Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA002162-TA|BGIBMGA002162-PA|IPR002126|Cadherin
(900 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X87241-1|CAA60685.1| 4590|Homo sapiens homologue of Drosophila F... 130 2e-29
D87469-1|BAA13407.2| 2854|Homo sapiens KIAA0279 protein protein. 126 5e-28
AL390252-1|CAI13170.1| 2923|Homo sapiens cadherin, EGF LAG seven... 126 5e-28
AF234887-1|AAG00080.1| 2923|Homo sapiens FLAMINGO 1 protein. 126 5e-28
AB065955-1|BAC06168.1| 2923|Homo sapiens seven transmembrane hel... 126 5e-28
AY714129-1|AAU94938.1| 4186|Homo sapiens anchor protein protein. 118 7e-26
AF231023-1|AAF61929.1| 3312|Homo sapiens protocadherin Flamingo ... 118 7e-26
AY356402-1|AAR13653.1| 3222|Homo sapiens fat-like cadherin FATJ ... 113 3e-24
AB075518-1|BAE45762.1| 656|Homo sapiens putative protein produc... 112 6e-24
BC113416-1|AAI13417.1| 799|Homo sapiens cadherin 8, type 2 prot... 111 8e-24
AB035305-1|BAA87419.1| 799|Homo sapiens cadherin-8 protein. 111 8e-24
L34060-1|AAA35628.1| 793|Homo sapiens cadherin-8 protein. 109 3e-23
AB053446-1|BAB61903.2| 3434|Homo sapiens KIAA1773 protein protein. 108 1e-22
AL031597-2|CAI23555.1| 3014|Homo sapiens cadherin, EGF LAG seven... 107 1e-22
AL031588-3|CAI19319.1| 3014|Homo sapiens cadherin, EGF LAG seven... 107 1e-22
AL021392-2|CAI20967.1| 3014|Homo sapiens cadherin, EGF LAG seven... 107 1e-22
AF231024-1|AAF61930.1| 3014|Homo sapiens protocadherin Flamingo ... 107 1e-22
AY354497-1|AAR10443.1| 2916|Homo sapiens cadherin protein protein. 107 2e-22
BC047608-1|AAH47608.1| 794|Homo sapiens cadherin 12, type 2 (N-... 106 3e-22
L34057-1|AAA35623.1| 794|Homo sapiens cadherin-12 protein. 105 9e-22
L33477-1|AAB48539.1| 794|Homo sapiens Br-cadherin protein. 105 9e-22
AF152515-1|AAD43775.1| 820|Homo sapiens protocadherin gamma A8 ... 104 2e-21
AF152328-1|AAD43722.1| 932|Homo sapiens protocadherin gamma A8 ... 104 2e-21
AB002325-1|BAA20785.2| 898|Homo sapiens KIAA0327 protein protein. 104 2e-21
U59325-1|AAB02933.1| 790|Homo sapiens cadherin-14 protein. 103 2e-21
BC031051-1|AAH31051.1| 790|Homo sapiens cadherin 18, type 2 pro... 103 2e-21
BX537422-1|CAD97664.1| 1203|Homo sapiens hypothetical protein pr... 102 5e-21
AL603863-3|CAM17491.1| 1237|Homo sapiens protocadherin 9 protein. 102 5e-21
AL603863-2|CAH72759.1| 1203|Homo sapiens protocadherin 9 protein. 102 5e-21
AL603863-1|CAH72758.1| 1032|Homo sapiens protocadherin 9 protein. 102 5e-21
AL355173-2|CAH72612.1| 1203|Homo sapiens protocadherin 9 protein. 102 5e-21
AL355173-1|CAM17290.1| 1237|Homo sapiens protocadherin 9 protein. 102 5e-21
AL138814-1|CAM13066.1| 1237|Homo sapiens protocadherin 9 protein. 102 5e-21
AL136999-2|CAI12502.1| 1203|Homo sapiens protocadherin 9 protein. 102 5e-21
AL136999-1|CAM13771.1| 1237|Homo sapiens protocadherin 9 protein. 102 5e-21
AF169692-1|AAF89689.2| 1203|Homo sapiens protocadherin-9 protein. 102 5e-21
BC036062-1|AAH36062.1| 776|Homo sapiens protocadherin beta 16 p... 101 1e-20
BC113460-1|AAI13461.1| 813|Homo sapiens protocadherin gamma sub... 101 2e-20
BC104926-1|AAI04927.1| 813|Homo sapiens protocadherin gamma sub... 101 2e-20
AF152512-1|AAD43772.1| 813|Homo sapiens protocadherin gamma A5 ... 101 2e-20
AF152325-1|AAD43719.1| 931|Homo sapiens protocadherin gamma A5 ... 101 2e-20
BC112084-1|AAI12085.1| 823|Homo sapiens protocadherin gamma sub... 100 2e-20
BC112082-1|AAI12083.1| 823|Homo sapiens protocadherin gamma sub... 100 2e-20
AY013878-1|AAK21988.1| 776|Homo sapiens protocadherin beta 8a p... 100 2e-20
AF282973-2|AAG10030.1| 776|Homo sapiens protocadherin-3x protein. 100 2e-20
AF217757-1|AAF81914.1| 776|Homo sapiens protocadherin 3X protein. 100 2e-20
AF152507-1|AAD43768.1| 823|Homo sapiens protocadherin gamma A1 ... 100 2e-20
AF152318-1|AAD43712.1| 931|Homo sapiens protocadherin gamma A1 ... 100 2e-20
AB046841-1|BAB13447.1| 787|Homo sapiens KIAA1621 protein protein. 100 2e-20
BC113607-1|AAI13608.1| 803|Homo sapiens protocadherin gamma sub... 99 3e-20
BC112088-1|AAI12089.1| 803|Homo sapiens protocadherin gamma sub... 99 3e-20
AF152520-1|AAD43780.1| 803|Homo sapiens protocadherin gamma B4 ... 99 3e-20
AF152333-1|AAD43727.1| 923|Homo sapiens protocadherin gamma B4 ... 99 3e-20
AY010111-1|AAG27034.2| 3354|Homo sapiens cadherin 23 protein. 100 5e-20
AL772287-2|CAI13626.1| 3359|Homo sapiens cadherin-like 23 protein. 100 5e-20
AL731541-6|CAI40841.1| 3359|Homo sapiens cadherin-like 23 protein. 100 5e-20
AL359183-3|CAI13426.1| 3359|Homo sapiens cadherin-like 23 protein. 100 5e-20
AF312024-1|AAG48303.1| 3354|Homo sapiens cadherin related 23 pro... 100 5e-20
AF152514-1|AAD43774.1| 817|Homo sapiens protocadherin gamma A7 ... 99 6e-20
AF152327-1|AAD43721.1| 932|Homo sapiens protocadherin gamma A7 ... 99 6e-20
AF282973-3|AAG10032.1| 536|Homo sapiens protocadherin-beta9 pro... 99 8e-20
AF217749-1|AAF81913.1| 797|Homo sapiens protocadherin beta 9 pr... 99 8e-20
BC105640-1|AAI05641.1| 797|Homo sapiens protocadherin beta 9 pr... 98 1e-19
BC103494-1|AAI03495.1| 796|Homo sapiens PCDHB9 protein protein. 98 1e-19
AF152502-1|AAD43763.2| 797|Homo sapiens protocadherin beta 9 pr... 98 1e-19
BC105636-1|AAI05637.1| 797|Homo sapiens protocadherin beta 9 pr... 98 1e-19
BC100672-1|AAI00673.1| 797|Homo sapiens protocadherin beta 9 pr... 98 1e-19
BC045637-1|AAH45637.1| 795|Homo sapiens protocadherin beta 12 p... 98 1e-19
BC000059-1|AAH00059.2| 771|Homo sapiens CELSR1 protein protein. 98 1e-19
AL031687-1|CAB51587.2| 828|Homo sapiens cadherin-like 22 protein. 98 1e-19
AF217746-1|AAK51614.1| 795|Homo sapiens protocadherin-beta12 pr... 98 1e-19
AF152491-1|AAD43752.1| 795|Homo sapiens protocadherin beta 12 p... 98 1e-19
AB208959-1|BAD92196.1| 716|Homo sapiens protocadherin beta 9 pr... 98 1e-19
BC101805-1|AAI01806.1| 811|Homo sapiens protocadherin gamma sub... 97 2e-19
AF152518-1|AAD43778.1| 811|Homo sapiens protocadherin gamma B2 ... 97 2e-19
AF152331-1|AAD43725.1| 931|Homo sapiens protocadherin gamma B2 ... 97 2e-19
BC036786-1|AAH36786.1| 630|Homo sapiens CDH7 protein protein. 97 2e-19
AF152473-1|AAD43734.1| 818|Homo sapiens protocadherin alpha C1 ... 97 2e-19
AF152303-1|AAD43697.1| 963|Homo sapiens protocadherin alpha C1 ... 97 2e-19
AF231022-1|AAF61928.1| 4349|Homo sapiens protocadherin Fat 2 pro... 97 3e-19
L11370-1|AAA36419.1| 1026|Homo sapiens protocadherin 42 protein. 96 6e-19
BC035812-1|AAH35812.1| 1060|Homo sapiens protocadherin 1 protein. 96 6e-19
AJ007611-1|CAC13127.1| 784|Homo sapiens cadherin-7 protein. 96 6e-19
AJ007608-1|CAC22255.1| 963|Homo sapiens protocadherin alpha-C1 ... 96 6e-19
AB035301-1|BAA87415.1| 785|Homo sapiens cadherin-7 protein. 96 6e-19
BC113372-1|AAI13373.1| 792|Homo sapiens protocadherin alpha 12 ... 95 7e-19
BC112280-1|AAI12281.1| 792|Homo sapiens protocadherin alpha 12,... 95 7e-19
AF152477-1|AAD43738.1| 792|Homo sapiens protocadherin alpha 12 ... 95 7e-19
AF152308-1|AAD43702.1| 941|Homo sapiens protocadherin alpha 12 ... 95 7e-19
AC005609-2|AAC34315.1| 792|Homo sapiens KIAA0345-like 2 protein. 95 7e-19
AY358199-1|AAQ88566.1| 781|Homo sapiens CDH24 protein. 95 1e-18
AY260900-1|AAP20590.1| 781|Homo sapiens cadherin-24 protein. 95 1e-18
BC104950-1|AAI04951.1| 823|Homo sapiens protocadherin gamma sub... 95 1e-18
BC093871-1|AAH93871.1| 823|Homo sapiens protocadherin gamma sub... 95 1e-18
AF152508-1|AAD43769.1| 823|Homo sapiens protocadherin gamma A2 ... 95 1e-18
AF152322-1|AAD43716.1| 932|Homo sapiens protocadherin gamma A2 ... 95 1e-18
BC036674-1|AAH36674.1| 950|Homo sapiens PCDHA6 protein protein. 94 2e-18
AF217752-1|AAK51619.1| 794|Homo sapiens protocadherin-beta6 pro... 94 2e-18
AF152519-1|AAD43779.1| 814|Homo sapiens protocadherin gamma B3 ... 94 2e-18
AF152499-1|AAD43760.1| 794|Homo sapiens protocadherin beta 6 pr... 94 2e-18
AF152484-1|AAD43745.1| 803|Homo sapiens protocadherin alpha 6 s... 94 2e-18
AF152332-1|AAD43726.1| 929|Homo sapiens protocadherin gamma B3 ... 94 2e-18
AF152314-1|AAD43708.1| 950|Homo sapiens protocadherin alpha 6 p... 94 2e-18
AC005609-8|AAC34320.1| 803|Homo sapiens KIAA0345-like 8 protein. 94 2e-18
BC071934-1|AAH71934.1| 798|Homo sapiens protocadherin beta 13 p... 94 2e-18
BC051348-1|AAH51348.1| 798|Homo sapiens protocadherin beta 13 p... 94 2e-18
BC033068-1|AAH33068.1| 798|Homo sapiens protocadherin beta 13 p... 94 2e-18
AY358946-1|AAQ89305.1| 916|Homo sapiens cadherin FIB3 protein. 94 2e-18
AY358427-1|AAQ88793.1| 798|Homo sapiens PCDHB13 protein. 94 2e-18
AF217745-1|AAK51613.1| 798|Homo sapiens protocadherin-beta13 pr... 94 2e-18
AF152506-1|AAD43767.1| 820|Homo sapiens protocadherin gamma A12... 94 2e-18
AF152492-1|AAD43753.1| 798|Homo sapiens protocadherin beta 13 p... 94 2e-18
AF152321-1|AAD43715.1| 932|Homo sapiens protocadherin gamma A12... 94 2e-18
AB011160-1|BAA25514.2| 938|Homo sapiens KIAA0588 protein protein. 94 2e-18
AF152478-1|AAD43739.1| 807|Homo sapiens protocadherin alpha 13 ... 93 3e-18
AF152309-1|AAD43703.1| 950|Homo sapiens protocadherin alpha 13 ... 93 3e-18
AC005609-1|AAC34314.1| 807|Homo sapiens KIAA0345-like 1 protein. 93 3e-18
AB208924-1|BAD92161.1| 921|Homo sapiens protocadherin alpha 13 ... 93 3e-18
BC104804-1|AAI04805.1| 950|Homo sapiens protocadherin alpha 9 p... 93 4e-18
BC104802-1|AAI04803.1| 950|Homo sapiens protocadherin alpha 9 p... 93 4e-18
BC099728-1|AAH99728.1| 798|Homo sapiens protocadherin beta 14 p... 93 4e-18
BC098144-1|AAH98144.1| 797|Homo sapiens PCDHB14 protein protein. 93 4e-18
BC093879-1|AAH93879.1| 818|Homo sapiens protocadherin gamma sub... 93 4e-18
BC093877-1|AAH93877.1| 818|Homo sapiens protocadherin gamma sub... 93 4e-18
AJ007610-1|CAC22257.1| 950|Homo sapiens protocadherin alpha 9 p... 93 4e-18
AF217744-1|AAK51612.1| 798|Homo sapiens protocadherin-beta14 pr... 93 4e-18
AF152521-1|AAD43781.1| 818|Homo sapiens protocadherin gamma B5 ... 93 4e-18
AF152493-1|AAD43754.1| 798|Homo sapiens protocadherin beta 14 p... 93 4e-18
AF152487-1|AAD43748.1| 842|Homo sapiens protocadherin alpha 9 s... 93 4e-18
AF152334-1|AAD43728.1| 923|Homo sapiens protocadherin gamma B5 ... 93 4e-18
AF152317-1|AAD43711.1| 950|Homo sapiens protocadherin alpha 9 p... 93 4e-18
AC005609-5|AAC34313.1| 842|Homo sapiens KIAA0345-like 5 protein. 93 4e-18
AB002343-1|BAA20803.2| 845|Homo sapiens KIAA0345 protein. 93 4e-18
BC112083-1|AAI12084.1| 878|Homo sapiens protocadherin gamma sub... 93 5e-18
BC112081-1|AAI12082.1| 878|Homo sapiens protocadherin gamma sub... 93 5e-18
AY563166-1|AAT72166.1| 1079|Homo sapiens cadherin 23 isoform B2 ... 93 5e-18
AY563165-1|AAT72165.1| 1114|Homo sapiens cadherin 23 isoform B1 ... 93 5e-18
AF152526-1|AAD43786.1| 878|Homo sapiens protocadherin gamma C5 ... 93 5e-18
AF152339-1|AAD43733.1| 944|Homo sapiens protocadherin gamma C5 ... 93 5e-18
AB209225-1|BAD92462.1| 799|Homo sapiens protocadherin beta 11 p... 93 5e-18
AB053445-1|BAB61902.1| 1147|Homo sapiens KIAA1774 protein protein. 93 5e-18
BC113611-1|AAI13612.1| 797|Homo sapiens protocadherin beta 11 p... 92 7e-18
BC112132-1|AAI12133.1| 797|Homo sapiens protocadherin beta 11 p... 92 7e-18
BC065284-1|AAH65284.1| 1381|Homo sapiens CDH23 protein protein. 92 7e-18
BC032581-1|AAH32581.1| 1061|Homo sapiens CDH23 protein protein. 92 7e-18
BC011570-1|AAH11570.1| 530|Homo sapiens cadherin-like 23 protein. 92 7e-18
AY358617-1|AAQ88980.1| 530|Homo sapiens CDH23 protein. 92 7e-18
AL772287-1|CAI13625.2| 1066|Homo sapiens cadherin-like 23 protein. 92 7e-18
AL731541-5|CAM20296.1| 1066|Homo sapiens cadherin-like 23 protein. 92 7e-18
AL359183-2|CAI13425.2| 1066|Homo sapiens cadherin-like 23 protein. 92 7e-18
AF217747-1|AAK51615.1| 797|Homo sapiens protocadherin-beta11 pr... 92 7e-18
AF152490-1|AAD43751.1| 797|Homo sapiens protocadherin beta 11 p... 92 7e-18
AB208958-1|BAD92195.1| 895|Homo sapiens protocadherin gamma sub... 92 7e-18
D31784-1|BAA06562.1| 790|Homo sapiens cadherin-6 protein. 91 1e-17
BC000019-1|AAH00019.1| 663|Homo sapiens CDH6 protein protein. 91 1e-17
AF152485-1|AAD43746.1| 789|Homo sapiens protocadherin alpha 7 s... 91 1e-17
AF152481-1|AAD43742.1| 824|Homo sapiens protocadherin alpha 3 s... 91 1e-17
AF152315-1|AAD43709.1| 937|Homo sapiens protocadherin alpha 7 p... 91 1e-17
AF152311-1|AAD43705.1| 950|Homo sapiens protocadherin alpha 3 p... 91 1e-17
AC005609-11|AAC34323.1| 824|Homo sapiens KIAA0345-like 11 protein. 91 1e-17
AC005609-7|AAC34319.1| 789|Homo sapiens KIAA0345-like 7 protein. 91 1e-17
BC113609-1|AAI13610.1| 798|Homo sapiens protocadherin alpha 4 p... 91 2e-17
BC112102-1|AAI12103.1| 798|Homo sapiens protocadherin alpha 4, ... 91 2e-17
BC093875-1|AAH93875.1| 850|Homo sapiens protocadherin gamma sub... 91 2e-17
BC093873-1|AAH93873.1| 850|Homo sapiens protocadherin gamma sub... 91 2e-17
AF152486-1|AAD43747.1| 814|Homo sapiens protocadherin alpha 8 s... 91 2e-17
AF152482-1|AAD43743.1| 798|Homo sapiens protocadherin alpha 4 s... 91 2e-17
AF152316-1|AAD43710.1| 950|Homo sapiens protocadherin alpha 8 p... 91 2e-17
AF152312-1|AAD43706.1| 947|Homo sapiens protocadherin alpha 4 p... 91 2e-17
AC005609-10|AAC34322.1| 798|Homo sapiens KIAA0345-like 10 protein. 91 2e-17
AC005609-6|AAC34318.1| 814|Homo sapiens KIAA0345-like 6 protein. 91 2e-17
AB208925-1|BAD92162.1| 921|Homo sapiens protocadherin alpha 4 i... 91 2e-17
AF169694-1|AAF89691.1| 695|Homo sapiens protocadherin alpha 6 a... 91 2e-17
AF152503-1|AAD43764.1| 850|Homo sapiens protocadherin gamma A10... 91 2e-17
AF152319-1|AAD43713.1| 936|Homo sapiens protocadherin gamma A10... 91 2e-17
BC129807-1|AAI29808.1| 824|Homo sapiens protocadherin alpha 3 p... 90 3e-17
BC051788-1|AAH51788.1| 929|Homo sapiens protocadherin gamma sub... 89 5e-17
AF152523-1|AAD43783.1| 808|Homo sapiens protocadherin gamma B7 ... 89 5e-17
AF152336-1|AAD43730.1| 929|Homo sapiens protocadherin gamma B7 ... 89 5e-17
AF152323-1|AAD43717.1| 932|Homo sapiens protocadherin gamma A3 ... 89 5e-17
BC115409-1|AAI15410.1| 694|Homo sapiens PCDHGA3 protein protein. 89 7e-17
BC115408-1|AAI15409.1| 694|Homo sapiens PCDHGA3 protein protein. 89 7e-17
AY260901-1|AAP20591.1| 819|Homo sapiens cadherin-24 variant pro... 89 7e-17
AK057922-1|BAB71613.1| 493|Homo sapiens protein ( Homo sapiens ... 89 7e-17
AF152510-1|AAD43770.1| 829|Homo sapiens protocadherin gamma A3 ... 89 7e-17
BC103928-1|AAI03929.1| 810|Homo sapiens protocadherin gamma sub... 89 9e-17
BC103927-1|AAI03928.1| 810|Homo sapiens protocadherin gamma sub... 89 9e-17
BC103926-1|AAI03927.1| 810|Homo sapiens protocadherin gamma sub... 89 9e-17
BC069064-1|AAH69064.1| 824|Homo sapiens PCDHA3 protein protein. 89 9e-17
AL834258-1|CAD38933.1| 1084|Homo sapiens hypothetical protein pr... 89 9e-17
AF152517-1|AAD43777.1| 810|Homo sapiens protocadherin gamma B1 ... 89 9e-17
AF152330-1|AAD43724.1| 927|Homo sapiens protocadherin gamma B1 ... 89 9e-17
BC033735-1|AAH33735.1| 890|Homo sapiens PCDHA5 protein protein. 88 2e-16
AF152483-1|AAD43744.1| 816|Homo sapiens protocadherin alpha 5 s... 88 2e-16
AF152313-1|AAD43707.1| 936|Homo sapiens protocadherin alpha 5 p... 88 2e-16
AC005609-9|AAC34321.1| 816|Homo sapiens KIAA0345-like 9 protein. 88 2e-16
BC031837-1|AAH31837.1| 800|Homo sapiens protocadherin beta 10 p... 87 2e-16
AY358720-1|AAQ89082.1| 800|Homo sapiens PCDHB10 protein. 87 2e-16
AF217748-1|AAK51616.1| 800|Homo sapiens protocadherin-beta10 pr... 87 2e-16
AF152489-1|AAD43750.1| 800|Homo sapiens protocadherin beta 10 p... 87 2e-16
BC132769-1|AAI32770.1| 828|Homo sapiens protocadherin gamma sub... 87 3e-16
AY358654-1|AAQ89017.1| 772|Homo sapiens CDH19 protein. 87 3e-16
AJ007607-1|CAC13126.1| 772|Homo sapiens cadherin-19 protein. 87 3e-16
AF152516-1|AAD43776.1| 828|Homo sapiens protocadherin gamma A9 ... 87 3e-16
AF152329-1|AAD43723.1| 932|Homo sapiens protocadherin gamma A9 ... 87 3e-16
BC133708-1|AAI33709.1| 693|Homo sapiens PCDHGA3 protein protein. 86 5e-16
AF152475-1|AAD43736.1| 844|Homo sapiens protocadherin alpha 10 ... 86 5e-16
AF152306-1|AAD43700.1| 948|Homo sapiens protocadherin alpha 10 ... 86 5e-16
AC005609-4|AAC34317.1| 844|Homo sapiens KIAA0345-like 4 protein. 86 5e-16
AB208927-1|BAD92164.1| 961|Homo sapiens protocadherin gamma sub... 86 5e-16
L34056-1|AAA35622.1| 796|Homo sapiens cadherin-11 protein. 86 6e-16
BC105111-1|AAI05112.1| 884|Homo sapiens protocadherin alpha sub... 86 6e-16
BC104776-1|AAI04777.1| 884|Homo sapiens protocadherin alpha sub... 86 6e-16
BC063288-1|AAH63288.1| 1007|Homo sapiens protocadherin alpha sub... 86 6e-16
BC001186-1|AAH01186.1| 795|Homo sapiens protocadherin beta 5 pr... 86 6e-16
AF217753-1|AAK51620.1| 795|Homo sapiens protocadherin-beta5 pro... 86 6e-16
AF152498-1|AAD43759.1| 795|Homo sapiens protocadherin beta 5 pr... 86 6e-16
AF152474-1|AAD43735.1| 884|Homo sapiens protocadherin alpha C2 ... 86 6e-16
AF152304-1|AAD43698.1| 1007|Homo sapiens protocadherin alpha C2 ... 86 6e-16
AF134474-1|AAP97251.1| 795|Homo sapiens protocadherin protein. 86 6e-16
AB209393-1|BAD92630.1| 796|Homo sapiens protocadherin beta 5 pr... 86 6e-16
BC130333-1|AAI30334.1| 793|Homo sapiens protocadherin beta 7 pr... 85 8e-16
BC098574-1|AAH98574.1| 793|Homo sapiens protocadherin beta 7 pr... 85 8e-16
BC003126-1|AAH03126.1| 808|Homo sapiens protocadherin alpha 2 p... 85 8e-16
AK222678-1|BAD96398.1| 793|Homo sapiens protocadherin beta 7 pr... 85 8e-16
AJ007609-1|CAC22256.1| 949|Homo sapiens protocadherin alpha 11 ... 85 8e-16
AF152480-1|AAD43741.1| 824|Homo sapiens protocadherin alpha 2 s... 85 8e-16
AF152476-1|AAD43737.1| 810|Homo sapiens protocadherin alpha 11 ... 85 8e-16
AF152310-1|AAD43704.1| 948|Homo sapiens protocadherin alpha 2 p... 85 8e-16
AF152307-1|AAD43701.1| 949|Homo sapiens protocadherin alpha 11 ... 85 8e-16
AC005609-12|AAC34324.1| 824|Homo sapiens KIAA0345-like 12 protein. 85 8e-16
AC005609-3|AAC34316.1| 810|Homo sapiens KIAA0345-like 3 protein. 85 8e-16
BC130331-1|AAI30332.1| 793|Homo sapiens protocadherin beta 7 pr... 85 1e-15
BC101038-1|AAI01039.1| 871|Homo sapiens protocadherin gamma sub... 85 1e-15
BC101036-1|AAI01037.1| 870|Homo sapiens PCDHGC4 protein protein. 85 1e-15
BC101035-1|AAI01036.1| 871|Homo sapiens protocadherin gamma sub... 85 1e-15
BC013609-1|AAH13609.1| 796|Homo sapiens cadherin 11, type 2, OB... 85 1e-15
AF217750-1|AAK51617.1| 793|Homo sapiens protocadherin-beta7 pro... 85 1e-15
AF152525-1|AAD43785.1| 871|Homo sapiens protocadherin gamma C4 ... 85 1e-15
AF152505-1|AAD43766.1| 837|Homo sapiens protocadherin gamma A11... 85 1e-15
AF152504-1|AAD43765.1| 750|Homo sapiens protocadherin gamma A11... 85 1e-15
AF152500-1|AAD43761.1| 793|Homo sapiens protocadherin beta 7 pr... 85 1e-15
AF152338-1|AAD43732.1| 938|Homo sapiens protocadherin gamma C4 ... 85 1e-15
AF152320-1|AAD43714.1| 935|Homo sapiens protocadherin gamma A11... 85 1e-15
AB035303-1|BAA87417.1| 788|Homo sapiens cadherin-10 protein. 85 1e-15
D21255-1|BAA04799.1| 693|Homo sapiens OB-cadherin-2 protein. 85 1e-15
D21254-1|BAA04798.1| 796|Homo sapiens OB-cadherin-1 protein. 85 1e-15
AK000054-1|BAA90911.1| 959|Homo sapiens protein ( Homo sapiens ... 85 1e-15
AB209760-1|BAD92997.1| 798|Homo sapiens cadherin 11, type 2 iso... 85 1e-15
AB160984-1|BAD08246.1| 1123|Homo sapiens KIAA0811 protein protein. 85 1e-15
BC098346-1|AAH98346.1| 795|Homo sapiens protocadherin beta 4 pr... 84 2e-15
BC098139-1|AAH98139.1| 795|Homo sapiens protocadherin beta 4 pr... 84 2e-15
BC051287-1|AAH51287.1| 345|Homo sapiens PCDH1 protein protein. 84 2e-15
AK222560-1|BAD96280.1| 793|Homo sapiens protocadherin beta 7 pr... 84 2e-15
AF282973-1|AAG10031.1| 610|Homo sapiens protocadherin-beta8 pro... 84 2e-15
AF217754-1|AAK51621.1| 795|Homo sapiens protocadherin-beta4 pro... 84 2e-15
AF152497-1|AAD43758.1| 795|Homo sapiens protocadherin beta 4 pr... 84 2e-15
BC098575-1|AAH98575.1| 798|Homo sapiens protocadherin beta 2 pr... 84 2e-15
BC098347-1|AAH98347.1| 798|Homo sapiens protocadherin beta 2, p... 84 2e-15
AF217756-1|AAK51623.1| 798|Homo sapiens protocadherin-beta2 pro... 84 2e-15
AF152495-1|AAD43756.1| 798|Homo sapiens protocadherin beta 2 pr... 84 2e-15
BC130447-1|AAI30448.1| 685|Homo sapiens protocadherin alpha 10 ... 83 3e-15
AF039747-1|AAD44017.1| 788|Homo sapiens cadherin-10 protein. 83 3e-15
AB209745-1|BAD92982.1| 784|Homo sapiens protocadherin beta 2 pr... 83 3e-15
BC026218-1|AAH26218.1| 934|Homo sapiens protocadherin gamma sub... 83 4e-15
BC019299-1|AAH19299.1| 934|Homo sapiens protocadherin gamma sub... 83 4e-15
AF152524-1|AAD43784.1| 863|Homo sapiens protocadherin gamma C3 ... 83 4e-15
AF152337-1|AAD43731.1| 934|Homo sapiens protocadherin gamma C3 ... 83 4e-15
AF052685-1|AAC08350.1| 934|Homo sapiens protocadherin 43 protein. 83 4e-15
AB074170-1|BAE45735.1| 348|Homo sapiens putative protein produc... 83 4e-15
AF169689-1|AAF89329.1| 685|Homo sapiens protocadherin alpha 10 ... 83 6e-15
BC052973-1|AAH52973.1| 1187|Homo sapiens PCDH12 protein protein. 82 1e-14
BC042634-1|AAH42634.1| 1187|Homo sapiens PCDH12 protein protein. 82 1e-14
AY358428-1|AAQ88794.1| 1184|Homo sapiens PCDH12 protein. 82 1e-14
AK024140-1|BAB14837.1| 1187|Homo sapiens protein ( Homo sapiens ... 82 1e-14
AF240635-1|AAF73962.1| 1184|Homo sapiens vascular endothelial ca... 82 1e-14
AF231025-1|AAF61931.1| 1184|Homo sapiens protocadherin 12 protein. 82 1e-14
AF152513-1|AAD43773.1| 818|Homo sapiens protocadherin gamma A6 ... 82 1e-14
AF152501-1|AAD43762.2| 801|Homo sapiens protocadherin beta 8 pr... 82 1e-14
AF152326-1|AAD43720.1| 932|Homo sapiens protocadherin gamma A6 ... 82 1e-14
AB209178-1|BAD92415.1| 950|Homo sapiens protocadherin gamma sub... 82 1e-14
AB026893-1|BAA95162.1| 1184|Homo sapiens vascular cadherin-2 pro... 82 1e-14
BC113745-1|AAI13746.1| 789|Homo sapiens cadherin 9, type 2, pre... 81 1e-14
BC107594-1|AAI07595.1| 789|Homo sapiens cadherin 9, type 2 (T1-... 81 1e-14
AK127704-1|BAC87093.1| 1366|Homo sapiens protein ( Homo sapiens ... 81 1e-14
AB035302-1|BAA87416.1| 789|Homo sapiens cadherin-9 protein. 81 1e-14
AK027282-1|BAB55016.1| 390|Homo sapiens protein ( Homo sapiens ... 81 2e-14
AC079298-1|AAY41019.1| 959|Homo sapiens unknown protein. 81 2e-14
BC015877-1|AAH15877.1| 390|Homo sapiens CDH19 protein protein. 81 2e-14
AF169695-1|AAF89692.1| 686|Homo sapiens protocadherin alpha 1 a... 81 2e-14
AF152479-1|AAD43740.1| 807|Homo sapiens protocadherin alpha 1 s... 81 2e-14
AF152305-1|AAD43699.1| 950|Homo sapiens protocadherin alpha 1 p... 81 2e-14
AC005609-13|AAC34325.1| 807|Homo sapiens KIAA0345-like 13 protein. 81 2e-14
BC104817-1|AAI04818.1| 796|Homo sapiens protocadherin beta 3 pr... 79 5e-14
AJ564963-1|CAD92434.1| 787|Homo sapiens protocadherin protein. 79 5e-14
AJ564962-1|CAD92433.1| 762|Homo sapiens protocadherin protein. 79 5e-14
AJ564961-1|CAD92432.1| 841|Homo sapiens protocadherin protein. 79 5e-14
AJ564960-1|CAD92431.1| 831|Homo sapiens protocadherin protein. 79 5e-14
AJ276803-1|CAC13122.1| 1037|Homo sapiens protocadherin protein. 79 5e-14
AF332217-1|AAK13469.1| 1340|Homo sapiens protocadherin 11 protein. 79 5e-14
AF332216-1|AAK13468.1| 1048|Homo sapiens protocadherin 11 protein. 79 5e-14
AF277053-1|AAL55729.1| 1037|Homo sapiens protocadherin-PC protein. 79 5e-14
AF217743-1|AAK51611.1| 734|Homo sapiens protocadherin-psi2 prot... 79 5e-14
AF217755-1|AAK51622.1| 796|Homo sapiens protocadherin-beta3 pro... 79 7e-14
AF169691-1|AAF89688.1| 398|Homo sapiens cadherin-like protein V... 79 7e-14
AF152496-1|AAD43757.1| 796|Homo sapiens protocadherin beta 3 pr... 79 7e-14
AB006757-1|BAA25196.1| 1200|Homo sapiens PCDH7 (BH-Pcdh)c protein. 79 7e-14
AB006756-1|BAA25195.1| 1072|Homo sapiens PCDH7 (BH-Pcdh)b protein. 79 7e-14
AB006755-1|BAA25194.1| 1069|Homo sapiens PCDH7 (BH-Pcdh)a protein. 79 7e-14
BC111560-1|AAI11561.1| 1040|Homo sapiens protocadherin 10 protein. 79 9e-14
BC038797-1|AAH38797.1| 787|Homo sapiens protocadherin beta 15 p... 79 9e-14
AY861435-1|AAX56125.1| 1065|Homo sapiens protocadherin 11X isofo... 79 9e-14
AY861434-1|AAX56124.1| 1329|Homo sapiens protocadherin 11X isofo... 79 9e-14
AY861433-1|AAX56123.1| 1310|Homo sapiens protocadherin 11X isofo... 79 9e-14
AY861432-1|AAX56122.1| 1339|Homo sapiens protocadherin 11X isofo... 79 9e-14
AL133321-2|CAI41436.1| 1337|Homo sapiens protocadherin 11 X-link... 79 9e-14
AL133321-1|CAI41435.1| 1347|Homo sapiens protocadherin 11 X-link... 79 9e-14
AL133274-3|CAI41629.1| 1310|Homo sapiens protocadherin 11 X-link... 79 9e-14
AL133274-2|CAI41631.1| 1337|Homo sapiens protocadherin 11 X-link... 79 9e-14
AL133274-1|CAI41630.1| 1347|Homo sapiens protocadherin 11 X-link... 79 9e-14
AL121869-5|CAI41414.1| 1337|Homo sapiens protocadherin 11 X-link... 79 9e-14
AL121869-4|CAI41413.1| 1347|Homo sapiens protocadherin 11 X-link... 79 9e-14
AL121869-3|CAI41412.1| 1310|Homo sapiens protocadherin 11 X-link... 79 9e-14
AJ276804-1|CAC13123.1| 1025|Homo sapiens protocadherin protein. 79 9e-14
AF332219-1|AAK13471.1| 1337|Homo sapiens protocadherin 11 protein. 79 9e-14
AF332218-1|AAK13470.1| 1347|Homo sapiens protocadherin 11 protein. 79 9e-14
AF217742-1|AAK51610.1| 787|Homo sapiens protocadherin-beta15 pr... 79 9e-14
AF152494-1|AAD43755.1| 787|Homo sapiens protocadherin beta 15 p... 79 9e-14
AB026187-1|BAA90765.1| 1021|Homo sapiens protocadherin-Xa protein. 79 9e-14
BC112098-1|AAI12099.1| 818|Homo sapiens protocadherin beta 1, p... 78 1e-13
BC112096-1|AAI12097.1| 818|Homo sapiens protocadherin beta 1, p... 78 1e-13
AL109928-5|CAD55557.2| 832|Homo sapiens cadherin-like 26 protein. 78 1e-13
AK021915-1|BAB13935.1| 744|Homo sapiens protein ( Homo sapiens ... 78 1e-13
AF152488-1|AAD43749.1| 818|Homo sapiens protocadherin beta 1 pr... 78 1e-13
AY013874-1|AAK21987.1| 896|Homo sapiens protocadherin 10 protein. 77 2e-13
AC105383-1|AAY41018.1| 1040|Homo sapiens unknown protein. 77 2e-13
AB037821-1|BAA92638.1| 1093|Homo sapiens KIAA1400 protein protein. 77 2e-13
BC139903-1|AAI39904.1| 406|Homo sapiens Unknown (protein for MG... 77 3e-13
BC101049-1|AAI01050.1| 801|Homo sapiens cadherin 20, type 2 pro... 77 3e-13
BC101048-1|AAI01049.1| 801|Homo sapiens cadherin 20, type 2 pro... 77 3e-13
BC101047-1|AAI01048.1| 801|Homo sapiens cadherin 20, type 2 pro... 77 3e-13
AL731541-3|CAI40838.1| 728|Homo sapiens cadherin-like 23 protein. 77 3e-13
AF217289-1|AAG23739.1| 801|Homo sapiens cadherin 20 protein. 77 3e-13
AB058715-1|BAB47441.1| 803|Homo sapiens KIAA1812 protein protein. 77 3e-13
L11373-1|AAA75391.1| 904|Homo sapiens protocadherin 43 protein. 77 4e-13
AJ564936-1|CAD92415.1| 787|Homo sapiens protocadherin protein. 76 5e-13
AJ564935-1|CAD92414.1| 762|Homo sapiens protocadherin protein. 76 5e-13
AJ564934-1|CAD92413.1| 841|Homo sapiens protocadherin protein. 76 5e-13
AJ564933-1|CAD92412.1| 831|Homo sapiens protocadherin protein. 76 5e-13
AF217288-1|AAK82656.1| 1310|Homo sapiens protocadherin-S protein. 76 5e-13
AF206516-1|AAK82655.1| 1347|Homo sapiens protocadherin-S protein. 76 5e-13
AF152522-1|AAD43782.1| 820|Homo sapiens protocadherin gamma B6 ... 76 5e-13
AF152335-1|AAD43729.1| 930|Homo sapiens protocadherin gamma B6 ... 76 5e-13
AF152511-1|AAD43771.1| 820|Homo sapiens protocadherin gamma A4 ... 76 6e-13
AF152324-1|AAD43718.1| 931|Homo sapiens protocadherin gamma A4 ... 76 6e-13
BC038405-1|AAH38405.1| 651|Homo sapiens mucin and cadherin-like... 75 1e-12
AL834254-1|CAD38929.1| 647|Homo sapiens hypothetical protein pr... 75 1e-12
AF131761-1|AAD20038.1| 420|Homo sapiens Similar to protocadheri... 75 1e-12
BC093815-1|AAH93815.1| 1135|Homo sapiens protocadherin 18 protein. 74 2e-12
AY358368-1|AAQ88734.1| 839|Homo sapiens MUCDHL protein. 74 2e-12
AK000384-1|BAA91130.1| 651|Homo sapiens protein ( Homo sapiens ... 74 2e-12
AF301909-1|AAG33495.1| 845|Homo sapiens mu-protocadherin protein. 74 2e-12
AF276242-1|AAG30821.1| 651|Homo sapiens mu-protocadherin relate... 74 2e-12
AF258676-1|AAG16733.1| 845|Homo sapiens MUCDHL-FL protein. 74 2e-12
AF258674-2|AAG16731.1| 845|Homo sapiens MUCDHL-FL protein. 74 2e-12
AF217751-1|AAK51618.1| 587|Homo sapiens protocadherin-psi1 prot... 74 2e-12
AB046782-1|BAB13388.1| 1136|Homo sapiens KIAA1562 protein protein. 74 2e-12
AY029237-1|AAK31804.1| 1955|Homo sapiens protocadherin 15 protein. 73 5e-12
AL365496-10|CAM19874.1| 1957|Homo sapiens protocadherin 15 protein. 73 5e-12
AL365496-9|CAH73916.1| 1955|Homo sapiens protocadherin 15 protein. 73 5e-12
AL365496-8|CAM19873.1| 1952|Homo sapiens protocadherin 15 protein. 73 5e-12
AL365496-7|CAM19872.1| 1932|Homo sapiens protocadherin 15 protein. 73 5e-12
AL365496-4|CAM19869.1| 1539|Homo sapiens protocadherin 15 protein. 73 5e-12
AL365496-3|CAM19868.1| 1785|Homo sapiens protocadherin 15 protein. 73 5e-12
AL365496-1|CAM19866.1| 1684|Homo sapiens protocadherin 15 protein. 73 5e-12
AL360214-13|CAM21544.1| 1932|Homo sapiens protocadherin 15 protein. 73 5e-12
AL360214-12|CAM21543.1| 1952|Homo sapiens protocadherin 15 protein. 73 5e-12
AL360214-11|CAM21542.1| 1957|Homo sapiens protocadherin 15 protein. 73 5e-12
AL360214-10|CAI15201.1| 1955|Homo sapiens protocadherin 15 protein. 73 5e-12
AL360214-6|CAM21538.1| 1785|Homo sapiens protocadherin 15 protein. 73 5e-12
AL360214-5|CAM21537.1| 1539|Homo sapiens protocadherin 15 protein. 73 5e-12
AL360214-4|CAM21536.1| 1684|Homo sapiens protocadherin 15 protein. 73 5e-12
AL356114-13|CAH71769.1| 1955|Homo sapiens protocadherin 15 protein. 73 5e-12
AL356114-12|CAM15125.1| 1932|Homo sapiens protocadherin 15 protein. 73 5e-12
AL356114-11|CAM15124.1| 1957|Homo sapiens protocadherin 15 protein. 73 5e-12
AL356114-10|CAM15123.1| 1952|Homo sapiens protocadherin 15 protein. 73 5e-12
AL356114-7|CAM15120.1| 1539|Homo sapiens protocadherin 15 protein. 73 5e-12
AL356114-6|CAM15119.1| 1785|Homo sapiens protocadherin 15 protein. 73 5e-12
AL356114-4|CAM15117.1| 1684|Homo sapiens protocadherin 15 protein. 73 5e-12
AL353784-11|CAM16792.1| 1957|Homo sapiens protocadherin 15 protein. 73 5e-12
AL353784-10|CAH72390.1| 1955|Homo sapiens protocadherin 15 protein. 73 5e-12
AL353784-9|CAM16791.1| 1952|Homo sapiens protocadherin 15 protein. 73 5e-12
AL353784-7|CAM16789.1| 1785|Homo sapiens protocadherin 15 protein. 73 5e-12
AL353784-5|CAM16787.1| 1539|Homo sapiens protocadherin 15 protein. 73 5e-12
AL353784-3|CAM16785.1| 1684|Homo sapiens protocadherin 15 protein. 73 5e-12
AF029343-1|AAB84144.1| 889|Homo sapiens protocadherin 68 protein. 73 5e-12
BC028165-1|AAH28165.1| 1159|Homo sapiens protocadherin 17 protein. 73 6e-12
AY029205-1|AAK31581.1| 1955|Homo sapiens protocadherin 15 protein. 73 6e-12
AL445288-1|CAI17092.1| 1159|Homo sapiens protocadherin 17 protein. 73 6e-12
AL445216-1|CAH71250.1| 1159|Homo sapiens protocadherin 17 protein. 73 6e-12
BC042650-1|AAH42650.1| 605|Homo sapiens PCDHGC3 protein protein. 72 8e-12
X79981-1|CAA56306.1| 784|Homo sapiens VE-cadherin protein. 72 1e-11
X59796-1|CAA42468.1| 780|Homo sapiens cadherin-5 protein. 72 1e-11
U84722-1|AAB41796.1| 784|Homo sapiens vascular endothelial cadh... 72 1e-11
AB209908-1|BAD93145.1| 807|Homo sapiens cadherin 5, type 2 prep... 72 1e-11
AB035304-1|BAA87418.1| 784|Homo sapiens cadherin-5 protein. 72 1e-11
BC117520-1|AAI17521.1| 669|Homo sapiens CDH5 protein protein. 70 3e-11
BC096365-1|AAH96365.1| 662|Homo sapiens CDH5 protein protein. 70 3e-11
BC096364-1|AAH96364.3| 669|Homo sapiens CDH5 protein protein. 70 3e-11
BC096363-1|AAH96363.1| 669|Homo sapiens CDH5 protein protein. 70 3e-11
BC036025-1|AAH36025.1| 1070|Homo sapiens protocadherin 8 protein. 70 3e-11
AL139085-5|CAI14111.1| 973|Homo sapiens protocadherin 8 protein. 70 3e-11
AL139085-4|CAI14110.1| 1070|Homo sapiens protocadherin 8 protein. 70 3e-11
AF061573-1|AAC70009.2| 1070|Homo sapiens protocadherin protein. 70 3e-11
AY013873-1|AAK21986.1| 973|Homo sapiens protocadherin ARCADLIN ... 69 1e-10
AF169693-1|AAF89690.1| 947|Homo sapiens protocadherin 13 protein. 68 2e-10
AF258675-1|AAG16732.1| 487|Homo sapiens MUCDHL-ALT protein. 67 2e-10
AF258674-1|AAG16730.1| 487|Homo sapiens MUCDHL-ALT protein. 67 2e-10
BC027907-1|AAH27907.1| 924|Homo sapiens protocadherin 20 protein. 67 3e-10
AL592490-1|CAH73802.2| 924|Homo sapiens protocadherin 20 protein. 67 3e-10
AL122081-1|CAB59256.1| 373|Homo sapiens hypothetical protein pr... 66 4e-10
AL360214-3|CAI15200.1| 961|Homo sapiens protocadherin 15 protein. 66 5e-10
AL356114-3|CAH71768.1| 961|Homo sapiens protocadherin 15 protein. 66 5e-10
AL353784-2|CAH72389.1| 961|Homo sapiens protocadherin 15 protein. 66 5e-10
AK074160-1|BAB84986.1| 535|Homo sapiens FLJ00233 protein protein. 64 2e-09
AB209205-1|BAD92442.1| 430|Homo sapiens protocadherin alpha 6 i... 64 2e-09
AK093818-1|BAC04231.1| 455|Homo sapiens protein ( Homo sapiens ... 62 9e-09
AL365496-6|CAM19871.1| 981|Homo sapiens protocadherin 15 protein. 62 1e-08
AL360214-7|CAM21539.1| 981|Homo sapiens protocadherin 15 protein. 62 1e-08
AL360214-1|CAM21534.1| 718|Homo sapiens protocadherin 15 protein. 62 1e-08
AL356114-8|CAM15121.1| 981|Homo sapiens protocadherin 15 protein. 62 1e-08
AL356114-1|CAM15115.1| 718|Homo sapiens protocadherin 15 protein. 62 1e-08
AL353784-6|CAM16788.1| 981|Homo sapiens protocadherin 15 protein. 62 1e-08
X83228-1|CAA58231.1| 832|Homo sapiens LI-cadherin protein. 61 2e-08
X83929-1|CAA58781.1| 896|Homo sapiens desmocollin type 3 protein. 60 3e-08
S42303-1|AAB22854.1| 905|Homo sapiens N-cadherin protein. 60 3e-08
M34064-1|AAA03236.1| 747|Homo sapiens NCAD protein. 60 3e-08
D17427-1|BAA04249.1| 896|Homo sapiens desmocollin type 4 protein. 60 3e-08
AF293359-2|AAG23427.1| 839|Homo sapiens desmocollin 3b protein. 60 3e-08
AF293359-1|AAG23426.1| 896|Homo sapiens desmocollin 3a protein. 60 3e-08
U07969-1|AAA19021.1| 832|Homo sapiens intestinal peptide-associ... 60 5e-08
BC113464-1|AAI13465.1| 832|Homo sapiens cadherin 17, LI cadheri... 60 5e-08
BC112150-1|AAI12151.1| 916|Homo sapiens cadherin 4, type 1, pre... 60 5e-08
BC112013-1|AAI12014.1| 832|Homo sapiens cadherin 17, precursor ... 60 5e-08
BC101651-1|AAI01652.1| 916|Homo sapiens cadherin 4, type 1, R-c... 60 5e-08
AL365401-1|CAC26840.2| 916|Homo sapiens cadherin 4, type 1, R-c... 60 5e-08
AL365229-1|CAI16510.1| 916|Homo sapiens cadherin 4, type 1, R-c... 60 5e-08
AL162457-1|CAH73749.1| 916|Homo sapiens cadherin 4, type 1, R-c... 60 5e-08
AL109911-1|CAI19181.1| 916|Homo sapiens cadherin 4, type 1, R-c... 60 5e-08
AK091496-1|BAC03677.1| 824|Homo sapiens protein ( Homo sapiens ... 60 5e-08
X54315-1|CAA38213.1| 906|Homo sapiens protein ( Human mRNA for ... 59 6e-08
BC030653-1|AAH30653.1| 713|Homo sapiens cadherin 13, H-cadherin... 59 6e-08
BC028624-1|AAH28624.1| 713|Homo sapiens cadherin 13, H-cadherin... 59 6e-08
AK000226-1|BAA91021.1| 651|Homo sapiens protein ( Homo sapiens ... 59 6e-08
Z35402-1|CAA84586.1| 827|Homo sapiens E-cadherin protein. 59 8e-08
Z18923-1|CAA79356.1| 882|Homo sapiens E-cadherin protein. 59 8e-08
Z13009-1|CAA78353.1| 882|Homo sapiens E-cadherin protein. 59 8e-08
DQ090940-1|AAY68225.1| 882|Homo sapiens cadherin 1, type 1, E-c... 59 8e-08
BC141838-1|AAI41839.1| 647|Homo sapiens Unknown (protein for MG... 59 8e-08
U59289-1|AAB18912.1| 713|Homo sapiens H-cadherin protein. 58 1e-07
U59288-1|AAB18911.1| 713|Homo sapiens H-cadherin protein. 58 1e-07
L34058-1|AAA35624.1| 713|Homo sapiens cadherin-13 protein. 58 1e-07
L08599-1|AAA61259.1| 878|Homo sapiens uvomorulin protein. 58 1e-07
BC038799-1|AAH38799.1| 745|Homo sapiens PCDH21 protein protein. 58 1e-07
AB053448-1|BAB61905.1| 858|Homo sapiens KIAA1775 protein protein. 58 1e-07
AB001103-1|BAA32411.1| 713|Homo sapiens H-cadherin protein. 58 1e-07
AL137471-1|CAB70755.1| 709|Homo sapiens hypothetical protein pr... 58 2e-07
Z34522-2|CAA84279.1| 894|Homo sapiens Dsc1b precursor protein. 57 2e-07
Z34522-1|CAA84278.1| 840|Homo sapiens Dsc1a precursor protein. 57 2e-07
X72925-2|CAA51429.1| 829|Homo sapiens Dsc1a precursor protein. 57 2e-07
X72925-1|CAA51428.1| 840|Homo sapiens Dsc1b precursor protein. 57 2e-07
BC109240-1|AAI09241.1| 269|Homo sapiens IL19 protein protein. 57 2e-07
BC036470-1|AAH36470.1| 906|Homo sapiens cadherin 2, type 1, N-c... 57 2e-07
AF293358-2|AAG23425.1| 840|Homo sapiens desmocollin 1b protein. 57 2e-07
AF293358-1|AAG23424.1| 894|Homo sapiens desmocollin 1a protein. 57 2e-07
L34059-1|AAA35627.1| 916|Homo sapiens cadherin-4 protein. 57 3e-07
AB047004-1|BAB40777.1| 1310|Homo sapiens protocadherin LKC protein. 57 3e-07
X63629-1|CAA45177.1| 829|Homo sapiens p-cadherin protein. 56 4e-07
BC014462-1|AAH14462.1| 784|Homo sapiens CDH3 protein protein. 56 4e-07
AY354498-1|AAR10444.1| 702|Homo sapiens protocadherin protein p... 56 4e-07
BC130282-1|AAI30283.1| 1310|Homo sapiens PCLKC protein protein. 56 6e-07
AB000895-1|BAA21133.1| 137|Homo sapiens cadherin FIB1 protein. 56 6e-07
BC041846-1|AAH41846.1| 829|Homo sapiens cadherin 3, type 1, P-c... 56 7e-07
AK023785-1|BAB14677.1| 808|Homo sapiens protein ( Homo sapiens ... 56 7e-07
BC108254-1|AAI08255.1| 445|Homo sapiens CDH23 protein protein. 55 1e-06
BC027912-1|AAH27912.1| 829|Homo sapiens cadherin 16, KSP-cadher... 54 3e-06
AY358911-1|AAQ89270.1| 807|Homo sapiens Ksp-cadherin protein. 54 3e-06
AF016272-1|AAC34255.1| 829|Homo sapiens Ksp-cadherin protein. 54 3e-06
AB000896-1|BAA21134.1| 141|Homo sapiens cadherin FIB2 protein. 52 7e-06
X57548-1|CAA40773.1| 748|Homo sapiens N-cadherin protein. 52 9e-06
X56807-2|CAA40142.1| 914|Homo sapiens desmocollin type 2b protein. 51 2e-05
X56807-1|CAA40141.1| 860|Homo sapiens desmocollin type 2a protein. 51 2e-05
BC063291-1|AAH63291.1| 901|Homo sapiens desmocollin 2 protein. 51 2e-05
AF135156-1|AAG43278.1| 260|Homo sapiens D-cadherin precursor pr... 51 2e-05
AL365496-2|CAM19867.1| 719|Homo sapiens protocadherin 15 protein. 50 4e-05
AL360214-8|CAM21540.1| 719|Homo sapiens protocadherin 15 protein. 50 4e-05
AL356114-9|CAM15122.1| 719|Homo sapiens protocadherin 15 protein. 50 4e-05
AL353784-4|CAM16786.1| 719|Homo sapiens protocadherin 15 protein. 50 4e-05
BC016722-1|AAH16722.1| 230|Homo sapiens FAT3 protein protein. 50 5e-05
AL365496-5|CAM19870.1| 650|Homo sapiens protocadherin 15 protein. 50 5e-05
>X87241-1|CAA60685.1| 4590|Homo sapiens homologue of Drosophila Fat
protein protein.
Length = 4590
Score = 130 bits (314), Expect = 2e-29
Identities = 134/512 (26%), Positives = 209/512 (40%), Gaps = 27/512 (5%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAA-VGIVPGSKNLTLLRALDREEKI 69
I ED G +I +S +IT L GA + P + L LDREE+
Sbjct: 3034 IPEDVLPGKLIMQISATDADIRSNAEITYTLLGSGAEKFKLNPDTGELKTSTPLDREEQ- 3092
Query: 70 GPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXX 129
++ V R S V+ + DVNDNAP++ PYA+ V E
Sbjct: 3093 AVYHLLVRATDGGGRFCQASIVVTLE----DVNDNAPEFSADPYAITVFENTEPGTLLTR 3148
Query: 130 XXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQD 189
+D D G + + Y+++ ++ NEL II ++KPLD E +T+ L+ D
Sbjct: 3149 VQATDADA-GLNRKILYSLIDSADGQFS--INELSGIIQLEKPLDRELQAVYTLSLKAVD 3205
Query: 190 QGSPPLYSDT-TLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDL 248
QG P + T T+ V+VLD +D P F Y Y A + +D GT + + AA +D+
Sbjct: 3206 QGLPRRLTATGTVIVSVLDINDNPPVFEYREYGATVSEDILVGTEVL----QVYAASRDI 3261
Query: 249 GINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALA 307
NA + YS +G+ ++ TG V + L E + ++AT P +A
Sbjct: 3262 EANAEITYSIISGNEHGKFSIDSKTGAVFIIENLDYESSHEYYLTVEATDGGTPSLSDVA 3321
Query: 308 TLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFY 367
T+ F+Q Y+T +SE A ++T+ + S + +
Sbjct: 3322 TVNVNVTDINDNTPV-----FSQDTYTTVISEDAVLEQSVITVMADDADGP-SNSHIHYS 3375
Query: 368 VSDRSFLDKFAINNA-GEVILRRSLDYETTSNYFYQVMVTDSISN---DTASINISVEDV 423
+ D + F I+ GEV + + LD ET S Y V +D+ S +T ++NI V DV
Sbjct: 3376 IIDGNQGSSFTIDPVRGEVKVTKLLDRETISGYTLTVQASDNGSPPRVNTTTVNIDVSDV 3435
Query: 424 NEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGDAGTLALSLAGQHARMFYIN 483
N+ P F Y +H+G + + G + F +N
Sbjct: 3436 NDNAPVFSRGNYSVIIQENKPVGFSVLQLVVTDEDSSHNGPPFFFTI-VTGNDEKAFEVN 3494
Query: 484 ASGDLFLREEAIGNLNSSSLHLVATAIDSGIP 515
G + L AI L D+G P
Sbjct: 3495 PQG-VLLTSSAIKRKEKDHYLLQVKVADNGKP 3525
Score = 124 bits (298), Expect = 2e-27
Identities = 103/437 (23%), Positives = 178/437 (40%), Gaps = 18/437 (4%)
Query: 6 VESFFISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDR 65
VE + ED P+GS++ T+S + + + G+I +++ G+ VG+ + ++ DR
Sbjct: 1038 VEKGTVKEDAPVGSLVMTVSAHDEDAGRDGEIRYSIRD-GSGVGVFKIGEETGVIETSDR 1096
Query: 66 EEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXX 125
++ S+ ++ V + S I + + V DVNDNAPQ Y + E
Sbjct: 1097 LDRESTSHYWLTVFATDQGVVPLSSFIEIYIEVEDVNDNAPQTSEPVYYPEIMENSPKDV 1156
Query: 126 XXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKL 185
D D + L Y + G + + I + LD E + +++
Sbjct: 1157 SVVQIEAFDPDSSS-NDKLMYKITSGNPQGFFSIHPKTGLITTTSRKLDREQQDEHILEV 1215
Query: 186 RVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGP---IS 242
V D GSPP + + V +LD +D P+F + Y LP+ + P +
Sbjct: 1216 TVTDNGSPPKSTIARVIVKILDENDNKPQFLQKFYKIRLPEREKPDRERNARREPLYRVI 1275
Query: 243 AADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATK-QLIAELDPSVTIVLKATQVDN 300
A D+D G NA + YS G+ + TG V++ + E D +L VDN
Sbjct: 1276 ATDKDEGPNAEISYSIEDGNEHGKFFIEPKTGVVSSKRFSAAGEYD-----ILSIKAVDN 1330
Query: 301 PDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFR 360
+T + F + ++ TV E ++ ++ P
Sbjct: 1331 GRPQKSSTTRLHIEWISKPKQSLEPISFEESFFTFTVMESDPVAHMIGVISVEPPGI--- 1387
Query: 361 ESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTDSISNDTASINIS 419
PL F ++ ++ F ++ G +I+ + LD E SNY V TD + + I
Sbjct: 1388 --PLWFDITGGNYDSHFDVDKGTGTIIVAKPLDAEQKSNYNLTVEATDGTTTILTQVFIK 1445
Query: 420 VEDVNEWEPRFRHPQYE 436
V D N+ P+F +YE
Sbjct: 1446 VIDTNDHRPQFSTSKYE 1462
Score = 105 bits (252), Expect = 7e-22
Identities = 118/518 (22%), Positives = 206/518 (39%), Gaps = 33/518 (6%)
Query: 10 FISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNL-----TLLRALD 64
FI E+ P GS + + + S G + L + + I + N+ T L+ LD
Sbjct: 2819 FIVENLPGGSRVIQIRASDADSGTNGQVMYSLDQSQSVEVIESFAINMETGWITTLKELD 2878
Query: 65 REEKIGPSNVYVNV-RCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXX 123
E++ N + V D S V V V DVND+ P++ Y VSE
Sbjct: 2879 HEKR---DNYQIKVVASDHGEKIQLSSTAIVDVTVTDVNDSPPRFTAEIYKGTVSEDDPQ 2935
Query: 124 XXXXXXXXXSDRDQPGPHSALHYAVLPG-PHSEYLGFENELEPIIVVKKPLDFETVNNFT 182
+D D + + Y + G P ++ + E + VKKPLD E +N+
Sbjct: 2936 GGVIAILSTTDADSEEINRQVTYFITGGDPLGQFAVETIQNEWKVYVKKPLDREKRDNYL 2995
Query: 183 IKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPIS 242
+ + D G+ S ++V VLDA+D +P Y+ +P+D G + IS
Sbjct: 2996 LTITATD-GT--FSSKAIVEVKVLDANDNSPVCEKTLYSDTIPEDVLPGKLIM----QIS 3048
Query: 243 AADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPD 302
A D D+ NA + Y+ G + +N DTG++ + L E ++++AT D
Sbjct: 3049 ATDADIRSNAEITYTLLGSGAEKFKLNPDTGELKTSTPLDREEQAVYHLLVRAT--DGGG 3106
Query: 303 RYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRES 362
R+ A++ +F+ Y+ TV E PG++L + +
Sbjct: 3107 RFCQASIVVTLEDVNDNAP-----EFSADPYAITVFENTEPGTLLTRVQATDADAGLNRK 3161
Query: 363 PLQFYVSDRSFLDKFAINN-AGEVILRRSLDYETTSNYFYQVMVTDS----ISNDTASIN 417
L + +F+IN +G + L + LD E + Y + D T ++
Sbjct: 3162 ILYSLIDSAD--GQFSINELSGIIQLEKPLDRELQAVYTLSLKAVDQGLPRRLTATGTVI 3219
Query: 418 ISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGDAGTLALSLAGQHA 477
+SV D+N+ P F + +Y + + + T ++ +H
Sbjct: 3220 VSVLDINDNPPVFEYREYGATVSEDILVGTEVLQVYAASRDIEANAEI-TYSIISGNEHG 3278
Query: 478 RMFYINASGDLFLREEAIGNLNSSSLHLVATAIDSGIP 515
+ + +G +F+ E + +S +L A D G P
Sbjct: 3279 KFSIDSKTGAVFIIEN-LDYESSHEYYLTVEATDGGTP 3315
Score = 101 bits (242), Expect = 1e-20
Identities = 89/346 (25%), Positives = 155/346 (44%), Gaps = 17/346 (4%)
Query: 96 VRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSE 155
V V D NDN P++ Y V VSE +D+D GP+ + Y++L +
Sbjct: 810 VVVVDANDNPPEFLQESYFVEVSEDKEVHSEIIQVEATDKDL-GPNGHVTYSILTDTDTF 868
Query: 156 YLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQG--SPPLYSDTTLQVTVLDADDQNP 213
+ + + ++ + +PLD E + ++K+ +DQ P L+S ++V++ D +D P
Sbjct: 869 SI---DSVTGVVNIARPLDRELQHEHSLKIEARDQAREEPQLFSTVVVKVSLEDVNDNPP 925
Query: 214 KFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTG 273
F +Y + +D EGT + + A D DLG + ++YS + V+K +G
Sbjct: 926 TFIPPNYRVKVREDLPEGTVIMW----LEAHDPDLGQSGQVRYSLLDHGEGNFDVDKLSG 981
Query: 274 QVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQY 333
V +QL E + ++A P +L++ F+
Sbjct: 982 AVRIVQQLDFEKKQVYNLTVRAKDKGKP--VSLSSTCYVEVEVVDVNENLHPPVFSSFVE 1039
Query: 334 STTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAI-NNAGEVILRRSLD 392
TV E A GS+++T++ ++ R+ +++ + D S + F I G + LD
Sbjct: 1040 KGTVKEDAPVGSLVMTVSAHDEDAG-RDGEIRYSIRDGSGVGVFKIGEETGVIETSDRLD 1098
Query: 393 YETTSNYFYQVMVTDSISNDTAS---INISVEDVNEWEPRFRHPQY 435
E+TS+Y+ V TD +S I I VEDVN+ P+ P Y
Sbjct: 1099 RESTSHYWLTVFATDQGVVPLSSFIEIYIEVEDVNDNAPQTSEPVY 1144
Score = 95.5 bits (227), Expect = 7e-19
Identities = 107/441 (24%), Positives = 185/441 (41%), Gaps = 39/441 (8%)
Query: 7 ESFF---ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRAL 63
ESFF + E P+ +IG +SV DIT + V G+ + + + L
Sbjct: 1360 ESFFTFTVMESDPVAHMIGVISVEPPGIPLWFDITGGNYDSHFDVD--KGTGTIIVAKPL 1417
Query: 64 DREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXX 123
D E+K SN + V TT + V ++V D ND+ PQ+ + Y V + E
Sbjct: 1418 DAEQK---SNYNLTVEATDGTTT---ILTQVFIKVIDTNDHRPQFSTSKYEVVIPEDTAP 1471
Query: 124 XXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPI---IVVKKPLDFETVNN 180
D+D+ + L Y L + L+P + + LD E V+
Sbjct: 1472 ETEILQISAVDQDE---KNKLIY-TLQSSRDPLSLKKFRLDPATGSLYTSEKLDHEAVSP 1527
Query: 181 FTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGP 240
+ + V+DQ P + + V V D +D P FT Y + + A G+ +
Sbjct: 1528 AHLTVMVRDQDVPVKRNFARIVVNVSDTNDHAPWFTASSYKGRVYESAAVGSVVL----Q 1583
Query: 241 ISAADQDLGINAPLQYS----STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKAT 296
++A D+D G NA + YS + G+ +++ G + K+L +++KAT
Sbjct: 1584 VTALDKDKGKNAEVLYSIESGNIGNIGNSFMIDPVLGSIKTAKELDRSNQAEYDLMVKAT 1643
Query: 297 QVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQN 356
+P + ++ +FT K+YS +SE S GS V
Sbjct: 1644 DKGSPPMSEITSVRIFVTIADNASP-----KFTSKEYSVELSETVSIGSF------VGMV 1692
Query: 357 TEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTDSISNDT-A 414
T +S + + + D + D F IN ++G +I +++LD+ET Y + T+ T
Sbjct: 1693 TAHSQSSVVYEIKDGNTGDAFDINPHSGTIITQKALDFETLPIYTLIIQGTNMAGLSTNT 1752
Query: 415 SINISVEDVNEWEPRFRHPQY 435
++ + ++D N+ P F +Y
Sbjct: 1753 TVLVHLQDENDNAPVFMQAEY 1773
Score = 95.5 bits (227), Expect = 7e-19
Identities = 75/334 (22%), Positives = 139/334 (41%), Gaps = 13/334 (3%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
V V V D+NDN P +E Y VSE + RD ++ + Y+++ G
Sbjct: 3218 VIVSVLDINDNPPVFEYREYGATVSEDILVGTEVLQVYAASRDIEA-NAEITYSIISGNE 3276
Query: 154 SEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNP 213
+++ + +++ LD+E+ + + + + D G+P L T+ V V D +D P
Sbjct: 3277 HGKFSIDSKTGAVFIIEN-LDYESSHEYYLTVEATDGGTPSLSDVATVNVNVTDINDNTP 3335
Query: 214 KFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYS-STGDHKQLIVVNKDT 272
F+ + YT ++ +DA L S + A D D N+ + YS G+ ++
Sbjct: 3336 VFSQDTYTTVISEDA----VLEQSVITVMADDADGPSNSHIHYSIIDGNQGSSFTIDPVR 3391
Query: 273 GQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQ 332
G+V TK L E T+ ++A+ +P R T+ F++
Sbjct: 3392 GEVKVTKLLDRETISGYTLTVQASDNGSPPRVNTTTVNIDVSDVNDNAPV-----FSRGN 3446
Query: 333 YSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLD 392
YS + E G +L L +++ P F + + F +N G ++ ++
Sbjct: 3447 YSVIIQENKPVGFSVLQLVVTDEDSSHNGPPFFFTIVTGNDEKAFEVNPQGVLLTSSAIK 3506
Query: 393 YETTSNYFYQVMVTDSISNDTASIN-ISVEDVNE 425
+ +Y QV V D+ +S+ I + + E
Sbjct: 3507 RKEKDHYLLQVKVADNGKPQLSSLTYIDIRVIEE 3540
Score = 91.9 bits (218), Expect = 9e-18
Identities = 101/437 (23%), Positives = 168/437 (38%), Gaps = 24/437 (5%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
V + V D+NDN P + YAV +SE +D D P+ + Y +
Sbjct: 2272 VDIIVDDINDNPPVFAQQSYAVTLSEASVIGTSVVQVRATDSDSE-PNRGISYQMFGNHS 2330
Query: 154 SEYLGFENELEP-IIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQN 212
+ F + +I + + LD+E TI +R D G P L SD + V V D +
Sbjct: 2331 KSHDHFHVDSSTGLISLLRTLDYEQSRQHTIFVRAVDGGMPTLSSDVIVTVDVTDLNGNP 2390
Query: 213 PKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYS--STGDHKQLIVVNK 270
P F + Y A + + A G F+T + A D D LQYS S DHK V++
Sbjct: 2391 PLFEQQIYEARISEHAPHGHFVTC----VKAYDADSSDIDKLQYSILSGNDHKH-FVIDS 2445
Query: 271 DTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQ 330
TG + + L P ++ L + D R F Q
Sbjct: 2446 ATGIITLSNLHRHALKPFYSLNLSVS--DGVFR------SSTQVHVTVIGGNLHSPAFLQ 2497
Query: 331 KQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRS 390
+Y ++E A ++++ + T ++ V+D + D+F IN G++
Sbjct: 2498 NEYEVELAENAPLHTLVMEVKTTDGDSGIYGHVTYHIVNDFA-KDRFYINERGQIFTLEK 2556
Query: 391 LDYETTSNYFYQV--MVTDSISNDT-ASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXX 447
LD ET + V M D+ ++N+ + D N+ P+FR +YE
Sbjct: 2557 LDRETPAEKVISVRLMAKDAGGKVAFCTVNVILTDDNDNAPQFRATKYEVNIGSSAAKGT 2616
Query: 448 XXXXXXXXXXXVAHDGDAGTLALSLAGQHAR-MFYINASGDLFLREEAIGNLNSSSLHLV 506
+ D T A+ + + IN + +E++ L +
Sbjct: 2617 SVVKSASDADE-GSNADI-TYAIEADSESVKENLEINKLSGVITTKESLIGLENEFFTFF 2674
Query: 507 ATAIDSGIPPRQTSVPV 523
A+D+G P +++ V V
Sbjct: 2675 VRAVDNGSPSKESVVLV 2691
Score = 91.9 bits (218), Expect = 9e-18
Identities = 131/530 (24%), Positives = 201/530 (37%), Gaps = 43/530 (8%)
Query: 8 SFFISEDTPIGSIIGTLSV--NGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDR 65
+F +SED P+G+ I + +G L + + I S L L ++LD
Sbjct: 2711 TFTVSEDVPVGTEIDLIRAEHSGTVLYSLVKGNTPESNRDESFVIDRQSGRLKLEKSLDH 2770
Query: 66 EEKIGPSNVYVNVRCDRRRTTDPSFV--IPVSVRVWDVNDNAPQWEGAPYAVRVSETXXX 123
E + RC + D V + VS++V D NDN+P +E +PY + E
Sbjct: 2771 ETTKW-YQFSILARCTQ---DDHEMVASVDVSIQVKDANDNSPVFESSPYEAFIVENLPG 2826
Query: 124 XXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYL-GFENELEP-IIVVKKPLDFETVNNF 181
SD D G + + Y++ E + F +E I K LD E +N+
Sbjct: 2827 GSRVIQIRASDADS-GTNGQVMYSLDQSQSVEVIESFAINMETGWITTLKELDHEKRDNY 2885
Query: 182 TIKLRVQDQGSPPLYSDTTL-QVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGP 240
IK+ D G S T + VTV D +D P+FT E Y + +D +G +
Sbjct: 2886 QIKVVASDHGEKIQLSSTAIVDVTVTDVNDSPPRFTAEIYKGTVSEDDPQGGVIAI---- 2941
Query: 241 ISAADQDL-GINAPLQYSSTGDHK--QLIVVN-KDTGQVAATKQLIAELDPSVTIVLKAT 296
+S D D IN + Y TG Q V ++ +V K L E + + + AT
Sbjct: 2942 LSTTDADSEEINRQVTYFITGGDPLGQFAVETIQNEWKVYVKKPLDREKRDNYLLTITAT 3001
Query: 297 QVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQ-YSTTVSEGASPGSVLLTLTTVPQ 355
T +K YS T+ E PG +++ ++
Sbjct: 3002 D---------GTFSSKAIVEVKVLDANDNSPVCEKTLYSDTIPEDVLPGKLIMQISAT-- 3050
Query: 356 NTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTDSISN-DT 413
+ + R + Y S +KF +N + GE+ LD E + Y V TD
Sbjct: 3051 DADIRSNAEITYTLLGSGAEKFKLNPDTGELKTSTPLDREEQAVYHLLVRATDGGGRFCQ 3110
Query: 414 ASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGDAG---TLAL 470
ASI +++EDVN+ P F Y A D DAG +
Sbjct: 3111 ASIVVTLEDVNDNAPEFSADPY------AITVFENTEPGTLLTRVQATDADAGLNRKILY 3164
Query: 471 SLAGQHARMFYINASGDLFLREEAIGNLNSSSLHLVATAIDSGIPPRQTS 520
SL F IN + E+ + + L A+D G+P R T+
Sbjct: 3165 SLIDSADGQFSINELSGIIQLEKPLDRELQAVYTLSLKAVDQGLPRRLTA 3214
Score = 81.8 bits (193), Expect = 1e-14
Identities = 99/441 (22%), Positives = 176/441 (39%), Gaps = 33/441 (7%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKN-LTLLRALDREEKI 69
++E+ P+ +++ + S G +T + A + + L LDRE
Sbjct: 2504 LAENAPLHTLVMEVKTTDGDSGIYGHVTYHIVNDFAKDRFYINERGQIFTLEKLDRET-- 2561
Query: 70 GPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXX 129
P+ ++VR + V+V + D NDNAPQ+ Y V + +
Sbjct: 2562 -PAEKVISVRLMAKDAGGKVAFCTVNVILTDDNDNAPQFRATKYEVNIGSSAAKGTSVVK 2620
Query: 130 XXXSDRDQPGPHSALHYAVLPGPHSEYLGFE-NELEPIIVVKKPLDFETVNNFTIKLRVQ 188
SD D+ G ++ + YA+ S E N+L +I K+ L FT +R
Sbjct: 2621 SA-SDADE-GSNADITYAIEADSESVKENLEINKLSGVITTKESLIGLENEFFTFFVRAV 2678
Query: 189 DQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDL 248
D GSP S + V +L + Q PKF+ YT + +D GT + + A+
Sbjct: 2679 DNGSPSKESVVLVYVKILPPEMQLPKFSEPFYTFTVSEDVPVGTEI-----DLIRAEHSG 2733
Query: 249 GINAPLQYSST--GDHKQLIVVNKDTGQVAATKQLIAELDP--SVTIVLKATQVDNPDRY 304
+ L +T + + V+++ +G++ K L E +I+ + TQ D+
Sbjct: 2734 TVLYSLVKGNTPESNRDESFVIDRQSGRLKLEKSLDHETTKWYQFSILARCTQDDH---- 2789
Query: 305 ALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPL 364
+ F Y + E GS ++ + + + +
Sbjct: 2790 --EMVASVDVSIQVKDANDNSPVFESSPYEAFIVENLPGGSRVIQIRA--SDADSGTNGQ 2845
Query: 365 QFYVSDRS----FLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTDSIS----NDTAS 415
Y D+S ++ FAIN G + + LD+E NY +V+ +D + TA
Sbjct: 2846 VMYSLDQSQSVEVIESFAINMETGWITTLKELDHEKRDNYQIKVVASDHGEKIQLSSTAI 2905
Query: 416 INISVEDVNEWEPRFRHPQYE 436
++++V DVN+ PRF Y+
Sbjct: 2906 VDVTVTDVNDSPPRFTAEIYK 2926
Score = 79.0 bits (186), Expect = 7e-14
Identities = 78/364 (21%), Positives = 141/364 (38%), Gaps = 19/364 (5%)
Query: 169 VKKPLDFETVNNFTIKLRVQ-DQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDD 227
++K LD ET + + + Q + + + + V DA+D +P F Y A + ++
Sbjct: 2764 LEKSLDHETTKWYQFSILARCTQDDHEMVASVDVSIQVKDANDNSPVFESSPYEAFIVEN 2823
Query: 228 AEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIV----VNKDTGQVAATKQLIA 283
G+ + I A+D D G N + YS ++ +N +TG + K+L
Sbjct: 2824 LPGGSRVIQ----IRASDADSGTNGQVMYSLDQSQSVEVIESFAINMETGWITTLKELDH 2879
Query: 284 ELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASP 343
E + I + A+ D+ ++ L++ +FT + Y TVSE
Sbjct: 2880 EKRDNYQIKVVAS--DHGEKIQLSSTAIVDVTVTDVNDSPP--RFTAEIYKGTVSEDDPQ 2935
Query: 344 GSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFA---INNAGEVILRRSLDYETTSNYF 400
G V+ L+T ++E + ++++ L +FA I N +V +++ LD E NY
Sbjct: 2936 GGVIAILSTTDADSEEINRQVTYFITGGDPLGQFAVETIQNEWKVYVKKPLDREKRDNYL 2995
Query: 401 YQVMVTDSISNDTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXVA 460
+ TD + A + + V D N+ P Y +
Sbjct: 2996 LTITATDGTFSSKAIVEVKVLDANDNSPVCEKTLYSDTIPEDVLPGKLIMQISATDADIR 3055
Query: 461 HDGDAGTLALSLAGQHARMFYINASGDLFLREEAIGNLNSSSLHLVATAIDSGIPPRQTS 520
+ + + +L G A F +N + + HL+ A D G Q S
Sbjct: 3056 SNAE---ITYTLLGSGAEKFKLNPDTGELKTSTPLDREEQAVYHLLVRATDGGGRFCQAS 3112
Query: 521 VPVT 524
+ VT
Sbjct: 3113 IVVT 3116
Score = 74.9 bits (176), Expect = 1e-12
Identities = 96/432 (22%), Positives = 161/432 (37%), Gaps = 24/432 (5%)
Query: 101 VNDNAPQWEGA-PYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGF 159
VN + PQ+ P ++V E +D D G + L YAV G
Sbjct: 709 VNAHIPQFRSTLPTGIQVKENQPVGSSVIFMNSTDLDT-GFNGKLVYAVSGGNEDSCFMI 767
Query: 160 ENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEH 219
+ E ++ + PLD ET + +T+ + V D G P + L V V+DA+D P+F E
Sbjct: 768 DMETG-MLKILSPLDRETTDKYTLNITVYDLGIPQKAAWRLLHVVVVDANDNPPEFLQES 826
Query: 220 YTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATK 279
Y + +D E + + + A D+DLG N + YS D ++ TG V +
Sbjct: 827 YFVEVSEDKEVHSEII----QVEATDKDLGPNGHVTYSILTD-TDTFSIDSVTGVVNIAR 881
Query: 280 QLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSE 339
L EL ++ ++A + +T+ F Y V E
Sbjct: 882 PLDRELQHEHSLKIEARDQAREEPQLFSTVVVKVSLEDVNDNPPT---FIPPNYRVKVRE 938
Query: 340 GASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNY 399
G+V++ L + + +++ + D + +G V + + LD+E Y
Sbjct: 939 DLPEGTVIMWLEAHDPDLG-QSGQVRYSLLDHGEGNFDVDKLSGAVRIVQQLDFEKKQVY 997
Query: 400 FYQVMVTDS---IS-NDTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXX 455
V D +S + T + + V DVNE HP
Sbjct: 998 NLTVRAKDKGKPVSLSSTCYVEVEVVDVNE----NLHPPVFSSFVEKGTVKEDAPVGSLV 1053
Query: 456 XXXVAHDGDA---GTLALSLA-GQHARMFYINASGDLFLREEAIGNLNSSSLHLVATAID 511
AHD DA G + S+ G +F I + + + ++S L A D
Sbjct: 1054 MTVSAHDEDAGRDGEIRYSIRDGSGVGVFKIGEETGVIETSDRLDRESTSHYWLTVFATD 1113
Query: 512 SGIPPRQTSVPV 523
G+ P + + +
Sbjct: 1114 QGVVPLSSFIEI 1125
Score = 70.5 bits (165), Expect = 2e-11
Identities = 98/441 (22%), Positives = 175/441 (39%), Gaps = 25/441 (5%)
Query: 7 ESFFI--SEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALD 64
ES+F+ SED + S I + G +T + I + + + R LD
Sbjct: 825 ESYFVEVSEDKEVHSEIIQVEATDKDLGPNGHVTYSILTDTDTFSIDSVTGVVNIARPLD 884
Query: 65 REEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXX 124
RE + S + + R R + V V + DVNDN P + Y V+V E
Sbjct: 885 RELQHEHS-LKIEARDQAREEPQLFSTVVVKVSLEDVNDNPPTFIPPNYRVKVREDLPEG 943
Query: 125 XXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIK 184
D D G + Y++L H E ++L + + + LDFE + +
Sbjct: 944 TVIMWLEAHDPDL-GQSGQVRYSLL--DHGEGNFDVDKLSGAVRIVQQLDFEKKQVYNLT 1000
Query: 185 LRVQDQGSPPLYSDTT-LQVTVLDADD--QNPKFTYEHYTALLPDDAEEGTFLTTSPGPI 241
+R +D+G P S T ++V V+D ++ P F+ + +DA G+ + T +
Sbjct: 1001 VRAKDKGKPVSLSSTCYVEVEVVDVNENLHPPVFSSFVEKGTVKEDAPVGSLVMT----V 1056
Query: 242 SAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDN 300
SA D+D G + ++YS G + + ++TG + + +L E + + AT
Sbjct: 1057 SAHDEDAGRDGEIRYSIRDGSGVGVFKIGEETGVIETSDRLDRESTSHYWLTVFAT---- 1112
Query: 301 PDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFR 360
D+ + Q ++ Y + E SP V +
Sbjct: 1113 -DQGVVPLSSFIEIYIEVEDVNDNAPQTSEPVYYPEIMEN-SPKDVSVVQIEAFDPDSSS 1170
Query: 361 ESPLQFYVSDRSFLDKFAINNAGEVI--LRRSLDYETTSNYFYQVMVTDSIS---NDTAS 415
L + ++ + F+I+ +I R LD E + +V VTD+ S + A
Sbjct: 1171 NDKLMYKITSGNPQGFFSIHPKTGLITTTSRKLDREQQDEHILEVTVTDNGSPPKSTIAR 1230
Query: 416 INISVEDVNEWEPRFRHPQYE 436
+ + + D N+ +P+F Y+
Sbjct: 1231 VIVKILDENDNKPQFLQKFYK 1251
Score = 68.1 bits (159), Expect = 1e-10
Identities = 81/351 (23%), Positives = 150/351 (42%), Gaps = 22/351 (6%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
V V V N ++P + Y V ++E +D D G + + Y ++
Sbjct: 2481 VHVTVIGGNLHSPAFLQNEYEVELAENAPLHTLVMEVKTTDGDS-GIYGHVTYHIV-NDF 2538
Query: 154 SEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNP 213
++ + NE I ++K LD ET I +R+ + + + T+ V + D +D P
Sbjct: 2539 AKDRFYINERGQIFTLEK-LDRETPAEKVISVRLMAKDAGGKVAFCTVNVILTDDNDNAP 2597
Query: 214 KFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDH---KQLIVVNK 270
+F Y + A +GT + SA+D D G NA + Y+ D K+ + +NK
Sbjct: 2598 QFRATKYEVNIGSSAAKGTSVVK-----SASDADEGSNADITYAIEADSESVKENLEINK 2652
Query: 271 DTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQ 330
+G + + LI + T ++A +P + ++ + +F++
Sbjct: 2653 LSGVITTKESLIGLENEFFTFFVRAVDNGSPSKESVVLVYVKILPPEMQLP-----KFSE 2707
Query: 331 KQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRR 389
Y+ TVSE G+ + L + S ++ + + + F I+ +G + L +
Sbjct: 2708 PFYTFTVSEDVPVGTE-IDLIRAEHSGTVLYSLVKGNTPESNRDESFVIDRQSGRLKLEK 2766
Query: 390 SLDYETTSNYFYQVMV--TDSISNDTASINIS--VEDVNEWEPRFRHPQYE 436
SLD+ETT Y + ++ T AS+++S V+D N+ P F YE
Sbjct: 2767 SLDHETTKWYQFSILARCTQDDHEMVASVDVSIQVKDANDNSPVFESSPYE 2817
Score = 64.9 bits (151), Expect = 1e-09
Identities = 121/533 (22%), Positives = 201/533 (37%), Gaps = 54/533 (10%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEKIG 70
+SE IGS +G ++ + S ++ G A I P S + +ALD E
Sbjct: 1679 LSETVSIGSFVGMVTAHSQSSVVY---EIKDGNTGDAFDINPHSGTIITQKALDFETL-- 1733
Query: 71 PSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXX 130
+Y + S V V + D NDNAP + A Y +SE+
Sbjct: 1734 --PIYTLI-IQGTNMAGLSTNTTVLVHLQDENDNAPVFMQAEYTGLISESASINSVVLTD 1790
Query: 131 X-------XSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTI 183
+D D+ +++ V P H+ Y ++ I V LD+E + F
Sbjct: 1791 RNVPLVIRAADADKDSNALLVYHIVEPSVHT-YFAIDSSTGAIHTVLS-LDYEETSIFHF 1848
Query: 184 KLRVQDQGSPPLYSDTTLQVT--VLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPI 241
++V D G+P L+++ VT V+D +D P F Y A L +G + T +
Sbjct: 1849 TVQVHDMGTPRLFAEYAANVTVHVIDINDCPPVFAKPLYEASLLLPTYKGVKVIT----V 1904
Query: 242 SAADQDLGINAPLQYSST-GDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDN 300
+A D D + L YS T G+ + ++ TG A T Q +L + ++A+
Sbjct: 1905 NATDADSSAFSQLIYSITEGNIGEKFSMDYKTG--ALTVQNTTQLRSRYELTVRASD--- 1959
Query: 301 PDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFR 360
R+A T L+FTQ YS V E ++ L +T + +
Sbjct: 1960 -GRFAGLT----SVKINVKESKESHLKFTQDVYSAVVKENSTEAETLAVITAI--GSPIN 2012
Query: 361 ESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSISNDTAS----- 415
E PL +++ + +F I+ V+ ++ + V+V + I S
Sbjct: 2013 E-PLFYHILNPD--RRFKISRTSGVLSTTGTPFDREQQEAFDVVV-EVIEEHKPSAVAHV 2068
Query: 416 -INISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGDAGTLALSLAG 474
+ + VED N+ P F + Y V D
Sbjct: 2069 VVKVIVEDQNDNAPVFVNLPY----YAVVKVDTEVGHVIRYVTAVDRDSGRNGEVHYYLK 2124
Query: 475 QHARMFYINASGDLFLREE-AIGNLNSSSLHLVATAIDSGIP--PRQTSVPVT 524
+H F I G++ L+++ + LN L + A D G P + VP+T
Sbjct: 2125 EHHEHFQIGPLGEISLKKQFELDTLNKEYL-VTVVAKDGGNPAFSAEVIVPIT 2176
Score = 64.9 bits (151), Expect = 1e-09
Identities = 84/355 (23%), Positives = 149/355 (41%), Gaps = 33/355 (9%)
Query: 92 IPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPG 151
+ V V V D NDNAP + PY V DRD G + +HY +
Sbjct: 2068 VVVKVIVEDQNDNAPVFVNLPYYAVVKVDTEVGHVIRYVTAVDRDS-GRNGEVHYYL--K 2124
Query: 152 PHSEYLGFENELEPI--IVVKKPLDFETVN-NFTIKLRVQDQGSPPLYSDTTLQVTVLDA 208
H E+ ++ P+ I +KK + +T+N + + + +D G+P ++ + +TV+
Sbjct: 2125 EHHEHF----QIGPLGEISLKKQFELDTLNKEYLVTVVAKDGGNPAFSAEVIVPITVM-- 2178
Query: 209 DDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSST-GDHKQLIV 267
+ P F Y+A + + + SP A+ G+ + YS T GD
Sbjct: 2179 NKAMPVFEKPFYSAEIAESIQ-----VHSPVVHVQANSPEGLK--VFYSITDGDPFSQFT 2231
Query: 268 VNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQ 327
+N +TG + L E P+ + ++AT D A +
Sbjct: 2232 INFNTGVINVIAPLDFEAHPAYKLSIRAT-----DSLTGAHAEVFVDIIVDDINDNPPV- 2285
Query: 328 FTQKQYSTTVSEGASPGSVLLTLTTVPQNTE-FRESPLQFYVSDRSFLDKFAINNA-GEV 385
F Q+ Y+ T+SE + G+ ++ + ++E R Q + + D F ++++ G +
Sbjct: 2286 FAQQSYAVTLSEASVIGTSVVQVRATDSDSEPNRGISYQMFGNHSKSHDHFHVDSSTGLI 2345
Query: 386 ILRRSLDYETTSNYFYQVMVTD----SISNDTASINISVEDVNEWEPRFRHPQYE 436
L R+LDYE + + V D ++S+D + + V D+N P F YE
Sbjct: 2346 SLLRTLDYEQSRQHTIFVRAVDGGMPTLSSDVI-VTVDVTDLNGNPPLFEQQIYE 2399
Score = 60.5 bits (140), Expect = 3e-08
Identities = 67/280 (23%), Positives = 110/280 (39%), Gaps = 20/280 (7%)
Query: 167 IVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPD 226
I+V KPLD E +N+ + + D + L T + + V+D +D P+F+ Y ++P+
Sbjct: 1411 IIVAKPLDAEQKSNYNLTVEATDGTTTIL---TQVFIKVIDTNDHRPQFSTSKYEVVIPE 1467
Query: 227 DAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKD--TGQVAATKQLIAE 284
D T + ISA DQD S+ D L D TG + +++L E
Sbjct: 1468 DTAPETEIL----QISAVDQDEKNKLIYTLQSSRDPLSLKKFRLDPATGSLYTSEKLDHE 1523
Query: 285 LDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPG 344
+ + D P + A + FT Y V E A+ G
Sbjct: 1524 AVSPAHLTVMVRDQDVPVKRNFARIVVNVSDTNDHAP-----WFTASSYKGRVYESAAVG 1578
Query: 345 SVLLTLTTVPQNTEFRESPLQFYVSDR--SFLDKFAINNA-GEVILRRSLDYETTSNYFY 401
SV+L +T + ++ L S + + F I+ G + + LD + Y
Sbjct: 1579 SVVLQVTALDKDKGKNAEVLYSIESGNIGNIGNSFMIDPVLGSIKTAKELDRSNQAEYDL 1638
Query: 402 QVMVTDSIS---NDTASINISVEDVNEWEPRFRHPQYEFE 438
V TD S ++ S+ I V + P+F +Y E
Sbjct: 1639 MVKATDKGSPPMSEITSVRIFVTIADNASPKFTSKEYSVE 1678
Score = 60.1 bits (139), Expect = 3e-08
Identities = 85/414 (20%), Positives = 156/414 (37%), Gaps = 28/414 (6%)
Query: 87 DPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHY 146
+P+F V V + +N P +E Y+ ++E+ + + + Y
Sbjct: 2164 NPAFSAEVIVPITVMNKAMPVFEKPFYSAEIAESIQVHSPVVHVQANSPEG----LKVFY 2219
Query: 147 AVLPG-PHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTV 205
++ G P S++ N +I V PLDFE + + +R D + +++ + + V
Sbjct: 2220 SITDGDPFSQFT--INFNTGVINVIAPLDFEAHPAYKLSIRATDSLTGA-HAEVFVDIIV 2276
Query: 206 LDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQL 265
D +D P F + Y L E + + TS + A D D N + Y G+H +
Sbjct: 2277 DDINDNPPVFAQQSYAVTL----SEASVIGTSVVQVRATDSDSEPNRGISYQMFGNHSKS 2332
Query: 266 ---IVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXX 322
V+ TG ++ + L E TI ++A VD + TL
Sbjct: 2333 HDHFHVDSSTGLISLLRTLDYEQSRQHTIFVRA--VDG----GMPTLSSDVIVTVDVTDL 2386
Query: 323 XXXLQ-FTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAINN 381
F Q+ Y +SE A G + + ++ + LQ+ + + F I++
Sbjct: 2387 NGNPPLFEQQIYEARISEHAPHGHFVTCVKAYDADSSDIDK-LQYSILSGNDHKHFVIDS 2445
Query: 382 AGEVILRRSLDYETTSNYF-YQVMVTDSISNDTASINISVEDVNEWEPRFRHPQYEFEXX 440
A +I +L ++ + V+D + + ++++V N P F +YE E
Sbjct: 2446 ATGIITLSNLHRHALKPFYSLNLSVSDGVFRSSTQVHVTVIGGNLHSPAFLQNEYEVELA 2505
Query: 441 XXXXXXXXXXXXXXXXXXVAHDGDAGTLALSLAGQHAR-MFYINASGDLFLREE 493
G G + + A+ FYIN G +F E+
Sbjct: 2506 ENAPLHTLVMEVKTTD---GDSGIYGHVTYHIVNDFAKDRFYINERGQIFTLEK 2556
Score = 46.8 bits (106), Expect = 3e-04
Identities = 30/109 (27%), Positives = 56/109 (51%), Gaps = 6/109 (5%)
Query: 173 LDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGT 232
L+ E +++T+ ++ ++ + + + T ++V VLD +D P F+ Y+ LP E T
Sbjct: 108 LNREVKDHYTLIVKALEKNTN-VEARTKVRVQVLDTNDLRPLFSPTSYSVSLP----ENT 162
Query: 233 FLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQL 281
+ TS +SA D D+G N YS D + ++ +G + T +L
Sbjct: 163 AIRTSIARVSATDADIGTNGEFYYSFK-DRTDMFAIHPTSGVIVLTGRL 210
>D87469-1|BAA13407.2| 2854|Homo sapiens KIAA0279 protein protein.
Length = 2854
Score = 126 bits (303), Expect = 5e-28
Identities = 100/361 (27%), Positives = 163/361 (45%), Gaps = 20/361 (5%)
Query: 81 DRRRTTDP-SFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPG 139
D+ R P S V + V D NDNAPQ+ Y V+V E SDRD+ G
Sbjct: 302 DQGRDPGPRSTTAAVFLSVEDDNDNAPQFSEKRYVVQVREDVTPGAPVLRVTASDRDK-G 360
Query: 140 PHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDT 199
++ +HY+++ G + + + VV PLD+ET +T+++R QD G PPL + +
Sbjct: 361 SNAVVHYSIMSGNARGQFYLDAQTGALDVV-SPLDYETTKEYTLRVRAQDGGRPPLSNVS 419
Query: 200 TL-QVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSS 258
L V VLD +D P F + A + + G + + A D D G NA L+Y
Sbjct: 420 GLVTVQVLDINDNAPIFVSTPFQATVLESVPLGYLVL----HVQAIDADAGDNARLEYRL 475
Query: 259 TG-DHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXX 317
G H +N TG ++ +L E + ++A P A A++
Sbjct: 476 AGVGHDFPFTINNGTGWISVAAELDREEVDFYSFGVEARDHGTPALTASASVSVTVLDVN 535
Query: 318 XXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKF 377
FTQ +Y+ ++E A+ G+ ++T++ V ++ S + + ++ + ++F
Sbjct: 536 DNNPT-----FTQPEYTVRLNEDAAVGTSVVTVSAVDRDA---HSVITYQITSGNTRNRF 587
Query: 378 AI---NNAGEVILRRSLDYETTSNYFYQVMVTDSISNDTASINISVEDVNEWEPRFRHPQ 434
+I + G V L LDY+ Y V +D DTA I ++V D N P F+
Sbjct: 588 SITSQSGGGLVSLALPLDYKLERQYVLAVTASDGTRQDTAQIVVNVTDANTHRPVFQSSH 647
Query: 435 Y 435
Y
Sbjct: 648 Y 648
Score = 103 bits (247), Expect = 3e-21
Identities = 100/436 (22%), Positives = 174/436 (39%), Gaps = 23/436 (5%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
V+V+V D+NDNAP + P+ V E+ D D G ++ L Y L G
Sbjct: 422 VTVQVLDINDNAPIFVSTPFQATVLESVPLGYLVLHVQAIDADA-GDNARLEYR-LAGVG 479
Query: 154 SEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNP 213
++ N I V LD E V+ ++ + +D G+P L + ++ VTVLD +D NP
Sbjct: 480 HDFPFTINNGTGWISVAAELDREEVDFYSFGVEARDHGTPALTASASVSVTVLDVNDNNP 539
Query: 214 KFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKD-T 272
FT YT L +DA GT + T +SA D+D Q +S + + ++
Sbjct: 540 TFTQPEYTVRLNEDAAVGTSVVT----VSAVDRDAHSVITYQITSGNTRNRFSITSQSGG 595
Query: 273 GQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQ 332
G V+ L +L+ + + A+ D + F
Sbjct: 596 GLVSLALPLDYKLERQYVLAVTASDGTRQDTAQIVV--------NVTDANTHRPVFQSSH 647
Query: 333 YSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSL 391
Y+ V+E G+ ++ ++ ++T + + +++ D + +F I+ + G V + L
Sbjct: 648 YTVNVNEDRPAGTTVVLISATDEDTG-ENARITYFMEDS--IPQFRIDADTGAVTTQAEL 704
Query: 392 DYETTSNYFYQVMVTDS---ISNDTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXX 448
DYE +Y + D+ +DT + I V DVN+ P+F Y+
Sbjct: 705 DYEDQVSYTLAITARDNGIPQKSDTTYLEILVNDVNDNAPQFLRDSYQGSVYEDVPPFTS 764
Query: 449 XXXXXXXXXXVAHDGDAGTLALSLAGQHARMFYINASGDLFLREEAIGNLNSSSLHLVAT 508
+G F + ++ + + N + L A
Sbjct: 765 VLQISATDRDSGLNGRV-FYTFQGGDDGDGDFIVESTSGIVRTLRRLDRENVAQYVLRAY 823
Query: 509 AIDSGIPPRQTSVPVT 524
A+D G+PP +T + VT
Sbjct: 824 AVDKGMPPARTPMEVT 839
Score = 85.0 bits (201), Expect = 1e-15
Identities = 93/393 (23%), Positives = 160/393 (40%), Gaps = 22/393 (5%)
Query: 52 PGSKNLTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGA 111
P + +T LDRE K S V S + +++ V D ND+ P +E
Sbjct: 167 PVTGAVTTAEELDRETK---STHVFRVTAQDHGMPRRSALATLTILVTDTNDHDPVFEQQ 223
Query: 112 PYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGP-HSEYLGFE-NELEPIIVV 169
Y + E +D D P P++ + Y +L G S FE + +I
Sbjct: 224 EYKESLRENLEVGYEVLTVRATDGDAP-PNANILYRLLEGSGGSPSEVFEIDPRSGVIRT 282
Query: 170 KKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQV--TVLDADDQNPKFTYEHYTALLPDD 227
+ P+D E V ++ + + DQG P TT V +V D +D P+F+ + Y + +D
Sbjct: 283 RGPVDREEVESYQLTVEASDQGRDPGPRSTTAAVFLSVEDDNDNAPQFSEKRYVVQVRED 342
Query: 228 AEEGTFLTTSPGPISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELD 286
G + ++A+D+D G NA + YS +G+ + ++ TG + L E
Sbjct: 343 VTPGAPVLR----VTASDRDKGSNAVVHYSIMSGNARGQFYLDAQTGALDVVSPLDYETT 398
Query: 287 PSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSV 346
T+ ++A P ++ L F + TV E G +
Sbjct: 399 KEYTLRVRAQDGGRPPLSNVSGLVTVQVLDINDNAPI----FVSTPFQATVLESVPLGYL 454
Query: 347 LLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAINN-AGEVILRRSLDYETTSNYFYQVMV 405
+L + + + + L++ ++ F INN G + + LD E Y + V
Sbjct: 455 VLHVQAIDADAG-DNARLEYRLAGVGHDFPFTINNGTGWISVAAELDREEVDFYSFGVEA 513
Query: 406 TD---SISNDTASINISVEDVNEWEPRFRHPQY 435
D +AS++++V DVN+ P F P+Y
Sbjct: 514 RDHGTPALTASASVSVTVLDVNDNNPTFTQPEY 546
Score = 84.2 bits (199), Expect = 2e-15
Identities = 91/417 (21%), Positives = 166/417 (39%), Gaps = 17/417 (4%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEKIG 70
++ED P G+ + +S + + + IT +++ I + +T LD E+++
Sbjct: 652 VNEDRPAGTTVVLISATDEDTGENARITYFMEDSIPQFRIDADTGAVTTQAELDYEDQVS 711
Query: 71 PSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXX 130
+ + +D +++ + V DVNDNAPQ+ Y V E
Sbjct: 712 YTLAITARDNGIPQKSDTTYL---EILVNDVNDNAPQFLRDSYQGSVYEDVPPFTSVLQI 768
Query: 131 XXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQ 190
+DRD G + + Y G + I+ + LD E V + ++ D+
Sbjct: 769 SATDRDS-GLNGRVFYTFQGGDDGDGDFIVESTSGIVRTLRRLDRENVAQYVLRAYAVDK 827
Query: 191 GSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGI 250
G PP + + VTVLD +D P F + + + EE + + + ++A D D G
Sbjct: 828 GMPPARTPMEVTVTVLDVNDNPPVFEQDEFDVFV----EENSPIGLAVARVTATDPDEGT 883
Query: 251 NAPLQYSST-GDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATL 309
NA + Y G+ ++ ++ +G++ A L E P +V++AT R AT+
Sbjct: 884 NAQIMYQIVEGNIPEVFQLDIFSGELTALVDLDYEDRPEYVLVIQATSAPLVSR---ATV 940
Query: 310 XXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVS 369
+ Y T S + PG + VP + L +
Sbjct: 941 HVRLLDRNDNPPVLGNFEILFNNYVTNRS-SSFPGG---AIGRVPAHDPDISDSLTYSFE 996
Query: 370 DRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTDSISNDTASINISVEDVNE 425
+ L +N + GE+ L R+LD V+V+D + + TA + V + +
Sbjct: 997 RGNELSLVLLNASTGELKLSRALDNNRPLEAIMSVLVSDGVHSVTAQCALRVTIITD 1053
Score = 71.7 bits (168), Expect = 1e-11
Identities = 74/340 (21%), Positives = 138/340 (40%), Gaps = 22/340 (6%)
Query: 103 DNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHY---AVLPGPHSEYLGF 159
+ APQ++ Y V E D D+ G L Y A+ +++
Sbjct: 107 NTAPQFQPPSYQATVPENQPAGTPVASLRAIDPDE-GEAGRLEYTMDALFDSRSNQFFSL 165
Query: 160 ENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEH 219
+ + + + LD ET + ++ QD G P + TL + V D +D +P F +
Sbjct: 166 D-PVTGAVTTAEELDRETKSTHVFRVTAQDHGMPRRSALATLTILVTDTNDHDPVFEQQE 224
Query: 220 YTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQY----SSTGDHKQLIVVNKDTGQV 275
Y L ++ E G + T + A D D NA + Y S G ++ ++ +G +
Sbjct: 225 YKESLRENLEVGYEVLT----VRATDGDAPPNANILYRLLEGSGGSPSEVFEIDPRSGVI 280
Query: 276 AATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYST 335
+ E S + ++A+ D +T QF++K+Y
Sbjct: 281 RTRGPVDREEVESYQLTVEASD-QGRDPGPRST--TAAVFLSVEDDNDNAPQFSEKRYVV 337
Query: 336 TVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYE 394
V E +PG+ +L +T ++ + + + + + + +F ++ G + + LDYE
Sbjct: 338 QVREDVTPGAPVLRVTASDRD-KGSNAVVHYSIMSGNARGQFYLDAQTGALDVVSPLDYE 396
Query: 395 TTSNYFYQVMVTDS----ISNDTASINISVEDVNEWEPRF 430
TT Y +V D +SN + + + V D+N+ P F
Sbjct: 397 TTKEYTLRVRAQDGGRPPLSNVSGLVTVQVLDINDNAPIF 436
Score = 69.3 bits (162), Expect = 6e-11
Identities = 73/339 (21%), Positives = 136/339 (40%), Gaps = 19/339 (5%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
+ V V D N + P ++ + Y V V+E +D D G ++ + Y +
Sbjct: 629 IVVNVTDANTHRPVFQSSHYTVNVNEDRPAGTTVVLISATDEDT-GENARITYFM----E 683
Query: 154 SEYLGFENELEP-IIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQN 212
F + + + + LD+E ++T+ + +D G P T L++ V D +D
Sbjct: 684 DSIPQFRIDADTGAVTTQAELDYEDQVSYTLAITARDNGIPQKSDTTYLEILVNDVNDNA 743
Query: 213 PKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTG--DHKQLIVVNK 270
P+F + Y + +D TS ISA D+D G+N + Y+ G D +V
Sbjct: 744 PQFLRDSYQGSVYEDVPP----FTSVLQISATDRDSGLNGRVFYTFQGGDDGDGDFIVES 799
Query: 271 DTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQ 330
+G V ++L + + VL+A VD A + F Q
Sbjct: 800 TSGIVRTLRRL--DRENVAQYVLRAYAVDKGMPPARTPMEVTVTVLDVNDNPPV---FEQ 854
Query: 331 KQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAINN-AGEVILRR 389
++ V E SP + + T E + + + + + + + F ++ +GE+
Sbjct: 855 DEFDVFVEEN-SPIGLAVARVTATDPDEGTNAQIMYQIVEGNIPEVFQLDIFSGELTALV 913
Query: 390 SLDYETTSNYFYQVMVTDSISNDTASINISVEDVNEWEP 428
LDYE Y + T + A++++ + D N+ P
Sbjct: 914 DLDYEDRPEYVLVIQATSAPLVSRATVHVRLLDRNDNPP 952
>AL390252-1|CAI13170.1| 2923|Homo sapiens cadherin, EGF LAG
seven-pass G-type receptor 2 (flamingo homolog,
Drosophila) protein.
Length = 2923
Score = 126 bits (303), Expect = 5e-28
Identities = 100/361 (27%), Positives = 163/361 (45%), Gaps = 20/361 (5%)
Query: 81 DRRRTTDP-SFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPG 139
D+ R P S V + V D NDNAPQ+ Y V+V E SDRD+ G
Sbjct: 371 DQGRDPGPRSTTAAVFLSVEDDNDNAPQFSEKRYVVQVREDVTPGAPVLRVTASDRDK-G 429
Query: 140 PHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDT 199
++ +HY+++ G + + + VV PLD+ET +T+++R QD G PPL + +
Sbjct: 430 SNAVVHYSIMSGNARGQFYLDAQTGALDVV-SPLDYETTKEYTLRVRAQDGGRPPLSNVS 488
Query: 200 TL-QVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSS 258
L V VLD +D P F + A + + G + + A D D G NA L+Y
Sbjct: 489 GLVTVQVLDINDNAPIFVSTPFQATVLESVPLGYLVL----HVQAIDADAGDNARLEYRL 544
Query: 259 TG-DHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXX 317
G H +N TG ++ +L E + ++A P A A++
Sbjct: 545 AGVGHDFPFTINNGTGWISVAAELDREEVDFYSFGVEARDHGTPALTASASVSVTVLDVN 604
Query: 318 XXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKF 377
FTQ +Y+ ++E A+ G+ ++T++ V ++ S + + ++ + ++F
Sbjct: 605 DNNPT-----FTQPEYTVRLNEDAAVGTSVVTVSAVDRDA---HSVITYQITSGNTRNRF 656
Query: 378 AI---NNAGEVILRRSLDYETTSNYFYQVMVTDSISNDTASINISVEDVNEWEPRFRHPQ 434
+I + G V L LDY+ Y V +D DTA I ++V D N P F+
Sbjct: 657 SITSQSGGGLVSLALPLDYKLERQYVLAVTASDGTRQDTAQIVVNVTDANTHRPVFQSSH 716
Query: 435 Y 435
Y
Sbjct: 717 Y 717
Score = 103 bits (247), Expect = 3e-21
Identities = 100/436 (22%), Positives = 174/436 (39%), Gaps = 23/436 (5%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
V+V+V D+NDNAP + P+ V E+ D D G ++ L Y L G
Sbjct: 491 VTVQVLDINDNAPIFVSTPFQATVLESVPLGYLVLHVQAIDADA-GDNARLEYR-LAGVG 548
Query: 154 SEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNP 213
++ N I V LD E V+ ++ + +D G+P L + ++ VTVLD +D NP
Sbjct: 549 HDFPFTINNGTGWISVAAELDREEVDFYSFGVEARDHGTPALTASASVSVTVLDVNDNNP 608
Query: 214 KFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKD-T 272
FT YT L +DA GT + T +SA D+D Q +S + + ++
Sbjct: 609 TFTQPEYTVRLNEDAAVGTSVVT----VSAVDRDAHSVITYQITSGNTRNRFSITSQSGG 664
Query: 273 GQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQ 332
G V+ L +L+ + + A+ D + F
Sbjct: 665 GLVSLALPLDYKLERQYVLAVTASDGTRQDTAQIVV--------NVTDANTHRPVFQSSH 716
Query: 333 YSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSL 391
Y+ V+E G+ ++ ++ ++T + + +++ D + +F I+ + G V + L
Sbjct: 717 YTVNVNEDRPAGTTVVLISATDEDTG-ENARITYFMEDS--IPQFRIDADTGAVTTQAEL 773
Query: 392 DYETTSNYFYQVMVTDS---ISNDTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXX 448
DYE +Y + D+ +DT + I V DVN+ P+F Y+
Sbjct: 774 DYEDQVSYTLAITARDNGIPQKSDTTYLEILVNDVNDNAPQFLRDSYQGSVYEDVPPFTS 833
Query: 449 XXXXXXXXXXVAHDGDAGTLALSLAGQHARMFYINASGDLFLREEAIGNLNSSSLHLVAT 508
+G F + ++ + + N + L A
Sbjct: 834 VLQISATDRDSGLNGRV-FYTFQGGDDGDGDFIVESTSGIVRTLRRLDRENVAQYVLRAY 892
Query: 509 AIDSGIPPRQTSVPVT 524
A+D G+PP +T + VT
Sbjct: 893 AVDKGMPPARTPMEVT 908
Score = 85.0 bits (201), Expect = 1e-15
Identities = 93/393 (23%), Positives = 160/393 (40%), Gaps = 22/393 (5%)
Query: 52 PGSKNLTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGA 111
P + +T LDRE K S V S + +++ V D ND+ P +E
Sbjct: 236 PVTGAVTTAEELDRETK---STHVFRVTAQDHGMPRRSALATLTILVTDTNDHDPVFEQQ 292
Query: 112 PYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGP-HSEYLGFE-NELEPIIVV 169
Y + E +D D P P++ + Y +L G S FE + +I
Sbjct: 293 EYKESLRENLEVGYEVLTVRATDGDAP-PNANILYRLLEGSGGSPSEVFEIDPRSGVIRT 351
Query: 170 KKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQV--TVLDADDQNPKFTYEHYTALLPDD 227
+ P+D E V ++ + + DQG P TT V +V D +D P+F+ + Y + +D
Sbjct: 352 RGPVDREEVESYQLTVEASDQGRDPGPRSTTAAVFLSVEDDNDNAPQFSEKRYVVQVRED 411
Query: 228 AEEGTFLTTSPGPISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELD 286
G + ++A+D+D G NA + YS +G+ + ++ TG + L E
Sbjct: 412 VTPGAPVLR----VTASDRDKGSNAVVHYSIMSGNARGQFYLDAQTGALDVVSPLDYETT 467
Query: 287 PSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSV 346
T+ ++A P ++ L F + TV E G +
Sbjct: 468 KEYTLRVRAQDGGRPPLSNVSGLVTVQVLDINDNAPI----FVSTPFQATVLESVPLGYL 523
Query: 347 LLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAINN-AGEVILRRSLDYETTSNYFYQVMV 405
+L + + + + L++ ++ F INN G + + LD E Y + V
Sbjct: 524 VLHVQAIDADAG-DNARLEYRLAGVGHDFPFTINNGTGWISVAAELDREEVDFYSFGVEA 582
Query: 406 TD---SISNDTASINISVEDVNEWEPRFRHPQY 435
D +AS++++V DVN+ P F P+Y
Sbjct: 583 RDHGTPALTASASVSVTVLDVNDNNPTFTQPEY 615
Score = 84.2 bits (199), Expect = 2e-15
Identities = 91/417 (21%), Positives = 166/417 (39%), Gaps = 17/417 (4%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEKIG 70
++ED P G+ + +S + + + IT +++ I + +T LD E+++
Sbjct: 721 VNEDRPAGTTVVLISATDEDTGENARITYFMEDSIPQFRIDADTGAVTTQAELDYEDQVS 780
Query: 71 PSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXX 130
+ + +D +++ + V DVNDNAPQ+ Y V E
Sbjct: 781 YTLAITARDNGIPQKSDTTYL---EILVNDVNDNAPQFLRDSYQGSVYEDVPPFTSVLQI 837
Query: 131 XXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQ 190
+DRD G + + Y G + I+ + LD E V + ++ D+
Sbjct: 838 SATDRDS-GLNGRVFYTFQGGDDGDGDFIVESTSGIVRTLRRLDRENVAQYVLRAYAVDK 896
Query: 191 GSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGI 250
G PP + + VTVLD +D P F + + + EE + + + ++A D D G
Sbjct: 897 GMPPARTPMEVTVTVLDVNDNPPVFEQDEFDVFV----EENSPIGLAVARVTATDPDEGT 952
Query: 251 NAPLQYSST-GDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATL 309
NA + Y G+ ++ ++ +G++ A L E P +V++AT R AT+
Sbjct: 953 NAQIMYQIVEGNIPEVFQLDIFSGELTALVDLDYEDRPEYVLVIQATSAPLVSR---ATV 1009
Query: 310 XXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVS 369
+ Y T S + PG + VP + L +
Sbjct: 1010 HVRLLDRNDNPPVLGNFEILFNNYVTNRS-SSFPGG---AIGRVPAHDPDISDSLTYSFE 1065
Query: 370 DRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTDSISNDTASINISVEDVNE 425
+ L +N + GE+ L R+LD V+V+D + + TA + V + +
Sbjct: 1066 RGNELSLVLLNASTGELKLSRALDNNRPLEAIMSVLVSDGVHSVTAQCALRVTIITD 1122
Score = 71.7 bits (168), Expect = 1e-11
Identities = 74/340 (21%), Positives = 138/340 (40%), Gaps = 22/340 (6%)
Query: 103 DNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHY---AVLPGPHSEYLGF 159
+ APQ++ Y V E D D+ G L Y A+ +++
Sbjct: 176 NTAPQFQPPSYQATVPENQPAGTPVASLRAIDPDE-GEAGRLEYTMDALFDSRSNQFFSL 234
Query: 160 ENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEH 219
+ + + + LD ET + ++ QD G P + TL + V D +D +P F +
Sbjct: 235 D-PVTGAVTTAEELDRETKSTHVFRVTAQDHGMPRRSALATLTILVTDTNDHDPVFEQQE 293
Query: 220 YTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQY----SSTGDHKQLIVVNKDTGQV 275
Y L ++ E G + T + A D D NA + Y S G ++ ++ +G +
Sbjct: 294 YKESLRENLEVGYEVLT----VRATDGDAPPNANILYRLLEGSGGSPSEVFEIDPRSGVI 349
Query: 276 AATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYST 335
+ E S + ++A+ D +T QF++K+Y
Sbjct: 350 RTRGPVDREEVESYQLTVEASD-QGRDPGPRST--TAAVFLSVEDDNDNAPQFSEKRYVV 406
Query: 336 TVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYE 394
V E +PG+ +L +T ++ + + + + + + +F ++ G + + LDYE
Sbjct: 407 QVREDVTPGAPVLRVTASDRD-KGSNAVVHYSIMSGNARGQFYLDAQTGALDVVSPLDYE 465
Query: 395 TTSNYFYQVMVTDS----ISNDTASINISVEDVNEWEPRF 430
TT Y +V D +SN + + + V D+N+ P F
Sbjct: 466 TTKEYTLRVRAQDGGRPPLSNVSGLVTVQVLDINDNAPIF 505
Score = 69.3 bits (162), Expect = 6e-11
Identities = 73/339 (21%), Positives = 136/339 (40%), Gaps = 19/339 (5%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
+ V V D N + P ++ + Y V V+E +D D G ++ + Y +
Sbjct: 698 IVVNVTDANTHRPVFQSSHYTVNVNEDRPAGTTVVLISATDEDT-GENARITYFM----E 752
Query: 154 SEYLGFENELEP-IIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQN 212
F + + + + LD+E ++T+ + +D G P T L++ V D +D
Sbjct: 753 DSIPQFRIDADTGAVTTQAELDYEDQVSYTLAITARDNGIPQKSDTTYLEILVNDVNDNA 812
Query: 213 PKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTG--DHKQLIVVNK 270
P+F + Y + +D TS ISA D+D G+N + Y+ G D +V
Sbjct: 813 PQFLRDSYQGSVYEDVPP----FTSVLQISATDRDSGLNGRVFYTFQGGDDGDGDFIVES 868
Query: 271 DTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQ 330
+G V ++L + + VL+A VD A + F Q
Sbjct: 869 TSGIVRTLRRL--DRENVAQYVLRAYAVDKGMPPARTPMEVTVTVLDVNDNPPV---FEQ 923
Query: 331 KQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAINN-AGEVILRR 389
++ V E SP + + T E + + + + + + + F ++ +GE+
Sbjct: 924 DEFDVFVEEN-SPIGLAVARVTATDPDEGTNAQIMYQIVEGNIPEVFQLDIFSGELTALV 982
Query: 390 SLDYETTSNYFYQVMVTDSISNDTASINISVEDVNEWEP 428
LDYE Y + T + A++++ + D N+ P
Sbjct: 983 DLDYEDRPEYVLVIQATSAPLVSRATVHVRLLDRNDNPP 1021
>AF234887-1|AAG00080.1| 2923|Homo sapiens FLAMINGO 1 protein.
Length = 2923
Score = 126 bits (303), Expect = 5e-28
Identities = 100/361 (27%), Positives = 163/361 (45%), Gaps = 20/361 (5%)
Query: 81 DRRRTTDP-SFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPG 139
D+ R P S V + V D NDNAPQ+ Y V+V E SDRD+ G
Sbjct: 371 DQGRDPGPRSTTAAVFLSVEDDNDNAPQFSEKRYVVQVREDVTPGAPVLRVTASDRDK-G 429
Query: 140 PHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDT 199
++ +HY+++ G + + + VV PLD+ET +T+++R QD G PPL + +
Sbjct: 430 SNAVVHYSIMSGNARGQFYLDAQTGALDVV-SPLDYETTKEYTLRVRAQDGGRPPLSNVS 488
Query: 200 TL-QVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSS 258
L V VLD +D P F + A + + G + + A D D G NA L+Y
Sbjct: 489 GLVTVQVLDINDNAPIFVSTPFQATVLESVPLGYLVL----HVQAIDADAGDNARLEYRL 544
Query: 259 TG-DHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXX 317
G H +N TG ++ +L E + ++A P A A++
Sbjct: 545 AGVGHDFPFTINNGTGWISVAAELDREEVDFYSFGVEARDHGTPALTASASVSVTVLDVN 604
Query: 318 XXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKF 377
FTQ +Y+ ++E A+ G+ ++T++ V ++ S + + ++ + ++F
Sbjct: 605 DNNPT-----FTQPEYTVRLNEDAAVGTSVVTVSAVDRDA---HSVITYQITSGNTRNRF 656
Query: 378 AI---NNAGEVILRRSLDYETTSNYFYQVMVTDSISNDTASINISVEDVNEWEPRFRHPQ 434
+I + G V L LDY+ Y V +D DTA I ++V D N P F+
Sbjct: 657 SITSQSGGGLVSLALPLDYKLERQYVLAVTASDGTRQDTAQIVVNVTDANTHRPVFQSSH 716
Query: 435 Y 435
Y
Sbjct: 717 Y 717
Score = 103 bits (247), Expect = 3e-21
Identities = 100/436 (22%), Positives = 174/436 (39%), Gaps = 23/436 (5%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
V+V+V D+NDNAP + P+ V E+ D D G ++ L Y L G
Sbjct: 491 VTVQVLDINDNAPIFVSTPFQATVLESVPLGYLVLHVQAIDADA-GDNARLEYR-LAGVG 548
Query: 154 SEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNP 213
++ N I V LD E V+ ++ + +D G+P L + ++ VTVLD +D NP
Sbjct: 549 HDFPFTINNGTGWISVAAELDREEVDFYSFGVEARDHGTPALTASASVSVTVLDVNDNNP 608
Query: 214 KFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKD-T 272
FT YT L +DA GT + T +SA D+D Q +S + + ++
Sbjct: 609 TFTQPEYTVRLNEDAAVGTSVVT----VSAVDRDAHSVITYQITSGNTRNRFSITSQSGG 664
Query: 273 GQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQ 332
G V+ L +L+ + + A+ D + F
Sbjct: 665 GLVSLALPLDYKLERQYVLAVTASDGTRQDTAQIVV--------NVTDANTHRPVFQSSH 716
Query: 333 YSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSL 391
Y+ V+E G+ ++ ++ ++T + + +++ D + +F I+ + G V + L
Sbjct: 717 YTVNVNEDRPAGTTVVLISATDEDTG-ENARITYFMEDS--IPQFRIDADTGAVTTQAEL 773
Query: 392 DYETTSNYFYQVMVTDS---ISNDTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXX 448
DYE +Y + D+ +DT + I V DVN+ P+F Y+
Sbjct: 774 DYEDQVSYTLAITARDNGIPQKSDTTYLEILVNDVNDNAPQFLRDSYQGSVYEDVPPFTS 833
Query: 449 XXXXXXXXXXVAHDGDAGTLALSLAGQHARMFYINASGDLFLREEAIGNLNSSSLHLVAT 508
+G F + ++ + + N + L A
Sbjct: 834 VLQISATDRDSGLNGRV-FYTFQGGDDGDGDFIVESTSGIVRTLRRLDRENVAQYVLRAY 892
Query: 509 AIDSGIPPRQTSVPVT 524
A+D G+PP +T + VT
Sbjct: 893 AVDKGMPPARTPMEVT 908
Score = 85.0 bits (201), Expect = 1e-15
Identities = 93/393 (23%), Positives = 160/393 (40%), Gaps = 22/393 (5%)
Query: 52 PGSKNLTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGA 111
P + +T LDRE K S V S + +++ V D ND+ P +E
Sbjct: 236 PVTGAVTTAEELDRETK---STHVFRVTAQDHGMPRRSALATLTILVTDTNDHDPVFEQQ 292
Query: 112 PYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGP-HSEYLGFE-NELEPIIVV 169
Y + E +D D P P++ + Y +L G S FE + +I
Sbjct: 293 EYKESLRENLEVGYEVLTVRATDGDAP-PNANILYRLLEGSGGSPSEVFEIDPRSGVIRT 351
Query: 170 KKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQV--TVLDADDQNPKFTYEHYTALLPDD 227
+ P+D E V ++ + + DQG P TT V +V D +D P+F+ + Y + +D
Sbjct: 352 RGPVDREEVESYQLTVEASDQGRDPGPRSTTAAVFLSVEDDNDNAPQFSEKRYVVQVRED 411
Query: 228 AEEGTFLTTSPGPISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELD 286
G + ++A+D+D G NA + YS +G+ + ++ TG + L E
Sbjct: 412 VTPGAPVLR----VTASDRDKGSNAVVHYSIMSGNARGQFYLDAQTGALDVVSPLDYETT 467
Query: 287 PSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSV 346
T+ ++A P ++ L F + TV E G +
Sbjct: 468 KEYTLRVRAQDGGRPPLSNVSGLVTVQVLDINDNAPI----FVSTPFQATVLESVPLGYL 523
Query: 347 LLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAINN-AGEVILRRSLDYETTSNYFYQVMV 405
+L + + + + L++ ++ F INN G + + LD E Y + V
Sbjct: 524 VLHVQAIDADAG-DNARLEYRLAGVGHDFPFTINNGTGWISVAAELDREEVDFYSFGVEA 582
Query: 406 TD---SISNDTASINISVEDVNEWEPRFRHPQY 435
D +AS++++V DVN+ P F P+Y
Sbjct: 583 RDHGTPALTASASVSVTVLDVNDNNPTFTQPEY 615
Score = 84.2 bits (199), Expect = 2e-15
Identities = 91/417 (21%), Positives = 166/417 (39%), Gaps = 17/417 (4%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEKIG 70
++ED P G+ + +S + + + IT +++ I + +T LD E+++
Sbjct: 721 VNEDRPAGTTVVLISATDEDTGENARITYFMEDSIPQFRIDADTGAVTTQAELDYEDQVS 780
Query: 71 PSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXX 130
+ + +D +++ + V DVNDNAPQ+ Y V E
Sbjct: 781 YTLAITARDNGIPQKSDTTYL---EILVNDVNDNAPQFLRDSYQGSVYEDVPPFTSVLQI 837
Query: 131 XXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQ 190
+DRD G + + Y G + I+ + LD E V + ++ D+
Sbjct: 838 SATDRDS-GLNGRVFYTFQGGDDGDGDFIVESTSGIVRTLRRLDRENVAQYVLRAYAVDK 896
Query: 191 GSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGI 250
G PP + + VTVLD +D P F + + + EE + + + ++A D D G
Sbjct: 897 GMPPARTPMEVTVTVLDVNDNPPVFEQDEFDVFV----EENSPIGLAVARVTATDPDEGT 952
Query: 251 NAPLQYSST-GDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATL 309
NA + Y G+ ++ ++ +G++ A L E P +V++AT R AT+
Sbjct: 953 NAQIMYQIVEGNIPEVFQLDIFSGELTALVDLDYEDRPEYVLVIQATSAPLVSR---ATV 1009
Query: 310 XXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVS 369
+ Y T S + PG + VP + L +
Sbjct: 1010 HVRLLDRNDNPPVLGNFEILFNNYVTNRS-SSFPGG---AIGRVPAHDPDISDSLTYSFE 1065
Query: 370 DRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTDSISNDTASINISVEDVNE 425
+ L +N + GE+ L R+LD V+V+D + + TA + V + +
Sbjct: 1066 RGNELSLVLLNASTGELKLSRALDNNRPLEAIMSVLVSDGVHSVTAQCALRVTIITD 1122
Score = 71.7 bits (168), Expect = 1e-11
Identities = 74/340 (21%), Positives = 138/340 (40%), Gaps = 22/340 (6%)
Query: 103 DNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHY---AVLPGPHSEYLGF 159
+ APQ++ Y V E D D+ G L Y A+ +++
Sbjct: 176 NTAPQFQPPSYQATVPENQPAGTPVASLRAIDPDE-GEAGRLEYTMDALFDSRSNQFFSL 234
Query: 160 ENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEH 219
+ + + + LD ET + ++ QD G P + TL + V D +D +P F +
Sbjct: 235 D-PVTGAVTTAEELDRETKSTHVFRVTAQDHGMPRRSALATLTILVTDTNDHDPVFEQQE 293
Query: 220 YTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQY----SSTGDHKQLIVVNKDTGQV 275
Y L ++ E G + T + A D D NA + Y S G ++ ++ +G +
Sbjct: 294 YKESLRENLEVGYEVLT----VRATDGDAPPNANILYRLLEGSGGSPSEVFEIDPRSGVI 349
Query: 276 AATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYST 335
+ E S + ++A+ D +T QF++K+Y
Sbjct: 350 RTRGPVDREEVESYQLTVEASD-QGRDPGPRST--TAAVFLSVEDDNDNAPQFSEKRYVV 406
Query: 336 TVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYE 394
V E +PG+ +L +T ++ + + + + + + +F ++ G + + LDYE
Sbjct: 407 QVREDVTPGAPVLRVTASDRD-KGSNAVVHYSIMSGNARGQFYLDAQTGALDVVSPLDYE 465
Query: 395 TTSNYFYQVMVTDS----ISNDTASINISVEDVNEWEPRF 430
TT Y +V D +SN + + + V D+N+ P F
Sbjct: 466 TTKEYTLRVRAQDGGRPPLSNVSGLVTVQVLDINDNAPIF 505
Score = 69.3 bits (162), Expect = 6e-11
Identities = 73/339 (21%), Positives = 136/339 (40%), Gaps = 19/339 (5%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
+ V V D N + P ++ + Y V V+E +D D G ++ + Y +
Sbjct: 698 IVVNVTDANTHRPVFQSSHYTVNVNEDRPAGTTVVLISATDEDT-GENARITYFM----E 752
Query: 154 SEYLGFENELEP-IIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQN 212
F + + + + LD+E ++T+ + +D G P T L++ V D +D
Sbjct: 753 DSIPQFRIDADTGAVTTQAELDYEDQVSYTLAITARDNGIPQKSDTTYLEILVNDVNDNA 812
Query: 213 PKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTG--DHKQLIVVNK 270
P+F + Y + +D TS ISA D+D G+N + Y+ G D +V
Sbjct: 813 PQFLRDSYQGSVYEDVPP----FTSVLQISATDRDSGLNGRVFYTFQGGDDGDGDFIVES 868
Query: 271 DTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQ 330
+G V ++L + + VL+A VD A + F Q
Sbjct: 869 TSGIVRTLRRL--DRENVAQYVLRAYAVDKGMPPARTPMEVTVTVLDVNDNPPV---FEQ 923
Query: 331 KQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAINN-AGEVILRR 389
++ V E SP + + T E + + + + + + + F ++ +GE+
Sbjct: 924 DEFDVFVEEN-SPIGLAVARVTATDPDEGTNAQIMYQIVEGNIPEVFQLDIFSGELTALV 982
Query: 390 SLDYETTSNYFYQVMVTDSISNDTASINISVEDVNEWEP 428
LDYE Y + T + A++++ + D N+ P
Sbjct: 983 DLDYEDRPEYVLVIQATSAPLVSRATVHVRLLDRNDNPP 1021
>AB065955-1|BAC06168.1| 2923|Homo sapiens seven transmembrane helix
receptor protein.
Length = 2923
Score = 126 bits (303), Expect = 5e-28
Identities = 100/361 (27%), Positives = 163/361 (45%), Gaps = 20/361 (5%)
Query: 81 DRRRTTDP-SFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPG 139
D+ R P S V + V D NDNAPQ+ Y V+V E SDRD+ G
Sbjct: 371 DQGRDPGPRSTTAAVFLSVEDDNDNAPQFSEKRYVVQVREDVTPGAPVLRVTASDRDK-G 429
Query: 140 PHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDT 199
++ +HY+++ G + + + VV PLD+ET +T+++R QD G PPL + +
Sbjct: 430 SNAVVHYSIMSGNARGQFYLDAQTGALDVV-SPLDYETTKEYTLRVRAQDGGRPPLSNVS 488
Query: 200 TL-QVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSS 258
L V VLD +D P F + A + + G + + A D D G NA L+Y
Sbjct: 489 GLVTVQVLDINDNAPIFVSTPFQATVLESVPLGYLVL----HVQAIDADAGDNARLEYRL 544
Query: 259 TG-DHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXX 317
G H +N TG ++ +L E + ++A P A A++
Sbjct: 545 AGVGHDFPFTINNGTGWISVAAELDREEVDFYSFGVEARDHGTPALTASASVSVTVLDVN 604
Query: 318 XXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKF 377
FTQ +Y+ ++E A+ G+ ++T++ V ++ S + + ++ + ++F
Sbjct: 605 DNNPT-----FTQPEYTVRLNEDAAVGTSVVTVSAVDRDA---HSVITYQITSGNTRNRF 656
Query: 378 AI---NNAGEVILRRSLDYETTSNYFYQVMVTDSISNDTASINISVEDVNEWEPRFRHPQ 434
+I + G V L LDY+ Y V +D DTA I ++V D N P F+
Sbjct: 657 SITSQSGGGLVSLALPLDYKLERQYVLAVTASDGTRQDTAQIVVNVTDANTHRPVFQSSH 716
Query: 435 Y 435
Y
Sbjct: 717 Y 717
Score = 103 bits (247), Expect = 3e-21
Identities = 100/436 (22%), Positives = 174/436 (39%), Gaps = 23/436 (5%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
V+V+V D+NDNAP + P+ V E+ D D G ++ L Y L G
Sbjct: 491 VTVQVLDINDNAPIFVSTPFQATVLESVPLGYLVLHVQAIDADA-GDNARLEYR-LAGVG 548
Query: 154 SEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNP 213
++ N I V LD E V+ ++ + +D G+P L + ++ VTVLD +D NP
Sbjct: 549 HDFPFTINNGTGWISVAAELDREEVDFYSFGVEARDHGTPALTASASVSVTVLDVNDNNP 608
Query: 214 KFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKD-T 272
FT YT L +DA GT + T +SA D+D Q +S + + ++
Sbjct: 609 TFTQPEYTVRLNEDAAVGTSVVT----VSAVDRDAHSVITYQITSGNTRNRFSITSQSGG 664
Query: 273 GQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQ 332
G V+ L +L+ + + A+ D + F
Sbjct: 665 GLVSLALPLDYKLERQYVLAVTASDGTRQDTAQIVV--------NVTDANTHRPVFQSSH 716
Query: 333 YSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSL 391
Y+ V+E G+ ++ ++ ++T + + +++ D + +F I+ + G V + L
Sbjct: 717 YTVNVNEDRPAGTTVVLISATDEDTG-ENARITYFMEDS--IPQFRIDADTGAVTTQAEL 773
Query: 392 DYETTSNYFYQVMVTDS---ISNDTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXX 448
DYE +Y + D+ +DT + I V DVN+ P+F Y+
Sbjct: 774 DYEDQVSYTLAITARDNGIPQKSDTTYLEILVNDVNDNAPQFLRDSYQGSVYEDVPPFTS 833
Query: 449 XXXXXXXXXXVAHDGDAGTLALSLAGQHARMFYINASGDLFLREEAIGNLNSSSLHLVAT 508
+G F + ++ + + N + L A
Sbjct: 834 VLQISATDRDSGLNGRV-FYTFQGGDDGDGDFIVESTSGIVRTLRRLDRENVAQYVLRAY 892
Query: 509 AIDSGIPPRQTSVPVT 524
A+D G+PP +T + VT
Sbjct: 893 AVDKGMPPARTPMEVT 908
Score = 85.0 bits (201), Expect = 1e-15
Identities = 93/393 (23%), Positives = 160/393 (40%), Gaps = 22/393 (5%)
Query: 52 PGSKNLTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGA 111
P + +T LDRE K S V S + +++ V D ND+ P +E
Sbjct: 236 PVTGAVTTAEELDRETK---STHVFRVTAQDHGMPRRSALATLTILVTDTNDHDPVFEQQ 292
Query: 112 PYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGP-HSEYLGFE-NELEPIIVV 169
Y + E +D D P P++ + Y +L G S FE + +I
Sbjct: 293 EYKESLRENLEVGYEVLTVRATDGDAP-PNANILYRLLEGSGGSPSEVFEIDPRSGVIRT 351
Query: 170 KKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQV--TVLDADDQNPKFTYEHYTALLPDD 227
+ P+D E V ++ + + DQG P TT V +V D +D P+F+ + Y + +D
Sbjct: 352 RGPVDREEVESYQLTVEASDQGRDPGPRSTTAAVFLSVEDDNDNAPQFSEKRYVVQVRED 411
Query: 228 AEEGTFLTTSPGPISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELD 286
G + ++A+D+D G NA + YS +G+ + ++ TG + L E
Sbjct: 412 VTPGAPVLR----VTASDRDKGSNAVVHYSIMSGNARGQFYLDAQTGALDVVSPLDYETT 467
Query: 287 PSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSV 346
T+ ++A P ++ L F + TV E G +
Sbjct: 468 KEYTLRVRAQDGGRPPLSNVSGLVTVQVLDINDNAPI----FVSTPFQATVLESVPLGYL 523
Query: 347 LLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAINN-AGEVILRRSLDYETTSNYFYQVMV 405
+L + + + + L++ ++ F INN G + + LD E Y + V
Sbjct: 524 VLHVQAIDADAG-DNARLEYRLAGVGHDFPFTINNGTGWISVAAELDREEVDFYSFGVEA 582
Query: 406 TD---SISNDTASINISVEDVNEWEPRFRHPQY 435
D +AS++++V DVN+ P F P+Y
Sbjct: 583 RDHGTPALTASASVSVTVLDVNDNNPTFTQPEY 615
Score = 84.2 bits (199), Expect = 2e-15
Identities = 91/417 (21%), Positives = 166/417 (39%), Gaps = 17/417 (4%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEKIG 70
++ED P G+ + +S + + + IT +++ I + +T LD E+++
Sbjct: 721 VNEDRPAGTTVVLISATDEDTGENARITYFMEDSIPQFRIDADTGAVTTQAELDYEDQVS 780
Query: 71 PSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXX 130
+ + +D +++ + V DVNDNAPQ+ Y V E
Sbjct: 781 YTLAITARDNGIPQKSDTTYL---EILVNDVNDNAPQFLRDSYQGSVYEDVPPFTSVLQI 837
Query: 131 XXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQ 190
+DRD G + + Y G + I+ + LD E V + ++ D+
Sbjct: 838 SATDRDS-GLNGRVFYTFQGGDDGDGDFIVESTSGIVRTLRRLDRENVAQYVLRAYAVDK 896
Query: 191 GSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGI 250
G PP + + VTVLD +D P F + + + EE + + + ++A D D G
Sbjct: 897 GMPPARTPMEVTVTVLDVNDNPPVFEQDEFDVFV----EENSPIGLAVARVTATDPDEGT 952
Query: 251 NAPLQYSST-GDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATL 309
NA + Y G+ ++ ++ +G++ A L E P +V++AT R AT+
Sbjct: 953 NAQIMYQIVEGNIPEVFQLDIFSGELTALVDLDYEDRPEYVLVIQATSAPLVSR---ATV 1009
Query: 310 XXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVS 369
+ Y T S + PG + VP + L +
Sbjct: 1010 HVRLLDRNDNPPVLGNFEILFNNYVTNRS-SSFPGG---AIGRVPAHDPDISDSLTYSFE 1065
Query: 370 DRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTDSISNDTASINISVEDVNE 425
+ L +N + GE+ L R+LD V+V+D + + TA + V + +
Sbjct: 1066 RGNELSLVLLNASTGELKLSRALDNNRPLEAIMSVLVSDGVHSVTAQCALRVTIITD 1122
Score = 71.7 bits (168), Expect = 1e-11
Identities = 74/340 (21%), Positives = 138/340 (40%), Gaps = 22/340 (6%)
Query: 103 DNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHY---AVLPGPHSEYLGF 159
+ APQ++ Y V E D D+ G L Y A+ +++
Sbjct: 176 NTAPQFQPPSYQATVPENQPAGTPVASLRAIDPDE-GEAGRLEYTMDALFDSRSNQFFSL 234
Query: 160 ENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEH 219
+ + + + LD ET + ++ QD G P + TL + V D +D +P F +
Sbjct: 235 D-PVTGAVTTAEELDRETKSTHVFRVTAQDHGMPRRSALATLTILVTDTNDHDPVFEQQE 293
Query: 220 YTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQY----SSTGDHKQLIVVNKDTGQV 275
Y L ++ E G + T + A D D NA + Y S G ++ ++ +G +
Sbjct: 294 YKESLRENLEVGYEVLT----VRATDGDAPPNANILYRLLEGSGGSPSEVFEIDPRSGVI 349
Query: 276 AATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYST 335
+ E S + ++A+ D +T QF++K+Y
Sbjct: 350 RTRGPVDREEVESYQLTVEASD-QGRDPGPRST--TAAVFLSVEDDNDNAPQFSEKRYVV 406
Query: 336 TVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYE 394
V E +PG+ +L +T ++ + + + + + + +F ++ G + + LDYE
Sbjct: 407 QVREDVTPGAPVLRVTASDRD-KGSNAVVHYSIMSGNARGQFYLDAQTGALDVVSPLDYE 465
Query: 395 TTSNYFYQVMVTDS----ISNDTASINISVEDVNEWEPRF 430
TT Y +V D +SN + + + V D+N+ P F
Sbjct: 466 TTKEYTLRVRAQDGGRPPLSNVSGLVTVQVLDINDNAPIF 505
Score = 69.3 bits (162), Expect = 6e-11
Identities = 73/339 (21%), Positives = 136/339 (40%), Gaps = 19/339 (5%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
+ V V D N + P ++ + Y V V+E +D D G ++ + Y +
Sbjct: 698 IVVNVTDANTHRPVFQSSHYTVNVNEDRPAGTTVVLISATDEDT-GENARITYFM----E 752
Query: 154 SEYLGFENELEP-IIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQN 212
F + + + + LD+E ++T+ + +D G P T L++ V D +D
Sbjct: 753 DSIPQFRIDADTGAVTTQAELDYEDQVSYTLAITARDNGIPQKSDTTYLEILVNDVNDNA 812
Query: 213 PKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTG--DHKQLIVVNK 270
P+F + Y + +D TS ISA D+D G+N + Y+ G D +V
Sbjct: 813 PQFLRDSYQGSVYEDVPP----FTSVLQISATDRDSGLNGRVFYTFQGGDDGDGDFIVES 868
Query: 271 DTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQ 330
+G V ++L + + VL+A VD A + F Q
Sbjct: 869 TSGIVRTLRRL--DRENVAQYVLRAYAVDKGMPPARTPMEVTVTVLDVNDNPPV---FEQ 923
Query: 331 KQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAINN-AGEVILRR 389
++ V E SP + + T E + + + + + + + F ++ +GE+
Sbjct: 924 DEFDVFVEEN-SPIGLAVARVTATDPDEGTNAQIMYQIVEGNIPEVFQLDIFSGELTALV 982
Query: 390 SLDYETTSNYFYQVMVTDSISNDTASINISVEDVNEWEP 428
LDYE Y + T + A++++ + D N+ P
Sbjct: 983 DLDYEDRPEYVLVIQATSAPLVSRATVHVRLLDRNDNPP 1021
>AY714129-1|AAU94938.1| 4186|Homo sapiens anchor protein protein.
Length = 4186
Score = 118 bits (285), Expect = 7e-26
Identities = 122/480 (25%), Positives = 200/480 (41%), Gaps = 30/480 (6%)
Query: 46 AAVGIVPGSKNLTLLRALDREEKIGPSNVYVNVRCDRRRTTDP-SFVIPVSVRVWDVNDN 104
AA I P S ++ +DRE S V D+ + P S + V + V D NDN
Sbjct: 554 AAFEIDPRSGLISTSGRVDREHM--ESYELVVEASDQGQEPGPRSATVRVHITVLDENDN 611
Query: 105 APQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELE 164
APQ+ Y +V E +DRD+ + +HY ++ G + ++
Sbjct: 612 APQFSEKRYVAQVREDVRPHTVVLRVTATDRDKDA-NGLVHYNIISGNSRGHFAIDSLTG 670
Query: 165 PIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTL-QVTVLDADDQNPKFTYEHYTAL 223
I VV PLDFE + +++R QD G PPL ++T L + V+D +D P F +
Sbjct: 671 EIQVVA-PLDFEAEREYALRIRAQDAGRPPLSNNTGLASIQVVDINDHIPIFVSTPFQVS 729
Query: 224 LPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQL-IVVNKDTGQVAATKQLI 282
+ ++A G S I A D D G NA L+YS TG V+N TG V+ + L
Sbjct: 730 VLENAPLG----HSVIHIQAVDADHGENARLEYSLTGVAPDTPFVINSATGWVSVSGPLD 785
Query: 283 AELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGAS 342
E ++A +P A A++ +FT K+Y ++E A+
Sbjct: 786 RESVEHYFFGVEARDHGSPPLSASASVTVTVLDVNDNRP-----EFTMKEYHLRLNEDAA 840
Query: 343 PGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAIN---NAGEVILRRSLDYETTSNY 399
G+ ++++T V ++ S + + ++ + ++FAI+ G V L LDY+ +
Sbjct: 841 VGTSVVSVTAVDRDA---NSAISYQITGGNTRNRFAISTQGGVGLVTLALPLDYKQERYF 897
Query: 400 FYQVMVTDSISNDTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXV 459
+ +D +D ++I++ D N P F+ Y
Sbjct: 898 KLVLTASDRALHDHCYVHINITDANTHRPVFQSAHYSVSVNEDRPMGSTIVVIS------ 951
Query: 460 AHDGDAGTLA--LSLAGQHARMFYINASGDLFLREEAIGNLNSSSLHLVATAIDSGIPPR 517
A D D G A L + F I+A + + + + L TA D+GIP +
Sbjct: 952 ASDDDVGENARITYLLEDNLPQFRIDADSGAITLQAPLDYEDQVTYTLAITARDNGIPQK 1011
Score = 89.8 bits (213), Expect = 4e-17
Identities = 104/421 (24%), Positives = 170/421 (40%), Gaps = 19/421 (4%)
Query: 8 SFFISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREE 67
S ++ED P+GS I +S + D + IT L++ I S +TL LD E+
Sbjct: 934 SVSVNEDRPMGSTIVVISASDDDVGENARITYLLEDNLPQFRIDADSGAITLQAPLDYED 993
Query: 68 KIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXX 127
++ + + D ++V V V DVNDNAPQ+ + Y VSE
Sbjct: 994 QVTYTLAITARDNGIPQKADTTYV---EVMVNDVNDNAPQFVASHYTGLVSEDAPPFTSV 1050
Query: 128 XXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRV 187
+DRD + + Y G + I+ + LD E V+ + +
Sbjct: 1051 LQISATDRDAHA-NGRVQYTFQNGEDGDGDFTIEPTSGIVRTVRRLDREAVSVYELTAYA 1109
Query: 188 QDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQD 247
D+G PPL + ++QV V D +D P F E + + +++ G+ + I+A D D
Sbjct: 1110 VDRGVPPLRTPVSIQVMVQDVNDNAPVFPAEEFEVRVKENSIVGSVV----AQITAVDPD 1165
Query: 248 LGINAPLQYSST-GDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYAL 306
G NA + Y G+ +L ++ +G++ A L E IV++AT R
Sbjct: 1166 EGPNAHIMYQIVEGNIPELFQMDIFSGELTALIDLDYEARQEYVIVVQATSAPLVSR--- 1222
Query: 307 ATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQF 366
AT+ Q Y + S+ P ++ + + S F
Sbjct: 1223 ATVHVRLVDQNDNSPVLNNFQILFNNYVSNRSD-TFPSGIIGRIPAYDPDV----SDHLF 1277
Query: 367 YVSDR-SFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTDSISNDTASINISVEDVN 424
Y +R + L +N +GE+ L R LD V VTD + + TA + V +
Sbjct: 1278 YSFERGNELQLLVVNQTSGELRLSRKLDNNRPLVASMLVTVTDGLHSVTAQCVLRVVIIT 1337
Query: 425 E 425
E
Sbjct: 1338 E 1338
Score = 86.6 bits (205), Expect = 3e-16
Identities = 94/397 (23%), Positives = 167/397 (42%), Gaps = 24/397 (6%)
Query: 50 IVPGSKNLTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWE 109
I P S + ALDRE Y+ V + S V+V V D ND++P +E
Sbjct: 448 IDPQSGLIRTAAALDRESM---ERHYLRVTAQDHGSPRLSATTMVAVTVADRNDHSPVFE 504
Query: 110 GAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFEN-ELEP--- 165
A Y + E +D D P P++ L Y + P + E++P
Sbjct: 505 QAQYRETLRENVEEGYPILQLRATDGDAP-PNANLRYRFVGPPAARAAAAAAFEIDPRSG 563
Query: 166 IIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQV--TVLDADDQNPKFTYEHYTAL 223
+I +D E + ++ + + DQG P T++V TVLD +D P+F+ + Y A
Sbjct: 564 LISTSGRVDREHMESYELVVEASDQGQEPGPRSATVRVHITVLDENDNAPQFSEKRYVAQ 623
Query: 224 LPDDAEEGTFLTTSPGPISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLI 282
+ +D T + ++A D+D N + Y+ +G+ + ++ TG++ L
Sbjct: 624 VREDVRPHTVVLR----VTATDRDKDANGLVHYNIISGNSRGHFAIDSLTGEIQVVAPLD 679
Query: 283 AELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGAS 342
E + + ++A P L+ + F + +V E A
Sbjct: 680 FEAEREYALRIRAQDAGRP---PLSNNTGLASIQVVDINDHIPI-FVSTPFQVSVLENAP 735
Query: 343 PGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAINNA-GEVILRRSLDYETTSNYFY 401
G ++ + V + + L++ ++ + F IN+A G V + LD E+ +YF+
Sbjct: 736 LGHSVIHIQAVDAD-HGENARLEYSLTGVAPDTPFVINSATGWVSVSGPLDRESVEHYFF 794
Query: 402 QVMVTDSIS---NDTASINISVEDVNEWEPRFRHPQY 435
V D S + +AS+ ++V DVN+ P F +Y
Sbjct: 795 GVEARDHGSPPLSASASVTVTVLDVNDNRPEFTMKEY 831
Score = 83.8 bits (198), Expect = 2e-15
Identities = 80/346 (23%), Positives = 141/346 (40%), Gaps = 15/346 (4%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
V + + D N + P ++ A Y+V V+E SD D G ++ + Y +
Sbjct: 914 VHINITDANTHRPVFQSAHYSVSVNEDRPMGSTIVVISASD-DDVGENARITYLLEDNLP 972
Query: 154 SEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNP 213
+ ++ I ++ PLD+E +T+ + +D G P T ++V V D +D P
Sbjct: 973 QFRIDADSGA---ITLQAPLDYEDQVTYTLAITARDNGIPQKADTTYVEVMVNDVNDNAP 1029
Query: 214 KFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYS-STGDHKQLIVVNKDT 272
+F HYT L+ +DA TS ISA D+D N +QY+ G+ + T
Sbjct: 1030 QFVASHYTGLVSEDAPP----FTSVLQISATDRDAHANGRVQYTFQNGEDGDGDFTIEPT 1085
Query: 273 GQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQ 332
+ T + LD V + T DR F ++
Sbjct: 1086 SGIVRT---VRRLDREAVSVYELTAYA-VDRGVPPLRTPVSIQVMVQDVNDNAPVFPAEE 1141
Query: 333 YSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAINN-AGEVILRRSL 391
+ V E + GSV+ +T V + E + + + + + + + F ++ +GE+ L
Sbjct: 1142 FEVRVKENSIVGSVVAQITAVDPD-EGPNAHIMYQIVEGNIPELFQMDIFSGELTALIDL 1200
Query: 392 DYETTSNYFYQVMVTDSISNDTASINISVEDVNEWEPRFRHPQYEF 437
DYE Y V T + A++++ + D N+ P + Q F
Sbjct: 1201 DYEARQEYVIVVQATSAPLVSRATVHVRLVDQNDNSPVLNNFQILF 1246
Score = 82.6 bits (195), Expect = 6e-15
Identities = 88/350 (25%), Positives = 137/350 (39%), Gaps = 23/350 (6%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
V+V V DVNDN P++ Y +R++E DRD +SA+ Y + G
Sbjct: 812 VTVTVLDVNDNRPEFTMKEYHLRLNEDAAVGTSVVSVTAVDRDA---NSAISYQITGGNT 868
Query: 154 SEYLGFENELEP-IIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQN 212
+ ++ + PLD++ F + L D+ L+ + + + DA+
Sbjct: 869 RNRFAISTQGGVGLVTLALPLDYKQERYFKLVLTASDRA---LHDHCYVHINITDANTHR 925
Query: 213 PKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDT 272
P F HY+ + +D G+ + ISA+D D+G NA + Y D+ ++ D+
Sbjct: 926 PVFQSAHYSVSVNEDRPMGSTIVV----ISASDDDVGENARITYLLE-DNLPQFRIDADS 980
Query: 273 GQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQ 332
G A T Q + + VT L T DN T QF
Sbjct: 981 G--AITLQAPLDYEDQVTYTLAITARDNGIPQKADTTYVEVMVNDVNDNAP---QFVASH 1035
Query: 333 YSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSL 391
Y+ VSE A P + +L ++ ++ + + F I +G V R L
Sbjct: 1036 YTGLVSEDAPPFTSVLQISATDRDAHANGRVQYTFQNGEDGDGDFTIEPTSGIVRTVRRL 1095
Query: 392 DYETTSNYFYQVMVTDS---ISNDTASINISVEDVNEWEPRFRHPQYEFE 438
D E S Y D SI + V+DVN+ P F P EFE
Sbjct: 1096 DREAVSVYELTAYAVDRGVPPLRTPVSIQVMVQDVNDNAPVF--PAEEFE 1143
Score = 75.4 bits (177), Expect = 9e-13
Identities = 81/338 (23%), Positives = 137/338 (40%), Gaps = 22/338 (6%)
Query: 106 PQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHY--AVLPGPHSEYLGFENEL 163
PQ+ Y V E D D G L Y A L S L +
Sbjct: 393 PQFPQYNYQTLVPENEAAGTAVLRVVAQDPDA-GEAGRLVYSLAALMNSRSLELFSIDPQ 451
Query: 164 EPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTAL 223
+I LD E++ +++ QD GSP L + T + VTV D +D +P F Y
Sbjct: 452 SGLIRTAAALDRESMERHYLRVTAQDHGSPRLSATTMVAVTVADRNDHSPVFEQAQYRET 511
Query: 224 LPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGD------HKQLIVVNKDTGQVAA 277
L ++ EEG + + A D D NA L+Y G ++ +G ++
Sbjct: 512 LRENVEEGYPIL----QLRATDGDAPPNANLRYRFVGPPAARAAAAAAFEIDPRSGLIST 567
Query: 278 TKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTV 337
+ ++ E S +V++A+ AT+ QF++K+Y V
Sbjct: 568 SGRVDREHMESYELVVEASDQGQEPGPRSATVRVHITVLDENDNAP---QFSEKRYVAQV 624
Query: 338 SEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAINN-AGEVILRRSLDYETT 396
E P +V+L +T ++ + + + + + FAI++ GE+ + LD+E
Sbjct: 625 REDVRPHTVVLRVTATDRDKD-ANGLVHYNIISGNSRGHFAIDSLTGEIQVVAPLDFEAE 683
Query: 397 SNYFYQVMVTDS----ISNDTASINISVEDVNEWEPRF 430
Y ++ D+ +SN+T +I V D+N+ P F
Sbjct: 684 REYALRIRAQDAGRPPLSNNTGLASIQVVDINDHIPIF 721
>AF231023-1|AAF61929.1| 3312|Homo sapiens protocadherin Flamingo 1
protein.
Length = 3312
Score = 118 bits (285), Expect = 7e-26
Identities = 122/480 (25%), Positives = 200/480 (41%), Gaps = 30/480 (6%)
Query: 46 AAVGIVPGSKNLTLLRALDREEKIGPSNVYVNVRCDRRRTTDP-SFVIPVSVRVWDVNDN 104
AA I P S ++ +DRE S V D+ + P S + V + V D NDN
Sbjct: 484 AAFEIDPRSGLISTSGRVDREHM--ESYELVVEASDQGQEPGPRSATVRVHITVLDENDN 541
Query: 105 APQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELE 164
APQ+ Y +V E +DRD+ + +HY ++ G + ++
Sbjct: 542 APQFSEKRYVAQVREDVRPHTVVLRVTATDRDKDA-NGLVHYNIISGNSRGHFAIDSLTG 600
Query: 165 PIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTL-QVTVLDADDQNPKFTYEHYTAL 223
I VV PLDFE + +++R QD G PPL ++T L + V+D +D P F +
Sbjct: 601 EIQVVA-PLDFEAEREYALRIRAQDAGRPPLSNNTGLASIQVVDINDHIPIFVSTPFQVS 659
Query: 224 LPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQL-IVVNKDTGQVAATKQLI 282
+ ++A G S I A D D G NA L+YS TG V+N TG V+ + L
Sbjct: 660 VLENAPLG----HSVIHIQAVDADHGENARLEYSLTGVAPDTPFVINSATGWVSVSGPLD 715
Query: 283 AELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGAS 342
E ++A +P A A++ +FT K+Y ++E A+
Sbjct: 716 RESVEHYFFGVEARDHGSPPLSASASVTVTVLDVNDNRP-----EFTMKEYHLRLNEDAA 770
Query: 343 PGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAIN---NAGEVILRRSLDYETTSNY 399
G+ ++++T V ++ S + + ++ + ++FAI+ G V L LDY+ +
Sbjct: 771 VGTSVVSVTAVDRDA---NSAISYQITGGNTRNRFAISTQGGVGLVTLALPLDYKQERYF 827
Query: 400 FYQVMVTDSISNDTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXV 459
+ +D +D ++I++ D N P F+ Y
Sbjct: 828 KLVLTASDRALHDHCYVHINITDANTHRPVFQSAHYSVSVNEDRPMGSTIVVIS------ 881
Query: 460 AHDGDAGTLA--LSLAGQHARMFYINASGDLFLREEAIGNLNSSSLHLVATAIDSGIPPR 517
A D D G A L + F I+A + + + + L TA D+GIP +
Sbjct: 882 ASDDDVGENARITYLLEDNLPQFRIDADSGAITLQAPLDYEDQVTYTLAITARDNGIPQK 941
Score = 89.8 bits (213), Expect = 4e-17
Identities = 104/421 (24%), Positives = 170/421 (40%), Gaps = 19/421 (4%)
Query: 8 SFFISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREE 67
S ++ED P+GS I +S + D + IT L++ I S +TL LD E+
Sbjct: 864 SVSVNEDRPMGSTIVVISASDDDVGENARITYLLEDNLPQFRIDADSGAITLQAPLDYED 923
Query: 68 KIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXX 127
++ + + D ++V V V DVNDNAPQ+ + Y VSE
Sbjct: 924 QVTYTLAITARDNGIPQKADTTYV---EVMVNDVNDNAPQFVASHYTGLVSEDAPPFTSV 980
Query: 128 XXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRV 187
+DRD + + Y G + I+ + LD E V+ + +
Sbjct: 981 LQISATDRDAHA-NGRVQYTFQNGEDGDGDFTIEPTSGIVRTVRRLDREAVSVYELTAYA 1039
Query: 188 QDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQD 247
D+G PPL + ++QV V D +D P F E + + +++ G+ + I+A D D
Sbjct: 1040 VDRGVPPLRTPVSIQVMVQDVNDNAPVFPAEEFEVRVKENSIVGSVV----AQITAVDPD 1095
Query: 248 LGINAPLQYSST-GDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYAL 306
G NA + Y G+ +L ++ +G++ A L E IV++AT R
Sbjct: 1096 EGPNAHIMYQIVEGNIPELFQMDIFSGELTALIDLDYEARQEYVIVVQATSAPLVSR--- 1152
Query: 307 ATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQF 366
AT+ Q Y + S+ P ++ + + S F
Sbjct: 1153 ATVHVRLVDQNDNSPVLNNFQILFNNYVSNRSD-TFPSGIIGRIPAYDPDV----SDHLF 1207
Query: 367 YVSDR-SFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTDSISNDTASINISVEDVN 424
Y +R + L +N +GE+ L R LD V VTD + + TA + V +
Sbjct: 1208 YSFERGNELQLLVVNQTSGELRLSRKLDNNRPLVASMLVTVTDGLHSVTAQCVLRVVIIT 1267
Query: 425 E 425
E
Sbjct: 1268 E 1268
Score = 86.6 bits (205), Expect = 3e-16
Identities = 94/397 (23%), Positives = 167/397 (42%), Gaps = 24/397 (6%)
Query: 50 IVPGSKNLTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWE 109
I P S + ALDRE Y+ V + S V+V V D ND++P +E
Sbjct: 378 IDPQSGLIRTAAALDRESM---ERHYLRVTAQDHGSPRLSATTMVAVTVADRNDHSPVFE 434
Query: 110 GAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFEN-ELEP--- 165
A Y + E +D D P P++ L Y + P + E++P
Sbjct: 435 QAQYRETLRENVEEGYPILQLRATDGDAP-PNANLRYRFVGPPAARAAAAAAFEIDPRSG 493
Query: 166 IIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQV--TVLDADDQNPKFTYEHYTAL 223
+I +D E + ++ + + DQG P T++V TVLD +D P+F+ + Y A
Sbjct: 494 LISTSGRVDREHMESYELVVEASDQGQEPGPRSATVRVHITVLDENDNAPQFSEKRYVAQ 553
Query: 224 LPDDAEEGTFLTTSPGPISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLI 282
+ +D T + ++A D+D N + Y+ +G+ + ++ TG++ L
Sbjct: 554 VREDVRPHTVVLR----VTATDRDKDANGLVHYNIISGNSRGHFAIDSLTGEIQVVAPLD 609
Query: 283 AELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGAS 342
E + + ++A P L+ + F + +V E A
Sbjct: 610 FEAEREYALRIRAQDAGRP---PLSNNTGLASIQVVDINDHIPI-FVSTPFQVSVLENAP 665
Query: 343 PGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAINNA-GEVILRRSLDYETTSNYFY 401
G ++ + V + + L++ ++ + F IN+A G V + LD E+ +YF+
Sbjct: 666 LGHSVIHIQAVDAD-HGENARLEYSLTGVAPDTPFVINSATGWVSVSGPLDRESVEHYFF 724
Query: 402 QVMVTDSIS---NDTASINISVEDVNEWEPRFRHPQY 435
V D S + +AS+ ++V DVN+ P F +Y
Sbjct: 725 GVEARDHGSPPLSASASVTVTVLDVNDNRPEFTMKEY 761
Score = 83.8 bits (198), Expect = 2e-15
Identities = 80/346 (23%), Positives = 141/346 (40%), Gaps = 15/346 (4%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
V + + D N + P ++ A Y+V V+E SD D G ++ + Y +
Sbjct: 844 VHINITDANTHRPVFQSAHYSVSVNEDRPMGSTIVVISASD-DDVGENARITYLLEDNLP 902
Query: 154 SEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNP 213
+ ++ I ++ PLD+E +T+ + +D G P T ++V V D +D P
Sbjct: 903 QFRIDADSGA---ITLQAPLDYEDQVTYTLAITARDNGIPQKADTTYVEVMVNDVNDNAP 959
Query: 214 KFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYS-STGDHKQLIVVNKDT 272
+F HYT L+ +DA TS ISA D+D N +QY+ G+ + T
Sbjct: 960 QFVASHYTGLVSEDAPP----FTSVLQISATDRDAHANGRVQYTFQNGEDGDGDFTIEPT 1015
Query: 273 GQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQ 332
+ T + LD V + T DR F ++
Sbjct: 1016 SGIVRT---VRRLDREAVSVYELTAYA-VDRGVPPLRTPVSIQVMVQDVNDNAPVFPAEE 1071
Query: 333 YSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAINN-AGEVILRRSL 391
+ V E + GSV+ +T V + E + + + + + + + F ++ +GE+ L
Sbjct: 1072 FEVRVKENSIVGSVVAQITAVDPD-EGPNAHIMYQIVEGNIPELFQMDIFSGELTALIDL 1130
Query: 392 DYETTSNYFYQVMVTDSISNDTASINISVEDVNEWEPRFRHPQYEF 437
DYE Y V T + A++++ + D N+ P + Q F
Sbjct: 1131 DYEARQEYVIVVQATSAPLVSRATVHVRLVDQNDNSPVLNNFQILF 1176
Score = 82.6 bits (195), Expect = 6e-15
Identities = 88/350 (25%), Positives = 137/350 (39%), Gaps = 23/350 (6%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
V+V V DVNDN P++ Y +R++E DRD +SA+ Y + G
Sbjct: 742 VTVTVLDVNDNRPEFTMKEYHLRLNEDAAVGTSVVSVTAVDRDA---NSAISYQITGGNT 798
Query: 154 SEYLGFENELEP-IIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQN 212
+ ++ + PLD++ F + L D+ L+ + + + DA+
Sbjct: 799 RNRFAISTQGGVGLVTLALPLDYKQERYFKLVLTASDRA---LHDHCYVHINITDANTHR 855
Query: 213 PKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDT 272
P F HY+ + +D G+ + ISA+D D+G NA + Y D+ ++ D+
Sbjct: 856 PVFQSAHYSVSVNEDRPMGSTIVV----ISASDDDVGENARITYLLE-DNLPQFRIDADS 910
Query: 273 GQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQ 332
G A T Q + + VT L T DN T QF
Sbjct: 911 G--AITLQAPLDYEDQVTYTLAITARDNGIPQKADTTYVEVMVNDVNDNAP---QFVASH 965
Query: 333 YSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSL 391
Y+ VSE A P + +L ++ ++ + + F I +G V R L
Sbjct: 966 YTGLVSEDAPPFTSVLQISATDRDAHANGRVQYTFQNGEDGDGDFTIEPTSGIVRTVRRL 1025
Query: 392 DYETTSNYFYQVMVTDS---ISNDTASINISVEDVNEWEPRFRHPQYEFE 438
D E S Y D SI + V+DVN+ P F P EFE
Sbjct: 1026 DREAVSVYELTAYAVDRGVPPLRTPVSIQVMVQDVNDNAPVF--PAEEFE 1073
Score = 75.4 bits (177), Expect = 9e-13
Identities = 81/338 (23%), Positives = 137/338 (40%), Gaps = 22/338 (6%)
Query: 106 PQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHY--AVLPGPHSEYLGFENEL 163
PQ+ Y V E D D G L Y A L S L +
Sbjct: 323 PQFPQYNYQTLVPENEAAGTAVLRVVAQDPDA-GEAGRLVYSLAALMNSRSLELFSIDPQ 381
Query: 164 EPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTAL 223
+I LD E++ +++ QD GSP L + T + VTV D +D +P F Y
Sbjct: 382 SGLIRTAAALDRESMERHYLRVTAQDHGSPRLSATTMVAVTVADRNDHSPVFEQAQYRET 441
Query: 224 LPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGD------HKQLIVVNKDTGQVAA 277
L ++ EEG + + A D D NA L+Y G ++ +G ++
Sbjct: 442 LRENVEEGYPIL----QLRATDGDAPPNANLRYRFVGPPAARAAAAAAFEIDPRSGLIST 497
Query: 278 TKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTV 337
+ ++ E S +V++A+ AT+ QF++K+Y V
Sbjct: 498 SGRVDREHMESYELVVEASDQGQEPGPRSATVRVHITVLDENDNAP---QFSEKRYVAQV 554
Query: 338 SEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAINN-AGEVILRRSLDYETT 396
E P +V+L +T ++ + + + + + FAI++ GE+ + LD+E
Sbjct: 555 REDVRPHTVVLRVTATDRDKD-ANGLVHYNIISGNSRGHFAIDSLTGEIQVVAPLDFEAE 613
Query: 397 SNYFYQVMVTDS----ISNDTASINISVEDVNEWEPRF 430
Y ++ D+ +SN+T +I V D+N+ P F
Sbjct: 614 REYALRIRAQDAGRPPLSNNTGLASIQVVDINDHIPIF 651
>AY356402-1|AAR13653.1| 3222|Homo sapiens fat-like cadherin FATJ
protein protein.
Length = 3222
Score = 113 bits (272), Expect = 3e-24
Identities = 134/525 (25%), Positives = 213/525 (40%), Gaps = 37/525 (7%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKN--LTLLRALDREEK 68
+ E+ P+GS + +V D + + G ++G KN L +L+ALDRE +
Sbjct: 251 LMENLPVGSTVLVFNVT-DADDGINSQLTYSIASGDSLGQFTVDKNGVLKVLKALDRESQ 309
Query: 69 IGPSNVYVNVRCDRRRTTDPSFV--IPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXX 126
N+ V V D + F VS+ + DVNDN P + +P + E
Sbjct: 310 -SFYNLVVQVH-DLPQIPASRFTSTAQVSIILLDVNDNPPTFL-SPKLTYIPENTPIDTV 366
Query: 127 XXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLR 186
+D D GP+S + Y +L P ++ + + LD E V+N+T+ +
Sbjct: 367 VFKAQATDPDS-GPNSYIEYTLL-NPLGNKFSI-GTIDGEVRLTGELDREEVSNYTLTVV 423
Query: 187 VQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQ 246
D+G P L S T + V VLD +D NP F AL + E T T + AAD
Sbjct: 424 ATDKGQPSLSSSTEVVVMVLDINDNNPIFA----QALYKVEINENTLTGTDIIQVFAADG 479
Query: 247 DLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYA 305
D G N ++Y G+ Q ++ TG + K L E P+ + ++AT + R
Sbjct: 480 DEGTNGQVRYGIVNGNTNQEFRIDSVTGAITVAKPLDREKTPTYHLTVQATDRGSTPRTD 539
Query: 306 LATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSE--GASPGSVLLTLTTVPQNTEFRESP 363
+T+ F YS V E G P ++L + + S
Sbjct: 540 TSTVSIVLLDINDFVPV-----FELSPYSVNVPENLGTLPRTILQVVAR--DDDRGSNSK 592
Query: 364 LQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSIS---NDTASINISV 420
L + + + + F ++ +GE+ + +SLD ET + + TDS S T +IN+ V
Sbjct: 593 LSYVLFGGNEDNAFTLSASGELGVTQSLDRETKERFVLMITATDSGSPALTGTGTINVIV 652
Query: 421 EDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGDAGTLA-LSLAGQHARM 479
+DVN+ P F Y A D DA A + + G +++
Sbjct: 653 DDVNDNVPTFASKAY------FTTIPEDAPTGTDVLLVNASDADASKNAVIRIIGGNSQ- 705
Query: 480 FYINASGDLFLREEAIGNLNSSSLHLVATAIDSGIP-PRQTSVPV 523
F IN S + + + LV D+G P P +S V
Sbjct: 706 FTINPSTGQIITSALLDRETKDNYTLVVVCSDAGSPEPLSSSTSV 750
Score = 112 bits (269), Expect = 6e-24
Identities = 109/437 (24%), Positives = 183/437 (41%), Gaps = 24/437 (5%)
Query: 13 EDTPIGSIIGTLSVNGDPSEDL-GDITLRLQEKGAAVGIVPGSKNLTLLRALDREEKIGP 71
E T IGS + + DP E G + ++ + I + + + L + G
Sbjct: 1181 ELTEIGSKVTQVFAT-DPDEGSNGQVFYFIKSQSEYFRINATTGEIFNKQILKYQNVTGF 1239
Query: 72 SNVYVNVRCDRRRTTD---PSFV--IPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXX 126
SNV +N ++D PS + V++ + D NDNAPQ+ + Y V++
Sbjct: 1240 SNVNINRHSFIVTSSDRGKPSLISETTVTINIVDSNDNAPQFLKSKYFTPVTKNVKVGTK 1299
Query: 127 XXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLR 186
D G +S + Y + H +N+ I V + + NF I +
Sbjct: 1300 LIRVTAIDDKDFGLNSEVEYFISNDNHLGKFKLDNDTGWISVASSLIS-DLNQNFFITVT 1358
Query: 187 VQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQ 246
+D+G+PPL S T+ +TV + + P+F+ H +A +P+ G+ + T +SA D+
Sbjct: 1359 AKDKGNPPLSSQATVHITVTEENYHTPEFSQSHMSATIPESHSIGSIVRT----VSARDR 1414
Query: 247 DLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYA 305
D +N ++YS S+G+ + + +N TG + K L EL + + A D
Sbjct: 1415 DAAMNGLIKYSISSGNEEGIFAINSSTGILTLAKALDYELCQKHEMTISAI-----DGGW 1469
Query: 306 LATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQ 365
+A F Y TV E A G+ ++ L + + + +
Sbjct: 1470 VARTGYCSVTVNVIDVNDNSPVFLSDDYFPTVLENAPSGTTVIHLNAT--DADSGTNAVI 1527
Query: 366 FYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVM---VTDSISNDTASINISVE 421
Y S D F I+ N G + + LD+ET +Y V V D A++NI ++
Sbjct: 1528 AYTVQSSDSDLFVIDPNTGVITTQGFLDFETKQSYHLTVKAFNVPDEERCSFATVNIQLK 1587
Query: 422 DVNEWEPRFRHPQYEFE 438
NE+ PRF Y FE
Sbjct: 1588 GTNEYVPRFVSKLYYFE 1604
Score = 101 bits (243), Expect = 9e-21
Identities = 101/444 (22%), Positives = 192/444 (43%), Gaps = 38/444 (8%)
Query: 8 SFFISEDTPIGSIIGTLSVNGDPSEDLGDITLR---LQEKGAAVGIVPGSKNLTLLRALD 64
S + E++P+G + ++ + ED+G + + + I P + ++ + R L+
Sbjct: 1076 SAHVPENSPLGYTVTRVTTS---DEDIGINAISRYSIMDASLPFTINPSTGDIVISRPLN 1132
Query: 65 REEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXX 124
RE+ + V T + V++ V D+NDNAP++ Y + E
Sbjct: 1133 REDT---DRYRIRVSAHDSGWTVST---DVTIFVTDINDNAPRFSRTSYYLDCPELTEIG 1186
Query: 125 XXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFT-- 182
+D D+ G + + Y + SEY N I K+ L ++ V F+
Sbjct: 1187 SKVTQVFATDPDE-GSNGQVFYFIKS--QSEYFRI-NATTGEIFNKQILKYQNVTGFSNV 1242
Query: 183 ------IKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTT 236
+ D+G P L S+TT+ + ++D++D P+F Y + + + GT L
Sbjct: 1243 NINRHSFIVTSSDRGKPSLISETTVTINIVDSNDNAPQFLKSKYFTPVTKNVKVGTKLIR 1302
Query: 237 SPGPISAADQDLGINAPLQYSSTGD-HKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKA 295
+ D+D G+N+ ++Y + D H ++ DTG ++ LI++L+ + I + A
Sbjct: 1303 VT---AIDDKDFGLNSEVEYFISNDNHLGKFKLDNDTGWISVASSLISDLNQNFFITVTA 1359
Query: 296 TQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQ 355
NP + AT+ +F+Q S T+ E S GS++ T++ +
Sbjct: 1360 KDKGNPPLSSQATVHITVTEENYHTP-----EFSQSHMSATIPESHSIGSIVRTVSARDR 1414
Query: 356 NTEFRESPLQFYVSDRSFLDKFAINNA-GEVILRRSLDYETTSNYFYQVMVTDS---ISN 411
+ +++ +S + FAIN++ G + L ++LDYE + + D
Sbjct: 1415 DAAM-NGLIKYSISSGNEEGIFAINSSTGILTLAKALDYELCQKHEMTISAIDGGWVART 1473
Query: 412 DTASINISVEDVNEWEPRFRHPQY 435
S+ ++V DVN+ P F Y
Sbjct: 1474 GYCSVTVNVIDVNDNSPVFLSDDY 1497
Score = 99.1 bits (236), Expect = 6e-20
Identities = 97/383 (25%), Positives = 161/383 (42%), Gaps = 21/383 (5%)
Query: 57 LTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVR 116
+T+ + LDRE+ ++ V+ R +T + VS+ + D+ND P +E +PY+V
Sbjct: 509 ITVAKPLDREKT---PTYHLTVQATDRGSTPRTDTSTVSIVLLDINDFVPVFELSPYSVN 565
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFE 176
V E + D G +S L Y + G +E F + V + LD E
Sbjct: 566 VPENLGTLPRTILQVVARDDDRGSNSKLSYVLFGG--NEDNAFTLSASGELGVTQSLDRE 623
Query: 177 TVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTT 236
T F + + D GSP L T+ V V D +D P F + Y +P+DA GT +
Sbjct: 624 TKERFVLMITATDSGSPALTGTGTINVIVDDVNDNVPTFASKAYFTTIPEDAPTGTDVLL 683
Query: 237 SPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKAT 296
++A+D D NA ++ G + Q +N TGQ+ + L E + T+V+ +
Sbjct: 684 ----VNASDADASKNAVIRI--IGGNSQ-FTINPSTGQIITSALLDRETKDNYTLVVVCS 736
Query: 297 QVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQN 356
+P+ + +T +F Y T + PGS + +T +
Sbjct: 737 DAGSPEPLSSST----SVLVTVTDVNDNPPRFQHHPYVTHIPSPTLPGSFVFAVTVTDAD 792
Query: 357 TEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSIS-NDTAS 415
S L + +S R+ +KF I+ I+ S + V V D S T S
Sbjct: 793 IG-PNSELHYSLSGRN-SEKFHIDPLRGAIMAAG-PLNGASEVTFSVHVKDGGSFPKTDS 849
Query: 416 INISVEDVNEWE-PRFRHPQYEF 437
++V VN+ + P+ R + F
Sbjct: 850 TTVTVRFVNKADFPKVRAKEQTF 872
Score = 88.6 bits (210), Expect = 9e-17
Identities = 84/374 (22%), Positives = 156/374 (41%), Gaps = 28/374 (7%)
Query: 161 NELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHY 220
++L + + +PLDFE + + + + +D G PP S L +TVLD +D P F + +
Sbjct: 913 DQLTGQVSISQPLDFEKIQKYVVWIEARDGGFPPFSSYEKLDITVLDVNDNAPIFKEDPF 972
Query: 221 TALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATK 279
+ + ++ LT +SA D+D G N L Y G+ + +N TG++ + +
Sbjct: 973 ISEILENLSPRKILT-----VSAMDKDSGPNGQLDYEIVNGNMENSFSINHATGEIRSVR 1027
Query: 280 QLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSE 339
L E + +K++ +P + + +F+Q +S V E
Sbjct: 1028 PLDREKVSHYVLTIKSSDKGSPSQSTSVKVMINILDENDNAP-----RFSQ-IFSAHVPE 1081
Query: 340 GASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSN 398
+ G + +TT ++ + ++ + D S F IN + G++++ R L+ E T
Sbjct: 1082 NSPLGYTVTRVTTSDEDIGI-NAISRYSIMDASL--PFTINPSTGDIVISRPLNREDTDR 1138
Query: 399 YFYQVMVTDSISNDTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXX 458
Y +V DS + + I V D+N+ PRF Y +
Sbjct: 1139 YRIRVSAHDSGWTVSTDVTIFVTDINDNAPRFSRTSYYLDCPELTEIGSKVTQVFATD-- 1196
Query: 459 VAHDGDAGTLALSLAGQHARMFYINA-SGDLFLRE-------EAIGNLNSSSLHLVATAI 510
+G G + + Q + F INA +G++F ++ N+N + + T+
Sbjct: 1197 -PDEGSNGQVFYFIKSQ-SEYFRINATTGEIFNKQILKYQNVTGFSNVNINRHSFIVTSS 1254
Query: 511 DSGIPPRQTSVPVT 524
D G P + VT
Sbjct: 1255 DRGKPSLISETTVT 1268
Score = 87.4 bits (207), Expect = 2e-16
Identities = 123/524 (23%), Positives = 206/524 (39%), Gaps = 40/524 (7%)
Query: 6 VESFFISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQE--KGAAVGIVPGSKNLTLLRAL 63
V SF I EDT GS++ + D S G+IT + E + + P + L R L
Sbjct: 143 VYSFDIPEDTIPGSLVAAILATDDDSGVNGEITYIVNEDDEDGIFFLNPITGVFNLTRLL 202
Query: 64 DREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXX 123
D E + + VR + I V + DVNDN P + Y+ + E
Sbjct: 203 DYEVQ---QYYILTVRAE--DGGGQFTTIRVYFNILDVNDNPPIFSLNSYSTSLMENLPV 257
Query: 124 XXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLG-FENELEPIIVVKKPLDFETVNNFT 182
+D D G +S L Y++ G + LG F + ++ V K LD E+ + +
Sbjct: 258 GSTVLVFNVTDADD-GINSQLTYSIASG---DSLGQFTVDKNGVLKVLKALDRESQSFYN 313
Query: 183 IKLRVQDQGSPPLYSDT-TLQVTV--LDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPG 239
+ ++V D P T T QV++ LD +D P F T + E T + T
Sbjct: 314 LVVQVHDLPQIPASRFTSTAQVSIILLDVNDNPPTFLSPKLTYI-----PENTPIDTVVF 368
Query: 240 PISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVD 299
A D D G N+ ++Y+ + G+V T +L E + T+ + AT
Sbjct: 369 KAQATDPDSGPNSYIEYTLLNPLGNKFSIGTIDGEVRLTGELDREEVSNYTLTVVATDKG 428
Query: 300 NPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEF 359
P + + F Q Y ++E G+ ++ + E
Sbjct: 429 QPSLSSSTEVVVMVLDINDNNPI-----FAQALYKVEINENTLTGTDIIQVFAA-DGDEG 482
Query: 360 RESPLQFYVSDRSFLDKFAINN-AGEVILRRSLDYETTSNYFYQVMVTDSIS---NDTAS 415
+++ + + + +F I++ G + + + LD E T Y V TD S DT++
Sbjct: 483 TNGQVRYGIVNGNTNQEFRIDSVTGAITVAKPLDREKTPTYHLTVQATDRGSTPRTDTST 542
Query: 416 INISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGDAGTLA----LS 471
++I + D+N++ P F Y VA D D G+ + +
Sbjct: 543 VSIVLLDINDFVPVFELSPYSVN-----VPENLGTLPRTILQVVARDDDRGSNSKLSYVL 597
Query: 472 LAGQHARMFYINASGDLFLREEAIGNLNSSSLHLVATAIDSGIP 515
G F ++ASG+L + +++ L+ TA DSG P
Sbjct: 598 FGGNEDNAFTLSASGELGV-TQSLDRETKERFVLMITATDSGSP 640
Score = 82.6 bits (195), Expect = 6e-15
Identities = 82/354 (23%), Positives = 147/354 (41%), Gaps = 25/354 (7%)
Query: 91 VIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLP 150
V V + + D+NDN P + + V E D D+ G ++ + Y ++
Sbjct: 21 VFIVEITLQDINDNPPVFPTDMLDLTVEENIGDGSKIMQLTAMDADE-GANALVTYTIIS 79
Query: 151 GPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADD 210
G + + E +I ++ LD E + +++ +R D SD + +TV D +D
Sbjct: 80 GADDSFR-IDPESGDLIATRR-LDRERRSKYSLLVRADDGLQS---SDMRINITVSDVND 134
Query: 211 QNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQY-SSTGDHKQLIVVN 269
PKF+ Y+ +P+D G+ + I A D D G+N + Y + D + +N
Sbjct: 135 HTPKFSRPVYSFDIPEDTIPGSLVAA----ILATDDDSGVNGEITYIVNEDDEDGIFFLN 190
Query: 270 KDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFT 329
TG T+ L E+ + ++A D ++ + F+
Sbjct: 191 PITGVFNLTRLLDYEVQQYYILTVRAE--DGGGQFTTIRVYFNILDVNDNPPI-----FS 243
Query: 330 QKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRR 389
YST++ E GS +L V + S L + ++ L +F ++ G + + +
Sbjct: 244 LNSYSTSLMENLPVGSTVLVF-NVTDADDGINSQLTYSIASGDSLGQFTVDKNGVLKVLK 302
Query: 390 SLDYETTSNYFYQVMVTD------SISNDTASINISVEDVNEWEPRFRHPQYEF 437
+LD E+ S Y V V D S TA ++I + DVN+ P F P+ +
Sbjct: 303 ALDRESQSFYNLVVQVHDLPQIPASRFTSTAQVSIILLDVNDNPPTFLSPKLTY 356
Score = 82.6 bits (195), Expect = 6e-15
Identities = 100/426 (23%), Positives = 178/426 (41%), Gaps = 23/426 (5%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKN---LTLLRALDREE 67
I E IGSI+ T+S + G I + G GI + + LTL +ALD E
Sbjct: 1396 IPESHSIGSIVRTVSARDRDAAMNGLIKYSISS-GNEEGIFAINSSTGILTLAKALDYE- 1453
Query: 68 KIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXX 127
+ + D + V+V V DVNDN+P + Y V E
Sbjct: 1454 -LCQKHEMTISAIDGGWVARTGYC-SVTVNVIDVNDNSPVFLSDDYFPTVLENAPSGTTV 1511
Query: 128 XXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRV 187
+D D G ++ + Y V ++ N +I + LDFET ++ + ++
Sbjct: 1512 IHLNATDADS-GTNAVIAYTVQSSDSDLFVIDPNT--GVITTQGFLDFETKQSYHLTVKA 1568
Query: 188 QDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQD 247
+ S T+ + + ++ P+F + Y + + A +GT + G + A+D+D
Sbjct: 1569 FNVPDEERCSFATVNIQLKGTNEYVPRFVSKLYYFEISEAAPKGTIV----GEVFASDRD 1624
Query: 248 LGINAPLQYSSTGD-HKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYAL 306
LG + + Y G+ K+ +NK TGQ+ + L E + V++ + A N
Sbjct: 1625 LGTDGEVHYLIFGNSRKKGFQINKKTGQIYVSGILDREKEERVSLKVLAK---NFGSIRG 1681
Query: 307 ATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQF 366
A + + FT YS +SEG G+ + ++ ++ S +
Sbjct: 1682 ADIDEVTVNVTVLDANDPPI-FTLNIYSVQISEGVPIGTHVTFVSAFDSDSIPSWSRFSY 1740
Query: 367 YVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTDS---ISNDTASINISVED 422
++ + F+IN G++ + LD ET Y V+ DS + +AS+ +++ED
Sbjct: 1741 FIGSGNENGAFSINPQTGQITVTAELDRETLPIYNLSVLAVDSGTPSATGSASLLVTLED 1800
Query: 423 VNEWEP 428
+N+ P
Sbjct: 1801 INDNGP 1806
Score = 81.8 bits (193), Expect = 1e-14
Identities = 68/278 (24%), Positives = 131/278 (47%), Gaps = 13/278 (4%)
Query: 7 ESFFISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDRE 66
++F E+ P+ S++ T++ + E + + G I + +++ + LD E
Sbjct: 870 QTFMFPENQPVSSLVTTITGSSLRGEPMS-YYIASGNLGNTFQIDQLTGQVSISQPLDFE 928
Query: 67 EKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXX 126
KI V++ R D S+ + + V DVNDNAP ++ P+ + E
Sbjct: 929 -KIQKYVVWIEAR-DGGFPPFSSYE-KLDITVLDVNDNAPIFKEDPFISEILEN-LSPRK 984
Query: 127 XXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLR 186
D+D GP+ L Y ++ G + I V +PLD E V+++ + ++
Sbjct: 985 ILTVSAMDKDS-GPNGQLDYEIVNGNMENSFSINHATGEIRSV-RPLDREKVSHYVLTIK 1042
Query: 187 VQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQ 246
D+GSP + + + +LD +D P+F+ + ++A +P+++ G +T ++ +D+
Sbjct: 1043 SSDKGSPSQSTSVKVMINILDENDNAPRFS-QIFSAHVPENSPLGYTVTR----VTTSDE 1097
Query: 247 DLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLIAE 284
D+GINA +YS D +N TG + ++ L E
Sbjct: 1098 DIGINAISRYSIM-DASLPFTINPSTGDIVISRPLNRE 1134
Score = 81.4 bits (192), Expect = 1e-14
Identities = 97/426 (22%), Positives = 179/426 (42%), Gaps = 30/426 (7%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIV-PGSKNLTLLRALDREEKI 69
+ E+ P G+ + L+ S I +Q + + ++ P + +T LD E K
Sbjct: 1501 VLENAPSGTTVIHLNATDADSGTNAVIAYTVQSSDSDLFVIDPNTGVITTQGFLDFETK- 1559
Query: 70 GPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXX 129
+ ++ V+ + V++++ N+ P++ Y +SE
Sbjct: 1560 --QSYHLTVKAFNVPDEERCSFATVNIQLKGTNEYVPRFVSKLYYFEISEAAPKGTIVGE 1617
Query: 130 XXXSDRDQPGPHSALHYAVLPGPHSEYLGFE-NELEPIIVVKKPLDFETVNNFTIKLRVQ 188
SDRD G +HY + +S GF+ N+ I V LD E ++K+ +
Sbjct: 1618 VFASDRDL-GTDGEVHYLIFG--NSRKKGFQINKKTGQIYVSGILDREKEERVSLKVLAK 1674
Query: 189 DQGS--PPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQ 246
+ GS + T+ VTVLDA+D P FT Y+ + + GT +T +SA D
Sbjct: 1675 NFGSIRGADIDEVTVNVTVLDANDP-PIFTLNIYSVQISEGVPIGTHVTF----VSAFDS 1729
Query: 247 DLGINAPLQYS---STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDR 303
D I + ++S +G+ +N TGQ+ T +L E P + + A P
Sbjct: 1730 D-SIPSWSRFSYFIGSGNENGAFSINPQTGQITVTAELDRETLPIYNLSVLAVDSGTPSA 1788
Query: 304 YALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESP 363
A+L L ++ + V E PG++++TL + + + P
Sbjct: 1789 TGSASLLVTLEDINDNGPM---LTVSEGE----VMENKRPGTLVMTLQSTDPDLPPNQGP 1841
Query: 364 LQFY-VSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDS---ISNDTASINIS 419
+Y +S F+++ AG + R +D E ++++ V+ DS + T +++I+
Sbjct: 1842 FTYYLLSTGPATSYFSLSTAGVLSTTREIDREQIADFYLSVVTKDSGVPQMSSTGTVHIT 1901
Query: 420 VEDVNE 425
V D N+
Sbjct: 1902 VIDQND 1907
Score = 76.2 bits (179), Expect = 5e-13
Identities = 75/359 (20%), Positives = 145/359 (40%), Gaps = 18/359 (5%)
Query: 73 NVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXX 132
N ++ V + S V + V + N + P++ + + + E+
Sbjct: 1352 NFFITVTAKDKGNPPLSSQATVHITVTEENYHTPEFSQSHMSATIPESHSIGSIVRTVSA 1411
Query: 133 SDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGS 192
DRD + + Y++ G + E + N I+ + K LD+E + + D G
Sbjct: 1412 RDRDA-AMNGLIKYSISSG-NEEGIFAINSSTGILTLAKALDYELCQKHEMTISAIDGGW 1469
Query: 193 PPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINA 252
++ V V+D +D +P F + Y + ++A GT + ++A D D G NA
Sbjct: 1470 VARTGYCSVTVNVIDVNDNSPVFLSDDYFPTVLENAPSGTTVIH----LNATDADSGTNA 1525
Query: 253 PLQYSSTGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXX 312
+ Y+ L V++ +TG + L E S + +KA V + +R + AT+
Sbjct: 1526 VIAYTVQSSDSDLFVIDPNTGVITTQGFLDFETKQSYHLTVKAFNVPDEERCSFATVNIQ 1585
Query: 313 XXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRS 372
+F K Y +SE A G+++ + ++ + + + + S
Sbjct: 1586 LKGTNEYVP-----RFVSKLYYFEISEAAPKGTIVGEVFASDRDLG-TDGEVHYLIFGNS 1639
Query: 373 FLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTD--SISN---DTASINISVEDVNE 425
F IN G++ + LD E +V+ + SI D ++N++V D N+
Sbjct: 1640 RKKGFQINKKTGQIYVSGILDREKEERVSLKVLAKNFGSIRGADIDEVTVNVTVLDAND 1698
Score = 55.2 bits (127), Expect = 1e-06
Identities = 35/112 (31%), Positives = 51/112 (45%), Gaps = 3/112 (2%)
Query: 328 FTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVI 386
F TV E GS ++ LT + + + + L Y D F I+ +G++I
Sbjct: 38 FPTDMLDLTVEENIGDGSKIMQLTAM--DADEGANALVTYTIISGADDSFRIDPESGDLI 95
Query: 387 LRRSLDYETTSNYFYQVMVTDSISNDTASINISVEDVNEWEPRFRHPQYEFE 438
R LD E S Y V D + + INI+V DVN+ P+F P Y F+
Sbjct: 96 ATRRLDRERRSKYSLLVRADDGLQSSDMRINITVSDVNDHTPKFSRPVYSFD 147
Score = 49.2 bits (112), Expect = 6e-05
Identities = 64/283 (22%), Positives = 113/283 (39%), Gaps = 19/283 (6%)
Query: 9 FFISEDTPIGSIIGTLSVNGDPSEDLGDITLRL----QEKGAAVGIVPGSKNLTLLRALD 64
F ISE P G+I+G + + G++ + ++KG + G ++ + +
Sbjct: 1603 FEISEAAPKGTIVGEVFASDRDLGTDGEVHYLIFGNSRKKGFQINKKTGQIYVSGILDRE 1662
Query: 65 REEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXX 124
+EE++ + N R D + V+V V D ND P + Y+V++SE
Sbjct: 1663 KEERVSLKVLAKNFGSIRGADIDE---VTVNVTVLDAND-PPIFTLNIYSVQISEGVPIG 1718
Query: 125 XXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIK 184
D D S Y + G + + I V + LD ET+ + +
Sbjct: 1719 THVTFVSAFDSDSIPSWSRFSYFIGSGNENGAFSINPQTGQITVTAE-LDRETLPIYNLS 1777
Query: 185 LRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAA 244
+ D G+P +L VT+ D +D P T + ++ GT + T + +
Sbjct: 1778 VLAVDSGTPSATGSASLLVTLEDINDNGPMLTVSEGEVM--ENKRPGTLVMT----LQST 1831
Query: 245 DQDLGIN-APLQY--SSTGDHKQLIVVNKDTGQVAATKQLIAE 284
D DL N P Y STG ++ G ++ T+++ E
Sbjct: 1832 DPDLPPNQGPFTYYLLSTGPATSYFSLS-TAGVLSTTREIDRE 1873
Score = 47.2 bits (107), Expect = 3e-04
Identities = 52/213 (24%), Positives = 87/213 (40%), Gaps = 14/213 (6%)
Query: 6 VESFFISEDTPIGSIIGTLSV---NGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRA 62
+ S ISE PIG+ + +S + PS + + A I P + +T+
Sbjct: 1706 IYSVQISEGVPIGTHVTFVSAFDSDSIPSWSRFSYFIGSGNENGAFSINPQTGQITVTAE 1765
Query: 63 LDREEKIGPSNVY-VNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETX 121
LDRE +Y ++V T + + V + D+NDN P + V E
Sbjct: 1766 LDRETL----PIYNLSVLAVDSGTPSATGSASLLVTLEDINDNGPMLTVSEG--EVMENK 1819
Query: 122 XXXXXXXXXXXSDRDQPGPHSALHYAVLP-GPHSEYLGFENELEPIIVVKKPLDFETVNN 180
+D D P Y +L GP + Y F ++ + +D E + +
Sbjct: 1820 RPGTLVMTLQSTDPDLPPNQGPFTYYLLSTGPATSY--FSLSTAGVLSTTREIDREQIAD 1877
Query: 181 FTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNP 213
F + + +D G P + S T+ +TV+D +D NP
Sbjct: 1878 FYLSVVTKDSGVPQMSSTGTVHITVIDQND-NP 1909
>AB075518-1|BAE45762.1| 656|Homo sapiens putative protein product
of Nbla00548 protein.
Length = 656
Score = 112 bits (269), Expect = 6e-24
Identities = 109/437 (24%), Positives = 183/437 (41%), Gaps = 24/437 (5%)
Query: 13 EDTPIGSIIGTLSVNGDPSEDL-GDITLRLQEKGAAVGIVPGSKNLTLLRALDREEKIGP 71
E T IGS + + DP E G + ++ + I + + + L + G
Sbjct: 175 ELTEIGSKVTQVFAT-DPDEGSNGQVFYFIKSQSEYFRINATTGEIFNKQILKYQNVTGF 233
Query: 72 SNVYVNVRCDRRRTTD---PSFV--IPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXX 126
SNV +N ++D PS + V++ + D NDNAPQ+ + Y V++
Sbjct: 234 SNVNINRHSFIVTSSDRGKPSLISETTVTINIVDSNDNAPQFLKSKYFTPVTKNVKVGTK 293
Query: 127 XXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLR 186
D G +S + Y + H +N+ I V + + NF I +
Sbjct: 294 LIRVTAIDDKDFGLNSEVEYFISNDNHLGKFKLDNDTGWISVASSLIS-DLNQNFFITVT 352
Query: 187 VQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQ 246
+D+G+PPL S T+ +TV + + P+F+ H +A +P+ G+ + T +SA D+
Sbjct: 353 AKDKGNPPLSSQATVHITVTEENYHTPEFSQSHMSATIPESHSIGSIVRT----VSARDR 408
Query: 247 DLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYA 305
D +N ++YS S+G+ + + +N TG + K L EL + + A D
Sbjct: 409 DAAMNGLIKYSISSGNEEGIFAINSSTGILTLAKALDYELCQKHEMTISAI-----DGGW 463
Query: 306 LATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQ 365
+A F Y TV E A G+ ++ L + + + +
Sbjct: 464 VARTGYCSVTVNVIDVNDNSPVFLSDDYFPTVLENAPSGTTVIHLNAT--DADSGTNAVI 521
Query: 366 FYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVM---VTDSISNDTASINISVE 421
Y S D F I+ N G + + LD+ET +Y V V D A++NI ++
Sbjct: 522 AYTVQSSDSDLFVIDPNTGVITTQGFLDFETKQSYHLTVKAFNVPDEERCSFATVNIQLK 581
Query: 422 DVNEWEPRFRHPQYEFE 438
NE+ PRF Y FE
Sbjct: 582 GTNEYVPRFVSKLYYFE 598
Score = 101 bits (243), Expect = 9e-21
Identities = 101/444 (22%), Positives = 192/444 (43%), Gaps = 38/444 (8%)
Query: 8 SFFISEDTPIGSIIGTLSVNGDPSEDLGDITLR---LQEKGAAVGIVPGSKNLTLLRALD 64
S + E++P+G + ++ + ED+G + + + I P + ++ + R L+
Sbjct: 70 SAHVPENSPLGYTVTRVTTS---DEDIGINAISRYSIMDASLPFTINPSTGDIVISRPLN 126
Query: 65 REEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXX 124
RE+ + V T + V++ V D+NDNAP++ Y + E
Sbjct: 127 REDT---DRYRIRVSAHDSGWTVST---DVTIFVTDINDNAPRFSRTSYYLDCPELTEIG 180
Query: 125 XXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFT-- 182
+D D+ G + + Y + SEY N I K+ L ++ V F+
Sbjct: 181 SKVTQVFATDPDE-GSNGQVFYFIKS--QSEYFRI-NATTGEIFNKQILKYQNVTGFSNV 236
Query: 183 ------IKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTT 236
+ D+G P L S+TT+ + ++D++D P+F Y + + + GT L
Sbjct: 237 NINRHSFIVTSSDRGKPSLISETTVTINIVDSNDNAPQFLKSKYFTPVTKNVKVGTKLIR 296
Query: 237 SPGPISAADQDLGINAPLQYSSTGD-HKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKA 295
+ D+D G+N+ ++Y + D H ++ DTG ++ LI++L+ + I + A
Sbjct: 297 VT---AIDDKDFGLNSEVEYFISNDNHLGKFKLDNDTGWISVASSLISDLNQNFFITVTA 353
Query: 296 TQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQ 355
NP + AT+ +F+Q S T+ E S GS++ T++ +
Sbjct: 354 KDKGNPPLSSQATVHITVTEENYHTP-----EFSQSHMSATIPESHSIGSIVRTVSARDR 408
Query: 356 NTEFRESPLQFYVSDRSFLDKFAINNA-GEVILRRSLDYETTSNYFYQVMVTDS---ISN 411
+ +++ +S + FAIN++ G + L ++LDYE + + D
Sbjct: 409 DAAM-NGLIKYSISSGNEEGIFAINSSTGILTLAKALDYELCQKHEMTISAIDGGWVART 467
Query: 412 DTASINISVEDVNEWEPRFRHPQY 435
S+ ++V DVN+ P F Y
Sbjct: 468 GYCSVTVNVIDVNDNSPVFLSDDY 491
Score = 89.4 bits (212), Expect = 5e-17
Identities = 106/475 (22%), Positives = 193/475 (40%), Gaps = 31/475 (6%)
Query: 60 LRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSE 119
+R LDRE+ S+ + ++ + + S + V + + D NDNAP++ ++ V E
Sbjct: 20 VRPLDREKV---SHYVLTIKSSDKGSPSQSTSVKVMINILDENDNAPRFSQI-FSAHVPE 75
Query: 120 TXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFE-NELEPIIVVKKPLDFETV 178
SD D G ++ Y+++ L F N IV+ +PL+ E
Sbjct: 76 NSPLGYTVTRVTTSDED-IGINAISRYSIMDAS----LPFTINPSTGDIVISRPLNREDT 130
Query: 179 NNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSP 238
+ + I++ D G + +D T+ VT D +D P+F+ Y P+ E G+ +T
Sbjct: 131 DRYRIRVSAHDSGW-TVSTDVTIFVT--DINDNAPRFSRTSYYLDCPELTEIGSKVT--- 184
Query: 239 GPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLIAELD----PSVTIVLK 294
+ A D D G N + Y + +N TG++ KQ++ + +V I
Sbjct: 185 -QVFATDPDEGSNGQVFY-FIKSQSEYFRINATTGEI-FNKQILKYQNVTGFSNVNINRH 241
Query: 295 ATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVP 354
+ V + DR + + QF + +Y T V++ G+ L+ +T +
Sbjct: 242 SFIVTSSDRGKPSLISETTVTINIVDSNDNAPQFLKSKYFTPVTKNVKVGTKLIRVTAID 301
Query: 355 QNTEFRESPLQFYVSDRSFLDKFAI-NNAGEVILRRSLDYETTSNYFYQVMVTDSISNDT 413
S +++++S+ + L KF + N+ G + + SL + N+F V D N
Sbjct: 302 DKDFGLNSEVEYFISNDNHLGKFKLDNDTGWISVASSLISDLNQNFFITVTAKDK-GNPP 360
Query: 414 ASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGDA---GTLAL 470
S +V + E + P++ + A D DA G +
Sbjct: 361 LSSQATVH-ITVTEENYHTPEFS-QSHMSATIPESHSIGSIVRTVSARDRDAAMNGLIKY 418
Query: 471 SL-AGQHARMFYINASGDLFLREEAIGNLNSSSLHLVATAIDSGIPPRQTSVPVT 524
S+ +G +F IN+S + +A+ + +AID G R VT
Sbjct: 419 SISSGNEEGIFAINSSTGILTLAKALDYELCQKHEMTISAIDGGWVARTGYCSVT 473
Score = 70.1 bits (164), Expect = 3e-11
Identities = 59/275 (21%), Positives = 111/275 (40%), Gaps = 11/275 (4%)
Query: 73 NVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXX 132
N ++ V + S V + V + N + P++ + + + E+
Sbjct: 346 NFFITVTAKDKGNPPLSSQATVHITVTEENYHTPEFSQSHMSATIPESHSIGSIVRTVSA 405
Query: 133 SDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGS 192
DRD + + Y++ G + E + N I+ + K LD+E + + D G
Sbjct: 406 RDRDA-AMNGLIKYSISSG-NEEGIFAINSSTGILTLAKALDYELCQKHEMTISAIDGGW 463
Query: 193 PPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINA 252
++ V V+D +D +P F + Y + ++A GT + ++A D D G NA
Sbjct: 464 VARTGYCSVTVNVIDVNDNSPVFLSDDYFPTVLENAPSGTTVIH----LNATDADSGTNA 519
Query: 253 PLQYSSTGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXX 312
+ Y+ L V++ +TG + L E S + +KA V + +R + AT+
Sbjct: 520 VIAYTVQSSDSDLFVIDPNTGVITTQGFLDFETKQSYHLTVKAFNVPDEERCSFATVNIQ 579
Query: 313 XXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVL 347
+F K Y +SE A G+++
Sbjct: 580 LKGTNEYVP-----RFVSKLYYFEISEAAPKGTIV 609
Score = 60.5 bits (140), Expect = 3e-08
Identities = 67/269 (24%), Positives = 114/269 (42%), Gaps = 15/269 (5%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKN---LTLLRALDREE 67
I E IGSI+ T+S + G I + G GI + + LTL +ALD E
Sbjct: 390 IPESHSIGSIVRTVSARDRDAAMNGLIKYSISS-GNEEGIFAINSSTGILTLAKALDYE- 447
Query: 68 KIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXX 127
+ + D + V+V V DVNDN+P + Y V E
Sbjct: 448 -LCQKHEMTISAIDGGWVARTGYC-SVTVNVIDVNDNSPVFLSDDYFPTVLENAPSGTTV 505
Query: 128 XXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRV 187
+D D G ++ + Y V ++ N +I + LDFET ++ + ++
Sbjct: 506 IHLNATDADS-GTNAVIAYTVQSSDSDLFVIDPNT--GVITTQGFLDFETKQSYHLTVKA 562
Query: 188 QDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQD 247
+ S T+ + + ++ P+F + Y + + A +GT + G + A+D+D
Sbjct: 563 FNVPDEERCSFATVNIQLKGTNEYVPRFVSKLYYFEISEAAPKGTIV----GEVFASDRD 618
Query: 248 LGINAPLQYSSTGD-HKQLIVVNKDTGQV 275
LG + + Y G+ K+ +NK TGQ+
Sbjct: 619 LGTDGEVHYLIFGNSRKKGFQINKKTGQI 647
Score = 43.2 bits (97), Expect = 0.004
Identities = 55/274 (20%), Positives = 106/274 (38%), Gaps = 22/274 (8%)
Query: 260 GDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXX 319
G+ + +N TG++ + + L E + +K++ +P + +
Sbjct: 2 GNMENSFSINHATGEIRSVRPLDREKVSHYVLTIKSSDKGSPSQSTSVKVMINILDENDN 61
Query: 320 XXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAI 379
+F+Q +S V E + G + +TT ++ ++ + D S F I
Sbjct: 62 AP-----RFSQI-FSAHVPENSPLGYTVTRVTTSDEDIGINAIS-RYSIMDASL--PFTI 112
Query: 380 N-NAGEVILRRSLDYETTSNYFYQVMVTDSISNDTASINISVEDVNEWEPRFRHPQYEFE 438
N + G++++ R L+ E T Y +V DS + + I V D+N+ PRF Y +
Sbjct: 113 NPSTGDIVISRPLNREDTDRYRIRVSAHDSGWTVSTDVTIFVTDINDNAPRFSRTSYYLD 172
Query: 439 XXXXXXXXXXXXXXXXXXXXVAHDGDAGTLALSLAGQHARMFYINA-SGDLFLRE----- 492
+G G + + Q + F INA +G++F ++
Sbjct: 173 CPELTEIGSKVTQVFATD---PDEGSNGQVFYFIKSQ-SEYFRINATTGEIFNKQILKYQ 228
Query: 493 --EAIGNLNSSSLHLVATAIDSGIPPRQTSVPVT 524
N+N + + T+ D G P + VT
Sbjct: 229 NVTGFSNVNINRHSFIVTSSDRGKPSLISETTVT 262
>BC113416-1|AAI13417.1| 799|Homo sapiens cadherin 8, type 2
protein.
Length = 799
Score = 111 bits (268), Expect = 8e-24
Identities = 112/432 (25%), Positives = 179/432 (41%), Gaps = 26/432 (6%)
Query: 20 IIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEKIGPSNVYVNVR 79
++G L + DP L G I + ++ ++ LDREEK + V
Sbjct: 81 LVGRLHTDLDPGSKKIKYILSGDGAGTIFQINDVTGDIHAIKRLDREEKAEYTLTAQAVD 140
Query: 80 CDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQP- 138
+ + +P + V+ D+NDNAP++ PY V E +D D P
Sbjct: 141 WETSKPLEPPSEFIIKVQ--DINDNAPEFLNGPYHATVPEMSILGTSVTNVTATDADDPV 198
Query: 139 -GPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQG--SPPL 195
G + L Y++L G Y E E I +D E + + ++ +D G S L
Sbjct: 199 YGNSAKLVYSILEG--QPYFSIEPETAIIKTALPNMDREAKEEYLVVIQAKDMGGHSGGL 256
Query: 196 YSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQ 255
TTL VT+ D +D PKF Y +P+D GT + G + A DQD+G NA
Sbjct: 257 SGTTTLTVTLTDVNDNPPKFAQSLYHFSVPEDVVLGTAI----GRVKANDQDIGENAQSS 312
Query: 256 YS-STGDHKQLIVVNKDT----GQVAATKQLIAELDPSVTIVLKATQVDNPDRYA-LATL 309
Y GD L + D G + K L E S T+ ++A V R++
Sbjct: 313 YDIIDGDGTALFEITSDAQAQDGIIRLRKPLDFETKKSYTLKVEAANVHIDPRFSGRGPF 372
Query: 310 XXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVS 369
F+ Y V E A+ SV+ +T ++ + SP++F +
Sbjct: 373 KDTATVKIVVEDADEPPVFSSPTYLLEVHENAALNSVIGQVTA--RDPDITSSPIRFSID 430
Query: 370 DRSFLDK-FAIN-NAGEVILRRSLDYETTSNYFYQVMVTDSISNDTAS---INISVEDVN 424
+ L++ F IN + G++ L LD E + + ++ T+ ++ S + I V DVN
Sbjct: 431 RHTDLERQFNINADDGKITLATPLDRELSVWHNITIIATEIRNHSQISRVPVAIKVLDVN 490
Query: 425 EWEPRFRHPQYE 436
+ P F +YE
Sbjct: 491 DNAPEFA-SEYE 501
Score = 50.8 bits (116), Expect = 2e-05
Identities = 49/202 (24%), Positives = 87/202 (43%), Gaps = 12/202 (5%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQ---EKGAAVGIVPGSKNLTLLRALDREE 67
+ E+ + S+IG ++ DP I + + I +TL LDRE
Sbjct: 400 VHENAALNSVIGQVTAR-DPDITSSPIRFSIDRHTDLERQFNINADDGKITLATPLDREL 458
Query: 68 KIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXX 127
+ N+ + + + R + S V PV+++V DVNDNAP++ + Y + E
Sbjct: 459 SVW-HNITI-IATEIRNHSQISRV-PVAIKVLDVNDNAPEF-ASEYEAFLCENGKPGQVI 514
Query: 128 XXXXXSDRDQPGPHSALHYAVLPGP--HSEYLGFENELEPIIVVKKPLDFETVNN--FTI 183
D+D P Y++LP + + +NE + ++ K F + +
Sbjct: 515 QTVSAMDKDDPKNGHYFLYSLLPEMVNNPNFTIKKNEDNSLSILAKHNGFNRQKQEVYLL 574
Query: 184 KLRVQDQGSPPLYSDTTLQVTV 205
+ + D G+PPL S +TL + V
Sbjct: 575 PIIISDSGNPPLSSTSTLTIRV 596
>AB035305-1|BAA87419.1| 799|Homo sapiens cadherin-8 protein.
Length = 799
Score = 111 bits (268), Expect = 8e-24
Identities = 112/432 (25%), Positives = 179/432 (41%), Gaps = 26/432 (6%)
Query: 20 IIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEKIGPSNVYVNVR 79
++G L + DP L G I + ++ ++ LDREEK + V
Sbjct: 81 LVGRLHTDLDPGSKKIKYILSGDGAGTIFQINDVTGDIHAIKRLDREEKAEYTLTAQAVD 140
Query: 80 CDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQP- 138
+ + +P + V+ D+NDNAP++ PY V E +D D P
Sbjct: 141 WETSKPLEPPSEFIIKVQ--DINDNAPEFLNGPYHATVPEMSILGTSVTNVTATDADDPV 198
Query: 139 -GPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQG--SPPL 195
G + L Y++L G Y E E I +D E + + ++ +D G S L
Sbjct: 199 YGNSAKLVYSILEG--QPYFSIEPETAIIKTALPNMDREAKEEYLVVIQAKDMGGHSGGL 256
Query: 196 YSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQ 255
TTL VT+ D +D PKF Y +P+D GT + G + A DQD+G NA
Sbjct: 257 SGTTTLTVTLTDVNDNPPKFAQSLYHFSVPEDVVLGTAI----GRVKANDQDIGENAQSS 312
Query: 256 YS-STGDHKQLIVVNKDT----GQVAATKQLIAELDPSVTIVLKATQVDNPDRYA-LATL 309
Y GD L + D G + K L E S T+ ++A V R++
Sbjct: 313 YDIIDGDGTALFEITSDAQAQDGIIRLRKPLDFETKKSYTLKVEAANVHIDPRFSGRGPF 372
Query: 310 XXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVS 369
F+ Y V E A+ SV+ +T ++ + SP++F +
Sbjct: 373 KDTATVKIVVEDADEPPVFSSPTYLLEVHENAALNSVIGQVTA--RDPDITSSPIRFSID 430
Query: 370 DRSFLDK-FAIN-NAGEVILRRSLDYETTSNYFYQVMVTDSISNDTAS---INISVEDVN 424
+ L++ F IN + G++ L LD E + + ++ T+ ++ S + I V DVN
Sbjct: 431 RHTDLERQFNINADDGKITLATPLDRELSVWHNITIIATEIRNHSQISRVPVAIKVLDVN 490
Query: 425 EWEPRFRHPQYE 436
+ P F +YE
Sbjct: 491 DNAPEFA-SEYE 501
Score = 50.8 bits (116), Expect = 2e-05
Identities = 49/202 (24%), Positives = 87/202 (43%), Gaps = 12/202 (5%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQ---EKGAAVGIVPGSKNLTLLRALDREE 67
+ E+ + S+IG ++ DP I + + I +TL LDRE
Sbjct: 400 VHENAALNSVIGQVTAR-DPDITSSPIRFSIDRHTDLERQFNINADDGKITLATPLDREL 458
Query: 68 KIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXX 127
+ N+ + + + R + S V PV+++V DVNDNAP++ + Y + E
Sbjct: 459 SVW-HNITI-IATEIRNHSQISRV-PVAIKVLDVNDNAPEF-ASEYEAFLCENGKPGQVI 514
Query: 128 XXXXXSDRDQPGPHSALHYAVLPGP--HSEYLGFENELEPIIVVKKPLDFETVNN--FTI 183
D+D P Y++LP + + +NE + ++ K F + +
Sbjct: 515 QTVSAMDKDDPKNGHYFLYSLLPEMVNNPNFTIKKNEDNSLSILAKHNGFNRQKQEVYLL 574
Query: 184 KLRVQDQGSPPLYSDTTLQVTV 205
+ + D G+PPL S +TL + V
Sbjct: 575 PIIISDSGNPPLSSTSTLTIRV 596
>L34060-1|AAA35628.1| 793|Homo sapiens cadherin-8 protein.
Length = 793
Score = 109 bits (263), Expect = 3e-23
Identities = 112/432 (25%), Positives = 178/432 (41%), Gaps = 26/432 (6%)
Query: 20 IIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEKIGPSNVYVNVR 79
++G L + DP L G I + ++ ++ LDREEK + V
Sbjct: 74 LVGRLHTDLDPGSKKIKYILSGDGAGTIFQINDVTGDIHAIKRLDREEKAEYTLTAQAVD 133
Query: 80 CDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQP- 138
+ + +P + V+ D+NDNAP++ PY V E +D D P
Sbjct: 134 WETSKPLEPPSEFIIKVQ--DINDNAPEFLNGPYHATVPEMSILGTSVTNVTATDADDPV 191
Query: 139 -GPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQG--SPPL 195
G + L Y++L G Y E E I +D E + + ++ +D G S L
Sbjct: 192 YGNSAKLVYSILEG--QPYFSIEPETAIIKTALPNMDREAKEEYLVVIQAKDMGGHSGGL 249
Query: 196 YSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQ 255
TTL VT+ D +D PKF Y +P+D GT + G + A DQD+G NA
Sbjct: 250 SGTTTLTVTLTDVNDNPPKFAQSLYHFSVPEDVVLGTAI----GRVKANDQDIGENAQSS 305
Query: 256 YS-STGDHKQLIVVNKDT----GQVAATKQLIAELDPSVTIVLKATQVDNPDRYA-LATL 309
Y GD L + D G + K L E S T+ +A V R++
Sbjct: 306 YDIIDGDGTALFEITSDAQAQDGIIRLRKPLDFETKKSYTLKDEAANVHIDPRFSGRGPF 365
Query: 310 XXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVS 369
F+ Y V E A+ SV+ +T ++ + SP++F +
Sbjct: 366 KDTATVKIVVEDADEPPVFSSPTYLLEVHENAALNSVIGQVTA--RDPDITSSPIRFSID 423
Query: 370 DRSFLDK-FAIN-NAGEVILRRSLDYETTSNYFYQVMVTDSISNDTAS---INISVEDVN 424
+ L++ F IN + G++ L LD E + + ++ T+ ++ S + I V DVN
Sbjct: 424 RHTDLERQFNINADDGKITLATPLDRELSVWHNITIIATEIRNHSQISRVPVAIKVLDVN 483
Query: 425 EWEPRFRHPQYE 436
+ P F +YE
Sbjct: 484 DNAPEFA-SEYE 494
Score = 50.8 bits (116), Expect = 2e-05
Identities = 49/202 (24%), Positives = 87/202 (43%), Gaps = 12/202 (5%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQ---EKGAAVGIVPGSKNLTLLRALDREE 67
+ E+ + S+IG ++ DP I + + I +TL LDRE
Sbjct: 393 VHENAALNSVIGQVTAR-DPDITSSPIRFSIDRHTDLERQFNINADDGKITLATPLDREL 451
Query: 68 KIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXX 127
+ N+ + + + R + S V PV+++V DVNDNAP++ + Y + E
Sbjct: 452 SVW-HNITI-IATEIRNHSQISRV-PVAIKVLDVNDNAPEF-ASEYEAFLCENGKPGQVI 507
Query: 128 XXXXXSDRDQPGPHSALHYAVLPGP--HSEYLGFENELEPIIVVKKPLDFETVNN--FTI 183
D+D P Y++LP + + +NE + ++ K F + +
Sbjct: 508 QTVSAMDKDDPKNGHYFLYSLLPEMVNNPNFTIKKNEDNSLSILAKHNGFNRQKQEVYLL 567
Query: 184 KLRVQDQGSPPLYSDTTLQVTV 205
+ + D G+PPL S +TL + V
Sbjct: 568 PIIISDSGNPPLSSTSTLTIRV 589
>AB053446-1|BAB61903.2| 3434|Homo sapiens KIAA1773 protein protein.
Length = 3434
Score = 108 bits (259), Expect = 1e-22
Identities = 122/504 (24%), Positives = 202/504 (40%), Gaps = 38/504 (7%)
Query: 13 EDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEKIGPS 72
E TP GS I ++S S G I+ L + P + L + G
Sbjct: 2523 EHTPPGSAILSVSATDRDSGANGHISYHLASPADGFSVDPNNGTLFTIVGTVALGHDGSG 2582
Query: 73 NVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXX 132
V V + + V V++ D ND+AP + + Y V V+E
Sbjct: 2583 AVDVVLEARDHGAPGRAARATVHVQLQDQNDHAPSFTLSHYRVAVTEDLPPGSTLLTLEA 2642
Query: 133 SDRDQPGPHSALHYAVLPGPHSEYLGFENELEPI-------------IVVKKPLDFETVN 179
+D D H+A+ Y+++ G E L +V+ +PLDFE++
Sbjct: 2643 TDADGSRSHAAVDYSIISGNWGRVFQLEPRLAEAGESAGPGPRALGCLVLLEPLDFESLT 2702
Query: 180 NFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPG 239
+ + + D+G PP S + VTVLD +D P FT Y +P+D G L
Sbjct: 2703 QYNLTVAAADRGQPPQSSVVPVTVTVLDVNDNPPVFTRASYRVTVPEDTPVGAELL---- 2758
Query: 240 PISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQV 298
+ A+D D G + ++++ S+GD L +++ +G + L E +V++A
Sbjct: 2759 HVEASDADPGPHGLVRFTVSSGDPSGLFELDESSGTLRLAHALDCETQARHQLVVQAADP 2818
Query: 299 DNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNT- 357
+ALA + F ST+V+E PG+++ TL + +
Sbjct: 2819 AGA-HFALAPVTIEVQDVNDHGPA-----FPLNLLSTSVAENQPPGTLVTTLHAIDGDAG 2872
Query: 358 ---EFRESPLQFYVSDRSFLDKFAINNA-GEVILRRSLDYETTSNYFYQVMVTDSISNDT 413
R S L+ + FA+N++ GE+ R DYE T ++ V D+ N +
Sbjct: 2873 AFGRLRYSLLEAGPGPEG-REAFALNSSTGELRARVPFDYEHTESFRLLVGAADA-GNLS 2930
Query: 414 ASINIS--VEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGDAGTLALS 471
AS+ +S V +E++P F P + F+ DG A L L
Sbjct: 2931 ASVTVSVLVTGEDEYDPVFLAPAFHFQVPEGARRGHSLGHVQATD----EDGGADGLVLY 2986
Query: 472 LAGQHARMFYIN-ASGDLFLREEA 494
+ F IN +G L+LR ++
Sbjct: 2987 SLATSSPYFGINQTTGALYLRVDS 3010
Score = 92.7 bits (220), Expect = 5e-18
Identities = 128/535 (23%), Positives = 201/535 (37%), Gaps = 41/535 (7%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQ-EKGAAVG----IVPGSKNLTLLRALDR 65
I E+ P G++IG +S G P+ + + ++G+ VG I S + R LDR
Sbjct: 187 IDEEQPAGTLIGDISA-GLPAGTAAPLMYFISAQEGSGVGTDLAIDEHSGVVRTARVLDR 245
Query: 66 EEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXX 125
E++ R T + V+VRV D+ND+AP + A A++V E
Sbjct: 246 EQRD---------RYRFTAVTPDGATVEVTVRVADINDHAPAFPQARAALQVPEHTAFGT 296
Query: 126 XXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPI------IVVKKPLDFETVN 179
D D G YA+ E E P +VV LD E +
Sbjct: 297 RYPLEPARDADA-GRLGTQGYALSGDGAGETFRLETRPGPDGTPVPELVVTGELDRENRS 355
Query: 180 NFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPG 239
++ ++L D GSPP + L VT+LD +D P F Y A++ + G+ +
Sbjct: 356 HYMLQLEAYDGGSPPRRAQALLDVTLLDINDHAPAFNQSRYHAVVSESLAPGSPVL---- 411
Query: 240 PISAADQDLGINAPLQY-----SSTGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLK 294
+ A+D D G+N + Y S GD ++ TG + + L E +V++
Sbjct: 412 QVFASDADAGVNGAVTYEINRRQSEGDGP--FSIDAHTGLLQLERPLDFEQRRVHELVVQ 469
Query: 295 ATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLT-TV 353
A A + + F S VSE A PG ++ ++ +
Sbjct: 470 ARDGGAHPELGSAFVTVHVRDANDNQPSMTVI-FLSADGSPQVSEAAPPGQLVARISVSD 528
Query: 354 PQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSIS--- 410
P + +F + + F + V + R LD E Y +V TDS S
Sbjct: 529 PDDGDFAHVNVSLEGGEGHFALSTQDSVIYLVCVARRLDREERDAYNLRVTATDSGSPPL 588
Query: 411 NDTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGDAGTLAL 470
A+ + V DVN+ P F Y E G G +
Sbjct: 589 RAEAAFVLHVTDVNDNAPAFDRQLYRPEPLPEVALPGSFVVRVTARD--PDQGTNGQVTY 646
Query: 471 SLA-GQHARMFYINASGDLFLREEAIGNLNSSSLHLVATAIDSGIPPRQTSVPVT 524
SLA G H F I+ + + ++ L+ A D G+PP +S V+
Sbjct: 647 SLAPGAHTHWFSIDPTSGIITTAASLDYELEPQPQLIVVATDGGLPPLASSATVS 701
Score = 89.4 bits (212), Expect = 5e-17
Identities = 121/505 (23%), Positives = 187/505 (37%), Gaps = 35/505 (6%)
Query: 30 PSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEKIGPSNVYVNVRCDRRRTTDPS 89
P+ D+ LR + A+ + + L+ R LDRE P+ + + DR
Sbjct: 1604 PNSDVRYRLLRQEPPVPALRLDARTGALSAPRGLDRETT--PALLLLVEATDRPANASRR 1661
Query: 90 FVIPVSVRVW--DVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYA 147
VS RV+ D NDNAP + +P VR+ E D D G + + Y
Sbjct: 1662 RAARVSARVFVTDENDNAPVF-ASPSRVRLPEDQPPGPAALHVVARDPDL-GEAARVSYR 1719
Query: 148 VLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLD 207
+ G + + + VV+ PLD E + + D GSPP + L V+V D
Sbjct: 1720 LASGGDGHFR-LHSSTGALSVVR-PLDREQRAEHVLTVVASDHGSPPRSATQVLTVSVAD 1777
Query: 208 ADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIV 267
+D+ P F + Y+ LL ++ GT L T + A D D+G N + Y G +
Sbjct: 1778 VNDEAPTFQQQEYSVLLRENNPPGTSLLT----LRATDPDVGANGQVTYG--GVSSESFS 1831
Query: 268 VNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQ 327
++ DTG + + L E + + + A +P + T+
Sbjct: 1832 LDPDTGVLTTLRALDREEQEEINLTVYAQDRGSPPQLTHVTVRVAVEDENDHAPT----- 1886
Query: 328 FTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAINNA-GEVI 386
F S V EG P + LT+ LQ+ + D F ++ A GE
Sbjct: 1887 FGSAHLSLEVPEGQDPQT--LTMLRASDPDVGANGQLQYRILDGDPSGAFVLDLASGEFG 1944
Query: 387 LRRSLDYETTSNYFYQVMVTDS---ISNDTASINISVEDVNEWEPRFRHPQYEFEXXXXX 443
R LD E + ++ D + T + ++V D N+ P F P Y E
Sbjct: 1945 TMRPLDREVEPAFQLRIEARDGGQPALSATLLLTVTVLDANDHAPAFPVPAYSVEVPEDV 2004
Query: 444 XXXXXXXXXXXXXXXVAHDGDAGT---LALSLAGQHARMFYINASGDLFLREEAIGNLNS 500
AHD DAG + L A F + S A+
Sbjct: 2005 PAGTLLLQLQ------AHDPDAGANGHVTYYLGAGTAGAFLLEPSSGELRTAAALDREQC 2058
Query: 501 SSLHLVATAID-SGIPPRQTSVPVT 524
S +A+D + P T+V VT
Sbjct: 2059 PSYTFSVSAVDGAAAGPLSTTVSVT 2083
Score = 88.2 bits (209), Expect = 1e-16
Identities = 109/437 (24%), Positives = 170/437 (38%), Gaps = 28/437 (6%)
Query: 14 DTPIGSIIGT--LSVNGDPSEDLGDITLRLQEKGAA--VGIVPGSKNLTLLRALDREEKI 69
D P G+ GT L V + D G IT L +GA+ G+ P S L + ALDRE +
Sbjct: 1144 DLPSGTTAGTQVLQVQAQ-APDGGPITYHLAAEGASSPFGLEPQSGWLWVRAALDREAQE 1202
Query: 70 GPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXX 129
+ V + + V V + + N+++P+ P + V+E
Sbjct: 1203 LYILKVMAVSGSKAELGQQTGTATVRVSILNQNEHSPRLSEDPTFLAVAENQPPGTSVGR 1262
Query: 130 XXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQD 189
+DRD GP+ L Y++ + + + LD E +++ + ++VQD
Sbjct: 1263 VFATDRDS-GPNGRLTYSLQQLSEDSKAFRIHPQTGEVTTLQTLDREQQSSYQLLVQVQD 1321
Query: 190 QGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTA------LLPDDAEEGTFLTTSPGPISA 243
GSPP + T+ V VLD +D +P F A +PD GT +TT + A
Sbjct: 1322 GGSPPRSTTGTVHVAVLDLNDNSPTFLQASGAAGGGLPIQVPDRVPPGTLVTT----LQA 1377
Query: 244 ADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDR 303
D D G N + Y+ TG +L ++ +G++ LI P + L A +P R
Sbjct: 1378 KDPDEGENGTILYTLTGPGSELFSLHPHSGELLTAAPLIRAERPHYVLTLSAHDQGSPPR 1437
Query: 304 YALATLXXXXXXXXXXXXXXXXLQFTQKQ------YSTTVSEGASPGSVLLTLTTVPQNT 357
A L L + T +EG PGS LL P+
Sbjct: 1438 SASLQLLVQVLPSARLAEPPPDLAERDPAAPVPVVLTVTAAEGLRPGS-LLGSVAAPEPA 1496
Query: 358 EFRESPLQFYVSDRSFLDKFAINNA-GEVILRRSLDYETTSNYFYQVMVTDSISNDTA-- 414
V FA++ A G + L R LD+E + + + A
Sbjct: 1497 GVGALTYTL-VGGADPEGTFALDAASGRLYLARPLDFEAGPPWRALTVRAEGPGGAGARL 1555
Query: 415 -SINISVEDVNEWEPRF 430
+ + V+D NE P F
Sbjct: 1556 LRVQVQVQDENEHAPAF 1572
Score = 87.0 bits (206), Expect = 3e-16
Identities = 79/288 (27%), Positives = 118/288 (40%), Gaps = 11/288 (3%)
Query: 8 SFFISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREE 67
S + E+ P G+ + TL G +T + + P + LT LRALDREE
Sbjct: 1791 SVLLRENNPPGTSLLTLRATDPDVGANGQVTYG-GVSSESFSLDPDTGVLTTLRALDREE 1849
Query: 68 KIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXX 127
+ + + V R + + V V V D ND+AP + A ++ V E
Sbjct: 1850 Q---EEINLTVYAQDRGSPPQLTHVTVRVAVEDENDHAPTFGSAHLSLEVPE-GQDPQTL 1905
Query: 128 XXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRV 187
SD D G + L Y +L G S + ++ PLD E F +++
Sbjct: 1906 TMLRASDPDV-GANGQLQYRILDGDPSGAFVLDLASGEFGTMR-PLDREVEPAFQLRIEA 1963
Query: 188 QDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQD 247
+D G P L + L VTVLDA+D P F Y+ +P+D GT L + A D D
Sbjct: 1964 RDGGQPALSATLLLTVTVLDANDHAPAFPVPAYSVEVPEDVPAGTLLL----QLQAHDPD 2019
Query: 248 LGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKA 295
G N + Y ++ +G++ L E PS T + A
Sbjct: 2020 AGANGHVTYYLGAGTAGAFLLEPSSGELRTAAALDREQCPSYTFSVSA 2067
Score = 83.4 bits (197), Expect = 3e-15
Identities = 97/393 (24%), Positives = 148/393 (37%), Gaps = 29/393 (7%)
Query: 139 GPHSALHYAVLPGPHSEYLGFENELEPIIVVK-KPLDFETVNNFTIKLRVQDQGSPPLYS 197
G + + Y++L G + I V + LDFE + L+ + G+ ++
Sbjct: 2233 GTNGPITYSILSGNEKGTFSIQPSTGAITVRSAEGLDFEVSPRLRLVLQAESGGA---FA 2289
Query: 198 DTTLQVTVLDADDQNPKFTYEHYTALLPDDAE-EGTFLTTSPGPISAADQDLGINAPLQY 256
T L +T+ DA+D P+F HY A LP+ EG L + A D D G + Y
Sbjct: 2290 FTVLTLTLQDANDNAPRFLRPHYVAFLPESRPLEGPLLQ-----VEADDLDQGSGGQISY 2344
Query: 257 SSTGDH--KQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXX 314
S + L V+ TG + T L E+ +VL AT +P ATL
Sbjct: 2345 SLAASQPARGLFHVDPTTGTITTTAILDREIWAETRLVLMATDRGSPALVGSATLTVMVI 2404
Query: 315 XXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYV-SDRSF 373
+ + VSE A GS + +T + P+ +YV S
Sbjct: 2405 DTNDNRPTI------PQPWELRVSEDALLGSEIAQVT----GNDVDSGPVLWYVLSPSGP 2454
Query: 374 LDKFAINN-AGEVILRRSLDYETTSNYFYQVMVTDSISNDTASINISVEDVNEWEPRFRH 432
D F++ G V L LD+E Y Q++ D A++ + VEDVN+ P F
Sbjct: 2455 QDPFSVGRYGGRVSLTGPLDFEQCDRYQLQLLAHDGPHEGRANLTVLVEDVNDNAPAFSQ 2514
Query: 433 PQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGDAGTLALSLAGQHARMFYINASGDLF--L 490
Y+ G G ++ LA +G LF +
Sbjct: 2515 SLYQVMLLEHTPPGSAILSVSATD---RDSGANGHISYHLASPADGFSVDPNNGTLFTIV 2571
Query: 491 REEAIGNLNSSSLHLVATAIDSGIPPRQTSVPV 523
A+G+ S ++ +V A D G P R V
Sbjct: 2572 GTVALGHDGSGAVDVVLEARDHGAPGRAARATV 2604
Score = 82.6 bits (195), Expect = 6e-15
Identities = 87/351 (24%), Positives = 142/351 (40%), Gaps = 29/351 (8%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLL---RALDREE 67
+SE P G ++ +SV+ D + + L+ + + L+ R LDREE
Sbjct: 511 VSEAAPPGQLVARISVSDPDDGDFAHVNVSLEGGEGHFALSTQDSVIYLVCVARRLDREE 570
Query: 68 KIGPSNVYVNVRCDRRRTTDPSFVIPVS--VRVWDVNDNAPQWEGAPYAVR-VSETXXXX 124
+ + Y N+R + P + + V DVNDNAP ++ Y + E
Sbjct: 571 R----DAY-NLRVTATDSGSPPLRAEAAFVLHVTDVNDNAPAFDRQLYRPEPLPEVALPG 625
Query: 125 XXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIK 184
D DQ G + + Y++ PG H+ + + II LD+E +
Sbjct: 626 SFVVRVTARDPDQ-GTNGQVTYSLAPGAHTHWFSID-PTSGIITTAASLDYELEPQPQLI 683
Query: 185 LRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGT-FLTTSPGPISA 243
+ D G PPL S T+ V + D +D P+F Y A LP+ + GT FL ++A
Sbjct: 684 VVATDGGLPPLASSATVSVALQDVNDNEPQFQRTFYNASLPEGTQPGTCFL-----QVTA 738
Query: 244 ADQDLGINAPLQYS-STG---DHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVD 299
D D G L YS G ++ +G V T+ L + PS + T VD
Sbjct: 739 TDADSGPFGLLSYSLGAGLGSSGSPPFRIDAHSGDVCTTRTLDRDQGPS-SFDFTVTAVD 797
Query: 300 NPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTL 350
++ + QF ++Y+ ++S + PG+ +L L
Sbjct: 798 GGGLKSMVYVKVFLSDENDNPP-----QFYPREYAASISAQSPPGTAVLRL 843
Score = 74.9 bits (176), Expect = 1e-12
Identities = 111/452 (24%), Positives = 171/452 (37%), Gaps = 49/452 (10%)
Query: 10 FISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIV---PGSKNLTLLRALDRE 66
F+ E P+ + + + G I+ L A G+ P + +T LDRE
Sbjct: 2315 FLPESRPLEGPLLQVEADDLDQGSGGQISYSLAASQPARGLFHVDPTTGTITTTAILDRE 2374
Query: 67 EKIGPSNVYVNVRCDRRRTTDPSFV--IPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXX 124
I V + DR P+ V ++V V D NDN P P+ +RVSE
Sbjct: 2375 --IWAETRLVLMATDRG---SPALVGSATLTVMVIDTNDNRPTIP-QPWELRVSEDALLG 2428
Query: 125 XXXXXXXXSDRDQPGPHSALHYAVLP-GPHSEYLGFENELEPIIVVKKPLDFETVNNFTI 183
+D D GP L Y + P GP + + + PLDFE + + +
Sbjct: 2429 SEIAQVTGNDVDS-GP--VLWYVLSPSGPQDPFS--VGRYGGRVSLTGPLDFEQCDRYQL 2483
Query: 184 KLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISA 243
+L D P L V V D +D P F+ Y +L + G+ + + +SA
Sbjct: 2484 QLLAHDG---PHEGRANLTVLVEDVNDNAPAFSQSLYQVMLLEHTPPGSAILS----VSA 2536
Query: 244 ADQDLGINAPLQY--SSTGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNP 301
D+D G N + Y +S D + N + T L + +V +VL+A P
Sbjct: 2537 TDRDSGANGHISYHLASPADGFSVDPNNGTLFTIVGTVALGHDGSGAVDVVLEARDHGAP 2596
Query: 302 DRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRE 361
R A AT+ FT Y V+E PGS LLTL +
Sbjct: 2597 GRAARATVHVQLQDQNDHAPS-----FTLSHYRVAVTEDLPPGSTLLTLEATDADGSRSH 2651
Query: 362 SPLQFYVSD----RSFLDKFAINNAGE-----------VILRRSLDYETTSNYFYQVMVT 406
+ + + + R F + + AGE ++L LD+E+ + Y V
Sbjct: 2652 AAVDYSIISGNWGRVFQLEPRLAEAGESAGPGPRALGCLVLLEPLDFESLTQYNLTVAAA 2711
Query: 407 D---SISNDTASINISVEDVNEWEPRFRHPQY 435
D + + ++V DVN+ P F Y
Sbjct: 2712 DRGQPPQSSVVPVTVTVLDVNDNPPVFTRASY 2743
Score = 73.7 bits (173), Expect = 3e-12
Identities = 83/382 (21%), Positives = 149/382 (39%), Gaps = 21/382 (5%)
Query: 60 LRALDREEKIGPSNVYVNVRCDRRRTTDP--SFVIPVSVRVWDVNDNAPQWEGAPYAVRV 117
+R LDRE + P+ +R + R P S + ++V V D ND+AP + Y+V V
Sbjct: 1946 MRPLDRE--VEPA---FQLRIEARDGGQPALSATLLLTVTVLDANDHAPAFPVPAYSVEV 2000
Query: 118 SETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFET 177
E D D G + + Y + G +L + E + LD E
Sbjct: 2001 PEDVPAGTLLLQLQAHDPDA-GANGHVTYYLGAGTAGAFLLEPSSGE--LRTAAALDREQ 2057
Query: 178 VNNFTIKLRVQDQGSP-PLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTT 236
++T + D + PL + ++ +TV D +D P F LP + T
Sbjct: 2058 CPSYTFSVSAVDGAAAGPLSTTVSVTITVRDVNDHAPTFPTSPLRLRLPRPGPSFSTPTL 2117
Query: 237 SPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKAT 296
+ + A D+D G NA + Y G V+ TG++ + +A + + AT
Sbjct: 2118 ALATLRAEDRDAGANASILYRLAGTPPPGTTVDSYTGEIRVARSPVALGPRDRVLFIVAT 2177
Query: 297 QVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQN 356
+ P R A + +F + T+ E A PG+ +++ V +
Sbjct: 2178 DLGRPARSATGVIIVGLQGEAERGP-----RFPRASSEATIRENAPPGTPIVSPRAV--H 2230
Query: 357 TEFRESPLQFYVSDRSFLDKFAIN-NAGEVILR--RSLDYETTSNYFYQVMVTDSISNDT 413
P+ + + + F+I + G + +R LD+E + + +
Sbjct: 2231 AGGTNGPITYSILSGNEKGTFSIQPSTGAITVRSAEGLDFEVSPRLRLVLQAESGGAFAF 2290
Query: 414 ASINISVEDVNEWEPRFRHPQY 435
+ ++++D N+ PRF P Y
Sbjct: 2291 TVLTLTLQDANDNAPRFLRPHY 2312
Score = 67.3 bits (157), Expect = 2e-10
Identities = 102/424 (24%), Positives = 162/424 (38%), Gaps = 31/424 (7%)
Query: 18 GSIIGTLSVNGDPSEDLGDITLRL---QEKGAAVGIVPGSKNLTLLRALDREEKIGPSNV 74
GS++G+++ +P+ +G +T L + + S L L R LD E GP
Sbjct: 1484 GSLLGSVAAP-EPA-GVGALTYTLVGGADPEGTFALDAASGRLYLARPLDFEA--GPPWR 1539
Query: 75 YVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSD 134
+ VR + ++ V V+V D N++AP + P A+ + E SD
Sbjct: 1540 ALTVRAEGPGGAGAR-LLRVQVQVQDENEHAPAFARDPLALALPENPEPGAALYTFRASD 1598
Query: 135 RDQPGPHSALHYAVL-PGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQ--- 190
D PGP+S + Y +L P L + + + LD ET + + D+
Sbjct: 1599 ADGPGPNSDVRYRLLRQEPPVPALRLDAR-TGALSAPRGLDRETTPALLLLVEATDRPAN 1657
Query: 191 GSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGI 250
S + + +V V D +D P F LP+D G + + A D DLG
Sbjct: 1658 ASRRRAARVSARVFVTDENDNAPVFA-SPSRVRLPEDQPPG----PAALHVVARDPDLGE 1712
Query: 251 NAPLQYSSTGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLX 310
A + Y ++ TG ++ + L E + + A+ +P R A L
Sbjct: 1713 AARVSYRLASGGDGHFRLHSSTGALSVVRPLDREQRAEHVLTVVASDHGSPPRSATQVLT 1772
Query: 311 XXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSD 370
F Q++YS + E PG+ LLTL + VS
Sbjct: 1773 VSVADVNDEAPT-----FQQQEYSVLLRENNPPGTSLLTLRATDPDVGANGQVTYGGVSS 1827
Query: 371 RSF-LDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSISNDT---ASINISVEDVNEW 426
SF LD + G + R+LD E V D S ++ ++VED N+
Sbjct: 1828 ESFSLDP----DTGVLTTLRALDREEQEEINLTVYAQDRGSPPQLTHVTVRVAVEDENDH 1883
Query: 427 EPRF 430
P F
Sbjct: 1884 APTF 1887
Score = 65.3 bits (152), Expect = 9e-10
Identities = 99/433 (22%), Positives = 168/433 (38%), Gaps = 23/433 (5%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
+ V + D+ND+AP + + Y VSE+ SD D G + A+ Y +
Sbjct: 377 LDVTLLDINDHAPAFNQSRYHAVVSESLAPGSPVLQVFASDADA-GVNGAVTYEINRRQS 435
Query: 154 SEYLGFENELEP-IIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQN 212
F + ++ +++PLDFE + ++ +D G+ P + V V DA+D
Sbjct: 436 EGDGPFSIDAHTGLLQLERPLDFEQRRVHELVVQARDGGAHPELGSAFVTVHVRDANDNQ 495
Query: 213 PKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDT 272
P T +A E IS +D D G A + S G + +D+
Sbjct: 496 PSMTVIFLSADGSPQVSEAAPPGQLVARISVSDPDDGDFAHVNVSLEGGEGHFALSTQDS 555
Query: 273 --GQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQ 330
V ++L E + + + AT +P A A F +
Sbjct: 556 VIYLVCVARRLDREERDAYNLRVTATDSGSPPLRAEAAFVLHVTDVNDNAPA-----FDR 610
Query: 331 KQY-STTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILR 388
+ Y + E A PGS ++ +T + + + + ++ + F+I+ +G +
Sbjct: 611 QLYRPEPLPEVALPGSFVVRVTARDPD-QGTNGQVTYSLAPGAHTHWFSIDPTSGIITTA 669
Query: 389 RSLDYETTSNYFYQVMVTDS---ISNDTASINISVEDVNEWEPRFRHPQYEFEXXXXXXX 445
SLDYE V+ TD +A+++++++DVN+ EP+F Q F
Sbjct: 670 ASLDYELEPQPQLIVVATDGGLPPLASSATVSVALQDVNDNEPQF---QRTFYNASLPEG 726
Query: 446 XXXXXXXXXXXXXVAHDGDAGTLALSL-AG---QHARMFYINA-SGDLFLREEAIGNLNS 500
A G G L+ SL AG + F I+A SGD+ +
Sbjct: 727 TQPGTCFLQVTATDADSGPFGLLSYSLGAGLGSSGSPPFRIDAHSGDVCTTRTLDRDQGP 786
Query: 501 SSLHLVATAIDSG 513
SS TA+D G
Sbjct: 787 SSFDFTVTAVDGG 799
Score = 63.7 bits (148), Expect = 3e-09
Identities = 77/363 (21%), Positives = 138/363 (38%), Gaps = 31/363 (8%)
Query: 171 KPLDFETVNNFTIKLRVQ-DQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAE 229
+PLD E + ++L V+ G PP ++ ++V + D +D +P F T LLP +
Sbjct: 986 RPLDRELLGP-VLELEVRAGSGVPPAFAVARVRVLLDDVNDNSPAFPAPEDTVLLPPNTA 1044
Query: 230 EGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLIAELDPSV 289
GT + T + A D D G+N+ + ++ V+ TG V + L P+
Sbjct: 1045 PGTPIYT----LRALDPDSGVNSRVTFTLLAGGGGAFTVDPTTGHVRLMRPLGPSGGPAH 1100
Query: 290 TIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLT 349
+ L+A +P R + L +F Y + G + G+ +L
Sbjct: 1101 ELELEARDGGSPPRTSHFRLRVVVQDVGTRGLAP---RFNSPTYRVDLPSGTTAGTQVLQ 1157
Query: 350 LTTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTDS 408
+ + P+ ++++ F + +G + +R +LD E Y +VM
Sbjct: 1158 VQAQAPD----GGPITYHLAAEGASSPFGLEPQSGWLWVRAALDREAQELYILKVMAVSG 1213
Query: 409 ISND------TASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAHD 462
+ TA++ +S+ + NE PR E A D
Sbjct: 1214 SKAELGQQTGTATVRVSILNQNEHSPRLS------EDPTFLAVAENQPPGTSVGRVFATD 1267
Query: 463 GDAG-----TLALSLAGQHARMFYINASGDLFLREEAIGNLNSSSLHLVATAIDSGIPPR 517
D+G T +L + ++ F I+ + + SS L+ D G PPR
Sbjct: 1268 RDSGPNGRLTYSLQQLSEDSKAFRIHPQTGEVTTLQTLDREQQSSYQLLVQVQDGGSPPR 1327
Query: 518 QTS 520
T+
Sbjct: 1328 STT 1330
Score = 58.4 bits (135), Expect = 1e-07
Identities = 67/272 (24%), Positives = 109/272 (40%), Gaps = 25/272 (9%)
Query: 11 ISEDTPIGS-IIGTLSVNGDPS-EDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEK 68
+ EDTP+G+ ++ + + DP L T+ + + S L L ALD E +
Sbjct: 2747 VPEDTPVGAELLHVEASDADPGPHGLVRFTVSSGDPSGLFELDESSGTLRLAHALDCETQ 2806
Query: 69 IGPSNVYVNVRCDRRRTTDPS---FVI-PVSVRVWDVNDNAPQWEGAPYAVRVSETXXXX 124
V + DP+ F + PV++ V DVND+ P + + V+E
Sbjct: 2807 ARHQLVV--------QAADPAGAHFALAPVTIEVQDVNDHGPAFPLNLLSTSVAENQPPG 2858
Query: 125 XXXXXXXXSDRDQPGPHSALHYAVL---PGPHSEYLGFENELEPIIVVKKPLDFETVNNF 181
D D G L Y++L PGP N + + P D+E +F
Sbjct: 2859 TLVTTLHAIDGDA-GAFGRLRYSLLEAGPGPEGREAFALNSSTGELRARVPFDYEHTESF 2917
Query: 182 TIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPI 241
+ + D G+ L + T+ V V D+ +P F + +P+ A G L G +
Sbjct: 2918 RLLVGAADAGN--LSASVTVSVLVTGEDEYDPVFLAPAFHFQVPEGARRGHSL----GHV 2971
Query: 242 SAADQDLGINAPLQYSSTGDHKQLIVVNKDTG 273
A D+D G + + Y S +N+ TG
Sbjct: 2972 QATDEDGGADGLVLY-SLATSSPYFGINQTTG 3002
Score = 52.0 bits (119), Expect = 9e-06
Identities = 54/205 (26%), Positives = 85/205 (41%), Gaps = 15/205 (7%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQ---EKGAAVGIVPGSKNLTLLRALDREE 67
++E+ P G+ +G + S G +T LQ E A I P + +T L+ LDRE+
Sbjct: 1250 VAENQPPGTSVGRVFATDRDSGPNGRLTYSLQQLSEDSKAFRIHPQTGEVTTLQTLDREQ 1309
Query: 68 KIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQW------EGAPYAVRVSETX 121
+ S+ + V+ + S V V V D+NDN+P + G ++V +
Sbjct: 1310 Q---SSYQLLVQVQDGGSPPRSTTGTVHVAVLDLNDNSPTFLQASGAAGGGLPIQVPDRV 1366
Query: 122 XXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNF 181
D D+ G + + Y L GP SE ++ PL ++
Sbjct: 1367 PPGTLVTTLQAKDPDE-GENGTILYT-LTGPGSELFSLHPHSGELLTAA-PLIRAERPHY 1423
Query: 182 TIKLRVQDQGSPPLYSDTTLQVTVL 206
+ L DQGSPP + L V VL
Sbjct: 1424 VLTLSAHDQGSPPRSASLQLLVQVL 1448
Score = 50.8 bits (116), Expect = 2e-05
Identities = 59/233 (25%), Positives = 95/233 (40%), Gaps = 12/233 (5%)
Query: 54 SKNLTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPY 113
S ++ R LDR++ GPS+ V ++ V V + D NDN PQ+ Y
Sbjct: 771 SGDVCTTRTLDRDQ--GPSSFDFTVTAVDGGGLKS--MVYVKVFLSDENDNPPQFYPREY 826
Query: 114 AVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPL 173
A +S D DQ G H L Y +L G +S L +E ++ V PL
Sbjct: 827 AASISAQSPPGTAVLRLRAHDPDQ-GSHGRLSYHILAG-NSPPLFTLDEQSGLLTVAWPL 884
Query: 174 DFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTF 233
+ +++ +D G + ++++ P F Y +P+D G
Sbjct: 885 ARRANSVVQLEIGAEDGGGLQAEPSARVDISIVPGTPTPPIFEQLQYVFSVPEDVAPG-- 942
Query: 234 LTTSPGPISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAEL 285
TS G + A + G AP+ S S GD + L ++ +G + + L EL
Sbjct: 943 --TSVGIVQAHNPP-GRLAPVTLSLSGGDPRGLFSLDAVSGLLQTLRPLDREL 992
Score = 44.4 bits (100), Expect = 0.002
Identities = 78/352 (22%), Positives = 134/352 (38%), Gaps = 28/352 (7%)
Query: 11 ISEDTPIGS-IIGTLSVNGDPSEDLGDITLRL---QEKGAAVGIVPGSKNLTLLRALDRE 66
I E+ P G+ I+ +V+ + G IT + EKG I P + +T+ A +
Sbjct: 2213 IRENAPPGTPIVSPRAVHAGGTN--GPITYSILSGNEKGT-FSIQPSTGAITVRSAEGLD 2269
Query: 67 EKIGPSNVYVNVRCDRRRTTDPSFVIPV-SVRVWDVNDNAPQWEGAPYAVRVSETXXXXX 125
++ P +R + + +F V ++ + D NDNAP++ Y + E+
Sbjct: 2270 FEVSP-----RLRLVLQAESGGAFAFTVLTLTLQDANDNAPRFLRPHYVAFLPESRPLEG 2324
Query: 126 XXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKL 185
D DQ G + Y++ + L + I LD E + L
Sbjct: 2325 PLLQVEADDLDQ-GSGGQISYSLAASQPARGLFHVDPTTGTITTTAILDREIWAETRLVL 2383
Query: 186 RVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAAD 245
D+GSP L TL V V+D +D P + + + +DA L + ++ D
Sbjct: 2384 MATDRGSPALVGSATLTVMVIDTNDNRPTIP-QPWELRVSEDA----LLGSEIAQVTGND 2438
Query: 246 QDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYA 305
D G S +G + V + G+V+ T L E + L A + R
Sbjct: 2439 VDSGPVLWYVLSPSGP-QDPFSVGRYGGRVSLTGPLDFEQCDRYQLQLLAHDGPHEGRAN 2497
Query: 306 LATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNT 357
L L F+Q Y + E PGS +L+++ +++
Sbjct: 2498 LTVLVEDVNDNAPA--------FSQSLYQVMLLEHTPPGSAILSVSATDRDS 2541
>AL031597-2|CAI23555.1| 3014|Homo sapiens cadherin, EGF LAG
seven-pass G-type receptor 1 (flamingo homolog,
Drosophila) protein.
Length = 3014
Score = 107 bits (258), Expect = 1e-22
Identities = 102/391 (26%), Positives = 160/391 (40%), Gaps = 29/391 (7%)
Query: 63 LDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXX 122
LDREE + V R S V + V D NDN PQ+ Y V+V E
Sbjct: 415 LDREEA-AEYQLLVEANDQGRNPGPLSATATVYIEVEDENDNYPQFSEQNYVVQVPEDVG 473
Query: 123 XXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFT 182
+DRDQ G ++A+HY++L G + + + L I+ V PLDFE V ++
Sbjct: 474 LNTAVLRVQATDRDQ-GQNAAIHYSILSGNVAGQF-YLHSLSGILDVINPLDFEDVQKYS 531
Query: 183 IKLRVQDQGSPPLY-SDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPI 241
+ ++ QD G PPL S + V VLD +D P F + A + ++ G + I
Sbjct: 532 LSIKAQDGGRPPLINSSGVVSVQVLDVNDNEPIFVSSPFQATVLENVPLGYPVV----HI 587
Query: 242 SAADQDLGINAPLQYSSTGDHKQLIVVNKDTG--QVAATKQLIAELDPSVTIVLKATQVD 299
A D D G NA L Y D + G A T ++ S + ++D
Sbjct: 588 QAVDADSGENARLHYRLV-DTASTFLGGGSAGPKNPAPTPDFPFQIHNSSGWITVCAELD 646
Query: 300 NP--DRYALATLXXXXXXXXXXXXXXXXLQ----------FTQKQYSTTVSEGASPGSVL 347
+ Y+ + FTQ Y ++E A+ GS +
Sbjct: 647 REEVEHYSFGVEAVDHGSPPMSSSTSVSITVLDVNDNDPVFTQPTYELRLNEDAAVGSSV 706
Query: 348 LTLTTVPQNTEFRESPLQFYVSDRSFLDKFAINN---AGEVILRRSLDYETTSNYFYQVM 404
LTL ++ S + + ++ + ++FA+++ G + L LDY+ Y V
Sbjct: 707 LTLQARDRDA---NSVITYQLTGGNTRNRFALSSQRGGGLITLALPLDYKQEQQYVLAVT 763
Query: 405 VTDSISNDTASINISVEDVNEWEPRFRHPQY 435
+D + TA + I+V D N P F+ Y
Sbjct: 764 ASDGTRSHTAHVLINVTDANTHRPVFQSSHY 794
Score = 97.9 bits (233), Expect = 1e-19
Identities = 99/418 (23%), Positives = 164/418 (39%), Gaps = 18/418 (4%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEKIG 70
+SED P+G+ I TLS N + + + IT +Q+ I P S + + LD E ++
Sbjct: 798 VSEDRPVGTSIATLSANDEDTGENARITYVIQDPVPQFRIDPDSGTMYTMMELDYENQVA 857
Query: 71 PSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXX 130
+ + + S + + + D NDNAPQ+ Y + E
Sbjct: 858 YT---LTIMAQDNGIPQKSDTTTLEILILDANDNAPQFLWDFYQGSIFEDAPPSTSILQV 914
Query: 131 XXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQ 190
+DRD GP+ L Y G + + +I ++ LD E V + + D+
Sbjct: 915 SATDRDS-GPNGRLLYTFQGGDDGDGDFYIEPTSGVIRTQRRLDRENVAVYNLWALAVDR 973
Query: 191 GSP-PLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLG 249
GSP PL + +QVT+LD +D P F + + ++ G+ + I A D D G
Sbjct: 974 GSPTPLSASVEIQVTILDINDNAPMFEKDELELFVEENNPVGSVV----AKIRANDPDEG 1029
Query: 250 INAPLQYSST-GDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALAT 308
NA + Y GD + ++ G + A +L E+ +V++AT R AT
Sbjct: 1030 PNAQIMYQIVEGDMRHFFQLDLLNGDLRAMVELDFEVRREYVLVVQATSAPLVSR---AT 1086
Query: 309 LXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYV 368
+ Q Y T S G + +P + L +
Sbjct: 1087 VHILLVDQNDNPPVLPDFQILFNNYVTNKSNSFPTG----VIGCIPAHDPDVSDSLNYTF 1142
Query: 369 SDRSFLDKFAINNA-GEVILRRSLDYETTSNYFYQVMVTDSISNDTASINISVEDVNE 425
+ L ++ A GE+ L R LD +V V+D I + TA + V + +
Sbjct: 1143 VQGNELRLLLLDPATGELQLSRDLDNNRPLEALMEVSVSDGIHSVTAFCTLRVTIITD 1200
Score = 97.5 bits (232), Expect = 2e-19
Identities = 108/454 (23%), Positives = 178/454 (39%), Gaps = 43/454 (9%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVL---- 149
VSV+V DVNDN P + +P+ V E D D G ++ LHY ++
Sbjct: 551 VSVQVLDVNDNEPIFVSSPFQATVLENVPLGYPVVHIQAVDADS-GENARLHYRLVDTAS 609
Query: 150 ------------PGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYS 197
P P ++ + I V LD E V +++ + D GSPP+ S
Sbjct: 610 TFLGGGSAGPKNPAPTPDFPFQIHNSSGWITVCAELDREEVEHYSFGVEAVDHGSPPMSS 669
Query: 198 DTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYS 257
T++ +TVLD +D +P FT Y L +DA G+ + T + A D+D N+ + Y
Sbjct: 670 STSVSITVLDVNDNDPVFTQPTYELRLNEDAAVGSSVLT----LQARDRD--ANSVITYQ 723
Query: 258 STGDH-KQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXX 316
TG + + ++ G T L + VL T D + L
Sbjct: 724 LTGGNTRNRFALSSQRGGGLITLALPLDYKQEQQYVLAVTASDGTRSHTAHVLINVTDAN 783
Query: 317 XXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDK 376
F Y+ +VSE G+ + TL+ ++T + + + + D + +
Sbjct: 784 THRPV------FQSSHYTVSVSEDRPVGTSIATLSANDEDTG-ENARITYVIQDP--VPQ 834
Query: 377 FAIN-NAGEVILRRSLDYETTSNYFYQVMVTDS---ISNDTASINISVEDVNEWEPRFRH 432
F I+ ++G + LDYE Y +M D+ +DT ++ I + D N+ P+F
Sbjct: 835 FRIDPDSGTMYTMMELDYENQVAYTLTIMAQDNGIPQKSDTTTLEILILDANDNAPQF-- 892
Query: 433 PQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGDAGTLALSLAG--QHARMFYINASGDLFL 490
++F G G L + G FYI + +
Sbjct: 893 -LWDFYQGSIFEDAPPSTSILQVSATDRDSGPNGRLLYTFQGGDDGDGDFYIEPTSGVIR 951
Query: 491 REEAIGNLNSSSLHLVATAIDSGIP-PRQTSVPV 523
+ + N + +L A A+D G P P SV +
Sbjct: 952 TQRRLDRENVAVYNLWALAVDRGSPTPLSASVEI 985
Score = 77.4 bits (182), Expect = 2e-13
Identities = 88/386 (22%), Positives = 151/386 (39%), Gaps = 25/386 (6%)
Query: 57 LTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVR 116
+T+ LDREE + V + S VS+ V DVNDN P + Y +R
Sbjct: 639 ITVCAELDREEV---EHYSFGVEAVDHGSPPMSSSTSVSITVLDVNDNDPVFTQPTYELR 695
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENEL-EPIIVVKKPLDF 175
++E DRD +S + Y + G ++ +I + PLD+
Sbjct: 696 LNEDAAVGSSVLTLQARDRD---ANSVITYQLTGGNTRNRFALSSQRGGGLITLALPLDY 752
Query: 176 ETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLT 235
+ + + + D G+ + + VT DA+ P F HYT + +D GT +
Sbjct: 753 KQEQQYVLAVTASD-GTRSHTAHVLINVT--DANTHRPVFQSSHYTVSVSEDRPVGTSIA 809
Query: 236 TSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKA 295
T +SA D+D G NA + Y D ++ D+G + +L E + T+ + A
Sbjct: 810 T----LSANDEDTGENARITY-VIQDPVPQFRIDPDSGTMYTMMELDYENQVAYTLTIMA 864
Query: 296 TQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQ 355
P + TL QF Y ++ E A P + +L ++ +
Sbjct: 865 QDNGIPQKSDTTTLEILILDANDNAP-----QFLWDFYQGSIFEDAPPSTSILQVSATDR 919
Query: 356 NTEFRESPL-QFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSIS---- 410
++ L F D D + +G + +R LD E + Y + D S
Sbjct: 920 DSGPNGRLLYTFQGGDDGDGDFYIEPTSGVIRTQRRLDRENVAVYNLWALAVDRGSPTPL 979
Query: 411 NDTASINISVEDVNEWEPRFRHPQYE 436
+ + I +++ D+N+ P F + E
Sbjct: 980 SASVEIQVTILDINDNAPMFEKDELE 1005
Score = 75.4 bits (177), Expect = 9e-13
Identities = 59/197 (29%), Positives = 91/197 (46%), Gaps = 12/197 (6%)
Query: 63 LDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXX 122
LDRE K + V+ T S ++V V D ND++P +E + Y RV E
Sbjct: 311 LDRETK---ETHVLRVKAVDYSTPPRSATTYITVLVKDTNDHSPVFEQSEYRERVRENLE 367
Query: 123 XXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFT 182
SDRD P ++ L Y VL G + NE ++ + LD E +
Sbjct: 368 VGYEVLTIRASDRDSP-INANLRYRVLGGAWDVFQ--LNESSGVVSTRAVLDREEAAEYQ 424
Query: 183 IKLRVQDQG-SP-PLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGP 240
+ + DQG +P PL + T+ + V D +D P+F+ ++Y +P+D L T+
Sbjct: 425 LLVEANDQGRNPGPLSATATVYIEVEDENDNYPQFSEQNYVVQVPEDVG----LNTAVLR 480
Query: 241 ISAADQDLGINAPLQYS 257
+ A D+D G NA + YS
Sbjct: 481 VQATDRDQGQNAAIHYS 497
Score = 66.5 bits (155), Expect = 4e-10
Identities = 61/265 (23%), Positives = 117/265 (44%), Gaps = 17/265 (6%)
Query: 173 LDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGT 232
LD ET ++++ D +PP + T + V V D +D +P F Y + ++ E G
Sbjct: 311 LDRETKETHVLRVKAVDYSTPPRSATTYITVLVKDTNDHSPVFEQSEYRERVRENLEVGY 370
Query: 233 FLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIV 292
+ T I A+D+D INA L+Y G + +N+ +G V+ L E ++
Sbjct: 371 EVLT----IRASDRDSPINANLRYRVLGGAWDVFQLNESSGVVSTRAVLDREEAAEYQLL 426
Query: 293 LKAT-QVDNPDRY-ALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTL 350
++A Q NP A AT+ QF+++ Y V E + +L +
Sbjct: 427 VEANDQGRNPGPLSATATVYIEVEDENDNYP-----QFSEQNYVVQVPEDVGLNTAVLRV 481
Query: 351 TTVPQNTEFRESPLQFYVSDRSFLDKFAINN-AGEVILRRSLDYETTSNYFYQVMVTDS- 408
++ + + + + + + + +F +++ +G + + LD+E Y + D
Sbjct: 482 QATDRD-QGQNAAIHYSILSGNVAGQFYLHSLSGILDVINPLDFEDVQKYSLSIKAQDGG 540
Query: 409 ---ISNDTASINISVEDVNEWEPRF 430
+ N + +++ V DVN+ EP F
Sbjct: 541 RPPLINSSGVVSVQVLDVNDNEPIF 565
Score = 40.3 bits (90), Expect = 0.030
Identities = 48/228 (21%), Positives = 87/228 (38%), Gaps = 13/228 (5%)
Query: 214 KFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTG 273
KF +Y L ++ GT + + ++ ++ ++ + ++ TG
Sbjct: 244 KFPMPNYQVALFENEPAGTLILQLHAHYTIEGEEERVSYYMEGLFDERSRGYFRIDSATG 303
Query: 274 QVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQY 333
V+ L E + + +KA P R A + F Q +Y
Sbjct: 304 AVSTDSVLDRETKETHVLRVKAVDYSTPPRSATTYITVLVKDTNDHSPV-----FEQSEY 358
Query: 334 STTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRS-LD 392
V E G +LT+ +++ + L++ V ++ D F +N + V+ R+ LD
Sbjct: 359 RERVRENLEVGYEVLTIRASDRDSPINAN-LRYRVLGGAW-DVFQLNESSGVVSTRAVLD 416
Query: 393 YETTSNYFYQVMVTDSISND-----TASINISVEDVNEWEPRFRHPQY 435
E + Y V D N TA++ I VED N+ P+F Y
Sbjct: 417 REEAAEYQLLVEANDQGRNPGPLSATATVYIEVEDENDNYPQFSEQNY 464
>AL031588-3|CAI19319.1| 3014|Homo sapiens cadherin, EGF LAG
seven-pass G-type receptor 1 (flamingo homolog,
Drosophila) protein.
Length = 3014
Score = 107 bits (258), Expect = 1e-22
Identities = 102/391 (26%), Positives = 160/391 (40%), Gaps = 29/391 (7%)
Query: 63 LDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXX 122
LDREE + V R S V + V D NDN PQ+ Y V+V E
Sbjct: 415 LDREEA-AEYQLLVEANDQGRNPGPLSATATVYIEVEDENDNYPQFSEQNYVVQVPEDVG 473
Query: 123 XXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFT 182
+DRDQ G ++A+HY++L G + + + L I+ V PLDFE V ++
Sbjct: 474 LNTAVLRVQATDRDQ-GQNAAIHYSILSGNVAGQF-YLHSLSGILDVINPLDFEDVQKYS 531
Query: 183 IKLRVQDQGSPPLY-SDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPI 241
+ ++ QD G PPL S + V VLD +D P F + A + ++ G + I
Sbjct: 532 LSIKAQDGGRPPLINSSGVVSVQVLDVNDNEPIFVSSPFQATVLENVPLGYPVV----HI 587
Query: 242 SAADQDLGINAPLQYSSTGDHKQLIVVNKDTG--QVAATKQLIAELDPSVTIVLKATQVD 299
A D D G NA L Y D + G A T ++ S + ++D
Sbjct: 588 QAVDADSGENARLHYRLV-DTASTFLGGGSAGPKNPAPTPDFPFQIHNSSGWITVCAELD 646
Query: 300 NP--DRYALATLXXXXXXXXXXXXXXXXLQ----------FTQKQYSTTVSEGASPGSVL 347
+ Y+ + FTQ Y ++E A+ GS +
Sbjct: 647 REEVEHYSFGVEAVDHGSPPMSSSTSVSITVLDVNDNDPVFTQPTYELRLNEDAAVGSSV 706
Query: 348 LTLTTVPQNTEFRESPLQFYVSDRSFLDKFAINN---AGEVILRRSLDYETTSNYFYQVM 404
LTL ++ S + + ++ + ++FA+++ G + L LDY+ Y V
Sbjct: 707 LTLQARDRDA---NSVITYQLTGGNTRNRFALSSQRGGGLITLALPLDYKQEQQYVLAVT 763
Query: 405 VTDSISNDTASINISVEDVNEWEPRFRHPQY 435
+D + TA + I+V D N P F+ Y
Sbjct: 764 ASDGTRSHTAHVLINVTDANTHRPVFQSSHY 794
Score = 97.9 bits (233), Expect = 1e-19
Identities = 99/418 (23%), Positives = 164/418 (39%), Gaps = 18/418 (4%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEKIG 70
+SED P+G+ I TLS N + + + IT +Q+ I P S + + LD E ++
Sbjct: 798 VSEDRPVGTSIATLSANDEDTGENARITYVIQDPVPQFRIDPDSGTMYTMMELDYENQVA 857
Query: 71 PSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXX 130
+ + + S + + + D NDNAPQ+ Y + E
Sbjct: 858 YT---LTIMAQDNGIPQKSDTTTLEILILDANDNAPQFLWDFYQGSIFEDAPPSTSILQV 914
Query: 131 XXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQ 190
+DRD GP+ L Y G + + +I ++ LD E V + + D+
Sbjct: 915 SATDRDS-GPNGRLLYTFQGGDDGDGDFYIEPTSGVIRTQRRLDRENVAVYNLWALAVDR 973
Query: 191 GSP-PLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLG 249
GSP PL + +QVT+LD +D P F + + ++ G+ + I A D D G
Sbjct: 974 GSPTPLSASVEIQVTILDINDNAPMFEKDELELFVEENNPVGSVV----AKIRANDPDEG 1029
Query: 250 INAPLQYSST-GDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALAT 308
NA + Y GD + ++ G + A +L E+ +V++AT R AT
Sbjct: 1030 PNAQIMYQIVEGDMRHFFQLDLLNGDLRAMVELDFEVRREYVLVVQATSAPLVSR---AT 1086
Query: 309 LXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYV 368
+ Q Y T S G + +P + L +
Sbjct: 1087 VHILLVDQNDNPPVLPDFQILFNNYVTNKSNSFPTG----VIGCIPAHDPDVSDSLNYTF 1142
Query: 369 SDRSFLDKFAINNA-GEVILRRSLDYETTSNYFYQVMVTDSISNDTASINISVEDVNE 425
+ L ++ A GE+ L R LD +V V+D I + TA + V + +
Sbjct: 1143 VQGNELRLLLLDPATGELQLSRDLDNNRPLEALMEVSVSDGIHSVTAFCTLRVTIITD 1200
Score = 97.5 bits (232), Expect = 2e-19
Identities = 108/454 (23%), Positives = 178/454 (39%), Gaps = 43/454 (9%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVL---- 149
VSV+V DVNDN P + +P+ V E D D G ++ LHY ++
Sbjct: 551 VSVQVLDVNDNEPIFVSSPFQATVLENVPLGYPVVHIQAVDADS-GENARLHYRLVDTAS 609
Query: 150 ------------PGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYS 197
P P ++ + I V LD E V +++ + D GSPP+ S
Sbjct: 610 TFLGGGSAGPKNPAPTPDFPFQIHNSSGWITVCAELDREEVEHYSFGVEAVDHGSPPMSS 669
Query: 198 DTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYS 257
T++ +TVLD +D +P FT Y L +DA G+ + T + A D+D N+ + Y
Sbjct: 670 STSVSITVLDVNDNDPVFTQPTYELRLNEDAAVGSSVLT----LQARDRD--ANSVITYQ 723
Query: 258 STGDH-KQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXX 316
TG + + ++ G T L + VL T D + L
Sbjct: 724 LTGGNTRNRFALSSQRGGGLITLALPLDYKQEQQYVLAVTASDGTRSHTAHVLINVTDAN 783
Query: 317 XXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDK 376
F Y+ +VSE G+ + TL+ ++T + + + + D + +
Sbjct: 784 THRPV------FQSSHYTVSVSEDRPVGTSIATLSANDEDTG-ENARITYVIQDP--VPQ 834
Query: 377 FAIN-NAGEVILRRSLDYETTSNYFYQVMVTDS---ISNDTASINISVEDVNEWEPRFRH 432
F I+ ++G + LDYE Y +M D+ +DT ++ I + D N+ P+F
Sbjct: 835 FRIDPDSGTMYTMMELDYENQVAYTLTIMAQDNGIPQKSDTTTLEILILDANDNAPQF-- 892
Query: 433 PQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGDAGTLALSLAG--QHARMFYINASGDLFL 490
++F G G L + G FYI + +
Sbjct: 893 -LWDFYQGSIFEDAPPSTSILQVSATDRDSGPNGRLLYTFQGGDDGDGDFYIEPTSGVIR 951
Query: 491 REEAIGNLNSSSLHLVATAIDSGIP-PRQTSVPV 523
+ + N + +L A A+D G P P SV +
Sbjct: 952 TQRRLDRENVAVYNLWALAVDRGSPTPLSASVEI 985
Score = 77.4 bits (182), Expect = 2e-13
Identities = 88/386 (22%), Positives = 151/386 (39%), Gaps = 25/386 (6%)
Query: 57 LTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVR 116
+T+ LDREE + V + S VS+ V DVNDN P + Y +R
Sbjct: 639 ITVCAELDREEV---EHYSFGVEAVDHGSPPMSSSTSVSITVLDVNDNDPVFTQPTYELR 695
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENEL-EPIIVVKKPLDF 175
++E DRD +S + Y + G ++ +I + PLD+
Sbjct: 696 LNEDAAVGSSVLTLQARDRD---ANSVITYQLTGGNTRNRFALSSQRGGGLITLALPLDY 752
Query: 176 ETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLT 235
+ + + + D G+ + + VT DA+ P F HYT + +D GT +
Sbjct: 753 KQEQQYVLAVTASD-GTRSHTAHVLINVT--DANTHRPVFQSSHYTVSVSEDRPVGTSIA 809
Query: 236 TSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKA 295
T +SA D+D G NA + Y D ++ D+G + +L E + T+ + A
Sbjct: 810 T----LSANDEDTGENARITY-VIQDPVPQFRIDPDSGTMYTMMELDYENQVAYTLTIMA 864
Query: 296 TQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQ 355
P + TL QF Y ++ E A P + +L ++ +
Sbjct: 865 QDNGIPQKSDTTTLEILILDANDNAP-----QFLWDFYQGSIFEDAPPSTSILQVSATDR 919
Query: 356 NTEFRESPL-QFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSIS---- 410
++ L F D D + +G + +R LD E + Y + D S
Sbjct: 920 DSGPNGRLLYTFQGGDDGDGDFYIEPTSGVIRTQRRLDRENVAVYNLWALAVDRGSPTPL 979
Query: 411 NDTASINISVEDVNEWEPRFRHPQYE 436
+ + I +++ D+N+ P F + E
Sbjct: 980 SASVEIQVTILDINDNAPMFEKDELE 1005
Score = 75.4 bits (177), Expect = 9e-13
Identities = 59/197 (29%), Positives = 91/197 (46%), Gaps = 12/197 (6%)
Query: 63 LDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXX 122
LDRE K + V+ T S ++V V D ND++P +E + Y RV E
Sbjct: 311 LDRETK---ETHVLRVKAVDYSTPPRSATTYITVLVKDTNDHSPVFEQSEYRERVRENLE 367
Query: 123 XXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFT 182
SDRD P ++ L Y VL G + NE ++ + LD E +
Sbjct: 368 VGYEVLTIRASDRDSP-INANLRYRVLGGAWDVFQ--LNESSGVVSTRAVLDREEAAEYQ 424
Query: 183 IKLRVQDQG-SP-PLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGP 240
+ + DQG +P PL + T+ + V D +D P+F+ ++Y +P+D L T+
Sbjct: 425 LLVEANDQGRNPGPLSATATVYIEVEDENDNYPQFSEQNYVVQVPEDVG----LNTAVLR 480
Query: 241 ISAADQDLGINAPLQYS 257
+ A D+D G NA + YS
Sbjct: 481 VQATDRDQGQNAAIHYS 497
Score = 66.5 bits (155), Expect = 4e-10
Identities = 61/265 (23%), Positives = 117/265 (44%), Gaps = 17/265 (6%)
Query: 173 LDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGT 232
LD ET ++++ D +PP + T + V V D +D +P F Y + ++ E G
Sbjct: 311 LDRETKETHVLRVKAVDYSTPPRSATTYITVLVKDTNDHSPVFEQSEYRERVRENLEVGY 370
Query: 233 FLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIV 292
+ T I A+D+D INA L+Y G + +N+ +G V+ L E ++
Sbjct: 371 EVLT----IRASDRDSPINANLRYRVLGGAWDVFQLNESSGVVSTRAVLDREEAAEYQLL 426
Query: 293 LKAT-QVDNPDRY-ALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTL 350
++A Q NP A AT+ QF+++ Y V E + +L +
Sbjct: 427 VEANDQGRNPGPLSATATVYIEVEDENDNYP-----QFSEQNYVVQVPEDVGLNTAVLRV 481
Query: 351 TTVPQNTEFRESPLQFYVSDRSFLDKFAINN-AGEVILRRSLDYETTSNYFYQVMVTDS- 408
++ + + + + + + + +F +++ +G + + LD+E Y + D
Sbjct: 482 QATDRD-QGQNAAIHYSILSGNVAGQFYLHSLSGILDVINPLDFEDVQKYSLSIKAQDGG 540
Query: 409 ---ISNDTASINISVEDVNEWEPRF 430
+ N + +++ V DVN+ EP F
Sbjct: 541 RPPLINSSGVVSVQVLDVNDNEPIF 565
Score = 40.3 bits (90), Expect = 0.030
Identities = 48/228 (21%), Positives = 87/228 (38%), Gaps = 13/228 (5%)
Query: 214 KFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTG 273
KF +Y L ++ GT + + ++ ++ ++ + ++ TG
Sbjct: 244 KFPMPNYQVALFENEPAGTLILQLHAHYTIEGEEERVSYYMEGLFDERSRGYFRIDSATG 303
Query: 274 QVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQY 333
V+ L E + + +KA P R A + F Q +Y
Sbjct: 304 AVSTDSVLDRETKETHVLRVKAVDYSTPPRSATTYITVLVKDTNDHSPV-----FEQSEY 358
Query: 334 STTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRS-LD 392
V E G +LT+ +++ + L++ V ++ D F +N + V+ R+ LD
Sbjct: 359 RERVRENLEVGYEVLTIRASDRDSPINAN-LRYRVLGGAW-DVFQLNESSGVVSTRAVLD 416
Query: 393 YETTSNYFYQVMVTDSISND-----TASINISVEDVNEWEPRFRHPQY 435
E + Y V D N TA++ I VED N+ P+F Y
Sbjct: 417 REEAAEYQLLVEANDQGRNPGPLSATATVYIEVEDENDNYPQFSEQNY 464
>AL021392-2|CAI20967.1| 3014|Homo sapiens cadherin, EGF LAG
seven-pass G-type receptor 1 (flamingo homolog,
Drosophila) protein.
Length = 3014
Score = 107 bits (258), Expect = 1e-22
Identities = 102/391 (26%), Positives = 160/391 (40%), Gaps = 29/391 (7%)
Query: 63 LDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXX 122
LDREE + V R S V + V D NDN PQ+ Y V+V E
Sbjct: 415 LDREEA-AEYQLLVEANDQGRNPGPLSATATVYIEVEDENDNYPQFSEQNYVVQVPEDVG 473
Query: 123 XXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFT 182
+DRDQ G ++A+HY++L G + + + L I+ V PLDFE V ++
Sbjct: 474 LNTAVLRVQATDRDQ-GQNAAIHYSILSGNVAGQF-YLHSLSGILDVINPLDFEDVQKYS 531
Query: 183 IKLRVQDQGSPPLY-SDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPI 241
+ ++ QD G PPL S + V VLD +D P F + A + ++ G + I
Sbjct: 532 LSIKAQDGGRPPLINSSGVVSVQVLDVNDNEPIFVSSPFQATVLENVPLGYPVV----HI 587
Query: 242 SAADQDLGINAPLQYSSTGDHKQLIVVNKDTG--QVAATKQLIAELDPSVTIVLKATQVD 299
A D D G NA L Y D + G A T ++ S + ++D
Sbjct: 588 QAVDADSGENARLHYRLV-DTASTFLGGGSAGPKNPAPTPDFPFQIHNSSGWITVCAELD 646
Query: 300 NP--DRYALATLXXXXXXXXXXXXXXXXLQ----------FTQKQYSTTVSEGASPGSVL 347
+ Y+ + FTQ Y ++E A+ GS +
Sbjct: 647 REEVEHYSFGVEAVDHGSPPMSSSTSVSITVLDVNDNDPVFTQPTYELRLNEDAAVGSSV 706
Query: 348 LTLTTVPQNTEFRESPLQFYVSDRSFLDKFAINN---AGEVILRRSLDYETTSNYFYQVM 404
LTL ++ S + + ++ + ++FA+++ G + L LDY+ Y V
Sbjct: 707 LTLQARDRDA---NSVITYQLTGGNTRNRFALSSQRGGGLITLALPLDYKQEQQYVLAVT 763
Query: 405 VTDSISNDTASINISVEDVNEWEPRFRHPQY 435
+D + TA + I+V D N P F+ Y
Sbjct: 764 ASDGTRSHTAHVLINVTDANTHRPVFQSSHY 794
Score = 97.9 bits (233), Expect = 1e-19
Identities = 99/418 (23%), Positives = 164/418 (39%), Gaps = 18/418 (4%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEKIG 70
+SED P+G+ I TLS N + + + IT +Q+ I P S + + LD E ++
Sbjct: 798 VSEDRPVGTSIATLSANDEDTGENARITYVIQDPVPQFRIDPDSGTMYTMMELDYENQVA 857
Query: 71 PSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXX 130
+ + + S + + + D NDNAPQ+ Y + E
Sbjct: 858 YT---LTIMAQDNGIPQKSDTTTLEILILDANDNAPQFLWDFYQGSIFEDAPPSTSILQV 914
Query: 131 XXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQ 190
+DRD GP+ L Y G + + +I ++ LD E V + + D+
Sbjct: 915 SATDRDS-GPNGRLLYTFQGGDDGDGDFYIEPTSGVIRTQRRLDRENVAVYNLWALAVDR 973
Query: 191 GSP-PLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLG 249
GSP PL + +QVT+LD +D P F + + ++ G+ + I A D D G
Sbjct: 974 GSPTPLSASVEIQVTILDINDNAPMFEKDELELFVEENNPVGSVV----AKIRANDPDEG 1029
Query: 250 INAPLQYSST-GDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALAT 308
NA + Y GD + ++ G + A +L E+ +V++AT R AT
Sbjct: 1030 PNAQIMYQIVEGDMRHFFQLDLLNGDLRAMVELDFEVRREYVLVVQATSAPLVSR---AT 1086
Query: 309 LXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYV 368
+ Q Y T S G + +P + L +
Sbjct: 1087 VHILLVDQNDNPPVLPDFQILFNNYVTNKSNSFPTG----VIGCIPAHDPDVSDSLNYTF 1142
Query: 369 SDRSFLDKFAINNA-GEVILRRSLDYETTSNYFYQVMVTDSISNDTASINISVEDVNE 425
+ L ++ A GE+ L R LD +V V+D I + TA + V + +
Sbjct: 1143 VQGNELRLLLLDPATGELQLSRDLDNNRPLEALMEVSVSDGIHSVTAFCTLRVTIITD 1200
Score = 97.5 bits (232), Expect = 2e-19
Identities = 108/454 (23%), Positives = 178/454 (39%), Gaps = 43/454 (9%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVL---- 149
VSV+V DVNDN P + +P+ V E D D G ++ LHY ++
Sbjct: 551 VSVQVLDVNDNEPIFVSSPFQATVLENVPLGYPVVHIQAVDADS-GENARLHYRLVDTAS 609
Query: 150 ------------PGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYS 197
P P ++ + I V LD E V +++ + D GSPP+ S
Sbjct: 610 TFLGGGSAGPKNPAPTPDFPFQIHNSSGWITVCAELDREEVEHYSFGVEAVDHGSPPMSS 669
Query: 198 DTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYS 257
T++ +TVLD +D +P FT Y L +DA G+ + T + A D+D N+ + Y
Sbjct: 670 STSVSITVLDVNDNDPVFTQPTYELRLNEDAAVGSSVLT----LQARDRD--ANSVITYQ 723
Query: 258 STGDH-KQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXX 316
TG + + ++ G T L + VL T D + L
Sbjct: 724 LTGGNTRNRFALSSQRGGGLITLALPLDYKQEQQYVLAVTASDGTRSHTAHVLINVTDAN 783
Query: 317 XXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDK 376
F Y+ +VSE G+ + TL+ ++T + + + + D + +
Sbjct: 784 THRPV------FQSSHYTVSVSEDRPVGTSIATLSANDEDTG-ENARITYVIQDP--VPQ 834
Query: 377 FAIN-NAGEVILRRSLDYETTSNYFYQVMVTDS---ISNDTASINISVEDVNEWEPRFRH 432
F I+ ++G + LDYE Y +M D+ +DT ++ I + D N+ P+F
Sbjct: 835 FRIDPDSGTMYTMMELDYENQVAYTLTIMAQDNGIPQKSDTTTLEILILDANDNAPQF-- 892
Query: 433 PQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGDAGTLALSLAG--QHARMFYINASGDLFL 490
++F G G L + G FYI + +
Sbjct: 893 -LWDFYQGSIFEDAPPSTSILQVSATDRDSGPNGRLLYTFQGGDDGDGDFYIEPTSGVIR 951
Query: 491 REEAIGNLNSSSLHLVATAIDSGIP-PRQTSVPV 523
+ + N + +L A A+D G P P SV +
Sbjct: 952 TQRRLDRENVAVYNLWALAVDRGSPTPLSASVEI 985
Score = 77.4 bits (182), Expect = 2e-13
Identities = 88/386 (22%), Positives = 151/386 (39%), Gaps = 25/386 (6%)
Query: 57 LTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVR 116
+T+ LDREE + V + S VS+ V DVNDN P + Y +R
Sbjct: 639 ITVCAELDREEV---EHYSFGVEAVDHGSPPMSSSTSVSITVLDVNDNDPVFTQPTYELR 695
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENEL-EPIIVVKKPLDF 175
++E DRD +S + Y + G ++ +I + PLD+
Sbjct: 696 LNEDAAVGSSVLTLQARDRD---ANSVITYQLTGGNTRNRFALSSQRGGGLITLALPLDY 752
Query: 176 ETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLT 235
+ + + + D G+ + + VT DA+ P F HYT + +D GT +
Sbjct: 753 KQEQQYVLAVTASD-GTRSHTAHVLINVT--DANTHRPVFQSSHYTVSVSEDRPVGTSIA 809
Query: 236 TSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKA 295
T +SA D+D G NA + Y D ++ D+G + +L E + T+ + A
Sbjct: 810 T----LSANDEDTGENARITY-VIQDPVPQFRIDPDSGTMYTMMELDYENQVAYTLTIMA 864
Query: 296 TQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQ 355
P + TL QF Y ++ E A P + +L ++ +
Sbjct: 865 QDNGIPQKSDTTTLEILILDANDNAP-----QFLWDFYQGSIFEDAPPSTSILQVSATDR 919
Query: 356 NTEFRESPL-QFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSIS---- 410
++ L F D D + +G + +R LD E + Y + D S
Sbjct: 920 DSGPNGRLLYTFQGGDDGDGDFYIEPTSGVIRTQRRLDRENVAVYNLWALAVDRGSPTPL 979
Query: 411 NDTASINISVEDVNEWEPRFRHPQYE 436
+ + I +++ D+N+ P F + E
Sbjct: 980 SASVEIQVTILDINDNAPMFEKDELE 1005
Score = 75.4 bits (177), Expect = 9e-13
Identities = 59/197 (29%), Positives = 91/197 (46%), Gaps = 12/197 (6%)
Query: 63 LDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXX 122
LDRE K + V+ T S ++V V D ND++P +E + Y RV E
Sbjct: 311 LDRETK---ETHVLRVKAVDYSTPPRSATTYITVLVKDTNDHSPVFEQSEYRERVRENLE 367
Query: 123 XXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFT 182
SDRD P ++ L Y VL G + NE ++ + LD E +
Sbjct: 368 VGYEVLTIRASDRDSP-INANLRYRVLGGAWDVFQ--LNESSGVVSTRAVLDREEAAEYQ 424
Query: 183 IKLRVQDQG-SP-PLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGP 240
+ + DQG +P PL + T+ + V D +D P+F+ ++Y +P+D L T+
Sbjct: 425 LLVEANDQGRNPGPLSATATVYIEVEDENDNYPQFSEQNYVVQVPEDVG----LNTAVLR 480
Query: 241 ISAADQDLGINAPLQYS 257
+ A D+D G NA + YS
Sbjct: 481 VQATDRDQGQNAAIHYS 497
Score = 66.5 bits (155), Expect = 4e-10
Identities = 61/265 (23%), Positives = 117/265 (44%), Gaps = 17/265 (6%)
Query: 173 LDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGT 232
LD ET ++++ D +PP + T + V V D +D +P F Y + ++ E G
Sbjct: 311 LDRETKETHVLRVKAVDYSTPPRSATTYITVLVKDTNDHSPVFEQSEYRERVRENLEVGY 370
Query: 233 FLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIV 292
+ T I A+D+D INA L+Y G + +N+ +G V+ L E ++
Sbjct: 371 EVLT----IRASDRDSPINANLRYRVLGGAWDVFQLNESSGVVSTRAVLDREEAAEYQLL 426
Query: 293 LKAT-QVDNPDRY-ALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTL 350
++A Q NP A AT+ QF+++ Y V E + +L +
Sbjct: 427 VEANDQGRNPGPLSATATVYIEVEDENDNYP-----QFSEQNYVVQVPEDVGLNTAVLRV 481
Query: 351 TTVPQNTEFRESPLQFYVSDRSFLDKFAINN-AGEVILRRSLDYETTSNYFYQVMVTDS- 408
++ + + + + + + + +F +++ +G + + LD+E Y + D
Sbjct: 482 QATDRD-QGQNAAIHYSILSGNVAGQFYLHSLSGILDVINPLDFEDVQKYSLSIKAQDGG 540
Query: 409 ---ISNDTASINISVEDVNEWEPRF 430
+ N + +++ V DVN+ EP F
Sbjct: 541 RPPLINSSGVVSVQVLDVNDNEPIF 565
Score = 40.3 bits (90), Expect = 0.030
Identities = 48/228 (21%), Positives = 87/228 (38%), Gaps = 13/228 (5%)
Query: 214 KFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTG 273
KF +Y L ++ GT + + ++ ++ ++ + ++ TG
Sbjct: 244 KFPMPNYQVALFENEPAGTLILQLHAHYTIEGEEERVSYYMEGLFDERSRGYFRIDSATG 303
Query: 274 QVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQY 333
V+ L E + + +KA P R A + F Q +Y
Sbjct: 304 AVSTDSVLDRETKETHVLRVKAVDYSTPPRSATTYITVLVKDTNDHSPV-----FEQSEY 358
Query: 334 STTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRS-LD 392
V E G +LT+ +++ + L++ V ++ D F +N + V+ R+ LD
Sbjct: 359 RERVRENLEVGYEVLTIRASDRDSPINAN-LRYRVLGGAW-DVFQLNESSGVVSTRAVLD 416
Query: 393 YETTSNYFYQVMVTDSISND-----TASINISVEDVNEWEPRFRHPQY 435
E + Y V D N TA++ I VED N+ P+F Y
Sbjct: 417 REEAAEYQLLVEANDQGRNPGPLSATATVYIEVEDENDNYPQFSEQNY 464
>AF231024-1|AAF61930.1| 3014|Homo sapiens protocadherin Flamingo 2
protein.
Length = 3014
Score = 107 bits (258), Expect = 1e-22
Identities = 102/391 (26%), Positives = 160/391 (40%), Gaps = 29/391 (7%)
Query: 63 LDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXX 122
LDREE + V R S V + V D NDN PQ+ Y V+V E
Sbjct: 415 LDREEA-AEYQLLVEANDQGRNPGPLSATATVYIEVEDENDNYPQFSEQNYVVQVPEDVG 473
Query: 123 XXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFT 182
+DRDQ G ++A+HY++L G + + + L I+ V PLDFE V ++
Sbjct: 474 LNTAVLRVQATDRDQ-GQNAAIHYSILSGNVAGQF-YLHSLSGILDVINPLDFEDVQKYS 531
Query: 183 IKLRVQDQGSPPLY-SDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPI 241
+ ++ QD G PPL S + V VLD +D P F + A + ++ G + I
Sbjct: 532 LSIKAQDGGRPPLINSSGVVSVQVLDVNDNEPIFVSSPFQATVLENVPLGYPVV----HI 587
Query: 242 SAADQDLGINAPLQYSSTGDHKQLIVVNKDTG--QVAATKQLIAELDPSVTIVLKATQVD 299
A D D G NA L Y D + G A T ++ S + ++D
Sbjct: 588 QAVDADSGENARLHYRLV-DTASTFLGGGSAGPKNPAPTPDFPFQIHNSSGWITVCAELD 646
Query: 300 NP--DRYALATLXXXXXXXXXXXXXXXXLQ----------FTQKQYSTTVSEGASPGSVL 347
+ Y+ + FTQ Y ++E A+ GS +
Sbjct: 647 REEVEHYSFGVEAVDHGSPPMSSSTSVSITVLDVNDNDPVFTQPTYELRLNEDAAVGSSV 706
Query: 348 LTLTTVPQNTEFRESPLQFYVSDRSFLDKFAINN---AGEVILRRSLDYETTSNYFYQVM 404
LTL ++ S + + ++ + ++FA+++ G + L LDY+ Y V
Sbjct: 707 LTLQARDRDA---NSVITYQLTGGNTRNRFALSSQRGGGLITLALPLDYKQEQQYVLAVT 763
Query: 405 VTDSISNDTASINISVEDVNEWEPRFRHPQY 435
+D + TA + I+V D N P F+ Y
Sbjct: 764 ASDGTRSHTAHVLINVTDANTHRPVFQSSHY 794
Score = 97.9 bits (233), Expect = 1e-19
Identities = 99/418 (23%), Positives = 164/418 (39%), Gaps = 18/418 (4%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEKIG 70
+SED P+G+ I TLS N + + + IT +Q+ I P S + + LD E ++
Sbjct: 798 VSEDRPVGTSIATLSANDEDTGENARITYVIQDPVPQFRIDPDSGTMYTMMELDYENQVA 857
Query: 71 PSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXX 130
+ + + S + + + D NDNAPQ+ Y + E
Sbjct: 858 YT---LTIMAQDNGIPQKSDTTTLEILILDANDNAPQFLWDFYQGSIFEDAPPSTSILQV 914
Query: 131 XXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQ 190
+DRD GP+ L Y G + + +I ++ LD E V + + D+
Sbjct: 915 SATDRDS-GPNGRLLYTFQGGDDGDGDFYIEPTSGVIRTQRRLDRENVAVYNLWALAVDR 973
Query: 191 GSP-PLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLG 249
GSP PL + +QVT+LD +D P F + + ++ G+ + I A D D G
Sbjct: 974 GSPTPLSASVEIQVTILDINDNAPMFEKDELELFVEENNPVGSVV----AKIRANDPDEG 1029
Query: 250 INAPLQYSST-GDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALAT 308
NA + Y GD + ++ G + A +L E+ +V++AT R AT
Sbjct: 1030 PNAQIMYQIVEGDMRHFFQLDLLNGDLRAMVELDFEVRREYVLVVQATSAPLVSR---AT 1086
Query: 309 LXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYV 368
+ Q Y T S G + +P + L +
Sbjct: 1087 VHILLVDQNDNPPVLPDFQILFNNYVTNKSNSFPTG----VIGCIPAHDPDVSDSLNYTF 1142
Query: 369 SDRSFLDKFAINNA-GEVILRRSLDYETTSNYFYQVMVTDSISNDTASINISVEDVNE 425
+ L ++ A GE+ L R LD +V V+D I + TA + V + +
Sbjct: 1143 VQGNELRLLLLDPATGELQLSRDLDNNRPLEALMEVSVSDGIHSVTAFCTLRVTIITD 1200
Score = 97.5 bits (232), Expect = 2e-19
Identities = 108/454 (23%), Positives = 178/454 (39%), Gaps = 43/454 (9%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVL---- 149
VSV+V DVNDN P + +P+ V E D D G ++ LHY ++
Sbjct: 551 VSVQVLDVNDNEPIFVSSPFQATVLENVPLGYPVVHIQAVDADS-GENARLHYRLVDTAS 609
Query: 150 ------------PGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYS 197
P P ++ + I V LD E V +++ + D GSPP+ S
Sbjct: 610 TFLGGGSAGPKNPAPTPDFPFQIHNSSGWITVCAELDREEVEHYSFGVEAVDHGSPPMSS 669
Query: 198 DTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYS 257
T++ +TVLD +D +P FT Y L +DA G+ + T + A D+D N+ + Y
Sbjct: 670 STSVSITVLDVNDNDPVFTQPTYELRLNEDAAVGSSVLT----LQARDRD--ANSVITYQ 723
Query: 258 STGDH-KQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXX 316
TG + + ++ G T L + VL T D + L
Sbjct: 724 LTGGNTRNRFALSSQRGGGLITLALPLDYKQEQQYVLAVTASDGTRSHTAHVLINVTDAN 783
Query: 317 XXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDK 376
F Y+ +VSE G+ + TL+ ++T + + + + D + +
Sbjct: 784 THRPV------FQSSHYTVSVSEDRPVGTSIATLSANDEDTG-ENARITYVIQDP--VPQ 834
Query: 377 FAIN-NAGEVILRRSLDYETTSNYFYQVMVTDS---ISNDTASINISVEDVNEWEPRFRH 432
F I+ ++G + LDYE Y +M D+ +DT ++ I + D N+ P+F
Sbjct: 835 FRIDPDSGTMYTMMELDYENQVAYTLTIMAQDNGIPQKSDTTTLEILILDANDNAPQF-- 892
Query: 433 PQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGDAGTLALSLAG--QHARMFYINASGDLFL 490
++F G G L + G FYI + +
Sbjct: 893 -LWDFYQGSIFEDAPPSTSILQVSATDRDSGPNGRLLYTFQGGDDGDGDFYIEPTSGVIR 951
Query: 491 REEAIGNLNSSSLHLVATAIDSGIP-PRQTSVPV 523
+ + N + +L A A+D G P P SV +
Sbjct: 952 TQRRLDRENVAVYNLWALAVDRGSPTPLSASVEI 985
Score = 77.4 bits (182), Expect = 2e-13
Identities = 88/386 (22%), Positives = 151/386 (39%), Gaps = 25/386 (6%)
Query: 57 LTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVR 116
+T+ LDREE + V + S VS+ V DVNDN P + Y +R
Sbjct: 639 ITVCAELDREEV---EHYSFGVEAVDHGSPPMSSSTSVSITVLDVNDNDPVFTQPTYELR 695
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENEL-EPIIVVKKPLDF 175
++E DRD +S + Y + G ++ +I + PLD+
Sbjct: 696 LNEDAAVGSSVLTLQARDRD---ANSVITYQLTGGNTRNRFALSSQRGGGLITLALPLDY 752
Query: 176 ETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLT 235
+ + + + D G+ + + VT DA+ P F HYT + +D GT +
Sbjct: 753 KQEQQYVLAVTASD-GTRSHTAHVLINVT--DANTHRPVFQSSHYTVSVSEDRPVGTSIA 809
Query: 236 TSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKA 295
T +SA D+D G NA + Y D ++ D+G + +L E + T+ + A
Sbjct: 810 T----LSANDEDTGENARITY-VIQDPVPQFRIDPDSGTMYTMMELDYENQVAYTLTIMA 864
Query: 296 TQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQ 355
P + TL QF Y ++ E A P + +L ++ +
Sbjct: 865 QDNGIPQKSDTTTLEILILDANDNAP-----QFLWDFYQGSIFEDAPPSTSILQVSATDR 919
Query: 356 NTEFRESPL-QFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSIS---- 410
++ L F D D + +G + +R LD E + Y + D S
Sbjct: 920 DSGPNGRLLYTFQGGDDGDGDFYIEPTSGVIRTQRRLDRENVAVYNLWALAVDRGSPTPL 979
Query: 411 NDTASINISVEDVNEWEPRFRHPQYE 436
+ + I +++ D+N+ P F + E
Sbjct: 980 SASVEIQVTILDINDNAPMFEKDELE 1005
Score = 75.4 bits (177), Expect = 9e-13
Identities = 59/197 (29%), Positives = 91/197 (46%), Gaps = 12/197 (6%)
Query: 63 LDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXX 122
LDRE K + V+ T S ++V V D ND++P +E + Y RV E
Sbjct: 311 LDRETK---ETHVLRVKAVDYSTPPRSATTYITVLVKDTNDHSPVFEQSEYRERVRENLE 367
Query: 123 XXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFT 182
SDRD P ++ L Y VL G + NE ++ + LD E +
Sbjct: 368 VGYEVLTIRASDRDSP-INANLRYRVLGGAWDVFQ--LNESSGVVSTRAVLDREEAAEYQ 424
Query: 183 IKLRVQDQG-SP-PLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGP 240
+ + DQG +P PL + T+ + V D +D P+F+ ++Y +P+D L T+
Sbjct: 425 LLVEANDQGRNPGPLSATATVYIEVEDENDNYPQFSEQNYVVQVPEDVG----LNTAVLR 480
Query: 241 ISAADQDLGINAPLQYS 257
+ A D+D G NA + YS
Sbjct: 481 VQATDRDQGQNAAIHYS 497
Score = 66.5 bits (155), Expect = 4e-10
Identities = 61/265 (23%), Positives = 117/265 (44%), Gaps = 17/265 (6%)
Query: 173 LDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGT 232
LD ET ++++ D +PP + T + V V D +D +P F Y + ++ E G
Sbjct: 311 LDRETKETHVLRVKAVDYSTPPRSATTYITVLVKDTNDHSPVFEQSEYRERVRENLEVGY 370
Query: 233 FLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIV 292
+ T I A+D+D INA L+Y G + +N+ +G V+ L E ++
Sbjct: 371 EVLT----IRASDRDSPINANLRYRVLGGAWDVFQLNESSGVVSTRAVLDREEAAEYQLL 426
Query: 293 LKAT-QVDNPDRY-ALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTL 350
++A Q NP A AT+ QF+++ Y V E + +L +
Sbjct: 427 VEANDQGRNPGPLSATATVYIEVEDENDNYP-----QFSEQNYVVQVPEDVGLNTAVLRV 481
Query: 351 TTVPQNTEFRESPLQFYVSDRSFLDKFAINN-AGEVILRRSLDYETTSNYFYQVMVTDS- 408
++ + + + + + + + +F +++ +G + + LD+E Y + D
Sbjct: 482 QATDRD-QGQNAAIHYSILSGNVAGQFYLHSLSGILDVINPLDFEDVQKYSLSIKAQDGG 540
Query: 409 ---ISNDTASINISVEDVNEWEPRF 430
+ N + +++ V DVN+ EP F
Sbjct: 541 RPPLINSSGVVSVQVLDVNDNEPIF 565
Score = 40.3 bits (90), Expect = 0.030
Identities = 48/228 (21%), Positives = 87/228 (38%), Gaps = 13/228 (5%)
Query: 214 KFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTG 273
KF +Y L ++ GT + + ++ ++ ++ + ++ TG
Sbjct: 244 KFPMPNYQVALFENEPAGTLILQLHAHYTIEGEEERVSYYMEGLFDERSRGYFRIDSATG 303
Query: 274 QVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQY 333
V+ L E + + +KA P R A + F Q +Y
Sbjct: 304 AVSTDSVLDRETKETHVLRVKAVDYSTPPRSATTYITVLVKDTNDHSPV-----FEQSEY 358
Query: 334 STTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRS-LD 392
V E G +LT+ +++ + L++ V ++ D F +N + V+ R+ LD
Sbjct: 359 RERVRENLEVGYEVLTIRASDRDSPINAN-LRYRVLGGAW-DVFQLNESSGVVSTRAVLD 416
Query: 393 YETTSNYFYQVMVTDSISND-----TASINISVEDVNEWEPRFRHPQY 435
E + Y V D N TA++ I VED N+ P+F Y
Sbjct: 417 REEAAEYQLLVEANDQGRNPGPLSATATVYIEVEDENDNYPQFSEQNY 464
>AY354497-1|AAR10443.1| 2916|Homo sapiens cadherin protein protein.
Length = 2916
Score = 107 bits (257), Expect = 2e-22
Identities = 108/438 (24%), Positives = 179/438 (40%), Gaps = 29/438 (6%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGD-ITLRLQEKGAAVG---IVPGSKNLTLLRALDRE 66
+ E+ PIG+++ + D L I ++ I P L + LDRE
Sbjct: 1064 VEENVPIGTLVYVFNAKDDDGSFLNSRIQYYIESHNPGTNPFLIHPSFGTLVTVSRLDRE 1123
Query: 67 EKIGPSNVYVNVRCDRR-RTTDPSF-VIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXX 124
P+ + D+ TD + + + DVND+ P + P A V E
Sbjct: 1124 SI--PTVILTVTASDQAVNVTDRRLRSLTAQIVILDVNDHNPTFISFPNA-HVKEDVTVG 1180
Query: 125 XXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFE-NELEPIIVVKKPLDFETVNNFTI 183
D D+ G + + Y++L G +E + F +E ++ PLD+E +
Sbjct: 1181 SLVHHITAHDPDE-GRNGKVTYSILSG--NENMTFMLDESSGLLTTTCPLDYEMKTQHIL 1237
Query: 184 KLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISA 243
+ D G+P L S TL VTVLD +D+ P F Y A + ++ G F+T + A
Sbjct: 1238 TVLALDDGTPALSSSQTLTVTVLDVNDEAPVFKQHLYEASVKENQNPGEFVTR----VEA 1293
Query: 244 ADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPD 302
D+D G+N+ LQ+ G +L +N DTG+V T L E+ T+ + P
Sbjct: 1294 LDRDSGVNSKLQFEIMPGASFELFEINSDTGEVVTTTILDREIQEVFTLRVLVRDGGFPS 1353
Query: 303 RYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRES 362
+ T+ +F Y V E P V L + R
Sbjct: 1354 LSSTTTILCTVEDENDHAP-----EFIVSSYDIEVLENQEPEVVYTVLASDMDAGNNR-- 1406
Query: 363 PLQFYVSDRSFLDKFAINN-AGEVILRRSLDYETTSNYFYQVMVTDSISNDTASI---NI 418
+++++ D + + F IN +GE+ R+LD E SN+ ++ +D +S+ +
Sbjct: 1407 AVEYHIIDGNTDECFTINEMSGELSTTRALDREQISNFTLVILCSDLGDPPRSSVIHLQV 1466
Query: 419 SVEDVNEWEPRFRHPQYE 436
V D N+ P F Y+
Sbjct: 1467 RVLDANDHSPSFPTLYYQ 1484
Score = 89.8 bits (213), Expect = 4e-17
Identities = 87/356 (24%), Positives = 155/356 (43%), Gaps = 32/356 (8%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
+ V+V D+NDNAP + + AV ++E D D +A P
Sbjct: 1878 IKVQVTDINDNAPAFLPSE-AVEITEDSLPGVIVTHVSVHDVDLNSAF-IFSFAKESNPG 1935
Query: 154 SEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNP 213
+++ +N ++V+ K LDFE + + + +++ D Y++ L V VLD +D P
Sbjct: 1936 TKFAIDQNT--GVVVLVKTLDFEEMTEYELLIQISDSVH---YTEGALVVRVLDVNDNPP 1990
Query: 214 KFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTG 273
F+ + Y +P+ G + T +SA D L N + Y K+ + K+
Sbjct: 1991 VFSQDFYQVTVPESIPVGYSVLT----LSATD--LESNENISYRILSSSKEFSIDPKNGT 2044
Query: 274 QVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQY 333
+ L+ + + +++A+ NPD AL + +FT K Y
Sbjct: 2045 IFTISPVLLLDTISTTQFLVEASDGGNPDLRALTLVEIGIEDMNNYAP-----EFTVKSY 2099
Query: 334 STTVSEGASPGSVLLTLTTVP-----QNTEFRESPLQ------FYVSDRSFLDKFAINNA 382
+ ++SE A GS L+T + + +NT S + F+V + F ++
Sbjct: 2100 NLSLSEDALVGSTLVTFSNIDHDWTRENTYVEYSIISGNSQNNFHVETKFFHSEYPYKQV 2159
Query: 383 GEVILRRSLDYETTSNYFYQVMVTDS---ISNDTASINISVEDVNEWEPRFRHPQY 435
G ++L SLD E ++++ ++ +DS + TA I+I V DVN+ P F Y
Sbjct: 2160 GYLVLLHSLDREASASHELVILASDSGCPPLSSTAVISIQVLDVNDNPPNFSSLSY 2215
Score = 83.8 bits (198), Expect = 2e-15
Identities = 57/187 (30%), Positives = 90/187 (48%), Gaps = 7/187 (3%)
Query: 98 VWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYL 157
V D ND+AP++ + Y + V E SD D G + A+ Y ++ G E
Sbjct: 1364 VEDENDHAPEFIVSSYDIEVLENQEPEVVYTVLA-SDMDA-GNNRAVEYHIIDGNTDECF 1421
Query: 158 GFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTY 217
NE+ + + LD E ++NFT+ + D G PP S LQV VLDA+D +P F
Sbjct: 1422 TI-NEMSGELSTTRALDREQISNFTLVILCSDLGDPPRSSVIHLQVRVLDANDHSPSFPT 1480
Query: 218 EHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAA 277
+Y + + +DAE GT + +SA D+D G+N +Y T + ++ +G +
Sbjct: 1481 LYYQSSVREDAEVGTVVLV----LSAVDKDEGLNGQTEYFLTDEASGAFTIDPMSGTLKT 1536
Query: 278 TKQLIAE 284
+ L E
Sbjct: 1537 SNTLDRE 1543
Score = 81.0 bits (191), Expect = 2e-14
Identities = 100/451 (22%), Positives = 181/451 (40%), Gaps = 43/451 (9%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEKIG 70
+ E P+G + TLS S + +I+ R+ I P + + + + + I
Sbjct: 2001 VPESIPVGYSVLTLSATDLESNE--NISYRILSSSKEFSIDPKNGTIFTISPVLLLDTI- 2057
Query: 71 PSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXX 130
S V D + V + + D+N+ AP++ Y + +SE
Sbjct: 2058 -STTQFLVEASDGGNPDLRALTLVEIGIEDMNNYAPEFTVKSYNLSLSEDALVGSTLVTF 2116
Query: 131 XXSDRDQPGPHSALHYAVLPGP-----HSEYLGFENELE----PIIVVKKPLDFETVNNF 181
D D ++ + Y+++ G H E F +E +V+ LD E +
Sbjct: 2117 SNIDHDWTRENTYVEYSIISGNSQNNFHVETKFFHSEYPYKQVGYLVLLHSLDREASASH 2176
Query: 182 TIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPI 241
+ + D G PPL S + + VLD +D P F+ Y + + G+ +T +
Sbjct: 2177 ELVILASDSGCPPLSSTAVISIQVLDVNDNPPNFSSLSYHTHVKESTPLGSHITV----V 2232
Query: 242 SAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDN 300
SA D+D G +A + Y+ +G+ K + ++TG + K L E T+ ++A+ +
Sbjct: 2233 SANDRDTGSHAEIIYNIISGNEKGHFYLEENTGVLYLIKPLDYEKMTKFTLTVQASDAEK 2292
Query: 301 PDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFR 360
++ A + QF +S V E S + ++ + +F
Sbjct: 2293 -KHFSFAVVFVSVLDDNDHAP-----QFMFSSFSCIVPENLPISSTICSINAL----DFD 2342
Query: 361 ESP---LQFYVSDRSFL--------DKFAINN-AGEVILRRSLDYETTSNYFYQVMVTDS 408
P L + + FL D F I+ G++ ++ LDYE + Y V D
Sbjct: 2343 AGPYGELTYSIVSPCFLTHGMSYDHDLFLIDPLTGDIHAKQILDYENGNKYCLTVQAKDK 2402
Query: 409 ISNDTAS--INISVEDVNEWEPRFRHPQYEF 437
+ TAS + + +E ++E+EP F QY F
Sbjct: 2403 -GDATASLVVWVDIEGIDEFEPIFTQDQYFF 2432
Score = 79.0 bits (186), Expect = 7e-14
Identities = 103/458 (22%), Positives = 175/458 (38%), Gaps = 34/458 (7%)
Query: 78 VRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQ 137
+ D + S + +S+ V D ND++P ++ + V E D D
Sbjct: 1025 ITTDHSKNLSLSSTVFLSIDVEDQNDHSPSFQDELIVISVEENVPIGTLVYVFNAKDDDG 1084
Query: 138 PGPHSALHYAVLP-GPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQG---SP 193
+S + Y + P + ++ V + LD E++ + + DQ +
Sbjct: 1085 SFLNSRIQYYIESHNPGTNPFLIHPSFGTLVTVSR-LDRESIPTVILTVTASDQAVNVTD 1143
Query: 194 PLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAP 253
T Q+ +LD +D NP F A + +D G+ + I+A D D G N
Sbjct: 1144 RRLRSLTAQIVILDVNDHNPTFI-SFPNAHVKEDVTVGSLVHH----ITAHDPDEGRNGK 1198
Query: 254 LQYSS-TGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXX 312
+ YS +G+ ++++ +G + T L E+ + + A P + TL
Sbjct: 1199 VTYSILSGNENMTFMLDESSGLLTTTCPLDYEMKTQHILTVLALDDGTPALSSSQTLTVT 1258
Query: 313 XXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRS 372
F Q Y +V E +PG + + + +++ S LQF + +
Sbjct: 1259 VLDVNDEAPV-----FKQHLYEASVKENQNPGEFVTRVEALDRDSGVN-SKLQFEIMPGA 1312
Query: 373 FLDKFAINN-AGEVILRRSLDYETTSNYFYQVMVTD----SISNDTASINISVEDVNEWE 427
+ F IN+ GEV+ LD E + +V+V D S+S+ T +I +VED N+
Sbjct: 1313 SFELFEINSDTGEVVTTTILDREIQEVFTLRVLVRDGGFPSLSS-TTTILCTVEDENDHA 1371
Query: 428 PRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGDAG-TLALS---LAGQHARMFYIN 483
P F Y+ E +A D DAG A+ + G F IN
Sbjct: 1372 PEFIVSSYDIE-------VLENQEPEVVYTVLASDMDAGNNRAVEYHIIDGNTDECFTIN 1424
Query: 484 ASGDLFLREEAIGNLNSSSLHLVATAIDSGIPPRQTSV 521
A+ S+ LV D G PPR + +
Sbjct: 1425 EMSGELSTTRALDREQISNFTLVILCSDLGDPPRSSVI 1462
Score = 77.8 bits (183), Expect = 2e-13
Identities = 82/347 (23%), Positives = 145/347 (41%), Gaps = 25/347 (7%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
V+V + D NDN+P +E + Y VSE+ +D D G + + Y++L G
Sbjct: 1773 VAVLIQDENDNSPCFEQSIYQASVSESQLYNAHVIQVFATDLDS-GLNGLIEYSILSGNQ 1831
Query: 154 SEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNP 213
E + L +I K LD+E +++++ ++ D+G P L + T ++V V D +D P
Sbjct: 1832 EEAFQID-ALSGVITTKAILDYELTSSYSLIVQATDKGMPRLSNTTVIKVQVTDINDNAP 1890
Query: 214 KFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTG 273
F + +D+ G +T +S D DL ++ + ++++TG
Sbjct: 1891 AFLPSE-AVEITEDSLPGVIVT----HVSVHDVDLNSAFIFSFAKESNPGTKFAIDQNTG 1945
Query: 274 QVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQY 333
V K L E +++ Q+ + Y L F+Q Y
Sbjct: 1946 VVVLVKTLDFEEMTEYELLI---QISDSVHYTEGALVVRVLDVNDNPPV-----FSQDFY 1997
Query: 334 STTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRS--L 391
TV E G +LTL+ + E E+ + + + S +F+I+ I S L
Sbjct: 1998 QVTVPESIPVGYSVLTLSAT--DLESNEN-ISYRILSSS--KEFSIDPKNGTIFTISPVL 2052
Query: 392 DYETTSNYFYQVMVTDSISNDTAS---INISVEDVNEWEPRFRHPQY 435
+T S + V +D + D + + I +ED+N + P F Y
Sbjct: 2053 LLDTISTTQFLVEASDGGNPDLRALTLVEIGIEDMNNYAPEFTVKSY 2099
Score = 77.0 bits (181), Expect = 3e-13
Identities = 72/272 (26%), Positives = 109/272 (40%), Gaps = 16/272 (5%)
Query: 167 IVVKKPLDFETVNNFTIKLRVQDQ-GSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLP 225
I +KPLD ET + L VQ Q GS P S T + +TV+D +D +P F +
Sbjct: 433 IRTRKPLDHETQP--VVVLTVQAQLGSAPACSSTEVNITVMDVNDNHPAFLRTSDEIRIS 490
Query: 226 DDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLIAEL 285
GT L + A D+D G N ++YS + +++ G + L A
Sbjct: 491 QTTPPGTALYLA----RAEDRDSGRNGLIRYSIASPQPGVFAIDRALGVLFLNGSLGAGE 546
Query: 286 DPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGS 345
+T+ L+A + AL L F Y VSE SP +
Sbjct: 547 QRELTLTLRAEDQGVHPQAALLVLTVVIEKREHSPSWT----FEHLVYQVEVSESLSPMT 602
Query: 346 VLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAINN-AGEVILRRSLDYETTSNYFYQVM 404
+L P + SPL++ + F I G + LRR DYE+T Y ++V
Sbjct: 603 QMLQTQAHPLGPQRAASPLRYSLEPSVDSAMFGIRPYTGWIYLRRQFDYESTQTYNFRVF 662
Query: 405 V----TDSISNDTASINISVEDVNEWEPRFRH 432
+ N + ++ + V D N+ P F H
Sbjct: 663 AWIPEDGFLQNVSTTVIVRVWDENDNSPTFLH 694
Score = 73.3 bits (172), Expect = 3e-12
Identities = 66/265 (24%), Positives = 109/265 (41%), Gaps = 11/265 (4%)
Query: 173 LDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGT 232
LD E + + + V D+GSPP + + V+V D +D P F L EG
Sbjct: 797 LDREHRGHHEMTVLVTDRGSPPRNATMAVYVSVTDINDNRPFFPQCLPGKELHVKVLEGQ 856
Query: 233 FLTTSPGPISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTI 291
+ + A D D G NA + YS S+ D ++ + G++ T L + PS +
Sbjct: 857 PVNMLVTTVFAKDPDEGNNAEVTYSVSSEDSSDHFKIDANNGEIRTTTILSYDYRPSYRM 916
Query: 292 VLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLT 351
+ AT P A + +Q + E P ++ +
Sbjct: 917 SVIATDQGVPPLQGQAVVNIQVIPLSKGRAI-----MSQNIRHLIIPENLKPTKIMSLIK 971
Query: 352 TVPQNTEFRESPLQFYVSDRSFLDKFAINNA-GEVILRRSLDYETTSNYFYQVMVTDSIS 410
+ + L F + F I+++ G++ L + LDYETTS+Y ++V+ TD
Sbjct: 972 SSDHLQQHYNGKLHFSIVADDKDGHFEIDSSTGDLFLSKELDYETTSHYLFRVITTDHSK 1031
Query: 411 N----DTASINISVEDVNEWEPRFR 431
N T ++I VED N+ P F+
Sbjct: 1032 NLSLSSTVFLSIDVEDQNDHSPSFQ 1056
Score = 68.9 bits (161), Expect = 7e-11
Identities = 70/281 (24%), Positives = 125/281 (44%), Gaps = 23/281 (8%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRL---QEKGAAVGIVPGSKNLTLLRALDREE 67
+ E TP+GS I +S N + +I + EKG + + L L++ LD E+
Sbjct: 2219 VKESTPLGSHITVVSANDRDTGSHAEIIYNIISGNEKGHFY-LEENTGVLYLIKPLDYEK 2277
Query: 68 KIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXX 127
+ + V+ SF + V V V D ND+APQ+ + ++ V E
Sbjct: 2278 M---TKFTLTVQASDAEKKHFSFAV-VFVSVLDDNDHAPQFMFSSFSCIVPENLPISSTI 2333
Query: 128 XXXXXSDRDQPGPHSALHYAVL-PGPHSEYLGFENEL---EPI---IVVKKPLDFETVNN 180
D D GP+ L Y+++ P + + ++++L +P+ I K+ LD+E N
Sbjct: 2334 CSINALDFDA-GPYGELTYSIVSPCFLTHGMSYDHDLFLIDPLTGDIHAKQILDYENGNK 2392
Query: 181 FTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGP 240
+ + ++ +D+G + + V + D+ P FT + Y LP+ ++ + G
Sbjct: 2393 YCLTVQAKDKGDAT--ASLVVWVDIEGIDEFEPIFTQDQYFFTLPEKNKDRQLI----GR 2446
Query: 241 ISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQL 281
+ A+D D GI+ + Y S G VNK G + + L
Sbjct: 2447 VEASDADAGIDGVILY-SLGTSSPFFSVNKTNGNIYLIRAL 2486
Score = 63.3 bits (147), Expect = 4e-09
Identities = 63/274 (22%), Positives = 121/274 (44%), Gaps = 19/274 (6%)
Query: 167 IVVKKP--LDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALL 224
+ VK+P LDFE N + + + G + V + D +D +P F Y A
Sbjct: 1740 LTVKEPKFLDFEVRNEVQLIVLAESSGHRAYCK---VAVLIQDENDNSPCFEQSIYQA-- 1794
Query: 225 PDDAEEGTFLTTSPGPISAADQDLGINAPLQYSS-TGDHKQLIVVNKDTGQVAATKQLIA 283
E + A D D G+N ++YS +G+ ++ ++ +G + L
Sbjct: 1795 --SVSESQLYNAHVIQVFATDLDSGLNGLIEYSILSGNQEEAFQIDALSGVITTKAILDY 1852
Query: 284 ELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASP 343
EL S +++++AT P R + T+ F + + ++E + P
Sbjct: 1853 ELTSSYSLIVQATDKGMP-RLSNTTVIKVQVTDINDNAPA----FLPSE-AVEITEDSLP 1906
Query: 344 GSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQ 402
G V++T +V + + + + + + + KFAI+ N G V+L ++LD+E + Y
Sbjct: 1907 G-VIVTHVSV-HDVDLNSAFIFSFAKESNPGTKFAIDQNTGVVVLVKTLDFEEMTEYELL 1964
Query: 403 VMVTDSISNDTASINISVEDVNEWEPRFRHPQYE 436
+ ++DS+ ++ + V DVN+ P F Y+
Sbjct: 1965 IQISDSVHYTEGALVVRVLDVNDNPPVFSQDFYQ 1998
Score = 63.3 bits (147), Expect = 4e-09
Identities = 97/439 (22%), Positives = 172/439 (39%), Gaps = 35/439 (7%)
Query: 7 ESFFISEDTPIGSIIGTLSVNG-DPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDR 65
E+ I+ED+ G I+ +SV+ D + + G I + + L++ LD
Sbjct: 1896 EAVEITEDSLPGVIVTHVSVHDVDLNSAFIFSFAKESNPGTKFAIDQNTGVVVLVKTLDF 1955
Query: 66 EEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXX 125
EE + + + + D T+ + V VRV DVNDN P + Y V V E+
Sbjct: 1956 EE-MTEYELLIQIS-DSVHYTEGALV----VRVLDVNDNPPVFSQDFYQVTVPESIPVGY 2009
Query: 126 XXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKL 185
+D + + + Y +L S+ + + I + L +T++ +
Sbjct: 2010 SVLTLSATDLES---NENISYRILSS--SKEFSIDPKNGTIFTISPVLLLDTISTTQFLV 2064
Query: 186 RVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAAD 245
D G+P L + T +++ + D ++ P+FT + Y L +DA G+ L T S D
Sbjct: 2065 EASDGGNPDLRALTLVEIGIEDMNNYAPEFTVKSYNLSLSEDALVGSTLVT----FSNID 2120
Query: 246 QD-LGINAPLQYS-STGDHKQLIVVN----------KDTGQVAATKQLIAELDPSVTIVL 293
D N ++YS +G+ + V K G + L E S +V+
Sbjct: 2121 HDWTRENTYVEYSIISGNSQNNFHVETKFFHSEYPYKQVGYLVLLHSLDREASASHELVI 2180
Query: 294 KATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTV 353
A+ P + A + F+ Y T V E GS + ++
Sbjct: 2181 LASDSGCPPLSSTAVISIQVLDVNDNPP-----NFSSLSYHTHVKESTPLGSHITVVSAN 2235
Query: 354 PQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSISN-- 411
++T + +S + N G + L + LDYE + + V +D+
Sbjct: 2236 DRDTGSHAEIIYNIISGNEKGHFYLEENTGVLYLIKPLDYEKMTKFTLTVQASDAEKKHF 2295
Query: 412 DTASINISVEDVNEWEPRF 430
A + +SV D N+ P+F
Sbjct: 2296 SFAVVFVSVLDDNDHAPQF 2314
Score = 62.1 bits (144), Expect = 9e-09
Identities = 98/465 (21%), Positives = 167/465 (35%), Gaps = 24/465 (5%)
Query: 54 SKNLTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPY 113
S L+ RALDRE+ SN + + C S VI + VRV D ND++P + Y
Sbjct: 1427 SGELSTTRALDREQI---SNFTLVILCSDLGDPPRSSVIHLQVRVLDANDHSPSFPTLYY 1483
Query: 114 AVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPL 173
V E D+D+ G + Y + + + + + L
Sbjct: 1484 QSSVREDAEVGTVVLVLSAVDKDE-GLNGQTEYFLTDEASGAFT--IDPMSGTLKTSNTL 1540
Query: 174 DFETVNNFTIKLRVQDQGSPPLYSDTT-LQVTVLDADDQNPKFTYEHYTALLPDDAEEGT 232
D E + T +D S T ++V V D +D +P + L E T
Sbjct: 1541 DREARSQHTFSAVARDCSIQGSRSTTVIIKVYVTDVNDNDPVLEQNPFDVFL--SPESPT 1598
Query: 233 FLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIV 292
TT + A D DLG N + + S + + + ++K TG++ + +E P + +
Sbjct: 1599 NQTTV--IVRADDLDLGPNGTVVF-SFAETQSMFSIDKYTGEIQFQQNPSSEYFP-IWLQ 1654
Query: 293 LKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTT 352
LK T P R L + F+ Y V+E G+ ++T+
Sbjct: 1655 LKVTDQGIPARTTTGLL------VIHMEGEDVKISFSHHLYKGLVTENCEAGTSIVTVKA 1708
Query: 353 -VPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSISN 411
P + + F ++ L + + V + LD+E + V+ S
Sbjct: 1709 FAPDSIQDSMKYSIFSGNEDGVLSLCSKSGQLTVKEPKFLDFEVRNEVQLIVLAESSGHR 1768
Query: 412 DTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGDAGTLALS 471
+ + ++D N+ P F Y+ G G + S
Sbjct: 1769 AYCKVAVLIQDENDNSPCFEQSIYQ---ASVSESQLYNAHVIQVFATDLDSGLNGLIEYS 1825
Query: 472 -LAGQHARMFYINASGDLFLREEAIGNLNSSSLHLVATAIDSGIP 515
L+G F I+A + + + +SS L+ A D G+P
Sbjct: 1826 ILSGNQEEAFQIDALSGVITTKAILDYELTSSYSLIVQATDKGMP 1870
Score = 54.8 bits (126), Expect = 1e-06
Identities = 53/214 (24%), Positives = 87/214 (40%), Gaps = 11/214 (5%)
Query: 8 SFFISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQ--EKGAAVGIVPGSKNLTLLRALDR 65
+F + ED P S IGT+ +P I R+ + G I P + + LD
Sbjct: 383 TFLVYEDVPEDSPIGTVKAR-EPLNSSEPIFYRISSGDLGGKFSIHPRLGTIRTRKPLDH 441
Query: 66 EEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXX 125
E + V + V+ S V++ V DVNDN P + +R+S+T
Sbjct: 442 ETQ---PVVVLTVQAQLGSAPACSST-EVNITVMDVNDNHPAFLRTSDEIRISQTTPPGT 497
Query: 126 XXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKL 185
DRD G + + Y++ P + L ++ + L T+ L
Sbjct: 498 ALYLARAEDRDS-GRNGLIRYSI-ASPQPGVFAIDRAL-GVLFLNGSLGAGEQRELTLTL 554
Query: 186 RVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEH 219
R +DQG P + L V V++ + +P +T+EH
Sbjct: 555 RAEDQGVHPQAALLVLTV-VIEKREHSPSWTFEH 587
>BC047608-1|AAH47608.1| 794|Homo sapiens cadherin 12, type 2
(N-cadherin 2) protein.
Length = 794
Score = 106 bits (255), Expect = 3e-22
Identities = 112/453 (24%), Positives = 195/453 (43%), Gaps = 32/453 (7%)
Query: 3 GGAVESFFISEDTPIGS---IIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTL 59
G FF+ E+ +GS +G L + D E TL G I + ++
Sbjct: 55 GWVWNQFFVLEEY-VGSEPQYVGKLHSDLDKGEGTVKYTLSGDGAGTVFTIDETTGDIHA 113
Query: 60 LRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSE 119
+R+LDREEK + V + R+ +P + V+ D+NDN P++ PY V E
Sbjct: 114 IRSLDREEKPFYTLRAQAVDIETRKPLEPESEFIIKVQ--DINDNEPKFLDGPYVATVPE 171
Query: 120 TXXXXXXXXXXXXSDRDQP--GPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFET 177
+D D P G + + Y++L G Y + + I +D E
Sbjct: 172 MSPVGAYVLQVKATDADDPTYGNSARVVYSILQG--QPYFSIDPKTGVIRTALPNMDREV 229
Query: 178 VNNFTIKLRVQDQGSP--PLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLT 235
+ + ++ +D G L T + +T+ D +D P+F + +P+ + G+ +
Sbjct: 230 KEQYQVLIQAKDMGGQLGGLAGTTIVNITLTDVNDNPPRFPKSIFHLKVPESSPIGSAI- 288
Query: 236 TSPGPISAADQDLGINAPLQYSST-GDHKQL--IVVNKDT--GQVAATKQLIAELDPSVT 290
G I A D D G NA ++Y+ GD L IV ++DT G + K L E + T
Sbjct: 289 ---GRIRAVDPDFGQNAEIEYNIVPGDGGNLFDIVTDEDTQEGVIKLKKPLDFETKKAYT 345
Query: 291 IVLKATQVDNPDRY-ALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLT 349
++A+ + R+ + F++ Y+ V E G+++
Sbjct: 346 FKVEASNLHLDHRFHSAGPFKDTATVKISVLDVDEPPVFSKPLYTMEVYEDTPVGTIIGA 405
Query: 350 LTTVPQNTEFRESPLQFYVSDRSFLDK-FAIN-NAGEVILRRSLDYETTSNYFYQVMVTD 407
+T Q+ + S +++++ +S D F I+ N G + LD E+T+ Y + + +
Sbjct: 406 VTA--QDLDVGSSAVRYFIDWKSDGDSYFTIDGNEGTIATNELLDRESTAQYNFSI-IAS 462
Query: 408 SISND--TASIN--ISVEDVNEWEPRFRHPQYE 436
+SN T+ +N I+V DVNE+ P P YE
Sbjct: 463 KVSNPLLTSKVNILINVLDVNEFPPEISVP-YE 494
>L34057-1|AAA35623.1| 794|Homo sapiens cadherin-12 protein.
Length = 794
Score = 105 bits (251), Expect = 9e-22
Identities = 111/453 (24%), Positives = 194/453 (42%), Gaps = 32/453 (7%)
Query: 3 GGAVESFFISEDTPIGS---IIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTL 59
G FF+ E+ +GS +G L + D E TL G I + ++
Sbjct: 55 GWVWNQFFVLEEY-VGSEPQYVGKLHSDLDKGEGTVKYTLSGDGAGTVFTIDETTGDIHA 113
Query: 60 LRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSE 119
+R+LDREEK + V + R+ +P + V+ D+NDN P++ PY V E
Sbjct: 114 IRSLDREEKPFYTLRAQAVDIETRKPLEPESEFIIKVQ--DINDNEPKFLDGPYVATVPE 171
Query: 120 TXXXXXXXXXXXXSDRDQP--GPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFET 177
+D D P G + + Y++L G Y + + I +D E
Sbjct: 172 MSPVGAYVLQVKATDADDPTYGNSARVVYSILQG--QPYFSIDPKTGVIRTALPNMDREV 229
Query: 178 VNNFTIKLRVQDQGSP--PLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLT 235
+ + ++ +D G L T + +T+ D +D P+F + +P+ + G+ +
Sbjct: 230 KEQYQVLIQAKDMGGQLGGLAGTTIVNITLTDVNDNPPRFPKSIFHLKVPESSPIGSAI- 288
Query: 236 TSPGPISAADQDLGINAPLQYSST-GDHKQL--IVVNKDT--GQVAATKQLIAELDPSVT 290
G I A D D G NA ++Y+ GD L IV ++DT G + K L E + T
Sbjct: 289 ---GRIRAVDPDFGQNAEIEYNIVPGDGGNLFDIVTDEDTQEGVIKLKKPLDFETKKAYT 345
Query: 291 IVLKATQVDNPDRY-ALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLT 349
++A+ + R+ + F++ Y+ V E G+++
Sbjct: 346 FKVEASNLHLDHRFHSAGPFKDTATVKISVLDVDEPPVFSKPLYTMEVYEDTPVGTIIGA 405
Query: 350 LTTVPQNTEFRESPLQFYVSDRSFLDK-FAIN-NAGEVILRRSLDYETTSNYFYQVMVTD 407
+T Q+ + +++++ +S D F I+ N G + LD E+T+ Y + + +
Sbjct: 406 VTA--QDLDVGSGAVRYFIDWKSDGDSYFTIDGNEGTIATNELLDRESTAQYNFSI-IAS 462
Query: 408 SISND--TASIN--ISVEDVNEWEPRFRHPQYE 436
+SN T+ +N I+V DVNE+ P P YE
Sbjct: 463 KVSNPLLTSKVNILINVLDVNEFPPEISVP-YE 494
>L33477-1|AAB48539.1| 794|Homo sapiens Br-cadherin protein.
Length = 794
Score = 105 bits (251), Expect = 9e-22
Identities = 112/453 (24%), Positives = 194/453 (42%), Gaps = 32/453 (7%)
Query: 3 GGAVESFFISEDTPIGS---IIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTL 59
G FF+ E+ +GS +G L + D E TL G I + ++
Sbjct: 55 GWVWNQFFVLEEY-MGSEPQYVGKLHSDLDKGEGTVKYTLSGDGAGTVFTIDETTGDIHA 113
Query: 60 LRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSE 119
+R+LDREEK + V + R+ +P + V+ D+NDN P++ PY V E
Sbjct: 114 IRSLDREEKPFYTLRAQAVDIETRKPLEPESEFIIKVQ--DINDNEPKFLDGPYVATVPE 171
Query: 120 TXXXXXXXXXXXXSDRDQP--GPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFET 177
+D D P G + + Y++L G Y + + I +D E
Sbjct: 172 MSPVGAYVLQVKATDADDPTYGNSARVVYSILQG--QPYFSIDPKTGVIRTALPNMDREV 229
Query: 178 VNNFTIKLRVQDQGSP--PLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLT 235
+ + ++ +D G L T + +T+ D +D P+F + +P+ + G+ +
Sbjct: 230 KEQYQVLIQAKDMGGQLGGLAGTTIVNITLTDVNDNPPRFPKSIFHLKVPESSPIGSAI- 288
Query: 236 TSPGPISAADQDLGINAPLQYSST-GDHKQL--IVVNKDT--GQVAATKQLIAELDPSVT 290
G I A D D G NA ++Y+ GD L IV ++DT G + K L E + T
Sbjct: 289 ---GRIRAVDPDFGQNAEIEYNIVPGDGGNLFDIVTDEDTQEGVIKLKKPLDFETKKAYT 345
Query: 291 IVLKATQVDNPDRY-ALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLT 349
+ A+ + R+ + F++ Y+ V E G+++
Sbjct: 346 FKVDASNLHLDHRFHSAGPFKDTATVKISVLDVDEPPVFSKPLYTMEVYEDTPVGTIIGA 405
Query: 350 LTTVPQNTEFRESPLQFYVSDRSFLDK-FAIN-NAGEVILRRSLDYETTSNYFYQVMVTD 407
+T Q+ + S +++++ +S D F I+ N G + LD E+T+ Y + + +
Sbjct: 406 VTA--QDLDVGSSAVRYFIDWKSDGDSYFTIDGNEGTIATNELLDRESTAQYNFSI-IAS 462
Query: 408 SISND--TASIN--ISVEDVNEWEPRFRHPQYE 436
+SN T+ +N I+V DVNE+ P P YE
Sbjct: 463 KVSNPLLTSKVNILINVLDVNEFPPEISVP-YE 494
>AF152515-1|AAD43775.1| 820|Homo sapiens protocadherin gamma A8
short form protein protein.
Length = 820
Score = 104 bits (249), Expect = 2e-21
Identities = 109/441 (24%), Positives = 183/441 (41%), Gaps = 30/441 (6%)
Query: 9 FFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAA--VGIVPGSKNLTLLRALDR 65
+ + E+T GS +G +S + G L +R+ +G + P S +L +DR
Sbjct: 33 YSVPEETDKGSFVGNISKDLGLDPRKLAKHGVRIVSRGRTQLFALNPRSGSLITAGRIDR 92
Query: 66 EEKIGPS-NVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXX 124
EE S +N+ D + V + + D+NDN P+++ V+++E
Sbjct: 93 EELCAQSPRCLININT---LVEDKGKLFGVEIEIIDINDNNPKFQVEDLEVKINEIAVPG 149
Query: 125 XXXXXXXXSDRDQPGPHSALHYAVLPGPHSEY---LGFENELEPIIVVKKPLDFETVNNF 181
D D G +S Y + P H G + P +V+++ LD E
Sbjct: 150 ARYPLPEAVDPDV-GVNSLQSYQLSPNHHFSLDVQTGDNGAINPELVLERALDREEEAAH 208
Query: 182 TIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPI 241
+ L D G PP S + VTVLD +D P F + Y + ++ GT L T +
Sbjct: 209 HLVLTASDGGKPPRSSTVRIHVTVLDTNDNAPVFPHPIYRVKVLENMPPGTRLLT----V 264
Query: 242 SAADQDLGINAPLQYSSTG-DHKQ--LIVVNKDTGQVAATKQLIAELDPSVTIVLKATQV 298
+A+D D GIN + Y + KQ L +N++TG+++ K L E + ++A V
Sbjct: 265 TASDPDEGINGKVAYKFRKINEKQTPLFQLNENTGEISIAKSLDYEECSFYEMEIQAEDV 324
Query: 299 DNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTE 358
A L + + V E + PG+V+ L+ Q++
Sbjct: 325 G-------ALLGRTKLLISVEDVNDNRPEVIITSLFSPVLENSLPGTVIAFLSVHDQDSG 377
Query: 359 FRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTD----SISNDTA 414
+ + + F + +I N ++ R+ LD E S Y VM +D +S +T
Sbjct: 378 KNGQVVCYTRDNLPFKLEKSIGNYYRLVTRKYLDRENVSIYNITVMASDLGTPPLSTET- 436
Query: 415 SINISVEDVNEWEPRFRHPQY 435
I + V D+N+ P F H Y
Sbjct: 437 QIALHVADINDNPPTFPHASY 457
Score = 67.3 bits (157), Expect = 2e-10
Identities = 75/315 (23%), Positives = 125/315 (39%), Gaps = 26/315 (8%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEK--GAAVGIVPGSKNLTLLRALDREEK 68
+ E++ G++I LSV+ S G + ++ + L + LDRE
Sbjct: 356 VLENSLPGTVIAFLSVHDQDSGKNGQVVCYTRDNLPFKLEKSIGNYYRLVTRKYLDRENV 415
Query: 69 IGPSNVY-VNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXX 127
++Y + V T S +++ V D+NDN P + A Y+ + E
Sbjct: 416 ----SIYNITVMASDLGTPPLSTETQIALHVADINDNPPTFPHASYSAYILENNLRGASI 471
Query: 128 XXXXXSDRDQPGPHSALHYAV----LPG-PHSEYLGFENELEPIIVVKKPLDFETVNNFT 182
D D ++ + Y+V L G P S Y+ ++ ++ + D+E + +
Sbjct: 472 FSLTAHDPDSQ-ENAQVTYSVTEDTLQGAPLSSYISINSDTG-VLYALQSFDYEQIRDLQ 529
Query: 183 IKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHY-------TALLPDDAEEGTFLT 235
+ + D G PPL S+ +L + VLD +D P+ Y L P AE G +T
Sbjct: 530 LLVTASDSGDPPLSSNMSLSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAERGYLVT 589
Query: 236 TSPGPISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLK 294
+ A D+D G NA L Y L V TG+V + L+ ++V+
Sbjct: 590 ----KVVAVDRDSGQNAWLSYRLLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVA 645
Query: 295 ATQVDNPDRYALATL 309
P A TL
Sbjct: 646 VQDHGQPPLSATVTL 660
Score = 58.8 bits (136), Expect = 8e-08
Identities = 54/212 (25%), Positives = 88/212 (41%), Gaps = 12/212 (5%)
Query: 96 VRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSE 155
+ V DVNDN P+ V E D+D + Y P
Sbjct: 335 ISVEDVNDNRPEVIITSLFSPVLENSLPGTVIAFLSVHDQDSGKNGQVVCYTRDNLPFKL 394
Query: 156 YLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKF 215
N +V +K LD E V+ + I + D G+PPL ++T + + V D +D P F
Sbjct: 395 EKSIGNYYR--LVTRKYLDRENVSIYNITVMASDLGTPPLSTETQIALHVADINDNPPTF 452
Query: 216 TYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQ------LIVVN 269
+ Y+A + ++ G + + ++A D D NA + YS T D Q I +N
Sbjct: 453 PHASYSAYILENNLRGASIFS----LTAHDPDSQENAQVTYSVTEDTLQGAPLSSYISIN 508
Query: 270 KDTGQVAATKQLIAELDPSVTIVLKATQVDNP 301
DTG + A + E + +++ A+ +P
Sbjct: 509 SDTGVLYALQSFDYEQIRDLQLLVTASDSGDP 540
Score = 33.1 bits (72), Expect = 4.5
Identities = 46/212 (21%), Positives = 85/212 (40%), Gaps = 13/212 (6%)
Query: 8 SFFISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQE---KGAAVG-IVPGSKNLTLLRAL 63
S +I E+ G+ I +L+ + S++ +T + E +GA + + + + +L AL
Sbjct: 458 SAYILENNLRGASIFSLTAHDPDSQENAQVTYSVTEDTLQGAPLSSYISINSDTGVLYAL 517
Query: 64 DREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQ-------WEGAPYAVR 116
+ ++ + V S + +S+ V D NDNAP+ +G+
Sbjct: 518 QSFDYEQIRDLQLLVTASDSGDPPLSSNMSLSLFVLDQNDNAPEILYPALPTDGSTGVEL 577
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFE 176
+ DRD G ++ L Y +L + + LD +
Sbjct: 578 APRSAERGYLVTKVVAVDRDS-GQNAWLSYRLLKASEPGLFSVGLHTGEVRTARALLDRD 636
Query: 177 TVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDA 208
+ ++ + VQD G PPL + TL V V D+
Sbjct: 637 ALKQ-SLVVAVQDHGQPPLSATVTLTVAVADS 667
>AF152328-1|AAD43722.1| 932|Homo sapiens protocadherin gamma A8
protein.
Length = 932
Score = 104 bits (249), Expect = 2e-21
Identities = 109/441 (24%), Positives = 183/441 (41%), Gaps = 30/441 (6%)
Query: 9 FFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAA--VGIVPGSKNLTLLRALDR 65
+ + E+T GS +G +S + G L +R+ +G + P S +L +DR
Sbjct: 33 YSVPEETDKGSFVGNISKDLGLDPRKLAKHGVRIVSRGRTQLFALNPRSGSLITAGRIDR 92
Query: 66 EEKIGPS-NVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXX 124
EE S +N+ D + V + + D+NDN P+++ V+++E
Sbjct: 93 EELCAQSPRCLININT---LVEDKGKLFGVEIEIIDINDNNPKFQVEDLEVKINEIAVPG 149
Query: 125 XXXXXXXXSDRDQPGPHSALHYAVLPGPHSEY---LGFENELEPIIVVKKPLDFETVNNF 181
D D G +S Y + P H G + P +V+++ LD E
Sbjct: 150 ARYPLPEAVDPDV-GVNSLQSYQLSPNHHFSLDVQTGDNGAINPELVLERALDREEEAAH 208
Query: 182 TIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPI 241
+ L D G PP S + VTVLD +D P F + Y + ++ GT L T +
Sbjct: 209 HLVLTASDGGKPPRSSTVRIHVTVLDTNDNAPVFPHPIYRVKVLENMPPGTRLLT----V 264
Query: 242 SAADQDLGINAPLQYSSTG-DHKQ--LIVVNKDTGQVAATKQLIAELDPSVTIVLKATQV 298
+A+D D GIN + Y + KQ L +N++TG+++ K L E + ++A V
Sbjct: 265 TASDPDEGINGKVAYKFRKINEKQTPLFQLNENTGEISIAKSLDYEECSFYEMEIQAEDV 324
Query: 299 DNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTE 358
A L + + V E + PG+V+ L+ Q++
Sbjct: 325 G-------ALLGRTKLLISVEDVNDNRPEVIITSLFSPVLENSLPGTVIAFLSVHDQDSG 377
Query: 359 FRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTD----SISNDTA 414
+ + + F + +I N ++ R+ LD E S Y VM +D +S +T
Sbjct: 378 KNGQVVCYTRDNLPFKLEKSIGNYYRLVTRKYLDRENVSIYNITVMASDLGTPPLSTET- 436
Query: 415 SINISVEDVNEWEPRFRHPQY 435
I + V D+N+ P F H Y
Sbjct: 437 QIALHVADINDNPPTFPHASY 457
Score = 67.3 bits (157), Expect = 2e-10
Identities = 75/315 (23%), Positives = 125/315 (39%), Gaps = 26/315 (8%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEK--GAAVGIVPGSKNLTLLRALDREEK 68
+ E++ G++I LSV+ S G + ++ + L + LDRE
Sbjct: 356 VLENSLPGTVIAFLSVHDQDSGKNGQVVCYTRDNLPFKLEKSIGNYYRLVTRKYLDRENV 415
Query: 69 IGPSNVY-VNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXX 127
++Y + V T S +++ V D+NDN P + A Y+ + E
Sbjct: 416 ----SIYNITVMASDLGTPPLSTETQIALHVADINDNPPTFPHASYSAYILENNLRGASI 471
Query: 128 XXXXXSDRDQPGPHSALHYAV----LPG-PHSEYLGFENELEPIIVVKKPLDFETVNNFT 182
D D ++ + Y+V L G P S Y+ ++ ++ + D+E + +
Sbjct: 472 FSLTAHDPDSQ-ENAQVTYSVTEDTLQGAPLSSYISINSDTG-VLYALQSFDYEQIRDLQ 529
Query: 183 IKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHY-------TALLPDDAEEGTFLT 235
+ + D G PPL S+ +L + VLD +D P+ Y L P AE G +T
Sbjct: 530 LLVTASDSGDPPLSSNMSLSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAERGYLVT 589
Query: 236 TSPGPISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLK 294
+ A D+D G NA L Y L V TG+V + L+ ++V+
Sbjct: 590 ----KVVAVDRDSGQNAWLSYRLLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVA 645
Query: 295 ATQVDNPDRYALATL 309
P A TL
Sbjct: 646 VQDHGQPPLSATVTL 660
Score = 58.8 bits (136), Expect = 8e-08
Identities = 54/212 (25%), Positives = 88/212 (41%), Gaps = 12/212 (5%)
Query: 96 VRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSE 155
+ V DVNDN P+ V E D+D + Y P
Sbjct: 335 ISVEDVNDNRPEVIITSLFSPVLENSLPGTVIAFLSVHDQDSGKNGQVVCYTRDNLPFKL 394
Query: 156 YLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKF 215
N +V +K LD E V+ + I + D G+PPL ++T + + V D +D P F
Sbjct: 395 EKSIGNYYR--LVTRKYLDRENVSIYNITVMASDLGTPPLSTETQIALHVADINDNPPTF 452
Query: 216 TYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQ------LIVVN 269
+ Y+A + ++ G + + ++A D D NA + YS T D Q I +N
Sbjct: 453 PHASYSAYILENNLRGASIFS----LTAHDPDSQENAQVTYSVTEDTLQGAPLSSYISIN 508
Query: 270 KDTGQVAATKQLIAELDPSVTIVLKATQVDNP 301
DTG + A + E + +++ A+ +P
Sbjct: 509 SDTGVLYALQSFDYEQIRDLQLLVTASDSGDP 540
Score = 33.1 bits (72), Expect = 4.5
Identities = 46/212 (21%), Positives = 85/212 (40%), Gaps = 13/212 (6%)
Query: 8 SFFISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQE---KGAAVG-IVPGSKNLTLLRAL 63
S +I E+ G+ I +L+ + S++ +T + E +GA + + + + +L AL
Sbjct: 458 SAYILENNLRGASIFSLTAHDPDSQENAQVTYSVTEDTLQGAPLSSYISINSDTGVLYAL 517
Query: 64 DREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQ-------WEGAPYAVR 116
+ ++ + V S + +S+ V D NDNAP+ +G+
Sbjct: 518 QSFDYEQIRDLQLLVTASDSGDPPLSSNMSLSLFVLDQNDNAPEILYPALPTDGSTGVEL 577
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFE 176
+ DRD G ++ L Y +L + + LD +
Sbjct: 578 APRSAERGYLVTKVVAVDRDS-GQNAWLSYRLLKASEPGLFSVGLHTGEVRTARALLDRD 636
Query: 177 TVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDA 208
+ ++ + VQD G PPL + TL V V D+
Sbjct: 637 ALKQ-SLVVAVQDHGQPPLSATVTLTVAVADS 667
>AB002325-1|BAA20785.2| 898|Homo sapiens KIAA0327 protein protein.
Length = 898
Score = 104 bits (249), Expect = 2e-21
Identities = 109/441 (24%), Positives = 183/441 (41%), Gaps = 30/441 (6%)
Query: 9 FFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAA--VGIVPGSKNLTLLRALDR 65
+ + E+T GS +G +S + G L +R+ +G + P S +L +DR
Sbjct: 111 YSVPEETDKGSFVGNISKDLGLDPRKLAKHGVRIVSRGRTQLFALNPRSGSLITAGRIDR 170
Query: 66 EEKIGPS-NVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXX 124
EE S +N+ D + V + + D+NDN P+++ V+++E
Sbjct: 171 EELCAQSPRCLININT---LVEDKGKLFGVEIEIIDINDNNPKFQVEDLEVKINEIAVPG 227
Query: 125 XXXXXXXXSDRDQPGPHSALHYAVLPGPHSEY---LGFENELEPIIVVKKPLDFETVNNF 181
D D G +S Y + P H G + P +V+++ LD E
Sbjct: 228 ARYPLPEAVDPDV-GVNSLQSYQLSPNHHFSLDVQTGDNGAINPELVLERALDREEEAAH 286
Query: 182 TIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPI 241
+ L D G PP S + VTVLD +D P F + Y + ++ GT L T +
Sbjct: 287 HLVLTASDGGKPPRSSTVRIHVTVLDTNDNAPVFPHPIYRVKVLENMPPGTRLLT----V 342
Query: 242 SAADQDLGINAPLQYSSTG-DHKQ--LIVVNKDTGQVAATKQLIAELDPSVTIVLKATQV 298
+A+D D GIN + Y + KQ L +N++TG+++ K L E + ++A V
Sbjct: 343 TASDPDEGINGKVAYKFRKINEKQTPLFQLNENTGEISIAKSLDYEECSFYEMEIQAEDV 402
Query: 299 DNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTE 358
A L + + V E + PG+V+ L+ Q++
Sbjct: 403 G-------ALLGRTKLLISVEDVNDNRPEVIITSLFSPVLENSLPGTVIAFLSVHDQDSG 455
Query: 359 FRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTD----SISNDTA 414
+ + + F + +I N ++ R+ LD E S Y VM +D +S +T
Sbjct: 456 KNGQVVCYTRDNLPFKLEKSIGNYYRLVTRKYLDRENVSIYNITVMASDLGTPPLSTET- 514
Query: 415 SINISVEDVNEWEPRFRHPQY 435
I + V D+N+ P F H Y
Sbjct: 515 QIALHVADINDNPPTFPHASY 535
Score = 67.3 bits (157), Expect = 2e-10
Identities = 75/315 (23%), Positives = 125/315 (39%), Gaps = 26/315 (8%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEK--GAAVGIVPGSKNLTLLRALDREEK 68
+ E++ G++I LSV+ S G + ++ + L + LDRE
Sbjct: 434 VLENSLPGTVIAFLSVHDQDSGKNGQVVCYTRDNLPFKLEKSIGNYYRLVTRKYLDRENV 493
Query: 69 IGPSNVY-VNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXX 127
++Y + V T S +++ V D+NDN P + A Y+ + E
Sbjct: 494 ----SIYNITVMASDLGTPPLSTETQIALHVADINDNPPTFPHASYSAYILENNLRGASI 549
Query: 128 XXXXXSDRDQPGPHSALHYAV----LPG-PHSEYLGFENELEPIIVVKKPLDFETVNNFT 182
D D ++ + Y+V L G P S Y+ ++ ++ + D+E + +
Sbjct: 550 FSLTAHDPDSQ-ENAQVTYSVTEDTLQGAPLSSYISINSDTG-VLYALQSFDYEQIRDLQ 607
Query: 183 IKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHY-------TALLPDDAEEGTFLT 235
+ + D G PPL S+ +L + VLD +D P+ Y L P AE G +T
Sbjct: 608 LLVTASDSGDPPLSSNMSLSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAERGYLVT 667
Query: 236 TSPGPISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLK 294
+ A D+D G NA L Y L V TG+V + L+ ++V+
Sbjct: 668 ----KVVAVDRDSGQNAWLSYRLLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVA 723
Query: 295 ATQVDNPDRYALATL 309
P A TL
Sbjct: 724 VQDHGQPPLSATVTL 738
Score = 58.8 bits (136), Expect = 8e-08
Identities = 54/212 (25%), Positives = 88/212 (41%), Gaps = 12/212 (5%)
Query: 96 VRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSE 155
+ V DVNDN P+ V E D+D + Y P
Sbjct: 413 ISVEDVNDNRPEVIITSLFSPVLENSLPGTVIAFLSVHDQDSGKNGQVVCYTRDNLPFKL 472
Query: 156 YLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKF 215
N +V +K LD E V+ + I + D G+PPL ++T + + V D +D P F
Sbjct: 473 EKSIGNYYR--LVTRKYLDRENVSIYNITVMASDLGTPPLSTETQIALHVADINDNPPTF 530
Query: 216 TYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQ------LIVVN 269
+ Y+A + ++ G + + ++A D D NA + YS T D Q I +N
Sbjct: 531 PHASYSAYILENNLRGASIFS----LTAHDPDSQENAQVTYSVTEDTLQGAPLSSYISIN 586
Query: 270 KDTGQVAATKQLIAELDPSVTIVLKATQVDNP 301
DTG + A + E + +++ A+ +P
Sbjct: 587 SDTGVLYALQSFDYEQIRDLQLLVTASDSGDP 618
Score = 33.1 bits (72), Expect = 4.5
Identities = 46/212 (21%), Positives = 85/212 (40%), Gaps = 13/212 (6%)
Query: 8 SFFISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQE---KGAAVG-IVPGSKNLTLLRAL 63
S +I E+ G+ I +L+ + S++ +T + E +GA + + + + +L AL
Sbjct: 536 SAYILENNLRGASIFSLTAHDPDSQENAQVTYSVTEDTLQGAPLSSYISINSDTGVLYAL 595
Query: 64 DREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQ-------WEGAPYAVR 116
+ ++ + V S + +S+ V D NDNAP+ +G+
Sbjct: 596 QSFDYEQIRDLQLLVTASDSGDPPLSSNMSLSLFVLDQNDNAPEILYPALPTDGSTGVEL 655
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFE 176
+ DRD G ++ L Y +L + + LD +
Sbjct: 656 APRSAERGYLVTKVVAVDRDS-GQNAWLSYRLLKASEPGLFSVGLHTGEVRTARALLDRD 714
Query: 177 TVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDA 208
+ ++ + VQD G PPL + TL V V D+
Sbjct: 715 ALKQ-SLVVAVQDHGQPPLSATVTLTVAVADS 745
>U59325-1|AAB02933.1| 790|Homo sapiens cadherin-14 protein.
Length = 790
Score = 103 bits (248), Expect = 2e-21
Identities = 109/446 (24%), Positives = 189/446 (42%), Gaps = 33/446 (7%)
Query: 3 GGAVESFFISEDT--PIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLL 60
G FF+ E+ P +G L N D + L + G I + ++
Sbjct: 54 GWVWNQFFVLEEHMGPDPQYVGKLHSNSDKGDGSVKYILTGEGAGTIFIIDDTTGDIHST 113
Query: 61 RALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVS---VRVWDVNDNAPQWEGAPYAVRV 117
++LDRE+K ++ ++ + RRT P + P S ++V D+NDNAP++ PY V V
Sbjct: 114 KSLDREQK---THYVLHAQAIDRRTNKP--LEPESEFIIKVQDINDNAPKFTDGPYIVTV 168
Query: 118 SETXXXXXXXXXXXXSDRDQP--GPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDF 175
E +D D P G + + Y++L G Y + + I +D
Sbjct: 169 PEMSDMGTSVLQVTATDADDPTYGNSARVVYSILQG--QPYFSVDPKTGVIRTALHNMDR 226
Query: 176 ETVNNFTIKLRVQDQGSP--PLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTF 233
E ++++ ++ +D L TT+ +T+ D +D P+F +HY +P+ A+ G
Sbjct: 227 EAREHYSVVIQAKDMAGQVGGLSGSTTVNITLTDVNDNPPRFPQKHYQLYVPESAQVG-- 284
Query: 234 LTTSPGPISAADQDLGINAPLQYS-STGDHKQLIVVNKD----TGQVAATKQLIAELDPS 288
++ G I A D D G NA + YS GD + ++ D G ++ K L E S
Sbjct: 285 --SAVGKIKANDADTGSNADMTYSIINGDGMGIFSISTDKETREGILSLKKPLNYEKKKS 342
Query: 289 VTIVLKATQVDNPDRYA-LATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVL 347
T+ ++ R++ L F+ Y V E A G+V+
Sbjct: 343 YTLNIEGANTHLDFRFSHLGPFKDATMLKIIVGDVDEPPLFSMPSYLMEVYENAKIGTVV 402
Query: 348 LTLTTVPQNTEFRESPLQFYVSDRSFLDKF--AINNAGEVILRRSLDYETTSNYFYQVMV 405
T+ + Q+ + S ++++++ D+F N G + + LD E T Y V
Sbjct: 403 GTV--LAQDPDSTNSLVRYFINYNVEDDRFFNIDANTGTIRTTKVLDREETPWYNITVTA 460
Query: 406 TDSISNDTAS---INISVEDVNEWEP 428
++ + D S + I V DVN+ P
Sbjct: 461 SEIDNPDLLSHVTVGIRVLDVNDNPP 486
Score = 77.8 bits (183), Expect = 2e-13
Identities = 83/369 (22%), Positives = 159/369 (43%), Gaps = 34/369 (9%)
Query: 58 TLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRV 117
T L +DRE + S V + + + S V++ + DVNDN P++ Y + V
Sbjct: 219 TALHNMDREAREHYS-VVIQAKDMAGQVGGLSGSTTVNITLTDVNDNPPRFPQKHYQLYV 277
Query: 118 SETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEP---IIVVKKPLD 174
E+ +D D G ++ + Y+++ G + E I+ +KKPL+
Sbjct: 278 PESAQVGSAVGKIKANDADT-GSNADMTYSIINGDGMGIFSISTDKETREGILSLKKPLN 336
Query: 175 FETVNNFTIKLRVQDQGSP-------PLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDD 227
+E ++T+ + + P T L++ V D D+ P F+ Y + ++
Sbjct: 337 YEKKKSYTLNIEGANTHLDFRFSHLGPFKDATMLKIIVGDVDEP-PLFSMPSYLMEVYEN 395
Query: 228 AEEGTFLTTSPGPISAADQDLGINAPLQY--SSTGDHKQLIVVNKDTGQVAATKQLIAEL 285
A+ GT + G + A D D N+ ++Y + + + ++ +TG + TK L E
Sbjct: 396 AKIGTVV----GTVLAQDPD-STNSLVRYFINYNVEDDRFFNIDANTGTIRTTKVLDREE 450
Query: 286 DPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGS 345
P I + A+++DNPD + T+ ++Y V E + PG
Sbjct: 451 TPWYNITVTASEIDNPDLLSHVTVGIRVLDVNDNPPELA------REYDIIVCENSKPGQ 504
Query: 346 VLLTLTTVPQNTEFRESP-LQFYVSDR-----SFLDKFAINNAGEVILRRSLDYETTSN- 398
V+ T++ ++ +F P F++ +R +F K +N ++ RR T +
Sbjct: 505 VIHTISATDKD-DFANGPRFNFFLDERLPVNPNFTLKDNEDNTASILTRRRRFSRTVQDV 563
Query: 399 YFYQVMVTD 407
Y+ +M++D
Sbjct: 564 YYLPIMISD 572
Score = 41.1 bits (92), Expect = 0.017
Identities = 45/203 (22%), Positives = 81/203 (39%), Gaps = 14/203 (6%)
Query: 11 ISEDTPIGSIIGT-LSVNGDPSEDLGDITLRLQ-EKGAAVGIVPGSKNLTLLRALDREEK 68
+ E+ IG+++GT L+ + D + L + E I + + + LDREE
Sbjct: 392 VYENAKIGTVVGTVLAQDPDSTNSLVRYFINYNVEDDRFFNIDANTGTIRTTKVLDREE- 450
Query: 69 IGPSNVYVNVRCDRRRTTDPSFV--IPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXX 126
+ N+ +P + + V +RV DVNDN P+ Y + V E
Sbjct: 451 ----TPWYNITVTASEIDNPDLLSHVTVGIRVLDVNDNPPEL-AREYDIIVCENSKPGQV 505
Query: 127 XXXXXXSDRDQ--PGP--HSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFT 182
+D+D GP + L + P+ E+ I+ ++ + +
Sbjct: 506 IHTISATDKDDFANGPRFNFFLDERLPVNPNFTLKDNEDNTASILTRRRRFSRTVQDVYY 565
Query: 183 IKLRVQDQGSPPLYSDTTLQVTV 205
+ + + D G P L S +TL + V
Sbjct: 566 LPIMISDGGIPSLSSSSTLTIRV 588
Score = 34.3 bits (75), Expect = 2.0
Identities = 42/201 (20%), Positives = 79/201 (39%), Gaps = 13/201 (6%)
Query: 244 ADQDLGINAPLQYSSTGDHKQLI-VVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPD 302
++ D G + ++Y TG+ I +++ TG + +TK L + + VL A +D
Sbjct: 79 SNSDKG-DGSVKYILTGEGAGTIFIIDDTTGDIHSTKSL--DREQKTHYVLHAQAIDRRT 135
Query: 303 RYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRES 362
L +FT Y TV E + G+ +L +T + +
Sbjct: 136 NKPLEP--ESEFIIKVQDINDNAPKFTDGPYIVTVPEMSDMGTSVLQVTATDADDPTYGN 193
Query: 363 PLQFYVSDRSFLDKFAINNAGEVILR--RSLDYETTSNYFYQVMVTDSIS-----NDTAS 415
+ S F+++ VI ++D E +Y + D + + +
Sbjct: 194 SARVVYSILQGQPYFSVDPKTGVIRTALHNMDREAREHYSVVIQAKDMAGQVGGLSGSTT 253
Query: 416 INISVEDVNEWEPRFRHPQYE 436
+NI++ DVN+ PRF Y+
Sbjct: 254 VNITLTDVNDNPPRFPQKHYQ 274
>BC031051-1|AAH31051.1| 790|Homo sapiens cadherin 18, type 2
protein.
Length = 790
Score = 103 bits (248), Expect = 2e-21
Identities = 109/446 (24%), Positives = 189/446 (42%), Gaps = 33/446 (7%)
Query: 3 GGAVESFFISEDT--PIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLL 60
G FF+ E+ P +G L N D + L + G I + ++
Sbjct: 54 GWVWNQFFVLEEHMGPDPQYVGKLHSNSDKGDGSVKYILTGEGAGTIFIIDDTTGDIHST 113
Query: 61 RALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVS---VRVWDVNDNAPQWEGAPYAVRV 117
++LDRE+K ++ ++ + RRT P + P S ++V D+NDNAP++ PY V V
Sbjct: 114 KSLDREQK---THYVLHAQAIDRRTNKP--LEPESEFIIKVQDINDNAPKFTDGPYIVTV 168
Query: 118 SETXXXXXXXXXXXXSDRDQP--GPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDF 175
E +D D P G + + Y++L G Y + + I +D
Sbjct: 169 PEMSDMGTSVLQVTATDADDPTYGNSARVVYSILQG--QPYFSVDPKTGVIRTALHNMDG 226
Query: 176 ETVNNFTIKLRVQDQGSPP--LYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTF 233
E ++++ ++ +D L TT+ +T+ D +D P+F +HY +P+ A+ G
Sbjct: 227 EAREHYSVVIQAKDMAGQVGGLSGSTTVNITLTDVNDNTPRFPQKHYQLYVPESAQVG-- 284
Query: 234 LTTSPGPISAADQDLGINAPLQYS-STGDHKQLIVVNKD----TGQVAATKQLIAELDPS 288
++ G I A D D G NA + YS GD + ++ D G ++ K L E S
Sbjct: 285 --SAVGKIKANDADTGSNADMTYSIINGDGMGIFSISTDKETREGILSLKKPLNYEKKKS 342
Query: 289 VTIVLKATQVDNPDRYA-LATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVL 347
T+ ++ R++ L F+ Y V E A G+V+
Sbjct: 343 YTLNIEGANTHLDFRFSHLGPFKDATMLKIIVGDVDEPPLFSMPSYLMEVYENAKIGTVV 402
Query: 348 LTLTTVPQNTEFRESPLQFYVSDRSFLDKF--AINNAGEVILRRSLDYETTSNYFYQVMV 405
T+ + Q+ + S ++++++ D+F N G + + LD E T Y V
Sbjct: 403 GTV--LAQDPDSINSLVRYFINYNVEDDRFFNIDANTGTIRTTKVLDREETPWYNITVTA 460
Query: 406 TDSISNDTAS---INISVEDVNEWEP 428
++ + D S + I V DVN+ P
Sbjct: 461 SEIDNPDLLSHVTVGIRVLDVNDNPP 486
Score = 79.8 bits (188), Expect = 4e-14
Identities = 76/333 (22%), Positives = 147/333 (44%), Gaps = 33/333 (9%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
V++ + DVNDN P++ Y + V E+ +D D G ++ + Y+++ G
Sbjct: 254 VNITLTDVNDNTPRFPQKHYQLYVPESAQVGSAVGKIKANDADT-GSNADMTYSIINGDG 312
Query: 154 SEYLGFENELEP---IIVVKKPLDFETVNNFTIKLRVQDQGSP-------PLYSDTTLQV 203
+ E I+ +KKPL++E ++T+ + + P T L++
Sbjct: 313 MGIFSISTDKETREGILSLKKPLNYEKKKSYTLNIEGANTHLDFRFSHLGPFKDATMLKI 372
Query: 204 TVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQY--SSTGD 261
V D D+ P F+ Y + ++A+ GT + G + A D D IN+ ++Y + +
Sbjct: 373 IVGDVDEP-PLFSMPSYLMEVYENAKIGTVV----GTVLAQDPD-SINSLVRYFINYNVE 426
Query: 262 HKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXX 321
+ ++ +TG + TK L E P I + A+++DNPD + T+
Sbjct: 427 DDRFFNIDANTGTIRTTKVLDREETPWYNITVTASEIDNPDLLSHVTVGIRVLDVNDNPP 486
Query: 322 XXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESP-LQFYVSDR-----SFLD 375
++Y V E + PG V+ T++ ++ +F P F++ +R +F
Sbjct: 487 ELA------REYDIIVCENSKPGQVIHTISATDKD-DFANGPRFNFFLDERLPVNPNFTL 539
Query: 376 KFAINNAGEVILRRSLDYETTSN-YFYQVMVTD 407
K +N ++ RR T + Y+ +M++D
Sbjct: 540 KDNEDNTASILTRRRRFSRTVQDVYYLPIMISD 572
Score = 39.9 bits (89), Expect = 0.039
Identities = 45/203 (22%), Positives = 80/203 (39%), Gaps = 14/203 (6%)
Query: 11 ISEDTPIGSIIGT-LSVNGDPSEDLGDITLRLQ-EKGAAVGIVPGSKNLTLLRALDREEK 68
+ E+ IG+++GT L+ + D L + E I + + + LDREE
Sbjct: 392 VYENAKIGTVVGTVLAQDPDSINSLVRYFINYNVEDDRFFNIDANTGTIRTTKVLDREE- 450
Query: 69 IGPSNVYVNVRCDRRRTTDPSFV--IPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXX 126
+ N+ +P + + V +RV DVNDN P+ Y + V E
Sbjct: 451 ----TPWYNITVTASEIDNPDLLSHVTVGIRVLDVNDNPPEL-AREYDIIVCENSKPGQV 505
Query: 127 XXXXXXSDRDQ--PGP--HSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFT 182
+D+D GP + L + P+ E+ I+ ++ + +
Sbjct: 506 IHTISATDKDDFANGPRFNFFLDERLPVNPNFTLKDNEDNTASILTRRRRFSRTVQDVYY 565
Query: 183 IKLRVQDQGSPPLYSDTTLQVTV 205
+ + + D G P L S +TL + V
Sbjct: 566 LPIMISDGGIPSLSSSSTLTIRV 588
Score = 33.9 bits (74), Expect = 2.6
Identities = 42/201 (20%), Positives = 79/201 (39%), Gaps = 13/201 (6%)
Query: 244 ADQDLGINAPLQYSSTGDHKQLI-VVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPD 302
++ D G + ++Y TG+ I +++ TG + +TK L + + VL A +D
Sbjct: 79 SNSDKG-DGSVKYILTGEGAGTIFIIDDTTGDIHSTKSL--DREQKTHYVLHAQAIDRRT 135
Query: 303 RYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRES 362
L +FT Y TV E + G+ +L +T + +
Sbjct: 136 NKPLEP--ESEFIIKVQDINDNAPKFTDGPYIVTVPEMSDMGTSVLQVTATDADDPTYGN 193
Query: 363 PLQFYVSDRSFLDKFAINNAGEVILR--RSLDYETTSNYFYQVMVTDSIS-----NDTAS 415
+ S F+++ VI ++D E +Y + D + + +
Sbjct: 194 SARVVYSILQGQPYFSVDPKTGVIRTALHNMDGEAREHYSVVIQAKDMAGQVGGLSGSTT 253
Query: 416 INISVEDVNEWEPRFRHPQYE 436
+NI++ DVN+ PRF Y+
Sbjct: 254 VNITLTDVNDNTPRFPQKHYQ 274
>BX537422-1|CAD97664.1| 1203|Homo sapiens hypothetical protein
protein.
Length = 1203
Score = 102 bits (245), Expect = 5e-21
Identities = 108/449 (24%), Positives = 170/449 (37%), Gaps = 31/449 (6%)
Query: 91 VIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLP 150
+I + + V D NDNAP + + + E +D D G + HY +L
Sbjct: 125 LIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDT-GFNGVQHYELLN 183
Query: 151 GPHSEYLGF----ENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVL 206
G L E E P ++V++ LD E + + +K++V+D G+P S LQVTV
Sbjct: 184 GQSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVS 243
Query: 207 DADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQY----SSTGDH 262
D +D P F +P++A G TS + A D D+G NA ++Y
Sbjct: 244 DVNDNRPVFKEGQVEVHIPENAPVG----TSVIQLHATDADIGSNAEIRYIFGAQVAPAT 299
Query: 263 KQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQV--DNPDRYALATLXXXXXXXXXXX 320
K+L +N TG + + LD T + K T + D A AT+
Sbjct: 300 KRLFALNNTTGLITVQR----SLDREETAIHKVTVLASDGSSTPARATVTINVTDVNDNP 355
Query: 321 XXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTV-PQNTEFRESPLQFYVSDRSFLDKFAI 379
T P + + L TV ++T+ + F + F K
Sbjct: 356 PNIDLRYIISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVY 415
Query: 380 NNAGEVILRRSLDYETTSNYFYQVMVTDS---ISNDTASINISVEDVNEWEPRFRHPQYE 436
+N + LDYE T + ++++ +DS N TA + + +ED N+ P F P E
Sbjct: 416 DNQYLLETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIE 475
Query: 437 FEXXXXXXXXXXXXXXXXXXXXVAHDGDAGTLA--LSLAGQHARMFYINASGDLFLREEA 494
A D D+G A + G +A F ++ +
Sbjct: 476 LSVSENNRRGLYLTTIS------ATDEDSGKNADIVYQLGPNASFFDLDRKTGVLTASRV 529
Query: 495 IGNLNSSSLHLVATAIDSGIPPRQTSVPV 523
TA D+G PP Q+ V
Sbjct: 530 FDREEQERFIFTVTARDNGTPPLQSQAAV 558
Score = 79.8 bits (188), Expect = 4e-14
Identities = 67/298 (22%), Positives = 122/298 (40%), Gaps = 10/298 (3%)
Query: 10 FISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEKI 69
++SE P+ + I ++V+ D D+ + E+ + N LL +
Sbjct: 372 YLSEKDPVNTKIALITVS-DKDTDVNGKVICFIEREVPFHLKAVYDNQYLLETSSLLDYE 430
Query: 70 GPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXX 129
G + + V V++ D NDN P + + VSE
Sbjct: 431 GTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTT 490
Query: 130 XXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQD 189
+D D G ++ + Y + GP++ + + + ++ + D E F + +D
Sbjct: 491 ISATDEDS-GKNADIVYQL--GPNASFFDLDRKTG-VLTASRVFDREEQERFIFTVTARD 546
Query: 190 QGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLG 249
G+PPL S + VTVLD +D +PKFT+ H+ + ++ + ++ G I+ D D G
Sbjct: 547 NGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPK----YSTVGVITVTDADAG 602
Query: 250 INAPLQYSSTGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALA 307
N + S D+ V++ +G + + E S T +KAT P R + A
Sbjct: 603 ENKAVTLSILNDNDN-FVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTA 659
Score = 63.3 bits (147), Expect = 4e-09
Identities = 65/269 (24%), Positives = 110/269 (40%), Gaps = 15/269 (5%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEKIG 70
+SE+ G + T+S + S DI +L + + + LT R DREE+
Sbjct: 478 VSENNRRGLYLTTISATDEDSGKNADIVYQLGPNASFFDLDRKTGVLTASRVFDREEQ-- 535
Query: 71 PSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXX 130
V T V V V D NDN+P++ + VSE
Sbjct: 536 -ERFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVI 594
Query: 131 XXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQ 190
+D D G + A+ ++L + L + +I D E +++T ++ D
Sbjct: 595 TVTDADA-GENKAVTLSILNDNDNFVL---DPYSGVIKSNVSFDREQQSSYTFDVKATDG 650
Query: 191 GSPPLYSDTTLQVTVLDADDQNPKFTYEHYTA---LLPDDAEEGTFLTTSPGPISAADQD 247
G PP S + + V+D +D +P L+P A G+ + + A D D
Sbjct: 651 GQPPRSSTAKVTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPGSVV----AEVFAVDVD 706
Query: 248 LGINAPLQYS-STGDHKQLIVVNKDTGQV 275
G+NA L+Y+ +G++K L ++ TG +
Sbjct: 707 TGMNAELKYTIVSGNNKGLFRIDPVTGNI 735
Score = 55.2 bits (127), Expect = 1e-06
Identities = 94/477 (19%), Positives = 167/477 (35%), Gaps = 27/477 (5%)
Query: 57 LTLLRALDREEKIGPSNVYV-NVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAV 115
L + + LDRE+K + YV ++ + T S + V V DVNDN P ++ V
Sbjct: 204 LIVQQNLDREQK----DTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEV 259
Query: 116 RVSETXXXXXXXXXXXXSDRDQPGPHSALHY--AVLPGPHSEYLGFENELEPIIVVKKPL 173
+ E +D D G ++ + Y P ++ L N +I V++ L
Sbjct: 260 HIPENAPVGTSVIQLHATDAD-IGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQRSL 318
Query: 174 DFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDA--EEG 231
D E + + D S P + T+ VT D +D P + + + E
Sbjct: 319 DREETAIHKVTVLASDGSSTPARATVTINVT--DVNDNPPNIDLRYIISPINGTVYLSEK 376
Query: 232 TFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLI-AELDPSVT 290
+ T I+ +D+D +N + + + D + T L+ E +
Sbjct: 377 DPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYLLETSSLLDYEGTKEFS 436
Query: 291 IVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTL 350
+ A+ P A + F Q +VSE G L T+
Sbjct: 437 FKIVASDSGKPSLNQTALVRVKLEDENDNPPI-----FNQPVIELSVSENNRRGLYLTTI 491
Query: 351 TTVPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSIS 410
+ +++ + + SF D G + R D E + + V D+ +
Sbjct: 492 SATDEDSGKNADIVYQLGPNASFFD--LDRKTGVLTASRVFDREEQERFIFTVTARDNGT 549
Query: 411 ---NDTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGDAGT 467
A++ ++V D N+ P+F H ++F A G+
Sbjct: 550 PPLQSQAAVIVTVLDENDNSPKFTHNHFQF---FVSENLPKYSTVGVITVTDADAGENKA 606
Query: 468 LALSLAGQHARMFYINASGDLFLREEAIGNLNSSSLHLVATAIDSGIPPRQTSVPVT 524
+ LS+ + F ++ + + SS A D G PPR ++ VT
Sbjct: 607 VTLSILNDNDN-FVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVT 662
Score = 35.9 bits (79), Expect = 0.64
Identities = 26/98 (26%), Positives = 46/98 (46%), Gaps = 3/98 (3%)
Query: 9 FFISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEK 68
FF+SE+ P S +G ++V + + +TL + + P S + + DRE++
Sbjct: 579 FFVSENLPKYSTVGVITVTDADAGENKAVTLSILNDNDNFVLDPYSGVIKSNVSFDREQQ 638
Query: 69 IGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAP 106
S+ +V+ S V++ V DVNDN+P
Sbjct: 639 ---SSYTFDVKATDGGQPPRSSTAKVTINVMDVNDNSP 673
>AL603863-3|CAM17491.1| 1237|Homo sapiens protocadherin 9 protein.
Length = 1237
Score = 102 bits (245), Expect = 5e-21
Identities = 108/449 (24%), Positives = 170/449 (37%), Gaps = 31/449 (6%)
Query: 91 VIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLP 150
+I + + V D NDNAP + + + E +D D G + HY +L
Sbjct: 125 LIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDT-GFNGVQHYELLN 183
Query: 151 GPHSEYLGF----ENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVL 206
G L E E P ++V++ LD E + + +K++V+D G+P S LQVTV
Sbjct: 184 GQSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVS 243
Query: 207 DADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQY----SSTGDH 262
D +D P F +P++A G TS + A D D+G NA ++Y
Sbjct: 244 DVNDNRPVFKEGQVEVHIPENAPVG----TSVIQLHATDADIGSNAEIRYIFGAQVAPAT 299
Query: 263 KQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQV--DNPDRYALATLXXXXXXXXXXX 320
K+L +N TG + + LD T + K T + D A AT+
Sbjct: 300 KRLFALNNTTGLITVQR----SLDREETAIHKVTVLASDGSSTPARATVTINVTDVNDNP 355
Query: 321 XXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTV-PQNTEFRESPLQFYVSDRSFLDKFAI 379
T P + + L TV ++T+ + F + F K
Sbjct: 356 PNIDLRYIISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVY 415
Query: 380 NNAGEVILRRSLDYETTSNYFYQVMVTDS---ISNDTASINISVEDVNEWEPRFRHPQYE 436
+N + LDYE T + ++++ +DS N TA + + +ED N+ P F P E
Sbjct: 416 DNQYLLETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIE 475
Query: 437 FEXXXXXXXXXXXXXXXXXXXXVAHDGDAGTLA--LSLAGQHARMFYINASGDLFLREEA 494
A D D+G A + G +A F ++ +
Sbjct: 476 LSVSENNRRGLYLTTIS------ATDEDSGKNADIVYQLGPNASFFDLDRKTGVLTASRV 529
Query: 495 IGNLNSSSLHLVATAIDSGIPPRQTSVPV 523
TA D+G PP Q+ V
Sbjct: 530 FDREEQERFIFTVTARDNGTPPLQSQAAV 558
Score = 79.8 bits (188), Expect = 4e-14
Identities = 67/298 (22%), Positives = 122/298 (40%), Gaps = 10/298 (3%)
Query: 10 FISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEKI 69
++SE P+ + I ++V+ D D+ + E+ + N LL +
Sbjct: 372 YLSEKDPVNTKIALITVS-DKDTDVNGKVICFIEREVPFHLKAVYDNQYLLETSSLLDYE 430
Query: 70 GPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXX 129
G + + V V++ D NDN P + + VSE
Sbjct: 431 GTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTT 490
Query: 130 XXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQD 189
+D D G ++ + Y + GP++ + + + ++ + D E F + +D
Sbjct: 491 ISATDEDS-GKNADIVYQL--GPNASFFDLDRKTG-VLTASRVFDREEQERFIFTVTARD 546
Query: 190 QGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLG 249
G+PPL S + VTVLD +D +PKFT+ H+ + ++ + ++ G I+ D D G
Sbjct: 547 NGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPK----YSTVGVITVTDADAG 602
Query: 250 INAPLQYSSTGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALA 307
N + S D+ V++ +G + + E S T +KAT P R + A
Sbjct: 603 ENKAVTLSILNDNDN-FVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTA 659
Score = 63.3 bits (147), Expect = 4e-09
Identities = 65/269 (24%), Positives = 110/269 (40%), Gaps = 15/269 (5%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEKIG 70
+SE+ G + T+S + S DI +L + + + LT R DREE+
Sbjct: 478 VSENNRRGLYLTTISATDEDSGKNADIVYQLGPNASFFDLDRKTGVLTASRVFDREEQ-- 535
Query: 71 PSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXX 130
V T V V V D NDN+P++ + VSE
Sbjct: 536 -ERFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVI 594
Query: 131 XXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQ 190
+D D G + A+ ++L + L + +I D E +++T ++ D
Sbjct: 595 TVTDADA-GENKAVTLSILNDNDNFVL---DPYSGVIKSNVSFDREQQSSYTFDVKATDG 650
Query: 191 GSPPLYSDTTLQVTVLDADDQNPKFTYEHYTA---LLPDDAEEGTFLTTSPGPISAADQD 247
G PP S + + V+D +D +P L+P A G+ + + A D D
Sbjct: 651 GQPPRSSTAKVTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPGSVV----AEVFAVDVD 706
Query: 248 LGINAPLQYS-STGDHKQLIVVNKDTGQV 275
G+NA L+Y+ +G++K L ++ TG +
Sbjct: 707 TGMNAELKYTIVSGNNKGLFRIDPVTGNI 735
Score = 55.2 bits (127), Expect = 1e-06
Identities = 94/477 (19%), Positives = 167/477 (35%), Gaps = 27/477 (5%)
Query: 57 LTLLRALDREEKIGPSNVYV-NVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAV 115
L + + LDRE+K + YV ++ + T S + V V DVNDN P ++ V
Sbjct: 204 LIVQQNLDREQK----DTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEV 259
Query: 116 RVSETXXXXXXXXXXXXSDRDQPGPHSALHY--AVLPGPHSEYLGFENELEPIIVVKKPL 173
+ E +D D G ++ + Y P ++ L N +I V++ L
Sbjct: 260 HIPENAPVGTSVIQLHATDAD-IGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQRSL 318
Query: 174 DFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDA--EEG 231
D E + + D S P + T+ VT D +D P + + + E
Sbjct: 319 DREETAIHKVTVLASDGSSTPARATVTINVT--DVNDNPPNIDLRYIISPINGTVYLSEK 376
Query: 232 TFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLI-AELDPSVT 290
+ T I+ +D+D +N + + + D + T L+ E +
Sbjct: 377 DPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYLLETSSLLDYEGTKEFS 436
Query: 291 IVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTL 350
+ A+ P A + F Q +VSE G L T+
Sbjct: 437 FKIVASDSGKPSLNQTALVRVKLEDENDNPPI-----FNQPVIELSVSENNRRGLYLTTI 491
Query: 351 TTVPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSIS 410
+ +++ + + SF D G + R D E + + V D+ +
Sbjct: 492 SATDEDSGKNADIVYQLGPNASFFD--LDRKTGVLTASRVFDREEQERFIFTVTARDNGT 549
Query: 411 ---NDTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGDAGT 467
A++ ++V D N+ P+F H ++F A G+
Sbjct: 550 PPLQSQAAVIVTVLDENDNSPKFTHNHFQF---FVSENLPKYSTVGVITVTDADAGENKA 606
Query: 468 LALSLAGQHARMFYINASGDLFLREEAIGNLNSSSLHLVATAIDSGIPPRQTSVPVT 524
+ LS+ + F ++ + + SS A D G PPR ++ VT
Sbjct: 607 VTLSILNDNDN-FVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVT 662
Score = 35.9 bits (79), Expect = 0.64
Identities = 26/98 (26%), Positives = 46/98 (46%), Gaps = 3/98 (3%)
Query: 9 FFISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEK 68
FF+SE+ P S +G ++V + + +TL + + P S + + DRE++
Sbjct: 579 FFVSENLPKYSTVGVITVTDADAGENKAVTLSILNDNDNFVLDPYSGVIKSNVSFDREQQ 638
Query: 69 IGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAP 106
S+ +V+ S V++ V DVNDN+P
Sbjct: 639 ---SSYTFDVKATDGGQPPRSSTAKVTINVMDVNDNSP 673
>AL603863-2|CAH72759.1| 1203|Homo sapiens protocadherin 9 protein.
Length = 1203
Score = 102 bits (245), Expect = 5e-21
Identities = 108/449 (24%), Positives = 170/449 (37%), Gaps = 31/449 (6%)
Query: 91 VIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLP 150
+I + + V D NDNAP + + + E +D D G + HY +L
Sbjct: 125 LIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDT-GFNGVQHYELLN 183
Query: 151 GPHSEYLGF----ENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVL 206
G L E E P ++V++ LD E + + +K++V+D G+P S LQVTV
Sbjct: 184 GQSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVS 243
Query: 207 DADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQY----SSTGDH 262
D +D P F +P++A G TS + A D D+G NA ++Y
Sbjct: 244 DVNDNRPVFKEGQVEVHIPENAPVG----TSVIQLHATDADIGSNAEIRYIFGAQVAPAT 299
Query: 263 KQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQV--DNPDRYALATLXXXXXXXXXXX 320
K+L +N TG + + LD T + K T + D A AT+
Sbjct: 300 KRLFALNNTTGLITVQR----SLDREETAIHKVTVLASDGSSTPARATVTINVTDVNDNP 355
Query: 321 XXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTV-PQNTEFRESPLQFYVSDRSFLDKFAI 379
T P + + L TV ++T+ + F + F K
Sbjct: 356 PNIDLRYIISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVY 415
Query: 380 NNAGEVILRRSLDYETTSNYFYQVMVTDS---ISNDTASINISVEDVNEWEPRFRHPQYE 436
+N + LDYE T + ++++ +DS N TA + + +ED N+ P F P E
Sbjct: 416 DNQYLLETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIE 475
Query: 437 FEXXXXXXXXXXXXXXXXXXXXVAHDGDAGTLA--LSLAGQHARMFYINASGDLFLREEA 494
A D D+G A + G +A F ++ +
Sbjct: 476 LSVSENNRRGLYLTTIS------ATDEDSGKNADIVYQLGPNASFFDLDRKTGVLTASRV 529
Query: 495 IGNLNSSSLHLVATAIDSGIPPRQTSVPV 523
TA D+G PP Q+ V
Sbjct: 530 FDREEQERFIFTVTARDNGTPPLQSQAAV 558
Score = 79.8 bits (188), Expect = 4e-14
Identities = 67/298 (22%), Positives = 122/298 (40%), Gaps = 10/298 (3%)
Query: 10 FISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEKI 69
++SE P+ + I ++V+ D D+ + E+ + N LL +
Sbjct: 372 YLSEKDPVNTKIALITVS-DKDTDVNGKVICFIEREVPFHLKAVYDNQYLLETSSLLDYE 430
Query: 70 GPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXX 129
G + + V V++ D NDN P + + VSE
Sbjct: 431 GTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTT 490
Query: 130 XXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQD 189
+D D G ++ + Y + GP++ + + + ++ + D E F + +D
Sbjct: 491 ISATDEDS-GKNADIVYQL--GPNASFFDLDRKTG-VLTASRVFDREEQERFIFTVTARD 546
Query: 190 QGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLG 249
G+PPL S + VTVLD +D +PKFT+ H+ + ++ + ++ G I+ D D G
Sbjct: 547 NGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPK----YSTVGVITVTDADAG 602
Query: 250 INAPLQYSSTGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALA 307
N + S D+ V++ +G + + E S T +KAT P R + A
Sbjct: 603 ENKAVTLSILNDNDN-FVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTA 659
Score = 63.3 bits (147), Expect = 4e-09
Identities = 65/269 (24%), Positives = 110/269 (40%), Gaps = 15/269 (5%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEKIG 70
+SE+ G + T+S + S DI +L + + + LT R DREE+
Sbjct: 478 VSENNRRGLYLTTISATDEDSGKNADIVYQLGPNASFFDLDRKTGVLTASRVFDREEQ-- 535
Query: 71 PSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXX 130
V T V V V D NDN+P++ + VSE
Sbjct: 536 -ERFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVI 594
Query: 131 XXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQ 190
+D D G + A+ ++L + L + +I D E +++T ++ D
Sbjct: 595 TVTDADA-GENKAVTLSILNDNDNFVL---DPYSGVIKSNVSFDREQQSSYTFDVKATDG 650
Query: 191 GSPPLYSDTTLQVTVLDADDQNPKFTYEHYTA---LLPDDAEEGTFLTTSPGPISAADQD 247
G PP S + + V+D +D +P L+P A G+ + + A D D
Sbjct: 651 GQPPRSSTAKVTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPGSVV----AEVFAVDVD 706
Query: 248 LGINAPLQYS-STGDHKQLIVVNKDTGQV 275
G+NA L+Y+ +G++K L ++ TG +
Sbjct: 707 TGMNAELKYTIVSGNNKGLFRIDPVTGNI 735
Score = 55.2 bits (127), Expect = 1e-06
Identities = 94/477 (19%), Positives = 167/477 (35%), Gaps = 27/477 (5%)
Query: 57 LTLLRALDREEKIGPSNVYV-NVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAV 115
L + + LDRE+K + YV ++ + T S + V V DVNDN P ++ V
Sbjct: 204 LIVQQNLDREQK----DTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEV 259
Query: 116 RVSETXXXXXXXXXXXXSDRDQPGPHSALHY--AVLPGPHSEYLGFENELEPIIVVKKPL 173
+ E +D D G ++ + Y P ++ L N +I V++ L
Sbjct: 260 HIPENAPVGTSVIQLHATDAD-IGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQRSL 318
Query: 174 DFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDA--EEG 231
D E + + D S P + T+ VT D +D P + + + E
Sbjct: 319 DREETAIHKVTVLASDGSSTPARATVTINVT--DVNDNPPNIDLRYIISPINGTVYLSEK 376
Query: 232 TFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLI-AELDPSVT 290
+ T I+ +D+D +N + + + D + T L+ E +
Sbjct: 377 DPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYLLETSSLLDYEGTKEFS 436
Query: 291 IVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTL 350
+ A+ P A + F Q +VSE G L T+
Sbjct: 437 FKIVASDSGKPSLNQTALVRVKLEDENDNPPI-----FNQPVIELSVSENNRRGLYLTTI 491
Query: 351 TTVPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSIS 410
+ +++ + + SF D G + R D E + + V D+ +
Sbjct: 492 SATDEDSGKNADIVYQLGPNASFFD--LDRKTGVLTASRVFDREEQERFIFTVTARDNGT 549
Query: 411 ---NDTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGDAGT 467
A++ ++V D N+ P+F H ++F A G+
Sbjct: 550 PPLQSQAAVIVTVLDENDNSPKFTHNHFQF---FVSENLPKYSTVGVITVTDADAGENKA 606
Query: 468 LALSLAGQHARMFYINASGDLFLREEAIGNLNSSSLHLVATAIDSGIPPRQTSVPVT 524
+ LS+ + F ++ + + SS A D G PPR ++ VT
Sbjct: 607 VTLSILNDNDN-FVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVT 662
Score = 35.9 bits (79), Expect = 0.64
Identities = 26/98 (26%), Positives = 46/98 (46%), Gaps = 3/98 (3%)
Query: 9 FFISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEK 68
FF+SE+ P S +G ++V + + +TL + + P S + + DRE++
Sbjct: 579 FFVSENLPKYSTVGVITVTDADAGENKAVTLSILNDNDNFVLDPYSGVIKSNVSFDREQQ 638
Query: 69 IGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAP 106
S+ +V+ S V++ V DVNDN+P
Sbjct: 639 ---SSYTFDVKATDGGQPPRSSTAKVTINVMDVNDNSP 673
>AL603863-1|CAH72758.1| 1032|Homo sapiens protocadherin 9 protein.
Length = 1032
Score = 102 bits (245), Expect = 5e-21
Identities = 108/449 (24%), Positives = 170/449 (37%), Gaps = 31/449 (6%)
Query: 91 VIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLP 150
+I + + V D NDNAP + + + E +D D G + HY +L
Sbjct: 125 LIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDT-GFNGVQHYELLN 183
Query: 151 GPHSEYLGF----ENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVL 206
G L E E P ++V++ LD E + + +K++V+D G+P S LQVTV
Sbjct: 184 GQSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVS 243
Query: 207 DADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQY----SSTGDH 262
D +D P F +P++A G TS + A D D+G NA ++Y
Sbjct: 244 DVNDNRPVFKEGQVEVHIPENAPVG----TSVIQLHATDADIGSNAEIRYIFGAQVAPAT 299
Query: 263 KQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQV--DNPDRYALATLXXXXXXXXXXX 320
K+L +N TG + + LD T + K T + D A AT+
Sbjct: 300 KRLFALNNTTGLITVQR----SLDREETAIHKVTVLASDGSSTPARATVTINVTDVNDNP 355
Query: 321 XXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTV-PQNTEFRESPLQFYVSDRSFLDKFAI 379
T P + + L TV ++T+ + F + F K
Sbjct: 356 PNIDLRYIISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVY 415
Query: 380 NNAGEVILRRSLDYETTSNYFYQVMVTDS---ISNDTASINISVEDVNEWEPRFRHPQYE 436
+N + LDYE T + ++++ +DS N TA + + +ED N+ P F P E
Sbjct: 416 DNQYLLETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIE 475
Query: 437 FEXXXXXXXXXXXXXXXXXXXXVAHDGDAGTLA--LSLAGQHARMFYINASGDLFLREEA 494
A D D+G A + G +A F ++ +
Sbjct: 476 LSVSENNRRGLYLTTIS------ATDEDSGKNADIVYQLGPNASFFDLDRKTGVLTASRV 529
Query: 495 IGNLNSSSLHLVATAIDSGIPPRQTSVPV 523
TA D+G PP Q+ V
Sbjct: 530 FDREEQERFIFTVTARDNGTPPLQSQAAV 558
Score = 79.8 bits (188), Expect = 4e-14
Identities = 67/298 (22%), Positives = 122/298 (40%), Gaps = 10/298 (3%)
Query: 10 FISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEKI 69
++SE P+ + I ++V+ D D+ + E+ + N LL +
Sbjct: 372 YLSEKDPVNTKIALITVS-DKDTDVNGKVICFIEREVPFHLKAVYDNQYLLETSSLLDYE 430
Query: 70 GPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXX 129
G + + V V++ D NDN P + + VSE
Sbjct: 431 GTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTT 490
Query: 130 XXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQD 189
+D D G ++ + Y + GP++ + + + ++ + D E F + +D
Sbjct: 491 ISATDEDS-GKNADIVYQL--GPNASFFDLDRKTG-VLTASRVFDREEQERFIFTVTARD 546
Query: 190 QGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLG 249
G+PPL S + VTVLD +D +PKFT+ H+ + ++ + ++ G I+ D D G
Sbjct: 547 NGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPK----YSTVGVITVTDADAG 602
Query: 250 INAPLQYSSTGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALA 307
N + S D+ V++ +G + + E S T +KAT P R + A
Sbjct: 603 ENKAVTLSILNDNDN-FVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTA 659
Score = 63.3 bits (147), Expect = 4e-09
Identities = 65/269 (24%), Positives = 110/269 (40%), Gaps = 15/269 (5%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEKIG 70
+SE+ G + T+S + S DI +L + + + LT R DREE+
Sbjct: 478 VSENNRRGLYLTTISATDEDSGKNADIVYQLGPNASFFDLDRKTGVLTASRVFDREEQ-- 535
Query: 71 PSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXX 130
V T V V V D NDN+P++ + VSE
Sbjct: 536 -ERFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVI 594
Query: 131 XXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQ 190
+D D G + A+ ++L + L + +I D E +++T ++ D
Sbjct: 595 TVTDADA-GENKAVTLSILNDNDNFVL---DPYSGVIKSNVSFDREQQSSYTFDVKATDG 650
Query: 191 GSPPLYSDTTLQVTVLDADDQNPKFTYEHYTA---LLPDDAEEGTFLTTSPGPISAADQD 247
G PP S + + V+D +D +P L+P A G+ + + A D D
Sbjct: 651 GQPPRSSTAKVTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPGSVV----AEVFAVDVD 706
Query: 248 LGINAPLQYS-STGDHKQLIVVNKDTGQV 275
G+NA L+Y+ +G++K L ++ TG +
Sbjct: 707 TGMNAELKYTIVSGNNKGLFRIDPVTGNI 735
Score = 55.2 bits (127), Expect = 1e-06
Identities = 94/477 (19%), Positives = 167/477 (35%), Gaps = 27/477 (5%)
Query: 57 LTLLRALDREEKIGPSNVYV-NVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAV 115
L + + LDRE+K + YV ++ + T S + V V DVNDN P ++ V
Sbjct: 204 LIVQQNLDREQK----DTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEV 259
Query: 116 RVSETXXXXXXXXXXXXSDRDQPGPHSALHY--AVLPGPHSEYLGFENELEPIIVVKKPL 173
+ E +D D G ++ + Y P ++ L N +I V++ L
Sbjct: 260 HIPENAPVGTSVIQLHATDAD-IGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQRSL 318
Query: 174 DFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDA--EEG 231
D E + + D S P + T+ VT D +D P + + + E
Sbjct: 319 DREETAIHKVTVLASDGSSTPARATVTINVT--DVNDNPPNIDLRYIISPINGTVYLSEK 376
Query: 232 TFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLI-AELDPSVT 290
+ T I+ +D+D +N + + + D + T L+ E +
Sbjct: 377 DPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYLLETSSLLDYEGTKEFS 436
Query: 291 IVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTL 350
+ A+ P A + F Q +VSE G L T+
Sbjct: 437 FKIVASDSGKPSLNQTALVRVKLEDENDNPPI-----FNQPVIELSVSENNRRGLYLTTI 491
Query: 351 TTVPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSIS 410
+ +++ + + SF D G + R D E + + V D+ +
Sbjct: 492 SATDEDSGKNADIVYQLGPNASFFD--LDRKTGVLTASRVFDREEQERFIFTVTARDNGT 549
Query: 411 ---NDTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGDAGT 467
A++ ++V D N+ P+F H ++F A G+
Sbjct: 550 PPLQSQAAVIVTVLDENDNSPKFTHNHFQF---FVSENLPKYSTVGVITVTDADAGENKA 606
Query: 468 LALSLAGQHARMFYINASGDLFLREEAIGNLNSSSLHLVATAIDSGIPPRQTSVPVT 524
+ LS+ + F ++ + + SS A D G PPR ++ VT
Sbjct: 607 VTLSILNDNDN-FVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVT 662
Score = 35.9 bits (79), Expect = 0.64
Identities = 26/98 (26%), Positives = 46/98 (46%), Gaps = 3/98 (3%)
Query: 9 FFISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEK 68
FF+SE+ P S +G ++V + + +TL + + P S + + DRE++
Sbjct: 579 FFVSENLPKYSTVGVITVTDADAGENKAVTLSILNDNDNFVLDPYSGVIKSNVSFDREQQ 638
Query: 69 IGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAP 106
S+ +V+ S V++ V DVNDN+P
Sbjct: 639 ---SSYTFDVKATDGGQPPRSSTAKVTINVMDVNDNSP 673
>AL355173-2|CAH72612.1| 1203|Homo sapiens protocadherin 9 protein.
Length = 1203
Score = 102 bits (245), Expect = 5e-21
Identities = 108/449 (24%), Positives = 170/449 (37%), Gaps = 31/449 (6%)
Query: 91 VIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLP 150
+I + + V D NDNAP + + + E +D D G + HY +L
Sbjct: 125 LIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDT-GFNGVQHYELLN 183
Query: 151 GPHSEYLGF----ENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVL 206
G L E E P ++V++ LD E + + +K++V+D G+P S LQVTV
Sbjct: 184 GQSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVS 243
Query: 207 DADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQY----SSTGDH 262
D +D P F +P++A G TS + A D D+G NA ++Y
Sbjct: 244 DVNDNRPVFKEGQVEVHIPENAPVG----TSVIQLHATDADIGSNAEIRYIFGAQVAPAT 299
Query: 263 KQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQV--DNPDRYALATLXXXXXXXXXXX 320
K+L +N TG + + LD T + K T + D A AT+
Sbjct: 300 KRLFALNNTTGLITVQR----SLDREETAIHKVTVLASDGSSTPARATVTINVTDVNDNP 355
Query: 321 XXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTV-PQNTEFRESPLQFYVSDRSFLDKFAI 379
T P + + L TV ++T+ + F + F K
Sbjct: 356 PNIDLRYIISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVY 415
Query: 380 NNAGEVILRRSLDYETTSNYFYQVMVTDS---ISNDTASINISVEDVNEWEPRFRHPQYE 436
+N + LDYE T + ++++ +DS N TA + + +ED N+ P F P E
Sbjct: 416 DNQYLLETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIE 475
Query: 437 FEXXXXXXXXXXXXXXXXXXXXVAHDGDAGTLA--LSLAGQHARMFYINASGDLFLREEA 494
A D D+G A + G +A F ++ +
Sbjct: 476 LSVSENNRRGLYLTTIS------ATDEDSGKNADIVYQLGPNASFFDLDRKTGVLTASRV 529
Query: 495 IGNLNSSSLHLVATAIDSGIPPRQTSVPV 523
TA D+G PP Q+ V
Sbjct: 530 FDREEQERFIFTVTARDNGTPPLQSQAAV 558
Score = 79.8 bits (188), Expect = 4e-14
Identities = 67/298 (22%), Positives = 122/298 (40%), Gaps = 10/298 (3%)
Query: 10 FISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEKI 69
++SE P+ + I ++V+ D D+ + E+ + N LL +
Sbjct: 372 YLSEKDPVNTKIALITVS-DKDTDVNGKVICFIEREVPFHLKAVYDNQYLLETSSLLDYE 430
Query: 70 GPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXX 129
G + + V V++ D NDN P + + VSE
Sbjct: 431 GTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTT 490
Query: 130 XXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQD 189
+D D G ++ + Y + GP++ + + + ++ + D E F + +D
Sbjct: 491 ISATDEDS-GKNADIVYQL--GPNASFFDLDRKTG-VLTASRVFDREEQERFIFTVTARD 546
Query: 190 QGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLG 249
G+PPL S + VTVLD +D +PKFT+ H+ + ++ + ++ G I+ D D G
Sbjct: 547 NGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPK----YSTVGVITVTDADAG 602
Query: 250 INAPLQYSSTGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALA 307
N + S D+ V++ +G + + E S T +KAT P R + A
Sbjct: 603 ENKAVTLSILNDNDN-FVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTA 659
Score = 63.3 bits (147), Expect = 4e-09
Identities = 65/269 (24%), Positives = 110/269 (40%), Gaps = 15/269 (5%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEKIG 70
+SE+ G + T+S + S DI +L + + + LT R DREE+
Sbjct: 478 VSENNRRGLYLTTISATDEDSGKNADIVYQLGPNASFFDLDRKTGVLTASRVFDREEQ-- 535
Query: 71 PSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXX 130
V T V V V D NDN+P++ + VSE
Sbjct: 536 -ERFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVI 594
Query: 131 XXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQ 190
+D D G + A+ ++L + L + +I D E +++T ++ D
Sbjct: 595 TVTDADA-GENKAVTLSILNDNDNFVL---DPYSGVIKSNVSFDREQQSSYTFDVKATDG 650
Query: 191 GSPPLYSDTTLQVTVLDADDQNPKFTYEHYTA---LLPDDAEEGTFLTTSPGPISAADQD 247
G PP S + + V+D +D +P L+P A G+ + + A D D
Sbjct: 651 GQPPRSSTAKVTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPGSVV----AEVFAVDVD 706
Query: 248 LGINAPLQYS-STGDHKQLIVVNKDTGQV 275
G+NA L+Y+ +G++K L ++ TG +
Sbjct: 707 TGMNAELKYTIVSGNNKGLFRIDPVTGNI 735
Score = 55.2 bits (127), Expect = 1e-06
Identities = 94/477 (19%), Positives = 167/477 (35%), Gaps = 27/477 (5%)
Query: 57 LTLLRALDREEKIGPSNVYV-NVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAV 115
L + + LDRE+K + YV ++ + T S + V V DVNDN P ++ V
Sbjct: 204 LIVQQNLDREQK----DTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEV 259
Query: 116 RVSETXXXXXXXXXXXXSDRDQPGPHSALHY--AVLPGPHSEYLGFENELEPIIVVKKPL 173
+ E +D D G ++ + Y P ++ L N +I V++ L
Sbjct: 260 HIPENAPVGTSVIQLHATDAD-IGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQRSL 318
Query: 174 DFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDA--EEG 231
D E + + D S P + T+ VT D +D P + + + E
Sbjct: 319 DREETAIHKVTVLASDGSSTPARATVTINVT--DVNDNPPNIDLRYIISPINGTVYLSEK 376
Query: 232 TFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLI-AELDPSVT 290
+ T I+ +D+D +N + + + D + T L+ E +
Sbjct: 377 DPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYLLETSSLLDYEGTKEFS 436
Query: 291 IVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTL 350
+ A+ P A + F Q +VSE G L T+
Sbjct: 437 FKIVASDSGKPSLNQTALVRVKLEDENDNPPI-----FNQPVIELSVSENNRRGLYLTTI 491
Query: 351 TTVPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSIS 410
+ +++ + + SF D G + R D E + + V D+ +
Sbjct: 492 SATDEDSGKNADIVYQLGPNASFFD--LDRKTGVLTASRVFDREEQERFIFTVTARDNGT 549
Query: 411 ---NDTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGDAGT 467
A++ ++V D N+ P+F H ++F A G+
Sbjct: 550 PPLQSQAAVIVTVLDENDNSPKFTHNHFQF---FVSENLPKYSTVGVITVTDADAGENKA 606
Query: 468 LALSLAGQHARMFYINASGDLFLREEAIGNLNSSSLHLVATAIDSGIPPRQTSVPVT 524
+ LS+ + F ++ + + SS A D G PPR ++ VT
Sbjct: 607 VTLSILNDNDN-FVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVT 662
Score = 35.9 bits (79), Expect = 0.64
Identities = 26/98 (26%), Positives = 46/98 (46%), Gaps = 3/98 (3%)
Query: 9 FFISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEK 68
FF+SE+ P S +G ++V + + +TL + + P S + + DRE++
Sbjct: 579 FFVSENLPKYSTVGVITVTDADAGENKAVTLSILNDNDNFVLDPYSGVIKSNVSFDREQQ 638
Query: 69 IGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAP 106
S+ +V+ S V++ V DVNDN+P
Sbjct: 639 ---SSYTFDVKATDGGQPPRSSTAKVTINVMDVNDNSP 673
>AL355173-1|CAM17290.1| 1237|Homo sapiens protocadherin 9 protein.
Length = 1237
Score = 102 bits (245), Expect = 5e-21
Identities = 108/449 (24%), Positives = 170/449 (37%), Gaps = 31/449 (6%)
Query: 91 VIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLP 150
+I + + V D NDNAP + + + E +D D G + HY +L
Sbjct: 125 LIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDT-GFNGVQHYELLN 183
Query: 151 GPHSEYLGF----ENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVL 206
G L E E P ++V++ LD E + + +K++V+D G+P S LQVTV
Sbjct: 184 GQSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVS 243
Query: 207 DADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQY----SSTGDH 262
D +D P F +P++A G TS + A D D+G NA ++Y
Sbjct: 244 DVNDNRPVFKEGQVEVHIPENAPVG----TSVIQLHATDADIGSNAEIRYIFGAQVAPAT 299
Query: 263 KQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQV--DNPDRYALATLXXXXXXXXXXX 320
K+L +N TG + + LD T + K T + D A AT+
Sbjct: 300 KRLFALNNTTGLITVQR----SLDREETAIHKVTVLASDGSSTPARATVTINVTDVNDNP 355
Query: 321 XXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTV-PQNTEFRESPLQFYVSDRSFLDKFAI 379
T P + + L TV ++T+ + F + F K
Sbjct: 356 PNIDLRYIISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVY 415
Query: 380 NNAGEVILRRSLDYETTSNYFYQVMVTDS---ISNDTASINISVEDVNEWEPRFRHPQYE 436
+N + LDYE T + ++++ +DS N TA + + +ED N+ P F P E
Sbjct: 416 DNQYLLETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIE 475
Query: 437 FEXXXXXXXXXXXXXXXXXXXXVAHDGDAGTLA--LSLAGQHARMFYINASGDLFLREEA 494
A D D+G A + G +A F ++ +
Sbjct: 476 LSVSENNRRGLYLTTIS------ATDEDSGKNADIVYQLGPNASFFDLDRKTGVLTASRV 529
Query: 495 IGNLNSSSLHLVATAIDSGIPPRQTSVPV 523
TA D+G PP Q+ V
Sbjct: 530 FDREEQERFIFTVTARDNGTPPLQSQAAV 558
Score = 79.8 bits (188), Expect = 4e-14
Identities = 67/298 (22%), Positives = 122/298 (40%), Gaps = 10/298 (3%)
Query: 10 FISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEKI 69
++SE P+ + I ++V+ D D+ + E+ + N LL +
Sbjct: 372 YLSEKDPVNTKIALITVS-DKDTDVNGKVICFIEREVPFHLKAVYDNQYLLETSSLLDYE 430
Query: 70 GPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXX 129
G + + V V++ D NDN P + + VSE
Sbjct: 431 GTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTT 490
Query: 130 XXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQD 189
+D D G ++ + Y + GP++ + + + ++ + D E F + +D
Sbjct: 491 ISATDEDS-GKNADIVYQL--GPNASFFDLDRKTG-VLTASRVFDREEQERFIFTVTARD 546
Query: 190 QGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLG 249
G+PPL S + VTVLD +D +PKFT+ H+ + ++ + ++ G I+ D D G
Sbjct: 547 NGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPK----YSTVGVITVTDADAG 602
Query: 250 INAPLQYSSTGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALA 307
N + S D+ V++ +G + + E S T +KAT P R + A
Sbjct: 603 ENKAVTLSILNDNDN-FVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTA 659
Score = 63.3 bits (147), Expect = 4e-09
Identities = 65/269 (24%), Positives = 110/269 (40%), Gaps = 15/269 (5%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEKIG 70
+SE+ G + T+S + S DI +L + + + LT R DREE+
Sbjct: 478 VSENNRRGLYLTTISATDEDSGKNADIVYQLGPNASFFDLDRKTGVLTASRVFDREEQ-- 535
Query: 71 PSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXX 130
V T V V V D NDN+P++ + VSE
Sbjct: 536 -ERFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVI 594
Query: 131 XXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQ 190
+D D G + A+ ++L + L + +I D E +++T ++ D
Sbjct: 595 TVTDADA-GENKAVTLSILNDNDNFVL---DPYSGVIKSNVSFDREQQSSYTFDVKATDG 650
Query: 191 GSPPLYSDTTLQVTVLDADDQNPKFTYEHYTA---LLPDDAEEGTFLTTSPGPISAADQD 247
G PP S + + V+D +D +P L+P A G+ + + A D D
Sbjct: 651 GQPPRSSTAKVTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPGSVV----AEVFAVDVD 706
Query: 248 LGINAPLQYS-STGDHKQLIVVNKDTGQV 275
G+NA L+Y+ +G++K L ++ TG +
Sbjct: 707 TGMNAELKYTIVSGNNKGLFRIDPVTGNI 735
Score = 55.2 bits (127), Expect = 1e-06
Identities = 94/477 (19%), Positives = 167/477 (35%), Gaps = 27/477 (5%)
Query: 57 LTLLRALDREEKIGPSNVYV-NVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAV 115
L + + LDRE+K + YV ++ + T S + V V DVNDN P ++ V
Sbjct: 204 LIVQQNLDREQK----DTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEV 259
Query: 116 RVSETXXXXXXXXXXXXSDRDQPGPHSALHY--AVLPGPHSEYLGFENELEPIIVVKKPL 173
+ E +D D G ++ + Y P ++ L N +I V++ L
Sbjct: 260 HIPENAPVGTSVIQLHATDAD-IGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQRSL 318
Query: 174 DFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDA--EEG 231
D E + + D S P + T+ VT D +D P + + + E
Sbjct: 319 DREETAIHKVTVLASDGSSTPARATVTINVT--DVNDNPPNIDLRYIISPINGTVYLSEK 376
Query: 232 TFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLI-AELDPSVT 290
+ T I+ +D+D +N + + + D + T L+ E +
Sbjct: 377 DPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYLLETSSLLDYEGTKEFS 436
Query: 291 IVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTL 350
+ A+ P A + F Q +VSE G L T+
Sbjct: 437 FKIVASDSGKPSLNQTALVRVKLEDENDNPPI-----FNQPVIELSVSENNRRGLYLTTI 491
Query: 351 TTVPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSIS 410
+ +++ + + SF D G + R D E + + V D+ +
Sbjct: 492 SATDEDSGKNADIVYQLGPNASFFD--LDRKTGVLTASRVFDREEQERFIFTVTARDNGT 549
Query: 411 ---NDTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGDAGT 467
A++ ++V D N+ P+F H ++F A G+
Sbjct: 550 PPLQSQAAVIVTVLDENDNSPKFTHNHFQF---FVSENLPKYSTVGVITVTDADAGENKA 606
Query: 468 LALSLAGQHARMFYINASGDLFLREEAIGNLNSSSLHLVATAIDSGIPPRQTSVPVT 524
+ LS+ + F ++ + + SS A D G PPR ++ VT
Sbjct: 607 VTLSILNDNDN-FVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVT 662
Score = 35.9 bits (79), Expect = 0.64
Identities = 26/98 (26%), Positives = 46/98 (46%), Gaps = 3/98 (3%)
Query: 9 FFISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEK 68
FF+SE+ P S +G ++V + + +TL + + P S + + DRE++
Sbjct: 579 FFVSENLPKYSTVGVITVTDADAGENKAVTLSILNDNDNFVLDPYSGVIKSNVSFDREQQ 638
Query: 69 IGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAP 106
S+ +V+ S V++ V DVNDN+P
Sbjct: 639 ---SSYTFDVKATDGGQPPRSSTAKVTINVMDVNDNSP 673
>AL138814-1|CAM13066.1| 1237|Homo sapiens protocadherin 9 protein.
Length = 1237
Score = 102 bits (245), Expect = 5e-21
Identities = 108/449 (24%), Positives = 170/449 (37%), Gaps = 31/449 (6%)
Query: 91 VIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLP 150
+I + + V D NDNAP + + + E +D D G + HY +L
Sbjct: 125 LIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDT-GFNGVQHYELLN 183
Query: 151 GPHSEYLGF----ENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVL 206
G L E E P ++V++ LD E + + +K++V+D G+P S LQVTV
Sbjct: 184 GQSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVS 243
Query: 207 DADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQY----SSTGDH 262
D +D P F +P++A G TS + A D D+G NA ++Y
Sbjct: 244 DVNDNRPVFKEGQVEVHIPENAPVG----TSVIQLHATDADIGSNAEIRYIFGAQVAPAT 299
Query: 263 KQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQV--DNPDRYALATLXXXXXXXXXXX 320
K+L +N TG + + LD T + K T + D A AT+
Sbjct: 300 KRLFALNNTTGLITVQR----SLDREETAIHKVTVLASDGSSTPARATVTINVTDVNDNP 355
Query: 321 XXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTV-PQNTEFRESPLQFYVSDRSFLDKFAI 379
T P + + L TV ++T+ + F + F K
Sbjct: 356 PNIDLRYIISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVY 415
Query: 380 NNAGEVILRRSLDYETTSNYFYQVMVTDS---ISNDTASINISVEDVNEWEPRFRHPQYE 436
+N + LDYE T + ++++ +DS N TA + + +ED N+ P F P E
Sbjct: 416 DNQYLLETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIE 475
Query: 437 FEXXXXXXXXXXXXXXXXXXXXVAHDGDAGTLA--LSLAGQHARMFYINASGDLFLREEA 494
A D D+G A + G +A F ++ +
Sbjct: 476 LSVSENNRRGLYLTTIS------ATDEDSGKNADIVYQLGPNASFFDLDRKTGVLTASRV 529
Query: 495 IGNLNSSSLHLVATAIDSGIPPRQTSVPV 523
TA D+G PP Q+ V
Sbjct: 530 FDREEQERFIFTVTARDNGTPPLQSQAAV 558
Score = 79.8 bits (188), Expect = 4e-14
Identities = 67/298 (22%), Positives = 122/298 (40%), Gaps = 10/298 (3%)
Query: 10 FISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEKI 69
++SE P+ + I ++V+ D D+ + E+ + N LL +
Sbjct: 372 YLSEKDPVNTKIALITVS-DKDTDVNGKVICFIEREVPFHLKAVYDNQYLLETSSLLDYE 430
Query: 70 GPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXX 129
G + + V V++ D NDN P + + VSE
Sbjct: 431 GTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTT 490
Query: 130 XXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQD 189
+D D G ++ + Y + GP++ + + + ++ + D E F + +D
Sbjct: 491 ISATDEDS-GKNADIVYQL--GPNASFFDLDRKTG-VLTASRVFDREEQERFIFTVTARD 546
Query: 190 QGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLG 249
G+PPL S + VTVLD +D +PKFT+ H+ + ++ + ++ G I+ D D G
Sbjct: 547 NGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPK----YSTVGVITVTDADAG 602
Query: 250 INAPLQYSSTGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALA 307
N + S D+ V++ +G + + E S T +KAT P R + A
Sbjct: 603 ENKAVTLSILNDNDN-FVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTA 659
Score = 63.3 bits (147), Expect = 4e-09
Identities = 65/269 (24%), Positives = 110/269 (40%), Gaps = 15/269 (5%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEKIG 70
+SE+ G + T+S + S DI +L + + + LT R DREE+
Sbjct: 478 VSENNRRGLYLTTISATDEDSGKNADIVYQLGPNASFFDLDRKTGVLTASRVFDREEQ-- 535
Query: 71 PSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXX 130
V T V V V D NDN+P++ + VSE
Sbjct: 536 -ERFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVI 594
Query: 131 XXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQ 190
+D D G + A+ ++L + L + +I D E +++T ++ D
Sbjct: 595 TVTDADA-GENKAVTLSILNDNDNFVL---DPYSGVIKSNVSFDREQQSSYTFDVKATDG 650
Query: 191 GSPPLYSDTTLQVTVLDADDQNPKFTYEHYTA---LLPDDAEEGTFLTTSPGPISAADQD 247
G PP S + + V+D +D +P L+P A G+ + + A D D
Sbjct: 651 GQPPRSSTAKVTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPGSVV----AEVFAVDVD 706
Query: 248 LGINAPLQYS-STGDHKQLIVVNKDTGQV 275
G+NA L+Y+ +G++K L ++ TG +
Sbjct: 707 TGMNAELKYTIVSGNNKGLFRIDPVTGNI 735
Score = 55.2 bits (127), Expect = 1e-06
Identities = 94/477 (19%), Positives = 167/477 (35%), Gaps = 27/477 (5%)
Query: 57 LTLLRALDREEKIGPSNVYV-NVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAV 115
L + + LDRE+K + YV ++ + T S + V V DVNDN P ++ V
Sbjct: 204 LIVQQNLDREQK----DTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEV 259
Query: 116 RVSETXXXXXXXXXXXXSDRDQPGPHSALHY--AVLPGPHSEYLGFENELEPIIVVKKPL 173
+ E +D D G ++ + Y P ++ L N +I V++ L
Sbjct: 260 HIPENAPVGTSVIQLHATDAD-IGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQRSL 318
Query: 174 DFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDA--EEG 231
D E + + D S P + T+ VT D +D P + + + E
Sbjct: 319 DREETAIHKVTVLASDGSSTPARATVTINVT--DVNDNPPNIDLRYIISPINGTVYLSEK 376
Query: 232 TFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLI-AELDPSVT 290
+ T I+ +D+D +N + + + D + T L+ E +
Sbjct: 377 DPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYLLETSSLLDYEGTKEFS 436
Query: 291 IVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTL 350
+ A+ P A + F Q +VSE G L T+
Sbjct: 437 FKIVASDSGKPSLNQTALVRVKLEDENDNPPI-----FNQPVIELSVSENNRRGLYLTTI 491
Query: 351 TTVPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSIS 410
+ +++ + + SF D G + R D E + + V D+ +
Sbjct: 492 SATDEDSGKNADIVYQLGPNASFFD--LDRKTGVLTASRVFDREEQERFIFTVTARDNGT 549
Query: 411 ---NDTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGDAGT 467
A++ ++V D N+ P+F H ++F A G+
Sbjct: 550 PPLQSQAAVIVTVLDENDNSPKFTHNHFQF---FVSENLPKYSTVGVITVTDADAGENKA 606
Query: 468 LALSLAGQHARMFYINASGDLFLREEAIGNLNSSSLHLVATAIDSGIPPRQTSVPVT 524
+ LS+ + F ++ + + SS A D G PPR ++ VT
Sbjct: 607 VTLSILNDNDN-FVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVT 662
Score = 35.9 bits (79), Expect = 0.64
Identities = 26/98 (26%), Positives = 46/98 (46%), Gaps = 3/98 (3%)
Query: 9 FFISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEK 68
FF+SE+ P S +G ++V + + +TL + + P S + + DRE++
Sbjct: 579 FFVSENLPKYSTVGVITVTDADAGENKAVTLSILNDNDNFVLDPYSGVIKSNVSFDREQQ 638
Query: 69 IGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAP 106
S+ +V+ S V++ V DVNDN+P
Sbjct: 639 ---SSYTFDVKATDGGQPPRSSTAKVTINVMDVNDNSP 673
>AL136999-2|CAI12502.1| 1203|Homo sapiens protocadherin 9 protein.
Length = 1203
Score = 102 bits (245), Expect = 5e-21
Identities = 108/449 (24%), Positives = 170/449 (37%), Gaps = 31/449 (6%)
Query: 91 VIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLP 150
+I + + V D NDNAP + + + E +D D G + HY +L
Sbjct: 125 LIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDT-GFNGVQHYELLN 183
Query: 151 GPHSEYLGF----ENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVL 206
G L E E P ++V++ LD E + + +K++V+D G+P S LQVTV
Sbjct: 184 GQSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVS 243
Query: 207 DADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQY----SSTGDH 262
D +D P F +P++A G TS + A D D+G NA ++Y
Sbjct: 244 DVNDNRPVFKEGQVEVHIPENAPVG----TSVIQLHATDADIGSNAEIRYIFGAQVAPAT 299
Query: 263 KQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQV--DNPDRYALATLXXXXXXXXXXX 320
K+L +N TG + + LD T + K T + D A AT+
Sbjct: 300 KRLFALNNTTGLITVQR----SLDREETAIHKVTVLASDGSSTPARATVTINVTDVNDNP 355
Query: 321 XXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTV-PQNTEFRESPLQFYVSDRSFLDKFAI 379
T P + + L TV ++T+ + F + F K
Sbjct: 356 PNIDLRYIISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVY 415
Query: 380 NNAGEVILRRSLDYETTSNYFYQVMVTDS---ISNDTASINISVEDVNEWEPRFRHPQYE 436
+N + LDYE T + ++++ +DS N TA + + +ED N+ P F P E
Sbjct: 416 DNQYLLETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIE 475
Query: 437 FEXXXXXXXXXXXXXXXXXXXXVAHDGDAGTLA--LSLAGQHARMFYINASGDLFLREEA 494
A D D+G A + G +A F ++ +
Sbjct: 476 LSVSENNRRGLYLTTIS------ATDEDSGKNADIVYQLGPNASFFDLDRKTGVLTASRV 529
Query: 495 IGNLNSSSLHLVATAIDSGIPPRQTSVPV 523
TA D+G PP Q+ V
Sbjct: 530 FDREEQERFIFTVTARDNGTPPLQSQAAV 558
Score = 79.8 bits (188), Expect = 4e-14
Identities = 67/298 (22%), Positives = 122/298 (40%), Gaps = 10/298 (3%)
Query: 10 FISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEKI 69
++SE P+ + I ++V+ D D+ + E+ + N LL +
Sbjct: 372 YLSEKDPVNTKIALITVS-DKDTDVNGKVICFIEREVPFHLKAVYDNQYLLETSSLLDYE 430
Query: 70 GPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXX 129
G + + V V++ D NDN P + + VSE
Sbjct: 431 GTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTT 490
Query: 130 XXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQD 189
+D D G ++ + Y + GP++ + + + ++ + D E F + +D
Sbjct: 491 ISATDEDS-GKNADIVYQL--GPNASFFDLDRKTG-VLTASRVFDREEQERFIFTVTARD 546
Query: 190 QGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLG 249
G+PPL S + VTVLD +D +PKFT+ H+ + ++ + ++ G I+ D D G
Sbjct: 547 NGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPK----YSTVGVITVTDADAG 602
Query: 250 INAPLQYSSTGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALA 307
N + S D+ V++ +G + + E S T +KAT P R + A
Sbjct: 603 ENKAVTLSILNDNDN-FVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTA 659
Score = 63.3 bits (147), Expect = 4e-09
Identities = 65/269 (24%), Positives = 110/269 (40%), Gaps = 15/269 (5%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEKIG 70
+SE+ G + T+S + S DI +L + + + LT R DREE+
Sbjct: 478 VSENNRRGLYLTTISATDEDSGKNADIVYQLGPNASFFDLDRKTGVLTASRVFDREEQ-- 535
Query: 71 PSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXX 130
V T V V V D NDN+P++ + VSE
Sbjct: 536 -ERFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVI 594
Query: 131 XXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQ 190
+D D G + A+ ++L + L + +I D E +++T ++ D
Sbjct: 595 TVTDADA-GENKAVTLSILNDNDNFVL---DPYSGVIKSNVSFDREQQSSYTFDVKATDG 650
Query: 191 GSPPLYSDTTLQVTVLDADDQNPKFTYEHYTA---LLPDDAEEGTFLTTSPGPISAADQD 247
G PP S + + V+D +D +P L+P A G+ + + A D D
Sbjct: 651 GQPPRSSTAKVTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPGSVV----AEVFAVDVD 706
Query: 248 LGINAPLQYS-STGDHKQLIVVNKDTGQV 275
G+NA L+Y+ +G++K L ++ TG +
Sbjct: 707 TGMNAELKYTIVSGNNKGLFRIDPVTGNI 735
Score = 55.2 bits (127), Expect = 1e-06
Identities = 94/477 (19%), Positives = 167/477 (35%), Gaps = 27/477 (5%)
Query: 57 LTLLRALDREEKIGPSNVYV-NVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAV 115
L + + LDRE+K + YV ++ + T S + V V DVNDN P ++ V
Sbjct: 204 LIVQQNLDREQK----DTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEV 259
Query: 116 RVSETXXXXXXXXXXXXSDRDQPGPHSALHY--AVLPGPHSEYLGFENELEPIIVVKKPL 173
+ E +D D G ++ + Y P ++ L N +I V++ L
Sbjct: 260 HIPENAPVGTSVIQLHATDAD-IGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQRSL 318
Query: 174 DFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDA--EEG 231
D E + + D S P + T+ VT D +D P + + + E
Sbjct: 319 DREETAIHKVTVLASDGSSTPARATVTINVT--DVNDNPPNIDLRYIISPINGTVYLSEK 376
Query: 232 TFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLI-AELDPSVT 290
+ T I+ +D+D +N + + + D + T L+ E +
Sbjct: 377 DPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYLLETSSLLDYEGTKEFS 436
Query: 291 IVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTL 350
+ A+ P A + F Q +VSE G L T+
Sbjct: 437 FKIVASDSGKPSLNQTALVRVKLEDENDNPPI-----FNQPVIELSVSENNRRGLYLTTI 491
Query: 351 TTVPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSIS 410
+ +++ + + SF D G + R D E + + V D+ +
Sbjct: 492 SATDEDSGKNADIVYQLGPNASFFD--LDRKTGVLTASRVFDREEQERFIFTVTARDNGT 549
Query: 411 ---NDTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGDAGT 467
A++ ++V D N+ P+F H ++F A G+
Sbjct: 550 PPLQSQAAVIVTVLDENDNSPKFTHNHFQF---FVSENLPKYSTVGVITVTDADAGENKA 606
Query: 468 LALSLAGQHARMFYINASGDLFLREEAIGNLNSSSLHLVATAIDSGIPPRQTSVPVT 524
+ LS+ + F ++ + + SS A D G PPR ++ VT
Sbjct: 607 VTLSILNDNDN-FVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVT 662
Score = 35.9 bits (79), Expect = 0.64
Identities = 26/98 (26%), Positives = 46/98 (46%), Gaps = 3/98 (3%)
Query: 9 FFISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEK 68
FF+SE+ P S +G ++V + + +TL + + P S + + DRE++
Sbjct: 579 FFVSENLPKYSTVGVITVTDADAGENKAVTLSILNDNDNFVLDPYSGVIKSNVSFDREQQ 638
Query: 69 IGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAP 106
S+ +V+ S V++ V DVNDN+P
Sbjct: 639 ---SSYTFDVKATDGGQPPRSSTAKVTINVMDVNDNSP 673
>AL136999-1|CAM13771.1| 1237|Homo sapiens protocadherin 9 protein.
Length = 1237
Score = 102 bits (245), Expect = 5e-21
Identities = 108/449 (24%), Positives = 170/449 (37%), Gaps = 31/449 (6%)
Query: 91 VIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLP 150
+I + + V D NDNAP + + + E +D D G + HY +L
Sbjct: 125 LIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDT-GFNGVQHYELLN 183
Query: 151 GPHSEYLGF----ENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVL 206
G L E E P ++V++ LD E + + +K++V+D G+P S LQVTV
Sbjct: 184 GQSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVS 243
Query: 207 DADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQY----SSTGDH 262
D +D P F +P++A G TS + A D D+G NA ++Y
Sbjct: 244 DVNDNRPVFKEGQVEVHIPENAPVG----TSVIQLHATDADIGSNAEIRYIFGAQVAPAT 299
Query: 263 KQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQV--DNPDRYALATLXXXXXXXXXXX 320
K+L +N TG + + LD T + K T + D A AT+
Sbjct: 300 KRLFALNNTTGLITVQR----SLDREETAIHKVTVLASDGSSTPARATVTINVTDVNDNP 355
Query: 321 XXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTV-PQNTEFRESPLQFYVSDRSFLDKFAI 379
T P + + L TV ++T+ + F + F K
Sbjct: 356 PNIDLRYIISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVY 415
Query: 380 NNAGEVILRRSLDYETTSNYFYQVMVTDS---ISNDTASINISVEDVNEWEPRFRHPQYE 436
+N + LDYE T + ++++ +DS N TA + + +ED N+ P F P E
Sbjct: 416 DNQYLLETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIE 475
Query: 437 FEXXXXXXXXXXXXXXXXXXXXVAHDGDAGTLA--LSLAGQHARMFYINASGDLFLREEA 494
A D D+G A + G +A F ++ +
Sbjct: 476 LSVSENNRRGLYLTTIS------ATDEDSGKNADIVYQLGPNASFFDLDRKTGVLTASRV 529
Query: 495 IGNLNSSSLHLVATAIDSGIPPRQTSVPV 523
TA D+G PP Q+ V
Sbjct: 530 FDREEQERFIFTVTARDNGTPPLQSQAAV 558
Score = 79.8 bits (188), Expect = 4e-14
Identities = 67/298 (22%), Positives = 122/298 (40%), Gaps = 10/298 (3%)
Query: 10 FISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEKI 69
++SE P+ + I ++V+ D D+ + E+ + N LL +
Sbjct: 372 YLSEKDPVNTKIALITVS-DKDTDVNGKVICFIEREVPFHLKAVYDNQYLLETSSLLDYE 430
Query: 70 GPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXX 129
G + + V V++ D NDN P + + VSE
Sbjct: 431 GTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTT 490
Query: 130 XXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQD 189
+D D G ++ + Y + GP++ + + + ++ + D E F + +D
Sbjct: 491 ISATDEDS-GKNADIVYQL--GPNASFFDLDRKTG-VLTASRVFDREEQERFIFTVTARD 546
Query: 190 QGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLG 249
G+PPL S + VTVLD +D +PKFT+ H+ + ++ + ++ G I+ D D G
Sbjct: 547 NGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPK----YSTVGVITVTDADAG 602
Query: 250 INAPLQYSSTGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALA 307
N + S D+ V++ +G + + E S T +KAT P R + A
Sbjct: 603 ENKAVTLSILNDNDN-FVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTA 659
Score = 63.3 bits (147), Expect = 4e-09
Identities = 65/269 (24%), Positives = 110/269 (40%), Gaps = 15/269 (5%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEKIG 70
+SE+ G + T+S + S DI +L + + + LT R DREE+
Sbjct: 478 VSENNRRGLYLTTISATDEDSGKNADIVYQLGPNASFFDLDRKTGVLTASRVFDREEQ-- 535
Query: 71 PSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXX 130
V T V V V D NDN+P++ + VSE
Sbjct: 536 -ERFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVI 594
Query: 131 XXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQ 190
+D D G + A+ ++L + L + +I D E +++T ++ D
Sbjct: 595 TVTDADA-GENKAVTLSILNDNDNFVL---DPYSGVIKSNVSFDREQQSSYTFDVKATDG 650
Query: 191 GSPPLYSDTTLQVTVLDADDQNPKFTYEHYTA---LLPDDAEEGTFLTTSPGPISAADQD 247
G PP S + + V+D +D +P L+P A G+ + + A D D
Sbjct: 651 GQPPRSSTAKVTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPGSVV----AEVFAVDVD 706
Query: 248 LGINAPLQYS-STGDHKQLIVVNKDTGQV 275
G+NA L+Y+ +G++K L ++ TG +
Sbjct: 707 TGMNAELKYTIVSGNNKGLFRIDPVTGNI 735
Score = 55.2 bits (127), Expect = 1e-06
Identities = 94/477 (19%), Positives = 167/477 (35%), Gaps = 27/477 (5%)
Query: 57 LTLLRALDREEKIGPSNVYV-NVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAV 115
L + + LDRE+K + YV ++ + T S + V V DVNDN P ++ V
Sbjct: 204 LIVQQNLDREQK----DTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEV 259
Query: 116 RVSETXXXXXXXXXXXXSDRDQPGPHSALHY--AVLPGPHSEYLGFENELEPIIVVKKPL 173
+ E +D D G ++ + Y P ++ L N +I V++ L
Sbjct: 260 HIPENAPVGTSVIQLHATDAD-IGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQRSL 318
Query: 174 DFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDA--EEG 231
D E + + D S P + T+ VT D +D P + + + E
Sbjct: 319 DREETAIHKVTVLASDGSSTPARATVTINVT--DVNDNPPNIDLRYIISPINGTVYLSEK 376
Query: 232 TFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLI-AELDPSVT 290
+ T I+ +D+D +N + + + D + T L+ E +
Sbjct: 377 DPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYLLETSSLLDYEGTKEFS 436
Query: 291 IVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTL 350
+ A+ P A + F Q +VSE G L T+
Sbjct: 437 FKIVASDSGKPSLNQTALVRVKLEDENDNPPI-----FNQPVIELSVSENNRRGLYLTTI 491
Query: 351 TTVPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSIS 410
+ +++ + + SF D G + R D E + + V D+ +
Sbjct: 492 SATDEDSGKNADIVYQLGPNASFFD--LDRKTGVLTASRVFDREEQERFIFTVTARDNGT 549
Query: 411 ---NDTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGDAGT 467
A++ ++V D N+ P+F H ++F A G+
Sbjct: 550 PPLQSQAAVIVTVLDENDNSPKFTHNHFQF---FVSENLPKYSTVGVITVTDADAGENKA 606
Query: 468 LALSLAGQHARMFYINASGDLFLREEAIGNLNSSSLHLVATAIDSGIPPRQTSVPVT 524
+ LS+ + F ++ + + SS A D G PPR ++ VT
Sbjct: 607 VTLSILNDNDN-FVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVT 662
Score = 35.9 bits (79), Expect = 0.64
Identities = 26/98 (26%), Positives = 46/98 (46%), Gaps = 3/98 (3%)
Query: 9 FFISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEK 68
FF+SE+ P S +G ++V + + +TL + + P S + + DRE++
Sbjct: 579 FFVSENLPKYSTVGVITVTDADAGENKAVTLSILNDNDNFVLDPYSGVIKSNVSFDREQQ 638
Query: 69 IGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAP 106
S+ +V+ S V++ V DVNDN+P
Sbjct: 639 ---SSYTFDVKATDGGQPPRSSTAKVTINVMDVNDNSP 673
>AF169692-1|AAF89689.2| 1203|Homo sapiens protocadherin-9 protein.
Length = 1203
Score = 102 bits (245), Expect = 5e-21
Identities = 108/449 (24%), Positives = 170/449 (37%), Gaps = 31/449 (6%)
Query: 91 VIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLP 150
+I + + V D NDNAP + + + E +D D G + HY +L
Sbjct: 125 LIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDT-GFNGVQHYELLN 183
Query: 151 GPHSEYLGF----ENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVL 206
G L E E P ++V++ LD E + + +K++V+D G+P S LQVTV
Sbjct: 184 GQSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVS 243
Query: 207 DADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQY----SSTGDH 262
D +D P F +P++A G TS + A D D+G NA ++Y
Sbjct: 244 DVNDNRPVFKEGQVEVHIPENAPVG----TSVIQLHATDADIGSNAEIRYIFGAQVAPAT 299
Query: 263 KQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQV--DNPDRYALATLXXXXXXXXXXX 320
K+L +N TG + + LD T + K T + D A AT+
Sbjct: 300 KRLFALNNTTGLITVQR----SLDREETAIHKVTVLASDGSSTPARATVTINVTDVNDNP 355
Query: 321 XXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTV-PQNTEFRESPLQFYVSDRSFLDKFAI 379
T P + + L TV ++T+ + F + F K
Sbjct: 356 PNIDLRYIISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVY 415
Query: 380 NNAGEVILRRSLDYETTSNYFYQVMVTDS---ISNDTASINISVEDVNEWEPRFRHPQYE 436
+N + LDYE T + ++++ +DS N TA + + +ED N+ P F P E
Sbjct: 416 DNQYLLETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIE 475
Query: 437 FEXXXXXXXXXXXXXXXXXXXXVAHDGDAGTLA--LSLAGQHARMFYINASGDLFLREEA 494
A D D+G A + G +A F ++ +
Sbjct: 476 LSVSENNRRGLYLTTIS------ATDEDSGKNADIVYQLGPNASFFDLDRKTGVLTASRV 529
Query: 495 IGNLNSSSLHLVATAIDSGIPPRQTSVPV 523
TA D+G PP Q+ V
Sbjct: 530 FDREEQERFIFTVTARDNGTPPLQSQAAV 558
Score = 79.8 bits (188), Expect = 4e-14
Identities = 67/298 (22%), Positives = 122/298 (40%), Gaps = 10/298 (3%)
Query: 10 FISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEKI 69
++SE P+ + I ++V+ D D+ + E+ + N LL +
Sbjct: 372 YLSEKDPVNTKIALITVS-DKDTDVNGKVICFIEREVPFHLKAVYDNQYLLETSSLLDYE 430
Query: 70 GPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXX 129
G + + V V++ D NDN P + + VSE
Sbjct: 431 GTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTT 490
Query: 130 XXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQD 189
+D D G ++ + Y + GP++ + + + ++ + D E F + +D
Sbjct: 491 ISATDEDS-GKNADIVYQL--GPNASFFDLDRKTG-VLTASRVFDREEQERFIFTVTARD 546
Query: 190 QGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLG 249
G+PPL S + VTVLD +D +PKFT+ H+ + ++ + ++ G I+ D D G
Sbjct: 547 NGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPK----YSTVGVITVTDADAG 602
Query: 250 INAPLQYSSTGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALA 307
N + S D+ V++ +G + + E S T +KAT P R + A
Sbjct: 603 ENKAVTLSILNDNDN-FVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTA 659
Score = 63.3 bits (147), Expect = 4e-09
Identities = 65/269 (24%), Positives = 110/269 (40%), Gaps = 15/269 (5%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEKIG 70
+SE+ G + T+S + S DI +L + + + LT R DREE+
Sbjct: 478 VSENNRRGLYLTTISATDEDSGKNADIVYQLGPNASFFDLDRKTGVLTASRVFDREEQ-- 535
Query: 71 PSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXX 130
V T V V V D NDN+P++ + VSE
Sbjct: 536 -ERFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVI 594
Query: 131 XXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQ 190
+D D G + A+ ++L + L + +I D E +++T ++ D
Sbjct: 595 TVTDADA-GENKAVTLSILNDNDNFVL---DPYSGVIKSNVSFDREQQSSYTFDVKATDG 650
Query: 191 GSPPLYSDTTLQVTVLDADDQNPKFTYEHYTA---LLPDDAEEGTFLTTSPGPISAADQD 247
G PP S + + V+D +D +P L+P A G+ + + A D D
Sbjct: 651 GQPPRSSTAKVTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPGSVV----AEVFAVDVD 706
Query: 248 LGINAPLQYS-STGDHKQLIVVNKDTGQV 275
G+NA L+Y+ +G++K L ++ TG +
Sbjct: 707 TGMNAELKYTIVSGNNKGLFRIDPVTGNI 735
Score = 55.2 bits (127), Expect = 1e-06
Identities = 94/477 (19%), Positives = 167/477 (35%), Gaps = 27/477 (5%)
Query: 57 LTLLRALDREEKIGPSNVYV-NVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAV 115
L + + LDRE+K + YV ++ + T S + V V DVNDN P ++ V
Sbjct: 204 LIVQQNLDREQK----DTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEV 259
Query: 116 RVSETXXXXXXXXXXXXSDRDQPGPHSALHY--AVLPGPHSEYLGFENELEPIIVVKKPL 173
+ E +D D G ++ + Y P ++ L N +I V++ L
Sbjct: 260 HIPENAPVGTSVIQLHATDAD-IGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQRSL 318
Query: 174 DFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDA--EEG 231
D E + + D S P + T+ VT D +D P + + + E
Sbjct: 319 DREETAIHKVTVLASDGSSTPARATVTINVT--DVNDNPPNIDLRYIISPINGTVYLSEK 376
Query: 232 TFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLI-AELDPSVT 290
+ T I+ +D+D +N + + + D + T L+ E +
Sbjct: 377 DPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYLLETSSLLDYEGTKEFS 436
Query: 291 IVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTL 350
+ A+ P A + F Q +VSE G L T+
Sbjct: 437 FKIVASDSGKPSLNQTALVRVKLEDENDNPPI-----FNQPVIELSVSENNRRGLYLTTI 491
Query: 351 TTVPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSIS 410
+ +++ + + SF D G + R D E + + V D+ +
Sbjct: 492 SATDEDSGKNADIVYQLGPNASFFD--LDRKTGVLTASRVFDREEQERFIFTVTARDNGT 549
Query: 411 ---NDTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGDAGT 467
A++ ++V D N+ P+F H ++F A G+
Sbjct: 550 PPLQSQAAVIVTVLDENDNSPKFTHNHFQF---FVSENLPKYSTVGVITVTDADAGENKA 606
Query: 468 LALSLAGQHARMFYINASGDLFLREEAIGNLNSSSLHLVATAIDSGIPPRQTSVPVT 524
+ LS+ + F ++ + + SS A D G PPR ++ VT
Sbjct: 607 VTLSILNDNDN-FVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVT 662
Score = 35.9 bits (79), Expect = 0.64
Identities = 26/98 (26%), Positives = 46/98 (46%), Gaps = 3/98 (3%)
Query: 9 FFISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEK 68
FF+SE+ P S +G ++V + + +TL + + P S + + DRE++
Sbjct: 579 FFVSENLPKYSTVGVITVTDADAGENKAVTLSILNDNDNFVLDPYSGVIKSNVSFDREQQ 638
Query: 69 IGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAP 106
S+ +V+ S V++ V DVNDN+P
Sbjct: 639 ---SSYTFDVKATDGGQPPRSSTAKVTINVMDVNDNSP 673
>BC036062-1|AAH36062.1| 776|Homo sapiens protocadherin beta 16
protein.
Length = 776
Score = 101 bits (242), Expect = 1e-20
Identities = 104/445 (23%), Positives = 183/445 (41%), Gaps = 27/445 (6%)
Query: 3 GGAVESFFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAA--VGIVPGSKNLTL 59
G + S+ + E+T GS + L + G ++ R+ +G + + + +L +
Sbjct: 27 GAELGSYSVVEETERGSFVANLGKDLGLGLTEMSTRKARIISQGNKQHLQLKAQTGDLLI 86
Query: 60 LRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSE 119
LDREE GP+ + + +P + +RV D+ND++P + +++ E
Sbjct: 87 NEKLDREELCGPTEPCI--LHFQVLMENPLEIFQAELRVIDINDHSPMFTEKEMILKIPE 144
Query: 120 TXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFE---NELEPIIVVKKPLDFE 176
D D G ++ +Y + P H L E P +V+ K LD E
Sbjct: 145 NSPLGTEFPLNHALDLDV-GSNNVQNYKISPSSHFRVLIHEFRDGRKYPELVLDKELDRE 203
Query: 177 TVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTT 236
+ L D GSPP +++ V+D +D P+F Y +P+++ G+ + T
Sbjct: 204 EEPQLRLTLTALDGGSPPRSGTAQVRIEVVDINDNAPEFEQPIYKVQIPENSPLGSLVAT 263
Query: 237 SPGPISAADQDLGINAPLQYS---STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVL 293
+SA D D G N + Y+ + D + + VN TG+V KQ+ E+ S + +
Sbjct: 264 ----VSARDLDGGANGKISYTLFQPSEDISKTLEVNPMTGEVRLRKQVDFEMVTSYEVRI 319
Query: 294 KATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTV 353
KAT D TL Q T ++ ++E SP V+ +
Sbjct: 320 KAT--DGGGLSGKCTLLLQVVDVNDNPP-----QVTMSALTSPIAEN-SPEIVVAVFSVS 371
Query: 354 PQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSIS--- 410
++ + D FL K ++ N ++ R+LD E + Y + VTD +
Sbjct: 372 DPDSGNNGKTISSIQEDLPFLLKPSVKNFYTLVTERALDREARAEYNITLTVTDMGTPRL 431
Query: 411 NDTASINISVEDVNEWEPRFRHPQY 435
+I + + DVN+ P F Y
Sbjct: 432 KTEHNITVQISDVNDNAPTFTQTSY 456
Score = 80.2 bits (189), Expect = 3e-14
Identities = 88/314 (28%), Positives = 136/314 (43%), Gaps = 26/314 (8%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLL---RALDREE 67
I+E++P ++ SV+ S + G +QE + + P KN L RALDRE
Sbjct: 356 IAENSP-EIVVAVFSVSDPDSGNNGKTISSIQEDLPFL-LKPSVKNFYTLVTERALDREA 413
Query: 68 KIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXX 127
+ + + + T ++V++ DVNDNAP + Y + V E
Sbjct: 414 R---AEYNITLTVTDMGTPRLKTEHNITVQISDVNDNAPTFTQTSYTLFVRENNSPALHI 470
Query: 128 XXXXXSDRDQPGPHSALHYAVLP--GPHSEYLGFE--NELEPIIVVKKPLDFETVNNFTI 183
+DRD G ++ + Y++LP PH N + + LD+E + F
Sbjct: 471 GSVSATDRDS-GTNAQVTYSLLPPQDPHLPLASLVSINADNGHLFALRSLDYEALQAFEF 529
Query: 184 KLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTY------EHYTALLPDDAEEGTFLTTS 237
++ D+GSP L + ++V VLDA+D +P Y T L+P AE G +T
Sbjct: 530 RVGATDRGSPALSREALVRVLVLDANDNSPLVLYPLQNGSAPCTELVPRAAEPGYLVT-- 587
Query: 238 PGPISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPS-VTIVLKA 295
+ A D D G NA L Y L V G+V T +L++E D + +V+
Sbjct: 588 --KVVAVDGDSGQNAWLSYQLLKATEPGLFGVWAHNGEV-RTARLLSERDAAKQRLVVLV 644
Query: 296 TQVDNPDRYALATL 309
P R A ATL
Sbjct: 645 KDNGEPPRSATATL 658
Score = 79.4 bits (187), Expect = 5e-14
Identities = 115/480 (23%), Positives = 181/480 (37%), Gaps = 34/480 (7%)
Query: 57 LTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVR 116
L L + LDREE+ + + + + S V + V D+NDNAP++E Y V+
Sbjct: 194 LVLDKELDREEE---PQLRLTLTALDGGSPPRSGTAQVRIEVVDINDNAPEFEQPIYKVQ 250
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPI---IVVKKPL 173
+ E D D G + + Y + SE + E+ P+ + ++K +
Sbjct: 251 IPENSPLGSLVATVSARDLDG-GANGKISYTLFQP--SEDISKTLEVNPMTGEVRLRKQV 307
Query: 174 DFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTF 233
DFE V ++ ++++ D G L TL + V+D +D P+ T T+ + +++ E
Sbjct: 308 DFEMVTSYEVRIKATDGGG--LSGKCTLLLQVVDVNDNPPQVTMSALTSPIAENSPEIVV 365
Query: 234 LTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVN-KDTGQVAATKQLIAELDPSVTIV 292
S +D D G N S D L+ + K+ + + L E I
Sbjct: 366 AV-----FSVSDPDSGNNGKTISSIQEDLPFLLKPSVKNFYTLVTERALDREARAEYNIT 420
Query: 293 LKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASP----GSVLL 348
L T + P L T FTQ Y+ V E SP GSV
Sbjct: 421 LTVTDMGTP---RLKT--EHNITVQISDVNDNAPTFTQTSYTLFVRENNSPALHIGSVSA 475
Query: 349 TLTTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTD 407
T N + S L +IN + G + RSLDYE + ++V TD
Sbjct: 476 TDRDSGTNAQVTYSLLPPQDPHLPLASLVSINADNGHLFALRSLDYEALQAFEFRVGATD 535
Query: 408 SIS---NDTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGD 464
S + A + + V D N+ P +P VA DGD
Sbjct: 536 RGSPALSREALVRVLVLDANDNSPLVLYPLQNGSAPCTELVPRAAEPGYLVTKVVAVDGD 595
Query: 465 AGTLA-LS---LAGQHARMFYINASGDLFLREEAIGNLNSSSLHLVATAIDSGIPPRQTS 520
+G A LS L +F + A + +++ LV D+G PPR +
Sbjct: 596 SGQNAWLSYQLLKATEPGLFGVWAHNGEVRTARLLSERDAAKQRLVVLVKDNGEPPRSAT 655
>BC113460-1|AAI13461.1| 813|Homo sapiens protocadherin gamma
subfamily A, 5 protein.
Length = 813
Score = 101 bits (241), Expect = 2e-20
Identities = 126/541 (23%), Positives = 222/541 (41%), Gaps = 49/541 (9%)
Query: 9 FFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAA--VGIVPGSKNLTLLRALDR 65
+ + E+ GS +G ++ + G ++L + +R+ +G + P S +L +DR
Sbjct: 33 YSMPEELDKGSFVGNIAKDLGLEPQELAERGVRIVSRGRTQLFALNPRSGSLVTAGRIDR 92
Query: 66 EEKIGPSNVYV---NVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXX 122
EE S + V N+ + + + V V + D+NDN P++ V+V+E
Sbjct: 93 EELCAQSPLCVVNFNILVENKMK-----IYGVEVEIIDINDNFPRFRDEELKVKVNENAA 147
Query: 123 XXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEY---LGFENELEPIIVVKKPLDFETVN 179
D D G +S Y + H G + + P +V+++PLD E
Sbjct: 148 AGTRLVLPFARDADV-GVNSLRSYQLSSNLHFSLDVVSGTDGQKYPELVLEQPLDREKET 206
Query: 180 NFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPG 239
+ L D G P L T ++VTVLDA+D P FT Y+ +P++ GT L
Sbjct: 207 VHDLLLTALDGGDPVLSGTTHIRVTVLDANDNAPLFTPSEYSVSVPENIPVGTRLLM--- 263
Query: 240 PISAADQDLGINAPLQYSSTGDHKQL---IVVNKDTGQVAATKQLIAELDPSVTIVLKAT 296
++A D D GIN L YS + +++ ++ + G+++ + L + + S +++
Sbjct: 264 -LTATDPDEGINGKLTYSFRNEEEKISETFQLDSNLGEISTLQSL--DYEESRFYLMEVV 320
Query: 297 QVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQN 356
D A A + T +++SE PG+V + L +V
Sbjct: 321 AQDGGALVASAKVVVTVQDVNDNAPEVILTSLT-----SSISEDCLPGTV-IALFSVHDG 374
Query: 357 TEFRESPLQFYV-SDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSIS---ND 412
+ + + F + +++N ++ R LD E TS+Y + V D + +
Sbjct: 375 DSGENGEIACSIPRNLPFKLEKSVDNYYHLLTTRDLDREETSDYNITLTVMDHGTPPLST 434
Query: 413 TASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGDAG---TLA 469
+ I + V DVN+ P F Y AHD D+G +
Sbjct: 435 ESHIPLKVADVNDNPPNFPQASY------STSVTENNPRGVSIFSVTAHDPDSGDNARVT 488
Query: 470 LSLAG---QHARM-FYINASGD--LFLREEAIGNLNSSSLHLVATAIDSGIPPRQTSVPV 523
SLA Q A + Y++ + D + + L L TA DSG PP ++V +
Sbjct: 489 YSLAEDTFQGAPLSSYVSINSDTGVLYALRSFDYEQLRDLQLWVTASDSGNPPLSSNVSL 548
Query: 524 T 524
+
Sbjct: 549 S 549
Score = 79.8 bits (188), Expect = 4e-14
Identities = 76/287 (26%), Positives = 120/287 (41%), Gaps = 24/287 (8%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEK--GAAVGIVPGSKNLTLLRALDREEK 68
ISED G++I SV+ S + G+I + V +L R LDREE
Sbjct: 356 ISEDCLPGTVIALFSVHDGDSGENGEIACSIPRNLPFKLEKSVDNYYHLLTTRDLDREET 415
Query: 69 IGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXX 128
S+ + + T S + ++V DVNDN P + A Y+ V+E
Sbjct: 416 ---SDYNITLTVMDHGTPPLSTESHIPLKVADVNDNPPNFPQASYSTSVTENNPRGVSIF 472
Query: 129 XXXXSDRDQPGPHSALHYAVLP-----GPHSEYLGFENELEPIIVVKKPLDFETVNNFTI 183
D D G ++ + Y++ P S Y+ ++ ++ + D+E + + +
Sbjct: 473 SVTAHDPDS-GDNARVTYSLAEDTFQGAPLSSYVSINSDTG-VLYALRSFDYEQLRDLQL 530
Query: 184 KLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFL---TTSPG- 239
+ D G+PPL S+ +L + VLD +D P+ Y LP D G L + PG
Sbjct: 531 WVTASDSGNPPLSSNVSLSLFVLDQNDNTPEILY----PALPTDGSTGVELAPRSAEPGY 586
Query: 240 ---PISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLI 282
+ A D+D G NA L Y L V TG+V + L+
Sbjct: 587 LVTKVVAVDKDSGQNAWLSYRLLKASEPGLFAVGLHTGEVRTARALL 633
>BC104926-1|AAI04927.1| 813|Homo sapiens protocadherin gamma
subfamily A, 5 protein.
Length = 813
Score = 101 bits (241), Expect = 2e-20
Identities = 126/541 (23%), Positives = 222/541 (41%), Gaps = 49/541 (9%)
Query: 9 FFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAA--VGIVPGSKNLTLLRALDR 65
+ + E+ GS +G ++ + G ++L + +R+ +G + P S +L +DR
Sbjct: 33 YSMPEELDKGSFVGNIAKDLGLEPQELAERGVRIVSRGRTQLFALNPRSGSLVTAGRIDR 92
Query: 66 EEKIGPSNVYV---NVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXX 122
EE S + V N+ + + + V V + D+NDN P++ V+V+E
Sbjct: 93 EELCAQSPLCVVNFNILVENKMK-----IYGVEVEIIDINDNFPRFRDEELKVKVNENAA 147
Query: 123 XXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEY---LGFENELEPIIVVKKPLDFETVN 179
D D G +S Y + H G + + P +V+++PLD E
Sbjct: 148 AGTRLVLPFARDADV-GVNSLRSYQLSSNLHFSLDVVSGTDGQKYPELVLEQPLDREKET 206
Query: 180 NFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPG 239
+ L D G P L T ++VTVLDA+D P FT Y+ +P++ GT L
Sbjct: 207 VHDLLLTALDGGDPVLSGTTHIRVTVLDANDNAPLFTPSEYSVSVPENIPVGTRLLM--- 263
Query: 240 PISAADQDLGINAPLQYSSTGDHKQL---IVVNKDTGQVAATKQLIAELDPSVTIVLKAT 296
++A D D GIN L YS + +++ ++ + G+++ + L + + S +++
Sbjct: 264 -LTATDPDEGINGKLTYSFRNEEEKISETFQLDSNLGEISTLQSL--DYEESRFYLMEVV 320
Query: 297 QVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQN 356
D A A + T +++SE PG+V + L +V
Sbjct: 321 AQDGGALVASAKVVVTVQDVNDNAPEVILTSLT-----SSISEDCLPGTV-IALFSVHDG 374
Query: 357 TEFRESPLQFYV-SDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSIS---ND 412
+ + + F + +++N ++ R LD E TS+Y + V D + +
Sbjct: 375 DSGENGEIACSIPRNLPFKLEKSVDNYYHLLTTRDLDREETSDYNITLTVMDHGTPPLST 434
Query: 413 TASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGDAG---TLA 469
+ I + V DVN+ P F Y AHD D+G +
Sbjct: 435 ESHIPLKVADVNDNPPNFPQASY------STSVTENNPRGVSIFSVTAHDPDSGDNARVT 488
Query: 470 LSLAG---QHARM-FYINASGD--LFLREEAIGNLNSSSLHLVATAIDSGIPPRQTSVPV 523
SLA Q A + Y++ + D + + L L TA DSG PP ++V +
Sbjct: 489 YSLAEDTFQGAPLSSYVSINSDTGVLYALRSFDYEQLRDLQLWVTASDSGNPPLSSNVSL 548
Query: 524 T 524
+
Sbjct: 549 S 549
Score = 79.8 bits (188), Expect = 4e-14
Identities = 76/287 (26%), Positives = 120/287 (41%), Gaps = 24/287 (8%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEK--GAAVGIVPGSKNLTLLRALDREEK 68
ISED G++I SV+ S + G+I + V +L R LDREE
Sbjct: 356 ISEDCLPGTVIALFSVHDGDSGENGEIACSIPRNLPFKLEKSVDNYYHLLTTRDLDREET 415
Query: 69 IGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXX 128
S+ + + T S + ++V DVNDN P + A Y+ V+E
Sbjct: 416 ---SDYNITLTVMDHGTPPLSTESHIPLKVADVNDNPPNFPQASYSTSVTENNPRGVSIF 472
Query: 129 XXXXSDRDQPGPHSALHYAVLP-----GPHSEYLGFENELEPIIVVKKPLDFETVNNFTI 183
D D G ++ + Y++ P S Y+ ++ ++ + D+E + + +
Sbjct: 473 SVTAHDPDS-GDNARVTYSLAEDTFQGAPLSSYVSINSDTG-VLYALRSFDYEQLRDLQL 530
Query: 184 KLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFL---TTSPG- 239
+ D G+PPL S+ +L + VLD +D P+ Y LP D G L + PG
Sbjct: 531 WVTASDSGNPPLSSNVSLSLFVLDQNDNTPEILY----PALPTDGSTGVELAPRSAEPGY 586
Query: 240 ---PISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLI 282
+ A D+D G NA L Y L V TG+V + L+
Sbjct: 587 LVTKVVAVDKDSGQNAWLSYRLLKASEPGLFAVGLHTGEVRTARALL 633
>AF152512-1|AAD43772.1| 813|Homo sapiens protocadherin gamma A5
short form protein protein.
Length = 813
Score = 101 bits (241), Expect = 2e-20
Identities = 126/541 (23%), Positives = 222/541 (41%), Gaps = 49/541 (9%)
Query: 9 FFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAA--VGIVPGSKNLTLLRALDR 65
+ + E+ GS +G ++ + G ++L + +R+ +G + P S +L +DR
Sbjct: 33 YSMPEELDKGSFVGNIAKDLGLEPQELAERGVRIVSRGRTQLFALNPRSGSLVTAGRIDR 92
Query: 66 EEKIGPSNVYV---NVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXX 122
EE S + V N+ + + + V V + D+NDN P++ V+V+E
Sbjct: 93 EELCAQSPLCVVNFNILVENKMK-----IYGVEVEIIDINDNFPRFRDEELKVKVNENAA 147
Query: 123 XXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEY---LGFENELEPIIVVKKPLDFETVN 179
D D G +S Y + H G + + P +V+++PLD E
Sbjct: 148 AGTRLVLPFARDADV-GVNSLRSYQLSSNLHFSLDVVSGTDGQKYPELVLEQPLDREKET 206
Query: 180 NFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPG 239
+ L D G P L T ++VTVLDA+D P FT Y+ +P++ GT L
Sbjct: 207 VHDLLLTALDGGDPVLSGTTHIRVTVLDANDNAPLFTPSEYSVSVPENIPVGTRLLM--- 263
Query: 240 PISAADQDLGINAPLQYSSTGDHKQL---IVVNKDTGQVAATKQLIAELDPSVTIVLKAT 296
++A D D GIN L YS + +++ ++ + G+++ + L + + S +++
Sbjct: 264 -LTATDPDEGINGKLTYSFRNEEEKISETFQLDSNLGEISTLQSL--DYEESRFYLMEVV 320
Query: 297 QVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQN 356
D A A + T +++SE PG+V + L +V
Sbjct: 321 AQDGGALVASAKVVVTVQDVNDNAPEVILTSLT-----SSISEDCLPGTV-IALFSVHDG 374
Query: 357 TEFRESPLQFYV-SDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSIS---ND 412
+ + + F + +++N ++ R LD E TS+Y + V D + +
Sbjct: 375 DSGENGEIACSIPRNLPFKLEKSVDNYYHLLTTRDLDREETSDYNITLTVMDHGTPPLST 434
Query: 413 TASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGDAG---TLA 469
+ I + V DVN+ P F Y AHD D+G +
Sbjct: 435 ESHIPLKVADVNDNPPNFPQASY------STSVTENNPRGVSIFSVTAHDPDSGDNARVT 488
Query: 470 LSLAG---QHARM-FYINASGD--LFLREEAIGNLNSSSLHLVATAIDSGIPPRQTSVPV 523
SLA Q A + Y++ + D + + L L TA DSG PP ++V +
Sbjct: 489 YSLAEDTFQGAPLSSYVSINSDTGVLYALRSFDYEQLRDLQLWVTASDSGNPPLSSNVSL 548
Query: 524 T 524
+
Sbjct: 549 S 549
Score = 79.8 bits (188), Expect = 4e-14
Identities = 76/287 (26%), Positives = 120/287 (41%), Gaps = 24/287 (8%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEK--GAAVGIVPGSKNLTLLRALDREEK 68
ISED G++I SV+ S + G+I + V +L R LDREE
Sbjct: 356 ISEDCLPGTVIALFSVHDGDSGENGEIACSIPRNLPFKLEKSVDNYYHLLTTRDLDREET 415
Query: 69 IGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXX 128
S+ + + T S + ++V DVNDN P + A Y+ V+E
Sbjct: 416 ---SDYNITLTVMDHGTPPLSTESHIPLKVADVNDNPPNFPQASYSTSVTENNPRGVSIF 472
Query: 129 XXXXSDRDQPGPHSALHYAVLP-----GPHSEYLGFENELEPIIVVKKPLDFETVNNFTI 183
D D G ++ + Y++ P S Y+ ++ ++ + D+E + + +
Sbjct: 473 SVTAHDPDS-GDNARVTYSLAEDTFQGAPLSSYVSINSDTG-VLYALRSFDYEQLRDLQL 530
Query: 184 KLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFL---TTSPG- 239
+ D G+PPL S+ +L + VLD +D P+ Y LP D G L + PG
Sbjct: 531 WVTASDSGNPPLSSNVSLSLFVLDQNDNTPEILY----PALPTDGSTGVELAPRSAEPGY 586
Query: 240 ---PISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLI 282
+ A D+D G NA L Y L V TG+V + L+
Sbjct: 587 LVTKVVAVDKDSGQNAWLSYRLLKASEPGLFAVGLHTGEVRTARALL 633
>AF152325-1|AAD43719.1| 931|Homo sapiens protocadherin gamma A5
protein.
Length = 931
Score = 101 bits (241), Expect = 2e-20
Identities = 126/541 (23%), Positives = 222/541 (41%), Gaps = 49/541 (9%)
Query: 9 FFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAA--VGIVPGSKNLTLLRALDR 65
+ + E+ GS +G ++ + G ++L + +R+ +G + P S +L +DR
Sbjct: 33 YSMPEELDKGSFVGNIAKDLGLEPQELAERGVRIVSRGRTQLFALNPRSGSLVTAGRIDR 92
Query: 66 EEKIGPSNVYV---NVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXX 122
EE S + V N+ + + + V V + D+NDN P++ V+V+E
Sbjct: 93 EELCAQSPLCVVNFNILVENKMK-----IYGVEVEIIDINDNFPRFRDEELKVKVNENAA 147
Query: 123 XXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEY---LGFENELEPIIVVKKPLDFETVN 179
D D G +S Y + H G + + P +V+++PLD E
Sbjct: 148 AGTRLVLPFARDADV-GVNSLRSYQLSSNLHFSLDVVSGTDGQKYPELVLEQPLDREKET 206
Query: 180 NFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPG 239
+ L D G P L T ++VTVLDA+D P FT Y+ +P++ GT L
Sbjct: 207 VHDLLLTALDGGDPVLSGTTHIRVTVLDANDNAPLFTPSEYSVSVPENIPVGTRLLM--- 263
Query: 240 PISAADQDLGINAPLQYSSTGDHKQL---IVVNKDTGQVAATKQLIAELDPSVTIVLKAT 296
++A D D GIN L YS + +++ ++ + G+++ + L + + S +++
Sbjct: 264 -LTATDPDEGINGKLTYSFRNEEEKISETFQLDSNLGEISTLQSL--DYEESRFYLMEVV 320
Query: 297 QVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQN 356
D A A + T +++SE PG+V + L +V
Sbjct: 321 AQDGGALVASAKVVVTVQDVNDNAPEVILTSLT-----SSISEDCLPGTV-IALFSVHDG 374
Query: 357 TEFRESPLQFYV-SDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSIS---ND 412
+ + + F + +++N ++ R LD E TS+Y + V D + +
Sbjct: 375 DSGENGEIACSIPRNLPFKLEKSVDNYYHLLTTRDLDREETSDYNITLTVMDHGTPPLST 434
Query: 413 TASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGDAG---TLA 469
+ I + V DVN+ P F Y AHD D+G +
Sbjct: 435 ESHIPLKVADVNDNPPNFPQASY------STSVTENNPRGVSIFSVTAHDPDSGDNARVT 488
Query: 470 LSLAG---QHARM-FYINASGD--LFLREEAIGNLNSSSLHLVATAIDSGIPPRQTSVPV 523
SLA Q A + Y++ + D + + L L TA DSG PP ++V +
Sbjct: 489 YSLAEDTFQGAPLSSYVSINSDTGVLYALRSFDYEQLRDLQLWVTASDSGNPPLSSNVSL 548
Query: 524 T 524
+
Sbjct: 549 S 549
Score = 79.8 bits (188), Expect = 4e-14
Identities = 76/287 (26%), Positives = 120/287 (41%), Gaps = 24/287 (8%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEK--GAAVGIVPGSKNLTLLRALDREEK 68
ISED G++I SV+ S + G+I + V +L R LDREE
Sbjct: 356 ISEDCLPGTVIALFSVHDGDSGENGEIACSIPRNLPFKLEKSVDNYYHLLTTRDLDREET 415
Query: 69 IGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXX 128
S+ + + T S + ++V DVNDN P + A Y+ V+E
Sbjct: 416 ---SDYNITLTVMDHGTPPLSTESHIPLKVADVNDNPPNFPQASYSTSVTENNPRGVSIF 472
Query: 129 XXXXSDRDQPGPHSALHYAVLP-----GPHSEYLGFENELEPIIVVKKPLDFETVNNFTI 183
D D G ++ + Y++ P S Y+ ++ ++ + D+E + + +
Sbjct: 473 SVTAHDPDS-GDNARVTYSLAEDTFQGAPLSSYVSINSDTG-VLYALRSFDYEQLRDLQL 530
Query: 184 KLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFL---TTSPG- 239
+ D G+PPL S+ +L + VLD +D P+ Y LP D G L + PG
Sbjct: 531 WVTASDSGNPPLSSNVSLSLFVLDQNDNTPEILY----PALPTDGSTGVELAPRSAEPGY 586
Query: 240 ---PISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLI 282
+ A D+D G NA L Y L V TG+V + L+
Sbjct: 587 LVTKVVAVDKDSGQNAWLSYRLLKASEPGLFAVGLHTGEVRTARALL 633
>BC112084-1|AAI12085.1| 823|Homo sapiens protocadherin gamma
subfamily A, 1 protein.
Length = 823
Score = 100 bits (240), Expect = 2e-20
Identities = 105/443 (23%), Positives = 183/443 (41%), Gaps = 34/443 (7%)
Query: 9 FFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAA--VGIVPGSKNLTLLRALDR 65
+ + E+T GS +G ++ + G ++L D +R+ +G + P S +L R +DR
Sbjct: 33 YSVPEETDKGSFVGNIAKDLGLQPQELADGGVRIVSRGRMPLFALNPRSGSLITARRIDR 92
Query: 66 EEKIG---PSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXX 122
EE P V N+ + D + PV V + D+NDN PQ++ +++E
Sbjct: 93 EELCAQSMPCLVSFNILVE-----DKMKLFPVEVEIIDINDNTPQFQLEELEFKMNEITT 147
Query: 123 XXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEY---LGFENELEPIIVVKKPLDFETVN 179
D D G +S Y + PH G + P +V++ PLD E
Sbjct: 148 PGTRISLPFGQDLDV-GMNSLQSYQLSSNPHFSLDVQQGADGPQHPEMVLQSPLDREEEA 206
Query: 180 NFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPG 239
+ L D G P + + V+DA+D P FT Y +P++ GT L
Sbjct: 207 VHHLILTASDGGEPVRSGTLRIYIQVVDANDNPPAFTQAQYHINVPENVPLGTQLLM--- 263
Query: 240 PISAADQDLGINAPLQYS-STGDHK--QLIVVNKDTGQVAATKQLIAELDPSVTIVLKAT 296
++A D D G N + YS DH+ Q+ ++ TG+++ + L E + +
Sbjct: 264 -VNATDPDEGANGEVTYSFHNVDHRVAQIFRLDSYTGEISNKEPLDFE-----EYKMYSM 317
Query: 297 QVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQN 356
+V D L + + T +T V E PG+++ ++ Q+
Sbjct: 318 EVQAQDGAGL--MAKVKVLIKVLDVNDNAPEVTITSVTTAVPENFPPGTIIALISVHDQD 375
Query: 357 TEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTD----SISND 412
+ F + F + ++N ++ R+LD E S Y + D ++S +
Sbjct: 376 SGDNGYTTCFIPGNLPFKLEKLVDNYYRLVTERTLDRELISGYNITITAIDQGTPALSTE 435
Query: 413 TASINISVEDVNEWEPRFRHPQY 435
T I++ V D+N+ P F Y
Sbjct: 436 T-HISLLVTDINDNSPVFHQDSY 457
Score = 75.8 bits (178), Expect = 6e-13
Identities = 78/313 (24%), Positives = 124/313 (39%), Gaps = 22/313 (7%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEK--GAAVGIVPGSKNLTLLRALDREEK 68
+ E+ P G+II +SV+ S D G T + +V L R LDRE
Sbjct: 356 VPENFPPGTIIALISVHDQDSGDNGYTTCFIPGNLPFKLEKLVDNYYRLVTERTLDRELI 415
Query: 69 IGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXX 128
G + + + + T S +S+ V D+NDN+P + Y+ + E
Sbjct: 416 SGYN---ITITAIDQGTPALSTETHISLLVTDINDNSPVFHQDSYSAYIPENNPRGASIF 472
Query: 129 XXXXSDRDQPG----PHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIK 184
D D +S + + P S YL ++ ++ + D+E + +K
Sbjct: 473 SVRAHDLDSNENAQITYSLIEDTIQGAPLSAYLSINSDTG-VLYALRSFDYEQFRDMQLK 531
Query: 185 LRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTF---LTTSPG-- 239
+ +D G PPL S+ +L + +LD +D P+ Y LP D G L+ PG
Sbjct: 532 VMARDSGDPPLSSNVSLSLFLLDQNDNAPEILY----PALPTDGSTGVELAPLSAEPGYL 587
Query: 240 --PISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKAT 296
+ A D+D G NA L Y L V TG+V + L+ ++V+
Sbjct: 588 VTKVVAVDRDSGQNAWLSYRLLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQ 647
Query: 297 QVDNPDRYALATL 309
P A TL
Sbjct: 648 DHGQPPLSATVTL 660
Score = 64.1 bits (149), Expect = 2e-09
Identities = 53/216 (24%), Positives = 92/216 (42%), Gaps = 12/216 (5%)
Query: 92 IPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPG 151
+ V ++V DVNDNAP+ V E D+D + +PG
Sbjct: 331 VKVLIKVLDVNDNAPEVTITSVTTAVPENFPPGTIIALISVHDQDSGD--NGYTTCFIPG 388
Query: 152 PHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQ 211
L + +V ++ LD E ++ + I + DQG+P L ++T + + V D +D
Sbjct: 389 NLPFKLEKLVDNYYRLVTERTLDRELISGYNITITAIDQGTPALSTETHISLLVTDINDN 448
Query: 212 NPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQ------L 265
+P F + Y+A +P++ G + + + A D D NA + YS D Q
Sbjct: 449 SPVFHQDSYSAYIPENNPRGASIFS----VRAHDLDSNENAQITYSLIEDTIQGAPLSAY 504
Query: 266 IVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNP 301
+ +N DTG + A + E + + + A +P
Sbjct: 505 LSINSDTGVLYALRSFDYEQFRDMQLKVMARDSGDP 540
>BC112082-1|AAI12083.1| 823|Homo sapiens protocadherin gamma
subfamily A, 1, isoform 2 precursor protein.
Length = 823
Score = 100 bits (240), Expect = 2e-20
Identities = 105/443 (23%), Positives = 183/443 (41%), Gaps = 34/443 (7%)
Query: 9 FFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAA--VGIVPGSKNLTLLRALDR 65
+ + E+T GS +G ++ + G ++L D +R+ +G + P S +L R +DR
Sbjct: 33 YSVPEETDKGSFVGNIAKDLGLQPQELADGGVRIVSRGRMPLFALNPRSGSLITARRIDR 92
Query: 66 EEKIG---PSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXX 122
EE P V N+ + D + PV V + D+NDN PQ++ +++E
Sbjct: 93 EELCAQSMPCLVSFNILVE-----DKMKLFPVEVEIIDINDNTPQFQLEELEFKMNEITT 147
Query: 123 XXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEY---LGFENELEPIIVVKKPLDFETVN 179
D D G +S Y + PH G + P +V++ PLD E
Sbjct: 148 PGTRISLPFGQDLDV-GMNSLQSYQLSSNPHFSLDVQQGADGPQHPEMVLQSPLDREEEA 206
Query: 180 NFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPG 239
+ L D G P + + V+DA+D P FT Y +P++ GT L
Sbjct: 207 VHHLILTASDGGEPVRSGTLRIYIQVVDANDNPPAFTQAQYHINVPENVPLGTQLLM--- 263
Query: 240 PISAADQDLGINAPLQYS-STGDHK--QLIVVNKDTGQVAATKQLIAELDPSVTIVLKAT 296
++A D D G N + YS DH+ Q+ ++ TG+++ + L E + +
Sbjct: 264 -VNATDPDEGANGEVTYSFHNVDHRVAQIFRLDSYTGEISNKEPLDFE-----EYKMYSM 317
Query: 297 QVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQN 356
+V D L + + T +T V E PG+++ ++ Q+
Sbjct: 318 EVQAQDGAGL--MAKVKVLIKVLDVNDNAPEVTITSVTTAVPENFPPGTIIALISVHDQD 375
Query: 357 TEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTD----SISND 412
+ F + F + ++N ++ R+LD E S Y + D ++S +
Sbjct: 376 SGDNGYTTCFIPGNLPFKLEKLVDNYYRLVTERTLDRELISGYNITITAIDQGTPALSTE 435
Query: 413 TASINISVEDVNEWEPRFRHPQY 435
T I++ V D+N+ P F Y
Sbjct: 436 T-HISLLVTDINDNSPVFHQDSY 457
Score = 75.8 bits (178), Expect = 6e-13
Identities = 78/313 (24%), Positives = 124/313 (39%), Gaps = 22/313 (7%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEK--GAAVGIVPGSKNLTLLRALDREEK 68
+ E+ P G+II +SV+ S D G T + +V L R LDRE
Sbjct: 356 VPENFPPGTIIALISVHDQDSGDNGYTTCFIPGNLPFKLEKLVDNYYRLVTERTLDRELI 415
Query: 69 IGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXX 128
G + + + + T S +S+ V D+NDN+P + Y+ + E
Sbjct: 416 SGYN---ITITAIDQGTPALSTETHISLLVTDINDNSPVFHQDSYSAYIPENNPRGASIF 472
Query: 129 XXXXSDRDQPG----PHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIK 184
D D +S + + P S YL ++ ++ + D+E + +K
Sbjct: 473 SVRAHDLDSNENAQITYSLIEDTIQGAPLSAYLSINSDTG-VLYALRSFDYEQFRDMQLK 531
Query: 185 LRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTF---LTTSPG-- 239
+ +D G PPL S+ +L + +LD +D P+ Y LP D G L+ PG
Sbjct: 532 VMARDSGDPPLSSNVSLSLFLLDQNDNAPEILY----PALPTDGSTGVELAPLSAEPGYL 587
Query: 240 --PISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKAT 296
+ A D+D G NA L Y L V TG+V + L+ ++V+
Sbjct: 588 VTKVVAVDRDSGQNAWLSYRLLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQ 647
Query: 297 QVDNPDRYALATL 309
P A TL
Sbjct: 648 DHGQPPLSATVTL 660
Score = 64.1 bits (149), Expect = 2e-09
Identities = 53/216 (24%), Positives = 92/216 (42%), Gaps = 12/216 (5%)
Query: 92 IPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPG 151
+ V ++V DVNDNAP+ V E D+D + +PG
Sbjct: 331 VKVLIKVLDVNDNAPEVTITSVTTAVPENFPPGTIIALISVHDQDSGD--NGYTTCFIPG 388
Query: 152 PHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQ 211
L + +V ++ LD E ++ + I + DQG+P L ++T + + V D +D
Sbjct: 389 NLPFKLEKLVDNYYRLVTERTLDRELISGYNITITAIDQGTPALSTETHISLLVTDINDN 448
Query: 212 NPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQ------L 265
+P F + Y+A +P++ G + + + A D D NA + YS D Q
Sbjct: 449 SPVFHQDSYSAYIPENNPRGASIFS----VRAHDLDSNENAQITYSLIEDTIQGAPLSAY 504
Query: 266 IVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNP 301
+ +N DTG + A + E + + + A +P
Sbjct: 505 LSINSDTGVLYALRSFDYEQFRDMQLKVMARDSGDP 540
>AY013878-1|AAK21988.1| 776|Homo sapiens protocadherin beta 8a
protein.
Length = 776
Score = 100 bits (240), Expect = 2e-20
Identities = 104/445 (23%), Positives = 182/445 (40%), Gaps = 27/445 (6%)
Query: 3 GGAVESFFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAA--VGIVPGSKNLTL 59
G + S+ + E+T GS + L + G ++ R+ +G + + + +L +
Sbjct: 27 GAELGSYSVVEETERGSFVANLGKDLGLGLTEMSTRKARIISQGNKQHLQLKAQTGDLLI 86
Query: 60 LRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSE 119
LDREE GP+ + + +P + +RV D+ND++P + +++ E
Sbjct: 87 NEKLDREELCGPTEPCI--LHFQVLMENPLEIFQAELRVIDINDHSPMFTEKEMILKIPE 144
Query: 120 TXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFE---NELEPIIVVKKPLDFE 176
D D G ++ +Y + P H L E P +V+ K LD E
Sbjct: 145 NSPLGTEFPLNHALDLDV-GSNNVQNYKISPSSHFRVLIHEFRDGRKYPELVLDKELDRE 203
Query: 177 TVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTT 236
+ L D GSPP +++ V+D +D P+F Y +P+++ G+ + T
Sbjct: 204 EEPQLRLTLTALDGGSPPRSGTAQVRIEVVDINDNAPEFEQPIYKVQIPENSPLGSLVAT 263
Query: 237 SPGPISAADQDLGINAPLQYS---STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVL 293
+SA D D G N + Y+ + D + + VN TG+V KQ+ E+ S + +
Sbjct: 264 ----VSARDLDGGANGKISYTLFQPSEDISKTLEVNPMTGEVRLRKQVDFEMVTSYEVRI 319
Query: 294 KATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTV 353
KAT D TL Q T ++ + E SP V+ +
Sbjct: 320 KAT--DGGGLSGKCTLLLQVVDVNDNPP-----QVTMSALTSPIPEN-SPEIVVAVFSVS 371
Query: 354 PQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSIS--- 410
++ + D FL K ++ N ++ R+LD E + Y + VTD +
Sbjct: 372 DPDSGNNGKTISSIQEDLPFLLKPSVKNFYTLVTERALDREARAEYNITLTVTDMGTPRL 431
Query: 411 NDTASINISVEDVNEWEPRFRHPQY 435
+I + + DVN+ P F Y
Sbjct: 432 KTEHNITVQISDVNDNAPTFTQTSY 456
Score = 84.2 bits (199), Expect = 2e-15
Identities = 116/480 (24%), Positives = 182/480 (37%), Gaps = 34/480 (7%)
Query: 57 LTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVR 116
L L + LDREE+ + + + + S V + V D+NDNAP++E Y V+
Sbjct: 194 LVLDKELDREEE---PQLRLTLTALDGGSPPRSGTAQVRIEVVDINDNAPEFEQPIYKVQ 250
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPI---IVVKKPL 173
+ E D D G + + Y + SE + E+ P+ + ++K +
Sbjct: 251 IPENSPLGSLVATVSARDLDG-GANGKISYTLFQP--SEDISKTLEVNPMTGEVRLRKQV 307
Query: 174 DFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTF 233
DFE V ++ ++++ D G L TL + V+D +D P+ T T+ +P+++ E
Sbjct: 308 DFEMVTSYEVRIKATDGGG--LSGKCTLLLQVVDVNDNPPQVTMSALTSPIPENSPEIVV 365
Query: 234 LTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVN-KDTGQVAATKQLIAELDPSVTIV 292
S +D D G N S D L+ + K+ + + L E I
Sbjct: 366 AV-----FSVSDPDSGNNGKTISSIQEDLPFLLKPSVKNFYTLVTERALDREARAEYNIT 420
Query: 293 LKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASP----GSVLL 348
L T + P L T FTQ Y+ V E SP GSV
Sbjct: 421 LTVTDMGTP---RLKT--EHNITVQISDVNDNAPTFTQTSYTLFVRENNSPALHIGSVSA 475
Query: 349 TLTTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTD 407
T N + S L +IN + G + RSLDYE + ++V TD
Sbjct: 476 TDRDSGTNAQVTYSLLPPQDPHLPLASLVSINADNGHLFALRSLDYEALREFEFRVSATD 535
Query: 408 SIS---NDTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGD 464
S + A + + V D N+ P +P VA DGD
Sbjct: 536 RGSPALSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVTKVVAVDGD 595
Query: 465 AGTLA-LS---LAGQHARMFYINASGDLFLREEAIGNLNSSSLHLVATAIDSGIPPRQTS 520
+G A LS L +F + A + +++ LV D+G PPR +
Sbjct: 596 SGQNAWLSYQLLKATEPGLFGVWAHNGEVRTARLLSERDAAKQRLVVLVKDNGEPPRSAT 655
Score = 82.2 bits (194), Expect = 7e-15
Identities = 89/314 (28%), Positives = 136/314 (43%), Gaps = 26/314 (8%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLL---RALDREE 67
I E++P ++ SV+ S + G +QE + + P KN L RALDRE
Sbjct: 356 IPENSP-EIVVAVFSVSDPDSGNNGKTISSIQEDLPFL-LKPSVKNFYTLVTERALDREA 413
Query: 68 KIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXX 127
+ + + + T ++V++ DVNDNAP + Y + V E
Sbjct: 414 R---AEYNITLTVTDMGTPRLKTEHNITVQISDVNDNAPTFTQTSYTLFVRENNSPALHI 470
Query: 128 XXXXXSDRDQPGPHSALHYAVLP--GPHSEYLGFE--NELEPIIVVKKPLDFETVNNFTI 183
+DRD G ++ + Y++LP PH N + + LD+E + F
Sbjct: 471 GSVSATDRDS-GTNAQVTYSLLPPQDPHLPLASLVSINADNGHLFALRSLDYEALREFEF 529
Query: 184 KLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTY------EHYTALLPDDAEEGTFLTTS 237
++ D+GSP L S+ ++V VLDA+D +P Y T L+P AE G +T
Sbjct: 530 RVSATDRGSPALSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVT-- 587
Query: 238 PGPISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPS-VTIVLKA 295
+ A D D G NA L Y L V G+V T +L++E D + +V+
Sbjct: 588 --KVVAVDGDSGQNAWLSYQLLKATEPGLFGVWAHNGEV-RTARLLSERDAAKQRLVVLV 644
Query: 296 TQVDNPDRYALATL 309
P R A ATL
Sbjct: 645 KDNGEPPRSATATL 658
>AF282973-2|AAG10030.1| 776|Homo sapiens protocadherin-3x protein.
Length = 776
Score = 100 bits (240), Expect = 2e-20
Identities = 104/445 (23%), Positives = 182/445 (40%), Gaps = 27/445 (6%)
Query: 3 GGAVESFFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAA--VGIVPGSKNLTL 59
G + S+ + E+T GS + L + G ++ R+ +G + + + +L +
Sbjct: 27 GAELGSYSVVEETERGSFVANLGKDLGLGLTEMSTRKARIISQGNKQHLQLKAQTGDLLI 86
Query: 60 LRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSE 119
LDREE GP+ + + +P + +RV D+ND++P + +++ E
Sbjct: 87 NEKLDREELCGPTEPCI--LHFQVLMENPLEIFQAELRVIDINDHSPMFTEKEMILKIPE 144
Query: 120 TXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFE---NELEPIIVVKKPLDFE 176
D D G ++ +Y + P H L E P +V+ K LD E
Sbjct: 145 NSPLGTEFPLNHALDLDV-GSNNVQNYKISPSSHFRVLIHEFRDGRKYPELVLDKELDRE 203
Query: 177 TVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTT 236
+ L D GSPP +++ V+D +D P+F Y +P+++ G+ + T
Sbjct: 204 EEPQLRLTLTALDGGSPPRSGTAQVRIEVVDINDNAPEFEQPIYKVQIPENSPLGSLVAT 263
Query: 237 SPGPISAADQDLGINAPLQYS---STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVL 293
+SA D D G N + Y+ + D + + VN TG+V KQ+ E+ S + +
Sbjct: 264 ----VSARDLDGGANGKISYTLFQPSEDISKTLEVNPMTGEVRLRKQVDFEMVTSYEVRI 319
Query: 294 KATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTV 353
KAT D TL Q T ++ + E SP V+ +
Sbjct: 320 KAT--DGGGLSGKCTLLLQVVDVNDNPP-----QVTMSALTSPIPEN-SPEIVVAVFSVS 371
Query: 354 PQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSIS--- 410
++ + D FL K ++ N ++ R+LD E + Y + VTD +
Sbjct: 372 DPDSGNNGKTISSIQEDLPFLLKPSVKNFYTLVTERALDREARAEYNITLTVTDMGTPRL 431
Query: 411 NDTASINISVEDVNEWEPRFRHPQY 435
+I + + DVN+ P F Y
Sbjct: 432 KTEHNITVQISDVNDNAPTFTQTSY 456
Score = 82.2 bits (194), Expect = 7e-15
Identities = 116/480 (24%), Positives = 182/480 (37%), Gaps = 34/480 (7%)
Query: 57 LTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVR 116
L L + LDREE+ + + + + S V + V D+NDNAP++E Y V+
Sbjct: 194 LVLDKELDREEE---PQLRLTLTALDGGSPPRSGTAQVRIEVVDINDNAPEFEQPIYKVQ 250
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPI---IVVKKPL 173
+ E D D G + + Y + SE + E+ P+ + ++K +
Sbjct: 251 IPENSPLGSLVATVSARDLDG-GANGKISYTLFQP--SEDISKTLEVNPMTGEVRLRKQV 307
Query: 174 DFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTF 233
DFE V ++ ++++ D G L TL + V+D +D P+ T T+ +P+++ E
Sbjct: 308 DFEMVTSYEVRIKATDGGG--LSGKCTLLLQVVDVNDNPPQVTMSALTSPIPENSPEIVV 365
Query: 234 LTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVN-KDTGQVAATKQLIAELDPSVTIV 292
S +D D G N S D L+ + K+ + + L E I
Sbjct: 366 AV-----FSVSDPDSGNNGKTISSIQEDLPFLLKPSVKNFYTLVTERALDREARAEYNIT 420
Query: 293 LKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASP----GSVLL 348
L T + P L T FTQ Y+ V E SP GSV
Sbjct: 421 LTVTDMGTP---RLKT--EHNITVQISDVNDNAPTFTQTSYTLFVRENNSPALHIGSVSA 475
Query: 349 TLTTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTD 407
T N + S L +IN + G + RSLDYE + ++V TD
Sbjct: 476 TDRDSGTNAQVTYSLLPPQDPHLPLASLVSINADNGHLFALRSLDYEALQAFEFRVGATD 535
Query: 408 SIS---NDTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGD 464
S + A + + V D N+ P +P VA DGD
Sbjct: 536 RGSPALSREALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVTKVVAVDGD 595
Query: 465 AGTLA-LS---LAGQHARMFYINASGDLFLREEAIGNLNSSSLHLVATAIDSGIPPRQTS 520
+G A LS L +F + A + +++ LV D+G PPR +
Sbjct: 596 SGQNAWLSYQLLKATEPGLFGVWAHNGEVRTARLLSERDAAKQRLVVLVKDNGEPPRSAT 655
Score = 79.0 bits (186), Expect = 7e-14
Identities = 88/314 (28%), Positives = 135/314 (42%), Gaps = 26/314 (8%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLL---RALDREE 67
I E++P ++ SV+ S + G +QE + + P KN L RALDRE
Sbjct: 356 IPENSP-EIVVAVFSVSDPDSGNNGKTISSIQEDLPFL-LKPSVKNFYTLVTERALDREA 413
Query: 68 KIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXX 127
+ + + + T ++V++ DVNDNAP + Y + V E
Sbjct: 414 R---AEYNITLTVTDMGTPRLKTEHNITVQISDVNDNAPTFTQTSYTLFVRENNSPALHI 470
Query: 128 XXXXXSDRDQPGPHSALHYAVLP--GPHSEYLGFE--NELEPIIVVKKPLDFETVNNFTI 183
+DRD G ++ + Y++LP PH N + + LD+E + F
Sbjct: 471 GSVSATDRDS-GTNAQVTYSLLPPQDPHLPLASLVSINADNGHLFALRSLDYEALQAFEF 529
Query: 184 KLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTY------EHYTALLPDDAEEGTFLTTS 237
++ D+GSP L + ++V VLDA+D +P Y T L+P AE G +T
Sbjct: 530 RVGATDRGSPALSREALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVT-- 587
Query: 238 PGPISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPS-VTIVLKA 295
+ A D D G NA L Y L V G+V T +L++E D + +V+
Sbjct: 588 --KVVAVDGDSGQNAWLSYQLLKATEPGLFGVWAHNGEV-RTARLLSERDAAKQRLVVLV 644
Query: 296 TQVDNPDRYALATL 309
P R A ATL
Sbjct: 645 KDNGEPPRSATATL 658
>AF217757-1|AAF81914.1| 776|Homo sapiens protocadherin 3X protein.
Length = 776
Score = 100 bits (240), Expect = 2e-20
Identities = 104/445 (23%), Positives = 182/445 (40%), Gaps = 27/445 (6%)
Query: 3 GGAVESFFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAA--VGIVPGSKNLTL 59
G + S+ + E+T GS + L + G ++ R+ +G + + + +L +
Sbjct: 27 GAELGSYSVVEETERGSFVANLGKDLGLGLTEMSTRKARIISQGNKQHLQLKAQTGDLLI 86
Query: 60 LRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSE 119
LDREE GP+ + + +P + +RV D+ND++P + +++ E
Sbjct: 87 NEKLDREELCGPTEPCI--LHFQVLMENPLEIFQAELRVIDINDHSPMFTEKEMILKIPE 144
Query: 120 TXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFE---NELEPIIVVKKPLDFE 176
D D G ++ +Y + P H L E P +V+ K LD E
Sbjct: 145 NSPLGTEFPLNHALDLDV-GSNNVQNYKISPSSHFRVLIHEFRDGRKYPELVLDKELDRE 203
Query: 177 TVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTT 236
+ L D GSPP +++ V+D +D P+F Y +P+++ G+ + T
Sbjct: 204 EEPQLRLTLTALDGGSPPRSGTAQVRIEVVDINDNAPEFEQPIYKVQIPENSPLGSLVAT 263
Query: 237 SPGPISAADQDLGINAPLQYS---STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVL 293
+SA D D G N + Y+ + D + + VN TG+V KQ+ E+ S + +
Sbjct: 264 ----VSARDLDGGANGKISYTLFQPSEDISKTLEVNPMTGEVRLRKQVDFEMVTSYEVRI 319
Query: 294 KATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTV 353
KAT D TL Q T ++ + E SP V+ +
Sbjct: 320 KAT--DGGGLSGKCTLLLQVVDVNDNPP-----QVTMSALTSPIPEN-SPEIVVAVFSVS 371
Query: 354 PQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSIS--- 410
++ + D FL K ++ N ++ R+LD E + Y + VTD +
Sbjct: 372 DPDSGNNGKTISSIQEDLPFLLKPSVKNFYTLVTERALDREARAEYNITLTVTDMGTPRL 431
Query: 411 NDTASINISVEDVNEWEPRFRHPQY 435
+I + + DVN+ P F Y
Sbjct: 432 KTEHNITVQISDVNDNAPTFTQTSY 456
Score = 82.2 bits (194), Expect = 7e-15
Identities = 116/480 (24%), Positives = 182/480 (37%), Gaps = 34/480 (7%)
Query: 57 LTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVR 116
L L + LDREE+ + + + + S V + V D+NDNAP++E Y V+
Sbjct: 194 LVLDKELDREEE---PQLRLTLTALDGGSPPRSGTAQVRIEVVDINDNAPEFEQPIYKVQ 250
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPI---IVVKKPL 173
+ E D D G + + Y + SE + E+ P+ + ++K +
Sbjct: 251 IPENSPLGSLVATVSARDLDG-GANGKISYTLFQP--SEDISKTLEVNPMTGEVRLRKQV 307
Query: 174 DFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTF 233
DFE V ++ ++++ D G L TL + V+D +D P+ T T+ +P+++ E
Sbjct: 308 DFEMVTSYEVRIKATDGGG--LSGKCTLLLQVVDVNDNPPQVTMSALTSPIPENSPEIVV 365
Query: 234 LTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVN-KDTGQVAATKQLIAELDPSVTIV 292
S +D D G N S D L+ + K+ + + L E I
Sbjct: 366 AV-----FSVSDPDSGNNGKTISSIQEDLPFLLKPSVKNFYTLVTERALDREARAEYNIT 420
Query: 293 LKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASP----GSVLL 348
L T + P L T FTQ Y+ V E SP GSV
Sbjct: 421 LTVTDMGTP---RLKT--EHNITVQISDVNDNAPTFTQTSYTLFVRENNSPALHIGSVSA 475
Query: 349 TLTTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTD 407
T N + S L +IN + G + RSLDYE + ++V TD
Sbjct: 476 TDRDSGTNAQVTYSLLPPQDPHLPLASLVSINADNGHLFALRSLDYEALQAFEFRVGATD 535
Query: 408 SIS---NDTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGD 464
S + A + + V D N+ P +P VA DGD
Sbjct: 536 RGSPALSREALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVTKVVAVDGD 595
Query: 465 AGTLA-LS---LAGQHARMFYINASGDLFLREEAIGNLNSSSLHLVATAIDSGIPPRQTS 520
+G A LS L +F + A + +++ LV D+G PPR +
Sbjct: 596 SGQNAWLSYQLLKATEPGLFGVWAHNGEVRTARLLSERDAAKQRLVVLVKDNGEPPRSAT 655
Score = 79.0 bits (186), Expect = 7e-14
Identities = 88/314 (28%), Positives = 135/314 (42%), Gaps = 26/314 (8%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLL---RALDREE 67
I E++P ++ SV+ S + G +QE + + P KN L RALDRE
Sbjct: 356 IPENSP-EIVVAVFSVSDPDSGNNGKTISSIQEDLPFL-LKPSVKNFYTLVTERALDREA 413
Query: 68 KIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXX 127
+ + + + T ++V++ DVNDNAP + Y + V E
Sbjct: 414 R---AEYNITLTVTDMGTPRLKTEHNITVQISDVNDNAPTFTQTSYTLFVRENNSPALHI 470
Query: 128 XXXXXSDRDQPGPHSALHYAVLP--GPHSEYLGFE--NELEPIIVVKKPLDFETVNNFTI 183
+DRD G ++ + Y++LP PH N + + LD+E + F
Sbjct: 471 GSVSATDRDS-GTNAQVTYSLLPPQDPHLPLASLVSINADNGHLFALRSLDYEALQAFEF 529
Query: 184 KLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTY------EHYTALLPDDAEEGTFLTTS 237
++ D+GSP L + ++V VLDA+D +P Y T L+P AE G +T
Sbjct: 530 RVGATDRGSPALSREALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVT-- 587
Query: 238 PGPISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPS-VTIVLKA 295
+ A D D G NA L Y L V G+V T +L++E D + +V+
Sbjct: 588 --KVVAVDGDSGQNAWLSYQLLKATEPGLFGVWAHNGEV-RTARLLSERDAAKQRLVVLV 644
Query: 296 TQVDNPDRYALATL 309
P R A ATL
Sbjct: 645 KDNGEPPRSATATL 658
>AF152507-1|AAD43768.1| 823|Homo sapiens protocadherin gamma A1
short form protein protein.
Length = 823
Score = 100 bits (240), Expect = 2e-20
Identities = 105/443 (23%), Positives = 183/443 (41%), Gaps = 34/443 (7%)
Query: 9 FFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAA--VGIVPGSKNLTLLRALDR 65
+ + E+T GS +G ++ + G ++L D +R+ +G + P S +L R +DR
Sbjct: 33 YSVPEETDKGSFVGNIAKDLGLQPQELADGGVRIVSRGRMPLFALNPRSGSLITARRIDR 92
Query: 66 EEKIG---PSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXX 122
EE P V N+ + D + PV V + D+NDN PQ++ +++E
Sbjct: 93 EELCAQSMPCLVSFNILVE-----DKMKLFPVEVEIIDINDNTPQFQLEELEFKMNEITT 147
Query: 123 XXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEY---LGFENELEPIIVVKKPLDFETVN 179
D D G +S Y + PH G + P +V++ PLD E
Sbjct: 148 PGTRVSLPFGQDLDV-GMNSLQSYQLSSNPHFSLDVQQGADGPQHPEMVLQSPLDREEEA 206
Query: 180 NFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPG 239
+ L D G P + + V+DA+D P FT Y +P++ GT L
Sbjct: 207 VHHLILTASDGGEPVRSGTLRIYIQVVDANDNPPAFTQAQYHINVPENVPLGTQLLM--- 263
Query: 240 PISAADQDLGINAPLQYS-STGDHK--QLIVVNKDTGQVAATKQLIAELDPSVTIVLKAT 296
++A D D G N + YS DH+ Q+ ++ TG+++ + L E + +
Sbjct: 264 -VNATDPDEGANGEVTYSFHNVDHRVAQIFRLDSYTGEISNKEPLDFE-----EYKMYSM 317
Query: 297 QVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQN 356
+V D L + + T +T V E PG+++ ++ Q+
Sbjct: 318 EVQAQDGAGL--MAKVKVLIKVLDVNDNAPEVTITSVTTAVPENFPPGTIIALISVHDQD 375
Query: 357 TEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTD----SISND 412
+ F + F + ++N ++ R+LD E S Y + D ++S +
Sbjct: 376 SGDNGYTTCFIPGNLPFKLEKLVDNYYRLVTERTLDRELISGYNITITAIDQGTPALSTE 435
Query: 413 TASINISVEDVNEWEPRFRHPQY 435
T I++ V D+N+ P F Y
Sbjct: 436 T-HISLLVTDINDNSPVFHQDSY 457
Score = 75.8 bits (178), Expect = 6e-13
Identities = 78/313 (24%), Positives = 124/313 (39%), Gaps = 22/313 (7%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEK--GAAVGIVPGSKNLTLLRALDREEK 68
+ E+ P G+II +SV+ S D G T + +V L R LDRE
Sbjct: 356 VPENFPPGTIIALISVHDQDSGDNGYTTCFIPGNLPFKLEKLVDNYYRLVTERTLDRELI 415
Query: 69 IGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXX 128
G + + + + T S +S+ V D+NDN+P + Y+ + E
Sbjct: 416 SGYN---ITITAIDQGTPALSTETHISLLVTDINDNSPVFHQDSYSAYIPENNPRGASIF 472
Query: 129 XXXXSDRDQPG----PHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIK 184
D D +S + + P S YL ++ ++ + D+E + +K
Sbjct: 473 SVRAHDLDSNENAQITYSLIEDTIQGAPLSAYLSINSDTG-VLYALRSFDYEQFRDMQLK 531
Query: 185 LRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTF---LTTSPG-- 239
+ +D G PPL S+ +L + +LD +D P+ Y LP D G L+ PG
Sbjct: 532 VMARDSGDPPLSSNVSLSLFLLDQNDNAPEILY----PALPTDGSTGVELAPLSAEPGYL 587
Query: 240 --PISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKAT 296
+ A D+D G NA L Y L V TG+V + L+ ++V+
Sbjct: 588 VTKVVAVDRDSGQNAWLSYRLLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQ 647
Query: 297 QVDNPDRYALATL 309
P A TL
Sbjct: 648 DHGQPPLSATVTL 660
Score = 64.1 bits (149), Expect = 2e-09
Identities = 53/216 (24%), Positives = 92/216 (42%), Gaps = 12/216 (5%)
Query: 92 IPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPG 151
+ V ++V DVNDNAP+ V E D+D + +PG
Sbjct: 331 VKVLIKVLDVNDNAPEVTITSVTTAVPENFPPGTIIALISVHDQDSGD--NGYTTCFIPG 388
Query: 152 PHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQ 211
L + +V ++ LD E ++ + I + DQG+P L ++T + + V D +D
Sbjct: 389 NLPFKLEKLVDNYYRLVTERTLDRELISGYNITITAIDQGTPALSTETHISLLVTDINDN 448
Query: 212 NPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQ------L 265
+P F + Y+A +P++ G + + + A D D NA + YS D Q
Sbjct: 449 SPVFHQDSYSAYIPENNPRGASIFS----VRAHDLDSNENAQITYSLIEDTIQGAPLSAY 504
Query: 266 IVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNP 301
+ +N DTG + A + E + + + A +P
Sbjct: 505 LSINSDTGVLYALRSFDYEQFRDMQLKVMARDSGDP 540
>AF152318-1|AAD43712.1| 931|Homo sapiens protocadherin gamma A1
protein.
Length = 931
Score = 100 bits (240), Expect = 2e-20
Identities = 105/443 (23%), Positives = 183/443 (41%), Gaps = 34/443 (7%)
Query: 9 FFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAA--VGIVPGSKNLTLLRALDR 65
+ + E+T GS +G ++ + G ++L D +R+ +G + P S +L R +DR
Sbjct: 33 YSVPEETDKGSFVGNIAKDLGLQPQELADGGVRIVSRGRMPLFALNPRSGSLITARRIDR 92
Query: 66 EEKIG---PSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXX 122
EE P V N+ + D + PV V + D+NDN PQ++ +++E
Sbjct: 93 EELCAQSMPCLVSFNILVE-----DKMKLFPVEVEIIDINDNTPQFQLEELEFKMNEITT 147
Query: 123 XXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEY---LGFENELEPIIVVKKPLDFETVN 179
D D G +S Y + PH G + P +V++ PLD E
Sbjct: 148 PGTRVSLPFGQDLDV-GMNSLQSYQLSSNPHFSLDVQQGADGPQHPEMVLQSPLDREEEA 206
Query: 180 NFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPG 239
+ L D G P + + V+DA+D P FT Y +P++ GT L
Sbjct: 207 VHHLILTASDGGEPVRSGTLRIYIQVVDANDNPPAFTQAQYHINVPENVPLGTQLLM--- 263
Query: 240 PISAADQDLGINAPLQYS-STGDHK--QLIVVNKDTGQVAATKQLIAELDPSVTIVLKAT 296
++A D D G N + YS DH+ Q+ ++ TG+++ + L E + +
Sbjct: 264 -VNATDPDEGANGEVTYSFHNVDHRVAQIFRLDSYTGEISNKEPLDFE-----EYKMYSM 317
Query: 297 QVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQN 356
+V D L + + T +T V E PG+++ ++ Q+
Sbjct: 318 EVQAQDGAGL--MAKVKVLIKVLDVNDNAPEVTITSVTTAVPENFPPGTIIALISVHDQD 375
Query: 357 TEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTD----SISND 412
+ F + F + ++N ++ R+LD E S Y + D ++S +
Sbjct: 376 SGDNGYTTCFIPGNLPFKLEKLVDNYYRLVTERTLDRELISGYNITITAIDQGTPALSTE 435
Query: 413 TASINISVEDVNEWEPRFRHPQY 435
T I++ V D+N+ P F Y
Sbjct: 436 T-HISLLVTDINDNSPVFHQDSY 457
Score = 75.8 bits (178), Expect = 6e-13
Identities = 78/313 (24%), Positives = 124/313 (39%), Gaps = 22/313 (7%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEK--GAAVGIVPGSKNLTLLRALDREEK 68
+ E+ P G+II +SV+ S D G T + +V L R LDRE
Sbjct: 356 VPENFPPGTIIALISVHDQDSGDNGYTTCFIPGNLPFKLEKLVDNYYRLVTERTLDRELI 415
Query: 69 IGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXX 128
G + + + + T S +S+ V D+NDN+P + Y+ + E
Sbjct: 416 SGYN---ITITAIDQGTPALSTETHISLLVTDINDNSPVFHQDSYSAYIPENNPRGASIF 472
Query: 129 XXXXSDRDQPG----PHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIK 184
D D +S + + P S YL ++ ++ + D+E + +K
Sbjct: 473 SVRAHDLDSNENAQITYSLIEDTIQGAPLSAYLSINSDTG-VLYALRSFDYEQFRDMQLK 531
Query: 185 LRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTF---LTTSPG-- 239
+ +D G PPL S+ +L + +LD +D P+ Y LP D G L+ PG
Sbjct: 532 VMARDSGDPPLSSNVSLSLFLLDQNDNAPEILY----PALPTDGSTGVELAPLSAEPGYL 587
Query: 240 --PISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKAT 296
+ A D+D G NA L Y L V TG+V + L+ ++V+
Sbjct: 588 VTKVVAVDRDSGQNAWLSYRLLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQ 647
Query: 297 QVDNPDRYALATL 309
P A TL
Sbjct: 648 DHGQPPLSATVTL 660
Score = 64.1 bits (149), Expect = 2e-09
Identities = 53/216 (24%), Positives = 92/216 (42%), Gaps = 12/216 (5%)
Query: 92 IPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPG 151
+ V ++V DVNDNAP+ V E D+D + +PG
Sbjct: 331 VKVLIKVLDVNDNAPEVTITSVTTAVPENFPPGTIIALISVHDQDSGD--NGYTTCFIPG 388
Query: 152 PHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQ 211
L + +V ++ LD E ++ + I + DQG+P L ++T + + V D +D
Sbjct: 389 NLPFKLEKLVDNYYRLVTERTLDRELISGYNITITAIDQGTPALSTETHISLLVTDINDN 448
Query: 212 NPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQ------L 265
+P F + Y+A +P++ G + + + A D D NA + YS D Q
Sbjct: 449 SPVFHQDSYSAYIPENNPRGASIFS----VRAHDLDSNENAQITYSLIEDTIQGAPLSAY 504
Query: 266 IVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNP 301
+ +N DTG + A + E + + + A +P
Sbjct: 505 LSINSDTGVLYALRSFDYEQFRDMQLKVMARDSGDP 540
>AB046841-1|BAB13447.1| 787|Homo sapiens KIAA1621 protein protein.
Length = 787
Score = 100 bits (240), Expect = 2e-20
Identities = 104/445 (23%), Positives = 182/445 (40%), Gaps = 27/445 (6%)
Query: 3 GGAVESFFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAA--VGIVPGSKNLTL 59
G + S+ + E+T GS + L + G ++ R+ +G + + + +L +
Sbjct: 38 GAELGSYSVVEETERGSFVANLGKDLGLGLTEMSTRKARIISQGNKQHLQLKAQTGDLLI 97
Query: 60 LRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSE 119
LDREE GP+ + + +P + +RV D+ND++P + +++ E
Sbjct: 98 NEKLDREELCGPTEPCI--LHFQVLMENPLEIFQAELRVIDINDHSPMFTEKEMILKIPE 155
Query: 120 TXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFE---NELEPIIVVKKPLDFE 176
D D G ++ +Y + P H L E P +V+ K LD E
Sbjct: 156 NSPLGTEFPLNHALDLDV-GSNNVQNYKISPSSHFRVLIHEFRDGRKYPELVLDKELDRE 214
Query: 177 TVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTT 236
+ L D GSPP +++ V+D +D P+F Y +P+++ G+ + T
Sbjct: 215 EEPQLRLTLTALDGGSPPRSGTAQVRIEVVDINDNAPEFEQPIYKVQIPENSPLGSLVAT 274
Query: 237 SPGPISAADQDLGINAPLQYS---STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVL 293
+SA D D G N + Y+ + D + + VN TG+V KQ+ E+ S + +
Sbjct: 275 ----VSARDLDGGANGKISYTLFQPSEDISKTLEVNPMTGEVRLRKQVDFEMVTSYEVRI 330
Query: 294 KATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTV 353
KAT D TL Q T ++ + E SP V+ +
Sbjct: 331 KAT--DGGGLSGKCTLLLQVVDVNDNPP-----QVTMSALTSPIPEN-SPEIVVAVFSVS 382
Query: 354 PQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSIS--- 410
++ + D FL K ++ N ++ R+LD E + Y + VTD +
Sbjct: 383 DPDSGNNGKTISSIQEDLPFLLKPSVKNFYTLVTERALDREARAEYNITLTVTDMGTPRL 442
Query: 411 NDTASINISVEDVNEWEPRFRHPQY 435
+I + + DVN+ P F Y
Sbjct: 443 KTEHNITVQISDVNDNAPTFTQTSY 467
Score = 80.6 bits (190), Expect = 2e-14
Identities = 115/476 (24%), Positives = 180/476 (37%), Gaps = 34/476 (7%)
Query: 57 LTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVR 116
L L + LDREE+ + + + + S V + V D+NDNAP++E Y V+
Sbjct: 205 LVLDKELDREEE---PQLRLTLTALDGGSPPRSGTAQVRIEVVDINDNAPEFEQPIYKVQ 261
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPI---IVVKKPL 173
+ E D D G + + Y + SE + E+ P+ + ++K +
Sbjct: 262 IPENSPLGSLVATVSARDLDG-GANGKISYTLFQP--SEDISKTLEVNPMTGEVRLRKQV 318
Query: 174 DFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTF 233
DFE V ++ ++++ D G L TL + V+D +D P+ T T+ +P+++ E
Sbjct: 319 DFEMVTSYEVRIKATDGGG--LSGKCTLLLQVVDVNDNPPQVTMSALTSPIPENSPEIVV 376
Query: 234 LTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVN-KDTGQVAATKQLIAELDPSVTIV 292
S +D D G N S D L+ + K+ + + L E I
Sbjct: 377 AV-----FSVSDPDSGNNGKTISSIQEDLPFLLKPSVKNFYTLVTERALDREARAEYNIT 431
Query: 293 LKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASP----GSVLL 348
L T + P L T FTQ Y+ V E SP GSV
Sbjct: 432 LTVTDMGTP---RLKT--EHNITVQISDVNDNAPTFTQTSYTLFVRENNSPALHIGSVSA 486
Query: 349 TLTTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTD 407
T N + S L +IN + G + RSLDYE + ++V TD
Sbjct: 487 TDRDSGINAQVTYSLLPPQDPHLPLASLVSINADNGHLFALRSLDYEALREFEFRVSATD 546
Query: 408 SIS---NDTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGD 464
S + A + + V D N+ P +P VA DGD
Sbjct: 547 RGSPALSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVTKVVAVDGD 606
Query: 465 AGTLA-LS---LAGQHARMFYINASGDLFLREEAIGNLNSSSLHLVATAIDSGIPP 516
+G A LS L +F + A + +++ LV D+G PP
Sbjct: 607 SGQNAWLSYQLLKATEPGLFGVWAHNGEVRTARLLSERDAAKHRLVVLVKDNGEPP 662
Score = 78.2 bits (184), Expect = 1e-13
Identities = 88/314 (28%), Positives = 135/314 (42%), Gaps = 26/314 (8%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLL---RALDREE 67
I E++P ++ SV+ S + G +QE + + P KN L RALDRE
Sbjct: 367 IPENSP-EIVVAVFSVSDPDSGNNGKTISSIQEDLPFL-LKPSVKNFYTLVTERALDREA 424
Query: 68 KIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXX 127
+ + + + T ++V++ DVNDNAP + Y + V E
Sbjct: 425 R---AEYNITLTVTDMGTPRLKTEHNITVQISDVNDNAPTFTQTSYTLFVRENNSPALHI 481
Query: 128 XXXXXSDRDQPGPHSALHYAVLP--GPHSEYLGFE--NELEPIIVVKKPLDFETVNNFTI 183
+DRD G ++ + Y++LP PH N + + LD+E + F
Sbjct: 482 GSVSATDRDS-GINAQVTYSLLPPQDPHLPLASLVSINADNGHLFALRSLDYEALREFEF 540
Query: 184 KLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTY------EHYTALLPDDAEEGTFLTTS 237
++ D+GSP L S+ ++V VLDA+D +P Y T L+P AE G +T
Sbjct: 541 RVSATDRGSPALSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVT-- 598
Query: 238 PGPISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPSV-TIVLKA 295
+ A D D G NA L Y L V G+V T +L++E D + +V+
Sbjct: 599 --KVVAVDGDSGQNAWLSYQLLKATEPGLFGVWAHNGEV-RTARLLSERDAAKHRLVVLV 655
Query: 296 TQVDNPDRYALATL 309
P A ATL
Sbjct: 656 KDNGEPPCSATATL 669
>BC113607-1|AAI13608.1| 803|Homo sapiens protocadherin gamma
subfamily B, 4 protein.
Length = 803
Score = 99 bits (238), Expect = 3e-20
Identities = 103/433 (23%), Positives = 174/433 (40%), Gaps = 22/433 (5%)
Query: 11 ISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEKI 69
I E+ P GS++G L+ + G ++L LR+ + + S L + LDREE
Sbjct: 37 IPEEMPKGSVVGNLATDLGFSVQELPTRKLRVSSEKPYFTVSAESGELLVSSRLDREEIC 96
Query: 70 GPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXX 129
G +P V+V + D+ND+ P++ + +++SE+
Sbjct: 97 GKKPACALEF--EAVAENPLNFYHVNVEIEDINDHTPKFTQNSFELQISESAQPGTRFIL 154
Query: 130 XXXSDRDQPGPHSALHYAVLPGPHSEYLGFENE---LEPIIVVKKPLDFETVNNFTIKLR 186
D D G ++ +Y + P H + E P +V+K PLD E ++ + L
Sbjct: 155 GSAHDADI-GSNTLQNYQLSPSDHFSLINKEKSDGSKYPEMVLKTPLDREKQKSYHLTLT 213
Query: 187 VQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQ 246
D G+PPL S + V V DA+D P F+ + Y L ++ GT + ++A DQ
Sbjct: 214 ALDFGAPPLSSTAQIHVLVTDANDNAPVFSQDVYRVSLSENVYPGTTVL----QVTATDQ 269
Query: 247 DLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYA 305
D G+NA + +S S +N +TG++ L E +IVL+A D A
Sbjct: 270 DEGVNAEITFSFSEASQITQFDLNSNTGEITVLNTLDFEEVKEYSIVLEAR--DGGGMIA 327
Query: 306 LATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQ 365
T+ + + + E A G+ + L +++
Sbjct: 328 QCTVEVEVIDENDNAP-----EVIFQSLPNLIMEDAELGTHIALLKVRDKDSRHNGEVTC 382
Query: 366 FYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSIS---NDTASINISVED 422
D F + N +++ LD E Y V TD + ++SI + + D
Sbjct: 383 KLEGDVPFKILTSSRNTYKLVTDAVLDREQNPEYNITVTATDRGKPPLSSSSSITLHIGD 442
Query: 423 VNEWEPRFRHPQY 435
VN+ P F Y
Sbjct: 443 VNDNAPVFSQSSY 455
Score = 82.6 bits (195), Expect = 6e-15
Identities = 80/287 (27%), Positives = 122/287 (42%), Gaps = 26/287 (9%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLL---RALDREE 67
I ED +G+ I L V S G++T +L E I+ S+N L LDRE+
Sbjct: 354 IMEDAELGTHIALLKVRDKDSRHNGEVTCKL-EGDVPFKILTSSRNTYKLVTDAVLDREQ 412
Query: 68 KIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXX 127
+ V R S +++ + DVNDNAP + + Y V V+E
Sbjct: 413 N---PEYNITVTATDRGKPPLSSSSSITLHIGDVNDNAPVFSQSSYIVHVAENNPPGASI 469
Query: 128 XXXXXSDRDQPGPHSALHYAVLPGPH-----SEYLGFENELEPIIVVKKPLDFETVNNFT 182
SD D GP+ + Y ++ S Y+ E ++ ++ D E + F
Sbjct: 470 SQVRASDPDL-GPNGQVSYCIMASDLEQRELSSYVSISAE-SGVVFAQRAFDHEQLRAFE 527
Query: 183 IKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHY----TAL---LPDDAEEGTFLT 235
+ L+ +DQGSP L ++ +L+V V D +D P+ Y +AL +P AE G +T
Sbjct: 528 LTLQARDQGSPALSANVSLRVLVDDRNDNAPRVLYPALGPDGSALFDMVPHAAEPGYLVT 587
Query: 236 TSPGPISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQL 281
+ A D D G NA L Y L + TG+V + L
Sbjct: 588 ----KVVAVDADSGHNAWLSYHVLQASEPGLFSLGLRTGEVRTARAL 630
Score = 75.4 bits (177), Expect = 9e-13
Identities = 80/350 (22%), Positives = 146/350 (41%), Gaps = 24/350 (6%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
+ V V D NDNAP + Y V +SE +D+D+ G ++ + ++
Sbjct: 228 IHVLVTDANDNAPVFSQDVYRVSLSENVYPGTTVLQVTATDQDE-GVNAEITFSFSEA-- 284
Query: 154 SEYLGFE-NELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQN 212
S+ F+ N I V LDFE V ++I L +D G + + T++V V+D +D
Sbjct: 285 SQITQFDLNSNTGEITVLNTLDFEEVKEYSIVLEARDGGG--MIAQCTVEVEVIDENDNA 342
Query: 213 PKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHK-QLIVVNKD 271
P+ ++ L+ +DAE GT + + D+D N + GD +++ +++
Sbjct: 343 PEVIFQSLPNLIMEDAELGTHIAL----LKVRDKDSRHNGEVTCKLEGDVPFKILTSSRN 398
Query: 272 TGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQK 331
T ++ L E +P I + AT P + +++ F+Q
Sbjct: 399 TYKLVTDAVLDREQNPEYNITVTATDRGKPPLSSSSSITLHIGDVNDNAPV-----FSQS 453
Query: 332 QYSTTVSEGASPG-SVLLTLTTVPQ---NTEFRESPLQFYVSDRSFLDKFAIN-NAGEVI 386
Y V+E PG S+ + P N + + + R +I+ +G V
Sbjct: 454 SYIVHVAENNPPGASISQVRASDPDLGPNGQVSYCIMASDLEQRELSSYVSISAESGVVF 513
Query: 387 LRRSLDYETTSNYFYQVMVTDSIS---NDTASINISVEDVNEWEPRFRHP 433
+R+ D+E + + D S + S+ + V+D N+ PR +P
Sbjct: 514 AQRAFDHEQLRAFELTLQARDQGSPALSANVSLRVLVDDRNDNAPRVLYP 563
>BC112088-1|AAI12089.1| 803|Homo sapiens protocadherin gamma
subfamily B, 4, isoform 2 precursor protein.
Length = 803
Score = 99 bits (238), Expect = 3e-20
Identities = 103/433 (23%), Positives = 174/433 (40%), Gaps = 22/433 (5%)
Query: 11 ISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEKI 69
I E+ P GS++G L+ + G ++L LR+ + + S L + LDREE
Sbjct: 37 IPEEMPKGSVVGNLATDLGFSVQELPTRKLRVSSEKPYFTVSAESGELLVSSRLDREEIC 96
Query: 70 GPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXX 129
G +P V+V + D+ND+ P++ + +++SE+
Sbjct: 97 GKKPACALEF--EAVAENPLNFYHVNVEIEDINDHTPKFTQNSFELQISESAQPGTRFIL 154
Query: 130 XXXSDRDQPGPHSALHYAVLPGPHSEYLGFENE---LEPIIVVKKPLDFETVNNFTIKLR 186
D D G ++ +Y + P H + E P +V+K PLD E ++ + L
Sbjct: 155 GSAHDADI-GSNTLQNYQLSPSDHFSLINKEKSDGSKYPEMVLKTPLDREKQKSYHLTLT 213
Query: 187 VQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQ 246
D G+PPL S + V V DA+D P F+ + Y L ++ GT + ++A DQ
Sbjct: 214 ALDFGAPPLSSTAQIHVLVTDANDNAPVFSQDVYRVSLSENVYPGTTVL----QVTATDQ 269
Query: 247 DLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYA 305
D G+NA + +S S +N +TG++ L E +IVL+A D A
Sbjct: 270 DEGVNAEITFSFSEASQITQFDLNSNTGEITVLNTLDFEEVKEYSIVLEAR--DGGGMIA 327
Query: 306 LATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQ 365
T+ + + + E A G+ + L +++
Sbjct: 328 QCTVEVEVIDENDNAP-----EVIFQSLPNLIMEDAELGTHIALLKVRDKDSRHNGEVTC 382
Query: 366 FYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSIS---NDTASINISVED 422
D F + N +++ LD E Y V TD + ++SI + + D
Sbjct: 383 KLEGDVPFKILTSSRNTYKLVTDAVLDREQNPEYNITVTATDRGKPPLSSSSSITLHIGD 442
Query: 423 VNEWEPRFRHPQY 435
VN+ P F Y
Sbjct: 443 VNDNAPVFSQSSY 455
Score = 82.6 bits (195), Expect = 6e-15
Identities = 80/287 (27%), Positives = 122/287 (42%), Gaps = 26/287 (9%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLL---RALDREE 67
I ED +G+ I L V S G++T +L E I+ S+N L LDRE+
Sbjct: 354 IMEDAELGTHIALLKVRDKDSRHNGEVTCKL-EGDVPFKILTSSRNTYKLVTDAVLDREQ 412
Query: 68 KIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXX 127
+ V R S +++ + DVNDNAP + + Y V V+E
Sbjct: 413 N---PEYNITVTATDRGKPPLSSSSSITLHIGDVNDNAPVFSQSSYIVHVAENNPPGASI 469
Query: 128 XXXXXSDRDQPGPHSALHYAVLPGPH-----SEYLGFENELEPIIVVKKPLDFETVNNFT 182
SD D GP+ + Y ++ S Y+ E ++ ++ D E + F
Sbjct: 470 SQVRASDPDL-GPNGQVSYCIMASDLEQRELSSYVSISAE-SGVVFAQRAFDHEQLRAFE 527
Query: 183 IKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHY----TAL---LPDDAEEGTFLT 235
+ L+ +DQGSP L ++ +L+V V D +D P+ Y +AL +P AE G +T
Sbjct: 528 LTLQARDQGSPALSANVSLRVLVDDRNDNAPRVLYPALGPDGSALFDMVPHAAEPGYLVT 587
Query: 236 TSPGPISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQL 281
+ A D D G NA L Y L + TG+V + L
Sbjct: 588 ----KVVAVDADSGHNAWLSYHVLQASEPGLFSLGLRTGEVRTARAL 630
Score = 75.4 bits (177), Expect = 9e-13
Identities = 80/350 (22%), Positives = 146/350 (41%), Gaps = 24/350 (6%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
+ V V D NDNAP + Y V +SE +D+D+ G ++ + ++
Sbjct: 228 IHVLVTDANDNAPVFSQDVYRVSLSENVYPGTTVLQVTATDQDE-GVNAEITFSFSEA-- 284
Query: 154 SEYLGFE-NELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQN 212
S+ F+ N I V LDFE V ++I L +D G + + T++V V+D +D
Sbjct: 285 SQITQFDLNSNTGEITVLNTLDFEEVKEYSIVLEARDGGG--MIAQCTVEVEVIDENDNA 342
Query: 213 PKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHK-QLIVVNKD 271
P+ ++ L+ +DAE GT + + D+D N + GD +++ +++
Sbjct: 343 PEVIFQSLPNLIMEDAELGTHIAL----LKVRDKDSRHNGEVTCKLEGDVPFKILTSSRN 398
Query: 272 TGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQK 331
T ++ L E +P I + AT P + +++ F+Q
Sbjct: 399 TYKLVTDAVLDREQNPEYNITVTATDRGKPPLSSSSSITLHIGDVNDNAPV-----FSQS 453
Query: 332 QYSTTVSEGASPG-SVLLTLTTVPQ---NTEFRESPLQFYVSDRSFLDKFAIN-NAGEVI 386
Y V+E PG S+ + P N + + + R +I+ +G V
Sbjct: 454 SYIVHVAENNPPGASISQVRASDPDLGPNGQVSYCIMASDLEQRELSSYVSISAESGVVF 513
Query: 387 LRRSLDYETTSNYFYQVMVTDSIS---NDTASINISVEDVNEWEPRFRHP 433
+R+ D+E + + D S + S+ + V+D N+ PR +P
Sbjct: 514 AQRAFDHEQLRAFELTLQARDQGSPALSANVSLRVLVDDRNDNAPRVLYP 563
>AF152520-1|AAD43780.1| 803|Homo sapiens protocadherin gamma B4
short form protein protein.
Length = 803
Score = 99 bits (238), Expect = 3e-20
Identities = 103/433 (23%), Positives = 174/433 (40%), Gaps = 22/433 (5%)
Query: 11 ISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEKI 69
I E+ P GS++G L+ + G ++L LR+ + + S L + LDREE
Sbjct: 37 IPEEMPKGSVVGNLATDLGFSVQELPTRKLRVSSEKPYFTVSAESGELLVSSRLDREEIC 96
Query: 70 GPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXX 129
G +P V+V + D+ND+ P++ + +++SE+
Sbjct: 97 GKKPACALEF--EAVAENPLNFYHVNVEIEDINDHTPKFTQNSFELQISESAQPGTRFIL 154
Query: 130 XXXSDRDQPGPHSALHYAVLPGPHSEYLGFENE---LEPIIVVKKPLDFETVNNFTIKLR 186
D D G ++ +Y + P H + E P +V+K PLD E ++ + L
Sbjct: 155 GSAHDADI-GSNTLQNYQLSPSDHFSLINKEKSDGSKYPEMVLKTPLDREKQKSYHLTLT 213
Query: 187 VQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQ 246
D G+PPL S + V V DA+D P F+ + Y L ++ GT + ++A DQ
Sbjct: 214 ALDFGAPPLSSTAQIHVLVTDANDNAPVFSQDVYRVSLSENVYPGTTVL----QVTATDQ 269
Query: 247 DLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYA 305
D G+NA + +S S +N +TG++ L E +IVL+A D A
Sbjct: 270 DEGVNAEITFSFSEASQITQFDLNSNTGEITVLNTLDFEEVKEYSIVLEAR--DGGGMIA 327
Query: 306 LATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQ 365
T+ + + + E A G+ + L +++
Sbjct: 328 QCTVEVEVIDENDNAP-----EVIFQSLPNLIMEDAELGTHIALLKVRDKDSRHNGEVTC 382
Query: 366 FYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSIS---NDTASINISVED 422
D F + N +++ LD E Y V TD + ++SI + + D
Sbjct: 383 KLEGDVPFKILTSSRNTYKLVTDAVLDREQNPEYNITVTATDRGKPPLSSSSSITLHIGD 442
Query: 423 VNEWEPRFRHPQY 435
VN+ P F Y
Sbjct: 443 VNDNAPVFSQSSY 455
Score = 82.6 bits (195), Expect = 6e-15
Identities = 80/287 (27%), Positives = 122/287 (42%), Gaps = 26/287 (9%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLL---RALDREE 67
I ED +G+ I L V S G++T +L E I+ S+N L LDRE+
Sbjct: 354 IMEDAELGTHIALLKVRDKDSRHNGEVTCKL-EGDVPFKILTSSRNTYKLVTDAVLDREQ 412
Query: 68 KIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXX 127
+ V R S +++ + DVNDNAP + + Y V V+E
Sbjct: 413 N---PEYNITVTATDRGKPPLSSSSSITLHIGDVNDNAPVFSQSSYIVHVAENNPPGASI 469
Query: 128 XXXXXSDRDQPGPHSALHYAVLPGPH-----SEYLGFENELEPIIVVKKPLDFETVNNFT 182
SD D GP+ + Y ++ S Y+ E ++ ++ D E + F
Sbjct: 470 SQVRASDPDL-GPNGQVSYCIMASDLEQRELSSYVSISAE-SGVVFAQRAFDHEQLRAFE 527
Query: 183 IKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHY----TAL---LPDDAEEGTFLT 235
+ L+ +DQGSP L ++ +L+V V D +D P+ Y +AL +P AE G +T
Sbjct: 528 LTLQARDQGSPALSANVSLRVLVDDRNDNAPRVLYPALGPDGSALFDMVPHAAEPGYLVT 587
Query: 236 TSPGPISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQL 281
+ A D D G NA L Y L + TG+V + L
Sbjct: 588 ----KVVAVDADSGHNAWLSYHVLQASEPGLFSLGLRTGEVRTARAL 630
Score = 75.4 bits (177), Expect = 9e-13
Identities = 80/350 (22%), Positives = 146/350 (41%), Gaps = 24/350 (6%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
+ V V D NDNAP + Y V +SE +D+D+ G ++ + ++
Sbjct: 228 IHVLVTDANDNAPVFSQDVYRVSLSENVYPGTTVLQVTATDQDE-GVNAEITFSFSEA-- 284
Query: 154 SEYLGFE-NELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQN 212
S+ F+ N I V LDFE V ++I L +D G + + T++V V+D +D
Sbjct: 285 SQITQFDLNSNTGEITVLNTLDFEEVKEYSIVLEARDGGG--MIAQCTVEVEVIDENDNA 342
Query: 213 PKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHK-QLIVVNKD 271
P+ ++ L+ +DAE GT + + D+D N + GD +++ +++
Sbjct: 343 PEVIFQSLPNLIMEDAELGTHIAL----LKVRDKDSRHNGEVTCKLEGDVPFKILTSSRN 398
Query: 272 TGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQK 331
T ++ L E +P I + AT P + +++ F+Q
Sbjct: 399 TYKLVTDAVLDREQNPEYNITVTATDRGKPPLSSSSSITLHIGDVNDNAPV-----FSQS 453
Query: 332 QYSTTVSEGASPG-SVLLTLTTVPQ---NTEFRESPLQFYVSDRSFLDKFAIN-NAGEVI 386
Y V+E PG S+ + P N + + + R +I+ +G V
Sbjct: 454 SYIVHVAENNPPGASISQVRASDPDLGPNGQVSYCIMASDLEQRELSSYVSISAESGVVF 513
Query: 387 LRRSLDYETTSNYFYQVMVTDSIS---NDTASINISVEDVNEWEPRFRHP 433
+R+ D+E + + D S + S+ + V+D N+ PR +P
Sbjct: 514 AQRAFDHEQLRAFELTLQARDQGSPALSANVSLRVLVDDRNDNAPRVLYP 563
>AF152333-1|AAD43727.1| 923|Homo sapiens protocadherin gamma B4
protein.
Length = 923
Score = 99 bits (238), Expect = 3e-20
Identities = 103/433 (23%), Positives = 174/433 (40%), Gaps = 22/433 (5%)
Query: 11 ISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEKI 69
I E+ P GS++G L+ + G ++L LR+ + + S L + LDREE
Sbjct: 37 IPEEMPKGSVVGNLATDLGFSVQELPTRKLRVSSEKPYFTVSAESGELLVSSRLDREEIC 96
Query: 70 GPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXX 129
G +P V+V + D+ND+ P++ + +++SE+
Sbjct: 97 GKKPACALEF--EAVAENPLNFYHVNVEIEDINDHTPKFTQNSFELQISESAQPGTRFIL 154
Query: 130 XXXSDRDQPGPHSALHYAVLPGPHSEYLGFENE---LEPIIVVKKPLDFETVNNFTIKLR 186
D D G ++ +Y + P H + E P +V+K PLD E ++ + L
Sbjct: 155 GSAHDADI-GSNTLQNYQLSPSDHFSLINKEKSDGSKYPEMVLKTPLDREKQKSYHLTLT 213
Query: 187 VQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQ 246
D G+PPL S + V V DA+D P F+ + Y L ++ GT + ++A DQ
Sbjct: 214 ALDFGAPPLSSTAQIHVLVTDANDNAPVFSQDVYRVSLSENVYPGTTVL----QVTATDQ 269
Query: 247 DLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYA 305
D G+NA + +S S +N +TG++ L E +IVL+A D A
Sbjct: 270 DEGVNAEITFSFSEASQITQFDLNSNTGEITVLNTLDFEEVKEYSIVLEAR--DGGGMIA 327
Query: 306 LATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQ 365
T+ + + + E A G+ + L +++
Sbjct: 328 QCTVEVEVIDENDNAP-----EVIFQSLPNLIMEDAELGTHIALLKVRDKDSRHNGEVTC 382
Query: 366 FYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSIS---NDTASINISVED 422
D F + N +++ LD E Y V TD + ++SI + + D
Sbjct: 383 KLEGDVPFKILTSSRNTYKLVTDAVLDREQNPEYNITVTATDRGKPPLSSSSSITLHIGD 442
Query: 423 VNEWEPRFRHPQY 435
VN+ P F Y
Sbjct: 443 VNDNAPVFSQSSY 455
Score = 82.6 bits (195), Expect = 6e-15
Identities = 80/287 (27%), Positives = 122/287 (42%), Gaps = 26/287 (9%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLL---RALDREE 67
I ED +G+ I L V S G++T +L E I+ S+N L LDRE+
Sbjct: 354 IMEDAELGTHIALLKVRDKDSRHNGEVTCKL-EGDVPFKILTSSRNTYKLVTDAVLDREQ 412
Query: 68 KIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXX 127
+ V R S +++ + DVNDNAP + + Y V V+E
Sbjct: 413 N---PEYNITVTATDRGKPPLSSSSSITLHIGDVNDNAPVFSQSSYIVHVAENNPPGASI 469
Query: 128 XXXXXSDRDQPGPHSALHYAVLPGPH-----SEYLGFENELEPIIVVKKPLDFETVNNFT 182
SD D GP+ + Y ++ S Y+ E ++ ++ D E + F
Sbjct: 470 SQVRASDPDL-GPNGQVSYCIMASDLEQRELSSYVSISAE-SGVVFAQRAFDHEQLRAFE 527
Query: 183 IKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHY----TAL---LPDDAEEGTFLT 235
+ L+ +DQGSP L ++ +L+V V D +D P+ Y +AL +P AE G +T
Sbjct: 528 LTLQARDQGSPALSANVSLRVLVDDRNDNAPRVLYPALGPDGSALFDMVPHAAEPGYLVT 587
Query: 236 TSPGPISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQL 281
+ A D D G NA L Y L + TG+V + L
Sbjct: 588 ----KVVAVDADSGHNAWLSYHVLQASEPGLFSLGLRTGEVRTARAL 630
Score = 75.4 bits (177), Expect = 9e-13
Identities = 80/350 (22%), Positives = 146/350 (41%), Gaps = 24/350 (6%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
+ V V D NDNAP + Y V +SE +D+D+ G ++ + ++
Sbjct: 228 IHVLVTDANDNAPVFSQDVYRVSLSENVYPGTTVLQVTATDQDE-GVNAEITFSFSEA-- 284
Query: 154 SEYLGFE-NELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQN 212
S+ F+ N I V LDFE V ++I L +D G + + T++V V+D +D
Sbjct: 285 SQITQFDLNSNTGEITVLNTLDFEEVKEYSIVLEARDGGG--MIAQCTVEVEVIDENDNA 342
Query: 213 PKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHK-QLIVVNKD 271
P+ ++ L+ +DAE GT + + D+D N + GD +++ +++
Sbjct: 343 PEVIFQSLPNLIMEDAELGTHIAL----LKVRDKDSRHNGEVTCKLEGDVPFKILTSSRN 398
Query: 272 TGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQK 331
T ++ L E +P I + AT P + +++ F+Q
Sbjct: 399 TYKLVTDAVLDREQNPEYNITVTATDRGKPPLSSSSSITLHIGDVNDNAPV-----FSQS 453
Query: 332 QYSTTVSEGASPG-SVLLTLTTVPQ---NTEFRESPLQFYVSDRSFLDKFAIN-NAGEVI 386
Y V+E PG S+ + P N + + + R +I+ +G V
Sbjct: 454 SYIVHVAENNPPGASISQVRASDPDLGPNGQVSYCIMASDLEQRELSSYVSISAESGVVF 513
Query: 387 LRRSLDYETTSNYFYQVMVTDSIS---NDTASINISVEDVNEWEPRFRHP 433
+R+ D+E + + D S + S+ + V+D N+ PR +P
Sbjct: 514 AQRAFDHEQLRAFELTLQARDQGSPALSANVSLRVLVDDRNDNAPRVLYP 563
>AY010111-1|AAG27034.2| 3354|Homo sapiens cadherin 23 protein.
Length = 3354
Score = 99.5 bits (237), Expect = 5e-20
Identities = 96/369 (26%), Positives = 156/369 (42%), Gaps = 28/369 (7%)
Query: 80 CDRRRTTDP-SFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQP 138
C R R P S + V +RV D+NDN P P + +SE SD D
Sbjct: 1822 CARDRGMPPLSSTMLVGIRVLDINDNDPVLLNLPMNITISENSPVSSFVAHVLASDADS- 1880
Query: 139 GPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYS- 197
G ++ L + + G + E F N I+ V +PLD E + + + + V+D P +
Sbjct: 1881 GCNARLTFNITAG-NRERAFFINATTGIVTVNRPLDRERIPEYKLTISVKDNPENPRIAR 1939
Query: 198 -DTTLQVTVL-DADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQ 255
D L + L D +D +P FT Y A + +++ GT LT GPI A D D I A +
Sbjct: 1940 RDYDLLLIFLSDENDNHPLFTKSTYQAEVMENSPAGTPLTVLNGPILALDADQDIYAVVT 1999
Query: 256 YSSTGDHKQLIVVNKDTGQVAATKQLIAELD----PSVTIVLKATQVD--NPDRYALATL 309
Y G L +N TG V +I + + P + ++L A + N + L T+
Sbjct: 2000 YQLLGAQSGLFDINSSTGVVTVRSGVIIDREAFSPPILELLLLAEDIGLLNSTAHLLITI 2059
Query: 310 XXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVS 369
F+ + + E PG +L +T +++ + Y
Sbjct: 2060 LDDNDNRPT---------FSPATLTVHLLENCPPGFSVLQVTATDEDSGLNGELV--YRI 2108
Query: 370 DRSFLDKFAINNAGEVIL--RRSLDYETTSNYFYQVMVTDSIS---NDTASINISVEDVN 424
+ D+F I+ VI ++D E +Y V+ TD + + TA + I ++D+N
Sbjct: 2109 EAGAQDRFLIHLVTGVIRVGNATIDREEQESYRLTVVATDRGTVPLSGTAIVTILIDDIN 2168
Query: 425 EWEPRFRHP 433
+ P F +P
Sbjct: 2169 DSRPEFLNP 2177
Score = 94.3 bits (224), Expect = 2e-18
Identities = 102/417 (24%), Positives = 179/417 (42%), Gaps = 26/417 (6%)
Query: 28 GDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEKIGPSNVYVNVRCDRRRTTD 87
G ++D D + QE AV I GS ++++ E + V ++V + +
Sbjct: 2213 GIVAKDDTDRLVPNQEDAFAVNINTGS---VMVKSPMNRELVATYEVTLSVIDNASDLPE 2269
Query: 88 PSFVIP---VSVRVWDVNDNAPQWE--GAPYAV-RVSETXXXXXXXXXXXXSDRDQPGPH 141
S +P ++V V DVNDN PQ++ G Y + R+ E D D+ G +
Sbjct: 2270 RSVSVPNAKLTVNVLDVNDNTPQFKPFGITYYMERILEGATPGTTLIAVAAVDPDK-GLN 2328
Query: 142 SALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTL 201
+ Y +L Y+ E+ ++ + +D+E V+ +R D GSPP ++ +
Sbjct: 2329 GLVTYTLLDLVPPGYVQLEDSSAGKVIANRTVDYEEVHWLNFTVRASDNGSPPRAAEIPV 2388
Query: 202 QVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGD 261
+ ++D +D NP F Y + +D GT + T ++A D D G A ++Y S GD
Sbjct: 2389 YLEIVDINDNNPIFDQPSYQEAVFEDVPVGTIILT----VTATDADSGNFALIEY-SLGD 2443
Query: 262 HKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNP-DRYALATLXXXXXXXXXXX 320
+ +N TG + L + + +L A DNP D +
Sbjct: 2444 GESKFAINPTTGDIYVLSSL--DREKKDHYILTALAKDNPGDVASNRRENSVQVVIQVLD 2501
Query: 321 XXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAIN 380
QF++ Q+ST+V E G+ ++T+ Q+ E L Y + ++ F ++
Sbjct: 2502 VNDCRPQFSKPQFSTSVYENEPAGTSVITMMATDQD-EGPNGELT-YSLEGPGVEAFHVD 2559
Query: 381 -NAGEVILRRSLDYETTSNYFYQVMVTDSISN---DTASINISVEDVNEWEPRFRHP 433
++G V +R L ++ + V+ TD T + + V DVN+ P F P
Sbjct: 2560 MDSGLVTTQRPL--QSYEKFSLTVVATDGGEPPLWGTTMLLVEVIDVNDNRPVFVRP 2614
Score = 92.7 bits (220), Expect = 5e-18
Identities = 101/454 (22%), Positives = 197/454 (43%), Gaps = 42/454 (9%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEK-- 68
+ ED P+G+II T++ S + I L + + I P + ++ +L +LDRE+K
Sbjct: 2411 VFEDVPVGTIILTVTATDADSGNFALIEYSLGDGESKFAINPTTGDIYVLSSLDREKKDH 2470
Query: 69 -----IGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXX 123
+ N +V +RR + + V ++V DVND PQ+ ++ V E
Sbjct: 2471 YILTALAKDNP-GDVASNRRENS-----VQVVIQVLDVNDCRPQFSKPQFSTSVYENEPA 2524
Query: 124 XXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTI 183
+D+D+ GP+ L Y+ L GP E + + ++ ++PL ++ F++
Sbjct: 2525 GTSVITMMATDQDE-GPNGELTYS-LEGPGVEAFHVDMD-SGLVTTQRPL--QSYEKFSL 2579
Query: 184 KLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISA 243
+ D G PPL+ T L V V+D +D P F +L E L ++ + A
Sbjct: 2580 TVVATDGGEPPLWGTTMLLVEVIDVNDNRPVFVRPPNGTIL--HIREEIPLRSNVYEVYA 2637
Query: 244 ADQDLGINAPLQYS--STGDHK--QLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVD 299
D+D G+N ++YS T ++ + +++ +G + ++L E +++L A+ +
Sbjct: 2638 TDKDEGLNGAVRYSFLKTAGNRDWEFFIIDPISGLIQTAQRLDRESQAVYSLILVASDLG 2697
Query: 300 NPDRY-ALATLXXXXXXXXXXXXXXXXLQFTQKQYS-TTVSEGASPGSVLLTLTTVPQNT 357
P Y + L QY TV E + G+++ +T
Sbjct: 2698 QPVPYETMQPLQVALEDIDDNEPLFVRPPKGSPQYQLLTVPEHSPRGTLVGNVTGAVDAD 2757
Query: 358 EFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVT----------- 406
E + + ++++ + F + G +++ R LD E + + + V +
Sbjct: 2758 EGPNAIVYYFIAAGNEEKNFHLQPDGCLLVLRDLDREREAIFSFIVKASSNRSWTPPRGP 2817
Query: 407 ----DSISNDT-ASINISVEDVNEWEPRFRHPQY 435
D +++ T + + +ED+N+ PRF +Y
Sbjct: 2818 SPTLDLVADLTLQEVRVVLEDINDQPPRFTKAEY 2851
Score = 92.3 bits (219), Expect = 7e-18
Identities = 102/440 (23%), Positives = 179/440 (40%), Gaps = 31/440 (7%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEKIG 70
ISEDTP+GS + L D D + +E + P + + L + LDRE K
Sbjct: 42 ISEDTPVGSSVTQLLAQ-DMDNDPLVFGVSGEEASRFFAVEPDTGVVWLRQPLDRETK-- 98
Query: 71 PSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXX 130
S V + V+++V DVNDNAP + PY+VR+ E
Sbjct: 99 -SEFTVEFSVSDHQGV---ITRKVNIQVGDVNDNAPTFHNQPYSVRIPENTPVGTPIFIV 154
Query: 131 XXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQ 190
+D D S L+ P S++ ++ I+ V + LD+ET + + + DQ
Sbjct: 155 NATDPDLGAGGSVLYSF---QPPSQFFAIDS-ARGIVTVIRELDYETTQAYQLTVNATDQ 210
Query: 191 G-SPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLG 249
+ PL + L + + D D +P F Y+ + + + GT + I+A DQD G
Sbjct: 211 DKTRPLSTLANLAIIITDVQDMDPIFINLPYSTNIYEHSPPGTTVRI----ITAIDQDKG 266
Query: 250 INAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAE---LDPSVTIVLKATQVDNPDRYA 305
+ Y+ +G+ + ++ +G + L E + +K T++ N DR
Sbjct: 267 RPRGIGYTIVSGNTNSIFALDYISGVLTLNGLLDRENPLYSHGFILTVKGTEL-NDDRTP 325
Query: 306 LATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVL-LTLTTVPQNTEF-RESP 363
+F +YS ++E A G L L + V ++ S
Sbjct: 326 SDATVTTTFNILVIDINDNAPEFNSSEYSVAITELAQVGFALPLFIQVVDKDENLGLNSM 385
Query: 364 LQFYV----SDRSFLDKFAINNAGEVILRRS--LDYETTSNYFYQVMVTDSISNDT--AS 415
+ Y+ S + ++ ++ +R + LDYET Y + + +S+ + A
Sbjct: 386 FEVYLVGNNSHHFIISPTSVQGKADIRIRVAIPLDYETVDRYDFDLFANESVPDHVGYAK 445
Query: 416 INISVEDVNEWEPRFRHPQY 435
+ I++ + N+ P F P Y
Sbjct: 446 VKITLINENDNRPIFSQPLY 465
Score = 84.2 bits (199), Expect = 2e-15
Identities = 105/449 (23%), Positives = 173/449 (38%), Gaps = 31/449 (6%)
Query: 91 VIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLP 150
+ V++ + D+NDN P W+ APY + + E D D G + L Y++ P
Sbjct: 761 IATVNITLLDINDNHPTWKDAPYYINLVEMTPPDSDVTTVVAVDPDL-GENGTLVYSIQP 819
Query: 151 GPHSEY-----LGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPL--YSDTTLQV 203
P+ Y G ++ + P E I + V D G PPL S T+ V
Sbjct: 820 -PNKFYSLNSTTGKIRTTHAMLDRENPDPHEAELMRKIVVSVTDCGRPPLKATSSATVFV 878
Query: 204 TVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQY-SSTGDH 262
+LD +D +P F + A + EG S + A D D G+N + Y G
Sbjct: 879 NLLDLNDNDPTFQNLPFVA----EVLEGIPAGVSIYQVVAIDLDEGLNGLVSYRMPVGMP 934
Query: 263 KQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXX 322
+ ++N +G V T +L E + + A+ P + + +TL
Sbjct: 935 RMDFLINSSSGVVVTTTELDRERIAEYQLRVVASDAGTPTKSSTSTLTIHVLDVNDETPT 994
Query: 323 XXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAINNA 382
F Y+ +VSE P + N + L ++++ + KF++
Sbjct: 995 -----FFPAVYNVSVSEDV-PREFRVVWLNCTDNDVGLNAELSYFITGGNVDGKFSVGYR 1048
Query: 383 GEVILR-RSLDYETTSNYFYQVMVTDS-----ISNDTASINISVEDVNEWEPRFRHPQYE 436
V+ LD ETT+ Y + D+ TA++ ++V DVN+ P F YE
Sbjct: 1049 DAVVRTVVGLDRETTAAYMLILEAIDNGPVGKRHTGTATVFVTVLDVNDNRPIFLQSSYE 1108
Query: 437 FEXXXXXXXXXXXXXXXXXXXXVAHDGDAGTLALS-LAGQHARMFYINASGDLFLR-EEA 494
A +G+ G + L G H F I+ S L +R
Sbjct: 1109 ---ASVPEDIPEGHSILQLKATDADEGEFGRVWYRILHGNHGNNFRIHVSNGLLMRGPRP 1165
Query: 495 IGNLNSSSLHLVATAIDSGIPPRQTSVPV 523
+ +SS L+ A + + P ++SV V
Sbjct: 1166 LDRERNSSHVLIVEAYNHDLGPMRSSVRV 1194
Score = 82.6 bits (195), Expect = 6e-15
Identities = 104/480 (21%), Positives = 181/480 (37%), Gaps = 33/480 (6%)
Query: 57 LTLLRALDREEKIGPSNVYVNVRC----DRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAP 112
LTL LDRE + + V+ D R +D + ++ V D+NDNAP++ +
Sbjct: 293 LTLNGLLDRENPLYSHGFILTVKGTELNDDRTPSDATVTTTFNILVIDINDNAPEFNSSE 352
Query: 113 YAVRVSETXXXXXXX-XXXXXSDRDQPGPHSALHYAVLPGPHSEYL-----GFENELEPI 166
Y+V ++E D+D+ +++ L G +S + + + +
Sbjct: 353 YSVAITELAQVGFALPLFIQVVDKDENLGLNSMFEVYLVGNNSHHFIISPTSVQGKADIR 412
Query: 167 IVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPD 226
I V PLD+ETV+ + L ++ P +++T+++ +D P F+ Y L +
Sbjct: 413 IRVAIPLDYETVDRYDFDL-FANESVPDHVGYAKVKITLINENDNRPIFSQPLYNISLYE 471
Query: 227 DAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLIAELD 286
+ GT + T + A D D G + Y + D + + +KDTG + +L EL
Sbjct: 472 NVTVGTSVLT----VLATDNDAGTFGEVSYFFSDDPDRFSL-DKDTGLIMLIARLDYELI 526
Query: 287 PSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSV 346
T+ + A + + F + Y + E +
Sbjct: 527 QRFTLTIIARDGGGEETTGRVRINVLDVNDNVPT-------FQKDAYVGALRENEPSVTQ 579
Query: 347 LLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAIN---NAGEVILRRSLDYETTSN--YFY 401
L+ L +++ VS +F F I+ G + + R LDYE SN +
Sbjct: 580 LVRLRATDEDSPPNNQITYSIVSASAFGSYFDISLYEGYGVISVSRPLDYEQISNGLIYL 639
Query: 402 QVMVTDSIS---NDTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXX 458
VM D+ + N T + I V D N+ P F P Y
Sbjct: 640 TVMAMDAGNPPLNSTVPVTIEVFDENDNPPTFSKPAYFVSVVENIMAGATVLFLNATDLD 699
Query: 459 VAHDGDAGTLALSLAGQHARMFYINASGDLFLREEAIGNLNSSSLHLVATAIDSGIPPRQ 518
+ + ++ SL G + F INA + S L+ A+D G+ Q
Sbjct: 700 RSREYGQESIIYSLEG--STQFRINARSGEITTTSLLDRETKSEYILIVRAVDGGVGHNQ 757
Score = 81.0 bits (191), Expect = 2e-14
Identities = 113/480 (23%), Positives = 186/480 (38%), Gaps = 47/480 (9%)
Query: 63 LDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXX 122
+DREE+ + + V R T S V++ + D+ND+ P++ V V E+
Sbjct: 2132 IDREEQ---ESYRLTVVATDRGTVPLSGTAIVTILIDDINDSRPEFLNPIQTVSVLESAE 2188
Query: 123 XXXXXXXXXXSDRDQPGPHSALHYAVLPG--------PHSEYLGFENELEPIIVVKKPLD 174
D D P H + P+ E N ++VK P++
Sbjct: 2189 PGTVIANITAIDHDL-NPKLEYHIVGIVAKDDTDRLVPNQEDAFAVNINTGSVMVKSPMN 2247
Query: 175 FETVNNFTIKLRVQDQGSP-PLYS----DTTLQVTVLDADDQNPKFT---YEHYTALLPD 226
E V + + L V D S P S + L V VLD +D P+F +Y + +
Sbjct: 2248 RELVATYEVTLSVIDNASDLPERSVSVPNAKLTVNVLDVNDNTPQFKPFGITYYMERILE 2307
Query: 227 DAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDT--GQVAATKQLIAE 284
A GT L ++A D D G+N + Y+ V +D+ G+V A + + E
Sbjct: 2308 GATPGTTLIA----VAAVDPDKGLNGLVTYTLLDLVPPGYVQLEDSSAGKVIANRTVDYE 2363
Query: 285 LDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPG 344
+ ++A+ +P R A + F Q Y V E G
Sbjct: 2364 EVHWLNFTVRASDNGSPPRAAEIPVYLEIVDINDNNPI-----FDQPSYQEAVFEDVPVG 2418
Query: 345 SVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQV 403
+++LT+T ++ + +++ + D KFAIN G++ + SLD E +Y
Sbjct: 2419 TIILTVTATDADSG-NFALIEYSLGDGE--SKFAINPTTGDIYVLSSLDREKKDHYILTA 2475
Query: 404 MVTDS----ISN---DTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXX 456
+ D+ SN ++ + I V DVN+ P+F PQ+
Sbjct: 2476 LAKDNPGDVASNRRENSVQVVIQVLDVNDCRPQFSKPQFSTSVYENEPAGTSVITMMATD 2535
Query: 457 XXVAHDGDAGTLALSLAGQHARMFYINASGDLFLREEAIGNLNSSSLHLVATAIDSGIPP 516
+G G L SL G F+++ L + + + SL +VAT D G PP
Sbjct: 2536 QD---EGPNGELTYSLEGPGVEAFHVDMDSGLVTTQRPLQSYEKFSLTVVAT--DGGEPP 2590
Score = 78.6 bits (185), Expect = 9e-14
Identities = 88/354 (24%), Positives = 153/354 (43%), Gaps = 31/354 (8%)
Query: 94 VSVRVWDVNDNAP----QWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVL 149
V V V D+NDN P +EG P+ V + DRD GP+ + Y+++
Sbjct: 1730 VLVNVNDINDNVPTFPRDYEG-PFEVTEGQPGPRVWTFLAH---DRDS-GPNGQVEYSIM 1784
Query: 150 PG-PHSEYLGFENELEPIIVVKKP--LDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVL 206
G P E++ + +E ++ V+K LD ET+ + + + +D+G PPL S + + VL
Sbjct: 1785 DGDPLGEFV--ISPVEGVLRVRKDVELDRETIAFYNLTICARDRGMPPLSSTMLVGIRVL 1842
Query: 207 DADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSST-GDHKQL 265
D +D +P + +++ +F+ + A+D D G NA L ++ T G+ ++
Sbjct: 1843 DINDNDPVLLNLPMNITISENSPVSSFV----AHVLASDADSGCNARLTFNITAGNRERA 1898
Query: 266 IVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXX 325
+N TG V + L E P + + DNP+ +A
Sbjct: 1899 FFINATTGIVTVNRPLDRERIPEYKLTISVK--DNPENPRIARRDYDLLLIFLSDENDNH 1956
Query: 326 LQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDR---SFLDKFAINNA 382
FT+ Y V E SP LT+ P + + V+ + + F IN++
Sbjct: 1957 PLFTKSTYQAEVMEN-SPAGTPLTVLNGPILALDADQDIYAVVTYQLLGAQSGLFDINSS 2015
Query: 383 GEVILRRS---LDYETTSNYFYQVMVTD---SISNDTASINISVEDVNEWEPRF 430
V+ RS +D E S ++++ + N TA + I++ D N+ P F
Sbjct: 2016 TGVVTVRSGVIIDREAFSPPILELLLLAEDIGLLNSTAHLLITILDDNDNRPTF 2069
Score = 77.0 bits (181), Expect = 3e-13
Identities = 81/352 (23%), Positives = 144/352 (40%), Gaps = 24/352 (6%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPG-P 152
V V + D+NDN P ++ P+ V E D D+ G + + Y + G P
Sbjct: 876 VFVNLLDLNDNDPTFQNLPFVAEVLEGIPAGVSIYQVVAIDLDE-GLNGLVSYRMPVGMP 934
Query: 153 HSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQN 212
++L N ++V LD E + + +++ D G+P S +TL + VLD +D+
Sbjct: 935 RMDFL--INSSSGVVVTTTELDRERIAEYQLRVVASDAGTPTKSSTSTLTIHVLDVNDET 992
Query: 213 PKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQ-LIVVNKD 271
P F Y + +D + ++ D D+G+NA L Y TG + V
Sbjct: 993 PTFFPAVYNVSVSEDVPREFRVVW----LNCTDNDVGLNAELSYFITGGNVDGKFSVGYR 1048
Query: 272 TGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQK 331
V L E + ++L+A +DN T + F Q
Sbjct: 1049 DAVVRTVVGLDRETTAAYMLILEA--IDNGPVGKRHTGTATVFVTVLDVNDNRPI-FLQS 1105
Query: 332 QYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILR--R 389
Y +V E G +L L + E + + + + + F I+ + +++R R
Sbjct: 1106 SYEASVPEDIPEGHSILQLKATDAD-EGEFGRVWYRILHGNHGNNFRIHVSNGLLMRGPR 1164
Query: 390 SLDYETTSNYFYQVMVTDSISND------TASINISVEDVNEWEPRFRHPQY 435
LD E S++ V++ ++ ++D + + + VED+N+ P F QY
Sbjct: 1165 PLDRERNSSH---VLIVEAYNHDLGPMRSSVRVIVYVEDINDEAPVFTQQQY 1213
Score = 74.1 bits (174), Expect = 2e-12
Identities = 83/355 (23%), Positives = 153/355 (43%), Gaps = 28/355 (7%)
Query: 92 IPVSVRVWDVNDNAPQWE-GAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLP 150
+ V + V D NDN+P+++ + AV + E D D G + + +++
Sbjct: 1402 VKVYITVLDENDNSPRFDFTSDSAVSIPEDCPVGQRVATVKAWDPDA-GSNGQVVFSLAS 1460
Query: 151 GPHSEYLGFENELEPI--IVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDA 208
G + + I + V +PLD E ++++ +++ D+G+PP D LQVT+LD
Sbjct: 1461 GNIAGAFEIVTTNDSIGEVFVARPLDREELDHYILQVVASDRGTPPRKKDHILQVTILDI 1520
Query: 209 DDQNPKFTYEH-YTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIV 267
+D P Y + ++ GT + + A D+D+GIN+ L Y T +K +
Sbjct: 1521 NDNPPVIESPFGYNVSVNENVGGGTAVV----QVRATDRDIGINSVLSYYITEGNKDMTF 1576
Query: 268 -VNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXL 326
+++ +G++ AT+ + + L AT D AT
Sbjct: 1577 RMDRISGEI-ATRPAPPDRERQSFYHLVATVEDEGTPTLSAT---THVYVTIVDENDNAP 1632
Query: 327 QFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESP---LQFYVSDRSFLDKFAIN-NA 382
F Q Y + EG P ++ +L T+ Q + E P + + + + ++ F I+ +
Sbjct: 1633 MFQQPHYEVLLDEG--PDTLNTSLITI-QALDLDEGPNGTVTYAIVAGNIVNTFRIDRHM 1689
Query: 383 GEVILRRSLDYETT-SNYFYQVMVTDSIS------NDTASINISVEDVNEWEPRF 430
G + + LDYE + Y V TD T ++ ++V D+N+ P F
Sbjct: 1690 GVITAAKELDYEISHGRYTLIVTATDQCPILSHRLTSTTTVLVNVNDINDNVPTF 1744
Score = 70.1 bits (164), Expect = 3e-11
Identities = 82/363 (22%), Positives = 148/363 (40%), Gaps = 33/363 (9%)
Query: 96 VRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSE 155
+ + D NDN P + A V + E +D D G + L Y + G
Sbjct: 2057 ITILDDNDNRPTFSPATLTVHLLENCPPGFSVLQVTATDEDS-GLNGELVYRIEAGAQDR 2115
Query: 156 YLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKF 215
+L I V +D E ++ + + D+G+ PL + + + D +D P+F
Sbjct: 2116 FL-IHLVTGVIRVGNATIDREEQESYRLTVVATDRGTVPLSGTAIVTILIDDINDSRPEF 2174
Query: 216 TYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTG-----DHKQLI---- 266
T + + AE GT + I+A D DL N L+Y G D +L+
Sbjct: 2175 LNPIQTVSVLESAEPGTVIAN----ITAIDHDL--NPKLEYHIVGIVAKDDTDRLVPNQE 2228
Query: 267 ---VVNKDTGQVAA----TKQLIAELDPSVTIVLKATQVDNPDR-YALATLXXXXXXXXX 318
VN +TG V ++L+A + +++++ A+ D P+R ++
Sbjct: 2229 DAFAVNINTGSVMVKSPMNRELVATYEVTLSVIDNAS--DLPERSVSVPNAKLTVNVLDV 2286
Query: 319 XXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSD--RSFLDK 376
F Y + EGA+PG+ L+ + V + + + + D +
Sbjct: 2287 NDNTPQFKPFGITYYMERILEGATPGTTLIAVAAVDPDKGL-NGLVTYTLLDLVPPGYVQ 2345
Query: 377 FAINNAGEVILRRSLDYETTSNYFYQVMVTDSISNDTAS---INISVEDVNEWEPRFRHP 433
++AG+VI R++DYE + V +D+ S A+ + + + D+N+ P F P
Sbjct: 2346 LEDSSAGKVIANRTVDYEEVHWLNFTVRASDNGSPPRAAEIPVYLEIVDINDNNPIFDQP 2405
Query: 434 QYE 436
Y+
Sbjct: 2406 SYQ 2408
Score = 66.5 bits (155), Expect = 4e-10
Identities = 83/392 (21%), Positives = 146/392 (37%), Gaps = 17/392 (4%)
Query: 48 VGIVPGSKNLTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQ 107
+ + G +++ R LD E+ I +Y+ V + +PV++ V+D NDN P
Sbjct: 612 ISLYEGYGVISVSRPLDYEQ-ISNGLIYLTVMAMDAGNPPLNSTVPVTIEVFDENDNPPT 670
Query: 108 WEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPII 167
+ Y V V E +D D+ + +++ N I
Sbjct: 671 FSKPAYFVSVVENIMAGATVLFLNATDLDRSREYG--QESIIYSLEGSTQFRINARSGEI 728
Query: 168 VVKKPLDFETVNNFTIKLRVQD--QGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLP 225
LD ET + + + +R D G T+ +T+LD +D +P + Y L
Sbjct: 729 TTTSLLDRETKSEYILIVRAVDGGVGHNQKTGIATVNITLLDINDNHPTWKDAPYYINLV 788
Query: 226 DDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLI--A 283
+ + +TT + A D DLG N L YS +K +N TG++ T ++
Sbjct: 789 EMTPPDSDVTT----VVAVDPDLGENGTLVYSIQPPNK-FYSLNSTTGKIRTTHAMLDRE 843
Query: 284 ELDPSVTIVLKATQVDNPD--RYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGA 341
DP +++ V D R L F + V EG
Sbjct: 844 NPDPHEAELMRKIVVSVTDCGRPPLKATSSATVFVNLLDLNDNDPTFQNLPFVAEVLEGI 903
Query: 342 SPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFY 401
G + + + + +D +++G V+ LD E + Y
Sbjct: 904 PAGVSIYQVVAIDLDEGLNGLVSYRMPVGMPRMDFLINSSSGVVVTTTELDRERIAEYQL 963
Query: 402 QVMVTDS---ISNDTASINISVEDVNEWEPRF 430
+V+ +D+ + T+++ I V DVN+ P F
Sbjct: 964 RVVASDAGTPTKSSTSTLTIHVLDVNDETPTF 995
Score = 64.1 bits (149), Expect = 2e-09
Identities = 53/222 (23%), Positives = 94/222 (42%), Gaps = 10/222 (4%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVL-PGP 152
V + V DVNDN P ++ Y + E +D D P P++ + Y+++
Sbjct: 547 VRINVLDVNDNVPTFQKDAYVGALRENEPSVTQLVRLRATDEDSP-PNNQITYSIVSASA 605
Query: 153 HSEYLGFE-NELEPIIVVKKPLDFETVNNFTIKLRV--QDQGSPPLYSDTTLQVTVLDAD 209
Y E +I V +PLD+E ++N I L V D G+PPL S + + V D +
Sbjct: 606 FGSYFDISLYEGYGVISVSRPLDYEQISNGLIYLTVMAMDAGNPPLNSTVPVTIEVFDEN 665
Query: 210 DQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVN 269
D P F+ Y + ++ G + ++ G + YS G + +N
Sbjct: 666 DNPPTFSKPAYFVSVVENIMAGATVLFLNATDLDRSREYG-QESIIYSLEGSTQ--FRIN 722
Query: 270 KDTGQVAATKQLIAELDPSVTIVLKATQ--VDNPDRYALATL 309
+G++ T L E ++++A V + + +AT+
Sbjct: 723 ARSGEITTTSLLDRETKSEYILIVRAVDGGVGHNQKTGIATV 764
Score = 62.1 bits (144), Expect = 9e-09
Identities = 90/364 (24%), Positives = 150/364 (41%), Gaps = 28/364 (7%)
Query: 85 TTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSAL 144
T S +++ V DVND P + A Y V VSE +D D G ++ L
Sbjct: 972 TPTKSSTSTLTIHVLDVNDETPTFFPAVYNVSVSEDVPREFRVVWLNCTDND-VGLNAEL 1030
Query: 145 HYAVLPG--PHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGS-PPLYSDT-T 200
Y + G +G+ + + +V LD ET + + L D G ++ T T
Sbjct: 1031 SYFITGGNVDGKFSVGYRDAVVRTVV---GLDRETTAAYMLILEAIDNGPVGKRHTGTAT 1087
Query: 201 LQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSST- 259
+ VTVLD +D P F Y A +P+D EG + + A D D G + Y
Sbjct: 1088 VFVTVLDVNDNRPIFLQSSYEASVPEDIPEGHSIL----QLKATDADEGEFGRVWYRILH 1143
Query: 260 GDHKQLIVVNKDTG-QVAATKQLIAELDPSVTIVLKATQVD-NPDRYALATLXXXXXXXX 317
G+H ++ G + + L E + S ++++A D P R ++ +
Sbjct: 1144 GNHGNNFRIHVSNGLLMRGPRPLDRERNSSHVLIVEAYNHDLGPMRSSVRVIVYVEDIND 1203
Query: 318 XXXXXXXXLQFTQKQYSTT-VSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDK 376
FTQ+QYS + E A G+ ++ + +++ + L Y K
Sbjct: 1204 EAPV------FTQQQYSRLGLRETAGIGTSVIVVQATDRDS--GDGGLVNYRILSGAEGK 1255
Query: 377 FAIN-NAGEVILRRSLDYETTSNYFYQVMVTDS---ISNDTASINISVEDVNEWEPRFRH 432
F I+ + G +I LDYET ++Y V TD + S+ I++ + + +F +
Sbjct: 1256 FEIDESTGLIITVNYLDYETKTSYMMNVSATDQAPPFNQGFCSVYITLLNELDEAVQFSN 1315
Query: 433 PQYE 436
YE
Sbjct: 1316 ASYE 1319
Score = 57.2 bits (132), Expect = 2e-07
Identities = 63/281 (22%), Positives = 123/281 (43%), Gaps = 20/281 (7%)
Query: 166 IIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTAL-L 224
+I V+ +D E + +T+ + V D G P + S + +TVLD +D +P+F + +A+ +
Sbjct: 1370 VITVQGLVDREKGDFYTLTV-VADDGGPKVDSTVKVYITVLDENDNSPRFDFTSDSAVSI 1428
Query: 225 PDDAEEGTFLTTSPGPISAADQDLGINAPLQYS-STGDHK---QLIVVNKDTGQVAATKQ 280
P+D G + T + A D D G N + +S ++G+ +++ N G+V +
Sbjct: 1429 PEDCPVGQRVAT----VKAWDPDAGSNGQVVFSLASGNIAGAFEIVTTNDSIGEVFVARP 1484
Query: 281 LIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEG 340
L E + + A+ P R L + Y+ +V+E
Sbjct: 1485 LDREELDHYILQVVASDRGTPPRKKDHILQVTILDINDNPPVIE----SPFGYNVSVNEN 1540
Query: 341 ASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAINN-AGEVILRRS-LDYETTSN 398
G+ ++ + ++ S L +Y+++ + F ++ +GE+ R + D E S
Sbjct: 1541 VGGGTAVVQVRATDRDIGI-NSVLSYYITEGNKDMTFRMDRISGEIATRPAPPDRERQSF 1599
Query: 399 YFYQVMVTDS---ISNDTASINISVEDVNEWEPRFRHPQYE 436
Y V D + T + +++ D N+ P F+ P YE
Sbjct: 1600 YHLVATVEDEGTPTLSATTHVYVTIVDENDNAPMFQQPHYE 1640
Score = 56.0 bits (129), Expect = 6e-07
Identities = 74/355 (20%), Positives = 144/355 (40%), Gaps = 30/355 (8%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
V + + + NDN P + Y + + E +D D G + Y P
Sbjct: 446 VKITLINENDNRPIFSQPLYNISLYENVTVGTSVLTVLATDNDA-GTFGEVSYFFSDDP- 503
Query: 154 SEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNP 213
+ + + I+++ + LD+E + FT+ + +D G + +++ VLD +D P
Sbjct: 504 -DRFSLDKDTGLIMLIAR-LDYELIQRFTLTIIARDGGGEE--TTGRVRINVLDVNDNVP 559
Query: 214 KFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQY-----SSTGDHKQLIVV 268
F + Y L ++ T L + A D+D N + Y S+ G + I +
Sbjct: 560 TFQKDAYVGALRENEPSVTQLVR----LRATDEDSPPNNQITYSIVSASAFGSYFD-ISL 614
Query: 269 NKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQF 328
+ G ++ ++ L E + I L +D + +T+ F
Sbjct: 615 YEGYGVISVSRPLDYEQISNGLIYLTVMAMDAGNPPLNSTVPVTIEVFDENDNPPT---F 671
Query: 329 TQKQYSTTVSEGASPGSVLLTL--TTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEV 385
++ Y +V E G+ +L L T + ++ E+ + + + + + +F IN +GE+
Sbjct: 672 SKPAYFVSVVENIMAGATVLFLNATDLDRSREYGQESIIYSLEGST---QFRINARSGEI 728
Query: 386 ILRRSLDYETTSNYFYQVMVTD-----SISNDTASINISVEDVNEWEPRFRHPQY 435
LD ET S Y V D + A++NI++ D+N+ P ++ Y
Sbjct: 729 TTTSLLDRETKSEYILIVRAVDGGVGHNQKTGIATVNITLLDINDNHPTWKDAPY 783
Score = 54.0 bits (124), Expect = 2e-06
Identities = 66/247 (26%), Positives = 110/247 (44%), Gaps = 29/247 (11%)
Query: 50 IVPGSKNLTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQW- 108
I P S + + LDRE + S + V D + + P+ V + D++DN P +
Sbjct: 2666 IDPISGLIQTAQRLDRESQAVYSLILV--ASDLGQPVPYETMQPLQVALEDIDDNEPLFV 2723
Query: 109 ---EGAPY--AVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENEL 163
+G+P + V E + GP++ ++Y + G +E F +
Sbjct: 2724 RPPKGSPQYQLLTVPEHSPRGTLVGNVTGAVDADEGPNAIVYYFIAAG--NEEKNFHLQP 2781
Query: 164 EPIIVVKKPLDFE--TVNNFTIKLRVQDQGSPP--------LYSDTTLQ---VTVLDADD 210
+ ++V + LD E + +F +K +PP L +D TLQ V + D +D
Sbjct: 2782 DGCLLVLRDLDREREAIFSFIVKASSNRSWTPPRGPSPTLDLVADLTLQEVRVVLEDIND 2841
Query: 211 QNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDH--KQLIVV 268
Q P+FT YTA + DA+ G+ L + A D D+G N+ + YS H + L
Sbjct: 2842 QPPRFTKAEYTAGVATDAKVGSELI----QVLALDADIGNNSLVFYSILAIHYFRALAND 2897
Query: 269 NKDTGQV 275
++D GQV
Sbjct: 2898 SEDVGQV 2904
Score = 50.0 bits (114), Expect = 4e-05
Identities = 55/227 (24%), Positives = 92/227 (40%), Gaps = 12/227 (5%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRA---LDREE 67
+ ED P G I L + G + R+ N L+R LDRE
Sbjct: 1111 VPEDIPEGHSILQLKATDADEGEFGRVWYRILHGNHGNNFRIHVSNGLLMRGPRPLDRER 1170
Query: 68 KIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYA-VRVSETXXXXXX 126
S+V + V + V V V D+ND AP + Y+ + + ET
Sbjct: 1171 N--SSHVLI-VEAYNHDLGPMRSSVRVIVYVEDINDEAPVFTQQQYSRLGLRETAGIGTS 1227
Query: 127 XXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFE-NELEPIIVVKKPLDFETVNNFTIKL 185
+DRD G ++Y +L G + FE +E +I+ LD+ET ++ + +
Sbjct: 1228 VIVVQATDRDS-GDGGLVNYRILSGAEGK---FEIDESTGLIITVNYLDYETKTSYMMNV 1283
Query: 186 RVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGT 232
DQ P ++ +T+L+ D+ +F+ Y A + ++ GT
Sbjct: 1284 SATDQAPPFNQGFCSVYITLLNELDEAVQFSNASYEAAILENLALGT 1330
Score = 44.8 bits (101), Expect = 0.001
Identities = 36/111 (32%), Positives = 50/111 (45%), Gaps = 7/111 (6%)
Query: 328 FTQKQYST--TVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGE 384
FT + T +SE GS + L + + PL F VS FA+ + G
Sbjct: 31 FTNHFFDTYLLISEDTPVGSSVTQLLAQDMDND----PLVFGVSGEEASRFFAVEPDTGV 86
Query: 385 VILRRSLDYETTSNYFYQVMVTDSISNDTASINISVEDVNEWEPRFRHPQY 435
V LR+ LD ET S + + V+D T +NI V DVN+ P F + Y
Sbjct: 87 VWLRQPLDRETKSEFTVEFSVSDHQGVITRKVNIQVGDVNDNAPTFHNQPY 137
>AL772287-2|CAI13626.1| 3359|Homo sapiens cadherin-like 23 protein.
Length = 3359
Score = 99.5 bits (237), Expect = 5e-20
Identities = 96/369 (26%), Positives = 156/369 (42%), Gaps = 28/369 (7%)
Query: 80 CDRRRTTDP-SFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQP 138
C R R P S + V +RV D+NDN P P + +SE SD D
Sbjct: 1827 CARDRGMPPLSSTMLVGIRVLDINDNDPVLLNLPMNITISENSPVSSFVAHVLASDADS- 1885
Query: 139 GPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYS- 197
G ++ L + + G + E F N I+ V +PLD E + + + + V+D P +
Sbjct: 1886 GCNARLTFNITAG-NRERAFFINATTGIVTVNRPLDRERIPEYKLTISVKDNPENPRIAR 1944
Query: 198 -DTTLQVTVL-DADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQ 255
D L + L D +D +P FT Y A + +++ GT LT GPI A D D I A +
Sbjct: 1945 RDYDLLLIFLSDENDNHPLFTKSTYQAEVMENSPAGTPLTVLNGPILALDADQDIYAVVT 2004
Query: 256 YSSTGDHKQLIVVNKDTGQVAATKQLIAELD----PSVTIVLKATQVD--NPDRYALATL 309
Y G L +N TG V +I + + P + ++L A + N + L T+
Sbjct: 2005 YQLLGAQSGLFDINSSTGVVTVRSGVIIDREAFSPPILELLLLAEDIGLLNSTAHLLITI 2064
Query: 310 XXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVS 369
F+ + + E PG +L +T +++ + Y
Sbjct: 2065 LDDNDNRPT---------FSPATLTVHLLENCPPGFSVLQVTATDEDSGLNGELV--YRI 2113
Query: 370 DRSFLDKFAINNAGEVIL--RRSLDYETTSNYFYQVMVTDSIS---NDTASINISVEDVN 424
+ D+F I+ VI ++D E +Y V+ TD + + TA + I ++D+N
Sbjct: 2114 EAGAQDRFLIHLVTGVIRVGNATIDREEQESYRLTVVATDRGTVPLSGTAIVTILIDDIN 2173
Query: 425 EWEPRFRHP 433
+ P F +P
Sbjct: 2174 DSRPEFLNP 2182
Score = 94.3 bits (224), Expect = 2e-18
Identities = 102/417 (24%), Positives = 179/417 (42%), Gaps = 26/417 (6%)
Query: 28 GDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEKIGPSNVYVNVRCDRRRTTD 87
G ++D D + QE AV I GS ++++ E + V ++V + +
Sbjct: 2218 GIVAKDDTDRLVPNQEDAFAVNINTGS---VMVKSPMNRELVATYEVTLSVIDNASDLPE 2274
Query: 88 PSFVIP---VSVRVWDVNDNAPQWE--GAPYAV-RVSETXXXXXXXXXXXXSDRDQPGPH 141
S +P ++V V DVNDN PQ++ G Y + R+ E D D+ G +
Sbjct: 2275 RSVSVPNAKLTVNVLDVNDNTPQFKPFGITYYMERILEGATPGTTLIAVAAVDPDK-GLN 2333
Query: 142 SALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTL 201
+ Y +L Y+ E+ ++ + +D+E V+ +R D GSPP ++ +
Sbjct: 2334 GLVTYTLLDLVPPGYVQLEDSSAGKVIANRTVDYEEVHWLNFTVRASDNGSPPRAAEIPV 2393
Query: 202 QVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGD 261
+ ++D +D NP F Y + +D GT + T ++A D D G A ++Y S GD
Sbjct: 2394 YLEIVDINDNNPIFDQPSYQEAVFEDVPVGTIILT----VTATDADSGNFALIEY-SLGD 2448
Query: 262 HKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNP-DRYALATLXXXXXXXXXXX 320
+ +N TG + L + + +L A DNP D +
Sbjct: 2449 GESKFAINPTTGDIYVLSSL--DREKKDHYILTALAKDNPGDVASNRRENSVQVVIQVLD 2506
Query: 321 XXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAIN 380
QF++ Q+ST+V E G+ ++T+ Q+ E L Y + ++ F ++
Sbjct: 2507 VNDCRPQFSKPQFSTSVYENEPAGTSVITMMATDQD-EGPNGELT-YSLEGPGVEAFHVD 2564
Query: 381 -NAGEVILRRSLDYETTSNYFYQVMVTDSISN---DTASINISVEDVNEWEPRFRHP 433
++G V +R L ++ + V+ TD T + + V DVN+ P F P
Sbjct: 2565 MDSGLVTTQRPL--QSYEKFSLTVVATDGGEPPLWGTTMLLVEVIDVNDNRPVFVRP 2619
Score = 92.7 bits (220), Expect = 5e-18
Identities = 101/454 (22%), Positives = 197/454 (43%), Gaps = 42/454 (9%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEK-- 68
+ ED P+G+II T++ S + I L + + I P + ++ +L +LDRE+K
Sbjct: 2416 VFEDVPVGTIILTVTATDADSGNFALIEYSLGDGESKFAINPTTGDIYVLSSLDREKKDH 2475
Query: 69 -----IGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXX 123
+ N +V +RR + + V ++V DVND PQ+ ++ V E
Sbjct: 2476 YILTALAKDNP-GDVASNRRENS-----VQVVIQVLDVNDCRPQFSKPQFSTSVYENEPA 2529
Query: 124 XXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTI 183
+D+D+ GP+ L Y+ L GP E + + ++ ++PL ++ F++
Sbjct: 2530 GTSVITMMATDQDE-GPNGELTYS-LEGPGVEAFHVDMD-SGLVTTQRPL--QSYEKFSL 2584
Query: 184 KLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISA 243
+ D G PPL+ T L V V+D +D P F +L E L ++ + A
Sbjct: 2585 TVVATDGGEPPLWGTTMLLVEVIDVNDNRPVFVRPPNGTIL--HIREEIPLRSNVYEVYA 2642
Query: 244 ADQDLGINAPLQYS--STGDHK--QLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVD 299
D+D G+N ++YS T ++ + +++ +G + ++L E +++L A+ +
Sbjct: 2643 TDKDEGLNGAVRYSFLKTAGNRDWEFFIIDPISGLIQTAQRLDRESQAVYSLILVASDLG 2702
Query: 300 NPDRY-ALATLXXXXXXXXXXXXXXXXLQFTQKQYS-TTVSEGASPGSVLLTLTTVPQNT 357
P Y + L QY TV E + G+++ +T
Sbjct: 2703 QPVPYETMQPLQVALEDIDDNEPLFVRPPKGSPQYQLLTVPEHSPRGTLVGNVTGAVDAD 2762
Query: 358 EFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVT----------- 406
E + + ++++ + F + G +++ R LD E + + + V +
Sbjct: 2763 EGPNAIVYYFIAAGNEEKNFHLQPDGCLLVLRDLDREREAIFSFIVKASSNRSWTPPRGP 2822
Query: 407 ----DSISNDT-ASINISVEDVNEWEPRFRHPQY 435
D +++ T + + +ED+N+ PRF +Y
Sbjct: 2823 SPTLDLVADLTLQEVRVVLEDINDQPPRFTKAEY 2856
Score = 92.3 bits (219), Expect = 7e-18
Identities = 102/442 (23%), Positives = 174/442 (39%), Gaps = 30/442 (6%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEKIG 70
ISEDTP+GS + L D D + +E + P + + L + LDRE K
Sbjct: 42 ISEDTPVGSSVTQLLAQ-DMDNDPLVFGVSGEEASRFFAVEPDTGVVWLRQPLDRETK-- 98
Query: 71 PSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXX 130
S V + V+++V DVNDNAP + PY+VR+ E
Sbjct: 99 -SEFTVEFSVSDHQGV---ITRKVNIQVGDVNDNAPTFHNQPYSVRIPEVGATGNTPVGT 154
Query: 131 XXSDRDQPGPHSALHYAVLPG--PHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQ 188
+ P +VL P S++ ++ I+ V + LD+ET + + +
Sbjct: 155 PIFIVNATDPDLGAGGSVLYSFQPPSQFFAIDS-ARGIVTVIRELDYETTQAYQLTVNAT 213
Query: 189 DQG-SPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQD 247
DQ + PL + L + + D D +P F Y+ + + + GT + I+A DQD
Sbjct: 214 DQDKTRPLSTLANLAIIITDVQDMDPIFINLPYSTNIYEHSPPGTTVRI----ITAIDQD 269
Query: 248 LGINAPLQY---SSTGDHKQLIVVNKDTGQVAATKQLIAE---LDPSVTIVLKATQVDNP 301
G + Y S G+ + ++ +G + L E + +K T++ N
Sbjct: 270 KGRPRGIGYTIVSVAGNTNSIFALDYISGVLTLNGLLDRENPLYSHGFILTVKGTEL-ND 328
Query: 302 DRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRE 361
DR +F +YS ++E A G L V E
Sbjct: 329 DRTPSDATVTTTFNILVIDINDNAPEFNSSEYSVAITELAQVGFALPLFIQVVDKDEGLN 388
Query: 362 SPLQFYV----SDRSFLDKFAINNAGEVILRRS--LDYETTSNYFYQVMVTDSISNDT-- 413
S + Y+ S + ++ ++ +R + LDYET Y + + +S+ +
Sbjct: 389 SMFEVYLVGNNSHHFIISPTSVQGKADIRIRVAIPLDYETVDRYDFDLFANESVPDHVGY 448
Query: 414 ASINISVEDVNEWEPRFRHPQY 435
A + I++ + N+ P F P Y
Sbjct: 449 AKVKITLINENDNRPIFSQPLY 470
Score = 84.2 bits (199), Expect = 2e-15
Identities = 105/449 (23%), Positives = 173/449 (38%), Gaps = 31/449 (6%)
Query: 91 VIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLP 150
+ V++ + D+NDN P W+ APY + + E D D G + L Y++ P
Sbjct: 766 IATVNITLLDINDNHPTWKDAPYYINLVEMTPPDSDVTTVVAVDPDL-GENGTLVYSIQP 824
Query: 151 GPHSEY-----LGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPL--YSDTTLQV 203
P+ Y G ++ + P E I + V D G PPL S T+ V
Sbjct: 825 -PNKFYSLNSTTGKIRTTHAMLDRENPDPHEAELMRKIVVSVTDCGRPPLKATSSATVFV 883
Query: 204 TVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQY-SSTGDH 262
+LD +D +P F + A + EG S + A D D G+N + Y G
Sbjct: 884 NLLDLNDNDPTFQNLPFVA----EVLEGIPAGVSIYQVVAIDLDEGLNGLVSYRMPVGMP 939
Query: 263 KQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXX 322
+ ++N +G V T +L E + + A+ P + + +TL
Sbjct: 940 RMDFLINSSSGVVVTTTELDRERIAEYQLRVVASDAGTPTKSSTSTLTIHVLDVNDETPT 999
Query: 323 XXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAINNA 382
F Y+ +VSE P + N + L ++++ + KF++
Sbjct: 1000 -----FFPAVYNVSVSEDV-PREFRVVWLNCTDNDVGLNAELSYFITGGNVDGKFSVGYR 1053
Query: 383 GEVILR-RSLDYETTSNYFYQVMVTDS-----ISNDTASINISVEDVNEWEPRFRHPQYE 436
V+ LD ETT+ Y + D+ TA++ ++V DVN+ P F YE
Sbjct: 1054 DAVVRTVVGLDRETTAAYMLILEAIDNGPVGKRHTGTATVFVTVLDVNDNRPIFLQSSYE 1113
Query: 437 FEXXXXXXXXXXXXXXXXXXXXVAHDGDAGTLALS-LAGQHARMFYINASGDLFLR-EEA 494
A +G+ G + L G H F I+ S L +R
Sbjct: 1114 ---ASVPEDIPEGHSILQLKATDADEGEFGRVWYRILHGNHGNNFRIHVSNGLLMRGPRP 1170
Query: 495 IGNLNSSSLHLVATAIDSGIPPRQTSVPV 523
+ +SS L+ A + + P ++SV V
Sbjct: 1171 LDRERNSSHVLIVEAYNHDLGPMRSSVRV 1199
Score = 81.0 bits (191), Expect = 2e-14
Identities = 113/480 (23%), Positives = 186/480 (38%), Gaps = 47/480 (9%)
Query: 63 LDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXX 122
+DREE+ + + V R T S V++ + D+ND+ P++ V V E+
Sbjct: 2137 IDREEQ---ESYRLTVVATDRGTVPLSGTAIVTILIDDINDSRPEFLNPIQTVSVLESAE 2193
Query: 123 XXXXXXXXXXSDRDQPGPHSALHYAVLPG--------PHSEYLGFENELEPIIVVKKPLD 174
D D P H + P+ E N ++VK P++
Sbjct: 2194 PGTVIANITAIDHDL-NPKLEYHIVGIVAKDDTDRLVPNQEDAFAVNINTGSVMVKSPMN 2252
Query: 175 FETVNNFTIKLRVQDQGSP-PLYS----DTTLQVTVLDADDQNPKFT---YEHYTALLPD 226
E V + + L V D S P S + L V VLD +D P+F +Y + +
Sbjct: 2253 RELVATYEVTLSVIDNASDLPERSVSVPNAKLTVNVLDVNDNTPQFKPFGITYYMERILE 2312
Query: 227 DAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDT--GQVAATKQLIAE 284
A GT L ++A D D G+N + Y+ V +D+ G+V A + + E
Sbjct: 2313 GATPGTTLIA----VAAVDPDKGLNGLVTYTLLDLVPPGYVQLEDSSAGKVIANRTVDYE 2368
Query: 285 LDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPG 344
+ ++A+ +P R A + F Q Y V E G
Sbjct: 2369 EVHWLNFTVRASDNGSPPRAAEIPVYLEIVDINDNNPI-----FDQPSYQEAVFEDVPVG 2423
Query: 345 SVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQV 403
+++LT+T ++ + +++ + D KFAIN G++ + SLD E +Y
Sbjct: 2424 TIILTVTATDADSG-NFALIEYSLGDGE--SKFAINPTTGDIYVLSSLDREKKDHYILTA 2480
Query: 404 MVTDS----ISN---DTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXX 456
+ D+ SN ++ + I V DVN+ P+F PQ+
Sbjct: 2481 LAKDNPGDVASNRRENSVQVVIQVLDVNDCRPQFSKPQFSTSVYENEPAGTSVITMMATD 2540
Query: 457 XXVAHDGDAGTLALSLAGQHARMFYINASGDLFLREEAIGNLNSSSLHLVATAIDSGIPP 516
+G G L SL G F+++ L + + + SL +VAT D G PP
Sbjct: 2541 QD---EGPNGELTYSLEGPGVEAFHVDMDSGLVTTQRPLQSYEKFSLTVVAT--DGGEPP 2595
Score = 80.6 bits (190), Expect = 2e-14
Identities = 106/480 (22%), Positives = 181/480 (37%), Gaps = 35/480 (7%)
Query: 57 LTLLRALDREEKIGPSNVYVNVRC----DRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAP 112
LTL LDRE + + V+ D R +D + ++ V D+NDNAP++ +
Sbjct: 300 LTLNGLLDRENPLYSHGFILTVKGTELNDDRTPSDATVTTTFNILVIDINDNAPEFNSSE 359
Query: 113 YAVRVSETXXXXXXX-XXXXXSDRDQPGPHSALHYAVLPGPHSEYL-----GFENELEPI 166
Y+V ++E D+D+ G +S L G +S + + + +
Sbjct: 360 YSVAITELAQVGFALPLFIQVVDKDE-GLNSMFE-VYLVGNNSHHFIISPTSVQGKADIR 417
Query: 167 IVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPD 226
I V PLD+ETV+ + L ++ P +++T+++ +D P F+ Y L +
Sbjct: 418 IRVAIPLDYETVDRYDFDL-FANESVPDHVGYAKVKITLINENDNRPIFSQPLYNISLYE 476
Query: 227 DAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLIAELD 286
+ GT + T + A D D G + Y + D + + +KDTG + +L EL
Sbjct: 477 NVTVGTSVLT----VLATDNDAGTFGEVSYFFSDDPDRFSL-DKDTGLIMLIARLDYELI 531
Query: 287 PSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSV 346
T+ + A + + F + Y + E +
Sbjct: 532 QRFTLTIIARDGGGEETTGRVRINVLDVNDNVPT-------FQKDAYVGALRENEPSVTQ 584
Query: 347 LLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAIN---NAGEVILRRSLDYETTSN--YFY 401
L+ L +++ VS +F F I+ G + + R LDYE SN +
Sbjct: 585 LVRLRATDEDSPPNNQITYSIVSASAFGSYFDISLYEGYGVISVSRPLDYEQISNGLIYL 644
Query: 402 QVMVTDSIS---NDTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXX 458
VM D+ + N T + I V D N+ P F P Y
Sbjct: 645 TVMAMDAGNPPLNSTVPVTIEVFDENDNPPTFSKPAYFVSVVENIMAGATVLFLNATDLD 704
Query: 459 VAHDGDAGTLALSLAGQHARMFYINASGDLFLREEAIGNLNSSSLHLVATAIDSGIPPRQ 518
+ + ++ SL G + F INA + S L+ A+D G+ Q
Sbjct: 705 RSREYGQESIIYSLEG--STQFRINARSGEITTTSLLDRETKSEYILIVRAVDGGVGHNQ 762
Score = 78.6 bits (185), Expect = 9e-14
Identities = 88/354 (24%), Positives = 153/354 (43%), Gaps = 31/354 (8%)
Query: 94 VSVRVWDVNDNAP----QWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVL 149
V V V D+NDN P +EG P+ V + DRD GP+ + Y+++
Sbjct: 1735 VLVNVNDINDNVPTFPRDYEG-PFEVTEGQPGPRVWTFLAH---DRDS-GPNGQVEYSIM 1789
Query: 150 PG-PHSEYLGFENELEPIIVVKKP--LDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVL 206
G P E++ + +E ++ V+K LD ET+ + + + +D+G PPL S + + VL
Sbjct: 1790 DGDPLGEFV--ISPVEGVLRVRKDVELDRETIAFYNLTICARDRGMPPLSSTMLVGIRVL 1847
Query: 207 DADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSST-GDHKQL 265
D +D +P + +++ +F+ + A+D D G NA L ++ T G+ ++
Sbjct: 1848 DINDNDPVLLNLPMNITISENSPVSSFV----AHVLASDADSGCNARLTFNITAGNRERA 1903
Query: 266 IVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXX 325
+N TG V + L E P + + DNP+ +A
Sbjct: 1904 FFINATTGIVTVNRPLDRERIPEYKLTISVK--DNPENPRIARRDYDLLLIFLSDENDNH 1961
Query: 326 LQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDR---SFLDKFAINNA 382
FT+ Y V E SP LT+ P + + V+ + + F IN++
Sbjct: 1962 PLFTKSTYQAEVMEN-SPAGTPLTVLNGPILALDADQDIYAVVTYQLLGAQSGLFDINSS 2020
Query: 383 GEVILRRS---LDYETTSNYFYQVMVTD---SISNDTASINISVEDVNEWEPRF 430
V+ RS +D E S ++++ + N TA + I++ D N+ P F
Sbjct: 2021 TGVVTVRSGVIIDREAFSPPILELLLLAEDIGLLNSTAHLLITILDDNDNRPTF 2074
Score = 77.0 bits (181), Expect = 3e-13
Identities = 81/352 (23%), Positives = 144/352 (40%), Gaps = 24/352 (6%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPG-P 152
V V + D+NDN P ++ P+ V E D D+ G + + Y + G P
Sbjct: 881 VFVNLLDLNDNDPTFQNLPFVAEVLEGIPAGVSIYQVVAIDLDE-GLNGLVSYRMPVGMP 939
Query: 153 HSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQN 212
++L N ++V LD E + + +++ D G+P S +TL + VLD +D+
Sbjct: 940 RMDFL--INSSSGVVVTTTELDRERIAEYQLRVVASDAGTPTKSSTSTLTIHVLDVNDET 997
Query: 213 PKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQ-LIVVNKD 271
P F Y + +D + ++ D D+G+NA L Y TG + V
Sbjct: 998 PTFFPAVYNVSVSEDVPREFRVVW----LNCTDNDVGLNAELSYFITGGNVDGKFSVGYR 1053
Query: 272 TGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQK 331
V L E + ++L+A +DN T + F Q
Sbjct: 1054 DAVVRTVVGLDRETTAAYMLILEA--IDNGPVGKRHTGTATVFVTVLDVNDNRPI-FLQS 1110
Query: 332 QYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILR--R 389
Y +V E G +L L + E + + + + + F I+ + +++R R
Sbjct: 1111 SYEASVPEDIPEGHSILQLKATDAD-EGEFGRVWYRILHGNHGNNFRIHVSNGLLMRGPR 1169
Query: 390 SLDYETTSNYFYQVMVTDSISND------TASINISVEDVNEWEPRFRHPQY 435
LD E S++ V++ ++ ++D + + + VED+N+ P F QY
Sbjct: 1170 PLDRERNSSH---VLIVEAYNHDLGPMRSSVRVIVYVEDINDEAPVFTQQQY 1218
Score = 74.1 bits (174), Expect = 2e-12
Identities = 83/355 (23%), Positives = 153/355 (43%), Gaps = 28/355 (7%)
Query: 92 IPVSVRVWDVNDNAPQWE-GAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLP 150
+ V + V D NDN+P+++ + AV + E D D G + + +++
Sbjct: 1407 VKVYITVLDENDNSPRFDFTSDSAVSIPEDCPVGQRVATVKAWDPDA-GSNGQVVFSLAS 1465
Query: 151 GPHSEYLGFENELEPI--IVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDA 208
G + + I + V +PLD E ++++ +++ D+G+PP D LQVT+LD
Sbjct: 1466 GNIAGAFEIVTTNDSIGEVFVARPLDREELDHYILQVVASDRGTPPRKKDHILQVTILDI 1525
Query: 209 DDQNPKFTYEH-YTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIV 267
+D P Y + ++ GT + + A D+D+GIN+ L Y T +K +
Sbjct: 1526 NDNPPVIESPFGYNVSVNENVGGGTAVV----QVRATDRDIGINSVLSYYITEGNKDMAF 1581
Query: 268 -VNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXL 326
+++ +G++ AT+ + + L AT D AT
Sbjct: 1582 RMDRISGEI-ATRPAPPDRERQSFYHLVATVEDEGTPTLSAT---THVYVTIVDENDNAP 1637
Query: 327 QFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESP---LQFYVSDRSFLDKFAIN-NA 382
F Q Y + EG P ++ +L T+ Q + E P + + + + ++ F I+ +
Sbjct: 1638 MFQQPHYEVLLDEG--PDTLNTSLITI-QALDLDEGPNGTVTYAIVAGNIVNTFRIDRHM 1694
Query: 383 GEVILRRSLDYETT-SNYFYQVMVTDSIS------NDTASINISVEDVNEWEPRF 430
G + + LDYE + Y V TD T ++ ++V D+N+ P F
Sbjct: 1695 GVITAAKELDYEISHGRYTLIVTATDQCPILSHRLTSTTTVLVNVNDINDNVPTF 1749
Score = 70.1 bits (164), Expect = 3e-11
Identities = 82/363 (22%), Positives = 148/363 (40%), Gaps = 33/363 (9%)
Query: 96 VRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSE 155
+ + D NDN P + A V + E +D D G + L Y + G
Sbjct: 2062 ITILDDNDNRPTFSPATLTVHLLENCPPGFSVLQVTATDEDS-GLNGELVYRIEAGAQDR 2120
Query: 156 YLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKF 215
+L I V +D E ++ + + D+G+ PL + + + D +D P+F
Sbjct: 2121 FL-IHLVTGVIRVGNATIDREEQESYRLTVVATDRGTVPLSGTAIVTILIDDINDSRPEF 2179
Query: 216 TYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTG-----DHKQLI---- 266
T + + AE GT + I+A D DL N L+Y G D +L+
Sbjct: 2180 LNPIQTVSVLESAEPGTVIAN----ITAIDHDL--NPKLEYHIVGIVAKDDTDRLVPNQE 2233
Query: 267 ---VVNKDTGQVAA----TKQLIAELDPSVTIVLKATQVDNPDR-YALATLXXXXXXXXX 318
VN +TG V ++L+A + +++++ A+ D P+R ++
Sbjct: 2234 DAFAVNINTGSVMVKSPMNRELVATYEVTLSVIDNAS--DLPERSVSVPNAKLTVNVLDV 2291
Query: 319 XXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSD--RSFLDK 376
F Y + EGA+PG+ L+ + V + + + + D +
Sbjct: 2292 NDNTPQFKPFGITYYMERILEGATPGTTLIAVAAVDPDKGL-NGLVTYTLLDLVPPGYVQ 2350
Query: 377 FAINNAGEVILRRSLDYETTSNYFYQVMVTDSISNDTAS---INISVEDVNEWEPRFRHP 433
++AG+VI R++DYE + V +D+ S A+ + + + D+N+ P F P
Sbjct: 2351 LEDSSAGKVIANRTVDYEEVHWLNFTVRASDNGSPPRAAEIPVYLEIVDINDNNPIFDQP 2410
Query: 434 QYE 436
Y+
Sbjct: 2411 SYQ 2413
Score = 66.5 bits (155), Expect = 4e-10
Identities = 83/392 (21%), Positives = 146/392 (37%), Gaps = 17/392 (4%)
Query: 48 VGIVPGSKNLTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQ 107
+ + G +++ R LD E+ I +Y+ V + +PV++ V+D NDN P
Sbjct: 617 ISLYEGYGVISVSRPLDYEQ-ISNGLIYLTVMAMDAGNPPLNSTVPVTIEVFDENDNPPT 675
Query: 108 WEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPII 167
+ Y V V E +D D+ + +++ N I
Sbjct: 676 FSKPAYFVSVVENIMAGATVLFLNATDLDRSREYG--QESIIYSLEGSTQFRINARSGEI 733
Query: 168 VVKKPLDFETVNNFTIKLRVQD--QGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLP 225
LD ET + + + +R D G T+ +T+LD +D +P + Y L
Sbjct: 734 TTTSLLDRETKSEYILIVRAVDGGVGHNQKTGIATVNITLLDINDNHPTWKDAPYYINLV 793
Query: 226 DDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLI--A 283
+ + +TT + A D DLG N L YS +K +N TG++ T ++
Sbjct: 794 EMTPPDSDVTT----VVAVDPDLGENGTLVYSIQPPNK-FYSLNSTTGKIRTTHAMLDRE 848
Query: 284 ELDPSVTIVLKATQVDNPD--RYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGA 341
DP +++ V D R L F + V EG
Sbjct: 849 NPDPHEAELMRKIVVSVTDCGRPPLKATSSATVFVNLLDLNDNDPTFQNLPFVAEVLEGI 908
Query: 342 SPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFY 401
G + + + + +D +++G V+ LD E + Y
Sbjct: 909 PAGVSIYQVVAIDLDEGLNGLVSYRMPVGMPRMDFLINSSSGVVVTTTELDRERIAEYQL 968
Query: 402 QVMVTDS---ISNDTASINISVEDVNEWEPRF 430
+V+ +D+ + T+++ I V DVN+ P F
Sbjct: 969 RVVASDAGTPTKSSTSTLTIHVLDVNDETPTF 1000
Score = 64.1 bits (149), Expect = 2e-09
Identities = 53/222 (23%), Positives = 94/222 (42%), Gaps = 10/222 (4%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVL-PGP 152
V + V DVNDN P ++ Y + E +D D P P++ + Y+++
Sbjct: 552 VRINVLDVNDNVPTFQKDAYVGALRENEPSVTQLVRLRATDEDSP-PNNQITYSIVSASA 610
Query: 153 HSEYLGFE-NELEPIIVVKKPLDFETVNNFTIKLRV--QDQGSPPLYSDTTLQVTVLDAD 209
Y E +I V +PLD+E ++N I L V D G+PPL S + + V D +
Sbjct: 611 FGSYFDISLYEGYGVISVSRPLDYEQISNGLIYLTVMAMDAGNPPLNSTVPVTIEVFDEN 670
Query: 210 DQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVN 269
D P F+ Y + ++ G + ++ G + YS G + +N
Sbjct: 671 DNPPTFSKPAYFVSVVENIMAGATVLFLNATDLDRSREYG-QESIIYSLEGSTQ--FRIN 727
Query: 270 KDTGQVAATKQLIAELDPSVTIVLKATQ--VDNPDRYALATL 309
+G++ T L E ++++A V + + +AT+
Sbjct: 728 ARSGEITTTSLLDRETKSEYILIVRAVDGGVGHNQKTGIATV 769
Score = 62.1 bits (144), Expect = 9e-09
Identities = 90/364 (24%), Positives = 150/364 (41%), Gaps = 28/364 (7%)
Query: 85 TTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSAL 144
T S +++ V DVND P + A Y V VSE +D D G ++ L
Sbjct: 977 TPTKSSTSTLTIHVLDVNDETPTFFPAVYNVSVSEDVPREFRVVWLNCTDND-VGLNAEL 1035
Query: 145 HYAVLPG--PHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGS-PPLYSDT-T 200
Y + G +G+ + + +V LD ET + + L D G ++ T T
Sbjct: 1036 SYFITGGNVDGKFSVGYRDAVVRTVV---GLDRETTAAYMLILEAIDNGPVGKRHTGTAT 1092
Query: 201 LQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSST- 259
+ VTVLD +D P F Y A +P+D EG + + A D D G + Y
Sbjct: 1093 VFVTVLDVNDNRPIFLQSSYEASVPEDIPEGHSIL----QLKATDADEGEFGRVWYRILH 1148
Query: 260 GDHKQLIVVNKDTG-QVAATKQLIAELDPSVTIVLKATQVD-NPDRYALATLXXXXXXXX 317
G+H ++ G + + L E + S ++++A D P R ++ +
Sbjct: 1149 GNHGNNFRIHVSNGLLMRGPRPLDRERNSSHVLIVEAYNHDLGPMRSSVRVIVYVEDIND 1208
Query: 318 XXXXXXXXLQFTQKQYSTT-VSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDK 376
FTQ+QYS + E A G+ ++ + +++ + L Y K
Sbjct: 1209 EAPV------FTQQQYSRLGLRETAGIGTSVIVVQATDRDS--GDGGLVNYRILSGAEGK 1260
Query: 377 FAIN-NAGEVILRRSLDYETTSNYFYQVMVTDS---ISNDTASINISVEDVNEWEPRFRH 432
F I+ + G +I LDYET ++Y V TD + S+ I++ + + +F +
Sbjct: 1261 FEIDESTGLIITVNYLDYETKTSYMMNVSATDQAPPFNQGFCSVYITLLNELDEAVQFSN 1320
Query: 433 PQYE 436
YE
Sbjct: 1321 ASYE 1324
Score = 57.2 bits (132), Expect = 2e-07
Identities = 59/281 (20%), Positives = 123/281 (43%), Gaps = 20/281 (7%)
Query: 166 IIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTAL-L 224
+I V+ +D E + +T+ + V D G P + S + +TVLD +D +P+F + +A+ +
Sbjct: 1375 VITVQGLVDREKGDFYTLTV-VADDGGPKVDSTVKVYITVLDENDNSPRFDFTSDSAVSI 1433
Query: 225 PDDAEEGTFLTTSPGPISAADQDLGINAPLQYS-STGDHK---QLIVVNKDTGQVAATKQ 280
P+D G + T + A D D G N + +S ++G+ +++ N G+V +
Sbjct: 1434 PEDCPVGQRVAT----VKAWDPDAGSNGQVVFSLASGNIAGAFEIVTTNDSIGEVFVARP 1489
Query: 281 LIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEG 340
L E + + A+ P R L + Y+ +V+E
Sbjct: 1490 LDREELDHYILQVVASDRGTPPRKKDHILQVTILDINDNPPVIE----SPFGYNVSVNEN 1545
Query: 341 ASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAINN-AGEVILRRSLDYETTSNY 399
G+ ++ + ++ S L +Y+++ + F ++ +GE+ R + ++
Sbjct: 1546 VGGGTAVVQVRATDRDIGIN-SVLSYYITEGNKDMAFRMDRISGEIATRPAPPDRERQSF 1604
Query: 400 FYQVMVTDSISNDTAS----INISVEDVNEWEPRFRHPQYE 436
++ V + T S + +++ D N+ P F+ P YE
Sbjct: 1605 YHLVATVEDEGTPTLSATTHVYVTIVDENDNAPMFQQPHYE 1645
Score = 56.0 bits (129), Expect = 6e-07
Identities = 74/355 (20%), Positives = 144/355 (40%), Gaps = 30/355 (8%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
V + + + NDN P + Y + + E +D D G + Y P
Sbjct: 451 VKITLINENDNRPIFSQPLYNISLYENVTVGTSVLTVLATDNDA-GTFGEVSYFFSDDP- 508
Query: 154 SEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNP 213
+ + + I+++ + LD+E + FT+ + +D G + +++ VLD +D P
Sbjct: 509 -DRFSLDKDTGLIMLIAR-LDYELIQRFTLTIIARDGGGEE--TTGRVRINVLDVNDNVP 564
Query: 214 KFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQY-----SSTGDHKQLIVV 268
F + Y L ++ T L + A D+D N + Y S+ G + I +
Sbjct: 565 TFQKDAYVGALRENEPSVTQLVR----LRATDEDSPPNNQITYSIVSASAFGSYFD-ISL 619
Query: 269 NKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQF 328
+ G ++ ++ L E + I L +D + +T+ F
Sbjct: 620 YEGYGVISVSRPLDYEQISNGLIYLTVMAMDAGNPPLNSTVPVTIEVFDENDNPPT---F 676
Query: 329 TQKQYSTTVSEGASPGSVLLTL--TTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEV 385
++ Y +V E G+ +L L T + ++ E+ + + + + + +F IN +GE+
Sbjct: 677 SKPAYFVSVVENIMAGATVLFLNATDLDRSREYGQESIIYSLEGST---QFRINARSGEI 733
Query: 386 ILRRSLDYETTSNYFYQVMVTD-----SISNDTASINISVEDVNEWEPRFRHPQY 435
LD ET S Y V D + A++NI++ D+N+ P ++ Y
Sbjct: 734 TTTSLLDRETKSEYILIVRAVDGGVGHNQKTGIATVNITLLDINDNHPTWKDAPY 788
Score = 54.0 bits (124), Expect = 2e-06
Identities = 66/247 (26%), Positives = 110/247 (44%), Gaps = 29/247 (11%)
Query: 50 IVPGSKNLTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQW- 108
I P S + + LDRE + S + V D + + P+ V + D++DN P +
Sbjct: 2671 IDPISGLIQTAQRLDRESQAVYSLILV--ASDLGQPVPYETMQPLQVALEDIDDNEPLFV 2728
Query: 109 ---EGAPY--AVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENEL 163
+G+P + V E + GP++ ++Y + G +E F +
Sbjct: 2729 RPPKGSPQYQLLTVPEHSPRGTLVGNVTGAVDADEGPNAIVYYFIAAG--NEEKNFHLQP 2786
Query: 164 EPIIVVKKPLDFE--TVNNFTIKLRVQDQGSPP--------LYSDTTLQ---VTVLDADD 210
+ ++V + LD E + +F +K +PP L +D TLQ V + D +D
Sbjct: 2787 DGCLLVLRDLDREREAIFSFIVKASSNRSWTPPRGPSPTLDLVADLTLQEVRVVLEDIND 2846
Query: 211 QNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDH--KQLIVV 268
Q P+FT YTA + DA+ G+ L + A D D+G N+ + YS H + L
Sbjct: 2847 QPPRFTKAEYTAGVATDAKVGSELI----QVLALDADIGNNSLVFYSILAIHYFRALAND 2902
Query: 269 NKDTGQV 275
++D GQV
Sbjct: 2903 SEDVGQV 2909
Score = 51.2 bits (117), Expect = 2e-05
Identities = 111/522 (21%), Positives = 189/522 (36%), Gaps = 37/522 (7%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRA---LDREE 67
+ ED P G I L + G + R+ N L+R LDRE
Sbjct: 1116 VPEDIPEGHSILQLKATDADEGEFGRVWYRILHGNHGNNFRIHVSNGLLMRGPRPLDRER 1175
Query: 68 KIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYA-VRVSETXXXXXX 126
S+V + V + V V V D+ND AP + Y+ + + ET
Sbjct: 1176 N--SSHVLI-VEAYNHDLGPMRSSVRVIVYVEDINDEAPVFTQQQYSRLGLRETAGIGTS 1232
Query: 127 XXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFE-NELEPIIVVKKPLDFETVNNFTIKL 185
+DRD G ++Y +L G + FE +E +I+ LD+ET ++ + +
Sbjct: 1233 VIVVQATDRDS-GDGGLVNYRILSGAEGK---FEIDESTGLIITVNYLDYETKTSYMMNV 1288
Query: 186 RVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGT-FLTTSPGPISAA 244
DQ P ++ +T+L+ D+ +F+ Y A + ++ GT + I
Sbjct: 1289 SATDQAPPFNQGFCSVYITLLNELDEAVQFSNASYEAAILENLALGTEIVRVQAYSIDNL 1348
Query: 245 DQ-DLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDR 303
+Q NA Y+ST K L ++ TG + T Q + + + L D +
Sbjct: 1349 NQITYRFNA---YTST-QAKALFKIDAITGVI--TVQGLVDREKGDFYTLTVVADDGGPK 1402
Query: 304 YALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESP 363
+ + FT + ++ E G + T+ +
Sbjct: 1403 --VDSTVKVYITVLDENDNSPRFDFTSDS-AVSIPEDCPVGQRVATVKAWDPDAG-SNGQ 1458
Query: 364 LQFYVSDRSFLDKFAI----NNAGEVILRRSLDYETTSNYFYQVMVTDSISNDTAS---I 416
+ F ++ + F I ++ GEV + R LD E +Y QV+ +D + +
Sbjct: 1459 VVFSLASGNIAGAFEIVTTNDSIGEVFVARPLDREELDHYILQVVASDRGTPPRKKDHIL 1518
Query: 417 NISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAHD-GDAGTLALSLA-G 474
+++ D+N+ P P F D G L+ + G
Sbjct: 1519 QVTILDINDNPPVIESP---FGYNVSVNENVGGGTAVVQVRATDRDIGINSVLSYYITEG 1575
Query: 475 QHARMFYIN-ASGDLFLREEAIGNLNSSSLHLVATAIDSGIP 515
F ++ SG++ R S HLVAT D G P
Sbjct: 1576 NKDMAFRMDRISGEIATRPAPPDRERQSFYHLVATVEDEGTP 1617
Score = 44.8 bits (101), Expect = 0.001
Identities = 36/111 (32%), Positives = 50/111 (45%), Gaps = 7/111 (6%)
Query: 328 FTQKQYST--TVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGE 384
FT + T +SE GS + L + + PL F VS FA+ + G
Sbjct: 31 FTNHFFDTYLLISEDTPVGSSVTQLLAQDMDND----PLVFGVSGEEASRFFAVEPDTGV 86
Query: 385 VILRRSLDYETTSNYFYQVMVTDSISNDTASINISVEDVNEWEPRFRHPQY 435
V LR+ LD ET S + + V+D T +NI V DVN+ P F + Y
Sbjct: 87 VWLRQPLDRETKSEFTVEFSVSDHQGVITRKVNIQVGDVNDNAPTFHNQPY 137
>AL731541-6|CAI40841.1| 3359|Homo sapiens cadherin-like 23 protein.
Length = 3359
Score = 99.5 bits (237), Expect = 5e-20
Identities = 96/369 (26%), Positives = 156/369 (42%), Gaps = 28/369 (7%)
Query: 80 CDRRRTTDP-SFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQP 138
C R R P S + V +RV D+NDN P P + +SE SD D
Sbjct: 1827 CARDRGMPPLSSTMLVGIRVLDINDNDPVLLNLPMNITISENSPVSSFVAHVLASDADS- 1885
Query: 139 GPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYS- 197
G ++ L + + G + E F N I+ V +PLD E + + + + V+D P +
Sbjct: 1886 GCNARLTFNITAG-NRERAFFINATTGIVTVNRPLDRERIPEYKLTISVKDNPENPRIAR 1944
Query: 198 -DTTLQVTVL-DADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQ 255
D L + L D +D +P FT Y A + +++ GT LT GPI A D D I A +
Sbjct: 1945 RDYDLLLIFLSDENDNHPLFTKSTYQAEVMENSPAGTPLTVLNGPILALDADQDIYAVVT 2004
Query: 256 YSSTGDHKQLIVVNKDTGQVAATKQLIAELD----PSVTIVLKATQVD--NPDRYALATL 309
Y G L +N TG V +I + + P + ++L A + N + L T+
Sbjct: 2005 YQLLGAQSGLFDINSSTGVVTVRSGVIIDREAFSPPILELLLLAEDIGLLNSTAHLLITI 2064
Query: 310 XXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVS 369
F+ + + E PG +L +T +++ + Y
Sbjct: 2065 LDDNDNRPT---------FSPATLTVHLLENCPPGFSVLQVTATDEDSGLNGELV--YRI 2113
Query: 370 DRSFLDKFAINNAGEVIL--RRSLDYETTSNYFYQVMVTDSIS---NDTASINISVEDVN 424
+ D+F I+ VI ++D E +Y V+ TD + + TA + I ++D+N
Sbjct: 2114 EAGAQDRFLIHLVTGVIRVGNATIDREEQESYRLTVVATDRGTVPLSGTAIVTILIDDIN 2173
Query: 425 EWEPRFRHP 433
+ P F +P
Sbjct: 2174 DSRPEFLNP 2182
Score = 94.3 bits (224), Expect = 2e-18
Identities = 102/417 (24%), Positives = 179/417 (42%), Gaps = 26/417 (6%)
Query: 28 GDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEKIGPSNVYVNVRCDRRRTTD 87
G ++D D + QE AV I GS ++++ E + V ++V + +
Sbjct: 2218 GIVAKDDTDRLVPNQEDAFAVNINTGS---VMVKSPMNRELVATYEVTLSVIDNASDLPE 2274
Query: 88 PSFVIP---VSVRVWDVNDNAPQWE--GAPYAV-RVSETXXXXXXXXXXXXSDRDQPGPH 141
S +P ++V V DVNDN PQ++ G Y + R+ E D D+ G +
Sbjct: 2275 RSVSVPNAKLTVNVLDVNDNTPQFKPFGITYYMERILEGATPGTTLIAVAAVDPDK-GLN 2333
Query: 142 SALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTL 201
+ Y +L Y+ E+ ++ + +D+E V+ +R D GSPP ++ +
Sbjct: 2334 GLVTYTLLDLVPPGYVQLEDSSAGKVIANRTVDYEEVHWLNFTVRASDNGSPPRAAEIPV 2393
Query: 202 QVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGD 261
+ ++D +D NP F Y + +D GT + T ++A D D G A ++Y S GD
Sbjct: 2394 YLEIVDINDNNPIFDQPSYQEAVFEDVPVGTIILT----VTATDADSGNFALIEY-SLGD 2448
Query: 262 HKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNP-DRYALATLXXXXXXXXXXX 320
+ +N TG + L + + +L A DNP D +
Sbjct: 2449 GESKFAINPTTGDIYVLSSL--DREKKDHYILTALAKDNPGDVASNRRENSVQVVIQVLD 2506
Query: 321 XXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAIN 380
QF++ Q+ST+V E G+ ++T+ Q+ E L Y + ++ F ++
Sbjct: 2507 VNDCRPQFSKPQFSTSVYENEPAGTSVITMMATDQD-EGPNGELT-YSLEGPGVEAFHVD 2564
Query: 381 -NAGEVILRRSLDYETTSNYFYQVMVTDSISN---DTASINISVEDVNEWEPRFRHP 433
++G V +R L ++ + V+ TD T + + V DVN+ P F P
Sbjct: 2565 MDSGLVTTQRPL--QSYEKFSLTVVATDGGEPPLWGTTMLLVEVIDVNDNRPVFVRP 2619
Score = 92.7 bits (220), Expect = 5e-18
Identities = 101/454 (22%), Positives = 197/454 (43%), Gaps = 42/454 (9%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEK-- 68
+ ED P+G+II T++ S + I L + + I P + ++ +L +LDRE+K
Sbjct: 2416 VFEDVPVGTIILTVTATDADSGNFALIEYSLGDGESKFAINPTTGDIYVLSSLDREKKDH 2475
Query: 69 -----IGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXX 123
+ N +V +RR + + V ++V DVND PQ+ ++ V E
Sbjct: 2476 YILTALAKDNP-GDVASNRRENS-----VQVVIQVLDVNDCRPQFSKPQFSTSVYENEPA 2529
Query: 124 XXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTI 183
+D+D+ GP+ L Y+ L GP E + + ++ ++PL ++ F++
Sbjct: 2530 GTSVITMMATDQDE-GPNGELTYS-LEGPGVEAFHVDMD-SGLVTTQRPL--QSYEKFSL 2584
Query: 184 KLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISA 243
+ D G PPL+ T L V V+D +D P F +L E L ++ + A
Sbjct: 2585 TVVATDGGEPPLWGTTMLLVEVIDVNDNRPVFVRPPNGTIL--HIREEIPLRSNVYEVYA 2642
Query: 244 ADQDLGINAPLQYS--STGDHK--QLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVD 299
D+D G+N ++YS T ++ + +++ +G + ++L E +++L A+ +
Sbjct: 2643 TDKDEGLNGAVRYSFLKTAGNRDWEFFIIDPISGLIQTAQRLDRESQAVYSLILVASDLG 2702
Query: 300 NPDRY-ALATLXXXXXXXXXXXXXXXXLQFTQKQYS-TTVSEGASPGSVLLTLTTVPQNT 357
P Y + L QY TV E + G+++ +T
Sbjct: 2703 QPVPYETMQPLQVALEDIDDNEPLFVRPPKGSPQYQLLTVPEHSPRGTLVGNVTGAVDAD 2762
Query: 358 EFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVT----------- 406
E + + ++++ + F + G +++ R LD E + + + V +
Sbjct: 2763 EGPNAIVYYFIAAGNEEKNFHLQPDGCLLVLRDLDREREAIFSFIVKASSNRSWTPPRGP 2822
Query: 407 ----DSISNDT-ASINISVEDVNEWEPRFRHPQY 435
D +++ T + + +ED+N+ PRF +Y
Sbjct: 2823 SPTLDLVADLTLQEVRVVLEDINDQPPRFTKAEY 2856
Score = 92.3 bits (219), Expect = 7e-18
Identities = 102/442 (23%), Positives = 174/442 (39%), Gaps = 30/442 (6%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEKIG 70
ISEDTP+GS + L D D + +E + P + + L + LDRE K
Sbjct: 42 ISEDTPVGSSVTQLLAQ-DMDNDPLVFGVSGEEASRFFAVEPDTGVVWLRQPLDRETK-- 98
Query: 71 PSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXX 130
S V + V+++V DVNDNAP + PY+VR+ E
Sbjct: 99 -SEFTVEFSVSDHQGV---ITRKVNIQVGDVNDNAPTFHNQPYSVRIPEVGATGNTPVGT 154
Query: 131 XXSDRDQPGPHSALHYAVLPG--PHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQ 188
+ P +VL P S++ ++ I+ V + LD+ET + + +
Sbjct: 155 PIFIVNATDPDLGAGGSVLYSFQPPSQFFAIDS-ARGIVTVIRELDYETTQAYQLTVNAT 213
Query: 189 DQG-SPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQD 247
DQ + PL + L + + D D +P F Y+ + + + GT + I+A DQD
Sbjct: 214 DQDKTRPLSTLANLAIIITDVQDMDPIFINLPYSTNIYEHSPPGTTVRI----ITAIDQD 269
Query: 248 LGINAPLQY---SSTGDHKQLIVVNKDTGQVAATKQLIAE---LDPSVTIVLKATQVDNP 301
G + Y S G+ + ++ +G + L E + +K T++ N
Sbjct: 270 KGRPRGIGYTIVSVAGNTNSIFALDYISGVLTLNGLLDRENPLYSHGFILTVKGTEL-ND 328
Query: 302 DRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRE 361
DR +F +YS ++E A G L V E
Sbjct: 329 DRTPSDATVTTTFNILVIDINDNAPEFNSSEYSVAITELAQVGFALPLFIQVVDKDEGLN 388
Query: 362 SPLQFYV----SDRSFLDKFAINNAGEVILRRS--LDYETTSNYFYQVMVTDSISNDT-- 413
S + Y+ S + ++ ++ +R + LDYET Y + + +S+ +
Sbjct: 389 SMFEVYLVGNNSHHFIISPTSVQGKADIRIRVAIPLDYETVDRYDFDLFANESVPDHVGY 448
Query: 414 ASINISVEDVNEWEPRFRHPQY 435
A + I++ + N+ P F P Y
Sbjct: 449 AKVKITLINENDNRPIFSQPLY 470
Score = 84.2 bits (199), Expect = 2e-15
Identities = 105/449 (23%), Positives = 173/449 (38%), Gaps = 31/449 (6%)
Query: 91 VIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLP 150
+ V++ + D+NDN P W+ APY + + E D D G + L Y++ P
Sbjct: 766 IATVNITLLDINDNHPTWKDAPYYINLVEMTPPDSDVTTVVAVDPDL-GENGTLVYSIQP 824
Query: 151 GPHSEY-----LGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPL--YSDTTLQV 203
P+ Y G ++ + P E I + V D G PPL S T+ V
Sbjct: 825 -PNKFYSLNSTTGKIRTTHAMLDRENPDPHEAELMRKIVVSVTDCGRPPLKATSSATVFV 883
Query: 204 TVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQY-SSTGDH 262
+LD +D +P F + A + EG S + A D D G+N + Y G
Sbjct: 884 NLLDLNDNDPTFQNLPFVA----EVLEGIPAGVSIYQVVAIDLDEGLNGLVSYRMPVGMP 939
Query: 263 KQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXX 322
+ ++N +G V T +L E + + A+ P + + +TL
Sbjct: 940 RMDFLINSSSGVVVTTTELDRERIAEYQLRVVASDAGTPTKSSTSTLTIHVLDVNDETPT 999
Query: 323 XXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAINNA 382
F Y+ +VSE P + N + L ++++ + KF++
Sbjct: 1000 -----FFPAVYNVSVSEDV-PREFRVVWLNCTDNDVGLNAELSYFITGGNVDGKFSVGYR 1053
Query: 383 GEVILR-RSLDYETTSNYFYQVMVTDS-----ISNDTASINISVEDVNEWEPRFRHPQYE 436
V+ LD ETT+ Y + D+ TA++ ++V DVN+ P F YE
Sbjct: 1054 DAVVRTVVGLDRETTAAYMLILEAIDNGPVGKRHTGTATVFVTVLDVNDNRPIFLQSSYE 1113
Query: 437 FEXXXXXXXXXXXXXXXXXXXXVAHDGDAGTLALS-LAGQHARMFYINASGDLFLR-EEA 494
A +G+ G + L G H F I+ S L +R
Sbjct: 1114 ---ASVPEDIPEGHSILQLKATDADEGEFGRVWYRILHGNHGNNFRIHVSNGLLMRGPRP 1170
Query: 495 IGNLNSSSLHLVATAIDSGIPPRQTSVPV 523
+ +SS L+ A + + P ++SV V
Sbjct: 1171 LDRERNSSHVLIVEAYNHDLGPMRSSVRV 1199
Score = 81.0 bits (191), Expect = 2e-14
Identities = 113/480 (23%), Positives = 186/480 (38%), Gaps = 47/480 (9%)
Query: 63 LDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXX 122
+DREE+ + + V R T S V++ + D+ND+ P++ V V E+
Sbjct: 2137 IDREEQ---ESYRLTVVATDRGTVPLSGTAIVTILIDDINDSRPEFLNPIQTVSVLESAE 2193
Query: 123 XXXXXXXXXXSDRDQPGPHSALHYAVLPG--------PHSEYLGFENELEPIIVVKKPLD 174
D D P H + P+ E N ++VK P++
Sbjct: 2194 PGTVIANITAIDHDL-NPKLEYHIVGIVAKDDTDRLVPNQEDAFAVNINTGSVMVKSPMN 2252
Query: 175 FETVNNFTIKLRVQDQGSP-PLYS----DTTLQVTVLDADDQNPKFT---YEHYTALLPD 226
E V + + L V D S P S + L V VLD +D P+F +Y + +
Sbjct: 2253 RELVATYEVTLSVIDNASDLPERSVSVPNAKLTVNVLDVNDNTPQFKPFGITYYMERILE 2312
Query: 227 DAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDT--GQVAATKQLIAE 284
A GT L ++A D D G+N + Y+ V +D+ G+V A + + E
Sbjct: 2313 GATPGTTLIA----VAAVDPDKGLNGLVTYTLLDLVPPGYVQLEDSSAGKVIANRTVDYE 2368
Query: 285 LDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPG 344
+ ++A+ +P R A + F Q Y V E G
Sbjct: 2369 EVHWLNFTVRASDNGSPPRAAEIPVYLEIVDINDNNPI-----FDQPSYQEAVFEDVPVG 2423
Query: 345 SVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQV 403
+++LT+T ++ + +++ + D KFAIN G++ + SLD E +Y
Sbjct: 2424 TIILTVTATDADSG-NFALIEYSLGDGE--SKFAINPTTGDIYVLSSLDREKKDHYILTA 2480
Query: 404 MVTDS----ISN---DTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXX 456
+ D+ SN ++ + I V DVN+ P+F PQ+
Sbjct: 2481 LAKDNPGDVASNRRENSVQVVIQVLDVNDCRPQFSKPQFSTSVYENEPAGTSVITMMATD 2540
Query: 457 XXVAHDGDAGTLALSLAGQHARMFYINASGDLFLREEAIGNLNSSSLHLVATAIDSGIPP 516
+G G L SL G F+++ L + + + SL +VAT D G PP
Sbjct: 2541 QD---EGPNGELTYSLEGPGVEAFHVDMDSGLVTTQRPLQSYEKFSLTVVAT--DGGEPP 2595
Score = 80.6 bits (190), Expect = 2e-14
Identities = 106/480 (22%), Positives = 181/480 (37%), Gaps = 35/480 (7%)
Query: 57 LTLLRALDREEKIGPSNVYVNVRC----DRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAP 112
LTL LDRE + + V+ D R +D + ++ V D+NDNAP++ +
Sbjct: 300 LTLNGLLDRENPLYSHGFILTVKGTELNDDRTPSDATVTTTFNILVIDINDNAPEFNSSE 359
Query: 113 YAVRVSETXXXXXXX-XXXXXSDRDQPGPHSALHYAVLPGPHSEYL-----GFENELEPI 166
Y+V ++E D+D+ G +S L G +S + + + +
Sbjct: 360 YSVAITELAQVGFALPLFIQVVDKDE-GLNSMFE-VYLVGNNSHHFIISPTSVQGKADIR 417
Query: 167 IVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPD 226
I V PLD+ETV+ + L ++ P +++T+++ +D P F+ Y L +
Sbjct: 418 IRVAIPLDYETVDRYDFDL-FANESVPDHVGYAKVKITLINENDNRPIFSQPLYNISLYE 476
Query: 227 DAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLIAELD 286
+ GT + T + A D D G + Y + D + + +KDTG + +L EL
Sbjct: 477 NVTVGTSVLT----VLATDNDAGTFGEVSYFFSDDPDRFSL-DKDTGLIMLIARLDYELI 531
Query: 287 PSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSV 346
T+ + A + + F + Y + E +
Sbjct: 532 QRFTLTIIARDGGGEETTGRVRINVLDVNDNVPT-------FQKDAYVGALRENEPSVTQ 584
Query: 347 LLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAIN---NAGEVILRRSLDYETTSN--YFY 401
L+ L +++ VS +F F I+ G + + R LDYE SN +
Sbjct: 585 LVRLRATDEDSPPNNQITYSIVSASAFGSYFDISLYEGYGVISVSRPLDYEQISNGLIYL 644
Query: 402 QVMVTDSIS---NDTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXX 458
VM D+ + N T + I V D N+ P F P Y
Sbjct: 645 TVMAMDAGNPPLNSTVPVTIEVFDENDNPPTFSKPAYFVSVVENIMAGATVLFLNATDLD 704
Query: 459 VAHDGDAGTLALSLAGQHARMFYINASGDLFLREEAIGNLNSSSLHLVATAIDSGIPPRQ 518
+ + ++ SL G + F INA + S L+ A+D G+ Q
Sbjct: 705 RSREYGQESIIYSLEG--STQFRINARSGEITTTSLLDRETKSEYILIVRAVDGGVGHNQ 762
Score = 78.6 bits (185), Expect = 9e-14
Identities = 88/354 (24%), Positives = 153/354 (43%), Gaps = 31/354 (8%)
Query: 94 VSVRVWDVNDNAP----QWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVL 149
V V V D+NDN P +EG P+ V + DRD GP+ + Y+++
Sbjct: 1735 VLVNVNDINDNVPTFPRDYEG-PFEVTEGQPGPRVWTFLAH---DRDS-GPNGQVEYSIM 1789
Query: 150 PG-PHSEYLGFENELEPIIVVKKP--LDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVL 206
G P E++ + +E ++ V+K LD ET+ + + + +D+G PPL S + + VL
Sbjct: 1790 DGDPLGEFV--ISPVEGVLRVRKDVELDRETIAFYNLTICARDRGMPPLSSTMLVGIRVL 1847
Query: 207 DADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSST-GDHKQL 265
D +D +P + +++ +F+ + A+D D G NA L ++ T G+ ++
Sbjct: 1848 DINDNDPVLLNLPMNITISENSPVSSFV----AHVLASDADSGCNARLTFNITAGNRERA 1903
Query: 266 IVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXX 325
+N TG V + L E P + + DNP+ +A
Sbjct: 1904 FFINATTGIVTVNRPLDRERIPEYKLTISVK--DNPENPRIARRDYDLLLIFLSDENDNH 1961
Query: 326 LQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDR---SFLDKFAINNA 382
FT+ Y V E SP LT+ P + + V+ + + F IN++
Sbjct: 1962 PLFTKSTYQAEVMEN-SPAGTPLTVLNGPILALDADQDIYAVVTYQLLGAQSGLFDINSS 2020
Query: 383 GEVILRRS---LDYETTSNYFYQVMVTD---SISNDTASINISVEDVNEWEPRF 430
V+ RS +D E S ++++ + N TA + I++ D N+ P F
Sbjct: 2021 TGVVTVRSGVIIDREAFSPPILELLLLAEDIGLLNSTAHLLITILDDNDNRPTF 2074
Score = 77.0 bits (181), Expect = 3e-13
Identities = 81/352 (23%), Positives = 144/352 (40%), Gaps = 24/352 (6%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPG-P 152
V V + D+NDN P ++ P+ V E D D+ G + + Y + G P
Sbjct: 881 VFVNLLDLNDNDPTFQNLPFVAEVLEGIPAGVSIYQVVAIDLDE-GLNGLVSYRMPVGMP 939
Query: 153 HSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQN 212
++L N ++V LD E + + +++ D G+P S +TL + VLD +D+
Sbjct: 940 RMDFL--INSSSGVVVTTTELDRERIAEYQLRVVASDAGTPTKSSTSTLTIHVLDVNDET 997
Query: 213 PKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQ-LIVVNKD 271
P F Y + +D + ++ D D+G+NA L Y TG + V
Sbjct: 998 PTFFPAVYNVSVSEDVPREFRVVW----LNCTDNDVGLNAELSYFITGGNVDGKFSVGYR 1053
Query: 272 TGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQK 331
V L E + ++L+A +DN T + F Q
Sbjct: 1054 DAVVRTVVGLDRETTAAYMLILEA--IDNGPVGKRHTGTATVFVTVLDVNDNRPI-FLQS 1110
Query: 332 QYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILR--R 389
Y +V E G +L L + E + + + + + F I+ + +++R R
Sbjct: 1111 SYEASVPEDIPEGHSILQLKATDAD-EGEFGRVWYRILHGNHGNNFRIHVSNGLLMRGPR 1169
Query: 390 SLDYETTSNYFYQVMVTDSISND------TASINISVEDVNEWEPRFRHPQY 435
LD E S++ V++ ++ ++D + + + VED+N+ P F QY
Sbjct: 1170 PLDRERNSSH---VLIVEAYNHDLGPMRSSVRVIVYVEDINDEAPVFTQQQY 1218
Score = 74.1 bits (174), Expect = 2e-12
Identities = 83/355 (23%), Positives = 153/355 (43%), Gaps = 28/355 (7%)
Query: 92 IPVSVRVWDVNDNAPQWE-GAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLP 150
+ V + V D NDN+P+++ + AV + E D D G + + +++
Sbjct: 1407 VKVYITVLDENDNSPRFDFTSDSAVSIPEDCPVGQRVATVKAWDPDA-GSNGQVVFSLAS 1465
Query: 151 GPHSEYLGFENELEPI--IVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDA 208
G + + I + V +PLD E ++++ +++ D+G+PP D LQVT+LD
Sbjct: 1466 GNIAGAFEIVTTNDSIGEVFVARPLDREELDHYILQVVASDRGTPPRKKDHILQVTILDI 1525
Query: 209 DDQNPKFTYEH-YTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIV 267
+D P Y + ++ GT + + A D+D+GIN+ L Y T +K +
Sbjct: 1526 NDNPPVIESPFGYNVSVNENVGGGTAVV----QVRATDRDIGINSVLSYYITEGNKDMAF 1581
Query: 268 -VNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXL 326
+++ +G++ AT+ + + L AT D AT
Sbjct: 1582 RMDRISGEI-ATRPAPPDRERQSFYHLVATVEDEGTPTLSAT---THVYVTIVDENDNAP 1637
Query: 327 QFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESP---LQFYVSDRSFLDKFAIN-NA 382
F Q Y + EG P ++ +L T+ Q + E P + + + + ++ F I+ +
Sbjct: 1638 MFQQPHYEVLLDEG--PDTLNTSLITI-QALDLDEGPNGTVTYAIVAGNIVNTFRIDRHM 1694
Query: 383 GEVILRRSLDYETT-SNYFYQVMVTDSIS------NDTASINISVEDVNEWEPRF 430
G + + LDYE + Y V TD T ++ ++V D+N+ P F
Sbjct: 1695 GVITAAKELDYEISHGRYTLIVTATDQCPILSHRLTSTTTVLVNVNDINDNVPTF 1749
Score = 70.1 bits (164), Expect = 3e-11
Identities = 82/363 (22%), Positives = 148/363 (40%), Gaps = 33/363 (9%)
Query: 96 VRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSE 155
+ + D NDN P + A V + E +D D G + L Y + G
Sbjct: 2062 ITILDDNDNRPTFSPATLTVHLLENCPPGFSVLQVTATDEDS-GLNGELVYRIEAGAQDR 2120
Query: 156 YLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKF 215
+L I V +D E ++ + + D+G+ PL + + + D +D P+F
Sbjct: 2121 FL-IHLVTGVIRVGNATIDREEQESYRLTVVATDRGTVPLSGTAIVTILIDDINDSRPEF 2179
Query: 216 TYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTG-----DHKQLI---- 266
T + + AE GT + I+A D DL N L+Y G D +L+
Sbjct: 2180 LNPIQTVSVLESAEPGTVIAN----ITAIDHDL--NPKLEYHIVGIVAKDDTDRLVPNQE 2233
Query: 267 ---VVNKDTGQVAA----TKQLIAELDPSVTIVLKATQVDNPDR-YALATLXXXXXXXXX 318
VN +TG V ++L+A + +++++ A+ D P+R ++
Sbjct: 2234 DAFAVNINTGSVMVKSPMNRELVATYEVTLSVIDNAS--DLPERSVSVPNAKLTVNVLDV 2291
Query: 319 XXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSD--RSFLDK 376
F Y + EGA+PG+ L+ + V + + + + D +
Sbjct: 2292 NDNTPQFKPFGITYYMERILEGATPGTTLIAVAAVDPDKGL-NGLVTYTLLDLVPPGYVQ 2350
Query: 377 FAINNAGEVILRRSLDYETTSNYFYQVMVTDSISNDTAS---INISVEDVNEWEPRFRHP 433
++AG+VI R++DYE + V +D+ S A+ + + + D+N+ P F P
Sbjct: 2351 LEDSSAGKVIANRTVDYEEVHWLNFTVRASDNGSPPRAAEIPVYLEIVDINDNNPIFDQP 2410
Query: 434 QYE 436
Y+
Sbjct: 2411 SYQ 2413
Score = 66.5 bits (155), Expect = 4e-10
Identities = 83/392 (21%), Positives = 146/392 (37%), Gaps = 17/392 (4%)
Query: 48 VGIVPGSKNLTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQ 107
+ + G +++ R LD E+ I +Y+ V + +PV++ V+D NDN P
Sbjct: 617 ISLYEGYGVISVSRPLDYEQ-ISNGLIYLTVMAMDAGNPPLNSTVPVTIEVFDENDNPPT 675
Query: 108 WEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPII 167
+ Y V V E +D D+ + +++ N I
Sbjct: 676 FSKPAYFVSVVENIMAGATVLFLNATDLDRSREYG--QESIIYSLEGSTQFRINARSGEI 733
Query: 168 VVKKPLDFETVNNFTIKLRVQD--QGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLP 225
LD ET + + + +R D G T+ +T+LD +D +P + Y L
Sbjct: 734 TTTSLLDRETKSEYILIVRAVDGGVGHNQKTGIATVNITLLDINDNHPTWKDAPYYINLV 793
Query: 226 DDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLI--A 283
+ + +TT + A D DLG N L YS +K +N TG++ T ++
Sbjct: 794 EMTPPDSDVTT----VVAVDPDLGENGTLVYSIQPPNK-FYSLNSTTGKIRTTHAMLDRE 848
Query: 284 ELDPSVTIVLKATQVDNPD--RYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGA 341
DP +++ V D R L F + V EG
Sbjct: 849 NPDPHEAELMRKIVVSVTDCGRPPLKATSSATVFVNLLDLNDNDPTFQNLPFVAEVLEGI 908
Query: 342 SPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFY 401
G + + + + +D +++G V+ LD E + Y
Sbjct: 909 PAGVSIYQVVAIDLDEGLNGLVSYRMPVGMPRMDFLINSSSGVVVTTTELDRERIAEYQL 968
Query: 402 QVMVTDS---ISNDTASINISVEDVNEWEPRF 430
+V+ +D+ + T+++ I V DVN+ P F
Sbjct: 969 RVVASDAGTPTKSSTSTLTIHVLDVNDETPTF 1000
Score = 64.1 bits (149), Expect = 2e-09
Identities = 53/222 (23%), Positives = 94/222 (42%), Gaps = 10/222 (4%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVL-PGP 152
V + V DVNDN P ++ Y + E +D D P P++ + Y+++
Sbjct: 552 VRINVLDVNDNVPTFQKDAYVGALRENEPSVTQLVRLRATDEDSP-PNNQITYSIVSASA 610
Query: 153 HSEYLGFE-NELEPIIVVKKPLDFETVNNFTIKLRV--QDQGSPPLYSDTTLQVTVLDAD 209
Y E +I V +PLD+E ++N I L V D G+PPL S + + V D +
Sbjct: 611 FGSYFDISLYEGYGVISVSRPLDYEQISNGLIYLTVMAMDAGNPPLNSTVPVTIEVFDEN 670
Query: 210 DQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVN 269
D P F+ Y + ++ G + ++ G + YS G + +N
Sbjct: 671 DNPPTFSKPAYFVSVVENIMAGATVLFLNATDLDRSREYG-QESIIYSLEGSTQ--FRIN 727
Query: 270 KDTGQVAATKQLIAELDPSVTIVLKATQ--VDNPDRYALATL 309
+G++ T L E ++++A V + + +AT+
Sbjct: 728 ARSGEITTTSLLDRETKSEYILIVRAVDGGVGHNQKTGIATV 769
Score = 62.1 bits (144), Expect = 9e-09
Identities = 90/364 (24%), Positives = 150/364 (41%), Gaps = 28/364 (7%)
Query: 85 TTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSAL 144
T S +++ V DVND P + A Y V VSE +D D G ++ L
Sbjct: 977 TPTKSSTSTLTIHVLDVNDETPTFFPAVYNVSVSEDVPREFRVVWLNCTDND-VGLNAEL 1035
Query: 145 HYAVLPG--PHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGS-PPLYSDT-T 200
Y + G +G+ + + +V LD ET + + L D G ++ T T
Sbjct: 1036 SYFITGGNVDGKFSVGYRDAVVRTVV---GLDRETTAAYMLILEAIDNGPVGKRHTGTAT 1092
Query: 201 LQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSST- 259
+ VTVLD +D P F Y A +P+D EG + + A D D G + Y
Sbjct: 1093 VFVTVLDVNDNRPIFLQSSYEASVPEDIPEGHSIL----QLKATDADEGEFGRVWYRILH 1148
Query: 260 GDHKQLIVVNKDTG-QVAATKQLIAELDPSVTIVLKATQVD-NPDRYALATLXXXXXXXX 317
G+H ++ G + + L E + S ++++A D P R ++ +
Sbjct: 1149 GNHGNNFRIHVSNGLLMRGPRPLDRERNSSHVLIVEAYNHDLGPMRSSVRVIVYVEDIND 1208
Query: 318 XXXXXXXXLQFTQKQYSTT-VSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDK 376
FTQ+QYS + E A G+ ++ + +++ + L Y K
Sbjct: 1209 EAPV------FTQQQYSRLGLRETAGIGTSVIVVQATDRDS--GDGGLVNYRILSGAEGK 1260
Query: 377 FAIN-NAGEVILRRSLDYETTSNYFYQVMVTDS---ISNDTASINISVEDVNEWEPRFRH 432
F I+ + G +I LDYET ++Y V TD + S+ I++ + + +F +
Sbjct: 1261 FEIDESTGLIITVNYLDYETKTSYMMNVSATDQAPPFNQGFCSVYITLLNELDEAVQFSN 1320
Query: 433 PQYE 436
YE
Sbjct: 1321 ASYE 1324
Score = 57.2 bits (132), Expect = 2e-07
Identities = 59/281 (20%), Positives = 123/281 (43%), Gaps = 20/281 (7%)
Query: 166 IIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTAL-L 224
+I V+ +D E + +T+ + V D G P + S + +TVLD +D +P+F + +A+ +
Sbjct: 1375 VITVQGLVDREKGDFYTLTV-VADDGGPKVDSTVKVYITVLDENDNSPRFDFTSDSAVSI 1433
Query: 225 PDDAEEGTFLTTSPGPISAADQDLGINAPLQYS-STGDHK---QLIVVNKDTGQVAATKQ 280
P+D G + T + A D D G N + +S ++G+ +++ N G+V +
Sbjct: 1434 PEDCPVGQRVAT----VKAWDPDAGSNGQVVFSLASGNIAGAFEIVTTNDSIGEVFVARP 1489
Query: 281 LIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEG 340
L E + + A+ P R L + Y+ +V+E
Sbjct: 1490 LDREELDHYILQVVASDRGTPPRKKDHILQVTILDINDNPPVIE----SPFGYNVSVNEN 1545
Query: 341 ASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAINN-AGEVILRRSLDYETTSNY 399
G+ ++ + ++ S L +Y+++ + F ++ +GE+ R + ++
Sbjct: 1546 VGGGTAVVQVRATDRDIGIN-SVLSYYITEGNKDMAFRMDRISGEIATRPAPPDRERQSF 1604
Query: 400 FYQVMVTDSISNDTAS----INISVEDVNEWEPRFRHPQYE 436
++ V + T S + +++ D N+ P F+ P YE
Sbjct: 1605 YHLVATVEDEGTPTLSATTHVYVTIVDENDNAPMFQQPHYE 1645
Score = 56.0 bits (129), Expect = 6e-07
Identities = 74/355 (20%), Positives = 144/355 (40%), Gaps = 30/355 (8%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
V + + + NDN P + Y + + E +D D G + Y P
Sbjct: 451 VKITLINENDNRPIFSQPLYNISLYENVTVGTSVLTVLATDNDA-GTFGEVSYFFSDDP- 508
Query: 154 SEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNP 213
+ + + I+++ + LD+E + FT+ + +D G + +++ VLD +D P
Sbjct: 509 -DRFSLDKDTGLIMLIAR-LDYELIQRFTLTIIARDGGGEE--TTGRVRINVLDVNDNVP 564
Query: 214 KFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQY-----SSTGDHKQLIVV 268
F + Y L ++ T L + A D+D N + Y S+ G + I +
Sbjct: 565 TFQKDAYVGALRENEPSVTQLVR----LRATDEDSPPNNQITYSIVSASAFGSYFD-ISL 619
Query: 269 NKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQF 328
+ G ++ ++ L E + I L +D + +T+ F
Sbjct: 620 YEGYGVISVSRPLDYEQISNGLIYLTVMAMDAGNPPLNSTVPVTIEVFDENDNPPT---F 676
Query: 329 TQKQYSTTVSEGASPGSVLLTL--TTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEV 385
++ Y +V E G+ +L L T + ++ E+ + + + + + +F IN +GE+
Sbjct: 677 SKPAYFVSVVENIMAGATVLFLNATDLDRSREYGQESIIYSLEGST---QFRINARSGEI 733
Query: 386 ILRRSLDYETTSNYFYQVMVTD-----SISNDTASINISVEDVNEWEPRFRHPQY 435
LD ET S Y V D + A++NI++ D+N+ P ++ Y
Sbjct: 734 TTTSLLDRETKSEYILIVRAVDGGVGHNQKTGIATVNITLLDINDNHPTWKDAPY 788
Score = 54.0 bits (124), Expect = 2e-06
Identities = 66/247 (26%), Positives = 110/247 (44%), Gaps = 29/247 (11%)
Query: 50 IVPGSKNLTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQW- 108
I P S + + LDRE + S + V D + + P+ V + D++DN P +
Sbjct: 2671 IDPISGLIQTAQRLDRESQAVYSLILV--ASDLGQPVPYETMQPLQVALEDIDDNEPLFV 2728
Query: 109 ---EGAPY--AVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENEL 163
+G+P + V E + GP++ ++Y + G +E F +
Sbjct: 2729 RPPKGSPQYQLLTVPEHSPRGTLVGNVTGAVDADEGPNAIVYYFIAAG--NEEKNFHLQP 2786
Query: 164 EPIIVVKKPLDFE--TVNNFTIKLRVQDQGSPP--------LYSDTTLQ---VTVLDADD 210
+ ++V + LD E + +F +K +PP L +D TLQ V + D +D
Sbjct: 2787 DGCLLVLRDLDREREAIFSFIVKASSNRSWTPPRGPSPTLDLVADLTLQEVRVVLEDIND 2846
Query: 211 QNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDH--KQLIVV 268
Q P+FT YTA + DA+ G+ L + A D D+G N+ + YS H + L
Sbjct: 2847 QPPRFTKAEYTAGVATDAKVGSELI----QVLALDADIGNNSLVFYSILAIHYFRALAND 2902
Query: 269 NKDTGQV 275
++D GQV
Sbjct: 2903 SEDVGQV 2909
Score = 51.2 bits (117), Expect = 2e-05
Identities = 111/522 (21%), Positives = 189/522 (36%), Gaps = 37/522 (7%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRA---LDREE 67
+ ED P G I L + G + R+ N L+R LDRE
Sbjct: 1116 VPEDIPEGHSILQLKATDADEGEFGRVWYRILHGNHGNNFRIHVSNGLLMRGPRPLDRER 1175
Query: 68 KIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYA-VRVSETXXXXXX 126
S+V + V + V V V D+ND AP + Y+ + + ET
Sbjct: 1176 N--SSHVLI-VEAYNHDLGPMRSSVRVIVYVEDINDEAPVFTQQQYSRLGLRETAGIGTS 1232
Query: 127 XXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFE-NELEPIIVVKKPLDFETVNNFTIKL 185
+DRD G ++Y +L G + FE +E +I+ LD+ET ++ + +
Sbjct: 1233 VIVVQATDRDS-GDGGLVNYRILSGAEGK---FEIDESTGLIITVNYLDYETKTSYMMNV 1288
Query: 186 RVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGT-FLTTSPGPISAA 244
DQ P ++ +T+L+ D+ +F+ Y A + ++ GT + I
Sbjct: 1289 SATDQAPPFNQGFCSVYITLLNELDEAVQFSNASYEAAILENLALGTEIVRVQAYSIDNL 1348
Query: 245 DQ-DLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDR 303
+Q NA Y+ST K L ++ TG + T Q + + + L D +
Sbjct: 1349 NQITYRFNA---YTST-QAKALFKIDAITGVI--TVQGLVDREKGDFYTLTVVADDGGPK 1402
Query: 304 YALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESP 363
+ + FT + ++ E G + T+ +
Sbjct: 1403 --VDSTVKVYITVLDENDNSPRFDFTSDS-AVSIPEDCPVGQRVATVKAWDPDAG-SNGQ 1458
Query: 364 LQFYVSDRSFLDKFAI----NNAGEVILRRSLDYETTSNYFYQVMVTDSISNDTAS---I 416
+ F ++ + F I ++ GEV + R LD E +Y QV+ +D + +
Sbjct: 1459 VVFSLASGNIAGAFEIVTTNDSIGEVFVARPLDREELDHYILQVVASDRGTPPRKKDHIL 1518
Query: 417 NISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAHD-GDAGTLALSLA-G 474
+++ D+N+ P P F D G L+ + G
Sbjct: 1519 QVTILDINDNPPVIESP---FGYNVSVNENVGGGTAVVQVRATDRDIGINSVLSYYITEG 1575
Query: 475 QHARMFYIN-ASGDLFLREEAIGNLNSSSLHLVATAIDSGIP 515
F ++ SG++ R S HLVAT D G P
Sbjct: 1576 NKDMAFRMDRISGEIATRPAPPDRERQSFYHLVATVEDEGTP 1617
Score = 44.8 bits (101), Expect = 0.001
Identities = 36/111 (32%), Positives = 50/111 (45%), Gaps = 7/111 (6%)
Query: 328 FTQKQYST--TVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGE 384
FT + T +SE GS + L + + PL F VS FA+ + G
Sbjct: 31 FTNHFFDTYLLISEDTPVGSSVTQLLAQDMDND----PLVFGVSGEEASRFFAVEPDTGV 86
Query: 385 VILRRSLDYETTSNYFYQVMVTDSISNDTASINISVEDVNEWEPRFRHPQY 435
V LR+ LD ET S + + V+D T +NI V DVN+ P F + Y
Sbjct: 87 VWLRQPLDRETKSEFTVEFSVSDHQGVITRKVNIQVGDVNDNAPTFHNQPY 137
>AL359183-3|CAI13426.1| 3359|Homo sapiens cadherin-like 23 protein.
Length = 3359
Score = 99.5 bits (237), Expect = 5e-20
Identities = 96/369 (26%), Positives = 156/369 (42%), Gaps = 28/369 (7%)
Query: 80 CDRRRTTDP-SFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQP 138
C R R P S + V +RV D+NDN P P + +SE SD D
Sbjct: 1827 CARDRGMPPLSSTMLVGIRVLDINDNDPVLLNLPMNITISENSPVSSFVAHVLASDADS- 1885
Query: 139 GPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYS- 197
G ++ L + + G + E F N I+ V +PLD E + + + + V+D P +
Sbjct: 1886 GCNARLTFNITAG-NRERAFFINATTGIVTVNRPLDRERIPEYKLTISVKDNPENPRIAR 1944
Query: 198 -DTTLQVTVL-DADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQ 255
D L + L D +D +P FT Y A + +++ GT LT GPI A D D I A +
Sbjct: 1945 RDYDLLLIFLSDENDNHPLFTKSTYQAEVMENSPAGTPLTVLNGPILALDADQDIYAVVT 2004
Query: 256 YSSTGDHKQLIVVNKDTGQVAATKQLIAELD----PSVTIVLKATQVD--NPDRYALATL 309
Y G L +N TG V +I + + P + ++L A + N + L T+
Sbjct: 2005 YQLLGAQSGLFDINSSTGVVTVRSGVIIDREAFSPPILELLLLAEDIGLLNSTAHLLITI 2064
Query: 310 XXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVS 369
F+ + + E PG +L +T +++ + Y
Sbjct: 2065 LDDNDNRPT---------FSPATLTVHLLENCPPGFSVLQVTATDEDSGLNGELV--YRI 2113
Query: 370 DRSFLDKFAINNAGEVIL--RRSLDYETTSNYFYQVMVTDSIS---NDTASINISVEDVN 424
+ D+F I+ VI ++D E +Y V+ TD + + TA + I ++D+N
Sbjct: 2114 EAGAQDRFLIHLVTGVIRVGNATIDREEQESYRLTVVATDRGTVPLSGTAIVTILIDDIN 2173
Query: 425 EWEPRFRHP 433
+ P F +P
Sbjct: 2174 DSRPEFLNP 2182
Score = 94.3 bits (224), Expect = 2e-18
Identities = 102/417 (24%), Positives = 179/417 (42%), Gaps = 26/417 (6%)
Query: 28 GDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEKIGPSNVYVNVRCDRRRTTD 87
G ++D D + QE AV I GS ++++ E + V ++V + +
Sbjct: 2218 GIVAKDDTDRLVPNQEDAFAVNINTGS---VMVKSPMNRELVATYEVTLSVIDNASDLPE 2274
Query: 88 PSFVIP---VSVRVWDVNDNAPQWE--GAPYAV-RVSETXXXXXXXXXXXXSDRDQPGPH 141
S +P ++V V DVNDN PQ++ G Y + R+ E D D+ G +
Sbjct: 2275 RSVSVPNAKLTVNVLDVNDNTPQFKPFGITYYMERILEGATPGTTLIAVAAVDPDK-GLN 2333
Query: 142 SALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTL 201
+ Y +L Y+ E+ ++ + +D+E V+ +R D GSPP ++ +
Sbjct: 2334 GLVTYTLLDLVPPGYVQLEDSSAGKVIANRTVDYEEVHWLNFTVRASDNGSPPRAAEIPV 2393
Query: 202 QVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGD 261
+ ++D +D NP F Y + +D GT + T ++A D D G A ++Y S GD
Sbjct: 2394 YLEIVDINDNNPIFDQPSYQEAVFEDVPVGTIILT----VTATDADSGNFALIEY-SLGD 2448
Query: 262 HKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNP-DRYALATLXXXXXXXXXXX 320
+ +N TG + L + + +L A DNP D +
Sbjct: 2449 GESKFAINPTTGDIYVLSSL--DREKKDHYILTALAKDNPGDVASNRRENSVQVVIQVLD 2506
Query: 321 XXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAIN 380
QF++ Q+ST+V E G+ ++T+ Q+ E L Y + ++ F ++
Sbjct: 2507 VNDCRPQFSKPQFSTSVYENEPAGTSVITMMATDQD-EGPNGELT-YSLEGPGVEAFHVD 2564
Query: 381 -NAGEVILRRSLDYETTSNYFYQVMVTDSISN---DTASINISVEDVNEWEPRFRHP 433
++G V +R L ++ + V+ TD T + + V DVN+ P F P
Sbjct: 2565 MDSGLVTTQRPL--QSYEKFSLTVVATDGGEPPLWGTTMLLVEVIDVNDNRPVFVRP 2619
Score = 92.7 bits (220), Expect = 5e-18
Identities = 101/454 (22%), Positives = 197/454 (43%), Gaps = 42/454 (9%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEK-- 68
+ ED P+G+II T++ S + I L + + I P + ++ +L +LDRE+K
Sbjct: 2416 VFEDVPVGTIILTVTATDADSGNFALIEYSLGDGESKFAINPTTGDIYVLSSLDREKKDH 2475
Query: 69 -----IGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXX 123
+ N +V +RR + + V ++V DVND PQ+ ++ V E
Sbjct: 2476 YILTALAKDNP-GDVASNRRENS-----VQVVIQVLDVNDCRPQFSKPQFSTSVYENEPA 2529
Query: 124 XXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTI 183
+D+D+ GP+ L Y+ L GP E + + ++ ++PL ++ F++
Sbjct: 2530 GTSVITMMATDQDE-GPNGELTYS-LEGPGVEAFHVDMD-SGLVTTQRPL--QSYEKFSL 2584
Query: 184 KLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISA 243
+ D G PPL+ T L V V+D +D P F +L E L ++ + A
Sbjct: 2585 TVVATDGGEPPLWGTTMLLVEVIDVNDNRPVFVRPPNGTIL--HIREEIPLRSNVYEVYA 2642
Query: 244 ADQDLGINAPLQYS--STGDHK--QLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVD 299
D+D G+N ++YS T ++ + +++ +G + ++L E +++L A+ +
Sbjct: 2643 TDKDEGLNGAVRYSFLKTAGNRDWEFFIIDPISGLIQTAQRLDRESQAVYSLILVASDLG 2702
Query: 300 NPDRY-ALATLXXXXXXXXXXXXXXXXLQFTQKQYS-TTVSEGASPGSVLLTLTTVPQNT 357
P Y + L QY TV E + G+++ +T
Sbjct: 2703 QPVPYETMQPLQVALEDIDDNEPLFVRPPKGSPQYQLLTVPEHSPRGTLVGNVTGAVDAD 2762
Query: 358 EFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVT----------- 406
E + + ++++ + F + G +++ R LD E + + + V +
Sbjct: 2763 EGPNAIVYYFIAAGNEEKNFHLQPDGCLLVLRDLDREREAIFSFIVKASSNRSWTPPRGP 2822
Query: 407 ----DSISNDT-ASINISVEDVNEWEPRFRHPQY 435
D +++ T + + +ED+N+ PRF +Y
Sbjct: 2823 SPTLDLVADLTLQEVRVVLEDINDQPPRFTKAEY 2856
Score = 92.3 bits (219), Expect = 7e-18
Identities = 102/442 (23%), Positives = 174/442 (39%), Gaps = 30/442 (6%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEKIG 70
ISEDTP+GS + L D D + +E + P + + L + LDRE K
Sbjct: 42 ISEDTPVGSSVTQLLAQ-DMDNDPLVFGVSGEEASRFFAVEPDTGVVWLRQPLDRETK-- 98
Query: 71 PSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXX 130
S V + V+++V DVNDNAP + PY+VR+ E
Sbjct: 99 -SEFTVEFSVSDHQGV---ITRKVNIQVGDVNDNAPTFHNQPYSVRIPEVGATGNTPVGT 154
Query: 131 XXSDRDQPGPHSALHYAVLPG--PHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQ 188
+ P +VL P S++ ++ I+ V + LD+ET + + +
Sbjct: 155 PIFIVNATDPDLGAGGSVLYSFQPPSQFFAIDS-ARGIVTVIRELDYETTQAYQLTVNAT 213
Query: 189 DQG-SPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQD 247
DQ + PL + L + + D D +P F Y+ + + + GT + I+A DQD
Sbjct: 214 DQDKTRPLSTLANLAIIITDVQDMDPIFINLPYSTNIYEHSPPGTTVRI----ITAIDQD 269
Query: 248 LGINAPLQY---SSTGDHKQLIVVNKDTGQVAATKQLIAE---LDPSVTIVLKATQVDNP 301
G + Y S G+ + ++ +G + L E + +K T++ N
Sbjct: 270 KGRPRGIGYTIVSVAGNTNSIFALDYISGVLTLNGLLDRENPLYSHGFILTVKGTEL-ND 328
Query: 302 DRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRE 361
DR +F +YS ++E A G L V E
Sbjct: 329 DRTPSDATVTTTFNILVIDINDNAPEFNSSEYSVAITELAQVGFALPLFIQVVDKDEGLN 388
Query: 362 SPLQFYV----SDRSFLDKFAINNAGEVILRRS--LDYETTSNYFYQVMVTDSISNDT-- 413
S + Y+ S + ++ ++ +R + LDYET Y + + +S+ +
Sbjct: 389 SMFEVYLVGNNSHHFIISPTSVQGKADIRIRVAIPLDYETVDRYDFDLFANESVPDHVGY 448
Query: 414 ASINISVEDVNEWEPRFRHPQY 435
A + I++ + N+ P F P Y
Sbjct: 449 AKVKITLINENDNRPIFSQPLY 470
Score = 84.2 bits (199), Expect = 2e-15
Identities = 105/449 (23%), Positives = 173/449 (38%), Gaps = 31/449 (6%)
Query: 91 VIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLP 150
+ V++ + D+NDN P W+ APY + + E D D G + L Y++ P
Sbjct: 766 IATVNITLLDINDNHPTWKDAPYYINLVEMTPPDSDVTTVVAVDPDL-GENGTLVYSIQP 824
Query: 151 GPHSEY-----LGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPL--YSDTTLQV 203
P+ Y G ++ + P E I + V D G PPL S T+ V
Sbjct: 825 -PNKFYSLNSTTGKIRTTHAMLDRENPDPHEAELMRKIVVSVTDCGRPPLKATSSATVFV 883
Query: 204 TVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQY-SSTGDH 262
+LD +D +P F + A + EG S + A D D G+N + Y G
Sbjct: 884 NLLDLNDNDPTFQNLPFVA----EVLEGIPAGVSIYQVVAIDLDEGLNGLVSYRMPVGMP 939
Query: 263 KQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXX 322
+ ++N +G V T +L E + + A+ P + + +TL
Sbjct: 940 RMDFLINSSSGVVVTTTELDRERIAEYQLRVVASDAGTPTKSSTSTLTIHVLDVNDETPT 999
Query: 323 XXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAINNA 382
F Y+ +VSE P + N + L ++++ + KF++
Sbjct: 1000 -----FFPAVYNVSVSEDV-PREFRVVWLNCTDNDVGLNAELSYFITGGNVDGKFSVGYR 1053
Query: 383 GEVILR-RSLDYETTSNYFYQVMVTDS-----ISNDTASINISVEDVNEWEPRFRHPQYE 436
V+ LD ETT+ Y + D+ TA++ ++V DVN+ P F YE
Sbjct: 1054 DAVVRTVVGLDRETTAAYMLILEAIDNGPVGKRHTGTATVFVTVLDVNDNRPIFLQSSYE 1113
Query: 437 FEXXXXXXXXXXXXXXXXXXXXVAHDGDAGTLALS-LAGQHARMFYINASGDLFLR-EEA 494
A +G+ G + L G H F I+ S L +R
Sbjct: 1114 ---ASVPEDIPEGHSILQLKATDADEGEFGRVWYRILHGNHGNNFRIHVSNGLLMRGPRP 1170
Query: 495 IGNLNSSSLHLVATAIDSGIPPRQTSVPV 523
+ +SS L+ A + + P ++SV V
Sbjct: 1171 LDRERNSSHVLIVEAYNHDLGPMRSSVRV 1199
Score = 81.0 bits (191), Expect = 2e-14
Identities = 113/480 (23%), Positives = 186/480 (38%), Gaps = 47/480 (9%)
Query: 63 LDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXX 122
+DREE+ + + V R T S V++ + D+ND+ P++ V V E+
Sbjct: 2137 IDREEQ---ESYRLTVVATDRGTVPLSGTAIVTILIDDINDSRPEFLNPIQTVSVLESAE 2193
Query: 123 XXXXXXXXXXSDRDQPGPHSALHYAVLPG--------PHSEYLGFENELEPIIVVKKPLD 174
D D P H + P+ E N ++VK P++
Sbjct: 2194 PGTVIANITAIDHDL-NPKLEYHIVGIVAKDDTDRLVPNQEDAFAVNINTGSVMVKSPMN 2252
Query: 175 FETVNNFTIKLRVQDQGSP-PLYS----DTTLQVTVLDADDQNPKFT---YEHYTALLPD 226
E V + + L V D S P S + L V VLD +D P+F +Y + +
Sbjct: 2253 RELVATYEVTLSVIDNASDLPERSVSVPNAKLTVNVLDVNDNTPQFKPFGITYYMERILE 2312
Query: 227 DAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDT--GQVAATKQLIAE 284
A GT L ++A D D G+N + Y+ V +D+ G+V A + + E
Sbjct: 2313 GATPGTTLIA----VAAVDPDKGLNGLVTYTLLDLVPPGYVQLEDSSAGKVIANRTVDYE 2368
Query: 285 LDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPG 344
+ ++A+ +P R A + F Q Y V E G
Sbjct: 2369 EVHWLNFTVRASDNGSPPRAAEIPVYLEIVDINDNNPI-----FDQPSYQEAVFEDVPVG 2423
Query: 345 SVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQV 403
+++LT+T ++ + +++ + D KFAIN G++ + SLD E +Y
Sbjct: 2424 TIILTVTATDADSG-NFALIEYSLGDGE--SKFAINPTTGDIYVLSSLDREKKDHYILTA 2480
Query: 404 MVTDS----ISN---DTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXX 456
+ D+ SN ++ + I V DVN+ P+F PQ+
Sbjct: 2481 LAKDNPGDVASNRRENSVQVVIQVLDVNDCRPQFSKPQFSTSVYENEPAGTSVITMMATD 2540
Query: 457 XXVAHDGDAGTLALSLAGQHARMFYINASGDLFLREEAIGNLNSSSLHLVATAIDSGIPP 516
+G G L SL G F+++ L + + + SL +VAT D G PP
Sbjct: 2541 QD---EGPNGELTYSLEGPGVEAFHVDMDSGLVTTQRPLQSYEKFSLTVVAT--DGGEPP 2595
Score = 80.6 bits (190), Expect = 2e-14
Identities = 106/480 (22%), Positives = 181/480 (37%), Gaps = 35/480 (7%)
Query: 57 LTLLRALDREEKIGPSNVYVNVRC----DRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAP 112
LTL LDRE + + V+ D R +D + ++ V D+NDNAP++ +
Sbjct: 300 LTLNGLLDRENPLYSHGFILTVKGTELNDDRTPSDATVTTTFNILVIDINDNAPEFNSSE 359
Query: 113 YAVRVSETXXXXXXX-XXXXXSDRDQPGPHSALHYAVLPGPHSEYL-----GFENELEPI 166
Y+V ++E D+D+ G +S L G +S + + + +
Sbjct: 360 YSVAITELAQVGFALPLFIQVVDKDE-GLNSMFE-VYLVGNNSHHFIISPTSVQGKADIR 417
Query: 167 IVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPD 226
I V PLD+ETV+ + L ++ P +++T+++ +D P F+ Y L +
Sbjct: 418 IRVAIPLDYETVDRYDFDL-FANESVPDHVGYAKVKITLINENDNRPIFSQPLYNISLYE 476
Query: 227 DAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLIAELD 286
+ GT + T + A D D G + Y + D + + +KDTG + +L EL
Sbjct: 477 NVTVGTSVLT----VLATDNDAGTFGEVSYFFSDDPDRFSL-DKDTGLIMLIARLDYELI 531
Query: 287 PSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSV 346
T+ + A + + F + Y + E +
Sbjct: 532 QRFTLTIIARDGGGEETTGRVRINVLDVNDNVPT-------FQKDAYVGALRENEPSVTQ 584
Query: 347 LLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAIN---NAGEVILRRSLDYETTSN--YFY 401
L+ L +++ VS +F F I+ G + + R LDYE SN +
Sbjct: 585 LVRLRATDEDSPPNNQITYSIVSASAFGSYFDISLYEGYGVISVSRPLDYEQISNGLIYL 644
Query: 402 QVMVTDSIS---NDTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXX 458
VM D+ + N T + I V D N+ P F P Y
Sbjct: 645 TVMAMDAGNPPLNSTVPVTIEVFDENDNPPTFSKPAYFVSVVENIMAGATVLFLNATDLD 704
Query: 459 VAHDGDAGTLALSLAGQHARMFYINASGDLFLREEAIGNLNSSSLHLVATAIDSGIPPRQ 518
+ + ++ SL G + F INA + S L+ A+D G+ Q
Sbjct: 705 RSREYGQESIIYSLEG--STQFRINARSGEITTTSLLDRETKSEYILIVRAVDGGVGHNQ 762
Score = 78.6 bits (185), Expect = 9e-14
Identities = 88/354 (24%), Positives = 153/354 (43%), Gaps = 31/354 (8%)
Query: 94 VSVRVWDVNDNAP----QWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVL 149
V V V D+NDN P +EG P+ V + DRD GP+ + Y+++
Sbjct: 1735 VLVNVNDINDNVPTFPRDYEG-PFEVTEGQPGPRVWTFLAH---DRDS-GPNGQVEYSIM 1789
Query: 150 PG-PHSEYLGFENELEPIIVVKKP--LDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVL 206
G P E++ + +E ++ V+K LD ET+ + + + +D+G PPL S + + VL
Sbjct: 1790 DGDPLGEFV--ISPVEGVLRVRKDVELDRETIAFYNLTICARDRGMPPLSSTMLVGIRVL 1847
Query: 207 DADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSST-GDHKQL 265
D +D +P + +++ +F+ + A+D D G NA L ++ T G+ ++
Sbjct: 1848 DINDNDPVLLNLPMNITISENSPVSSFV----AHVLASDADSGCNARLTFNITAGNRERA 1903
Query: 266 IVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXX 325
+N TG V + L E P + + DNP+ +A
Sbjct: 1904 FFINATTGIVTVNRPLDRERIPEYKLTISVK--DNPENPRIARRDYDLLLIFLSDENDNH 1961
Query: 326 LQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDR---SFLDKFAINNA 382
FT+ Y V E SP LT+ P + + V+ + + F IN++
Sbjct: 1962 PLFTKSTYQAEVMEN-SPAGTPLTVLNGPILALDADQDIYAVVTYQLLGAQSGLFDINSS 2020
Query: 383 GEVILRRS---LDYETTSNYFYQVMVTD---SISNDTASINISVEDVNEWEPRF 430
V+ RS +D E S ++++ + N TA + I++ D N+ P F
Sbjct: 2021 TGVVTVRSGVIIDREAFSPPILELLLLAEDIGLLNSTAHLLITILDDNDNRPTF 2074
Score = 77.0 bits (181), Expect = 3e-13
Identities = 81/352 (23%), Positives = 144/352 (40%), Gaps = 24/352 (6%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPG-P 152
V V + D+NDN P ++ P+ V E D D+ G + + Y + G P
Sbjct: 881 VFVNLLDLNDNDPTFQNLPFVAEVLEGIPAGVSIYQVVAIDLDE-GLNGLVSYRMPVGMP 939
Query: 153 HSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQN 212
++L N ++V LD E + + +++ D G+P S +TL + VLD +D+
Sbjct: 940 RMDFL--INSSSGVVVTTTELDRERIAEYQLRVVASDAGTPTKSSTSTLTIHVLDVNDET 997
Query: 213 PKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQ-LIVVNKD 271
P F Y + +D + ++ D D+G+NA L Y TG + V
Sbjct: 998 PTFFPAVYNVSVSEDVPREFRVVW----LNCTDNDVGLNAELSYFITGGNVDGKFSVGYR 1053
Query: 272 TGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQK 331
V L E + ++L+A +DN T + F Q
Sbjct: 1054 DAVVRTVVGLDRETTAAYMLILEA--IDNGPVGKRHTGTATVFVTVLDVNDNRPI-FLQS 1110
Query: 332 QYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILR--R 389
Y +V E G +L L + E + + + + + F I+ + +++R R
Sbjct: 1111 SYEASVPEDIPEGHSILQLKATDAD-EGEFGRVWYRILHGNHGNNFRIHVSNGLLMRGPR 1169
Query: 390 SLDYETTSNYFYQVMVTDSISND------TASINISVEDVNEWEPRFRHPQY 435
LD E S++ V++ ++ ++D + + + VED+N+ P F QY
Sbjct: 1170 PLDRERNSSH---VLIVEAYNHDLGPMRSSVRVIVYVEDINDEAPVFTQQQY 1218
Score = 74.1 bits (174), Expect = 2e-12
Identities = 83/355 (23%), Positives = 153/355 (43%), Gaps = 28/355 (7%)
Query: 92 IPVSVRVWDVNDNAPQWE-GAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLP 150
+ V + V D NDN+P+++ + AV + E D D G + + +++
Sbjct: 1407 VKVYITVLDENDNSPRFDFTSDSAVSIPEDCPVGQRVATVKAWDPDA-GSNGQVVFSLAS 1465
Query: 151 GPHSEYLGFENELEPI--IVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDA 208
G + + I + V +PLD E ++++ +++ D+G+PP D LQVT+LD
Sbjct: 1466 GNIAGAFEIVTTNDSIGEVFVARPLDREELDHYILQVVASDRGTPPRKKDHILQVTILDI 1525
Query: 209 DDQNPKFTYEH-YTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIV 267
+D P Y + ++ GT + + A D+D+GIN+ L Y T +K +
Sbjct: 1526 NDNPPVIESPFGYNVSVNENVGGGTAVV----QVRATDRDIGINSVLSYYITEGNKDMAF 1581
Query: 268 -VNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXL 326
+++ +G++ AT+ + + L AT D AT
Sbjct: 1582 RMDRISGEI-ATRPAPPDRERQSFYHLVATVEDEGTPTLSAT---THVYVTIVDENDNAP 1637
Query: 327 QFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESP---LQFYVSDRSFLDKFAIN-NA 382
F Q Y + EG P ++ +L T+ Q + E P + + + + ++ F I+ +
Sbjct: 1638 MFQQPHYEVLLDEG--PDTLNTSLITI-QALDLDEGPNGTVTYAIVAGNIVNTFRIDRHM 1694
Query: 383 GEVILRRSLDYETT-SNYFYQVMVTDSIS------NDTASINISVEDVNEWEPRF 430
G + + LDYE + Y V TD T ++ ++V D+N+ P F
Sbjct: 1695 GVITAAKELDYEISHGRYTLIVTATDQCPILSHRLTSTTTVLVNVNDINDNVPTF 1749
Score = 70.1 bits (164), Expect = 3e-11
Identities = 82/363 (22%), Positives = 148/363 (40%), Gaps = 33/363 (9%)
Query: 96 VRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSE 155
+ + D NDN P + A V + E +D D G + L Y + G
Sbjct: 2062 ITILDDNDNRPTFSPATLTVHLLENCPPGFSVLQVTATDEDS-GLNGELVYRIEAGAQDR 2120
Query: 156 YLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKF 215
+L I V +D E ++ + + D+G+ PL + + + D +D P+F
Sbjct: 2121 FL-IHLVTGVIRVGNATIDREEQESYRLTVVATDRGTVPLSGTAIVTILIDDINDSRPEF 2179
Query: 216 TYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTG-----DHKQLI---- 266
T + + AE GT + I+A D DL N L+Y G D +L+
Sbjct: 2180 LNPIQTVSVLESAEPGTVIAN----ITAIDHDL--NPKLEYHIVGIVAKDDTDRLVPNQE 2233
Query: 267 ---VVNKDTGQVAA----TKQLIAELDPSVTIVLKATQVDNPDR-YALATLXXXXXXXXX 318
VN +TG V ++L+A + +++++ A+ D P+R ++
Sbjct: 2234 DAFAVNINTGSVMVKSPMNRELVATYEVTLSVIDNAS--DLPERSVSVPNAKLTVNVLDV 2291
Query: 319 XXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSD--RSFLDK 376
F Y + EGA+PG+ L+ + V + + + + D +
Sbjct: 2292 NDNTPQFKPFGITYYMERILEGATPGTTLIAVAAVDPDKGL-NGLVTYTLLDLVPPGYVQ 2350
Query: 377 FAINNAGEVILRRSLDYETTSNYFYQVMVTDSISNDTAS---INISVEDVNEWEPRFRHP 433
++AG+VI R++DYE + V +D+ S A+ + + + D+N+ P F P
Sbjct: 2351 LEDSSAGKVIANRTVDYEEVHWLNFTVRASDNGSPPRAAEIPVYLEIVDINDNNPIFDQP 2410
Query: 434 QYE 436
Y+
Sbjct: 2411 SYQ 2413
Score = 66.5 bits (155), Expect = 4e-10
Identities = 83/392 (21%), Positives = 146/392 (37%), Gaps = 17/392 (4%)
Query: 48 VGIVPGSKNLTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQ 107
+ + G +++ R LD E+ I +Y+ V + +PV++ V+D NDN P
Sbjct: 617 ISLYEGYGVISVSRPLDYEQ-ISNGLIYLTVMAMDAGNPPLNSTVPVTIEVFDENDNPPT 675
Query: 108 WEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPII 167
+ Y V V E +D D+ + +++ N I
Sbjct: 676 FSKPAYFVSVVENIMAGATVLFLNATDLDRSREYG--QESIIYSLEGSTQFRINARSGEI 733
Query: 168 VVKKPLDFETVNNFTIKLRVQD--QGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLP 225
LD ET + + + +R D G T+ +T+LD +D +P + Y L
Sbjct: 734 TTTSLLDRETKSEYILIVRAVDGGVGHNQKTGIATVNITLLDINDNHPTWKDAPYYINLV 793
Query: 226 DDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLI--A 283
+ + +TT + A D DLG N L YS +K +N TG++ T ++
Sbjct: 794 EMTPPDSDVTT----VVAVDPDLGENGTLVYSIQPPNK-FYSLNSTTGKIRTTHAMLDRE 848
Query: 284 ELDPSVTIVLKATQVDNPD--RYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGA 341
DP +++ V D R L F + V EG
Sbjct: 849 NPDPHEAELMRKIVVSVTDCGRPPLKATSSATVFVNLLDLNDNDPTFQNLPFVAEVLEGI 908
Query: 342 SPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFY 401
G + + + + +D +++G V+ LD E + Y
Sbjct: 909 PAGVSIYQVVAIDLDEGLNGLVSYRMPVGMPRMDFLINSSSGVVVTTTELDRERIAEYQL 968
Query: 402 QVMVTDS---ISNDTASINISVEDVNEWEPRF 430
+V+ +D+ + T+++ I V DVN+ P F
Sbjct: 969 RVVASDAGTPTKSSTSTLTIHVLDVNDETPTF 1000
Score = 64.1 bits (149), Expect = 2e-09
Identities = 53/222 (23%), Positives = 94/222 (42%), Gaps = 10/222 (4%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVL-PGP 152
V + V DVNDN P ++ Y + E +D D P P++ + Y+++
Sbjct: 552 VRINVLDVNDNVPTFQKDAYVGALRENEPSVTQLVRLRATDEDSP-PNNQITYSIVSASA 610
Query: 153 HSEYLGFE-NELEPIIVVKKPLDFETVNNFTIKLRV--QDQGSPPLYSDTTLQVTVLDAD 209
Y E +I V +PLD+E ++N I L V D G+PPL S + + V D +
Sbjct: 611 FGSYFDISLYEGYGVISVSRPLDYEQISNGLIYLTVMAMDAGNPPLNSTVPVTIEVFDEN 670
Query: 210 DQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVN 269
D P F+ Y + ++ G + ++ G + YS G + +N
Sbjct: 671 DNPPTFSKPAYFVSVVENIMAGATVLFLNATDLDRSREYG-QESIIYSLEGSTQ--FRIN 727
Query: 270 KDTGQVAATKQLIAELDPSVTIVLKATQ--VDNPDRYALATL 309
+G++ T L E ++++A V + + +AT+
Sbjct: 728 ARSGEITTTSLLDRETKSEYILIVRAVDGGVGHNQKTGIATV 769
Score = 62.1 bits (144), Expect = 9e-09
Identities = 90/364 (24%), Positives = 150/364 (41%), Gaps = 28/364 (7%)
Query: 85 TTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSAL 144
T S +++ V DVND P + A Y V VSE +D D G ++ L
Sbjct: 977 TPTKSSTSTLTIHVLDVNDETPTFFPAVYNVSVSEDVPREFRVVWLNCTDND-VGLNAEL 1035
Query: 145 HYAVLPG--PHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGS-PPLYSDT-T 200
Y + G +G+ + + +V LD ET + + L D G ++ T T
Sbjct: 1036 SYFITGGNVDGKFSVGYRDAVVRTVV---GLDRETTAAYMLILEAIDNGPVGKRHTGTAT 1092
Query: 201 LQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSST- 259
+ VTVLD +D P F Y A +P+D EG + + A D D G + Y
Sbjct: 1093 VFVTVLDVNDNRPIFLQSSYEASVPEDIPEGHSIL----QLKATDADEGEFGRVWYRILH 1148
Query: 260 GDHKQLIVVNKDTG-QVAATKQLIAELDPSVTIVLKATQVD-NPDRYALATLXXXXXXXX 317
G+H ++ G + + L E + S ++++A D P R ++ +
Sbjct: 1149 GNHGNNFRIHVSNGLLMRGPRPLDRERNSSHVLIVEAYNHDLGPMRSSVRVIVYVEDIND 1208
Query: 318 XXXXXXXXLQFTQKQYSTT-VSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDK 376
FTQ+QYS + E A G+ ++ + +++ + L Y K
Sbjct: 1209 EAPV------FTQQQYSRLGLRETAGIGTSVIVVQATDRDS--GDGGLVNYRILSGAEGK 1260
Query: 377 FAIN-NAGEVILRRSLDYETTSNYFYQVMVTDS---ISNDTASINISVEDVNEWEPRFRH 432
F I+ + G +I LDYET ++Y V TD + S+ I++ + + +F +
Sbjct: 1261 FEIDESTGLIITVNYLDYETKTSYMMNVSATDQAPPFNQGFCSVYITLLNELDEAVQFSN 1320
Query: 433 PQYE 436
YE
Sbjct: 1321 ASYE 1324
Score = 57.2 bits (132), Expect = 2e-07
Identities = 59/281 (20%), Positives = 123/281 (43%), Gaps = 20/281 (7%)
Query: 166 IIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTAL-L 224
+I V+ +D E + +T+ + V D G P + S + +TVLD +D +P+F + +A+ +
Sbjct: 1375 VITVQGLVDREKGDFYTLTV-VADDGGPKVDSTVKVYITVLDENDNSPRFDFTSDSAVSI 1433
Query: 225 PDDAEEGTFLTTSPGPISAADQDLGINAPLQYS-STGDHK---QLIVVNKDTGQVAATKQ 280
P+D G + T + A D D G N + +S ++G+ +++ N G+V +
Sbjct: 1434 PEDCPVGQRVAT----VKAWDPDAGSNGQVVFSLASGNIAGAFEIVTTNDSIGEVFVARP 1489
Query: 281 LIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEG 340
L E + + A+ P R L + Y+ +V+E
Sbjct: 1490 LDREELDHYILQVVASDRGTPPRKKDHILQVTILDINDNPPVIE----SPFGYNVSVNEN 1545
Query: 341 ASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAINN-AGEVILRRSLDYETTSNY 399
G+ ++ + ++ S L +Y+++ + F ++ +GE+ R + ++
Sbjct: 1546 VGGGTAVVQVRATDRDIGIN-SVLSYYITEGNKDMAFRMDRISGEIATRPAPPDRERQSF 1604
Query: 400 FYQVMVTDSISNDTAS----INISVEDVNEWEPRFRHPQYE 436
++ V + T S + +++ D N+ P F+ P YE
Sbjct: 1605 YHLVATVEDEGTPTLSATTHVYVTIVDENDNAPMFQQPHYE 1645
Score = 56.0 bits (129), Expect = 6e-07
Identities = 74/355 (20%), Positives = 144/355 (40%), Gaps = 30/355 (8%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
V + + + NDN P + Y + + E +D D G + Y P
Sbjct: 451 VKITLINENDNRPIFSQPLYNISLYENVTVGTSVLTVLATDNDA-GTFGEVSYFFSDDP- 508
Query: 154 SEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNP 213
+ + + I+++ + LD+E + FT+ + +D G + +++ VLD +D P
Sbjct: 509 -DRFSLDKDTGLIMLIAR-LDYELIQRFTLTIIARDGGGEE--TTGRVRINVLDVNDNVP 564
Query: 214 KFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQY-----SSTGDHKQLIVV 268
F + Y L ++ T L + A D+D N + Y S+ G + I +
Sbjct: 565 TFQKDAYVGALRENEPSVTQLVR----LRATDEDSPPNNQITYSIVSASAFGSYFD-ISL 619
Query: 269 NKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQF 328
+ G ++ ++ L E + I L +D + +T+ F
Sbjct: 620 YEGYGVISVSRPLDYEQISNGLIYLTVMAMDAGNPPLNSTVPVTIEVFDENDNPPT---F 676
Query: 329 TQKQYSTTVSEGASPGSVLLTL--TTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEV 385
++ Y +V E G+ +L L T + ++ E+ + + + + + +F IN +GE+
Sbjct: 677 SKPAYFVSVVENIMAGATVLFLNATDLDRSREYGQESIIYSLEGST---QFRINARSGEI 733
Query: 386 ILRRSLDYETTSNYFYQVMVTD-----SISNDTASINISVEDVNEWEPRFRHPQY 435
LD ET S Y V D + A++NI++ D+N+ P ++ Y
Sbjct: 734 TTTSLLDRETKSEYILIVRAVDGGVGHNQKTGIATVNITLLDINDNHPTWKDAPY 788
Score = 54.0 bits (124), Expect = 2e-06
Identities = 66/247 (26%), Positives = 110/247 (44%), Gaps = 29/247 (11%)
Query: 50 IVPGSKNLTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQW- 108
I P S + + LDRE + S + V D + + P+ V + D++DN P +
Sbjct: 2671 IDPISGLIQTAQRLDRESQAVYSLILV--ASDLGQPVPYETMQPLQVALEDIDDNEPLFV 2728
Query: 109 ---EGAPY--AVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENEL 163
+G+P + V E + GP++ ++Y + G +E F +
Sbjct: 2729 RPPKGSPQYQLLTVPEHSPRGTLVGNVTGAVDADEGPNAIVYYFIAAG--NEEKNFHLQP 2786
Query: 164 EPIIVVKKPLDFE--TVNNFTIKLRVQDQGSPP--------LYSDTTLQ---VTVLDADD 210
+ ++V + LD E + +F +K +PP L +D TLQ V + D +D
Sbjct: 2787 DGCLLVLRDLDREREAIFSFIVKASSNRSWTPPRGPSPTLDLVADLTLQEVRVVLEDIND 2846
Query: 211 QNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDH--KQLIVV 268
Q P+FT YTA + DA+ G+ L + A D D+G N+ + YS H + L
Sbjct: 2847 QPPRFTKAEYTAGVATDAKVGSELI----QVLALDADIGNNSLVFYSILAIHYFRALAND 2902
Query: 269 NKDTGQV 275
++D GQV
Sbjct: 2903 SEDVGQV 2909
Score = 51.2 bits (117), Expect = 2e-05
Identities = 111/522 (21%), Positives = 189/522 (36%), Gaps = 37/522 (7%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRA---LDREE 67
+ ED P G I L + G + R+ N L+R LDRE
Sbjct: 1116 VPEDIPEGHSILQLKATDADEGEFGRVWYRILHGNHGNNFRIHVSNGLLMRGPRPLDRER 1175
Query: 68 KIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYA-VRVSETXXXXXX 126
S+V + V + V V V D+ND AP + Y+ + + ET
Sbjct: 1176 N--SSHVLI-VEAYNHDLGPMRSSVRVIVYVEDINDEAPVFTQQQYSRLGLRETAGIGTS 1232
Query: 127 XXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFE-NELEPIIVVKKPLDFETVNNFTIKL 185
+DRD G ++Y +L G + FE +E +I+ LD+ET ++ + +
Sbjct: 1233 VIVVQATDRDS-GDGGLVNYRILSGAEGK---FEIDESTGLIITVNYLDYETKTSYMMNV 1288
Query: 186 RVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGT-FLTTSPGPISAA 244
DQ P ++ +T+L+ D+ +F+ Y A + ++ GT + I
Sbjct: 1289 SATDQAPPFNQGFCSVYITLLNELDEAVQFSNASYEAAILENLALGTEIVRVQAYSIDNL 1348
Query: 245 DQ-DLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDR 303
+Q NA Y+ST K L ++ TG + T Q + + + L D +
Sbjct: 1349 NQITYRFNA---YTST-QAKALFKIDAITGVI--TVQGLVDREKGDFYTLTVVADDGGPK 1402
Query: 304 YALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESP 363
+ + FT + ++ E G + T+ +
Sbjct: 1403 --VDSTVKVYITVLDENDNSPRFDFTSDS-AVSIPEDCPVGQRVATVKAWDPDAG-SNGQ 1458
Query: 364 LQFYVSDRSFLDKFAI----NNAGEVILRRSLDYETTSNYFYQVMVTDSISNDTAS---I 416
+ F ++ + F I ++ GEV + R LD E +Y QV+ +D + +
Sbjct: 1459 VVFSLASGNIAGAFEIVTTNDSIGEVFVARPLDREELDHYILQVVASDRGTPPRKKDHIL 1518
Query: 417 NISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAHD-GDAGTLALSLA-G 474
+++ D+N+ P P F D G L+ + G
Sbjct: 1519 QVTILDINDNPPVIESP---FGYNVSVNENVGGGTAVVQVRATDRDIGINSVLSYYITEG 1575
Query: 475 QHARMFYIN-ASGDLFLREEAIGNLNSSSLHLVATAIDSGIP 515
F ++ SG++ R S HLVAT D G P
Sbjct: 1576 NKDMAFRMDRISGEIATRPAPPDRERQSFYHLVATVEDEGTP 1617
Score = 44.8 bits (101), Expect = 0.001
Identities = 36/111 (32%), Positives = 50/111 (45%), Gaps = 7/111 (6%)
Query: 328 FTQKQYST--TVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGE 384
FT + T +SE GS + L + + PL F VS FA+ + G
Sbjct: 31 FTNHFFDTYLLISEDTPVGSSVTQLLAQDMDND----PLVFGVSGEEASRFFAVEPDTGV 86
Query: 385 VILRRSLDYETTSNYFYQVMVTDSISNDTASINISVEDVNEWEPRFRHPQY 435
V LR+ LD ET S + + V+D T +NI V DVN+ P F + Y
Sbjct: 87 VWLRQPLDRETKSEFTVEFSVSDHQGVITRKVNIQVGDVNDNAPTFHNQPY 137
>AF312024-1|AAG48303.1| 3354|Homo sapiens cadherin related 23 protein.
Length = 3354
Score = 99.5 bits (237), Expect = 5e-20
Identities = 96/369 (26%), Positives = 156/369 (42%), Gaps = 28/369 (7%)
Query: 80 CDRRRTTDP-SFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQP 138
C R R P S + V +RV D+NDN P P + +SE SD D
Sbjct: 1822 CARDRGMPPLSSTMLVGIRVLDINDNDPVLLNLPMNITISENSPVSSFVAHVLASDADS- 1880
Query: 139 GPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYS- 197
G ++ L + + G + E F N I+ V +PLD E + + + + V+D P +
Sbjct: 1881 GCNARLTFNITAG-NRERAFFINATTGIVTVNRPLDRERIPEYKLTISVKDNPENPRIAR 1939
Query: 198 -DTTLQVTVL-DADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQ 255
D L + L D +D +P FT Y A + +++ GT LT GPI A D D I A +
Sbjct: 1940 RDYDLLLIFLSDENDNHPLFTKSTYQAEVMENSPAGTPLTVLNGPILALDADQDIYAVVT 1999
Query: 256 YSSTGDHKQLIVVNKDTGQVAATKQLIAELD----PSVTIVLKATQVD--NPDRYALATL 309
Y G L +N TG V +I + + P + ++L A + N + L T+
Sbjct: 2000 YQLLGAQSGLFDINSSTGVVTVRSGVIIDREAFSPPILELLLLAEDIGLLNSTAHLLITI 2059
Query: 310 XXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVS 369
F+ + + E PG +L +T +++ + Y
Sbjct: 2060 LDDNDNRPT---------FSPATLTVHLLENCPPGFSVLQVTATDEDSGLNGELV--YRI 2108
Query: 370 DRSFLDKFAINNAGEVIL--RRSLDYETTSNYFYQVMVTDSIS---NDTASINISVEDVN 424
+ D+F I+ VI ++D E +Y V+ TD + + TA + I ++D+N
Sbjct: 2109 EAGAQDRFLIHLVTGVIRVGNATIDREEQESYRLTVVATDRGTVPLSGTAIVTILIDDIN 2168
Query: 425 EWEPRFRHP 433
+ P F +P
Sbjct: 2169 DSRPEFLNP 2177
Score = 94.3 bits (224), Expect = 2e-18
Identities = 102/417 (24%), Positives = 179/417 (42%), Gaps = 26/417 (6%)
Query: 28 GDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEKIGPSNVYVNVRCDRRRTTD 87
G ++D D + QE AV I GS ++++ E + V ++V + +
Sbjct: 2213 GIVAKDDTDRLVPNQEDAFAVNINTGS---VMVKSPMNRELVATYEVTLSVIDNASDLPE 2269
Query: 88 PSFVIP---VSVRVWDVNDNAPQWE--GAPYAV-RVSETXXXXXXXXXXXXSDRDQPGPH 141
S +P ++V V DVNDN PQ++ G Y + R+ E D D+ G +
Sbjct: 2270 RSVSVPNAKLTVNVLDVNDNTPQFKPFGITYYMERILEGATPGTTLIAVAAVDPDK-GLN 2328
Query: 142 SALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTL 201
+ Y +L Y+ E+ ++ + +D+E V+ +R D GSPP ++ +
Sbjct: 2329 GLVTYTLLDLVPPGYVQLEDSSAGKVIANRTVDYEEVHWLNFTVRASDNGSPPRAAEIPV 2388
Query: 202 QVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGD 261
+ ++D +D NP F Y + +D GT + T ++A D D G A ++Y S GD
Sbjct: 2389 YLEIVDINDNNPIFDQPSYQEAVFEDVPVGTIILT----VTATDADSGNFALIEY-SLGD 2443
Query: 262 HKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNP-DRYALATLXXXXXXXXXXX 320
+ +N TG + L + + +L A DNP D +
Sbjct: 2444 GESKFAINPTTGDIYVLSSL--DREKKDHYILTALAKDNPGDVASNRRENSVQVVIQVLD 2501
Query: 321 XXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAIN 380
QF++ Q+ST+V E G+ ++T+ Q+ E L Y + ++ F ++
Sbjct: 2502 VNDCRPQFSKPQFSTSVYENEPAGTSVITMMATDQD-EGPNGELT-YSLEGPGVEAFHVD 2559
Query: 381 -NAGEVILRRSLDYETTSNYFYQVMVTDSISN---DTASINISVEDVNEWEPRFRHP 433
++G V +R L ++ + V+ TD T + + V DVN+ P F P
Sbjct: 2560 MDSGLVTTQRPL--QSYEKFSLTVVATDGGEPPLWGTTMLLVEVIDVNDNRPVFVRP 2614
Score = 92.7 bits (220), Expect = 5e-18
Identities = 101/454 (22%), Positives = 197/454 (43%), Gaps = 42/454 (9%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEK-- 68
+ ED P+G+II T++ S + I L + + I P + ++ +L +LDRE+K
Sbjct: 2411 VFEDVPVGTIILTVTATDADSGNFALIEYSLGDGESKFAINPTTGDIYVLSSLDREKKDH 2470
Query: 69 -----IGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXX 123
+ N +V +RR + + V ++V DVND PQ+ ++ V E
Sbjct: 2471 YILTALAKDNP-GDVASNRRENS-----VQVVIQVLDVNDCRPQFSKPQFSTSVYENEPA 2524
Query: 124 XXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTI 183
+D+D+ GP+ L Y+ L GP E + + ++ ++PL ++ F++
Sbjct: 2525 GTSVITMMATDQDE-GPNGELTYS-LEGPGVEAFHVDMD-SGLVTTQRPL--QSYEKFSL 2579
Query: 184 KLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISA 243
+ D G PPL+ T L V V+D +D P F +L E L ++ + A
Sbjct: 2580 TVVATDGGEPPLWGTTMLLVEVIDVNDNRPVFVRPPNGTIL--HIREEIPLRSNVYEVYA 2637
Query: 244 ADQDLGINAPLQYS--STGDHK--QLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVD 299
D+D G+N ++YS T ++ + +++ +G + ++L E +++L A+ +
Sbjct: 2638 TDKDEGLNGAVRYSFLKTAGNRDWEFFIIDPISGLIQTAQRLDRESQAVYSLILVASDLG 2697
Query: 300 NPDRY-ALATLXXXXXXXXXXXXXXXXLQFTQKQYS-TTVSEGASPGSVLLTLTTVPQNT 357
P Y + L QY TV E + G+++ +T
Sbjct: 2698 QPVPYETMQPLQVALEDIDDNEPLFVRPPKGSPQYQLLTVPEHSPRGTLVGNVTGAVDAD 2757
Query: 358 EFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVT----------- 406
E + + ++++ + F + G +++ R LD E + + + V +
Sbjct: 2758 EGPNAIVYYFIAAGNEEKNFHLQPDGCLLVLRDLDREREAIFSFIVKASSNRSWTPPRGP 2817
Query: 407 ----DSISNDT-ASINISVEDVNEWEPRFRHPQY 435
D +++ T + + +ED+N+ PRF +Y
Sbjct: 2818 SPTLDLVADLTLQEVRVVLEDINDQPPRFTKAEY 2851
Score = 92.3 bits (219), Expect = 7e-18
Identities = 102/440 (23%), Positives = 179/440 (40%), Gaps = 31/440 (7%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEKIG 70
ISEDTP+GS + L D D + +E + P + + L + LDRE K
Sbjct: 42 ISEDTPVGSSVTQLLAQ-DMDNDPLVFGVSGEEASRFFAVEPDTGVVWLRQPLDRETK-- 98
Query: 71 PSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXX 130
S V + V+++V DVNDNAP + PY+VR+ E
Sbjct: 99 -SEFTVEFSVSDHQGV---ITRKVNIQVGDVNDNAPTFHNQPYSVRIPENTPVGTPIFIV 154
Query: 131 XXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQ 190
+D D S L+ P S++ ++ I+ V + LD+ET + + + DQ
Sbjct: 155 NATDPDLGAGGSVLYSF---QPPSQFFAIDS-ARGIVTVIRELDYETTQAYQLTVNATDQ 210
Query: 191 G-SPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLG 249
+ PL + L + + D D +P F Y+ + + + GT + I+A DQD G
Sbjct: 211 DKTRPLSTLANLAIIITDVQDMDPIFINLPYSTNIYEHSPPGTTVRI----ITAIDQDKG 266
Query: 250 INAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAE---LDPSVTIVLKATQVDNPDRYA 305
+ Y+ +G+ + ++ +G + L E + +K T++ N DR
Sbjct: 267 RPRGIGYTIVSGNTNSIFALDYISGVLTLNGLLDRENPLYSHGFILTVKGTEL-NDDRTP 325
Query: 306 LATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVL-LTLTTVPQNTEF-RESP 363
+F +YS ++E A G L L + V ++ S
Sbjct: 326 SDATVTTTFNILVIDINDNAPEFNSSEYSVAITELAQVGFALPLFIQVVDKDENLGLNSM 385
Query: 364 LQFYV----SDRSFLDKFAINNAGEVILRRS--LDYETTSNYFYQVMVTDSISNDT--AS 415
+ Y+ S + ++ ++ +R + LDYET Y + + +S+ + A
Sbjct: 386 FEVYLVGNNSHHFIISPTSVQGKADIRIRVAIPLDYETVDRYDFDLFANESVPDHVGYAK 445
Query: 416 INISVEDVNEWEPRFRHPQY 435
+ I++ + N+ P F P Y
Sbjct: 446 VKITLINENDNRPIFSQPLY 465
Score = 84.2 bits (199), Expect = 2e-15
Identities = 105/449 (23%), Positives = 173/449 (38%), Gaps = 31/449 (6%)
Query: 91 VIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLP 150
+ V++ + D+NDN P W+ APY + + E D D G + L Y++ P
Sbjct: 761 IATVNITLLDINDNHPTWKDAPYYINLVEMTPPDSDVTTVVAVDPDL-GENGTLVYSIQP 819
Query: 151 GPHSEY-----LGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPL--YSDTTLQV 203
P+ Y G ++ + P E I + V D G PPL S T+ V
Sbjct: 820 -PNKFYSLNSTTGKIRTTHAMLDRENPDPHEAELMRKIVVSVTDCGRPPLKATSSATVFV 878
Query: 204 TVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQY-SSTGDH 262
+LD +D +P F + A + EG S + A D D G+N + Y G
Sbjct: 879 NLLDLNDNDPTFQNLPFVA----EVLEGIPAGVSIYQVVAIDLDEGLNGLVSYRMPVGMP 934
Query: 263 KQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXX 322
+ ++N +G V T +L E + + A+ P + + +TL
Sbjct: 935 RMDFLINSSSGVVVTTTELDRERIAEYQLRVVASDAGTPTKSSTSTLTIHVLDVNDETPT 994
Query: 323 XXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAINNA 382
F Y+ +VSE P + N + L ++++ + KF++
Sbjct: 995 -----FFPAVYNVSVSEDV-PREFRVVWLNCTDNDVGLNAELSYFITGGNVDGKFSVGYR 1048
Query: 383 GEVILR-RSLDYETTSNYFYQVMVTDS-----ISNDTASINISVEDVNEWEPRFRHPQYE 436
V+ LD ETT+ Y + D+ TA++ ++V DVN+ P F YE
Sbjct: 1049 DAVVRTVVGLDRETTAAYMLILEAIDNGPVGKRHTGTATVFVTVLDVNDNRPIFLQSSYE 1108
Query: 437 FEXXXXXXXXXXXXXXXXXXXXVAHDGDAGTLALS-LAGQHARMFYINASGDLFLR-EEA 494
A +G+ G + L G H F I+ S L +R
Sbjct: 1109 ---ASVPEDIPEGHSILQLKATDADEGEFGRVWYRILHGNHGNNFRIHVSNGLLMRGPRP 1165
Query: 495 IGNLNSSSLHLVATAIDSGIPPRQTSVPV 523
+ +SS L+ A + + P ++SV V
Sbjct: 1166 LDRERNSSHVLIVEAYNHDLGPMRSSVRV 1194
Score = 82.6 bits (195), Expect = 6e-15
Identities = 104/480 (21%), Positives = 181/480 (37%), Gaps = 33/480 (6%)
Query: 57 LTLLRALDREEKIGPSNVYVNVRC----DRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAP 112
LTL LDRE + + V+ D R +D + ++ V D+NDNAP++ +
Sbjct: 293 LTLNGLLDRENPLYSHGFILTVKGTELNDDRTPSDATVTTTFNILVIDINDNAPEFNSSE 352
Query: 113 YAVRVSETXXXXXXX-XXXXXSDRDQPGPHSALHYAVLPGPHSEYL-----GFENELEPI 166
Y+V ++E D+D+ +++ L G +S + + + +
Sbjct: 353 YSVAITELAQVGFALPLFIQVVDKDENLGLNSMFEVYLVGNNSHHFIISPTSVQGKADIR 412
Query: 167 IVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPD 226
I V PLD+ETV+ + L ++ P +++T+++ +D P F+ Y L +
Sbjct: 413 IRVAIPLDYETVDRYDFDL-FANESVPDHVGYAKVKITLINENDNRPIFSQPLYNISLYE 471
Query: 227 DAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLIAELD 286
+ GT + T + A D D G + Y + D + + +KDTG + +L EL
Sbjct: 472 NVTVGTSVLT----VLATDNDAGTFGEVSYFFSDDPDRFSL-DKDTGLIMLIARLDYELI 526
Query: 287 PSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSV 346
T+ + A + + F + Y + E +
Sbjct: 527 QRFTLTIIARDGGGEETTGRVRINVLDVNDNVPT-------FQKDAYVGALRENEPSVTQ 579
Query: 347 LLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAIN---NAGEVILRRSLDYETTSN--YFY 401
L+ L +++ VS +F F I+ G + + R LDYE SN +
Sbjct: 580 LVRLRATDEDSPPNNQITYSIVSASAFGSYFDISLYEGYGVISVSRPLDYEQISNGLIYL 639
Query: 402 QVMVTDSIS---NDTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXX 458
VM D+ + N T + I V D N+ P F P Y
Sbjct: 640 TVMAMDAGNPPLNSTVPVTIEVFDENDNPPTFSKPAYFVSVVENIMAGATVLFLNATDLD 699
Query: 459 VAHDGDAGTLALSLAGQHARMFYINASGDLFLREEAIGNLNSSSLHLVATAIDSGIPPRQ 518
+ + ++ SL G + F INA + S L+ A+D G+ Q
Sbjct: 700 RSREYGQESIIYSLEG--STQFRINARSGEITTTSLLDRETKSEYILIVRAVDGGVGHNQ 757
Score = 81.0 bits (191), Expect = 2e-14
Identities = 113/480 (23%), Positives = 186/480 (38%), Gaps = 47/480 (9%)
Query: 63 LDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXX 122
+DREE+ + + V R T S V++ + D+ND+ P++ V V E+
Sbjct: 2132 IDREEQ---ESYRLTVVATDRGTVPLSGTAIVTILIDDINDSRPEFLNPIQTVSVLESAE 2188
Query: 123 XXXXXXXXXXSDRDQPGPHSALHYAVLPG--------PHSEYLGFENELEPIIVVKKPLD 174
D D P H + P+ E N ++VK P++
Sbjct: 2189 PGTVIANITAIDHDL-NPKLEYHIVGIVAKDDTDRLVPNQEDAFAVNINTGSVMVKSPMN 2247
Query: 175 FETVNNFTIKLRVQDQGSP-PLYS----DTTLQVTVLDADDQNPKFT---YEHYTALLPD 226
E V + + L V D S P S + L V VLD +D P+F +Y + +
Sbjct: 2248 RELVATYEVTLSVIDNASDLPERSVSVPNAKLTVNVLDVNDNTPQFKPFGITYYMERILE 2307
Query: 227 DAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDT--GQVAATKQLIAE 284
A GT L ++A D D G+N + Y+ V +D+ G+V A + + E
Sbjct: 2308 GATPGTTLIA----VAAVDPDKGLNGLVTYTLLDLVPPGYVQLEDSSAGKVIANRTVDYE 2363
Query: 285 LDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPG 344
+ ++A+ +P R A + F Q Y V E G
Sbjct: 2364 EVHWLNFTVRASDNGSPPRAAEIPVYLEIVDINDNNPI-----FDQPSYQEAVFEDVPVG 2418
Query: 345 SVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQV 403
+++LT+T ++ + +++ + D KFAIN G++ + SLD E +Y
Sbjct: 2419 TIILTVTATDADSG-NFALIEYSLGDGE--SKFAINPTTGDIYVLSSLDREKKDHYILTA 2475
Query: 404 MVTDS----ISN---DTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXX 456
+ D+ SN ++ + I V DVN+ P+F PQ+
Sbjct: 2476 LAKDNPGDVASNRRENSVQVVIQVLDVNDCRPQFSKPQFSTSVYENEPAGTSVITMMATD 2535
Query: 457 XXVAHDGDAGTLALSLAGQHARMFYINASGDLFLREEAIGNLNSSSLHLVATAIDSGIPP 516
+G G L SL G F+++ L + + + SL +VAT D G PP
Sbjct: 2536 QD---EGPNGELTYSLEGPGVEAFHVDMDSGLVTTQRPLQSYEKFSLTVVAT--DGGEPP 2590
Score = 78.6 bits (185), Expect = 9e-14
Identities = 88/354 (24%), Positives = 153/354 (43%), Gaps = 31/354 (8%)
Query: 94 VSVRVWDVNDNAP----QWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVL 149
V V V D+NDN P +EG P+ V + DRD GP+ + Y+++
Sbjct: 1730 VLVNVNDINDNVPTFPRDYEG-PFEVTEGQPGPRVWTFLAH---DRDS-GPNGQVEYSIM 1784
Query: 150 PG-PHSEYLGFENELEPIIVVKKP--LDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVL 206
G P E++ + +E ++ V+K LD ET+ + + + +D+G PPL S + + VL
Sbjct: 1785 DGDPLGEFV--ISPVEGVLRVRKDVELDRETIAFYNLTICARDRGMPPLSSTMLVGIRVL 1842
Query: 207 DADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSST-GDHKQL 265
D +D +P + +++ +F+ + A+D D G NA L ++ T G+ ++
Sbjct: 1843 DINDNDPVLLNLPMNITISENSPVSSFV----AHVLASDADSGCNARLTFNITAGNRERA 1898
Query: 266 IVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXX 325
+N TG V + L E P + + DNP+ +A
Sbjct: 1899 FFINATTGIVTVNRPLDRERIPEYKLTISVK--DNPENPRIARRDYDLLLIFLSDENDNH 1956
Query: 326 LQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDR---SFLDKFAINNA 382
FT+ Y V E SP LT+ P + + V+ + + F IN++
Sbjct: 1957 PLFTKSTYQAEVMEN-SPAGTPLTVLNGPILALDADQDIYAVVTYQLLGAQSGLFDINSS 2015
Query: 383 GEVILRRS---LDYETTSNYFYQVMVTD---SISNDTASINISVEDVNEWEPRF 430
V+ RS +D E S ++++ + N TA + I++ D N+ P F
Sbjct: 2016 TGVVTVRSGVIIDREAFSPPILELLLLAEDIGLLNSTAHLLITILDDNDNRPTF 2069
Score = 77.0 bits (181), Expect = 3e-13
Identities = 81/352 (23%), Positives = 144/352 (40%), Gaps = 24/352 (6%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPG-P 152
V V + D+NDN P ++ P+ V E D D+ G + + Y + G P
Sbjct: 876 VFVNLLDLNDNDPTFQNLPFVAEVLEGIPAGVSIYQVVAIDLDE-GLNGLVSYRMPVGMP 934
Query: 153 HSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQN 212
++L N ++V LD E + + +++ D G+P S +TL + VLD +D+
Sbjct: 935 RMDFL--INSSSGVVVTTTELDRERIAEYQLRVVASDAGTPTKSSTSTLTIHVLDVNDET 992
Query: 213 PKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQ-LIVVNKD 271
P F Y + +D + ++ D D+G+NA L Y TG + V
Sbjct: 993 PTFFPAVYNVSVSEDVPREFRVVW----LNCTDNDVGLNAELSYFITGGNVDGKFSVGYR 1048
Query: 272 TGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQK 331
V L E + ++L+A +DN T + F Q
Sbjct: 1049 DAVVRTVVGLDRETTAAYMLILEA--IDNGPVGKRHTGTATVFVTVLDVNDNRPI-FLQS 1105
Query: 332 QYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILR--R 389
Y +V E G +L L + E + + + + + F I+ + +++R R
Sbjct: 1106 SYEASVPEDIPEGHSILQLKATDAD-EGEFGRVWYRILHGNHGNNFRIHVSNGLLMRGPR 1164
Query: 390 SLDYETTSNYFYQVMVTDSISND------TASINISVEDVNEWEPRFRHPQY 435
LD E S++ V++ ++ ++D + + + VED+N+ P F QY
Sbjct: 1165 PLDRERNSSH---VLIVEAYNHDLGPMRSSVRVIVYVEDINDEAPVFTQQQY 1213
Score = 74.1 bits (174), Expect = 2e-12
Identities = 83/355 (23%), Positives = 153/355 (43%), Gaps = 28/355 (7%)
Query: 92 IPVSVRVWDVNDNAPQWE-GAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLP 150
+ V + V D NDN+P+++ + AV + E D D G + + +++
Sbjct: 1402 VKVYITVLDENDNSPRFDFTSDSAVSIPEDCPVGQRVATVKAWDPDA-GSNGQVVFSLAS 1460
Query: 151 GPHSEYLGFENELEPI--IVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDA 208
G + + I + V +PLD E ++++ +++ D+G+PP D LQVT+LD
Sbjct: 1461 GNIAGAFEIVTTNDSIGEVFVARPLDREELDHYILQVVASDRGTPPRKKDHILQVTILDI 1520
Query: 209 DDQNPKFTYEH-YTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIV 267
+D P Y + ++ GT + + A D+D+GIN+ L Y T +K +
Sbjct: 1521 NDNPPVIESPFGYNVSVNENVGGGTAVV----QVRATDRDIGINSVLSYYITEGNKDMTF 1576
Query: 268 -VNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXL 326
+++ +G++ AT+ + + L AT D AT
Sbjct: 1577 RMDRISGEI-ATRPAPPDRERQSFYHLVATVEDEGTPTLSAT---THVYVTIVDENDNAP 1632
Query: 327 QFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESP---LQFYVSDRSFLDKFAIN-NA 382
F Q Y + EG P ++ +L T+ Q + E P + + + + ++ F I+ +
Sbjct: 1633 MFQQPHYEVLLDEG--PDTLNTSLITI-QALDLDEGPNGTVTYAIVAGNIVNTFRIDRHM 1689
Query: 383 GEVILRRSLDYETT-SNYFYQVMVTDSIS------NDTASINISVEDVNEWEPRF 430
G + + LDYE + Y V TD T ++ ++V D+N+ P F
Sbjct: 1690 GVITAAKELDYEISHGRYTLIVTATDQCPILSHRLTSTTTVLVNVNDINDNVPTF 1744
Score = 70.1 bits (164), Expect = 3e-11
Identities = 82/363 (22%), Positives = 148/363 (40%), Gaps = 33/363 (9%)
Query: 96 VRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSE 155
+ + D NDN P + A V + E +D D G + L Y + G
Sbjct: 2057 ITILDDNDNRPTFSPATLTVHLLENCPPGFSVLQVTATDEDS-GLNGELVYRIEAGAQDR 2115
Query: 156 YLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKF 215
+L I V +D E ++ + + D+G+ PL + + + D +D P+F
Sbjct: 2116 FL-IHLVTGVIRVGNATIDREEQESYRLTVVATDRGTVPLSGTAIVTILIDDINDSRPEF 2174
Query: 216 TYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTG-----DHKQLI---- 266
T + + AE GT + I+A D DL N L+Y G D +L+
Sbjct: 2175 LNPIQTVSVLESAEPGTVIAN----ITAIDHDL--NPKLEYHIVGIVAKDDTDRLVPNQE 2228
Query: 267 ---VVNKDTGQVAA----TKQLIAELDPSVTIVLKATQVDNPDR-YALATLXXXXXXXXX 318
VN +TG V ++L+A + +++++ A+ D P+R ++
Sbjct: 2229 DAFAVNINTGSVMVKSPMNRELVATYEVTLSVIDNAS--DLPERSVSVPNAKLTVNVLDV 2286
Query: 319 XXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSD--RSFLDK 376
F Y + EGA+PG+ L+ + V + + + + D +
Sbjct: 2287 NDNTPQFKPFGITYYMERILEGATPGTTLIAVAAVDPDKGL-NGLVTYTLLDLVPPGYVQ 2345
Query: 377 FAINNAGEVILRRSLDYETTSNYFYQVMVTDSISNDTAS---INISVEDVNEWEPRFRHP 433
++AG+VI R++DYE + V +D+ S A+ + + + D+N+ P F P
Sbjct: 2346 LEDSSAGKVIANRTVDYEEVHWLNFTVRASDNGSPPRAAEIPVYLEIVDINDNNPIFDQP 2405
Query: 434 QYE 436
Y+
Sbjct: 2406 SYQ 2408
Score = 66.5 bits (155), Expect = 4e-10
Identities = 83/392 (21%), Positives = 146/392 (37%), Gaps = 17/392 (4%)
Query: 48 VGIVPGSKNLTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQ 107
+ + G +++ R LD E+ I +Y+ V + +PV++ V+D NDN P
Sbjct: 612 ISLYEGYGVISVSRPLDYEQ-ISNGLIYLTVMAMDAGNPPLNSTVPVTIEVFDENDNPPT 670
Query: 108 WEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPII 167
+ Y V V E +D D+ + +++ N I
Sbjct: 671 FSKPAYFVSVVENIMAGATVLFLNATDLDRSREYG--QESIIYSLEGSTQFRINARSGEI 728
Query: 168 VVKKPLDFETVNNFTIKLRVQD--QGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLP 225
LD ET + + + +R D G T+ +T+LD +D +P + Y L
Sbjct: 729 TTTSLLDRETKSEYILIVRAVDGGVGHNQKTGIATVNITLLDINDNHPTWKDAPYYINLV 788
Query: 226 DDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLI--A 283
+ + +TT + A D DLG N L YS +K +N TG++ T ++
Sbjct: 789 EMTPPDSDVTT----VVAVDPDLGENGTLVYSIQPPNK-FYSLNSTTGKIRTTHAMLDRE 843
Query: 284 ELDPSVTIVLKATQVDNPD--RYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGA 341
DP +++ V D R L F + V EG
Sbjct: 844 NPDPHEAELMRKIVVSVTDCGRPPLKATSSATVFVNLLDLNDNDPTFQNLPFVAEVLEGI 903
Query: 342 SPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFY 401
G + + + + +D +++G V+ LD E + Y
Sbjct: 904 PAGVSIYQVVAIDLDEGLNGLVSYRMPVGMPRMDFLINSSSGVVVTTTELDRERIAEYQL 963
Query: 402 QVMVTDS---ISNDTASINISVEDVNEWEPRF 430
+V+ +D+ + T+++ I V DVN+ P F
Sbjct: 964 RVVASDAGTPTKSSTSTLTIHVLDVNDETPTF 995
Score = 64.1 bits (149), Expect = 2e-09
Identities = 53/222 (23%), Positives = 94/222 (42%), Gaps = 10/222 (4%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVL-PGP 152
V + V DVNDN P ++ Y + E +D D P P++ + Y+++
Sbjct: 547 VRINVLDVNDNVPTFQKDAYVGALRENEPSVTQLVRLRATDEDSP-PNNQITYSIVSASA 605
Query: 153 HSEYLGFE-NELEPIIVVKKPLDFETVNNFTIKLRV--QDQGSPPLYSDTTLQVTVLDAD 209
Y E +I V +PLD+E ++N I L V D G+PPL S + + V D +
Sbjct: 606 FGSYFDISLYEGYGVISVSRPLDYEQISNGLIYLTVMAMDAGNPPLNSTVPVTIEVFDEN 665
Query: 210 DQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVN 269
D P F+ Y + ++ G + ++ G + YS G + +N
Sbjct: 666 DNPPTFSKPAYFVSVVENIMAGATVLFLNATDLDRSREYG-QESIIYSLEGSTQ--FRIN 722
Query: 270 KDTGQVAATKQLIAELDPSVTIVLKATQ--VDNPDRYALATL 309
+G++ T L E ++++A V + + +AT+
Sbjct: 723 ARSGEITTTSLLDRETKSEYILIVRAVDGGVGHNQKTGIATV 764
Score = 62.1 bits (144), Expect = 9e-09
Identities = 90/364 (24%), Positives = 150/364 (41%), Gaps = 28/364 (7%)
Query: 85 TTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSAL 144
T S +++ V DVND P + A Y V VSE +D D G ++ L
Sbjct: 972 TPTKSSTSTLTIHVLDVNDETPTFFPAVYNVSVSEDVPREFRVVWLNCTDND-VGLNAEL 1030
Query: 145 HYAVLPG--PHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGS-PPLYSDT-T 200
Y + G +G+ + + +V LD ET + + L D G ++ T T
Sbjct: 1031 SYFITGGNVDGKFSVGYRDAVVRTVV---GLDRETTAAYMLILEAIDNGPVGKRHTGTAT 1087
Query: 201 LQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSST- 259
+ VTVLD +D P F Y A +P+D EG + + A D D G + Y
Sbjct: 1088 VFVTVLDVNDNRPIFLQSSYEASVPEDIPEGHSIL----QLKATDADEGEFGRVWYRILH 1143
Query: 260 GDHKQLIVVNKDTG-QVAATKQLIAELDPSVTIVLKATQVD-NPDRYALATLXXXXXXXX 317
G+H ++ G + + L E + S ++++A D P R ++ +
Sbjct: 1144 GNHGNNFRIHVSNGLLMRGPRPLDRERNSSHVLIVEAYNHDLGPMRSSVRVIVYVEDIND 1203
Query: 318 XXXXXXXXLQFTQKQYSTT-VSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDK 376
FTQ+QYS + E A G+ ++ + +++ + L Y K
Sbjct: 1204 EAPV------FTQQQYSRLGLRETAGIGTSVIVVQATDRDS--GDGGLVNYRILSGAEGK 1255
Query: 377 FAIN-NAGEVILRRSLDYETTSNYFYQVMVTDS---ISNDTASINISVEDVNEWEPRFRH 432
F I+ + G +I LDYET ++Y V TD + S+ I++ + + +F +
Sbjct: 1256 FEIDESTGLIITVNYLDYETKTSYMMNVSATDQAPPFNQGFCSVYITLLNELDEAVQFSN 1315
Query: 433 PQYE 436
YE
Sbjct: 1316 ASYE 1319
Score = 57.2 bits (132), Expect = 2e-07
Identities = 63/281 (22%), Positives = 123/281 (43%), Gaps = 20/281 (7%)
Query: 166 IIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTAL-L 224
+I V+ +D E + +T+ + V D G P + S + +TVLD +D +P+F + +A+ +
Sbjct: 1370 VITVQGLVDREKGDFYTLTV-VADDGGPKVDSTVKVYITVLDENDNSPRFDFTSDSAVSI 1428
Query: 225 PDDAEEGTFLTTSPGPISAADQDLGINAPLQYS-STGDHK---QLIVVNKDTGQVAATKQ 280
P+D G + T + A D D G N + +S ++G+ +++ N G+V +
Sbjct: 1429 PEDCPVGQRVAT----VKAWDPDAGSNGQVVFSLASGNIAGAFEIVTTNDSIGEVFVARP 1484
Query: 281 LIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEG 340
L E + + A+ P R L + Y+ +V+E
Sbjct: 1485 LDREELDHYILQVVASDRGTPPRKKDHILQVTILDINDNPPVIE----SPFGYNVSVNEN 1540
Query: 341 ASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAINN-AGEVILRRS-LDYETTSN 398
G+ ++ + ++ S L +Y+++ + F ++ +GE+ R + D E S
Sbjct: 1541 VGGGTAVVQVRATDRDIGI-NSVLSYYITEGNKDMTFRMDRISGEIATRPAPPDRERQSF 1599
Query: 399 YFYQVMVTDS---ISNDTASINISVEDVNEWEPRFRHPQYE 436
Y V D + T + +++ D N+ P F+ P YE
Sbjct: 1600 YHLVATVEDEGTPTLSATTHVYVTIVDENDNAPMFQQPHYE 1640
Score = 56.0 bits (129), Expect = 6e-07
Identities = 74/355 (20%), Positives = 144/355 (40%), Gaps = 30/355 (8%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
V + + + NDN P + Y + + E +D D G + Y P
Sbjct: 446 VKITLINENDNRPIFSQPLYNISLYENVTVGTSVLTVLATDNDA-GTFGEVSYFFSDDP- 503
Query: 154 SEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNP 213
+ + + I+++ + LD+E + FT+ + +D G + +++ VLD +D P
Sbjct: 504 -DRFSLDKDTGLIMLIAR-LDYELIQRFTLTIIARDGGGEE--TTGRVRINVLDVNDNVP 559
Query: 214 KFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQY-----SSTGDHKQLIVV 268
F + Y L ++ T L + A D+D N + Y S+ G + I +
Sbjct: 560 TFQKDAYVGALRENEPSVTQLVR----LRATDEDSPPNNQITYSIVSASAFGSYFD-ISL 614
Query: 269 NKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQF 328
+ G ++ ++ L E + I L +D + +T+ F
Sbjct: 615 YEGYGVISVSRPLDYEQISNGLIYLTVMAMDAGNPPLNSTVPVTIEVFDENDNPPT---F 671
Query: 329 TQKQYSTTVSEGASPGSVLLTL--TTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEV 385
++ Y +V E G+ +L L T + ++ E+ + + + + + +F IN +GE+
Sbjct: 672 SKPAYFVSVVENIMAGATVLFLNATDLDRSREYGQESIIYSLEGST---QFRINARSGEI 728
Query: 386 ILRRSLDYETTSNYFYQVMVTD-----SISNDTASINISVEDVNEWEPRFRHPQY 435
LD ET S Y V D + A++NI++ D+N+ P ++ Y
Sbjct: 729 TTTSLLDRETKSEYILIVRAVDGGVGHNQKTGIATVNITLLDINDNHPTWKDAPY 783
Score = 54.0 bits (124), Expect = 2e-06
Identities = 66/247 (26%), Positives = 110/247 (44%), Gaps = 29/247 (11%)
Query: 50 IVPGSKNLTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQW- 108
I P S + + LDRE + S + V D + + P+ V + D++DN P +
Sbjct: 2666 IDPISGLIQTAQRLDRESQAVYSLILV--ASDLGQPVPYETMQPLQVALEDIDDNEPLFV 2723
Query: 109 ---EGAPY--AVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENEL 163
+G+P + V E + GP++ ++Y + G +E F +
Sbjct: 2724 RPPKGSPQYQLLTVPEHSPRGTLVGNVTGAVDADEGPNAIVYYFIAAG--NEEKNFHLQP 2781
Query: 164 EPIIVVKKPLDFE--TVNNFTIKLRVQDQGSPP--------LYSDTTLQ---VTVLDADD 210
+ ++V + LD E + +F +K +PP L +D TLQ V + D +D
Sbjct: 2782 DGCLLVLRDLDREREAIFSFIVKASSNRSWTPPRGPSPTLDLVADLTLQEVRVVLEDIND 2841
Query: 211 QNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDH--KQLIVV 268
Q P+FT YTA + DA+ G+ L + A D D+G N+ + YS H + L
Sbjct: 2842 QPPRFTKAEYTAGVATDAKVGSELI----QVLALDADIGNNSLVFYSILAIHYFRALAND 2897
Query: 269 NKDTGQV 275
++D GQV
Sbjct: 2898 SEDVGQV 2904
Score = 50.0 bits (114), Expect = 4e-05
Identities = 55/227 (24%), Positives = 92/227 (40%), Gaps = 12/227 (5%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRA---LDREE 67
+ ED P G I L + G + R+ N L+R LDRE
Sbjct: 1111 VPEDIPEGHSILQLKATDADEGEFGRVWYRILHGNHGNNFRIHVSNGLLMRGPRPLDRER 1170
Query: 68 KIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYA-VRVSETXXXXXX 126
S+V + V + V V V D+ND AP + Y+ + + ET
Sbjct: 1171 N--SSHVLI-VEAYNHDLGPMRSSVRVIVYVEDINDEAPVFTQQQYSRLGLRETAGIGTS 1227
Query: 127 XXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFE-NELEPIIVVKKPLDFETVNNFTIKL 185
+DRD G ++Y +L G + FE +E +I+ LD+ET ++ + +
Sbjct: 1228 VIVVQATDRDS-GDGGLVNYRILSGAEGK---FEIDESTGLIITVNYLDYETKTSYMMNV 1283
Query: 186 RVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGT 232
DQ P ++ +T+L+ D+ +F+ Y A + ++ GT
Sbjct: 1284 SATDQAPPFNQGFCSVYITLLNELDEAVQFSNASYEAAILENLALGT 1330
Score = 44.8 bits (101), Expect = 0.001
Identities = 36/111 (32%), Positives = 50/111 (45%), Gaps = 7/111 (6%)
Query: 328 FTQKQYST--TVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGE 384
FT + T +SE GS + L + + PL F VS FA+ + G
Sbjct: 31 FTNHFFDTYLLISEDTPVGSSVTQLLAQDMDND----PLVFGVSGEEASRFFAVEPDTGV 86
Query: 385 VILRRSLDYETTSNYFYQVMVTDSISNDTASINISVEDVNEWEPRFRHPQY 435
V LR+ LD ET S + + V+D T +NI V DVN+ P F + Y
Sbjct: 87 VWLRQPLDRETKSEFTVEFSVSDHQGVITRKVNIQVGDVNDNAPTFHNQPY 137
>AF152514-1|AAD43774.1| 817|Homo sapiens protocadherin gamma A7
short form protein protein.
Length = 817
Score = 99.1 bits (236), Expect = 6e-20
Identities = 103/441 (23%), Positives = 181/441 (41%), Gaps = 30/441 (6%)
Query: 9 FFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRA--LDR 65
+ +SE+T GS +G ++ + G +L + +R+ +G ++ +L+ A +DR
Sbjct: 33 YSVSEETDKGSFVGDIAKDLGLEPRELAERGVRIISRGRTQLFALNQRSGSLVTAGRIDR 92
Query: 66 EEKIGPS-NVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXX 124
EE S VN D + P+ V + D+NDN P++ V++ E
Sbjct: 93 EEICAQSARCLVNFNI---LMEDKMNLYPIDVEIIDINDNVPRFLTEEINVKIMENTAPG 149
Query: 125 XXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYL---GFENELEPIIVVKKPLDFETVNNF 181
D D G +S Y + P H G + P +V+++ LD E
Sbjct: 150 VRFPLSEAGDPDV-GTNSLQSYQLSPNRHFSLAVQSGDDETKYPELVLERVLDREEERVH 208
Query: 182 TIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPI 241
+ L D G PP S +QVTV+D +D P F+ Y +P++ GT L T +
Sbjct: 209 HLVLTASDGGDPPRSSTAHIQVTVVDVNDHTPVFSLPQYQVTVPENVPVGTRLLT----V 264
Query: 242 SAADQDLGINAPLQYS---STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQV 298
A D D G+N + YS T ++ +N TG+++ + L + + + ++
Sbjct: 265 HAIDLDEGVNGEVTYSFRKITPKLPKMFHLNSLTGEISTLEGL--DYEETAFYEMEVQAQ 322
Query: 299 DNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTE 358
D P +L + T S+++ E G+V+ +++
Sbjct: 323 DGP-----GSLTKAKVLITVLDVNDNAPEVTMTSLSSSIPEDTPLGTVIALFYLQDRDSG 377
Query: 359 FRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDS----ISNDTA 414
+ F + +I+N ++ ++LD ET S Y + TD +S +T
Sbjct: 378 KNGEVTCTIPENLPFKLEKSIDNYYRLVTTKNLDRETLSLYNITLKATDGGTPPLSRET- 436
Query: 415 SINISVEDVNEWEPRFRHPQY 435
I + V D N+ P F H Y
Sbjct: 437 HIFMQVADTNDNPPTFPHSSY 457
Score = 76.2 bits (179), Expect = 5e-13
Identities = 75/313 (23%), Positives = 122/313 (38%), Gaps = 22/313 (7%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEK--GAAVGIVPGSKNLTLLRALDREEK 68
I EDTP+G++I + S G++T + E + L + LDRE
Sbjct: 356 IPEDTPLGTVIALFYLQDRDSGKNGEVTCTIPENLPFKLEKSIDNYYRLVTTKNLDRETL 415
Query: 69 IGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXX 128
S + ++ T S + ++V D NDN P + + Y+V ++E
Sbjct: 416 ---SLYNITLKATDGGTPPLSRETHIFMQVADTNDNPPTFPHSSYSVYIAENNPRGASIF 472
Query: 129 XXXXSDRDQPG----PHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIK 184
D D +S + P S Y+ ++ ++ + D+E + ++
Sbjct: 473 LVTAQDHDSEDNAQITYSLAEDTIQGAPVSSYVSINSDTG-VLYALQSFDYEQLRELQLR 531
Query: 185 LRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFL---TTSPG-- 239
+ D G PPL S+ +L + VLD +D P+ Y LP D G L + PG
Sbjct: 532 VTAHDSGDPPLSSNMSLSLFVLDQNDNPPEILY----PALPTDGSTGMELAPRSAEPGYL 587
Query: 240 --PISAADQDLGINAPLQY-SSTGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKAT 296
+ A D+D G NA L Y L V TG+V + L+ ++V+
Sbjct: 588 VTKVVAVDKDSGQNAWLSYLLLKASEPGLFAVGLYTGEVRTARALLDRDALKQSLVVAVQ 647
Query: 297 QVDNPDRYALATL 309
P A TL
Sbjct: 648 DHGQPPLSATVTL 660
Score = 63.7 bits (148), Expect = 3e-09
Identities = 55/217 (25%), Positives = 93/217 (42%), Gaps = 18/217 (8%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
V + V DVNDNAP+ + + E DRD G + + + P
Sbjct: 333 VLITVLDVNDNAPEVTMTSLSSSIPEDTPLGTVIALFYLQDRDS-GKNGEVTCTI---PE 388
Query: 154 SEYLGFENELEPI--IVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQ 211
+ E ++ +V K LD ET++ + I L+ D G+PPL +T + + V D +D
Sbjct: 389 NLPFKLEKSIDNYYRLVTTKNLDRETLSLYNITLKATDGGTPPLSRETHIFMQVADTNDN 448
Query: 212 NPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQ------L 265
P F + Y+ + ++ G + ++A D D NA + YS D Q
Sbjct: 449 PPTFPHSSYSVYIAENNPRGASIFL----VTAQDHDSEDNAQITYSLAEDTIQGAPVSSY 504
Query: 266 IVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPD 302
+ +N DTG + A + + + + L+ T D+ D
Sbjct: 505 VSINSDTGVLYALQSF--DYEQLRELQLRVTAHDSGD 539
Score = 37.9 bits (84), Expect = 0.16
Identities = 50/212 (23%), Positives = 83/212 (39%), Gaps = 13/212 (6%)
Query: 8 SFFISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQE---KGAAVG-IVPGSKNLTLLRAL 63
S +I+E+ P G+ I ++ SED IT L E +GA V V + + +L AL
Sbjct: 458 SVYIAENNPRGASIFLVTAQDHDSEDNAQITYSLAEDTIQGAPVSSYVSINSDTGVLYAL 517
Query: 64 DREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQ-------WEGAPYAVR 116
+ + + V S + +S+ V D NDN P+ +G+
Sbjct: 518 QSFDYEQLRELQLRVTAHDSGDPPLSSNMSLSLFVLDQNDNPPEILYPALPTDGSTGMEL 577
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFE 176
+ D+D G ++ L Y +L + + LD +
Sbjct: 578 APRSAEPGYLVTKVVAVDKDS-GQNAWLSYLLLKASEPGLFAVGLYTGEVRTARALLDRD 636
Query: 177 TVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDA 208
+ ++ + VQD G PPL + TL V V D+
Sbjct: 637 ALKQ-SLVVAVQDHGQPPLSATVTLTVAVADS 667
Score = 32.3 bits (70), Expect = 7.9
Identities = 19/56 (33%), Positives = 29/56 (51%), Gaps = 3/56 (5%)
Query: 384 EVILRRSLDYETTSNYFYQVMVTDSIS---NDTASINISVEDVNEWEPRFRHPQYE 436
E++L R LD E + + +D + TA I ++V DVN+ P F PQY+
Sbjct: 193 ELVLERVLDREEERVHHLVLTASDGGDPPRSSTAHIQVTVVDVNDHTPVFSLPQYQ 248
>AF152327-1|AAD43721.1| 932|Homo sapiens protocadherin gamma A7
protein.
Length = 932
Score = 99.1 bits (236), Expect = 6e-20
Identities = 103/441 (23%), Positives = 181/441 (41%), Gaps = 30/441 (6%)
Query: 9 FFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRA--LDR 65
+ +SE+T GS +G ++ + G +L + +R+ +G ++ +L+ A +DR
Sbjct: 33 YSVSEETDKGSFVGDIAKDLGLEPRELAERGVRIISRGRTQLFALNQRSGSLVTAGRIDR 92
Query: 66 EEKIGPS-NVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXX 124
EE S VN D + P+ V + D+NDN P++ V++ E
Sbjct: 93 EEICAQSARCLVNFNI---LMEDKMNLYPIDVEIIDINDNVPRFLTEEINVKIMENTAPG 149
Query: 125 XXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYL---GFENELEPIIVVKKPLDFETVNNF 181
D D G +S Y + P H G + P +V+++ LD E
Sbjct: 150 VRFPLSEAGDPDV-GTNSLQSYQLSPNRHFSLAVQSGDDETKYPELVLERVLDREEERVH 208
Query: 182 TIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPI 241
+ L D G PP S +QVTV+D +D P F+ Y +P++ GT L T +
Sbjct: 209 HLVLTASDGGDPPRSSTAHIQVTVVDVNDHTPVFSLPQYQVTVPENVPVGTRLLT----V 264
Query: 242 SAADQDLGINAPLQYS---STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQV 298
A D D G+N + YS T ++ +N TG+++ + L + + + ++
Sbjct: 265 HAIDLDEGVNGEVTYSFRKITPKLPKMFHLNSLTGEISTLEGL--DYEETAFYEMEVQAQ 322
Query: 299 DNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTE 358
D P +L + T S+++ E G+V+ +++
Sbjct: 323 DGP-----GSLTKAKVLITVLDVNDNAPEVTMTSLSSSIPEDTPLGTVIALFYLQDRDSG 377
Query: 359 FRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDS----ISNDTA 414
+ F + +I+N ++ ++LD ET S Y + TD +S +T
Sbjct: 378 KNGEVTCTIPENLPFKLEKSIDNYYRLVTTKNLDRETLSLYNITLKATDGGTPPLSRET- 436
Query: 415 SINISVEDVNEWEPRFRHPQY 435
I + V D N+ P F H Y
Sbjct: 437 HIFMQVADTNDNPPTFPHSSY 457
Score = 76.2 bits (179), Expect = 5e-13
Identities = 75/313 (23%), Positives = 122/313 (38%), Gaps = 22/313 (7%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEK--GAAVGIVPGSKNLTLLRALDREEK 68
I EDTP+G++I + S G++T + E + L + LDRE
Sbjct: 356 IPEDTPLGTVIALFYLQDRDSGKNGEVTCTIPENLPFKLEKSIDNYYRLVTTKNLDRETL 415
Query: 69 IGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXX 128
S + ++ T S + ++V D NDN P + + Y+V ++E
Sbjct: 416 ---SLYNITLKATDGGTPPLSRETHIFMQVADTNDNPPTFPHSSYSVYIAENNPRGASIF 472
Query: 129 XXXXSDRDQPG----PHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIK 184
D D +S + P S Y+ ++ ++ + D+E + ++
Sbjct: 473 LVTAQDHDSEDNAQITYSLAEDTIQGAPVSSYVSINSDTG-VLYALQSFDYEQLRELQLR 531
Query: 185 LRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFL---TTSPG-- 239
+ D G PPL S+ +L + VLD +D P+ Y LP D G L + PG
Sbjct: 532 VTAHDSGDPPLSSNMSLSLFVLDQNDNPPEILY----PALPTDGSTGMELAPRSAEPGYL 587
Query: 240 --PISAADQDLGINAPLQY-SSTGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKAT 296
+ A D+D G NA L Y L V TG+V + L+ ++V+
Sbjct: 588 VTKVVAVDKDSGQNAWLSYLLLKASEPGLFAVGLYTGEVRTARALLDRDALKQSLVVAVQ 647
Query: 297 QVDNPDRYALATL 309
P A TL
Sbjct: 648 DHGQPPLSATVTL 660
Score = 63.7 bits (148), Expect = 3e-09
Identities = 55/217 (25%), Positives = 93/217 (42%), Gaps = 18/217 (8%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
V + V DVNDNAP+ + + E DRD G + + + P
Sbjct: 333 VLITVLDVNDNAPEVTMTSLSSSIPEDTPLGTVIALFYLQDRDS-GKNGEVTCTI---PE 388
Query: 154 SEYLGFENELEPI--IVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQ 211
+ E ++ +V K LD ET++ + I L+ D G+PPL +T + + V D +D
Sbjct: 389 NLPFKLEKSIDNYYRLVTTKNLDRETLSLYNITLKATDGGTPPLSRETHIFMQVADTNDN 448
Query: 212 NPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQ------L 265
P F + Y+ + ++ G + ++A D D NA + YS D Q
Sbjct: 449 PPTFPHSSYSVYIAENNPRGASIFL----VTAQDHDSEDNAQITYSLAEDTIQGAPVSSY 504
Query: 266 IVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPD 302
+ +N DTG + A + + + + L+ T D+ D
Sbjct: 505 VSINSDTGVLYALQSF--DYEQLRELQLRVTAHDSGD 539
Score = 37.9 bits (84), Expect = 0.16
Identities = 50/212 (23%), Positives = 83/212 (39%), Gaps = 13/212 (6%)
Query: 8 SFFISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQE---KGAAVG-IVPGSKNLTLLRAL 63
S +I+E+ P G+ I ++ SED IT L E +GA V V + + +L AL
Sbjct: 458 SVYIAENNPRGASIFLVTAQDHDSEDNAQITYSLAEDTIQGAPVSSYVSINSDTGVLYAL 517
Query: 64 DREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQ-------WEGAPYAVR 116
+ + + V S + +S+ V D NDN P+ +G+
Sbjct: 518 QSFDYEQLRELQLRVTAHDSGDPPLSSNMSLSLFVLDQNDNPPEILYPALPTDGSTGMEL 577
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFE 176
+ D+D G ++ L Y +L + + LD +
Sbjct: 578 APRSAEPGYLVTKVVAVDKDS-GQNAWLSYLLLKASEPGLFAVGLYTGEVRTARALLDRD 636
Query: 177 TVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDA 208
+ ++ + VQD G PPL + TL V V D+
Sbjct: 637 ALKQ-SLVVAVQDHGQPPLSATVTLTVAVADS 667
Score = 32.3 bits (70), Expect = 7.9
Identities = 19/56 (33%), Positives = 29/56 (51%), Gaps = 3/56 (5%)
Query: 384 EVILRRSLDYETTSNYFYQVMVTDSIS---NDTASINISVEDVNEWEPRFRHPQYE 436
E++L R LD E + + +D + TA I ++V DVN+ P F PQY+
Sbjct: 193 ELVLERVLDREEERVHHLVLTASDGGDPPRSSTAHIQVTVVDVNDHTPVFSLPQYQ 248
>AF282973-3|AAG10032.1| 536|Homo sapiens protocadherin-beta9
protein.
Length = 536
Score = 98.7 bits (235), Expect = 8e-20
Identities = 97/392 (24%), Positives = 165/392 (42%), Gaps = 30/392 (7%)
Query: 56 NLTLLRALDREEKIGPSN---VYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAP 112
NL LDRE+ GP +Y + D DP + +RV D+ND++P +
Sbjct: 83 NLLTNEKLDREKLCGPKEPCMLYFQILMD-----DPFQIYRAELRVSDINDHSPVFRHKE 137
Query: 113 YAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGP--HSEYLGF-ENELEPIIVV 169
+++SE D D+ G +S +Y + H + G E + P +V+
Sbjct: 138 MVLKISENTAEGTAFRLERAQDPDE-GHNSIQNYTISSNSFFHIKISGSDEGMIYPELVL 196
Query: 170 KKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAE 229
K LD E ++ L D GSP +T+++ VLD +D P+F Y P+++
Sbjct: 197 DKALDREEQEELSLTLTALDGGSPSRSGTSTIRIVVLDVNDNAPQFAQALYETQAPENSP 256
Query: 230 EGTFLTTSPGPISAADQDLGINAPLQYS---STGDHKQLIVVNKDTGQVAATKQLIAELD 286
G+ + +SA D D G+NA + YS ++ D +N +G++ + L EL
Sbjct: 257 VGSLIV----KVSAGDADSGVNAEVSYSFFDASEDILTTFQINPFSGEIFLRELLDYELV 312
Query: 287 PSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSV 346
S I ++A +D A T+ + S +V+E SPG V
Sbjct: 313 NSYKINIQA--MDGGGLSARCTVLIKVLDSNDNPP-----ELIISSLSNSVAEN-SPGIV 364
Query: 347 LLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVT 406
L +++ + + + F K +++N ++ +LD E+ + Y + VT
Sbjct: 365 LAVFKIKDRDSGENGKTICYVQDNLPFFLKPSVDNFYILMTEGALDRESKAEYNITITVT 424
Query: 407 DSIS---NDTASINISVEDVNEWEPRFRHPQY 435
D + SI + V DVN+ P F Y
Sbjct: 425 DMGTPRLKTEHSITLQVSDVNDNAPAFTQTSY 456
Score = 56.0 bits (129), Expect = 6e-07
Identities = 50/194 (25%), Positives = 82/194 (42%), Gaps = 13/194 (6%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
V ++V D NDN P+ + + V+E DRD + Y P
Sbjct: 333 VLIKVLDSNDNPPELIISSLSNSVAENSPGIVLAVFKI-KDRDSGENGKTICYVQDNLPF 391
Query: 154 SEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNP 213
+N I++ + LD E+ + I + V D G+P L ++ ++ + V D +D P
Sbjct: 392 FLKPSVDNFY--ILMTEGALDRESKAEYNITITVTDMGTPRLKTEHSITLQVSDVNDNAP 449
Query: 214 KFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYS---STGDH---KQLIV 267
FT YT + ++ + G +SA D+D G NA + YS H L+
Sbjct: 450 AFTQTSYTLFVRENNSPALHI----GSVSATDRDSGTNAQVTYSLLPPQDPHLPLASLVS 505
Query: 268 VNKDTGQVAATKQL 281
+N D G + A + L
Sbjct: 506 INADNGHLFALRSL 519
Score = 37.9 bits (84), Expect = 0.16
Identities = 59/279 (21%), Positives = 104/279 (37%), Gaps = 22/279 (7%)
Query: 226 DDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLIAE- 284
++ E+G+F+ + A+ +L S D+KQ ++++ TG + ++L E
Sbjct: 37 EETEKGSFVVNLAKDLGLAEGELAARGTRVVSD--DNKQYLLLDSHTGNLLTNEKLDREK 94
Query: 285 -LDPSVTIVLK-ATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGAS 342
P +L +D+P + A L F K+ +SE +
Sbjct: 95 LCGPKEPCMLYFQILMDDPFQIYRAELRVSDINDHSPV-------FRHKEMVLKISENTA 147
Query: 343 PGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLD-KFAINNAG----EVILRRSLDYETTS 397
G+ L E S + +S SF K + ++ G E++L ++LD E
Sbjct: 148 EGTAF-RLERAQDPDEGHNSIQNYTISSNSFFHIKISGSDEGMIYPELVLDKALDREEQE 206
Query: 398 NYFYQVMVTDSIS---NDTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXX 454
+ D S + T++I I V DVN+ P+F YE +
Sbjct: 207 ELSLTLTALDGGSPSRSGTSTIRIVVLDVNDNAPQFAQALYETQAPENSPVGSLIVKVSA 266
Query: 455 XXXXVAHDGDAGTLALSLAGQHARMFYINA-SGDLFLRE 492
+ + + F IN SG++FLRE
Sbjct: 267 GDADSGVNAEVSYSFFDASEDILTTFQINPFSGEIFLRE 305
>AF217749-1|AAF81913.1| 797|Homo sapiens protocadherin beta 9
protein.
Length = 797
Score = 98.7 bits (235), Expect = 8e-20
Identities = 97/392 (24%), Positives = 165/392 (42%), Gaps = 30/392 (7%)
Query: 56 NLTLLRALDREEKIGPSN---VYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAP 112
NL LDRE+ GP +Y + D DP + +RV D+ND++P +
Sbjct: 83 NLLTNEKLDREKLCGPKEPCMLYFQILMD-----DPFQIYRAELRVSDINDHSPVFRHKE 137
Query: 113 YAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGP--HSEYLGF-ENELEPIIVV 169
+++SE D D+ G +S +Y + H + G E + P +V+
Sbjct: 138 MVLKISENTAEGTAFRLERAQDPDE-GHNSIQNYTISSNSFFHIKISGSDEGMIYPELVL 196
Query: 170 KKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAE 229
K LD E ++ L D GSP +T+++ VLD +D P+F Y P+++
Sbjct: 197 DKALDREEQEELSLTLTALDGGSPSRSGTSTIRIVVLDVNDNAPQFAQALYETQAPENSP 256
Query: 230 EGTFLTTSPGPISAADQDLGINAPLQYS---STGDHKQLIVVNKDTGQVAATKQLIAELD 286
G+ + +SA D D G+NA + YS ++ D +N +G++ + L EL
Sbjct: 257 VGSLIV----KVSAGDADSGVNAEVSYSFFDASEDILTTFQINPFSGEIFLRELLDYELV 312
Query: 287 PSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSV 346
S I ++A +D A T+ + S +V+E SPG V
Sbjct: 313 NSYKINIQA--MDGGGLSARCTVLIKVLDSNDNPP-----ELIISSLSNSVAEN-SPGIV 364
Query: 347 LLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVT 406
L +++ + + + F K +++N ++ +LD E+ + Y + VT
Sbjct: 365 LAVFKIKDRDSGENGKTICYVQDNLPFFLKPSVDNFYILMTEGALDRESKAEYNITITVT 424
Query: 407 DSIS---NDTASINISVEDVNEWEPRFRHPQY 435
D + SI + V DVN+ P F Y
Sbjct: 425 DMGTPRLKTEHSITLQVSDVNDNAPAFTQTSY 456
Score = 81.0 bits (191), Expect = 2e-14
Identities = 90/316 (28%), Positives = 136/316 (43%), Gaps = 30/316 (9%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLR---ALDREE 67
++E++P G ++ + S + G +Q+ + P N +L ALDRE
Sbjct: 356 VAENSP-GIVLAVFKIKDRDSGENGKTICYVQDN-LPFFLKPSVDNFYILMTEGALDRES 413
Query: 68 KIGPSNVYVNVRC--DRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXX 125
K N+ + V R T+ S + VS DVNDNAP + Y + V E
Sbjct: 414 K-AEYNITITVTDMGTPRLKTEHSITLQVS----DVNDNAPAFTQTSYTLFVRENNSPAL 468
Query: 126 XXXXXXXSDRDQPGPHSALHYAVLP--GPHSEYLGFE--NELEPIIVVKKPLDFETVNNF 181
+DRD G ++ + Y++LP PH N + + LD+E + F
Sbjct: 469 HIGSVSATDRDS-GTNAQVTYSLLPPQDPHLPLASLVSINADNGHLFALRSLDYEALQAF 527
Query: 182 TIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTY------EHYTALLPDDAEEGTFLT 235
++ D+GSP L S+ ++V VLDA+D +P Y T L+P AE G +T
Sbjct: 528 DFRVGASDRGSPALSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVT 587
Query: 236 TSPGPISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPSV-TIVL 293
+ A D D G NA L Y L V G+V T +L++E D + +V+
Sbjct: 588 ----KVVAVDGDSGQNAWLSYQLLKATEPGLFGVWAHNGEV-RTARLLSERDAAKHRLVV 642
Query: 294 KATQVDNPDRYALATL 309
P R A ATL
Sbjct: 643 LVKDNGEPPRSATATL 658
Score = 70.5 bits (165), Expect = 2e-11
Identities = 110/478 (23%), Positives = 175/478 (36%), Gaps = 30/478 (6%)
Query: 57 LTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVR 116
L L +ALDREE+ + + + + S + + V DVNDNAPQ+ A Y +
Sbjct: 194 LVLDKALDREEQ---EELSLTLTALDGGSPSRSGTSTIRIVVLDVNDNAPQFAQALYETQ 250
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFE-NELEPIIVVKKPLDF 175
E D D G ++ + Y+ F+ N I +++ LD+
Sbjct: 251 APENSPVGSLIVKVSAGDADS-GVNAEVSYSFFDASEDILTTFQINPFSGEIFLRELLDY 309
Query: 176 ETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLT 235
E VN++ I ++ D G L + T+ + VLD++D P+ + + +++ G L
Sbjct: 310 ELVNSYKINIQAMDGGG--LSARCTVLIKVLDSNDNPPELIISSLSNSVAENSP-GIVLA 366
Query: 236 TSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATK-QLIAELDPSVTIVLK 294
D+D G N + + + D + T+ L E I +
Sbjct: 367 V----FKIKDRDSGENGKTICYVQDNLPFFLKPSVDNFYILMTEGALDRESKAEYNITIT 422
Query: 295 ATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASP----GSVLLTL 350
T + P L T FTQ Y+ V E SP GSV T
Sbjct: 423 VTDMGTP---RLKTEHSITLQVSDVNDNAPA--FTQTSYTLFVRENNSPALHIGSVSATD 477
Query: 351 TTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTDSI 409
N + S L +IN + G + RSLDYE + ++V +D
Sbjct: 478 RDSGTNAQVTYSLLPPQDPHLPLASLVSINADNGHLFALRSLDYEALQAFDFRVGASDRG 537
Query: 410 S---NDTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGDAG 466
S + A + + V D N+ P +P VA DGD+G
Sbjct: 538 SPALSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVTKVVAVDGDSG 597
Query: 467 TLA-LS---LAGQHARMFYINASGDLFLREEAIGNLNSSSLHLVATAIDSGIPPRQTS 520
A LS L +F + A + +++ LV D+G PPR +
Sbjct: 598 QNAWLSYQLLKATEPGLFGVWAHNGEVRTARLLSERDAAKHRLVVLVKDNGEPPRSAT 655
Score = 37.9 bits (84), Expect = 0.16
Identities = 59/279 (21%), Positives = 104/279 (37%), Gaps = 22/279 (7%)
Query: 226 DDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLIAE- 284
++ E+G+F+ + A+ +L S D+KQ ++++ TG + ++L E
Sbjct: 37 EETEKGSFVVNLAKDLGLAEGELAARGTRVVSD--DNKQYLLLDSHTGNLLTNEKLDREK 94
Query: 285 -LDPSVTIVLK-ATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGAS 342
P +L +D+P + A L F K+ +SE +
Sbjct: 95 LCGPKEPCMLYFQILMDDPFQIYRAELRVSDINDHSPV-------FRHKEMVLKISENTA 147
Query: 343 PGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLD-KFAINNAG----EVILRRSLDYETTS 397
G+ L E S + +S SF K + ++ G E++L ++LD E
Sbjct: 148 EGTAF-RLERAQDPDEGHNSIQNYTISSNSFFHIKISGSDEGMIYPELVLDKALDREEQE 206
Query: 398 NYFYQVMVTDSIS---NDTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXX 454
+ D S + T++I I V DVN+ P+F YE +
Sbjct: 207 ELSLTLTALDGGSPSRSGTSTIRIVVLDVNDNAPQFAQALYETQAPENSPVGSLIVKVSA 266
Query: 455 XXXXVAHDGDAGTLALSLAGQHARMFYINA-SGDLFLRE 492
+ + + F IN SG++FLRE
Sbjct: 267 GDADSGVNAEVSYSFFDASEDILTTFQINPFSGEIFLRE 305
>BC105640-1|AAI05641.1| 797|Homo sapiens protocadherin beta 9
protein.
Length = 797
Score = 98.3 bits (234), Expect = 1e-19
Identities = 97/392 (24%), Positives = 165/392 (42%), Gaps = 30/392 (7%)
Query: 56 NLTLLRALDREEKIGPSN---VYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAP 112
NL LDRE+ GP +Y + D DP + +RV D+ND++P +
Sbjct: 83 NLLTNEKLDREKLCGPKEPCMLYFQILMD-----DPFQIYRAELRVRDINDHSPVFRHKE 137
Query: 113 YAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGP--HSEYLGF-ENELEPIIVV 169
+++SE D D+ G +S +Y + H + G E + P +V+
Sbjct: 138 MVLKISENTAEGTAFRLERAQDPDE-GHNSIQNYTISSNSFFHIKISGSDEGMIYPELVL 196
Query: 170 KKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAE 229
K LD E ++ L D GSP +T+++ VLD +D P+F Y P+++
Sbjct: 197 DKALDREEQEELSLTLTALDGGSPSRSGTSTIRIVVLDVNDNAPQFAQALYETQAPENSP 256
Query: 230 EGTFLTTSPGPISAADQDLGINAPLQYS---STGDHKQLIVVNKDTGQVAATKQLIAELD 286
G+ + +SA D D G+NA + YS ++ D +N +G++ + L EL
Sbjct: 257 VGSLIV----KVSAGDADSGVNAEVSYSFFDASEDILTTFQINPFSGEIFLRELLDYELV 312
Query: 287 PSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSV 346
S I ++A +D A T+ + S +V+E SPG V
Sbjct: 313 NSYKINIQA--MDGGGLSARCTVLIKVLDSNDNPP-----ELIISSLSNSVAEN-SPGIV 364
Query: 347 LLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVT 406
L +++ + + + F K +++N ++ +LD E+ + Y + VT
Sbjct: 365 LAVFKIKDRDSGENGKTICYVQDNLPFFLKPSVDNFYILMTEGALDRESKAEYNITITVT 424
Query: 407 DSIS---NDTASINISVEDVNEWEPRFRHPQY 435
D + SI + V DVN+ P F Y
Sbjct: 425 DLGTPRLKTEHSITLQVSDVNDNAPAFTQTSY 456
Score = 81.0 bits (191), Expect = 2e-14
Identities = 90/316 (28%), Positives = 136/316 (43%), Gaps = 30/316 (9%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLR---ALDREE 67
++E++P G ++ + S + G +Q+ + P N +L ALDRE
Sbjct: 356 VAENSP-GIVLAVFKIKDRDSGENGKTICYVQDN-LPFFLKPSVDNFYILMTEGALDRES 413
Query: 68 KIGPSNVYVNVRC--DRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXX 125
K N+ + V R T+ S + VS DVNDNAP + Y + V E
Sbjct: 414 K-AEYNITITVTDLGTPRLKTEHSITLQVS----DVNDNAPAFTQTSYTLFVRENNSPAL 468
Query: 126 XXXXXXXSDRDQPGPHSALHYAVLP--GPHSEYLGFE--NELEPIIVVKKPLDFETVNNF 181
+DRD G ++ + Y++LP PH N + + LD+E + F
Sbjct: 469 HIGSVSATDRDS-GTNAQVTYSLLPPQDPHLPLASLVSINADNGHLFALRSLDYEALQAF 527
Query: 182 TIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTY------EHYTALLPDDAEEGTFLT 235
++ D+GSP L S+ ++V VLDA+D +P Y T L+P AE G +T
Sbjct: 528 DFRVGASDRGSPALSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVT 587
Query: 236 TSPGPISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPSV-TIVL 293
+ A D D G NA L Y L V G+V T +L++E D + +V+
Sbjct: 588 ----KVVAVDGDSGQNAWLSYQLLKATEPGLFGVWAHNGEV-RTARLLSERDAAKHRLVV 642
Query: 294 KATQVDNPDRYALATL 309
P R A ATL
Sbjct: 643 LVKDNGEPPRSATATL 658
Score = 70.5 bits (165), Expect = 2e-11
Identities = 110/478 (23%), Positives = 175/478 (36%), Gaps = 30/478 (6%)
Query: 57 LTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVR 116
L L +ALDREE+ + + + + S + + V DVNDNAPQ+ A Y +
Sbjct: 194 LVLDKALDREEQ---EELSLTLTALDGGSPSRSGTSTIRIVVLDVNDNAPQFAQALYETQ 250
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFE-NELEPIIVVKKPLDF 175
E D D G ++ + Y+ F+ N I +++ LD+
Sbjct: 251 APENSPVGSLIVKVSAGDADS-GVNAEVSYSFFDASEDILTTFQINPFSGEIFLRELLDY 309
Query: 176 ETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLT 235
E VN++ I ++ D G L + T+ + VLD++D P+ + + +++ G L
Sbjct: 310 ELVNSYKINIQAMDGGG--LSARCTVLIKVLDSNDNPPELIISSLSNSVAENSP-GIVLA 366
Query: 236 TSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATK-QLIAELDPSVTIVLK 294
D+D G N + + + D + T+ L E I +
Sbjct: 367 V----FKIKDRDSGENGKTICYVQDNLPFFLKPSVDNFYILMTEGALDRESKAEYNITIT 422
Query: 295 ATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASP----GSVLLTL 350
T + P L T FTQ Y+ V E SP GSV T
Sbjct: 423 VTDLGTP---RLKTEHSITLQVSDVNDNAPA--FTQTSYTLFVRENNSPALHIGSVSATD 477
Query: 351 TTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTDSI 409
N + S L +IN + G + RSLDYE + ++V +D
Sbjct: 478 RDSGTNAQVTYSLLPPQDPHLPLASLVSINADNGHLFALRSLDYEALQAFDFRVGASDRG 537
Query: 410 S---NDTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGDAG 466
S + A + + V D N+ P +P VA DGD+G
Sbjct: 538 SPALSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVTKVVAVDGDSG 597
Query: 467 TLA-LS---LAGQHARMFYINASGDLFLREEAIGNLNSSSLHLVATAIDSGIPPRQTS 520
A LS L +F + A + +++ LV D+G PPR +
Sbjct: 598 QNAWLSYQLLKATEPGLFGVWAHNGEVRTARLLSERDAAKHRLVVLVKDNGEPPRSAT 655
Score = 37.5 bits (83), Expect = 0.21
Identities = 59/279 (21%), Positives = 104/279 (37%), Gaps = 22/279 (7%)
Query: 226 DDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLIAE- 284
++ E+G+F+ + A+ +L S D+KQ ++++ TG + ++L E
Sbjct: 37 EETEKGSFVVNLAKDLGLAEGELAARGTRVVSD--DNKQYLLLDSHTGNLLTNEKLDREK 94
Query: 285 -LDPSVTIVLK-ATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGAS 342
P +L +D+P + A L F K+ +SE +
Sbjct: 95 LCGPKEPCMLYFQILMDDPFQIYRAELRVRDINDHSPV-------FRHKEMVLKISENTA 147
Query: 343 PGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLD-KFAINNAG----EVILRRSLDYETTS 397
G+ L E S + +S SF K + ++ G E++L ++LD E
Sbjct: 148 EGTAF-RLERAQDPDEGHNSIQNYTISSNSFFHIKISGSDEGMIYPELVLDKALDREEQE 206
Query: 398 NYFYQVMVTDSIS---NDTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXX 454
+ D S + T++I I V DVN+ P+F YE +
Sbjct: 207 ELSLTLTALDGGSPSRSGTSTIRIVVLDVNDNAPQFAQALYETQAPENSPVGSLIVKVSA 266
Query: 455 XXXXVAHDGDAGTLALSLAGQHARMFYINA-SGDLFLRE 492
+ + + F IN SG++FLRE
Sbjct: 267 GDADSGVNAEVSYSFFDASEDILTTFQINPFSGEIFLRE 305
>BC103494-1|AAI03495.1| 796|Homo sapiens PCDHB9 protein protein.
Length = 796
Score = 98.3 bits (234), Expect = 1e-19
Identities = 97/392 (24%), Positives = 165/392 (42%), Gaps = 30/392 (7%)
Query: 56 NLTLLRALDREEKIGPSN---VYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAP 112
NL LDRE+ GP +Y + D DP + +RV D+ND++P +
Sbjct: 82 NLLTNEKLDREKLCGPKEPCMLYFQILMD-----DPFQIYRAELRVRDINDHSPVFRHKE 136
Query: 113 YAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGP--HSEYLGF-ENELEPIIVV 169
+++SE D D+ G +S +Y + H + G E + P +V+
Sbjct: 137 MVLKISENTAEGTAFRLERAQDPDE-GHNSIQNYTISSNSFFHIKISGSDEGMIYPELVL 195
Query: 170 KKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAE 229
K LD E ++ L D GSP +T+++ VLD +D P+F Y P+++
Sbjct: 196 DKALDREEQEELSLTLTALDGGSPSRSGTSTIRIVVLDVNDNAPQFAQALYETQAPENSP 255
Query: 230 EGTFLTTSPGPISAADQDLGINAPLQYS---STGDHKQLIVVNKDTGQVAATKQLIAELD 286
G+ + +SA D D G+NA + YS ++ D +N +G++ + L EL
Sbjct: 256 VGSLIV----KVSAGDADSGVNAEVSYSFFDASEDILTTFQINPFSGEIFLRELLDYELV 311
Query: 287 PSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSV 346
S I ++A +D A T+ + S +V+E SPG V
Sbjct: 312 NSYKINIQA--MDGGGLSARCTVLIKVLDSNDNPP-----ELIISSLSNSVAEN-SPGIV 363
Query: 347 LLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVT 406
L +++ + + + F K +++N ++ +LD E+ + Y + VT
Sbjct: 364 LAVFKIKDRDSGENGKTICYVQDNLPFFLKPSVDNFYILMTEGALDRESKAEYNITITVT 423
Query: 407 DSIS---NDTASINISVEDVNEWEPRFRHPQY 435
D + SI + V DVN+ P F Y
Sbjct: 424 DLGTPRLKTEHSITLQVSDVNDNAPAFTQTSY 455
Score = 81.0 bits (191), Expect = 2e-14
Identities = 90/316 (28%), Positives = 136/316 (43%), Gaps = 30/316 (9%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLR---ALDREE 67
++E++P G ++ + S + G +Q+ + P N +L ALDRE
Sbjct: 355 VAENSP-GIVLAVFKIKDRDSGENGKTICYVQDN-LPFFLKPSVDNFYILMTEGALDRES 412
Query: 68 KIGPSNVYVNVRC--DRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXX 125
K N+ + V R T+ S + VS DVNDNAP + Y + V E
Sbjct: 413 K-AEYNITITVTDLGTPRLKTEHSITLQVS----DVNDNAPAFTQTSYTLFVRENNSPAL 467
Query: 126 XXXXXXXSDRDQPGPHSALHYAVLP--GPHSEYLGFE--NELEPIIVVKKPLDFETVNNF 181
+DRD G ++ + Y++LP PH N + + LD+E + F
Sbjct: 468 HIGSVSATDRDS-GTNAQVTYSLLPPQDPHLPLASLVSINADNGHLFALRSLDYEALQAF 526
Query: 182 TIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTY------EHYTALLPDDAEEGTFLT 235
++ D+GSP L S+ ++V VLDA+D +P Y T L+P AE G +T
Sbjct: 527 DFRVGASDRGSPALSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVT 586
Query: 236 TSPGPISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPSV-TIVL 293
+ A D D G NA L Y L V G+V T +L++E D + +V+
Sbjct: 587 ----KVVAVDGDSGQNAWLSYQLLKATEPGLFGVWAHNGEV-RTARLLSERDAAKHRLVV 641
Query: 294 KATQVDNPDRYALATL 309
P R A ATL
Sbjct: 642 LVKDNGEPPRSATATL 657
Score = 70.5 bits (165), Expect = 2e-11
Identities = 110/478 (23%), Positives = 175/478 (36%), Gaps = 30/478 (6%)
Query: 57 LTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVR 116
L L +ALDREE+ + + + + S + + V DVNDNAPQ+ A Y +
Sbjct: 193 LVLDKALDREEQ---EELSLTLTALDGGSPSRSGTSTIRIVVLDVNDNAPQFAQALYETQ 249
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFE-NELEPIIVVKKPLDF 175
E D D G ++ + Y+ F+ N I +++ LD+
Sbjct: 250 APENSPVGSLIVKVSAGDADS-GVNAEVSYSFFDASEDILTTFQINPFSGEIFLRELLDY 308
Query: 176 ETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLT 235
E VN++ I ++ D G L + T+ + VLD++D P+ + + +++ G L
Sbjct: 309 ELVNSYKINIQAMDGGG--LSARCTVLIKVLDSNDNPPELIISSLSNSVAENSP-GIVLA 365
Query: 236 TSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATK-QLIAELDPSVTIVLK 294
D+D G N + + + D + T+ L E I +
Sbjct: 366 V----FKIKDRDSGENGKTICYVQDNLPFFLKPSVDNFYILMTEGALDRESKAEYNITIT 421
Query: 295 ATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASP----GSVLLTL 350
T + P L T FTQ Y+ V E SP GSV T
Sbjct: 422 VTDLGTP---RLKTEHSITLQVSDVNDNAPA--FTQTSYTLFVRENNSPALHIGSVSATD 476
Query: 351 TTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTDSI 409
N + S L +IN + G + RSLDYE + ++V +D
Sbjct: 477 RDSGTNAQVTYSLLPPQDPHLPLASLVSINADNGHLFALRSLDYEALQAFDFRVGASDRG 536
Query: 410 S---NDTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGDAG 466
S + A + + V D N+ P +P VA DGD+G
Sbjct: 537 SPALSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVTKVVAVDGDSG 596
Query: 467 TLA-LS---LAGQHARMFYINASGDLFLREEAIGNLNSSSLHLVATAIDSGIPPRQTS 520
A LS L +F + A + +++ LV D+G PPR +
Sbjct: 597 QNAWLSYQLLKATEPGLFGVWAHNGEVRTARLLSERDAAKHRLVVLVKDNGEPPRSAT 654
Score = 37.5 bits (83), Expect = 0.21
Identities = 59/279 (21%), Positives = 104/279 (37%), Gaps = 22/279 (7%)
Query: 226 DDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLIAE- 284
++ E+G+F+ + A+ +L S D+KQ ++++ TG + ++L E
Sbjct: 36 EETEKGSFVVNLAKDLGLAEGELAARGTRVVSD--DNKQYLLLDSHTGNLLTNEKLDREK 93
Query: 285 -LDPSVTIVLK-ATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGAS 342
P +L +D+P + A L F K+ +SE +
Sbjct: 94 LCGPKEPCMLYFQILMDDPFQIYRAELRVRDINDHSPV-------FRHKEMVLKISENTA 146
Query: 343 PGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLD-KFAINNAG----EVILRRSLDYETTS 397
G+ L E S + +S SF K + ++ G E++L ++LD E
Sbjct: 147 EGTAF-RLERAQDPDEGHNSIQNYTISSNSFFHIKISGSDEGMIYPELVLDKALDREEQE 205
Query: 398 NYFYQVMVTDSIS---NDTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXX 454
+ D S + T++I I V DVN+ P+F YE +
Sbjct: 206 ELSLTLTALDGGSPSRSGTSTIRIVVLDVNDNAPQFAQALYETQAPENSPVGSLIVKVSA 265
Query: 455 XXXXVAHDGDAGTLALSLAGQHARMFYINA-SGDLFLRE 492
+ + + F IN SG++FLRE
Sbjct: 266 GDADSGVNAEVSYSFFDASEDILTTFQINPFSGEIFLRE 304
>AF152502-1|AAD43763.2| 797|Homo sapiens protocadherin beta 9
protein.
Length = 797
Score = 98.3 bits (234), Expect = 1e-19
Identities = 97/392 (24%), Positives = 165/392 (42%), Gaps = 30/392 (7%)
Query: 56 NLTLLRALDREEKIGPSN---VYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAP 112
NL LDRE+ GP +Y + D DP + +RV D+ND++P +
Sbjct: 83 NLLTNEKLDREKLCGPKEPCMLYFQILMD-----DPFQIYRAELRVRDINDHSPVFRHKE 137
Query: 113 YAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGP--HSEYLGF-ENELEPIIVV 169
+++SE D D+ G +S +Y + H + G E + P +V+
Sbjct: 138 MVLKISENTAEGTAFRLERAQDPDE-GHNSIQNYTISSNSFFHIKISGSDEGMIYPELVL 196
Query: 170 KKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAE 229
K LD E ++ L D GSP +T+++ VLD +D P+F Y P+++
Sbjct: 197 DKALDREEQEELSLTLTALDGGSPSRSGTSTIRIVVLDVNDNAPQFAQALYETQAPENSP 256
Query: 230 EGTFLTTSPGPISAADQDLGINAPLQYS---STGDHKQLIVVNKDTGQVAATKQLIAELD 286
G+ + +SA D D G+NA + YS ++ D +N +G++ + L EL
Sbjct: 257 VGSLIV----KVSAGDADSGVNAEVSYSFFDASEDILTTFQINPFSGEIFLRELLDYELV 312
Query: 287 PSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSV 346
S I ++A +D A T+ + S +V+E SPG V
Sbjct: 313 NSYKINIQA--MDGGGLSARCTVLIKVLDSNDNPP-----ELIISSLSNSVAEN-SPGIV 364
Query: 347 LLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVT 406
L +++ + + + F K +++N ++ +LD E+ + Y + VT
Sbjct: 365 LAVFKIKDRDSGENGKTICYVQDNLPFFLKPSVDNFYILMTEGALDRESKAEYNITITVT 424
Query: 407 DSIS---NDTASINISVEDVNEWEPRFRHPQY 435
D + SI + V DVN+ P F Y
Sbjct: 425 DLGTPRLKTEHSITLQVSDVNDNAPAFTQTSY 456
Score = 81.0 bits (191), Expect = 2e-14
Identities = 90/316 (28%), Positives = 136/316 (43%), Gaps = 30/316 (9%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLR---ALDREE 67
++E++P G ++ + S + G +Q+ + P N +L ALDRE
Sbjct: 356 VAENSP-GIVLAVFKIKDRDSGENGKTICYVQDN-LPFFLKPSVDNFYILMTEGALDRES 413
Query: 68 KIGPSNVYVNVRC--DRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXX 125
K N+ + V R T+ S + VS DVNDNAP + Y + V E
Sbjct: 414 K-AEYNITITVTDLGTPRLKTEHSITLQVS----DVNDNAPAFTQTSYTLFVRENNSPAL 468
Query: 126 XXXXXXXSDRDQPGPHSALHYAVLP--GPHSEYLGFE--NELEPIIVVKKPLDFETVNNF 181
+DRD G ++ + Y++LP PH N + + LD+E + F
Sbjct: 469 HIGSVSATDRDS-GTNAQVTYSLLPPQDPHLPLASLVSINADNGHLFALRSLDYEALQAF 527
Query: 182 TIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTY------EHYTALLPDDAEEGTFLT 235
++ D+GSP L S+ ++V VLDA+D +P Y T L+P AE G +T
Sbjct: 528 DFRVGASDRGSPALSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVT 587
Query: 236 TSPGPISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPSV-TIVL 293
+ A D D G NA L Y L V G+V T +L++E D + +V+
Sbjct: 588 ----KVVAVDGDSGQNAWLSYQLLKATEPGLFGVWAHNGEV-RTARLLSERDAAKHRLVV 642
Query: 294 KATQVDNPDRYALATL 309
P R A ATL
Sbjct: 643 LVKDNGEPPRSATATL 658
Score = 70.5 bits (165), Expect = 2e-11
Identities = 110/478 (23%), Positives = 175/478 (36%), Gaps = 30/478 (6%)
Query: 57 LTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVR 116
L L +ALDREE+ + + + + S + + V DVNDNAPQ+ A Y +
Sbjct: 194 LVLDKALDREEQ---EELSLTLTALDGGSPSRSGTSTIRIVVLDVNDNAPQFAQALYETQ 250
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFE-NELEPIIVVKKPLDF 175
E D D G ++ + Y+ F+ N I +++ LD+
Sbjct: 251 APENSPVGSLIVKVSAGDADS-GVNAEVSYSFFDASEDILTTFQINPFSGEIFLRELLDY 309
Query: 176 ETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLT 235
E VN++ I ++ D G L + T+ + VLD++D P+ + + +++ G L
Sbjct: 310 ELVNSYKINIQAMDGGG--LSARCTVLIKVLDSNDNPPELIISSLSNSVAENSP-GIVLA 366
Query: 236 TSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATK-QLIAELDPSVTIVLK 294
D+D G N + + + D + T+ L E I +
Sbjct: 367 V----FKIKDRDSGENGKTICYVQDNLPFFLKPSVDNFYILMTEGALDRESKAEYNITIT 422
Query: 295 ATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASP----GSVLLTL 350
T + P L T FTQ Y+ V E SP GSV T
Sbjct: 423 VTDLGTP---RLKTEHSITLQVSDVNDNAPA--FTQTSYTLFVRENNSPALHIGSVSATD 477
Query: 351 TTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTDSI 409
N + S L +IN + G + RSLDYE + ++V +D
Sbjct: 478 RDSGTNAQVTYSLLPPQDPHLPLASLVSINADNGHLFALRSLDYEALQAFDFRVGASDRG 537
Query: 410 S---NDTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGDAG 466
S + A + + V D N+ P +P VA DGD+G
Sbjct: 538 SPALSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVTKVVAVDGDSG 597
Query: 467 TLA-LS---LAGQHARMFYINASGDLFLREEAIGNLNSSSLHLVATAIDSGIPPRQTS 520
A LS L +F + A + +++ LV D+G PPR +
Sbjct: 598 QNAWLSYQLLKATEPGLFGVWAHNGEVRTARLLSERDAAKHRLVVLVKDNGEPPRSAT 655
Score = 37.5 bits (83), Expect = 0.21
Identities = 59/279 (21%), Positives = 104/279 (37%), Gaps = 22/279 (7%)
Query: 226 DDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLIAE- 284
++ E+G+F+ + A+ +L S D+KQ ++++ TG + ++L E
Sbjct: 37 EETEKGSFVVNLAKDLGLAEGELAARGTRVVSD--DNKQYLLLDSHTGNLLTNEKLDREK 94
Query: 285 -LDPSVTIVLK-ATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGAS 342
P +L +D+P + A L F K+ +SE +
Sbjct: 95 LCGPKEPCMLYFQILMDDPFQIYRAELRVRDINDHSPV-------FRHKEMVLKISENTA 147
Query: 343 PGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLD-KFAINNAG----EVILRRSLDYETTS 397
G+ L E S + +S SF K + ++ G E++L ++LD E
Sbjct: 148 EGTAF-RLERAQDPDEGHNSIQNYTISSNSFFHIKISGSDEGMIYPELVLDKALDREEQE 206
Query: 398 NYFYQVMVTDSIS---NDTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXX 454
+ D S + T++I I V DVN+ P+F YE +
Sbjct: 207 ELSLTLTALDGGSPSRSGTSTIRIVVLDVNDNAPQFAQALYETQAPENSPVGSLIVKVSA 266
Query: 455 XXXXVAHDGDAGTLALSLAGQHARMFYINA-SGDLFLRE 492
+ + + F IN SG++FLRE
Sbjct: 267 GDADSGVNAEVSYSFFDASEDILTTFQINPFSGEIFLRE 305
>BC105636-1|AAI05637.1| 797|Homo sapiens protocadherin beta 9
protein.
Length = 797
Score = 97.9 bits (233), Expect = 1e-19
Identities = 97/392 (24%), Positives = 165/392 (42%), Gaps = 30/392 (7%)
Query: 56 NLTLLRALDREEKIGPSN---VYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAP 112
NL LDRE+ GP +Y + D DP + +RV D+ND++P +
Sbjct: 83 NLLTNEKLDREKLCGPKEPCMLYFQILMD-----DPFQIYRAELRVRDINDHSPVFRHKE 137
Query: 113 YAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGP--HSEYLGF-ENELEPIIVV 169
+++SE D D+ G +S +Y + H + G E + P +V+
Sbjct: 138 MVLKISENTAEGTAFRLERAQDPDE-GHNSIQNYTISSNSFFHIKISGSDEGMIYPELVL 196
Query: 170 KKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAE 229
K LD E ++ L D GSP +T+++ VLD +D P+F Y P+++
Sbjct: 197 DKALDREEQEELSLTLTALDGGSPSRSGTSTIRIVVLDVNDNVPQFAQALYETQAPENSP 256
Query: 230 EGTFLTTSPGPISAADQDLGINAPLQYS---STGDHKQLIVVNKDTGQVAATKQLIAELD 286
G+ + +SA D D G+NA + YS ++ D +N +G++ + L EL
Sbjct: 257 VGSLIV----KVSAGDADSGVNAEVSYSFFDASEDILTTFQINPFSGEIFLRELLDYELV 312
Query: 287 PSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSV 346
S I ++A +D A T+ + S +V+E SPG V
Sbjct: 313 NSYKINIQA--MDGGGLSARCTVLIKVLDSNDNPP-----ELIISSLSNSVAEN-SPGIV 364
Query: 347 LLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVT 406
L +++ + + + F K +++N ++ +LD E+ + Y + VT
Sbjct: 365 LAVFKIKDRDSGENGKTICYVQDNLPFFLKPSVDNFYILMTEGALDRESKAEYNITITVT 424
Query: 407 DSIS---NDTASINISVEDVNEWEPRFRHPQY 435
D + SI + V DVN+ P F Y
Sbjct: 425 DLGTPRLKTEHSITLQVSDVNDNAPAFTQTSY 456
Score = 81.0 bits (191), Expect = 2e-14
Identities = 90/316 (28%), Positives = 136/316 (43%), Gaps = 30/316 (9%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLR---ALDREE 67
++E++P G ++ + S + G +Q+ + P N +L ALDRE
Sbjct: 356 VAENSP-GIVLAVFKIKDRDSGENGKTICYVQDN-LPFFLKPSVDNFYILMTEGALDRES 413
Query: 68 KIGPSNVYVNVRC--DRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXX 125
K N+ + V R T+ S + VS DVNDNAP + Y + V E
Sbjct: 414 K-AEYNITITVTDLGTPRLKTEHSITLQVS----DVNDNAPAFTQTSYTLFVRENNSPAL 468
Query: 126 XXXXXXXSDRDQPGPHSALHYAVLP--GPHSEYLGFE--NELEPIIVVKKPLDFETVNNF 181
+DRD G ++ + Y++LP PH N + + LD+E + F
Sbjct: 469 HIGSVSATDRDS-GTNAQVTYSLLPPQDPHLPLASLVSINADNGHLFALRSLDYEALQAF 527
Query: 182 TIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTY------EHYTALLPDDAEEGTFLT 235
++ D+GSP L S+ ++V VLDA+D +P Y T L+P AE G +T
Sbjct: 528 DFRVGASDRGSPALSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVT 587
Query: 236 TSPGPISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPSV-TIVL 293
+ A D D G NA L Y L V G+V T +L++E D + +V+
Sbjct: 588 ----KVVAVDGDSGQNAWLSYQLLKATEPGLFGVWAHNGEV-RTARLLSERDAAKHRLVV 642
Query: 294 KATQVDNPDRYALATL 309
P R A ATL
Sbjct: 643 LVKDNGEPPRSATATL 658
Score = 68.9 bits (161), Expect = 7e-11
Identities = 109/478 (22%), Positives = 174/478 (36%), Gaps = 30/478 (6%)
Query: 57 LTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVR 116
L L +ALDREE+ + + + + S + + V DVNDN PQ+ A Y +
Sbjct: 194 LVLDKALDREEQ---EELSLTLTALDGGSPSRSGTSTIRIVVLDVNDNVPQFAQALYETQ 250
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFE-NELEPIIVVKKPLDF 175
E D D G ++ + Y+ F+ N I +++ LD+
Sbjct: 251 APENSPVGSLIVKVSAGDADS-GVNAEVSYSFFDASEDILTTFQINPFSGEIFLRELLDY 309
Query: 176 ETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLT 235
E VN++ I ++ D G L + T+ + VLD++D P+ + + +++ G L
Sbjct: 310 ELVNSYKINIQAMDGGG--LSARCTVLIKVLDSNDNPPELIISSLSNSVAENSP-GIVLA 366
Query: 236 TSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATK-QLIAELDPSVTIVLK 294
D+D G N + + + D + T+ L E I +
Sbjct: 367 V----FKIKDRDSGENGKTICYVQDNLPFFLKPSVDNFYILMTEGALDRESKAEYNITIT 422
Query: 295 ATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASP----GSVLLTL 350
T + P L T FTQ Y+ V E SP GSV T
Sbjct: 423 VTDLGTP---RLKTEHSITLQVSDVNDNAPA--FTQTSYTLFVRENNSPALHIGSVSATD 477
Query: 351 TTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTDSI 409
N + S L +IN + G + RSLDYE + ++V +D
Sbjct: 478 RDSGTNAQVTYSLLPPQDPHLPLASLVSINADNGHLFALRSLDYEALQAFDFRVGASDRG 537
Query: 410 S---NDTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGDAG 466
S + A + + V D N+ P +P VA DGD+G
Sbjct: 538 SPALSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVTKVVAVDGDSG 597
Query: 467 TLA-LS---LAGQHARMFYINASGDLFLREEAIGNLNSSSLHLVATAIDSGIPPRQTS 520
A LS L +F + A + +++ LV D+G PPR +
Sbjct: 598 QNAWLSYQLLKATEPGLFGVWAHNGEVRTARLLSERDAAKHRLVVLVKDNGEPPRSAT 655
Score = 37.1 bits (82), Expect = 0.28
Identities = 59/279 (21%), Positives = 104/279 (37%), Gaps = 22/279 (7%)
Query: 226 DDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLIAE- 284
++ E+G+F+ + A+ +L S D+KQ ++++ TG + ++L E
Sbjct: 37 EETEKGSFVVNLAKDLGLAEGELAARGTRVVSD--DNKQYLLLDSHTGNLLTNEKLDREK 94
Query: 285 -LDPSVTIVLK-ATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGAS 342
P +L +D+P + A L F K+ +SE +
Sbjct: 95 LCGPKEPCMLYFQILMDDPFQIYRAELRVRDINDHSPV-------FRHKEMVLKISENTA 147
Query: 343 PGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLD-KFAINNAG----EVILRRSLDYETTS 397
G+ L E S + +S SF K + ++ G E++L ++LD E
Sbjct: 148 EGTAF-RLERAQDPDEGHNSIQNYTISSNSFFHIKISGSDEGMIYPELVLDKALDREEQE 206
Query: 398 NYFYQVMVTDSIS---NDTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXX 454
+ D S + T++I I V DVN+ P+F YE +
Sbjct: 207 ELSLTLTALDGGSPSRSGTSTIRIVVLDVNDNVPQFAQALYETQAPENSPVGSLIVKVSA 266
Query: 455 XXXXVAHDGDAGTLALSLAGQHARMFYINA-SGDLFLRE 492
+ + + F IN SG++FLRE
Sbjct: 267 GDADSGVNAEVSYSFFDASEDILTTFQINPFSGEIFLRE 305
>BC100672-1|AAI00673.1| 797|Homo sapiens protocadherin beta 9
protein.
Length = 797
Score = 97.9 bits (233), Expect = 1e-19
Identities = 97/392 (24%), Positives = 165/392 (42%), Gaps = 30/392 (7%)
Query: 56 NLTLLRALDREEKIGPSN---VYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAP 112
NL LDRE+ GP +Y + D DP + +RV D+ND++P +
Sbjct: 83 NLLTNEKLDREKLCGPKEPCMLYFQILMD-----DPFQIYRAELRVRDINDHSPVFRHKE 137
Query: 113 YAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGP--HSEYLGF-ENELEPIIVV 169
+++SE D D+ G +S +Y + H + G E + P +V+
Sbjct: 138 MVLKISENTAEGTAFRLERAQDPDE-GHNSIQNYTISSNSFFHIKISGSDEGMIYPELVL 196
Query: 170 KKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAE 229
K LD E ++ L D GSP +T+++ VLD +D P+F Y P+++
Sbjct: 197 DKALDREEQEELSLTLTALDGGSPSRSGTSTIRIVVLDVNDNVPQFAQALYETQAPENSP 256
Query: 230 EGTFLTTSPGPISAADQDLGINAPLQYS---STGDHKQLIVVNKDTGQVAATKQLIAELD 286
G+ + +SA D D G+NA + YS ++ D +N +G++ + L EL
Sbjct: 257 VGSLIV----KVSAGDADSGVNAEVSYSFFDASEDILTTFQINPFSGEIFLRELLDYELV 312
Query: 287 PSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSV 346
S I ++A +D A T+ + S +V+E SPG V
Sbjct: 313 NSYKINIQA--MDGGGLSARCTVLIKVLDSNDNPP-----ELIISSLSNSVAEN-SPGIV 364
Query: 347 LLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVT 406
L +++ + + + F K +++N ++ +LD E+ + Y + VT
Sbjct: 365 LAVFKIKDRDSGENGKTICYVQDNLPFFLKPSVDNFYILMTEGALDRESKAEYNITITVT 424
Query: 407 DSIS---NDTASINISVEDVNEWEPRFRHPQY 435
D + SI + V DVN+ P F Y
Sbjct: 425 DLGTPRLKTEHSITLQVSDVNDNAPAFTQTSY 456
Score = 81.0 bits (191), Expect = 2e-14
Identities = 90/316 (28%), Positives = 136/316 (43%), Gaps = 30/316 (9%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLR---ALDREE 67
++E++P G ++ + S + G +Q+ + P N +L ALDRE
Sbjct: 356 VAENSP-GIVLAVFKIKDRDSGENGKTICYVQDN-LPFFLKPSVDNFYILMTEGALDRES 413
Query: 68 KIGPSNVYVNVRC--DRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXX 125
K N+ + V R T+ S + VS DVNDNAP + Y + V E
Sbjct: 414 K-AEYNITITVTDLGTPRLKTEHSITLQVS----DVNDNAPAFTQTSYTLFVRENNSPAL 468
Query: 126 XXXXXXXSDRDQPGPHSALHYAVLP--GPHSEYLGFE--NELEPIIVVKKPLDFETVNNF 181
+DRD G ++ + Y++LP PH N + + LD+E + F
Sbjct: 469 HIGSVSATDRDS-GTNAQVTYSLLPPQDPHLPLASLVSINADNGHLFALRSLDYEALQAF 527
Query: 182 TIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTY------EHYTALLPDDAEEGTFLT 235
++ D+GSP L S+ ++V VLDA+D +P Y T L+P AE G +T
Sbjct: 528 DFRVGASDRGSPALSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVT 587
Query: 236 TSPGPISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPSV-TIVL 293
+ A D D G NA L Y L V G+V T +L++E D + +V+
Sbjct: 588 ----KVVAVDGDSGQNAWLSYQLLKATEPGLFGVWAHNGEV-RTARLLSERDAAKHRLVV 642
Query: 294 KATQVDNPDRYALATL 309
P R A ATL
Sbjct: 643 LVKDNGEPPRSATATL 658
Score = 68.9 bits (161), Expect = 7e-11
Identities = 109/478 (22%), Positives = 174/478 (36%), Gaps = 30/478 (6%)
Query: 57 LTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVR 116
L L +ALDREE+ + + + + S + + V DVNDN PQ+ A Y +
Sbjct: 194 LVLDKALDREEQ---EELSLTLTALDGGSPSRSGTSTIRIVVLDVNDNVPQFAQALYETQ 250
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFE-NELEPIIVVKKPLDF 175
E D D G ++ + Y+ F+ N I +++ LD+
Sbjct: 251 APENSPVGSLIVKVSAGDADS-GVNAEVSYSFFDASEDILTTFQINPFSGEIFLRELLDY 309
Query: 176 ETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLT 235
E VN++ I ++ D G L + T+ + VLD++D P+ + + +++ G L
Sbjct: 310 ELVNSYKINIQAMDGGG--LSARCTVLIKVLDSNDNPPELIISSLSNSVAENSP-GIVLA 366
Query: 236 TSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATK-QLIAELDPSVTIVLK 294
D+D G N + + + D + T+ L E I +
Sbjct: 367 V----FKIKDRDSGENGKTICYVQDNLPFFLKPSVDNFYILMTEGALDRESKAEYNITIT 422
Query: 295 ATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASP----GSVLLTL 350
T + P L T FTQ Y+ V E SP GSV T
Sbjct: 423 VTDLGTP---RLKTEHSITLQVSDVNDNAPA--FTQTSYTLFVRENNSPALHIGSVSATD 477
Query: 351 TTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTDSI 409
N + S L +IN + G + RSLDYE + ++V +D
Sbjct: 478 RDSGTNAQVTYSLLPPQDPHLPLASLVSINADNGHLFALRSLDYEALQAFDFRVGASDRG 537
Query: 410 S---NDTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGDAG 466
S + A + + V D N+ P +P VA DGD+G
Sbjct: 538 SPALSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVTKVVAVDGDSG 597
Query: 467 TLA-LS---LAGQHARMFYINASGDLFLREEAIGNLNSSSLHLVATAIDSGIPPRQTS 520
A LS L +F + A + +++ LV D+G PPR +
Sbjct: 598 QNAWLSYQLLKATEPGLFGVWAHNGEVRTARLLSERDAAKHRLVVLVKDNGEPPRSAT 655
Score = 37.1 bits (82), Expect = 0.28
Identities = 59/279 (21%), Positives = 104/279 (37%), Gaps = 22/279 (7%)
Query: 226 DDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLIAE- 284
++ E+G+F+ + A+ +L S D+KQ ++++ TG + ++L E
Sbjct: 37 EETEKGSFVVNLAKDLGLAEGELAARGTRVVSD--DNKQYLLLDSHTGNLLTNEKLDREK 94
Query: 285 -LDPSVTIVLK-ATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGAS 342
P +L +D+P + A L F K+ +SE +
Sbjct: 95 LCGPKEPCMLYFQILMDDPFQIYRAELRVRDINDHSPV-------FRHKEMVLKISENTA 147
Query: 343 PGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLD-KFAINNAG----EVILRRSLDYETTS 397
G+ L E S + +S SF K + ++ G E++L ++LD E
Sbjct: 148 EGTAF-RLERAQDPDEGHNSIQNYTISSNSFFHIKISGSDEGMIYPELVLDKALDREEQE 206
Query: 398 NYFYQVMVTDSIS---NDTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXX 454
+ D S + T++I I V DVN+ P+F YE +
Sbjct: 207 ELSLTLTALDGGSPSRSGTSTIRIVVLDVNDNVPQFAQALYETQAPENSPVGSLIVKVSA 266
Query: 455 XXXXVAHDGDAGTLALSLAGQHARMFYINA-SGDLFLRE 492
+ + + F IN SG++FLRE
Sbjct: 267 GDADSGVNAEVSYSFFDASEDILTTFQINPFSGEIFLRE 305
>BC045637-1|AAH45637.1| 795|Homo sapiens protocadherin beta 12
protein.
Length = 795
Score = 97.9 bits (233), Expect = 1e-19
Identities = 101/448 (22%), Positives = 188/448 (41%), Gaps = 33/448 (7%)
Query: 3 GGAVESFFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRL--QEKGAAVGIVPGSKNLTL 59
G +F + E+ GS +G L+ G +L R+ + + + + +L L
Sbjct: 27 GSETGNFLVMEELQSGSFVGNLAKTLGLEVSELSSRGARVVSNDNKECLQLDTNTGDLLL 86
Query: 60 LRALDREEKIG---PSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVR 116
LDREE G P +Y V +P+ + + ++V D+ND++P + +
Sbjct: 87 REMLDREELCGSNEPCVLYFQVLMK-----NPTQFLQIELQVRDINDHSPVFLEKEMLLE 141
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEY---LGFENELEPIIVVKKPL 173
+ E D D G ++ Y + P H + +N P +V+ K L
Sbjct: 142 IPENSPVGAVFLLESAKDLDV-GINAVKSYTINPNSHFHVKIRVNPDNRKYPELVLDKAL 200
Query: 174 DFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTF 233
D+E + L D GSPP ++V V+D +D +P+F Y + +++ G+
Sbjct: 201 DYEERPELSFILTALDGGSPPRSGTALVRVVVVDINDNSPEFEQAFYEVKILENSILGSL 260
Query: 234 LTTSPGPISAADQDLGINAPLQYS---STGDHKQLIVVNKDTGQVAATKQLIAELDPSVT 290
+ T +SA D D G N+ L Y+ ++ D ++ +N+ +G + T L E S +
Sbjct: 261 VVT----VSAWDLDSGTNSELSYTFSHASEDIRKTFEINQKSGDITLTAPLDFEAIESYS 316
Query: 291 IVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTL 350
I+++AT D + +T+ + T ++ + E +P +V++
Sbjct: 317 IIIQAT--DGGGLFGKSTVRIQVMDVNDNAP-----EITVSSITSPIPEN-TPETVVMVF 368
Query: 351 TTVPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSIS 410
+++ + D F+ K ++NN + R LD E+ + Y + VTD +
Sbjct: 369 RIRDRDSGDNGKMVCSIPEDIPFVLKSSVNNYYTLETERPLDRESRAEYNITITVTDLGT 428
Query: 411 ---NDTASINISVEDVNEWEPRFRHPQY 435
+I + V DVN+ P F Y
Sbjct: 429 PRLKTEHNITVLVSDVNDNAPAFTQTSY 456
Score = 91.9 bits (218), Expect = 9e-18
Identities = 116/478 (24%), Positives = 182/478 (38%), Gaps = 30/478 (6%)
Query: 57 LTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVR 116
L L +ALD EE+ P ++ D + V V V D+NDN+P++E A Y V+
Sbjct: 194 LVLDKALDYEER--PELSFILTALDGGSPPRSGTAL-VRVVVVDINDNSPEFEQAFYEVK 250
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFE-NELEPIIVVKKPLDF 175
+ E D D G +S L Y FE N+ I + PLDF
Sbjct: 251 ILENSILGSLVVTVSAWDLDS-GTNSELSYTFSHASEDIRKTFEINQKSGDITLTAPLDF 309
Query: 176 ETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLT 235
E + +++I ++ D G L+ +T+++ V+D +D P+ T T+ +P++ E +
Sbjct: 310 EAIESYSIIIQATDGGG--LFGKSTVRIQVMDVNDNAPEITVSSITSPIPENTPETVVMV 367
Query: 236 TSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQ-LIAELDPSVTIVLK 294
D+D G N + S D ++ + + T++ L E I +
Sbjct: 368 -----FRIRDRDSGDNGKMVCSIPEDIPFVLKSSVNNYYTLETERPLDRESRAEYNITIT 422
Query: 295 ATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASP----GSVLLTL 350
T + P L T FTQ Y+ V E SP GS+ T
Sbjct: 423 VTDLGTP---RLKTEHNITVLVSDVNDNAPA--FTQTSYALFVRENNSPALHIGSISATD 477
Query: 351 TTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTDSI 409
N + S L +IN + G + RSLDYE + ++V TD
Sbjct: 478 RDSGTNAQVNYSLLPSQDPHLPLASLVSINADNGHLFALRSLDYEALQGFQFRVGATDHG 537
Query: 410 S---NDTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGDAG 466
S + A + + V D N+ P +P VA DGD+G
Sbjct: 538 SPALSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPWAAEPGYLVTKVVAVDGDSG 597
Query: 467 TLA-LS---LAGQHARMFYINASGDLFLREEAIGNLNSSSLHLVATAIDSGIPPRQTS 520
A LS L +F + A + +++ LV D+G PPR +
Sbjct: 598 QNAWLSYQLLKATEPGLFGVWAHNGEVRTARLLSERDAAKHRLVVLVKDNGEPPRSAT 655
Score = 79.8 bits (188), Expect = 4e-14
Identities = 91/315 (28%), Positives = 134/315 (42%), Gaps = 28/315 (8%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAV--GIVPGSKNLTLLRALDREEK 68
I E+TP +++ + S D G + + E V V L R LDRE +
Sbjct: 356 IPENTP-ETVVMVFRIRDRDSGDNGKMVCSIPEDIPFVLKSSVNNYYTLETERPLDRESR 414
Query: 69 IGPSNVYVNVRC--DRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXX 126
N+ + V R T+ + + VS DVNDNAP + YA+ V E
Sbjct: 415 -AEYNITITVTDLGTPRLKTEHNITVLVS----DVNDNAPAFTQTSYALFVRENNSPALH 469
Query: 127 XXXXXXSDRDQPGPHSALHYAVLPG--PHSEYLGFE--NELEPIIVVKKPLDFETVNNFT 182
+DRD G ++ ++Y++LP PH N + + LD+E + F
Sbjct: 470 IGSISATDRDS-GTNAQVNYSLLPSQDPHLPLASLVSINADNGHLFALRSLDYEALQGFQ 528
Query: 183 IKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTY------EHYTALLPDDAEEGTFLTT 236
++ D GSP L S+ ++V VLDA+D +P Y T L+P AE G +T
Sbjct: 529 FRVGATDHGSPALSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPWAAEPGYLVT- 587
Query: 237 SPGPISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPSV-TIVLK 294
+ A D D G NA L Y L V G+V T +L++E D + +V+
Sbjct: 588 ---KVVAVDGDSGQNAWLSYQLLKATEPGLFGVWAHNGEV-RTARLLSERDAAKHRLVVL 643
Query: 295 ATQVDNPDRYALATL 309
P R A ATL
Sbjct: 644 VKDNGEPPRSATATL 658
>BC000059-1|AAH00059.2| 771|Homo sapiens CELSR1 protein protein.
Length = 771
Score = 97.9 bits (233), Expect = 1e-19
Identities = 99/418 (23%), Positives = 164/418 (39%), Gaps = 18/418 (4%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEKIG 70
+SED P+G+ I TLS N + + + IT +Q+ I P S + + LD E ++
Sbjct: 172 VSEDRPVGTSIATLSANDEDTGENARITYVIQDPVPQFRIDPDSGTMYTMMELDYENQVA 231
Query: 71 PSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXX 130
+ + + S + + + D NDNAPQ+ Y + E
Sbjct: 232 YT---LTIMAQDNGIPQKSDTTTLEILILDANDNAPQFLWDFYQGSIFEDAPPSTSILQV 288
Query: 131 XXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQ 190
+DRD GP+ L Y G + + +I ++ LD E V + + D+
Sbjct: 289 SATDRDS-GPNGRLLYTFQGGDDGDGDFYIEPTSGVIRTQRRLDRENVAVYNLWALAVDR 347
Query: 191 GSP-PLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLG 249
GSP PL + +QVT+LD +D P F + + ++ G+ + I A D D G
Sbjct: 348 GSPTPLSASVEIQVTILDINDNAPMFEKDELELFVEENNPVGSVV----AKIRANDPDEG 403
Query: 250 INAPLQYSST-GDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALAT 308
NA + Y GD + ++ G + A +L E+ +V++AT R AT
Sbjct: 404 PNAQIMYQIVEGDMRHFFQLDLLNGDLRAMVELDFEVRREYVLVVQATSAPLVSR---AT 460
Query: 309 LXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYV 368
+ Q Y T S G + +P + L +
Sbjct: 461 VHILLVDQNDNPPVLPDFQILFNNYVTNKSNSFPTG----VIGRIPAHDPDVSDSLNYTF 516
Query: 369 SDRSFLDKFAINNA-GEVILRRSLDYETTSNYFYQVMVTDSISNDTASINISVEDVNE 425
+ L ++ A GE+ L R LD +V V+D I + TA + V + +
Sbjct: 517 VQGNELRLLLLDPATGELQLSRDLDNNRPLEALMEVSVSDGIHSVTAFCTLRVTIITD 574
Score = 83.4 bits (197), Expect = 3e-15
Identities = 86/365 (23%), Positives = 146/365 (40%), Gaps = 26/365 (7%)
Query: 167 IVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPD 226
I V LD E V++++ + D G PP+ S T++ +TVLD +D +P FT Y L +
Sbjct: 13 ITVCAELDREEVDHYSFGVEAVDHGWPPMSSSTSVSITVLDVNDNDPVFTQPTYELRLNE 72
Query: 227 DAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDH-KQLIVVNKDTGQVAATKQLIAEL 285
DA G+ + T + A D+D N+ + Y TG + + ++ G T L +
Sbjct: 73 DAAVGSSVLT----LQARDRD--ANSVITYQLTGGNTRNRFALSSQRGGGLITLALPLDY 126
Query: 286 DPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGS 345
VL T D + L F Y+ +VSE G+
Sbjct: 127 KQEQQYVLAVTASDGTRSHTAHVLINVTDANTHRPV------FQSSHYTVSVSEDRPVGT 180
Query: 346 VLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVM 404
+ TL+ ++T + + + + D + +F I+ ++G + LDYE Y +M
Sbjct: 181 SIATLSANDEDTG-ENARITYVIQDP--VPQFRIDPDSGTMYTMMELDYENQVAYTLTIM 237
Query: 405 VTDS---ISNDTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAH 461
D+ +DT ++ I + D N+ P+F ++F
Sbjct: 238 AQDNGIPQKSDTTTLEILILDANDNAPQF---LWDFYQGSIFEDAPPSTSILQVSATDRD 294
Query: 462 DGDAGTLALSLAG--QHARMFYINASGDLFLREEAIGNLNSSSLHLVATAIDSGIP-PRQ 518
G G L + G FYI + + + + N + +L A A+D G P P
Sbjct: 295 SGPNGRLLYTFQGGDDGDGDFYIEPTSGVIRTQRRLDRENVAVYNLWALAVDRGSPTPLS 354
Query: 519 TSVPV 523
SV +
Sbjct: 355 ASVEI 359
Score = 76.6 bits (180), Expect = 4e-13
Identities = 80/349 (22%), Positives = 139/349 (39%), Gaps = 22/349 (6%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
VS+ V DVNDN P + Y +R++E DRD +S + Y + G
Sbjct: 47 VSITVLDVNDNDPVFTQPTYELRLNEDAAVGSSVLTLQARDRD---ANSVITYQLTGGNT 103
Query: 154 SEYLGFENEL-EPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQN 212
++ +I + PLD++ + + + D G+ + + VT DA+
Sbjct: 104 RNRFALSSQRGGGLITLALPLDYKQEQQYVLAVTASD-GTRSHTAHVLINVT--DANTHR 160
Query: 213 PKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDT 272
P F HYT + +D GT + T +SA D+D G NA + Y D ++ D+
Sbjct: 161 PVFQSSHYTVSVSEDRPVGTSIAT----LSANDEDTGENARITY-VIQDPVPQFRIDPDS 215
Query: 273 GQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQ 332
G + +L E + T+ + A P + TL QF
Sbjct: 216 GTMYTMMELDYENQVAYTLTIMAQDNGIPQKSDTTTLEILILDANDNAP-----QFLWDF 270
Query: 333 YSTTVSEGASPGSVLLTLTTVPQNTEFRESPL-QFYVSDRSFLDKFAINNAGEVILRRSL 391
Y ++ E A P + +L ++ +++ L F D D + +G + +R L
Sbjct: 271 YQGSIFEDAPPSTSILQVSATDRDSGPNGRLLYTFQGGDDGDGDFYIEPTSGVIRTQRRL 330
Query: 392 DYETTSNYFYQVMVTDSIS----NDTASINISVEDVNEWEPRFRHPQYE 436
D E + Y + D S + + I +++ D+N+ P F + E
Sbjct: 331 DRENVAVYNLWALAVDRGSPTPLSASVEIQVTILDINDNAPMFEKDELE 379
>AL031687-1|CAB51587.2| 828|Homo sapiens cadherin-like 22 protein.
Length = 828
Score = 97.9 bits (233), Expect = 1e-19
Identities = 108/456 (23%), Positives = 188/456 (41%), Gaps = 36/456 (7%)
Query: 3 GGAVESFFISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPG--SKNLTLL 60
G FF+ E+ + ++ D E G I + +GA + + ++ +
Sbjct: 63 GWVWNQFFVVEEYTGTEPLYVGKIHSDSDEGDGAIKYTISGEGAGTIFLIDELTGDIHAM 122
Query: 61 RALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVS---VRVWDVNDNAPQWEGAPYAVRV 117
LDRE+K + +R R + P S ++V D+ND+ P++ PY V
Sbjct: 123 ERLDREQK-----TFYTLRAQARDRATNRLLEPESEFIIKVQDINDSEPRFLHGPYIGSV 177
Query: 118 SETXXXXXXXXXXXXSDRDQP--GPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDF 175
+E SD D P G + L Y+VL G H + + + I LD
Sbjct: 178 AELSPTGTSVMQVMASDADDPTYGSSARLVYSVLDGEH--HFTVDPKTGVIRTAVPDLDR 235
Query: 176 ETVNNFTIKLRVQDQGSP--PLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTF 233
E+ + + ++ D L TT+ + V D +D P+F + Y + + A G
Sbjct: 236 ESQERYEVVIQATDMAGQLGGLSGSTTVTIVVTDVNDNPPRFPQKMYQFSIQESAPIG-- 293
Query: 234 LTTSPGPISAADQDLGINAPLQY-----SSTGDHKQLIVVNKDTGQ--VAATKQLIAELD 286
T+ G + A D D+G N + Y SS+G + + DT + + K+L E
Sbjct: 294 --TAVGRVKAEDSDVGENTDMTYHLKDESSSGGDVFKVTTDSDTQEAIIVVQKRLDFESQ 351
Query: 287 PSVTIVLKATQVDNPDRYA-LATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGS 345
P T++L+A R+A L T +F V E A GS
Sbjct: 352 PVHTVILEALNKFVDPRFADLGTFRDQAIVRVAVTDVDEPPEFRPPSGLLEVQEDAQVGS 411
Query: 346 VLLTLTTVPQNTEFRESPLQFYVSDRSFLDK-FAIN-NAGEVILRRSLDYETTSNYFYQV 403
++ +T ++ + P+++ + S LD+ F I+ + G ++ + LD ET + V
Sbjct: 412 LVGVVTA--RDPDAANRPVRYAIDRESDLDQIFDIDADTGAIVTGKGLDRETAGWHNITV 469
Query: 404 MVTDSISN---DTASINISVEDVNEWEPRFRHPQYE 436
+ ++ ++ AS+ I + DVN+ P P YE
Sbjct: 470 LAMEADNHAQLSRASLRIRILDVNDNPPELATP-YE 504
Score = 46.0 bits (104), Expect = 6e-04
Identities = 42/206 (20%), Positives = 77/206 (37%), Gaps = 12/206 (5%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKG---AAVGIVPGSKNLTLLRALDREE 67
+ ED +GS++G ++ DP + + + I + + + LDRE
Sbjct: 403 VQEDAQVGSLVGVVTAR-DPDAANRPVRYAIDRESDLDQIFDIDADTGAIVTGKGLDRET 461
Query: 68 KIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXX 127
+ + + D + + +R+ DVNDN P+ PY V E
Sbjct: 462 AGWHNITVLAMEADNHAQLSRA---SLRIRILDVNDNPPEL-ATPYEAAVCEDAKPGQLI 517
Query: 128 XXXXXSDRDQPGPHSALHYAVLP----GPHSEYLGFENELEPIIVVKKPLDFETVNNFTI 183
DRD+P ++ ++P PH L ++ + + + + F +
Sbjct: 518 QTISVVDRDEPQGGHRFYFRLVPEAPSNPHFSLLDIQDNTAAVHTQHVGFNRQEQDVFFL 577
Query: 184 KLRVQDQGSPPLYSDTTLQVTVLDAD 209
+ V D G P L S TL + + D
Sbjct: 578 PILVVDSGPPTLSSTGTLTIRICGCD 603
>AF217746-1|AAK51614.1| 795|Homo sapiens protocadherin-beta12
protein.
Length = 795
Score = 97.9 bits (233), Expect = 1e-19
Identities = 101/448 (22%), Positives = 188/448 (41%), Gaps = 33/448 (7%)
Query: 3 GGAVESFFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRL--QEKGAAVGIVPGSKNLTL 59
G +F + E+ GS +G L+ G +L R+ + + + + +L L
Sbjct: 27 GSETGNFLVMEELQSGSFVGNLAKTLGLEVSELSSRGARVVSNDNKECLQLDTNTGDLLL 86
Query: 60 LRALDREEKIG---PSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVR 116
LDREE G P +Y V +P+ + + ++V D+ND++P + +
Sbjct: 87 REMLDREELCGSNEPCVLYFQVLMK-----NPTQFLQIELQVRDINDHSPVFLEKEMLLE 141
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEY---LGFENELEPIIVVKKPL 173
+ E D D G ++ Y + P H + +N P +V+ K L
Sbjct: 142 IPENSPVGAVFLLESAKDLDV-GINAVKSYTINPNSHFHVKIRVNPDNRKYPELVLDKAL 200
Query: 174 DFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTF 233
D+E + L D GSPP ++V V+D +D +P+F Y + +++ G+
Sbjct: 201 DYEERPELSFILTALDGGSPPRSGTALVRVVVVDINDNSPEFEQAFYEVKILENSILGSL 260
Query: 234 LTTSPGPISAADQDLGINAPLQYS---STGDHKQLIVVNKDTGQVAATKQLIAELDPSVT 290
+ T +SA D D G N+ L Y+ ++ D ++ +N+ +G + T L E S +
Sbjct: 261 VVT----VSAWDLDSGTNSELSYTFSHASEDIRKTFEINQKSGDITLTAPLDFEAIESYS 316
Query: 291 IVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTL 350
I+++AT D + +T+ + T ++ + E +P +V++
Sbjct: 317 IIIQAT--DGGGLFGKSTVRIQVMDVNDNAP-----EITVSSITSPIPEN-TPETVVMVF 368
Query: 351 TTVPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSIS 410
+++ + D F+ K ++NN + R LD E+ + Y + VTD +
Sbjct: 369 RIRDRDSGDNGKMVCSIPEDIPFVLKSSVNNYYTLETERPLDRESRAEYNITITVTDLGT 428
Query: 411 ---NDTASINISVEDVNEWEPRFRHPQY 435
+I + V DVN+ P F Y
Sbjct: 429 PRLKTEHNITVLVSDVNDNAPAFTQTSY 456
Score = 91.9 bits (218), Expect = 9e-18
Identities = 116/478 (24%), Positives = 182/478 (38%), Gaps = 30/478 (6%)
Query: 57 LTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVR 116
L L +ALD EE+ P ++ D + V V V D+NDN+P++E A Y V+
Sbjct: 194 LVLDKALDYEER--PELSFILTALDGGSPPRSGTAL-VRVVVVDINDNSPEFEQAFYEVK 250
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFE-NELEPIIVVKKPLDF 175
+ E D D G +S L Y FE N+ I + PLDF
Sbjct: 251 ILENSILGSLVVTVSAWDLDS-GTNSELSYTFSHASEDIRKTFEINQKSGDITLTAPLDF 309
Query: 176 ETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLT 235
E + +++I ++ D G L+ +T+++ V+D +D P+ T T+ +P++ E +
Sbjct: 310 EAIESYSIIIQATDGGG--LFGKSTVRIQVMDVNDNAPEITVSSITSPIPENTPETVVMV 367
Query: 236 TSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQ-LIAELDPSVTIVLK 294
D+D G N + S D ++ + + T++ L E I +
Sbjct: 368 -----FRIRDRDSGDNGKMVCSIPEDIPFVLKSSVNNYYTLETERPLDRESRAEYNITIT 422
Query: 295 ATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASP----GSVLLTL 350
T + P L T FTQ Y+ V E SP GS+ T
Sbjct: 423 VTDLGTP---RLKTEHNITVLVSDVNDNAPA--FTQTSYALFVRENNSPALHIGSISATD 477
Query: 351 TTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTDSI 409
N + S L +IN + G + RSLDYE + ++V TD
Sbjct: 478 RDSGTNAQVNYSLLPSQDPHLPLASLVSINADNGHLFALRSLDYEALQGFQFRVGATDHG 537
Query: 410 S---NDTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGDAG 466
S + A + + V D N+ P +P VA DGD+G
Sbjct: 538 SPALSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPWAAEPGYLVTKVVAVDGDSG 597
Query: 467 TLA-LS---LAGQHARMFYINASGDLFLREEAIGNLNSSSLHLVATAIDSGIPPRQTS 520
A LS L +F + A + +++ LV D+G PPR +
Sbjct: 598 QNAWLSYQLLKATEPGLFGVWAHNGEVRTARLLSERDAAKHRLVVLVKDNGEPPRSAT 655
Score = 79.8 bits (188), Expect = 4e-14
Identities = 91/315 (28%), Positives = 134/315 (42%), Gaps = 28/315 (8%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAV--GIVPGSKNLTLLRALDREEK 68
I E+TP +++ + S D G + + E V V L R LDRE +
Sbjct: 356 IPENTP-ETVVMVFRIRDRDSGDNGKMVCSIPEDIPFVLKSSVNNYYTLETERPLDRESR 414
Query: 69 IGPSNVYVNVRC--DRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXX 126
N+ + V R T+ + + VS DVNDNAP + YA+ V E
Sbjct: 415 -AEYNITITVTDLGTPRLKTEHNITVLVS----DVNDNAPAFTQTSYALFVRENNSPALH 469
Query: 127 XXXXXXSDRDQPGPHSALHYAVLPG--PHSEYLGFE--NELEPIIVVKKPLDFETVNNFT 182
+DRD G ++ ++Y++LP PH N + + LD+E + F
Sbjct: 470 IGSISATDRDS-GTNAQVNYSLLPSQDPHLPLASLVSINADNGHLFALRSLDYEALQGFQ 528
Query: 183 IKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTY------EHYTALLPDDAEEGTFLTT 236
++ D GSP L S+ ++V VLDA+D +P Y T L+P AE G +T
Sbjct: 529 FRVGATDHGSPALSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPWAAEPGYLVT- 587
Query: 237 SPGPISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPSV-TIVLK 294
+ A D D G NA L Y L V G+V T +L++E D + +V+
Sbjct: 588 ---KVVAVDGDSGQNAWLSYQLLKATEPGLFGVWAHNGEV-RTARLLSERDAAKHRLVVL 643
Query: 295 ATQVDNPDRYALATL 309
P R A ATL
Sbjct: 644 VKDNGEPPRSATATL 658
>AF152491-1|AAD43752.1| 795|Homo sapiens protocadherin beta 12
protein.
Length = 795
Score = 97.9 bits (233), Expect = 1e-19
Identities = 101/448 (22%), Positives = 188/448 (41%), Gaps = 33/448 (7%)
Query: 3 GGAVESFFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRL--QEKGAAVGIVPGSKNLTL 59
G +F + E+ GS +G L+ G +L R+ + + + + +L L
Sbjct: 27 GSETGNFLVMEELQSGSFVGNLAKTLGLEVSELSSRGARVVSNDNKECLQLDTNTGDLLL 86
Query: 60 LRALDREEKIG---PSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVR 116
LDREE G P +Y V +P+ + + ++V D+ND++P + +
Sbjct: 87 REMLDREELCGSNEPCVLYFQVLMK-----NPTQFLQIELQVRDINDHSPVFLEKEMLLE 141
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEY---LGFENELEPIIVVKKPL 173
+ E D D G ++ Y + P H + +N P +V+ K L
Sbjct: 142 IPENSPVGAVFLLESAKDLDV-GINAVKSYTINPNSHFHVKIRVNPDNRKYPELVLDKAL 200
Query: 174 DFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTF 233
D+E + L D GSPP ++V V+D +D +P+F Y + +++ G+
Sbjct: 201 DYEERPELSFILTALDGGSPPRSGTALVRVVVVDINDNSPEFEQAFYEVKILENSILGSL 260
Query: 234 LTTSPGPISAADQDLGINAPLQYS---STGDHKQLIVVNKDTGQVAATKQLIAELDPSVT 290
+ T +SA D D G N+ L Y+ ++ D ++ +N+ +G + T L E S +
Sbjct: 261 VVT----VSAWDLDSGTNSELSYTFSHASEDIRKTFEINQKSGDITLTAPLDFEAIESYS 316
Query: 291 IVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTL 350
I+++AT D + +T+ + T ++ + E +P +V++
Sbjct: 317 IIIQAT--DGGGLFGKSTVRIQVMDVNDNAP-----EITVSSITSPIPEN-TPETVVMVF 368
Query: 351 TTVPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSIS 410
+++ + D F+ K ++NN + R LD E+ + Y + VTD +
Sbjct: 369 RIRDRDSGDNGKMVCSIPEDIPFVLKSSVNNYYTLETERPLDRESRAEYNITITVTDLGT 428
Query: 411 ---NDTASINISVEDVNEWEPRFRHPQY 435
+I + V DVN+ P F Y
Sbjct: 429 PRLKTEHNITVLVSDVNDNAPAFTQTSY 456
Score = 91.9 bits (218), Expect = 9e-18
Identities = 116/478 (24%), Positives = 182/478 (38%), Gaps = 30/478 (6%)
Query: 57 LTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVR 116
L L +ALD EE+ P ++ D + V V V D+NDN+P++E A Y V+
Sbjct: 194 LVLDKALDYEER--PELSFILTALDGGSPPRSGTAL-VRVVVVDINDNSPEFEQAFYEVK 250
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFE-NELEPIIVVKKPLDF 175
+ E D D G +S L Y FE N+ I + PLDF
Sbjct: 251 ILENSILGSLVVTVSAWDLDS-GTNSELSYTFSHASEDIRKTFEINQKSGDITLTAPLDF 309
Query: 176 ETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLT 235
E + +++I ++ D G L+ +T+++ V+D +D P+ T T+ +P++ E +
Sbjct: 310 EAIESYSIIIQATDGGG--LFGKSTVRIQVMDVNDNAPEITVSSITSPIPENTPETVVMV 367
Query: 236 TSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQ-LIAELDPSVTIVLK 294
D+D G N + S D ++ + + T++ L E I +
Sbjct: 368 -----FRIRDRDSGDNGKMVCSIPEDIPFVLKSSVNNYYTLETERPLDRESRAEYNITIT 422
Query: 295 ATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASP----GSVLLTL 350
T + P L T FTQ Y+ V E SP GS+ T
Sbjct: 423 VTDLGTP---RLKTEHNITVLVSDVNDNAPA--FTQTSYALFVRENNSPALHIGSISATD 477
Query: 351 TTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTDSI 409
N + S L +IN + G + RSLDYE + ++V TD
Sbjct: 478 RDSGTNAQVNYSLLPSQDPHLPLASLVSINADNGHLFALRSLDYEALQGFQFRVGATDHG 537
Query: 410 S---NDTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGDAG 466
S + A + + V D N+ P +P VA DGD+G
Sbjct: 538 SPALSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPWAAEPGYLVTKVVAVDGDSG 597
Query: 467 TLA-LS---LAGQHARMFYINASGDLFLREEAIGNLNSSSLHLVATAIDSGIPPRQTS 520
A LS L +F + A + +++ LV D+G PPR +
Sbjct: 598 QNAWLSYQLLKATEPGLFGVWAHNGEVRTARLLSERDAAKHRLVVLVKDNGEPPRSAT 655
Score = 79.8 bits (188), Expect = 4e-14
Identities = 91/315 (28%), Positives = 134/315 (42%), Gaps = 28/315 (8%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAV--GIVPGSKNLTLLRALDREEK 68
I E+TP +++ + S D G + + E V V L R LDRE +
Sbjct: 356 IPENTP-ETVVMVFRIRDRDSGDNGKMVCSIPEDIPFVLKSSVNNYYTLETERPLDRESR 414
Query: 69 IGPSNVYVNVRC--DRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXX 126
N+ + V R T+ + + VS DVNDNAP + YA+ V E
Sbjct: 415 -AEYNITITVTDLGTPRLKTEHNITVLVS----DVNDNAPAFTQTSYALFVRENNSPALH 469
Query: 127 XXXXXXSDRDQPGPHSALHYAVLPG--PHSEYLGFE--NELEPIIVVKKPLDFETVNNFT 182
+DRD G ++ ++Y++LP PH N + + LD+E + F
Sbjct: 470 IGSISATDRDS-GTNAQVNYSLLPSQDPHLPLASLVSINADNGHLFALRSLDYEALQGFQ 528
Query: 183 IKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTY------EHYTALLPDDAEEGTFLTT 236
++ D GSP L S+ ++V VLDA+D +P Y T L+P AE G +T
Sbjct: 529 FRVGATDHGSPALSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPWAAEPGYLVT- 587
Query: 237 SPGPISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPSV-TIVLK 294
+ A D D G NA L Y L V G+V T +L++E D + +V+
Sbjct: 588 ---KVVAVDGDSGQNAWLSYQLLKATEPGLFGVWAHNGEV-RTARLLSERDAAKHRLVVL 643
Query: 295 ATQVDNPDRYALATL 309
P R A ATL
Sbjct: 644 VKDNGEPPRSATATL 658
>AB208959-1|BAD92196.1| 716|Homo sapiens protocadherin beta 9
precursor variant protein.
Length = 716
Score = 97.9 bits (233), Expect = 1e-19
Identities = 97/392 (24%), Positives = 165/392 (42%), Gaps = 30/392 (7%)
Query: 56 NLTLLRALDREEKIGPSN---VYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAP 112
NL LDRE+ GP +Y + D DP + +RV D+ND++P +
Sbjct: 2 NLLTNEKLDREKLCGPKEPCMLYFQILMD-----DPFQIYRAELRVRDINDHSPVFRHKE 56
Query: 113 YAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGP--HSEYLGF-ENELEPIIVV 169
+++SE D D+ G +S +Y + H + G E + P +V+
Sbjct: 57 MVLKISENTAEGTAFRLERAQDPDE-GHNSIQNYTISSNSFFHIKISGSDEGMIYPELVL 115
Query: 170 KKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAE 229
K LD E ++ L D GSP +T+++ VLD +D P+F Y P+++
Sbjct: 116 DKALDGEEQEELSLTLTALDGGSPSRSGTSTIRIVVLDVNDNVPQFAQALYETQAPENSP 175
Query: 230 EGTFLTTSPGPISAADQDLGINAPLQYS---STGDHKQLIVVNKDTGQVAATKQLIAELD 286
G+ + +SA D D G+NA + YS ++ D +N +G++ + L EL
Sbjct: 176 VGSLIV----KVSAGDADSGVNAEVSYSFFDASEDILTTFQINPFSGEIFLRELLDYELV 231
Query: 287 PSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSV 346
S I ++A +D A T+ + S +V+E SPG V
Sbjct: 232 NSYKINIQA--MDGGGLSARCTVLIKVLDSNDNPP-----ELIISSLSNSVAEN-SPGIV 283
Query: 347 LLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVT 406
L +++ + + + F K +++N ++ +LD E+ + Y + VT
Sbjct: 284 LAVFKIKDRDSGENGKTICYVQDNLPFFLKPSVDNFYILMTEGALDRESKAEYNITITVT 343
Query: 407 DSIS---NDTASINISVEDVNEWEPRFRHPQY 435
D + SI + V DVN+ P F Y
Sbjct: 344 DLGTPRLKTEHSITLQVSDVNDNAPAFTQTSY 375
Score = 81.0 bits (191), Expect = 2e-14
Identities = 90/316 (28%), Positives = 136/316 (43%), Gaps = 30/316 (9%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLR---ALDREE 67
++E++P G ++ + S + G +Q+ + P N +L ALDRE
Sbjct: 275 VAENSP-GIVLAVFKIKDRDSGENGKTICYVQDN-LPFFLKPSVDNFYILMTEGALDRES 332
Query: 68 KIGPSNVYVNVRC--DRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXX 125
K N+ + V R T+ S + VS DVNDNAP + Y + V E
Sbjct: 333 K-AEYNITITVTDLGTPRLKTEHSITLQVS----DVNDNAPAFTQTSYTLFVRENNSPAL 387
Query: 126 XXXXXXXSDRDQPGPHSALHYAVLP--GPHSEYLGFE--NELEPIIVVKKPLDFETVNNF 181
+DRD G ++ + Y++LP PH N + + LD+E + F
Sbjct: 388 HIGSVSATDRDS-GTNAQVTYSLLPPQDPHLPLASLVSINADNGHLFALRSLDYEALQAF 446
Query: 182 TIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTY------EHYTALLPDDAEEGTFLT 235
++ D+GSP L S+ ++V VLDA+D +P Y T L+P AE G +T
Sbjct: 447 DFRVGASDRGSPALSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVT 506
Query: 236 TSPGPISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPSV-TIVL 293
+ A D D G NA L Y L V G+V T +L++E D + +V+
Sbjct: 507 ----KVVAVDGDSGQNAWLSYQLLKATEPGLFGVWAHNGEV-RTARLLSERDAAKHRLVV 561
Query: 294 KATQVDNPDRYALATL 309
P R A ATL
Sbjct: 562 LVKDNGEPPRSATATL 577
Score = 66.1 bits (154), Expect = 5e-10
Identities = 100/441 (22%), Positives = 159/441 (36%), Gaps = 27/441 (6%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
+ + V DVNDN PQ+ A Y + E D D G ++ + Y+
Sbjct: 147 IRIVVLDVNDNVPQFAQALYETQAPENSPVGSLIVKVSAGDADS-GVNAEVSYSFFDASE 205
Query: 154 SEYLGFE-NELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQN 212
F+ N I +++ LD+E VN++ I ++ D G L + T+ + VLD++D
Sbjct: 206 DILTTFQINPFSGEIFLRELLDYELVNSYKINIQAMDGGG--LSARCTVLIKVLDSNDNP 263
Query: 213 PKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDT 272
P+ + + +++ G L D+D G N + + + D
Sbjct: 264 PELIISSLSNSVAENSP-GIVLAV----FKIKDRDSGENGKTICYVQDNLPFFLKPSVDN 318
Query: 273 GQVAATK-QLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQK 331
+ T+ L E I + T + P L T FTQ
Sbjct: 319 FYILMTEGALDRESKAEYNITITVTDLGTP---RLKTEHSITLQVSDVNDNAPA--FTQT 373
Query: 332 QYSTTVSEGASP----GSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVI 386
Y+ V E SP GSV T N + S L +IN + G +
Sbjct: 374 SYTLFVRENNSPALHIGSVSATDRDSGTNAQVTYSLLPPQDPHLPLASLVSINADNGHLF 433
Query: 387 LRRSLDYETTSNYFYQVMVTDSIS---NDTASINISVEDVNEWEPRFRHPQYEFEXXXXX 443
RSLDYE + ++V +D S + A + + V D N+ P +P
Sbjct: 434 ALRSLDYEALQAFDFRVGASDRGSPALSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTE 493
Query: 444 XXXXXXXXXXXXXXXVAHDGDAGTLA-LS---LAGQHARMFYINASGDLFLREEAIGNLN 499
VA DGD+G A LS L +F + A + +
Sbjct: 494 LVPRAAEPGYLVTKVVAVDGDSGQNAWLSYQLLKATEPGLFGVWAHNGEVRTARLLSERD 553
Query: 500 SSSLHLVATAIDSGIPPRQTS 520
++ LV D+G PPR +
Sbjct: 554 AAKHRLVVLVKDNGEPPRSAT 574
Score = 33.5 bits (73), Expect = 3.4
Identities = 40/174 (22%), Positives = 65/174 (37%), Gaps = 10/174 (5%)
Query: 328 FTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLD-KFAINNAG--- 383
F K+ +SE + G+ L E S + +S SF K + ++ G
Sbjct: 52 FRHKEMVLKISENTAEGTAF-RLERAQDPDEGHNSIQNYTISSNSFFHIKISGSDEGMIY 110
Query: 384 -EVILRRSLDYETTSNYFYQVMVTDSIS---NDTASINISVEDVNEWEPRFRHPQYEFEX 439
E++L ++LD E + D S + T++I I V DVN+ P+F YE +
Sbjct: 111 PELVLDKALDGEEQEELSLTLTALDGGSPSRSGTSTIRIVVLDVNDNVPQFAQALYETQA 170
Query: 440 XXXXXXXXXXXXXXXXXXXVAHDGDAGTLALSLAGQHARMFYINA-SGDLFLRE 492
+ + + F IN SG++FLRE
Sbjct: 171 PENSPVGSLIVKVSAGDADSGVNAEVSYSFFDASEDILTTFQINPFSGEIFLRE 224
>BC101805-1|AAI01806.1| 811|Homo sapiens protocadherin gamma
subfamily B, 2 protein.
Length = 811
Score = 97.5 bits (232), Expect = 2e-19
Identities = 101/437 (23%), Positives = 185/437 (42%), Gaps = 24/437 (5%)
Query: 9 FFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREE 67
+ I E+ S++G L+ + G DL LR+ + + P S +L + +DRE+
Sbjct: 35 YSIPEELAKNSVVGNLAKDLGLSVRDLPARKLRVSAEKEYFTVNPESGDLLVSDRIDREQ 94
Query: 68 KIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXX 127
G + V + D +P + ++V V D+NDN P ++ +++ E+
Sbjct: 95 ICGKQPLCV-LDFDTV-AENPLNIFYIAVIVQDINDNTPLFKQTKINLKIGESTKPGTTF 152
Query: 128 XXXXXSDRDQPGPHSALHYAVLPGPH---SEYLGFENELEPIIVVKKPLDFETVNNFTIK 184
D D GP+S Y + + +E + P +++K LD E + +
Sbjct: 153 PLDPALDSDV-GPNSLQRYHLNDNEYFDLAEKQTPDGRKYPELILKHSLDREEHSLHQLV 211
Query: 185 LRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAA 244
L D G PP T +++ V DA+D P F+ + Y L +D G F+ ++A
Sbjct: 212 LTAVDGGDPPQSGTTQIRIKVTDANDNPPVFSQDVYRVTLREDVPPGFFVL----QVTAT 267
Query: 245 DQDLGINAPLQYSSTGDHKQL---IVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNP 301
D+D GINA + YS +Q+ +N+ TG++ L E+ S T+ ++A D
Sbjct: 268 DRDEGINAEITYSFHNVDEQVKHFFNLNEKTGEITTKDDLDFEIASSYTLSIEAK--DPG 325
Query: 302 DRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRE 361
D A ++ + ST + E + PG+V+ + T +++
Sbjct: 326 DLAAHCSIQVEILDDNDCAP-----EVIVTSVSTPLPEDSPPGTVIALIKTRDRDSGENG 380
Query: 362 SPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSISNDTAS---INI 418
+ + F+ K + N +++ +LD E Y + TD +S + +
Sbjct: 381 EVYCQVLGNAKFILKSSSKNYYKLVTDGALDREEIPEYNLTITATDGGKPPLSSSIIVTL 440
Query: 419 SVEDVNEWEPRFRHPQY 435
+ DVN+ P F+ Y
Sbjct: 441 HISDVNDNAPVFQQTSY 457
Score = 78.6 bits (185), Expect = 9e-14
Identities = 77/286 (26%), Positives = 126/286 (44%), Gaps = 24/286 (8%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLL---RALDREE 67
+ ED+P G++I + S + G++ ++ + + SKN L ALDREE
Sbjct: 356 LPEDSPPGTVIALIKTRDRDSGENGEVYCQVLGNAKFI-LKSSSKNYYKLVTDGALDREE 414
Query: 68 KIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXX 127
I N+ + + S + V++ + DVNDNAP ++ Y V V+E
Sbjct: 415 -IPEYNLTITATDGGKPPLSSSII--VTLHISDVNDNAPVFQQTSYMVHVAENNPPGASI 471
Query: 128 XXXXXSDRDQPGPHSALHYAVLPGPHS--EYLGFEN--ELEPIIVVKKPLDFETVNNFTI 183
SD D GP + Y+++ E L + + ++ ++ D E + F +
Sbjct: 472 AQISASDPDL-GPSGQVSYSIVASDLKPREILSYVSVSAQSGVVFAQRAFDHEQLRAFEL 530
Query: 184 KLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHY----TAL---LPDDAEEGTFLTT 236
L+ +DQGSP L ++ +L+V V D +D P+ Y +AL +P AE G +T
Sbjct: 531 TLQARDQGSPALSANVSLRVLVGDLNDNAPRVLYPALGPDGSALFDMVPRAAEPGYLVT- 589
Query: 237 SPGPISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQL 281
+ A D D G NA L Y L + TG+V + L
Sbjct: 590 ---KVVAVDADSGHNAWLSYHVLQASEPGLFSLGLRTGEVRTARAL 632
Score = 71.3 bits (167), Expect = 1e-11
Identities = 95/438 (21%), Positives = 167/438 (38%), Gaps = 27/438 (6%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
+ ++V D NDN P + Y V + E +DRD+ G ++ + Y+
Sbjct: 228 IRIKVTDANDNPPVFSQDVYRVTLREDVPPGFFVLQVTATDRDE-GINAEITYSFHNVDE 286
Query: 154 SEYLGFE-NELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQN 212
F NE I K LDFE +++T+ + +D G L + ++QV +LD +D
Sbjct: 287 QVKHFFNLNEKTGEITTKDDLDFEIASSYTLSIEAKDPGD--LAAHCSIQVEILDDNDCA 344
Query: 213 PKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLI-VVNKD 271
P+ + LP+D+ GT + I D+D G N + G+ K ++ +K+
Sbjct: 345 PEVIVTSVSTPLPEDSPPGTVIAL----IKTRDRDSGENGEVYCQVLGNAKFILKSSSKN 400
Query: 272 TGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQK 331
++ L E P + + AT P + + F Q
Sbjct: 401 YYKLVTDGALDREEIPEYNLTITATDGGKPPLSSSIIVTLHISDVNDNAPV-----FQQT 455
Query: 332 QYSTTVSEGASPGSVLLTLT-TVPQNTEFRESPLQFYVSD---RSFLDKFAIN-NAGEVI 386
Y V+E PG+ + ++ + P + SD R L +++ +G V
Sbjct: 456 SYMVHVAENNPPGASIAQISASDPDLGPSGQVSYSIVASDLKPREILSYVSVSAQSGVVF 515
Query: 387 LRRSLDYETTSNYFYQVMVTDSIS---NDTASINISVEDVNEWEPRFRHPQYEFEXXXXX 443
+R+ D+E + + D S + S+ + V D+N+ PR +P +
Sbjct: 516 AQRAFDHEQLRAFELTLQARDQGSPALSANVSLRVLVGDLNDNAPRVLYPALGPDGSALF 575
Query: 444 XXX-XXXXXXXXXXXXVAHDGDAGTLA-LS---LAGQHARMFYINASGDLFLREEAIGNL 498
VA D D+G A LS L +F + A+G+
Sbjct: 576 DMVPRAAEPGYLVTKVVAVDADSGHNAWLSYHVLQASEPGLFSLGLRTGEVRTARALGDR 635
Query: 499 NSSSLHLVATAIDSGIPP 516
+++ L+ D G PP
Sbjct: 636 DAARQRLLVAVRDGGQPP 653
>AF152518-1|AAD43778.1| 811|Homo sapiens protocadherin gamma B2
short form protein protein.
Length = 811
Score = 97.5 bits (232), Expect = 2e-19
Identities = 101/437 (23%), Positives = 185/437 (42%), Gaps = 24/437 (5%)
Query: 9 FFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREE 67
+ I E+ S++G L+ + G DL LR+ + + P S +L + +DRE+
Sbjct: 35 YSIPEELAKNSVVGNLAKDLGLSVRDLPARKLRVSAEKEYFTVNPESGDLLVSDRIDREQ 94
Query: 68 KIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXX 127
G + V + D +P + ++V V D+NDN P ++ +++ E+
Sbjct: 95 ICGKQPLCV-LDFDTV-AENPLNIFYIAVIVQDINDNTPLFKQTKINLKIGESTKPGTTF 152
Query: 128 XXXXXSDRDQPGPHSALHYAVLPGPH---SEYLGFENELEPIIVVKKPLDFETVNNFTIK 184
D D GP+S Y + + +E + P +++K LD E + +
Sbjct: 153 PLDPALDSDV-GPNSLQRYHLNDNEYFDLAEKQTPDGRKYPELILKHSLDREEHSLHQLV 211
Query: 185 LRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAA 244
L D G PP T +++ V DA+D P F+ + Y L +D G F+ ++A
Sbjct: 212 LTAVDGGDPPQSGTTQIRIKVTDANDNPPVFSQDVYRVTLREDVPPGFFVL----QVTAT 267
Query: 245 DQDLGINAPLQYSSTGDHKQL---IVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNP 301
D+D GINA + YS +Q+ +N+ TG++ L E+ S T+ ++A D
Sbjct: 268 DRDEGINAEITYSFHNVDEQVKHFFNLNEKTGEITTKDDLDFEIASSYTLSIEAK--DPG 325
Query: 302 DRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRE 361
D A ++ + ST + E + PG+V+ + T +++
Sbjct: 326 DLAAHCSIQVEILDDNDCAP-----EVIVTSVSTPLPEDSPPGTVIALIKTRDRDSGENG 380
Query: 362 SPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSISNDTAS---INI 418
+ + F+ K + N +++ +LD E Y + TD +S + +
Sbjct: 381 EVYCQVLGNAKFILKSSSKNYYKLVTDGALDREEIPEYNLTITATDGGKPPLSSSIIVTL 440
Query: 419 SVEDVNEWEPRFRHPQY 435
+ DVN+ P F+ Y
Sbjct: 441 HISDVNDNAPVFQQTSY 457
Score = 78.6 bits (185), Expect = 9e-14
Identities = 77/286 (26%), Positives = 126/286 (44%), Gaps = 24/286 (8%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLL---RALDREE 67
+ ED+P G++I + S + G++ ++ + + SKN L ALDREE
Sbjct: 356 LPEDSPPGTVIALIKTRDRDSGENGEVYCQVLGNAKFI-LKSSSKNYYKLVTDGALDREE 414
Query: 68 KIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXX 127
I N+ + + S + V++ + DVNDNAP ++ Y V V+E
Sbjct: 415 -IPEYNLTITATDGGKPPLSSSII--VTLHISDVNDNAPVFQQTSYMVHVAENNPPGASI 471
Query: 128 XXXXXSDRDQPGPHSALHYAVLPGPHS--EYLGFEN--ELEPIIVVKKPLDFETVNNFTI 183
SD D GP + Y+++ E L + + ++ ++ D E + F +
Sbjct: 472 AQISASDPDL-GPSGQVSYSIVASDLKPREILSYVSVSAQSGVVFAQRAFDHEQLRAFEL 530
Query: 184 KLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHY----TAL---LPDDAEEGTFLTT 236
L+ +DQGSP L ++ +L+V V D +D P+ Y +AL +P AE G +T
Sbjct: 531 TLQARDQGSPALSANVSLRVLVGDLNDNAPRVLYPALGPDGSALFDMVPRAAEPGYLVT- 589
Query: 237 SPGPISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQL 281
+ A D D G NA L Y L + TG+V + L
Sbjct: 590 ---KVVAVDADSGHNAWLSYHVLQASEPGLFSLGLRTGEVRTARAL 632
Score = 71.3 bits (167), Expect = 1e-11
Identities = 95/438 (21%), Positives = 167/438 (38%), Gaps = 27/438 (6%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
+ ++V D NDN P + Y V + E +DRD+ G ++ + Y+
Sbjct: 228 IRIKVTDANDNPPVFSQDVYRVTLREDVPPGFFVLQVTATDRDE-GINAEITYSFHNVDE 286
Query: 154 SEYLGFE-NELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQN 212
F NE I K LDFE +++T+ + +D G L + ++QV +LD +D
Sbjct: 287 QVKHFFNLNEKTGEITTKDDLDFEIASSYTLSIEAKDPGD--LAAHCSIQVEILDDNDCA 344
Query: 213 PKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLI-VVNKD 271
P+ + LP+D+ GT + I D+D G N + G+ K ++ +K+
Sbjct: 345 PEVIVTSVSTPLPEDSPPGTVIAL----IKTRDRDSGENGEVYCQVLGNAKFILKSSSKN 400
Query: 272 TGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQK 331
++ L E P + + AT P + + F Q
Sbjct: 401 YYKLVTDGALDREEIPEYNLTITATDGGKPPLSSSIIVTLHISDVNDNAPV-----FQQT 455
Query: 332 QYSTTVSEGASPGSVLLTLT-TVPQNTEFRESPLQFYVSD---RSFLDKFAIN-NAGEVI 386
Y V+E PG+ + ++ + P + SD R L +++ +G V
Sbjct: 456 SYMVHVAENNPPGASIAQISASDPDLGPSGQVSYSIVASDLKPREILSYVSVSAQSGVVF 515
Query: 387 LRRSLDYETTSNYFYQVMVTDSIS---NDTASINISVEDVNEWEPRFRHPQYEFEXXXXX 443
+R+ D+E + + D S + S+ + V D+N+ PR +P +
Sbjct: 516 AQRAFDHEQLRAFELTLQARDQGSPALSANVSLRVLVGDLNDNAPRVLYPALGPDGSALF 575
Query: 444 XXX-XXXXXXXXXXXXVAHDGDAGTLA-LS---LAGQHARMFYINASGDLFLREEAIGNL 498
VA D D+G A LS L +F + A+G+
Sbjct: 576 DMVPRAAEPGYLVTKVVAVDADSGHNAWLSYHVLQASEPGLFSLGLRTGEVRTARALGDR 635
Query: 499 NSSSLHLVATAIDSGIPP 516
+++ L+ D G PP
Sbjct: 636 DAARQRLLVAVRDGGQPP 653
>AF152331-1|AAD43725.1| 931|Homo sapiens protocadherin gamma B2
protein.
Length = 931
Score = 97.5 bits (232), Expect = 2e-19
Identities = 101/437 (23%), Positives = 185/437 (42%), Gaps = 24/437 (5%)
Query: 9 FFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREE 67
+ I E+ S++G L+ + G DL LR+ + + P S +L + +DRE+
Sbjct: 35 YSIPEELAKNSVVGNLAKDLGLSVRDLPARKLRVSAEKEYFTVNPESGDLLVSDRIDREQ 94
Query: 68 KIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXX 127
G + V + D +P + ++V V D+NDN P ++ +++ E+
Sbjct: 95 ICGKQPLCV-LDFDTV-AENPLNIFYIAVIVQDINDNTPLFKQTKINLKIGESTKPGTTF 152
Query: 128 XXXXXSDRDQPGPHSALHYAVLPGPH---SEYLGFENELEPIIVVKKPLDFETVNNFTIK 184
D D GP+S Y + + +E + P +++K LD E + +
Sbjct: 153 PLDPALDSDV-GPNSLQRYHLNDNEYFDLAEKQTPDGRKYPELILKHSLDREEHSLHQLV 211
Query: 185 LRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAA 244
L D G PP T +++ V DA+D P F+ + Y L +D G F+ ++A
Sbjct: 212 LTAVDGGDPPQSGTTQIRIKVTDANDNPPVFSQDVYRVTLREDVPPGFFVL----QVTAT 267
Query: 245 DQDLGINAPLQYSSTGDHKQL---IVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNP 301
D+D GINA + YS +Q+ +N+ TG++ L E+ S T+ ++A D
Sbjct: 268 DRDEGINAEITYSFHNVDEQVKHFFNLNEKTGEITTKDDLDFEIASSYTLSIEAK--DPG 325
Query: 302 DRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRE 361
D A ++ + ST + E + PG+V+ + T +++
Sbjct: 326 DLAAHCSIQVEILDDNDCAP-----EVIVTSVSTPLPEDSPPGTVIALIKTRDRDSGENG 380
Query: 362 SPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSISNDTAS---INI 418
+ + F+ K + N +++ +LD E Y + TD +S + +
Sbjct: 381 EVYCQVLGNAKFILKSSSKNYYKLVTDGALDREEIPEYNLTITATDGGKPPLSSSIIVTL 440
Query: 419 SVEDVNEWEPRFRHPQY 435
+ DVN+ P F+ Y
Sbjct: 441 HISDVNDNAPVFQQTSY 457
Score = 78.6 bits (185), Expect = 9e-14
Identities = 77/286 (26%), Positives = 126/286 (44%), Gaps = 24/286 (8%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLL---RALDREE 67
+ ED+P G++I + S + G++ ++ + + SKN L ALDREE
Sbjct: 356 LPEDSPPGTVIALIKTRDRDSGENGEVYCQVLGNAKFI-LKSSSKNYYKLVTDGALDREE 414
Query: 68 KIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXX 127
I N+ + + S + V++ + DVNDNAP ++ Y V V+E
Sbjct: 415 -IPEYNLTITATDGGKPPLSSSII--VTLHISDVNDNAPVFQQTSYMVHVAENNPPGASI 471
Query: 128 XXXXXSDRDQPGPHSALHYAVLPGPHS--EYLGFEN--ELEPIIVVKKPLDFETVNNFTI 183
SD D GP + Y+++ E L + + ++ ++ D E + F +
Sbjct: 472 AQISASDPDL-GPSGQVSYSIVASDLKPREILSYVSVSAQSGVVFAQRAFDHEQLRAFEL 530
Query: 184 KLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHY----TAL---LPDDAEEGTFLTT 236
L+ +DQGSP L ++ +L+V V D +D P+ Y +AL +P AE G +T
Sbjct: 531 TLQARDQGSPALSANVSLRVLVGDLNDNAPRVLYPALGPDGSALFDMVPRAAEPGYLVT- 589
Query: 237 SPGPISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQL 281
+ A D D G NA L Y L + TG+V + L
Sbjct: 590 ---KVVAVDADSGHNAWLSYHVLQASEPGLFSLGLRTGEVRTARAL 632
Score = 71.3 bits (167), Expect = 1e-11
Identities = 95/438 (21%), Positives = 167/438 (38%), Gaps = 27/438 (6%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
+ ++V D NDN P + Y V + E +DRD+ G ++ + Y+
Sbjct: 228 IRIKVTDANDNPPVFSQDVYRVTLREDVPPGFFVLQVTATDRDE-GINAEITYSFHNVDE 286
Query: 154 SEYLGFE-NELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQN 212
F NE I K LDFE +++T+ + +D G L + ++QV +LD +D
Sbjct: 287 QVKHFFNLNEKTGEITTKDDLDFEIASSYTLSIEAKDPGD--LAAHCSIQVEILDDNDCA 344
Query: 213 PKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLI-VVNKD 271
P+ + LP+D+ GT + I D+D G N + G+ K ++ +K+
Sbjct: 345 PEVIVTSVSTPLPEDSPPGTVIAL----IKTRDRDSGENGEVYCQVLGNAKFILKSSSKN 400
Query: 272 TGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQK 331
++ L E P + + AT P + + F Q
Sbjct: 401 YYKLVTDGALDREEIPEYNLTITATDGGKPPLSSSIIVTLHISDVNDNAPV-----FQQT 455
Query: 332 QYSTTVSEGASPGSVLLTLT-TVPQNTEFRESPLQFYVSD---RSFLDKFAIN-NAGEVI 386
Y V+E PG+ + ++ + P + SD R L +++ +G V
Sbjct: 456 SYMVHVAENNPPGASIAQISASDPDLGPSGQVSYSIVASDLKPREILSYVSVSAQSGVVF 515
Query: 387 LRRSLDYETTSNYFYQVMVTDSIS---NDTASINISVEDVNEWEPRFRHPQYEFEXXXXX 443
+R+ D+E + + D S + S+ + V D+N+ PR +P +
Sbjct: 516 AQRAFDHEQLRAFELTLQARDQGSPALSANVSLRVLVGDLNDNAPRVLYPALGPDGSALF 575
Query: 444 XXX-XXXXXXXXXXXXVAHDGDAGTLA-LS---LAGQHARMFYINASGDLFLREEAIGNL 498
VA D D+G A LS L +F + A+G+
Sbjct: 576 DMVPRAAEPGYLVTKVVAVDADSGHNAWLSYHVLQASEPGLFSLGLRTGEVRTARALGDR 635
Query: 499 NSSSLHLVATAIDSGIPP 516
+++ L+ D G PP
Sbjct: 636 DAARQRLLVAVRDGGQPP 653
>BC036786-1|AAH36786.1| 630|Homo sapiens CDH7 protein protein.
Length = 630
Score = 97.1 bits (231), Expect = 2e-19
Identities = 106/444 (23%), Positives = 193/444 (43%), Gaps = 37/444 (8%)
Query: 9 FFISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAA-VGIVP-GSKNLTLLRALDRE 66
FF+ E+ + ++ D + G I L +GA+ + I+ + ++ + LDRE
Sbjct: 54 FFVLEEYMGSDPLYVGKLHSDVDKGDGSIKYILSGEGASSIFIIDENTGDIHATKRLDRE 113
Query: 67 EKIGPSNVYVNVRCDR--RRTTDPSFVIPVS---VRVWDVNDNAPQWEGAPYAVRVSETX 121
E+ Y +R R T +P V P S +++ D+NDN P++ PY V E
Sbjct: 114 EQ-----AYYTLRAQALDRLTNEP--VEPESEFVIKIQDINDNEPKFLDGPYTAGVPEMS 166
Query: 122 XXXXXXXXXXXSDRDQP--GPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVN 179
+D D P G + + Y++L G Y E + I +D E +
Sbjct: 167 PVGTSVVQVTATDADDPTYGNSARVVYSILQG--QPYFSVEPKTGVIKTALPNMDREAKD 224
Query: 180 NFTIKLRVQDQ--GSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTS 237
+ + ++ +D + L T++ VT+ D +D P+F Y +P+ + +
Sbjct: 225 QYLLVIQAKDMVGQNGGLSGTTSVTVTLTDVNDNPPRFPRRSYQYNVPESLPVASVVAR- 283
Query: 238 PGPISAADQDLGINAPLQYSST-GDHKQL--IVVNKDT--GQVAATKQLIAELDPSVTIV 292
I AAD D+G NA ++Y GD + I V+K+T G + K+L E S T+
Sbjct: 284 ---IKAADADIGANAEMEYKIVDGDGLGIFKISVDKETQEGIITIQKELDFEAKTSYTLR 340
Query: 293 LKATQVDNPDRY-ALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLT 351
++A D R+ +L F+ Y VSE G+++ T+
Sbjct: 341 IEAANKDADPRFLSLGPFSDTTTVKIIVEDVDEPPVFSSPLYPMEVSEATQVGNIIGTVA 400
Query: 352 TVPQNTEFRESPLQFYVSDRSFLDK-FAIN-NAGEVILRRSLDYETTSNYFYQVMVTDSI 409
+ + SP+++ + + L++ F I+ N+G + +SLD ET + + V+ +S
Sbjct: 401 A--HDPDSSNSPVRYSIDRNTDLERYFNIDANSGVITTAKSLDRETNAIHNITVLAMESQ 458
Query: 410 SNDTAS---INISVEDVNEWEPRF 430
+ + I++ D+N+ P F
Sbjct: 459 NPSQVGRGYVAITILDINDNAPEF 482
Score = 82.2 bits (194), Expect = 7e-15
Identities = 84/349 (24%), Positives = 153/349 (43%), Gaps = 32/349 (9%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
V+V + DVNDN P++ Y V E+ +D D G ++ + Y ++ G
Sbjct: 248 VTVTLTDVNDNPPRFPRRSYQYNVPESLPVASVVARIKAADADI-GANAEMEYKIVDGDG 306
Query: 154 SEY--LGFENEL-EPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLY------SDTTLQVT 204
+ + E E II ++K LDFE ++T+++ ++ + P + SDTT
Sbjct: 307 LGIFKISVDKETQEGIITIQKELDFEAKTSYTLRIEAANKDADPRFLSLGPFSDTTTVKI 366
Query: 205 VLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYS--STGDH 262
+++ D+ P F+ + L P + E T + G ++A D D N+P++YS D
Sbjct: 367 IVEDVDEPPVFS----SPLYPMEVSEATQVGNIIGTVAAHDPDSS-NSPVRYSIDRNTDL 421
Query: 263 KQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXX 322
++ ++ ++G + K L E + I + A + NP + +
Sbjct: 422 ERYFNIDANSGVITTAKSLDRETNAIHNITVLAMESQNPSQVGRGYVAITILDINDNAP- 480
Query: 323 XXXLQFTQKQYSTTVSEGASPGSVLLTLTTV----PQN-TEFRESPLQFYVSDRSFLDKF 377
+F Y TTV E A PG V+ ++ V P N +F S ++ +F K
Sbjct: 481 ----EFAM-DYETTVCENAQPGQVIQKISAVDKDEPSNGHQFYFSLTTDATNNHNFSLKD 535
Query: 378 AINNAGEVILRRS-LDYETTSNYFYQVMVTDSIS---NDTASINISVED 422
+N ++ RR+ + S Y+ + + DS S + T+++ I V D
Sbjct: 536 NKDNTASILTRRNGFRRQEQSVYYLPIFIVDSGSPSLSSTSTLTIRVCD 584
Score = 52.0 bits (119), Expect = 9e-06
Identities = 51/233 (21%), Positives = 94/233 (40%), Gaps = 16/233 (6%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAA---VGIVPGSKNLTLLRALDREE 67
+SE T +G+IIGT++ + DP + + I S +T ++LDRE
Sbjct: 386 VSEATQVGNIIGTVAAH-DPDSSNSPVRYSIDRNTDLERYFNIDANSGVITTAKSLDRE- 443
Query: 68 KIGPSNVYVNVRCDRRRTTDPSFVIP--VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXX 125
+N N+ + +PS V V++ + D+NDNAP++ Y V E
Sbjct: 444 ----TNAIHNITVLAMESQNPSQVGRGYVAITILDINDNAPEF-AMDYETTVCENAQPGQ 498
Query: 126 XXXXXXXSDRDQPGPHSALHYAVLPGPHSEY----LGFENELEPIIVVKKPLDFETVNNF 181
D+D+P ++++ + + ++ I+ + + + +
Sbjct: 499 VIQKISAVDKDEPSNGHQFYFSLTTDATNNHNFSLKDNKDNTASILTRRNGFRRQEQSVY 558
Query: 182 TIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFL 234
+ + + D GSP L S +TL + V D D T +LP G +
Sbjct: 559 YLPIFIVDSGSPSLSSTSTLTIRVCDCDADGVAQTCNAEAYVLPAGLSTGALI 611
>AF152473-1|AAD43734.1| 818|Homo sapiens protocadherin alpha C1
short form protein protein.
Length = 818
Score = 97.1 bits (231), Expect = 2e-19
Identities = 113/527 (21%), Positives = 193/527 (36%), Gaps = 21/527 (3%)
Query: 9 FFISEDTPIGSIIGTLSVNGD-PSEDLGDITLRL--QEKGAAVGIVPGSKNLTLLRALDR 65
+ + E+T G +G LS + P+ + R + G+ S NL + DR
Sbjct: 24 YSVPEETERGVAVGNLSADLRLPAAAMSSRNFRFLSSHRELYFGVDLPSGNLVVREPADR 83
Query: 66 EEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXX 125
E+ V + D DP + + + V D NDN+P + + + E
Sbjct: 84 EQLCRAKAACV-LTYDLV-LEDPLELHKIRIHVLDTNDNSPLFPAGDVQLHIPEFLTPGA 141
Query: 126 XXXXXXXSDRDQPGPHSALHYAVLPGPHSEY-LG--FENELEPIIVVKKPLDFETVNNFT 182
D D+ G + L Y++ P H +G + P +V++K LD E
Sbjct: 142 RFTLPNAQDDDE-GSNGILSYSLSPSQHFRLDMGSRVDGSEYPELVLEKALDREQRATHL 200
Query: 183 IKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPIS 242
+ L +D G P D + + V+D +D P F Y +P+ A GT L +
Sbjct: 201 LVLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYRTKVPETAPNGTVLFR----VQ 256
Query: 243 AADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPD 302
A D D G N +QYS + + + + Q+ A L P T++ + +
Sbjct: 257 ALDPDEGSNGEVQYSLSNSTQAELRHRFHVHPKSGEVQVAASLGPPETLLEAYIEARDEG 316
Query: 303 RYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRES 362
+ LA+ L F S V E A+PG+V+ + ++ +
Sbjct: 317 VFGLASTAKLLVEVTDVNDHAPELDFL--TLSNPVPEDAAPGTVIALFSVKDEDLDSNGR 374
Query: 363 PLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSIS---NDTASINIS 419
+ S F + +N +++ LD E S Y + +DS S + +I +S
Sbjct: 375 VICGMSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLITASDSGSPPLSTRRTITVS 434
Query: 420 VEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGDAGTLALSLAGQ---H 476
V DVN+ P F PQ E + +G L + +
Sbjct: 435 VADVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNGLVSYELLDVISEGPSA 494
Query: 477 ARMFYINASGDLFLREEAIGNLNSSSLHLVATAIDSGIPPRQTSVPV 523
+ + + +S + + H D GIPPR +V +
Sbjct: 495 SSLVAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRSATVTI 541
Score = 56.4 bits (130), Expect = 4e-07
Identities = 68/289 (23%), Positives = 109/289 (37%), Gaps = 22/289 (7%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLL--RALDREEK 68
+ ED G++I SV + + G + + G +LL LDRE+
Sbjct: 349 VPEDAAPGTVIALFSVKDEDLDSNGRVICGMSSAGPFQLTASFDNYYSLLIDGPLDREQI 408
Query: 69 IGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXX 128
S V + + S ++V V DVNDN P + + V+E
Sbjct: 409 ---SEYQVLITASDSGSPPLSTRRTITVSVADVNDNTPNFPQPQQELFVAENNGPGASLG 465
Query: 129 XXXXSDRDQPGPHSALHYAVLP----GPHSEYLGFENELEPIIVVKKPLDFETVNNFTIK 184
D D G + + Y +L GP + L I K DFE + F +
Sbjct: 466 RVFAQDPDL-GKNGLVSYELLDVISEGPSASSLVAVESSSGAITAKTSFDFEQLRGFHFQ 524
Query: 185 LRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTY------EHYTALLPDDAEEGTFLTTSP 238
+ +D G PP + T+ + V+D +D P + ++P A G +T
Sbjct: 525 VEGRDGGIPPRSATVTINLFVVDRNDNYPVILFPLPRNGSVPVEIVPRSARTGHLVT--- 581
Query: 239 GPISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELD 286
+ A D D G NA L Y S L ++ + G++ T +L+ D
Sbjct: 582 -KVVAEDADSGSNAWLSYHISRASDSSLFRISANIGEL-RTARLVLPTD 628
Score = 37.1 bits (82), Expect = 0.28
Identities = 79/339 (23%), Positives = 127/339 (37%), Gaps = 31/339 (9%)
Query: 201 LQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYS-ST 259
+++ VLD +D +P F +P+ G T +A D D G N L YS S
Sbjct: 110 IRIHVLDTNDNSPLFPAGDVQLHIPEFLTPGARFTLP----NAQDDDEGSNGILSYSLSP 165
Query: 260 GDHKQLIVVNKDTG----QVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXX 315
H +L + ++ G ++ K L E + +VL A P R A +
Sbjct: 166 SQHFRLDMGSRVDGSEYPELVLEKALDREQRATHLLVLTARDGGLPARSGDAQVTIIVVD 225
Query: 316 XXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLD 375
F + Y T V E A G+VL + + + E +Q+ +S+ + +
Sbjct: 226 TNDNAPV-----FERSVYRTKVPETAPNGTVLFRVQALDPD-EGSNGEVQYSLSNSTQAE 279
Query: 376 ---KFAIN-NAGEVILRRSLDYETTSNYFYQVMVTDSISN--DTASINISVEDVNEWEPR 429
+F ++ +GEV + SL T Y + + TA + + V DVN+
Sbjct: 280 LRHRFHVHPKSGEVQVAASLGPPETLLEAYIEARDEGVFGLASTAKLLVEVTDVND---- 335
Query: 430 FRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGDAGTLALSLAGQH-ARMFYINASGDL 488
P+ +F V D D + + G A F + AS D
Sbjct: 336 -HAPELDFLTLSNPVPEDAAPGTVIALFSVK-DEDLDSNGRVICGMSSAGPFQLTASFDN 393
Query: 489 FLREEAIGNLNS---SSLHLVATAIDSGIPPRQTSVPVT 524
+ G L+ S ++ TA DSG PP T +T
Sbjct: 394 YYSLLIDGPLDREQISEYQVLITASDSGSPPLSTRRTIT 432
>AF152303-1|AAD43697.1| 963|Homo sapiens protocadherin alpha C1
protein.
Length = 963
Score = 97.1 bits (231), Expect = 2e-19
Identities = 113/527 (21%), Positives = 193/527 (36%), Gaps = 21/527 (3%)
Query: 9 FFISEDTPIGSIIGTLSVNGD-PSEDLGDITLRL--QEKGAAVGIVPGSKNLTLLRALDR 65
+ + E+T G +G LS + P+ + R + G+ S NL + DR
Sbjct: 24 YSVPEETERGVAVGNLSADLRLPAAAMSSRNFRFLSSHRELYFGVDLPSGNLVVREPADR 83
Query: 66 EEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXX 125
E+ V + D DP + + + V D NDN+P + + + E
Sbjct: 84 EQLCRAKAACV-LTYDLV-LEDPLELHKIRIHVLDTNDNSPLFPAGDVQLHIPEFLTPGA 141
Query: 126 XXXXXXXSDRDQPGPHSALHYAVLPGPHSEY-LG--FENELEPIIVVKKPLDFETVNNFT 182
D D+ G + L Y++ P H +G + P +V++K LD E
Sbjct: 142 RFTLPNAQDDDE-GSNGILSYSLSPSQHFRLDMGSRVDGSEYPELVLEKALDREQRATHL 200
Query: 183 IKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPIS 242
+ L +D G P D + + V+D +D P F Y +P+ A GT L +
Sbjct: 201 LVLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYRTKVPETAPNGTVLFR----VQ 256
Query: 243 AADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPD 302
A D D G N +QYS + + + + Q+ A L P T++ + +
Sbjct: 257 ALDPDEGSNGEVQYSLSNSTQAELRHRFHVHPKSGEVQVAASLGPPETLLEAYIEARDEG 316
Query: 303 RYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRES 362
+ LA+ L F S V E A+PG+V+ + ++ +
Sbjct: 317 VFGLASTAKLLVEVTDVNDHAPELDFL--TLSNPVPEDAAPGTVIALFSVKDEDLDSNGR 374
Query: 363 PLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSIS---NDTASINIS 419
+ S F + +N +++ LD E S Y + +DS S + +I +S
Sbjct: 375 VICGMSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLITASDSGSPPLSTRRTITVS 434
Query: 420 VEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGDAGTLALSLAGQ---H 476
V DVN+ P F PQ E + +G L + +
Sbjct: 435 VADVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNGLVSYELLDVISEGPSA 494
Query: 477 ARMFYINASGDLFLREEAIGNLNSSSLHLVATAIDSGIPPRQTSVPV 523
+ + + +S + + H D GIPPR +V +
Sbjct: 495 SSLVAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRSATVTI 541
Score = 56.4 bits (130), Expect = 4e-07
Identities = 68/289 (23%), Positives = 109/289 (37%), Gaps = 22/289 (7%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLL--RALDREEK 68
+ ED G++I SV + + G + + G +LL LDRE+
Sbjct: 349 VPEDAAPGTVIALFSVKDEDLDSNGRVICGMSSAGPFQLTASFDNYYSLLIDGPLDREQI 408
Query: 69 IGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXX 128
S V + + S ++V V DVNDN P + + V+E
Sbjct: 409 ---SEYQVLITASDSGSPPLSTRRTITVSVADVNDNTPNFPQPQQELFVAENNGPGASLG 465
Query: 129 XXXXSDRDQPGPHSALHYAVLP----GPHSEYLGFENELEPIIVVKKPLDFETVNNFTIK 184
D D G + + Y +L GP + L I K DFE + F +
Sbjct: 466 RVFAQDPDL-GKNGLVSYELLDVISEGPSASSLVAVESSSGAITAKTSFDFEQLRGFHFQ 524
Query: 185 LRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTY------EHYTALLPDDAEEGTFLTTSP 238
+ +D G PP + T+ + V+D +D P + ++P A G +T
Sbjct: 525 VEGRDGGIPPRSATVTINLFVVDRNDNYPVILFPLPRNGSVPVEIVPRSARTGHLVT--- 581
Query: 239 GPISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELD 286
+ A D D G NA L Y S L ++ + G++ T +L+ D
Sbjct: 582 -KVVAEDADSGSNAWLSYHISRASDSSLFRISANIGEL-RTARLVLPTD 628
Score = 37.1 bits (82), Expect = 0.28
Identities = 79/339 (23%), Positives = 127/339 (37%), Gaps = 31/339 (9%)
Query: 201 LQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYS-ST 259
+++ VLD +D +P F +P+ G T +A D D G N L YS S
Sbjct: 110 IRIHVLDTNDNSPLFPAGDVQLHIPEFLTPGARFTLP----NAQDDDEGSNGILSYSLSP 165
Query: 260 GDHKQLIVVNKDTG----QVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXX 315
H +L + ++ G ++ K L E + +VL A P R A +
Sbjct: 166 SQHFRLDMGSRVDGSEYPELVLEKALDREQRATHLLVLTARDGGLPARSGDAQVTIIVVD 225
Query: 316 XXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLD 375
F + Y T V E A G+VL + + + E +Q+ +S+ + +
Sbjct: 226 TNDNAPV-----FERSVYRTKVPETAPNGTVLFRVQALDPD-EGSNGEVQYSLSNSTQAE 279
Query: 376 ---KFAIN-NAGEVILRRSLDYETTSNYFYQVMVTDSISN--DTASINISVEDVNEWEPR 429
+F ++ +GEV + SL T Y + + TA + + V DVN+
Sbjct: 280 LRHRFHVHPKSGEVQVAASLGPPETLLEAYIEARDEGVFGLASTAKLLVEVTDVND---- 335
Query: 430 FRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGDAGTLALSLAGQH-ARMFYINASGDL 488
P+ +F V D D + + G A F + AS D
Sbjct: 336 -HAPELDFLTLSNPVPEDAAPGTVIALFSVK-DEDLDSNGRVICGMSSAGPFQLTASFDN 393
Query: 489 FLREEAIGNLNS---SSLHLVATAIDSGIPPRQTSVPVT 524
+ G L+ S ++ TA DSG PP T +T
Sbjct: 394 YYSLLIDGPLDREQISEYQVLITASDSGSPPLSTRRTIT 432
>AF231022-1|AAF61928.1| 4349|Homo sapiens protocadherin Fat 2 protein.
Length = 4349
Score = 96.7 bits (230), Expect = 3e-19
Identities = 123/513 (23%), Positives = 203/513 (39%), Gaps = 29/513 (5%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGA-AVGIVPGSKNLTLLRALDREEKI 69
+ ED G I +S ++ IT L GA + P + LT L ALDRE K
Sbjct: 3020 VHEDVFPGHFILKVSATDLDTDTNAQITYSLHGPGAHEFKLDPHTGELTTLTALDRERK- 3078
Query: 70 GPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXX 129
+V+ N+ S +++ V DVNDNAP++ + AV V +
Sbjct: 3079 ---DVF-NLVAKATDGGGRSCQADITLHVEDVNDNAPRFFPSHCAVAVFDNTTVKTPVAV 3134
Query: 130 XXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQD 189
D DQ G ++ + Y+ LP + + +I ++KPL + +R D
Sbjct: 3135 VFARDPDQ-GANAQVVYS-LPDSAEGHFSID-ATTGVIRLEKPLQVRPQAPLELTVRASD 3191
Query: 190 QGSP-PLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDL 248
G+P PL + T+ V+V+ +D P F ++ +P+DA GT + +
Sbjct: 3192 LGTPIPLSTLGTVTVSVVGLEDYLPVFLNTEHSVQVPEDAPPGTEVLQLATLTRPGAEKT 3251
Query: 249 GINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALAT 308
G +G+ + ++ TG + L E P + ++ ++ + + T
Sbjct: 3252 GYRV-----VSGNEQGRFRLDARTGILYVNASLDFETSPKYFLSIECSRKSSSSLSDVTT 3306
Query: 309 LXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYV 368
+ QF Q YST V E A G V+LT++ ++ S + + +
Sbjct: 3307 VMVNITDVNEHRP-----QFPQDPYSTRVLENALVGDVILTVSATDEDGPL-NSDITYSL 3360
Query: 369 SDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTDS----ISNDTASINISVEDV 423
+ L F I+ GE+ + ++LD E S+Y ++ TDS + DT I I V DV
Sbjct: 3361 IGGNQLGHFTIHPKKGELQVAKALDREQASSYSLKLRATDSGQPPLHEDT-DIAIQVADV 3419
Query: 424 NEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGDAGTLALSLAGQHARMFYIN 483
N+ PRF Y +G + ++ G + F +
Sbjct: 3420 NDNPPRFFQLNYSTTVQENSPIGSKVLQLILSDPDSPENGPPYSFRIT-KGNNGSAFRVT 3478
Query: 484 ASGDLFLREEAIGNLNSSSLHLVATAIDSGIPP 516
G L + E + L A DSGIPP
Sbjct: 3479 PDGWL-VTAEGLSRRAQEWYQLQIQASDSGIPP 3510
Score = 93.9 bits (223), Expect = 2e-18
Identities = 109/435 (25%), Positives = 178/435 (40%), Gaps = 30/435 (6%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDIT--LRLQEKGAAVGIVPGSKNLTLLRALDREEK 68
+ E++P G+ + ++ D S G++ LR AA I + + L LDRE
Sbjct: 1041 VQENSPSGTQVIVVAAQDDDSGLDGELQYFLRAGTGLAAFSINQDTGMIQTLAPLDREFA 1100
Query: 69 IGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXX 128
S ++ V R + S V V + V D NDN PQ A + + E
Sbjct: 1101 ---SYYWLTVLAVDRGSVPLSSVTEVYIEVTDANDNPPQMSQAVFYPSIQEDAPVGTSVL 1157
Query: 129 XXXXSDRDQPGPHSALHYAVLPGPHSEYLGFE--NELEPIIVVKKPLDFETVNNFTIKLR 186
D D L + + G Y+GF + + ++ + LD E + +++
Sbjct: 1158 QLDAWDPDSSSK-GKLTFNITSG---NYMGFFMIHPVTGLLSTAQQLDRENKDEHILEVT 1213
Query: 187 VQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPI---SA 243
V D G P L S + + V +LD +D P F+++ + LP+ SPGP+ A
Sbjct: 1214 VLDNGEPSLKSTSRVVVGILDVNDNPPIFSHKLFNVRLPE-----RLSPVSPGPVYRLVA 1268
Query: 244 ADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDR 303
+D D G+N + YS +++ ++ TG V++ A +TI KAT P
Sbjct: 1269 SDLDEGLNGRVTYSIEDSYEEAFSIDLVTGVVSSNSTFTAGEYNILTI--KATDSGQPP- 1325
Query: 304 YALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESP 363
A++ L F + YS TV E P + ++ + +V E R
Sbjct: 1326 -LSASVRLHIEWIPWPRPSSIPLAFDETYYSFTVME-TDPVNHMVGVISV----EGRPGL 1379
Query: 364 LQFYVSDRSFLDKFAI-NNAGEVILRRSLDYETTSNYFYQVMVTDSISNDTASINI-SVE 421
F +S F I G +++ R LD SNY V VTD ++I +
Sbjct: 1380 FWFNISGGDKDMDFDIEKTTGSIVIARPLDTRRRSNYNLTVEVTDGSRTIATQVHIFMIA 1439
Query: 422 DVNEWEPRFRHPQYE 436
++N P+F +YE
Sbjct: 1440 NINHHRPQFLETRYE 1454
Score = 90.6 bits (215), Expect = 2e-17
Identities = 102/429 (23%), Positives = 172/429 (40%), Gaps = 20/429 (4%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEKIG 70
ISEDT +G+ I L+ SED G + L + P + L + LDRE +
Sbjct: 829 ISEDTEVGTTIAELTTKDADSEDNGRVRYTLLSPTEKFSLHPLTGELVVTGHLDRESE-- 886
Query: 71 PSNVY-VNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXX 129
P + V R + V + + + DVNDN+PQ ++V E
Sbjct: 887 PRYILKVEARDQPSKGHQLFSVTDLIITLEDVNDNSPQCITEHNRLKVPEDLPPGTVLTF 946
Query: 130 XXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQD 189
SD D GP + Y ++ G H + + + +++++ LDFE + + L D
Sbjct: 947 LDASDPDL-GPAGEVRYVLMDGAHGTFR--VDLMTGALILERELDFERRAGYNLSLWASD 1003
Query: 190 QGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALL-PDDAEEGTFLTTSPGPISAADQDL 248
G PL T V V+ D N H+ + + +E + T ++A D D
Sbjct: 1004 -GGRPLARRTLCHVEVI-VLDVNENLHPPHFASFVHQGQVQENSPSGTQVIVVAAQDDDS 1061
Query: 249 GINAPLQY-SSTGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALA 307
G++ LQY G +N+DTG + Q +A LD T V DR ++
Sbjct: 1062 GLDGELQYFLRAGTGLAAFSINQDTGMI----QTLAPLDREFASYYWLT-VLAVDRGSVP 1116
Query: 308 TLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFY 367
Q +Q + ++ E A G+ +L L ++ + L F
Sbjct: 1117 LSSVTEVYIEVTDANDNPPQMSQAVFYPSIQEDAPVGTSVLQLDAWDPDSS-SKGKLTFN 1175
Query: 368 VSDRSFLDKFAINN-AGEVILRRSLDYETTSNYFYQVMVTDS---ISNDTASINISVEDV 423
++ +++ F I+ G + + LD E + +V V D+ T+ + + + DV
Sbjct: 1176 ITSGNYMGFFMIHPVTGLLSTAQQLDRENKDEHILEVTVLDNGEPSLKSTSRVVVGILDV 1235
Query: 424 NEWEPRFRH 432
N+ P F H
Sbjct: 1236 NDNPPIFSH 1244
Score = 89.4 bits (212), Expect = 5e-17
Identities = 97/385 (25%), Positives = 162/385 (42%), Gaps = 36/385 (9%)
Query: 62 ALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETX 121
A DRE++ + V VR +R ++ VS+ DVNDN P+++ PY + +
Sbjct: 2027 AFDREQQ-DTHELAVEVRDNRTPQRVAQGLVRVSIE--DVNDNPPKFKHLPYYTIIQDGT 2083
Query: 122 XXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPI---IVVKKPLDFETV 178
+D D G + A+ Y +Y F ++P I +KKP D++ +
Sbjct: 2084 EPGDVLFQVSATDEDL-GTNGAVTYEFA----EDYTYFR--IDPYLGDISLKKPFDYQAL 2136
Query: 179 NNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSP 238
N + +K+ +D G+P L S+ + VTV + NP F +Y +P++ T T
Sbjct: 2137 NKYHLKVIARDGGTPSLQSEEEVLVTV--RNKSNPLFQSPYYKVRVPENI---TLYT--- 2188
Query: 239 GPISAADQDLGINAPLQYSSTGDHK-QLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQ 297
PI L Y+ + L + TG + T L E ++AT
Sbjct: 2189 -PILHTQARSPEGLRLIYNIVEEEPLMLFTTDFKTGVLTVTGPLDYESKTKHVFTVRATD 2247
Query: 298 VDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNT 357
AL + F+Q Y+T++SEG + ++ L Q++
Sbjct: 2248 T------ALGSFSEATVEVLVEDVNDNPPTFSQLVYTTSISEGLPAQTPVIQLLASDQDS 2301
Query: 358 EFRESPLQFYVSDRSFLDK-FAIN-NAGEVILRRSLDYETTSNYFYQVMVTDS----ISN 411
V D S + K F IN + GE+ + LDYE ++ +V D ++
Sbjct: 2302 GRNRDVSYQIVEDGSDVSKFFQINGSTGEMSTVQELDYEAQQHFHVKVRAMDKGDPPLTG 2361
Query: 412 DTASINISVEDVNEWEPRFRHPQYE 436
+T + ++V D+N+ P FR PQYE
Sbjct: 2362 ETLVV-VNVSDINDNPPEFRQPQYE 2385
Score = 86.6 bits (205), Expect = 3e-16
Identities = 99/429 (23%), Positives = 164/429 (38%), Gaps = 22/429 (5%)
Query: 92 IPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPG 151
+ V + V DVNDN+PQ Y +V E +D D ++ + Y+ L G
Sbjct: 2995 VTVEIFVLDVNDNSPQCSQLLYTGKVHEDVFPGHFILKVSATDLDTD-TNAQITYS-LHG 3052
Query: 152 PHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQ 211
P + + + + LD E + F + + D G +D TL V D +D
Sbjct: 3053 PGAHEFKLDPHTGELTTLTA-LDRERKDVFNLVAKATDGGGRSCQADITLHVE--DVNDN 3109
Query: 212 NPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKD 271
P+F H + D+ T + T + A D D G NA + YS + ++
Sbjct: 3110 APRFFPSHCAVAVFDN----TTVKTPVAVVFARDPDQGANAQVVYSLPDSAEGHFSIDAT 3165
Query: 272 TGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQK 331
TG + K L + + ++A+ + P L+TL F
Sbjct: 3166 TGVIRLEKPLQVRPQAPLELTVRASDLGTP--IPLSTLGTVTVSVVGLEDYLPV--FLNT 3221
Query: 332 QYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRS 390
++S V E A PG+ +L L T+ T + V + +F ++ G + + S
Sbjct: 3222 EHSVQVPEDAPPGTEVLQLATL---TRPGAEKTGYRVVSGNEQGRFRLDARTGILYVNAS 3278
Query: 391 LDYETTSNYFYQVMVTDSISN---DTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXX 447
LD+ET+ YF + + S+ D ++ +++ DVNE P+F Y
Sbjct: 3279 LDFETSPKYFLSIECSRKSSSSLSDVTTVMVNITDVNEHRPQFPQDPYSTRVLENALVGD 3338
Query: 448 XXXXXXXXXXXVAHDGDAGTLALSLAGQHARMFYINASGDLFLREEAIGNLNSSSLHLVA 507
+ D T +L + G F I+ +A+ +SS L
Sbjct: 3339 VILTVSATDEDGPLNSDI-TYSL-IGGNQLGHFTIHPKKGELQVAKALDREQASSYSLKL 3396
Query: 508 TAIDSGIPP 516
A DSG PP
Sbjct: 3397 RATDSGQPP 3405
Score = 86.2 bits (204), Expect = 5e-16
Identities = 95/436 (21%), Positives = 173/436 (39%), Gaps = 22/436 (5%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
V V V DVNDN P + Y +SE SD+D + V G
Sbjct: 2258 VEVLVEDVNDNPPTFSQLVYTTSISEGLPAQTPVIQLLASDQDSGRNRDVSYQIVEDGSD 2317
Query: 154 -SEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQN 212
S++ + V++ LD+E +F +K+R D+G PPL +T + V V D +D
Sbjct: 2318 VSKFFQINGSTGEMSTVQE-LDYEAQQHFHVKVRAMDKGDPPLTGETLVVVNVSDINDNP 2376
Query: 213 PKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQY-SSTGDHKQLIVVNKD 271
P+F Y A + + A G + + A D D + L+Y +G+ + +N
Sbjct: 2377 PEFRQPQYEANVSELATCGHLVL----KVQAIDPDSRDTSRLEYLILSGNQDRHFFINSS 2432
Query: 272 TGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQK 331
+G ++ LD S + +V D AT+ +F Q
Sbjct: 2433 SGIISMFNLCKKHLDSSYNL-----RVGASDGVFRATVPVYINTTNANKYSP---EFQQH 2484
Query: 332 QYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSL 391
Y ++E A G+ ++ L + +++ + + + ++ +KF+IN G++ + L
Sbjct: 2485 LYEAELAENAMVGTKVIDLLAIDKDSG-PYGTIDYTIINKLASEKFSINPNGQIATLQKL 2543
Query: 392 DYETTSN--YFYQVMVTDSISNDT-ASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXX 448
D E ++ +VM D ++ I + D N+ P+F+ +Y
Sbjct: 2544 DRENSTERVIAIKVMARDGGGRVAFCTVKIILTDENDNPPQFKASEYTVSIQSNVSKDSP 2603
Query: 449 XXXXXXXXXXVAHDGDAGTLALSLAGQHARMFYIN-ASGDLFLREEAIGNLNSSSLHLVA 507
+ D T +++ + IN +G + +++ +G L + +L
Sbjct: 2604 VIQVLAYDADEGQNADV-TYSVNPEDLVKDVIEINPVTGVVKVKDSLVG-LENQTLDFFI 2661
Query: 508 TAIDSGIPPRQTSVPV 523
A D G P + VPV
Sbjct: 2662 KAQDGGPPHWNSLVPV 2677
Score = 79.8 bits (188), Expect = 4e-14
Identities = 95/380 (25%), Positives = 156/380 (41%), Gaps = 22/380 (5%)
Query: 57 LTLLRALDREEKIGPSNVYV-NVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAV 115
LT+ LD E +N Y+ NV T S ++V V D NDNAP++ Y +
Sbjct: 772 LTVAAPLDYEA----TNFYILNVTVYDLGTPQKSSWKLLTVNVKDWNDNAPRFPPGGYQL 827
Query: 116 RVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDF 175
+SE D D + + Y +L P ++ + L +VV LD
Sbjct: 828 TISEDTEVGTTIAELTTKDADSE-DNGRVRYTLL-SPTEKF--SLHPLTGELVVTGHLDR 883
Query: 176 ETVNNFTIKLRVQDQGSP--PLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTF 233
E+ + +K+ +DQ S L+S T L +T+ D +D +P+ EH +P+D GT
Sbjct: 884 ESEPRYILKVEARDQPSKGHQLFSVTDLIITLEDVNDNSPQCITEHNRLKVPEDLPPGTV 943
Query: 234 LTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVL 293
LT + A+D DLG ++Y V+ TG + ++L E + L
Sbjct: 944 LTF----LDASDPDLGPAGEVRYVLMDGAHGTFRVDLMTGALILERELDFERRAGYNLSL 999
Query: 294 KATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTV 353
A+ P A TL F + V E + G+ ++ +
Sbjct: 1000 WASDGGRP--LARRTLCHVEVIVLDVNENLHPPHFASFVHQGQVQENSPSGTQVIVVAAQ 1057
Query: 354 PQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTDSISND 412
++ + LQ+++ + L F+IN + G + LD E S Y+ V+ D S
Sbjct: 1058 DDDSGL-DGELQYFLRAGTGLAAFSINQDTGMIQTLAPLDREFASYYWLTVLAVDRGSVP 1116
Query: 413 TASIN---ISVEDVNEWEPR 429
+S+ I V D N+ P+
Sbjct: 1117 LSSVTEVYIEVTDANDNPPQ 1136
Score = 79.0 bits (186), Expect = 7e-14
Identities = 59/271 (21%), Positives = 122/271 (45%), Gaps = 15/271 (5%)
Query: 166 IIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLP 225
+I V+KP+D E+ + I + + + S ++ + V D +D P F + Y A+L
Sbjct: 2748 VIKVRKPMDHESTKLYQIDVMAHCLQNTDVVSLVSVNIQVGDVNDNRPVFEADPYKAVLT 2807
Query: 226 DDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDH----KQLIVVNKDTGQVAATKQL 281
++ G TS ++A D+D G + + Y + D +L ++ ++G + ++L
Sbjct: 2808 ENMPVG----TSVIQVTAIDKDTGRDGQVSYRLSADPGSNVHELFAIDSESGWITTLQEL 2863
Query: 282 IAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGA 341
+ + T D+ L++ +F ++Y +V E +
Sbjct: 2864 --DCETCQTYHFHVVAYDHGQTIQLSS--QALVQVSITDENDNAPRFASEEYRGSVVENS 2919
Query: 342 SPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAINNAGE---VILRRSLDYETTSN 398
PG ++ TL T+ + + + Y+++ L +F I+ G+ + R++LD E T+
Sbjct: 2920 EPGELVATLKTLDADISEQNRQVTCYITEGDPLGQFGISQVGDEWRISSRKTLDREHTAK 2979
Query: 399 YFYQVMVTDSISNDTASINISVEDVNEWEPR 429
Y +V +D + ++ I V DVN+ P+
Sbjct: 2980 YLLRVTASDGKFQASVTVEIFVLDVNDNSPQ 3010
Score = 76.6 bits (180), Expect = 4e-13
Identities = 98/434 (22%), Positives = 182/434 (41%), Gaps = 41/434 (9%)
Query: 8 SFFISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREE 67
SF + E P+ ++G +SV G P L + +K I + ++ + R LD
Sbjct: 1355 SFTVMETDPVNHMVGVISVEGRPG--LFWFNISGGDKDMDFDIEKTTGSIVIARPLDTRR 1412
Query: 68 KIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVW---DVNDNAPQWEGAPYAVRVSETXXXX 124
+ SN + V TD S I V ++ ++N + PQ+ Y VRV +
Sbjct: 1413 R---SNYNLTVE-----VTDGSRTIATQVHIFMIANINHHRPQFLETRYEVRVPQDTVPG 1464
Query: 125 XXXXXXXXSDRDQ-PGPHSALHYAVLPGPHSEYLGFENELEP---IIVVKKPLDFET-VN 179
D+D+ +H + PG S + +L+P ++V LD + +
Sbjct: 1465 VELLRVQAIDQDKGKSLIYTIHGSQDPGSASLF-----QLDPSSGVLVTVGKLDLGSGPS 1519
Query: 180 NFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPG 239
T+ + V+DQ P + + + V D + P+FT HY A +PD GT L
Sbjct: 1520 QHTLTVMVRDQEIPIKRNFVWVTIHVEDGNLHPPRFTQLHYEASVPDTIAPGTELL---- 1575
Query: 240 PISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQV 298
+ A D D G+NA + YS G+ + +N G + ++L T+ +KA
Sbjct: 1576 QVRAMDADRGVNAEVHYSLLKGNSEGFFNINALLGIITLAQKLDQANHAPHTLTVKAEDQ 1635
Query: 299 DNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTE 358
+P + LAT+ F++ +Y + E GS +L ++ +
Sbjct: 1636 GSPQWHDLATVIIHVYPSDRSAPI-----FSKSEYFVEIPESIPVGSPILLVSAM----- 1685
Query: 359 FRESPLQFYVSDRSFLDKFAINN-AGEVILRRSLDYETTSNYFYQVMVTDSISNDT-ASI 416
S + + + + + F++N+ +G + ++ LD+E S+Y ++ ++ T +
Sbjct: 1686 -SPSEVTYELREGNKDGVFSMNSYSGLISTQKKLDHEKISSYQLKIRGSNMAGAFTDVMV 1744
Query: 417 NISVEDVNEWEPRF 430
+ + D N+ P F
Sbjct: 1745 VVDIIDENDNAPMF 1758
Score = 75.8 bits (178), Expect = 6e-13
Identities = 119/534 (22%), Positives = 204/534 (38%), Gaps = 42/534 (7%)
Query: 8 SFFISEDTPIGSIIGTLSVNG--DPS-EDLGDITLRLQEKGAAVGIVPGSKNLTLLRALD 64
+F ED P GS IG + DP L T K + P + + + + +D
Sbjct: 2697 TFSAPEDLPEGSEIGIVKAVAAQDPVIYSLVRGTTPESNKDGVFSLDPDTGVIKVRKPMD 2756
Query: 65 REEKIGPSNVY-VNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXX 123
E + +Y ++V + TD ++ V+++V DVNDN P +E PY ++E
Sbjct: 2757 HES----TKLYQIDVMAHCLQNTDVVSLVSVNIQVGDVNDNRPVFEADPYKAVLTENMPV 2812
Query: 124 XXXXXXXXXSDRDQPGPHSALHYAVLPGPHS---EYLGFENELEPIIVVKKPLDFETVNN 180
D+D G + Y + P S E ++E I +++ LD ET
Sbjct: 2813 GTSVIQVTAIDKD-TGRDGQVSYRLSADPGSNVHELFAIDSESGWITTLQE-LDCETCQT 2870
Query: 181 FTIKLRVQDQGSP-PLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPG 239
+ + D G L S +QV++ D +D P+F E Y + +++E G + T
Sbjct: 2871 YHFHVVAYDHGQTIQLSSQALVQVSITDENDNAPRFASEEYRGSVVENSEPGELVAT--- 2927
Query: 240 PISAADQDLG-INAPLQ-YSSTGDHKQLIVVNK--DTGQVAATKQLIAELDPSVTIVLKA 295
+ D D+ N + Y + GD +++ D ++++ K L + + + +L+
Sbjct: 2928 -LKTLDADISEQNRQVTCYITEGDPLGQFGISQVGDEWRISSRKTL--DREHTAKYLLRV 2984
Query: 296 TQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQ 355
T D + ++ Q +Q Y+ V E PG +L ++
Sbjct: 2985 TASDGKFQASVTV------EIFVLDVNDNSPQCSQLLYTGKVHEDVFPGHFILKVSATDL 3038
Query: 356 NTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSISND-TA 414
+T+ + + + + + + GE+ +LD E + TD A
Sbjct: 3039 DTD-TNAQITYSLHGPGAHEFKLDPHTGELTTLTALDRERKDVFNLVAKATDGGGRSCQA 3097
Query: 415 SINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGDAGT---LALS 471
I + VEDVN+ PRF F A D D G + S
Sbjct: 3098 DITLHVEDVNDNAPRF------FPSHCAVAVFDNTTVKTPVAVVFARDPDQGANAQVVYS 3151
Query: 472 LAGQHARMFYINASGDLFLREEAIGNLNSSSLHLVATAIDSGIP-PRQTSVPVT 524
L F I+A+ + E+ + + L L A D G P P T VT
Sbjct: 3152 LPDSAEGHFSIDATTGVIRLEKPLQVRPQAPLELTVRASDLGTPIPLSTLGTVT 3205
Score = 72.9 bits (171), Expect = 5e-12
Identities = 74/339 (21%), Positives = 133/339 (39%), Gaps = 17/339 (5%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
V+V V + D P + ++V+V E R PG Y V+ G
Sbjct: 3204 VTVSVVGLEDYLPVFLNTEHSVQVPEDAPPGTEVLQLATLTR--PGAEKT-GYRVVSGNE 3260
Query: 154 SEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNP 213
+ I+ V LDFET + + + + S L TT+ V + D ++ P
Sbjct: 3261 QGRFRLDARTG-ILYVNASLDFETSPKYFLSIECSRKSSSSLSDVTTVMVNITDVNEHRP 3319
Query: 214 KFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHK-QLIVVNKDT 272
+F + Y+ + ++A G + T +SA D+D +N+ + YS G ++ ++
Sbjct: 3320 QFPQDPYSTRVLENALVGDVILT----VSATDEDGPLNSDITYSLIGGNQLGHFTIHPKK 3375
Query: 273 GQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQ 332
G++ K L E S ++ L+AT P + + +F Q
Sbjct: 3376 GELQVAKALDREQASSYSLKLRATDSGQPPLHEDTDIAIQVADVNDNPP-----RFFQLN 3430
Query: 333 YSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLD 392
YSTTV E + GS +L L ++ P F ++ + F + G ++ L
Sbjct: 3431 YSTTVQENSPIGSKVLQLILSDPDSPENGPPYSFRITKGNNGSAFRVTPDGWLVTAEGLS 3490
Query: 393 YETTSNYFYQVMVTDS---ISNDTASINISVEDVNEWEP 428
Y Q+ +DS + S+ + V + + + P
Sbjct: 3491 RRAQEWYQLQIQASDSGIPPLSSLTSVRVHVTEQSHYAP 3529
Score = 71.7 bits (168), Expect = 1e-11
Identities = 98/438 (22%), Positives = 187/438 (42%), Gaps = 29/438 (6%)
Query: 11 ISEDTPIGS-IIGTLSVNGDPSEDLGDITLRLQEKGAA--VGIVPGSKNLTLLRALDREE 67
++E+ +G+ +I L+++ D S G I + K A+ I P + TL + LDRE
Sbjct: 2490 LAENAMVGTKVIDLLAIDKD-SGPYGTIDYTIINKLASEKFSINPNGQIATLQK-LDREN 2547
Query: 68 KIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXX 127
+ + ++ R V + + D NDN PQ++ + Y V +
Sbjct: 2548 S---TERVIAIKVMARDGGGRVAFCTVKIILTDENDNPPQFKASEYTVSIQSNVSKDSPV 2604
Query: 128 XXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRV 187
D D+ G ++ + Y+V P + + N + ++ VK L ++
Sbjct: 2605 IQVLAYDADE-GQNADVTYSVNPEDLVKDVIEINPVTGVVKVKDSLVGLENQTLDFFIKA 2663
Query: 188 QDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISA-ADQ 246
QD G P S +++ V+ PKF+ YT P+D EG+ + G + A A Q
Sbjct: 2664 QDGGPPHWNSLVPVRLQVVPKKVSLPKFSEPLYTFSAPEDLPEGSEI----GIVKAVAAQ 2719
Query: 247 DLGINAPLQYSSTGDHKQ-LIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYA 305
D I + ++ ++ +K + ++ DTG + K + E I + A + N D +
Sbjct: 2720 DPVIYSLVRGTTPESNKDGVFSLDPDTGVIKVRKPMDHESTKLYQIDVMAHCLQNTDVVS 2779
Query: 306 LATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQ 365
L ++ F Y ++E G+ ++ +T + ++T R+ +
Sbjct: 2780 LVSVNIQVGDVNDNRPV-----FEADPYKAVLTENMPVGTSVIQVTAIDKDTG-RDGQVS 2833
Query: 366 FYVS---DRSFLDKFAINN-AGEVILRRSLDYETTSNYFYQVMVTD---SIS-NDTASIN 417
+ +S + + FAI++ +G + + LD ET Y + V+ D +I + A +
Sbjct: 2834 YRLSADPGSNVHELFAIDSESGWITTLQELDCETCQTYHFHVVAYDHGQTIQLSSQALVQ 2893
Query: 418 ISVEDVNEWEPRFRHPQY 435
+S+ D N+ PRF +Y
Sbjct: 2894 VSITDENDNAPRFASEEY 2911
Score = 70.5 bits (165), Expect = 2e-11
Identities = 104/441 (23%), Positives = 183/441 (41%), Gaps = 50/441 (11%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQE--KGAAVGIVPGSKNLTLLRALDREEK 68
I E P+GS I +S PSE +T L+E K + S ++ + LD E K
Sbjct: 1669 IPESIPVGSPILLVSAMS-PSE----VTYELREGNKDGVFSMNSYSGLISTQKKLDHE-K 1722
Query: 69 IGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXX 128
I + + TD + V V + D NDNAP + + + ++SE
Sbjct: 1723 ISSYQLKIRGSNMAGAFTD----VMVVVDIIDENDNAPMFLKSTFVGQISEAAPLYSMIM 1778
Query: 129 XXX-------XSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNF 181
SD D+ +S L Y +L ++ + + + +V + +D+E++ +F
Sbjct: 1779 DKNNNPFVIHASDSDKEA-NSLLVYKILEPEALKFFKIDPSMGTLTIVSE-MDYESMPSF 1836
Query: 182 TIKLRVQDQGSPPLYSDTTLQVT--VLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPG 239
+ V DQGSP L++ QV V D +D P+F+ + Y + G L
Sbjct: 1837 QFCVYVHDQGSPVLFAPRPAQVIIHVRDVNDSPPRFSEQIYEVAIVGPIHPGMELLM--- 1893
Query: 240 PISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVD 299
+ A+D+D +N ++ TG+ + + ++ TG ++ L +TI +A+
Sbjct: 1894 -VRASDEDSEVNYSIK---TGNADEAVTIHPVTGSISVLNPAFLGLSRKLTI--RASDGL 1947
Query: 300 NPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEF 359
D AL + LQF Q Y V E L+ L Q
Sbjct: 1948 YQDT-ALVKI-------SLTQVLDKSLQFDQDVYWAAVKENLQDRKALVILGA--QGNHL 1997
Query: 360 RESPLQFYVSDRSFLDKFAINNAGEVILRR--SLDYETTSNYFYQVMVTDSISNDTAS-- 415
++ L +++ + + D F + + V+ R + D E + V V D+ + +
Sbjct: 1998 NDT-LSYFLLNGT--DMFHMVQSAGVLQTRGVAFDREQQDTHELAVEVRDNRTPQRVAQG 2054
Query: 416 -INISVEDVNEWEPRFRHPQY 435
+ +S+EDVN+ P+F+H Y
Sbjct: 2055 LVRVSIEDVNDNPPKFKHLPY 2075
Score = 70.1 bits (164), Expect = 3e-11
Identities = 82/338 (24%), Positives = 136/338 (40%), Gaps = 20/338 (5%)
Query: 95 SVRVWDVNDNAPQWEGA-PYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
S+ + +N PQ+E P ++ V E+ +D D G + L Y + G
Sbjct: 701 SLSTYQINHYTPQFEDHFPQSIDVLESVPINTPLARLAATDPDA-GFNGKLVYVIADG-- 757
Query: 154 SEYLGFENELEP-IIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQN 212
+E F+ ELE ++ V PLD+E N + + + V D G+P S L V V D +D
Sbjct: 758 NEEGCFDIELETGLLTVAAPLDYEATNFYILNVTVYDLGTPQKSSWKLLTVNVKDWNDNA 817
Query: 213 PKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDT 272
P+F Y + +D E GT + ++ D D N ++Y+ ++ ++ T
Sbjct: 818 PRFPPGGYQLTISEDTEVGTTI----AELTTKDADSEDNGRVRYTLLSPTEK-FSLHPLT 872
Query: 273 GQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQ 332
G++ T L E +P +LK D P + Q +
Sbjct: 873 GELVVTGHLDRESEP--RYILKVEARDQPSK-GHQLFSVTDLIITLEDVNDNSPQCITEH 929
Query: 333 YSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSL 391
V E PG+VL L + + + YV F ++ G +IL R L
Sbjct: 930 NRLKVPEDLPPGTVLTFLDA--SDPDLGPAGEVRYVLMDGAHGTFRVDLMTGALILEREL 987
Query: 392 DYETTSNYFYQVMVTDS---ISNDT-ASINISVEDVNE 425
D+E + Y + +D ++ T + + V DVNE
Sbjct: 988 DFERRAGYNLSLWASDGGRPLARRTLCHVEVIVLDVNE 1025
Score = 55.2 bits (127), Expect = 1e-06
Identities = 69/350 (19%), Positives = 123/350 (35%), Gaps = 27/350 (7%)
Query: 174 DFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTF 233
D E + + + V+D +P + ++V++ D +D PKF + Y ++ D E G
Sbjct: 2029 DREQQDTHELAVEVRDNRTPQRVAQGLVRVSIEDVNDNPPKFKHLPYYTIIQDGTEPGDV 2088
Query: 234 LTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVL 293
L +SA D+DLG N + Y D+ + + G ++ K + + +
Sbjct: 2089 LFQ----VSATDEDLGTNGAVTYEFAEDYTYFRI-DPYLGDISLKKPFDYQALNKYHLKV 2143
Query: 294 KATQVDNP----DRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTV-SEGASPGSVLL 348
A P + L T+ + Y+ + ++ SP + L
Sbjct: 2144 IARDGGTPSLQSEEEVLVTVRNKSNPLFQSPYYKVRVPENITLYTPILHTQARSPEGLRL 2203
Query: 349 TLTTVPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDS 408
V E PL + +D G + + LDYE+ + + + V TD+
Sbjct: 2204 IYNIV------EEEPLMLFTTDFK---------TGVLTVTGPLDYESKTKHVFTVRATDT 2248
Query: 409 I--SNDTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGDAG 466
S A++ + VEDVN+ P F Y + D
Sbjct: 2249 ALGSFSEATVEVLVEDVNDNPPTFSQLVYTTSISEGLPAQTPVIQLLASDQDSGRNRDVS 2308
Query: 467 TLALSLAGQHARMFYINASGDLFLREEAIGNLNSSSLHLVATAIDSGIPP 516
+ ++ F IN S + + H+ A+D G PP
Sbjct: 2309 YQIVEDGSDVSKFFQINGSTGEMSTVQELDYEAQQHFHVKVRAMDKGDPP 2358
>L11370-1|AAA36419.1| 1026|Homo sapiens protocadherin 42 protein.
Length = 1026
Score = 95.9 bits (228), Expect = 6e-19
Identities = 125/530 (23%), Positives = 206/530 (38%), Gaps = 39/530 (7%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVG-IVPGSKNLTLLRALDREEKI 69
+SE++PIG + + N +I + V ++ +N L+ ++
Sbjct: 255 LSENSPIGHSVIQVKANDSDQGANAEIEYTFHQAPEVVRRLLRLDRNTGLITVQGPVDRE 314
Query: 70 GPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAV--------RVSETX 121
S + +V R T S V V V D+NDNAP E + +SE
Sbjct: 315 DLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDV 374
Query: 122 XXXXXXXXXXXSDRDQPGPHSALHYAV---LPGP--HSEYLGFENELEPIIVVKKPLDFE 176
SDRD+ G ++A+ V +P + G +++ + + PLD+E
Sbjct: 375 AEETAVALVQVSDRDE-GENAAVTCVVAGDVPFQLRQASETGSDSKKKYFLQTTTPLDYE 433
Query: 177 TVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTT 236
V ++TI++ D G+PPL S +L+V V+D +D P FT P++ + G +
Sbjct: 434 KVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFPENNKPGEVI-- 491
Query: 237 SPGPISAADQDLGINAPLQYSSTGD--HKQLIVVNKDTGQVAATKQLIAELDPSVTIVLK 294
I+A+D D G NA L YS + K L ++ +TG++ L E S + +
Sbjct: 492 --AEITASDADSGSNAELVYSLEPEPAAKGLFTISPETGEIQVKTSLDREQRESYELKVV 549
Query: 295 ATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVP 354
A +P AT+ +F Y+ +V E P + + TV
Sbjct: 550 AADRGSPSLQGTATVLVNVLDCNDNDP-----KFMLSGYNFSVMEN-MPALSPVGMVTVI 603
Query: 355 QNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTD-SISNDT 413
+ + +Q V ++ D N G ++ S D E S Y +Q+ D + +
Sbjct: 604 DGDKGENAQVQLSV-EQDNGDFVIQNGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRS 662
Query: 414 A--SINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGDAGT---L 468
A + I+V D N+ P P A D D+G L
Sbjct: 663 AYVGVTINVLDENDNAPYITAP----SNTSHKLLTPQTRLGETVSQVAAEDFDSGVNAEL 718
Query: 469 ALSLAGQHA-RMFYINASGDLFLREEAIGNLNSSSLHLVATAIDSGIPPR 517
S+AG + +F I + E+ I + LV D G PPR
Sbjct: 719 IYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPR 768
Score = 83.0 bits (196), Expect = 4e-15
Identities = 98/446 (21%), Positives = 162/446 (36%), Gaps = 28/446 (6%)
Query: 96 VRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH-- 153
V V D NDNAP++E Y +SE +D DQ G ++ + Y P
Sbjct: 234 VTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQ-GANAEIEYTFHQAPEVV 292
Query: 154 SEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNP 213
L + +I V+ P+D E ++ + +D+G+ P + + VTV D +D P
Sbjct: 293 RRLLRLDRNTG-LITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAP 351
Query: 214 KFTYEHYTALLPDDA----EEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVN 269
+ D E T+ + +D+D G NA + GD +
Sbjct: 352 TIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQA 411
Query: 270 KDTGQVAATKQLIAELDP-------SVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXX 322
+TG + K + P TI + A NP + +L
Sbjct: 412 SETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPV 471
Query: 323 XXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAIN-N 381
FTQ E PG V+ +T ++ + + + F I+
Sbjct: 472 -----FTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPE 526
Query: 382 AGEVILRRSLDYETTSNYFYQVMVTDSIS---NDTASINISVEDVNEWEPRFRHPQYEFE 438
GE+ ++ SLD E +Y +V+ D S TA++ ++V D N+ +P+F Y F
Sbjct: 527 TGEIQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFS 586
Query: 439 XXXXXXXXXXXXXXXXXXXXVAHDGDAGTLALSLAGQHARMFYINASGDLFLREEAIGNL 498
G+ + LS+ + N +G + L +
Sbjct: 587 VMENMPALSPVGMVTVID---GDKGENAQVQLSVEQDNGDFVIQNGTGTI-LSSLSFDRE 642
Query: 499 NSSSLHLVATAIDSGIPPRQTSVPVT 524
S+ A+D G+PPR V VT
Sbjct: 643 QQSTYTFQLKAVDGGVPPRSAYVGVT 668
Score = 79.8 bits (188), Expect = 4e-14
Identities = 86/352 (24%), Positives = 148/352 (42%), Gaps = 30/352 (8%)
Query: 96 VRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSE 155
+ V D+NDN P + + + E SDRD GP+ Y + E
Sbjct: 134 IEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDA-GPNGVASYELQVAEDQE 192
Query: 156 YLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKF 215
E +P ++V LD E +++ + ++VQD GSPP + L+VTVLD +D PKF
Sbjct: 193 ------EKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRATSALLRVTVLDTNDNAPKF 246
Query: 216 TYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYS---STGDHKQLIVVNKDT 272
Y A L +++ G S + A D D G NA ++Y+ + ++L+ ++++T
Sbjct: 247 ERPSYEAELSENSPIG----HSVIQVKANDSDQGANAEIEYTFHQAPEVVRRLLRLDRNT 302
Query: 273 G----QVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQF 328
G Q ++ ++ L SV + T + + T+ L
Sbjct: 303 GLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTIEIRGIGL-V 361
Query: 329 TQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVS-DRSFLDKFAINNAGE--- 384
T + +SE + + L V E + + V+ D F + A +
Sbjct: 362 THQDGMANISEDVAE-ETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASETGSDSKK 420
Query: 385 -VILRRS--LDYETTSNYFYQVMVTDSIS---NDTASINISVEDVNEWEPRF 430
L+ + LDYE +Y +++ DS + + T S+ + V DVN+ P F
Sbjct: 421 KYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVF 472
Score = 35.1 bits (77), Expect = 1.1
Identities = 42/201 (20%), Positives = 81/201 (40%), Gaps = 9/201 (4%)
Query: 8 SFFISEDTPIGSIIGTLSV-NGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDRE 66
+F + E+ P S +G ++V +GD E+ + L +++ I G+ + + DRE
Sbjct: 584 NFSVMENMPALSPVGMVTVIDGDKGEN-AQVQLSVEQDNGDFVIQNGTGTILSSLSFDRE 642
Query: 67 EKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXX 126
++ S ++ S + V++ V D NDNAP T
Sbjct: 643 QQ---STYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYITAPSNTSHKLLTPQTRLG 699
Query: 127 XXXXXXSDRD-QPGPHSALHYAVLPGPHSEYLGFE-NELEPIIVVKKPLDFETVNNFTIK 184
+ D G ++ L Y++ G + Y F+ I ++K ++ +
Sbjct: 700 ETVSQVAAEDFDSGVNAELIYSIAGG--NPYGLFQIGSHSGAITLEKEIERRHHGLHRLV 757
Query: 185 LRVQDQGSPPLYSDTTLQVTV 205
++V D+G PP Y + + V
Sbjct: 758 VKVSDRGKPPRYGTALVHLYV 778
Score = 33.9 bits (74), Expect = 2.6
Identities = 49/232 (21%), Positives = 85/232 (36%), Gaps = 18/232 (7%)
Query: 202 QVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGD 261
Q+ V D +D P F T +P++ G+ P P+ A+D+D G N Y
Sbjct: 133 QIEVQDINDNTPNFASPVITLAIPENTNIGSLF---PIPL-ASDRDAGPNGVASYELQVA 188
Query: 262 HKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXX 321
Q + Q+ L E S + +K +P R A L
Sbjct: 189 EDQ----EEKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRATSALLRVTVLDTNDNAP 244
Query: 322 XXXXLQFTQKQYSTTVSEGASPG-SVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAIN 380
+F + Y +SE + G SV+ E F+ + ++
Sbjct: 245 -----KFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQAPEVVRRLLRLD 299
Query: 381 -NAGEVILRRSLDYETTSNYFYQVMVTDSISND---TASINISVEDVNEWEP 428
N G + ++ +D E S + V+ D +N A + ++V+D+N+ P
Sbjct: 300 RNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAP 351
>BC035812-1|AAH35812.1| 1060|Homo sapiens protocadherin 1 protein.
Length = 1060
Score = 95.9 bits (228), Expect = 6e-19
Identities = 125/530 (23%), Positives = 206/530 (38%), Gaps = 39/530 (7%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVG-IVPGSKNLTLLRALDREEKI 69
+SE++PIG + + N +I + V ++ +N L+ ++
Sbjct: 289 LSENSPIGHSVIQVKANDSDQGANAEIEYTFHQAPEVVRRLLRLDRNTGLITVQGPVDRE 348
Query: 70 GPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAV--------RVSETX 121
S + +V R T S V V V D+NDNAP E + +SE
Sbjct: 349 DLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDV 408
Query: 122 XXXXXXXXXXXSDRDQPGPHSALHYAV---LPGP--HSEYLGFENELEPIIVVKKPLDFE 176
SDRD+ G ++A+ V +P + G +++ + + PLD+E
Sbjct: 409 AEETAVALVQVSDRDE-GENAAVTCVVAGDVPFQLRQASETGSDSKKKYFLQTTTPLDYE 467
Query: 177 TVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTT 236
V ++TI++ D G+PPL S +L+V V+D +D P FT P++ + G +
Sbjct: 468 KVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFPENNKPGEVI-- 525
Query: 237 SPGPISAADQDLGINAPLQYSSTGD--HKQLIVVNKDTGQVAATKQLIAELDPSVTIVLK 294
I+A+D D G NA L YS + K L ++ +TG++ L E S + +
Sbjct: 526 --AEITASDADSGSNAELVYSLEPEPAAKGLFTISPETGEIQVKTSLDREQRESYELKVV 583
Query: 295 ATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVP 354
A +P AT+ +F Y+ +V E P + + TV
Sbjct: 584 AADRGSPSLQGTATVLVNVLDCNDNDP-----KFMLSGYNFSVMEN-MPALSPVGMVTVI 637
Query: 355 QNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTD-SISNDT 413
+ + +Q V ++ D N G ++ S D E S Y +Q+ D + +
Sbjct: 638 DGDKGENAQVQLSV-EQDNGDFVIQNGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRS 696
Query: 414 A--SINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGDAGT---L 468
A + I+V D N+ P P A D D+G L
Sbjct: 697 AYVGVTINVLDENDNAPYITAP----SNTSHKLLTPQTRLGETVSQVAAEDFDSGVNAEL 752
Query: 469 ALSLAGQHA-RMFYINASGDLFLREEAIGNLNSSSLHLVATAIDSGIPPR 517
S+AG + +F I + E+ I + LV D G PPR
Sbjct: 753 IYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPR 802
Score = 87.0 bits (206), Expect = 3e-16
Identities = 90/358 (25%), Positives = 154/358 (43%), Gaps = 30/358 (8%)
Query: 96 VRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSE 155
+ V D+NDN P + + + E SDRD GP+ Y + GP ++
Sbjct: 156 IEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDA-GPNGVASYELQAGPEAQ 214
Query: 156 YL-GFE-----NELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDAD 209
L G + E +P ++V LD E +++ + ++VQD GSPP S L+VTVLD +
Sbjct: 215 ELFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSALLRVTVLDTN 274
Query: 210 DQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYS---STGDHKQLI 266
D PKF Y A L +++ G S + A D D G NA ++Y+ + ++L+
Sbjct: 275 DNAPKFERPSYEAELSENSPIG----HSVIQVKANDSDQGANAEIEYTFHQAPEVVRRLL 330
Query: 267 VVNKDTG----QVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXX 322
++++TG Q ++ ++ L SV + T + + T+
Sbjct: 331 RLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTIEIR 390
Query: 323 XXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVS-DRSFLDKFAINN 381
L T + +SE + + L V E + + V+ D F + A
Sbjct: 391 GIGL-VTHQDGMANISEDVAE-ETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASET 448
Query: 382 AGE----VILRRS--LDYETTSNYFYQVMVTDSIS---NDTASINISVEDVNEWEPRF 430
+ L+ + LDYE +Y +++ DS + + T S+ + V DVN+ P F
Sbjct: 449 GSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVF 506
Score = 83.0 bits (196), Expect = 4e-15
Identities = 98/446 (21%), Positives = 162/446 (36%), Gaps = 28/446 (6%)
Query: 96 VRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH-- 153
V V D NDNAP++E Y +SE +D DQ G ++ + Y P
Sbjct: 268 VTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQ-GANAEIEYTFHQAPEVV 326
Query: 154 SEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNP 213
L + +I V+ P+D E ++ + +D+G+ P + + VTV D +D P
Sbjct: 327 RRLLRLDRNTG-LITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAP 385
Query: 214 KFTYEHYTALLPDDA----EEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVN 269
+ D E T+ + +D+D G NA + GD +
Sbjct: 386 TIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQA 445
Query: 270 KDTGQVAATKQLIAELDP-------SVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXX 322
+TG + K + P TI + A NP + +L
Sbjct: 446 SETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPV 505
Query: 323 XXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAIN-N 381
FTQ E PG V+ +T ++ + + + F I+
Sbjct: 506 -----FTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPE 560
Query: 382 AGEVILRRSLDYETTSNYFYQVMVTDSIS---NDTASINISVEDVNEWEPRFRHPQYEFE 438
GE+ ++ SLD E +Y +V+ D S TA++ ++V D N+ +P+F Y F
Sbjct: 561 TGEIQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFS 620
Query: 439 XXXXXXXXXXXXXXXXXXXXVAHDGDAGTLALSLAGQHARMFYINASGDLFLREEAIGNL 498
G+ + LS+ + N +G + L +
Sbjct: 621 VMENMPALSPVGMVTVID---GDKGENAQVQLSVEQDNGDFVIQNGTGTI-LSSLSFDRE 676
Query: 499 NSSSLHLVATAIDSGIPPRQTSVPVT 524
S+ A+D G+PPR V VT
Sbjct: 677 QQSTYTFQLKAVDGGVPPRSAYVGVT 702
Score = 35.1 bits (77), Expect = 1.1
Identities = 42/201 (20%), Positives = 81/201 (40%), Gaps = 9/201 (4%)
Query: 8 SFFISEDTPIGSIIGTLSV-NGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDRE 66
+F + E+ P S +G ++V +GD E+ + L +++ I G+ + + DRE
Sbjct: 618 NFSVMENMPALSPVGMVTVIDGDKGEN-AQVQLSVEQDNGDFVIQNGTGTILSSLSFDRE 676
Query: 67 EKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXX 126
++ S ++ S + V++ V D NDNAP T
Sbjct: 677 QQ---STYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYITAPSNTSHKLLTPQTRLG 733
Query: 127 XXXXXXSDRD-QPGPHSALHYAVLPGPHSEYLGFE-NELEPIIVVKKPLDFETVNNFTIK 184
+ D G ++ L Y++ G + Y F+ I ++K ++ +
Sbjct: 734 ETVSQVAAEDFDSGVNAELIYSIAGG--NPYGLFQIGSHSGAITLEKEIERRHHGLHRLV 791
Query: 185 LRVQDQGSPPLYSDTTLQVTV 205
++V D+G PP Y + + V
Sbjct: 792 VKVSDRGKPPRYGTALVHLYV 812
Score = 34.3 bits (75), Expect = 2.0
Identities = 56/251 (22%), Positives = 96/251 (38%), Gaps = 25/251 (9%)
Query: 191 GSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGI 250
GSP L Q+ V D +D P F T +P++ G+ P P+ A+D+D G
Sbjct: 147 GSPRLLEG---QIEVQDINDNTPNFASPVITLAIPENTNIGSLF---PIPL-ASDRDAGP 199
Query: 251 NAPLQY--SSTGDHKQLIVVNKDTGQVAATKQLI--AELD----PSVTIVLKATQVDNPD 302
N Y + + ++L + Q QLI LD S + +K +P
Sbjct: 200 NGVASYELQAGPEAQELFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPP 259
Query: 303 RYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPG-SVLLTLTTVPQNTEFRE 361
R + A L +F + Y +SE + G SV+ E
Sbjct: 260 RASSALLRVTVLDTNDNAP-----KFERPSYEAELSENSPIGHSVIQVKANDSDQGANAE 314
Query: 362 SPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTDSISND---TASIN 417
F+ + ++ N G + ++ +D E S + V+ D +N A +
Sbjct: 315 IEYTFHQAPEVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVV 374
Query: 418 ISVEDVNEWEP 428
++V+D+N+ P
Sbjct: 375 VTVKDMNDNAP 385
Score = 33.1 bits (72), Expect = 4.5
Identities = 19/58 (32%), Positives = 30/58 (51%), Gaps = 3/58 (5%)
Query: 384 EVILRRSLDYETTSNYFYQVMVTDSISNDTAS---INISVEDVNEWEPRFRHPQYEFE 438
++I+ +LD E +Y + V D S AS + ++V D N+ P+F P YE E
Sbjct: 231 QLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSALLRVTVLDTNDNAPKFERPSYEAE 288
>AJ007611-1|CAC13127.1| 784|Homo sapiens cadherin-7 protein.
Length = 784
Score = 95.9 bits (228), Expect = 6e-19
Identities = 106/444 (23%), Positives = 192/444 (43%), Gaps = 37/444 (8%)
Query: 9 FFISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAA-VGIVP-GSKNLTLLRALDRE 66
FF+ E+ + ++ D + G I L +GA+ + I+ + ++ + LDRE
Sbjct: 54 FFVLEEYMGSDPLYVGKLHSDVDKGDGSIKYILSGEGASSIFIIDENTGDIHATKRLDRE 113
Query: 67 EKIGPSNVYVNVRCDR--RRTTDPSFVIPVS---VRVWDVNDNAPQWEGAPYAVRVSETX 121
E+ Y +R R T P V P S +++ D+NDN P++ PY V E
Sbjct: 114 EQ-----AYYTLRAQALDRLTNKP--VEPESEFVIKIQDINDNEPKFLDGPYTAGVPEMS 166
Query: 122 XXXXXXXXXXXSDRDQP--GPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVN 179
+D D P G + + Y++L G Y E + I +D E +
Sbjct: 167 PVGTSVVQVTATDADDPTYGNSARVVYSILQG--QPYFSVEPKTGVIKTALPNMDREAKD 224
Query: 180 NFTIKLRVQDQ--GSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTS 237
+ + ++ +D + L T++ VT+ D +D P+F Y +P+ + +
Sbjct: 225 QYLLVIQAKDMVGQNGGLSGTTSVTVTLTDVNDNPPRFPRRSYQYNVPESLPVASVVAR- 283
Query: 238 PGPISAADQDLGINAPLQYSST-GDHKQL--IVVNKDT--GQVAATKQLIAELDPSVTIV 292
I AAD D+G NA ++Y GD + I V+K+T G + K+L E S T+
Sbjct: 284 ---IKAADADIGANAEMEYKIVDGDGLGIFKISVDKETQEGIITIQKELDFEAKTSYTLR 340
Query: 293 LKATQVDNPDRY-ALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLT 351
++A D R+ +L F+ Y VSE G+++ T+
Sbjct: 341 IEAANKDADPRFLSLGPFSDTTTVKIIVEDVDEPPVFSSPLYPMEVSEATQVGNIIGTVA 400
Query: 352 TVPQNTEFRESPLQFYVSDRSFLDK-FAIN-NAGEVILRRSLDYETTSNYFYQVMVTDSI 409
+ + SP+++ + + L++ F I+ N+G + +SLD ET + + V+ +S
Sbjct: 401 A--HDPDSSNSPVRYSIDRNTDLERYFNIDANSGVITTAKSLDRETNAIHNITVLAMESQ 458
Query: 410 SNDTAS---INISVEDVNEWEPRF 430
+ + I++ D+N+ P F
Sbjct: 459 NPSQVGRGYVAITILDINDNAPEF 482
Score = 82.2 bits (194), Expect = 7e-15
Identities = 84/349 (24%), Positives = 153/349 (43%), Gaps = 32/349 (9%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
V+V + DVNDN P++ Y V E+ +D D G ++ + Y ++ G
Sbjct: 248 VTVTLTDVNDNPPRFPRRSYQYNVPESLPVASVVARIKAADADI-GANAEMEYKIVDGDG 306
Query: 154 SEY--LGFENEL-EPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLY------SDTTLQVT 204
+ + E E II ++K LDFE ++T+++ ++ + P + SDTT
Sbjct: 307 LGIFKISVDKETQEGIITIQKELDFEAKTSYTLRIEAANKDADPRFLSLGPFSDTTTVKI 366
Query: 205 VLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYS--STGDH 262
+++ D+ P F+ + L P + E T + G ++A D D N+P++YS D
Sbjct: 367 IVEDVDEPPVFS----SPLYPMEVSEATQVGNIIGTVAAHDPDSS-NSPVRYSIDRNTDL 421
Query: 263 KQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXX 322
++ ++ ++G + K L E + I + A + NP + +
Sbjct: 422 ERYFNIDANSGVITTAKSLDRETNAIHNITVLAMESQNPSQVGRGYVAITILDINDNAP- 480
Query: 323 XXXLQFTQKQYSTTVSEGASPGSVLLTLTTV----PQN-TEFRESPLQFYVSDRSFLDKF 377
+F Y TTV E A PG V+ ++ V P N +F S ++ +F K
Sbjct: 481 ----EFAM-DYETTVCENAQPGQVIQKISAVDKDEPSNGHQFYFSLTTDATNNHNFSLKD 535
Query: 378 AINNAGEVILRRS-LDYETTSNYFYQVMVTDSIS---NDTASINISVED 422
+N ++ RR+ + S Y+ + + DS S + T+++ I V D
Sbjct: 536 NKDNTASILTRRNGFRRQEQSVYYLPIFIVDSGSPSLSSTSTLTIRVCD 584
Score = 50.4 bits (115), Expect = 3e-05
Identities = 47/208 (22%), Positives = 88/208 (42%), Gaps = 16/208 (7%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAA---VGIVPGSKNLTLLRALDREE 67
+SE T +G+IIGT++ + DP + + I S +T ++LDRE
Sbjct: 386 VSEATQVGNIIGTVAAH-DPDSSNSPVRYSIDRNTDLERYFNIDANSGVITTAKSLDRE- 443
Query: 68 KIGPSNVYVNVRCDRRRTTDPSFVIP--VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXX 125
+N N+ + +PS V V++ + D+NDNAP++ Y V E
Sbjct: 444 ----TNAIHNITVLAMESQNPSQVGRGYVAITILDINDNAPEF-AMDYETTVCENAQPGQ 498
Query: 126 XXXXXXXSDRDQPGPHSALHYAVLPGPHSEY----LGFENELEPIIVVKKPLDFETVNNF 181
D+D+P ++++ + + ++ I+ + + + +
Sbjct: 499 VIQKISAVDKDEPSNGHQFYFSLTTDATNNHNFSLKDNKDNTASILTRRNGFRRQEQSVY 558
Query: 182 TIKLRVQDQGSPPLYSDTTLQVTVLDAD 209
+ + + D GSP L S +TL + V D D
Sbjct: 559 YLPIFIVDSGSPSLSSTSTLTIRVCDCD 586
>AJ007608-1|CAC22255.1| 963|Homo sapiens protocadherin alpha-C1
protein.
Length = 963
Score = 95.9 bits (228), Expect = 6e-19
Identities = 102/437 (23%), Positives = 170/437 (38%), Gaps = 18/437 (4%)
Query: 9 FFISEDTPIGSIIGTLSVNGD-PSEDLGDITLRL--QEKGAAVGIVPGSKNLTLLRALDR 65
+ + E+T G +G LS + P+ + R + G+ S NL + DR
Sbjct: 24 YSVPEETERGVAVGNLSADLRLPAAAMSSRNFRFLSSHRELYFGVDLPSGNLVVREPADR 83
Query: 66 EEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXX 125
E+ V + D DP + + + V D NDN+P + + + E
Sbjct: 84 EQLCRAKAACV-LTYDLV-LEDPLELHKIRIHVLDTNDNSPLFPAGDVQLHIPEFLTPGA 141
Query: 126 XXXXXXXSDRDQPGPHSALHYAVLPGPHSEY-LG--FENELEPIIVVKKPLDFETVNNFT 182
D D+ G + L Y++ P H +G + P +V++K LD E
Sbjct: 142 RFTLPNAQDDDE-GSNGILSYSLSPSQHFRLDMGSRVDGSEYPELVLEKALDREQRATHL 200
Query: 183 IKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPIS 242
+ L +D G P D + + V+D +D P F Y +P+ A GT L +
Sbjct: 201 LVLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYRTKVPETAPNGTVLFR----VQ 256
Query: 243 AADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPD 302
A D D G N +QYS + + + + Q+ A L P T++ + +
Sbjct: 257 ALDPDEGSNGEVQYSLSNSTQAELRHRFHVHPKSGEVQVAASLGPPETLLEAYIEARDEG 316
Query: 303 RYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRES 362
+ LA+ L F S V E A+PG+V+ + ++ +
Sbjct: 317 VFGLASTAKLLVEVTDVNDHAPELDFL--TLSNPVPEDAAPGTVIALFSVKDEDLDSNGR 374
Query: 363 PLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSIS---NDTASINIS 419
+ S F + +N +++ LD E S Y + +DS S + +I +S
Sbjct: 375 VICGMSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLITASDSGSPPLSTRRTITVS 434
Query: 420 VEDVNEWEPRFRHPQYE 436
V DVN+ P F PQ E
Sbjct: 435 VADVNDNTPNFPQPQQE 451
Score = 62.5 bits (145), Expect = 6e-09
Identities = 43/161 (26%), Positives = 66/161 (40%), Gaps = 6/161 (3%)
Query: 96 VRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSE 155
V V DVND+AP+ + + V E D D + GP
Sbjct: 328 VEVTDVNDHAPELDFLTLSNPVPEDAAPGTVIALFSVKDEDLDSNGRVICGMSSAGPFQL 387
Query: 156 YLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKF 215
F+N +++ PLD E ++ + + + D GSPPL + T+ V+V D +D P F
Sbjct: 388 TASFDNYYS--LLIDGPLDREQISEYQVLITASDSGSPPLSTRRTITVSVADVNDNTPNF 445
Query: 216 TYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQY 256
+ ++ G L G + A D DLG N + Y
Sbjct: 446 PQPQQELFVAENNGPGPPL----GRVFAQDPDLGKNGLVSY 482
Score = 54.4 bits (125), Expect = 2e-06
Identities = 68/289 (23%), Positives = 109/289 (37%), Gaps = 22/289 (7%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLL--RALDREEK 68
+ ED G++I SV + + G + + G +LL LDRE+
Sbjct: 349 VPEDAAPGTVIALFSVKDEDLDSNGRVICGMSSAGPFQLTASFDNYYSLLIDGPLDREQI 408
Query: 69 IGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXX 128
S V + + S ++V V DVNDN P + + V+E
Sbjct: 409 ---SEYQVLITASDSGSPPLSTRRTITVSVADVNDNTPNFPQPQQELFVAENNGPGPPLG 465
Query: 129 XXXXSDRDQPGPHSALHYAVLP----GPHSEYLGFENELEPIIVVKKPLDFETVNNFTIK 184
D D G + + Y +L GP + L I K DFE + F +
Sbjct: 466 RVFAQDPDL-GKNGLVSYELLDVISEGPSASSLLAVESSSGAITAKTSFDFEQLRGFHFQ 524
Query: 185 LRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTY------EHYTALLPDDAEEGTFLTTSP 238
+ +D G PP + T+ + V+D +D P + ++P A G +T
Sbjct: 525 VEGRDGGIPPRSATVTINLFVVDRNDNYPVILFPLPRNGSVPVEIVPRSARTGHLVT--- 581
Query: 239 GPISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELD 286
+ A D D G NA L Y S L ++ + G++ T +L+ D
Sbjct: 582 -KVVAEDADSGSNAWLSYHISRASDSSLFRISANIGEL-RTARLVLPTD 628
Score = 37.1 bits (82), Expect = 0.28
Identities = 79/339 (23%), Positives = 127/339 (37%), Gaps = 31/339 (9%)
Query: 201 LQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYS-ST 259
+++ VLD +D +P F +P+ G T +A D D G N L YS S
Sbjct: 110 IRIHVLDTNDNSPLFPAGDVQLHIPEFLTPGARFTLP----NAQDDDEGSNGILSYSLSP 165
Query: 260 GDHKQLIVVNKDTG----QVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXX 315
H +L + ++ G ++ K L E + +VL A P R A +
Sbjct: 166 SQHFRLDMGSRVDGSEYPELVLEKALDREQRATHLLVLTARDGGLPARSGDAQVTIIVVD 225
Query: 316 XXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLD 375
F + Y T V E A G+VL + + + E +Q+ +S+ + +
Sbjct: 226 TNDNAPV-----FERSVYRTKVPETAPNGTVLFRVQALDPD-EGSNGEVQYSLSNSTQAE 279
Query: 376 ---KFAIN-NAGEVILRRSLDYETTSNYFYQVMVTDSISN--DTASINISVEDVNEWEPR 429
+F ++ +GEV + SL T Y + + TA + + V DVN+
Sbjct: 280 LRHRFHVHPKSGEVQVAASLGPPETLLEAYIEARDEGVFGLASTAKLLVEVTDVND---- 335
Query: 430 FRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGDAGTLALSLAGQH-ARMFYINASGDL 488
P+ +F V D D + + G A F + AS D
Sbjct: 336 -HAPELDFLTLSNPVPEDAAPGTVIALFSVK-DEDLDSNGRVICGMSSAGPFQLTASFDN 393
Query: 489 FLREEAIGNLNS---SSLHLVATAIDSGIPPRQTSVPVT 524
+ G L+ S ++ TA DSG PP T +T
Sbjct: 394 YYSLLIDGPLDREQISEYQVLITASDSGSPPLSTRRTIT 432
>AB035301-1|BAA87415.1| 785|Homo sapiens cadherin-7 protein.
Length = 785
Score = 95.9 bits (228), Expect = 6e-19
Identities = 106/444 (23%), Positives = 192/444 (43%), Gaps = 37/444 (8%)
Query: 9 FFISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAA-VGIVP-GSKNLTLLRALDRE 66
FF+ E+ + ++ D + G I L +GA+ + I+ + ++ + LDRE
Sbjct: 54 FFVLEEYMGSDPLYVGKLHSDVDKGDGSIKYILSGEGASSIFIIDENTGDIHATKRLDRE 113
Query: 67 EKIGPSNVYVNVRCDR--RRTTDPSFVIPVS---VRVWDVNDNAPQWEGAPYAVRVSETX 121
E+ Y +R R T P V P S +++ D+NDN P++ PY V E
Sbjct: 114 EQ-----AYYTLRAQALDRLTNKP--VEPESEFVIKIQDINDNEPKFLDGPYTAGVPEMS 166
Query: 122 XXXXXXXXXXXSDRDQP--GPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVN 179
+D D P G + + Y++L G Y E + I +D E +
Sbjct: 167 PVGTSVVQVTATDADDPTYGNSARVVYSILQG--QPYFSVEPKTGVIKTALPNMDREAKD 224
Query: 180 NFTIKLRVQDQ--GSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTS 237
+ + ++ +D + L T++ VT+ D +D P+F Y +P+ + +
Sbjct: 225 QYLLVIQAKDMVGQNGGLSGTTSVTVTLTDVNDNPPRFPRRSYQYNVPESLPVASVVAR- 283
Query: 238 PGPISAADQDLGINAPLQYSST-GDHKQL--IVVNKDT--GQVAATKQLIAELDPSVTIV 292
I AAD D+G NA ++Y GD + I V+K+T G + K+L E S T+
Sbjct: 284 ---IKAADADIGANAEMEYKIVDGDGLGIFKISVDKETQEGIITIQKELDFEAKTSYTLR 340
Query: 293 LKATQVDNPDRY-ALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLT 351
++A D R+ +L F+ Y VSE G+++ T+
Sbjct: 341 IEAANKDADPRFLSLGPFSDTTTVKIIVEDVDEPPVFSSPLYPMEVSEATQVGNIIGTVA 400
Query: 352 TVPQNTEFRESPLQFYVSDRSFLDK-FAIN-NAGEVILRRSLDYETTSNYFYQVMVTDSI 409
+ + SP+++ + + L++ F I+ N+G + +SLD ET + + V+ +S
Sbjct: 401 A--HDPDSSNSPVRYSIDRNTDLERYFNIDANSGVITTAKSLDRETNAIHNITVLAMESQ 458
Query: 410 SNDTAS---INISVEDVNEWEPRF 430
+ + I++ D+N+ P F
Sbjct: 459 NPSQVGRGYVAITILDINDNAPEF 482
Score = 82.2 bits (194), Expect = 7e-15
Identities = 84/349 (24%), Positives = 153/349 (43%), Gaps = 32/349 (9%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
V+V + DVNDN P++ Y V E+ +D D G ++ + Y ++ G
Sbjct: 248 VTVTLTDVNDNPPRFPRRSYQYNVPESLPVASVVARIKAADADI-GANAEMEYKIVDGDG 306
Query: 154 SEY--LGFENEL-EPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLY------SDTTLQVT 204
+ + E E II ++K LDFE ++T+++ ++ + P + SDTT
Sbjct: 307 LGIFKISVDKETQEGIITIQKELDFEAKTSYTLRIEAANKDADPRFLSLGPFSDTTTVKI 366
Query: 205 VLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYS--STGDH 262
+++ D+ P F+ + L P + E T + G ++A D D N+P++YS D
Sbjct: 367 IVEDVDEPPVFS----SPLYPMEVSEATQVGNIIGTVAAHDPDSS-NSPVRYSIDRNTDL 421
Query: 263 KQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXX 322
++ ++ ++G + K L E + I + A + NP + +
Sbjct: 422 ERYFNIDANSGVITTAKSLDRETNAIHNITVLAMESQNPSQVGRGYVAITILDINDNAP- 480
Query: 323 XXXLQFTQKQYSTTVSEGASPGSVLLTLTTV----PQN-TEFRESPLQFYVSDRSFLDKF 377
+F Y TTV E A PG V+ ++ V P N +F S ++ +F K
Sbjct: 481 ----EFAM-DYETTVCENAQPGQVIQKISAVDKDEPSNGHQFYFSLTTDATNNHNFSLKD 535
Query: 378 AINNAGEVILRRS-LDYETTSNYFYQVMVTDSIS---NDTASINISVED 422
+N ++ RR+ + S Y+ + + DS S + T+++ I V D
Sbjct: 536 NKDNTASILTRRNGFRRQEQSVYYLPIFIVDSGSPSLSSTSTLTIRVCD 584
Score = 52.0 bits (119), Expect = 9e-06
Identities = 51/233 (21%), Positives = 94/233 (40%), Gaps = 16/233 (6%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAA---VGIVPGSKNLTLLRALDREE 67
+SE T +G+IIGT++ + DP + + I S +T ++LDRE
Sbjct: 386 VSEATQVGNIIGTVAAH-DPDSSNSPVRYSIDRNTDLERYFNIDANSGVITTAKSLDRE- 443
Query: 68 KIGPSNVYVNVRCDRRRTTDPSFVIP--VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXX 125
+N N+ + +PS V V++ + D+NDNAP++ Y V E
Sbjct: 444 ----TNAIHNITVLAMESQNPSQVGRGYVAITILDINDNAPEF-AMDYETTVCENAQPGQ 498
Query: 126 XXXXXXXSDRDQPGPHSALHYAVLPGPHSEY----LGFENELEPIIVVKKPLDFETVNNF 181
D+D+P ++++ + + ++ I+ + + + +
Sbjct: 499 VIQKISAVDKDEPSNGHQFYFSLTTDATNNHNFSLKDNKDNTASILTRRNGFRRQEQSVY 558
Query: 182 TIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFL 234
+ + + D GSP L S +TL + V D D T +LP G +
Sbjct: 559 YLPIFIVDSGSPSLSSTSTLTIRVCDCDADGVAQTCNAEAYVLPAGLSTGALI 611
>BC113372-1|AAI13373.1| 792|Homo sapiens protocadherin alpha 12
protein.
Length = 792
Score = 95.5 bits (227), Expect = 7e-19
Identities = 115/476 (24%), Positives = 190/476 (39%), Gaps = 33/476 (6%)
Query: 63 LDREEKIGPS---NVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSE 119
+DRE+ G S ++++ V DR P V V V V D+NDN P + V VSE
Sbjct: 90 IDREKLCGRSAECSIHLEVIVDR-----PLQVFHVDVEVKDINDNPPVFREREQKVPVSE 144
Query: 120 TXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEY---LGFENELEPIIVVKKPLDFE 176
+ SD D G +S L YA+ + E + + P +V++K LD E
Sbjct: 145 SAPLDSHFPLEGASDADI-GVNSLLTYALSLNENFELKIKTKKDKSILPELVLRKLLDRE 203
Query: 177 TVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTT 236
+ L V D G P L +Q+TVLD +D P F Y +L ++ + T +
Sbjct: 204 QTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPAFDKPSYKVVLSENVQNDTRVIQ 263
Query: 237 SPGPISAADQDLGINAPLQYSSTG----DHKQLIVVNKDTGQVAATKQLIAELDPSVTIV 292
++A+D D G+N + Y K + +N DTG++ +L E + + I
Sbjct: 264 ----LNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGEIRIYGELDFEENNAYEIQ 319
Query: 293 LKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTT 352
+ A P ++A + T S V E A G+V+ ++
Sbjct: 320 VNAIDKGIP---SMAGHSMVLVEVLDVNDNVPEVMVTS--LSLPVQEDAQVGTVIALISV 374
Query: 353 VPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSISND 412
+++ + F N ++L +LD E+ S Y V D S
Sbjct: 375 SDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTARDGGSPS 434
Query: 413 ---TASINISVEDVNEWEPRFRHPQYE-FEXXXXXXXXXXXXXXXXXXXXVAHDGDAGTL 468
TA +++ V DVN+ P F P+Y F + + +L
Sbjct: 435 LWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQKNALVSYSL 494
Query: 469 ALSLAGQHARMFYINASGDLFLREEAIGNLNSSSLHLV---ATAIDSGIPPRQTSV 521
G+HA Y++ + + A+ L+ L L+ +A D+G+PP ++V
Sbjct: 495 VERRVGEHALSSYVSVHAESG-KVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549
Score = 65.7 bits (153), Expect = 7e-10
Identities = 83/292 (28%), Positives = 120/292 (41%), Gaps = 34/292 (11%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKN---LTLLRALDREE 67
+ ED +G++I +SV+ S G + L +V KN L L ALDRE
Sbjct: 359 VQEDAQVGTVIALISVSDRDSGANGQVICSLTPH-VPFKLVSTYKNYYSLVLDSALDRES 417
Query: 68 KIGPSNVYVNVRCDRRRTTDPSF--VIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXX 125
+ + V R PS VSV V DVNDNAP + Y V V E
Sbjct: 418 -VSAYELVVTARDGG----SPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGC 472
Query: 126 XXXXXXXSDRDQPGPHSALHYAVLP---GPH--SEYLGFENELEPIIVVKKPLDFETVNN 180
D D ++ + Y+++ G H S Y+ E + ++ PLD E +
Sbjct: 473 HIFTVSAWDADAQ-KNALVSYSLVERRVGEHALSSYVSVHAESGKVYALQ-PLDHEELEL 530
Query: 181 FTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYE-------HYTALLPDDAEEGTF 233
++ +D G PPL S+ TLQV VLD +D P + L+P G
Sbjct: 531 LQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHV 590
Query: 234 LTTSPGPISAADQDLGINAPLQY----SSTGDHKQLIVVNKDTGQVAATKQL 281
+ + A D D G NA L Y ++ G H V TG+++ T+ L
Sbjct: 591 V----AKVRAVDADSGYNAWLSYELQPAAVGAHIP-FHVGLYTGEISTTRIL 637
>BC112280-1|AAI12281.1| 792|Homo sapiens protocadherin alpha 12,
isoform 2 precursor protein.
Length = 792
Score = 95.5 bits (227), Expect = 7e-19
Identities = 115/476 (24%), Positives = 190/476 (39%), Gaps = 33/476 (6%)
Query: 63 LDREEKIGPS---NVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSE 119
+DRE+ G S ++++ V DR P V V V V D+NDN P + V VSE
Sbjct: 90 IDREKLCGRSAECSIHLEVIVDR-----PLQVFHVDVEVKDINDNPPVFREREQKVPVSE 144
Query: 120 TXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEY---LGFENELEPIIVVKKPLDFE 176
+ SD D G +S L YA+ + E + + P +V++K LD E
Sbjct: 145 SAPLDSHFPLEGASDADI-GVNSLLTYALSLNENFELKIKTKKDKSILPELVLRKLLDRE 203
Query: 177 TVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTT 236
+ L V D G P L +Q+TVLD +D P F Y +L ++ + T +
Sbjct: 204 QTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPAFDKPSYKVVLSENVQNDTRVIQ 263
Query: 237 SPGPISAADQDLGINAPLQYSSTG----DHKQLIVVNKDTGQVAATKQLIAELDPSVTIV 292
++A+D D G+N + Y K + +N DTG++ +L E + + I
Sbjct: 264 ----LNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGEIRIYGELDFEENNAYEIQ 319
Query: 293 LKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTT 352
+ A P ++A + T S V E A G+V+ ++
Sbjct: 320 VNAIDKGIP---SMAGHSMVLVEVLDVNDNVPEVMVTS--LSLPVQEDAQVGTVIALISV 374
Query: 353 VPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSISND 412
+++ + F N ++L +LD E+ S Y V D S
Sbjct: 375 SDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTARDGGSPS 434
Query: 413 ---TASINISVEDVNEWEPRFRHPQYE-FEXXXXXXXXXXXXXXXXXXXXVAHDGDAGTL 468
TA +++ V DVN+ P F P+Y F + + +L
Sbjct: 435 LWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQKNALVSYSL 494
Query: 469 ALSLAGQHARMFYINASGDLFLREEAIGNLNSSSLHLV---ATAIDSGIPPRQTSV 521
G+HA Y++ + + A+ L+ L L+ +A D+G+PP ++V
Sbjct: 495 VERRVGEHALSSYVSVHAESG-KVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549
Score = 65.7 bits (153), Expect = 7e-10
Identities = 83/292 (28%), Positives = 120/292 (41%), Gaps = 34/292 (11%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKN---LTLLRALDREE 67
+ ED +G++I +SV+ S G + L +V KN L L ALDRE
Sbjct: 359 VQEDAQVGTVIALISVSDRDSGANGQVICSLTPH-VPFKLVSTYKNYYSLVLDSALDRES 417
Query: 68 KIGPSNVYVNVRCDRRRTTDPSF--VIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXX 125
+ + V R PS VSV V DVNDNAP + Y V V E
Sbjct: 418 -VSAYELVVTARDGG----SPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGC 472
Query: 126 XXXXXXXSDRDQPGPHSALHYAVLP---GPH--SEYLGFENELEPIIVVKKPLDFETVNN 180
D D ++ + Y+++ G H S Y+ E + ++ PLD E +
Sbjct: 473 HIFTVSAWDADAQ-KNALVSYSLVERRVGEHALSSYVSVHAESGKVYALQ-PLDHEELEL 530
Query: 181 FTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYE-------HYTALLPDDAEEGTF 233
++ +D G PPL S+ TLQV VLD +D P + L+P G
Sbjct: 531 LQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHV 590
Query: 234 LTTSPGPISAADQDLGINAPLQY----SSTGDHKQLIVVNKDTGQVAATKQL 281
+ + A D D G NA L Y ++ G H V TG+++ T+ L
Sbjct: 591 V----AKVRAVDADSGYNAWLSYELQPAAVGAHIP-FHVGLYTGEISTTRIL 637
>AF152477-1|AAD43738.1| 792|Homo sapiens protocadherin alpha 12
short form protein protein.
Length = 792
Score = 95.5 bits (227), Expect = 7e-19
Identities = 115/476 (24%), Positives = 190/476 (39%), Gaps = 33/476 (6%)
Query: 63 LDREEKIGPS---NVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSE 119
+DRE+ G S ++++ V DR P V V V V D+NDN P + V VSE
Sbjct: 90 IDREKLCGRSAECSIHLEVIVDR-----PLQVFHVDVEVKDINDNPPVFREREQKVPVSE 144
Query: 120 TXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEY---LGFENELEPIIVVKKPLDFE 176
+ SD D G +S L YA+ + E + + P +V++K LD E
Sbjct: 145 SAPLDSHFPLEGASDADI-GVNSLLTYALSLNENFELKIKTKKDKSILPELVLRKLLDRE 203
Query: 177 TVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTT 236
+ L V D G P L +Q+TVLD +D P F Y +L ++ + T +
Sbjct: 204 QTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPAFDKPSYKVVLSENVQNDTRVIQ 263
Query: 237 SPGPISAADQDLGINAPLQYSSTG----DHKQLIVVNKDTGQVAATKQLIAELDPSVTIV 292
++A+D D G+N + Y K + +N DTG++ +L E + + I
Sbjct: 264 ----LNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGEIRIYGELDFEENNAYEIQ 319
Query: 293 LKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTT 352
+ A P ++A + T S V E A G+V+ ++
Sbjct: 320 VNAIDKGIP---SMAGHSMVLVEVLDVNDNVPEVMVTS--LSLPVQEDAQVGTVIALISV 374
Query: 353 VPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSISND 412
+++ + F N ++L +LD E+ S Y V D S
Sbjct: 375 SDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTARDGGSPS 434
Query: 413 ---TASINISVEDVNEWEPRFRHPQYE-FEXXXXXXXXXXXXXXXXXXXXVAHDGDAGTL 468
TA +++ V DVN+ P F P+Y F + + +L
Sbjct: 435 LWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQKNALVSYSL 494
Query: 469 ALSLAGQHARMFYINASGDLFLREEAIGNLNSSSLHLV---ATAIDSGIPPRQTSV 521
G+HA Y++ + + A+ L+ L L+ +A D+G+PP ++V
Sbjct: 495 VERRVGEHALSSYVSVHAESG-KVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549
Score = 65.7 bits (153), Expect = 7e-10
Identities = 83/292 (28%), Positives = 120/292 (41%), Gaps = 34/292 (11%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKN---LTLLRALDREE 67
+ ED +G++I +SV+ S G + L +V KN L L ALDRE
Sbjct: 359 VQEDAQVGTVIALISVSDRDSGANGQVICSLTPH-VPFKLVSTYKNYYSLVLDSALDRES 417
Query: 68 KIGPSNVYVNVRCDRRRTTDPSF--VIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXX 125
+ + V R PS VSV V DVNDNAP + Y V V E
Sbjct: 418 -VSAYELVVTARDGG----SPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGC 472
Query: 126 XXXXXXXSDRDQPGPHSALHYAVLP---GPH--SEYLGFENELEPIIVVKKPLDFETVNN 180
D D ++ + Y+++ G H S Y+ E + ++ PLD E +
Sbjct: 473 HIFTVSAWDADAQ-KNALVSYSLVERRVGEHALSSYVSVHAESGKVYALQ-PLDHEELEL 530
Query: 181 FTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYE-------HYTALLPDDAEEGTF 233
++ +D G PPL S+ TLQV VLD +D P + L+P G
Sbjct: 531 LQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHV 590
Query: 234 LTTSPGPISAADQDLGINAPLQY----SSTGDHKQLIVVNKDTGQVAATKQL 281
+ + A D D G NA L Y ++ G H V TG+++ T+ L
Sbjct: 591 V----AKVRAVDADSGYNAWLSYELQPAAVGAHIP-FHVGLYTGEISTTRIL 637
>AF152308-1|AAD43702.1| 941|Homo sapiens protocadherin alpha 12
protein.
Length = 941
Score = 95.5 bits (227), Expect = 7e-19
Identities = 115/476 (24%), Positives = 190/476 (39%), Gaps = 33/476 (6%)
Query: 63 LDREEKIGPS---NVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSE 119
+DRE+ G S ++++ V DR P V V V V D+NDN P + V VSE
Sbjct: 90 IDREKLCGRSAECSIHLEVIVDR-----PLQVFHVDVEVKDINDNPPVFREREQKVPVSE 144
Query: 120 TXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEY---LGFENELEPIIVVKKPLDFE 176
+ SD D G +S L YA+ + E + + P +V++K LD E
Sbjct: 145 SAPLDSHFPLEGASDADI-GVNSLLTYALSLNENFELKIKTKKDKSILPELVLRKLLDRE 203
Query: 177 TVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTT 236
+ L V D G P L +Q+TVLD +D P F Y +L ++ + T +
Sbjct: 204 QTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPAFDKPSYKVVLSENVQNDTRVIQ 263
Query: 237 SPGPISAADQDLGINAPLQYSSTG----DHKQLIVVNKDTGQVAATKQLIAELDPSVTIV 292
++A+D D G+N + Y K + +N DTG++ +L E + + I
Sbjct: 264 ----LNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGEIRIYGELDFEENNAYEIQ 319
Query: 293 LKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTT 352
+ A P ++A + T S V E A G+V+ ++
Sbjct: 320 VNAIDKGIP---SMAGHSMVLVEVLDVNDNVPEVMVTS--LSLPVQEDAQVGTVIALISV 374
Query: 353 VPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSISND 412
+++ + F N ++L +LD E+ S Y V D S
Sbjct: 375 SDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTARDGGSPS 434
Query: 413 ---TASINISVEDVNEWEPRFRHPQYE-FEXXXXXXXXXXXXXXXXXXXXVAHDGDAGTL 468
TA +++ V DVN+ P F P+Y F + + +L
Sbjct: 435 LWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQKNALVSYSL 494
Query: 469 ALSLAGQHARMFYINASGDLFLREEAIGNLNSSSLHLV---ATAIDSGIPPRQTSV 521
G+HA Y++ + + A+ L+ L L+ +A D+G+PP ++V
Sbjct: 495 VERRVGEHALSSYVSVHAESG-KVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549
Score = 65.7 bits (153), Expect = 7e-10
Identities = 83/292 (28%), Positives = 120/292 (41%), Gaps = 34/292 (11%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKN---LTLLRALDREE 67
+ ED +G++I +SV+ S G + L +V KN L L ALDRE
Sbjct: 359 VQEDAQVGTVIALISVSDRDSGANGQVICSLTPH-VPFKLVSTYKNYYSLVLDSALDRES 417
Query: 68 KIGPSNVYVNVRCDRRRTTDPSF--VIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXX 125
+ + V R PS VSV V DVNDNAP + Y V V E
Sbjct: 418 -VSAYELVVTARDGG----SPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGC 472
Query: 126 XXXXXXXSDRDQPGPHSALHYAVLP---GPH--SEYLGFENELEPIIVVKKPLDFETVNN 180
D D ++ + Y+++ G H S Y+ E + ++ PLD E +
Sbjct: 473 HIFTVSAWDADAQ-KNALVSYSLVERRVGEHALSSYVSVHAESGKVYALQ-PLDHEELEL 530
Query: 181 FTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYE-------HYTALLPDDAEEGTF 233
++ +D G PPL S+ TLQV VLD +D P + L+P G
Sbjct: 531 LQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHV 590
Query: 234 LTTSPGPISAADQDLGINAPLQY----SSTGDHKQLIVVNKDTGQVAATKQL 281
+ + A D D G NA L Y ++ G H V TG+++ T+ L
Sbjct: 591 V----AKVRAVDADSGYNAWLSYELQPAAVGAHIP-FHVGLYTGEISTTRIL 637
>AC005609-2|AAC34315.1| 792|Homo sapiens KIAA0345-like 2 protein.
Length = 792
Score = 95.5 bits (227), Expect = 7e-19
Identities = 115/476 (24%), Positives = 190/476 (39%), Gaps = 33/476 (6%)
Query: 63 LDREEKIGPS---NVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSE 119
+DRE+ G S ++++ V DR P V V V V D+NDN P + V VSE
Sbjct: 90 IDREKLCGRSAECSIHLEVIVDR-----PLQVFHVDVEVKDINDNPPVFREREQKVPVSE 144
Query: 120 TXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEY---LGFENELEPIIVVKKPLDFE 176
+ SD D G +S L YA+ + E + + P +V++K LD E
Sbjct: 145 SAPLDSHFPLEGASDADI-GVNSLLTYALSLNENFELKIKTKKDKSILPELVLRKLLDRE 203
Query: 177 TVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTT 236
+ L V D G P L +Q+TVLD +D P F Y +L ++ + T +
Sbjct: 204 QTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPAFDKPSYKVVLSENVQNDTRVIQ 263
Query: 237 SPGPISAADQDLGINAPLQYSSTG----DHKQLIVVNKDTGQVAATKQLIAELDPSVTIV 292
++A+D D G+N + Y K + +N DTG++ +L E + + I
Sbjct: 264 ----LNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGEIRIYGELDFEENNAYEIQ 319
Query: 293 LKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTT 352
+ A P ++A + T S V E A G+V+ ++
Sbjct: 320 VNAIDKGIP---SMAGHSMVLVEVLDVNDNVPEVMVTS--LSLPVQEDAQVGTVIALISV 374
Query: 353 VPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSISND 412
+++ + F N ++L +LD E+ S Y V D S
Sbjct: 375 SDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTARDGGSPS 434
Query: 413 ---TASINISVEDVNEWEPRFRHPQYE-FEXXXXXXXXXXXXXXXXXXXXVAHDGDAGTL 468
TA +++ V DVN+ P F P+Y F + + +L
Sbjct: 435 LWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQKNALVSYSL 494
Query: 469 ALSLAGQHARMFYINASGDLFLREEAIGNLNSSSLHLV---ATAIDSGIPPRQTSV 521
G+HA Y++ + + A+ L+ L L+ +A D+G+PP ++V
Sbjct: 495 VERRVGEHALSSYVSVHAESG-KVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549
Score = 65.7 bits (153), Expect = 7e-10
Identities = 83/292 (28%), Positives = 120/292 (41%), Gaps = 34/292 (11%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKN---LTLLRALDREE 67
+ ED +G++I +SV+ S G + L +V KN L L ALDRE
Sbjct: 359 VQEDAQVGTVIALISVSDRDSGANGQVICSLTPH-VPFKLVSTYKNYYSLVLDSALDRES 417
Query: 68 KIGPSNVYVNVRCDRRRTTDPSF--VIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXX 125
+ + V R PS VSV V DVNDNAP + Y V V E
Sbjct: 418 -VSAYELVVTARDGG----SPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGC 472
Query: 126 XXXXXXXSDRDQPGPHSALHYAVLP---GPH--SEYLGFENELEPIIVVKKPLDFETVNN 180
D D ++ + Y+++ G H S Y+ E + ++ PLD E +
Sbjct: 473 HIFTVSAWDADAQ-KNALVSYSLVERRVGEHALSSYVSVHAESGKVYALQ-PLDHEELEL 530
Query: 181 FTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYE-------HYTALLPDDAEEGTF 233
++ +D G PPL S+ TLQV VLD +D P + L+P G
Sbjct: 531 LQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHV 590
Query: 234 LTTSPGPISAADQDLGINAPLQY----SSTGDHKQLIVVNKDTGQVAATKQL 281
+ + A D D G NA L Y ++ G H V TG+++ T+ L
Sbjct: 591 V----AKVRAVDADSGYNAWLSYELQPAAVGAHIP-FHVGLYTGEISTTRIL 637
>AY358199-1|AAQ88566.1| 781|Homo sapiens CDH24 protein.
Length = 781
Score = 95.1 bits (226), Expect = 1e-18
Identities = 112/447 (25%), Positives = 183/447 (40%), Gaps = 29/447 (6%)
Query: 9 FFISEDT--PIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDRE 66
FF+ E+ P +IG L + D E L + G I + N+ + ++LDRE
Sbjct: 51 FFVIEEYAGPEPVLIGKLHSDVDRGEGRTKYLLTGEGAGTVFVIDEATGNIHVTKSLDRE 110
Query: 67 EKIGPSNVYVNV-RCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXX 125
EK + V R R PS I ++V D+NDN P + PY V E
Sbjct: 111 EKAQYVLLAQAVDRASNRPLEPPSEFI---IKVQDINDNPPIFPLGPYHATVPEMSNVGT 167
Query: 126 XXXXXXXSDRDQP--GPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTI 183
D D P G + L Y VL G + + + + +D ET F +
Sbjct: 168 SVIQVTAHDADDPSYGNSAKLVYTVLDG--LPFFSVDPQTGVVRTAIPNMDRETQEEFLV 225
Query: 184 KLRVQDQGS--PPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPI 241
++ +D G L TT+ VT+ D +D PKF Y + + A GT + G +
Sbjct: 226 VIQAKDMGGHMGGLSGSTTVTVTLSDVNDNPPKFPQSLYQFSVVETAGPGTLV----GRL 281
Query: 242 SAADQDLGINAPLQYS-STGDHKQLIVVNKD----TGQVAATKQLIAELDPSVTIVLKAT 296
A D DLG NA + YS G+ + ++ D G + K L E S + ++AT
Sbjct: 282 RAQDPDLGDNALMAYSILDGEGSEAFSISTDLQGRDGLLTVRKPLDFESQRSYSFRVEAT 341
Query: 297 Q-VDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQ 355
+ +P FTQ Y TV E +PG+++ ++
Sbjct: 342 NTLIDPAYLRRGPFKDVASVRVAVQDAPEPPAFTQAAYHLTVPENKAPGTLVGQISAA-- 399
Query: 356 NTEFRESPLQFYVSDRSFLDK-FAIN-NAGEVILRRSLDYETTSNYFYQVMVTDSISNDT 413
+ + SP+++ + S ++ F+I G + LD E + + V+ T+ S+
Sbjct: 400 DLDSPASPIRYSILPHSDPERCFSIQPEEGTIHTAAPLDREARAWHNLTVLATELDSSAQ 459
Query: 414 AS-INISVE--DVNEWEPRFRHPQYEF 437
AS + ++++ D N+ P+ P F
Sbjct: 460 ASRVQVAIQTLDENDNAPQLAEPYDTF 486
>AY260900-1|AAP20590.1| 781|Homo sapiens cadherin-24 protein.
Length = 781
Score = 95.1 bits (226), Expect = 1e-18
Identities = 112/447 (25%), Positives = 183/447 (40%), Gaps = 29/447 (6%)
Query: 9 FFISEDT--PIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDRE 66
FF+ E+ P +IG L + D E L + G I + N+ + ++LDRE
Sbjct: 51 FFVIEEYAGPEPVLIGKLHSDVDRGEGRTKYLLTGEGAGTVFVIDEATGNIHVTKSLDRE 110
Query: 67 EKIGPSNVYVNV-RCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXX 125
EK + V R R PS I ++V D+NDN P + PY V E
Sbjct: 111 EKAQYVLLAQAVDRASNRPLEPPSEFI---IKVQDINDNPPIFPLGPYHATVPEMSNVGT 167
Query: 126 XXXXXXXSDRDQP--GPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTI 183
D D P G + L Y VL G + + + + +D ET F +
Sbjct: 168 SVIQVTAHDADDPSYGNSAKLVYTVLDG--LPFFSVDPQTGVVRTAIPNMDRETQEEFLV 225
Query: 184 KLRVQDQGS--PPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPI 241
++ +D G L TT+ VT+ D +D PKF Y + + A GT + G +
Sbjct: 226 VIQAKDMGGHMGGLSGSTTVTVTLSDVNDNPPKFPQSLYQFSVVETAGPGTLV----GRL 281
Query: 242 SAADQDLGINAPLQYS-STGDHKQLIVVNKD----TGQVAATKQLIAELDPSVTIVLKAT 296
A D DLG NA + YS G+ + ++ D G + K L E S + ++AT
Sbjct: 282 RAQDPDLGDNALMAYSILDGEGSEAFSISTDLQGRDGLLTVRKPLDFESQRSYSFRVEAT 341
Query: 297 Q-VDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQ 355
+ +P FTQ Y TV E +PG+++ ++
Sbjct: 342 NTLIDPAYLRRGPFKDVASVRVAVQDAPEPPAFTQAAYHLTVPENKAPGTLVGQISAA-- 399
Query: 356 NTEFRESPLQFYVSDRSFLDK-FAIN-NAGEVILRRSLDYETTSNYFYQVMVTDSISNDT 413
+ + SP+++ + S ++ F+I G + LD E + + V+ T+ S+
Sbjct: 400 DLDSPASPIRYSILPHSDPERCFSIQPEEGTIHTAAPLDREARAWHNLTVLATELDSSAQ 459
Query: 414 AS-INISVE--DVNEWEPRFRHPQYEF 437
AS + ++++ D N+ P+ P F
Sbjct: 460 ASRVQVAIQTLDENDNAPQLAEPYDTF 486
>BC104950-1|AAI04951.1| 823|Homo sapiens protocadherin gamma
subfamily A, 2, isoform 2 precursor protein.
Length = 823
Score = 94.7 bits (225), Expect = 1e-18
Identities = 105/443 (23%), Positives = 184/443 (41%), Gaps = 34/443 (7%)
Query: 9 FFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAA--VGIVPGSKNLTLLRALDR 65
+ + E+ GS +G ++ + G L + +R+ +G + + P S +L +DR
Sbjct: 33 YSVREEIDRGSFVGNIAKDLGLEPLALAEQGVRIVSRGRSQLFALNPRSGSLVTANRIDR 92
Query: 66 EE---KIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXX 122
EE + P + N+ + + T + V V + D+NDNAP++ +++SET
Sbjct: 93 EELCAQSAPCLLNFNILLEDKLT-----IYSVEVEITDINDNAPRFGVEELELKISETTT 147
Query: 123 XXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEY---LGFENELEPIIVVKKPLDFETVN 179
D D G ++ YA+ P H G + P +V+++ LD E
Sbjct: 148 PGFRIPLKNAHDADV-GENALQKYALNPNDHFSLDVRRGADGNKYPELVLERSLDREEEA 206
Query: 180 NFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPG 239
+ L D G P L + + V VLDA+D P FT Y +P++ GT + T
Sbjct: 207 VHHLVLVASDGGDPVLSGTSRICVKVLDANDNAPVFTQPEYRISIPENTLVGTRILT--- 263
Query: 240 PISAADQDLGINAPLQY---SSTGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKAT 296
++A D D G A + Y S G+ ++ + +G++ K L E I ++A
Sbjct: 264 -VTATDADEGYYAQVVYFLEKSPGETSEVFELKSTSGELTIIKDLDYEDATFHEIDIEAQ 322
Query: 297 QVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQN 356
D P L +F +++VSE + PG+++ ++
Sbjct: 323 --DGP-----GLLTRAKVIVTVLDVNDNAPEFYMTSATSSVSEDSLPGTIIGLFNVHDRD 375
Query: 357 TEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTD----SISND 412
+ D F + +++N ++ R+LD E S Y + D S+S D
Sbjct: 376 SGQNAFTTCSLPEDLPFKLEKSVDNYYRLVTTRALDREQFSFYNITLTAKDGGNPSLSTD 435
Query: 413 TASINISVEDVNEWEPRFRHPQY 435
A I + V D+N+ P F Y
Sbjct: 436 -AHILLQVADINDNAPAFSRTSY 457
Score = 76.6 bits (180), Expect = 4e-13
Identities = 80/315 (25%), Positives = 125/315 (39%), Gaps = 26/315 (8%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEK--GAAVGIVPGSKNLTLLRALDREEK 68
+SED+ G+IIG +V+ S T L E V L RALDRE+
Sbjct: 356 VSEDSLPGTIIGLFNVHDRDSGQNAFTTCSLPEDLPFKLEKSVDNYYRLVTTRALDREQF 415
Query: 69 IGPSNVYVNVRCDRRRTTDPSFVIPVSV--RVWDVNDNAPQWEGAPYAVRVSETXXXXXX 126
+ N+ + +PS + +V D+NDNAP + Y+ + E
Sbjct: 416 S-----FYNITLTAKDGGNPSLSTDAHILLQVADINDNAPAFSRTSYSTYIPENNPRGAS 470
Query: 127 XXXXXXSDRDQ-PGPHSALHYA---VLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFT 182
D D H +A V P S Y+ ++ ++ + D+E + +
Sbjct: 471 VFSVTAHDPDSNDNAHVTYSFAEDTVQGAPLSSYISINSDTG-VLYALRSFDYEQLRDLQ 529
Query: 183 IKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHY-------TALLPDDAEEGTFLT 235
+ + +D G+PPL S+ +L + VLD +D P+ Y + L P AE G +T
Sbjct: 530 VWVIARDSGNPPLSSNVSLSLFVLDQNDNAPEILYPAFPTDGSTGVELAPRSAEPGYLVT 589
Query: 236 TSPGPISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLK 294
+ A D+D G NA L Y L V TG+V + L+ ++V+
Sbjct: 590 ----KVVAVDRDSGQNAWLSYHLLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVA 645
Query: 295 ATQVDNPDRYALATL 309
P A TL
Sbjct: 646 IQDHGQPPLSATVTL 660
Score = 61.7 bits (143), Expect = 1e-08
Identities = 59/214 (27%), Positives = 87/214 (40%), Gaps = 12/214 (5%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
V V V DVNDNAP++ VSE DRD +A LP
Sbjct: 333 VIVTVLDVNDNAPEFYMTSATSSVSEDSLPGTIIGLFNVHDRDSG--QNAFTTCSLPEDL 390
Query: 154 SEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNP 213
L + +V + LD E + + I L +D G+P L +D + + V D +D P
Sbjct: 391 PFKLEKSVDNYYRLVTTRALDREQFSFYNITLTAKDGGNPSLSTDAHILLQVADINDNAP 450
Query: 214 KFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQ------LIV 267
F+ Y+ +P++ G S ++A D D NA + YS D Q I
Sbjct: 451 AFSRTSYSTYIPENNPRG----ASVFSVTAHDPDSNDNAHVTYSFAEDTVQGAPLSSYIS 506
Query: 268 VNKDTGQVAATKQLIAELDPSVTIVLKATQVDNP 301
+N DTG + A + E + + + A NP
Sbjct: 507 INSDTGVLYALRSFDYEQLRDLQVWVIARDSGNP 540
Score = 37.1 bits (82), Expect = 0.28
Identities = 49/214 (22%), Positives = 85/214 (39%), Gaps = 19/214 (8%)
Query: 8 SFFISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQE---KGAA----VGIVPGSKNLTLL 60
S +I E+ P G+ + +++ + S D +T E +GA + I + L L
Sbjct: 458 STYIPENNPRGASVFSVTAHDPDSNDNAHVTYSFAEDTVQGAPLSSYISINSDTGVLYAL 517
Query: 61 RALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQ-------WEGAPY 113
R+ D E+ + V+V R + + +S+ V D NDNAP+ +G+
Sbjct: 518 RSFDYEQ-LRDLQVWVIARDSGNPPLSSN--VSLSLFVLDQNDNAPEILYPAFPTDGSTG 574
Query: 114 AVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPL 173
+ DRD G ++ L Y +L + + L
Sbjct: 575 VELAPRSAEPGYLVTKVVAVDRDS-GQNAWLSYHLLKASEPGLFSVGLHTGEVRTARALL 633
Query: 174 DFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLD 207
D + + ++ + +QD G PPL + TL V V D
Sbjct: 634 DRDALKQ-SLVVAIQDHGQPPLSATVTLTVAVAD 666
>BC093871-1|AAH93871.1| 823|Homo sapiens protocadherin gamma
subfamily A, 2, isoform 2 precursor protein.
Length = 823
Score = 94.7 bits (225), Expect = 1e-18
Identities = 105/443 (23%), Positives = 184/443 (41%), Gaps = 34/443 (7%)
Query: 9 FFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAA--VGIVPGSKNLTLLRALDR 65
+ + E+ GS +G ++ + G L + +R+ +G + + P S +L +DR
Sbjct: 33 YSVREEIDRGSFVGNIAKDLGLEPLALAEQGVRIVSRGRSQLFALNPRSGSLVTANRIDR 92
Query: 66 EE---KIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXX 122
EE + P + N+ + + T + V V + D+NDNAP++ +++SET
Sbjct: 93 EELCAQSAPCLLNFNILLEDKLT-----IYSVEVEITDINDNAPRFGVEELELKISETTT 147
Query: 123 XXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEY---LGFENELEPIIVVKKPLDFETVN 179
D D G ++ YA+ P H G + P +V+++ LD E
Sbjct: 148 PGFRIPLKNAHDADV-GENALQKYALNPNDHFSLDVRRGADGNKYPELVLERSLDREEEA 206
Query: 180 NFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPG 239
+ L D G P L + + V VLDA+D P FT Y +P++ GT + T
Sbjct: 207 VHHLVLVASDGGDPVLSGTSRICVKVLDANDNAPVFTQPEYRISIPENTLVGTRILT--- 263
Query: 240 PISAADQDLGINAPLQY---SSTGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKAT 296
++A D D G A + Y S G+ ++ + +G++ K L E I ++A
Sbjct: 264 -VTATDADEGYYAQVVYFLEKSPGETSEVFELKSTSGELTIIKDLDYEDATFHEIDIEAQ 322
Query: 297 QVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQN 356
D P L +F +++VSE + PG+++ ++
Sbjct: 323 --DGP-----GLLTRAKVIVTVLDVNDNAPEFYMTSATSSVSEDSLPGTIIGLFNVHDRD 375
Query: 357 TEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTD----SISND 412
+ D F + +++N ++ R+LD E S Y + D S+S D
Sbjct: 376 SGQNAFTTCSLPEDLPFKLEKSVDNYYRLVTTRALDREQFSFYNITLTAKDGGNPSLSTD 435
Query: 413 TASINISVEDVNEWEPRFRHPQY 435
A I + V D+N+ P F Y
Sbjct: 436 -AHILLQVADINDNAPAFSRTSY 457
Score = 76.6 bits (180), Expect = 4e-13
Identities = 80/315 (25%), Positives = 125/315 (39%), Gaps = 26/315 (8%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEK--GAAVGIVPGSKNLTLLRALDREEK 68
+SED+ G+IIG +V+ S T L E V L RALDRE+
Sbjct: 356 VSEDSLPGTIIGLFNVHDRDSGQNAFTTCSLPEDLPFKLEKSVDNYYRLVTTRALDREQF 415
Query: 69 IGPSNVYVNVRCDRRRTTDPSFVIPVSV--RVWDVNDNAPQWEGAPYAVRVSETXXXXXX 126
+ N+ + +PS + +V D+NDNAP + Y+ + E
Sbjct: 416 S-----FYNITLTAKDGGNPSLSTDAHILLQVADINDNAPAFSRTSYSTYIPENNPRGAS 470
Query: 127 XXXXXXSDRDQ-PGPHSALHYA---VLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFT 182
D D H +A V P S Y+ ++ ++ + D+E + +
Sbjct: 471 VFSVTAHDPDSNDNAHVTYSFAEDTVQGAPLSSYISINSDTG-VLYALRSFDYEQLRDLQ 529
Query: 183 IKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHY-------TALLPDDAEEGTFLT 235
+ + +D G+PPL S+ +L + VLD +D P+ Y + L P AE G +T
Sbjct: 530 VWVIARDSGNPPLSSNVSLSLFVLDQNDNAPEILYPAFPTDGSTGVELAPRSAEPGYLVT 589
Query: 236 TSPGPISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLK 294
+ A D+D G NA L Y L V TG+V + L+ ++V+
Sbjct: 590 ----KVVAVDRDSGQNAWLSYHLLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVA 645
Query: 295 ATQVDNPDRYALATL 309
P A TL
Sbjct: 646 IQDHGQPPLSATVTL 660
Score = 61.7 bits (143), Expect = 1e-08
Identities = 59/214 (27%), Positives = 87/214 (40%), Gaps = 12/214 (5%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
V V V DVNDNAP++ VSE DRD +A LP
Sbjct: 333 VIVTVLDVNDNAPEFYMTSATSSVSEDSLPGTIIGLFNVHDRDSG--QNAFTTCSLPEDL 390
Query: 154 SEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNP 213
L + +V + LD E + + I L +D G+P L +D + + V D +D P
Sbjct: 391 PFKLEKSVDNYYRLVTTRALDREQFSFYNITLTAKDGGNPSLSTDAHILLQVADINDNAP 450
Query: 214 KFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQ------LIV 267
F+ Y+ +P++ G S ++A D D NA + YS D Q I
Sbjct: 451 AFSRTSYSTYIPENNPRG----ASVFSVTAHDPDSNDNAHVTYSFAEDTVQGAPLSSYIS 506
Query: 268 VNKDTGQVAATKQLIAELDPSVTIVLKATQVDNP 301
+N DTG + A + E + + + A NP
Sbjct: 507 INSDTGVLYALRSFDYEQLRDLQVWVIARDSGNP 540
Score = 37.1 bits (82), Expect = 0.28
Identities = 49/214 (22%), Positives = 85/214 (39%), Gaps = 19/214 (8%)
Query: 8 SFFISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQE---KGAA----VGIVPGSKNLTLL 60
S +I E+ P G+ + +++ + S D +T E +GA + I + L L
Sbjct: 458 STYIPENNPRGASVFSVTAHDPDSNDNAHVTYSFAEDTVQGAPLSSYISINSDTGVLYAL 517
Query: 61 RALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQ-------WEGAPY 113
R+ D E+ + V+V R + + +S+ V D NDNAP+ +G+
Sbjct: 518 RSFDYEQ-LRDLQVWVIARDSGNPPLSSN--VSLSLFVLDQNDNAPEILYPAFPTDGSTG 574
Query: 114 AVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPL 173
+ DRD G ++ L Y +L + + L
Sbjct: 575 VELAPRSAEPGYLVTKVVAVDRDS-GQNAWLSYHLLKASEPGLFSVGLHTGEVRTARALL 633
Query: 174 DFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLD 207
D + + ++ + +QD G PPL + TL V V D
Sbjct: 634 DRDALKQ-SLVVAIQDHGQPPLSATVTLTVAVAD 666
>AF152508-1|AAD43769.1| 823|Homo sapiens protocadherin gamma A2
short form protein protein.
Length = 823
Score = 94.7 bits (225), Expect = 1e-18
Identities = 105/443 (23%), Positives = 184/443 (41%), Gaps = 34/443 (7%)
Query: 9 FFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAA--VGIVPGSKNLTLLRALDR 65
+ + E+ GS +G ++ + G L + +R+ +G + + P S +L +DR
Sbjct: 33 YSVREEIDRGSFVGNIAKDLGLEPLALAEQGVRIVSRGRSQLFALNPRSGSLVTANRIDR 92
Query: 66 EE---KIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXX 122
EE + P + N+ + + T + V V + D+NDNAP++ +++SET
Sbjct: 93 EELCAQSAPCLLNFNILLEDKLT-----IYSVEVEITDINDNAPRFGVEELELKISETTT 147
Query: 123 XXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEY---LGFENELEPIIVVKKPLDFETVN 179
D D G ++ YA+ P H G + P +V+++ LD E
Sbjct: 148 PGFRIPLKNAHDADV-GENALQKYALNPNDHFSLDVRRGADGNKYPELVLERSLDREEEA 206
Query: 180 NFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPG 239
+ L D G P L + + V VLDA+D P FT Y +P++ GT + T
Sbjct: 207 VHHLVLVASDGGDPVLSGTSRICVKVLDANDNAPVFTQPEYRISIPENTLVGTRILT--- 263
Query: 240 PISAADQDLGINAPLQY---SSTGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKAT 296
++A D D G A + Y S G+ ++ + +G++ K L E I ++A
Sbjct: 264 -VTATDADEGYYAQVVYFLEKSPGETSEVFELKSTSGELTIIKDLDYEDATFHEIDIEAQ 322
Query: 297 QVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQN 356
D P L +F +++VSE + PG+++ ++
Sbjct: 323 --DGP-----GLLTRAKVIVTVLDVNDNAPEFYMTSATSSVSEDSLPGTIIGLFNVHDRD 375
Query: 357 TEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTD----SISND 412
+ D F + +++N ++ R+LD E S Y + D S+S D
Sbjct: 376 SGQNAFTTCSLPEDLPFKLEKSVDNYYRLVTTRALDREQFSFYNITLTAKDGGNPSLSTD 435
Query: 413 TASINISVEDVNEWEPRFRHPQY 435
A I + V D+N+ P F Y
Sbjct: 436 -AHILLQVADINDNAPAFSRTSY 457
Score = 76.6 bits (180), Expect = 4e-13
Identities = 80/315 (25%), Positives = 125/315 (39%), Gaps = 26/315 (8%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEK--GAAVGIVPGSKNLTLLRALDREEK 68
+SED+ G+IIG +V+ S T L E V L RALDRE+
Sbjct: 356 VSEDSLPGTIIGLFNVHDRDSGQNAFTTCSLPEDLPFKLEKSVDNYYRLVTTRALDREQF 415
Query: 69 IGPSNVYVNVRCDRRRTTDPSFVIPVSV--RVWDVNDNAPQWEGAPYAVRVSETXXXXXX 126
+ N+ + +PS + +V D+NDNAP + Y+ + E
Sbjct: 416 S-----FYNITLTAKDGGNPSLSTDAHILLQVADINDNAPAFSRTSYSTYIPENNPRGAS 470
Query: 127 XXXXXXSDRDQ-PGPHSALHYA---VLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFT 182
D D H +A V P S Y+ ++ ++ + D+E + +
Sbjct: 471 VFSVTAHDPDSNDNAHVTYSFAEDTVQGAPLSSYISINSDTG-VLYALRSFDYEQLRDLQ 529
Query: 183 IKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHY-------TALLPDDAEEGTFLT 235
+ + +D G+PPL S+ +L + VLD +D P+ Y + L P AE G +T
Sbjct: 530 VWVIARDSGNPPLSSNVSLSLFVLDQNDNAPEILYPAFPTDGSTGVELAPRSAEPGYLVT 589
Query: 236 TSPGPISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLK 294
+ A D+D G NA L Y L V TG+V + L+ ++V+
Sbjct: 590 ----KVVAVDRDSGQNAWLSYHLLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVA 645
Query: 295 ATQVDNPDRYALATL 309
P A TL
Sbjct: 646 IQDHGQPPLSATVTL 660
Score = 61.7 bits (143), Expect = 1e-08
Identities = 59/214 (27%), Positives = 87/214 (40%), Gaps = 12/214 (5%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
V V V DVNDNAP++ VSE DRD +A LP
Sbjct: 333 VIVTVLDVNDNAPEFYMTSATSSVSEDSLPGTIIGLFNVHDRDSG--QNAFTTCSLPEDL 390
Query: 154 SEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNP 213
L + +V + LD E + + I L +D G+P L +D + + V D +D P
Sbjct: 391 PFKLEKSVDNYYRLVTTRALDREQFSFYNITLTAKDGGNPSLSTDAHILLQVADINDNAP 450
Query: 214 KFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQ------LIV 267
F+ Y+ +P++ G S ++A D D NA + YS D Q I
Sbjct: 451 AFSRTSYSTYIPENNPRG----ASVFSVTAHDPDSNDNAHVTYSFAEDTVQGAPLSSYIS 506
Query: 268 VNKDTGQVAATKQLIAELDPSVTIVLKATQVDNP 301
+N DTG + A + E + + + A NP
Sbjct: 507 INSDTGVLYALRSFDYEQLRDLQVWVIARDSGNP 540
Score = 37.1 bits (82), Expect = 0.28
Identities = 49/214 (22%), Positives = 85/214 (39%), Gaps = 19/214 (8%)
Query: 8 SFFISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQE---KGAA----VGIVPGSKNLTLL 60
S +I E+ P G+ + +++ + S D +T E +GA + I + L L
Sbjct: 458 STYIPENNPRGASVFSVTAHDPDSNDNAHVTYSFAEDTVQGAPLSSYISINSDTGVLYAL 517
Query: 61 RALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQ-------WEGAPY 113
R+ D E+ + V+V R + + +S+ V D NDNAP+ +G+
Sbjct: 518 RSFDYEQ-LRDLQVWVIARDSGNPPLSSN--VSLSLFVLDQNDNAPEILYPAFPTDGSTG 574
Query: 114 AVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPL 173
+ DRD G ++ L Y +L + + L
Sbjct: 575 VELAPRSAEPGYLVTKVVAVDRDS-GQNAWLSYHLLKASEPGLFSVGLHTGEVRTARALL 633
Query: 174 DFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLD 207
D + + ++ + +QD G PPL + TL V V D
Sbjct: 634 DRDALKQ-SLVVAIQDHGQPPLSATVTLTVAVAD 666
>AF152322-1|AAD43716.1| 932|Homo sapiens protocadherin gamma A2
protein.
Length = 932
Score = 94.7 bits (225), Expect = 1e-18
Identities = 105/443 (23%), Positives = 184/443 (41%), Gaps = 34/443 (7%)
Query: 9 FFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAA--VGIVPGSKNLTLLRALDR 65
+ + E+ GS +G ++ + G L + +R+ +G + + P S +L +DR
Sbjct: 33 YSVREEIDRGSFVGNIAKDLGLEPLALAEQGVRIVSRGRSQLFALNPRSGSLVTANRIDR 92
Query: 66 EE---KIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXX 122
EE + P + N+ + + T + V V + D+NDNAP++ +++SET
Sbjct: 93 EELCAQSAPCLLNFNILLEDKLT-----IYSVEVEITDINDNAPRFGVEELELKISETTT 147
Query: 123 XXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEY---LGFENELEPIIVVKKPLDFETVN 179
D D G ++ YA+ P H G + P +V+++ LD E
Sbjct: 148 PGFRIPLKNAHDADV-GENALQKYALNPNDHFSLDVRRGADGNKYPELVLERSLDREEEA 206
Query: 180 NFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPG 239
+ L D G P L + + V VLDA+D P FT Y +P++ GT + T
Sbjct: 207 VHHLVLVASDGGDPVLSGTSRICVKVLDANDNAPVFTQPEYRISIPENTLVGTRILT--- 263
Query: 240 PISAADQDLGINAPLQY---SSTGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKAT 296
++A D D G A + Y S G+ ++ + +G++ K L E I ++A
Sbjct: 264 -VTATDADEGYYAQVVYFLEKSPGETSEVFELKSTSGELTIIKDLDYEDATFHEIDIEAQ 322
Query: 297 QVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQN 356
D P L +F +++VSE + PG+++ ++
Sbjct: 323 --DGP-----GLLTRAKVIVTVLDVNDNAPEFYMTSATSSVSEDSLPGTIIGLFNVHDRD 375
Query: 357 TEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTD----SISND 412
+ D F + +++N ++ R+LD E S Y + D S+S D
Sbjct: 376 SGQNAFTTCSLPEDLPFKLEKSVDNYYRLVTTRALDREQFSFYNITLTAKDGGNPSLSTD 435
Query: 413 TASINISVEDVNEWEPRFRHPQY 435
A I + V D+N+ P F Y
Sbjct: 436 -AHILLQVADINDNAPAFSRTSY 457
Score = 76.6 bits (180), Expect = 4e-13
Identities = 80/315 (25%), Positives = 125/315 (39%), Gaps = 26/315 (8%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEK--GAAVGIVPGSKNLTLLRALDREEK 68
+SED+ G+IIG +V+ S T L E V L RALDRE+
Sbjct: 356 VSEDSLPGTIIGLFNVHDRDSGQNAFTTCSLPEDLPFKLEKSVDNYYRLVTTRALDREQF 415
Query: 69 IGPSNVYVNVRCDRRRTTDPSFVIPVSV--RVWDVNDNAPQWEGAPYAVRVSETXXXXXX 126
+ N+ + +PS + +V D+NDNAP + Y+ + E
Sbjct: 416 S-----FYNITLTAKDGGNPSLSTDAHILLQVADINDNAPAFSRTSYSTYIPENNPRGAS 470
Query: 127 XXXXXXSDRDQ-PGPHSALHYA---VLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFT 182
D D H +A V P S Y+ ++ ++ + D+E + +
Sbjct: 471 VFSVTAHDPDSNDNAHVTYSFAEDTVQGAPLSSYISINSDTG-VLYALRSFDYEQLRDLQ 529
Query: 183 IKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHY-------TALLPDDAEEGTFLT 235
+ + +D G+PPL S+ +L + VLD +D P+ Y + L P AE G +T
Sbjct: 530 VWVIARDSGNPPLSSNVSLSLFVLDQNDNAPEILYPAFPTDGSTGVELAPRSAEPGYLVT 589
Query: 236 TSPGPISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLK 294
+ A D+D G NA L Y L V TG+V + L+ ++V+
Sbjct: 590 ----KVVAVDRDSGQNAWLSYHLLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVA 645
Query: 295 ATQVDNPDRYALATL 309
P A TL
Sbjct: 646 IQDHGQPPLSATVTL 660
Score = 61.7 bits (143), Expect = 1e-08
Identities = 59/214 (27%), Positives = 87/214 (40%), Gaps = 12/214 (5%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
V V V DVNDNAP++ VSE DRD +A LP
Sbjct: 333 VIVTVLDVNDNAPEFYMTSATSSVSEDSLPGTIIGLFNVHDRDSG--QNAFTTCSLPEDL 390
Query: 154 SEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNP 213
L + +V + LD E + + I L +D G+P L +D + + V D +D P
Sbjct: 391 PFKLEKSVDNYYRLVTTRALDREQFSFYNITLTAKDGGNPSLSTDAHILLQVADINDNAP 450
Query: 214 KFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQ------LIV 267
F+ Y+ +P++ G S ++A D D NA + YS D Q I
Sbjct: 451 AFSRTSYSTYIPENNPRG----ASVFSVTAHDPDSNDNAHVTYSFAEDTVQGAPLSSYIS 506
Query: 268 VNKDTGQVAATKQLIAELDPSVTIVLKATQVDNP 301
+N DTG + A + E + + + A NP
Sbjct: 507 INSDTGVLYALRSFDYEQLRDLQVWVIARDSGNP 540
Score = 37.1 bits (82), Expect = 0.28
Identities = 49/214 (22%), Positives = 85/214 (39%), Gaps = 19/214 (8%)
Query: 8 SFFISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQE---KGAA----VGIVPGSKNLTLL 60
S +I E+ P G+ + +++ + S D +T E +GA + I + L L
Sbjct: 458 STYIPENNPRGASVFSVTAHDPDSNDNAHVTYSFAEDTVQGAPLSSYISINSDTGVLYAL 517
Query: 61 RALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQ-------WEGAPY 113
R+ D E+ + V+V R + + +S+ V D NDNAP+ +G+
Sbjct: 518 RSFDYEQ-LRDLQVWVIARDSGNPPLSSN--VSLSLFVLDQNDNAPEILYPAFPTDGSTG 574
Query: 114 AVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPL 173
+ DRD G ++ L Y +L + + L
Sbjct: 575 VELAPRSAEPGYLVTKVVAVDRDS-GQNAWLSYHLLKASEPGLFSVGLHTGEVRTARALL 633
Query: 174 DFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLD 207
D + + ++ + +QD G PPL + TL V V D
Sbjct: 634 DRDALKQ-SLVVAIQDHGQPPLSATVTLTVAVAD 666
>BC036674-1|AAH36674.1| 950|Homo sapiens PCDHA6 protein protein.
Length = 950
Score = 94.3 bits (224), Expect = 2e-18
Identities = 95/390 (24%), Positives = 166/390 (42%), Gaps = 26/390 (6%)
Query: 57 LTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVR 116
L L ++LDREE P++ D + + + + + V V DVNDNAP +E + Y VR
Sbjct: 194 LLLKKSLDREE--APAHNLFLTATDGGKP-ELTGTVQLLVTVLDVNDNAPTFEQSEYEVR 250
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYA---VLPGPHSEYLGFENELEPIIVVKKPL 173
+ E SDRD+ G + A+ Y+ ++ ++ + I V++ L
Sbjct: 251 IFENADNGTTVIRLNASDRDE-GANGAISYSFNSLVAAMVIDHFSIDRNTGEI-VIRGNL 308
Query: 174 DFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTF 233
DFE N + I + D+G PP+ T+ V +LD +D P+ + + +DA+ GT
Sbjct: 309 DFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTV 368
Query: 234 LTTSPGPISAADQDLGINAPLQYSSTGDHK-QLIVVNKDTGQVAATKQLIAELDPSVTIV 292
+ IS D D G N + S T +L+ K+ + L E + +V
Sbjct: 369 IAL----ISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELV 424
Query: 293 LKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTT 352
+ A +P +A A+L F Q +Y+ V E PG + T++
Sbjct: 425 VTARDGGSPSLWATASLSVEVADMNDNAPA-----FAQPEYTVFVKENNPPGCHIFTVSA 479
Query: 353 ----VPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTD 407
+N S ++ V +R+ +++ +G+V + LD+E +QV D
Sbjct: 480 RDADAQENALVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARD 539
Query: 408 S---ISNDTASINISVEDVNEWEPRFRHPQ 434
+ ++ + V D N+ P P+
Sbjct: 540 AGVPPLGSNVTLQVFVLDENDNAPALLAPR 569
Score = 90.6 bits (215), Expect = 2e-17
Identities = 98/389 (25%), Positives = 158/389 (40%), Gaps = 34/389 (8%)
Query: 63 LDREEKIGPS---NVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSE 119
+DREE G S ++++ V DR P V V V V D+NDN P + V + E
Sbjct: 90 IDREELCGRSAECSIHLEVIVDR-----PLQVFHVDVEVRDINDNPPLFPVEEQRVLIYE 144
Query: 120 TXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPI------IVVKKPL 173
+ SD D G +S L Y + SEY G + ++ +++KK L
Sbjct: 145 SRLPDSVFPLEGASDAD-VGSNSILTYKL---SSSEYFGLDVKINSDDNKQIGLLLKKSL 200
Query: 174 DFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTF 233
D E + L D G P L L VTVLD +D P F Y + ++A+ GT
Sbjct: 201 DREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEVRIFENADNGTT 260
Query: 234 LTTSPGPISAADQDLGINAPLQYSSTGDHKQLIV----VNKDTGQVAATKQLIAELDPSV 289
+ ++A+D+D G N + YS +++ ++++TG++ L E +
Sbjct: 261 VIR----LNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNLDFEQENLY 316
Query: 290 TIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLT 349
I++ AT +P T+ + S V E A G+V+
Sbjct: 317 KILIDATDKGHPPMAGHCTVLVRILDKNDNVP-----EIALTSLSLPVREDAQFGTVIAL 371
Query: 350 LTTVPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSI 409
++ ++ F N ++L +LD E+ S Y V D
Sbjct: 372 ISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGG 431
Query: 410 SND---TASINISVEDVNEWEPRFRHPQY 435
S TAS+++ V D+N+ P F P+Y
Sbjct: 432 SPSLWATASLSVEVADMNDNAPAFAQPEY 460
Score = 64.1 bits (149), Expect = 2e-09
Identities = 85/318 (26%), Positives = 121/318 (38%), Gaps = 30/318 (9%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKN---LTLLRALDREE 67
+ ED G++I +SVN S G + L +V KN L L ALDR E
Sbjct: 359 VREDAQFGTVIALISVNDLDSGANGQVNCSLTPH-VPFKLVSTFKNYYSLVLDSALDR-E 416
Query: 68 KIGPSNVYVNVRCDRRRTTDPSF--VIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXX 125
+ + V R PS +SV V D+NDNAP + Y V V E
Sbjct: 417 SVSAYELVVTA----RDGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGC 472
Query: 126 XXXXXXXSDRDQPG----PHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNF 181
D D +S + V S Y+ E + + +PLD E +
Sbjct: 473 HIFTVSARDADAQENALVSYSLVERRVGERALSSYISVHAESGKVYAL-QPLDHEELELL 531
Query: 182 TIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKF-------TYEHYTALLPDDAEEGTFL 234
++ +D G PPL S+ TLQV VLD +D P T + L+P G +
Sbjct: 532 QFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVV 591
Query: 235 TTSPGPISAADQDLGINAPLQYS---STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTI 291
+ A D D G NA L Y + V TG+++ T+ L P +
Sbjct: 592 ----AKVRAVDADSGYNAWLSYELQPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRL 647
Query: 292 VLKATQVDNPDRYALATL 309
++ P A AT+
Sbjct: 648 LVLVKDHGEPALTATATV 665
>AF217752-1|AAK51619.1| 794|Homo sapiens protocadherin-beta6
protein.
Length = 794
Score = 94.3 bits (224), Expect = 2e-18
Identities = 105/438 (23%), Positives = 177/438 (40%), Gaps = 26/438 (5%)
Query: 9 FFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAAVGIV--PGSKNLTLLRALDR 65
+ + E+T G+ + L+ + G +L R+ KG + P + +L L LDR
Sbjct: 32 YSVLEETESGTFVANLTKDLGLRVGELASRGARVVFKGNRQHLQFDPQTHDLLLNEKLDR 91
Query: 66 EEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXX 125
EE G + V + +P S+RV D+ND+AP++ +++SE
Sbjct: 92 EELCGSTEPCVLPF--QVLLENPLQFFQASLRVRDINDHAPEFPAREMLLKISEITMPGK 149
Query: 126 XXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLG---FENELEPIIVVKKPLDFETVNNFT 182
D D G + Y + PH L E P +V+ KPLD E
Sbjct: 150 IFPLKMAHDLDT-GSNGLQRYTISSNPHFHVLTRNRSEGRKFPELVLDKPLDREEQPQLR 208
Query: 183 IKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPIS 242
+ L D GSPP + +Q+ VLD +D P+F E Y A +P++ G+ + T +S
Sbjct: 209 LTLIALDGGSPPRSGTSEIQIQVLDINDNVPEFAQELYEAQVPENNPLGSLVIT----VS 264
Query: 243 AADQDLGINAPLQYS--STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDN 300
A D D G + Y+ D Q +N TG++ K L E S + ++AT D
Sbjct: 265 ARDLDAGSFGKVSYALFQVDDVNQPFEINAITGEIRLRKALDFEEIQSYDVDVEAT--DG 322
Query: 301 PDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFR 360
+L + T + + + E P + + ++
Sbjct: 323 GGLSGKCSLVVRVLDVNDNAP-----ELTMSFFISLIPENL-PEITVAVFSVSDADSGHN 376
Query: 361 ESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSIS---NDTASIN 417
+ + ++ FL + ++ N ++ +LD E+ + Y + VTD + SI
Sbjct: 377 QQVICSIENNLPFLLRPSVENFYTLVTEGALDRESRAEYNITITVTDLGTPRLKTQQSIT 436
Query: 418 ISVEDVNEWEPRFRHPQY 435
+ V DVN+ P F Y
Sbjct: 437 VQVSDVNDNVPAFTQTSY 454
Score = 74.9 bits (176), Expect = 1e-12
Identities = 68/229 (29%), Positives = 106/229 (46%), Gaps = 20/229 (8%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLP--G 151
++V+V DVNDN P + Y + V E +DRD G ++ + Y++LP
Sbjct: 435 ITVQVSDVNDNVPAFTQTSYTLFVRENNSPALHIGSVSATDRDS-GINAQVTYSLLPPQD 493
Query: 152 PH---SEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDA 208
PH S + + + ++ LD+E + +F ++ D+GSP L S+ +++ VLDA
Sbjct: 494 PHLPLSSLVSINADNGHLFALRS-LDYEALQSFEFRVGATDRGSPALSSEALVRLLVLDA 552
Query: 209 DDQNPKFTY------EHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYS-STGD 261
+D +P Y T L+P AE G +T + A D D G NA L Y
Sbjct: 553 NDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVT----KVVAVDGDSGQNAWLSYQLLKAT 608
Query: 262 HKQLIVVNKDTGQVAATKQLIAELDPSV-TIVLKATQVDNPDRYALATL 309
L V G+V T +L++E D + +V+ P R A ATL
Sbjct: 609 ELGLFGVWAHNGEV-RTARLLSERDAAKHRLVVLVKDNGEPPRSATATL 656
Score = 66.9 bits (156), Expect = 3e-10
Identities = 99/409 (24%), Positives = 157/409 (38%), Gaps = 24/409 (5%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRL---QEKGAAVGIVPGSKNLTLLRALDREE 67
+ E+ P+GS++ T+S + G ++ L + I + + L +ALD EE
Sbjct: 250 VPENNPLGSLVITVSARDLDAGSFGKVSYALFQVDDVNQPFEINAITGEIRLRKALDFEE 309
Query: 68 KIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXX 127
I +V V + S V VRV DVNDNAP+ + + + E
Sbjct: 310 -IQSYDVDVEATDGGGLSGKCSLV----VRVLDVNDNAPELTMSFFISLIPENLPEITVA 364
Query: 128 XXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRV 187
SD D + P EN +V + LD E+ + I + V
Sbjct: 365 VFSV-SDADSGHNQQVICSIENNLPFLLRPSVENFYT--LVTEGALDRESRAEYNITITV 421
Query: 188 QDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQD 247
D G+P L + ++ V V D +D P FT YT + ++ + G +SA D+D
Sbjct: 422 TDLGTPRLKTQQSITVQVSDVNDNVPAFTQTSYTLFVRENNSPALHI----GSVSATDRD 477
Query: 248 LGINAPLQYS---STGDH---KQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNP 301
GINA + YS H L+ +N D G + A + L E S + AT +P
Sbjct: 478 SGINAQVTYSLLPPQDPHLPLSSLVSINADNGHLFALRSLDYEALQSFEFRVGATDRGSP 537
Query: 302 DRYALATLXXXXXXXXXXX-XXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFR 360
+ A + LQ + V A PG L+T +
Sbjct: 538 ALSSEALVRLLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPG-YLVTKVVAVDGDSGQ 596
Query: 361 ESPLQFYVSDRSFLDKFAI-NNAGEVILRRSLDYETTSNYFYQVMVTDS 408
+ L + + + L F + + GEV R L + + V+V D+
Sbjct: 597 NAWLSYQLLKATELGLFGVWAHNGEVRTARLLSERDAAKHRLVVLVKDN 645
>AF152519-1|AAD43779.1| 814|Homo sapiens protocadherin gamma B3
short form protein protein.
Length = 814
Score = 94.3 bits (224), Expect = 2e-18
Identities = 105/437 (24%), Positives = 175/437 (40%), Gaps = 24/437 (5%)
Query: 9 FFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREE 67
+ I E+ GS++G L+ + G DL LR+ + + P + NL + +DREE
Sbjct: 35 YAIPEELDRGSLVGNLAKDLGFGVGDLPTRNLRVIAEKKFFTVSPENGNLLVSDRIDREE 94
Query: 68 KIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXX 127
G + V + + +F V+V + D+NDN P + + +SE
Sbjct: 95 ICGKKSTCV-LEFEMVAEKPLNF-FHVTVLIQDINDNPPTFSQNITELEISELALTGATF 152
Query: 128 XXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFEN---ELEPIIVVKKPLDFETVNNFTIK 184
D D G +S Y + P PH + EN P +V+K PLD E + +
Sbjct: 153 ALESAQDPDV-GVNSLQQYYLSPDPHFSLIQKENLDGSRYPELVLKAPLDREEQPHHHLV 211
Query: 185 LRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAA 244
L D G P T ++V V DA+D P FT + Y + ++ G +S + A
Sbjct: 212 LTAVDGGEPSRSCTTQIRVIVADANDNPPVFTQDMYRVNVAENLPAG----SSVLKVMAI 267
Query: 245 DQDLGINAPLQYSSTG---DHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNP 301
D D GINA + Y+ + +QL ++ TG++ +L E S TI ++A +
Sbjct: 268 DMDEGINAEIIYAFINIGKEVRQLFKLDSKTGELTTIGELDFEERDSYTIGVEAKDGGHH 327
Query: 302 DRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRE 361
Y + + T S + E A G+ + + T ++ F
Sbjct: 328 TAYCKVQIDISDENDNAP-------EITLASESQHIQEDAELGTAVALIKTHDLDSGFNG 380
Query: 362 SPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSIS---NDTASINI 418
L + F N ++ +LD E Y + TD + + + +I +
Sbjct: 381 EILCQLKGNFPFKIVQDTKNTYRLVTDGALDREQIPEYNVTITATDKGNPPLSSSKTITL 440
Query: 419 SVEDVNEWEPRFRHPQY 435
+ DVN+ P F Y
Sbjct: 441 HILDVNDNVPVFHQASY 457
Score = 77.0 bits (181), Expect = 3e-13
Identities = 83/293 (28%), Positives = 124/293 (42%), Gaps = 26/293 (8%)
Query: 5 AVESFFISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLL---R 61
A ES I ED +G+ + + + S G+I +L+ IV +KN L
Sbjct: 350 ASESQHIQEDAELGTAVALIKTHDLDSGFNGEILCQLKGN-FPFKIVQDTKNTYRLVTDG 408
Query: 62 ALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETX 121
ALDRE+ I NV + S I ++ + DVNDN P + A Y V V+E
Sbjct: 409 ALDREQ-IPEYNVTITATDKGNPPLSSSKTI--TLHILDVNDNVPVFHQASYTVHVAENN 465
Query: 122 XXXXXXXXXXXSDRDQPGPHSALHYAVL-----PGPHSEYLGFENELEPIIVVKKPLDFE 176
SD D GP+ + Y ++ P S Y+ ++ ++ D E
Sbjct: 466 PPGASIAHVRASDPDL-GPNGLVSYYIVASDLEPRELSSYVSVSAR-SGVVFAQRAFDHE 523
Query: 177 TVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTY----EHYTAL---LPDDAE 229
+ F + L+ +DQGSP L ++ +L+V V D +D P Y +AL +P AE
Sbjct: 524 QLRAFELTLQARDQGSPTLSANVSLRVLVDDRNDNAPLVLYPALGPEGSALFDMVPRSAE 583
Query: 230 EGTFLTTSPGPISAADQDLGINAPLQYSST-GDHKQLIVVNKDTGQVAATKQL 281
G +T + A D D G NA L Y L + TG+V + L
Sbjct: 584 PGYLVT----KVVAVDADSGYNAWLSYHIVQASEPGLFSLGLRTGEVRTARTL 632
Score = 52.8 bits (121), Expect = 5e-06
Identities = 41/163 (25%), Positives = 66/163 (40%), Gaps = 6/163 (3%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
V + + D NDNAP+ A + + E D D L L G
Sbjct: 333 VQIDISDENDNAPEITLASESQHIQEDAELGTAVALIKTHDLDSGFNGEIL--CQLKGNF 390
Query: 154 SEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNP 213
+ + + +V LD E + + + + D+G+PPL S T+ + +LD +D P
Sbjct: 391 PFKIVQDTKNTYRLVTDGALDREQIPEYNVTITATDKGNPPLSSSKTITLHILDVNDNVP 450
Query: 214 KFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQY 256
F YT + ++ G S + A+D DLG N + Y
Sbjct: 451 VFHQASYTVHVAENNPPG----ASIAHVRASDPDLGPNGLVSY 489
>AF152499-1|AAD43760.1| 794|Homo sapiens protocadherin beta 6
protein.
Length = 794
Score = 94.3 bits (224), Expect = 2e-18
Identities = 105/438 (23%), Positives = 177/438 (40%), Gaps = 26/438 (5%)
Query: 9 FFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAAVGIV--PGSKNLTLLRALDR 65
+ + E+T G+ + L+ + G +L R+ KG + P + +L L LDR
Sbjct: 32 YSVLEETESGTFVANLTKDLGLRVGELASRGARVVFKGNRQHLQFDPQTHDLLLNEKLDR 91
Query: 66 EEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXX 125
EE G + V + +P S+RV D+ND+AP++ +++SE
Sbjct: 92 EELCGSTEPCVLPF--QVLLENPLQFFQASLRVRDINDHAPEFPAREMLLKISEITMPGK 149
Query: 126 XXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLG---FENELEPIIVVKKPLDFETVNNFT 182
D D G + Y + PH L E P +V+ KPLD E
Sbjct: 150 IFPLKMAHDLDT-GSNGLQRYTISSNPHFHVLTRNRSEGRKFPELVLDKPLDREEQPQLR 208
Query: 183 IKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPIS 242
+ L D GSPP + +Q+ VLD +D P+F E Y A +P++ G+ + T +S
Sbjct: 209 LTLIALDGGSPPRSGTSEIQIQVLDINDNVPEFAQELYEAQVPENNPLGSLVIT----VS 264
Query: 243 AADQDLGINAPLQYS--STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDN 300
A D D G + Y+ D Q +N TG++ K L E S + ++AT D
Sbjct: 265 ARDLDAGSFGKVSYALFQVDDVNQPFEINAITGEIRLRKALDFEEIQSYDVDVEAT--DG 322
Query: 301 PDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFR 360
+L + T + + + E P + + ++
Sbjct: 323 GGLSGKCSLVVRVLDVNDNAP-----ELTMSFFISLIPENL-PEITVAVFSVSDADSGHN 376
Query: 361 ESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSIS---NDTASIN 417
+ + ++ FL + ++ N ++ +LD E+ + Y + VTD + SI
Sbjct: 377 QQVICSIENNLPFLLRPSVENFYTLVTEGALDRESRAEYNITITVTDLGTPRLKTQQSIT 436
Query: 418 ISVEDVNEWEPRFRHPQY 435
+ V DVN+ P F Y
Sbjct: 437 VQVSDVNDNVPAFTQTSY 454
Score = 74.9 bits (176), Expect = 1e-12
Identities = 68/229 (29%), Positives = 106/229 (46%), Gaps = 20/229 (8%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLP--G 151
++V+V DVNDN P + Y + V E +DRD G ++ + Y++LP
Sbjct: 435 ITVQVSDVNDNVPAFTQTSYTLFVRENNSPALHIGSVSATDRDS-GINAQVTYSLLPPQD 493
Query: 152 PH---SEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDA 208
PH S + + + ++ LD+E + +F ++ D+GSP L S+ +++ VLDA
Sbjct: 494 PHLPLSSLVSINADNGHLFALRS-LDYEALQSFEFRVGATDRGSPALSSEALVRLLVLDA 552
Query: 209 DDQNPKFTY------EHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYS-STGD 261
+D +P Y T L+P AE G +T + A D D G NA L Y
Sbjct: 553 NDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVT----KVVAVDGDSGQNAWLSYQLLKAT 608
Query: 262 HKQLIVVNKDTGQVAATKQLIAELDPSV-TIVLKATQVDNPDRYALATL 309
L V G+V T +L++E D + +V+ P R A ATL
Sbjct: 609 ELGLFGVWAHNGEV-RTARLLSERDAAKHRLVVLVKDNGEPPRSATATL 656
Score = 66.9 bits (156), Expect = 3e-10
Identities = 99/409 (24%), Positives = 157/409 (38%), Gaps = 24/409 (5%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRL---QEKGAAVGIVPGSKNLTLLRALDREE 67
+ E+ P+GS++ T+S + G ++ L + I + + L +ALD EE
Sbjct: 250 VPENNPLGSLVITVSARDLDAGSFGKVSYALFQVDDVNQPFEINAITGEIRLRKALDFEE 309
Query: 68 KIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXX 127
I +V V + S V VRV DVNDNAP+ + + + E
Sbjct: 310 -IQSYDVDVEATDGGGLSGKCSLV----VRVLDVNDNAPELTMSFFISLIPENLPEITVA 364
Query: 128 XXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRV 187
SD D + P EN +V + LD E+ + I + V
Sbjct: 365 VFSV-SDADSGHNQQVICSIENNLPFLLRPSVENFYT--LVTEGALDRESRAEYNITITV 421
Query: 188 QDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQD 247
D G+P L + ++ V V D +D P FT YT + ++ + G +SA D+D
Sbjct: 422 TDLGTPRLKTQQSITVQVSDVNDNVPAFTQTSYTLFVRENNSPALHI----GSVSATDRD 477
Query: 248 LGINAPLQYS---STGDH---KQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNP 301
GINA + YS H L+ +N D G + A + L E S + AT +P
Sbjct: 478 SGINAQVTYSLLPPQDPHLPLSSLVSINADNGHLFALRSLDYEALQSFEFRVGATDRGSP 537
Query: 302 DRYALATLXXXXXXXXXXX-XXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFR 360
+ A + LQ + V A PG L+T +
Sbjct: 538 ALSSEALVRLLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPG-YLVTKVVAVDGDSGQ 596
Query: 361 ESPLQFYVSDRSFLDKFAI-NNAGEVILRRSLDYETTSNYFYQVMVTDS 408
+ L + + + L F + + GEV R L + + V+V D+
Sbjct: 597 NAWLSYQLLKATELGLFGVWAHNGEVRTARLLSERDAAKHRLVVLVKDN 645
>AF152484-1|AAD43745.1| 803|Homo sapiens protocadherin alpha 6
short form protein protein.
Length = 803
Score = 94.3 bits (224), Expect = 2e-18
Identities = 95/390 (24%), Positives = 166/390 (42%), Gaps = 26/390 (6%)
Query: 57 LTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVR 116
L L ++LDREE P++ D + + + + + V V DVNDNAP +E + Y VR
Sbjct: 194 LLLKKSLDREE--APAHNLFLTATDGGKP-ELTGTVQLLVTVLDVNDNAPTFEQSEYEVR 250
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYA---VLPGPHSEYLGFENELEPIIVVKKPL 173
+ E SDRD+ G + A+ Y+ ++ ++ + I V++ L
Sbjct: 251 IFENADNGTTVIRLNASDRDE-GANGAISYSFNSLVAAMVIDHFSIDRNTGEI-VIRGNL 308
Query: 174 DFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTF 233
DFE N + I + D+G PP+ T+ V +LD +D P+ + + +DA+ GT
Sbjct: 309 DFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTV 368
Query: 234 LTTSPGPISAADQDLGINAPLQYSSTGDHK-QLIVVNKDTGQVAATKQLIAELDPSVTIV 292
+ IS D D G N + S T +L+ K+ + L E + +V
Sbjct: 369 IAL----ISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELV 424
Query: 293 LKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTT 352
+ A +P +A A+L F Q +Y+ V E PG + T++
Sbjct: 425 VTARDGGSPSLWATASLSVEVADMNDNAPA-----FAQPEYTVFVKENNPPGCHIFTVSA 479
Query: 353 ----VPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTD 407
+N S ++ V +R+ +++ +G+V + LD+E +QV D
Sbjct: 480 RDADAQENALVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARD 539
Query: 408 S---ISNDTASINISVEDVNEWEPRFRHPQ 434
+ ++ + V D N+ P P+
Sbjct: 540 AGVPPLGSNVTLQVFVLDENDNAPALLAPR 569
Score = 90.6 bits (215), Expect = 2e-17
Identities = 98/389 (25%), Positives = 158/389 (40%), Gaps = 34/389 (8%)
Query: 63 LDREEKIGPS---NVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSE 119
+DREE G S ++++ V DR P V V V V D+NDN P + V + E
Sbjct: 90 IDREELCGRSAECSIHLEVIVDR-----PLQVFHVDVEVRDINDNPPLFPVEEQRVLIYE 144
Query: 120 TXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPI------IVVKKPL 173
+ SD D G +S L Y + SEY G + ++ +++KK L
Sbjct: 145 SRLPDSVFPLEGASDAD-VGSNSILTYKL---SSSEYFGLDVKINSDDNKQIGLLLKKSL 200
Query: 174 DFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTF 233
D E + L D G P L L VTVLD +D P F Y + ++A+ GT
Sbjct: 201 DREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEVRIFENADNGTT 260
Query: 234 LTTSPGPISAADQDLGINAPLQYSSTGDHKQLIV----VNKDTGQVAATKQLIAELDPSV 289
+ ++A+D+D G N + YS +++ ++++TG++ L E +
Sbjct: 261 VIR----LNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNLDFEQENLY 316
Query: 290 TIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLT 349
I++ AT +P T+ + S V E A G+V+
Sbjct: 317 KILIDATDKGHPPMAGHCTVLVRILDKNDNVP-----EIALTSLSLPVREDAQFGTVIAL 371
Query: 350 LTTVPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSI 409
++ ++ F N ++L +LD E+ S Y V D
Sbjct: 372 ISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGG 431
Query: 410 SND---TASINISVEDVNEWEPRFRHPQY 435
S TAS+++ V D+N+ P F P+Y
Sbjct: 432 SPSLWATASLSVEVADMNDNAPAFAQPEY 460
Score = 64.1 bits (149), Expect = 2e-09
Identities = 85/318 (26%), Positives = 121/318 (38%), Gaps = 30/318 (9%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKN---LTLLRALDREE 67
+ ED G++I +SVN S G + L +V KN L L ALDR E
Sbjct: 359 VREDAQFGTVIALISVNDLDSGANGQVNCSLTPH-VPFKLVSTFKNYYSLVLDSALDR-E 416
Query: 68 KIGPSNVYVNVRCDRRRTTDPSF--VIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXX 125
+ + V R PS +SV V D+NDNAP + Y V V E
Sbjct: 417 SVSAYELVVTA----RDGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGC 472
Query: 126 XXXXXXXSDRDQPG----PHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNF 181
D D +S + V S Y+ E + + +PLD E +
Sbjct: 473 HIFTVSARDADAQENALVSYSLVERRVGERALSSYISVHAESGKVYAL-QPLDHEELELL 531
Query: 182 TIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKF-------TYEHYTALLPDDAEEGTFL 234
++ +D G PPL S+ TLQV VLD +D P T + L+P G +
Sbjct: 532 QFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVV 591
Query: 235 TTSPGPISAADQDLGINAPLQYS---STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTI 291
+ A D D G NA L Y + V TG+++ T+ L P +
Sbjct: 592 ----AKVRAVDADSGYNAWLSYELQPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRL 647
Query: 292 VLKATQVDNPDRYALATL 309
++ P A AT+
Sbjct: 648 LVLVKDHGEPALTATATV 665
>AF152332-1|AAD43726.1| 929|Homo sapiens protocadherin gamma B3
protein.
Length = 929
Score = 94.3 bits (224), Expect = 2e-18
Identities = 105/437 (24%), Positives = 175/437 (40%), Gaps = 24/437 (5%)
Query: 9 FFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREE 67
+ I E+ GS++G L+ + G DL LR+ + + P + NL + +DREE
Sbjct: 35 YAIPEELDRGSLVGNLAKDLGFGVGDLPTRNLRVIAEKKFFTVSPENGNLLVSDRIDREE 94
Query: 68 KIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXX 127
G + V + + +F V+V + D+NDN P + + +SE
Sbjct: 95 ICGKKSTCV-LEFEMVAEKPLNF-FHVTVLIQDINDNPPTFSQNITELEISELALTGATF 152
Query: 128 XXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFEN---ELEPIIVVKKPLDFETVNNFTIK 184
D D G +S Y + P PH + EN P +V+K PLD E + +
Sbjct: 153 ALESAQDPDV-GVNSLQQYYLSPDPHFSLIQKENLDGSRYPELVLKAPLDREEQPHHHLV 211
Query: 185 LRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAA 244
L D G P T ++V V DA+D P FT + Y + ++ G +S + A
Sbjct: 212 LTAVDGGEPSRSCTTQIRVIVADANDNPPVFTQDMYRVNVAENLPAG----SSVLKVMAI 267
Query: 245 DQDLGINAPLQYSSTG---DHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNP 301
D D GINA + Y+ + +QL ++ TG++ +L E S TI ++A +
Sbjct: 268 DMDEGINAEIIYAFINIGKEVRQLFKLDSKTGELTTIGELDFEERDSYTIGVEAKDGGHH 327
Query: 302 DRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRE 361
Y + + T S + E A G+ + + T ++ F
Sbjct: 328 TAYCKVQIDISDENDNAP-------EITLASESQHIQEDAELGTAVALIKTHDLDSGFNG 380
Query: 362 SPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSIS---NDTASINI 418
L + F N ++ +LD E Y + TD + + + +I +
Sbjct: 381 EILCQLKGNFPFKIVQDTKNTYRLVTDGALDREQIPEYNVTITATDKGNPPLSSSKTITL 440
Query: 419 SVEDVNEWEPRFRHPQY 435
+ DVN+ P F Y
Sbjct: 441 HILDVNDNVPVFHQASY 457
Score = 77.0 bits (181), Expect = 3e-13
Identities = 83/293 (28%), Positives = 124/293 (42%), Gaps = 26/293 (8%)
Query: 5 AVESFFISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLL---R 61
A ES I ED +G+ + + + S G+I +L+ IV +KN L
Sbjct: 350 ASESQHIQEDAELGTAVALIKTHDLDSGFNGEILCQLKGN-FPFKIVQDTKNTYRLVTDG 408
Query: 62 ALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETX 121
ALDRE+ I NV + S I ++ + DVNDN P + A Y V V+E
Sbjct: 409 ALDREQ-IPEYNVTITATDKGNPPLSSSKTI--TLHILDVNDNVPVFHQASYTVHVAENN 465
Query: 122 XXXXXXXXXXXSDRDQPGPHSALHYAVL-----PGPHSEYLGFENELEPIIVVKKPLDFE 176
SD D GP+ + Y ++ P S Y+ ++ ++ D E
Sbjct: 466 PPGASIAHVRASDPDL-GPNGLVSYYIVASDLEPRELSSYVSVSAR-SGVVFAQRAFDHE 523
Query: 177 TVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTY----EHYTAL---LPDDAE 229
+ F + L+ +DQGSP L ++ +L+V V D +D P Y +AL +P AE
Sbjct: 524 QLRAFELTLQARDQGSPTLSANVSLRVLVDDRNDNAPLVLYPALGPEGSALFDMVPRSAE 583
Query: 230 EGTFLTTSPGPISAADQDLGINAPLQYSST-GDHKQLIVVNKDTGQVAATKQL 281
G +T + A D D G NA L Y L + TG+V + L
Sbjct: 584 PGYLVT----KVVAVDADSGYNAWLSYHIVQASEPGLFSLGLRTGEVRTARTL 632
Score = 52.8 bits (121), Expect = 5e-06
Identities = 41/163 (25%), Positives = 66/163 (40%), Gaps = 6/163 (3%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
V + + D NDNAP+ A + + E D D L L G
Sbjct: 333 VQIDISDENDNAPEITLASESQHIQEDAELGTAVALIKTHDLDSGFNGEIL--CQLKGNF 390
Query: 154 SEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNP 213
+ + + +V LD E + + + + D+G+PPL S T+ + +LD +D P
Sbjct: 391 PFKIVQDTKNTYRLVTDGALDREQIPEYNVTITATDKGNPPLSSSKTITLHILDVNDNVP 450
Query: 214 KFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQY 256
F YT + ++ G S + A+D DLG N + Y
Sbjct: 451 VFHQASYTVHVAENNPPG----ASIAHVRASDPDLGPNGLVSY 489
>AF152314-1|AAD43708.1| 950|Homo sapiens protocadherin alpha 6
protein.
Length = 950
Score = 94.3 bits (224), Expect = 2e-18
Identities = 95/390 (24%), Positives = 166/390 (42%), Gaps = 26/390 (6%)
Query: 57 LTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVR 116
L L ++LDREE P++ D + + + + + V V DVNDNAP +E + Y VR
Sbjct: 194 LLLKKSLDREE--APAHNLFLTATDGGKP-ELTGTVQLLVTVLDVNDNAPTFEQSEYEVR 250
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYA---VLPGPHSEYLGFENELEPIIVVKKPL 173
+ E SDRD+ G + A+ Y+ ++ ++ + I V++ L
Sbjct: 251 IFENADNGTTVIRLNASDRDE-GANGAISYSFNSLVAAMVIDHFSIDRNTGEI-VIRGNL 308
Query: 174 DFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTF 233
DFE N + I + D+G PP+ T+ V +LD +D P+ + + +DA+ GT
Sbjct: 309 DFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTV 368
Query: 234 LTTSPGPISAADQDLGINAPLQYSSTGDHK-QLIVVNKDTGQVAATKQLIAELDPSVTIV 292
+ IS D D G N + S T +L+ K+ + L E + +V
Sbjct: 369 IAL----ISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELV 424
Query: 293 LKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTT 352
+ A +P +A A+L F Q +Y+ V E PG + T++
Sbjct: 425 VTARDGGSPSLWATASLSVEVADMNDNAPA-----FAQPEYTVFVKENNPPGCHIFTVSA 479
Query: 353 ----VPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTD 407
+N S ++ V +R+ +++ +G+V + LD+E +QV D
Sbjct: 480 RDADAQENALVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARD 539
Query: 408 S---ISNDTASINISVEDVNEWEPRFRHPQ 434
+ ++ + V D N+ P P+
Sbjct: 540 AGVPPLGSNVTLQVFVLDENDNAPALLAPR 569
Score = 90.6 bits (215), Expect = 2e-17
Identities = 98/389 (25%), Positives = 158/389 (40%), Gaps = 34/389 (8%)
Query: 63 LDREEKIGPS---NVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSE 119
+DREE G S ++++ V DR P V V V V D+NDN P + V + E
Sbjct: 90 IDREELCGRSAECSIHLEVIVDR-----PLQVFHVDVEVRDINDNPPLFPVEEQRVLIYE 144
Query: 120 TXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPI------IVVKKPL 173
+ SD D G +S L Y + SEY G + ++ +++KK L
Sbjct: 145 SRLPDSVFPLEGASDAD-VGSNSILTYKL---SSSEYFGLDVKINSDDNKQIGLLLKKSL 200
Query: 174 DFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTF 233
D E + L D G P L L VTVLD +D P F Y + ++A+ GT
Sbjct: 201 DREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEVRIFENADNGTT 260
Query: 234 LTTSPGPISAADQDLGINAPLQYSSTGDHKQLIV----VNKDTGQVAATKQLIAELDPSV 289
+ ++A+D+D G N + YS +++ ++++TG++ L E +
Sbjct: 261 VIR----LNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNLDFEQENLY 316
Query: 290 TIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLT 349
I++ AT +P T+ + S V E A G+V+
Sbjct: 317 KILIDATDKGHPPMAGHCTVLVRILDKNDNVP-----EIALTSLSLPVREDAQFGTVIAL 371
Query: 350 LTTVPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSI 409
++ ++ F N ++L +LD E+ S Y V D
Sbjct: 372 ISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGG 431
Query: 410 SND---TASINISVEDVNEWEPRFRHPQY 435
S TAS+++ V D+N+ P F P+Y
Sbjct: 432 SPSLWATASLSVEVADMNDNAPAFAQPEY 460
Score = 64.1 bits (149), Expect = 2e-09
Identities = 85/318 (26%), Positives = 121/318 (38%), Gaps = 30/318 (9%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKN---LTLLRALDREE 67
+ ED G++I +SVN S G + L +V KN L L ALDR E
Sbjct: 359 VREDAQFGTVIALISVNDLDSGANGQVNCSLTPH-VPFKLVSTFKNYYSLVLDSALDR-E 416
Query: 68 KIGPSNVYVNVRCDRRRTTDPSF--VIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXX 125
+ + V R PS +SV V D+NDNAP + Y V V E
Sbjct: 417 SVSAYELVVTA----RDGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGC 472
Query: 126 XXXXXXXSDRDQPG----PHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNF 181
D D +S + V S Y+ E + + +PLD E +
Sbjct: 473 HIFTVSARDADAQENALVSYSLVERRVGERALSSYISVHAESGKVYAL-QPLDHEELELL 531
Query: 182 TIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKF-------TYEHYTALLPDDAEEGTFL 234
++ +D G PPL S+ TLQV VLD +D P T + L+P G +
Sbjct: 532 QFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVV 591
Query: 235 TTSPGPISAADQDLGINAPLQYS---STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTI 291
+ A D D G NA L Y + V TG+++ T+ L P +
Sbjct: 592 ----AKVRAVDADSGYNAWLSYELQPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRL 647
Query: 292 VLKATQVDNPDRYALATL 309
++ P A AT+
Sbjct: 648 LVLVKDHGEPALTATATV 665
>AC005609-8|AAC34320.1| 803|Homo sapiens KIAA0345-like 8 protein.
Length = 803
Score = 94.3 bits (224), Expect = 2e-18
Identities = 95/390 (24%), Positives = 166/390 (42%), Gaps = 26/390 (6%)
Query: 57 LTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVR 116
L L ++LDREE P++ D + + + + + V V DVNDNAP +E + Y VR
Sbjct: 194 LLLKKSLDREE--APAHNLFLTATDGGKP-ELTGTVQLLVTVLDVNDNAPTFEQSEYEVR 250
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYA---VLPGPHSEYLGFENELEPIIVVKKPL 173
+ E SDRD+ G + A+ Y+ ++ ++ + I V++ L
Sbjct: 251 IFENADNGTTVIRLNASDRDE-GANGAISYSFNSLVAAMVIDHFSIDRNTGEI-VIRGNL 308
Query: 174 DFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTF 233
DFE N + I + D+G PP+ T+ V +LD +D P+ + + +DA+ GT
Sbjct: 309 DFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTV 368
Query: 234 LTTSPGPISAADQDLGINAPLQYSSTGDHK-QLIVVNKDTGQVAATKQLIAELDPSVTIV 292
+ IS D D G N + S T +L+ K+ + L E + +V
Sbjct: 369 IAL----ISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELV 424
Query: 293 LKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTT 352
+ A +P +A A+L F Q +Y+ V E PG + T++
Sbjct: 425 VTARDGGSPSLWATASLSVEVADMNDNAPA-----FAQPEYTVFVKENNPPGCHIFTVSA 479
Query: 353 ----VPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTD 407
+N S ++ V +R+ +++ +G+V + LD+E +QV D
Sbjct: 480 RDADAQENALVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARD 539
Query: 408 S---ISNDTASINISVEDVNEWEPRFRHPQ 434
+ ++ + V D N+ P P+
Sbjct: 540 AGVPPLGSNVTLQVFVLDENDNAPALLAPR 569
Score = 90.6 bits (215), Expect = 2e-17
Identities = 98/389 (25%), Positives = 158/389 (40%), Gaps = 34/389 (8%)
Query: 63 LDREEKIGPS---NVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSE 119
+DREE G S ++++ V DR P V V V V D+NDN P + V + E
Sbjct: 90 IDREELCGRSAECSIHLEVIVDR-----PLQVFHVDVEVRDINDNPPLFPVEEQRVLIYE 144
Query: 120 TXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPI------IVVKKPL 173
+ SD D G +S L Y + SEY G + ++ +++KK L
Sbjct: 145 SRLPDSVFPLEGASDAD-VGSNSILTYKL---SSSEYFGLDVKINSDDNKQIGLLLKKSL 200
Query: 174 DFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTF 233
D E + L D G P L L VTVLD +D P F Y + ++A+ GT
Sbjct: 201 DREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEVRIFENADNGTT 260
Query: 234 LTTSPGPISAADQDLGINAPLQYSSTGDHKQLIV----VNKDTGQVAATKQLIAELDPSV 289
+ ++A+D+D G N + YS +++ ++++TG++ L E +
Sbjct: 261 VIR----LNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNLDFEQENLY 316
Query: 290 TIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLT 349
I++ AT +P T+ + S V E A G+V+
Sbjct: 317 KILIDATDKGHPPMAGHCTVLVRILDKNDNVP-----EIALTSLSLPVREDAQFGTVIAL 371
Query: 350 LTTVPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSI 409
++ ++ F N ++L +LD E+ S Y V D
Sbjct: 372 ISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGG 431
Query: 410 SND---TASINISVEDVNEWEPRFRHPQY 435
S TAS+++ V D+N+ P F P+Y
Sbjct: 432 SPSLWATASLSVEVADMNDNAPAFAQPEY 460
Score = 64.1 bits (149), Expect = 2e-09
Identities = 85/318 (26%), Positives = 121/318 (38%), Gaps = 30/318 (9%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKN---LTLLRALDREE 67
+ ED G++I +SVN S G + L +V KN L L ALDR E
Sbjct: 359 VREDAQFGTVIALISVNDLDSGANGQVNCSLTPH-VPFKLVSTFKNYYSLVLDSALDR-E 416
Query: 68 KIGPSNVYVNVRCDRRRTTDPSF--VIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXX 125
+ + V R PS +SV V D+NDNAP + Y V V E
Sbjct: 417 SVSAYELVVTA----RDGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGC 472
Query: 126 XXXXXXXSDRDQPG----PHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNF 181
D D +S + V S Y+ E + + +PLD E +
Sbjct: 473 HIFTVSARDADAQENALVSYSLVERRVGERALSSYISVHAESGKVYAL-QPLDHEELELL 531
Query: 182 TIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKF-------TYEHYTALLPDDAEEGTFL 234
++ +D G PPL S+ TLQV VLD +D P T + L+P G +
Sbjct: 532 QFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVV 591
Query: 235 TTSPGPISAADQDLGINAPLQYS---STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTI 291
+ A D D G NA L Y + V TG+++ T+ L P +
Sbjct: 592 ----AKVRAVDADSGYNAWLSYELQPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRL 647
Query: 292 VLKATQVDNPDRYALATL 309
++ P A AT+
Sbjct: 648 LVLVKDHGEPALTATATV 665
>BC071934-1|AAH71934.1| 798|Homo sapiens protocadherin beta 13
protein.
Length = 798
Score = 93.9 bits (223), Expect = 2e-18
Identities = 115/479 (24%), Positives = 187/479 (39%), Gaps = 33/479 (6%)
Query: 57 LTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVR 116
L L +ALDREE+ + + + + + S V + V DVNDNAP++E Y V+
Sbjct: 195 LVLDKALDREEE---AELRLTLTALDGGSPPRSGTAQVYIEVLDVNDNAPEFEQPFYRVQ 251
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPI---IVVKKPL 173
+SE +D D G + + Y++ SE +G ++ P+ I +KK L
Sbjct: 252 ISEDSPVGFLVVKVSATDVDT-GVNGEISYSLFQA--SEEIGKTFKINPLTGEIELKKQL 308
Query: 174 DFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTF 233
DFE + ++ + + +D G+ T+ + V+D +D P+ T +T+ +P++A E
Sbjct: 309 DFEKLQSYEVNIEARDAGT--FSGKCTVLIQVIDVNDHAPEVTMSAFTSPIPENAPE--- 363
Query: 234 LTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVL 293
T S +D D G N + S D L+ ++ + + L E I +
Sbjct: 364 --TVVALFSVSDLDSGENGKISCSIQEDLPFLLKSAENFYTLLTERPLDRESRAEYNITI 421
Query: 294 KATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPG----SVLLT 349
T + P + FTQ Y+ V E SP SV T
Sbjct: 422 TVTDLGTP-----MLITQLNMTVLIADVNDNAPAFTQTSYTLFVRENNSPALHIRSVSAT 476
Query: 350 LTTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTDS 408
N + S L +IN + G + RSLDYE + ++V +D
Sbjct: 477 DRDSGTNAQVTYSLLPPQDPHLPLTSLVSINADNGHLFALRSLDYEALQGFQFRVGASDH 536
Query: 409 IS---NDTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGDA 465
S + A + + V D N+ P +P VA DGD+
Sbjct: 537 GSPALSSEALVRVVVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVTKVVAVDGDS 596
Query: 466 GTLA-LS---LAGQHARMFYINASGDLFLREEAIGNLNSSSLHLVATAIDSGIPPRQTS 520
G A LS L +F + A + +++ LV D+G PPR +
Sbjct: 597 GQNAWLSYQLLKATELGLFGVWAHNGEVRTARLLSERDAAKHRLVVLVKDNGEPPRSAT 655
Score = 80.2 bits (189), Expect = 3e-14
Identities = 89/314 (28%), Positives = 138/314 (43%), Gaps = 27/314 (8%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNL-TLL--RALDREE 67
I E+ P +++ SV+ S + G I+ +QE ++ ++N TLL R LDRE
Sbjct: 357 IPENAP-ETVVALFSVSDLDSGENGKISCSIQED--LPFLLKSAENFYTLLTERPLDRES 413
Query: 68 KIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXX 127
+ + + + T + ++V + DVNDNAP + Y + V E
Sbjct: 414 R---AEYNITITVTDLGTPMLITQLNMTVLIADVNDNAPAFTQTSYTLFVRENNSPALHI 470
Query: 128 XXXXXSDRDQPGPHSALHYAVLP--GPHSEYLGFE--NELEPIIVVKKPLDFETVNNFTI 183
+DRD G ++ + Y++LP PH N + + LD+E + F
Sbjct: 471 RSVSATDRDS-GTNAQVTYSLLPPQDPHLPLTSLVSINADNGHLFALRSLDYEALQGFQF 529
Query: 184 KLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTY------EHYTALLPDDAEEGTFLTTS 237
++ D GSP L S+ ++V VLDA+D +P Y T L+P AE G +T
Sbjct: 530 RVGASDHGSPALSSEALVRVVVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVT-- 587
Query: 238 PGPISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPSV-TIVLKA 295
+ A D D G NA L Y L V G+V T +L++E D + +V+
Sbjct: 588 --KVVAVDGDSGQNAWLSYQLLKATELGLFGVWAHNGEV-RTARLLSERDAAKHRLVVLV 644
Query: 296 TQVDNPDRYALATL 309
P R A ATL
Sbjct: 645 KDNGEPPRSATATL 658
Score = 78.2 bits (184), Expect = 1e-13
Identities = 105/447 (23%), Positives = 181/447 (40%), Gaps = 32/447 (7%)
Query: 4 GAVE--SFFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLL 60
GA E S+ + E+T S + L+ + G + +R+ +G + + + LL
Sbjct: 27 GAAEPRSYSVVEETEGSSFVTNLAKDLGLEQREFSRRGVRVVSRGNKLHLQLNQETADLL 86
Query: 61 --RALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVS 118
LDRE+ G + V +R + P ++V D+ND++P + V+VS
Sbjct: 87 LNEKLDREDLCGHTEPCV-LRF-QVLLESPFEFFQAELQVIDINDHSPVFLDKQMLVKVS 144
Query: 119 ETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLG---FENELEPIIVVKKPLDF 175
E+ D D G ++ +Y + P + L + P +V+ K LD
Sbjct: 145 ESSPPGTTFPLKNAEDLDV-GQNNIENYIISPNSYFRVLTRKRSDGRKYPELVLDKALDR 203
Query: 176 ETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLT 235
E + L D GSPP + + VLD +D P+F Y + +D+ G FL
Sbjct: 204 EEEAELRLTLTALDGGSPPRSGTAQVYIEVLDVNDNAPEFEQPFYRVQISEDSPVG-FLV 262
Query: 236 TSPGPISAADQDLGINAPLQYS---STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIV 292
+SA D D G+N + YS ++ + + +N TG++ KQL E
Sbjct: 263 VK---VSATDVDTGVNGEISYSLFQASEEIGKTFKINPLTGEIELKKQLDFE-------K 312
Query: 293 LKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTT 352
L++ +V+ R A + T +++ + E A P +V + L +
Sbjct: 313 LQSYEVNIEARDAGTFSGKCTVLIQVIDVNDHAPEVTMSAFTSPIPENA-PETV-VALFS 370
Query: 353 VPQNTEFRESPLQFYV-SDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTD---S 408
V + + D FL K A N ++ R LD E+ + Y + VTD
Sbjct: 371 VSDLDSGENGKISCSIQEDLPFLLKSA-ENFYTLLTERPLDRESRAEYNITITVTDLGTP 429
Query: 409 ISNDTASINISVEDVNEWEPRFRHPQY 435
+ ++ + + DVN+ P F Y
Sbjct: 430 MLITQLNMTVLIADVNDNAPAFTQTSY 456
>BC051348-1|AAH51348.1| 798|Homo sapiens protocadherin beta 13
protein.
Length = 798
Score = 93.9 bits (223), Expect = 2e-18
Identities = 115/479 (24%), Positives = 187/479 (39%), Gaps = 33/479 (6%)
Query: 57 LTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVR 116
L L +ALDREE+ + + + + + S V + V DVNDNAP++E Y V+
Sbjct: 195 LVLDKALDREEE---AELRLTLTALDGGSPPRSGTAQVYIEVLDVNDNAPEFEQPFYRVQ 251
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPI---IVVKKPL 173
+SE +D D G + + Y++ SE +G ++ P+ I +KK L
Sbjct: 252 ISEDSPVGFLVVKVSATDVDT-GVNGEISYSLFQA--SEEIGKTFKINPLTGEIELKKQL 308
Query: 174 DFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTF 233
DFE + ++ + + +D G+ T+ + V+D +D P+ T +T+ +P++A E
Sbjct: 309 DFEKLQSYEVNIEARDAGT--FSGKCTVLIQVIDVNDHAPEVTMSAFTSPIPENAPE--- 363
Query: 234 LTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVL 293
T S +D D G N + S D L+ ++ + + L E I +
Sbjct: 364 --TVVALFSVSDLDSGENGKISCSIQEDLPFLLKSAENFYTLLTERPLDRESRAEYNITI 421
Query: 294 KATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPG----SVLLT 349
T + P + FTQ Y+ V E SP SV T
Sbjct: 422 TVTDLGTP-----MLITQLNMTVLIADVNDNAPAFTQTSYTLFVRENNSPALHIRSVSAT 476
Query: 350 LTTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTDS 408
N + S L +IN + G + RSLDYE + ++V +D
Sbjct: 477 DRDSGTNAQVTYSLLPPQDPHLPLTSLVSINADNGHLFALRSLDYEALQGFQFRVGASDH 536
Query: 409 IS---NDTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGDA 465
S + A + + V D N+ P +P VA DGD+
Sbjct: 537 GSPALSSEALVRVVVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVTKVVAVDGDS 596
Query: 466 GTLA-LS---LAGQHARMFYINASGDLFLREEAIGNLNSSSLHLVATAIDSGIPPRQTS 520
G A LS L +F + A + +++ LV D+G PPR +
Sbjct: 597 GQNAWLSYQLLKATELGLFGVWAHNGEVRTARLLSERDAAKHRLVVLVKDNGEPPRSAT 655
Score = 80.2 bits (189), Expect = 3e-14
Identities = 89/314 (28%), Positives = 138/314 (43%), Gaps = 27/314 (8%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNL-TLL--RALDREE 67
I E+ P +++ SV+ S + G I+ +QE ++ ++N TLL R LDRE
Sbjct: 357 IPENAP-ETVVALFSVSDLDSGENGKISCSIQED--LPFLLKSAENFYTLLTERPLDRES 413
Query: 68 KIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXX 127
+ + + + T + ++V + DVNDNAP + Y + V E
Sbjct: 414 R---AEYNITITVTDLGTPMLITQLNMTVLIADVNDNAPAFTQTSYTLFVRENNSPALHI 470
Query: 128 XXXXXSDRDQPGPHSALHYAVLP--GPHSEYLGFE--NELEPIIVVKKPLDFETVNNFTI 183
+DRD G ++ + Y++LP PH N + + LD+E + F
Sbjct: 471 RSVSATDRDS-GTNAQVTYSLLPPQDPHLPLTSLVSINADNGHLFALRSLDYEALQGFQF 529
Query: 184 KLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTY------EHYTALLPDDAEEGTFLTTS 237
++ D GSP L S+ ++V VLDA+D +P Y T L+P AE G +T
Sbjct: 530 RVGASDHGSPALSSEALVRVVVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVT-- 587
Query: 238 PGPISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPSV-TIVLKA 295
+ A D D G NA L Y L V G+V T +L++E D + +V+
Sbjct: 588 --KVVAVDGDSGQNAWLSYQLLKATELGLFGVWAHNGEV-RTARLLSERDAAKHRLVVLV 644
Query: 296 TQVDNPDRYALATL 309
P R A ATL
Sbjct: 645 KDNGEPPRSATATL 658
Score = 78.2 bits (184), Expect = 1e-13
Identities = 105/447 (23%), Positives = 181/447 (40%), Gaps = 32/447 (7%)
Query: 4 GAVE--SFFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLL 60
GA E S+ + E+T S + L+ + G + +R+ +G + + + LL
Sbjct: 27 GAAEPRSYSVVEETEGSSFVTNLAKDLGLEQREFSRRGVRVVSRGNKLHLQLNQETADLL 86
Query: 61 --RALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVS 118
LDRE+ G + V +R + P ++V D+ND++P + V+VS
Sbjct: 87 LNEKLDREDLCGHTEPCV-LRF-QVLLESPFEFFQAELQVIDINDHSPVFLDKQMLVKVS 144
Query: 119 ETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLG---FENELEPIIVVKKPLDF 175
E+ D D G ++ +Y + P + L + P +V+ K LD
Sbjct: 145 ESSPPGTTFPLKNAEDLDV-GQNNIENYIISPNSYFRVLTRKRSDGRKYPELVLDKALDR 203
Query: 176 ETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLT 235
E + L D GSPP + + VLD +D P+F Y + +D+ G FL
Sbjct: 204 EEEAELRLTLTALDGGSPPRSGTAQVYIEVLDVNDNAPEFEQPFYRVQISEDSPVG-FLV 262
Query: 236 TSPGPISAADQDLGINAPLQYS---STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIV 292
+SA D D G+N + YS ++ + + +N TG++ KQL E
Sbjct: 263 VK---VSATDVDTGVNGEISYSLFQASEEIGKTFKINPLTGEIELKKQLDFE-------K 312
Query: 293 LKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTT 352
L++ +V+ R A + T +++ + E A P +V + L +
Sbjct: 313 LQSYEVNIEARDAGTFSGKCTVLIQVIDVNDHAPEVTMSAFTSPIPENA-PETV-VALFS 370
Query: 353 VPQNTEFRESPLQFYV-SDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTD---S 408
V + + D FL K A N ++ R LD E+ + Y + VTD
Sbjct: 371 VSDLDSGENGKISCSIQEDLPFLLKSA-ENFYTLLTERPLDRESRAEYNITITVTDLGTP 429
Query: 409 ISNDTASINISVEDVNEWEPRFRHPQY 435
+ ++ + + DVN+ P F Y
Sbjct: 430 MLITQLNMTVLIADVNDNAPAFTQTSY 456
>BC033068-1|AAH33068.1| 798|Homo sapiens protocadherin beta 13
protein.
Length = 798
Score = 93.9 bits (223), Expect = 2e-18
Identities = 115/479 (24%), Positives = 187/479 (39%), Gaps = 33/479 (6%)
Query: 57 LTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVR 116
L L +ALDREE+ + + + + + S V + V DVNDNAP++E Y V+
Sbjct: 195 LVLDKALDREEE---AELRLTLTALDGGSPPRSGTAQVYIEVLDVNDNAPEFEQPFYRVQ 251
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPI---IVVKKPL 173
+SE +D D G + + Y++ SE +G ++ P+ I +KK L
Sbjct: 252 ISEDSPVGFLVVKVSATDVDT-GVNGEISYSLFQA--SEEIGKTFKINPLTGEIELKKQL 308
Query: 174 DFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTF 233
DFE + ++ + + +D G+ T+ + V+D +D P+ T +T+ +P++A E
Sbjct: 309 DFEKLQSYEVNIEARDAGT--FSGKCTVLIQVIDVNDHAPEVTMSAFTSPIPENAPE--- 363
Query: 234 LTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVL 293
T S +D D G N + S D L+ ++ + + L E I +
Sbjct: 364 --TVVALFSVSDLDSGENGKISCSIQEDLPFLLKSAENFYTLLTERPLDRESRAEYNITI 421
Query: 294 KATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPG----SVLLT 349
T + P + FTQ Y+ V E SP SV T
Sbjct: 422 TVTDLGTP-----MLITQLNMTVLIADVNDNAPAFTQTSYTLFVRENNSPALHIRSVSAT 476
Query: 350 LTTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTDS 408
N + S L +IN + G + RSLDYE + ++V +D
Sbjct: 477 DRDSGTNAQVTYSLLPPQDPHLPLTSLVSINADNGHLFALRSLDYEALQGFQFRVGASDH 536
Query: 409 IS---NDTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGDA 465
S + A + + V D N+ P +P VA DGD+
Sbjct: 537 GSPALSSEALVRVVVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVTKVVAVDGDS 596
Query: 466 GTLA-LS---LAGQHARMFYINASGDLFLREEAIGNLNSSSLHLVATAIDSGIPPRQTS 520
G A LS L +F + A + +++ LV D+G PPR +
Sbjct: 597 GQNAWLSYQLLKATELGLFGVWAHNGEVRTARLLSERDAAKHRLVVLVKDNGEPPRSAT 655
Score = 80.2 bits (189), Expect = 3e-14
Identities = 89/314 (28%), Positives = 138/314 (43%), Gaps = 27/314 (8%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNL-TLL--RALDREE 67
I E+ P +++ SV+ S + G I+ +QE ++ ++N TLL R LDRE
Sbjct: 357 IPENAP-ETVVALFSVSDLDSGENGKISCSIQED--LPFLLKSAENFYTLLTERPLDRES 413
Query: 68 KIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXX 127
+ + + + T + ++V + DVNDNAP + Y + V E
Sbjct: 414 R---AEYNITITVTDLGTPMLITQLNMTVLIADVNDNAPAFTQTSYTLFVRENNSPALHI 470
Query: 128 XXXXXSDRDQPGPHSALHYAVLP--GPHSEYLGFE--NELEPIIVVKKPLDFETVNNFTI 183
+DRD G ++ + Y++LP PH N + + LD+E + F
Sbjct: 471 RSVSATDRDS-GTNAQVTYSLLPPQDPHLPLTSLVSINADNGHLFALRSLDYEALQGFQF 529
Query: 184 KLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTY------EHYTALLPDDAEEGTFLTTS 237
++ D GSP L S+ ++V VLDA+D +P Y T L+P AE G +T
Sbjct: 530 RVGASDHGSPALSSEALVRVVVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVT-- 587
Query: 238 PGPISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPSV-TIVLKA 295
+ A D D G NA L Y L V G+V T +L++E D + +V+
Sbjct: 588 --KVVAVDGDSGQNAWLSYQLLKATELGLFGVWAHNGEV-RTARLLSERDAAKHRLVVLV 644
Query: 296 TQVDNPDRYALATL 309
P R A ATL
Sbjct: 645 KDNGEPPRSATATL 658
Score = 78.2 bits (184), Expect = 1e-13
Identities = 105/447 (23%), Positives = 181/447 (40%), Gaps = 32/447 (7%)
Query: 4 GAVE--SFFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLL 60
GA E S+ + E+T S + L+ + G + +R+ +G + + + LL
Sbjct: 27 GAAEPRSYSVVEETEGSSFVTNLAKDLGLEQREFSRRGVRVVSRGNKLHLQLNQETADLL 86
Query: 61 --RALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVS 118
LDRE+ G + V +R + P ++V D+ND++P + V+VS
Sbjct: 87 LNEKLDREDLCGHTEPCV-LRF-QVLLESPFEFFQAELQVIDINDHSPVFLDKQMLVKVS 144
Query: 119 ETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLG---FENELEPIIVVKKPLDF 175
E+ D D G ++ +Y + P + L + P +V+ K LD
Sbjct: 145 ESSPPGTTFPLKNAEDLDV-GQNNIENYIISPNSYFRVLTRKRSDGRKYPELVLDKALDR 203
Query: 176 ETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLT 235
E + L D GSPP + + VLD +D P+F Y + +D+ G FL
Sbjct: 204 EEEAELRLTLTALDGGSPPRSGTAQVYIEVLDVNDNAPEFEQPFYRVQISEDSPVG-FLV 262
Query: 236 TSPGPISAADQDLGINAPLQYS---STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIV 292
+SA D D G+N + YS ++ + + +N TG++ KQL E
Sbjct: 263 VK---VSATDVDTGVNGEISYSLFQASEEIGKTFKINPLTGEIELKKQLDFE-------K 312
Query: 293 LKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTT 352
L++ +V+ R A + T +++ + E A P +V + L +
Sbjct: 313 LQSYEVNIEARDAGTFSGKCTVLIQVIDVNDHAPEVTMSAFTSPIPENA-PETV-VALFS 370
Query: 353 VPQNTEFRESPLQFYV-SDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTD---S 408
V + + D FL K A N ++ R LD E+ + Y + VTD
Sbjct: 371 VSDLDSGENGKISCSIQEDLPFLLKSA-ENFYTLLTERPLDRESRAEYNITITVTDLGTP 429
Query: 409 ISNDTASINISVEDVNEWEPRFRHPQY 435
+ ++ + + DVN+ P F Y
Sbjct: 430 MLITQLNMTVLIADVNDNAPAFTQTSY 456
>AY358946-1|AAQ89305.1| 916|Homo sapiens cadherin FIB3 protein.
Length = 916
Score = 93.9 bits (223), Expect = 2e-18
Identities = 109/441 (24%), Positives = 180/441 (40%), Gaps = 30/441 (6%)
Query: 9 FFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAA--VGIVPGSKNLTLLRALDR 65
+ + E+ GS +G +S + G +L + +R+ +G + P S +L +DR
Sbjct: 33 YSVPEELEKGSRVGDISRDLGLEPRELAERGVRIIPRGRTQLFALNPRSGSLVTAGRIDR 92
Query: 66 EEK-IGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXX 124
EE +G +N+ D + V V V D+NDNAP + + +++SE
Sbjct: 93 EELCMGAIKCQLNLDI---LMEDKVKIYGVEVEVRDINDNAPYFRESELEIKISENAATE 149
Query: 125 XXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYL---GFENELEPIIVVKKPLDFETVNNF 181
D D G +S Y + P H + G + P +V+K+ LD E
Sbjct: 150 MRFPLPHAWDPDI-GKNSLQSYELSPNTHFSLIVQNGADGSKYPELVLKRALDREEKAAH 208
Query: 182 TIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPI 241
+ L D G P ++V VLDA+D P F Y A +P++ GT L +
Sbjct: 209 HLVLTASDGGDPVRTGTARIRVMVLDANDNAPAFAQPEYRASVPENLALGTQLLV----V 264
Query: 242 SAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELD--PSVTIVLKATQV 298
+A D D G+NA ++YS D K V D + T I ELD S ++ +
Sbjct: 265 NATDPDEGVNAEVRYSFRYVDDKAAQVFKLDCN--SGTISTIGELDHEESGFYQMEVQAM 322
Query: 299 DNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTE 358
DN A A + + +++V E + G+++ L Q++E
Sbjct: 323 DNAGYSARAKVLITVLDVNDNAP-----EVVLTSLASSVPENSPRGTLIALLNVNDQDSE 377
Query: 359 FRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTD----SISNDTA 414
+ F + F + + N ++ LD E +Y V TD +S +T
Sbjct: 378 ENGQVICFIQGNLPFKLEKSYGNYYSLVTDIVLDREQVPSYNITVTATDRGTPPLSTET- 436
Query: 415 SINISVEDVNEWEPRFRHPQY 435
I+++V D N+ P F Y
Sbjct: 437 HISLNVADTNDNPPVFPQASY 457
Score = 74.5 bits (175), Expect = 1e-12
Identities = 79/313 (25%), Positives = 123/313 (39%), Gaps = 22/313 (7%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLR--ALDREEK 68
+ E++P G++I L+VN SE+ G + +Q +L+ LDRE+
Sbjct: 356 VPENSPRGTLIALLNVNDQDSEENGQVICFIQGNLPFKLEKSYGNYYSLVTDIVLDREQV 415
Query: 69 IGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXX 128
PS + V R T S +S+ V D NDN P + A Y+ + E
Sbjct: 416 --PS-YNITVTATDRGTPPLSTETHISLNVADTNDNPPVFPQASYSAYIPENNPRGVSLV 472
Query: 129 XXXXSDRDQPG----PHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIK 184
D D +S + S Y+ ++ ++ D+E + +K
Sbjct: 473 SVTAHDPDCEENAQITYSLAENTIQGASLSSYVSINSDTG-VLYALSSFDYEQFRDLQVK 531
Query: 185 LRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFL---TTSPG-- 239
+ +D G PPL S+ +L + VLD +D P+ Y LP D G L + PG
Sbjct: 532 VMARDNGHPPLSSNVSLSLFVLDQNDNAPEILY----PALPTDGSTGVELAPRSAEPGYL 587
Query: 240 --PISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKAT 296
+ A D+D G NA L Y L V TG+V + L+ ++V+
Sbjct: 588 VTKVVAVDRDSGQNAWLSYRLLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQ 647
Query: 297 QVDNPDRYALATL 309
P A TL
Sbjct: 648 DHGQPPLSATVTL 660
Score = 63.3 bits (147), Expect = 4e-09
Identities = 51/190 (26%), Positives = 81/190 (42%), Gaps = 12/190 (6%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
V + V DVNDNAP+ A V E +D+D + + P
Sbjct: 333 VLITVLDVNDNAPEVVLTSLASSVPENSPRGTLIALLNVNDQDSEENGQVICFIQGNLPF 392
Query: 154 SEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNP 213
+ N +V LD E V ++ I + D+G+PPL ++T + + V D +D P
Sbjct: 393 KLEKSYGNYYS--LVTDIVLDREQVPSYNITVTATDRGTPPLSTETHISLNVADTNDNPP 450
Query: 214 KFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQ------LIV 267
F Y+A +P++ G L + ++A D D NA + YS + Q +
Sbjct: 451 VFPQASYSAYIPENNPRGVSLVS----VTAHDPDCEENAQITYSLAENTIQGASLSSYVS 506
Query: 268 VNKDTGQVAA 277
+N DTG + A
Sbjct: 507 INSDTGVLYA 516
Score = 38.3 bits (85), Expect = 0.12
Identities = 50/215 (23%), Positives = 86/215 (40%), Gaps = 13/215 (6%)
Query: 8 SFFISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQE---KGAAVG-IVPGSKNLTLLRAL 63
S +I E+ P G + +++ + E+ IT L E +GA++ V + + +L AL
Sbjct: 458 SAYIPENNPRGVSLVSVTAHDPDCEENAQITYSLAENTIQGASLSSYVSINSDTGVLYAL 517
Query: 64 DREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQ-------WEGAPYAVR 116
+ ++ V V S + +S+ V D NDNAP+ +G+
Sbjct: 518 SSFDYEQFRDLQVKVMARDNGHPPLSSNVSLSLFVLDQNDNAPEILYPALPTDGSTGVEL 577
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFE 176
+ DRD G ++ L Y +L + + LD +
Sbjct: 578 APRSAEPGYLVTKVVAVDRDS-GQNAWLSYRLLKASEPGLFSVGLHTGEVRTARALLDRD 636
Query: 177 TVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQ 211
+ ++ + VQD G PPL + TL V V D+ Q
Sbjct: 637 ALKQ-SLVVAVQDHGQPPLSATVTLTVAVADSIPQ 670
>AY358427-1|AAQ88793.1| 798|Homo sapiens PCDHB13 protein.
Length = 798
Score = 93.9 bits (223), Expect = 2e-18
Identities = 115/479 (24%), Positives = 187/479 (39%), Gaps = 33/479 (6%)
Query: 57 LTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVR 116
L L +ALDREE+ + + + + + S V + V DVNDNAP++E Y V+
Sbjct: 195 LVLDKALDREEE---AELRLTLTALDGGSPPRSGTAQVYIEVLDVNDNAPEFEQPFYRVQ 251
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPI---IVVKKPL 173
+SE +D D G + + Y++ SE +G ++ P+ I +KK L
Sbjct: 252 ISEDSPVGFLVVKVSATDVDT-GVNGEISYSLFQA--SEEIGKTFKINPLTGEIELKKQL 308
Query: 174 DFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTF 233
DFE + ++ + + +D G+ T+ + V+D +D P+ T +T+ +P++A E
Sbjct: 309 DFEKLQSYEVNIEARDAGT--FSGKCTVLIQVIDVNDHAPEVTMSAFTSPIPENAPE--- 363
Query: 234 LTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVL 293
T S +D D G N + S D L+ ++ + + L E I +
Sbjct: 364 --TVVALFSVSDLDSGENGKISCSIQEDLPFLLKSAENFYTLLTERPLDRESRAEYNITI 421
Query: 294 KATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPG----SVLLT 349
T + P + FTQ Y+ V E SP SV T
Sbjct: 422 TVTDLGTP-----MLITQLNMTVLIADVNDNAPAFTQTSYTLFVRENNSPALHIRSVSAT 476
Query: 350 LTTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTDS 408
N + S L +IN + G + RSLDYE + ++V +D
Sbjct: 477 DRDSGTNAQVTYSLLPPQDPHLPLTSLVSINADNGHLFALRSLDYEALQGFQFRVGASDH 536
Query: 409 IS---NDTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGDA 465
S + A + + V D N+ P +P VA DGD+
Sbjct: 537 GSPALSSEALVRVVVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVTKVVAVDGDS 596
Query: 466 GTLA-LS---LAGQHARMFYINASGDLFLREEAIGNLNSSSLHLVATAIDSGIPPRQTS 520
G A LS L +F + A + +++ LV D+G PPR +
Sbjct: 597 GQNAWLSYQLLKATELGLFGVWAHNGEVRTARLLSERDAAKHRLVVLVKDNGEPPRSAT 655
Score = 80.2 bits (189), Expect = 3e-14
Identities = 89/314 (28%), Positives = 138/314 (43%), Gaps = 27/314 (8%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNL-TLL--RALDREE 67
I E+ P +++ SV+ S + G I+ +QE ++ ++N TLL R LDRE
Sbjct: 357 IPENAP-ETVVALFSVSDLDSGENGKISCSIQED--LPFLLKSAENFYTLLTERPLDRES 413
Query: 68 KIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXX 127
+ + + + T + ++V + DVNDNAP + Y + V E
Sbjct: 414 R---AEYNITITVTDLGTPMLITQLNMTVLIADVNDNAPAFTQTSYTLFVRENNSPALHI 470
Query: 128 XXXXXSDRDQPGPHSALHYAVLP--GPHSEYLGFE--NELEPIIVVKKPLDFETVNNFTI 183
+DRD G ++ + Y++LP PH N + + LD+E + F
Sbjct: 471 RSVSATDRDS-GTNAQVTYSLLPPQDPHLPLTSLVSINADNGHLFALRSLDYEALQGFQF 529
Query: 184 KLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTY------EHYTALLPDDAEEGTFLTTS 237
++ D GSP L S+ ++V VLDA+D +P Y T L+P AE G +T
Sbjct: 530 RVGASDHGSPALSSEALVRVVVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVT-- 587
Query: 238 PGPISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPSV-TIVLKA 295
+ A D D G NA L Y L V G+V T +L++E D + +V+
Sbjct: 588 --KVVAVDGDSGQNAWLSYQLLKATELGLFGVWAHNGEV-RTARLLSERDAAKHRLVVLV 644
Query: 296 TQVDNPDRYALATL 309
P R A ATL
Sbjct: 645 KDNGEPPRSATATL 658
Score = 78.2 bits (184), Expect = 1e-13
Identities = 105/447 (23%), Positives = 181/447 (40%), Gaps = 32/447 (7%)
Query: 4 GAVE--SFFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLL 60
GA E S+ + E+T S + L+ + G + +R+ +G + + + LL
Sbjct: 27 GAAEPRSYSVVEETEGSSFVTNLAKDLGLEQREFSRRGVRVVSRGNKLHLQLNQETADLL 86
Query: 61 --RALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVS 118
LDRE+ G + V +R + P ++V D+ND++P + V+VS
Sbjct: 87 LNEKLDREDLCGHTEPCV-LRF-QVLLESPFEFFQAELQVIDINDHSPVFLDKQMLVKVS 144
Query: 119 ETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLG---FENELEPIIVVKKPLDF 175
E+ D D G ++ +Y + P + L + P +V+ K LD
Sbjct: 145 ESSPPGTTFPLKNAEDLDV-GQNNIENYIISPNSYFRVLTRKRSDGRKYPELVLDKALDR 203
Query: 176 ETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLT 235
E + L D GSPP + + VLD +D P+F Y + +D+ G FL
Sbjct: 204 EEEAELRLTLTALDGGSPPRSGTAQVYIEVLDVNDNAPEFEQPFYRVQISEDSPVG-FLV 262
Query: 236 TSPGPISAADQDLGINAPLQYS---STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIV 292
+SA D D G+N + YS ++ + + +N TG++ KQL E
Sbjct: 263 VK---VSATDVDTGVNGEISYSLFQASEEIGKTFKINPLTGEIELKKQLDFE-------K 312
Query: 293 LKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTT 352
L++ +V+ R A + T +++ + E A P +V + L +
Sbjct: 313 LQSYEVNIEARDAGTFSGKCTVLIQVIDVNDHAPEVTMSAFTSPIPENA-PETV-VALFS 370
Query: 353 VPQNTEFRESPLQFYV-SDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTD---S 408
V + + D FL K A N ++ R LD E+ + Y + VTD
Sbjct: 371 VSDLDSGENGKISCSIQEDLPFLLKSA-ENFYTLLTERPLDRESRAEYNITITVTDLGTP 429
Query: 409 ISNDTASINISVEDVNEWEPRFRHPQY 435
+ ++ + + DVN+ P F Y
Sbjct: 430 MLITQLNMTVLIADVNDNAPAFTQTSY 456
>AF217745-1|AAK51613.1| 798|Homo sapiens protocadherin-beta13
protein.
Length = 798
Score = 93.9 bits (223), Expect = 2e-18
Identities = 115/479 (24%), Positives = 187/479 (39%), Gaps = 33/479 (6%)
Query: 57 LTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVR 116
L L +ALDREE+ + + + + + S V + V DVNDNAP++E Y V+
Sbjct: 195 LVLDKALDREEE---AELRLTLTALDGGSPPRSGTAQVYIEVLDVNDNAPEFEQPFYRVQ 251
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPI---IVVKKPL 173
+SE +D D G + + Y++ SE +G ++ P+ I +KK L
Sbjct: 252 ISEDSPVGFLVVKVSATDVDT-GVNGEISYSLFQA--SEEIGKTFKINPLTGEIELKKQL 308
Query: 174 DFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTF 233
DFE + ++ + + +D G+ T+ + V+D +D P+ T +T+ +P++A E
Sbjct: 309 DFEKLQSYEVNIEARDAGT--FSGKCTVLIQVIDVNDHAPEVTMSAFTSPIPENAPE--- 363
Query: 234 LTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVL 293
T S +D D G N + S D L+ ++ + + L E I +
Sbjct: 364 --TVVALFSVSDLDSGENGKISCSIQEDLPFLLKSAENFYTLLTERPLDRESRAEYNITI 421
Query: 294 KATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPG----SVLLT 349
T + P + FTQ Y+ V E SP SV T
Sbjct: 422 TVTDLGTP-----MLITQLNMTVLIADVNDNAPAFTQTSYTLFVRENNSPALHIRSVSAT 476
Query: 350 LTTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTDS 408
N + S L +IN + G + RSLDYE + ++V +D
Sbjct: 477 DRDSGTNAQVTYSLLPPQDPHLPLTSLVSINADNGHLFALRSLDYEALQGFQFRVGASDH 536
Query: 409 IS---NDTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGDA 465
S + A + + V D N+ P +P VA DGD+
Sbjct: 537 GSPALSSEALVRVVVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVTKVVAVDGDS 596
Query: 466 GTLA-LS---LAGQHARMFYINASGDLFLREEAIGNLNSSSLHLVATAIDSGIPPRQTS 520
G A LS L +F + A + +++ LV D+G PPR +
Sbjct: 597 GQNAWLSYQLLKATELGLFGVWAHNGEVRTARLLSERDAAKHRLVVLVKDNGEPPRSAT 655
Score = 80.2 bits (189), Expect = 3e-14
Identities = 89/314 (28%), Positives = 138/314 (43%), Gaps = 27/314 (8%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNL-TLL--RALDREE 67
I E+ P +++ SV+ S + G I+ +QE ++ ++N TLL R LDRE
Sbjct: 357 IPENAP-ETVVALFSVSDLDSGENGKISCSIQED--LPFLLKSAENFYTLLTERPLDRES 413
Query: 68 KIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXX 127
+ + + + T + ++V + DVNDNAP + Y + V E
Sbjct: 414 R---AEYNITITVTDLGTPMLITQLNMTVLIADVNDNAPAFTQTSYTLFVRENNSPALHI 470
Query: 128 XXXXXSDRDQPGPHSALHYAVLP--GPHSEYLGFE--NELEPIIVVKKPLDFETVNNFTI 183
+DRD G ++ + Y++LP PH N + + LD+E + F
Sbjct: 471 RSVSATDRDS-GTNAQVTYSLLPPQDPHLPLTSLVSINADNGHLFALRSLDYEALQGFQF 529
Query: 184 KLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTY------EHYTALLPDDAEEGTFLTTS 237
++ D GSP L S+ ++V VLDA+D +P Y T L+P AE G +T
Sbjct: 530 RVGASDHGSPALSSEALVRVVVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVT-- 587
Query: 238 PGPISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPSV-TIVLKA 295
+ A D D G NA L Y L V G+V T +L++E D + +V+
Sbjct: 588 --KVVAVDGDSGQNAWLSYQLLKATELGLFGVWAHNGEV-RTARLLSERDAAKHRLVVLV 644
Query: 296 TQVDNPDRYALATL 309
P R A ATL
Sbjct: 645 KDNGEPPRSATATL 658
Score = 78.2 bits (184), Expect = 1e-13
Identities = 105/447 (23%), Positives = 181/447 (40%), Gaps = 32/447 (7%)
Query: 4 GAVE--SFFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLL 60
GA E S+ + E+T S + L+ + G + +R+ +G + + + LL
Sbjct: 27 GAAEPRSYSVVEETEGSSFVTNLAKDLGLEQREFSRRGVRVVSRGNKLHLQLNQETADLL 86
Query: 61 --RALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVS 118
LDRE+ G + V +R + P ++V D+ND++P + V+VS
Sbjct: 87 LNEKLDREDLCGHTEPCV-LRF-QVLLESPFEFFQAELQVIDINDHSPVFLDKQMLVKVS 144
Query: 119 ETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLG---FENELEPIIVVKKPLDF 175
E+ D D G ++ +Y + P + L + P +V+ K LD
Sbjct: 145 ESSPPGTTFPLKNAEDLDV-GQNNIENYIISPNSYFRVLTRKRSDGRKYPELVLDKALDR 203
Query: 176 ETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLT 235
E + L D GSPP + + VLD +D P+F Y + +D+ G FL
Sbjct: 204 EEEAELRLTLTALDGGSPPRSGTAQVYIEVLDVNDNAPEFEQPFYRVQISEDSPVG-FLV 262
Query: 236 TSPGPISAADQDLGINAPLQYS---STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIV 292
+SA D D G+N + YS ++ + + +N TG++ KQL E
Sbjct: 263 VK---VSATDVDTGVNGEISYSLFQASEEIGKTFKINPLTGEIELKKQLDFE-------K 312
Query: 293 LKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTT 352
L++ +V+ R A + T +++ + E A P +V + L +
Sbjct: 313 LQSYEVNIEARDAGTFSGKCTVLIQVIDVNDHAPEVTMSAFTSPIPENA-PETV-VALFS 370
Query: 353 VPQNTEFRESPLQFYV-SDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTD---S 408
V + + D FL K A N ++ R LD E+ + Y + VTD
Sbjct: 371 VSDLDSGENGKISCSIQEDLPFLLKSA-ENFYTLLTERPLDRESRAEYNITITVTDLGTP 429
Query: 409 ISNDTASINISVEDVNEWEPRFRHPQY 435
+ ++ + + DVN+ P F Y
Sbjct: 430 MLITQLNMTVLIADVNDNAPAFTQTSY 456
>AF152506-1|AAD43767.1| 820|Homo sapiens protocadherin gamma A12
short form protein protein.
Length = 820
Score = 93.9 bits (223), Expect = 2e-18
Identities = 109/441 (24%), Positives = 180/441 (40%), Gaps = 30/441 (6%)
Query: 9 FFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAA--VGIVPGSKNLTLLRALDR 65
+ + E+ GS +G +S + G +L + +R+ +G + P S +L +DR
Sbjct: 33 YSVPEELEKGSRVGDISRDLGLEPRELAERGVRIIPRGRTQLFALNPRSGSLVTAGRIDR 92
Query: 66 EEK-IGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXX 124
EE +G +N+ D + V V V D+NDNAP + + +++SE
Sbjct: 93 EELCMGAIKCQLNLDI---LMEDKVKIYGVEVEVRDINDNAPYFRESELEIKISENAATE 149
Query: 125 XXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYL---GFENELEPIIVVKKPLDFETVNNF 181
D D G +S Y + P H + G + P +V+K+ LD E
Sbjct: 150 MRFPLPHAWDPDI-GKNSLQSYELSPNTHFSLIVQNGADGSKYPELVLKRALDREEKAAH 208
Query: 182 TIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPI 241
+ L D G P ++V VLDA+D P F Y A +P++ GT L +
Sbjct: 209 HLVLTASDGGDPVRTGTARIRVMVLDANDNAPAFAQPEYRASVPENLALGTQLLV----V 264
Query: 242 SAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELD--PSVTIVLKATQV 298
+A D D G+NA ++YS D K V D + T I ELD S ++ +
Sbjct: 265 NATDPDEGVNAEVRYSFRYVDDKAAQVFKLDCN--SGTISTIGELDHEESGFYQMEVQAM 322
Query: 299 DNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTE 358
DN A A + + +++V E + G+++ L Q++E
Sbjct: 323 DNAGYSARAKVLITVLDVNDNAP-----EVVLTSLASSVPENSPRGTLIALLNVNDQDSE 377
Query: 359 FRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTD----SISNDTA 414
+ F + F + + N ++ LD E +Y V TD +S +T
Sbjct: 378 ENGQVICFIQGNLPFKLEKSYGNYYSLVTDIVLDREQVPSYNITVTATDRGTPPLSTET- 436
Query: 415 SINISVEDVNEWEPRFRHPQY 435
I+++V D N+ P F Y
Sbjct: 437 HISLNVADTNDNPPVFPQASY 457
Score = 74.5 bits (175), Expect = 1e-12
Identities = 79/313 (25%), Positives = 123/313 (39%), Gaps = 22/313 (7%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLR--ALDREEK 68
+ E++P G++I L+VN SE+ G + +Q +L+ LDRE+
Sbjct: 356 VPENSPRGTLIALLNVNDQDSEENGQVICFIQGNLPFKLEKSYGNYYSLVTDIVLDREQV 415
Query: 69 IGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXX 128
PS + V R T S +S+ V D NDN P + A Y+ + E
Sbjct: 416 --PS-YNITVTATDRGTPPLSTETHISLNVADTNDNPPVFPQASYSAYIPENNPRGVSLV 472
Query: 129 XXXXSDRDQPG----PHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIK 184
D D +S + S Y+ ++ ++ D+E + +K
Sbjct: 473 SVTAHDPDCEENAQITYSLAENTIQGASLSSYVSINSDTG-VLYALSSFDYEQFRDLQVK 531
Query: 185 LRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFL---TTSPG-- 239
+ +D G PPL S+ +L + VLD +D P+ Y LP D G L + PG
Sbjct: 532 VMARDNGHPPLSSNVSLSLFVLDQNDNAPEILY----PALPTDGSTGVELAPRSAEPGYL 587
Query: 240 --PISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKAT 296
+ A D+D G NA L Y L V TG+V + L+ ++V+
Sbjct: 588 VTKVVAVDRDSGQNAWLSYRLLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQ 647
Query: 297 QVDNPDRYALATL 309
P A TL
Sbjct: 648 DHGQPPLSATVTL 660
Score = 63.3 bits (147), Expect = 4e-09
Identities = 51/190 (26%), Positives = 81/190 (42%), Gaps = 12/190 (6%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
V + V DVNDNAP+ A V E +D+D + + P
Sbjct: 333 VLITVLDVNDNAPEVVLTSLASSVPENSPRGTLIALLNVNDQDSEENGQVICFIQGNLPF 392
Query: 154 SEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNP 213
+ N +V LD E V ++ I + D+G+PPL ++T + + V D +D P
Sbjct: 393 KLEKSYGNYYS--LVTDIVLDREQVPSYNITVTATDRGTPPLSTETHISLNVADTNDNPP 450
Query: 214 KFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQ------LIV 267
F Y+A +P++ G L + ++A D D NA + YS + Q +
Sbjct: 451 VFPQASYSAYIPENNPRGVSLVS----VTAHDPDCEENAQITYSLAENTIQGASLSSYVS 506
Query: 268 VNKDTGQVAA 277
+N DTG + A
Sbjct: 507 INSDTGVLYA 516
Score = 38.3 bits (85), Expect = 0.12
Identities = 50/215 (23%), Positives = 86/215 (40%), Gaps = 13/215 (6%)
Query: 8 SFFISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQE---KGAAVG-IVPGSKNLTLLRAL 63
S +I E+ P G + +++ + E+ IT L E +GA++ V + + +L AL
Sbjct: 458 SAYIPENNPRGVSLVSVTAHDPDCEENAQITYSLAENTIQGASLSSYVSINSDTGVLYAL 517
Query: 64 DREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQ-------WEGAPYAVR 116
+ ++ V V S + +S+ V D NDNAP+ +G+
Sbjct: 518 SSFDYEQFRDLQVKVMARDNGHPPLSSNVSLSLFVLDQNDNAPEILYPALPTDGSTGVEL 577
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFE 176
+ DRD G ++ L Y +L + + LD +
Sbjct: 578 APRSAEPGYLVTKVVAVDRDS-GQNAWLSYRLLKASEPGLFSVGLHTGEVRTARALLDRD 636
Query: 177 TVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQ 211
+ ++ + VQD G PPL + TL V V D+ Q
Sbjct: 637 ALKQ-SLVVAVQDHGQPPLSATVTLTVAVADSIPQ 670
>AF152492-1|AAD43753.1| 798|Homo sapiens protocadherin beta 13
protein.
Length = 798
Score = 93.9 bits (223), Expect = 2e-18
Identities = 115/479 (24%), Positives = 187/479 (39%), Gaps = 33/479 (6%)
Query: 57 LTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVR 116
L L +ALDREE+ + + + + + S V + V DVNDNAP++E Y V+
Sbjct: 195 LVLDKALDREEE---AELRLTLTALDGGSPPRSGTAQVYIEVLDVNDNAPEFEQPFYRVQ 251
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPI---IVVKKPL 173
+SE +D D G + + Y++ SE +G ++ P+ I +KK L
Sbjct: 252 ISEDSPVGFLVVKVSATDVDT-GVNGEISYSLFQA--SEEIGKTFKINPLTGEIELKKQL 308
Query: 174 DFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTF 233
DFE + ++ + + +D G+ T+ + V+D +D P+ T +T+ +P++A E
Sbjct: 309 DFEKLQSYEVNIEARDAGT--FSGKCTVLIQVIDVNDHAPEVTMSAFTSPIPENAPE--- 363
Query: 234 LTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVL 293
T S +D D G N + S D L+ ++ + + L E I +
Sbjct: 364 --TVVALFSVSDLDSGENGKISCSIQEDLPFLLKSAENFYTLLTERPLDRESRAEYNITI 421
Query: 294 KATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPG----SVLLT 349
T + P + FTQ Y+ V E SP SV T
Sbjct: 422 TVTDLGTP-----MLITQLNMTVLIADVNDNAPAFTQTSYTLFVRENNSPALHIRSVSAT 476
Query: 350 LTTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTDS 408
N + S L +IN + G + RSLDYE + ++V +D
Sbjct: 477 DRDSGTNAQVTYSLLPPQDPHLPLTSLVSINADNGHLFALRSLDYEALQGFQFRVGASDH 536
Query: 409 IS---NDTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGDA 465
S + A + + V D N+ P +P VA DGD+
Sbjct: 537 GSPALSSEALVRVVVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVTKVVAVDGDS 596
Query: 466 GTLA-LS---LAGQHARMFYINASGDLFLREEAIGNLNSSSLHLVATAIDSGIPPRQTS 520
G A LS L +F + A + +++ LV D+G PPR +
Sbjct: 597 GQNAWLSYQLLKATELGLFGVWAHNGEVRTARLLSERDAAKHRLVVLVKDNGEPPRSAT 655
Score = 80.2 bits (189), Expect = 3e-14
Identities = 89/314 (28%), Positives = 138/314 (43%), Gaps = 27/314 (8%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNL-TLL--RALDREE 67
I E+ P +++ SV+ S + G I+ +QE ++ ++N TLL R LDRE
Sbjct: 357 IPENAP-ETVVALFSVSDLDSGENGKISCSIQED--LPFLLKSAENFYTLLTERPLDRES 413
Query: 68 KIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXX 127
+ + + + T + ++V + DVNDNAP + Y + V E
Sbjct: 414 R---AEYNITITVTDLGTPMLITQLNMTVLIADVNDNAPAFTQTSYTLFVRENNSPALHI 470
Query: 128 XXXXXSDRDQPGPHSALHYAVLP--GPHSEYLGFE--NELEPIIVVKKPLDFETVNNFTI 183
+DRD G ++ + Y++LP PH N + + LD+E + F
Sbjct: 471 RSVSATDRDS-GTNAQVTYSLLPPQDPHLPLTSLVSINADNGHLFALRSLDYEALQGFQF 529
Query: 184 KLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTY------EHYTALLPDDAEEGTFLTTS 237
++ D GSP L S+ ++V VLDA+D +P Y T L+P AE G +T
Sbjct: 530 RVGASDHGSPALSSEALVRVVVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVT-- 587
Query: 238 PGPISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPSV-TIVLKA 295
+ A D D G NA L Y L V G+V T +L++E D + +V+
Sbjct: 588 --KVVAVDGDSGQNAWLSYQLLKATELGLFGVWAHNGEV-RTARLLSERDAAKHRLVVLV 644
Query: 296 TQVDNPDRYALATL 309
P R A ATL
Sbjct: 645 KDNGEPPRSATATL 658
Score = 78.2 bits (184), Expect = 1e-13
Identities = 105/447 (23%), Positives = 181/447 (40%), Gaps = 32/447 (7%)
Query: 4 GAVE--SFFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLL 60
GA E S+ + E+T S + L+ + G + +R+ +G + + + LL
Sbjct: 27 GAAEPRSYSVVEETEGSSFVTNLAKDLGLEQREFSRRGVRVVSRGNKLHLQLNQETADLL 86
Query: 61 --RALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVS 118
LDRE+ G + V +R + P ++V D+ND++P + V+VS
Sbjct: 87 LNEKLDREDLCGHTEPCV-LRF-QVLLESPFEFFQAELQVIDINDHSPVFLDKQMLVKVS 144
Query: 119 ETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLG---FENELEPIIVVKKPLDF 175
E+ D D G ++ +Y + P + L + P +V+ K LD
Sbjct: 145 ESSPPGTTFPLKNAEDLDV-GQNNIENYIISPNSYFRVLTRKRSDGRKYPELVLDKALDR 203
Query: 176 ETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLT 235
E + L D GSPP + + VLD +D P+F Y + +D+ G FL
Sbjct: 204 EEEAELRLTLTALDGGSPPRSGTAQVYIEVLDVNDNAPEFEQPFYRVQISEDSPVG-FLV 262
Query: 236 TSPGPISAADQDLGINAPLQYS---STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIV 292
+SA D D G+N + YS ++ + + +N TG++ KQL E
Sbjct: 263 VK---VSATDVDTGVNGEISYSLFQASEEIGKTFKINPLTGEIELKKQLDFE-------K 312
Query: 293 LKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTT 352
L++ +V+ R A + T +++ + E A P +V + L +
Sbjct: 313 LQSYEVNIEARDAGTFSGKCTVLIQVIDVNDHAPEVTMSAFTSPIPENA-PETV-VALFS 370
Query: 353 VPQNTEFRESPLQFYV-SDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTD---S 408
V + + D FL K A N ++ R LD E+ + Y + VTD
Sbjct: 371 VSDLDSGENGKISCSIQEDLPFLLKSA-ENFYTLLTERPLDRESRAEYNITITVTDLGTP 429
Query: 409 ISNDTASINISVEDVNEWEPRFRHPQY 435
+ ++ + + DVN+ P F Y
Sbjct: 430 MLITQLNMTVLIADVNDNAPAFTQTSY 456
>AF152321-1|AAD43715.1| 932|Homo sapiens protocadherin gamma A12
protein.
Length = 932
Score = 93.9 bits (223), Expect = 2e-18
Identities = 109/441 (24%), Positives = 180/441 (40%), Gaps = 30/441 (6%)
Query: 9 FFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAA--VGIVPGSKNLTLLRALDR 65
+ + E+ GS +G +S + G +L + +R+ +G + P S +L +DR
Sbjct: 33 YSVPEELEKGSRVGDISRDLGLEPRELAERGVRIIPRGRTQLFALNPRSGSLVTAGRIDR 92
Query: 66 EEK-IGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXX 124
EE +G +N+ D + V V V D+NDNAP + + +++SE
Sbjct: 93 EELCMGAIKCQLNLDI---LMEDKVKIYGVEVEVRDINDNAPYFRESELEIKISENAATE 149
Query: 125 XXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYL---GFENELEPIIVVKKPLDFETVNNF 181
D D G +S Y + P H + G + P +V+K+ LD E
Sbjct: 150 MRFPLPHAWDPDI-GKNSLQSYELSPNTHFSLIVQNGADGSKYPELVLKRALDREEKAAH 208
Query: 182 TIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPI 241
+ L D G P ++V VLDA+D P F Y A +P++ GT L +
Sbjct: 209 HLVLTASDGGDPVRTGTARIRVMVLDANDNAPAFAQPEYRASVPENLALGTQLLV----V 264
Query: 242 SAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELD--PSVTIVLKATQV 298
+A D D G+NA ++YS D K V D + T I ELD S ++ +
Sbjct: 265 NATDPDEGVNAEVRYSFRYVDDKAAQVFKLDCN--SGTISTIGELDHEESGFYQMEVQAM 322
Query: 299 DNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTE 358
DN A A + + +++V E + G+++ L Q++E
Sbjct: 323 DNAGYSARAKVLITVLDVNDNAP-----EVVLTSLASSVPENSPRGTLIALLNVNDQDSE 377
Query: 359 FRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTD----SISNDTA 414
+ F + F + + N ++ LD E +Y V TD +S +T
Sbjct: 378 ENGQVICFIQGNLPFKLEKSYGNYYSLVTDIVLDREQVPSYNITVTATDRGTPPLSTET- 436
Query: 415 SINISVEDVNEWEPRFRHPQY 435
I+++V D N+ P F Y
Sbjct: 437 HISLNVADTNDNPPVFPQASY 457
Score = 74.5 bits (175), Expect = 1e-12
Identities = 79/313 (25%), Positives = 123/313 (39%), Gaps = 22/313 (7%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLR--ALDREEK 68
+ E++P G++I L+VN SE+ G + +Q +L+ LDRE+
Sbjct: 356 VPENSPRGTLIALLNVNDQDSEENGQVICFIQGNLPFKLEKSYGNYYSLVTDIVLDREQV 415
Query: 69 IGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXX 128
PS + V R T S +S+ V D NDN P + A Y+ + E
Sbjct: 416 --PS-YNITVTATDRGTPPLSTETHISLNVADTNDNPPVFPQASYSAYIPENNPRGVSLV 472
Query: 129 XXXXSDRDQPG----PHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIK 184
D D +S + S Y+ ++ ++ D+E + +K
Sbjct: 473 SVTAHDPDCEENAQITYSLAENTIQGASLSSYVSINSDTG-VLYALSSFDYEQFRDLQVK 531
Query: 185 LRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFL---TTSPG-- 239
+ +D G PPL S+ +L + VLD +D P+ Y LP D G L + PG
Sbjct: 532 VMARDNGHPPLSSNVSLSLFVLDQNDNAPEILY----PALPTDGSTGVELAPRSAEPGYL 587
Query: 240 --PISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKAT 296
+ A D+D G NA L Y L V TG+V + L+ ++V+
Sbjct: 588 VTKVVAVDRDSGQNAWLSYRLLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQ 647
Query: 297 QVDNPDRYALATL 309
P A TL
Sbjct: 648 DHGQPPLSATVTL 660
Score = 63.3 bits (147), Expect = 4e-09
Identities = 51/190 (26%), Positives = 81/190 (42%), Gaps = 12/190 (6%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
V + V DVNDNAP+ A V E +D+D + + P
Sbjct: 333 VLITVLDVNDNAPEVVLTSLASSVPENSPRGTLIALLNVNDQDSEENGQVICFIQGNLPF 392
Query: 154 SEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNP 213
+ N +V LD E V ++ I + D+G+PPL ++T + + V D +D P
Sbjct: 393 KLEKSYGNYYS--LVTDIVLDREQVPSYNITVTATDRGTPPLSTETHISLNVADTNDNPP 450
Query: 214 KFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQ------LIV 267
F Y+A +P++ G L + ++A D D NA + YS + Q +
Sbjct: 451 VFPQASYSAYIPENNPRGVSLVS----VTAHDPDCEENAQITYSLAENTIQGASLSSYVS 506
Query: 268 VNKDTGQVAA 277
+N DTG + A
Sbjct: 507 INSDTGVLYA 516
Score = 38.3 bits (85), Expect = 0.12
Identities = 50/215 (23%), Positives = 86/215 (40%), Gaps = 13/215 (6%)
Query: 8 SFFISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQE---KGAAVG-IVPGSKNLTLLRAL 63
S +I E+ P G + +++ + E+ IT L E +GA++ V + + +L AL
Sbjct: 458 SAYIPENNPRGVSLVSVTAHDPDCEENAQITYSLAENTIQGASLSSYVSINSDTGVLYAL 517
Query: 64 DREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQ-------WEGAPYAVR 116
+ ++ V V S + +S+ V D NDNAP+ +G+
Sbjct: 518 SSFDYEQFRDLQVKVMARDNGHPPLSSNVSLSLFVLDQNDNAPEILYPALPTDGSTGVEL 577
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFE 176
+ DRD G ++ L Y +L + + LD +
Sbjct: 578 APRSAEPGYLVTKVVAVDRDS-GQNAWLSYRLLKASEPGLFSVGLHTGEVRTARALLDRD 636
Query: 177 TVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQ 211
+ ++ + VQD G PPL + TL V V D+ Q
Sbjct: 637 ALKQ-SLVVAVQDHGQPPLSATVTLTVAVADSIPQ 670
>AB011160-1|BAA25514.2| 938|Homo sapiens KIAA0588 protein protein.
Length = 938
Score = 93.9 bits (223), Expect = 2e-18
Identities = 109/441 (24%), Positives = 180/441 (40%), Gaps = 30/441 (6%)
Query: 9 FFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAA--VGIVPGSKNLTLLRALDR 65
+ + E+ GS +G +S + G +L + +R+ +G + P S +L +DR
Sbjct: 39 YSVPEELEKGSRVGDISRDLGLEPRELAERGVRIIPRGRTQLFALNPRSGSLVTAGRIDR 98
Query: 66 EEK-IGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXX 124
EE +G +N+ D + V V V D+NDNAP + + +++SE
Sbjct: 99 EELCMGAIKCQLNLDI---LMEDKVKIYGVEVEVRDINDNAPYFRESELEIKISENAATE 155
Query: 125 XXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYL---GFENELEPIIVVKKPLDFETVNNF 181
D D G +S Y + P H + G + P +V+K+ LD E
Sbjct: 156 MRFPLPHAWDPDI-GKNSLQSYELSPNTHFSLIVQNGADGSKYPELVLKRALDREEKAAH 214
Query: 182 TIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPI 241
+ L D G P ++V VLDA+D P F Y A +P++ GT L +
Sbjct: 215 HLVLTASDGGDPVRTGTARIRVMVLDANDNAPAFAQPEYRASVPENLALGTQLLV----V 270
Query: 242 SAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELD--PSVTIVLKATQV 298
+A D D G+NA ++YS D K V D + T I ELD S ++ +
Sbjct: 271 NATDPDEGVNAEVRYSFRYVDDKAAQVFKLDCN--SGTISTIGELDHEESGFYQMEVQAM 328
Query: 299 DNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTE 358
DN A A + + +++V E + G+++ L Q++E
Sbjct: 329 DNAGYSARAKVLITVLDVNDNAP-----EVVLTSLASSVPENSPRGTLIALLNVNDQDSE 383
Query: 359 FRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTD----SISNDTA 414
+ F + F + + N ++ LD E +Y V TD +S +T
Sbjct: 384 ENGQVICFIQGNLPFKLEKSYGNYYSLVTDIVLDREQVPSYNITVTATDRGTPPLSTET- 442
Query: 415 SINISVEDVNEWEPRFRHPQY 435
I+++V D N+ P F Y
Sbjct: 443 HISLNVADTNDNPPVFPQASY 463
Score = 74.5 bits (175), Expect = 1e-12
Identities = 79/313 (25%), Positives = 123/313 (39%), Gaps = 22/313 (7%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLR--ALDREEK 68
+ E++P G++I L+VN SE+ G + +Q +L+ LDRE+
Sbjct: 362 VPENSPRGTLIALLNVNDQDSEENGQVICFIQGNLPFKLEKSYGNYYSLVTDIVLDREQV 421
Query: 69 IGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXX 128
PS + V R T S +S+ V D NDN P + A Y+ + E
Sbjct: 422 --PS-YNITVTATDRGTPPLSTETHISLNVADTNDNPPVFPQASYSAYIPENNPRGVSLV 478
Query: 129 XXXXSDRDQPG----PHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIK 184
D D +S + S Y+ ++ ++ D+E + +K
Sbjct: 479 SVTAHDPDCEENAQITYSLAENTIQGASLSSYVSINSDTG-VLYALSSFDYEQFRDLQVK 537
Query: 185 LRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFL---TTSPG-- 239
+ +D G PPL S+ +L + VLD +D P+ Y LP D G L + PG
Sbjct: 538 VMARDNGHPPLSSNVSLSLFVLDQNDNAPEILY----PALPTDGSTGVELAPRSAEPGYL 593
Query: 240 --PISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKAT 296
+ A D+D G NA L Y L V TG+V + L+ ++V+
Sbjct: 594 VTKVVAVDRDSGQNAWLSYRLLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQ 653
Query: 297 QVDNPDRYALATL 309
P A TL
Sbjct: 654 DHGQPPLSATVTL 666
Score = 63.3 bits (147), Expect = 4e-09
Identities = 51/190 (26%), Positives = 81/190 (42%), Gaps = 12/190 (6%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
V + V DVNDNAP+ A V E +D+D + + P
Sbjct: 339 VLITVLDVNDNAPEVVLTSLASSVPENSPRGTLIALLNVNDQDSEENGQVICFIQGNLPF 398
Query: 154 SEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNP 213
+ N +V LD E V ++ I + D+G+PPL ++T + + V D +D P
Sbjct: 399 KLEKSYGNYYS--LVTDIVLDREQVPSYNITVTATDRGTPPLSTETHISLNVADTNDNPP 456
Query: 214 KFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQ------LIV 267
F Y+A +P++ G L + ++A D D NA + YS + Q +
Sbjct: 457 VFPQASYSAYIPENNPRGVSLVS----VTAHDPDCEENAQITYSLAENTIQGASLSSYVS 512
Query: 268 VNKDTGQVAA 277
+N DTG + A
Sbjct: 513 INSDTGVLYA 522
Score = 38.3 bits (85), Expect = 0.12
Identities = 50/215 (23%), Positives = 86/215 (40%), Gaps = 13/215 (6%)
Query: 8 SFFISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQE---KGAAVG-IVPGSKNLTLLRAL 63
S +I E+ P G + +++ + E+ IT L E +GA++ V + + +L AL
Sbjct: 464 SAYIPENNPRGVSLVSVTAHDPDCEENAQITYSLAENTIQGASLSSYVSINSDTGVLYAL 523
Query: 64 DREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQ-------WEGAPYAVR 116
+ ++ V V S + +S+ V D NDNAP+ +G+
Sbjct: 524 SSFDYEQFRDLQVKVMARDNGHPPLSSNVSLSLFVLDQNDNAPEILYPALPTDGSTGVEL 583
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFE 176
+ DRD G ++ L Y +L + + LD +
Sbjct: 584 APRSAEPGYLVTKVVAVDRDS-GQNAWLSYRLLKASEPGLFSVGLHTGEVRTARALLDRD 642
Query: 177 TVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQ 211
+ ++ + VQD G PPL + TL V V D+ Q
Sbjct: 643 ALKQ-SLVVAVQDHGQPPLSATVTLTVAVADSIPQ 676
>AF152478-1|AAD43739.1| 807|Homo sapiens protocadherin alpha 13
short form protein protein.
Length = 807
Score = 93.5 bits (222), Expect = 3e-18
Identities = 97/387 (25%), Positives = 159/387 (41%), Gaps = 30/387 (7%)
Query: 63 LDREEKIGPS---NVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSE 119
+DREE G S ++++ V DR P V V V+V D+NDN P + + + ++E
Sbjct: 90 IDREELCGRSAECSIHLEVIVDR-----PLQVFHVEVKVRDINDNPPIFPESKKRIIIAE 144
Query: 120 TXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPI----IVVKKPLDF 175
+ SD D G +SAL Y + P + L +N LE + +V++K LD
Sbjct: 145 SRPPETRFPLDGASDADI-GVNSALTYRLDPNDYFT-LDAQNSLEQMSSLSLVLRKTLDR 202
Query: 176 ETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLT 235
E + ++ L D G P L L +T+LD +D P+F Y + ++A GT +
Sbjct: 203 EEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAPEFYQSVYKVTVLENAFNGTLVI 262
Query: 236 TSPGPISAADQDLGINAPLQYSSTGDHKQLIV----VNKDTGQVAATKQLIAELDPSVTI 291
++A D D G N + YS +V +N + G++ +L E I
Sbjct: 263 ----KLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNGEIRTKGKLDFEEKKLYEI 318
Query: 292 VLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLT 351
++A N TL + T S + E P +++ ++
Sbjct: 319 SVEAVDKGNIPMAGHCTLLVEVLDVNDNAP-----EVTITSLSLPIREDTQPSAIIALIS 373
Query: 352 TVPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSISN 411
+++ F N ++L +LD E+ S Y V D S
Sbjct: 374 VSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTARDGGSP 433
Query: 412 D---TASINISVEDVNEWEPRFRHPQY 435
TAS+++ V DVN+ P F P+Y
Sbjct: 434 SLWATASVSVGVADVNDNAPAFAQPEY 460
Score = 75.8 bits (178), Expect = 6e-13
Identities = 92/393 (23%), Positives = 157/393 (39%), Gaps = 28/393 (7%)
Query: 54 SKNLTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPY 113
S +L L + LDREE S + + T + + + + DVNDNAP++ + Y
Sbjct: 191 SLSLVLRKTLDREEIQEHSLLLTASDGGKPELTG---TVQLLITILDVNDNAPEFYQSVY 247
Query: 114 AVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPG--PHSEYLGFENELEPIIVVKK 171
V V E +D D G + + Y+ P Y N I K
Sbjct: 248 KVTVLENAFNGTLVIKLNATDPDD-GTNGDIVYSFRRPVWPAVVYAFTINPNNGEIRTKG 306
Query: 172 PLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEG 231
LDFE + I + D+G+ P+ TL V VLD +D P+ T + + +D +
Sbjct: 307 KLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIREDTQPS 366
Query: 232 TFLTTSPGPISAADQDLGINAPLQYSSTGDHK-QLIVVNKDTGQVAATKQLIAELDPSVT 290
+ IS +D+D G N + + T +L+ K+ + L E +
Sbjct: 367 AIIAL----ISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYE 422
Query: 291 IVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTL 350
+V+ A +P +A A++ F Q +Y+ V E PG + T+
Sbjct: 423 LVVTARDGGSPSLWATASVSVGVADVNDNAPA-----FAQPEYTVFVKENNPPGCHIFTV 477
Query: 351 TTVPQNTEFRESPLQFY------VSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQV 403
+ Q+ + +E+ L Y V +R+ +++ +G+V + LD+E +QV
Sbjct: 478 SA--QDADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQV 535
Query: 404 MVTDS---ISNDTASINISVEDVNEWEPRFRHP 433
DS ++ + V D N+ P P
Sbjct: 536 SARDSGVPPLGSNVTLQVFVLDENDNAPALLTP 568
Score = 64.1 bits (149), Expect = 2e-09
Identities = 67/212 (31%), Positives = 87/212 (41%), Gaps = 16/212 (7%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKN---LTLLRALDREE 67
I EDT +II +SV+ S G +T L +V KN L L ALDRE
Sbjct: 359 IREDTQPSAIIALISVSDRDSGSNGQVTCTLTPH-VPFKLVSTYKNYYSLVLDSALDRES 417
Query: 68 KIGPSNVYVNVRCDRRRTTDPSF--VIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXX 125
+ + V R PS VSV V DVNDNAP + Y V V E
Sbjct: 418 -VSAYELVVTARDGG----SPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGC 472
Query: 126 XXXXXXXSDRDQPG----PHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNF 181
D D +S + V S Y+ E + ++ PLD E +
Sbjct: 473 HIFTVSAQDADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQ-PLDHEELELL 531
Query: 182 TIKLRVQDQGSPPLYSDTTLQVTVLDADDQNP 213
++ +D G PPL S+ TLQV VLD +D P
Sbjct: 532 QFQVSARDSGVPPLGSNVTLQVFVLDENDNAP 563
>AF152309-1|AAD43703.1| 950|Homo sapiens protocadherin alpha 13
protein.
Length = 950
Score = 93.5 bits (222), Expect = 3e-18
Identities = 97/387 (25%), Positives = 159/387 (41%), Gaps = 30/387 (7%)
Query: 63 LDREEKIGPS---NVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSE 119
+DREE G S ++++ V DR P V V V+V D+NDN P + + + ++E
Sbjct: 90 IDREELCGRSAECSIHLEVIVDR-----PLQVFHVEVKVRDINDNPPIFPESKKRIIIAE 144
Query: 120 TXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPI----IVVKKPLDF 175
+ SD D G +SAL Y + P + L +N LE + +V++K LD
Sbjct: 145 SRPPETRFPLDGASDADI-GVNSALTYRLDPNDYFT-LDAQNSLEQMSSLSLVLRKTLDR 202
Query: 176 ETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLT 235
E + ++ L D G P L L +T+LD +D P+F Y + ++A GT +
Sbjct: 203 EEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAPEFYQSVYKVTVLENAFNGTLVI 262
Query: 236 TSPGPISAADQDLGINAPLQYSSTGDHKQLIV----VNKDTGQVAATKQLIAELDPSVTI 291
++A D D G N + YS +V +N + G++ +L E I
Sbjct: 263 ----KLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNGEIRTKGKLDFEEKKLYEI 318
Query: 292 VLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLT 351
++A N TL + T S + E P +++ ++
Sbjct: 319 SVEAVDKGNIPMAGHCTLLVEVLDVNDNAP-----EVTITSLSLPIREDTQPSAIIALIS 373
Query: 352 TVPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSISN 411
+++ F N ++L +LD E+ S Y V D S
Sbjct: 374 VSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTARDGGSP 433
Query: 412 D---TASINISVEDVNEWEPRFRHPQY 435
TAS+++ V DVN+ P F P+Y
Sbjct: 434 SLWATASVSVGVADVNDNAPAFAQPEY 460
Score = 75.8 bits (178), Expect = 6e-13
Identities = 92/393 (23%), Positives = 157/393 (39%), Gaps = 28/393 (7%)
Query: 54 SKNLTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPY 113
S +L L + LDREE S + + T + + + + DVNDNAP++ + Y
Sbjct: 191 SLSLVLRKTLDREEIQEHSLLLTASDGGKPELTG---TVQLLITILDVNDNAPEFYQSVY 247
Query: 114 AVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPG--PHSEYLGFENELEPIIVVKK 171
V V E +D D G + + Y+ P Y N I K
Sbjct: 248 KVTVLENAFNGTLVIKLNATDPDD-GTNGDIVYSFRRPVWPAVVYAFTINPNNGEIRTKG 306
Query: 172 PLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEG 231
LDFE + I + D+G+ P+ TL V VLD +D P+ T + + +D +
Sbjct: 307 KLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIREDTQPS 366
Query: 232 TFLTTSPGPISAADQDLGINAPLQYSSTGDHK-QLIVVNKDTGQVAATKQLIAELDPSVT 290
+ IS +D+D G N + + T +L+ K+ + L E +
Sbjct: 367 AIIAL----ISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYE 422
Query: 291 IVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTL 350
+V+ A +P +A A++ F Q +Y+ V E PG + T+
Sbjct: 423 LVVTARDGGSPSLWATASVSVGVADVNDNAPA-----FAQPEYTVFVKENNPPGCHIFTV 477
Query: 351 TTVPQNTEFRESPLQFY------VSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQV 403
+ Q+ + +E+ L Y V +R+ +++ +G+V + LD+E +QV
Sbjct: 478 SA--QDADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQV 535
Query: 404 MVTDS---ISNDTASINISVEDVNEWEPRFRHP 433
DS ++ + V D N+ P P
Sbjct: 536 SARDSGVPPLGSNVTLQVFVLDENDNAPALLTP 568
Score = 64.1 bits (149), Expect = 2e-09
Identities = 67/212 (31%), Positives = 87/212 (41%), Gaps = 16/212 (7%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKN---LTLLRALDREE 67
I EDT +II +SV+ S G +T L +V KN L L ALDRE
Sbjct: 359 IREDTQPSAIIALISVSDRDSGSNGQVTCTLTPH-VPFKLVSTYKNYYSLVLDSALDRES 417
Query: 68 KIGPSNVYVNVRCDRRRTTDPSF--VIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXX 125
+ + V R PS VSV V DVNDNAP + Y V V E
Sbjct: 418 -VSAYELVVTARDGG----SPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGC 472
Query: 126 XXXXXXXSDRDQPG----PHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNF 181
D D +S + V S Y+ E + ++ PLD E +
Sbjct: 473 HIFTVSAQDADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQ-PLDHEELELL 531
Query: 182 TIKLRVQDQGSPPLYSDTTLQVTVLDADDQNP 213
++ +D G PPL S+ TLQV VLD +D P
Sbjct: 532 QFQVSARDSGVPPLGSNVTLQVFVLDENDNAP 563
>AC005609-1|AAC34314.1| 807|Homo sapiens KIAA0345-like 1 protein.
Length = 807
Score = 93.5 bits (222), Expect = 3e-18
Identities = 97/387 (25%), Positives = 159/387 (41%), Gaps = 30/387 (7%)
Query: 63 LDREEKIGPS---NVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSE 119
+DREE G S ++++ V DR P V V V+V D+NDN P + + + ++E
Sbjct: 90 IDREELCGRSAECSIHLEVIVDR-----PLQVFHVEVKVRDINDNPPIFPESKKRIIIAE 144
Query: 120 TXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPI----IVVKKPLDF 175
+ SD D G +SAL Y + P + L +N LE + +V++K LD
Sbjct: 145 SRPPETRFPLDGASDADI-GVNSALTYRLDPNDYFT-LDAQNSLEQMSSLSLVLRKTLDR 202
Query: 176 ETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLT 235
E + ++ L D G P L L +T+LD +D P+F Y + ++A GT +
Sbjct: 203 EEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAPEFYQSVYKVTVLENAFNGTLVI 262
Query: 236 TSPGPISAADQDLGINAPLQYSSTGDHKQLIV----VNKDTGQVAATKQLIAELDPSVTI 291
++A D D G N + YS +V +N + G++ +L E I
Sbjct: 263 ----KLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNGEIRTKGKLDFEEKKLYEI 318
Query: 292 VLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLT 351
++A N TL + T S + E P +++ ++
Sbjct: 319 SVEAVDKGNIPMAGHCTLLVEVLDVNDNAP-----EVTITSLSLPIREDTQPSAIIALIS 373
Query: 352 TVPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSISN 411
+++ F N ++L +LD E+ S Y V D S
Sbjct: 374 VSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTARDGGSP 433
Query: 412 D---TASINISVEDVNEWEPRFRHPQY 435
TAS+++ V DVN+ P F P+Y
Sbjct: 434 SLWATASVSVGVADVNDNAPAFAQPEY 460
Score = 75.8 bits (178), Expect = 6e-13
Identities = 92/393 (23%), Positives = 157/393 (39%), Gaps = 28/393 (7%)
Query: 54 SKNLTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPY 113
S +L L + LDREE S + + T + + + + DVNDNAP++ + Y
Sbjct: 191 SLSLVLRKTLDREEIQEHSLLLTASDGGKPELTG---TVQLLITILDVNDNAPEFYQSVY 247
Query: 114 AVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPG--PHSEYLGFENELEPIIVVKK 171
V V E +D D G + + Y+ P Y N I K
Sbjct: 248 KVTVLENAFNGTLVIKLNATDPDD-GTNGDIVYSFRRPVWPAVVYAFTINPNNGEIRTKG 306
Query: 172 PLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEG 231
LDFE + I + D+G+ P+ TL V VLD +D P+ T + + +D +
Sbjct: 307 KLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIREDTQPS 366
Query: 232 TFLTTSPGPISAADQDLGINAPLQYSSTGDHK-QLIVVNKDTGQVAATKQLIAELDPSVT 290
+ IS +D+D G N + + T +L+ K+ + L E +
Sbjct: 367 AIIAL----ISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYE 422
Query: 291 IVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTL 350
+V+ A +P +A A++ F Q +Y+ V E PG + T+
Sbjct: 423 LVVTARDGGSPSLWATASVSVGVADVNDNAPA-----FAQPEYTVFVKENNPPGCHIFTV 477
Query: 351 TTVPQNTEFRESPLQFY------VSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQV 403
+ Q+ + +E+ L Y V +R+ +++ +G+V + LD+E +QV
Sbjct: 478 SA--QDADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQV 535
Query: 404 MVTDS---ISNDTASINISVEDVNEWEPRFRHP 433
DS ++ + V D N+ P P
Sbjct: 536 SARDSGVPPLGSNVTLQVFVLDENDNAPALLTP 568
Score = 64.1 bits (149), Expect = 2e-09
Identities = 67/212 (31%), Positives = 87/212 (41%), Gaps = 16/212 (7%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKN---LTLLRALDREE 67
I EDT +II +SV+ S G +T L +V KN L L ALDRE
Sbjct: 359 IREDTQPSAIIALISVSDRDSGSNGQVTCTLTPH-VPFKLVSTYKNYYSLVLDSALDRES 417
Query: 68 KIGPSNVYVNVRCDRRRTTDPSF--VIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXX 125
+ + V R PS VSV V DVNDNAP + Y V V E
Sbjct: 418 -VSAYELVVTARDGG----SPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGC 472
Query: 126 XXXXXXXSDRDQPG----PHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNF 181
D D +S + V S Y+ E + ++ PLD E +
Sbjct: 473 HIFTVSAQDADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQ-PLDHEELELL 531
Query: 182 TIKLRVQDQGSPPLYSDTTLQVTVLDADDQNP 213
++ +D G PPL S+ TLQV VLD +D P
Sbjct: 532 QFQVSARDSGVPPLGSNVTLQVFVLDENDNAP 563
>AB208924-1|BAD92161.1| 921|Homo sapiens protocadherin alpha 13
isoform 1 precursor variant protein.
Length = 921
Score = 93.5 bits (222), Expect = 3e-18
Identities = 97/387 (25%), Positives = 159/387 (41%), Gaps = 30/387 (7%)
Query: 63 LDREEKIGPS---NVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSE 119
+DREE G S ++++ V DR P V V V+V D+NDN P + + + ++E
Sbjct: 107 IDREELCGRSAECSIHLEVIVDR-----PLQVFHVEVKVRDINDNPPIFPESKKRIIIAE 161
Query: 120 TXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPI----IVVKKPLDF 175
+ SD D G +SAL Y + P + L +N LE + +V++K LD
Sbjct: 162 SRPPETRFPLDGASDADI-GVNSALTYRLDPNDYFT-LDAQNSLEQMSSLSLVLRKTLDR 219
Query: 176 ETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLT 235
E + ++ L D G P L L +T+LD +D P+F Y + ++A GT +
Sbjct: 220 EEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAPEFYQSVYKVTVLENAFNGTLVI 279
Query: 236 TSPGPISAADQDLGINAPLQYSSTGDHKQLIV----VNKDTGQVAATKQLIAELDPSVTI 291
++A D D G N + YS +V +N + G++ +L E I
Sbjct: 280 ----KLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNGEIRTKGKLDFEEKKLYEI 335
Query: 292 VLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLT 351
++A N TL + T S + E P +++ ++
Sbjct: 336 SVEAVDKGNIPMAGHCTLLVEVLDVNDNAP-----EVTITSLSLPIREDTQPSAIIALIS 390
Query: 352 TVPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSISN 411
+++ F N ++L +LD E+ S Y V D S
Sbjct: 391 VSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTARDGGSP 450
Query: 412 D---TASINISVEDVNEWEPRFRHPQY 435
TAS+++ V DVN+ P F P+Y
Sbjct: 451 SLWATASVSVGVADVNDNAPAFAQPEY 477
Score = 75.8 bits (178), Expect = 6e-13
Identities = 92/393 (23%), Positives = 157/393 (39%), Gaps = 28/393 (7%)
Query: 54 SKNLTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPY 113
S +L L + LDREE S + + T + + + + DVNDNAP++ + Y
Sbjct: 208 SLSLVLRKTLDREEIQEHSLLLTASDGGKPELTG---TVQLLITILDVNDNAPEFYQSVY 264
Query: 114 AVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPG--PHSEYLGFENELEPIIVVKK 171
V V E +D D G + + Y+ P Y N I K
Sbjct: 265 KVTVLENAFNGTLVIKLNATDPDD-GTNGDIVYSFRRPVWPAVVYAFTINPNNGEIRTKG 323
Query: 172 PLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEG 231
LDFE + I + D+G+ P+ TL V VLD +D P+ T + + +D +
Sbjct: 324 KLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIREDTQPS 383
Query: 232 TFLTTSPGPISAADQDLGINAPLQYSSTGDHK-QLIVVNKDTGQVAATKQLIAELDPSVT 290
+ IS +D+D G N + + T +L+ K+ + L E +
Sbjct: 384 AIIAL----ISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYE 439
Query: 291 IVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTL 350
+V+ A +P +A A++ F Q +Y+ V E PG + T+
Sbjct: 440 LVVTARDGGSPSLWATASVSVGVADVNDNAPA-----FAQPEYTVFVKENNPPGCHIFTV 494
Query: 351 TTVPQNTEFRESPLQFY------VSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQV 403
+ Q+ + +E+ L Y V +R+ +++ +G+V + LD+E +QV
Sbjct: 495 SA--QDADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQV 552
Query: 404 MVTDS---ISNDTASINISVEDVNEWEPRFRHP 433
DS ++ + V D N+ P P
Sbjct: 553 SARDSGVPPLGSNVTLQVFVLDENDNAPALLTP 585
Score = 64.1 bits (149), Expect = 2e-09
Identities = 67/212 (31%), Positives = 87/212 (41%), Gaps = 16/212 (7%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKN---LTLLRALDREE 67
I EDT +II +SV+ S G +T L +V KN L L ALDRE
Sbjct: 376 IREDTQPSAIIALISVSDRDSGSNGQVTCTLTPH-VPFKLVSTYKNYYSLVLDSALDRES 434
Query: 68 KIGPSNVYVNVRCDRRRTTDPSF--VIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXX 125
+ + V R PS VSV V DVNDNAP + Y V V E
Sbjct: 435 -VSAYELVVTARDGG----SPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGC 489
Query: 126 XXXXXXXSDRDQPG----PHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNF 181
D D +S + V S Y+ E + ++ PLD E +
Sbjct: 490 HIFTVSAQDADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQ-PLDHEELELL 548
Query: 182 TIKLRVQDQGSPPLYSDTTLQVTVLDADDQNP 213
++ +D G PPL S+ TLQV VLD +D P
Sbjct: 549 QFQVSARDSGVPPLGSNVTLQVFVLDENDNAP 580
>BC104804-1|AAI04805.1| 950|Homo sapiens protocadherin alpha 9
protein.
Length = 950
Score = 93.1 bits (221), Expect = 4e-18
Identities = 108/439 (24%), Positives = 177/439 (40%), Gaps = 23/439 (5%)
Query: 9 FFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAAVGIVPGSKN--LTLLRALDR 65
+ + E+ G+ +G ++ + G +L +L KG + +N L + +DR
Sbjct: 33 YSVPEEAEHGTFVGRIAQDLGLELAELVPRLFQLDSKGRGDLLEVNLQNGILFVNSRIDR 92
Query: 66 EEKIGPS---NVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXX 122
EE G S ++++ V DR P V V V V D+NDN P + + ++E+
Sbjct: 93 EELCGRSAECSIHLEVIVDR-----PLQVFHVDVEVKDINDNPPVFPATQKNLFIAESRP 147
Query: 123 XXXXXXXXXXSDRDQPGPHSALHYAVLPGPHS--EYLGFENELEPI-IVVKKPLDFETVN 179
SD D G ++ L Y + P + + +++P+ +V++K LD E
Sbjct: 148 LDSRFPLEGASDADI-GENALLTYRLSPNEYFFLDVPTSNQQVKPLGLVLRKLLDREETP 206
Query: 180 NFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPG 239
+ L D G P L L +TVLD +D P F YT LP++ GT L P
Sbjct: 207 ELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVKLPENVSIGT-LVIHP- 264
Query: 240 PISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVD 299
+A+D D G+N + YS + D I ++ +I +D + K V+
Sbjct: 265 --NASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMDFEESRAHKIP-VE 321
Query: 300 NPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEF 359
D+ Q T K S V E A G+V+ ++ + + +
Sbjct: 322 AVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVKEDAQLGTVIALISVIDLDADA 381
Query: 360 RESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSISND---TASI 416
F N ++L R+LD E+ S Y V D S TA +
Sbjct: 382 NGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSAYELVVTARDGGSPSLWATARV 441
Query: 417 NISVEDVNEWEPRFRHPQY 435
++ V DVN+ P F +Y
Sbjct: 442 SVEVADVNDNAPAFAQSEY 460
Score = 79.4 bits (187), Expect = 5e-14
Identities = 104/450 (23%), Positives = 181/450 (40%), Gaps = 40/450 (8%)
Query: 7 ESFFISEDTPIGSIIGTLSVNGDPSEDLGD---ITLRLQEKGAAVGIVPGSKN------L 57
++ FI+E P+ S + G D+G+ +T RL VP S L
Sbjct: 138 KNLFIAESRPLDS---RFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVKPLGL 194
Query: 58 TLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRV 117
L + LDREE +++ + + + + + + V D NDNAP ++ Y V++
Sbjct: 195 VLRKLLDREET---PELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVKL 251
Query: 118 SETXXXXXXXXXXXXSDRDQPGPHSALHYA----VLPGPHSEYLGFENELEPIIVVKKPL 173
E SD D+ G + + Y+ V P S++ + L I V +
Sbjct: 252 PENVSIGTLVIHPNASDLDE-GLNGDIIYSFSSDVSPDIKSKF--HMDPLSGAITVIGHM 308
Query: 174 DFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTF 233
DFE I + D+G PPL TL V V+D +D P+ T + + + +DA+ GT
Sbjct: 309 DFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVKEDAQLGTV 368
Query: 234 LTTSPGPISAADQDLGINAPLQYSSTGDHK-QLIVVNKDTGQVAATKQLIAELDPSVTIV 292
+ IS D D N + S T +L+ K+ + + L E + +V
Sbjct: 369 IAL----ISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSAYELV 424
Query: 293 LKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTT 352
+ A +P +A A + F Q +Y+ V E PG + T++
Sbjct: 425 VTARDGGSPSLWATARVSVEVADVNDNAPA-----FAQSEYTVFVKENNPPGCHIFTVSA 479
Query: 353 ----VPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTD 407
+N S ++ + +RS +++ +G+V + LD+E +QV D
Sbjct: 480 RDADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARD 539
Query: 408 S---ISNDTASINISVEDVNEWEPRFRHPQ 434
+ ++ + V D N+ P P+
Sbjct: 540 AGVPPLGSNVTLQVFVLDENDNAPALLTPR 569
Score = 70.9 bits (166), Expect = 2e-11
Identities = 88/317 (27%), Positives = 127/317 (40%), Gaps = 28/317 (8%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKN---LTLLRALDREE 67
+ ED +G++I +SV ++ G +T L +V KN L L RALDRE
Sbjct: 359 VKEDAQLGTVIALISVIDLDADANGQVTCSLTPH-VPFKLVSTYKNYYSLVLDRALDRES 417
Query: 68 KIGPSNVYVNVRCDRRRTTDPSF--VIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXX 125
+ + V R PS VSV V DVNDNAP + + Y V V E
Sbjct: 418 -VSAYELVVTARDGG----SPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGC 472
Query: 126 XXXXXXXSDRDQPGPHSALHYAVLP---GPHS--EYLGFENELEPIIVVKKPLDFETVNN 180
D D ++ + Y+++ G S Y+ E + ++ PLD E +
Sbjct: 473 HIFTVSARDADAQ-ENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQ-PLDHEELEL 530
Query: 181 FTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSP-- 238
++ +D G PPL S+ TLQV VLD +D P D A L +
Sbjct: 531 LQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLTPRMRGT--DGAVSEMVLRSVGAG 588
Query: 239 ---GPISAADQDLGINAPLQYS---STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIV 292
G + A D D G NA L Y T V TG+++ T+ L P ++
Sbjct: 589 VVVGKVRAVDADSGYNAWLSYELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLL 648
Query: 293 LKATQVDNPDRYALATL 309
+ P A AT+
Sbjct: 649 VLVKDHGEPALTATATV 665
>BC104802-1|AAI04803.1| 950|Homo sapiens protocadherin alpha 9
protein.
Length = 950
Score = 93.1 bits (221), Expect = 4e-18
Identities = 108/439 (24%), Positives = 177/439 (40%), Gaps = 23/439 (5%)
Query: 9 FFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAAVGIVPGSKN--LTLLRALDR 65
+ + E+ G+ +G ++ + G +L +L KG + +N L + +DR
Sbjct: 33 YSVPEEAEHGTFVGRIAQDLGLELAELVPRLFQLDSKGRGDLLEVNLQNGILFVNSRIDR 92
Query: 66 EEKIGPS---NVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXX 122
EE G S ++++ V DR P V V V V D+NDN P + + ++E+
Sbjct: 93 EELCGRSAECSIHLEVIVDR-----PLQVFHVDVEVKDINDNPPVFPATQKNLFIAESRP 147
Query: 123 XXXXXXXXXXSDRDQPGPHSALHYAVLPGPHS--EYLGFENELEPI-IVVKKPLDFETVN 179
SD D G ++ L Y + P + + +++P+ +V++K LD E
Sbjct: 148 LDSRFPLEGASDADI-GENALLTYRLSPNEYFFLDVPTSNQQVKPLGLVLRKLLDREETP 206
Query: 180 NFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPG 239
+ L D G P L L +TVLD +D P F YT LP++ GT L P
Sbjct: 207 ELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVKLPENVSIGT-LVIHP- 264
Query: 240 PISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVD 299
+A+D D G+N + YS + D I ++ +I +D + K V+
Sbjct: 265 --NASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMDFEESRAHKIP-VE 321
Query: 300 NPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEF 359
D+ Q T K S V E A G+V+ ++ + + +
Sbjct: 322 AVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVKEDAQLGTVIALISVIDLDADA 381
Query: 360 RESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSISND---TASI 416
F N ++L R+LD E+ S Y V D S TA +
Sbjct: 382 NGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSAYELVVTARDGGSPSLWATARV 441
Query: 417 NISVEDVNEWEPRFRHPQY 435
++ V DVN+ P F +Y
Sbjct: 442 SVEVADVNDNAPAFAQSEY 460
Score = 79.4 bits (187), Expect = 5e-14
Identities = 104/450 (23%), Positives = 181/450 (40%), Gaps = 40/450 (8%)
Query: 7 ESFFISEDTPIGSIIGTLSVNGDPSEDLGD---ITLRLQEKGAAVGIVPGSKN------L 57
++ FI+E P+ S + G D+G+ +T RL VP S L
Sbjct: 138 KNLFIAESRPLDS---RFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVKPLGL 194
Query: 58 TLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRV 117
L + LDREE +++ + + + + + + V D NDNAP ++ Y V++
Sbjct: 195 VLRKLLDREET---PELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVKL 251
Query: 118 SETXXXXXXXXXXXXSDRDQPGPHSALHYA----VLPGPHSEYLGFENELEPIIVVKKPL 173
E SD D+ G + + Y+ V P S++ + L I V +
Sbjct: 252 PENVSIGTLVIHPNASDLDE-GLNGDIIYSFSSDVSPDIKSKF--HMDPLSGAITVIGHM 308
Query: 174 DFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTF 233
DFE I + D+G PPL TL V V+D +D P+ T + + + +DA+ GT
Sbjct: 309 DFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVKEDAQLGTV 368
Query: 234 LTTSPGPISAADQDLGINAPLQYSSTGDHK-QLIVVNKDTGQVAATKQLIAELDPSVTIV 292
+ IS D D N + S T +L+ K+ + + L E + +V
Sbjct: 369 IAL----ISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSAYELV 424
Query: 293 LKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTT 352
+ A +P +A A + F Q +Y+ V E PG + T++
Sbjct: 425 VTARDGGSPSLWATARVSVEVADVNDNAPA-----FAQSEYTVFVKENNPPGCHIFTVSA 479
Query: 353 ----VPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTD 407
+N S ++ + +RS +++ +G+V + LD+E +QV D
Sbjct: 480 RDADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARD 539
Query: 408 S---ISNDTASINISVEDVNEWEPRFRHPQ 434
+ ++ + V D N+ P P+
Sbjct: 540 AGVPPLGSNVTLQVFVLDENDNAPALLTPR 569
Score = 70.9 bits (166), Expect = 2e-11
Identities = 88/317 (27%), Positives = 127/317 (40%), Gaps = 28/317 (8%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKN---LTLLRALDREE 67
+ ED +G++I +SV ++ G +T L +V KN L L RALDRE
Sbjct: 359 VKEDAQLGTVIALISVIDLDADANGQVTCSLTPH-VPFKLVSTYKNYYSLVLDRALDRES 417
Query: 68 KIGPSNVYVNVRCDRRRTTDPSF--VIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXX 125
+ + V R PS VSV V DVNDNAP + + Y V V E
Sbjct: 418 -VSAYELVVTARDGG----SPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGC 472
Query: 126 XXXXXXXSDRDQPGPHSALHYAVLP---GPHS--EYLGFENELEPIIVVKKPLDFETVNN 180
D D ++ + Y+++ G S Y+ E + ++ PLD E +
Sbjct: 473 HIFTVSARDADAQ-ENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQ-PLDHEELEL 530
Query: 181 FTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSP-- 238
++ +D G PPL S+ TLQV VLD +D P D A L +
Sbjct: 531 LQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLTPRMRGT--DGAVSEMVLRSVGAG 588
Query: 239 ---GPISAADQDLGINAPLQYS---STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIV 292
G + A D D G NA L Y T V TG+++ T+ L P ++
Sbjct: 589 VVVGKVRAVDADSGYNAWLSYELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLL 648
Query: 293 LKATQVDNPDRYALATL 309
+ P A AT+
Sbjct: 649 VLVKDHGEPALTATATV 665
>BC099728-1|AAH99728.1| 798|Homo sapiens protocadherin beta 14
protein.
Length = 798
Score = 93.1 bits (221), Expect = 4e-18
Identities = 120/479 (25%), Positives = 181/479 (37%), Gaps = 32/479 (6%)
Query: 57 LTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVR 116
L L RALD E++ + + + + + S V ++V D+NDNAP++ + Y V+
Sbjct: 194 LVLDRALDYEQE---AELRLTLTAVDGGSPPKSGTTLVLIKVLDINDNAPEFPQSLYEVQ 250
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFE-NELEPIIVVKKPLDF 175
V E D D G + + Y FE N + + ++ PLDF
Sbjct: 251 VPEDRPLGSWIATISAKDLDA-GNYGKISYTFFHASEDIRKTFEINPISGEVNLRSPLDF 309
Query: 176 ETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLT 235
E + ++TI ++ D G L TL V V+D +D P+ T T +P++A E
Sbjct: 310 EVIQSYTINIQATDGGG--LSGKCTLLVKVMDINDNPPEVTISSITKRIPENASE----- 362
Query: 236 TSPGPISAADQDLGINAPLQYSSTGDHKQLIV--VNKDTGQVAATKQLIAELDPSVTIVL 293
T S DQD G N + S D+ + K+ + + K L E I +
Sbjct: 363 TLVALFSILDQDSGDNGRM-ICSIQDNLPFFLKPTFKNFFTLVSEKALDRESQAEYNITI 421
Query: 294 KATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASP----GSVLLT 349
T + P L T FTQ Y+ V E SP GSV T
Sbjct: 422 TVTDLGTP---RLKT--EYNITVLLSDVNDNAPTFTQTSYTLFVRENNSPALHIGSVSAT 476
Query: 350 LTTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTDS 408
N + S L +IN + G + RSLDYE + ++V TD
Sbjct: 477 DRDSGTNAQVNYSLLPPQDRHLPLASLVSINADNGHLFALRSLDYEALQEFEFRVGATDR 536
Query: 409 IS---NDTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGDA 465
S + A + + V D N+ P +P VA DGD+
Sbjct: 537 GSPALSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVTKVVAVDGDS 596
Query: 466 GTLA-LS---LAGQHARMFYINASGDLFLREEAIGNLNSSSLHLVATAIDSGIPPRQTS 520
G A LS L +F + A + +++ LV D+G PPR +
Sbjct: 597 GQNAWLSYQLLKATEPGLFGVWAHNGEVRTARLLSERDAAKHRLVVLVKDNGEPPRSAT 655
Score = 90.2 bits (214), Expect = 3e-17
Identities = 106/445 (23%), Positives = 186/445 (41%), Gaps = 39/445 (8%)
Query: 9 FFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRL----QEKGAAVGIVPGSKNLTLLRAL 63
+ ++E+T IGS + L+ + G E+L R+ +K + ++ G NL L L
Sbjct: 33 YSVAEETEIGSFVANLARDLGLGVEELSSREARVVSDDNKKYLHLDLLTG--NLLLNEKL 90
Query: 64 DREEKIG---PSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSET 120
DR+E G P ++ V + +P + V D+ND++P + +++SE
Sbjct: 91 DRDELCGSTEPCVLHFQVVLE-----NPLQFFRFELCVKDINDHSPTFLDKEILIKISEG 145
Query: 121 XXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGF----ENELEPIIVVKKPLDFE 176
D D G +S +Y + P H Y+ + ++ P +V+ + LD+E
Sbjct: 146 TTVGATFLMESAQDLDV-GSNSLQNYTISPNSHF-YIKIPDSSDRKIYPELVLDRALDYE 203
Query: 177 TVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTT 236
+ L D GSPP T + + VLD +D P+F Y +P+D G+++ T
Sbjct: 204 QEAELRLTLTAVDGGSPPKSGTTLVLIKVLDINDNAPEFPQSLYEVQVPEDRPLGSWIAT 263
Query: 237 SPGPISAADQDLGINAPLQYS---STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVL 293
ISA D D G + Y+ ++ D ++ +N +G+V L E+ S TI +
Sbjct: 264 ----ISAKDLDAGNYGKISYTFFHASEDIRKTFEINPISGEVNLRSPLDFEVIQSYTINI 319
Query: 294 KATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTV 353
+AT D TL T++ + E AS V L + +
Sbjct: 320 QAT--DGGGLSGKCTLLVKVMDINDNPPEVTISSITKR-----IPENASETLVAL-FSIL 371
Query: 354 PQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSIS--- 410
Q++ + + F K N ++ ++LD E+ + Y + VTD +
Sbjct: 372 DQDSGDNGRMICSIQDNLPFFLKPTFKNFFTLVSEKALDRESQAEYNITITVTDLGTPRL 431
Query: 411 NDTASINISVEDVNEWEPRFRHPQY 435
+I + + DVN+ P F Y
Sbjct: 432 KTEYNITVLLSDVNDNAPTFTQTSY 456
Score = 79.0 bits (186), Expect = 7e-14
Identities = 84/307 (27%), Positives = 132/307 (42%), Gaps = 27/307 (8%)
Query: 19 SIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLL---RALDREEKIGPSNVY 75
+++ S+ S D G + +Q+ + P KN L +ALDRE + +
Sbjct: 363 TLVALFSILDQDSGDNGRMICSIQDN-LPFFLKPTFKNFFTLVSEKALDRESQ---AEYN 418
Query: 76 VNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDR 135
+ + T ++V + DVNDNAP + Y + V E +DR
Sbjct: 419 ITITVTDLGTPRLKTEYNITVLLSDVNDNAPTFTQTSYTLFVRENNSPALHIGSVSATDR 478
Query: 136 DQPGPHSALHYAVLPGPHSEYLGFE-----NELEPIIVVKKPLDFETVNNFTIKLRVQDQ 190
D G ++ ++Y++LP P +L N + + LD+E + F ++ D+
Sbjct: 479 DS-GTNAQVNYSLLP-PQDRHLPLASLVSINADNGHLFALRSLDYEALQEFEFRVGATDR 536
Query: 191 GSPPLYSDTTLQVTVLDADDQNPKFTY------EHYTALLPDDAEEGTFLTTSPGPISAA 244
GSP L S+ ++V VLDA+D +P Y T L+P AE G +T + A
Sbjct: 537 GSPALSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVT----KVVAV 592
Query: 245 DQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPSV-TIVLKATQVDNPD 302
D D G NA L Y L V G+V T +L++E D + +V+ P
Sbjct: 593 DGDSGQNAWLSYQLLKATEPGLFGVWAHNGEV-RTARLLSERDAAKHRLVVLVKDNGEPP 651
Query: 303 RYALATL 309
R A ATL
Sbjct: 652 RSATATL 658
>BC098144-1|AAH98144.1| 797|Homo sapiens PCDHB14 protein protein.
Length = 797
Score = 93.1 bits (221), Expect = 4e-18
Identities = 120/479 (25%), Positives = 181/479 (37%), Gaps = 32/479 (6%)
Query: 57 LTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVR 116
L L RALD E++ + + + + + S V ++V D+NDNAP++ + Y V+
Sbjct: 193 LVLDRALDYEQE---AELRLTLTAVDGGSPPKSGTTLVLIKVLDINDNAPEFPQSLYEVQ 249
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFE-NELEPIIVVKKPLDF 175
V E D D G + + Y FE N + + ++ PLDF
Sbjct: 250 VPEDRPLGSWIATISAKDLDA-GNYGKISYTFFHASEDIRKTFEINPISGEVNLRSPLDF 308
Query: 176 ETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLT 235
E + ++TI ++ D G L TL V V+D +D P+ T T +P++A E
Sbjct: 309 EVIQSYTINIQATDGGG--LSGKCTLLVKVMDINDNPPEVTISSITKRIPENASE----- 361
Query: 236 TSPGPISAADQDLGINAPLQYSSTGDHKQLIV--VNKDTGQVAATKQLIAELDPSVTIVL 293
T S DQD G N + S D+ + K+ + + K L E I +
Sbjct: 362 TLVALFSILDQDSGDNGRM-ICSIQDNLPFFLKPTFKNFFTLVSEKALDRESQAEYNITI 420
Query: 294 KATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASP----GSVLLT 349
T + P L T FTQ Y+ V E SP GSV T
Sbjct: 421 TVTDLGTP---RLKT--EYNITVLLSDVNDNAPTFTQTSYTLFVRENNSPALHIGSVSAT 475
Query: 350 LTTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTDS 408
N + S L +IN + G + RSLDYE + ++V TD
Sbjct: 476 DRDSGTNAQVNYSLLPPQDRHLPLASLVSINADNGHLFALRSLDYEALQEFEFRVGATDR 535
Query: 409 IS---NDTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGDA 465
S + A + + V D N+ P +P VA DGD+
Sbjct: 536 GSPALSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVTKVVAVDGDS 595
Query: 466 GTLA-LS---LAGQHARMFYINASGDLFLREEAIGNLNSSSLHLVATAIDSGIPPRQTS 520
G A LS L +F + A + +++ LV D+G PPR +
Sbjct: 596 GQNAWLSYQLLKATEPGLFGVWAHNGEVRTARLLSERDAAKHRLVVLVKDNGEPPRSAT 654
Score = 90.2 bits (214), Expect = 3e-17
Identities = 106/445 (23%), Positives = 186/445 (41%), Gaps = 39/445 (8%)
Query: 9 FFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRL----QEKGAAVGIVPGSKNLTLLRAL 63
+ ++E+T IGS + L+ + G E+L R+ +K + ++ G NL L L
Sbjct: 32 YSVAEETEIGSFVANLARDLGLGVEELSSREARVVSDDNKKYLHLDLLTG--NLLLNEKL 89
Query: 64 DREEKIG---PSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSET 120
DR+E G P ++ V + +P + V D+ND++P + +++SE
Sbjct: 90 DRDELCGSTEPCVLHFQVVLE-----NPLQFFRFELCVKDINDHSPTFLDKEILIKISEG 144
Query: 121 XXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGF----ENELEPIIVVKKPLDFE 176
D D G +S +Y + P H Y+ + ++ P +V+ + LD+E
Sbjct: 145 TTVGATFLMESAQDLDV-GSNSLQNYTISPNSHF-YIKIPDSSDRKIYPELVLDRALDYE 202
Query: 177 TVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTT 236
+ L D GSPP T + + VLD +D P+F Y +P+D G+++ T
Sbjct: 203 QEAELRLTLTAVDGGSPPKSGTTLVLIKVLDINDNAPEFPQSLYEVQVPEDRPLGSWIAT 262
Query: 237 SPGPISAADQDLGINAPLQYS---STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVL 293
ISA D D G + Y+ ++ D ++ +N +G+V L E+ S TI +
Sbjct: 263 ----ISAKDLDAGNYGKISYTFFHASEDIRKTFEINPISGEVNLRSPLDFEVIQSYTINI 318
Query: 294 KATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTV 353
+AT D TL T++ + E AS V L + +
Sbjct: 319 QAT--DGGGLSGKCTLLVKVMDINDNPPEVTISSITKR-----IPENASETLVAL-FSIL 370
Query: 354 PQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSIS--- 410
Q++ + + F K N ++ ++LD E+ + Y + VTD +
Sbjct: 371 DQDSGDNGRMICSIQDNLPFFLKPTFKNFFTLVSEKALDRESQAEYNITITVTDLGTPRL 430
Query: 411 NDTASINISVEDVNEWEPRFRHPQY 435
+I + + DVN+ P F Y
Sbjct: 431 KTEYNITVLLSDVNDNAPTFTQTSY 455
Score = 79.0 bits (186), Expect = 7e-14
Identities = 84/307 (27%), Positives = 132/307 (42%), Gaps = 27/307 (8%)
Query: 19 SIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLL---RALDREEKIGPSNVY 75
+++ S+ S D G + +Q+ + P KN L +ALDRE + +
Sbjct: 362 TLVALFSILDQDSGDNGRMICSIQDN-LPFFLKPTFKNFFTLVSEKALDRESQ---AEYN 417
Query: 76 VNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDR 135
+ + T ++V + DVNDNAP + Y + V E +DR
Sbjct: 418 ITITVTDLGTPRLKTEYNITVLLSDVNDNAPTFTQTSYTLFVRENNSPALHIGSVSATDR 477
Query: 136 DQPGPHSALHYAVLPGPHSEYLGFE-----NELEPIIVVKKPLDFETVNNFTIKLRVQDQ 190
D G ++ ++Y++LP P +L N + + LD+E + F ++ D+
Sbjct: 478 DS-GTNAQVNYSLLP-PQDRHLPLASLVSINADNGHLFALRSLDYEALQEFEFRVGATDR 535
Query: 191 GSPPLYSDTTLQVTVLDADDQNPKFTY------EHYTALLPDDAEEGTFLTTSPGPISAA 244
GSP L S+ ++V VLDA+D +P Y T L+P AE G +T + A
Sbjct: 536 GSPALSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVT----KVVAV 591
Query: 245 DQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPSV-TIVLKATQVDNPD 302
D D G NA L Y L V G+V T +L++E D + +V+ P
Sbjct: 592 DGDSGQNAWLSYQLLKATEPGLFGVWAHNGEV-RTARLLSERDAAKHRLVVLVKDNGEPP 650
Query: 303 RYALATL 309
R A ATL
Sbjct: 651 RSATATL 657
>BC093879-1|AAH93879.1| 818|Homo sapiens protocadherin gamma
subfamily B, 5 protein.
Length = 818
Score = 93.1 bits (221), Expect = 4e-18
Identities = 105/435 (24%), Positives = 180/435 (41%), Gaps = 28/435 (6%)
Query: 11 ISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEKI 69
I E+ P GS++G L+ + G ++L LR+ + + S L + LDREE
Sbjct: 37 IPEEMPKGSVVGNLATDLGFSVQELPTRKLRVSSEKPYFTVSAESGELLVSSRLDREEIC 96
Query: 70 GPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXX 129
G +P V+V + D+ND+ P++ + +++SE+
Sbjct: 97 GKKPACALEF--EAVAENPLNFYHVNVEIEDINDHTPKFTQNSFELQISESAQPGTRFIL 154
Query: 130 XXXSDRDQPGPHSALHYAVLPGPHSEYLGFENE---LEPIIVVKKPLDFETVNNFTIKLR 186
D D G +S Y + P + E + P + ++K LD E + + L
Sbjct: 155 EVAEDADI-GLNSLQKYKLSLNPSFSLIIKEKQDGSKYPELALEKTLDREQQSYHRLVLT 213
Query: 187 VQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQ 246
D G PPL T L++ V DA+D P F + Y L ++ GT + +SA DQ
Sbjct: 214 ALDGGHPPLSGTTELRIQVTDANDNPPVFNRDVYRVSLRENVPPGTTVL----QVSATDQ 269
Query: 247 DLGINAPLQYS--STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRY 304
D GIN+ + YS TG Q+ +N +G++ K+L E ++V++ D
Sbjct: 270 DEGINSEITYSFYRTG---QIFSLNSKSGEITTQKKLDFEETKEYSMVVEGR--DGGGLV 324
Query: 305 ALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNT-EFRESP 363
A T+ + T + E A PG+++ + Q++ E E
Sbjct: 325 AQCTVEINIQDENDNSP-----EVTFHSLLEMILENAVPGTLIALIKIHDQDSGENGEVN 379
Query: 364 LQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSIS---NDTASINISV 420
Q + F + N+ +++ +LD E T Y + TD + + S+ + +
Sbjct: 380 CQLQ-GEVPFKIISSSKNSYKLVTDGTLDREQTPEYNVTITATDRGKPPLSSSISVILHI 438
Query: 421 EDVNEWEPRFRHPQY 435
DVN+ P F Y
Sbjct: 439 RDVNDNAPVFHQASY 453
Score = 77.8 bits (183), Expect = 2e-13
Identities = 78/287 (27%), Positives = 125/287 (43%), Gaps = 26/287 (9%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKN---LTLLRALDREE 67
I E+ G++I + ++ S + G++ +LQ + I+ SKN L LDRE+
Sbjct: 352 ILENAVPGTLIALIKIHDQDSGENGEVNCQLQGE-VPFKIISSSKNSYKLVTDGTLDREQ 410
Query: 68 KIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXX 127
V + R S I V + + DVNDNAP + A Y V V E
Sbjct: 411 T---PEYNVTITATDRGKPPLSSSISVILHIRDVNDNAPVFHQASYLVSVPENNPPGASI 467
Query: 128 XXXXXSDRDQPGPHSALHYAVL-----PGPHSEYLGFENELEPIIVVKKPLDFETVNNFT 182
SD D G + + Y+++ P + Y+ + ++ ++ D+E + F
Sbjct: 468 AQVCASDLDL-GLNGQVSYSIMASDLEPLALASYVSMSAQ-SGVVFAQRAFDYEQLRTFE 525
Query: 183 IKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHY----TAL---LPDDAEEGTFLT 235
+ L+ +DQGSP L ++ +L+V V D +D P+ Y +AL +P AE G +T
Sbjct: 526 LTLQARDQGSPALSANVSLRVLVGDRNDNAPRVLYPALGPDGSALFDMVPRAAEPGYLVT 585
Query: 236 TSPGPISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQL 281
+ A D D G NA L Y L + TG+V + L
Sbjct: 586 ----KVVAVDADSGHNAWLSYHVLQASEPGLFSLGLRTGEVRTARAL 628
>BC093877-1|AAH93877.1| 818|Homo sapiens protocadherin gamma
subfamily B, 5 protein.
Length = 818
Score = 93.1 bits (221), Expect = 4e-18
Identities = 105/435 (24%), Positives = 180/435 (41%), Gaps = 28/435 (6%)
Query: 11 ISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEKI 69
I E+ P GS++G L+ + G ++L LR+ + + S L + LDREE
Sbjct: 37 IPEEMPKGSVVGNLATDLGFSVQELPTRKLRVSSEKPYFTVSAESGELLVSSRLDREEIC 96
Query: 70 GPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXX 129
G +P V+V + D+ND+ P++ + +++SE+
Sbjct: 97 GKKPACALEF--EAVAENPLNFYHVNVEIEDINDHTPKFTQNSFELQISESAQPGTRFIL 154
Query: 130 XXXSDRDQPGPHSALHYAVLPGPHSEYLGFENE---LEPIIVVKKPLDFETVNNFTIKLR 186
D D G +S Y + P + E + P + ++K LD E + + L
Sbjct: 155 EVAEDADI-GLNSLQKYKLSLNPSFSLIIKEKQDGSKYPELALEKTLDREQQSYHRLVLT 213
Query: 187 VQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQ 246
D G PPL T L++ V DA+D P F + Y L ++ GT + +SA DQ
Sbjct: 214 ALDGGHPPLSGTTELRIQVTDANDNPPVFNRDVYRVSLRENVPPGTTVL----QVSATDQ 269
Query: 247 DLGINAPLQYS--STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRY 304
D GIN+ + YS TG Q+ +N +G++ K+L E ++V++ D
Sbjct: 270 DEGINSEITYSFYRTG---QIFSLNSKSGEITTQKKLDFEETKEYSMVVEGR--DGGGLV 324
Query: 305 ALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNT-EFRESP 363
A T+ + T + E A PG+++ + Q++ E E
Sbjct: 325 AQCTVEINIQDENDNSP-----EVTFHSLLEMILENAVPGTLIALIKIHDQDSGENGEVN 379
Query: 364 LQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSIS---NDTASINISV 420
Q + F + N+ +++ +LD E T Y + TD + + S+ + +
Sbjct: 380 CQLQ-GEVPFKIISSSKNSYKLVTDGTLDREQTPEYNVTITATDRGKPPLSSSISVILHI 438
Query: 421 EDVNEWEPRFRHPQY 435
DVN+ P F Y
Sbjct: 439 RDVNDNAPVFHQASY 453
Score = 77.8 bits (183), Expect = 2e-13
Identities = 78/287 (27%), Positives = 125/287 (43%), Gaps = 26/287 (9%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKN---LTLLRALDREE 67
I E+ G++I + ++ S + G++ +LQ + I+ SKN L LDRE+
Sbjct: 352 ILENAVPGTLIALIKIHDQDSGENGEVNCQLQGE-VPFKIISSSKNSYKLVTDGTLDREQ 410
Query: 68 KIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXX 127
V + R S I V + + DVNDNAP + A Y V V E
Sbjct: 411 T---PEYNVTITATDRGKPPLSSSISVILHIRDVNDNAPVFHQASYLVSVPENNPPGASI 467
Query: 128 XXXXXSDRDQPGPHSALHYAVL-----PGPHSEYLGFENELEPIIVVKKPLDFETVNNFT 182
SD D G + + Y+++ P + Y+ + ++ ++ D+E + F
Sbjct: 468 AQVCASDLDL-GLNGQVSYSIMASDLEPLALASYVSMSAQ-SGVVFAQRAFDYEQLRTFE 525
Query: 183 IKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHY----TAL---LPDDAEEGTFLT 235
+ L+ +DQGSP L ++ +L+V V D +D P+ Y +AL +P AE G +T
Sbjct: 526 LTLQARDQGSPALSANVSLRVLVGDRNDNAPRVLYPALGPDGSALFDMVPRAAEPGYLVT 585
Query: 236 TSPGPISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQL 281
+ A D D G NA L Y L + TG+V + L
Sbjct: 586 ----KVVAVDADSGHNAWLSYHVLQASEPGLFSLGLRTGEVRTARAL 628
>AJ007610-1|CAC22257.1| 950|Homo sapiens protocadherin alpha 9
protein.
Length = 950
Score = 93.1 bits (221), Expect = 4e-18
Identities = 108/439 (24%), Positives = 177/439 (40%), Gaps = 23/439 (5%)
Query: 9 FFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAAVGIVPGSKN--LTLLRALDR 65
+ + E+ G+ +G ++ + G +L +L KG + +N L + +DR
Sbjct: 33 YSVPEEAEHGTFVGRIAQDLGLELAELVPRLFQLDSKGRGDLLEVNLQNGILFVNSRIDR 92
Query: 66 EEKIGPS---NVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXX 122
EE G S ++++ V DR P V V V V D+NDN P + + ++E+
Sbjct: 93 EELCGRSAECSIHLEVIVDR-----PLQVFHVDVEVKDINDNPPVFPATQKNLFIAESRP 147
Query: 123 XXXXXXXXXXSDRDQPGPHSALHYAVLPGPHS--EYLGFENELEPI-IVVKKPLDFETVN 179
SD D G ++ L Y + P + + +++P+ +V++K LD E
Sbjct: 148 LDSRFPLEGASDADI-GENALLTYRLSPNEYFFLDVPTSNQQVKPLGLVLRKLLDREETP 206
Query: 180 NFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPG 239
+ L D G P L L +TVLD +D P F YT LP++ GT L P
Sbjct: 207 ELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVKLPENVSIGT-LVIHP- 264
Query: 240 PISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVD 299
+A+D D G+N + YS + D I ++ +I +D + K V+
Sbjct: 265 --NASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMDFEESRAHKIP-VE 321
Query: 300 NPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEF 359
D+ Q T K S V E A G+V+ ++ + + +
Sbjct: 322 AVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVKEDAQLGTVIALISVIDLDADA 381
Query: 360 RESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSISND---TASI 416
F N ++L R+LD E+ S Y V D S TA +
Sbjct: 382 NGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSAYELVVTARDGGSPSLWATARV 441
Query: 417 NISVEDVNEWEPRFRHPQY 435
++ V DVN+ P F +Y
Sbjct: 442 SVEVADVNDNAPAFAQSEY 460
Score = 79.4 bits (187), Expect = 5e-14
Identities = 104/450 (23%), Positives = 181/450 (40%), Gaps = 40/450 (8%)
Query: 7 ESFFISEDTPIGSIIGTLSVNGDPSEDLGD---ITLRLQEKGAAVGIVPGSKN------L 57
++ FI+E P+ S + G D+G+ +T RL VP S L
Sbjct: 138 KNLFIAESRPLDS---RFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVKPLGL 194
Query: 58 TLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRV 117
L + LDREE +++ + + + + + + V D NDNAP ++ Y V++
Sbjct: 195 VLRKLLDREET---PELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVKL 251
Query: 118 SETXXXXXXXXXXXXSDRDQPGPHSALHYA----VLPGPHSEYLGFENELEPIIVVKKPL 173
E SD D+ G + + Y+ V P S++ + L I V +
Sbjct: 252 PENVSIGTLVIHPNASDLDE-GLNGDIIYSFSSDVSPDIKSKF--HMDPLSGAITVIGHM 308
Query: 174 DFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTF 233
DFE I + D+G PPL TL V V+D +D P+ T + + + +DA+ GT
Sbjct: 309 DFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVKEDAQLGTV 368
Query: 234 LTTSPGPISAADQDLGINAPLQYSSTGDHK-QLIVVNKDTGQVAATKQLIAELDPSVTIV 292
+ IS D D N + S T +L+ K+ + + L E + +V
Sbjct: 369 IAL----ISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSAYELV 424
Query: 293 LKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTT 352
+ A +P +A A + F Q +Y+ V E PG + T++
Sbjct: 425 VTARDGGSPSLWATARVSVEVADVNDNAPA-----FAQSEYTVFVKENNPPGCHIFTVSA 479
Query: 353 ----VPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTD 407
+N S ++ + +RS +++ +G+V + LD+E +QV D
Sbjct: 480 RDADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARD 539
Query: 408 S---ISNDTASINISVEDVNEWEPRFRHPQ 434
+ ++ + V D N+ P P+
Sbjct: 540 AGVPPLGSNVTLQVFVLDENDNAPALLTPR 569
Score = 70.9 bits (166), Expect = 2e-11
Identities = 88/317 (27%), Positives = 127/317 (40%), Gaps = 28/317 (8%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKN---LTLLRALDREE 67
+ ED +G++I +SV ++ G +T L +V KN L L RALDRE
Sbjct: 359 VKEDAQLGTVIALISVIDLDADANGQVTCSLTPH-VPFKLVSTYKNYYSLVLDRALDRES 417
Query: 68 KIGPSNVYVNVRCDRRRTTDPSF--VIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXX 125
+ + V R PS VSV V DVNDNAP + + Y V V E
Sbjct: 418 -VSAYELVVTARDGG----SPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGC 472
Query: 126 XXXXXXXSDRDQPGPHSALHYAVLP---GPHS--EYLGFENELEPIIVVKKPLDFETVNN 180
D D ++ + Y+++ G S Y+ E + ++ PLD E +
Sbjct: 473 HIFTVSARDADAQ-ENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQ-PLDHEELEL 530
Query: 181 FTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSP-- 238
++ +D G PPL S+ TLQV VLD +D P D A L +
Sbjct: 531 LQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLTPRMRGT--DGAVSEMVLRSVGAG 588
Query: 239 ---GPISAADQDLGINAPLQYS---STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIV 292
G + A D D G NA L Y T V TG+++ T+ L P ++
Sbjct: 589 VVVGKVRAVDADSGYNAWLSYELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLL 648
Query: 293 LKATQVDNPDRYALATL 309
+ P A AT+
Sbjct: 649 VLVKDHGEPALTATATV 665
>AF217744-1|AAK51612.1| 798|Homo sapiens protocadherin-beta14
protein.
Length = 798
Score = 93.1 bits (221), Expect = 4e-18
Identities = 120/479 (25%), Positives = 181/479 (37%), Gaps = 32/479 (6%)
Query: 57 LTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVR 116
L L RALD E++ + + + + + S V ++V D+NDNAP++ + Y V+
Sbjct: 194 LVLDRALDYEQE---AELRLTLTAVDGGSPPKSGTTLVLIKVLDINDNAPEFPQSLYEVQ 250
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFE-NELEPIIVVKKPLDF 175
V E D D G + + Y FE N + + ++ PLDF
Sbjct: 251 VPEDRPLGSWIATISAKDLDA-GNYGKISYTFFHASEDIRKTFEINPISGEVNLRSPLDF 309
Query: 176 ETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLT 235
E + ++TI ++ D G L TL V V+D +D P+ T T +P++A E
Sbjct: 310 EVIQSYTINIQATDGGG--LSGKCTLLVKVMDINDNPPEVTISSITKRIPENASE----- 362
Query: 236 TSPGPISAADQDLGINAPLQYSSTGDHKQLIV--VNKDTGQVAATKQLIAELDPSVTIVL 293
T S DQD G N + S D+ + K+ + + K L E I +
Sbjct: 363 TLVALFSILDQDSGDNGRM-ICSIQDNLPFFLKPTFKNFFTLVSEKALDRESQAEYNITI 421
Query: 294 KATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASP----GSVLLT 349
T + P L T FTQ Y+ V E SP GSV T
Sbjct: 422 TVTDLGTP---RLKT--EYNITVLLSDVNDNAPTFTQTSYTLFVRENNSPALHIGSVSAT 476
Query: 350 LTTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTDS 408
N + S L +IN + G + RSLDYE + ++V TD
Sbjct: 477 DRDSGTNAQVNYSLLPPQDRHLPLASLVSINADNGHLFALRSLDYEALQEFEFRVGATDR 536
Query: 409 IS---NDTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGDA 465
S + A + + V D N+ P +P VA DGD+
Sbjct: 537 GSPALSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVTKVVAVDGDS 596
Query: 466 GTLA-LS---LAGQHARMFYINASGDLFLREEAIGNLNSSSLHLVATAIDSGIPPRQTS 520
G A LS L +F + A + +++ LV D+G PPR +
Sbjct: 597 GQNAWLSYQLLKATEPGLFGVWAHNGEVRTARLLSERDAAKHRLVVLVKDNGEPPRSAT 655
Score = 90.2 bits (214), Expect = 3e-17
Identities = 106/445 (23%), Positives = 186/445 (41%), Gaps = 39/445 (8%)
Query: 9 FFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRL----QEKGAAVGIVPGSKNLTLLRAL 63
+ ++E+T IGS + L+ + G E+L R+ +K + ++ G NL L L
Sbjct: 33 YSVAEETEIGSFVANLARDLGLGVEELSSREARVVSDDNKKYLHLDLLTG--NLLLNEKL 90
Query: 64 DREEKIG---PSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSET 120
DR+E G P ++ V + +P + V D+ND++P + +++SE
Sbjct: 91 DRDELCGSTEPCVLHFQVVLE-----NPLQFFRFELCVKDINDHSPTFLDKEILIKISEG 145
Query: 121 XXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGF----ENELEPIIVVKKPLDFE 176
D D G +S +Y + P H Y+ + ++ P +V+ + LD+E
Sbjct: 146 TTVGATFLMESAQDLDV-GSNSLQNYTISPNSHF-YIKIPDSSDRKIYPELVLDRALDYE 203
Query: 177 TVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTT 236
+ L D GSPP T + + VLD +D P+F Y +P+D G+++ T
Sbjct: 204 QEAELRLTLTAVDGGSPPKSGTTLVLIKVLDINDNAPEFPQSLYEVQVPEDRPLGSWIAT 263
Query: 237 SPGPISAADQDLGINAPLQYS---STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVL 293
ISA D D G + Y+ ++ D ++ +N +G+V L E+ S TI +
Sbjct: 264 ----ISAKDLDAGNYGKISYTFFHASEDIRKTFEINPISGEVNLRSPLDFEVIQSYTINI 319
Query: 294 KATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTV 353
+AT D TL T++ + E AS V L + +
Sbjct: 320 QAT--DGGGLSGKCTLLVKVMDINDNPPEVTISSITKR-----IPENASETLVAL-FSIL 371
Query: 354 PQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSIS--- 410
Q++ + + F K N ++ ++LD E+ + Y + VTD +
Sbjct: 372 DQDSGDNGRMICSIQDNLPFFLKPTFKNFFTLVSEKALDRESQAEYNITITVTDLGTPRL 431
Query: 411 NDTASINISVEDVNEWEPRFRHPQY 435
+I + + DVN+ P F Y
Sbjct: 432 KTEYNITVLLSDVNDNAPTFTQTSY 456
Score = 79.0 bits (186), Expect = 7e-14
Identities = 84/307 (27%), Positives = 132/307 (42%), Gaps = 27/307 (8%)
Query: 19 SIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLL---RALDREEKIGPSNVY 75
+++ S+ S D G + +Q+ + P KN L +ALDRE + +
Sbjct: 363 TLVALFSILDQDSGDNGRMICSIQDN-LPFFLKPTFKNFFTLVSEKALDRESQ---AEYN 418
Query: 76 VNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDR 135
+ + T ++V + DVNDNAP + Y + V E +DR
Sbjct: 419 ITITVTDLGTPRLKTEYNITVLLSDVNDNAPTFTQTSYTLFVRENNSPALHIGSVSATDR 478
Query: 136 DQPGPHSALHYAVLPGPHSEYLGFE-----NELEPIIVVKKPLDFETVNNFTIKLRVQDQ 190
D G ++ ++Y++LP P +L N + + LD+E + F ++ D+
Sbjct: 479 DS-GTNAQVNYSLLP-PQDRHLPLASLVSINADNGHLFALRSLDYEALQEFEFRVGATDR 536
Query: 191 GSPPLYSDTTLQVTVLDADDQNPKFTY------EHYTALLPDDAEEGTFLTTSPGPISAA 244
GSP L S+ ++V VLDA+D +P Y T L+P AE G +T + A
Sbjct: 537 GSPALSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVT----KVVAV 592
Query: 245 DQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPSV-TIVLKATQVDNPD 302
D D G NA L Y L V G+V T +L++E D + +V+ P
Sbjct: 593 DGDSGQNAWLSYQLLKATEPGLFGVWAHNGEV-RTARLLSERDAAKHRLVVLVKDNGEPP 651
Query: 303 RYALATL 309
R A ATL
Sbjct: 652 RSATATL 658
>AF152521-1|AAD43781.1| 818|Homo sapiens protocadherin gamma B5
short form protein protein.
Length = 818
Score = 93.1 bits (221), Expect = 4e-18
Identities = 105/435 (24%), Positives = 180/435 (41%), Gaps = 28/435 (6%)
Query: 11 ISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEKI 69
I E+ P GS++G L+ + G ++L LR+ + + S L + LDREE
Sbjct: 37 IPEEMPKGSVVGNLATDLGFSVQELPTRKLRVSSEKPYFTVSAESGELLVSSRLDREEIC 96
Query: 70 GPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXX 129
G +P V+V + D+ND+ P++ + +++SE+
Sbjct: 97 GKKPACALEF--EAVAENPLNFYHVNVEIEDINDHTPKFTQNSFELQISESAQPGTRFIL 154
Query: 130 XXXSDRDQPGPHSALHYAVLPGPHSEYLGFENE---LEPIIVVKKPLDFETVNNFTIKLR 186
D D G +S Y + P + E + P + ++K LD E + + L
Sbjct: 155 EVAEDADI-GLNSLQKYKLSLNPSFSLIIKEKQDGSKYPELALEKTLDREQQSYHRLVLT 213
Query: 187 VQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQ 246
D G PPL T L++ V DA+D P F + Y L ++ GT + +SA DQ
Sbjct: 214 ALDGGHPPLSGTTELRIQVTDANDNPPVFNRDVYRVSLRENVPPGTTVL----QVSATDQ 269
Query: 247 DLGINAPLQYS--STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRY 304
D GIN+ + YS TG Q+ +N +G++ K+L E ++V++ D
Sbjct: 270 DEGINSEITYSFYRTG---QIFSLNSKSGEITTQKKLDFEETKEYSMVVEGR--DGGGLV 324
Query: 305 ALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNT-EFRESP 363
A T+ + T + E A PG+++ + Q++ E E
Sbjct: 325 AQCTVEINIQDENDNSP-----EVTFHSLLEMILENAVPGTLIALIKIHDQDSGENGEVN 379
Query: 364 LQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSIS---NDTASINISV 420
Q + F + N+ +++ +LD E T Y + TD + + S+ + +
Sbjct: 380 CQLQ-GEVPFKIISSSKNSYKLVTDGTLDREQTPEYNVTITATDRGKPPLSSSISVILHI 438
Query: 421 EDVNEWEPRFRHPQY 435
DVN+ P F Y
Sbjct: 439 RDVNDNAPVFHQASY 453
Score = 77.8 bits (183), Expect = 2e-13
Identities = 78/287 (27%), Positives = 125/287 (43%), Gaps = 26/287 (9%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKN---LTLLRALDREE 67
I E+ G++I + ++ S + G++ +LQ + I+ SKN L LDRE+
Sbjct: 352 ILENAVPGTLIALIKIHDQDSGENGEVNCQLQGE-VPFKIISSSKNSYKLVTDGTLDREQ 410
Query: 68 KIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXX 127
V + R S I V + + DVNDNAP + A Y V V E
Sbjct: 411 T---PEYNVTITATDRGKPPLSSSISVILHIRDVNDNAPVFHQASYLVSVPENNPPGASI 467
Query: 128 XXXXXSDRDQPGPHSALHYAVL-----PGPHSEYLGFENELEPIIVVKKPLDFETVNNFT 182
SD D G + + Y+++ P + Y+ + ++ ++ D+E + F
Sbjct: 468 AQVCASDLDL-GLNGQVSYSIMASDLEPLALASYVSMSAQ-SGVVFAQRAFDYEQLRTFE 525
Query: 183 IKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHY----TAL---LPDDAEEGTFLT 235
+ L+ +DQGSP L ++ +L+V V D +D P+ Y +AL +P AE G +T
Sbjct: 526 LTLQARDQGSPALSANVSLRVLVGDRNDNAPRVLYPALGPDGSALFDMVPRAAEPGYLVT 585
Query: 236 TSPGPISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQL 281
+ A D D G NA L Y L + TG+V + L
Sbjct: 586 ----KVVAVDADSGHNAWLSYHVLQASEPGLFSLGLRTGEVRTARAL 628
>AF152493-1|AAD43754.1| 798|Homo sapiens protocadherin beta 14
protein.
Length = 798
Score = 93.1 bits (221), Expect = 4e-18
Identities = 120/479 (25%), Positives = 181/479 (37%), Gaps = 32/479 (6%)
Query: 57 LTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVR 116
L L RALD E++ + + + + + S V ++V D+NDNAP++ + Y V+
Sbjct: 194 LVLDRALDYEQE---AELRLTLTAVDGGSPPKSGTTLVLIKVLDINDNAPEFPQSLYEVQ 250
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFE-NELEPIIVVKKPLDF 175
V E D D G + + Y FE N + + ++ PLDF
Sbjct: 251 VPEDRPLGSWIATISAKDLDA-GNYGKISYTFFHASEDIRKTFEINPISGEVNLRSPLDF 309
Query: 176 ETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLT 235
E + ++TI ++ D G L TL V V+D +D P+ T T +P++A E
Sbjct: 310 EVIQSYTINIQATDGGG--LSGKCTLLVKVMDINDNPPEVTISSITKRIPENASE----- 362
Query: 236 TSPGPISAADQDLGINAPLQYSSTGDHKQLIV--VNKDTGQVAATKQLIAELDPSVTIVL 293
T S DQD G N + S D+ + K+ + + K L E I +
Sbjct: 363 TLVALFSILDQDSGDNGRM-ICSIQDNLPFFLKPTFKNFFTLVSEKALDRESQAEYNITI 421
Query: 294 KATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASP----GSVLLT 349
T + P L T FTQ Y+ V E SP GSV T
Sbjct: 422 TVTDLGTP---RLKT--EYNITVLLSDVNDNAPTFTQTSYTLFVRENNSPALHIGSVSAT 476
Query: 350 LTTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTDS 408
N + S L +IN + G + RSLDYE + ++V TD
Sbjct: 477 DRDSGTNAQVNYSLLPPQDRHLPLASLVSINADNGHLFALRSLDYEALQEFEFRVGATDR 536
Query: 409 IS---NDTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGDA 465
S + A + + V D N+ P +P VA DGD+
Sbjct: 537 GSPALSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVTKVVAVDGDS 596
Query: 466 GTLA-LS---LAGQHARMFYINASGDLFLREEAIGNLNSSSLHLVATAIDSGIPPRQTS 520
G A LS L +F + A + +++ LV D+G PPR +
Sbjct: 597 GQNAWLSYQLLKATEPGLFGVWAHNGEVRTARLLSERDAAKHRLVVLVKDNGEPPRSAT 655
Score = 90.2 bits (214), Expect = 3e-17
Identities = 106/445 (23%), Positives = 186/445 (41%), Gaps = 39/445 (8%)
Query: 9 FFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRL----QEKGAAVGIVPGSKNLTLLRAL 63
+ ++E+T IGS + L+ + G E+L R+ +K + ++ G NL L L
Sbjct: 33 YSVAEETEIGSFVANLARDLGLGVEELSSREARVVSDDNKKYLHLDLLTG--NLLLNEKL 90
Query: 64 DREEKIG---PSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSET 120
DR+E G P ++ V + +P + V D+ND++P + +++SE
Sbjct: 91 DRDELCGSTEPCVLHFQVVLE-----NPLQFFRFELCVKDINDHSPTFLDKEILIKISEG 145
Query: 121 XXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGF----ENELEPIIVVKKPLDFE 176
D D G +S +Y + P H Y+ + ++ P +V+ + LD+E
Sbjct: 146 TTVGATFLMESAQDLDV-GSNSLQNYTISPNSHF-YIKIPDSSDRKIYPELVLDRALDYE 203
Query: 177 TVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTT 236
+ L D GSPP T + + VLD +D P+F Y +P+D G+++ T
Sbjct: 204 QEAELRLTLTAVDGGSPPKSGTTLVLIKVLDINDNAPEFPQSLYEVQVPEDRPLGSWIAT 263
Query: 237 SPGPISAADQDLGINAPLQYS---STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVL 293
ISA D D G + Y+ ++ D ++ +N +G+V L E+ S TI +
Sbjct: 264 ----ISAKDLDAGNYGKISYTFFHASEDIRKTFEINPISGEVNLRSPLDFEVIQSYTINI 319
Query: 294 KATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTV 353
+AT D TL T++ + E AS V L + +
Sbjct: 320 QAT--DGGGLSGKCTLLVKVMDINDNPPEVTISSITKR-----IPENASETLVAL-FSIL 371
Query: 354 PQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSIS--- 410
Q++ + + F K N ++ ++LD E+ + Y + VTD +
Sbjct: 372 DQDSGDNGRMICSIQDNLPFFLKPTFKNFFTLVSEKALDRESQAEYNITITVTDLGTPRL 431
Query: 411 NDTASINISVEDVNEWEPRFRHPQY 435
+I + + DVN+ P F Y
Sbjct: 432 KTEYNITVLLSDVNDNAPTFTQTSY 456
Score = 79.0 bits (186), Expect = 7e-14
Identities = 84/307 (27%), Positives = 132/307 (42%), Gaps = 27/307 (8%)
Query: 19 SIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLL---RALDREEKIGPSNVY 75
+++ S+ S D G + +Q+ + P KN L +ALDRE + +
Sbjct: 363 TLVALFSILDQDSGDNGRMICSIQDN-LPFFLKPTFKNFFTLVSEKALDRESQ---AEYN 418
Query: 76 VNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDR 135
+ + T ++V + DVNDNAP + Y + V E +DR
Sbjct: 419 ITITVTDLGTPRLKTEYNITVLLSDVNDNAPTFTQTSYTLFVRENNSPALHIGSVSATDR 478
Query: 136 DQPGPHSALHYAVLPGPHSEYLGFE-----NELEPIIVVKKPLDFETVNNFTIKLRVQDQ 190
D G ++ ++Y++LP P +L N + + LD+E + F ++ D+
Sbjct: 479 DS-GTNAQVNYSLLP-PQDRHLPLASLVSINADNGHLFALRSLDYEALQEFEFRVGATDR 536
Query: 191 GSPPLYSDTTLQVTVLDADDQNPKFTY------EHYTALLPDDAEEGTFLTTSPGPISAA 244
GSP L S+ ++V VLDA+D +P Y T L+P AE G +T + A
Sbjct: 537 GSPALSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVT----KVVAV 592
Query: 245 DQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPSV-TIVLKATQVDNPD 302
D D G NA L Y L V G+V T +L++E D + +V+ P
Sbjct: 593 DGDSGQNAWLSYQLLKATEPGLFGVWAHNGEV-RTARLLSERDAAKHRLVVLVKDNGEPP 651
Query: 303 RYALATL 309
R A ATL
Sbjct: 652 RSATATL 658
>AF152487-1|AAD43748.1| 842|Homo sapiens protocadherin alpha 9
short form protein protein.
Length = 842
Score = 93.1 bits (221), Expect = 4e-18
Identities = 108/439 (24%), Positives = 177/439 (40%), Gaps = 23/439 (5%)
Query: 9 FFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAAVGIVPGSKN--LTLLRALDR 65
+ + E+ G+ +G ++ + G +L +L KG + +N L + +DR
Sbjct: 33 YSVPEEAEHGTFVGRIAQDLGLELAELVPRLFQLDSKGRGDLLEVNLQNGILFVNSRIDR 92
Query: 66 EEKIGPS---NVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXX 122
EE G S ++++ V DR P V V V V D+NDN P + + ++E+
Sbjct: 93 EELCGRSAECSIHLEVIVDR-----PLQVFHVDVEVKDINDNPPVFPATQKNLFIAESRP 147
Query: 123 XXXXXXXXXXSDRDQPGPHSALHYAVLPGPHS--EYLGFENELEPI-IVVKKPLDFETVN 179
SD D G ++ L Y + P + + +++P+ +V++K LD E
Sbjct: 148 LDSRFPLEGASDADI-GENALLTYRLSPNEYFFLDVPTSNQQVKPLGLVLRKLLDREETP 206
Query: 180 NFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPG 239
+ L D G P L L +TVLD +D P F YT LP++ GT L P
Sbjct: 207 ELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVKLPENVSIGT-LVIHP- 264
Query: 240 PISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVD 299
+A+D D G+N + YS + D I ++ +I +D + K V+
Sbjct: 265 --NASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMDFEESRAHKIP-VE 321
Query: 300 NPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEF 359
D+ Q T K S V E A G+V+ ++ + + +
Sbjct: 322 AVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVKEDAQLGTVIALISVIDLDADA 381
Query: 360 RESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSISND---TASI 416
F N ++L R+LD E+ S Y V D S TA +
Sbjct: 382 NGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSAYELVVTARDGGSPSLWATARV 441
Query: 417 NISVEDVNEWEPRFRHPQY 435
++ V DVN+ P F +Y
Sbjct: 442 SVEVADVNDNAPAFAQSEY 460
Score = 79.4 bits (187), Expect = 5e-14
Identities = 104/450 (23%), Positives = 181/450 (40%), Gaps = 40/450 (8%)
Query: 7 ESFFISEDTPIGSIIGTLSVNGDPSEDLGD---ITLRLQEKGAAVGIVPGSKN------L 57
++ FI+E P+ S + G D+G+ +T RL VP S L
Sbjct: 138 KNLFIAESRPLDS---RFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVKPLGL 194
Query: 58 TLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRV 117
L + LDREE +++ + + + + + + V D NDNAP ++ Y V++
Sbjct: 195 VLRKLLDREET---PELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVKL 251
Query: 118 SETXXXXXXXXXXXXSDRDQPGPHSALHYA----VLPGPHSEYLGFENELEPIIVVKKPL 173
E SD D+ G + + Y+ V P S++ + L I V +
Sbjct: 252 PENVSIGTLVIHPNASDLDE-GLNGDIIYSFSSDVSPDIKSKF--HMDPLSGAITVIGHM 308
Query: 174 DFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTF 233
DFE I + D+G PPL TL V V+D +D P+ T + + + +DA+ GT
Sbjct: 309 DFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVKEDAQLGTV 368
Query: 234 LTTSPGPISAADQDLGINAPLQYSSTGDHK-QLIVVNKDTGQVAATKQLIAELDPSVTIV 292
+ IS D D N + S T +L+ K+ + + L E + +V
Sbjct: 369 IAL----ISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSAYELV 424
Query: 293 LKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTT 352
+ A +P +A A + F Q +Y+ V E PG + T++
Sbjct: 425 VTARDGGSPSLWATARVSVEVADVNDNAPA-----FAQSEYTVFVKENNPPGCHIFTVSA 479
Query: 353 ----VPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTD 407
+N S ++ + +RS +++ +G+V + LD+E +QV D
Sbjct: 480 RDADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARD 539
Query: 408 S---ISNDTASINISVEDVNEWEPRFRHPQ 434
+ ++ + V D N+ P P+
Sbjct: 540 AGVPPLGSNVTLQVFVLDENDNAPALLTPR 569
Score = 70.9 bits (166), Expect = 2e-11
Identities = 88/317 (27%), Positives = 127/317 (40%), Gaps = 28/317 (8%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKN---LTLLRALDREE 67
+ ED +G++I +SV ++ G +T L +V KN L L RALDRE
Sbjct: 359 VKEDAQLGTVIALISVIDLDADANGQVTCSLTPH-VPFKLVSTYKNYYSLVLDRALDRES 417
Query: 68 KIGPSNVYVNVRCDRRRTTDPSF--VIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXX 125
+ + V R PS VSV V DVNDNAP + + Y V V E
Sbjct: 418 -VSAYELVVTARDGG----SPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGC 472
Query: 126 XXXXXXXSDRDQPGPHSALHYAVLP---GPHS--EYLGFENELEPIIVVKKPLDFETVNN 180
D D ++ + Y+++ G S Y+ E + ++ PLD E +
Sbjct: 473 HIFTVSARDADAQ-ENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQ-PLDHEELEL 530
Query: 181 FTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSP-- 238
++ +D G PPL S+ TLQV VLD +D P D A L +
Sbjct: 531 LQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLTPRMRGT--DGAVSEMVLRSVGAG 588
Query: 239 ---GPISAADQDLGINAPLQYS---STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIV 292
G + A D D G NA L Y T V TG+++ T+ L P ++
Sbjct: 589 VVVGKVRAVDADSGYNAWLSYELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLL 648
Query: 293 LKATQVDNPDRYALATL 309
+ P A AT+
Sbjct: 649 VLVKDHGEPALTATATV 665
>AF152334-1|AAD43728.1| 923|Homo sapiens protocadherin gamma B5
protein.
Length = 923
Score = 93.1 bits (221), Expect = 4e-18
Identities = 105/435 (24%), Positives = 180/435 (41%), Gaps = 28/435 (6%)
Query: 11 ISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEKI 69
I E+ P GS++G L+ + G ++L LR+ + + S L + LDREE
Sbjct: 37 IPEEMPKGSVVGNLATDLGFSVQELPTRKLRVSSEKPYFTVSAESGELLVSSRLDREEIC 96
Query: 70 GPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXX 129
G +P V+V + D+ND+ P++ + +++SE+
Sbjct: 97 GKKPACALEF--EAVAENPLNFYHVNVEIEDINDHTPKFTQNSFELQISESAQPGTRFIL 154
Query: 130 XXXSDRDQPGPHSALHYAVLPGPHSEYLGFENE---LEPIIVVKKPLDFETVNNFTIKLR 186
D D G +S Y + P + E + P + ++K LD E + + L
Sbjct: 155 EVAEDADI-GLNSLQKYKLSLNPSFSLIIKEKQDGSKYPELALEKTLDREQQSYHRLVLT 213
Query: 187 VQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQ 246
D G PPL T L++ V DA+D P F + Y L ++ GT + +SA DQ
Sbjct: 214 ALDGGHPPLSGTTELRIQVTDANDNPPVFNRDVYRVSLRENVPPGTTVL----QVSATDQ 269
Query: 247 DLGINAPLQYS--STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRY 304
D GIN+ + YS TG Q+ +N +G++ K+L E ++V++ D
Sbjct: 270 DEGINSEITYSFYRTG---QIFSLNSKSGEITTQKKLDFEETKEYSMVVEGR--DGGGLV 324
Query: 305 ALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNT-EFRESP 363
A T+ + T + E A PG+++ + Q++ E E
Sbjct: 325 AQCTVEINIQDENDNSP-----EVTFHSLLEMILENAVPGTLIALIKIHDQDSGENGEVN 379
Query: 364 LQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSIS---NDTASINISV 420
Q + F + N+ +++ +LD E T Y + TD + + S+ + +
Sbjct: 380 CQLQ-GEVPFKIISSSKNSYKLVTDGTLDREQTPEYNVTITATDRGKPPLSSSISVILHI 438
Query: 421 EDVNEWEPRFRHPQY 435
DVN+ P F Y
Sbjct: 439 RDVNDNAPVFHQASY 453
Score = 77.8 bits (183), Expect = 2e-13
Identities = 78/287 (27%), Positives = 125/287 (43%), Gaps = 26/287 (9%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKN---LTLLRALDREE 67
I E+ G++I + ++ S + G++ +LQ + I+ SKN L LDRE+
Sbjct: 352 ILENAVPGTLIALIKIHDQDSGENGEVNCQLQGE-VPFKIISSSKNSYKLVTDGTLDREQ 410
Query: 68 KIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXX 127
V + R S I V + + DVNDNAP + A Y V V E
Sbjct: 411 T---PEYNVTITATDRGKPPLSSSISVILHIRDVNDNAPVFHQASYLVSVPENNPPGASI 467
Query: 128 XXXXXSDRDQPGPHSALHYAVL-----PGPHSEYLGFENELEPIIVVKKPLDFETVNNFT 182
SD D G + + Y+++ P + Y+ + ++ ++ D+E + F
Sbjct: 468 AQVCASDLDL-GLNGQVSYSIMASDLEPLALASYVSMSAQ-SGVVFAQRAFDYEQLRTFE 525
Query: 183 IKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHY----TAL---LPDDAEEGTFLT 235
+ L+ +DQGSP L ++ +L+V V D +D P+ Y +AL +P AE G +T
Sbjct: 526 LTLQARDQGSPALSANVSLRVLVGDRNDNAPRVLYPALGPDGSALFDMVPRAAEPGYLVT 585
Query: 236 TSPGPISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQL 281
+ A D D G NA L Y L + TG+V + L
Sbjct: 586 ----KVVAVDADSGHNAWLSYHVLQASEPGLFSLGLRTGEVRTARAL 628
>AF152317-1|AAD43711.1| 950|Homo sapiens protocadherin alpha 9
protein.
Length = 950
Score = 93.1 bits (221), Expect = 4e-18
Identities = 108/439 (24%), Positives = 177/439 (40%), Gaps = 23/439 (5%)
Query: 9 FFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAAVGIVPGSKN--LTLLRALDR 65
+ + E+ G+ +G ++ + G +L +L KG + +N L + +DR
Sbjct: 33 YSVPEEAEHGTFVGRIAQDLGLELAELVPRLFQLDSKGRGDLLEVNLQNGILFVNSRIDR 92
Query: 66 EEKIGPS---NVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXX 122
EE G S ++++ V DR P V V V V D+NDN P + + ++E+
Sbjct: 93 EELCGRSAECSIHLEVIVDR-----PLQVFHVDVEVKDINDNPPVFPATQKNLFIAESRP 147
Query: 123 XXXXXXXXXXSDRDQPGPHSALHYAVLPGPHS--EYLGFENELEPI-IVVKKPLDFETVN 179
SD D G ++ L Y + P + + +++P+ +V++K LD E
Sbjct: 148 LDSRFPLEGASDADI-GENALLTYRLSPNEYFFLDVPTSNQQVKPLGLVLRKLLDREETP 206
Query: 180 NFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPG 239
+ L D G P L L +TVLD +D P F YT LP++ GT L P
Sbjct: 207 ELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVKLPENVSIGT-LVIHP- 264
Query: 240 PISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVD 299
+A+D D G+N + YS + D I ++ +I +D + K V+
Sbjct: 265 --NASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMDFEESRAHKIP-VE 321
Query: 300 NPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEF 359
D+ Q T K S V E A G+V+ ++ + + +
Sbjct: 322 AVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVKEDAQLGTVIALISVIDLDADA 381
Query: 360 RESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSISND---TASI 416
F N ++L R+LD E+ S Y V D S TA +
Sbjct: 382 NGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSAYELVVTARDGGSPSLWATARV 441
Query: 417 NISVEDVNEWEPRFRHPQY 435
++ V DVN+ P F +Y
Sbjct: 442 SVEVADVNDNAPAFAQSEY 460
Score = 79.4 bits (187), Expect = 5e-14
Identities = 104/450 (23%), Positives = 181/450 (40%), Gaps = 40/450 (8%)
Query: 7 ESFFISEDTPIGSIIGTLSVNGDPSEDLGD---ITLRLQEKGAAVGIVPGSKN------L 57
++ FI+E P+ S + G D+G+ +T RL VP S L
Sbjct: 138 KNLFIAESRPLDS---RFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVKPLGL 194
Query: 58 TLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRV 117
L + LDREE +++ + + + + + + V D NDNAP ++ Y V++
Sbjct: 195 VLRKLLDREET---PELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVKL 251
Query: 118 SETXXXXXXXXXXXXSDRDQPGPHSALHYA----VLPGPHSEYLGFENELEPIIVVKKPL 173
E SD D+ G + + Y+ V P S++ + L I V +
Sbjct: 252 PENVSIGTLVIHPNASDLDE-GLNGDIIYSFSSDVSPDIKSKF--HMDPLSGAITVIGHM 308
Query: 174 DFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTF 233
DFE I + D+G PPL TL V V+D +D P+ T + + + +DA+ GT
Sbjct: 309 DFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVKEDAQLGTV 368
Query: 234 LTTSPGPISAADQDLGINAPLQYSSTGDHK-QLIVVNKDTGQVAATKQLIAELDPSVTIV 292
+ IS D D N + S T +L+ K+ + + L E + +V
Sbjct: 369 IAL----ISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSAYELV 424
Query: 293 LKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTT 352
+ A +P +A A + F Q +Y+ V E PG + T++
Sbjct: 425 VTARDGGSPSLWATARVSVEVADVNDNAPA-----FAQSEYTVFVKENNPPGCHIFTVSA 479
Query: 353 ----VPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTD 407
+N S ++ + +RS +++ +G+V + LD+E +QV D
Sbjct: 480 RDADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARD 539
Query: 408 S---ISNDTASINISVEDVNEWEPRFRHPQ 434
+ ++ + V D N+ P P+
Sbjct: 540 AGVPPLGSNVTLQVFVLDENDNAPALLTPR 569
Score = 70.9 bits (166), Expect = 2e-11
Identities = 88/317 (27%), Positives = 127/317 (40%), Gaps = 28/317 (8%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKN---LTLLRALDREE 67
+ ED +G++I +SV ++ G +T L +V KN L L RALDRE
Sbjct: 359 VKEDAQLGTVIALISVIDLDADANGQVTCSLTPH-VPFKLVSTYKNYYSLVLDRALDRES 417
Query: 68 KIGPSNVYVNVRCDRRRTTDPSF--VIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXX 125
+ + V R PS VSV V DVNDNAP + + Y V V E
Sbjct: 418 -VSAYELVVTARDGG----SPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGC 472
Query: 126 XXXXXXXSDRDQPGPHSALHYAVLP---GPHS--EYLGFENELEPIIVVKKPLDFETVNN 180
D D ++ + Y+++ G S Y+ E + ++ PLD E +
Sbjct: 473 HIFTVSARDADAQ-ENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQ-PLDHEELEL 530
Query: 181 FTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSP-- 238
++ +D G PPL S+ TLQV VLD +D P D A L +
Sbjct: 531 LQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLTPRMRGT--DGAVSEMVLRSVGAG 588
Query: 239 ---GPISAADQDLGINAPLQYS---STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIV 292
G + A D D G NA L Y T V TG+++ T+ L P ++
Sbjct: 589 VVVGKVRAVDADSGYNAWLSYELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLL 648
Query: 293 LKATQVDNPDRYALATL 309
+ P A AT+
Sbjct: 649 VLVKDHGEPALTATATV 665
>AC005609-5|AAC34313.1| 842|Homo sapiens KIAA0345-like 5 protein.
Length = 842
Score = 93.1 bits (221), Expect = 4e-18
Identities = 108/439 (24%), Positives = 177/439 (40%), Gaps = 23/439 (5%)
Query: 9 FFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAAVGIVPGSKN--LTLLRALDR 65
+ + E+ G+ +G ++ + G +L +L KG + +N L + +DR
Sbjct: 33 YSVPEEAEHGTFVGRIAQDLGLELAELVPRLFQLDSKGRGDLLEVNLQNGILFVNSRIDR 92
Query: 66 EEKIGPS---NVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXX 122
EE G S ++++ V DR P V V V V D+NDN P + + ++E+
Sbjct: 93 EELCGRSAECSIHLEVIVDR-----PLQVFHVDVEVKDINDNPPVFPATQKNLFIAESRP 147
Query: 123 XXXXXXXXXXSDRDQPGPHSALHYAVLPGPHS--EYLGFENELEPI-IVVKKPLDFETVN 179
SD D G ++ L Y + P + + +++P+ +V++K LD E
Sbjct: 148 LDSRFPLEGASDADI-GENALLTYRLSPNEYFFLDVPTSNQQVKPLGLVLRKLLDREETP 206
Query: 180 NFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPG 239
+ L D G P L L +TVLD +D P F YT LP++ GT L P
Sbjct: 207 ELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVKLPENVSIGT-LVIHP- 264
Query: 240 PISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVD 299
+A+D D G+N + YS + D I ++ +I +D + K V+
Sbjct: 265 --NASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMDFEESRAHKIP-VE 321
Query: 300 NPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEF 359
D+ Q T K S V E A G+V+ ++ + + +
Sbjct: 322 AVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVKEDAQLGTVIALISVIDLDADA 381
Query: 360 RESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSISND---TASI 416
F N ++L R+LD E+ S Y V D S TA +
Sbjct: 382 NGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSAYELVVTARDGGSPSLWATARV 441
Query: 417 NISVEDVNEWEPRFRHPQY 435
++ V DVN+ P F +Y
Sbjct: 442 SVEVADVNDNAPAFAQSEY 460
Score = 79.4 bits (187), Expect = 5e-14
Identities = 104/450 (23%), Positives = 181/450 (40%), Gaps = 40/450 (8%)
Query: 7 ESFFISEDTPIGSIIGTLSVNGDPSEDLGD---ITLRLQEKGAAVGIVPGSKN------L 57
++ FI+E P+ S + G D+G+ +T RL VP S L
Sbjct: 138 KNLFIAESRPLDS---RFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVKPLGL 194
Query: 58 TLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRV 117
L + LDREE +++ + + + + + + V D NDNAP ++ Y V++
Sbjct: 195 VLRKLLDREET---PELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVKL 251
Query: 118 SETXXXXXXXXXXXXSDRDQPGPHSALHYA----VLPGPHSEYLGFENELEPIIVVKKPL 173
E SD D+ G + + Y+ V P S++ + L I V +
Sbjct: 252 PENVSIGTLVIHPNASDLDE-GLNGDIIYSFSSDVSPDIKSKF--HMDPLSGAITVIGHM 308
Query: 174 DFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTF 233
DFE I + D+G PPL TL V V+D +D P+ T + + + +DA+ GT
Sbjct: 309 DFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVKEDAQLGTV 368
Query: 234 LTTSPGPISAADQDLGINAPLQYSSTGDHK-QLIVVNKDTGQVAATKQLIAELDPSVTIV 292
+ IS D D N + S T +L+ K+ + + L E + +V
Sbjct: 369 IAL----ISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSAYELV 424
Query: 293 LKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTT 352
+ A +P +A A + F Q +Y+ V E PG + T++
Sbjct: 425 VTARDGGSPSLWATARVSVEVADVNDNAPA-----FAQSEYTVFVKENNPPGCHIFTVSA 479
Query: 353 ----VPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTD 407
+N S ++ + +RS +++ +G+V + LD+E +QV D
Sbjct: 480 RDADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARD 539
Query: 408 S---ISNDTASINISVEDVNEWEPRFRHPQ 434
+ ++ + V D N+ P P+
Sbjct: 540 AGVPPLGSNVTLQVFVLDENDNAPALLTPR 569
Score = 70.9 bits (166), Expect = 2e-11
Identities = 88/317 (27%), Positives = 127/317 (40%), Gaps = 28/317 (8%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKN---LTLLRALDREE 67
+ ED +G++I +SV ++ G +T L +V KN L L RALDRE
Sbjct: 359 VKEDAQLGTVIALISVIDLDADANGQVTCSLTPH-VPFKLVSTYKNYYSLVLDRALDRES 417
Query: 68 KIGPSNVYVNVRCDRRRTTDPSF--VIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXX 125
+ + V R PS VSV V DVNDNAP + + Y V V E
Sbjct: 418 -VSAYELVVTARDGG----SPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGC 472
Query: 126 XXXXXXXSDRDQPGPHSALHYAVLP---GPHS--EYLGFENELEPIIVVKKPLDFETVNN 180
D D ++ + Y+++ G S Y+ E + ++ PLD E +
Sbjct: 473 HIFTVSARDADAQ-ENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQ-PLDHEELEL 530
Query: 181 FTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSP-- 238
++ +D G PPL S+ TLQV VLD +D P D A L +
Sbjct: 531 LQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLTPRMRGT--DGAVSEMVLRSVGAG 588
Query: 239 ---GPISAADQDLGINAPLQYS---STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIV 292
G + A D D G NA L Y T V TG+++ T+ L P ++
Sbjct: 589 VVVGKVRAVDADSGYNAWLSYELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLL 648
Query: 293 LKATQVDNPDRYALATL 309
+ P A AT+
Sbjct: 649 VLVKDHGEPALTATATV 665
>AB002343-1|BAA20803.2| 845|Homo sapiens KIAA0345 protein.
Length = 845
Score = 93.1 bits (221), Expect = 4e-18
Identities = 108/439 (24%), Positives = 177/439 (40%), Gaps = 23/439 (5%)
Query: 9 FFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAAVGIVPGSKN--LTLLRALDR 65
+ + E+ G+ +G ++ + G +L +L KG + +N L + +DR
Sbjct: 36 YSVPEEAEHGTFVGRIAQDLGLELAELVPRLFQLDSKGRGDLLEVNLQNGILFVNSRIDR 95
Query: 66 EEKIGPS---NVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXX 122
EE G S ++++ V DR P V V V V D+NDN P + + ++E+
Sbjct: 96 EELCGRSAECSIHLEVIVDR-----PLQVFHVDVEVKDINDNPPVFPATQKNLFIAESRP 150
Query: 123 XXXXXXXXXXSDRDQPGPHSALHYAVLPGPHS--EYLGFENELEPI-IVVKKPLDFETVN 179
SD D G ++ L Y + P + + +++P+ +V++K LD E
Sbjct: 151 LDSRFPLEGASDADI-GENALLTYRLSPNEYFFLDVPTSNQQVKPLGLVLRKLLDREETP 209
Query: 180 NFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPG 239
+ L D G P L L +TVLD +D P F YT LP++ GT L P
Sbjct: 210 ELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVKLPENVSIGT-LVIHP- 267
Query: 240 PISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVD 299
+A+D D G+N + YS + D I ++ +I +D + K V+
Sbjct: 268 --NASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMDFEESRAHKIP-VE 324
Query: 300 NPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEF 359
D+ Q T K S V E A G+V+ ++ + + +
Sbjct: 325 AVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVKEDAQLGTVIALISVIDLDADA 384
Query: 360 RESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSISND---TASI 416
F N ++L R+LD E+ S Y V D S TA +
Sbjct: 385 NGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSAYELVVTARDGGSPSLWATARV 444
Query: 417 NISVEDVNEWEPRFRHPQY 435
++ V DVN+ P F +Y
Sbjct: 445 SVEVADVNDNAPAFAQSEY 463
Score = 79.4 bits (187), Expect = 5e-14
Identities = 104/450 (23%), Positives = 181/450 (40%), Gaps = 40/450 (8%)
Query: 7 ESFFISEDTPIGSIIGTLSVNGDPSEDLGD---ITLRLQEKGAAVGIVPGSKN------L 57
++ FI+E P+ S + G D+G+ +T RL VP S L
Sbjct: 141 KNLFIAESRPLDS---RFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVKPLGL 197
Query: 58 TLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRV 117
L + LDREE +++ + + + + + + V D NDNAP ++ Y V++
Sbjct: 198 VLRKLLDREET---PELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVKL 254
Query: 118 SETXXXXXXXXXXXXSDRDQPGPHSALHYA----VLPGPHSEYLGFENELEPIIVVKKPL 173
E SD D+ G + + Y+ V P S++ + L I V +
Sbjct: 255 PENVSIGTLVIHPNASDLDE-GLNGDIIYSFSSDVSPDIKSKF--HMDPLSGAITVIGHM 311
Query: 174 DFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTF 233
DFE I + D+G PPL TL V V+D +D P+ T + + + +DA+ GT
Sbjct: 312 DFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVKEDAQLGTV 371
Query: 234 LTTSPGPISAADQDLGINAPLQYSSTGDHK-QLIVVNKDTGQVAATKQLIAELDPSVTIV 292
+ IS D D N + S T +L+ K+ + + L E + +V
Sbjct: 372 IAL----ISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSAYELV 427
Query: 293 LKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTT 352
+ A +P +A A + F Q +Y+ V E PG + T++
Sbjct: 428 VTARDGGSPSLWATARVSVEVADVNDNAPA-----FAQSEYTVFVKENNPPGCHIFTVSA 482
Query: 353 ----VPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTD 407
+N S ++ + +RS +++ +G+V + LD+E +QV D
Sbjct: 483 RDADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARD 542
Query: 408 S---ISNDTASINISVEDVNEWEPRFRHPQ 434
+ ++ + V D N+ P P+
Sbjct: 543 AGVPPLGSNVTLQVFVLDENDNAPALLTPR 572
Score = 70.9 bits (166), Expect = 2e-11
Identities = 88/317 (27%), Positives = 127/317 (40%), Gaps = 28/317 (8%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKN---LTLLRALDREE 67
+ ED +G++I +SV ++ G +T L +V KN L L RALDRE
Sbjct: 362 VKEDAQLGTVIALISVIDLDADANGQVTCSLTPH-VPFKLVSTYKNYYSLVLDRALDRES 420
Query: 68 KIGPSNVYVNVRCDRRRTTDPSF--VIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXX 125
+ + V R PS VSV V DVNDNAP + + Y V V E
Sbjct: 421 -VSAYELVVTARDGG----SPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGC 475
Query: 126 XXXXXXXSDRDQPGPHSALHYAVLP---GPHS--EYLGFENELEPIIVVKKPLDFETVNN 180
D D ++ + Y+++ G S Y+ E + ++ PLD E +
Sbjct: 476 HIFTVSARDADAQ-ENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQ-PLDHEELEL 533
Query: 181 FTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSP-- 238
++ +D G PPL S+ TLQV VLD +D P D A L +
Sbjct: 534 LQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLTPRMRGT--DGAVSEMVLRSVGAG 591
Query: 239 ---GPISAADQDLGINAPLQYS---STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIV 292
G + A D D G NA L Y T V TG+++ T+ L P ++
Sbjct: 592 VVVGKVRAVDADSGYNAWLSYELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLL 651
Query: 293 LKATQVDNPDRYALATL 309
+ P A AT+
Sbjct: 652 VLVKDHGEPALTATATV 668
>BC112083-1|AAI12084.1| 878|Homo sapiens protocadherin gamma
subfamily C, 5, isoform 2 precursor protein.
Length = 878
Score = 92.7 bits (220), Expect = 5e-18
Identities = 85/312 (27%), Positives = 137/312 (43%), Gaps = 25/312 (8%)
Query: 11 ISEDTPIGSIIGTLSV-------NGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRAL 63
I E+ PIG+++ L+ NG GD T G+ P S + +L +
Sbjct: 251 IPENAPIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRN--LFGLDPSSGAIHVLGPI 308
Query: 64 DREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXX 123
D EE ++ R + + VI V V DVNDNAP+ A A V E+
Sbjct: 309 DFEESRF-YEIHARARDQGQPAMEGHCVIQVDVG--DVNDNAPEVLLASLANPVLESTPV 365
Query: 124 XXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTI 183
DRD G + + + P + EN ++ +PLD E +++ I
Sbjct: 366 GTVVGLFNVRDRDS-GRNGEVSLDISPDLPFQIKPSENHYS--LLTSQPLDREATSHYII 422
Query: 184 KLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISA 243
+L D GSP L+ T+++ + D +D P+F + YTA + ++ G+ L T ++A
Sbjct: 423 ELLASDAGSPSLHKHLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGSLLCT----VAA 478
Query: 244 ADQDLGINAPLQYSSTGDHKQ------LIVVNKDTGQVAATKQLIAELDPSVTIVLKATQ 297
+D D G NA L YS G+ Q + VN + G++ A + EL + IV+
Sbjct: 479 SDPDTGDNARLTYSIVGNQVQGAPASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRD 538
Query: 298 VDNPDRYALATL 309
+P +A +L
Sbjct: 539 SGSPPLHANTSL 550
Score = 92.3 bits (219), Expect = 7e-18
Identities = 81/314 (25%), Positives = 144/314 (45%), Gaps = 25/314 (7%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRA--LDREEK 68
+ E TP+G+++G +V S G+++L + I P + +LL + LDRE
Sbjct: 359 VLESTPVGTVVGLFNVRDRDSGRNGEVSLDISPD-LPFQIKPSENHYSLLTSQPLDRE-- 415
Query: 69 IGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXX 128
S+ + + + + + + + DVNDNAP++ Y + E
Sbjct: 416 -ATSHYIIELLASDAGSPSLHKHLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGSLLC 474
Query: 129 XXXXSDRDQPGPHSALHYAVLPG-----PHSEYLGFENELEPIIVVKKPLDFETVNNFTI 183
SD D G ++ L Y+++ P S ++ + N + I ++ D+E + I
Sbjct: 475 TVAASDPDT-GDNARLTYSIVGNQVQGAPASSFV-YVNPEDGRIFAQRTFDYELLQMLQI 532
Query: 184 KLRVQDQGSPPLYSDTTLQVTVLDADDQ-----NPKFTYEHYT-ALLPDDAEEGTFLTTS 237
+ V+D GSPPL+++T+L V VLD +D +P+ +EH LP A G+ +T
Sbjct: 533 VVGVRDSGSPPLHANTSLHVFVLDENDNAPAVLHPRPGWEHSAPQRLPRSAPPGSLVT-- 590
Query: 238 PGPISAADQDLGINAPLQYS--STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKA 295
++A D D G NA L YS L +V+ TG+V + L+ + + +V+
Sbjct: 591 --KVTAVDADAGHNAWLSYSLLPQSTAPGLFLVSTHTGEVRTARALLEDDSDTQQVVVLV 648
Query: 296 TQVDNPDRYALATL 309
+P + AT+
Sbjct: 649 RDNGDPSLSSTATV 662
Score = 83.4 bits (197), Expect = 3e-15
Identities = 108/447 (24%), Positives = 173/447 (38%), Gaps = 29/447 (6%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
+SV V D+NDNAP ++ + V + E +D D+ G + L Y+ G H
Sbjct: 228 ISVIVLDINDNAPTFQSSVLRVGIPENAPIGTLLLRLNATDPDE-GTNGQLDYSF--GDH 284
Query: 154 -SEYLGFENELEP---IIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDAD 209
SE + L+P I V P+DFE + I R +DQG P + +QV V D +
Sbjct: 285 TSEAVRNLFGLDPSSGAIHVLGPIDFEESRFYEIHARARDQGQPAMEGHCVIQVDVGDVN 344
Query: 210 DQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVN 269
D P E A L + E T + T G + D+D G N + + D I +
Sbjct: 345 DNAP----EVLLASLANPVLESTPVGTVVGLFNVRDRDSGRNGEVSLDISPDLPFQIKPS 400
Query: 270 KDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFT 329
++ + ++ L E I L A+ +P + T+ +F
Sbjct: 401 ENHYSLLTSQPLDREATSHYIIELLASDAGSPSLHKHLTIRLNISDVNDNAP-----RFN 455
Query: 330 QKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDR---SFLDKFAINNA--GE 384
Q+ Y+ + E PGS+L T+ +T V ++ + F N G
Sbjct: 456 QQLYTAYILENRPPGSLLCTVAASDPDTGDNARLTYSIVGNQVQGAPASSFVYVNPEDGR 515
Query: 385 VILRRSLDYETTSNYFYQVMVTDSIS---NDTASINISVEDVNEWEPRFRHPQYEFEXXX 441
+ +R+ DYE V V DS S + S+++ V D N+ P HP+ +E
Sbjct: 516 IFAQRTFDYELLQMLQIVVGVRDSGSPPLHANTSLHVFVLDENDNAPAVLHPRPGWEHSA 575
Query: 442 XXXXXXXXXXXXXXXXXVAHDGDAG---TLALSLAGQHAR--MFYINASGDLFLREEAIG 496
A D DAG L+ SL Q +F ++ A+
Sbjct: 576 PQRLPRSAPPGSLVTKVTAVDADAGHNAWLSYSLLPQSTAPGLFLVSTHTGEVRTARALL 635
Query: 497 NLNSSSLHLVATAIDSGIPPRQTSVPV 523
+S + +V D+G P ++ V
Sbjct: 636 EDDSDTQQVVVLVRDNGDPSLSSTATV 662
Score = 81.0 bits (191), Expect = 2e-14
Identities = 102/443 (23%), Positives = 177/443 (39%), Gaps = 32/443 (7%)
Query: 9 FFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRL--QEKGAAVGIVPGSKNLTLLRALDR 65
+ + E++ G+++G ++ + G DL L+L +E G + S L + + +DR
Sbjct: 33 YSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLGSEENGRYFSLSLMSGALAVNQKIDR 92
Query: 66 EEKIGPS-NVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXX 124
E G S + + V+ T P +I V V + D+NDN+P + +R+SE+
Sbjct: 93 ESLCGASTSCLLPVQVV---TEHPLELIRVEVEILDLNDNSPSFATPEREMRISESAASG 149
Query: 125 XXXXXXXXSDRDQPGPHSALHYAVLPGPHSEY---LGFENELEPIIVVKKPLDFETVNNF 181
D D G ++ Y + P H + + P +V+++ LD E
Sbjct: 150 ARFPLDSAQDPDV-GTNTVSFYTLSPNSHFSLNVKTLKDGKPFPELVLEQQLDREAQARH 208
Query: 182 TIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPI 241
+ L D G+P T + V VLD +D P F +P++A GT L +
Sbjct: 209 QLVLTAVDGGTPARSGTTLISVIVLDINDNAPTFQSSVLRVGIPENAPIGTLLLR----L 264
Query: 242 SAADQDLGINAPLQYSSTGDH-----KQLIVVNKDTGQVAATKQLIAELDPSVTIVLKAT 296
+A D D G N L Y S GDH + L ++ +G + + E I +A
Sbjct: 265 NATDPDEGTNGQLDY-SFGDHTSEAVRNLFGLDPSSGAIHVLGPIDFEESRFYEIHARAR 323
Query: 297 QVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQN 356
P + +T P ++ L V
Sbjct: 324 DQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVLEST------PVGTVVGLFNVRDR 377
Query: 357 TEFRESPLQFYVS-DRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSIS---ND 412
R + +S D F K + N+ ++ + LD E TS+Y +++ +D+ S +
Sbjct: 378 DSGRNGEVSLDISPDLPFQIKPSENHY-SLLTSQPLDREATSHYIIELLASDAGSPSLHK 436
Query: 413 TASINISVEDVNEWEPRFRHPQY 435
+I +++ DVN+ PRF Y
Sbjct: 437 HLTIRLNISDVNDNAPRFNQQLY 459
>BC112081-1|AAI12082.1| 878|Homo sapiens protocadherin gamma
subfamily C, 5, isoform 2 precursor protein.
Length = 878
Score = 92.7 bits (220), Expect = 5e-18
Identities = 85/312 (27%), Positives = 137/312 (43%), Gaps = 25/312 (8%)
Query: 11 ISEDTPIGSIIGTLSV-------NGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRAL 63
I E+ PIG+++ L+ NG GD T G+ P S + +L +
Sbjct: 251 IPENAPIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRN--LFGLDPSSGAIHVLGPI 308
Query: 64 DREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXX 123
D EE ++ R + + VI V V DVNDNAP+ A A V E+
Sbjct: 309 DFEESRF-YEIHARARDQGQPAMEGHCVIQVDVG--DVNDNAPEVLLASLANPVLESTPV 365
Query: 124 XXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTI 183
DRD G + + + P + EN ++ +PLD E +++ I
Sbjct: 366 GTVVGLFNVRDRDS-GRNGEVSLDISPDLPFQIKPSENHYS--LLTSQPLDREATSHYII 422
Query: 184 KLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISA 243
+L D GSP L+ T+++ + D +D P+F + YTA + ++ G+ L T ++A
Sbjct: 423 ELLASDAGSPSLHKHLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGSLLCT----VAA 478
Query: 244 ADQDLGINAPLQYSSTGDHKQ------LIVVNKDTGQVAATKQLIAELDPSVTIVLKATQ 297
+D D G NA L YS G+ Q + VN + G++ A + EL + IV+
Sbjct: 479 SDPDTGDNARLTYSIVGNQVQGAPASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRD 538
Query: 298 VDNPDRYALATL 309
+P +A +L
Sbjct: 539 SGSPPLHANTSL 550
Score = 92.3 bits (219), Expect = 7e-18
Identities = 81/314 (25%), Positives = 144/314 (45%), Gaps = 25/314 (7%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRA--LDREEK 68
+ E TP+G+++G +V S G+++L + I P + +LL + LDRE
Sbjct: 359 VLESTPVGTVVGLFNVRDRDSGRNGEVSLDISPD-LPFQIKPSENHYSLLTSQPLDRE-- 415
Query: 69 IGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXX 128
S+ + + + + + + + DVNDNAP++ Y + E
Sbjct: 416 -ATSHYIIELLASDAGSPSLHKHLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGSLLC 474
Query: 129 XXXXSDRDQPGPHSALHYAVLPG-----PHSEYLGFENELEPIIVVKKPLDFETVNNFTI 183
SD D G ++ L Y+++ P S ++ + N + I ++ D+E + I
Sbjct: 475 TVAASDPDT-GDNARLTYSIVGNQVQGAPASSFV-YVNPEDGRIFAQRTFDYELLQMLQI 532
Query: 184 KLRVQDQGSPPLYSDTTLQVTVLDADDQ-----NPKFTYEHYT-ALLPDDAEEGTFLTTS 237
+ V+D GSPPL+++T+L V VLD +D +P+ +EH LP A G+ +T
Sbjct: 533 VVGVRDSGSPPLHANTSLHVFVLDENDNAPAVLHPRPGWEHSAPQRLPRSAPPGSLVT-- 590
Query: 238 PGPISAADQDLGINAPLQYS--STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKA 295
++A D D G NA L YS L +V+ TG+V + L+ + + +V+
Sbjct: 591 --KVTAVDADAGHNAWLSYSLLPQSTAPGLFLVSTHTGEVRTARALLEDDSDTQQVVVLV 648
Query: 296 TQVDNPDRYALATL 309
+P + AT+
Sbjct: 649 RDNGDPSLSSTATV 662
Score = 83.4 bits (197), Expect = 3e-15
Identities = 108/447 (24%), Positives = 173/447 (38%), Gaps = 29/447 (6%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
+SV V D+NDNAP ++ + V + E +D D+ G + L Y+ G H
Sbjct: 228 ISVIVLDINDNAPTFQSSVLRVGIPENAPIGTLLLRLNATDPDE-GTNGQLDYSF--GDH 284
Query: 154 -SEYLGFENELEP---IIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDAD 209
SE + L+P I V P+DFE + I R +DQG P + +QV V D +
Sbjct: 285 TSEAVRNLFGLDPSSGAIHVLGPIDFEESRFYEIHARARDQGQPAMEGHCVIQVDVGDVN 344
Query: 210 DQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVN 269
D P E A L + E T + T G + D+D G N + + D I +
Sbjct: 345 DNAP----EVLLASLANPVLESTPVGTVVGLFNVRDRDSGRNGEVSLDISPDLPFQIKPS 400
Query: 270 KDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFT 329
++ + ++ L E I L A+ +P + T+ +F
Sbjct: 401 ENHYSLLTSQPLDREATSHYIIELLASDAGSPSLHKHLTIRLNISDVNDNAP-----RFN 455
Query: 330 QKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDR---SFLDKFAINNA--GE 384
Q+ Y+ + E PGS+L T+ +T V ++ + F N G
Sbjct: 456 QQLYTAYILENRPPGSLLCTVAASDPDTGDNARLTYSIVGNQVQGAPASSFVYVNPEDGR 515
Query: 385 VILRRSLDYETTSNYFYQVMVTDSIS---NDTASINISVEDVNEWEPRFRHPQYEFEXXX 441
+ +R+ DYE V V DS S + S+++ V D N+ P HP+ +E
Sbjct: 516 IFAQRTFDYELLQMLQIVVGVRDSGSPPLHANTSLHVFVLDENDNAPAVLHPRPGWEHSA 575
Query: 442 XXXXXXXXXXXXXXXXXVAHDGDAG---TLALSLAGQHAR--MFYINASGDLFLREEAIG 496
A D DAG L+ SL Q +F ++ A+
Sbjct: 576 PQRLPRSAPPGSLVTKVTAVDADAGHNAWLSYSLLPQSTAPGLFLVSTHTGEVRTARALL 635
Query: 497 NLNSSSLHLVATAIDSGIPPRQTSVPV 523
+S + +V D+G P ++ V
Sbjct: 636 EDDSDTQQVVVLVRDNGDPSLSSTATV 662
Score = 81.0 bits (191), Expect = 2e-14
Identities = 102/443 (23%), Positives = 177/443 (39%), Gaps = 32/443 (7%)
Query: 9 FFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRL--QEKGAAVGIVPGSKNLTLLRALDR 65
+ + E++ G+++G ++ + G DL L+L +E G + S L + + +DR
Sbjct: 33 YSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLGSEENGRYFSLSLMSGALAVNQKIDR 92
Query: 66 EEKIGPS-NVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXX 124
E G S + + V+ T P +I V V + D+NDN+P + +R+SE+
Sbjct: 93 ESLCGASTSCLLPVQVV---TEHPLELIRVEVEILDLNDNSPSFATPEREMRISESAASG 149
Query: 125 XXXXXXXXSDRDQPGPHSALHYAVLPGPHSEY---LGFENELEPIIVVKKPLDFETVNNF 181
D D G ++ Y + P H + + P +V+++ LD E
Sbjct: 150 ARFPLDSAQDPDV-GTNTVSFYTLSPNSHFSLNVKTLKDGKPFPELVLEQQLDREAQARH 208
Query: 182 TIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPI 241
+ L D G+P T + V VLD +D P F +P++A GT L +
Sbjct: 209 QLVLTAVDGGTPARSGTTLISVIVLDINDNAPTFQSSVLRVGIPENAPIGTLLLR----L 264
Query: 242 SAADQDLGINAPLQYSSTGDH-----KQLIVVNKDTGQVAATKQLIAELDPSVTIVLKAT 296
+A D D G N L Y S GDH + L ++ +G + + E I +A
Sbjct: 265 NATDPDEGTNGQLDY-SFGDHTSEAVRNLFGLDPSSGAIHVLGPIDFEESRFYEIHARAR 323
Query: 297 QVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQN 356
P + +T P ++ L V
Sbjct: 324 DQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVLEST------PVGTVVGLFNVRDR 377
Query: 357 TEFRESPLQFYVS-DRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSIS---ND 412
R + +S D F K + N+ ++ + LD E TS+Y +++ +D+ S +
Sbjct: 378 DSGRNGEVSLDISPDLPFQIKPSENHY-SLLTSQPLDREATSHYIIELLASDAGSPSLHK 436
Query: 413 TASINISVEDVNEWEPRFRHPQY 435
+I +++ DVN+ PRF Y
Sbjct: 437 HLTIRLNISDVNDNAPRFNQQLY 459
>AY563166-1|AAT72166.1| 1079|Homo sapiens cadherin 23 isoform B2
protein.
Length = 1079
Score = 92.7 bits (220), Expect = 5e-18
Identities = 101/454 (22%), Positives = 197/454 (43%), Gaps = 42/454 (9%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEK-- 68
+ ED P+G+II T++ S + I L + + I P + ++ +L +LDRE+K
Sbjct: 171 VFEDVPVGTIILTVTATDADSGNFALIEYSLGDGESKFAINPTTGDIYVLSSLDREKKDH 230
Query: 69 -----IGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXX 123
+ N +V +RR + + V ++V DVND PQ+ ++ V E
Sbjct: 231 YILTALAKDNP-GDVASNRRENS-----VQVVIQVLDVNDCRPQFSKPQFSTSVYENEPA 284
Query: 124 XXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTI 183
+D+D+ GP+ L Y+ L GP E + + ++ ++PL ++ F++
Sbjct: 285 GTSVITMMATDQDE-GPNGELTYS-LEGPGVEAFHVDMD-SGLVTTQRPL--QSYEKFSL 339
Query: 184 KLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISA 243
+ D G PPL+ T L V V+D +D P F +L E L ++ + A
Sbjct: 340 TVVATDGGEPPLWGTTMLLVEVIDVNDNRPVFVRPPNGTIL--HIREEIPLRSNVYEVYA 397
Query: 244 ADQDLGINAPLQYS--STGDHK--QLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVD 299
D+D G+N ++YS T ++ + +++ +G + ++L E +++L A+ +
Sbjct: 398 TDKDEGLNGAVRYSFLKTAGNRDWEFFIIDPISGLIQTAQRLDRESQAVYSLILVASDLG 457
Query: 300 NPDRY-ALATLXXXXXXXXXXXXXXXXLQFTQKQYS-TTVSEGASPGSVLLTLTTVPQNT 357
P Y + L QY TV E + G+++ +T
Sbjct: 458 QPVPYETMQPLQVALEDIDDNEPLFVRPPKGSPQYQLLTVPEHSPRGTLVGNVTGAVDAD 517
Query: 358 EFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVT----------- 406
E + + ++++ + F + G +++ R LD E + + + V +
Sbjct: 518 EGPNAIVYYFIAAGNEEKNFHLQPDGCLLVLRDLDREREAIFSFIVKASSNRSWTPPRGP 577
Query: 407 ----DSISNDT-ASINISVEDVNEWEPRFRHPQY 435
D +++ T + + +ED+N+ PRF +Y
Sbjct: 578 SPTLDLVADLTLQEVRVVLEDINDQPPRFTKAEY 611
Score = 91.5 bits (217), Expect = 1e-17
Identities = 87/348 (25%), Positives = 151/348 (43%), Gaps = 20/348 (5%)
Query: 94 VSVRVWDVNDNAPQWE--GAPYAV-RVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLP 150
++V V DVNDN PQ++ G Y + R+ E D D+ G + + Y +L
Sbjct: 39 LTVNVLDVNDNTPQFKPFGITYYMERILEGATPGTTLIAVAAVDPDK-GLNGLVTYTLLD 97
Query: 151 GPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADD 210
Y+ E+ ++ + +D+E V+ +R D GSPP ++ + + ++D +D
Sbjct: 98 LVPPGYVQLEDSSAGKVIANRTVDYEEVHWLNFTVRASDNGSPPRAAEIPVYLEIVDIND 157
Query: 211 QNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNK 270
NP F Y + +D GT + T ++A D D G A ++Y S GD + +N
Sbjct: 158 NNPIFDQPSYQEAVFEDVPVGTIILT----VTATDADSGNFALIEY-SLGDGESKFAINP 212
Query: 271 DTGQVAATKQLIAELDPSVTIVLKATQVDNP-DRYALATLXXXXXXXXXXXXXXXXLQFT 329
TG + L + + +L A DNP D + QF+
Sbjct: 213 TTGDIYVLSSL--DREKKDHYILTALAKDNPGDVASNRRENSVQVVIQVLDVNDCRPQFS 270
Query: 330 QKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILR 388
+ Q+ST+V E G+ ++T+ Q+ E L Y + ++ F ++ ++G V +
Sbjct: 271 KPQFSTSVYENEPAGTSVITMMATDQD-EGPNGELT-YSLEGPGVEAFHVDMDSGLVTTQ 328
Query: 389 RSLDYETTSNYFYQVMVTDSISN---DTASINISVEDVNEWEPRFRHP 433
R L ++ + V+ TD T + + V DVN+ P F P
Sbjct: 329 RPL--QSYEKFSLTVVATDGGEPPLWGTTMLLVEVIDVNDNRPVFVRP 374
Score = 74.5 bits (175), Expect = 1e-12
Identities = 90/367 (24%), Positives = 148/367 (40%), Gaps = 35/367 (9%)
Query: 168 VVKKPLDFETVNNFTIKLRVQDQGSP-PLYS----DTTLQVTVLDADDQNPKFT---YEH 219
+VK P++ E V + + L V D S P S + L V VLD +D P+F +
Sbjct: 1 MVKSPMNRELVATYEVTLSVIDNASDLPERSVSVPNAKLTVNVLDVNDNTPQFKPFGITY 60
Query: 220 YTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDT--GQVAA 277
Y + + A GT L ++A D D G+N + Y+ V +D+ G+V A
Sbjct: 61 YMERILEGATPGTTLIA----VAAVDPDKGLNGLVTYTLLDLVPPGYVQLEDSSAGKVIA 116
Query: 278 TKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTV 337
+ + E + ++A+ +P R A + F Q Y V
Sbjct: 117 NRTVDYEEVHWLNFTVRASDNGSPPRAAEIPVYLEIVDINDNNPI-----FDQPSYQEAV 171
Query: 338 SEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETT 396
E G+++LT+T ++ + +++ + D KFAIN G++ + SLD E
Sbjct: 172 FEDVPVGTIILTVTATDADSG-NFALIEYSLGDGE--SKFAINPTTGDIYVLSSLDREKK 228
Query: 397 SNYFYQVMVTDS----ISN---DTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXX 449
+Y + D+ SN ++ + I V DVN+ P+F PQ+
Sbjct: 229 DHYILTALAKDNPGDVASNRRENSVQVVIQVLDVNDCRPQFSKPQFSTSVYENEPAGTSV 288
Query: 450 XXXXXXXXXVAHDGDAGTLALSLAGQHARMFYINASGDLFLREEAIGNLNSSSLHLVATA 509
+G G L SL G F+++ L + + + SL +VAT
Sbjct: 289 ITMMATDQD---EGPNGELTYSLEGPGVEAFHVDMDSGLVTTQRPLQSYEKFSLTVVAT- 344
Query: 510 IDSGIPP 516
D G PP
Sbjct: 345 -DGGEPP 350
Score = 56.0 bits (129), Expect = 6e-07
Identities = 52/205 (25%), Positives = 89/205 (43%), Gaps = 12/205 (5%)
Query: 92 IPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPG 151
IPV + + D+NDN P ++ Y V E +D D G + + Y++ G
Sbjct: 146 IPVYLEIVDINDNNPIFDQPSYQEAVFEDVPVGTIILTVTATDADS-GNFALIEYSLGDG 204
Query: 152 PHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQ----GSPPLYSDTTLQVTVLD 207
S++ N I V LD E +++ + +D S + + + VLD
Sbjct: 205 -ESKFA--INPTTGDIYVLSSLDREKKDHYILTALAKDNPGDVASNRRENSVQVVIQVLD 261
Query: 208 ADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIV 267
+D P+F+ ++ + ++ GT + T + A DQD G N L YS G +
Sbjct: 262 VNDCRPQFSKPQFSTSVYENEPAGTSVIT----MMATDQDEGPNGELTYSLEGPGVEAFH 317
Query: 268 VNKDTGQVAATKQLIAELDPSVTIV 292
V+ D+G V + L + S+T+V
Sbjct: 318 VDMDSGLVTTQRPLQSYEKFSLTVV 342
Score = 54.0 bits (124), Expect = 2e-06
Identities = 66/247 (26%), Positives = 110/247 (44%), Gaps = 29/247 (11%)
Query: 50 IVPGSKNLTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQW- 108
I P S + + LDRE + S + V D + + P+ V + D++DN P +
Sbjct: 426 IDPISGLIQTAQRLDRESQAVYSLILV--ASDLGQPVPYETMQPLQVALEDIDDNEPLFV 483
Query: 109 ---EGAPY--AVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENEL 163
+G+P + V E + GP++ ++Y + G +E F +
Sbjct: 484 RPPKGSPQYQLLTVPEHSPRGTLVGNVTGAVDADEGPNAIVYYFIAAG--NEEKNFHLQP 541
Query: 164 EPIIVVKKPLDFE--TVNNFTIKLRVQDQGSPP--------LYSDTTLQ---VTVLDADD 210
+ ++V + LD E + +F +K +PP L +D TLQ V + D +D
Sbjct: 542 DGCLLVLRDLDREREAIFSFIVKASSNRSWTPPRGPSPTLDLVADLTLQEVRVVLEDIND 601
Query: 211 QNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDH--KQLIVV 268
Q P+FT YTA + DA+ G+ L + A D D+G N+ + YS H + L
Sbjct: 602 QPPRFTKAEYTAGVATDAKVGSELI----QVLALDADIGNNSLVFYSILAIHYFRALAND 657
Query: 269 NKDTGQV 275
++D GQV
Sbjct: 658 SEDVGQV 664
>AY563165-1|AAT72165.1| 1114|Homo sapiens cadherin 23 isoform B1
protein.
Length = 1114
Score = 92.7 bits (220), Expect = 5e-18
Identities = 101/454 (22%), Positives = 197/454 (43%), Gaps = 42/454 (9%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEK-- 68
+ ED P+G+II T++ S + I L + + I P + ++ +L +LDRE+K
Sbjct: 171 VFEDVPVGTIILTVTATDADSGNFALIEYSLGDGESKFAINPTTGDIYVLSSLDREKKDH 230
Query: 69 -----IGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXX 123
+ N +V +RR + + V ++V DVND PQ+ ++ V E
Sbjct: 231 YILTALAKDNP-GDVASNRRENS-----VQVVIQVLDVNDCRPQFSKPQFSTSVYENEPA 284
Query: 124 XXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTI 183
+D+D+ GP+ L Y+ L GP E + + ++ ++PL ++ F++
Sbjct: 285 GTSVITMMATDQDE-GPNGELTYS-LEGPGVEAFHVDMD-SGLVTTQRPL--QSYEKFSL 339
Query: 184 KLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISA 243
+ D G PPL+ T L V V+D +D P F +L E L ++ + A
Sbjct: 340 TVVATDGGEPPLWGTTMLLVEVIDVNDNRPVFVRPPNGTIL--HIREEIPLRSNVYEVYA 397
Query: 244 ADQDLGINAPLQYS--STGDHK--QLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVD 299
D+D G+N ++YS T ++ + +++ +G + ++L E +++L A+ +
Sbjct: 398 TDKDEGLNGAVRYSFLKTAGNRDWEFFIIDPISGLIQTAQRLDRESQAVYSLILVASDLG 457
Query: 300 NPDRY-ALATLXXXXXXXXXXXXXXXXLQFTQKQYS-TTVSEGASPGSVLLTLTTVPQNT 357
P Y + L QY TV E + G+++ +T
Sbjct: 458 QPVPYETMQPLQVALEDIDDNEPLFVRPPKGSPQYQLLTVPEHSPRGTLVGNVTGAVDAD 517
Query: 358 EFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVT----------- 406
E + + ++++ + F + G +++ R LD E + + + V +
Sbjct: 518 EGPNAIVYYFIAAGNEEKNFHLQPDGCLLVLRDLDREREAIFSFIVKASSNRSWTPPRGP 577
Query: 407 ----DSISNDT-ASINISVEDVNEWEPRFRHPQY 435
D +++ T + + +ED+N+ PRF +Y
Sbjct: 578 SPTLDLVADLTLQEVRVVLEDINDQPPRFTKAEY 611
Score = 91.5 bits (217), Expect = 1e-17
Identities = 87/348 (25%), Positives = 151/348 (43%), Gaps = 20/348 (5%)
Query: 94 VSVRVWDVNDNAPQWE--GAPYAV-RVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLP 150
++V V DVNDN PQ++ G Y + R+ E D D+ G + + Y +L
Sbjct: 39 LTVNVLDVNDNTPQFKPFGITYYMERILEGATPGTTLIAVAAVDPDK-GLNGLVTYTLLD 97
Query: 151 GPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADD 210
Y+ E+ ++ + +D+E V+ +R D GSPP ++ + + ++D +D
Sbjct: 98 LVPPGYVQLEDSSAGKVIANRTVDYEEVHWLNFTVRASDNGSPPRAAEIPVYLEIVDIND 157
Query: 211 QNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNK 270
NP F Y + +D GT + T ++A D D G A ++Y S GD + +N
Sbjct: 158 NNPIFDQPSYQEAVFEDVPVGTIILT----VTATDADSGNFALIEY-SLGDGESKFAINP 212
Query: 271 DTGQVAATKQLIAELDPSVTIVLKATQVDNP-DRYALATLXXXXXXXXXXXXXXXXLQFT 329
TG + L + + +L A DNP D + QF+
Sbjct: 213 TTGDIYVLSSL--DREKKDHYILTALAKDNPGDVASNRRENSVQVVIQVLDVNDCRPQFS 270
Query: 330 QKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILR 388
+ Q+ST+V E G+ ++T+ Q+ E L Y + ++ F ++ ++G V +
Sbjct: 271 KPQFSTSVYENEPAGTSVITMMATDQD-EGPNGELT-YSLEGPGVEAFHVDMDSGLVTTQ 328
Query: 389 RSLDYETTSNYFYQVMVTDSISN---DTASINISVEDVNEWEPRFRHP 433
R L ++ + V+ TD T + + V DVN+ P F P
Sbjct: 329 RPL--QSYEKFSLTVVATDGGEPPLWGTTMLLVEVIDVNDNRPVFVRP 374
Score = 74.5 bits (175), Expect = 1e-12
Identities = 90/367 (24%), Positives = 148/367 (40%), Gaps = 35/367 (9%)
Query: 168 VVKKPLDFETVNNFTIKLRVQDQGSP-PLYS----DTTLQVTVLDADDQNPKFT---YEH 219
+VK P++ E V + + L V D S P S + L V VLD +D P+F +
Sbjct: 1 MVKSPMNRELVATYEVTLSVIDNASDLPERSVSVPNAKLTVNVLDVNDNTPQFKPFGITY 60
Query: 220 YTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDT--GQVAA 277
Y + + A GT L ++A D D G+N + Y+ V +D+ G+V A
Sbjct: 61 YMERILEGATPGTTLIA----VAAVDPDKGLNGLVTYTLLDLVPPGYVQLEDSSAGKVIA 116
Query: 278 TKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTV 337
+ + E + ++A+ +P R A + F Q Y V
Sbjct: 117 NRTVDYEEVHWLNFTVRASDNGSPPRAAEIPVYLEIVDINDNNPI-----FDQPSYQEAV 171
Query: 338 SEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETT 396
E G+++LT+T ++ + +++ + D KFAIN G++ + SLD E
Sbjct: 172 FEDVPVGTIILTVTATDADSG-NFALIEYSLGDGE--SKFAINPTTGDIYVLSSLDREKK 228
Query: 397 SNYFYQVMVTDS----ISN---DTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXX 449
+Y + D+ SN ++ + I V DVN+ P+F PQ+
Sbjct: 229 DHYILTALAKDNPGDVASNRRENSVQVVIQVLDVNDCRPQFSKPQFSTSVYENEPAGTSV 288
Query: 450 XXXXXXXXXVAHDGDAGTLALSLAGQHARMFYINASGDLFLREEAIGNLNSSSLHLVATA 509
+G G L SL G F+++ L + + + SL +VAT
Sbjct: 289 ITMMATDQD---EGPNGELTYSLEGPGVEAFHVDMDSGLVTTQRPLQSYEKFSLTVVAT- 344
Query: 510 IDSGIPP 516
D G PP
Sbjct: 345 -DGGEPP 350
Score = 56.0 bits (129), Expect = 6e-07
Identities = 52/205 (25%), Positives = 89/205 (43%), Gaps = 12/205 (5%)
Query: 92 IPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPG 151
IPV + + D+NDN P ++ Y V E +D D G + + Y++ G
Sbjct: 146 IPVYLEIVDINDNNPIFDQPSYQEAVFEDVPVGTIILTVTATDADS-GNFALIEYSLGDG 204
Query: 152 PHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQ----GSPPLYSDTTLQVTVLD 207
S++ N I V LD E +++ + +D S + + + VLD
Sbjct: 205 -ESKFA--INPTTGDIYVLSSLDREKKDHYILTALAKDNPGDVASNRRENSVQVVIQVLD 261
Query: 208 ADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIV 267
+D P+F+ ++ + ++ GT + T + A DQD G N L YS G +
Sbjct: 262 VNDCRPQFSKPQFSTSVYENEPAGTSVIT----MMATDQDEGPNGELTYSLEGPGVEAFH 317
Query: 268 VNKDTGQVAATKQLIAELDPSVTIV 292
V+ D+G V + L + S+T+V
Sbjct: 318 VDMDSGLVTTQRPLQSYEKFSLTVV 342
Score = 54.0 bits (124), Expect = 2e-06
Identities = 66/247 (26%), Positives = 110/247 (44%), Gaps = 29/247 (11%)
Query: 50 IVPGSKNLTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQW- 108
I P S + + LDRE + S + V D + + P+ V + D++DN P +
Sbjct: 426 IDPISGLIQTAQRLDRESQAVYSLILV--ASDLGQPVPYETMQPLQVALEDIDDNEPLFV 483
Query: 109 ---EGAPY--AVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENEL 163
+G+P + V E + GP++ ++Y + G +E F +
Sbjct: 484 RPPKGSPQYQLLTVPEHSPRGTLVGNVTGAVDADEGPNAIVYYFIAAG--NEEKNFHLQP 541
Query: 164 EPIIVVKKPLDFE--TVNNFTIKLRVQDQGSPP--------LYSDTTLQ---VTVLDADD 210
+ ++V + LD E + +F +K +PP L +D TLQ V + D +D
Sbjct: 542 DGCLLVLRDLDREREAIFSFIVKASSNRSWTPPRGPSPTLDLVADLTLQEVRVVLEDIND 601
Query: 211 QNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDH--KQLIVV 268
Q P+FT YTA + DA+ G+ L + A D D+G N+ + YS H + L
Sbjct: 602 QPPRFTKAEYTAGVATDAKVGSELI----QVLALDADIGNNSLVFYSILAIHYFRALAND 657
Query: 269 NKDTGQV 275
++D GQV
Sbjct: 658 SEDVGQV 664
>AF152526-1|AAD43786.1| 878|Homo sapiens protocadherin gamma C5
short form protein protein.
Length = 878
Score = 92.7 bits (220), Expect = 5e-18
Identities = 85/312 (27%), Positives = 137/312 (43%), Gaps = 25/312 (8%)
Query: 11 ISEDTPIGSIIGTLSV-------NGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRAL 63
I E+ PIG+++ L+ NG GD T G+ P S + +L +
Sbjct: 251 IPENAPIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRN--LFGLDPSSGAIHVLGPI 308
Query: 64 DREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXX 123
D EE ++ R + + VI V V DVNDNAP+ A A V E+
Sbjct: 309 DFEESRF-YEIHARARDQGQPAMEGHCVIQVDVG--DVNDNAPEVLLASLANPVLESTPV 365
Query: 124 XXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTI 183
DRD G + + + P + EN ++ +PLD E +++ I
Sbjct: 366 GTVVGLFNVRDRDS-GRNGEVSLDISPDLPFQIKPSENHYS--LLTSQPLDREATSHYII 422
Query: 184 KLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISA 243
+L D GSP L+ T+++ + D +D P+F + YTA + ++ G+ L T ++A
Sbjct: 423 ELLASDAGSPSLHKHLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGSLLCT----VAA 478
Query: 244 ADQDLGINAPLQYSSTGDHKQ------LIVVNKDTGQVAATKQLIAELDPSVTIVLKATQ 297
+D D G NA L YS G+ Q + VN + G++ A + EL + IV+
Sbjct: 479 SDPDTGDNARLTYSIVGNQVQGAPASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRD 538
Query: 298 VDNPDRYALATL 309
+P +A +L
Sbjct: 539 SGSPPLHANTSL 550
Score = 92.7 bits (220), Expect = 5e-18
Identities = 81/314 (25%), Positives = 144/314 (45%), Gaps = 25/314 (7%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRA--LDREEK 68
+ E TP+G+++G +V S G+++L + I P + +LL + LDRE
Sbjct: 359 VLESTPVGTVVGLFNVRDRDSGRNGEVSLDISPD-LPFQIKPSENHYSLLTSQPLDRE-- 415
Query: 69 IGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXX 128
S+ + + + + + + + DVNDNAP++ Y + E
Sbjct: 416 -ATSHYIIELLASDAGSPSLHKHLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGSLLC 474
Query: 129 XXXXSDRDQPGPHSALHYAVLPG-----PHSEYLGFENELEPIIVVKKPLDFETVNNFTI 183
SD D G ++ L Y+++ P S ++ + N + I ++ D+E + I
Sbjct: 475 TVAASDPDT-GDNARLTYSIVGNQVQGAPASSFV-YVNPEDGRIFAQRTFDYELLQMLQI 532
Query: 184 KLRVQDQGSPPLYSDTTLQVTVLDADDQ-----NPKFTYEHYT-ALLPDDAEEGTFLTTS 237
+ V+D GSPPL+++T+L V VLD +D +P+ +EH LP A G+ +T
Sbjct: 533 VVGVRDSGSPPLHANTSLHVFVLDENDNAPAVLHPRPDWEHSAPQRLPRSAPPGSLVT-- 590
Query: 238 PGPISAADQDLGINAPLQYS--STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKA 295
++A D D G NA L YS L +V+ TG+V + L+ + + +V+
Sbjct: 591 --KVTAVDADAGHNAWLSYSLLPQSTAPGLFLVSTHTGEVRTARALLEDDSDTQQVVVLV 648
Query: 296 TQVDNPDRYALATL 309
+P + AT+
Sbjct: 649 RDNGDPSLSSTATV 662
Score = 85.0 bits (201), Expect = 1e-15
Identities = 108/447 (24%), Positives = 174/447 (38%), Gaps = 29/447 (6%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
+SV V D+NDNAP ++ + V + E +D D+ G + L Y+ G H
Sbjct: 228 ISVIVLDINDNAPTFQSSVLRVGIPENAPIGTLLLRLNATDPDE-GTNGQLDYSF--GDH 284
Query: 154 -SEYLGFENELEP---IIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDAD 209
SE + L+P I V P+DFE + I R +DQG P + +QV V D +
Sbjct: 285 TSEAVRNLFGLDPSSGAIHVLGPIDFEESRFYEIHARARDQGQPAMEGHCVIQVDVGDVN 344
Query: 210 DQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVN 269
D P E A L + E T + T G + D+D G N + + D I +
Sbjct: 345 DNAP----EVLLASLANPVLESTPVGTVVGLFNVRDRDSGRNGEVSLDISPDLPFQIKPS 400
Query: 270 KDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFT 329
++ + ++ L E I L A+ +P + T+ +F
Sbjct: 401 ENHYSLLTSQPLDREATSHYIIELLASDAGSPSLHKHLTIRLNISDVNDNAP-----RFN 455
Query: 330 QKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDR---SFLDKFAINNA--GE 384
Q+ Y+ + E PGS+L T+ +T V ++ + F N G
Sbjct: 456 QQLYTAYILENRPPGSLLCTVAASDPDTGDNARLTYSIVGNQVQGAPASSFVYVNPEDGR 515
Query: 385 VILRRSLDYETTSNYFYQVMVTDSIS---NDTASINISVEDVNEWEPRFRHPQYEFEXXX 441
+ +R+ DYE V V DS S + S+++ V D N+ P HP+ ++E
Sbjct: 516 IFAQRTFDYELLQMLQIVVGVRDSGSPPLHANTSLHVFVLDENDNAPAVLHPRPDWEHSA 575
Query: 442 XXXXXXXXXXXXXXXXXVAHDGDAG---TLALSLAGQHAR--MFYINASGDLFLREEAIG 496
A D DAG L+ SL Q +F ++ A+
Sbjct: 576 PQRLPRSAPPGSLVTKVTAVDADAGHNAWLSYSLLPQSTAPGLFLVSTHTGEVRTARALL 635
Query: 497 NLNSSSLHLVATAIDSGIPPRQTSVPV 523
+S + +V D+G P ++ V
Sbjct: 636 EDDSDTQQVVVLVRDNGDPSLSSTATV 662
Score = 81.0 bits (191), Expect = 2e-14
Identities = 102/443 (23%), Positives = 177/443 (39%), Gaps = 32/443 (7%)
Query: 9 FFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRL--QEKGAAVGIVPGSKNLTLLRALDR 65
+ + E++ G+++G ++ + G DL L+L +E G + S L + + +DR
Sbjct: 33 YSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLGSEENGRYFSLSLMSGALAVNQKIDR 92
Query: 66 EEKIGPS-NVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXX 124
E G S + + V+ T P +I V V + D+NDN+P + +R+SE+
Sbjct: 93 ESLCGASTSCLLPVQVV---TEHPLELIRVEVEILDLNDNSPSFATPEREMRISESAASG 149
Query: 125 XXXXXXXXSDRDQPGPHSALHYAVLPGPHSEY---LGFENELEPIIVVKKPLDFETVNNF 181
D D G ++ Y + P H + + P +V+++ LD E
Sbjct: 150 ARFPLDSAQDPDV-GTNTVSFYTLSPNSHFSLNVKTLKDGKPFPELVLEQQLDREAQARH 208
Query: 182 TIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPI 241
+ L D G+P T + V VLD +D P F +P++A GT L +
Sbjct: 209 QLVLTAVDGGTPARSGTTLISVIVLDINDNAPTFQSSVLRVGIPENAPIGTLLLR----L 264
Query: 242 SAADQDLGINAPLQYSSTGDH-----KQLIVVNKDTGQVAATKQLIAELDPSVTIVLKAT 296
+A D D G N L Y S GDH + L ++ +G + + E I +A
Sbjct: 265 NATDPDEGTNGQLDY-SFGDHTSEAVRNLFGLDPSSGAIHVLGPIDFEESRFYEIHARAR 323
Query: 297 QVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQN 356
P + +T P ++ L V
Sbjct: 324 DQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVLEST------PVGTVVGLFNVRDR 377
Query: 357 TEFRESPLQFYVS-DRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSIS---ND 412
R + +S D F K + N+ ++ + LD E TS+Y +++ +D+ S +
Sbjct: 378 DSGRNGEVSLDISPDLPFQIKPSENHY-SLLTSQPLDREATSHYIIELLASDAGSPSLHK 436
Query: 413 TASINISVEDVNEWEPRFRHPQY 435
+I +++ DVN+ PRF Y
Sbjct: 437 HLTIRLNISDVNDNAPRFNQQLY 459
>AF152339-1|AAD43733.1| 944|Homo sapiens protocadherin gamma C5
protein.
Length = 944
Score = 92.7 bits (220), Expect = 5e-18
Identities = 85/312 (27%), Positives = 137/312 (43%), Gaps = 25/312 (8%)
Query: 11 ISEDTPIGSIIGTLSV-------NGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRAL 63
I E+ PIG+++ L+ NG GD T G+ P S + +L +
Sbjct: 251 IPENAPIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRN--LFGLDPSSGAIHVLGPI 308
Query: 64 DREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXX 123
D EE ++ R + + VI V V DVNDNAP+ A A V E+
Sbjct: 309 DFEESRF-YEIHARARDQGQPAMEGHCVIQVDVG--DVNDNAPEVLLASLANPVLESTPV 365
Query: 124 XXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTI 183
DRD G + + + P + EN ++ +PLD E +++ I
Sbjct: 366 GTVVGLFNVRDRDS-GRNGEVSLDISPDLPFQIKPSENHYS--LLTSQPLDREATSHYII 422
Query: 184 KLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISA 243
+L D GSP L+ T+++ + D +D P+F + YTA + ++ G+ L T ++A
Sbjct: 423 ELLASDAGSPSLHKHLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGSLLCT----VAA 478
Query: 244 ADQDLGINAPLQYSSTGDHKQ------LIVVNKDTGQVAATKQLIAELDPSVTIVLKATQ 297
+D D G NA L YS G+ Q + VN + G++ A + EL + IV+
Sbjct: 479 SDPDTGDNARLTYSIVGNQVQGAPASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRD 538
Query: 298 VDNPDRYALATL 309
+P +A +L
Sbjct: 539 SGSPPLHANTSL 550
Score = 92.7 bits (220), Expect = 5e-18
Identities = 81/314 (25%), Positives = 144/314 (45%), Gaps = 25/314 (7%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRA--LDREEK 68
+ E TP+G+++G +V S G+++L + I P + +LL + LDRE
Sbjct: 359 VLESTPVGTVVGLFNVRDRDSGRNGEVSLDISPD-LPFQIKPSENHYSLLTSQPLDRE-- 415
Query: 69 IGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXX 128
S+ + + + + + + + DVNDNAP++ Y + E
Sbjct: 416 -ATSHYIIELLASDAGSPSLHKHLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGSLLC 474
Query: 129 XXXXSDRDQPGPHSALHYAVLPG-----PHSEYLGFENELEPIIVVKKPLDFETVNNFTI 183
SD D G ++ L Y+++ P S ++ + N + I ++ D+E + I
Sbjct: 475 TVAASDPDT-GDNARLTYSIVGNQVQGAPASSFV-YVNPEDGRIFAQRTFDYELLQMLQI 532
Query: 184 KLRVQDQGSPPLYSDTTLQVTVLDADDQ-----NPKFTYEHYT-ALLPDDAEEGTFLTTS 237
+ V+D GSPPL+++T+L V VLD +D +P+ +EH LP A G+ +T
Sbjct: 533 VVGVRDSGSPPLHANTSLHVFVLDENDNAPAVLHPRPDWEHSAPQRLPRSAPPGSLVT-- 590
Query: 238 PGPISAADQDLGINAPLQYS--STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKA 295
++A D D G NA L YS L +V+ TG+V + L+ + + +V+
Sbjct: 591 --KVTAVDADAGHNAWLSYSLLPQSTAPGLFLVSTHTGEVRTARALLEDDSDTQQVVVLV 648
Query: 296 TQVDNPDRYALATL 309
+P + AT+
Sbjct: 649 RDNGDPSLSSTATV 662
Score = 85.0 bits (201), Expect = 1e-15
Identities = 108/447 (24%), Positives = 174/447 (38%), Gaps = 29/447 (6%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
+SV V D+NDNAP ++ + V + E +D D+ G + L Y+ G H
Sbjct: 228 ISVIVLDINDNAPTFQSSVLRVGIPENAPIGTLLLRLNATDPDE-GTNGQLDYSF--GDH 284
Query: 154 -SEYLGFENELEP---IIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDAD 209
SE + L+P I V P+DFE + I R +DQG P + +QV V D +
Sbjct: 285 TSEAVRNLFGLDPSSGAIHVLGPIDFEESRFYEIHARARDQGQPAMEGHCVIQVDVGDVN 344
Query: 210 DQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVN 269
D P E A L + E T + T G + D+D G N + + D I +
Sbjct: 345 DNAP----EVLLASLANPVLESTPVGTVVGLFNVRDRDSGRNGEVSLDISPDLPFQIKPS 400
Query: 270 KDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFT 329
++ + ++ L E I L A+ +P + T+ +F
Sbjct: 401 ENHYSLLTSQPLDREATSHYIIELLASDAGSPSLHKHLTIRLNISDVNDNAP-----RFN 455
Query: 330 QKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDR---SFLDKFAINNA--GE 384
Q+ Y+ + E PGS+L T+ +T V ++ + F N G
Sbjct: 456 QQLYTAYILENRPPGSLLCTVAASDPDTGDNARLTYSIVGNQVQGAPASSFVYVNPEDGR 515
Query: 385 VILRRSLDYETTSNYFYQVMVTDSIS---NDTASINISVEDVNEWEPRFRHPQYEFEXXX 441
+ +R+ DYE V V DS S + S+++ V D N+ P HP+ ++E
Sbjct: 516 IFAQRTFDYELLQMLQIVVGVRDSGSPPLHANTSLHVFVLDENDNAPAVLHPRPDWEHSA 575
Query: 442 XXXXXXXXXXXXXXXXXVAHDGDAG---TLALSLAGQHAR--MFYINASGDLFLREEAIG 496
A D DAG L+ SL Q +F ++ A+
Sbjct: 576 PQRLPRSAPPGSLVTKVTAVDADAGHNAWLSYSLLPQSTAPGLFLVSTHTGEVRTARALL 635
Query: 497 NLNSSSLHLVATAIDSGIPPRQTSVPV 523
+S + +V D+G P ++ V
Sbjct: 636 EDDSDTQQVVVLVRDNGDPSLSSTATV 662
Score = 81.0 bits (191), Expect = 2e-14
Identities = 102/443 (23%), Positives = 177/443 (39%), Gaps = 32/443 (7%)
Query: 9 FFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRL--QEKGAAVGIVPGSKNLTLLRALDR 65
+ + E++ G+++G ++ + G DL L+L +E G + S L + + +DR
Sbjct: 33 YSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLGSEENGRYFSLSLMSGALAVNQKIDR 92
Query: 66 EEKIGPS-NVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXX 124
E G S + + V+ T P +I V V + D+NDN+P + +R+SE+
Sbjct: 93 ESLCGASTSCLLPVQVV---TEHPLELIRVEVEILDLNDNSPSFATPEREMRISESAASG 149
Query: 125 XXXXXXXXSDRDQPGPHSALHYAVLPGPHSEY---LGFENELEPIIVVKKPLDFETVNNF 181
D D G ++ Y + P H + + P +V+++ LD E
Sbjct: 150 ARFPLDSAQDPDV-GTNTVSFYTLSPNSHFSLNVKTLKDGKPFPELVLEQQLDREAQARH 208
Query: 182 TIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPI 241
+ L D G+P T + V VLD +D P F +P++A GT L +
Sbjct: 209 QLVLTAVDGGTPARSGTTLISVIVLDINDNAPTFQSSVLRVGIPENAPIGTLLLR----L 264
Query: 242 SAADQDLGINAPLQYSSTGDH-----KQLIVVNKDTGQVAATKQLIAELDPSVTIVLKAT 296
+A D D G N L Y S GDH + L ++ +G + + E I +A
Sbjct: 265 NATDPDEGTNGQLDY-SFGDHTSEAVRNLFGLDPSSGAIHVLGPIDFEESRFYEIHARAR 323
Query: 297 QVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQN 356
P + +T P ++ L V
Sbjct: 324 DQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVLEST------PVGTVVGLFNVRDR 377
Query: 357 TEFRESPLQFYVS-DRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSIS---ND 412
R + +S D F K + N+ ++ + LD E TS+Y +++ +D+ S +
Sbjct: 378 DSGRNGEVSLDISPDLPFQIKPSENHY-SLLTSQPLDREATSHYIIELLASDAGSPSLHK 436
Query: 413 TASINISVEDVNEWEPRFRHPQY 435
+I +++ DVN+ PRF Y
Sbjct: 437 HLTIRLNISDVNDNAPRFNQQLY 459
>AB209225-1|BAD92462.1| 799|Homo sapiens protocadherin beta 11
precursor variant protein.
Length = 799
Score = 92.7 bits (220), Expect = 5e-18
Identities = 100/448 (22%), Positives = 190/448 (42%), Gaps = 33/448 (7%)
Query: 3 GGAVESFFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRL--QEKGAAVGIVPGSKNLTL 59
G SF ++E+ GS +G L+ + G +L R+ +K + + + +L L
Sbjct: 29 GSETWSFSVAEEMQSGSFVGNLAKDLGLKVRELSSRGARVVSNDKKQRLQLDINTGDLLL 88
Query: 60 LRALDREEKIG---PSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVR 116
LDREE G P +++ V +P+ + + ++V D+ND++P + +
Sbjct: 89 SETLDREELCGSIEPCVLHLQVLMQ-----NPTQFLQIELQVRDINDHSPIFSEKQMLLE 143
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEY---LGFENELEPIIVVKKPL 173
+ E D D G ++ Y + P H + +N P +V+ K L
Sbjct: 144 IPENSPVGAVFLLESAKDLDV-GINAVKSYTISPNSHFHIKMRVIPDNRKYPELVLDKAL 202
Query: 174 DFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTF 233
D+E + + L D GSPP ++V V+D +D +P+F Y + +++ G+
Sbjct: 203 DYEELPELSFILSALDGGSPPRSGTALVRVVVVDINDNSPEFEQAFYEVKIRENSILGSL 262
Query: 234 LTTSPGPISAADQDLGINAPLQYS---STGDHKQLIVVNKDTGQVAATKQLIAELDPSVT 290
+ +SA D D G N + Y+ ++ D ++ +N+ +G++ L E S +
Sbjct: 263 ILI----VSAWDLDSGTNGEICYTFSHASEDIRKTFEINQKSGEITLRAPLDFETIESYS 318
Query: 291 IVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTL 350
I+++AT D + +T+ + T ++ + E +P +V++
Sbjct: 319 IIIQAT--DGGGLFGKSTVIIHVIDVNDNAP-----EITVSSITSPIPEN-TPETVVMVF 370
Query: 351 TTVPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTD-SI 409
+ ++ + D F+ K ++ N + R LD E+T+ Y + VTD I
Sbjct: 371 SIQDIDSGDNGRIVCSIPEDLPFVLKSSVENYHTLETERPLDRESTAEYNITITVTDLGI 430
Query: 410 SNDTASIN--ISVEDVNEWEPRFRHPQY 435
N + V DVN+ P F Y
Sbjct: 431 PRLKTEHNTTVLVSDVNDNAPTFTQTSY 458
Score = 87.0 bits (206), Expect = 3e-16
Identities = 108/441 (24%), Positives = 168/441 (38%), Gaps = 27/441 (6%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
V V V D+NDN+P++E A Y V++ E D D G + + Y
Sbjct: 230 VRVVVVDINDNSPEFEQAFYEVKIRENSILGSLILIVSAWDLDS-GTNGEICYTFSHASE 288
Query: 154 SEYLGFE-NELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQN 212
FE N+ I ++ PLDFET+ +++I ++ D G L+ +T+ + V+D +D
Sbjct: 289 DIRKTFEINQKSGEITLRAPLDFETIESYSIIIQATDGGG--LFGKSTVIIHVIDVNDNA 346
Query: 213 PKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDT 272
P+ T T+ +P++ E + S D D G N + S D ++ + +
Sbjct: 347 PEITVSSITSPIPENTPETVVMV-----FSIQDIDSGDNGRIVCSIPEDLPFVLKSSVEN 401
Query: 273 GQVAATKQ-LIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQK 331
T++ L E I + T + P L T FTQ
Sbjct: 402 YHTLETERPLDRESTAEYNITITVTDLGIP---RLKTEHNTTVLVSDVNDNAPT--FTQT 456
Query: 332 QYSTTVSEGASP----GSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVI 386
Y+ V E SP GSV T N + S L +IN + G +
Sbjct: 457 SYTLFVRENNSPALHIGSVSATDRDSGTNAQVNYSLLPPQDLHLPLASLVSINTDNGHLF 516
Query: 387 LRRSLDYETTSNYFYQVMVTDSIS---NDTASINISVEDVNEWEPRFRHPQYEFEXXXXX 443
RSLDYE + ++V TD S + A + + V D N+ P +P
Sbjct: 517 ALRSLDYEALQAFDFRVGATDRGSPALSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTE 576
Query: 444 XXXXXXXXXXXXXXXVAHDGDAGTLA-LS---LAGQHARMFYINASGDLFLREEAIGNLN 499
VA DGD+G A LS L +F + A + +
Sbjct: 577 LVPRAAEPGYLVTKVVAVDGDSGQNAWLSYQLLKATEPGLFGVWAHNGEVRTARLLSERD 636
Query: 500 SSSLHLVATAIDSGIPPRQTS 520
++ LV D+G PPR +
Sbjct: 637 AAKHRLVVLVKDNGEPPRSAT 657
Score = 77.0 bits (181), Expect = 3e-13
Identities = 90/316 (28%), Positives = 136/316 (43%), Gaps = 30/316 (9%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAV--GIVPGSKNLTLLRALDREEK 68
I E+TP +++ S+ S D G I + E V V L R LDRE
Sbjct: 358 IPENTP-ETVVMVFSIQDIDSGDNGRIVCSIPEDLPFVLKSSVENYHTLETERPLDREST 416
Query: 69 IGPSNVYVNVRC--DRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXX 126
N+ + V R T+ + + VS DVNDNAP + Y + V E
Sbjct: 417 -AEYNITITVTDLGIPRLKTEHNTTVLVS----DVNDNAPTFTQTSYTLFVRENNSPALH 471
Query: 127 XXXXXXSDRDQPGPHSALHYAVLPG-----PHSEYLGFENELEPIIVVKKPLDFETVNNF 181
+DRD G ++ ++Y++LP P + + + + ++ LD+E + F
Sbjct: 472 IGSVSATDRDS-GTNAQVNYSLLPPQDLHLPLASLVSINTDNGHLFALRS-LDYEALQAF 529
Query: 182 TIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTY------EHYTALLPDDAEEGTFLT 235
++ D+GSP L S+ ++V VLDA+D +P Y T L+P AE G +T
Sbjct: 530 DFRVGATDRGSPALSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVT 589
Query: 236 TSPGPISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPSV-TIVL 293
+ A D D G NA L Y L V G+V T +L++E D + +V+
Sbjct: 590 ----KVVAVDGDSGQNAWLSYQLLKATEPGLFGVWAHNGEV-RTARLLSERDAAKHRLVV 644
Query: 294 KATQVDNPDRYALATL 309
P R A ATL
Sbjct: 645 LVKDNGEPPRSATATL 660
>AB053445-1|BAB61902.1| 1147|Homo sapiens KIAA1774 protein protein.
Length = 1147
Score = 92.7 bits (220), Expect = 5e-18
Identities = 101/454 (22%), Positives = 197/454 (43%), Gaps = 42/454 (9%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEK-- 68
+ ED P+G+II T++ S + I L + + I P + ++ +L +LDRE+K
Sbjct: 239 VFEDVPVGTIILTVTATDADSGNFALIEYSLGDGESKFAINPTTGDIYVLSSLDREKKDH 298
Query: 69 -----IGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXX 123
+ N +V +RR + + V ++V DVND PQ+ ++ V E
Sbjct: 299 YILTALAKDNP-GDVASNRRENS-----VQVVIQVLDVNDCRPQFSKPQFSTSVYENEPA 352
Query: 124 XXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTI 183
+D+D+ GP+ L Y+ L GP E + + ++ ++PL ++ F++
Sbjct: 353 GTSVITMMATDQDE-GPNGELTYS-LEGPGVEAFHVDMD-SGLVTTQRPL--QSYEKFSL 407
Query: 184 KLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISA 243
+ D G PPL+ T L V V+D +D P F +L E L ++ + A
Sbjct: 408 TVVATDGGEPPLWGTTMLLVEVIDVNDNRPVFVRPPNGTIL--HIREEIPLRSNVYEVYA 465
Query: 244 ADQDLGINAPLQYS--STGDHK--QLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVD 299
D+D G+N ++YS T ++ + +++ +G + ++L E +++L A+ +
Sbjct: 466 TDKDEGLNGAVRYSFLKTAGNRDWEFFIIDPISGLIQTAQRLDRESQAVYSLILVASDLG 525
Query: 300 NPDRY-ALATLXXXXXXXXXXXXXXXXLQFTQKQYS-TTVSEGASPGSVLLTLTTVPQNT 357
P Y + L QY TV E + G+++ +T
Sbjct: 526 QPVPYETMQPLQVALEDIDDNEPLFVRPPKGSPQYQLLTVPEHSPRGTLVGNVTGAVDAD 585
Query: 358 EFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVT----------- 406
E + + ++++ + F + G +++ R LD E + + + V +
Sbjct: 586 EGPNAIVYYFIAAGNEEKNFHLQPDGCLLVLRDLDREREAIFSFIVKASSNRSWTPPRGP 645
Query: 407 ----DSISNDT-ASINISVEDVNEWEPRFRHPQY 435
D +++ T + + +ED+N+ PRF +Y
Sbjct: 646 SPTLDLVADLTLQEVRVVLEDINDQPPRFTKAEY 679
Score = 91.5 bits (217), Expect = 1e-17
Identities = 87/348 (25%), Positives = 151/348 (43%), Gaps = 20/348 (5%)
Query: 94 VSVRVWDVNDNAPQWE--GAPYAV-RVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLP 150
++V V DVNDN PQ++ G Y + R+ E D D+ G + + Y +L
Sbjct: 107 LTVNVLDVNDNTPQFKPFGITYYMERILEGATPGTTLIAVAAVDPDK-GLNGLVTYTLLD 165
Query: 151 GPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADD 210
Y+ E+ ++ + +D+E V+ +R D GSPP ++ + + ++D +D
Sbjct: 166 LVPPGYVQLEDSSAGKVIANRTVDYEEVHWLNFTVRASDNGSPPRAAEIPVYLEIVDIND 225
Query: 211 QNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNK 270
NP F Y + +D GT + T ++A D D G A ++Y S GD + +N
Sbjct: 226 NNPIFDQPSYQEAVFEDVPVGTIILT----VTATDADSGNFALIEY-SLGDGESKFAINP 280
Query: 271 DTGQVAATKQLIAELDPSVTIVLKATQVDNP-DRYALATLXXXXXXXXXXXXXXXXLQFT 329
TG + L + + +L A DNP D + QF+
Sbjct: 281 TTGDIYVLSSL--DREKKDHYILTALAKDNPGDVASNRRENSVQVVIQVLDVNDCRPQFS 338
Query: 330 QKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILR 388
+ Q+ST+V E G+ ++T+ Q+ E L Y + ++ F ++ ++G V +
Sbjct: 339 KPQFSTSVYENEPAGTSVITMMATDQD-EGPNGELT-YSLEGPGVEAFHVDMDSGLVTTQ 396
Query: 389 RSLDYETTSNYFYQVMVTDSISN---DTASINISVEDVNEWEPRFRHP 433
R L ++ + V+ TD T + + V DVN+ P F P
Sbjct: 397 RPL--QSYEKFSLTVVATDGGEPPLWGTTMLLVEVIDVNDNRPVFVRP 442
Score = 75.8 bits (178), Expect = 6e-13
Identities = 90/368 (24%), Positives = 149/368 (40%), Gaps = 35/368 (9%)
Query: 167 IVVKKPLDFETVNNFTIKLRVQDQGSP-PLYS----DTTLQVTVLDADDQNPKFT---YE 218
++VK P++ E V + + L V D S P S + L V VLD +D P+F
Sbjct: 68 VMVKSPMNRELVATYEVTLSVIDNASDLPERSVSVPNAKLTVNVLDVNDNTPQFKPFGIT 127
Query: 219 HYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDT--GQVA 276
+Y + + A GT L ++A D D G+N + Y+ V +D+ G+V
Sbjct: 128 YYMERILEGATPGTTLIA----VAAVDPDKGLNGLVTYTLLDLVPPGYVQLEDSSAGKVI 183
Query: 277 ATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTT 336
A + + E + ++A+ +P R A + F Q Y
Sbjct: 184 ANRTVDYEEVHWLNFTVRASDNGSPPRAAEIPVYLEIVDINDNNPI-----FDQPSYQEA 238
Query: 337 VSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYET 395
V E G+++LT+T ++ + +++ + D KFAIN G++ + SLD E
Sbjct: 239 VFEDVPVGTIILTVTATDADSG-NFALIEYSLGDGE--SKFAINPTTGDIYVLSSLDREK 295
Query: 396 TSNYFYQVMVTDS----ISN---DTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXX 448
+Y + D+ SN ++ + I V DVN+ P+F PQ+
Sbjct: 296 KDHYILTALAKDNPGDVASNRRENSVQVVIQVLDVNDCRPQFSKPQFSTSVYENEPAGTS 355
Query: 449 XXXXXXXXXXVAHDGDAGTLALSLAGQHARMFYINASGDLFLREEAIGNLNSSSLHLVAT 508
+G G L SL G F+++ L + + + SL +VAT
Sbjct: 356 VITMMATDQD---EGPNGELTYSLEGPGVEAFHVDMDSGLVTTQRPLQSYEKFSLTVVAT 412
Query: 509 AIDSGIPP 516
D G PP
Sbjct: 413 --DGGEPP 418
Score = 56.0 bits (129), Expect = 6e-07
Identities = 52/205 (25%), Positives = 89/205 (43%), Gaps = 12/205 (5%)
Query: 92 IPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPG 151
IPV + + D+NDN P ++ Y V E +D D G + + Y++ G
Sbjct: 214 IPVYLEIVDINDNNPIFDQPSYQEAVFEDVPVGTIILTVTATDADS-GNFALIEYSLGDG 272
Query: 152 PHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQ----GSPPLYSDTTLQVTVLD 207
S++ N I V LD E +++ + +D S + + + VLD
Sbjct: 273 -ESKFA--INPTTGDIYVLSSLDREKKDHYILTALAKDNPGDVASNRRENSVQVVIQVLD 329
Query: 208 ADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIV 267
+D P+F+ ++ + ++ GT + T + A DQD G N L YS G +
Sbjct: 330 VNDCRPQFSKPQFSTSVYENEPAGTSVIT----MMATDQDEGPNGELTYSLEGPGVEAFH 385
Query: 268 VNKDTGQVAATKQLIAELDPSVTIV 292
V+ D+G V + L + S+T+V
Sbjct: 386 VDMDSGLVTTQRPLQSYEKFSLTVV 410
Score = 54.0 bits (124), Expect = 2e-06
Identities = 66/247 (26%), Positives = 110/247 (44%), Gaps = 29/247 (11%)
Query: 50 IVPGSKNLTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQW- 108
I P S + + LDRE + S + V D + + P+ V + D++DN P +
Sbjct: 494 IDPISGLIQTAQRLDRESQAVYSLILV--ASDLGQPVPYETMQPLQVALEDIDDNEPLFV 551
Query: 109 ---EGAPY--AVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENEL 163
+G+P + V E + GP++ ++Y + G +E F +
Sbjct: 552 RPPKGSPQYQLLTVPEHSPRGTLVGNVTGAVDADEGPNAIVYYFIAAG--NEEKNFHLQP 609
Query: 164 EPIIVVKKPLDFE--TVNNFTIKLRVQDQGSPP--------LYSDTTLQ---VTVLDADD 210
+ ++V + LD E + +F +K +PP L +D TLQ V + D +D
Sbjct: 610 DGCLLVLRDLDREREAIFSFIVKASSNRSWTPPRGPSPTLDLVADLTLQEVRVVLEDIND 669
Query: 211 QNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDH--KQLIVV 268
Q P+FT YTA + DA+ G+ L + A D D+G N+ + YS H + L
Sbjct: 670 QPPRFTKAEYTAGVATDAKVGSELI----QVLALDADIGNNSLVFYSILAIHYFRALAND 725
Query: 269 NKDTGQV 275
++D GQV
Sbjct: 726 SEDVGQV 732
>BC113611-1|AAI13612.1| 797|Homo sapiens protocadherin beta 11
protein.
Length = 797
Score = 92.3 bits (219), Expect = 7e-18
Identities = 100/448 (22%), Positives = 190/448 (42%), Gaps = 33/448 (7%)
Query: 3 GGAVESFFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRL--QEKGAAVGIVPGSKNLTL 59
G SF ++E+ GS +G L+ + G +L R+ +K + + + +L L
Sbjct: 27 GSETWSFSVAEEMQSGSFVGNLAKDLGLKVRELSSRGARVVSNDKKQRLQLDINTGDLLL 86
Query: 60 LRALDREEKIG---PSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVR 116
LDREE G P +++ V +P+ + + ++V D+ND++P + +
Sbjct: 87 SETLDREELCGSIEPCVLHLQVLMQ-----NPTQFLQIELQVRDINDHSPIFSEKQMLLE 141
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEY---LGFENELEPIIVVKKPL 173
+ E D D G ++ Y + P H + +N P +V+ K L
Sbjct: 142 IPENSPVGAVFLLESAKDLDV-GINAVKSYTISPNSHFHIKMRVIPDNRKYPELVLDKAL 200
Query: 174 DFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTF 233
D+E + + L D GSPP ++V V+D +D +P+F Y + +++ G+
Sbjct: 201 DYEELPELSFILSALDGGSPPRSGTALVRVVVVDINDNSPEFEQAFYEVKIRENSILGSL 260
Query: 234 LTTSPGPISAADQDLGINAPLQYS---STGDHKQLIVVNKDTGQVAATKQLIAELDPSVT 290
+ +SA D D G N + Y+ ++ D ++ +N+ +G++ L E S +
Sbjct: 261 ILI----VSAWDLDSGTNGEICYTFSHASEDIRKTFEINQKSGEITLRAPLDFETIESYS 316
Query: 291 IVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTL 350
I+++AT D + +T+ + T ++ + E +P +V++
Sbjct: 317 IIIQAT--DGGGLFGKSTVIIHVIDVNDNAP-----EITVSSITSPIPEN-TPETVVMVF 368
Query: 351 TTVPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTD-SI 409
+ ++ + D F+ K ++ N + R LD E+T+ Y + VTD I
Sbjct: 369 SIQDIDSGDNGRIVCSIPEDLPFVLKSSVENYYTLETERPLDRESTAEYNITITVTDLGI 428
Query: 410 SNDTASIN--ISVEDVNEWEPRFRHPQY 435
N + V DVN+ P F Y
Sbjct: 429 PRLKTEHNTTVLVSDVNDNAPTFTQTSY 456
Score = 86.6 bits (205), Expect = 3e-16
Identities = 108/441 (24%), Positives = 168/441 (38%), Gaps = 27/441 (6%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
V V V D+NDN+P++E A Y V++ E D D G + + Y
Sbjct: 228 VRVVVVDINDNSPEFEQAFYEVKIRENSILGSLILIVSAWDLDS-GTNGEICYTFSHASE 286
Query: 154 SEYLGFE-NELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQN 212
FE N+ I ++ PLDFET+ +++I ++ D G L+ +T+ + V+D +D
Sbjct: 287 DIRKTFEINQKSGEITLRAPLDFETIESYSIIIQATDGGG--LFGKSTVIIHVIDVNDNA 344
Query: 213 PKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDT 272
P+ T T+ +P++ E + S D D G N + S D ++ + +
Sbjct: 345 PEITVSSITSPIPENTPETVVMV-----FSIQDIDSGDNGRIVCSIPEDLPFVLKSSVEN 399
Query: 273 GQVAATKQ-LIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQK 331
T++ L E I + T + P L T FTQ
Sbjct: 400 YYTLETERPLDRESTAEYNITITVTDLGIP---RLKTEHNTTVLVSDVNDNAPT--FTQT 454
Query: 332 QYSTTVSEGASP----GSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVI 386
Y+ V E SP GSV T N + S L +IN + G +
Sbjct: 455 SYTLFVRENNSPALHIGSVSATDRDSGTNAQVNYSLLPPQDLHLPLASLVSINTDNGHLF 514
Query: 387 LRRSLDYETTSNYFYQVMVTDSIS---NDTASINISVEDVNEWEPRFRHPQYEFEXXXXX 443
RSLDYE + ++V TD S + A + + V D N+ P +P
Sbjct: 515 ALRSLDYEALQAFDFRVGATDRGSPALSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTE 574
Query: 444 XXXXXXXXXXXXXXXVAHDGDAGTLA-LS---LAGQHARMFYINASGDLFLREEAIGNLN 499
VA DGD+G A LS L +F + A + +
Sbjct: 575 LVPRAAEPGYLVTKVVAVDGDSGQNAWLSYQLLKATEPGLFGVWAHNGEVRTARLLSERD 634
Query: 500 SSSLHLVATAIDSGIPPRQTS 520
++ LV D+G PPR +
Sbjct: 635 AAKHRLVVLVKDNGEPPRSAT 655
Score = 76.6 bits (180), Expect = 4e-13
Identities = 90/316 (28%), Positives = 136/316 (43%), Gaps = 30/316 (9%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAV--GIVPGSKNLTLLRALDREEK 68
I E+TP +++ S+ S D G I + E V V L R LDRE
Sbjct: 356 IPENTP-ETVVMVFSIQDIDSGDNGRIVCSIPEDLPFVLKSSVENYYTLETERPLDREST 414
Query: 69 IGPSNVYVNVRC--DRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXX 126
N+ + V R T+ + + VS DVNDNAP + Y + V E
Sbjct: 415 -AEYNITITVTDLGIPRLKTEHNTTVLVS----DVNDNAPTFTQTSYTLFVRENNSPALH 469
Query: 127 XXXXXXSDRDQPGPHSALHYAVLPG-----PHSEYLGFENELEPIIVVKKPLDFETVNNF 181
+DRD G ++ ++Y++LP P + + + + ++ LD+E + F
Sbjct: 470 IGSVSATDRDS-GTNAQVNYSLLPPQDLHLPLASLVSINTDNGHLFALRS-LDYEALQAF 527
Query: 182 TIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTY------EHYTALLPDDAEEGTFLT 235
++ D+GSP L S+ ++V VLDA+D +P Y T L+P AE G +T
Sbjct: 528 DFRVGATDRGSPALSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVT 587
Query: 236 TSPGPISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPSV-TIVL 293
+ A D D G NA L Y L V G+V T +L++E D + +V+
Sbjct: 588 ----KVVAVDGDSGQNAWLSYQLLKATEPGLFGVWAHNGEV-RTARLLSERDAAKHRLVV 642
Query: 294 KATQVDNPDRYALATL 309
P R A ATL
Sbjct: 643 LVKDNGEPPRSATATL 658
>BC112132-1|AAI12133.1| 797|Homo sapiens protocadherin beta 11
protein.
Length = 797
Score = 92.3 bits (219), Expect = 7e-18
Identities = 100/448 (22%), Positives = 190/448 (42%), Gaps = 33/448 (7%)
Query: 3 GGAVESFFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRL--QEKGAAVGIVPGSKNLTL 59
G SF ++E+ GS +G L+ + G +L R+ +K + + + +L L
Sbjct: 27 GSETWSFSVAEEMQSGSFVGNLAKDLGLKVRELSSRGARVVSNDKKQRLQLDINTGDLLL 86
Query: 60 LRALDREEKIG---PSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVR 116
LDREE G P +++ V +P+ + + ++V D+ND++P + +
Sbjct: 87 SETLDREELCGSIEPCVLHLQVLMQ-----NPTQFLQIELQVRDINDHSPIFSEKQMLLE 141
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEY---LGFENELEPIIVVKKPL 173
+ E D D G ++ Y + P H + +N P +V+ K L
Sbjct: 142 IPENSPVGAVFLLESAKDLDV-GINAVKSYTISPNSHFHIKMRVIPDNRKYPELVLDKAL 200
Query: 174 DFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTF 233
D+E + + L D GSPP ++V V+D +D +P+F Y + +++ G+
Sbjct: 201 DYEELPELSFILSALDGGSPPRSGTALVRVVVVDINDNSPEFEQAFYEVKIRENSILGSL 260
Query: 234 LTTSPGPISAADQDLGINAPLQYS---STGDHKQLIVVNKDTGQVAATKQLIAELDPSVT 290
+ +SA D D G N + Y+ ++ D ++ +N+ +G++ L E S +
Sbjct: 261 ILI----VSAWDLDSGTNGEICYTFSHASEDIRKTFEINQKSGEITLRAPLDFETIESYS 316
Query: 291 IVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTL 350
I+++AT D + +T+ + T ++ + E +P +V++
Sbjct: 317 IIIQAT--DGGGLFGKSTVIIHVIDVNDNAP-----EITVSSITSPIPEN-TPETVVMVF 368
Query: 351 TTVPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTD-SI 409
+ ++ + D F+ K ++ N + R LD E+T+ Y + VTD I
Sbjct: 369 SIQDIDSGDNGRIVCSIPEDLPFVLKSSVENYYTLETERPLDRESTAEYNITITVTDLGI 428
Query: 410 SNDTASIN--ISVEDVNEWEPRFRHPQY 435
N + V DVN+ P F Y
Sbjct: 429 PRLKTEHNTTVLVSDVNDNAPTFTQTSY 456
Score = 86.6 bits (205), Expect = 3e-16
Identities = 108/441 (24%), Positives = 168/441 (38%), Gaps = 27/441 (6%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
V V V D+NDN+P++E A Y V++ E D D G + + Y
Sbjct: 228 VRVVVVDINDNSPEFEQAFYEVKIRENSILGSLILIVSAWDLDS-GTNGEICYTFSHASE 286
Query: 154 SEYLGFE-NELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQN 212
FE N+ I ++ PLDFET+ +++I ++ D G L+ +T+ + V+D +D
Sbjct: 287 DIRKTFEINQKSGEITLRAPLDFETIESYSIIIQATDGGG--LFGKSTVIIHVIDVNDNA 344
Query: 213 PKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDT 272
P+ T T+ +P++ E + S D D G N + S D ++ + +
Sbjct: 345 PEITVSSITSPIPENTPETVVMV-----FSIQDIDSGDNGRIVCSIPEDLPFVLKSSVEN 399
Query: 273 GQVAATKQ-LIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQK 331
T++ L E I + T + P L T FTQ
Sbjct: 400 YYTLETERPLDRESTAEYNITITVTDLGIP---RLKTEHNTTVLVSDVNDNAPT--FTQT 454
Query: 332 QYSTTVSEGASP----GSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVI 386
Y+ V E SP GSV T N + S L +IN + G +
Sbjct: 455 SYTLFVRENNSPALHIGSVSATDRDSGTNAQVNYSLLPPQDLHLPLASLVSINTDNGHLF 514
Query: 387 LRRSLDYETTSNYFYQVMVTDSIS---NDTASINISVEDVNEWEPRFRHPQYEFEXXXXX 443
RSLDYE + ++V TD S + A + + V D N+ P +P
Sbjct: 515 ALRSLDYEALQAFDFRVGATDRGSPALSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTE 574
Query: 444 XXXXXXXXXXXXXXXVAHDGDAGTLA-LS---LAGQHARMFYINASGDLFLREEAIGNLN 499
VA DGD+G A LS L +F + A + +
Sbjct: 575 LVPRAAEPGYLVTKVVAVDGDSGQNAWLSYQLLKATEPGLFGVWAHNGEVRTARLLSERD 634
Query: 500 SSSLHLVATAIDSGIPPRQTS 520
++ LV D+G PPR +
Sbjct: 635 AAKHRLVVLVKDNGEPPRSAT 655
Score = 76.6 bits (180), Expect = 4e-13
Identities = 90/316 (28%), Positives = 136/316 (43%), Gaps = 30/316 (9%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAV--GIVPGSKNLTLLRALDREEK 68
I E+TP +++ S+ S D G I + E V V L R LDRE
Sbjct: 356 IPENTP-ETVVMVFSIQDIDSGDNGRIVCSIPEDLPFVLKSSVENYYTLETERPLDREST 414
Query: 69 IGPSNVYVNVRC--DRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXX 126
N+ + V R T+ + + VS DVNDNAP + Y + V E
Sbjct: 415 -AEYNITITVTDLGIPRLKTEHNTTVLVS----DVNDNAPTFTQTSYTLFVRENNSPALH 469
Query: 127 XXXXXXSDRDQPGPHSALHYAVLPG-----PHSEYLGFENELEPIIVVKKPLDFETVNNF 181
+DRD G ++ ++Y++LP P + + + + ++ LD+E + F
Sbjct: 470 IGSVSATDRDS-GTNAQVNYSLLPPQDLHLPLASLVSINTDNGHLFALRS-LDYEALQAF 527
Query: 182 TIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTY------EHYTALLPDDAEEGTFLT 235
++ D+GSP L S+ ++V VLDA+D +P Y T L+P AE G +T
Sbjct: 528 DFRVGATDRGSPALSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVT 587
Query: 236 TSPGPISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPSV-TIVL 293
+ A D D G NA L Y L V G+V T +L++E D + +V+
Sbjct: 588 ----KVVAVDGDSGQNAWLSYQLLKATEPGLFGVWAHNGEV-RTARLLSERDAAKHRLVV 642
Query: 294 KATQVDNPDRYALATL 309
P R A ATL
Sbjct: 643 LVKDNGEPPRSATATL 658
>BC065284-1|AAH65284.1| 1381|Homo sapiens CDH23 protein protein.
Length = 1381
Score = 92.3 bits (219), Expect = 7e-18
Identities = 102/440 (23%), Positives = 179/440 (40%), Gaps = 31/440 (7%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEKIG 70
ISEDTP+GS + L D D + +E + P + + L + LDRE K
Sbjct: 42 ISEDTPVGSSVTQLLAQ-DMDNDPLVFGVSGEEASRFFAVEPDTGVVWLRQPLDRETK-- 98
Query: 71 PSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXX 130
S V + V+++V DVNDNAP + PY+VR+ E
Sbjct: 99 -SEFTVEFSVSDHQGV---ITRKVNIQVGDVNDNAPTFHNQPYSVRIPENTPVGTPIFIV 154
Query: 131 XXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQ 190
+D D S L+ P S++ ++ I+ V + LD+ET + + + DQ
Sbjct: 155 NATDPDLGAGGSVLYSF---QPPSQFFAIDS-ARGIVTVIRELDYETTQAYQLTVNATDQ 210
Query: 191 G-SPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLG 249
+ PL + L + + D D +P F Y+ + + + GT + I+A DQD G
Sbjct: 211 DKTRPLSTLANLAIIITDVQDMDPIFINLPYSTNIYEHSPPGTTVRI----ITAIDQDKG 266
Query: 250 INAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAE---LDPSVTIVLKATQVDNPDRYA 305
+ Y+ +G+ + ++ +G + L E + +K T++ N DR
Sbjct: 267 RPRGIGYTIVSGNTNSIFALDYISGVLTLNGLLDRENPLYSHGFILTVKGTEL-NDDRTP 325
Query: 306 LATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVL-LTLTTVPQNTEF-RESP 363
+F +YS ++E A G L L + V ++ S
Sbjct: 326 SDATVTTTFNILVIDINDNAPEFNSSEYSVAITELAQVGFALPLFIQVVDKDENLGLNSM 385
Query: 364 LQFYV----SDRSFLDKFAINNAGEVILRRS--LDYETTSNYFYQVMVTDSISNDT--AS 415
+ Y+ S + ++ ++ +R + LDYET Y + + +S+ + A
Sbjct: 386 FEVYLVGNNSHHFIISPTSVQGKADIRIRVAIPLDYETVDRYDFDLFANESVPDHVGYAK 445
Query: 416 INISVEDVNEWEPRFRHPQY 435
+ I++ + N+ P F P Y
Sbjct: 446 VKITLINENDNRPIFSQPLY 465
Score = 84.2 bits (199), Expect = 2e-15
Identities = 105/449 (23%), Positives = 173/449 (38%), Gaps = 31/449 (6%)
Query: 91 VIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLP 150
+ V++ + D+NDN P W+ APY + + E D D G + L Y++ P
Sbjct: 761 IATVNITLLDINDNHPTWKDAPYYINLVEMTPPDSDVTTVVAVDPDL-GENGTLVYSIQP 819
Query: 151 GPHSEY-----LGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPL--YSDTTLQV 203
P+ Y G ++ + P E I + V D G PPL S T+ V
Sbjct: 820 -PNKFYSLNSTTGKIRTTHAMLDRENPDPHEAELMRKIVVSVTDCGRPPLKATSSATVFV 878
Query: 204 TVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQY-SSTGDH 262
+LD +D +P F + A + EG S + A D D G+N + Y G
Sbjct: 879 NLLDLNDNDPTFQNLPFVA----EVLEGIPAGVSIYQVVAIDLDEGLNGLVSYRMPVGMP 934
Query: 263 KQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXX 322
+ ++N +G V T +L E + + A+ P + + +TL
Sbjct: 935 RMDFLINSSSGVVVTTTELDRERIAKYQLRVVASDAGTPTKSSTSTLTIHVLDVNDETPT 994
Query: 323 XXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAINNA 382
F Y+ +VSE P + N + L ++++ + KF++
Sbjct: 995 -----FFPAVYNVSVSEDV-PREFRVVWLNCTDNDVGLNAELSYFITGGNVDGKFSVGYR 1048
Query: 383 GEVILR-RSLDYETTSNYFYQVMVTDS-----ISNDTASINISVEDVNEWEPRFRHPQYE 436
V+ LD ETT+ Y + D+ TA++ ++V DVN+ P F YE
Sbjct: 1049 DAVVRTVVGLDRETTAAYMLILEAIDNGPVGKRHTGTATVFVTVLDVNDNRPIFLQSSYE 1108
Query: 437 FEXXXXXXXXXXXXXXXXXXXXVAHDGDAGTLALS-LAGQHARMFYINASGDLFLR-EEA 494
A +G+ G + L G H F I+ S L +R
Sbjct: 1109 ---ASVPEDIPEGHSILQLKATDADEGEFGRVWYRILHGNHGNNFRIHVSNGLLMRGPRP 1165
Query: 495 IGNLNSSSLHLVATAIDSGIPPRQTSVPV 523
+ +SS L+ A + + P ++SV V
Sbjct: 1166 LDRERNSSHVLIVEAYNHDLGPMRSSVRV 1194
Score = 82.6 bits (195), Expect = 6e-15
Identities = 104/480 (21%), Positives = 181/480 (37%), Gaps = 33/480 (6%)
Query: 57 LTLLRALDREEKIGPSNVYVNVRC----DRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAP 112
LTL LDRE + + V+ D R +D + ++ V D+NDNAP++ +
Sbjct: 293 LTLNGLLDRENPLYSHGFILTVKGTELNDDRTPSDATVTTTFNILVIDINDNAPEFNSSE 352
Query: 113 YAVRVSETXXXXXXX-XXXXXSDRDQPGPHSALHYAVLPGPHSEYL-----GFENELEPI 166
Y+V ++E D+D+ +++ L G +S + + + +
Sbjct: 353 YSVAITELAQVGFALPLFIQVVDKDENLGLNSMFEVYLVGNNSHHFIISPTSVQGKADIR 412
Query: 167 IVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPD 226
I V PLD+ETV+ + L ++ P +++T+++ +D P F+ Y L +
Sbjct: 413 IRVAIPLDYETVDRYDFDL-FANESVPDHVGYAKVKITLINENDNRPIFSQPLYNISLYE 471
Query: 227 DAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLIAELD 286
+ GT + T + A D D G + Y + D + + +KDTG + +L EL
Sbjct: 472 NVTVGTSVLT----VLATDNDAGTFGEVSYFFSDDPDRFSL-DKDTGLIMLIARLDYELI 526
Query: 287 PSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSV 346
T+ + A + + F + Y + E +
Sbjct: 527 QRFTLTIIARDGGGEETTGRVRINVLDVNDNVPT-------FQKDAYVGALRENEPSVTQ 579
Query: 347 LLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAIN---NAGEVILRRSLDYETTSN--YFY 401
L+ L +++ VS +F F I+ G + + R LDYE SN +
Sbjct: 580 LVRLRATDEDSPPNNQITYSIVSASAFGSYFDISLYEGYGVISVSRPLDYEQISNGLIYL 639
Query: 402 QVMVTDSIS---NDTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXX 458
VM D+ + N T + I V D N+ P F P Y
Sbjct: 640 TVMAMDAGNPPLNSTVPVTIEVFDENDNPPTFSKPAYFVSVVENIMAGATVLFLNATDLD 699
Query: 459 VAHDGDAGTLALSLAGQHARMFYINASGDLFLREEAIGNLNSSSLHLVATAIDSGIPPRQ 518
+ + ++ SL G + F INA + S L+ A+D G+ Q
Sbjct: 700 RSREYGQESIIYSLEG--STQFRINARSGEITTTSLLDRETKSEYILIVRAVDGGVGHNQ 757
Score = 77.0 bits (181), Expect = 3e-13
Identities = 81/352 (23%), Positives = 144/352 (40%), Gaps = 24/352 (6%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPG-P 152
V V + D+NDN P ++ P+ V E D D+ G + + Y + G P
Sbjct: 876 VFVNLLDLNDNDPTFQNLPFVAEVLEGIPAGVSIYQVVAIDLDE-GLNGLVSYRMPVGMP 934
Query: 153 HSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQN 212
++L N ++V LD E + + +++ D G+P S +TL + VLD +D+
Sbjct: 935 RMDFL--INSSSGVVVTTTELDRERIAKYQLRVVASDAGTPTKSSTSTLTIHVLDVNDET 992
Query: 213 PKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQ-LIVVNKD 271
P F Y + +D + ++ D D+G+NA L Y TG + V
Sbjct: 993 PTFFPAVYNVSVSEDVPREFRVVW----LNCTDNDVGLNAELSYFITGGNVDGKFSVGYR 1048
Query: 272 TGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQK 331
V L E + ++L+A +DN T + F Q
Sbjct: 1049 DAVVRTVVGLDRETTAAYMLILEA--IDNGPVGKRHTGTATVFVTVLDVNDNRPI-FLQS 1105
Query: 332 QYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILR--R 389
Y +V E G +L L + E + + + + + F I+ + +++R R
Sbjct: 1106 SYEASVPEDIPEGHSILQLKATDAD-EGEFGRVWYRILHGNHGNNFRIHVSNGLLMRGPR 1164
Query: 390 SLDYETTSNYFYQVMVTDSISND------TASINISVEDVNEWEPRFRHPQY 435
LD E S++ V++ ++ ++D + + + VED+N+ P F QY
Sbjct: 1165 PLDRERNSSH---VLIVEAYNHDLGPMRSSVRVIVYVEDINDEAPVFTQQQY 1213
Score = 66.5 bits (155), Expect = 4e-10
Identities = 83/392 (21%), Positives = 146/392 (37%), Gaps = 17/392 (4%)
Query: 48 VGIVPGSKNLTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQ 107
+ + G +++ R LD E+ I +Y+ V + +PV++ V+D NDN P
Sbjct: 612 ISLYEGYGVISVSRPLDYEQ-ISNGLIYLTVMAMDAGNPPLNSTVPVTIEVFDENDNPPT 670
Query: 108 WEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPII 167
+ Y V V E +D D+ + +++ N I
Sbjct: 671 FSKPAYFVSVVENIMAGATVLFLNATDLDRSREYG--QESIIYSLEGSTQFRINARSGEI 728
Query: 168 VVKKPLDFETVNNFTIKLRVQD--QGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLP 225
LD ET + + + +R D G T+ +T+LD +D +P + Y L
Sbjct: 729 TTTSLLDRETKSEYILIVRAVDGGVGHNQKTGIATVNITLLDINDNHPTWKDAPYYINLV 788
Query: 226 DDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLI--A 283
+ + +TT + A D DLG N L YS +K +N TG++ T ++
Sbjct: 789 EMTPPDSDVTT----VVAVDPDLGENGTLVYSIQPPNK-FYSLNSTTGKIRTTHAMLDRE 843
Query: 284 ELDPSVTIVLKATQVDNPD--RYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGA 341
DP +++ V D R L F + V EG
Sbjct: 844 NPDPHEAELMRKIVVSVTDCGRPPLKATSSATVFVNLLDLNDNDPTFQNLPFVAEVLEGI 903
Query: 342 SPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFY 401
G + + + + +D +++G V+ LD E + Y
Sbjct: 904 PAGVSIYQVVAIDLDEGLNGLVSYRMPVGMPRMDFLINSSSGVVVTTTELDRERIAKYQL 963
Query: 402 QVMVTDS---ISNDTASINISVEDVNEWEPRF 430
+V+ +D+ + T+++ I V DVN+ P F
Sbjct: 964 RVVASDAGTPTKSSTSTLTIHVLDVNDETPTF 995
Score = 64.1 bits (149), Expect = 2e-09
Identities = 53/222 (23%), Positives = 94/222 (42%), Gaps = 10/222 (4%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVL-PGP 152
V + V DVNDN P ++ Y + E +D D P P++ + Y+++
Sbjct: 547 VRINVLDVNDNVPTFQKDAYVGALRENEPSVTQLVRLRATDEDSP-PNNQITYSIVSASA 605
Query: 153 HSEYLGFE-NELEPIIVVKKPLDFETVNNFTIKLRV--QDQGSPPLYSDTTLQVTVLDAD 209
Y E +I V +PLD+E ++N I L V D G+PPL S + + V D +
Sbjct: 606 FGSYFDISLYEGYGVISVSRPLDYEQISNGLIYLTVMAMDAGNPPLNSTVPVTIEVFDEN 665
Query: 210 DQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVN 269
D P F+ Y + ++ G + ++ G + YS G + +N
Sbjct: 666 DNPPTFSKPAYFVSVVENIMAGATVLFLNATDLDRSREYG-QESIIYSLEGSTQ--FRIN 722
Query: 270 KDTGQVAATKQLIAELDPSVTIVLKATQ--VDNPDRYALATL 309
+G++ T L E ++++A V + + +AT+
Sbjct: 723 ARSGEITTTSLLDRETKSEYILIVRAVDGGVGHNQKTGIATV 764
Score = 62.1 bits (144), Expect = 9e-09
Identities = 90/364 (24%), Positives = 150/364 (41%), Gaps = 28/364 (7%)
Query: 85 TTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSAL 144
T S +++ V DVND P + A Y V VSE +D D G ++ L
Sbjct: 972 TPTKSSTSTLTIHVLDVNDETPTFFPAVYNVSVSEDVPREFRVVWLNCTDND-VGLNAEL 1030
Query: 145 HYAVLPG--PHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGS-PPLYSDT-T 200
Y + G +G+ + + +V LD ET + + L D G ++ T T
Sbjct: 1031 SYFITGGNVDGKFSVGYRDAVVRTVV---GLDRETTAAYMLILEAIDNGPVGKRHTGTAT 1087
Query: 201 LQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSST- 259
+ VTVLD +D P F Y A +P+D EG + + A D D G + Y
Sbjct: 1088 VFVTVLDVNDNRPIFLQSSYEASVPEDIPEGHSIL----QLKATDADEGEFGRVWYRILH 1143
Query: 260 GDHKQLIVVNKDTG-QVAATKQLIAELDPSVTIVLKATQVD-NPDRYALATLXXXXXXXX 317
G+H ++ G + + L E + S ++++A D P R ++ +
Sbjct: 1144 GNHGNNFRIHVSNGLLMRGPRPLDRERNSSHVLIVEAYNHDLGPMRSSVRVIVYVEDIND 1203
Query: 318 XXXXXXXXLQFTQKQYSTT-VSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDK 376
FTQ+QYS + E A G+ ++ + +++ + L Y K
Sbjct: 1204 EAPV------FTQQQYSRLGLRETAGIGTSVIVVQATDRDS--GDGGLVNYRILSGAEGK 1255
Query: 377 FAIN-NAGEVILRRSLDYETTSNYFYQVMVTDS---ISNDTASINISVEDVNEWEPRFRH 432
F I+ + G +I LDYET ++Y V TD + S+ I++ + + +F +
Sbjct: 1256 FEIDESTGLIITVNYLDYETKTSYMMNVSATDQAPPFNQGFCSVYITLLNELDEAVQFSN 1315
Query: 433 PQYE 436
YE
Sbjct: 1316 ASYE 1319
Score = 56.0 bits (129), Expect = 6e-07
Identities = 74/355 (20%), Positives = 144/355 (40%), Gaps = 30/355 (8%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
V + + + NDN P + Y + + E +D D G + Y P
Sbjct: 446 VKITLINENDNRPIFSQPLYNISLYENVTVGTSVLTVLATDNDA-GTFGEVSYFFSDDP- 503
Query: 154 SEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNP 213
+ + + I+++ + LD+E + FT+ + +D G + +++ VLD +D P
Sbjct: 504 -DRFSLDKDTGLIMLIAR-LDYELIQRFTLTIIARDGGGEE--TTGRVRINVLDVNDNVP 559
Query: 214 KFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQY-----SSTGDHKQLIVV 268
F + Y L ++ T L + A D+D N + Y S+ G + I +
Sbjct: 560 TFQKDAYVGALRENEPSVTQLVR----LRATDEDSPPNNQITYSIVSASAFGSYFD-ISL 614
Query: 269 NKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQF 328
+ G ++ ++ L E + I L +D + +T+ F
Sbjct: 615 YEGYGVISVSRPLDYEQISNGLIYLTVMAMDAGNPPLNSTVPVTIEVFDENDNPPT---F 671
Query: 329 TQKQYSTTVSEGASPGSVLLTL--TTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEV 385
++ Y +V E G+ +L L T + ++ E+ + + + + + +F IN +GE+
Sbjct: 672 SKPAYFVSVVENIMAGATVLFLNATDLDRSREYGQESIIYSLEGST---QFRINARSGEI 728
Query: 386 ILRRSLDYETTSNYFYQVMVTD-----SISNDTASINISVEDVNEWEPRFRHPQY 435
LD ET S Y V D + A++NI++ D+N+ P ++ Y
Sbjct: 729 TTTSLLDRETKSEYILIVRAVDGGVGHNQKTGIATVNITLLDINDNHPTWKDAPY 783
Score = 50.0 bits (114), Expect = 4e-05
Identities = 55/227 (24%), Positives = 92/227 (40%), Gaps = 12/227 (5%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRA---LDREE 67
+ ED P G I L + G + R+ N L+R LDRE
Sbjct: 1111 VPEDIPEGHSILQLKATDADEGEFGRVWYRILHGNHGNNFRIHVSNGLLMRGPRPLDRER 1170
Query: 68 KIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYA-VRVSETXXXXXX 126
S+V + V + V V V D+ND AP + Y+ + + ET
Sbjct: 1171 N--SSHVLI-VEAYNHDLGPMRSSVRVIVYVEDINDEAPVFTQQQYSRLGLRETAGIGTS 1227
Query: 127 XXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFE-NELEPIIVVKKPLDFETVNNFTIKL 185
+DRD G ++Y +L G + FE +E +I+ LD+ET ++ + +
Sbjct: 1228 VIVVQATDRDS-GDGGLVNYRILSGAEGK---FEIDESTGLIITVNYLDYETKTSYMMNV 1283
Query: 186 RVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGT 232
DQ P ++ +T+L+ D+ +F+ Y A + ++ GT
Sbjct: 1284 SATDQAPPFNQGFCSVYITLLNELDEAVQFSNASYEAAILENLALGT 1330
Score = 44.8 bits (101), Expect = 0.001
Identities = 36/111 (32%), Positives = 50/111 (45%), Gaps = 7/111 (6%)
Query: 328 FTQKQYST--TVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGE 384
FT + T +SE GS + L + + PL F VS FA+ + G
Sbjct: 31 FTNHFFDTYLLISEDTPVGSSVTQLLAQDMDND----PLVFGVSGEEASRFFAVEPDTGV 86
Query: 385 VILRRSLDYETTSNYFYQVMVTDSISNDTASINISVEDVNEWEPRFRHPQY 435
V LR+ LD ET S + + V+D T +NI V DVN+ P F + Y
Sbjct: 87 VWLRQPLDRETKSEFTVEFSVSDHQGVITRKVNIQVGDVNDNAPTFHNQPY 137
>BC032581-1|AAH32581.1| 1061|Homo sapiens CDH23 protein protein.
Length = 1061
Score = 92.3 bits (219), Expect = 7e-18
Identities = 102/440 (23%), Positives = 179/440 (40%), Gaps = 31/440 (7%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEKIG 70
ISEDTP+GS + L D D + +E + P + + L + LDRE K
Sbjct: 42 ISEDTPVGSSVTQLLAQ-DMDNDPLVFGVSGEEASRFFAVEPDTGVVWLRQPLDRETK-- 98
Query: 71 PSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXX 130
S V + V+++V DVNDNAP + PY+VR+ E
Sbjct: 99 -SEFTVEFSVSDHQGV---ITRKVNIQVGDVNDNAPTFHNQPYSVRIPENTPVGTPIFIV 154
Query: 131 XXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQ 190
+D D S L+ P S++ ++ I+ V + LD+ET + + + DQ
Sbjct: 155 NATDPDLGAGGSVLYSF---QPPSQFFAIDS-ARGIVTVIRELDYETTQAYQLTVNATDQ 210
Query: 191 G-SPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLG 249
+ PL + L + + D D +P F Y+ + + + GT + I+A DQD G
Sbjct: 211 DKTRPLSTLANLAIIITDVQDMDPIFINLPYSTNIYEHSPPGTTVRI----ITAIDQDKG 266
Query: 250 INAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAE---LDPSVTIVLKATQVDNPDRYA 305
+ Y+ +G+ + ++ +G + L E + +K T++ N DR
Sbjct: 267 RPRGIGYTIVSGNTNSIFALDYISGVLTLNGLLDRENPLYSHGFILTVKGTEL-NDDRTP 325
Query: 306 LATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVL-LTLTTVPQNTEF-RESP 363
+F +YS ++E A G L L + V ++ S
Sbjct: 326 SDATVTTTFNILVIDINDNAPEFNSSEYSVAITELAQVGFALPLFIQVVDKDENLGLNSM 385
Query: 364 LQFYV----SDRSFLDKFAINNAGEVILRRS--LDYETTSNYFYQVMVTDSISNDT--AS 415
+ Y+ S + ++ ++ +R + LDYET Y + + +S+ + A
Sbjct: 386 FEVYLVGNNSHHFIISPTSVQGKADIRIRVAIPLDYETVDRYDFDLFANESVPDHVGYAK 445
Query: 416 INISVEDVNEWEPRFRHPQY 435
+ I++ + N+ P F P Y
Sbjct: 446 VKITLINENDNRPIFSQPLY 465
Score = 82.6 bits (195), Expect = 6e-15
Identities = 104/480 (21%), Positives = 181/480 (37%), Gaps = 33/480 (6%)
Query: 57 LTLLRALDREEKIGPSNVYVNVRC----DRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAP 112
LTL LDRE + + V+ D R +D + ++ V D+NDNAP++ +
Sbjct: 293 LTLNGLLDRENPLYSHGFILTVKGTELNDDRTPSDATVTTTFNILVIDINDNAPEFNSSE 352
Query: 113 YAVRVSETXXXXXXX-XXXXXSDRDQPGPHSALHYAVLPGPHSEYL-----GFENELEPI 166
Y+V ++E D+D+ +++ L G +S + + + +
Sbjct: 353 YSVAITELAQVGFALPLFIQVVDKDENLGLNSMFEVYLVGNNSHHFIISPTSVQGKADIR 412
Query: 167 IVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPD 226
I V PLD+ETV+ + L ++ P +++T+++ +D P F+ Y L +
Sbjct: 413 IRVAIPLDYETVDRYDFDL-FANESVPDHVGYAKVKITLINENDNRPIFSQPLYNISLYE 471
Query: 227 DAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLIAELD 286
+ GT + T + A D D G + Y + D + + +KDTG + +L EL
Sbjct: 472 NVTVGTSVLT----VLATDNDAGTFGEVSYFFSDDPDRFSL-DKDTGLIMLIARLDYELI 526
Query: 287 PSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSV 346
T+ + A + + F + Y + E +
Sbjct: 527 QRFTLTIIARDGGGEETTGRVRINVLDVNDNVPT-------FQKDAYVGALRENEPSVTQ 579
Query: 347 LLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAIN---NAGEVILRRSLDYETTSN--YFY 401
L+ L +++ VS +F F I+ G + + R LDYE SN +
Sbjct: 580 LVRLRATDEDSPPNNQITYSIVSASAFGSYFDISLYEGYGVISVSRPLDYEQISNGLIYL 639
Query: 402 QVMVTDSIS---NDTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXX 458
VM D+ + N T + I V D N+ P F P Y
Sbjct: 640 TVMAMDAGNPPLNSTVPVTIEVFDENDNPPTFSKPAYFVSVVENIMAGATVLFLNATDLD 699
Query: 459 VAHDGDAGTLALSLAGQHARMFYINASGDLFLREEAIGNLNSSSLHLVATAIDSGIPPRQ 518
+ + ++ SL G + F INA + S L+ A+D G+ Q
Sbjct: 700 RSREYGQESIIYSLEG--STQFRINARSGEITTTSLLDRETKSEYILIVRAVDGGVGHNQ 757
Score = 66.5 bits (155), Expect = 4e-10
Identities = 83/392 (21%), Positives = 146/392 (37%), Gaps = 17/392 (4%)
Query: 48 VGIVPGSKNLTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQ 107
+ + G +++ R LD E+ I +Y+ V + +PV++ V+D NDN P
Sbjct: 612 ISLYEGYGVISVSRPLDYEQ-ISNGLIYLTVMAMDAGNPPLNSTVPVTIEVFDENDNPPT 670
Query: 108 WEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPII 167
+ Y V V E +D D+ + +++ N I
Sbjct: 671 FSKPAYFVSVVENIMAGATVLFLNATDLDRSREYG--QESIIYSLEGSTQFRINARSGEI 728
Query: 168 VVKKPLDFETVNNFTIKLRVQD--QGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLP 225
LD ET + + + +R D G T+ +T+LD +D +P + Y L
Sbjct: 729 TTTSLLDRETKSEYILIVRAVDGGVGHNQKTGIATVNITLLDINDNHPTWKDAPYYINLV 788
Query: 226 DDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLI--A 283
+ + +TT + A D DLG N L YS +K +N TG++ T ++
Sbjct: 789 EMTPPDSDVTT----VVAVDPDLGENGTLVYSIQPPNK-FYSLNSTTGKIRTTHAMLDRE 843
Query: 284 ELDPSVTIVLKATQVDNPD--RYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGA 341
DP +++ V D R L F + V EG
Sbjct: 844 NPDPHEAELMRKIVVSVTDCGRPPLKATSSATVFVNLLDLNDNDPTFQNLPFVAEVLEGI 903
Query: 342 SPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFY 401
G + + + + +D +++G V+ LD E + Y
Sbjct: 904 PAGVSIYQVVAIDLDEGLNGLVSYRMPVGMPRMDFLINSSSGVVVTTTELDRERIAEYQL 963
Query: 402 QVMVTDS---ISNDTASINISVEDVNEWEPRF 430
+V+ +D+ + T+++ I V DVN+ P F
Sbjct: 964 RVVASDAGTPTKSSTSTLTIHVLDVNDETPTF 995
Score = 66.5 bits (155), Expect = 4e-10
Identities = 45/168 (26%), Positives = 75/168 (44%), Gaps = 8/168 (4%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPG-P 152
V V + D+NDN P ++ P+ V E D D+ G + + Y + G P
Sbjct: 876 VFVNLLDLNDNDPTFQNLPFVAEVLEGIPAGVSIYQVVAIDLDE-GLNGLVSYRMPVGMP 934
Query: 153 HSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQN 212
++L N ++V LD E + + +++ D G+P S +TL + VLD +D+
Sbjct: 935 RMDFL--INSSSGVVVTTTELDRERIAEYQLRVVASDAGTPTKSSTSTLTIHVLDVNDET 992
Query: 213 PKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTG 260
P F Y + +D + ++ D D+G+NA L Y TG
Sbjct: 993 PTFFPAVYNVSVSEDVPREFRVVW----LNCTDNDVGLNAELSYFITG 1036
Score = 64.1 bits (149), Expect = 2e-09
Identities = 53/222 (23%), Positives = 94/222 (42%), Gaps = 10/222 (4%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVL-PGP 152
V + V DVNDN P ++ Y + E +D D P P++ + Y+++
Sbjct: 547 VRINVLDVNDNVPTFQKDAYVGALRENEPSVTQLVRLRATDEDSP-PNNQITYSIVSASA 605
Query: 153 HSEYLGFE-NELEPIIVVKKPLDFETVNNFTIKLRV--QDQGSPPLYSDTTLQVTVLDAD 209
Y E +I V +PLD+E ++N I L V D G+PPL S + + V D +
Sbjct: 606 FGSYFDISLYEGYGVISVSRPLDYEQISNGLIYLTVMAMDAGNPPLNSTVPVTIEVFDEN 665
Query: 210 DQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVN 269
D P F+ Y + ++ G + ++ G + YS G + +N
Sbjct: 666 DNPPTFSKPAYFVSVVENIMAGATVLFLNATDLDRSREYG-QESIIYSLEGSTQ--FRIN 722
Query: 270 KDTGQVAATKQLIAELDPSVTIVLKATQ--VDNPDRYALATL 309
+G++ T L E ++++A V + + +AT+
Sbjct: 723 ARSGEITTTSLLDRETKSEYILIVRAVDGGVGHNQKTGIATV 764
Score = 56.0 bits (129), Expect = 6e-07
Identities = 74/355 (20%), Positives = 144/355 (40%), Gaps = 30/355 (8%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
V + + + NDN P + Y + + E +D D G + Y P
Sbjct: 446 VKITLINENDNRPIFSQPLYNISLYENVTVGTSVLTVLATDNDA-GTFGEVSYFFSDDP- 503
Query: 154 SEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNP 213
+ + + I+++ + LD+E + FT+ + +D G + +++ VLD +D P
Sbjct: 504 -DRFSLDKDTGLIMLIAR-LDYELIQRFTLTIIARDGGGEE--TTGRVRINVLDVNDNVP 559
Query: 214 KFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQY-----SSTGDHKQLIVV 268
F + Y L ++ T L + A D+D N + Y S+ G + I +
Sbjct: 560 TFQKDAYVGALRENEPSVTQLVR----LRATDEDSPPNNQITYSIVSASAFGSYFD-ISL 614
Query: 269 NKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQF 328
+ G ++ ++ L E + I L +D + +T+ F
Sbjct: 615 YEGYGVISVSRPLDYEQISNGLIYLTVMAMDAGNPPLNSTVPVTIEVFDENDNPPT---F 671
Query: 329 TQKQYSTTVSEGASPGSVLLTL--TTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEV 385
++ Y +V E G+ +L L T + ++ E+ + + + + + +F IN +GE+
Sbjct: 672 SKPAYFVSVVENIMAGATVLFLNATDLDRSREYGQESIIYSLEGST---QFRINARSGEI 728
Query: 386 ILRRSLDYETTSNYFYQVMVTD-----SISNDTASINISVEDVNEWEPRFRHPQY 435
LD ET S Y V D + A++NI++ D+N+ P ++ Y
Sbjct: 729 TTTSLLDRETKSEYILIVRAVDGGVGHNQKTGIATVNITLLDINDNHPTWKDAPY 783
Score = 44.8 bits (101), Expect = 0.001
Identities = 36/111 (32%), Positives = 50/111 (45%), Gaps = 7/111 (6%)
Query: 328 FTQKQYST--TVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGE 384
FT + T +SE GS + L + + PL F VS FA+ + G
Sbjct: 31 FTNHFFDTYLLISEDTPVGSSVTQLLAQDMDND----PLVFGVSGEEASRFFAVEPDTGV 86
Query: 385 VILRRSLDYETTSNYFYQVMVTDSISNDTASINISVEDVNEWEPRFRHPQY 435
V LR+ LD ET S + + V+D T +NI V DVN+ P F + Y
Sbjct: 87 VWLRQPLDRETKSEFTVEFSVSDHQGVITRKVNIQVGDVNDNAPTFHNQPY 137
>BC011570-1|AAH11570.1| 530|Homo sapiens cadherin-like 23 protein.
Length = 530
Score = 92.3 bits (219), Expect = 7e-18
Identities = 102/440 (23%), Positives = 179/440 (40%), Gaps = 31/440 (7%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEKIG 70
ISEDTP+GS + L D D + +E + P + + L + LDRE K
Sbjct: 42 ISEDTPVGSSVTQLLAQ-DMDNDPLVFGVSGEEASRFFAVEPDTGVVWLRQPLDRETK-- 98
Query: 71 PSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXX 130
S V + V+++V DVNDNAP + PY+VR+ E
Sbjct: 99 -SEFTVEFSVSDHQGV---ITRKVNIQVGDVNDNAPTFHNQPYSVRIPENTPVGTPIFIV 154
Query: 131 XXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQ 190
+D D S L+ P S++ ++ I+ V + LD+ET + + + DQ
Sbjct: 155 NATDPDLGAGGSVLYSF---QPPSQFFAIDS-ARGIVTVIRELDYETTQAYQLTVNATDQ 210
Query: 191 G-SPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLG 249
+ PL + L + + D D +P F Y+ + + + GT + I+A DQD G
Sbjct: 211 DKTRPLSTLANLAIIITDVQDMDPIFINLPYSTNIYEHSPPGTTVRI----ITAIDQDKG 266
Query: 250 INAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAE---LDPSVTIVLKATQVDNPDRYA 305
+ Y+ +G+ + ++ +G + L E + +K T++ N DR
Sbjct: 267 RPRGIGYTIVSGNTNSIFALDYISGVLTLNGLLDRENPLYSHGFILTVKGTEL-NDDRTP 325
Query: 306 LATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVL-LTLTTVPQNTEF-RESP 363
+F +YS ++E A G L L + V ++ S
Sbjct: 326 SDATVTTTFNILVIDINDNAPEFNSSEYSVAITELAQVGFALPLFIQVVDKDENLGLNSM 385
Query: 364 LQFYV----SDRSFLDKFAINNAGEVILRRS--LDYETTSNYFYQVMVTDSISNDT--AS 415
+ Y+ S + ++ ++ +R + LDYET Y + + +S+ + A
Sbjct: 386 FEVYLVGNNSHHFIISPTSVQGKADIRIRVAIPLDYETVDRYDFDLFANESVPDHVGYAK 445
Query: 416 INISVEDVNEWEPRFRHPQY 435
+ I++ + N+ P F P Y
Sbjct: 446 VKITLINENDNRPIFSQPLY 465
Score = 44.8 bits (101), Expect = 0.001
Identities = 36/111 (32%), Positives = 50/111 (45%), Gaps = 7/111 (6%)
Query: 328 FTQKQYST--TVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGE 384
FT + T +SE GS + L + + PL F VS FA+ + G
Sbjct: 31 FTNHFFDTYLLISEDTPVGSSVTQLLAQDMDND----PLVFGVSGEEASRFFAVEPDTGV 86
Query: 385 VILRRSLDYETTSNYFYQVMVTDSISNDTASINISVEDVNEWEPRFRHPQY 435
V LR+ LD ET S + + V+D T +NI V DVN+ P F + Y
Sbjct: 87 VWLRQPLDRETKSEFTVEFSVSDHQGVITRKVNIQVGDVNDNAPTFHNQPY 137
>AY358617-1|AAQ88980.1| 530|Homo sapiens CDH23 protein.
Length = 530
Score = 92.3 bits (219), Expect = 7e-18
Identities = 102/440 (23%), Positives = 179/440 (40%), Gaps = 31/440 (7%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEKIG 70
ISEDTP+GS + L D D + +E + P + + L + LDRE K
Sbjct: 42 ISEDTPVGSSVTQLLAQ-DMDNDPLVFGVSGEEASRFFAVEPDTGVVWLRQPLDRETK-- 98
Query: 71 PSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXX 130
S V + V+++V DVNDNAP + PY+VR+ E
Sbjct: 99 -SEFTVEFSVSDHQGV---ITRKVNIQVGDVNDNAPTFHNQPYSVRIPENTPVGTPIFIV 154
Query: 131 XXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQ 190
+D D S L+ P S++ ++ I+ V + LD+ET + + + DQ
Sbjct: 155 NATDPDLGAGGSVLYSF---QPPSQFFAIDS-ARGIVTVIRELDYETTQAYQLTVNATDQ 210
Query: 191 G-SPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLG 249
+ PL + L + + D D +P F Y+ + + + GT + I+A DQD G
Sbjct: 211 DKTRPLSTLANLAIIITDVQDMDPIFINLPYSTNIYEHSPPGTTVRI----ITAIDQDKG 266
Query: 250 INAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAE---LDPSVTIVLKATQVDNPDRYA 305
+ Y+ +G+ + ++ +G + L E + +K T++ N DR
Sbjct: 267 RPRGIGYTIVSGNTNSIFALDYISGVLTLNGLLDRENPLYSHGFILTVKGTEL-NDDRTP 325
Query: 306 LATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVL-LTLTTVPQNTEF-RESP 363
+F +YS ++E A G L L + V ++ S
Sbjct: 326 SDATVTTTFNILVIDINDNAPEFNSSEYSVAITELAQVGFALPLFIQVVDKDENLGLNSM 385
Query: 364 LQFYV----SDRSFLDKFAINNAGEVILRRS--LDYETTSNYFYQVMVTDSISNDT--AS 415
+ Y+ S + ++ ++ +R + LDYET Y + + +S+ + A
Sbjct: 386 FEVYLVGNNSHHFIISPTSVQGKADIRIRVAIPLDYETVDRYDFDLFANESVPDHVGYAK 445
Query: 416 INISVEDVNEWEPRFRHPQY 435
+ I++ + N+ P F P Y
Sbjct: 446 VKITLINENDNRPIFSQPLY 465
Score = 44.8 bits (101), Expect = 0.001
Identities = 36/111 (32%), Positives = 50/111 (45%), Gaps = 7/111 (6%)
Query: 328 FTQKQYST--TVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGE 384
FT + T +SE GS + L + + PL F VS FA+ + G
Sbjct: 31 FTNHFFDTYLLISEDTPVGSSVTQLLAQDMDND----PLVFGVSGEEASRFFAVEPDTGV 86
Query: 385 VILRRSLDYETTSNYFYQVMVTDSISNDTASINISVEDVNEWEPRFRHPQY 435
V LR+ LD ET S + + V+D T +NI V DVN+ P F + Y
Sbjct: 87 VWLRQPLDRETKSEFTVEFSVSDHQGVITRKVNIQVGDVNDNAPTFHNQPY 137
>AL772287-1|CAI13625.2| 1066|Homo sapiens cadherin-like 23 protein.
Length = 1066
Score = 92.3 bits (219), Expect = 7e-18
Identities = 102/442 (23%), Positives = 174/442 (39%), Gaps = 30/442 (6%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEKIG 70
ISEDTP+GS + L D D + +E + P + + L + LDRE K
Sbjct: 42 ISEDTPVGSSVTQLLAQ-DMDNDPLVFGVSGEEASRFFAVEPDTGVVWLRQPLDRETK-- 98
Query: 71 PSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXX 130
S V + V+++V DVNDNAP + PY+VR+ E
Sbjct: 99 -SEFTVEFSVSDHQGV---ITRKVNIQVGDVNDNAPTFHNQPYSVRIPEVGATGNTPVGT 154
Query: 131 XXSDRDQPGPHSALHYAVLPG--PHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQ 188
+ P +VL P S++ ++ I+ V + LD+ET + + +
Sbjct: 155 PIFIVNATDPDLGAGGSVLYSFQPPSQFFAIDS-ARGIVTVIRELDYETTQAYQLTVNAT 213
Query: 189 DQG-SPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQD 247
DQ + PL + L + + D D +P F Y+ + + + GT + I+A DQD
Sbjct: 214 DQDKTRPLSTLANLAIIITDVQDMDPIFINLPYSTNIYEHSPPGTTVRI----ITAIDQD 269
Query: 248 LGINAPLQY---SSTGDHKQLIVVNKDTGQVAATKQLIAE---LDPSVTIVLKATQVDNP 301
G + Y S G+ + ++ +G + L E + +K T++ N
Sbjct: 270 KGRPRGIGYTIVSVAGNTNSIFALDYISGVLTLNGLLDRENPLYSHGFILTVKGTEL-ND 328
Query: 302 DRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRE 361
DR +F +YS ++E A G L V E
Sbjct: 329 DRTPSDATVTTTFNILVIDINDNAPEFNSSEYSVAITELAQVGFALPLFIQVVDKDEGLN 388
Query: 362 SPLQFYV----SDRSFLDKFAINNAGEVILRRS--LDYETTSNYFYQVMVTDSISNDT-- 413
S + Y+ S + ++ ++ +R + LDYET Y + + +S+ +
Sbjct: 389 SMFEVYLVGNNSHHFIISPTSVQGKADIRIRVAIPLDYETVDRYDFDLFANESVPDHVGY 448
Query: 414 ASINISVEDVNEWEPRFRHPQY 435
A + I++ + N+ P F P Y
Sbjct: 449 AKVKITLINENDNRPIFSQPLY 470
Score = 80.6 bits (190), Expect = 2e-14
Identities = 106/480 (22%), Positives = 181/480 (37%), Gaps = 35/480 (7%)
Query: 57 LTLLRALDREEKIGPSNVYVNVRC----DRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAP 112
LTL LDRE + + V+ D R +D + ++ V D+NDNAP++ +
Sbjct: 300 LTLNGLLDRENPLYSHGFILTVKGTELNDDRTPSDATVTTTFNILVIDINDNAPEFNSSE 359
Query: 113 YAVRVSETXXXXXXX-XXXXXSDRDQPGPHSALHYAVLPGPHSEYL-----GFENELEPI 166
Y+V ++E D+D+ G +S L G +S + + + +
Sbjct: 360 YSVAITELAQVGFALPLFIQVVDKDE-GLNSMFE-VYLVGNNSHHFIISPTSVQGKADIR 417
Query: 167 IVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPD 226
I V PLD+ETV+ + L ++ P +++T+++ +D P F+ Y L +
Sbjct: 418 IRVAIPLDYETVDRYDFDL-FANESVPDHVGYAKVKITLINENDNRPIFSQPLYNISLYE 476
Query: 227 DAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLIAELD 286
+ GT + T + A D D G + Y + D + + +KDTG + +L EL
Sbjct: 477 NVTVGTSVLT----VLATDNDAGTFGEVSYFFSDDPDRFSL-DKDTGLIMLIARLDYELI 531
Query: 287 PSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSV 346
T+ + A + + F + Y + E +
Sbjct: 532 QRFTLTIIARDGGGEETTGRVRINVLDVNDNVPT-------FQKDAYVGALRENEPSVTQ 584
Query: 347 LLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAIN---NAGEVILRRSLDYETTSN--YFY 401
L+ L +++ VS +F F I+ G + + R LDYE SN +
Sbjct: 585 LVRLRATDEDSPPNNQITYSIVSASAFGSYFDISLYEGYGVISVSRPLDYEQISNGLIYL 644
Query: 402 QVMVTDSIS---NDTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXX 458
VM D+ + N T + I V D N+ P F P Y
Sbjct: 645 TVMAMDAGNPPLNSTVPVTIEVFDENDNPPTFSKPAYFVSVVENIMAGATVLFLNATDLD 704
Query: 459 VAHDGDAGTLALSLAGQHARMFYINASGDLFLREEAIGNLNSSSLHLVATAIDSGIPPRQ 518
+ + ++ SL G + F INA + S L+ A+D G+ Q
Sbjct: 705 RSREYGQESIIYSLEG--STQFRINARSGEITTTSLLDRETKSEYILIVRAVDGGVGHNQ 762
Score = 66.5 bits (155), Expect = 4e-10
Identities = 83/392 (21%), Positives = 146/392 (37%), Gaps = 17/392 (4%)
Query: 48 VGIVPGSKNLTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQ 107
+ + G +++ R LD E+ I +Y+ V + +PV++ V+D NDN P
Sbjct: 617 ISLYEGYGVISVSRPLDYEQ-ISNGLIYLTVMAMDAGNPPLNSTVPVTIEVFDENDNPPT 675
Query: 108 WEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPII 167
+ Y V V E +D D+ + +++ N I
Sbjct: 676 FSKPAYFVSVVENIMAGATVLFLNATDLDRSREYG--QESIIYSLEGSTQFRINARSGEI 733
Query: 168 VVKKPLDFETVNNFTIKLRVQD--QGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLP 225
LD ET + + + +R D G T+ +T+LD +D +P + Y L
Sbjct: 734 TTTSLLDRETKSEYILIVRAVDGGVGHNQKTGIATVNITLLDINDNHPTWKDAPYYINLV 793
Query: 226 DDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLI--A 283
+ + +TT + A D DLG N L YS +K +N TG++ T ++
Sbjct: 794 EMTPPDSDVTT----VVAVDPDLGENGTLVYSIQPPNK-FYSLNSTTGKIRTTHAMLDRE 848
Query: 284 ELDPSVTIVLKATQVDNPD--RYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGA 341
DP +++ V D R L F + V EG
Sbjct: 849 NPDPHEAELMRKIVVSVTDCGRPPLKATSSATVFVNLLDLNDNDPTFQNLPFVAEVLEGI 908
Query: 342 SPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFY 401
G + + + + +D +++G V+ LD E + Y
Sbjct: 909 PAGVSIYQVVAIDLDEGLNGLVSYRMPVGMPRMDFLINSSSGVVVTTTELDRERIAEYQL 968
Query: 402 QVMVTDS---ISNDTASINISVEDVNEWEPRF 430
+V+ +D+ + T+++ I V DVN+ P F
Sbjct: 969 RVVASDAGTPTKSSTSTLTIHVLDVNDETPTF 1000
Score = 66.5 bits (155), Expect = 4e-10
Identities = 45/168 (26%), Positives = 75/168 (44%), Gaps = 8/168 (4%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPG-P 152
V V + D+NDN P ++ P+ V E D D+ G + + Y + G P
Sbjct: 881 VFVNLLDLNDNDPTFQNLPFVAEVLEGIPAGVSIYQVVAIDLDE-GLNGLVSYRMPVGMP 939
Query: 153 HSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQN 212
++L N ++V LD E + + +++ D G+P S +TL + VLD +D+
Sbjct: 940 RMDFL--INSSSGVVVTTTELDRERIAEYQLRVVASDAGTPTKSSTSTLTIHVLDVNDET 997
Query: 213 PKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTG 260
P F Y + +D + ++ D D+G+NA L Y TG
Sbjct: 998 PTFFPAVYNVSVSEDVPREFRVVW----LNCTDNDVGLNAELSYFITG 1041
Score = 64.1 bits (149), Expect = 2e-09
Identities = 53/222 (23%), Positives = 94/222 (42%), Gaps = 10/222 (4%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVL-PGP 152
V + V DVNDN P ++ Y + E +D D P P++ + Y+++
Sbjct: 552 VRINVLDVNDNVPTFQKDAYVGALRENEPSVTQLVRLRATDEDSP-PNNQITYSIVSASA 610
Query: 153 HSEYLGFE-NELEPIIVVKKPLDFETVNNFTIKLRV--QDQGSPPLYSDTTLQVTVLDAD 209
Y E +I V +PLD+E ++N I L V D G+PPL S + + V D +
Sbjct: 611 FGSYFDISLYEGYGVISVSRPLDYEQISNGLIYLTVMAMDAGNPPLNSTVPVTIEVFDEN 670
Query: 210 DQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVN 269
D P F+ Y + ++ G + ++ G + YS G + +N
Sbjct: 671 DNPPTFSKPAYFVSVVENIMAGATVLFLNATDLDRSREYG-QESIIYSLEGSTQ--FRIN 727
Query: 270 KDTGQVAATKQLIAELDPSVTIVLKATQ--VDNPDRYALATL 309
+G++ T L E ++++A V + + +AT+
Sbjct: 728 ARSGEITTTSLLDRETKSEYILIVRAVDGGVGHNQKTGIATV 769
Score = 56.0 bits (129), Expect = 6e-07
Identities = 74/355 (20%), Positives = 144/355 (40%), Gaps = 30/355 (8%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
V + + + NDN P + Y + + E +D D G + Y P
Sbjct: 451 VKITLINENDNRPIFSQPLYNISLYENVTVGTSVLTVLATDNDA-GTFGEVSYFFSDDP- 508
Query: 154 SEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNP 213
+ + + I+++ + LD+E + FT+ + +D G + +++ VLD +D P
Sbjct: 509 -DRFSLDKDTGLIMLIAR-LDYELIQRFTLTIIARDGGGEE--TTGRVRINVLDVNDNVP 564
Query: 214 KFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQY-----SSTGDHKQLIVV 268
F + Y L ++ T L + A D+D N + Y S+ G + I +
Sbjct: 565 TFQKDAYVGALRENEPSVTQLVR----LRATDEDSPPNNQITYSIVSASAFGSYFD-ISL 619
Query: 269 NKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQF 328
+ G ++ ++ L E + I L +D + +T+ F
Sbjct: 620 YEGYGVISVSRPLDYEQISNGLIYLTVMAMDAGNPPLNSTVPVTIEVFDENDNPPT---F 676
Query: 329 TQKQYSTTVSEGASPGSVLLTL--TTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEV 385
++ Y +V E G+ +L L T + ++ E+ + + + + + +F IN +GE+
Sbjct: 677 SKPAYFVSVVENIMAGATVLFLNATDLDRSREYGQESIIYSLEGST---QFRINARSGEI 733
Query: 386 ILRRSLDYETTSNYFYQVMVTD-----SISNDTASINISVEDVNEWEPRFRHPQY 435
LD ET S Y V D + A++NI++ D+N+ P ++ Y
Sbjct: 734 TTTSLLDRETKSEYILIVRAVDGGVGHNQKTGIATVNITLLDINDNHPTWKDAPY 788
Score = 44.8 bits (101), Expect = 0.001
Identities = 36/111 (32%), Positives = 50/111 (45%), Gaps = 7/111 (6%)
Query: 328 FTQKQYST--TVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGE 384
FT + T +SE GS + L + + PL F VS FA+ + G
Sbjct: 31 FTNHFFDTYLLISEDTPVGSSVTQLLAQDMDND----PLVFGVSGEEASRFFAVEPDTGV 86
Query: 385 VILRRSLDYETTSNYFYQVMVTDSISNDTASINISVEDVNEWEPRFRHPQY 435
V LR+ LD ET S + + V+D T +NI V DVN+ P F + Y
Sbjct: 87 VWLRQPLDRETKSEFTVEFSVSDHQGVITRKVNIQVGDVNDNAPTFHNQPY 137
>AL731541-5|CAM20296.1| 1066|Homo sapiens cadherin-like 23 protein.
Length = 1066
Score = 92.3 bits (219), Expect = 7e-18
Identities = 102/442 (23%), Positives = 174/442 (39%), Gaps = 30/442 (6%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEKIG 70
ISEDTP+GS + L D D + +E + P + + L + LDRE K
Sbjct: 42 ISEDTPVGSSVTQLLAQ-DMDNDPLVFGVSGEEASRFFAVEPDTGVVWLRQPLDRETK-- 98
Query: 71 PSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXX 130
S V + V+++V DVNDNAP + PY+VR+ E
Sbjct: 99 -SEFTVEFSVSDHQGV---ITRKVNIQVGDVNDNAPTFHNQPYSVRIPEVGATGNTPVGT 154
Query: 131 XXSDRDQPGPHSALHYAVLPG--PHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQ 188
+ P +VL P S++ ++ I+ V + LD+ET + + +
Sbjct: 155 PIFIVNATDPDLGAGGSVLYSFQPPSQFFAIDS-ARGIVTVIRELDYETTQAYQLTVNAT 213
Query: 189 DQG-SPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQD 247
DQ + PL + L + + D D +P F Y+ + + + GT + I+A DQD
Sbjct: 214 DQDKTRPLSTLANLAIIITDVQDMDPIFINLPYSTNIYEHSPPGTTVRI----ITAIDQD 269
Query: 248 LGINAPLQY---SSTGDHKQLIVVNKDTGQVAATKQLIAE---LDPSVTIVLKATQVDNP 301
G + Y S G+ + ++ +G + L E + +K T++ N
Sbjct: 270 KGRPRGIGYTIVSVAGNTNSIFALDYISGVLTLNGLLDRENPLYSHGFILTVKGTEL-ND 328
Query: 302 DRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRE 361
DR +F +YS ++E A G L V E
Sbjct: 329 DRTPSDATVTTTFNILVIDINDNAPEFNSSEYSVAITELAQVGFALPLFIQVVDKDEGLN 388
Query: 362 SPLQFYV----SDRSFLDKFAINNAGEVILRRS--LDYETTSNYFYQVMVTDSISNDT-- 413
S + Y+ S + ++ ++ +R + LDYET Y + + +S+ +
Sbjct: 389 SMFEVYLVGNNSHHFIISPTSVQGKADIRIRVAIPLDYETVDRYDFDLFANESVPDHVGY 448
Query: 414 ASINISVEDVNEWEPRFRHPQY 435
A + I++ + N+ P F P Y
Sbjct: 449 AKVKITLINENDNRPIFSQPLY 470
Score = 80.6 bits (190), Expect = 2e-14
Identities = 106/480 (22%), Positives = 181/480 (37%), Gaps = 35/480 (7%)
Query: 57 LTLLRALDREEKIGPSNVYVNVRC----DRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAP 112
LTL LDRE + + V+ D R +D + ++ V D+NDNAP++ +
Sbjct: 300 LTLNGLLDRENPLYSHGFILTVKGTELNDDRTPSDATVTTTFNILVIDINDNAPEFNSSE 359
Query: 113 YAVRVSETXXXXXXX-XXXXXSDRDQPGPHSALHYAVLPGPHSEYL-----GFENELEPI 166
Y+V ++E D+D+ G +S L G +S + + + +
Sbjct: 360 YSVAITELAQVGFALPLFIQVVDKDE-GLNSMFE-VYLVGNNSHHFIISPTSVQGKADIR 417
Query: 167 IVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPD 226
I V PLD+ETV+ + L ++ P +++T+++ +D P F+ Y L +
Sbjct: 418 IRVAIPLDYETVDRYDFDL-FANESVPDHVGYAKVKITLINENDNRPIFSQPLYNISLYE 476
Query: 227 DAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLIAELD 286
+ GT + T + A D D G + Y + D + + +KDTG + +L EL
Sbjct: 477 NVTVGTSVLT----VLATDNDAGTFGEVSYFFSDDPDRFSL-DKDTGLIMLIARLDYELI 531
Query: 287 PSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSV 346
T+ + A + + F + Y + E +
Sbjct: 532 QRFTLTIIARDGGGEETTGRVRINVLDVNDNVPT-------FQKDAYVGALRENEPSVTQ 584
Query: 347 LLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAIN---NAGEVILRRSLDYETTSN--YFY 401
L+ L +++ VS +F F I+ G + + R LDYE SN +
Sbjct: 585 LVRLRATDEDSPPNNQITYSIVSASAFGSYFDISLYEGYGVISVSRPLDYEQISNGLIYL 644
Query: 402 QVMVTDSIS---NDTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXX 458
VM D+ + N T + I V D N+ P F P Y
Sbjct: 645 TVMAMDAGNPPLNSTVPVTIEVFDENDNPPTFSKPAYFVSVVENIMAGATVLFLNATDLD 704
Query: 459 VAHDGDAGTLALSLAGQHARMFYINASGDLFLREEAIGNLNSSSLHLVATAIDSGIPPRQ 518
+ + ++ SL G + F INA + S L+ A+D G+ Q
Sbjct: 705 RSREYGQESIIYSLEG--STQFRINARSGEITTTSLLDRETKSEYILIVRAVDGGVGHNQ 762
Score = 66.5 bits (155), Expect = 4e-10
Identities = 83/392 (21%), Positives = 146/392 (37%), Gaps = 17/392 (4%)
Query: 48 VGIVPGSKNLTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQ 107
+ + G +++ R LD E+ I +Y+ V + +PV++ V+D NDN P
Sbjct: 617 ISLYEGYGVISVSRPLDYEQ-ISNGLIYLTVMAMDAGNPPLNSTVPVTIEVFDENDNPPT 675
Query: 108 WEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPII 167
+ Y V V E +D D+ + +++ N I
Sbjct: 676 FSKPAYFVSVVENIMAGATVLFLNATDLDRSREYG--QESIIYSLEGSTQFRINARSGEI 733
Query: 168 VVKKPLDFETVNNFTIKLRVQD--QGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLP 225
LD ET + + + +R D G T+ +T+LD +D +P + Y L
Sbjct: 734 TTTSLLDRETKSEYILIVRAVDGGVGHNQKTGIATVNITLLDINDNHPTWKDAPYYINLV 793
Query: 226 DDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLI--A 283
+ + +TT + A D DLG N L YS +K +N TG++ T ++
Sbjct: 794 EMTPPDSDVTT----VVAVDPDLGENGTLVYSIQPPNK-FYSLNSTTGKIRTTHAMLDRE 848
Query: 284 ELDPSVTIVLKATQVDNPD--RYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGA 341
DP +++ V D R L F + V EG
Sbjct: 849 NPDPHEAELMRKIVVSVTDCGRPPLKATSSATVFVNLLDLNDNDPTFQNLPFVAEVLEGI 908
Query: 342 SPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFY 401
G + + + + +D +++G V+ LD E + Y
Sbjct: 909 PAGVSIYQVVAIDLDEGLNGLVSYRMPVGMPRMDFLINSSSGVVVTTTELDRERIAEYQL 968
Query: 402 QVMVTDS---ISNDTASINISVEDVNEWEPRF 430
+V+ +D+ + T+++ I V DVN+ P F
Sbjct: 969 RVVASDAGTPTKSSTSTLTIHVLDVNDETPTF 1000
Score = 66.5 bits (155), Expect = 4e-10
Identities = 45/168 (26%), Positives = 75/168 (44%), Gaps = 8/168 (4%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPG-P 152
V V + D+NDN P ++ P+ V E D D+ G + + Y + G P
Sbjct: 881 VFVNLLDLNDNDPTFQNLPFVAEVLEGIPAGVSIYQVVAIDLDE-GLNGLVSYRMPVGMP 939
Query: 153 HSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQN 212
++L N ++V LD E + + +++ D G+P S +TL + VLD +D+
Sbjct: 940 RMDFL--INSSSGVVVTTTELDRERIAEYQLRVVASDAGTPTKSSTSTLTIHVLDVNDET 997
Query: 213 PKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTG 260
P F Y + +D + ++ D D+G+NA L Y TG
Sbjct: 998 PTFFPAVYNVSVSEDVPREFRVVW----LNCTDNDVGLNAELSYFITG 1041
Score = 64.1 bits (149), Expect = 2e-09
Identities = 53/222 (23%), Positives = 94/222 (42%), Gaps = 10/222 (4%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVL-PGP 152
V + V DVNDN P ++ Y + E +D D P P++ + Y+++
Sbjct: 552 VRINVLDVNDNVPTFQKDAYVGALRENEPSVTQLVRLRATDEDSP-PNNQITYSIVSASA 610
Query: 153 HSEYLGFE-NELEPIIVVKKPLDFETVNNFTIKLRV--QDQGSPPLYSDTTLQVTVLDAD 209
Y E +I V +PLD+E ++N I L V D G+PPL S + + V D +
Sbjct: 611 FGSYFDISLYEGYGVISVSRPLDYEQISNGLIYLTVMAMDAGNPPLNSTVPVTIEVFDEN 670
Query: 210 DQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVN 269
D P F+ Y + ++ G + ++ G + YS G + +N
Sbjct: 671 DNPPTFSKPAYFVSVVENIMAGATVLFLNATDLDRSREYG-QESIIYSLEGSTQ--FRIN 727
Query: 270 KDTGQVAATKQLIAELDPSVTIVLKATQ--VDNPDRYALATL 309
+G++ T L E ++++A V + + +AT+
Sbjct: 728 ARSGEITTTSLLDRETKSEYILIVRAVDGGVGHNQKTGIATV 769
Score = 56.0 bits (129), Expect = 6e-07
Identities = 74/355 (20%), Positives = 144/355 (40%), Gaps = 30/355 (8%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
V + + + NDN P + Y + + E +D D G + Y P
Sbjct: 451 VKITLINENDNRPIFSQPLYNISLYENVTVGTSVLTVLATDNDA-GTFGEVSYFFSDDP- 508
Query: 154 SEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNP 213
+ + + I+++ + LD+E + FT+ + +D G + +++ VLD +D P
Sbjct: 509 -DRFSLDKDTGLIMLIAR-LDYELIQRFTLTIIARDGGGEE--TTGRVRINVLDVNDNVP 564
Query: 214 KFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQY-----SSTGDHKQLIVV 268
F + Y L ++ T L + A D+D N + Y S+ G + I +
Sbjct: 565 TFQKDAYVGALRENEPSVTQLVR----LRATDEDSPPNNQITYSIVSASAFGSYFD-ISL 619
Query: 269 NKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQF 328
+ G ++ ++ L E + I L +D + +T+ F
Sbjct: 620 YEGYGVISVSRPLDYEQISNGLIYLTVMAMDAGNPPLNSTVPVTIEVFDENDNPPT---F 676
Query: 329 TQKQYSTTVSEGASPGSVLLTL--TTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEV 385
++ Y +V E G+ +L L T + ++ E+ + + + + + +F IN +GE+
Sbjct: 677 SKPAYFVSVVENIMAGATVLFLNATDLDRSREYGQESIIYSLEGST---QFRINARSGEI 733
Query: 386 ILRRSLDYETTSNYFYQVMVTD-----SISNDTASINISVEDVNEWEPRFRHPQY 435
LD ET S Y V D + A++NI++ D+N+ P ++ Y
Sbjct: 734 TTTSLLDRETKSEYILIVRAVDGGVGHNQKTGIATVNITLLDINDNHPTWKDAPY 788
Score = 44.8 bits (101), Expect = 0.001
Identities = 36/111 (32%), Positives = 50/111 (45%), Gaps = 7/111 (6%)
Query: 328 FTQKQYST--TVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGE 384
FT + T +SE GS + L + + PL F VS FA+ + G
Sbjct: 31 FTNHFFDTYLLISEDTPVGSSVTQLLAQDMDND----PLVFGVSGEEASRFFAVEPDTGV 86
Query: 385 VILRRSLDYETTSNYFYQVMVTDSISNDTASINISVEDVNEWEPRFRHPQY 435
V LR+ LD ET S + + V+D T +NI V DVN+ P F + Y
Sbjct: 87 VWLRQPLDRETKSEFTVEFSVSDHQGVITRKVNIQVGDVNDNAPTFHNQPY 137
>AL359183-2|CAI13425.2| 1066|Homo sapiens cadherin-like 23 protein.
Length = 1066
Score = 92.3 bits (219), Expect = 7e-18
Identities = 102/442 (23%), Positives = 174/442 (39%), Gaps = 30/442 (6%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEKIG 70
ISEDTP+GS + L D D + +E + P + + L + LDRE K
Sbjct: 42 ISEDTPVGSSVTQLLAQ-DMDNDPLVFGVSGEEASRFFAVEPDTGVVWLRQPLDRETK-- 98
Query: 71 PSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXX 130
S V + V+++V DVNDNAP + PY+VR+ E
Sbjct: 99 -SEFTVEFSVSDHQGV---ITRKVNIQVGDVNDNAPTFHNQPYSVRIPEVGATGNTPVGT 154
Query: 131 XXSDRDQPGPHSALHYAVLPG--PHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQ 188
+ P +VL P S++ ++ I+ V + LD+ET + + +
Sbjct: 155 PIFIVNATDPDLGAGGSVLYSFQPPSQFFAIDS-ARGIVTVIRELDYETTQAYQLTVNAT 213
Query: 189 DQG-SPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQD 247
DQ + PL + L + + D D +P F Y+ + + + GT + I+A DQD
Sbjct: 214 DQDKTRPLSTLANLAIIITDVQDMDPIFINLPYSTNIYEHSPPGTTVRI----ITAIDQD 269
Query: 248 LGINAPLQY---SSTGDHKQLIVVNKDTGQVAATKQLIAE---LDPSVTIVLKATQVDNP 301
G + Y S G+ + ++ +G + L E + +K T++ N
Sbjct: 270 KGRPRGIGYTIVSVAGNTNSIFALDYISGVLTLNGLLDRENPLYSHGFILTVKGTEL-ND 328
Query: 302 DRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRE 361
DR +F +YS ++E A G L V E
Sbjct: 329 DRTPSDATVTTTFNILVIDINDNAPEFNSSEYSVAITELAQVGFALPLFIQVVDKDEGLN 388
Query: 362 SPLQFYV----SDRSFLDKFAINNAGEVILRRS--LDYETTSNYFYQVMVTDSISNDT-- 413
S + Y+ S + ++ ++ +R + LDYET Y + + +S+ +
Sbjct: 389 SMFEVYLVGNNSHHFIISPTSVQGKADIRIRVAIPLDYETVDRYDFDLFANESVPDHVGY 448
Query: 414 ASINISVEDVNEWEPRFRHPQY 435
A + I++ + N+ P F P Y
Sbjct: 449 AKVKITLINENDNRPIFSQPLY 470
Score = 80.6 bits (190), Expect = 2e-14
Identities = 106/480 (22%), Positives = 181/480 (37%), Gaps = 35/480 (7%)
Query: 57 LTLLRALDREEKIGPSNVYVNVRC----DRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAP 112
LTL LDRE + + V+ D R +D + ++ V D+NDNAP++ +
Sbjct: 300 LTLNGLLDRENPLYSHGFILTVKGTELNDDRTPSDATVTTTFNILVIDINDNAPEFNSSE 359
Query: 113 YAVRVSETXXXXXXX-XXXXXSDRDQPGPHSALHYAVLPGPHSEYL-----GFENELEPI 166
Y+V ++E D+D+ G +S L G +S + + + +
Sbjct: 360 YSVAITELAQVGFALPLFIQVVDKDE-GLNSMFE-VYLVGNNSHHFIISPTSVQGKADIR 417
Query: 167 IVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPD 226
I V PLD+ETV+ + L ++ P +++T+++ +D P F+ Y L +
Sbjct: 418 IRVAIPLDYETVDRYDFDL-FANESVPDHVGYAKVKITLINENDNRPIFSQPLYNISLYE 476
Query: 227 DAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLIAELD 286
+ GT + T + A D D G + Y + D + + +KDTG + +L EL
Sbjct: 477 NVTVGTSVLT----VLATDNDAGTFGEVSYFFSDDPDRFSL-DKDTGLIMLIARLDYELI 531
Query: 287 PSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSV 346
T+ + A + + F + Y + E +
Sbjct: 532 QRFTLTIIARDGGGEETTGRVRINVLDVNDNVPT-------FQKDAYVGALRENEPSVTQ 584
Query: 347 LLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAIN---NAGEVILRRSLDYETTSN--YFY 401
L+ L +++ VS +F F I+ G + + R LDYE SN +
Sbjct: 585 LVRLRATDEDSPPNNQITYSIVSASAFGSYFDISLYEGYGVISVSRPLDYEQISNGLIYL 644
Query: 402 QVMVTDSIS---NDTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXX 458
VM D+ + N T + I V D N+ P F P Y
Sbjct: 645 TVMAMDAGNPPLNSTVPVTIEVFDENDNPPTFSKPAYFVSVVENIMAGATVLFLNATDLD 704
Query: 459 VAHDGDAGTLALSLAGQHARMFYINASGDLFLREEAIGNLNSSSLHLVATAIDSGIPPRQ 518
+ + ++ SL G + F INA + S L+ A+D G+ Q
Sbjct: 705 RSREYGQESIIYSLEG--STQFRINARSGEITTTSLLDRETKSEYILIVRAVDGGVGHNQ 762
Score = 66.5 bits (155), Expect = 4e-10
Identities = 83/392 (21%), Positives = 146/392 (37%), Gaps = 17/392 (4%)
Query: 48 VGIVPGSKNLTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQ 107
+ + G +++ R LD E+ I +Y+ V + +PV++ V+D NDN P
Sbjct: 617 ISLYEGYGVISVSRPLDYEQ-ISNGLIYLTVMAMDAGNPPLNSTVPVTIEVFDENDNPPT 675
Query: 108 WEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPII 167
+ Y V V E +D D+ + +++ N I
Sbjct: 676 FSKPAYFVSVVENIMAGATVLFLNATDLDRSREYG--QESIIYSLEGSTQFRINARSGEI 733
Query: 168 VVKKPLDFETVNNFTIKLRVQD--QGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLP 225
LD ET + + + +R D G T+ +T+LD +D +P + Y L
Sbjct: 734 TTTSLLDRETKSEYILIVRAVDGGVGHNQKTGIATVNITLLDINDNHPTWKDAPYYINLV 793
Query: 226 DDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLI--A 283
+ + +TT + A D DLG N L YS +K +N TG++ T ++
Sbjct: 794 EMTPPDSDVTT----VVAVDPDLGENGTLVYSIQPPNK-FYSLNSTTGKIRTTHAMLDRE 848
Query: 284 ELDPSVTIVLKATQVDNPD--RYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGA 341
DP +++ V D R L F + V EG
Sbjct: 849 NPDPHEAELMRKIVVSVTDCGRPPLKATSSATVFVNLLDLNDNDPTFQNLPFVAEVLEGI 908
Query: 342 SPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFY 401
G + + + + +D +++G V+ LD E + Y
Sbjct: 909 PAGVSIYQVVAIDLDEGLNGLVSYRMPVGMPRMDFLINSSSGVVVTTTELDRERIAEYQL 968
Query: 402 QVMVTDS---ISNDTASINISVEDVNEWEPRF 430
+V+ +D+ + T+++ I V DVN+ P F
Sbjct: 969 RVVASDAGTPTKSSTSTLTIHVLDVNDETPTF 1000
Score = 66.5 bits (155), Expect = 4e-10
Identities = 45/168 (26%), Positives = 75/168 (44%), Gaps = 8/168 (4%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPG-P 152
V V + D+NDN P ++ P+ V E D D+ G + + Y + G P
Sbjct: 881 VFVNLLDLNDNDPTFQNLPFVAEVLEGIPAGVSIYQVVAIDLDE-GLNGLVSYRMPVGMP 939
Query: 153 HSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQN 212
++L N ++V LD E + + +++ D G+P S +TL + VLD +D+
Sbjct: 940 RMDFL--INSSSGVVVTTTELDRERIAEYQLRVVASDAGTPTKSSTSTLTIHVLDVNDET 997
Query: 213 PKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTG 260
P F Y + +D + ++ D D+G+NA L Y TG
Sbjct: 998 PTFFPAVYNVSVSEDVPREFRVVW----LNCTDNDVGLNAELSYFITG 1041
Score = 64.1 bits (149), Expect = 2e-09
Identities = 53/222 (23%), Positives = 94/222 (42%), Gaps = 10/222 (4%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVL-PGP 152
V + V DVNDN P ++ Y + E +D D P P++ + Y+++
Sbjct: 552 VRINVLDVNDNVPTFQKDAYVGALRENEPSVTQLVRLRATDEDSP-PNNQITYSIVSASA 610
Query: 153 HSEYLGFE-NELEPIIVVKKPLDFETVNNFTIKLRV--QDQGSPPLYSDTTLQVTVLDAD 209
Y E +I V +PLD+E ++N I L V D G+PPL S + + V D +
Sbjct: 611 FGSYFDISLYEGYGVISVSRPLDYEQISNGLIYLTVMAMDAGNPPLNSTVPVTIEVFDEN 670
Query: 210 DQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVN 269
D P F+ Y + ++ G + ++ G + YS G + +N
Sbjct: 671 DNPPTFSKPAYFVSVVENIMAGATVLFLNATDLDRSREYG-QESIIYSLEGSTQ--FRIN 727
Query: 270 KDTGQVAATKQLIAELDPSVTIVLKATQ--VDNPDRYALATL 309
+G++ T L E ++++A V + + +AT+
Sbjct: 728 ARSGEITTTSLLDRETKSEYILIVRAVDGGVGHNQKTGIATV 769
Score = 56.0 bits (129), Expect = 6e-07
Identities = 74/355 (20%), Positives = 144/355 (40%), Gaps = 30/355 (8%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
V + + + NDN P + Y + + E +D D G + Y P
Sbjct: 451 VKITLINENDNRPIFSQPLYNISLYENVTVGTSVLTVLATDNDA-GTFGEVSYFFSDDP- 508
Query: 154 SEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNP 213
+ + + I+++ + LD+E + FT+ + +D G + +++ VLD +D P
Sbjct: 509 -DRFSLDKDTGLIMLIAR-LDYELIQRFTLTIIARDGGGEE--TTGRVRINVLDVNDNVP 564
Query: 214 KFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQY-----SSTGDHKQLIVV 268
F + Y L ++ T L + A D+D N + Y S+ G + I +
Sbjct: 565 TFQKDAYVGALRENEPSVTQLVR----LRATDEDSPPNNQITYSIVSASAFGSYFD-ISL 619
Query: 269 NKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQF 328
+ G ++ ++ L E + I L +D + +T+ F
Sbjct: 620 YEGYGVISVSRPLDYEQISNGLIYLTVMAMDAGNPPLNSTVPVTIEVFDENDNPPT---F 676
Query: 329 TQKQYSTTVSEGASPGSVLLTL--TTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEV 385
++ Y +V E G+ +L L T + ++ E+ + + + + + +F IN +GE+
Sbjct: 677 SKPAYFVSVVENIMAGATVLFLNATDLDRSREYGQESIIYSLEGST---QFRINARSGEI 733
Query: 386 ILRRSLDYETTSNYFYQVMVTD-----SISNDTASINISVEDVNEWEPRFRHPQY 435
LD ET S Y V D + A++NI++ D+N+ P ++ Y
Sbjct: 734 TTTSLLDRETKSEYILIVRAVDGGVGHNQKTGIATVNITLLDINDNHPTWKDAPY 788
Score = 44.8 bits (101), Expect = 0.001
Identities = 36/111 (32%), Positives = 50/111 (45%), Gaps = 7/111 (6%)
Query: 328 FTQKQYST--TVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGE 384
FT + T +SE GS + L + + PL F VS FA+ + G
Sbjct: 31 FTNHFFDTYLLISEDTPVGSSVTQLLAQDMDND----PLVFGVSGEEASRFFAVEPDTGV 86
Query: 385 VILRRSLDYETTSNYFYQVMVTDSISNDTASINISVEDVNEWEPRFRHPQY 435
V LR+ LD ET S + + V+D T +NI V DVN+ P F + Y
Sbjct: 87 VWLRQPLDRETKSEFTVEFSVSDHQGVITRKVNIQVGDVNDNAPTFHNQPY 137
>AF217747-1|AAK51615.1| 797|Homo sapiens protocadherin-beta11
protein.
Length = 797
Score = 92.3 bits (219), Expect = 7e-18
Identities = 100/448 (22%), Positives = 190/448 (42%), Gaps = 33/448 (7%)
Query: 3 GGAVESFFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRL--QEKGAAVGIVPGSKNLTL 59
G SF ++E+ GS +G L+ + G +L R+ +K + + + +L L
Sbjct: 27 GSETWSFSVAEEMQSGSFVGNLAKDLGLKVRELSSRGARVVSNDKKQRLQLDINTGDLLL 86
Query: 60 LRALDREEKIG---PSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVR 116
LDREE G P +++ V +P+ + + ++V D+ND++P + +
Sbjct: 87 SETLDREELCGSIEPCVLHLQVLMQ-----NPTQFLQIELQVRDINDHSPIFSEKQMLLE 141
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEY---LGFENELEPIIVVKKPL 173
+ E D D G ++ Y + P H + +N P +V+ K L
Sbjct: 142 IPENSPVGAVFLLESAKDLDV-GINAVKSYTISPNSHFHIKMRVIPDNRKYPELVLDKAL 200
Query: 174 DFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTF 233
D+E + + L D GSPP ++V V+D +D +P+F Y + +++ G+
Sbjct: 201 DYEELPELSFILSALDGGSPPRSGTALVRVVVVDINDNSPEFEQAFYEVKIRENSILGSL 260
Query: 234 LTTSPGPISAADQDLGINAPLQYS---STGDHKQLIVVNKDTGQVAATKQLIAELDPSVT 290
+ +SA D D G N + Y+ ++ D ++ +N+ +G++ L E S +
Sbjct: 261 ILI----VSAWDLDSGTNGEICYTFSHASEDIRKTFEINQKSGEITLRAPLDFETIESYS 316
Query: 291 IVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTL 350
I+++AT D + +T+ + T ++ + E +P +V++
Sbjct: 317 IIIQAT--DGGGLFGKSTVIIHVIDVNDNAP-----EITVSSITSPIPEN-TPETVVMVF 368
Query: 351 TTVPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTD-SI 409
+ ++ + D F+ K ++ N + R LD E+T+ Y + VTD I
Sbjct: 369 SIQDIDSGDNGRIVCSIPEDLPFVLKSSVENYYTLETERPLDRESTAEYNITITVTDLGI 428
Query: 410 SNDTASIN--ISVEDVNEWEPRFRHPQY 435
N + V DVN+ P F Y
Sbjct: 429 PRLKTEHNTTVLVSDVNDNAPTFTQTSY 456
Score = 86.6 bits (205), Expect = 3e-16
Identities = 108/441 (24%), Positives = 168/441 (38%), Gaps = 27/441 (6%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
V V V D+NDN+P++E A Y V++ E D D G + + Y
Sbjct: 228 VRVVVVDINDNSPEFEQAFYEVKIRENSILGSLILIVSAWDLDS-GTNGEICYTFSHASE 286
Query: 154 SEYLGFE-NELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQN 212
FE N+ I ++ PLDFET+ +++I ++ D G L+ +T+ + V+D +D
Sbjct: 287 DIRKTFEINQKSGEITLRAPLDFETIESYSIIIQATDGGG--LFGKSTVIIHVIDVNDNA 344
Query: 213 PKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDT 272
P+ T T+ +P++ E + S D D G N + S D ++ + +
Sbjct: 345 PEITVSSITSPIPENTPETVVMV-----FSIQDIDSGDNGRIVCSIPEDLPFVLKSSVEN 399
Query: 273 GQVAATKQ-LIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQK 331
T++ L E I + T + P L T FTQ
Sbjct: 400 YYTLETERPLDRESTAEYNITITVTDLGIP---RLKTEHNTTVLVSDVNDNAPT--FTQT 454
Query: 332 QYSTTVSEGASP----GSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVI 386
Y+ V E SP GSV T N + S L +IN + G +
Sbjct: 455 SYTLFVRENNSPALHIGSVSATDRDSGTNAQVNYSLLPPQDLHLPLASLVSINTDNGHLF 514
Query: 387 LRRSLDYETTSNYFYQVMVTDSIS---NDTASINISVEDVNEWEPRFRHPQYEFEXXXXX 443
RSLDYE + ++V TD S + A + + V D N+ P +P
Sbjct: 515 ALRSLDYEALQAFDFRVGATDRGSPALSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTE 574
Query: 444 XXXXXXXXXXXXXXXVAHDGDAGTLA-LS---LAGQHARMFYINASGDLFLREEAIGNLN 499
VA DGD+G A LS L +F + A + +
Sbjct: 575 LVPRAAEPGYLVTKVVAVDGDSGQNAWLSYQLLKATEPGLFGVWAHNGEVRTARLLSERD 634
Query: 500 SSSLHLVATAIDSGIPPRQTS 520
++ LV D+G PPR +
Sbjct: 635 AAKHRLVVLVKDNGEPPRSAT 655
Score = 76.6 bits (180), Expect = 4e-13
Identities = 90/316 (28%), Positives = 136/316 (43%), Gaps = 30/316 (9%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAV--GIVPGSKNLTLLRALDREEK 68
I E+TP +++ S+ S D G I + E V V L R LDRE
Sbjct: 356 IPENTP-ETVVMVFSIQDIDSGDNGRIVCSIPEDLPFVLKSSVENYYTLETERPLDREST 414
Query: 69 IGPSNVYVNVRC--DRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXX 126
N+ + V R T+ + + VS DVNDNAP + Y + V E
Sbjct: 415 -AEYNITITVTDLGIPRLKTEHNTTVLVS----DVNDNAPTFTQTSYTLFVRENNSPALH 469
Query: 127 XXXXXXSDRDQPGPHSALHYAVLPG-----PHSEYLGFENELEPIIVVKKPLDFETVNNF 181
+DRD G ++ ++Y++LP P + + + + ++ LD+E + F
Sbjct: 470 IGSVSATDRDS-GTNAQVNYSLLPPQDLHLPLASLVSINTDNGHLFALRS-LDYEALQAF 527
Query: 182 TIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTY------EHYTALLPDDAEEGTFLT 235
++ D+GSP L S+ ++V VLDA+D +P Y T L+P AE G +T
Sbjct: 528 DFRVGATDRGSPALSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVT 587
Query: 236 TSPGPISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPSV-TIVL 293
+ A D D G NA L Y L V G+V T +L++E D + +V+
Sbjct: 588 ----KVVAVDGDSGQNAWLSYQLLKATEPGLFGVWAHNGEV-RTARLLSERDAAKHRLVV 642
Query: 294 KATQVDNPDRYALATL 309
P R A ATL
Sbjct: 643 LVKDNGEPPRSATATL 658
>AF152490-1|AAD43751.1| 797|Homo sapiens protocadherin beta 11
protein.
Length = 797
Score = 92.3 bits (219), Expect = 7e-18
Identities = 100/448 (22%), Positives = 190/448 (42%), Gaps = 33/448 (7%)
Query: 3 GGAVESFFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRL--QEKGAAVGIVPGSKNLTL 59
G SF ++E+ GS +G L+ + G +L R+ +K + + + +L L
Sbjct: 27 GSETWSFSVAEEMQSGSFVGNLAKDLGLKVRELSSRGARVVSNDKKQRLQLDINTGDLLL 86
Query: 60 LRALDREEKIG---PSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVR 116
LDREE G P +++ V +P+ + + ++V D+ND++P + +
Sbjct: 87 SETLDREELCGSIEPCVLHLQVLMQ-----NPTQFLQIELQVRDINDHSPIFSEKQMLLE 141
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEY---LGFENELEPIIVVKKPL 173
+ E D D G ++ Y + P H + +N P +V+ K L
Sbjct: 142 IPENSPVGAVFLLESAKDLDV-GINAVKSYTISPNSHFHIKMRVIPDNRKYPELVLDKAL 200
Query: 174 DFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTF 233
D+E + + L D GSPP ++V V+D +D +P+F Y + +++ G+
Sbjct: 201 DYEELPELSFILSALDGGSPPRSGTALVRVVVVDINDNSPEFEQAFYEVKIRENSILGSL 260
Query: 234 LTTSPGPISAADQDLGINAPLQYS---STGDHKQLIVVNKDTGQVAATKQLIAELDPSVT 290
+ +SA D D G N + Y+ ++ D ++ +N+ +G++ L E S +
Sbjct: 261 ILI----VSAWDLDSGTNGEICYTFSHASEDIRKTFEINQKSGEITLRAPLDFETIESYS 316
Query: 291 IVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTL 350
I+++AT D + +T+ + T ++ + E +P +V++
Sbjct: 317 IIIQAT--DGGGLFGKSTVIIHVIDVNDNAP-----EITVSSITSPIPEN-TPETVVMVF 368
Query: 351 TTVPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTD-SI 409
+ ++ + D F+ K ++ N + R LD E+T+ Y + VTD I
Sbjct: 369 SIQDIDSGDNGRIVCSIPEDLPFVLKSSVENYYTLETERPLDRESTAEYNITITVTDLGI 428
Query: 410 SNDTASIN--ISVEDVNEWEPRFRHPQY 435
N + V DVN+ P F Y
Sbjct: 429 PRLKTEHNTTVLVSDVNDNAPTFTQTSY 456
Score = 86.6 bits (205), Expect = 3e-16
Identities = 108/441 (24%), Positives = 168/441 (38%), Gaps = 27/441 (6%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
V V V D+NDN+P++E A Y V++ E D D G + + Y
Sbjct: 228 VRVVVVDINDNSPEFEQAFYEVKIRENSILGSLILIVSAWDLDS-GTNGEICYTFSHASE 286
Query: 154 SEYLGFE-NELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQN 212
FE N+ I ++ PLDFET+ +++I ++ D G L+ +T+ + V+D +D
Sbjct: 287 DIRKTFEINQKSGEITLRAPLDFETIESYSIIIQATDGGG--LFGKSTVIIHVIDVNDNA 344
Query: 213 PKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDT 272
P+ T T+ +P++ E + S D D G N + S D ++ + +
Sbjct: 345 PEITVSSITSPIPENTPETVVMV-----FSIQDIDSGDNGRIVCSIPEDLPFVLKSSVEN 399
Query: 273 GQVAATKQ-LIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQK 331
T++ L E I + T + P L T FTQ
Sbjct: 400 YYTLETERPLDRESTAEYNITITVTDLGIP---RLKTEHNTTVLVSDVNDNAPT--FTQT 454
Query: 332 QYSTTVSEGASP----GSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVI 386
Y+ V E SP GSV T N + S L +IN + G +
Sbjct: 455 SYTLFVRENNSPALHIGSVSATDRDSGTNAQVNYSLLPPQDLHLPLASLVSINTDNGHLF 514
Query: 387 LRRSLDYETTSNYFYQVMVTDSIS---NDTASINISVEDVNEWEPRFRHPQYEFEXXXXX 443
RSLDYE + ++V TD S + A + + V D N+ P +P
Sbjct: 515 ALRSLDYEALQAFDFRVGATDRGSPALSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTE 574
Query: 444 XXXXXXXXXXXXXXXVAHDGDAGTLA-LS---LAGQHARMFYINASGDLFLREEAIGNLN 499
VA DGD+G A LS L +F + A + +
Sbjct: 575 LVPRAAEPGYLVTKVVAVDGDSGQNAWLSYQLLKATEPGLFGVWAHNGEVRTARLLSERD 634
Query: 500 SSSLHLVATAIDSGIPPRQTS 520
++ LV D+G PPR +
Sbjct: 635 AAKHRLVVLVKDNGEPPRSAT 655
Score = 76.6 bits (180), Expect = 4e-13
Identities = 90/316 (28%), Positives = 136/316 (43%), Gaps = 30/316 (9%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAV--GIVPGSKNLTLLRALDREEK 68
I E+TP +++ S+ S D G I + E V V L R LDRE
Sbjct: 356 IPENTP-ETVVMVFSIQDIDSGDNGRIVCSIPEDLPFVLKSSVENYYTLETERPLDREST 414
Query: 69 IGPSNVYVNVRC--DRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXX 126
N+ + V R T+ + + VS DVNDNAP + Y + V E
Sbjct: 415 -AEYNITITVTDLGIPRLKTEHNTTVLVS----DVNDNAPTFTQTSYTLFVRENNSPALH 469
Query: 127 XXXXXXSDRDQPGPHSALHYAVLPG-----PHSEYLGFENELEPIIVVKKPLDFETVNNF 181
+DRD G ++ ++Y++LP P + + + + ++ LD+E + F
Sbjct: 470 IGSVSATDRDS-GTNAQVNYSLLPPQDLHLPLASLVSINTDNGHLFALRS-LDYEALQAF 527
Query: 182 TIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTY------EHYTALLPDDAEEGTFLT 235
++ D+GSP L S+ ++V VLDA+D +P Y T L+P AE G +T
Sbjct: 528 DFRVGATDRGSPALSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVT 587
Query: 236 TSPGPISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPSV-TIVL 293
+ A D D G NA L Y L V G+V T +L++E D + +V+
Sbjct: 588 ----KVVAVDGDSGQNAWLSYQLLKATEPGLFGVWAHNGEV-RTARLLSERDAAKHRLVV 642
Query: 294 KATQVDNPDRYALATL 309
P R A ATL
Sbjct: 643 LVKDNGEPPRSATATL 658
>AB208958-1|BAD92195.1| 895|Homo sapiens protocadherin gamma
subfamily A, 7 isoform 1 precursor variant protein.
Length = 895
Score = 92.3 bits (219), Expect = 7e-18
Identities = 100/436 (22%), Positives = 176/436 (40%), Gaps = 30/436 (6%)
Query: 14 DTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRA--LDREEKIG 70
+T GS +G ++ + G +L + +R+ +G ++ +L+ A +DREE
Sbjct: 1 ETDKGSFVGDIAKDLGLEPRELAERGVRIISRGRTQLFALNQRSGSLVTAGRIDREEICA 60
Query: 71 PS-NVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXX 129
S VN D + P+ V + D+NDN P++ V++ E
Sbjct: 61 QSARCLVNFNI---LMEDKMNLYPIDVEIIDINDNVPRFLTEEINVKIMENTAPGVRFPL 117
Query: 130 XXXSDRDQPGPHSALHYAVLPGPHSEYL---GFENELEPIIVVKKPLDFETVNNFTIKLR 186
D D G +S Y + P H G + P +V+++ LD E +
Sbjct: 118 SEAGDPDV-GTNSLQSYQLSPNRHFSLAVQSGDDGTKYPELVLERVLDREEERVHHLVFT 176
Query: 187 VQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQ 246
D G PP S +QVTV+D +D P F+ Y +P++ GT L T + A D
Sbjct: 177 ASDGGDPPRSSTAHIQVTVVDVNDHTPVFSLPQYQVTVPENVPVGTRLLT----VHAIDL 232
Query: 247 DLGINAPLQYS---STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDR 303
D G+N + YS T ++ +N TG+++ + L + + + ++ D P
Sbjct: 233 DEGVNGEVTYSFRKITPKLPKMFHLNSLTGEISTLEGL--DYEETAFYEMEVQAQDGP-- 288
Query: 304 YALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESP 363
+L + T S+++ E G+V+ +++
Sbjct: 289 ---GSLTKAKVLITVLDVNDNAPEVTMTSLSSSIPEDTPLGTVIALFYLQDRDSGKNGEV 345
Query: 364 LQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDS----ISNDTASINIS 419
+ F + +I+N ++ ++LD ET S Y + TD +S +T I +
Sbjct: 346 TCTIPENLPFKLEKSIDNYYRLVTTKNLDRETLSLYNITLKATDGGTPPLSRET-HIFMQ 404
Query: 420 VEDVNEWEPRFRHPQY 435
V D N+ P F H Y
Sbjct: 405 VADTNDNPPTFPHSSY 420
Score = 76.2 bits (179), Expect = 5e-13
Identities = 75/313 (23%), Positives = 122/313 (38%), Gaps = 22/313 (7%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEK--GAAVGIVPGSKNLTLLRALDREEK 68
I EDTP+G++I + S G++T + E + L + LDRE
Sbjct: 319 IPEDTPLGTVIALFYLQDRDSGKNGEVTCTIPENLPFKLEKSIDNYYRLVTTKNLDRETL 378
Query: 69 IGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXX 128
S + ++ T S + ++V D NDN P + + Y+V ++E
Sbjct: 379 ---SLYNITLKATDGGTPPLSRETHIFMQVADTNDNPPTFPHSSYSVYIAENNPRGASIF 435
Query: 129 XXXXSDRDQPG----PHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIK 184
D D +S + P S Y+ ++ ++ + D+E + ++
Sbjct: 436 LVTAQDHDSEDNAQITYSLAEDTIQGAPVSSYVSINSDTG-VLYALQSFDYEQLRELQLR 494
Query: 185 LRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFL---TTSPG-- 239
+ D G PPL S+ +L + VLD +D P+ Y LP D G L + PG
Sbjct: 495 VTAHDSGDPPLSSNMSLSLFVLDQNDNPPEILY----PALPTDGSTGMELAPRSAEPGYL 550
Query: 240 --PISAADQDLGINAPLQY-SSTGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKAT 296
+ A D+D G NA L Y L V TG+V + L+ ++V+
Sbjct: 551 VTKVVAVDKDSGQNAWLSYLLLKASEPGLFAVGLYTGEVRTARALLDRDALKQSLVVAVQ 610
Query: 297 QVDNPDRYALATL 309
P A TL
Sbjct: 611 DHGQPPLSATVTL 623
Score = 63.7 bits (148), Expect = 3e-09
Identities = 55/217 (25%), Positives = 93/217 (42%), Gaps = 18/217 (8%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
V + V DVNDNAP+ + + E DRD G + + + P
Sbjct: 296 VLITVLDVNDNAPEVTMTSLSSSIPEDTPLGTVIALFYLQDRDS-GKNGEVTCTI---PE 351
Query: 154 SEYLGFENELEPI--IVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQ 211
+ E ++ +V K LD ET++ + I L+ D G+PPL +T + + V D +D
Sbjct: 352 NLPFKLEKSIDNYYRLVTTKNLDRETLSLYNITLKATDGGTPPLSRETHIFMQVADTNDN 411
Query: 212 NPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQ------L 265
P F + Y+ + ++ G + ++A D D NA + YS D Q
Sbjct: 412 PPTFPHSSYSVYIAENNPRGASIFL----VTAQDHDSEDNAQITYSLAEDTIQGAPVSSY 467
Query: 266 IVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPD 302
+ +N DTG + A + + + + L+ T D+ D
Sbjct: 468 VSINSDTGVLYALQSF--DYEQLRELQLRVTAHDSGD 502
Score = 37.9 bits (84), Expect = 0.16
Identities = 50/212 (23%), Positives = 83/212 (39%), Gaps = 13/212 (6%)
Query: 8 SFFISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQE---KGAAVG-IVPGSKNLTLLRAL 63
S +I+E+ P G+ I ++ SED IT L E +GA V V + + +L AL
Sbjct: 421 SVYIAENNPRGASIFLVTAQDHDSEDNAQITYSLAEDTIQGAPVSSYVSINSDTGVLYAL 480
Query: 64 DREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQ-------WEGAPYAVR 116
+ + + V S + +S+ V D NDN P+ +G+
Sbjct: 481 QSFDYEQLRELQLRVTAHDSGDPPLSSNMSLSLFVLDQNDNPPEILYPALPTDGSTGMEL 540
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFE 176
+ D+D G ++ L Y +L + + LD +
Sbjct: 541 APRSAEPGYLVTKVVAVDKDS-GQNAWLSYLLLKASEPGLFAVGLYTGEVRTARALLDRD 599
Query: 177 TVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDA 208
+ ++ + VQD G PPL + TL V V D+
Sbjct: 600 ALKQ-SLVVAVQDHGQPPLSATVTLTVAVADS 630
>D31784-1|BAA06562.1| 790|Homo sapiens cadherin-6 protein.
Length = 790
Score = 91.5 bits (217), Expect = 1e-17
Identities = 105/424 (24%), Positives = 183/424 (43%), Gaps = 41/424 (9%)
Query: 32 EDLGDITLRLQEKGAAVG----IVPGSKNLTLLRALDREEKIGPSNVYV-NVRCDRRRTT 86
+D GD +L+ G G I + ++ + LDREEK VY+ + RRT
Sbjct: 81 QDRGDGSLKYILSGDGAGDLFIINENTGDIQATKRLDREEK----PVYILRAQAINRRTG 136
Query: 87 DPSFVIPVS---VRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQP--GPH 141
P V P S +++ D+NDN P + Y V E +D D P G
Sbjct: 137 RP--VEPESEFIIKIHDINDNEPIFTKEVYTATVPEMSDVGTFVVQVTATDADDPTYGNS 194
Query: 142 SALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSP--PLYSDT 199
+ + Y++L G Y E+E I +D E + + ++ +D G L T
Sbjct: 195 AKVVYSILQG--QPYFSVESETGIIKTALLNMDRENREQYQVVIQAKDMGGQMGGLSGTT 252
Query: 200 TLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSST 259
T+ +T+ D +D P+F Y P+ + GT + G I A+D D+G NA ++YS T
Sbjct: 253 TVNITLTDVNDNPPRFPQSTYQFKTPESSPPGTPI----GRIKASDADVGENAEIEYSIT 308
Query: 260 -GDHKQL--IVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNP---DRYA-LATLXXX 312
G+ + ++ +++T + T + + + + LK + NP R+ L
Sbjct: 309 DGEGLDMFDVITDQETQEGIITVKKLLDFEKKKVYTLK-VEASNPYVEPRFLYLGPFKDS 367
Query: 313 XXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRS 372
F++ Y + E A + + ++T Q+ + +P+++ V +
Sbjct: 368 ATVRIVVEDVDEPPVFSKLAYILQIREDAQINTTIGSVTA--QDPDAARNPVKYSVDRHT 425
Query: 373 FLDK-FAINNA-GEVILRRSLDYETTSNYFYQVMVTDSISNDTAS----INISVEDVNEW 426
+D+ F I++ G + + LD ET + V+ T+ I+N S + I V DVN+
Sbjct: 426 DMDRIFNIDSGNGSIFTSKLLDRETLLWHNITVIATE-INNPKQSSRVPLYIKVLDVNDN 484
Query: 427 EPRF 430
P F
Sbjct: 485 APEF 488
Score = 50.4 bits (115), Expect = 3e-05
Identities = 47/203 (23%), Positives = 89/203 (43%), Gaps = 13/203 (6%)
Query: 244 ADQDLGINAPLQYSSTGDHK-QLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPD 302
+DQD G + L+Y +GD L ++N++TG + ATK+L E P +L+A ++
Sbjct: 79 SDQDRG-DGSLKYILSGDGAGDLFIINENTGDIQATKRLDREEKP--VYILRAQAINR-- 133
Query: 303 RYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRES 362
R FT++ Y+ TV E + G+ ++ +T + +
Sbjct: 134 RTGRPVEPESEFIIKIHDINDNEPIFTKEVYTATVPEMSDVGTFVVQVTATDADDPTYGN 193
Query: 363 PLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSIS-------NDTAS 415
+ S F++ + +I L+ + + YQV++ + T +
Sbjct: 194 SAKVVYSILQGQPYFSVESETGIIKTALLNMDRENREQYQVVIQAKDMGGQMGGLSGTTT 253
Query: 416 INISVEDVNEWEPRFRHPQYEFE 438
+NI++ DVN+ PRF Y+F+
Sbjct: 254 VNITLTDVNDNPPRFPQSTYQFK 276
Score = 47.6 bits (108), Expect = 2e-04
Identities = 66/307 (21%), Positives = 121/307 (39%), Gaps = 24/307 (7%)
Query: 136 DQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLR-VQDQGSPP 194
DQ +L Y +L G + L NE I K LD E + ++ + + + P
Sbjct: 80 DQDRGDGSLKY-ILSGDGAGDLFIINENTGDIQATKRLDREEKPVYILRAQAINRRTGRP 138
Query: 195 LYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPL 254
+ ++ + + D +D P FT E YTA +P+ ++ GTF+ A D G +A +
Sbjct: 139 VEPESEFIIKIHDINDNEPIFTKEVYTATVPEMSDVGTFVVQVTA-TDADDPTYGNSAKV 197
Query: 255 QYSSTGDHKQLIVVNKDTGQV-AATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXX 313
YS + V +TG + A + E +V++A + T
Sbjct: 198 VYSIL-QGQPYFSVESETGIIKTALLNMDRENREQYQVVIQAKDMGGQMGGLSGT---TT 253
Query: 314 XXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSF 373
+F Q Y E + PG+ + + + + +++ ++D
Sbjct: 254 VNITLTDVNDNPPRFPQSTYQFKTPESSPPGTPIGRIKASDADVG-ENAEIEYSITDGEG 312
Query: 374 LDKFAI-----NNAGEVILRRSLDYETTSNYFYQVMVTDSI----------SNDTASINI 418
LD F + G + +++ LD+E Y +V ++ D+A++ I
Sbjct: 313 LDMFDVITDQETQEGIITVKKLLDFEKKKVYTLKVEASNPYVEPRFLYLGPFKDSATVRI 372
Query: 419 SVEDVNE 425
VEDV+E
Sbjct: 373 VVEDVDE 379
Score = 36.7 bits (81), Expect = 0.37
Identities = 43/206 (20%), Positives = 78/206 (37%), Gaps = 12/206 (5%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITL---RLQEKGAAVGIVPGSKNLTLLRALDREE 67
I ED I + IG+++ DP + R + I G+ ++ + LDRE
Sbjct: 392 IREDAQINTTIGSVTAQ-DPDAARNPVKYSVDRHTDMDRIFNIDSGNGSIFTSKLLDRET 450
Query: 68 KIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXX 127
+ + + V S +P+ ++V DVNDNAP++ Y V E
Sbjct: 451 LLWHN---ITVIATEINNPKQSSRVPLYIKVLDVNDNAPEF-AEFYETFVCEKAKADQLI 506
Query: 128 XXXXXSDRDQPGPHSALHYAVLP----GPHSEYLGFENELEPIIVVKKPLDFETVNNFTI 183
D+D P +++ P G + ++ I+ K + ++ + +
Sbjct: 507 QTLHAVDKDDPYSGHQFSFSLAPEAASGSNFTIQDNKDNTAGILTRKNGYNRHEMSTYLL 566
Query: 184 KLRVQDQGSPPLYSDTTLQVTVLDAD 209
+ + D P S T+ V V D
Sbjct: 567 PVVISDNDYPVQSSTGTVTVRVCACD 592
>BC000019-1|AAH00019.1| 663|Homo sapiens CDH6 protein protein.
Length = 663
Score = 91.5 bits (217), Expect = 1e-17
Identities = 105/424 (24%), Positives = 183/424 (43%), Gaps = 41/424 (9%)
Query: 32 EDLGDITLRLQEKGAAVG----IVPGSKNLTLLRALDREEKIGPSNVYV-NVRCDRRRTT 86
+D GD +L+ G G I + ++ + LDREEK VY+ + RRT
Sbjct: 81 QDRGDGSLKYILSGDGAGDLFIINENTGDIQATKRLDREEK----PVYILRAQAINRRTG 136
Query: 87 DPSFVIPVS---VRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQP--GPH 141
P V P S +++ D+NDN P + Y V E +D D P G
Sbjct: 137 RP--VEPESEFIIKIHDINDNEPIFTKEVYTATVPEMSDVGTFVVQVTATDADDPTYGNS 194
Query: 142 SALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSP--PLYSDT 199
+ + Y++L G Y E+E I +D E + + ++ +D G L T
Sbjct: 195 AKVVYSILQG--QPYFSVESETGIIKTALLNMDRENREQYQVVIQAKDMGGQMGGLSGTT 252
Query: 200 TLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSST 259
T+ +T+ D +D P+F Y P+ + GT + G I A+D D+G NA ++YS T
Sbjct: 253 TVNITLTDVNDNPPRFPQSTYQFKTPESSPPGTPI----GRIKASDADVGENAEIEYSIT 308
Query: 260 -GDHKQL--IVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNP---DRYA-LATLXXX 312
G+ + ++ +++T + T + + + + LK + NP R+ L
Sbjct: 309 DGEGLDMFDVITDQETQEGIITVKKLLDFEKKKVYTLK-VEASNPYVEPRFLYLGPFKDS 367
Query: 313 XXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRS 372
F++ Y + E A + + ++T Q+ + +P+++ V +
Sbjct: 368 ATVRIVVEDVDEPPVFSKLAYILQIREDAQINTTIGSVTA--QDPDAARNPVKYSVDRHT 425
Query: 373 FLDK-FAINNA-GEVILRRSLDYETTSNYFYQVMVTDSISNDTAS----INISVEDVNEW 426
+D+ F I++ G + + LD ET + V+ T+ I+N S + I V DVN+
Sbjct: 426 DMDRIFNIDSGNGSIFTSKLLDRETLLWHNITVIATE-INNPKQSSRVPLYIKVLDVNDN 484
Query: 427 EPRF 430
P F
Sbjct: 485 APEF 488
Score = 50.4 bits (115), Expect = 3e-05
Identities = 47/203 (23%), Positives = 89/203 (43%), Gaps = 13/203 (6%)
Query: 244 ADQDLGINAPLQYSSTGDHK-QLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPD 302
+DQD G + L+Y +GD L ++N++TG + ATK+L E P +L+A ++
Sbjct: 79 SDQDRG-DGSLKYILSGDGAGDLFIINENTGDIQATKRLDREEKP--VYILRAQAINR-- 133
Query: 303 RYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRES 362
R FT++ Y+ TV E + G+ ++ +T + +
Sbjct: 134 RTGRPVEPESEFIIKIHDINDNEPIFTKEVYTATVPEMSDVGTFVVQVTATDADDPTYGN 193
Query: 363 PLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSIS-------NDTAS 415
+ S F++ + +I L+ + + YQV++ + T +
Sbjct: 194 SAKVVYSILQGQPYFSVESETGIIKTALLNMDRENREQYQVVIQAKDMGGQMGGLSGTTT 253
Query: 416 INISVEDVNEWEPRFRHPQYEFE 438
+NI++ DVN+ PRF Y+F+
Sbjct: 254 VNITLTDVNDNPPRFPQSTYQFK 276
Score = 47.6 bits (108), Expect = 2e-04
Identities = 66/307 (21%), Positives = 121/307 (39%), Gaps = 24/307 (7%)
Query: 136 DQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLR-VQDQGSPP 194
DQ +L Y +L G + L NE I K LD E + ++ + + + P
Sbjct: 80 DQDRGDGSLKY-ILSGDGAGDLFIINENTGDIQATKRLDREEKPVYILRAQAINRRTGRP 138
Query: 195 LYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPL 254
+ ++ + + D +D P FT E YTA +P+ ++ GTF+ A D G +A +
Sbjct: 139 VEPESEFIIKIHDINDNEPIFTKEVYTATVPEMSDVGTFVVQVTA-TDADDPTYGNSAKV 197
Query: 255 QYSSTGDHKQLIVVNKDTGQV-AATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXX 313
YS + V +TG + A + E +V++A + T
Sbjct: 198 VYSIL-QGQPYFSVESETGIIKTALLNMDRENREQYQVVIQAKDMGGQMGGLSGT---TT 253
Query: 314 XXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSF 373
+F Q Y E + PG+ + + + + +++ ++D
Sbjct: 254 VNITLTDVNDNPPRFPQSTYQFKTPESSPPGTPIGRIKASDADVG-ENAEIEYSITDGEG 312
Query: 374 LDKFAI-----NNAGEVILRRSLDYETTSNYFYQVMVTDSI----------SNDTASINI 418
LD F + G + +++ LD+E Y +V ++ D+A++ I
Sbjct: 313 LDMFDVITDQETQEGIITVKKLLDFEKKKVYTLKVEASNPYVEPRFLYLGPFKDSATVRI 372
Query: 419 SVEDVNE 425
VEDV+E
Sbjct: 373 VVEDVDE 379
Score = 36.7 bits (81), Expect = 0.37
Identities = 43/206 (20%), Positives = 78/206 (37%), Gaps = 12/206 (5%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITL---RLQEKGAAVGIVPGSKNLTLLRALDREE 67
I ED I + IG+++ DP + R + I G+ ++ + LDRE
Sbjct: 392 IREDAQINTTIGSVTAQ-DPDAARNPVKYSVDRHTDMDRIFNIDSGNGSIFTSKLLDRET 450
Query: 68 KIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXX 127
+ + + V S +P+ ++V DVNDNAP++ Y V E
Sbjct: 451 LLWHN---ITVIATEINNPKQSSRVPLYIKVLDVNDNAPEF-AEFYETFVCEKAKADQLI 506
Query: 128 XXXXXSDRDQPGPHSALHYAVLP----GPHSEYLGFENELEPIIVVKKPLDFETVNNFTI 183
D+D P +++ P G + ++ I+ K + ++ + +
Sbjct: 507 QTLHAVDKDDPYSGHQFSFSLAPEAASGSNFTIQDNKDNTAGILTRKNGYNRHEMSTYLL 566
Query: 184 KLRVQDQGSPPLYSDTTLQVTVLDAD 209
+ + D P S T+ V V D
Sbjct: 567 PVVISDNDYPVQSSTGTVTVRVCACD 592
>AF152485-1|AAD43746.1| 789|Homo sapiens protocadherin alpha 7
short form protein protein.
Length = 789
Score = 91.5 bits (217), Expect = 1e-17
Identities = 97/382 (25%), Positives = 154/382 (40%), Gaps = 20/382 (5%)
Query: 63 LDREEKIGPS---NVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSE 119
+DREE G S ++++ V +R P V V V V D+NDN P + + ++E
Sbjct: 90 IDREELCGRSAECSIHLEVIVER-----PLQVFHVDVEVKDINDNPPVFPATQRNLFIAE 144
Query: 120 TXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH--SEYLGFENELEPI-IVVKKPLDFE 176
+ SD D G ++ L Y + P + + +++P+ +V++K LD E
Sbjct: 145 SRPLDSRFPLEGASDAD-IGENALLTYRLSPNEYFFLDVPTSNQQVKPLGLVLRKLLDRE 203
Query: 177 TVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTT 236
+ L D G P L L +TVLD +D P F YT LP++ GT L
Sbjct: 204 ETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVKLPENVSIGT-LVI 262
Query: 237 SPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKAT 296
P +A+D D G+N + YS + D I ++ +I +D + K
Sbjct: 263 HP---NASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMDFEESRAHK-I 318
Query: 297 QVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQN 356
V+ D+ Q T S + E A PG+V+ ++ ++
Sbjct: 319 PVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVITLISVFDRD 378
Query: 357 TEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSISND---T 413
F N ++L +LD E+ S Y V D S T
Sbjct: 379 FGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPSLWAT 438
Query: 414 ASINISVEDVNEWEPRFRHPQY 435
AS+++ V DVN+ P F P+Y
Sbjct: 439 ASVSVEVADVNDNAPAFAQPEY 460
Score = 88.6 bits (210), Expect = 9e-17
Identities = 106/449 (23%), Positives = 184/449 (40%), Gaps = 40/449 (8%)
Query: 8 SFFISEDTPIGSIIGTLSVNGDPSEDLGD---ITLRLQEKGAAVGIVPGSKN------LT 58
+ FI+E P+ S + G D+G+ +T RL VP S L
Sbjct: 139 NLFIAESRPLDS---RFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVKPLGLV 195
Query: 59 LLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVS 118
L + LDREE +++ + + + + + + V D NDNAP ++ Y V++
Sbjct: 196 LRKLLDREET---PELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVKLP 252
Query: 119 ETXXXXXXXXXXXXSDRDQPGPHSALHYA----VLPGPHSEYLGFENELEPIIVVKKPLD 174
E SD D+ G + + Y+ V P S++ + L I V +D
Sbjct: 253 ENVSIGTLVIHPNASDLDE-GLNGDIIYSFSSDVSPDIKSKF--HMDPLSGAITVIGHMD 309
Query: 175 FETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFL 234
FE I + D+G PPL T+ V V+D +D P+ T + +P+DA+ GT +
Sbjct: 310 FEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVI 369
Query: 235 TTSPGPISAADQDLGINAPLQYSSTGDHK-QLIVVNKDTGQVAATKQLIAELDPSVTIVL 293
T IS D+D G+N + S T +L+ K+ + L E + +V+
Sbjct: 370 TL----ISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVV 425
Query: 294 KATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTT- 352
A +P +A A++ F Q +Y+ V E PG + T++
Sbjct: 426 TARDGGSPSLWATASVSVEVADVNDNAPA-----FAQPEYTVFVKENNPPGCHIFTVSAG 480
Query: 353 ---VPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTDS 408
+N S ++ V +R+ +++ +G+V + LD+E +QV D+
Sbjct: 481 DADAQKNALVSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540
Query: 409 ---ISNDTASINISVEDVNEWEPRFRHPQ 434
++ + V D N+ P P+
Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPR 569
>AF152481-1|AAD43742.1| 824|Homo sapiens protocadherin alpha 3
short form protein protein.
Length = 824
Score = 91.5 bits (217), Expect = 1e-17
Identities = 115/449 (25%), Positives = 188/449 (41%), Gaps = 43/449 (9%)
Query: 9 FFISEDTPIGSIIGTLSVNGDPSEDLGDITLRL-----QEKGAAVGIVPGSKNLTLLRAL 63
+ +SE+ G+ +G ++ D +L ++ RL + G + + + L + +
Sbjct: 33 YSVSEEAKHGTFVGRIAQ--DLGLELAELVPRLFRVASKRHGDLLEVNLQNGILFVNSRI 90
Query: 64 DREEKIGPS---NVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSET 120
DREE G S ++++ V DR P V V V V D+NDNAP + A + +SE+
Sbjct: 91 DREELCGRSAECSIHLEVIVDR-----PLQVFHVEVEVKDINDNAPVFPMAVKNLFISES 145
Query: 121 XXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFE-----NELEPI-IVVKKPLD 174
SD D G +S L Y++ +EY + E++ + +V+KK L+
Sbjct: 146 RQPGSRFSLEGASDADI-GTNSLLTYSL---DSTEYFTLDVKRNDEEIKSLGLVLKKNLN 201
Query: 175 FETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFL 234
E + + D G P L T L++TVLD +D P F Y L ++A GT +
Sbjct: 202 REDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAPAFERTIYKVRLLENAPNGTLV 261
Query: 235 TTSPGPISAADQDLGINAPLQYSSTGDHKQLIV----VNKDTGQVAATKQLIAELDPSVT 290
T ++A D D G+N + YS D I+ ++ GQ++ + E S
Sbjct: 262 VT----VNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNGQISVKGNIDFEESKSYE 317
Query: 291 IVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTL 350
I ++AT NP T+ + + S V E SP S ++ L
Sbjct: 318 IQVEATDKGNPPMSDHCTVLLEIVDINDNVP-----ELVIQSLSLPVLED-SPLSTVIAL 371
Query: 351 TTVPQNTEFRESPLQFYVSDR-SFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSI 409
+V + ++ F N ++L LD E+ S Y V D
Sbjct: 372 ISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSAYELVVTARDGG 431
Query: 410 SND---TASINISVEDVNEWEPRFRHPQY 435
S TAS+++ V DVN+ P F +Y
Sbjct: 432 SPSLWATASVSVEVADVNDNAPAFSQSEY 460
Score = 83.4 bits (197), Expect = 3e-15
Identities = 80/353 (22%), Positives = 154/353 (43%), Gaps = 23/353 (6%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
+ + V DVNDNAP +E Y VR+ E +D D+ G + + Y+
Sbjct: 228 LKITVLDVNDNAPAFERTIYKVRLLENAPNGTLVVTVNATDLDE-GVNKDIAYSFNTDMS 286
Query: 154 SEYLGFENELEPI---IVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADD 210
++ L + L+P+ I VK +DFE ++ I++ D+G+PP+ T+ + ++D +D
Sbjct: 287 ADILS-KFHLDPVNGQISVKGNIDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDIND 345
Query: 211 QNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHK-QLIVVN 269
P+ + + + +D+ L+T IS +D+D G+N + S T +L+
Sbjct: 346 NVPELVIQSLSLPVLEDSP----LSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTF 401
Query: 270 KDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFT 329
K+ + L E + +V+ A +P +A A++ F+
Sbjct: 402 KNYYSLVLDSPLDRESVSAYELVVTARDGGSPSLWATASVSVEVADVNDNAPA-----FS 456
Query: 330 QKQYSTTVSEGASPGSVLLTLTT----VPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGE 384
Q +Y+ V E PG + T++ +N S ++ V +R+ +++ +G+
Sbjct: 457 QSEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSLVERRVGERALSSYVSVHAESGK 516
Query: 385 VILRRSLDYETTSNYFYQVMVTDS---ISNDTASINISVEDVNEWEPRFRHPQ 434
V + LD+E +QV D+ ++ + V D N+ P P+
Sbjct: 517 VYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLMPR 569
Score = 71.3 bits (167), Expect = 1e-11
Identities = 87/318 (27%), Positives = 125/318 (39%), Gaps = 30/318 (9%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKN---LTLLRALDREE 67
+ ED+P+ ++I +SV+ S G +T L +V KN L L LDRE
Sbjct: 359 VLEDSPLSTVIALISVSDRDSGVNGQVTCSLTPH-VPFKLVSTFKNYYSLVLDSPLDRES 417
Query: 68 KIGPSNVYVNVRCDRRRTTDPSF--VIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXX 125
+ + V R PS VSV V DVNDNAP + + Y V V E
Sbjct: 418 -VSAYELVVTARDGG----SPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGC 472
Query: 126 XXXXXXXSDRDQPG----PHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNF 181
D D +S + V S Y+ E + ++ PLD E +
Sbjct: 473 HIFTVSARDADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQ-PLDHEELELL 531
Query: 182 TIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEH-------YTALLPDDAEEGTFL 234
++ +D G PPL S+ TLQV VLD +D P + L+P G +
Sbjct: 532 QFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVV 591
Query: 235 TTSPGPISAADQDLGINAPLQYS---STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTI 291
+ A D D G NA L Y TG + V TG+++ T+ L P +
Sbjct: 592 ----AKVRAVDADSGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRL 647
Query: 292 VLKATQVDNPDRYALATL 309
++ P A AT+
Sbjct: 648 LVLVKDHGEPSLTATATV 665
>AF152315-1|AAD43709.1| 937|Homo sapiens protocadherin alpha 7
protein.
Length = 937
Score = 91.5 bits (217), Expect = 1e-17
Identities = 97/382 (25%), Positives = 154/382 (40%), Gaps = 20/382 (5%)
Query: 63 LDREEKIGPS---NVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSE 119
+DREE G S ++++ V +R P V V V V D+NDN P + + ++E
Sbjct: 90 IDREELCGRSAECSIHLEVIVER-----PLQVFHVDVEVKDINDNPPVFPATQRNLFIAE 144
Query: 120 TXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH--SEYLGFENELEPI-IVVKKPLDFE 176
+ SD D G ++ L Y + P + + +++P+ +V++K LD E
Sbjct: 145 SRPLDSRFPLEGASDAD-IGENALLTYRLSPNEYFFLDVPTSNQQVKPLGLVLRKLLDRE 203
Query: 177 TVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTT 236
+ L D G P L L +TVLD +D P F YT LP++ GT L
Sbjct: 204 ETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVKLPENVSIGT-LVI 262
Query: 237 SPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKAT 296
P +A+D D G+N + YS + D I ++ +I +D + K
Sbjct: 263 HP---NASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMDFEESRAHK-I 318
Query: 297 QVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQN 356
V+ D+ Q T S + E A PG+V+ ++ ++
Sbjct: 319 PVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVITLISVFDRD 378
Query: 357 TEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSISND---T 413
F N ++L +LD E+ S Y V D S T
Sbjct: 379 FGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPSLWAT 438
Query: 414 ASINISVEDVNEWEPRFRHPQY 435
AS+++ V DVN+ P F P+Y
Sbjct: 439 ASVSVEVADVNDNAPAFAQPEY 460
Score = 88.6 bits (210), Expect = 9e-17
Identities = 106/449 (23%), Positives = 184/449 (40%), Gaps = 40/449 (8%)
Query: 8 SFFISEDTPIGSIIGTLSVNGDPSEDLGD---ITLRLQEKGAAVGIVPGSKN------LT 58
+ FI+E P+ S + G D+G+ +T RL VP S L
Sbjct: 139 NLFIAESRPLDS---RFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVKPLGLV 195
Query: 59 LLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVS 118
L + LDREE +++ + + + + + + V D NDNAP ++ Y V++
Sbjct: 196 LRKLLDREET---PELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVKLP 252
Query: 119 ETXXXXXXXXXXXXSDRDQPGPHSALHYA----VLPGPHSEYLGFENELEPIIVVKKPLD 174
E SD D+ G + + Y+ V P S++ + L I V +D
Sbjct: 253 ENVSIGTLVIHPNASDLDE-GLNGDIIYSFSSDVSPDIKSKF--HMDPLSGAITVIGHMD 309
Query: 175 FETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFL 234
FE I + D+G PPL T+ V V+D +D P+ T + +P+DA+ GT +
Sbjct: 310 FEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVI 369
Query: 235 TTSPGPISAADQDLGINAPLQYSSTGDHK-QLIVVNKDTGQVAATKQLIAELDPSVTIVL 293
T IS D+D G+N + S T +L+ K+ + L E + +V+
Sbjct: 370 TL----ISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVV 425
Query: 294 KATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTT- 352
A +P +A A++ F Q +Y+ V E PG + T++
Sbjct: 426 TARDGGSPSLWATASVSVEVADVNDNAPA-----FAQPEYTVFVKENNPPGCHIFTVSAG 480
Query: 353 ---VPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTDS 408
+N S ++ V +R+ +++ +G+V + LD+E +QV D+
Sbjct: 481 DADAQKNALVSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540
Query: 409 ---ISNDTASINISVEDVNEWEPRFRHPQ 434
++ + V D N+ P P+
Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPR 569
>AF152311-1|AAD43705.1| 950|Homo sapiens protocadherin alpha 3
protein.
Length = 950
Score = 91.5 bits (217), Expect = 1e-17
Identities = 115/449 (25%), Positives = 188/449 (41%), Gaps = 43/449 (9%)
Query: 9 FFISEDTPIGSIIGTLSVNGDPSEDLGDITLRL-----QEKGAAVGIVPGSKNLTLLRAL 63
+ +SE+ G+ +G ++ D +L ++ RL + G + + + L + +
Sbjct: 33 YSVSEEAKHGTFVGRIAQ--DLGLELAELVPRLFRVASKRHGDLLEVNLQNGILFVNSRI 90
Query: 64 DREEKIGPS---NVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSET 120
DREE G S ++++ V DR P V V V V D+NDNAP + A + +SE+
Sbjct: 91 DREELCGRSAECSIHLEVIVDR-----PLQVFHVEVEVKDINDNAPVFPMAVKNLFISES 145
Query: 121 XXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFE-----NELEPI-IVVKKPLD 174
SD D G +S L Y++ +EY + E++ + +V+KK L+
Sbjct: 146 RQPGSRFSLEGASDADI-GTNSLLTYSL---DSTEYFTLDVKRNDEEIKSLGLVLKKNLN 201
Query: 175 FETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFL 234
E + + D G P L T L++TVLD +D P F Y L ++A GT +
Sbjct: 202 REDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAPAFERTIYKVRLLENAPNGTLV 261
Query: 235 TTSPGPISAADQDLGINAPLQYSSTGDHKQLIV----VNKDTGQVAATKQLIAELDPSVT 290
T ++A D D G+N + YS D I+ ++ GQ++ + E S
Sbjct: 262 VT----VNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNGQISVKGNIDFEESKSYE 317
Query: 291 IVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTL 350
I ++AT NP T+ + + S V E SP S ++ L
Sbjct: 318 IQVEATDKGNPPMSDHCTVLLEIVDINDNVP-----ELVIQSLSLPVLED-SPLSTVIAL 371
Query: 351 TTVPQNTEFRESPLQFYVSDR-SFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSI 409
+V + ++ F N ++L LD E+ S Y V D
Sbjct: 372 ISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSAYELVVTARDGG 431
Query: 410 SND---TASINISVEDVNEWEPRFRHPQY 435
S TAS+++ V DVN+ P F +Y
Sbjct: 432 SPSLWATASVSVEVADVNDNAPAFSQSEY 460
Score = 83.4 bits (197), Expect = 3e-15
Identities = 80/353 (22%), Positives = 154/353 (43%), Gaps = 23/353 (6%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
+ + V DVNDNAP +E Y VR+ E +D D+ G + + Y+
Sbjct: 228 LKITVLDVNDNAPAFERTIYKVRLLENAPNGTLVVTVNATDLDE-GVNKDIAYSFNTDMS 286
Query: 154 SEYLGFENELEPI---IVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADD 210
++ L + L+P+ I VK +DFE ++ I++ D+G+PP+ T+ + ++D +D
Sbjct: 287 ADILS-KFHLDPVNGQISVKGNIDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDIND 345
Query: 211 QNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHK-QLIVVN 269
P+ + + + +D+ L+T IS +D+D G+N + S T +L+
Sbjct: 346 NVPELVIQSLSLPVLEDSP----LSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTF 401
Query: 270 KDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFT 329
K+ + L E + +V+ A +P +A A++ F+
Sbjct: 402 KNYYSLVLDSPLDRESVSAYELVVTARDGGSPSLWATASVSVEVADVNDNAPA-----FS 456
Query: 330 QKQYSTTVSEGASPGSVLLTLTT----VPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGE 384
Q +Y+ V E PG + T++ +N S ++ V +R+ +++ +G+
Sbjct: 457 QSEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSLVERRVGERALSSYVSVHAESGK 516
Query: 385 VILRRSLDYETTSNYFYQVMVTDS---ISNDTASINISVEDVNEWEPRFRHPQ 434
V + LD+E +QV D+ ++ + V D N+ P P+
Sbjct: 517 VYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLMPR 569
Score = 71.3 bits (167), Expect = 1e-11
Identities = 87/318 (27%), Positives = 125/318 (39%), Gaps = 30/318 (9%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKN---LTLLRALDREE 67
+ ED+P+ ++I +SV+ S G +T L +V KN L L LDRE
Sbjct: 359 VLEDSPLSTVIALISVSDRDSGVNGQVTCSLTPH-VPFKLVSTFKNYYSLVLDSPLDRES 417
Query: 68 KIGPSNVYVNVRCDRRRTTDPSF--VIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXX 125
+ + V R PS VSV V DVNDNAP + + Y V V E
Sbjct: 418 -VSAYELVVTARDGG----SPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGC 472
Query: 126 XXXXXXXSDRDQPG----PHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNF 181
D D +S + V S Y+ E + ++ PLD E +
Sbjct: 473 HIFTVSARDADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQ-PLDHEELELL 531
Query: 182 TIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEH-------YTALLPDDAEEGTFL 234
++ +D G PPL S+ TLQV VLD +D P + L+P G +
Sbjct: 532 QFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVV 591
Query: 235 TTSPGPISAADQDLGINAPLQYS---STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTI 291
+ A D D G NA L Y TG + V TG+++ T+ L P +
Sbjct: 592 ----AKVRAVDADSGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRL 647
Query: 292 VLKATQVDNPDRYALATL 309
++ P A AT+
Sbjct: 648 LVLVKDHGEPSLTATATV 665
>AC005609-11|AAC34323.1| 824|Homo sapiens KIAA0345-like 11 protein.
Length = 824
Score = 91.5 bits (217), Expect = 1e-17
Identities = 115/449 (25%), Positives = 188/449 (41%), Gaps = 43/449 (9%)
Query: 9 FFISEDTPIGSIIGTLSVNGDPSEDLGDITLRL-----QEKGAAVGIVPGSKNLTLLRAL 63
+ +SE+ G+ +G ++ D +L ++ RL + G + + + L + +
Sbjct: 33 YSVSEEAKHGTFVGRIAQ--DLGLELAELVPRLFRVASKRHGDLLEVNLQNGILFVNSRI 90
Query: 64 DREEKIGPS---NVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSET 120
DREE G S ++++ V DR P V V V V D+NDNAP + A + +SE+
Sbjct: 91 DREELCGRSAECSIHLEVIVDR-----PLQVFHVEVEVKDINDNAPVFPMAVKNLFISES 145
Query: 121 XXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFE-----NELEPI-IVVKKPLD 174
SD D G +S L Y++ +EY + E++ + +V+KK L+
Sbjct: 146 RQPGSRFSLEGASDADI-GTNSLLTYSL---DSTEYFTLDVKRNDEEIKSLGLVLKKNLN 201
Query: 175 FETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFL 234
E + + D G P L T L++TVLD +D P F Y L ++A GT +
Sbjct: 202 REDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAPAFERTIYKVRLLENAPNGTLV 261
Query: 235 TTSPGPISAADQDLGINAPLQYSSTGDHKQLIV----VNKDTGQVAATKQLIAELDPSVT 290
T ++A D D G+N + YS D I+ ++ GQ++ + E S
Sbjct: 262 VT----VNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNGQISVKGNIDFEESKSYE 317
Query: 291 IVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTL 350
I ++AT NP T+ + + S V E SP S ++ L
Sbjct: 318 IQVEATDKGNPPMSDHCTVLLEIVDINDNVP-----ELVIQSLSLPVLED-SPLSTVIAL 371
Query: 351 TTVPQNTEFRESPLQFYVSDR-SFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSI 409
+V + ++ F N ++L LD E+ S Y V D
Sbjct: 372 ISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSAYELVVTARDGG 431
Query: 410 SND---TASINISVEDVNEWEPRFRHPQY 435
S TAS+++ V DVN+ P F +Y
Sbjct: 432 SPSLWATASVSVEVADVNDNAPAFSQSEY 460
Score = 83.4 bits (197), Expect = 3e-15
Identities = 80/353 (22%), Positives = 154/353 (43%), Gaps = 23/353 (6%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
+ + V DVNDNAP +E Y VR+ E +D D+ G + + Y+
Sbjct: 228 LKITVLDVNDNAPAFERTIYKVRLLENAPNGTLVVTVNATDLDE-GVNKDIAYSFNTDMS 286
Query: 154 SEYLGFENELEPI---IVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADD 210
++ L + L+P+ I VK +DFE ++ I++ D+G+PP+ T+ + ++D +D
Sbjct: 287 ADILS-KFHLDPVNGQISVKGNIDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDIND 345
Query: 211 QNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHK-QLIVVN 269
P+ + + + +D+ L+T IS +D+D G+N + S T +L+
Sbjct: 346 NVPELVIQSLSLPVLEDSP----LSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTF 401
Query: 270 KDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFT 329
K+ + L E + +V+ A +P +A A++ F+
Sbjct: 402 KNYYSLVLDSPLDRESVSAYELVVTARDGGSPSLWATASVSVEVADVNDNAPA-----FS 456
Query: 330 QKQYSTTVSEGASPGSVLLTLTT----VPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGE 384
Q +Y+ V E PG + T++ +N S ++ V +R+ +++ +G+
Sbjct: 457 QSEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSLVERRVGERALSSYVSVHAESGK 516
Query: 385 VILRRSLDYETTSNYFYQVMVTDS---ISNDTASINISVEDVNEWEPRFRHPQ 434
V + LD+E +QV D+ ++ + V D N+ P P+
Sbjct: 517 VYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLMPR 569
Score = 71.3 bits (167), Expect = 1e-11
Identities = 87/318 (27%), Positives = 125/318 (39%), Gaps = 30/318 (9%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKN---LTLLRALDREE 67
+ ED+P+ ++I +SV+ S G +T L +V KN L L LDRE
Sbjct: 359 VLEDSPLSTVIALISVSDRDSGVNGQVTCSLTPH-VPFKLVSTFKNYYSLVLDSPLDRES 417
Query: 68 KIGPSNVYVNVRCDRRRTTDPSF--VIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXX 125
+ + V R PS VSV V DVNDNAP + + Y V V E
Sbjct: 418 -VSAYELVVTARDGG----SPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGC 472
Query: 126 XXXXXXXSDRDQPG----PHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNF 181
D D +S + V S Y+ E + ++ PLD E +
Sbjct: 473 HIFTVSARDADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQ-PLDHEELELL 531
Query: 182 TIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEH-------YTALLPDDAEEGTFL 234
++ +D G PPL S+ TLQV VLD +D P + L+P G +
Sbjct: 532 QFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVV 591
Query: 235 TTSPGPISAADQDLGINAPLQYS---STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTI 291
+ A D D G NA L Y TG + V TG+++ T+ L P +
Sbjct: 592 ----AKVRAVDADSGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRL 647
Query: 292 VLKATQVDNPDRYALATL 309
++ P A AT+
Sbjct: 648 LVLVKDHGEPSLTATATV 665
>AC005609-7|AAC34319.1| 789|Homo sapiens KIAA0345-like 7 protein.
Length = 789
Score = 91.5 bits (217), Expect = 1e-17
Identities = 97/382 (25%), Positives = 154/382 (40%), Gaps = 20/382 (5%)
Query: 63 LDREEKIGPS---NVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSE 119
+DREE G S ++++ V +R P V V V V D+NDN P + + ++E
Sbjct: 90 IDREELCGRSAECSIHLEVIVER-----PLQVFHVDVEVKDINDNPPVFPATQRNLFIAE 144
Query: 120 TXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH--SEYLGFENELEPI-IVVKKPLDFE 176
+ SD D G ++ L Y + P + + +++P+ +V++K LD E
Sbjct: 145 SRPLDSRFPLEGASDAD-IGENALLTYRLSPNEYFFLDVPTSNQQVKPLGLVLRKLLDRE 203
Query: 177 TVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTT 236
+ L D G P L L +TVLD +D P F YT LP++ GT L
Sbjct: 204 ETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVKLPENVSIGT-LVI 262
Query: 237 SPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKAT 296
P +A+D D G+N + YS + D I ++ +I +D + K
Sbjct: 263 HP---NASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMDFEESRAHK-I 318
Query: 297 QVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQN 356
V+ D+ Q T S + E A PG+V+ ++ ++
Sbjct: 319 PVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVITLISVFDRD 378
Query: 357 TEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSISND---T 413
F N ++L +LD E+ S Y V D S T
Sbjct: 379 FGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPSLWAT 438
Query: 414 ASINISVEDVNEWEPRFRHPQY 435
AS+++ V DVN+ P F P+Y
Sbjct: 439 ASVSVEVADVNDNAPAFAQPEY 460
Score = 88.6 bits (210), Expect = 9e-17
Identities = 106/449 (23%), Positives = 184/449 (40%), Gaps = 40/449 (8%)
Query: 8 SFFISEDTPIGSIIGTLSVNGDPSEDLGD---ITLRLQEKGAAVGIVPGSKN------LT 58
+ FI+E P+ S + G D+G+ +T RL VP S L
Sbjct: 139 NLFIAESRPLDS---RFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVKPLGLV 195
Query: 59 LLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVS 118
L + LDREE +++ + + + + + + V D NDNAP ++ Y V++
Sbjct: 196 LRKLLDREET---PELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVKLP 252
Query: 119 ETXXXXXXXXXXXXSDRDQPGPHSALHYA----VLPGPHSEYLGFENELEPIIVVKKPLD 174
E SD D+ G + + Y+ V P S++ + L I V +D
Sbjct: 253 ENVSIGTLVIHPNASDLDE-GLNGDIIYSFSSDVSPDIKSKF--HMDPLSGAITVIGHMD 309
Query: 175 FETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFL 234
FE I + D+G PPL T+ V V+D +D P+ T + +P+DA+ GT +
Sbjct: 310 FEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVI 369
Query: 235 TTSPGPISAADQDLGINAPLQYSSTGDHK-QLIVVNKDTGQVAATKQLIAELDPSVTIVL 293
T IS D+D G+N + S T +L+ K+ + L E + +V+
Sbjct: 370 TL----ISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVV 425
Query: 294 KATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTT- 352
A +P +A A++ F Q +Y+ V E PG + T++
Sbjct: 426 TARDGGSPSLWATASVSVEVADVNDNAPA-----FAQPEYTVFVKENNPPGCHIFTVSAG 480
Query: 353 ---VPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTDS 408
+N S ++ V +R+ +++ +G+V + LD+E +QV D+
Sbjct: 481 DADAQKNALVSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540
Query: 409 ---ISNDTASINISVEDVNEWEPRFRHPQ 434
++ + V D N+ P P+
Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPR 569
>BC113609-1|AAI13610.1| 798|Homo sapiens protocadherin alpha 4
protein.
Length = 798
Score = 91.1 bits (216), Expect = 2e-17
Identities = 110/446 (24%), Positives = 182/446 (40%), Gaps = 37/446 (8%)
Query: 9 FFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAAVGIVPGSKN--LTLLRALDR 65
+ +SE+ G+ +G ++ + G +L R+ KG + +N L + +DR
Sbjct: 33 YSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKGRGGLLEVNLQNGILFVNSRIDR 92
Query: 66 EE---KIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXX 122
EE + ++++ V DR P V V V V D+NDN P + + ++E+
Sbjct: 93 EELCRRSAECSIHLEVIVDR-----PLQVFHVDVEVRDINDNPPVFPATQKNLSIAESRP 147
Query: 123 XXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIV------VKKPLDFE 176
SD D G ++ L Y + P +EY E + +V ++K LD E
Sbjct: 148 LDSRFPLEGASDADI-GENALLTYRLSP---NEYFSLEKPPDDELVKGLGLILRKSLDRE 203
Query: 177 TVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTT 236
+ L D G P L L +TVLDA+D P F Y L ++ GT +
Sbjct: 204 EAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAFDRTIYKVRLLENVPNGTLVI- 262
Query: 237 SPGPISAADQDLGINAPLQYSSTGD----HKQLIVVNKDTGQVAATKQLIAELDPSVTIV 292
++A+D D G+N + YS + D K ++ TGQ+ + E S I+
Sbjct: 263 ---KLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQIIVKGYIDFEESKSYEII 319
Query: 293 LKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTT 352
++ +D + L+ L+F K S + E A G+V+ ++
Sbjct: 320 VEG--IDK-GQLPLSGHCRVIVEVEDNNDNVPDLEF--KSLSLPIREDAPLGTVIALISV 374
Query: 353 VPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSISND 412
++ S F N ++L +LD E+ S Y V D S
Sbjct: 375 SDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS 434
Query: 413 ---TASINISVEDVNEWEPRFRHPQY 435
TAS+++ V DVN+ P F P+Y
Sbjct: 435 LWATASVSVEVADVNDNAPAFAQPEY 460
Score = 78.6 bits (185), Expect = 9e-14
Identities = 91/390 (23%), Positives = 164/390 (42%), Gaps = 26/390 (6%)
Query: 57 LTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVR 116
L L ++LDREE P V D + + + + + + V D NDNAP ++ Y VR
Sbjct: 194 LILRKSLDREE--APEIFLVLTATDGGKP-ELTGTVQLLITVLDANDNAPAFDRTIYKVR 250
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPI---IVVKKPL 173
+ E SD D+ G + + Y+ S + + ++PI I+VK +
Sbjct: 251 LLENVPNGTLVIKLNASDLDE-GLNGDIVYS-FSNDISPNVKSKFHIDPITGQIIVKGYI 308
Query: 174 DFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTF 233
DFE ++ I + D+G PL + V V D +D P ++ + + +DA GT
Sbjct: 309 DFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIREDAPLGTV 368
Query: 234 LTTSPGPISAADQDLGINAPLQYSSTGDHK-QLIVVNKDTGQVAATKQLIAELDPSVTIV 292
+ IS +D+D+G+N + S T +L+ K+ + L E + +V
Sbjct: 369 IAL----ISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYELV 424
Query: 293 LKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTT 352
+ A +P +A A++ F Q +Y+ V E PG + T++
Sbjct: 425 VTARDGGSPSLWATASVSVEVADVNDNAPA-----FAQPEYTVFVKENNPPGCHIFTVSA 479
Query: 353 ----VPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTD 407
+N S ++ V +R+ +++ +G+V + LD+E +QV D
Sbjct: 480 WDADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARD 539
Query: 408 S---ISNDTASINISVEDVNEWEPRFRHPQ 434
+ ++ + V D N+ P P+
Sbjct: 540 AGVPPLGSNVTLQVFVLDENDNAPALLAPR 569
Score = 70.1 bits (164), Expect = 3e-11
Identities = 90/318 (28%), Positives = 125/318 (39%), Gaps = 30/318 (9%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKN---LTLLRALDREE 67
I ED P+G++I +SV+ G +T L +V KN L L ALDRE
Sbjct: 359 IREDAPLGTVIALISVSDKDMGVNGLVTCSLTSH-VPFKLVSTFKNYYSLVLDSALDRES 417
Query: 68 KIGPSNVYVNVRCDRRRTTDPSF--VIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXX 125
+ + V R PS VSV V DVNDNAP + Y V V E
Sbjct: 418 -VSAYELVVTARDGG----SPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGC 472
Query: 126 XXXXXXXSDRDQPG----PHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNF 181
D D +S + V S Y+ E + ++ PLD E +
Sbjct: 473 HIFTVSAWDADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQ-PLDHEELELL 531
Query: 182 TIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKF-------TYEHYTALLPDDAEEGTFL 234
++ +D G PPL S+ TLQV VLD +D P T + L+P G +
Sbjct: 532 QFQVTARDAGVPPLGSNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVV 591
Query: 235 TTSPGPISAADQDLGINAPLQYS---STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTI 291
+ A D D G NA L Y TG + V TG+++ T+ L P +
Sbjct: 592 ----AKVRAVDADSGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRL 647
Query: 292 VLKATQVDNPDRYALATL 309
++ P A AT+
Sbjct: 648 LVLVKDHGEPALTATATV 665
>BC112102-1|AAI12103.1| 798|Homo sapiens protocadherin alpha 4,
isoform 2 precursor protein.
Length = 798
Score = 91.1 bits (216), Expect = 2e-17
Identities = 110/446 (24%), Positives = 182/446 (40%), Gaps = 37/446 (8%)
Query: 9 FFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAAVGIVPGSKN--LTLLRALDR 65
+ +SE+ G+ +G ++ + G +L R+ KG + +N L + +DR
Sbjct: 33 YSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKGRGGLLEVNLQNGILFVNSRIDR 92
Query: 66 EE---KIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXX 122
EE + ++++ V DR P V V V V D+NDN P + + ++E+
Sbjct: 93 EELCRRSAECSIHLEVIVDR-----PLQVFHVDVEVRDINDNPPVFPATQKNLSIAESRP 147
Query: 123 XXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIV------VKKPLDFE 176
SD D G ++ L Y + P +EY E + +V ++K LD E
Sbjct: 148 LDSRFPLEGASDADI-GENALLTYRLSP---NEYFSLEKPPDDELVKGLGLILRKSLDRE 203
Query: 177 TVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTT 236
+ L D G P L L +TVLDA+D P F Y L ++ GT +
Sbjct: 204 EAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAFDRTIYKVRLLENVPNGTLVI- 262
Query: 237 SPGPISAADQDLGINAPLQYSSTGD----HKQLIVVNKDTGQVAATKQLIAELDPSVTIV 292
++A+D D G+N + YS + D K ++ TGQ+ + E S I+
Sbjct: 263 ---KLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQIIVKGYIDFEESKSYEII 319
Query: 293 LKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTT 352
++ +D + L+ L+F K S + E A G+V+ ++
Sbjct: 320 VEG--IDK-GQLPLSGHCRVIVEVEDNNDNVPDLEF--KSLSLPIREDAPLGTVIALISV 374
Query: 353 VPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSISND 412
++ S F N ++L +LD E+ S Y V D S
Sbjct: 375 SDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS 434
Query: 413 ---TASINISVEDVNEWEPRFRHPQY 435
TAS+++ V DVN+ P F P+Y
Sbjct: 435 LWATASVSVEVADVNDNAPAFAQPEY 460
Score = 78.6 bits (185), Expect = 9e-14
Identities = 91/390 (23%), Positives = 164/390 (42%), Gaps = 26/390 (6%)
Query: 57 LTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVR 116
L L ++LDREE P V D + + + + + + V D NDNAP ++ Y VR
Sbjct: 194 LILRKSLDREE--APEIFLVLTATDGGKP-ELTGTVQLLITVLDANDNAPAFDRTIYKVR 250
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPI---IVVKKPL 173
+ E SD D+ G + + Y+ S + + ++PI I+VK +
Sbjct: 251 LLENVPNGTLVIKLNASDLDE-GLNGDIVYS-FSNDISPNVKSKFHIDPITGQIIVKGYI 308
Query: 174 DFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTF 233
DFE ++ I + D+G PL + V V D +D P ++ + + +DA GT
Sbjct: 309 DFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIREDAPLGTV 368
Query: 234 LTTSPGPISAADQDLGINAPLQYSSTGDHK-QLIVVNKDTGQVAATKQLIAELDPSVTIV 292
+ IS +D+D+G+N + S T +L+ K+ + L E + +V
Sbjct: 369 IAL----ISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYELV 424
Query: 293 LKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTT 352
+ A +P +A A++ F Q +Y+ V E PG + T++
Sbjct: 425 VTARDGGSPSLWATASVSVEVADVNDNAPA-----FAQPEYTVFVKENNPPGCHIFTVSA 479
Query: 353 ----VPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTD 407
+N S ++ V +R+ +++ +G+V + LD+E +QV D
Sbjct: 480 WDADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARD 539
Query: 408 S---ISNDTASINISVEDVNEWEPRFRHPQ 434
+ ++ + V D N+ P P+
Sbjct: 540 AGVPPLGSNVTLQVFVLDENDNAPALLAPR 569
Score = 70.1 bits (164), Expect = 3e-11
Identities = 90/318 (28%), Positives = 125/318 (39%), Gaps = 30/318 (9%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKN---LTLLRALDREE 67
I ED P+G++I +SV+ G +T L +V KN L L ALDRE
Sbjct: 359 IREDAPLGTVIALISVSDKDMGVNGLVTCSLTSH-VPFKLVSTFKNYYSLVLDSALDRES 417
Query: 68 KIGPSNVYVNVRCDRRRTTDPSF--VIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXX 125
+ + V R PS VSV V DVNDNAP + Y V V E
Sbjct: 418 -VSAYELVVTARDGG----SPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGC 472
Query: 126 XXXXXXXSDRDQPG----PHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNF 181
D D +S + V S Y+ E + ++ PLD E +
Sbjct: 473 HIFTVSAWDADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQ-PLDHEELELL 531
Query: 182 TIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKF-------TYEHYTALLPDDAEEGTFL 234
++ +D G PPL S+ TLQV VLD +D P T + L+P G +
Sbjct: 532 QFQVTARDAGVPPLGSNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVV 591
Query: 235 TTSPGPISAADQDLGINAPLQYS---STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTI 291
+ A D D G NA L Y TG + V TG+++ T+ L P +
Sbjct: 592 ----AKVRAVDADSGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRL 647
Query: 292 VLKATQVDNPDRYALATL 309
++ P A AT+
Sbjct: 648 LVLVKDHGEPALTATATV 665
>BC093875-1|AAH93875.1| 850|Homo sapiens protocadherin gamma
subfamily A, 10 protein.
Length = 850
Score = 91.1 bits (216), Expect = 2e-17
Identities = 112/444 (25%), Positives = 184/444 (41%), Gaps = 34/444 (7%)
Query: 8 SFFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAA--VGIVPGSKNLTLLRALD 64
S+ I E+ GS +G +S + G +L + +R+ +G + P S +L +D
Sbjct: 36 SYSIPEELEKGSFVGNISKDLGLAPRELAERGVRIVSRGRTQLFSLNPRSGSLVTAGRID 95
Query: 65 REEKIGPSN---VYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETX 121
REE S V N+ + R + + + V D+NDNAP+++ V+++E
Sbjct: 96 REELCAQSARCVVSFNILVEDRVK-----LFGIEIEVTDINDNAPKFQAENLDVKINENV 150
Query: 122 XXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYL--GFENELE-PIIVVKKPLDFETV 178
D D G +S Y + P H N ++ P +V++ LD E
Sbjct: 151 AAGMRFPLPEAIDPDV-GVNSLQSYQLSPNKHFSLRVQSRANGVKYPELVLEHSLDREEE 209
Query: 179 NNFTIKLRVQDQGSPPLYSDTTL-QVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTS 237
+ L D G PL S T L VTV DA+D P FT Y +P++ GT L T
Sbjct: 210 AIHHLVLTASD-GGDPLRSGTVLVSVTVFDANDNAPVFTLPEYRVSVPENLPVGTQLLT- 267
Query: 238 PGPISAADQDLGINAPLQYS--STGDHKQL-IVVNKDTGQVAATKQLIAELDPSVTIVLK 294
++A D+D G N + YS D + L +NK TG++ ++ L E I ++
Sbjct: 268 ---VTATDRDEGANGEVTYSFRKLPDTQLLKFQLNKYTGEIKISENLDYEETGFYEIEIQ 324
Query: 295 ATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVP 354
A A L + T + V+E + G+V+ L
Sbjct: 325 AED-------GGAYLATAKVLITVEDVNDNSPELTITSLFSPVTEDSPLGTVVALLNVHD 377
Query: 355 QNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSIS---N 411
++E ++ F + +I++ +++ R+LD E S+Y V TD S +
Sbjct: 378 LDSEQNGQVTCSILAYLPFKLEKSIDSYYRLVIHRALDREQVSSYNITVTATDGGSPPLS 437
Query: 412 DTASINISVEDVNEWEPRFRHPQY 435
A + V D+N+ P F Y
Sbjct: 438 TEAHFMLQVADINDNPPTFSQVSY 461
Score = 80.2 bits (189), Expect = 3e-14
Identities = 76/315 (24%), Positives = 128/315 (40%), Gaps = 26/315 (8%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQE--KGAAVGIVPGSKNLTLLRALDREEK 68
++ED+P+G+++ L+V+ SE G +T + + L + RALDRE+
Sbjct: 360 VTEDSPLGTVVALLNVHDLDSEQNGQVTCSILAYLPFKLEKSIDSYYRLVIHRALDREQ- 418
Query: 69 IGPSNVYVNVRCDRRR--TTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXX 126
+ N+ V +T+ F++ V+ D+NDN P + Y + E
Sbjct: 419 VSSYNITVTATDGGSPPLSTEAHFMLQVA----DINDNPPTFSQVSYFTYIPENNARGAS 474
Query: 127 XXXXXXSDRDQPGP----HSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFT 182
D D +S + P S Y+ ++ ++ + D+E +
Sbjct: 475 IFSVTALDPDSKENAQIIYSLAEDTIQGVPLSSYISINSDTG-VLYALRSFDYEQFHELQ 533
Query: 183 IKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFL---TTSPG 239
+++ D G PPL S+ +L + VLD +D P+ Y LP D G L + PG
Sbjct: 534 MQVTASDSGDPPLSSNVSLSLFVLDQNDNAPEILY----PALPTDGSTGVELAPRSAEPG 589
Query: 240 ----PISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLK 294
+ A D+D G NA L Y L V + TG+V + L+ ++V+
Sbjct: 590 YLVTKVVAVDRDSGQNAWLSYRLLKASEPGLFAVGEHTGEVRTARALLDRDALKQSLVVA 649
Query: 295 ATQVDNPDRYALATL 309
P A TL
Sbjct: 650 VQDHGQPPLSATVTL 664
Score = 58.8 bits (136), Expect = 8e-08
Identities = 56/216 (25%), Positives = 90/216 (41%), Gaps = 16/216 (7%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRD--QPGPHSALHYAVLPG 151
V + V DVNDN+P+ V+E D D Q G + A LP
Sbjct: 337 VLITVEDVNDNSPELTITSLFSPVTEDSPLGTVVALLNVHDLDSEQNGQVTCSILAYLPF 396
Query: 152 PHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQ 211
+ + L V+ + LD E V+++ I + D GSPPL ++ + V D +D
Sbjct: 397 KLEKSIDSYYRL----VIHRALDREQVSSYNITVTATDGGSPPLSTEAHFMLQVADINDN 452
Query: 212 NPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQ------L 265
P F+ Y +P++ G + + ++A D D NA + YS D Q
Sbjct: 453 PPTFSQVSYFTYIPENNARGASIFS----VTALDPDSKENAQIIYSLAEDTIQGVPLSSY 508
Query: 266 IVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNP 301
I +N DTG + A + E + + + A+ +P
Sbjct: 509 ISINSDTGVLYALRSFDYEQFHELQMQVTASDSGDP 544
Score = 34.3 bits (75), Expect = 2.0
Identities = 31/127 (24%), Positives = 50/127 (39%), Gaps = 9/127 (7%)
Query: 92 IPVSVRVWDVNDNAPQ-------WEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSAL 144
+ +S+ V D NDNAP+ +G+ + DRD G ++ L
Sbjct: 550 VSLSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDS-GQNAWL 608
Query: 145 HYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVT 204
Y +L + + LD + + ++ + VQD G PPL + TL V
Sbjct: 609 SYRLLKASEPGLFAVGEHTGEVRTARALLDRDALKQ-SLVVAVQDHGQPPLSATVTLTVA 667
Query: 205 VLDADDQ 211
V D+ Q
Sbjct: 668 VADSIPQ 674
>BC093873-1|AAH93873.1| 850|Homo sapiens protocadherin gamma
subfamily A, 10 protein.
Length = 850
Score = 91.1 bits (216), Expect = 2e-17
Identities = 112/444 (25%), Positives = 184/444 (41%), Gaps = 34/444 (7%)
Query: 8 SFFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAA--VGIVPGSKNLTLLRALD 64
S+ I E+ GS +G +S + G +L + +R+ +G + P S +L +D
Sbjct: 36 SYSIPEELEKGSFVGNISKDLGLAPRELAERGVRIVSRGRTQLFSLNPRSGSLVTAGRID 95
Query: 65 REEKIGPSN---VYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETX 121
REE S V N+ + R + + + V D+NDNAP+++ V+++E
Sbjct: 96 REELCAQSARCVVSFNILVEDRVK-----LFGIEIEVTDINDNAPKFQAENLDVKINENV 150
Query: 122 XXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYL--GFENELE-PIIVVKKPLDFETV 178
D D G +S Y + P H N ++ P +V++ LD E
Sbjct: 151 AAGMRFPLPEAIDPDV-GVNSLQSYQLSPNKHFSLRVQSRANGVKYPELVLEHSLDREEE 209
Query: 179 NNFTIKLRVQDQGSPPLYSDTTL-QVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTS 237
+ L D G PL S T L VTV DA+D P FT Y +P++ GT L T
Sbjct: 210 AIHHLVLTASD-GGDPLRSGTVLVSVTVFDANDNAPVFTLPEYRVSVPENLPVGTQLLT- 267
Query: 238 PGPISAADQDLGINAPLQYS--STGDHKQL-IVVNKDTGQVAATKQLIAELDPSVTIVLK 294
++A D+D G N + YS D + L +NK TG++ ++ L E I ++
Sbjct: 268 ---VTATDRDEGANGEVTYSFRKLPDTQLLKFQLNKYTGEIKISENLDYEETGFYEIEIQ 324
Query: 295 ATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVP 354
A A L + T + V+E + G+V+ L
Sbjct: 325 AED-------GGAYLATAKVLITVEDVNDNSPELTITSLFSPVTEDSPLGTVVALLNVHD 377
Query: 355 QNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSIS---N 411
++E ++ F + +I++ +++ R+LD E S+Y V TD S +
Sbjct: 378 LDSEQNGQVTCSILAYLPFKLEKSIDSYYRLVIHRALDREQVSSYNITVTATDGGSPPLS 437
Query: 412 DTASINISVEDVNEWEPRFRHPQY 435
A + V D+N+ P F Y
Sbjct: 438 TEAHFMLQVADINDNPPTFSQVSY 461
Score = 80.2 bits (189), Expect = 3e-14
Identities = 76/315 (24%), Positives = 128/315 (40%), Gaps = 26/315 (8%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQE--KGAAVGIVPGSKNLTLLRALDREEK 68
++ED+P+G+++ L+V+ SE G +T + + L + RALDRE+
Sbjct: 360 VTEDSPLGTVVALLNVHDLDSEQNGQVTCSILAYLPFKLEKSIDSYYRLVIHRALDREQ- 418
Query: 69 IGPSNVYVNVRCDRRR--TTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXX 126
+ N+ V +T+ F++ V+ D+NDN P + Y + E
Sbjct: 419 VSSYNITVTATDGGSPPLSTEAHFMLQVA----DINDNPPTFSQVSYFTYIPENNARGAS 474
Query: 127 XXXXXXSDRDQPGP----HSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFT 182
D D +S + P S Y+ ++ ++ + D+E +
Sbjct: 475 IFSVTALDPDSKENAQIIYSLAEDTIQGVPLSSYISINSDTG-VLYALRSFDYEQFHELQ 533
Query: 183 IKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFL---TTSPG 239
+++ D G PPL S+ +L + VLD +D P+ Y LP D G L + PG
Sbjct: 534 MQVTASDSGDPPLSSNVSLSLFVLDQNDNAPEILY----PALPTDGSTGVELAPRSAEPG 589
Query: 240 ----PISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLK 294
+ A D+D G NA L Y L V + TG+V + L+ ++V+
Sbjct: 590 YLVTKVVAVDRDSGQNAWLSYRLLKASEPGLFAVGEHTGEVRTARALLDRDALKQSLVVA 649
Query: 295 ATQVDNPDRYALATL 309
P A TL
Sbjct: 650 VQDHGQPPLSATVTL 664
Score = 58.8 bits (136), Expect = 8e-08
Identities = 56/216 (25%), Positives = 90/216 (41%), Gaps = 16/216 (7%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRD--QPGPHSALHYAVLPG 151
V + V DVNDN+P+ V+E D D Q G + A LP
Sbjct: 337 VLITVEDVNDNSPELTITSLFSPVTEDSPLGTVVALLNVHDLDSEQNGQVTCSILAYLPF 396
Query: 152 PHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQ 211
+ + L V+ + LD E V+++ I + D GSPPL ++ + V D +D
Sbjct: 397 KLEKSIDSYYRL----VIHRALDREQVSSYNITVTATDGGSPPLSTEAHFMLQVADINDN 452
Query: 212 NPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQ------L 265
P F+ Y +P++ G + + ++A D D NA + YS D Q
Sbjct: 453 PPTFSQVSYFTYIPENNARGASIFS----VTALDPDSKENAQIIYSLAEDTIQGVPLSSY 508
Query: 266 IVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNP 301
I +N DTG + A + E + + + A+ +P
Sbjct: 509 ISINSDTGVLYALRSFDYEQFHELQMQVTASDSGDP 544
Score = 34.3 bits (75), Expect = 2.0
Identities = 31/127 (24%), Positives = 50/127 (39%), Gaps = 9/127 (7%)
Query: 92 IPVSVRVWDVNDNAPQ-------WEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSAL 144
+ +S+ V D NDNAP+ +G+ + DRD G ++ L
Sbjct: 550 VSLSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDS-GQNAWL 608
Query: 145 HYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVT 204
Y +L + + LD + + ++ + VQD G PPL + TL V
Sbjct: 609 SYRLLKASEPGLFAVGEHTGEVRTARALLDRDALKQ-SLVVAVQDHGQPPLSATVTLTVA 667
Query: 205 VLDADDQ 211
V D+ Q
Sbjct: 668 VADSIPQ 674
>AF152486-1|AAD43747.1| 814|Homo sapiens protocadherin alpha 8
short form protein protein.
Length = 814
Score = 91.1 bits (216), Expect = 2e-17
Identities = 101/389 (25%), Positives = 159/389 (40%), Gaps = 34/389 (8%)
Query: 63 LDREEKIGPS---NVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSE 119
+DREE G S ++++ V DR P V V V V DVNDN P + + VSE
Sbjct: 90 IDREELCGRSAECSIHLEVIVDR-----PLQVFHVDVEVKDVNDNPPVFRVKDQKLFVSE 144
Query: 120 TXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYL------GFENELEPIIVVKKPL 173
+ SD D G +S L Y + H ++ EN+L +V++K L
Sbjct: 145 SRMPDSRFPLEGASDAD-VGANSVLTYRL--SSHDYFMLDVNSKNDENKLVE-LVLRKSL 200
Query: 174 DFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTF 233
D E + L D G P L L VTVLD +D P F Y + ++A+ GT
Sbjct: 201 DREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEVRIFENADNGTT 260
Query: 234 LTTSPGPISAADQDLGINAPLQYSSTGDHKQLIV----VNKDTGQVAATKQLIAELDPSV 289
+ ++A+D D G N + YS + +++ ++++TG++ L E +
Sbjct: 261 VI----KLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTGEIVIRGNLDFEQENLY 316
Query: 290 TIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLT 349
I++ AT +P T+ + S V E A G+V+
Sbjct: 317 KILIDATDKGHPPMAGHCTVLVRILDKNDNVP-----EIALTSLSLPVREDAQFGTVIAL 371
Query: 350 LTTVPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSI 409
++ ++ + F N ++L +LD E S Y V D
Sbjct: 372 ISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYELVVTARDGG 431
Query: 410 SND---TASINISVEDVNEWEPRFRHPQY 435
S TAS+++ V DVN+ P F P+Y
Sbjct: 432 SPSLWATASLSVEVADVNDNAPAFAQPEY 460
Score = 89.0 bits (211), Expect = 7e-17
Identities = 93/390 (23%), Positives = 164/390 (42%), Gaps = 26/390 (6%)
Query: 57 LTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVR 116
L L ++LDRE+ P++ D + + + + + V V DVNDNAP +E + Y VR
Sbjct: 194 LVLRKSLDRED--APAHHLFLTATDGGKP-ELTGTVQLLVTVLDVNDNAPTFEQSEYEVR 250
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYA---VLPGPHSEYLGFENELEPIIVVKKPL 173
+ E SD D+ G + A+ Y+ ++ ++ + I V++ L
Sbjct: 251 IFENADNGTTVIKLNASDPDE-GANGAISYSFNSLVETMVIDHFSIDRNTGEI-VIRGNL 308
Query: 174 DFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTF 233
DFE N + I + D+G PP+ T+ V +LD +D P+ + + +DA+ GT
Sbjct: 309 DFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTV 368
Query: 234 LTTSPGPISAADQDLGINAPLQYSSTGDHK-QLIVVNKDTGQVAATKQLIAELDPSVTIV 292
+ IS D D G N + S +L+ K+ + L E + +V
Sbjct: 369 IAL----ISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYELV 424
Query: 293 LKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTT 352
+ A +P +A A+L F Q +Y+ V E PG + T++
Sbjct: 425 VTARDGGSPSLWATASLSVEVADVNDNAPA-----FAQPEYTVFVKENNPPGCHIFTVSA 479
Query: 353 ----VPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTD 407
+N S ++ V +RS +++ +G+V + LD+E +QV D
Sbjct: 480 RDADAQENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARD 539
Query: 408 S---ISNDTASINISVEDVNEWEPRFRHPQ 434
+ ++ + V D N+ P P+
Sbjct: 540 AGVPPLGSNVTLQVFVLDENDNAPALLEPR 569
Score = 69.7 bits (163), Expect = 4e-11
Identities = 87/318 (27%), Positives = 124/318 (38%), Gaps = 30/318 (9%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKN---LTLLRALDREE 67
+ ED G++I +SVN S G +T L +V KN L L ALDR E
Sbjct: 359 VREDAQFGTVIALISVNDLDSGANGQVTCSLMPH-VPFKLVSTFKNYYSLVLDSALDR-E 416
Query: 68 KIGPSNVYVNVRCDRRRTTDPSF--VIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXX 125
++ + V R PS +SV V DVNDNAP + Y V V E
Sbjct: 417 RVSAYELVVTA----RDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGC 472
Query: 126 XXXXXXXSDRDQPG----PHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNF 181
D D +S + V S Y+ E + + +PLD E +
Sbjct: 473 HIFTVSARDADAQENALVSYSLVERRVGERSLSSYISVHTESGKVYAL-QPLDHEELELL 531
Query: 182 TIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKF-------TYEHYTALLPDDAEEGTFL 234
++ +D G PPL S+ TLQV VLD +D P T + L+P G +
Sbjct: 532 QFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVV 591
Query: 235 TTSPGPISAADQDLGINAPLQYS---STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTI 291
+ A D D G NA L Y + + V TG+++ T+ L P +
Sbjct: 592 ----AKVRAVDADSGYNAWLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRL 647
Query: 292 VLKATQVDNPDRYALATL 309
++ P A AT+
Sbjct: 648 LVLVKDHGEPALTATATV 665
Score = 32.7 bits (71), Expect = 6.0
Identities = 19/60 (31%), Positives = 30/60 (50%), Gaps = 3/60 (5%)
Query: 380 NNAGEVILRRSLDYETTSNYFYQVMVTDSISND---TASINISVEDVNEWEPRFRHPQYE 436
N E++LR+SLD E + + TD + T + ++V DVN+ P F +YE
Sbjct: 189 NKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYE 248
>AF152482-1|AAD43743.1| 798|Homo sapiens protocadherin alpha 4
short form protein protein.
Length = 798
Score = 91.1 bits (216), Expect = 2e-17
Identities = 110/446 (24%), Positives = 182/446 (40%), Gaps = 37/446 (8%)
Query: 9 FFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAAVGIVPGSKN--LTLLRALDR 65
+ +SE+ G+ +G ++ + G +L R+ KG + +N L + +DR
Sbjct: 33 YSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKGRGGLLEVNLQNGILFVNSRIDR 92
Query: 66 EE---KIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXX 122
EE + ++++ V DR P V V V V D+NDN P + + ++E+
Sbjct: 93 EELCRRSAECSIHLEVIVDR-----PLQVFHVDVEVRDINDNPPVFPATQKNLSIAESRP 147
Query: 123 XXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIV------VKKPLDFE 176
SD D G ++ L Y + P +EY E + +V ++K LD E
Sbjct: 148 LDSRFPLEGASDADI-GENALLTYRLSP---NEYFSLEKPPDDELVKGLGLILRKSLDRE 203
Query: 177 TVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTT 236
+ L D G P L L +TVLDA+D P F Y L ++ GT +
Sbjct: 204 EAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAFDRTIYKVRLLENVPNGTLVI- 262
Query: 237 SPGPISAADQDLGINAPLQYSSTGD----HKQLIVVNKDTGQVAATKQLIAELDPSVTIV 292
++A+D D G+N + YS + D K ++ TGQ+ + E S I+
Sbjct: 263 ---KLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQIIVKGYIDFEESKSYEII 319
Query: 293 LKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTT 352
++ +D + L+ L+F K S + E A G+V+ ++
Sbjct: 320 VEG--IDK-GQLPLSGHCRVIVEVEDNNDNVPDLEF--KSLSLPIREDAPLGTVIALISV 374
Query: 353 VPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSISND 412
++ S F N ++L +LD E+ S Y V D S
Sbjct: 375 SDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS 434
Query: 413 ---TASINISVEDVNEWEPRFRHPQY 435
TAS+++ V DVN+ P F P+Y
Sbjct: 435 LWATASVSVEVADVNDNAPAFAQPEY 460
Score = 78.6 bits (185), Expect = 9e-14
Identities = 91/390 (23%), Positives = 164/390 (42%), Gaps = 26/390 (6%)
Query: 57 LTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVR 116
L L ++LDREE P V D + + + + + + V D NDNAP ++ Y VR
Sbjct: 194 LILRKSLDREE--APEIFLVLTATDGGKP-ELTGTVQLLITVLDANDNAPAFDRTIYKVR 250
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPI---IVVKKPL 173
+ E SD D+ G + + Y+ S + + ++PI I+VK +
Sbjct: 251 LLENVPNGTLVIKLNASDLDE-GLNGDIVYS-FSNDISPNVKSKFHIDPITGQIIVKGYI 308
Query: 174 DFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTF 233
DFE ++ I + D+G PL + V V D +D P ++ + + +DA GT
Sbjct: 309 DFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIREDAPLGTV 368
Query: 234 LTTSPGPISAADQDLGINAPLQYSSTGDHK-QLIVVNKDTGQVAATKQLIAELDPSVTIV 292
+ IS +D+D+G+N + S T +L+ K+ + L E + +V
Sbjct: 369 IAL----ISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYELV 424
Query: 293 LKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTT 352
+ A +P +A A++ F Q +Y+ V E PG + T++
Sbjct: 425 VTARDGGSPSLWATASVSVEVADVNDNAPA-----FAQPEYTVFVKENNPPGCHIFTVSA 479
Query: 353 ----VPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTD 407
+N S ++ V +R+ +++ +G+V + LD+E +QV D
Sbjct: 480 WDADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARD 539
Query: 408 S---ISNDTASINISVEDVNEWEPRFRHPQ 434
+ ++ + V D N+ P P+
Sbjct: 540 AGVPPLGSNVTLQVFVLDENDNAPALLAPR 569
Score = 70.1 bits (164), Expect = 3e-11
Identities = 90/318 (28%), Positives = 125/318 (39%), Gaps = 30/318 (9%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKN---LTLLRALDREE 67
I ED P+G++I +SV+ G +T L +V KN L L ALDRE
Sbjct: 359 IREDAPLGTVIALISVSDKDMGVNGLVTCSLTSH-VPFKLVSTFKNYYSLVLDSALDRES 417
Query: 68 KIGPSNVYVNVRCDRRRTTDPSF--VIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXX 125
+ + V R PS VSV V DVNDNAP + Y V V E
Sbjct: 418 -VSAYELVVTARDGG----SPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGC 472
Query: 126 XXXXXXXSDRDQPG----PHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNF 181
D D +S + V S Y+ E + ++ PLD E +
Sbjct: 473 HIFTVSAWDADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQ-PLDHEELELL 531
Query: 182 TIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKF-------TYEHYTALLPDDAEEGTFL 234
++ +D G PPL S+ TLQV VLD +D P T + L+P G +
Sbjct: 532 QFQVTARDAGVPPLGSNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVV 591
Query: 235 TTSPGPISAADQDLGINAPLQYS---STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTI 291
+ A D D G NA L Y TG + V TG+++ T+ L P +
Sbjct: 592 ----AKVRAVDADSGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRL 647
Query: 292 VLKATQVDNPDRYALATL 309
++ P A AT+
Sbjct: 648 LVLVKDHGEPALTATATV 665
>AF152316-1|AAD43710.1| 950|Homo sapiens protocadherin alpha 8
protein.
Length = 950
Score = 91.1 bits (216), Expect = 2e-17
Identities = 101/389 (25%), Positives = 159/389 (40%), Gaps = 34/389 (8%)
Query: 63 LDREEKIGPS---NVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSE 119
+DREE G S ++++ V DR P V V V V DVNDN P + + VSE
Sbjct: 90 IDREELCGRSAECSIHLEVIVDR-----PLQVFHVDVEVKDVNDNPPVFRVKDQKLFVSE 144
Query: 120 TXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYL------GFENELEPIIVVKKPL 173
+ SD D G +S L Y + H ++ EN+L +V++K L
Sbjct: 145 SRMPDSRFPLEGASDAD-VGANSVLTYRL--SSHDYFMLDVNSKNDENKLVE-LVLRKSL 200
Query: 174 DFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTF 233
D E + L D G P L L VTVLD +D P F Y + ++A+ GT
Sbjct: 201 DREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEVRIFENADNGTT 260
Query: 234 LTTSPGPISAADQDLGINAPLQYSSTGDHKQLIV----VNKDTGQVAATKQLIAELDPSV 289
+ ++A+D D G N + YS + +++ ++++TG++ L E +
Sbjct: 261 VI----KLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTGEIVIRGNLDFEQENLY 316
Query: 290 TIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLT 349
I++ AT +P T+ + S V E A G+V+
Sbjct: 317 KILIDATDKGHPPMAGHCTVLVRILDKNDNVP-----EIALTSLSLPVREDAQFGTVIAL 371
Query: 350 LTTVPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSI 409
++ ++ + F N ++L +LD E S Y V D
Sbjct: 372 ISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYELVVTARDGG 431
Query: 410 SND---TASINISVEDVNEWEPRFRHPQY 435
S TAS+++ V DVN+ P F P+Y
Sbjct: 432 SPSLWATASLSVEVADVNDNAPAFAQPEY 460
Score = 89.0 bits (211), Expect = 7e-17
Identities = 93/390 (23%), Positives = 164/390 (42%), Gaps = 26/390 (6%)
Query: 57 LTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVR 116
L L ++LDRE+ P++ D + + + + + V V DVNDNAP +E + Y VR
Sbjct: 194 LVLRKSLDRED--APAHHLFLTATDGGKP-ELTGTVQLLVTVLDVNDNAPTFEQSEYEVR 250
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYA---VLPGPHSEYLGFENELEPIIVVKKPL 173
+ E SD D+ G + A+ Y+ ++ ++ + I V++ L
Sbjct: 251 IFENADNGTTVIKLNASDPDE-GANGAISYSFNSLVETMVIDHFSIDRNTGEI-VIRGNL 308
Query: 174 DFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTF 233
DFE N + I + D+G PP+ T+ V +LD +D P+ + + +DA+ GT
Sbjct: 309 DFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTV 368
Query: 234 LTTSPGPISAADQDLGINAPLQYSSTGDHK-QLIVVNKDTGQVAATKQLIAELDPSVTIV 292
+ IS D D G N + S +L+ K+ + L E + +V
Sbjct: 369 IAL----ISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYELV 424
Query: 293 LKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTT 352
+ A +P +A A+L F Q +Y+ V E PG + T++
Sbjct: 425 VTARDGGSPSLWATASLSVEVADVNDNAPA-----FAQPEYTVFVKENNPPGCHIFTVSA 479
Query: 353 ----VPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTD 407
+N S ++ V +RS +++ +G+V + LD+E +QV D
Sbjct: 480 RDADAQENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARD 539
Query: 408 S---ISNDTASINISVEDVNEWEPRFRHPQ 434
+ ++ + V D N+ P P+
Sbjct: 540 AGVPPLGSNVTLQVFVLDENDNAPALLEPR 569
Score = 69.7 bits (163), Expect = 4e-11
Identities = 87/318 (27%), Positives = 124/318 (38%), Gaps = 30/318 (9%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKN---LTLLRALDREE 67
+ ED G++I +SVN S G +T L +V KN L L ALDR E
Sbjct: 359 VREDAQFGTVIALISVNDLDSGANGQVTCSLMPH-VPFKLVSTFKNYYSLVLDSALDR-E 416
Query: 68 KIGPSNVYVNVRCDRRRTTDPSF--VIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXX 125
++ + V R PS +SV V DVNDNAP + Y V V E
Sbjct: 417 RVSAYELVVTA----RDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGC 472
Query: 126 XXXXXXXSDRDQPG----PHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNF 181
D D +S + V S Y+ E + + +PLD E +
Sbjct: 473 HIFTVSARDADAQENALVSYSLVERRVGERSLSSYISVHTESGKVYAL-QPLDHEELELL 531
Query: 182 TIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKF-------TYEHYTALLPDDAEEGTFL 234
++ +D G PPL S+ TLQV VLD +D P T + L+P G +
Sbjct: 532 QFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVV 591
Query: 235 TTSPGPISAADQDLGINAPLQYS---STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTI 291
+ A D D G NA L Y + + V TG+++ T+ L P +
Sbjct: 592 ----AKVRAVDADSGYNAWLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRL 647
Query: 292 VLKATQVDNPDRYALATL 309
++ P A AT+
Sbjct: 648 LVLVKDHGEPALTATATV 665
Score = 32.7 bits (71), Expect = 6.0
Identities = 19/60 (31%), Positives = 30/60 (50%), Gaps = 3/60 (5%)
Query: 380 NNAGEVILRRSLDYETTSNYFYQVMVTDSISND---TASINISVEDVNEWEPRFRHPQYE 436
N E++LR+SLD E + + TD + T + ++V DVN+ P F +YE
Sbjct: 189 NKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYE 248
>AF152312-1|AAD43706.1| 947|Homo sapiens protocadherin alpha 4
protein.
Length = 947
Score = 91.1 bits (216), Expect = 2e-17
Identities = 110/446 (24%), Positives = 182/446 (40%), Gaps = 37/446 (8%)
Query: 9 FFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAAVGIVPGSKN--LTLLRALDR 65
+ +SE+ G+ +G ++ + G +L R+ KG + +N L + +DR
Sbjct: 33 YSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKGRGGLLEVNLQNGILFVNSRIDR 92
Query: 66 EE---KIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXX 122
EE + ++++ V DR P V V V V D+NDN P + + ++E+
Sbjct: 93 EELCRRSAECSIHLEVIVDR-----PLQVFHVDVEVRDINDNPPVFPATQKNLSIAESRP 147
Query: 123 XXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIV------VKKPLDFE 176
SD D G ++ L Y + P +EY E + +V ++K LD E
Sbjct: 148 LDSRFPLEGASDADI-GENALLTYRLSP---NEYFSLEKPPDDELVKGLGLILRKSLDRE 203
Query: 177 TVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTT 236
+ L D G P L L +TVLDA+D P F Y L ++ GT +
Sbjct: 204 EAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAFDRTIYKVRLLENVPNGTLVI- 262
Query: 237 SPGPISAADQDLGINAPLQYSSTGD----HKQLIVVNKDTGQVAATKQLIAELDPSVTIV 292
++A+D D G+N + YS + D K ++ TGQ+ + E S I+
Sbjct: 263 ---KLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQIIVKGYIDFEESKSYEII 319
Query: 293 LKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTT 352
++ +D + L+ L+F K S + E A G+V+ ++
Sbjct: 320 VEG--IDK-GQLPLSGHCRVIVEVEDNNDNVPDLEF--KSLSLPIREDAPLGTVIALISV 374
Query: 353 VPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSISND 412
++ S F N ++L +LD E+ S Y V D S
Sbjct: 375 SDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS 434
Query: 413 ---TASINISVEDVNEWEPRFRHPQY 435
TAS+++ V DVN+ P F P+Y
Sbjct: 435 LWATASVSVEVADVNDNAPAFAQPEY 460
Score = 78.6 bits (185), Expect = 9e-14
Identities = 91/390 (23%), Positives = 164/390 (42%), Gaps = 26/390 (6%)
Query: 57 LTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVR 116
L L ++LDREE P V D + + + + + + V D NDNAP ++ Y VR
Sbjct: 194 LILRKSLDREE--APEIFLVLTATDGGKP-ELTGTVQLLITVLDANDNAPAFDRTIYKVR 250
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPI---IVVKKPL 173
+ E SD D+ G + + Y+ S + + ++PI I+VK +
Sbjct: 251 LLENVPNGTLVIKLNASDLDE-GLNGDIVYS-FSNDISPNVKSKFHIDPITGQIIVKGYI 308
Query: 174 DFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTF 233
DFE ++ I + D+G PL + V V D +D P ++ + + +DA GT
Sbjct: 309 DFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIREDAPLGTV 368
Query: 234 LTTSPGPISAADQDLGINAPLQYSSTGDHK-QLIVVNKDTGQVAATKQLIAELDPSVTIV 292
+ IS +D+D+G+N + S T +L+ K+ + L E + +V
Sbjct: 369 IAL----ISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYELV 424
Query: 293 LKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTT 352
+ A +P +A A++ F Q +Y+ V E PG + T++
Sbjct: 425 VTARDGGSPSLWATASVSVEVADVNDNAPA-----FAQPEYTVFVKENNPPGCHIFTVSA 479
Query: 353 ----VPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTD 407
+N S ++ V +R+ +++ +G+V + LD+E +QV D
Sbjct: 480 WDADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARD 539
Query: 408 S---ISNDTASINISVEDVNEWEPRFRHPQ 434
+ ++ + V D N+ P P+
Sbjct: 540 AGVPPLGSNVTLQVFVLDENDNAPALLAPR 569
Score = 70.1 bits (164), Expect = 3e-11
Identities = 90/318 (28%), Positives = 125/318 (39%), Gaps = 30/318 (9%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKN---LTLLRALDREE 67
I ED P+G++I +SV+ G +T L +V KN L L ALDRE
Sbjct: 359 IREDAPLGTVIALISVSDKDMGVNGLVTCSLTSH-VPFKLVSTFKNYYSLVLDSALDRES 417
Query: 68 KIGPSNVYVNVRCDRRRTTDPSF--VIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXX 125
+ + V R PS VSV V DVNDNAP + Y V V E
Sbjct: 418 -VSAYELVVTARDGG----SPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGC 472
Query: 126 XXXXXXXSDRDQPG----PHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNF 181
D D +S + V S Y+ E + ++ PLD E +
Sbjct: 473 HIFTVSAWDADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQ-PLDHEELELL 531
Query: 182 TIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKF-------TYEHYTALLPDDAEEGTFL 234
++ +D G PPL S+ TLQV VLD +D P T + L+P G +
Sbjct: 532 QFQVTARDAGVPPLGSNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVV 591
Query: 235 TTSPGPISAADQDLGINAPLQYS---STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTI 291
+ A D D G NA L Y TG + V TG+++ T+ L P +
Sbjct: 592 ----AKVRAVDADSGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRL 647
Query: 292 VLKATQVDNPDRYALATL 309
++ P A AT+
Sbjct: 648 LVLVKDHGEPALTATATV 665
>AC005609-10|AAC34322.1| 798|Homo sapiens KIAA0345-like 10 protein.
Length = 798
Score = 91.1 bits (216), Expect = 2e-17
Identities = 110/446 (24%), Positives = 182/446 (40%), Gaps = 37/446 (8%)
Query: 9 FFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAAVGIVPGSKN--LTLLRALDR 65
+ +SE+ G+ +G ++ + G +L R+ KG + +N L + +DR
Sbjct: 33 YSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKGRGGLLEVNLQNGILFVNSRIDR 92
Query: 66 EE---KIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXX 122
EE + ++++ V DR P V V V V D+NDN P + + ++E+
Sbjct: 93 EELCRRSAECSIHLEVIVDR-----PLQVFHVDVEVRDINDNPPVFPATQKNLSIAESRP 147
Query: 123 XXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIV------VKKPLDFE 176
SD D G ++ L Y + P +EY E + +V ++K LD E
Sbjct: 148 LDSRFPLEGASDADI-GENALLTYRLSP---NEYFSLEKPPDDELVKGLGLILRKSLDRE 203
Query: 177 TVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTT 236
+ L D G P L L +TVLDA+D P F Y L ++ GT +
Sbjct: 204 EAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAFDRTIYKVRLLENVPNGTLVI- 262
Query: 237 SPGPISAADQDLGINAPLQYSSTGD----HKQLIVVNKDTGQVAATKQLIAELDPSVTIV 292
++A+D D G+N + YS + D K ++ TGQ+ + E S I+
Sbjct: 263 ---KLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQIIVKGYIDFEESKSYEII 319
Query: 293 LKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTT 352
++ +D + L+ L+F K S + E A G+V+ ++
Sbjct: 320 VEG--IDK-GQLPLSGHCRVIVEVEDNNDNVPDLEF--KSLSLPIREDAPLGTVIALISV 374
Query: 353 VPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSISND 412
++ S F N ++L +LD E+ S Y V D S
Sbjct: 375 SDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS 434
Query: 413 ---TASINISVEDVNEWEPRFRHPQY 435
TAS+++ V DVN+ P F P+Y
Sbjct: 435 LWATASVSVEVADVNDNAPAFAQPEY 460
Score = 78.6 bits (185), Expect = 9e-14
Identities = 91/390 (23%), Positives = 164/390 (42%), Gaps = 26/390 (6%)
Query: 57 LTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVR 116
L L ++LDREE P V D + + + + + + V D NDNAP ++ Y VR
Sbjct: 194 LILRKSLDREE--APEIFLVLTATDGGKP-ELTGTVQLLITVLDANDNAPAFDRTIYKVR 250
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPI---IVVKKPL 173
+ E SD D+ G + + Y+ S + + ++PI I+VK +
Sbjct: 251 LLENVPNGTLVIKLNASDLDE-GLNGDIVYS-FSNDISPNVKSKFHIDPITGQIIVKGYI 308
Query: 174 DFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTF 233
DFE ++ I + D+G PL + V V D +D P ++ + + +DA GT
Sbjct: 309 DFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIREDAPLGTV 368
Query: 234 LTTSPGPISAADQDLGINAPLQYSSTGDHK-QLIVVNKDTGQVAATKQLIAELDPSVTIV 292
+ IS +D+D+G+N + S T +L+ K+ + L E + +V
Sbjct: 369 IAL----ISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYELV 424
Query: 293 LKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTT 352
+ A +P +A A++ F Q +Y+ V E PG + T++
Sbjct: 425 VTARDGGSPSLWATASVSVEVADVNDNAPA-----FAQPEYTVFVKENNPPGCHIFTVSA 479
Query: 353 ----VPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTD 407
+N S ++ V +R+ +++ +G+V + LD+E +QV D
Sbjct: 480 WDADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARD 539
Query: 408 S---ISNDTASINISVEDVNEWEPRFRHPQ 434
+ ++ + V D N+ P P+
Sbjct: 540 AGVPPLGSNVTLQVFVLDENDNAPALLAPR 569
Score = 70.1 bits (164), Expect = 3e-11
Identities = 90/318 (28%), Positives = 125/318 (39%), Gaps = 30/318 (9%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKN---LTLLRALDREE 67
I ED P+G++I +SV+ G +T L +V KN L L ALDRE
Sbjct: 359 IREDAPLGTVIALISVSDKDMGVNGLVTCSLTSH-VPFKLVSTFKNYYSLVLDSALDRES 417
Query: 68 KIGPSNVYVNVRCDRRRTTDPSF--VIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXX 125
+ + V R PS VSV V DVNDNAP + Y V V E
Sbjct: 418 -VSAYELVVTARDGG----SPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGC 472
Query: 126 XXXXXXXSDRDQPG----PHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNF 181
D D +S + V S Y+ E + ++ PLD E +
Sbjct: 473 HIFTVSAWDADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQ-PLDHEELELL 531
Query: 182 TIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKF-------TYEHYTALLPDDAEEGTFL 234
++ +D G PPL S+ TLQV VLD +D P T + L+P G +
Sbjct: 532 QFQVTARDAGVPPLGSNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVV 591
Query: 235 TTSPGPISAADQDLGINAPLQYS---STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTI 291
+ A D D G NA L Y TG + V TG+++ T+ L P +
Sbjct: 592 ----AKVRAVDADSGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRL 647
Query: 292 VLKATQVDNPDRYALATL 309
++ P A AT+
Sbjct: 648 LVLVKDHGEPALTATATV 665
>AC005609-6|AAC34318.1| 814|Homo sapiens KIAA0345-like 6 protein.
Length = 814
Score = 91.1 bits (216), Expect = 2e-17
Identities = 101/389 (25%), Positives = 159/389 (40%), Gaps = 34/389 (8%)
Query: 63 LDREEKIGPS---NVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSE 119
+DREE G S ++++ V DR P V V V V DVNDN P + + VSE
Sbjct: 90 IDREELCGRSAECSIHLEVIVDR-----PLQVFHVDVEVKDVNDNPPVFRVKDQKLFVSE 144
Query: 120 TXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYL------GFENELEPIIVVKKPL 173
+ SD D G +S L Y + H ++ EN+L +V++K L
Sbjct: 145 SRMPDSRFPLEGASDAD-VGANSVLTYRL--SSHDYFMLDVNSKNDENKLVE-LVLRKSL 200
Query: 174 DFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTF 233
D E + L D G P L L VTVLD +D P F Y + ++A+ GT
Sbjct: 201 DREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEVRIFENADNGTT 260
Query: 234 LTTSPGPISAADQDLGINAPLQYSSTGDHKQLIV----VNKDTGQVAATKQLIAELDPSV 289
+ ++A+D D G N + YS + +++ ++++TG++ L E +
Sbjct: 261 VI----KLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTGEIVIRGNLDFEQENLY 316
Query: 290 TIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLT 349
I++ AT +P T+ + S V E A G+V+
Sbjct: 317 KILIDATDKGHPPMAGHCTVLVRILDKNDNVP-----EIALTSLSLPVREDAQFGTVIAL 371
Query: 350 LTTVPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSI 409
++ ++ + F N ++L +LD E S Y V D
Sbjct: 372 ISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYELVVTARDGG 431
Query: 410 SND---TASINISVEDVNEWEPRFRHPQY 435
S TAS+++ V DVN+ P F P+Y
Sbjct: 432 SPSLWATASLSVEVADVNDNAPAFAQPEY 460
Score = 89.0 bits (211), Expect = 7e-17
Identities = 93/390 (23%), Positives = 164/390 (42%), Gaps = 26/390 (6%)
Query: 57 LTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVR 116
L L ++LDRE+ P++ D + + + + + V V DVNDNAP +E + Y VR
Sbjct: 194 LVLRKSLDRED--APAHHLFLTATDGGKP-ELTGTVQLLVTVLDVNDNAPTFEQSEYEVR 250
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYA---VLPGPHSEYLGFENELEPIIVVKKPL 173
+ E SD D+ G + A+ Y+ ++ ++ + I V++ L
Sbjct: 251 IFENADNGTTVIKLNASDPDE-GANGAISYSFNSLVETMVIDHFSIDRNTGEI-VIRGNL 308
Query: 174 DFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTF 233
DFE N + I + D+G PP+ T+ V +LD +D P+ + + +DA+ GT
Sbjct: 309 DFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTV 368
Query: 234 LTTSPGPISAADQDLGINAPLQYSSTGDHK-QLIVVNKDTGQVAATKQLIAELDPSVTIV 292
+ IS D D G N + S +L+ K+ + L E + +V
Sbjct: 369 IAL----ISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYELV 424
Query: 293 LKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTT 352
+ A +P +A A+L F Q +Y+ V E PG + T++
Sbjct: 425 VTARDGGSPSLWATASLSVEVADVNDNAPA-----FAQPEYTVFVKENNPPGCHIFTVSA 479
Query: 353 ----VPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTD 407
+N S ++ V +RS +++ +G+V + LD+E +QV D
Sbjct: 480 RDADAQENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARD 539
Query: 408 S---ISNDTASINISVEDVNEWEPRFRHPQ 434
+ ++ + V D N+ P P+
Sbjct: 540 AGVPPLGSNVTLQVFVLDENDNAPALLEPR 569
Score = 69.7 bits (163), Expect = 4e-11
Identities = 87/318 (27%), Positives = 124/318 (38%), Gaps = 30/318 (9%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKN---LTLLRALDREE 67
+ ED G++I +SVN S G +T L +V KN L L ALDR E
Sbjct: 359 VREDAQFGTVIALISVNDLDSGANGQVTCSLMPH-VPFKLVSTFKNYYSLVLDSALDR-E 416
Query: 68 KIGPSNVYVNVRCDRRRTTDPSF--VIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXX 125
++ + V R PS +SV V DVNDNAP + Y V V E
Sbjct: 417 RVSAYELVVTA----RDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGC 472
Query: 126 XXXXXXXSDRDQPG----PHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNF 181
D D +S + V S Y+ E + + +PLD E +
Sbjct: 473 HIFTVSARDADAQENALVSYSLVERRVGERSLSSYISVHTESGKVYAL-QPLDHEELELL 531
Query: 182 TIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKF-------TYEHYTALLPDDAEEGTFL 234
++ +D G PPL S+ TLQV VLD +D P T + L+P G +
Sbjct: 532 QFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVV 591
Query: 235 TTSPGPISAADQDLGINAPLQYS---STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTI 291
+ A D D G NA L Y + + V TG+++ T+ L P +
Sbjct: 592 ----AKVRAVDADSGYNAWLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRL 647
Query: 292 VLKATQVDNPDRYALATL 309
++ P A AT+
Sbjct: 648 LVLVKDHGEPALTATATV 665
Score = 32.7 bits (71), Expect = 6.0
Identities = 19/60 (31%), Positives = 30/60 (50%), Gaps = 3/60 (5%)
Query: 380 NNAGEVILRRSLDYETTSNYFYQVMVTDSISND---TASINISVEDVNEWEPRFRHPQYE 436
N E++LR+SLD E + + TD + T + ++V DVN+ P F +YE
Sbjct: 189 NKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYE 248
>AB208925-1|BAD92162.1| 921|Homo sapiens protocadherin alpha 4
isoform 1 precursor variant protein.
Length = 921
Score = 91.1 bits (216), Expect = 2e-17
Identities = 110/446 (24%), Positives = 182/446 (40%), Gaps = 37/446 (8%)
Query: 9 FFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAAVGIVPGSKN--LTLLRALDR 65
+ +SE+ G+ +G ++ + G +L R+ KG + +N L + +DR
Sbjct: 53 YSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKGRGGLLEVNLQNGILFVNSRIDR 112
Query: 66 EE---KIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXX 122
EE + ++++ V DR P V V V V D+NDN P + + ++E+
Sbjct: 113 EELCRRSAECSIHLEVIVDR-----PLQVFHVDVEVRDINDNPPVFPATQKNLSIAESRP 167
Query: 123 XXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIV------VKKPLDFE 176
SD D G ++ L Y + P +EY E + +V ++K LD E
Sbjct: 168 LDSRFPLEGASDADI-GENALLTYRLSP---NEYFSLEKPPDDELVKGLGLILRKSLDRE 223
Query: 177 TVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTT 236
+ L D G P L L +TVLDA+D P F Y L ++ GT +
Sbjct: 224 EAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAFDRTIYKVRLLENVPNGTLVI- 282
Query: 237 SPGPISAADQDLGINAPLQYSSTGD----HKQLIVVNKDTGQVAATKQLIAELDPSVTIV 292
++A+D D G+N + YS + D K ++ TGQ+ + E S I+
Sbjct: 283 ---KLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQIIVKGYIDFEESKSYEII 339
Query: 293 LKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTT 352
++ +D + L+ L+F K S + E A G+V+ ++
Sbjct: 340 VEG--IDK-GQLPLSGHCRVIVEVEDNNDNVPDLEF--KSLSLPIREDAPLGTVIALISV 394
Query: 353 VPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSISND 412
++ S F N ++L +LD E+ S Y V D S
Sbjct: 395 SDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS 454
Query: 413 ---TASINISVEDVNEWEPRFRHPQY 435
TAS+++ V DVN+ P F P+Y
Sbjct: 455 LWATASVSVEVADVNDNAPAFAQPEY 480
Score = 78.6 bits (185), Expect = 9e-14
Identities = 91/390 (23%), Positives = 164/390 (42%), Gaps = 26/390 (6%)
Query: 57 LTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVR 116
L L ++LDREE P V D + + + + + + V D NDNAP ++ Y VR
Sbjct: 214 LILRKSLDREE--APEIFLVLTATDGGKP-ELTGTVQLLITVLDANDNAPAFDRTIYKVR 270
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPI---IVVKKPL 173
+ E SD D+ G + + Y+ S + + ++PI I+VK +
Sbjct: 271 LLENVPNGTLVIKLNASDLDE-GLNGDIVYS-FSNDISPNVKSKFHIDPITGQIIVKGYI 328
Query: 174 DFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTF 233
DFE ++ I + D+G PL + V V D +D P ++ + + +DA GT
Sbjct: 329 DFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIREDAPLGTV 388
Query: 234 LTTSPGPISAADQDLGINAPLQYSSTGDHK-QLIVVNKDTGQVAATKQLIAELDPSVTIV 292
+ IS +D+D+G+N + S T +L+ K+ + L E + +V
Sbjct: 389 IAL----ISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYELV 444
Query: 293 LKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTT 352
+ A +P +A A++ F Q +Y+ V E PG + T++
Sbjct: 445 VTARDGGSPSLWATASVSVEVADVNDNAPA-----FAQPEYTVFVKENNPPGCHIFTVSA 499
Query: 353 ----VPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTD 407
+N S ++ V +R+ +++ +G+V + LD+E +QV D
Sbjct: 500 WDADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARD 559
Query: 408 S---ISNDTASINISVEDVNEWEPRFRHPQ 434
+ ++ + V D N+ P P+
Sbjct: 560 AGVPPLGSNVTLQVFVLDENDNAPALLAPR 589
Score = 70.1 bits (164), Expect = 3e-11
Identities = 90/318 (28%), Positives = 125/318 (39%), Gaps = 30/318 (9%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKN---LTLLRALDREE 67
I ED P+G++I +SV+ G +T L +V KN L L ALDRE
Sbjct: 379 IREDAPLGTVIALISVSDKDMGVNGLVTCSLTSH-VPFKLVSTFKNYYSLVLDSALDRES 437
Query: 68 KIGPSNVYVNVRCDRRRTTDPSF--VIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXX 125
+ + V R PS VSV V DVNDNAP + Y V V E
Sbjct: 438 -VSAYELVVTARDGG----SPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGC 492
Query: 126 XXXXXXXSDRDQPG----PHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNF 181
D D +S + V S Y+ E + ++ PLD E +
Sbjct: 493 HIFTVSAWDADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQ-PLDHEELELL 551
Query: 182 TIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKF-------TYEHYTALLPDDAEEGTFL 234
++ +D G PPL S+ TLQV VLD +D P T + L+P G +
Sbjct: 552 QFQVTARDAGVPPLGSNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVV 611
Query: 235 TTSPGPISAADQDLGINAPLQYS---STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTI 291
+ A D D G NA L Y TG + V TG+++ T+ L P +
Sbjct: 612 ----AKVRAVDADSGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRL 667
Query: 292 VLKATQVDNPDRYALATL 309
++ P A AT+
Sbjct: 668 LVLVKDHGEPALTATATV 685
>AF169694-1|AAF89691.1| 695|Homo sapiens protocadherin alpha 6
alternate isoform protein.
Length = 695
Score = 90.6 bits (215), Expect = 2e-17
Identities = 98/389 (25%), Positives = 158/389 (40%), Gaps = 34/389 (8%)
Query: 63 LDREEKIGPS---NVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSE 119
+DREE G S ++++ V DR P V V V V D+NDN P + V + E
Sbjct: 99 IDREELCGRSAECSIHLEVIVDR-----PLQVFHVDVEVRDINDNPPLFPVEEQRVLIYE 153
Query: 120 TXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPI------IVVKKPL 173
+ SD D G +S L Y + SEY G + ++ +++KK L
Sbjct: 154 SRLPDSVFPLEGASDAD-VGSNSILTYKL---SSSEYFGLDVKINSDDNKQIGLLLKKSL 209
Query: 174 DFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTF 233
D E + L D G P L L VTVLD +D P F Y + ++A+ GT
Sbjct: 210 DREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEVRIFENADNGTT 269
Query: 234 LTTSPGPISAADQDLGINAPLQYSSTGDHKQLIV----VNKDTGQVAATKQLIAELDPSV 289
+ ++A+D+D G N + YS +++ ++++TG++ L E +
Sbjct: 270 VIR----LNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNLDFEQENLY 325
Query: 290 TIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLT 349
I++ AT +P T+ + S V E A G+V+
Sbjct: 326 KILIDATDKGHPPMAGHCTVLVRILDKNDNVP-----EIALTSLSLPVREDAQFGTVIAL 380
Query: 350 LTTVPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSI 409
++ ++ F N ++L +LD E+ S Y V D
Sbjct: 381 ISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGG 440
Query: 410 SND---TASINISVEDVNEWEPRFRHPQY 435
S TAS+++ V D+N+ P F P+Y
Sbjct: 441 SPSLWATASLSVEVADMNDNAPAFAQPEY 469
Score = 90.2 bits (214), Expect = 3e-17
Identities = 87/347 (25%), Positives = 151/347 (43%), Gaps = 23/347 (6%)
Query: 57 LTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVR 116
L L ++LDREE P++ D + + + + + V V DVNDNAP +E + Y VR
Sbjct: 203 LLLKKSLDREE--APAHNLFLTATDGGKP-ELTGTVQLLVTVLDVNDNAPTFEQSEYEVR 259
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYA---VLPGPHSEYLGFENELEPIIVVKKPL 173
+ E SDRD+ G + A+ Y+ ++ ++ + I V++ L
Sbjct: 260 IFENADNGTTVIRLNASDRDE-GANGAISYSFNSLVAAMVIDHFSIDRNTGEI-VIRGNL 317
Query: 174 DFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTF 233
DFE N + I + D+G PP+ T+ V +LD +D P+ + + +DA+ GT
Sbjct: 318 DFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTV 377
Query: 234 LTTSPGPISAADQDLGINAPLQYSSTGDHK-QLIVVNKDTGQVAATKQLIAELDPSVTIV 292
+ IS D D G N + S T +L+ K+ + L E + +V
Sbjct: 378 IAL----ISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELV 433
Query: 293 LKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTT 352
+ A +P +A A+L F Q +Y+ V E PG + T++
Sbjct: 434 VTARDGGSPSLWATASLSVEVADMNDNAPA-----FAQPEYTVFVKENNPPGCHIFTVSA 488
Query: 353 ----VPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYE 394
+N S ++ V +R+ +++ +G+V + LD+E
Sbjct: 489 RDADAQENALVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHE 535
Score = 35.5 bits (78), Expect = 0.85
Identities = 37/114 (32%), Positives = 48/114 (42%), Gaps = 11/114 (9%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKN---LTLLRALDREE 67
+ ED G++I +SVN S G + L +V KN L L ALDR E
Sbjct: 368 VREDAQFGTVIALISVNDLDSGANGQVNCSLTPH-VPFKLVSTFKNYYSLVLDSALDR-E 425
Query: 68 KIGPSNVYVNVRCDRRRTTDPSF--VIPVSVRVWDVNDNAPQWEGAPYAVRVSE 119
+ + V R PS +SV V D+NDNAP + Y V V E
Sbjct: 426 SVSAYELVVTA----RDGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKE 475
>AF152503-1|AAD43764.1| 850|Homo sapiens protocadherin gamma A10
short form protein protein.
Length = 850
Score = 90.6 bits (215), Expect = 2e-17
Identities = 112/444 (25%), Positives = 184/444 (41%), Gaps = 34/444 (7%)
Query: 8 SFFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAA--VGIVPGSKNLTLLRALD 64
S+ I E+ GS +G +S + G +L + +R+ +G + P S +L +D
Sbjct: 36 SYSIPEELEKGSFVGNISKDLGLAPRELAERGVRIVSRGRTQLFSLNPRSGSLITAGRID 95
Query: 65 REEKIGPSN---VYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETX 121
REE S V N+ + R + + + V D+NDNAP+++ V+++E
Sbjct: 96 REELCAQSARCVVSFNILVEDRVK-----LFGIEIEVTDINDNAPKFQAENLDVKINENV 150
Query: 122 XXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYL--GFENELE-PIIVVKKPLDFETV 178
D D G +S Y + P H N ++ P +V++ LD E
Sbjct: 151 AAGMRFPLPEAIDPDV-GVNSLQSYQLSPNKHFSLRVQSRANGVKYPELVLEHSLDREEE 209
Query: 179 NNFTIKLRVQDQGSPPLYSDTTL-QVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTS 237
+ L D G PL S T L VTV DA+D P FT Y +P++ GT L T
Sbjct: 210 AIHHLVLTASD-GGDPLRSGTVLVSVTVFDANDNAPVFTLPEYRVSVPENLPVGTQLLT- 267
Query: 238 PGPISAADQDLGINAPLQYS--STGDHKQL-IVVNKDTGQVAATKQLIAELDPSVTIVLK 294
++A D+D G N + YS D + L +NK TG++ ++ L E I ++
Sbjct: 268 ---VTATDRDEGANGEVTYSFRKLPDTQLLKFQLNKYTGEIKISENLDYEETGFYEIEIQ 324
Query: 295 ATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVP 354
A A L + T + V+E + G+V+ L
Sbjct: 325 AED-------GGAYLATAKVLITVEDVNDNSPELTITSLFSPVTEDSPLGTVVALLNVHD 377
Query: 355 QNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSIS---N 411
++E ++ F + +I++ +++ R+LD E S+Y V TD S +
Sbjct: 378 LDSEQNGQVTCSILAYLPFKLEKSIDSYYRLVIHRALDREQVSSYNITVTATDGGSPPLS 437
Query: 412 DTASINISVEDVNEWEPRFRHPQY 435
A + V D+N+ P F Y
Sbjct: 438 TEAHFMLQVADINDNPPTFSQVSY 461
Score = 80.2 bits (189), Expect = 3e-14
Identities = 76/315 (24%), Positives = 128/315 (40%), Gaps = 26/315 (8%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQE--KGAAVGIVPGSKNLTLLRALDREEK 68
++ED+P+G+++ L+V+ SE G +T + + L + RALDRE+
Sbjct: 360 VTEDSPLGTVVALLNVHDLDSEQNGQVTCSILAYLPFKLEKSIDSYYRLVIHRALDREQ- 418
Query: 69 IGPSNVYVNVRCDRRR--TTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXX 126
+ N+ V +T+ F++ V+ D+NDN P + Y + E
Sbjct: 419 VSSYNITVTATDGGSPPLSTEAHFMLQVA----DINDNPPTFSQVSYFTYIPENNARGAS 474
Query: 127 XXXXXXSDRDQPGP----HSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFT 182
D D +S + P S Y+ ++ ++ + D+E +
Sbjct: 475 IFSVTALDPDSKENAQIIYSLAEDTIQGVPLSSYISINSDTG-VLYALRSFDYEQFHELQ 533
Query: 183 IKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFL---TTSPG 239
+++ D G PPL S+ +L + VLD +D P+ Y LP D G L + PG
Sbjct: 534 MQVTASDSGDPPLSSNVSLSLFVLDQNDNAPEILY----PALPTDGSTGVELAPRSAEPG 589
Query: 240 ----PISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLK 294
+ A D+D G NA L Y L V + TG+V + L+ ++V+
Sbjct: 590 YLVTKVVAVDRDSGQNAWLSYRLLKASEPGLFAVGEHTGEVRTARALLDRDALKQSLVVA 649
Query: 295 ATQVDNPDRYALATL 309
P A TL
Sbjct: 650 VQDHGQPPLSATVTL 664
Score = 58.8 bits (136), Expect = 8e-08
Identities = 56/216 (25%), Positives = 90/216 (41%), Gaps = 16/216 (7%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRD--QPGPHSALHYAVLPG 151
V + V DVNDN+P+ V+E D D Q G + A LP
Sbjct: 337 VLITVEDVNDNSPELTITSLFSPVTEDSPLGTVVALLNVHDLDSEQNGQVTCSILAYLPF 396
Query: 152 PHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQ 211
+ + L V+ + LD E V+++ I + D GSPPL ++ + V D +D
Sbjct: 397 KLEKSIDSYYRL----VIHRALDREQVSSYNITVTATDGGSPPLSTEAHFMLQVADINDN 452
Query: 212 NPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQ------L 265
P F+ Y +P++ G + + ++A D D NA + YS D Q
Sbjct: 453 PPTFSQVSYFTYIPENNARGASIFS----VTALDPDSKENAQIIYSLAEDTIQGVPLSSY 508
Query: 266 IVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNP 301
I +N DTG + A + E + + + A+ +P
Sbjct: 509 ISINSDTGVLYALRSFDYEQFHELQMQVTASDSGDP 544
Score = 34.3 bits (75), Expect = 2.0
Identities = 31/127 (24%), Positives = 50/127 (39%), Gaps = 9/127 (7%)
Query: 92 IPVSVRVWDVNDNAPQ-------WEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSAL 144
+ +S+ V D NDNAP+ +G+ + DRD G ++ L
Sbjct: 550 VSLSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDS-GQNAWL 608
Query: 145 HYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVT 204
Y +L + + LD + + ++ + VQD G PPL + TL V
Sbjct: 609 SYRLLKASEPGLFAVGEHTGEVRTARALLDRDALKQ-SLVVAVQDHGQPPLSATVTLTVA 667
Query: 205 VLDADDQ 211
V D+ Q
Sbjct: 668 VADSIPQ 674
>AF152319-1|AAD43713.1| 936|Homo sapiens protocadherin gamma A10
protein.
Length = 936
Score = 90.6 bits (215), Expect = 2e-17
Identities = 112/444 (25%), Positives = 184/444 (41%), Gaps = 34/444 (7%)
Query: 8 SFFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAA--VGIVPGSKNLTLLRALD 64
S+ I E+ GS +G +S + G +L + +R+ +G + P S +L +D
Sbjct: 36 SYSIPEELEKGSFVGNISKDLGLAPRELAERGVRIVSRGRTQLFSLNPRSGSLITAGRID 95
Query: 65 REEKIGPSN---VYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETX 121
REE S V N+ + R + + + V D+NDNAP+++ V+++E
Sbjct: 96 REELCAQSARCVVSFNILVEDRVK-----LFGIEIEVTDINDNAPKFQAENLDVKINENV 150
Query: 122 XXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYL--GFENELE-PIIVVKKPLDFETV 178
D D G +S Y + P H N ++ P +V++ LD E
Sbjct: 151 AAGMRFPLPEAIDPDV-GVNSLQSYQLSPNKHFSLRVQSRANGVKYPELVLEHSLDREEE 209
Query: 179 NNFTIKLRVQDQGSPPLYSDTTL-QVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTS 237
+ L D G PL S T L VTV DA+D P FT Y +P++ GT L T
Sbjct: 210 AIHHLVLTASD-GGDPLRSGTVLVSVTVFDANDNAPVFTLPEYRVSVPENLPVGTQLLT- 267
Query: 238 PGPISAADQDLGINAPLQYS--STGDHKQL-IVVNKDTGQVAATKQLIAELDPSVTIVLK 294
++A D+D G N + YS D + L +NK TG++ ++ L E I ++
Sbjct: 268 ---VTATDRDEGANGEVTYSFRKLPDTQLLKFQLNKYTGEIKISENLDYEETGFYEIEIQ 324
Query: 295 ATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVP 354
A A L + T + V+E + G+V+ L
Sbjct: 325 AED-------GGAYLATAKVLITVEDVNDNSPELTITSLFSPVTEDSPLGTVVALLNVHD 377
Query: 355 QNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSIS---N 411
++E ++ F + +I++ +++ R+LD E S+Y V TD S +
Sbjct: 378 LDSEQNGQVTCSILAYLPFKLEKSIDSYYRLVIHRALDREQVSSYNITVTATDGGSPPLS 437
Query: 412 DTASINISVEDVNEWEPRFRHPQY 435
A + V D+N+ P F Y
Sbjct: 438 TEAHFMLQVADINDNPPTFSQVSY 461
Score = 80.2 bits (189), Expect = 3e-14
Identities = 76/315 (24%), Positives = 128/315 (40%), Gaps = 26/315 (8%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQE--KGAAVGIVPGSKNLTLLRALDREEK 68
++ED+P+G+++ L+V+ SE G +T + + L + RALDRE+
Sbjct: 360 VTEDSPLGTVVALLNVHDLDSEQNGQVTCSILAYLPFKLEKSIDSYYRLVIHRALDREQ- 418
Query: 69 IGPSNVYVNVRCDRRR--TTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXX 126
+ N+ V +T+ F++ V+ D+NDN P + Y + E
Sbjct: 419 VSSYNITVTATDGGSPPLSTEAHFMLQVA----DINDNPPTFSQVSYFTYIPENNARGAS 474
Query: 127 XXXXXXSDRDQPGP----HSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFT 182
D D +S + P S Y+ ++ ++ + D+E +
Sbjct: 475 IFSVTALDPDSKENAQIIYSLAEDTIQGVPLSSYISINSDTG-VLYALRSFDYEQFHELQ 533
Query: 183 IKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFL---TTSPG 239
+++ D G PPL S+ +L + VLD +D P+ Y LP D G L + PG
Sbjct: 534 MQVTASDSGDPPLSSNVSLSLFVLDQNDNAPEILY----PALPTDGSTGVELAPRSAEPG 589
Query: 240 ----PISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLK 294
+ A D+D G NA L Y L V + TG+V + L+ ++V+
Sbjct: 590 YLVTKVVAVDRDSGQNAWLSYRLLKASEPGLFAVGEHTGEVRTARALLDRDALKQSLVVA 649
Query: 295 ATQVDNPDRYALATL 309
P A TL
Sbjct: 650 VQDHGQPPLSATVTL 664
Score = 58.8 bits (136), Expect = 8e-08
Identities = 56/216 (25%), Positives = 90/216 (41%), Gaps = 16/216 (7%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRD--QPGPHSALHYAVLPG 151
V + V DVNDN+P+ V+E D D Q G + A LP
Sbjct: 337 VLITVEDVNDNSPELTITSLFSPVTEDSPLGTVVALLNVHDLDSEQNGQVTCSILAYLPF 396
Query: 152 PHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQ 211
+ + L V+ + LD E V+++ I + D GSPPL ++ + V D +D
Sbjct: 397 KLEKSIDSYYRL----VIHRALDREQVSSYNITVTATDGGSPPLSTEAHFMLQVADINDN 452
Query: 212 NPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQ------L 265
P F+ Y +P++ G + + ++A D D NA + YS D Q
Sbjct: 453 PPTFSQVSYFTYIPENNARGASIFS----VTALDPDSKENAQIIYSLAEDTIQGVPLSSY 508
Query: 266 IVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNP 301
I +N DTG + A + E + + + A+ +P
Sbjct: 509 ISINSDTGVLYALRSFDYEQFHELQMQVTASDSGDP 544
Score = 34.3 bits (75), Expect = 2.0
Identities = 31/127 (24%), Positives = 50/127 (39%), Gaps = 9/127 (7%)
Query: 92 IPVSVRVWDVNDNAPQ-------WEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSAL 144
+ +S+ V D NDNAP+ +G+ + DRD G ++ L
Sbjct: 550 VSLSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDS-GQNAWL 608
Query: 145 HYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVT 204
Y +L + + LD + + ++ + VQD G PPL + TL V
Sbjct: 609 SYRLLKASEPGLFAVGEHTGEVRTARALLDRDALKQ-SLVVAVQDHGQPPLSATVTLTVA 667
Query: 205 VLDADDQ 211
V D+ Q
Sbjct: 668 VADSIPQ 674
>BC129807-1|AAI29808.1| 824|Homo sapiens protocadherin alpha 3
protein.
Length = 824
Score = 90.2 bits (214), Expect = 3e-17
Identities = 114/449 (25%), Positives = 187/449 (41%), Gaps = 43/449 (9%)
Query: 9 FFISEDTPIGSIIGTLSVNGDPSEDLGDITLRL-----QEKGAAVGIVPGSKNLTLLRAL 63
+ +SE+ G+ +G ++ D +L ++ RL + G + + + L + +
Sbjct: 33 YSVSEEAKHGTFVGRIAQ--DLGLELAELVPRLFRVASKRHGDLLEVNLQNGILFVNSRI 90
Query: 64 DREEKIGPS---NVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSET 120
DREE G S ++++ V DR P V V V V D+NDNAP + A + +SE+
Sbjct: 91 DREELCGRSAECSIHLEVIVDR-----PLQVFHVEVEVKDINDNAPVFPMAVKNLFISES 145
Query: 121 XXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFE-----NELEPI-IVVKKPLD 174
SD D G +S L Y++ +EY + E++ + +V+KK L+
Sbjct: 146 RQPGSRFSLEGASDADI-GTNSLLTYSL---DSTEYFTLDVKRNDEEIKSLGLVLKKNLN 201
Query: 175 FETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFL 234
E + + D G P L T L++TVLD +D P F Y L ++A GT +
Sbjct: 202 REDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAPAFERTIYKVRLLENAPNGTLV 261
Query: 235 TTSPGPISAADQDLGINAPLQYS----STGDHKQLIVVNKDTGQVAATKQLIAELDPSVT 290
T ++A D D G+N + YS + D ++ GQ++ + E S
Sbjct: 262 VT----VNATDLDEGVNKDIAYSFNTDMSADTLSKFHLDPVNGQISVKGNIDFEESKSYE 317
Query: 291 IVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTL 350
I ++AT NP T+ + + S V E SP S ++ L
Sbjct: 318 IQVEATDKGNPPMSDHCTVLLEIVDINDNVP-----ELVIQSLSLPVLED-SPLSTVIAL 371
Query: 351 TTVPQNTEFRESPLQFYVSDR-SFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSI 409
+V + ++ F N ++L LD E+ S Y V D
Sbjct: 372 ISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSAYELVVTARDGG 431
Query: 410 SND---TASINISVEDVNEWEPRFRHPQY 435
S TAS+++ V DVN+ P F +Y
Sbjct: 432 SPSLWATASVSVEVADVNDNAPAFSQSEY 460
Score = 83.0 bits (196), Expect = 4e-15
Identities = 80/353 (22%), Positives = 154/353 (43%), Gaps = 23/353 (6%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
+ + V DVNDNAP +E Y VR+ E +D D+ G + + Y+
Sbjct: 228 LKITVLDVNDNAPAFERTIYKVRLLENAPNGTLVVTVNATDLDE-GVNKDIAYSFNTDMS 286
Query: 154 SEYLGFENELEPI---IVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADD 210
++ L + L+P+ I VK +DFE ++ I++ D+G+PP+ T+ + ++D +D
Sbjct: 287 ADTLS-KFHLDPVNGQISVKGNIDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDIND 345
Query: 211 QNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHK-QLIVVN 269
P+ + + + +D+ L+T IS +D+D G+N + S T +L+
Sbjct: 346 NVPELVIQSLSLPVLEDSP----LSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTF 401
Query: 270 KDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFT 329
K+ + L E + +V+ A +P +A A++ F+
Sbjct: 402 KNYYSLVLDSPLDRESVSAYELVVTARDGGSPSLWATASVSVEVADVNDNAPA-----FS 456
Query: 330 QKQYSTTVSEGASPGSVLLTLTT----VPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGE 384
Q +Y+ V E PG + T++ +N S ++ V +R+ +++ +G+
Sbjct: 457 QSEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSLVERRVGERALSSYVSVHAESGK 516
Query: 385 VILRRSLDYETTSNYFYQVMVTDS---ISNDTASINISVEDVNEWEPRFRHPQ 434
V + LD+E +QV D+ ++ + V D N+ P P+
Sbjct: 517 VYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLMPR 569
Score = 71.3 bits (167), Expect = 1e-11
Identities = 87/318 (27%), Positives = 125/318 (39%), Gaps = 30/318 (9%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKN---LTLLRALDREE 67
+ ED+P+ ++I +SV+ S G +T L +V KN L L LDRE
Sbjct: 359 VLEDSPLSTVIALISVSDRDSGVNGQVTCSLTPH-VPFKLVSTFKNYYSLVLDSPLDRES 417
Query: 68 KIGPSNVYVNVRCDRRRTTDPSF--VIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXX 125
+ + V R PS VSV V DVNDNAP + + Y V V E
Sbjct: 418 -VSAYELVVTARDGG----SPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGC 472
Query: 126 XXXXXXXSDRDQPG----PHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNF 181
D D +S + V S Y+ E + ++ PLD E +
Sbjct: 473 HIFTVSARDADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQ-PLDHEELELL 531
Query: 182 TIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEH-------YTALLPDDAEEGTFL 234
++ +D G PPL S+ TLQV VLD +D P + L+P G +
Sbjct: 532 QFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVV 591
Query: 235 TTSPGPISAADQDLGINAPLQYS---STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTI 291
+ A D D G NA L Y TG + V TG+++ T+ L P +
Sbjct: 592 ----AKVRAVDADSGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRL 647
Query: 292 VLKATQVDNPDRYALATL 309
++ P A AT+
Sbjct: 648 LVLVKDHGEPSLTATATV 665
>BC051788-1|AAH51788.1| 929|Homo sapiens protocadherin gamma
subfamily B, 7 protein.
Length = 929
Score = 89.4 bits (212), Expect = 5e-17
Identities = 106/440 (24%), Positives = 179/440 (40%), Gaps = 30/440 (6%)
Query: 9 FFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREE 67
+ I E+ GS++G L+ + G D+ LR+ + + S +L + +DRE+
Sbjct: 35 YSIPEELAKGSVVGNLAKDLGLSVLDVSARELRVSAEKLHFSVDAQSGDLLVKDRIDREQ 94
Query: 68 KIGPSNVYVNVRCDRRRTT---DPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXX 124
RC+ + +P + V V + DVND+APQ+ + +SE+
Sbjct: 95 ICKERR-----RCELQLEAVVENPLNIFHVIVVIEDVNDHAPQFRKDEINLEISESVSLG 149
Query: 125 XXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENE---LEPIIVVKKPLDFETVNNF 181
D D +S Y + P + + +N P +V++K LD ET +
Sbjct: 150 MGTILESAEDPDI-SMNSLSKYQLSPNEYFSLVEKDNPDGGKYPELVLQKTLDRETQSAH 208
Query: 182 TIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPI 241
+ L D G PP +++ V+DA+D P F+ + Y L +D GT + +
Sbjct: 209 HLVLTALDGGDPPRSGTAQIRILVIDANDNPPVFSQDVYRVSLREDVPPGTSILR----V 264
Query: 242 SAADQDLGINAPLQYSSTG--DHKQ-LIVVNKDTGQVAATKQLIAELDPSVTIVLKATQV 298
A DQD GIN+ + YS G D Q + ++ TG + + L E TI ++A
Sbjct: 265 KATDQDEGINSEITYSFFGVADKAQHVFSLDYTTGNILTQQPLDFEEVERYTINIEA--- 321
Query: 299 DNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTE 358
DR +L+T + T S + E + PG V+ T Q++
Sbjct: 322 --KDRGSLSTRCKVIVEVVDENDNSPEIIIT--SLSDQIMEDSPPGVVVALFKTRDQDSG 377
Query: 359 FRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSIS---NDTAS 415
F + NN +++ +LD E T Y + TD + + +
Sbjct: 378 ENGEVRCSLSRGVPFKIHSSSNNYYKLVTDEALDREQTPEYNVTIAATDRGKPPLSSSKT 437
Query: 416 INISVEDVNEWEPRFRHPQY 435
I + + DVN+ P F Y
Sbjct: 438 ITLHITDVNDNAPVFGQSAY 457
Score = 73.3 bits (172), Expect = 3e-12
Identities = 80/314 (25%), Positives = 126/314 (40%), Gaps = 24/314 (7%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLL---RALDREE 67
I ED+P G ++ S + G++ L +G I S N L ALDRE+
Sbjct: 356 IMEDSPPGVVVALFKTRDQDSGENGEVRCSLS-RGVPFKIHSSSNNYYKLVTDEALDREQ 414
Query: 68 KIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXX 127
V + R S +++ + DVNDNAP + + Y V V E
Sbjct: 415 T---PEYNVTIAATDRGKPPLSSSKTITLHITDVNDNAPVFGQSAYLVHVPENNQPGASI 471
Query: 128 XXXXXSDRDQPGPHSALHYAVLPGPH-----SEYLGFENELEPIIVVKKPLDFETVNNFT 182
SD D G + + Y+++ S Y+ + ++ ++ D E + F
Sbjct: 472 AQVSASDPDF-GLNGRVSYSLIASDLESRTLSSYVSVSAQ-SGVVFAQRAFDHEQLRTFE 529
Query: 183 IKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAE--EGTFLTTSPG- 239
+ L+ +DQGSP L ++ +L+V V D +D P+ Y AL PD + + PG
Sbjct: 530 LTLQARDQGSPALSANVSLRVLVGDRNDNAPRVL---YPALGPDGSALFDTVPRAAQPGY 586
Query: 240 ---PISAADQDLGINAPLQYSST-GDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKA 295
+ A D D G NA L Y L + TG+V + L + +++
Sbjct: 587 LVTKVVAVDADSGHNAWLSYHVVQASEPGLFSLGLRTGEVRMVRALGDKDSVRQRLLVAV 646
Query: 296 TQVDNPDRYALATL 309
P A ATL
Sbjct: 647 RDGGQPPLSATATL 660
Score = 58.4 bits (135), Expect = 1e-07
Identities = 42/165 (25%), Positives = 72/165 (43%), Gaps = 8/165 (4%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPG-P 152
V V V D NDN+P+ + ++ E D+D G + + ++ G P
Sbjct: 333 VIVEVVDENDNSPEIIITSLSDQIMEDSPPGVVVALFKTRDQDS-GENGEVRCSLSRGVP 391
Query: 153 HSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQN 212
+ N + +V + LD E + + + D+G PPL S T+ + + D +D
Sbjct: 392 FKIHSSSNNYYK--LVTDEALDREQTPEYNVTIAATDRGKPPLSSSKTITLHITDVNDNA 449
Query: 213 PKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYS 257
P F Y +P++ + G S +SA+D D G+N + YS
Sbjct: 450 PVFGQSAYLVHVPENNQPG----ASIAQVSASDPDFGLNGRVSYS 490
>AF152523-1|AAD43783.1| 808|Homo sapiens protocadherin gamma B7
short form protein protein.
Length = 808
Score = 89.4 bits (212), Expect = 5e-17
Identities = 106/440 (24%), Positives = 179/440 (40%), Gaps = 30/440 (6%)
Query: 9 FFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREE 67
+ I E+ GS++G L+ + G D+ LR+ + + S +L + +DRE+
Sbjct: 35 YSIPEELAKGSVVGNLAKDLGLSVLDVSARELRVSAEKLHFSVDAQSGDLLVKDRIDREQ 94
Query: 68 KIGPSNVYVNVRCDRRRTT---DPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXX 124
RC+ + +P + V V + DVND+APQ+ + +SE+
Sbjct: 95 ICKERR-----RCELQLEAVVENPLNIFHVIVVIEDVNDHAPQFRKDEINLEISESVSLG 149
Query: 125 XXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENE---LEPIIVVKKPLDFETVNNF 181
D D +S Y + P + + +N P +V++K LD ET +
Sbjct: 150 MGTILESAEDPDI-SMNSLSKYQLSPNEYFSLVEKDNPDGGKYPELVLQKTLDRETQSAH 208
Query: 182 TIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPI 241
+ L D G PP +++ V+DA+D P F+ + Y L +D GT + +
Sbjct: 209 HLVLTALDGGDPPRSGTAQIRILVIDANDNPPVFSQDVYRVSLREDVPPGTSILR----V 264
Query: 242 SAADQDLGINAPLQYSSTG--DHKQ-LIVVNKDTGQVAATKQLIAELDPSVTIVLKATQV 298
A DQD GIN+ + YS G D Q + ++ TG + + L E TI ++A
Sbjct: 265 KATDQDEGINSEITYSFFGVADKAQHVFSLDYTTGNILTQQPLDFEEVERYTINIEA--- 321
Query: 299 DNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTE 358
DR +L+T + T S + E + PG V+ T Q++
Sbjct: 322 --KDRGSLSTRCKVIVEVVDENDNSPEIIIT--SLSDQIMEDSPPGVVVALFKTRDQDSG 377
Query: 359 FRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSIS---NDTAS 415
F + NN +++ +LD E T Y + TD + + +
Sbjct: 378 ENGEVRCSLSRGVPFKIHSSSNNYYKLVTDEALDREQTPEYNVTIAATDRGKPPLSSSKT 437
Query: 416 INISVEDVNEWEPRFRHPQY 435
I + + DVN+ P F Y
Sbjct: 438 ITLHITDVNDNAPVFGQSAY 457
Score = 73.3 bits (172), Expect = 3e-12
Identities = 80/314 (25%), Positives = 126/314 (40%), Gaps = 24/314 (7%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLL---RALDREE 67
I ED+P G ++ S + G++ L +G I S N L ALDRE+
Sbjct: 356 IMEDSPPGVVVALFKTRDQDSGENGEVRCSLS-RGVPFKIHSSSNNYYKLVTDEALDREQ 414
Query: 68 KIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXX 127
V + R S +++ + DVNDNAP + + Y V V E
Sbjct: 415 T---PEYNVTIAATDRGKPPLSSSKTITLHITDVNDNAPVFGQSAYLVHVPENNQPGASI 471
Query: 128 XXXXXSDRDQPGPHSALHYAVLPGPH-----SEYLGFENELEPIIVVKKPLDFETVNNFT 182
SD D G + + Y+++ S Y+ + ++ ++ D E + F
Sbjct: 472 AQVSASDPDF-GLNGRVSYSLIASDLESRTLSSYVSVSAQ-SGVVFAQRAFDHEQLRTFE 529
Query: 183 IKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAE--EGTFLTTSPG- 239
+ L+ +DQGSP L ++ +L+V V D +D P+ Y AL PD + + PG
Sbjct: 530 LTLQARDQGSPALSANVSLRVLVGDRNDNAPRVL---YPALGPDGSALFDTVPRAAQPGY 586
Query: 240 ---PISAADQDLGINAPLQYSST-GDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKA 295
+ A D D G NA L Y L + TG+V + L + +++
Sbjct: 587 LVTKVVAVDADSGHNAWLSYHVVQASEPGLFSLGLRTGEVRMVRALGDKDSVRQRLLVAV 646
Query: 296 TQVDNPDRYALATL 309
P A ATL
Sbjct: 647 RDGGQPPLSATATL 660
Score = 58.4 bits (135), Expect = 1e-07
Identities = 42/165 (25%), Positives = 72/165 (43%), Gaps = 8/165 (4%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPG-P 152
V V V D NDN+P+ + ++ E D+D G + + ++ G P
Sbjct: 333 VIVEVVDENDNSPEIIITSLSDQIMEDSPPGVVVALFKTRDQDS-GENGEVRCSLSRGVP 391
Query: 153 HSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQN 212
+ N + +V + LD E + + + D+G PPL S T+ + + D +D
Sbjct: 392 FKIHSSSNNYYK--LVTDEALDREQTPEYNVTIAATDRGKPPLSSSKTITLHITDVNDNA 449
Query: 213 PKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYS 257
P F Y +P++ + G S +SA+D D G+N + YS
Sbjct: 450 PVFGQSAYLVHVPENNQPG----ASIAQVSASDPDFGLNGRVSYS 490
>AF152336-1|AAD43730.1| 929|Homo sapiens protocadherin gamma B7
protein.
Length = 929
Score = 89.4 bits (212), Expect = 5e-17
Identities = 106/440 (24%), Positives = 179/440 (40%), Gaps = 30/440 (6%)
Query: 9 FFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREE 67
+ I E+ GS++G L+ + G D+ LR+ + + S +L + +DRE+
Sbjct: 35 YSIPEELAKGSVVGNLAKDLGLSVLDVSARELRVSAEKLHFSVDAQSGDLLVKDRIDREQ 94
Query: 68 KIGPSNVYVNVRCDRRRTT---DPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXX 124
RC+ + +P + V V + DVND+APQ+ + +SE+
Sbjct: 95 ICKERR-----RCELQLEAVVENPLNIFHVIVVIEDVNDHAPQFRKDEINLEISESVSLG 149
Query: 125 XXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENE---LEPIIVVKKPLDFETVNNF 181
D D +S Y + P + + +N P +V++K LD ET +
Sbjct: 150 MGTILESAEDPDI-SMNSLSKYQLSPNEYFSLVEKDNPDGGKYPELVLQKTLDRETQSAH 208
Query: 182 TIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPI 241
+ L D G PP +++ V+DA+D P F+ + Y L +D GT + +
Sbjct: 209 HLVLTALDGGDPPRSGTAQIRILVIDANDNPPVFSQDVYRVSLREDVPPGTSILR----V 264
Query: 242 SAADQDLGINAPLQYSSTG--DHKQ-LIVVNKDTGQVAATKQLIAELDPSVTIVLKATQV 298
A DQD GIN+ + YS G D Q + ++ TG + + L E TI ++A
Sbjct: 265 KATDQDEGINSEITYSFFGVADKAQHVFSLDYTTGNILTQQPLDFEEVERYTINIEA--- 321
Query: 299 DNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTE 358
DR +L+T + T S + E + PG V+ T Q++
Sbjct: 322 --KDRGSLSTRCKVIVEVVDENDNSPEIIIT--SLSDQIMEDSPPGVVVALFKTRDQDSG 377
Query: 359 FRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSIS---NDTAS 415
F + NN +++ +LD E T Y + TD + + +
Sbjct: 378 ENGEVRCSLSRGVPFKIHSSSNNYYKLVTDEALDREQTPEYNVTIAATDRGKPPLSSSKT 437
Query: 416 INISVEDVNEWEPRFRHPQY 435
I + + DVN+ P F Y
Sbjct: 438 ITLHITDVNDNAPVFGQSAY 457
Score = 73.3 bits (172), Expect = 3e-12
Identities = 80/314 (25%), Positives = 126/314 (40%), Gaps = 24/314 (7%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLL---RALDREE 67
I ED+P G ++ S + G++ L +G I S N L ALDRE+
Sbjct: 356 IMEDSPPGVVVALFKTRDQDSGENGEVRCSLS-RGVPFKIHSSSNNYYKLVTDEALDREQ 414
Query: 68 KIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXX 127
V + R S +++ + DVNDNAP + + Y V V E
Sbjct: 415 T---PEYNVTIAATDRGKPPLSSSKTITLHITDVNDNAPVFGQSAYLVHVPENNQPGASI 471
Query: 128 XXXXXSDRDQPGPHSALHYAVLPGPH-----SEYLGFENELEPIIVVKKPLDFETVNNFT 182
SD D G + + Y+++ S Y+ + ++ ++ D E + F
Sbjct: 472 AQVSASDPDF-GLNGRVSYSLIASDLESRTLSSYVSVSAQ-SGVVFAQRAFDHEQLRTFE 529
Query: 183 IKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAE--EGTFLTTSPG- 239
+ L+ +DQGSP L ++ +L+V V D +D P+ Y AL PD + + PG
Sbjct: 530 LTLQARDQGSPALSANVSLRVLVGDRNDNAPRVL---YPALGPDGSALFDTVPRAAQPGY 586
Query: 240 ---PISAADQDLGINAPLQYSST-GDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKA 295
+ A D D G NA L Y L + TG+V + L + +++
Sbjct: 587 LVTKVVAVDADSGHNAWLSYHVVQASEPGLFSLGLRTGEVRMVRALGDKDSVRQRLLVAV 646
Query: 296 TQVDNPDRYALATL 309
P A ATL
Sbjct: 647 RDGGQPPLSATATL 660
Score = 58.4 bits (135), Expect = 1e-07
Identities = 42/165 (25%), Positives = 72/165 (43%), Gaps = 8/165 (4%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPG-P 152
V V V D NDN+P+ + ++ E D+D G + + ++ G P
Sbjct: 333 VIVEVVDENDNSPEIIITSLSDQIMEDSPPGVVVALFKTRDQDS-GENGEVRCSLSRGVP 391
Query: 153 HSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQN 212
+ N + +V + LD E + + + D+G PPL S T+ + + D +D
Sbjct: 392 FKIHSSSNNYYK--LVTDEALDREQTPEYNVTIAATDRGKPPLSSSKTITLHITDVNDNA 449
Query: 213 PKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYS 257
P F Y +P++ + G S +SA+D D G+N + YS
Sbjct: 450 PVFGQSAYLVHVPENNQPG----ASIAQVSASDPDFGLNGRVSYS 490
>AF152323-1|AAD43717.1| 932|Homo sapiens protocadherin gamma A3
protein.
Length = 932
Score = 89.4 bits (212), Expect = 5e-17
Identities = 119/539 (22%), Positives = 213/539 (39%), Gaps = 39/539 (7%)
Query: 3 GGAVESFFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAA--VGIVPGSKNLTL 59
G + + +SE+ GS +G ++ + G +L + +R+ +G + P S +L
Sbjct: 27 GSSQIRYSVSEELDKGSFVGNIANDLGLEPRELAERGVRIVSRGRTQLFSLNPQSGSLVT 86
Query: 60 LRALDREE---KIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVR 116
+DREE +I V +N+ + D + V + + D+NDNAP + ++
Sbjct: 87 AERIDREELCAQIPLCLVKINILVE-----DKLKIFEVEIEIKDINDNAPNFPTEELEIK 141
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLG---FENELEPIIVVKKPL 173
+ E D D G +S +Y + P + E P +V+++ L
Sbjct: 142 IGELTVPGTRFPIKTAFDPDV-GINSLQNYKLSPNDYFSLAVNSVSEGAKYPELVLERAL 200
Query: 174 DFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTF 233
D E + L D G P + +QV VLDA+D P FT Y + ++ GT
Sbjct: 201 DREKKEIHQLVLVASDGGDPVHSGNLHIQVIVLDANDNPPMFTQPEYRVSVWENVPVGTR 260
Query: 234 LTTSPGPISAADQDLGINAPLQY---SSTGDHKQLIVVNKDTGQVAATKQLIAELDPSVT 290
L T ++A D D G NA + Y G ++ +N +G+V+ K L + + ++
Sbjct: 261 LLT----VNATDPDEGFNAQVSYILDKMPGKIAEIFHLNSVSGEVSILKSL--DYEDAMF 314
Query: 291 IVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTL 350
+K D P + A + + T +++V E + G + +
Sbjct: 315 YEIKIEAQDGPGLLSRAKILVTVLDVNDNAP-----EITITSLTSSVPEEGTVGREIALI 369
Query: 351 TTVPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDS-- 408
+++ F + + F + +I+ ++ SLD E S Y + +D
Sbjct: 370 DVHDRDSGQNGQVEVFVLGNLPFKLEKSIDQYYRLVTATSLDREQISEYNISLRASDGGS 429
Query: 409 --ISNDTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGDAG 466
+S +T I + V D+N+ P F H Y +++
Sbjct: 430 PPLSTET-HITLHVIDINDNPPTFPHLSYS-AYIPENNPRGASIFSVTAQDPDSNNNARI 487
Query: 467 TLAL---SLAGQHARMFY-INASGDLFLREEAIGNLNSSSLHLVATAIDSGIPPRQTSV 521
T AL +L G F IN++ + + L L+ TA DSG PP ++V
Sbjct: 488 TYALTEDTLQGAPLSSFVSINSNTGVLYALRSFDYEQFRDLKLLVTASDSGNPPLSSNV 546
Score = 64.5 bits (150), Expect = 2e-09
Identities = 66/266 (24%), Positives = 107/266 (40%), Gaps = 22/266 (8%)
Query: 57 LTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVR 116
L +LDRE+ S +++R + S +++ V D+NDN P + Y+
Sbjct: 404 LVTATSLDREQI---SEYNISLRASDGGSPPLSTETHITLHVIDINDNPPTFPHLSYSAY 460
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYAV----LPG-PHSEYLGFENELEPIIVVKK 171
+ E D D ++ + YA+ L G P S ++ N ++ +
Sbjct: 461 IPENNPRGASIFSVTAQDPDSNN-NARITYALTEDTLQGAPLSSFVSI-NSNTGVLYALR 518
Query: 172 PLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEG 231
D+E + + + D G+PPL S+ +L + VLD +D P+ Y LP D G
Sbjct: 519 SFDYEQFRDLKLLVTASDSGNPPLSSNVSLNLFVLDQNDNAPEILY----PALPTDGSTG 574
Query: 232 TFL---TTSPG----PISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIA 283
L + PG + A D+D G NA L Y L V TG+V + L+
Sbjct: 575 VELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRLLKASEPGLFSVGLHTGEVRTARALLD 634
Query: 284 ELDPSVTIVLKATQVDNPDRYALATL 309
++V+ P A TL
Sbjct: 635 RDALKQSLVVAIQDHGQPPLSATVTL 660
Score = 34.7 bits (76), Expect = 1.5
Identities = 48/211 (22%), Positives = 83/211 (39%), Gaps = 13/211 (6%)
Query: 8 SFFISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQE---KGAAVG-IVPGSKNLTLLRAL 63
S +I E+ P G+ I +++ S + IT L E +GA + V + N +L AL
Sbjct: 458 SAYIPENNPRGASIFSVTAQDPDSNNNARITYALTEDTLQGAPLSSFVSINSNTGVLYAL 517
Query: 64 DREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQ-------WEGAPYAVR 116
+ ++ + V S + +++ V D NDNAP+ +G+
Sbjct: 518 RSFDYEQFRDLKLLVTASDSGNPPLSSNVSLNLFVLDQNDNAPEILYPALPTDGSTGVEL 577
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFE 176
+ DRD G ++ L Y +L + + LD +
Sbjct: 578 APRSAEPGYLVTKVVAVDRDS-GQNAWLSYRLLKASEPGLFSVGLHTGEVRTARALLDRD 636
Query: 177 TVNNFTIKLRVQDQGSPPLYSDTTLQVTVLD 207
+ ++ + +QD G PPL + TL V V D
Sbjct: 637 ALKQ-SLVVAIQDHGQPPLSATVTLIVAVAD 666
>BC115409-1|AAI15410.1| 694|Homo sapiens PCDHGA3 protein protein.
Length = 694
Score = 89.0 bits (211), Expect = 7e-17
Identities = 118/533 (22%), Positives = 211/533 (39%), Gaps = 39/533 (7%)
Query: 9 FFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAA--VGIVPGSKNLTLLRALDR 65
+ +SE+ GS +G ++ + G +L + +R+ +G + P S +L +DR
Sbjct: 33 YSVSEELDKGSFVGNIANDLGLEPRELAERGVRIVSRGRTQLFSLNPQSGSLVTAERIDR 92
Query: 66 EE---KIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXX 122
EE +I V +N+ + D + V + + D+NDNAP + +++ E
Sbjct: 93 EELCAQIPLCLVKINILVE-----DKLKIFEVEIEIKDINDNAPNFPTEELEIKIGELTV 147
Query: 123 XXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLG---FENELEPIIVVKKPLDFETVN 179
D D G +S +Y + P + E P +V+++ LD E
Sbjct: 148 PGTRFPLKTAFDPDV-GINSLQNYKLSPNDYFSLAVNSVSEGAKYPELVLERALDREKKE 206
Query: 180 NFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPG 239
+ L D G P + +QV VLDA+D P FT Y + ++ GT L T
Sbjct: 207 IHQLVLVASDGGDPVHSGNLHIQVIVLDANDNPPMFTQPEYRVSVWENVPVGTRLLT--- 263
Query: 240 PISAADQDLGINAPLQY---SSTGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKAT 296
++A D D G NA + Y G ++ +N +G+V+ K L + + ++ +K
Sbjct: 264 -VNATDPDEGFNAQVSYILDKMPGKIAEIFHLNSVSGEVSILKSL--DYEDAMFYEIKIE 320
Query: 297 QVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQN 356
D P + A + + T +++V E + G + + ++
Sbjct: 321 AQDGPGLLSRAKILVTVLDVNDNAP-----EITITSLTSSVPEEGTVGREIALIDVHDRD 375
Query: 357 TEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDS----ISND 412
+ F + + F + +I+ ++ SLD E S Y + +D +S +
Sbjct: 376 SGQNGQVEVFVLGNLPFKLEKSIDQYYRLVTATSLDREQISEYNISLRASDGGSPPLSTE 435
Query: 413 TASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGDAGTLAL-- 470
T I + V D+N+ P F H Y +++ T AL
Sbjct: 436 T-HITLHVIDINDNPPTFPHLSYS-AYIPENNPRGASIFSVTAQDPDSNNNARITYALTE 493
Query: 471 -SLAGQHARMFY-INASGDLFLREEAIGNLNSSSLHLVATAIDSGIPPRQTSV 521
+L G F IN++ + + L L+ TA DSG PP ++V
Sbjct: 494 DTLQGAPLSSFVSINSNTGVLYALRSFDYEQFRDLKLLVTASDSGNPPLSSNV 546
Score = 64.9 bits (151), Expect = 1e-09
Identities = 66/266 (24%), Positives = 107/266 (40%), Gaps = 22/266 (8%)
Query: 57 LTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVR 116
L +LDRE+ S +++R + S +++ V D+NDN P + Y+
Sbjct: 404 LVTATSLDREQI---SEYNISLRASDGGSPPLSTETHITLHVIDINDNPPTFPHLSYSAY 460
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYAV----LPG-PHSEYLGFENELEPIIVVKK 171
+ E D D ++ + YA+ L G P S ++ N ++ +
Sbjct: 461 IPENNPRGASIFSVTAQDPDSNN-NARITYALTEDTLQGAPLSSFVSI-NSNTGVLYALR 518
Query: 172 PLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEG 231
D+E + + + D G+PPL S+ +L + VLD +D P+ Y LP D G
Sbjct: 519 SFDYEQFRDLKLLVTASDSGNPPLSSNVSLNLFVLDQNDNAPEILY----PALPTDGSTG 574
Query: 232 TFL---TTSPG----PISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIA 283
L + PG + A D+D G NA L Y L V TG+V + L+
Sbjct: 575 VELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRLLKASEPGLFSVGLHTGEVRTARALLD 634
Query: 284 ELDPSVTIVLKATQVDNPDRYALATL 309
++V+ P A TL
Sbjct: 635 RDALKQSLVVAVQDHGQPPLSATVTL 660
Score = 35.9 bits (79), Expect = 0.64
Identities = 49/211 (23%), Positives = 83/211 (39%), Gaps = 13/211 (6%)
Query: 8 SFFISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQE---KGAAVG-IVPGSKNLTLLRAL 63
S +I E+ P G+ I +++ S + IT L E +GA + V + N +L AL
Sbjct: 458 SAYIPENNPRGASIFSVTAQDPDSNNNARITYALTEDTLQGAPLSSFVSINSNTGVLYAL 517
Query: 64 DREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQ-------WEGAPYAVR 116
+ ++ + V S + +++ V D NDNAP+ +G+
Sbjct: 518 RSFDYEQFRDLKLLVTASDSGNPPLSSNVSLNLFVLDQNDNAPEILYPALPTDGSTGVEL 577
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFE 176
+ DRD G ++ L Y +L + + LD +
Sbjct: 578 APRSAEPGYLVTKVVAVDRDS-GQNAWLSYRLLKASEPGLFSVGLHTGEVRTARALLDRD 636
Query: 177 TVNNFTIKLRVQDQGSPPLYSDTTLQVTVLD 207
+ ++ + VQD G PPL + TL V V D
Sbjct: 637 ALKQ-SLVVAVQDHGQPPLSATVTLTVAVAD 666
>BC115408-1|AAI15409.1| 694|Homo sapiens PCDHGA3 protein protein.
Length = 694
Score = 89.0 bits (211), Expect = 7e-17
Identities = 118/533 (22%), Positives = 211/533 (39%), Gaps = 39/533 (7%)
Query: 9 FFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAA--VGIVPGSKNLTLLRALDR 65
+ +SE+ GS +G ++ + G +L + +R+ +G + P S +L +DR
Sbjct: 33 YSVSEELDKGSFVGNIANDLGLEPRELAERGVRIVSRGRTQLFSLNPQSGSLVTAERIDR 92
Query: 66 EE---KIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXX 122
EE +I V +N+ + D + V + + D+NDNAP + +++ E
Sbjct: 93 EELCAQIPLCLVKINILVE-----DKLKIFEVEIEIKDINDNAPNFPTEELEIKIGELTV 147
Query: 123 XXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLG---FENELEPIIVVKKPLDFETVN 179
D D G +S +Y + P + E P +V+++ LD E
Sbjct: 148 PGTRFPIKTAFDPDV-GINSLQNYKLSPNDYFSLAVNSVSEGAKYPELVLERALDREKKE 206
Query: 180 NFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPG 239
+ L D G P + +QV VLDA+D P FT Y + ++ GT L T
Sbjct: 207 IHQLVLVASDGGDPVHSGNLHIQVIVLDANDNPPMFTQPEYRVSVWENVPVGTRLLT--- 263
Query: 240 PISAADQDLGINAPLQY---SSTGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKAT 296
++A D D G NA + Y G ++ +N +G+V+ K L + + ++ +K
Sbjct: 264 -VNATDPDEGFNAQVSYILDKMPGKIAEIFHLNSVSGEVSILKSL--DYEDAMFYEIKIE 320
Query: 297 QVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQN 356
D P + A + + T +++V E + G + + ++
Sbjct: 321 AQDGPGLLSRAKILVTVLDVNDNAP-----EITITSLTSSVPEEGTVGREIALIDVHDRD 375
Query: 357 TEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDS----ISND 412
+ F + + F + +I+ ++ SLD E S Y + +D +S +
Sbjct: 376 SGQNGQVEVFVLGNLPFKLEKSIDQYYRLVTATSLDREQISEYNISLRASDGGSPPLSTE 435
Query: 413 TASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGDAGTLAL-- 470
T I + V D+N+ P F H Y +++ T AL
Sbjct: 436 T-HITLHVIDINDNPPTFPHLSYS-AYIPENNPRGASIFSVTAQDPDSNNNARITYALTE 493
Query: 471 -SLAGQHARMFY-INASGDLFLREEAIGNLNSSSLHLVATAIDSGIPPRQTSV 521
+L G F IN++ + + L L+ TA DSG PP ++V
Sbjct: 494 DTLQGAPLSSFVSINSNTGVLYALRSFDYEQFRDLKLLVTASDSGNPPLSSNV 546
Score = 64.9 bits (151), Expect = 1e-09
Identities = 66/266 (24%), Positives = 107/266 (40%), Gaps = 22/266 (8%)
Query: 57 LTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVR 116
L +LDRE+ S +++R + S +++ V D+NDN P + Y+
Sbjct: 404 LVTATSLDREQI---SEYNISLRASDGGSPPLSTETHITLHVIDINDNPPTFPHLSYSAY 460
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYAV----LPG-PHSEYLGFENELEPIIVVKK 171
+ E D D ++ + YA+ L G P S ++ N ++ +
Sbjct: 461 IPENNPRGASIFSVTAQDPDSNN-NARITYALTEDTLQGAPLSSFVSI-NSNTGVLYALR 518
Query: 172 PLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEG 231
D+E + + + D G+PPL S+ +L + VLD +D P+ Y LP D G
Sbjct: 519 SFDYEQFRDLKLLVTASDSGNPPLSSNVSLNLFVLDQNDNAPEILY----PALPTDGSTG 574
Query: 232 TFL---TTSPG----PISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIA 283
L + PG + A D+D G NA L Y L V TG+V + L+
Sbjct: 575 VELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRLLKASEPGLFSVGLHTGEVRTARALLD 634
Query: 284 ELDPSVTIVLKATQVDNPDRYALATL 309
++V+ P A TL
Sbjct: 635 RDALKQSLVVAVQDHGQPPLSATVTL 660
Score = 35.9 bits (79), Expect = 0.64
Identities = 49/211 (23%), Positives = 83/211 (39%), Gaps = 13/211 (6%)
Query: 8 SFFISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQE---KGAAVG-IVPGSKNLTLLRAL 63
S +I E+ P G+ I +++ S + IT L E +GA + V + N +L AL
Sbjct: 458 SAYIPENNPRGASIFSVTAQDPDSNNNARITYALTEDTLQGAPLSSFVSINSNTGVLYAL 517
Query: 64 DREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQ-------WEGAPYAVR 116
+ ++ + V S + +++ V D NDNAP+ +G+
Sbjct: 518 RSFDYEQFRDLKLLVTASDSGNPPLSSNVSLNLFVLDQNDNAPEILYPALPTDGSTGVEL 577
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFE 176
+ DRD G ++ L Y +L + + LD +
Sbjct: 578 APRSAEPGYLVTKVVAVDRDS-GQNAWLSYRLLKASEPGLFSVGLHTGEVRTARALLDRD 636
Query: 177 TVNNFTIKLRVQDQGSPPLYSDTTLQVTVLD 207
+ ++ + VQD G PPL + TL V V D
Sbjct: 637 ALKQ-SLVVAVQDHGQPPLSATVTLTVAVAD 666
>AY260901-1|AAP20591.1| 819|Homo sapiens cadherin-24 variant
protein.
Length = 819
Score = 89.0 bits (211), Expect = 7e-17
Identities = 104/414 (25%), Positives = 167/414 (40%), Gaps = 26/414 (6%)
Query: 9 FFISEDT--PIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDRE 66
FF+ E+ P +IG L + D E L + G I + N+ + ++LDRE
Sbjct: 51 FFVIEEYAGPEPVLIGKLHSDVDRGEGRTKYLLTGEGAGTVFVIDEATGNIHVTKSLDRE 110
Query: 67 EKIGPSNVYVNV-RCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXX 125
EK + V R R PS I ++V D+NDN P + PY V E
Sbjct: 111 EKAQYVLLAQAVDRASNRPLEPPSEFI---IKVQDINDNPPIFPLGPYHATVPEMSNVGT 167
Query: 126 XXXXXXXSDRDQP--GPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTI 183
D D P G + L Y VL G + + + + +D ET F +
Sbjct: 168 SVIQVTAHDADDPSYGNSAKLVYTVLDG--LPFFSVDPQTGVVRTAIPNMDRETQEEFLV 225
Query: 184 KLRVQDQGS--PPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPI 241
++ +D G L TT+ VT+ D +D PKF Y + + A GT + G +
Sbjct: 226 VIQAKDMGGHMGGLSGSTTVTVTLSDVNDNPPKFPQSLYQFSVVETAGPGTLV----GRL 281
Query: 242 SAADQDLGINAPLQYS-STGDHKQLIVVNKD----TGQVAATKQLIAELDPSVTIVLKAT 296
A D DLG NA + YS G+ + ++ D G + K L E S + ++AT
Sbjct: 282 RAQDPDLGDNALMAYSILDGEGSEAFSISTDLQGRDGLLTVRKPLDFESQRSYSFRVEAT 341
Query: 297 Q-VDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQ 355
+ +P FTQ Y TV E +PG+++ ++
Sbjct: 342 NTLIDPAYLRRGPFKDVASVRVAVQDAPEPPAFTQAAYHLTVPENKAPGTLVGQISAA-- 399
Query: 356 NTEFRESPLQFYVSDRSFLDK-FAIN-NAGEVILRRSLDYETTSNYFYQVMVTD 407
+ + SP+++ + S ++ F+I G + LD E + + V+ T+
Sbjct: 400 DLDSPASPIRYSILPHSDPERCFSIQPEEGTIHTAAPLDREARAWHNLTVLATE 453
Score = 50.4 bits (115), Expect = 3e-05
Identities = 67/287 (23%), Positives = 116/287 (40%), Gaps = 26/287 (9%)
Query: 167 IVVKKPLDFETVNNFTIKLRVQDQGSP-PLYSDTTLQVTVLDADDQNPKFTYEHYTALLP 225
I V K LD E + + + D+ S PL + + V D +D P F Y A +P
Sbjct: 101 IHVTKSLDREEKAQYVLLAQAVDRASNRPLEPPSEFIIKVQDINDNPPIFPLGPYHATVP 160
Query: 226 DDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQV-AATKQLIAE 284
+ + GT + A D G +A L Y+ D V+ TG V A + E
Sbjct: 161 EMSNVGTSVIQVTAH-DADDPSYGNSAKLVYTVL-DGLPFFSVDPQTGVVRTAIPNMDRE 218
Query: 285 LDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPG 344
+V++A + + +F Q Y +V E A PG
Sbjct: 219 TQEEFLVVIQAKDMGG---HMGGLSGSTTVTVTLSDVNDNPPKFPQSLYQFSVVETAGPG 275
Query: 345 SVLLTLTTVPQNTEFRESPLQFY-VSDRSFLDKFAINNA-----GEVILRRSLDYETTSN 398
+++ L Q+ + ++ L Y + D + F+I+ G + +R+ LD+E+ +
Sbjct: 276 TLVGRLRA--QDPDLGDNALMAYSILDGEGSEAFSISTDLQGRDGLLTVRKPLDFESQRS 333
Query: 399 YFYQVMVTDSISN----------DTASINISVEDVNEWEPRFRHPQY 435
Y ++V T+++ + D AS+ ++V+D E P F Y
Sbjct: 334 YSFRVEATNTLIDPAYLRRGPFKDVASVRVAVQDAPE-PPAFTQAAY 379
Score = 37.1 bits (82), Expect = 0.28
Identities = 28/116 (24%), Positives = 50/116 (43%), Gaps = 4/116 (3%)
Query: 92 IPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPG 151
+ V+++ D NDNAPQ PY V ++ DRD+ G S + + G
Sbjct: 501 VQVAIQTLDENDNAPQL-AEPYDTFVCDSAAPGQLIQVIRALDRDEVGNSSHVSFQGPLG 559
Query: 152 PHSEYLGFENE--LEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTV 205
P + + +N +++ +P + + + + D G P L S T+ V+V
Sbjct: 560 PDANFTVQDNRDGSASLLLPSRPAPPRHA-PYLVPIELWDWGQPALSSTATVTVSV 614
>AK057922-1|BAB71613.1| 493|Homo sapiens protein ( Homo sapiens
cDNA FLJ25193 fis, clone JTH00761. ).
Length = 493
Score = 89.0 bits (211), Expect = 7e-17
Identities = 104/414 (25%), Positives = 167/414 (40%), Gaps = 26/414 (6%)
Query: 9 FFISEDT--PIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDRE 66
FF+ E+ P +IG L + D E L + G I + N+ + ++LDRE
Sbjct: 51 FFVIEEYAGPEPVLIGKLHSDVDRGEGRTKYLLTGEGAGTVFVIDEATGNIHVTKSLDRE 110
Query: 67 EKIGPSNVYVNV-RCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXX 125
EK + V R R PS I ++V D+NDN P + PY V E
Sbjct: 111 EKAQYVLLAQAVDRASNRPLEPPSEFI---IKVQDINDNPPIFPLGPYHATVPEMSNVGT 167
Query: 126 XXXXXXXSDRDQP--GPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTI 183
D D P G + L Y VL G + + + + +D ET F +
Sbjct: 168 SVIQVTAHDADDPSYGNSAKLVYTVLDG--LPFFSVDPQTGVVRTAIPNMDRETQEEFLV 225
Query: 184 KLRVQDQGS--PPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPI 241
++ +D G L TT+ VT+ D +D PKF Y + + A GT + G +
Sbjct: 226 VIQAKDMGGHMGGLSGSTTVTVTLSDVNDNPPKFPQSLYQFSVVETAGPGTLV----GRL 281
Query: 242 SAADQDLGINAPLQYS-STGDHKQLIVVNKD----TGQVAATKQLIAELDPSVTIVLKAT 296
A D DLG NA + YS G+ + ++ D G + K L E S + ++AT
Sbjct: 282 RAQDPDLGDNALMAYSILDGEGSEAFSISTDLQGRDGLLTVRKPLDFESQRSYSFRVEAT 341
Query: 297 Q-VDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQ 355
+ +P FTQ Y TV E +PG+++ ++
Sbjct: 342 NTLIDPAYLRRGPFKDVASVRVAVQDAPEPPAFTQAAYHLTVPENKAPGTLVGQISAA-- 399
Query: 356 NTEFRESPLQFYVSDRSFLDK-FAIN-NAGEVILRRSLDYETTSNYFYQVMVTD 407
+ + SP+++ + S ++ F+I G + LD E + + V+ T+
Sbjct: 400 DLDSPASPIRYSILPHSDPERCFSIQPEEGTIHTAAPLDREARAWHNLTVLATE 453
Score = 50.4 bits (115), Expect = 3e-05
Identities = 67/287 (23%), Positives = 116/287 (40%), Gaps = 26/287 (9%)
Query: 167 IVVKKPLDFETVNNFTIKLRVQDQGSP-PLYSDTTLQVTVLDADDQNPKFTYEHYTALLP 225
I V K LD E + + + D+ S PL + + V D +D P F Y A +P
Sbjct: 101 IHVTKSLDREEKAQYVLLAQAVDRASNRPLEPPSEFIIKVQDINDNPPIFPLGPYHATVP 160
Query: 226 DDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQV-AATKQLIAE 284
+ + GT + A D G +A L Y+ D V+ TG V A + E
Sbjct: 161 EMSNVGTSVIQVTAH-DADDPSYGNSAKLVYTVL-DGLPFFSVDPQTGVVRTAIPNMDRE 218
Query: 285 LDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPG 344
+V++A + + +F Q Y +V E A PG
Sbjct: 219 TQEEFLVVIQAKDMGG---HMGGLSGSTTVTVTLSDVNDNPPKFPQSLYQFSVVETAGPG 275
Query: 345 SVLLTLTTVPQNTEFRESPLQFY-VSDRSFLDKFAINNA-----GEVILRRSLDYETTSN 398
+++ L Q+ + ++ L Y + D + F+I+ G + +R+ LD+E+ +
Sbjct: 276 TLVGRLRA--QDPDLGDNALMAYSILDGEGSEAFSISTDLQGRDGLLTVRKPLDFESQRS 333
Query: 399 YFYQVMVTDSISN----------DTASINISVEDVNEWEPRFRHPQY 435
Y ++V T+++ + D AS+ ++V+D E P F Y
Sbjct: 334 YSFRVEATNTLIDPAYLRRGPFKDVASVRVAVQDAPE-PPAFTQAAY 379
>AF152510-1|AAD43770.1| 829|Homo sapiens protocadherin gamma A3
short form protein protein.
Length = 829
Score = 89.0 bits (211), Expect = 7e-17
Identities = 118/533 (22%), Positives = 211/533 (39%), Gaps = 39/533 (7%)
Query: 9 FFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAA--VGIVPGSKNLTLLRALDR 65
+ +SE+ GS +G ++ + G +L + +R+ +G + P S +L +DR
Sbjct: 33 YSVSEELDKGSFVGNIANDLGLEPRELAERGVRIVSRGRTQLFSLNPQSGSLVTAERIDR 92
Query: 66 EE---KIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXX 122
EE +I V +N+ + D + V + + D+NDNAP + +++ E
Sbjct: 93 EELCAQIPLCLVKINILVE-----DKLKIFEVEIEIKDINDNAPNFPTEELEIKIGELTV 147
Query: 123 XXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLG---FENELEPIIVVKKPLDFETVN 179
D D G +S +Y + P + E P +V+++ LD E
Sbjct: 148 PGTRFPIKTAFDPDV-GINSLQNYKLSPNDYFSLAVNSVSEGAKYPELVLERALDREKKE 206
Query: 180 NFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPG 239
+ L D G P + +QV VLDA+D P FT Y + ++ GT L T
Sbjct: 207 IHQLVLVASDGGDPVHSGNLHIQVIVLDANDNPPMFTQPEYRVSVWENVPVGTRLLT--- 263
Query: 240 PISAADQDLGINAPLQY---SSTGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKAT 296
++A D D G NA + Y G ++ +N +G+V+ K L + + ++ +K
Sbjct: 264 -VNATDPDEGFNAQVSYILDKMPGKIAEIFHLNSVSGEVSILKSL--DYEDAMFYEIKIE 320
Query: 297 QVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQN 356
D P + A + + T +++V E + G + + ++
Sbjct: 321 AQDGPGLLSRAKILVTVLDVNDNAP-----EITITSLTSSVPEEGTVGREIALIDVHDRD 375
Query: 357 TEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDS----ISND 412
+ F + + F + +I+ ++ SLD E S Y + +D +S +
Sbjct: 376 SGQNGQVEVFVLGNLPFKLEKSIDQYYRLVTATSLDREQISEYNISLRASDGGSPPLSTE 435
Query: 413 TASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGDAGTLAL-- 470
T I + V D+N+ P F H Y +++ T AL
Sbjct: 436 T-HITLHVIDINDNPPTFPHLSYS-AYIPENNPRGASIFSVTAQDPDSNNNARITYALTE 493
Query: 471 -SLAGQHARMFY-INASGDLFLREEAIGNLNSSSLHLVATAIDSGIPPRQTSV 521
+L G F IN++ + + L L+ TA DSG PP ++V
Sbjct: 494 DTLQGAPLSSFVSINSNTGVLYALRSFDYEQFRDLKLLVTASDSGNPPLSSNV 546
Score = 64.9 bits (151), Expect = 1e-09
Identities = 66/266 (24%), Positives = 107/266 (40%), Gaps = 22/266 (8%)
Query: 57 LTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVR 116
L +LDRE+ S +++R + S +++ V D+NDN P + Y+
Sbjct: 404 LVTATSLDREQI---SEYNISLRASDGGSPPLSTETHITLHVIDINDNPPTFPHLSYSAY 460
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYAV----LPG-PHSEYLGFENELEPIIVVKK 171
+ E D D ++ + YA+ L G P S ++ N ++ +
Sbjct: 461 IPENNPRGASIFSVTAQDPDSNN-NARITYALTEDTLQGAPLSSFVSI-NSNTGVLYALR 518
Query: 172 PLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEG 231
D+E + + + D G+PPL S+ +L + VLD +D P+ Y LP D G
Sbjct: 519 SFDYEQFRDLKLLVTASDSGNPPLSSNVSLNLFVLDQNDNAPEILY----PALPTDGSTG 574
Query: 232 TFL---TTSPG----PISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIA 283
L + PG + A D+D G NA L Y L V TG+V + L+
Sbjct: 575 VELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRLLKASEPGLFSVGLHTGEVRTARALLD 634
Query: 284 ELDPSVTIVLKATQVDNPDRYALATL 309
++V+ P A TL
Sbjct: 635 RDALKQSLVVAVQDHGQPPLSATVTL 660
Score = 35.9 bits (79), Expect = 0.64
Identities = 49/211 (23%), Positives = 83/211 (39%), Gaps = 13/211 (6%)
Query: 8 SFFISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQE---KGAAVG-IVPGSKNLTLLRAL 63
S +I E+ P G+ I +++ S + IT L E +GA + V + N +L AL
Sbjct: 458 SAYIPENNPRGASIFSVTAQDPDSNNNARITYALTEDTLQGAPLSSFVSINSNTGVLYAL 517
Query: 64 DREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQ-------WEGAPYAVR 116
+ ++ + V S + +++ V D NDNAP+ +G+
Sbjct: 518 RSFDYEQFRDLKLLVTASDSGNPPLSSNVSLNLFVLDQNDNAPEILYPALPTDGSTGVEL 577
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFE 176
+ DRD G ++ L Y +L + + LD +
Sbjct: 578 APRSAEPGYLVTKVVAVDRDS-GQNAWLSYRLLKASEPGLFSVGLHTGEVRTARALLDRD 636
Query: 177 TVNNFTIKLRVQDQGSPPLYSDTTLQVTVLD 207
+ ++ + VQD G PPL + TL V V D
Sbjct: 637 ALKQ-SLVVAVQDHGQPPLSATVTLTVAVAD 666
>BC103928-1|AAI03929.1| 810|Homo sapiens protocadherin gamma
subfamily B, 1 protein.
Length = 810
Score = 88.6 bits (210), Expect = 9e-17
Identities = 85/359 (23%), Positives = 151/359 (42%), Gaps = 24/359 (6%)
Query: 87 DPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHY 146
+P V V V + D+NDNAP++ + + E+ D D G +S Y
Sbjct: 109 NPMNVFHVVVVIQDINDNAPRFVAKGIDLEICESALPGVKFSLDSAQDADVEG-NSLKLY 167
Query: 147 AVLPGPHSEYLGFEN---ELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQV 203
+ P + E+ P+++++KPLD E ++ + L D G PPL T + +
Sbjct: 168 TINPNQYFSLSTKESPDGSKYPVLLLEKPLDREHQSSHRLILTAMDGGDPPLSGTTHIWI 227
Query: 204 TVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYS--STGD 261
V DA+D P F+ E Y L ++ GT + + A DQD GINA + Y+ ++
Sbjct: 228 RVTDANDNAPVFSQEVYRVSLQENVPWGTSVLR----VMATDQDEGINAEITYAFLNSPI 283
Query: 262 HKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXX 321
L +N +TG + L + + + VL D A +
Sbjct: 284 STSLFNLNPNTGDITTNGTL--DFEETSRYVLSVEAKDGGVHTAHCNVQIEIVDENDNAP 341
Query: 322 XXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDR-SFLDKFAIN 380
+ T +S + E + G+V + L V + + Y + F +
Sbjct: 342 -----EVTFMSFSNQIPEDSDLGTV-IALIKVRDKDSGQNGMVTCYTQEEVPFKLESTSK 395
Query: 381 NAGEVILRRSLDYETTSNYFYQVMVTD----SISNDTASINISVEDVNEWEPRFRHPQY 435
N ++++ +L+ E T++Y ++ TD ++S+ T SI + + D+N+ P F Y
Sbjct: 396 NYYKLVIAGALNREQTADYNVTIIATDKGKPALSSRT-SITLHISDINDNAPVFHQASY 453
Score = 83.4 bits (197), Expect = 3e-15
Identities = 82/287 (28%), Positives = 131/287 (45%), Gaps = 26/287 (9%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKN---LTLLRALDREE 67
I ED+ +G++I + V S G +T QE+ + SKN L + AL+RE+
Sbjct: 352 IPEDSDLGTVIALIKVRDKDSGQNGMVTCYTQEE-VPFKLESTSKNYYKLVIAGALNREQ 410
Query: 68 KIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXX 127
NV + + D+ + S +++ + D+NDNAP + A Y V VSE
Sbjct: 411 T-ADYNVTI-IATDKGKPALSSRT-SITLHISDINDNAPVFHQASYVVHVSENNPPGASI 467
Query: 128 XXXXXSDRDQPGPHSALHYAVLPGPHS--EYLGFENELEP---IIVVKKPLDFETVNNFT 182
SD D GP+ + Y++L E L + + + P ++ ++ D E + F
Sbjct: 468 AQVSASDPDL-GPNDRVSYSILASDLEPRELLSYVS-VSPQSGVVFAQRAFDHEQLRAFE 525
Query: 183 IKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHY----TAL---LPDDAEEGTFLT 235
+ L+ +DQGSP L ++ +L+V V D +D P+ Y +AL +P AE G +T
Sbjct: 526 LTLQARDQGSPALSANVSLRVLVGDLNDNAPRVLYPALGPDGSALFDMVPRAAEPGYLVT 585
Query: 236 TSPGPISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQL 281
+ A D D G NA L Y L + TG+V + L
Sbjct: 586 ----KVVAVDADSGHNAWLSYHVLQASEPGLFSLGLRTGEVRTARAL 628
>BC103927-1|AAI03928.1| 810|Homo sapiens protocadherin gamma
subfamily B, 1 protein.
Length = 810
Score = 88.6 bits (210), Expect = 9e-17
Identities = 85/359 (23%), Positives = 151/359 (42%), Gaps = 24/359 (6%)
Query: 87 DPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHY 146
+P V V V + D+NDNAP++ + + E+ D D G +S Y
Sbjct: 109 NPMNVFHVVVVIQDINDNAPRFVAKGIDLEICESALPGVKFSLDSAQDADVEG-NSLKLY 167
Query: 147 AVLPGPHSEYLGFEN---ELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQV 203
+ P + E+ P+++++KPLD E ++ + L D G PPL T + +
Sbjct: 168 TINPNQYFSLSTKESPDGSKYPVLLLEKPLDREHQSSHRLILTAMDGGDPPLSGTTHIWI 227
Query: 204 TVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYS--STGD 261
V DA+D P F+ E Y L ++ GT + + A DQD GINA + Y+ ++
Sbjct: 228 RVTDANDNAPVFSQEVYRVSLQENVPWGTSVLR----VMATDQDEGINAEITYAFLNSPI 283
Query: 262 HKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXX 321
L +N +TG + L + + + VL D A +
Sbjct: 284 STSLFNLNPNTGDITTNGTL--DFEETSRYVLSVEAKDGGVHTAHCNVQIEIVDENDNAP 341
Query: 322 XXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDR-SFLDKFAIN 380
+ T +S + E + G+V + L V + + Y + F +
Sbjct: 342 -----EVTFMSFSNQIPEDSDLGTV-IALIKVRDKDSGQNGMVTCYTQEEVPFKLESTSK 395
Query: 381 NAGEVILRRSLDYETTSNYFYQVMVTD----SISNDTASINISVEDVNEWEPRFRHPQY 435
N ++++ +L+ E T++Y ++ TD ++S+ T SI + + D+N+ P F Y
Sbjct: 396 NYYKLVIAGALNREQTADYNVTIIATDKGKPALSSRT-SITLHISDINDNAPVFHQASY 453
Score = 83.4 bits (197), Expect = 3e-15
Identities = 82/287 (28%), Positives = 131/287 (45%), Gaps = 26/287 (9%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKN---LTLLRALDREE 67
I ED+ +G++I + V S G +T QE+ + SKN L + AL+RE+
Sbjct: 352 IPEDSDLGTVIALIKVRDKDSGQNGMVTCYTQEE-VPFKLESTSKNYYKLVIAGALNREQ 410
Query: 68 KIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXX 127
NV + + D+ + S +++ + D+NDNAP + A Y V VSE
Sbjct: 411 T-ADYNVTI-IATDKGKPALSSRT-SITLHISDINDNAPVFHQASYVVHVSENNPPGASI 467
Query: 128 XXXXXSDRDQPGPHSALHYAVLPGPHS--EYLGFENELEP---IIVVKKPLDFETVNNFT 182
SD D GP+ + Y++L E L + + + P ++ ++ D E + F
Sbjct: 468 AQVSASDPDL-GPNGRVSYSILASDLEPRELLSYVS-VSPQSGVVFAQRAFDHEQLRAFE 525
Query: 183 IKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHY----TAL---LPDDAEEGTFLT 235
+ L+ +DQGSP L ++ +L+V V D +D P+ Y +AL +P AE G +T
Sbjct: 526 LTLQARDQGSPALSANVSLRVLVGDLNDNAPRVLYPALGPDGSALFDMVPRAAEPGYLVT 585
Query: 236 TSPGPISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQL 281
+ A D D G NA L Y L + TG+V + L
Sbjct: 586 ----KVVAVDADSGHNAWLSYHVLQASEPGLFSLGLRTGEVRTARAL 628
>BC103926-1|AAI03927.1| 810|Homo sapiens protocadherin gamma
subfamily B, 1 protein.
Length = 810
Score = 88.6 bits (210), Expect = 9e-17
Identities = 85/359 (23%), Positives = 151/359 (42%), Gaps = 24/359 (6%)
Query: 87 DPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHY 146
+P V V V + D+NDNAP++ + + E+ D D G +S Y
Sbjct: 109 NPMNVFHVVVVIQDINDNAPRFVAKGIDLEICESALPGVKFSLDSAQDADVEG-NSLKLY 167
Query: 147 AVLPGPHSEYLGFEN---ELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQV 203
+ P + E+ P+++++KPLD E ++ + L D G PPL T + +
Sbjct: 168 TINPNQYFSLSTKESPDGSKYPVLLLEKPLDREHQSSHRLILTAMDGGDPPLSGTTHIWI 227
Query: 204 TVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYS--STGD 261
V DA+D P F+ E Y L ++ GT + + A DQD GINA + Y+ ++
Sbjct: 228 RVTDANDNAPVFSQEVYRVSLQENVPWGTSVLR----VMATDQDEGINAEITYAFLNSPI 283
Query: 262 HKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXX 321
L +N +TG + L + + + VL D A +
Sbjct: 284 STSLFNLNPNTGDITTNGTL--DFEETSRYVLSVEAKDGGVHTAHCNVQIEIVDENDNAP 341
Query: 322 XXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDR-SFLDKFAIN 380
+ T +S + E + G+V + L V + + Y + F +
Sbjct: 342 -----EVTFMSFSNQIPEDSDLGTV-IALIKVRDKDSGQNGMVTCYTQEEVPFKLESTSK 395
Query: 381 NAGEVILRRSLDYETTSNYFYQVMVTD----SISNDTASINISVEDVNEWEPRFRHPQY 435
N ++++ +L+ E T++Y ++ TD ++S+ T SI + + D+N+ P F Y
Sbjct: 396 NYYKLVIAGALNREQTADYNVTIIATDKGKPALSSRT-SITLHISDINDNAPVFHQASY 453
Score = 83.4 bits (197), Expect = 3e-15
Identities = 82/287 (28%), Positives = 131/287 (45%), Gaps = 26/287 (9%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKN---LTLLRALDREE 67
I ED+ +G++I + V S G +T QE+ + SKN L + AL+RE+
Sbjct: 352 IPEDSDLGTVIALIKVRDKDSGQNGMVTCYTQEE-VPFKLESTSKNYYKLVIAGALNREQ 410
Query: 68 KIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXX 127
NV + + D+ + S +++ + D+NDNAP + A Y V VSE
Sbjct: 411 T-ADYNVTI-IATDKGKPALSSRT-SITLHISDINDNAPVFHQASYVVHVSENNPPGASI 467
Query: 128 XXXXXSDRDQPGPHSALHYAVLPGPHS--EYLGFENELEP---IIVVKKPLDFETVNNFT 182
SD D GP+ + Y++L E L + + + P ++ ++ D E + F
Sbjct: 468 AQVSASDPDL-GPNGRVSYSILASDLEPRELLSYVS-VSPQSGVVFAQRAFDHEQLRAFE 525
Query: 183 IKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHY----TAL---LPDDAEEGTFLT 235
+ L+ +DQGSP L ++ +L+V V D +D P+ Y +AL +P AE G +T
Sbjct: 526 LTLQARDQGSPALSANVSLRVLVGDLNDNAPRVLYPALGPDGSALFDMVPRAAEPGYLVT 585
Query: 236 TSPGPISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQL 281
+ A D D G NA L Y L + TG+V + L
Sbjct: 586 ----KVVAVDADSGHNAWLSYHVLQASEPGLFSLGLRTGEVRTARAL 628
>BC069064-1|AAH69064.1| 824|Homo sapiens PCDHA3 protein protein.
Length = 824
Score = 88.6 bits (210), Expect = 9e-17
Identities = 113/449 (25%), Positives = 187/449 (41%), Gaps = 43/449 (9%)
Query: 9 FFISEDTPIGSIIGTLSVNGDPSEDLGDITLRL-----QEKGAAVGIVPGSKNLTLLRAL 63
+ +SE+ G+ +G ++ D +L ++ RL + G + + + L + +
Sbjct: 33 YSVSEEAKHGTFVGRIAQ--DLGLELAELVPRLFRVASKRHGDLLEVNLQNGILFVNSRI 90
Query: 64 DREEKIGPS---NVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSET 120
DREE G S ++++ V DR P V V V V D+NDNAP + A + +SE+
Sbjct: 91 DREELCGRSAECSIHLEVIVDR-----PLQVFHVEVEVKDINDNAPVFPMAVKNLFISES 145
Query: 121 XXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFE-----NELEPI-IVVKKPLD 174
SD D G +S L Y++ +EY + E++ + +V+KK L+
Sbjct: 146 RQPGSRFSLEGASDADI-GTNSLLTYSL---DSTEYFTLDVKRNDEEIKSLGLVLKKNLN 201
Query: 175 FETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFL 234
E + + D G P L T L++TVLD +D P F Y L ++A GT +
Sbjct: 202 REDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAPAFERTIYKVRLLENAPNGTLV 261
Query: 235 TTSPGPISAADQDLGINAPLQYSSTGDHKQLIV----VNKDTGQVAATKQLIAELDPSVT 290
T ++A D D G+N + YS D I+ ++ GQ++ + E S
Sbjct: 262 VT----VNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNGQISVKGNIDFEESKSYE 317
Query: 291 IVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTL 350
+ ++AT NP T+ + + S V E SP S ++ L
Sbjct: 318 VQVEATDKGNPPMSDHCTVLLEIVDINDNVP-----ELVIQSLSLPVLED-SPLSTVIAL 371
Query: 351 TTVPQNTEFRESPLQFYVSDR-SFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSI 409
+V + ++ F N ++L LD E+ S Y V D
Sbjct: 372 ISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSAYELVVTARDGG 431
Query: 410 SND---TASINISVEDVNEWEPRFRHPQY 435
S TA +++ V DVN+ P F +Y
Sbjct: 432 SPSLWATAIVSVEVADVNDNAPAFSQSEY 460
Score = 82.2 bits (194), Expect = 7e-15
Identities = 79/353 (22%), Positives = 153/353 (43%), Gaps = 23/353 (6%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
+ + V DVNDNAP +E Y VR+ E +D D+ G + + Y+
Sbjct: 228 LKITVLDVNDNAPAFERTIYKVRLLENAPNGTLVVTVNATDLDE-GVNKDIAYSFNTDMS 286
Query: 154 SEYLGFENELEPI---IVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADD 210
++ L + L+P+ I VK +DFE ++ +++ D+G+PP+ T+ + ++D +D
Sbjct: 287 ADILS-KFHLDPVNGQISVKGNIDFEESKSYEVQVEATDKGNPPMSDHCTVLLEIVDIND 345
Query: 211 QNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHK-QLIVVN 269
P+ + + + +D+ L+T IS +D+D G+N + S T +L+
Sbjct: 346 NVPELVIQSLSLPVLEDSP----LSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTF 401
Query: 270 KDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFT 329
K+ + L E + +V+ A +P +A A + F+
Sbjct: 402 KNYYSLVLDSPLDRESVSAYELVVTARDGGSPSLWATAIVSVEVADVNDNAPA-----FS 456
Query: 330 QKQYSTTVSEGASPGSVLLTLTT----VPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGE 384
Q +Y+ V E PG + T++ +N S ++ V +R+ +++ +G+
Sbjct: 457 QSEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSLVERRVGERALSSYVSVHAESGK 516
Query: 385 VILRRSLDYETTSNYFYQVMVTDS---ISNDTASINISVEDVNEWEPRFRHPQ 434
V + LD+E +QV D+ ++ + V D N+ P P+
Sbjct: 517 VYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLMPR 569
Score = 72.1 bits (169), Expect = 8e-12
Identities = 85/316 (26%), Positives = 126/316 (39%), Gaps = 26/316 (8%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKN---LTLLRALDREE 67
+ ED+P+ ++I +SV+ S G +T L +V KN L L LDRE
Sbjct: 359 VLEDSPLSTVIALISVSDRDSGVNGQVTCSLTPH-VPFKLVSTFKNYYSLVLDSPLDRES 417
Query: 68 KIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXX 127
+ + V R + + + VSV V DVNDNAP + + Y V V E
Sbjct: 418 -VSAYELVVTARDGGSPSLWATAI--VSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHI 474
Query: 128 XXXXXSDRDQPG----PHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTI 183
D D +S + V S Y+ E + ++ PLD E +
Sbjct: 475 FTVSARDADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQ-PLDHEELELLQF 533
Query: 184 KLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEH-------YTALLPDDAEEGTFLTT 236
++ +D G PPL S+ TLQV VLD +D P + L+P G +
Sbjct: 534 QVSARDAGVPPLGSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVV-- 591
Query: 237 SPGPISAADQDLGINAPLQYS---STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVL 293
+ A D D G NA L Y TG + V TG+++ T+ L P +++
Sbjct: 592 --AKVRAVDADSGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLV 649
Query: 294 KATQVDNPDRYALATL 309
P A AT+
Sbjct: 650 LVKDHGEPSLTATATV 665
>AL834258-1|CAD38933.1| 1084|Homo sapiens hypothetical protein
protein.
Length = 1084
Score = 88.6 bits (210), Expect = 9e-17
Identities = 91/376 (24%), Positives = 144/376 (38%), Gaps = 26/376 (6%)
Query: 160 ENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEH 219
E E P ++V++ LD E + + +K++V+D G+P S LQVTV D +D P F
Sbjct: 44 EGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQ 103
Query: 220 YTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQY----SSTGDHKQLIVVNKDTGQV 275
+P++A G TS + A D D+G NA ++Y K+L +N TG +
Sbjct: 104 VEVHIPENAPVG----TSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALNNTTGLI 159
Query: 276 AATKQLIAELDPSVTIVLKATQV--DNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQY 333
+ LD T + K T + D A AT+
Sbjct: 160 TVQR----SLDREETAIHKVTVLASDGSSTPARATVTINVTDVNDNPPNIDLRYIISPIN 215
Query: 334 STTVSEGASPGSVLLTLTTV-PQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLD 392
T P + + L TV ++T+ + F + F K +N + LD
Sbjct: 216 GTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYLLETSSLLD 275
Query: 393 YETTSNYFYQVMVTDS---ISNDTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXX 449
YE T + ++++ +DS N TA + + +ED N+ P F P E
Sbjct: 276 YEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYL 335
Query: 450 XXXXXXXXXVAHDGDAGTLA--LSLAGQHARMFYINASGDLFLREEAIGNLNSSSLHLVA 507
A D D+G A + G +A F ++ +
Sbjct: 336 TTIS------ATDEDSGKNADIVYQLGPNASFFDLDRKTGVLTASRVFDREEQERFIFTV 389
Query: 508 TAIDSGIPPRQTSVPV 523
TA D+G PP Q+ V
Sbjct: 390 TARDNGTPPLQSQAAV 405
Score = 79.8 bits (188), Expect = 4e-14
Identities = 67/298 (22%), Positives = 122/298 (40%), Gaps = 10/298 (3%)
Query: 10 FISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEKI 69
++SE P+ + I ++V+ D D+ + E+ + N LL +
Sbjct: 219 YLSEKDPVNTKIALITVS-DKDTDVNGKVICFIEREVPFHLKAVYDNQYLLETSSLLDYE 277
Query: 70 GPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXX 129
G + + V V++ D NDN P + + VSE
Sbjct: 278 GTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTT 337
Query: 130 XXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQD 189
+D D G ++ + Y + GP++ + + + ++ + D E F + +D
Sbjct: 338 ISATDEDS-GKNADIVYQL--GPNASFFDLDRKTG-VLTASRVFDREEQERFIFTVTARD 393
Query: 190 QGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLG 249
G+PPL S + VTVLD +D +PKFT+ H+ + ++ + ++ G I+ D D G
Sbjct: 394 NGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPK----YSTVGVITVTDADAG 449
Query: 250 INAPLQYSSTGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALA 307
N + S D+ V++ +G + + E S T +KAT P R + A
Sbjct: 450 ENKAVTLSILNDNDN-FVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTA 506
Score = 63.3 bits (147), Expect = 4e-09
Identities = 65/269 (24%), Positives = 110/269 (40%), Gaps = 15/269 (5%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEKIG 70
+SE+ G + T+S + S DI +L + + + LT R DREE+
Sbjct: 325 VSENNRRGLYLTTISATDEDSGKNADIVYQLGPNASFFDLDRKTGVLTASRVFDREEQ-- 382
Query: 71 PSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXX 130
V T V V V D NDN+P++ + VSE
Sbjct: 383 -ERFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVI 441
Query: 131 XXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQ 190
+D D G + A+ ++L + L + +I D E +++T ++ D
Sbjct: 442 TVTDADA-GENKAVTLSILNDNDNFVL---DPYSGVIKSNVSFDREQQSSYTFDVKATDG 497
Query: 191 GSPPLYSDTTLQVTVLDADDQNPKFTYEHYTA---LLPDDAEEGTFLTTSPGPISAADQD 247
G PP S + + V+D +D +P L+P A G+ + + A D D
Sbjct: 498 GQPPRSSTAKVTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPGSVV----AEVFAVDVD 553
Query: 248 LGINAPLQYS-STGDHKQLIVVNKDTGQV 275
G+NA L+Y+ +G++K L ++ TG +
Sbjct: 554 TGMNAELKYTIVSGNNKGLFRIDPVTGNI 582
Score = 55.2 bits (127), Expect = 1e-06
Identities = 94/477 (19%), Positives = 167/477 (35%), Gaps = 27/477 (5%)
Query: 57 LTLLRALDREEKIGPSNVYV-NVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAV 115
L + + LDRE+K + YV ++ + T S + V V DVNDN P ++ V
Sbjct: 51 LIVQQNLDREQK----DTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEV 106
Query: 116 RVSETXXXXXXXXXXXXSDRDQPGPHSALHY--AVLPGPHSEYLGFENELEPIIVVKKPL 173
+ E +D D G ++ + Y P ++ L N +I V++ L
Sbjct: 107 HIPENAPVGTSVIQLHATDAD-IGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQRSL 165
Query: 174 DFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDA--EEG 231
D E + + D S P + T+ VT D +D P + + + E
Sbjct: 166 DREETAIHKVTVLASDGSSTPARATVTINVT--DVNDNPPNIDLRYIISPINGTVYLSEK 223
Query: 232 TFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLI-AELDPSVT 290
+ T I+ +D+D +N + + + D + T L+ E +
Sbjct: 224 DPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYLLETSSLLDYEGTKEFS 283
Query: 291 IVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTL 350
+ A+ P A + F Q +VSE G L T+
Sbjct: 284 FKIVASDSGKPSLNQTALVRVKLEDENDNPPI-----FNQPVIELSVSENNRRGLYLTTI 338
Query: 351 TTVPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSIS 410
+ +++ + + SF D G + R D E + + V D+ +
Sbjct: 339 SATDEDSGKNADIVYQLGPNASFFD--LDRKTGVLTASRVFDREEQERFIFTVTARDNGT 396
Query: 411 ---NDTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGDAGT 467
A++ ++V D N+ P+F H ++F A G+
Sbjct: 397 PPLQSQAAVIVTVLDENDNSPKFTHNHFQF---FVSENLPKYSTVGVITVTDADAGENKA 453
Query: 468 LALSLAGQHARMFYINASGDLFLREEAIGNLNSSSLHLVATAIDSGIPPRQTSVPVT 524
+ LS+ + F ++ + + SS A D G PPR ++ VT
Sbjct: 454 VTLSILNDNDN-FVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVT 509
Score = 35.9 bits (79), Expect = 0.64
Identities = 26/98 (26%), Positives = 46/98 (46%), Gaps = 3/98 (3%)
Query: 9 FFISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEK 68
FF+SE+ P S +G ++V + + +TL + + P S + + DRE++
Sbjct: 426 FFVSENLPKYSTVGVITVTDADAGENKAVTLSILNDNDNFVLDPYSGVIKSNVSFDREQQ 485
Query: 69 IGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAP 106
S+ +V+ S V++ V DVNDN+P
Sbjct: 486 ---SSYTFDVKATDGGQPPRSSTAKVTINVMDVNDNSP 520
>AF152517-1|AAD43777.1| 810|Homo sapiens protocadherin gamma B1
short form protein protein.
Length = 810
Score = 88.6 bits (210), Expect = 9e-17
Identities = 85/359 (23%), Positives = 151/359 (42%), Gaps = 24/359 (6%)
Query: 87 DPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHY 146
+P V V V + D+NDNAP++ + + E+ D D G +S Y
Sbjct: 109 NPMNVFHVVVVIQDINDNAPRFVAKGIDLEICESALPGVKFSLDSAQDADVEG-NSLKLY 167
Query: 147 AVLPGPHSEYLGFEN---ELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQV 203
+ P + E+ P+++++KPLD E ++ + L D G PPL T + +
Sbjct: 168 TINPNQYFSLSTKESPDGSKYPVLLLEKPLDREHQSSHRLILTAMDGGDPPLSGTTHIWI 227
Query: 204 TVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYS--STGD 261
V DA+D P F+ E Y L ++ GT + + A DQD GINA + Y+ ++
Sbjct: 228 RVTDANDNAPVFSQEVYRVSLQENVPWGTSVLR----VMATDQDEGINAEITYAFLNSPI 283
Query: 262 HKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXX 321
L +N +TG + L + + + VL D A +
Sbjct: 284 STSLFNLNPNTGDITTNGTL--DFEETSRYVLSVEAKDGGVHTAHCNVQIEIVDENDNAP 341
Query: 322 XXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDR-SFLDKFAIN 380
+ T +S + E + G+V + L V + + Y + F +
Sbjct: 342 -----EVTFMSFSNQIPEDSDLGTV-IALIKVRDKDSGQNGMVTCYTQEEVPFKLESTSK 395
Query: 381 NAGEVILRRSLDYETTSNYFYQVMVTD----SISNDTASINISVEDVNEWEPRFRHPQY 435
N ++++ +L+ E T++Y ++ TD ++S+ T SI + + D+N+ P F Y
Sbjct: 396 NYYKLVIAGALNREQTADYNVTIIATDKGKPALSSRT-SITLHISDINDNAPVFHQASY 453
Score = 83.4 bits (197), Expect = 3e-15
Identities = 82/287 (28%), Positives = 131/287 (45%), Gaps = 26/287 (9%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKN---LTLLRALDREE 67
I ED+ +G++I + V S G +T QE+ + SKN L + AL+RE+
Sbjct: 352 IPEDSDLGTVIALIKVRDKDSGQNGMVTCYTQEE-VPFKLESTSKNYYKLVIAGALNREQ 410
Query: 68 KIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXX 127
NV + + D+ + S +++ + D+NDNAP + A Y V VSE
Sbjct: 411 T-ADYNVTI-IATDKGKPALSSRT-SITLHISDINDNAPVFHQASYVVHVSENNPPGASI 467
Query: 128 XXXXXSDRDQPGPHSALHYAVLPGPHS--EYLGFENELEP---IIVVKKPLDFETVNNFT 182
SD D GP+ + Y++L E L + + + P ++ ++ D E + F
Sbjct: 468 AQVSASDPDL-GPNGRVSYSILASDLEPRELLSYVS-VSPQSGVVFAQRAFDHEQLRAFE 525
Query: 183 IKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHY----TAL---LPDDAEEGTFLT 235
+ L+ +DQGSP L ++ +L+V V D +D P+ Y +AL +P AE G +T
Sbjct: 526 LTLQARDQGSPALSANVSLRVLVGDLNDNAPRVLYPALGPDGSALFDMVPRAAEPGYLVT 585
Query: 236 TSPGPISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQL 281
+ A D D G NA L Y L + TG+V + L
Sbjct: 586 ----KVVAVDADSGHNAWLSYHVLQASEPGLFSLGLRTGEVRTARAL 628
>AF152330-1|AAD43724.1| 927|Homo sapiens protocadherin gamma B1
protein.
Length = 927
Score = 88.6 bits (210), Expect = 9e-17
Identities = 85/359 (23%), Positives = 151/359 (42%), Gaps = 24/359 (6%)
Query: 87 DPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHY 146
+P V V V + D+NDNAP++ + + E+ D D G +S Y
Sbjct: 109 NPMNVFHVVVVIQDINDNAPRFVAKGIDLEICESALPGVKFSLDSAQDADVEG-NSLKLY 167
Query: 147 AVLPGPHSEYLGFEN---ELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQV 203
+ P + E+ P+++++KPLD E ++ + L D G PPL T + +
Sbjct: 168 TINPNQYFSLSTKESPDGSKYPVLLLEKPLDREHQSSHRLILTAMDGGDPPLSGTTHIWI 227
Query: 204 TVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYS--STGD 261
V DA+D P F+ E Y L ++ GT + + A DQD GINA + Y+ ++
Sbjct: 228 RVTDANDNAPVFSQEVYRVSLQENVPWGTSVLR----VMATDQDEGINAEITYAFLNSPI 283
Query: 262 HKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXX 321
L +N +TG + L + + + VL D A +
Sbjct: 284 STSLFNLNPNTGDITTNGTL--DFEETSRYVLSVEAKDGGVHTAHCNVQIEIVDENDNAP 341
Query: 322 XXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDR-SFLDKFAIN 380
+ T +S + E + G+V + L V + + Y + F +
Sbjct: 342 -----EVTFMSFSNQIPEDSDLGTV-IALIKVRDKDSGQNGMVTCYTQEEVPFKLESTSK 395
Query: 381 NAGEVILRRSLDYETTSNYFYQVMVTD----SISNDTASINISVEDVNEWEPRFRHPQY 435
N ++++ +L+ E T++Y ++ TD ++S+ T SI + + D+N+ P F Y
Sbjct: 396 NYYKLVIAGALNREQTADYNVTIIATDKGKPALSSRT-SITLHISDINDNAPVFHQASY 453
Score = 83.4 bits (197), Expect = 3e-15
Identities = 82/287 (28%), Positives = 131/287 (45%), Gaps = 26/287 (9%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKN---LTLLRALDREE 67
I ED+ +G++I + V S G +T QE+ + SKN L + AL+RE+
Sbjct: 352 IPEDSDLGTVIALIKVRDKDSGQNGMVTCYTQEE-VPFKLESTSKNYYKLVIAGALNREQ 410
Query: 68 KIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXX 127
NV + + D+ + S +++ + D+NDNAP + A Y V VSE
Sbjct: 411 T-ADYNVTI-IATDKGKPALSSRT-SITLHISDINDNAPVFHQASYVVHVSENNPPGASI 467
Query: 128 XXXXXSDRDQPGPHSALHYAVLPGPHS--EYLGFENELEP---IIVVKKPLDFETVNNFT 182
SD D GP+ + Y++L E L + + + P ++ ++ D E + F
Sbjct: 468 AQVSASDPDL-GPNGRVSYSILASDLEPRELLSYVS-VSPQSGVVFAQRAFDHEQLRAFE 525
Query: 183 IKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHY----TAL---LPDDAEEGTFLT 235
+ L+ +DQGSP L ++ +L+V V D +D P+ Y +AL +P AE G +T
Sbjct: 526 LTLQARDQGSPALSANVSLRVLVGDLNDNAPRVLYPALGPDGSALFDMVPRAAEPGYLVT 585
Query: 236 TSPGPISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQL 281
+ A D D G NA L Y L + TG+V + L
Sbjct: 586 ----KVVAVDADSGHNAWLSYHVLQASEPGLFSLGLRTGEVRTARAL 628
>BC033735-1|AAH33735.1| 890|Homo sapiens PCDHA5 protein protein.
Length = 890
Score = 87.8 bits (208), Expect = 2e-16
Identities = 106/443 (23%), Positives = 176/443 (39%), Gaps = 31/443 (6%)
Query: 9 FFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAAVGIVPGSKN--LTLLRALDR 65
+ I E+ G+ +G ++ + G +L R+ KG + +N L + +DR
Sbjct: 32 YSIPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKGRGDLLEVNLQNGILFVNSRIDR 91
Query: 66 EE---KIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXX 122
EE + ++++ V DR P V V V V D+NDN P++ + + E+
Sbjct: 92 EELCRRRAECSIHLEVIVDR-----PLQVFHVEVAVKDINDNPPRFSRQEQRLFILESRM 146
Query: 123 XXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPI---IVVKKPLDFETVN 179
SD D G ++ L Y + P + + NE E +V++K LD E
Sbjct: 147 PDSRFPLEGASDLDI-GANAQLRYRLNPNEYFDLDVKTNEEETNFLELVLRKSLDREETQ 205
Query: 180 NFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPG 239
+ + D G P L L + VLDA+D P+F Y L ++A GT +
Sbjct: 206 EHRLLVIATDGGKPELTGTVQLLINVLDANDSAPEFDKSIYNVRLLENAPSGTLVI---- 261
Query: 240 PISAADQDLGINAPLQYSSTG----DHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKA 295
++A+D D GIN + Y + D K ++N +TG++ +L E S I
Sbjct: 262 KLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGEIKVNGELDYEDYNSYEI---- 317
Query: 296 TQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQ 355
+D D+ + V E A +V+ ++ +
Sbjct: 318 -NIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVKEDAPLSTVIALISVSDR 376
Query: 356 NTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSISND--- 412
++ + F N ++L +LD E+ S Y V D S
Sbjct: 377 DSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSVYELVVTARDGGSPSLWA 436
Query: 413 TASINISVEDVNEWEPRFRHPQY 435
TAS+++ V DVN+ P F PQY
Sbjct: 437 TASVSVEVADVNDNAPAFAQPQY 459
Score = 78.2 bits (184), Expect = 1e-13
Identities = 92/318 (28%), Positives = 127/318 (39%), Gaps = 30/318 (9%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKN---LTLLRALDREE 67
+ ED P+ ++I +SV+ S G +T L +V KN L L ALDRE
Sbjct: 358 VKEDAPLSTVIALISVSDRDSGANGQVTCSLMPH-VPFKLVSTFKNYYSLVLDSALDRES 416
Query: 68 KIGPSNVYVNVRCDRRRTTDPSF--VIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXX 125
+VY V R PS VSV V DVNDNAP + Y V V E
Sbjct: 417 V----SVYELV-VTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGC 471
Query: 126 XXXXXXXSDRDQPG----PHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNF 181
D D +S + V P S Y+ E + ++ PLD E V
Sbjct: 472 HIFTVSARDADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQ-PLDHEEVELL 530
Query: 182 TIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKF-------TYEHYTALLPDDAEEGTFL 234
++ +D G PPL S+ TLQV VLD +D P T + L+P G +
Sbjct: 531 QFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVV 590
Query: 235 TTSPGPISAADQDLGINAPLQYS---STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTI 291
+ A D D G NA L Y + G + V TG+++ T+ L P +
Sbjct: 591 ----AKVRAVDPDSGYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRL 646
Query: 292 VLKATQVDNPDRYALATL 309
++ P A AT+
Sbjct: 647 LVLVKDHGEPPLTATATV 664
Score = 72.1 bits (169), Expect = 8e-12
Identities = 89/390 (22%), Positives = 157/390 (40%), Gaps = 26/390 (6%)
Query: 57 LTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVR 116
L L ++LDREE + + + T + + + V D ND+AP+++ + Y VR
Sbjct: 193 LVLRKSLDREETQEHRLLVIATDGGKPELTG---TVQLLINVLDANDSAPEFDKSIYNVR 249
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHY---AVLPGPHSEYLGFENELEPIIVVKKPL 173
+ E SD D+ +++ VL S+++ N E I V L
Sbjct: 250 LLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGE--IKVNGEL 307
Query: 174 DFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTF 233
D+E N++ I + D+ + PL + V +LD +D P+ T LP +E
Sbjct: 308 DYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAIT--TLFLP--VKEDAP 363
Query: 234 LTTSPGPISAADQDLGINAPLQYSSTGDHK-QLIVVNKDTGQVAATKQLIAELDPSVTIV 292
L+T IS +D+D G N + S +L+ K+ + L E +V
Sbjct: 364 LSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSVYELV 423
Query: 293 LKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTT 352
+ A +P +A A++ F Q QY+ V E PG + T++
Sbjct: 424 VTARDGGSPSLWATASVSVEVADVNDNAPA-----FAQPQYTVFVKENNPPGCHIFTVSA 478
Query: 353 ----VPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTD 407
+N S ++ V +R +++ +G+V + LD+E +QV D
Sbjct: 479 RDADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARD 538
Query: 408 S---ISNDTASINISVEDVNEWEPRFRHPQ 434
+ ++ + V D N+ P P+
Sbjct: 539 AGVPPLGSNVTLQVFVLDENDNAPALLVPR 568
Score = 32.7 bits (71), Expect = 6.0
Identities = 52/222 (23%), Positives = 88/222 (39%), Gaps = 24/222 (10%)
Query: 10 FISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEK-------GAAVGIVPGSKNLTLLRA 62
F+ E+ P G I T+S +++ ++ L E+ + V + S + L+
Sbjct: 462 FVKENNPPGCHIFTVSARDADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQP 521
Query: 63 LDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVW--DVNDNAPQW-------EGAPY 113
LD EE + + R P V+++V+ D NDNAP G
Sbjct: 522 LDHEEV-----ELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAV 576
Query: 114 AVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEP-IIVVKKP 172
+ V + D D G ++ L Y + P P S + F L I +
Sbjct: 577 SELVPRSVGAGHVVAKVRAVDPDS-GYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRS 635
Query: 173 LDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPK 214
LD + + V+D G PPL + T+ V+++++ Q PK
Sbjct: 636 LDETEAPRHRLLVLVKDHGEPPLTATATVLVSLVES-GQAPK 676
>AF152483-1|AAD43744.1| 816|Homo sapiens protocadherin alpha 5
short form protein protein.
Length = 816
Score = 87.8 bits (208), Expect = 2e-16
Identities = 106/443 (23%), Positives = 176/443 (39%), Gaps = 31/443 (6%)
Query: 9 FFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAAVGIVPGSKN--LTLLRALDR 65
+ I E+ G+ +G ++ + G +L R+ KG + +N L + +DR
Sbjct: 32 YSIPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKGRGDLLEVNLQNGILFVNSRIDR 91
Query: 66 EE---KIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXX 122
EE + ++++ V DR P V V V V D+NDN P++ + + E+
Sbjct: 92 EELCRRRAECSIHLEVIVDR-----PLQVFHVEVAVKDINDNPPRFSRQEQRLFILESRM 146
Query: 123 XXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPI---IVVKKPLDFETVN 179
SD D G ++ L Y + P + + NE E +V++K LD E
Sbjct: 147 PDSRFPLEGASDLDI-GANAQLRYRLNPNEYFDLDVKTNEEETNFLELVLRKSLDREETQ 205
Query: 180 NFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPG 239
+ + D G P L L + VLDA+D P+F Y L ++A GT +
Sbjct: 206 EHRLLVIATDGGKPELTGTVQLLINVLDANDNAPEFDKSIYNVRLLENAPSGTLVI---- 261
Query: 240 PISAADQDLGINAPLQYSSTG----DHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKA 295
++A+D D GIN + Y + D K ++N +TG++ +L E S I
Sbjct: 262 KLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGEIKVNGELDYEDYNSYEI---- 317
Query: 296 TQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQ 355
+D D+ + V E A +V+ ++ +
Sbjct: 318 -NIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVKEDAPLSTVIALISVSDR 376
Query: 356 NTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSISND--- 412
++ + F N ++L +LD E+ S Y V D S
Sbjct: 377 DSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSVYELVVTARDGGSPSLWA 436
Query: 413 TASINISVEDVNEWEPRFRHPQY 435
TAS+++ V DVN+ P F PQY
Sbjct: 437 TASVSVEVADVNDNAPAFAQPQY 459
Score = 78.2 bits (184), Expect = 1e-13
Identities = 92/318 (28%), Positives = 127/318 (39%), Gaps = 30/318 (9%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKN---LTLLRALDREE 67
+ ED P+ ++I +SV+ S G +T L +V KN L L ALDRE
Sbjct: 358 VKEDAPLSTVIALISVSDRDSGANGQVTCSLMPH-VPFKLVSTFKNYYSLVLDSALDRES 416
Query: 68 KIGPSNVYVNVRCDRRRTTDPSF--VIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXX 125
+VY V R PS VSV V DVNDNAP + Y V V E
Sbjct: 417 V----SVYELV-VTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGC 471
Query: 126 XXXXXXXSDRDQPG----PHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNF 181
D D +S + V P S Y+ E + ++ PLD E V
Sbjct: 472 HIFTVSARDADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQ-PLDHEEVELL 530
Query: 182 TIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKF-------TYEHYTALLPDDAEEGTFL 234
++ +D G PPL S+ TLQV VLD +D P T + L+P G +
Sbjct: 531 QFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVV 590
Query: 235 TTSPGPISAADQDLGINAPLQYS---STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTI 291
+ A D D G NA L Y + G + V TG+++ T+ L P +
Sbjct: 591 ----AKVRAVDPDSGYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRL 646
Query: 292 VLKATQVDNPDRYALATL 309
++ P A AT+
Sbjct: 647 LVLVKDHGEPPLTATATV 664
Score = 74.1 bits (174), Expect = 2e-12
Identities = 90/390 (23%), Positives = 157/390 (40%), Gaps = 26/390 (6%)
Query: 57 LTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVR 116
L L ++LDREE + + + T + + + V D NDNAP+++ + Y VR
Sbjct: 193 LVLRKSLDREETQEHRLLVIATDGGKPELTG---TVQLLINVLDANDNAPEFDKSIYNVR 249
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHY---AVLPGPHSEYLGFENELEPIIVVKKPL 173
+ E SD D+ +++ VL S+++ N E I V L
Sbjct: 250 LLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGE--IKVNGEL 307
Query: 174 DFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTF 233
D+E N++ I + D+ + PL + V +LD +D P+ T LP +E
Sbjct: 308 DYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAIT--TLFLP--VKEDAP 363
Query: 234 LTTSPGPISAADQDLGINAPLQYSSTGDHK-QLIVVNKDTGQVAATKQLIAELDPSVTIV 292
L+T IS +D+D G N + S +L+ K+ + L E +V
Sbjct: 364 LSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSVYELV 423
Query: 293 LKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTT 352
+ A +P +A A++ F Q QY+ V E PG + T++
Sbjct: 424 VTARDGGSPSLWATASVSVEVADVNDNAPA-----FAQPQYTVFVKENNPPGCHIFTVSA 478
Query: 353 ----VPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTD 407
+N S ++ V +R +++ +G+V + LD+E +QV D
Sbjct: 479 RDADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARD 538
Query: 408 S---ISNDTASINISVEDVNEWEPRFRHPQ 434
+ ++ + V D N+ P P+
Sbjct: 539 AGVPPLGSNVTLQVFVLDENDNAPALLVPR 568
Score = 32.7 bits (71), Expect = 6.0
Identities = 52/222 (23%), Positives = 88/222 (39%), Gaps = 24/222 (10%)
Query: 10 FISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEK-------GAAVGIVPGSKNLTLLRA 62
F+ E+ P G I T+S +++ ++ L E+ + V + S + L+
Sbjct: 462 FVKENNPPGCHIFTVSARDADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQP 521
Query: 63 LDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVW--DVNDNAPQW-------EGAPY 113
LD EE + + R P V+++V+ D NDNAP G
Sbjct: 522 LDHEEV-----ELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAV 576
Query: 114 AVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEP-IIVVKKP 172
+ V + D D G ++ L Y + P P S + F L I +
Sbjct: 577 SELVPRSVGAGHVVAKVRAVDPDS-GYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRS 635
Query: 173 LDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPK 214
LD + + V+D G PPL + T+ V+++++ Q PK
Sbjct: 636 LDETEAPRHRLLVLVKDHGEPPLTATATVLVSLVES-GQAPK 676
>AF152313-1|AAD43707.1| 936|Homo sapiens protocadherin alpha 5
protein.
Length = 936
Score = 87.8 bits (208), Expect = 2e-16
Identities = 106/443 (23%), Positives = 176/443 (39%), Gaps = 31/443 (6%)
Query: 9 FFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAAVGIVPGSKN--LTLLRALDR 65
+ I E+ G+ +G ++ + G +L R+ KG + +N L + +DR
Sbjct: 32 YSIPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKGRGDLLEVNLQNGILFVNSRIDR 91
Query: 66 EE---KIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXX 122
EE + ++++ V DR P V V V V D+NDN P++ + + E+
Sbjct: 92 EELCRRRAECSIHLEVIVDR-----PLQVFHVEVAVKDINDNPPRFSRQEQRLFILESRM 146
Query: 123 XXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPI---IVVKKPLDFETVN 179
SD D G ++ L Y + P + + NE E +V++K LD E
Sbjct: 147 PDSRFPLEGASDLDI-GANAQLRYRLNPNEYFDLDVKTNEEETNFLELVLRKSLDREETQ 205
Query: 180 NFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPG 239
+ + D G P L L + VLDA+D P+F Y L ++A GT +
Sbjct: 206 EHRLLVIATDGGKPELTGTVQLLINVLDANDNAPEFDKSIYNVRLLENAPSGTLVI---- 261
Query: 240 PISAADQDLGINAPLQYSSTG----DHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKA 295
++A+D D GIN + Y + D K ++N +TG++ +L E S I
Sbjct: 262 KLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGEIKVNGELDYEDYNSYEI---- 317
Query: 296 TQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQ 355
+D D+ + V E A +V+ ++ +
Sbjct: 318 -NIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVKEDAPLSTVIALISVSDR 376
Query: 356 NTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSISND--- 412
++ + F N ++L +LD E+ S Y V D S
Sbjct: 377 DSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSVYELVVTARDGGSPSLWA 436
Query: 413 TASINISVEDVNEWEPRFRHPQY 435
TAS+++ V DVN+ P F PQY
Sbjct: 437 TASVSVEVADVNDNAPAFAQPQY 459
Score = 78.2 bits (184), Expect = 1e-13
Identities = 92/318 (28%), Positives = 127/318 (39%), Gaps = 30/318 (9%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKN---LTLLRALDREE 67
+ ED P+ ++I +SV+ S G +T L +V KN L L ALDRE
Sbjct: 358 VKEDAPLSTVIALISVSDRDSGANGQVTCSLMPH-VPFKLVSTFKNYYSLVLDSALDRES 416
Query: 68 KIGPSNVYVNVRCDRRRTTDPSF--VIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXX 125
+VY V R PS VSV V DVNDNAP + Y V V E
Sbjct: 417 V----SVYELV-VTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGC 471
Query: 126 XXXXXXXSDRDQPG----PHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNF 181
D D +S + V P S Y+ E + ++ PLD E V
Sbjct: 472 HIFTVSARDADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQ-PLDHEEVELL 530
Query: 182 TIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKF-------TYEHYTALLPDDAEEGTFL 234
++ +D G PPL S+ TLQV VLD +D P T + L+P G +
Sbjct: 531 QFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVV 590
Query: 235 TTSPGPISAADQDLGINAPLQYS---STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTI 291
+ A D D G NA L Y + G + V TG+++ T+ L P +
Sbjct: 591 ----AKVRAVDPDSGYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRL 646
Query: 292 VLKATQVDNPDRYALATL 309
++ P A AT+
Sbjct: 647 LVLVKDHGEPPLTATATV 664
Score = 74.1 bits (174), Expect = 2e-12
Identities = 90/390 (23%), Positives = 157/390 (40%), Gaps = 26/390 (6%)
Query: 57 LTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVR 116
L L ++LDREE + + + T + + + V D NDNAP+++ + Y VR
Sbjct: 193 LVLRKSLDREETQEHRLLVIATDGGKPELTG---TVQLLINVLDANDNAPEFDKSIYNVR 249
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHY---AVLPGPHSEYLGFENELEPIIVVKKPL 173
+ E SD D+ +++ VL S+++ N E I V L
Sbjct: 250 LLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGE--IKVNGEL 307
Query: 174 DFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTF 233
D+E N++ I + D+ + PL + V +LD +D P+ T LP +E
Sbjct: 308 DYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAIT--TLFLP--VKEDAP 363
Query: 234 LTTSPGPISAADQDLGINAPLQYSSTGDHK-QLIVVNKDTGQVAATKQLIAELDPSVTIV 292
L+T IS +D+D G N + S +L+ K+ + L E +V
Sbjct: 364 LSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSVYELV 423
Query: 293 LKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTT 352
+ A +P +A A++ F Q QY+ V E PG + T++
Sbjct: 424 VTARDGGSPSLWATASVSVEVADVNDNAPA-----FAQPQYTVFVKENNPPGCHIFTVSA 478
Query: 353 ----VPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTD 407
+N S ++ V +R +++ +G+V + LD+E +QV D
Sbjct: 479 RDADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARD 538
Query: 408 S---ISNDTASINISVEDVNEWEPRFRHPQ 434
+ ++ + V D N+ P P+
Sbjct: 539 AGVPPLGSNVTLQVFVLDENDNAPALLVPR 568
Score = 32.7 bits (71), Expect = 6.0
Identities = 52/222 (23%), Positives = 88/222 (39%), Gaps = 24/222 (10%)
Query: 10 FISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEK-------GAAVGIVPGSKNLTLLRA 62
F+ E+ P G I T+S +++ ++ L E+ + V + S + L+
Sbjct: 462 FVKENNPPGCHIFTVSARDADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQP 521
Query: 63 LDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVW--DVNDNAPQW-------EGAPY 113
LD EE + + R P V+++V+ D NDNAP G
Sbjct: 522 LDHEEV-----ELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAV 576
Query: 114 AVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEP-IIVVKKP 172
+ V + D D G ++ L Y + P P S + F L I +
Sbjct: 577 SELVPRSVGAGHVVAKVRAVDPDS-GYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRS 635
Query: 173 LDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPK 214
LD + + V+D G PPL + T+ V+++++ Q PK
Sbjct: 636 LDETEAPRHRLLVLVKDHGEPPLTATATVLVSLVES-GQAPK 676
>AC005609-9|AAC34321.1| 816|Homo sapiens KIAA0345-like 9 protein.
Length = 816
Score = 87.8 bits (208), Expect = 2e-16
Identities = 106/443 (23%), Positives = 176/443 (39%), Gaps = 31/443 (6%)
Query: 9 FFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAAVGIVPGSKN--LTLLRALDR 65
+ I E+ G+ +G ++ + G +L R+ KG + +N L + +DR
Sbjct: 32 YSIPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKGRGDLLEVNLQNGILFVNSRIDR 91
Query: 66 EE---KIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXX 122
EE + ++++ V DR P V V V V D+NDN P++ + + E+
Sbjct: 92 EELCRRRAECSIHLEVIVDR-----PLQVFHVEVAVKDINDNPPRFSRQEQRLFILESRM 146
Query: 123 XXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPI---IVVKKPLDFETVN 179
SD D G ++ L Y + P + + NE E +V++K LD E
Sbjct: 147 PDSRFPLEGASDLDI-GANAQLRYRLNPNEYFDLDVKTNEEETNFLELVLRKSLDREETQ 205
Query: 180 NFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPG 239
+ + D G P L L + VLDA+D P+F Y L ++A GT +
Sbjct: 206 EHRLLVIATDGGKPELTGTVQLLINVLDANDNAPEFDKSIYNVRLLENAPSGTLVI---- 261
Query: 240 PISAADQDLGINAPLQYSSTG----DHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKA 295
++A+D D GIN + Y + D K ++N +TG++ +L E S I
Sbjct: 262 KLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGEIKVNGELDYEDYNSYEI---- 317
Query: 296 TQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQ 355
+D D+ + V E A +V+ ++ +
Sbjct: 318 -NIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVKEDAPLSTVIALISVSDR 376
Query: 356 NTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSISND--- 412
++ + F N ++L +LD E+ S Y V D S
Sbjct: 377 DSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSVYELVVTARDGGSPSLWA 436
Query: 413 TASINISVEDVNEWEPRFRHPQY 435
TAS+++ V DVN+ P F PQY
Sbjct: 437 TASVSVEVADVNDNAPAFAQPQY 459
Score = 78.2 bits (184), Expect = 1e-13
Identities = 92/318 (28%), Positives = 127/318 (39%), Gaps = 30/318 (9%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKN---LTLLRALDREE 67
+ ED P+ ++I +SV+ S G +T L +V KN L L ALDRE
Sbjct: 358 VKEDAPLSTVIALISVSDRDSGANGQVTCSLMPH-VPFKLVSTFKNYYSLVLDSALDRES 416
Query: 68 KIGPSNVYVNVRCDRRRTTDPSF--VIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXX 125
+VY V R PS VSV V DVNDNAP + Y V V E
Sbjct: 417 V----SVYELV-VTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGC 471
Query: 126 XXXXXXXSDRDQPG----PHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNF 181
D D +S + V P S Y+ E + ++ PLD E V
Sbjct: 472 HIFTVSARDADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQ-PLDHEEVELL 530
Query: 182 TIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKF-------TYEHYTALLPDDAEEGTFL 234
++ +D G PPL S+ TLQV VLD +D P T + L+P G +
Sbjct: 531 QFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVV 590
Query: 235 TTSPGPISAADQDLGINAPLQYS---STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTI 291
+ A D D G NA L Y + G + V TG+++ T+ L P +
Sbjct: 591 ----AKVRAVDPDSGYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRL 646
Query: 292 VLKATQVDNPDRYALATL 309
++ P A AT+
Sbjct: 647 LVLVKDHGEPPLTATATV 664
Score = 74.1 bits (174), Expect = 2e-12
Identities = 90/390 (23%), Positives = 157/390 (40%), Gaps = 26/390 (6%)
Query: 57 LTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVR 116
L L ++LDREE + + + T + + + V D NDNAP+++ + Y VR
Sbjct: 193 LVLRKSLDREETQEHRLLVIATDGGKPELTG---TVQLLINVLDANDNAPEFDKSIYNVR 249
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHY---AVLPGPHSEYLGFENELEPIIVVKKPL 173
+ E SD D+ +++ VL S+++ N E I V L
Sbjct: 250 LLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGE--IKVNGEL 307
Query: 174 DFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTF 233
D+E N++ I + D+ + PL + V +LD +D P+ T LP +E
Sbjct: 308 DYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAIT--TLFLP--VKEDAP 363
Query: 234 LTTSPGPISAADQDLGINAPLQYSSTGDHK-QLIVVNKDTGQVAATKQLIAELDPSVTIV 292
L+T IS +D+D G N + S +L+ K+ + L E +V
Sbjct: 364 LSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSVYELV 423
Query: 293 LKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTT 352
+ A +P +A A++ F Q QY+ V E PG + T++
Sbjct: 424 VTARDGGSPSLWATASVSVEVADVNDNAPA-----FAQPQYTVFVKENNPPGCHIFTVSA 478
Query: 353 ----VPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTD 407
+N S ++ V +R +++ +G+V + LD+E +QV D
Sbjct: 479 RDADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARD 538
Query: 408 S---ISNDTASINISVEDVNEWEPRFRHPQ 434
+ ++ + V D N+ P P+
Sbjct: 539 AGVPPLGSNVTLQVFVLDENDNAPALLVPR 568
Score = 32.7 bits (71), Expect = 6.0
Identities = 52/222 (23%), Positives = 88/222 (39%), Gaps = 24/222 (10%)
Query: 10 FISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEK-------GAAVGIVPGSKNLTLLRA 62
F+ E+ P G I T+S +++ ++ L E+ + V + S + L+
Sbjct: 462 FVKENNPPGCHIFTVSARDADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQP 521
Query: 63 LDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVW--DVNDNAPQW-------EGAPY 113
LD EE + + R P V+++V+ D NDNAP G
Sbjct: 522 LDHEEV-----ELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAV 576
Query: 114 AVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEP-IIVVKKP 172
+ V + D D G ++ L Y + P P S + F L I +
Sbjct: 577 SELVPRSVGAGHVVAKVRAVDPDS-GYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRS 635
Query: 173 LDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPK 214
LD + + V+D G PPL + T+ V+++++ Q PK
Sbjct: 636 LDETEAPRHRLLVLVKDHGEPPLTATATVLVSLVES-GQAPK 676
>BC031837-1|AAH31837.1| 800|Homo sapiens protocadherin beta 10
protein.
Length = 800
Score = 87.4 bits (207), Expect = 2e-16
Identities = 96/392 (24%), Positives = 162/392 (41%), Gaps = 30/392 (7%)
Query: 56 NLTLLRALDREEKIGPSN---VYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAP 112
NL LDRE+ GP +Y + D DP + +RV D+ND+AP ++
Sbjct: 83 NLLTNEKLDREKLCGPKEPCMLYFQILMD-----DPFQIYRAELRVRDINDHAPVFQDKE 137
Query: 113 YAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGP--HSEYLGF-ENELEPIIVV 169
+++SE D D G + +Y + P H G E + P +V+
Sbjct: 138 TVLKISENTAEGTAFRLERAQDPDG-GLNGIQNYTISPNSFFHINISGGDEGMIYPELVL 196
Query: 170 KKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAE 229
K LD E ++ L D GSP +T+++ VLD +D P+F Y P+++
Sbjct: 197 DKALDREEQGELSLTLTALDGGSPSRSGTSTVRIVVLDVNDNAPQFAQALYETQAPENSP 256
Query: 230 EGTFLTTSPGPISAADQDLGINAPLQYS---STGDHKQLIVVNKDTGQVAATKQLIAELD 286
G FL + A D D G+NA + YS ++ + + +N +G++ + L EL
Sbjct: 257 IG-FLIVK---VWAEDVDSGVNAEVSYSFFDASENIRTTFQINPFSGEIFLRELLDYELV 312
Query: 287 PSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSV 346
S I ++A +D A + + +S +V+E SP +
Sbjct: 313 NSYKINIQA--MDGGGLSARCRVLVEVLDTNDNPP-----ELIVSSFSNSVAEN-SPETP 364
Query: 347 LLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVT 406
L +++ + + + FL K ++ N +I +LD E + Y + VT
Sbjct: 365 LAVFKINDRDSGENGKMVCYIQENLPFLLKPSVENFYILITEGALDREIRAEYNITITVT 424
Query: 407 DSIS---NDTASINISVEDVNEWEPRFRHPQY 435
D + +I + V DVN+ P F Y
Sbjct: 425 DLGTPRLKTEHNITVLVSDVNDNAPAFTQTSY 456
Score = 75.8 bits (178), Expect = 6e-13
Identities = 88/316 (27%), Positives = 138/316 (43%), Gaps = 30/316 (9%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLL---RALDREE 67
++E++P + + +N S + G + +QE + + P +N +L ALDRE
Sbjct: 356 VAENSP-ETPLAVFKINDRDSGENGKMVCYIQENLPFL-LKPSVENFYILITEGALDREI 413
Query: 68 KIGPSNVYVNVRC--DRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXX 125
+ N+ + V R T+ + + VS DVNDNAP + Y + V E
Sbjct: 414 R-AEYNITITVTDLGTPRLKTEHNITVLVS----DVNDNAPAFTQTSYTLFVRENNSPAL 468
Query: 126 XXXXXXXSDRDQPGPHSALHYAVLP--GPHSEYLGFE--NELEPIIVVKKPLDFETVNNF 181
+DRD G ++ + Y++LP PH N + + LD+E + F
Sbjct: 469 HIGSVSATDRDS-GTNAQVTYSLLPPQDPHLPLASLVSINADNGHLFALRSLDYEALQAF 527
Query: 182 TIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTY------EHYTALLPDDAEEGTFLT 235
++ D+GSP L + ++V VLDA+D +P Y T L+P AE G +T
Sbjct: 528 EFRVGATDRGSPALSREALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVT 587
Query: 236 TSPGPISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPSV-TIVL 293
+ A D D G NA L Y L V G+V T +L++E D + +V+
Sbjct: 588 ----KVVAVDGDSGQNAWLSYQLLKATEPGLFGVWAHNGEV-RTARLLSERDAAKHRLVV 642
Query: 294 KATQVDNPDRYALATL 309
P R A ATL
Sbjct: 643 LVKDNGEPPRSATATL 658
Score = 72.5 bits (170), Expect = 6e-12
Identities = 112/478 (23%), Positives = 178/478 (37%), Gaps = 30/478 (6%)
Query: 57 LTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVR 116
L L +ALDREE+ + + + + S V + V DVNDNAPQ+ A Y +
Sbjct: 194 LVLDKALDREEQ---GELSLTLTALDGGSPSRSGTSTVRIVVLDVNDNAPQFAQALYETQ 250
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFE-NELEPIIVVKKPLDF 175
E D D G ++ + Y+ + F+ N I +++ LD+
Sbjct: 251 APENSPIGFLIVKVWAEDVDS-GVNAEVSYSFFDASENIRTTFQINPFSGEIFLRELLDY 309
Query: 176 ETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLT 235
E VN++ I ++ D G L + + V VLD +D P+ ++ + +++ E
Sbjct: 310 ELVNSYKINIQAMDGGG--LSARCRVLVEVLDTNDNPPELIVSSFSNSVAENSPE----- 362
Query: 236 TSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATK-QLIAELDPSVTIVLK 294
T D+D G N + + L+ + + + T+ L E+ I +
Sbjct: 363 TPLAVFKINDRDSGENGKMVCYIQENLPFLLKPSVENFYILITEGALDREIRAEYNITIT 422
Query: 295 ATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASP----GSVLLTL 350
T + P L T FTQ Y+ V E SP GSV T
Sbjct: 423 VTDLGTP---RLKTEHNITVLVSDVNDNAPA--FTQTSYTLFVRENNSPALHIGSVSATD 477
Query: 351 TTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTDSI 409
N + S L +IN + G + RSLDYE + ++V TD
Sbjct: 478 RDSGTNAQVTYSLLPPQDPHLPLASLVSINADNGHLFALRSLDYEALQAFEFRVGATDRG 537
Query: 410 S---NDTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGDAG 466
S + A + + V D N+ P +P VA DGD+G
Sbjct: 538 SPALSREALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVTKVVAVDGDSG 597
Query: 467 TLA-LS---LAGQHARMFYINASGDLFLREEAIGNLNSSSLHLVATAIDSGIPPRQTS 520
A LS L +F + A + +++ LV D+G PPR +
Sbjct: 598 QNAWLSYQLLKATEPGLFGVWAHNGEVRTARLLSERDAAKHRLVVLVKDNGEPPRSAT 655
>AY358720-1|AAQ89082.1| 800|Homo sapiens PCDHB10 protein.
Length = 800
Score = 87.4 bits (207), Expect = 2e-16
Identities = 96/392 (24%), Positives = 162/392 (41%), Gaps = 30/392 (7%)
Query: 56 NLTLLRALDREEKIGPSN---VYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAP 112
NL LDRE+ GP +Y + D DP + +RV D+ND+AP ++
Sbjct: 83 NLLTNEKLDREKLCGPKEPCMLYFQILMD-----DPFQIYRAELRVRDINDHAPVFQDKE 137
Query: 113 YAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGP--HSEYLGF-ENELEPIIVV 169
+++SE D D G + +Y + P H G E + P +V+
Sbjct: 138 TVLKISENTAEGTAFRLERAQDPDG-GLNGIQNYTISPNSFFHINISGGDEGMIYPELVL 196
Query: 170 KKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAE 229
K LD E ++ L D GSP +T+++ VLD +D P+F Y P+++
Sbjct: 197 DKALDREEQGELSLTLTALDGGSPSRSGTSTVRIVVLDVNDNAPQFAQALYETQAPENSP 256
Query: 230 EGTFLTTSPGPISAADQDLGINAPLQYS---STGDHKQLIVVNKDTGQVAATKQLIAELD 286
G FL + A D D G+NA + YS ++ + + +N +G++ + L EL
Sbjct: 257 IG-FLIVK---VWAEDVDSGVNAEVSYSFFDASENIRTTFQINPFSGEIFLRELLDYELV 312
Query: 287 PSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSV 346
S I ++A +D A + + +S +V+E SP +
Sbjct: 313 NSYKINIQA--MDGGGLSARCRVLVEVLDTNDNPP-----ELIVSSFSNSVAEN-SPETP 364
Query: 347 LLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVT 406
L +++ + + + FL K ++ N +I +LD E + Y + VT
Sbjct: 365 LAVFKINDRDSGENGKMVCYIQENLPFLLKPSVENFYILITEGALDREIRAEYNITITVT 424
Query: 407 DSIS---NDTASINISVEDVNEWEPRFRHPQY 435
D + +I + V DVN+ P F Y
Sbjct: 425 DLGTPRLKTEHNITVLVSDVNDNAPAFTQTSY 456
Score = 75.8 bits (178), Expect = 6e-13
Identities = 88/316 (27%), Positives = 138/316 (43%), Gaps = 30/316 (9%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLL---RALDREE 67
++E++P + + +N S + G + +QE + + P +N +L ALDRE
Sbjct: 356 VAENSP-ETPLAVFKINDRDSGENGKMVCYIQENLPFL-LKPSVENFYILITEGALDREI 413
Query: 68 KIGPSNVYVNVRC--DRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXX 125
+ N+ + V R T+ + + VS DVNDNAP + Y + V E
Sbjct: 414 R-AEYNITITVTDLGTPRLKTEHNITVLVS----DVNDNAPAFTQTSYTLFVRENNSPAL 468
Query: 126 XXXXXXXSDRDQPGPHSALHYAVLP--GPHSEYLGFE--NELEPIIVVKKPLDFETVNNF 181
+DRD G ++ + Y++LP PH N + + LD+E + F
Sbjct: 469 HIGSVSATDRDS-GTNAQVTYSLLPPQDPHLPLASLVSINADNGHLFALRSLDYEALQAF 527
Query: 182 TIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTY------EHYTALLPDDAEEGTFLT 235
++ D+GSP L + ++V VLDA+D +P Y T L+P AE G +T
Sbjct: 528 EFRVGATDRGSPALSREALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVT 587
Query: 236 TSPGPISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPSV-TIVL 293
+ A D D G NA L Y L V G+V T +L++E D + +V+
Sbjct: 588 ----KVVAVDGDSGQNAWLSYQLLKATEPGLFGVWAHNGEV-RTARLLSERDAAKHRLVV 642
Query: 294 KATQVDNPDRYALATL 309
P R A ATL
Sbjct: 643 LVKDNGEPPRSATATL 658
Score = 72.5 bits (170), Expect = 6e-12
Identities = 112/478 (23%), Positives = 178/478 (37%), Gaps = 30/478 (6%)
Query: 57 LTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVR 116
L L +ALDREE+ + + + + S V + V DVNDNAPQ+ A Y +
Sbjct: 194 LVLDKALDREEQ---GELSLTLTALDGGSPSRSGTSTVRIVVLDVNDNAPQFAQALYETQ 250
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFE-NELEPIIVVKKPLDF 175
E D D G ++ + Y+ + F+ N I +++ LD+
Sbjct: 251 APENSPIGFLIVKVWAEDVDS-GVNAEVSYSFFDASENIRTTFQINPFSGEIFLRELLDY 309
Query: 176 ETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLT 235
E VN++ I ++ D G L + + V VLD +D P+ ++ + +++ E
Sbjct: 310 ELVNSYKINIQAMDGGG--LSARCRVLVEVLDTNDNPPELIVSSFSNSVAENSPE----- 362
Query: 236 TSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATK-QLIAELDPSVTIVLK 294
T D+D G N + + L+ + + + T+ L E+ I +
Sbjct: 363 TPLAVFKINDRDSGENGKMVCYIQENLPFLLKPSVENFYILITEGALDREIRAEYNITIT 422
Query: 295 ATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASP----GSVLLTL 350
T + P L T FTQ Y+ V E SP GSV T
Sbjct: 423 VTDLGTP---RLKTEHNITVLVSDVNDNAPA--FTQTSYTLFVRENNSPALHIGSVSATD 477
Query: 351 TTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTDSI 409
N + S L +IN + G + RSLDYE + ++V TD
Sbjct: 478 RDSGTNAQVTYSLLPPQDPHLPLASLVSINADNGHLFALRSLDYEALQAFEFRVGATDRG 537
Query: 410 S---NDTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGDAG 466
S + A + + V D N+ P +P VA DGD+G
Sbjct: 538 SPALSREALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVTKVVAVDGDSG 597
Query: 467 TLA-LS---LAGQHARMFYINASGDLFLREEAIGNLNSSSLHLVATAIDSGIPPRQTS 520
A LS L +F + A + +++ LV D+G PPR +
Sbjct: 598 QNAWLSYQLLKATEPGLFGVWAHNGEVRTARLLSERDAAKHRLVVLVKDNGEPPRSAT 655
>AF217748-1|AAK51616.1| 800|Homo sapiens protocadherin-beta10
protein.
Length = 800
Score = 87.4 bits (207), Expect = 2e-16
Identities = 96/392 (24%), Positives = 162/392 (41%), Gaps = 30/392 (7%)
Query: 56 NLTLLRALDREEKIGPSN---VYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAP 112
NL LDRE+ GP +Y + D DP + +RV D+ND+AP ++
Sbjct: 83 NLLTNEKLDREKLCGPKEPCMLYFQILMD-----DPFQIYRAELRVRDINDHAPVFQDKE 137
Query: 113 YAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGP--HSEYLGF-ENELEPIIVV 169
+++SE D D G + +Y + P H G E + P +V+
Sbjct: 138 TVLKISENTAEGTAFRLERAQDPDG-GLNGIQNYTISPNSFFHINISGGDEGMIYPELVL 196
Query: 170 KKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAE 229
K LD E ++ L D GSP +T+++ VLD +D P+F Y P+++
Sbjct: 197 DKALDREEQGELSLTLTALDGGSPSRSGTSTVRIVVLDVNDNAPQFAQALYETQAPENSP 256
Query: 230 EGTFLTTSPGPISAADQDLGINAPLQYS---STGDHKQLIVVNKDTGQVAATKQLIAELD 286
G FL + A D D G+NA + YS ++ + + +N +G++ + L EL
Sbjct: 257 IG-FLIVK---VWAEDVDSGVNAEVSYSFFDASENIRTTFQINPFSGEIFLRELLDYELV 312
Query: 287 PSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSV 346
S I ++A +D A + + +S +V+E SP +
Sbjct: 313 NSYKINIQA--MDGGGLSARCRVLVEVLDTNDNPP-----ELIVSSFSNSVAEN-SPETP 364
Query: 347 LLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVT 406
L +++ + + + FL K ++ N +I +LD E + Y + VT
Sbjct: 365 LAVFKINDRDSGENGKMVCYIQENLPFLLKPSVENFYILITEGALDREIRAEYNITITVT 424
Query: 407 DSIS---NDTASINISVEDVNEWEPRFRHPQY 435
D + +I + V DVN+ P F Y
Sbjct: 425 DLGTPRLKTEHNITVLVSDVNDNAPAFTQTSY 456
Score = 77.8 bits (183), Expect = 2e-13
Identities = 89/316 (28%), Positives = 139/316 (43%), Gaps = 30/316 (9%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLL---RALDREE 67
++E++P + + +N S + G + +QE + + P +N +L ALDRE
Sbjct: 356 VAENSP-ETPLAVFKINDRDSGENGKMVCYIQENLPFL-LKPSVENFYILITEGALDREI 413
Query: 68 KIGPSNVYVNVRC--DRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXX 125
+ N+ + V R T+ + + VS DVNDNAP + Y + V E
Sbjct: 414 R-AEYNITITVTDLGTPRLKTEHNITVLVS----DVNDNAPAFTQTSYTLFVRENNSPAL 468
Query: 126 XXXXXXXSDRDQPGPHSALHYAVLP--GPHSEYLGFE--NELEPIIVVKKPLDFETVNNF 181
+DRD G ++ + Y++LP PH N + + LD+E + F
Sbjct: 469 HIGSVSATDRDS-GTNAQVTYSLLPPQDPHLPLASLVSINADNGHLFALRSLDYEALQAF 527
Query: 182 TIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTY------EHYTALLPDDAEEGTFLT 235
++ D+GSP L S+ ++V VLDA+D +P Y T L+P AE G +T
Sbjct: 528 EFRVGATDRGSPALSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVT 587
Query: 236 TSPGPISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPSV-TIVL 293
+ A D D G NA L Y L V G+V T +L++E D + +V+
Sbjct: 588 ----KVVAVDGDSGQNAWLSYQLLKATEPGLFGVWAHNGEV-RTARLLSERDAAKHRLVV 642
Query: 294 KATQVDNPDRYALATL 309
P R A ATL
Sbjct: 643 LVKDNGEPPRSATATL 658
Score = 73.3 bits (172), Expect = 3e-12
Identities = 112/478 (23%), Positives = 178/478 (37%), Gaps = 30/478 (6%)
Query: 57 LTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVR 116
L L +ALDREE+ + + + + S V + V DVNDNAPQ+ A Y +
Sbjct: 194 LVLDKALDREEQ---GELSLTLTALDGGSPSRSGTSTVRIVVLDVNDNAPQFAQALYETQ 250
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFE-NELEPIIVVKKPLDF 175
E D D G ++ + Y+ + F+ N I +++ LD+
Sbjct: 251 APENSPIGFLIVKVWAEDVDS-GVNAEVSYSFFDASENIRTTFQINPFSGEIFLRELLDY 309
Query: 176 ETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLT 235
E VN++ I ++ D G L + + V VLD +D P+ ++ + +++ E
Sbjct: 310 ELVNSYKINIQAMDGGG--LSARCRVLVEVLDTNDNPPELIVSSFSNSVAENSPE----- 362
Query: 236 TSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATK-QLIAELDPSVTIVLK 294
T D+D G N + + L+ + + + T+ L E+ I +
Sbjct: 363 TPLAVFKINDRDSGENGKMVCYIQENLPFLLKPSVENFYILITEGALDREIRAEYNITIT 422
Query: 295 ATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASP----GSVLLTL 350
T + P L T FTQ Y+ V E SP GSV T
Sbjct: 423 VTDLGTP---RLKTEHNITVLVSDVNDNAPA--FTQTSYTLFVRENNSPALHIGSVSATD 477
Query: 351 TTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTDSI 409
N + S L +IN + G + RSLDYE + ++V TD
Sbjct: 478 RDSGTNAQVTYSLLPPQDPHLPLASLVSINADNGHLFALRSLDYEALQAFEFRVGATDRG 537
Query: 410 S---NDTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGDAG 466
S + A + + V D N+ P +P VA DGD+G
Sbjct: 538 SPALSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVTKVVAVDGDSG 597
Query: 467 TLA-LS---LAGQHARMFYINASGDLFLREEAIGNLNSSSLHLVATAIDSGIPPRQTS 520
A LS L +F + A + +++ LV D+G PPR +
Sbjct: 598 QNAWLSYQLLKATEPGLFGVWAHNGEVRTARLLSERDAAKHRLVVLVKDNGEPPRSAT 655
>AF152489-1|AAD43750.1| 800|Homo sapiens protocadherin beta 10
protein.
Length = 800
Score = 87.4 bits (207), Expect = 2e-16
Identities = 96/392 (24%), Positives = 162/392 (41%), Gaps = 30/392 (7%)
Query: 56 NLTLLRALDREEKIGPSN---VYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAP 112
NL LDRE+ GP +Y + D DP + +RV D+ND+AP ++
Sbjct: 83 NLLTNEKLDREKLCGPKEPCMLYFQILMD-----DPFQIYRAELRVRDINDHAPVFQDKE 137
Query: 113 YAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGP--HSEYLGF-ENELEPIIVV 169
+++SE D D G + +Y + P H G E + P +V+
Sbjct: 138 TVLKISENTAEGTAFRLERAQDPDG-GLNGIQNYTISPNSFFHINISGGDEGMIYPELVL 196
Query: 170 KKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAE 229
K LD E ++ L D GSP +T+++ VLD +D P+F Y P+++
Sbjct: 197 DKALDREEQGELSLTLTALDGGSPSRSGTSTVRIVVLDVNDNAPQFAQALYETQAPENSP 256
Query: 230 EGTFLTTSPGPISAADQDLGINAPLQYS---STGDHKQLIVVNKDTGQVAATKQLIAELD 286
G FL + A D D G+NA + YS ++ + + +N +G++ + L EL
Sbjct: 257 IG-FLIVK---VWAEDVDSGVNAEVSYSFFDASENIRTTFQINPFSGEIFLRELLDYELV 312
Query: 287 PSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSV 346
S I ++A +D A + + +S +V+E SP +
Sbjct: 313 NSYKINIQA--MDGGGLSARCRVLVEVLDTNDNPP-----ELIVSSFSNSVAEN-SPETP 364
Query: 347 LLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVT 406
L +++ + + + FL K ++ N +I +LD E + Y + VT
Sbjct: 365 LAVFKINDRDSGENGKMVCYIQENLPFLLKPSVENFYILITEGALDREIRAEYNITITVT 424
Query: 407 DSIS---NDTASINISVEDVNEWEPRFRHPQY 435
D + +I + V DVN+ P F Y
Sbjct: 425 DLGTPRLKTEHNITVLVSDVNDNAPAFTQTSY 456
Score = 75.8 bits (178), Expect = 6e-13
Identities = 88/316 (27%), Positives = 138/316 (43%), Gaps = 30/316 (9%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLL---RALDREE 67
++E++P + + +N S + G + +QE + + P +N +L ALDRE
Sbjct: 356 VAENSP-ETPLAVFKINDRDSGENGKMVCYIQENLPFL-LKPSVENFYILITEGALDREI 413
Query: 68 KIGPSNVYVNVRC--DRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXX 125
+ N+ + V R T+ + + VS DVNDNAP + Y + V E
Sbjct: 414 R-AEYNITITVTDLGTPRLKTEHNITVLVS----DVNDNAPAFTQTSYTLFVRENNSPAL 468
Query: 126 XXXXXXXSDRDQPGPHSALHYAVLP--GPHSEYLGFE--NELEPIIVVKKPLDFETVNNF 181
+DRD G ++ + Y++LP PH N + + LD+E + F
Sbjct: 469 HIGSVSATDRDS-GTNAQVTYSLLPPQDPHLPLASLVSINADNGHLFALRSLDYEALQAF 527
Query: 182 TIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTY------EHYTALLPDDAEEGTFLT 235
++ D+GSP L + ++V VLDA+D +P Y T L+P AE G +T
Sbjct: 528 EFRVGATDRGSPALSREALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVT 587
Query: 236 TSPGPISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPSV-TIVL 293
+ A D D G NA L Y L V G+V T +L++E D + +V+
Sbjct: 588 ----KVVAVDGDSGQNAWLSYQLLKATEPGLFGVWAHNGEV-RTARLLSERDAAKHRLVV 642
Query: 294 KATQVDNPDRYALATL 309
P R A ATL
Sbjct: 643 LVKDNGEPPRSATATL 658
Score = 72.5 bits (170), Expect = 6e-12
Identities = 112/478 (23%), Positives = 178/478 (37%), Gaps = 30/478 (6%)
Query: 57 LTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVR 116
L L +ALDREE+ + + + + S V + V DVNDNAPQ+ A Y +
Sbjct: 194 LVLDKALDREEQ---GELSLTLTALDGGSPSRSGTSTVRIVVLDVNDNAPQFAQALYETQ 250
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFE-NELEPIIVVKKPLDF 175
E D D G ++ + Y+ + F+ N I +++ LD+
Sbjct: 251 APENSPIGFLIVKVWAEDVDS-GVNAEVSYSFFDASENIRTTFQINPFSGEIFLRELLDY 309
Query: 176 ETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLT 235
E VN++ I ++ D G L + + V VLD +D P+ ++ + +++ E
Sbjct: 310 ELVNSYKINIQAMDGGG--LSARCRVLVEVLDTNDNPPELIVSSFSNSVAENSPE----- 362
Query: 236 TSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATK-QLIAELDPSVTIVLK 294
T D+D G N + + L+ + + + T+ L E+ I +
Sbjct: 363 TPLAVFKINDRDSGENGKMVCYIQENLPFLLKPSVENFYILITEGALDREIRAEYNITIT 422
Query: 295 ATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASP----GSVLLTL 350
T + P L T FTQ Y+ V E SP GSV T
Sbjct: 423 VTDLGTP---RLKTEHNITVLVSDVNDNAPA--FTQTSYTLFVRENNSPALHIGSVSATD 477
Query: 351 TTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTDSI 409
N + S L +IN + G + RSLDYE + ++V TD
Sbjct: 478 RDSGTNAQVTYSLLPPQDPHLPLASLVSINADNGHLFALRSLDYEALQAFEFRVGATDRG 537
Query: 410 S---NDTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGDAG 466
S + A + + V D N+ P +P VA DGD+G
Sbjct: 538 SPALSREALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVTKVVAVDGDSG 597
Query: 467 TLA-LS---LAGQHARMFYINASGDLFLREEAIGNLNSSSLHLVATAIDSGIPPRQTS 520
A LS L +F + A + +++ LV D+G PPR +
Sbjct: 598 QNAWLSYQLLKATEPGLFGVWAHNGEVRTARLLSERDAAKHRLVVLVKDNGEPPRSAT 655
>BC132769-1|AAI32770.1| 828|Homo sapiens protocadherin gamma
subfamily A, 9 protein.
Length = 828
Score = 87.0 bits (206), Expect = 3e-16
Identities = 102/441 (23%), Positives = 179/441 (40%), Gaps = 30/441 (6%)
Query: 9 FFISEDTPIGSIIGTLSVNG--DPSEDLGDITLRLQEKGAA--VGIVPGSKNLTLLRALD 64
+ + E+T G I+G +S + +P E L + +R+ +G + P S L +D
Sbjct: 33 YSVPEETEKGYIVGNISKDLALEPRE-LAERRVRIVSRGRTQLFSLNPRSGTLVTAGRID 91
Query: 65 REEKIGPS-NVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXX 123
REE S VN + D + + + V D+ND+AP+++ V+++E
Sbjct: 92 REELCAQSPRCLVNFKV---LVEDRVKLYGIEIEVTDINDSAPKFQAESLEVKINEIAVP 148
Query: 124 XXXXXXXXXSDRDQPGPHSALHYAVLPGPH---SEYLGFENELEPIIVVKKPLDFETVNN 180
D D G +S Y + P H + G + P +V+++ LD E
Sbjct: 149 GARYPLPEAIDPDV-GVNSLQSYQLSPNHHFSLNVQTGDNGAINPELVLERALDREEATA 207
Query: 181 FTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGP 240
+ L D G P S + VTVLD +D P F Y + ++ GT+L T+
Sbjct: 208 HHLVLTASDGGEPRRSSTVRIHVTVLDTNDNAPVFAQRIYRVKVLENVPPGTWLLTA--- 264
Query: 241 ISAADQDLGINAPLQYSSTG-DHKQ--LIVVNKDTGQVAATKQLIAELDPSVTIVLKATQ 297
+A+D D GIN + Y + KQ L +N++TG+++ K L E + ++A
Sbjct: 265 -TASDLDEGINGKVAYKFWKINEKQSLLFQLNENTGEISTAKSLDYEECSFYEMEIQAED 323
Query: 298 VDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNT 357
+ + + T + V E A G+V+L +++
Sbjct: 324 GGGLKGWTKVLISVEDVNDNRP-------EVTITSLFSPVREDAPQGTVILLFNAHDRDS 376
Query: 358 EFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSISNDTAS-- 415
+ + SF + + + ++ + LD E S Y V TD + ++
Sbjct: 377 GKNGQVVCSIQENLSFTLENSEEDYYRLLTAQILDREKASEYNITVTATDRGTPPLSTEI 436
Query: 416 -INISVEDVNEWEPRFRHPQY 435
I + V D+N+ P F Y
Sbjct: 437 HITLQVTDINDNPPAFSQASY 457
Score = 79.4 bits (187), Expect = 5e-14
Identities = 81/314 (25%), Positives = 128/314 (40%), Gaps = 24/314 (7%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRA--LDREEK 68
+ ED P G++I + + S G + +QE + LL A LDRE+
Sbjct: 356 VREDAPQGTVILLFNAHDRDSGKNGQVVCSIQENLSFTLENSEEDYYRLLTAQILDREKA 415
Query: 69 IGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXX 128
S + V R T S I ++++V D+NDN P + A Y+V + E
Sbjct: 416 ---SEYNITVTATDRGTPPLSTEIHITLQVTDINDNPPAFSQASYSVYLPENNARGTSIF 472
Query: 129 XXXXSDRDQPGPHSALHYAVLP-----GPHSEYLGFENELEPIIVVKKPLDFETVNNFTI 183
D D +S + Y++ P S Y+ ++ ++ D+E + +
Sbjct: 473 SVIAYDPDS-NENSRVIYSLAEDTIQGSPLSTYVSINSDTG-VLYALCSFDYEQFRDLQM 530
Query: 184 KLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFL---TTSPG- 239
++ D GSPPL S+ +L++ VLD +D P+ Y LP D G L + PG
Sbjct: 531 QVTASDSGSPPLSSNVSLRLFVLDQNDNAPEILY----PALPTDGSTGVELAPRSAEPGY 586
Query: 240 ---PISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKA 295
+ A D+D G NA L Y L V TG+V + L+ ++V+
Sbjct: 587 LVTKVVAVDRDSGQNAWLSYRLFKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAV 646
Query: 296 TQVDNPDRYALATL 309
P A TL
Sbjct: 647 QDHGQPPLSATVTL 660
Score = 54.0 bits (124), Expect = 2e-06
Identities = 52/194 (26%), Positives = 83/194 (42%), Gaps = 20/194 (10%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
V + V DVNDN P+ V E DRD G + + ++
Sbjct: 333 VLISVEDVNDNRPEVTITSLFSPVREDAPQGTVILLFNAHDRDS-GKNGQVVCSI----- 386
Query: 154 SEYLGF--ENELEPI--IVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDAD 209
E L F EN E ++ + LD E + + I + D+G+PPL ++ + + V D +
Sbjct: 387 QENLSFTLENSEEDYYRLLTAQILDREKASEYNITVTATDRGTPPLSTEIHITLQVTDIN 446
Query: 210 DQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQ----- 264
D P F+ Y+ LP++ GT + + + A D D N+ + YS D Q
Sbjct: 447 DNPPAFSQASYSVYLPENNARGTSIFS----VIAYDPDSNENSRVIYSLAEDTIQGSPLS 502
Query: 265 -LIVVNKDTGQVAA 277
+ +N DTG + A
Sbjct: 503 TYVSINSDTGVLYA 516
>AY358654-1|AAQ89017.1| 772|Homo sapiens CDH19 protein.
Length = 772
Score = 87.0 bits (206), Expect = 3e-16
Identities = 116/445 (26%), Positives = 183/445 (41%), Gaps = 35/445 (7%)
Query: 3 GGAVESFFISEDTPIGSI-IGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLR 61
G FF+ E+ S IG L + D + L G+ I + ++ ++
Sbjct: 44 GWVWNQFFVPEEMNTTSHHIGQLRSDLDNGNNSFQYKLLGAGAGSTFIIDERTGDIYAIQ 103
Query: 62 ALDREEK---IGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVS 118
LDREE+ I + V +++ R + FVI VS D+NDN P++ PY V
Sbjct: 104 KLDREERSLYILRAQV-IDIATGRAVEPESEFVIKVS----DINDNEPKFLDEPYEAIVP 158
Query: 119 ETXXXXXXXXXXXXSDRDQP--GPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFE 176
E SD D P G ++ L Y++L G Y E +I + +D E
Sbjct: 159 EMSPEGTLVIQVTASDADDPSSGNNARLLYSLLQG--QPYFSVE-PTTGVIRISSKMDRE 215
Query: 177 TVNNFTIKLRVQDQ-GSPPLYSDTT-LQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFL 234
+ + + ++ +D G P S TT + + + D +D P F Y + + A G
Sbjct: 216 LQDEYWVIIQAKDMIGQPGALSGTTSVLIKLSDVNDNKPIFKESLYRLTVSESAPTG--- 272
Query: 235 TTSPGPISAADQDLGINAPLQYSSTGDHKQL--IVVNKDT--GQVAATKQLIAELDPSVT 290
TS G I A D D+G NA + YS D Q I+ N +T G V K++ E
Sbjct: 273 -TSIGTIMAYDNDIGENAEMDYSIEEDDSQTFDIITNHETQEGIVILKKKVDFEHQNHYG 331
Query: 291 IVLKATQVDNPDR-YALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGS-VLL 348
I K P++ T F Y V E GS V +
Sbjct: 332 IRAKVKNHHVPEQLMKYHTEASTTFIKIQVEDVDEPPLFLLPYYVFEVFEETPQGSFVGV 391
Query: 349 TLTTVPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDS 408
T P N R+SP+++ ++ RS + F IN+ G + SLD E ++ Y + T+
Sbjct: 392 VSATDPDN---RKSPIRYSIT-RSKV--FNINDNGTITTSNSLDREISAWYNLSITATEK 445
Query: 409 ISNDTAS---INISVEDVNEWEPRF 430
+ + S + + V ++N+ P F
Sbjct: 446 YNIEQISSIPLYVQVLNINDHAPEF 470
Score = 58.0 bits (134), Expect = 1e-07
Identities = 75/318 (23%), Positives = 123/318 (38%), Gaps = 23/318 (7%)
Query: 136 DQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSP-P 194
D +++ Y +L + I ++K LD E + + ++ +V D +
Sbjct: 69 DLDNGNNSFQYKLLGAGAGSTFIIDERTGDIYAIQK-LDREERSLYILRAQVIDIATGRA 127
Query: 195 LYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPL 254
+ ++ + V D +D PKF E Y A++P+ + EGT L A D G NA L
Sbjct: 128 VEPESEFVIKVSDINDNEPKFLDEPYEAIVPEMSPEGT-LVIQVTASDADDPSSGNNARL 186
Query: 255 QYSSTGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKA-TQVDNPDRYALATLXXXX 313
YS + V TG + + ++ EL ++++A + P + T
Sbjct: 187 LYSLL-QGQPYFSVEPTTGVIRISSKMDRELQDEYWVIIQAKDMIGQPGALSGTTSVLIK 245
Query: 314 XXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNT-EFRESPLQFYVSDRS 372
F + Y TVSE A G+ + T+ + E E D
Sbjct: 246 LSDVNDNKPI----FKESLYRLTVSESAPTGTSIGTIMAYDNDIGENAEMDYSIEEDDSQ 301
Query: 373 FLDKFAINNA--GEVILRRSLDYETTSNYFYQVMVTD----------SISNDTASINISV 420
D + G VIL++ +D+E ++Y + V + T I I V
Sbjct: 302 TFDIITNHETQEGIVILKKKVDFEHQNHYGIRAKVKNHHVPEQLMKYHTEASTTFIKIQV 361
Query: 421 EDVNEWEPRFRHPQYEFE 438
EDV+E P F P Y FE
Sbjct: 362 EDVDE-PPLFLLPYYVFE 378
>AJ007607-1|CAC13126.1| 772|Homo sapiens cadherin-19 protein.
Length = 772
Score = 87.0 bits (206), Expect = 3e-16
Identities = 116/445 (26%), Positives = 183/445 (41%), Gaps = 35/445 (7%)
Query: 3 GGAVESFFISEDTPIGSI-IGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLR 61
G FF+ E+ S IG L + D + L G+ I + ++ ++
Sbjct: 44 GWVWNQFFVPEEMNTTSHHIGQLRSDLDNGNNSFQYKLLGAGAGSTFIIDERTGDIYAIQ 103
Query: 62 ALDREEK---IGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVS 118
LDREE+ I + V +++ R + FVI VS D+NDN P++ PY V
Sbjct: 104 KLDREERSLYILRAQV-IDIATGRAVEPESEFVIKVS----DINDNEPKFLDEPYEAIVP 158
Query: 119 ETXXXXXXXXXXXXSDRDQP--GPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFE 176
E SD D P G ++ L Y++L G Y E +I + +D E
Sbjct: 159 EMSPEGTLVIQVTASDADDPSSGNNARLLYSLLQG--QPYFSVE-PTTGVIRISSKMDRE 215
Query: 177 TVNNFTIKLRVQDQ-GSPPLYSDTT-LQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFL 234
+ + + ++ +D G P S TT + + + D +D P F Y + + A G
Sbjct: 216 LQDEYWVIIQAKDMIGQPGALSGTTSVLIKLSDVNDNKPIFKESLYRLTVSESAPTG--- 272
Query: 235 TTSPGPISAADQDLGINAPLQYSSTGDHKQL--IVVNKDT--GQVAATKQLIAELDPSVT 290
TS G I A D D+G NA + YS D Q I+ N +T G V K++ E
Sbjct: 273 -TSIGTIMAYDNDIGENAEMDYSIEEDDSQTFDIITNHETQEGIVILKKKVDFEHQNHYG 331
Query: 291 IVLKATQVDNPDR-YALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGS-VLL 348
I K P++ T F Y V E GS V +
Sbjct: 332 IRAKVKNHHVPEQLMKYHTEASTTFIKIQVEDVDEPPLFLLPYYVFEVFEETPQGSFVGV 391
Query: 349 TLTTVPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDS 408
T P N R+SP+++ ++ RS + F IN+ G + SLD E ++ Y + T+
Sbjct: 392 VSATDPDN---RKSPIRYSIT-RSKV--FNINDNGTITTSNSLDREISAWYNLSITATEK 445
Query: 409 ISNDTAS---INISVEDVNEWEPRF 430
+ + S + + V ++N+ P F
Sbjct: 446 YNIEQISSIPLYVQVLNINDHAPEF 470
Score = 58.0 bits (134), Expect = 1e-07
Identities = 75/318 (23%), Positives = 123/318 (38%), Gaps = 23/318 (7%)
Query: 136 DQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSP-P 194
D +++ Y +L + I ++K LD E + + ++ +V D +
Sbjct: 69 DLDNGNNSFQYKLLGAGAGSTFIIDERTGDIYAIQK-LDREERSLYILRAQVIDIATGRA 127
Query: 195 LYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPL 254
+ ++ + V D +D PKF E Y A++P+ + EGT L A D G NA L
Sbjct: 128 VEPESEFVIKVSDINDNEPKFLDEPYEAIVPEMSPEGT-LVIQVTASDADDPSSGNNARL 186
Query: 255 QYSSTGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKA-TQVDNPDRYALATLXXXX 313
YS + V TG + + ++ EL ++++A + P + T
Sbjct: 187 LYSLL-QGQPYFSVEPTTGVIRISSKMDRELQDEYWVIIQAKDMIGQPGALSGTTSVLIK 245
Query: 314 XXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNT-EFRESPLQFYVSDRS 372
F + Y TVSE A G+ + T+ + E E D
Sbjct: 246 LSDVNDNKPI----FKESLYRLTVSESAPTGTSIGTIMAYDNDIGENAEMDYSIEEDDSQ 301
Query: 373 FLDKFAINNA--GEVILRRSLDYETTSNYFYQVMVTD----------SISNDTASINISV 420
D + G VIL++ +D+E ++Y + V + T I I V
Sbjct: 302 TFDIITNHETQEGIVILKKKVDFEHQNHYGIRAKVKNHHVPEQLMKYHTEASTTFIKIQV 361
Query: 421 EDVNEWEPRFRHPQYEFE 438
EDV+E P F P Y FE
Sbjct: 362 EDVDE-PPLFLLPYYVFE 378
>AF152516-1|AAD43776.1| 828|Homo sapiens protocadherin gamma A9
short form protein protein.
Length = 828
Score = 87.0 bits (206), Expect = 3e-16
Identities = 102/441 (23%), Positives = 179/441 (40%), Gaps = 30/441 (6%)
Query: 9 FFISEDTPIGSIIGTLSVNG--DPSEDLGDITLRLQEKGAA--VGIVPGSKNLTLLRALD 64
+ + E+T G I+G +S + +P E L + +R+ +G + P S L +D
Sbjct: 33 YSVPEETEKGYIVGNISKDLALEPRE-LAERRVRIVSRGRTQLFSLNPRSGTLVTAGRID 91
Query: 65 REEKIGPS-NVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXX 123
REE S VN + D + + + V D+ND+AP+++ V+++E
Sbjct: 92 REELCAQSPRCLVNFKV---LVEDRVKLYGIEIEVTDINDSAPKFQAESLEVKINEIAVP 148
Query: 124 XXXXXXXXXSDRDQPGPHSALHYAVLPGPH---SEYLGFENELEPIIVVKKPLDFETVNN 180
D D G +S Y + P H + G + P +V+++ LD E
Sbjct: 149 GARYPLPEAIDPDV-GVNSLQSYQLSPNHHFSLNVQTGDNGAINPELVLERALDREEATA 207
Query: 181 FTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGP 240
+ L D G P S + VTVLD +D P F Y + ++ GT+L T+
Sbjct: 208 HHLVLTASDGGEPRRSSTVRIHVTVLDTNDNAPVFAQRIYRVKVLENVPPGTWLLTA--- 264
Query: 241 ISAADQDLGINAPLQYSSTG-DHKQ--LIVVNKDTGQVAATKQLIAELDPSVTIVLKATQ 297
+A+D D GIN + Y + KQ L +N++TG+++ K L E + ++A
Sbjct: 265 -TASDLDEGINGKVAYKFWKINEKQSLLFQLNENTGEISTAKSLDYEECSFYEMEIQAED 323
Query: 298 VDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNT 357
+ + + T + V E A G+V+L +++
Sbjct: 324 GGGLKGWTKVLISVEDVNDNRP-------EVTITSLFSPVREDAPQGTVILLFNAHDRDS 376
Query: 358 EFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSISNDTAS-- 415
+ + SF + + + ++ + LD E S Y V TD + ++
Sbjct: 377 GKNGQVVCSIQENLSFTLENSEEDYYRLLTAQILDREKASEYNITVTATDRGTPPLSTEI 436
Query: 416 -INISVEDVNEWEPRFRHPQY 435
I + V D+N+ P F Y
Sbjct: 437 HITLQVTDINDNPPAFSQASY 457
Score = 79.4 bits (187), Expect = 5e-14
Identities = 81/314 (25%), Positives = 128/314 (40%), Gaps = 24/314 (7%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRA--LDREEK 68
+ ED P G++I + + S G + +QE + LL A LDRE+
Sbjct: 356 VREDAPQGTVILLFNAHDRDSGKNGQVVCSIQENLSFTLENSEEDYYRLLTAQILDREKA 415
Query: 69 IGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXX 128
S + V R T S I ++++V D+NDN P + A Y+V + E
Sbjct: 416 ---SEYNITVTATDRGTPPLSTEIHITLQVTDINDNPPAFSQASYSVYLPENNARGTSIF 472
Query: 129 XXXXSDRDQPGPHSALHYAVLP-----GPHSEYLGFENELEPIIVVKKPLDFETVNNFTI 183
D D +S + Y++ P S Y+ ++ ++ D+E + +
Sbjct: 473 SVIAYDPDS-NENSRVIYSLAEDTIQGSPLSTYVSINSDTG-VLYALCSFDYEQFRDLQM 530
Query: 184 KLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFL---TTSPG- 239
++ D GSPPL S+ +L++ VLD +D P+ Y LP D G L + PG
Sbjct: 531 QVTASDSGSPPLSSNVSLRLFVLDQNDNAPEILY----PALPTDGSTGVELAPRSAEPGY 586
Query: 240 ---PISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKA 295
+ A D+D G NA L Y L V TG+V + L+ ++V+
Sbjct: 587 LVTKVVAVDRDSGQNAWLSYRLFKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAV 646
Query: 296 TQVDNPDRYALATL 309
P A TL
Sbjct: 647 QDHGQPPLSATVTL 660
Score = 54.0 bits (124), Expect = 2e-06
Identities = 52/194 (26%), Positives = 83/194 (42%), Gaps = 20/194 (10%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
V + V DVNDN P+ V E DRD G + + ++
Sbjct: 333 VLISVEDVNDNRPEVTITSLFSPVREDAPQGTVILLFNAHDRDS-GKNGQVVCSI----- 386
Query: 154 SEYLGF--ENELEPI--IVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDAD 209
E L F EN E ++ + LD E + + I + D+G+PPL ++ + + V D +
Sbjct: 387 QENLSFTLENSEEDYYRLLTAQILDREKASEYNITVTATDRGTPPLSTEIHITLQVTDIN 446
Query: 210 DQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQ----- 264
D P F+ Y+ LP++ GT + + + A D D N+ + YS D Q
Sbjct: 447 DNPPAFSQASYSVYLPENNARGTSIFS----VIAYDPDSNENSRVIYSLAEDTIQGSPLS 502
Query: 265 -LIVVNKDTGQVAA 277
+ +N DTG + A
Sbjct: 503 TYVSINSDTGVLYA 516
>AF152329-1|AAD43723.1| 932|Homo sapiens protocadherin gamma A9
protein.
Length = 932
Score = 87.0 bits (206), Expect = 3e-16
Identities = 102/441 (23%), Positives = 179/441 (40%), Gaps = 30/441 (6%)
Query: 9 FFISEDTPIGSIIGTLSVNG--DPSEDLGDITLRLQEKGAA--VGIVPGSKNLTLLRALD 64
+ + E+T G I+G +S + +P E L + +R+ +G + P S L +D
Sbjct: 33 YSVPEETEKGYIVGNISKDLALEPRE-LAERRVRIVSRGRTQLFSLNPRSGTLVTAGRID 91
Query: 65 REEKIGPS-NVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXX 123
REE S VN + D + + + V D+ND+AP+++ V+++E
Sbjct: 92 REELCAQSPRCLVNFKV---LVEDRVKLYGIEIEVTDINDSAPKFQAESLEVKINEIAVP 148
Query: 124 XXXXXXXXXSDRDQPGPHSALHYAVLPGPH---SEYLGFENELEPIIVVKKPLDFETVNN 180
D D G +S Y + P H + G + P +V+++ LD E
Sbjct: 149 GARYPLPEAIDPDV-GVNSLQSYQLSPNHHFSLNVQTGDNGAINPELVLERALDREEATA 207
Query: 181 FTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGP 240
+ L D G P S + VTVLD +D P F Y + ++ GT+L T+
Sbjct: 208 HHLVLTASDGGEPRRSSTVRIHVTVLDTNDNAPVFAQRIYRVKVLENVPPGTWLLTA--- 264
Query: 241 ISAADQDLGINAPLQYSSTG-DHKQ--LIVVNKDTGQVAATKQLIAELDPSVTIVLKATQ 297
+A+D D GIN + Y + KQ L +N++TG+++ K L E + ++A
Sbjct: 265 -TASDLDEGINGKVAYKFWKINEKQSLLFQLNENTGEISTAKSLDYEECSFYEMEIQAED 323
Query: 298 VDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNT 357
+ + + T + V E A G+V+L +++
Sbjct: 324 GGGLKGWTKVLISVEDVNDNRP-------EVTITSLFSPVREDAPQGTVILLFNAHDRDS 376
Query: 358 EFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSISNDTAS-- 415
+ + SF + + + ++ + LD E S Y V TD + ++
Sbjct: 377 GKNGQVVCSIQENLSFTLENSEEDYYRLLTAQILDREKASEYNITVTATDRGTPPLSTEI 436
Query: 416 -INISVEDVNEWEPRFRHPQY 435
I + V D+N+ P F Y
Sbjct: 437 HITLQVTDINDNPPAFSQASY 457
Score = 79.4 bits (187), Expect = 5e-14
Identities = 81/314 (25%), Positives = 128/314 (40%), Gaps = 24/314 (7%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRA--LDREEK 68
+ ED P G++I + + S G + +QE + LL A LDRE+
Sbjct: 356 VREDAPQGTVILLFNAHDRDSGKNGQVVCSIQENLSFTLENSEEDYYRLLTAQILDREKA 415
Query: 69 IGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXX 128
S + V R T S I ++++V D+NDN P + A Y+V + E
Sbjct: 416 ---SEYNITVTATDRGTPPLSTEIHITLQVTDINDNPPAFSQASYSVYLPENNARGTSIF 472
Query: 129 XXXXSDRDQPGPHSALHYAVLP-----GPHSEYLGFENELEPIIVVKKPLDFETVNNFTI 183
D D +S + Y++ P S Y+ ++ ++ D+E + +
Sbjct: 473 SVIAYDPDS-NENSRVIYSLAEDTIQGSPLSTYVSINSDTG-VLYALCSFDYEQFRDLQM 530
Query: 184 KLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFL---TTSPG- 239
++ D GSPPL S+ +L++ VLD +D P+ Y LP D G L + PG
Sbjct: 531 QVTASDSGSPPLSSNVSLRLFVLDQNDNAPEILY----PALPTDGSTGVELAPRSAEPGY 586
Query: 240 ---PISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKA 295
+ A D+D G NA L Y L V TG+V + L+ ++V+
Sbjct: 587 LVTKVVAVDRDSGQNAWLSYRLFKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAV 646
Query: 296 TQVDNPDRYALATL 309
P A TL
Sbjct: 647 QDHGQPPLSATVTL 660
Score = 54.0 bits (124), Expect = 2e-06
Identities = 52/194 (26%), Positives = 83/194 (42%), Gaps = 20/194 (10%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
V + V DVNDN P+ V E DRD G + + ++
Sbjct: 333 VLISVEDVNDNRPEVTITSLFSPVREDAPQGTVILLFNAHDRDS-GKNGQVVCSI----- 386
Query: 154 SEYLGF--ENELEPI--IVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDAD 209
E L F EN E ++ + LD E + + I + D+G+PPL ++ + + V D +
Sbjct: 387 QENLSFTLENSEEDYYRLLTAQILDREKASEYNITVTATDRGTPPLSTEIHITLQVTDIN 446
Query: 210 DQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQ----- 264
D P F+ Y+ LP++ GT + + + A D D N+ + YS D Q
Sbjct: 447 DNPPAFSQASYSVYLPENNARGTSIFS----VIAYDPDSNENSRVIYSLAEDTIQGSPLS 502
Query: 265 -LIVVNKDTGQVAA 277
+ +N DTG + A
Sbjct: 503 TYVSINSDTGVLYA 516
>BC133708-1|AAI33709.1| 693|Homo sapiens PCDHGA3 protein protein.
Length = 693
Score = 86.2 bits (204), Expect = 5e-16
Identities = 118/533 (22%), Positives = 213/533 (39%), Gaps = 39/533 (7%)
Query: 9 FFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRA--LDR 65
+ +SE+ GS +G ++ + G +L + +R+ +G S++ +L+ A +DR
Sbjct: 32 YSVSEELDKGSFVGNIANDLGLEPRELAERGVRIVSRGRTQLFSLNSQSGSLVTAERIDR 91
Query: 66 EE---KIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXX 122
EE +I V +N+ + D + V + + D+NDNAP + +++ E
Sbjct: 92 EELCAQIPLCLVKINILVE-----DKLKIFEVEIEIKDINDNAPNFPTEELEIKIGELTV 146
Query: 123 XXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLG---FENELEPIIVVKKPLDFETVN 179
D D G +S +Y + P + E P +V+++ LD E
Sbjct: 147 PGTRFPIKTAFDPDV-GINSLQNYKLSPNDYFSLAVNSVSEGAKYPELVLERALDREKKE 205
Query: 180 NFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPG 239
+ L D G P + +QV VLDA+D P FT Y + ++ GT L T
Sbjct: 206 IHQLVLVASDGGDPVHSGNLHIQVIVLDANDNPPMFTQPEYRVSVWENVPVGTRLLT--- 262
Query: 240 PISAADQDLGINAPLQY---SSTGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKAT 296
++A D D G NA + Y G ++ +N +G+V+ K L + + ++ +K
Sbjct: 263 -VNATDPDEGFNAQVSYILDKMPGKIAEIFHLNSVSGEVSILKSL--DYEDAMFYEIKIE 319
Query: 297 QVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQN 356
D P + A + + T +++V E + G + + ++
Sbjct: 320 AQDGPGLLSRAKILVTVLDVNDNAP-----EITITSLTSSVPEEGTVGREIALIDVHDRD 374
Query: 357 TEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDS----ISND 412
+ F + + F + +I+ ++ SLD E S Y + +D +S +
Sbjct: 375 SGQNGQVEVFVLGNLPFKLEKSIDQYYRLVTATSLDREQISEYNISLRASDGGSPPLSTE 434
Query: 413 TASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGDAGTLAL-- 470
T I + V D+N+ P F H Y +++ T AL
Sbjct: 435 T-HITLHVIDINDNPPTFPHLSYS-AYIPENNPRGASIFSVTAQDPDSNNNARITYALTE 492
Query: 471 -SLAGQHARMFY-INASGDLFLREEAIGNLNSSSLHLVATAIDSGIPPRQTSV 521
+L G F IN++ + + L L+ TA DSG PP ++V
Sbjct: 493 DTLQGAPLSSFVSINSNTGVLYALRSFDYEQFRDLKLLVTASDSGNPPLSSNV 545
Score = 64.9 bits (151), Expect = 1e-09
Identities = 66/266 (24%), Positives = 107/266 (40%), Gaps = 22/266 (8%)
Query: 57 LTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVR 116
L +LDRE+ S +++R + S +++ V D+NDN P + Y+
Sbjct: 403 LVTATSLDREQI---SEYNISLRASDGGSPPLSTETHITLHVIDINDNPPTFPHLSYSAY 459
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYAV----LPG-PHSEYLGFENELEPIIVVKK 171
+ E D D ++ + YA+ L G P S ++ N ++ +
Sbjct: 460 IPENNPRGASIFSVTAQDPDSNN-NARITYALTEDTLQGAPLSSFVSI-NSNTGVLYALR 517
Query: 172 PLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEG 231
D+E + + + D G+PPL S+ +L + VLD +D P+ Y LP D G
Sbjct: 518 SFDYEQFRDLKLLVTASDSGNPPLSSNVSLNLFVLDQNDNAPEILY----PALPTDGSTG 573
Query: 232 TFL---TTSPG----PISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIA 283
L + PG + A D+D G NA L Y L V TG+V + L+
Sbjct: 574 VELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRLLKASEPGLFSVGLHTGEVRTARALLD 633
Query: 284 ELDPSVTIVLKATQVDNPDRYALATL 309
++V+ P A TL
Sbjct: 634 RDALKQSLVVAVQDHGQPPLSATVTL 659
Score = 35.9 bits (79), Expect = 0.64
Identities = 49/211 (23%), Positives = 83/211 (39%), Gaps = 13/211 (6%)
Query: 8 SFFISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQE---KGAAVG-IVPGSKNLTLLRAL 63
S +I E+ P G+ I +++ S + IT L E +GA + V + N +L AL
Sbjct: 457 SAYIPENNPRGASIFSVTAQDPDSNNNARITYALTEDTLQGAPLSSFVSINSNTGVLYAL 516
Query: 64 DREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQ-------WEGAPYAVR 116
+ ++ + V S + +++ V D NDNAP+ +G+
Sbjct: 517 RSFDYEQFRDLKLLVTASDSGNPPLSSNVSLNLFVLDQNDNAPEILYPALPTDGSTGVEL 576
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFE 176
+ DRD G ++ L Y +L + + LD +
Sbjct: 577 APRSAEPGYLVTKVVAVDRDS-GQNAWLSYRLLKASEPGLFSVGLHTGEVRTARALLDRD 635
Query: 177 TVNNFTIKLRVQDQGSPPLYSDTTLQVTVLD 207
+ ++ + VQD G PPL + TL V V D
Sbjct: 636 ALKQ-SLVVAVQDHGQPPLSATVTLTVAVAD 665
>AF152475-1|AAD43736.1| 844|Homo sapiens protocadherin alpha 10
short form protein protein.
Length = 844
Score = 86.2 bits (204), Expect = 5e-16
Identities = 91/361 (25%), Positives = 151/361 (41%), Gaps = 25/361 (6%)
Query: 57 LTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVS--VRVWDVNDNAPQWEGAPYA 114
L L + LDREE P + D + P F VS + V D NDNAP ++ Y
Sbjct: 193 LVLRKLLDREEN--PQLKLLLTATDGGK---PEFTGSVSLLILVLDANDNAPIFDRPVYE 247
Query: 115 VRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAV--LPGPHSEYLGFENELEPIIVVKKP 172
V++ E SD D+ G + + Y+ L P + NE I V
Sbjct: 248 VKMYENQVNQTLVIRLNASDSDE-GINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDA 306
Query: 173 LDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGT 232
+DFE N + I + V D+G+PP+ T+ V +LD +D +P+ + + +DA+ GT
Sbjct: 307 IDFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDAQVGT 366
Query: 233 FLTTSPGPISAADQDLGINAPLQYSSTGDHK-QLIVVNKDTGQVAATKQLIAELDPSVTI 291
+ IS +D D G N + S T +L+ K+ + L E + +
Sbjct: 367 VIAL----ISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYEL 422
Query: 292 VLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLT 351
V+ A +P +A A++ F Q +Y+ V E PG + T++
Sbjct: 423 VVTARDGGSPPLWATASVSVEVADVNDNAPA-----FAQSEYTVFVKENNPPGCHIFTVS 477
Query: 352 T----VPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVT 406
+N S ++ + +RS +++ +G+V + LD+E +QV
Sbjct: 478 AWDADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSAR 537
Query: 407 D 407
D
Sbjct: 538 D 538
Score = 82.2 bits (194), Expect = 7e-15
Identities = 93/387 (24%), Positives = 152/387 (39%), Gaps = 30/387 (7%)
Query: 63 LDREEKIGPS---NVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSE 119
+DREE G S ++++ V DR P V V V V D+NDN P++ + + E
Sbjct: 89 IDREELCGRSVECSIHLEVIVDR-----PLQVFHVDVEVKDINDNPPRFSVTEQKLSIPE 143
Query: 120 TXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELE----PIIVVKKPLDF 175
+ SD D G ++ L Y + P + L N+ + P++V++K LD
Sbjct: 144 SRLLDSRFPLEGASDADV-GENALLTYKLSPNEYF-VLDIINKKDKDKFPVLVLRKLLDR 201
Query: 176 ETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLT 235
E + L D G P +L + VLDA+D P F Y + ++ T +
Sbjct: 202 EENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYEVKMYENQVNQTLVI 261
Query: 236 TSPGPISAADQDLGINAPLQYSSTG----DHKQLIVVNKDTGQVAATKQLIAELDPSVTI 291
++A+D D GIN + YS + ++ +N+ TG++ + E + I
Sbjct: 262 R----LNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDAIDFEDSNTYEI 317
Query: 292 VLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLT 351
+ T NP T+ + S V E A G+V+ ++
Sbjct: 318 HVDVTDKGNPPMVGHCTVLVELLDENDNSP-----EVIVTSLSLPVKEDAQVGTVIALIS 372
Query: 352 TVPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSISN 411
++ F N ++L +LD E S Y V D S
Sbjct: 373 VSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYELVVTARDGGSP 432
Query: 412 D---TASINISVEDVNEWEPRFRHPQY 435
TAS+++ V DVN+ P F +Y
Sbjct: 433 PLWATASVSVEVADVNDNAPAFAQSEY 459
Score = 68.9 bits (161), Expect = 7e-11
Identities = 86/315 (27%), Positives = 127/315 (40%), Gaps = 24/315 (7%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKN---LTLLRALDREE 67
+ ED +G++I +SV+ S G +T L +V KN L L ALDRE
Sbjct: 358 VKEDAQVGTVIALISVSDHDSGANGQVTCSLTPH-VPFKLVSTYKNYYSLVLDSALDRER 416
Query: 68 KIGPSNVYVNVRCDRRRTTDPSFVIP-VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXX 126
+ Y V R + P + VSV V DVNDNAP + + Y V V E
Sbjct: 417 V----SAYELVVTARDGGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCH 472
Query: 127 XXXXXXSDRDQPGPHSALHYAVLP---GPHS--EYLGFENELEPIIVVKKPLDFETVNNF 181
D D ++ + Y+++ G S Y+ E + ++ PLD E +
Sbjct: 473 IFTVSAWDADAQ-ENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQ-PLDHEELELL 530
Query: 182 TIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPG-- 239
++ +D G PPL S+ TLQV VLD +D P E + G
Sbjct: 531 QFQVSARDGGVPPLGSNLTLQVFVLDENDNAPALLASP-AGSAGGAVSELVLRSVVAGHV 589
Query: 240 --PISAADQDLGINAPLQY---SSTGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLK 294
+ A D D G NA L Y S+ + V TG+++ T+ L P +++
Sbjct: 590 VAKVRAVDADSGYNAWLSYELQSAAVGARIPFRVGLYTGEISTTRALDETDSPRQRLLVL 649
Query: 295 ATQVDNPDRYALATL 309
P A AT+
Sbjct: 650 VKDHGEPSLTATATV 664
>AF152306-1|AAD43700.1| 948|Homo sapiens protocadherin alpha 10
protein.
Length = 948
Score = 86.2 bits (204), Expect = 5e-16
Identities = 91/361 (25%), Positives = 151/361 (41%), Gaps = 25/361 (6%)
Query: 57 LTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVS--VRVWDVNDNAPQWEGAPYA 114
L L + LDREE P + D + P F VS + V D NDNAP ++ Y
Sbjct: 193 LVLRKLLDREEN--PQLKLLLTATDGGK---PEFTGSVSLLILVLDANDNAPIFDRPVYE 247
Query: 115 VRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAV--LPGPHSEYLGFENELEPIIVVKKP 172
V++ E SD D+ G + + Y+ L P + NE I V
Sbjct: 248 VKMYENQVNQTLVIRLNASDSDE-GINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDA 306
Query: 173 LDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGT 232
+DFE N + I + V D+G+PP+ T+ V +LD +D +P+ + + +DA+ GT
Sbjct: 307 IDFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDAQVGT 366
Query: 233 FLTTSPGPISAADQDLGINAPLQYSSTGDHK-QLIVVNKDTGQVAATKQLIAELDPSVTI 291
+ IS +D D G N + S T +L+ K+ + L E + +
Sbjct: 367 VIAL----ISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYEL 422
Query: 292 VLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLT 351
V+ A +P +A A++ F Q +Y+ V E PG + T++
Sbjct: 423 VVTARDGGSPPLWATASVSVEVADVNDNAPA-----FAQSEYTVFVKENNPPGCHIFTVS 477
Query: 352 T----VPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVT 406
+N S ++ + +RS +++ +G+V + LD+E +QV
Sbjct: 478 AWDADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSAR 537
Query: 407 D 407
D
Sbjct: 538 D 538
Score = 82.2 bits (194), Expect = 7e-15
Identities = 93/387 (24%), Positives = 152/387 (39%), Gaps = 30/387 (7%)
Query: 63 LDREEKIGPS---NVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSE 119
+DREE G S ++++ V DR P V V V V D+NDN P++ + + E
Sbjct: 89 IDREELCGRSVECSIHLEVIVDR-----PLQVFHVDVEVKDINDNPPRFSVTEQKLSIPE 143
Query: 120 TXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELE----PIIVVKKPLDF 175
+ SD D G ++ L Y + P + L N+ + P++V++K LD
Sbjct: 144 SRLLDSRFPLEGASDADV-GENALLTYKLSPNEYF-VLDIINKKDKDKFPVLVLRKLLDR 201
Query: 176 ETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLT 235
E + L D G P +L + VLDA+D P F Y + ++ T +
Sbjct: 202 EENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYEVKMYENQVNQTLVI 261
Query: 236 TSPGPISAADQDLGINAPLQYSSTG----DHKQLIVVNKDTGQVAATKQLIAELDPSVTI 291
++A+D D GIN + YS + ++ +N+ TG++ + E + I
Sbjct: 262 R----LNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDAIDFEDSNTYEI 317
Query: 292 VLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLT 351
+ T NP T+ + S V E A G+V+ ++
Sbjct: 318 HVDVTDKGNPPMVGHCTVLVELLDENDNSP-----EVIVTSLSLPVKEDAQVGTVIALIS 372
Query: 352 TVPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSISN 411
++ F N ++L +LD E S Y V D S
Sbjct: 373 VSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYELVVTARDGGSP 432
Query: 412 D---TASINISVEDVNEWEPRFRHPQY 435
TAS+++ V DVN+ P F +Y
Sbjct: 433 PLWATASVSVEVADVNDNAPAFAQSEY 459
Score = 68.9 bits (161), Expect = 7e-11
Identities = 86/315 (27%), Positives = 127/315 (40%), Gaps = 24/315 (7%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKN---LTLLRALDREE 67
+ ED +G++I +SV+ S G +T L +V KN L L ALDRE
Sbjct: 358 VKEDAQVGTVIALISVSDHDSGANGQVTCSLTPH-VPFKLVSTYKNYYSLVLDSALDRER 416
Query: 68 KIGPSNVYVNVRCDRRRTTDPSFVIP-VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXX 126
+ Y V R + P + VSV V DVNDNAP + + Y V V E
Sbjct: 417 V----SAYELVVTARDGGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCH 472
Query: 127 XXXXXXSDRDQPGPHSALHYAVLP---GPHS--EYLGFENELEPIIVVKKPLDFETVNNF 181
D D ++ + Y+++ G S Y+ E + ++ PLD E +
Sbjct: 473 IFTVSAWDADAQ-ENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQ-PLDHEELELL 530
Query: 182 TIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPG-- 239
++ +D G PPL S+ TLQV VLD +D P E + G
Sbjct: 531 QFQVSARDGGVPPLGSNLTLQVFVLDENDNAPALLASP-AGSAGGAVSELVLRSVVAGHV 589
Query: 240 --PISAADQDLGINAPLQY---SSTGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLK 294
+ A D D G NA L Y S+ + V TG+++ T+ L P +++
Sbjct: 590 VAKVRAVDADSGYNAWLSYELQSAAVGARIPFRVGLYTGEISTTRALDETDSPRQRLLVL 649
Query: 295 ATQVDNPDRYALATL 309
P A AT+
Sbjct: 650 VKDHGEPSLTATATV 664
>AC005609-4|AAC34317.1| 844|Homo sapiens KIAA0345-like 4 protein.
Length = 844
Score = 86.2 bits (204), Expect = 5e-16
Identities = 91/361 (25%), Positives = 151/361 (41%), Gaps = 25/361 (6%)
Query: 57 LTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVS--VRVWDVNDNAPQWEGAPYA 114
L L + LDREE P + D + P F VS + V D NDNAP ++ Y
Sbjct: 193 LVLRKLLDREEN--PQLKLLLTATDGGK---PEFTGSVSLLILVLDANDNAPIFDRPVYE 247
Query: 115 VRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAV--LPGPHSEYLGFENELEPIIVVKKP 172
V++ E SD D+ G + + Y+ L P + NE I V
Sbjct: 248 VKMYENQVNQTLVIRLNASDSDE-GINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDA 306
Query: 173 LDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGT 232
+DFE N + I + V D+G+PP+ T+ V +LD +D +P+ + + +DA+ GT
Sbjct: 307 IDFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDAQVGT 366
Query: 233 FLTTSPGPISAADQDLGINAPLQYSSTGDHK-QLIVVNKDTGQVAATKQLIAELDPSVTI 291
+ IS +D D G N + S T +L+ K+ + L E + +
Sbjct: 367 VIAL----ISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYEL 422
Query: 292 VLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLT 351
V+ A +P +A A++ F Q +Y+ V E PG + T++
Sbjct: 423 VVTARDGGSPPLWATASVSVEVADVNDNAPA-----FAQSEYTVFVKENNPPGCHIFTVS 477
Query: 352 T----VPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVT 406
+N S ++ + +RS +++ +G+V + LD+E +QV
Sbjct: 478 AWDADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSAR 537
Query: 407 D 407
D
Sbjct: 538 D 538
Score = 82.2 bits (194), Expect = 7e-15
Identities = 93/387 (24%), Positives = 152/387 (39%), Gaps = 30/387 (7%)
Query: 63 LDREEKIGPS---NVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSE 119
+DREE G S ++++ V DR P V V V V D+NDN P++ + + E
Sbjct: 89 IDREELCGRSVECSIHLEVIVDR-----PLQVFHVDVEVKDINDNPPRFSVTEQKLSIPE 143
Query: 120 TXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELE----PIIVVKKPLDF 175
+ SD D G ++ L Y + P + L N+ + P++V++K LD
Sbjct: 144 SRLLDSRFPLEGASDADV-GENALLTYKLSPNEYF-VLDIINKKDKDKFPVLVLRKLLDR 201
Query: 176 ETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLT 235
E + L D G P +L + VLDA+D P F Y + ++ T +
Sbjct: 202 EENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYEVKMYENQVNQTLVI 261
Query: 236 TSPGPISAADQDLGINAPLQYSSTG----DHKQLIVVNKDTGQVAATKQLIAELDPSVTI 291
++A+D D GIN + YS + ++ +N+ TG++ + E + I
Sbjct: 262 R----LNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDAIDFEDSNTYEI 317
Query: 292 VLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLT 351
+ T NP T+ + S V E A G+V+ ++
Sbjct: 318 HVDVTDKGNPPMVGHCTVLVELLDENDNSP-----EVIVTSLSLPVKEDAQVGTVIALIS 372
Query: 352 TVPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSISN 411
++ F N ++L +LD E S Y V D S
Sbjct: 373 VSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYELVVTARDGGSP 432
Query: 412 D---TASINISVEDVNEWEPRFRHPQY 435
TAS+++ V DVN+ P F +Y
Sbjct: 433 PLWATASVSVEVADVNDNAPAFAQSEY 459
Score = 68.9 bits (161), Expect = 7e-11
Identities = 86/315 (27%), Positives = 127/315 (40%), Gaps = 24/315 (7%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKN---LTLLRALDREE 67
+ ED +G++I +SV+ S G +T L +V KN L L ALDRE
Sbjct: 358 VKEDAQVGTVIALISVSDHDSGANGQVTCSLTPH-VPFKLVSTYKNYYSLVLDSALDRER 416
Query: 68 KIGPSNVYVNVRCDRRRTTDPSFVIP-VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXX 126
+ Y V R + P + VSV V DVNDNAP + + Y V V E
Sbjct: 417 V----SAYELVVTARDGGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCH 472
Query: 127 XXXXXXSDRDQPGPHSALHYAVLP---GPHS--EYLGFENELEPIIVVKKPLDFETVNNF 181
D D ++ + Y+++ G S Y+ E + ++ PLD E +
Sbjct: 473 IFTVSAWDADAQ-ENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQ-PLDHEELELL 530
Query: 182 TIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPG-- 239
++ +D G PPL S+ TLQV VLD +D P E + G
Sbjct: 531 QFQVSARDGGVPPLGSNLTLQVFVLDENDNAPALLASP-AGSAGGAVSELVLRSVVAGHV 589
Query: 240 --PISAADQDLGINAPLQY---SSTGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLK 294
+ A D D G NA L Y S+ + V TG+++ T+ L P +++
Sbjct: 590 VAKVRAVDADSGYNAWLSYELQSAAVGARIPFRVGLYTGEISTTRALDETDSPRQRLLVL 649
Query: 295 ATQVDNPDRYALATL 309
P A AT+
Sbjct: 650 VKDHGEPSLTATATV 664
>AB208927-1|BAD92164.1| 961|Homo sapiens protocadherin gamma
subfamily A, 3 isoform 1 precursor variant protein.
Length = 961
Score = 86.2 bits (204), Expect = 5e-16
Identities = 118/533 (22%), Positives = 213/533 (39%), Gaps = 39/533 (7%)
Query: 9 FFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRA--LDR 65
+ +SE+ GS +G ++ + G +L + +R+ +G S++ +L+ A +DR
Sbjct: 62 YSVSEELDKGSFVGNIANDLGLEPRELAERGVRIVSRGRTQLFSLNSQSGSLVTAERIDR 121
Query: 66 EE---KIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXX 122
EE +I V +N+ + D + V + + D+NDNAP + +++ E
Sbjct: 122 EELCAQIPLCLVKINILVE-----DKLKIFEVEIEIKDINDNAPNFPTEELEIKIGELTV 176
Query: 123 XXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLG---FENELEPIIVVKKPLDFETVN 179
D D G +S +Y + P + E P +V+++ LD E
Sbjct: 177 PGTRFPIKTAFDPDV-GINSLQNYKLSPNDYFSLAVNSVSEGAKYPELVLERALDREKKE 235
Query: 180 NFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPG 239
+ L D G P + +QV VLDA+D P FT Y + ++ GT L T
Sbjct: 236 IHQLVLVASDGGDPVHSGNLHIQVIVLDANDNPPMFTQPEYRVSVWENVPVGTRLLT--- 292
Query: 240 PISAADQDLGINAPLQY---SSTGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKAT 296
++A D D G NA + Y G ++ +N +G+V+ K L + + ++ +K
Sbjct: 293 -VNATDPDEGFNAQVSYILDKMPGKIAEIFHLNSVSGEVSILKSL--DYEDAMFYEIKIE 349
Query: 297 QVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQN 356
D P + A + + T +++V E + G + + ++
Sbjct: 350 AQDGPGLLSRAKILVTVLDVNDNAP-----EITITSLTSSVPEEGTVGREIALIDVHDRD 404
Query: 357 TEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDS----ISND 412
+ F + + F + +I+ ++ SLD E S Y + +D +S +
Sbjct: 405 SGQNGQVEVFVLGNLPFKLEKSIDQYYRLVTATSLDREQISEYNISLRASDGGSPPLSTE 464
Query: 413 TASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGDAGTLAL-- 470
T I + V D+N+ P F H Y +++ T AL
Sbjct: 465 T-HITLHVIDINDNPPTFPHLSYS-AYIPENNPRGASIFSVTAQDPDSNNNARITYALTE 522
Query: 471 -SLAGQHARMFY-INASGDLFLREEAIGNLNSSSLHLVATAIDSGIPPRQTSV 521
+L G F IN++ + + L L+ TA DSG PP ++V
Sbjct: 523 DTLQGAPLSSFVSINSNTGVLYALRSFDYEQFRDLKLLVTASDSGNPPLSSNV 575
Score = 64.9 bits (151), Expect = 1e-09
Identities = 66/266 (24%), Positives = 107/266 (40%), Gaps = 22/266 (8%)
Query: 57 LTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVR 116
L +LDRE+ S +++R + S +++ V D+NDN P + Y+
Sbjct: 433 LVTATSLDREQI---SEYNISLRASDGGSPPLSTETHITLHVIDINDNPPTFPHLSYSAY 489
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYAV----LPG-PHSEYLGFENELEPIIVVKK 171
+ E D D ++ + YA+ L G P S ++ N ++ +
Sbjct: 490 IPENNPRGASIFSVTAQDPDSNN-NARITYALTEDTLQGAPLSSFVSI-NSNTGVLYALR 547
Query: 172 PLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEG 231
D+E + + + D G+PPL S+ +L + VLD +D P+ Y LP D G
Sbjct: 548 SFDYEQFRDLKLLVTASDSGNPPLSSNVSLNLFVLDQNDNAPEILY----PALPTDGSTG 603
Query: 232 TFL---TTSPG----PISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIA 283
L + PG + A D+D G NA L Y L V TG+V + L+
Sbjct: 604 VELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRLLKASEPGLFSVGLHTGEVRTARALLD 663
Query: 284 ELDPSVTIVLKATQVDNPDRYALATL 309
++V+ P A TL
Sbjct: 664 RDALKQSLVVAVQDHGQPPLSATVTL 689
Score = 35.9 bits (79), Expect = 0.64
Identities = 49/211 (23%), Positives = 83/211 (39%), Gaps = 13/211 (6%)
Query: 8 SFFISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQE---KGAAVG-IVPGSKNLTLLRAL 63
S +I E+ P G+ I +++ S + IT L E +GA + V + N +L AL
Sbjct: 487 SAYIPENNPRGASIFSVTAQDPDSNNNARITYALTEDTLQGAPLSSFVSINSNTGVLYAL 546
Query: 64 DREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQ-------WEGAPYAVR 116
+ ++ + V S + +++ V D NDNAP+ +G+
Sbjct: 547 RSFDYEQFRDLKLLVTASDSGNPPLSSNVSLNLFVLDQNDNAPEILYPALPTDGSTGVEL 606
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFE 176
+ DRD G ++ L Y +L + + LD +
Sbjct: 607 APRSAEPGYLVTKVVAVDRDS-GQNAWLSYRLLKASEPGLFSVGLHTGEVRTARALLDRD 665
Query: 177 TVNNFTIKLRVQDQGSPPLYSDTTLQVTVLD 207
+ ++ + VQD G PPL + TL V V D
Sbjct: 666 ALKQ-SLVVAVQDHGQPPLSATVTLTVAVAD 695
>L34056-1|AAA35622.1| 796|Homo sapiens cadherin-11 protein.
Length = 796
Score = 85.8 bits (203), Expect = 6e-16
Identities = 108/453 (23%), Positives = 180/453 (39%), Gaps = 32/453 (7%)
Query: 3 GGAVESFFISEDT--PIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSK--NLT 58
G FF+ E+ P ++G L + D + G+I L +GA V K N+
Sbjct: 54 GWVWNQFFVIEEYTGPDPVLVGRLHSDIDSGD--GNIKYILSGEGAGTIFVIDDKSGNIH 111
Query: 59 LLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVS 118
+ LDREE+ + + V D R +P V V+ D+NDN P++ Y V
Sbjct: 112 ATKTLDREERAQYTLMAQAVDRDTNRPLEPPSEFIVKVQ--DINDNPPEFLHETYHANVP 169
Query: 119 ETXXXXXXXXXXXXSDRDQP--GPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFE 176
E SD D P G + L Y++L G Y E + I +D E
Sbjct: 170 ERSNVGTSVIQVTASDADDPTYGNSAKLVYSILEG--QPYFSVEAQTGIIRTALPNMDRE 227
Query: 177 TVNNFTIKLRVQDQGS--PPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFL 234
+ + ++ +D G L T + +T+ D +D PKF Y + + A G
Sbjct: 228 AKEEYHVVIQAKDMGGHMGGLSGTTKVTITLTDVNDNPPKFPQRLYQMSVSEAAVPG--- 284
Query: 235 TTSPGPISAADQDLGINAPLQYSST-GDHKQLIVVNKD----TGQVAATKQLIAELDPSV 289
G + A D D+G N + Y+ GD + + D G + K + E + +
Sbjct: 285 -EEVGRVKAKDPDIGENGLVTYNIVDGDGMESFEITTDYETQEGVIKLKKPVDFETERAY 343
Query: 290 TIVLKATQVD-NPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLL 348
++ ++A V +P + F Y V E A+ G+V+
Sbjct: 344 SLKVEAANVHIDPKFISNGPFKDTVTVKISVEDADEPPMFLAPSYIHEVQENAAAGTVVG 403
Query: 349 TLTTVPQNTEFRESPLQFYVSDRSFLDK-FAIN-NAGEVILRRSLDYETTSNYFYQVMVT 406
+ ++ + SP+++ + + LD+ F IN G + + LD E T+ V
Sbjct: 404 RVHA--KDPDAANSPIRYSIDRHTDLDRFFTINPEDGFIKTTKPLDREETAWLNITVFAA 461
Query: 407 DSISNDTAS---INISVEDVNEWEPRFRHPQYE 436
+ + + + I V DVN+ P+F P YE
Sbjct: 462 EIHNRHQEAQVPVAIRVLDVNDNAPKFAAP-YE 493
Score = 37.5 bits (83), Expect = 0.21
Identities = 30/126 (23%), Positives = 53/126 (42%), Gaps = 9/126 (7%)
Query: 92 IPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXX----XXXXXSDRDQP--GPH--SA 143
+PV++RV DVNDNAP++ APY + E+ D+D GP +
Sbjct: 472 VPVAIRVLDVNDNAPKF-AAPYEGFICESDQTKPLSNQPIVTISADDKDDTANGPRFIFS 530
Query: 144 LHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQV 203
L ++ P+ + + + + + + + + + D G PP+ S TL +
Sbjct: 531 LPPEIIHNPNFTVRDNRDNTAGVYARRGGFSRQKQDLYLLPIVISDGGIPPMSSTNTLTI 590
Query: 204 TVLDAD 209
V D
Sbjct: 591 KVCGCD 596
>BC105111-1|AAI05112.1| 884|Homo sapiens protocadherin alpha
subfamily C, 2, isoform 2 precursor protein.
Length = 884
Score = 85.8 bits (203), Expect = 6e-16
Identities = 93/365 (25%), Positives = 152/365 (41%), Gaps = 33/365 (9%)
Query: 87 DPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHY 146
+P V V V + D+NDN+P++ Y ++VSE+ D D G +S Y
Sbjct: 127 NPVAVSAVEVEILDINDNSPRFPRPNYQLQVSESVAPGARFHIESAQDPDV-GANSVQTY 185
Query: 147 AVLPGPHSEYLGFENELEPI--------IVVKKPLDFETVNNFTIKLRVQDQGSPPLYSD 198
+ P H FE +L+P+ +V++K LD E + L D G P
Sbjct: 186 ELSPSEH-----FELDLKPLQENSKVLELVLRKGLDREQAALHHLVLTAVDGGIPARSGT 240
Query: 199 TTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQY-- 256
+ V VLD +D +P F Y L +D+ GT + ++A+D D G N L+Y
Sbjct: 241 AQISVRVLDTNDNSPAFDQSTYRVQLREDSPPGTLVV----KLNASDPDEGSNGELRYSL 296
Query: 257 -SSTGD-HKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXX 314
S T D +QL ++ TG+V L E S I ++AT DR +
Sbjct: 297 SSYTSDRERQLFSIDASTGEVRVIGGLDYEEASSYQIYVQAT-----DRGPVPMAGHCKV 351
Query: 315 XXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNT-EFRESPLQFYVSDRSF 373
+ + V E A+P +++ L+ Q++ R+ L +
Sbjct: 352 LVDIVDVNDNAPEVVLTDLYSPVPENATPNTIVAVLSVNDQDSGPNRKVSLGLEATLPFR 411
Query: 374 LDKFAINNAGEVILRRSLDYETTSNYFYQVMVTD-SISNDTA--SINISVEDVNEWEPRF 430
L+ F N+ +++ LD E + Y V TD I T+ ++ + + D+N+ P F
Sbjct: 412 LNGF--GNSYTLVVSGPLDRERVAVYNITVTATDGGIPQLTSLRTLKVEISDINDNPPSF 469
Query: 431 RHPQY 435
Y
Sbjct: 470 LEDSY 474
Score = 74.5 bits (175), Expect = 1e-12
Identities = 97/428 (22%), Positives = 167/428 (39%), Gaps = 25/428 (5%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDL-GDITLRLQE-----KGAAVGIVPGSKNLTLLRALD 64
+ ED+P G+++ L+ + DP E G++ L + I + + ++ LD
Sbjct: 266 LREDSPPGTLVVKLNAS-DPDEGSNGELRYSLSSYTSDRERQLFSIDASTGEVRVIGGLD 324
Query: 65 REEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXX 124
EE S+ + V+ R + V V + DVNDNAP+ V E
Sbjct: 325 YEEA---SSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSPVPENATPN 381
Query: 125 XXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIK 184
+D+D GP+ + + GF N +VV PLD E V + I
Sbjct: 382 TIVAVLSVNDQDS-GPNRKVSLGLEATLPFRLNGFGNSYT--LVVSGPLDRERVAVYNIT 438
Query: 185 LRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAA 244
+ D G P L S TL+V + D +D P F + Y+ + ++ G L T + A
Sbjct: 439 VTATDGGIPQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCT----VQAT 494
Query: 245 DQDLGINAPLQYSSTGDHKQ------LIVVNKDTGQVAATKQLIAELDPSVTIVLKATQV 298
D D NA + YS Q + +N +G + A E + ++A
Sbjct: 495 DPDEKENAEVTYSLLEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEAQDK 554
Query: 299 DNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTE 358
+P + T T + + +P L+T +
Sbjct: 555 GSPPLSSTVTANVYVVDMNDHAPHILYPTSTNSSAAFEMVPRTAPAGYLVTKVIAMDSDS 614
Query: 359 FRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTDSISND-TASI 416
+ + L ++++ S LD F + + GE+ R + E+ S + V+V D+ +AS+
Sbjct: 615 GQNAWLFYHLAQTSDLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSASV 674
Query: 417 NISVEDVN 424
I+V V+
Sbjct: 675 AITVAVVD 682
>BC104776-1|AAI04777.1| 884|Homo sapiens protocadherin alpha
subfamily C, 2, isoform 2 precursor protein.
Length = 884
Score = 85.8 bits (203), Expect = 6e-16
Identities = 93/365 (25%), Positives = 152/365 (41%), Gaps = 33/365 (9%)
Query: 87 DPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHY 146
+P V V V + D+NDN+P++ Y ++VSE+ D D G +S Y
Sbjct: 127 NPVAVSAVEVEILDINDNSPRFPRPNYQLQVSESVAPGARFHIESAQDPDV-GANSVQTY 185
Query: 147 AVLPGPHSEYLGFENELEPI--------IVVKKPLDFETVNNFTIKLRVQDQGSPPLYSD 198
+ P H FE +L+P+ +V++K LD E + L D G P
Sbjct: 186 ELSPSEH-----FELDLKPLQENSKVLELVLRKGLDREQAALHHLVLTAVDGGIPARSGT 240
Query: 199 TTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQY-- 256
+ V VLD +D +P F Y L +D+ GT + ++A+D D G N L+Y
Sbjct: 241 AQISVRVLDTNDNSPAFDQSTYRVQLREDSPPGTLVV----KLNASDPDEGSNGELRYSL 296
Query: 257 -SSTGD-HKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXX 314
S T D +QL ++ TG+V L E S I ++AT DR +
Sbjct: 297 SSYTSDRERQLFSIDASTGEVRVIGGLDYEEASSYQIYVQAT-----DRGPVPMAGHCKV 351
Query: 315 XXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNT-EFRESPLQFYVSDRSF 373
+ + V E A+P +++ L+ Q++ R+ L +
Sbjct: 352 LVDIVDVNDNAPEVVLTDLYSPVPENATPNTIVAVLSVNDQDSGPNRKVSLGLEATLPFR 411
Query: 374 LDKFAINNAGEVILRRSLDYETTSNYFYQVMVTD-SISNDTA--SINISVEDVNEWEPRF 430
L+ F N+ +++ LD E + Y V TD I T+ ++ + + D+N+ P F
Sbjct: 412 LNGF--GNSYTLVVSGPLDRERVAVYNITVTATDGGIPQLTSLRTLKVEISDINDNPPSF 469
Query: 431 RHPQY 435
Y
Sbjct: 470 LEDSY 474
Score = 74.5 bits (175), Expect = 1e-12
Identities = 97/428 (22%), Positives = 167/428 (39%), Gaps = 25/428 (5%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDL-GDITLRLQE-----KGAAVGIVPGSKNLTLLRALD 64
+ ED+P G+++ L+ + DP E G++ L + I + + ++ LD
Sbjct: 266 LREDSPPGTLVVKLNAS-DPDEGSNGELRYSLSSYTSDRERQLFSIDASTGEVRVIGGLD 324
Query: 65 REEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXX 124
EE S+ + V+ R + V V + DVNDNAP+ V E
Sbjct: 325 YEEA---SSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSPVPENATPN 381
Query: 125 XXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIK 184
+D+D GP+ + + GF N +VV PLD E V + I
Sbjct: 382 TIVAVLSVNDQDS-GPNRKVSLGLEATLPFRLNGFGNSYT--LVVSGPLDRERVAVYNIT 438
Query: 185 LRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAA 244
+ D G P L S TL+V + D +D P F + Y+ + ++ G L T + A
Sbjct: 439 VTATDGGIPQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCT----VQAT 494
Query: 245 DQDLGINAPLQYSSTGDHKQ------LIVVNKDTGQVAATKQLIAELDPSVTIVLKATQV 298
D D NA + YS Q + +N +G + A E + ++A
Sbjct: 495 DPDEKENAEVTYSLLEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEAQDK 554
Query: 299 DNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTE 358
+P + T T + + +P L+T +
Sbjct: 555 GSPPLSSTVTANVYVVDMNDHAPHILYPTSTNSSAAFEMVPRTAPAGYLVTKVIAMDSDS 614
Query: 359 FRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTDSISND-TASI 416
+ + L ++++ S LD F + + GE+ R + E+ S + V+V D+ +AS+
Sbjct: 615 GQNAWLFYHLAQTSDLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSASV 674
Query: 417 NISVEDVN 424
I+V V+
Sbjct: 675 AITVAVVD 682
>BC063288-1|AAH63288.1| 1007|Homo sapiens protocadherin alpha
subfamily C, 2 protein.
Length = 1007
Score = 85.8 bits (203), Expect = 6e-16
Identities = 93/365 (25%), Positives = 152/365 (41%), Gaps = 33/365 (9%)
Query: 87 DPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHY 146
+P V V V + D+NDN+P++ Y ++VSE+ D D G +S Y
Sbjct: 127 NPVAVSAVEVEILDINDNSPRFPRPNYQLQVSESVAPGARFHIESAQDPDV-GANSVQTY 185
Query: 147 AVLPGPHSEYLGFENELEPI--------IVVKKPLDFETVNNFTIKLRVQDQGSPPLYSD 198
+ P H FE +L+P+ +V++K LD E + L D G P
Sbjct: 186 ELSPSEH-----FELDLKPLQENSKVLELVLRKGLDREQAALHHLVLTAVDGGIPARSGT 240
Query: 199 TTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQY-- 256
+ V VLD +D +P F Y L +D+ GT + ++A+D D G N L+Y
Sbjct: 241 AQISVRVLDTNDNSPAFDQSTYRVQLREDSPPGTLVV----KLNASDPDEGSNGELRYSL 296
Query: 257 -SSTGD-HKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXX 314
S T D +QL ++ TG+V L E S I ++AT DR +
Sbjct: 297 SSYTSDRERQLFSIDASTGEVRVIGGLDYEEASSYQIYVQAT-----DRGPVPMAGHCKV 351
Query: 315 XXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNT-EFRESPLQFYVSDRSF 373
+ + V E A+P +++ L+ Q++ R+ L +
Sbjct: 352 LVDIVDVNDNAPEVVLTDLYSPVPENATPNTIVAVLSVNDQDSGPNRKVSLGLEATLPFR 411
Query: 374 LDKFAINNAGEVILRRSLDYETTSNYFYQVMVTD-SISNDTA--SINISVEDVNEWEPRF 430
L+ F N+ +++ LD E + Y V TD I T+ ++ + + D+N+ P F
Sbjct: 412 LNGF--GNSYTLVVSGPLDRERVAVYNITVTATDGGIPQLTSLRTLKVEISDINDNPPSF 469
Query: 431 RHPQY 435
Y
Sbjct: 470 LEDSY 474
Score = 74.5 bits (175), Expect = 1e-12
Identities = 97/428 (22%), Positives = 167/428 (39%), Gaps = 25/428 (5%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDL-GDITLRLQE-----KGAAVGIVPGSKNLTLLRALD 64
+ ED+P G+++ L+ + DP E G++ L + I + + ++ LD
Sbjct: 266 LREDSPPGTLVVKLNAS-DPDEGSNGELRYSLSSYTSDRERQLFSIDASTGEVRVIGGLD 324
Query: 65 REEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXX 124
EE S+ + V+ R + V V + DVNDNAP+ V E
Sbjct: 325 YEEA---SSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSPVPENATPN 381
Query: 125 XXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIK 184
+D+D GP+ + + GF N +VV PLD E V + I
Sbjct: 382 TIVAVLSVNDQDS-GPNRKVSLGLEATLPFRLNGFGNSYT--LVVSGPLDRERVAVYNIT 438
Query: 185 LRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAA 244
+ D G P L S TL+V + D +D P F + Y+ + ++ G L T + A
Sbjct: 439 VTATDGGIPQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCT----VQAT 494
Query: 245 DQDLGINAPLQYSSTGDHKQ------LIVVNKDTGQVAATKQLIAELDPSVTIVLKATQV 298
D D NA + YS Q + +N +G + A E + ++A
Sbjct: 495 DPDEKENAEVTYSLLEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEAQDK 554
Query: 299 DNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTE 358
+P + T T + + +P L+T +
Sbjct: 555 GSPPLSSTVTANVYVVDMNDHAPHILYPTSTNSSAAFEMVPRTAPAGYLVTKVIAMDSDS 614
Query: 359 FRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTDSISND-TASI 416
+ + L ++++ S LD F + + GE+ R + E+ S + V+V D+ +AS+
Sbjct: 615 GQNAWLFYHLAQTSDLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSASV 674
Query: 417 NISVEDVN 424
I+V V+
Sbjct: 675 AITVAVVD 682
>BC001186-1|AAH01186.1| 795|Homo sapiens protocadherin beta 5
protein.
Length = 795
Score = 85.8 bits (203), Expect = 6e-16
Identities = 99/444 (22%), Positives = 178/444 (40%), Gaps = 26/444 (5%)
Query: 3 GGAVESFFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAAVGIVPGSK--NLTL 59
G + I E+T G + L+ + G +L R+ KG + K NL L
Sbjct: 27 GSEAVRYSIPEETESGYSVANLAKDLGLGVGELATRGARMHYKGNKELLQLDIKTGNLLL 86
Query: 60 LRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSE 119
LDRE G + + + +P +++ D+ND+AP++ +++ E
Sbjct: 87 YEKLDREVMCGATEPCI--LHFQLLLENPVQFFQTDLQLTDINDHAPEFPEKEMLLKIPE 144
Query: 120 TXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH---SEYLGFENELEPIIVVKKPLDFE 176
+ D D G ++ +Y + P H + + + P +V+ K LD E
Sbjct: 145 STQPGTVFPLKIAQDFDI-GSNTVQNYTISPNSHFHVATHNRGDGRKYPELVLDKALDRE 203
Query: 177 TVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTT 236
++ L D G+PP TT+++ VLD +D P+F Y +P+++ + +
Sbjct: 204 ERPELSLTLTALDGGAPPRSGTTTIRIVVLDNNDNAPEFLQSFYEVQVPENSPLNSLVVV 263
Query: 237 SPGPISAADQDLGINAPLQYS-STGDH-KQLIVVNKDTGQVAATKQLIAELDPSVTIVLK 294
+SA D D G + Y+ GD Q V+++ T ++ + L E P + +
Sbjct: 264 ----VSARDLDAGAYGSVAYALFQGDEVTQPFVIDEKTAEIRLKRALDFEATPYYNVEIV 319
Query: 295 ATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVP 354
AT D T+ + T S+ E A P +V+ +
Sbjct: 320 AT--DGGGLSGKCTVAIEVVDVNDNAP-----ELTMSTLSSPTPENA-PETVVAVFSVSD 371
Query: 355 QNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSIS---N 411
++ + +D FL K + N ++ +R+LD E+ + Y + VTD +
Sbjct: 372 PDSGDNGRMICSIQNDLPFLLKPTLKNFYTLVTQRTLDRESQAEYNITITVTDMGTPRLK 431
Query: 412 DTASINISVEDVNEWEPRFRHPQY 435
+I + V DVN+ P F Y
Sbjct: 432 TEHNITVLVSDVNDNAPAFTQTSY 455
Score = 79.8 bits (188), Expect = 4e-14
Identities = 115/477 (24%), Positives = 176/477 (36%), Gaps = 29/477 (6%)
Query: 57 LTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVR 116
L L +ALDREE+ + + + S + + V D NDNAP++ + Y V+
Sbjct: 194 LVLDKALDREER---PELSLTLTALDGGAPPRSGTTTIRIVVLDNNDNAPEFLQSFYEVQ 250
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFE 176
V E D D G + ++ YA+ G +E I +K+ LDFE
Sbjct: 251 VPENSPLNSLVVVVSARDLDA-GAYGSVAYALFQGDEVTQPFVIDEKTAEIRLKRALDFE 309
Query: 177 TVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTT 236
+ +++ D G L T+ + V+D +D P+ T ++ P++A E T
Sbjct: 310 ATPYYNVEIVATDGGG--LSGKCTVAIEVVDVNDNAPELTMSTLSSPTPENAPE-----T 362
Query: 237 SPGPISAADQDLGINAPLQYSSTGDHKQLIVVN-KDTGQVAATKQLIAELDPSVTIVLKA 295
S +D D G N + S D L+ K+ + + L E I +
Sbjct: 363 VVAVFSVSDPDSGDNGRMICSIQNDLPFLLKPTLKNFYTLVTQRTLDRESQAEYNITITV 422
Query: 296 TQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASP----GSVLLTLT 351
T + P L T FTQ Y+ V E SP GSV T
Sbjct: 423 TDMGTP---RLKTEHNITVLVSDVNDNAPA--FTQTSYTLFVRENNSPALHIGSVSATDR 477
Query: 352 TVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTDSIS 410
N + S L +IN + G + RSLDYE + ++V TD S
Sbjct: 478 DSGTNAQVTYSLLPPQNPHLRLASLVSINADNGHLFALRSLDYEALQAFEFRVGATDRGS 537
Query: 411 ---NDTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGDAGT 467
+ A + + V D N+ P +P VA DGD+G
Sbjct: 538 PALSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVTKVVAVDGDSGQ 597
Query: 468 LA-LS---LAGQHARMFYINASGDLFLREEAIGNLNSSSLHLVATAIDSGIPPRQTS 520
A LS L +F + A + +++ LV D+G PPR +
Sbjct: 598 NAWLSYQLLKATEPGLFSMWAHNGEVRTARLLSERDAAKHRLVVLVKDNGEPPRSAT 654
Score = 79.4 bits (187), Expect = 5e-14
Identities = 88/308 (28%), Positives = 133/308 (43%), Gaps = 29/308 (9%)
Query: 19 SIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLL---RALDREEKIGPSNVY 75
+++ SV+ S D G + +Q + + P KN L R LDRE + N+
Sbjct: 362 TVVAVFSVSDPDSGDNGRMICSIQNDLPFL-LKPTLKNFYTLVTQRTLDRESQ-AEYNIT 419
Query: 76 VNVRC--DRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXS 133
+ V R T+ + + VS DVNDNAP + Y + V E +
Sbjct: 420 ITVTDMGTPRLKTEHNITVLVS----DVNDNAPAFTQTSYTLFVRENNSPALHIGSVSAT 475
Query: 134 DRDQPGPHSALHYAVLP--GPHSEYLGFE--NELEPIIVVKKPLDFETVNNFTIKLRVQD 189
DRD G ++ + Y++LP PH N + + LD+E + F ++ D
Sbjct: 476 DRDS-GTNAQVTYSLLPPQNPHLRLASLVSINADNGHLFALRSLDYEALQAFEFRVGATD 534
Query: 190 QGSPPLYSDTTLQVTVLDADDQNPKFTY------EHYTALLPDDAEEGTFLTTSPGPISA 243
+GSP L S+ ++V VLDA+D +P Y T L+P AE G +T + A
Sbjct: 535 RGSPALSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVT----KVVA 590
Query: 244 ADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPSV-TIVLKATQVDNP 301
D D G NA L Y L + G+V T +L++E D + +V+ P
Sbjct: 591 VDGDSGQNAWLSYQLLKATEPGLFSMWAHNGEV-RTARLLSERDAAKHRLVVLVKDNGEP 649
Query: 302 DRYALATL 309
R A ATL
Sbjct: 650 PRSATATL 657
>AF217753-1|AAK51620.1| 795|Homo sapiens protocadherin-beta5
protein.
Length = 795
Score = 85.8 bits (203), Expect = 6e-16
Identities = 99/444 (22%), Positives = 178/444 (40%), Gaps = 26/444 (5%)
Query: 3 GGAVESFFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAAVGIVPGSK--NLTL 59
G + I E+T G + L+ + G +L R+ KG + K NL L
Sbjct: 27 GSEAVRYSIPEETESGYSVANLAKDLGLGVGELATRGARMHYKGNKELLQLDIKTGNLLL 86
Query: 60 LRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSE 119
LDRE G + + + +P +++ D+ND+AP++ +++ E
Sbjct: 87 YEKLDREVMCGATEPCI--LHFQLLLENPVQFFQTDLQLTDINDHAPEFPEKEMLLKIPE 144
Query: 120 TXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH---SEYLGFENELEPIIVVKKPLDFE 176
+ D D G ++ +Y + P H + + + P +V+ K LD E
Sbjct: 145 STQPGTVFPLKIAQDFDI-GSNTVQNYTISPNSHFHVATHNRGDGRKYPELVLDKALDRE 203
Query: 177 TVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTT 236
++ L D G+PP TT+++ VLD +D P+F Y +P+++ + +
Sbjct: 204 ERPELSLTLTALDGGAPPRSGTTTIRIVVLDNNDNAPEFLQSFYEVQVPENSPLNSLVVV 263
Query: 237 SPGPISAADQDLGINAPLQYS-STGDH-KQLIVVNKDTGQVAATKQLIAELDPSVTIVLK 294
+SA D D G + Y+ GD Q V+++ T ++ + L E P + +
Sbjct: 264 ----VSARDLDAGAYGSVAYALFQGDEVTQPFVIDEKTAEIRLKRALDFEATPYYNVEIV 319
Query: 295 ATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVP 354
AT D T+ + T S+ E A P +V+ +
Sbjct: 320 AT--DGGGLSGKCTVAIEVVDVNDNAP-----ELTMSTLSSPTPENA-PETVVAVFSVSD 371
Query: 355 QNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSIS---N 411
++ + +D FL K + N ++ +R+LD E+ + Y + VTD +
Sbjct: 372 PDSGDNGRMICSIQNDLPFLLKPTLKNFYTLVTQRTLDRESQAEYNITITVTDMGTPRLK 431
Query: 412 DTASINISVEDVNEWEPRFRHPQY 435
+I + V DVN+ P F Y
Sbjct: 432 TEHNITVLVSDVNDNAPAFTQTSY 455
Score = 79.8 bits (188), Expect = 4e-14
Identities = 115/477 (24%), Positives = 176/477 (36%), Gaps = 29/477 (6%)
Query: 57 LTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVR 116
L L +ALDREE+ + + + S + + V D NDNAP++ + Y V+
Sbjct: 194 LVLDKALDREER---PELSLTLTALDGGAPPRSGTTTIRIVVLDNNDNAPEFLQSFYEVQ 250
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFE 176
V E D D G + ++ YA+ G +E I +K+ LDFE
Sbjct: 251 VPENSPLNSLVVVVSARDLDA-GAYGSVAYALFQGDEVTQPFVIDEKTAEIRLKRALDFE 309
Query: 177 TVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTT 236
+ +++ D G L T+ + V+D +D P+ T ++ P++A E T
Sbjct: 310 ATPYYNVEIVATDGGG--LSGKCTVAIEVVDVNDNAPELTMSTLSSPTPENAPE-----T 362
Query: 237 SPGPISAADQDLGINAPLQYSSTGDHKQLIVVN-KDTGQVAATKQLIAELDPSVTIVLKA 295
S +D D G N + S D L+ K+ + + L E I +
Sbjct: 363 VVAVFSVSDPDSGDNGRMICSIQNDLPFLLKPTLKNFYTLVTQRTLDRESQAEYNITITV 422
Query: 296 TQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASP----GSVLLTLT 351
T + P L T FTQ Y+ V E SP GSV T
Sbjct: 423 TDMGTP---RLKTEHNITVLVSDVNDNAPA--FTQTSYTLFVRENNSPALHIGSVSATDR 477
Query: 352 TVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTDSIS 410
N + S L +IN + G + RSLDYE + ++V TD S
Sbjct: 478 DSGTNAQVTYSLLPPQNPHLRLASLVSINADNGHLFALRSLDYEALQAFEFRVGATDRGS 537
Query: 411 ---NDTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGDAGT 467
+ A + + V D N+ P +P VA DGD+G
Sbjct: 538 PALSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVTKVVAVDGDSGQ 597
Query: 468 LA-LS---LAGQHARMFYINASGDLFLREEAIGNLNSSSLHLVATAIDSGIPPRQTS 520
A LS L +F + A + +++ LV D+G PPR +
Sbjct: 598 NAWLSYQLLKATEPGLFSMWAHNGEVRTARLLSERDAAKHRLVVLVKDNGEPPRSAT 654
Score = 79.4 bits (187), Expect = 5e-14
Identities = 88/308 (28%), Positives = 133/308 (43%), Gaps = 29/308 (9%)
Query: 19 SIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLL---RALDREEKIGPSNVY 75
+++ SV+ S D G + +Q + + P KN L R LDRE + N+
Sbjct: 362 TVVAVFSVSDPDSGDNGRMICSIQNDLPFL-LKPTLKNFYTLVTQRTLDRESQ-AEYNIT 419
Query: 76 VNVRC--DRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXS 133
+ V R T+ + + VS DVNDNAP + Y + V E +
Sbjct: 420 ITVTDMGTPRLKTEHNITVLVS----DVNDNAPAFTQTSYTLFVRENNSPALHIGSVSAT 475
Query: 134 DRDQPGPHSALHYAVLP--GPHSEYLGFE--NELEPIIVVKKPLDFETVNNFTIKLRVQD 189
DRD G ++ + Y++LP PH N + + LD+E + F ++ D
Sbjct: 476 DRDS-GTNAQVTYSLLPPQNPHLRLASLVSINADNGHLFALRSLDYEALQAFEFRVGATD 534
Query: 190 QGSPPLYSDTTLQVTVLDADDQNPKFTY------EHYTALLPDDAEEGTFLTTSPGPISA 243
+GSP L S+ ++V VLDA+D +P Y T L+P AE G +T + A
Sbjct: 535 RGSPALSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVT----KVVA 590
Query: 244 ADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPSV-TIVLKATQVDNP 301
D D G NA L Y L + G+V T +L++E D + +V+ P
Sbjct: 591 VDGDSGQNAWLSYQLLKATEPGLFSMWAHNGEV-RTARLLSERDAAKHRLVVLVKDNGEP 649
Query: 302 DRYALATL 309
R A ATL
Sbjct: 650 PRSATATL 657
>AF152498-1|AAD43759.1| 795|Homo sapiens protocadherin beta 5
protein.
Length = 795
Score = 85.8 bits (203), Expect = 6e-16
Identities = 99/444 (22%), Positives = 178/444 (40%), Gaps = 26/444 (5%)
Query: 3 GGAVESFFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAAVGIVPGSK--NLTL 59
G + I E+T G + L+ + G +L R+ KG + K NL L
Sbjct: 27 GSEAVRYSIPEETESGYSVANLAKDLGLGVGELATRGARMHYKGNKELLQLDIKTGNLLL 86
Query: 60 LRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSE 119
LDRE G + + + +P +++ D+ND+AP++ +++ E
Sbjct: 87 YEKLDREVMCGATEPCI--LHFQLLLENPVQFFQTDLQLTDINDHAPEFPEKEMLLKIPE 144
Query: 120 TXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH---SEYLGFENELEPIIVVKKPLDFE 176
+ D D G ++ +Y + P H + + + P +V+ K LD E
Sbjct: 145 STQPGTVFPLKIAQDFDI-GSNTVQNYTISPNSHFHVATHNRGDGRKYPELVLDKALDRE 203
Query: 177 TVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTT 236
++ L D G+PP TT+++ VLD +D P+F Y +P+++ + +
Sbjct: 204 ERPELSLTLTALDGGAPPRSGTTTIRIVVLDNNDNAPEFLQSFYEVQVPENSPLNSLVVV 263
Query: 237 SPGPISAADQDLGINAPLQYS-STGDH-KQLIVVNKDTGQVAATKQLIAELDPSVTIVLK 294
+SA D D G + Y+ GD Q V+++ T ++ + L E P + +
Sbjct: 264 ----VSARDLDAGAYGSVAYALFQGDEVTQPFVIDEKTAEIRLKRALDFEATPYYNVEIV 319
Query: 295 ATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVP 354
AT D T+ + T S+ E A P +V+ +
Sbjct: 320 AT--DGGGLSGKCTVAIEVVDVNDNAP-----ELTMSTLSSPTPENA-PETVVAVFSVSD 371
Query: 355 QNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSIS---N 411
++ + +D FL K + N ++ +R+LD E+ + Y + VTD +
Sbjct: 372 PDSGDNGRMICSIQNDLPFLLKPTLKNFYTLVTQRTLDRESQAEYNITITVTDMGTPRLK 431
Query: 412 DTASINISVEDVNEWEPRFRHPQY 435
+I + V DVN+ P F Y
Sbjct: 432 TEHNITVLVSDVNDNAPAFTQTSY 455
Score = 79.8 bits (188), Expect = 4e-14
Identities = 115/477 (24%), Positives = 176/477 (36%), Gaps = 29/477 (6%)
Query: 57 LTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVR 116
L L +ALDREE+ + + + S + + V D NDNAP++ + Y V+
Sbjct: 194 LVLDKALDREER---PELSLTLTALDGGAPPRSGTTTIRIVVLDNNDNAPEFLQSFYEVQ 250
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFE 176
V E D D G + ++ YA+ G +E I +K+ LDFE
Sbjct: 251 VPENSPLNSLVVVVSARDLDA-GAYGSVAYALFQGDEVTQPFVIDEKTAEIRLKRALDFE 309
Query: 177 TVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTT 236
+ +++ D G L T+ + V+D +D P+ T ++ P++A E T
Sbjct: 310 ATPYYNVEIVATDGGG--LSGKCTVAIEVVDVNDNAPELTMSTLSSPTPENAPE-----T 362
Query: 237 SPGPISAADQDLGINAPLQYSSTGDHKQLIVVN-KDTGQVAATKQLIAELDPSVTIVLKA 295
S +D D G N + S D L+ K+ + + L E I +
Sbjct: 363 VVAVFSVSDPDSGDNGRMICSIQNDLPFLLKPTLKNFYTLVTQRTLDRESQAEYNITITV 422
Query: 296 TQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASP----GSVLLTLT 351
T + P L T FTQ Y+ V E SP GSV T
Sbjct: 423 TDMGTP---RLKTEHNITVLVSDVNDNAPA--FTQTSYTLFVRENNSPALHIGSVSATDR 477
Query: 352 TVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTDSIS 410
N + S L +IN + G + RSLDYE + ++V TD S
Sbjct: 478 DSGTNAQVTYSLLPPQNPHLRLASLVSINADNGHLFALRSLDYEALQAFEFRVGATDRGS 537
Query: 411 ---NDTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGDAGT 467
+ A + + V D N+ P +P VA DGD+G
Sbjct: 538 PALSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVTKVVAVDGDSGQ 597
Query: 468 LA-LS---LAGQHARMFYINASGDLFLREEAIGNLNSSSLHLVATAIDSGIPPRQTS 520
A LS L +F + A + +++ LV D+G PPR +
Sbjct: 598 NAWLSYQLLKATEPGLFSMWAHNGEVRTARLLSERDAAKHRLVVLVKDNGEPPRSAT 654
Score = 79.4 bits (187), Expect = 5e-14
Identities = 88/308 (28%), Positives = 133/308 (43%), Gaps = 29/308 (9%)
Query: 19 SIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLL---RALDREEKIGPSNVY 75
+++ SV+ S D G + +Q + + P KN L R LDRE + N+
Sbjct: 362 TVVAVFSVSDPDSGDNGRMICSIQNDLPFL-LKPTLKNFYTLVTQRTLDRESQ-AEYNIT 419
Query: 76 VNVRC--DRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXS 133
+ V R T+ + + VS DVNDNAP + Y + V E +
Sbjct: 420 ITVTDMGTPRLKTEHNITVLVS----DVNDNAPAFTQTSYTLFVRENNSPALHIGSVSAT 475
Query: 134 DRDQPGPHSALHYAVLP--GPHSEYLGFE--NELEPIIVVKKPLDFETVNNFTIKLRVQD 189
DRD G ++ + Y++LP PH N + + LD+E + F ++ D
Sbjct: 476 DRDS-GTNAQVTYSLLPPQNPHLRLASLVSINADNGHLFALRSLDYEALQAFEFRVGATD 534
Query: 190 QGSPPLYSDTTLQVTVLDADDQNPKFTY------EHYTALLPDDAEEGTFLTTSPGPISA 243
+GSP L S+ ++V VLDA+D +P Y T L+P AE G +T + A
Sbjct: 535 RGSPALSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVT----KVVA 590
Query: 244 ADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPSV-TIVLKATQVDNP 301
D D G NA L Y L + G+V T +L++E D + +V+ P
Sbjct: 591 VDGDSGQNAWLSYQLLKATEPGLFSMWAHNGEV-RTARLLSERDAAKHRLVVLVKDNGEP 649
Query: 302 DRYALATL 309
R A ATL
Sbjct: 650 PRSATATL 657
>AF152474-1|AAD43735.1| 884|Homo sapiens protocadherin alpha C2
short form protein protein.
Length = 884
Score = 85.8 bits (203), Expect = 6e-16
Identities = 93/365 (25%), Positives = 152/365 (41%), Gaps = 33/365 (9%)
Query: 87 DPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHY 146
+P V V V + D+NDN+P++ Y ++VSE+ D D G +S Y
Sbjct: 127 NPVAVSAVEVEILDINDNSPRFPRPNYQLQVSESVAPGARFHIESAQDPDV-GANSVQTY 185
Query: 147 AVLPGPHSEYLGFENELEPI--------IVVKKPLDFETVNNFTIKLRVQDQGSPPLYSD 198
+ P H FE +L+P+ +V++K LD E + L D G P
Sbjct: 186 ELSPSEH-----FELDLKPLQENSKVLELVLRKGLDREQAALHHLVLTAVDGGIPARSGT 240
Query: 199 TTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQY-- 256
+ V VLD +D +P F Y L +D+ GT + ++A+D D G N L+Y
Sbjct: 241 AQISVRVLDTNDNSPAFDQSTYRVQLREDSPPGTLVV----KLNASDPDEGSNGELRYSL 296
Query: 257 -SSTGD-HKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXX 314
S T D +QL ++ TG+V L E S I ++AT DR +
Sbjct: 297 SSYTSDRERQLFSIDASTGEVRVIGGLDYEEASSYQIYVQAT-----DRGPVPMAGHCKV 351
Query: 315 XXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNT-EFRESPLQFYVSDRSF 373
+ + V E A+P +++ L+ Q++ R+ L +
Sbjct: 352 LVDIVDVNDNAPEVVLTDLYSPVPENATPNTIVAVLSVNDQDSGPNRKVSLGLEATLPFR 411
Query: 374 LDKFAINNAGEVILRRSLDYETTSNYFYQVMVTD-SISNDTA--SINISVEDVNEWEPRF 430
L+ F N+ +++ LD E + Y V TD I T+ ++ + + D+N+ P F
Sbjct: 412 LNGF--GNSYTLVVSGPLDRERVAVYNITVTATDGGIPQLTSLRTLKVEISDINDNPPSF 469
Query: 431 RHPQY 435
Y
Sbjct: 470 LEDSY 474
Score = 74.5 bits (175), Expect = 1e-12
Identities = 97/428 (22%), Positives = 167/428 (39%), Gaps = 25/428 (5%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDL-GDITLRLQE-----KGAAVGIVPGSKNLTLLRALD 64
+ ED+P G+++ L+ + DP E G++ L + I + + ++ LD
Sbjct: 266 LREDSPPGTLVVKLNAS-DPDEGSNGELRYSLSSYTSDRERQLFSIDASTGEVRVIGGLD 324
Query: 65 REEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXX 124
EE S+ + V+ R + V V + DVNDNAP+ V E
Sbjct: 325 YEEA---SSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSPVPENATPN 381
Query: 125 XXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIK 184
+D+D GP+ + + GF N +VV PLD E V + I
Sbjct: 382 TIVAVLSVNDQDS-GPNRKVSLGLEATLPFRLNGFGNSYT--LVVSGPLDRERVAVYNIT 438
Query: 185 LRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAA 244
+ D G P L S TL+V + D +D P F + Y+ + ++ G L T + A
Sbjct: 439 VTATDGGIPQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCT----VQAT 494
Query: 245 DQDLGINAPLQYSSTGDHKQ------LIVVNKDTGQVAATKQLIAELDPSVTIVLKATQV 298
D D NA + YS Q + +N +G + A E + ++A
Sbjct: 495 DPDEKENAEVTYSLLEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEAQDK 554
Query: 299 DNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTE 358
+P + T T + + +P L+T +
Sbjct: 555 GSPPLSSTVTANVYVVDMNDHAPHILYPTSTNSSAAFEMVPRTAPAGYLVTKVIAMDSDS 614
Query: 359 FRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTDSISND-TASI 416
+ + L ++++ S LD F + + GE+ R + E+ S + V+V D+ +AS+
Sbjct: 615 GQNAWLFYHLAQTSDLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSASV 674
Query: 417 NISVEDVN 424
I+V V+
Sbjct: 675 AITVAVVD 682
>AF152304-1|AAD43698.1| 1007|Homo sapiens protocadherin alpha C2
protein.
Length = 1007
Score = 85.8 bits (203), Expect = 6e-16
Identities = 93/365 (25%), Positives = 152/365 (41%), Gaps = 33/365 (9%)
Query: 87 DPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHY 146
+P V V V + D+NDN+P++ Y ++VSE+ D D G +S Y
Sbjct: 127 NPVAVSAVEVEILDINDNSPRFPRPNYQLQVSESVAPGARFHIESAQDPDV-GANSVQTY 185
Query: 147 AVLPGPHSEYLGFENELEPI--------IVVKKPLDFETVNNFTIKLRVQDQGSPPLYSD 198
+ P H FE +L+P+ +V++K LD E + L D G P
Sbjct: 186 ELSPSEH-----FELDLKPLQENSKVLELVLRKGLDREQAALHHLVLTAVDGGIPARSGT 240
Query: 199 TTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQY-- 256
+ V VLD +D +P F Y L +D+ GT + ++A+D D G N L+Y
Sbjct: 241 AQISVRVLDTNDNSPAFDQSTYRVQLREDSPPGTLVV----KLNASDPDEGSNGELRYSL 296
Query: 257 -SSTGD-HKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXX 314
S T D +QL ++ TG+V L E S I ++AT DR +
Sbjct: 297 SSYTSDRERQLFSIDASTGEVRVIGGLDYEEASSYQIYVQAT-----DRGPVPMAGHCKV 351
Query: 315 XXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNT-EFRESPLQFYVSDRSF 373
+ + V E A+P +++ L+ Q++ R+ L +
Sbjct: 352 LVDIVDVNDNAPEVVLTDLYSPVPENATPNTIVAVLSVNDQDSGPNRKVSLGLEATLPFR 411
Query: 374 LDKFAINNAGEVILRRSLDYETTSNYFYQVMVTD-SISNDTA--SINISVEDVNEWEPRF 430
L+ F N+ +++ LD E + Y V TD I T+ ++ + + D+N+ P F
Sbjct: 412 LNGF--GNSYTLVVSGPLDRERVAVYNITVTATDGGIPQLTSLRTLKVEISDINDNPPSF 469
Query: 431 RHPQY 435
Y
Sbjct: 470 LEDSY 474
Score = 74.5 bits (175), Expect = 1e-12
Identities = 97/428 (22%), Positives = 167/428 (39%), Gaps = 25/428 (5%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDL-GDITLRLQE-----KGAAVGIVPGSKNLTLLRALD 64
+ ED+P G+++ L+ + DP E G++ L + I + + ++ LD
Sbjct: 266 LREDSPPGTLVVKLNAS-DPDEGSNGELRYSLSSYTSDRERQLFSIDASTGEVRVIGGLD 324
Query: 65 REEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXX 124
EE S+ + V+ R + V V + DVNDNAP+ V E
Sbjct: 325 YEEA---SSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSPVPENATPN 381
Query: 125 XXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIK 184
+D+D GP+ + + GF N +VV PLD E V + I
Sbjct: 382 TIVAVLSVNDQDS-GPNRKVSLGLEATLPFRLNGFGNSYT--LVVSGPLDRERVAVYNIT 438
Query: 185 LRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAA 244
+ D G P L S TL+V + D +D P F + Y+ + ++ G L T + A
Sbjct: 439 VTATDGGIPQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCT----VQAT 494
Query: 245 DQDLGINAPLQYSSTGDHKQ------LIVVNKDTGQVAATKQLIAELDPSVTIVLKATQV 298
D D NA + YS Q + +N +G + A E + ++A
Sbjct: 495 DPDEKENAEVTYSLLEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEAQDK 554
Query: 299 DNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTE 358
+P + T T + + +P L+T +
Sbjct: 555 GSPPLSSTVTANVYVVDMNDHAPHILYPTSTNSSAAFEMVPRTAPAGYLVTKVIAMDSDS 614
Query: 359 FRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTDSISND-TASI 416
+ + L ++++ S LD F + + GE+ R + E+ S + V+V D+ +AS+
Sbjct: 615 GQNAWLFYHLAQTSDLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSASV 674
Query: 417 NISVEDVN 424
I+V V+
Sbjct: 675 AITVAVVD 682
>AF134474-1|AAP97251.1| 795|Homo sapiens protocadherin protein.
Length = 795
Score = 85.8 bits (203), Expect = 6e-16
Identities = 99/444 (22%), Positives = 178/444 (40%), Gaps = 26/444 (5%)
Query: 3 GGAVESFFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAAVGIVPGSK--NLTL 59
G + I E+T G + L+ + G +L R+ KG + K NL L
Sbjct: 27 GSEAVRYSIPEETESGYSVANLAKDLGLGVGELATRGARMHYKGNKELLQLDIKTGNLLL 86
Query: 60 LRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSE 119
LDRE G + + + +P +++ D+ND+AP++ +++ E
Sbjct: 87 YEKLDREVMCGATEPCI--LHFQLLLENPVQFFQTDLQLTDINDHAPEFPEKEMLLKIPE 144
Query: 120 TXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH---SEYLGFENELEPIIVVKKPLDFE 176
+ D D G ++ +Y + P H + + + P +V+ K LD E
Sbjct: 145 STQPGTVFPLKIAQDFDI-GSNTVQNYTISPNSHFHVATHNRGDGRKYPELVLDKALDRE 203
Query: 177 TVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTT 236
++ L D G+PP TT+++ VLD +D P+F Y +P+++ + +
Sbjct: 204 ERPELSLTLTALDGGAPPRSGTTTIRIVVLDNNDNAPEFLQSFYEVQVPENSPLNSLVVV 263
Query: 237 SPGPISAADQDLGINAPLQYS-STGDH-KQLIVVNKDTGQVAATKQLIAELDPSVTIVLK 294
+SA D D G + Y+ GD Q V+++ T ++ + L E P + +
Sbjct: 264 ----VSARDLDAGAYGSVAYALFQGDEVTQPFVIDEKTAEIRLKRALDFEATPYYNVEIV 319
Query: 295 ATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVP 354
AT D T+ + T S+ E A P +V+ +
Sbjct: 320 AT--DGGGLSGKCTVAIEVVDVNDNAP-----ELTMSTLSSPTPENA-PETVVAVFSVSD 371
Query: 355 QNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSIS---N 411
++ + +D FL K + N ++ +R+LD E+ + Y + VTD +
Sbjct: 372 PDSGDNGRMICSIQNDLPFLLKPTLKNFYTLVTQRTLDRESQAEYNITITVTDMGTPRLK 431
Query: 412 DTASINISVEDVNEWEPRFRHPQY 435
+I + V DVN+ P F Y
Sbjct: 432 TEHNITVLVSDVNDNAPAFTQTSY 455
Score = 79.8 bits (188), Expect = 4e-14
Identities = 115/477 (24%), Positives = 176/477 (36%), Gaps = 29/477 (6%)
Query: 57 LTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVR 116
L L +ALDREE+ + + + S + + V D NDNAP++ + Y V+
Sbjct: 194 LVLDKALDREER---PELSLTLTALDGGAPPRSGTTTIRIVVLDNNDNAPEFLQSFYEVQ 250
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFE 176
V E D D G + ++ YA+ G +E I +K+ LDFE
Sbjct: 251 VPENSPLNSLVVVVSARDLDA-GAYGSVAYALFQGDEVTQPFVIDEKTAEIRLKRALDFE 309
Query: 177 TVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTT 236
+ +++ D G L T+ + V+D +D P+ T ++ P++A E T
Sbjct: 310 ATPYYNVEIVATDGGG--LSGKCTVAIEVVDVNDNAPELTMSTLSSPTPENAPE-----T 362
Query: 237 SPGPISAADQDLGINAPLQYSSTGDHKQLIVVN-KDTGQVAATKQLIAELDPSVTIVLKA 295
S +D D G N + S D L+ K+ + + L E I +
Sbjct: 363 VVAVFSVSDPDSGDNGRMICSIQNDLPFLLKPTLKNFYTLVTQRTLDRESQAEYNITITV 422
Query: 296 TQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASP----GSVLLTLT 351
T + P L T FTQ Y+ V E SP GSV T
Sbjct: 423 TDMGTP---RLKTEHNITVLVSDVNDNAPA--FTQTSYTLFVRENNSPALHIGSVSATDR 477
Query: 352 TVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTDSIS 410
N + S L +IN + G + RSLDYE + ++V TD S
Sbjct: 478 DSGTNAQVTYSLLPPQNPHLRLASLVSINADNGHLFALRSLDYEALQAFEFRVGATDRGS 537
Query: 411 ---NDTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGDAGT 467
+ A + + V D N+ P +P VA DGD+G
Sbjct: 538 PALSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVTKVVAVDGDSGQ 597
Query: 468 LA-LS---LAGQHARMFYINASGDLFLREEAIGNLNSSSLHLVATAIDSGIPPRQTS 520
A LS L +F + A + +++ LV D+G PPR +
Sbjct: 598 NAWLSYQLLKATEPGLFSMWAHNGEVRTARLLSERDAAKHRLVVLVKDNGEPPRSAT 654
Score = 79.4 bits (187), Expect = 5e-14
Identities = 88/308 (28%), Positives = 133/308 (43%), Gaps = 29/308 (9%)
Query: 19 SIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLL---RALDREEKIGPSNVY 75
+++ SV+ S D G + +Q + + P KN L R LDRE + N+
Sbjct: 362 TVVAVFSVSDPDSGDNGRMICSIQNDLPFL-LKPTLKNFYTLVTQRTLDRESQ-AEYNIT 419
Query: 76 VNVRC--DRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXS 133
+ V R T+ + + VS DVNDNAP + Y + V E +
Sbjct: 420 ITVTDMGTPRLKTEHNITVLVS----DVNDNAPAFTQTSYTLFVRENNSPALHIGSVSAT 475
Query: 134 DRDQPGPHSALHYAVLP--GPHSEYLGFE--NELEPIIVVKKPLDFETVNNFTIKLRVQD 189
DRD G ++ + Y++LP PH N + + LD+E + F ++ D
Sbjct: 476 DRDS-GTNAQVTYSLLPPQNPHLRLASLVSINADNGHLFALRSLDYEALQAFEFRVGATD 534
Query: 190 QGSPPLYSDTTLQVTVLDADDQNPKFTY------EHYTALLPDDAEEGTFLTTSPGPISA 243
+GSP L S+ ++V VLDA+D +P Y T L+P AE G +T + A
Sbjct: 535 RGSPALSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVT----KVVA 590
Query: 244 ADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPSV-TIVLKATQVDNP 301
D D G NA L Y L + G+V T +L++E D + +V+ P
Sbjct: 591 VDGDSGQNAWLSYQLLKATEPGLFSMWAHNGEV-RTARLLSERDAAKHRLVVLVKDNGEP 649
Query: 302 DRYALATL 309
R A ATL
Sbjct: 650 PRSATATL 657
>AB209393-1|BAD92630.1| 796|Homo sapiens protocadherin beta 5
precursor variant protein.
Length = 796
Score = 85.8 bits (203), Expect = 6e-16
Identities = 99/444 (22%), Positives = 178/444 (40%), Gaps = 26/444 (5%)
Query: 3 GGAVESFFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAAVGIVPGSK--NLTL 59
G + I E+T G + L+ + G +L R+ KG + K NL L
Sbjct: 28 GSEAVRYSIPEETESGYSVANLAKDLGLGVGELATRGARMHYKGNKELLQLDIKTGNLLL 87
Query: 60 LRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSE 119
LDRE G + + + +P +++ D+ND+AP++ +++ E
Sbjct: 88 YEKLDREVMCGATEPCI--LHFQLLLENPVQFFQTDLQLTDINDHAPEFPEKEMLLKIPE 145
Query: 120 TXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH---SEYLGFENELEPIIVVKKPLDFE 176
+ D D G ++ +Y + P H + + + P +V+ K LD E
Sbjct: 146 STQPGTVFPLKIAQDFDI-GSNTVQNYTISPNSHFHVATHNRGDGRKYPELVLDKALDRE 204
Query: 177 TVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTT 236
++ L D G+PP TT+++ VLD +D P+F Y +P+++ + +
Sbjct: 205 ERPELSLTLTALDGGAPPRSGTTTIRIVVLDNNDNAPEFLQSFYEVQVPENSPLNSLVVV 264
Query: 237 SPGPISAADQDLGINAPLQYS-STGDH-KQLIVVNKDTGQVAATKQLIAELDPSVTIVLK 294
+SA D D G + Y+ GD Q V+++ T ++ + L E P + +
Sbjct: 265 ----VSARDLDAGAYGSVAYALFQGDEVTQPFVIDEKTAEIRLKRALDFEATPYYNVEIV 320
Query: 295 ATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVP 354
AT D T+ + T S+ E A P +V+ +
Sbjct: 321 AT--DGGGLSGKCTVAIEVVDVNDNAP-----ELTMSTLSSPTPENA-PETVVAVFSVSD 372
Query: 355 QNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSIS---N 411
++ + +D FL K + N ++ +R+LD E+ + Y + VTD +
Sbjct: 373 PDSGDNGRMICSIQNDLPFLLKPTLKNFYTLVTQRTLDRESQAEYNITITVTDMGTPRLK 432
Query: 412 DTASINISVEDVNEWEPRFRHPQY 435
+I + V DVN+ P F Y
Sbjct: 433 TEHNITVLVSDVNDNAPAFTQTSY 456
Score = 79.8 bits (188), Expect = 4e-14
Identities = 115/477 (24%), Positives = 176/477 (36%), Gaps = 29/477 (6%)
Query: 57 LTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVR 116
L L +ALDREE+ + + + S + + V D NDNAP++ + Y V+
Sbjct: 195 LVLDKALDREER---PELSLTLTALDGGAPPRSGTTTIRIVVLDNNDNAPEFLQSFYEVQ 251
Query: 117 VSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFE 176
V E D D G + ++ YA+ G +E I +K+ LDFE
Sbjct: 252 VPENSPLNSLVVVVSARDLDA-GAYGSVAYALFQGDEVTQPFVIDEKTAEIRLKRALDFE 310
Query: 177 TVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTT 236
+ +++ D G L T+ + V+D +D P+ T ++ P++A E T
Sbjct: 311 ATPYYNVEIVATDGGG--LSGKCTVAIEVVDVNDNAPELTMSTLSSPTPENAPE-----T 363
Query: 237 SPGPISAADQDLGINAPLQYSSTGDHKQLIVVN-KDTGQVAATKQLIAELDPSVTIVLKA 295
S +D D G N + S D L+ K+ + + L E I +
Sbjct: 364 VVAVFSVSDPDSGDNGRMICSIQNDLPFLLKPTLKNFYTLVTQRTLDRESQAEYNITITV 423
Query: 296 TQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASP----GSVLLTLT 351
T + P L T FTQ Y+ V E SP GSV T
Sbjct: 424 TDMGTP---RLKTEHNITVLVSDVNDNAPA--FTQTSYTLFVRENNSPALHIGSVSATDR 478
Query: 352 TVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTDSIS 410
N + S L +IN + G + RSLDYE + ++V TD S
Sbjct: 479 DSGTNAQVTYSLLPPQNPHLRLASLVSINADNGHLFALRSLDYEALQAFEFRVGATDRGS 538
Query: 411 ---NDTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGDAGT 467
+ A + + V D N+ P +P VA DGD+G
Sbjct: 539 PALSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVTKVVAVDGDSGQ 598
Query: 468 LA-LS---LAGQHARMFYINASGDLFLREEAIGNLNSSSLHLVATAIDSGIPPRQTS 520
A LS L +F + A + +++ LV D+G PPR +
Sbjct: 599 NAWLSYQLLKATEPGLFSMWAHNGEVRTARLLSERDAAKHRLVVLVKDNGEPPRSAT 655
Score = 79.4 bits (187), Expect = 5e-14
Identities = 88/308 (28%), Positives = 133/308 (43%), Gaps = 29/308 (9%)
Query: 19 SIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLL---RALDREEKIGPSNVY 75
+++ SV+ S D G + +Q + + P KN L R LDRE + N+
Sbjct: 363 TVVAVFSVSDPDSGDNGRMICSIQNDLPFL-LKPTLKNFYTLVTQRTLDRESQ-AEYNIT 420
Query: 76 VNVRC--DRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXS 133
+ V R T+ + + VS DVNDNAP + Y + V E +
Sbjct: 421 ITVTDMGTPRLKTEHNITVLVS----DVNDNAPAFTQTSYTLFVRENNSPALHIGSVSAT 476
Query: 134 DRDQPGPHSALHYAVLP--GPHSEYLGFE--NELEPIIVVKKPLDFETVNNFTIKLRVQD 189
DRD G ++ + Y++LP PH N + + LD+E + F ++ D
Sbjct: 477 DRDS-GTNAQVTYSLLPPQNPHLRLASLVSINADNGHLFALRSLDYEALQAFEFRVGATD 535
Query: 190 QGSPPLYSDTTLQVTVLDADDQNPKFTY------EHYTALLPDDAEEGTFLTTSPGPISA 243
+GSP L S+ ++V VLDA+D +P Y T L+P AE G +T + A
Sbjct: 536 RGSPALSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVT----KVVA 591
Query: 244 ADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPSV-TIVLKATQVDNP 301
D D G NA L Y L + G+V T +L++E D + +V+ P
Sbjct: 592 VDGDSGQNAWLSYQLLKATEPGLFSMWAHNGEV-RTARLLSERDAAKHRLVVLVKDNGEP 650
Query: 302 DRYALATL 309
R A ATL
Sbjct: 651 PRSATATL 658
>BC130333-1|AAI30334.1| 793|Homo sapiens protocadherin beta 7
protein.
Length = 793
Score = 85.4 bits (202), Expect = 8e-16
Identities = 93/441 (21%), Positives = 185/441 (41%), Gaps = 31/441 (7%)
Query: 9 FFISEDTPIGSIIGTLSVNGDPSEDLGDITLR----LQEKGAAVGIVPG-SKNLTLLRAL 63
+F++E+T G+ + L+ D +G++ R + ++ + ++ + +L L L
Sbjct: 33 YFVAEETERGTFLTNLAK--DLGLGVGELRARGTRIVSDQNMQILLLSSLTGDLLLNEKL 90
Query: 64 DREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXX 123
DREE GP V + P + + V D+ND+AP + ++++ E+
Sbjct: 91 DREELCGPREPCVLPF--QLLLEKPFQIFRAELWVRDINDHAPVFLDREISLKILESTTP 148
Query: 124 XXXXXXXXXSDRDQPGPHSALHYAVLPGPH---SEYLGFENELEPIIVVKKPLDFETVNN 180
D D G +S +Y + P + + + E + P +V+ + LD E +
Sbjct: 149 GAAFLLESAQDSDV-GTNSLSNYTISPNAYFHINVHDSGEGNIYPELVLNQVLDREEIPE 207
Query: 181 FTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGP 240
F++ L D GSPP +++ VLD +D P F Y +P+++ G+ + +
Sbjct: 208 FSLTLTALDGGSPPRSGTALVRILVLDVNDNAPDFVRSLYKVQVPENSPVGSMVVS---- 263
Query: 241 ISAADQDLGINAPLQYSSTGDHKQLI---VVNKDTGQVAATKQLIAELDPSVTIVLKATQ 297
+SA D D G N + Y+ + ++++ +N +G + QL E + T+ ++A
Sbjct: 264 VSARDLDTGSNGEIAYAFSYATERILKTFQINPTSGSLHLKAQLDYEAIQTYTLTIQAK- 322
Query: 298 VDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNT 357
D T+ + ++ ++E SP +V+ +++
Sbjct: 323 -DGGGLSGKCTVVVDVTDINDNRP-----ELLLSSLTSPIAEN-SPETVVAVFRIRDRDS 375
Query: 358 EFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSIS---NDTA 414
+ D F+ K ++ N ++ + LD E + Y + VTD +
Sbjct: 376 GNNGKTVCSIQDDLPFILKPSVENFYTLVTEKPLDRERNTEYNITITVTDLGTPRLKTEH 435
Query: 415 SINISVEDVNEWEPRFRHPQY 435
+I + V DVN+ P F Y
Sbjct: 436 NITVLVSDVNDNAPAFTQTSY 456
Score = 74.5 bits (175), Expect = 1e-12
Identities = 105/441 (23%), Positives = 159/441 (36%), Gaps = 27/441 (6%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
V + V DVNDNAP + + Y V+V E D D G + + YA
Sbjct: 228 VRILVLDVNDNAPDFVRSLYKVQVPENSPVGSMVVSVSARDLDT-GSNGEIAYAFSYATE 286
Query: 154 SEYLGFE-NELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQN 212
F+ N + +K LD+E + +T+ ++ +D G L T+ V V D +D
Sbjct: 287 RILKTFQINPTSGSLHLKAQLDYEAIQTYTLTIQAKDGGG--LSGKCTVVVDVTDINDNR 344
Query: 213 PKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDT 272
P+ T+ + +++ E T D+D G N S D ++ + +
Sbjct: 345 PELLLSSLTSPIAENSPE-----TVVAVFRIRDRDSGNNGKTVCSIQDDLPFILKPSVEN 399
Query: 273 GQVAAT-KQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQK 331
T K L E + I + T + P L T FTQ
Sbjct: 400 FYTLVTEKPLDRERNTEYNITITVTDLGTP---RLKTEHNITVLVSDVNDNAPA--FTQT 454
Query: 332 QYSTTVSEGASP----GSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVI 386
Y+ V E SP GSV T N + S L +IN + G +
Sbjct: 455 SYTLFVRENNSPALPIGSVSATDRDSGTNAQVIYSLLPSQDPHLPLASLVSINADNGHLF 514
Query: 387 LRRSLDYETTSNYFYQVMVTDSIS---NDTASINISVEDVNEWEPRFRHPQYEFEXXXXX 443
RSLDYE + ++V TD S + A + + V D N+ P +P
Sbjct: 515 ALRSLDYEALQAFEFRVGATDRGSPALSSEALVRVLVLDANDNSPFVLYPLQNSSAPCTE 574
Query: 444 XXXXXXXXXXXXXXXVAHDGDAGTLA-LS---LAGQHARMFYINASGDLFLREEAIGNLN 499
VA DGD+G A LS L +F + A + +
Sbjct: 575 PLPRAAEPGYLVTKVVAVDGDSGQNAWLSYQLLKATEPGLFGVWAHNGEVRTARLLSERD 634
Query: 500 SSSLHLVATAIDSGIPPRQTS 520
++ LV D+G PPR +
Sbjct: 635 AAKQRLVVLVKDNGEPPRSAT 655
Score = 74.5 bits (175), Expect = 1e-12
Identities = 70/228 (30%), Positives = 101/228 (44%), Gaps = 18/228 (7%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPG-- 151
++V V DVNDNAP + Y + V E +DRD G ++ + Y++LP
Sbjct: 437 ITVLVSDVNDNAPAFTQTSYTLFVRENNSPALPIGSVSATDRDS-GTNAQVIYSLLPSQD 495
Query: 152 PHSEYLGFE--NELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDAD 209
PH N + + LD+E + F ++ D+GSP L S+ ++V VLDA+
Sbjct: 496 PHLPLASLVSINADNGHLFALRSLDYEALQAFEFRVGATDRGSPALSSEALVRVLVLDAN 555
Query: 210 DQNPKFTY------EHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYS-STGDH 262
D +P Y T LP AE G +T + A D D G NA L Y
Sbjct: 556 DNSPFVLYPLQNSSAPCTEPLPRAAEPGYLVT----KVVAVDGDSGQNAWLSYQLLKATE 611
Query: 263 KQLIVVNKDTGQVAATKQLIAELDPS-VTIVLKATQVDNPDRYALATL 309
L V G+V T +L++E D + +V+ P R A ATL
Sbjct: 612 PGLFGVWAHNGEV-RTARLLSERDAAKQRLVVLVKDNGEPPRSATATL 658
>BC098574-1|AAH98574.1| 793|Homo sapiens protocadherin beta 7
protein.
Length = 793
Score = 85.4 bits (202), Expect = 8e-16
Identities = 93/441 (21%), Positives = 185/441 (41%), Gaps = 31/441 (7%)
Query: 9 FFISEDTPIGSIIGTLSVNGDPSEDLGDITLR----LQEKGAAVGIVPG-SKNLTLLRAL 63
+F++E+T G+ + L+ D +G++ R + ++ + ++ + +L L L
Sbjct: 33 YFVAEETERGTFLTNLAK--DLGLGVGELRARGTRIVSDQNMQILLLSSLTGDLLLNEKL 90
Query: 64 DREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXX 123
DREE GP V + P + + V D+ND+AP + ++++ E+
Sbjct: 91 DREELCGPREPCVLPF--QLLLEKPFQIFRAKLWVRDINDHAPVFLDREISLKILESTTP 148
Query: 124 XXXXXXXXXSDRDQPGPHSALHYAVLPGPH---SEYLGFENELEPIIVVKKPLDFETVNN 180
D D G +S +Y + P + + + E + P +V+ + LD E +
Sbjct: 149 GAAFLLESAQDSDV-GTNSLSNYTISPNAYFHINVHDSGEGNIYPELVLNQVLDREEIPE 207
Query: 181 FTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGP 240
F++ L D GSPP +++ VLD +D P F Y +P+++ G+ + +
Sbjct: 208 FSLTLTALDGGSPPRSGTALVRILVLDVNDNAPDFVRSLYKVQVPENSPVGSMVVS---- 263
Query: 241 ISAADQDLGINAPLQYSSTGDHKQLI---VVNKDTGQVAATKQLIAELDPSVTIVLKATQ 297
+SA D D G N + Y+ + ++++ +N +G + QL E + T+ ++A
Sbjct: 264 VSARDLDTGSNGEIAYAFSYATERILKTFQINPTSGSLHLKAQLDYEAIQTYTLTIQAK- 322
Query: 298 VDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNT 357
D T+ + ++ ++E SP +V+ +++
Sbjct: 323 -DGGGLSGKCTVVVDVTDINDNRP-----ELLLSSLTSPIAEN-SPETVVAVFRIRDRDS 375
Query: 358 EFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSIS---NDTA 414
+ D F+ K ++ N ++ + LD E + Y + VTD +
Sbjct: 376 GNNGKTVCSIQDDLPFILKPSVENFYTLVTEKPLDRERNTEYNITITVTDLGTPRLKTEH 435
Query: 415 SINISVEDVNEWEPRFRHPQY 435
+I + V DVN+ P F Y
Sbjct: 436 NITVLVSDVNDNAPAFTQTSY 456
Score = 74.5 bits (175), Expect = 1e-12
Identities = 105/441 (23%), Positives = 159/441 (36%), Gaps = 27/441 (6%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
V + V DVNDNAP + + Y V+V E D D G + + YA
Sbjct: 228 VRILVLDVNDNAPDFVRSLYKVQVPENSPVGSMVVSVSARDLDT-GSNGEIAYAFSYATE 286
Query: 154 SEYLGFE-NELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQN 212
F+ N + +K LD+E + +T+ ++ +D G L T+ V V D +D
Sbjct: 287 RILKTFQINPTSGSLHLKAQLDYEAIQTYTLTIQAKDGGG--LSGKCTVVVDVTDINDNR 344
Query: 213 PKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDT 272
P+ T+ + +++ E T D+D G N S D ++ + +
Sbjct: 345 PELLLSSLTSPIAENSPE-----TVVAVFRIRDRDSGNNGKTVCSIQDDLPFILKPSVEN 399
Query: 273 GQVAAT-KQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQK 331
T K L E + I + T + P L T FTQ
Sbjct: 400 FYTLVTEKPLDRERNTEYNITITVTDLGTP---RLKTEHNITVLVSDVNDNAPA--FTQT 454
Query: 332 QYSTTVSEGASP----GSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVI 386
Y+ V E SP GSV T N + S L +IN + G +
Sbjct: 455 SYTLFVRENNSPALPIGSVSATDRDSGTNAQVIYSLLPSQDPHLPLTSLVSINADNGHLF 514
Query: 387 LRRSLDYETTSNYFYQVMVTDSIS---NDTASINISVEDVNEWEPRFRHPQYEFEXXXXX 443
RSLDYE + ++V TD S + A + + V D N+ P +P
Sbjct: 515 ALRSLDYEALQAFEFRVGATDRGSPALSSEALVRVLVLDANDNSPFVLYPLQNSSAPCTE 574
Query: 444 XXXXXXXXXXXXXXXVAHDGDAGTLA-LS---LAGQHARMFYINASGDLFLREEAIGNLN 499
VA DGD+G A LS L +F + A + +
Sbjct: 575 PLPRAAEPGYLVTKVVAVDGDSGQNAWLSYQLLKATEPGLFGVWAHNGEVRTARLLSERD 634
Query: 500 SSSLHLVATAIDSGIPPRQTS 520
++ LV D+G PPR +
Sbjct: 635 AAKQRLVVLVKDNGEPPRSAT 655
Score = 74.5 bits (175), Expect = 1e-12
Identities = 70/228 (30%), Positives = 101/228 (44%), Gaps = 18/228 (7%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPG-- 151
++V V DVNDNAP + Y + V E +DRD G ++ + Y++LP
Sbjct: 437 ITVLVSDVNDNAPAFTQTSYTLFVRENNSPALPIGSVSATDRDS-GTNAQVIYSLLPSQD 495
Query: 152 PHSEYLGFE--NELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDAD 209
PH N + + LD+E + F ++ D+GSP L S+ ++V VLDA+
Sbjct: 496 PHLPLTSLVSINADNGHLFALRSLDYEALQAFEFRVGATDRGSPALSSEALVRVLVLDAN 555
Query: 210 DQNPKFTY------EHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYS-STGDH 262
D +P Y T LP AE G +T + A D D G NA L Y
Sbjct: 556 DNSPFVLYPLQNSSAPCTEPLPRAAEPGYLVT----KVVAVDGDSGQNAWLSYQLLKATE 611
Query: 263 KQLIVVNKDTGQVAATKQLIAELDPS-VTIVLKATQVDNPDRYALATL 309
L V G+V T +L++E D + +V+ P R A ATL
Sbjct: 612 PGLFGVWAHNGEV-RTARLLSERDAAKQRLVVLVKDNGEPPRSATATL 658
>BC003126-1|AAH03126.1| 808|Homo sapiens protocadherin alpha 2
protein.
Length = 808
Score = 85.4 bits (202), Expect = 8e-16
Identities = 109/444 (24%), Positives = 175/444 (39%), Gaps = 33/444 (7%)
Query: 9 FFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEK--GAAVGIVPGSKNLTLLRALDR 65
+ + E+ G+ +G ++ + G E+L R+ K G + + + L + +DR
Sbjct: 33 YSVPEEAKHGTFVGRIAQDLGLELEELVPRLFRVASKRHGDLLEVNLQNGILFVNSRIDR 92
Query: 66 EEKIGPS---NVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXX 122
EE G S +++V V DR P V V V V D+NDN P + +R E+
Sbjct: 93 EELCGRSAECSIHVEVIVDR-----PLQVFHVEVEVKDINDNPPIFPMTVKTIRFPESRL 147
Query: 123 XXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFE--NELEPII--VVKKPLDFETV 178
SD D G ++ L Y L +L + +EL + V+ K LD E
Sbjct: 148 LDSRFPLEGASDADI-GVNALLSYK-LSSSEFFFLDIQANDELSESLSLVLGKSLDREET 205
Query: 179 NNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSP 238
+ L D G P L + + VLD +D P F Y L ++ GT +
Sbjct: 206 AEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQSVYKVKLLENTANGTLVV--- 262
Query: 239 GPISAADQDLGINAPLQYSSTGDHKQLI----VVNKDTGQVAATKQLIAELDPSVTIVLK 294
++A+D D G N+ + YS D I ++ +G++ +L E S I +
Sbjct: 263 -KLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTKGKLDYEEAKSYEIQVT 321
Query: 295 ATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVP 354
AT P + + + S +SE AS G+V+ +T
Sbjct: 322 ATDKGTPSMSGHCKISLKLVDINDNTP-----EVSITSLSLPISENASLGTVIALITVSD 376
Query: 355 QNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSISND-- 412
+++ F N ++L +LD E+ S Y V D S
Sbjct: 377 RDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPSLW 436
Query: 413 -TASINISVEDVNEWEPRFRHPQY 435
T S++I V DVN+ P F P+Y
Sbjct: 437 ATTSVSIEVADVNDNAPAFAQPEY 460
Score = 83.0 bits (196), Expect = 4e-15
Identities = 86/393 (21%), Positives = 167/393 (42%), Gaps = 26/393 (6%)
Query: 54 SKNLTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPY 113
S +L L ++LDREE + + V + T + + ++V DVNDN P + + Y
Sbjct: 191 SLSLVLGKSLDREETAEVNLLLVATDGGKPELTG---TVQILIKVLDVNDNEPTFAQSVY 247
Query: 114 AVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPI---IVVK 170
V++ E SD D+ GP+S + Y+ L S + + ++PI I K
Sbjct: 248 KVKLLENTANGTLVVKLNASDADE-GPNSEIVYS-LGSDVSSTIQTKFTIDPISGEIRTK 305
Query: 171 KPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEE 230
LD+E ++ I++ D+G+P + + + ++D +D P+ + + + ++A
Sbjct: 306 GKLDYEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASL 365
Query: 231 GTFLTTSPGPISAADQDLGINAPLQYSSTGDHK-QLIVVNKDTGQVAATKQLIAELDPSV 289
GT + I+ +D+D G N + S T +L+ K+ + L E +
Sbjct: 366 GTVIAL----ITVSDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAY 421
Query: 290 TIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLT 349
+V+ A +P +A ++ F Q +Y+ V E PG + T
Sbjct: 422 ELVVTARDGGSPSLWATTSVSIEVADVNDNAPA-----FAQPEYTVFVKENNPPGCHIFT 476
Query: 350 LTT----VPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVM 404
++ +N S ++ V +R+ +++ +G+V + LD+E +QV
Sbjct: 477 VSAWDADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVS 536
Query: 405 VTDS---ISNDTASINISVEDVNEWEPRFRHPQ 434
D+ ++ + V D N+ P P+
Sbjct: 537 ARDAGVPPLGSNVTLQVFVLDENDNAPALLAPR 569
Score = 70.5 bits (165), Expect = 2e-11
Identities = 88/318 (27%), Positives = 125/318 (39%), Gaps = 30/318 (9%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKN---LTLLRALDREE 67
ISE+ +G++I ++V+ S G +T L +V KN L L ALDRE
Sbjct: 359 ISENASLGTVIALITVSDRDSGTNGHVTCSLTPH-VPFKLVSTFKNYYSLVLDSALDRES 417
Query: 68 KIGPSNVYVNVRCDRRRTTDPSF--VIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXX 125
+ + V R PS VS+ V DVNDNAP + Y V V E
Sbjct: 418 -VSAYELVVTARDGG----SPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGC 472
Query: 126 XXXXXXXSDRDQPG----PHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNF 181
D D +S + V S Y+ E + ++ PLD E V
Sbjct: 473 HIFTVSAWDADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQ-PLDHEEVELL 531
Query: 182 TIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEH-------YTALLPDDAEEGTFL 234
++ +D G PPL S+ TLQV VLD +D P + L+P G +
Sbjct: 532 QFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVV 591
Query: 235 TTSPGPISAADQDLGINAPLQYS---STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTI 291
+ A D D G NA L Y TG + V TG+++ T+ L P +
Sbjct: 592 ----AKVRAVDADSGYNAWLSYELQLGTGSARIPFRVGLYTGEISTTRALDEADSPRHRL 647
Query: 292 VLKATQVDNPDRYALATL 309
++ P A AT+
Sbjct: 648 LVLVKDHGEPALTATATV 665
Score = 68.9 bits (161), Expect = 7e-11
Identities = 55/209 (26%), Positives = 93/209 (44%), Gaps = 11/209 (5%)
Query: 50 IVPGSKNLTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWE 109
I P S + LD EE + + V + T S +S+++ D+NDN P+
Sbjct: 295 IDPISGEIRTKGKLDYEEA---KSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVS 351
Query: 110 GAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPG-PHSEYLGFENELEPIIV 168
++ +SE SDRD G + + ++ P P F+N +V
Sbjct: 352 ITSLSLPISENASLGTVIALITVSDRDS-GTNGHVTCSLTPHVPFKLVSTFKNYYS--LV 408
Query: 169 VKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDA 228
+ LD E+V+ + + + +D GSP L++ T++ + V D +D P F YT + ++
Sbjct: 409 LDSALDRESVSAYELVVTARDGGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENN 468
Query: 229 EEGTFLTTSPGPISAADQDLGINAPLQYS 257
G + T +SA D D NA + YS
Sbjct: 469 PPGCHIFT----VSAWDADAQENALVSYS 493
>AK222678-1|BAD96398.1| 793|Homo sapiens protocadherin beta 7
precursor variant protein.
Length = 793
Score = 85.4 bits (202), Expect = 8e-16
Identities = 93/441 (21%), Positives = 185/441 (41%), Gaps = 31/441 (7%)
Query: 9 FFISEDTPIGSIIGTLSVNGDPSEDLGDITLR----LQEKGAAVGIVPG-SKNLTLLRAL 63
+F++E+T G+ + L+ D +G++ R + ++ + ++ + +L L L
Sbjct: 33 YFVAEETERGTFLTNLAK--DLGLGVGELRARGTRIVSDQNMQILLLSSLTGDLLLNEKL 90
Query: 64 DREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXX 123
DREE GP V + P + + V D+ND+AP + ++++ E+
Sbjct: 91 DREELCGPREPCVLPF--QLLLEKPFQIFRAELWVRDINDHAPVFLDREISLKILESTTP 148
Query: 124 XXXXXXXXXSDRDQPGPHSALHYAVLPGPH---SEYLGFENELEPIIVVKKPLDFETVNN 180
D D G +S +Y + P + + + E + P +V+ + LD E +
Sbjct: 149 GAAFLLESAQDSDV-GTNSLSNYTISPNAYFHINVHDSGEGNIYPELVLNQVLDREEIPE 207
Query: 181 FTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGP 240
F++ L D GSPP +++ VLD +D P F Y +P+++ G+ + +
Sbjct: 208 FSLTLTALDGGSPPRSGTALVRILVLDVNDNAPDFVRSLYKVQVPENSPVGSMVVS---- 263
Query: 241 ISAADQDLGINAPLQYSSTGDHKQLI---VVNKDTGQVAATKQLIAELDPSVTIVLKATQ 297
+SA D D G N + Y+ + ++++ +N +G + QL E + T+ ++A
Sbjct: 264 VSARDLDTGSNGEIAYAFSYATERILKTFQINPTSGSLHLKAQLDYEAIQTYTLTIQAK- 322
Query: 298 VDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNT 357
D T+ + ++ ++E SP +V+ +++
Sbjct: 323 -DGGGLSGKCTVVVDVTDINDNRP-----ELLLSSLTSPIAEN-SPETVVAVFRIRDRDS 375
Query: 358 EFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSIS---NDTA 414
+ D F+ K ++ N ++ + LD E + Y + VTD +
Sbjct: 376 GNNGKTVCSIQDDLPFILKPSVENFYTLVTEKPLDRERNTEYNITITVTDLGTPRLKTEH 435
Query: 415 SINISVEDVNEWEPRFRHPQY 435
+I + V DVN+ P F Y
Sbjct: 436 NITVLVSDVNDNAPAFTQTSY 456
Score = 74.5 bits (175), Expect = 1e-12
Identities = 105/441 (23%), Positives = 159/441 (36%), Gaps = 27/441 (6%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
V + V DVNDNAP + + Y V+V E D D G + + YA
Sbjct: 228 VRILVLDVNDNAPDFVRSLYKVQVPENSPVGSMVVSVSARDLDT-GSNGEIAYAFSYATE 286
Query: 154 SEYLGFE-NELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQN 212
F+ N + +K LD+E + +T+ ++ +D G L T+ V V D +D
Sbjct: 287 RILKTFQINPTSGSLHLKAQLDYEAIQTYTLTIQAKDGGG--LSGKCTVVVDVTDINDNR 344
Query: 213 PKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDT 272
P+ T+ + +++ E T D+D G N S D ++ + +
Sbjct: 345 PELLLSSLTSPIAENSPE-----TVVAVFRIRDRDSGNNGKTVCSIQDDLPFILKPSVEN 399
Query: 273 GQVAAT-KQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQK 331
T K L E + I + T + P L T FTQ
Sbjct: 400 FYTLVTEKPLDRERNTEYNITITVTDLGTP---RLKTEHNITVLVSDVNDNAPA--FTQT 454
Query: 332 QYSTTVSEGASP----GSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVI 386
Y+ V E SP GSV T N + S L +IN + G +
Sbjct: 455 SYTLFVRENNSPALPIGSVSATDRDSGTNAQVIYSLLPSQDPHLPLASLVSINADNGHLF 514
Query: 387 LRRSLDYETTSNYFYQVMVTDSIS---NDTASINISVEDVNEWEPRFRHPQYEFEXXXXX 443
RSLDYE + ++V TD S + A + + V D N+ P +P
Sbjct: 515 ALRSLDYEALQAFEFRVGATDRGSPALSSEALVRVLVLDANDNSPFVLYPLQNSSAPCTE 574
Query: 444 XXXXXXXXXXXXXXXVAHDGDAGTLA-LS---LAGQHARMFYINASGDLFLREEAIGNLN 499
VA DGD+G A LS L +F + A + +
Sbjct: 575 PLPRAAEPGYLVTKVVAVDGDSGQNAWLSYQLLKATEPGLFGVWAHNGEVRTARLLSERD 634
Query: 500 SSSLHLVATAIDSGIPPRQTS 520
++ LV D+G PPR +
Sbjct: 635 AAKQRLVVLVKDNGEPPRSAT 655
Score = 74.5 bits (175), Expect = 1e-12
Identities = 70/228 (30%), Positives = 101/228 (44%), Gaps = 18/228 (7%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPG-- 151
++V V DVNDNAP + Y + V E +DRD G ++ + Y++LP
Sbjct: 437 ITVLVSDVNDNAPAFTQTSYTLFVRENNSPALPIGSVSATDRDS-GTNAQVIYSLLPSQD 495
Query: 152 PHSEYLGFE--NELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDAD 209
PH N + + LD+E + F ++ D+GSP L S+ ++V VLDA+
Sbjct: 496 PHLPLASLVSINADNGHLFALRSLDYEALQAFEFRVGATDRGSPALSSEALVRVLVLDAN 555
Query: 210 DQNPKFTY------EHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYS-STGDH 262
D +P Y T LP AE G +T + A D D G NA L Y
Sbjct: 556 DNSPFVLYPLQNSSAPCTEPLPRAAEPGYLVT----KVVAVDGDSGQNAWLSYQLLKATE 611
Query: 263 KQLIVVNKDTGQVAATKQLIAELDPS-VTIVLKATQVDNPDRYALATL 309
L V G+V T +L++E D + +V+ P R A ATL
Sbjct: 612 PGLFGVWAHNGEV-RTARLLSERDAAKQRLVVLVKDNGEPPRSATATL 658
>AJ007609-1|CAC22256.1| 949|Homo sapiens protocadherin alpha 11
protein.
Length = 949
Score = 85.4 bits (202), Expect = 8e-16
Identities = 102/445 (22%), Positives = 181/445 (40%), Gaps = 36/445 (8%)
Query: 9 FFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEK--GAAVGIVPGSKNLTLLRALDR 65
+ +SE+ G+ +G ++ + G +L R+ K G + + + L + +DR
Sbjct: 33 YSVSEEAKHGTFVGRIAQDLGLELAELVQRLFRVASKTHGDLLEVNLQNGILFVNSRIDR 92
Query: 66 EEKIGPS---NVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXX 122
EE G S ++++ V DR P V V+V V D+NDN P + + ++E+
Sbjct: 93 EELCGQSAECSIHLEVIVDR-----PLQVFHVNVEVKDINDNPPVFSLREQKLLIAESKQ 147
Query: 123 XXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFEN-----ELEPI-IVVKKPLDFE 176
SD D ++ L Y + +EY ++ +++ + +++KK LD E
Sbjct: 148 SDSRFPLEGASDADIE-ENALLTYRL---SKNEYFSLDSPTNGKQIKRLSLILKKSLDRE 203
Query: 177 TVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTT 236
+ L D G P L L V VLD +D +P+F Y L ++A + T +
Sbjct: 204 KTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDPEFDKSEYKVSLMENAAKETLVL- 262
Query: 237 SPGPISAADQDLGINAPLQYSSTG---DHKQLIVVNKDTGQVAATKQLIAELDPSVTIVL 293
++A D+D G+N + YS + + L ++++ G+V L E + I +
Sbjct: 263 ---KLNATDRDEGVNGEVTYSLMSIKPNGRHLFTLDQNNGEVRVNGTLDYEENKFYKIEV 319
Query: 294 KATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTV 353
+AT P T+ + S V E A P +V+ ++
Sbjct: 320 QATDKGTPPMAGHCTVWVEILDTNDNSP-----EVAVTSLSLPVREDAQPSTVIALISVS 374
Query: 354 PQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSISND- 412
+++ F N ++L +LD E Y V D S
Sbjct: 375 DRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAYELVVTARDGGSPSL 434
Query: 413 --TASINISVEDVNEWEPRFRHPQY 435
TA +++ V DVN+ P F P+Y
Sbjct: 435 WATARVSVEVADVNDNAPAFAQPEY 459
Score = 85.4 bits (202), Expect = 8e-16
Identities = 81/360 (22%), Positives = 160/360 (44%), Gaps = 20/360 (5%)
Query: 56 NLTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAV 115
+L L ++LDRE K N+ + + + + + + V+V DVNDN P+++ + Y V
Sbjct: 193 SLILKKSLDRE-KTPELNLLLTATDGGK--PELTGTVRLLVQVLDVNDNDPEFDKSEYKV 249
Query: 116 RVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLP-GPHSEYLGFENELEPIIVVKKPLD 174
+ E +DRD+ G + + Y+++ P+ +L ++ + V LD
Sbjct: 250 SLMENAAKETLVLKLNATDRDE-GVNGEVTYSLMSIKPNGRHLFTLDQNNGEVRVNGTLD 308
Query: 175 FETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFL 234
+E + I+++ D+G+PP+ T+ V +LD +D +P+ + + +DA+ T +
Sbjct: 309 YEENKFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPVREDAQPSTVI 368
Query: 235 TTSPGPISAADQDLGINAPLQYSSTGDHK-QLIVVNKDTGQVAATKQLIAELDPSVTIVL 293
IS +D+D G+N + S T +L+ K+ + L E + +V+
Sbjct: 369 AL----ISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAYELVV 424
Query: 294 KATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTT- 352
A +P +A A + F Q +Y+ V E PG + T++
Sbjct: 425 TARDGGSPSLWATARVSVEVADVNDNAPA-----FAQPEYTVFVKENNPPGCHIFTVSAR 479
Query: 353 ---VPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTDS 408
+N S ++ + DR+ +++ +G+V + LD+E +QV D+
Sbjct: 480 DADAQENALVSYSLVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 539
Score = 64.5 bits (150), Expect = 2e-09
Identities = 87/320 (27%), Positives = 126/320 (39%), Gaps = 34/320 (10%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKN---LTLLRALDREE 67
+ ED ++I +SV+ S G +T L +V KN L L ALDRE
Sbjct: 358 VREDAQPSTVIALISVSDRDSGVNGQVTCSLTPH-VPFKLVSTFKNYYSLVLDSALDRE- 415
Query: 68 KIGPSNVYV-NVRCDRRRTTDPSF--VIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXX 124
NV+ + R PS VSV V DVNDNAP + Y V V E
Sbjct: 416 -----NVWAYELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPG 470
Query: 125 XXXXXXXXSDRDQPGPHSALHYAVLP---GPH--SEYLGFENELEPIIVVKKPLDFETVN 179
D D ++ + Y+++ G S Y+ E + ++ PLD E +
Sbjct: 471 CHIFTVSARDADAQ-ENALVSYSLVERRLGDRALSSYVSVHAESGKVYALQ-PLDHEELE 528
Query: 180 NFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEH-------YTALLPDDAEEGT 232
++ +D G PPL S+ TLQV VLD +D P L+P G
Sbjct: 529 LLQFQVSARDAGVPPLSSNVTLQVFVLDENDNAPALLATQAGSAGGAVNKLVPRSVGAGH 588
Query: 233 FLTTSPGPISAADQDLGINAPLQYS---STGDHKQLIVVNKDTGQVAATKQLIAELDPSV 289
+ + A D D G NA L Y + G + V TG+++ T+ L P
Sbjct: 589 VV----AKVRAVDADSGYNAWLSYELQPAAGGSRIPFRVGLYTGEISTTRALDEADSPRH 644
Query: 290 TIVLKATQVDNPDRYALATL 309
+++ P A AT+
Sbjct: 645 RLLVLVKDHGEPALTATATV 664
>AF152480-1|AAD43741.1| 824|Homo sapiens protocadherin alpha 2
short form protein protein.
Length = 824
Score = 85.4 bits (202), Expect = 8e-16
Identities = 109/444 (24%), Positives = 175/444 (39%), Gaps = 33/444 (7%)
Query: 9 FFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEK--GAAVGIVPGSKNLTLLRALDR 65
+ + E+ G+ +G ++ + G E+L R+ K G + + + L + +DR
Sbjct: 33 YSVPEEAKHGTFVGRIAQDLGLELEELVPRLFRVASKRHGDLLEVNLQNGILFVNSRIDR 92
Query: 66 EEKIGPS---NVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXX 122
EE G S +++V V DR P V V V V D+NDN P + +R E+
Sbjct: 93 EELCGRSAECSIHVEVIVDR-----PLQVFHVEVEVKDINDNPPIFPMTVKTIRFPESRL 147
Query: 123 XXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFE--NELEPII--VVKKPLDFETV 178
SD D G ++ L Y L +L + +EL + V+ K LD E
Sbjct: 148 LDSRFPLEGASDADI-GVNALLSYK-LSSSEFFFLDIQANDELSESLSLVLGKSLDREET 205
Query: 179 NNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSP 238
+ L D G P L + + VLD +D P F Y L ++ GT +
Sbjct: 206 AEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQSVYKVKLLENTANGTLVV--- 262
Query: 239 GPISAADQDLGINAPLQYSSTGDHKQLI----VVNKDTGQVAATKQLIAELDPSVTIVLK 294
++A+D D G N+ + YS D I ++ +G++ +L E S I +
Sbjct: 263 -KLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTKGKLDYEEAKSYEIQVT 321
Query: 295 ATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVP 354
AT P + + + S +SE AS G+V+ +T
Sbjct: 322 ATDKGTPSMSGHCKISLKLVDINDNTP-----EVSITSLSLPISENASLGTVIALITVSD 376
Query: 355 QNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSISND-- 412
+++ F N ++L +LD E+ S Y V D S
Sbjct: 377 RDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPSLW 436
Query: 413 -TASINISVEDVNEWEPRFRHPQY 435
T S++I V DVN+ P F P+Y
Sbjct: 437 ATTSVSIEVADVNDNAPAFAQPEY 460
Score = 83.0 bits (196), Expect = 4e-15
Identities = 86/393 (21%), Positives = 167/393 (42%), Gaps = 26/393 (6%)
Query: 54 SKNLTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPY 113
S +L L ++LDREE + + V + T + + ++V DVNDN P + + Y
Sbjct: 191 SLSLVLGKSLDREETAEVNLLLVATDGGKPELTG---TVQILIKVLDVNDNEPTFAQSVY 247
Query: 114 AVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPI---IVVK 170
V++ E SD D+ GP+S + Y+ L S + + ++PI I K
Sbjct: 248 KVKLLENTANGTLVVKLNASDADE-GPNSEIVYS-LGSDVSSTIQTKFTIDPISGEIRTK 305
Query: 171 KPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEE 230
LD+E ++ I++ D+G+P + + + ++D +D P+ + + + ++A
Sbjct: 306 GKLDYEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASL 365
Query: 231 GTFLTTSPGPISAADQDLGINAPLQYSSTGDHK-QLIVVNKDTGQVAATKQLIAELDPSV 289
GT + I+ +D+D G N + S T +L+ K+ + L E +
Sbjct: 366 GTVIAL----ITVSDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAY 421
Query: 290 TIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLT 349
+V+ A +P +A ++ F Q +Y+ V E PG + T
Sbjct: 422 ELVVTARDGGSPSLWATTSVSIEVADVNDNAPA-----FAQPEYTVFVKENNPPGCHIFT 476
Query: 350 LTT----VPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVM 404
++ +N S ++ V +R+ +++ +G+V + LD+E +QV
Sbjct: 477 VSAWDADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVS 536
Query: 405 VTDS---ISNDTASINISVEDVNEWEPRFRHPQ 434
D+ ++ + V D N+ P P+
Sbjct: 537 ARDAGVPPLGSNVTLQVFVLDENDNAPALLAPR 569
Score = 70.5 bits (165), Expect = 2e-11
Identities = 88/318 (27%), Positives = 125/318 (39%), Gaps = 30/318 (9%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKN---LTLLRALDREE 67
ISE+ +G++I ++V+ S G +T L +V KN L L ALDRE
Sbjct: 359 ISENASLGTVIALITVSDRDSGTNGHVTCSLTPH-VPFKLVSTFKNYYSLVLDSALDRES 417
Query: 68 KIGPSNVYVNVRCDRRRTTDPSF--VIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXX 125
+ + V R PS VS+ V DVNDNAP + Y V V E
Sbjct: 418 -VSAYELVVTARDGG----SPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGC 472
Query: 126 XXXXXXXSDRDQPG----PHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNF 181
D D +S + V S Y+ E + ++ PLD E V
Sbjct: 473 HIFTVSAWDADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQ-PLDHEEVELL 531
Query: 182 TIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEH-------YTALLPDDAEEGTFL 234
++ +D G PPL S+ TLQV VLD +D P + L+P G +
Sbjct: 532 QFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVV 591
Query: 235 TTSPGPISAADQDLGINAPLQYS---STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTI 291
+ A D D G NA L Y TG + V TG+++ T+ L P +
Sbjct: 592 ----AKVRAVDADSGYNAWLSYELQLGTGSARIPFRVGLYTGEISTTRALDEADSPRHRL 647
Query: 292 VLKATQVDNPDRYALATL 309
++ P A AT+
Sbjct: 648 LVLVKDHGEPALTATATV 665
Score = 68.9 bits (161), Expect = 7e-11
Identities = 55/209 (26%), Positives = 93/209 (44%), Gaps = 11/209 (5%)
Query: 50 IVPGSKNLTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWE 109
I P S + LD EE + + V + T S +S+++ D+NDN P+
Sbjct: 295 IDPISGEIRTKGKLDYEEA---KSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVS 351
Query: 110 GAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPG-PHSEYLGFENELEPIIV 168
++ +SE SDRD G + + ++ P P F+N +V
Sbjct: 352 ITSLSLPISENASLGTVIALITVSDRDS-GTNGHVTCSLTPHVPFKLVSTFKNYYS--LV 408
Query: 169 VKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDA 228
+ LD E+V+ + + + +D GSP L++ T++ + V D +D P F YT + ++
Sbjct: 409 LDSALDRESVSAYELVVTARDGGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENN 468
Query: 229 EEGTFLTTSPGPISAADQDLGINAPLQYS 257
G + T +SA D D NA + YS
Sbjct: 469 PPGCHIFT----VSAWDADAQENALVSYS 493
>AF152476-1|AAD43737.1| 810|Homo sapiens protocadherin alpha 11
short form protein protein.
Length = 810
Score = 85.4 bits (202), Expect = 8e-16
Identities = 102/445 (22%), Positives = 181/445 (40%), Gaps = 36/445 (8%)
Query: 9 FFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEK--GAAVGIVPGSKNLTLLRALDR 65
+ +SE+ G+ +G ++ + G +L R+ K G + + + L + +DR
Sbjct: 33 YSVSEEAKHGTFVGRIAQDLGLELAELVQRLFRVASKTHGDLLEVNLQNGILFVNSRIDR 92
Query: 66 EEKIGPS---NVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXX 122
EE G S ++++ V DR P V V+V V D+NDN P + + ++E+
Sbjct: 93 EELCGQSAECSIHLEVIVDR-----PLQVFHVNVEVKDINDNPPVFSLREQKLLIAESKQ 147
Query: 123 XXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFEN-----ELEPI-IVVKKPLDFE 176
SD D ++ L Y + +EY ++ +++ + +++KK LD E
Sbjct: 148 SDSRFPLEGASDADIE-ENALLTYRL---SKNEYFSLDSPTNGKQIKRLSLILKKSLDRE 203
Query: 177 TVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTT 236
+ L D G P L L V VLD +D +P+F Y L ++A + T +
Sbjct: 204 KTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDPEFDKSEYKVSLMENAAKETLVL- 262
Query: 237 SPGPISAADQDLGINAPLQYSSTG---DHKQLIVVNKDTGQVAATKQLIAELDPSVTIVL 293
++A D+D G+N + YS + + L ++++ G+V L E + I +
Sbjct: 263 ---KLNATDRDEGVNGEVTYSLMSIKPNGRHLFTLDQNNGEVRVNGTLDYEENKFYKIEV 319
Query: 294 KATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTV 353
+AT P T+ + S V E A P +V+ ++
Sbjct: 320 QATDKGTPPMAGHCTVWVEILDTNDNSP-----EVAVTSLSLPVREDAQPSTVIALISVS 374
Query: 354 PQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSISND- 412
+++ F N ++L +LD E Y V D S
Sbjct: 375 DRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAYELVVTARDGGSPSL 434
Query: 413 --TASINISVEDVNEWEPRFRHPQY 435
TA +++ V DVN+ P F P+Y
Sbjct: 435 WATARVSVEVADVNDNAPAFAQPEY 459
Score = 85.4 bits (202), Expect = 8e-16
Identities = 81/360 (22%), Positives = 160/360 (44%), Gaps = 20/360 (5%)
Query: 56 NLTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAV 115
+L L ++LDRE K N+ + + + + + + V+V DVNDN P+++ + Y V
Sbjct: 193 SLILKKSLDRE-KTPELNLLLTATDGGK--PELTGTVRLLVQVLDVNDNDPEFDKSEYKV 249
Query: 116 RVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLP-GPHSEYLGFENELEPIIVVKKPLD 174
+ E +DRD+ G + + Y+++ P+ +L ++ + V LD
Sbjct: 250 SLMENAAKETLVLKLNATDRDE-GVNGEVTYSLMSIKPNGRHLFTLDQNNGEVRVNGTLD 308
Query: 175 FETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFL 234
+E + I+++ D+G+PP+ T+ V +LD +D +P+ + + +DA+ T +
Sbjct: 309 YEENKFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPVREDAQPSTVI 368
Query: 235 TTSPGPISAADQDLGINAPLQYSSTGDHK-QLIVVNKDTGQVAATKQLIAELDPSVTIVL 293
IS +D+D G+N + S T +L+ K+ + L E + +V+
Sbjct: 369 AL----ISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAYELVV 424
Query: 294 KATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTT- 352
A +P +A A + F Q +Y+ V E PG + T++
Sbjct: 425 TARDGGSPSLWATARVSVEVADVNDNAPA-----FAQPEYTVFVKENNPPGCHIFTVSAR 479
Query: 353 ---VPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTDS 408
+N S ++ + DR+ +++ +G+V + LD+E +QV D+
Sbjct: 480 DADAQENALVSYSLVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 539
Score = 64.5 bits (150), Expect = 2e-09
Identities = 87/320 (27%), Positives = 126/320 (39%), Gaps = 34/320 (10%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKN---LTLLRALDREE 67
+ ED ++I +SV+ S G +T L +V KN L L ALDRE
Sbjct: 358 VREDAQPSTVIALISVSDRDSGVNGQVTCSLTPH-VPFKLVSTFKNYYSLVLDSALDRE- 415
Query: 68 KIGPSNVYV-NVRCDRRRTTDPSF--VIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXX 124
NV+ + R PS VSV V DVNDNAP + Y V V E
Sbjct: 416 -----NVWAYELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPG 470
Query: 125 XXXXXXXXSDRDQPGPHSALHYAVLP---GPH--SEYLGFENELEPIIVVKKPLDFETVN 179
D D ++ + Y+++ G S Y+ E + ++ PLD E +
Sbjct: 471 CHIFTVSARDADAQ-ENALVSYSLVERRLGDRALSSYVSVHAESGKVYALQ-PLDHEELE 528
Query: 180 NFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEH-------YTALLPDDAEEGT 232
++ +D G PPL S+ TLQV VLD +D P L+P G
Sbjct: 529 LLQFQVSARDAGVPPLSSNVTLQVFVLDENDNAPALLATQAGSAGGAVNKLVPRSVGAGH 588
Query: 233 FLTTSPGPISAADQDLGINAPLQYS---STGDHKQLIVVNKDTGQVAATKQLIAELDPSV 289
+ + A D D G NA L Y + G + V TG+++ T+ L P
Sbjct: 589 VV----AKVRAVDADSGYNAWLSYELQPAAGGSRIPFRVGLYTGEISTTRALDEADSPRH 644
Query: 290 TIVLKATQVDNPDRYALATL 309
+++ P A AT+
Sbjct: 645 RLLVLVKDHGEPALTATATV 664
>AF152310-1|AAD43704.1| 948|Homo sapiens protocadherin alpha 2
protein.
Length = 948
Score = 85.4 bits (202), Expect = 8e-16
Identities = 109/444 (24%), Positives = 175/444 (39%), Gaps = 33/444 (7%)
Query: 9 FFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEK--GAAVGIVPGSKNLTLLRALDR 65
+ + E+ G+ +G ++ + G E+L R+ K G + + + L + +DR
Sbjct: 33 YSVPEEAKHGTFVGRIAQDLGLELEELVPRLFRVASKRHGDLLEVNLQNGILFVNSRIDR 92
Query: 66 EEKIGPS---NVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXX 122
EE G S +++V V DR P V V V V D+NDN P + +R E+
Sbjct: 93 EELCGRSAECSIHVEVIVDR-----PLQVFHVEVEVKDINDNPPIFPMTVKTIRFPESRL 147
Query: 123 XXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFE--NELEPII--VVKKPLDFETV 178
SD D G ++ L Y L +L + +EL + V+ K LD E
Sbjct: 148 LDSRFPLEGASDADI-GVNALLSYK-LSSSEFFFLDIQANDELSESLSLVLGKSLDREET 205
Query: 179 NNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSP 238
+ L D G P L + + VLD +D P F Y L ++ GT +
Sbjct: 206 AEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQSVYKVKLLENTANGTLVV--- 262
Query: 239 GPISAADQDLGINAPLQYSSTGDHKQLI----VVNKDTGQVAATKQLIAELDPSVTIVLK 294
++A+D D G N+ + YS D I ++ +G++ +L E S I +
Sbjct: 263 -KLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTKGKLDYEEAKSYEIQVT 321
Query: 295 ATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVP 354
AT P + + + S +SE AS G+V+ +T
Sbjct: 322 ATDKGTPSMSGHCKISLKLVDINDNTP-----EVSITSLSLPISENASLGTVIALITVSD 376
Query: 355 QNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSISND-- 412
+++ F N ++L +LD E+ S Y V D S
Sbjct: 377 RDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPSLW 436
Query: 413 -TASINISVEDVNEWEPRFRHPQY 435
T S++I V DVN+ P F P+Y
Sbjct: 437 ATTSVSIEVADVNDNAPAFAQPEY 460
Score = 83.0 bits (196), Expect = 4e-15
Identities = 86/393 (21%), Positives = 167/393 (42%), Gaps = 26/393 (6%)
Query: 54 SKNLTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPY 113
S +L L ++LDREE + + V + T + + ++V DVNDN P + + Y
Sbjct: 191 SLSLVLGKSLDREETAEVNLLLVATDGGKPELTG---TVQILIKVLDVNDNEPTFAQSVY 247
Query: 114 AVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPI---IVVK 170
V++ E SD D+ GP+S + Y+ L S + + ++PI I K
Sbjct: 248 KVKLLENTANGTLVVKLNASDADE-GPNSEIVYS-LGSDVSSTIQTKFTIDPISGEIRTK 305
Query: 171 KPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEE 230
LD+E ++ I++ D+G+P + + + ++D +D P+ + + + ++A
Sbjct: 306 GKLDYEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASL 365
Query: 231 GTFLTTSPGPISAADQDLGINAPLQYSSTGDHK-QLIVVNKDTGQVAATKQLIAELDPSV 289
GT + I+ +D+D G N + S T +L+ K+ + L E +
Sbjct: 366 GTVIAL----ITVSDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAY 421
Query: 290 TIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLT 349
+V+ A +P +A ++ F Q +Y+ V E PG + T
Sbjct: 422 ELVVTARDGGSPSLWATTSVSIEVADVNDNAPA-----FAQPEYTVFVKENNPPGCHIFT 476
Query: 350 LTT----VPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVM 404
++ +N S ++ V +R+ +++ +G+V + LD+E +QV
Sbjct: 477 VSAWDADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVS 536
Query: 405 VTDS---ISNDTASINISVEDVNEWEPRFRHPQ 434
D+ ++ + V D N+ P P+
Sbjct: 537 ARDAGVPPLGSNVTLQVFVLDENDNAPALLAPR 569
Score = 70.5 bits (165), Expect = 2e-11
Identities = 88/318 (27%), Positives = 125/318 (39%), Gaps = 30/318 (9%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKN---LTLLRALDREE 67
ISE+ +G++I ++V+ S G +T L +V KN L L ALDRE
Sbjct: 359 ISENASLGTVIALITVSDRDSGTNGHVTCSLTPH-VPFKLVSTFKNYYSLVLDSALDRES 417
Query: 68 KIGPSNVYVNVRCDRRRTTDPSF--VIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXX 125
+ + V R PS VS+ V DVNDNAP + Y V V E
Sbjct: 418 -VSAYELVVTARDGG----SPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGC 472
Query: 126 XXXXXXXSDRDQPG----PHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNF 181
D D +S + V S Y+ E + ++ PLD E V
Sbjct: 473 HIFTVSAWDADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQ-PLDHEEVELL 531
Query: 182 TIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEH-------YTALLPDDAEEGTFL 234
++ +D G PPL S+ TLQV VLD +D P + L+P G +
Sbjct: 532 QFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVV 591
Query: 235 TTSPGPISAADQDLGINAPLQYS---STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTI 291
+ A D D G NA L Y TG + V TG+++ T+ L P +
Sbjct: 592 ----AKVRAVDADSGYNAWLSYELQLGTGSARIPFRVGLYTGEISTTRALDEADSPRHRL 647
Query: 292 VLKATQVDNPDRYALATL 309
++ P A AT+
Sbjct: 648 LVLVKDHGEPALTATATV 665
Score = 68.9 bits (161), Expect = 7e-11
Identities = 55/209 (26%), Positives = 93/209 (44%), Gaps = 11/209 (5%)
Query: 50 IVPGSKNLTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWE 109
I P S + LD EE + + V + T S +S+++ D+NDN P+
Sbjct: 295 IDPISGEIRTKGKLDYEEA---KSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVS 351
Query: 110 GAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPG-PHSEYLGFENELEPIIV 168
++ +SE SDRD G + + ++ P P F+N +V
Sbjct: 352 ITSLSLPISENASLGTVIALITVSDRDS-GTNGHVTCSLTPHVPFKLVSTFKNYYS--LV 408
Query: 169 VKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDA 228
+ LD E+V+ + + + +D GSP L++ T++ + V D +D P F YT + ++
Sbjct: 409 LDSALDRESVSAYELVVTARDGGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENN 468
Query: 229 EEGTFLTTSPGPISAADQDLGINAPLQYS 257
G + T +SA D D NA + YS
Sbjct: 469 PPGCHIFT----VSAWDADAQENALVSYS 493
>AF152307-1|AAD43701.1| 949|Homo sapiens protocadherin alpha 11
protein.
Length = 949
Score = 85.4 bits (202), Expect = 8e-16
Identities = 102/445 (22%), Positives = 181/445 (40%), Gaps = 36/445 (8%)
Query: 9 FFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEK--GAAVGIVPGSKNLTLLRALDR 65
+ +SE+ G+ +G ++ + G +L R+ K G + + + L + +DR
Sbjct: 33 YSVSEEAKHGTFVGRIAQDLGLELAELVQRLFRVASKTHGDLLEVNLQNGILFVNSRIDR 92
Query: 66 EEKIGPS---NVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXX 122
EE G S ++++ V DR P V V+V V D+NDN P + + ++E+
Sbjct: 93 EELCGQSAECSIHLEVIVDR-----PLQVFHVNVEVKDINDNPPVFSLREQKLLIAESKQ 147
Query: 123 XXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFEN-----ELEPI-IVVKKPLDFE 176
SD D ++ L Y + +EY ++ +++ + +++KK LD E
Sbjct: 148 SDSRFPLEGASDADIE-ENALLTYRL---SKNEYFSLDSPTNGKQIKRLSLILKKSLDRE 203
Query: 177 TVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTT 236
+ L D G P L L V VLD +D +P+F Y L ++A + T +
Sbjct: 204 KTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDPEFDKSEYKVSLMENAAKETLVL- 262
Query: 237 SPGPISAADQDLGINAPLQYSSTG---DHKQLIVVNKDTGQVAATKQLIAELDPSVTIVL 293
++A D+D G+N + YS + + L ++++ G+V L E + I +
Sbjct: 263 ---KLNATDRDEGVNGEVTYSLMSIKPNGRHLFTLDQNNGEVRVNGTLDYEENKFYKIEV 319
Query: 294 KATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTV 353
+AT P T+ + S V E A P +V+ ++
Sbjct: 320 QATDKGTPPMAGHCTVWVEILDTNDNSP-----EVAVTSLSLPVREDAQPSTVIALISVS 374
Query: 354 PQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSISND- 412
+++ F N ++L +LD E Y V D S
Sbjct: 375 DRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAYELVVTARDGGSPSL 434
Query: 413 --TASINISVEDVNEWEPRFRHPQY 435
TA +++ V DVN+ P F P+Y
Sbjct: 435 WATARVSVEVADVNDNAPAFAQPEY 459
Score = 85.4 bits (202), Expect = 8e-16
Identities = 81/360 (22%), Positives = 160/360 (44%), Gaps = 20/360 (5%)
Query: 56 NLTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAV 115
+L L ++LDRE K N+ + + + + + + V+V DVNDN P+++ + Y V
Sbjct: 193 SLILKKSLDRE-KTPELNLLLTATDGGK--PELTGTVRLLVQVLDVNDNDPEFDKSEYKV 249
Query: 116 RVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLP-GPHSEYLGFENELEPIIVVKKPLD 174
+ E +DRD+ G + + Y+++ P+ +L ++ + V LD
Sbjct: 250 SLMENAAKETLVLKLNATDRDE-GVNGEVTYSLMSIKPNGRHLFTLDQNNGEVRVNGTLD 308
Query: 175 FETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFL 234
+E + I+++ D+G+PP+ T+ V +LD +D +P+ + + +DA+ T +
Sbjct: 309 YEENKFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPVREDAQPSTVI 368
Query: 235 TTSPGPISAADQDLGINAPLQYSSTGDHK-QLIVVNKDTGQVAATKQLIAELDPSVTIVL 293
IS +D+D G+N + S T +L+ K+ + L E + +V+
Sbjct: 369 AL----ISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAYELVV 424
Query: 294 KATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTT- 352
A +P +A A + F Q +Y+ V E PG + T++
Sbjct: 425 TARDGGSPSLWATARVSVEVADVNDNAPA-----FAQPEYTVFVKENNPPGCHIFTVSAR 479
Query: 353 ---VPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTDS 408
+N S ++ + DR+ +++ +G+V + LD+E +QV D+
Sbjct: 480 DADAQENALVSYSLVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 539
Score = 64.5 bits (150), Expect = 2e-09
Identities = 87/320 (27%), Positives = 126/320 (39%), Gaps = 34/320 (10%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKN---LTLLRALDREE 67
+ ED ++I +SV+ S G +T L +V KN L L ALDRE
Sbjct: 358 VREDAQPSTVIALISVSDRDSGVNGQVTCSLTPH-VPFKLVSTFKNYYSLVLDSALDRE- 415
Query: 68 KIGPSNVYV-NVRCDRRRTTDPSF--VIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXX 124
NV+ + R PS VSV V DVNDNAP + Y V V E
Sbjct: 416 -----NVWAYELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPG 470
Query: 125 XXXXXXXXSDRDQPGPHSALHYAVLP---GPH--SEYLGFENELEPIIVVKKPLDFETVN 179
D D ++ + Y+++ G S Y+ E + ++ PLD E +
Sbjct: 471 CHIFTVSARDADAQ-ENALVSYSLVERRLGDRALSSYVSVHAESGKVYALQ-PLDHEELE 528
Query: 180 NFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEH-------YTALLPDDAEEGT 232
++ +D G PPL S+ TLQV VLD +D P L+P G
Sbjct: 529 LLQFQVSARDAGVPPLSSNVTLQVFVLDENDNAPALLATQAGSAGGAVNKLVPRSVGAGH 588
Query: 233 FLTTSPGPISAADQDLGINAPLQYS---STGDHKQLIVVNKDTGQVAATKQLIAELDPSV 289
+ + A D D G NA L Y + G + V TG+++ T+ L P
Sbjct: 589 VV----AKVRAVDADSGYNAWLSYELQPAAGGSRIPFRVGLYTGEISTTRALDEADSPRH 644
Query: 290 TIVLKATQVDNPDRYALATL 309
+++ P A AT+
Sbjct: 645 RLLVLVKDHGEPALTATATV 664
>AC005609-12|AAC34324.1| 824|Homo sapiens KIAA0345-like 12 protein.
Length = 824
Score = 85.4 bits (202), Expect = 8e-16
Identities = 109/444 (24%), Positives = 175/444 (39%), Gaps = 33/444 (7%)
Query: 9 FFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEK--GAAVGIVPGSKNLTLLRALDR 65
+ + E+ G+ +G ++ + G E+L R+ K G + + + L + +DR
Sbjct: 33 YSVPEEAKHGTFVGRIAQDLGLELEELVPRLFRVASKRHGDLLEVNLQNGILFVNSRIDR 92
Query: 66 EEKIGPS---NVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXX 122
EE G S +++V V DR P V V V V D+NDN P + +R E+
Sbjct: 93 EELCGRSAECSIHVEVIVDR-----PLQVFHVEVEVKDINDNPPIFPMTVKTIRFPESRL 147
Query: 123 XXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFE--NELEPII--VVKKPLDFETV 178
SD D G ++ L Y L +L + +EL + V+ K LD E
Sbjct: 148 LDSRFPLEGASDADI-GVNALLSYK-LSSSEFFFLDIQANDELSESLSLVLGKSLDREET 205
Query: 179 NNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSP 238
+ L D G P L + + VLD +D P F Y L ++ GT +
Sbjct: 206 AEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQSVYKVKLLENTANGTLVV--- 262
Query: 239 GPISAADQDLGINAPLQYSSTGDHKQLI----VVNKDTGQVAATKQLIAELDPSVTIVLK 294
++A+D D G N+ + YS D I ++ +G++ +L E S I +
Sbjct: 263 -KLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTKGKLDYEEAKSYEIQVT 321
Query: 295 ATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVP 354
AT P + + + S +SE AS G+V+ +T
Sbjct: 322 ATDKGTPSMSGHCKISLKLVDINDNTP-----EVSITSLSLPISENASLGTVIALITVSD 376
Query: 355 QNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSISND-- 412
+++ F N ++L +LD E+ S Y V D S
Sbjct: 377 RDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPSLW 436
Query: 413 -TASINISVEDVNEWEPRFRHPQY 435
T S++I V DVN+ P F P+Y
Sbjct: 437 ATTSVSIEVADVNDNAPAFAQPEY 460
Score = 83.0 bits (196), Expect = 4e-15
Identities = 86/393 (21%), Positives = 167/393 (42%), Gaps = 26/393 (6%)
Query: 54 SKNLTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPY 113
S +L L ++LDREE + + V + T + + ++V DVNDN P + + Y
Sbjct: 191 SLSLVLGKSLDREETAEVNLLLVATDGGKPELTG---TVQILIKVLDVNDNEPTFAQSVY 247
Query: 114 AVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPI---IVVK 170
V++ E SD D+ GP+S + Y+ L S + + ++PI I K
Sbjct: 248 KVKLLENTANGTLVVKLNASDADE-GPNSEIVYS-LGSDVSSTIQTKFTIDPISGEIRTK 305
Query: 171 KPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEE 230
LD+E ++ I++ D+G+P + + + ++D +D P+ + + + ++A
Sbjct: 306 GKLDYEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASL 365
Query: 231 GTFLTTSPGPISAADQDLGINAPLQYSSTGDHK-QLIVVNKDTGQVAATKQLIAELDPSV 289
GT + I+ +D+D G N + S T +L+ K+ + L E +
Sbjct: 366 GTVIAL----ITVSDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAY 421
Query: 290 TIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLT 349
+V+ A +P +A ++ F Q +Y+ V E PG + T
Sbjct: 422 ELVVTARDGGSPSLWATTSVSIEVADVNDNAPA-----FAQPEYTVFVKENNPPGCHIFT 476
Query: 350 LTT----VPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVM 404
++ +N S ++ V +R+ +++ +G+V + LD+E +QV
Sbjct: 477 VSAWDADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVS 536
Query: 405 VTDS---ISNDTASINISVEDVNEWEPRFRHPQ 434
D+ ++ + V D N+ P P+
Sbjct: 537 ARDAGVPPLGSNVTLQVFVLDENDNAPALLAPR 569
Score = 70.5 bits (165), Expect = 2e-11
Identities = 88/318 (27%), Positives = 125/318 (39%), Gaps = 30/318 (9%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKN---LTLLRALDREE 67
ISE+ +G++I ++V+ S G +T L +V KN L L ALDRE
Sbjct: 359 ISENASLGTVIALITVSDRDSGTNGHVTCSLTPH-VPFKLVSTFKNYYSLVLDSALDRES 417
Query: 68 KIGPSNVYVNVRCDRRRTTDPSF--VIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXX 125
+ + V R PS VS+ V DVNDNAP + Y V V E
Sbjct: 418 -VSAYELVVTARDGG----SPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGC 472
Query: 126 XXXXXXXSDRDQPG----PHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNF 181
D D +S + V S Y+ E + ++ PLD E V
Sbjct: 473 HIFTVSAWDADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQ-PLDHEEVELL 531
Query: 182 TIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEH-------YTALLPDDAEEGTFL 234
++ +D G PPL S+ TLQV VLD +D P + L+P G +
Sbjct: 532 QFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVV 591
Query: 235 TTSPGPISAADQDLGINAPLQYS---STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTI 291
+ A D D G NA L Y TG + V TG+++ T+ L P +
Sbjct: 592 ----AKVRAVDADSGYNAWLSYELQLGTGSARIPFRVGLYTGEISTTRALDEADSPRHRL 647
Query: 292 VLKATQVDNPDRYALATL 309
++ P A AT+
Sbjct: 648 LVLVKDHGEPALTATATV 665
Score = 68.9 bits (161), Expect = 7e-11
Identities = 55/209 (26%), Positives = 93/209 (44%), Gaps = 11/209 (5%)
Query: 50 IVPGSKNLTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWE 109
I P S + LD EE + + V + T S +S+++ D+NDN P+
Sbjct: 295 IDPISGEIRTKGKLDYEEA---KSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVS 351
Query: 110 GAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPG-PHSEYLGFENELEPIIV 168
++ +SE SDRD G + + ++ P P F+N +V
Sbjct: 352 ITSLSLPISENASLGTVIALITVSDRDS-GTNGHVTCSLTPHVPFKLVSTFKNYYS--LV 408
Query: 169 VKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDA 228
+ LD E+V+ + + + +D GSP L++ T++ + V D +D P F YT + ++
Sbjct: 409 LDSALDRESVSAYELVVTARDGGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENN 468
Query: 229 EEGTFLTTSPGPISAADQDLGINAPLQYS 257
G + T +SA D D NA + YS
Sbjct: 469 PPGCHIFT----VSAWDADAQENALVSYS 493
>AC005609-3|AAC34316.1| 810|Homo sapiens KIAA0345-like 3 protein.
Length = 810
Score = 85.4 bits (202), Expect = 8e-16
Identities = 102/445 (22%), Positives = 181/445 (40%), Gaps = 36/445 (8%)
Query: 9 FFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEK--GAAVGIVPGSKNLTLLRALDR 65
+ +SE+ G+ +G ++ + G +L R+ K G + + + L + +DR
Sbjct: 33 YSVSEEAKHGTFVGRIAQDLGLELAELVQRLFRVASKTHGDLLEVNLQNGILFVNSRIDR 92
Query: 66 EEKIGPS---NVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXX 122
EE G S ++++ V DR P V V+V V D+NDN P + + ++E+
Sbjct: 93 EELCGQSAECSIHLEVIVDR-----PLQVFHVNVEVKDINDNPPVFSLREQKLLIAESKQ 147
Query: 123 XXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFEN-----ELEPI-IVVKKPLDFE 176
SD D ++ L Y + +EY ++ +++ + +++KK LD E
Sbjct: 148 SDSRFPLEGASDADIE-ENALLTYRL---SKNEYFSLDSPTNGKQIKRLSLILKKSLDRE 203
Query: 177 TVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTT 236
+ L D G P L L V VLD +D +P+F Y L ++A + T +
Sbjct: 204 KTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDPEFDKSEYKVSLMENAAKETLVL- 262
Query: 237 SPGPISAADQDLGINAPLQYSSTG---DHKQLIVVNKDTGQVAATKQLIAELDPSVTIVL 293
++A D+D G+N + YS + + L ++++ G+V L E + I +
Sbjct: 263 ---KLNATDRDEGVNGEVTYSLMSIKPNGRHLFTLDQNNGEVRVNGTLDYEENKFYKIEV 319
Query: 294 KATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTV 353
+AT P T+ + S V E A P +V+ ++
Sbjct: 320 QATDKGTPPMAGHCTVWVEILDTNDNSP-----EVAVTSLSLPVREDAQPSTVIALISVS 374
Query: 354 PQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSISND- 412
+++ F N ++L +LD E Y V D S
Sbjct: 375 DRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAYELVVTARDGGSPSL 434
Query: 413 --TASINISVEDVNEWEPRFRHPQY 435
TA +++ V DVN+ P F P+Y
Sbjct: 435 WATARVSVEVADVNDNAPAFAQPEY 459
Score = 85.4 bits (202), Expect = 8e-16
Identities = 81/360 (22%), Positives = 160/360 (44%), Gaps = 20/360 (5%)
Query: 56 NLTLLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAV 115
+L L ++LDRE K N+ + + + + + + V+V DVNDN P+++ + Y V
Sbjct: 193 SLILKKSLDRE-KTPELNLLLTATDGGK--PELTGTVRLLVQVLDVNDNDPEFDKSEYKV 249
Query: 116 RVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLP-GPHSEYLGFENELEPIIVVKKPLD 174
+ E +DRD+ G + + Y+++ P+ +L ++ + V LD
Sbjct: 250 SLMENAAKETLVLKLNATDRDE-GVNGEVTYSLMSIKPNGRHLFTLDQNNGEVRVNGTLD 308
Query: 175 FETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFL 234
+E + I+++ D+G+PP+ T+ V +LD +D +P+ + + +DA+ T +
Sbjct: 309 YEENKFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPVREDAQPSTVI 368
Query: 235 TTSPGPISAADQDLGINAPLQYSSTGDHK-QLIVVNKDTGQVAATKQLIAELDPSVTIVL 293
IS +D+D G+N + S T +L+ K+ + L E + +V+
Sbjct: 369 AL----ISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAYELVV 424
Query: 294 KATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTT- 352
A +P +A A + F Q +Y+ V E PG + T++
Sbjct: 425 TARDGGSPSLWATARVSVEVADVNDNAPA-----FAQPEYTVFVKENNPPGCHIFTVSAR 479
Query: 353 ---VPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTDS 408
+N S ++ + DR+ +++ +G+V + LD+E +QV D+
Sbjct: 480 DADAQENALVSYSLVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 539
Score = 64.5 bits (150), Expect = 2e-09
Identities = 87/320 (27%), Positives = 126/320 (39%), Gaps = 34/320 (10%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKN---LTLLRALDREE 67
+ ED ++I +SV+ S G +T L +V KN L L ALDRE
Sbjct: 358 VREDAQPSTVIALISVSDRDSGVNGQVTCSLTPH-VPFKLVSTFKNYYSLVLDSALDRE- 415
Query: 68 KIGPSNVYV-NVRCDRRRTTDPSF--VIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXX 124
NV+ + R PS VSV V DVNDNAP + Y V V E
Sbjct: 416 -----NVWAYELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPG 470
Query: 125 XXXXXXXXSDRDQPGPHSALHYAVLP---GPH--SEYLGFENELEPIIVVKKPLDFETVN 179
D D ++ + Y+++ G S Y+ E + ++ PLD E +
Sbjct: 471 CHIFTVSARDADAQ-ENALVSYSLVERRLGDRALSSYVSVHAESGKVYALQ-PLDHEELE 528
Query: 180 NFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEH-------YTALLPDDAEEGT 232
++ +D G PPL S+ TLQV VLD +D P L+P G
Sbjct: 529 LLQFQVSARDAGVPPLSSNVTLQVFVLDENDNAPALLATQAGSAGGAVNKLVPRSVGAGH 588
Query: 233 FLTTSPGPISAADQDLGINAPLQYS---STGDHKQLIVVNKDTGQVAATKQLIAELDPSV 289
+ + A D D G NA L Y + G + V TG+++ T+ L P
Sbjct: 589 VV----AKVRAVDADSGYNAWLSYELQPAAGGSRIPFRVGLYTGEISTTRALDEADSPRH 644
Query: 290 TIVLKATQVDNPDRYALATL 309
+++ P A AT+
Sbjct: 645 RLLVLVKDHGEPALTATATV 664
>BC130331-1|AAI30332.1| 793|Homo sapiens protocadherin beta 7
protein.
Length = 793
Score = 85.0 bits (201), Expect = 1e-15
Identities = 93/441 (21%), Positives = 185/441 (41%), Gaps = 31/441 (7%)
Query: 9 FFISEDTPIGSIIGTLSVNGDPSEDLGDITLR----LQEKGAAVGIVPG-SKNLTLLRAL 63
+F++E+T G+ + L+ D +G++ R + ++ + ++ + +L L L
Sbjct: 33 YFVAEETERGTFLTNLAK--DLGLGVGELRARGTRIVSDQNMQILLLSSLTGDLLLNEKL 90
Query: 64 DREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXX 123
DREE GP V + P + + V D+ND+AP + ++++ E+
Sbjct: 91 DREELCGPREPCVLPF--QLLLEKPFQIFRAELWVRDINDHAPVFLDREISLKILESTTP 148
Query: 124 XXXXXXXXXSDRDQPGPHSALHYAVLPGPH---SEYLGFENELEPIIVVKKPLDFETVNN 180
D D G +S +Y + P + + + E + P +V+ + LD E +
Sbjct: 149 GAAFLLESAQDSDV-GTNSLSNYTISPNAYFHINVHDSGEGNIYPELVLNQVLDREEIPE 207
Query: 181 FTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGP 240
F++ L D GSPP +++ VLD +D P F Y +P+++ G+ + +
Sbjct: 208 FSLTLTALDGGSPPRSGTALVRILVLDVNDNAPDFVRSLYKVQVPENSPVGSMVVS---- 263
Query: 241 ISAADQDLGINAPLQYSSTGDHKQLI---VVNKDTGQVAATKQLIAELDPSVTIVLKATQ 297
+SA D D G N + Y+ + ++++ +N +G + QL E + T+ ++A
Sbjct: 264 VSARDLDTGSNGEIAYAFSYATERILKTFQINPTSGSLHLKAQLDYEAIQTYTLTIQAK- 322
Query: 298 VDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNT 357
D T+ + ++ ++E SP +V+ +++
Sbjct: 323 -DGGGLSGKCTVVVDVTDINDNRP-----ELLLSSLTSPIAEN-SPETVVAVFRIRDRDS 375
Query: 358 EFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSIS---NDTA 414
+ D F+ K ++ N ++ + LD E + Y + VTD +
Sbjct: 376 GNNGKTVCSIQDDVPFILKPSVENFYTLVTEKPLDRERNTEYNITITVTDLGTPRLKTEH 435
Query: 415 SINISVEDVNEWEPRFRHPQY 435
+I + V DVN+ P F Y
Sbjct: 436 NITVLVSDVNDNAPAFTQTSY 456
Score = 74.5 bits (175), Expect = 1e-12
Identities = 105/441 (23%), Positives = 159/441 (36%), Gaps = 27/441 (6%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
V + V DVNDNAP + + Y V+V E D D G + + YA
Sbjct: 228 VRILVLDVNDNAPDFVRSLYKVQVPENSPVGSMVVSVSARDLDT-GSNGEIAYAFSYATE 286
Query: 154 SEYLGFE-NELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQN 212
F+ N + +K LD+E + +T+ ++ +D G L T+ V V D +D
Sbjct: 287 RILKTFQINPTSGSLHLKAQLDYEAIQTYTLTIQAKDGGG--LSGKCTVVVDVTDINDNR 344
Query: 213 PKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDT 272
P+ T+ + +++ E T D+D G N S D ++ + +
Sbjct: 345 PELLLSSLTSPIAENSPE-----TVVAVFRIRDRDSGNNGKTVCSIQDDVPFILKPSVEN 399
Query: 273 GQVAAT-KQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQK 331
T K L E + I + T + P L T FTQ
Sbjct: 400 FYTLVTEKPLDRERNTEYNITITVTDLGTP---RLKTEHNITVLVSDVNDNAPA--FTQT 454
Query: 332 QYSTTVSEGASP----GSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVI 386
Y+ V E SP GSV T N + S L +IN + G +
Sbjct: 455 SYTLFVRENNSPALPIGSVSATDRDSGTNAQVIYSLLPSQDPHLPLASLVSINADNGHLF 514
Query: 387 LRRSLDYETTSNYFYQVMVTDSIS---NDTASINISVEDVNEWEPRFRHPQYEFEXXXXX 443
RSLDYE + ++V TD S + A + + V D N+ P +P
Sbjct: 515 ALRSLDYEALQAFEFRVGATDRGSPALSSEALVRVLVLDANDNSPFVLYPLQNSSAPCTE 574
Query: 444 XXXXXXXXXXXXXXXVAHDGDAGTLA-LS---LAGQHARMFYINASGDLFLREEAIGNLN 499
VA DGD+G A LS L +F + A + +
Sbjct: 575 PLPRAAEPGYLVTKVVAVDGDSGQNAWLSYQLLKATEPGLFGVWAHNGEVRTARLLSERD 634
Query: 500 SSSLHLVATAIDSGIPPRQTS 520
++ LV D+G PPR +
Sbjct: 635 AAKQRLVVLVKDNGEPPRSAT 655
Score = 74.5 bits (175), Expect = 1e-12
Identities = 70/228 (30%), Positives = 101/228 (44%), Gaps = 18/228 (7%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPG-- 151
++V V DVNDNAP + Y + V E +DRD G ++ + Y++LP
Sbjct: 437 ITVLVSDVNDNAPAFTQTSYTLFVRENNSPALPIGSVSATDRDS-GTNAQVIYSLLPSQD 495
Query: 152 PHSEYLGFE--NELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDAD 209
PH N + + LD+E + F ++ D+GSP L S+ ++V VLDA+
Sbjct: 496 PHLPLASLVSINADNGHLFALRSLDYEALQAFEFRVGATDRGSPALSSEALVRVLVLDAN 555
Query: 210 DQNPKFTY------EHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYS-STGDH 262
D +P Y T LP AE G +T + A D D G NA L Y
Sbjct: 556 DNSPFVLYPLQNSSAPCTEPLPRAAEPGYLVT----KVVAVDGDSGQNAWLSYQLLKATE 611
Query: 263 KQLIVVNKDTGQVAATKQLIAELDPS-VTIVLKATQVDNPDRYALATL 309
L V G+V T +L++E D + +V+ P R A ATL
Sbjct: 612 PGLFGVWAHNGEV-RTARLLSERDAAKQRLVVLVKDNGEPPRSATATL 658
>BC101038-1|AAI01039.1| 871|Homo sapiens protocadherin gamma
subfamily C, 4 protein.
Length = 871
Score = 85.0 bits (201), Expect = 1e-15
Identities = 91/352 (25%), Positives = 138/352 (39%), Gaps = 25/352 (7%)
Query: 96 VRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSE 155
V V DVNDNAP ++ + Y + V E+ SD D GP + + G +
Sbjct: 230 VSVLDVNDNAPAFQQSSYRISVLESAPAGMVLIQLNASDPDL-GPSGNVTF-YFSGHTPD 287
Query: 156 YLGFENELEPI---IVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQN 212
+ L P + + PLDFE+ N + +R +D GSP + +L+V +LD +D
Sbjct: 288 RVRNLFSLHPTTGKLTLLGPLDFESENYYEFDVRARDGGSPAMEQHCSLRVDLLDVNDNA 347
Query: 213 PKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDT 272
P T LP+ AE GT + IS D D G N + DH + +
Sbjct: 348 PYITVTSELGTLPESAEPGTVVAL----ISVQDPDSGSNGDVSL-RIPDHLPFALKSAFR 402
Query: 273 GQ--VAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQ 330
Q + L E S I++ A+ NP T+ F Q
Sbjct: 403 NQFSLVTAGPLDREAKSSYDIMVTASDAGNPPLSTHRTIFLNISDVNDNPP-----SFFQ 457
Query: 331 KQYSTTVSEGASPGSVLLTLTTVPQ----NTEFRESPLQFYVSDRSFLDKFAIN-NAGEV 385
+ + V E PG +L +L N S L+ D S ++N G V
Sbjct: 458 RSHEVFVPENNRPGDLLCSLAASDPDSGLNALISYSLLEPRNRDVSASSFISLNPQTGAV 517
Query: 386 ILRRSLDYETTSNYFYQVMVTDSIS---NDTASINISVEDVNEWEPRFRHPQ 434
RS DYE T ++V D + + T ++ + V D+N+ P P+
Sbjct: 518 HATRSFDYEQTQTLQFEVQARDRGNPPLSSTVTVRLFVLDLNDNAPAVLRPR 569
Score = 72.1 bits (169), Expect = 8e-12
Identities = 82/363 (22%), Positives = 142/363 (39%), Gaps = 22/363 (6%)
Query: 85 TTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSAL 144
T P + V + DVND+AP++ + + E D D G +S
Sbjct: 110 TEGPLEMYRAEVEIVDVNDHAPRFPRQQLDLEIGEAAPPGQRFPLEKAQDADV-GSNSIS 168
Query: 145 HYAVLPGPHSEY---LGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTL 201
Y + H + L P ++++KPLD E +++ + L D G+PP L
Sbjct: 169 SYRLSSNEHFALDVKKRSDGSLVPELLLEKPLDREKQSDYRLVLTAVDGGNPPRSGTAEL 228
Query: 202 QVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGD 261
+V+VLD +D P F Y + + A G L ++A+D DLG + + + +G
Sbjct: 229 RVSVLDVNDNAPAFQQSSYRISVLESAPAGMVLI----QLNASDPDLGPSGNVTFYFSGH 284
Query: 262 H----KQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXX 317
+ L ++ TG++ L E + ++A +P +L
Sbjct: 285 TPDRVRNLFSLHPTTGKLTLLGPLDFESENYYEFDVRARDGGSPAMEQHCSLRVDLLDVN 344
Query: 318 XXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDR-SFLDK 376
T T+ E A PG+V + L +V + + D F K
Sbjct: 345 DNAP-----YITVTSELGTLPESAEPGTV-VALISVQDPDSGSNGDVSLRIPDHLPFALK 398
Query: 377 FAINNAGEVILRRSLDYETTSNYFYQVMVTDSIS---NDTASINISVEDVNEWEPRFRHP 433
A N ++ LD E S+Y V +D+ + + +I +++ DVN+ P F
Sbjct: 399 SAFRNQFSLVTAGPLDREAKSSYDIMVTASDAGNPPLSTHRTIFLNISDVNDNPPSFFQR 458
Query: 434 QYE 436
+E
Sbjct: 459 SHE 461
Score = 64.5 bits (150), Expect = 2e-09
Identities = 67/293 (22%), Positives = 117/293 (39%), Gaps = 15/293 (5%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQE--KGAAVGIVPGSKNLTLLRALDREEK 68
+ E G+++ +SV S GD++LR+ + A +L LDRE K
Sbjct: 359 LPESAEPGTVVALISVQDPDSGSNGDVSLRIPDHLPFALKSAFRNQFSLVTAGPLDREAK 418
Query: 69 IGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXX 128
S+ + V S + + + DVNDN P + + V V E
Sbjct: 419 ---SSYDIMVTASDAGNPPLSTHRTIFLNISDVNDNPPSFFQRSHEVFVPENNRPGDLLC 475
Query: 129 XXXXSDRDQPGPHSALHYAVLPGPHSEYLGFEN--ELEP---IIVVKKPLDFETVNNFTI 183
SD D G ++ + Y++L P + + + L P + + D+E
Sbjct: 476 SLAASDPDS-GLNALISYSLLE-PRNRDVSASSFISLNPQTGAVHATRSFDYEQTQTLQF 533
Query: 184 KLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYT--ALLPDDAEEGTFLTTSPGPI 241
+++ +D+G+PPL S T+++ VLD +D P +L P +
Sbjct: 534 EVQARDRGNPPLSSTVTVRLFVLDLNDNAPAVLRPRARPGSLCPQALPPSVGAGHLITKV 593
Query: 242 SAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVL 293
+A D D G NA + Y L V++ G+V + A+L P +++
Sbjct: 594 TAVDLDSGYNAWVSYQLLEAPDPSLFAVSRYAGEVRTAVPIPADLPPQKLVIV 646
>BC101036-1|AAI01037.1| 870|Homo sapiens PCDHGC4 protein protein.
Length = 870
Score = 85.0 bits (201), Expect = 1e-15
Identities = 91/352 (25%), Positives = 138/352 (39%), Gaps = 25/352 (7%)
Query: 96 VRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSE 155
V V DVNDNAP ++ + Y + V E+ SD D GP + + G +
Sbjct: 229 VSVLDVNDNAPAFQQSSYRISVLESAPAGMVLIQLNASDPDL-GPSGNVTF-YFSGHTPD 286
Query: 156 YLGFENELEPI---IVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQN 212
+ L P + + PLDFE+ N + +R +D GSP + +L+V +LD +D
Sbjct: 287 RVRNLFSLHPTTGKLTLLGPLDFESENYYEFDVRARDGGSPAMEQHCSLRVDLLDVNDNA 346
Query: 213 PKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDT 272
P T LP+ AE GT + IS D D G N + DH + +
Sbjct: 347 PYITVTSELGTLPESAEPGTVVAL----ISVQDPDSGSNGDVSL-RIPDHLPFALKSAFR 401
Query: 273 GQ--VAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQ 330
Q + L E S I++ A+ NP T+ F Q
Sbjct: 402 NQFSLVTAGPLDREAKSSYDIMVTASDAGNPPLSTHRTIFLNISDVNDNPP-----SFFQ 456
Query: 331 KQYSTTVSEGASPGSVLLTLTTVPQ----NTEFRESPLQFYVSDRSFLDKFAIN-NAGEV 385
+ + V E PG +L +L N S L+ D S ++N G V
Sbjct: 457 RSHEVFVPENNRPGDLLCSLAASDPDSGLNALISYSLLEPRNRDVSASSFISLNPQTGAV 516
Query: 386 ILRRSLDYETTSNYFYQVMVTDSIS---NDTASINISVEDVNEWEPRFRHPQ 434
RS DYE T ++V D + + T ++ + V D+N+ P P+
Sbjct: 517 HATRSFDYEQTQTLQFEVQARDRGNPPLSSTVTVRLFVLDLNDNAPAVLRPR 568
Score = 72.1 bits (169), Expect = 8e-12
Identities = 82/363 (22%), Positives = 142/363 (39%), Gaps = 22/363 (6%)
Query: 85 TTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSAL 144
T P + V + DVND+AP++ + + E D D G +S
Sbjct: 109 TEGPLEMYRAEVEIVDVNDHAPRFPRQQLDLEIGEAAPPGQRFPLEKAQDADV-GSNSIS 167
Query: 145 HYAVLPGPHSEY---LGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTL 201
Y + H + L P ++++KPLD E +++ + L D G+PP L
Sbjct: 168 SYRLSSNEHFALDVKKRSDGSLVPELLLEKPLDREKQSDYRLVLTAVDGGNPPRSGTAEL 227
Query: 202 QVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGD 261
+V+VLD +D P F Y + + A G L ++A+D DLG + + + +G
Sbjct: 228 RVSVLDVNDNAPAFQQSSYRISVLESAPAGMVLI----QLNASDPDLGPSGNVTFYFSGH 283
Query: 262 H----KQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXX 317
+ L ++ TG++ L E + ++A +P +L
Sbjct: 284 TPDRVRNLFSLHPTTGKLTLLGPLDFESENYYEFDVRARDGGSPAMEQHCSLRVDLLDVN 343
Query: 318 XXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDR-SFLDK 376
T T+ E A PG+V + L +V + + D F K
Sbjct: 344 DNAP-----YITVTSELGTLPESAEPGTV-VALISVQDPDSGSNGDVSLRIPDHLPFALK 397
Query: 377 FAINNAGEVILRRSLDYETTSNYFYQVMVTDSIS---NDTASINISVEDVNEWEPRFRHP 433
A N ++ LD E S+Y V +D+ + + +I +++ DVN+ P F
Sbjct: 398 SAFRNQFSLVTAGPLDREAKSSYDIMVTASDAGNPPLSTHRTIFLNISDVNDNPPSFFQR 457
Query: 434 QYE 436
+E
Sbjct: 458 SHE 460
Score = 64.5 bits (150), Expect = 2e-09
Identities = 67/293 (22%), Positives = 117/293 (39%), Gaps = 15/293 (5%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQE--KGAAVGIVPGSKNLTLLRALDREEK 68
+ E G+++ +SV S GD++LR+ + A +L LDRE K
Sbjct: 358 LPESAEPGTVVALISVQDPDSGSNGDVSLRIPDHLPFALKSAFRNQFSLVTAGPLDREAK 417
Query: 69 IGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXX 128
S+ + V S + + + DVNDN P + + V V E
Sbjct: 418 ---SSYDIMVTASDAGNPPLSTHRTIFLNISDVNDNPPSFFQRSHEVFVPENNRPGDLLC 474
Query: 129 XXXXSDRDQPGPHSALHYAVLPGPHSEYLGFEN--ELEP---IIVVKKPLDFETVNNFTI 183
SD D G ++ + Y++L P + + + L P + + D+E
Sbjct: 475 SLAASDPDS-GLNALISYSLLE-PRNRDVSASSFISLNPQTGAVHATRSFDYEQTQTLQF 532
Query: 184 KLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYT--ALLPDDAEEGTFLTTSPGPI 241
+++ +D+G+PPL S T+++ VLD +D P +L P +
Sbjct: 533 EVQARDRGNPPLSSTVTVRLFVLDLNDNAPAVLRPRARPGSLCPQALPPSVGAGHLITKV 592
Query: 242 SAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVL 293
+A D D G NA + Y L V++ G+V + A+L P +++
Sbjct: 593 TAVDLDSGYNAWVSYQLLEAPDPSLFAVSRYAGEVRTAVPIPADLPPQKLVIV 645
>BC101035-1|AAI01036.1| 871|Homo sapiens protocadherin gamma
subfamily C, 4 protein.
Length = 871
Score = 85.0 bits (201), Expect = 1e-15
Identities = 91/352 (25%), Positives = 138/352 (39%), Gaps = 25/352 (7%)
Query: 96 VRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSE 155
V V DVNDNAP ++ + Y + V E+ SD D GP + + G +
Sbjct: 230 VSVLDVNDNAPAFQQSSYRISVLESAPAGMVLIQLNASDPDL-GPSGNVTF-YFSGHTPD 287
Query: 156 YLGFENELEPI---IVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQN 212
+ L P + + PLDFE+ N + +R +D GSP + +L+V +LD +D
Sbjct: 288 RVRNLFSLHPTTGKLTLLGPLDFESENYYEFDVRARDGGSPAMEQHCSLRVDLLDVNDNA 347
Query: 213 PKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDT 272
P T LP+ AE GT + IS D D G N + DH + +
Sbjct: 348 PYITVTSELGTLPESAEPGTVVAL----ISVQDPDSGSNGDVSL-RIPDHLPFALKSAFR 402
Query: 273 GQ--VAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQ 330
Q + L E S I++ A+ NP T+ F Q
Sbjct: 403 NQFSLVTAGPLDREAKSSYDIMVTASDAGNPPLSTHRTIFLNISDVNDNPP-----SFFQ 457
Query: 331 KQYSTTVSEGASPGSVLLTLTTVPQ----NTEFRESPLQFYVSDRSFLDKFAIN-NAGEV 385
+ + V E PG +L +L N S L+ D S ++N G V
Sbjct: 458 RSHEVFVPENNRPGDLLCSLAASDPDSGLNALISYSLLEPRNRDVSASSFISLNPQTGAV 517
Query: 386 ILRRSLDYETTSNYFYQVMVTDSIS---NDTASINISVEDVNEWEPRFRHPQ 434
RS DYE T ++V D + + T ++ + V D+N+ P P+
Sbjct: 518 HATRSFDYEQTQTLQFEVQARDRGNPPLSSTVTVRLFVLDLNDNAPAVLRPR 569
Score = 72.1 bits (169), Expect = 8e-12
Identities = 82/363 (22%), Positives = 142/363 (39%), Gaps = 22/363 (6%)
Query: 85 TTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSAL 144
T P + V + DVND+AP++ + + E D D G +S
Sbjct: 110 TEGPLEMYRAEVEIVDVNDHAPRFPRQQLDLEIGEAAPPGQRFPLEKAQDADV-GSNSIS 168
Query: 145 HYAVLPGPHSEY---LGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTL 201
Y + H + L P ++++KPLD E +++ + L D G+PP L
Sbjct: 169 SYRLSSNEHFALDVKKRSDGSLVPELLLEKPLDREKQSDYRLVLTAVDGGNPPRSGTAEL 228
Query: 202 QVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGD 261
+V+VLD +D P F Y + + A G L ++A+D DLG + + + +G
Sbjct: 229 RVSVLDVNDNAPAFQQSSYRISVLESAPAGMVLI----QLNASDPDLGPSGNVTFYFSGH 284
Query: 262 H----KQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXX 317
+ L ++ TG++ L E + ++A +P +L
Sbjct: 285 TPDRVRNLFSLHPTTGKLTLLGPLDFESENYYEFDVRARDGGSPAMEQHCSLRVDLLDVN 344
Query: 318 XXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDR-SFLDK 376
T T+ E A PG+V + L +V + + D F K
Sbjct: 345 DNAP-----YITVTSELGTLPESAEPGTV-VALISVQDPDSGSNGDVSLRIPDHLPFALK 398
Query: 377 FAINNAGEVILRRSLDYETTSNYFYQVMVTDSIS---NDTASINISVEDVNEWEPRFRHP 433
A N ++ LD E S+Y V +D+ + + +I +++ DVN+ P F
Sbjct: 399 SAFRNQFSLVTAGPLDREAKSSYDIMVTASDAGNPPLSTHRTIFLNISDVNDNPPSFFQR 458
Query: 434 QYE 436
+E
Sbjct: 459 SHE 461
Score = 64.5 bits (150), Expect = 2e-09
Identities = 67/293 (22%), Positives = 117/293 (39%), Gaps = 15/293 (5%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQE--KGAAVGIVPGSKNLTLLRALDREEK 68
+ E G+++ +SV S GD++LR+ + A +L LDRE K
Sbjct: 359 LPESAEPGTVVALISVQDPDSGSNGDVSLRIPDHLPFALKSAFRNQFSLVTAGPLDREAK 418
Query: 69 IGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXX 128
S+ + V S + + + DVNDN P + + V V E
Sbjct: 419 ---SSYDIMVTASDAGNPPLSTHRTIFLNISDVNDNPPSFFQRSHEVFVPENNRPGDLLC 475
Query: 129 XXXXSDRDQPGPHSALHYAVLPGPHSEYLGFEN--ELEP---IIVVKKPLDFETVNNFTI 183
SD D G ++ + Y++L P + + + L P + + D+E
Sbjct: 476 SLAASDPDS-GLNALISYSLLE-PRNRDVSASSFISLNPQTGAVHATRSFDYEQTQTLQF 533
Query: 184 KLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYT--ALLPDDAEEGTFLTTSPGPI 241
+++ +D+G+PPL S T+++ VLD +D P +L P +
Sbjct: 534 EVQARDRGNPPLSSTVTVRLFVLDLNDNAPAVLRPRARPGSLCPQALPPSVGAGHLITKV 593
Query: 242 SAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVL 293
+A D D G NA + Y L V++ G+V + A+L P +++
Sbjct: 594 TAVDLDSGYNAWVSYQLLEAPDPSLFAVSRYAGEVRTAVPIPADLPPQKLVIV 646
>BC013609-1|AAH13609.1| 796|Homo sapiens cadherin 11, type 2,
OB-cadherin (osteoblast) protein.
Length = 796
Score = 85.0 bits (201), Expect = 1e-15
Identities = 108/453 (23%), Positives = 179/453 (39%), Gaps = 32/453 (7%)
Query: 3 GGAVESFFISEDT--PIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSK--NLT 58
G FF+ E+ P ++G L + D + G+I L +GA V K N+
Sbjct: 54 GWVWNQFFVIEEYTGPDPVLVGRLHSDIDSGD--GNIKYILSGEGAGTIFVIDDKSGNIH 111
Query: 59 LLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVS 118
+ LDREE+ + + V D R +P V V+ D+NDN P++ Y V
Sbjct: 112 ATKTLDREERAQYTLMAQAVDRDTNRPLEPPSEFIVKVQ--DINDNPPEFLHETYHANVP 169
Query: 119 ETXXXXXXXXXXXXSDRDQP--GPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFE 176
E SD D P G + L Y++L G Y E + I +D E
Sbjct: 170 ERSNVGTSVIQVTASDADDPTYGNSAKLVYSILEG--QPYFSVEAQTGIIRTALPNMDRE 227
Query: 177 TVNNFTIKLRVQDQGS--PPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFL 234
+ + ++ +D G L T + +T+ D +D PKF Y + + A G
Sbjct: 228 AKEEYHVVIQAKDMGGHMGGLSGTTKVMITLTDVNDNPPKFPQSVYQMSVSEAAVPG--- 284
Query: 235 TTSPGPISAADQDLGINAPLQYSST-GDHKQLIVVNKD----TGQVAATKQLIAELDPSV 289
G + A D D+G N + Y+ GD + + D G + K + E +
Sbjct: 285 -EEVGRVKAKDPDIGENGLVTYNIVDGDGMESFEITTDYETQEGVIKLKKPVDFETKRAY 343
Query: 290 TIVLKATQVD-NPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLL 348
++ ++A V +P + F Y V E A+ G+V+
Sbjct: 344 SLKVEAANVHIDPKFISNGPFKDTVTVKIAVEDADEPPMFLAPSYIHEVQENAAAGTVVG 403
Query: 349 TLTTVPQNTEFRESPLQFYVSDRSFLDK-FAIN-NAGEVILRRSLDYETTSNYFYQVMVT 406
+ ++ + SP+++ + + LD+ F IN G + + LD E T+ V
Sbjct: 404 RVHA--KDPDAANSPIRYSIDRHTDLDRFFTINPEDGFIKTTKPLDREETAWLNITVFAA 461
Query: 407 DSISNDTAS---INISVEDVNEWEPRFRHPQYE 436
+ + + + I V DVN+ P+F P YE
Sbjct: 462 EIHNRHQEAKVPVAIRVLDVNDNAPKFAAP-YE 493
Score = 37.5 bits (83), Expect = 0.21
Identities = 30/126 (23%), Positives = 53/126 (42%), Gaps = 9/126 (7%)
Query: 92 IPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXX----XXXXXSDRDQP--GPH--SA 143
+PV++RV DVNDNAP++ APY + E+ D+D GP +
Sbjct: 472 VPVAIRVLDVNDNAPKF-AAPYEGFICESDQTKPLSNQPIVTISADDKDDTANGPRFIFS 530
Query: 144 LHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQV 203
L ++ P+ + + + + + + + + + D G PP+ S TL +
Sbjct: 531 LPPEIIHNPNFTVRDNRDNTAGVYARRGGFSRQKQDLYLLPIVISDGGIPPMSSTNTLTI 590
Query: 204 TVLDAD 209
V D
Sbjct: 591 KVCGCD 596
>AF217750-1|AAK51617.1| 793|Homo sapiens protocadherin-beta7
protein.
Length = 793
Score = 85.0 bits (201), Expect = 1e-15
Identities = 93/441 (21%), Positives = 185/441 (41%), Gaps = 31/441 (7%)
Query: 9 FFISEDTPIGSIIGTLSVNGDPSEDLGDITLR----LQEKGAAVGIVPG-SKNLTLLRAL 63
+F++E+T G+ + L+ D +G++ R + ++ + ++ + +L L L
Sbjct: 33 YFVAEETERGTFLTNLAK--DLGLGVGELRARGTRIVSDQNMQILLLSSLTGDLLLNEKL 90
Query: 64 DREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXX 123
DREE GP V + P + + V D+ND+AP + ++++ E+
Sbjct: 91 DREELCGPREPCVLPF--QLLLEKPFQIFRAELWVRDINDHAPVFLDREISLKILESTTP 148
Query: 124 XXXXXXXXXSDRDQPGPHSALHYAVLPGPH---SEYLGFENELEPIIVVKKPLDFETVNN 180
D D G +S +Y + P + + + E + P +V+ + LD E +
Sbjct: 149 GAAFLLESAQDSDV-GTNSLSNYTISPNAYFHINVHDSGEGNIYPELVLNQVLDREEIPE 207
Query: 181 FTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGP 240
F++ L D GSPP +++ VLD +D P F Y +P+++ G+ + +
Sbjct: 208 FSLTLTALDGGSPPRSGTALVRILVLDVNDNAPDFVRSLYKVQVPENSPVGSMVVS---- 263
Query: 241 ISAADQDLGINAPLQYSSTGDHKQLI---VVNKDTGQVAATKQLIAELDPSVTIVLKATQ 297
+SA D D G N + Y+ + ++++ +N +G + QL E + T+ ++A
Sbjct: 264 VSARDLDTGSNGEIAYAFSYATERILKTFQINPTSGSLHLKAQLDYEAIQTYTLTIQAK- 322
Query: 298 VDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNT 357
D T+ + ++ ++E SP +V+ +++
Sbjct: 323 -DGGGLSGKCTVVVDVTDINDNRP-----ELLLSSLTSPIAEN-SPETVVAVFRIRDRDS 375
Query: 358 EFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSIS---NDTA 414
+ D F+ K ++ N ++ + LD E + Y + VTD +
Sbjct: 376 GNNGKTVCSIQDDVPFILKPSVENFYTLVTEKPLDRERNTEYNITITVTDLGTPRLKTEH 435
Query: 415 SINISVEDVNEWEPRFRHPQY 435
+I + V DVN+ P F Y
Sbjct: 436 NITVLVSDVNDNAPAFTQTSY 456
Score = 74.5 bits (175), Expect = 1e-12
Identities = 105/441 (23%), Positives = 159/441 (36%), Gaps = 27/441 (6%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
V + V DVNDNAP + + Y V+V E D D G + + YA
Sbjct: 228 VRILVLDVNDNAPDFVRSLYKVQVPENSPVGSMVVSVSARDLDT-GSNGEIAYAFSYATE 286
Query: 154 SEYLGFE-NELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQN 212
F+ N + +K LD+E + +T+ ++ +D G L T+ V V D +D
Sbjct: 287 RILKTFQINPTSGSLHLKAQLDYEAIQTYTLTIQAKDGGG--LSGKCTVVVDVTDINDNR 344
Query: 213 PKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDT 272
P+ T+ + +++ E T D+D G N S D ++ + +
Sbjct: 345 PELLLSSLTSPIAENSPE-----TVVAVFRIRDRDSGNNGKTVCSIQDDVPFILKPSVEN 399
Query: 273 GQVAAT-KQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQK 331
T K L E + I + T + P L T FTQ
Sbjct: 400 FYTLVTEKPLDRERNTEYNITITVTDLGTP---RLKTEHNITVLVSDVNDNAPA--FTQT 454
Query: 332 QYSTTVSEGASP----GSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVI 386
Y+ V E SP GSV T N + S L +IN + G +
Sbjct: 455 SYTLFVRENNSPALPIGSVSATDRDSGTNAQVIYSLLPSQDPHLPLASLVSINADNGHLF 514
Query: 387 LRRSLDYETTSNYFYQVMVTDSIS---NDTASINISVEDVNEWEPRFRHPQYEFEXXXXX 443
RSLDYE + ++V TD S + A + + V D N+ P +P
Sbjct: 515 ALRSLDYEALQAFEFRVGATDRGSPALSSEALVRVLVLDANDNSPFVLYPLQNSSAPCTE 574
Query: 444 XXXXXXXXXXXXXXXVAHDGDAGTLA-LS---LAGQHARMFYINASGDLFLREEAIGNLN 499
VA DGD+G A LS L +F + A + +
Sbjct: 575 PLPRAAEPGYLVTKVVAVDGDSGQNAWLSYQLLKATEPGLFGVWAHNGEVRTARLLSERD 634
Query: 500 SSSLHLVATAIDSGIPPRQTS 520
++ LV D+G PPR +
Sbjct: 635 AAKQRLVVLVKDNGEPPRSAT 655
Score = 74.5 bits (175), Expect = 1e-12
Identities = 70/228 (30%), Positives = 101/228 (44%), Gaps = 18/228 (7%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPG-- 151
++V V DVNDNAP + Y + V E +DRD G ++ + Y++LP
Sbjct: 437 ITVLVSDVNDNAPAFTQTSYTLFVRENNSPALPIGSVSATDRDS-GTNAQVIYSLLPSQD 495
Query: 152 PHSEYLGFE--NELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDAD 209
PH N + + LD+E + F ++ D+GSP L S+ ++V VLDA+
Sbjct: 496 PHLPLASLVSINADNGHLFALRSLDYEALQAFEFRVGATDRGSPALSSEALVRVLVLDAN 555
Query: 210 DQNPKFTY------EHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYS-STGDH 262
D +P Y T LP AE G +T + A D D G NA L Y
Sbjct: 556 DNSPFVLYPLQNSSAPCTEPLPRAAEPGYLVT----KVVAVDGDSGQNAWLSYQLLKATE 611
Query: 263 KQLIVVNKDTGQVAATKQLIAELDPS-VTIVLKATQVDNPDRYALATL 309
L V G+V T +L++E D + +V+ P R A ATL
Sbjct: 612 PGLFGVWAHNGEV-RTARLLSERDAAKQRLVVLVKDNGEPPRSATATL 658
>AF152525-1|AAD43785.1| 871|Homo sapiens protocadherin gamma C4
short form protein protein.
Length = 871
Score = 85.0 bits (201), Expect = 1e-15
Identities = 91/352 (25%), Positives = 138/352 (39%), Gaps = 25/352 (7%)
Query: 96 VRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSE 155
V V DVNDNAP ++ + Y + V E+ SD D GP + + G +
Sbjct: 230 VSVLDVNDNAPAFQQSSYRISVLESAPAGMVLIQLNASDPDL-GPSGNVTF-YFSGHTPD 287
Query: 156 YLGFENELEPI---IVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQN 212
+ L P + + PLDFE+ N + +R +D GSP + +L+V +LD +D
Sbjct: 288 RVRNLFSLHPTTGKLTLLGPLDFESENYYEFDVRARDGGSPAMEQHCSLRVDLLDVNDNA 347
Query: 213 PKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDT 272
P T LP+ AE GT + IS D D G N + DH + +
Sbjct: 348 PYITVTSELGTLPESAEPGTVVAL----ISVQDPDSGSNGDVSL-RIPDHLPFALKSAFR 402
Query: 273 GQ--VAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQ 330
Q + L E S I++ A+ NP T+ F Q
Sbjct: 403 NQFSLVTAGPLDREAKSSYDIMVTASDAGNPPLSTHRTIFLNISDVNDNPP-----SFFQ 457
Query: 331 KQYSTTVSEGASPGSVLLTLTTVPQ----NTEFRESPLQFYVSDRSFLDKFAIN-NAGEV 385
+ + V E PG +L +L N S L+ D S ++N G V
Sbjct: 458 RSHEVFVPENNRPGDLLCSLAASDPDSGLNALISYSLLEPRNRDVSASSFISLNPQTGAV 517
Query: 386 ILRRSLDYETTSNYFYQVMVTDSIS---NDTASINISVEDVNEWEPRFRHPQ 434
RS DYE T ++V D + + T ++ + V D+N+ P P+
Sbjct: 518 HATRSFDYEQTQTLQFEVQARDRGNPPLSSTVTVRLFVLDLNDNAPAVLRPR 569
Score = 72.1 bits (169), Expect = 8e-12
Identities = 82/363 (22%), Positives = 142/363 (39%), Gaps = 22/363 (6%)
Query: 85 TTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSAL 144
T P + V + DVND+AP++ + + E D D G +S
Sbjct: 110 TEGPLEMYRAEVEIVDVNDHAPRFPRQQLDLEIGEAAPPGQRFPLEKAQDADV-GSNSIS 168
Query: 145 HYAVLPGPHSEY---LGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTL 201
Y + H + L P ++++KPLD E +++ + L D G+PP L
Sbjct: 169 SYRLSSNEHFALDVKKRSDGSLVPELLLEKPLDREKQSDYRLVLTAVDGGNPPRSGTAEL 228
Query: 202 QVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGD 261
+V+VLD +D P F Y + + A G L ++A+D DLG + + + +G
Sbjct: 229 RVSVLDVNDNAPAFQQSSYRISVLESAPAGMVLI----QLNASDPDLGPSGNVTFYFSGH 284
Query: 262 H----KQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXX 317
+ L ++ TG++ L E + ++A +P +L
Sbjct: 285 TPDRVRNLFSLHPTTGKLTLLGPLDFESENYYEFDVRARDGGSPAMEQHCSLRVDLLDVN 344
Query: 318 XXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDR-SFLDK 376
T T+ E A PG+V + L +V + + D F K
Sbjct: 345 DNAP-----YITVTSELGTLPESAEPGTV-VALISVQDPDSGSNGDVSLRIPDHLPFALK 398
Query: 377 FAINNAGEVILRRSLDYETTSNYFYQVMVTDSIS---NDTASINISVEDVNEWEPRFRHP 433
A N ++ LD E S+Y V +D+ + + +I +++ DVN+ P F
Sbjct: 399 SAFRNQFSLVTAGPLDREAKSSYDIMVTASDAGNPPLSTHRTIFLNISDVNDNPPSFFQR 458
Query: 434 QYE 436
+E
Sbjct: 459 SHE 461
Score = 64.5 bits (150), Expect = 2e-09
Identities = 67/293 (22%), Positives = 117/293 (39%), Gaps = 15/293 (5%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQE--KGAAVGIVPGSKNLTLLRALDREEK 68
+ E G+++ +SV S GD++LR+ + A +L LDRE K
Sbjct: 359 LPESAEPGTVVALISVQDPDSGSNGDVSLRIPDHLPFALKSAFRNQFSLVTAGPLDREAK 418
Query: 69 IGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXX 128
S+ + V S + + + DVNDN P + + V V E
Sbjct: 419 ---SSYDIMVTASDAGNPPLSTHRTIFLNISDVNDNPPSFFQRSHEVFVPENNRPGDLLC 475
Query: 129 XXXXSDRDQPGPHSALHYAVLPGPHSEYLGFEN--ELEP---IIVVKKPLDFETVNNFTI 183
SD D G ++ + Y++L P + + + L P + + D+E
Sbjct: 476 SLAASDPDS-GLNALISYSLLE-PRNRDVSASSFISLNPQTGAVHATRSFDYEQTQTLQF 533
Query: 184 KLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYT--ALLPDDAEEGTFLTTSPGPI 241
+++ +D+G+PPL S T+++ VLD +D P +L P +
Sbjct: 534 EVQARDRGNPPLSSTVTVRLFVLDLNDNAPAVLRPRARPGSLCPQALPPSVGAGHLITKV 593
Query: 242 SAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVL 293
+A D D G NA + Y L V++ G+V + A+L P +++
Sbjct: 594 TAVDLDSGYNAWVSYQLLEAPDPSLFAVSRYAGEVRTAVPIPADLPPQKLVIV 646
>AF152505-1|AAD43766.1| 837|Homo sapiens protocadherin gamma A11
short form protein protein.
Length = 837
Score = 85.0 bits (201), Expect = 1e-15
Identities = 102/440 (23%), Positives = 173/440 (39%), Gaps = 28/440 (6%)
Query: 9 FFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAA--VGIVPGSKNLTLLRALDR 65
+ + E+T GS +G +S + G +L +R+ +G + P S +L +DR
Sbjct: 34 YSVPEETEKGSFVGNISKDLGLEPRELAKRGVRIVSRGKTQLFAVNPRSGSLITAGRIDR 93
Query: 66 EEKIGP-SNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXX 124
EE S+ ++N+ D + V V + D+NDNAP ++ ++VSE
Sbjct: 94 EELCETVSSCFLNMEL---LVEDTLKIYGVEVEIIDINDNAPSFQEDEVEIKVSEHAIPG 150
Query: 125 XXXXXXXXSDRDQPGPHSALHYAVLPGPHS--EYLG-FENELEPIIVVKKPLDFETVNNF 181
D D G +S Y + P + + G + P +V++ LD E
Sbjct: 151 ARFALPNARDPDV-GVNSLQSYQLSPNNYFSLQLRGRTDGAKNPELVLEGSLDREKEAAH 209
Query: 182 TIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPI 241
+ L D G P ++V VLD +D P FT Y +P++ GT + +
Sbjct: 210 LLLLTALDGGDPIRKGAVPIRVVVLDVNDHIPMFTQSVYRVSVPENISSGTRVLM----V 265
Query: 242 SAADQDLGINAPLQYS---STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQV 298
+A D D GIN + YS ++ ++ TG+V Q+ LD ++
Sbjct: 266 NATDPDEGINGEVMYSFRNMESKASEIFQLDSQTGEV----QVRGSLD-FEKYRFYEMEI 320
Query: 299 DNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTE 358
D L T + T ++ E + PG+V+ L Q++
Sbjct: 321 QGQDGGGLFTTTTMLITVVDVNDNAPEITITSS--INSILENSPPGTVIALLNVQDQDSG 378
Query: 359 FRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSISNDTAS--- 415
F + F + N ++I R LD E +Y + TD S ++
Sbjct: 379 ENGQVSCFIPNHLPFKLEKTYGNYYKLITSRVLDRELVQSYNITLTATDQGSPPLSAETH 438
Query: 416 INISVEDVNEWEPRFRHPQY 435
+ ++V D N+ P F H Y
Sbjct: 439 VWLNVADDNDNPPVFPHSSY 458
Score = 63.7 bits (148), Expect = 3e-09
Identities = 75/313 (23%), Positives = 122/313 (38%), Gaps = 22/313 (7%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEK-GAAVGIVPGSK-NLTLLRALDREEK 68
I E++P G++I L+V S + G ++ + + G+ L R LDRE
Sbjct: 357 ILENSPPGTVIALLNVQDQDSGENGQVSCFIPNHLPFKLEKTYGNYYKLITSRVLDRELV 416
Query: 69 IGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXX 128
+ + + + + S V + V D NDN P + + Y+ + E
Sbjct: 417 ---QSYNITLTATDQGSPPLSAETHVWLNVADDNDNPPVFPHSSYSAYIPENNPRGASIF 473
Query: 129 XXXXSDRDQPG----PHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIK 184
D D +S V P S Y+ N ++ + D+E + ++
Sbjct: 474 SVTALDPDSKQNALVTYSLTDDTVQGVPLSSYVSI-NSNTGVLYALQSFDYEQFRDLELR 532
Query: 185 LRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFL---TTSPG-- 239
+ +D G PPL S+ +L + VLD +D P+ Y LP D G L + PG
Sbjct: 533 VIARDSGDPPLSSNVSLSLFVLDQNDNAPEILY----PALPTDGSTGVELAPRSAEPGYL 588
Query: 240 --PISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKAT 296
+ A D+D G NA L Y L V + TG+V + L+ ++V+
Sbjct: 589 VTKVVAVDKDSGQNAWLSYRLLKASEPGLFAVGEHTGEVRTARALLDRDALKQSLVVAVQ 648
Query: 297 QVDNPDRYALATL 309
P A TL
Sbjct: 649 DHGQPPLSATVTL 661
Score = 63.3 bits (147), Expect = 4e-09
Identities = 54/190 (28%), Positives = 84/190 (44%), Gaps = 16/190 (8%)
Query: 96 VRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRD--QPGPHSALHYAVLPGPH 153
+ V DVNDNAP+ + E D+D + G S LP
Sbjct: 336 ITVVDVNDNAPEITITSSINSILENSPPGTVIALLNVQDQDSGENGQVSCFIPNHLPFKL 395
Query: 154 SEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNP 213
+ G +L + + LD E V ++ I L DQGSPPL ++T + + V D +D P
Sbjct: 396 EKTYGNYYKL----ITSRVLDRELVQSYNITLTATDQGSPPLSAETHVWLNVADDNDNPP 451
Query: 214 KFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQ------LIV 267
F + Y+A +P++ G + + ++A D D NA + YS T D Q +
Sbjct: 452 VFPHSSYSAYIPENNPRGASIFS----VTALDPDSKQNALVTYSLTDDTVQGVPLSSYVS 507
Query: 268 VNKDTGQVAA 277
+N +TG + A
Sbjct: 508 INSNTGVLYA 517
Score = 34.7 bits (76), Expect = 1.5
Identities = 51/217 (23%), Positives = 88/217 (40%), Gaps = 23/217 (10%)
Query: 8 SFFISEDTPIG-SIIGTLSVNGDPSED------LGDITLRLQEKGAAVGIVPGSKNLTLL 60
S +I E+ P G SI +++ D ++ L D T++ + V I + L L
Sbjct: 459 SAYIPENNPRGASIFSVTALDPDSKQNALVTYSLTDDTVQGVPLSSYVSINSNTGVLYAL 518
Query: 61 RALDREEKIGPSNVYVNVRCDRRRTTDP--SFVIPVSVRVWDVNDNAPQ-------WEGA 111
++ D E+ + +R R + DP S + +S+ V D NDNAP+ +G+
Sbjct: 519 QSFDYEQFRD-----LELRVIARDSGDPPLSSNVSLSLFVLDQNDNAPEILYPALPTDGS 573
Query: 112 PYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKK 171
+ D+D G ++ L Y +L + +
Sbjct: 574 TGVELAPRSAEPGYLVTKVVAVDKDS-GQNAWLSYRLLKASEPGLFAVGEHTGEVRTARA 632
Query: 172 PLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDA 208
LD + + ++ + VQD G PPL + TL V V D+
Sbjct: 633 LLDRDALKQ-SLVVAVQDHGQPPLSATVTLTVAVADS 668
>AF152504-1|AAD43765.1| 750|Homo sapiens protocadherin gamma A11
protein.
Length = 750
Score = 85.0 bits (201), Expect = 1e-15
Identities = 102/440 (23%), Positives = 173/440 (39%), Gaps = 28/440 (6%)
Query: 9 FFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAA--VGIVPGSKNLTLLRALDR 65
+ + E+T GS +G +S + G +L +R+ +G + P S +L +DR
Sbjct: 34 YSVPEETEKGSFVGNISKDLGLEPRELAKRGVRIVSRGKTQLFAVNPRSGSLITAGRIDR 93
Query: 66 EEKIGP-SNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXX 124
EE S+ ++N+ D + V V + D+NDNAP ++ ++VSE
Sbjct: 94 EELCETVSSCFLNMEL---LVEDTLKIYGVEVEIIDINDNAPSFQEDEVEIKVSEHAIPG 150
Query: 125 XXXXXXXXSDRDQPGPHSALHYAVLPGPHS--EYLG-FENELEPIIVVKKPLDFETVNNF 181
D D G +S Y + P + + G + P +V++ LD E
Sbjct: 151 ARFALPNARDPDV-GVNSLQSYQLSPNNYFSLQLRGRTDGAKNPELVLEGSLDREKEAAH 209
Query: 182 TIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPI 241
+ L D G P ++V VLD +D P FT Y +P++ GT + +
Sbjct: 210 LLLLTALDGGDPIRKGAVPIRVVVLDVNDHIPMFTQSVYRVSVPENISSGTRVLM----V 265
Query: 242 SAADQDLGINAPLQYS---STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQV 298
+A D D GIN + YS ++ ++ TG+V Q+ LD ++
Sbjct: 266 NATDPDEGINGEVMYSFRNMESKASEIFQLDSQTGEV----QVRGSLD-FEKYRFYEMEI 320
Query: 299 DNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTE 358
D L T + T ++ E + PG+V+ L Q++
Sbjct: 321 QGQDGGGLFTTTTMLITVVDVNDNAPEITITSS--INSILENSPPGTVIALLNVQDQDSG 378
Query: 359 FRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSISNDTAS--- 415
F + F + N ++I R LD E +Y + TD S ++
Sbjct: 379 ENGQVSCFIPNHLPFKLEKTYGNYYKLITSRVLDRELVQSYNITLTATDQGSPPLSAETH 438
Query: 416 INISVEDVNEWEPRFRHPQY 435
+ ++V D N+ P F H Y
Sbjct: 439 VWLNVADDNDNPPVFPHSSY 458
Score = 63.3 bits (147), Expect = 4e-09
Identities = 54/190 (28%), Positives = 84/190 (44%), Gaps = 16/190 (8%)
Query: 96 VRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRD--QPGPHSALHYAVLPGPH 153
+ V DVNDNAP+ + E D+D + G S LP
Sbjct: 336 ITVVDVNDNAPEITITSSINSILENSPPGTVIALLNVQDQDSGENGQVSCFIPNHLPFKL 395
Query: 154 SEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNP 213
+ G +L + + LD E V ++ I L DQGSPPL ++T + + V D +D P
Sbjct: 396 EKTYGNYYKL----ITSRVLDRELVQSYNITLTATDQGSPPLSAETHVWLNVADDNDNPP 451
Query: 214 KFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQ------LIV 267
F + Y+A +P++ G + + ++A D D NA + YS T D Q +
Sbjct: 452 VFPHSSYSAYIPENNPRGASIFS----VTALDPDSKQNALVTYSLTDDTVQGVPLSSYVS 507
Query: 268 VNKDTGQVAA 277
+N +TG + A
Sbjct: 508 INSNTGVLYA 517
Score = 59.3 bits (137), Expect = 6e-08
Identities = 69/280 (24%), Positives = 111/280 (39%), Gaps = 22/280 (7%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEK-GAAVGIVPGSK-NLTLLRALDREEK 68
I E++P G++I L+V S + G ++ + + G+ L R LDRE
Sbjct: 357 ILENSPPGTVIALLNVQDQDSGENGQVSCFIPNHLPFKLEKTYGNYYKLITSRVLDRELV 416
Query: 69 IGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXX 128
+ + + + + S V + V D NDN P + + Y+ + E
Sbjct: 417 ---QSYNITLTATDQGSPPLSAETHVWLNVADDNDNPPVFPHSSYSAYIPENNPRGASIF 473
Query: 129 XXXXSDRDQPG----PHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIK 184
D D +S V P S Y+ N ++ + D+E + ++
Sbjct: 474 SVTALDPDSKQNALVTYSLTDDTVQGVPLSSYVSI-NSNTGVLYALQSFDYEQFRDLELR 532
Query: 185 LRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFL---TTSPG-- 239
+ +D G PPL S+ +L + VLD +D P+ Y LP D G L + PG
Sbjct: 533 VIARDSGDPPLSSNVSLSLFVLDQNDNAPEILY----PALPTDGSTGVELAPRSAEPGYL 588
Query: 240 --PISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVA 276
+ A D+D G NA L Y L V + TG+ A
Sbjct: 589 VTKVVAVDKDSGQNAWLSYRLLKASEPGLFAVGEHTGEQA 628
>AF152500-1|AAD43761.1| 793|Homo sapiens protocadherin beta 7
protein.
Length = 793
Score = 85.0 bits (201), Expect = 1e-15
Identities = 93/441 (21%), Positives = 185/441 (41%), Gaps = 31/441 (7%)
Query: 9 FFISEDTPIGSIIGTLSVNGDPSEDLGDITLR----LQEKGAAVGIVPG-SKNLTLLRAL 63
+F++E+T G+ + L+ D +G++ R + ++ + ++ + +L L L
Sbjct: 33 YFVAEETERGTFLTNLAK--DLGLGVGELRARGTRIVSDQNMQILLLSSLTGDLLLNEKL 90
Query: 64 DREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXX 123
DREE GP V + P + + V D+ND+AP + ++++ E+
Sbjct: 91 DREELCGPREPCVLPF--QLLLEKPFQIFRAELWVRDINDHAPVFLDREISLKILESTTP 148
Query: 124 XXXXXXXXXSDRDQPGPHSALHYAVLPGPH---SEYLGFENELEPIIVVKKPLDFETVNN 180
D D G +S +Y + P + + + E + P +V+ + LD E +
Sbjct: 149 GAAFLLESAQDSDV-GTNSLSNYTISPNAYFHINVHDSGEGNIYPELVLNQVLDREEIPE 207
Query: 181 FTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGP 240
F++ L D GSPP +++ VLD +D P F Y +P+++ G+ + +
Sbjct: 208 FSLTLTALDGGSPPRSGTALVRILVLDVNDNAPDFVRSLYKVQVPENSPVGSMVVS---- 263
Query: 241 ISAADQDLGINAPLQYSSTGDHKQLI---VVNKDTGQVAATKQLIAELDPSVTIVLKATQ 297
+SA D D G N + Y+ + ++++ +N +G + QL E + T+ ++A
Sbjct: 264 VSARDLDTGSNGEIAYAFSYATERILKTFQINPTSGSLHLKAQLDYEAIQTYTLTIQAK- 322
Query: 298 VDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNT 357
D T+ + ++ ++E SP +V+ +++
Sbjct: 323 -DGGGLSGKCTVVVDVTDINDNRP-----ELLLSSLTSPIAEN-SPETVVAVFRIRDRDS 375
Query: 358 EFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSIS---NDTA 414
+ D F+ K ++ N ++ + LD E + Y + VTD +
Sbjct: 376 GNNGKTVCSIQDDVPFILKPSVENFYTLVTEKPLDRERNTEYNITITVTDLGTPRLKTEH 435
Query: 415 SINISVEDVNEWEPRFRHPQY 435
+I + V DVN+ P F Y
Sbjct: 436 NITVLVSDVNDNAPAFTQTSY 456
Score = 74.5 bits (175), Expect = 1e-12
Identities = 105/441 (23%), Positives = 159/441 (36%), Gaps = 27/441 (6%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
V + V DVNDNAP + + Y V+V E D D G + + YA
Sbjct: 228 VRILVLDVNDNAPDFVRSLYKVQVPENSPVGSMVVSVSARDLDT-GSNGEIAYAFSYATE 286
Query: 154 SEYLGFE-NELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQN 212
F+ N + +K LD+E + +T+ ++ +D G L T+ V V D +D
Sbjct: 287 RILKTFQINPTSGSLHLKAQLDYEAIQTYTLTIQAKDGGG--LSGKCTVVVDVTDINDNR 344
Query: 213 PKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDT 272
P+ T+ + +++ E T D+D G N S D ++ + +
Sbjct: 345 PELLLSSLTSPIAENSPE-----TVVAVFRIRDRDSGNNGKTVCSIQDDVPFILKPSVEN 399
Query: 273 GQVAAT-KQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQK 331
T K L E + I + T + P L T FTQ
Sbjct: 400 FYTLVTEKPLDRERNTEYNITITVTDLGTP---RLKTEHNITVLVSDVNDNAPA--FTQT 454
Query: 332 QYSTTVSEGASP----GSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVI 386
Y+ V E SP GSV T N + S L +IN + G +
Sbjct: 455 SYTLFVRENNSPALPIGSVSATDRDSGTNAQVIYSLLPSQDPHLPLASLVSINADNGHLF 514
Query: 387 LRRSLDYETTSNYFYQVMVTDSIS---NDTASINISVEDVNEWEPRFRHPQYEFEXXXXX 443
RSLDYE + ++V TD S + A + + V D N+ P +P
Sbjct: 515 ALRSLDYEALQAFEFRVGATDRGSPALSSEALVRVLVLDANDNSPFVLYPLQNSSAPCTE 574
Query: 444 XXXXXXXXXXXXXXXVAHDGDAGTLA-LS---LAGQHARMFYINASGDLFLREEAIGNLN 499
VA DGD+G A LS L +F + A + +
Sbjct: 575 PLPRAAEPGYLVTKVVAVDGDSGQNAWLSYQLLKATEPGLFGVWAHNGEVRTARLLSERD 634
Query: 500 SSSLHLVATAIDSGIPPRQTS 520
++ LV D+G PPR +
Sbjct: 635 AAKQRLVVLVKDNGEPPRSAT 655
Score = 74.5 bits (175), Expect = 1e-12
Identities = 70/228 (30%), Positives = 101/228 (44%), Gaps = 18/228 (7%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPG-- 151
++V V DVNDNAP + Y + V E +DRD G ++ + Y++LP
Sbjct: 437 ITVLVSDVNDNAPAFTQTSYTLFVRENNSPALPIGSVSATDRDS-GTNAQVIYSLLPSQD 495
Query: 152 PHSEYLGFE--NELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDAD 209
PH N + + LD+E + F ++ D+GSP L S+ ++V VLDA+
Sbjct: 496 PHLPLASLVSINADNGHLFALRSLDYEALQAFEFRVGATDRGSPALSSEALVRVLVLDAN 555
Query: 210 DQNPKFTY------EHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYS-STGDH 262
D +P Y T LP AE G +T + A D D G NA L Y
Sbjct: 556 DNSPFVLYPLQNSSAPCTEPLPRAAEPGYLVT----KVVAVDGDSGQNAWLSYQLLKATE 611
Query: 263 KQLIVVNKDTGQVAATKQLIAELDPS-VTIVLKATQVDNPDRYALATL 309
L V G+V T +L++E D + +V+ P R A ATL
Sbjct: 612 PGLFGVWAHNGEV-RTARLLSERDAAKQRLVVLVKDNGEPPRSATATL 658
>AF152338-1|AAD43732.1| 938|Homo sapiens protocadherin gamma C4
protein.
Length = 938
Score = 85.0 bits (201), Expect = 1e-15
Identities = 91/352 (25%), Positives = 138/352 (39%), Gaps = 25/352 (7%)
Query: 96 VRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSE 155
V V DVNDNAP ++ + Y + V E+ SD D GP + + G +
Sbjct: 230 VSVLDVNDNAPAFQQSSYRISVLESAPAGMVLIQLNASDPDL-GPSGNVTF-YFSGHTPD 287
Query: 156 YLGFENELEPI---IVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQN 212
+ L P + + PLDFE+ N + +R +D GSP + +L+V +LD +D
Sbjct: 288 RVRNLFSLHPTTGKLTLLGPLDFESENYYEFDVRARDGGSPAMEQHCSLRVDLLDVNDNA 347
Query: 213 PKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDT 272
P T LP+ AE GT + IS D D G N + DH + +
Sbjct: 348 PYITVTSELGTLPESAEPGTVVAL----ISVQDPDSGSNGDVSL-RIPDHLPFALKSAFR 402
Query: 273 GQ--VAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQ 330
Q + L E S I++ A+ NP T+ F Q
Sbjct: 403 NQFSLVTAGPLDREAKSSYDIMVTASDAGNPPLSTHRTIFLNISDVNDNPP-----SFFQ 457
Query: 331 KQYSTTVSEGASPGSVLLTLTTVPQ----NTEFRESPLQFYVSDRSFLDKFAIN-NAGEV 385
+ + V E PG +L +L N S L+ D S ++N G V
Sbjct: 458 RSHEVFVPENNRPGDLLCSLAASDPDSGLNALISYSLLEPRNRDVSASSFISLNPQTGAV 517
Query: 386 ILRRSLDYETTSNYFYQVMVTDSIS---NDTASINISVEDVNEWEPRFRHPQ 434
RS DYE T ++V D + + T ++ + V D+N+ P P+
Sbjct: 518 HATRSFDYEQTQTLQFEVQARDRGNPPLSSTVTVRLFVLDLNDNAPAVLRPR 569
Score = 72.1 bits (169), Expect = 8e-12
Identities = 82/363 (22%), Positives = 142/363 (39%), Gaps = 22/363 (6%)
Query: 85 TTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSAL 144
T P + V + DVND+AP++ + + E D D G +S
Sbjct: 110 TEGPLEMYRAEVEIVDVNDHAPRFPRQQLDLEIGEAAPPGQRFPLEKAQDADV-GSNSIS 168
Query: 145 HYAVLPGPHSEY---LGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTL 201
Y + H + L P ++++KPLD E +++ + L D G+PP L
Sbjct: 169 SYRLSSNEHFALDVKKRSDGSLVPELLLEKPLDREKQSDYRLVLTAVDGGNPPRSGTAEL 228
Query: 202 QVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGD 261
+V+VLD +D P F Y + + A G L ++A+D DLG + + + +G
Sbjct: 229 RVSVLDVNDNAPAFQQSSYRISVLESAPAGMVLI----QLNASDPDLGPSGNVTFYFSGH 284
Query: 262 H----KQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXX 317
+ L ++ TG++ L E + ++A +P +L
Sbjct: 285 TPDRVRNLFSLHPTTGKLTLLGPLDFESENYYEFDVRARDGGSPAMEQHCSLRVDLLDVN 344
Query: 318 XXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDR-SFLDK 376
T T+ E A PG+V + L +V + + D F K
Sbjct: 345 DNAP-----YITVTSELGTLPESAEPGTV-VALISVQDPDSGSNGDVSLRIPDHLPFALK 398
Query: 377 FAINNAGEVILRRSLDYETTSNYFYQVMVTDSIS---NDTASINISVEDVNEWEPRFRHP 433
A N ++ LD E S+Y V +D+ + + +I +++ DVN+ P F
Sbjct: 399 SAFRNQFSLVTAGPLDREAKSSYDIMVTASDAGNPPLSTHRTIFLNISDVNDNPPSFFQR 458
Query: 434 QYE 436
+E
Sbjct: 459 SHE 461
Score = 64.5 bits (150), Expect = 2e-09
Identities = 67/293 (22%), Positives = 117/293 (39%), Gaps = 15/293 (5%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQE--KGAAVGIVPGSKNLTLLRALDREEK 68
+ E G+++ +SV S GD++LR+ + A +L LDRE K
Sbjct: 359 LPESAEPGTVVALISVQDPDSGSNGDVSLRIPDHLPFALKSAFRNQFSLVTAGPLDREAK 418
Query: 69 IGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXX 128
S+ + V S + + + DVNDN P + + V V E
Sbjct: 419 ---SSYDIMVTASDAGNPPLSTHRTIFLNISDVNDNPPSFFQRSHEVFVPENNRPGDLLC 475
Query: 129 XXXXSDRDQPGPHSALHYAVLPGPHSEYLGFEN--ELEP---IIVVKKPLDFETVNNFTI 183
SD D G ++ + Y++L P + + + L P + + D+E
Sbjct: 476 SLAASDPDS-GLNALISYSLLE-PRNRDVSASSFISLNPQTGAVHATRSFDYEQTQTLQF 533
Query: 184 KLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYT--ALLPDDAEEGTFLTTSPGPI 241
+++ +D+G+PPL S T+++ VLD +D P +L P +
Sbjct: 534 EVQARDRGNPPLSSTVTVRLFVLDLNDNAPAVLRPRARPGSLCPQALPPSVGAGHLITKV 593
Query: 242 SAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVL 293
+A D D G NA + Y L V++ G+V + A+L P +++
Sbjct: 594 TAVDLDSGYNAWVSYQLLEAPDPSLFAVSRYAGEVRTAVPIPADLPPQKLVIV 646
>AF152320-1|AAD43714.1| 935|Homo sapiens protocadherin gamma A11
protein.
Length = 935
Score = 85.0 bits (201), Expect = 1e-15
Identities = 102/440 (23%), Positives = 173/440 (39%), Gaps = 28/440 (6%)
Query: 9 FFISEDTPIGSIIGTLSVN-GDPSEDLGDITLRLQEKGAA--VGIVPGSKNLTLLRALDR 65
+ + E+T GS +G +S + G +L +R+ +G + P S +L +DR
Sbjct: 34 YSVPEETEKGSFVGNISKDLGLEPRELAKRGVRIVSRGKTQLFAVNPRSGSLITAGRIDR 93
Query: 66 EEKIGP-SNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXX 124
EE S+ ++N+ D + V V + D+NDNAP ++ ++VSE
Sbjct: 94 EELCETVSSCFLNMEL---LVEDTLKIYGVEVEIIDINDNAPSFQEDEVEIKVSEHAIPG 150
Query: 125 XXXXXXXXSDRDQPGPHSALHYAVLPGPHS--EYLG-FENELEPIIVVKKPLDFETVNNF 181
D D G +S Y + P + + G + P +V++ LD E
Sbjct: 151 ARFALPNARDPDV-GVNSLQSYQLSPNNYFSLQLRGRTDGAKNPELVLEGSLDREKEAAH 209
Query: 182 TIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPI 241
+ L D G P ++V VLD +D P FT Y +P++ GT + +
Sbjct: 210 LLLLTALDGGDPIRKGAVPIRVVVLDVNDHIPMFTQSVYRVSVPENISSGTRVLM----V 265
Query: 242 SAADQDLGINAPLQYS---STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQV 298
+A D D GIN + YS ++ ++ TG+V Q+ LD ++
Sbjct: 266 NATDPDEGINGEVMYSFRNMESKASEIFQLDSQTGEV----QVRGSLD-FEKYRFYEMEI 320
Query: 299 DNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTE 358
D L T + T ++ E + PG+V+ L Q++
Sbjct: 321 QGQDGGGLFTTTTMLITVVDVNDNAPEITITSS--INSILENSPPGTVIALLNVQDQDSG 378
Query: 359 FRESPLQFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDSISNDTAS--- 415
F + F + N ++I R LD E +Y + TD S ++
Sbjct: 379 ENGQVSCFIPNHLPFKLEKTYGNYYKLITSRVLDRELVQSYNITLTATDQGSPPLSAETH 438
Query: 416 INISVEDVNEWEPRFRHPQY 435
+ ++V D N+ P F H Y
Sbjct: 439 VWLNVADDNDNPPVFPHSSY 458
Score = 63.7 bits (148), Expect = 3e-09
Identities = 75/313 (23%), Positives = 122/313 (38%), Gaps = 22/313 (7%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEK-GAAVGIVPGSK-NLTLLRALDREEK 68
I E++P G++I L+V S + G ++ + + G+ L R LDRE
Sbjct: 357 ILENSPPGTVIALLNVQDQDSGENGQVSCFIPNHLPFKLEKTYGNYYKLITSRVLDRELV 416
Query: 69 IGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXX 128
+ + + + + S V + V D NDN P + + Y+ + E
Sbjct: 417 ---QSYNITLTATDQGSPPLSAETHVWLNVADDNDNPPVFPHSSYSAYIPENNPRGASIF 473
Query: 129 XXXXSDRDQPG----PHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIK 184
D D +S V P S Y+ N ++ + D+E + ++
Sbjct: 474 SVTALDPDSKQNALVTYSLTDDTVQGVPLSSYVSI-NSNTGVLYALQSFDYEQFRDLELR 532
Query: 185 LRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFL---TTSPG-- 239
+ +D G PPL S+ +L + VLD +D P+ Y LP D G L + PG
Sbjct: 533 VIARDSGDPPLSSNVSLSLFVLDQNDNAPEILY----PALPTDGSTGVELAPRSAEPGYL 588
Query: 240 --PISAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKAT 296
+ A D+D G NA L Y L V + TG+V + L+ ++V+
Sbjct: 589 VTKVVAVDKDSGQNAWLSYRLLKASEPGLFAVGEHTGEVRTARALLDRDALKQSLVVAVQ 648
Query: 297 QVDNPDRYALATL 309
P A TL
Sbjct: 649 DHGQPPLSATVTL 661
Score = 63.3 bits (147), Expect = 4e-09
Identities = 54/190 (28%), Positives = 84/190 (44%), Gaps = 16/190 (8%)
Query: 96 VRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRD--QPGPHSALHYAVLPGPH 153
+ V DVNDNAP+ + E D+D + G S LP
Sbjct: 336 ITVVDVNDNAPEITITSSINSILENSPPGTVIALLNVQDQDSGENGQVSCFIPNHLPFKL 395
Query: 154 SEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNP 213
+ G +L + + LD E V ++ I L DQGSPPL ++T + + V D +D P
Sbjct: 396 EKTYGNYYKL----ITSRVLDRELVQSYNITLTATDQGSPPLSAETHVWLNVADDNDNPP 451
Query: 214 KFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQ------LIV 267
F + Y+A +P++ G + + ++A D D NA + YS T D Q +
Sbjct: 452 VFPHSSYSAYIPENNPRGASIFS----VTALDPDSKQNALVTYSLTDDTVQGVPLSSYVS 507
Query: 268 VNKDTGQVAA 277
+N +TG + A
Sbjct: 508 INSNTGVLYA 517
Score = 34.7 bits (76), Expect = 1.5
Identities = 51/217 (23%), Positives = 88/217 (40%), Gaps = 23/217 (10%)
Query: 8 SFFISEDTPIG-SIIGTLSVNGDPSED------LGDITLRLQEKGAAVGIVPGSKNLTLL 60
S +I E+ P G SI +++ D ++ L D T++ + V I + L L
Sbjct: 459 SAYIPENNPRGASIFSVTALDPDSKQNALVTYSLTDDTVQGVPLSSYVSINSNTGVLYAL 518
Query: 61 RALDREEKIGPSNVYVNVRCDRRRTTDP--SFVIPVSVRVWDVNDNAPQ-------WEGA 111
++ D E+ + +R R + DP S + +S+ V D NDNAP+ +G+
Sbjct: 519 QSFDYEQFRD-----LELRVIARDSGDPPLSSNVSLSLFVLDQNDNAPEILYPALPTDGS 573
Query: 112 PYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKK 171
+ D+D G ++ L Y +L + +
Sbjct: 574 TGVELAPRSAEPGYLVTKVVAVDKDS-GQNAWLSYRLLKASEPGLFAVGEHTGEVRTARA 632
Query: 172 PLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDA 208
LD + + ++ + VQD G PPL + TL V V D+
Sbjct: 633 LLDRDALKQ-SLVVAVQDHGQPPLSATVTLTVAVADS 668
>AB035303-1|BAA87417.1| 788|Homo sapiens cadherin-10 protein.
Length = 788
Score = 85.0 bits (201), Expect = 1e-15
Identities = 107/423 (25%), Positives = 179/423 (42%), Gaps = 39/423 (9%)
Query: 32 EDLGDITLR--LQEKGAAVGIVPGSK--NLTLLRALDREEKIGPSNVYVNVRCDRRRTTD 87
+D GD +L+ L GA + K ++ R +DREEK + + + RRT
Sbjct: 82 QDKGDGSLKYILSGDGAGTLFIIDEKTGDIHATRRIDREEK---AFYTLRAQAINRRTLR 138
Query: 88 PSFVIPVS---VRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQP--GPHS 142
P V P S +++ D+NDN P + Y V E +D D P G +
Sbjct: 139 P--VEPESEFVIKIHDINDNEPTFPEEIYTASVPEMSVVGTSVVQVTATDADDPSYGNSA 196
Query: 143 ALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSP--PLYSDTT 200
+ Y++L G Y E E I ++ E + + ++ +D G L TT
Sbjct: 197 RVIYSILQG--QPYFSVEPETGIIRTALPNMNRENREQYQVVIQAKDMGGQMGGLSGTTT 254
Query: 201 LQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYS-ST 259
+ +T+ D +D P+F + + + GT + G + A D D G NA ++Y
Sbjct: 255 VNITLTDVNDNPPRFPQNTIHLRVLESSPVGTAI----GSVKATDADTGKNAEVEYRIID 310
Query: 260 GDHKQL--IVVNKDT--GQVAATKQLIAELDPSVTIVLKA--TQVDNPDRYALATLXXXX 313
GD + IV KDT G + K L E T+ ++A T VD P Y L
Sbjct: 311 GDGTDMFDIVTEKDTQEGIITVKKPLDYESRRLYTLKVEAENTHVD-PRFYYLGPFKDTT 369
Query: 314 XXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSF 373
F++ Y V E G+++ T+ + ++ + SP++F + +
Sbjct: 370 IVKISIEDVDEPPVFSRSSYLFEVHEDIEVGTIIGTV--MARDPDSISSPIRFSLDRHTD 427
Query: 374 LDK-FAINNA-GEVILRRSLDYETTSNYFYQVMVTDSISN--DTASINISVE--DVNEWE 427
LD+ F I++ G + + LD E S + ++ I+N +T + + V DVN+
Sbjct: 428 LDRIFNIHSGNGSLYTSKPLDRE-LSQWHNLTVIAAEINNPKETTRVAVFVRILDVNDNA 486
Query: 428 PRF 430
P+F
Sbjct: 487 PQF 489
Score = 51.2 bits (117), Expect = 2e-05
Identities = 54/230 (23%), Positives = 83/230 (36%), Gaps = 9/230 (3%)
Query: 9 FFISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQ---EKGAAVGIVPGSKNLTLLRALDR 65
F + ED +G+IIGT+ DP I L + I G+ +L + LDR
Sbjct: 391 FEVHEDIEVGTIIGTVMAR-DPDSISSPIRFSLDRHTDLDRIFNIHSGNGSLYTSKPLDR 449
Query: 66 EEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXX 125
E + + + + T + V VR+ DVNDNAPQ+ Y V E
Sbjct: 450 ELSQWHNLTVIAAEINNPKETTR---VAVFVRILDVNDNAPQF-AVFYDTFVCENARPGQ 505
Query: 126 XXXXXXXSDRDQP-GPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIK 184
D+D P G P+ E+ I+ K + ++ + +
Sbjct: 506 LIQTISAVDKDDPLGGQKFFFSLAAVNPNFTVQDNEDNTARILTRKNGFNRHEISTYLLP 565
Query: 185 LRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFL 234
+ + D P S TL + V D Q + LLP G +
Sbjct: 566 VVISDNDYPIQSSTGTLTIRVCACDSQGNMQSCSAEALLLPAGLSTGALI 615
>D21255-1|BAA04799.1| 693|Homo sapiens OB-cadherin-2 protein.
Length = 693
Score = 84.6 bits (200), Expect = 1e-15
Identities = 108/453 (23%), Positives = 179/453 (39%), Gaps = 32/453 (7%)
Query: 3 GGAVESFFISEDT--PIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSK--NLT 58
G FF+ E+ P ++G L + D + G+I L +GA V K N+
Sbjct: 54 GWVWNQFFVIEEYTGPDPVLVGRLHSDIDSGD--GNIKYILSGEGAGTIFVIDDKSGNIH 111
Query: 59 LLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVS 118
+ LDREE+ + + V D R +P V V+ D+NDN P++ Y V
Sbjct: 112 ATKTLDREERAQYTLMAQAVDRDTNRPLEPPSEFIVKVQ--DINDNPPEFLHETYHANVP 169
Query: 119 ETXXXXXXXXXXXXSDRDQP--GPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFE 176
E SD D P G + L Y++L G Y E + I +D E
Sbjct: 170 ERSNVGTSVIQVTASDADDPTYGNSAKLVYSILEG--QPYFSVEAQTGIIRTALPNMDRE 227
Query: 177 TVNNFTIKLRVQDQGS--PPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFL 234
+ + ++ +D G L T + +T+ D +D PKF Y + + A G
Sbjct: 228 AKEEYHVVIQAKDMGGHMGGLSGTTKVTITLTDVNDNPPKFPQSVYQISVSEAAVPG--- 284
Query: 235 TTSPGPISAADQDLGINAPLQYSST-GDHKQLIVVNKD----TGQVAATKQLIAELDPSV 289
G + A D D+G N + Y+ GD + + D G + K + E +
Sbjct: 285 -EEVGRVKAKDPDIGENGLVTYNIVDGDGMESFEITTDYETQEGVIKLKKPVDFETKRAY 343
Query: 290 TIVLKATQVD-NPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLL 348
++ ++A V +P + F Y V E A+ G+V+
Sbjct: 344 SLKVEAANVHIDPKFISNGPFKDTVTVKIAVEDADEPPMFLAPSYIHEVQENAAAGTVVG 403
Query: 349 TLTTVPQNTEFRESPLQFYVSDRSFLDK-FAIN-NAGEVILRRSLDYETTSNYFYQVMVT 406
+ ++ + SP+++ + + LD+ F IN G + + LD E T+ V
Sbjct: 404 RVHA--KDPDAANSPIRYSIDRHTDLDRFFTINPEDGFIKTTKPLDREETAWLNITVFAA 461
Query: 407 DSISNDTAS---INISVEDVNEWEPRFRHPQYE 436
+ + + + I V DVN+ P+F P YE
Sbjct: 462 EIHNRHQEAKVPVAIRVLDVNDNAPKFAAP-YE 493
Score = 37.5 bits (83), Expect = 0.21
Identities = 30/126 (23%), Positives = 53/126 (42%), Gaps = 9/126 (7%)
Query: 92 IPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXX----XXXXXSDRDQP--GPH--SA 143
+PV++RV DVNDNAP++ APY + E+ D+D GP +
Sbjct: 472 VPVAIRVLDVNDNAPKF-AAPYEGFICESDQTKPLSNQPIVTISADDKDDTANGPRFIFS 530
Query: 144 LHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQV 203
L ++ P+ + + + + + + + + + D G PP+ S TL +
Sbjct: 531 LPPEIIHNPNFTVRDNRDNTAGVYARRGGFSRQKQDLYLLPIVISDGGIPPMSSTNTLTI 590
Query: 204 TVLDAD 209
V D
Sbjct: 591 KVCGCD 596
>D21254-1|BAA04798.1| 796|Homo sapiens OB-cadherin-1 protein.
Length = 796
Score = 84.6 bits (200), Expect = 1e-15
Identities = 108/453 (23%), Positives = 179/453 (39%), Gaps = 32/453 (7%)
Query: 3 GGAVESFFISEDT--PIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSK--NLT 58
G FF+ E+ P ++G L + D + G+I L +GA V K N+
Sbjct: 54 GWVWNQFFVIEEYTGPDPVLVGRLHSDIDSGD--GNIKYILSGEGAGTIFVIDDKSGNIH 111
Query: 59 LLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVS 118
+ LDREE+ + + V D R +P V V+ D+NDN P++ Y V
Sbjct: 112 ATKTLDREERAQYTLMAQAVDRDTNRPLEPPSEFIVKVQ--DINDNPPEFLHETYHANVP 169
Query: 119 ETXXXXXXXXXXXXSDRDQP--GPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFE 176
E SD D P G + L Y++L G Y E + I +D E
Sbjct: 170 ERSNVGTSVIQVTASDADDPTYGNSAKLVYSILEG--QPYFSVEAQTGIIRTALPNMDRE 227
Query: 177 TVNNFTIKLRVQDQGS--PPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFL 234
+ + ++ +D G L T + +T+ D +D PKF Y + + A G
Sbjct: 228 AKEEYHVVIQAKDMGGHMGGLSGTTKVTITLTDVNDNPPKFPQSVYQISVSEAAVPG--- 284
Query: 235 TTSPGPISAADQDLGINAPLQYSST-GDHKQLIVVNKD----TGQVAATKQLIAELDPSV 289
G + A D D+G N + Y+ GD + + D G + K + E +
Sbjct: 285 -EEVGRVKAKDPDIGENGLVTYNIVDGDGMESFEITTDYETQEGVIKLKKPVDFETKRAY 343
Query: 290 TIVLKATQVD-NPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLL 348
++ ++A V +P + F Y V E A+ G+V+
Sbjct: 344 SLKVEAANVHIDPKFISNGPFKDTVTVKIAVEDADEPPMFLAPSYIHEVQENAAAGTVVG 403
Query: 349 TLTTVPQNTEFRESPLQFYVSDRSFLDK-FAIN-NAGEVILRRSLDYETTSNYFYQVMVT 406
+ ++ + SP+++ + + LD+ F IN G + + LD E T+ V
Sbjct: 404 RVHA--KDPDAANSPIRYSIDRHTDLDRFFTINPEDGFIKTTKPLDREETAWLNITVFAA 461
Query: 407 DSISNDTAS---INISVEDVNEWEPRFRHPQYE 436
+ + + + I V DVN+ P+F P YE
Sbjct: 462 EIHNRHQEAKVPVAIRVLDVNDNAPKFAAP-YE 493
Score = 37.5 bits (83), Expect = 0.21
Identities = 30/126 (23%), Positives = 53/126 (42%), Gaps = 9/126 (7%)
Query: 92 IPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXX----XXXXXSDRDQP--GPH--SA 143
+PV++RV DVNDNAP++ APY + E+ D+D GP +
Sbjct: 472 VPVAIRVLDVNDNAPKF-AAPYEGFICESDQTKPLSNQPIVTISADDKDDTANGPRFIFS 530
Query: 144 LHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQV 203
L ++ P+ + + + + + + + + + D G PP+ S TL +
Sbjct: 531 LPPEIIHNPNFTVRDNRDNTAGVYARRGGFSRQKQDLYLLPIVISDGGIPPMSSTNTLTI 590
Query: 204 TVLDAD 209
V D
Sbjct: 591 KVCGCD 596
>AK000054-1|BAA90911.1| 959|Homo sapiens protein ( Homo sapiens
cDNA FLJ20047 fis, clone COL00577. ).
Length = 959
Score = 84.6 bits (200), Expect = 1e-15
Identities = 100/451 (22%), Positives = 182/451 (40%), Gaps = 43/451 (9%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSKNLTLLRALDREEKIG 70
+ E P+G + TLS S + +I+ R+ I P + + + + + I
Sbjct: 44 VPESIPVGYSVLTLSATDLESNE--NISYRILSSSKEFSIDPKNGTIFTISPVLLLDTIS 101
Query: 71 PSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXX 130
+ V DP + V + + D+N+ AP++ Y + +SE
Sbjct: 102 TTRFLVEA--SDGGNPDPRALTLVEIGIEDMNNYAPEFTVKSYNLSLSEDALVGSTLVTF 159
Query: 131 XXSDRDQPGPHSALHYAVLPGP-----HSEYLGFENELE----PIIVVKKPLDFETVNNF 181
D D ++ + Y+++ G H E F +E +V+ LD E +
Sbjct: 160 SNIDHDWTRENTYVEYSIISGNSQNNFHVETKFFHSEYPYKQVGYLVLLHSLDREASASH 219
Query: 182 TIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPI 241
+ + D G PPL S + + VLD +D P F+ Y + + G+ +T +
Sbjct: 220 ELVILASDSGCPPLSSTAVISIQVLDVNDNPPNFSSLSYHTHVKESTPLGSHITV----V 275
Query: 242 SAADQDLGINAPLQYS-STGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDN 300
SA D+D G +A + Y+ +G+ K + ++TG + K L E T+ ++A+ +
Sbjct: 276 SANDRDTGSHAEIIYNIISGNEKGHFYLEENTGVLYLIKPLDYEKMTKFTLTVQASDAEK 335
Query: 301 PDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFR 360
++ A + QF +S V E S + ++ + +F
Sbjct: 336 -KHFSFAVVFVSVLDDNDHAP-----QFMFSSFSCIVPENLPISSTICSINAL----DFD 385
Query: 361 ESP---LQFYVSDRSFL--------DKFAINN-AGEVILRRSLDYETTSNYFYQVMVTDS 408
P L + + FL D F I+ G++ ++ LDYE + Y V D
Sbjct: 386 AGPYGELTYSIVSPCFLTHGMSYDHDLFLIDPLTGDIHAKQILDYENGNKYCLTVQAKDK 445
Query: 409 ISNDTAS--INISVEDVNEWEPRFRHPQYEF 437
+ TAS + + +E ++E+EP F QY F
Sbjct: 446 -GDATASLVVWVDIEGIDEFEPIFTQDQYFF 475
Score = 69.3 bits (162), Expect = 6e-11
Identities = 65/254 (25%), Positives = 112/254 (44%), Gaps = 25/254 (9%)
Query: 196 YSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQ 255
Y++ L V VLD +D P F+ + Y +P+ G + T +SA DL N +
Sbjct: 16 YTEGALVVRVLDVNDNPPVFSQDFYQVTVPESIPVGYSVLT----LSAT--DLESNENIS 69
Query: 256 YSSTGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXX 315
Y K+ + K+ + L+ + + +++A+ NPD AL +
Sbjct: 70 YRILSSSKEFSIDPKNGTIFTISPVLLLDTISTTRFLVEASDGGNPDPRALTLVEIGIED 129
Query: 316 XXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVP-----QNT--EFR----ESPL 364
+FT K Y+ ++SE A GS L+T + + +NT E+ S
Sbjct: 130 MNNYAP-----EFTVKSYNLSLSEDALVGSTLVTFSNIDHDWTRENTYVEYSIISGNSQN 184
Query: 365 QFYVSDRSFLDKFAINNAGEVILRRSLDYETTSNYFYQVMVTDS---ISNDTASINISVE 421
F+V + F ++ G ++L SLD E ++++ ++ +DS + TA I+I V
Sbjct: 185 NFHVETKFFHSEYPYKQVGYLVLLHSLDREASASHELVILASDSGCPPLSSTAVISIQVL 244
Query: 422 DVNEWEPRFRHPQY 435
DVN+ P F Y
Sbjct: 245 DVNDNPPNFSSLSY 258
Score = 67.7 bits (158), Expect = 2e-10
Identities = 69/281 (24%), Positives = 125/281 (44%), Gaps = 23/281 (8%)
Query: 11 ISEDTPIGSIIGTLSVNGDPSEDLGDITLRL---QEKGAAVGIVPGSKNLTLLRALDREE 67
+ E TP+GS I +S N + +I + EKG + + L L++ LD E+
Sbjct: 262 VKESTPLGSHITVVSANDRDTGSHAEIIYNIISGNEKGHFY-LEENTGVLYLIKPLDYEK 320
Query: 68 KIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXX 127
+ + V+ SF + V V V D ND+APQ+ + ++ V E
Sbjct: 321 M---TKFTLTVQASDAEKKHFSFAV-VFVSVLDDNDHAPQFMFSSFSCIVPENLPISSTI 376
Query: 128 XXXXXSDRDQPGPHSALHYAVL-PGPHSEYLGFENEL---EPI---IVVKKPLDFETVNN 180
D D GP+ L Y+++ P + + ++++L +P+ I K+ LD+E N
Sbjct: 377 CSINALDFDA-GPYGELTYSIVSPCFLTHGMSYDHDLFLIDPLTGDIHAKQILDYENGNK 435
Query: 181 FTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFLTTSPGP 240
+ + ++ +D+G + + V + D+ P FT + Y LP+ ++ + G
Sbjct: 436 YCLTVQAKDKGDAT--ASLVVWVDIEGIDEFEPIFTQDQYFFTLPEKNKDRQLI----GR 489
Query: 241 ISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQL 281
+ A+D D GI+ + Y S G VN+ G + + L
Sbjct: 490 VEASDADAGIDGVILY-SLGTSSPFFSVNRTNGNIYLIRAL 529
Score = 59.3 bits (137), Expect = 6e-08
Identities = 77/349 (22%), Positives = 134/349 (38%), Gaps = 28/349 (8%)
Query: 96 VRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPHSE 155
VRV DVNDN P + Y V V E+ +D + + + Y +L S+
Sbjct: 23 VRVLDVNDNPPVFSQDFYQVTVPESIPVGYSVLTLSATDLES---NENISYRILSS--SK 77
Query: 156 YLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNPKF 215
+ + I + L +T++ + D G+P + T +++ + D ++ P+F
Sbjct: 78 EFSIDPKNGTIFTISPVLLLDTISTTRFLVEASDGGNPDPRALTLVEIGIEDMNNYAPEF 137
Query: 216 TYEHYTALLPDDAEEGTFLTTSPGPISAADQD-LGINAPLQYS-STGDHKQLIVVN---- 269
T + Y L +DA G+ L T S D D N ++YS +G+ + V
Sbjct: 138 TVKSYNLSLSEDALVGSTLVT----FSNIDHDWTRENTYVEYSIISGNSQNNFHVETKFF 193
Query: 270 ------KDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXX 323
K G + L E S +V+ A+ P + A +
Sbjct: 194 HSEYPYKQVGYLVLLHSLDREASASHELVILASDSGCPPLSSTAVISIQVLDVNDNPP-- 251
Query: 324 XXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAINNAG 383
F+ Y T V E GS + ++ ++T + +S + N G
Sbjct: 252 ---NFSSLSYHTHVKESTPLGSHITVVSANDRDTGSHAEIIYNIISGNEKGHFYLEENTG 308
Query: 384 EVILRRSLDYETTSNYFYQVMVTDSISN--DTASINISVEDVNEWEPRF 430
+ L + LDYE + + V +D+ A + +SV D N+ P+F
Sbjct: 309 VLYLIKPLDYEKMTKFTLTVQASDAEKKHFSFAVVFVSVLDDNDHAPQF 357
>AB209760-1|BAD92997.1| 798|Homo sapiens cadherin 11, type 2
isoform 1 preproprotein variant protein.
Length = 798
Score = 84.6 bits (200), Expect = 1e-15
Identities = 108/453 (23%), Positives = 179/453 (39%), Gaps = 32/453 (7%)
Query: 3 GGAVESFFISEDT--PIGSIIGTLSVNGDPSEDLGDITLRLQEKGAAVGIVPGSK--NLT 58
G FF+ E+ P ++G L + D + G+I L +GA V K N+
Sbjct: 56 GWVWNQFFVIEEYTGPDPVLVGRLHSDIDSGD--GNIKYILSGEGAGTIFVIDDKSGNIH 113
Query: 59 LLRALDREEKIGPSNVYVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVS 118
+ LDREE+ + + V D R +P V V+ D+NDN P++ Y V
Sbjct: 114 ATKTLDREERAQYTLMAQAVDRDTNRPLEPPSEFIVKVQ--DINDNPPEFLHETYHANVP 171
Query: 119 ETXXXXXXXXXXXXSDRDQP--GPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFE 176
E SD D P G + L Y++L G Y E + I +D E
Sbjct: 172 ERSNVGTSVIQVTASDADDPTYGNSAKLVYSILEG--QPYFSVEAQTGIIRTALPNMDRE 229
Query: 177 TVNNFTIKLRVQDQGS--PPLYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGTFL 234
+ + ++ +D G L T + +T+ D +D PKF Y + + A G
Sbjct: 230 AKEEYHVVIQAKDMGGHMGGLSGTTKVTITLTDVNDNPPKFPQSVYQMSVSEAAVPG--- 286
Query: 235 TTSPGPISAADQDLGINAPLQYSST-GDHKQLIVVNKD----TGQVAATKQLIAELDPSV 289
G + A D D+G N + Y+ GD + + D G + K + E +
Sbjct: 287 -EEVGRVKAKDPDIGENGLVTYNIVDGDGMESFEITTDYETQEGVIKLKKPVDFETKRAY 345
Query: 290 TIVLKATQVD-NPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLL 348
++ ++A V +P + F Y V E A+ G+V+
Sbjct: 346 SLKVEAANVHIDPKFISNGPFKDTVTVKIAVEDADEPPMFLAPSYIHEVQENAAAGTVVG 405
Query: 349 TLTTVPQNTEFRESPLQFYVSDRSFLDK-FAIN-NAGEVILRRSLDYETTSNYFYQVMVT 406
+ ++ + SP+++ + + LD+ F IN G + + LD E T+ V
Sbjct: 406 RVHA--KDPDAANSPIRYSIDRHTDLDRFFTINPEDGFIKTTKPLDREETAWLNITVFAA 463
Query: 407 DSISNDTAS---INISVEDVNEWEPRFRHPQYE 436
+ + + + I V DVN+ P+F P YE
Sbjct: 464 EIHNRHQEAKVPVAIRVLDVNDNAPKFAAP-YE 495
Score = 37.5 bits (83), Expect = 0.21
Identities = 30/126 (23%), Positives = 53/126 (42%), Gaps = 9/126 (7%)
Query: 92 IPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXX----XXXXXSDRDQP--GPH--SA 143
+PV++RV DVNDNAP++ APY + E+ D+D GP +
Sbjct: 474 VPVAIRVLDVNDNAPKF-AAPYEGFICESDQTKPLSNQPIVTISADDKDDTANGPRFIFS 532
Query: 144 LHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQV 203
L ++ P+ + + + + + + + + + D G PP+ S TL +
Sbjct: 533 LPPEIIHNPNFTVRDNRDNTAGVYARRGGFSRQKQDLYLLPIVISDGGIPPMSSTNTLTI 592
Query: 204 TVLDAD 209
V D
Sbjct: 593 KVCGCD 598
>AB160984-1|BAD08246.1| 1123|Homo sapiens KIAA0811 protein protein.
Length = 1123
Score = 84.6 bits (200), Expect = 1e-15
Identities = 44/158 (27%), Positives = 83/158 (52%), Gaps = 2/158 (1%)
Query: 75 YVNVRCDRRRTTDPSFVIPVSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSD 134
++++ C R+ ++ S V V V + DVN++ PQ+ PY+ RV E +D
Sbjct: 148 FLSIECSRKSSSSLSDVTTVMVNITDVNEHRPQFPQDPYSTRVLENALVGDVILTVSATD 207
Query: 135 RDQPGPHSALHYAVLPGPHSEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPP 194
D P +S + Y+++ G + + + + V K LD E +++++KLR D G PP
Sbjct: 208 EDGP-LNSDITYSLIGGNQLGHFTIHPK-KGELQVAKALDREQASSYSLKLRATDSGQPP 265
Query: 195 LYSDTTLQVTVLDADDQNPKFTYEHYTALLPDDAEEGT 232
L+ DT + + V D +D P+F +Y+ + +++ G+
Sbjct: 266 LHEDTDIAIQVADVNDNPPRFFQLNYSTTVQENSPIGS 303
Score = 73.3 bits (172), Expect = 3e-12
Identities = 74/339 (21%), Positives = 134/339 (39%), Gaps = 17/339 (5%)
Query: 94 VSVRVWDVNDNAPQWEGAPYAVRVSETXXXXXXXXXXXXSDRDQPGPHSALHYAVLPGPH 153
V+V V + D P + ++V+V E R PG Y V+ G
Sbjct: 64 VTVSVVGLEDYLPVFLNTEHSVQVPEDAPPGTEVLQLATLTR--PGAEKT-GYRVVSGNE 120
Query: 154 SEYLGFENELEPIIVVKKPLDFETVNNFTIKLRVQDQGSPPLYSDTTLQVTVLDADDQNP 213
+ I+ V LDFET + + + + S L TT+ V + D ++ P
Sbjct: 121 QGRFRLDARTG-ILYVNASLDFETSPKYFLSIECSRKSSSSLSDVTTVMVNITDVNEHRP 179
Query: 214 KFTYEHYTALLPDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHK-QLIVVNKDT 272
+F + Y+ + ++A G + T +SA D+D +N+ + YS G ++ ++
Sbjct: 180 QFPQDPYSTRVLENALVGDVILT----VSATDEDGPLNSDITYSLIGGNQLGHFTIHPKK 235
Query: 273 GQVAATKQLIAELDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQ 332
G++ K L E S ++ L+AT P + + +F Q
Sbjct: 236 GELQVAKALDREQASSYSLKLRATDSGQPPLHEDTDIAIQVADVNDNPP-----RFFQLN 290
Query: 333 YSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAINNAGEVILRRSLD 392
YSTTV E + GS +L L ++ P F ++ + F + G ++ L
Sbjct: 291 YSTTVQENSPIGSKVLQLILSDPDSPENGPPYSFRITKGNNGSAFRVTPDGWLVTAEGLS 350
Query: 393 YETTSNYFYQVMVTDS---ISNDTASINISVEDVNEWEP 428
Y Q+ +DS + S+++ V + + + P
Sbjct: 351 RRAQEWYQLQIQASDSGIPPLSSLTSVHVHVTEQSHYAP 389
Score = 71.3 bits (167), Expect = 1e-11
Identities = 82/357 (22%), Positives = 140/357 (39%), Gaps = 20/357 (5%)
Query: 166 IIVVKKPLDFETVNNFTIKLRVQDQGSP-PLYSDTTLQVTVLDADDQNPKFTYEHYTALL 224
+I ++KPL + +R D G+P PL + T+ V+V+ +D P F ++ +
Sbjct: 28 VIRLEKPLQVRPQAPLELTVRASDLGTPIPLSTLGTVTVSVVGLEDYLPVFLNTEHSVQV 87
Query: 225 PDDAEEGTFLTTSPGPISAADQDLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLIAE 284
P+DA GT + + G +G+ + ++ TG + L E
Sbjct: 88 PEDAPPGTEVLQLATLTRPGAEKTGYRVV-----SGNEQGRFRLDARTGILYVNASLDFE 142
Query: 285 LDPSVTIVLKATQVDNPDRYALATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPG 344
P + ++ ++ + + T+ QF Q YST V E A G
Sbjct: 143 TSPKYFLSIECSRKSSSSLSDVTTVMVNITDVNEHRP-----QFPQDPYSTRVLENALVG 197
Query: 345 SVLLTLTTVPQNTEFRESPLQFYVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQV 403
V+LT++ ++ S + + + + L F I+ GE+ + ++LD E S+Y ++
Sbjct: 198 DVILTVSATDEDGPLN-SDITYSLIGGNQLGHFTIHPKKGELQVAKALDREQASSYSLKL 256
Query: 404 MVTDS----ISNDTASINISVEDVNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXV 459
TDS + DT I I V DVN+ PRF Y
Sbjct: 257 RATDSGQPPLHEDT-DIAIQVADVNDNPPRFFQLNYSTTVQENSPIGSKVLQLILSDPDS 315
Query: 460 AHDGDAGTLALSLAGQHARMFYINASGDLFLREEAIGNLNSSSLHLVATAIDSGIPP 516
+G + ++ G + F + G L + E + L A DSGIPP
Sbjct: 316 PENGPPYSFRIT-KGNNGSAFRVTPDGWL-VTAEGLSRRAQEWYQLQIQASDSGIPP 370
Score = 54.0 bits (124), Expect = 2e-06
Identities = 61/274 (22%), Positives = 103/274 (37%), Gaps = 13/274 (4%)
Query: 247 DLGINAPLQYSSTGDHKQLIVVNKDTGQVAATKQLIAELDPSVTIVLKATQVDNPDRYAL 306
D G NA + YS + ++ TG + K L + + ++A+ + P L
Sbjct: 1 DQGANAQVVYSLPDSAEGHFSIDATTGVIRLEKPLQVRPQAPLELTVRASDLGTP--IPL 58
Query: 307 ATLXXXXXXXXXXXXXXXXLQFTQKQYSTTVSEGASPGSVLLTLTTVPQNTEFRESPLQF 366
+TL F ++S V E A PG+ +L L T+ T +
Sbjct: 59 STLGTVTVSVVGLEDYLPV--FLNTEHSVQVPEDAPPGTEVLQLATL---TRPGAEKTGY 113
Query: 367 YVSDRSFLDKFAIN-NAGEVILRRSLDYETTSNYFYQVMVTDSISN---DTASINISVED 422
V + +F ++ G + + SLD+ET+ YF + + S+ D ++ +++ D
Sbjct: 114 RVVSGNEQGRFRLDARTGILYVNASLDFETSPKYFLSIECSRKSSSSLSDVTTVMVNITD 173
Query: 423 VNEWEPRFRHPQYEFEXXXXXXXXXXXXXXXXXXXXVAHDGDAGTLALSLAGQHARMFYI 482
VNE P+F Y + D T +L + G F I
Sbjct: 174 VNEHRPQFPQDPYSTRVLENALVGDVILTVSATDEDGPLNSDI-TYSL-IGGNQLGHFTI 231
Query: 483 NASGDLFLREEAIGNLNSSSLHLVATAIDSGIPP 516
+ +A+ +SS L A DSG PP
Sbjct: 232 HPKKGELQVAKALDREQASSYSLKLRATDSGQPP 265
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.315 0.133 0.392
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 117,433,413
Number of Sequences: 224733
Number of extensions: 4672663
Number of successful extensions: 13276
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 455
Number of HSP's successfully gapped in prelim test: 95
Number of HSP's that attempted gapping in prelim test: 5917
Number of HSP's gapped (non-prelim): 3554
length of query: 900
length of database: 73,234,838
effective HSP length: 97
effective length of query: 803
effective length of database: 51,435,737
effective search space: 41302896811
effective search space used: 41302896811
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 42 (22.0 bits)
S2: 70 (32.3 bits)
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