  G +   +V   H +P  + +PE + P RF  +N
Sbjct: 396 PAVSRCCTQDIVLPDGRV------IPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPKN 449

Query: 314 KHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVL 356
             +  P  F+PF  GPR CIG  FA+ EMK++L   +L F+VL
Sbjct: 450 IKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLGLTLLAFRVL 492


>AB002454-1|BAA25990.1|  520|Homo sapiens leukotriene B4
           omega-hydroxylase protein.
          Length = 520

 Score = 93.9 bits (223), Expect = 9e-19
 Identities = 64/223 (28%), Positives = 110/223 (49%), Gaps = 14/223 (6%)

Query: 142 RTLIASTVD--YRIKNKVERRDMIQLLMQLSTE----WTETELAAQLFVFFVAGFETTGN 195
           RTL +  VD   + K K +  D I +L+    E     ++ ++ A+   F   G +TT +
Sbjct: 276 RTLPSQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTAS 335

Query: 196 TLINCIHELALSPHIQDILYEELKAFKETKG--NLVYENIGELKYLDCVLNETMRKWSAA 253
            L   ++ LA  P  Q+   +E++   + +    + ++++ +L +L   + E++R     
Sbjct: 336 GLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPV 395

Query: 254 IFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHMDPIYYEEPEKFIPERFLDEN 313
             V R CT+  VLP  R       +  G +   +V   H +P  + +PE + P RF  +N
Sbjct: 396 PAVSRCCTQDIVLPDGRV------IPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPKN 449

Query: 314 KHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVL 356
             +  P  F+PF  GPR CIG  FA+ EMK++L   +L F+VL
Sbjct: 450 IKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLGLTLLAFRVL 492


>U02388-1|AAC50052.2|  520|Homo sapiens cytochrome P450 4F2 protein.
          Length = 520

 Score = 91.9 bits (218), Expect = 4e-18
 Identities = 63/223 (28%), Positives = 108/223 (48%), Gaps = 14/223 (6%)

Query: 142 RTLIASTVD--YRIKNKVERRDMIQLLMQLSTE----WTETELAAQLFVFFVAGFETTGN 195
           RTL +  VD   + K K +  D I +L+    E     ++ ++ A+   F   G +TT +
Sbjct: 276 RTLPSQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTAS 335

Query: 196 TLINCIHELALSPHIQDILYEELKAFKETKG--NLVYENIGELKYLDCVLNETMRKWSAA 253
            L   ++ LA  P  Q+   +E++   + +    + ++++  L +L   + E++R     
Sbjct: 336 VLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPFLTMCMKESLRVHPPV 395

Query: 254 IFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHMDPIYYEEPEKFIPERFLDEN 313
             + R  T+  VLP  R       +  G +   +V   H +P  + +PE + P RF  EN
Sbjct: 396 PVISRHVTQDIVLPDGRV------IPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPEN 449

Query: 314 KHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVL 356
             +  P  F+PF  GPR CIG  FA+ EMK++L   +L F+VL
Sbjct: 450 IKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLALTLLRFRVL 492


>AF280110-1|AAG33011.1|  420|Homo sapiens cytochrome P450 subfamily
           IIIA polypeptide 43 protein.
          Length = 420

 Score = 91.9 bits (218), Expect = 4e-18
 Identities = 62/200 (31%), Positives = 99/200 (49%), Gaps = 19/200 (9%)

Query: 121 FPSLS---KKLGFTIIPKSTSEFFRTLIASTVDYRIKNKVERR-DMIQLLM--QLSTEW- 173
           FP L+   + L   + PK  + F +  I    + R+K+K + R D  Q ++  Q S E  
Sbjct: 226 FPFLTPVFEALNIGLFPKDVTHFLKNSIERMKESRLKDKQKHRVDFFQQMIDSQNSKETK 285

Query: 174 -----TETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNL 228
                ++ EL AQ  +   A ++TT  TL   ++ELA  P +Q  L EE+ A    K  +
Sbjct: 286 SHKALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAPV 345

Query: 229 VYENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTV 288
            Y+ + +++YLD V+NET+R +     V R+C K   +           +  G  +   +
Sbjct: 346 TYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEI-------NGVFIPKGLAVMVPI 398

Query: 289 NSIHMDPIYYEEPEKFIPER 308
            ++H DP Y+ EPEKF PER
Sbjct: 399 YALHHDPKYWTEPEKFCPER 418



 Score = 73.7 bits (173), Expect = 1e-12
 Identities = 41/100 (41%), Positives = 61/100 (61%), Gaps = 7/100 (7%)

Query: 23  NERYV---GFTDGVCPGIFIRDPEIIKHVTVKE-FDHFVNNKDLSPEGEESILKNSLIML 78
           NE+Y    G  +G  P + I DP++IK V VKE +  F N   L P G    LK++L   
Sbjct: 65  NEKYGEMWGLYEGQQPMLVIMDPDMIKTVLVKECYSVFTNQMPLGPMG---FLKSALSFA 121

Query: 79  KDEKWRKMRAALSPAFTASKMREMVPLITEISHNIVEYLK 118
           +DE+W+++R  LSPAFT+ K +EMVP+I++    +V  L+
Sbjct: 122 EDEEWKRIRTLLSPAFTSVKFKEMVPIISQCGDMLVRSLR 161


>D26480-1|BAA05490.1|  520|Homo sapiens leukotriene B4
           omega-hydroxylase protein.
          Length = 520

 Score = 91.1 bits (216), Expect = 6e-18
 Identities = 63/223 (28%), Positives = 108/223 (48%), Gaps = 14/223 (6%)

Query: 142 RTLIASTVD--YRIKNKVERRDMIQLLMQLSTE----WTETELAAQLFVFFVAGFETTGN 195
           RTL +  VD   + K K +  D I +L+    E     ++ ++ A+   F   G +TT +
Sbjct: 276 RTLPSQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTAS 335

Query: 196 TLINCIHELALSPHIQDILYEELKAFKETKG--NLVYENIGELKYLDCVLNETMRKWSAA 253
            L   ++ LA  P  Q+   +E++   + +    + ++++  L +L   + E++R     
Sbjct: 336 GLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPV 395

Query: 254 IFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHMDPIYYEEPEKFIPERFLDEN 313
             + R  T+  VLP  R       +  G +   +V   H +P  + +PE + P RF  EN
Sbjct: 396 PVISRHVTQDIVLPDGRV------IPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPEN 449

Query: 314 KHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVL 356
             +  P  F+PF  GPR CIG  FA+ EMK++L   +L F+VL
Sbjct: 450 IKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLALTLLRFRVL 492


>BC067440-1|AAH67440.1|  520|Homo sapiens cytochrome P450, family 4,
           subfamily F, polypeptide 2 protein.
          Length = 520

 Score = 91.1 bits (216), Expect = 6e-18
 Identities = 63/223 (28%), Positives = 108/223 (48%), Gaps = 14/223 (6%)

Query: 142 RTLIASTVD--YRIKNKVERRDMIQLLMQLSTE----WTETELAAQLFVFFVAGFETTGN 195
           RTL +  VD   + K K +  D I +L+    E     ++ ++ A+   F   G +TT +
Sbjct: 276 RTLPSQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTAS 335

Query: 196 TLINCIHELALSPHIQDILYEELKAFKETKG--NLVYENIGELKYLDCVLNETMRKWSAA 253
            L   ++ LA  P  Q+   +E++   + +    + ++++  L +L   + E++R     
Sbjct: 336 GLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPV 395

Query: 254 IFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHMDPIYYEEPEKFIPERFLDEN 313
             + R  T+  VLP  R       +  G +   +V   H +P  + +PE + P RF  EN
Sbjct: 396 PVISRHVTQDIVLPDGRV------IPKGIICLISVFGTHHNPAMWPDPEVYDPFRFDPEN 449

Query: 314 KHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVL 356
             +  P  F+PF  GPR CIG  FA+ EMK++L   +L F+VL
Sbjct: 450 IKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLALTLLRFRVL 492


>BC067439-1|AAH67439.1|  520|Homo sapiens cytochrome P450, family 4,
           subfamily F, polypeptide 2 protein.
          Length = 520

 Score = 91.1 bits (216), Expect = 6e-18
 Identities = 63/223 (28%), Positives = 108/223 (48%), Gaps = 14/223 (6%)

Query: 142 RTLIASTVD--YRIKNKVERRDMIQLLMQLSTE----WTETELAAQLFVFFVAGFETTGN 195
           RTL +  VD   + K K +  D I +L+    E     ++ ++ A+   F   G +TT +
Sbjct: 276 RTLPSQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTAS 335

Query: 196 TLINCIHELALSPHIQDILYEELKAFKETKG--NLVYENIGELKYLDCVLNETMRKWSAA 253
            L   ++ LA  P  Q+   +E++   + +    + ++++  L +L   + E++R     
Sbjct: 336 GLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPV 395

Query: 254 IFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHMDPIYYEEPEKFIPERFLDEN 313
             + R  T+  VLP  R       +  G +   +V   H +P  + +PE + P RF  EN
Sbjct: 396 PVISRHVTQDIVLPDGRV------IPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPEN 449

Query: 314 KHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVL 356
             +  P  F+PF  GPR CIG  FA+ EMK++L   +L F+VL
Sbjct: 450 IKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLALTLLRFRVL 492


>BC067437-1|AAH67437.1|  520|Homo sapiens cytochrome P450, family 4,
           subfamily F, polypeptide 2 protein.
          Length = 520

 Score = 91.1 bits (216), Expect = 6e-18
 Identities = 63/223 (28%), Positives = 108/223 (48%), Gaps = 14/223 (6%)

Query: 142 RTLIASTVD--YRIKNKVERRDMIQLLMQLSTE----WTETELAAQLFVFFVAGFETTGN 195
           RTL +  VD   + K K +  D I +L+    E     ++ ++ A+   F   G +TT +
Sbjct: 276 RTLPSQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTAS 335

Query: 196 TLINCIHELALSPHIQDILYEELKAFKETKG--NLVYENIGELKYLDCVLNETMRKWSAA 253
            L   ++ LA  P  Q+   +E++   + +    + ++++  L +L   + E++R     
Sbjct: 336 GLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPV 395

Query: 254 IFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHMDPIYYEEPEKFIPERFLDEN 313
             + R  T+  VLP  R       +  G +   +V   H +P  + +PE + P RF  EN
Sbjct: 396 PVISRHVTQDIVLPDGRV------IPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPEN 449

Query: 314 KHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVL 356
             +  P  F+PF  GPR CIG  FA+ EMK++L   +L F+VL
Sbjct: 450 IKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLALTLLRFRVL 492


>AF467894-1|AAL67578.1|  520|Homo sapiens cytochrome P450, subfamily
           IVF, polypeptide 2 protein.
          Length = 520

 Score = 91.1 bits (216), Expect = 6e-18
 Identities = 63/223 (28%), Positives = 108/223 (48%), Gaps = 14/223 (6%)

Query: 142 RTLIASTVD--YRIKNKVERRDMIQLLMQLSTE----WTETELAAQLFVFFVAGFETTGN 195
           RTL +  VD   + K K +  D I +L+    E     ++ ++ A+   F   G +TT +
Sbjct: 276 RTLPSQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTAS 335

Query: 196 TLINCIHELALSPHIQDILYEELKAFKETKG--NLVYENIGELKYLDCVLNETMRKWSAA 253
            L   ++ LA  P  Q+   +E++   + +    + ++++  L +L   + E++R     
Sbjct: 336 GLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPV 395

Query: 254 IFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHMDPIYYEEPEKFIPERFLDEN 313
             + R  T+  VLP  R       +  G +   +V   H +P  + +PE + P RF  EN
Sbjct: 396 PVISRHVTQDIVLPDGRV------IPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPEN 449

Query: 314 KHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVL 356
             +  P  F+PF  GPR CIG  FA+ EMK++L   +L F+VL
Sbjct: 450 IKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLALTLLRFRVL 492


>AC005336-1|AAC27730.1|  520|Homo sapiens CYP4F2 protein.
          Length = 520

 Score = 91.1 bits (216), Expect = 6e-18
 Identities = 63/223 (28%), Positives = 108/223 (48%), Gaps = 14/223 (6%)

Query: 142 RTLIASTVD--YRIKNKVERRDMIQLLMQLSTE----WTETELAAQLFVFFVAGFETTGN 195
           RTL +  VD   + K K +  D I +L+    E     ++ ++ A+   F   G +TT +
Sbjct: 276 RTLPSQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTAS 335

Query: 196 TLINCIHELALSPHIQDILYEELKAFKETKG--NLVYENIGELKYLDCVLNETMRKWSAA 253
            L   ++ LA  P  Q+   +E++   + +    + ++++  L +L   + E++R     
Sbjct: 336 GLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPV 395

Query: 254 IFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHMDPIYYEEPEKFIPERFLDEN 313
             + R  T+  VLP  R       +  G +   +V   H +P  + +PE + P RF  EN
Sbjct: 396 PVISRHVTQDIVLPDGRV------IPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPEN 449

Query: 314 KHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVL 356
             +  P  F+PF  GPR CIG  FA+ EMK++L   +L F+VL
Sbjct: 450 IKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLALTLLRFRVL 492


>AB015306-1|BAA75823.1|  520|Homo sapiens Leukotriene B4
           omega-hydroxylase protein.
          Length = 520

 Score = 91.1 bits (216), Expect = 6e-18
 Identities = 63/223 (28%), Positives = 108/223 (48%), Gaps = 14/223 (6%)

Query: 142 RTLIASTVD--YRIKNKVERRDMIQLLMQLSTE----WTETELAAQLFVFFVAGFETTGN 195
           RTL +  VD   + K K +  D I +L+    E     ++ ++ A+   F   G +TT +
Sbjct: 276 RTLPSQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTAS 335

Query: 196 TLINCIHELALSPHIQDILYEELKAFKETKG--NLVYENIGELKYLDCVLNETMRKWSAA 253
            L   ++ LA  P  Q+   +E++   + +    + ++++  L +L   + E++R     
Sbjct: 336 GLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPV 395

Query: 254 IFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHMDPIYYEEPEKFIPERFLDEN 313
             + R  T+  VLP  R       +  G +   +V   H +P  + +PE + P RF  EN
Sbjct: 396 PVISRHVTQDIVLPDGRV------IPKGIICLISVFGTHHNPAMWPDPEVYDPFRFDPEN 449

Query: 314 KHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVL 356
             +  P  F+PF  GPR CIG  FA+ EMK++L   +L F+VL
Sbjct: 450 IKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLALTLLRFRVL 492


>BC132767-1|AAI32768.1|  544|Homo sapiens cytochrome P450, family 2,
           subfamily U, polypeptide 1 protein.
          Length = 544

 Score = 90.6 bits (215), Expect = 8e-18
 Identities = 50/169 (29%), Positives = 90/169 (53%), Gaps = 8/169 (4%)

Query: 186 FVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYENIGELKYLDCVLNE 245
           F+AG +TT N+L+ C+  ++L+P +Q+ ++EE++            +  ++ Y +  + E
Sbjct: 350 FIAGTDTTTNSLLWCLLYMSLNPDVQEKVHEEIERVIGANRAPSLTDKAQMPYTEATIME 409

Query: 246 TMRKWSAA-IFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHMDPIYYEEPEKF 304
             R      + +  + ++  VL       +   +  G +I   + S+H DP  +E+PE F
Sbjct: 410 VQRLTVVVPLAIPHMTSENTVL-------QGYTIPKGTLILPNLWSVHRDPAIWEKPEDF 462

Query: 305 IPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNF 353
            P RFLD+    IK  TF+PFG+G R C+G + A ME+ ++   LM +F
Sbjct: 463 YPNRFLDDQGQLIKKETFIPFGIGKRVCMGEQLAKMELFLMFVSLMQSF 511


>AY343323-1|AAQ21380.1|  544|Homo sapiens cytochrome P450 protein.
          Length = 544

 Score = 90.6 bits (215), Expect = 8e-18
 Identities = 50/169 (29%), Positives = 90/169 (53%), Gaps = 8/169 (4%)

Query: 186 FVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYENIGELKYLDCVLNE 245
           F+AG +TT N+L+ C+  ++L+P +Q+ ++EE++            +  ++ Y +  + E
Sbjct: 350 FIAGTDTTTNSLLWCLLYMSLNPDVQEKVHEEIERVIGANRAPSLTDKAQMPYTEATIME 409

Query: 246 TMRKWSAA-IFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHMDPIYYEEPEKF 304
             R      + +  + ++  VL       +   +  G +I   + S+H DP  +E+PE F
Sbjct: 410 VQRLTVVVPLAIPHMTSENTVL-------QGYTIPKGTLILPNLWSVHRDPAIWEKPEDF 462

Query: 305 IPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNF 353
            P RFLD+    IK  TF+PFG+G R C+G + A ME+ ++   LM +F
Sbjct: 463 YPNRFLDDQGQLIKKETFIPFGIGKRVCMGEQLAKMELFLMFVSLMQSF 511


>BC022539-1|AAH22539.1|  500|Homo sapiens cytochrome P450, family
           46, subfamily A, polypeptide 1 protein.
          Length = 500

 Score = 84.2 bits (199), Expect = 7e-16
 Identities = 58/175 (33%), Positives = 94/175 (53%), Gaps = 13/175 (7%)

Query: 185 FFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYENIGELKYLDCVLN 244
           FF+AG ET+ N L   + EL+  P I   L  E+     +K  L +E++G L+YL  VL 
Sbjct: 299 FFIAGHETSANHLAFTVMELSRQPEIVARLQAEVDEVIGSKRYLDFEDLGRLQYLSQVLK 358

Query: 245 ETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHMDPIYYEEPEKF 304
           E++R +  A    R+  +  ++   R  G         ++++T     MD  Y+E+P  F
Sbjct: 359 ESLRLYPPAWGTFRLLEEETLIDGVRVPGNT------PLLFSTYVMGRMD-TYFEDPLTF 411

Query: 305 IPERFLDENKHKIKP-FTFMPFGVGPRYCIGSRFALMEMKILLFRLM--LNFKVL 356
            P+RF        KP FT+ PF +G R CIG +FA ME+K+++ +L+  L F+++
Sbjct: 412 NPDRF---GPGAPKPRFTYFPFSLGHRSCIGQQFAQMEVKVVMAKLLQRLEFRLV 463


>AF094480-1|AAD41244.1|  500|Homo sapiens cholesterol 24-hydroxylase
           protein.
          Length = 500

 Score = 84.2 bits (199), Expect = 7e-16
 Identities = 58/175 (33%), Positives = 94/175 (53%), Gaps = 13/175 (7%)

Query: 185 FFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYENIGELKYLDCVLN 244
           FF+AG ET+ N L   + EL+  P I   L  E+     +K  L +E++G L+YL  VL 
Sbjct: 299 FFIAGHETSANHLAFTVMELSRQPEIVARLQAEVDEVIGSKRYLDFEDLGRLQYLSQVLK 358

Query: 245 ETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHMDPIYYEEPEKF 304
           E++R +  A    R+  +  ++   R  G         ++++T     MD  Y+E+P  F
Sbjct: 359 ESLRLYPPAWGTFRLLEEETLIDGVRVPGNT------PLLFSTYVMGRMD-TYFEDPLTF 411

Query: 305 IPERFLDENKHKIKP-FTFMPFGVGPRYCIGSRFALMEMKILLFRLM--LNFKVL 356
            P+RF        KP FT+ PF +G R CIG +FA ME+K+++ +L+  L F+++
Sbjct: 412 NPDRF---GPGAPKPRFTYFPFSLGHRSCIGQQFAQMEVKVVMAKLLQRLEFRLV 463


>BC100982-1|AAI00983.1|  280|Homo sapiens CYP3A43 protein protein.
          Length = 280

 Score = 83.8 bits (198), Expect = 9e-16
 Identities = 45/135 (33%), Positives = 71/135 (52%), Gaps = 7/135 (5%)

Query: 174 TETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYENI 233
           ++ EL AQ  +   A ++TT  TL   ++ELA  P +Q  L EE+ A    K  + Y+ +
Sbjct: 151 SDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAPVTYDAL 210

Query: 234 GELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHM 293
            +++YLD V+NET+R +     V R+C K   +           +  G  +   + ++H 
Sbjct: 211 VQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEI-------NGVFIPKGLAVMVPIYALHH 263

Query: 294 DPIYYEEPEKFIPER 308
           DP Y+ EPEKF PER
Sbjct: 264 DPKYWTEPEKFCPER 278


>L13286-1|AAA62379.1|  513|Homo sapiens 1,25-dihydroxyvitamin D3
           24-hydroxylase protein.
          Length = 513

 Score = 81.4 bits (192), Expect = 5e-15
 Identities = 57/194 (29%), Positives = 95/194 (48%), Gaps = 10/194 (5%)

Query: 174 TETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYENI 233
           ++ EL A +    +A  ETT N+L+  ++ L+ +P +Q  L +E+++          E++
Sbjct: 311 SKKELYAAVTELQLAAVETTANSLMWILYNLSRNPQVQQKLLKEIQSVLPENQRPREEDL 370

Query: 234 GELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHM 293
             + YL   L E+MR      F  R   K  VL      G+   L  G V+      +  
Sbjct: 371 RNMPYLKACLKESMRLTPGVPFTTRTLDKATVL------GEYA-LPKGTVLMLNTQVLGS 423

Query: 294 DPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNF 353
               +E+  +F PER+L E K KI PF  +PFGVG R CIG R A +++ + L  ++  +
Sbjct: 424 SEDNFEDSSQFRPERWLQE-KEKINPFAHLPFGVGKRMCIGRRLAELQLHLALCWIVRKY 482

Query: 354 KVLKCAKTLDPIKM 367
            +   A   +P++M
Sbjct: 483 DIQ--ATDNEPVEM 494


>S67623-1|AAB29308.1|  257|Homo sapiens 25-hydroxyvitamin D
           24-hydroxylase cytochrome P450 subunit protein.
          Length = 257

 Score = 80.6 bits (190), Expect = 9e-15
 Identities = 57/194 (29%), Positives = 96/194 (49%), Gaps = 10/194 (5%)

Query: 174 TETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYENI 233
           ++ EL A +    +A  ETT N+L+  ++ L+ +P +Q  L +E+++          E++
Sbjct: 55  SKKELYAAVTELQLAAVETTANSLMWILYNLSRNPQVQQKLLKEIQSVLPENQVPRAEDL 114

Query: 234 GELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHM 293
             + YL   L E+MR   +  F  R   K  VL      G+   L  G V+      +  
Sbjct: 115 RNMPYLKACLKESMRLTPSVPFTTRTLDKATVL------GEYA-LPKGTVLMLNTQVLGS 167

Query: 294 DPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNF 353
               +E+  +F PER+L E K KI PF  +PFGVG R CIG R A +++ + L  ++  +
Sbjct: 168 SEDNFEDSSQFRPERWLQE-KEKINPFAHLPFGVGKRMCIGRRLAELQLHLALCWIVRKY 226

Query: 354 KVLKCAKTLDPIKM 367
            +   A   +P++M
Sbjct: 227 DIQ--ATDNEPVEM 238


>AY858838-1|AAW50795.1|  372|Homo sapiens vitamin D 24-hydroxylase
           splice variant protein.
          Length = 372

 Score = 80.6 bits (190), Expect = 9e-15
 Identities = 57/194 (29%), Positives = 96/194 (49%), Gaps = 10/194 (5%)

Query: 174 TETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYENI 233
           ++ EL A +    +A  ETT N+L+  ++ L+ +P +Q  L +E+++          E++
Sbjct: 170 SKKELYAAVTELQLAAVETTANSLMWILYNLSRNPQVQQKLLKEIQSVLPENQVPRAEDL 229

Query: 234 GELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHM 293
             + YL   L E+MR   +  F  R   K  VL      G+   L  G V+      +  
Sbjct: 230 RNMPYLKACLKESMRLTPSVPFTTRTLDKATVL------GEYA-LPKGTVLMLNTQVLGS 282

Query: 294 DPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNF 353
               +E+  +F PER+L E K KI PF  +PFGVG R CIG R A +++ + L  ++  +
Sbjct: 283 SEDNFEDSSQFRPERWLQE-KEKINPFAHLPFGVGKRMCIGRRLAELQLHLALCWIVRKY 341

Query: 354 KVLKCAKTLDPIKM 367
            +   A   +P++M
Sbjct: 342 DIQ--ATDNEPVEM 353


>AL138805-3|CAB91829.1|  514|Homo sapiens cytochrome P450, family
           24, subfamily A, polypeptide 1 protein.
          Length = 514

 Score = 80.6 bits (190), Expect = 9e-15
 Identities = 57/194 (29%), Positives = 96/194 (49%), Gaps = 10/194 (5%)

Query: 174 TETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYENI 233
           ++ EL A +    +A  ETT N+L+  ++ L+ +P +Q  L +E+++          E++
Sbjct: 312 SKKELYAAVTELQLAAVETTANSLMWILYNLSRNPQVQQKLLKEIQSVLPENQVPRAEDL 371

Query: 234 GELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHM 293
             + YL   L E+MR   +  F  R   K  VL      G+   L  G V+      +  
Sbjct: 372 RNMPYLKACLKESMRLTPSVPFTTRTLDKATVL------GEYA-LPKGTVLMLNTQVLGS 424

Query: 294 DPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNF 353
               +E+  +F PER+L E K KI PF  +PFGVG R CIG R A +++ + L  ++  +
Sbjct: 425 SEDNFEDSSQFRPERWLQE-KEKINPFAHLPFGVGKRMCIGRRLAELQLHLALCWIVRKY 483

Query: 354 KVLKCAKTLDPIKM 367
            +   A   +P++M
Sbjct: 484 DIQ--ATDNEPVEM 495


>AL138805-1|CAM27342.1|  372|Homo sapiens cytochrome P450, family
           24, subfamily A, polypeptide 1 protein.
          Length = 372

 Score = 80.6 bits (190), Expect = 9e-15
 Identities = 57/194 (29%), Positives = 96/194 (49%), Gaps = 10/194 (5%)

Query: 174 TETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYENI 233
           ++ EL A +    +A  ETT N+L+  ++ L+ +P +Q  L +E+++          E++
Sbjct: 170 SKKELYAAVTELQLAAVETTANSLMWILYNLSRNPQVQQKLLKEIQSVLPENQVPRAEDL 229

Query: 234 GELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHM 293
             + YL   L E+MR   +  F  R   K  VL      G+   L  G V+      +  
Sbjct: 230 RNMPYLKACLKESMRLTPSVPFTTRTLDKATVL------GEYA-LPKGTVLMLNTQVLGS 282

Query: 294 DPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNF 353
               +E+  +F PER+L E K KI PF  +PFGVG R CIG R A +++ + L  ++  +
Sbjct: 283 SEDNFEDSSQFRPERWLQE-KEKINPFAHLPFGVGKRMCIGRRLAELQLHLALCWIVRKY 341

Query: 354 KVLKCAKTLDPIKM 367
            +   A   +P++M
Sbjct: 342 DIQ--ATDNEPVEM 353


>BC093896-1|AAH93896.1|  531|Homo sapiens cytochrome P450, family 2,
           subfamily E, polypeptide 2 homolog protein.
          Length = 531

 Score = 80.2 bits (189), Expect = 1e-14
 Identities = 44/186 (23%), Positives = 92/186 (49%), Gaps = 8/186 (4%)

Query: 172 EWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKG--NLV 229
           E ++ ++ A+   F   G +TT + +   +  LA  P  Q+   EE++   + +    L 
Sbjct: 319 ELSDEDIRAEADTFMFEGHDTTSSGISWMLFNLAKYPEYQEKCREEIQEVMKGRELEELE 378

Query: 230 YENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVN 289
           ++++ +L +    + E++R++     V R CT+   LP  R       +  G +   ++ 
Sbjct: 379 WDDLTQLPFTTMCIKESLRQYPPVTLVSRQCTEDIKLPDGRI------IPKGIICLVSIY 432

Query: 290 SIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRL 349
             H +P  + + + + P RF  +N  +  P  ++PF  GPR CIG  FA+ E+++++   
Sbjct: 433 GTHHNPTVWPDSKVYNPYRFDPDNPQQRSPLAYVPFSAGPRNCIGQSFAMAELRVVVALT 492

Query: 350 MLNFKV 355
           +L F++
Sbjct: 493 LLRFRL 498


>BC093894-1|AAH93894.1|  531|Homo sapiens cytochrome P450, family 2,
           subfamily E, polypeptide 2 homolog protein.
          Length = 531

 Score = 80.2 bits (189), Expect = 1e-14
 Identities = 44/186 (23%), Positives = 92/186 (49%), Gaps = 8/186 (4%)

Query: 172 EWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKG--NLV 229
           E ++ ++ A+   F   G +TT + +   +  LA  P  Q+   EE++   + +    L 
Sbjct: 319 ELSDEDIRAEADTFMFEGHDTTSSGISWMLFNLAKYPEYQEKCREEIQEVMKGRELEELE 378

Query: 230 YENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVN 289
           ++++ +L +    + E++R++     V R CT+   LP  R       +  G +   ++ 
Sbjct: 379 WDDLTQLPFTTMCIKESLRQYPPVTLVSRQCTEDIKLPDGRI------IPKGIICLVSIY 432

Query: 290 SIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRL 349
             H +P  + + + + P RF  +N  +  P  ++PF  GPR CIG  FA+ E+++++   
Sbjct: 433 GTHHNPTVWPDSKVYNPYRFDPDNPQQRSPLAYVPFSAGPRNCIGQSFAMAELRVVVALT 492

Query: 350 MLNFKV 355
           +L F++
Sbjct: 493 LLRFRL 498


>BC069351-1|AAH69351.1|  531|Homo sapiens cytochrome P450, family 2,
           subfamily E, polypeptide 2 homolog protein.
          Length = 531

 Score = 80.2 bits (189), Expect = 1e-14
 Identities = 44/186 (23%), Positives = 92/186 (49%), Gaps = 8/186 (4%)

Query: 172 EWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKG--NLV 229
           E ++ ++ A+   F   G +TT + +   +  LA  P  Q+   EE++   + +    L 
Sbjct: 319 ELSDEDIRAEADTFMFEGHDTTSSGISWMLFNLAKYPEYQEKCREEIQEVMKGRELEELE 378

Query: 230 YENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVN 289
           ++++ +L +    + E++R++     V R CT+   LP  R       +  G +   ++ 
Sbjct: 379 WDDLTQLPFTTMCIKESLRQYPPVTLVSRQCTEDIKLPDGRI------IPKGIICLVSIY 432

Query: 290 SIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRL 349
             H +P  + + + + P RF  +N  +  P  ++PF  GPR CIG  FA+ E+++++   
Sbjct: 433 GTHHNPTVWPDSKVYNPYRFDPDNPQQRSPLAYVPFSAGPRNCIGQSFAMAELRVVVALT 492

Query: 350 MLNFKV 355
           +L F++
Sbjct: 493 LLRFRL 498


>AK096820-1|BAC04868.1|  531|Homo sapiens protein ( Homo sapiens
           cDNA FLJ39501 fis, clone PROST2016980, moderately
           similar to CYTOCHROME P450 4F2 (EC 1.14.13.30). ).
          Length = 531

 Score = 80.2 bits (189), Expect = 1e-14
 Identities = 44/186 (23%), Positives = 92/186 (49%), Gaps = 8/186 (4%)

Query: 172 EWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKG--NLV 229
           E ++ ++ A+   F   G +TT + +   +  LA  P  Q+   EE++   + +    L 
Sbjct: 319 ELSDEDIRAEADTFMFEGHDTTSSGISWMLFNLAKYPEYQEKCREEIQEVMKGRELEELE 378

Query: 230 YENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVN 289
           ++++ +L +    + E++R++     V R CT+   LP  R       +  G +   ++ 
Sbjct: 379 WDDLTQLPFTTMCIKESLRQYPPVTLVSRQCTEDIKLPDGRI------IPKGIICLVSIY 432

Query: 290 SIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRL 349
             H +P  + + + + P RF  +N  +  P  ++PF  GPR CIG  FA+ E+++++   
Sbjct: 433 GTHHNPTVWPDSKVYNPYRFDPDNPQQRSPLAYVPFSAGPRNCIGQSFAMAELRVVVALT 492

Query: 350 MLNFKV 355
           +L F++
Sbjct: 493 LLRFRL 498


>BC104909-1|AAI04910.1|  501|Homo sapiens cytochrome P450, family 2,
           subfamily R, polypeptide 1 protein.
          Length = 501

 Score = 79.4 bits (187), Expect = 2e-14
 Identities = 50/184 (27%), Positives = 87/184 (47%), Gaps = 6/184 (3%)

Query: 170 STEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLV 229
           S+ +++  L   +    +AG ETT N L   I  +AL P+IQ  + +E+       G   
Sbjct: 292 SSTFSKENLIFSVGELIIAGTETTTNVLRWAILFMALYPNIQGQVQKEIDLIMGPNGKPS 351

Query: 230 YENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVN 289
           +++  ++ Y + VL+E +R      F + +    +         +   +  G  +   + 
Sbjct: 352 WDDKCKMPYTEAVLHEVLR------FCNIVPLGIFHATSEDAVVRGYSIPKGTTVITNLY 405

Query: 290 SIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRL 349
           S+H D  Y+ +PE F PERFLD + +  K    +PF +G R+C+G   A MEM +    L
Sbjct: 406 SVHFDEKYWRDPEVFHPERFLDSSGYFAKKEALVPFSLGRRHCLGEHLARMEMFLFFTAL 465

Query: 350 MLNF 353
           +  F
Sbjct: 466 LQRF 469


>BC104907-1|AAI04908.1|  501|Homo sapiens cytochrome P450, family 2,
           subfamily R, polypeptide 1 protein.
          Length = 501

 Score = 79.4 bits (187), Expect = 2e-14
 Identities = 50/184 (27%), Positives = 87/184 (47%), Gaps = 6/184 (3%)

Query: 170 STEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLV 229
           S+ +++  L   +    +AG ETT N L   I  +AL P+IQ  + +E+       G   
Sbjct: 292 SSTFSKENLIFSVGELIIAGTETTTNVLRWAILFMALYPNIQGQVQKEIDLIMGPNGKPS 351

Query: 230 YENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVN 289
           +++  ++ Y + VL+E +R      F + +    +         +   +  G  +   + 
Sbjct: 352 WDDKCKMPYTEAVLHEVLR------FCNIVPLGIFHATSEDAVVRGYSIPKGTTVITNLY 405

Query: 290 SIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRL 349
           S+H D  Y+ +PE F PERFLD + +  K    +PF +G R+C+G   A MEM +    L
Sbjct: 406 SVHFDEKYWRDPEVFHPERFLDSSGYFAKKEALVPFSLGRRHCLGEHLARMEMFLFFTAL 465

Query: 350 MLNF 353
           +  F
Sbjct: 466 LQRF 469


>AY323817-1|AAQ23114.1|  501|Homo sapiens cytochrome P450 2R1
           protein.
          Length = 501

 Score = 79.4 bits (187), Expect = 2e-14
 Identities = 50/184 (27%), Positives = 87/184 (47%), Gaps = 6/184 (3%)

Query: 170 STEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLV 229
           S+ +++  L   +    +AG ETT N L   I  +AL P+IQ  + +E+       G   
Sbjct: 292 SSTFSKENLIFSVGELIIAGTETTTNVLRWAILFMALYPNIQGQVQKEIDLIMGPNGKPS 351

Query: 230 YENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVN 289
           +++  ++ Y + VL+E +R      F + +    +         +   +  G  +   + 
Sbjct: 352 WDDKCKMPYTEAVLHEVLR------FCNIVPLGIFHATSEDAVVRGYSIPKGTTVITNLY 405

Query: 290 SIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRL 349
           S+H D  Y+ +PE F PERFLD + +  K    +PF +G R+C+G   A MEM +    L
Sbjct: 406 SVHFDEKYWRDPEVFHPERFLDSSGYFAKKEALVPFSLGRRHCLGEHLARMEMFLFFTAL 465

Query: 350 MLNF 353
           +  F
Sbjct: 466 LQRF 469


>X59812-1|CAA42481.1|  530|Homo sapiens Vitamin D3 25-hydroxylase
           protein.
          Length = 530

 Score = 77.4 bits (182), Expect = 8e-14
 Identities = 59/196 (30%), Positives = 93/196 (47%), Gaps = 11/196 (5%)

Query: 170 STEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLV 229
           S + +  E    L    +AG +TT NTL   ++ L+  P IQ+ L+EE+           
Sbjct: 316 SGQLSPREAMGSLPELLMAGVDTTSNTLTWALYHLSKDPEIQEALHEEVVGVVPAGQVPQ 375

Query: 230 YENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVN 289
           +++   +  L  VL ET+R +       RI  K   +      G         V  + V 
Sbjct: 376 HKDFAHMPLLKAVLKETLRLYPVVPTNSRIIEKEIEVD-----GFLFPKNTQFVFCHYV- 429

Query: 290 SIHMDPIYYEEPEKFIPERFLDENKH---KIK-PFTFMPFGVGPRYCIGSRFALMEMKIL 345
            +  DP  + EPE F P R+L  ++    +I+ PF  +PFG G R C+G R A +EM++L
Sbjct: 430 -VSRDPTAFSEPESFQPHRWLRNSQPATPRIQHPFGSVPFGYGVRACLGRRIAELEMQLL 488

Query: 346 LFRLMLNFKVLKCAKT 361
           L RL+  +KV+   +T
Sbjct: 489 LARLIQKYKVVLAPET 504


>M62401-1|AAA52142.1|  531|Homo sapiens sterol 27-hydroxylase
           protein.
          Length = 531

 Score = 77.4 bits (182), Expect = 8e-14
 Identities = 59/196 (30%), Positives = 93/196 (47%), Gaps = 11/196 (5%)

Query: 170 STEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLV 229
           S + +  E    L    +AG +TT NTL   ++ L+  P IQ+ L+EE+           
Sbjct: 317 SGQLSPREAMGSLPELLMAGVDTTSNTLTWALYHLSKDPEIQEALHEEVVGVVPAGQVPQ 376

Query: 230 YENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVN 289
           +++   +  L  VL ET+R +       RI  K   +      G         V  + V 
Sbjct: 377 HKDFAHMPLLKAVLKETLRLYPVVPTNSRIIEKEIEVD-----GFLFPKNTQFVFCHYV- 430

Query: 290 SIHMDPIYYEEPEKFIPERFLDENKH---KIK-PFTFMPFGVGPRYCIGSRFALMEMKIL 345
            +  DP  + EPE F P R+L  ++    +I+ PF  +PFG G R C+G R A +EM++L
Sbjct: 431 -VSRDPTAFSEPESFQPHRWLRNSQPATPRIQHPFGSVPFGYGVRACLGRRIAELEMQLL 489

Query: 346 LFRLMLNFKVLKCAKT 361
           L RL+  +KV+   +T
Sbjct: 490 LARLIQKYKVVLAPET 505


>BC051851-1|AAH51851.1|  531|Homo sapiens cytochrome P450, family
           27, subfamily A, polypeptide 1 protein.
          Length = 531

 Score = 77.4 bits (182), Expect = 8e-14
 Identities = 59/196 (30%), Positives = 93/196 (47%), Gaps = 11/196 (5%)

Query: 170 STEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLV 229
           S + +  E    L    +AG +TT NTL   ++ L+  P IQ+ L+EE+           
Sbjct: 317 SGQLSPREAMGSLPELLMAGVDTTSNTLTWALYHLSKDPEIQEALHEEVVGVVPAGQVPQ 376

Query: 230 YENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVN 289
           +++   +  L  VL ET+R +       RI  K   +      G         V  + V 
Sbjct: 377 HKDFAHMPLLKAVLKETLRLYPVVPTNSRIIEKEIEVD-----GFLFPKNTQFVFCHYV- 430

Query: 290 SIHMDPIYYEEPEKFIPERFLDENKH---KIK-PFTFMPFGVGPRYCIGSRFALMEMKIL 345
            +  DP  + EPE F P R+L  ++    +I+ PF  +PFG G R C+G R A +EM++L
Sbjct: 431 -VSRDPTAFSEPESFQPHRWLRNSQPATPRIQHPFGSVPFGYGVRACLGRRIAELEMQLL 489

Query: 346 LFRLMLNFKVLKCAKT 361
           L RL+  +KV+   +T
Sbjct: 490 LARLIQKYKVVLAPET 505


>BC040430-1|AAH40430.1|  531|Homo sapiens cytochrome P450, family
           27, subfamily A, polypeptide 1 protein.
          Length = 531

 Score = 77.4 bits (182), Expect = 8e-14
 Identities = 59/196 (30%), Positives = 93/196 (47%), Gaps = 11/196 (5%)

Query: 170 STEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLV 229
           S + +  E    L    +AG +TT NTL   ++ L+  P IQ+ L+EE+           
Sbjct: 317 SGQLSPREAMGSLPELLMAGVDTTSNTLTWALYHLSKDPEIQEALHEEVVGVVPAGQVPQ 376

Query: 230 YENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVN 289
           +++   +  L  VL ET+R +       RI  K   +      G         V  + V 
Sbjct: 377 HKDFAHMPLLKAVLKETLRLYPVVPTNSRIIEKEIEVD-----GFLFPKNTQFVFCHYV- 430

Query: 290 SIHMDPIYYEEPEKFIPERFLDENKH---KIK-PFTFMPFGVGPRYCIGSRFALMEMKIL 345
            +  DP  + EPE F P R+L  ++    +I+ PF  +PFG G R C+G R A +EM++L
Sbjct: 431 -VSRDPTAFSEPESFQPHRWLRNSQPATPRIQHPFGSVPFGYGVRACLGRRIAELEMQLL 489

Query: 346 LFRLMLNFKVLKCAKT 361
           L RL+  +KV+   +T
Sbjct: 490 LARLIQKYKVVLAPET 505


>BC117165-1|AAI17166.1|  494|Homo sapiens cytochrome P450, family 2,
           subfamily A, polypeptide 7 protein.
          Length = 494

 Score = 76.6 bits (180), Expect = 1e-13
 Identities = 56/205 (27%), Positives = 92/205 (44%), Gaps = 9/205 (4%)

Query: 170 STEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLV 229
           +TE+    L       F+AG ET   TL      L   P ++  ++EE+           
Sbjct: 283 NTEFYLKNLMMSTLNLFIAGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPK 342

Query: 230 YENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVN 289
           +E+  ++ Y++ V++E  R      F D I              +   L  G  ++  + 
Sbjct: 343 FEDRAKMPYMEAVIHEIQR------FGDVIPMSLARRVKKDTKFRDFFLPKGTEVFPMLG 396

Query: 290 SIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRL 349
           S+  DP ++  P+ F P+ FLD+     K   F+PF +G RYC G   A ME+ +    +
Sbjct: 397 SVLRDPSFFSNPQDFNPQHFLDDKGQFKKSDAFVPFSIGKRYCFGEGLARMELFLFFTTV 456

Query: 350 MLNFKVLKCAKTLDPIKMSP--VGF 372
           M NF+ LK +++   I +SP  VGF
Sbjct: 457 MQNFR-LKSSQSPKDIDVSPKHVGF 480


>AY178622-1|AAO21126.1|  531|Homo sapiens steroid hydroxylase
           protein.
          Length = 531

 Score = 76.2 bits (179), Expect = 2e-13
 Identities = 59/197 (29%), Positives = 94/197 (47%), Gaps = 13/197 (6%)

Query: 170 STEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLV 229
           S + +  E    L    +AG +TT NTL   ++ L+  P IQ  L+EE+           
Sbjct: 317 SGQLSPREAMGSLPELLMAGVDTTSNTLTWALYHLSKDPEIQKALHEEVVGVVPAGQVPQ 376

Query: 230 YENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVN 289
           +++   +  L  VL ET+R +       RI  K   +    +G     L P    +   +
Sbjct: 377 HKDFAHMPLLKAVLKETLRLYPVVPTNSRIIEKEIEV----DGF----LFPKNTQFVFCH 428

Query: 290 -SIHMDPIYYEEPEKFIPERFLDENKH---KIK-PFTFMPFGVGPRYCIGSRFALMEMKI 344
             +  DP  + EPE F P R+L  ++    +I+ PF  +PFG G R C+G R A +EM++
Sbjct: 429 YEVSRDPTAFSEPESFQPHRWLRNSQPATPRIQHPFGSVPFGYGVRACLGRRIAELEMQL 488

Query: 345 LLFRLMLNFKVLKCAKT 361
           LL RL+  +KV+   +T
Sbjct: 489 LLARLIQKYKVVLAPET 505


>AK090886-1|BAC03539.1|  337|Homo sapiens protein ( Homo sapiens
           cDNA FLJ33567 fis, clone BRAMY2010272, highly similar to
           Homo sapiens cholesterol 24-hydroxylase mRNA. ).
          Length = 337

 Score = 74.5 bits (175), Expect = 6e-13
 Identities = 57/175 (32%), Positives = 92/175 (52%), Gaps = 23/175 (13%)

Query: 185 FFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYENIGELKYLDCVLN 244
           FF+AG ET+ N L   + EL+  P I   L  E+     +K  L +E++G L+YL  VL 
Sbjct: 146 FFIAGHETSANHLAFTVMELSRQPEIVARLQAEVDEVIGSKRYLDFEDLGRLQYLSQVLK 205

Query: 245 ETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHMDPIYYEEPEKF 304
           E++R +  A    R+  +  ++    +G            ++T     MD  Y+E+P  F
Sbjct: 206 ESLRLYPPAWGTFRLLEEETLI----DG------------FSTYVMGRMDT-YFEDPLTF 248

Query: 305 IPERFLDENKHKIKP-FTFMPFGVGPRYCIGSRFALMEMKILLFRLM--LNFKVL 356
            P+RF        KP FT+ PF +G R CIG +FA ME+K+++ +L+  L F+++
Sbjct: 249 NPDRF---GPGAPKPRFTYFPFSLGHRSCIGQQFAQMEVKVVMAKLLQRLEFRLV 300


>S67581-1|AAB29503.1|  591|Homo sapiens fatty acid omega-hydroxylase
           protein.
          Length = 591

 Score = 74.1 bits (174), Expect = 8e-13
 Identities = 48/204 (23%), Positives = 95/204 (46%), Gaps = 9/204 (4%)

Query: 154 KNKVERRDMIQLL-MQLSTEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQD 212
           K  ++  D++ L  M+  +  ++ +L A++  F   G +TT + +   ++ LA  P  Q+
Sbjct: 286 KRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQE 345

Query: 213 ILYEELKAFKETKGNLVYENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREG 272
              EE+ +      ++ + ++ ++ Y    + E +R +     + R  + P   P  R  
Sbjct: 346 RCREEIHSLLGDGASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRS- 404

Query: 273 GKPCQLKPGEVIYNTVNSIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYC 332
                L  G ++  ++  +H +P  +  PE F P RF   +        F+PF  G R C
Sbjct: 405 -----LPKGIMVLLSIYGLHHNPKVWPNPEVFDPSRFAPGSAQH--SHAFLPFSGGSRNC 457

Query: 333 IGSRFALMEMKILLFRLMLNFKVL 356
           IG +FA+ E+K+     +L F++L
Sbjct: 458 IGKQFAMNELKVATALTLLRFELL 481


>S67580-1|AAB29502.1|  519|Homo sapiens fatty acid omega-hydroxylase
           protein.
          Length = 519

 Score = 74.1 bits (174), Expect = 8e-13
 Identities = 48/204 (23%), Positives = 95/204 (46%), Gaps = 9/204 (4%)

Query: 154 KNKVERRDMIQLL-MQLSTEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQD 212
           K  ++  D++ L  M+  +  ++ +L A++  F   G +TT + +   ++ LA  P  Q+
Sbjct: 286 KRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQE 345

Query: 213 ILYEELKAFKETKGNLVYENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREG 272
              EE+ +      ++ + ++ ++ Y    + E +R +     + R  + P   P  R  
Sbjct: 346 RCREEIHSLLGDGASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRS- 404

Query: 273 GKPCQLKPGEVIYNTVNSIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYC 332
                L  G ++  ++  +H +P  +  PE F P RF   +        F+PF  G R C
Sbjct: 405 -----LPKGIMVLLSIYGLHHNPKVWPNPEVFDPSRFAPGSAQH--SHAFLPFSGGSRNC 457

Query: 333 IGSRFALMEMKILLFRLMLNFKVL 356
           IG +FA+ E+K+     +L F++L
Sbjct: 458 IGKQFAMNELKVATALTLLRFELL 481


>DQ680079-1|ABG25922.1|  347|Homo sapiens truncated cytochrome P450,
           family 3, subfamily A, polypeptide 5 protein.
          Length = 347

 Score = 73.7 bits (173), Expect = 1e-12
 Identities = 40/118 (33%), Positives = 68/118 (57%), Gaps = 6/118 (5%)

Query: 2   NNLLRRTHLWEDYDVVYKAFPNERYVGFTDGVCPGIFIRDPEIIKHVTVKE-FDHFVNNK 60
           N L  R  LW+     YK +   +  G  +G  P + I DP++I+ V VKE +  F N +
Sbjct: 49  NVLSYRQGLWKFDTECYKKYG--KMWGTYEGQLPVLAITDPDVIRTVLVKECYSVFTNRR 106

Query: 61  DLSPEGEESILKNSLIMLKDEKWRKMRAALSPAFTASKMREMVPLITEISHNIVEYLK 118
            L P G    +K+++ + +DE+W+++R+ LSP FT+ K++EM P+I +    +V  L+
Sbjct: 107 SLGPVG---FMKSAISLAEDEEWKRIRSLLSPTFTSGKLKEMFPIIAQYGDVLVRNLR 161



 Score = 50.8 bits (116), Expect = 8e-06
 Identities = 38/117 (32%), Positives = 59/117 (50%), Gaps = 12/117 (10%)

Query: 121 FPSLS---KKLGFTIIPKSTSEFFRTLIASTVDYRIKNKVERR-DMIQLLM--QLSTEW- 173
           FP L+   + L  ++ PK T  F    +      R+ +K + R D +QL++  Q S E  
Sbjct: 226 FPFLTPVFEALNVSLFPKDTINFLSKSVNRMKKSRLNDKQKHRLDFLQLMIDSQNSKETE 285

Query: 174 -----TETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETK 225
                ++ ELAAQ  +F  AG+ETT + L   ++ELA  P +Q  L +E+ A    K
Sbjct: 286 SHKALSDLELAAQSIIFIFAGYETTSSVLSFTLYELATHPDVQQKLQKEIDAVLPNK 342


>AF280111-1|AAG33012.1|  250|Homo sapiens cytochrome P450 subfamily
           IIIA polypeptide 43 protein.
          Length = 250

 Score = 73.7 bits (173), Expect = 1e-12
 Identities = 41/100 (41%), Positives = 61/100 (61%), Gaps = 7/100 (7%)

Query: 23  NERYV---GFTDGVCPGIFIRDPEIIKHVTVKE-FDHFVNNKDLSPEGEESILKNSLIML 78
           NE+Y    G  +G  P + I DP++IK V VKE +  F N   L P G    LK++L   
Sbjct: 65  NEKYGEMWGLYEGQQPMLVIMDPDMIKTVLVKECYSVFTNQMPLGPMG---FLKSALSFA 121

Query: 79  KDEKWRKMRAALSPAFTASKMREMVPLITEISHNIVEYLK 118
           +DE+W+++R  LSPAFT+ K +EMVP+I++    +V  L+
Sbjct: 122 EDEEWKRIRTLLSPAFTSVKFKEMVPIISQCGDMLVRSLR 161


>L04751-1|AAA58436.1|  519|Homo sapiens cytochrome P450 protein.
          Length = 519

 Score = 72.9 bits (171), Expect = 2e-12
 Identities = 48/204 (23%), Positives = 95/204 (46%), Gaps = 9/204 (4%)

Query: 154 KNKVERRDMIQLL-MQLSTEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQD 212
           K  ++  D++ L  M+  +  ++ +L A++  F   G +TT + +   ++ LA  P  Q+
Sbjct: 286 KRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQE 345

Query: 213 ILYEELKAFKETKGNLVYENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREG 272
              EE+ +      ++ + ++ ++ Y    + E +R +     + R  + P   P  R  
Sbjct: 346 RCREEIHSLLGDGASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRS- 404

Query: 273 GKPCQLKPGEVIYNTVNSIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYC 332
                L  G ++  ++  +H +P  +  PE F P RF   +        F+PF  G R C
Sbjct: 405 -----LPKGIMVLLSIYGLHHNPKVWPNPEVFDPFRFAPGSAQH--SHAFLPFSGGSRNC 457

Query: 333 IGSRFALMEMKILLFRLMLNFKVL 356
           IG +FA+ E+K+     +L F++L
Sbjct: 458 IGKQFAMNELKVATALTLLRFELL 481


>D26481-1|BAA05491.1|  519|Homo sapiens fatty acids
           omega-hydroxylase protein.
          Length = 519

 Score = 72.9 bits (171), Expect = 2e-12
 Identities = 48/204 (23%), Positives = 95/204 (46%), Gaps = 9/204 (4%)

Query: 154 KNKVERRDMIQLL-MQLSTEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQD 212
           K  ++  D++ L  M+  +  ++ +L A++  F   G +TT + +   ++ LA  P  Q+
Sbjct: 286 KRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQE 345

Query: 213 ILYEELKAFKETKGNLVYENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREG 272
              EE+ +      ++ + ++ ++ Y    + E +R +     + R  + P   P  R  
Sbjct: 346 RCREEIHSLLGDGASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRS- 404

Query: 273 GKPCQLKPGEVIYNTVNSIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYC 332
                L  G ++  ++  +H +P  +  PE F P RF   +        F+PF  G R C
Sbjct: 405 -----LPKGIMVLLSIYGLHHNPKVWPNPEVFDPFRFAPGSAQH--SHAFLPFSGGSRNC 457

Query: 333 IGSRFALMEMKILLFRLMLNFKVL 356
           IG +FA+ E+K+     +L F++L
Sbjct: 458 IGKQFAMNELKVATALTLLRFELL 481


>AY369778-1|AAQ56847.1|  519|Homo sapiens cytochrome P450, family 4,
           subfamily A, polypeptide 11 protein.
          Length = 519

 Score = 72.9 bits (171), Expect = 2e-12
 Identities = 48/204 (23%), Positives = 95/204 (46%), Gaps = 9/204 (4%)

Query: 154 KNKVERRDMIQLL-MQLSTEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQD 212
           K  ++  D++ L  M+  +  ++ +L A++  F   G +TT + +   ++ LA  P  Q+
Sbjct: 286 KRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQE 345

Query: 213 ILYEELKAFKETKGNLVYENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREG 272
              EE+ +      ++ + ++ ++ Y    + E +R +     + R  + P   P  R  
Sbjct: 346 RCREEIHSLLGDGASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRS- 404

Query: 273 GKPCQLKPGEVIYNTVNSIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYC 332
                L  G ++  ++  +H +P  +  PE F P RF   +        F+PF  G R C
Sbjct: 405 -----LPKGIMVLLSIYGLHHNPKVWPNPEVFDPFRFAPGSAQH--SHAFLPFSGGSRNC 457

Query: 333 IGSRFALMEMKILLFRLMLNFKVL 356
           IG +FA+ E+K+     +L F++L
Sbjct: 458 IGKQFAMNELKVATALTLLRFELL 481


>AL731892-3|CAH72778.1|  519|Homo sapiens cytochrome P450, family 4,
           subfamily A, polypeptide 11 protein.
          Length = 519

 Score = 72.9 bits (171), Expect = 2e-12
 Identities = 48/204 (23%), Positives = 95/204 (46%), Gaps = 9/204 (4%)

Query: 154 KNKVERRDMIQLL-MQLSTEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQD 212
           K  ++  D++ L  M+  +  ++ +L A++  F   G +TT + +   ++ LA  P  Q+
Sbjct: 286 KRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQE 345

Query: 213 ILYEELKAFKETKGNLVYENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREG 272
              EE+ +      ++ + ++ ++ Y    + E +R +     + R  + P   P  R  
Sbjct: 346 RCREEIHSLLGDGASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRS- 404

Query: 273 GKPCQLKPGEVIYNTVNSIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYC 332
                L  G ++  ++  +H +P  +  PE F P RF   +        F+PF  G R C
Sbjct: 405 -----LPKGIMVLLSIYGLHHNPKVWPNPEVFDPFRFAPGSAQH--SHAFLPFSGGSRNC 457

Query: 333 IGSRFALMEMKILLFRLMLNFKVL 356
           IG +FA+ E+K+     +L F++L
Sbjct: 458 IGKQFAMNELKVATALTLLRFELL 481


>AF478474-1|AAL84813.1|  503|Homo sapiens mutated cytochrome
           P-450c11 protein protein.
          Length = 503

 Score = 72.9 bits (171), Expect = 2e-12
 Identities = 49/187 (26%), Positives = 89/187 (47%), Gaps = 8/187 (4%)

Query: 169 LSTEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNL 228
           L+ E +   + A          +TT   L+  + ELA +P++Q  L +E  A   +    
Sbjct: 295 LNAELSPDAIKANSMELTAGSMDTTVFPLLMTLFELARNPNVQQALRQESLAAAASISEH 354

Query: 229 VYENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTV 288
             +   EL  L   L ET+R +   +F++R+ +   VL       +   +  G ++   +
Sbjct: 355 PQKATTELPLLRAALKETLRLYPVGLFLERVASSDLVL-------QNYHIPAGTLVRVFL 407

Query: 289 NSIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFR 348
            S+  +P  +  PE++ P+R+LD  +   + F  +PFG G R C+G R A  EM +LL  
Sbjct: 408 YSLGRNPALFPRPERYNPQRWLDI-RGSGRNFYHVPFGFGMRQCLGRRLAEAEMLLLLHH 466

Query: 349 LMLNFKV 355
           ++ + +V
Sbjct: 467 VLKHLQV 473


>M33317-1|AAA52138.1|  494|Homo sapiens CYP2A protein.
          Length = 494

 Score = 72.5 bits (170), Expect = 2e-12
 Identities = 55/205 (26%), Positives = 91/205 (44%), Gaps = 9/205 (4%)

Query: 170 STEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLV 229
           +TE+    L       F+AG ET   TL      L   P ++  ++EE+           
Sbjct: 283 NTEFYLKNLMMSTLNLFIAGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPK 342

Query: 230 YENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVN 289
           +E+  ++ Y++ V++E  R      F D I              +   L  G  ++  + 
Sbjct: 343 FEDRTKMPYMEAVIHEIQR------FGDVIPMSLARRVKKDTKFRDFFLPKGTEVFPMLG 396

Query: 290 SIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRL 349
           S+  DP ++  P+ F P+ FLD+     K   F+PF +G RYC G   A ME+ +    +
Sbjct: 397 SVLRDPSFFSNPQDFNPQHFLDDKGQFKKSDAFVPFSIGKRYCFGEGLARMELFLFFTTV 456

Query: 350 MLNFKVLKCAKTLDPIKMSP--VGF 372
           M NF+ LK +++   I +S   VGF
Sbjct: 457 MQNFR-LKSSQSPKDIDVSSKHVGF 480


>M32879-1|AAA52149.1|  503|Homo sapiens CYP11B1 protein.
          Length = 503

 Score = 72.5 bits (170), Expect = 2e-12
 Identities = 49/187 (26%), Positives = 89/187 (47%), Gaps = 8/187 (4%)

Query: 169 LSTEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNL 228
           L+ E +   + A          +TT   L+  + ELA +P++Q  L +E  A   +    
Sbjct: 295 LNAELSPDAIKANSMELTAGSVDTTVFPLLMTLFELARNPNVQQALRQESLAAAASISEH 354

Query: 229 VYENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTV 288
             +   EL  L   L ET+R +   +F++R+ +   VL       +   +  G ++   +
Sbjct: 355 PQKATTELPLLRAALKETLRLYPVGLFLERVASSDLVL-------QNYHIPAGTLVRVFL 407

Query: 289 NSIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFR 348
            S+  +P  +  PE++ P+R+LD  +   + F  +PFG G R C+G R A  EM +LL  
Sbjct: 408 YSLGRNPALFPRPERYNPQRWLDI-RGSGRNFYHVPFGFGMRQCLGRRLAEAEMLLLLHH 466

Query: 349 LMLNFKV 355
           ++ + +V
Sbjct: 467 VLKHLQV 473


>BC096287-1|AAH96287.1|  503|Homo sapiens cytochrome P450, family
           11, subfamily B, polypeptide 1 protein.
          Length = 503

 Score = 72.5 bits (170), Expect = 2e-12
 Identities = 49/187 (26%), Positives = 89/187 (47%), Gaps = 8/187 (4%)

Query: 169 LSTEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNL 228
           L+ E +   + A          +TT   L+  + ELA +P++Q  L +E  A   +    
Sbjct: 295 LNAELSPDAIKANSMELTAGSVDTTVFPLLMTLFELARNPNVQQALRQESLAAAASISEH 354

Query: 229 VYENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTV 288
             +   EL  L   L ET+R +   +F++R+ +   VL       +   +  G ++   +
Sbjct: 355 PQKATTELPLLRAALKETLRLYPVGLFLERVASSDLVL-------QNYHIPAGTLVRVFL 407

Query: 289 NSIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFR 348
            S+  +P  +  PE++ P+R+LD  +   + F  +PFG G R C+G R A  EM +LL  
Sbjct: 408 YSLGRNPALFPRPERYNPQRWLDI-RGSGRNFYHVPFGFGMRQCLGRRLAEAEMLLLLHH 466

Query: 349 LMLNFKV 355
           ++ + +V
Sbjct: 467 VLKHLQV 473


>BC096285-1|AAH96285.1|  574|Homo sapiens CYP11B1 protein protein.
          Length = 574

 Score = 72.5 bits (170), Expect = 2e-12
 Identities = 49/187 (26%), Positives = 89/187 (47%), Gaps = 8/187 (4%)

Query: 169 LSTEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNL 228
           L+ E +   + A          +TT   L+  + ELA +P++Q  L +E  A   +    
Sbjct: 366 LNAELSPDAIKANSMELTAGSVDTTVFPLLMTLFELARNPNVQQALRQESLAAAASISEH 425

Query: 229 VYENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTV 288
             +   EL  L   L ET+R +   +F++R+ +   VL       +   +  G ++   +
Sbjct: 426 PQKATTELPLLRAALKETLRLYPVGLFLERVASSDLVL-------QNYHIPAGTLVRVFL 478

Query: 289 NSIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFR 348
            S+  +P  +  PE++ P+R+LD  +   + F  +PFG G R C+G R A  EM +LL  
Sbjct: 479 YSLGRNPALFPRPERYNPQRWLDI-RGSGRNFYHVPFGFGMRQCLGRRLAEAEMLLLLHH 537

Query: 349 LMLNFKV 355
           ++ + +V
Sbjct: 538 VLKHLQV 544


>AY280372-1|AAQ21368.1|  519|Homo sapiens cytochrome P450 4A22
           protein.
          Length = 519

 Score = 72.5 bits (170), Expect = 2e-12
 Identities = 51/216 (23%), Positives = 99/216 (45%), Gaps = 10/216 (4%)

Query: 154 KNKVERRDMIQLL-MQLSTEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQD 212
           K  ++  D++ L  M+  +  ++ +L A++  F   G +TT + +   ++ LA  P  Q+
Sbjct: 286 KRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQE 345

Query: 213 ILYEELKAFKETKGNLVYENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREG 272
              EE+        ++ + ++ ++ Y    + E +R +     + R  + P   P  R  
Sbjct: 346 RCREEIHGLLGDGASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGR-- 403

Query: 273 GKPCQLKPGEVIYNTVNSIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYC 332
                L  G ++  ++  +H +P  +  PE F P RF   +        F+PF  G R C
Sbjct: 404 ----SLPKGIMVLLSIYGLHHNPKVWPNPEVFDPSRFAPGSAQ--HSHAFLPFSGGSRNC 457

Query: 333 IGSRFALMEMKILLFRLMLNFKVLKCAKTLDPIKMS 368
           IG +FA+ ++K+     +L F++L    T  PI M+
Sbjct: 458 IGKQFAMNQLKVARALTLLRFELLP-DPTRIPIPMA 492


>AY280371-1|AAQ21367.1|  519|Homo sapiens cytochrome P450 4A22K
           protein.
          Length = 519

 Score = 72.5 bits (170), Expect = 2e-12
 Identities = 51/216 (23%), Positives = 100/216 (46%), Gaps = 10/216 (4%)

Query: 154 KNKVERRDMIQLL-MQLSTEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQD 212
           K  ++  D++ L  M+  +  ++ +L A++  F   G +TT + +   ++ LA  P  Q+
Sbjct: 286 KRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQE 345

Query: 213 ILYEELKAFKETKGNLVYENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREG 272
              EE+ +      ++ + ++ ++ Y    + E +R +     + R  + P   P  R  
Sbjct: 346 RCREEIHSLLGDGASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGR-- 403

Query: 273 GKPCQLKPGEVIYNTVNSIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYC 332
                L  G ++  ++  +H +P  +  PE F P RF   +        F+PF  G R C
Sbjct: 404 ----SLPKGIMVLLSIYGLHHNPKVWPNPEVFDPFRFAPGSAQ--HSHAFLPFSGGSRNC 457

Query: 333 IGSRFALMEMKILLFRLMLNFKVLKCAKTLDPIKMS 368
           IG +FA+ ++K+     +L F++L    T  PI M+
Sbjct: 458 IGKQFAMNQLKVARALTLLRFELLP-DPTRTPIPMA 492


>AF525488-1|AAO16078.1|  519|Homo sapiens cytochrome P450, subfamily
           IVA, polypeptide 11 protein.
          Length = 519

 Score = 72.5 bits (170), Expect = 2e-12
 Identities = 48/204 (23%), Positives = 95/204 (46%), Gaps = 9/204 (4%)

Query: 154 KNKVERRDMIQLL-MQLSTEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQD 212
           K  ++  D++ L  M+  +  ++ +L A++  F   G +TT + +   ++ LA  P  Q+
Sbjct: 286 KRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQE 345

Query: 213 ILYEELKAFKETKGNLVYENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREG 272
              EE+ +      ++ + ++ ++ Y    + E +R +     + R  + P   P  R  
Sbjct: 346 RCREEIHSLLGDGASITWNHLDQMPYTTMCIKEALRLFPPVPGIGRELSTPVTFPDGRS- 404

Query: 273 GKPCQLKPGEVIYNTVNSIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYC 332
                L  G ++  ++  +H +P  +  PE F P RF   +        F+PF  G R C
Sbjct: 405 -----LPKGIMVLLSIYGLHHNPKVWPNPEVFDPFRFAPGSAQH--SHAFLPFSGGSRNC 457

Query: 333 IGSRFALMEMKILLFRLMLNFKVL 356
           IG +FA+ E+K+     +L F++L
Sbjct: 458 IGKQFAMNELKVATALTLLRFELL 481


>X55764-1|CAA39290.1|  503|Homo sapiens protein ( Human mRNA for
           cytochrome P-450 (11 Beta). ).
          Length = 503

 Score = 72.1 bits (169), Expect = 3e-12
 Identities = 49/187 (26%), Positives = 89/187 (47%), Gaps = 8/187 (4%)

Query: 169 LSTEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNL 228
           L+ E +   + A          +TT   L+  + ELA +P++Q  L +E  A   +    
Sbjct: 295 LNAELSPDAIKANSMELTAGSVDTTVFPLLMTLFELARNPNVQQALRQESLAAAASISEH 354

Query: 229 VYENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTV 288
             +   EL  L   L ET+R +   +F++R+ +   VL       +   +  G ++   +
Sbjct: 355 PQKATTELPLLRAALKETLRLYPVGLFLERVVSSDLVL-------QNYHIPAGTLVRVFL 407

Query: 289 NSIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFR 348
            S+  +P  +  PE++ P+R+LD  +   + F  +PFG G R C+G R A  EM +LL  
Sbjct: 408 YSLGRNPALFPRPERYNPQRWLDI-RGSGRNFYHVPFGFGMRQCLGRRLAEAEMLLLLHH 466

Query: 349 LMLNFKV 355
           ++ + +V
Sbjct: 467 VLKHLQV 473


>X13930-1|CAA32118.1|  494|Homo sapiens protein ( Human CYP2A4 mRNA
           for P-450 IIA4 protein. ).
          Length = 494

 Score = 72.1 bits (169), Expect = 3e-12
 Identities = 55/205 (26%), Positives = 90/205 (43%), Gaps = 9/205 (4%)

Query: 170 STEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLV 229
           +TE+    L       F+ G ET   TL      L   P ++  ++EE+           
Sbjct: 283 NTEFYLKNLVMTTLNLFIGGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPK 342

Query: 230 YENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVN 289
           +E+  ++ Y++ V++E  R      F D I              +   L  G  +Y  + 
Sbjct: 343 FEDRAKMPYMEAVIHEIQR------FGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLG 396

Query: 290 SIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRL 349
           S+  DP ++  P+ F P+ FL+E     K   F+PF +G R C G   A ME+ +    +
Sbjct: 397 SVLRDPSFFSNPQDFNPQHFLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTV 456

Query: 350 MLNFKVLKCAKTLDPIKMSP--VGF 372
           M NF+ LK +++   I +SP  VGF
Sbjct: 457 MQNFR-LKSSQSPKDIDVSPKHVGF 480


>X13929-1|CAA32117.1|  448|Homo sapiens P-450 IIA3 protein (1 is 3rd
           base in codon) protein.
          Length = 448

 Score = 72.1 bits (169), Expect = 3e-12
 Identities = 55/205 (26%), Positives = 90/205 (43%), Gaps = 9/205 (4%)

Query: 170 STEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLV 229
           +TE+    L       F+ G ET   TL      L   P ++  ++EE+           
Sbjct: 237 NTEFYLKNLVMTTLNLFIGGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPK 296

Query: 230 YENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVN 289
           +E+  ++ Y++ V++E  R      F D I              +   L  G  +Y  + 
Sbjct: 297 FEDRAKMPYMEAVIHEIQR------FGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLG 350

Query: 290 SIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRL 349
           S+  DP ++  P+ F P+ FL+E     K   F+PF +G R C G   A ME+ +    +
Sbjct: 351 SVLRDPSFFSNPQDFNPQHFLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTV 410

Query: 350 MLNFKVLKCAKTLDPIKMSP--VGF 372
           M NF+ LK +++   I +SP  VGF
Sbjct: 411 MQNFR-LKSSQSPKDIDVSPKHVGF 434


>X13897-1|CAA32097.1|  489|Homo sapiens protein ( Human mRNA for
           cytochrome P-450IIA. ).
          Length = 489

 Score = 72.1 bits (169), Expect = 3e-12
 Identities = 55/205 (26%), Positives = 90/205 (43%), Gaps = 9/205 (4%)

Query: 170 STEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLV 229
           +TE+    L       F+ G ET   TL      L   P ++  ++EE+           
Sbjct: 278 NTEFYLKNLVMTTLNLFIGGTETVSTTLRYGFLLLMKHPEVEAQVHEEIDRVIGKNRQPK 337

Query: 230 YENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVN 289
           +E+  ++ Y++ V++E  R      F D I              +   L  G  +Y  + 
Sbjct: 338 FEDRAKMPYMEAVIHEIQR------FGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLG 391

Query: 290 SIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRL 349
           S+  DP ++  P+ F P+ FL+E     K   F+PF +G R C G   A ME+ +    +
Sbjct: 392 SVLRDPSFFSNPQDFNPQHFLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTV 451

Query: 350 MLNFKVLKCAKTLDPIKMSP--VGF 372
           M NF+ LK +++   I +SP  VGF
Sbjct: 452 MQNFR-LKSSQSPKDIDVSPKHVGF 475


>M33318-1|AAA52067.1|  494|Homo sapiens CYP2A protein.
          Length = 494

 Score = 72.1 bits (169), Expect = 3e-12
 Identities = 55/205 (26%), Positives = 90/205 (43%), Gaps = 9/205 (4%)

Query: 170 STEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLV 229
           +TE+    L       F+ G ET   TL      L   P ++  ++EE+           
Sbjct: 283 NTEFYLKNLVMTTLNLFIGGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPK 342

Query: 230 YENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVN 289
           +E+  ++ Y++ V++E  R      F D I              +   L  G  +Y  + 
Sbjct: 343 FEDRAKMPYMEAVIHEIQR------FGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLG 396

Query: 290 SIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRL 349
           S+  DP ++  P+ F P+ FL+E     K   F+PF +G R C G   A ME+ +    +
Sbjct: 397 SVLRDPSFFSNPQDFNPQHFLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTV 456

Query: 350 MLNFKVLKCAKTLDPIKMSP--VGF 372
           M NF+ LK +++   I +SP  VGF
Sbjct: 457 MQNFR-LKSSQSPKDIDVSPKHVGF 480


>BC096256-1|AAH96256.1|  494|Homo sapiens cytochrome P450, family 2,
           subfamily A, polypeptide 6 protein.
          Length = 494

 Score = 72.1 bits (169), Expect = 3e-12
 Identities = 55/205 (26%), Positives = 90/205 (43%), Gaps = 9/205 (4%)

Query: 170 STEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLV 229
           +TE+    L       F+ G ET   TL      L   P ++  ++EE+           
Sbjct: 283 NTEFYLKNLVMTTLNLFIGGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPK 342

Query: 230 YENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVN 289
           +E+  ++ Y++ V++E  R      F D I              +   L  G  +Y  + 
Sbjct: 343 FEDRAKMPYMEAVIHEIQR------FGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLG 396

Query: 290 SIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRL 349
           S+  DP ++  P+ F P+ FL+E     K   F+PF +G R C G   A ME+ +    +
Sbjct: 397 SVLRDPSFFSNPQDFNPQHFLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTV 456

Query: 350 MLNFKVLKCAKTLDPIKMSP--VGF 372
           M NF+ LK +++   I +SP  VGF
Sbjct: 457 MQNFR-LKSSQSPKDIDVSPRHVGF 480


>BC096255-1|AAH96255.1|  494|Homo sapiens cytochrome P450, family 2,
           subfamily A, polypeptide 6 protein.
          Length = 494

 Score = 72.1 bits (169), Expect = 3e-12
 Identities = 55/205 (26%), Positives = 90/205 (43%), Gaps = 9/205 (4%)

Query: 170 STEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLV 229
           +TE+    L       F+ G ET   TL      L   P ++  ++EE+           
Sbjct: 283 NTEFYLKNLVMTTLNLFIGGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPK 342

Query: 230 YENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVN 289
           +E+  ++ Y++ V++E  R      F D I              +   L  G  +Y  + 
Sbjct: 343 FEDRAKMPYMEAVIHEIQR------FGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLG 396

Query: 290 SIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRL 349
           S+  DP ++  P+ F P+ FL+E     K   F+PF +G R C G   A ME+ +    +
Sbjct: 397 SVLRDPSFFSNPQDFNPQHFLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTV 456

Query: 350 MLNFKVLKCAKTLDPIKMSP--VGF 372
           M NF+ LK +++   I +SP  VGF
Sbjct: 457 MQNFR-LKSSQSPKDIDVSPKHVGF 480


>BC096254-1|AAH96254.1|  494|Homo sapiens cytochrome P450, family 2,
           subfamily A, polypeptide 6 protein.
          Length = 494

 Score = 72.1 bits (169), Expect = 3e-12
 Identities = 55/205 (26%), Positives = 90/205 (43%), Gaps = 9/205 (4%)

Query: 170 STEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLV 229
           +TE+    L       F+ G ET   TL      L   P ++  ++EE+           
Sbjct: 283 NTEFYLKNLVMTTLNLFIGGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPK 342

Query: 230 YENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVN 289
           +E+  ++ Y++ V++E  R      F D I              +   L  G  +Y  + 
Sbjct: 343 FEDRAKMPYMEAVIHEIQR------FGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLG 396

Query: 290 SIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRL 349
           S+  DP ++  P+ F P+ FL+E     K   F+PF +G R C G   A ME+ +    +
Sbjct: 397 SVLRDPSFFSNPQDFNPQHFLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTV 456

Query: 350 MLNFKVLKCAKTLDPIKMSP--VGF 372
           M NF+ LK +++   I +SP  VGF
Sbjct: 457 MQNFR-LKSSQSPKDIDVSPKHVGF 480


>BC096253-1|AAH96253.3|  494|Homo sapiens cytochrome P450, family 2,
           subfamily A, polypeptide 6 protein.
          Length = 494

 Score = 72.1 bits (169), Expect = 3e-12
 Identities = 55/205 (26%), Positives = 90/205 (43%), Gaps = 9/205 (4%)

Query: 170 STEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLV 229
           +TE+    L       F+ G ET   TL      L   P ++  ++EE+           
Sbjct: 283 NTEFYLKNLVMTTLNLFIGGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPK 342

Query: 230 YENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVN 289
           +E+  ++ Y++ V++E  R      F D I              +   L  G  +Y  + 
Sbjct: 343 FEDRAKMPYMEAVIHEIQR------FGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLG 396

Query: 290 SIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRL 349
           S+  DP ++  P+ F P+ FL+E     K   F+PF +G R C G   A ME+ +    +
Sbjct: 397 SVLRDPSFFSNPQDFNPQHFLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTV 456

Query: 350 MLNFKVLKCAKTLDPIKMSP--VGF 372
           M NF+ LK +++   I +SP  VGF
Sbjct: 457 MQNFR-LKSSQSPKDIDVSPKHVGF 480


>X54741-1|CAA38539.1|  503|Homo sapiens aldosterone  synthase
           (P-450aldo) protein.
          Length = 503

 Score = 71.7 bits (168), Expect = 4e-12
 Identities = 50/187 (26%), Positives = 87/187 (46%), Gaps = 8/187 (4%)

Query: 169 LSTEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNL 228
           L  E +   + A          +TT   L+  + ELA +P +Q IL +E  A   +    
Sbjct: 295 LKAELSLEAIKANSMELTAGSVDTTAFPLLMTLFELARNPDVQQILRQESLAAAASISEH 354

Query: 229 VYENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTV 288
             +   EL  L   L ET+R +   +F++R+ +   VL       +   +  G ++   +
Sbjct: 355 PQKATTELPLLRAALKETLRLYPVGLFLERVVSSDLVL-------QNYHIPAGTLVQVFL 407

Query: 289 NSIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFR 348
            S+  +   +  PE++ P+R+LD  +   + F  +PFG G R C+G R A  EM +LL  
Sbjct: 408 YSLGRNAALFPRPERYNPQRWLDI-RGSGRNFHHVPFGFGMRQCLGRRLAEAEMLLLLHH 466

Query: 349 LMLNFKV 355
           ++ +F V
Sbjct: 467 VLKHFLV 473


>D13752-1|BAA02899.1|  503|Homo sapiens steroid 18-hydroxylase
           protein.
          Length = 503

 Score = 71.7 bits (168), Expect = 4e-12
 Identities = 50/187 (26%), Positives = 87/187 (46%), Gaps = 8/187 (4%)

Query: 169 LSTEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNL 228
           L  E +   + A          +TT   L+  + ELA +P +Q IL +E  A   +    
Sbjct: 295 LKAELSLEAIKANSMELTAGSVDTTAFPLLMTLFELARNPDVQQILRQESLAAAASISEH 354

Query: 229 VYENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTV 288
             +   EL  L   L ET+R +   +F++R+ +   VL       +   +  G ++   +
Sbjct: 355 PQKATTELPLLRAALKETLRLYPVGLFLERVVSSDLVL-------QNYHIPAGTLVQVFL 407

Query: 289 NSIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFR 348
            S+  +   +  PE++ P+R+LD  +   + F  +PFG G R C+G R A  EM +LL  
Sbjct: 408 YSLGRNAALFPRPERYNPQRWLDI-RGSGRNFHHVPFGFGMRQCLGRRLAEAEMLLLLHH 466

Query: 349 LMLNFKV 355
           ++ +F V
Sbjct: 467 VLKHFLV 473


>J02843-1|AAA52155.1|  493|Homo sapiens protein ( Human cytochrome
           P450IIE1 (ethanol-inducible) gene, complete cds. ).
          Length = 493

 Score = 70.9 bits (166), Expect = 7e-12
 Identities = 61/189 (32%), Positives = 91/189 (48%), Gaps = 15/189 (7%)

Query: 186 FVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYENIGELKYLDCVLNE 245
           F AG ETT  TL   +  L   P I++ L+EE+            ++  E+ Y+D V++E
Sbjct: 297 FFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRIPAIKDRQEMPYMDAVVHE 356

Query: 246 TMRKWSAAIFVDRICTKPYVLP--PPREGGKPCQLKP-GEVIYNTVNSIHMDPIYYEEPE 302
             R      F+  +   P  LP    R+      L P G V+  T++S+  D   + +PE
Sbjct: 357 IQR------FITLV---PSNLPHEATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPE 407

Query: 303 KFIPERFLDEN-KHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVLKCAKT 361
           KF PE FL+EN K K   + F PF  G R C G   A ME+ +LL  ++ +F +      
Sbjct: 408 KFKPEHFLNENGKFKYSDY-FKPFSTGKRVCAGEGLARMELFLLLCAILQHFNLKPLVDP 466

Query: 362 LDPIKMSPV 370
            D I +SP+
Sbjct: 467 KD-IDLSPI 474


>J02625-1|AAA35743.1|  493|Homo sapiens protein ( Human cytochrome
           P-450j mRNA, complete cds. ).
          Length = 493

 Score = 70.9 bits (166), Expect = 7e-12
 Identities = 61/189 (32%), Positives = 91/189 (48%), Gaps = 15/189 (7%)

Query: 186 FVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYENIGELKYLDCVLNE 245
           F AG ETT  TL   +  L   P I++ L+EE+            ++  E+ Y+D V++E
Sbjct: 297 FFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRIPAIKDRQEMPYMDAVVHE 356

Query: 246 TMRKWSAAIFVDRICTKPYVLP--PPREGGKPCQLKP-GEVIYNTVNSIHMDPIYYEEPE 302
             R      F+  +   P  LP    R+      L P G V+  T++S+  D   + +PE
Sbjct: 357 IQR------FITLV---PSNLPHEATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPE 407

Query: 303 KFIPERFLDEN-KHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVLKCAKT 361
           KF PE FL+EN K K   + F PF  G R C G   A ME+ +LL  ++ +F +      
Sbjct: 408 KFKPEHFLNENGKFKYSDY-FKPFSTGKRVCAGEGLARMELFLLLCAILQHFNLKPLVDP 466

Query: 362 LDPIKMSPV 370
            D I +SP+
Sbjct: 467 KD-IDLSPI 474


>DQ515958-1|ABF47105.1|  493|Homo sapiens cytochrome P450, family 2,
           subfamily E, polypeptide 1 protein.
          Length = 493

 Score = 70.9 bits (166), Expect = 7e-12
 Identities = 61/189 (32%), Positives = 91/189 (48%), Gaps = 15/189 (7%)

Query: 186 FVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYENIGELKYLDCVLNE 245
           F AG ETT  TL   +  L   P I++ L+EE+            ++  E+ Y+D V++E
Sbjct: 297 FFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRIPAIKDRQEMPYMDAVVHE 356

Query: 246 TMRKWSAAIFVDRICTKPYVLP--PPREGGKPCQLKP-GEVIYNTVNSIHMDPIYYEEPE 302
             R      F+  +   P  LP    R+      L P G V+  T++S+  D   + +PE
Sbjct: 357 IQR------FITLV---PSNLPHEATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPE 407

Query: 303 KFIPERFLDEN-KHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVLKCAKT 361
           KF PE FL+EN K K   + F PF  G R C G   A ME+ +LL  ++ +F +      
Sbjct: 408 KFKPEHFLNENGKFKYSDY-FKPFSTGKRVCAGEGLARMELFLLLCAILQHFNLKPLVDP 466

Query: 362 LDPIKMSPV 370
            D I +SP+
Sbjct: 467 KD-IDLSPI 474


>DQ149222-1|AAZ77710.1|  493|Homo sapiens cytochrome P450 2E1
           protein.
          Length = 493

 Score = 70.9 bits (166), Expect = 7e-12
 Identities = 61/189 (32%), Positives = 91/189 (48%), Gaps = 15/189 (7%)

Query: 186 FVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYENIGELKYLDCVLNE 245
           F AG ETT  TL   +  L   P I++ L+EE+            ++  E+ Y+D V++E
Sbjct: 297 FFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRIPAIKDRQEMPYMDAVVHE 356

Query: 246 TMRKWSAAIFVDRICTKPYVLP--PPREGGKPCQLKP-GEVIYNTVNSIHMDPIYYEEPE 302
             R      F+  +   P  LP    R+      L P G V+  T++S+  D   + +PE
Sbjct: 357 IQR------FITLV---PSNLPHEATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPE 407

Query: 303 KFIPERFLDEN-KHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVLKCAKT 361
           KF PE FL+EN K K   + F PF  G R C G   A ME+ +LL  ++ +F +      
Sbjct: 408 KFKPEHFLNENGKFKYSDY-FKPFSTGKRVCAGEGLARMELFLLLCAILQHFNLKPLVDP 466

Query: 362 LDPIKMSPV 370
            D I +SP+
Sbjct: 467 KD-IDLSPI 474


>AL161645-2|CAH70047.1|  493|Homo sapiens cytochrome P450, family 2,
           subfamily E, polypeptide 1 protein.
          Length = 493

 Score = 70.9 bits (166), Expect = 7e-12
 Identities = 61/189 (32%), Positives = 91/189 (48%), Gaps = 15/189 (7%)

Query: 186 FVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYENIGELKYLDCVLNE 245
           F AG ETT  TL   +  L   P I++ L+EE+            ++  E+ Y+D V++E
Sbjct: 297 FFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRIPAIKDRQEMPYMDAVVHE 356

Query: 246 TMRKWSAAIFVDRICTKPYVLP--PPREGGKPCQLKP-GEVIYNTVNSIHMDPIYYEEPE 302
             R      F+  +   P  LP    R+      L P G V+  T++S+  D   + +PE
Sbjct: 357 IQR------FITLV---PSNLPHEATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPE 407

Query: 303 KFIPERFLDEN-KHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVLKCAKT 361
           KF PE FL+EN K K   + F PF  G R C G   A ME+ +LL  ++ +F +      
Sbjct: 408 KFKPEHFLNENGKFKYSDY-FKPFSTGKRVCAGEGLARMELFLLLCAILQHFNLKPLVDP 466

Query: 362 LDPIKMSPV 370
            D I +SP+
Sbjct: 467 KD-IDLSPI 474


>AF182276-1|AAF13601.1|  493|Homo sapiens cytochrome P450-2E1
           protein.
          Length = 493

 Score = 70.9 bits (166), Expect = 7e-12
 Identities = 61/189 (32%), Positives = 91/189 (48%), Gaps = 15/189 (7%)

Query: 186 FVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYENIGELKYLDCVLNE 245
           F AG ETT  TL   +  L   P I++ L+EE+            ++  E+ Y+D V++E
Sbjct: 297 FFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRIPAIKDRQEMPYMDAVVHE 356

Query: 246 TMRKWSAAIFVDRICTKPYVLP--PPREGGKPCQLKP-GEVIYNTVNSIHMDPIYYEEPE 302
             R      F+  +   P  LP    R+      L P G V+  T++S+  D   + +PE
Sbjct: 357 IQR------FITLV---PSNLPHEATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPE 407

Query: 303 KFIPERFLDEN-KHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVLKCAKT 361
           KF PE FL+EN K K   + F PF  G R C G   A ME+ +LL  ++ +F +      
Sbjct: 408 KFKPEHFLNENGKFKYSDY-FKPFSTGKRVCAGEGLARMELFLLLCAILQHFNLKPLVDP 466

Query: 362 LDPIKMSPV 370
            D I +SP+
Sbjct: 467 KD-IDLSPI 474


>AF182275-1|AAF13600.1|  494|Homo sapiens cytochrome P450-2A6
           protein.
          Length = 494

 Score = 70.9 bits (166), Expect = 7e-12
 Identities = 52/200 (26%), Positives = 87/200 (43%), Gaps = 7/200 (3%)

Query: 170 STEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLV 229
           +TE+    L       F+ G ET   TL      L   P ++  ++EE+           
Sbjct: 283 NTEFYLKNLVMTTLNLFIGGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPK 342

Query: 230 YENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVN 289
           +E+  ++ Y++ V++E  R      F D I              +   L  G  +Y  + 
Sbjct: 343 FEDRAKMPYMEAVIHEIQR------FGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLG 396

Query: 290 SIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRL 349
           S+  DP ++  P+ F P+ FL+E     K   F+PF +G R C G   A ME+ +    +
Sbjct: 397 SVLRDPSFFSNPQDFNPQHFLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTV 456

Query: 350 MLNFKVLKCAKTLDPIKMSP 369
           M NF+ LK +++   I +SP
Sbjct: 457 MQNFR-LKSSQSPKDIDVSP 475


>AF084225-1|AAD13753.1|  462|Homo sapiens cytochrome P450 2E1
           protein.
          Length = 462

 Score = 70.9 bits (166), Expect = 7e-12
 Identities = 61/189 (32%), Positives = 91/189 (48%), Gaps = 15/189 (7%)

Query: 186 FVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYENIGELKYLDCVLNE 245
           F AG ETT  TL   +  L   P I++ L+EE+            ++  E+ Y+D V++E
Sbjct: 266 FFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRIPAIKDRQEMPYMDAVVHE 325

Query: 246 TMRKWSAAIFVDRICTKPYVLP--PPREGGKPCQLKP-GEVIYNTVNSIHMDPIYYEEPE 302
             R      F+  +   P  LP    R+      L P G V+  T++S+  D   + +PE
Sbjct: 326 IQR------FITLV---PSNLPHEATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPE 376

Query: 303 KFIPERFLDEN-KHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVLKCAKT 361
           KF PE FL+EN K K   + F PF  G R C G   A ME+ +LL  ++ +F +      
Sbjct: 377 KFKPEHFLNENGKFKYSDY-FKPFSTGKRVCAGEGLARMELFLLLCAILQHFNLKPLVDP 435

Query: 362 LDPIKMSPV 370
            D I +SP+
Sbjct: 436 KD-IDLSPI 443


>BC067433-1|AAH67433.1|  493|Homo sapiens cytochrome P450, family 2,
           subfamily E, polypeptide 1 protein.
          Length = 493

 Score = 70.5 bits (165), Expect = 9e-12
 Identities = 61/189 (32%), Positives = 90/189 (47%), Gaps = 15/189 (7%)

Query: 186 FVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYENIGELKYLDCVLNE 245
           F AG ETT  TL   +  L   P I++ L+EE+            ++  E+ Y+D V+ E
Sbjct: 297 FFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRIPAIKDRQEMPYMDAVVRE 356

Query: 246 TMRKWSAAIFVDRICTKPYVLP--PPREGGKPCQLKP-GEVIYNTVNSIHMDPIYYEEPE 302
             R      F+  +   P  LP    R+      L P G V+  T++S+  D   + +PE
Sbjct: 357 IQR------FITLV---PSNLPHEATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPE 407

Query: 303 KFIPERFLDEN-KHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVLKCAKT 361
           KF PE FL+EN K K   + F PF  G R C G   A ME+ +LL  ++ +F +      
Sbjct: 408 KFKPEHFLNENGKFKYSDY-FKPFSTGKRVCAGEGLARMELFLLLCAILQHFNLKPLVDP 466

Query: 362 LDPIKMSPV 370
            D I +SP+
Sbjct: 467 KD-IDLSPI 474


>AL358613-3|CAH72804.1|  428|Homo sapiens cytochrome P450, family
           26, subfamily A, polypeptide 1 protein.
          Length = 428

 Score = 70.5 bits (165), Expect = 9e-12
 Identities = 61/200 (30%), Positives = 94/200 (47%), Gaps = 18/200 (9%)

Query: 160 RDMIQLLMQLSTEWTET----ELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILY 215
           +D +QLL++ S E  E      L          G ETT +   + I  L L PH+   + 
Sbjct: 199 KDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVR 258

Query: 216 EELKA----FKETKGN-LVYENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPR 270
           EELK+     K  + N L  E + +LKY+ CV+ ET+R         R+  K + L    
Sbjct: 259 EELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFEL---- 314

Query: 271 EGGKPCQLKPG-EVIYNTVNSIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGP 329
                 Q+  G  VIY+  ++  +  I+  + E+F P+RF+  +      F+F+PFG G 
Sbjct: 315 ---NGYQIPKGWNVIYSICDTHDVAEIFTNK-EEFNPDRFMLPHPEDASRFSFIPFGGGL 370

Query: 330 RYCIGSRFALMEMKILLFRL 349
           R C+G  FA + +KI    L
Sbjct: 371 RSCVGKEFAKILLKIFTVEL 390


>AL358613-2|CAH72803.1|  497|Homo sapiens cytochrome P450, family
           26, subfamily A, polypeptide 1 protein.
          Length = 497

 Score = 70.5 bits (165), Expect = 9e-12
 Identities = 61/200 (30%), Positives = 94/200 (47%), Gaps = 18/200 (9%)

Query: 160 RDMIQLLMQLSTEWTET----ELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILY 215
           +D +QLL++ S E  E      L          G ETT +   + I  L L PH+   + 
Sbjct: 268 KDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVR 327

Query: 216 EELKA----FKETKGN-LVYENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPR 270
           EELK+     K  + N L  E + +LKY+ CV+ ET+R         R+  K + L    
Sbjct: 328 EELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFEL---- 383

Query: 271 EGGKPCQLKPG-EVIYNTVNSIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGP 329
                 Q+  G  VIY+  ++  +  I+  + E+F P+RF+  +      F+F+PFG G 
Sbjct: 384 ---NGYQIPKGWNVIYSICDTHDVAEIFTNK-EEFNPDRFMLPHPEDASRFSFIPFGGGL 439

Query: 330 RYCIGSRFALMEMKILLFRL 349
           R C+G  FA + +KI    L
Sbjct: 440 RSCVGKEFAKILLKIFTVEL 459


>AF005418-1|AAB88881.1|  497|Homo sapiens retinoic acid hydroxylase
           protein.
          Length = 497

 Score = 70.5 bits (165), Expect = 9e-12
 Identities = 61/200 (30%), Positives = 94/200 (47%), Gaps = 18/200 (9%)

Query: 160 RDMIQLLMQLSTEWTET----ELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILY 215
           +D +QLL++ S E  E      L          G ETT +   + I  L L PH+   + 
Sbjct: 268 KDALQLLIEHSWERGERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVR 327

Query: 216 EELKA----FKETKGN-LVYENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPR 270
           EELK+     K  + N L  E + +LKY+ CV+ ET+R         R+  K + L    
Sbjct: 328 EELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFEL---- 383

Query: 271 EGGKPCQLKPG-EVIYNTVNSIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGP 329
                 Q+  G  VIY+  ++  +  I+  + E+F P+RF+  +      F+F+PFG G 
Sbjct: 384 ---NGYQIPKGWNVIYSICDTHDVAEIFTNK-EEFNPDRFMLPHPEDASRFSFIPFGGGL 439

Query: 330 RYCIGSRFALMEMKILLFRL 349
           R C+G  FA + +KI    L
Sbjct: 440 RSCVGKEFAKILLKIFTVEL 459


>M61858-1|AAA52145.1|  370|Homo sapiens CYP2C17 protein.
          Length = 370

 Score = 69.3 bits (162), Expect = 2e-11
 Identities = 52/186 (27%), Positives = 84/186 (45%), Gaps = 8/186 (4%)

Query: 171 TEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVY 230
           +E+T   L A +   F AG ETT  TL   +  L   P +   + EE++       +   
Sbjct: 160 SEFTVESLIATVTDMFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVVGRNRSPCM 219

Query: 231 ENIGELKYLDCVLNETMRKWSAAIFVDRICTK-PYVLPPPREGGKPCQLKPGEVIYNTVN 289
           ++   + Y D V++E  R      ++D I T  P+ +    +  +   +  G  I  ++ 
Sbjct: 220 QDRSHMPYTDAVVHEVQR------YIDLIPTSLPHAVTCDVKF-RNYLIPKGTTILTSLT 272

Query: 290 SIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRL 349
           S+  D   +  PE F P  FLDE  +  K   FMPF  G R C+G   A ME+ + L  +
Sbjct: 273 SVLHDNKEFPNPEMFDPRHFLDEGGNFKKSNYFMPFSAGKRICVGEGLARMELFLFLTFI 332

Query: 350 MLNFKV 355
           + NF +
Sbjct: 333 LQNFNL 338


>AY513608-1|AAR90939.1|  494|Homo sapiens cytochrome P450 2A13
           variant 5 protein.
          Length = 494

 Score = 68.9 bits (161), Expect = 3e-11
 Identities = 54/205 (26%), Positives = 87/205 (42%), Gaps = 9/205 (4%)

Query: 170 STEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLV 229
           +TE+    L       F AG ET   TL      L   P ++  ++EE+           
Sbjct: 283 NTEFYLKNLVMTTLNLFFAGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPK 342

Query: 230 YENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVN 289
           +E+  ++ Y + V++E  R      F D +              +   L  G  ++  + 
Sbjct: 343 FEDRAKMPYTEAVIHEIQR------FGDMLPMGLAHRVNKDTKFRDFFLPKGTEVFPMLG 396

Query: 290 SIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRL 349
           S+  DP ++  P  F P+ FLD+     K   F+PF +G RYC G   A ME+ +    +
Sbjct: 397 SVLRDPRFFSNPRDFNPQHFLDKKGQFKKSDAFVPFSIGKRYCFGEGLARMELFLFFTTI 456

Query: 350 MLNFKVLKCAKTLDPIKMSP--VGF 372
           M NF+  K  ++   I +SP  VGF
Sbjct: 457 MQNFR-FKSPQSPKDIDVSPKHVGF 480


>AY513606-1|AAR90937.1|  494|Homo sapiens cytochrome P450 2A13
           variant 3 protein.
          Length = 494

 Score = 68.9 bits (161), Expect = 3e-11
 Identities = 54/205 (26%), Positives = 87/205 (42%), Gaps = 9/205 (4%)

Query: 170 STEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLV 229
           +TE+    L       F AG ET   TL      L   P ++  ++EE+           
Sbjct: 283 NTEFYLKNLVMTTLNLFFAGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPK 342

Query: 230 YENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVN 289
           +E+  ++ Y + V++E  R      F D +              +   L  G  ++  + 
Sbjct: 343 FEDRAKMPYTEAVIHEIQR------FGDMLPMGLAHRVNKDTKFRDFFLPKGTEVFPMLG 396

Query: 290 SIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRL 349
           S+  DP ++  P  F P+ FLD+     K   F+PF +G RYC G   A ME+ +    +
Sbjct: 397 SVLRDPRFFSNPRDFNPQHFLDKKGQFKKSDAFVPFSIGKRYCFGEGLARMELFLFFTTI 456

Query: 350 MLNFKVLKCAKTLDPIKMSP--VGF 372
           M NF+  K  ++   I +SP  VGF
Sbjct: 457 MQNFR-FKSPQSPKDIDVSPKHVGF 480


>AY513605-1|AAR90936.1|  494|Homo sapiens cytochrome P450 2A13
           variant 2 protein.
          Length = 494

 Score = 68.9 bits (161), Expect = 3e-11
 Identities = 54/205 (26%), Positives = 87/205 (42%), Gaps = 9/205 (4%)

Query: 170 STEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLV 229
           +TE+    L       F AG ET   TL      L   P ++  ++EE+           
Sbjct: 283 NTEFYLKNLVMTTLNLFFAGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPK 342

Query: 230 YENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVN 289
           +E+  ++ Y + V++E  R      F D +              +   L  G  ++  + 
Sbjct: 343 FEDRAKMPYTEAVIHEIQR------FGDMLPMGLAHRVNKDTKFRDFFLPKGTEVFPMLG 396

Query: 290 SIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRL 349
           S+  DP ++  P  F P+ FLD+     K   F+PF +G RYC G   A ME+ +    +
Sbjct: 397 SVLRDPRFFSNPRDFNPQHFLDKKGQFKKSDAFVPFSIGKRYCFGEGLARMELFLFFTTI 456

Query: 350 MLNFKVLKCAKTLDPIKMSP--VGF 372
           M NF+  K  ++   I +SP  VGF
Sbjct: 457 MQNFR-FKSPQSPKDIDVSPKHVGF 480


>AY513604-1|AAR90935.1|  494|Homo sapiens cytochrome P450 2A13
           variant 1 protein.
          Length = 494

 Score = 68.9 bits (161), Expect = 3e-11
 Identities = 54/205 (26%), Positives = 87/205 (42%), Gaps = 9/205 (4%)

Query: 170 STEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLV 229
           +TE+    L       F AG ET   TL      L   P ++  ++EE+           
Sbjct: 283 NTEFYLKNLVMTTLNLFFAGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPK 342

Query: 230 YENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVN 289
           +E+  ++ Y + V++E  R      F D +              +   L  G  ++  + 
Sbjct: 343 FEDRAKMPYTEAVIHEIQR------FGDMLPMGLAHRVNKDTKFRDFFLPKGTEVFPMLG 396

Query: 290 SIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRL 349
           S+  DP ++  P  F P+ FLD+     K   F+PF +G RYC G   A ME+ +    +
Sbjct: 397 SVLRDPRFFSNPRDFNPQHFLDKKGQFKKSDAFVPFSIGKRYCFGEGLARMELFLFFTTI 456

Query: 350 MLNFKVLKCAKTLDPIKMSP--VGF 372
           M NF+  K  ++   I +SP  VGF
Sbjct: 457 MQNFR-FKSPQSPKDIDVSPKHVGF 480


>AF209774-1|AAG35775.1|  494|Homo sapiens cytochrome P450 2A13
           protein.
          Length = 494

 Score = 68.9 bits (161), Expect = 3e-11
 Identities = 54/205 (26%), Positives = 87/205 (42%), Gaps = 9/205 (4%)

Query: 170 STEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLV 229
           +TE+    L       F AG ET   TL      L   P ++  ++EE+           
Sbjct: 283 NTEFYLKNLVMTTLNLFFAGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPK 342

Query: 230 YENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVN 289
           +E+  ++ Y + V++E  R      F D +              +   L  G  ++  + 
Sbjct: 343 FEDRAKMPYTEAVIHEIQR------FGDMLPMGLAHRVNKDTKFRDFFLPKGTEVFPMLG 396

Query: 290 SIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRL 349
           S+  DP ++  P  F P+ FLD+     K   F+PF +G RYC G   A ME+ +    +
Sbjct: 397 SVLRDPRFFSNPRDFNPQHFLDKKGQFKKSDAFVPFSIGKRYCFGEGLARMELFLFFTTI 456

Query: 350 MLNFKVLKCAKTLDPIKMSP--VGF 372
           M NF+  K  ++   I +SP  VGF
Sbjct: 457 MQNFR-FKSPQSPKDIDVSPKHVGF 480


>M32881-1|AAA35741.1|  503|Homo sapiens protein ( Human steroid
           11-beta-hydroxylase-like-enzyme (CYP11B2) gene, exon 9.
           ).
          Length = 503

 Score = 68.5 bits (160), Expect = 4e-11
 Identities = 49/187 (26%), Positives = 85/187 (45%), Gaps = 8/187 (4%)

Query: 169 LSTEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNL 228
           L  E +   + A          +TT   L+  + ELA +P +Q IL +E  A   +    
Sbjct: 295 LKAELSLEAIKANSMELTAGSVDTTAFPLLMTLFELARNPDVQQILRKESLAAAASISEH 354

Query: 229 VYENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTV 288
             +   EL  L   L ET+R +   +F++R+ +   VL       +   +  G ++   +
Sbjct: 355 PQKATTELPLLRAALKETLRLYPVGLFLERVVSSDLVL-------QNYHIPAGTLVQVFL 407

Query: 289 NSIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFR 348
            S+  +   +  PE++ P+R+LD  +   +    +PFG G R C+G R A  EM +LL  
Sbjct: 408 YSLGRNAALFPRPERYNPQRWLDI-RGSGRNLHHVPFGFGMRQCLGRRLAEAEMLLLLHH 466

Query: 349 LMLNFKV 355
           ++  F V
Sbjct: 467 VLKRFLV 473


>D13705-1|BAA02864.1|  521|Homo sapiens fatty acid omega-hydroxylase
           protein.
          Length = 521

 Score = 68.5 bits (160), Expect = 4e-11
 Identities = 45/192 (23%), Positives = 89/192 (46%), Gaps = 9/192 (4%)

Query: 154 KNKVERRDMIQLL-MQLSTEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQD 212
           K  ++  D++ L  M+  +  ++ +L A++  F   G +TT + +   ++ LA  P  Q+
Sbjct: 287 KRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQE 346

Query: 213 ILYEELKAFKETKGNLVYENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREG 272
              EE+ +      ++ + ++ ++ Y    + E +R +     + R  + P   P  R  
Sbjct: 347 RCREEIHSLLGDGASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGR-- 404

Query: 273 GKPCQLKPGEVIYNTVNSIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYC 332
                L  G ++  ++  +H +P  +  PE F P RF   +        F+PF  G R C
Sbjct: 405 ----SLPKGIMVLLSIYGLHHNPKVWPNPEVFDPFRFAPGSAQ--HSHAFLPFSGGSRNC 458

Query: 333 IGSRFALMEMKI 344
           IG +FA+ E+K+
Sbjct: 459 IGKQFAMNELKV 470


>BC067435-1|AAH67435.1|  493|Homo sapiens cytochrome P450, family 2,
           subfamily E, polypeptide 1 protein.
          Length = 493

 Score = 68.5 bits (160), Expect = 4e-11
 Identities = 60/189 (31%), Positives = 90/189 (47%), Gaps = 15/189 (7%)

Query: 186 FVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYENIGELKYLDCVLNE 245
           F AG ETT  TL   +  L   P I++ L+EE+            ++  E+ Y+D V++E
Sbjct: 297 FFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRIPAIKDRQEMPYMDAVVHE 356

Query: 246 TMRKWSAAIFVDRICTKPYVLP--PPREGGKPCQLKP-GEVIYNTVNSIHMDPIYYEEPE 302
             R      F+  +   P  LP    R+      L P G V+  T++S+  D   + +PE
Sbjct: 357 IQR------FITLV---PSNLPHEATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPE 407

Query: 303 KFIPERFLDEN-KHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVLKCAKT 361
           KF PE FL+EN K K   + F PF  G R C G   A  E+ +LL  ++ +F +      
Sbjct: 408 KFKPEHFLNENGKFKYSDY-FKPFSTGKRVCAGEGLARTELFLLLCAILQHFNLKPLVDP 466

Query: 362 LDPIKMSPV 370
            D I +SP+
Sbjct: 467 KD-IDLSPI 474


>AY513609-1|AAR90940.1|  494|Homo sapiens cytochrome P450 2A13
           variant 6 protein.
          Length = 494

 Score = 68.5 bits (160), Expect = 4e-11
 Identities = 54/205 (26%), Positives = 87/205 (42%), Gaps = 9/205 (4%)

Query: 170 STEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLV 229
           +TE+    L       F AG ET   TL      L   P ++  ++EE+           
Sbjct: 283 NTEFYLKNLVMTTLNLFFAGTETVSTTLRYGFLLLMKHPELEAKVHEEIDRVIGKNRQPK 342

Query: 230 YENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVN 289
           +E+  ++ Y + V++E  R      F D +              +   L  G  ++  + 
Sbjct: 343 FEDRAKMPYTEAVIHEIQR------FGDMLPMGLAHRVNKDTKFRDFFLPKGTEVFPMLG 396

Query: 290 SIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRL 349
           S+  DP ++  P  F P+ FLD+     K   F+PF +G RYC G   A ME+ +    +
Sbjct: 397 SVLRDPRFFSNPRDFNPQHFLDKKGQFKKSDAFVPFSIGKRYCFGEGLARMELFLFFTTI 456

Query: 350 MLNFKVLKCAKTLDPIKMSP--VGF 372
           M NF+  K  ++   I +SP  VGF
Sbjct: 457 MQNFR-FKSPQSPKDIDVSPKHVGF 480


>AL135960-10|CAI19737.1|  519|Homo sapiens cytochrome P450, family
           4, subfamily A, polypeptide 22 protein.
          Length = 519

 Score = 68.5 bits (160), Expect = 4e-11
 Identities = 50/216 (23%), Positives = 98/216 (45%), Gaps = 10/216 (4%)

Query: 154 KNKVERRDMIQLL-MQLSTEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQD 212
           K  ++  D++ L  M+  +  ++ +L A++  F   G +TT + +   ++ LA  P  Q+
Sbjct: 286 KRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQE 345

Query: 213 ILYEELKAFKETKGNLVYENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREG 272
              EE+        ++ + ++ ++ Y    + E +R +     + R  + P   P  R  
Sbjct: 346 RCREEIHGLLGDGASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGR-- 403

Query: 273 GKPCQLKPGEVIYNTVNSIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYC 332
                L  G ++  ++  +H +P  +   E F P RF   +        F+PF  G R C
Sbjct: 404 ----SLPKGIMVLLSIYGLHHNPKVWPNLEVFDPSRFAPGSAQ--HSHAFLPFSGGSRNC 457

Query: 333 IGSRFALMEMKILLFRLMLNFKVLKCAKTLDPIKMS 368
           IG +FA+ ++K+     +L F++L    T  PI M+
Sbjct: 458 IGKQFAMNQLKVARALTLLRFELLP-DPTRIPIPMA 492


>AF208532-1|AAF76722.1|  519|Homo sapiens fatty acid
           omega-hydroxylase CYP4A11 protein.
          Length = 519

 Score = 68.1 bits (159), Expect = 5e-11
 Identities = 46/204 (22%), Positives = 93/204 (45%), Gaps = 9/204 (4%)

Query: 154 KNKVERRDMIQLL-MQLSTEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQD 212
           K  ++  D++ L  M+  +  ++ +L A++  F   G +TT + +   ++ LA  P  Q+
Sbjct: 286 KRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQE 345

Query: 213 ILYEELKAFKETKGNLVYENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREG 272
              EE+        ++ + ++ ++ Y    + E +R +     + R  + P   P  R  
Sbjct: 346 RCREEIHGLLGDGASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGR-- 403

Query: 273 GKPCQLKPGEVIYNTVNSIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYC 332
                L  G ++  ++  +H +P  +   E F P RF   +        F+PF  G R C
Sbjct: 404 ----SLPKGIMVLLSIYGLHHNPKVWPNLEVFDPSRFAPGSAQ--HSHAFLPFSGGSRNC 457

Query: 333 IGSRFALMEMKILLFRLMLNFKVL 356
           IG +FA+ ++K+     +L F++L
Sbjct: 458 IGKQFAMNQLKVARALTLLRFELL 481


>X05367-1|CAA28965.1|  521|Homo sapiens desmolase protein.
          Length = 521

 Score = 67.7 bits (158), Expect = 7e-11
 Identities = 49/179 (27%), Positives = 87/179 (48%), Gaps = 8/179 (4%)

Query: 177 ELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYENIGEL 236
           ++ A +      G +TT  TL   ++E+A +  +QD+L  E+ A +      +   +  +
Sbjct: 315 DIKANVTEMLAGGVDTTSMTLQWHLYEMARNLKVQDMLRAEVLAARHQAQGDMATMLQLV 374

Query: 237 KYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHMDPI 296
             L   + ET+R    ++ + R      VL   R+   P +      IY    ++  +P 
Sbjct: 375 PLLKASIKETLRLHPISVTLQRYLVNDLVL---RDYMIPAKTLVQVAIY----ALGREPT 427

Query: 297 YYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKV 355
           ++ +PE F P R+L ++K+ I  F  + FG G R C+G R A +EM I L  ++ NF+V
Sbjct: 428 FFFDPENFDPTRWLSKDKN-ITYFRNLGFGWGVRQCLGRRIAELEMTIFLINMLENFRV 485


>M28253-1|AAA36404.1|  239|Homo sapiens cytochrome P-450-scc
           protein.
          Length = 239

 Score = 67.7 bits (158), Expect = 7e-11
 Identities = 49/179 (27%), Positives = 87/179 (48%), Gaps = 8/179 (4%)

Query: 177 ELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYENIGEL 236
           ++ A +      G +TT  TL   ++E+A +  +QD+L  E+ A +      +   +  +
Sbjct: 33  DIKANVTEMLAGGVDTTSMTLQWHLYEMARNLKVQDMLRAEVLAARHQAQGDMATMLQLV 92

Query: 237 KYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHMDPI 296
             L   + ET+R    ++ + R      VL   R+   P +      IY    ++  +P 
Sbjct: 93  PLLKASIKETLRLHPISVTLQRYLVNDLVL---RDYMIPAKTLVQVAIY----ALGREPT 145

Query: 297 YYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKV 355
           ++ +PE F P R+L ++K+ I  F  + FG G R C+G R A +EM I L  ++ NF+V
Sbjct: 146 FFFDPENFDPTRWLSKDKN-ITYFRNLGFGWGVRQCLGRRIAELEMTIFLINMLENFRV 203


>M14565-1|AAA52162.1|  521|Homo sapiens CYP11A protein.
          Length = 521

 Score = 67.7 bits (158), Expect = 7e-11
 Identities = 49/179 (27%), Positives = 87/179 (48%), Gaps = 8/179 (4%)

Query: 177 ELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYENIGEL 236
           ++ A +      G +TT  TL   ++E+A +  +QD+L  E+ A +      +   +  +
Sbjct: 315 DIKANVTEMLAGGVDTTSMTLQWHLYEMARNLKVQDMLRAEVLAARHQAQGDMATMLQLV 374

Query: 237 KYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHMDPI 296
             L   + ET+R    ++ + R      VL   R+   P +      IY    ++  +P 
Sbjct: 375 PLLKASIKETLRLHPISVTLQRYLVNDLVL---RDYMIPAKTLVQVAIY----ALGREPT 427

Query: 297 YYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKV 355
           ++ +PE F P R+L ++K+ I  F  + FG G R C+G R A +EM I L  ++ NF+V
Sbjct: 428 FFFDPENFDPTRWLSKDKN-ITYFRNLGFGWGVRQCLGRRIAELEMTIFLINMLENFRV 485


>BC032329-1|AAH32329.1|  521|Homo sapiens cytochrome P450, family
           11, subfamily A, polypeptide 1 protein.
          Length = 521

 Score = 67.7 bits (158), Expect = 7e-11
 Identities = 49/179 (27%), Positives = 87/179 (48%), Gaps = 8/179 (4%)

Query: 177 ELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYENIGEL 236
           ++ A +      G +TT  TL   ++E+A +  +QD+L  E+ A +      +   +  +
Sbjct: 315 DIKANVTEMLAGGVDTTSMTLQWHLYEMARNLKVQDMLRAEVLAARHQAQGDMATMLQLV 374

Query: 237 KYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHMDPI 296
             L   + ET+R    ++ + R      VL   R+   P +      IY    ++  +P 
Sbjct: 375 PLLKASIKETLRLHPISVTLQRYLVNDLVL---RDYMIPAKTLVQVAIY----ALGREPT 427

Query: 297 YYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKV 355
           ++ +PE F P R+L ++K+ I  F  + FG G R C+G R A +EM I L  ++ NF+V
Sbjct: 428 FFFDPENFDPTRWLSKDKN-ITYFRNLGFGWGVRQCLGRRIAELEMTIFLINMLENFRV 485


>M80646-1|AAA60617.1|  460|Homo sapiens thromboxane synthase
           protein.
          Length = 460

 Score = 66.9 bits (156), Expect = 1e-10
 Identities = 44/137 (32%), Positives = 67/137 (48%), Gaps = 8/137 (5%)

Query: 174 TETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYENI 233
           T  E+  Q F+F +AG+E   NTL    + LA +P  Q+ L  E+  FKE      + ++
Sbjct: 328 TVDEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSL 387

Query: 234 GE-LKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIH 292
            E L YLD V+ ET+R +  A    R   +   +   R       +  G V+   V ++H
Sbjct: 388 EEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQR-------IPAGAVLEMAVGALH 440

Query: 293 MDPIYYEEPEKFIPERF 309
            DP ++  PE F PER+
Sbjct: 441 HDPEHWPSPETFNPERY 457



 Score = 60.9 bits (141), Expect = 8e-09
 Identities = 30/87 (34%), Positives = 54/87 (62%), Gaps = 2/87 (2%)

Query: 37  IFIRDPEIIKHVTVKEFDHFVNNKDLSPEGEESILKNSLIMLKDEKWRKMRAALSPAFTA 96
           I I +P++IK V V+ F +F N   ++   E   + +S++ L+D++W ++R AL  AF+ 
Sbjct: 89  IVISEPDMIKQVLVENFSNFTNR--MASGLEFKSVADSVLFLRDKRWEEVRGALMSAFSP 146

Query: 97  SKMREMVPLITEISHNIVEYLKDHFPS 123
            K+ EMVPLI++    ++ +LK +  S
Sbjct: 147 EKLNEMVPLISQACDLLLAHLKRYAES 173


>X65962-1|CAA46778.1|  356|Homo sapiens cytochrome P-450 II C
           protein.
          Length = 356

 Score = 66.5 bits (155), Expect = 2e-10
 Identities = 51/186 (27%), Positives = 82/186 (44%), Gaps = 8/186 (4%)

Query: 171 TEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVY 230
           +E+T   L         AG ETT  TL   +  L   P +   + EE++       +   
Sbjct: 146 SEFTIENLVITAADLLGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVVGRNRSPCM 205

Query: 231 ENIGELKYLDCVLNETMRKWSAAIFVDRICTK-PYVLPPPREGGKPCQLKPGEVIYNTVN 289
           ++ G + Y D V++E  R      ++D I T  P+ +    +  +   +  G  I  ++ 
Sbjct: 206 QDRGHMPYTDAVVHEVQR------YIDLIPTSLPHAVTCDIKF-RNYLIPKGTTILTSLT 258

Query: 290 SIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRL 349
           S+  D   +  PE F P  FLDE  +  K   FMPF  G R C+G   A ME+ + L  +
Sbjct: 259 SVLHDNKEFPNPEMFDPRHFLDEGGNFKKSNYFMPFSAGKRICVGEGLARMELFLFLTFI 318

Query: 350 MLNFKV 355
           + NF +
Sbjct: 319 LQNFNL 324


>L07093-1|AAA36660.1|  468|Homo sapiens cytochrome P450 protein.
          Length = 468

 Score = 66.5 bits (155), Expect = 2e-10
 Identities = 51/186 (27%), Positives = 82/186 (44%), Gaps = 8/186 (4%)

Query: 171 TEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVY 230
           +E+T   L         AG ETT  TL   +  L   P +   + EE++       +   
Sbjct: 258 SEFTIENLVITAADLLGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVVGRNRSPCM 317

Query: 231 ENIGELKYLDCVLNETMRKWSAAIFVDRICTK-PYVLPPPREGGKPCQLKPGEVIYNTVN 289
           ++ G + Y D V++E  R      ++D I T  P+ +    +  +   +  G  I  ++ 
Sbjct: 318 QDRGHMPYTDAVVHEVQR------YIDLIPTSLPHAVTCDVKF-RNYLIPKGTTILTSLT 370

Query: 290 SIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRL 349
           S+  D   +  PE F P  FLDE  +  K   FMPF  G R C+G   A ME+ + L  +
Sbjct: 371 SVLHDNKEFPNPEMFDPRHFLDEGGNFKKSNYFMPFSAGKRICVGEGLARMELFLFLTFI 430

Query: 350 MLNFKV 355
           + NF +
Sbjct: 431 LQNFNL 436


>AY796203-1|AAV41877.1|  490|Homo sapiens cytochrome P450, family 2,
           subfamily C, polypeptide 19 protein.
          Length = 490

 Score = 66.5 bits (155), Expect = 2e-10
 Identities = 51/186 (27%), Positives = 82/186 (44%), Gaps = 8/186 (4%)

Query: 171 TEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVY 230
           +E+T   L         AG ETT  TL   +  L   P +   + EE++       +   
Sbjct: 280 SEFTIENLVITAADLLGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVVGRNRSPCM 339

Query: 231 ENIGELKYLDCVLNETMRKWSAAIFVDRICTK-PYVLPPPREGGKPCQLKPGEVIYNTVN 289
           ++ G + Y D V++E  R      ++D I T  P+ +    +  +   +  G  I  ++ 
Sbjct: 340 QDRGHMPYTDAVVHEVQR------YIDLIPTSLPHAVTCDVKF-RNYLIPKGTTILTSLT 392

Query: 290 SIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRL 349
           S+  D   +  PE F P  FLDE  +  K   FMPF  G R C+G   A ME+ + L  +
Sbjct: 393 SVLHDNKEFPNPEMFDPRHFLDEGGNFKKSNYFMPFSAGKRICVGEGLARMELFLFLTFI 452

Query: 350 MLNFKV 355
           + NF +
Sbjct: 453 LQNFNL 458


>AL583836-2|CAH74068.1|  490|Homo sapiens cytochrome P450, family 2,
           subfamily C, polypeptide 19 protein.
          Length = 490

 Score = 66.5 bits (155), Expect = 2e-10
 Identities = 51/186 (27%), Positives = 82/186 (44%), Gaps = 8/186 (4%)

Query: 171 TEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVY 230
           +E+T   L         AG ETT  TL   +  L   P +   + EE++       +   
Sbjct: 280 SEFTIENLVITAADLLGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVVGRNRSPCM 339

Query: 231 ENIGELKYLDCVLNETMRKWSAAIFVDRICTK-PYVLPPPREGGKPCQLKPGEVIYNTVN 289
           ++ G + Y D V++E  R      ++D I T  P+ +    +  +   +  G  I  ++ 
Sbjct: 340 QDRGHMPYTDAVVHEVQR------YIDLIPTSLPHAVTCDVKF-RNYLIPKGTTILTSLT 392

Query: 290 SIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRL 349
           S+  D   +  PE F P  FLDE  +  K   FMPF  G R C+G   A ME+ + L  +
Sbjct: 393 SVLHDNKEFPNPEMFDPRHFLDEGGNFKKSNYFMPFSAGKRICVGEGLARMELFLFLTFI 452

Query: 350 MLNFKV 355
           + NF +
Sbjct: 453 LQNFNL 458


>AL133513-2|CAH73444.1|  490|Homo sapiens cytochrome P450, family 2,
           subfamily C, polypeptide 19 protein.
          Length = 490

 Score = 66.5 bits (155), Expect = 2e-10
 Identities = 51/186 (27%), Positives = 82/186 (44%), Gaps = 8/186 (4%)

Query: 171 TEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVY 230
           +E+T   L         AG ETT  TL   +  L   P +   + EE++       +   
Sbjct: 280 SEFTIENLVITAADLLGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVVGRNRSPCM 339

Query: 231 ENIGELKYLDCVLNETMRKWSAAIFVDRICTK-PYVLPPPREGGKPCQLKPGEVIYNTVN 289
           ++ G + Y D V++E  R      ++D I T  P+ +    +  +   +  G  I  ++ 
Sbjct: 340 QDRGHMPYTDAVVHEVQR------YIDLIPTSLPHAVTCDVKF-RNYLIPKGTTILTSLT 392

Query: 290 SIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRL 349
           S+  D   +  PE F P  FLDE  +  K   FMPF  G R C+G   A ME+ + L  +
Sbjct: 393 SVLHDNKEFPNPEMFDPRHFLDEGGNFKKSNYFMPFSAGKRICVGEGLARMELFLFLTFI 452

Query: 350 MLNFKV 355
           + NF +
Sbjct: 453 LQNFNL 458


>U22028-1|AAB40519.1|  494|Homo sapiens cytochrome P450 protein.
          Length = 494

 Score = 66.1 bits (154), Expect = 2e-10
 Identities = 54/205 (26%), Positives = 86/205 (41%), Gaps = 9/205 (4%)

Query: 170 STEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLV 229
           +TE+    L       F AG ET   TL      L   P ++  ++EE+           
Sbjct: 283 NTEFYLKNLVMTTLNLFFAGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPK 342

Query: 230 YENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVN 289
           +E+  ++ Y + V++E  R      F D +              +   L  G  ++  + 
Sbjct: 343 FEDRAKMPYTEAVIHEIQR------FGDMLPMGLAHRVNKDTKFRDFFLPKGTEVFPMLG 396

Query: 290 SIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRL 349
           S   DP ++  P+   P+ FLDE     K   F+PF +G RYC G   A ME+ +    +
Sbjct: 397 SELRDPRFFSNPQDCSPQHFLDEKGQFKKSDAFVPFSIGKRYCFGEGLARMELFLFFTTI 456

Query: 350 MLNFKVLKCAKTLDPIKMSP--VGF 372
           M NF+  K  ++   I +SP  VGF
Sbjct: 457 MQNFR-FKSPQSPKDIDVSPKHVGF 480


>M61854-1|AAB59426.1|  490|Homo sapiens cytochrome protein.
          Length = 490

 Score = 66.1 bits (154), Expect = 2e-10
 Identities = 51/186 (27%), Positives = 82/186 (44%), Gaps = 8/186 (4%)

Query: 171 TEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVY 230
           +E+T   L         AG ETT  TL   +  L   P +   + EE++       +   
Sbjct: 280 SEFTIENLVITAADLLGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCM 339

Query: 231 ENIGELKYLDCVLNETMRKWSAAIFVDRICTK-PYVLPPPREGGKPCQLKPGEVIYNTVN 289
           ++ G + Y D V++E  R      ++D I T  P+ +    +  +   +  G  I  ++ 
Sbjct: 340 QDRGHMPYTDAVVHEVQR------YIDLIPTSLPHAVTCDVKF-RNYLIPKGTTILTSLT 392

Query: 290 SIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRL 349
           S+  D   +  PE F P  FLDE  +  K   FMPF  G R C+G   A ME+ + L  +
Sbjct: 393 SVLHDNKEFPNPEMFDPRHFLDEGGNFKKSNYFMPFSAGKRICVGEGLARMELFLFLTFI 452

Query: 350 MLNFKV 355
           + NF +
Sbjct: 453 LQNFNL 458


>L39102-1|AAL31348.1|  217|Homo sapiens S-mephenytoin 4-hydroxylase
           protein.
          Length = 217

 Score = 66.1 bits (154), Expect = 2e-10
 Identities = 51/186 (27%), Positives = 82/186 (44%), Gaps = 8/186 (4%)

Query: 171 TEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVY 230
           +E+T   L         AG ETT  TL   +  L   P +   + EE++       +   
Sbjct: 7   SEFTIENLVITAADLLGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCM 66

Query: 231 ENIGELKYLDCVLNETMRKWSAAIFVDRICTK-PYVLPPPREGGKPCQLKPGEVIYNTVN 289
           ++ G + Y D V++E  R      ++D I T  P+ +    +  +   +  G  I  ++ 
Sbjct: 67  QDRGHMPYTDAVVHEVQR------YIDLIPTSLPHAVTCDVKF-RNYLIPKGTTILTSLT 119

Query: 290 SIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRL 349
           S+  D   +  PE F P  FLDE  +  K   FMPF  G R C+G   A ME+ + L  +
Sbjct: 120 SVLHDNKEFPNPEMFDPRHFLDEGGNFKKSNYFMPFSAGKRICVGEGLARMELFLFLTFI 179

Query: 350 MLNFKV 355
           + NF +
Sbjct: 180 LQNFNL 185


>AY288916-1|AAP31972.1|  508|Homo sapiens cytochrome P450, family
           27, subfamily B, polypeptide 1 protein.
          Length = 508

 Score = 66.1 bits (154), Expect = 2e-10
 Identities = 47/173 (27%), Positives = 83/173 (47%), Gaps = 14/173 (8%)

Query: 187 VAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYEN---IGELKYLDCVL 243
           +AG +T  NTL   ++EL+  P +Q  L+ E+ A   + G+  Y +   + +L  L  V+
Sbjct: 316 LAGVDTVSNTLSWALYELSRHPEVQTALHSEITAAL-SPGSSAYPSATVLSQLPLLKAVV 374

Query: 244 NETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVN-SIHMDPIYYEEPE 302
            E +R +       R+        P ++      + P   +    + +   DP  + EP 
Sbjct: 375 KEVLRLYPVVPGNSRV--------PDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPN 426

Query: 303 KFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKV 355
            F P R+L E      PF  +PFG G R C+G R A +E+++ L +++ +F+V
Sbjct: 427 SFRPARWLGEGPTP-HPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEV 478


>AF256213-1|AAG00416.1|  508|Homo sapiens 25- hydroxyvitamin
           D-1-alpha-hydroxylase protein.
          Length = 508

 Score = 66.1 bits (154), Expect = 2e-10
 Identities = 47/173 (27%), Positives = 83/173 (47%), Gaps = 14/173 (8%)

Query: 187 VAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYEN---IGELKYLDCVL 243
           +AG +T  NTL   ++EL+  P +Q  L+ E+ A   + G+  Y +   + +L  L  V+
Sbjct: 316 LAGVDTVSNTLSWALYELSRHPEVQTALHSEITAAL-SPGSSAYPSATVLSQLPLLKAVV 374

Query: 244 NETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVN-SIHMDPIYYEEPE 302
            E +R +       R+        P ++      + P   +    + +   DP  + EP 
Sbjct: 375 KEVLRLYPVVPGNSRV--------PDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPN 426

Query: 303 KFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKV 355
            F P R+L E      PF  +PFG G R C+G R A +E+++ L +++ +F+V
Sbjct: 427 SFRPARWLGEGPTP-HPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEV 478


>AF246895-1|AAF64299.1|  508|Homo sapiens 25-hydroxyvitamin
           D-1-alpha-hydroxylase protein.
          Length = 508

 Score = 66.1 bits (154), Expect = 2e-10
 Identities = 47/173 (27%), Positives = 83/173 (47%), Gaps = 14/173 (8%)

Query: 187 VAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYEN---IGELKYLDCVL 243
           +AG +T  NTL   ++EL+  P +Q  L+ E+ A   + G+  Y +   + +L  L  V+
Sbjct: 316 LAGVDTVSNTLSWALYELSRHPEVQTALHSEITAAL-SPGSSAYPSATVLSQLPLLKAVV 374

Query: 244 NETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVN-SIHMDPIYYEEPE 302
            E +R +       R+        P ++      + P   +    + +   DP  + EP 
Sbjct: 375 KEVLRLYPVVPGNSRV--------PDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPN 426

Query: 303 KFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKV 355
            F P R+L E      PF  +PFG G R C+G R A +E+++ L +++ +F+V
Sbjct: 427 SFRPARWLGEGPTP-HPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEV 478


>AF027152-1|AAC51854.1|  508|Homo sapiens P450 25-hydroxyvitamin D-1
           alpha hydroxylase protein.
          Length = 508

 Score = 66.1 bits (154), Expect = 2e-10
 Identities = 47/173 (27%), Positives = 83/173 (47%), Gaps = 14/173 (8%)

Query: 187 VAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYEN---IGELKYLDCVL 243
           +AG +T  NTL   ++EL+  P +Q  L+ E+ A   + G+  Y +   + +L  L  V+
Sbjct: 316 LAGVDTVSNTLSWALYELSRHPEVQTALHSEITAAL-SPGSSAYPSATVLSQLPLLKAVV 374

Query: 244 NETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVN-SIHMDPIYYEEPE 302
            E +R +       R+        P ++      + P   +    + +   DP  + EP 
Sbjct: 375 KEVLRLYPVVPGNSRV--------PDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPN 426

Query: 303 KFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKV 355
            F P R+L E      PF  +PFG G R C+G R A +E+++ L +++ +F+V
Sbjct: 427 SFRPARWLGEGPTP-HPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEV 478


>AF020192-1|AAC51853.1|  508|Homo sapiens 25-hydroxyvitamin
           D-1-alpha-hydroxylase protein.
          Length = 508

 Score = 66.1 bits (154), Expect = 2e-10
 Identities = 47/173 (27%), Positives = 83/173 (47%), Gaps = 14/173 (8%)

Query: 187 VAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYEN---IGELKYLDCVL 243
           +AG +T  NTL   ++EL+  P +Q  L+ E+ A   + G+  Y +   + +L  L  V+
Sbjct: 316 LAGVDTVSNTLSWALYELSRHPEVQTALHSEITAAL-SPGSSAYPSATVLSQLPLLKAVV 374

Query: 244 NETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVN-SIHMDPIYYEEPE 302
            E +R +       R+        P ++      + P   +    + +   DP  + EP 
Sbjct: 375 KEVLRLYPVVPGNSRV--------PDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPN 426

Query: 303 KFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKV 355
            F P R+L E      PF  +PFG G R C+G R A +E+++ L +++ +F+V
Sbjct: 427 SFRPARWLGEGPTP-HPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEV 478


>AB006987-1|BAA23418.1|  508|Homo sapiens 25-hydroxyvitamin D3
           1-alpha-hydroxylase protein.
          Length = 508

 Score = 66.1 bits (154), Expect = 2e-10
 Identities = 47/173 (27%), Positives = 83/173 (47%), Gaps = 14/173 (8%)

Query: 187 VAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYEN---IGELKYLDCVL 243
           +AG +T  NTL   ++EL+  P +Q  L+ E+ A   + G+  Y +   + +L  L  V+
Sbjct: 316 LAGVDTVSNTLSWALYELSRHPEVQTALHSEITAAL-SPGSSAYPSATVLSQLPLLKAVV 374

Query: 244 NETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVN-SIHMDPIYYEEPE 302
            E +R +       R+        P ++      + P   +    + +   DP  + EP 
Sbjct: 375 KEVLRLYPVVPGNSRV--------PDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPN 426

Query: 303 KFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKV 355
            F P R+L E      PF  +PFG G R C+G R A +E+++ L +++ +F+V
Sbjct: 427 SFRPARWLGEGPTP-HPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEV 478


>AB005990-1|BAA22657.1|  508|Homo sapiens 25-hydroxyvitamin D3
           1alpha-hydroxylase protein.
          Length = 508

 Score = 66.1 bits (154), Expect = 2e-10
 Identities = 47/173 (27%), Positives = 83/173 (47%), Gaps = 14/173 (8%)

Query: 187 VAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYEN---IGELKYLDCVL 243
           +AG +T  NTL   ++EL+  P +Q  L+ E+ A   + G+  Y +   + +L  L  V+
Sbjct: 316 LAGVDTVSNTLSWALYELSRHPEVQTALHSEITAAL-SPGSSAYPSATVLSQLPLLKAVV 374

Query: 244 NETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVN-SIHMDPIYYEEPE 302
            E +R +       R+        P ++      + P   +    + +   DP  + EP 
Sbjct: 375 KEVLRLYPVVPGNSRV--------PDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPN 426

Query: 303 KFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKV 355
            F P R+L E      PF  +PFG G R C+G R A +E+++ L +++ +F+V
Sbjct: 427 SFRPARWLGEGPTP-HPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEV 478


>AB005989-1|BAA22656.1|  508|Homo sapiens 25-hydroxyvitamin D3
           1alpha-hydroxylase protein.
          Length = 508

 Score = 66.1 bits (154), Expect = 2e-10
 Identities = 47/173 (27%), Positives = 83/173 (47%), Gaps = 14/173 (8%)

Query: 187 VAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYEN---IGELKYLDCVL 243
           +AG +T  NTL   ++EL+  P +Q  L+ E+ A   + G+  Y +   + +L  L  V+
Sbjct: 316 LAGVDTVSNTLSWALYELSRHPEVQTALHSEITAAL-SPGSSAYPSATVLSQLPLLKAVV 374

Query: 244 NETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVN-SIHMDPIYYEEPE 302
            E +R +       R+        P ++      + P   +    + +   DP  + EP 
Sbjct: 375 KEVLRLYPVVPGNSRV--------PDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPN 426

Query: 303 KFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKV 355
            F P R+L E      PF  +PFG G R C+G R A +E+++ L +++ +F+V
Sbjct: 427 SFRPARWLGEGPTP-HPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEV 478


>AB005038-1|BAA23416.1|  508|Homo sapiens 25-hydroxyvitamin D3
           1-alpha-hydroxylase protein.
          Length = 508

 Score = 66.1 bits (154), Expect = 2e-10
 Identities = 47/173 (27%), Positives = 83/173 (47%), Gaps = 14/173 (8%)

Query: 187 VAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYEN---IGELKYLDCVL 243
           +AG +T  NTL   ++EL+  P +Q  L+ E+ A   + G+  Y +   + +L  L  V+
Sbjct: 316 LAGVDTVSNTLSWALYELSRHPEVQTALHSEITAAL-SPGSSAYPSATVLSQLPLLKAVV 374

Query: 244 NETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVN-SIHMDPIYYEEPE 302
            E +R +       R+        P ++      + P   +    + +   DP  + EP 
Sbjct: 375 KEVLRLYPVVPGNSRV--------PDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPN 426

Query: 303 KFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKV 355
            F P R+L E      PF  +PFG G R C+G R A +E+++ L +++ +F+V
Sbjct: 427 SFRPARWLGEGPTP-HPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEV 478


>BC025761-1|AAH25761.2|  490|Homo sapiens cytochrome P450, family 2,
           subfamily W, polypeptide 1 protein.
          Length = 490

 Score = 65.7 bits (153), Expect = 3e-10
 Identities = 53/184 (28%), Positives = 78/184 (42%), Gaps = 7/184 (3%)

Query: 173 WTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYEN 232
           + E    A      +AG ETT  TL      +   P +Q  + EEL            E+
Sbjct: 281 FAEANAVACTLDMVMAGTETTSATLQWAALLMGRHPDVQGRVQEELDRVLGPGRTPRLED 340

Query: 233 IGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIH 292
              L Y   VL+E  R  +    V R CT        + GG    L  G  +   + S+ 
Sbjct: 341 QQALPYTSAVLHEVQRFITLLPHVPR-CTAA----DTQLGG--FLLPKGTPVIPLLTSVL 393

Query: 293 MDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLN 352
           +D   ++ P +F P  FLD N H +K   F+PF  G R C+G R A  E+ +L   L+  
Sbjct: 394 LDETQWQTPGQFNPGHFLDANGHFVKREAFLPFSAGRRVCVGERLARTELFLLFAGLLQR 453

Query: 353 FKVL 356
           +++L
Sbjct: 454 YRLL 457


>AM183950-1|CAJ75804.1|  494|Homo sapiens steroid 21-hydroxylase,
           CYP21 protein.
          Length = 494

 Score = 65.7 bits (153), Expect = 3e-10
 Identities = 52/186 (27%), Positives = 79/186 (42%), Gaps = 13/186 (6%)

Query: 187 VAGFETTGNTLINCIHELALSPHIQDILYEELK---AFKETKGNLVYENIGELKYLDCVL 243
           + G ETT NTL   +  L   P IQ  L EEL        +   + Y++   L  L+  +
Sbjct: 290 IGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATI 349

Query: 244 NETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHMDPIYYEEPEK 303
            E +R           CT     P    G     +  G VI   +   H+D   +E P +
Sbjct: 350 AEVLRLRPVVPLALPHCT---TRPSSISG---YDIPEGTVIIPNLQGAHLDETVWERPHE 403

Query: 304 FIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVLKCAKTLD 363
           F P+RFL+  K+       + FG G R C+G   A +E+ ++L RL+  F +L     L 
Sbjct: 404 FWPDRFLEPGKNS----RALAFGCGARVCLGEPLARLELFVVLTRLLQAFTLLPSGDALP 459

Query: 364 PIKMSP 369
            ++  P
Sbjct: 460 SLQPLP 465


>AJ563379-2|CAD91649.1|   84|Homo sapiens cytochrome P450 protein.
          Length = 84

 Score = 65.7 bits (153), Expect = 3e-10
 Identities = 28/60 (46%), Positives = 37/60 (61%)

Query: 312 ENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVLKCAKTLDPIKMSPVG 371
           + K  I P+ + PFG GPR CIG RFALM MK+ L R++ NF    C +T  P+K+   G
Sbjct: 3   KKKDSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLDTQG 62


>M61856-1|AAB59356.1|  490|Homo sapiens cytochrome protein.
          Length = 490

 Score = 65.3 bits (152), Expect = 3e-10
 Identities = 54/201 (26%), Positives = 91/201 (45%), Gaps = 9/201 (4%)

Query: 171 TEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVY 230
           +E+T   L A +   F AG ETT  TL   +  L   P +   + EE++       +   
Sbjct: 280 SEFTVESLIATVTDMFGAGTETTSTTLRYGLLLLLKYPEVTAKVQEEIECVVGRNRSPCM 339

Query: 231 ENIGELKYLDCVLNETMRKWSAAIFVDRICTK-PYVLPPPREGGKPCQLKPGEVIYNTVN 289
           ++   + Y D V++E  R      ++D + T  P+ +    +  K   +  G  I  ++ 
Sbjct: 340 QDRSHMPYTDAVVHEIQR------YIDLLPTNLPHAVTCDVKF-KNYLIPKGTTIITSLT 392

Query: 290 SIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRL 349
           S+  +   +  PE F P  FLD++ +  K   FMPF  G R C+G   A ME+ + L  +
Sbjct: 393 SVLHNDKEFPNPEMFDPGHFLDKSGNFKKSDYFMPFSAGKRMCMGEGLARMELFLFLTTI 452

Query: 350 MLNFKVLKCAKTLDPIKMSPV 370
           + NF  LK       I ++P+
Sbjct: 453 LQNFN-LKSQVDPKDIDITPI 472


>BX538127-1|CAD98029.1|  310|Homo sapiens hypothetical protein
           protein.
          Length = 310

 Score = 65.3 bits (152), Expect = 3e-10
 Identities = 54/201 (26%), Positives = 91/201 (45%), Gaps = 9/201 (4%)

Query: 171 TEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVY 230
           +E+T   L A +   F AG ETT  TL   +  L   P +   + EE++       +   
Sbjct: 100 SEFTVESLIATVTDMFGAGTETTSTTLRYGLLLLLKYPEVTAKVQEEIECVVGRNRSPCM 159

Query: 231 ENIGELKYLDCVLNETMRKWSAAIFVDRICTK-PYVLPPPREGGKPCQLKPGEVIYNTVN 289
           ++   + Y D V++E  R      ++D + T  P+ +    +  K   +  G  I  ++ 
Sbjct: 160 QDRSHMPYTDAVVHEIQR------YIDLLPTNLPHAVTCDVKF-KNYLIPKGTTIITSLT 212

Query: 290 SIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRL 349
           S+  +   +  PE F P  FLD++ +  K   FMPF  G R C+G   A ME+ + L  +
Sbjct: 213 SVLHNDKEFPNPEMFDPGHFLDKSGNFKKSDYFMPFSAGKRMCMGEGLARMELFLFLTTI 272

Query: 350 MLNFKVLKCAKTLDPIKMSPV 370
           + NF  LK       I ++P+
Sbjct: 273 LQNFN-LKSQVDPKDIDITPI 292


>BC096260-1|AAH96260.1|  431|Homo sapiens CYP2C18 protein protein.
          Length = 431

 Score = 65.3 bits (152), Expect = 3e-10
 Identities = 54/201 (26%), Positives = 91/201 (45%), Gaps = 9/201 (4%)

Query: 171 TEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVY 230
           +E+T   L A +   F AG ETT  TL   +  L   P +   + EE++       +   
Sbjct: 221 SEFTVESLIATVTDMFGAGTETTSTTLRYGLLLLLKYPEVTAKVQEEIECVVGRNRSPCM 280

Query: 231 ENIGELKYLDCVLNETMRKWSAAIFVDRICTK-PYVLPPPREGGKPCQLKPGEVIYNTVN 289
           ++   + Y D V++E  R      ++D + T  P+ +    +  K   +  G  I  ++ 
Sbjct: 281 QDRSHMPYTDAVVHEIQR------YIDLLPTNLPHAVTCDVKF-KNYLIPKGTTIITSLT 333

Query: 290 SIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRL 349
           S+  +   +  PE F P  FLD++ +  K   FMPF  G R C+G   A ME+ + L  +
Sbjct: 334 SVLHNDKEFPNPEMFDPGHFLDKSGNFKKSDYFMPFSAGKRMCMGEGLARMELFLFLTTI 393

Query: 350 MLNFKVLKCAKTLDPIKMSPV 370
           + NF  LK       I ++P+
Sbjct: 394 LQNFN-LKSQVDPKDIDITPI 413


>BC096258-1|AAH96258.1|  490|Homo sapiens cytochrome P450, family 2,
           subfamily C, polypeptide 18 protein.
          Length = 490

 Score = 65.3 bits (152), Expect = 3e-10
 Identities = 54/201 (26%), Positives = 91/201 (45%), Gaps = 9/201 (4%)

Query: 171 TEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVY 230
           +E+T   L A +   F AG ETT  TL   +  L   P +   + EE++       +   
Sbjct: 280 SEFTVESLIATVTDMFGAGTETTSTTLRYGLLLLLKYPEVTAKVQEEIECVVGRNRSPCM 339

Query: 231 ENIGELKYLDCVLNETMRKWSAAIFVDRICTK-PYVLPPPREGGKPCQLKPGEVIYNTVN 289
           ++   + Y D V++E  R      ++D + T  P+ +    +  K   +  G  I  ++ 
Sbjct: 340 QDRSHMPYTDAVVHEIQR------YIDLLPTNLPHAVTCDVKF-KNYLIPKGTTIITSLT 392

Query: 290 SIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRL 349
           S+  +   +  PE F P  FLD++ +  K   FMPF  G R C+G   A ME+ + L  +
Sbjct: 393 SVLHNDKEFPNPEMFDPGHFLDKSGNFKKSDYFMPFSAGKRMCMGEGLARMELFLFLTTI 452

Query: 350 MLNFKVLKCAKTLDPIKMSPV 370
           + NF  LK       I ++P+
Sbjct: 453 LQNFN-LKSQVDPKDIDITPI 472


>BC096257-1|AAH96257.1|  490|Homo sapiens cytochrome P450, family 2,
           subfamily C, polypeptide 18 protein.
          Length = 490

 Score = 65.3 bits (152), Expect = 3e-10
 Identities = 54/201 (26%), Positives = 91/201 (45%), Gaps = 9/201 (4%)

Query: 171 TEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVY 230
           +E+T   L A +   F AG ETT  TL   +  L   P +   + EE++       +   
Sbjct: 280 SEFTVESLIATVTDMFGAGTETTSTTLRYGLLLLLKYPEVTAKVQEEIECVVGRNRSPCM 339

Query: 231 ENIGELKYLDCVLNETMRKWSAAIFVDRICTK-PYVLPPPREGGKPCQLKPGEVIYNTVN 289
           ++   + Y D V++E  R      ++D + T  P+ +    +  K   +  G  I  ++ 
Sbjct: 340 QDRSHMPYTDAVVHEIQR------YIDLLPTNLPHAVTCDVKF-KNYLIPKGTTIITSLT 392

Query: 290 SIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRL 349
           S+  +   +  PE F P  FLD++ +  K   FMPF  G R C+G   A ME+ + L  +
Sbjct: 393 SVLHNDKEFPNPEMFDPGHFLDKSGNFKKSDYFMPFSAGKRMCMGEGLARMELFLFLTTI 452

Query: 350 MLNFKVLKCAKTLDPIKMSPV 370
           + NF  LK       I ++P+
Sbjct: 453 LQNFN-LKSQVDPKDIDITPI 472


>BC069666-1|AAH69666.1|  490|Homo sapiens cytochrome P450, family 2,
           subfamily C, polypeptide 18 protein.
          Length = 490

 Score = 65.3 bits (152), Expect = 3e-10
 Identities = 54/201 (26%), Positives = 91/201 (45%), Gaps = 9/201 (4%)

Query: 171 TEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVY 230
           +E+T   L A +   F AG ETT  TL   +  L   P +   + EE++       +   
Sbjct: 280 SEFTVESLIATVTDMFGAGTETTSTTLRYGLLLLLKYPEVTAKVQEEIECVVGRNRSPCM 339

Query: 231 ENIGELKYLDCVLNETMRKWSAAIFVDRICTK-PYVLPPPREGGKPCQLKPGEVIYNTVN 289
           ++   + Y D V++E  R      ++D + T  P+ +    +  K   +  G  I  ++ 
Sbjct: 340 QDRSHMPYTDAVVHEIQR------YIDLLPTNLPHAVTCDVKF-KNYLIPKGTTIITSLT 392

Query: 290 SIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRL 349
           S+  +   +  PE F P  FLD++ +  K   FMPF  G R C+G   A ME+ + L  +
Sbjct: 393 SVLHNDKEFPNPEMFDPGHFLDKSGNFKKSDYFMPFSAGKRMCMGEGLARMELFLFLTTI 452

Query: 350 MLNFKVLKCAKTLDPIKMSPV 370
           + NF  LK       I ++P+
Sbjct: 453 LQNFN-LKSQVDPKDIDITPI 472


>AL583836-1|CAH74067.1|  490|Homo sapiens cytochrome P450, family 2,
           subfamily C, polypeptide 18 protein.
          Length = 490

 Score = 65.3 bits (152), Expect = 3e-10
 Identities = 54/201 (26%), Positives = 91/201 (45%), Gaps = 9/201 (4%)

Query: 171 TEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVY 230
           +E+T   L A +   F AG ETT  TL   +  L   P +   + EE++       +   
Sbjct: 280 SEFTVESLIATVTDMFGAGTETTSTTLRYGLLLLLKYPEVTAKVQEEIECVVGRNRSPCM 339

Query: 231 ENIGELKYLDCVLNETMRKWSAAIFVDRICTK-PYVLPPPREGGKPCQLKPGEVIYNTVN 289
           ++   + Y D V++E  R      ++D + T  P+ +    +  K   +  G  I  ++ 
Sbjct: 340 QDRSHMPYTDAVVHEIQR------YIDLLPTNLPHAVTCDVKF-KNYLIPKGTTIITSLT 392

Query: 290 SIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRL 349
           S+  +   +  PE F P  FLD++ +  K   FMPF  G R C+G   A ME+ + L  +
Sbjct: 393 SVLHNDKEFPNPEMFDPGHFLDKSGNFKKSDYFMPFSAGKRMCMGEGLARMELFLFLTTI 452

Query: 350 MLNFKVLKCAKTLDPIKMSPV 370
           + NF  LK       I ++P+
Sbjct: 453 LQNFN-LKSQVDPKDIDITPI 472


>AK223510-1|BAD97230.1|  490|Homo sapiens cytochrome P450, family 2,
           subfamily C, polypeptide 18 variant protein.
          Length = 490

 Score = 65.3 bits (152), Expect = 3e-10
 Identities = 54/201 (26%), Positives = 91/201 (45%), Gaps = 9/201 (4%)

Query: 171 TEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVY 230
           +E+T   L A +   F AG ETT  TL   +  L   P +   + EE++       +   
Sbjct: 280 SEFTVESLIATVTDMFGAGTETTSTTLRYGLLLLLKYPEVTAKVQEEIECVVGRNRSPCM 339

Query: 231 ENIGELKYLDCVLNETMRKWSAAIFVDRICTK-PYVLPPPREGGKPCQLKPGEVIYNTVN 289
           ++   + Y D V++E  R      ++D + T  P+ +    +  K   +  G  I  ++ 
Sbjct: 340 QDRSHMPYTDAVVHEIQR------YIDLLPTNLPHAVTCDVKF-KNYLIPKGTTIITSLT 392

Query: 290 SIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRL 349
           S+  +   +  PE F P  FLD++ +  K   FMPF  G R C+G   A ME+ + L  +
Sbjct: 393 SVLHNDKEFPNPEMFDPGHFLDKSGNFKKSDYFMPFSAGKRMCMGEGLARMELFLFLTTI 452

Query: 350 MLNFKVLKCAKTLDPIKMSPV 370
           + NF  LK       I ++P+
Sbjct: 453 LQNFN-LKSKVDPKDIDITPI 472


>U37143-1|AAC50370.2|  502|Homo sapiens cytochrome P450
           monooxygenase CYP2J2 protein.
          Length = 502

 Score = 64.9 bits (151), Expect = 5e-10
 Identities = 51/185 (27%), Positives = 78/185 (42%), Gaps = 9/185 (4%)

Query: 170 STEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLV 229
           ++ + E  L       F AG ETT  TL   +  +AL P IQ+ +  E+           
Sbjct: 293 TSSFHEENLICSTLDLFFAGTETTSTTLRWALLYMALYPEIQEKVQAEIDRVIGQGQQPS 352

Query: 230 YENIGELKYLDCVLNETMRKWSAA-IFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTV 288
                 + Y + V++E  R  +   + V R  T    L           L  G +I   +
Sbjct: 353 TAARESMPYTNAVIHEVQRMGNIIPLNVPREVTVDTTLAG-------YHLPKGTMILTNL 405

Query: 289 NSIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFR 348
            ++H DP  +  P+ F P+ FL+  + K K   FMPF +G R C+G + A  E+ I    
Sbjct: 406 TALHRDPTEWATPDTFNPDHFLENGQFK-KREAFMPFSIGKRACLGEQLARTELFIFFTS 464

Query: 349 LMLNF 353
           LM  F
Sbjct: 465 LMQKF 469


>S46963-1|AAB23864.2|  477|Homo sapiens cytochrome P-450 protein.
          Length = 477

 Score = 64.9 bits (151), Expect = 5e-10
 Identities = 55/196 (28%), Positives = 86/196 (43%), Gaps = 10/196 (5%)

Query: 171 TEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVY 230
           +E+T   L       F AG ETT  TL   +  L   P +   + EE++       +   
Sbjct: 267 SEFTIESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCM 326

Query: 231 ENIGELKYLDCVLNETMRKWSAAIFVDRICTK-PYVLPPPREGGKPCQLKPGEVIYNTVN 289
           ++   + Y D V++E  R      ++D + T  P+ +    +  +   +  G  I  ++ 
Sbjct: 327 QDRSHMPYTDAVVHEVQR------YIDLLPTSLPHAVTCDIKF-RNYLIPKGTTILISLT 379

Query: 290 SIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRL 349
           S+  D   +  PE F P  FLDE  +  K   FMPF  G R C+G   A ME+ + L  +
Sbjct: 380 SVLHDNKEFPNPEMFDPHHFLDEGGNFKKSKYFMPFSAGKRICVGEALAGMELFLFLTSI 439

Query: 350 MLNF--KVLKCAKTLD 363
           + NF  K L   K LD
Sbjct: 440 LQNFNLKSLVDPKNLD 455


>L16876-1|AAA02630.1|  490|Homo sapiens cytochrome P-4502C18
           protein.
          Length = 490

 Score = 64.9 bits (151), Expect = 5e-10
 Identities = 54/201 (26%), Positives = 91/201 (45%), Gaps = 9/201 (4%)

Query: 171 TEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVY 230
           +E+T   L A +   F AG ETT  TL   +  L   P +   + EE++       +   
Sbjct: 280 SEFTVESLIATVTDMFGAGTETTSTTLRYGLLLLLKYPEVTAKVQEEIECVVGRNRSPCM 339

Query: 231 ENIGELKYLDCVLNETMRKWSAAIFVDRICTK-PYVLPPPREGGKPCQLKPGEVIYNTVN 289
           ++   + Y D V++E  R      ++D + T  P+ +    +  K   +  G  I  ++ 
Sbjct: 340 QDRSHMPYTDAVVHEIQR------YIDLLPTNLPHAVTCDVKF-KNYLIPKGMTIITSLT 392

Query: 290 SIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRL 349
           S+  +   +  PE F P  FLD++ +  K   FMPF  G R C+G   A ME+ + L  +
Sbjct: 393 SVLHNDKEFPNPEMFDPGHFLDKSGNFKKSDYFMPFSAGKRMCMGEGLARMELFLFLTTI 452

Query: 350 MLNFKVLKCAKTLDPIKMSPV 370
           + NF  LK       I ++P+
Sbjct: 453 LQNFN-LKSQVDPKDIDITPI 472


>D00173-1|BAA00123.1|  487|Homo sapiens cytochrome P-450 protein.
          Length = 487

 Score = 64.9 bits (151), Expect = 5e-10
 Identities = 55/196 (28%), Positives = 86/196 (43%), Gaps = 10/196 (5%)

Query: 171 TEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVY 230
           +E+T   L       F AG ETT  TL   +  L   P +   + EE++       +   
Sbjct: 277 SEFTIESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCM 336

Query: 231 ENIGELKYLDCVLNETMRKWSAAIFVDRICTK-PYVLPPPREGGKPCQLKPGEVIYNTVN 289
           ++   + Y D V++E  R      ++D + T  P+ +    +  +   +  G  I  ++ 
Sbjct: 337 QDRSHMPYTDAVVHEVQR------YIDLLPTSLPHAVTCDIKF-RNYLIPKGTTILISLT 389

Query: 290 SIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRL 349
           S+  D   +  PE F P  FLDE  +  K   FMPF  G R C+G   A ME+ + L  +
Sbjct: 390 SVLHDNKEFPNPEMFDPHHFLDEGGNFKKSKYFMPFSAGKRICVGEALAGMELFLFLTSI 449

Query: 350 MLNF--KVLKCAKTLD 363
           + NF  K L   K LD
Sbjct: 450 LQNFNLKSLVDPKNLD 465


>BC125054-1|AAI25055.1|  490|Homo sapiens cytochrome P450, family 2,
           subfamily C, polypeptide 9 protein.
          Length = 490

 Score = 64.9 bits (151), Expect = 5e-10
 Identities = 55/196 (28%), Positives = 86/196 (43%), Gaps = 10/196 (5%)

Query: 171 TEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVY 230
           +E+T   L       F AG ETT  TL   +  L   P +   + EE++       +   
Sbjct: 280 SEFTIESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCM 339

Query: 231 ENIGELKYLDCVLNETMRKWSAAIFVDRICTK-PYVLPPPREGGKPCQLKPGEVIYNTVN 289
           ++   + Y D V++E  R      ++D + T  P+ +    +  +   +  G  I  ++ 
Sbjct: 340 QDRSHMPYTDAVVHEVQR------YIDLLPTSLPHAVTCDIKF-RNYLIPKGTTILISLT 392

Query: 290 SIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRL 349
           S+  D   +  PE F P  FLDE  +  K   FMPF  G R C+G   A ME+ + L  +
Sbjct: 393 SVLHDNKEFPNPEMFDPHHFLDEGGNFKKSKYFMPFSAGKRICVGEALAGMELFLFLTSI 452

Query: 350 MLNF--KVLKCAKTLD 363
           + NF  K L   K LD
Sbjct: 453 LQNFNLKSLVDPKNLD 468


>BC032594-1|AAH32594.1|  502|Homo sapiens cytochrome P450, family 2,
           subfamily J, polypeptide 2 protein.
          Length = 502

 Score = 64.9 bits (151), Expect = 5e-10
 Identities = 51/185 (27%), Positives = 78/185 (42%), Gaps = 9/185 (4%)

Query: 170 STEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLV 229
           ++ + E  L       F AG ETT  TL   +  +AL P IQ+ +  E+           
Sbjct: 293 TSSFHEENLICSTLDLFFAGTETTSTTLRWALLYMALYPEIQEKVQAEIDRVIGQGQQPS 352

Query: 230 YENIGELKYLDCVLNETMRKWSAA-IFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTV 288
                 + Y + V++E  R  +   + V R  T    L           L  G +I   +
Sbjct: 353 TAARESMPYTNAVIHEVQRMGNIIPLNVPREVTVDTTLAG-------YHLPKGTMILTNL 405

Query: 289 NSIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFR 348
            ++H DP  +  P+ F P+ FL+  + K K   FMPF +G R C+G + A  E+ I    
Sbjct: 406 TALHRDPTEWATPDTFNPDHFLENGQFK-KREAFMPFSIGKRACLGEQLARTELFIFFTS 464

Query: 349 LMLNF 353
           LM  F
Sbjct: 465 LMQKF 469


>AY702706-1|AAT94065.1|  490|Homo sapiens cytochrome P450, family 2,
           subfamily C, polypeptide 9 protein.
          Length = 490

 Score = 64.9 bits (151), Expect = 5e-10
 Identities = 55/196 (28%), Positives = 86/196 (43%), Gaps = 10/196 (5%)

Query: 171 TEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVY 230
           +E+T   L       F AG ETT  TL   +  L   P +   + EE++       +   
Sbjct: 280 SEFTIESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCM 339

Query: 231 ENIGELKYLDCVLNETMRKWSAAIFVDRICTK-PYVLPPPREGGKPCQLKPGEVIYNTVN 289
           ++   + Y D V++E  R      ++D + T  P+ +    +  +   +  G  I  ++ 
Sbjct: 340 QDRSHMPYTDAVVHEVQR------YIDLLPTSLPHAVTCDIKF-RNYLIPKGTTILISLT 392

Query: 290 SIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRL 349
           S+  D   +  PE F P  FLDE  +  K   FMPF  G R C+G   A ME+ + L  +
Sbjct: 393 SVLHDNKEFPNPEMFDPHHFLDEGGNFKKSKYFMPFSAGKRICVGEALAGMELFLFLTSI 452

Query: 350 MLNF--KVLKCAKTLD 363
           + NF  K L   K LD
Sbjct: 453 LQNFNLKSLVDPKNLD 468


>AY426985-1|AAQ93356.1|  502|Homo sapiens cytochrome P450, family 2,
           subfamily J, polypeptide 2 protein.
          Length = 502

 Score = 64.9 bits (151), Expect = 5e-10
 Identities = 51/185 (27%), Positives = 78/185 (42%), Gaps = 9/185 (4%)

Query: 170 STEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLV 229
           ++ + E  L       F AG ETT  TL   +  +AL P IQ+ +  E+           
Sbjct: 293 TSSFHEENLICSTLDLFFAGTETTSTTLRWALLYMALYPEIQEKVQAEIDRVIGQGQQPS 352

Query: 230 YENIGELKYLDCVLNETMRKWSAA-IFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTV 288
                 + Y + V++E  R  +   + V R  T    L           L  G +I   +
Sbjct: 353 TAARESMPYTNAVIHEVQRMGNIIPLNVPREVTVDTTLAG-------YHLPKGTMILTNL 405

Query: 289 NSIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFR 348
            ++H DP  +  P+ F P+ FL+  + K K   FMPF +G R C+G + A  E+ I    
Sbjct: 406 TALHRDPTEWATPDTFNPDHFLENGQFK-KREAFMPFSIGKRACLGEQLARTELFIFFTS 464

Query: 349 LMLNF 353
           LM  F
Sbjct: 465 LMQKF 469


>AY341248-1|AAP88931.1|  490|Homo sapiens cytochrome P450, family 2,
           subfamily C, polypeptide 9 protein.
          Length = 490

 Score = 64.9 bits (151), Expect = 5e-10
 Identities = 55/196 (28%), Positives = 86/196 (43%), Gaps = 10/196 (5%)

Query: 171 TEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVY 230
           +E+T   L       F AG ETT  TL   +  L   P +   + EE++       +   
Sbjct: 280 SEFTIESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCM 339

Query: 231 ENIGELKYLDCVLNETMRKWSAAIFVDRICTK-PYVLPPPREGGKPCQLKPGEVIYNTVN 289
           ++   + Y D V++E  R      ++D + T  P+ +    +  +   +  G  I  ++ 
Sbjct: 340 QDRSHMPYTDAVVHEVQR------YIDLLPTSLPHAVTCDIKF-RNYLIPKGTTILISLT 392

Query: 290 SIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRL 349
           S+  D   +  PE F P  FLDE  +  K   FMPF  G R C+G   A ME+ + L  +
Sbjct: 393 SVLHDNKEFPNPEMFDPHHFLDEGGNFKKSKYFMPFSAGKRICVGEALAGMELFLFLTSI 452

Query: 350 MLNF--KVLKCAKTLD 363
           + NF  K L   K LD
Sbjct: 453 LQNFNLKSLVDPKNLD 468


>AL359672-1|CAH71303.1|  490|Homo sapiens cytochrome P450, family 2,
           subfamily C, polypeptide 9 protein.
          Length = 490

 Score = 64.9 bits (151), Expect = 5e-10
 Identities = 55/196 (28%), Positives = 86/196 (43%), Gaps = 10/196 (5%)

Query: 171 TEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVY 230
           +E+T   L       F AG ETT  TL   +  L   P +   + EE++       +   
Sbjct: 280 SEFTIESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCM 339

Query: 231 ENIGELKYLDCVLNETMRKWSAAIFVDRICTK-PYVLPPPREGGKPCQLKPGEVIYNTVN 289
           ++   + Y D V++E  R      ++D + T  P+ +    +  +   +  G  I  ++ 
Sbjct: 340 QDRSHMPYTDAVVHEVQR------YIDLLPTSLPHAVTCDIKF-RNYLIPKGTTILISLT 392

Query: 290 SIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRL 349
           S+  D   +  PE F P  FLDE  +  K   FMPF  G R C+G   A ME+ + L  +
Sbjct: 393 SVLHDNKEFPNPEMFDPHHFLDEGGNFKKSKYFMPFSAGKRICVGEALAGMELFLFLTSI 452

Query: 350 MLNF--KVLKCAKTLD 363
           + NF  K L   K LD
Sbjct: 453 LQNFNLKSLVDPKNLD 468


>AF272142-1|AAM44456.1|  502|Homo sapiens cytochrome P450 protein.
          Length = 502

 Score = 64.9 bits (151), Expect = 5e-10
 Identities = 51/185 (27%), Positives = 78/185 (42%), Gaps = 9/185 (4%)

Query: 170 STEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLV 229
           ++ + E  L       F AG ETT  TL   +  +AL P IQ+ +  E+           
Sbjct: 293 TSSFHEENLICSTLDLFFAGTETTSTTLRWALLYMALYPEIQEKVQAEIDRVIGQGQQPS 352

Query: 230 YENIGELKYLDCVLNETMRKWSAA-IFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTV 288
                 + Y + V++E  R  +   + V R  T    L           L  G +I   +
Sbjct: 353 TAARESMPYTNAVIHEVQRMGNIIPLNVPREVTVDTTLAG-------YHLPKGTMILTNL 405

Query: 289 NSIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFR 348
            ++H DP  +  P+ F P+ FL+  + K K   FMPF +G R C+G + A  E+ I    
Sbjct: 406 TALHRDPTEWATPDTFNPDHFLENGQFK-KREAFMPFSIGKRACLGEQLARTELFIFFTS 464

Query: 349 LMLNF 353
           LM  F
Sbjct: 465 LMQKF 469


>M29874-1|AAA52144.1|  491|Homo sapiens CYP2B protein.
          Length = 491

 Score = 64.5 bits (150), Expect = 6e-10
 Identities = 48/186 (25%), Positives = 80/186 (43%), Gaps = 8/186 (4%)

Query: 171 TEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVY 230
           +E++   L       F AG ETT  TL      +   PH+ + +Y E++           
Sbjct: 281 SEFSHQNLNLNTLSLFFAGTETTSTTLRYGFLLMLKYPHVAERVYREIEQVIGPHRPPEL 340

Query: 231 ENIGELKYLDCVLNETMRKWSAAIFVDRI-CTKPYVLPPPREGGKPCQLKPGEVIYNTVN 289
            +  ++ Y + V+ E  R      F D +    P+++            K  EV      
Sbjct: 341 HDRAKMPYTEAVIYEIQR------FSDLLPMGVPHIVTQHTSFRGYIIPKDTEVFLILST 394

Query: 290 SIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRL 349
           ++H DP Y+E+P+ F P+ FLD N    K   F+PF +G R C+G   A  E+ +    +
Sbjct: 395 ALH-DPHYFEKPDAFNPDHFLDANGALKKTEAFIPFSLGKRICLGEGIARAELFLFFTTI 453

Query: 350 MLNFKV 355
           + NF +
Sbjct: 454 LQNFSM 459


>K03192-1|AAA52147.1|  331|Homo sapiens CYP1A1 protein.
          Length = 331

 Score = 64.5 bits (150), Expect = 6e-10
 Identities = 54/208 (25%), Positives = 93/208 (44%), Gaps = 15/208 (7%)

Query: 170 STEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLV 229
           +TE+   +L       F+ G ET   TL      L   P ++  ++EE+           
Sbjct: 120 NTEFYLEKLVMTSLNLFIGGTETVSTTLRYGFLLLIKHPGVEAKVHEEIDRVIGKNRQPK 179

Query: 230 YENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQ---LKPGEVIYN 286
           +E+  ++ Y++ +++E  R      F D I   P + P   +     +   L  G  +Y 
Sbjct: 180 FEDRAKMPYMEAMIHEIQR------FGDVI---PMIWPGRVKKDTKFRDFFLPKGTEVYP 230

Query: 287 TVNSIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILL 346
            + S+  DPI+  +P+ F P+ F +      K   F+PF +G   C G   A ME+ +  
Sbjct: 231 MLGSVLRDPIFLSKPQDFNPQHFTELEGAPKKSDAFVPFSIGQPNCFGEGLARMELFLFF 290

Query: 347 FRLMLNFKVLKCAKTLDPIKMSP--VGF 372
             +M NF+ LK +++   I +SP  VGF
Sbjct: 291 TTVMQNFR-LKSSQSPKDIDVSPKHVGF 317


>DQ298753-1|ABB84469.1|  491|Homo sapiens cytochrome P450, family 2,
           subfamily B, polypeptide 6 protein.
          Length = 491

 Score = 64.5 bits (150), Expect = 6e-10
 Identities = 48/186 (25%), Positives = 80/186 (43%), Gaps = 8/186 (4%)

Query: 171 TEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVY 230
           +E++   L       F AG ETT  TL      +   PH+ + +Y E++           
Sbjct: 281 SEFSHQNLNLNTLSLFFAGTETTSTTLRYGFLLMLKYPHVAERVYREIEQVIGPHRPPEL 340

Query: 231 ENIGELKYLDCVLNETMRKWSAAIFVDRI-CTKPYVLPPPREGGKPCQLKPGEVIYNTVN 289
            +  ++ Y + V+ E  R      F D +    P+++            K  EV      
Sbjct: 341 HDRAKMPYTEAVIYEIQR------FSDLLPMGVPHIVTQHTSFRGYIIPKDTEVFLILST 394

Query: 290 SIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRL 349
           ++H DP Y+E+P+ F P+ FLD N    K   F+PF +G R C+G   A  E+ +    +
Sbjct: 395 ALH-DPHYFEKPDAFNPDHFLDANGALKKTEAFIPFSLGKRICLGEGIARAELFLFFTTI 453

Query: 350 MLNFKV 355
           + NF +
Sbjct: 454 LQNFSM 459


>BC067431-1|AAH67431.1|  491|Homo sapiens cytochrome P450, family 2,
           subfamily B, polypeptide 6 protein.
          Length = 491

 Score = 64.5 bits (150), Expect = 6e-10
 Identities = 48/186 (25%), Positives = 80/186 (43%), Gaps = 8/186 (4%)

Query: 171 TEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVY 230
           +E++   L       F AG ETT  TL      +   PH+ + +Y E++           
Sbjct: 281 SEFSHQNLNLNTLSLFFAGTETTSTTLRYGFLLMLKYPHVAERVYREIEQVIGPHRPPEL 340

Query: 231 ENIGELKYLDCVLNETMRKWSAAIFVDRI-CTKPYVLPPPREGGKPCQLKPGEVIYNTVN 289
            +  ++ Y + V+ E  R      F D +    P+++            K  EV      
Sbjct: 341 HDRAKMPYTEAVIYEIQR------FSDLLPMGVPHIVTQHTSFRGYIIPKDTEVFLILST 394

Query: 290 SIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRL 349
           ++H DP Y+E+P+ F P+ FLD N    K   F+PF +G R C+G   A  E+ +    +
Sbjct: 395 ALH-DPHYFEKPDAFNPDHFLDANGALKKTEAFIPFSLGKRICLGEGIARAELFLFFTTI 453

Query: 350 MLNFKV 355
           + NF +
Sbjct: 454 LQNFSM 459


>BC067430-1|AAH67430.1|  491|Homo sapiens cytochrome P450, family 2,
           subfamily B, polypeptide 6 protein.
          Length = 491

 Score = 64.5 bits (150), Expect = 6e-10
 Identities = 48/186 (25%), Positives = 80/186 (43%), Gaps = 8/186 (4%)

Query: 171 TEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVY 230
           +E++   L       F AG ETT  TL      +   PH+ + +Y E++           
Sbjct: 281 SEFSHQNLNLNTLSLFFAGTETTSTTLRYGFLLMLKYPHVAERVYREIEQVIGPHRPPEL 340

Query: 231 ENIGELKYLDCVLNETMRKWSAAIFVDRI-CTKPYVLPPPREGGKPCQLKPGEVIYNTVN 289
            +  ++ Y + V+ E  R      F D +    P+++            K  EV      
Sbjct: 341 HDRAKMPYTEAVIYEIQR------FSDLLPMGVPHIVTQHTSFRGYIIPKDTEVFLILST 394

Query: 290 SIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRL 349
           ++H DP Y+E+P+ F P+ FLD N    K   F+PF +G R C+G   A  E+ +    +
Sbjct: 395 ALH-DPHYFEKPDAFNPDHFLDANGALKKTEAFIPFSLGKRICLGEGIARAELFLFFTTI 453

Query: 350 MLNFKV 355
           + NF +
Sbjct: 454 LQNFSM 459


>AF372573-1|AAL69652.1|  495|Homo sapiens cytochrome P450 2F1
           protein.
          Length = 495

 Score = 64.5 bits (150), Expect = 6e-10
 Identities = 50/170 (29%), Positives = 76/170 (44%), Gaps = 12/170 (7%)

Query: 189 GFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYENIGELKYLDCVLNETMR 248
           G +T   TL +    L   P +Q  + EE+            ++   + Y D V++E  R
Sbjct: 303 GTKTVSTTLHHAFLALMKYPKVQARVQEEIDLVVGRARLPALKDRAAMPYTDAVIHEVQR 362

Query: 249 KWSAAIFVDRICTKPYVLPP--PREGGKPCQLKP-GEVIYNTVNSIHMDPIYYEEPEKFI 305
                 F D I   P  LP    R+      L P G  +   +N++H DP  +  P++F 
Sbjct: 363 ------FADII---PMNLPHRVTRDTAFRGFLIPKGTDVITLLNTVHYDPSQFLTPQEFN 413

Query: 306 PERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKV 355
           PE FLD N+   K   FMPF  G R C+G   A ME+ + L  ++ +F +
Sbjct: 414 PEHFLDANQSFKKSPAFMPFSAGRRLCLGESLARMELFLYLTAILQSFSL 463


>AF182277-1|AAF13602.1|  491|Homo sapiens cytochrome P450-2B6
           protein.
          Length = 491

 Score = 64.5 bits (150), Expect = 6e-10
 Identities = 48/186 (25%), Positives = 80/186 (43%), Gaps = 8/186 (4%)

Query: 171 TEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVY 230
           +E++   L       F AG ETT  TL      +   PH+ + +Y E++           
Sbjct: 281 SEFSHQNLNLNTLSLFFAGTETTSTTLRYGFLLMLKYPHVAERVYREIEQVIGPHRPPEL 340

Query: 231 ENIGELKYLDCVLNETMRKWSAAIFVDRI-CTKPYVLPPPREGGKPCQLKPGEVIYNTVN 289
            +  ++ Y + V+ E  R      F D +    P+++            K  EV      
Sbjct: 341 HDRAKMPYTEAVIYEIQR------FSDLLPMGVPHIVTQHTSFRGYIIPKDTEVFLILST 394

Query: 290 SIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRL 349
           ++H DP Y+E+P+ F P+ FLD N    K   F+PF +G R C+G   A  E+ +    +
Sbjct: 395 ALH-DPHYFEKPDAFNPDHFLDANGALKKTEAFIPFSLGKRICLGEGIARAELFLFFTTI 453

Query: 350 MLNFKV 355
           + NF +
Sbjct: 454 LQNFSM 459


>AC023172-1|AAF32444.1|  491|Homo sapiens CYP2B6 protein.
          Length = 491

 Score = 64.5 bits (150), Expect = 6e-10
 Identities = 48/186 (25%), Positives = 80/186 (43%), Gaps = 8/186 (4%)

Query: 171 TEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVY 230
           +E++   L       F AG ETT  TL      +   PH+ + +Y E++           
Sbjct: 281 SEFSHQNLNLNTLSLFFAGTETTSTTLRYGFLLMLKYPHVAERVYREIEQVIGPHRPPEL 340

Query: 231 ENIGELKYLDCVLNETMRKWSAAIFVDRI-CTKPYVLPPPREGGKPCQLKPGEVIYNTVN 289
            +  ++ Y + V+ E  R      F D +    P+++            K  EV      
Sbjct: 341 HDRAKMPYTEAVIYEIQR------FSDLLPMGVPHIVTQHTSFRGYIIPKDTEVFLILST 394

Query: 290 SIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRL 349
           ++H DP Y+E+P+ F P+ FLD N    K   F+PF +G R C+G   A  E+ +    +
Sbjct: 395 ALH-DPHYFEKPDAFNPDHFLDANGALKKTEAFIPFSLGKRICLGEGIARAELFLFFTTI 453

Query: 350 MLNFKV 355
           + NF +
Sbjct: 454 LQNFSM 459


>AB080265-1|BAB85489.1|  502|Homo sapiens cytochrome P450 2J2
           protein.
          Length = 502

 Score = 64.5 bits (150), Expect = 6e-10
 Identities = 51/185 (27%), Positives = 78/185 (42%), Gaps = 9/185 (4%)

Query: 170 STEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLV 229
           ++ + E  L       F AG ETT  TL   +  +AL P IQ+ +  E+           
Sbjct: 293 TSSFHEENLICSTLDLFFAGTETTSTTLRWALLYMALYPEIQEKVQVEIDRVIGQGQQPS 352

Query: 230 YENIGELKYLDCVLNETMRKWSAA-IFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTV 288
                 + Y + V++E  R  +   + V R  T    L           L  G +I   +
Sbjct: 353 TAARESMPYTNAVIHEVQRMGNIIPLNVPREVTVDTTLAG-------YHLPKGTMILTNL 405

Query: 289 NSIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFR 348
            ++H DP  +  P+ F P+ FL+  + K K   FMPF +G R C+G + A  E+ I    
Sbjct: 406 TALHRDPTEWATPDTFNPDHFLENGQFK-KREAFMPFSIGKRACLGEQLARTELFIFFTS 464

Query: 349 LMLNF 353
           LM  F
Sbjct: 465 LMQKF 469


>X58906-1|CAA41709.1|  495|Homo sapiens steroid 21-monooxygenase
           protein.
          Length = 495

 Score = 64.1 bits (149), Expect = 8e-10
 Identities = 50/187 (26%), Positives = 82/187 (43%), Gaps = 15/187 (8%)

Query: 187 VAGFETTGNTLINCIHELALSPHIQDILYEELK---AFKETKGNLVYENIGELKYLDCVL 243
           + G ETT NTL   +  L   P IQ  L EEL        +   + Y++   L  L+  +
Sbjct: 291 IGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDHARLPLLNATI 350

Query: 244 NETMR-KWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHMDPIYYEEPE 302
            E +R +    + +    T+P  +           +  G VI   +   H+D   +E P 
Sbjct: 351 AEVLRLRPVVPLALPHRTTRPSSI-------SGYDIPEGTVIIPNLQGAHLDETVWERPH 403

Query: 303 KFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVLKCAKTL 362
           +F P+RFL+  K+       + FG G R C+G   A +E+ ++L RL+  F +L     L
Sbjct: 404 EFWPDRFLEPGKNS----RALAFGCGARVCLGEPLARLELFVVLTRLLQAFTLLSSGDAL 459

Query: 363 DPIKMSP 369
             ++  P
Sbjct: 460 PSLQPLP 466


>M28548-1|AAA52065.1|  495|Homo sapiens protein ( Human mutant
           21-hydroxylase B gene, complete cds. ).
          Length = 495

 Score = 64.1 bits (149), Expect = 8e-10
 Identities = 58/223 (26%), Positives = 95/223 (42%), Gaps = 24/223 (10%)

Query: 160 RDMIQLLMQLSTEWTETELAAQLFV---------FFVAGFETTGNTLINCIHELALSPHI 210
           RDM+  ++Q   + T  E + QL             + G ETT NTL   +  L   P I
Sbjct: 255 RDMMDYMLQGVAQPTMEEGSGQLLEGHVHMAAVDLLIGGTETTANTLSWAVVFLLHHPEI 314

Query: 211 QDILYEELK---AFKETKGNLVYENIGELKYLDCVLNETMR-KWSAAIFVDRICTKPYVL 266
           Q  L EEL        +   + Y++   L  L+  + E +R +    + +    T+P  +
Sbjct: 315 QQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVVPLALPHRTTRPSSI 374

Query: 267 PPPREGGKPCQLKPGEVIYNTVNSIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFG 326
                      +  G VI   +   H+D   +E P +F P+RFL+  K+       + FG
Sbjct: 375 -------SGYDIPEGTVIIPNLQGAHLDETVWERPHEFWPDRFLEPGKNS----RALAFG 423

Query: 327 VGPRYCIGSRFALMEMKILLFRLMLNFKVLKCAKTLDPIKMSP 369
            G R C+G   A +E+ ++L RL+  F +L     L  ++  P
Sbjct: 424 CGARVCLGEPLARLELFVVLTRLLQAFTLLPSGDALPSLQPLP 466


>J02906-1|AAA52156.1|  491|Homo sapiens CYP2F1 protein.
          Length = 491

 Score = 64.1 bits (149), Expect = 8e-10
 Identities = 50/170 (29%), Positives = 76/170 (44%), Gaps = 12/170 (7%)

Query: 189 GFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNLVYENIGELKYLDCVLNETMR 248
           G +T   TL +    L   P +Q  + EE+            ++   + Y D V++E  R
Sbjct: 299 GTKTVSTTLHHAFLALMKYPKVQARVQEEIDLVVGRARLPALKDRAAMPYTDAVIHEVQR 358

Query: 249 KWSAAIFVDRICTKPYVLPP--PREGGKPCQLKP-GEVIYNTVNSIHMDPIYYEEPEKFI 305
                 F D I   P  LP    R+      L P G  +   +N++H DP  +  P++F 
Sbjct: 359 ------FADII---PMNLPHRVTRDTAFRGFLIPKGTDVITLLNTVHYDPSQFLTPQEFN 409

Query: 306 PERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKV 355
           PE FLD N+   K   FMPF  G R C+G   A ME+ + L  ++ +F +
Sbjct: 410 PEHFLDANQSFKKSPAFMPFSAGRRLCLGELLARMELFLYLTAILQSFSL 459


>M26856-1|AAA52064.1|  495|Homo sapiens protein ( Human
           21-hydroxylase B gene, complete cds. ).
          Length = 495

 Score = 63.7 bits (148), Expect = 1e-09
 Identities = 50/187 (26%), Positives = 82/187 (43%), Gaps = 15/187 (8%)

Query: 187 VAGFETTGNTLINCIHELALSPHIQDILYEELK---AFKETKGNLVYENIGELKYLDCVL 243
           + G ETT NTL   +  L   P IQ  L EEL        +   + Y++   L  L+  +
Sbjct: 291 IGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATI 350

Query: 244 NETMR-KWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHMDPIYYEEPE 302
            E +R +    + +    T+P  +           +  G VI   +   H+D   +E P 
Sbjct: 351 AEVLRLRPVVPLALPHRTTRPSSI-------SGYDIPEGTVIIPNLQGAHLDETVWERPH 403

Query: 303 KFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVLKCAKTL 362
           +F P+RFL+  K+       + FG G R C+G   A +E+ ++L RL+  F +L     L
Sbjct: 404 EFWPDRFLEPGKNS----RALAFGCGARVCLGEPLARLELFVVLTRLLQAFTLLPSGDAL 459

Query: 363 DPIKMSP 369
             ++  P
Sbjct: 460 PSLQPLP 466


>M24667-1|AAA52148.1|  256|Homo sapiens steroid 11-beta-hydroxylase
           protein.
          Length = 256

 Score = 63.7 bits (148), Expect = 1e-09
 Identities = 46/178 (25%), Positives = 82/178 (46%), Gaps = 8/178 (4%)

Query: 169 LSTEWTETELAAQLFVFFVAGFETTGNTLINCIHELALSPHIQDILYEELKAFKETKGNL 228
           L+ E +   + A          + T   L+  + ELA +P++Q  L +E  A   +    
Sbjct: 85  LNAELSPDAIKANCMELTAGSVDRTVFPLLMTLFELARNPNVQQPLRQESLAPAASISEH 144

Query: 229 VYENIGELKYLDCVLNETMRKWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTV 288
             +   EL  L   L ET+R +   + ++R+ +   VL       +   +  G ++   +
Sbjct: 145 PQKATTELPLLRAALKETLRLYPVGLILERVVSSDLVL-------QNYHIPAGTLVRVFL 197

Query: 289 NSIHMDPIYYEEPEKFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILL 346
            S+  +P  +  PE++ P+R+LD  K   + F  +PFG G R C+G R A  +M +LL
Sbjct: 198 YSLGRNPALFPRPERYNPQRWLDI-KGSGRNFYHVPFGFGMRQCLGRRLAEADMLLLL 254


>M21550-1|AAA52063.1|  495|Homo sapiens CYP21 protein.
          Length = 495

 Score = 63.7 bits (148), Expect = 1e-09
 Identities = 50/187 (26%), Positives = 82/187 (43%), Gaps = 15/187 (8%)

Query: 187 VAGFETTGNTLINCIHELALSPHIQDILYEELK---AFKETKGNLVYENIGELKYLDCVL 243
           + G ETT NTL   +  L   P IQ  L EEL        +   + Y++   L  L+  +
Sbjct: 291 IGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATI 350

Query: 244 NETMR-KWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHMDPIYYEEPE 302
            E +R +    + +    T+P  +           +  G VI   +   H+D   +E P 
Sbjct: 351 AEVLRLRPVVPLALPHRTTRPSSI-------SGYDIPEGTVIIPNLQGAHLDETVWERPH 403

Query: 303 KFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVLKCAKTL 362
           +F P+RFL+  K+       + FG G R C+G   A +E+ ++L RL+  F +L     L
Sbjct: 404 EFWPDRFLEPGKNS----RALAFGCGARVCLGEPLARLELFVVLTRLLQAFTLLPSGDAL 459

Query: 363 DPIKMSP 369
             ++  P
Sbjct: 460 PSLQPLP 466


>M13936-1|AAA59695.1|  494|Homo sapiens CYP21P protein.
          Length = 494

 Score = 63.7 bits (148), Expect = 1e-09
 Identities = 50/187 (26%), Positives = 82/187 (43%), Gaps = 15/187 (8%)

Query: 187 VAGFETTGNTLINCIHELALSPHIQDILYEELK---AFKETKGNLVYENIGELKYLDCVL 243
           + G ETT NTL   +  L   P IQ  L EEL        +   + Y++   L  L+  +
Sbjct: 290 IGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATI 349

Query: 244 NETMR-KWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHMDPIYYEEPE 302
            E +R +    + +    T+P  +           +  G VI   +   H+D   +E P 
Sbjct: 350 AEVLRLRPVVPLALPHRTTRPSSI-------SGYDIPEGTVIIPNLQGAHLDETVWERPH 402

Query: 303 KFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVLKCAKTL 362
           +F P+RFL+  K+       + FG G R C+G   A +E+ ++L RL+  F +L     L
Sbjct: 403 EFWPDRFLEPGKNS----RALAFGCGARVCLGEPLARLELFVVLTRLLQAFTLLPSGDAL 458

Query: 363 DPIKMSP 369
             ++  P
Sbjct: 459 PSLQPLP 465


>BX679671-8|CAM26071.1|  464|Homo sapiens cytochrome P450, family
           21, subfamily A, polypeptide 2 protein.
          Length = 464

 Score = 63.7 bits (148), Expect = 1e-09
 Identities = 50/187 (26%), Positives = 82/187 (43%), Gaps = 15/187 (8%)

Query: 187 VAGFETTGNTLINCIHELALSPHIQDILYEELK---AFKETKGNLVYENIGELKYLDCVL 243
           + G ETT NTL   +  L   P IQ  L EEL        +   + Y++   L  L+  +
Sbjct: 260 IGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATI 319

Query: 244 NETMR-KWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHMDPIYYEEPE 302
            E +R +    + +    T+P  +           +  G VI   +   H+D   +E P 
Sbjct: 320 AEVLRLRPVVPLALPHRTTRPSSI-------SGYDIPEGTVIIPNLQGAHLDETVWERPH 372

Query: 303 KFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVLKCAKTL 362
           +F P+RFL+  K+       + FG G R C+G   A +E+ ++L RL+  F +L     L
Sbjct: 373 EFWPDRFLEPGKNS----RALAFGCGARVCLGEPLARLELFVVLTRLLQAFTLLPSGDAL 428

Query: 363 DPIKMSP 369
             ++  P
Sbjct: 429 PSLQPLP 435


>BX679671-7|CAM26070.1|  494|Homo sapiens cytochrome P450, family
           21, subfamily A, polypeptide 2 protein.
          Length = 494

 Score = 63.7 bits (148), Expect = 1e-09
 Identities = 50/187 (26%), Positives = 82/187 (43%), Gaps = 15/187 (8%)

Query: 187 VAGFETTGNTLINCIHELALSPHIQDILYEELK---AFKETKGNLVYENIGELKYLDCVL 243
           + G ETT NTL   +  L   P IQ  L EEL        +   + Y++   L  L+  +
Sbjct: 290 IGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATI 349

Query: 244 NETMR-KWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHMDPIYYEEPE 302
            E +R +    + +    T+P  +           +  G VI   +   H+D   +E P 
Sbjct: 350 AEVLRLRPVVPLALPHRTTRPSSI-------SGYDIPEGTVIIPNLQGAHLDETVWERPH 402

Query: 303 KFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVLKCAKTL 362
           +F P+RFL+  K+       + FG G R C+G   A +E+ ++L RL+  F +L     L
Sbjct: 403 EFWPDRFLEPGKNS----RALAFGCGARVCLGEPLARLELFVVLTRLLQAFTLLPSGDAL 458

Query: 363 DPIKMSP 369
             ++  P
Sbjct: 459 PSLQPLP 465


>BC125182-1|AAI25183.1|  494|Homo sapiens cytochrome P450, family
           21, subfamily A, polypeptide 2 protein.
          Length = 494

 Score = 63.7 bits (148), Expect = 1e-09
 Identities = 50/187 (26%), Positives = 82/187 (43%), Gaps = 15/187 (8%)

Query: 187 VAGFETTGNTLINCIHELALSPHIQDILYEELK---AFKETKGNLVYENIGELKYLDCVL 243
           + G ETT NTL   +  L   P IQ  L EEL        +   + Y++   L  L+  +
Sbjct: 290 IGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATI 349

Query: 244 NETMR-KWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHMDPIYYEEPE 302
            E +R +    + +    T+P  +           +  G VI   +   H+D   +E P 
Sbjct: 350 AEVLRLRPVVPLALPHRTTRPSSI-------SGYDIPEGTVIIPNLQGAHLDETVWERPH 402

Query: 303 KFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVLKCAKTL 362
           +F P+RFL+  K+       + FG G R C+G   A +E+ ++L RL+  F +L     L
Sbjct: 403 EFWPDRFLEPGKNS----RALAFGCGARVCLGEPLARLELFVVLTRLLQAFTLLPSGDAL 458

Query: 363 DPIKMSP 369
             ++  P
Sbjct: 459 PSLQPLP 465


>BC125181-1|AAI25182.1|  495|Homo sapiens cytochrome P450, family
           21, subfamily A, polypeptide 2 protein.
          Length = 495

 Score = 63.7 bits (148), Expect = 1e-09
 Identities = 50/187 (26%), Positives = 82/187 (43%), Gaps = 15/187 (8%)

Query: 187 VAGFETTGNTLINCIHELALSPHIQDILYEELK---AFKETKGNLVYENIGELKYLDCVL 243
           + G ETT NTL   +  L   P IQ  L EEL        +   + Y++   L  L+  +
Sbjct: 291 IGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATI 350

Query: 244 NETMR-KWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHMDPIYYEEPE 302
            E +R +    + +    T+P  +           +  G VI   +   H+D   +E P 
Sbjct: 351 AEVLRLRPVVPLALPHRTTRPSSI-------SGYDIPEGTVIIPNLQGAHLDETVWERPH 403

Query: 303 KFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVLKCAKTL 362
           +F P+RFL+  K+       + FG G R C+G   A +E+ ++L RL+  F +L     L
Sbjct: 404 EFWPDRFLEPGKNS----RALAFGCGARVCLGEPLARLELFVVLTRLLQAFTLLPSGDAL 459

Query: 363 DPIKMSP 369
             ++  P
Sbjct: 460 PSLQPLP 466


>AM183951-1|CAJ75805.1|  494|Homo sapiens steroid 21-hydroxylase,
           CYP21 protein.
          Length = 494

 Score = 63.7 bits (148), Expect = 1e-09
 Identities = 50/187 (26%), Positives = 82/187 (43%), Gaps = 15/187 (8%)

Query: 187 VAGFETTGNTLINCIHELALSPHIQDILYEELK---AFKETKGNLVYENIGELKYLDCVL 243
           + G ETT NTL   +  L   P IQ  L EEL        +   + Y++   L  L+  +
Sbjct: 290 IGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATI 349

Query: 244 NETMR-KWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHMDPIYYEEPE 302
            E +R +    + +    T+P  +           +  G VI   +   H+D   +E P 
Sbjct: 350 AEVLRLRPVVPLALPHRTTRPSSI-------SGYDIPEGTVIIPNLQGAHLDETVWERPH 402

Query: 303 KFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVLKCAKTL 362
           +F P+RFL+  K+       + FG G R C+G   A +E+ ++L RL+  F +L     L
Sbjct: 403 EFWPDRFLEPGKNS----RALAFGCGARVCLGEPLARLELFVVLTRLLQAFTLLPSGDAL 458

Query: 363 DPIKMSP 369
             ++  P
Sbjct: 459 PSLQPLP 465


>AM183947-1|CAJ75801.1|  494|Homo sapiens steroid 21-hydroxylase,
           CYP21 protein.
          Length = 494

 Score = 63.7 bits (148), Expect = 1e-09
 Identities = 50/187 (26%), Positives = 82/187 (43%), Gaps = 15/187 (8%)

Query: 187 VAGFETTGNTLINCIHELALSPHIQDILYEELK---AFKETKGNLVYENIGELKYLDCVL 243
           + G ETT NTL   +  L   P IQ  L EEL        +   + Y++   L  L+  +
Sbjct: 290 IGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATI 349

Query: 244 NETMR-KWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHMDPIYYEEPE 302
            E +R +    + +    T+P  +           +  G VI   +   H+D   +E P 
Sbjct: 350 AEVLRLRPVVPLALPHRTTRPSSI-------SGYDIPEGTVIIPNLQGAHLDETVWERPH 402

Query: 303 KFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVLKCAKTL 362
           +F P+RFL+  K+       + FG G R C+G   A +E+ ++L RL+  F +L     L
Sbjct: 403 EFWPDRFLEPGKNS----RALAFGCGARVCLGEPLARLELFVVLTRLLQAFTLLPSGDAL 458

Query: 363 DPIKMSP 369
             ++  P
Sbjct: 459 PSLQPLP 465


>AM183946-1|CAJ75800.1|  494|Homo sapiens steroid 21-hydroxylase,
           CYP21 protein.
          Length = 494

 Score = 63.7 bits (148), Expect = 1e-09
 Identities = 50/187 (26%), Positives = 82/187 (43%), Gaps = 15/187 (8%)

Query: 187 VAGFETTGNTLINCIHELALSPHIQDILYEELK---AFKETKGNLVYENIGELKYLDCVL 243
           + G ETT NTL   +  L   P IQ  L EEL        +   + Y++   L  L+  +
Sbjct: 290 IGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATI 349

Query: 244 NETMR-KWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHMDPIYYEEPE 302
            E +R +    + +    T+P  +           +  G VI   +   H+D   +E P 
Sbjct: 350 AEVLRLRPVVPLALPHRTTRPSSI-------SGYDIPEGTVIIPNLQGAHLDETVWERPH 402

Query: 303 KFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVLKCAKTL 362
           +F P+RFL+  K+       + FG G R C+G   A +E+ ++L RL+  F +L     L
Sbjct: 403 EFWPDRFLEPGKNS----RALAFGCGARVCLGEPLARLELFVVLTRLLQAFTLLPSGDAL 458

Query: 363 DPIKMSP 369
             ++  P
Sbjct: 459 PSLQPLP 465


>AM183945-1|CAJ75799.1|  494|Homo sapiens steroid 21-hydroxylase,
           CYP21 protein.
          Length = 494

 Score = 63.7 bits (148), Expect = 1e-09
 Identities = 50/187 (26%), Positives = 82/187 (43%), Gaps = 15/187 (8%)

Query: 187 VAGFETTGNTLINCIHELALSPHIQDILYEELK---AFKETKGNLVYENIGELKYLDCVL 243
           + G ETT NTL   +  L   P IQ  L EEL        +   + Y++   L  L+  +
Sbjct: 290 IGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATI 349

Query: 244 NETMR-KWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHMDPIYYEEPE 302
            E +R +    + +    T+P  +           +  G VI   +   H+D   +E P 
Sbjct: 350 AEVLRLRPVVPLALPHRTTRPSSI-------SGYDIPEGTVIIPNLQGAHLDETVWERPH 402

Query: 303 KFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVLKCAKTL 362
           +F P+RFL+  K+       + FG G R C+G   A +E+ ++L RL+  F +L     L
Sbjct: 403 EFWPDRFLEPGKNS----RALAFGCGARVCLGEPLARLELFVVLTRLLQAFTLLPSGDAL 458

Query: 363 DPIKMSP 369
             ++  P
Sbjct: 459 PSLQPLP 465


>AM086565-1|CAJ31104.1|  494|Homo sapiens steroid 21-hydroxylase,
           CYP21 protein.
          Length = 494

 Score = 63.7 bits (148), Expect = 1e-09
 Identities = 50/187 (26%), Positives = 82/187 (43%), Gaps = 15/187 (8%)

Query: 187 VAGFETTGNTLINCIHELALSPHIQDILYEELK---AFKETKGNLVYENIGELKYLDCVL 243
           + G ETT NTL   +  L   P IQ  L EEL        +   + Y++   L  L+  +
Sbjct: 290 IGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATI 349

Query: 244 NETMR-KWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHMDPIYYEEPE 302
            E +R +    + +    T+P  +           +  G VI   +   H+D   +E P 
Sbjct: 350 AEVLRLRPVVPLALPHRTTRPSSI-------SGYDIPEGTVIIPNLQGTHLDETVWERPH 402

Query: 303 KFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVLKCAKTL 362
           +F P+RFL+  K+       + FG G R C+G   A +E+ ++L RL+  F +L     L
Sbjct: 403 EFWPDRFLEPGKNS----RALAFGCGARVCLGEPLARLELFVVLTRLLQAFTLLPSGDAL 458

Query: 363 DPIKMSP 369
             ++  P
Sbjct: 459 PSLQPLP 465


>AM086564-1|CAJ31103.1|  494|Homo sapiens steroid 21-hydroxylase,
           CYP21 protein.
          Length = 494

 Score = 63.7 bits (148), Expect = 1e-09
 Identities = 50/187 (26%), Positives = 82/187 (43%), Gaps = 15/187 (8%)

Query: 187 VAGFETTGNTLINCIHELALSPHIQDILYEELK---AFKETKGNLVYENIGELKYLDCVL 243
           + G ETT NTL   +  L   P IQ  L EEL        +   + Y++   L  L+  +
Sbjct: 290 IGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATI 349

Query: 244 NETMR-KWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHMDPIYYEEPE 302
            E +R +    + +    T+P  +           +  G VI   +   H+D   +E P 
Sbjct: 350 AEVLRLRPVVPLALPHRTTRPSSI-------SGYDIPEGTVIIPNLQGAHLDETVWERPH 402

Query: 303 KFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVLKCAKTL 362
           +F P+RFL+  K+       + FG G R C+G   A +E+ ++L RL+  F +L     L
Sbjct: 403 EFWPDRFLEPGKNS----RALAFGCGARVCLGEPLARLELFVVLTRLLQAFTLLPSGDAL 458

Query: 363 DPIKMSP 369
             ++  P
Sbjct: 459 PSLQPLP 465


>AL929593-2|CAI41778.1|  465|Homo sapiens cytochrome P450, family
           21, subfamily A, polypeptide 2 protein.
          Length = 465

 Score = 63.7 bits (148), Expect = 1e-09
 Identities = 50/187 (26%), Positives = 82/187 (43%), Gaps = 15/187 (8%)

Query: 187 VAGFETTGNTLINCIHELALSPHIQDILYEELK---AFKETKGNLVYENIGELKYLDCVL 243
           + G ETT NTL   +  L   P IQ  L EEL        +   + Y++   L  L+  +
Sbjct: 261 IGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATI 320

Query: 244 NETMR-KWSAAIFVDRICTKPYVLPPPREGGKPCQLKPGEVIYNTVNSIHMDPIYYEEPE 302
            E +R +    + +    T+P  +           +  G VI   +   H+D   +E P 
Sbjct: 321 AEVLRLRPVVPLALPHRTTRPSSI-------SGYDIPEGTVIIPNLQGAHLDETVWERPH 373

Query: 303 KFIPERFLDENKHKIKPFTFMPFGVGPRYCIGSRFALMEMKILLFRLMLNFKVLKCAKTL 362
           +F P+RFL+  K+       + FG G R C+G   A +E+ ++L RL+  F +L     L
Sbjct: 374 EFWPDRFLEPGKNS----RALAFGCGARVCLGEPLARLELFVVLTRLLQAFTLLPSGDAL 429

Query: 363 DPIKMSP 369
             ++  P
Sbjct: 430 PSLQPLP 436


  Database: human
    Posted date:  Oct 5, 2007 11:13 AM
  Number of letters in database: 73,234,838
  Number of sequences in database:  224,733
  
Lambda     K      H
   0.323    0.140    0.428 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 60,496,120
Number of Sequences: 224733
Number of extensions: 2644597
Number of successful extensions: 7286
Number of sequences better than 10.0: 447
Number of HSP's better than 10.0 without gapping: 379
Number of HSP's successfully gapped in prelim test: 68
Number of HSP's that attempted gapping in prelim test: 6224
Number of HSP's gapped (non-prelim): 642
length of query: 389
length of database: 73,234,838
effective HSP length: 91
effective length of query: 298
effective length of database: 52,784,135
effective search space: 15729672230
effective search space used: 15729672230
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (22.0 bits)
S2: 66 (30.7 bits)