Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA002144-TA|BGIBMGA002144-PA|IPR013594|Dynein heavy chain,
N-terminal region 1
(1013 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AY045575-1|AAK92217.1| 4624|Homo sapiens axonemal dynein heavy c... 325 4e-88
AL391415-3|CAI21588.1| 4695|Homo sapiens dynein, axonemal, heavy... 252 4e-66
AL391415-2|CAI21587.1| 4176|Homo sapiens dynein, axonemal, heavy... 252 4e-66
AL353700-3|CAI20294.1| 4695|Homo sapiens dynein, axonemal, heavy... 252 4e-66
AL353700-2|CAI20293.1| 4176|Homo sapiens dynein, axonemal, heavy... 252 4e-66
AL035690-5|CAI19770.1| 4695|Homo sapiens dynein, axonemal, heavy... 252 4e-66
AL035555-4|CAI19822.1| 4695|Homo sapiens dynein, axonemal, heavy... 252 4e-66
AL035555-3|CAI19821.1| 4176|Homo sapiens dynein, axonemal, heavy... 252 4e-66
AL034345-4|CAI42436.1| 4695|Homo sapiens dynein, axonemal, heavy... 252 4e-66
AL034345-3|CAI42435.1| 4176|Homo sapiens dynein, axonemal, heavy... 252 4e-66
AL353700-1|CAI20292.1| 4490|Homo sapiens dynein, axonemal, heavy... 246 2e-64
AL035690-1|CAI19769.1| 4490|Homo sapiens dynein, axonemal, heavy... 246 2e-64
AL035555-1|CAI19819.1| 4490|Homo sapiens dynein, axonemal, heavy... 246 2e-64
AL034345-1|CAI42433.1| 4490|Homo sapiens dynein, axonemal, heavy... 246 2e-64
AF356519-1|AAK60620.1| 4490|Homo sapiens axonemal dynein heavy c... 246 2e-64
AK125475-1|BAC86173.1| 913|Homo sapiens protein ( Homo sapiens ... 96 6e-19
AJ320497-1|CAC60121.1| 4523|Homo sapiens axonemal beta heavy cha... 82 1e-14
AY050643-1|AAL14192.1| 200|Homo sapiens dynein heavy chain prot... 81 3e-14
BC034225-1|AAH34225.1| 872|Homo sapiens DNAH2 protein protein. 80 3e-14
AC102952-1|AAS07505.1| 453|Homo sapiens Homo sapiens dynein, ax... 77 2e-13
AJ404468-1|CAB94756.1| 4486|Homo sapiens axonemal dynein heavy c... 60 4e-08
AF257737-1|AAF69004.1| 4486|Homo sapiens ciliary dynein heavy ch... 60 4e-08
BC112284-1|AAI12285.1| 566|Homo sapiens dynein, axonemal, heavy... 59 9e-08
BC105107-1|AAI05108.1| 566|Homo sapiens dynein, axonemal, heavy... 59 9e-08
AK097776-1|BAC05170.1| 566|Homo sapiens protein ( Homo sapiens ... 59 9e-08
AB040936-1|BAA96027.2| 4464|Homo sapiens KIAA1503 protein protein. 58 2e-07
Y10601-1|CAA71610.1| 1119|Homo sapiens ankyrin-like protein prot... 38 0.18
BC118914-1|AAI18915.1| 915|Homo sapiens oxysterol binding prote... 33 6.8
BC064370-1|AAH64370.1| 2335|Homo sapiens PRP8 pre-mRNA processin... 33 6.8
AL079299-1|CAI14632.1| 917|Homo sapiens oxysterol binding prote... 33 6.8
AL022336-1|CAI22805.1| 917|Homo sapiens oxysterol binding prote... 33 6.8
AK131374-1|BAD18525.1| 743|Homo sapiens protein ( Homo sapiens ... 33 6.8
AF323731-1|AAG53406.1| 916|Homo sapiens OSBP-related protein 4 ... 33 6.8
AF288742-1|AAK56865.1| 878|Homo sapiens oxysterol binding prote... 33 6.8
AF288741-1|AAK56864.1| 878|Homo sapiens oxysterol binding prote... 33 6.8
AF092565-1|AAC61776.1| 2335|Homo sapiens splicing factor Prp8 pr... 33 6.8
AB051451-1|BAB33334.2| 920|Homo sapiens KIAA1664 protein protein. 33 6.8
AB007510-1|BAA22563.1| 2335|Homo sapiens PRP8 protein protein. 33 6.8
>AY045575-1|AAK92217.1| 4624|Homo sapiens axonemal dynein heavy
chain DNAH5 protein.
Length = 4624
Score = 325 bits (799), Expect = 4e-88
Identities = 183/574 (31%), Positives = 312/574 (54%), Gaps = 32/574 (5%)
Query: 39 MDPRLEFTFQLLIDGTGLPRHAIMDHVFEGNMLDDINQLFLPHMRNKLLWYYQDVEEIEQ 98
+D R + F ++ L + + D + EGN ++ I+QLF L++YYQDVEE E
Sbjct: 33 LDARHNYLFAIVASCLDLNKTEVEDAILEGNQIERIDQLFAVGGLRHLMFYYQDVEEAET 92
Query: 99 RPVPE-NTKSRQQGKQPPPQVTWKRKLFLSDGWDVKFTGVCIYMFRINVSKQLPEEGFHK 157
+ + GK P K+F+++G DV TGVC++ R + SK + + H+
Sbjct: 93 GQLGSLGGVNLVSGKIKKP------KVFVTEGNDVALTGVCVFFIRTDPSKAITPDNIHQ 146
Query: 158 DLFCGILNAEKVGMVTAIERVMEHVYMSALAHPSSDGDEDETRFPI--VKNQLLPGLRSF 215
++ +L+A G++ ++ R++ +++ AL S E E ++ + L L F
Sbjct: 147 EVSFNMLDAADGGLLNSVRRLLSDIFIPALRATSHGWGELEGLQDAANIRQEFLSSLEGF 206
Query: 216 CSALKVC-EDVCNQVNLFEDGLALMAPIQDHTQLKDMAKNPNTITMLEERVTEWIKKVME 274
+ L E + +VNL + + + +++ T +A NP T+ +E+ + WIK+
Sbjct: 207 VNVLSGAQESLKEKVNLRKCDILELKTLKEPTDYLTLANNPETLGKIEDCMKVWIKQT-- 264
Query: 275 VASLLIFPNHAFNDQILSESEQLRREVDSSGPQDELEYWKKRGAQFSQLVSYLQENEVQL 334
+Q+L+E+ QL +E D GP+ ELE+WKKR ++F+ L+ L+ +V+
Sbjct: 265 -------------EQVLAENNQLLKEADDVGPRAELEHWKKRLSKFNYLLEQLKSPDVKA 311
Query: 335 TLSCLQLANSKVIKQWRDTDHKITFCYNEAKDNAKFVQAMEKCCHSLYLDDPVKIKDSIL 394
L+ L A SK++K WR+ D +IT NEAKDN K++ +EKCC LY DP+ + D+I
Sbjct: 312 VLAVLAAAKSKLLKTWREMDIRITDATNEAKDNVKYLYTLEKCCDPLYSSDPLSMMDAIP 371
Query: 395 SLLQTVRLIHSVSQFYNTSERISSLMVKITNQMIETCKQYITCRFKDTIWSQERSLVRDK 454
+L+ +++I+S+S +YNTSE+I+SL VK+TNQ+I CK YIT +IW+Q + +V +K
Sbjct: 372 TLINAIKMIYSISHYYNTSEKITSLFVKVTNQIISACKAYITNNGTASIWNQPQDVVEEK 431
Query: 455 LIHCINLNRTYRETYIFVKNH-PFLPNTEQFSFSENYVFGKFDTFCKRLNKIIAMFDLTD 513
++ I L + Y+ + K PN +QF FSE Y+FGKF+TF +RL KII +F
Sbjct: 432 ILSAIKLKQEYQLCFHKTKQKLKQNPNAKQFDFSEMYIFGKFETFHRRLAKIIDIFTTLK 491
Query: 514 DYNYLFEKRMXXXXXXXXXXXAVHTFEEAKKAVTTCQYDYLDYRNNEFDKDYHAFEDKIN 573
Y+ L + + + + K +Y++LD R +FD+DY F + N
Sbjct: 492 TYSVLQDSTIEGLEDMATKYQGIVATIKKK------EYNFLDQRKMDFDQDYEEFCKQTN 545
Query: 574 ALKESIGCTIEENFSSVWETPQGIKFLTRFEKVS 607
L + ++ F+ + T Q ++ L +FE+++
Sbjct: 546 DLHNELRKFMDVTFAKIQNTNQALRMLKKFERLN 579
Score = 116 bits (279), Expect = 4e-25
Identities = 85/376 (22%), Positives = 169/376 (44%), Gaps = 18/376 (4%)
Query: 617 RIKWSRCLMQNMIEIVESVCAHPVLRGLPASADMMRKYTNTRTLMNNYEDMMKAVWMNQN 676
+I W+R L + + ++ HP + + ++R Y ++ +E + W+ Q
Sbjct: 626 KILWARQLFHRIQQPMQLFQQHPAVLSTAEAKPIIRSYNRMAKVLLEFEVLFHRAWLRQ- 684
Query: 677 LWDVDESLNNSLL-KIDETGCVAVNLDKNIKLLIRESDCLVKMGVPLPIVCHSLYAKKYY 735
+ ++ L SLL K TG + VN D I +L RE++C+ +MG+ + + SL+ K+
Sbjct: 685 IEEIHVGLEASLLVKAPGTGELFVNFDPQILILFRETECMAQMGLEVSPLATSLFQKRDR 744
Query: 736 FTLVNDSLQFLLEDYLRTVRRVKLEVRPLFLPQXXXXXXXXXXXXXXXCWTSEGWKEFID 795
+ +++ +L +Y R ++ + L +P WTS + +++
Sbjct: 745 YKRNFSNMKMMLAEYQRVKSKIPAAIEQLIVPHLAKVDEALQPGLAALTWTSLNIEAYLE 804
Query: 796 RANAAIKSFDVLVTRVHDIYTNRIIYMLSGMQEVTLITLPEETPWSVQEFVEKVESGCRN 855
A IK ++L+ RV+D+ RI +L M L LP+E P + +EF++ + C N
Sbjct: 805 NTFAKIKDLELLLDRVNDLIEFRIDAILEEMSSTPLCQLPQEEPLTCEEFLQMTKDLCVN 864
Query: 856 ACVELNRKSXXXXXXXXXXXXXXKKAAQQIRPTEINPDFEFLIAEDDPQSS--GAASSTN 913
L+ KS ++A ++ + D E L E+ + S + + N
Sbjct: 865 GAQILHFKS-----------SLVEEAVNEL--VNMLLDVEVLSEEESEKISNENSVNYKN 911
Query: 914 ESTSSGQQ-DWSAVWECFESPHRLLSTPAGGLSKSMQEMVKNAVNEMRRYYSRKVVDVLI 972
ES++ ++ ++ + + L K EM+ E+ +++ + +D L+
Sbjct: 912 ESSAKREEGNFDTLTSSINARANALLLTTVTRKKKETEMLGEEARELLSHFNHQNMDALL 971
Query: 973 RVKRRTLDVIIKQFSS 988
+V R TL+ I K+ S
Sbjct: 972 KVTRNTLEAIRKRIHS 987
>AL391415-3|CAI21588.1| 4695|Homo sapiens dynein, axonemal, heavy
chain 8 protein.
Length = 4695
Score = 252 bits (618), Expect = 4e-66
Identities = 165/583 (28%), Positives = 283/583 (48%), Gaps = 55/583 (9%)
Query: 39 MDPRLEFTFQLLIDGTGLPRHAIMDHVFEGNMLDDINQLFLPHMRNKLLWYYQ--DVEEI 96
+DP ++ F++L + GL + + + + L+ F L + YQ DV I
Sbjct: 132 IDPSYKYIFEILAENLGLDIVTVEELILDCPSLEAFTNFFAKDGCKTLKFLYQEGDVPGI 191
Query: 97 E-QRPVPENTKSRQQGKQPPPQVTWKRKLFLSDGWDVKFTGVCIYMFRINVSKQLPEEGF 155
E R + TK + KL++ + K G+CI+ R + +
Sbjct: 192 ECGRTIAGATKGAKM-----------MKLYIDNAAPDKLKGLCIFFVRCRNDVAINVKTI 240
Query: 156 HKDLFCGILNAEKVGMVTAIERVMEHVYMSALA--------HPSSDGDEDETRFPIVKNQ 207
++ +L+A K G++ I ++ ++++ A+ + S G+ ++ F N+
Sbjct: 241 QEEALFTVLDASK-GLLNGIRDMLANIFLPAVLATNNWGALNQSKQGESEKHIFTETINR 299
Query: 208 LLPGLRSFCSALKVCEDVCNQVNLFEDGLALMAPIQDHTQLKDMAKNPNTITMLEERVTE 267
L SF ++ + ++ ++ + + ++ A N T+ LEE +
Sbjct: 300 YL----SFLDGARISIEGTVKLKTIDN--VNFSKLHTFEEVTAAASNSETVHQLEEVLMV 353
Query: 268 WIKKVMEVASLLIFPNHAFNDQILSESEQLRREVDSSGPQDELEYWKKRGAQFSQLVSYL 327
W K++ +Q+L ESEQ+R+E SGP ELE+WK+ A+F+ ++ +
Sbjct: 354 WYKQI---------------EQVLIESEQMRKEAGDSGPLTELEHWKRMSAKFNYIIEQI 398
Query: 328 QENEVQLTLSCLQLANSKVIKQWRDTDHKITFCYNEAKDNAKFVQAMEKCCHSLYLDDPV 387
+ + ++ L +A+SK++K WRD D +IT NE+KDN +++ +EK C LY D V
Sbjct: 399 KGPSCKAVINVLNVAHSKLLKNWRDLDARITDTANESKDNVRYLYTLEKVCQPLYNHDLV 458
Query: 388 KIKDSILSLLQTVRLIHSVSQFYNTSERISSLMVKITNQMIETCKQYITCRFKDTIWSQE 447
+ I +L+ +R+IH VS++YNTSER++SL +K+TNQM+ CK YIT + +W QE
Sbjct: 459 SMAHGIQNLINAIRMIHGVSRYYNTSERMTSLFIKVTNQMVTACKAYITDGGLNHVWDQE 518
Query: 448 RSLVRDKLIHCINLNRTYRETYIFVKNHPFLPNT---EQFSFSENYVFGKFDTFCKRLNK 504
+V K+ CI L + Y+ + F K + + + F SE Y+FGKF+ FCKRL K
Sbjct: 519 TPVVLKKIQDCIFLFKEYQAS--FHKTRKLISESSGEKSFEVSEMYIFGKFEAFCKRLEK 576
Query: 505 IIAMFDLTDDYNYLFEKRMXXXXXXXXXXXAVHTFEEAKKAVTTCQYDYLDYRNNEFDKD 564
I M + Y+ L + F + V QYD LD R EFD D
Sbjct: 577 ITEMITVVQTYSTLSNSTIEGIDIMAI------KFRNIYQGVKKKQYDILDPRRTEFDTD 630
Query: 565 YHAFEDKINALKESIGCTIEENFSSVWETPQGIKFLTRFEKVS 607
+ F KIN L+ I + +F + + Q ++ L RF+K++
Sbjct: 631 FLDFMTKINGLEVQIQAFMNSSFGKILSSQQALQLLQRFQKLN 673
Score = 64.9 bits (151), Expect = 1e-09
Identities = 53/249 (21%), Positives = 103/249 (41%), Gaps = 2/249 (0%)
Query: 617 RIKWSRCLMQNMIEIVESVCAHPVLRGLPASADMMRKYTNTRTLMNNYEDMMKAVWMNQN 676
+I W R L + + E + + + P ++R+Y ++ +E + W+ +
Sbjct: 722 KILWVRQLYRRISEPINYFFKNSDILSSPDGKAVIRQYNKISYVLVEFEVVYHTAWIRE- 780
Query: 677 LWDVDESLNNSL-LKIDETGCVAVNLDKNIKLLIRESDCLVKMGVPLPIVCHSLYAKKYY 735
+ + +L +L ++ ETG + VN D I ++RE+ C++KM + +P L +
Sbjct: 781 ISQLHYALQATLFVRHPETGKLLVNFDPKILEVVRETKCMIKMKLDVPEQAKRLLKLESK 840
Query: 736 FTLVNDSLQFLLEDYLRTVRRVKLEVRPLFLPQXXXXXXXXXXXXXXXCWTSEGWKEFID 795
LQ LL+ Y + V L P+ W+S + F
Sbjct: 841 LKADKLYLQGLLQYYDELCQEVPSVFVNLMTPKMKKVESVLRQGLTVLTWSSLTLESFFQ 900
Query: 796 RANAAIKSFDVLVTRVHDIYTNRIIYMLSGMQEVTLITLPEETPWSVQEFVEKVESGCRN 855
+ F+ L+ ++ D+ I +L + + LI+LPE V++ + E+ +
Sbjct: 901 EVELVLDMFNQLLKKISDLCEMHIDTVLKEIAKTVLISLPESGATKVEDMLTLNETYTKE 960
Query: 856 ACVELNRKS 864
LN KS
Sbjct: 961 WADILNHKS 969
>AL391415-2|CAI21587.1| 4176|Homo sapiens dynein, axonemal, heavy
chain 8 protein.
Length = 4176
Score = 252 bits (618), Expect = 4e-66
Identities = 165/583 (28%), Positives = 283/583 (48%), Gaps = 55/583 (9%)
Query: 39 MDPRLEFTFQLLIDGTGLPRHAIMDHVFEGNMLDDINQLFLPHMRNKLLWYYQ--DVEEI 96
+DP ++ F++L + GL + + + + L+ F L + YQ DV I
Sbjct: 132 IDPSYKYIFEILAENLGLDIVTVEELILDCPSLEAFTNFFAKDGCKTLKFLYQEGDVPGI 191
Query: 97 E-QRPVPENTKSRQQGKQPPPQVTWKRKLFLSDGWDVKFTGVCIYMFRINVSKQLPEEGF 155
E R + TK + KL++ + K G+CI+ R + +
Sbjct: 192 ECGRTIAGATKGAKM-----------MKLYIDNAAPDKLKGLCIFFVRCRNDVAINVKTI 240
Query: 156 HKDLFCGILNAEKVGMVTAIERVMEHVYMSALA--------HPSSDGDEDETRFPIVKNQ 207
++ +L+A K G++ I ++ ++++ A+ + S G+ ++ F N+
Sbjct: 241 QEEALFTVLDASK-GLLNGIRDMLANIFLPAVLATNNWGALNQSKQGESEKHIFTETINR 299
Query: 208 LLPGLRSFCSALKVCEDVCNQVNLFEDGLALMAPIQDHTQLKDMAKNPNTITMLEERVTE 267
L SF ++ + ++ ++ + + ++ A N T+ LEE +
Sbjct: 300 YL----SFLDGARISIEGTVKLKTIDN--VNFSKLHTFEEVTAAASNSETVHQLEEVLMV 353
Query: 268 WIKKVMEVASLLIFPNHAFNDQILSESEQLRREVDSSGPQDELEYWKKRGAQFSQLVSYL 327
W K++ +Q+L ESEQ+R+E SGP ELE+WK+ A+F+ ++ +
Sbjct: 354 WYKQI---------------EQVLIESEQMRKEAGDSGPLTELEHWKRMSAKFNYIIEQI 398
Query: 328 QENEVQLTLSCLQLANSKVIKQWRDTDHKITFCYNEAKDNAKFVQAMEKCCHSLYLDDPV 387
+ + ++ L +A+SK++K WRD D +IT NE+KDN +++ +EK C LY D V
Sbjct: 399 KGPSCKAVINVLNVAHSKLLKNWRDLDARITDTANESKDNVRYLYTLEKVCQPLYNHDLV 458
Query: 388 KIKDSILSLLQTVRLIHSVSQFYNTSERISSLMVKITNQMIETCKQYITCRFKDTIWSQE 447
+ I +L+ +R+IH VS++YNTSER++SL +K+TNQM+ CK YIT + +W QE
Sbjct: 459 SMAHGIQNLINAIRMIHGVSRYYNTSERMTSLFIKVTNQMVTACKAYITDGGLNHVWDQE 518
Query: 448 RSLVRDKLIHCINLNRTYRETYIFVKNHPFLPNT---EQFSFSENYVFGKFDTFCKRLNK 504
+V K+ CI L + Y+ + F K + + + F SE Y+FGKF+ FCKRL K
Sbjct: 519 TPVVLKKIQDCIFLFKEYQAS--FHKTRKLISESSGEKSFEVSEMYIFGKFEAFCKRLEK 576
Query: 505 IIAMFDLTDDYNYLFEKRMXXXXXXXXXXXAVHTFEEAKKAVTTCQYDYLDYRNNEFDKD 564
I M + Y+ L + F + V QYD LD R EFD D
Sbjct: 577 ITEMITVVQTYSTLSNSTIEGIDIMAI------KFRNIYQGVKKKQYDILDPRRTEFDTD 630
Query: 565 YHAFEDKINALKESIGCTIEENFSSVWETPQGIKFLTRFEKVS 607
+ F KIN L+ I + +F + + Q ++ L RF+K++
Sbjct: 631 FLDFMTKINGLEVQIQAFMNSSFGKILSSQQALQLLQRFQKLN 673
Score = 64.9 bits (151), Expect = 1e-09
Identities = 53/249 (21%), Positives = 103/249 (41%), Gaps = 2/249 (0%)
Query: 617 RIKWSRCLMQNMIEIVESVCAHPVLRGLPASADMMRKYTNTRTLMNNYEDMMKAVWMNQN 676
+I W R L + + E + + + P ++R+Y ++ +E + W+ +
Sbjct: 722 KILWVRQLYRRISEPINYFFKNSDILSSPDGKAVIRQYNKISYVLVEFEVVYHTAWIRE- 780
Query: 677 LWDVDESLNNSL-LKIDETGCVAVNLDKNIKLLIRESDCLVKMGVPLPIVCHSLYAKKYY 735
+ + +L +L ++ ETG + VN D I ++RE+ C++KM + +P L +
Sbjct: 781 ISQLHYALQATLFVRHPETGKLLVNFDPKILEVVRETKCMIKMKLDVPEQAKRLLKLESK 840
Query: 736 FTLVNDSLQFLLEDYLRTVRRVKLEVRPLFLPQXXXXXXXXXXXXXXXCWTSEGWKEFID 795
LQ LL+ Y + V L P+ W+S + F
Sbjct: 841 LKADKLYLQGLLQYYDELCQEVPSVFVNLMTPKMKKVESVLRQGLTVLTWSSLTLESFFQ 900
Query: 796 RANAAIKSFDVLVTRVHDIYTNRIIYMLSGMQEVTLITLPEETPWSVQEFVEKVESGCRN 855
+ F+ L+ ++ D+ I +L + + LI+LPE V++ + E+ +
Sbjct: 901 EVELVLDMFNQLLKKISDLCEMHIDTVLKEIAKTVLISLPESGATKVEDMLTLNETYTKE 960
Query: 856 ACVELNRKS 864
LN KS
Sbjct: 961 WADILNHKS 969
>AL353700-3|CAI20294.1| 4695|Homo sapiens dynein, axonemal, heavy
chain 8 protein.
Length = 4695
Score = 252 bits (618), Expect = 4e-66
Identities = 165/583 (28%), Positives = 283/583 (48%), Gaps = 55/583 (9%)
Query: 39 MDPRLEFTFQLLIDGTGLPRHAIMDHVFEGNMLDDINQLFLPHMRNKLLWYYQ--DVEEI 96
+DP ++ F++L + GL + + + + L+ F L + YQ DV I
Sbjct: 132 IDPSYKYIFEILAENLGLDIVTVEELILDCPSLEAFTNFFAKDGCKTLKFLYQEGDVPGI 191
Query: 97 E-QRPVPENTKSRQQGKQPPPQVTWKRKLFLSDGWDVKFTGVCIYMFRINVSKQLPEEGF 155
E R + TK + KL++ + K G+CI+ R + +
Sbjct: 192 ECGRTIAGATKGAKM-----------MKLYIDNAAPDKLKGLCIFFVRCRNDVAINVKTI 240
Query: 156 HKDLFCGILNAEKVGMVTAIERVMEHVYMSALA--------HPSSDGDEDETRFPIVKNQ 207
++ +L+A K G++ I ++ ++++ A+ + S G+ ++ F N+
Sbjct: 241 QEEALFTVLDASK-GLLNGIRDMLANIFLPAVLATNNWGALNQSKQGESEKHIFTETINR 299
Query: 208 LLPGLRSFCSALKVCEDVCNQVNLFEDGLALMAPIQDHTQLKDMAKNPNTITMLEERVTE 267
L SF ++ + ++ ++ + + ++ A N T+ LEE +
Sbjct: 300 YL----SFLDGARISIEGTVKLKTIDN--VNFSKLHTFEEVTAAASNSETVHQLEEVLMV 353
Query: 268 WIKKVMEVASLLIFPNHAFNDQILSESEQLRREVDSSGPQDELEYWKKRGAQFSQLVSYL 327
W K++ +Q+L ESEQ+R+E SGP ELE+WK+ A+F+ ++ +
Sbjct: 354 WYKQI---------------EQVLIESEQMRKEAGDSGPLTELEHWKRMSAKFNYIIEQI 398
Query: 328 QENEVQLTLSCLQLANSKVIKQWRDTDHKITFCYNEAKDNAKFVQAMEKCCHSLYLDDPV 387
+ + ++ L +A+SK++K WRD D +IT NE+KDN +++ +EK C LY D V
Sbjct: 399 KGPSCKAVINVLNVAHSKLLKNWRDLDARITDTANESKDNVRYLYTLEKVCQPLYNHDLV 458
Query: 388 KIKDSILSLLQTVRLIHSVSQFYNTSERISSLMVKITNQMIETCKQYITCRFKDTIWSQE 447
+ I +L+ +R+IH VS++YNTSER++SL +K+TNQM+ CK YIT + +W QE
Sbjct: 459 SMAHGIQNLINAIRMIHGVSRYYNTSERMTSLFIKVTNQMVTACKAYITDGGLNHVWDQE 518
Query: 448 RSLVRDKLIHCINLNRTYRETYIFVKNHPFLPNT---EQFSFSENYVFGKFDTFCKRLNK 504
+V K+ CI L + Y+ + F K + + + F SE Y+FGKF+ FCKRL K
Sbjct: 519 TPVVLKKIQDCIFLFKEYQAS--FHKTRKLISESSGEKSFEVSEMYIFGKFEAFCKRLEK 576
Query: 505 IIAMFDLTDDYNYLFEKRMXXXXXXXXXXXAVHTFEEAKKAVTTCQYDYLDYRNNEFDKD 564
I M + Y+ L + F + V QYD LD R EFD D
Sbjct: 577 ITEMITVVQTYSTLSNSTIEGIDIMAI------KFRNIYQGVKKKQYDILDPRRTEFDTD 630
Query: 565 YHAFEDKINALKESIGCTIEENFSSVWETPQGIKFLTRFEKVS 607
+ F KIN L+ I + +F + + Q ++ L RF+K++
Sbjct: 631 FLDFMTKINGLEVQIQAFMNSSFGKILSSQQALQLLQRFQKLN 673
Score = 64.9 bits (151), Expect = 1e-09
Identities = 53/249 (21%), Positives = 103/249 (41%), Gaps = 2/249 (0%)
Query: 617 RIKWSRCLMQNMIEIVESVCAHPVLRGLPASADMMRKYTNTRTLMNNYEDMMKAVWMNQN 676
+I W R L + + E + + + P ++R+Y ++ +E + W+ +
Sbjct: 722 KILWVRQLYRRISEPINYFFKNSDILSSPDGKAVIRQYNKISYVLVEFEVVYHTAWIRE- 780
Query: 677 LWDVDESLNNSL-LKIDETGCVAVNLDKNIKLLIRESDCLVKMGVPLPIVCHSLYAKKYY 735
+ + +L +L ++ ETG + VN D I ++RE+ C++KM + +P L +
Sbjct: 781 ISQLHYALQATLFVRHPETGKLLVNFDPKILEVVRETKCMIKMKLDVPEQAKRLLKLESK 840
Query: 736 FTLVNDSLQFLLEDYLRTVRRVKLEVRPLFLPQXXXXXXXXXXXXXXXCWTSEGWKEFID 795
LQ LL+ Y + V L P+ W+S + F
Sbjct: 841 LKADKLYLQGLLQYYDELCQEVPSVFVNLMTPKMKKVESVLRQGLTVLTWSSLTLESFFQ 900
Query: 796 RANAAIKSFDVLVTRVHDIYTNRIIYMLSGMQEVTLITLPEETPWSVQEFVEKVESGCRN 855
+ F+ L+ ++ D+ I +L + + LI+LPE V++ + E+ +
Sbjct: 901 EVELVLDMFNQLLKKISDLCEMHIDTVLKEIAKTVLISLPESGATKVEDMLTLNETYTKE 960
Query: 856 ACVELNRKS 864
LN KS
Sbjct: 961 WADILNHKS 969
>AL353700-2|CAI20293.1| 4176|Homo sapiens dynein, axonemal, heavy
chain 8 protein.
Length = 4176
Score = 252 bits (618), Expect = 4e-66
Identities = 165/583 (28%), Positives = 283/583 (48%), Gaps = 55/583 (9%)
Query: 39 MDPRLEFTFQLLIDGTGLPRHAIMDHVFEGNMLDDINQLFLPHMRNKLLWYYQ--DVEEI 96
+DP ++ F++L + GL + + + + L+ F L + YQ DV I
Sbjct: 132 IDPSYKYIFEILAENLGLDIVTVEELILDCPSLEAFTNFFAKDGCKTLKFLYQEGDVPGI 191
Query: 97 E-QRPVPENTKSRQQGKQPPPQVTWKRKLFLSDGWDVKFTGVCIYMFRINVSKQLPEEGF 155
E R + TK + KL++ + K G+CI+ R + +
Sbjct: 192 ECGRTIAGATKGAKM-----------MKLYIDNAAPDKLKGLCIFFVRCRNDVAINVKTI 240
Query: 156 HKDLFCGILNAEKVGMVTAIERVMEHVYMSALA--------HPSSDGDEDETRFPIVKNQ 207
++ +L+A K G++ I ++ ++++ A+ + S G+ ++ F N+
Sbjct: 241 QEEALFTVLDASK-GLLNGIRDMLANIFLPAVLATNNWGALNQSKQGESEKHIFTETINR 299
Query: 208 LLPGLRSFCSALKVCEDVCNQVNLFEDGLALMAPIQDHTQLKDMAKNPNTITMLEERVTE 267
L SF ++ + ++ ++ + + ++ A N T+ LEE +
Sbjct: 300 YL----SFLDGARISIEGTVKLKTIDN--VNFSKLHTFEEVTAAASNSETVHQLEEVLMV 353
Query: 268 WIKKVMEVASLLIFPNHAFNDQILSESEQLRREVDSSGPQDELEYWKKRGAQFSQLVSYL 327
W K++ +Q+L ESEQ+R+E SGP ELE+WK+ A+F+ ++ +
Sbjct: 354 WYKQI---------------EQVLIESEQMRKEAGDSGPLTELEHWKRMSAKFNYIIEQI 398
Query: 328 QENEVQLTLSCLQLANSKVIKQWRDTDHKITFCYNEAKDNAKFVQAMEKCCHSLYLDDPV 387
+ + ++ L +A+SK++K WRD D +IT NE+KDN +++ +EK C LY D V
Sbjct: 399 KGPSCKAVINVLNVAHSKLLKNWRDLDARITDTANESKDNVRYLYTLEKVCQPLYNHDLV 458
Query: 388 KIKDSILSLLQTVRLIHSVSQFYNTSERISSLMVKITNQMIETCKQYITCRFKDTIWSQE 447
+ I +L+ +R+IH VS++YNTSER++SL +K+TNQM+ CK YIT + +W QE
Sbjct: 459 SMAHGIQNLINAIRMIHGVSRYYNTSERMTSLFIKVTNQMVTACKAYITDGGLNHVWDQE 518
Query: 448 RSLVRDKLIHCINLNRTYRETYIFVKNHPFLPNT---EQFSFSENYVFGKFDTFCKRLNK 504
+V K+ CI L + Y+ + F K + + + F SE Y+FGKF+ FCKRL K
Sbjct: 519 TPVVLKKIQDCIFLFKEYQAS--FHKTRKLISESSGEKSFEVSEMYIFGKFEAFCKRLEK 576
Query: 505 IIAMFDLTDDYNYLFEKRMXXXXXXXXXXXAVHTFEEAKKAVTTCQYDYLDYRNNEFDKD 564
I M + Y+ L + F + V QYD LD R EFD D
Sbjct: 577 ITEMITVVQTYSTLSNSTIEGIDIMAI------KFRNIYQGVKKKQYDILDPRRTEFDTD 630
Query: 565 YHAFEDKINALKESIGCTIEENFSSVWETPQGIKFLTRFEKVS 607
+ F KIN L+ I + +F + + Q ++ L RF+K++
Sbjct: 631 FLDFMTKINGLEVQIQAFMNSSFGKILSSQQALQLLQRFQKLN 673
Score = 64.9 bits (151), Expect = 1e-09
Identities = 53/249 (21%), Positives = 103/249 (41%), Gaps = 2/249 (0%)
Query: 617 RIKWSRCLMQNMIEIVESVCAHPVLRGLPASADMMRKYTNTRTLMNNYEDMMKAVWMNQN 676
+I W R L + + E + + + P ++R+Y ++ +E + W+ +
Sbjct: 722 KILWVRQLYRRISEPINYFFKNSDILSSPDGKAVIRQYNKISYVLVEFEVVYHTAWIRE- 780
Query: 677 LWDVDESLNNSL-LKIDETGCVAVNLDKNIKLLIRESDCLVKMGVPLPIVCHSLYAKKYY 735
+ + +L +L ++ ETG + VN D I ++RE+ C++KM + +P L +
Sbjct: 781 ISQLHYALQATLFVRHPETGKLLVNFDPKILEVVRETKCMIKMKLDVPEQAKRLLKLESK 840
Query: 736 FTLVNDSLQFLLEDYLRTVRRVKLEVRPLFLPQXXXXXXXXXXXXXXXCWTSEGWKEFID 795
LQ LL+ Y + V L P+ W+S + F
Sbjct: 841 LKADKLYLQGLLQYYDELCQEVPSVFVNLMTPKMKKVESVLRQGLTVLTWSSLTLESFFQ 900
Query: 796 RANAAIKSFDVLVTRVHDIYTNRIIYMLSGMQEVTLITLPEETPWSVQEFVEKVESGCRN 855
+ F+ L+ ++ D+ I +L + + LI+LPE V++ + E+ +
Sbjct: 901 EVELVLDMFNQLLKKISDLCEMHIDTVLKEIAKTVLISLPESGATKVEDMLTLNETYTKE 960
Query: 856 ACVELNRKS 864
LN KS
Sbjct: 961 WADILNHKS 969
>AL035690-5|CAI19770.1| 4695|Homo sapiens dynein, axonemal, heavy
chain 8 protein.
Length = 4695
Score = 252 bits (618), Expect = 4e-66
Identities = 165/583 (28%), Positives = 283/583 (48%), Gaps = 55/583 (9%)
Query: 39 MDPRLEFTFQLLIDGTGLPRHAIMDHVFEGNMLDDINQLFLPHMRNKLLWYYQ--DVEEI 96
+DP ++ F++L + GL + + + + L+ F L + YQ DV I
Sbjct: 132 IDPSYKYIFEILAENLGLDIVTVEELILDCPSLEAFTNFFAKDGCKTLKFLYQEGDVPGI 191
Query: 97 E-QRPVPENTKSRQQGKQPPPQVTWKRKLFLSDGWDVKFTGVCIYMFRINVSKQLPEEGF 155
E R + TK + KL++ + K G+CI+ R + +
Sbjct: 192 ECGRTIAGATKGAKM-----------MKLYIDNAAPDKLKGLCIFFVRCRNDVAINVKTI 240
Query: 156 HKDLFCGILNAEKVGMVTAIERVMEHVYMSALA--------HPSSDGDEDETRFPIVKNQ 207
++ +L+A K G++ I ++ ++++ A+ + S G+ ++ F N+
Sbjct: 241 QEEALFTVLDASK-GLLNGIRDMLANIFLPAVLATNNWGALNQSKQGESEKHIFTETINR 299
Query: 208 LLPGLRSFCSALKVCEDVCNQVNLFEDGLALMAPIQDHTQLKDMAKNPNTITMLEERVTE 267
L SF ++ + ++ ++ + + ++ A N T+ LEE +
Sbjct: 300 YL----SFLDGARISIEGTVKLKTIDN--VNFSKLHTFEEVTAAASNSETVHQLEEVLMV 353
Query: 268 WIKKVMEVASLLIFPNHAFNDQILSESEQLRREVDSSGPQDELEYWKKRGAQFSQLVSYL 327
W K++ +Q+L ESEQ+R+E SGP ELE+WK+ A+F+ ++ +
Sbjct: 354 WYKQI---------------EQVLIESEQMRKEAGDSGPLTELEHWKRMSAKFNYIIEQI 398
Query: 328 QENEVQLTLSCLQLANSKVIKQWRDTDHKITFCYNEAKDNAKFVQAMEKCCHSLYLDDPV 387
+ + ++ L +A+SK++K WRD D +IT NE+KDN +++ +EK C LY D V
Sbjct: 399 KGPSCKAVINVLNVAHSKLLKNWRDLDARITDTANESKDNVRYLYTLEKVCQPLYNHDLV 458
Query: 388 KIKDSILSLLQTVRLIHSVSQFYNTSERISSLMVKITNQMIETCKQYITCRFKDTIWSQE 447
+ I +L+ +R+IH VS++YNTSER++SL +K+TNQM+ CK YIT + +W QE
Sbjct: 459 SMAHGIQNLINAIRMIHGVSRYYNTSERMTSLFIKVTNQMVTACKAYITDGGLNHVWDQE 518
Query: 448 RSLVRDKLIHCINLNRTYRETYIFVKNHPFLPNT---EQFSFSENYVFGKFDTFCKRLNK 504
+V K+ CI L + Y+ + F K + + + F SE Y+FGKF+ FCKRL K
Sbjct: 519 TPVVLKKIQDCIFLFKEYQAS--FHKTRKLISESSGEKSFEVSEMYIFGKFEAFCKRLEK 576
Query: 505 IIAMFDLTDDYNYLFEKRMXXXXXXXXXXXAVHTFEEAKKAVTTCQYDYLDYRNNEFDKD 564
I M + Y+ L + F + V QYD LD R EFD D
Sbjct: 577 ITEMITVVQTYSTLSNSTIEGIDIMAI------KFRNIYQGVKKKQYDILDPRRTEFDTD 630
Query: 565 YHAFEDKINALKESIGCTIEENFSSVWETPQGIKFLTRFEKVS 607
+ F KIN L+ I + +F + + Q ++ L RF+K++
Sbjct: 631 FLDFMTKINGLEVQIQAFMNSSFGKILSSQQALQLLQRFQKLN 673
Score = 64.9 bits (151), Expect = 1e-09
Identities = 53/249 (21%), Positives = 103/249 (41%), Gaps = 2/249 (0%)
Query: 617 RIKWSRCLMQNMIEIVESVCAHPVLRGLPASADMMRKYTNTRTLMNNYEDMMKAVWMNQN 676
+I W R L + + E + + + P ++R+Y ++ +E + W+ +
Sbjct: 722 KILWVRQLYRRISEPINYFFKNSDILSSPDGKAVIRQYNKISYVLVEFEVVYHTAWIRE- 780
Query: 677 LWDVDESLNNSL-LKIDETGCVAVNLDKNIKLLIRESDCLVKMGVPLPIVCHSLYAKKYY 735
+ + +L +L ++ ETG + VN D I ++RE+ C++KM + +P L +
Sbjct: 781 ISQLHYALQATLFVRHPETGKLLVNFDPKILEVVRETKCMIKMKLDVPEQAKRLLKLESK 840
Query: 736 FTLVNDSLQFLLEDYLRTVRRVKLEVRPLFLPQXXXXXXXXXXXXXXXCWTSEGWKEFID 795
LQ LL+ Y + V L P+ W+S + F
Sbjct: 841 LKADKLYLQGLLQYYDELCQEVPSVFVNLMTPKMKKVESVLRQGLTVLTWSSLTLESFFQ 900
Query: 796 RANAAIKSFDVLVTRVHDIYTNRIIYMLSGMQEVTLITLPEETPWSVQEFVEKVESGCRN 855
+ F+ L+ ++ D+ I +L + + LI+LPE V++ + E+ +
Sbjct: 901 EVELVLDMFNQLLKKISDLCEMHIDTVLKEIAKTVLISLPESGATKVEDMLTLNETYTKE 960
Query: 856 ACVELNRKS 864
LN KS
Sbjct: 961 WADILNHKS 969
>AL035555-4|CAI19822.1| 4695|Homo sapiens dynein, axonemal, heavy
chain 8 protein.
Length = 4695
Score = 252 bits (618), Expect = 4e-66
Identities = 165/583 (28%), Positives = 283/583 (48%), Gaps = 55/583 (9%)
Query: 39 MDPRLEFTFQLLIDGTGLPRHAIMDHVFEGNMLDDINQLFLPHMRNKLLWYYQ--DVEEI 96
+DP ++ F++L + GL + + + + L+ F L + YQ DV I
Sbjct: 132 IDPSYKYIFEILAENLGLDIVTVEELILDCPSLEAFTNFFAKDGCKTLKFLYQEGDVPGI 191
Query: 97 E-QRPVPENTKSRQQGKQPPPQVTWKRKLFLSDGWDVKFTGVCIYMFRINVSKQLPEEGF 155
E R + TK + KL++ + K G+CI+ R + +
Sbjct: 192 ECGRTIAGATKGAKM-----------MKLYIDNAAPDKLKGLCIFFVRCRNDVAINVKTI 240
Query: 156 HKDLFCGILNAEKVGMVTAIERVMEHVYMSALA--------HPSSDGDEDETRFPIVKNQ 207
++ +L+A K G++ I ++ ++++ A+ + S G+ ++ F N+
Sbjct: 241 QEEALFTVLDASK-GLLNGIRDMLANIFLPAVLATNNWGALNQSKQGESEKHIFTETINR 299
Query: 208 LLPGLRSFCSALKVCEDVCNQVNLFEDGLALMAPIQDHTQLKDMAKNPNTITMLEERVTE 267
L SF ++ + ++ ++ + + ++ A N T+ LEE +
Sbjct: 300 YL----SFLDGARISIEGTVKLKTIDN--VNFSKLHTFEEVTAAASNSETVHQLEEVLMV 353
Query: 268 WIKKVMEVASLLIFPNHAFNDQILSESEQLRREVDSSGPQDELEYWKKRGAQFSQLVSYL 327
W K++ +Q+L ESEQ+R+E SGP ELE+WK+ A+F+ ++ +
Sbjct: 354 WYKQI---------------EQVLIESEQMRKEAGDSGPLTELEHWKRMSAKFNYIIEQI 398
Query: 328 QENEVQLTLSCLQLANSKVIKQWRDTDHKITFCYNEAKDNAKFVQAMEKCCHSLYLDDPV 387
+ + ++ L +A+SK++K WRD D +IT NE+KDN +++ +EK C LY D V
Sbjct: 399 KGPSCKAVINVLNVAHSKLLKNWRDLDARITDTANESKDNVRYLYTLEKVCQPLYNHDLV 458
Query: 388 KIKDSILSLLQTVRLIHSVSQFYNTSERISSLMVKITNQMIETCKQYITCRFKDTIWSQE 447
+ I +L+ +R+IH VS++YNTSER++SL +K+TNQM+ CK YIT + +W QE
Sbjct: 459 SMAHGIQNLINAIRMIHGVSRYYNTSERMTSLFIKVTNQMVTACKAYITDGGLNHVWDQE 518
Query: 448 RSLVRDKLIHCINLNRTYRETYIFVKNHPFLPNT---EQFSFSENYVFGKFDTFCKRLNK 504
+V K+ CI L + Y+ + F K + + + F SE Y+FGKF+ FCKRL K
Sbjct: 519 TPVVLKKIQDCIFLFKEYQAS--FHKTRKLISESSGEKSFEVSEMYIFGKFEAFCKRLEK 576
Query: 505 IIAMFDLTDDYNYLFEKRMXXXXXXXXXXXAVHTFEEAKKAVTTCQYDYLDYRNNEFDKD 564
I M + Y+ L + F + V QYD LD R EFD D
Sbjct: 577 ITEMITVVQTYSTLSNSTIEGIDIMAI------KFRNIYQGVKKKQYDILDPRRTEFDTD 630
Query: 565 YHAFEDKINALKESIGCTIEENFSSVWETPQGIKFLTRFEKVS 607
+ F KIN L+ I + +F + + Q ++ L RF+K++
Sbjct: 631 FLDFMTKINGLEVQIQAFMNSSFGKILSSQQALQLLQRFQKLN 673
Score = 64.9 bits (151), Expect = 1e-09
Identities = 53/249 (21%), Positives = 103/249 (41%), Gaps = 2/249 (0%)
Query: 617 RIKWSRCLMQNMIEIVESVCAHPVLRGLPASADMMRKYTNTRTLMNNYEDMMKAVWMNQN 676
+I W R L + + E + + + P ++R+Y ++ +E + W+ +
Sbjct: 722 KILWVRQLYRRISEPINYFFKNSDILSSPDGKAVIRQYNKISYVLVEFEVVYHTAWIRE- 780
Query: 677 LWDVDESLNNSL-LKIDETGCVAVNLDKNIKLLIRESDCLVKMGVPLPIVCHSLYAKKYY 735
+ + +L +L ++ ETG + VN D I ++RE+ C++KM + +P L +
Sbjct: 781 ISQLHYALQATLFVRHPETGKLLVNFDPKILEVVRETKCMIKMKLDVPEQAKRLLKLESK 840
Query: 736 FTLVNDSLQFLLEDYLRTVRRVKLEVRPLFLPQXXXXXXXXXXXXXXXCWTSEGWKEFID 795
LQ LL+ Y + V L P+ W+S + F
Sbjct: 841 LKADKLYLQGLLQYYDELCQEVPSVFVNLMTPKMKKVESVLRQGLTVLTWSSLTLESFFQ 900
Query: 796 RANAAIKSFDVLVTRVHDIYTNRIIYMLSGMQEVTLITLPEETPWSVQEFVEKVESGCRN 855
+ F+ L+ ++ D+ I +L + + LI+LPE V++ + E+ +
Sbjct: 901 EVELVLDMFNQLLKKISDLCEMHIDTVLKEIAKTVLISLPESGATKVEDMLTLNETYTKE 960
Query: 856 ACVELNRKS 864
LN KS
Sbjct: 961 WADILNHKS 969
>AL035555-3|CAI19821.1| 4176|Homo sapiens dynein, axonemal, heavy
chain 8 protein.
Length = 4176
Score = 252 bits (618), Expect = 4e-66
Identities = 165/583 (28%), Positives = 283/583 (48%), Gaps = 55/583 (9%)
Query: 39 MDPRLEFTFQLLIDGTGLPRHAIMDHVFEGNMLDDINQLFLPHMRNKLLWYYQ--DVEEI 96
+DP ++ F++L + GL + + + + L+ F L + YQ DV I
Sbjct: 132 IDPSYKYIFEILAENLGLDIVTVEELILDCPSLEAFTNFFAKDGCKTLKFLYQEGDVPGI 191
Query: 97 E-QRPVPENTKSRQQGKQPPPQVTWKRKLFLSDGWDVKFTGVCIYMFRINVSKQLPEEGF 155
E R + TK + KL++ + K G+CI+ R + +
Sbjct: 192 ECGRTIAGATKGAKM-----------MKLYIDNAAPDKLKGLCIFFVRCRNDVAINVKTI 240
Query: 156 HKDLFCGILNAEKVGMVTAIERVMEHVYMSALA--------HPSSDGDEDETRFPIVKNQ 207
++ +L+A K G++ I ++ ++++ A+ + S G+ ++ F N+
Sbjct: 241 QEEALFTVLDASK-GLLNGIRDMLANIFLPAVLATNNWGALNQSKQGESEKHIFTETINR 299
Query: 208 LLPGLRSFCSALKVCEDVCNQVNLFEDGLALMAPIQDHTQLKDMAKNPNTITMLEERVTE 267
L SF ++ + ++ ++ + + ++ A N T+ LEE +
Sbjct: 300 YL----SFLDGARISIEGTVKLKTIDN--VNFSKLHTFEEVTAAASNSETVHQLEEVLMV 353
Query: 268 WIKKVMEVASLLIFPNHAFNDQILSESEQLRREVDSSGPQDELEYWKKRGAQFSQLVSYL 327
W K++ +Q+L ESEQ+R+E SGP ELE+WK+ A+F+ ++ +
Sbjct: 354 WYKQI---------------EQVLIESEQMRKEAGDSGPLTELEHWKRMSAKFNYIIEQI 398
Query: 328 QENEVQLTLSCLQLANSKVIKQWRDTDHKITFCYNEAKDNAKFVQAMEKCCHSLYLDDPV 387
+ + ++ L +A+SK++K WRD D +IT NE+KDN +++ +EK C LY D V
Sbjct: 399 KGPSCKAVINVLNVAHSKLLKNWRDLDARITDTANESKDNVRYLYTLEKVCQPLYNHDLV 458
Query: 388 KIKDSILSLLQTVRLIHSVSQFYNTSERISSLMVKITNQMIETCKQYITCRFKDTIWSQE 447
+ I +L+ +R+IH VS++YNTSER++SL +K+TNQM+ CK YIT + +W QE
Sbjct: 459 SMAHGIQNLINAIRMIHGVSRYYNTSERMTSLFIKVTNQMVTACKAYITDGGLNHVWDQE 518
Query: 448 RSLVRDKLIHCINLNRTYRETYIFVKNHPFLPNT---EQFSFSENYVFGKFDTFCKRLNK 504
+V K+ CI L + Y+ + F K + + + F SE Y+FGKF+ FCKRL K
Sbjct: 519 TPVVLKKIQDCIFLFKEYQAS--FHKTRKLISESSGEKSFEVSEMYIFGKFEAFCKRLEK 576
Query: 505 IIAMFDLTDDYNYLFEKRMXXXXXXXXXXXAVHTFEEAKKAVTTCQYDYLDYRNNEFDKD 564
I M + Y+ L + F + V QYD LD R EFD D
Sbjct: 577 ITEMITVVQTYSTLSNSTIEGIDIMAI------KFRNIYQGVKKKQYDILDPRRTEFDTD 630
Query: 565 YHAFEDKINALKESIGCTIEENFSSVWETPQGIKFLTRFEKVS 607
+ F KIN L+ I + +F + + Q ++ L RF+K++
Sbjct: 631 FLDFMTKINGLEVQIQAFMNSSFGKILSSQQALQLLQRFQKLN 673
Score = 64.9 bits (151), Expect = 1e-09
Identities = 53/249 (21%), Positives = 103/249 (41%), Gaps = 2/249 (0%)
Query: 617 RIKWSRCLMQNMIEIVESVCAHPVLRGLPASADMMRKYTNTRTLMNNYEDMMKAVWMNQN 676
+I W R L + + E + + + P ++R+Y ++ +E + W+ +
Sbjct: 722 KILWVRQLYRRISEPINYFFKNSDILSSPDGKAVIRQYNKISYVLVEFEVVYHTAWIRE- 780
Query: 677 LWDVDESLNNSL-LKIDETGCVAVNLDKNIKLLIRESDCLVKMGVPLPIVCHSLYAKKYY 735
+ + +L +L ++ ETG + VN D I ++RE+ C++KM + +P L +
Sbjct: 781 ISQLHYALQATLFVRHPETGKLLVNFDPKILEVVRETKCMIKMKLDVPEQAKRLLKLESK 840
Query: 736 FTLVNDSLQFLLEDYLRTVRRVKLEVRPLFLPQXXXXXXXXXXXXXXXCWTSEGWKEFID 795
LQ LL+ Y + V L P+ W+S + F
Sbjct: 841 LKADKLYLQGLLQYYDELCQEVPSVFVNLMTPKMKKVESVLRQGLTVLTWSSLTLESFFQ 900
Query: 796 RANAAIKSFDVLVTRVHDIYTNRIIYMLSGMQEVTLITLPEETPWSVQEFVEKVESGCRN 855
+ F+ L+ ++ D+ I +L + + LI+LPE V++ + E+ +
Sbjct: 901 EVELVLDMFNQLLKKISDLCEMHIDTVLKEIAKTVLISLPESGATKVEDMLTLNETYTKE 960
Query: 856 ACVELNRKS 864
LN KS
Sbjct: 961 WADILNHKS 969
>AL034345-4|CAI42436.1| 4695|Homo sapiens dynein, axonemal, heavy
chain 8 protein.
Length = 4695
Score = 252 bits (618), Expect = 4e-66
Identities = 165/583 (28%), Positives = 283/583 (48%), Gaps = 55/583 (9%)
Query: 39 MDPRLEFTFQLLIDGTGLPRHAIMDHVFEGNMLDDINQLFLPHMRNKLLWYYQ--DVEEI 96
+DP ++ F++L + GL + + + + L+ F L + YQ DV I
Sbjct: 132 IDPSYKYIFEILAENLGLDIVTVEELILDCPSLEAFTNFFAKDGCKTLKFLYQEGDVPGI 191
Query: 97 E-QRPVPENTKSRQQGKQPPPQVTWKRKLFLSDGWDVKFTGVCIYMFRINVSKQLPEEGF 155
E R + TK + KL++ + K G+CI+ R + +
Sbjct: 192 ECGRTIAGATKGAKM-----------MKLYIDNAAPDKLKGLCIFFVRCRNDVAINVKTI 240
Query: 156 HKDLFCGILNAEKVGMVTAIERVMEHVYMSALA--------HPSSDGDEDETRFPIVKNQ 207
++ +L+A K G++ I ++ ++++ A+ + S G+ ++ F N+
Sbjct: 241 QEEALFTVLDASK-GLLNGIRDMLANIFLPAVLATNNWGALNQSKQGESEKHIFTETINR 299
Query: 208 LLPGLRSFCSALKVCEDVCNQVNLFEDGLALMAPIQDHTQLKDMAKNPNTITMLEERVTE 267
L SF ++ + ++ ++ + + ++ A N T+ LEE +
Sbjct: 300 YL----SFLDGARISIEGTVKLKTIDN--VNFSKLHTFEEVTAAASNSETVHQLEEVLMV 353
Query: 268 WIKKVMEVASLLIFPNHAFNDQILSESEQLRREVDSSGPQDELEYWKKRGAQFSQLVSYL 327
W K++ +Q+L ESEQ+R+E SGP ELE+WK+ A+F+ ++ +
Sbjct: 354 WYKQI---------------EQVLIESEQMRKEAGDSGPLTELEHWKRMSAKFNYIIEQI 398
Query: 328 QENEVQLTLSCLQLANSKVIKQWRDTDHKITFCYNEAKDNAKFVQAMEKCCHSLYLDDPV 387
+ + ++ L +A+SK++K WRD D +IT NE+KDN +++ +EK C LY D V
Sbjct: 399 KGPSCKAVINVLNVAHSKLLKNWRDLDARITDTANESKDNVRYLYTLEKVCQPLYNHDLV 458
Query: 388 KIKDSILSLLQTVRLIHSVSQFYNTSERISSLMVKITNQMIETCKQYITCRFKDTIWSQE 447
+ I +L+ +R+IH VS++YNTSER++SL +K+TNQM+ CK YIT + +W QE
Sbjct: 459 SMAHGIQNLINAIRMIHGVSRYYNTSERMTSLFIKVTNQMVTACKAYITDGGLNHVWDQE 518
Query: 448 RSLVRDKLIHCINLNRTYRETYIFVKNHPFLPNT---EQFSFSENYVFGKFDTFCKRLNK 504
+V K+ CI L + Y+ + F K + + + F SE Y+FGKF+ FCKRL K
Sbjct: 519 TPVVLKKIQDCIFLFKEYQAS--FHKTRKLISESSGEKSFEVSEMYIFGKFEAFCKRLEK 576
Query: 505 IIAMFDLTDDYNYLFEKRMXXXXXXXXXXXAVHTFEEAKKAVTTCQYDYLDYRNNEFDKD 564
I M + Y+ L + F + V QYD LD R EFD D
Sbjct: 577 ITEMITVVQTYSTLSNSTIEGIDIMAI------KFRNIYQGVKKKQYDILDPRRTEFDTD 630
Query: 565 YHAFEDKINALKESIGCTIEENFSSVWETPQGIKFLTRFEKVS 607
+ F KIN L+ I + +F + + Q ++ L RF+K++
Sbjct: 631 FLDFMTKINGLEVQIQAFMNSSFGKILSSQQALQLLQRFQKLN 673
Score = 64.9 bits (151), Expect = 1e-09
Identities = 53/249 (21%), Positives = 103/249 (41%), Gaps = 2/249 (0%)
Query: 617 RIKWSRCLMQNMIEIVESVCAHPVLRGLPASADMMRKYTNTRTLMNNYEDMMKAVWMNQN 676
+I W R L + + E + + + P ++R+Y ++ +E + W+ +
Sbjct: 722 KILWVRQLYRRISEPINYFFKNSDILSSPDGKAVIRQYNKISYVLVEFEVVYHTAWIRE- 780
Query: 677 LWDVDESLNNSL-LKIDETGCVAVNLDKNIKLLIRESDCLVKMGVPLPIVCHSLYAKKYY 735
+ + +L +L ++ ETG + VN D I ++RE+ C++KM + +P L +
Sbjct: 781 ISQLHYALQATLFVRHPETGKLLVNFDPKILEVVRETKCMIKMKLDVPEQAKRLLKLESK 840
Query: 736 FTLVNDSLQFLLEDYLRTVRRVKLEVRPLFLPQXXXXXXXXXXXXXXXCWTSEGWKEFID 795
LQ LL+ Y + V L P+ W+S + F
Sbjct: 841 LKADKLYLQGLLQYYDELCQEVPSVFVNLMTPKMKKVESVLRQGLTVLTWSSLTLESFFQ 900
Query: 796 RANAAIKSFDVLVTRVHDIYTNRIIYMLSGMQEVTLITLPEETPWSVQEFVEKVESGCRN 855
+ F+ L+ ++ D+ I +L + + LI+LPE V++ + E+ +
Sbjct: 901 EVELVLDMFNQLLKKISDLCEMHIDTVLKEIAKTVLISLPESGATKVEDMLTLNETYTKE 960
Query: 856 ACVELNRKS 864
LN KS
Sbjct: 961 WADILNHKS 969
>AL034345-3|CAI42435.1| 4176|Homo sapiens dynein, axonemal, heavy
chain 8 protein.
Length = 4176
Score = 252 bits (618), Expect = 4e-66
Identities = 165/583 (28%), Positives = 283/583 (48%), Gaps = 55/583 (9%)
Query: 39 MDPRLEFTFQLLIDGTGLPRHAIMDHVFEGNMLDDINQLFLPHMRNKLLWYYQ--DVEEI 96
+DP ++ F++L + GL + + + + L+ F L + YQ DV I
Sbjct: 132 IDPSYKYIFEILAENLGLDIVTVEELILDCPSLEAFTNFFAKDGCKTLKFLYQEGDVPGI 191
Query: 97 E-QRPVPENTKSRQQGKQPPPQVTWKRKLFLSDGWDVKFTGVCIYMFRINVSKQLPEEGF 155
E R + TK + KL++ + K G+CI+ R + +
Sbjct: 192 ECGRTIAGATKGAKM-----------MKLYIDNAAPDKLKGLCIFFVRCRNDVAINVKTI 240
Query: 156 HKDLFCGILNAEKVGMVTAIERVMEHVYMSALA--------HPSSDGDEDETRFPIVKNQ 207
++ +L+A K G++ I ++ ++++ A+ + S G+ ++ F N+
Sbjct: 241 QEEALFTVLDASK-GLLNGIRDMLANIFLPAVLATNNWGALNQSKQGESEKHIFTETINR 299
Query: 208 LLPGLRSFCSALKVCEDVCNQVNLFEDGLALMAPIQDHTQLKDMAKNPNTITMLEERVTE 267
L SF ++ + ++ ++ + + ++ A N T+ LEE +
Sbjct: 300 YL----SFLDGARISIEGTVKLKTIDN--VNFSKLHTFEEVTAAASNSETVHQLEEVLMV 353
Query: 268 WIKKVMEVASLLIFPNHAFNDQILSESEQLRREVDSSGPQDELEYWKKRGAQFSQLVSYL 327
W K++ +Q+L ESEQ+R+E SGP ELE+WK+ A+F+ ++ +
Sbjct: 354 WYKQI---------------EQVLIESEQMRKEAGDSGPLTELEHWKRMSAKFNYIIEQI 398
Query: 328 QENEVQLTLSCLQLANSKVIKQWRDTDHKITFCYNEAKDNAKFVQAMEKCCHSLYLDDPV 387
+ + ++ L +A+SK++K WRD D +IT NE+KDN +++ +EK C LY D V
Sbjct: 399 KGPSCKAVINVLNVAHSKLLKNWRDLDARITDTANESKDNVRYLYTLEKVCQPLYNHDLV 458
Query: 388 KIKDSILSLLQTVRLIHSVSQFYNTSERISSLMVKITNQMIETCKQYITCRFKDTIWSQE 447
+ I +L+ +R+IH VS++YNTSER++SL +K+TNQM+ CK YIT + +W QE
Sbjct: 459 SMAHGIQNLINAIRMIHGVSRYYNTSERMTSLFIKVTNQMVTACKAYITDGGLNHVWDQE 518
Query: 448 RSLVRDKLIHCINLNRTYRETYIFVKNHPFLPNT---EQFSFSENYVFGKFDTFCKRLNK 504
+V K+ CI L + Y+ + F K + + + F SE Y+FGKF+ FCKRL K
Sbjct: 519 TPVVLKKIQDCIFLFKEYQAS--FHKTRKLISESSGEKSFEVSEMYIFGKFEAFCKRLEK 576
Query: 505 IIAMFDLTDDYNYLFEKRMXXXXXXXXXXXAVHTFEEAKKAVTTCQYDYLDYRNNEFDKD 564
I M + Y+ L + F + V QYD LD R EFD D
Sbjct: 577 ITEMITVVQTYSTLSNSTIEGIDIMAI------KFRNIYQGVKKKQYDILDPRRTEFDTD 630
Query: 565 YHAFEDKINALKESIGCTIEENFSSVWETPQGIKFLTRFEKVS 607
+ F KIN L+ I + +F + + Q ++ L RF+K++
Sbjct: 631 FLDFMTKINGLEVQIQAFMNSSFGKILSSQQALQLLQRFQKLN 673
Score = 64.9 bits (151), Expect = 1e-09
Identities = 53/249 (21%), Positives = 103/249 (41%), Gaps = 2/249 (0%)
Query: 617 RIKWSRCLMQNMIEIVESVCAHPVLRGLPASADMMRKYTNTRTLMNNYEDMMKAVWMNQN 676
+I W R L + + E + + + P ++R+Y ++ +E + W+ +
Sbjct: 722 KILWVRQLYRRISEPINYFFKNSDILSSPDGKAVIRQYNKISYVLVEFEVVYHTAWIRE- 780
Query: 677 LWDVDESLNNSL-LKIDETGCVAVNLDKNIKLLIRESDCLVKMGVPLPIVCHSLYAKKYY 735
+ + +L +L ++ ETG + VN D I ++RE+ C++KM + +P L +
Sbjct: 781 ISQLHYALQATLFVRHPETGKLLVNFDPKILEVVRETKCMIKMKLDVPEQAKRLLKLESK 840
Query: 736 FTLVNDSLQFLLEDYLRTVRRVKLEVRPLFLPQXXXXXXXXXXXXXXXCWTSEGWKEFID 795
LQ LL+ Y + V L P+ W+S + F
Sbjct: 841 LKADKLYLQGLLQYYDELCQEVPSVFVNLMTPKMKKVESVLRQGLTVLTWSSLTLESFFQ 900
Query: 796 RANAAIKSFDVLVTRVHDIYTNRIIYMLSGMQEVTLITLPEETPWSVQEFVEKVESGCRN 855
+ F+ L+ ++ D+ I +L + + LI+LPE V++ + E+ +
Sbjct: 901 EVELVLDMFNQLLKKISDLCEMHIDTVLKEIAKTVLISLPESGATKVEDMLTLNETYTKE 960
Query: 856 ACVELNRKS 864
LN KS
Sbjct: 961 WADILNHKS 969
>AL353700-1|CAI20292.1| 4490|Homo sapiens dynein, axonemal, heavy
chain 8 protein.
Length = 4490
Score = 246 bits (603), Expect = 2e-64
Identities = 147/496 (29%), Positives = 251/496 (50%), Gaps = 41/496 (8%)
Query: 123 KLFLSDGWDVKFTGVCIYMFRINVSKQLPEEGFHKDLFCGILNAEKVGMVTAIERVMEHV 182
KL++ + K G+CI+ R + + ++ +L+A K G++ I ++ ++
Sbjct: 3 KLYIDNAAPDKLKGLCIFFVRCRNDVAINVKTIQEEALFTVLDASK-GLLNGIRDMLANI 61
Query: 183 YMSALA--------HPSSDGDEDETRFPIVKNQLLPGLRSFCSALKVCEDVCNQVNLFED 234
++ A+ + S G+ ++ F N+ L SF ++ + ++ ++
Sbjct: 62 FLPAVLATNNWGALNQSKQGESEKHIFTETINRYL----SFLDGARISIEGTVKLKTIDN 117
Query: 235 GLALMAPIQDHTQLKDMAKNPNTITMLEERVTEWIKKVMEVASLLIFPNHAFNDQILSES 294
+ + ++ A N T+ LEE + W K++ +Q+L ES
Sbjct: 118 --VNFSKLHTFEEVTAAASNSETVHQLEEVLMVWYKQI---------------EQVLIES 160
Query: 295 EQLRREVDSSGPQDELEYWKKRGAQFSQLVSYLQENEVQLTLSCLQLANSKVIKQWRDTD 354
EQ+R+E SGP ELE+WK+ A+F+ ++ ++ + ++ L +A+SK++K WRD D
Sbjct: 161 EQMRKEAGDSGPLTELEHWKRMSAKFNYIIEQIKGPSCKAVINVLNVAHSKLLKNWRDLD 220
Query: 355 HKITFCYNEAKDNAKFVQAMEKCCHSLYLDDPVKIKDSILSLLQTVRLIHSVSQFYNTSE 414
+IT NE+KDN +++ +EK C LY D V + I +L+ +R+IH VS++YNTSE
Sbjct: 221 ARITDTANESKDNVRYLYTLEKVCQPLYNHDLVSMAHGIQNLINAIRMIHGVSRYYNTSE 280
Query: 415 RISSLMVKITNQMIETCKQYITCRFKDTIWSQERSLVRDKLIHCINLNRTYRETYIFVKN 474
R++SL +K+TNQM+ CK YIT + +W QE +V K+ CI L + Y+ + F K
Sbjct: 281 RMTSLFIKVTNQMVTACKAYITDGGLNHVWDQETPVVLKKIQDCIFLFKEYQAS--FHKT 338
Query: 475 HPFLPNT---EQFSFSENYVFGKFDTFCKRLNKIIAMFDLTDDYNYLFEKRMXXXXXXXX 531
+ + + F SE Y+FGKF+ FCKRL KI M + Y+ L +
Sbjct: 339 RKLISESSGEKSFEVSEMYIFGKFEAFCKRLEKITEMITVVQTYSTLSNSTIEGIDIMAI 398
Query: 532 XXXAVHTFEEAKKAVTTCQYDYLDYRNNEFDKDYHAFEDKINALKESIGCTIEENFSSVW 591
F + V QYD LD R EFD D+ F KIN L+ I + +F +
Sbjct: 399 ------KFRNIYQGVKKKQYDILDPRRTEFDTDFLDFMTKINGLEVQIQAFMNSSFGKIL 452
Query: 592 ETPQGIKFLTRFEKVS 607
+ Q ++ L RF+K++
Sbjct: 453 SSQQALQLLQRFQKLN 468
Score = 64.9 bits (151), Expect = 1e-09
Identities = 53/249 (21%), Positives = 103/249 (41%), Gaps = 2/249 (0%)
Query: 617 RIKWSRCLMQNMIEIVESVCAHPVLRGLPASADMMRKYTNTRTLMNNYEDMMKAVWMNQN 676
+I W R L + + E + + + P ++R+Y ++ +E + W+ +
Sbjct: 517 KILWVRQLYRRISEPINYFFKNSDILSSPDGKAVIRQYNKISYVLVEFEVVYHTAWIRE- 575
Query: 677 LWDVDESLNNSL-LKIDETGCVAVNLDKNIKLLIRESDCLVKMGVPLPIVCHSLYAKKYY 735
+ + +L +L ++ ETG + VN D I ++RE+ C++KM + +P L +
Sbjct: 576 ISQLHYALQATLFVRHPETGKLLVNFDPKILEVVRETKCMIKMKLDVPEQAKRLLKLESK 635
Query: 736 FTLVNDSLQFLLEDYLRTVRRVKLEVRPLFLPQXXXXXXXXXXXXXXXCWTSEGWKEFID 795
LQ LL+ Y + V L P+ W+S + F
Sbjct: 636 LKADKLYLQGLLQYYDELCQEVPSVFVNLMTPKMKKVESVLRQGLTVLTWSSLTLESFFQ 695
Query: 796 RANAAIKSFDVLVTRVHDIYTNRIIYMLSGMQEVTLITLPEETPWSVQEFVEKVESGCRN 855
+ F+ L+ ++ D+ I +L + + LI+LPE V++ + E+ +
Sbjct: 696 EVELVLDMFNQLLKKISDLCEMHIDTVLKEIAKTVLISLPESGATKVEDMLTLNETYTKE 755
Query: 856 ACVELNRKS 864
LN KS
Sbjct: 756 WADILNHKS 764
>AL035690-1|CAI19769.1| 4490|Homo sapiens dynein, axonemal, heavy
chain 8 protein.
Length = 4490
Score = 246 bits (603), Expect = 2e-64
Identities = 147/496 (29%), Positives = 251/496 (50%), Gaps = 41/496 (8%)
Query: 123 KLFLSDGWDVKFTGVCIYMFRINVSKQLPEEGFHKDLFCGILNAEKVGMVTAIERVMEHV 182
KL++ + K G+CI+ R + + ++ +L+A K G++ I ++ ++
Sbjct: 3 KLYIDNAAPDKLKGLCIFFVRCRNDVAINVKTIQEEALFTVLDASK-GLLNGIRDMLANI 61
Query: 183 YMSALA--------HPSSDGDEDETRFPIVKNQLLPGLRSFCSALKVCEDVCNQVNLFED 234
++ A+ + S G+ ++ F N+ L SF ++ + ++ ++
Sbjct: 62 FLPAVLATNNWGALNQSKQGESEKHIFTETINRYL----SFLDGARISIEGTVKLKTIDN 117
Query: 235 GLALMAPIQDHTQLKDMAKNPNTITMLEERVTEWIKKVMEVASLLIFPNHAFNDQILSES 294
+ + ++ A N T+ LEE + W K++ +Q+L ES
Sbjct: 118 --VNFSKLHTFEEVTAAASNSETVHQLEEVLMVWYKQI---------------EQVLIES 160
Query: 295 EQLRREVDSSGPQDELEYWKKRGAQFSQLVSYLQENEVQLTLSCLQLANSKVIKQWRDTD 354
EQ+R+E SGP ELE+WK+ A+F+ ++ ++ + ++ L +A+SK++K WRD D
Sbjct: 161 EQMRKEAGDSGPLTELEHWKRMSAKFNYIIEQIKGPSCKAVINVLNVAHSKLLKNWRDLD 220
Query: 355 HKITFCYNEAKDNAKFVQAMEKCCHSLYLDDPVKIKDSILSLLQTVRLIHSVSQFYNTSE 414
+IT NE+KDN +++ +EK C LY D V + I +L+ +R+IH VS++YNTSE
Sbjct: 221 ARITDTANESKDNVRYLYTLEKVCQPLYNHDLVSMAHGIQNLINAIRMIHGVSRYYNTSE 280
Query: 415 RISSLMVKITNQMIETCKQYITCRFKDTIWSQERSLVRDKLIHCINLNRTYRETYIFVKN 474
R++SL +K+TNQM+ CK YIT + +W QE +V K+ CI L + Y+ + F K
Sbjct: 281 RMTSLFIKVTNQMVTACKAYITDGGLNHVWDQETPVVLKKIQDCIFLFKEYQAS--FHKT 338
Query: 475 HPFLPNT---EQFSFSENYVFGKFDTFCKRLNKIIAMFDLTDDYNYLFEKRMXXXXXXXX 531
+ + + F SE Y+FGKF+ FCKRL KI M + Y+ L +
Sbjct: 339 RKLISESSGEKSFEVSEMYIFGKFEAFCKRLEKITEMITVVQTYSTLSNSTIEGIDIMAI 398
Query: 532 XXXAVHTFEEAKKAVTTCQYDYLDYRNNEFDKDYHAFEDKINALKESIGCTIEENFSSVW 591
F + V QYD LD R EFD D+ F KIN L+ I + +F +
Sbjct: 399 ------KFRNIYQGVKKKQYDILDPRRTEFDTDFLDFMTKINGLEVQIQAFMNSSFGKIL 452
Query: 592 ETPQGIKFLTRFEKVS 607
+ Q ++ L RF+K++
Sbjct: 453 SSQQALQLLQRFQKLN 468
Score = 64.9 bits (151), Expect = 1e-09
Identities = 53/249 (21%), Positives = 103/249 (41%), Gaps = 2/249 (0%)
Query: 617 RIKWSRCLMQNMIEIVESVCAHPVLRGLPASADMMRKYTNTRTLMNNYEDMMKAVWMNQN 676
+I W R L + + E + + + P ++R+Y ++ +E + W+ +
Sbjct: 517 KILWVRQLYRRISEPINYFFKNSDILSSPDGKAVIRQYNKISYVLVEFEVVYHTAWIRE- 575
Query: 677 LWDVDESLNNSL-LKIDETGCVAVNLDKNIKLLIRESDCLVKMGVPLPIVCHSLYAKKYY 735
+ + +L +L ++ ETG + VN D I ++RE+ C++KM + +P L +
Sbjct: 576 ISQLHYALQATLFVRHPETGKLLVNFDPKILEVVRETKCMIKMKLDVPEQAKRLLKLESK 635
Query: 736 FTLVNDSLQFLLEDYLRTVRRVKLEVRPLFLPQXXXXXXXXXXXXXXXCWTSEGWKEFID 795
LQ LL+ Y + V L P+ W+S + F
Sbjct: 636 LKADKLYLQGLLQYYDELCQEVPSVFVNLMTPKMKKVESVLRQGLTVLTWSSLTLESFFQ 695
Query: 796 RANAAIKSFDVLVTRVHDIYTNRIIYMLSGMQEVTLITLPEETPWSVQEFVEKVESGCRN 855
+ F+ L+ ++ D+ I +L + + LI+LPE V++ + E+ +
Sbjct: 696 EVELVLDMFNQLLKKISDLCEMHIDTVLKEIAKTVLISLPESGATKVEDMLTLNETYTKE 755
Query: 856 ACVELNRKS 864
LN KS
Sbjct: 756 WADILNHKS 764
>AL035555-1|CAI19819.1| 4490|Homo sapiens dynein, axonemal, heavy
chain 8 protein.
Length = 4490
Score = 246 bits (603), Expect = 2e-64
Identities = 147/496 (29%), Positives = 251/496 (50%), Gaps = 41/496 (8%)
Query: 123 KLFLSDGWDVKFTGVCIYMFRINVSKQLPEEGFHKDLFCGILNAEKVGMVTAIERVMEHV 182
KL++ + K G+CI+ R + + ++ +L+A K G++ I ++ ++
Sbjct: 3 KLYIDNAAPDKLKGLCIFFVRCRNDVAINVKTIQEEALFTVLDASK-GLLNGIRDMLANI 61
Query: 183 YMSALA--------HPSSDGDEDETRFPIVKNQLLPGLRSFCSALKVCEDVCNQVNLFED 234
++ A+ + S G+ ++ F N+ L SF ++ + ++ ++
Sbjct: 62 FLPAVLATNNWGALNQSKQGESEKHIFTETINRYL----SFLDGARISIEGTVKLKTIDN 117
Query: 235 GLALMAPIQDHTQLKDMAKNPNTITMLEERVTEWIKKVMEVASLLIFPNHAFNDQILSES 294
+ + ++ A N T+ LEE + W K++ +Q+L ES
Sbjct: 118 --VNFSKLHTFEEVTAAASNSETVHQLEEVLMVWYKQI---------------EQVLIES 160
Query: 295 EQLRREVDSSGPQDELEYWKKRGAQFSQLVSYLQENEVQLTLSCLQLANSKVIKQWRDTD 354
EQ+R+E SGP ELE+WK+ A+F+ ++ ++ + ++ L +A+SK++K WRD D
Sbjct: 161 EQMRKEAGDSGPLTELEHWKRMSAKFNYIIEQIKGPSCKAVINVLNVAHSKLLKNWRDLD 220
Query: 355 HKITFCYNEAKDNAKFVQAMEKCCHSLYLDDPVKIKDSILSLLQTVRLIHSVSQFYNTSE 414
+IT NE+KDN +++ +EK C LY D V + I +L+ +R+IH VS++YNTSE
Sbjct: 221 ARITDTANESKDNVRYLYTLEKVCQPLYNHDLVSMAHGIQNLINAIRMIHGVSRYYNTSE 280
Query: 415 RISSLMVKITNQMIETCKQYITCRFKDTIWSQERSLVRDKLIHCINLNRTYRETYIFVKN 474
R++SL +K+TNQM+ CK YIT + +W QE +V K+ CI L + Y+ + F K
Sbjct: 281 RMTSLFIKVTNQMVTACKAYITDGGLNHVWDQETPVVLKKIQDCIFLFKEYQAS--FHKT 338
Query: 475 HPFLPNT---EQFSFSENYVFGKFDTFCKRLNKIIAMFDLTDDYNYLFEKRMXXXXXXXX 531
+ + + F SE Y+FGKF+ FCKRL KI M + Y+ L +
Sbjct: 339 RKLISESSGEKSFEVSEMYIFGKFEAFCKRLEKITEMITVVQTYSTLSNSTIEGIDIMAI 398
Query: 532 XXXAVHTFEEAKKAVTTCQYDYLDYRNNEFDKDYHAFEDKINALKESIGCTIEENFSSVW 591
F + V QYD LD R EFD D+ F KIN L+ I + +F +
Sbjct: 399 ------KFRNIYQGVKKKQYDILDPRRTEFDTDFLDFMTKINGLEVQIQAFMNSSFGKIL 452
Query: 592 ETPQGIKFLTRFEKVS 607
+ Q ++ L RF+K++
Sbjct: 453 SSQQALQLLQRFQKLN 468
Score = 64.9 bits (151), Expect = 1e-09
Identities = 53/249 (21%), Positives = 103/249 (41%), Gaps = 2/249 (0%)
Query: 617 RIKWSRCLMQNMIEIVESVCAHPVLRGLPASADMMRKYTNTRTLMNNYEDMMKAVWMNQN 676
+I W R L + + E + + + P ++R+Y ++ +E + W+ +
Sbjct: 517 KILWVRQLYRRISEPINYFFKNSDILSSPDGKAVIRQYNKISYVLVEFEVVYHTAWIRE- 575
Query: 677 LWDVDESLNNSL-LKIDETGCVAVNLDKNIKLLIRESDCLVKMGVPLPIVCHSLYAKKYY 735
+ + +L +L ++ ETG + VN D I ++RE+ C++KM + +P L +
Sbjct: 576 ISQLHYALQATLFVRHPETGKLLVNFDPKILEVVRETKCMIKMKLDVPEQAKRLLKLESK 635
Query: 736 FTLVNDSLQFLLEDYLRTVRRVKLEVRPLFLPQXXXXXXXXXXXXXXXCWTSEGWKEFID 795
LQ LL+ Y + V L P+ W+S + F
Sbjct: 636 LKADKLYLQGLLQYYDELCQEVPSVFVNLMTPKMKKVESVLRQGLTVLTWSSLTLESFFQ 695
Query: 796 RANAAIKSFDVLVTRVHDIYTNRIIYMLSGMQEVTLITLPEETPWSVQEFVEKVESGCRN 855
+ F+ L+ ++ D+ I +L + + LI+LPE V++ + E+ +
Sbjct: 696 EVELVLDMFNQLLKKISDLCEMHIDTVLKEIAKTVLISLPESGATKVEDMLTLNETYTKE 755
Query: 856 ACVELNRKS 864
LN KS
Sbjct: 756 WADILNHKS 764
>AL034345-1|CAI42433.1| 4490|Homo sapiens dynein, axonemal, heavy
chain 8 protein.
Length = 4490
Score = 246 bits (603), Expect = 2e-64
Identities = 147/496 (29%), Positives = 251/496 (50%), Gaps = 41/496 (8%)
Query: 123 KLFLSDGWDVKFTGVCIYMFRINVSKQLPEEGFHKDLFCGILNAEKVGMVTAIERVMEHV 182
KL++ + K G+CI+ R + + ++ +L+A K G++ I ++ ++
Sbjct: 3 KLYIDNAAPDKLKGLCIFFVRCRNDVAINVKTIQEEALFTVLDASK-GLLNGIRDMLANI 61
Query: 183 YMSALA--------HPSSDGDEDETRFPIVKNQLLPGLRSFCSALKVCEDVCNQVNLFED 234
++ A+ + S G+ ++ F N+ L SF ++ + ++ ++
Sbjct: 62 FLPAVLATNNWGALNQSKQGESEKHIFTETINRYL----SFLDGARISIEGTVKLKTIDN 117
Query: 235 GLALMAPIQDHTQLKDMAKNPNTITMLEERVTEWIKKVMEVASLLIFPNHAFNDQILSES 294
+ + ++ A N T+ LEE + W K++ +Q+L ES
Sbjct: 118 --VNFSKLHTFEEVTAAASNSETVHQLEEVLMVWYKQI---------------EQVLIES 160
Query: 295 EQLRREVDSSGPQDELEYWKKRGAQFSQLVSYLQENEVQLTLSCLQLANSKVIKQWRDTD 354
EQ+R+E SGP ELE+WK+ A+F+ ++ ++ + ++ L +A+SK++K WRD D
Sbjct: 161 EQMRKEAGDSGPLTELEHWKRMSAKFNYIIEQIKGPSCKAVINVLNVAHSKLLKNWRDLD 220
Query: 355 HKITFCYNEAKDNAKFVQAMEKCCHSLYLDDPVKIKDSILSLLQTVRLIHSVSQFYNTSE 414
+IT NE+KDN +++ +EK C LY D V + I +L+ +R+IH VS++YNTSE
Sbjct: 221 ARITDTANESKDNVRYLYTLEKVCQPLYNHDLVSMAHGIQNLINAIRMIHGVSRYYNTSE 280
Query: 415 RISSLMVKITNQMIETCKQYITCRFKDTIWSQERSLVRDKLIHCINLNRTYRETYIFVKN 474
R++SL +K+TNQM+ CK YIT + +W QE +V K+ CI L + Y+ + F K
Sbjct: 281 RMTSLFIKVTNQMVTACKAYITDGGLNHVWDQETPVVLKKIQDCIFLFKEYQAS--FHKT 338
Query: 475 HPFLPNT---EQFSFSENYVFGKFDTFCKRLNKIIAMFDLTDDYNYLFEKRMXXXXXXXX 531
+ + + F SE Y+FGKF+ FCKRL KI M + Y+ L +
Sbjct: 339 RKLISESSGEKSFEVSEMYIFGKFEAFCKRLEKITEMITVVQTYSTLSNSTIEGIDIMAI 398
Query: 532 XXXAVHTFEEAKKAVTTCQYDYLDYRNNEFDKDYHAFEDKINALKESIGCTIEENFSSVW 591
F + V QYD LD R EFD D+ F KIN L+ I + +F +
Sbjct: 399 ------KFRNIYQGVKKKQYDILDPRRTEFDTDFLDFMTKINGLEVQIQAFMNSSFGKIL 452
Query: 592 ETPQGIKFLTRFEKVS 607
+ Q ++ L RF+K++
Sbjct: 453 SSQQALQLLQRFQKLN 468
Score = 64.9 bits (151), Expect = 1e-09
Identities = 53/249 (21%), Positives = 103/249 (41%), Gaps = 2/249 (0%)
Query: 617 RIKWSRCLMQNMIEIVESVCAHPVLRGLPASADMMRKYTNTRTLMNNYEDMMKAVWMNQN 676
+I W R L + + E + + + P ++R+Y ++ +E + W+ +
Sbjct: 517 KILWVRQLYRRISEPINYFFKNSDILSSPDGKAVIRQYNKISYVLVEFEVVYHTAWIRE- 575
Query: 677 LWDVDESLNNSL-LKIDETGCVAVNLDKNIKLLIRESDCLVKMGVPLPIVCHSLYAKKYY 735
+ + +L +L ++ ETG + VN D I ++RE+ C++KM + +P L +
Sbjct: 576 ISQLHYALQATLFVRHPETGKLLVNFDPKILEVVRETKCMIKMKLDVPEQAKRLLKLESK 635
Query: 736 FTLVNDSLQFLLEDYLRTVRRVKLEVRPLFLPQXXXXXXXXXXXXXXXCWTSEGWKEFID 795
LQ LL+ Y + V L P+ W+S + F
Sbjct: 636 LKADKLYLQGLLQYYDELCQEVPSVFVNLMTPKMKKVESVLRQGLTVLTWSSLTLESFFQ 695
Query: 796 RANAAIKSFDVLVTRVHDIYTNRIIYMLSGMQEVTLITLPEETPWSVQEFVEKVESGCRN 855
+ F+ L+ ++ D+ I +L + + LI+LPE V++ + E+ +
Sbjct: 696 EVELVLDMFNQLLKKISDLCEMHIDTVLKEIAKTVLISLPESGATKVEDMLTLNETYTKE 755
Query: 856 ACVELNRKS 864
LN KS
Sbjct: 756 WADILNHKS 764
>AF356519-1|AAK60620.1| 4490|Homo sapiens axonemal dynein heavy
chain 8 protein.
Length = 4490
Score = 246 bits (603), Expect = 2e-64
Identities = 147/496 (29%), Positives = 251/496 (50%), Gaps = 41/496 (8%)
Query: 123 KLFLSDGWDVKFTGVCIYMFRINVSKQLPEEGFHKDLFCGILNAEKVGMVTAIERVMEHV 182
KL++ + K G+CI+ R + + ++ +L+A K G++ I ++ ++
Sbjct: 3 KLYIDNAAPDKLKGLCIFFVRCRNDVAINVKTIQEEALFTVLDASK-GLLNGIRDMLANI 61
Query: 183 YMSALA--------HPSSDGDEDETRFPIVKNQLLPGLRSFCSALKVCEDVCNQVNLFED 234
++ A+ + S G+ ++ F N+ L SF ++ + ++ ++
Sbjct: 62 FLPAVLATNNWGALNQSKQGESEKHIFTETINRYL----SFLDGARISIEGTVKLKTIDN 117
Query: 235 GLALMAPIQDHTQLKDMAKNPNTITMLEERVTEWIKKVMEVASLLIFPNHAFNDQILSES 294
+ + ++ A N T+ LEE + W K++ +Q+L ES
Sbjct: 118 --VNFSKLHTFEEVTAAASNSETVHQLEEVLMVWYKQI---------------EQVLIES 160
Query: 295 EQLRREVDSSGPQDELEYWKKRGAQFSQLVSYLQENEVQLTLSCLQLANSKVIKQWRDTD 354
EQ+R+E SGP ELE+WK+ A+F+ ++ ++ + ++ L +A+SK++K WRD D
Sbjct: 161 EQMRKEAGDSGPLTELEHWKRMSAKFNYIIEQIKGPSCKAVINVLNVAHSKLLKNWRDLD 220
Query: 355 HKITFCYNEAKDNAKFVQAMEKCCHSLYLDDPVKIKDSILSLLQTVRLIHSVSQFYNTSE 414
+IT NE+KDN +++ +EK C LY D V + I +L+ +R+IH VS++YNTSE
Sbjct: 221 ARITDTANESKDNVRYLYTLEKVCQPLYNHDLVSMAHGIQNLINAIRMIHGVSRYYNTSE 280
Query: 415 RISSLMVKITNQMIETCKQYITCRFKDTIWSQERSLVRDKLIHCINLNRTYRETYIFVKN 474
R++SL +K+TNQM+ CK YIT + +W QE +V K+ CI L + Y+ + F K
Sbjct: 281 RMTSLFIKVTNQMVTACKAYITDGGLNHVWDQETPVVLKKIQDCIFLFKEYQAS--FHKT 338
Query: 475 HPFLPNT---EQFSFSENYVFGKFDTFCKRLNKIIAMFDLTDDYNYLFEKRMXXXXXXXX 531
+ + + F SE Y+FGKF+ FCKRL KI M + Y+ L +
Sbjct: 339 RKLISESSGEKSFEVSEMYIFGKFEAFCKRLEKITEMITVVQTYSTLSNSTIEGIDIMAI 398
Query: 532 XXXAVHTFEEAKKAVTTCQYDYLDYRNNEFDKDYHAFEDKINALKESIGCTIEENFSSVW 591
F + V QYD LD R EFD D+ F KIN L+ I + +F +
Sbjct: 399 ------KFRNIYQGVKKKQYDILDPRRTEFDTDFLDFMTKINGLEVQIQAFMNSSFGKIL 452
Query: 592 ETPQGIKFLTRFEKVS 607
+ Q ++ L RF+K++
Sbjct: 453 SSQQALQLLQRFQKLN 468
Score = 64.9 bits (151), Expect = 1e-09
Identities = 53/249 (21%), Positives = 103/249 (41%), Gaps = 2/249 (0%)
Query: 617 RIKWSRCLMQNMIEIVESVCAHPVLRGLPASADMMRKYTNTRTLMNNYEDMMKAVWMNQN 676
+I W R L + + E + + + P ++R+Y ++ +E + W+ +
Sbjct: 517 KILWVRQLYRRISEPINYFFKNSDILSSPDGKAVIRQYNKISYVLVEFEVVYHTAWVRE- 575
Query: 677 LWDVDESLNNSL-LKIDETGCVAVNLDKNIKLLIRESDCLVKMGVPLPIVCHSLYAKKYY 735
+ + +L +L ++ ETG + VN D I ++RE+ C++KM + +P L +
Sbjct: 576 ISQLHYALQATLFVRHPETGKLLVNFDPKILEVVRETKCMIKMKLDVPEQAKRLLKLESK 635
Query: 736 FTLVNDSLQFLLEDYLRTVRRVKLEVRPLFLPQXXXXXXXXXXXXXXXCWTSEGWKEFID 795
LQ LL+ Y + V L P+ W+S + F
Sbjct: 636 LKADKLYLQGLLQYYDELCQEVPSVFVNLMTPKMKKVESVLRQGLTVLTWSSLTLESFFQ 695
Query: 796 RANAAIKSFDVLVTRVHDIYTNRIIYMLSGMQEVTLITLPEETPWSVQEFVEKVESGCRN 855
+ F+ L+ ++ D+ I +L + + LI+LPE V++ + E+ +
Sbjct: 696 EVELVLDMFNQLLKKISDLCEMHIDTVLKEIAKTVLISLPESGATKVEDMLTLNETYTKE 755
Query: 856 ACVELNRKS 864
LN KS
Sbjct: 756 WADILNHKS 764
>AK125475-1|BAC86173.1| 913|Homo sapiens protein ( Homo sapiens
cDNA FLJ43486 fis, clone OCBBF3003592, weakly similar
to Dynein beta chain, flagellar outer arm. ).
Length = 913
Score = 95.9 bits (228), Expect = 6e-19
Identities = 126/646 (19%), Positives = 260/646 (40%), Gaps = 48/646 (7%)
Query: 220 KVCEDVCNQVNLFEDGLALMAPIQD-HTQLKDMAKNPNTITMLEERVTEWIKKVMEVASL 278
K ++ + E + L PI ++ D+A +P T+ +LE+ V W+ ++
Sbjct: 24 KFASNIQRTMQQLEGEIKLEMPIISVEGEVSDLAADPETVDILEQCVINWLNQISTAVEA 83
Query: 279 LIFPNHAFNDQILSESEQLRREVDSSGPQDELEYWKKRGAQFSQLVSYLQENEVQLTLSC 338
QL++ GP E+E+W++R A S L + V+ L
Sbjct: 84 -----------------QLKKTPQGKGPLAEIEFWRERNATLSALHEQTKLPIVRKVLDV 126
Query: 339 LQLANSKVIKQWRDTDHKITFCYNEAKDNAKFVQAMEKCCHSLYLDDPVK-IKDSILSLL 397
++ ++S ++ + ++ + EA DN +F+ +E+ ++ + D+I +++
Sbjct: 127 IKESDSMLVANLQPVFTELFKFHTEASDNVRFLSTVERYFKNITHGSGFHVVLDTIPAMM 186
Query: 398 QTVRLIHSVSQFYNTSERISSLMVKITNQMIETCKQYITCRFKDTIWSQERSLVRDKLIH 457
+R++ +S+ YN ER+ LM +I ++ E + + R T++ + R+ + K +
Sbjct: 187 SALRMVWIISRHYNKDERMIPLMERIAWEIAERVCRVVNLR---TLFKENRASAQSKTLE 243
Query: 458 CINLNRTYRETYIFVKNHPFLPNTE-QFSFSENYVFGKFD---TFCKRLNKIIAMFDLTD 513
N R +++ Y + E ++ F +F + D T C+ L+ ++ + L +
Sbjct: 244 ARNTLRLWKKAYFDTRAKIEASGREDRWEFDRKRLFERTDYMATICQDLSDVLQV--LEE 301
Query: 514 DYNYLFEKRMXXXXXXXXXXXAVHTFEEAKKAVTTCQYDYLDYRNNEFDKDYHAFEDKIN 573
YN + + + + +D ++++F K Y E KI
Sbjct: 302 FYNIFGPELKAVTGDPKRIDDVLCRVDGLVTPMENLTFDPFSIKSSQFWK-YVMDEFKIE 360
Query: 574 ALKESIGCTIEENFSSVWETPQGIKFLTRFEKVSQKI--QITKLRRIKWSRCLMQNMIEI 631
L + I +N E P K V+ I + + RIK + Q + EI
Sbjct: 361 VLIDIINKIFVQNL----ENPPLYK---NHPPVAGAIYWERSLFFRIKHTILRFQEVQEI 413
Query: 632 VESVCAHPVLRGLPASADMMRKYTNTR--TLMNNYEDMMKAVWMNQNLWDVDESLNNSLL 689
++S V + M++Y + + M E ++ A+ M ++L
Sbjct: 414 LDSDRGQEVKQKYLEVGRTMKEYEDRKYEQWMEVTEQVLPAL-MKKSLLTKSSIATEEPS 472
Query: 690 KIDETGCVAVNLDKNIKLLIRESDCLVKMGVPLPIVCHSLYAKKYYFTLVNDSLQFLLED 749
++ A+N ++ +I E+ L ++G +P + ++ ++ F +Q +L+
Sbjct: 473 TLERGAVFAINFSPALREIINETKYLEQLGFTVPELARNVALQEDKFLRYTAGIQRMLDH 532
Query: 750 YLRTVRRVKLEVRPLFLPQXXXXXXXXXXXXXXXCWTSEGWKEFIDRANAAIKSFDVLVT 809
Y + + L W S G ++I AI F+ LV
Sbjct: 533 YHMLIGTLNDAESVLLKDHSQELLRVFRSGYKRLNWNSLGIGDYITGCKQAIGKFESLVH 592
Query: 810 RVHDIYTNRIIYMLSGMQEVTLITLP-----EETPWSVQEFVEKVE 850
++H + I L+ ++ + L P EE P V+EF E +E
Sbjct: 593 QIHK-NADDISSRLTLIEAINLFKYPAAKSEEELP-GVKEFFEHIE 636
>AJ320497-1|CAC60121.1| 4523|Homo sapiens axonemal beta heavy chain
dynein type 11 protein.
Length = 4523
Score = 81.8 bits (193), Expect = 1e-14
Identities = 85/356 (23%), Positives = 145/356 (40%), Gaps = 14/356 (3%)
Query: 275 VASLLIFPNHAFNDQILSESEQLRREVDSSGPQDELEYWKKRGAQFSQLVSYLQENEVQL 334
+ S++I +H + I +S Q PQ EL++W R S + LQ V
Sbjct: 243 IESVVIEWSHQIQEIIERDSVQRLLNGLHLSPQAELDFWMMRRENLSCIYDQLQAPVVLK 302
Query: 335 TLSCLQLANSKVIKQWRDTDHKITFCYNEAKDNAKFVQAMEKCCHSLYLDDPVKIKDSIL 394
+ L S +D + EA+D +++ + + L + + + I
Sbjct: 303 MVKILTTKQSSYFPTLKDIFLAVENALLEAQDVELYLRPLRRHIQCLQETEFPQTRILIA 362
Query: 395 SLLQTVRLIHSVSQFYNTSERISSLMVKITNQMIETCKQYITCRFKDTIWSQ-ERSLVRD 453
L T+ LI S S+FYNT R+ L+ + N I Y++ +D + + E SL +
Sbjct: 363 PLFHTICLIWSHSKFYNTPARVIVLLQEFCNLFINQATAYLSP--EDLLRGEIEESL--E 418
Query: 454 KLIHCINLNRTYRETYIFVK----NHPFLPNTEQFSFSENYVFGKFDTFCKRLNKIIAMF 509
K+ +N+ +T++ ++ + ++ + F + VF +FD F RL KI +F
Sbjct: 419 KVQVAVNILKTFKNSFFNYRKKLASYFMGRKLRPWDFQSHLVFCRFDKFLDRLIKIEDIF 478
Query: 510 DLTDDYNYLFEKRMXXXXXXXXXXXAVHTFEEAK----KAVTTCQYDYLDYRNNEFDKDY 565
T ++ L E+ VH E K YD D N EF+ DY
Sbjct: 479 ATTLEFEKL-ERLEFGGTKGAILNGQVHEMSEELMELCKLFKQSTYDPSDCTNMEFESDY 537
Query: 566 HAFEDKINALKESIGCTIEENFSSVWETPQGIKFLTRFEKVSQKIQITKLRRIKWS 621
AF+ K +G I E F + K LT F +K + ++ + +S
Sbjct: 538 VAFKSKTLEFDRRLGTIICEAFFNCNGLEAAFKLLTIFGNFLEKPVVMEIFSLHYS 593
Score = 45.6 bits (103), Expect = 0.001
Identities = 44/198 (22%), Positives = 85/198 (42%), Gaps = 8/198 (4%)
Query: 618 IKWSRCLMQNMIEIVESVCAHPVL-RGLPASADMMRKYTNTRTLMNNYEDMMKAVWMNQN 676
+KW++ ++Q + + + L G P A + +KY TL++ +E + W N
Sbjct: 635 MKWAQQVLQRLQMFWSNFASLRYLFLGNPDHALVYQKYVEMTTLLDQFESRIYNEW-KSN 693
Query: 677 LWDVDE-SLNNSLLKIDE-TGCVAVNLDKNIKLLIRESDCLVKM-GVPLPIVCHSLYAKK 733
+ ++ E +LN L+K G + VN D + ++RE L+ + +P +++ K+
Sbjct: 694 VDEICEFNLNQPLVKFSAINGLLCVNFDPKLVAVLREVKYLLMLKKQDIPDSALAIFKKR 753
Query: 734 YYFTLVNDSLQFLLEDYLRTVRRVKLEVR-PLFLPQXXXXXXXXXXXXXXXCWTSEGWKE 792
+L L++ Y +++ LEV PL + W + W
Sbjct: 754 NTILKYIGNLDLLVQGY-NKLKQTLLEVEYPLIEDELRAIDEQLTAATTWLTWQDDCW-G 811
Query: 793 FIDRANAAIKSFDVLVTR 810
+I+R AA + V R
Sbjct: 812 YIERVRAATSELEHRVER 829
>AY050643-1|AAL14192.1| 200|Homo sapiens dynein heavy chain
protein.
Length = 200
Score = 80.6 bits (190), Expect = 3e-14
Identities = 50/189 (26%), Positives = 93/189 (49%), Gaps = 9/189 (4%)
Query: 39 MDPRLEFTFQLLIDGTGLPRHAIMDHVFEGNMLDDINQLFLPHMRNKLLWYYQDVEEIEQ 98
+D R + F ++ L + + D + EGN ++ I+QLF L++YYQDVEE E
Sbjct: 18 LDARHNYLFAIVASCLDLNKTEVEDAILEGNQIERIDQLFAVGGLRHLMFYYQDVEEAET 77
Query: 99 RPVPE-NTKSRQQGKQPPPQVTWKRKLFLSDGWDVKFTGVCIYMFRINVSKQLPEEGFHK 157
+ + GK P K+F+++G DV TGVC++ R + SK + + H+
Sbjct: 78 GQLGSLGGVNLVSGKIKKP------KVFVTEGNDVALTGVCVFFIRTDPSKAITPDNIHQ 131
Query: 158 DLFCGILNAEKVGMVTAIERVMEHVYMSALAHPSSDGDEDE--TRFPIVKNQLLPGLRSF 215
++ +L+A G++ ++ R++ +++ AL S E E ++ + L L F
Sbjct: 132 EVSFNMLDAADGGLLNSVRRLLSDIFIPALRATSHGWGELEGLQDAANIRQEFLSSLEGF 191
Query: 216 CSALKVCED 224
+ L ++
Sbjct: 192 VNVLSGAQE 200
>BC034225-1|AAH34225.1| 872|Homo sapiens DNAH2 protein protein.
Length = 872
Score = 80.2 bits (189), Expect = 3e-14
Identities = 71/335 (21%), Positives = 137/335 (40%), Gaps = 13/335 (3%)
Query: 289 QILSESEQLRREVDSSGPQDELEYWKKRGAQFSQLVSYLQENEVQLTLSCLQLANSKVIK 348
++LS E + ++ GP +E+E+W+ R S + L + V+ S L LA S +
Sbjct: 258 EMLSAQETVETG-ENLGPLEEIEFWRNRCMDLSGISKQLVKKGVKHVESILHLAKSSYLA 316
Query: 349 QWRDTDHKITFCYNEAKDNAKFVQAMEKCCHSLYLDDPVKIKDSILSLLQTVRLIHSVSQ 408
+ +I +A+ N F+ +++ L P I + L+ +R+I S
Sbjct: 317 PFMKLAQQIQDGSRQAQSNLTFLSILKEPYQELAFMKPKDISSKLPKLISLIRIIWVNSP 376
Query: 409 FYNTSERISSLMVKITNQMIETCKQYITCRFKDTIWSQERSLVRDKLIHCINLNRTYRET 468
YNT ER++SL K++N++I C I+ D I+ S ++ L CI +++
Sbjct: 377 HYNTRERLTSLFRKMSNEIIRLCCHAISL---DRIFEGYVSSSKEDLQGCILCCHAWKDH 433
Query: 469 YIFVKNHPFLPNTEQFSFSENYVFGKFDTFCKRLNKIIAMFDLTDDYNYLFEKRMXXXXX 528
Y+ ++ + + +F + D F +R +I + D + + +
Sbjct: 434 YVQAVQMHIQFSSRGWVLDQTSIFAQVDAFVQRCKDLIEVCDCQYHFARWEDGKQGPLPC 493
Query: 529 XXXXXXAVHT---------FEEAKKAVTTCQYDYLDYRNNEFDKDYHAFEDKINALKESI 579
T F + + + LD +N + +DY+ F I L+
Sbjct: 494 FFGAQGPQITRNLLEIEDIFHKNLHTLRAVRGGILDVKNTCWHEDYNKFRAGIKDLEVMT 553
Query: 580 GCTIEENFSSVWETPQGIKFLTRFEKVSQKIQITK 614
I F V + P G+ L F +++ + I +
Sbjct: 554 QNLITSAFELVRDVPHGVLLLDTFHRLASREAIKR 588
>AC102952-1|AAS07505.1| 453|Homo sapiens Homo sapiens dynein,
axonemal, heavy polypeptide 11 (DNAH11) protein.
Length = 453
Score = 77.4 bits (182), Expect = 2e-13
Identities = 79/322 (24%), Positives = 132/322 (40%), Gaps = 14/322 (4%)
Query: 275 VASLLIFPNHAFNDQILSESEQLRREVDSSGPQDELEYWKKRGAQFSQLVSYLQENEVQL 334
+ S++I +H + I +S Q PQ EL++W R S + LQ V
Sbjct: 126 IESVVIEWSHQIQEIIERDSVQRLLNGLHLSPQAELDFWMMRRENLSCIYDQLQAPVVLK 185
Query: 335 TLSCLQLANSKVIKQWRDTDHKITFCYNEAKDNAKFVQAMEKCCHSLYLDDPVKIKDSIL 394
+ L S +D + EA+D +++ + + L + + + I
Sbjct: 186 MVKILTTKQSSYFPTLKDIFLAVENALLEAQDVELYLRPLRRHIQCLQETEFPQTRILIA 245
Query: 395 SLLQTVRLIHSVSQFYNTSERISSLMVKITNQMIETCKQYITCRFKDTIWSQ-ERSLVRD 453
L T+ LI S S+FYNT R+ L+ + N I Y++ +D + + E SL +
Sbjct: 246 PLFHTICLIWSHSKFYNTPARVIVLLQEFCNLFINQATAYLSP--EDLLRGEIEESL--E 301
Query: 454 KLIHCINLNRTYRETYIFVK----NHPFLPNTEQFSFSENYVFGKFDTFCKRLNKIIAMF 509
K+ +N+ +T++ ++ + ++ + F + VF +FD F RL KI +F
Sbjct: 302 KVQVAVNILKTFKNSFFNYRKKLASYFMGRKLRPWDFQSHLVFCRFDKFLDRLIKIEDIF 361
Query: 510 DLTDDYNYLFEKRMXXXXXXXXXXXAVHTFEEAK----KAVTTCQYDYLDYRNNEFDKDY 565
T ++ L E+ VH E K YD D N EF+ DY
Sbjct: 362 ATTLEFEKL-ERLEFGGTKGAILNGQVHEMSEELMELCKLFKQSTYDPSDCTNMEFESDY 420
Query: 566 HAFEDKINALKESIGCTIEENF 587
AF+ K +G I E F
Sbjct: 421 VAFKSKTLEFDRRLGTIICEAF 442
>AJ404468-1|CAB94756.1| 4486|Homo sapiens axonemal dynein heavy
chain 9 protein.
Length = 4486
Score = 60.1 bits (139), Expect = 4e-08
Identities = 76/393 (19%), Positives = 155/393 (39%), Gaps = 16/393 (4%)
Query: 221 VCEDVCNQVNLFEDGLA-LMAPIQDHTQLKDMAKNPNT--ITMLEERVTEWIKK--VMEV 275
+CEDV + + L+ ++ ++ T L A + E V + I K + +
Sbjct: 158 ICEDVRRHAHSLQCDLSVILEQVKGKTLLPLPAGSEKMEFADSKSETVLDSIDKSVIYAI 217
Query: 276 ASLLIFPNHAFNDQILSESEQLRREVDSSGPQDELEYWKKRGAQFSQLVSYLQENEVQLT 335
S +I ++ + ES Q + ++ P+ ELE+WK R + + L+ V+
Sbjct: 218 ESAVIKWSYQVQVVLKRESSQPLLQGENPTPKVELEFWKSRYEDLKYIYNQLRTITVRGM 277
Query: 336 LSCLQLANSKVIKQWRDTDHKITFCYNEAKDNAKFVQAMEKCCHSLYLDDPVKIKDSILS 395
L S ++ + EA+D + +++ +L + ++K +
Sbjct: 278 AKLLDKLQSSYFPAFKAMYRDVVAALAEAQDIHVHLIPLQRHLEALENAEFPEVKPQLRP 337
Query: 396 LLQTVRLIHSVSQFYNTSERISSLMVKITNQMIETCKQYITCR--FKDTIWSQERSL--V 451
LL V LI + + Y + R++ L+ +I N +I+ Y++ + + +R L V
Sbjct: 338 LLHVVCLIWATCKSYRSPGRLTVLLQEICNLLIQQASNYLSPEDLLRSEVEESQRKLQVV 397
Query: 452 RDKLIHCINLNRTYRET-YIFVKNHPFLPNTEQFSFSENYVFGKFDTFCKRLNKIIAMFD 510
D L + RE + + K + +++ F + VF + D F RL+ + +
Sbjct: 398 SDTLSFFKQEFQDRRENLHTYFKEN---QEVKEWDFQSSLVFVRLDGFLGRLHVVEGLLK 454
Query: 511 LTDDYNYLFEKRMXXXXXXXXXXXA--VH-TFEEAKKAVTTCQYDYLDYRNNEFDKDYHA 567
D++ L + +H F+E + ++ D L ++ +F+ D
Sbjct: 455 TALDFHKLGKVEFSGVRGNALSQQVQQMHEEFQEMYRLLSGSSSDCLYLQSTDFENDVSE 514
Query: 568 FEDKINALKESIGCTIEENFSSVWETPQGIKFL 600
F K+ L +G + F K L
Sbjct: 515 FNQKVEDLDRRLGTIFIQAFDDAPGLEHAFKLL 547
Score = 38.7 bits (86), Expect = 0.10
Identities = 33/179 (18%), Positives = 74/179 (41%), Gaps = 5/179 (2%)
Query: 638 HPVLRGLPASADMMRKYTNTRTLMNNYEDMMKAVWMNQNLWDVDESLNNSLLKID-ETGC 696
HP + M +KY + +L+ YE + W +L+ LLK D ET
Sbjct: 633 HPCMESAEGKR-MQQKYEDMLSLLEKYETRLYEDWCRTVSEKSQYNLSQPLLKRDPETKE 691
Query: 697 VAVNLDKNIKLLIRESDCLVKMGVP-LPIVCHSLYAKKYYFTLVNDSLQFLLEDYLRTVR 755
+ +N + + +++E L + +P ++++ + ++ + +L+ L+ ++ V
Sbjct: 692 ITINFNPQLISVLKEMSYLEPREMKHMPETAAAMFSSRDFYRQLVANLE-LMANWYNKVM 750
Query: 756 RVKLEVR-PLFLPQXXXXXXXXXXXXXXXCWTSEGWKEFIDRANAAIKSFDVLVTRVHD 813
+ LEV PL + W +EG +++ ++I + + + D
Sbjct: 751 KTLLEVEFPLVEEELQNIDLRLRAAEETLNWKTEGICDYVTEITSSIHDLEQRIQKTKD 809
>AF257737-1|AAF69004.1| 4486|Homo sapiens ciliary dynein heavy chain
9 protein.
Length = 4486
Score = 60.1 bits (139), Expect = 4e-08
Identities = 76/393 (19%), Positives = 155/393 (39%), Gaps = 16/393 (4%)
Query: 221 VCEDVCNQVNLFEDGLA-LMAPIQDHTQLKDMAKNPNT--ITMLEERVTEWIKK--VMEV 275
+CEDV + + L+ ++ ++ T L A + E V + I K + +
Sbjct: 158 ICEDVRRHAHSLQCDLSVILEQVKGKTLLPLPAGSEKMEFADSKSETVLDSIDKSVIYAI 217
Query: 276 ASLLIFPNHAFNDQILSESEQLRREVDSSGPQDELEYWKKRGAQFSQLVSYLQENEVQLT 335
S +I ++ + ES Q + ++ P+ ELE+WK R + + L+ V+
Sbjct: 218 ESAVIKWSYQVQVVLKRESSQPLLQGENPTPKVELEFWKSRYEDLKYIYNQLRTITVRGM 277
Query: 336 LSCLQLANSKVIKQWRDTDHKITFCYNEAKDNAKFVQAMEKCCHSLYLDDPVKIKDSILS 395
L S ++ + EA+D + +++ +L + ++K +
Sbjct: 278 AKLLDKLQSSYFPAFKAMYRDVVAALAEAQDIHVHLIPLQRHLEALENAEFPEVKPQLRP 337
Query: 396 LLQTVRLIHSVSQFYNTSERISSLMVKITNQMIETCKQYITCR--FKDTIWSQERSL--V 451
LL V LI + + Y + R++ L+ +I N +I+ Y++ + + +R L V
Sbjct: 338 LLHVVCLIWATCKSYRSPGRLTVLLQEICNLLIQQASNYLSPEDLLRSEVEESQRKLQVV 397
Query: 452 RDKLIHCINLNRTYRET-YIFVKNHPFLPNTEQFSFSENYVFGKFDTFCKRLNKIIAMFD 510
D L + RE + + K + +++ F + VF + D F RL+ + +
Sbjct: 398 SDTLSFFKQEFQDRRENLHTYFKEN---QEVKEWDFQSSLVFVRLDGFLGRLHVVEGLLK 454
Query: 511 LTDDYNYLFEKRMXXXXXXXXXXXA--VH-TFEEAKKAVTTCQYDYLDYRNNEFDKDYHA 567
D++ L + +H F+E + ++ D L ++ +F+ D
Sbjct: 455 TALDFHKLGKVEFSGVRGNALSQQVQQMHEEFQEMYRLLSGSSSDCLYLQSTDFENDVSE 514
Query: 568 FEDKINALKESIGCTIEENFSSVWETPQGIKFL 600
F K+ L +G + F K L
Sbjct: 515 FNQKVEDLDRRLGTIFIQAFDDAPGLEHAFKLL 547
Score = 38.7 bits (86), Expect = 0.10
Identities = 33/179 (18%), Positives = 74/179 (41%), Gaps = 5/179 (2%)
Query: 638 HPVLRGLPASADMMRKYTNTRTLMNNYEDMMKAVWMNQNLWDVDESLNNSLLKID-ETGC 696
HP + M +KY + +L+ YE + W +L+ LLK D ET
Sbjct: 633 HPCMESAEGKR-MQQKYEDMLSLLEKYETRLYEDWCRTVSEKSQYNLSQPLLKRDPETKE 691
Query: 697 VAVNLDKNIKLLIRESDCLVKMGVP-LPIVCHSLYAKKYYFTLVNDSLQFLLEDYLRTVR 755
+ +N + + +++E L + +P ++++ + ++ + +L+ L+ ++ V
Sbjct: 692 ITINFNPQLISVLKEMSYLEPREMKHMPETAAAMFSSRDFYRQLVANLE-LMANWYNKVM 750
Query: 756 RVKLEVR-PLFLPQXXXXXXXXXXXXXXXCWTSEGWKEFIDRANAAIKSFDVLVTRVHD 813
+ LEV PL + W +EG +++ ++I + + + D
Sbjct: 751 KTLLEVEFPLVEEELQNIDLRLRAAEETLNWKTEGICDYVTEITSSIHDLEQRIQKTKD 809
>BC112284-1|AAI12285.1| 566|Homo sapiens dynein, axonemal, heavy
chain like 1 protein.
Length = 566
Score = 58.8 bits (136), Expect = 9e-08
Identities = 46/202 (22%), Positives = 86/202 (42%), Gaps = 7/202 (3%)
Query: 393 ILSLLQTVRLIHSVSQFYNTSERISSLMVKITNQMIETCKQYITCRFKDTIWSQERSLVR 452
I +L T+ I + S++YNT RI ++ + NQ+IE + +++ E V
Sbjct: 13 IAKVLDTICFIWATSEYYNTPARIIVILQEFCNQIIEMTRTFLSPEEVLKGLQGEIEEVL 72
Query: 453 DKLIHCINLNRTYRETYIF--VKNHPFLPNTEQ--FSFSENYVFGKFDTFCKRLNKIIAM 508
+ +N+ + +TY F V F + E + F + F + ++F +R+ I +
Sbjct: 73 SGISLAVNVLKELYQTYDFCCVNMKLFFKDKEPVPWEFPSSLAFSRINSFFQRIQTIEEL 132
Query: 509 FDLTDDYNYLFEKRMXXXXXXXXXXXAVHTFEEA---KKAVTTCQYDYLDYRNNEFDKDY 565
+ ++ L + + ++E K C+YD LD ++ FD+DY
Sbjct: 133 YKTAIEFLKLEKIELGGVRGNLLGSLVTRIYDEVFELVKVFADCKYDPLDPGDSNFDRDY 192
Query: 566 HAFEDKINALKESIGCTIEENF 587
FE KI L + + F
Sbjct: 193 ADFEIKIQDLDRRLATIFCQGF 214
>BC105107-1|AAI05108.1| 566|Homo sapiens dynein, axonemal, heavy
chain like 1 protein.
Length = 566
Score = 58.8 bits (136), Expect = 9e-08
Identities = 46/202 (22%), Positives = 86/202 (42%), Gaps = 7/202 (3%)
Query: 393 ILSLLQTVRLIHSVSQFYNTSERISSLMVKITNQMIETCKQYITCRFKDTIWSQERSLVR 452
I +L T+ I + S++YNT RI ++ + NQ+IE + +++ E V
Sbjct: 13 IAKVLDTICFIWATSEYYNTPARIIVILQEFCNQIIEMTRTFLSPEEVLKGLQGEIEEVL 72
Query: 453 DKLIHCINLNRTYRETYIF--VKNHPFLPNTEQ--FSFSENYVFGKFDTFCKRLNKIIAM 508
+ +N+ + +TY F V F + E + F + F + ++F +R+ I +
Sbjct: 73 SGISLAVNVLKELYQTYDFCCVNMKLFFKDKEPVPWEFPSSLAFSRINSFFQRIQTIEEL 132
Query: 509 FDLTDDYNYLFEKRMXXXXXXXXXXXAVHTFEEA---KKAVTTCQYDYLDYRNNEFDKDY 565
+ ++ L + + ++E K C+YD LD ++ FD+DY
Sbjct: 133 YKTAIEFLKLEKIELGGVRGNLLGSLVTRIYDEVFELVKVFADCKYDPLDPGDSNFDRDY 192
Query: 566 HAFEDKINALKESIGCTIEENF 587
FE KI L + + F
Sbjct: 193 ADFEIKIQDLDRRLATIFCQGF 214
>AK097776-1|BAC05170.1| 566|Homo sapiens protein ( Homo sapiens
cDNA FLJ40457 fis, clone TESTI2041730, weakly similar to
DYNEIN BETA CHAIN, CILIARY. ).
Length = 566
Score = 58.8 bits (136), Expect = 9e-08
Identities = 46/202 (22%), Positives = 86/202 (42%), Gaps = 7/202 (3%)
Query: 393 ILSLLQTVRLIHSVSQFYNTSERISSLMVKITNQMIETCKQYITCRFKDTIWSQERSLVR 452
I +L T+ I + S++YNT RI ++ + NQ+IE + +++ E V
Sbjct: 13 IAKVLDTICFIWATSEYYNTPARIIVILQEFCNQIIEMTRTFLSPEEVLKGLQGEIEEVL 72
Query: 453 DKLIHCINLNRTYRETYIF--VKNHPFLPNTEQ--FSFSENYVFGKFDTFCKRLNKIIAM 508
+ +N+ + +TY F V F + E + F + F + ++F +R+ I +
Sbjct: 73 SGISLAVNVLKELYQTYDFCCVNMKLFFKDKEPVPWEFPSSLAFSRINSFFQRIQTIEEL 132
Query: 509 FDLTDDYNYLFEKRMXXXXXXXXXXXAVHTFEEA---KKAVTTCQYDYLDYRNNEFDKDY 565
+ ++ L + + ++E K C+YD LD ++ FD+DY
Sbjct: 133 YKTAIEFLKLEKIELGGVRGNLLGSLVTRIYDEVFELVKVFADCKYDPLDPGDSNFDRDY 192
Query: 566 HAFEDKINALKESIGCTIEENF 587
FE KI L + + F
Sbjct: 193 ADFEIKIQDLDRRLATIFCQGF 214
>AB040936-1|BAA96027.2| 4464|Homo sapiens KIAA1503 protein protein.
Length = 4464
Score = 57.6 bits (133), Expect = 2e-07
Identities = 36/135 (26%), Positives = 64/135 (47%), Gaps = 1/135 (0%)
Query: 289 QILSESEQLRREVDSSGPQDELEYWKKRGAQFSQLVSYLQENEVQLTLSCLQLANSKVIK 348
++LS E + ++ GP +E+E+W+ R S + L + V+ S L LA S +
Sbjct: 295 EMLSAQETVETG-ENLGPLEEIEFWRNRCMDLSGISKQLVKKGVKHVESILHLAKSSYLA 353
Query: 349 QWRDTDHKITFCYNEAKDNAKFVQAMEKCCHSLYLDDPVKIKDSILSLLQTVRLIHSVSQ 408
+ +I +A+ N F+ +++ L P I + L+ +R+I S
Sbjct: 354 PFMKLAQQIQDGSRQAQSNLTFLSILKEPYQELAFMKPKDISSKLPKLISLIRIIWVNSP 413
Query: 409 FYNTSERISSLMVKI 423
YNT ER++SL K+
Sbjct: 414 HYNTRERLTSLFRKV 428
>Y10601-1|CAA71610.1| 1119|Homo sapiens ankyrin-like protein protein.
Length = 1119
Score = 37.9 bits (84), Expect = 0.18
Identities = 37/167 (22%), Positives = 78/167 (46%), Gaps = 13/167 (7%)
Query: 202 PIVKNQLLPGLRSFCSALKVCEDVCNQVNLFEDGLAL--MAPIQDHTQLKDMAKNPNTIT 259
P ++N+L + SF + V + GLA+ +A +Q H LK +A T
Sbjct: 925 PYLRNELAHPVLSFAQLVSFTIFVPIVLMNLLIGLAVGDIAEVQKHASLKRIAMQVELHT 984
Query: 260 MLEERVTEWIKKVMEVASLLIFPNHAFNDQILSE-------SEQLRREVDSSGPQDELEY 312
LE+++ W + ++ S +++PN + +L + ++R+E+ ++ E+E
Sbjct: 985 SLEKKLPLWFLRKVDQKSTIVYPNKPRSGGMLFHIFCFLFCTGEIRQEIPNADKSLEMEI 1044
Query: 313 WKKRGAQFSQLVSYLQENEVQLTLSCLQLANSKVIKQWRDTDHKITF 359
K++ + L ++L E + +L +Q ++I + D D +F
Sbjct: 1045 LKQK-YRLKDL-TFLLEKQHELIKLIIQ--KMEIISETEDDDSHCSF 1087
>BC118914-1|AAI18915.1| 915|Homo sapiens oxysterol binding protein
2 protein.
Length = 915
Score = 32.7 bits (71), Expect = 6.8
Identities = 24/96 (25%), Positives = 45/96 (46%), Gaps = 4/96 (4%)
Query: 172 VTAIERVMEHVYMSALAHPSSDGDEDETRFPIVKNQLLPGLRSFCSALKVCE-DVCNQVN 230
+TA+E H GD+DE P K++L L++ +LK+ + CN +
Sbjct: 266 ITALELAKAKAVRVMNTHSDDSGDDDEATTPADKSELHHTLKNL--SLKLDDLSTCNDL- 322
Query: 231 LFEDGLALMAPIQDHTQLKDMAKNPNTITMLEERVT 266
+ + G AL + + LK +++ + ++ ER T
Sbjct: 323 IAKHGAALQRSLTELDGLKIPSESGEKLKVVNERAT 358
>BC064370-1|AAH64370.1| 2335|Homo sapiens PRP8 pre-mRNA processing
factor 8 homolog (S. cerevisiae) protein.
Length = 2335
Score = 32.7 bits (71), Expect = 6.8
Identities = 16/41 (39%), Positives = 23/41 (56%), Gaps = 3/41 (7%)
Query: 581 CTIEENFSSVWETPQG---IKFLTRFEKVSQKIQITKLRRI 618
C N VWET +G + +RFEK+ +KI +T L R+
Sbjct: 956 CQGINNLQDVWETSEGECNVMLESRFEKMYEKIDLTLLNRL 996
>AL079299-1|CAI14632.1| 917|Homo sapiens oxysterol binding protein
2 protein.
Length = 917
Score = 32.7 bits (71), Expect = 6.8
Identities = 24/96 (25%), Positives = 45/96 (46%), Gaps = 4/96 (4%)
Query: 172 VTAIERVMEHVYMSALAHPSSDGDEDETRFPIVKNQLLPGLRSFCSALKVCE-DVCNQVN 230
+TA+E H GD+DE P K++L L++ +LK+ + CN +
Sbjct: 266 ITALELAKAKAVRVMNTHSDDSGDDDEATTPADKSELHHTLKNL--SLKLDDLSTCNDL- 322
Query: 231 LFEDGLALMAPIQDHTQLKDMAKNPNTITMLEERVT 266
+ + G AL + + LK +++ + ++ ER T
Sbjct: 323 IAKHGAALQRSLTELDGLKIPSESGEKLKVVNERAT 358
>AL022336-1|CAI22805.1| 917|Homo sapiens oxysterol binding protein
2 protein.
Length = 917
Score = 32.7 bits (71), Expect = 6.8
Identities = 24/96 (25%), Positives = 45/96 (46%), Gaps = 4/96 (4%)
Query: 172 VTAIERVMEHVYMSALAHPSSDGDEDETRFPIVKNQLLPGLRSFCSALKVCE-DVCNQVN 230
+TA+E H GD+DE P K++L L++ +LK+ + CN +
Sbjct: 266 ITALELAKAKAVRVMNTHSDDSGDDDEATTPADKSELHHTLKNL--SLKLDDLSTCNDL- 322
Query: 231 LFEDGLALMAPIQDHTQLKDMAKNPNTITMLEERVT 266
+ + G AL + + LK +++ + ++ ER T
Sbjct: 323 IAKHGAALQRSLTELDGLKIPSESGEKLKVVNERAT 358
>AK131374-1|BAD18525.1| 743|Homo sapiens protein ( Homo sapiens
cDNA FLJ16431 fis, clone BRACE3009127, highly similar
to Homo sapiens oxysterol binding protein 2 (OSBP2). ).
Length = 743
Score = 32.7 bits (71), Expect = 6.8
Identities = 24/96 (25%), Positives = 45/96 (46%), Gaps = 4/96 (4%)
Query: 172 VTAIERVMEHVYMSALAHPSSDGDEDETRFPIVKNQLLPGLRSFCSALKVCE-DVCNQVN 230
+TA+E H GD+DE P K++L L++ +LK+ + CN +
Sbjct: 93 ITALELAKAKAVRVMNTHSDDSGDDDEATTPADKSELHHTLKNL--SLKLDDLSTCNDL- 149
Query: 231 LFEDGLALMAPIQDHTQLKDMAKNPNTITMLEERVT 266
+ + G AL + + LK +++ + ++ ER T
Sbjct: 150 IAKHGAALQRSLTELDGLKIPSESGEKLKVVNERAT 185
>AF323731-1|AAG53406.1| 916|Homo sapiens OSBP-related protein 4
protein.
Length = 916
Score = 32.7 bits (71), Expect = 6.8
Identities = 24/96 (25%), Positives = 45/96 (46%), Gaps = 4/96 (4%)
Query: 172 VTAIERVMEHVYMSALAHPSSDGDEDETRFPIVKNQLLPGLRSFCSALKVCE-DVCNQVN 230
+TA+E H GD+DE P K++L L++ +LK+ + CN +
Sbjct: 266 ITALELAKAKAVRVMNTHSDDSGDDDEATTPADKSELHHTLKNL--SLKLDDLSTCNDL- 322
Query: 231 LFEDGLALMAPIQDHTQLKDMAKNPNTITMLEERVT 266
+ + G AL + + LK +++ + ++ ER T
Sbjct: 323 IAKHGAALQRSLTELDGLKIPSESGEKLKVVNERAT 358
>AF288742-1|AAK56865.1| 878|Homo sapiens oxysterol binding protein
2 protein.
Length = 878
Score = 32.7 bits (71), Expect = 6.8
Identities = 24/96 (25%), Positives = 45/96 (46%), Gaps = 4/96 (4%)
Query: 172 VTAIERVMEHVYMSALAHPSSDGDEDETRFPIVKNQLLPGLRSFCSALKVCE-DVCNQVN 230
+TA+E H GD+DE P K++L L++ +LK+ + CN +
Sbjct: 228 ITALELAKAKAVRVMNTHSDDSGDDDEATTPADKSELHHTLKNL--SLKLDDLSTCNDL- 284
Query: 231 LFEDGLALMAPIQDHTQLKDMAKNPNTITMLEERVT 266
+ + G AL + + LK +++ + ++ ER T
Sbjct: 285 IAKHGAALQRSLTELDGLKIPSESGEKLKVVNERAT 320
>AF288741-1|AAK56864.1| 878|Homo sapiens oxysterol binding protein
2 protein.
Length = 878
Score = 32.7 bits (71), Expect = 6.8
Identities = 24/96 (25%), Positives = 45/96 (46%), Gaps = 4/96 (4%)
Query: 172 VTAIERVMEHVYMSALAHPSSDGDEDETRFPIVKNQLLPGLRSFCSALKVCE-DVCNQVN 230
+TA+E H GD+DE P K++L L++ +LK+ + CN +
Sbjct: 228 ITALELAKAKAVRVMNTHSDDSGDDDEATTPADKSELHHTLKNL--SLKLDDLSTCNDL- 284
Query: 231 LFEDGLALMAPIQDHTQLKDMAKNPNTITMLEERVT 266
+ + G AL + + LK +++ + ++ ER T
Sbjct: 285 IAKHGAALQRSLTELDGLKIPSESGEKLKVVNERAT 320
>AF092565-1|AAC61776.1| 2335|Homo sapiens splicing factor Prp8
protein.
Length = 2335
Score = 32.7 bits (71), Expect = 6.8
Identities = 16/41 (39%), Positives = 23/41 (56%), Gaps = 3/41 (7%)
Query: 581 CTIEENFSSVWETPQG---IKFLTRFEKVSQKIQITKLRRI 618
C N VWET +G + +RFEK+ +KI +T L R+
Sbjct: 956 CQGINNLQDVWETSEGECNVMLESRFEKMYEKIDLTLLNRL 996
>AB051451-1|BAB33334.2| 920|Homo sapiens KIAA1664 protein protein.
Length = 920
Score = 32.7 bits (71), Expect = 6.8
Identities = 24/96 (25%), Positives = 45/96 (46%), Gaps = 4/96 (4%)
Query: 172 VTAIERVMEHVYMSALAHPSSDGDEDETRFPIVKNQLLPGLRSFCSALKVCE-DVCNQVN 230
+TA+E H GD+DE P K++L L++ +LK+ + CN +
Sbjct: 270 ITALELAKAKAVRVMNTHSDDSGDDDEATTPADKSELHHTLKNL--SLKLDDLSTCNDL- 326
Query: 231 LFEDGLALMAPIQDHTQLKDMAKNPNTITMLEERVT 266
+ + G AL + + LK +++ + ++ ER T
Sbjct: 327 IAKHGAALQRSLTELDGLKIPSESGEKLKVVNERAT 362
>AB007510-1|BAA22563.1| 2335|Homo sapiens PRP8 protein protein.
Length = 2335
Score = 32.7 bits (71), Expect = 6.8
Identities = 16/41 (39%), Positives = 23/41 (56%), Gaps = 3/41 (7%)
Query: 581 CTIEENFSSVWETPQG---IKFLTRFEKVSQKIQITKLRRI 618
C N VWET +G + +RFEK+ +KI +T L R+
Sbjct: 956 CQGINNLQDVWETSEGECNVMLESRFEKMYEKIDLTLLNRL 996
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.321 0.135 0.404
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 134,813,325
Number of Sequences: 224733
Number of extensions: 5315671
Number of successful extensions: 12111
Number of sequences better than 10.0: 38
Number of HSP's better than 10.0 without gapping: 27
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 11932
Number of HSP's gapped (non-prelim): 105
length of query: 1013
length of database: 73,234,838
effective HSP length: 97
effective length of query: 916
effective length of database: 51,435,737
effective search space: 47115135092
effective search space used: 47115135092
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.9 bits)
S2: 70 (32.3 bits)
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