Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA002140-TA|BGIBMGA002140-PA|IPR000873|AMP-dependent
synthetase and ligase
(1071 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI00015B6235 Cluster: PREDICTED: similar to ENSANGP000... 1755 0.0
UniRef50_Q9W0S9 Cluster: Disco-interacting protein 2; n=16; Eume... 1536 0.0
UniRef50_Q14689 Cluster: Disco-interacting protein 2 homolog A; ... 1299 0.0
UniRef50_Q4SKU1 Cluster: Chromosome undetermined SCAF14565, whol... 1125 0.0
UniRef50_Q1RS87 Cluster: Putative uncharacterized protein; n=2; ... 1070 0.0
UniRef50_Q4RQQ3 Cluster: Chromosome 2 SCAF15004, whole genome sh... 694 0.0
UniRef50_Q4SU65 Cluster: Chromosome undetermined SCAF14007, whol... 592 e-167
UniRef50_Q86XV3 Cluster: DIP2C protein; n=2; Euteleostomi|Rep: D... 543 e-153
UniRef50_Q4T6E9 Cluster: Chromosome undetermined SCAF8797, whole... 530 e-149
UniRef50_UPI0000F1EC39 Cluster: PREDICTED: similar to KIAA0184 p... 431 e-119
UniRef50_Q4SL77 Cluster: Chromosome undetermined SCAF14561, whol... 330 1e-88
UniRef50_Q4SNK5 Cluster: Chromosome 15 SCAF14542, whole genome s... 247 1e-63
UniRef50_Q4RQ07 Cluster: Chromosome 17 SCAF15006, whole genome s... 229 2e-58
UniRef50_UPI0001556409 Cluster: PREDICTED: similar to mKIAA1463 ... 197 2e-48
UniRef50_Q5A8P6 Cluster: Acyl CoA ligase-like protein; n=6; Sacc... 186 4e-45
UniRef50_A6QYH2 Cluster: Putative uncharacterized protein; n=1; ... 182 4e-44
UniRef50_A1D1R6 Cluster: AMP binding domain protein, putative; n... 179 4e-43
UniRef50_Q10250 Cluster: Uncharacterized protein C56F8.02; n=1; ... 175 4e-42
UniRef50_Q4SNK2 Cluster: Chromosome 15 SCAF14542, whole genome s... 175 7e-42
UniRef50_Q6CA71 Cluster: Similar to tr|Q9C3Z2 Cochliobolus heter... 173 2e-41
UniRef50_Q2UQJ0 Cluster: Predicted AMP-binding protein; n=6; Pez... 173 3e-41
UniRef50_Q5YZV8 Cluster: Putative acyl-CoA synthetase; n=1; Noca... 167 1e-39
UniRef50_Q1D6A2 Cluster: Non-ribosomal peptide synthase; n=1; My... 164 1e-38
UniRef50_Q096N9 Cluster: Beta-ketoacyl synthase; n=1; Stigmatell... 159 3e-37
UniRef50_A3ILP8 Cluster: Beta-ketoacyl synthase; n=1; Cyanothece... 158 7e-37
UniRef50_Q1D5W2 Cluster: Non-ribosomal peptide synthetase/polyke... 158 9e-37
UniRef50_Q08XI8 Cluster: Beta-lactamase, putative; n=3; Bacteria... 157 1e-36
UniRef50_Q2SHY7 Cluster: Polyketide synthase modules and related... 157 2e-36
UniRef50_Q7RZX2 Cluster: Putative uncharacterized protein NCU002... 157 2e-36
UniRef50_Q1D438 Cluster: Non-ribosomal peptide synthase; n=8; Ba... 154 1e-35
UniRef50_Q3M1P5 Cluster: Amino acid adenylation; n=2; Cyanobacte... 150 2e-34
UniRef50_Q09E86 Cluster: AMP-binding enzyme domain protein; n=1;... 146 3e-33
UniRef50_Q8YPY3 Cluster: Alr4057 protein; n=5; Cyanobacteria|Rep... 146 4e-33
UniRef50_Q0B3F8 Cluster: AMP-dependent synthetase and ligase; n=... 145 7e-33
UniRef50_Q3M5M8 Cluster: Beta-ketoacyl synthase; n=4; Bacteria|R... 144 1e-32
UniRef50_UPI000045BBBF Cluster: COG0318: Acyl-CoA synthetases (A... 141 8e-32
UniRef50_Q4SNK4 Cluster: Chromosome 15 SCAF14542, whole genome s... 140 2e-31
UniRef50_A5IE32 Cluster: Saframycin Mx1 synthetase B; n=4; Legio... 140 2e-31
UniRef50_Q113H9 Cluster: AMP-dependent synthetase and ligase; n=... 137 2e-30
UniRef50_A3IW78 Cluster: Beta-ketoacyl synthase; n=2; Cyanobacte... 135 5e-30
UniRef50_Q2T3X5 Cluster: AMP-binding domain protein; n=10; pseud... 133 2e-29
UniRef50_Q7NJ79 Cluster: Gll1953 protein; n=1; Gloeobacter viola... 133 3e-29
UniRef50_A0PMY3 Cluster: Fatty-acid-CoA ligase; n=1; Mycobacteri... 133 3e-29
UniRef50_UPI000038D260 Cluster: COG1020: Non-ribosomal peptide s... 132 4e-29
UniRef50_Q7B6G6 Cluster: Peptide synthetase NRPS5-4-3; n=2; Stre... 132 4e-29
UniRef50_Q0B1F1 Cluster: Beta-ketoacyl synthase; n=1; Burkholder... 132 4e-29
UniRef50_Q4KK26 Cluster: Pyoverdine synthetase; n=1; Pseudomonas... 132 5e-29
UniRef50_Q21HW6 Cluster: AMP-dependent synthetase and ligase; n=... 132 5e-29
UniRef50_A6GHN6 Cluster: Non-ribosomal peptide synthase; n=1; Pl... 132 5e-29
UniRef50_Q1D3K4 Cluster: Non-ribosomal peptide synthase; n=2; My... 129 3e-28
UniRef50_Q08U40 Cluster: Beta-ketoacyl synthase; n=1; Stigmatell... 129 3e-28
UniRef50_Q21WI4 Cluster: AMP-dependent synthetase and ligase; n=... 125 6e-27
UniRef50_Q1D591 Cluster: Nonribosomal peptide synthetase; n=1; M... 125 7e-27
UniRef50_Q0LP47 Cluster: AMP-dependent synthetase and ligase; n=... 124 1e-26
UniRef50_O54155 Cluster: Polyketide synthase; n=2; Actinomycetal... 124 1e-26
UniRef50_Q50857 Cluster: Saframycin Mx1 synthetase B; n=1; Myxoc... 124 1e-26
UniRef50_Q090E5 Cluster: Beta-ketoacyl synthase; n=1; Stigmatell... 123 2e-26
UniRef50_UPI000038CE97 Cluster: COG0318: Acyl-CoA synthetases (A... 123 3e-26
UniRef50_Q1D3S3 Cluster: Non-ribosomal peptide synthase; n=3; Ba... 123 3e-26
UniRef50_A4YZI2 Cluster: Putative fatty-acid--CoA ligase; n=1; B... 122 7e-26
UniRef50_Q094Z1 Cluster: Beta-ketoacyl synthase; n=1; Stigmatell... 121 9e-26
UniRef50_Q87WM8 Cluster: Non-ribosomal peptide synthetase, initi... 120 2e-25
UniRef50_Q2JCL4 Cluster: AMP-dependent synthetase and ligase; n=... 120 3e-25
UniRef50_A3RTM9 Cluster: Putative uncharacterized protein; n=1; ... 120 3e-25
UniRef50_Q7UYT8 Cluster: Saframycin Mx1 synthetase B; n=2; Bacte... 118 9e-25
UniRef50_Q3JS97 Cluster: Unnamed protein product; n=10; Burkhold... 118 9e-25
UniRef50_A3YGJ3 Cluster: Beta-ketoacyl synthase; n=1; Marinomona... 118 1e-24
UniRef50_Q7NJ84 Cluster: Gll1948 protein; n=21; Bacteria|Rep: Gl... 116 3e-24
UniRef50_Q7UWD6 Cluster: Acyl-CoA synthetase; n=1; Pirellula sp.... 116 3e-24
UniRef50_A3ZQ92 Cluster: Saframycin Mx1 synthetase B; n=1; Blast... 116 3e-24
UniRef50_Q73UT2 Cluster: FadD29; n=2; Mycobacterium avium|Rep: F... 115 8e-24
UniRef50_Q5C1Y4 Cluster: SJCHGC08625 protein; n=1; Schistosoma j... 114 1e-23
UniRef50_Q1I2J3 Cluster: Putative polyketide synthase; putative ... 112 4e-23
UniRef50_A5B1G8 Cluster: Putative uncharacterized protein; n=2; ... 112 4e-23
UniRef50_Q2T6Q9 Cluster: AMP-binding domain protein; n=1; Burkho... 112 6e-23
UniRef50_Q62C92 Cluster: AMP-binding domain protein; n=17; Bacte... 111 1e-22
UniRef50_A4XWA9 Cluster: Amino acid adenylation domain; n=1; Pse... 111 1e-22
UniRef50_Q01KB0 Cluster: OSIGBa0135C13.1 protein; n=3; Oryza sat... 109 3e-22
UniRef50_Q8GGQ3 Cluster: Nonribosomal peptide synthetase; n=2; S... 108 7e-22
UniRef50_Q0LN70 Cluster: Amino acid adenylation; n=1; Herpetosip... 108 7e-22
UniRef50_Q211N2 Cluster: AMP-dependent synthetase and ligase pre... 108 9e-22
UniRef50_UPI000011F913 Cluster: UPI000011F913 related cluster; n... 107 1e-21
UniRef50_Q9FB23 Cluster: Peptide synthetase NRPS5-4-3; n=1; Stre... 107 1e-21
UniRef50_A1T3T7 Cluster: AMP-dependent synthetase and ligase; n=... 107 1e-21
UniRef50_A1WM65 Cluster: AMP-dependent synthetase and ligase; n=... 107 2e-21
UniRef50_A0FRX9 Cluster: AMP-dependent synthetase and ligase; n=... 106 3e-21
UniRef50_Q9I157 Cluster: PvdL; n=23; root|Rep: PvdL - Pseudomona... 105 5e-21
UniRef50_Q212V5 Cluster: Amino acid adenylation; n=2; cellular o... 105 6e-21
UniRef50_Q2T8M1 Cluster: AMP-binding domain protein; n=7; pseudo... 105 9e-21
UniRef50_Q93HG9 Cluster: Non-ribosomal peptide synthetase; n=1; ... 104 1e-20
UniRef50_A7Q867 Cluster: Chromosome undetermined scaffold_62, wh... 103 2e-20
UniRef50_A6FHW6 Cluster: Amino acid adenylation; n=1; Moritella ... 103 3e-20
UniRef50_A4C5W5 Cluster: Beta-ketoacyl synthase; n=1; Pseudoalte... 103 3e-20
UniRef50_A6P633 Cluster: Acyl-ACP synthetase; n=1; Microcystis a... 103 3e-20
UniRef50_A3ZWL3 Cluster: Saframycin Mx1 synthetase B; n=1; Blast... 103 3e-20
UniRef50_A6G174 Cluster: Non-ribosomal peptide synthase; n=1; Pl... 102 6e-20
UniRef50_Q11ZV6 Cluster: AMP-dependent synthetase and ligase; n=... 101 1e-19
UniRef50_Q4BZ64 Cluster: AMP-dependent synthetase and ligase; n=... 100 2e-19
UniRef50_A6E0C1 Cluster: Non-ribosomal peptide synthase; n=1; Ro... 100 2e-19
UniRef50_A1YBQ9 Cluster: AmbG; n=1; Sorangium cellulosum|Rep: Am... 100 2e-19
UniRef50_A5NTM2 Cluster: AMP-dependent synthetase and ligase; n=... 99 3e-19
UniRef50_Q8YTN6 Cluster: Alr2678 protein; n=2; Nostocaceae|Rep: ... 99 7e-19
UniRef50_Q3JM63 Cluster: Peptide synthetase NRPS5-4-3; n=16; Bur... 98 1e-18
UniRef50_Q7CT18 Cluster: AGR_L_2326p; n=2; Agrobacterium tumefac... 94 2e-17
UniRef50_Q7D7S1 Cluster: Acyl-CoA synthase; n=15; Mycobacterium|... 94 2e-17
UniRef50_A7NZW0 Cluster: Chromosome chr6 scaffold_3, whole genom... 93 4e-17
UniRef50_Q8XYF2 Cluster: Probable polyketide synthase protein; n... 92 6e-17
UniRef50_A4ZPY1 Cluster: DepA; n=2; Betaproteobacteria|Rep: DepA... 92 8e-17
UniRef50_A4KUB2 Cluster: TlmVI; n=1; Streptoalloteichus hindusta... 91 1e-16
UniRef50_A4JL36 Cluster: AMP-dependent synthetase and ligase; n=... 91 1e-16
UniRef50_Q8NLR6 Cluster: Acyl-CoA synthetases (AMP-forming)/AMP-... 91 2e-16
UniRef50_Q7X541 Cluster: Acyl-CoA synthase; n=1; Actinoplanes fr... 91 2e-16
UniRef50_A0G714 Cluster: AMP-dependent synthetase and ligase; n=... 89 8e-16
UniRef50_Q0LNS7 Cluster: Amino acid adenylation; n=1; Herpetosip... 88 1e-15
UniRef50_Q45R86 Cluster: Acyl-CoA ligase; n=2; Streptomyces|Rep:... 87 2e-15
UniRef50_Q09773 Cluster: Meiotically up-regulated gene 62 protei... 87 3e-15
UniRef50_Q2RPP1 Cluster: Aspartate racemase; n=1; Rhodospirillum... 86 4e-15
UniRef50_Q4C7P5 Cluster: AMP-dependent synthetase and ligase:Acy... 86 4e-15
UniRef50_A5NY43 Cluster: AMP-dependent synthetase and ligase; n=... 86 4e-15
UniRef50_Q2Y7Z2 Cluster: Amino acid adenylation; n=1; Nitrosospi... 85 7e-15
UniRef50_Q10976 Cluster: Putative fatty-acid--CoA ligase fadD26;... 85 7e-15
UniRef50_Q1ITR1 Cluster: AMP-dependent synthetase and ligase; n=... 84 2e-14
UniRef50_Q62B68 Cluster: AMP-binding domain protein; n=11; Burkh... 83 4e-14
UniRef50_Q5VNP6 Cluster: Acyl-CoA ligase-like; n=4; Oryza sativa... 82 7e-14
UniRef50_A7HI15 Cluster: AMP-dependent synthetase and ligase; n=... 81 2e-13
UniRef50_A4KE92 Cluster: Fatty-acid-CoA ligase fadD30; n=6; Myco... 81 2e-13
UniRef50_Q82U49 Cluster: AMP-dependent synthetase and ligase; n=... 80 3e-13
UniRef50_Q0V137 Cluster: Putative uncharacterized protein; n=1; ... 80 4e-13
UniRef50_Q93GZ6 Cluster: Non-ribosomal peptide synthetase; n=1; ... 79 5e-13
UniRef50_Q70AY2 Cluster: Acyl-CoA ligase; n=2; Actinoplanes teic... 79 6e-13
UniRef50_A0V6T7 Cluster: Amino acid adenylation domain; n=2; Com... 79 8e-13
UniRef50_Q0S9C5 Cluster: Fatty-acid--CoA ligase; n=27; Corynebac... 78 1e-12
UniRef50_A3RUE6 Cluster: Putative uncharacterized protein; n=1; ... 77 3e-12
UniRef50_Q12275 Cluster: Uncharacterized protein YOR093C; n=3; S... 77 3e-12
UniRef50_Q0M3P0 Cluster: AMP-dependent synthetase and ligase; n=... 76 6e-12
UniRef50_Q83EJ6 Cluster: AMP-binding enzyme family protein; n=2;... 75 8e-12
UniRef50_A2WSZ9 Cluster: Putative uncharacterized protein; n=1; ... 75 1e-11
UniRef50_UPI0000F2C3ED Cluster: PREDICTED: similar to mKIAA1611 ... 74 2e-11
UniRef50_Q127J0 Cluster: AMP-dependent synthetase and ligase; n=... 74 2e-11
UniRef50_Q8XRP4 Cluster: Putative amp-dependent synthetase and l... 73 3e-11
UniRef50_A4F3K2 Cluster: Non-ribosomal peptide synthetase/polyke... 72 7e-11
UniRef50_Q5P000 Cluster: CoA ligase, AMP generating; n=2; Betapr... 71 2e-10
UniRef50_Q1MX62 Cluster: Putative acyltransferase family protein... 71 2e-10
UniRef50_A3WXS1 Cluster: Probable non-ribosomal peptide syntheta... 71 2e-10
UniRef50_A7TLF5 Cluster: Putative uncharacterized protein; n=1; ... 70 3e-10
UniRef50_A7IJ33 Cluster: Amino acid adenylation domain; n=1; Xan... 70 4e-10
UniRef50_Q70C47 Cluster: Polyketide non-ribosomal peptide syntha... 67 3e-09
UniRef50_A4BLA6 Cluster: Hypothetical acyltransferase family pro... 65 1e-08
UniRef50_A1WAC8 Cluster: AMP-dependent synthetase and ligase; n=... 65 1e-08
UniRef50_Q96VP8 Cluster: Putative fatty acid CoA ligase; n=1; Gl... 64 2e-08
UniRef50_P27206 Cluster: Surfactin synthetase subunit 1; n=15; B... 64 3e-08
UniRef50_P72116 Cluster: PAO substrain OT684 pyoverdine gene tra... 63 3e-08
UniRef50_Q06YY4 Cluster: Acyl-CoA ligase/dehydrogenase fusion pr... 63 4e-08
UniRef50_A1WAC9 Cluster: AMP-dependent synthetase and ligase; n=... 62 1e-07
UniRef50_A3IZB3 Cluster: Amino acid adenylation; n=2; Chroococca... 61 1e-07
UniRef50_Q1RS73 Cluster: NRPS/PKS protein; n=5; Bacteria|Rep: NR... 61 2e-07
UniRef50_Q83AH1 Cluster: Acyltransferase family protein; n=4; Co... 60 3e-07
UniRef50_A7IE19 Cluster: AMP-dependent synthetase and ligase; n=... 60 4e-07
UniRef50_A7GTF8 Cluster: Beta-ketoacyl synthase; n=3; cellular o... 59 6e-07
UniRef50_Q5CUM8 Cluster: Type I fatty acid synthase; n=4; Crypto... 59 7e-07
UniRef50_Q9A929 Cluster: Acyl-CoA synthetase; n=4; Alphaproteoba... 58 1e-06
UniRef50_Q1JTE1 Cluster: Type I fatty acid synthase, putative; n... 58 1e-06
UniRef50_Q0C1U0 Cluster: Putative AMP binding protein; n=1; Hyph... 58 1e-06
UniRef50_Q666G1 Cluster: Possible high molecular weight sideroph... 58 2e-06
UniRef50_A0UXD2 Cluster: Amino acid adenylation domain; n=1; Clo... 58 2e-06
UniRef50_Q47NS0 Cluster: Amino acid adenylation; n=1; Thermobifi... 57 2e-06
UniRef50_Q6Q883 Cluster: SirP; n=2; Ascomycota|Rep: SirP - Lepto... 57 2e-06
UniRef50_A2QYX4 Cluster: Contig An12c0080, complete genome; n=1;... 56 4e-06
UniRef50_O94116 Cluster: Peptide synthetase; n=1; Aureobasidium ... 56 5e-06
UniRef50_Q9LCU0 Cluster: PstD; n=2; Mycobacterium avium|Rep: Pst... 56 7e-06
UniRef50_Q197G2 Cluster: Nonribosomal peptide synthetase; n=2; S... 56 7e-06
UniRef50_A4D936 Cluster: CrpD; n=2; Nostocaceae|Rep: CrpD - Nost... 56 7e-06
UniRef50_Q04747 Cluster: Surfactin synthetase subunit 2; n=9; Ba... 56 7e-06
UniRef50_Q70LM5 Cluster: Linear gramicidin synthetase subunit C ... 56 7e-06
UniRef50_Q6D738 Cluster: Non-ribosomal peptide synthetase; n=3; ... 55 9e-06
UniRef50_Q4ZT75 Cluster: Amino acid adenylation; n=2; Pseudomona... 55 9e-06
UniRef50_Q7N2F7 Cluster: Complete genome; segment 11/17; n=4; Ph... 55 1e-05
UniRef50_A4X8Q7 Cluster: AMP-dependent synthetase and ligase; n=... 54 2e-05
UniRef50_Q9HYR8 Cluster: Probable non-ribosomal peptide syntheta... 54 2e-05
UniRef50_Q6DNE7 Cluster: CurF; n=1; Lyngbya majuscula|Rep: CurF ... 54 2e-05
UniRef50_Q50E74 Cluster: Peptide synthetase 1; n=3; Streptomyces... 54 2e-05
UniRef50_A4FD53 Cluster: Putative non-ribosomal peptide syntheta... 54 2e-05
UniRef50_A0QHN3 Cluster: Syringomycin synthetase; n=3; Mycobacte... 54 2e-05
UniRef50_Q0RVL7 Cluster: Fatty-acid--CoA ligase; n=1; Rhodococcu... 54 3e-05
UniRef50_A7GPR4 Cluster: AMP-dependent synthetase and ligase; n=... 54 3e-05
UniRef50_Q2H8G3 Cluster: Putative uncharacterized protein; n=1; ... 54 3e-05
UniRef50_Q881Q3 Cluster: Non-ribosomal peptide synthetase, termi... 53 4e-05
UniRef50_Q606X9 Cluster: Non-ribosomal peptide synthetase; n=1; ... 53 4e-05
UniRef50_Q3M5Z4 Cluster: AMP-dependent synthetase and ligase; n=... 53 4e-05
UniRef50_Q5IW58 Cluster: Phosphinothricin tripeptide synthetase ... 53 4e-05
UniRef50_Q8DTJ2 Cluster: Putative peptide synthetase; n=1; Strep... 53 5e-05
UniRef50_Q2SG85 Cluster: Acyl-CoA synthetases (AMP-forming)/AMP-... 53 5e-05
UniRef50_Q08QA2 Cluster: Linear gramicidin synthetase subunit B;... 53 5e-05
UniRef50_A1G2R8 Cluster: Amino acid adenylation domain; n=1; Sal... 53 5e-05
UniRef50_Q0CTP0 Cluster: Predicted protein; n=2; Aspergillus|Rep... 53 5e-05
UniRef50_Q8VQF8 Cluster: Peptide synthetase XpsB; n=1; Xenorhabd... 52 6e-05
UniRef50_A4KVL6 Cluster: Non-ribosomal peptide synthetase module... 52 6e-05
UniRef50_UPI0000DAE7B3 Cluster: hypothetical protein Rgryl_01001... 52 8e-05
UniRef50_Q7N1E2 Cluster: Similar to proteins involved in antibio... 52 8e-05
UniRef50_Q3WHQ1 Cluster: Non-ribosomal peptide synthase:Amino ac... 52 8e-05
UniRef50_Q02HM0 Cluster: Putative non-ribosomal peptide syntheta... 52 8e-05
UniRef50_A7F7R1 Cluster: Putative uncharacterized protein; n=1; ... 52 8e-05
UniRef50_Q3KE51 Cluster: Amino acid adenylation; n=7; Pseudomona... 52 1e-04
UniRef50_Q0SK68 Cluster: Non-ribosomal peptide synthetase; n=1; ... 52 1e-04
UniRef50_A4KUB7 Cluster: TlmIV; n=3; root|Rep: TlmIV - Streptoal... 52 1e-04
UniRef50_A4C380 Cluster: Putative uncharacterized protein; n=1; ... 52 1e-04
UniRef50_Q0CCY6 Cluster: Predicted protein; n=2; Pezizomycotina|... 52 1e-04
UniRef50_UPI0001597892 Cluster: NrsF; n=1; Bacillus amyloliquefa... 51 1e-04
UniRef50_Q0TDD6 Cluster: AMP-dependent synthetase; n=19; Enterob... 51 1e-04
UniRef50_Q0RMQ4 Cluster: Putative non-ribosomal peptide syntheta... 51 1e-04
UniRef50_A6Y0W4 Cluster: Yersiniabactin non-ribosomal peptide sy... 51 1e-04
UniRef50_Q8CJX2 Cluster: CDA peptide synthetase III; n=3; Strept... 51 2e-04
UniRef50_A0QH53 Cluster: Linear gramicidin synthetase subunit D;... 51 2e-04
UniRef50_Q93H68 Cluster: Non-ribosomal peptide synthetase; n=1; ... 50 3e-04
UniRef50_A6LQ10 Cluster: Amino acid adenylation domain; n=1; Clo... 50 3e-04
UniRef50_Q5SBL2 Cluster: Equisetin synthetase; n=1; Fusarium het... 50 3e-04
UniRef50_Q9Z4X6 Cluster: CDA peptide synthetase I; n=4; cellular... 50 3e-04
UniRef50_Q9R686 Cluster: Gramicidin S synthetase 2, GRSB; n=1; B... 50 3e-04
UniRef50_Q0B1F7 Cluster: Amino acid adenylation domain; n=2; Bac... 50 3e-04
UniRef50_O30408 Cluster: Tyrocidine synthetase 2 (Tyrocidine syn... 50 3e-04
UniRef50_A3P7D6 Cluster: Non-ribosomal peptide synthase; n=34; B... 50 4e-04
UniRef50_A1CFN0 Cluster: Nonribosomal peptide synthase, putative... 50 4e-04
UniRef50_Q0VMQ7 Cluster: Peptide synthetase, putative; n=1; Alca... 49 6e-04
UniRef50_Q0PH94 Cluster: MassC; n=1; Pseudomonas fluorescens|Rep... 49 6e-04
UniRef50_A7IZW2 Cluster: OciB; n=1; Planktothrix agardhii NIVA-C... 49 6e-04
UniRef50_A4XWA8 Cluster: Amino acid adenylation domain; n=1; Pse... 49 6e-04
UniRef50_A0ZF82 Cluster: Non-ribosomal peptide synthase; n=2; No... 49 6e-04
UniRef50_Q0UX94 Cluster: Putative uncharacterized protein; n=1; ... 49 6e-04
UniRef50_Q83Z53 Cluster: Putisolvin synthetase; n=3; Bacteria|Re... 49 8e-04
UniRef50_Q5ZPA7 Cluster: TubE protein; n=1; Angiococcus discifor... 49 8e-04
UniRef50_A1KAD3 Cluster: Putative long chain fatty acid coA liga... 49 8e-04
UniRef50_Q0LKI7 Cluster: AMP-dependent synthetase and ligase; n=... 48 0.001
UniRef50_Q5D6D6 Cluster: Nonribosomal peptide synthetase 3; n=3;... 48 0.001
UniRef50_O30409 Cluster: Tyrocidine synthetase 3 (Tyrocidine syn... 48 0.001
UniRef50_Q7N1E3 Cluster: Similar to proteins involved in antibio... 48 0.001
UniRef50_Q6D739 Cluster: Non-ribosomal peptide synthetase; n=3; ... 48 0.001
UniRef50_Q2SHZ4 Cluster: Non-ribosomal peptide synthetase module... 48 0.001
UniRef50_Q2VQ15 Cluster: Nonribosomal peptide synthetase C; n=3;... 48 0.001
UniRef50_Q1YTY5 Cluster: Long-chain-fatty-acid--CoA ligase; n=2;... 48 0.001
UniRef50_Q0RL74 Cluster: Putative long-chain-fatty-acid CoA liga... 48 0.001
UniRef50_A0UVH5 Cluster: Amino acid adenylation domain; n=2; Bac... 48 0.001
UniRef50_A0NTU6 Cluster: Putative non-ribosomal peptide syntheta... 48 0.001
UniRef50_UPI00015B53A6 Cluster: PREDICTED: similar to AMP depend... 48 0.002
UniRef50_Q5YPH7 Cluster: Putative non-ribosomal peptide syntheta... 48 0.002
UniRef50_A5N8C2 Cluster: Predicted nonribosomal peptide syntheta... 48 0.002
UniRef50_A3TIE6 Cluster: FadD13; n=2; Actinomycetales|Rep: FadD1... 48 0.002
UniRef50_Q2SGN2 Cluster: Non-ribosomal peptide synthetase module... 47 0.002
UniRef50_Q3EYR3 Cluster: Peptide synthetase; n=3; Bacillus cereu... 47 0.002
UniRef50_A4C379 Cluster: Non-ribosomal peptide synthetase, termi... 47 0.002
UniRef50_A3I9A7 Cluster: Peptide synthetase; n=1; Bacillus sp. B... 47 0.002
UniRef50_Q4ZT69 Cluster: Amino acid adenylation; n=8; cellular o... 47 0.003
UniRef50_Q4KAY8 Cluster: Pyochelin synthetase F; n=1; Pseudomona... 47 0.003
UniRef50_Q2SW14 Cluster: Peptide synthetase, putative; n=1; Burk... 47 0.003
UniRef50_Q6HXY8 Cluster: AMP-binding enzyme; n=10; Bacillus cere... 47 0.003
UniRef50_Q5DIV7 Cluster: PvdI; n=5; Pseudomonas aeruginosa|Rep: ... 47 0.003
UniRef50_Q21UY9 Cluster: AMP-dependent synthetase and ligase; n=... 47 0.003
UniRef50_Q0PH95 Cluster: MassB; n=2; Pseudomonas fluorescens|Rep... 47 0.003
UniRef50_Q08ST3 Cluster: Saframycin Mx1 synthetase B; n=1; Stigm... 47 0.003
UniRef50_A3P7D5 Cluster: Non-ribosomal peptide synthase; n=21; B... 47 0.003
UniRef50_Q1EPL2 Cluster: AMP-dependent synthetase and ligase fam... 47 0.003
UniRef50_Q54P77 Cluster: 4-coumarate-CoA ligase; n=3; Dictyostel... 47 0.003
UniRef50_Q9L8H4 Cluster: Actinomycin synthetase III; n=1; Strept... 46 0.004
UniRef50_Q9KIZ9 Cluster: EpoB; n=2; Sorangium cellulosum|Rep: Ep... 46 0.004
UniRef50_Q9F0D7 Cluster: Thaxtomin synthetase B; n=2; Streptomyc... 46 0.004
UniRef50_Q0RWB4 Cluster: Long-chain-fatty-acid--CoA ligase; n=5;... 46 0.004
UniRef50_Q0LPK1 Cluster: Amino acid adenylation; n=1; Herpetosip... 46 0.004
UniRef50_A4BRH2 Cluster: Amino acid adenylation; n=1; Nitrococcu... 46 0.004
UniRef50_A3INW8 Cluster: Peptide synthetase; n=3; Chroococcales|... 46 0.004
UniRef50_A0JZK7 Cluster: Amino acid adenylation domain; n=1; Art... 46 0.004
UniRef50_P39846 Cluster: Peptide synthetase 2; n=5; Bacillus|Rep... 46 0.004
UniRef50_Q8U9Q1 Cluster: Peptide synthetase; n=1; Agrobacterium ... 46 0.006
UniRef50_Q4KAY7 Cluster: Pyochelin synthetase E; n=1; Pseudomona... 46 0.006
UniRef50_Q8GGR4 Cluster: Nonribosomal peptide synthetase; n=1; S... 46 0.006
UniRef50_Q7CRI7 Cluster: AGR_L_3476p; n=2; Agrobacterium tumefac... 46 0.006
UniRef50_Q5V8A8 Cluster: LtxA; n=1; Lyngbya majuscula|Rep: LtxA ... 46 0.006
UniRef50_Q50E73 Cluster: Peptide synthetase 2; n=1; Streptomyces... 46 0.006
UniRef50_A6VYF8 Cluster: Amino acid adenylation domain; n=1; Mar... 46 0.006
UniRef50_A6GK66 Cluster: Non-ribosomal peptide synthetase; n=1; ... 46 0.006
UniRef50_P27743 Cluster: N-(5-amino-5-carboxypentanoyl)-L-cystei... 46 0.006
UniRef50_Q5YPH6 Cluster: Putative non-ribosomal peptide syntheta... 46 0.007
UniRef50_Q3WDU5 Cluster: Amino acid adenylation; n=1; Frankia sp... 46 0.007
UniRef50_Q3DZ13 Cluster: AMP-dependent synthetase and ligase; n=... 46 0.007
UniRef50_Q2AZ45 Cluster: Amino acid adenylation; n=2; Bacillus c... 46 0.007
UniRef50_Q0S7I5 Cluster: Non-ribosomal peptide synthetase; n=1; ... 46 0.007
UniRef50_Q0B1F5 Cluster: Amino acid adenylation domain; n=1; Bur... 46 0.007
UniRef50_A4D933 Cluster: CrpA; n=3; Cyanobacteria|Rep: CrpA - No... 46 0.007
UniRef50_A3IP47 Cluster: Peptide synthetase; n=2; Cyanobacteria|... 46 0.007
UniRef50_Q9C440 Cluster: Peptide synthetase; n=1; Trichoderma as... 46 0.007
UniRef50_Q8DTJ7 Cluster: Putative surfactin synthetase; n=1; Str... 45 0.010
UniRef50_Q63CQ6 Cluster: Multifunctional nonribosomal peptide sy... 45 0.010
UniRef50_Q840C8 Cluster: Catechol siderophore synthase DhbF-like... 45 0.010
UniRef50_Q1DCS5 Cluster: Non-ribosomal peptide synthetase; n=1; ... 45 0.010
UniRef50_Q1D6B8 Cluster: Non-ribosomal peptide synthetase; n=5; ... 45 0.010
UniRef50_A4Z4I9 Cluster: McnE; n=5; Cyanobacteria|Rep: McnE - Mi... 45 0.010
UniRef50_A3PQV8 Cluster: AMP-dependent synthetase and ligase; n=... 45 0.010
UniRef50_A3IBP2 Cluster: Peptide synthetase; n=1; Bacillus sp. B... 45 0.010
UniRef50_Q5D0Q8 Cluster: Nonribosomal peptide synthetase 10; n=1... 45 0.010
UniRef50_Q4WVN4 Cluster: Nonribosomal peptide synthase, putative... 45 0.010
UniRef50_Q2HBM7 Cluster: Putative uncharacterized protein; n=1; ... 45 0.010
UniRef50_Q0CPR1 Cluster: Predicted protein; n=1; Aspergillus ter... 45 0.010
UniRef50_A1CCA1 Cluster: Nonribosomal peptide synthase SidE; n=5... 45 0.010
UniRef50_Q9EWP5 Cluster: Putative non-ribosomal peptide synthase... 45 0.013
UniRef50_Q8DTJ5 Cluster: Putative bacitracin synthetase 1; BacA;... 45 0.013
UniRef50_Q0VNL6 Cluster: Non-ribosomal peptide synthase; n=1; Al... 45 0.013
UniRef50_Q0FLF0 Cluster: Acetyl-CoA synthetase; n=1; Roseovarius... 45 0.013
UniRef50_A3Q3X0 Cluster: AMP-dependent synthetase and ligase; n=... 45 0.013
UniRef50_A1G504 Cluster: Amino acid adenylation domain; n=1; Sal... 45 0.013
UniRef50_Q45R85 Cluster: Peptide synthetase; n=2; Actinomycetale... 44 0.017
UniRef50_Q0MYM1 Cluster: Nonribosomal peptide synthetase; n=2; L... 44 0.017
UniRef50_Q09D72 Cluster: Linear gramicidin synthetase subunit D;... 44 0.017
UniRef50_Q094I7 Cluster: Aminotransferase, class III family; n=9... 44 0.017
UniRef50_A5CMR7 Cluster: Non-ribosomal peptide synthetase; n=1; ... 44 0.017
UniRef50_A4D935 Cluster: CrpC; n=1; Nostoc sp. ATCC 53789|Rep: C... 44 0.017
UniRef50_A3VWM8 Cluster: Acyl-CoA synthase; n=4; Proteobacteria|... 44 0.017
UniRef50_A3DK40 Cluster: AMP-dependent synthetase and ligase; n=... 44 0.017
UniRef50_A1ZLW0 Cluster: Bacitracin synthetase 1 (BA1), putative... 44 0.017
UniRef50_A1G2S8 Cluster: Amino acid adenylation domain; n=1; Sal... 44 0.017
UniRef50_A0ZF79 Cluster: Non-ribosomal peptide synthase; n=6; Cy... 44 0.017
UniRef50_A0PTU7 Cluster: Non-ribosomal peptide synthetase MbtF; ... 44 0.017
UniRef50_A7ELI8 Cluster: Putative uncharacterized protein; n=1; ... 44 0.017
UniRef50_Q7NDN7 Cluster: Glr4198 protein; n=1; Gloeobacter viola... 44 0.022
UniRef50_Q73YU2 Cluster: Putative uncharacterized protein; n=1; ... 44 0.022
UniRef50_O69825 Cluster: Putative peptide synthase; n=1; Strepto... 44 0.022
UniRef50_Q84BC7 Cluster: NcpB; n=3; Cyanobacteria|Rep: NcpB - No... 44 0.022
UniRef50_Q6WZB2 Cluster: Nonribosomal peptide synthetase; n=1; S... 44 0.022
UniRef50_Q3WFP5 Cluster: AMP-dependent synthetase and ligase; n=... 44 0.022
UniRef50_A1T3N1 Cluster: AMP-dependent synthetase and ligase; n=... 44 0.022
UniRef50_A5BPU4 Cluster: Putative uncharacterized protein; n=1; ... 44 0.022
UniRef50_O16481 Cluster: Putative uncharacterized protein; n=3; ... 44 0.022
UniRef50_A2QAK0 Cluster: Similarity: the ORF shows similarity to... 44 0.022
UniRef50_P26046 Cluster: N-(5-amino-5-carboxypentanoyl)-L-cystei... 44 0.022
UniRef50_Q63CQ5 Cluster: Multifunctional nonribosomal peptide sy... 44 0.029
UniRef50_Q2SKG0 Cluster: Non-ribosomal peptide synthetase module... 44 0.029
UniRef50_Q93N86 Cluster: Peptide synthetase; n=2; Actinomycetale... 44 0.029
UniRef50_Q6YK39 Cluster: Bacillomycin D synthetase C; n=4; Bacil... 44 0.029
UniRef50_Q3WG49 Cluster: AMP-dependent synthetase and ligase pre... 44 0.029
UniRef50_Q0S7A8 Cluster: 2,3-dihydroxybenzoate-AMP ligase/ S-dih... 44 0.029
UniRef50_Q0LP42 Cluster: Amino acid adenylation; n=1; Herpetosip... 44 0.029
UniRef50_Q0LIS9 Cluster: Amino acid adenylation; n=1; Herpetosip... 44 0.029
UniRef50_P94873 Cluster: Alpha-aminoadipyl-cysteinyl-valine synt... 44 0.029
UniRef50_A6ASZ6 Cluster: Enterobactin synthetase component F; n=... 44 0.029
UniRef50_A5UV13 Cluster: AMP-dependent synthetase and ligase; n=... 44 0.029
UniRef50_A4C385 Cluster: Amino acid adenylation; n=6; Pseudoalte... 44 0.029
UniRef50_A4C382 Cluster: Amino acid adenylation; n=1; Pseudoalte... 44 0.029
UniRef50_Q8CUP9 Cluster: Long-chain fatty-acid-CoA ligase; n=1; ... 43 0.039
UniRef50_Q5KW69 Cluster: Long-chain fatty-acid-CoA ligase; n=1; ... 43 0.039
UniRef50_Q643C6 Cluster: Mannopeptimycin peptide synthetase MppB... 43 0.039
UniRef50_Q2AZG3 Cluster: Non-ribosomal peptide synthase:Amino ac... 43 0.039
UniRef50_Q2ANW8 Cluster: Non-ribosomal peptide synthase:Amino ac... 43 0.039
UniRef50_Q24N89 Cluster: Putative uncharacterized protein; n=1; ... 43 0.039
UniRef50_Q1DBW8 Cluster: Putative non-ribosomal peptide syntheta... 43 0.039
UniRef50_Q1D3L0 Cluster: Non-ribosomal peptide synthase; n=1; My... 43 0.039
UniRef50_Q0SE34 Cluster: Non-ribosomal peptide synthetase; n=1; ... 43 0.039
UniRef50_O68487 Cluster: Actinomycin synthetase II; n=1; Strepto... 43 0.039
UniRef50_A4BLS2 Cluster: Pyochelin synthetase F; n=2; Proteobact... 43 0.039
UniRef50_A3JMY8 Cluster: Non-ribosomal peptide synthetase; n=4; ... 43 0.039
UniRef50_A2VNP9 Cluster: Fatty-acid-CoA ligase fadD13; n=7; Myco... 43 0.039
UniRef50_A1G2S7 Cluster: Amino acid adenylation domain; n=1; Sal... 43 0.039
UniRef50_A0ZL89 Cluster: Non-ribosomal peptide synthase; n=1; No... 43 0.039
UniRef50_A0ZF81 Cluster: Amino acid adenylation protein; n=3; Ba... 43 0.039
UniRef50_Q81DB7 Cluster: Peptide synthetase; n=4; Bacillus cereu... 43 0.051
UniRef50_Q5ZTI3 Cluster: Peptide synthetase, non-ribosomal; n=2;... 43 0.051
UniRef50_Q0SEB1 Cluster: Non-ribosomal peptide synthetase; n=2; ... 43 0.051
UniRef50_Q6SK65 Cluster: Peptide synthetase; n=5; cellular organ... 43 0.051
UniRef50_Q2VQ12 Cluster: Nonribosomal peptide synthetase F; n=1;... 43 0.051
UniRef50_A6FX12 Cluster: Putative long-chain fatty acid--CoA lig... 43 0.051
UniRef50_A5MZS3 Cluster: Predicted NRPS adenylation domain; n=1;... 43 0.051
UniRef50_A4XCB6 Cluster: AMP-dependent synthetase and ligase; n=... 43 0.051
UniRef50_A3HT18 Cluster: Putative acyl-CoA synthetase; n=1; Algo... 43 0.051
UniRef50_A3DGP7 Cluster: Amino acid adenylation domain; n=1; Clo... 43 0.051
UniRef50_A1R682 Cluster: Putative hydrolase/AMP-binding domain p... 43 0.051
UniRef50_A2Q968 Cluster: Contig An01c0240, complete genome; n=1;... 43 0.051
UniRef50_Q5V498 Cluster: Acyl-coenzyme A synthetases; n=5; Halob... 43 0.051
UniRef50_P19828 Cluster: Protein angR; n=5; Vibrionaceae|Rep: Pr... 43 0.051
UniRef50_Q8GAQ3 Cluster: BarG; n=1; Lyngbya majuscula|Rep: BarG ... 42 0.068
UniRef50_Q1D3T0 Cluster: Non-ribosomal peptide synthase MxaA; n=... 42 0.068
UniRef50_Q0P7K1 Cluster: Putative hybrid non-ribosomal peptide-p... 42 0.068
UniRef50_Q0P7K0 Cluster: Putative non-ribosomal peptide synthase... 42 0.068
UniRef50_A5CSZ9 Cluster: Putative acyl-CoA synthetase; n=1; Clav... 42 0.068
UniRef50_A3YFF6 Cluster: Amino acid adenylation; n=2; Bacteria|R... 42 0.068
UniRef50_A3KI35 Cluster: Putative peptide synthetase; n=1; Strep... 42 0.068
UniRef50_Q09164 Cluster: Cyclosporine synthetase; n=8; Fungi/Met... 42 0.068
UniRef50_Q70LM7 Cluster: Linear gramicidin synthetase subunit A ... 42 0.068
UniRef50_Q9RTR4 Cluster: Long-chain fatty acid--CoA ligase; n=4;... 42 0.090
UniRef50_Q3JQV3 Cluster: Nonribosomal peptide synthetase; n=24; ... 42 0.090
UniRef50_Q8VQF9 Cluster: Peptide synthetase XpsA; n=1; Xenorhabd... 42 0.090
UniRef50_Q6E7J5 Cluster: JamO; n=1; Lyngbya majuscula|Rep: JamO ... 42 0.090
UniRef50_Q4C3C0 Cluster: Non-ribosomal peptide synthase:Amino ac... 42 0.090
UniRef50_A4F9A3 Cluster: Putative non-ribosomal peptide syntheta... 42 0.090
UniRef50_A0PWU0 Cluster: Polyketide synthase Pks16_1; n=1; Mycob... 42 0.090
UniRef50_A5C150 Cluster: Putative uncharacterized protein; n=7; ... 42 0.090
UniRef50_Q8ESG9 Cluster: Long-chain fatty-acid-CoA ligase; n=1; ... 42 0.12
UniRef50_Q8EN24 Cluster: AMP-binding enzyme; n=1; Oceanobacillus... 42 0.12
UniRef50_Q9LAS7 Cluster: Putative uncharacterized protein; n=1; ... 42 0.12
UniRef50_Q7BQ71 Cluster: Peptide synthetase-like protein; n=1; B... 42 0.12
UniRef50_Q1DC43 Cluster: Putative long-chain-fatty-acid CoA liga... 42 0.12
UniRef50_Q1D3L3 Cluster: Non-ribosomal peptide synthase; n=1; My... 42 0.12
UniRef50_Q12IB9 Cluster: Amino acid adenylation; n=3; cellular o... 42 0.12
UniRef50_Q0P7J2 Cluster: Putative hybrid polyketide-non-ribosoma... 42 0.12
UniRef50_A5N8Z4 Cluster: Predicted hybrid nonribosomal peptide s... 42 0.12
UniRef50_A5EJ32 Cluster: Putative non-ribosomal peptide synthase... 42 0.12
UniRef50_A1FGJ5 Cluster: Amino acid adenylation; n=1; Pseudomona... 42 0.12
UniRef50_Q6RKE1 Cluster: Polyketide synthase; n=1; Cochliobolus ... 42 0.12
UniRef50_A1DA53 Cluster: Nonribosomal peptide synthase, putative... 42 0.12
UniRef50_UPI000050FA69 Cluster: COG0318: Acyl-CoA synthetases (A... 41 0.16
UniRef50_Q93H58 Cluster: Non-ribosomal peptide synthetase; n=1; ... 41 0.16
UniRef50_Q5YQK2 Cluster: Putative acyl-CoA synthetase; n=1; Noca... 41 0.16
UniRef50_Q311J1 Cluster: Amino acid adenylation; n=9; Bacteria|R... 41 0.16
UniRef50_Q3WFS6 Cluster: AMP-dependent synthetase and ligase; n=... 41 0.16
UniRef50_Q18ZS4 Cluster: Amino acid adenylation domain; n=2; Des... 41 0.16
UniRef50_Q110E8 Cluster: Amino acid adenylation domain; n=1; Tri... 41 0.16
UniRef50_Q0AL69 Cluster: AMP-dependent synthetase and ligase; n=... 41 0.16
UniRef50_A7KAU1 Cluster: Acyl-CoA synthetase/AMP-acid ligase; n=... 41 0.16
UniRef50_A6LR92 Cluster: AMP-dependent synthetase and ligase; n=... 41 0.16
UniRef50_A6E8C1 Cluster: Amino acid adenylation; n=1; Pedobacter... 41 0.16
UniRef50_A5A9U3 Cluster: Mps2 protein; n=2; Mycobacterium|Rep: M... 41 0.16
UniRef50_A4XD38 Cluster: Amino acid adenylation domain; n=2; Sal... 41 0.16
UniRef50_A4IXC6 Cluster: Amino acid adenylase; n=10; Francisella... 41 0.16
UniRef50_A3YGJ0 Cluster: Amino acid adenylation; n=1; Marinomona... 41 0.16
UniRef50_Q73VY7 Cluster: FadD13; n=2; Mycobacterium avium|Rep: F... 41 0.21
UniRef50_Q6LGA3 Cluster: Hypothetical peptide synthetase; n=1; P... 41 0.21
UniRef50_Q2JBN8 Cluster: AMP-dependent synthetase and ligase; n=... 41 0.21
UniRef50_Q84BC8 Cluster: NcpA; n=5; Cyanobacteria|Rep: NcpA - No... 41 0.21
UniRef50_Q333V5 Cluster: NRPS protein; n=2; Actinomycetales|Rep:... 41 0.21
UniRef50_Q1EDB0 Cluster: HctF; n=3; Cyanobacteria|Rep: HctF - Ly... 41 0.21
UniRef50_A5I518 Cluster: Putative AMP-binding enzyme; n=4; Clost... 41 0.21
UniRef50_Q88L97 Cluster: Long-chain-fatty-acid--CoA ligase, puta... 40 0.27
UniRef50_Q6AJW6 Cluster: Probable peptide synthase; n=1; Desulfo... 40 0.27
UniRef50_Q7D791 Cluster: Peptide synthetase; n=18; Mycobacterium... 40 0.27
UniRef50_Q0S3T3 Cluster: CoA synthetase; n=1; Rhodococcus sp. RH... 40 0.27
UniRef50_A7IJ32 Cluster: Amino acid adenylation domain; n=1; Xan... 40 0.27
UniRef50_A5V009 Cluster: AMP-dependent synthetase and ligase; n=... 40 0.27
UniRef50_A0V6U0 Cluster: Amino acid adenylation domain; n=1; Del... 40 0.27
UniRef50_A0UVH8 Cluster: Amino acid adenylation domain; n=1; Clo... 40 0.27
UniRef50_Q0DV32 Cluster: Os03g0152400 protein; n=5; Magnoliophyt... 40 0.27
UniRef50_Q2VJ20 Cluster: Putative nonribosomal peptide synthetas... 40 0.27
UniRef50_A6RPX2 Cluster: Putative uncharacterized protein; n=1; ... 40 0.27
UniRef50_A5AAC0 Cluster: Contig An02c0310, complete genome; n=1;... 40 0.27
UniRef50_Q3IQ14 Cluster: Acyl-CoA synthetase II 4; n=1; Natronom... 40 0.27
UniRef50_P40806 Cluster: Putative polyketide synthase pksJ; n=9;... 40 0.27
UniRef50_Q2JA64 Cluster: Amino acid adenylation; n=3; Actinomyce... 40 0.36
UniRef50_Q93I56 Cluster: Iturin A synthetase A; n=6; Bacillus|Re... 40 0.36
UniRef50_Q0VMQ8 Cluster: Peptide synthetase, putative; n=1; Alca... 40 0.36
UniRef50_A6VYF7 Cluster: Amino acid adenylation domain; n=1; Mar... 40 0.36
UniRef50_A5W120 Cluster: Amino acid adenylation domain; n=3; Bac... 40 0.36
UniRef50_A0UUS2 Cluster: Amino acid adenylation domain; n=5; roo... 40 0.36
UniRef50_A0QZG7 Cluster: AMP-dependent synthetase and ligase; n=... 40 0.36
UniRef50_Q0CBB5 Cluster: Predicted protein; n=2; Aspergillus|Rep... 40 0.36
UniRef50_A1CPQ3 Cluster: Equisetin synthetase, putative; n=1; As... 40 0.36
UniRef50_O28347 Cluster: Long-chain-fatty-acid--CoA ligase; n=1;... 40 0.36
UniRef50_P29698 Cluster: Enterobactin synthetase component F; n=... 40 0.36
UniRef50_UPI000038E5D3 Cluster: hypothetical protein Faci_030000... 40 0.48
UniRef50_Q8YWC0 Cluster: All1695 protein; n=1; Nostoc sp. PCC 71... 40 0.48
UniRef50_Q8R8N5 Cluster: Acyl-CoA synthetases (AMP-forming)/AMP-... 40 0.48
UniRef50_Q7WNN5 Cluster: Putative long-chain-fatty-acid-CoA liga... 40 0.48
UniRef50_Q5YU36 Cluster: Putative peptide synthetase; n=1; Nocar... 40 0.48
UniRef50_Q53005 Cluster: 4-hydroxybenzoate: coenzyme A ligase; n... 40 0.48
UniRef50_Q2JBJ2 Cluster: Amino acid adenylation; n=1; Frankia sp... 40 0.48
UniRef50_Q9K5M1 Cluster: Peptide synthetase; n=8; Bacteria|Rep: ... 40 0.48
UniRef50_Q6VT95 Cluster: Mixed type I polyketide synthase/nonrib... 40 0.48
UniRef50_Q5DIP4 Cluster: PvdJ; n=19; root|Rep: PvdJ - Pseudomona... 40 0.48
UniRef50_Q45R83 Cluster: Peptide synthetase; n=3; Actinobacteria... 40 0.48
UniRef50_Q0SKF6 Cluster: Non-ribosomal peptide synthetase; n=2; ... 40 0.48
UniRef50_Q0LPK3 Cluster: AMP-dependent synthetase and ligase; n=... 40 0.48
UniRef50_Q0LKI6 Cluster: Amino acid adenylation; n=1; Herpetosip... 40 0.48
UniRef50_A6DTG5 Cluster: Peptide synthase; n=1; Lentisphaera ara... 40 0.48
UniRef50_A5FI48 Cluster: Amino acid adenylation domain; n=2; cel... 40 0.48
UniRef50_A4XEW6 Cluster: AMP-dependent synthetase and ligase; n=... 40 0.48
UniRef50_A4F3K7 Cluster: Non-ribosomal peptide synthetase; n=3; ... 40 0.48
UniRef50_A1WKM6 Cluster: Amino acid adenylation domain; n=17; Pr... 40 0.48
UniRef50_A0IT99 Cluster: Amino acid adenylation domain; n=1; Ser... 40 0.48
UniRef50_Q42879 Cluster: 4-coumarate:CoA ligase; n=25; Spermatop... 40 0.48
UniRef50_Q17GP6 Cluster: AMP dependent ligase; n=2; Aedes aegypt... 40 0.48
UniRef50_A2E702 Cluster: AMP-binding enzyme family protein; n=2;... 40 0.48
UniRef50_Q5B7I5 Cluster: Putative uncharacterized protein; n=1; ... 40 0.48
UniRef50_Q5AR54 Cluster: Putative uncharacterized protein; n=1; ... 40 0.48
UniRef50_Q0CBJ1 Cluster: Predicted protein; n=1; Aspergillus ter... 40 0.48
UniRef50_A6SDE5 Cluster: Putative uncharacterized protein; n=1; ... 40 0.48
UniRef50_A2R8D2 Cluster: Function: C. carbonum HTS is a multifun... 40 0.48
UniRef50_P45745 Cluster: Dimodular nonribosomal peptide syntheta... 40 0.48
UniRef50_Q4ZVI2 Cluster: Amino acid adenylation; n=4; Pseudomona... 39 0.63
UniRef50_Q39U25 Cluster: AMP-dependent synthetase and ligase; n=... 39 0.63
UniRef50_Q8G982 Cluster: Peptide synthetase; n=102; Cyanobacteri... 39 0.63
UniRef50_Q70AZ6 Cluster: Non-ribosomal peptide synthetase; n=6; ... 39 0.63
UniRef50_Q4C639 Cluster: Amino acid adenylation; n=1; Crocosphae... 39 0.63
UniRef50_Q1D6A0 Cluster: Non-ribosomal peptide synthetase; n=7; ... 39 0.63
UniRef50_Q1D593 Cluster: Non-ribosomal peptide synthetase; n=4; ... 39 0.63
UniRef50_Q13R15 Cluster: Putative long-chain-fatty-acid--CoA lig... 39 0.63
UniRef50_Q0S5J9 Cluster: Ligase; n=3; Bacteria|Rep: Ligase - Rho... 39 0.63
UniRef50_Q0LN68 Cluster: Amino acid adenylation; n=1; Herpetosip... 39 0.63
UniRef50_A7GTG0 Cluster: Amino acid adenylation domain; n=2; Fir... 39 0.63
UniRef50_A5FI53 Cluster: Amino acid adenylation domain; n=2; Bac... 39 0.63
UniRef50_A4A9J5 Cluster: AMP-ligase; n=1; Congregibacter litoral... 39 0.63
UniRef50_A3IZW4 Cluster: Non-ribosomal peptide synthase; n=2; Cy... 39 0.63
UniRef50_A0QZI4 Cluster: Crotonobetaine/carnitine-CoA ligase; n=... 39 0.63
UniRef50_A0FCL0 Cluster: MerP; n=2; Streptomyces|Rep: MerP - Str... 39 0.63
UniRef50_O43103 Cluster: Ferrichrome siderophore peptide synthet... 39 0.63
UniRef50_UPI0000D55D70 Cluster: PREDICTED: similar to CG9009-PA;... 39 0.84
UniRef50_UPI00005F935B Cluster: COG1020: Non-ribosomal peptide s... 39 0.84
UniRef50_Q9AMR5 Cluster: ID930; n=1; Bradyrhizobium japonicum|Re... 39 0.84
>UniRef50_UPI00015B6235 Cluster: PREDICTED: similar to
ENSANGP00000025395; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to ENSANGP00000025395 - Nasonia
vitripennis
Length = 2263
Score = 1755 bits (4351), Expect = 0.0
Identities = 840/1090 (77%), Positives = 922/1090 (84%), Gaps = 26/1090 (2%)
Query: 1 MLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLASVLNGMHVIFIPYALMKVSPAS 60
MLAHCR L+ AC YTEGE+ VCVLDFKRE GLWH+ L S+LNGMHVIFIPYALMKV+PAS
Sbjct: 1181 MLAHCRALTQACGYTEGENAVCVLDFKREVGLWHSTLTSILNGMHVIFIPYALMKVNPAS 1240
Query: 61 WMHMITKHRASIAIVKSRDLHWGLLATRDHKEISLSSLRMLLVADGANPWSLSSCDQFLS 120
WM MITKHRAS+A+VKSRDLHWGLLAT+DHK+ISLS+LR+LLVADGANPWSLSSCDQFLS
Sbjct: 1241 WMQMITKHRASVAVVKSRDLHWGLLATKDHKDISLSTLRLLLVADGANPWSLSSCDQFLS 1300
Query: 121 VFQSKGVRGDAICPCACSSESMTVCIXX-XXXXXXXXXXXVLSMSGLSYGVVRVDAENSL 179
VFQSKG+R DA+CPCA SSE++TV + VLSMSGLS+GVVRVD ENSL
Sbjct: 1301 VFQSKGLRPDAVCPCASSSEALTVSVRRPGRAGVNATGRGVLSMSGLSFGVVRVDQENSL 1360
Query: 180 TSLTLQDCGQVMPSCVIVVVKMEGPAYLCKTDEVGEICVLSGATGSGYWGLPGLTNTVFR 239
TSLTLQDCGQVMP ++ V+KMEGP +CKTDEVGEICV S ATGS YWGL GLTN F+
Sbjct: 1361 TSLTLQDCGQVMPGSIVTVIKMEGPPLVCKTDEVGEICVHSAATGSQYWGLQGLTNNNFK 1420
Query: 240 VRPLDSDGEPIGEEHYVRSXXXXXXXXXXXXXXXXSRDGLMTVTGRKHNMDDIIATVLAV 299
V+PL ++G+P+G+ Y RS SRDGLMTVTGRKHN DDIIATVLAV
Sbjct: 1421 VQPLQAEGQPLGDVEYTRSGLLGFLGPGNLVFVCGSRDGLMTVTGRKHNADDIIATVLAV 1480
Query: 300 EPMKFIYRGRIAVFSVRVLRDERICIVAEQRPDCGEEESFQWMSRVLQAVDSIHQVGIYC 359
EPMKFIYRGRIAVFSVRVLRDERIC+VAEQRPDC EEESFQWMSRVLQAVDSIH VGIYC
Sbjct: 1481 EPMKFIYRGRIAVFSVRVLRDERICVVAEQRPDCSEEESFQWMSRVLQAVDSIHAVGIYC 1540
Query: 360 LALVQPNFLPKTPLGGIHLSECKRRFLEGTLHPSNVLMCPHTCVTNLPKPREIHS----- 414
LALV PN+LPKTPLGGIHLSE KRRFLEGTLHP+NVL+CPHTCVTNLPKPRE+HS
Sbjct: 1541 LALVPPNYLPKTPLGGIHLSETKRRFLEGTLHPANVLLCPHTCVTNLPKPREVHSGKSTN 1600
Query: 415 ------------DVGPASVIVGNLVQGNRLASAQGRDMGYTD-DSDAARKYQFISQILRW 461
DVGPASV+VGN+VQGNRLASAQGRDMG D DSD A+KYQFIS+ILRW
Sbjct: 1601 AKAQISSGDSVSDVGPASVMVGNIVQGNRLASAQGRDMGVLDEDSDNAKKYQFISEILRW 1660
Query: 462 RAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGL 521
RA TSDHVIFT LN+KGAV+ L+C++LHKKAERIGNLLL++GR+NTGDHVAL+FPPG
Sbjct: 1661 RAVGTSDHVIFTSLNSKGAVAASLSCSQLHKKAERIGNLLLDRGRINTGDHVALLFPPGT 1720
Query: 522 DLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKE 581
DLICAFYGCLYVGAVPVTIRPPHPQNL TTLPTVRMIVDVSK+ L+L+NQ+++KLL+SKE
Sbjct: 1721 DLICAFYGCLYVGAVPVTIRPPHPQNLQTTLPTVRMIVDVSKSVLILTNQTILKLLKSKE 1780
Query: 582 ASNVLDSKAWPMTLDTDDMPKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVT 641
A+NV++ K+WP LD DDMPKKKLP++YRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVT
Sbjct: 1781 ANNVVEVKSWPTILDMDDMPKKKLPVLYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVT 1840
Query: 642 SLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIPPSEVEVNPALWL 701
SLCR+MK+ACELYPSRHIALCLDPY GLGFALWCLSSIYSGHHSILIPPSEVE NPALWL
Sbjct: 1841 SLCRAMKLACELYPSRHIALCLDPYSGLGFALWCLSSIYSGHHSILIPPSEVEANPALWL 1900
Query: 702 SAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVVAEERPRINLTNS 761
SAVS +VRDTFCSYGVMELCTKGLGSSV+ LK++G++LACVRTCVVVAEERPRI LT+S
Sbjct: 1901 SAVSHSRVRDTFCSYGVMELCTKGLGSSVHALKARGVSLACVRTCVVVAEERPRIALTSS 1960
Query: 762 FSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPSTVYVDLRALRNDRVSLVERGSP 821
FSKLFSALGLSPRAVSTSFGCRVN AICLQGASSPEPSTVYVDLRALRNDRVSLVERGSP
Sbjct: 1961 FSKLFSALGLSPRAVSTSFGCRVNTAICLQGASSPEPSTVYVDLRALRNDRVSLVERGSP 2020
Query: 822 HSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNASGYFTIYGDESDYADH 881
HSLCLMESGKLLPGVKVI ANPETKGQCGDSHLGEIWVQS HNASGYFTIYGDESDYADH
Sbjct: 2021 HSLCLMESGKLLPGVKVIIANPETKGQCGDSHLGEIWVQSSHNASGYFTIYGDESDYADH 2080
Query: 882 FSAQLVTGNTGEVYARTGYLGFLRRTEIXXXXXXXXXXXXMLPRDSDTDSLASACGSVSI 941
F+A+LVTGNT EVYARTGYLGFLRRTE +P D+ ++ AS V +
Sbjct: 2081 FNARLVTGNTNEVYARTGYLGFLRRTE----SVQQSVGGTDIPGDNVSNVSAS---EVDV 2133
Query: 942 LPDSHDTHDAVFVVGALDETIMLRGMRYHPIDIENSVMRCHKKIAECAVFTWTNLLVVVV 1001
+ HDAVFVVGALDE I+LRGMRYHPIDIENSVMRCHKKIAECAVFTWTNLLVVVV
Sbjct: 2134 ARGDSELHDAVFVVGALDEAILLRGMRYHPIDIENSVMRCHKKIAECAVFTWTNLLVVVV 2193
Query: 1002 ELDGNDSEAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNSRGEKQRMHLRDGFLSDQ 1061
ELDG++SEA NSRGEKQRMHLRDGFL+DQ
Sbjct: 2194 ELDGSESEALDLVALVTSAVLEEHHLVVGVVVVVDPGVVPINSRGEKQRMHLRDGFLADQ 2253
Query: 1062 IDAIYIAYNM 1071
+D IY+AYNM
Sbjct: 2254 LDPIYVAYNM 2263
Score = 123 bits (296), Expect = 3e-26
Identities = 129/510 (25%), Positives = 218/510 (42%), Gaps = 27/510 (5%)
Query: 473 TLLNAKGAVSKVLTCAELHKKAERIGNLLLEKG--RV------NTGDHVALIFPPG--LD 522
T+L+ G + LT +L ++ +I LL K RV GD +AL++P ++
Sbjct: 1002 TVLDPNGKLCVTLTYGKLLSRSYKIAYTLLNKALSRVVGECCLKPGDRIALVYPNDDPIN 1061
Query: 523 LICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEA 582
ICAFYGCL G VPV I P + + ++ + L++++ +K L A
Sbjct: 1062 FICAFYGCLQAGIVPVPIEVPLTRR-DAGSQQIGFLLGSCGIQVALTSEACLKGLPKTAA 1120
Query: 583 SNVLDSKAWPMTLDTDDMPKKKLPIMYRAPTA---EMLAYLDFSVSTTGMLAGIKMSHAA 639
V+ K WP K P + PT + AY++++ G + G+ ++ AA
Sbjct: 1121 GEVIAFKGWPKLHWFVTEHLGKTPKDWMPPTRLTDDTPAYIEYTTDRDGSVMGVTVTRAA 1180
Query: 640 VTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIPPSEVEVNPAL 699
+ + CR++ AC + LD +G L+SI +G H I IP + ++VNPA
Sbjct: 1181 MLAHCRALTQACGYTEGENAVCVLDFKREVGLWHSTLTSILNGMHVIFIPYALMKVNPAS 1240
Query: 700 WLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVVAEERP-RINL 758
W+ +++++ S V++ G + K I+L+ +R +V P ++
Sbjct: 1241 WMQMITKHR-----ASVAVVKSRDLHWGLLATK-DHKDISLSTLRLLLVADGANPWSLSS 1294
Query: 759 TNSFSKLFSALGLSPRAV--STSFGCRVNIAICLQG-ASSPEPSTVYVDLRALRNDRVSL 815
+ F +F + GL P AV S + +++ G A + + L V +
Sbjct: 1295 CDQFLSVFQSKGLRPDAVCPCASSSEALTVSVRRPGRAGVNATGRGVLSMSGLSFGVVRV 1354
Query: 816 VERGSPHSLCLMESGKLLPGVKVITANPETKG-QCGDSHLGEIWVQSPHNASGYFTIYGD 874
+ S SL L + G+++PG V E C +GEI V S S Y+ + G
Sbjct: 1355 DQENSLTSLTLQDCGQVMPGSIVTVIKMEGPPLVCKTDEVGEICVHSAATGSQYWGLQGL 1414
Query: 875 ESDYADHFSAQLVTGNTGEV-YARTGYLGFLRRTEIXXXXXXXXXXXXMLPRDSDTDSLA 933
++ Q G+V Y R+G LGFL + + R + D +
Sbjct: 1415 TNNNFKVQPLQAEGQPLGDVEYTRSGLLGFLGPGNLVFVCGSRDGLMTVTGRKHNADDII 1474
Query: 934 SACGSVSILPDSHDTHDAVFVVGAL-DETI 962
+ +V + + AVF V L DE I
Sbjct: 1475 ATVLAVEPMKFIYRGRIAVFSVRVLRDERI 1504
>UniRef50_Q9W0S9 Cluster: Disco-interacting protein 2; n=16;
Eumetazoa|Rep: Disco-interacting protein 2 - Drosophila
melanogaster (Fruit fly)
Length = 1773
Score = 1536 bits (3807), Expect = 0.0
Identities = 747/1129 (66%), Positives = 874/1129 (77%), Gaps = 61/1129 (5%)
Query: 1 MLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLASVLNGMHVIFIPYALMKVSPAS 60
M+ HCR L++AC+YTEGE +VCVLDFKRE GLWH+VL SVLNGMHVIFIPYALMK+ P+S
Sbjct: 648 MINHCRALTMACHYTEGETIVCVLDFKREVGLWHSVLTSVLNGMHVIFIPYALMKLRPSS 707
Query: 61 WMHMITKHRASIAIVKSRDLHWGLLATRDHKEISLSSLRMLLVADGANPWSLSSCDQFLS 120
WM +ITKHRAS +VKSRDLHWGLLAT+DHK+ISLSSLRMLLVADGANPWSLSSCDQFLS
Sbjct: 708 WMQLITKHRASCCLVKSRDLHWGLLATKDHKDISLSSLRMLLVADGANPWSLSSCDQFLS 767
Query: 121 VFQSKGVRGDAICPCACSSESMTVCIXXXXXXX-----XXXXXXVLSMSGLSYGVVRVDA 175
VFQ+KG+R DAICPCA SSE TV + VLSM+ LS+GVVRVD+
Sbjct: 768 VFQAKGLRSDAICPCASSSEVFTVSLRRPGRGSCGFSPSATGRGVLSMAALSHGVVRVDS 827
Query: 176 ENSLTSLTLQDCGQVMPSCVIVVVKMEGPAYLCKTDEVGEICVLSGATGSGYWGLPGLTN 235
E+SLTSLTLQDCGQVMP+ +VVV+ EGP LCKTD+VGEICV SG+T + Y+GL G+TN
Sbjct: 828 EDSLTSLTLQDCGQVMPAAQMVVVRSEGPPVLCKTDQVGEICVTSGSTSASYFGLDGMTN 887
Query: 236 TVFRVRPL--------DSDG------EPIGEEHYVRSXXXXXXXXXXXXXXXXSRDGLMT 281
+ F+V+PL D +G +PIGE+ YVRS SRDGLMT
Sbjct: 888 STFKVQPLLEELEQPKDGNGTVNIISKPIGEDFYVRSGLLGFLGPGGLVFVCGSRDGLMT 947
Query: 282 VTGRKHNMDDIIATVLAVEPMKFIYRGRIAVFSVRVLRDERICIVAEQRPDCGEEESFQW 341
VTGRKHN DDIIATVLAVEPM+FIYRGRIAVFS++VLRDER+C++AEQRPDC EEESFQW
Sbjct: 948 VTGRKHNADDIIATVLAVEPMRFIYRGRIAVFSIKVLRDERVCVIAEQRPDCSEEESFQW 1007
Query: 342 MSRVLQAVDSIHQVGIYCLALVQPNFLPKTPLGGIHLSECKRRFLEGTLHPSNVLMCPHT 401
MSRVLQAVDSIHQVGIYCLALV PN LPKTPLGGIHL E +RRFLEG+LHP+NVLMCPHT
Sbjct: 1008 MSRVLQAVDSIHQVGIYCLALVPPNHLPKTPLGGIHLCEARRRFLEGSLHPANVLMCPHT 1067
Query: 402 CVTNLPKPREIH-------------------SDVGPASVIVGNLVQGNRLASAQGRDMGY 442
CVTNLPKPRE+H + VGPASV+VGNLVQGNRLA A GRD+G
Sbjct: 1068 CVTNLPKPRELHQGVQTAAKLSSSSGCGITDTGVGPASVMVGNLVQGNRLAEAHGRDVGL 1127
Query: 443 TDDSDAARKYQFISQILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLL 502
+D + RK Q I+ +LRWRA ++ DH+IFTLLN+KGA++K LTC+ELHK+AE+I LL
Sbjct: 1128 AEDCE--RKPQLITGVLRWRANTSPDHIIFTLLNSKGAIAKTLTCSELHKRAEKIAALLQ 1185
Query: 503 EKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVS 562
E+GR+ GDHVALIFPPGLDL+CAFYGCLY+GA+P+TIRPPHPQNL+TTLPTVRMIVDVS
Sbjct: 1186 ERGRIEPGDHVALIFPPGLDLLCAFYGCLYLGAIPITIRPPHPQNLNTTLPTVRMIVDVS 1245
Query: 563 KATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKKLPIMYRAPTAEMLAYLDF 622
K+ +VLS Q +IKLL+S+EA+ +D K WP LD DD PK+K + + + AYLDF
Sbjct: 1246 KSGIVLSIQPIIKLLKSREAATSIDPKTWPPILDIDDNPKRKYAGIATV-SFDSSAYLDF 1304
Query: 623 SVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSG 682
SVST G L+G+ ++H +++SLC S+K+ACELYPSRH+ALCLDPYCGLGF +W L +YSG
Sbjct: 1305 SVSTCGRLSGVNITHRSLSSLCASLKLACELYPSRHVALCLDPYCGLGFVMWTLIGVYSG 1364
Query: 683 HHSILIPPSEVEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLAC 742
HHSILI P EVE NP+LWLS +SQ++VRDTFCSYGV+ELCTK L +S+ LK + I+L C
Sbjct: 1365 HHSILIAPYEVEANPSLWLSTLSQHRVRDTFCSYGVIELCTKALSNSIPSLKQRNIDLRC 1424
Query: 743 VRTCVVVAEERPRINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPSTVY 802
VRTCVVVAEERPR+ LT F KLF ALGL+ R VSTSFGCRVN AIC+QGASS E + VY
Sbjct: 1425 VRTCVVVAEERPRVQLTQQFCKLFQALGLNTRCVSTSFGCRVNPAICVQGASSAESAQVY 1484
Query: 803 VDLRALRNDRVSLVERGSPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSP 862
VD+RALRN+RV+LVERG+P+SLC++ESGKLLPGVKVI ANPETKG CGDSHLGEIWVQ+P
Sbjct: 1485 VDMRALRNNRVALVERGAPNSLCVIESGKLLPGVKVIIANPETKGHCGDSHLGEIWVQAP 1544
Query: 863 HNASGYFTIYGDESDYADHFSAQLVTGNTGEVYARTGYLGFLRRTEIXXXXXXXXXXX-X 921
HNA+GYFTIYGDE+DY DHF+A+LVTG T E+YARTGYLGFLRRTE
Sbjct: 1545 HNANGYFTIYGDETDYNDHFNAKLVTGATSELYARTGYLGFLRRTECSQSASLLDETTPS 1604
Query: 922 MLPRDSDTDSLASAC------GSVSILPDS-------------HDTHDAVFVVGALDETI 962
+ RDSDT+SL S +VS+ +S + HDAV+VVGA+DE I
Sbjct: 1605 VASRDSDTESLNSISQLQLNFSNVSLGGNSEHSLVGGASNANDQELHDAVYVVGAVDEVI 1664
Query: 963 MLRGMRYHPIDIENSVMRCHKKIAECAVFTWTNLLVVVVELDGNDSEAXXXXXXXXXXXX 1022
LRGM YHPIDIENSVMRCHKKIAECAVFTWTNLLVVVVELDGN+SEA
Sbjct: 1665 SLRGMNYHPIDIENSVMRCHKKIAECAVFTWTNLLVVVVELDGNESEALDLVPLVTNTVL 1724
Query: 1023 XXXXXXXXXXXXXXXXXXXXNSRGEKQRMHLRDGFLSDQIDAIYIAYNM 1071
NSRGEKQRMHLRDGFL+DQ+D IY+AYNM
Sbjct: 1725 EDHQLIVGVVVVVDPGVVPINSRGEKQRMHLRDGFLADQLDPIYVAYNM 1773
Score = 117 bits (281), Expect = 2e-24
Identities = 108/425 (25%), Positives = 199/425 (46%), Gaps = 31/425 (7%)
Query: 473 TLLNAKGAVSKVLTCAELHKKAERIGNLL----LEKG----RVNTGDHVALIFPPG--LD 522
T+L+ G V+ LT +L +A++I + L KG + GD VAL++P L
Sbjct: 467 TVLDPNGKVTTTLTYGKLLSRAQKIAHALSTKIFSKGPEQVTLKPGDRVALVYPNNDPLS 526
Query: 523 LICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIK-LLRSKE 581
I A+YGC++ G VP+ I P + T V ++ T+ L++++ +K L +S
Sbjct: 527 FITAWYGCMFRGLVPLPIELPLSSS-DTPPQQVGFLLSSCGITVALTSEACLKGLPKSTT 585
Query: 582 ASNVLDSKAWPMT--LDTDDMPK--KKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSH 637
+ K WP T+ +PK K+ + AY++++ G + G+ ++
Sbjct: 586 TGEIAKLKGWPRLQWFVTEHLPKPPKEFNVGNLRADDSAAAYIEYTTDKEGSVMGVTVTR 645
Query: 638 AAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIPPSEVEVNP 697
AA+ + CR++ +AC I LD +G L+S+ +G H I IP + +++ P
Sbjct: 646 AAMINHCRALTMACHYTEGETIVCVLDFKREVGLWHSVLTSVLNGMHVIFIPYALMKLRP 705
Query: 698 ALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVVAEERP-RI 756
+ W+ ++++ R + C +L GL ++ + K I+L+ +R +V P +
Sbjct: 706 SSWMQLITKH--RASCCLVKSRDL-HWGLLATKDH---KDISLSSLRMLLVADGANPWSL 759
Query: 757 NLTNSFSKLFSALGLSPRAV----STSFGCRVNIAICLQGASSPEPSTV---YVDLRALR 809
+ + F +F A GL A+ S+S V++ +G+ PS + + AL
Sbjct: 760 SSCDQFLSVFQAKGLRSDAICPCASSSEVFTVSLRRPGRGSCGFSPSATGRGVLSMAALS 819
Query: 810 NDRVSLVERGSPHSLCLMESGKLLPGVKVITANPE-TKGQCGDSHLGEIWVQSPHNASGY 868
+ V + S SL L + G+++P +++ E C +GEI V S ++ Y
Sbjct: 820 HGVVRVDSEDSLTSLTLQDCGQVMPAAQMVVVRSEGPPVLCKTDQVGEICVTSGSTSASY 879
Query: 869 FTIYG 873
F + G
Sbjct: 880 FGLDG 884
>UniRef50_Q14689 Cluster: Disco-interacting protein 2 homolog A;
n=116; Coelomata|Rep: Disco-interacting protein 2 homolog
A - Homo sapiens (Human)
Length = 1571
Score = 1299 bits (3218), Expect = 0.0
Identities = 593/910 (65%), Positives = 724/910 (79%), Gaps = 1/910 (0%)
Query: 1 MLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLASVLNGMHVIFIPYALMKVSPAS 60
+LA CR L+ AC Y+E E + VLDFKR+ GLWH VL SV+N MHV+ +PYALMK +P S
Sbjct: 532 LLAQCRALTQACGYSEAETLTNVLDFKRDAGLWHGVLTSVMNRMHVVSVPYALMKANPLS 591
Query: 61 WMHMITKHRASIAIVKSRDLHWGLLATRDHKEISLSSLRMLLVADGANPWSLSSCDQFLS 120
W+ + ++A A+VKSRD+HW LLA R +++SLSSLRML+VADGANPWS+SSCD FL+
Sbjct: 592 WIQKVCFYKARAALVKSRDMHWSLLAQRGQRDVSLSSLRMLIVADGANPWSISSCDAFLN 651
Query: 121 VFQSKGVRGDAICPCACSSESMTVCIXXXXXXXXXX-XXXVLSMSGLSYGVVRVDAENSL 179
VFQS+G+R + ICPCA S E++TV I VLSM+GLSYGV+RVD E L
Sbjct: 652 VFQSRGLRPEVICPCASSPEALTVAIRRPPDLGGPPPRKAVLSMNGLSYGVIRVDTEEKL 711
Query: 180 TSLTLQDCGQVMPSCVIVVVKMEGPAYLCKTDEVGEICVLSGATGSGYWGLPGLTNTVFR 239
+ LT+QD GQVMP + VVK+EG YLCKTDEVGEICV S ATG+ Y+GL G+T VF
Sbjct: 712 SVLTVQDVGQVMPGANVCVVKLEGTPYLCKTDEVGEICVSSSATGTAYYGLLGITKNVFE 771
Query: 240 VRPLDSDGEPIGEEHYVRSXXXXXXXXXXXXXXXXSRDGLMTVTGRKHNMDDIIATVLAV 299
P+ + G PI + + R+ DGLM R+HN DD++AT LAV
Sbjct: 772 AVPVTTGGAPIFDRPFTRTGLLGFIGPDNLVFIVGKLDGLMVTGVRRHNADDVVATALAV 831
Query: 300 EPMKFIYRGRIAVFSVRVLRDERICIVAEQRPDCGEEESFQWMSRVLQAVDSIHQVGIYC 359
EPMKF+YRGRIAVFSV VL D+RI +VAEQRPD EE+SFQWMSRVLQA+DSIHQVG+YC
Sbjct: 832 EPMKFVYRGRIAVFSVTVLHDDRIVLVAEQRPDASEEDSFQWMSRVLQAIDSIHQVGVYC 891
Query: 360 LALVQPNFLPKTPLGGIHLSECKRRFLEGTLHPSNVLMCPHTCVTNLPKPREIHSDVGPA 419
LALV N LPK PLGGIH+SE K+RFLEGTLHP NVLMCPHTCVTNLPKPR+ +VGPA
Sbjct: 892 LALVPANTLPKAPLGGIHISETKQRFLEGTLHPCNVLMCPHTCVTNLPKPRQKQPEVGPA 951
Query: 420 SVIVGNLVQGNRLASAQGRDMGYTDDSDAARKYQFISQILRWRAQSTSDHVIFTLLNAKG 479
S+IVGNLV G R+A A GR++ + +DSD ARK+ F++ +L+WRA +T DH +F LLNAKG
Sbjct: 952 SMIVGNLVAGKRIAQASGRELAHLEDSDQARKFLFLADVLQWRAHTTPDHPLFLLLNAKG 1011
Query: 480 AVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVT 539
V+ TC +LHK+AER+ L+EKGR++ GDHVAL++PPG+DLI AFYGCLY G VPVT
Sbjct: 1012 TVTSTATCVQLHKRAERVAAALMEKGRLSVGDHVALVYPPGVDLIAAFYGCLYCGCVPVT 1071
Query: 540 IRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDD 599
+RPPHPQNL TTLPTV+MIV+VSK+ VL+ Q+V +LLRSKEA+ +D + WP LDTDD
Sbjct: 1072 VRPPHPQNLGTTLPTVKMIVEVSKSACVLTTQAVTRLLRSKEAAAAVDIRTWPTILDTDD 1131
Query: 600 MPKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHI 659
+PKKK+ ++R P+ ++LAYLDFSVSTTG+LAG+KMSHAA ++LCRS+K+ CELYPSR I
Sbjct: 1132 IPKKKIASVFRPPSPDVLAYLDFSVSTTGILAGVKMSHAATSALCRSIKLQCELYPSRQI 1191
Query: 660 ALCLDPYCGLGFALWCLSSIYSGHHSILIPPSEVEVNPALWLSAVSQYKVRDTFCSYGVM 719
A+CLDPYCGLGFALWCL S+YSGH S+L+PP E+E N +LWLSAVSQYK R TFCSY VM
Sbjct: 1192 AICLDPYCGLGFALWCLCSVYSGHQSVLVPPLELESNVSLWLSAVSQYKARVTFCSYSVM 1251
Query: 720 ELCTKGLGSSVNQLKSKGINLACVRTCVVVAEERPRINLTNSFSKLFSALGLSPRAVSTS 779
E+CTKGLG+ L+ KG+NL+CVRTC+VVAEERPRI LT SFSKLF LGL RAVST+
Sbjct: 1252 EMCTKGLGAQTGVLRMKGVNLSCVRTCMVVAEERPRIALTQSFSKLFKDLGLPARAVSTT 1311
Query: 780 FGCRVNIAICLQGASSPEPSTVYVDLRALRNDRVSLVERGSPHSLCLMESGKLLPGVKVI 839
FGCRVN+AICLQG + P+P+TVYVD+RALR+DRV LVERGSPHSL LMESGK+LPGVKVI
Sbjct: 1312 FGCRVNVAICLQGTAGPDPTTVYVDMRALRHDRVRLVERGSPHSLPLMESGKILPGVKVI 1371
Query: 840 TANPETKGQCGDSHLGEIWVQSPHNASGYFTIYGDESDYADHFSAQLVTGNTGEVYARTG 899
A+ ETKG GDSHLGEIWV SPHNA+GY+T+YG+E+ +ADHFSA+L G+T ++ARTG
Sbjct: 1372 IAHTETKGPLGDSHLGEIWVSSPHNATGYYTVYGEEALHADHFSARLSFGDTQTIWARTG 1431
Query: 900 YLGFLRRTEI 909
YLGFLRRTE+
Sbjct: 1432 YLGFLRRTEL 1441
Score = 152 bits (368), Expect = 6e-35
Identities = 73/123 (59%), Positives = 84/123 (68%)
Query: 949 HDAVFVVGALDETIMLRGMRYHPIDIENSVMRCHKKIAECAVFTWTNLLVVVVELDGNDS 1008
HDA++VVG+LDET+ LRGMRYHPIDIE SV+R H+ IAECAVFTWTNLLVVVVELDG +
Sbjct: 1449 HDALYVVGSLDETLELRGMRYHPIDIETSVIRAHRSIAECAVFTWTNLLVVVVELDGLEQ 1508
Query: 1009 EAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNSRGEKQRMHLRDGFLSDQIDAIYIA 1068
+A NSRGEKQRMHLRDGFL+DQ+D IY+A
Sbjct: 1509 DALDLVALVTNVVLEEHYLVVGVVVIVDPGVIPINSRGEKQRMHLRDGFLADQLDPIYVA 1568
Query: 1069 YNM 1071
YNM
Sbjct: 1569 YNM 1571
Score = 111 bits (267), Expect = 1e-22
Identities = 120/539 (22%), Positives = 210/539 (38%), Gaps = 36/539 (6%)
Query: 450 RKYQFISQILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEK----- 504
R ++ + RW + T L+ G LT +L ++ ++ LL K
Sbjct: 331 RPPSLLATLQRWGTTQPKSPCL-TALDTTGKAVYTLTYGKLWSRSLKLAYTLLNKLTSKN 389
Query: 505 -GRVNTGDHVALIFPPG--LDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDV 561
+ GD VAL+FP + + AFYGCL VPV I P + V ++
Sbjct: 390 EPLLKPGDRVALVFPNSDPVMFMVAFYGCLLAELVPVPIEVPLTRK-DAGSQQVGFLLGS 448
Query: 562 SKATLVLSNQSVIKLLRSKEASNVLDSKAWP----MTLDTDDM---PKKKLPIMYRAPTA 614
L L+ + K L + V K WP + +D + PK P+ T
Sbjct: 449 CGVFLALTTDACQKGLPKAQTGEVAAFKGWPPLSWLVIDGKHLAKPPKDWHPLAQDTGTG 508
Query: 615 EMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALW 674
AY+++ S G G+ +SHA++ + CR++ AC + + LD G
Sbjct: 509 T--AYIEYKTSKEGSTVGVTVSHASLLAQCRALTQACGYSEAETLTNVLDFKRDAGLWHG 566
Query: 675 CLSSIYSGHHSILIPPSEVEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLK 734
L+S+ + H + +P + ++ NP W+ V YK R M S + Q
Sbjct: 567 VLTSVMNRMHVVSVPYALMKANPLSWIQKVCFYKARAALVKSRDMH------WSLLAQRG 620
Query: 735 SKGINLACVRTCVVVAEERP-RINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQ-- 791
+ ++L+ +R +V P I+ ++F +F + GL P + + + ++
Sbjct: 621 QRDVSLSSLRMLIVADGANPWSISSCDAFLNVFQSRGLRPEVICPCASSPEALTVAIRRP 680
Query: 792 -GASSPEPSTVYVDLRALRNDRVSLVERGSPHSLCLMESGKLLPGVKVITANPE-TKGQC 849
P P + + L + + L + + G+++PG V E T C
Sbjct: 681 PDLGGPPPRKAVLSMNGLSYGVIRVDTEEKLSVLTVQDVGQVMPGANVCVVKLEGTPYLC 740
Query: 850 GDSHLGEIWVQSPHNASGYFTIYGDESDYADHFSAQLVTGNT---GEVYARTGYLGFLRR 906
+GEI V S + Y+ + G + + + + TG + RTG LGF+
Sbjct: 741 KTDEVGEICVSSSATGTAYYGLLGITKNVFE--AVPVTTGGAPIFDRPFTRTGLLGFIGP 798
Query: 907 TEIXXXXXXXXXXXXMLPRDSDTDSLASACGSVSILPDSHDTHDAVFVVGAL-DETIML 964
+ R + D + + +V + + AVF V L D+ I+L
Sbjct: 799 DNLVFIVGKLDGLMVTGVRRHNADDVVATALAVEPMKFVYRGRIAVFSVTVLHDDRIVL 857
>UniRef50_Q4SKU1 Cluster: Chromosome undetermined SCAF14565, whole
genome shotgun sequence; n=2; Tetraodontidae|Rep:
Chromosome undetermined SCAF14565, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 1584
Score = 1125 bits (2785), Expect = 0.0
Identities = 548/932 (58%), Positives = 683/932 (73%), Gaps = 47/932 (5%)
Query: 5 CRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLASVLNGMHVIFIPYALMKVSPASWMHM 64
C S + E +V VLDFK++ GLW+ +L SV+N MHVI +PY+LMKV+P SW+
Sbjct: 543 CSFNSRPLRLSVAETVVNVLDFKKDVGLWNGILTSVMNMMHVISVPYSLMKVNPLSWIQK 602
Query: 65 ITKHRASIAIVKSRDLHWGLLATRDHKEISLSSLRMLLVADGANPWSLSSCDQFLSVFQS 124
+ +++A +A VKSRD+HW L+A +D K+I+LS L A A S+SSCD FL+VFQ+
Sbjct: 603 VCQYKAKVACVKSRDMHWALVAHKDQKDINLS-----LAAHAAG--SISSCDAFLNVFQT 655
Query: 125 KGVRGDAICPCACSSESMTVCIXXXXXXXXXX-XXXVLSMSGLSYGVVRVDAENSLTSLT 183
KG+R D ICPCA S E++TV I VLSM GL+YGVVRVD E L+ LT
Sbjct: 656 KGLRADVICPCASSPEALTVAIRRPVEDSSQPPGRGVLSMQGLTYGVVRVDTEERLSVLT 715
Query: 184 LQDCGQVMPSCVIVVVKMEGPAYLCKTDEVGEICVLSGATGSGYWGLPGLTNTVFRVRPL 243
+QD G V P ++ VVK EG LC+TDE+GE+CV S ATG+ Y+GL G+T F V P+
Sbjct: 716 VQDVGTVTPGGLVCVVKPEGLPQLCQTDEIGELCVCSIATGTSYYGLTGMTKNTFEVYPV 775
Query: 244 DSDGEPIGEEHYVRSXXXXXXXXXXXXXXXXSRDGLMTVTGRKHNMDDIIATVLAVEPMK 303
S G I + +VR+ DGL+ V+GR+HN DDI+AT LAVEPMK
Sbjct: 776 TSGGGLISDYAFVRTGLLGFIGPGGLVFITGKMDGLIMVSGRRHNADDIVATALAVEPMK 835
Query: 304 FIYRGRIAVFSVRVLRDERICIVAEQRPDCGEEESFQWMSRVLQAVDSIHQVGIYCLALV 363
F+YRGRIAVFSV VLRDERI +VAEQRPD EE+SFQWMSRVLQA+DSIH VG++CLALV
Sbjct: 836 FVYRGRIAVFSVTVLRDERIVVVAEQRPDSTEEDSFQWMSRVLQAIDSIHGVGVFCLALV 895
Query: 364 QPNFLPKTPLGGIHLSECKRRFLEGTLHPSNVLMCPHTCVTNLPKPREIHSDVGPASVIV 423
N LPKTPLGGIHLSE K+ +LEG LHP NVLMCPHTCVTNLPKPR+ ++G ASV+V
Sbjct: 896 PANTLPKTPLGGIHLSEIKQLYLEGGLHPCNVLMCPHTCVTNLPKPRQKQPEIGLASVMV 955
Query: 424 GNLVQGNRLASAQGRDMGYTDDSDAARKYQFISQILRWRAQSTSDHVIFTLLNAKGAVSK 483
GNLV G R+A A GRD+G TDD+D ++ F+S++L+WRAQ+T DHV++TLL+++GAVS
Sbjct: 956 GNLVSGKRIAQASGRDLGQTDDND---QFLFLSEVLQWRAQTTPDHVLYTLLSSRGAVSS 1012
Query: 484 VLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPP 543
LTC +LHK+AER+ LL+E+G + GDHVAL++PP C A P T+RPP
Sbjct: 1013 SLTCLQLHKRAERVAALLMERGGLQEGDHVALVYPPA----CT------PAASPSTVRPP 1062
Query: 544 HPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKK 603
HPQN+ TTLPTV+MIV+VS + V++ + KLLRSKEA +D + WP LDTDD+PK+
Sbjct: 1063 HPQNISTTLPTVKMIVEVSHSACVMTTAVICKLLRSKEAMATVDIRNWPPVLDTDDLPKR 1122
Query: 604 KLPIMYRAPTAEMLAYLDFSVSTTGMLAGI--------------------------KMSH 637
K P +Y+ + LAYLDFSVSTTGMLAG+ +M+H
Sbjct: 1123 KPPALYKPTNPDGLAYLDFSVSTTGMLAGVQVSSGSQSLPDAGAASSHLRRVCVCLQMTH 1182
Query: 638 AAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIPPSEVEVNP 697
AV + CRS+K+ CELYPSR +A+CLDPYCGLGF LWCL S+YSGH SILIPP E+E NP
Sbjct: 1183 NAVGAFCRSVKLQCELYPSREVAICLDPYCGLGFVLWCLCSVYSGHQSILIPPVELESNP 1242
Query: 698 ALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVVAEERPRIN 757
ALWL AVSQ +VRDTFCSY VMELCTKGLG LK++G++L+ VR CVVVAEERPR++
Sbjct: 1243 ALWLLAVSQLRVRDTFCSYSVMELCTKGLGLQTEALKARGLDLSRVRACVVVAEERPRMS 1302
Query: 758 LTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPSTVYVDLRALRNDRVSLVE 817
LT SFSKLF LGL PR+VST+FGCRVN+AICLQG S P+P+TVYVD+RALR+DRV LVE
Sbjct: 1303 LTYSFSKLFKDLGLHPRSVSTAFGCRVNLAICLQGTSGPDPTTVYVDMRALRHDRVRLVE 1362
Query: 818 RGSPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNASGYFTIYGDESD 877
+GSPHSL LMESGK+LPGV++I ANPETKG GDSHLGEIWV S HN SGY++ YG+E
Sbjct: 1363 KGSPHSLPLMESGKILPGVRIIIANPETKGPLGDSHLGEIWVHSAHNGSGYYSGYGEEVL 1422
Query: 878 YADHFSAQLVTGNTGEVYARTGYLGFLRRTEI 909
+DHF+++L G+T V+ARTGYLGFLRRTE+
Sbjct: 1423 QSDHFNSRLSFGDTQTVWARTGYLGFLRRTEL 1454
Score = 151 bits (366), Expect = 1e-34
Identities = 73/125 (58%), Positives = 83/125 (66%)
Query: 947 DTHDAVFVVGALDETIMLRGMRYHPIDIENSVMRCHKKIAECAVFTWTNLLVVVVELDGN 1006
+ HDA+FVVGAL+E + LRGMRYHPIDIE SV+R HK I ECAVFTWTNLLVVVVEL+G+
Sbjct: 1460 ERHDALFVVGALEEAMELRGMRYHPIDIETSVIRAHKSIMECAVFTWTNLLVVVVELEGS 1519
Query: 1007 DSEAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNSRGEKQRMHLRDGFLSDQIDAIY 1066
+ EA NSRGEKQRMHLRDGFL DQ+D IY
Sbjct: 1520 EQEALDLVPMVTKAVLEEHYLIVGVVVVTDIGVIPINSRGEKQRMHLRDGFLQDQLDPIY 1579
Query: 1067 IAYNM 1071
+AYNM
Sbjct: 1580 VAYNM 1584
Score = 58.0 bits (134), Expect = 1e-06
Identities = 109/532 (20%), Positives = 203/532 (38%), Gaps = 47/532 (8%)
Query: 473 TLLNAKGAVSKVLTCAELHKKAERIG-NLLLEKGR-----VNTGDHVALIFPPG--LDLI 524
T L+ G VLT +L ++ ++ N+L + G V GD VAL+FP + +
Sbjct: 333 TSLDTAGKPLYVLTYGKLWSRSIKLAYNILHKLGSKQEPMVRPGDRVALVFPNNDPVAFM 392
Query: 525 CAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASN 584
AFYGCL VPV I P + + ++ T+ L++ + K L
Sbjct: 393 VAFYGCLLAEVVPVPIEVPLSRK-DAGSQQIGFLLGSCGVTVALTSDACHKGLPKSATGE 451
Query: 585 VLDSKAWPMTL--DTDDMPKKKLP---IMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAA 639
+ K WP L T+ K P + AY+++ G + G+ ++ A
Sbjct: 452 IPQFKGWPKLLWFVTESKHLSKPPRDWFPHIKDANNDTAYIEYKTCKDGSVLGVTVTRIA 511
Query: 640 VTSLCRSMKIACE----LYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIPPSEVEV 695
+ + C+++ +C + + +C L S+ ++L +V +
Sbjct: 512 LLTHCQALTQSCSYTEGMRAHTNTHTHTHTFCSFNSRPLRL-SVAETVVNVLDFKKDVGL 570
Query: 696 NPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRT-----CVVVA 750
+ S ++ V Y +M++ V Q K+K +ACV++ +V
Sbjct: 571 WNGILTSVMNMMHVISV--PYSLMKVNPLSWIQKVCQYKAK---VACVKSRDMHWALVAH 625
Query: 751 EERPRINLT------------NSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGA---SS 795
+++ INL+ ++F +F GL + + + ++ SS
Sbjct: 626 KDQKDINLSLAAHAAGSISSCDAFLNVFQTKGLRADVICPCASSPEALTVAIRRPVEDSS 685
Query: 796 PEPSTVYVDLRALRNDRVSLVERGSPHSLCLMESGKLLPGVKVITANPETKGQ-CGDSHL 854
P + ++ L V + L + + G + PG V PE Q C +
Sbjct: 686 QPPGRGVLSMQGLTYGVVRVDTEERLSVLTVQDVGTVTPGGLVCVVKPEGLPQLCQTDEI 745
Query: 855 GEIWVQSPHNASGYFTIYGDESDYADHFSAQLVTGNTGE-VYARTGYLGFLRRTEIXXXX 913
GE+ V S + Y+ + G + + + G + + RTG LGF+ +
Sbjct: 746 GELCVCSIATGTSYYGLTGMTKNTFEVYPVTSGGGLISDYAFVRTGLLGFIGPGGLVFIT 805
Query: 914 XXXXXXXXMLPRDSDTDSLASACGSVSILPDSHDTHDAVFVVGAL-DETIML 964
+ R + D + + +V + + AVF V L DE I++
Sbjct: 806 GKMDGLIMVSGRRHNADDIVATALAVEPMKFVYRGRIAVFSVTVLRDERIVV 857
Score = 52.8 bits (121), Expect = 5e-05
Identities = 53/232 (22%), Positives = 94/232 (40%), Gaps = 10/232 (4%)
Query: 3 AHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLASVLNGMHVIFIPYALMKVSPASWM 62
A CR + + C + LD G L SV +G I IP ++ +PA W+
Sbjct: 1187 AFCRSVKLQCELYPSREVAICLDPYCGLGFVLWCLCSVYSGHQSILIPPVELESNPALWL 1246
Query: 63 HMITKHR-----ASIAIVKSRDLHWGL-LATRDHKEISLSSLRMLLVADGANPWSLSSCD 116
+++ R S ++++ GL + + LS +R +V P +S
Sbjct: 1247 LAVSQLRVRDTFCSYSVMELCTKGLGLQTEALKARGLDLSRVRACVVVAEERP-RMSLTY 1305
Query: 117 QFLSVFQSKGVRGDAICPCACSSESMTVCIXXXXXXXXXXXXXVLSMSGLSYGVVRVDAE 176
F +F+ G+ ++ ++ +C+ + M L + VR+ +
Sbjct: 1306 SFSKLFKDLGLHPRSVSTAFGCRVNLAICL--QGTSGPDPTTVYVDMRALRHDRVRLVEK 1363
Query: 177 NSLTSLTLQDCGQVMPSCVIVVVKMEGPAYLCKTDEVGEICVLSGATGSGYW 228
S SL L + G+++P I++ E L +GEI V S GSGY+
Sbjct: 1364 GSPHSLPLMESGKILPGVRIIIANPETKGPL-GDSHLGEIWVHSAHNGSGYY 1414
>UniRef50_Q1RS87 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 1539
Score = 1070 bits (2649), Expect = 0.0
Identities = 521/929 (56%), Positives = 665/929 (71%), Gaps = 28/929 (3%)
Query: 1 MLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLASVLNGMHVIFIPYALMKVSPAS 60
+ AHCR L+ A Y E E MVCV+DFKRE GLWHA+LAS+ NGM VIF+PY+LMK++PA+
Sbjct: 487 VFAHCRALTTAMEYKEDETMVCVVDFKREVGLWHAILASIFNGMKVIFVPYSLMKMNPAT 546
Query: 61 WMHMITKHRASIAIVKSRDLHWGLLATRDHKEISLSSLRMLLVADGANPWSLSSCDQFLS 120
WMHM++K++A+ A+VKSRDLHW LLATRDHK+ISL+SLR LLVADGANPWSLSSCD F +
Sbjct: 547 WMHMVSKYQATTALVKSRDLHWALLATRDHKDISLASLRTLLVADGANPWSLSSCDAFAA 606
Query: 121 VFQSK--GVRGDAICPCACSSESMTVCIXXXXXXXXXXXXX--VLSMSGLSYGVVRVDAE 176
F +R DA+CPCA SSE+ T+ I +LSMS LS+ VVRVD E
Sbjct: 607 AFTPSPYSLRPDAMCPCAGSSETGTISIRRRGNAQLGSQSGRGILSMSALSHCVVRVDTE 666
Query: 177 NSLTSLTLQDCGQVMPSCVIVVVKMEGPAYLCKTDEVGEICVLSGATGSGYWGLPGLTNT 236
NSLTSLTLQD GQ++ V+VV ++G LC+ DE+GEICV + +T YW L G T+
Sbjct: 667 NSLTSLTLQDAGQIVAGAVVVVTAIDGSNRLCQADEIGEICVSANSTAQLYWALDGQTHH 726
Query: 237 VFRVRPLDSDGEPIGEEHYVRSXXXXXXXXXXXXXXXXSRDGLMTVTGRKHNMDDIIATV 296
F+V P+ G+ IG YVRS R L+ V+GR H+ DDIIATV
Sbjct: 727 TFKVEPVGEYGKLIGAVRYVRSGLIGFMGPDGMVFVVARRQSLLAVSGRYHSADDIIATV 786
Query: 297 LAVEPMKFIYRGRIAVFSVRVLRDERICIVAEQRPDCGEEESFQWMSRVLQAVDSIHQVG 356
LAVEPMKF+YRGRI VFS VLRDERI IVAEQ+P+C EEE+F W++RVL+A+D+IHQVG
Sbjct: 787 LAVEPMKFVYRGRICVFSTSVLRDERIVIVAEQKPNCSEEEAFDWITRVLRAIDTIHQVG 846
Query: 357 IYCLALVQPNFLPKTPLGGIHLSECKRRFLEGTLHPSNVLMCPHTCVTNLPKPREIHSDV 416
IYC ALV N LPKTPLGG+H+SE K+RF G LHPS +LMCPH CV NLPKPRE +DV
Sbjct: 847 IYCCALVPANHLPKTPLGGVHVSETKQRFENGDLHPSTLLMCPHNCVLNLPKPRERQADV 906
Query: 417 GPASVIVGNLVQGNRLASAQGRDMGYTDDSDAARKYQFISQILRWRAQSTSDHVIFTLLN 476
GPA++ VGN+VQG R+A A+GR++ DD + + + LR RAQS+ DH I TL+
Sbjct: 907 GPAAMFVGNIVQGVRIAVAKGRNI---DDEPSLP----LLECLRSRAQSSPDHRILTLVT 959
Query: 477 AKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAV 536
+K A TC+ L K+AERI LL ++ R++ GDHVALIFPP +DL+ AF+GCL G V
Sbjct: 960 SKNAEQDTATCSTLLKRAERIAGLLTDRARLSRGDHVALIFPPSIDLVAAFFGCLSAGLV 1019
Query: 537 PVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLD 596
PV I+PP +L+TTL +RM+VD+SKA +L+ Q+V KLL+SKEA++ +DS AWPM LD
Sbjct: 1020 PVCIKPPVASDLNTTLGPIRMMVDMSKAVAILAPQNVSKLLKSKEAAHSIDSNAWPMILD 1079
Query: 597 TDDMP---KKK--------LPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCR 645
+D P ++K A + E + YLDFS++++G L G MS A+ ++C+
Sbjct: 1080 LEDAPSSWRRKNNNNCDTTTSGSSGAASKEEICYLDFSINSSGQLQGSSMSEASAITVCK 1139
Query: 646 SMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIPPSEVEVNPALWLSAVS 705
S+K++ ELYPSRH+ +C PY G+ LWCLSS+YSGHH+ LIPP EVE P+L+L+ +S
Sbjct: 1140 SIKVSSELYPSRHVVVCAPPYSGISLVLWCLSSVYSGHHTTLIPPMEVEQQPSLFLTTLS 1199
Query: 706 QYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVVAEERPRINLTNSFSKL 765
KVRD F +Y + C L +SV L+ +G NL+ +R+CV +AEERPRI L +SF KL
Sbjct: 1200 NLKVRDAFTTYSTINTCVTQLATSVENLRERGCNLSMLRSCVAIAEERPRIALMSSFCKL 1259
Query: 766 FSALGLSPRAVSTSFGCRVNIAICLQGASSPEPSTVYVDLRALRNDRVSLVERGSPHSLC 825
F+ L L+ RA+STSF RVN AIC+QGAS PEPSTVYVD RALRNDR+SLV +G+PHS+
Sbjct: 1260 FAPLALNNRAISTSFSSRVNAAICMQGASGPEPSTVYVDARALRNDRISLVGKGAPHSVA 1319
Query: 826 LMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNAS-----GYFTIYGDESDY-A 879
L+ESGKLLPGVK+ ANPET+GQC DSHLGEIWV S HNAS T +GDE
Sbjct: 1320 LIESGKLLPGVKIAIANPETRGQCADSHLGEIWVASIHNASPLNRLASVTGFGDEGTMNT 1379
Query: 880 DHFSAQLVTGNTGEVYARTGYLGFLRRTE 908
D ++A+L TG+T +ARTGYLGFLR+T+
Sbjct: 1380 DVYNARLTTGDTKTRWARTGYLGFLRQTQ 1408
Score = 99.1 bits (236), Expect = 6e-19
Identities = 46/125 (36%), Positives = 70/125 (56%)
Query: 947 DTHDAVFVVGALDETIMLRGMRYHPIDIENSVMRCHKKIAECAVFTWTNLLVVVVELDGN 1006
+ HDAVFVVGAL+E+++LRGMRYHP D+E++V + H+ + AVFTW +L+V+ E G+
Sbjct: 1415 ELHDAVFVVGALNESLVLRGMRYHPFDVESTVSKAHRFVGNSAVFTWNHLVVIAAECTGS 1474
Query: 1007 DSEAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNSRGEKQRMHLRDGFLSDQIDAIY 1066
+S+A GEK R +R FL ++++ IY
Sbjct: 1475 ESDALDLVPAITSAVLEEHHLIVGVVVVVDPGSIRHGPGGEKLRSTIRSLFLEEKLNPIY 1534
Query: 1067 IAYNM 1071
+AY+M
Sbjct: 1535 VAYHM 1539
Score = 96.7 bits (230), Expect = 3e-18
Identities = 121/489 (24%), Positives = 210/489 (42%), Gaps = 62/489 (12%)
Query: 465 STSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEK-------GRVNT----GDHV 513
+ + ++ +L+ S LT +LH +A ++ +LL K G N GD V
Sbjct: 279 TAAKNIAAMVLDQSAKPSTQLTYGKLHSRAGKVAYMLLTKTVQVNKDGSKNVMCKPGDRV 338
Query: 514 ALIFP--PGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQ 571
ALI+P L + AFYGCL G +PV + P + + + ++ + L+++
Sbjct: 339 ALIYPNTQPLHFLAAFYGCLQAGVIPVPVEMPSSKR-EAGIAQLGFLLGNCGVKVALTSE 397
Query: 572 SVIKLLRSK------------------EASNVLDSKAWPMT--LDTDDMPKKKLPIMYRA 611
S K L K +S ++D + WP T+ M K + A
Sbjct: 398 SCYKGLPKKVNTSSTFSAPSGSNSLTGTSSEIVDFRGWPRLWWAVTEHMSKPSRD--WTA 455
Query: 612 PTA---EMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCG 668
P E +AY++++ G + G ++ AV + CR++ A E + +D
Sbjct: 456 PPRLADETIAYIEYTTGNDGTVKGCCVTRQAVFAHCRALTTAMEYKEDETMVCVVDFKRE 515
Query: 669 LGFALWCLSSIYSGHHSILIPPSEVEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGS 728
+G L+SI++G I +P S +++NPA W+ VS+Y+ T +L L +
Sbjct: 516 VGLWHAILASIFNGMKVIFVPYSLMKMNPATWMHMVSKYQA--TTALVKSRDLHWALLAT 573
Query: 729 SVNQLKSKGINLACVRTCVVVAEERP-RINLTNSFSKLF--SALGLSPRAVSTSFGCRV- 784
K I+LA +RT +V P ++ ++F+ F S L P A+ G
Sbjct: 574 R----DHKDISLASLRTLLVADGANPWSLSSCDAFAAAFTPSPYSLRPDAMCPCAGSSET 629
Query: 785 -NIAICLQGAS--SPEPSTVYVDLRALRNDRVSLVERGSPHSLCLMESGKLLPG-VKVIT 840
I+I +G + + + + AL + V + S SL L ++G+++ G V V+T
Sbjct: 630 GTISIRRRGNAQLGSQSGRGILSMSALSHCVVRVDTENSLTSLTLQDAGQIVAGAVVVVT 689
Query: 841 ANPETKGQCGDSHLGEIWVQSPHNASGYFTIYGDESDYADHFSAQLVTGNTGEV-----Y 895
A + C +GEI V + A Y+ + G H G G++ Y
Sbjct: 690 AIDGSNRLCQADEIGEICVSANSTAQLYWALDGQ----THHTFKVEPVGEYGKLIGAVRY 745
Query: 896 ARTGYLGFL 904
R+G +GF+
Sbjct: 746 VRSGLIGFM 754
>UniRef50_Q4RQQ3 Cluster: Chromosome 2 SCAF15004, whole genome shotgun
sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 2
SCAF15004, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 1556
Score = 694 bits (1716), Expect = 0.0
Identities = 342/616 (55%), Positives = 428/616 (69%), Gaps = 23/616 (3%)
Query: 1 MLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLASVLNGMHVIFIPYALMKVSPAS 60
ML HC L+ AC YTEGE + VLDFKRE GLWH VL SV+N MHVI IPY+LMKV+P S
Sbjct: 583 MLTHCHTLTQACGYTEGETITNVLDFKREAGLWHGVLTSVMNRMHVISIPYSLMKVNPLS 642
Query: 61 WMHMITKHRASIAIVKSRDLHWGLLATRDHKEISLSSLRMLLVADGANPWSLSSCDQFLS 120
W+ + ++A +A+VKSRD+HW LLA RD ++ISL SLRML+VADGANPWS+SSCD FL+
Sbjct: 643 WIQKVHLYKARVAVVKSRDMHWSLLAQRDQRDISLGSLRMLIVADGANPWSISSCDAFLN 702
Query: 121 VFQSKGVRGDAICPCACSSESMTVCIXX-XXXXXXXXXXXVLSMSGLSYGVVRVDAENSL 179
VFQ++G+R + ICPCA SSE+MTV I VLSMSGLS+ V+RVD E L
Sbjct: 703 VFQARGLRPEVICPCASSSEAMTVAIRRPPEMDVPPPGKAVLSMSGLSHSVIRVDTEEKL 762
Query: 180 TSLTLQDCGQVMPSCVIVVVKMEGPAYLCKTDEVGEICVLSGATGSGYWGLPGLTNTVFR 239
+ LT+QD GQVMP V+ VV++EG YLC+TDEVGEICV SG+TG Y+GLPG+T +F
Sbjct: 763 SVLTVQDVGQVMPGAVVCVVRVEGTPYLCQTDEVGEICVSSGSTGVAYFGLPGMTKNIFE 822
Query: 240 VRPLDSDGEPIGEEHYVRSXXXXXXXXXXXXXXXXSRDGLMTVTGRKHNMDDIIATVLAV 299
PL S G PI + + R+ DGLM V+GR+HN DD++AT LAV
Sbjct: 823 TVPLLSSGAPISDRPFTRTSLLGFVGPDSLVFVVGKMDGLMVVSGRRHNADDVVATALAV 882
Query: 300 EPMKFIYRG----------------RIAVFSVRVLRDERICIVAEQRPDCGEEESFQWMS 343
EPMKF+YRG RIAVFSV VL DERI +VAEQRPD EE+SFQWMS
Sbjct: 883 EPMKFVYRGRRPEHTGAEQVDSQFFRIAVFSVSVLHDERIVVVAEQRPDASEEDSFQWMS 942
Query: 344 RVLQAVDSIHQVGIYCLALVQPNFLPKTPLGGIHLSECKRRFLEGTLHPSNVLMCPHTCV 403
RVLQA+DSIHQVG+YCLALV N LPK PLGGIH+SE K+RFLEG LHP NVLMCPHTCV
Sbjct: 943 RVLQAIDSIHQVGVYCLALVPANTLPKAPLGGIHISETKQRFLEGALHPCNVLMCPHTCV 1002
Query: 404 TNLPKPREIH-SDVGPASVI-VGNLVQGNRLASAQGRDMGYTDDSDAARKYQFISQILRW 461
TNLPKPR+ +G + + +++Q A+ + A + + + +
Sbjct: 1003 TNLPKPRQKQPGRLGSVPFLYIQDVLQWRAQATPDHPLFVVLNAKVAQCRADRLLETCKV 1062
Query: 462 RAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGL 521
S + F L +G V+ +C +LHK+AER+ L+ GR+NTGDHVAL++PPG+
Sbjct: 1063 SLIVESFCLFFCPL--QGTVASTASCLQLHKRAERVAAALM--GRLNTGDHVALVYPPGI 1118
Query: 522 DLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKE 581
DLI FYGCLY G VPVT+RPPHPQNL TTLPTV+MIV+VSK+ +L+ Q ++KLL+SK+
Sbjct: 1119 DLIATFYGCLYAGCVPVTVRPPHPQNLATTLPTVKMIVEVSKSVCILTTQGIMKLLKSKD 1178
Query: 582 ASNVLDSKAWPMTLDT 597
A+ +D K+WPM LDT
Sbjct: 1179 AAAAVDIKSWPMVLDT 1194
Score = 345 bits (848), Expect = 4e-93
Identities = 155/211 (73%), Positives = 185/211 (87%)
Query: 699 LWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVVAEERPRINL 758
LWL+AVSQ+KVR TFCSY VME+CTKGLGS L+ + +NL+CVRTC+VVAEERPRI+L
Sbjct: 1216 LWLAAVSQHKVRVTFCSYSVMEMCTKGLGSQTEALRLRNVNLSCVRTCMVVAEERPRISL 1275
Query: 759 TNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPSTVYVDLRALRNDRVSLVER 818
T SFSK+F LGLSPRAVST+ GCRVN+A+CLQG S P+P+TVYVD+RALR+DRV LVER
Sbjct: 1276 TQSFSKIFKDLGLSPRAVSTTLGCRVNVAVCLQGTSGPDPTTVYVDMRALRHDRVRLVER 1335
Query: 819 GSPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNASGYFTIYGDESDY 878
GSPHSL LMESGK+LPGVKVI ANPETKG GDSHLGE+WV SPHNA+GY+T+YG+E+ +
Sbjct: 1336 GSPHSLPLMESGKILPGVKVIIANPETKGPLGDSHLGEVWVSSPHNATGYYTVYGEEALH 1395
Query: 879 ADHFSAQLVTGNTGEVYARTGYLGFLRRTEI 909
ADHF+ +L G+T V+ARTGYLGFLRRTE+
Sbjct: 1396 ADHFNTKLSFGDTQTVWARTGYLGFLRRTEL 1426
Score = 155 bits (376), Expect = 6e-36
Identities = 75/127 (59%), Positives = 87/127 (68%)
Query: 945 SHDTHDAVFVVGALDETIMLRGMRYHPIDIENSVMRCHKKIAECAVFTWTNLLVVVVELD 1004
S + HDA++VVG+LDET+ LRGMRYHPIDIE SV+R HK IAECAVFTWTNLLVVVVEL+
Sbjct: 1430 SGERHDALYVVGSLDETLELRGMRYHPIDIETSVIRSHKSIAECAVFTWTNLLVVVVELE 1489
Query: 1005 GNDSEAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNSRGEKQRMHLRDGFLSDQIDA 1064
G++ EA NSRGEKQRMHLRDGFL+DQ+D
Sbjct: 1490 GSEQEALDLVALVTNVVLEEHYLIVGVVVVVDPGVIPINSRGEKQRMHLRDGFLADQLDP 1549
Query: 1065 IYIAYNM 1071
IY+AYNM
Sbjct: 1550 IYVAYNM 1556
Score = 117 bits (281), Expect = 2e-24
Identities = 117/466 (25%), Positives = 186/466 (39%), Gaps = 31/466 (6%)
Query: 460 RWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNT------GDHV 513
RW + L NA AV LT +L +++++ LL K GD V
Sbjct: 392 RWGTSQPKSPCLTALDNAGKAVY-TLTYGKLWTRSQKLAYTLLNKLSTRNEPLLVPGDRV 450
Query: 514 ALIFPPG--LDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQ 571
AL+FP + + AFYGCL VPV I P + + ++ TL L+
Sbjct: 451 ALVFPNNDPVMFMVAFYGCLLAELVPVPIEVPLTRK-DAGSQQIGFLLGSCGVTLALTTD 509
Query: 572 SVIKLLRSKEASNVLDSKAWPMTL--DTDDMPKKKLPIMYRAPTAEM---LAYLDFSVST 626
+ K L + V K WP L TD K P + P E +AY+++ S
Sbjct: 510 ACQKGLPKAQTGEVATFKGWPRLLWFVTDGKHVVKPPKDWHPPVREASNDVAYIEYKTSK 569
Query: 627 TGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSI 686
G G+ +SH+A+ + C ++ AC I LD G L+S+ + H I
Sbjct: 570 EGSTMGVTVSHSAMLTHCHTLTQACGYTEGETITNVLDFKREAGLWHGVLTSVMNRMHVI 629
Query: 687 LIPPSEVEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTC 746
IP S ++VNP W+ V YK R M S + Q + I+L +R
Sbjct: 630 SIPYSLMKVNPLSWIQKVHLYKARVAVVKSRDMH------WSLLAQRDQRDISLGSLRML 683
Query: 747 VVVAEERP-RINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASS---PEPSTVY 802
+V P I+ ++F +F A GL P + + + ++ P P
Sbjct: 684 IVADGANPWSISSCDAFLNVFQARGLRPEVICPCASSSEAMTVAIRRPPEMDVPPPGKAV 743
Query: 803 VDLRALRNDRVSLVERGSPHSLCLMESGKLLPGVKVITANPE-TKGQCGDSHLGEIWVQS 861
+ + L + + + L + + G+++PG V E T C +GEI V S
Sbjct: 744 LSMSGLSHSVIRVDTEEKLSVLTVQDVGQVMPGAVVCVVRVEGTPYLCQTDEVGEICVSS 803
Query: 862 PHNASGYFTIYGDESDYADHFSAQLVTGN---TGEVYARTGYLGFL 904
YF + G + + + L++ + + RT LGF+
Sbjct: 804 GSTGVAYFGLPGMTKNIFE--TVPLLSSGAPISDRPFTRTSLLGFV 847
>UniRef50_Q4SU65 Cluster: Chromosome undetermined SCAF14007, whole
genome shotgun sequence; n=2; Clupeocephala|Rep:
Chromosome undetermined SCAF14007, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 1449
Score = 592 bits (1461), Expect = e-167
Identities = 311/641 (48%), Positives = 406/641 (63%), Gaps = 82/641 (12%)
Query: 1 MLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLASVLNGMHVIFIPYALMKVSPAS 60
ML HC+ L+ +C+YTE E +V VLDFK++ GLWHAV SV+N +H+I +PYALMKV+P S
Sbjct: 529 MLTHCQALTQSCSYTEAETIVNVLDFKKDVGLWHAVQTSVMNMLHIISVPYALMKVNPLS 588
Query: 61 WMHMITKHRASIAIVKSRDLHWGLLATRDHKEISLSSLRMLLVADGANPWSLSSCDQFLS 120
W+ + +++A +A VKSRD+HW L+A RD ++++LSSLRMLLVADG+NPWS+SSCD FL+
Sbjct: 589 WIQKVCQYKAKVACVKSRDMHWALVAHRDQRDVNLSSLRMLLVADGSNPWSISSCDAFLN 648
Query: 121 VFQSKGVRGDAICPCACSSESMTVCIXXXXXXXXXX-XXXVLSMSGLSYGVVRVDAENSL 179
VFQSKG+R + ICPCA S E++TV I VLSM LS+GV+R+D+E L
Sbjct: 649 VFQSKGLRSEVICPCASSPEALTVAIRRPAEEGSAPPGRGVLSMQDLSHGVIRIDSEEKL 708
Query: 180 TSLTLQDCGQVMP------------------------SCVIVVVKMEGPAYLCKTDEVGE 215
+ LTLQD G VMP + ++ VK EG LCK DE+GE
Sbjct: 709 SVLTLQDVGSVMPGGEGATPVRPKRRQTSSVPLPPVFAALMCTVKAEGLPLLCKADEIGE 768
Query: 216 ICVLSGATGSGYWGLPGLTNTVFRVR-------------------------PLDSDGEPI 250
+ V + ATG+ Y+GLPG+T T+F V P + G PI
Sbjct: 769 LVVCTVATGTSYYGLPGMTKTMFEVSVRPFFCAFKVFAPFHSGVGLLLQVVPASNGGAPI 828
Query: 251 GEEHYVRSXXXXXXXXXXXXXXXXSRDGLMTVTGRKHNMDDIIATV-------------L 297
+ R+ DGLM V GR+H+ DDI+AT +
Sbjct: 829 SAAAFTRTGLLGFIGPAGLVFVAGKMDGLMAVGGRRHSADDIVATALAVEPMKFVYRGRI 888
Query: 298 AVEPMKFIYRGRIAVFSV---------------RVLR---DERICIVAEQRPDCGEEESF 339
AV + ++ RI V + RVL+ D+ I + P G
Sbjct: 889 AVFSVTVLHDERIVVVAEQRPDSTEEDSFQWMSRVLQVRTDQLIGAAGQLIPGSGFALFI 948
Query: 340 QWMSRVLQAVDSIHQVGIYCLALVQPNFLPKTPLGGIHLSECKRRFLEGTLHPSNVLMCP 399
+ +S QA+D IHQVG+YCLALV N LPKTPLGGIHLSE K+ FLEG LHP NVLMCP
Sbjct: 949 RLVSS-FQAIDGIHQVGVYCLALVPSNTLPKTPLGGIHLSETKQLFLEGALHPCNVLMCP 1007
Query: 400 HTCVTNLPKPREIHSDVGPASVIVGNLVQGNRLASAQGRDMGYTDDSDAARKYQFISQIL 459
HTCVTNLPKPR+ ++GPASV+VGNLV G R+A A GRD+G +D+D ARK+ F+S++L
Sbjct: 1008 HTCVTNLPKPRQKQPEIGPASVMVGNLVSGKRIAQASGRDLGQMEDNDQARKFLFLSEVL 1067
Query: 460 RWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPP 519
+WRAQ+T DHV++TLLNA+G V+ LTC +LHK+AE+I LL E+ + GDHVAL++PP
Sbjct: 1068 QWRAQTTPDHVLYTLLNARGTVAGSLTCLQLHKRAEKIAALLAERRHLQDGDHVALVYPP 1127
Query: 520 GLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVD 560
G+DLI AFYGCLY G VPVT+RPPHPQN+ TTLPTV+MIV+
Sbjct: 1128 GVDLIAAFYGCLYAGCVPVTVRPPHPQNIATTLPTVKMIVE 1168
Score = 402 bits (990), Expect = e-110
Identities = 190/281 (67%), Positives = 225/281 (80%), Gaps = 21/281 (7%)
Query: 598 DDMPKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSR 657
+D+PKKK P++++ ++ LAYLDFSVSTTGMLAG++MSH A ++ CRS+K+ CELYPSR
Sbjct: 1169 NDLPKKKPPLLFKPSNSDTLAYLDFSVSTTGMLAGVQMSHGATSAFCRSIKLQCELYPSR 1228
Query: 658 HIALCLDPYCGLGFALWCLSSIYSGHHSILIPPSEVEVNPALWLSAVSQYKVRDTFCSYG 717
+ALCLDPYCGLGF LWCL S+YSGH SILIPPSE+E NP+LWLSAVSQ +VRDTFCSY
Sbjct: 1229 EVALCLDPYCGLGFVLWCLCSVYSGHQSILIPPSELEANPSLWLSAVSQSRVRDTFCSYS 1288
Query: 718 VMELCTKGLGSSVNQLK---------------------SKGINLACVRTCVVVAEERPRI 756
VMELCTKGLG + LK ++G++L+ VRTCVVVAEERPR
Sbjct: 1289 VMELCTKGLGLQMEALKVGPREAPPLTDGWTLSLSAPQARGLDLSRVRTCVVVAEERPRT 1348
Query: 757 NLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPSTVYVDLRALRNDRVSLV 816
L SFSKLF LGL PRAVSTSFGCRVN+AICLQG S P+P+TVYVD+RALR+DRV LV
Sbjct: 1349 PLPQSFSKLFKDLGLPPRAVSTSFGCRVNLAICLQGTSGPDPTTVYVDMRALRHDRVRLV 1408
Query: 817 ERGSPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEI 857
ERGSPHSL LMESGK+LPGV++I ANPETKG G+SHLGE+
Sbjct: 1409 ERGSPHSLPLMESGKILPGVRIIIANPETKGPMGESHLGEV 1449
Score = 80.6 bits (190), Expect = 2e-13
Identities = 87/425 (20%), Positives = 172/425 (40%), Gaps = 29/425 (6%)
Query: 428 QGNRLASAQGRDMGYTDDSDAARKYQFISQILRWRAQSTSDHVIFTLLNAKGAVSKVLTC 487
+G ++ + QG +G + + + + + RW S + T ++ G LT
Sbjct: 310 EGAQMVAMQGEQLGVVTNWPPSLE----AALQRWGTISPKAPCL-TTMDTNGKPLYTLTY 364
Query: 488 AELHKKAERIG-NLLLEKGR-----VNTGDHVALIFPPG--LDLICAFYGCLYVGAVPVT 539
+L ++ ++ NLL + G V GD VAL++P + AFYGCL VPV
Sbjct: 365 GKLWSRSVKVAYNLLHKLGNKQEPLVRPGDRVALVYPNNDPAAFMTAFYGCLLAEVVPVP 424
Query: 540 IRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTL--DT 597
I P + + ++ + T+ L++ + K L + + WP L T
Sbjct: 425 IEVPLTRK-DAGSQQIGFLLGSCEVTVALTSDACQKGLPKSPTGEIPQFRGWPKVLWFVT 483
Query: 598 DDMPKKKLP---IMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELY 654
+ K P + AY+++ G + G+ ++ A+ + C+++ +C
Sbjct: 484 ESKHLSKPPRDWFPHIKDANRDTAYIEYKTCKDGSVLGVTVTRIAMLTHCQALTQSCSYT 543
Query: 655 PSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIPPSEVEVNPALWLSAVSQYKVRDTFC 714
+ I LD +G +S+ + H I +P + ++VNP W+ V QYK +
Sbjct: 544 EAETIVNVLDFKKDVGLWHAVQTSVMNMLHIISVPYALMKVNPLSWIQKVCQYKAKVACV 603
Query: 715 SYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVVAEERP-RINLTNSFSKLFSALGLSP 773
M + V + +NL+ +R +V P I+ ++F +F + GL
Sbjct: 604 KSRDMH------WALVAHRDQRDVNLSSLRMLLVADGSNPWSISSCDAFLNVFQSKGLRS 657
Query: 774 RAVSTSFGCRVNIAICLQGAS---SPEPSTVYVDLRALRNDRVSLVERGSPHSLCLMESG 830
+ + + ++ + S P + ++ L + + + L L + G
Sbjct: 658 EVICPCASSPEALTVAIRRPAEEGSAPPGRGVLSMQDLSHGVIRIDSEEKLSVLTLQDVG 717
Query: 831 KLLPG 835
++PG
Sbjct: 718 SVMPG 722
>UniRef50_Q86XV3 Cluster: DIP2C protein; n=2; Euteleostomi|Rep:
DIP2C protein - Homo sapiens (Human)
Length = 481
Score = 543 bits (1341), Expect = e-153
Identities = 248/349 (71%), Positives = 294/349 (84%)
Query: 561 VSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKKLPIMYRAPTAEMLAYL 620
VS++ +++ Q + KLLRS+EA+ +D + WP+ LDTDD+PKK+ + + + LAYL
Sbjct: 3 VSRSACLMTTQLICKLLRSREAAAAVDVRTWPLILDTDDLPKKRPAQICKPCNPDTLAYL 62
Query: 621 DFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIY 680
DFSVSTTGMLAG+KMSHAA ++ CRS+K+ CELYPSR +A+CLDPYCGLGF LWCL S+Y
Sbjct: 63 DFSVSTTGMLAGVKMSHAATSAFCRSIKLQCELYPSREVAICLDPYCGLGFVLWCLCSVY 122
Query: 681 SGHHSILIPPSEVEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINL 740
SGH SILIPPSE+E NPALWL AVSQYKVRDTFCSY VMELCTKGLGS LK++G++L
Sbjct: 123 SGHQSILIPPSELETNPALWLLAVSQYKVRDTFCSYSVMELCTKGLGSQTESLKARGLDL 182
Query: 741 ACVRTCVVVAEERPRINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPST 800
+ VRTCVVVAEERPRI LT SFSKLF LGL PRAVSTSFGCRVN+AICLQG S P+P+T
Sbjct: 183 SRVRTCVVVAEERPRIALTQSFSKLFKDLGLHPRAVSTSFGCRVNLAICLQGTSGPDPTT 242
Query: 801 VYVDLRALRNDRVSLVERGSPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQ 860
VYVD+RALR+DRV LVERGSPHSL LMESGK+LPGV++I ANPE KG GDSHLGEIWV
Sbjct: 243 VYVDMRALRHDRVRLVERGSPHSLPLMESGKILPGVRIIIANPEIKGPLGDSHLGEIWVH 302
Query: 861 SPHNASGYFTIYGDESDYADHFSAQLVTGNTGEVYARTGYLGFLRRTEI 909
S HNASGYFTIYGDES +DHF+++L G+T ++ARTGYLGFLRRTE+
Sbjct: 303 SAHNASGYFTIYGDESLQSDHFNSRLSFGDTQTIWARTGYLGFLRRTEL 351
Score = 153 bits (370), Expect = 3e-35
Identities = 73/125 (58%), Positives = 84/125 (67%)
Query: 947 DTHDAVFVVGALDETIMLRGMRYHPIDIENSVMRCHKKIAECAVFTWTNLLVVVVELDGN 1006
+ HDA++VVGALDE + LRGMRYHPIDIE SV+R HK + ECAVFTWTNLLVVVVELDG+
Sbjct: 357 ERHDALYVVGALDEAMELRGMRYHPIDIETSVIRAHKSVTECAVFTWTNLLVVVVELDGS 416
Query: 1007 DSEAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNSRGEKQRMHLRDGFLSDQIDAIY 1066
+ EA NSRGEKQRMHLRDGFL+DQ+D IY
Sbjct: 417 EQEALDLVPLVTNVVLEEHYLIVGVVVVVDIGVIPINSRGEKQRMHLRDGFLADQLDPIY 476
Query: 1067 IAYNM 1071
+AYNM
Sbjct: 477 VAYNM 481
Score = 51.6 bits (118), Expect = 1e-04
Identities = 52/236 (22%), Positives = 95/236 (40%), Gaps = 10/236 (4%)
Query: 3 AHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLASVLNGMHVIFIPYALMKVSPASWM 62
A CR + + C + LD G L SV +G I IP + ++ +PA W+
Sbjct: 84 AFCRSIKLQCELYPSREVAICLDPYCGLGFVLWCLCSVYSGHQSILIPPSELETNPALWL 143
Query: 63 HMITKH--RASIAIVKSRDLHWGLLATRDH----KEISLSSLRMLLVADGANPWSLSSCD 116
++++ R + +L L ++ + + LS +R +V P ++
Sbjct: 144 LAVSQYKVRDTFCSYSVMELCTKGLGSQTESLKARGLDLSRVRTCVVVAEERP-RIALTQ 202
Query: 117 QFLSVFQSKGVRGDAICPCACSSESMTVCIXXXXXXXXXXXXXVLSMSGLSYGVVRVDAE 176
F +F+ G+ A+ ++ +C+ + M L + VR+
Sbjct: 203 SFSKLFKDLGLHPRAVSTSFGCRVNLAICL--QGTSGPDPTTVYVDMRALRHDRVRLVER 260
Query: 177 NSLTSLTLQDCGQVMPSCVIVVVKMEGPAYLCKTDEVGEICVLSGATGSGYWGLPG 232
S SL L + G+++P I++ E L +GEI V S SGY+ + G
Sbjct: 261 GSPHSLPLMESGKILPGVRIIIANPEIKGPL-GDSHLGEIWVHSAHNASGYFTIYG 315
>UniRef50_Q4T6E9 Cluster: Chromosome undetermined SCAF8797, whole
genome shotgun sequence; n=2; Tetraodon nigroviridis|Rep:
Chromosome undetermined SCAF8797, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 1253
Score = 530 bits (1308), Expect = e-149
Identities = 249/397 (62%), Positives = 308/397 (77%), Gaps = 26/397 (6%)
Query: 462 RAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGL 521
RAQ+T +HV++TLL+++GAVS LTC +LHK+AER+ LL+E+G + GDHVAL++PPG+
Sbjct: 856 RAQNTPEHVLYTLLSSRGAVSSSLTCLQLHKRAERVAALLMERGGLQEGDHVALVYPPGI 915
Query: 522 DLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKE 581
DLI AFYG LY G VP+T+RPPHPQN+ TTLPTV+MIV+VS + V++ + KLLRSKE
Sbjct: 916 DLIAAFYGSLYAGCVPITVRPPHPQNISTTLPTVKMIVEVSHSACVMTTAVICKLLRSKE 975
Query: 582 ASNVLDSKAWPMTLDTDDMPKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIK------- 634
A +D + WP LDTDD+PK+K P +Y+ + LAYLDFSVSTTGMLAG++
Sbjct: 976 AMATVDIRNWPPVLDTDDLPKRKPPALYKPTNPDGLAYLDFSVSTTGMLAGVQVSSGSQS 1035
Query: 635 -------------------MSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWC 675
M+H AV + CRS+K+ CELYPSR +A+CLDPYCGLGF LWC
Sbjct: 1036 LPDAGAASSHLRRVCVCLQMTHNAVGAFCRSVKLQCELYPSREVAICLDPYCGLGFVLWC 1095
Query: 676 LSSIYSGHHSILIPPSEVEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKS 735
L S+YSGH SILIPP E+E NPALWL AVSQ +VRDTFCSY VMELCTKGLG LK+
Sbjct: 1096 LCSVYSGHQSILIPPVELESNPALWLLAVSQLRVRDTFCSYSVMELCTKGLGLQTEALKA 1155
Query: 736 KGINLACVRTCVVVAEERPRINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASS 795
+G++L+ VR CVVVAEERPR++LT SFSKLF LGL PR+VST+FGCRVN+AICLQG S
Sbjct: 1156 RGLDLSRVRACVVVAEERPRMSLTYSFSKLFKDLGLHPRSVSTAFGCRVNLAICLQGTSG 1215
Query: 796 PEPSTVYVDLRALRNDRVSLVERGSPHSLCLMESGKL 832
P+P+TVYVD+RALR+DRV LVE+GSPHSL LMESGK+
Sbjct: 1216 PDPTTVYVDMRALRHDRVRLVEKGSPHSLPLMESGKV 1252
Score = 483 bits (1191), Expect = e-134
Identities = 232/400 (58%), Positives = 290/400 (72%), Gaps = 6/400 (1%)
Query: 1 MLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLASVLNGMHVIFIPYALMKVSPAS 60
+L HC+ L+ +C+YTE E +V VLDFK++ GLW+ +L SV+N MHVI +PY+LMKV+P S
Sbjct: 443 LLTHCQALTQSCSYTEAETVVNVLDFKKDVGLWNGILTSVMNMMHVISVPYSLMKVNPLS 502
Query: 61 WMHMITKHRASIAIVKSRDLHWGLLATRDHKEISLSSLRMLLVADGANPWSLSSCDQFLS 120
W+ + +++A +A VKSRD+HW L+A +D K+I+LSSLRMLLVADG+NPWS+SSCD FL+
Sbjct: 503 WIQKVCQYKAKVACVKSRDMHWALVAHKDQKDINLSSLRMLLVADGSNPWSISSCDAFLN 562
Query: 121 VFQSKGVRGDAICPCACSSESMTVCIXXXXXXXXXX-XXXVLSMSGLSYGVVRVDAENSL 179
VFQ+KG+R D ICPCA S E++TV I VLSM GL+YGVVRVD E L
Sbjct: 563 VFQTKGLRADVICPCASSPEALTVAIRRPVEDSSQPPGRGVLSMQGLTYGVVRVDTEERL 622
Query: 180 TSLTLQDCGQVMPSCVIVVVKMEGPAYLCKTDEVGEICVLSGATGSGYWGLPGLTNTVFR 239
+ LT+QD G V + E LC+TDE+GE+CV S ATG+ Y+GL G+T F
Sbjct: 623 SVLTVQDVGTAG-----VCGETEALPQLCQTDEIGELCVCSIATGTSYYGLTGMTKNTFE 677
Query: 240 VRPLDSDGEPIGEEHYVRSXXXXXXXXXXXXXXXXSRDGLMTVTGRKHNMDDIIATVLAV 299
V P+ S G I + +VR+ DGL+ V+GR+HN DDI+AT LAV
Sbjct: 678 VYPVTSGGGLISDYAFVRTGLLGFIGPGGLVFITGKMDGLIMVSGRRHNADDIVATALAV 737
Query: 300 EPMKFIYRGRIAVFSVRVLRDERICIVAEQRPDCGEEESFQWMSRVLQAVDSIHQVGIYC 359
EPMKF+YRGRIAVFSV VLRDERI +VAEQRPD EE+SFQWMSRVLQA+DSIH VG++C
Sbjct: 738 EPMKFVYRGRIAVFSVTVLRDERIVVVAEQRPDSTEEDSFQWMSRVLQAIDSIHGVGVFC 797
Query: 360 LALVQPNFLPKTPLGGIHLSECKRRFLEGTLHPSNVLMCP 399
LALV N LPKTPLGGIHLSE K+ +LEG LHP NVLMCP
Sbjct: 798 LALVPANTLPKTPLGGIHLSEIKQLYLEGGLHPCNVLMCP 837
Score = 90.2 bits (214), Expect = 3e-16
Identities = 113/512 (22%), Positives = 202/512 (39%), Gaps = 32/512 (6%)
Query: 473 TLLNAKGAVSKVLTCAELHKKAERIG-NLLLEKGR-----VNTGDHVALIFPPG--LDLI 524
T L+ G VLT +L ++ ++ N+L + G V GD VAL+FP + +
Sbjct: 264 TSLDTAGKPLYVLTYGKLWSRSIKLAYNILHKLGSKQEPMVRPGDRVALVFPNNDPVAFM 323
Query: 525 CAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASN 584
AFYGCL VPV I P + + ++ T+ L++ + K L
Sbjct: 324 VAFYGCLLAEVVPVPIEVPLSRK-DAGSQQIGFLLGSCGVTVALTSDACHKGLPKSATGE 382
Query: 585 VLDSKAWPMTL--DTDDMPKKKLP---IMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAA 639
+ K WP L T+ K P + AY+++ TG + G+ ++ A
Sbjct: 383 IPQFKGWPKLLWFVTESKHLSKPPRDWFPHIKDANNDTAYIEYKTCKTGSVLGVTVTRIA 442
Query: 640 VTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIPPSEVEVNPAL 699
+ + C+++ +C + + LD +G L+S+ + H I +P S ++VNP
Sbjct: 443 LLTHCQALTQSCSYTEAETVVNVLDFKKDVGLWNGILTSVMNMMHVISVPYSLMKVNPLS 502
Query: 700 WLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVVAEERP-RINL 758
W+ V QYK + M + V K INL+ +R +V P I+
Sbjct: 503 WIQKVCQYKAKVACVKSRDMH------WALVAHKDQKDINLSSLRMLLVADGSNPWSISS 556
Query: 759 TNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGA---SSPEPSTVYVDLRALRNDRVSL 815
++F +F GL + + + ++ SS P + ++ L +
Sbjct: 557 CDAFLNVFQTKGLRADVICPCASSPEALTVAIRRPVEDSSQPPGRGVLSMQGL---TYGV 613
Query: 816 VERGSPHSLCLMESGKLLPGVKVITANPETKGQ-CGDSHLGEIWVQSPHNASGYFTIYGD 874
V + L ++ + G + E Q C +GE+ V S + Y+ + G
Sbjct: 614 VRVDTEERLSVLTVQDV--GTAGVCGETEALPQLCQTDEIGELCVCSIATGTSYYGLTGM 671
Query: 875 ESDYADHFSAQLVTGNTGE-VYARTGYLGFLRRTEIXXXXXXXXXXXXMLPRDSDTDSLA 933
+ + + G + + RTG LGF+ + + R + D +
Sbjct: 672 TKNTFEVYPVTSGGGLISDYAFVRTGLLGFIGPGGLVFITGKMDGLIMVSGRRHNADDIV 731
Query: 934 SACGSVSILPDSHDTHDAVFVVGAL-DETIML 964
+ +V + + AVF V L DE I++
Sbjct: 732 ATALAVEPMKFVYRGRIAVFSVTVLRDERIVV 763
Score = 35.5 bits (78), Expect = 7.8
Identities = 41/194 (21%), Positives = 76/194 (39%), Gaps = 9/194 (4%)
Query: 3 AHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLASVLNGMHVIFIPYALMKVSPASWM 62
A CR + + C + LD G L SV +G I IP ++ +PA W+
Sbjct: 1062 AFCRSVKLQCELYPSREVAICLDPYCGLGFVLWCLCSVYSGHQSILIPPVELESNPALWL 1121
Query: 63 HMITKHR-----ASIAIVKSRDLHWGL-LATRDHKEISLSSLRMLLVADGANPWSLSSCD 116
+++ R S ++++ GL + + LS +R +V P +S
Sbjct: 1122 LAVSQLRVRDTFCSYSVMELCTKGLGLQTEALKARGLDLSRVRACVVVAEERP-RMSLTY 1180
Query: 117 QFLSVFQSKGVRGDAICPCACSSESMTVCIXXXXXXXXXXXXXVLSMSGLSYGVVRVDAE 176
F +F+ G+ ++ ++ +C+ + M L + VR+ +
Sbjct: 1181 SFSKLFKDLGLHPRSVSTAFGCRVNLAICL--QGTSGPDPTTVYVDMRALRHDRVRLVEK 1238
Query: 177 NSLTSLTLQDCGQV 190
S SL L + G+V
Sbjct: 1239 GSPHSLPLMESGKV 1252
>UniRef50_UPI0000F1EC39 Cluster: PREDICTED: similar to KIAA0184
protein; n=1; Danio rerio|Rep: PREDICTED: similar to
KIAA0184 protein - Danio rerio
Length = 593
Score = 431 bits (1063), Expect = e-119
Identities = 215/365 (58%), Positives = 260/365 (71%), Gaps = 14/365 (3%)
Query: 111 SLSSCDQFLSVFQSKGVRGDAICPCACSSESMTVCIXXXXXXXXXX-XXXVLSMSGLSYG 169
S+SSCD FL+VFQS+G+R + ICPCA SSE++TV I VLSMSGLSYG
Sbjct: 92 SISSCDAFLNVFQSRGLRPEVICPCASSSEALTVAIRRPPETGVPPPGKAVLSMSGLSYG 151
Query: 170 VVRVDAENSLTSLTLQDCGQVMPSCVIVVVKMEGPAYLCKTDEVGEICVLSGATGSGYWG 229
V+RVD E L+ LT+QD GQVMP ++ V+++EG YLC+TDEVGEICV S TG Y+G
Sbjct: 152 VIRVDTEEKLSVLTVQDAGQVMPGGLVCVIRVEGTPYLCRTDEVGEICVSSSTTGISYYG 211
Query: 230 LPGLTNTVFRVRPLDSDGEPIGEEHYVRSXXXXXXXXXXXXXXXXSRDGLMTVTGRKHNM 289
LPG+T VF P+ S G PI + + R+ DGLM V+GR+HN
Sbjct: 212 LPGMTKNVFETIPVTSSGAPISDRAFTRTSLLGFIGPL---------DGLMVVSGRRHNA 262
Query: 290 DDIIATVLAVEPMKFIYRGRIAVFSVRVLRDERICIVAEQRPDCGEEESFQWMSRVLQAV 349
DD++AT LAVEPMKF+YRGRIAVFSV VL DERI +VAEQRPD EE+SFQWMSRVLQA+
Sbjct: 263 DDVVATALAVEPMKFVYRGRIAVFSVSVLHDERIVVVAEQRPDASEEDSFQWMSRVLQAI 322
Query: 350 DSIHQVGIYCLALVQPNFLPKTPLGGIHLSECKRRFLEGTLHPSNVLMCPHTCVTNLPKP 409
DSIHQVG+YCLALV N LPK PLGGIH+SE K+RFLEG LHP NVLMCPHTCVTNLPKP
Sbjct: 323 DSIHQVGVYCLALVPANTLPKAPLGGIHISESKQRFLEGALHPCNVLMCPHTCVTNLPKP 382
Query: 410 REIH--SDVGPASVIVGNLVQGNRLASAQGRDMGYTDDSDAARK-YQFISQILRWRAQ-S 465
R+ ++VGPAS+IVGNLV G R+A A GRD+ +D D K + ++ L R + +
Sbjct: 383 RQKQPGTEVGPASMIVGNLVAGKRIAQACGRDVTQLEDHDQLHKRAERVALALMERGRLN 442
Query: 466 TSDHV 470
DHV
Sbjct: 443 AGDHV 447
Score = 242 bits (593), Expect = 3e-62
Identities = 114/188 (60%), Positives = 142/188 (75%), Gaps = 19/188 (10%)
Query: 489 ELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNL 548
+LHK+AER+ L+E+GR+N GDHVAL++PPG+DLI FYGCLY G VPVT+RPPHPQNL
Sbjct: 423 QLHKRAERVALALMERGRLNAGDHVALLYPPGIDLIATFYGCLYAGCVPVTVRPPHPQNL 482
Query: 549 HTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKKLPIM 608
TTLPTV+MIV + ++ LR N T +D+P+K+LP +
Sbjct: 483 TTTLPTVKMIV-----------EKMLTDLRHIWTRN--------KTQTENDLPRKRLPQI 523
Query: 609 YRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCG 668
Y+ P+ EMLAYLDFSVSTTG+LAG+KMSHAA ++LCRS+K+ CELYPSR IA+CLDPYCG
Sbjct: 524 YKPPSPEMLAYLDFSVSTTGILAGVKMSHAATSALCRSIKLQCELYPSRQIAICLDPYCG 583
Query: 669 LGFALWCL 676
LGFALWCL
Sbjct: 584 LGFALWCL 591
>UniRef50_Q4SL77 Cluster: Chromosome undetermined SCAF14561, whole
genome shotgun sequence; n=6; Euteleostomi|Rep:
Chromosome undetermined SCAF14561, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 1291
Score = 330 bits (811), Expect = 1e-88
Identities = 160/254 (62%), Positives = 193/254 (75%), Gaps = 23/254 (9%)
Query: 559 VDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKKLPIMYRAPTAEMLA 618
+ VS++ ++++Q + KLLRSKEAS +D++ WP LDTDD+PKKK P++++ ++ LA
Sbjct: 1029 LQVSRSVCLMTSQILCKLLRSKEASAAVDARTWPPVLDTDDLPKKKPPLLFKPSNSDTLA 1088
Query: 619 YLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSS 678
YLDFSVSTTGMLAG MSH A ++ CRS+K+ CELYPSR +ALCLDPYCGLGF LWCL S
Sbjct: 1089 YLDFSVSTTGMLAG--MSHGATSAFCRSIKLQCELYPSREVALCLDPYCGLGFVLWCLCS 1146
Query: 679 IYSGHHSILIPPSEVEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLK---- 734
+YSGH SILIPPSE+E NP+LWLSAVSQ +VRDTFCSY VMELCTKGLG LK
Sbjct: 1147 VYSGHQSILIPPSELEANPSLWLSAVSQSRVRDTFCSYSVMELCTKGLGLQTEALKVGPR 1206
Query: 735 -----------------SKGINLACVRTCVVVAEERPRINLTNSFSKLFSALGLSPRAVS 777
++G++L+ VRTCVVVAEERPR LT SFSKLF LGL PRAVS
Sbjct: 1207 EAPPLTDGWTLSLSAPQARGLDLSRVRTCVVVAEERPRTALTQSFSKLFKDLGLHPRAVS 1266
Query: 778 TSFGCRVNIAICLQ 791
TSFGCRVN+AICLQ
Sbjct: 1267 TSFGCRVNLAICLQ 1280
Score = 211 bits (515), Expect = 9e-53
Identities = 89/146 (60%), Positives = 120/146 (82%)
Query: 1 MLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLASVLNGMHVIFIPYALMKVSPAS 60
ML HC+ L+ +C+YTE E +V VLDFK++ GLWHAV SV+N +H+I +PYALMKV+P S
Sbjct: 250 MLTHCQALTQSCSYTEAETIVNVLDFKKDVGLWHAVQTSVMNMLHIISVPYALMKVNPLS 309
Query: 61 WMHMITKHRASIAIVKSRDLHWGLLATRDHKEISLSSLRMLLVADGANPWSLSSCDQFLS 120
W+ + +++A +A VKSRD+HW L+A RD ++++LSSLRMLLVADG+NPWS+SSCD FL+
Sbjct: 310 WIQKVCQYKAKVACVKSRDMHWALVAHRDQRDVNLSSLRMLLVADGSNPWSISSCDAFLN 369
Query: 121 VFQSKGVRGDAICPCACSSESMTVCI 146
VFQSKG+R + ICPCA S E++TV I
Sbjct: 370 VFQSKGLRSEVICPCASSPEALTVAI 395
Score = 154 bits (374), Expect = 1e-35
Identities = 85/180 (47%), Positives = 104/180 (57%), Gaps = 25/180 (13%)
Query: 193 SCVIVVVKMEGPAYLCKTDEVGEICVLSGATGSGYWGLPGLTNTVFRVR----------- 241
+ ++ VK EG LCK DE+GE+ V + ATG+ Y+GLPG+T T+F V
Sbjct: 530 AALMCTVKAEGLPLLCKADEIGELVVCTVATGTSYYGLPGMTKTMFEVSVRPFFCAFKVF 589
Query: 242 --------------PLDSDGEPIGEEHYVRSXXXXXXXXXXXXXXXXSRDGLMTVTGRKH 287
P + G PI + R+ DGLM V GR+H
Sbjct: 590 APFHSGVGLLLQVVPASNGGAPISAAAFTRTGLLGFIGPAGLVFVAGKMDGLMAVGGRRH 649
Query: 288 NMDDIIATVLAVEPMKFIYRGRIAVFSVRVLRDERICIVAEQRPDCGEEESFQWMSRVLQ 347
+ DDI+AT LAVEPMKF+YRGRIAVFSV VL DERI +VAEQRPD EE+SFQWMSRVLQ
Sbjct: 650 SADDIVATALAVEPMKFVYRGRIAVFSVTVLHDERIVVVAEQRPDSTEEDSFQWMSRVLQ 709
Score = 126 bits (305), Expect = 2e-27
Identities = 60/122 (49%), Positives = 84/122 (68%), Gaps = 11/122 (9%)
Query: 399 PHTCVTNLPKPREIHSDVGPASVIVGNLVQGNRLASAQGRDMGYTDDSDAARKYQFISQI 458
P +T+ S++GPASV+VGNLV G R+A A GRD+G +D+D ARK+ F+S++
Sbjct: 819 PRPPLTSSSSSSSSSSEIGPASVMVGNLVSGKRIAQASGRDLGQMEDNDQARKFLFLSEV 878
Query: 459 LRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFP 518
L+WRAQ+T DHV++TLLNA+ LHK+AE+I LL E+ + GDHVAL++P
Sbjct: 879 LQWRAQTTPDHVLYTLLNAR-----------LHKRAEKIAALLAERRHLQDGDHVALVYP 927
Query: 519 PG 520
PG
Sbjct: 928 PG 929
Score = 77.8 bits (183), Expect = 1e-12
Identities = 79/363 (21%), Positives = 150/363 (41%), Gaps = 26/363 (7%)
Query: 428 QGNRLASAQGRDMGYTDDSDAARKYQFISQILRWRAQSTSDHVIFTLLNAKGAVSKVLTC 487
+G ++ + QG +G + + + + + RW S + T ++ G LT
Sbjct: 31 EGAQMVAMQGEQLGVVTNWPPSLE----AALQRWGTISPKAPCL-TTMDTNGKPLYTLTY 85
Query: 488 AELHKKAERIG-NLLLEKGR-----VNTGDHVALIFPPG--LDLICAFYGCLYVGAVPVT 539
+L ++ ++ NLL + G V GD VAL++P + AFYGCL VPV
Sbjct: 86 GKLWSRSVKVAYNLLHKLGNKQEPLVRPGDRVALVYPNNDPAAFMTAFYGCLLAEVVPVP 145
Query: 540 IRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTL--DT 597
I P + + ++ + T+ L++ + K L + + WP L T
Sbjct: 146 IEVPLTRK-DAGSQQIGFLLGSCEVTVALTSDACQKGLPKSPTGEIPQFRGWPKVLWFVT 204
Query: 598 DDMPKKKLP---IMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELY 654
+ K P + AY+++ G + G+ ++ A+ + C+++ +C
Sbjct: 205 ESKHLSKPPRDWFPHIKDANRDTAYIEYKTCKDGSVLGVTVTRIAMLTHCQALTQSCSYT 264
Query: 655 PSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIPPSEVEVNPALWLSAVSQYKVRDTFC 714
+ I LD +G +S+ + H I +P + ++VNP W+ V QYK +
Sbjct: 265 EAETIVNVLDFKKDVGLWHAVQTSVMNMLHIISVPYALMKVNPLSWIQKVCQYKAKVACV 324
Query: 715 SYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVVAEERP-RINLTNSFSKLFSALGLSP 773
M + V + +NL+ +R +V P I+ ++F +F + GL
Sbjct: 325 KSRDMH------WALVAHRDQRDVNLSSLRMLLVADGSNPWSISSCDAFLNVFQSKGLRS 378
Query: 774 RAV 776
+
Sbjct: 379 EVI 381
>UniRef50_Q4SNK5 Cluster: Chromosome 15 SCAF14542, whole genome
shotgun sequence; n=2; Tetraodon nigroviridis|Rep:
Chromosome 15 SCAF14542, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 676
Score = 247 bits (605), Expect = 1e-63
Identities = 111/176 (63%), Positives = 139/176 (78%), Gaps = 2/176 (1%)
Query: 559 VDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKKLPIMYRAPTAEMLA 618
+ VS++ ++++Q + KLLRSKEAS +D++ WP LDTDD+PKKK P++++ ++ LA
Sbjct: 240 LQVSRSVCLMTSQILWKLLRSKEASAAVDARTWPPVLDTDDLPKKKPPLLFKPSDSDTLA 299
Query: 619 YLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSS 678
YLDFSVSTTGMLAG MSH A ++ CRS+K+ CELYPSR +ALCL+P CGLGF LWCL S
Sbjct: 300 YLDFSVSTTGMLAG--MSHGATSAFCRSIKLQCELYPSREVALCLEPCCGLGFVLWCLCS 357
Query: 679 IYSGHHSILIPPSEVEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLK 734
+YSGH SILIPP E+E NP+LWLSAVSQ +VRD CSY VMELCTKGLG LK
Sbjct: 358 VYSGHQSILIPPPELEANPSLWLSAVSQSRVRDACCSYSVMELCTKGLGLQTGALK 413
Score = 138 bits (333), Expect = 1e-30
Identities = 66/106 (62%), Positives = 79/106 (74%)
Query: 804 DLRALRNDRVSLVERGSPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPH 863
D R V LVERGSPHSL LMESGK+LPGV +I ANPETKG G+SH GEIWV H
Sbjct: 524 DSGVTRQRWVRLVERGSPHSLPLMESGKILPGVGIIIANPETKGPMGESHPGEIWVHRGH 583
Query: 864 NASGYFTIYGDESDYADHFSAQLVTGNTGEVYARTGYLGFLRRTEI 909
NASGY T+ G E+ ++DHF ++L +T ++ARTGYLGFLRRTE+
Sbjct: 584 NASGYVTVDGHEALHSDHFCSRLSFRDTQTIWARTGYLGFLRRTEL 629
Score = 135 bits (326), Expect = 7e-30
Identities = 63/97 (64%), Positives = 76/97 (78%)
Query: 813 VSLVERGSPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNASGYFTIY 872
V LVERGS HSL LMESGK+LPGV +I ANPETKG G+SH GEIWV HNASGY T+
Sbjct: 2 VRLVERGSSHSLPLMESGKILPGVGIIIANPETKGPMGESHPGEIWVHRGHNASGYVTVD 61
Query: 873 GDESDYADHFSAQLVTGNTGEVYARTGYLGFLRRTEI 909
G E+ ++DHF ++L G+T ++ARTGYLGFLRR E+
Sbjct: 62 GHEALHSDHFCSRLSFGDTQTIWARTGYLGFLRRREL 98
Score = 58.0 bits (134), Expect = 1e-06
Identities = 25/43 (58%), Positives = 32/43 (74%)
Query: 945 SHDTHDAVFVVGALDETIMLRGMRYHPIDIENSVMRCHKKIAE 987
S + DA++VVGAL+E LRGMRYHP DIE S++R H+ I E
Sbjct: 633 SAERRDALYVVGALEEATELRGMRYHPTDIETSIIRTHESITE 675
Score = 53.2 bits (122), Expect = 4e-05
Identities = 23/37 (62%), Positives = 28/37 (75%)
Query: 951 AVFVVGALDETIMLRGMRYHPIDIENSVMRCHKKIAE 987
A++VVGAL+E LRGMRYHP DIE S +R H+ I E
Sbjct: 108 ALYVVGALEEATELRGMRYHPTDIETSTIRTHESITE 144
>UniRef50_Q4RQ07 Cluster: Chromosome 17 SCAF15006, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 17 SCAF15006, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 316
Score = 229 bits (561), Expect = 2e-58
Identities = 115/226 (50%), Positives = 152/226 (67%), Gaps = 19/226 (8%)
Query: 15 TEGEHMVCVLDFKRETGLWHAVLASVLNGMHVIFIPYALMKVSPASWMHMITKHRASIAI 74
T E +V VLD K++ GLWHAV SV+N +H+I +PYALMKV+P SW+ + +++A +A
Sbjct: 36 TAAETIVNVLDVKKDVGLWHAVQTSVMNMLHIISVPYALMKVNPLSWIQKVCQYKAKVAC 95
Query: 75 VKSRDLHWGLLATRDHKEISLSSLRMLLVADGANPWSLSSCDQFLSVFQSKGVRGDAICP 134
VKSRD+HW +A RD ++++LSSLRMLLVADG+NPWS+SSCD FL+VFQSKG+R P
Sbjct: 96 VKSRDMHWAPVAHRDQRDVNLSSLRMLLVADGSNPWSISSCDTFLNVFQSKGLR-----P 150
Query: 135 CACSSESMTVCIXXXXXXXXXXXXXVLSMSGLSYGVVRVDAENSLTSLTLQDCGQVMPSC 194
S VLS LS+GV+R+D+E L+ LTLQD G VMP
Sbjct: 151 AEEGS--------------APPGRGVLSTQDLSHGVIRIDSEEKLSVLTLQDVGSVMPGA 196
Query: 195 VIVVVKMEGPAYLCKTDEVGEICVLSGATGSGYWGLPGLTNTVFRV 240
++ VK EG LCK DE+GE+ V + ATG+ Y GLPG+T T+F V
Sbjct: 197 LMCTVKAEGLPLLCKADEIGELVVCTVATGTSYHGLPGMTKTMFEV 242
>UniRef50_UPI0001556409 Cluster: PREDICTED: similar to mKIAA1463
protein, partial; n=1; Ornithorhynchus anatinus|Rep:
PREDICTED: similar to mKIAA1463 protein, partial -
Ornithorhynchus anatinus
Length = 486
Score = 197 bits (480), Expect = 2e-48
Identities = 85/146 (58%), Positives = 114/146 (78%)
Query: 452 YQFISQILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGD 511
+QF++++L+WRAQ+T DHV+F LLNAKG +C +LHK+AERI L +KG +N GD
Sbjct: 1 HQFLAEVLQWRAQATPDHVLFLLLNAKGTTVCTASCLQLHKRAERIAATLGDKGHLNAGD 60
Query: 512 HVALIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQ 571
V L++PPG+DLI AFYGCLY G VPVT+RPPHPQNL TLPTVRMIVDVSKA +L+
Sbjct: 61 SVVLLYPPGIDLIAAFYGCLYAGCVPVTVRPPHPQNLTATLPTVRMIVDVSKAACILTTH 120
Query: 572 SVIKLLRSKEASNVLDSKAWPMTLDT 597
S+++LL+S+EA+ +D K P+ ++T
Sbjct: 121 SLLRLLKSREAAGAVDVKTCPIVINT 146
Score = 120 bits (289), Expect = 2e-25
Identities = 52/83 (62%), Positives = 68/83 (81%), Gaps = 1/83 (1%)
Query: 828 ESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNASGYFTIYGDESDYADHFSAQLV 887
ESG++LPGVKV+ NP+TKG GDSHLGE+WV SPH ASGY+TIY +E+ ADHF+ +L
Sbjct: 313 ESGEILPGVKVVIVNPDTKGPVGDSHLGEVWVNSPHTASGYYTIYDNETLQADHFNTRLS 372
Query: 888 TGNTGE-VYARTGYLGFLRRTEI 909
G+ + ++ARTGYLGF+RRTE+
Sbjct: 373 FGDAAQTLWARTGYLGFVRRTEL 395
Score = 71.3 bits (167), Expect = 1e-10
Identities = 31/46 (67%), Positives = 37/46 (80%)
Query: 945 SHDTHDAVFVVGALDETIMLRGMRYHPIDIENSVMRCHKKIAECAV 990
S + HDA++VVGALDET+ LRG+RYHP DIE SV R H+ IAEC V
Sbjct: 399 SGERHDALYVVGALDETLELRGLRYHPTDIETSVSRTHRSIAECQV 444
>UniRef50_Q5A8P6 Cluster: Acyl CoA ligase-like protein; n=6;
Saccharomycetales|Rep: Acyl CoA ligase-like protein -
Candida albicans (Yeast)
Length = 1600
Score = 186 bits (452), Expect = 4e-45
Identities = 164/682 (24%), Positives = 294/682 (43%), Gaps = 54/682 (7%)
Query: 353 HQVGIYCLALVQPNFLPKT-PLGGIHLSE--CKRRFLEGTLHPSNVLMCPHTCVTNLPKP 409
H + +YC+ +V + LPK GG ++ CK++FLEG+L V ++ +P
Sbjct: 793 HFLRLYCVVVVDCDTLPKLLRSGGREIANMLCKKKFLEGSLKADFVKFFIRKSISMIPHG 852
Query: 410 REIHSDV-GPASVIVGNLVQGN---RLASAQGRDMGYTDDSDAA-RKYQFISQILRWRAQ 464
++ + P + + N + ++ R+ D + A ++ I IL++R
Sbjct: 853 EDVIGGIWSPYVSELRSKALANFPDQYSTIDYREKSINDKTGAPLTDFKTIVDILKFRVA 912
Query: 465 STSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLI 524
+ D + F ++ + SK LT +L +A + L+EK + G +V L++ + +
Sbjct: 913 KSGDSIAFQNVD-NNSKSKPLTWKKLENRAYAVCQYLIEKANIKAGQYVILMYSLSEEFV 971
Query: 525 CAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRS----- 579
A Y CL G + V + P + P ++ + +L N V K L++
Sbjct: 972 IAVYACLMCGIIAVPMLPFDSNRIGEDFPAFVGVIRDFDISEILVNDEVEKFLKNGPIAD 1031
Query: 580 -------------KEASNVLDSKAWPMTLDTDDMPKKKLPIMYRAPTAEMLAYLDFSVST 626
K + V +K M + + + +R L +L+F+ +
Sbjct: 1032 SLKKITHKRVKSLKIKNTVKLTKVSNMASLNSKIASYQAEVNFRDENTTALVWLNFT--S 1089
Query: 627 TGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSI 686
G +S+ + +C+ K C L I C+ G+GF CL ++ G +
Sbjct: 1090 DHYRVGATLSNKNIIGVCKVFKETCNLSSQSAIIGCVRHTSGIGFLQACLLGVFLGTTTY 1149
Query: 687 LIPPSEVEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTC 746
L P NP + ++++KV+D F + +++ + + KG NL+ ++
Sbjct: 1150 LSSPVNYAENPLSFFLLLARHKVKDVFVTEQMLKY-------AAIKFTPKGFNLSNLKNM 1202
Query: 747 VVVAEERPRINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPSTVYVDLR 806
++ E R I+L +K+FS+ LS ++ST + N I + + P +Y+D
Sbjct: 1203 MISTENRVEIDLLRKIAKVFSSTKLSAASMSTVYNHYFNPMISSRSYMTVAPVDLYLDPI 1262
Query: 807 ALRNDRVSLVERGS-PHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNA 865
ALR VS+V + P++L + +SG + ++ NPET+ C + GEIWV S N
Sbjct: 1263 ALRQGYVSVVNQAEVPNALHIQDSGMVPVCTEIAIVNPETRKICKEGEFGEIWVCSEANL 1322
Query: 866 SGYFT-IYGDESDYAD-HFSAQLVTGNTGEVYARTGYLGFLRRTEIXXXXXXXXXXXXML 923
+ + G +A F + GN Y RTG LGFL I
Sbjct: 1323 TAFTNGPKGPVDHFAQTQFRGVIADGNPDVTYLRTGDLGFLYNVSITKN----------- 1371
Query: 924 PRDSDTDSLASACGSVSILPDSH-DTHDAVFVVGALDETIMLRGMRYHPIDIENSVMRCH 982
+ S+++ AS G D T +FV+G + +T + G+ + PIDIEN++ CH
Sbjct: 1372 -KSSNSNGGASGGGGGGGEADGEITTFQPLFVLGKIADTFEVMGLHHFPIDIENTIESCH 1430
Query: 983 KKIAE--CAVFTWTNLLVVVVE 1002
I +F + +VV E
Sbjct: 1431 SDIYRNGSCIFKCGDYTIVVCE 1452
Score = 81.4 bits (192), Expect = 1e-13
Identities = 118/511 (23%), Positives = 213/511 (41%), Gaps = 75/511 (14%)
Query: 458 ILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIF 517
IL +RA + + F +L+AKG ++ +L+ KA ++ + K + D V L++
Sbjct: 159 ILTYRANTYKSELAFIVLDAKGKEVSSISWEKLYLKAVKVAYEIQHKLTMKNSDSVVLLY 218
Query: 518 PPG--LDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIK 575
G + + A +GC G VT P H Q++ +L V I++++ L+L +++V K
Sbjct: 219 KDGEVTEFVVALFGCFMAG---VTAIPIH-QDI--SLTEVLNIINLTSTKLLLYSETVAK 272
Query: 576 LLRSKEASNVLDSKAWPMTL----DTDDMPKKKLPIMY-----------RAPTAEM---L 617
L N + WP L TD +K + + ++E L
Sbjct: 273 ELDRLSVQNSRIN--WPSKLLRWRTTDLGSARKSEVSHWNAKQQKLKKDNKTSSEQNTNL 330
Query: 618 AYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPS----------------RHIAL 661
AY++FS S G L GI +SH + + +A P+ + +
Sbjct: 331 AYVEFSRSPVGELRGIALSHRTIFHQMHCLDLALSSLPNSGGGLQRSYKQYRADKKVVLA 390
Query: 662 CLDPYCGLGFALWCLSSIYSGHHSILIPPSEVEVNPALWLSAVSQYKVRDTFCSYGVMEL 721
LD +G L L ++YSG+ I P +E+ L+ + +S+++ Y ++
Sbjct: 391 TLDIRFSIGIILGVLFTVYSGNVHIWAPQKVMEIQ-GLYANLISKWRASLLLADYFGLKR 449
Query: 722 CTKGLGSSVNQL----KSKGINLACVRTCVV------------VAEERPR-INLTNSFSK 764
T S + K++ ++L+ V+ +V +AE R + + +
Sbjct: 450 VTYDYQQSPSATRYFSKTQRVDLSSVKWALVNALTIDGEFMEILAERYLRPLGCQHPENA 509
Query: 765 LFSALGLSPR-----AVSTSFGCRVNIAICLQGASSPEPSTVYVDLRALRNDRVSLVERG 819
+ L LS ++ G + + + ++ S + S+V +D AL + V +VE
Sbjct: 510 IIPMLTLSEYGGMVISLRDWIGGKEKLGMSMKDDDSNDLSSVLIDKEALSRNIVKIVEIN 569
Query: 820 SP------HSLCLMES-GKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNASGYFTIY 872
H L +++ G LP + NPE+ LGEIW+ SP + G++ +
Sbjct: 570 PSANDDIGHDLLRVDAFGYPLPDATLAVVNPESSVLANKDELGEIWIDSPCLSGGFYGL- 628
Query: 873 GDESDYADHFSAQLVTGNTGEVYARTGYLGF 903
ES H + G + RTG LGF
Sbjct: 629 RKESKSIFHAKCRGSNGQLDMDFLRTGLLGF 659
Score = 37.1 bits (82), Expect = 2.6
Identities = 45/228 (19%), Positives = 80/228 (35%), Gaps = 6/228 (2%)
Query: 5 CRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLASVLNGMHVIFIPYALMKVSPASWMHM 64
C++ CN + ++ + G A L V G +P S+ +
Sbjct: 1107 CKVFKETCNLSSQSAIIGCVRHTSGIGFLQACLLGVFLGTTTYLSSPVNYAENPLSFFLL 1166
Query: 65 ITKHRASIAIVKSRDLHWGLLATRDHKEISLSSLRMLLVADGANPWSLSSCDQFLSVFQS 124
+ +H+ V + L + + K +LS+L+ ++++ N + + VF S
Sbjct: 1167 LARHKVKDVFVTEQMLKYAAIKFTP-KGFNLSNLKNMMIST-ENRVEIDLLRKIAKVFSS 1224
Query: 125 KGVRGDAICPCACSSESMTVCIXXXXXXXXXXXXXVLSMSGLSYGVVRVDAENSL-TSLT 183
+ A + I L L G V V + + +L
Sbjct: 1225 TKL--SAASMSTVYNHYFNPMISSRSYMTVAPVDLYLDPIALRQGYVSVVNQAEVPNALH 1282
Query: 184 LQDCGQVMPSCVIVVVKMEGPAYLCKTDEVGEICVLSGATGSGYWGLP 231
+QD G V P C + + +CK E GEI V S A + + P
Sbjct: 1283 IQDSGMV-PVCTEIAIVNPETRKICKEGEFGEIWVCSEANLTAFTNGP 1329
>UniRef50_A6QYH2 Cluster: Putative uncharacterized protein; n=1;
Ajellomyces capsulatus NAm1|Rep: Putative uncharacterized
protein - Ajellomyces capsulatus NAm1
Length = 1864
Score = 182 bits (444), Expect = 4e-44
Identities = 145/575 (25%), Positives = 251/575 (43%), Gaps = 34/575 (5%)
Query: 353 HQVGIYCLALVQPNFLPKTPLGG---IHLSECKRRFLEGTLHPSNVLMCPHTCVTNLPKP 409
H + ++C+ + PN LP+ G I C++ F G+L +V V NLP
Sbjct: 857 HHLRVFCIMITAPNTLPRVTKNGRQEIGNMLCRKEFDSGSLPCVHVKFGVERSVLNLPIG 916
Query: 410 RE----IHSDVGPASVIVGNLVQGNRLASAQGRDMGYTD-DSDAARKYQFISQILRWRAQ 464
+ I S A+ +Q + + RD+ D S + I +L+WR
Sbjct: 917 VDPVGGIWSPTSSAARQGALAMQDKQYSGVDYRDVVMDDRTSTPLNHFTTIFDLLQWRVT 976
Query: 465 STSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLI 524
++ + + ++ +G K +T + K + L K ++ GDHV L++ D +
Sbjct: 977 RQAEELSYCSIDGRGKEGKGITWKKFDTKVAGVAMYLRNKAKLKAGDHVILMYTHSEDFV 1036
Query: 525 CAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRS----- 579
A Y C +G + + + P L P +V + +L N V LL+
Sbjct: 1037 YAVYACFCLGVIALPMAPIDQNRLSEDAPAFLHLVADFRVRAILVNSDVNDLLKQKPIAQ 1096
Query: 580 --KEASNVLDSKAWPMTLDTDDMPKKKLPIMYRAPTA--EMLAYLDFSVST----TGMLA 631
K+++NVL P T +T PK+ + T E LA V T
Sbjct: 1097 HIKQSANVLRISI-PSTYNTARPPKQSHGCRHLGLTVQKEWLARQPALVWTYWTPDQRRM 1155
Query: 632 GIKMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIPPS 691
+ + H + +C+ K C++ SR + + GLGF CL +Y G + L P
Sbjct: 1156 SVHIGHDTIMGMCKVQKETCQMTSSRPVLGSVRSTIGLGFLHTCLMGVYVGAPTYLFSPV 1215
Query: 692 EVEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVVAE 751
+ NP A+++YK++DT Y ++ +GS + +KG L ++ ++ ++
Sbjct: 1216 DYATNPISLFLALARYKIKDT---YATSQMLDYAMGS----MAAKGFQLHELKNLMIASD 1268
Query: 752 ERPRINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPSTVYVDLRALRND 811
RPR ++ F+++ L A++T + +N I + EP + +D + LR
Sbjct: 1269 GRPRADIYQKIRLHFASVALDRTAINTIYSHVLNPMIVSRSYMCIEPIELCLDTKYLRQG 1328
Query: 812 RVSLVERGS-PHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNASGYFT 870
+ V+ S P+SL + +SG + ++ NPET GEIWVQS +A +
Sbjct: 1329 LIYPVDPDSEPNSLLVQDSGMVPVSTQIAIVNPETCCLAHVGEYGEIWVQSEASAKSF-- 1386
Query: 871 IYGDESDY-ADHFSAQLVTGNTGEVYARTGYLGFL 904
YG + ++ + F ++V G+ VY RTG LGFL
Sbjct: 1387 -YGTKQEFDLERFKGRVVDGDPSAVYVRTGDLGFL 1420
Score = 77.8 bits (183), Expect = 1e-12
Identities = 72/277 (25%), Positives = 128/277 (46%), Gaps = 31/277 (11%)
Query: 451 KYQFISQILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTG 510
++ + +LR RA++ + +L+ +G +T +L +AE++ ++ +K + G
Sbjct: 304 QFDNLPSVLRHRARTHPKQPAYWVLDQRGKEIASITWEKLGSRAEKVAQVIRDKSSLYRG 363
Query: 511 DHVALIF--PPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVL 568
D VAL++ ++ A GC G V V I NL P++ +I+ ++A L L
Sbjct: 364 DRVALVYRDTEVIEFAVAILGCFIAGVVAVPI-----NNLE-DYPSLNVILTSTQAHLAL 417
Query: 569 SNQSVIKLLRSKEASNVLDSKAWPMTLD---TDDM----PKKKLPIMYRAPTAEMLAYLD 621
+ ++ +K + + L WP ++ T++ PKKK A LAY++
Sbjct: 418 TTENNLKTFQRDITTQKL---TWPRGVEWWKTNEFGSYHPKKK--DESPALVVPDLAYIE 472
Query: 622 FSVSTTGMLAGIKMSHAAV--TSLCRSMKIACELYPSRHIA--------LCLDPYCGLGF 671
FS + TG L G+ MSH + C S +A +A LDP +G
Sbjct: 473 FSRAPTGDLRGVVMSHRTIMHQMTCLSAIVASASPDGTRLAKPHGETLISYLDPRQSIGM 532
Query: 672 ALWCLSSIYSGHHSILIPPSEVEVNPALWLSAVSQYK 708
L L +IY GH ++ + VE P L+ S +++Y+
Sbjct: 533 ILGILLTIYGGHTTVWLEARAVE-TPGLYASLITKYR 568
Score = 47.2 bits (107), Expect = 0.002
Identities = 19/54 (35%), Positives = 35/54 (64%), Gaps = 2/54 (3%)
Query: 952 VFVVGALDETIMLRGMRYHPIDIENSVMRCHKKIAE--CAVFTWTNLLVVVVEL 1003
+FV+G + ET + G+ + P+DIE ++ +CH+ + AVF NL+V ++E+
Sbjct: 1439 LFVLGGIGETFEINGLNHFPVDIETTIEKCHRNVVPGGSAVFQAGNLVVALIEV 1492
>UniRef50_A1D1R6 Cluster: AMP binding domain protein, putative; n=18;
Pezizomycotina|Rep: AMP binding domain protein, putative
- Neosartorya fischeri (strain ATCC 1020 / DSM 3700 /
NRRL 181)(Aspergillus fischerianus (strain ATCC 1020 /
DSM 3700 / NRRL 181))
Length = 1862
Score = 179 bits (435), Expect = 4e-43
Identities = 143/588 (24%), Positives = 256/588 (43%), Gaps = 41/588 (6%)
Query: 344 RVLQAVDSIHQVGIYCLALVQPNFLPKTPLGG---IHLSECKRRFLEGTLHPSNVLMCPH 400
R ++ + H + +YC+ L PN LP+ G I C++ F GTL +V
Sbjct: 924 RCMEVLYQEHHLRVYCVLLTAPNTLPRVTKNGRREIGNMLCRKEFDAGTLPCVHVKFGIE 983
Query: 401 TCVTNLPKPRE----IHSDVGPASVIVGNLVQGNRLASAQGRDMGYTD-DSDAARKYQFI 455
V NLP + I S + A+ +Q + + RD+ D S + I
Sbjct: 984 RSVMNLPVGVDPVGGIWSPLASATRQEMLAMQEKQYSGVDYRDVVMDDRTSTPLNNFATI 1043
Query: 456 SQILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVAL 515
+L+WR ++ + + ++ +G K +T + K + L K +V GDH+ L
Sbjct: 1044 VDLLQWRVSRQAEELAYCSIDGRGKEGKGITWKKFDLKVAAVAMYLKNKVKVRPGDHLIL 1103
Query: 516 IFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIK 575
++ D + A + C +G V + I P L P +++ K +L N V
Sbjct: 1104 MYTHSEDYVYAVHACFCLGVVVIPIAPIDQNRLAEDAPAFLHVINDFKVKAILVNSDVDH 1163
Query: 576 LLRSKEASNVLDSKAWPMTLDTDDMPKKKLPIMYRAPTAEMLAYLDFSVSTTGMLA---- 631
++R K S + A + + + P + + L F+V T + A
Sbjct: 1164 VMRQKIVSQHIKQSAQVLRIGVPAIYNTSKP----SKQSHGCRDLGFTVKETWLRADQPA 1219
Query: 632 -------------GIKMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSS 678
+++ H + +C+ K C++ SR + + GLGF L
Sbjct: 1220 LVWTYWTPDQRRISVQIGHDTILGMCKVQKETCQMTSSRPVLGSVRSTLGLGFLHTVLMG 1279
Query: 679 IYSGHHSILIPPSEVEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGI 738
IY G + L+ P + NP A+S+YK++DT+ + ++ L +++ + +KG
Sbjct: 1280 IYVGAPTYLVSPVDFAQNPMTLFVALSRYKIKDTYAT-------SQMLDYAMSVMPAKGF 1332
Query: 739 NLACVRTCVVVAEERPRINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEP 798
L ++ ++ AE RPR ++ F++ L A++ + +N + + EP
Sbjct: 1333 QLQEMKNLMISAEGRPRTDIYQKVRLHFASASLDRTAINIVYSHVLNPMVVTRSYMCIEP 1392
Query: 799 STVYVDLRALRNDRVSLVERGS-PHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEI 857
+++DLR+LR V V+ + P +L + +SG + +V NPET GEI
Sbjct: 1393 IELWLDLRSLRQGLVCPVDADTDPTALLVQDSGMVPVNTQVAIVNPETCTLSHVGEYGEI 1452
Query: 858 WVQSPHNASGYFTIYGDESDY-ADHFSAQLVTGNTGEVYARTGYLGFL 904
W+QS A + YG +++ A+ F+ ++V G+ Y RTG LGFL
Sbjct: 1453 WIQSDACAKAF---YGSRNEFDAERFNGRIVDGDPNVAYVRTGDLGFL 1497
Score = 76.6 bits (180), Expect = 3e-12
Identities = 77/302 (25%), Positives = 135/302 (44%), Gaps = 35/302 (11%)
Query: 430 NRLASAQGRDMGYT-----DDSDAARKYQFISQILRWRAQSTSDHVIFTLLNAKGAVSKV 484
N L + RD+ + D + + I +LR RA+ + +L+ KG
Sbjct: 259 NHLLPLEPRDIPFAVHDPHDKNTLMSNFDNIPAVLRHRARVHPKQPAYWVLDQKGKEIAS 318
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPG--LDLICAFYGCLYVGAVPVTIRP 542
+T +L +AE++ ++ +K + GD VALI+ ++ A GC G V V I
Sbjct: 319 ITWEKLASRAEKVAQVVRDKSNLYRGDRVALIYRDSEIIEFAVALMGCFIAGVVAVPI-- 376
Query: 543 PHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLD---TDD 599
NL ++ +++ ++A L L+ ++ +K S + + WP ++ T++
Sbjct: 377 ---NNLE-DYQSLNLVLTSTQAHLALTTENNLK---SFQRDITMQKLNWPRGVEWWKTNE 429
Query: 600 M----PKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAV--TSLCRSMKIAC-- 651
PK+K I A LAY++FS + TG + G+ MSH + C IA
Sbjct: 430 FGSYHPKRKDDI--PALVVPDLAYIEFSRAPTGDMRGVVMSHRTIMHQMACLGAIIATVP 487
Query: 652 ----ELYPSRHIALC-LDPYCGLGFALWCLSSIYSGHHSILIPPSEVEVNPALWLSAVSQ 706
+ P + LDP G+G L L ++Y GH ++ + VE P L+ V++
Sbjct: 488 GSGKSVRPHGETLISYLDPRQGIGMILGVLLTVYGGHTTVWLEDRAVE-TPGLYAHLVTK 546
Query: 707 YK 708
Y+
Sbjct: 547 YR 548
Score = 54.0 bits (124), Expect = 2e-05
Identities = 25/54 (46%), Positives = 36/54 (66%), Gaps = 2/54 (3%)
Query: 952 VFVVGALDETIMLRGMRYHPIDIENSVMRCHKKIAE--CAVFTWTNLLVVVVEL 1003
+FV+G + ET + G+ + P+DIENSV +CH+ I C VF L+VVVVE+
Sbjct: 1516 LFVLGGIGETFEVNGLNHFPMDIENSVEKCHRNIVPGGCCVFQAGGLIVVVVEV 1569
Score = 40.3 bits (90), Expect = 0.27
Identities = 22/63 (34%), Positives = 30/63 (47%), Gaps = 2/63 (3%)
Query: 188 GQVMPSCVIVVVKMEGPAYLCKTDEVGEICVLSGATGSGYWGLPGLTNTVFRVRPLD-SD 246
G +P + VV E LC + +GEI V S + G+W LP T +F RP +
Sbjct: 745 GYPIPDATLAVVDPE-TNLLCTPNVIGEIWVDSPSLSGGFWALPKHTEAIFHARPYKFEE 803
Query: 247 GEP 249
G P
Sbjct: 804 GNP 806
Score = 36.7 bits (81), Expect = 3.4
Identities = 22/84 (26%), Positives = 41/84 (48%), Gaps = 9/84 (10%)
Query: 797 EPSTVYVDLRALRNDRVSLVERGS---------PHSLCLMESGKLLPGVKVITANPETKG 847
E V +D AL+++ V ++ G P+++ + G +P + +PET
Sbjct: 703 ELGEVLLDKEALKSNEVVVLAMGEDARKYAATMPNAVRVGSFGYPIPDATLAVVDPETNL 762
Query: 848 QCGDSHLGEIWVQSPHNASGYFTI 871
C + +GEIWV SP + G++ +
Sbjct: 763 LCTPNVIGEIWVDSPSLSGGFWAL 786
>UniRef50_Q10250 Cluster: Uncharacterized protein C56F8.02; n=1;
Schizosaccharomyces pombe|Rep: Uncharacterized protein
C56F8.02 - Schizosaccharomyces pombe (Fission yeast)
Length = 1517
Score = 175 bits (427), Expect = 4e-42
Identities = 151/579 (26%), Positives = 245/579 (42%), Gaps = 35/579 (6%)
Query: 353 HQVGIYCLALVQPNFLPKTPLGG---IHLSECKRRFLEGTLHPSNVLMCPHTCVTNLPKP 409
HQV +YC+ + P LP+ G I C+R F GTL V V NLP
Sbjct: 778 HQVRVYCVLICAPFTLPRVTKNGRQEIGNMMCRRAFEHGTLPFLYVKFAVERAVLNLPVG 837
Query: 410 REIHSDVGP--ASVIVGNLVQGNRLASAQGRDMGYTDDSDAA---RKYQFISQILRWRAQ 464
+ + AS I NL+ L + D D+ + + Q+L+ R
Sbjct: 838 EDAIDGIWSSYASGIRQNLLSDQELQYSGFIDRSLRYDAKTSVDISSCHTMLQLLQLRVA 897
Query: 465 STSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLI 524
++ + + ++ +G K +T + ++ I L +K + G V L++ D +
Sbjct: 898 KNAEDIAYITIDGRGREGKNITWRKFDQRVATIIRYLQKKKYIKPGRVVVLMYTHSEDFV 957
Query: 525 CAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASN 584
A Y C Y+G +P+ + P L +P ++ + VL N LR+K S
Sbjct: 958 YALYACFYLGLIPIPVPPLDHMRLSEDVPAFLFLIKHYYVSAVLVNSEADTALRAKTTSQ 1017
Query: 585 VLDSKAW------PMTLDTDDMPKK---------KLPIMYRAPTAEMLAYLDFSVSTTGM 629
L A P + T + K+ KL + P L + +S
Sbjct: 1018 HLKQSAMAAKVVLPSFIVTSKISKQTKSIKELNVKLDPICLDPAFPALVWAFWSPDHRLT 1077
Query: 630 LAGIKMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIP 689
L +H + S+C+ K C++ R + + G+GF CL ++ G + L+
Sbjct: 1078 LTAY--NHQTLLSICQIHKETCQMTHKRPLLGHVRSMSGIGFFHTCLMGVFLGTTTYLLS 1135
Query: 690 PSEVEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVV 749
P + NP L +S+YK++DT+ ++ + L NQ +K NL+C+ ++
Sbjct: 1136 PVDFANNPLLLFQIISKYKIKDTYATF-------QTLNYIQNQQPTKWPNLSCLENLMIP 1188
Query: 750 AEERPRINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPSTVYVDLRALR 809
+ R S K F GLSP A ST + +N I + P+ +DLRALR
Sbjct: 1189 HDGRISAFYIASLQKYFVKHGLSPYAFSTVYSNCLNPFISTRSYMGAIPTPQLLDLRALR 1248
Query: 810 NDRVSLVERG-SPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNASGY 868
+ + E P++L L++SG + ++ NP+T+ C GEIW++S NA +
Sbjct: 1249 HGLIQPCESADKPYALPLLDSGMVPVSTQLAIVNPDTRELCRVGEYGEIWMRSSANAISF 1308
Query: 869 FTIYGDESDYADHFSAQLVTGNTGEVYARTGYLGFLRRT 907
F D D F+A G G Y RTG LGFL+ T
Sbjct: 1309 FQ-STDPVDMM-RFNATNSDGFLGNGYVRTGDLGFLQIT 1345
Score = 78.2 bits (184), Expect = 1e-12
Identities = 118/533 (22%), Positives = 220/533 (41%), Gaps = 89/533 (16%)
Query: 450 RKYQFISQILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNT 509
+++ I+ +LR+R ++ F +L+ KG +T +L +AE++ ++ +K +
Sbjct: 159 KQFTNIAAVLRYRGVHSAKKTAFIILDNKGKEFTSITWEKLASRAEKVAQVIRDKSGLFR 218
Query: 510 GDHVALIFP--PGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLV 567
D V L++ +D + + +GC G V V P N + I+ + A L
Sbjct: 219 SDRVVLMYRDCEAIDFVVSLFGCFIAGVVAV------PINRFDDYNELSSILTTTSARLA 272
Query: 568 LSNQSVIKLLRSKEASNVLDSKAWPMTLD---TDDMPKKKLPIMYRAPTAEM--LAYLDF 622
L+ + +K + + L WP ++ T++ L P ++ LAY++F
Sbjct: 273 LTTDANLKAFQRDLNAKKLH---WPKNVEWWKTNEFGGFHLKKKAEMPPLQVPDLAYIEF 329
Query: 623 SVSTTGMLAGIKMSHAAV---TSLCRSMKIACELYPSRHI-------------------A 660
S S G L G+ +SH + + ++ Y S +
Sbjct: 330 SRSPIGELHGVVISHRTILHQMNCLAAIHATAPAYESDKLDYLSIDREYTEGLSKSGLFL 389
Query: 661 LCLDPYCGLGFALWCLSSIYSGHHSILIPPSEVEVNPALWLSAVSQYKVRDTFCSYGVME 720
LD +G L L +++SG+ ++ P + V V P LW + ++Y+ Y ++
Sbjct: 390 TYLDLRQAIGLILGVLHTVFSGYTTVWCPQNAVFV-PGLWANLATRYRASFMLTDYAGLK 448
Query: 721 LCTKGL----GSSVNQLKSKGINLACVRTCVVVAEERPRINLTNSFSKLFS-----ALG- 770
+++ K ++L+ +R C+V +N+ F ++ S LG
Sbjct: 449 TIAYNYQNDPKATLGFSKKHSVDLSSLRMCMVDC-----LNVDCEFQEIVSDRWLKPLGN 503
Query: 771 LSPRAVSTSFGC---RVNIAICL------------QGASSP-----EPSTVYVDLRALR- 809
+PRA C + I + +G SP E S V ++ AL+
Sbjct: 504 QNPRATFVPLLCLPEHGGMVISMKDWIGGEEFMSPKGFKSPRTPENEISEVLLEKEALKL 563
Query: 810 NDRVSLVE-----RGSPHSLCLMESGKLLPGVKVITA--NPETKGQCGDSHLGEIWVQSP 862
N+ V L E R S H + P V A +PET+ C + +GEIWV SP
Sbjct: 564 NEVVVLAEDDKARRQSKHPNTIRVGAFWYPFVDATLAIVDPETQVLCLPNIVGEIWVDSP 623
Query: 863 HNASGYFTIYGDESDYADHFSAQLVTGNT------GEVYARTGYLGFLRRTEI 909
+ G+F + +++ H ++ +T + + RTG LGF+R+ ++
Sbjct: 624 SLSGGFFAL-PKQTEAIFHARTSFISSDTFQPIPSNQEFLRTGLLGFIRKGKV 675
Score = 43.6 bits (98), Expect = 0.029
Identities = 22/58 (37%), Positives = 35/58 (60%), Gaps = 2/58 (3%)
Query: 952 VFVVGALDETIMLRGMRYHPIDIENSVMRCHKKIAE--CAVFTWTNLLVVVVELDGND 1007
++V+G + ET + G+ + P DIE+++ R H +IA AVF +VVV+E G D
Sbjct: 1361 LYVLGPIGETFEVNGLSHFPSDIEDTIERSHPRIARGGTAVFQSAGRVVVVIEALGQD 1418
>UniRef50_Q4SNK2 Cluster: Chromosome 15 SCAF14542, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 15 SCAF14542, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 294
Score = 175 bits (425), Expect = 7e-42
Identities = 77/126 (61%), Positives = 102/126 (80%), Gaps = 2/126 (1%)
Query: 557 MIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKKLPIMYRAPTAEM 616
MIV+VS++ ++++Q + KLLRSKEAS +D++ WP LDTDD+PKKK P++++ ++
Sbjct: 1 MIVEVSRSVCLMTSQILWKLLRSKEASAAVDARTWPPVLDTDDLPKKKPPLLFKPSDSDT 60
Query: 617 LAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCL 676
LAYLDFSVSTTGMLAG MSH A ++ CRS+K+ CELYPSR +ALCL+P CGLGF LWCL
Sbjct: 61 LAYLDFSVSTTGMLAG--MSHGATSAFCRSIKLQCELYPSREVALCLEPCCGLGFVLWCL 118
Query: 677 SSIYSG 682
S+YSG
Sbjct: 119 CSVYSG 124
>UniRef50_Q6CA71 Cluster: Similar to tr|Q9C3Z2 Cochliobolus
heterostrophus Peptide synthetase- like protein; n=1;
Yarrowia lipolytica|Rep: Similar to tr|Q9C3Z2
Cochliobolus heterostrophus Peptide synthetase- like
protein - Yarrowia lipolytica (Candida lipolytica)
Length = 1455
Score = 173 bits (422), Expect = 2e-41
Identities = 139/580 (23%), Positives = 254/580 (43%), Gaps = 38/580 (6%)
Query: 353 HQVGIYCLALVQPNFLPKTPLGG---IHLSECKRRFLEGTLHPSNVLMCPHTCVTNLPKP 409
H+V ++C+ + P+ LP+T G I CKRRF +G L + +P
Sbjct: 734 HKVRVFCVLITAPHTLPRTMKNGRSEIGNMLCKRRFSQGLLPAVYCKFGIIQALKTIPCG 793
Query: 410 REIHSDVGPASV--IVGNLV--QGNRLASAQGRDMGYTD-DSDAARKYQFISQILRWRAQ 464
++ + +++ I + + + + + RD+ D S + + +IL+WR
Sbjct: 794 QDPEGGIWSSAISHIRSDYLGMADKQYSGIELRDVVRDDRTSTPLSAFGSLVEILQWRVA 853
Query: 465 STSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLI 524
+D + ++ + G K L+ + ++ + + L K + GDH L++ D +
Sbjct: 854 HQADELAYSTIQQSGKEGKALSWKKFDQRVSTVCHYLKNKVGLKQGDHALLLYTHSEDFV 913
Query: 525 CAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASN 584
A Y C+ +G V V + P LH +P ++ K +L N +++K S
Sbjct: 914 VAVYACMALGIVAVPLPPLDSGRLHEDIPAYCGVISEYKIKAILVNSETETSMKAKLISQ 973
Query: 585 VLDSKAWPMTLDTDDMPKKKLPIMYRAPTAEML-----------AYLDFSVSTTGMLAGI 633
A + + P + + T ++ A + + S +G+
Sbjct: 974 QSKQIAAQLKVVLPKKYNTSKPKLAHSGTRDLRYIVKPEDTNRPAVVWLTWSAEHRRSGV 1033
Query: 634 KMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIPPSEV 693
++H + +C+ K C++ ++ + C+ G+GF C +Y G + L+ P +
Sbjct: 1034 MLTHRTLMGMCKVQKETCQMASTKPVVGCVRSTSGIGFLHTCALGVYLGASTYLVSPIDY 1093
Query: 694 EVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVVAEER 753
VNP A S+YKV+D + + +++ + LK KG +LA ++ + R
Sbjct: 1094 TVNPLTLFLAYSRYKVKDVYSTPQMLDY-------ACATLKPKGFSLAETLNLMIAYDGR 1146
Query: 754 PRINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPSTVYVDLRALRNDRV 813
PR++L + LF + LS A+S+ + +N + + EP +++D ALR +
Sbjct: 1147 PRVDLAKNLRMLFLSTQLSNTAISSLYCHTLNPMVASRSYMGLEPIDLWLDPIALRQGYI 1206
Query: 814 SLVE-RGSPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNASGYFTIY 872
S+V P++L + +SG + G ++ NPET+ C GEIWV S N +
Sbjct: 1207 SVVNPENYPNALHVHDSGMVPVGTRIAIVNPETRQLCKVGEFGEIWVWSEGNVQQAYPA- 1265
Query: 873 GDESDYA--------DHFSAQLVTGNTGEVYARTGYLGFL 904
DE D A D AQ +T G+ Y RTG LGFL
Sbjct: 1266 RDEFDRARFQGKLDDDSNEAQAIT-RQGD-YVRTGDLGFL 1303
Score = 93.1 bits (221), Expect = 4e-17
Identities = 90/328 (27%), Positives = 151/328 (46%), Gaps = 36/328 (10%)
Query: 448 AARKYQFISQILRWRAQSTSDHV-IFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGR 506
A K+ + ILR RA++ + H I TL +AKG V+T +L KAER+ ++ +K
Sbjct: 106 AMAKFDNLPSILRHRAKTNAAHTAIITLDDAKGKDVNVITWEKLASKAERVAQMIRDKSN 165
Query: 507 VNTGDHVALIFPPG--LDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKA 564
+ D VAL++ ++ A GC G V V I P + H ++ ++
Sbjct: 166 LYRADRVALLYQDSEVVEFAVAILGCFLAGVVAVPINPFY----H--FKDTTYVMHTTQI 219
Query: 565 TLVLSNQSVIKLLRSKEASNVLDSKAWPMTLD---TDDMPKKKLPIMY-RAPTAEM--LA 618
L L+ + K++ V D + WP ++ T++ + P + P ++ LA
Sbjct: 220 HLALTTEVTYKIVHK---HMVQDRQQWPKGVEWWKTNEFGSYQKPSKHAEMPALQVPDLA 276
Query: 619 YLDFSVSTTGMLAGIKMSHAAV----TSLCRSMKIACE-LYPSRH------IALCLDPYC 667
Y++FS S TG L G+ MSH + T L +K + + P I LD
Sbjct: 277 YIEFSRSPTGDLRGVVMSHRTIIHQMTCLTAMLKSRDKFVQPDNRYQRGDVILSSLDSRQ 336
Query: 668 GLGFALWCLSSIYSGHHSILIPPSEVEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLG 727
+G + L ++Y+G + IP S + V P L+ +A+S++KV Y ++
Sbjct: 337 SIGLIMGVLLTVYTGSTLVWIPHSALAV-PGLYANAISRHKVTILLSDYPALKQVAYNY- 394
Query: 728 SSVNQL-----KSKGINLACVRTCVVVA 750
S QL K + +NLA V+ C++ A
Sbjct: 395 QSFPQLTRAYSKKQQVNLASVKWCLIDA 422
Score = 49.2 bits (112), Expect = 6e-04
Identities = 41/148 (27%), Positives = 63/148 (42%), Gaps = 7/148 (4%)
Query: 797 EPSTVYVDLRALRNDRVSLVE--RGSPHSLCLMESGKL---LPGVKVITANPETKGQCGD 851
E S + +D +L + + L+ RG SL + G LP + NPET+
Sbjct: 495 ELSKILLDKPSLTTNNIRLIPPVRGGEDSLKHIRVGAFGYPLPDSTLAIVNPETRKLLPK 554
Query: 852 SHLGEIWVQSPHNASGYFTIYGDESDYADHFSAQLVTGNTGEVYARTGYLGFLRRTEIXX 911
+GEIW+ SP + G++ + G E+D H +G + RTG LGF+ ++
Sbjct: 555 MVVGEIWIDSPCLSGGFWGM-GPETDMVFHARCYGNSGMLDLEFLRTGLLGFIYGGKVYV 613
Query: 912 XXXXXXXXXXML-PRDSDTDSLASACGS 938
P D D D+ A A S
Sbjct: 614 LGLYEDRLRQRYDPADEDADATAGAGSS 641
>UniRef50_Q2UQJ0 Cluster: Predicted AMP-binding protein; n=6;
Pezizomycotina|Rep: Predicted AMP-binding protein -
Aspergillus oryzae
Length = 1717
Score = 173 bits (420), Expect = 3e-41
Identities = 136/586 (23%), Positives = 247/586 (42%), Gaps = 37/586 (6%)
Query: 344 RVLQAVDSIHQVGIYCLALVQPNFLPKTPLGG---IHLSECKRRFLEGTLHPSNVLMCPH 400
R ++ + H + +YC+ L PN LP+ G I C+R F GTL +V
Sbjct: 768 RCMEVLYQEHHLRVYCVLLTAPNTLPRVTKNGRREIGNMLCRRDFDSGTLPCVHVKFGVE 827
Query: 401 TCVTNLPKPREIHSDVGPASVIVGN----LVQGNRLASAQGRDMGYTD-DSDAARKYQFI 455
V NLP + + ++ +Q + + R++ D S + I
Sbjct: 828 RSVMNLPVGVDPVGGIWSPLALMSRQEMLAMQEKQYSGVDYREVVMDDRTSTPLSNFSTI 887
Query: 456 SQILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVAL 515
+L WR ++ + + ++ +G K +T + K + L K +V GDH+ L
Sbjct: 888 VDLLHWRVSRQAEELAYCSIDGRGKEGKGITWKKFDLKVAAVATYLRNKVKVRPGDHLVL 947
Query: 516 IFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIK 575
++ + + A + C +G V + + P L P +++ ++ N V
Sbjct: 948 MYTHSEEYVYAVHACFCLGVVAIPLPPIDQNRLSEDAPAFLHVINDFNVKAIIVNSDVDH 1007
Query: 576 LLRSKEASNVLDSKAWPMTLDTDDMPKKKLPIMYRAPTAEMLAYLDFSV----STTGML- 630
++R K S + A + + + P E L Y+ ST M+
Sbjct: 1008 VMRQKLVSQHIKQSAQVLRIGVPAIYNTTKPTKQSHGCRE-LGYVVKDAWLQGSTPAMVW 1066
Query: 631 ---------AGIKMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYS 681
+ + H + +C+ K C++ +R + + LGF CL IY
Sbjct: 1067 TYWTPDQRRISVHIGHDTIMGMCKVQKETCQMSSARPVLGSVRSTLSLGFLHTCLMGIYV 1126
Query: 682 GHHSILIPPSEVEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLA 741
G + L+ P + NP +++YK++DT+ + ++ L ++ + KG L
Sbjct: 1127 GAPTYLVSPVDFATNPMTLFVTLARYKIKDTYAT-------SQMLDYAMTAMAGKGFQLQ 1179
Query: 742 CVRTCVVVAEERPRINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPSTV 801
++ ++ AE RPRI++ F++ L A++ + +N + + EP +
Sbjct: 1180 ELKNLMISAEGRPRIDIYQKVRLHFASASLDRTAINIVYSHVLNPMVVTRSYMCIEPIEL 1239
Query: 802 YVDLRALRNDRVSLVERGS-PHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQ 860
++DLRALR V + + P +L + +SG + ++ NPET GEIW+Q
Sbjct: 1240 WLDLRALRRGLVCPADPDTDPTALAVQDSGMVPVNTQIAIVNPETCTLSHVGEYGEIWIQ 1299
Query: 861 SPHNASGYFTIYGDESDYADH--FSAQLVTGNTGEVYARTGYLGFL 904
S A + YG + D+ DH F+ ++V G+ Y RTG LGFL
Sbjct: 1300 SDACAKAF---YGSKQDF-DHERFNGRIVDGDPSVAYVRTGDLGFL 1341
Score = 79.8 bits (188), Expect = 4e-13
Identities = 72/271 (26%), Positives = 127/271 (46%), Gaps = 29/271 (10%)
Query: 455 ISQILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVA 514
I +LR R++ S + +L+ KG +T +L +AE++ ++ +K + GD VA
Sbjct: 135 IPAVLRHRSRIHSKQAAYWVLDQKGKEIASITWEKLASRAEKVAQVIRDKSNLYRGDRVA 194
Query: 515 LIFPPG--LDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQS 572
LI+ ++ A GC G V V P N ++ +++ ++A L L+ ++
Sbjct: 195 LIYRDSEVIEFAVALMGCFIAGVVAV------PINSLEDYQSLNLVLTSTQAHLALTTEN 248
Query: 573 VIKLLRSKEASNVLDSKAWPMTLD---TDDM----PKKKLPIMYRAPTAEMLAYLDFSVS 625
+K + + L+ WP ++ T++ PKKK + LAY++FS +
Sbjct: 249 NLKSFQRDITAQKLN---WPRGVEWWKTNEFGSYHPKKKDDV--PPLVVPDLAYIEFSRA 303
Query: 626 TTGMLAGIKMSHAAV--TSLCRSMKIACELYPSR---H---IALCLDPYCGLGFALWCLS 677
TG L G+ MSH + C S I+ S+ H I LDP G+G L L
Sbjct: 304 PTGDLRGVVMSHRTIMHQMACLSAMISTVPGSSKVRSHGETIMSYLDPRHGIGMILGVLL 363
Query: 678 SIYSGHHSILIPPSEVEVNPALWLSAVSQYK 708
++Y GH ++ + VE P L+ +++Y+
Sbjct: 364 TVYGGHTTVWLEDRAVE-TPGLYAHLITKYR 393
Score = 56.8 bits (131), Expect = 3e-06
Identities = 27/54 (50%), Positives = 37/54 (68%), Gaps = 2/54 (3%)
Query: 952 VFVVGALDETIMLRGMRYHPIDIENSVMRCHKKIAE--CAVFTWTNLLVVVVEL 1003
+FV+G + ET + G+ + P+DIENSV RCH+ I CAVF L+VVVVE+
Sbjct: 1360 LFVLGGIGETFEVNGLNHFPMDIENSVERCHRNIVTGGCAVFQAGGLIVVVVEV 1413
Score = 40.3 bits (90), Expect = 0.27
Identities = 22/63 (34%), Positives = 30/63 (47%), Gaps = 2/63 (3%)
Query: 188 GQVMPSCVIVVVKMEGPAYLCKTDEVGEICVLSGATGSGYWGLPGLTNTVFRVRPLD-SD 246
G +P + VV E LC + +GEI V S + G+W LP T +F RP +
Sbjct: 589 GYPIPDATLAVVDPE-TNLLCTPNVIGEIWVDSPSLSGGFWALPKHTEAIFHARPYKFEE 647
Query: 247 GEP 249
G P
Sbjct: 648 GNP 650
Score = 39.1 bits (87), Expect = 0.63
Identities = 22/84 (26%), Positives = 41/84 (48%), Gaps = 9/84 (10%)
Query: 797 EPSTVYVDLRALRNDRVSLVERGS---------PHSLCLMESGKLLPGVKVITANPETKG 847
E V +D AL+++ + ++ G PH++ + G +P + +PET
Sbjct: 547 ELQEVLLDKEALKSNEIVVLAMGEEARKFAGSMPHAVRVGSFGYPIPDATLAVVDPETNL 606
Query: 848 QCGDSHLGEIWVQSPHNASGYFTI 871
C + +GEIWV SP + G++ +
Sbjct: 607 LCTPNVIGEIWVDSPSLSGGFWAL 630
>UniRef50_Q5YZV8 Cluster: Putative acyl-CoA synthetase; n=1;
Nocardia farcinica|Rep: Putative acyl-CoA synthetase -
Nocardia farcinica
Length = 699
Score = 167 bits (406), Expect = 1e-39
Identities = 127/457 (27%), Positives = 201/457 (43%), Gaps = 24/457 (5%)
Query: 456 SQILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVAL 515
+++LR RA SD + F L+ G ++ L +LH++AE + L ++ GD V L
Sbjct: 16 NELLRVRASEKSDDIAFVFLDDAGRQAQALDYGDLHRRAEALAARLTRDFKL--GDRVLL 73
Query: 516 IFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIK 575
+ PPGLD + +FY CLY G V V + PP ++ V + A V+S V+
Sbjct: 74 LHPPGLDYVVSFYACLYAGLVAVPLFPPQRNRVN----HVEAVARDCAAAAVVSTPEVLA 129
Query: 576 LLRSKEASNVLDSKAWPMTLDTDDMPKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKM 635
+ + + T TDD+P + P +AYL ++ +T G+ +
Sbjct: 130 EMANLSGDLFVSRLPRVSTEYTDDLPGEFEPPKI---GGSQIAYLQYTSGSTSAPKGVII 186
Query: 636 SHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIPPSEVEV 695
HA R + + E+ + + L + G L +Y G ++L+ PS
Sbjct: 187 DHAMALQQVRELAFSWEVDATSVVVSWLPHFHDFGQVSSVLMPVYVGGGAVLMAPSTFVK 246
Query: 696 NPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVVAEERPR 755
NP WL+AV++Y+ + +LC + + ++LA R V E R
Sbjct: 247 NPFRWLAAVTEYRGTHSGAPNFAFDLCV----DKITPAERAELDLASWR-LVSNGAEPVR 301
Query: 756 INLTNSFSKLFSALGLSPRAVSTSFG-CRVNIAICLQGASSPEPSTVYVDLRALRNDRV- 813
+ F K F+ GL+P A+S +G + +C G TV +D AL ++
Sbjct: 302 LGTLERFEKTFAPHGLAPTALSPGYGLAEATLKVC-SGTPDRRYRTVRLDDAALGRRKIV 360
Query: 814 -SLVERGSPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNASGYFTIY 872
S E GS L+ G + +V PET + GD LGEIWV P A GY +
Sbjct: 361 PSTAEHGSTE---LVGCGGTVLETEVAIVEPETGRRVGDDELGEIWVSGPIVAPGY---W 414
Query: 873 GDESDYADHFSAQLVTGNTGEVYARTGYLGFLRRTEI 909
D F A++ ++G Y RTG LGF+ E+
Sbjct: 415 NRPEDSEQTFRARIAGDDSGRTYLRTGDLGFVHEGEL 451
Score = 81.4 bits (192), Expect = 1e-13
Identities = 86/353 (24%), Positives = 146/353 (41%), Gaps = 19/353 (5%)
Query: 41 LNGMHVIFIPYALMKVSPASWMHMITKHRA--SIAIVKSRDLHWGLLATRDHKEISLSSL 98
+ G V+ P +K +P W+ +T++R S A + DL + + E+ L+S
Sbjct: 232 VGGGAVLMAPSTFVK-NPFRWLAAVTEYRGTHSGAPNFAFDLCVDKITPAERAELDLASW 290
Query: 99 RMLLVADGANPWSLSSCDQFLSVFQSKGVRGDAICP-CACSSESMTVCIXXXXXXXXXXX 157
R LV++GA P L + ++F F G+ A+ P + ++ VC
Sbjct: 291 R--LVSNGAEPVRLGTLERFEKTFAPHGLAPTALSPGYGLAEATLKVCSGTPDRRYRTVR 348
Query: 158 XXVLSMSGLSYGVVRVDAENSLTSLTLQDCGQVMPSCVIVVVKMEGPAYLCKTDEVGEIC 217
++ +V AE+ T L CG + + +V+ E + DE+GEI
Sbjct: 349 LDDAALGRRK--IVPSTAEHGSTELV--GCGGTVLETEVAIVEPETGRRV-GDDELGEIW 403
Query: 218 VLSGATGSGYWGLPGLTNTVFRVRPLDSDGEPIGEEHYVRSXXXXXXXXXXXXXXXXSRD 277
V GYW P + FR R D Y+R+ ++
Sbjct: 404 VSGPIVAPGYWNRPEDSEQTFRARIAGDDSG----RTYLRTGDLGFVHEGELFICGRVKN 459
Query: 278 GLMTVTGRKHNMDDIIATVLAVEPMKFIYRGRIAVFSVRVLRDERICIVAEQRPDCGEEE 337
LM V G + ++D+ ATV+ + + + G + FSV E + +VAE R D
Sbjct: 460 -LMIVNGVNYYLEDLEATVVGSD--EALRAGAVIAFSVERDGQENLVLVAEYRADTTRAP 516
Query: 338 SFQWMSRVLQAVDSIHQVGIYCLALVQPNFLPKTPLGGIHLSECKRRFLEGTL 390
+ ++ + AV H V + L+ +P+T G + +CK FL G+L
Sbjct: 517 E-ELVTVMHTAVSRKHAVAPAAIVLIAAGTIPRTTSGKLRRQQCKADFLAGSL 568
>UniRef50_Q1D6A2 Cluster: Non-ribosomal peptide synthase; n=1;
Myxococcus xanthus DK 1622|Rep: Non-ribosomal peptide
synthase - Myxococcus xanthus (strain DK 1622)
Length = 5741
Score = 164 bits (399), Expect = 1e-38
Identities = 127/456 (27%), Positives = 210/456 (46%), Gaps = 19/456 (4%)
Query: 457 QILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVALI 516
++L + QS + ++T L G VL+ A L +A RIG L R G+ L+
Sbjct: 34 ELLETQTQSLGERRLYTFLE-DGGDDAVLSYAGLDLRARRIGAALQALARA--GERAVLL 90
Query: 517 FPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKL 576
+PPGL+ + F+GCLY G V V PP P L TLP +R I+ ++A++VL+ + ++
Sbjct: 91 YPPGLEYVAGFFGCLYAGLVAVPAYPPDPMRLERTLPRLRAIIRDARASVVLTTSFIQEM 150
Query: 577 LRSK-EASNVLDSKAWPMTLDTDDMPKKKLPIMYR-APTAEMLAYLDFSVSTTGMLAGIK 634
E + L + W + TD +P+ R P+ + LA+L ++ +TG G++
Sbjct: 151 GEGLFEGAPELAALRW---VATDALPEGTEAGWRRPEPSRDTLAFLQYTSGSTGDPKGVQ 207
Query: 635 MSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIPPSEVE 694
+SH + + A ++ + L PY +G L +Y+G L+ P
Sbjct: 208 LSHGNLLHNLGLISHAFQVRSDSVGVIWLPPYHDMGLIGGILQPLYAGFPVALMSPLAFL 267
Query: 695 VNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVVAEE-R 753
P WL ++S++ + +LC + V + +G++L AE R
Sbjct: 268 RRPRFWLESLSRFGGTISGGPCFAFDLCVR----KVPPAEREGLDLRRWELAFCGAEPIR 323
Query: 754 PRINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPSTVYVDLRALRNDRV 813
P + FS+ F+ +G A+ +G I G T D +AL +
Sbjct: 324 PEV--MTRFSEAFAPVGFQREALYPCYGLAEGTLIASGGRKGEGVLTRMWDAQALERNEA 381
Query: 814 SLVERGSPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNASGYFTIYG 873
E G P + L+ G+ LP ++ +PET+ C +GEIWV P A GY+
Sbjct: 382 LAAEDG-PGARPLVGCGQTLPEQTLLVVDPETRRACPPERVGEIWVSGPSVAHGYWE-RP 439
Query: 874 DESDYADHFSAQLVTGNTGEVYARTGYLGFLRRTEI 909
+ES+ A F A+L ++G + RTG LG L+ E+
Sbjct: 440 EESEAA--FGARLADSDSGPRFLRTGDLGLLKDGEL 473
Score = 73.3 bits (172), Expect = 3e-11
Identities = 84/365 (23%), Positives = 140/365 (38%), Gaps = 20/365 (5%)
Query: 29 ETGLWHAVLASVLNGMHVIFI-PYALMKVSPASWMHMITKHRASIAIVKSRDLHWGLLAT 87
+ GL +L + G V + P A ++ P W+ +++ +I+ +
Sbjct: 241 DMGLIGGILQPLYAGFPVALMSPLAFLR-RPRFWLESLSRFGGTISGGPCFAFDLCVRKV 299
Query: 88 RDHKEISLSSLRMLLVADGANPWSLSSCDQFLSVFQSKGVRGDAICPCACSSESMTVCIX 147
+ L R L GA P +F F G + +A+ PC +E I
Sbjct: 300 PPAEREGLDLRRWELAFCGAEPIRPEVMTRFSEAFAPVGFQREALYPCYGLAEG--TLIA 357
Query: 148 XXXXXXXXXXXXVLSMSGLSYGVVRVDAENSLTSLTLQDCGQVMPSCVIVVVKMEGPAYL 207
+ L + AE+ + L CGQ +P ++VV E
Sbjct: 358 SGGRKGEGVLTRMWDAQALERNEA-LAAEDGPGARPLVGCGQTLPEQTLLVVDPE-TRRA 415
Query: 208 CKTDEVGEICVLSGATGSGYWGLPGLTNTVFRVRPLDSDGEPIGEEHYVRSXXXXXXXXX 267
C + VGEI V + GYW P + F R DSD P ++R+
Sbjct: 416 CPPERVGEIWVSGPSVAHGYWERPEESEAAFGARLADSDSGP----RFLRTGDLGLLKDG 471
Query: 268 XXXXXXXSRDGLMTVTGRKHNMDDIIATVLAVEPMKFIYRGRIAVFSVRVLRDERICIVA 327
+D L+ + GR + D+ T+ + G A FS+ V +ER+ ++
Sbjct: 472 ELFVVGRRKD-LIILRGRNLHPQDLELTL--ERSHSALRPGCGAAFSIDVGGEERLAVMY 528
Query: 328 E---QRPDCGEEESFQWMSRVLQAVDSIHQVGIYCLALVQPNFLPKTPLGGIHLSECKRR 384
E ++P E+ + V + + H+V ++ L L++P LPKT G I C+
Sbjct: 529 EVDSRKPWTAEDV----VGAVRRGLAETHEVQLHTLVLIEPGALPKTSSGKIQRRACRAE 584
Query: 385 FLEGT 389
L GT
Sbjct: 585 LLAGT 589
Score = 61.3 bits (142), Expect = 1e-07
Identities = 57/207 (27%), Positives = 92/207 (44%), Gaps = 19/207 (9%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPH 544
LT AEL ++A ++ L +G V G V L LDL+ G L G V + P +
Sbjct: 5151 LTYAELDRRANQLAWYLRNRG-VGPGTPVGLCVQRSLDLVVGMLGILKAGGAYVPLDPTY 5209
Query: 545 PQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKK 604
P+ + +V+ ++ +VL+ QSV+ LL S A VL AW D++ ++
Sbjct: 5210 PRE------RLAFMVEDTRLPVVLAQQSVVALLPSGSADVVLLDSAW------DEIAREP 5257
Query: 605 LPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIALCLD 664
AE LAY+ ++ +TG G+ + AV L + A + + + L L
Sbjct: 5258 TVSPRVTVPAESLAYVMYTSGSTGRPKGVCVPQRAVARLVLGSRFA--RWGADEVFLQLA 5315
Query: 665 PYC--GLGFALWCLSSIYSGHHSILIP 689
P C F +W ++ G +L P
Sbjct: 5316 PICFDAATFEVW--GALLHGAKLVLFP 5340
Score = 37.5 bits (83), Expect = 1.9
Identities = 38/159 (23%), Positives = 66/159 (41%), Gaps = 13/159 (8%)
Query: 482 SKVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIR 541
S LT EL ++A ++ L +G V VAL L+++ G L G V +
Sbjct: 2608 SDTLTYRELDRRANQLARYLRARG-VGPDTRVALCVERSLEMVVGLLGVLKAGGAYVPLD 2666
Query: 542 PPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMP 601
P +P+ M+ D + L+ + +L R LDS+ W D +
Sbjct: 2667 PEYPRER-----LEYMLADAAAPVLLTQARLSERLPRDSATVVCLDSE-W------DAVA 2714
Query: 602 KKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAV 640
+++ + LAY+ ++ +TG G +HAA+
Sbjct: 2715 REREERLDVTVDGSGLAYVLYTSGSTGRPKGAMNTHAAI 2753
>UniRef50_Q096N9 Cluster: Beta-ketoacyl synthase; n=1; Stigmatella
aurantiaca DW4/3-1|Rep: Beta-ketoacyl synthase -
Stigmatella aurantiaca DW4/3-1
Length = 745
Score = 159 bits (387), Expect = 3e-37
Identities = 125/454 (27%), Positives = 210/454 (46%), Gaps = 23/454 (5%)
Query: 459 LRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFP 518
LR AQ + ++T L+ G LT A+L +A I L + G TG V +++P
Sbjct: 37 LRHHAQHQPERRVYTFLSEAGEEESKLTFAQLDAQARAIAVELKKAGA--TGQRVVMLYP 94
Query: 519 PGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLR 578
L+ + A++GCLY V V PP P L TLP ++ IV + AT +L+ Q++ ++
Sbjct: 95 SCLEFVAAYFGCLYGNVVAVPAYPPEPARLQRTLPRLQAIVKNASATKILTTQAIKAMVG 154
Query: 579 -SKEASNVLDSKAWPMT--LDTDDMPKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKM 635
+ L W T +D + + + P + P + L++L ++ +T G+ +
Sbjct: 155 FFTPYAPELGEVEWIATDAVDVNQASEWQRPNI--GP--QTLSFLQYTSGSTATPKGVMV 210
Query: 636 SHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIPPSEVEV 695
+HA + + ++ + + + L + +G + + Y G H +L+ P+
Sbjct: 211 THANLVANTMALTSVVKTHRDSTLVCWLPLFHDMGLIGNVIHAAYVGFHCVLMAPTTFLQ 270
Query: 696 NPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVVAEERPR 755
NP LW+ A+S YK T ELC + V + ++L+ + T AE R
Sbjct: 271 NPFLWVKAMSDYKATFTGGPNFGYELCNR----KVTAEQRATLDLSHLETAYNGAEP-VR 325
Query: 756 INLTNSFSKLFSALGLSPRAVSTSFG-CRVNIAICLQGASSPEPSTVYVDLRALRNDRVS 814
F +LF GL A+ +G + + + + S P V D AL ++V
Sbjct: 326 YETLERFLELFGPQGLKRSAIKPCYGMAETTLVVSMMTSDSKGPILVMADGAALERNQVQ 385
Query: 815 LVERGSPHSLCLMESGKLL--PGVKVITANPETKGQCGDSHLGEIWVQSPHNASGYFTIY 872
VE + L+ SG + P +V+ PET +C + +GEIW+ P A GY+ +
Sbjct: 386 PVEGNPVGARSLVSSGNISTDPSQRVLIVRPETGVRCASNEVGEIWISGPSVARGYWNM- 444
Query: 873 GDESDYADHFSAQLVTGNTGE-VYARTGYLGFLR 905
DE++ F A L +TGE + RTG LG+LR
Sbjct: 445 SDETEAI--FHAYL--SDTGEGPFLRTGDLGYLR 474
Score = 87.4 bits (207), Expect = 2e-15
Identities = 82/374 (21%), Positives = 148/374 (39%), Gaps = 14/374 (3%)
Query: 20 MVCVLDFKRETGLWHAVLASVLNGMHVIFIPYALMKVSPASWMHMITKHRASIAIVKSRD 79
+VC L + GL V+ + G H + + +P W+ ++ ++A+ +
Sbjct: 234 LVCWLPLFHDMGLIGNVIHAAYVGFHCVLMAPTTFLQNPFLWVKAMSDYKATFTGGPNFG 293
Query: 80 LHWGLLATRDHKEISLSSLRMLLVADGANPWSLSSCDQFLSVFQSKGVRGDAICPCACSS 139
+ +L + +GA P + ++FL +F +G++ AI PC +
Sbjct: 294 YELCNRKVTAEQRATLDLSHLETAYNGAEPVRYETLERFLELFGPQGLKRSAIKPCYGMA 353
Query: 140 ESMTVCIXXXXXXXXXXXXXVLSMSGLSYGVVRVDAENSLTSLTLQDCGQVM--PSCVIV 197
E+ T+ + + + L V+ N + + +L G + PS ++
Sbjct: 354 ET-TLVVSMMTSDSKGPILVMADGAALERNQVQPVEGNPVGARSLVSSGNISTDPSQRVL 412
Query: 198 VVKMEGPAYLCKTDEVGEICVLSGATGSGYWGLPGLTNTVFRVRPLDSDGEPIGEEHYVR 257
+V+ E C ++EVGEI + + GYW + T +F D+ GE ++R
Sbjct: 413 IVRPE-TGVRCASNEVGEIWISGPSVARGYWNMSDETEAIFHAYLSDT-----GEGPFLR 466
Query: 258 SXXXXXXXXXXXXXXXXSRDGLMTVTGRKHNMDDIIATVLAVEPMKFIYRGRIAVFSVRV 317
+ L+ + G H DI T+ P + G A F V V
Sbjct: 467 TGDLGYLREDGELFITGRWKDLVIIRGTNHYPQDIERTMEQQHPA--MRPGCGAAFCVDV 524
Query: 318 LRDERICIVAEQRPDCGEEESFQ-WMSRVLQAVDSIHQVGIYCLALVQPNFLPKTPLGGI 376
+ER+ +V Q D + F + +V A++ H V Y L LV P + KT G I
Sbjct: 525 KNEERLVVV--QEVDANKVTDFDGLLEKVRNAINQSHGVQPYALVLVPPRSITKTSSGKI 582
Query: 377 HLSECKRRFLEGTL 390
C+ +L +
Sbjct: 583 QRRACRALWLSNEM 596
>UniRef50_A3ILP8 Cluster: Beta-ketoacyl synthase; n=1; Cyanothece
sp. CCY 0110|Rep: Beta-ketoacyl synthase - Cyanothece
sp. CCY 0110
Length = 689
Score = 158 bits (384), Expect = 7e-37
Identities = 110/455 (24%), Positives = 194/455 (42%), Gaps = 20/455 (4%)
Query: 452 YQFISQILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGD 511
++ + Q+L +Q +H +T+L+ G +T ELH +A++I LL G +
Sbjct: 6 FKTLGQVLTHWSQIQPEHKAYTMLDNNGVEESHITYGELHSQAKKIAQTLLGSGLQSR-- 63
Query: 512 HVALIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQ 571
+V L++PPG+D I AF+GCLY G +P I P + + ++ +D + + + +
Sbjct: 64 NVILLYPPGIDFIIAFFGCLYAGVIPAPIHAPKRNRSNQKIASLVHSIDAAAILVPEAQK 123
Query: 572 SVIKLLRSKEAS--NVLDSKAWPMTLDTDDMPKKKLPIMYRAPTAEMLAYLDFSVSTTGM 629
+ SKE + L + + +LP + LA+L F+ +T +
Sbjct: 124 ETYDQILSKEENWPEELPYIVTDRLFNLSPLATPELPDL----DGSTLAFLQFTSGSTSL 179
Query: 630 LAGIKMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIP 689
G+ +SH+ S P L Y LG L S Y G H +++
Sbjct: 180 PKGVMISHSNCLSNLEMALSVTSATPESTFVSWLPHYHDLGLVAHLLHSFYGGSHCVILA 239
Query: 690 PSEVEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVV 749
P+ P WL A++ Y + T +LC + + K ++L+C+R +
Sbjct: 240 PTTFVSRPLEWLRAITNYGGQYTGAPNFAYQLCV----DKIRPEEQKNLDLSCLRMAINA 295
Query: 750 AEERPRINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPSTVYVDLRALR 809
AE L + FS+ F+ G P+ ++G G EP + +DL L
Sbjct: 296 AEPINAQTLLD-FSEKFAENGFKPQMFLPAYGMAEGTVFISSGTLEQEPVYLEIDLDILG 354
Query: 810 NDRVSLVERGSPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNASGYF 869
D +++ H L+ G G ++ +P+ + H+GE+WV P+ +GY+
Sbjct: 355 KDNIAVETNNDTHKKRLVGCGHGKLGEQLFIIDPQRNCEVPRYHVGEVWVTGPNIMAGYY 414
Query: 870 TIYGDESDYADHFSAQLVTGNTGEVYARTGYLGFL 904
+ + LV+ +Y RTG LGF+
Sbjct: 415 -------QNPEATAKTLVSQKGDRLYLRTGDLGFM 442
Score = 46.0 bits (104), Expect = 0.006
Identities = 82/398 (20%), Positives = 140/398 (35%), Gaps = 26/398 (6%)
Query: 2 LAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLASVLNGMHVIFIPYALMKVSPASW 61
L++ M + T V L + GL +L S G H + + P W
Sbjct: 191 LSNLEMALSVTSATPESTFVSWLPHYHDLGLVAHLLHSFYGGSHCVILAPTTFVSRPLEW 250
Query: 62 MHMITKHRASIAIVKS--RDLHWGLLATRDHKEISLSSLRMLLVADGANPWSLSSCDQFL 119
+ IT + + L + + K + LS LRM + A A P + + F
Sbjct: 251 LRAITNYGGQYTGAPNFAYQLCVDKIRPEEQKNLDLSCLRMAINA--AEPINAQTLLDFS 308
Query: 120 SVFQSKGVRGDAICPCACSSESMTVCIXXXXXXXXXXXXXVLSMSGLSYGVVRVDAENSL 179
F G + P +E TV I + + L + V+ N
Sbjct: 309 EKFAENGFKPQMFLPAYGMAEG-TVFISSGTLEQEPVYLEI-DLDILGKDNIAVETNNDT 366
Query: 180 TSLTLQDCGQVMPSCVIVVVKMEGPAYLCKTDE--VGEICVLSGATGSGYWGLPGLTNTV 237
L CG + ++ P C+ VGE+ V +GY+ P T
Sbjct: 367 HKKRLVGCGHGKLGEQLFIID---PQRNCEVPRYHVGEVWVTGPNIMAGYYQNPEAT--- 420
Query: 238 FRVRPLDSDGEPIGEEHYVRSXXXXXXXXXXXXXXXXSRDGLMTVTGRKHNMDDIIATVL 297
+ L S G+ Y+R+ L+ V G + DI +
Sbjct: 421 --AKTLVSQK---GDRLYLRTGDLGFMDEDGELYITGRLKDLIIVNGVNYYPQDI--EIC 473
Query: 298 AVEPMKFIYRGRIAVFSVRVLRDERICIVAE-QRPDCGEEESFQWMSRVLQAVDSI---- 352
+ K I G + FSV E + IVAE + + ++ +++A+ S
Sbjct: 474 VGQAHKDIRSGCVIAFSVPGKTAEELVIVAELNKAGMTKMGQSGYLEEMVEAISSKIGEE 533
Query: 353 HQVGIYCLALVQPNFLPKTPLGGIHLSECKRRFLEGTL 390
++ + L ++ +PKT G + +CK+ FL+ +L
Sbjct: 534 FELSVTQLVFLRIGRIPKTSSGKLQRQQCKQMFLQESL 571
>UniRef50_Q1D5W2 Cluster: Non-ribosomal peptide
synthetase/polyketide synthase; n=27; root|Rep:
Non-ribosomal peptide synthetase/polyketide synthase -
Myxococcus xanthus (strain DK 1622)
Length = 14274
Score = 158 bits (383), Expect = 9e-37
Identities = 127/451 (28%), Positives = 195/451 (43%), Gaps = 16/451 (3%)
Query: 457 QILRWRAQSTSDH-VIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVAL 515
++L RA S + H + L L+ ELH +A RIG LL +G G V L
Sbjct: 10 EVLTQRAFSETAHRKQYAFLGDSEGEEASLSARELHAQAARIGALLQAQGA--QGQRVLL 67
Query: 516 IFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIK 575
++PPGLD + F+GCLY GAV V PP P L TLP +R I+ ++AT+VL+ ++
Sbjct: 68 LYPPGLDYVAGFFGCLYAGAVAVPAYPPDPVRLERTLPRLRAIIQDAEATVVLTTSGILS 127
Query: 576 LLRSK-EASNVLDSKAWPMTLDTDDMPK-KKLPIMYRAPTAEMLAYLDFSVSTTGMLAGI 633
L E + + W L TD++P + + + + LA+L ++ +TG G+
Sbjct: 128 LADFVFEQAPDFRALKW---LATDELPAGGESSWIEPQVSPDTLAFLQYTSGSTGTPKGV 184
Query: 634 KMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIPPSEV 693
+SHA + + A + P + L PY +G L +++G L+ P
Sbjct: 185 MLSHANLIHNLGLIAGAFQTGPQSSGVIWLPPYHDMGLIGGILQPLFAGFPVTLMSPMSF 244
Query: 694 EVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVVAEER 753
P WL AVS+Y + ELC + ++ +++ + V C E
Sbjct: 245 LQRPMRWLEAVSRYGGTISGGPNFAFELCAR--RATPEDIQALDLRAWDVAFC---GAEP 299
Query: 754 PRINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPSTVYVDLRALRNDRV 813
R + F+++F+ G A +G I P + AL +
Sbjct: 300 IRAATLDRFAEVFAPSGFRREAFYPCYGLAEGTLIVTGEEKGRVPRVHVLQDAALGRGQA 359
Query: 814 SLVERGSPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNASGYFTIYG 873
VE GS S + G L +++ +PE++ C +GEIWV A GY +
Sbjct: 360 VRVEPGSEGSRPHIGCGSTLAEQRLLIVDPESRVPCAPGQVGEIWVSGGSVAQGY---WR 416
Query: 874 DESDYADHFSAQLVTGNTGEVYARTGYLGFL 904
D D F A V G Y RTG LG L
Sbjct: 417 KPEDSVDIFQAVPVGAEAGPKYLRTGDLGLL 447
Score = 77.0 bits (181), Expect = 3e-12
Identities = 91/369 (24%), Positives = 144/369 (39%), Gaps = 19/369 (5%)
Query: 29 ETGLWHAVLASVLNGMHVIFIPYALMKVSPASWMHMITKHRASIAIVKSRDLHWGLLATR 88
+ GL +L + G V + P W+ ++++ +I+ + + L A R
Sbjct: 219 DMGLIGGILQPLFAGFPVTLMSPMSFLQRPMRWLEAVSRYGGTIS--GGPNFAFELCARR 276
Query: 89 DHKE-ISLSSLRMLLVAD-GANPWSLSSCDQFLSVFQSKGVRGDAICPCACSSESMTVCI 146
E I LR VA GA P ++ D+F VF G R +A PC +E I
Sbjct: 277 ATPEDIQALDLRAWDVAFCGAEPIRAATLDRFAEVFAPSGFRREAFYPCYGLAEG--TLI 334
Query: 147 XXXXXXXXXXXXXVLSMSGLSYG-VVRVDAENSLTSLTLQDCGQVMPSCVIVVVKMEGPA 205
VL + L G VRV+ S S CG + +++V E
Sbjct: 335 VTGEEKGRVPRVHVLQDAALGRGQAVRVEP-GSEGSRPHIGCGSTLAEQRLLIVDPESRV 393
Query: 206 YLCKTDEVGEICVLSGATGSGYWGLPGLTNTVFRVRPLDSDGEPIGEEHYVRSXXXXXXX 265
C +VGEI V G+ GYW P + +F+ P+ ++ P Y+R+
Sbjct: 394 P-CAPGQVGEIWVSGGSVAQGYWRKPEDSVDIFQAVPVGAEAGP----KYLRTGDLGLLL 448
Query: 266 XXXXXXXXXSRDGLMTVTGRKHNMDDIIATVLAVEPMKFIYRGRIAVFSVRVLRDERICI 325
R L+ + GR D+ + V + + G IA F++ E + +
Sbjct: 449 EDGQLIVTGRRKDLIILRGRNLYPQDVESIVERAH--RKVRPGCIAAFAIETPEGEALAV 506
Query: 326 VAEQRPDCGEEESFQWMSRVL----QAVDSIHQVGIYCLALVQPNFLPKTPLGGIHLSEC 381
VAE D E + V +A+ + QV + LAL+ P + KT G I C
Sbjct: 507 VAEVSRDVAEGADPAALGAVADTLRKAIVAELQVQPHTLALLPPGSVMKTSSGKIQRFAC 566
Query: 382 KRRFLEGTL 390
+ + G L
Sbjct: 567 RAALVSGEL 575
Score = 37.5 bits (83), Expect = 1.9
Identities = 55/236 (23%), Positives = 98/236 (41%), Gaps = 20/236 (8%)
Query: 483 KVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRP 542
+VL+ ++L+ KA ++ L G V V L L+ I + L G V I P
Sbjct: 12382 QVLSFSQLNAKANQLAAHLRTLG-VGPEVRVGLCLERTLEAIISLLAVLKAGGAFVPIDP 12440
Query: 543 PHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPK 602
P + +++ S AT++L+ Q + + R + +VL LDT+
Sbjct: 12441 MAPSQRRS------FMLEDSGATVLLTVQHLAEAWRP-QVRHVL-------CLDTEAARL 12486
Query: 603 KKLPIMYRAPT---AEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHI 659
LP Y P E LAY+ ++ +TG G+ + H ++ L + M + E+
Sbjct: 12487 ASLPT-YNVPANVRGENLAYIIYTSGSTGTPKGVMVQHRSLPWLLQGMTESLEMAEPAGQ 12545
Query: 660 ALCLDPYCGLGFALWCLSSIYSGHHSILIPPSEVEVNPALWLSAVSQYKVRDTFCS 715
L L+ + L + GH L+P + +P ++ + Q +V C+
Sbjct: 12546 RLSLNAPLYFDGTVERLMHLAEGHCLCLVPEA-TRKDPEAMVAWLEQQRVDMLDCT 12600
Score = 36.3 bits (80), Expect = 4.5
Identities = 44/168 (26%), Positives = 76/168 (45%), Gaps = 15/168 (8%)
Query: 482 SKVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIR 541
S+ LT EL KA ++ + L G V V + +D++ A G L GA V +
Sbjct: 9185 SERLTYRELDAKANQVAHHLRGLG-VAPESLVGVCLERSVDMVVALLGVLKAGAAYVPVD 9243
Query: 542 PPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNV-LDSKAWPMTLDTDDM 600
P +P+ + +++ + A+++L+++ +L A V LDS A +
Sbjct: 9244 PAYPKE------RLGWMLEDTGASVLLTHEKWKTVLPPSAARVVCLDSAAGEVA----KQ 9293
Query: 601 PKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMK 648
P K P + P A LAY+ F+ +TG G +H V + + M+
Sbjct: 9294 PVTK-PAVQVGPQA--LAYVIFTSGSTGRPKGAMNAHGGVVNRLKWMQ 9338
Score = 35.9 bits (79), Expect = 5.9
Identities = 44/168 (26%), Positives = 76/168 (45%), Gaps = 15/168 (8%)
Query: 482 SKVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIR 541
S+ LT EL KA ++ + L G V V + +D++ A G L GA V +
Sbjct: 1179 SERLTYRELDAKANKLAHHLRGLG-VAPESLVGVCLERSVDMVVALLGVLKAGAAYVPVD 1237
Query: 542 PPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNV-LDSKAWPMTLDTDDM 600
P +P+ + +++ + A+++L+++ +L A V LDS A +
Sbjct: 1238 PAYPKE------RLGWMLEDTGASVLLTHEKWKTVLPPSAARVVCLDSAAGEVA----KQ 1287
Query: 601 PKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMK 648
P K P + P A LAY+ F+ +TG G +H V + + M+
Sbjct: 1288 PVTK-PAVQVGPQA--LAYVIFTSGSTGRPKGAMNAHEGVVNRLKWMQ 1332
>UniRef50_Q08XI8 Cluster: Beta-lactamase, putative; n=3;
Bacteria|Rep: Beta-lactamase, putative - Stigmatella
aurantiaca DW4/3-1
Length = 3136
Score = 157 bits (382), Expect = 1e-36
Identities = 124/461 (26%), Positives = 210/461 (45%), Gaps = 28/461 (6%)
Query: 457 QILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVALI 516
++L +A T D +FT K L+ EL +A I + + G+ L+
Sbjct: 50 ELLEEKASLTPDQPLFTFQEETEGEEKTLSYGELRYRALTIARSV--QALAAPGERALLL 107
Query: 517 FPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKL 576
+PPGL+ I F+GCLY G V V PP P L+ TLP +R ++ ++A +VL+ ++ +
Sbjct: 108 YPPGLEYIAGFFGCLYAGMVAVPAYPPDPLRLNRTLPRLRAMIQDAQAKVVLTTSFILSM 167
Query: 577 LRSK-EASNVLDSKAWPMTLDTDDMPKKKLPIMYRAP--TAEMLAYLDFSVSTTGMLAGI 633
S E + W + TDD+P K P + P + LA+L ++ +TG G+
Sbjct: 168 GESLFEQEPDFKNLHW---IATDDLP-KGAPDRWVQPSVSGNTLAFLQYTSGSTGAPKGV 223
Query: 634 KMSHAAVTSLCRSMKIACELYPSRHIALC---LDPYCGLGFALWCLSSIYSGHHSILIPP 690
++H + LC ++++ + R ++C L PY +G L +Y+G + L+ P
Sbjct: 224 MLTHDNL--LC-NLEMIAHTFQIRSDSVCVIWLPPYHDMGLIGGILEPVYTGMRTTLMSP 280
Query: 691 SEVEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVVA 750
NP WL +S+ K + +LC + V + + ++L+ + A
Sbjct: 281 MSFLKNPFRWLDTISRLKATVSGGPNFAFDLCVR----KVTAEQRQRLDLSHWKVAFSGA 336
Query: 751 EERPRINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPSTVYVDLRALRN 810
E R + F++ F G +A +G + + G PEP + LRA
Sbjct: 337 EP-IRPETLDRFTQTFETCGFRRKAFFPCYGL-AEATLIVSGGEVPEP-PILCSLRASAL 393
Query: 811 DRVSLVE--RGSPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNASGY 868
++ VE G S L+ G+ +P +++ +P + C +GEIWV P A GY
Sbjct: 394 EQGQAVEAPSGELDSRTLVGCGQTVPNQEILIVDPVSSVPCPPGKVGEIWVCGPSVAQGY 453
Query: 869 FTIYGDESDYADHFSAQLVTGNTGEVYARTGYLGFLRRTEI 909
+ ++ F A+ +G VY RTG LGFL+ E+
Sbjct: 454 ---WQKPTETGQIFQARPASGGE-RVYLRTGDLGFLKEREL 490
Score = 100 bits (240), Expect = 2e-19
Identities = 100/397 (25%), Positives = 161/397 (40%), Gaps = 25/397 (6%)
Query: 5 CRMLSVACNYTEGEHMVCVLDFK--RETGLWHAVLASVLNGMHVIFI-PYALMKVSPASW 61
C + +A + VCV+ + GL +L V GM + P + +K +P W
Sbjct: 232 CNLEMIAHTFQIRSDSVCVIWLPPYHDMGLIGGILEPVYTGMRTTLMSPMSFLK-NPFRW 290
Query: 62 MHMITKHRASIAIVKSR--DLHWGLLATRDHKEISLSSLRMLLVADGANPWSLSSCDQFL 119
+ I++ +A+++ + DL + + + LS ++ GA P + D+F
Sbjct: 291 LDTISRLKATVSGGPNFAFDLCVRKVTAEQRQRLDLSHWKVAF--SGAEPIRPETLDRFT 348
Query: 120 SVFQSKGVRGDAICPCACSSESMTVCIXXXXXXXXXXXXXVLSMSGLSYGVVRVDAENSL 179
F++ G R A PC +E+ I L S L G L
Sbjct: 349 QTFETCGFRRKAFFPCYGLAEA--TLIVSGGEVPEPPILCSLRASALEQGQAVEAPSGEL 406
Query: 180 TSLTLQDCGQVMPSCVIVVVKMEGPAYLCKTDEVGEICVLSGATGSGYWGLPGLTNTVFR 239
S TL CGQ +P+ I++V + C +VGEI V + GYW P T +F+
Sbjct: 407 DSRTLVGCGQTVPNQEILIVDPVS-SVPCPPGKVGEIWVCGPSVAQGYWQKPTETGQIFQ 465
Query: 240 VRPLDSDGEPIGEEHYVRSXXXXXXXXXXXXXXXXSRDGLMTVTGRKHNMDDIIATVLAV 299
RP GE Y+R+ +D L+ + GR H D+ T
Sbjct: 466 ARPASG-----GERVYLRTGDLGFLKERELFVTGRQKD-LIIIRGRNHFPQDLELTAEQS 519
Query: 300 EPMKFIYRGRIAVFSVRVLRDERICIVAEQRPDCGEEESFQW------MSRVLQAVDSIH 353
P + G A FSV +E++ +V E + Q + + Q + +H
Sbjct: 520 HPS--LRPGCSAAFSVDWEGEEKLVLVQEVDVRKAGDLRAQLDVCKAAATALRQRLAEVH 577
Query: 354 QVGIYCLALVQPNFLPKTPLGGIHLSECKRRFLEGTL 390
+V ++ LAL++P + KT G I S C+ FL G L
Sbjct: 578 EVQLHALALIEPGTIFKTSSGKIQRSACREAFLSGAL 614
>UniRef50_Q2SHY7 Cluster: Polyketide synthase modules and related
protein; n=13; cellular organisms|Rep: Polyketide
synthase modules and related protein - Hahella
chejuensis (strain KCTC 2396)
Length = 3637
Score = 157 bits (380), Expect = 2e-36
Identities = 129/475 (27%), Positives = 211/475 (44%), Gaps = 25/475 (5%)
Query: 446 SDAARKYQF--ISQILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLE 503
+DA R+ F I L+ A + D F L LT AEL ++A R+ LL
Sbjct: 25 TDATRRPFFADIRCALQSHAITRGDADAFVFLTEDREARFPLTYAELDRQARRVAALL-- 82
Query: 504 KGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSK 563
+G GD L+F PGL+ + AF+GC+Y G VT P HP + + + I+D +
Sbjct: 83 RGHAQPGDRALLLFHPGLEFLAAFFGCMYAG---VTAIPMHPPKKNRSAERLDSILDDAD 139
Query: 564 ATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDT---DDMPKKKLPIMYRAPT---AEML 617
A ++L+N SV+ + +A + +A +T+D + + AP + L
Sbjct: 140 ARVILANDSVVAAIADADAGDKRLREAVWLTVDAILLNGTDSARASDKDSAPAFLHGDDL 199
Query: 618 AYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLS 677
A+L ++ +T G+ +SH + + + L + LG L+
Sbjct: 200 AFLQYTSGSTSAPKGVMVSHRNLILNLDELHRCFGHDDDSILVSWLPHFHDLGLIYAILT 259
Query: 678 SIYSGHHSILIPPSEVEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKG 737
+Y+G L+ P+ NP WL A+S + + +LC + + + +
Sbjct: 260 PLYAGSICYLMAPATFIRNPMRWLQAISDCRATHSAAPNFAYQLCIDKISAD----QKRT 315
Query: 738 INLACVRTCVVVAEERPRINLTNSFSKLFSALGLSPRAVSTSFG-CRVNIAICLQGASSP 796
++L+C R AE R F+ FS G S A+S S+G + + + S P
Sbjct: 316 LDLSCWRAACNAAEP-VRYETLRGFAAAFSDCGFSYDALSPSYGLAEATVKVSITPISEP 374
Query: 797 EPSTVYVDLRALRNDRVSLVERGSPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGE 856
P+ ++V+ AL +V +V +P S L+ SG++ K + + ET+ C +GE
Sbjct: 375 -PTVLHVEREALSQGKVRVVAADAPGSTPLVGSGRVDMDTKSLIVDAETQTPCLPDEIGE 433
Query: 857 IWVQSPHNASGYFTIYGDESDYADHFSAQLVT--GNTGEVYARTGYLGFLRRTEI 909
IWV+ P ASGY + AD F A L G Y RTG LGF+ ++
Sbjct: 434 IWVRGPSVASGY---WARPEATADTFDAHLANPQGRYPGPYLRTGDLGFIHGAQL 485
Score = 87.4 bits (207), Expect = 2e-15
Identities = 98/376 (26%), Positives = 151/376 (40%), Gaps = 13/376 (3%)
Query: 20 MVCVLDFKRETGLWHAVLASVLNGMHVIFIPYALMKVSPASWMHMITKHRA--SIAIVKS 77
+V L + GL +A+L + G + A +P W+ I+ RA S A +
Sbjct: 241 LVSWLPHFHDLGLIYAILTPLYAGSICYLMAPATFIRNPMRWLQAISDCRATHSAAPNFA 300
Query: 78 RDLHWGLLATRDHKEISLSSLRMLLVADGANPWSLSSCDQFLSVFQSKGVRGDAICPCAC 137
L ++ + + LS R + A P + F + F G DA+ P
Sbjct: 301 YQLCIDKISADQKRTLDLSCWRA--ACNAAEPVRYETLRGFAAAFSDCGFSYDALSPSYG 358
Query: 138 SSESMTVCIXXXXXXXXXXXXXVLSMSGLSYGVVRVDAENSLTSLTLQDCGQVMPSCVIV 197
+E+ TV + V LS G VRV A ++ S L G+V +
Sbjct: 359 LAEA-TVKVSITPISEPPTVLHV-EREALSQGKVRVVAADAPGSTPLVGSGRVDMDTKSL 416
Query: 198 VVKMEGPAYLCKTDEVGEICVLSGATGSGYWGLPGLTNTVFRVRPLDSDGEPIGEEHYVR 257
+V E C DE+GEI V + SGYW P T F + G G Y+R
Sbjct: 417 IVDAETQTP-CLPDEIGEIWVRGPSVASGYWARPEATADTFDAHLANPQGRYPGP--YLR 473
Query: 258 SXXXXXXXXXXXXXXXXSRDGLMTVTGRKHNMDDIIATVLAVEPMKFIYRGRIAVFSVRV 317
+ +D L+ + G + DI TV A P G A FSV +
Sbjct: 474 TGDLGFIHGAQLFITGRRKD-LLIIDGVNYYPQDIEKTVFACHPDLTADNG--AAFSVDI 530
Query: 318 LRDERICIVAE-QRPDCGEEESFQWMSRVLQAVDSIHQVGIYCLALVQPNFLPKTPLGGI 376
+ER+ IV E +R + + + + QAV H++ +Y +AL++P KT G I
Sbjct: 531 DGEERLVIVQEVKRTAVRQLDGDAVVRAIRQAVFQEHELPVYAIALLKPLQAYKTTSGKI 590
Query: 377 HLSECKRRFLEGTLHP 392
++ +LEG + P
Sbjct: 591 QRQANRKAWLEGAMQP 606
Score = 37.9 bits (84), Expect = 1.5
Identities = 51/241 (21%), Positives = 104/241 (43%), Gaps = 18/241 (7%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPH 544
L+ AEL+++A + L E+G G V L ++LI G L G + + P H
Sbjct: 3046 LSYAELNRRANGVAACLREQG-TPAGAAVGLCVSRNVNLIVGLLGILKSGCGYLPLDPTH 3104
Query: 545 PQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKK 604
P + + D A LV ++++++ L + E L + W D ++
Sbjct: 3105 PPARLSA-----QLQDACVAALV-TDRAIMPTLAALEG---LGAAQWVCVEDVTATAEE- 3154
Query: 605 LPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSM--KIACELYPSRHIALC 662
P + P + LAYL ++ +TG G + H +V +L ++ ++ +ALC
Sbjct: 3155 -PEVAIGP--DSLAYLIYTSGSTGAPKGTLVEHRSVLNLANALWDQVYHRYDQPIAVALC 3211
Query: 663 LDPYCGLGFALWCLSSIYSGHHSILIPPSEVEVNPALWLSAVSQYKVRDTFCSYGVMELC 722
+ +++ GH +++ ++ +PA + ++ +VR C+ ++ +
Sbjct: 3212 ANTVFDAS-VQQIFAALLLGHQLVIV-DADSRRDPARLSALLAAEQVRVADCTPSLLSML 3269
Query: 723 T 723
T
Sbjct: 3270 T 3270
>UniRef50_Q7RZX2 Cluster: Putative uncharacterized protein NCU00239.1;
n=2; Pezizomycotina|Rep: Putative uncharacterized protein
NCU00239.1 - Neurospora crassa
Length = 1945
Score = 157 bits (380), Expect = 2e-36
Identities = 134/573 (23%), Positives = 240/573 (41%), Gaps = 40/573 (6%)
Query: 344 RVLQAVDSIHQVGIYCLALVQPNFLPKTPLGG---IHLSECKRRFLEGTLHPSNVLMCPH 400
R + + H + +YC+ + PN LP+ G I C+R F +G L +V
Sbjct: 952 RCMDVLMQEHHLRVYCVMITAPNALPRVMKNGRKEIGNMLCRREFDQGNLPCVHVKFAVE 1011
Query: 401 TCVTNLPKPREIHSDVGPASVIVGN---LVQGNRLASAQGRDMGYTDD--SDAARKYQFI 455
V NLP + + L ++ S R DD S + I
Sbjct: 1012 HAVLNLPIGVDPIGGIWSPMASESRQQILAPADKQYSGIDRREVVIDDRTSTPLNNFSSI 1071
Query: 456 SQILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVAL 515
+ +++WR + + + ++ +G K +T + K + L K ++ GDHV L
Sbjct: 1072 TDLIQWRVARQPEELAYCTIDGRGKEGKGITWKKFDTKVAAVALYLRNKIKIRAGDHVVL 1131
Query: 516 IFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIK 575
++ + + A + C+ +GA+ + + P L +P +V VL NQ V
Sbjct: 1132 MYTHSEEFVFAVHACINLGAIIIPVAPMDQNRLSEDVPAFLHLVADYGVKAVLVNQDVDH 1191
Query: 576 LLRSKEASNVLDSKAWPMTLDTDDMPKKKLPIMYRA--PTAEMLAYLDFSVSTTGMLAGI 633
LL++K + + A K ++P +Y P + D ++ + +
Sbjct: 1192 LLKTKPVAQHIKQSA--------QFLKVQVPNVYNTSKPPKQNSGLRDLGITVDP--SWV 1241
Query: 634 KMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIPPSEV 693
K + V + R +A+ L LGF CL IY G + L+ P E
Sbjct: 1242 KSGYPVVIWTYWTPD-------QRRLAVQLSHDTILGFIHTCLMGIYIGTPTYLLSPVEF 1294
Query: 694 EVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVVAEER 753
NP +S+YK++DT+ + +++ +++ + KG L ++ ++ E R
Sbjct: 1295 AQNPVSLFLILSRYKIKDTYATPQMLD-------HAMSMIPGKGFTLHELKNMMISCESR 1347
Query: 754 PRINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPSTVYVDLRALRNDRV 813
PR++L F A GL A++T + +N I + EP +++D +ALR +
Sbjct: 1348 PRVDLFTRVRVHFDATGLDRTAINTVYSHVLNPMIASRSYMCVEPIELHLDPKALRQGLI 1407
Query: 814 SLVE-RGSPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNASGYFTIY 872
+ P +L + +SG + ++ NPE++ C D GEIWV S + + Y
Sbjct: 1408 YPTDPLRDPKALVIQDSGMVPVSTQIAIVNPESRMLCSDGEYGEIWVDSEACVTSF---Y 1464
Query: 873 GDESDY-ADHFSAQLVTGNTGEVYARTGYLGFL 904
G + + + F+ + V + Y RTG LGFL
Sbjct: 1465 GSKDQFDVERFNGRTVE-DPSIRYVRTGDLGFL 1496
Score = 60.9 bits (141), Expect = 2e-07
Identities = 49/191 (25%), Positives = 88/191 (46%), Gaps = 12/191 (6%)
Query: 455 ISQILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVA 514
I+ +LR R ++ + + +L+AKG +T +L +AE++ ++ +K + GD VA
Sbjct: 302 IAVVLRHRGRNLPNRRAYWVLDAKGKEIASITWDKLASRAEKVAQVIRDKSSLYRGDRVA 361
Query: 515 LIFPPG--LDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQS 572
LI+ +D A GC G V V P N + +I+ ++A L L+ +
Sbjct: 362 LIYRDAEIIDFAIALLGCFIAGVVAV------PINELQDYQKLNVILTSTQAHLALTTDN 415
Query: 573 VIKLLRSKEASNVL---DSKAWPMTLDTDDMPKKKLPIMYRAPTAEMLAYLDFSVSTTGM 629
+K + + L W T + +KK + + LAY++FS + TG
Sbjct: 416 NLKAFQRDITTQKLHWPKGVEWWKTNEFGSYSQKKKDELPPLSVPD-LAYIEFSRAPTGD 474
Query: 630 LAGIKMSHAAV 640
L G+ +SH +
Sbjct: 475 LRGVVLSHRTI 485
Score = 51.6 bits (118), Expect = 1e-04
Identities = 25/54 (46%), Positives = 37/54 (68%), Gaps = 2/54 (3%)
Query: 952 VFVVGALDETIMLRGMRYHPIDIENSVMRCHKKIAE--CAVFTWTNLLVVVVEL 1003
+FV+G++ ET + G+ + P+DIE SV RCH+ I CAVF L+VV+VE+
Sbjct: 1515 LFVLGSIGETFEINGLSHFPMDIEASVERCHRVIVPGGCAVFQAGGLVVVLVEV 1568
Score = 36.7 bits (81), Expect = 3.4
Identities = 21/68 (30%), Positives = 31/68 (45%), Gaps = 1/68 (1%)
Query: 175 AENSLTSLTLQDCGQVMPSCVIVVVKMEGPAYLCKTDEVGEICVLSGATGSGYWGLPGLT 234
A + L ++ + G +P + +V E L VGEI V S + G+W LP T
Sbjct: 760 ASSELGTVRVGAFGYPIPDASLAIVDPE-TGLLASPHTVGEIWVDSPSLSGGFWALPKHT 818
Query: 235 NTVFRVRP 242
+F RP
Sbjct: 819 EQIFHARP 826
>UniRef50_Q1D438 Cluster: Non-ribosomal peptide synthase; n=8;
Bacteria|Rep: Non-ribosomal peptide synthase -
Myxococcus xanthus (strain DK 1622)
Length = 3906
Score = 154 bits (373), Expect = 1e-35
Identities = 114/451 (25%), Positives = 200/451 (44%), Gaps = 20/451 (4%)
Query: 459 LRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFP 518
LR RA + D + +T + + ++ EL ++A I L G+ L++P
Sbjct: 20 LRHRASTQPDAIAYTFVGDDASDETRISYRELDRRARAIAASLQRMDAA--GERAILLYP 77
Query: 519 PGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLR 578
PGLD + AF GCLY + V PP L+ +LP ++ I+ ++A++VL+ + ++ L+
Sbjct: 78 PGLDYVAAFLGCLYANVIAVPAYPPDISRLNRSLPRLQAILTDARASIVLTTEMILSLVD 137
Query: 579 S-KEASNVLDSKAWPMTLDTDDMPKKKLPIMYRAP--TAEMLAYLDFSVSTTGMLAGIKM 635
S +E ++ L + W T D+ + +R P T + LA+L ++ +TG G+ +
Sbjct: 138 SLEEQASQLRDRRWLAT----DLLEAGCEDGWREPEVTGQTLAFLQYTSGSTGTPKGVML 193
Query: 636 SHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIPPSEVEV 695
+H + + + EL L PY +G L +Y+G H +L+ P
Sbjct: 194 THGNLVHNSHLIGLGMELREGSVAVNWLPPYHDMGLIGGILQPLYNGFHGVLLSPITFLQ 253
Query: 696 NPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVVAEERPR 755
P WL A+ +++ +LC + + + + + V C E R
Sbjct: 254 RPLSWLQAIERHRGTCAGGPNFAFDLCVR--KTRPEEREQLDLRTWQVAFC---GAEPIR 308
Query: 756 INLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPSTVYVDLRALRNDRVSL 815
F++ F G P +G I G + T + D RAL++ + +
Sbjct: 309 PETLARFARAFEPAGFRPEFFYPCYGLAEATLIAAGGVKAEPVRTGHFDARALQHGQGAP 368
Query: 816 VERGS-PHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNASGYFTIYGD 874
+ G+ ++ L+ SG LP ++ +P+ + D +GEIW+ P A GY +G
Sbjct: 369 RDEGTGQDTVTLVSSGTQLPTQSLVVVDPQARTLQADGEVGEIWMSGPSVAQGY---WGR 425
Query: 875 ESDYADHFSAQLVTGNTGEVYARTGYLGFLR 905
+ F A+L G + RTG LGFLR
Sbjct: 426 PEETERVFQARLARGE--GPFLRTGDLGFLR 454
Score = 99.5 bits (237), Expect = 4e-19
Identities = 94/390 (24%), Positives = 150/390 (38%), Gaps = 12/390 (3%)
Query: 1 MLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLASVLNGMHVIFIPYALMKVSPAS 60
++ + ++ + EG V L + GL +L + NG H + + P S
Sbjct: 198 LVHNSHLIGLGMELREGSVAVNWLPPYHDMGLIGGILQPLYNGFHGVLLSPITFLQRPLS 257
Query: 61 WMHMITKHRASIAIVKSRDLHWGLLATRDHKEISLSSLRMLLVADGANPWSLSSCDQFLS 120
W+ I +HR + A + + TR + L + GA P + +F
Sbjct: 258 WLQAIERHRGTCAGGPNFAFDLCVRKTRPEEREQLDLRTWQVAFCGAEPIRPETLARFAR 317
Query: 121 VFQSKGVRGDAICPCACSSESMTVCIXXXXXXXXXXXXXVLSMSGLSYGVVRVDAENSLT 180
F+ G R + PC +E+ + G R D
Sbjct: 318 AFEPAGFRPEFFYPCYGLAEATLIAAGGVKAEPVRTGHFDARALQHGQGAPR-DEGTGQD 376
Query: 181 SLTLQDCGQVMPSCVIVVVKMEGPAYLCKTDEVGEICVLSGATGSGYWGLPGLTNTVFRV 240
++TL G +P+ +VVV + L EVGEI + + GYWG P T VF+
Sbjct: 377 TVTLVSSGTQLPTQSLVVVDPQART-LQADGEVGEIWMSGPSVAQGYWGRPEETERVFQA 435
Query: 241 RPLDSDGEPIGEEHYVRSXXXXXXXXXXXXXXXXSRDGLMTVTGRKHNMDDIIATVLAVE 300
R +G ++R+ ++D L+ + GR H D+ T
Sbjct: 436 RLARGEGP------FLRTGDLGFLRDGQLFVTGRAKD-LIIIRGRNHYPQDLEQTTEQSH 488
Query: 301 PMKFIYRGRIAVFSVRVLRDERICIVAEQRPDCGEEESFQWMSRVLQAVDSIHQVGIYCL 360
P I G A FSV V +E + + E E + V QA+ HQ+G++ +
Sbjct: 489 PA--IRPGCSAAFSVDVDGEEHLAVAFEVSAR-QEVSPDDVATSVQQAIAEHHQLGVHAV 545
Query: 361 ALVQPNFLPKTPLGGIHLSECKRRFLEGTL 390
L++ LPKT G I C+ FL+GTL
Sbjct: 546 LLLKAGALPKTSSGKIQRHACRAGFLDGTL 575
Score = 36.7 bits (81), Expect = 3.4
Identities = 35/159 (22%), Positives = 66/159 (41%), Gaps = 13/159 (8%)
Query: 482 SKVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIR 541
S+ LT EL ++A ++ + L G V V + L+L+ + G L G V +
Sbjct: 1182 SETLTYGELDRRANQLAHHLRGLG-VGPEHRVGVCLERSLELVVSLLGVLKAGGAYVPLD 1240
Query: 542 PPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMP 601
P +PQ + ++ + ++L+ Q + K+ + V + P
Sbjct: 1241 PSYPQE------RLDFMLRDAAVRVLLTQQRLAKVFTEAAVTRVFVDADERAPFQHAESP 1294
Query: 602 KKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAV 640
++ A +E LAY+ ++ +TG G +HA V
Sbjct: 1295 RRS------ASWSESLAYVIYTSGSTGRPKGAMNTHAGV 1327
>UniRef50_Q3M1P5 Cluster: Amino acid adenylation; n=2;
Cyanobacteria|Rep: Amino acid adenylation - Anabaena
variabilis (strain ATCC 29413 / PCC 7937)
Length = 2791
Score = 150 bits (363), Expect = 2e-34
Identities = 123/470 (26%), Positives = 203/470 (43%), Gaps = 23/470 (4%)
Query: 444 DDSDAARKYQFIS--QILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLL 501
D + + + +F++ +I+RWR+Q + L + LT EL +A+RI LL
Sbjct: 2 DKNLSQKSVEFVNLLEIIRWRSQKQPQQQAYCFLLDGEVEVQSLTYGELDNQAQRIAGLL 61
Query: 502 LEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDV 561
G V G+ V L++PPGL+ I AF+GCLY GA+ V P +P + +L + +I
Sbjct: 62 QAFG-VKKGERVLLLYPPGLEFITAFFGCLYAGAIAV---PAYPPRANQSLSRLSVIATD 117
Query: 562 SKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKKLPIMYRAPT--AEMLAY 619
+ +T+ L+ +V+ L+ NVL L TD+M ++R P + LA+
Sbjct: 118 ADSTVALTTTTVLSYLQQHPTFNVL------RLLTTDNMMADDWTNLWRQPVIDRDTLAF 171
Query: 620 LDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSI 679
L ++ +TG G+ +SH + +K A + + L + +G L +
Sbjct: 172 LQYTSGSTGTPKGVMVSHGNLLHNQLLIKQAMQHTTATIFVGWLPLFHDMGLVGNMLQPL 231
Query: 680 YSGHHSILIPPSEVEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGIN 739
Y G IL+ P P WL A+SQY+ + +LC + + + ++
Sbjct: 232 YLGIPCILMSPVAFLQKPVRWLQAISQYRATTSGGPNFAYDLCVR----KITAEQRATLD 287
Query: 740 LACVRTCVVVAEERPRINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPS 799
L+ AE + L F+ F G A +G I G + P
Sbjct: 288 LSSWEVAFNGAEPVRQATL-EKFAVTFGECGFRREAFYPCYGMAETTLIVSGGCKTTPPV 346
Query: 800 TVYVDLRALRNDRVSLVERGSPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWV 859
V AL +++ + G + L+ G+ L +K++ +P+T C D +GEIWV
Sbjct: 347 LQPVQSDALAQNQIVPAKAGEIGTQILVGCGQPLADLKIVIVDPQTLSACSDRQVGEIWV 406
Query: 860 QSPHNASGYFTIYGDESDYADHFSAQLVTGNTGEVYARTGYLGFLRRTEI 909
A GY + F A G + RTG LGFL+ E+
Sbjct: 407 AGASVAQGY---WHQPEQTESTFKAYTKDTKEGP-FLRTGDLGFLQDGEL 452
Score = 85.4 bits (202), Expect = 7e-15
Identities = 91/386 (23%), Positives = 159/386 (41%), Gaps = 16/386 (4%)
Query: 7 MLSVACNYTEGEHMVCVLDFKRETGLWHAVLASVLNGMHVIFIPYALMKVSPASWMHMIT 66
++ A +T V L + GL +L + G+ I + P W+ I+
Sbjct: 198 LIKQAMQHTTATIFVGWLPLFHDMGLVGNMLQPLYLGIPCILMSPVAFLQKPVRWLQAIS 257
Query: 67 KHRASIAIVKS--RDLHWGLLATRDHKEISLSSLRMLLVADGANPWSLSSCDQFLSVFQS 124
++RA+ + + DL + + LSS + +GA P ++ ++F F
Sbjct: 258 QYRATTSGGPNFAYDLCVRKITAEQRATLDLSSWEVAF--NGAEPVRQATLEKFAVTFGE 315
Query: 125 KGVRGDAICPCACSSESMTVCIXXXXXXXXXXXXXVLSMSGLSYGVVRVDAENSLTSLTL 184
G R +A PC +E+ T+ + V S + +V A T + L
Sbjct: 316 CGFRREAFYPCYGMAET-TLIVSGGCKTTPPVLQPVQSDALAQNQIVPAKAGEIGTQI-L 373
Query: 185 QDCGQVMPSCVIVVVKMEGPAYLCKTDEVGEICVLSGATGSGYWGLPGLTNTVFRVRPLD 244
CGQ + IV+V + + C +VGEI V + GYW P T + F+ D
Sbjct: 374 VGCGQPLADLKIVIVDPQTLS-ACSDRQVGEIWVAGASVAQGYWHQPEQTESTFKAYTKD 432
Query: 245 SDGEPIGEEHYVRSXXXXXXXXXXXXXXXXSRDGLMTVTGRKHNMDDIIATVLAVEPMKF 304
+ P ++R+ +D L+ + GR + DI TV P
Sbjct: 433 TKEGP-----FLRTGDLGFLQDGELFITGRLKD-LIIIRGRNYYPQDIENTVQQSHPALE 486
Query: 305 IYRGRIAVFSVRVLRDERICIVAE-QRPDCGEEESFQWMSRVLQAVDSIHQVGIYCLALV 363
+ G A FS+ V +ER+ I E QR + + + ++ + AV H++ +Y + L+
Sbjct: 487 PHGG--AAFSIDVDGEERLVIAQEVQRSHIRKLDIDEVIATIRAAVAVNHEIQLYGVLLL 544
Query: 364 QPNFLPKTPLGGIHLSECKRRFLEGT 389
+P + +T G I C+ +FL G+
Sbjct: 545 KPGSILRTSSGKIQRYACRAKFLAGS 570
Score = 41.1 bits (92), Expect = 0.16
Identities = 39/153 (25%), Positives = 69/153 (45%), Gaps = 13/153 (8%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPH 544
LT EL+++A + N L G V VA+ L+ I G L G + + P +
Sbjct: 2282 LTYQELNRRANLLANHLQRLG-VCADTLVAICVERSLEAIVGILGILKAGGAYLPLDPTY 2340
Query: 545 PQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKK 604
P H ++ D + L+ +Q + K+ +K + LDS+ + ++DD P +
Sbjct: 2341 PSE-HLAF----ILKDTQVSLLLTQSQLLPKIPNNKAQTLCLDSEWDIIANNSDDNPSCR 2395
Query: 605 LPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSH 637
T E LAY+ ++ +TG G+ ++H
Sbjct: 2396 T-------TKENLAYVIYTSGSTGNPKGVLITH 2421
Score = 37.5 bits (83), Expect = 1.9
Identities = 14/31 (45%), Positives = 22/31 (70%)
Query: 952 VFVVGALDETIMLRGMRYHPIDIENSVMRCH 982
+F+ G L + I++RG Y+P DIEN+V + H
Sbjct: 452 LFITGRLKDLIIIRGRNYYPQDIENTVQQSH 482
>UniRef50_Q09E86 Cluster: AMP-binding enzyme domain protein; n=1;
Stigmatella aurantiaca DW4/3-1|Rep: AMP-binding enzyme
domain protein - Stigmatella aurantiaca DW4/3-1
Length = 3318
Score = 146 bits (354), Expect = 3e-33
Identities = 129/469 (27%), Positives = 200/469 (42%), Gaps = 24/469 (5%)
Query: 448 AARKYQFISQILRWRAQSTSDHVIFTLLNA---KGAVSKVLTCAELHKKAERIGNLLLEK 504
A R + I +L++RA+ + + L + +GAV + + A L A I L E
Sbjct: 65 APRHHPTIVDLLQFRAREQGSQITYRFLGSGDPEGAVEE-WSLAHLDILARSIAATLQEA 123
Query: 505 GRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKA 564
G+ L++ PGL+ I AF GCLY G V PP P L TLP +R I +A
Sbjct: 124 NA--RGERALLLYAPGLEFIAAFVGCLYAGVTAVPCYPPDPSRLDRTLPRMRAIAQDCEA 181
Query: 565 TLVLSNQSVIKLLRSKEA-SNVLDSKAWPMTLDTDDMPKKKLPIMYRAPTAE--MLAYLD 621
+L+ +++++ + + L W T D L YR P + LA+L
Sbjct: 182 RFILTTTPILEMVGALATYAPELLKVRWIAT----DSTSHDLASAYRRPDLDEGSLAFLQ 237
Query: 622 FSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYS 681
++ +TG G+ +SHA + R +++ E+ S I L + +G L +Y
Sbjct: 238 YTSGSTGTPKGVMVSHANLMHNERMIEMGFEINHSAVIVGWLPMFHDMGLIGQVLQPLYL 297
Query: 682 GHHSILIPPSEVEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLA 741
G L+ P + P WL A+S + + ELC + V + ++L+
Sbjct: 298 GTSVTLMSPLDFLQRPYRWLQAISHLRATVSGGPNFAYELCAR----KVTPEERATLDLS 353
Query: 742 CVRTCVVVAEERPRINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPSTV 801
AE R L FS+ FSA G + +G + + GAS +
Sbjct: 354 SWDVAFTGAEPVRRETL-ERFSETFSACGFRRGSFHACYGL-AEATLFVSGASREARPVI 411
Query: 802 Y-VDLRALRNDRVSLVERGSPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQ 860
+ VD AL+ +V S ++ SG + P ++V NPET C +GEIWV
Sbjct: 412 HAVDKEALQRHQVVEARGEGADSQWMVSSGWIAPELRVEIVNPETSEACRAGEVGEIWVA 471
Query: 861 SPHNASGYFTIYGDESDYADHFSAQLVTGNTGEVYARTGYLGFLRRTEI 909
P A GY +G + F A+L G + RTG LGF E+
Sbjct: 472 GPSVALGY---WGRPEETQQVFHARLANQGAGP-FLRTGDLGFFIGEEL 516
Score = 89.8 bits (213), Expect = 3e-16
Identities = 93/387 (24%), Positives = 157/387 (40%), Gaps = 16/387 (4%)
Query: 6 RMLSVACNYTEGEHMVCVLDFKRETGLWHAVLASVLNGMHVIFIPYALMKVSPASWMHMI 65
RM+ + +V L + GL VL + G V + P W+ I
Sbjct: 261 RMIEMGFEINHSAVIVGWLPMFHDMGLIGQVLQPLYLGTSVTLMSPLDFLQRPYRWLQAI 320
Query: 66 TKHRASIAIVKS--RDLHWGLLATRDHKEISLSSLRMLLVADGANPWSLSSCDQFLSVFQ 123
+ RA+++ + +L + + + LSS + GA P + ++F F
Sbjct: 321 SHLRATVSGGPNFAYELCARKVTPEERATLDLSSWDVAFT--GAEPVRRETLERFSETFS 378
Query: 124 SKGVRGDAICPCACSSESMTVCIXXXXXXXXXXXXXVLSMSGLSYGVVRVDAENSLTSLT 183
+ G R + C +E+ T+ + V + + VV E + S
Sbjct: 379 ACGFRRGSFHACYGLAEA-TLFVSGASREARPVIHAVDKEALQRHQVVEARGEGA-DSQW 436
Query: 184 LQDCGQVMPSCVIVVVKMEGPAYLCKTDEVGEICVLSGATGSGYWGLPGLTNTVFRVRPL 243
+ G + P + +V E + C+ EVGEI V + GYWG P T VF R
Sbjct: 437 MVSSGWIAPELRVEIVNPE-TSEACRAGEVGEIWVAGPSVALGYWGRPEETQQVFHARLA 495
Query: 244 DSDGEPIGEEHYVRSXXXXXXXXXXXXXXXXSRDGLMTVTGRKHNMDDIIATVLAVEPMK 303
+ P ++R+ +D ++ + GR H DI TV P
Sbjct: 496 NQGAGP-----FLRTGDLGFFIGEELFISGRLKD-VIILRGRNHYPQDIEHTVERAHPC- 548
Query: 304 FIYRGRIAVFSVRVLRDERICIVAEQRPDCGEEESFQWMSRVLQAVDSIHQVGIYCLALV 363
+ G A FSV V +E++ + AE + GEE + + +AV H+V ++ +AL+
Sbjct: 549 -VRPGCCAAFSVEVSGEEQLIVAAEVKLH-GEERAATVADAIRRAVADHHEVHVHAVALL 606
Query: 364 QPNFLPKTPLGGIHLSECKRRFLEGTL 390
+P + KT G I C++ +LEG+L
Sbjct: 607 RPGTVLKTTSGKIQRRGCRQLYLEGSL 633
Score = 37.1 bits (82), Expect = 2.6
Identities = 17/45 (37%), Positives = 28/45 (62%), Gaps = 2/45 (4%)
Query: 950 DAVFVVGALDETIMLRGMRYHPIDIENSVMRCHKKIAE--CAVFT 992
+ +F+ G L + I+LRG ++P DIE++V R H + CA F+
Sbjct: 514 EELFISGRLKDVIILRGRNHYPQDIEHTVERAHPCVRPGCCAAFS 558
>UniRef50_Q8YPY3 Cluster: Alr4057 protein; n=5; Cyanobacteria|Rep:
Alr4057 protein - Anabaena sp. (strain PCC 7120)
Length = 602
Score = 146 bits (353), Expect = 4e-33
Identities = 120/457 (26%), Positives = 201/457 (43%), Gaps = 20/457 (4%)
Query: 457 QILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVALI 516
++LR RA D + + L LT AEL + A IG LL+K G+ V L+
Sbjct: 9 ELLRARANHEPDKLAYMFLIDGKTEGPKLTYAELDRLARAIG-ALLQKHNAK-GERVLLL 66
Query: 517 FPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKL 576
+P GLD++ AF G LY G + + PP L LP +R IV + A V +NQ ++ +
Sbjct: 67 YPQGLDVMAAFLGSLYGGVIAIPAPPPDAGRLKRALPRLRAIVKDANAKFVFTNQHLLGV 126
Query: 577 LRSKEAS-NVLDSKAWPMTLDTDDMPKKKLPIMYRAP--TAEMLAYLDFSVSTTGMLAGI 633
L++ + + W + D D +L ++ P T LAYL ++ +T G+
Sbjct: 127 LQAAKLDFPEFEEMTWFASEDID----LELADQWQDPEITPNTLAYLQYTSGSTSTPKGV 182
Query: 634 KMSHAAVTSLCRSMKIACELYPSRHIALCLDPYC-GLGFALWCLSSIYSGHHSILIPPSE 692
+SH + C ++ AC Y + +++ PY G IY+GH ++ P
Sbjct: 183 MISHHNIMHHCAYLQKACG-YDTESVSITWMPYFHDYGLVEGLTVPIYNGHPCYVMSPMS 241
Query: 693 VEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVVAEE 752
P WL A+S+Y+ + E C + + + QL + ++ + V
Sbjct: 242 FIKQPVRWLQAISRYRGTHSQAPNFAYEQCIRRVTDA--QLATLDLS-SWVAAGNAAEPI 298
Query: 753 RPRINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPSTVYVDLRALRNDR 812
PR+ L F K F+ G + ++G N + + P V+ + ++
Sbjct: 299 NPRV-LEEFFEK-FAPSGFKWETFAPAYGLAENTLLVSTSPRNTPPVLCLVEKTKIEQNK 356
Query: 813 VSLVERGSPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNASGYFTIY 872
+ + G+L+ +V NP+T +CG +GE+WV P A GY+
Sbjct: 357 IVEATTWDDGVRAIPGCGRLVCETQVAIVNPDTLTRCGTDEVGEVWVADPSVAGGYWQ-R 415
Query: 873 GDESDYADHFSAQLVTGNTGEVYARTGYLGFLRRTEI 909
ES+ F A+ + GN + RTG LGF++ E+
Sbjct: 416 PQESE--STFRAK-IAGNNQVSFLRTGDLGFIKGGEL 449
Score = 89.0 bits (211), Expect = 6e-16
Identities = 84/393 (21%), Positives = 157/393 (39%), Gaps = 16/393 (4%)
Query: 1 MLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLASVLNGMHVIFI--PYALMKVSP 58
++ HC L AC Y + + + + GL + + NG H ++ P + +K P
Sbjct: 189 IMHHCAYLQKACGYDTESVSITWMPYFHDYGLVEGLTVPIYNG-HPCYVMSPMSFIK-QP 246
Query: 59 ASWMHMITKHRASIAIVKSRDLHWGLLATRDHKEISLSSLRMLLVADGANPWSLSSCDQF 118
W+ I+++R + + + + D + +L + + A P + ++F
Sbjct: 247 VRWLQAISRYRGTHSQAPNFAYEQCIRRVTDAQLATLDLSSWVAAGNAAEPINPRVLEEF 306
Query: 119 LSVFQSKGVRGDAICPCACSSESMTVCIXXXXXXXXXXXXXVLSMSGLSYGVVRVDAENS 178
F G + + P +E+ T+ + V +V +
Sbjct: 307 FEKFAPSGFKWETFAPAYGLAEN-TLLVSTSPRNTPPVLCLVEKTKIEQNKIVEATTWDD 365
Query: 179 LTSLTLQDCGQVMPSCVIVVVKMEGPAYLCKTDEVGEICVLSGATGSGYWGLPGLTNTVF 238
+ CG+++ + +V + C TDEVGE+ V + GYW P + + F
Sbjct: 366 GVR-AIPGCGRLVCETQVAIVNPD-TLTRCGTDEVGEVWVADPSVAGGYWQRPQESESTF 423
Query: 239 RVRPLDSDGEPIGEEHYVRSXXXXXXXXXXXXXXXXSRDGLMTVTGRKHNMDDIIATVLA 298
R + ++ + ++R+ +D L+ + G H D+ TV
Sbjct: 424 RAKIAGNN-----QVSFLRTGDLGFIKGGELFITGRIKD-LIIIRGTNHYPQDLEWTVQE 477
Query: 299 VEPMKFIYRGRIAVFSVRVLRDERICIVAEQRPDCGEE-ESFQWMSRVLQAVDSIHQVGI 357
+ P G A FS+ V E++ +V E + EE S + ++ + QA+ IH++
Sbjct: 478 IHPALRPDYG--AAFSIDVDGVEQLVVVQEVKRKPEEEFNSDEVLTNIRQAIAEIHELQA 535
Query: 358 YCLALVQPNFLPKTPLGGIHLSECKRRFLEGTL 390
Y + LV+P + KT G I CK FL G L
Sbjct: 536 YAVVLVKPGNVLKTSSGKIQRRACKASFLAGEL 568
>UniRef50_Q0B3F8 Cluster: AMP-dependent synthetase and ligase; n=2;
Burkholderia ambifaria|Rep: AMP-dependent synthetase and
ligase - Burkholderia cepacia (strain ATCC 53795 / AMMD)
Length = 1292
Score = 145 bits (351), Expect = 7e-33
Identities = 140/496 (28%), Positives = 228/496 (45%), Gaps = 35/496 (7%)
Query: 429 GNRLASAQGRDMGYTDDSDAARKYQFISQILRWRAQSTSDHVIFTLLNA--KGAVSKVLT 486
G R A+A+ D A +S++L+ RA + D + L+ + ++ +T
Sbjct: 4 GRRQAAARCFHSSSDDIMTTATLPTTLSELLQNRAATLGDKTAYVFLSGPPEQEQAESMT 63
Query: 487 CAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQ 546
AEL +A R+ LL++ ++ GD V L+ PGLD + AF GCLY GA+ V + P P+
Sbjct: 64 FAELDARARRVA-ALLQQNAIDIGDRVLLLCRPGLDYVSAFMGCLYAGAIAVPVYP--PR 120
Query: 547 NLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKKLP 606
N + ++ + T++ S + ++ A+ + D+ A TL + P
Sbjct: 121 NKQHMVRIAGIVENAGANTILCSAED-----HARCATWLADTDASGSTLLDVGGAQVLDP 175
Query: 607 IMYRAPT-AEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIALCLDP 665
+ A +A+L ++ TTG G+ +SH + M+ I L P
Sbjct: 176 VPSPASVQPSRIAFLQYTSGTTGSPKGVMVSHGNLMHNLGLMREWLAYDEQSTIVSWLPP 235
Query: 666 YCGLGFALWCLSSIYSGHHSILIPPSEVEVNPALWLSAVSQYKVRDTFCSYGVMELCTKG 725
Y +G L+S+Y G S+L+ P +P LWL A+SQY+ T +C +
Sbjct: 236 YHDMGLIGVILTSLYGGFRSVLMAPERFIQHPYLWLRAISQYRADLTGAPDFAYRMCCRR 295
Query: 726 LGSSVNQLKSKGINLACVRTCVVVAEERPRINLTNSFSKLFSALGLSPRAVSTSFGCRVN 785
+ S QL + ++L+CVR AE LT+ F++ F+A G + +G
Sbjct: 296 I--SDEQLAT--LDLSCVRVAYNGAESVRASTLTD-FAQRFAAAGFAADGFLPCYGLAEG 350
Query: 786 IAICLQGASSPEP-STVYVDLRALRNDRVSLVERG-----SPHSL------CLMESGKLL 833
+ + G + P T+ VD AL+ R S+V RG SP L L+ G+
Sbjct: 351 -TLYVAGRAKQHPIRTLCVDQAALQ--RQSVVVRGEFLGVSPQPLDRPGERVLVSVGRTD 407
Query: 834 PGVKVITANPETKGQCGDSHLGEIWVQSPHNASGYFTIYGDESDYADHFSAQLVTGNTGE 893
VI + ET +C D +GEI V P A+GY+ + DE ++ F L G+ +
Sbjct: 408 GEQHVIVRDLETNERCADRTIGEICVAGPSVAAGYWHL--DEQTHST-FQHSL-AGHRDQ 463
Query: 894 VYARTGYLGFLRRTEI 909
V+ RTG LGF+ E+
Sbjct: 464 VFMRTGDLGFILGDEL 479
Score = 60.1 bits (139), Expect = 3e-07
Identities = 80/389 (20%), Positives = 152/389 (39%), Gaps = 26/389 (6%)
Query: 14 YTEGEHMVCVLDFKRETGLWHAVLASVLNGMHVIFIPYALMKVSPASWMHMITKHRASIA 73
Y E +V L + GL +L S+ G + + P W+ I+++RA +
Sbjct: 223 YDEQSTIVSWLPPYHDMGLIGVILTSLYGGFRSVLMAPERFIQHPYLWLRAISQYRADLT 282
Query: 74 IVKSRDLHWGLLATR-DHKEISLSSLRMLLVA-DGANPWSLSSCDQFLSVFQSKGVRGDA 131
+ D + + R ++++ L + VA +GA S+ F F + G D
Sbjct: 283 --GAPDFAYRMCCRRISDEQLATLDLSCVRVAYNGAESVRASTLTDFAQRFAAAGFAADG 340
Query: 132 ICPCACSSESMTVCIXXXXXXXXXXXXXVLSMSGLSYGVVRVDAENSLTSLTLQDCGQVM 191
PC +E T+ + V + L V V E ++ Q +
Sbjct: 341 FLPCYGLAEG-TLYVAGRAKQHPIRTLCV-DQAALQRQSVVVRGE--FLGVSPQPLDRPG 396
Query: 192 PSCVIVVVKMEGPAYL----------CKTDEVGEICVLSGATGSGYWGLPGLTNTVFRVR 241
++ V + +G ++ C +GEICV + +GYW L T++ F+
Sbjct: 397 ERVLVSVGRTDGEQHVIVRDLETNERCADRTIGEICVAGPSVAAGYWHLDEQTHSTFQ-H 455
Query: 242 PLDSDGEPIGEEHYVRSXXXXXXXXXXXXXXXXSRDGLMTVTGRKHNMDDIIATVLAVEP 301
L + + ++R+ +D ++ + GR + +DI ++ P
Sbjct: 456 SLAGHRDQV----FMRTGDLGFILGDELYVTGRLKD-MVILAGRNYYSEDIEYALIVGVP 510
Query: 302 MKFIYRGRIAVFSVRVLRDERICIVAEQRPDCGEEESFQWMSRVLQAVDSIHQVGIYCLA 361
+ + G A F + ER+ +VAE + ++ + QA+ + +G +
Sbjct: 511 -ELVPNG-CAAFMDDQVDAERLIVVAEVERTQRKGNLDSFIDAIRQAIWNRLDIGPSAIV 568
Query: 362 LVQPNFLPKTPLGGIHLSECKRRFLEGTL 390
LV P +PKT G + S C+ + +G L
Sbjct: 569 LVSPGSVPKTSSGKVRRSTCRTQLHDGAL 597
>UniRef50_Q3M5M8 Cluster: Beta-ketoacyl synthase; n=4; Bacteria|Rep:
Beta-ketoacyl synthase - Anabaena variabilis (strain
ATCC 29413 / PCC 7937)
Length = 1656
Score = 144 bits (349), Expect = 1e-32
Identities = 121/463 (26%), Positives = 206/463 (44%), Gaps = 24/463 (5%)
Query: 451 KYQFISQILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTG 510
++ + +LR+RAQ+ +T L S LT EL +KA I LL++G G
Sbjct: 8 EFSTLVDLLRYRAQNQPTQTAYTFLVDGETESISLTYQELDQKARAIATQLLQRGV--PG 65
Query: 511 DHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSN 570
L++PPG++ I AF+GCLY G + V P +P + + ++ IV ++A + L+
Sbjct: 66 SRALLLYPPGMEFIPAFFGCLYAGFIAV---PAYPPRRNQKMSRLQAIVSDAEAVVALTT 122
Query: 571 QSVIKLLRSKEASN-VLDSKAWPMTLDTDDMPKKKLPIMYRAP--TAEMLAYLDFSVSTT 627
+ + + + A N L + W + TD++ + ++ P ++ LA+L ++ +T
Sbjct: 123 STELTSMALQLAENPTLTAIPW---ITTDNL-NANIAEDWQQPNINSDTLAFLQYTSGST 178
Query: 628 GMLAGIKMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSIL 687
G G+ ++H + + + + P+ + L PY +G L +Y G L
Sbjct: 179 GTPKGVMITHGNLLHNSQLIYNFYQHTPNSQGVIWLPPYHDMGLIGGVLQPLYGGFPVTL 238
Query: 688 IPPSEVEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCV 747
+ P P WL A+S YK + +L + + + QL S ++L+
Sbjct: 239 MAPVAFLQKPFRWLQAISHYKATTSGGPDFAYDLVCRQI--TPEQLAS--LDLSSWEVAF 294
Query: 748 VVAEERPRINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPSTVYVDLRA 807
AE R + F++ F+ G A +G I G S P ++D A
Sbjct: 295 TGAEP-IRAQTLDRFAETFAPCGFRREAFYPCYGMAETTLIVSGGWKSEAPIVRHIDTTA 353
Query: 808 LRNDRVSLVERGSPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNASG 867
L ++V + + ++ GK P V+ NPE+ C D +GEIWV A G
Sbjct: 354 LLQNQV-IDTTTAAGGKAIVGCGKSSPDQTVLIVNPESLTSCADGQVGEIWVSGSSVAQG 412
Query: 868 YFTIYGDESDYADH-FSAQLVTGNTGEVYARTGYLGFLRRTEI 909
Y+ + + H F A L TG + RTG LGFL+ E+
Sbjct: 413 YW----NRPEQTQHTFHAYLADNTTGP-FLRTGDLGFLQDGEL 450
Score = 88.2 bits (209), Expect = 1e-15
Identities = 90/366 (24%), Positives = 145/366 (39%), Gaps = 19/366 (5%)
Query: 29 ETGLWHAVLASVLNGMHV-IFIPYALMKVSPASWMHMITKHRASIAIVK--SRDLHWGLL 85
+ GL VL + G V + P A ++ P W+ I+ ++A+ + + DL +
Sbjct: 219 DMGLIGGVLQPLYGGFPVTLMAPVAFLQ-KPFRWLQAISHYKATTSGGPDFAYDLVCRQI 277
Query: 86 ATRDHKEISLSSLRMLLVADGANPWSLSSCDQFLSVFQSKGVRGDAICPCACSSESMTVC 145
+ LSS + GA P + D+F F G R +A PC +E T
Sbjct: 278 TPEQLASLDLSSWEVAFT--GAEPIRAQTLDRFAETFAPCGFRREAFYPCYGMAE--TTL 333
Query: 146 IXXXXXXXXXXXXXVLSMSGLSYGVVRVDAENSLTSLTLQDCGQVMPSCVIVVVKMEGPA 205
I + + L V +D + + CG+ P +++V E
Sbjct: 334 IVSGGWKSEAPIVRHIDTTALLQNQV-IDTTTAAGGKAIVGCGKSSPDQTVLIVNPESLT 392
Query: 206 YLCKTDEVGEICVLSGATGSGYWGLPGLTNTVFRVRPLDSDGEPIGEEHYVRSXXXXXXX 265
C +VGEI V + GYW P T F D+ P ++R+
Sbjct: 393 S-CADGQVGEIWVSGSSVAQGYWNRPEQTQHTFHAYLADNTTGP-----FLRTGDLGFLQ 446
Query: 266 XXXXXXXXXSRDGLMTVTGRKHNMDDIIATVLAVEPMKFIYRGRIAVFSVRVLRDERICI 325
+D L+ + GR H DI TV + P G A F+V V E++ I
Sbjct: 447 DGELFITGRLKD-LIIIMGRNHYPQDIEFTVESCHPALRPAGG--AAFAVEVNNVEKLVI 503
Query: 326 VAE-QRPDCGEEESFQWMSRVLQAVDSIHQVGIYCLALVQPNFLPKTPLGGIHLSECKRR 384
V E +R + + + + + +AV H + + +AL++ N LPKT G + S CK
Sbjct: 504 VQEVERSYLRKLNADEVIGAIRKAVAEHHDLQTHTIALIKTNSLPKTSSGKVRRSNCKAE 563
Query: 385 FLEGTL 390
G+L
Sbjct: 564 LEAGSL 569
>UniRef50_UPI000045BBBF Cluster: COG0318: Acyl-CoA synthetases
(AMP-forming)/AMP-acid ligases II; n=2; Nostoc
punctiforme PCC 73102|Rep: COG0318: Acyl-CoA synthetases
(AMP-forming)/AMP-acid ligases II - Nostoc punctiforme
PCC 73102
Length = 1178
Score = 141 bits (342), Expect = 8e-32
Identities = 118/459 (25%), Positives = 197/459 (42%), Gaps = 24/459 (5%)
Query: 455 ISQILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVA 514
+ ILR R+ + FT L LT EL +++ I + L G +G+
Sbjct: 18 VVDILRDRSSTQPHTQAFTFLEDGETQESTLTYYELDRRSRAIASQLQALGL--SGERAI 75
Query: 515 LIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVI 574
L++PPGLD + AF+GCLY G V V PP Q P ++ I+ ++A ++L+ +++
Sbjct: 76 LLYPPGLDYLTAFFGCLYAGVVAVPAYPPRNQR---NTPRIQAIIADAQAAIILTTTTLL 132
Query: 575 KLLRSKEASNV-LDSKAWPMTLDTDDMPKKKLPIMYRAP--TAEMLAYLDFSVSTTGMLA 631
++S + S W L TD++ + + ++ P A++LA+L ++ +TG
Sbjct: 133 PNVKSLLTKHTDQGSLCW---LTTDNL-AQGIEDSWQQPEIDAQILAFLQYTSGSTGTPK 188
Query: 632 GIKMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIPPS 691
G+ +SH + E P L Y +G L +Y G +L+ P+
Sbjct: 189 GVMLSHGNLLHNAAVTYQIMEHSPESQFVSWLPVYHDMGLIGGILQPLYGGFPCVLMSPT 248
Query: 692 EVEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVVAE 751
P WL A+SQY+ + ELC + + + ++L+ AE
Sbjct: 249 SFLQRPYRWLQAISQYRGTTSGGPNFAYELCIQ----RITPEQKSTLDLSSWSVAFNGAE 304
Query: 752 ERPRINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPSTVYVDLRALRND 811
R FS F+ G P +G + G P V AL +
Sbjct: 305 P-IRSETLERFSATFAECGFRPEGFYPCYGMAEATLMVSGGIKKALPPCKTVAKSAL--E 361
Query: 812 RVSLVERGSPHSL-CLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNASGYFT 870
R ++E + + + G+ +P +++ A+PET C +GEIWV P GY+
Sbjct: 362 RHQVIEAATSEDIQTFVSCGQSVPQQQIVIAHPETLKPCQPDEVGEIWVSGPSIGQGYWN 421
Query: 871 IYGDESDYADHFSAQLVTGNTGEVYARTGYLGFLRRTEI 909
DE+ H S + G ++ RTG LGFL + E+
Sbjct: 422 -RPDETKQTFHAS---LKGPDSRLFLRTGDLGFLDKGEL 456
Score = 83.4 bits (197), Expect = 3e-14
Identities = 91/396 (22%), Positives = 155/396 (39%), Gaps = 19/396 (4%)
Query: 1 MLAHCRML-SVACNYTEGEH-----MVCVLDFKRETGLWHAVLASVLNGMHVIFIPYALM 54
ML+H +L + A Y EH V L + GL +L + G + +
Sbjct: 191 MLSHGNLLHNAAVTYQIMEHSPESQFVSWLPVYHDMGLIGGILQPLYGGFPCVLMSPTSF 250
Query: 55 KVSPASWMHMITKHRASIAIVKSRDLHWGLLATRDHKEISLSSLRMLLVADGANPWSLSS 114
P W+ I+++R + + + + ++ +L + +GA P +
Sbjct: 251 LQRPYRWLQAISQYRGTTSGGPNFAYELCIQRITPEQKSTLDLSSWSVAFNGAEPIRSET 310
Query: 115 CDQFLSVFQSKGVRGDAICPCACSSESMTVCIXXXXXXXXXXXXXVLSMSGLSYGVVRVD 174
++F + F G R + PC +E+ T+ + V + S L V ++
Sbjct: 311 LERFSATFAECGFRPEGFYPCYGMAEA-TLMVSGGIKKALPPCKTV-AKSALERHQV-IE 367
Query: 175 AENSLTSLTLQDCGQVMPSCVIVVVKMEGPAYLCKTDEVGEICVLSGATGSGYWGLPGLT 234
A S T CGQ +P IV+ E C+ DEVGEI V + G GYW P T
Sbjct: 368 AATSEDIQTFVSCGQSVPQQQIVIAHPE-TLKPCQPDEVGEIWVSGPSIGQGYWNRPDET 426
Query: 235 NTVFRVRPLDSDGEPIGEEHYVRSXXXXXXXXXXXXXXXXSRDGLMTVTGRKHNMDDIIA 294
F D ++R+ ++D L+ + GR D+
Sbjct: 427 KQTFHASLKGPD-----SRLFLRTGDLGFLDKGELFITGRAKD-LIIIRGRNLYPQDLEL 480
Query: 295 TVLAVEPMKFIYRGRIAVFSVRVLRDERICIVAEQRPDCGEEESFQWMSRVLQAVDSIHQ 354
TV + G A FSV +ER+ +V ++ + + ++ + QAV ++
Sbjct: 481 TV--ERSHSSLRSGSGAAFSVEAENEERL-VVVQELEFRAKPNIEEVIAAIRQAVAEEYE 537
Query: 355 VGIYCLALVQPNFLPKTPLGGIHLSECKRRFLEGTL 390
+ +Y + L++P +PKT G I K FL L
Sbjct: 538 IQVYAVVLIKPGTIPKTSSGKIQRRATKADFLANKL 573
>UniRef50_Q4SNK4 Cluster: Chromosome 15 SCAF14542, whole genome
shotgun sequence; n=3; Tetraodontidae|Rep: Chromosome 15
SCAF14542, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 405
Score = 140 bits (339), Expect = 2e-31
Identities = 68/133 (51%), Positives = 87/133 (65%), Gaps = 1/133 (0%)
Query: 109 PWSLSSCDQFLSVFQSKGVRGDAICPCACSSESMTVCIXXXXXXXXX-XXXXVLSMSGLS 167
P S+SSCD FL+VFQSKG+R + CPCA S E++TV I VLS LS
Sbjct: 70 PGSISSCDAFLNVFQSKGLRSEVRCPCASSPEALTVAIRRYTLTHRACGGRGVLSTQDLS 129
Query: 168 YGVVRVDAENSLTSLTLQDCGQVMPSCVIVVVKMEGPAYLCKTDEVGEICVLSGATGSGY 227
+GV+R+D+E L+ LTLQD G VMP ++ VK EG LCK DE GE+ V + ATG+ Y
Sbjct: 130 HGVIRIDSEEKLSVLTLQDVGSVMPGALMCTVKAEGLPLLCKADETGELVVCTVATGTSY 189
Query: 228 WGLPGLTNTVFRV 240
+GLPG+T T+F V
Sbjct: 190 YGLPGMTKTMFEV 202
Score = 60.5 bits (140), Expect = 2e-07
Identities = 26/43 (60%), Positives = 35/43 (81%)
Query: 70 ASIAIVKSRDLHWGLLATRDHKEISLSSLRMLLVADGANPWSL 112
A +A V SRD+HW +A RD ++++LSSLRMLLVADG+NP+ L
Sbjct: 1 AKVACVTSRDMHWAPVAHRDQRDVNLSSLRMLLVADGSNPFPL 43
>UniRef50_A5IE32 Cluster: Saframycin Mx1 synthetase B; n=4;
Legionella pneumophila|Rep: Saframycin Mx1 synthetase B
- Legionella pneumophila (strain Corby)
Length = 581
Score = 140 bits (338), Expect = 2e-31
Identities = 122/458 (26%), Positives = 200/458 (43%), Gaps = 18/458 (3%)
Query: 453 QFISQILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDH 512
Q + ++R RA + T LN + + + +T +L A+ I L KG GD
Sbjct: 9 QSLVDVVRLRALHSPKKKSCTFLNKE--LEETMTYEQLDLHAKAIAATLQAKG-AKPGDR 65
Query: 513 VALIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQS 572
V L+F PGL LI AF GCLY G + V I PP + L L + IV SK +VL
Sbjct: 66 VLLLFAPGLPLIQAFLGCLYAGCIAVPIYPPAQEKL---LDKAQRIVTNSKPVIVLMIAD 122
Query: 573 VIKLLRSKEA-SNVLDSKAWPMTLDTDDMPKKKLPIMYRAPTAEMLAYLDFSVSTTGMLA 631
IK + E +N K + L++ ++ + + + +A+L ++ +T
Sbjct: 123 HIKKFTADELNTNPQFLKIPAIALESIEL-NRSSSWQPTSIKSNDIAFLQYTSGSTMHPK 181
Query: 632 GIKMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIPPS 691
G+ +SH + + + + I L P+ +G L+ IY G +I++ P
Sbjct: 182 GVMVSHHNLLDNLGKIFTSFHMNDETIIFSWLPPHHDMGLIGCILTPIYGGIQAIMMSPF 241
Query: 692 EVEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVVAE 751
NP WL +++Y+ + + C K + + K +G++L+ T AE
Sbjct: 242 SFLQNPLSWLKHITKYRATISGSPNFAYDYCVK----RIREEKKEGLDLSSWVTAFNGAE 297
Query: 752 ERPRINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPSTVYVDLRALRND 811
R F + F G A +G + G T+ + ++
Sbjct: 298 P-VRAETMEHFYQAFKDYGFRKEAFYPCYGLAEATLLVTGGTPGNPYKTLTLAKEQFQDH 356
Query: 812 RVSLVERGSPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNASGYFTI 871
RV + SP S L+ SG + VK+I +P+T C +GEIWVQS A GY+
Sbjct: 357 RVHFADDNSPGSYKLVSSGNPIQAVKII--DPDTLIPCDFDQVGEIWVQSNSVAKGYWN- 413
Query: 872 YGDESDYADHFSAQLVTGNTGEVYARTGYLGFLRRTEI 909
+E+ +A F+ ++ + +Y RTG LGFL E+
Sbjct: 414 QPEETKHA--FAGKIKDDESSAIYLRTGDLGFLHENEL 449
Score = 89.4 bits (212), Expect = 5e-16
Identities = 82/367 (22%), Positives = 156/367 (42%), Gaps = 21/367 (5%)
Query: 29 ETGLWHAVLASVLNGMHVIFI-PYALMKVSPASWMHMITKHRASIAIVKSRDLHWGLLAT 87
+ GL +L + G+ I + P++ ++ +P SW+ ITK+RA+I+ + + +
Sbjct: 218 DMGLIGCILTPIYGGIQAIMMSPFSFLQ-NPLSWLKHITKYRATISGSPNFAYDYCVKRI 276
Query: 88 RDHKEISLSSLRMLLVADGANPWSLSSCDQFLSVFQSKGVRGDAICPCACSSESMTVCIX 147
R+ K+ L + +GA P + + F F+ G R +A PC +E+ T+ +
Sbjct: 277 REEKKEGLDLSSWVTAFNGAEPVRAETMEHFYQAFKDYGFRKEAFYPCYGLAEA-TLLVT 335
Query: 148 XXXXXXXXXXXXVLSMSGLSYGVVRVDAENSLTSLTLQDCGQVMPSCVIVVVKMEGPAYL 207
+ + V D +NS S L G + + I+ P
Sbjct: 336 GGTPGNPYKTLTLAKEQFQDHRVHFAD-DNSPGSYKLVSSGNPIQAVKIIDPDTLIP--- 391
Query: 208 CKTDEVGEICVLSGATGSGYWGLPGLTNTVFRVRPLDSDGEPIGEEHYVRSXXXXXXXXX 267
C D+VGEI V S + GYW P T F + D + I Y+R+
Sbjct: 392 CDFDQVGEIWVQSNSVAKGYWNQPEETKHAFAGKIKDDESSAI----YLRTGDLGFLHEN 447
Query: 268 XXXXXXXSRDGLMTVTGRKHNMDDIIATVLAVEPMKFIYRGRIAVFSVRVLRDERICIVA 327
+D L+ + G+ H DI +++ P+ + G+ A F ++ + ++ ++
Sbjct: 448 ELYVTGRIKD-LIIIYGKNHYPQDIEFSLMH-SPLHHVL-GKCAAFVIQEEHEYKLTVMC 504
Query: 328 EQR----PDCGEEESFQWMSRVLQAVDSIHQVGIYCLALVQPNFLPKTPLGGIHLSECKR 383
E + D ++ F + + + V HQ+ ++ + L+ +P T G I + C++
Sbjct: 505 EVKNRFMDDVAQDNLF---NEIFELVYENHQLEVHTIVLIPLKAMPHTTSGKIRRNFCRK 561
Query: 384 RFLEGTL 390
L+ TL
Sbjct: 562 HLLDKTL 568
>UniRef50_Q113H9 Cluster: AMP-dependent synthetase and ligase; n=2;
Cyanobacteria|Rep: AMP-dependent synthetase and ligase -
Trichodesmium erythraeum (strain IMS101)
Length = 991
Score = 137 bits (331), Expect = 2e-30
Identities = 105/403 (26%), Positives = 171/403 (42%), Gaps = 18/403 (4%)
Query: 510 GDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLS 569
G+ V L++PPGL L+ F+GCLY GA+ + PP P +L + I ++A L+L+
Sbjct: 59 GERVLLLYPPGLKLMAGFFGCLYGGAIAIPTYPPRPDQ---SLSKLEAIAADAQAKLILT 115
Query: 570 NQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKKLPIMYRAPT--AEMLAYLDFSVSTT 627
++ L+ + A N + A LDTD++ + L ++ P + LA+L ++ +T
Sbjct: 116 TTPLLPYLKGRFAENPM--LATIQLLDTDNIIAQNLESHWQEPNINGDTLAFLQYTSGST 173
Query: 628 GMLAGIKMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSIL 687
G G+ ++H + ++ P L G + L +Y +
Sbjct: 174 GKPKGVMITHKNILHNLAMGYEQSDITPESITVTWLPFSHNTGLLVGVLQPLYGNFPVKI 233
Query: 688 IPPSEVEVNPALWLSAVSQYKVRDTFCSYGVMEL-CTKGLGSSVNQLKSKGINLACVRTC 746
+ P + P WL A+S YK + +L C + L LA
Sbjct: 234 MSPLDFLQKPFRWLMAMSHYKATQSLAPNFAYDLVCFQTTPEERAMLDLSNWELALSGAE 293
Query: 747 VVVAEERPRINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPSTVYVDLR 806
+ AE R F K F G P A++ +G ++ G + P + VD
Sbjct: 294 PIRAETFER------FIKTFKPYGFRPEALTAGYGMAESVVGITLGLITEPPVILNVDKA 347
Query: 807 ALRNDRVSLVERGSPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNAS 866
+RV + + + ++ G+ G K++ NPET +C D +GEIWV SP A
Sbjct: 348 EFTKNRVLVTVDENDSTQKIVSCGRASSGEKILIVNPETLTECADDQVGEIWVSSPSVAQ 407
Query: 867 GYFTIYGDESDYADHFSAQLVTGNTGEVYARTGYLGFLRRTEI 909
GY + A+ F L G + RTG LGFL E+
Sbjct: 408 GY---WSRPQATAETFQNYLKDTQEGP-FLRTGDLGFLLNDEL 446
Score = 78.6 bits (185), Expect = 8e-13
Identities = 91/369 (24%), Positives = 144/369 (39%), Gaps = 14/369 (3%)
Query: 24 LDFKRETGLWHAVLASVLNGMHV-IFIPYALMKVSPASWMHMITKHRASIAIVKSRDLHW 82
L F TGL VL + V I P ++ P W+ ++ ++A+ ++ +
Sbjct: 209 LPFSHNTGLLVGVLQPLYGNFPVKIMSPLDFLQ-KPFRWLMAMSHYKATQSLAPNFAYDL 267
Query: 83 GLLATRDHKEISLSSLRMLLVADGANPWSLSSCDQFLSVFQSKGVRGDAICPCACSSESM 142
T + L L GA P + ++F+ F+ G R +A+ +ES+
Sbjct: 268 VCFQTTPEERAMLDLSNWELALSGAEPIRAETFERFIKTFKPYGFRPEALTAGYGMAESV 327
Query: 143 TVCIXXXXXXXXXXXXXVLSMSGLSYGVVRVDAENSLTSLTLQDCGQVMPSCVIVVVKME 202
V I V V+ EN T + CG+ I++V E
Sbjct: 328 -VGITLGLITEPPVILNVDKAEFTKNRVLVTVDENDSTQ-KIVSCGRASSGEKILIVNPE 385
Query: 203 GPAYLCKTDEVGEICVLSGATGSGYWGLPGLTNTVFRVRPLDSDGEPIGEEHYVRSXXXX 262
C D+VGEI V S + GYW P T F+ D+ P ++R+
Sbjct: 386 TLTE-CADDQVGEIWVSSPSVAQGYWSRPQATAETFQNYLKDTQEGP-----FLRTGDLG 439
Query: 263 XXXXXXXXXXXXSRDGLMTVTGRKHNMDDIIATVLAVEPMKFIYRGRIAVFSVRVLRDER 322
+D L+ + G H DI TV G A FSV + +ER
Sbjct: 440 FLLNDELFVTGRLKD-LIIIRGSNHYPQDIELTVDRSHQALRPSCG--AAFSVELESEER 496
Query: 323 ICIVAE-QRPDCGEEESFQWMSRVLQAVDSIHQVGIYCLALVQPNFLPKTPLGGIHLSEC 381
+ IV E Q + + + ++ + QAV HQ+ +Y + L++ +PKT I C
Sbjct: 497 LVIVQEVQESYLDKLDVDEVVNAIRQAVSQQHQLQVYGILLLKTGTIPKTSSNKIQRHAC 556
Query: 382 KRRFLEGTL 390
K FLE +L
Sbjct: 557 KVGFLEQSL 565
Score = 35.9 bits (79), Expect = 5.9
Identities = 15/37 (40%), Positives = 25/37 (67%)
Query: 949 HDAVFVVGALDETIMLRGMRYHPIDIENSVMRCHKKI 985
+D +FV G L + I++RG ++P DIE +V R H+ +
Sbjct: 443 NDELFVTGRLKDLIIIRGSNHYPQDIELTVDRSHQAL 479
>UniRef50_A3IW78 Cluster: Beta-ketoacyl synthase; n=2;
Cyanobacteria|Rep: Beta-ketoacyl synthase - Cyanothece
sp. CCY 0110
Length = 632
Score = 135 bits (327), Expect = 5e-30
Identities = 111/454 (24%), Positives = 198/454 (43%), Gaps = 20/454 (4%)
Query: 458 ILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIF 517
+LR+RA + +T L S LT EL +A+ I +L G +G+ L++
Sbjct: 34 LLRYRAINQPHQKAYTFLKDGETESISLTYEELDLEAKNIATKMLLLGV--SGERALLLY 91
Query: 518 PPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLL 577
PPG++ I AF+GCLY +P+ + PP + L ++ +V + A + L+ Q+++ +
Sbjct: 92 PPGIEFITAFFGCLYASIIPIPLYPP---KRNQNLLRLQSVVADAGAKIALTTQNILDNI 148
Query: 578 RSKEASNVLDSKAWPMTLDTDDMPKKKLPIMYRAP--TAEMLAYLDFSVSTTGMLAGIKM 635
K N D A + T D ++ L + P ++ LA+L ++ +TG G+ +
Sbjct: 149 -EKHFVNTPDLAA--LNWFTTDNYEENLAESWYPPKISSHSLAFLQYTSGSTGNPKGVMV 205
Query: 636 SHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIPPSEVEV 695
+H + + + I L + +G L +Y G ++ P+
Sbjct: 206 THENLLINSADLDQGWQHTSDSVIVTWLPTFHDMGLIYGVLQPLYKGIPCYMMSPATFLQ 265
Query: 696 NPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVVAEERPR 755
+P WL A+S YK + ELC + + + + ++L+ + + AE R
Sbjct: 266 SPVRWLQAISHYKGTHSAAPNFAYELCAR----KITPEQKETLDLSSWKMALNGAEP-VR 320
Query: 756 INLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPSTVYVDLRALRNDRVSL 815
++ F+K FS+ G A +G ++ EP+ V AL+ ++V
Sbjct: 321 ADVLERFAKAFSSCGFKATAFCPGYGLAEATLKVAAVRTTEEPTLYRVQTDALQENKVVE 380
Query: 816 VERGSPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNASGYFTIYGDE 875
+ + L+ G +++ NP+T C +GEIWV A GY + E
Sbjct: 381 AQPQDENQQVLVGCGTTEIDTRIVIVNPDTLTPCAADEVGEIWVSGQTVAQGY---WQRE 437
Query: 876 SDYADHFSAQLVTGNTGEVYARTGYLGFLRRTEI 909
+ A F A+L G + RTG LGF + E+
Sbjct: 438 VETAKTFQAKLANGE--GTFLRTGDLGFFKDGEL 469
Score = 64.1 bits (149), Expect = 2e-08
Identities = 78/330 (23%), Positives = 124/330 (37%), Gaps = 16/330 (4%)
Query: 1 MLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLASVLNGMHVIFIPYALMKVSPAS 60
+L + L +T +V L + GL + VL + G+ + A SP
Sbjct: 210 LLINSADLDQGWQHTSDSVIVTWLPTFHDMGLIYGVLQPLYKGIPCYMMSPATFLQSPVR 269
Query: 61 WMHMITKHRA--SIAIVKSRDLHWGLLATRDHKEISLSSLRMLLVADGANPWSLSSCDQF 118
W+ I+ ++ S A + +L + + + LSS +M L +GA P ++F
Sbjct: 270 WLQAISHYKGTHSAAPNFAYELCARKITPEQKETLDLSSWKMAL--NGAEPVRADVLERF 327
Query: 119 LSVFQSKGVRGDAICPCACSSESMTVCIXXXXXXXXXXXXXVLSMSGLSYGVVRVDAENS 178
F S G + A CP +E+ T+ + V + + VV ++
Sbjct: 328 AKAFSSCGFKATAFCPGYGLAEA-TLKVAAVRTTEEPTLYRVQTDALQENKVVEAQPQDE 386
Query: 179 LTSLTLQDCGQVMPSCVIVVVKMEGPAYLCKTDEVGEICVLSGATGSGYWGLPGLTNTVF 238
L CG IV+V + C DEVGEI V GYW T F
Sbjct: 387 -NQQVLVGCGTTEIDTRIVIVNPD-TLTPCAADEVGEIWVSGQTVAQGYWQREVETAKTF 444
Query: 239 RVRPLDSDGEPIGEEHYVRSXXXXXXXXXXXXXXXXSRDGLMTVTGRKHNMDDIIATVLA 298
+ + + GE ++R+ +D ++ + GR H DI TV
Sbjct: 445 QAKLAN------GEGTFLRTGDLGFFKDGELFVTGRLKD-VLIIRGRNHYPQDIEMTVEQ 497
Query: 299 VEPMKFIYRGRIAVFSVRVLRDERICIVAE 328
I R A F+V V E++ I AE
Sbjct: 498 CHDA--IVNNRSAAFTVEVNGKEKLVITAE 525
Score = 36.7 bits (81), Expect = 3.4
Identities = 17/43 (39%), Positives = 26/43 (60%), Gaps = 2/43 (4%)
Query: 952 VFVVGALDETIMLRGMRYHPIDIENSVMRCHKKIA--ECAVFT 992
+FV G L + +++RG ++P DIE +V +CH I A FT
Sbjct: 469 LFVTGRLKDVLIIRGRNHYPQDIEMTVEQCHDAIVNNRSAAFT 511
>UniRef50_Q2T3X5 Cluster: AMP-binding domain protein; n=10;
pseudomallei group|Rep: AMP-binding domain protein -
Burkholderia thailandensis (strain E264 / ATCC 700388 /
DSM 13276 /CIP 106301)
Length = 1323
Score = 133 bits (322), Expect = 2e-29
Identities = 131/473 (27%), Positives = 209/473 (44%), Gaps = 41/473 (8%)
Query: 455 ISQILRWRAQSTSDHVIFTLLNAK--GAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDH 512
I+++LR RA + + V + L+ + + +T AEL A R+ L+L++ V G+
Sbjct: 34 INELLRVRAATRGEKVAYLFLSGQPDDEQRQSITFAELELSARRVA-LMLQRQSVGIGER 92
Query: 513 VALIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSN-- 570
V L+ PGLD I F GCLY GAV V PP + H + V IV+ + A +LS
Sbjct: 93 VLLLCRPGLDYIAGFLGCLYAGAVAVPAYPPRNRQ-HAS--RVVGIVESAGAKAILSTGD 149
Query: 571 --QSVIKLLRSKEASNV--LDSKAWPMTLDTDDMPKKKLPIMYRAPTAEMLAYLDFSVST 626
KLL AS+V LD A LD P P +A+L ++ T
Sbjct: 150 DFARCTKLLEDTAASHVALLDLDA-AKPLDATFEPADVAP--------SHIAFLQYTSGT 200
Query: 627 TGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSI 686
TG G+ ++H + + + + L PY +G L+S++ G +
Sbjct: 201 TGKPKGVMVTHGNLIHNLALIGEWMGYHEESTMVSWLPPYHDMGLIGGILTSLFGGFRCV 260
Query: 687 LIPPSEVEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTC 746
L+ P +P LWL A+S Y+ T +C++ + QL + ++L+C++T
Sbjct: 261 LMAPERFIQHPFLWLRAISDYRADVTGAPDFAYRMCSRRVPD--EQLAT--LDLSCLKTA 316
Query: 747 VVVAEERPRINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEP-STVYVDL 805
AE R F++ F+ G P +G + + G S+P P TV VD
Sbjct: 317 YSGAES-VRYGTLAEFAQRFAPAGFDPLRFKPCYGL-AECTLLVAGRSAPRPLRTVCVDQ 374
Query: 806 RALRNDRVSL---VERGSPHS------LCLMESGKLLPGVKVITANPETKGQCGDSHLGE 856
AL+ +V + E +P + L+ G + +V+ + T +C D +GE
Sbjct: 375 AALQQQKVVIRRAFEGLAPQTDERDGERVLVSVGVPIGEQRVVVRDLNTNERCADDEIGE 434
Query: 857 IWVQSPHNASGYFTIYGDESDYADHFSAQLVTGNTGEVYARTGYLGFLRRTEI 909
I V A GY+ Y E A + + G G+ +A TG LGF R ++
Sbjct: 435 ICVAGASVAPGYWQQY--EQTLATF--QRGIGGEAGQEFAGTGDLGFYHRGDL 483
Score = 66.9 bits (156), Expect = 3e-09
Identities = 88/386 (22%), Positives = 150/386 (38%), Gaps = 20/386 (5%)
Query: 14 YTEGEHMVCVLDFKRETGLWHAVLASVLNGMHVIFIPYALMKVSPASWMHMITKHRASIA 73
Y E MV L + GL +L S+ G + + P W+ I+ +RA +
Sbjct: 227 YHEESTMVSWLPPYHDMGLIGGILTSLFGGFRCVLMAPERFIQHPFLWLRAISDYRADVT 286
Query: 74 IVKSRDLHWGLLATR-DHKEISLSSLRMLLVA-DGANPWSLSSCDQFLSVFQSKGVRGDA 131
+ D + + + R ++++ L L A GA + +F F G
Sbjct: 287 --GAPDFAYRMCSRRVPDEQLATLDLSCLKTAYSGAESVRYGTLAEFAQRFAPAGFDPLR 344
Query: 132 ICPCACSSESMTVCIXXXXXXXXXXXXXVLSMSGLSYGVVRVDAENSLTSLTLQDCGQ-V 190
PC +E T+ + V + VV A L T + G+ V
Sbjct: 345 FKPCYGLAEC-TLLVAGRSAPRPLRTVCVDQAALQQQKVVIRRAFEGLAPQTDERDGERV 403
Query: 191 MPSCVI------VVVKMEGPAYLCKTDEVGEICVLSGATGSGYWGLPGLTNTVFRVRPLD 244
+ S + VVV+ C DE+GEICV + GYW T F+ R +
Sbjct: 404 LVSVGVPIGEQRVVVRDLNTNERCADDEIGEICVAGASVAPGYWQQYEQTLATFQ-RGI- 461
Query: 245 SDGEPIGEEHYVRSXXXXXXXXXXXXXXXXSRDGLMTVTGRKHNMDDIIATVLAVEPMKF 304
G G+E + + +D ++ + GR + +D+ V+ P +
Sbjct: 462 --GGEAGQE-FAGTGDLGFYHRGDLYVTGRLKD-MIIIAGRNYYSEDVEYAVIGSRP-EL 516
Query: 305 IYRGRIAVFSVRVLRDERICIVAEQRPDCGEEESFQWMSRVLQAVDSIHQVGIYCLALVQ 364
+ G A F+V +ER+ +VAE + + + + +A+ H + + LV
Sbjct: 517 VPNG-CAAFTVDAGDEERLVVVAEIERTHRKGDLDALLKGIREAIWLRHDISPGAVLLVS 575
Query: 365 PNFLPKTPLGGIHLSECKRRFLEGTL 390
P +PKT G + SEC++R +G L
Sbjct: 576 PGSVPKTSSGKVRRSECRKRLRDGEL 601
>UniRef50_Q7NJ79 Cluster: Gll1953 protein; n=1; Gloeobacter
violaceus|Rep: Gll1953 protein - Gloeobacter violaceus
Length = 584
Score = 133 bits (321), Expect = 3e-29
Identities = 112/463 (24%), Positives = 190/463 (41%), Gaps = 16/463 (3%)
Query: 444 DDSDAARKYQFISQILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLE 503
D+ A + + ++L+ RA + + FT L LT EL ++A I L
Sbjct: 6 DNPSIAAQPTTLVEMLQRRAIQQPERLAFTFLADGETQESNLTYGELDRRARAIAAHL-- 63
Query: 504 KGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSK 563
+ G+ L++P GLD + AFYGCLY G + PP P L +L + ++ ++
Sbjct: 64 QTFAAAGERAVLLYPTGLDYVAAFYGCLYAGVIAAPAYPPDPTQLEKSLAGLHGVIRDAQ 123
Query: 564 ATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKKLPIMYRAPTAE--MLAYLD 621
A VL+ V L+ S+ A + + L TD +P+ +R P E +A L
Sbjct: 124 ARWVLTTTGVHALVHSQLAGG--EERQPLQWLCTDPLPETPAE-SWRPPQVESASIALLQ 180
Query: 622 FSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYS 681
++ +T G+ ++HA V + ++ AC L + L + +Y
Sbjct: 181 YTSGSTAAPKGVMLTHANVLHNQKLIQSACHHTEQSTWVTWLPLHHNLALMSAVVQPVYV 240
Query: 682 GHHSILIPPSEVEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLA 741
G+ S+L+PP P WL A+S+Y+ R LC K + + ++L+
Sbjct: 241 GYLSVLMPPPAFLQRPLRWLRAISRYRGRGAAGPNFGFNLCIK----EIPPEQRGELDLS 296
Query: 742 CVRTCVVVAEERPRINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPSTV 801
++ E + +L FS F+ G P +G ++ + G S P
Sbjct: 297 SWEV-AIIGGEPIQCDLLERFSAAFAPCGFRPETFVPGYGLAESVLMVSVGRKSERPKVK 355
Query: 802 YVDLRALRNDRVSLVERGSPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQS 861
+D L R G ++ + + +PET+ +C +GEIWV
Sbjct: 356 ALDKAHLAAGRAVDAPPGQAEAIKVAGFELYDHDPTIAVVHPETRRRCQPGEIGEIWVAG 415
Query: 862 PHNASGYFTIYGDESDYADHFSAQLVTGNTGEVYARTGYLGFL 904
ASGY+ + D + A + + RTG LGF+
Sbjct: 416 GSVASGYW----QKPDISQATFAARIADCAEGPFLRTGDLGFI 454
Score = 79.8 bits (188), Expect = 4e-13
Identities = 91/394 (23%), Positives = 152/394 (38%), Gaps = 18/394 (4%)
Query: 1 MLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLASVLNGMHVIFIPYALMKVSPAS 60
+L + +++ AC++TE V L L AV+ V G + +P P
Sbjct: 199 VLHNQKLIQSACHHTEQSTWVTWLPLHHNLALMSAVVQPVYVGYLSVLMPPPAFLQRPLR 258
Query: 61 WMHMITKHRASIAIVKSRDLHWGL--LATRDHKEISLSSLRMLLVADGANPWSLSSCDQF 118
W+ I+++R A + + + + E+ LSS + ++ G P ++F
Sbjct: 259 WLRAISRYRGRGAAGPNFGFNLCIKEIPPEQRGELDLSSWEVAII--GGEPIQCDLLERF 316
Query: 119 LSVFQSKGVRGDAICPCACSSESMTVCIXXXXXXXXXXXXXVLSMSGLSYGVVRVDAENS 178
+ F G R + P +ES V + L + L+ G VDA
Sbjct: 317 SAAFAPCGFRPETFVPGYGLAES--VLMVSVGRKSERPKVKALDKAHLAAGRA-VDAPPG 373
Query: 179 LTSLTLQDCGQVMPSCVIVVVKMEGPAYLCKTDEVGEICVLSGATGSGYWGLPGLTNTVF 238
++ + V C+ E+GEI V G+ SGYW P ++ F
Sbjct: 374 QAEAIKVAGFELYDHDPTIAVVHPETRRRCQPGEIGEIWVAGGSVASGYWQKPDISQATF 433
Query: 239 RVRPLDSDGEPIGEEHYVRSXXXXXXXXXXXXXXXXSRDGLMTVTGRKHNMDDIIATVLA 298
R D E ++R+ ++ L+ ++GR H DI TV
Sbjct: 434 AARIAD-----CAEGPFLRTGDLGFIADGHFFLTGRCKE-LIIISGRNHYPQDIELTVQT 487
Query: 299 VEPMKFIYRGRIAVFSVRVLRDERICIVAEQRPD--CGEEESFQWMSRVLQAVDSIHQVG 356
P + A FS+ +ER+ + AE D + +S V +AV H +
Sbjct: 488 SHPA--LRPNSSAAFSIPSDGEERLVVAAELADDDPVPVPAAKSIVSAVQRAVAEQHGLR 545
Query: 357 IYCLALVQPNFLPKTPLGGIHLSECKRRFLEGTL 390
+ L++P LPKT +G I + R+L GTL
Sbjct: 546 -PTVVLLKPGTLPKTAIGKIQRLGARARYLAGTL 578
>UniRef50_A0PMY3 Cluster: Fatty-acid-CoA ligase; n=1; Mycobacterium
ulcerans Agy99|Rep: Fatty-acid-CoA ligase -
Mycobacterium ulcerans (strain Agy99)
Length = 575
Score = 133 bits (321), Expect = 3e-29
Identities = 122/456 (26%), Positives = 187/456 (41%), Gaps = 27/456 (5%)
Query: 459 LRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFP 518
L WRA++ D + L + T A L +A I L G N GD V L+
Sbjct: 15 LAWRARNQPDELAMVELRGMCGETDKATYARLDARARAIAFQLKSLG--NQGDRVLLVMG 72
Query: 519 PGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLR 578
LD + F C Y V V + P P+ ++ D L+ S +L
Sbjct: 73 HCLDYVVGFLACAYARRVAVNL--PVPRRAKHLDRLAHVVADCGAEVLLTSGPEAKELTA 130
Query: 579 SKEASNVLDSKA-----WPMTLDTDDMPKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGI 633
S A LD W + + +D P+ AP ++ + L ++ +T G+
Sbjct: 131 SVAADLRLDFLTVLRLDWLLAIPDEDWQ----PV---APASKDVCLLQYTSDSTSAPRGV 183
Query: 634 KMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIPPSEV 693
++H + C ++ L L Y +G L L+ I++G +L P
Sbjct: 184 VVTHDNLMFNCAQIQYGFGLTAEDRALSWLPLYHDMGLILGVLTPIFAGFPVVLADPLSF 243
Query: 694 EVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVVAEER 753
P LWL A+S Y++ T +LC +S L GI+L+C + AE
Sbjct: 244 VKRPDLWLRAISDYRITFTGGPNFAYDLCAD--AASYTDL--SGIDLSCWNVALNGAEP- 298
Query: 754 PRINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPSTVYVDLRALRNDRV 813
R F+ + LG +P + S+G N + EP+ V + + ALR +V
Sbjct: 299 IRATTLERFNAALAPLGWAPTCMQPSYGLAENTLAVSTKIPATEPTVVEIYVAALRQSQV 358
Query: 814 SLVERGSPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNASGYFTIYG 873
RG S L+ SG++L G V +PET G +GEIW+ A GY +G
Sbjct: 359 -CAPRGDSPSRRLVSSGRILAGTMVKIVDPETGHPVGPDRVGEIWLTGRSVAKGY---WG 414
Query: 874 DESDYADHFSAQLVTGNTGEVYARTGYLGFLRRTEI 909
+ + F+A+L G+ Y RTG LGF R E+
Sbjct: 415 RDIQTEEVFAARL-PGDPAR-YLRTGDLGFCRDDEL 448
Score = 58.4 bits (135), Expect = 1e-06
Identities = 85/394 (21%), Positives = 151/394 (38%), Gaps = 20/394 (5%)
Query: 1 MLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLASVLNGMHVIFI-PYALMKVSPA 59
++ +C + T + + L + GL VL + G V+ P + +K P
Sbjct: 190 LMFNCAQIQYGFGLTAEDRALSWLPLYHDMGLILGVLTPIFAGFPVVLADPLSFVK-RPD 248
Query: 60 SWMHMITKHRASIAIVKSRDLHWGLLA-TRDHKEISLSSLRMLLVA-DGANPWSLSSCDQ 117
W+ I+ +R I + + L A + ++S L VA +GA P ++ ++
Sbjct: 249 LWLRAISDYR--ITFTGGPNFAYDLCADAASYTDLSGIDLSCWNVALNGAEPIRATTLER 306
Query: 118 FLSVFQSKGVRGDAICPCACSSESMTVCIXXXXXXXXXXXXXVLSMSGLSYGVVRVDAEN 177
F + G + P +E+ T+ + + ++ L V +
Sbjct: 307 FNAALAPLGWAPTCMQPSYGLAEN-TLAVSTKIPATEPTVVEIY-VAALRQSQVCAPRGD 364
Query: 178 SLTSLTLQDCGQVMPSCVIVVVKMEGPAYLCKTDEVGEICVLSGATGSGYWGLPGLTNTV 237
S S L G+++ ++ +V E + D VGEI + + GYWG T V
Sbjct: 365 S-PSRRLVSSGRILAGTMVKIVDPE-TGHPVGPDRVGEIWLTGRSVAKGYWGRDIQTEEV 422
Query: 238 FRVRPLDSDGEPIGEEHYVRSXXXXXXXXXXXXXXXXSRDGLMTVTGRKHNMDDIIATVL 297
F R G+P Y+R+ +D L+ V G H D+ T
Sbjct: 423 FAAR---LPGDP---ARYLRTGDLGFCRDDELFVVGRLKD-LVIVHGANHYPQDLEETAE 475
Query: 298 AVEPMKFIYRGRIAVFSVRVLRDERICIVAEQRPDCGEE-ESFQWMSRVLQAVDSIHQVG 356
P + +AVF+ E + +VAE R + + R+ +A+ H+V
Sbjct: 476 GAHPA--VRSHFVAVFAEEREDREALIVVAEIRREAERGLDPRDVGQRIARAITREHEVS 533
Query: 357 IYCLALVQPNFLPKTPLGGIHLSECKRRFLEGTL 390
+ + L + +PKT G I S C+ +G L
Sbjct: 534 VDAVFLARCGEVPKTTSGKIQRSLCRELLRQGGL 567
>UniRef50_UPI000038D260 Cluster: COG1020: Non-ribosomal peptide
synthetase modules and related proteins; n=1; Nostoc
punctiforme PCC 73102|Rep: COG1020: Non-ribosomal
peptide synthetase modules and related proteins - Nostoc
punctiforme PCC 73102
Length = 1801
Score = 132 bits (320), Expect = 4e-29
Identities = 121/454 (26%), Positives = 194/454 (42%), Gaps = 20/454 (4%)
Query: 457 QILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVALI 516
+I+R+R+ S + F L + +T EL +KA+ I L + GD V L+
Sbjct: 18 EIIRFRSLSQAGKTAFLFLQDGETEAAKITYRELDQKAQAIAAQL--QTLTTPGDRVLLL 75
Query: 517 FPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKL 576
+P G + I AF GCLY G V V P +P + + ++ I ++ATLV+S SV+
Sbjct: 76 YPSGFEFIAAFVGCLYAGVVAV---PAYPPRRNQKMLRLQAIAIDAQATLVVSTTSVLGN 132
Query: 577 LRSK-EASNVLDSKAWPMTLDTDDMPKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKM 635
+ S+ E L K + TD++ + I YRA T + LA+L ++ +TG G+ +
Sbjct: 133 INSQAENPGFLGLKC----VATDNLIPIEDFIPYRA-TPDTLAFLQYTSGSTGTPKGVML 187
Query: 636 SHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIPPSEVEV 695
+H + R ++ A E L + +G L +Y G I + P+ +
Sbjct: 188 NHGNLLHNQRLIQTAFEHTEQTIFVGWLPLFHDMGLIGNTLQPLYLGIPCIFMSPTAFLM 247
Query: 696 NPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVVAEERPR 755
P WL A+S+YK + +LC S + + ++L+ + AE R
Sbjct: 248 RPLQWLMAISKYKATTSGGPNFAYDLCA----SKITSEERSTLDLSTWQVAFNGAEPI-R 302
Query: 756 INLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPSTVYVDLRALRNDRVSL 815
F+ F+ G A +G I G +P P AL V
Sbjct: 303 AETIERFASTFADCGFRREAFYPCYGMAETTLIVSGGLVAPPPVLQTFQKAALEQHLVVP 362
Query: 816 VERGSPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNASGYFTIYGDE 875
+ L+ G+ L ++V+ +PE +C +GEIWV S GY+ D
Sbjct: 363 ASNSDDATQTLVGCGQPLQDMRVVIVHPERMTRCNSDEIGEIWVSSASVTQGYWNQI-DS 421
Query: 876 SDYADHFSAQLVTGNTGEVYARTGYLGFLRRTEI 909
+ F A L G + RTG LGFL+ E+
Sbjct: 422 TQRT--FQAYLQDTGAGP-FLRTGDLGFLKDGEL 452
Score = 100 bits (240), Expect = 2e-19
Identities = 95/394 (24%), Positives = 164/394 (41%), Gaps = 18/394 (4%)
Query: 1 MLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLASVLNGMHVIFIPYALMKVSPAS 60
+L + R++ A +TE V L + GL L + G+ IF+ + P
Sbjct: 192 LLHNQRLIQTAFEHTEQTIFVGWLPLFHDMGLIGNTLQPLYLGIPCIFMSPTAFLMRPLQ 251
Query: 61 WMHMITKHRASIAIVKS--RDLHWGLLATRDHKEISLSSLRMLLVADGANPWSLSSCDQF 118
W+ I+K++A+ + + DL + + + + LS+ ++ +GA P + ++F
Sbjct: 252 WLMAISKYKATTSGGPNFAYDLCASKITSEERSTLDLSTWQVAF--NGAEPIRAETIERF 309
Query: 119 LSVFQSKGVRGDAICPCACSSESMTVCIXXXXXXXXXXXXXVLSMSGLSYGVVRVDAENS 178
S F G R +A PC +E T I + L +V + +
Sbjct: 310 ASTFADCGFRREAFYPCYGMAE--TTLIVSGGLVAPPPVLQTFQKAALEQHLVVPASNSD 367
Query: 179 LTSLTLQDCGQVMPSCVIVVVKMEGPAYLCKTDEVGEICVLSGATGSGYWGLPGLTNTVF 238
+ TL CGQ + +V+V E C +DE+GEI V S + GYW T F
Sbjct: 368 DATQTLVGCGQPLQDMRVVIVHPERMTR-CNSDEIGEIWVSSASVTQGYWNQIDSTQRTF 426
Query: 239 RVRPLDSDGEPIGEEHYVRSXXXXXXXXXXXXXXXXSRDGLMTVTGRKHNMDDIIATVLA 298
+ D+ P ++R+ +D L+ + GR + DI +T
Sbjct: 427 QAYLQDTGAGP-----FLRTGDLGFLKDGELFVTGRLKD-LIIIRGRNYYPQDIEST--- 477
Query: 299 VEPMKFIYRGRI-AVFSVRVLRDERICIVAE-QRPDCGEEESFQWMSRVLQAVDSIHQVG 356
V+ R A FSV + +ER+ ++ E +R E + + + AV H++
Sbjct: 478 VQKSHLSLRANCGAAFSVEIDGEERLVVIQEVERAYYRNLEVEEVVGAIRSAVSEEHELQ 537
Query: 357 IYCLALVQPNFLPKTPLGGIHLSECKRRFLEGTL 390
+Y + L++P + KT G + CK FL TL
Sbjct: 538 VYAVVLLKPGGILKTSSGKVQHYACKAGFLANTL 571
Score = 37.1 bits (82), Expect = 2.6
Identities = 16/38 (42%), Positives = 25/38 (65%), Gaps = 1/38 (2%)
Query: 952 VFVVGALDETIMLRGMRYHPIDIENSVMRCHKKI-AEC 988
+FV G L + I++RG Y+P DIE++V + H + A C
Sbjct: 452 LFVTGRLKDLIIIRGRNYYPQDIESTVQKSHLSLRANC 489
>UniRef50_Q7B6G6 Cluster: Peptide synthetase NRPS5-4-3; n=2;
Streptomyces|Rep: Peptide synthetase NRPS5-4-3 -
Streptomyces hygroscopicus
Length = 588
Score = 132 bits (320), Expect = 4e-29
Identities = 115/458 (25%), Positives = 201/458 (43%), Gaps = 20/458 (4%)
Query: 452 YQFISQILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGD 511
++ + L R + D + L ++ LT ELH+ A R +L G TG
Sbjct: 12 FRTLPDALWHRGERQPDRTAYVFLKDGEDATESLTYGELHEAACRRATMLSAAGL--TGR 69
Query: 512 HVALIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQ 571
+ L++P GL+ + GC+Y ++PP + + +R I D + + VL+
Sbjct: 70 NAVLMYPSGLEFVRTLLGCMYGRVAGAPVQPPRRR---AEVERLRRIADDAGTSTVLTTT 126
Query: 572 SVIKLLRSKEAS-NVLDSKAWPMTLDTDDMPKKKLPIMYRAPTAEMLAYLDFSVSTTGML 630
VI+ LR + A LD T D + + R P + +A L ++ +TG
Sbjct: 127 DVIRDLRERFADLPALDGLDLVATDDPGALHTGEPSTPERLPDPQDIALLQYTSGSTGHP 186
Query: 631 AGIKMSHAA-VTSLCRSMKI-ACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILI 688
G+ +SHA + ++ + ++ CE P + L + +G + +++G S L+
Sbjct: 187 KGVMVSHANFLANVVETDELWPCE--PRGTVVNWLPLFHDMGMLFGVVLPLWAGIPSYLM 244
Query: 689 PPSEVEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGI-NLACVRTCV 747
P PA WL A+S++ + ELC + S + + G+ +L+ R V
Sbjct: 245 APESFIRRPARWLEALSRFGGTHSAAPSFAYELCVRAAESGM----TAGVGDLSSWRVAV 300
Query: 748 VVAEERPRINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPSTVYVDLRA 807
AE R ++ +F+ F+ G P A+ ++G N + EP +++ A
Sbjct: 301 NGAEP-VRWSVVRAFTDTFAPHGFDPMAMCPAYGLAENTLKATGTRADREPMVLWLSAEA 359
Query: 808 LRNDRVSLVERGSPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNASG 867
LR R V + ++ + SG+ + G V +P T+ C H+GEIW+ P A G
Sbjct: 360 LREGRAQPVGERTDSAVPAVGSGRDVAGTHVRIVDPVTRQPCTPGHVGEIWISGPCVADG 419
Query: 868 YFTIYGDESDYADHFSAQLVTG-NTGEVYARTGYLGFL 904
Y +G + D F A++ + + RTG LGFL
Sbjct: 420 Y---WGRPAASEDTFRARVADDPDDAAPHLRTGDLGFL 454
Score = 46.4 bits (105), Expect = 0.004
Identities = 69/335 (20%), Positives = 117/335 (34%), Gaps = 11/335 (3%)
Query: 58 PASWMHMITKHRASIAIVKSRDLHWGLLATRDHKEISLSSLRMLLVA-DGANPWSLSSCD 116
PA W+ +++ + + S + A + L VA +GA P S
Sbjct: 253 PARWLEALSRFGGTHSAAPSFAYELCVRAAESGMTAGVGDLSSWRVAVNGAEPVRWSVVR 312
Query: 117 QFLSVFQSKGVRGDAICPCACSSESMTVCIXXXXXXXXXXXXXVLSMSGLSYGVVRVDAE 176
F F G A+CP +E+ LS L G + E
Sbjct: 313 AFTDTFAPHGFDPMAMCPAYGLAENTLKATGTRADREPMVLW--LSAEALREGRAQPVGE 370
Query: 177 NSLTSLTLQDCGQVMPSCVIVVVKMEGPAYLCKTDEVGEICVLSGATGSGYWGLPGLTNT 236
+ +++ G+ + + +V C VGEI + GYWG P +
Sbjct: 371 RTDSAVPAVGSGRDVAGTHVRIVDPV-TRQPCTPGHVGEIWISGPCVADGYWGRPAASED 429
Query: 237 VFRVRPLDSDGEPIGEEHYVRSXXXXXXXXXXXXXXXXSRDGLMTVTGRKHNMDDIIATV 296
FR R D +P ++R+ +D ++ GR H DI +
Sbjct: 430 TFRARVAD---DPDDAAPHLRTGDLGFLYDGDLYVTGRMKDVIIR-RGRNHYPQDI--EL 483
Query: 297 LAVEPMKFIYRGRIAVFSVRVLRDERICIVAEQRPDCGEEESFQWM-SRVLQAVDSIHQV 355
A + + A FS+ ER+ +V E + RV +AV + ++
Sbjct: 484 SAERAVPGLQPNCAAAFSLDDGERERLVVVVEAGGRVLAALGADGLRERVREAVRAEQRI 543
Query: 356 GIYCLALVQPNFLPKTPLGGIHLSECKRRFLEGTL 390
+ +V+ LPKT G + C+ + +G L
Sbjct: 544 TPDDIVVVRRGKLPKTSSGKVQRRACRSLYQDGEL 578
>UniRef50_Q0B1F1 Cluster: Beta-ketoacyl synthase; n=1; Burkholderia
ambifaria AMMD|Rep: Beta-ketoacyl synthase -
Burkholderia cepacia (strain ATCC 53795 / AMMD)
Length = 1474
Score = 132 bits (320), Expect = 4e-29
Identities = 126/461 (27%), Positives = 206/461 (44%), Gaps = 32/461 (6%)
Query: 451 KYQFISQILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTG 510
K++ +++I +R + + F L + LT +L K+A I L +G G
Sbjct: 6 KFRTVTEIFIFRGKVEPEKRAFIFLENGESERARLTFGDLDKRARGIAARL--QGMAQPG 63
Query: 511 DHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSN 570
D V L++PPGL+ ICA+ GCLY G + V P +P H ++ IV + + L++
Sbjct: 64 DRVLLVYPPGLEFICAWVGCLYAGLIGV---PAYPPRRHRPADRLKAIVADASPVVALTD 120
Query: 571 QSVIKLL--RSKEASNVLDSKAWPMTLDTDDMPKKKLPIMYRAP--TAEMLAYLDFSVST 626
+ + + R+ S+ L+ K T D P ++ +RAP T + LA L ++ +
Sbjct: 121 AATLDGIAHRADGYSDTLELKIL-ATDQGFDAPAEQ----WRAPDITPQTLALLQYTSGS 175
Query: 627 TGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSI 686
TG G+ +SHA + S + A + S L + +GF L IY G ++
Sbjct: 176 TGTPKGVMISHANILSNMAVIAEASDADASTVFVSWLPVFHDMGFFGKVLLPIYLGVPAV 235
Query: 687 LIPPSEVEVNPALWLSAVSQYKVRDTFCSYG--VMELCTKGLGSSVNQLKSKGINLACVR 744
L+ P+ P WL A+++Y R T C+ +LC + + L ++L+ R
Sbjct: 236 LMAPAAFVQKPIRWLQAITKY--RGTHCAAPDFAYDLCARKISDEARAL----LDLSSWR 289
Query: 745 TCVVVAEERPRINLTNSFSKLFSALGLSPRAVSTSFG-CRVNIAICLQGASSPEPSTVYV 803
AE R FS+ F+A G + +G + I Q A S P
Sbjct: 290 VAFNGAEP-VRAESVARFSRAFAACGFHAHTMRPVYGMAEATLFISGQPARS-LPLVADY 347
Query: 804 DLRALRNDRVSLVERGSPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPH 863
D L + + G H+ L+ G+ ++ NP+T +C +GEIWV P
Sbjct: 348 DADGLARGVATRSDGGKRHA--LVSCGRAWAEHRLQIVNPDTGERCPPDRIGEIWVTGPS 405
Query: 864 NASGYFTIYGDESDYADHFSAQLVTGNTGEVYARTGYLGFL 904
GY+ DE+++ F A+L G+ Y RTG LGF+
Sbjct: 406 VGVGYWNRV-DETEHT--FRAKL-DGDDAH-YLRTGDLGFV 441
Score = 74.1 bits (174), Expect = 2e-11
Identities = 89/392 (22%), Positives = 150/392 (38%), Gaps = 23/392 (5%)
Query: 1 MLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLASVLNGMHVIFIPYALMKVSPAS 60
+L++ +++ A + V L + G + VL + G+ + + A P
Sbjct: 189 ILSNMAVIAEASDADASTVFVSWLPVFHDMGFFGKVLLPIYLGVPAVLMAPAAFVQKPIR 248
Query: 61 WMHMITKHRASIAIVKSRDLHWGLLATRDHKE----ISLSSLRMLLVADGANPWSLSSCD 116
W+ ITK+R + D + L A + E + LSS R+ +GA P S
Sbjct: 249 WLQAITKYRGTHCAAP--DFAYDLCARKISDEARALLDLSSWRVAF--NGAEPVRAESVA 304
Query: 117 QFLSVFQSKGVRGDAICPCACSSESMTVCIXXXXXXXXXXXXXVLSMSGLSYGVVRVDAE 176
+F F + G + P +E+ T+ I GL+ GV
Sbjct: 305 RFSRAFAACGFHAHTMRPVYGMAEA-TLFISGQPARSLPLVADY-DADGLARGVATRSDG 362
Query: 177 NSLTSLTLQDCGQVMPSCVIVVVKMEGPAYLCKTDEVGEICVLSGATGSGYWGLPGLTNT 236
+L CG+ + +V + C D +GEI V + G GYW T
Sbjct: 363 GKRHALV--SCGRAWAEHRLQIVNPD-TGERCPPDRIGEIWVTGPSVGVGYWNRVDETEH 419
Query: 237 VFRVRPLDSDGEPIGEEHYVRSXXXXXXXXXXXXXXXXSRDGLMTVTGRKHNMDDIIATV 296
FR + LD D + HY+R+ +D L+ V GR H D+ +
Sbjct: 420 TFRAK-LDGD-----DAHYLRTGDLGFVDGENLFVTGRLKD-LIIVAGRNHYPQDLEQSA 472
Query: 297 LAVEPMKFIYRGRIAVFSVRVLRDERICIVAEQRPDC-GEEESFQWMSRVLQAVDSIHQV 355
P + A FS+ V ER+ I E R + ++ + + + + H V
Sbjct: 473 EGSHPA--LAPNASAAFSINVDDVERVVIACEVRREALNTLDAEAVAAEIRRKLAEAHDV 530
Query: 356 GIYCLALVQPNFLPKTPLGGIHLSECKRRFLE 387
+Y L++P + +T G I S ++ FL+
Sbjct: 531 DLYAAILLKPATILRTSSGKIQRSRIRQAFLD 562
>UniRef50_Q4KK26 Cluster: Pyoverdine synthetase; n=1; Pseudomonas
fluorescens Pf-5|Rep: Pyoverdine synthetase -
Pseudomonas fluorescens (strain Pf-5 / ATCC BAA-477)
Length = 620
Score = 132 bits (319), Expect = 5e-29
Identities = 121/461 (26%), Positives = 209/461 (45%), Gaps = 28/461 (6%)
Query: 455 ISQILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLL-LEKGRVNTGDHV 513
++++L +RA D + F L ++ AEL K+++R+ L + + R V
Sbjct: 40 VTEVLAYRAWRQPDAIAFIHLLDGEREEASISYAELWKRSQRLAAALQIFEPREK---RV 96
Query: 514 ALIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSV 573
++F G+D I + +G L GAV + PP L + +I + LVL++
Sbjct: 97 LMLFETGIDYIVSLFGLLLAGAVAIPAFPPVGTR---GLERLALICADAHPQLVLTSS-- 151
Query: 574 IKLLRSKEASNVL--DSKAWPMTLDTDDMPKKKLPIMYRAPTAEMLAYLDFSVSTTGMLA 631
+ +RS+E N L P +D + + + +A LA L ++ +T
Sbjct: 152 -RFMRSQERVNALLQGDLPVPQWVDPEQLAEADSSWRGQALAHGQLALLQYTSGSTSAPK 210
Query: 632 GIKMSHAAVTSLCRSMKIACELYPSRHIALC--LDPYCGLGFALWCLSSIYSGHHSILIP 689
G+ ++H + S CRS + + P+R+ C L PY +G L I+ ++LI
Sbjct: 211 GVMLTHDNLYSNCRSA--SQWMGPARNRVGCSWLPPYHDMGLMGGILQPIFDAFPTVLIS 268
Query: 690 PSEVEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVV 749
P P WL AVS+Y T +LC + ++ + ++L+ ++
Sbjct: 269 PGHFVQRPLRWLDAVSRYGADVTIAPNFAFDLCVE----NITDEELAELDLSKLKAIYCG 324
Query: 750 AEERPRINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPS-TVYVDLRAL 808
AE + L FS+ F+A G +P A+ +G + + G EP+ VD L
Sbjct: 325 AEPVRQSTLAR-FSERFAAAGFNPAALGPCYGL-AEATVLVSGKRHDEPAFNTQVDRDQL 382
Query: 809 RNDRVSLVERGSPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNASGY 868
+ +++V+ +L L+ SG++ PG++V +P + D +GEIWVQ + +GY
Sbjct: 383 ASGTLAIVDAEDARALPLVSSGRVAPGLRVAIVDPVSLQPVADGQIGEIWVQGDNVGAGY 442
Query: 869 FTIYGDESDYADHFSAQLVTGNTGEVYARTGYLGFLRRTEI 909
+G E+ F A L G G + RTG LG L R E+
Sbjct: 443 ---WGKEALSQQVFRASL-PGIHGR-FMRTGDLGALHRDEL 478
Score = 61.7 bits (143), Expect = 1e-07
Identities = 81/353 (22%), Positives = 140/353 (39%), Gaps = 22/353 (6%)
Query: 29 ETGLWHAVLASVLNGMHVIFIPYALMKVSPASWMHMITKHRASIAIVKSR--DLHWGLLA 86
+ GL +L + + + I P W+ ++++ A + I + DL +
Sbjct: 247 DMGLMGGILQPIFDAFPTVLISPGHFVQRPLRWLDAVSRYGADVTIAPNFAFDLCVENIT 306
Query: 87 TRDHKEISLSSLRMLLVADGANPWSLSSCDQFLSVFQSKGVRGDAICPCACSSESMTVCI 146
+ E+ LS L+ + GA P S+ +F F + G A+ PC +E+ TV +
Sbjct: 307 DEELAELDLSKLKAIYC--GAEPVRQSTLARFSERFAAAGFNPAALGPCYGLAEA-TVLV 363
Query: 147 XXXXXXXXXXXXXVLSMSGLSYGVVRVDAENSLTSLTLQDCGQVMPSCVIVVVKMEGPAY 206
V S + VDAE++ +L L G+V P + +V
Sbjct: 364 SGKRHDEPAFNTQVDRDQLASGTLAIVDAEDA-RALPLVSSGRVAPGLRVAIVDPVSLQP 422
Query: 207 LCKTDEVGEICVLSGATGSGYWGLPGLTNTVFRVRPLDSDGEPIGEEHYVRSXXXXXXXX 266
+ ++GEI V G+GYWG L+ VFR G ++R+
Sbjct: 423 VAD-GQIGEIWVQGDNVGAGYWGKEALSQQVFRASLPGIHG------RFMRTGDLGALHR 475
Query: 267 XXXXXXXXSRDGLMTVTGRKHNMDDIIATVLAVEPMKFIYRGRIAVFSVRVLRDERICIV 326
+D L+ + GR D+ V + +P + G +AV + + E++ IV
Sbjct: 476 DELFVTGRLKD-LIIIAGRNLYPQDLELAVESADP-RIRSNGCVAV-GIDNGQQEQLAIV 532
Query: 327 AEQRPDCGEEESFQWMSRVLQAVDSIHQVGIYCLALVQPNFLPKTPLGGIHLS 379
AE + +E+ Q R + + Q G V P + P+GGI L+
Sbjct: 533 AEVKRSEKLDEAQQEQLRQVITSALVSQFG------VAPARIHLAPMGGIPLT 579
>UniRef50_Q21HW6 Cluster: AMP-dependent synthetase and ligase; n=1;
Saccharophagus degradans 2-40|Rep: AMP-dependent
synthetase and ligase - Saccharophagus degradans (strain
2-40 / ATCC 43961 / DSM 17024)
Length = 588
Score = 132 bits (319), Expect = 5e-29
Identities = 103/459 (22%), Positives = 198/459 (43%), Gaps = 16/459 (3%)
Query: 451 KYQFISQILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTG 510
+++ + +L+WRAQ + V FT L + +T EL ++A +I L ++ N
Sbjct: 7 EFETLVDLLQWRAQKMPNKVAFTFLKDGVDETDQITFRELDERARQIAARLQQENTPNPT 66
Query: 511 DHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSN 570
L++P G++ +CA +GC+Y G V + P ++ + +++ D ++
Sbjct: 67 --ALLLYPQGIEHMCALWGCMYAGVRAVPLFVPQNDRVYKRVKSIQQ--DSGAQYVLCDR 122
Query: 571 QSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKKLPIMYRAPTAEMLAYLDFSVSTTGML 630
+S +L + + + S W ++ + + ++ A + +AY ++ +TG
Sbjct: 123 ESYDRLEKRFDRMPEVASLQWLISDELEASLANDWKLV--AQERDTVAYYQYTSGSTGTP 180
Query: 631 AGIKMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIPP 690
G+ +SH V + + + + L + +G + +Y+G H++L P
Sbjct: 181 KGVMVSHGNVIYNVSDIDASWDHSEDTVLVSWLPIFHDMGLIYGFMQGVYNGFHTVLFSP 240
Query: 691 SEVEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVVA 750
+ P WL A+S Y+ + +C + V + K ++L+ +R +
Sbjct: 241 NAFAQRPYTWLKAISDYRATHSGGPNSAYIMCVE----KVLDEQKKDLDLSSLRV-MFNG 295
Query: 751 EERPRINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPSTVYVDLRALRN 810
E R + SF++ F+ G + +G P+ + VD +AL +
Sbjct: 296 SEPVRESTLQSFTQAFAECGFKAEMHTPCYGLAEATLKVTATKLGEYPNHLTVDAKALAS 355
Query: 811 DRVSLVERGSPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNASGYFT 870
++V + G + + SG + +V NP + C +GEIWV+ P NA GY
Sbjct: 356 NKVLPLLAGEEGQV-FVSSGVTVQQTEVKIVNPVSSEVCAPDSIGEIWVKGPTNAMGY-- 412
Query: 871 IYGDESDYADHFSAQLVTGNTGEVYARTGYLGFLRRTEI 909
Y E D + F+A + G Y RTG LGF E+
Sbjct: 413 -YRKEEDTREIFNAYINETVDGP-YMRTGDLGFFYNNEL 449
Score = 69.3 bits (162), Expect = 5e-10
Identities = 91/393 (23%), Positives = 162/393 (41%), Gaps = 31/393 (7%)
Query: 8 LSVACNYTEGEHMVCVLDFKRETGLWHAVLASVLNGMH-VIFIPYALMKVSPASWMHMIT 66
+ + +++E +V L + GL + + V NG H V+F P A + P +W+ I+
Sbjct: 197 IDASWDHSEDTVLVSWLPIFHDMGLIYGFMQGVYNGFHTVLFSPNAFAQ-RPYTWLKAIS 255
Query: 67 KHRASIAIVKSRDLHWGLLATRDH--KEISLSSLRMLLVADGANPWSLSSCDQFLSVFQS 124
+RA+ + + + D K++ LSSLR++ +G+ P S+ F F
Sbjct: 256 DYRATHSGGPNSAYIMCVEKVLDEQKKDLDLSSLRVMF--NGSEPVRESTLQSFTQAFAE 313
Query: 125 KGVRGDAICPCACSSESMTVCIXXXXXXXXXXXXXVLSMSGLSYGVVRVDAENSLTSLTL 184
G + + PC +E+ T+ + V + + A N + L
Sbjct: 314 CGFKAEMHTPCYGLAEA-TLKVTATKLGEYPNHLTVDA---------KALASNKVLPLLA 363
Query: 185 QDCGQVMPSCVIVV----VKMEGP--AYLCKTDEVGEICVLSGATGSGYWGLPGLTNTVF 238
+ GQV S + V VK+ P + +C D +GEI V GY+ T +F
Sbjct: 364 GEEGQVFVSSGVTVQQTEVKIVNPVSSEVCAPDSIGEIWVKGPTNAMGYYRKEEDTREIF 423
Query: 239 RVRPLDSDGEPIGEEHYVRSXXXXXXXXXXXXXXXXSRDGLMTVTGRKHNMDDIIATVLA 298
++ P Y+R+ +D L+ V GR DI V
Sbjct: 424 NAYINETVDGP-----YMRTGDLGFFYNNELYIAGRLKD-LIIVRGRNCYPQDIEEIVEN 477
Query: 299 VEPMKFIYRGRIAVFSVRVLRDERICIVAE-QRPDCGEEESFQWMSRVLQAVDSIHQVGI 357
P G A FS+ V DER+ +V +R ++ + + + ++V + + V +
Sbjct: 478 CHPALSPSAG--AAFSLDVDGDERLIVVQSVRRSHLKHIDAPEIFNAIRRSVSAQYGVKV 535
Query: 358 YCLALVQPNFLPKTPLGGIHLSECKRRFLEGTL 390
+ + L+ P +P+T G I CK+ + + TL
Sbjct: 536 HDIQLLMPASIPRTTSGKIQRRACKQAYQQKTL 568
>UniRef50_A6GHN6 Cluster: Non-ribosomal peptide synthase; n=1;
Plesiocystis pacifica SIR-1|Rep: Non-ribosomal peptide
synthase - Plesiocystis pacifica SIR-1
Length = 1424
Score = 132 bits (319), Expect = 5e-29
Identities = 116/462 (25%), Positives = 197/462 (42%), Gaps = 22/462 (4%)
Query: 458 ILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEK--GRVNTGDHVAL 515
+ RW ++ L + +G S L+ +L A I + +LE+ + + G L
Sbjct: 20 VTRWASEMPESLAFRHLADGRGDDSSSLSYGQLDANARVIASAMLEQLGPQADEGARALL 79
Query: 516 IFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIK 575
I+ PGL+ I AF CLY G V + PP P L TTLP + I ++ +LVL+ + +
Sbjct: 80 IYAPGLEFIEAFVACLYAGVTAVPVYPPSPAQLETTLPRLLAIATDAEPSLVLTTKMISG 139
Query: 576 LLRS-KEASNVLDSKAWPMTLDTDDMPKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIK 634
LL+ + + S W T + L + RA A + A L ++ +TG G+
Sbjct: 140 LLQPFTQPAPAFASARWLATDGAVEAGGAAL-VGLRA-RASLPALLQYTSGSTGTPKGVV 197
Query: 635 MSHA-------AVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSIL 687
++HA A+ S ++ L Y +G L ++Y G +
Sbjct: 198 VTHANLIANERAIASAFGTLDAIARGSKIESGVSWLPTYHDMGLMGKVLQTLYLGVWTTT 257
Query: 688 IPPSEVEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCV 747
+ P P WL A+S+Y+ + ELC + + + +G++L+ R
Sbjct: 258 MSPLTFIKQPVRWLEAISRYRATISGGPNFAFELCVR----RIRDEEMEGLDLSSWRVAF 313
Query: 748 VVAEERPRINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPSTVYVDLRA 807
AE R F++ F+ G A+ +G N I T+ + A
Sbjct: 314 CGAEP-IRPETLERFAERFAPWGFDRAALFPCYGLAENTLIVSGAWLGQGADTLDLRAEA 372
Query: 808 LRNDRVSLVERGSPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNASG 867
+ DR L G+ S ++ G ++P +V +PET+ +GE+WV P A+G
Sbjct: 373 IERDRAELAAPGTLGSAQVVSCGGVVPDHEVRVVDPETREAAEPGGIGELWVGGPSVAAG 432
Query: 868 YFTIYGDESDYADHFSAQLVTGNTGEVYARTGYLGFLRRTEI 909
Y + A+ F+A+L +G + RTG LGF+ ++
Sbjct: 433 Y---WRKPELSAETFAAELASGE--GPFLRTGDLGFVHHGQV 469
Score = 62.9 bits (146), Expect = 4e-08
Identities = 88/367 (23%), Positives = 143/367 (38%), Gaps = 23/367 (6%)
Query: 29 ETGLWHAVLASVLNGMHVIFI-PYALMKVSPASWMHMITKHRASIAIVKSRDLHWGLLAT 87
+ GL VL ++ G+ + P +K P W+ I+++RA+I+ + +
Sbjct: 238 DMGLMGKVLQTLYLGVWTTTMSPLTFIK-QPVRWLEAISRYRATISGGPNFAFELCVRRI 296
Query: 88 RDHKE--ISLSSLRMLLVADGANPWSLSSCDQFLSVFQSKGVRGDAICPCACSSESMTVC 145
RD + + LSS R+ GA P + ++F F G A+ PC +E+
Sbjct: 297 RDEEMEGLDLSSWRVAFC--GAEPIRPETLERFAERFAPWGFDRAALFPCYGLAEN--TL 352
Query: 146 IXXXXXXXXXXXXXVLSMSGLSYGVVRVDAENSLTSLTLQDCGQVMPSCVIVVVKMEGPA 205
I L + + A +L S + CG V+P + VV E
Sbjct: 353 IVSGAWLGQGADTLDLRAEAIERDRAELAAPGTLGSAQVVSCGGVVPDHEVRVVDPE-TR 411
Query: 206 YLCKTDEVGEICVLSGATGSGYWGLPGLTNTVFRVRPLDSDGEPIGEEHYVRSXXXXXXX 265
+ +GE+ V + +GYW P L+ F L S GE ++R+
Sbjct: 412 EAAEPGGIGELWVGGPSVAAGYWRKPELSAETFAAE-LAS-----GEGPFLRTGDLGFVH 465
Query: 266 XXXXXXXXXSRDGLMTVTGRKHNMDDIIATVLAVEPMKFIYRGRIAVFSVRVLRDERICI 325
++ L+ V GR DI A+V I G + + V E+ +
Sbjct: 466 HGQVYVTGRRKE-LIVVRGRNIYPQDIEASVATCHAA--IRPGGVVAVGLEVDGHEQAGL 522
Query: 326 VAEQRP---DCGEEESFQWMSRVLQAVDSIHQVGIYCLALVQPNFLPKTPLGGIHLSECK 382
V E R D E + R+ A + H + + LALV P +PKT G + + +
Sbjct: 523 VVEVRKRKLDAATREQLEQAIRL--AASTEHGLNLARLALVPPRTVPKTSSGKLQRTLVR 580
Query: 383 RRFLEGT 389
R L GT
Sbjct: 581 DRLLAGT 587
Score = 37.9 bits (84), Expect = 1.5
Identities = 22/59 (37%), Positives = 31/59 (52%), Gaps = 6/59 (10%)
Query: 949 HDAVFVVGALDETIMLRGMRYHPIDIENSVMRCHKKIAECAVFTWTNLLVVVVELDGND 1007
H V+V G E I++RG +P DIE SV CH I V + V +E+DG++
Sbjct: 466 HGQVYVTGRRKELIVVRGRNIYPQDIEASVATCHAAIRPGGV------VAVGLEVDGHE 518
>UniRef50_Q1D3K4 Cluster: Non-ribosomal peptide synthase; n=2;
Myxococcus xanthus DK 1622|Rep: Non-ribosomal peptide
synthase - Myxococcus xanthus (strain DK 1622)
Length = 3292
Score = 129 bits (312), Expect = 3e-28
Identities = 117/457 (25%), Positives = 197/457 (43%), Gaps = 24/457 (5%)
Query: 457 QILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVALI 516
++LR RAQ D ++T L T A L ++A I L E + G + L+
Sbjct: 16 ELLRERAQQAPDFGLYTFLVDGETQEDRQTYAALDRRARAIAARLAE---LPPGTRILLL 72
Query: 517 FPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKL 576
+ PG++ I AF+GCLY G V V + PP +L ++ I ++AT L ++L
Sbjct: 73 YVPGVEYIAAFFGCLYAGMVAVPVYPPRHDR---SLLRLQAIATDAQATAGLIRSEHLEL 129
Query: 577 LRS-KEASNVLDSKAWPMTLDTDDMPKKKLPIMYRAP--TAEMLAYLDFSVSTTGMLAGI 633
LR + L W +T + DD + + P + + LA+L ++ +T + G+
Sbjct: 130 LRQFYPIAPELAQLRWIVTDEVDD----RASDAWTPPPLSGDSLAFLQYTSGSTSLPKGV 185
Query: 634 KMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIPPSEV 693
++H + +++ + + L PY +G L +Y+G+ ++L+ P +
Sbjct: 186 TLTHRNLLHNLEAIRRCFRQDQTSRAIIWLPPYHDMGLIGGILQPLYTGYPAVLMSPMDF 245
Query: 694 EVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVVAEER 753
P WL A+S+Y+ + LC + + + +G++L+ R AE
Sbjct: 246 LQQPLRWLQAISRYRGTTSGGPDFAYTLCAR----KIRPEQREGLDLSSWRVAFNGAEP- 300
Query: 754 PRINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPSTVYVDLRALRNDRV 813
R + F+ F +G +G I P D +AL+ +
Sbjct: 301 IRPETLDRFTHAFGPVGFRREMFYPCYGLAEATLIVSGSEVGQAPHVASFDGQALQRGQA 360
Query: 814 SLVERGSPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNASGYFTIYG 873
VE G + L+ SG+ + ++ +PET D +GEIWV A GY +G
Sbjct: 361 IPVEAGHAAAHPLVGSGRNVIDGRLAVVDPETFELRRDGEIGEIWVSGSSVAGGY---WG 417
Query: 874 DESDYADHFSAQLVTGNTGE-VYARTGYLGFLRRTEI 909
F A+L TGE + RTG LGFLR E+
Sbjct: 418 QPEATTRTFQARL--RGTGEGPFLRTGDLGFLRDGEL 452
Score = 77.0 bits (181), Expect = 3e-12
Identities = 89/369 (24%), Positives = 145/369 (39%), Gaps = 25/369 (6%)
Query: 29 ETGLWHAVLASVLNGMHVIFIPYALMKVSPASWMHMITKHRASIAIVKSRDLHWGLLATR 88
+ GL +L + G + + P W+ I+++R + + D + L A +
Sbjct: 220 DMGLIGGILQPLYTGYPAVLMSPMDFLQQPLRWLQAISRYRGTTS--GGPDFAYTLCARK 277
Query: 89 DHKE----ISLSSLRMLLVADGANPWSLSSCDQFLSVFQSKGVRGDAICPCACSSESMTV 144
E + LSS R+ +GA P + D+F F G R + PC +E+ +
Sbjct: 278 IRPEQREGLDLSSWRVAF--NGAEPIRPETLDRFTHAFGPVGFRREMFYPCYGLAEATLI 335
Query: 145 CIXXXXXXXXXXXXXVLSMSG--LSYG-VVRVDAENSLTSLTLQDCGQVMPSCVIVVVKM 201
V S G L G + V+A ++ L G+ + + VV
Sbjct: 336 V----SGSEVGQAPHVASFDGQALQRGQAIPVEAGHAAAH-PLVGSGRNVIDGRLAVVDP 390
Query: 202 EGPAYLCKTDEVGEICVLSGATGSGYWGLPGLTNTVFRVRPLDSDGEPIGEEHYVRSXXX 261
E L + E+GEI V + GYWG P T F+ R + GE ++R+
Sbjct: 391 E-TFELRRDGEIGEIWVSGSSVAGGYWGQPEATTRTFQARLRGT-----GEGPFLRTGDL 444
Query: 262 XXXXXXXXXXXXXSRDGLMTVTGRKHNMDDIIATVLAVEPMKFIYRGRIAVFSVRVLRDE 321
++D L+ + G H DI TV P + G A FSV E
Sbjct: 445 GFLRDGELFVTGRAKD-LIIIRGLNHFPQDIEFTVEKCHPA--VRPGSGAAFSVEADGTE 501
Query: 322 RICIVAEQRPDCGEEESFQWMSRVLQAVDSIHQVGIYCLALVQPNFLPKTPLGGIHLSEC 381
++ +V E E + +S + + V H++ + L++P +PKT G I C
Sbjct: 502 QLVVVYEANAQRAESGLDEVISAIRRTVAEQHELMASSVVLIEPGSVPKTSSGKIQRHAC 561
Query: 382 KRRFLEGTL 390
+ FL G L
Sbjct: 562 RAAFLAGEL 570
Score = 39.9 bits (89), Expect = 0.36
Identities = 39/159 (24%), Positives = 66/159 (41%), Gaps = 13/159 (8%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPH 544
LT EL +++ ++ + L +G V V L + + G L G + + P H
Sbjct: 2240 LTYGELARRSNQLAHHLRRRG-VGPDTRVGLYVRRSFERVIGMLGILKAGGAYLPLEPGH 2298
Query: 545 PQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKK 604
P+ T RM+ D A LVL+ +++ L A + W + +
Sbjct: 2299 PRERLT-----RMLTDAD-ARLVLTEEALEPTLEGILADRLCLDAGW------SSIAGES 2346
Query: 605 LPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSL 643
+ A AE LAY+ ++ +TG G+ + H AV L
Sbjct: 2347 AGGVPDAAGAENLAYVMYTSGSTGQPKGVCIPHRAVVRL 2385
Score = 35.9 bits (79), Expect = 5.9
Identities = 22/65 (33%), Positives = 35/65 (53%), Gaps = 6/65 (9%)
Query: 952 VFVVGALDETIMLRGMRYHPIDIENSVMRCHKKI--AECAVFT----WTNLLVVVVELDG 1005
+FV G + I++RG+ + P DIE +V +CH + A F+ T LVVV E +
Sbjct: 452 LFVTGRAKDLIIIRGLNHFPQDIEFTVEKCHPAVRPGSGAAFSVEADGTEQLVVVYEANA 511
Query: 1006 NDSEA 1010
+E+
Sbjct: 512 QRAES 516
>UniRef50_Q08U40 Cluster: Beta-ketoacyl synthase; n=1; Stigmatella
aurantiaca DW4/3-1|Rep: Beta-ketoacyl synthase -
Stigmatella aurantiaca DW4/3-1
Length = 584
Score = 129 bits (312), Expect = 3e-28
Identities = 114/459 (24%), Positives = 188/459 (40%), Gaps = 17/459 (3%)
Query: 451 KYQFISQILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTG 510
K + I +L +RA + + F L L+ ELH + + L ++G G
Sbjct: 18 KSRTILDVLGYRAAAHGNRTAFIFLEEGEVEEGKLSFQELHANHLVVAHALRKEGLA--G 75
Query: 511 DHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSN 570
V L + PGLD + AF+GCL G VP+ + PP P ++ IVD + A VL+
Sbjct: 76 KRVLLFYLPGLDFVIAFFGCLAAGVVPIAVPPPLPTE---RTSRIQAIVDDAHAAAVLTA 132
Query: 571 QSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKKLPIMYRAPTAEMLAYLDFSVSTTGML 630
++ +L+S A + + + TD + + P P + LA+L ++ +T +
Sbjct: 133 GDLVPVLQSWLAQS--ERLGGLPLIATDAVDALESPAGAHRPAPDDLAFLQYTSGSTTLP 190
Query: 631 AGIKMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIPP 690
G+ + H + + ++ + L + +G L +Y+G S+++ P
Sbjct: 191 RGVMVGHDNLLANLECIQRPLLIGADSVSVTWLPCFHDMGLINGVLEPVYAGCLSVMMSP 250
Query: 691 SEVEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVVA 750
P WL A+S+Y+ + +LC + + Q G+ L R + A
Sbjct: 251 LAFIRRPRRWLEAISRYQATHSGGPNFAYDLCVRKIPPRDRQ----GLELGSWRQAYLSA 306
Query: 751 EERPRINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPSTVYVDLRALRN 810
E R L F F+A G A +G G+ P VD AL
Sbjct: 307 EPIRRDTL-ERFHDAFTASGFRRTAFYPCYGLAEATLAVTGGSLDAAPLCCSVDNVALEQ 365
Query: 811 DRVSLVERGSPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNASGYFT 870
RV G+ S ++ G +V+ +PET+ +GE WV+ P A GY
Sbjct: 366 GRVIETSEGASGSTAIVGCGVAGLDTEVVIVDPETRQLAAAGQIGEAWVRGPGVARGYL- 424
Query: 871 IYGDESDYADHFSAQLVTGNTGEVYARTGYLGFLRRTEI 909
G + + F A L TG + RTG L F + E+
Sbjct: 425 --GRPEETQESFQAHLDTG--AGPFLRTGDLAFKKGEEL 459
Score = 70.1 bits (164), Expect = 3e-10
Identities = 88/366 (24%), Positives = 151/366 (41%), Gaps = 19/366 (5%)
Query: 29 ETGLWHAVLASVLNG-MHVIFIPYALMKVSPASWMHMITKHRASIAIVKS--RDLHWGLL 85
+ GL + VL V G + V+ P A ++ P W+ I++++A+ + + DL +
Sbjct: 228 DMGLINGVLEPVYAGCLSVMMSPLAFIR-RPRRWLEAISRYQATHSGGPNFAYDLCVRKI 286
Query: 86 ATRDHKEISLSSLRMLLVADGANPWSLSSCDQFLSVFQSKGVRGDAICPCACSSESMTVC 145
RD + + L S R ++ A P + ++F F + G R A PC +E+ T+
Sbjct: 287 PPRDRQGLELGSWRQAYLS--AEPIRRDTLERFHDAFTASGFRRTAFYPCYGLAEA-TLA 343
Query: 146 IXXXXXXXXXXXXXVLSMSGLSYGVVRVDAENSLTSLTLQDCGQVMPSCVIVVVKMEGPA 205
+ V +++ L G V +E + S + CG +V+V E
Sbjct: 344 VTGGSLDAAPLCCSVDNVA-LEQGRVIETSEGASGSTAIVGCGVAGLDTEVVIVDPE-TR 401
Query: 206 YLCKTDEVGEICVLSGATGSGYWGLPGLTNTVFRVRPLDSDGEPIGEEHYVRSXXXXXXX 265
L ++GE V GY G P T F+ LD+ P ++R+
Sbjct: 402 QLAAAGQIGEAWVRGPGVARGYLGRPEETQESFQAH-LDTGAGP-----FLRTGDLAFKK 455
Query: 266 XXXXXXXXXSRDGLMTVTGRKHNMDDIIATVLAVEPMKFIYRGRIAVFSVRVLRDERICI 325
+D ++ + GR ++ DI +V P + G A F V E++ +
Sbjct: 456 GEELFIVGRLKD-VIIIRGRNYHPHDIEWSVGQSHPA--LRAGCAAAFVVDGDGSEKLIV 512
Query: 326 VAE-QRPDCGEEESFQWMSRVLQAVDSIHQVGIYCLALVQPNFLPKTPLGGIHLSECKRR 384
V E QR G + + V QAV H + ++ LV+ +P+T G I C+
Sbjct: 513 VQELQRELSGAAPLEEVIGNVRQAVSEQHGLRLHRAVLVKTGGIPRTSSGKIQRRLCRSL 572
Query: 385 FLEGTL 390
F G+L
Sbjct: 573 FEAGSL 578
Score = 39.9 bits (89), Expect = 0.36
Identities = 19/41 (46%), Positives = 27/41 (65%), Gaps = 1/41 (2%)
Query: 950 DAVFVVGALDETIMLRGMRYHPIDIENSVMRCHKKI-AECA 989
+ +F+VG L + I++RG YHP DIE SV + H + A CA
Sbjct: 457 EELFIVGRLKDVIIIRGRNYHPHDIEWSVGQSHPALRAGCA 497
>UniRef50_Q21WI4 Cluster: AMP-dependent synthetase and ligase; n=1;
Rhodoferax ferrireducens T118|Rep: AMP-dependent
synthetase and ligase - Rhodoferax ferrireducens (strain
DSM 15236 / ATCC BAA-621 / T118)
Length = 958
Score = 125 bits (302), Expect = 6e-27
Identities = 111/422 (26%), Positives = 184/422 (43%), Gaps = 22/422 (5%)
Query: 453 QFISQILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDH 512
Q + + W Q D V+ TL G + L AELH++A + L G ++ GD
Sbjct: 140 QTLVDVFEWHLQHHPDRVLITLYE-NGDQAVDLRYAELHREAVALAAGLRALG-LDKGDK 197
Query: 513 VALIFPPGLDLICAFYGCLYVGAVPVTIRPP-HPQNLHTTLPTVRMIVDVSKATLVLSNQ 571
VA++ P G + AF+G LY G VPV + PP P L L + IV ++A ++++ +
Sbjct: 198 VAIMLPTGREFFAAFFGTLYAGLVPVPLYPPARPSQLEDHLKRIAAIVRNAQARVLVTVE 257
Query: 572 SVIKLLRSKEASNVLDSKAWPMTL--DTDDMPKKKLPIMYRAPTAEMLAYLDFSVSTTGM 629
R+K S +L ++A + D+ P M A TA +A+L ++ +TG
Sbjct: 258 ------RAKPLSQLLRAQAEALQFVRTVADLSLADAPRMQPALTASDIAFLQYTSGSTGD 311
Query: 630 LAGIKMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIP 689
G+ ++HA + + R+M A ++ S L Y +G CL ++Y G H +L+
Sbjct: 312 PKGVILTHANLLANLRAMWRASQVGSSDTFVSWLPLYHDMGLIGACLGALYLGFHLVLMS 371
Query: 690 PSEVEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVV 749
P PA WL + +++ + ELC S + + G++L+C R
Sbjct: 372 PLAFLARPARWLETIHRHRGTVSAAPNFAYELCL----SKLTDAELAGLDLSCWRLAFNG 427
Query: 750 AEERPRINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPSTVYVDLRALR 809
AE L F+ F+ A++ +G N G P VD AL
Sbjct: 428 AEPVSPDTL-ERFAARFAPCSFKREALTPVYGLAENTVGLAFGPVGRGPLVDRVDRAALA 486
Query: 810 NDRVSLVER-GSPHSLCLMESGKLLPG--VKVITANPETKGQCGDSHLGEIWVQSPHNAS 866
D V+ R +L ++ G LPG ++V+ A + + G + + P +
Sbjct: 487 RDGVAEPARPDDAQALRIVSCGSPLPGHELRVVGAGGR---ELPEREQGRVQFRGPSSTQ 543
Query: 867 GY 868
GY
Sbjct: 544 GY 545
Score = 50.0 bits (114), Expect = 3e-04
Identities = 82/393 (20%), Positives = 142/393 (36%), Gaps = 25/393 (6%)
Query: 1 MLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLASVLNGMHVIFIPYALMKVSPAS 60
+LA+ R + A + V L + GL A L ++ G H++ + PA
Sbjct: 322 LLANLRAMWRASQVGSSDTFVSWLPLYHDMGLIGACLGALYLGFHLVLMSPLAFLARPAR 381
Query: 61 WMHMITKHRASIAIVKSRDLHWGLLATRDHKEISLSSLRMLLVADGANPWSLSSCDQFLS 120
W+ I +HR +++ + L D + L L +GA P S + ++F +
Sbjct: 382 WLETIHRHRGTVSAAPNFAYELCLSKLTDAELAGLDLSCWRLAFNGAEPVSPDTLERFAA 441
Query: 121 VFQSKGVRGDAICPCACSSESMTVCIXXXXXXXXXXXXXVLSMSGLSYGVVRVDAENSLT 180
F + +A+ P +E+ TV + V + GV +
Sbjct: 442 RFAPCSFKREALTPVYGLAEN-TVGLAFGPVGRGPLVDRVDRAALARDGVAEPARPDDAQ 500
Query: 181 SLTLQDCGQVMPSCVIVVVKMEGPAYLCKTDEVGEICVLSGATGSGYWGLPGLTNTVFRV 240
+L + CG +P + VV G E G + ++ GY L N V
Sbjct: 501 ALRIVSCGSPLPGHELRVVGAGGRE--LPEREQGRVQFRGPSSTQGY-----LNNPVANQ 553
Query: 241 RPLDSDGEPIGEEHYVRSXXXXXXXXXXXXXXXXSRDGLMTVTGRKHNMDDIIATVLAVE 300
R LD D G+ Y+ + R G ++ +A + V
Sbjct: 554 RLLDGDWLNTGDLGYIAAAELFLTGREKDIII---RGGFNI---HPQELESAVANIAGVR 607
Query: 301 PMKFIYRGRIAVFSVRVLRD--ERICIVAEQRPDCGEEESFQWMSRVLQAVD-SIHQVGI 357
+G +AVF+ R ER+ ++AE R E M R + A+ ++
Sbjct: 608 ------KGGVAVFAATDRRSGTERLVVLAETR--VREPAQRAQMIRAITALSATLLGAPA 659
Query: 358 YCLALVQPNFLPKTPLGGIHLSECKRRFLEGTL 390
+ L P + KT G + C+ + +G L
Sbjct: 660 DDVVLAPPRSVLKTSSGKTRRAACRELYEQGRL 692
>UniRef50_Q1D591 Cluster: Nonribosomal peptide synthetase; n=1;
Myxococcus xanthus DK 1622|Rep: Nonribosomal peptide
synthetase - Myxococcus xanthus (strain DK 1622)
Length = 1777
Score = 125 bits (301), Expect = 7e-27
Identities = 114/453 (25%), Positives = 186/453 (41%), Gaps = 21/453 (4%)
Query: 460 RWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPP 519
R RA + D I+T L+ G + ++ AEL A + LL + + G+ L++PP
Sbjct: 26 RARAAAQPDDWIYTFLDEAG--EQAVSYAELDASARAVAALL--QRHLAPGERALLLYPP 81
Query: 520 GLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRS 579
G D F CLY G V V PP P L TLP ++ +V A + L+ + ++
Sbjct: 82 GRDYTLGFLACLYAGVVAVPAYPPDPMRLGRTLPRLQALVADCGARVALTTSGIADMVEP 141
Query: 580 -KEASNVLDSKAWPMTLDTDDMPKKKLPIMYRAPT--AEMLAYLDFSVSTTGMLAGIKMS 636
+ + L + W L TD + + + +RAP + +A+L ++ +TG G+ +
Sbjct: 142 LTQGAPDLRALRW---LATDSVFQHEAE-AWRAPVLRGDSVAFLQYTSGSTGTPRGVVLR 197
Query: 637 HAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIPPSEVEVN 696
H + + + P AL L PY +G + ++Y S+L+PP
Sbjct: 198 HRHLLHNSWLIARGFDTRPHPVAALWLPPYHDMGLIGGLIQALYRDIPSVLLPPMSFLHR 257
Query: 697 PALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVVAEERPRI 756
P WL A+S++ +LC + + ++L+ + AE R
Sbjct: 258 PLRWLEAMSRFGATVCGAPNFAFDLCVR----KTTPEQRAALDLSRLEVAFSGAEP-VRA 312
Query: 757 NLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPSTVYVDLRALRNDRVSLV 816
+ + F F+ G A +G I G S P L
Sbjct: 313 DTLDRFVDAFAPAGFRREAFYPCYGLAEGTLIVSGGTRSAVPVVRRFARDGLLRGEARAP 372
Query: 817 ERGSPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNASGYFTIYGDES 876
E +P + L+ G+ L G V +PET C +GE+WV+ P A GY+ DE+
Sbjct: 373 EVDAP-ATALVGCGQALGGQDVRVVDPETGRPCAPGRVGELWVRGPSVADGYWQ-RPDET 430
Query: 877 DYADHFSAQLVTGNTGEVYARTGYLGFLRRTEI 909
+ F +L G Y RTG L + E+
Sbjct: 431 ERT--FHGRLAGSGEGP-YLRTGDLAVIDGGEV 460
Score = 74.9 bits (176), Expect = 1e-11
Identities = 78/363 (21%), Positives = 134/363 (36%), Gaps = 13/363 (3%)
Query: 29 ETGLWHAVLASVLNGMHVIFIPYALMKVSPASWMHMITKHRASIAIVKSRDLHWGLLATR 88
+ GL ++ ++ + + +P P W+ +++ A++ + + T
Sbjct: 229 DMGLIGGLIQALYRDIPSVLLPPMSFLHRPLRWLEAMSRFGATVCGAPNFAFDLCVRKTT 288
Query: 89 DHKEISLSSLRMLLVADGANPWSLSSCDQFLSVFQSKGVRGDAICPCACSSESMTVCIXX 148
+ +L R+ + GA P + D+F+ F G R +A PC +E I
Sbjct: 289 PEQRAALDLSRLEVAFSGAEPVRADTLDRFVDAFAPAGFRREAFYPCYGLAEG--TLIVS 346
Query: 149 XXXXXXXXXXXVLSMSGLSYGVVRVDAENSLTSLTLQDCGQVMPSCVIVVVKMEGPAYLC 208
+ GL G R E + L CGQ + + VV E C
Sbjct: 347 GGTRSAVPVVRRFARDGLLRGEARAP-EVDAPATALVGCGQALGGQDVRVVDPE-TGRPC 404
Query: 209 KTDEVGEICVLSGATGSGYWGLPGLTNTVFRVRPLDSDGEPIGEEHYVRSXXXXXXXXXX 268
VGE+ V + GYW P T F R S GE Y+R+
Sbjct: 405 APGRVGELWVRGPSVADGYWQRPDETERTFHGRLAGS-----GEGPYLRTGDLAVIDGGE 459
Query: 269 XXXXXXSRDGLMTVTGRKHNMDDIIATVLAVEPMKFIYRGRIAVFSVRVLRDERICIVAE 328
+D ++ + G + D+ P + G A F+V +ER+ IV E
Sbjct: 460 VFITGRLKD-VLVLRGLNYYPQDLEHAADRCHPG--VRPGCGAAFAVDAGDEERLVIVQE 516
Query: 329 QRPDCGEEESF-QWMSRVLQAVDSIHQVGIYCLALVQPNFLPKTPLGGIHLSECKRRFLE 387
E+ + ++ + A+ H + ++ + L+ LPKT G + + FL
Sbjct: 517 VAAKVATPEAAAEVVASIRAALGEAHGLAVHAVVLITAGTLPKTSSGKVQRRATREAFLA 576
Query: 388 GTL 390
GTL
Sbjct: 577 GTL 579
Score = 40.3 bits (90), Expect = 0.27
Identities = 14/31 (45%), Positives = 23/31 (74%)
Query: 952 VFVVGALDETIMLRGMRYHPIDIENSVMRCH 982
VF+ G L + ++LRG+ Y+P D+E++ RCH
Sbjct: 460 VFITGRLKDVLVLRGLNYYPQDLEHAADRCH 490
>UniRef50_Q0LP47 Cluster: AMP-dependent synthetase and ligase; n=1;
Herpetosiphon aurantiacus ATCC 23779|Rep: AMP-dependent
synthetase and ligase - Herpetosiphon aurantiacus ATCC
23779
Length = 579
Score = 124 bits (300), Expect = 1e-26
Identities = 112/457 (24%), Positives = 198/457 (43%), Gaps = 29/457 (6%)
Query: 457 QILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVALI 516
+I+ RA++T + + A G + L+ L ++ + I +L + GD L+
Sbjct: 26 EIILQRAKTTPEAIALNFYTADGYRTS-LSYGLLAQRCQAIAAVLQRVTK--PGDRALLL 82
Query: 517 FPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKL 576
+PPGL + AF+GCL+ G + V PP P L I+ ++A ++L+ V+
Sbjct: 83 YPPGLGYVEAFFGCLFAGVIAVPAYPPRPNRRDQRL---EAIISNAQARVMLAASEVVAQ 139
Query: 577 LRS-KEASNVLDSKAWPMTLDTDDMPKKKLPIMYRAPTAEM--LAYLDFSVSTTGMLAGI 633
R+ + L W D+ +L M++AP+ LA+L ++ +T G+
Sbjct: 140 QRALSQQYPGLAQLQW----IASDLVNSQLASMWQAPSINTHDLAFLQYTSGSTSQPRGV 195
Query: 634 KMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIPPSEV 693
+SH + + + + H+ + L PY +G + +++G LI P
Sbjct: 196 MVSHENLVYNSGLIAQSFGITADDHVFIWLPPYHDMGLIGGIMQPLFTGCELSLIDPLTF 255
Query: 694 EVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVVAEER 753
P +WL +S V T +LC + G++L+ +R AE
Sbjct: 256 LQQPLIWLRMISDLGVTVTGGPNFAYDLCV----AKAKPEALAGVDLSRLRVAFNGAEP- 310
Query: 754 PRINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGA-SSPEPSTVYVDLRALRNDR 812
R FS+ F+ LG P+A +G + + GA + EP+T+ VD +AL +
Sbjct: 311 IRAATLERFSRTFAPLGFKPQAFLPCYGL-AEATLFVSGAPHAAEPTTLTVDAQALSQHQ 369
Query: 813 VSLVERGSPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNASGYFTIY 872
ERG+ L+ SG + V +PE C D +GE+ + A GY+
Sbjct: 370 ALPSERGT----LLVSSGMVAAPQIVAIVDPEQGQVCADGWVGEVCIHGRSIAHGYW--- 422
Query: 873 GDESDYADHFSAQLVTGNTGEVYARTGYLGFLRRTEI 909
++ A + QL+ + + RTG LGF+ ++
Sbjct: 423 --DNSAASEATFQLILPDGSGPFLRTGDLGFIHEGQL 457
Score = 79.8 bits (188), Expect = 4e-13
Identities = 88/390 (22%), Positives = 153/390 (39%), Gaps = 29/390 (7%)
Query: 7 MLSVACNYTEGEHMVCVLDFKRETGLWHAVLASVLNGMHVIFIPYALMKVSPASWMHMIT 66
+++ + T +H+ L + GL ++ + G + I P W+ MI+
Sbjct: 208 LIAQSFGITADDHVFIWLPPYHDMGLIGGIMQPLFTGCELSLIDPLTFLQQPLIWLRMIS 267
Query: 67 KHRASIAIVKSRDLHWGLLATRDHKE----ISLSSLRMLLVADGANPWSLSSCDQFLSVF 122
+ + + + L + E + LS LR+ +GA P ++ ++F F
Sbjct: 268 D--LGVTVTGGPNFAYDLCVAKAKPEALAGVDLSRLRVAF--NGAEPIRAATLERFSRTF 323
Query: 123 QSKGVRGDAICPCACSSESMTVCIXXXXXXXXXXXXXVLSMSGLSYGVVRVDAENSLTSL 182
G + A PC +E+ T+ + V LS +L
Sbjct: 324 APLGFKPQAFLPCYGLAEA-TLFVSGAPHAAEPTTLTV-DAQALSQHQALPSERGTL--- 378
Query: 183 TLQDCGQVMPSCVIVVVKMEGPAYLCKTDEVGEICVLSGATGSGYWGLPGLTNTVFRVRP 242
L G V ++ +V E +C VGE+C+ + GYW + F++
Sbjct: 379 -LVSSGMVAAPQIVAIVDPE-QGQVCADGWVGEVCIHGRSIAHGYWDNSAASEATFQLIL 436
Query: 243 LDSDGEPIGEEHYVRSXXXXXXXXXXXXXXXXSRDGLMTVTGRKHNMDDIIATVLAVEPM 302
D G ++R+ +D L+ + GR H D+ +V P
Sbjct: 437 PDGSGP------FLRTGDLGFIHEGQLYITGRLKD-LIIIDGRNHYPQDLELSVELAHPA 489
Query: 303 KFIYRGRIAVFSVRVLRDERICIVAE-QRPDCGEEESFQWMSRVLQAVDSIHQVGIYCLA 361
I +G A F+V E+I IVAE +RP+ EE + V A+ + + I L
Sbjct: 490 --IRQGGCAAFAVDGADGEQIVIVAEIRRPNQAEEAA----QAVRLALQQQYDLAIADLM 543
Query: 362 LVQPNFLPKTPLGGIHLSECKRRFLEGTLH 391
V+P +PKT G + EC++R+L TL+
Sbjct: 544 WVRPGQVPKTSSGKVRRRECRQRYLSQTLN 573
>UniRef50_O54155 Cluster: Polyketide synthase; n=2;
Actinomycetales|Rep: Polyketide synthase - Streptomyces
coelicolor
Length = 2297
Score = 124 bits (299), Expect = 1e-26
Identities = 116/455 (25%), Positives = 186/455 (40%), Gaps = 21/455 (4%)
Query: 455 ISQILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVA 514
++ +LR RA+ T D + L S T EL A + L G V G V
Sbjct: 30 VTALLRHRAEHTPDALAHRFLTDTDGTSVAWTYRELDLHAREVATHLRHAG-VGQGP-VL 87
Query: 515 LIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVI 574
L+ PPGLD + AF+GCLY GAV V PP T+P + I AT L+ + V
Sbjct: 88 LLHPPGLDYLAAFFGCLYAGAVAVPAYPPDNARFGQTVPRLAAIARDCAATHALTTRRVR 147
Query: 575 KLLRSKEASNV---LDSKAWPMTLDTDDMPKKKLPIMYRAP--TAEMLAYLDFSVSTTGM 629
+ + + V LD W L T+D+ + + P TA LA+L ++ +T
Sbjct: 148 ETVAADGTGRVGTELDGVRW---LVTEDLYTGESTTAWEDPGATARSLAFLQYTSGSTAA 204
Query: 630 LAGIKMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIP 689
G+ + H + RS+ + + L PY +G L+ +Y G + L+
Sbjct: 205 PKGVMVEHGNLVRNLRSIHLRLGHDADSGMVSWLPPYHDMGLIGGILTPVYGGFPAHLMA 264
Query: 690 PSEVEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVV 749
P P LWL +S+ + E C + + + G++L+ R +
Sbjct: 265 PMTFVQRPLLWLETLSRTGASTSVAPNFGFEQCLR----RITPAQRAGLDLSRWRLALNG 320
Query: 750 AEERPRINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPSTV-YVDLRAL 808
AE R + + F++ F+ G A+ +G + + G +P V D AL
Sbjct: 321 AEP-IRPDTLDRFAEYFAPAGFDRTALLPCYGL-AEATLMVTGVRPADPPVVESFDAAAL 378
Query: 809 RNDRVSLVERGSPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNASGY 868
+ G + ++ G + V+V + T + D + EI V P A GY
Sbjct: 379 EAGTARPADPGGVRTTRVVGCGAPVADVEVAVVDAATGRRVPDGTVAEIRVSGPGVARGY 438
Query: 869 FTIYGDESDYADHFSAQLVTGNTGEVYARTGYLGF 903
+G A+ F + + G G + RTG +GF
Sbjct: 439 ---WGRPEAAAEVFGTR-IDGEPGNAWLRTGDVGF 469
Score = 66.9 bits (156), Expect = 3e-09
Identities = 81/388 (20%), Positives = 142/388 (36%), Gaps = 14/388 (3%)
Query: 1 MLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLASVLNGMHVIFIPYALMKVSPAS 60
++ + R + + + MV L + GL +L V G + P
Sbjct: 215 LVRNLRSIHLRLGHDADSGMVSWLPPYHDMGLIGGILTPVYGGFPAHLMAPMTFVQRPLL 274
Query: 61 WMHMITKHRASIAIVKSRDLHWGLLATRDHKEISLSSLRMLLVADGANPWSLSSCDQFLS 120
W+ +++ AS ++ + L + L R L +GA P + D+F
Sbjct: 275 WLETLSRTGASTSVAPNFGFEQCLRRITPAQRAGLDLSRWRLALNGAEPIRPDTLDRFAE 334
Query: 121 VFQSKGVRGDAICPCACSSESMTVCIXXXXXXXXXXXXXVLSMSGLSYGVVRVDAENSLT 180
F G A+ PC +E+ T+ + + L G R +
Sbjct: 335 YFAPAGFDRTALLPCYGLAEA-TLMVTGVRPADPPVVES-FDAAALEAGTARPADPGGVR 392
Query: 181 SLTLQDCGQVMPSCVIVVVKMEGPAYLCKTDEVGEICVLSGATGSGYWGLPGLTNTVFRV 240
+ + CG + + VV V EI V GYWG P VF
Sbjct: 393 TTRVVGCGAPVADVEVAVVD-AATGRRVPDGTVAEIRVSGPGVARGYWGRPEAAAEVFGT 451
Query: 241 RPLDSDGEPIGEEHYVRSXXXXXXXXXXXXXXXXSRDGLMTVTGRKHNMDDIIATVLAVE 300
R DGEP ++R+ ++D ++ V GR + D+ T V
Sbjct: 452 R---IDGEP--GNAWLRTGDVGFRHDGQLYVVGRTKD-VIIVQGRNIHPQDVEQTAERVG 505
Query: 301 PMKFIYRGRIAVFSVRVLRDERICIVAE-QRPDCGEEESFQWMSRVLQAVDSIHQVGIYC 359
+ G A F+V E++ + E P G+ + ++R+ A+ HQV +
Sbjct: 506 --AGLRAGYGAAFAVPTADGEQLALAYEIGGPGAGDPHAL--LARLRTAIADEHQVTPHT 561
Query: 360 LALVQPNFLPKTPLGGIHLSECKRRFLE 387
+ L++ + +P+T G I C++R L+
Sbjct: 562 VVLLKRSSVPRTTSGKIQRGACRQRLLD 589
>UniRef50_Q50857 Cluster: Saframycin Mx1 synthetase B; n=1;
Myxococcus xanthus|Rep: Saframycin Mx1 synthetase B -
Myxococcus xanthus
Length = 1770
Score = 124 bits (299), Expect = 1e-26
Identities = 120/463 (25%), Positives = 204/463 (44%), Gaps = 29/463 (6%)
Query: 457 QILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVALI 516
++L+ RA S H FT L G + + + + A I L GRV G+ L+
Sbjct: 25 ELLQERALSEPRHEAFTFLGEAGVPAVRVDYSSMDVLARAIAARLQADGRV--GERALLL 82
Query: 517 FPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKL 576
+ PG + + AF+GCLY G V V + PP L +L +R + S+A++VL+ + L
Sbjct: 83 YAPGPEYVAAFFGCLYAGVVAVPVYPPDTARLERSLLRLRTVARDSRASVVLTTSFLQGL 142
Query: 577 LRSK-EASNVLDSKAWPMTLDTDDMPKKKLPIMYRAP--TAEMLAYLDFSVSTTGMLAGI 633
+ E + L +W + TD + ++ ++ P + + +A+L ++ +T G+
Sbjct: 143 AGAMFELAPELGELSW---VATDGIALEEAG-AWKPPGLSGDSVAFLQYTSGSTADPKGV 198
Query: 634 KMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIPPSEV 693
++H + + +L + L PY +G L+ I+ G L+ P
Sbjct: 199 VLTHRNLMHNLSVIHERFQLNRGSRGVIWLPPYHDMGLIGGVLTPIFGGLPVDLMSPLSF 258
Query: 694 EVNPALWLSAVSQYKVRDTFCSYG---VMELCTKGLGSSVNQLKSKGINLACVRTCVVVA 750
P WL +S+ R CS G ELC + ++ + G++L+ A
Sbjct: 259 LQEPLRWLKTLSE---RRGTCSGGPNFAYELCVR----KISDEQKAGLDLSSWELAFCGA 311
Query: 751 EERPRINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPSTV-YVDLRALR 809
E R + +FSK F G A +G I + G S + V + AL
Sbjct: 312 EP-IRPDTLEAFSKAFEPCGFRREAFYPCYGLAEGTLI-VTGVSKGRAARVEHFQREALE 369
Query: 810 NDR---VSLVERGSPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNAS 866
R S + ++ + G ++P +++ +PET+ H+GEIWV+ P A
Sbjct: 370 AHRAVAASSPGEAARDTVRHVSCGTVVPDEQILVVDPETRTALPPGHIGEIWVRGPSVAQ 429
Query: 867 GYFTIYGDESDYADHFSAQLVTGNTGEVYARTGYLGFLRRTEI 909
GY+ + +E+ A F A+L G T + RTG LGFL E+
Sbjct: 430 GYW-LRPEET--ARTFQARL-AGGTEAPWLRTGDLGFLHDGEL 468
Score = 66.1 bits (154), Expect = 5e-09
Identities = 77/365 (21%), Positives = 138/365 (37%), Gaps = 14/365 (3%)
Query: 29 ETGLWHAVLASVLNGMHV-IFIPYALMKVSPASWMHMITKHRASIAIVKSRDLHWGLLAT 87
+ GL VL + G+ V + P + ++ P W+ +++ R + + + +
Sbjct: 233 DMGLIGGVLTPIFGGLPVDLMSPLSFLQ-EPLRWLKTLSERRGTCSGGPNFAYELCVRKI 291
Query: 88 RDHKEISLSSLRMLLVADGANPWSLSSCDQFLSVFQSKGVRGDAICPCACSSESMTVCIX 147
D ++ L L GA P + + F F+ G R +A PC +E T+ +
Sbjct: 292 SDEQKAGLDLSSWELAFCGAEPIRPDTLEAFSKAFEPCGFRREAFYPCYGLAEG-TLIVT 350
Query: 148 XXXXXXXXXXXXVLSMSGLSYGVVRVDAENSLTSLTLQ--DCGQVMPSCVIVVVKMEGPA 205
+ ++ V + T++ CG V+P I+VV E
Sbjct: 351 GVSKGRAARVEHFQREALEAHRAVAASSPGEAARDTVRHVSCGTVVPDEQILVVDPETRT 410
Query: 206 YLCKTDEVGEICVLSGATGSGYWGLPGLTNTVFRVRPLDSDGEPIGEEHYVRSXXXXXXX 265
L +GEI V + GYW P T F+ R P ++R+
Sbjct: 411 AL-PPGHIGEIWVRGPSVAQGYWLRPEETARTFQARLAGGTEAP-----WLRTGDLGFLH 464
Query: 266 XXXXXXXXXSRDGLMTVTGRKHNMDDIIATVLAVEPMKFIYRGRIAVFSVRVLRDERICI 325
+D L+ + GR + D+ TV P + G AVFSV V E + +
Sbjct: 465 DGELFVSGRRKD-LLVIRGRNYYPQDLELTVERSHPA--LRPGCAAVFSVSVGASEEVVV 521
Query: 326 VAEQRPDCGEEESFQWMSRVLQAVDSIHQVGIYCLALVQPNFLPKTPLGGIHLSECKRRF 385
V E + ++ + + + H + ++ + L++ L KT G + + +
Sbjct: 522 VQEVDRRYPGGDWPDVIAAIRRDISEQHALRVHAVVLIKSGSLLKTSSGKVQRGATREAY 581
Query: 386 LEGTL 390
LEG L
Sbjct: 582 LEGQL 586
>UniRef50_Q090E5 Cluster: Beta-ketoacyl synthase; n=1; Stigmatella
aurantiaca DW4/3-1|Rep: Beta-ketoacyl synthase -
Stigmatella aurantiaca DW4/3-1
Length = 624
Score = 123 bits (297), Expect = 2e-26
Identities = 115/456 (25%), Positives = 184/456 (40%), Gaps = 21/456 (4%)
Query: 458 ILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIF 517
+LR R + ++ G V LT AEL ++A + L + G L++
Sbjct: 51 LLRLRCLEQPHQLAYSYETDHGEVR--LTYAELDRQARTVAAQL--QAANGAGARALLLY 106
Query: 518 PPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKAT---LVLSNQSVI 574
PG D + F+GCLY G + V PP VR I +++ V++ +V
Sbjct: 107 HPGPDFLAGFFGCLYAGVIAVPAYPPRAP-FRPDDRNVRRIFSIAQDASPRFVITTDAVR 165
Query: 575 KLLRSKEASNVLDSKAWPMTLDTDDMPKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIK 634
LR + S VL + D + P + + P + LA+L ++ +TG G+
Sbjct: 166 TKLR--DISGVLPGIEQWLASDVQEGPGAEAWSSF-TPHQDDLAFLQYTSGSTGTPKGVM 222
Query: 635 MSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIPPSEVE 694
+SH + + R + + + I L + +G L +Y G L+ P
Sbjct: 223 VSHGNIIANERMITVGFGMSEKTRIGGWLPVFHDMGLIGHVLQPMYLGVPCFLMSPMSFM 282
Query: 695 VNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVVAEERP 754
P WL +S R+ G + + +V++ + ++L+C AE
Sbjct: 283 KRPYRWLDLIS----RNRLTVSGAPDFAYRFCVEAVSEEEKARLDLSCWELAFNGAEP-V 337
Query: 755 RINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPSTVYVDLRALRNDRVS 814
R SFS F++ G ++GC G P + V L R
Sbjct: 338 RTETLESFSAAFASCGFRKNTFYPTYGCAEATLFVAGGQKEALPVKLVVKRSELERGRAV 397
Query: 815 LVERGSPHSL-CLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNASGYFTIYG 873
G L L+ GK G K+ +PET+ Q + H+GEIWV P+ GY+
Sbjct: 398 EAAEGETQDLRVLVGCGKSAVGQKLAIVHPETRVQAEEGHVGEIWVSGPNVTGGYWNRV- 456
Query: 874 DESDYADHFSAQLVTGNTGEVYARTGYLGFLRRTEI 909
ES+ + F A L G++ Y RTG LGFL E+
Sbjct: 457 QESE--ERFRAPLADGDSRLCY-RTGDLGFLLNGEL 489
Score = 64.5 bits (150), Expect = 1e-08
Identities = 90/395 (22%), Positives = 156/395 (39%), Gaps = 18/395 (4%)
Query: 1 MLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLASVLNGMHVIFI-PYALMKVSPA 59
++A+ RM++V +E + L + GL VL + G+ + P + MK P
Sbjct: 228 IIANERMITVGFGMSEKTRIGGWLPVFHDMGLIGHVLQPMYLGVPCFLMSPMSFMK-RPY 286
Query: 60 SWMHMITKHRASIAIVKSRDLHWGLLATRDHKEISLSSLRMLLVADGANPWSLSSCDQFL 119
W+ +I+++R +++ + + A + ++ L L +GA P + + F
Sbjct: 287 RWLDLISRNRLTVSGAPDFAYRFCVEAVSEEEKARLDLSCWELAFNGAEPVRTETLESFS 346
Query: 120 SVFQSKGVRGDAICPC-ACSSESMTVCIXXXXXXXXXXXXXVLSMSGLSYGVVRVDAENS 178
+ F S G R + P C+ ++ V V+ S L G AE
Sbjct: 347 AAFASCGFRKNTFYPTYGCAEATLFVA---GGQKEALPVKLVVKRSELERGRAVEAAEGE 403
Query: 179 LTSL-TLQDCGQVMPSCVIVVVKMEGPAYLCKTDEVGEICVLSGATGSGYWGLPGLTNTV 237
L L CG+ + +V E + VGEI V GYW +
Sbjct: 404 TQDLRVLVGCGKSAVGQKLAIVHPETRVQ-AEEGHVGEIWVSGPNVTGGYWNRVQESEER 462
Query: 238 FRVRPLDSDGEPIGEEHYVRSXXXXXXXXXXXXXXXXSRDGLMTVTGRKHNMDDIIATVL 297
FR PL +DG+ R+ + D L+ + G H +DI TV
Sbjct: 463 FRA-PL-ADGD---SRLCYRTGDLGFLLNGELFITGRASD-LIIIRGLNHYPEDIELTVG 516
Query: 298 AVEPMKFIYRGRIAVFSVRVLRDERICIVAEQRPDCGEEESFQWMSRVLQAVDSIHQVGI 357
+V F+ + S+ V +ER+ +V E + ++ Q V +A+ H + +
Sbjct: 517 SVNE-HFLMSCAV---SIDVDGEERVVVVQEVSREFPDDGFDQAGMSVRRALSEAHGLEL 572
Query: 358 YCLALVQPNFLPKTPLGGIHLSECKRRFLEGTLHP 392
+ L L+ LP+T G + C+ L+G L P
Sbjct: 573 HSLILLPRGRLPRTSSGKVQRRVCRELLLKGGLDP 607
>UniRef50_UPI000038CE97 Cluster: COG0318: Acyl-CoA synthetases
(AMP-forming)/AMP-acid ligases II; n=1; Nostoc
punctiforme PCC 73102|Rep: COG0318: Acyl-CoA synthetases
(AMP-forming)/AMP-acid ligases II - Nostoc punctiforme
PCC 73102
Length = 1284
Score = 123 bits (296), Expect = 3e-26
Identities = 116/468 (24%), Positives = 198/468 (42%), Gaps = 24/468 (5%)
Query: 451 KYQFISQILRWRAQSTSDHVIFT-LLNAKGAVSKV-LTCAELHKKAERIG---NLLLEKG 505
+++ + ++L RA+ + +T LL+ + + ++ EL ++A I ++ G
Sbjct: 4 QFKDLVELLLTRAKEQPSRIAYTFLLDGEDESQSIQISYQELDRQARAIAIHLQSIMNAG 63
Query: 506 RVNTGD--HVALIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSK 563
V G +++P GLD I AF+GCLY G VP+ P +P + L + IV ++
Sbjct: 64 DVYDGQSPRALMLYPAGLDFITAFFGCLYAGIVPI---PAYPPRQNHKLSRLEAIVLDAE 120
Query: 564 ATLVLSNQSVIKLLRS-KEASNVLDSKAWPMTLDTDDMPKKKLPIMYRAP-TAEMLAYLD 621
A +VL+ V+ L+ + S+ L W L T+D+ R E LA+L
Sbjct: 121 AKIVLTTSGVMANLKDIGKYSSALAEIEW---LPTNDLILGDGSSWVRPEINGETLAFLQ 177
Query: 622 FSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYS 681
++ +TG G+ ++H + + + + + I L + +G L +Y
Sbjct: 178 YTSGSTGTPKGVMVTHDNLLRNSADLDLGWDHDENSVIVTWLPTFHDMGLIYGMLQPLYK 237
Query: 682 GHHSILIPPSEVEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLA 741
G ++ P P WL A+S+Y+ + +LC + + + ++K ++L+
Sbjct: 238 GCTCYMMAPVSFLQKPIRWLQAISRYRGTHSGAPNFAYKLCAEKI---TPEQRAK-LDLS 293
Query: 742 CVRTCVVVAEERPRINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPSTV 801
R + AE R ++ F + F G RA +G S P +
Sbjct: 294 SWRMALNGAEP-VRADVLEEFVEAFKPSGFDGRAFCPGYGLAEATLKVSAVRSKDLPVYL 352
Query: 802 YVDLRALRNDRVSLVERGSPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQS 861
+VD AL RV V P + G +++ NPET Q GD +GEIW
Sbjct: 353 HVDAEALEQHRVVEVSANHPRCRQFVGCGWTEIDTQIVIVNPETLTQRGDDEVGEIWASG 412
Query: 862 PHNASGYFTIYGDESDYADHFSAQLVTGNTGEVYARTGYLGFLRRTEI 909
GY + A+ F A L G Y RTG LGF+ E+
Sbjct: 413 STIPLGY---WNRPEATAETFQAYLKDTKAGP-YLRTGDLGFVHNGEL 456
Score = 82.6 bits (195), Expect = 5e-14
Identities = 92/393 (23%), Positives = 155/393 (39%), Gaps = 16/393 (4%)
Query: 1 MLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLASVLNGMHVIFIPYALMKVSPAS 60
+L + L + ++ E +V L + GL + +L + G + P
Sbjct: 196 LLRNSADLDLGWDHDENSVIVTWLPTFHDMGLIYGMLQPLYKGCTCYMMAPVSFLQKPIR 255
Query: 61 WMHMITKHRA--SIAIVKSRDLHWGLLATRDHKEISLSSLRMLLVADGANPWSLSSCDQF 118
W+ I+++R S A + L + ++ LSS RM L +GA P ++F
Sbjct: 256 WLQAISRYRGTHSGAPNFAYKLCAEKITPEQRAKLDLSSWRMAL--NGAEPVRADVLEEF 313
Query: 119 LSVFQSKGVRGDAICPCACSSESMTVCIXXXXXXXXXXXXXVLSMSGLSYGVVRVDAENS 178
+ F+ G G A CP +E+ T+ + V + + + VV V A N
Sbjct: 314 VEAFKPSGFDGRAFCPGYGLAEA-TLKVSAVRSKDLPVYLHVDAEALEQHRVVEVSA-NH 371
Query: 179 LTSLTLQDCGQVMPSCVIVVVKMEGPAYLCKTDEVGEICVLSGATGSGYWGLPGLTNTVF 238
CG IV+V E DEVGEI GYW P T F
Sbjct: 372 PRCRQFVGCGWTEIDTQIVIVNPETLTQR-GDDEVGEIWASGSTIPLGYWNRPEATAETF 430
Query: 239 RVRPLDSDGEPIGEEHYVRSXXXXXXXXXXXXXXXXSRDGLMTVTGRKHNMDDIIATVLA 298
+ D+ P Y+R+ +D ++ + GR H DI TV
Sbjct: 431 QAYLKDTKAGP-----YLRTGDLGFVHNGELFVTGRIKD-VIIIRGRNHYPQDIELTVEK 484
Query: 299 VEPMKFIYRGRIAVFSVRVLRDERICIVAE-QRPDCGEEESFQWMSRVLQAVDSIHQVGI 357
P + A F+V + +ER+ + E +R + + + + + +AV H++ +
Sbjct: 485 SHPA--LRPTCTAAFTVEIEGEERLIVAQEIERLHLRKLDVEEVVGAIRRAVSQQHELQL 542
Query: 358 YCLALVQPNFLPKTPLGGIHLSECKRRFLEGTL 390
Y + L++ +PKT G I C+ +F+E L
Sbjct: 543 YAVILLKTATIPKTSSGKIQRRTCRAKFVENAL 575
>UniRef50_Q1D3S3 Cluster: Non-ribosomal peptide synthase; n=3;
Bacteria|Rep: Non-ribosomal peptide synthase -
Myxococcus xanthus (strain DK 1622)
Length = 2154
Score = 123 bits (296), Expect = 3e-26
Identities = 118/464 (25%), Positives = 188/464 (40%), Gaps = 24/464 (5%)
Query: 449 ARKYQFISQILRWRAQSTSDHVIFTLLNAKGAVSKV--LTCAELHKKAERIGNLLLEKGR 506
A ++ + +L RA+S D +++ L V T L +A +G L G
Sbjct: 9 AHRFPTLVDVLCQRAESQGDALLYRFLETGDVDGPVEEWTYRRLDSRARSLGARLRALGA 68
Query: 507 VNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATL 566
G+ L++PPGL+ + F GCLY G + V PP P L TLP +R I A
Sbjct: 69 --QGERALLLYPPGLEFVAGFMGCLYGGVIAVPCYPPDPTRLERTLPRLRAIARDCGARY 126
Query: 567 VLSNQSVIKLLR-SKEASNVLDSKAWPMTLDTDDMPKKKLPIMYRAP-TAEMLAYLDFSV 624
VL+ ++ ++ + L W + +D +P+ + R T+E LA+L ++
Sbjct: 127 VLTTSTIQEMAEFLTPQAPELGELQW---IASDAVPEAEAADWKRPDLTSESLAFLQYTS 183
Query: 625 STTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIAL-CLDPYCGLGFALWCLSSIYSGH 683
+TG G+K+SHA + + L R + + L + +G L +Y G
Sbjct: 184 GSTGNPKGVKVSHANILHNESLITRDFGLQAERSVGVGWLPMFHDMGLIGKVLQPLYLGF 243
Query: 684 HSILIPPSEVEVNPALWLSAVSQYKVRDTFCSYGVMELCT-KGLGSSVNQLKSKGINLAC 742
+L+ P P WL AVS +K + +LC K V +L +LA
Sbjct: 244 PCVLMSPIAFLQRPLRWLEAVSHFKGTVSGGPNFAYDLCARKARAEDVARLDLSHWDLA- 302
Query: 743 VRTCVVVAEERPRINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPSTVY 802
E R F++ F+ G A +G I G
Sbjct: 303 -----FNGAEPVRRETMERFAETFAPAGFRREAFYPCYGLAEATLIVSGGVKGTPCVQER 357
Query: 803 VDLRALRNDRVSLVERGS--PHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQ 860
D +L R + P + L+ SG+ P +++ +PET+ + +GE+WV
Sbjct: 358 YDTGSLELGRAKPASDAAEGPTARTLVSSGQGAPDQRLLIVDPETRVPRASNEVGEVWVA 417
Query: 861 SPHNASGYFTIYGDESDYADHFSAQLVTGNTGEVYARTGYLGFL 904
P A GY + + A F A+L G + RTG L FL
Sbjct: 418 GPSVAGGY---WDRPEETAHAFGARLANGE--GPFLRTGDLAFL 456
Score = 72.9 bits (171), Expect = 4e-11
Identities = 85/365 (23%), Positives = 141/365 (38%), Gaps = 16/365 (4%)
Query: 29 ETGLWHAVLASVLNGMH-VIFIPYALMKVSPASWMHMITKHRASIAIVKSRDLHWGLLAT 87
+ GL VL + G V+ P A ++ P W+ ++ + +++ + + L A
Sbjct: 228 DMGLIGKVLQPLYLGFPCVLMSPIAFLQ-RPLRWLEAVSHFKGTVS--GGPNFAYDLCAR 284
Query: 88 RDHKE--ISLSSLRMLLVADGANPWSLSSCDQFLSVFQSKGVRGDAICPCACSSESMTVC 145
+ E L L +GA P + ++F F G R +A PC +E+ +
Sbjct: 285 KARAEDVARLDLSHWDLAFNGAEPVRRETMERFAETFAPAGFRREAFYPCYGLAEATLIV 344
Query: 146 IXXXXXXXXXXXXXVLSMSGLSYGVVRVDAENSLTSLTLQDCGQVMPSCVIVVVKMEGPA 205
L DA T+ TL GQ P +++V E
Sbjct: 345 SGGVKGTPCVQERYDTGSLELGRAKPASDAAEGPTARTLVSSGQGAPDQRLLIVDPETRV 404
Query: 206 YLCKTDEVGEICVLSGATGSGYWGLPGLTNTVFRVRPLDSDGEPIGEEHYVRSXXXXXXX 265
++EVGE+ V + GYW P T F R + +G ++R+
Sbjct: 405 PRA-SNEVGEVWVAGPSVAGGYWDRPEETAHAFGARLANGEGP------FLRTGDLAFLS 457
Query: 266 XXXXXXXXXSRDGLMTVTGRKHNMDDIIATVLAVEPMKFIYRGRIAVFSVRVLRDERICI 325
L+ V GR D+ T A + + G A FSV V +ER+ +
Sbjct: 458 PEGELFITGRLKDLLIVRGRNLYPQDLEMT--AERAHRAVRPGCSAAFSVDVEGEERLVV 515
Query: 326 VAEQRPDCGEEESFQWMSRVLQAVDSIHQVGIYCLALVQPNFLPKTPLGGIHLSECKRRF 385
V+E G + + + + +A+ HQV + + L+Q +PKT G I C+ F
Sbjct: 516 VSEVDVREGFDGAAV-VGALRRALADEHQVHAHTVVLLQARSIPKTSSGKIQRRACRDGF 574
Query: 386 LEGTL 390
L G+L
Sbjct: 575 LAGSL 579
Score = 36.3 bits (80), Expect = 4.5
Identities = 28/124 (22%), Positives = 50/124 (40%), Gaps = 7/124 (5%)
Query: 952 VFVVGALDETIMLRGMRYHPIDIENSVMRCHKKIAE-C-AVFT----WTNLLVVVVELDG 1005
+F+ G L + +++RG +P D+E + R H+ + C A F+ LVVV E+D
Sbjct: 462 LFITGRLKDLLIVRGRNLYPQDLEMTAERAHRAVRPGCSAAFSVDVEGEERLVVVSEVDV 521
Query: 1006 NDS-EAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNSRGEKQRMHLRDGFLSDQIDA 1064
+ + S G+ QR RDGFL+ ++
Sbjct: 522 REGFDGAAVVGALRRALADEHQVHAHTVVLLQARSIPKTSSGKIQRRACRDGFLAGSLEV 581
Query: 1065 IYIA 1068
+ ++
Sbjct: 582 VEVS 585
>UniRef50_A4YZI2 Cluster: Putative fatty-acid--CoA ligase; n=1;
Bradyrhizobium sp. ORS278|Rep: Putative fatty-acid--CoA
ligase - Bradyrhizobium sp. (strain ORS278)
Length = 572
Score = 122 bits (293), Expect = 7e-26
Identities = 111/447 (24%), Positives = 187/447 (41%), Gaps = 17/447 (3%)
Query: 458 ILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIF 517
+L RAQS +D + LN +G LT +L +A + L + GD L+F
Sbjct: 10 LLAARAQSQADDPAYLFLNDRGTEESRLTFGDLQARARDMAARLADHAA--PGDRALLVF 67
Query: 518 PPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLL 577
PPGL+ AF+GCL G + V + P+ L + +I D + L LS+ S L
Sbjct: 68 PPGLEFFVAFFGCLIAGIIAVPMM--MPRRLGARDASGAIIADCA-PRLALSS-SAFALR 123
Query: 578 RSKEASNVLDSKAWPMTLDTDDMPKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSH 637
D W T P R A+ +A+L ++ +T G+ +SH
Sbjct: 124 GDLRERFARDGLTWLEVDLTSSDAGGTAPA--RRIEADDVAFLQYTSGSTSEPKGVAVSH 181
Query: 638 AAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIPPSEVEVNP 697
A + + ++IA S + Y +G L L ++Y G +L+ P+ P
Sbjct: 182 ANLLANSEMIRIALGNSRSSTYVNWVPLYHDMGLILNALQTLYVGSLCVLMAPNAFTQRP 241
Query: 698 ALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVVAEERPRIN 757
WL A+ +Y+ C +LC + + + ++L+C + + AE R +
Sbjct: 242 LNWLRAIGRYRAEVACCPNFGYDLCAARYRAD----QMQDVDLSCWKVALNGAEP-VRAD 296
Query: 758 LTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPSTVYVDLRALRNDRVSLVE 817
+ F++ F+ G + A+ ++G + G P + RAL+ R
Sbjct: 297 TLHRFTQTFAPHGFAAEAIYPAYGMAEATLLISGGRRGAGPLLRELSHRALQTHRAE-AP 355
Query: 818 RGSPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNASGYFTIYGDESD 877
S ++ G+ L G ++ +PE+ + +GEIWV P+ A Y+ E+
Sbjct: 356 STPEDSQVVVGCGRALAGEQIAIVDPESCRRLACDEVGEIWVAGPNVARSYWR--NPEAT 413
Query: 878 YADHFSAQLVTGNTGEVYARTGYLGFL 904
A A + +G + RTG LGFL
Sbjct: 414 VAS-LRATITGDASGVSWLRTGDLGFL 439
Score = 71.7 bits (168), Expect = 1e-10
Identities = 94/398 (23%), Positives = 158/398 (39%), Gaps = 20/398 (5%)
Query: 1 MLAHCRMLSVACNYTEGEHMVCVLDFKRETGL-WHAVLASVLNGMHVIFIPYALMKVSPA 59
+LA+ M+ +A + V + + GL +A+ + + V+ P A + P
Sbjct: 184 LLANSEMIRIALGNSRSSTYVNWVPLYHDMGLILNALQTLYVGSLCVLMAPNAFTQ-RPL 242
Query: 60 SWMHMITKHRASIAIVKS--RDLHWGLLATRDHKEISLSSLRMLLVADGANPWSLSSCDQ 117
+W+ I ++RA +A + DL +++ LS ++ L +GA P + +
Sbjct: 243 NWLRAIGRYRAEVACCPNFGYDLCAARYRADQMQDVDLSCWKVAL--NGAEPVRADTLHR 300
Query: 118 FLSVFQSKGVRGDAICPCACSSESMTVCIXXXXXXXXXXXXXVLSMSGLSYGVVRVDAEN 177
F F G +AI P +E+ T+ I + +S + R +A +
Sbjct: 301 FTQTFAPHGFAAEAIYPAYGMAEA-TLLISGGRRGAGPL---LRELSHRALQTHRAEAPS 356
Query: 178 SLT-SLTLQDCGQVMPSCVIVVVKMEGPAYLCKTDEVGEICVLSGATGSGYWGLPGLTNT 236
+ S + CG+ + I +V E L DEVGEI V YW P T
Sbjct: 357 TPEDSQVVVGCGRALAGEQIAIVDPESCRRLA-CDEVGEIWVAGPNVARSYWRNPEATVA 415
Query: 237 VFRVRPLDSDGEPIGEEHYVRSXXXXXXXXXXXXXXXXSRDGLMTVTGRKHNMDDIIATV 296
R + D + ++R+ L+ + G H DI TV
Sbjct: 416 SLRAT-ITGDASGVS---WLRTGDLGFLDADGELFITGRIKDLLIIRGVNHYPQDIEHTV 471
Query: 297 LAVEPMKFIYRGRIAVFSVRVLR-DERICIVAE-QRPDCGEEESFQWMSRVLQAVDSIHQ 354
A +P G A FSV E + IV E +R + + + S + + V H+
Sbjct: 472 QATDPALRPNCG--AAFSVPDEDGSETLAIVQEVERTERKRIDLAELTSMIRERVTEQHE 529
Query: 355 VGIYCLALVQPNFLPKTPLGGIHLSECKRRFLEGTLHP 392
V +AL++P LPKT G I ++ +L+G L P
Sbjct: 530 VFARHIALIRPGQLPKTTSGKIQRRRARQMWLDGQLPP 567
>UniRef50_Q094Z1 Cluster: Beta-ketoacyl synthase; n=1; Stigmatella
aurantiaca DW4/3-1|Rep: Beta-ketoacyl synthase -
Stigmatella aurantiaca DW4/3-1
Length = 1072
Score = 121 bits (292), Expect = 9e-26
Identities = 113/452 (25%), Positives = 191/452 (42%), Gaps = 25/452 (5%)
Query: 456 SQILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVAL 515
+ ILR RA FT L + + LT AEL ++A I L GR +G V +
Sbjct: 24 ADILRRRAADQGQAPAFTFLGPQPSEDTTLTYAELDQRARAIAAEL--GGRGLSGQRVLV 81
Query: 516 IFPPGLDLICAFYGCLYVGAVPVTIRPP-HPQNLHTTLPTVRMIVDVSKATLVLSNQSVI 574
PPG + +F+GCLY GA+ V + P L + +D A +++ Q
Sbjct: 82 SLPPGPASVASFFGCLYAGAIAVPVPSPLFSPPLSGPGQMATLAMDSGAAAALVAGQ--- 138
Query: 575 KLLRSKEASNV-LDSKAWPMTLDTDDMPKKKLPIMYRAPTAE--MLAYLDFSVSTTGMLA 631
R E + ++ A + L + + P + P + +A+L ++ T G
Sbjct: 139 ---RPAEGQRLTIEGLAGHIDLIAAEAIQGDPPSDWHPPVVDTRAIAFLQYTAGTLGAPK 195
Query: 632 GIKMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIPPS 691
G++++HA + C +++ + + I L L + GLG L +Y+G H +L+PP
Sbjct: 196 GVRVTHANLLDNCEALRRSLGHTFTDKILLWLPTHQGLGLLEGVLQPLYAGVHCVLMPPQ 255
Query: 692 EVEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVVAE 751
P WL A+S + + ELC + +V++ ++L+ R
Sbjct: 256 LFFQRPGRWLEALSTHGATVSGAPNFAYELCVR----TVSEADRAKLDLSRWRV-AFSGT 310
Query: 752 ERPRINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPSTVYVDLRALRND 811
E+ R F++ F G +A +G + + S P+ V + AL
Sbjct: 311 EQIRAETLERFAEHFGPCGFQSKAFRPLYGLAESTFLISSCKSDAGPTVRGVAVDALSQQ 370
Query: 812 RVSLVERGSPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNASGYFTI 871
R++ ER P + + S V+V+ +P T+ D +GEIWV A GY+
Sbjct: 371 RIT--ER--PGAATKLVSSGPAASVQVLIVDPITRAVRSDQEIGEIWVSGLSVADGYWGR 426
Query: 872 YGDESDYADHFSAQLV-TGNTGEVYARTGYLG 902
G + F +L + + G + RTG LG
Sbjct: 427 VGTTEEV---FRGRLTGSASAGRAFLRTGDLG 455
Score = 55.2 bits (127), Expect = 9e-06
Identities = 80/386 (20%), Positives = 152/386 (39%), Gaps = 26/386 (6%)
Query: 1 MLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLASVLNGMHVIFIPYALMKVSPAS 60
+L +C L + +T + ++ L + GL VL + G+H + +P L P
Sbjct: 204 LLDNCEALRRSLGHTFTDKILLWLPTHQGLGLLEGVLQPLYAGVHCVLMPPQLFFQRPGR 263
Query: 61 WMHMITKHRASIAIVKS--RDLHWGLLATRDHKEISLSSLRMLLVADGANPWSLSSCDQF 118
W+ ++ H A+++ + +L ++ D ++ LS R+ G + ++F
Sbjct: 264 WLEALSTHGATVSGAPNFAYELCVRTVSEADRAKLDLSRWRVAF--SGTEQIRAETLERF 321
Query: 119 LSVFQSKGVRGDAICPCACSSESMTVCIXXXXXXXXXXXXXVLSMSGLSYGVVRVDAENS 178
F G + A P +ES T I V ++ LS + E
Sbjct: 322 AEHFGPCGFQSKAFRPLYGLAES-TFLISSCKSDAGPTVRGV-AVDALSQQRI---TERP 376
Query: 179 LTSLTLQDCGQVMPSCVIVVVKMEGPAYLCKTD-EVGEICVLSGATGSGYWGLPGLTNTV 237
+ L G P+ + V+ ++ ++D E+GEI V + GYWG G T V
Sbjct: 377 GAATKLVSSG---PAASVQVLIVDPITRAVRSDQEIGEIWVSGLSVADGYWGRVGTTEEV 433
Query: 238 FRVRPLDSDGEPIGEEHYVRSXXXXXXXXXXXXXXXXSRDGLMTVTGRKHNMDDIIATVL 297
FR R G ++R+ RD ++ G+ + D+ V
Sbjct: 434 FRGR---LTGSASAGRAFLRTGDLGACVGGDLYVTGRLRD-VIIWQGQDLRLQDLEFDVE 489
Query: 298 AVEPMKFIYRGRIAVFSVRVLRDERICIVAE---QRPDCGEEESFQWMSRVLQA----VD 350
+ P + G + + R+E + ++AE P+ +S + + + +A V+
Sbjct: 490 SSHPA--LLPGSCVAVAAKQGRNEELTLIAEVLPSEPELAPADSRKRLQDITEAIHRRVN 547
Query: 351 SIHQVGIYCLALVQPNFLPKTPLGGI 376
H V + + LV+ LP++ G +
Sbjct: 548 LRHGVTPHAIVLVRAYSLPRSSTGRV 573
>UniRef50_Q87WM8 Cluster: Non-ribosomal peptide synthetase,
initiating component; n=1; Pseudomonas syringae pv.
tomato|Rep: Non-ribosomal peptide synthetase, initiating
component - Pseudomonas syringae pv. tomato
Length = 1753
Score = 120 bits (289), Expect = 2e-25
Identities = 113/471 (23%), Positives = 198/471 (42%), Gaps = 31/471 (6%)
Query: 445 DSDAARKYQFISQILRWRAQSTS---DHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLL 501
D A + ++R+RA S + + FT L +VS LT +L +KA + L
Sbjct: 2 DKPTALHFNTFLDVVRYRATHDSVNAERLAFTYLADGESVSDSLTYVQLDQKARSLAAHL 61
Query: 502 LEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDV 561
R GD V L++PP ++ AFY C+Y G + V P TLP + +I
Sbjct: 62 QRHTR--PGDRVLLVYPPCMEYTIAFYACIYAGVIAVPALSPANAK---TLPRLHLIAQD 116
Query: 562 SKATLVLSNQSVI----KLLRSKEASNVLDSKAWPMTLDTDDMPKKKLPIMYRAPTAEML 617
S+ L L+ +V+ +++ N+L W L ++ + A +
Sbjct: 117 SQPALALTMDAVLTGLQRIVTDDNTPNLLTDITW---LSSNLLVDASADWQCPPTVASDI 173
Query: 618 AYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLS 677
+L ++ +TG G+ +SHA + + K + L + G +
Sbjct: 174 VFLQYTSGSTGAPKGVMVSHANLLANVELSKQTYRIREQDVFVSWLPAHHDFGLIGAIIL 233
Query: 678 SIYSGHHSILIPPSEVEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKG 737
+Y H + PP+ + P WL +S Y+ R T +LC + V + + +
Sbjct: 234 PVYMASHCVQFPPAAFVMRPYRWLKLISDYRARITGGPNFAFQLCVQ----RVTEEQKQS 289
Query: 738 INLACVRTCVVVAEERPRINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSP- 796
++L + V A ER R SF + FS GL P A+ ++G ++ + +P
Sbjct: 290 LDLGSLEIAVNGA-ERIRPGTLRSFVEAFSGCGLKPHAMVPAYGMAESVLLVTANTQTPI 348
Query: 797 --EPSTVYVDLRALRNDRVSLVERGSPHSLCLMESGKLLPG-VKVITANPETKGQCGDSH 853
P + AL N +V ER + ++ L+ +G + G +V +P+ +
Sbjct: 349 GQLPRMRTISKSALENGQVR-PERHATDAVELVATGTEITGDHRVGIFHPQHALRLAAQQ 407
Query: 854 LGEIWVQSPHNASGYFTIYGDESDYADHFSAQLVTGNTGEVYARTGYLGFL 904
+GEIW+ P A Y + E++ + F+ + T + RTG LGF+
Sbjct: 408 VGEIWISGPSTARSY---WRQEAE-SQVFNTRAEGDETR--WFRTGDLGFV 452
Score = 57.6 bits (133), Expect = 2e-06
Identities = 84/394 (21%), Positives = 150/394 (38%), Gaps = 14/394 (3%)
Query: 1 MLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLASVLNGMHVIFIPYALMKVSPAS 60
+LA+ + E + V L + GL A++ V H + P A + P
Sbjct: 196 LLANVELSKQTYRIREQDVFVSWLPAHHDFGLIGAIILPVYMASHCVQFPPAAFVMRPYR 255
Query: 61 WMHMITKHRASIAIVKSRDLHWGLLATRDHKEISLSSLRMLLVADGANPWSLSSCDQFLS 120
W+ +I+ +RA I + + + ++ SL + + +GA + F+
Sbjct: 256 WLKLISDYRARITGGPNFAFQLCVQRVTEEQKQSLDLGSLEIAVNGAERIRPGTLRSFVE 315
Query: 121 VFQSKGVRGDAICPCACSSES-MTVCIXXXXXXXXXXXXXVLSMSGLSYGVVRVDAENSL 179
F G++ A+ P +ES + V +S S L G VR + ++
Sbjct: 316 AFSGCGLKPHAMVPAYGMAESVLLVTANTQTPIGQLPRMRTISKSALENGQVRPE-RHAT 374
Query: 180 TSLTLQDCGQVMPSCVIVVVKMEGPAYLCKTDEVGEICVLSGATGSGYWGLPGLTNTVFR 239
++ L G + V + A +VGEI + +T YW + VF
Sbjct: 375 DAVELVATGTEITGDHRVGIFHPQHALRLAAQQVGEIWISGPSTARSYWRQEA-ESQVFN 433
Query: 240 VRPLDSDGEPIGEEHYVRSXXXXXXXXXXXXXXXXSRDGLMTVTGRKHNMDDIIATVLAV 299
R ++G+ E + R+ ++ +M +GR DI TV A+
Sbjct: 434 TR---AEGD---ETRWFRTGDLGFVNDGDLYITGRLKE-VMIFSGRNIYPQDIEITVEAI 486
Query: 300 EPMKFIYRGRIAVFSVRVLRDERICIVAEQRPDCGEEESFQWMSRVLQAVDSIHQV-GIY 358
+P F G A FS+ ++ +V ++ E M R+ + H+V +
Sbjct: 487 DP-AFRANG-CAAFSIENGEVSQL-VVVQELESRQHVEFDSVMPRLRAELADRHEVFDLA 543
Query: 359 CLALVQPNFLPKTPLGGIHLSECKRRFLEGTLHP 392
+ LV+ LP+T G I + C+ F L P
Sbjct: 544 AVLLVKTGTLPRTSSGKIQRARCRDLFEAAELKP 577
>UniRef50_Q2JCL4 Cluster: AMP-dependent synthetase and ligase; n=3;
Frankia|Rep: AMP-dependent synthetase and ligase -
Frankia sp. (strain CcI3)
Length = 578
Score = 120 bits (288), Expect = 3e-25
Identities = 112/459 (24%), Positives = 192/459 (41%), Gaps = 21/459 (4%)
Query: 455 ISQILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVA 514
+ ++L+ RA + ++ A VLT +LH +A + L+ + R GD
Sbjct: 7 LPEVLQNRAARQPARRAYVFVDEHEAEKAVLTYGDLHARALAVAGELIRRCR--PGDRAL 64
Query: 515 LIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVI 574
L+FPPGLD I A++GCLY + V + PP +NL R I+ + + VL+ +++
Sbjct: 65 LLFPPGLDFIVAYFGCLYAQVIAVPVNPPR-RNL--IQDATRSIIKDCEPSAVLTVGAMV 121
Query: 575 KLLRSKEASNVLDSKAW----PMTLDTDDMPKKKLPIMYRAPTAEMLAYLDFSVSTTGML 630
+ +R ++ W + +T++ + R + +A+L ++ +T
Sbjct: 122 EHIR-PVVESIRGPLPWLPVDQVADETNETDQAGTSFRPRPCPPDSVAFLQYTSGSTSDP 180
Query: 631 AGIKMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIPP 690
G+ +SH + + ++ A + + G L +Y G SIL+ P
Sbjct: 181 KGVMVSHRNLAANQEMIRRAFDHDQDSTFVGWAPFFHDQGLIGNILQPLYLGATSILMAP 240
Query: 691 SEVEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVVA 750
P WLSA+S+Y+ + ++C + + ++L+C + A
Sbjct: 241 MTFIRWPLRWLSAISRYRAHTSGGPNFAFDVCV----ARAARGDVPDLDLSCWKVAFNGA 296
Query: 751 EERPRINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPSTVYVDLRALRN 810
E R FS +F+ G +A +G + P + D+ AL +
Sbjct: 297 EP-IRHETLRRFSAIFAPHGFDEKAFYPCYGLAEATLLVTGSRKGRGPRALEADVEALGH 355
Query: 811 DRVSLVERGSPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNASGYFT 870
R G S L+ SG +LP ++ +PET C +GEIWV A GY
Sbjct: 356 RRYVPASGGRGRS--LVGSGLVLPEEELRIVDPETGRPCPADEVGEIWVSGDQVAQGY-- 411
Query: 871 IYGDESDYADHFSAQLVTGNTGEVYARTGYLGFLRRTEI 909
+ A+ F A+ G TG Y RTG LG L E+
Sbjct: 412 -WRRPEATAEVFHAEF-DGETGRAYLRTGDLGLLVDGEV 448
Score = 64.9 bits (151), Expect = 1e-08
Identities = 91/390 (23%), Positives = 152/390 (38%), Gaps = 20/390 (5%)
Query: 1 MLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLASV-LNGMHVIFIPYALMKVSPA 59
+ A+ M+ A ++ + V F + GL +L + L ++ P ++ P
Sbjct: 190 LAANQEMIRRAFDHDQDSTFVGWAPFFHDQGLIGNILQPLYLGATSILMAPMTFIRW-PL 248
Query: 60 SWMHMITKHRASIAIVKSR--DLHWGLLATRDHKEISLSSLRMLLVADGANPWSLSSCDQ 117
W+ I+++RA + + D+ A D ++ LS ++ +GA P + +
Sbjct: 249 RWLSAISRYRAHTSGGPNFAFDVCVARAARGDVPDLDLSCWKVAF--NGAEPIRHETLRR 306
Query: 118 FLSVFQSKGVRGDAICPCACSSESMTVCIXXXXXXXXXXXXXVLSMSGLSYGVVRVDAEN 177
F ++F G A PC +E+ T+ + L + G R +
Sbjct: 307 FSAIFAPHGFDEKAFYPCYGLAEA-TLLVTGSRKGRGPRA---LEADVEALGHRRYVPAS 362
Query: 178 SLTSLTLQDCGQVMPSCVIVVVKMEGPAYLCKTDEVGEICVLSGATGSGYWGLPGLTNTV 237
+L G V+P + +V E C DEVGEI V GYW P T V
Sbjct: 363 GGRGRSLVGSGLVLPEEELRIVDPE-TGRPCPADEVGEIWVSGDQVAQGYWRRPEATAEV 421
Query: 238 FRVRPLDSDGEPIGEEHYVRSXXXXXXXXXXXXXXXXSRDGLMTVTGRKHNMDDIIATVL 297
F + DGE Y+R+ +D L+ + GR + DI TV
Sbjct: 422 FHA---EFDGET--GRAYLRTGDLGLLVDGEVYVVGRLKD-LVIIRGRNYYPHDIELTVQ 475
Query: 298 AVEPMKFIYRGRIAVFSVRVLRDERICIVAEQRPDCG-EEESFQWMSRVLQAVDSIHQVG 356
+ P + G A FSV E++ +V E R + ++ + + AV H +
Sbjct: 476 SAHPA--LRPGGCAAFSVPGADSEKLVVVQEIRDEQRLTADARDVAASIRAAVTREHDLS 533
Query: 357 IYCLALVQPNFLPKTPLGGIHLSECKRRFL 386
+ L L P L KT G I + + R+L
Sbjct: 534 VNDLVLALPGRLQKTSSGKIMRAAARNRYL 563
Score = 37.9 bits (84), Expect = 1.5
Identities = 22/69 (31%), Positives = 34/69 (49%), Gaps = 7/69 (10%)
Query: 926 DSDTDSLASACGSVSILPDSHDTHDAVFVVGALDETIMLRGMRYHPIDIENSVMRCHKKI 985
D +T G + +L D V+VVG L + +++RG Y+P DIE +V H +
Sbjct: 427 DGETGRAYLRTGDLGLLVDGE-----VYVVGRLKDLVIIRGRNYYPHDIELTVQSAHPAL 481
Query: 986 --AECAVFT 992
CA F+
Sbjct: 482 RPGGCAAFS 490
>UniRef50_A3RTM9 Cluster: Putative uncharacterized protein; n=1;
Ralstonia solanacearum UW551|Rep: Putative
uncharacterized protein - Ralstonia solanacearum UW551
Length = 582
Score = 120 bits (288), Expect = 3e-25
Identities = 112/460 (24%), Positives = 187/460 (40%), Gaps = 21/460 (4%)
Query: 452 YQFISQILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGD 511
++ + +L +R + +T L ++ +T E + + + L K N GD
Sbjct: 8 FRHYNDLLDYRTAHQGSQIAYTYLEDGENIAASVTYREFASQVKDVAAEL--KRHANPGD 65
Query: 512 HVALIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQ 571
V L++P G+D + AF+ CLY G + V PP + L IV S A + L+ Q
Sbjct: 66 RVMLLYPSGIDYMVAFFACLYAGLIAVPAFPPRNSKHNARLVA---IVKDSGAKIALTTQ 122
Query: 572 SVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKKLPIMYRAPTAEMLAYLDFSVSTTGMLA 631
++ + A++ + A + T E +A+L ++ +TG
Sbjct: 123 GQLQQMEMGIAASA-ELAALRFICNDAAAQGSGAGCAAADITGETVAFLQYTSGSTGQPK 181
Query: 632 GIKMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIPPS 691
G+ ++HA + R ++ + I L Y +G L + + G H +++ P
Sbjct: 182 GVMVTHANLICNQRMLRAGFATHEGATIVTWLPIYHDMGLIGKMLHAFWLGGHCVVMSPI 241
Query: 692 EVEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVVAE 751
P WL A+S++K + LC ++ + ++L+ T AE
Sbjct: 242 AFLQRPVRWLKAISRFKAHCSGGPNFAYGLCC----DKISAEQKAELDLSSWHTAFNGAE 297
Query: 752 ERPRINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPSTVYVDLRALRND 811
R L FS+ F+A G A+ +G I SP P VY L
Sbjct: 298 PVRRHTL-ERFSEAFAAAGFKREALLPCYGMAETTLIV--SGRSPMPGPVYQHLDPAAFG 354
Query: 812 RVSLVERGSPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNASGYFTI 871
++ G + ++ G L + ANP T C +GEIWV H A GY+
Sbjct: 355 MGRAIKSGQADAYVIVGCGHSLLEQNLRIANPRTLATCRPGEVGEIWVAGQHVAPGYW-- 412
Query: 872 YGDESDY-ADHFSAQLVTGNTGE-VYARTGYLGFLRRTEI 909
++ D A F A L +TGE + RTG LG+L E+
Sbjct: 413 --EKPDVNAATFGAHL--SDTGEGPFLRTGDLGYLDDGEL 448
Score = 70.1 bits (164), Expect = 3e-10
Identities = 89/398 (22%), Positives = 158/398 (39%), Gaps = 28/398 (7%)
Query: 1 MLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLASVLNGMH-VIFIPYALMKVSPA 59
++ + RML EG +V L + GL +L + G H V+ P A ++ P
Sbjct: 190 LICNQRMLRAGFATHEGATIVTWLPIYHDMGLIGKMLHAFWLGGHCVVMSPIAFLQ-RPV 248
Query: 60 SWMHMITKHRASIAIVKSRDLHWGL----LATRDHKEISLSSLRMLLVADGANPWSLSSC 115
W+ I++ +A + + +GL ++ E+ LSS +GA P +
Sbjct: 249 RWLKAISRFKAHCS--GGPNFAYGLCCDKISAEQKAELDLSSWHTAF--NGAEPVRRHTL 304
Query: 116 DQFLSVFQSKGVRGDAICPCACSSESMTVCIXXXXXXXXXXXXXVLSMSGLSYGVVRVDA 175
++F F + G + +A+ PC +E+ + + ++G+ R
Sbjct: 305 ERFSEAFAAAGFKREALLPCYGMAETTLIV----SGRSPMPGPVYQHLDPAAFGMGRAIK 360
Query: 176 ENSLTSLTLQDCGQVMPSCVIVVVKMEGPAYL--CKTDEVGEICVLSGATGSGYWGLPGL 233
+ + CG S + +++ P L C+ EVGEI V GYW P +
Sbjct: 361 SGQADAYVIVGCGH---SLLEQNLRIANPRTLATCRPGEVGEIWVAGQHVAPGYWEKPDV 417
Query: 234 TNTVFRVRPLDSDGEPIGEEHYVRSXXXXXXXXXXXXXXXXSRDGLMTVTGRKHNMDDII 293
F D+ GE ++R+ +D ++ V G DI
Sbjct: 418 NAATFGAHLSDT-----GEGPFLRTGDLGYLDDGELYVSGRLKD-VLIVRGVNKYPQDIE 471
Query: 294 ATVLAVEPMKFIYRGRIAVFSVRVLRDERICIVAE-QRPDCGEEESFQWMSRVLQAVDSI 352
ATV E I +A F + R+ER+ VAE R + + + + + V
Sbjct: 472 ATV--EEADAAIQPAGVAAFMIDDGREERVVAVAEVTRTGLRKADLQAVTADIRRLVLET 529
Query: 353 HQVGIYCLALVQPNFLPKTPLGGIHLSECKRRFLEGTL 390
H+V + + L++P LPKT G + ++ + +L L
Sbjct: 530 HEVLLSDVVLIRPATLPKTSSGKVQRAQARALYLADQL 567
>UniRef50_Q7UYT8 Cluster: Saframycin Mx1 synthetase B; n=2;
Bacteria|Rep: Saframycin Mx1 synthetase B -
Rhodopirellula baltica
Length = 1204
Score = 118 bits (284), Expect = 9e-25
Identities = 124/473 (26%), Positives = 197/473 (41%), Gaps = 43/473 (9%)
Query: 454 FISQILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHV 513
F+S + W Q D FT + +G+ + L+ AEL ++ + L + + GD V
Sbjct: 45 FVSVLRHW-VQVRPDAPAFTFTDGEGS-DQTLSYAELWEEVRGLAGYLQGRCGIRAGDRV 102
Query: 514 ALIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSV 573
L++PPGLD + + GA+ V P +P + +R IV + A LS SV
Sbjct: 103 LLLYPPGLDFVIGLFATHAAGAIAV---PAYPPRRNRKASRIRSIVVDADARWALSTSSV 159
Query: 574 IKLLRSKEASNVLDSKAWPMTLDTDDMPKKKLPIMYRAP--TAEMLAYLDFSVSTTGMLA 631
+ L + N L + L D+P K+ +R P +E L L ++ +TG
Sbjct: 160 VDQL----SGNELHEDLVGVQLLGTDLPTKRDATHWRCPKLRSEALGVLQYTSGSTGSPK 215
Query: 632 GIKMSHAAVTSLCRSMKIACELYPSRHI--ALCLDPYCGLGFALWCLSSIYSGHHSILIP 689
G+ ++ A + + S I P I A L Y +G L ++ G H+IL+
Sbjct: 216 GVMLTQANL--IANSELILHGFEPESTIIGASWLPTYHDMGLVGGVLMPMFVGRHNILMS 273
Query: 690 PSEVEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVV 749
P P+ WL +++++V + +LC + + +G++L+
Sbjct: 274 PMAFLQRPSRWLQTIARHQVTISGGPNFAYQLCV----DKIRDEELEGVDLSSWEIAFNG 329
Query: 750 AEERPRINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPSTVYVDLRALR 809
AE R + ++FSK F G + +G I G SP P D AL
Sbjct: 330 AEP-VRSSTLDAFSKRFEKYGFRHSSHLPCYGMAETTLIVTGGPISPRPVLQQFDGPALD 388
Query: 810 NDRV-------------SLVERGSPHSLC-----LMESGKLLPGVKVITANPETKGQCGD 851
V S E S S L+ G++LPG +V+ +P+T+
Sbjct: 389 EKAVRPAVDVPADLAKQSDDEDDSKTSSARATRELVGCGRVLPGERVLIVDPDTRQTLPS 448
Query: 852 SHLGEIWVQSPHNASGYFTIYGDESDYADHFSAQLVTGNTGEVYARTGYLGFL 904
+GEIWVQSP GY + A F+A +T + RTG LGFL
Sbjct: 449 DAIGEIWVQSPSVGRGY---WQRREQSAKTFAA--MTSEGEGPFLRTGDLGFL 496
Score = 52.8 bits (121), Expect = 5e-05
Identities = 84/378 (22%), Positives = 148/378 (39%), Gaps = 39/378 (10%)
Query: 29 ETGLWHAVLASVLNGMH-VIFIPYALMKVSPASWMHMITKHRASIAIVKSRDLHWGLLAT 87
+ GL VL + G H ++ P A ++ P+ W+ I +H+ +I+ + +
Sbjct: 252 DMGLVGGVLMPMFVGRHNILMSPMAFLQ-RPSRWLQTIARHQVTISGGPNFAYQLCVDKI 310
Query: 88 RDHKEISLSSLRMLLVADGANPWSLSSCDQFLSVFQSKGVRGDAICPCACSSESMTVC-- 145
RD + + + +GA P S+ D F F+ G R + PC +E+ +
Sbjct: 311 RDEELEGVDLSSWEIAFNGAEPVRSSTLDAFSKRFEKYGFRHSSHLPCYGMAETTLIVTG 370
Query: 146 -------IXXXXXXXXXXXXXVLSMSGLSYGVVRV--DAENSLTSLT-----LQDCGQVM 191
+ V + + + D ++S TS L CG+V+
Sbjct: 371 GPISPRPVLQQFDGPALDEKAVRPAVDVPADLAKQSDDEDDSKTSSARATRELVGCGRVL 430
Query: 192 PSCVIVVVKMEGPAYLCKTDEVGEICVLSGATGSGYWGLPGLTNTVFRVRPLDSDGEPIG 251
P +++V + L +D +GEI V S + G GYW + F + G
Sbjct: 431 PGERVLIVDPDTRQTL-PSDAIGEIWVQSPSVGRGYWQRREQSAKTFAAMTSE------G 483
Query: 252 EEHYVRSXXXXXXXXXXXXXXXXSRDGLMTVTGRKHNMDDIIATVLAVEPMKFIYRGRIA 311
E ++R+ +D ++ V G DI ATV + + G +A
Sbjct: 484 EGPFLRTGDLGFLYGGQLYVSGRLKD-MIIVRGVNRYPQDIEATVEHASDV--VQAGSVA 540
Query: 312 VFSVRVLRD------ERICIVAE--QRPDCGEEESFQWMSRVLQAVDSIHQVGIYCLALV 363
F++ D E++ IVAE ++ D ++ Q + R AV H + + LV
Sbjct: 541 AFAMNADSDETETGREKLIIVAETVRKRDLDWDDHLQSIRR---AVTEEHDLPPDAIYLV 597
Query: 364 QPNFLPKTPLGGIHLSEC 381
+ + +PKT G I C
Sbjct: 598 RNSSVPKTSSGKIQRHAC 615
>UniRef50_Q3JS97 Cluster: Unnamed protein product; n=10;
Burkholderia pseudomallei|Rep: Unnamed protein product -
Burkholderia pseudomallei (strain 1710b)
Length = 6274
Score = 118 bits (284), Expect = 9e-25
Identities = 112/444 (25%), Positives = 183/444 (41%), Gaps = 29/444 (6%)
Query: 462 RAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGL 521
RA + D + + L+ G + L+ L + A R+ L G GD V ++ P L
Sbjct: 14 RAAANGDALAYHYLSPHGE-DRALSFGALDRAARRVAARLAASGA--PGDRVLIVCPQSL 70
Query: 522 DLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKE 581
D + AF+GCLY G + V P+N H ++I D ++L + + E
Sbjct: 71 DYVSAFFGCLYGGFIAVPAYA--PRNNHHFARLSKIIEDARPRVVMLCRKQYAAVHAFIE 128
Query: 582 ASNVLDSKAWPMTLDTDDM-PKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAV 640
+ L + + DD+ P P A + +A+L ++ +TG GI +SH +
Sbjct: 129 RNPPLREVELVVVDELDDVEPGGCRP---HAAARDDVAFLQYTSGSTGQAKGIMVSHGNL 185
Query: 641 TSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIPPSEVEVNPALW 700
+ ++ C P L + +G + L +Y G+ + L+ P + NP W
Sbjct: 186 LANEEMIRTTCGNTPDSRAVFWLPLFHDMGL-MTLLQGVYVGYPTYLMAPMDFLANPLRW 244
Query: 701 LSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVVAEERPRINLTN 760
L AVS+ + T +LC + + QL G++L+ V T V E + +
Sbjct: 245 LQAVSRVRATLTVAPNFAWQLCVEKI--PPEQL--DGLDLSSV-TAAVNGSEPISVRTLD 299
Query: 761 SFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPSTVYVDLRALRNDRVSLVERGS 820
F F A G A S+G + + G+S P V + R ++ +R
Sbjct: 300 GFVARFGACGFRREAFRPSYGL-AEATLLVTGSSGHAPDGVIEETMVSSAGRRTVFQR-- 356
Query: 821 PHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNASGYFTIYGDESDYAD 880
+ G+ G +V +T+ D LGEIWV+ PH A GY + + A
Sbjct: 357 ------VGCGRPAAGCEVAIVERDTRAVRRDGELGEIWVKGPHVAQGY---WNNPEQTAQ 407
Query: 881 HFSAQLVTGNTGEVYARTGYLGFL 904
F + T + Y TG LGFL
Sbjct: 408 TFGNR--TADGAGPYLATGDLGFL 429
Score = 43.6 bits (98), Expect = 0.029
Identities = 21/57 (36%), Positives = 35/57 (61%), Gaps = 1/57 (1%)
Query: 490 LHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQ 546
L+++A R+ + LL G V +G++VA++ P +++ A Y L VG V I P +PQ
Sbjct: 5558 LNRQANRLAHYLLSLG-VTSGENVAVMLRPSFEMVVALYAILKVGGAFVPIGPQYPQ 5613
Score = 39.5 bits (88), Expect = 0.48
Identities = 52/190 (27%), Positives = 78/190 (41%), Gaps = 18/190 (9%)
Query: 488 AELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQN 547
A L+ A R+ L G V D VAL PG A L +GA V I P +P
Sbjct: 2335 AVLNATANRLARRLRTLG-VAPRDAVALCMRPGPSFALAALAVLKLGAAYVPIDPRYPD- 2392
Query: 548 LHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWP-MTLDTDDMPKKKLP 606
P IV S A LV++ +A + + W + +P L
Sbjct: 2393 -----PRKLRIVADSGARLVVAEPDAAPA----QAPDAVAPVWWDALAAQAATLPDSDLD 2443
Query: 607 IMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIALCLDPY 666
I AP + LAY+ ++ TTG G+++ H + +LC A L+ + ++
Sbjct: 2444 IE-TAP--DDLAYIVYTSGTTGAPKGVEIPHRGLANLCAWHARAYGLHDAPQ-SIRASQT 2499
Query: 667 CGLGF--ALW 674
G+GF A+W
Sbjct: 2500 AGIGFDAAVW 2509
>UniRef50_A3YGJ3 Cluster: Beta-ketoacyl synthase; n=1; Marinomonas
sp. MED121|Rep: Beta-ketoacyl synthase - Marinomonas sp.
MED121
Length = 714
Score = 118 bits (283), Expect = 1e-24
Identities = 114/468 (24%), Positives = 194/468 (41%), Gaps = 30/468 (6%)
Query: 452 YQFISQILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGD 511
Y + ++L + S D FTLL V++ ++ A+L +A + L + GD
Sbjct: 12 YSNLIELLEHQVSSNGDKTCFTLLANGSDVAETISYAQLSTRARAMAVEL--RALSEPGD 69
Query: 512 HVALIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHT-TLPTVRMIVDVSKATLVLSN 570
L+ P G+D I F+GC+Y G + VT P + L ++ D S A +
Sbjct: 70 RAMLLMPNGIDYIVGFFGCIYAGLIAVTAYAPQQRRRDWGRLTSILKDADASLALCSAEH 129
Query: 571 QSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKKLPIMYRAPTAEMLAYLDFSVSTTGML 630
+K ++ D + + + +M AE +AYL +S +TG
Sbjct: 130 NDQVKAWLAES-----DQACHQFVVGEEAINSAAQWVMPNI-NAETVAYLQYSSGSTGSP 183
Query: 631 AGIKMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIPP 690
G+ + H + + L +I L Y +GF + L+ + +G L+ P
Sbjct: 184 KGVMLGHGNLIQNTALIVQELSLTECGNIVSWLPMYHDMGFVGFVLAPMCAGASVWLLLP 243
Query: 691 SEVEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVVA 750
V P LWL A+S +K + + E C + V++ + + ++L+ R V A
Sbjct: 244 PVVLQAPFLWLKAISDHKAVLSGGPNFIYEHCV----ARVSEEQKQTLDLSHWRFAVNGA 299
Query: 751 EERPRINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPSTVYVDLRALRN 810
E L F++ F+ GLS A+ +G A V ++ AL+
Sbjct: 300 EPIHTATL-EKFNQTFAECGLSKHALKPCYGMAETCLFVTSTAIDQSYRNVQLNKAALQK 358
Query: 811 DRVSLVERGSPHSLCLME-------SGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPH 863
R+ V+ G + L E SG+L + V +PETK D +GEIW++
Sbjct: 359 GRLVRVKEGDLNEQDLFENLVDVPSSGRLNDQMAVSIVDPETKQVLADDRVGEIWIRGAS 418
Query: 864 NASGYFT-------IYGDESDYADHFSAQLVTGNTGEVYARTGYLGFL 904
A GY+ ++ ++ + + +V N G Y RTG LGF+
Sbjct: 419 VAQGYWNKPEVNAEVFNNDVLFYSQTTKDVVDKNGG--YLRTGDLGFI 464
Score = 54.0 bits (124), Expect = 2e-05
Identities = 81/389 (20%), Positives = 156/389 (40%), Gaps = 23/389 (5%)
Query: 15 TEGEHMVCVLDFKRETGLWHAVLASVLNGMHVIFIPYALMKVSPASWMHMITKHRASIAI 74
TE ++V L + G VLA + G V + ++ +P W+ I+ H+A ++
Sbjct: 207 TECGNIVSWLPMYHDMGFVGFVLAPMCAGASVWLLLPPVVLQAPFLWLKAISDHKAVLSG 266
Query: 75 VKSRDLHWGLLATRDHKEISLSSLRMLLVADGANPWSLSSCDQFLSVFQSKGVRGDAICP 134
+ + + ++ +L +GA P ++ ++F F G+ A+ P
Sbjct: 267 GPNFIYEHCVARVSEEQKQTLDLSHWRFAVNGAEPIHTATLEKFNQTFAECGLSKHALKP 326
Query: 135 CACSSESMTVCIXXXXXXXXXXXXXV-LSMSGLSYG-VVRVDA----ENSLTS--LTLQD 186
C +E+ C+ V L+ + L G +VRV E L + +
Sbjct: 327 CYGMAET---CLFVTSTAIDQSYRNVQLNKAALQKGRLVRVKEGDLNEQDLFENLVDVPS 383
Query: 187 CGQVMPSCVIVVVKMEGPAYLCKTDEVGEICVLSGATGSGYWGLPGLTNTVFR--VRPLD 244
G++ + +V E L D VGEI + + GYW P + VF V
Sbjct: 384 SGRLNDQMAVSIVDPETKQVLAD-DRVGEIWIRGASVAQGYWNKPEVNAEVFNNDVLFYS 442
Query: 245 SDGEPIGEEH--YVRSXXXXXXXXXXXXXXXXSRDGLMTVTGRKHNMDDIIATVLAVEPM 302
+ + +++ Y+R+ +++ ++ V GR DI A+V V+
Sbjct: 443 QTTKDVVDKNGGYLRTGDLGFILDGWLYVSGRAKE-VVIVNGRNLYPQDIEASVQVVDKD 501
Query: 303 KFIYRGRIAVFSVRVLRDERICIVAEQRPDCGEEESFQ-WMSRVLQAVDSIHQVGIYCLA 361
+ G AVF D ++ +V E ++++ + + QAV + + + +
Sbjct: 502 LAPHGG--AVFQT---TDNKVVLVQEVTRQGMRNKNYEDIILSIRQAVAEEYDISLSAVV 556
Query: 362 LVQPNFLPKTPLGGIHLSECKRRFLEGTL 390
L++P L KT G I + + + +G L
Sbjct: 557 LIKPVSLAKTTSGKIQRLKNRDLYEQGAL 585
>UniRef50_Q7NJ84 Cluster: Gll1948 protein; n=21; Bacteria|Rep:
Gll1948 protein - Gloeobacter violaceus
Length = 596
Score = 116 bits (280), Expect = 3e-24
Identities = 112/457 (24%), Positives = 193/457 (42%), Gaps = 21/457 (4%)
Query: 455 ISQILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVA 514
+ + RW + ++ + + GAV LT E+ + A I L + G
Sbjct: 21 VEALRRWASVRSARNAYTWEGESAGAVR--LTFFEIDRLARAIAARLQQSNL--RGRRAV 76
Query: 515 LIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVI 574
L++PPGL+ + AF GCLY G V P P+ P ++ I+ + T VL+ +
Sbjct: 77 LLYPPGLEFVAAFMGCLYAGVTAVPAHSPRPRR---PAPKLQAILADAGVTAVLT--TAA 131
Query: 575 KLLRSKEASNVLDSKAWPMTLDTDDMPKKKLPIMYRAP-TAEMLAYLDFSVSTTGMLAGI 633
L RS + + A L TD++ + + LA+L ++ +TG G+
Sbjct: 132 SLARSDQWTTQNPQLAGLQWLATDNLGTDLADTWQECTFSKDSLAFLQYTSGSTGHPKGV 191
Query: 634 KMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIPPSEV 693
++H + R ++ A A L + +G L ++ G +L+ P +
Sbjct: 192 MITHGNLLHNQRMVEGAFGHSDETIFAGWLPLFHDMGLIGNVLQPLHLGIPCVLMSPVDF 251
Query: 694 EVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVVAEER 753
P WL A+++++ + +LC + V+ + +G++L+ R AE
Sbjct: 252 VQKPRRWLEAITRHRATTSGGPNFAYDLCVR----KVSAEQREGLDLSSWRVAFNGAEP- 306
Query: 754 PRINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPSTV-YVDLRALRNDR 812
R + +F+ F+ G +A +G + + G P+ V V AL DR
Sbjct: 307 VRAHTLQAFAAAFAGCGFRAKAFYPCYGL-AEATLFVTGGLFQTPAVVRSVAAAALEQDR 365
Query: 813 VSLVERGSPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNASGYFTIY 872
V P S L+ G+ G +V+ A+P C + +GEIWV P A GY +
Sbjct: 366 VVPAAEDDPGSRLLVGCGRPWLGQEVVIADPTNLTLCPPAQVGEIWVAGPSVARGY---W 422
Query: 873 GDESDYADHFSAQLVTGNTGEVYARTGYLGFLRRTEI 909
++ A F A+L G + RTG LGF+ E+
Sbjct: 423 NRPAETAATFGARLAGTGAGP-FLRTGDLGFIEGGEL 458
Score = 88.6 bits (210), Expect = 8e-16
Identities = 96/393 (24%), Positives = 159/393 (40%), Gaps = 16/393 (4%)
Query: 1 MLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLASVLNGMHVIFIPYALMKVSPAS 60
+L + RM+ A +++ L + GL VL + G+ + + P
Sbjct: 198 LLHNQRMVEGAFGHSDETIFAGWLPLFHDMGLIGNVLQPLHLGIPCVLMSPVDFVQKPRR 257
Query: 61 WMHMITKHRASIAIVKS--RDLHWGLLATRDHKEISLSSLRMLLVADGANPWSLSSCDQF 118
W+ IT+HRA+ + + DL ++ + + LSS R+ +GA P + F
Sbjct: 258 WLEAITRHRATTSGGPNFAYDLCVRKVSAEQREGLDLSSWRVAF--NGAEPVRAHTLQAF 315
Query: 119 LSVFQSKGVRGDAICPCACSSESMTVCIXXXXXXXXXXXXXVLSMSGLSYGVVRVDAENS 178
+ F G R A PC +E+ T+ + V + + L V AE+
Sbjct: 316 AAAFAGCGFRAKAFYPCYGLAEA-TLFVTGGLFQTPAVVRSVAA-AALEQDRVVPAAEDD 373
Query: 179 LTSLTLQDCGQVMPSCVIVVVKMEGPAYLCKTDEVGEICVLSGATGSGYWGLPGLTNTVF 238
S L CG+ +V+ LC +VGEI V + GYW P T F
Sbjct: 374 PGSRLLVGCGRPWLGQEVVIADPTNLT-LCPPAQVGEIWVAGPSVARGYWNRPAETAATF 432
Query: 239 RVRPLDSDGEPIGEEHYVRSXXXXXXXXXXXXXXXXSRDGLMTVTGRKHNMDDIIATVLA 298
R + P ++R+ +D L+ + G H DI A+V
Sbjct: 433 GARLAGTGAGP-----FLRTGDLGFIEGGELFVTGRLKD-LIIIRGANHYPQDIEASVEN 486
Query: 299 VEPMKFIYRGRIAVFSVRVLRDERICIVAEQRPDCGEEESFQW-MSRVLQAVDSIHQVGI 357
+ + G A F+V +ER+ +V E + F+ +S + QAV + H + +
Sbjct: 487 CH--RALRPGCGAAFAVEFDGEERLVVVQELERQLPQALDFEEVLSSIRQAVAARHGLHV 544
Query: 358 YCLALVQPNFLPKTPLGGIHLSECKRRFLEGTL 390
AL++ +PKT G I C+ +FL+GTL
Sbjct: 545 DTAALIKTGSIPKTSSGKIQRRTCRSQFLDGTL 577
Score = 39.5 bits (88), Expect = 0.48
Identities = 25/59 (42%), Positives = 34/59 (57%), Gaps = 6/59 (10%)
Query: 952 VFVVGALDETIMLRGMRYHPIDIENSVMRCHKKI-----AECAV-FTWTNLLVVVVELD 1004
+FV G L + I++RG ++P DIE SV CH+ + A AV F LVVV EL+
Sbjct: 458 LFVTGRLKDLIIIRGANHYPQDIEASVENCHRALRPGCGAAFAVEFDGEERLVVVQELE 516
>UniRef50_Q7UWD6 Cluster: Acyl-CoA synthetase; n=1; Pirellula
sp.|Rep: Acyl-CoA synthetase - Rhodopirellula baltica
Length = 781
Score = 116 bits (279), Expect = 3e-24
Identities = 124/492 (25%), Positives = 198/492 (40%), Gaps = 45/492 (9%)
Query: 451 KYQFISQILRWRAQSTSDHVIFTLL---NAKGAVS-KVLTCAELHKKAERIGNLLLEKGR 506
+++ ++ +L RA D T L + GA + LT AELH++ + N LL
Sbjct: 19 RWKSLAHLLVDRAARHPDRPALTFLPDDSLDGAEEPQTLTYAELHRRVCAVANRLLRDTG 78
Query: 507 VNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATL 566
GD L+FPPGL+ + F C +PV P P L T + D + L
Sbjct: 79 ATAGDRAMLLFPPGLEFMVGFMACEMARLIPVPTSYPKPGRAMPRLDT--SVADCRPSVL 136
Query: 567 VLSNQSV--IKLLRSKEASNVLDSKAWPMTLDTD----DMPKKKLPIMYRAPTAEMLAYL 620
+ +++ I R + L A +++ D D+ + LP+ T LA L
Sbjct: 137 ISDQETIAGIDPHRVSPETAALPKIATDASVEEDLTTIDISEDALPLGEIESTD--LALL 194
Query: 621 DFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPS-------RHIALCLDPYCGLGFAL 673
++ +T G+ +SHA + S S++ A + S L P+ +G
Sbjct: 195 QYTSGSTSDPKGVMVSHANLLSNLESIRHAFGIEWSDDDGDNFERGLFWLPPFHDMGLIG 254
Query: 674 WCLSSIYSGHHSILIPPSEVEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQL 733
L +Y G H+IL+ P P WL A+S YK + +LC V+
Sbjct: 255 GILEPLYVGGHAILMSPRSFLARPMRWLRAISDYKATISGAPNFAYQLCV----DRVDLA 310
Query: 734 KSKGINLACVRTCVVVAEERPRINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGA 793
+++ ++L+ AE + F+ FS G +G +
Sbjct: 311 QAESLDLSGWELAFCGAEP-INADTLQQFTDRFSDAGFRGETFCPCYGLAEATLMAASCR 369
Query: 794 SSPEPSTVYVDL--------RALRN--------DRVSLVERGSPHSLCLMESGKLLPGVK 837
S PS + VD R +R D S+ + S L+ SG +
Sbjct: 370 SGQAPSLLDVDKDELAHGRGRVIRQTVLGKTLPDDASIAKPDPATSRQLVSSGSPAHSMT 429
Query: 838 VITANPETKGQCGDSHLGEIWVQSPHNASGYFTIYGDESDYADHFSAQLVTGNTGEVYAR 897
V+ + ETK + D +GEIW+ P SGY + E+ A+ F A L G+ E + R
Sbjct: 430 VLVVDSETKRERPDGEIGEIWLAGPSVTSGY---WKRETVNAEVFGATLADGDPAEKFLR 486
Query: 898 TGYLGFLRRTEI 909
TG LGF+ E+
Sbjct: 487 TGDLGFIHDGEV 498
Score = 56.8 bits (131), Expect = 3e-06
Identities = 80/378 (21%), Positives = 137/378 (36%), Gaps = 27/378 (7%)
Query: 29 ETGLWHAVLASVLNGMHVIFIPYALMKVSPASWMHMITKHRASIAIVKSRDLHWGLLATR 88
+ GL +L + G H I + P W+ I+ ++A+I+ + + + L R
Sbjct: 249 DMGLIGGILEPLYVGGHAILMSPRSFLARPMRWLRAISDYKATIS--GAPNFAYQLCVDR 306
Query: 89 -DHKEI-SLSSLRMLLVADGANPWSLSSCDQFLSVFQSKGVRGDAICPC----------- 135
D + SL L GA P + + QF F G RG+ CPC
Sbjct: 307 VDLAQAESLDLSGWELAFCGAEPINADTLQQFTDRFSDAGFRGETFCPCYGLAEATLMAA 366
Query: 136 ACSSESMTVCIXXXXXXXXXXXXXVLSMSGLSYGV---VRVDAENSLTSLTLQDCGQVMP 192
+C S + V+ + L + + + TS L G
Sbjct: 367 SCRSGQAPSLLDVDKDELAHGRGRVIRQTVLGKTLPDDASIAKPDPATSRQLVSSGSPAH 426
Query: 193 SCVIVVVKMEGPAYLCKTDEVGEICVLSGATGSGYWGLPGLTNTVFRVRPLDSDGEPIGE 252
S ++VV E E+GEI + + SGYW + VF +DG+P
Sbjct: 427 SMTVLVVDSETKRER-PDGEIGEIWLAGPSVTSGYWKRETVNAEVFGATL--ADGDPA-- 481
Query: 253 EHYVRSXXXXXXXXXXXXXXXXSRDGLMTVTGRKHNMDDIIATVLAVEPMKFIYRGRIAV 312
E ++R+ S+D ++ + GR DI ATV + + +A
Sbjct: 482 EKFLRTGDLGFIHDGEVYVTGRSKD-VVILRGRNLFPQDIEATVKGLLQANVLQCAAVAT 540
Query: 313 FSVRVLRDERICIVAEQRPDCGEEESFQWMSRVLQAVDSIHQVGIYCLALVQPNFLPKTP 372
+ + + AE EE + + +A+ H+V + + +P +P T
Sbjct: 541 TG---RTGDALTVAAEVSRHVDSEELPDIVRHIRRAIIDDHEVDARQVLITRPGGIPLTT 597
Query: 373 LGGIHLSECKRRFLEGTL 390
G + +C+ G L
Sbjct: 598 SGKVQRQQCRAMIEAGEL 615
>UniRef50_A3ZQ92 Cluster: Saframycin Mx1 synthetase B; n=1;
Blastopirellula marina DSM 3645|Rep: Saframycin Mx1
synthetase B - Blastopirellula marina DSM 3645
Length = 1124
Score = 116 bits (279), Expect = 3e-24
Identities = 129/532 (24%), Positives = 208/532 (39%), Gaps = 23/532 (4%)
Query: 459 LRWRAQSTSDHVIFTLLNAKGAVSKV-LTCAELHKKAERIGNLLLEKGRVNTGDHVALIF 517
LR+RA+ V + L G K+ +T A+L A + + G+ L+F
Sbjct: 20 LRYRAEHQGPQVAYAYL-VDGEDEKLEMTYAQLDLAARALAARMQALNM--QGERALLLF 76
Query: 518 PPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVI-KL 576
PG++ I AFY CLY GAV V P +P + + ++ I D ++A + L+ V+ ++
Sbjct: 77 APGMEFITAFYACLYAGAVAV---PAYPPRRNRNMVRIQAIADDAQAKIALTTSDVLDRV 133
Query: 577 LRSKEASNVLDSKAWPMTLDTDDMPKKKLPIMYRAPTAE--MLAYLDFSVSTTGMLAGIK 634
+ + L W T D K +R P + LA+L ++ +TG G+
Sbjct: 134 TPMLDETPHLKKIHWLAT----DSEKLVEADQWRMPDIDEKTLAFLQYTSGSTGTPKGVM 189
Query: 635 MSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIPPSEVE 694
+SH+ + + A E S L Y +G L + G +IL+ P
Sbjct: 190 LSHSNMMHNSALISYAFEHTRSMRAVFWLPMYHDMGLIGGVLQPMQIGQPTILMSPMAFL 249
Query: 695 VNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVVAEERP 754
P WL A+++ + + ELC + S + K K ++L+ AE
Sbjct: 250 QQPFRWLRAITKSQATVSGGPNFAYELCVNKITS---EQKDK-LDLSSWELAFNGAEPIK 305
Query: 755 RINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPSTVYVDLRALRNDRVS 814
L + F++ F G A +G I G P VD L V
Sbjct: 306 PETL-DRFTEAFEPCGFRREAFYPCYGMAEATLIISGGLKKSPPVIRTVDGDVLDQGLVV 364
Query: 815 LVERGSPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNASGYFTIYGD 874
+ + ++ G LP +++ +PET Q + +GEIW+ P A GY + +
Sbjct: 365 DADPDEAGARPVVGCGNCLPDQEILIVDPETMLQQPFNKVGEIWIAGPSIAKGY---WRN 421
Query: 875 ESDYADHFSAQLVTGNTGEVYARTGYLGFLRRTEIXXXXXXXXXXXXMLPRDSDTDSLAS 934
E D F A L N G Y RTG LGF++ E+ D A+
Sbjct: 422 EEDTERCFRAHLADTNAGP-YLRTGDLGFMQDGELFVTGRLKDLIIVRGVNRYPQDIEAT 480
Query: 935 ACGSVSILPDSHDTHDAVFVVGALDETIMLRGMRYHPIDIENSVMRCHKKIA 986
C S +L S + + G I+ R D + K++A
Sbjct: 481 VCASHELLETSTAAAFSAEIAGKDRLVIVAEAPRLRQKDYGQIISAIRKEVA 532
Score = 93.5 bits (222), Expect = 3e-17
Identities = 100/394 (25%), Positives = 167/394 (42%), Gaps = 20/394 (5%)
Query: 1 MLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLASVLNGMHVIFI-PYALMKVSPA 59
M+ + ++S A +T V L + GL VL + G I + P A ++ P
Sbjct: 195 MMHNSALISYAFEHTRSMRAVFWLPMYHDMGLIGGVLQPMQIGQPTILMSPMAFLQ-QPF 253
Query: 60 SWMHMITKHRASIAIVKS--RDLHWGLLATRDHKEISLSSLRMLLVADGANPWSLSSCDQ 117
W+ ITK +A+++ + +L + + ++ LSS L +GA P + D+
Sbjct: 254 RWLRAITKSQATVSGGPNFAYELCVNKITSEQKDKLDLSSWE--LAFNGAEPIKPETLDR 311
Query: 118 FLSVFQSKGVRGDAICPCACSSESMTVCIXXXXXXXXXXXXXVLSMSGLSYGVVRVDAE- 176
F F+ G R +A PC +E+ T+ I V L G+V VDA+
Sbjct: 312 FTEAFEPCGFRREAFYPCYGMAEA-TLIISGGLKKSPPVIRTV-DGDVLDQGLV-VDADP 368
Query: 177 NSLTSLTLQDCGQVMPSCVIVVVKMEGPAYLCKTDEVGEICVLSGATGSGYWGLPGLTNT 236
+ + + CG +P I++V E ++VGEI + + GYW T
Sbjct: 369 DEAGARPVVGCGNCLPDQEILIVDPETMLQQ-PFNKVGEIWIAGPSIAKGYWRNEEDTER 427
Query: 237 VFRVRPLDSDGEPIGEEHYVRSXXXXXXXXXXXXXXXXSRDGLMTVTGRKHNMDDIIATV 296
FR D++ P Y+R+ +D L+ V G DI ATV
Sbjct: 428 CFRAHLADTNAGP-----YLRTGDLGFMQDGELFVTGRLKD-LIIVRGVNRYPQDIEATV 481
Query: 297 LAVEPMKFIYRGRIAVFSVRVLRDERICIVAEQRPDCGEEESFQWMSRVLQAVDSIHQVG 356
A + + A FS + +R+ IVAE P +++ Q +S + + V H++
Sbjct: 482 CASHEL--LETSTAAAFSAEIAGKDRLVIVAEA-PRLRQKDYGQIISAIRKEVALEHEMA 538
Query: 357 IYCLALVQPNFLPKTPLGGIHLSECKRRFLEGTL 390
+ +AL++ +PKT G I C+ FL+ L
Sbjct: 539 VDGVALIRRGSIPKTSSGKIQRHACRNHFLQNVL 572
>UniRef50_Q73UT2 Cluster: FadD29; n=2; Mycobacterium avium|Rep:
FadD29 - Mycobacterium paratuberculosis
Length = 1115
Score = 115 bits (276), Expect = 8e-24
Identities = 109/476 (22%), Positives = 198/476 (41%), Gaps = 37/476 (7%)
Query: 447 DAARKYQFISQILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGR 506
D++ I + W Q + +F ++ G + T ++ + L +
Sbjct: 29 DSSTMETLIDYLHLWE-QRRPEQTLFRFVDVDGRELEHYTYRSFAERTRELAAYLSTEAG 87
Query: 507 VNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATL 566
+ GD L++PPGL+++ A Y C +G + V + PP P + + L + I +A
Sbjct: 88 LRAGDCALLVYPPGLEMVAALYACARIGVIAVPVSPPLPMSFESGLAKLGFIARDCQARA 147
Query: 567 VLSNQSV---IKLLRSKEASNVLDSKA------WPMTLDTDDMPKKKLPIMYRAPTAEML 617
VLS + ++L + S A W T + +P T +
Sbjct: 148 VLSTKQFEYDFRMLLGQRHGGQPWSDAGLPELPWFATDGAQEFGGAPVP-----DTPGDV 202
Query: 618 AYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLS 677
+L ++ +T G+ +SH V + + E+ S L + +G +
Sbjct: 203 LFLQYTSGSTSDPKGVIVSHENVIANVSAFTGGSEVLVS-----WLPQHHDMGLISAYMF 257
Query: 678 SIYSGHHSILIPPSEVEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKG 737
+ G + + P + P+ WL +S + T +E C + V + G
Sbjct: 258 ILLQGGTTHAMSPLDFLARPSAWLRLISDVRATHTPVPNFALEYCLRE--DKVPAAELAG 315
Query: 738 INLACVRTCVVVAEERPRINLTNSFSKLFSALGLSPRAVSTSFG-CRVNIAICLQGASSP 796
I+L+ + C+VV E R N + F + F+ GL P A++ ++G + + ++G
Sbjct: 316 IDLSSLE-CIVVGAEPLRANTFHQFRERFAPYGLRPEALTGAYGMAESTLIVSIRGRQ-- 372
Query: 797 EPSTVYVDLRALRNDRVSLVERGSPHS---LCLMESGKLLPGVKVITANPETKGQCGDSH 853
T+ V+ R L + V+ VE+ P + + L+ GK L V +P+T+ G+
Sbjct: 373 ---TLTVNKRGLEKN-VARVEKALPENSNQVPLVSCGKPLEETVVRVVDPQTRQALGEGR 428
Query: 854 LGEIWVQSPHNASGYFTIYGDESDYADHFSAQLVTGNTGEVYARTGYLGFLRRTEI 909
+GE+W+ P GY + A+ F A+L G+ Y RTG LGFL E+
Sbjct: 429 VGEVWLAGPSKGRGY---WNRPQLTAEMFEARL-AGDDEHSYLRTGDLGFLYEGEL 480
Score = 75.8 bits (178), Expect = 6e-12
Identities = 97/398 (24%), Positives = 163/398 (40%), Gaps = 30/398 (7%)
Query: 1 MLAHCRMLSVACNYTEG-EHMVCVLDFKRETGLWHAVLASVLNGMHVIFIPYALMKVSPA 59
+++H +++ +T G E +V L + GL A + +L G + P+
Sbjct: 219 IVSHENVIANVSAFTGGSEVLVSWLPQHHDMGLISAYMFILLQGGTTHAMSPLDFLARPS 278
Query: 60 SWMHMITKHRASIAIVKSRDLHWGL----LATRDHKEISLSSLRMLLVADGANPWSLSSC 115
+W+ +I+ RA+ V + L + L + + I LSSL ++V GA P ++
Sbjct: 279 AWLRLISDVRATHTPVPNFALEYCLREDKVPAAELAGIDLSSLECIVV--GAEPLRANTF 336
Query: 116 DQFLSVFQSKGVRGDAICPCACSSESMTVCIXXXXXXXXXXXXXVLSMSGLSYGVVRVDA 175
QF F G+R +A+ +ES + ++ GL V RV+
Sbjct: 337 HQFRERFAPYGLRPEALTGAYGMAESTLIV------SIRGRQTLTVNKRGLEKNVARVEK 390
Query: 176 ---ENSLTSLTLQDCGQVMPSCVIVVVKMEGPAYLCKTDEVGEICVLSGATGSGYWGLPG 232
ENS + L CG+ + V+ VV + L + VGE+ + + G GYW P
Sbjct: 391 ALPENS-NQVPLVSCGKPLEETVVRVVDPQTRQALGE-GRVGEVWLAGPSKGRGYWNRPQ 448
Query: 233 LTNTVFRVRPLDSDGEPIGEEHYVRSXXXXXXXXXXXXXXXXSRDGLMTVTGRKHNMDDI 292
LT +F R D E Y+R+ S+D L+ V G DI
Sbjct: 449 LTAEMFEARLAGDD-----EHSYLRTGDLGFLYEGELFVCGRSKD-LIIVRGVNCYPSDI 502
Query: 293 IATVLAVEPMKFIYRGRIAVFSVRVLRDERICIVAEQRPDCGEEESFQWMSRVLQAVDSI 352
A V K + G +A SV E + +VAE R +E + + +A+
Sbjct: 503 EAVV--ERSAKQVRGGCVAALSVEQDDQEALVVVAEVR----DEHNLPDARALARAIRRH 556
Query: 353 HQVGIYCLALVQPNFLPKTPLGGIHLSECKRRFLEGTL 390
+ + + P +PKT G I + ++ +L+G L
Sbjct: 557 CHIDPHTIVFAPPRSIPKTTSGKIRRASTRQLWLDGAL 594
>UniRef50_Q5C1Y4 Cluster: SJCHGC08625 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC08625 protein - Schistosoma
japonicum (Blood fluke)
Length = 198
Score = 114 bits (274), Expect = 1e-23
Identities = 54/121 (44%), Positives = 79/121 (65%), Gaps = 5/121 (4%)
Query: 428 QGNRLASAQGRDMGYTDDSDAA-----RKYQFISQILRWRAQSTSDHVIFTLLNAKGAVS 482
QG RLA A+GR +G + S+ ++ + +IL RA T D+ +FT+ NAKG +
Sbjct: 1 QGVRLAEARGRPLGTSPSSNTTSGSSDNGFEMLIEILIHRANHTPDNRLFTVYNAKGQEA 60
Query: 483 KVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRP 542
LTC++L ++AER+ L EKG+ G VAL++PPG +L+CAFY CL +GA+PV +RP
Sbjct: 61 STLTCSQLLRRAERLAVQLKEKGKAQVGTIVALLYPPGTELVCAFYACLLIGAIPVPVRP 120
Query: 543 P 543
P
Sbjct: 121 P 121
>UniRef50_Q1I2J3 Cluster: Putative polyketide synthase; putative
acyl-CoA ligase; n=1; Pseudomonas entomophila L48|Rep:
Putative polyketide synthase; putative acyl-CoA ligase -
Pseudomonas entomophila (strain L48)
Length = 567
Score = 112 bits (270), Expect = 4e-23
Identities = 121/466 (25%), Positives = 198/466 (42%), Gaps = 34/466 (7%)
Query: 449 ARKYQFISQILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVN 508
AR + I R A + +D F + + ++LT EL + + L +
Sbjct: 9 ARAHCNIVDSCRLHASAHADKAAFVFITRQ--TEEILTFGELDAFSRSLALYLCTQNL-- 64
Query: 509 TGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVL 568
G ++ LI+P GL+ I AF CLY GAVPV + P + L + I+D ++ VL
Sbjct: 65 QGRNILLIYPSGLEFIKAFVACLYAGAVPVPVNTPTQPH---ALDRFKKIIDDARIEYVL 121
Query: 569 SNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKKLPIMYRAPTAEMLAYLDFSVSTTG 628
S+ +++ D L TD+ ++ +P ++ A++ ++ +TG
Sbjct: 122 SSSGLMQRFD-------FDVFGELGKLATDEFVAEQTEWSPDSPHSQATAFIQYTSGSTG 174
Query: 629 MLAGIKMSHAAVTSLCRSMKIACELYPSRHI--ALCLDPYCGLGFALWCLSSIYSGHHSI 686
G +SHA + + I HI L + +G L +Y G I
Sbjct: 175 DPKGAVISHANLVN--NLEMIQSGFANDEHIVGVNWLPLFHDMGLVGNVLQPLYLGITCI 232
Query: 687 LIPPSEVEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSK---GINLACV 743
+ P E P WL A+S Y R T S G T G + ++K + G++L+
Sbjct: 233 HMSPLEFVQKPVRWLRAISDY--RGT-TSGGP----TFGFAHCLARIKDEECVGLDLSSW 285
Query: 744 RTCVVVAEERPRINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPSTVYV 803
R AE R + ++F+K FS G +P + +G I + + +
Sbjct: 286 RIAYCGAEP-VRHEVLDAFAKRFSRYGFAPSSFYPCYGMAETTLIVTGPTAGAGLRVLEL 344
Query: 804 DLRALRNDRVSLVERGSPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPH 863
D +L+ +P L L+ +G+ + G +V +PET + D H+GE+WV S
Sbjct: 345 DRNSLQLGLAVAARPDAPGDL-LVSNGRPINGSRVAIVDPETGARKQDMHIGEVWVASSS 403
Query: 864 NASGYFTIYGDESDYADHFSAQLVTGNTGEVYARTGYLGFLRRTEI 909
A GYF + S + F A T V+ RTG LGFL+ E+
Sbjct: 404 VAQGYF---DNPSATRERFGAYFET-EPEVVFYRTGDLGFLKDEEL 445
Score = 51.2 bits (117), Expect = 1e-04
Identities = 82/385 (21%), Positives = 134/385 (34%), Gaps = 17/385 (4%)
Query: 10 VACNYTEGEHMVCV--LDFKRETGLWHAVLASVLNGMHVIFIPYALMKVSPASWMHMITK 67
+ + EH+V V L + GL VL + G+ I + P W+ I+
Sbjct: 193 IQSGFANDEHIVGVNWLPLFHDMGLVGNVLQPLYLGITCIHMSPLEFVQKPVRWLRAISD 252
Query: 68 HRASIAIVKSRDLHWGLLATRDHKEISLSSLRMLLVADGANPWSLSSCDQFLSVFQSKGV 127
+R + + + L +D + + L + GA P D F F G
Sbjct: 253 YRGTTSGGPTFGFAHCLARIKDEECVGLDLSSWRIAYCGAEPVRHEVLDAFAKRFSRYGF 312
Query: 128 RGDAICPCACSSESMTVCIXXXXXXXXXXXXXVLSMSGLSYGVVRVDAENSLTSLTLQDC 187
+ PC +E T I L + L G+ V A L
Sbjct: 313 APSSFYPCYGMAE--TTLIVTGPTAGAGLRVLELDRNSLQLGLA-VAARPDAPGDLLVSN 369
Query: 188 GQVMPSCVIVVVKMEGPAYLCKTD-EVGEICVLSGATGSGYWGLPGLTNTVFRVRPLDSD 246
G+ + + +V E A K D +GE+ V S + GY+ P T F +
Sbjct: 370 GRPINGSRVAIVDPETGAR--KQDMHIGEVWVASSSVAQGYFDNPSATRERFGAY---FE 424
Query: 247 GEPIGEEHYVRSXXXXXXXXXXXXXXXXSRDGLMTVTGRKHNMDDIIATVLAVEPMKFIY 306
EP E + R+ +D L+ + GR + DI T P +
Sbjct: 425 TEP--EVVFYRTGDLGFLKDEELYITGRLKD-LIVIRGRNYYPQDIEQTAFLATP--GLR 479
Query: 307 RGRIAVFSVRVLRDERICIVAE-QRPDCGEEESFQWMSRVLQAVDSIHQVGIYCLALVQP 365
FS R E + +V E ++ + Q + + Q + H + + L++P
Sbjct: 480 ENCGVAFSQRAGEQEGLVLVHEVEKGELDPHTREQMVCAIRQRIIEQHGIAPDAVMLIKP 539
Query: 366 NFLPKTPLGGIHLSECKRRFLEGTL 390
+ KT G + +E RF G L
Sbjct: 540 KGVAKTSSGKLRRAETAARFERGEL 564
>UniRef50_A5B1G8 Cluster: Putative uncharacterized protein; n=2;
cellular organisms|Rep: Putative uncharacterized protein
- Vitis vinifera (Grape)
Length = 2246
Score = 112 bits (270), Expect = 4e-23
Identities = 125/454 (27%), Positives = 184/454 (40%), Gaps = 48/454 (10%)
Query: 471 IFTLLNAKGAVSKVLTCAELHKKAERIG-NLLL-EKGRVNTGDHVALIFPPGLDLICAFY 528
++T +N +G V T ELH A I NLLL +K GD V L++ PGLD I AF+
Sbjct: 513 LYTWINEEGVVVSQRTYRELHANASCIAHNLLLNQKPLFKPGDRVLLVYIPGLDFIDAFF 572
Query: 529 GCLYVGAVPVTIRPPHP-QNLHTTLPTVRMIVDVSKATLVLSN--------QSVIKLLRS 579
GCL +PV + PP P Q L + I A +LS +K L S
Sbjct: 573 GCLRAKLLPVPVLPPDPLQRGGQALLKIENIAKSCNALAILSTIRYHAGVCAGSVKSLIS 632
Query: 580 KEASNVLDSKAWPMT--LDTDDMPKKKLPIMYR------APTAEMLAYLDFSVSTTGMLA 631
N +S WP L TD K ++ P + L +L F+ +TG
Sbjct: 633 FTGKNGKNSARWPNLPWLHTDSWIKYSRNLLQEDIADQSEPQPDDLCFLQFTSGSTGDAK 692
Query: 632 GIKMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIPPS 691
G+ ++H + + M+ + + L Y +G S++ SG ++L P
Sbjct: 693 GVMITHGGLIHNVKLMRRRYKSTSKTVLVSWLPQYHDMGLIGGLFSALVSGGSAVLFSPM 752
Query: 692 EVEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVVAE 751
NP LWL +S+++ + EL + L S + + + NL+ + ++VA
Sbjct: 753 SFIKNPLLWLQTMSKFQATHSAGPNFAFELVVRRLESGKDTVHN--YNLSSM-IFLMVAA 809
Query: 752 ERPRINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAI--CLQGASSPEPSTVYVDLRALR 809
E R N F KL S GL ++ +G N C G P + VD +
Sbjct: 810 EPVRQNTLKRFVKLTSPFGLCEEVLAPGYGLAENCVFVSCAYGEGKP----ILVDWQ--- 862
Query: 810 NDRVSLVERGSPHSLCLMESGKLLPGVKVITANPET-KGQCGDSHLGEIWVQSPHNASGY 868
ER +C V + +PET + Q GEIW+ SP GY
Sbjct: 863 -------ER-----VCCGYVDTENADVDIRVVDPETGEEQEEVGKEGEIWISSPSAGVGY 910
Query: 869 FTIYGDESDYADHFSAQLVTGNTGEVYARTGYLG 902
+G E F +L + G Y RTG LG
Sbjct: 911 ---WGREELSGKTFRNEL-QNHPGRRYTRTGDLG 940
>UniRef50_Q2T6Q9 Cluster: AMP-binding domain protein; n=1;
Burkholderia thailandensis E264|Rep: AMP-binding domain
protein - Burkholderia thailandensis (strain E264 / ATCC
700388 / DSM 13276 /CIP 106301)
Length = 1035
Score = 112 bits (269), Expect = 6e-23
Identities = 117/461 (25%), Positives = 204/461 (44%), Gaps = 27/461 (5%)
Query: 418 PASVIVGNLVQGNRLASAQGRDMGYTDDSDAAR---KYQFISQILRWRAQSTSDHVIFTL 474
PA V+ + +A + G +DAA + + +L W A+ D V L
Sbjct: 168 PADVVRALAAAHAQPQAAPEGEAGPAPPADAAAWPVEADTLIDVLNWHAERHPDRVHLRL 227
Query: 475 LNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVG 534
L G V+ L ELH++A + L E+G ++ GD VAL+ P GLD +F L+ G
Sbjct: 228 LE-DGLVATPLAYGELHRRASDLAGGLRERG-IDPGDTVALMLPTGLDYFVSFTAVLFCG 285
Query: 535 AVPVTIRPP-HPQNLHTTLPTVRMIVDVSKA-TLVLSNQSVIKLLRSKEASNVLDSKAWP 592
A+PV I PP +P L + I++ ++ L+ Q+V K + L P
Sbjct: 286 AIPVPIYPPANPAQLEEHVERHTPILENARIKALIAFRQAVSVAQLLKLRVSTLQHVFTP 345
Query: 593 MTLDTDDMPKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACE 652
L + +++LP +RA ++ +A L ++ +TG G+ +SHA + + R+M
Sbjct: 346 EQL----VGRERLP-PFRAAASD-IALLQYTSGSTGTPKGVVLSHANLLANIRAMGDRMH 399
Query: 653 LYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIPPSEVEVNPALWLSAVSQYKVRDT 712
+Y + + L Y +G L+ +Y G ++++ P PALWL A+S+Y T
Sbjct: 400 VYATDVLVSWLPLYHDMGLIGAWLAPLYFGIPAVVMSPVAFLARPALWLRAISRYHGTIT 459
Query: 713 FCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVVAEERPRINLTNSFSKLFSALGLS 772
E C + L + L+ +L+ +R AE + +F+ F+A G
Sbjct: 460 AAPNFAYERCARHLAA----LEPTEFDLSSLRFAFCGAEP-VNADTLRAFAARFAACGFD 514
Query: 773 PRAVSTSFGCRVNIAICLQGASSPEPST-VYVD--LRALRNDRVSLVER-GSPHSLCLME 828
RA++ +G N G + P P+ ++VD RA N V G ++L +
Sbjct: 515 ARALTPVYGLAENTL----GLTFPPPARGLHVDRIARAPLNASGQAVPAPGDANALDVPG 570
Query: 829 SGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNASGYF 869
G + G ++ + + + + +G I + GY+
Sbjct: 571 CGYPIDGTELRIVGDDER-ELAERRVGRIEFRGTSATRGYY 610
>UniRef50_Q62C92 Cluster: AMP-binding domain protein; n=17;
Bacteria|Rep: AMP-binding domain protein - Burkholderia
mallei (Pseudomonas mallei)
Length = 599
Score = 111 bits (267), Expect = 1e-22
Identities = 100/400 (25%), Positives = 170/400 (42%), Gaps = 17/400 (4%)
Query: 513 VALIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKA-TLVLSNQ 571
V L++P GL + AF GCLY GA+ V + P P + + T R++ D A L +
Sbjct: 64 VLLVYPEGLAFVAAFLGCLYAGAIAVPV--PVPADARSVERTRRIVRDAGIALALTPTAA 121
Query: 572 SVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKKLPIMYRAPT--AEMLAYLDFSVSTTGM 629
L A S + + D + + P A +A+L ++ +TG
Sbjct: 122 DAHALANCLAAPGDAVSTVGALRCEATDALEALDASAWSRPALDASAIAFLQYTSGSTGE 181
Query: 630 LAGIKMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIP 689
G+ +SH + ++ + L + +G L +Y G + +
Sbjct: 182 PKGVVVSHRNLLHNEAQIQRVVASDADSVVTGWLPHFHDMGLIGMLLHPLYVGCDCVFMA 241
Query: 690 PSEVEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVV 749
PS P WL A + Y T +LC + +V + + G++L+ ++ +
Sbjct: 242 PSTFLRRPVRWLEAATHYAATITVAPNFAYDLCAR----AVKREQLGGLDLSALKVALNG 297
Query: 750 AEERPRINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPSTVYVDLRALR 809
AE R +FS F+ +G RA S +G + G + P + +D RAL
Sbjct: 298 AEP-VRAKTIEAFSARFAPVGFDARAFSPCYGMAEVTLLASAGRPAAAPVLLDIDARALE 356
Query: 810 NDRVSLVERGSPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNASGYF 869
SL + G+ +L ++ SG+ + + + +P+T D +GEIW++ A GY+
Sbjct: 357 RHEASLAKPGA-EALRVVGSGRAV-DLDLRIVDPQTHAVAADGRIGEIWLRGDSVAQGYW 414
Query: 870 TIYGDESDYADHFSAQLVTGNTGEVYARTGYLGFLRRTEI 909
D S+ A F A+ G+ Y RTG LGF+R E+
Sbjct: 415 R-RPDASEAA--FRARTAAGD--GPYLRTGDLGFVRDGEL 449
>UniRef50_A4XWA9 Cluster: Amino acid adenylation domain; n=1;
Pseudomonas mendocina ymp|Rep: Amino acid adenylation
domain - Pseudomonas mendocina ymp
Length = 3231
Score = 111 bits (267), Expect = 1e-22
Identities = 114/460 (24%), Positives = 194/460 (42%), Gaps = 34/460 (7%)
Query: 453 QFISQILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDH 512
Q + IL + A+ V + A + T AEL ++A + LL G G+
Sbjct: 19 QHFADILDYHAERVPGRVAIRHIVADQGEPLLTTYAELREQALAVAGLLQRLG-CQAGER 77
Query: 513 VALIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQS 572
L+ P G D AF+GCLY G + V PP N + + I+ ++ +VL+ +
Sbjct: 78 CVLMLPSGADYAAAFFGCLYAGVIAVPAFPPE-NNRQMHIERLTGILLDAQPMVVLAPRE 136
Query: 573 VIKLLRSKEASNVLDSKAWPMTLDTDDMPKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAG 632
VI+ + + +L +A + ++ D + + R +++ LA+L ++ +T G
Sbjct: 137 VIRRCQ-VDLQPLLAPEAQMIAIEDVD-ARDRAGYQPRLISSDTLAFLQYTSGSTRAPKG 194
Query: 633 IKMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIPPSE 692
+ +SHA + + RSM L Y +G L I G L+ P+
Sbjct: 195 VMVSHANLLANERSMSRGFSASREESWVSWLPLYHDMGLMAGLLLPILHGGTLTLMAPNF 254
Query: 693 VEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVVAEE 752
PA WL A+SQY TF G + + V Q + ++L+ R E
Sbjct: 255 FLARPARWLQAISQY--GGTFS--GGPDFAYRLCAERVPQSSLEALDLSSWR-LAFSGSE 309
Query: 753 RPRINLTNSFSKLFSALGLSPRAVSTSFG-CRVNIAICLQGAS-SPEPSTVYVDLRALRN 810
R++ +FS+ F+A G S RA++ S+G + +C+ A P+ T +
Sbjct: 310 PIRLDTLQAFSQRFAAAGFSARALAPSYGLAEATLYVCVDAAEREPQVETFASTTAGQAD 369
Query: 811 DRVSLVE-RGSPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNASGYF 869
R+ + H L ++E P+T GD +GEIW+ P A GY+
Sbjct: 370 SRLPACGWSDAEHPLRIVE--------------PQTLQVLGDDQVGEIWIAGPSIAQGYW 415
Query: 870 TIYGDESDYADHFSAQLVTGNTGEVYARTGYLGFLRRTEI 909
E+ +A+ G+ + RTG LG +R ++
Sbjct: 416 R--NPEA------TAEAFVERDGQRWLRTGDLGVVRERQL 447
Score = 52.4 bits (120), Expect = 6e-05
Identities = 85/397 (21%), Positives = 161/397 (40%), Gaps = 38/397 (9%)
Query: 1 MLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLASVLNGMHVIFIPYALMKVSPAS 60
+LA+ R +S + + E V L + GL +L +L+G + + PA
Sbjct: 202 LLANERSMSRGFSASREESWVSWLPLYHDMGLMAGLLLPILHGGTLTLMAPNFFLARPAR 261
Query: 61 WMHMITKHRASIAIVKSRDLHWGLLATR----DHKEISLSSLRMLLVADGANPWSLSSCD 116
W+ I+++ + + D + L A R + + LSS R L G+ P L +
Sbjct: 262 WLQAISQYGGTFS--GGPDFAYRLCAERVPQSSLEALDLSSWR--LAFSGSEPIRLDTLQ 317
Query: 117 QFLSVFQSKGVRGDAICPCACSSES-MTVCIXXXXXXXXXXXXXVLSMSGLSYGVVRVDA 175
F F + G A+ P +E+ + VC+ V + + + G A
Sbjct: 318 AFSQRFAAAGFSARALAPSYGLAEATLYVCVDAAEREPQ-----VETFASTTAG----QA 368
Query: 176 ENSLTSLTLQDCGQVMPSCVIVVVKMEGPAYLCKTDEVGEICVLSGATGSGYWGLPGLTN 235
++ L + CG + +V+ + L D+VGEI + + GYW P T
Sbjct: 369 DSRLPA-----CGWSDAEHPLRIVEPQTLQVL-GDDQVGEIWIAGPSIAQGYWRNPEATA 422
Query: 236 TVFRVRPLDSDGEPIGEEHYVRSXXXXXXXXXXXXXXXXSRDGLMTVTGRKHNMDDIIAT 295
F ++ DG+ ++R+ +D L+ + G+ H DI
Sbjct: 423 EAF----VERDGQ-----RWLRTGDLGVVRERQLFIAGRLKD-LIILNGQNHYPQDIEQA 472
Query: 296 VLAVEPMKFIYRGRIAVFSVRVLRD-ERICIVAEQRPDCGEEESFQWM-SRVLQAVDSIH 353
+ + ++ + +GRIA F+V + E + + E + + S + + R+ +
Sbjct: 473 L--EQDIELLRQGRIAAFAVTDEQGIEGVGLALEISRNVRKLISAEMICQRIADGMGERF 530
Query: 354 QVGIYCLALVQPNFLPKTPLGGIHLSECKRRFLEGTL 390
Q+ + L++P LP+T G + S C+ + G+L
Sbjct: 531 QLAPQLILLLEPGTLPRTTSGKLQRSACRSGWQSGSL 567
Score = 41.5 bits (93), Expect = 0.12
Identities = 41/157 (26%), Positives = 72/157 (45%), Gaps = 16/157 (10%)
Query: 483 KVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRP 542
+ L+ EL+++A RIG+ L+E G V D VA+ P GL L+ G GA + +
Sbjct: 2649 QTLSYFELNERANRIGHGLIECG-VQFDDVVAVYAPRGLPLLSLIIGAFKAGAAYLALDE 2707
Query: 543 PHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDM-- 600
HP + RM+ + L+ + + ++ + + + P L +DM
Sbjct: 2708 RHP-----PARSARMLASSAAPVLITLREQLAQV-----QAMLAELPQPPRVLVYEDMLE 2757
Query: 601 -PKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMS 636
++ P Y P E LAYL ++ +TG G+ ++
Sbjct: 2758 HGRRDNPGRYAGP--EHLAYLIYTSGSTGEPKGVMVN 2792
>UniRef50_Q01KB0 Cluster: OSIGBa0135C13.1 protein; n=3; Oryza
sativa|Rep: OSIGBa0135C13.1 protein - Oryza sativa
(Rice)
Length = 2391
Score = 109 bits (263), Expect = 3e-22
Identities = 117/461 (25%), Positives = 189/461 (40%), Gaps = 51/461 (11%)
Query: 466 TSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGR--VNTGDHVALIFPPGLDL 523
T +VI+T +N +G + T ELH A I LL + + GD V LI PGL+
Sbjct: 483 TEKNVIYTWINEEGKLMNRRTYQELHGNASYIAQKLLTSTKPVIKPGDRVLLIHLPGLEF 542
Query: 524 ICAFYGCLYVGAVPVTIRPPHP-QNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEA 582
I AF+GC+ G +PV + PP P Q+ L V I + A +LS S +R+
Sbjct: 543 IDAFFGCIRAGVIPVPVLPPDPMQSGGQALLKVENISKMCNAVAILSTSSYHAAVRAGYI 602
Query: 583 SNVLD--------SKAWP--MTLDTDDMPK---------KKLPIMYRAPTAEMLAYLDFS 623
N++ S WP + TD K +++ P L +L F+
Sbjct: 603 KNIVTLAKRVQKCSAQWPDIPWIQTDSWIKNYRRSSDSFNSDTVLFTKPQPSDLCFLQFT 662
Query: 624 VSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGH 683
+TG G+ ++H + ++MK + L Y +G +++ SG
Sbjct: 663 SGSTGDAKGVMITHEGLIHNVKTMKKRYRSTSKTVLVSWLPQYHDMGLIGGLFTALVSGG 722
Query: 684 HSILIPPSEVEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACV 743
S+L P NP LWL ++ Y + EL + L + K+K +L+ +
Sbjct: 723 TSVLFSPMTFIRNPLLWLQTINDYHGTHSAGPNFAFELVIRRLEAE----KNKVYDLSSM 778
Query: 744 RTCVVVAEERPRINLTNSFSKLFSALGLSPRAVSTSFGCRVN--IAICLQGASSPEPSTV 801
+++A E R F +L GLS ++ +G N C G P V
Sbjct: 779 -VFLMIAAEPVRQKTVRRFIELTQPFGLSEGVLAPGYGLAENCVYVTCAFGECKP----V 833
Query: 802 YVDLRALRNDRVSLVERGSPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQS 861
++D + VE+ +L ++++ + T+ Q D GEIW+ S
Sbjct: 834 FIDWQG--RVCCGYVEQDDTDTL-----------IRIVDPDSLTEHQ-EDGVEGEIWISS 879
Query: 862 PHNASGYFTIYGDESDYADHFSAQLVTGNTGEVYARTGYLG 902
P + GY +G+ F QL + + + RTG LG
Sbjct: 880 PSSGVGY---WGNSEMSQRTFFNQL-KNHPNKKFTRTGDLG 916
Score = 37.9 bits (84), Expect = 1.5
Identities = 53/220 (24%), Positives = 89/220 (40%), Gaps = 26/220 (11%)
Query: 187 CGQVMPSCVIVVVKMEGPAYLCKTDE---VGEICVLSGATGSGYWGLPGLTNTVFRVRPL 243
CG V ++++ P L + E GEI + S ++G GYWG N+ R
Sbjct: 843 CGYVEQDDTDTLIRIVDPDSLTEHQEDGVEGEIWISSPSSGVGYWG-----NSEMSQRTF 897
Query: 244 DSDGEPIGEEHYVRSXXXXXXXXXXXXXXXXSRDGLMTVTGRKHNMDDIIATVLAVEPMK 303
+ + + + R+ +D L+ V GR D+ TV + +
Sbjct: 898 FNQLKNHPNKKFTRTGDLGRTIDGNLFITGRIKD-LIIVAGRNIYSADVEKTVESSSEV- 955
Query: 304 FIYRGRIAVFSV--RVLRDERICI-----------VAEQRPDCGEEESFQWMSRVLQAVD 350
+ G AV + VL + I I +AE R G+ S + ++ + V
Sbjct: 956 -LRPGCCAVVGIPEEVLAQKGISIPDSSDQVGLVVIAEVRE--GKAVSEEVVNNIKARVV 1012
Query: 351 SIHQVGIYCLALVQPNFLPKTPLGGIHLSECKRRFLEGTL 390
H V + + L++P + KT G I EC R+F++ TL
Sbjct: 1013 EEHGVAVASVKLIKPRTICKTTSGKIRRFECMRQFVDNTL 1052
>UniRef50_Q8GGQ3 Cluster: Nonribosomal peptide synthetase; n=2;
Streptomyces|Rep: Nonribosomal peptide synthetase -
Streptomyces atroolivaceus
Length = 1745
Score = 108 bits (260), Expect = 7e-22
Identities = 114/458 (24%), Positives = 180/458 (39%), Gaps = 24/458 (5%)
Query: 458 ILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIF 517
ILR RA +T + G+ V A L ++ + L E+G G+ V L+F
Sbjct: 15 ILRDRADATPHRTALEFIRDDGSEHAV-GYAALDRRVRAVAAALTERGL--RGERVLLLF 71
Query: 518 PPGLDLICAFYGCLYVGAVPVTIR-PPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKL 576
PPG + + AF GCLY GAV V + P + L L T D A L LS++ V
Sbjct: 72 PPGENYVTAFLGCLYAGAVAVPVYVPTGKRGLSAVLATG---ADAG-AVLALSSREVTDA 127
Query: 577 LRSKEASNVLDSKA-WPMTLDTDDMPKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKM 635
+ + W +T D D P AP LA+L ++ +TG G+ +
Sbjct: 128 ITASYPELTTSGLIQWLVTEDIADAAADDWPGTGPAPAD--LAFLQYTSGSTGTPKGVMV 185
Query: 636 SHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIPPSEVEV 695
H + S+ A + P L PY +G L +Y+G LI P
Sbjct: 186 RHDNLVHNSASISTALGVGPDSRGVSWLPPYHDMGLIGGILQPLYAGFPCTLISPMAFVR 245
Query: 696 NPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVVAEERPR 755
+P WL A+S+++ + C + + + K ++L+ + +V AE R
Sbjct: 246 SPYRWLDAISRHRATVSAAPDFAYGECVR----RIPEDKRAELDLSSWQHAMVGAEP-VR 300
Query: 756 INLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGA-SSPEPSTVYVDLRALR-NDRV 813
++F++ F+ G A +G GA EP + D R L V
Sbjct: 301 PATLDAFARAFADSGFDRSAFHPCYGLAEATLFVTGGAPERGEPRVLRADRRELELGQAV 360
Query: 814 SLV--ERGSPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNASGYFTI 871
S + + ++ L G+ V+ +P C GE+WV P +GY+
Sbjct: 361 SAIAGKENKENAAVLTGCGRSRSEDVVVVVDPAEGRACPPGGTGEVWVSGPTVTAGYW-- 418
Query: 872 YGDESDYADHFSAQLVTGNTGEVYARTGYLGFLRRTEI 909
+ D + + G + RTG LGF E+
Sbjct: 419 --GRPELTDEVFRATLESHPGRHFLRTGDLGFALGDEL 454
Score = 107 bits (257), Expect = 2e-21
Identities = 104/373 (27%), Positives = 159/373 (42%), Gaps = 25/373 (6%)
Query: 29 ETGLWHAVLASVLNGMHVIFI-PYALMKVSPASWMHMITKHRASIAIVKSRDLHWGLLAT 87
+ GL +L + G I P A ++ SP W+ I++HRA+++ D +G
Sbjct: 218 DMGLIGGILQPLYAGFPCTLISPMAFVR-SPYRWLDAISRHRATVSAAP--DFAYGECVR 274
Query: 88 R----DHKEISLSSLRMLLVADGANPWSLSSCDQFLSVFQSKGVRGDAICPCACSSESMT 143
R E+ LSS + +V GA P ++ D F F G A PC +E+ T
Sbjct: 275 RIPEDKRAELDLSSWQHAMV--GAEPVRPATLDAFARAFADSGFDRSAFHPCYGLAEA-T 331
Query: 144 VCIXXXXXXXXXXXXXVLSMSGLSYG-VVRVDA--ENSLTSLTLQDCGQVMPSCVIVVVK 200
+ + L G V A EN + L CG+ V+VVV
Sbjct: 332 LFVTGGAPERGEPRVLRADRRELELGQAVSAIAGKENKENAAVLTGCGRSRSEDVVVVVD 391
Query: 201 -MEGPAYLCKTDEVGEICVLSGATGSGYWGLPGLTNTVFRVRPLDSDGEPIGEEHYVRSX 259
EG A C GE+ V +GYWG P LT+ VFR G H++R+
Sbjct: 392 PAEGRA--CPPGGTGEVWVSGPTVTAGYWGRPELTDEVFRATLESHPGR-----HFLRTG 444
Query: 260 XXXXXXXXXXXXXXXSRDGLMTVTGRKHNMDDIIATVLAVEPMKFIYRGRIAVFSVRVLR 319
++D L+ V GR H DI + P+ + R AVFS
Sbjct: 445 DLGFALGDELFVTGRAKD-LLVVRGRNHYPQDIEQSAEHAHPL--LQPTRAAVFSHDDGT 501
Query: 320 DERICIVAEQRPDCGEEESFQWMSRVLQAVDSIHQVGIYCLALVQPNFLPKTPLGGIHLS 379
+ER +V E E + + ++ V +AV + H + ++ + LV+P +P+T G + S
Sbjct: 502 EERAVLVHEVVRGFDPERAPEVITAVRKAVTAEHGLSLHEVVLVRPGAIPRTTSGKVRRS 561
Query: 380 ECKRRFLEGTLHP 392
C+ R+L+GTL P
Sbjct: 562 TCRERWLDGTLQP 574
>UniRef50_Q0LN70 Cluster: Amino acid adenylation; n=1; Herpetosiphon
aurantiacus ATCC 23779|Rep: Amino acid adenylation -
Herpetosiphon aurantiacus ATCC 23779
Length = 2820
Score = 108 bits (260), Expect = 7e-22
Identities = 114/455 (25%), Positives = 193/455 (42%), Gaps = 44/455 (9%)
Query: 458 ILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIF 517
+LR A + + LN + A L+ AEL ++A ++ L G+ V L+
Sbjct: 37 VLRLNALEAPEQQAYRFLNGQFATED-LSYAELDRRARQVAVRLQALNA--QGERVVLLN 93
Query: 518 PPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKAT---LVLSNQSVI 574
PGLD I +F GCLY GA+ V + PP Q L LP R++ V+ AT ++ Q V
Sbjct: 94 DPGLDYIVSFLGCLYAGAIAVPLYPPKLQQLERHLP--RLLAVVANATPRFALIDRQFVS 151
Query: 575 KLLRSKEASNVLDSKAWPMTLDTDDMPKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIK 634
++ R + L + W + + D ++P + LA+L ++ +TG G+
Sbjct: 152 QIERLLAVAPQLQALQWLICDEKVDAGAWQVPQL----ETHNLAFLQYTSGSTGQPKGVM 207
Query: 635 MSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIPPSEVE 694
+SH + + ++ + + L PY +G L +YS +L+ P
Sbjct: 208 VSHGNLLANLAQIQQRFGHDATSQGVIWLPPYHDMGLIGGILQPLYSRFPVVLMSPVAFL 267
Query: 695 VNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVVAEERP 754
P WL A+S Y+ + ELC + + + ++L R AE
Sbjct: 268 QQPWRWLQAISDYRATTSGGPNFAYELCVR----KITPAQRATLDLRSWRVAFNGAEP-I 322
Query: 755 RINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPSTVYVDLRALRNDRVS 814
R N+ F++ F+ +G P A ++G + + GA P
Sbjct: 323 RPNVLRQFAETFADVGFDPAAFYPTYG-MAEATLMVSGAHLPR----------------- 364
Query: 815 LVERGSPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNASGYFTIYGD 874
+ + P L+ G ++ +++ +P ++ +GEIW++ P A GY+
Sbjct: 365 -LAQPEPE---LISCGTVIDEHELLIVDPTNLEVLPETAVGEIWLRGPSVAHGYWA--SA 418
Query: 875 ESDYADHFSAQLVTGNTGEVYARTGYLGFLRRTEI 909
E A F+AQ N E + RTG LGFLR E+
Sbjct: 419 ELSKAT-FAAQPRERN--EHFLRTGDLGFLRNGEL 450
Score = 64.5 bits (150), Expect = 1e-08
Identities = 50/209 (23%), Positives = 89/209 (42%), Gaps = 10/209 (4%)
Query: 184 LQDCGQVMPSCVIVVVKMEGPAYLCKTDEVGEICVLSGATGSGYWGLPGLTNTVFRVRPL 243
L CG V+ +++V L +T VGEI + + GYW L+ F +P
Sbjct: 372 LISCGTVIDEHELLIVDPTNLEVLPET-AVGEIWLRGPSVAHGYWASAELSKATFAAQPR 430
Query: 244 DSDGEPIGEEHYVRSXXXXXXXXXXXXXXXXSRDGLMTVTGRKHNMDDIIATVLAVEPMK 303
+ + EH++R+ D L+ + G+ H D+ +V P
Sbjct: 431 ERN------EHFLRTGDLGFLRNGELYINGRLND-LIIIRGQNHYAHDLELSVDQAHPA- 482
Query: 304 FIYRGRIAVFSVRVLRDERICIVAEQRPDCGEEESFQWMSRVLQAVDSIHQVGIYCLALV 363
+ A FS+ V E++ ++ E R + + + M+ + Q++ H + Y + L+
Sbjct: 483 -LQPQACAAFSLDVAGVEQLVLMQELRREQRQHDPAPIMAAIRQSLAQTHGLQAYAIVLL 541
Query: 364 QPNFLPKTPLGGIHLSECKRRFLEGTLHP 392
+P LP+T G + C+ FL G L P
Sbjct: 542 RPGQLPRTSSGKLQRYRCRELFLGGELTP 570
>UniRef50_Q211N2 Cluster: AMP-dependent synthetase and ligase
precursor; n=1; Rhodopseudomonas palustris BisB18|Rep:
AMP-dependent synthetase and ligase precursor -
Rhodopseudomonas palustris (strain BisB18)
Length = 701
Score = 108 bits (259), Expect = 9e-22
Identities = 100/431 (23%), Positives = 185/431 (42%), Gaps = 19/431 (4%)
Query: 473 TLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLY 532
+ L++ GAV++ AEL +A + L + + G V L+F P +D + AF C +
Sbjct: 28 SFLDSHGAVAERCGAAELAARAAAVAGFL--ERQTAPGAPVLLVFQPSVDFLVAFLACQW 85
Query: 533 VGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWP 592
G + V I PP H + ++ + S A + L+ L +++ VL + W
Sbjct: 86 SGRLAVPINPPRR---HRLIERLQAVAADSGAAVALTGGVAESALWLADSA-VLAAIRWQ 141
Query: 593 MTLDTDDMPKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACE 652
D P P+ P A ++ ++ +T + G+++SH + + M+ A
Sbjct: 142 DIGGIDSDPALAGPLREVDPAAT--CFIQYTSGSTALPKGVEVSHDNLMADMARMQDAWG 199
Query: 653 LYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIPPSEVEVNPALWLSAVSQYKVRDT 712
L PS + L + LG L ++++G + + P+ P LWL A+S+++ T
Sbjct: 200 LSPSSTMVTWLPAFHDLGLIFGLLQTLFTGCPVVQMAPNSFLQRPVLWLEAISRFRGTHT 259
Query: 713 FCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVVAEE-RPRINLTNSFSKLFSALGL 771
+LC++ + + +G++L+ + + AE PR+ +F + F G
Sbjct: 260 AAPSFAYDLCSRRIPPE----QREGLDLSSLVMAMNAAEPIDPRV--MQNFIENFGPHGF 313
Query: 772 SPRAVSTSFGCRVNIAICLQGASSPEPSTVYVDLRALRNDRVSLVERGSPHSLCLMESGK 831
+ ++G + + P +D AL + R++ + + + SG
Sbjct: 314 DDTTFAPAYGLAESTLAVTASPVAVAPRLFTLDATALEDGRIAF-DGAAARRTAIAGSGT 372
Query: 832 LLPGVKVITANPETKGQCGDSHLGEIWVQSPHNASGYFTIYGDESDYADHFSAQLVTGNT 891
L V + +PET + +GEIW+ P A GY+ +ES A F + +
Sbjct: 373 PLADVTIAIVDPETGRRQPADRVGEIWLGGPTIARGYWR-RPEES--AATFGVHIAGEDD 429
Query: 892 GEVYARTGYLG 902
Y RTG LG
Sbjct: 430 TIGYLRTGDLG 440
Score = 42.3 bits (95), Expect = 0.068
Identities = 80/393 (20%), Positives = 139/393 (35%), Gaps = 16/393 (4%)
Query: 1 MLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLASVLNGMHVIFIPYALMKVSPAS 60
++A + A + MV L + GL +L ++ G V+ + P
Sbjct: 187 LMADMARMQDAWGLSPSSTMVTWLPAFHDLGLIFGLLQTLFTGCPVVQMAPNSFLQRPVL 246
Query: 61 WMHMITKHRASIAIVKS--RDLHWGLLATRDHKEISLSSLRMLLVADGANPWSLSSCDQF 118
W+ I++ R + S DL + + + LSSL M + A A P F
Sbjct: 247 WLEAISRFRGTHTAAPSFAYDLCSRRIPPEQREGLDLSSLVMAMNA--AEPIDPRVMQNF 304
Query: 119 LSVFQSKGVRGDAICPCACSSESMTVCIXXXXXXXXXXXXXVLSMSGLSYGVVRVDAENS 178
+ F G P +ES T+ + L + L G + D +
Sbjct: 305 IENFGPHGFDDTTFAPAYGLAES-TLAVTASPVAVAPRLFT-LDATALEDGRIAFDGAAA 362
Query: 179 LTSLTLQDCGQVMPSCVIVVVKMEGPAYLCKTDEVGEICVLSGATGSGYWGLPGLTNTVF 238
+ + G + I +V E D VGEI + GYW P + F
Sbjct: 363 RRT-AIAGSGTPLADVTIAIVDPE-TGRRQPADRVGEIWLGGPTIARGYWRRPEESAATF 420
Query: 239 RVRPLDSDGEPIGEEHYVRSXXXXXXXXXXXXXXXXSRDGLMTVTGRKHNMDDIIATVLA 298
V + + + IG Y+R+ +D L+ ++G H DI A
Sbjct: 421 GVH-IAGEDDTIG---YLRTGDLGAMIDGELCVTGRIKD-LIILSGANHYPQDIERAAQA 475
Query: 299 VEPMKFIYRGRIAVFSVRVLRD-ERICIVAEQRPDCGEEESFQWMSRVLQAVDSIHQVGI 357
+ G A FS+ + E++ +V E + S + AV ++ +
Sbjct: 476 AHSALRVDSG--AAFSIAGEQGAEQVVLVQELERTQRRSDPAPLFSAISTAVWQTLELQL 533
Query: 358 YCLALVQPNFLPKTPLGGIHLSECKRRFLEGTL 390
+ LV+P + +T G I + ++ + G L
Sbjct: 534 SRIVLVEPGAVLRTSSGKIQRAANRQAWRAGAL 566
>UniRef50_UPI000011F913 Cluster: UPI000011F913 related cluster; n=1;
unknown|Rep: UPI000011F913 UniRef100 entry - unknown
Length = 1261
Score = 107 bits (258), Expect = 1e-21
Identities = 108/435 (24%), Positives = 186/435 (42%), Gaps = 23/435 (5%)
Query: 479 GAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPV 538
GA + +T A L + + L + RV GD V + PG + AF CLYVGAVPV
Sbjct: 59 GAAEEDVTYAALDRAVRAAAHALGD--RVTPGDRVLVSCGPGTGFLRAFLACLYVGAVPV 116
Query: 539 TIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTD 598
+ P P I + A LVL++++ +R + D+ +T+ T
Sbjct: 117 PV--PVPGGFGRQEARTTAIAGDTGARLVLTDEASAGAVR-RWLDGERDALP-ELTVATV 172
Query: 599 DMPKKK--LPIMYRAPTA-EMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYP 655
+ ++ + P E L +L ++ +T G+ + H A+ R M+ +
Sbjct: 173 ESAQEAGDADAWHEWPVGPEALCFLQYTSGSTSEPKGVMVPHGALVHNLRLMRDCHGWHG 232
Query: 656 SRHIALCLDPYCGLGFALWCLSSIYSGHHSILIPPSEVEVNPALWLSAVSQYKVRDTFCS 715
L Y +G L+ +Y G ++L+ ++ P WL + +++ +
Sbjct: 233 GMTWCSWLPAYHDMGLIAMMLAPLYLGGTAVLMSSTDFLKRPVSWLRLIERHRAEISCAP 292
Query: 716 YGVMELCTKGLGSSVNQLKSKGINLACVRTCVVVAEERPRINLTNSFSKLFSALGLSPRA 775
+LC + L + ++ G++L+ R AE LT F++ F+ G S R+
Sbjct: 293 NFAYDLCARRL----TEEQTAGLDLSSWRYACNGAEPVDAATLTR-FAERFAGAGFSARS 347
Query: 776 VSTSFGCRVNIAICLQGASSPEPSTVY-VDLRALRNDRVSLVERGSPHSLCLMESGKLLP 834
+ +G + + G + P V D AL V+ E GS L+ SG ++
Sbjct: 348 LLPGYGL-AEATLYVSGTRADRPPVVLRADPSALAGGEVAEAEPGSTAQE-LVSSG-IVR 404
Query: 835 GVKVITANPETKGQCGDSHLGEIWVQSPHNASGYFTIYGDESDYADHFSAQLVTGNTGEV 894
G+ V +P T+ + + +GEIW++ A GY + + F A G+TG
Sbjct: 405 GLDVRVVDPGTRAELSEGRVGEIWIRGGSVALGY---WNRAEETRRTFGAATADGDTG-- 459
Query: 895 YARTGYLGFLRRTEI 909
+ RTG LG LR E+
Sbjct: 460 FLRTGDLGALRAGEL 474
Score = 44.8 bits (101), Expect = 0.013
Identities = 65/249 (26%), Positives = 92/249 (36%), Gaps = 12/249 (4%)
Query: 2 LAHCRMLSVACNYTEGEHMVCV-LDFKRETGLWHAVLASV-LNGMHVIFIPYALMKVSPA 59
L H L C+ G C L + GL +LA + L G V+ +K P
Sbjct: 217 LVHNLRLMRDCHGWHGGMTWCSWLPAYHDMGLIAMMLAPLYLGGTAVLMSSTDFLK-RPV 275
Query: 60 SWMHMITKHRASIAIVK--SRDLHWGLLATRDHKEISLSSLRMLLVADGANPWSLSSCDQ 117
SW+ +I +HRA I+ + DL L + LSS R +GA P ++ +
Sbjct: 276 SWLRLIERHRAEISCAPNFAYDLCARRLTEEQTAGLDLSSWR--YACNGAEPVDAATLTR 333
Query: 118 FLSVFQSKGVRGDAICPCACSSESMTVCIXXXXXXXXXXXXXVLSMSGLSYGVVRVDAEN 177
F F G ++ P +E+ T+ + S L+ G V +AE
Sbjct: 334 FAERFAGAGFSARSLLPGYGLAEA-TLYVSGTRADRPPVVLRA-DPSALAGGEV-AEAEP 390
Query: 178 SLTSLTLQDCGQVMPSCVIVVVKMEGPAYLCKTDEVGEICVLSGATGSGYWGLPGLTNTV 237
T+ L G V V VV G VGEI + G+ GYW T
Sbjct: 391 GSTAQELVSSGIVRGLDVRVV--DPGTRAELSEGRVGEIWIRGGSVALGYWNRAEETRRT 448
Query: 238 FRVRPLDSD 246
F D D
Sbjct: 449 FGAATADGD 457
>UniRef50_Q9FB23 Cluster: Peptide synthetase NRPS5-4-3; n=1;
Streptomyces verticillus|Rep: Peptide synthetase
NRPS5-4-3 - Streptomyces verticillus
Length = 2675
Score = 107 bits (258), Expect = 1e-21
Identities = 115/455 (25%), Positives = 186/455 (40%), Gaps = 27/455 (5%)
Query: 455 ISQILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVA 514
I I R A+ T + L S + A++ ++A + +L ++G G+ V
Sbjct: 7 IVDIARRHAERTPARPAYAFLPDGETESVRFSFADIDRRARAVAAVLQDRGLA--GERVL 64
Query: 515 LIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVI 574
+ +P G + + AF GCLY G V V P L +R + A + ++ +
Sbjct: 65 VAYPSGPEYVQAFLGCLYAGVVAVPCDEPRSGPSAERLAGIRADARPALALTAGAPEAGL 124
Query: 575 KLLRSKEASNVLDSKAWPMTLDTDDMPKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIK 634
L + + + V DS A T D P+ P A LA+L ++ +T G+
Sbjct: 125 AGLATLDVAGVPDSAAGAWT----D------PVA--GPDA--LAFLQYTSGSTRRPRGVM 170
Query: 635 MSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIPPSEVE 694
+ H + + R + AC + +G L +Y G S+L+PP
Sbjct: 171 VGHGNLLANERCIAAACGHDRDSTFVGWAPFFHDMGLVANLLQPLYLGSLSVLMPPMAFL 230
Query: 695 VNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVVAEERP 754
PA WL AVS+Y+ + +LC +G + G++L+ + AE
Sbjct: 231 QRPARWLRAVSRYRAHTSGGPNFAYDLCVDRVGED----ERAGLDLSGWKVAYNGAEP-V 285
Query: 755 RINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPSTVYVDLRALRNDRVS 814
R + F+ F+ G +P A ++G + G P T+ D ALR R+
Sbjct: 286 RADTLRRFTDRFAPHGFTPGAHFPTYGLAEATLLVATGPKGVPPRTLTADRAALRAGRLR 345
Query: 815 LVERGSPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNASGYFTIYGD 874
G L L+ +G + +P T +C +GE+WV+ P A GYF G
Sbjct: 346 PAGPGEA-GLELVGNGTAGLDTTLRIVDPATARECPPGEVGEVWVRGPGVARGYF---GR 401
Query: 875 ESDYADHFSAQLVTGNTGEVYARTGYLGFLRRTEI 909
+ A +A+L G G Y RTG LG L E+
Sbjct: 402 PRESAPLLAARL-PGGEGP-YLRTGDLGALHDGEL 434
Score = 55.6 bits (128), Expect = 7e-06
Identities = 87/402 (21%), Positives = 151/402 (37%), Gaps = 20/402 (4%)
Query: 1 MLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLASV-LNGMHVIFIPYALMKVSPA 59
+LA+ R ++ AC + V F + GL +L + L + V+ P A ++ PA
Sbjct: 176 LLANERCIAAACGHDRDSTFVGWAPFFHDMGLVANLLQPLYLGSLSVLMPPMAFLQ-RPA 234
Query: 60 SWMHMITKHRASIAIVKS--RDLHWGLLATRDHKEISLSSLRMLLVADGANPWSLSSCDQ 117
W+ ++++RA + + DL + + + LS ++ +GA P + +
Sbjct: 235 RWLRAVSRYRAHTSGGPNFAYDLCVDRVGEDERAGLDLSGWKVAY--NGAEPVRADTLRR 292
Query: 118 FLSVFQSKGVRGDAICPCACSSESMTVCIXXXXXXXXXXXXXVLSMSGLSYGVVRVDAEN 177
F F G A P +E+ + + L G +R A
Sbjct: 293 FTDRFAPHGFTPGAHFPTYGLAEA--TLLVATGPKGVPPRTLTADRAALRAGRLR-PAGP 349
Query: 178 SLTSLTLQDCGQVMPSCVIVVVKMEGPAYLCKTDEVGEICVLSGATGSGYWGLPGLTNTV 237
L L G + +V A C EVGE+ V GY+G P +
Sbjct: 350 GEAGLELVGNGTAGLDTTLRIVD-PATARECPPGEVGEVWVRGPGVARGYFGRPRES--- 405
Query: 238 FRVRPLDSDGEPIGEEHYVRSXXXXXXXXXXXXXXXXSRDGLMTVTGRKHNMDDIIATVL 297
PL + P GE Y+R+ +D L+ + G+ H+ D+ T
Sbjct: 406 ---APLLAARLPGGEGPYLRTGDLGALHDGELFLTGRHKD-LIVIRGQNHHPHDLERTAE 461
Query: 298 AVEPMKFIYRGRIAVFSVRVLRDERICIVAEQRPDCGEEESFQWMSRVLQAVDSIHQVGI 357
P + A F+V ER+ +V E + + V A+ + H V
Sbjct: 462 QAHPA--LRPTCAAAFAVPGDGAERLVLVCELTSYRAVDPAAV-AEAVRAALAARHGVAP 518
Query: 358 YCLALVQPNFLPKTPLGGIHLSECKRRFLEGTLHPSNVLMCP 399
+ L +++ +PKT G + C+ +L+GTL + P
Sbjct: 519 HTLVVLRRGGIPKTTSGKVRRGHCRTAYLDGTLPVHTAVRLP 560
>UniRef50_A1T3T7 Cluster: AMP-dependent synthetase and ligase; n=1;
Mycobacterium vanbaalenii PYR-1|Rep: AMP-dependent
synthetase and ligase - Mycobacterium vanbaalenii
(strain DSM 7251 / PYR-1)
Length = 706
Score = 107 bits (258), Expect = 1e-21
Identities = 120/461 (26%), Positives = 192/461 (41%), Gaps = 32/461 (6%)
Query: 455 ISQILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVA 514
+S+ LR A D I + L+ + V+ LT L +A + LL++G G V
Sbjct: 7 LSRRLRRHADEFPDERILSFLDDRLEVADSLTFGRLDDRARSVAAGLLDRGM--GGAPVV 64
Query: 515 LIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVI 574
L +PPGLD + AF GCLY GA+ V P + T + ++ S A VL++ +
Sbjct: 65 LSYPPGLDFVSAFCGCLYAGAIAVPAALPQSRR---TAERLAAVLKDSAARCVLTSAAHR 121
Query: 575 KLLRSKE--ASNVLDSKAWPMTLDTDDMPKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAG 632
L S A +V+D + TD +P + P + +A+L ++ +T G
Sbjct: 122 AELYSHAGAAPSVVD------VIATDVLPSRPGDGRVALPDPDQVAFLQYTSGSTRSPRG 175
Query: 633 IKMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIPPSE 692
+ + H + + S++ L + +G L I+S L+ P+
Sbjct: 176 VMVRHGDLAANLNSLREILAFDDHATGVSWLPVFHDMGLIAGVLLPIWSARPQFLMAPAT 235
Query: 693 VEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVV--A 750
NP WL A+S+Y G G + V+ ++ G +R V
Sbjct: 236 FVRNPLSWLEAISRYGGTHQ----GAPNF---GYQACVDAARAAGATTFDLRNWRVAWNG 288
Query: 751 EERPRINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPST-VYVDLRALR 809
E R + + F F+ G +S +G + + G+ +P+T + VD L
Sbjct: 289 AEPVRPDTLHQFRDQFALNGFGSECLSPGYGL-AEATLVVSGSDGSKPATELTVDESELH 347
Query: 810 NDRVSLVERGSPHSLCLMESGKLLPGVKVITANPETKGQCGDSH-LGEIWVQSPHNASGY 868
+V P L+ SG+ G +V + G+ + H LGEIWV+S A GY
Sbjct: 348 VGQVRPRIDDGPGVKRLVGSGRPAAGTEVQIVRAD--GRVAEPHTLGEIWVRSDSVAQGY 405
Query: 869 FTIYGDESDYADHFSAQLVTGNTGEVYARTGYLGFLRRTEI 909
+ G+ S F A L TG Y RTG LGF+ E+
Sbjct: 406 WNNPGETS---GTFGACLTTGE--GPYLRTGDLGFVDDGEL 441
Score = 45.6 bits (103), Expect = 0.007
Identities = 74/355 (20%), Positives = 128/355 (36%), Gaps = 14/355 (3%)
Query: 29 ETGLWHAVLASVLNGMHVIFIPYALMKVSPASWMHMITKHRASIAIVKSRDLHWGLLATR 88
+ GL VL + + + A +P SW+ I+++ + + + A R
Sbjct: 211 DMGLIAGVLLPIWSARPQFLMAPATFVRNPLSWLEAISRYGGTHQGAPNFGYQACVDAAR 270
Query: 89 DHKEISLSSLRMLLVADGANPWSLSSCDQFLSVFQSKGVRGDAICPCACSSESMTVCIXX 148
+ + +GA P + QF F G + + P +E+ T+ +
Sbjct: 271 AAGATTFDLRNWRVAWNGAEPVRPDTLHQFRDQFALNGFGSECLSPGYGLAEA-TLVVSG 329
Query: 149 XXXXXXXXXXXVLSMSGLSYGVVRVDAENSLTSLTLQDCGQVMPSCVIVVVKMEGPAYLC 208
V S L G VR ++ L G+ + +V+ +G +
Sbjct: 330 SDGSKPATELTV-DESELHVGQVRPRIDDGPGVKRLVGSGRPAAGTEVQIVRADGR--VA 386
Query: 209 KTDEVGEICVLSGATGSGYWGLPGLTNTVFRVRPLDSDGEPIGEEHYVRSXXXXXXXXXX 268
+ +GEI V S + GYW PG T+ F GE Y+R+
Sbjct: 387 EPHTLGEIWVRSDSVAQGYWNNPGETSGTF------GACLTTGEGPYLRTGDLGFVDDGE 440
Query: 269 XXXXXXSRDGLMTVTGRKHNMDDIIATVLAVEPMKFIYRGRIAVFSVRVLRDERICIVAE 328
D ++ + G + DI TV P G AV V + V+E
Sbjct: 441 LFVIGRLND-VIVIRGVNYYPHDIEYTVERSHPALQPDAG--AVIGVERSGRVDLVSVSE 497
Query: 329 QRPDCGEE-ESFQWMSRVLQAVDSIHQVGIYCLALVQPNFLPKTPLGGIHLSECK 382
R D + + + +AV HQ+ + + L++P +PKT G I + C+
Sbjct: 498 IRRDLVDSIVGDDIVDAIRRAVARDHQLALQRVVLLRPGGMPKTSSGKIQRARCR 552
Score = 38.7 bits (86), Expect = 0.84
Identities = 15/31 (48%), Positives = 24/31 (77%)
Query: 952 VFVVGALDETIMLRGMRYHPIDIENSVMRCH 982
+FV+G L++ I++RG+ Y+P DIE +V R H
Sbjct: 441 LFVIGRLNDVIVIRGVNYYPHDIEYTVERSH 471
>UniRef50_A1WM65 Cluster: AMP-dependent synthetase and ligase; n=1;
Verminephrobacter eiseniae EF01-2|Rep: AMP-dependent
synthetase and ligase - Verminephrobacter eiseniae
(strain EF01-2)
Length = 593
Score = 107 bits (256), Expect = 2e-21
Identities = 102/449 (22%), Positives = 185/449 (41%), Gaps = 18/449 (4%)
Query: 455 ISQILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVA 514
I + L AQ+ + +T L +VLT +L +A G L + G + V
Sbjct: 13 ILECLEHYAQTRPEERAYTFLVNGDDQERVLTYGDLRSRAVAYGQHLRDCGLSHKA--VL 70
Query: 515 LIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVI 574
L+FP GLD I AF+ C Y GAV V + + L R I+ S+ VL+ + +
Sbjct: 71 LLFPSGLDFIIAFFACAYAGAVSVPANLARNSHHYARL---RQIILDSETRAVLTTRDLR 127
Query: 575 KLLRSKEASNVLDSKAWPMTLDTDDMPKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIK 634
+ + +D+ + ++D+ + PT E LA+L ++ +TG G+
Sbjct: 128 NSIGEGLLGSGVDTSHVAVFCESDE---PVVTCSVTLPTQEQLAFLQYTSGSTGEPKGVM 184
Query: 635 MSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIPPSEVE 694
++HA + + R+++ + +L A L + +G L + G H + + P
Sbjct: 185 ITHAQLVANERAIQRSADLPEHLAGAGWLPQFHDMGLIGATLQPVALGGHYVFMSPLHFL 244
Query: 695 VNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVVAEERP 754
P WL +S Y+ T +ELC K + + ++L+ + T + E
Sbjct: 245 QRPLRWLKMISHYRAVATAAPNFALELCAKAQPDD----EIEALDLSTLST-IFCGAEPV 299
Query: 755 RINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPSTVYVDLRALRNDRVS 814
+ F FS GL A+ +G + G + T++V AL R
Sbjct: 300 NADAIERFELRFSRFGLRSDAIKPCYGLAEATLMVSGGVAPNNLRTLFVGRDALTVGRAE 359
Query: 815 LVERGSPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNASGYFTIYGD 874
+ + + ++ G+ + +++ +P T + +GE+W ASGY+
Sbjct: 360 VQHDSAQPTQTVVCCGRPVLEHRIVIVDPSTGCILSNGQVGEVWFAGSSVASGYW----- 414
Query: 875 ESDYADHFSAQLVTGNTGEVYARTGYLGF 903
+ A + + +T + RTG LGF
Sbjct: 415 RNPVATMETFKAMTSCGEGPFMRTGDLGF 443
Score = 64.5 bits (150), Expect = 1e-08
Identities = 78/356 (21%), Positives = 135/356 (37%), Gaps = 15/356 (4%)
Query: 29 ETGLWHAVLASVLNGMHVIFIPYALMKVSPASWMHMITKHRASIAIVKSRDLHWGLLATR 88
+ GL A L V G H +F+ P W+ MI+ +RA + L A
Sbjct: 218 DMGLIGATLQPVALGGHYVFMSPLHFLQRPLRWLKMISHYRAVATAAPNFALELCAKAQP 277
Query: 89 DHKEISLSSLRMLLVADGANPWSLSSCDQFLSVFQSKGVRGDAICPCACSSESMTVCIXX 148
D + +L + + GA P + + ++F F G+R DAI PC +E+ T+ +
Sbjct: 278 DDEIEALDLSTLSTIFCGAEPVNADAIERFELRFSRFGLRSDAIKPCYGLAEA-TLMVSG 336
Query: 149 XXXXXXXXXXXVLSMSGLSYGVVRVDAENSLTSLTLQDCGQVMPSCVIVVVKMEGPAYLC 208
V L+ G V +++ + T+ CG+ + IV+V +
Sbjct: 337 GVAPNNLRTLFV-GRDALTVGRAEVQHDSAQPTQTVVCCGRPVLEHRIVIVD-PSTGCIL 394
Query: 209 KTDEVGEICVLSGATGSGYWGLPGLTNTVFRVRPLDSDGEPIGEEHYVRSXXXXXXXXXX 268
+VGE+ + SGYW P T F+ GE ++R+
Sbjct: 395 SNGQVGEVWFAGSSVASGYWRNPVATMETFKAM------TSCGEGPFMRTGDLGFFHNEG 448
Query: 269 XXXXXXSRDGLMTVTGRKHNMDDIIATVLAVEPMKFIYRGRIAVFSVRVLRDERICIVAE 328
++ L+ GR DI +T+ ++ + AVF+ + E
Sbjct: 449 LFITGRIKE-LIIFRGRNLYPHDIESTL--IKTSAIFSEVQAAVFTANSDDGSNVVAYVE 505
Query: 329 --QRPDCGEEESFQWMSRVLQ-AVDSIHQVGIYCLALVQPNFLPKTPLGGIHLSEC 381
+R FQ ++ L+ AV +H V + + + +P+T G I C
Sbjct: 506 LPRRTKAYPGLEFQSVAHTLRMAVAQVHDVHLRDIYFLSHGKIPRTSSGKIQRKRC 561
>UniRef50_A0FRX9 Cluster: AMP-dependent synthetase and ligase; n=1;
Burkholderia phymatum STM815|Rep: AMP-dependent
synthetase and ligase - Burkholderia phymatum STM815
Length = 676
Score = 106 bits (255), Expect = 3e-21
Identities = 116/463 (25%), Positives = 191/463 (41%), Gaps = 31/463 (6%)
Query: 457 QILRWRAQSTSDHVIFTLLNAKGAVSK--VLTCAELHKKAERIGNLLLEKGRVNTGDHVA 514
++ R RA++ + FT ++ G + V+T +L +A +I LL + R + GD V
Sbjct: 104 EVTRRRAEADTIEPAFTFIDYTGMQPEDHVITNRQLDLRARQIAALL--QTRAHAGDRVL 161
Query: 515 LIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVI 574
L+F G+D +CA +GC Y G V V PP L L V + AT+ L+ Q+++
Sbjct: 162 LLFSAGIDYLCALFGCFYAGMVAVPAYPPLNPRLRERLAAVS---EDCTATVALTTQNIL 218
Query: 575 KLLRSKEASNVLDSKA---WPMTLDTDDMPKKKLPIMYRAPTA--EMLAYLDFSVSTTGM 629
L +A+ + S A W M + T P L +RAP A E LA L ++ +TG
Sbjct: 219 DQLH--DAAPLPPSLARLNW-MPIGT---PLDALERAWRAPRADRESLAILQYTSGSTGT 272
Query: 630 LAGIKMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIP 689
G+ ++H + S ++ + + P H L PY +G L S +G +
Sbjct: 273 PKGVMVTHGNLLSNTAAIALHLQFAPDDHHLTWLPPYHDMGLMGAILGSFCAGVPVSFMA 332
Query: 690 PSEVEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVV 749
P+ P WL+ +S+ + + ELC + V + ++L+
Sbjct: 333 PAAFLRRPERWLTEISKRRCTVSGAPNFAYELCFSKIRPEVLET----LDLSSWSLAYSG 388
Query: 750 AEERPRINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPSTVYVDLRALR 809
AE LT F+ F G A +G P + +D
Sbjct: 389 AEPVQADTLTR-FTARFGRCGFRHEAFYPCYGMAETTLFVTGKRREAPPRVLRIDGPRFA 447
Query: 810 NDRVSLVERGSPHSLCLME---SGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNAS 866
+ + + + E G + G V +P + D ++GEIWV A+
Sbjct: 448 AGQCHPLGGAGNSGMAVREVVSCGIVATGHDVAVVDPNSGKPLADGNVGEIWVSGASVAN 507
Query: 867 GYFTIYGDESDYADHFSAQLVTGNTGEVYARTGYLGFLRRTEI 909
GY+ ++ F A+L G + Y RTG LGF+ E+
Sbjct: 508 GYWRRPEATNEV---FHARL-PGRPDD-YLRTGDLGFILNGEL 545
Score = 76.2 bits (179), Expect = 5e-12
Identities = 96/398 (24%), Positives = 161/398 (40%), Gaps = 26/398 (6%)
Query: 1 MLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLASVLNGMHVIFIPYALMKVSPAS 60
+L++ +++ + +H + L + GL A+L S G+ V F+ A P
Sbjct: 283 LLSNTAAIALHLQFAPDDHHLTWLPPYHDMGLMGAILGSFCAGVPVSFMAPAAFLRRPER 342
Query: 61 WMHMITKHRASIAIVKS--RDLHWGLLATRDHKEISLSSLRMLLVADGANPWSLSSCDQF 118
W+ I+K R +++ + +L + + + + LSS L GA P + +F
Sbjct: 343 WLTEISKRRCTVSGAPNFAYELCFSKIRPEVLETLDLSSWS--LAYSGAEPVQADTLTRF 400
Query: 119 LSVFQSKGVRGDAICPCACSSESMTVCIXXXXXXXXXXXXXVLSMSGLSYGVVRVD---- 174
+ F G R +A PC +E+ T+ + VL + G + +
Sbjct: 401 TARFGRCGFRHEAFYPCYGMAET-TLFVTGKRREAPPR---VLRIDGPRFAAGQCHPLGG 456
Query: 175 AENS-LTSLTLQDCGQVMPSCVIVVVKMEGPAYLCKTDEVGEICVLSGATGSGYWGLPGL 233
A NS + + CG V + VV L + VGEI V + +GYW P
Sbjct: 457 AGNSGMAVREVVSCGIVATGHDVAVVDPNSGKPLADGN-VGEIWVSGASVANGYWRRPEA 515
Query: 234 TNTVFRVRPLDSDGEPIGEEHYVRSXXXXXXXXXXXXXXXXSRDGLMTVTGRKHNMDDII 293
TN VF R G P + Y+R+ +D ++ V G H DI
Sbjct: 516 TNEVFHAR---LPGRP---DDYLRTGDLGFILNGELFVSGRLKD-VIIVHGVNHYPHDIE 568
Query: 294 ATVLAVEPMKFIYRGRIAVFSVRVLRDERICIVAE-QRPDCGEEESFQWMSRVLQAVDSI 352
+TV +P I RG FS+ +E + V E R D + F ++ +++
Sbjct: 569 STVDHCDPA--IRRGCGIAFSIPAGSEEGLVFVQEITRADLARADHF--FEQIRRSIYEH 624
Query: 353 HQVGIYCLALVQPNFLPKTPLGGIHLSECKRRFLEGTL 390
H + +AL++ +PKT G + C+ FLE L
Sbjct: 625 HGLRAASIALIESGSIPKTTSGKLARRPCRAFFLEKRL 662
>UniRef50_Q9I157 Cluster: PvdL; n=23; root|Rep: PvdL - Pseudomonas
aeruginosa
Length = 4342
Score = 105 bits (253), Expect = 5e-21
Identities = 114/455 (25%), Positives = 181/455 (39%), Gaps = 26/455 (5%)
Query: 457 QILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVALI 516
Q LR RA + + L VL+ +L +A I L + GD L+
Sbjct: 13 QALRRRAVQEPERLALRFLAEDDGEGVVLSYRDLDLRARSIAAAL--QAHAQLGDRAVLL 70
Query: 517 FPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKL 576
FP G D + AF+GCLY G + V PP H + +I D ++ LVL+ + +
Sbjct: 71 FPSGPDYVAAFFGCLYAGVIAVPAYPPESARRHHQERLLSIIAD-AEPRLVLTTADLREP 129
Query: 577 LRSKEASNVLDSKAWPMTLDTDDMPKKKLPIMYRAPT-AEMLAYLDFSVSTTGMLAGIKM 635
L A L + P L D + E +A+L ++ +T + G+++
Sbjct: 130 LLQMNAQ--LSAANAPQLLCVDQLDPAVAEAWDEPQVRPEHIAFLQYTSGSTALPKGVQV 187
Query: 636 SHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIPPSEVEV 695
SH + + ++ + I L Y +G L I+SG +L+ P
Sbjct: 188 SHGNLVANEVLIRRGFGIGADDVIVSWLPLYHDMGLIGGLLQPIFSGVPCVLMSPRYFLE 247
Query: 696 NPALWLSAVSQYKVRDTFCSYGVMELCTKGLG-SSVNQLKSKGINLACVRTCVVVAEERP 754
P WL A+SQY + LC++ + S++ +L G +A E
Sbjct: 248 RPVRWLEAISQYGGTVSGGPDFAYRLCSERVAESALQRLDLSGWRVA------FSGSEPI 301
Query: 755 RINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPSTVYVDLRALRNDRVS 814
R + F++ F+A + +G G + VD AL +R++
Sbjct: 302 RQDSLERFAEKFAASRFDASSFFACYGLAEATLFVTGGQRGQGIPALAVDGEALARNRIA 361
Query: 815 LVERGSPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNASGYFTIYGD 874
E GS LM G+ P V+ + + GD ++GEIW P A GY+
Sbjct: 362 EGE-GS----VLMCCGRSQPEHAVLIVDAASGEVLGDDNVGEIWAAGPSIAHGYWR--NP 414
Query: 875 ESDYADHFSAQLVTGNTGEVYARTGYLGFLRRTEI 909
E+ SA+ G + RTG LGFLR E+
Sbjct: 415 EA------SAKAFVERDGRTWLRTGDLGFLRDGEL 443
Score = 58.0 bits (134), Expect = 1e-06
Identities = 84/376 (22%), Positives = 144/376 (38%), Gaps = 29/376 (7%)
Query: 20 MVCVLDFKRETGLWHAVLASVLNGMHVIFIPYALMKVSPASWMHMITKHRASIAIVKSRD 79
+V L + GL +L + +G+ + + P W+ I+++ +++ D
Sbjct: 211 IVSWLPLYHDMGLIGGLLQPIFSGVPCVLMSPRYFLERPVRWLEAISQYGGTVS--GGPD 268
Query: 80 LHWGLLATRDHKE----ISLSSLRMLLVADGANPWSLSSCDQFLSVFQSKGVRGDAICPC 135
+ L + R + + LS R+ G+ P S ++F F + R DA
Sbjct: 269 FAYRLCSERVAESALQRLDLSGWRVAF--SGSEPIRQDSLERFAEKFAAS--RFDASSFF 324
Query: 136 ACSSESMTVCIXXXXXXXXXXXXXVLSMSGLSYGVVRVDAENSLTSLTLQDCGQVMPSCV 195
AC + + L+ + + E S+ L CG+ P
Sbjct: 325 ACYGLAEATLFVTGGQRGQGIPALAVDGEALARNRI-AEGEGSV----LMCCGRSQPEHA 379
Query: 196 IVVVKMEGPAYLCKTDEVGEICVLSGATGSGYWGLPGLTNTVFRVRPLDSDGEPIGEEHY 255
+++V L D VGEI + GYW P + F ++ DG +
Sbjct: 380 VLIVDAASGEVL-GDDNVGEIWAAGPSIAHGYWRNPEASAKAF----VERDGRT-----W 429
Query: 256 VRSXXXXXXXXXXXXXXXXSRDGLMTVTGRKHNMDDIIATVLAVEPMKFIYRGRIAVFSV 315
+R+ +D ++ V G DI TV + P +GR+A F+V
Sbjct: 430 LRTGDLGFLRDGELFVTGRLKD-MLIVRGHNLYPQDIERTVESEVPS--ARKGRVAAFAV 486
Query: 316 RVLRDERICIVAE-QRPDCGEEESFQWMSRVLQAVDSIHQVGIYCLALVQPNFLPKTPLG 374
V +E I I AE R + + + + QAV +Q +AL+ P LPKT G
Sbjct: 487 TVDGEEGIGIAAEIGRGVQKSVPAQELIDSIRQAVAEAYQEAPKVVALLNPGALPKTSSG 546
Query: 375 GIHLSECKRRFLEGTL 390
+ S C+ R +G+L
Sbjct: 547 KLQRSACRLRLEDGSL 562
Score = 41.9 bits (94), Expect = 0.090
Identities = 41/157 (26%), Positives = 75/157 (47%), Gaps = 15/157 (9%)
Query: 488 AELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQN 547
AEL+++A R+G+ L G V VAL+ GLDL+ G GA + + P HP
Sbjct: 3742 AELNRRANRLGHALRAAG-VGIDQPVALLAERGLDLLGMIVGSFKAGAGYLPLDPGHPTQ 3800
Query: 548 LHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPK----K 603
T IV++S+ +++ Q+ + ++ + L P L D++ + +
Sbjct: 3801 RLT------RIVELSRTLVLVCTQACRE--QALALFDELGCVDRPRLLVWDEIQQGEGAE 3852
Query: 604 KLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAV 640
P +Y P + LAY+ ++ +TG+ G+ + A +
Sbjct: 3853 HDPQVYSGP--QNLAYVIYTSGSTGLPKGVMVEQAGM 3887
Score = 36.7 bits (81), Expect = 3.4
Identities = 36/169 (21%), Positives = 70/169 (41%), Gaps = 12/169 (7%)
Query: 483 KVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRP 542
+ L+ AEL ++ R+ +L G V V L L+++ L G V + P
Sbjct: 2210 QTLSYAELDARSNRLARVLRSHG-VGPEVRVGLALERSLEMVVGLLAILKAGGAYVPLDP 2268
Query: 543 PHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPK 602
+P L ++ +++ S L+LS+ ++ + L A W + D +
Sbjct: 2269 EYP------LERLQYMIEDSGVRLLLSHAALFEALGELPAGVA----RWCLEEDGPALDA 2318
Query: 603 KKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIAC 651
+ + + AYL ++ +TG G+ +SH + C ++ I C
Sbjct: 2319 EDPAPLAALSGPQHQAYLIYTSGSTGKPKGVAVSHGEIAMHCAAV-IEC 2366
Score = 36.3 bits (80), Expect = 4.5
Identities = 54/225 (24%), Positives = 92/225 (40%), Gaps = 22/225 (9%)
Query: 488 AELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQN 547
AELH +A R+ + L +KG V VA+ L+ + G V + P +P
Sbjct: 1157 AELHARANRLAHYLRDKG-VGPDVRVAICAERSPQLLVGLLAIVKAGGAYVPLDPDYPSE 1215
Query: 548 LHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASN--VLDSKAWPMTLDTDDMPKKKL 605
M+ D S L+L+ + + L E LDS L D+ P +
Sbjct: 1216 -----RLAYMLAD-SGVELLLTQAHLFERLPGAEGVTPICLDS------LKLDNWP-SQA 1262
Query: 606 PIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIALCLDP 665
P ++ + LAY+ ++ +TG G+ +HAA+ + M+ L + + P
Sbjct: 1263 PGLHL--HGDNLAYVIYTSGSTGQPKGVGNTHAALAERLQWMQATYTL-DGDDVLMQKAP 1319
Query: 666 YCGLGFALW-CLSSIYSGHHSILIPPSEVEVNPALWLSAVSQYKV 709
++W C + +G +L P E +PA + V Q+ V
Sbjct: 1320 -VSFDVSVWECFWPLVTGCRLVLAAPGE-HRDPARLVELVRQFGV 1362
>UniRef50_Q212V5 Cluster: Amino acid adenylation; n=2; cellular
organisms|Rep: Amino acid adenylation - Rhodopseudomonas
palustris (strain BisB18)
Length = 4165
Score = 105 bits (252), Expect = 6e-21
Identities = 94/398 (23%), Positives = 165/398 (41%), Gaps = 15/398 (3%)
Query: 510 GDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLS 569
G L+ P G D + A CLY GAV V + P + L V I AT +L+
Sbjct: 68 GGRALLLLPSGHDYVVALLACLYAGAVAVPVNLPGASRVARVLGRVEHISRDCGATAILT 127
Query: 570 NQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKKLPIMYRAPTAEMLAYLDFSVSTTGM 629
+++ +S+EA + + DD + Y +P+ +A++ ++ +T
Sbjct: 128 TRAIAD--QSREALTSFVAAHRLRLILIDDAKSGRAWSGY-SPSETDIAFIQYTSGSTAE 184
Query: 630 LAGIKMSHAAVTSLCRSMKIACELYPSRH--IALCLDPYCGLGFALWCLSSIYSGHHSIL 687
G+ H + S ++ C L+P +A L + +G + L+ + G +
Sbjct: 185 PKGVINRHDTLISNVSFLR--CLLWPKDAPVVASWLPLFHDMGLIMGVLAPLALGGRVVY 242
Query: 688 IPPSEVEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCV 747
+ P +P +WL ++ + C ++ C + + + + ++L+CV + V
Sbjct: 243 MAPGAFVSDPLMWLELAARERAAVLPCPAFALDACVEHYDAD----RLRDLDLSCVESLV 298
Query: 748 VVAEERPRINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPSTVYVDLRA 807
AE + +F L+S GL A+ S+G I + P V VD +
Sbjct: 299 PAAEP-VHLRQVRAFFDLYSRHGLHWGAIRPSYGLAEATLIASGSSHDGGPVAVSVDAAS 357
Query: 808 LRNDRVSLVERGSPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNASG 867
+ +V G+P S + +G G + +PET+ +GEIW+ A+G
Sbjct: 358 IARGTALVVTDGAPDSRVYLSNGADFGGQDLRIVDPETRRTKPAGDVGEIWISGAAIAAG 417
Query: 868 YF-TIYGDESDYADHFSAQLVTGNTGEVYARTGYLGFL 904
Y+ E +A H S + T Y RTG LGFL
Sbjct: 418 YWGRSDATEETFAAHLSDDGASDATN--YLRTGDLGFL 453
Score = 54.0 bits (124), Expect = 2e-05
Identities = 77/368 (20%), Positives = 141/368 (38%), Gaps = 20/368 (5%)
Query: 29 ETGLWHAVLASVLNGMHVIFIPYALMKVSPASWMHMITKHRASIAIVKSRDL-----HWG 83
+ GL VLA + G V+++ P W+ + + RA++ + L H+
Sbjct: 223 DMGLIMGVLAPLALGGRVVYMAPGAFVSDPLMWLELAARERAAVLPCPAFALDACVEHYD 282
Query: 84 LLATRDHKEISLSSLRMLLVADGANPWSLSSCDQFLSVFQSKGVRGDAICPCACSSESMT 143
RD + LS + L+ A A P L F ++ G+ AI P +E+
Sbjct: 283 ADRLRD---LDLSCVESLVPA--AEPVHLRQVRAFFDLYSRHGLHWGAIRPSYGLAEA-- 335
Query: 144 VCIXXXXXXXXXXXXXVLSMSGLSYGVVRVDAENSLTSLTLQDCGQVMPSCVIVVVKMEG 203
I + + ++ G V + + S G + +V E
Sbjct: 336 TLIASGSSHDGGPVAVSVDAASIARGTALVVTDGAPDSRVYLSNGADFGGQDLRIVDPE- 394
Query: 204 PAYLCKTDEVGEICVLSGATGSGYWGLPGLTNTVFRVRPLDSDGEPIGEEHYVRSXXXXX 263
+VGEI + A +GYWG T F L DG +Y+R+
Sbjct: 395 TRRTKPAGDVGEIWISGAAIAAGYWGRSDATEETFAAH-LSDDGAS-DATNYLRTGDLGF 452
Query: 264 XXXXXXXXXXXSRDGLMTVTGRKHNMDDIIATVLAVEPMKFIYRGRIAVFSVRVLRD-ER 322
S+D +M G+ H +DI A++ + I G A F++ + ER
Sbjct: 453 LHGGHLYITGRSKD-VMIFRGQCHYPNDIEASLANLH--DDIIAGGAAAFAIPGDQGVER 509
Query: 323 ICIVAEQRPDCGEEESFQWMSRVLQAVDSIHQVGIYCLALVQPNFLPKTPLGGIHLSECK 382
+ +V E R + ++ + + + + H + + + L++ L +T G + +E +
Sbjct: 510 LVVVQEVRRH-SDLDAAALEASIRETIAREHGLAAHDVVLIRRGTLKRTTSGKVRRAEMR 568
Query: 383 RRFLEGTL 390
R ++ G L
Sbjct: 569 RLYISGGL 576
>UniRef50_Q2T8M1 Cluster: AMP-binding domain protein; n=7;
pseudomallei group|Rep: AMP-binding domain protein -
Burkholderia thailandensis (strain E264 / ATCC 700388 /
DSM 13276 /CIP 106301)
Length = 620
Score = 105 bits (251), Expect = 9e-21
Identities = 114/486 (23%), Positives = 192/486 (39%), Gaps = 30/486 (6%)
Query: 440 MGYTDDSDAARKYQFISQILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGN 499
M + D+ A + +++R+RA D ++T + + LTCA+L ++A +
Sbjct: 1 MTHPPDTTTADAFADFVELMRYRAAHQPDLPVYTFVAGGDRDERHLTCAQLDRRASAVAA 60
Query: 500 LLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIV 559
L E R G+ V L+F PG+D I A +G +Y G V V P P TL + IV
Sbjct: 61 ALSEIAR--PGERVLLLFAPGIDYIAALFGSMYAGVVAVPAYPVEPAQPERTLRRLLGIV 118
Query: 560 DVSKATLVLSNQSV-IKLLRSKEASNVLDSKAWPMTLDTDDMPKKKLPIMYRAPTAEMLA 618
VLS +V + R + S VL W + +D RA +
Sbjct: 119 ADCAPVAVLSTTAVRDDMSRVETGSPVLRGLRW-IEIDALAPGDDAAHGAPRAADPRVPV 177
Query: 619 YLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSS 678
YL ++ +TG G+ +SH + + E S + L PY +G L
Sbjct: 178 YLQYTSGSTGAPKGVMISHQNLLHNSALIARRFEHGASSRGVIWLPPYHDMGLIGGILQP 237
Query: 679 IYSGHHSILIPPSEVEVNPALWLSAVSQYKVRDT-FCSYGVMELCTKGLG-SSVNQLKSK 736
+Y G L+ + +P WL A+ + + + ++ L T + + ++L +
Sbjct: 238 LYVGFPVTLMSHVDFLKHPLRWLRAIGERRATTSGGPNFAYQMLATMRIADADFDKLDLR 297
Query: 737 GINLACVRTCVVVAEERPRINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSP 796
++A V E R ++F++ F+ G A +G + G S
Sbjct: 298 SWDVA------FVGAEPIRPATLHAFAQRFARCGFDAHAFYPCYGLAEHTLFMTGGLKSQ 351
Query: 797 EPSTVYV--DLRALR-----------NDRVSLVERGSPHSLCLMESGKLLPGVKVITANP 843
P + D + R ND + + + G V+ +P
Sbjct: 352 PPVVAHAPGDAQQPRASDRADDANDANDADQAGDGRQASARAAIGCGDAASDSLVLIVDP 411
Query: 844 ETKGQCGDSHLGEIWVQSPHNASGYFTIYGDESDYADHFSAQLVTGNTGEVYARTGYLGF 903
+T+ C D +GEIW Q P A GY + + + F A+L G G + RTG G+
Sbjct: 412 DTRVPCDDGRVGEIWAQGPSVALGY---WNNRALSKQTFEAEL-PGYEGR-FLRTGDYGY 466
Query: 904 LRRTEI 909
+E+
Sbjct: 467 RSGSEV 472
Score = 53.2 bits (122), Expect = 4e-05
Identities = 49/214 (22%), Positives = 82/214 (38%), Gaps = 19/214 (8%)
Query: 187 CGQVMPSCVIVVVKMEGPAYLCKTDEVGEICVLSGATGSGYWGLPGLTNTVFRVRPLDSD 246
CG ++++V + C VGEI + GYW L+ F
Sbjct: 397 CGDAASDSLVLIVDPD-TRVPCDDGRVGEIWAQGPSVALGYWNNRALSKQTFEAEL---- 451
Query: 247 GEPIGEEHYVRSXXXXXXXXXXXXXXXXSRDGLMTVTGRKHNMDDIIATVLAVEPMKFIY 306
P E ++R+ +D +M + G H D+ AT+ A++ F
Sbjct: 452 --PGYEGRFLRTGDYGYRSGSEVFVTGRLKD-MMLIRGANHYPHDVEATIEALDAELF-R 507
Query: 307 RGRIAVFSVRVLRDERICIVAEQRP-------DCGEEESFQ---WMSRVLQAVDSIHQVG 356
G AVF++ ++ +V E R D G E R+ QA++ H +
Sbjct: 508 PGGCAVFALDTGAAPQVTVVRELRARYLKAFGDGGHEAGHTPDALFGRLRQAINRHHGIA 567
Query: 357 IYCLALVQPNFLPKTPLGGIHLSECKRRFLEGTL 390
++ + P+ +PKT G + C+ FL TL
Sbjct: 568 VHHIVFTSPSAIPKTTSGKVQRHACRELFLNDTL 601
>UniRef50_Q93HG9 Cluster: Non-ribosomal peptide synthetase; n=1;
Streptomyces avermitilis|Rep: Non-ribosomal peptide
synthetase - Streptomyces avermitilis
Length = 574
Score = 104 bits (249), Expect = 1e-20
Identities = 108/439 (24%), Positives = 182/439 (41%), Gaps = 42/439 (9%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPH 544
++ L +++ + + L E+G G L++PPGL+ IC + GCL G V V PP
Sbjct: 37 ISYGRLAERSRAVASWLQERGLA--GSRAMLLYPPGLEFICGYLGCLSAGVVAVPGVPPQ 94
Query: 545 PQNL-HTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKK 603
++ H L ++ ++ + A ++L + VI L + + L A + T+D+P
Sbjct: 95 GRSQNHRALTRMKRLIADADAKVILGGREVIAALGT--MAEHLPELAEITCVATEDIPDA 152
Query: 604 KLPIMYRAP--TAEMLAYLDFSVSTTGMLAGIKMSHA-------AVTSLCRSMKIACELY 654
+R P TA+ +A+L ++ +T G+ ++H +T Y
Sbjct: 153 AAG-SWREPDLTADSVAFLQYTSGSTSAPRGVMVTHGNLLDNERVITERMGHTPDTIAEY 211
Query: 655 PSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIPPSEVEVNPALWLSAVSQYKVRDTFC 714
L Y +G L+++Y G + L P P WL+A+S Y+ +
Sbjct: 212 DHELFVSWLPVYHDMGLIGPVLNTVYLGATATLFSPLHFLQQPQRWLTALSHYRPHTSGG 271
Query: 715 SYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVVAEERPRINLTNSFSKLFSALGLSPR 774
ELC K + G++L+ + AE R F++ F G
Sbjct: 272 PNFAYELCLKQATPDL----LDGLDLSRWKVAFNGAEP-VRAATLRRFTETFGTAGFRRE 326
Query: 775 AVSTSFGCRVNIAICLQGASSPEPSTVYVDLRALRNDRVSLVERGSPHS----LCLMESG 830
A+ +G + + G S P T+ + E G PH+ + SG
Sbjct: 327 ALYPCYGL-AEATLMVTGGSVAAPPTL-----------IEAPETG-PHAGAADAAAVGSG 373
Query: 831 KLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNASGYFTIYGDESDYADHFSAQLVTGN 890
+ PGV ++ A+PE + + D +GEIWV A GY+ + A S + N
Sbjct: 374 RPGPGVTLVIADPERQQELPDGEVGEIWVLGASVAKGYW-----RNTLATRESFRATLKN 428
Query: 891 TGEVYARTGYLGFLRRTEI 909
+ RTG LGFLR E+
Sbjct: 429 REGRFLRTGDLGFLRDGEL 447
Score = 63.7 bits (148), Expect = 3e-08
Identities = 87/375 (23%), Positives = 140/375 (37%), Gaps = 25/375 (6%)
Query: 18 EHMVCVLDFKRETGLWHAVLASV-LNGMHVIFIPYALMKVSPASWMHMITKHRASIAIVK 76
E V L + GL VL +V L +F P ++ P W+ ++ +R +
Sbjct: 214 ELFVSWLPVYHDMGLIGPVLNTVYLGATATLFSPLHFLQ-QPQRWLTALSHYRPHTSGGP 272
Query: 77 SRDLHWGLLATRDHKEISLSSLRMLLVADGANPWSLSSCDQFLSVFQSKGVRGDAICPCA 136
+ L L R + +GA P ++ +F F + G R +A+ PC
Sbjct: 273 NFAYELCLKQATPDLLDGLDLSRWKVAFNGAEPVRAATLRRFTETFGTAGFRREALYPCY 332
Query: 137 CSSESMTVCIXXXXXXXXXXXXXVLSMSGLSYGVVRVDAENSLTSLTLQDCGQVMPSCVI 196
+E+ T+ + +G G A S G+ P +
Sbjct: 333 GLAEA-TLMVTGGSVAAPPTLIEAPE-TGPHAGAADAAAVGS---------GRPGPGVTL 381
Query: 197 VVVKMEGPAYLCKTDEVGEICVLSGATGSGYWGLPGLTNTVFRVRPLDSDGEPIGEEHYV 256
V+ E L EVGEI VL + GYW T FR + +G ++
Sbjct: 382 VIADPERQQEL-PDGEVGEIWVLGASVAKGYWRNTLATRESFRATLKNREGR------FL 434
Query: 257 RSXXXXXXXXXXXXXXXXSRDGLMTVTGRKHNMDDIIATVLAVEPMKFIYRGRIAVFSVR 316
R+ +D L+ + GR H D+ + P + G A FSV
Sbjct: 435 RTGDLGFLRDGELFVTGRLKD-LIVIDGRNHYPQDLELSAEMSHPA--LRPGCTATFSVD 491
Query: 317 V-LRDERICIVAEQRPDCGEEESFQWMSRVLQAVDSIHQVGIYCLALVQPNFLPKTPLGG 375
+ E+ IVAE P+ +E + R+ A+ H + + + LV P +PKT G
Sbjct: 492 GGVEGEQPVIVAEAAPEAADEFE-KITDRIRSAIGEAHGLSVRDVVLVHPGTIPKTSSGK 550
Query: 376 IHLSECKRRFLEGTL 390
I + +L+GTL
Sbjct: 551 IQRRASRTAYLDGTL 565
>UniRef50_A7Q867 Cluster: Chromosome undetermined scaffold_62, whole
genome shotgun sequence; n=3; Vitis vinifera|Rep:
Chromosome undetermined scaffold_62, whole genome
shotgun sequence - Vitis vinifera (Grape)
Length = 632
Score = 103 bits (248), Expect = 2e-20
Identities = 107/438 (24%), Positives = 178/438 (40%), Gaps = 36/438 (8%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPH 544
LT A+L+ A+ I +L R+ GD V ++ PGL+L+ +GC G + V I PPH
Sbjct: 44 LTYAQLNSSAQSISAKILH--RLKRGDTVVILCSPGLELVEIIFGCQRAGLLSVPIFPPH 101
Query: 545 PQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMT-----LDTDD 599
P + ++ +K ++ I ++ +S V D + + + TDD
Sbjct: 102 PSFTKEDHYHLVRVLSRTKPKAAIAQHGFIAAVKRYVSSPVSDKRLCELLQGVRWISTDD 161
Query: 600 MPKKKL------PIMYRAPTAEMLAYLDFSVSTTGM-LAGIKMSHAAVTSLCRSMKIACE 652
+ K + Y A+ + + F+ TG+ + ++ A R+ + A
Sbjct: 162 VKDGKEGNSSSGSLPYHGCKADEMYLVQFTSGATGIPKPPVLVTAGAAAHNVRTARKAYH 221
Query: 653 LYPSRHIALCLDPY--CGLGFALWCLSSIYSGHHSILIPPSEVEVNPALWLSAVSQYKVR 710
L+P+ I L Y CGL ++ L +I SG +L P P LWL +S+YK
Sbjct: 222 LHPNSVIVSWLPQYHDCGL---MFLLLTIVSGATCVLTSPIAFVNRPRLWLELISEYKAT 278
Query: 711 DTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVVAEERPRINLTNSFSKLFSALG 770
T + L K G L INL ++ +++ E R + F F G
Sbjct: 279 CTPVPSFALPLVVKRGGIDKGTLP---INLWSLKNLIIINEPIYR-DSVEEFVNAFLPFG 334
Query: 771 LSPRAVSTSFGCRVNIAICLQGASSPEPSTVYVDLRALRNDRVSLVERGSPHSLCLMESG 830
L+P +S S+G N + S+ + ++ + L+ S C+ E
Sbjct: 335 LNPACISPSYGLAENCTFVSTAWRNNGGSSSFPNIPSYN----KLLPSARLASECIDEE- 389
Query: 831 KLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNASGYFTIYGDESDYADHFSAQLVTGN 890
+ ++ N ET+ D GEIWV S NASGY D + ++
Sbjct: 390 ----EMDILVVNEETQEPVEDGIEGEIWVSSSSNASGYL----DHPSLTRYVFLGRLSNK 441
Query: 891 TGEVYARTGYLGFLRRTE 908
+ RTG G ++ E
Sbjct: 442 VSSCFVRTGDRGIVKGEE 459
>UniRef50_A6FHW6 Cluster: Amino acid adenylation; n=1; Moritella sp.
PE36|Rep: Amino acid adenylation - Moritella sp. PE36
Length = 695
Score = 103 bits (247), Expect = 3e-20
Identities = 103/425 (24%), Positives = 181/425 (42%), Gaps = 27/425 (6%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPH 544
LT +++++ I L +K + G+ LI+ + I AF GCL G + V + P
Sbjct: 40 LTYSDVYESMYNIAQNLGDKA--SKGERALLIYEDSENFITAFLGCLAAGVIAVPLSVPR 97
Query: 545 PQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKK 604
Q + + IV S ++L++ + K L ++ + +TD
Sbjct: 98 TQEMKNI---INYIVSNSDSSLIMCDSKTRKKLEGVLTNSRISY------FETDGGLSSS 148
Query: 605 LPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIALC-- 662
I + +A+L ++ +TG G+ ++HA + + ++I + H C
Sbjct: 149 SKIRTHTILPDDIAFLQYTSGSTGEPKGVMVTHANIMNNLDVIRIL--FGHTTHSVGCSW 206
Query: 663 LDPYCGLGFALWCLSSIYSGHHSILIPPSEVEVNPALWLSAVSQYKVRDTFCSYGVMELC 722
L Y +G L ++ G +L+ S P WLS +S+Y V + +LC
Sbjct: 207 LPHYHDMGLLGGILQPLFVGFPVVLMAASRFIRKPFYWLSIISEYGVTTSGGPNFAYDLC 266
Query: 723 TKGLGSSVNQLKSKGINLACVRTCVVVAEERPRINLT-NSFSKLFSALGLSPRAVSTSFG 781
K V + + ++L+ R CV P +N T +F++ F G SP + +G
Sbjct: 267 IK----HVKEADVRSLDLS--RWCVAFNGAEPVVNATLENFNEKFQVAGFSPASHYPCYG 320
Query: 782 CRVNIAICLQGASSPEPSTVYVDLRALRNDRVSLVERGSPHSLCLMESGKLLPGVKVITA 841
+ S+ +T+ V +L V V+ + +S L+ +G PG ++I
Sbjct: 321 MAETTLLVSGLGSNTVNNTLTVCRPSLSAGIVLPVDDHNDNSRTLVSNGICAPGHEIIIV 380
Query: 842 NPETKGQCGDSHLGEIWVQSPHNASGYFTIYGDESDYADHFSAQLVTGNT--GEVYARTG 899
+ ET + + ++GEIWV P SGY + + + F A T G+ Y RTG
Sbjct: 381 SEETGKKVKEGNVGEIWVTGPSVTSGY---WKRPALTNNRFKATTFGNETDSGQRYYRTG 437
Query: 900 YLGFL 904
LGFL
Sbjct: 438 DLGFL 442
Score = 62.1 bits (144), Expect = 8e-08
Identities = 76/349 (21%), Positives = 141/349 (40%), Gaps = 9/349 (2%)
Query: 29 ETGLWHAVLASVLNGMHVIFIPYALMKVSPASWMHMITKHRASIAIVKSRDLHWGLLATR 88
+ GL +L + G V+ + + P W+ +I+++ + + + + +
Sbjct: 212 DMGLLGGILQPLFVGFPVVLMAASRFIRKPFYWLSIISEYGVTTSGGPNFAYDLCIKHVK 271
Query: 89 DHKEISLSSLRMLLVADGANPWSLSSCDQFLSVFQSKGVRGDAICPCACSSESMTVCIXX 148
+ SL R + +GA P ++ + F FQ G + PC +E+ T+ +
Sbjct: 272 EADVRSLDLSRWCVAFNGAEPVVNATLENFNEKFQVAGFSPASHYPCYGMAET-TLLVSG 330
Query: 149 XXXXXXXXXXXVLSMSGLSYGVVRVDAENSLTSLTLQDCGQVMPSCVIVVVKMEGPAYLC 208
V S LS G+V +++ S TL G P I++V E +
Sbjct: 331 LGSNTVNNTLTVCRPS-LSAGIVLPVDDHNDNSRTLVSNGICAPGHEIIIVSEETGKKV- 388
Query: 209 KTDEVGEICVLSGATGSGYWGLPGLTNTVFRVRPLDSDGEPIGEEHYVRSXXXXXXXXXX 268
K VGEI V + SGYW P LTN F+ ++ + G+ +Y R+
Sbjct: 389 KEGNVGEIWVTGPSVTSGYWKRPALTNNRFKATTFGNETDS-GQRYY-RTGDLGFLYSKQ 446
Query: 269 XXXXXXSRDGLMTVTGRKHNMDDIIATVLAVEPMKFIYRGRIAVFSVRVLRDERICIVAE 328
D ++ V GR + +DI + + M +Y + VF V E + ++ E
Sbjct: 447 LYVCGRQLDKII-VRGRNYFAEDI--EYVLTKCMAELYITAMVVFGVTNGTSENLILLVE 503
Query: 329 -QRPDCGEEESFQWMSRVLQAVDSIHQVGIYCLALVQPNFLPKTPLGGI 376
R + ++ + ++ A+ + +Y + +QP L KT G +
Sbjct: 504 VPRNRSIDFDACKVCIQLRSAIRRHFSLELYDIVFLQPRSLLKTTSGKV 552
>UniRef50_A4C5W5 Cluster: Beta-ketoacyl synthase; n=1;
Pseudoalteromonas tunicata D2|Rep: Beta-ketoacyl
synthase - Pseudoalteromonas tunicata D2
Length = 674
Score = 103 bits (247), Expect = 3e-20
Identities = 105/455 (23%), Positives = 185/455 (40%), Gaps = 22/455 (4%)
Query: 458 ILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERI--GNLLLEKGRVNTGDHVAL 515
+L + A++ +F ++ G L ++ RI G L K N D +
Sbjct: 11 LLAFDARNKPSQEVFRFVSDNGESEASYDYQTLSQEISRIAIGLQALIKTSHNQ-DQALI 69
Query: 516 IFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIK 575
+ P G+ + AFYGC+ + V PP Q L I D+ +V++N+ ++
Sbjct: 70 VLPQGVQFVTAFYGCMAANVIAVPSFPPKSQLQIERLQFA--ITDLGNP-IVITNRDILP 126
Query: 576 LLRSKEASNVLDSKAWPMTLDTDDMPKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKM 635
L+ A LDS W + D + + P+ +A L +S TTG G+ +
Sbjct: 127 KLQEHIA---LDSVRWLLIEDLASVIAQ--PLSDFRTHEHSIALLQYSSGTTGKPKGVII 181
Query: 636 SHAAVTSLCRSMKIAC-ELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIPPSEVE 694
++ + ++ + + L L P+ +G + +Y+G+ ++L+P
Sbjct: 182 TNQNIMENSELIRQSFGHKEDHTRMMLWLPPHHDMGLVGGVMQGVYTGYPTLLMPTDLFL 241
Query: 695 VNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVVAEERP 754
+ WL AVS Y+ T EL K + S + ++L+ + AE
Sbjct: 242 RSQYRWLKAVSDYRATTTGAPNFAYELAVKNIRES----RLAELDLSSLENLFCGAEPIN 297
Query: 755 RINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPSTVYVDLRALRNDRVS 814
++ N F F+ GL P A +G + + + +D L++ V
Sbjct: 298 SHSI-NQFLDKFAPCGLKPEAFLPCYGMAEATLMVSGKPHGQQYKQLCIDEPLLKHGMVK 356
Query: 815 LVERGSPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNASGYFTIYGD 874
+ + HSL L+ SG + ++ NPET + +GEIW+Q + GY + D
Sbjct: 357 PLNTPNAHSLWLVSSGVVHSSLQARIVNPETGTEVAQGQVGEIWLQGSSISPGY---WQD 413
Query: 875 ESDYADHFSAQLVTGNTGEVYARTGYLGFLRRTEI 909
A +F L E + RTG LGF + E+
Sbjct: 414 AERTAINFGLPL--AGYEETFHRTGDLGFYHQDEL 446
Score = 50.0 bits (114), Expect = 3e-04
Identities = 49/202 (24%), Positives = 82/202 (40%), Gaps = 7/202 (3%)
Query: 29 ETGLWHAVLASVLNGMHVIFIPYALMKVSPASWMHMITKHRASIAIVKSRDLHWGLLATR 88
+ GL V+ V G + +P L S W+ ++ +RA+ + + R
Sbjct: 215 DMGLVGGVMQGVYTGYPTLLMPTDLFLRSQYRWLKAVSDYRATTTGAPNFAYELAVKNIR 274
Query: 89 DHK--EISLSSLRMLLVADGANPWSLSSCDQFLSVFQSKGVRGDAICPCACSSESMTVCI 146
+ + E+ LSSL L GA P + S +QFL F G++ +A PC +E+ +
Sbjct: 275 ESRLAELDLSSLENLFC--GAEPINSHSINQFLDKFAPCGLKPEAFLPCYGMAEA--TLM 330
Query: 147 XXXXXXXXXXXXXVLSMSGLSYGVVRVDAENSLTSLTLQDCGQVMPSCVIVVVKMEGPAY 206
+ L +G+V+ + SL L G V S +V E
Sbjct: 331 VSGKPHGQQYKQLCIDEPLLKHGMVKPLNTPNAHSLWLVSSGVVHSSLQARIVNPETGTE 390
Query: 207 LCKTDEVGEICVLSGATGSGYW 228
+ + +VGEI + + GYW
Sbjct: 391 VAQ-GQVGEIWLQGSSISPGYW 411
>UniRef50_A6P633 Cluster: Acyl-ACP synthetase; n=1; Microcystis
aeruginosa|Rep: Acyl-ACP synthetase - Microcystis
aeruginosa
Length = 628
Score = 103 bits (246), Expect = 3e-20
Identities = 87/365 (23%), Positives = 152/365 (41%), Gaps = 19/365 (5%)
Query: 458 ILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIF 517
+L RA+ T + + L + + + LT +L KA I L + G TGD V L++
Sbjct: 12 LLAQRAKETPNQTAYLFLKDEETIIERLTYQDLADKALTIAAGLQQLGA--TGDRVLLLY 69
Query: 518 PPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLL 577
PPGL+ I A +GC G + V PP P +L ++ IV S+A L LS+ +
Sbjct: 70 PPGLEFIEALFGCFAAGMIAVPAYPPRPNQ---SLKRLQSIVKSSQAKLSLSSTKIQSNQ 126
Query: 578 RSKEASNVLDSKAWPMTLDTDDMPKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSH 637
+K L + K L + T + L L ++ +TG G+ +SH
Sbjct: 127 DNKNYLGDLTEIDCRQLTQFNSQDWKPLKL-----TPDTLGILQYTSGSTGNPKGVMVSH 181
Query: 638 AAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIPPSEVEVNP 697
+ S C + P+ + L + LG L+ ++ G S L+ P + P
Sbjct: 182 GNLISNCEDLSRGWHQEPNSKLVSWLPTFHDLGLVYGILTPLWRGFPSYLLSPLSFLLKP 241
Query: 698 ALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSK-GINLACVRTCVVVAEERP-R 755
WL +S+Y+ + +LC V + K K G NL + + +P +
Sbjct: 242 ITWLKIISRYQATHSAAPNFAYDLC-------VRKFKPKDGENLDLTSWRMTLNGAQPVK 294
Query: 756 INLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPSTVYVDLRALRNDRVSL 815
SFS+ F+ G P+ S +G +P + ++ + + ++V +
Sbjct: 295 AETLASFSQTFAPYGFKPQTFSPGYGLAEATLKVAAVRDKDDPLLLIIEKKDFQKNQVKV 354
Query: 816 VERGS 820
V++ +
Sbjct: 355 VKQST 359
Score = 64.1 bits (149), Expect = 2e-08
Identities = 57/213 (26%), Positives = 90/213 (42%), Gaps = 10/213 (4%)
Query: 179 LTSLTLQDCGQVMPSCVIVVVKMEGPAYLCKTDEVGEICVLSGATGSGYWGLPGLTNTVF 238
L + L CGQ I ++ E + +E+GEI V GYW P + F
Sbjct: 400 LKTQILVSCGQSEIDTEIQIINPE-TLMPSQANEIGEIWVRGLTVSQGYWNNPSASELTF 458
Query: 239 RVRPLDSDGEPIGEEHYVRSXXXXXXXXXXXXXXXXSRDGLMTVTGRKHNMDDIIATVLA 298
+ D+ P ++R+ +D L+ + GR H DI +TV
Sbjct: 459 QAYRSDTKEGP-----FLRTGDLGFLYQGQLFVTGRLKD-LIIIEGRNHYPQDIESTVEN 512
Query: 299 VEPMKFIYRGRIAVFSVRVLRDERICIVAE-QRPDCGEEESFQWMSRVLQAVDSIHQVGI 357
+ + + A FSV + +ER+ IVAE +R + + ++ +AV H +
Sbjct: 513 TDLA--LRKEACAAFSVEIKGEERLVIVAEIERSYDRKIDEVALKKKIREAVALEHDIRG 570
Query: 358 YCLALVQPNFLPKTPLGGIHLSECKRRFLEGTL 390
+AL++ N LPKT G I C+ FL G L
Sbjct: 571 DKIALIRHNCLPKTSSGKIQRQLCRSLFLNGEL 603
>UniRef50_A3ZWL3 Cluster: Saframycin Mx1 synthetase B; n=1;
Blastopirellula marina DSM 3645|Rep: Saframycin Mx1
synthetase B - Blastopirellula marina DSM 3645
Length = 1088
Score = 103 bits (246), Expect = 3e-20
Identities = 103/442 (23%), Positives = 180/442 (40%), Gaps = 25/442 (5%)
Query: 464 QSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDL 523
+S D+ FT L + V +L +A+ I + LL+ V GD L++P GLD
Sbjct: 2 ESQGDNAAFTFLKSDDEQISV-NYRDLDSRAQEIAHRLLQV--VEPGDRALLMYPAGLDF 58
Query: 524 ICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEAS 583
I AF GCLY G V V PP + T+ D S L+ ++++ K E +
Sbjct: 59 IEAFLGCLYAGIVAVPAYPPKKNRNAERILTI--AEDCSPRLLLCASET--KRNVEAEIA 114
Query: 584 NVLDSKAWPMTLDTDDMPKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSL 643
+ A T + LP + ++ LA+L ++ +T + G+ ++H + +
Sbjct: 115 RAMPRSAVLATNELSTSRCGSLPQL----RSDQLAFLQYTSGSTAVPKGVMVTHGNIVAN 170
Query: 644 CRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIPPSEVEVNPALWLSA 703
R ++ + + L + +G L+ ++ G S+L+ P+ P WL
Sbjct: 171 ERLIQKYFQFTQDSLVVSWLPMFHDMGLIGGILAPLFVGAPSVLMAPNTFLREPIKWLQT 230
Query: 704 VSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVVAEERPRINLTNSFS 763
V+ + T +LC K + S + K ++L+ + E R FS
Sbjct: 231 VTDFGATATGAPNFAFDLCAKKITSE----QKKSLDLSTL-NITFNGSEPVRAETLQRFS 285
Query: 764 KLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPSTVYVDLRALRNDRVSLVERGSPHS 823
F+ G A +G + G VD L R+ ++G P
Sbjct: 286 AAFADCGFRSEAFFPCYGMAETTLLVSGGPPLAHTEIARVDSAQLVQHRIVDSDQGQP-- 343
Query: 824 LCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNASGYFTIYGDESDYADHFS 883
L+ G++ ++V +P+T + +GEIW+ A GY + ++ + F
Sbjct: 344 --LVSCGQVGSDLEVRIVDPQTFVERKAQEVGEIWLNGDSVAQGY---WHRTNETVEAFQ 398
Query: 884 AQLVTGNTGEVYARTGYLGFLR 905
A+L + + RTG GFLR
Sbjct: 399 AKLAGDDRN--WLRTGDYGFLR 418
Score = 58.8 bits (136), Expect = 7e-07
Identities = 92/428 (21%), Positives = 163/428 (38%), Gaps = 35/428 (8%)
Query: 1 MLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLASVLNGM-HVIFIPYALMKVSPA 59
++A+ R++ +T+ +V L + GL +LA + G V+ P ++ P
Sbjct: 167 IVANERLIQKYFQFTQDSLVVSWLPMFHDMGLIGGILAPLFVGAPSVLMAPNTFLR-EPI 225
Query: 60 SWMHMITKHRASIAIVKSR--DLHWGLLATRDHKEISLSSLRMLLVADGANPWSLSSCDQ 117
W+ +T A+ + DL + + K + LS+L + +G+ P + +
Sbjct: 226 KWLQTVTDFGATATGAPNFAFDLCAKKITSEQKKSLDLSTLNITF--NGSEPVRAETLQR 283
Query: 118 FLSVFQSKGVRGDAICPCACSSESMTVCIXXXXXXXXXXXXXVLSMSGLSYGVVRVDAEN 177
F + F G R +A PC +E+ T+ + V S + + +V D
Sbjct: 284 FSAAFADCGFRSEAFFPCYGMAET-TLLVSGGPPLAHTEIARVDSAQLVQHRIVDSDQGQ 342
Query: 178 SLTSLTLQDCGQVMPSCVIVVVKMEGPAYLCKTDEVGEICVLSGATGSGYWGLPGLTNTV 237
L S CGQV + +V + K EVGEI + + GYW T
Sbjct: 343 PLVS-----CGQVGSDLEVRIVDPQTFVER-KAQEVGEIWLNGDSVAQGYWHRTNETVEA 396
Query: 238 FRVRPLDSDGEPIGEEHYVRSXXXXXXXXXXXXXXXXSRDGLMTVTGRKHNMDDIIATVL 297
F+ + L D + +++R+ +D L+ + GR DI L
Sbjct: 397 FQAK-LAGD-----DRNWLRTGDYGFLRDGQLYVTGRLKD-LIIIRGRNIYPQDI--EEL 447
Query: 298 AVEPMKFIYRGRIAVFSVRVLRDERICIVAEQRPDC----------GEEESFQWMSRVLQ 347
+ + I A FSV +E++ ++A + GE L+
Sbjct: 448 VEQHFEVIEPNSCAAFSVESNGEEKLLVIAAGTREMVRWSNNGGGNGEVVDLHHKIDTLR 507
Query: 348 -AVDSIHQVGIYCLALVQPNFLPKTPLGGIHLSECKRRFLEGTLHP--SNVLMCPHTCVT 404
A+ + +V + L V+P P T G + K+RF G + + P T T
Sbjct: 508 SAILNQFEVALTDLMFVRPTTFPTTSSGKVQRQLAKKRFESGDFEIVFESAVRTPETVET 567
Query: 405 NLPKPREI 412
+L E+
Sbjct: 568 SLSGSAEL 575
>UniRef50_A6G174 Cluster: Non-ribosomal peptide synthase; n=1;
Plesiocystis pacifica SIR-1|Rep: Non-ribosomal peptide
synthase - Plesiocystis pacifica SIR-1
Length = 635
Score = 102 bits (244), Expect = 6e-20
Identities = 105/437 (24%), Positives = 177/437 (40%), Gaps = 21/437 (4%)
Query: 458 ILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIG-NLLLEKGRVNTGDHVALI 516
+L RAQ + ++ G + + LT AE ++A + L ++ TGD V L+
Sbjct: 36 VLHIRAQLHPETPLYQTY-VDGEIRETLTYAEADRRARALAVELRRIHPQLQTGDRVLLL 94
Query: 517 FPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKL 576
+P GL+ F GCLY G V PP + T+P V I+ + A L+L+NQ +I+
Sbjct: 95 YPFGLEYPAVFLGCLYAGLTAVPAFPPDKKRAVKTMPRVSAIIRDADARLILTNQELIET 154
Query: 577 LRSKEASNVLDSKAWPMTLDTDDMPKKKLPIMYRAP--TAEMLAYLDFSVSTTGMLAGIK 634
+ A D +A + + + P A LA+L ++ +TG G+
Sbjct: 155 VEFARA-EAEDPEALLIDASGGLGRAEADADAWTRPDALAGELAFLQYTSGSTGTPRGVM 213
Query: 635 MSHAAVTSLCRSMKIACELY--PSRHIALCLDP-YCGLGFALWCLSSIYSGHHSILIPPS 691
+ H +L + A E + P + + P Y +G L +Y G + L+ P+
Sbjct: 214 IGH---DNLLAHQRFAHEKFAQPEGSVTVSWLPFYHDMGLIGSLLYPLYCGGTTALMSPT 270
Query: 692 EVEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVVAE 751
P WL A+S+ + R + ELC + V + +G++L+ + AE
Sbjct: 271 AFLRRPMAWLDAISKLRARVSTGPNFAYELCVQ----RVEEADIEGLDLSHWELTISGAE 326
Query: 752 ERPRINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPSTVYVDLRALRND 811
R F + F+ G +P+ FG + P D L
Sbjct: 327 PL-RPATIQRFCERFAPAGFNPQTFMPCFGMAETTLMVSGAPKHALPRYERFDKAQLLGG 385
Query: 812 RVSLVERGS--PHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNASGYF 869
+ L G+ S + G + +V +PET + + GEIWV+ P GY
Sbjct: 386 QAVLAADGALEADSRVYVSCGTPMSEHEVAIVDPETHARRPEGRQGEIWVRGPSVGRGY- 444
Query: 870 TIYGDESDYADHFSAQL 886
+GD F+ ++
Sbjct: 445 --WGDPETSTRRFAGRI 459
Score = 48.4 bits (110), Expect = 0.001
Identities = 80/392 (20%), Positives = 133/392 (33%), Gaps = 10/392 (2%)
Query: 1 MLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLASVL-NGMHVIFIPYALMKVSPA 59
+LAH R EG V L F + GL ++L + G + P A ++ P
Sbjct: 219 LLAHQRFAHEKFAQPEGSVTVSWLPFYHDMGLIGSLLYPLYCGGTTALMSPTAFLR-RPM 277
Query: 60 SWMHMITKHRASIAIVKSRDLHWGLLATRDHKEISLSSLRMLLVADGANPWSLSSCDQFL 119
+W+ I+K RA ++ + + + L L GA P ++ +F
Sbjct: 278 AWLDAISKLRARVSTGPNFAYELCVQRVEEADIEGLDLSHWELTISGAEPLRPATIQRFC 337
Query: 120 SVFQSKGVRGDAICPCACSSESMTVCIXXXXXXXXXXXXXVLSMSGLSYGVVRVDAENSL 179
F G PC +E+ + + V+ D
Sbjct: 338 ERFAPAGFNPQTFMPCFGMAETTLMVSGAPKHALPRYERFDKAQLLGGQAVLAADGALEA 397
Query: 180 TSLTLQDCGQVMPSCVIVVVKMEGPAYLCKTDEVGEICVLSGATGSGYWGLPGLTNTVFR 239
S CG M + +V E A + + GEI V + G GYWG P + F
Sbjct: 398 DSRVYVSCGTPMSEHEVAIVDPETHARRPEGRQ-GEIWVRGPSVGRGYWGDPETSTRRFA 456
Query: 240 VRPLDSDGEPIGEEHYVRSXXXXXXXXXXXXXXXXSRDGLMTVTGRKHNMDDIIATVLAV 299
R EP + R+ D L+ G+ H D+ V
Sbjct: 457 GRIRGE--EPSPSWPWFRTDDTGFVHDGELYGTGRLAD-LLVSGGQVHQPHDLERDV--S 511
Query: 300 EPMKFIYRGRIAVFSVRVLRDE-RICIVAEQRPDCGEEESFQWMSRVLQAVDSIHQVGIY 358
E + + +A F R R E +C+ A R + + + + + H + +
Sbjct: 512 EGDAPLAKDAVA-FMARGERGEPLVCLAATGRRSMAARDREAVCEAIFERILAEHGLALD 570
Query: 359 CLALVQPNFLPKTPLGGIHLSECKRRFLEGTL 390
+ L+ P + KT G + ++ EG L
Sbjct: 571 RVLLIPPRTVAKTTSGKLRRYRYRQAMSEGEL 602
>UniRef50_Q11ZV6 Cluster: AMP-dependent synthetase and ligase; n=1;
Polaromonas sp. JS666|Rep: AMP-dependent synthetase and
ligase - Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 608
Score = 101 bits (241), Expect = 1e-19
Identities = 99/452 (21%), Positives = 186/452 (41%), Gaps = 19/452 (4%)
Query: 453 QFISQILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDH 512
Q I + L + A+ T + + + L G V ++ L +A I LL + GD
Sbjct: 33 QSILRNLDFHAEVTPEKLAYRFLPDAGGVPIEISYGSLRTRAWAIAAGLLSLAK--PGDR 90
Query: 513 VALIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQS 572
++ P GL+ I AF GCLY G + V + PP P L ++ + L ++ +
Sbjct: 91 ALIMLPSGLEFIQAFLGCLYAGVIAVPLYPPRPNQNFQRLASIHA---SATPALAITTAA 147
Query: 573 VIKLLRSKEASNVLDSKAWPMTLDTDDMPKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAG 632
+ L+++ +++ + + ++ P P++ +A++ ++ +T G
Sbjct: 148 QLPGLKTRFQADIHHEQMNWVAIEALMQEASVTP--RPLPSSTDIAFIQYTSGSTSAPKG 205
Query: 633 IKMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIPPSE 692
+ +SH + ++ A + H+ L + +G L +Y G L+
Sbjct: 206 VVLSHGTIVHNQEQIRKAFRHDETDHVMGWLPAFHDMGLIGNILQPLYLGIGCTLMSHLS 265
Query: 693 VEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVVAEE 752
P WL A+S Y+ + +LC + +++ + G+NL+ + AE
Sbjct: 266 FLQRPFRWLQAISMYQATTSGGPNFAYQLCVQ----KISEEQKAGLNLSSWKLAFCGAEV 321
Query: 753 RPRINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPSTV-YVDLRALRND 811
R N FS+ F G +A+ +G + + GA++ + + + ALR
Sbjct: 322 -VRPETINQFSQAFHRCGFDRQAIYPCYGL-AEATLFVAGAAAKDDALIRSYSAEALRGG 379
Query: 812 RVSLVERGSPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNASGYFTI 871
R V R + C M S V NP T + +GEIW+ S A GY
Sbjct: 380 RA--VFRVPDETTCSMVSCGTTFDHDVRIVNPATSIEQQAGEVGEIWIHSGSVALGY--- 434
Query: 872 YGDESDYADHFSAQLVTGNTGEVYARTGYLGF 903
+ ++ + F ++ + + + RTG LGF
Sbjct: 435 WNNDVLTREVFDGRITSDTLEKSFLRTGDLGF 466
Score = 66.9 bits (156), Expect = 3e-09
Identities = 86/381 (22%), Positives = 144/381 (37%), Gaps = 13/381 (3%)
Query: 11 ACNYTEGEHMVCVLDFKRETGLWHAVLASVLNGMHVIFIPYALMKVSPASWMHMITKHRA 70
A + E +H++ L + GL +L + G+ + + P W+ I+ ++A
Sbjct: 223 AFRHDETDHVMGWLPAFHDMGLIGNILQPLYLGIGCTLMSHLSFLQRPFRWLQAISMYQA 282
Query: 71 SIAIVKSRDLHWGLLATRDHKEISLSSLRMLLVADGANPWSLSSCDQFLSVFQSKGVRGD 130
+ + + + + ++ L+ L GA + +QF F G
Sbjct: 283 TTSGGPNFAYQLCVQKISEEQKAGLNLSSWKLAFCGAEVVRPETINQFSQAFHRCGFDRQ 342
Query: 131 AICPCACSSES-MTVCIXXXXXXXXXXXXXVLSMSGLSYGVVRVDAENSLTSLTLQDCGQ 189
AI PC +E+ + V ++ G V RV E T+ ++ CG
Sbjct: 343 AIYPCYGLAEATLFVAGAAAKDDALIRSYSAEALRG-GRAVFRVPDE---TTCSMVSCGT 398
Query: 190 VMPSCVIVVVKMEGPAYLCKTDEVGEICVLSGATGSGYWGLPGLTNTVFRVRPLDSDGEP 249
V +V + + EVGEI + SG+ GYW LT VF R + SD
Sbjct: 399 TFDHDVRIV--NPATSIEQQAGEVGEIWIHSGSVALGYWNNDVLTREVFDGR-ITSDTL- 454
Query: 250 IGEEHYVRSXXXXXXXXXXXXXXXXSRDGLMTVTGRKHNMDDIIATVLAVEPMKFIYRGR 309
E+ ++R+ L+ V GR H DI TV P F G
Sbjct: 455 --EKSFLRTGDLGFFDEGKNLFITGRLKDLIIVRGRNHAPTDIEFTVERSHP-SFRQAG- 510
Query: 310 IAVFSVRVLRDERICIVAEQRPDCGEEESFQWMSRVLQAVDSIHQVGIYCLALVQPNFLP 369
A F+V + +ER+ + E + + + V H + +Y + V+ LP
Sbjct: 511 CAAFAVDIDGEERLVVAQEIERTARDVDPLGARDAACEQVTREHGLKVYEIVFVRHAALP 570
Query: 370 KTPLGGIHLSECKRRFLEGTL 390
+T G I C + +L G L
Sbjct: 571 RTSSGKIQRYLCAQHYLNGML 591
>UniRef50_Q4BZ64 Cluster: AMP-dependent synthetase and ligase; n=1;
Crocosphaera watsonii WH 8501|Rep: AMP-dependent
synthetase and ligase - Crocosphaera watsonii
Length = 579
Score = 100 bits (240), Expect = 2e-19
Identities = 86/403 (21%), Positives = 166/403 (41%), Gaps = 15/403 (3%)
Query: 507 VNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATL 566
+N V L++P GL+ + AF GCL + V P +P + + ++ I+ + +
Sbjct: 1 MNKKSRVLLLYPQGLEFLTAFLGCLNADMIAV---PAYPPKGNQKMSRLQAIIKNCQPDV 57
Query: 567 VLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKKLPIMYRAPTAEMLAYLDFSVST 626
+L+ S+++ ++SK ++DS + TD + + +A+L ++ +
Sbjct: 58 ILTTSSLLEKVKSK-LGQIIDSNQIKC-ICTDQLGTISEELADNLTIDNEIAFLQYTSGS 115
Query: 627 TGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSI 686
TG G+ +SH + ++ A +L L + +G + +Y+G +
Sbjct: 116 TGNPKGVIVSHENILHNSAYIQTAFQLTEGSVSVTWLPSFHDMGLIDGIIQPLYTGFLGV 175
Query: 687 LIPPSEVEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTC 746
++ P P WL A+S Y+ + +LC + V +++ ++L+C +
Sbjct: 176 IMSPQAFLQKPIRWLEAISYYRATHSGGPNLGYDLCVE----KVTNEQTRNLDLSCWLSA 231
Query: 747 VVVAEERPRINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPSTVYVDLR 806
+E L +K F + G +G + + G EP + +D
Sbjct: 232 YNGSEPIQYKTLERFINK-FQSCGFKSHYFYPCYGMAESTLMVSGGELEKEPICLNLDAE 290
Query: 807 ALRNDRVSLVERGSPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNAS 866
L + + S L+ G + NPET+ C D+ +GE+WV A
Sbjct: 291 QLAKNIICEGNGNSTKVKELVGCGHSWLDTDIQIVNPETETICEDNQIGEVWVSGSSIAQ 350
Query: 867 GYFTIYGDESDYADHFSAQLVTGNTGEVYARTGYLGFLRRTEI 909
GY+ +S+ + + G Y RTG LGF+R E+
Sbjct: 351 GYW----QQSEVNTAVFSNKIDSLNG-CYLRTGDLGFIRNQEL 388
Score = 81.4 bits (192), Expect = 1e-13
Identities = 86/392 (21%), Positives = 161/392 (41%), Gaps = 15/392 (3%)
Query: 1 MLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLASVLNG-MHVIFIPYALMKVSPA 59
+L + + A TEG V L + GL ++ + G + VI P A ++ P
Sbjct: 129 ILHNSAYIQTAFQLTEGSVSVTWLPSFHDMGLIDGIIQPLYTGFLGVIMSPQAFLQ-KPI 187
Query: 60 SWMHMITKHRASIAIVKSRDLHWGLLATRDHKEISLSSLRMLLVADGANPWSLSSCDQFL 119
W+ I+ +RA+ + + + + + +L L +G+ P + ++F+
Sbjct: 188 RWLEAISYYRATHSGGPNLGYDLCVEKVTNEQTRNLDLSCWLSAYNGSEPIQYKTLERFI 247
Query: 120 SVFQSKGVRGDAICPCACSSESMTVCIXXXXXXXXXXXXXVLSMSGLSYGVVRVDAENSL 179
+ FQS G + PC +ES T+ + L L+ ++ NS
Sbjct: 248 NKFQSCGFKSHYFYPCYGMAES-TLMVSGGELEKEPICLN-LDAEQLAKNIICEGNGNST 305
Query: 180 TSLTLQDCGQVMPSCVIVVVKMEGPAYLCKTDEVGEICVLSGATGSGYWGLPGLTNTVFR 239
L CG I +V E +C+ +++GE+ V + GYW + VF
Sbjct: 306 KVKELVGCGHSWLDTDIQIVNPETET-ICEDNQIGEVWVSGSSIAQGYWQQSEVNTAVFS 364
Query: 240 VRPLDSDGEPIGEEHYVRSXXXXXXXXXXXXXXXXSRDGLMTVTGRKHNMDDIIATVLAV 299
+ +G Y+R+ +D L+ + G+ + DI TV
Sbjct: 365 NKIDSLNG------CYLRTGDLGFIRNQELFITGRIKD-LIIIWGKNYYPQDIENTVQNC 417
Query: 300 EPMKFIYRGRIAVFSVRVLRDERICIVAE-QRPDCGEEESFQWMSRVLQAVDSIHQVGIY 358
P + + A FS+ V ER+ IV E +R ++ + + + +AV +++ +Y
Sbjct: 418 HPA--LRKDGAAAFSLEVDNQERLVIVQEVERTYLRNLDTNEVVKAIREAVSLEYELQVY 475
Query: 359 CLALVQPNFLPKTPLGGIHLSECKRRFLEGTL 390
+AL++P + KT G I C+ +++ TL
Sbjct: 476 AIALIKPASIAKTSSGKIQRYACRDQYITQTL 507
Score = 37.1 bits (82), Expect = 2.6
Identities = 13/31 (41%), Positives = 21/31 (67%)
Query: 952 VFVVGALDETIMLRGMRYHPIDIENSVMRCH 982
+F+ G + + I++ G Y+P DIEN+V CH
Sbjct: 388 LFITGRIKDLIIIWGKNYYPQDIENTVQNCH 418
>UniRef50_A6E0C1 Cluster: Non-ribosomal peptide synthase; n=1;
Roseovarius sp. TM1035|Rep: Non-ribosomal peptide
synthase - Roseovarius sp. TM1035
Length = 684
Score = 100 bits (239), Expect = 2e-19
Identities = 100/428 (23%), Positives = 177/428 (41%), Gaps = 25/428 (5%)
Query: 484 VLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPP 543
VL+ +L K+A + +L G + G VALIF G + A +G + G V + P
Sbjct: 53 VLSFEDLVKRASHVAGVLTAAG-CSHGARVALIFEHGPGFVIALFGAFFAGCAAVPVAVP 111
Query: 544 HPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWP--MTLDTDDMP 601
+ T + D + ++L++ ++ K L A + + A P + LDT D
Sbjct: 112 TNETKRTRAGAILAEADCA---VLLTSPAIAKTL----AEDGIGIAALPPIIALDTVDRA 164
Query: 602 KKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIAL 661
+P E +A + ++ +TG G+ ++ A+ + ++ + +
Sbjct: 165 ASFIPSRI---VPEDVAIIQYTSGSTGHPRGVVVTQGALHAQMCAIDLCLRSESEERVVT 221
Query: 662 CLDPYCGLGFALWCLSSIYSGHHSILIPPSEVEVNPALWLSAVSQYKVRDTFCSYGVMEL 721
L P +G L +++ G + ++ P P LWL +S+++ + +L
Sbjct: 222 WLPPEHDMGLMGGLLFNLWRGDPTYVLAPESFIRRPYLWLDTISKWRGTVSVAPNFAFDL 281
Query: 722 CTKGLGSSVNQLKSKGINLACVRTCVVVAEERPRINLTNSFSKLFSALGLSPRAVSTSFG 781
C +G+ ++LKS ++L+ R + AE L F+ +F +G P+ +G
Sbjct: 282 CVRGI--PADRLKS--LDLSSWRVALNGAEPVQPETLAR-FADVFKPVGFDPQCFLPCYG 336
Query: 782 CRVNIAICLQGASSPEPSTVYVDLRALRNDRVSLVERGSPHSLCLMESGKLLPGVKVITA 841
+ A +T + D AL RV + G+ CL+ SG + V
Sbjct: 337 LAEATLLVSGAARGGGATTHWFDPEALEAGRVVPLLAGT--GRCLVSSGPVRTTGGVRIV 394
Query: 842 NPETKGQCGDSHLGEIWVQSPHNASGYFTIYGDESDYADHFSAQLVTGNTGEVYARTGYL 901
PET C +GEIW+ SGY + + F TG+ Y R+G L
Sbjct: 395 EPETGVPCRSDRIGEIWIAGESVGSGY---HDRPEESVSTFGQFTATGD--GPYLRSGDL 449
Query: 902 GFLRRTEI 909
GFL E+
Sbjct: 450 GFLWNDEL 457
Score = 46.0 bits (104), Expect = 0.006
Identities = 59/250 (23%), Positives = 101/250 (40%), Gaps = 15/250 (6%)
Query: 4 HCRMLSV-ACNYTEGEHMVCV-LDFKRETGLWHAVLASVLNGMHV-IFIPYALMKVSPAS 60
H +M ++ C +E E V L + + GL +L ++ G + P + ++ P
Sbjct: 201 HAQMCAIDLCLRSESEERVVTWLPPEHDMGLMGGLLFNLWRGDPTYVLAPESFIR-RPYL 259
Query: 61 WMHMITKHRASIAIVKSRDLHW---GLLATRDHKEISLSSLRMLLVADGANPWSLSSCDQ 117
W+ I+K R ++++ + G+ A R K + LSS R+ L +GA P + +
Sbjct: 260 WLDTISKWRGTVSVAPNFAFDLCVRGIPADR-LKSLDLSSWRVAL--NGAEPVQPETLAR 316
Query: 118 FLSVFQSKGVRGDAICPCACSSESMTVCIXXXXXXXXXXXXXVLSMSGLSYGVVRVDAEN 177
F VF+ G PC +E+ + L G RV
Sbjct: 317 FADVFKPVGFDPQCFLPCYGLAEA--TLLVSGAARGGGATTHWFDPEALEAG--RVVPLL 372
Query: 178 SLTSLTLQDCGQVMPSCVIVVVKMEGPAYLCKTDEVGEICVLSGATGSGYWGLPGLTNTV 237
+ T L G V + + +V+ E C++D +GEI + + GSGY P + +
Sbjct: 373 AGTGRCLVSSGPVRTTGGVRIVEPE-TGVPCRSDRIGEIWIAGESVGSGYHDRPEESVST 431
Query: 238 FRVRPLDSDG 247
F DG
Sbjct: 432 FGQFTATGDG 441
>UniRef50_A1YBQ9 Cluster: AmbG; n=1; Sorangium cellulosum|Rep: AmbG
- Polyangium cellulosum (Sorangium cellulosum)
Length = 739
Score = 100 bits (239), Expect = 2e-19
Identities = 100/396 (25%), Positives = 170/396 (42%), Gaps = 26/396 (6%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNT-GDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPP 543
LT EL + A NL LE V GD V + + G + + LY G + V + P
Sbjct: 53 LTYRELERAAT---NLSLELASVAAPGDRVLVAYDSGPMYLVGVWAALYAGMIAVPVDPL 109
Query: 544 HPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKA-WPMTLDTDDMPK 602
P L + + S AT+ ++++S++ ++S + L + W + D + +
Sbjct: 110 GPDRPAANLTRLLNVTADSGATVCIASRSMLDAVKSHPGARQLTEQLRWVVPSLPDLLGR 169
Query: 603 KKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACEL---YPSRHI 659
T + +A L ++ +TG G ++HA++ L R++ I+ + +
Sbjct: 170 APGSPPAALRTEKDVAMLQYASGSTGAPKGTIVTHASLLMLARALLISTSAESPFGRPDV 229
Query: 660 ALCLDPY----CGLGFALWCLSSIYSGHHSILIPPSEVEVNPALWLSAVSQYKVRDTF-- 713
+ P G G + CL+ + I PS +PA+WL +S++K + +
Sbjct: 230 EVTWLPLTHSTAGYGLIMKCLTGATMS--AWYIAPSAFARSPAIWLRTISRHKGKQVYSV 287
Query: 714 CSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVVAEERPRINLTNSFSKLFSALGLSP 773
++ C SS + + K ++L+C T V+ E+ R +FS F G P
Sbjct: 288 APNFALDWCV----SSTTEAERKQLDLSCW-THVMSMGEKVRPETWKAFSDAFRESGFHP 342
Query: 774 RAVSTSFGCRVNIAICLQGASSPEPSTVYVDLRALRNDRVSLVERGSPHSLCLMESGKLL 833
+ +G + S TV D A+ D SLVE L L SG L
Sbjct: 343 KLFIAGYGMSETGYV---SGSVNGGKTVRFDRAAM--DEGSLVEAPEGGILLLSSSGFTL 397
Query: 834 PGVKVITANPETKGQCGDSHLGEIWVQSPHNASGYF 869
PGV+V +PET+ + +GEIWV +P +GY+
Sbjct: 398 PGVRVAIVDPETREVLPEGKIGEIWVSTPTAMTGYW 433
Score = 44.8 bits (101), Expect = 0.013
Identities = 48/210 (22%), Positives = 83/210 (39%), Gaps = 12/210 (5%)
Query: 182 LTLQDCGQVMPSCVIVVVKMEGPAYLCKTDEVGEICVLSGATGSGYWGLPGLTNTVFRVR 241
L L G +P + +V E L + ++GEI V + +GYW P T FR R
Sbjct: 388 LLLSSSGFTLPGVRVAIVDPETREVLPE-GKIGEIWVSTPTAMTGYWNRPEETEQQFRAR 446
Query: 242 PLDSDGEPIGEEHYVRSXXXXXXXXXXXXXXXXSRDGLMTVTGRKHNMDDIIATVLAVEP 301
D G + RS R ++ + GRKH +DI +T+
Sbjct: 447 AADGSGP------FFRS-GDMGAFYGGNLFVTGRRKSIVVIRGRKHYAEDIESTL--ERA 497
Query: 302 MKFIYRGRIAVFSVRVLRDERICIVAEQRPDCGEEESFQWMSRVLQAVDSIH-QVGIYCL 360
+ ++ F+ V E + I + R + F+ + +++V + V ++ +
Sbjct: 498 LDWLGANSSIAFADDVNGVEELFIAVDPR-GARDGVGFEERTDAIRSVVAREFGVRVHEV 556
Query: 361 ALVQPNFLPKTPLGGIHLSECKRRFLEGTL 390
+ LP+T +G + CK F G L
Sbjct: 557 LFLAAGQLPRTSMGKVSRVSCKDLFRSGEL 586
>UniRef50_A5NTM2 Cluster: AMP-dependent synthetase and ligase; n=1;
Methylobacterium sp. 4-46|Rep: AMP-dependent synthetase
and ligase - Methylobacterium sp. 4-46
Length = 958
Score = 99 bits (238), Expect = 3e-19
Identities = 98/391 (25%), Positives = 164/391 (41%), Gaps = 19/391 (4%)
Query: 484 VLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPP 543
VLT A+L ++A R+ LL G + GD VA++ P G D AF+GCL G VPV + PP
Sbjct: 163 VLTYADLDRRARRVAAGLLGHG-LAPGDRVAIMLPTGPDFFPAFFGCLLAGGVPVPLYPP 221
Query: 544 HPQ-NLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPK 602
+ + L I+ + +++++ +V R V + D D
Sbjct: 222 FRRAQVQDHLERQAGILTNAAPGILITDSAVAPFARLLP-DRVEGLRVLTTAADLADAEP 280
Query: 603 KKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIALC 662
P+ T LA + ++ +TG G+ ++HA + + R+M A + +
Sbjct: 281 LAEPV---PATGASLALIQYTSGSTGDPKGVTLTHANLLANVRAMGEALGASSADVVVSW 337
Query: 663 LDPYCGLGFALWCLSSIYSGHHSILIPPSEVEVNPALWLSAVSQYKVRDTFCSYGVMELC 722
L Y +G L S+Y G ++++PP +P WL A+ +++ + ELC
Sbjct: 338 LPLYHDMGLIGCWLGSLYFGAPAVILPPLAFLADPGSWLWAIHRHRGTISAAPNFAYELC 397
Query: 723 TKGLGSSVNQLKSKGINLACVRTCVVVAEERPRINLTNSFSKLFSALGLSPRAVSTSFG- 781
K S+ G++L +R AE L F++ F A GL A++ +G
Sbjct: 398 LK----SLRDEDVAGLDLGSLRVLTNGAEPVSPDTLAR-FARRFGAFGLQTSALTPVYGL 452
Query: 782 --CRVNIAICLQGASSPEPSTVYVDLRAL-RNDRVSLVERGSPHSLCLMESGKLLPGVKV 838
C V +A G P ++D AL R G S G+ L G ++
Sbjct: 453 AECAVGLAFPPLGRG---PRIDWIDRAALSREGTARPAPPGEAGSTAFAACGRPLRGHQI 509
Query: 839 ITANPETKGQCGDSHLGEIWVQSPHNASGYF 869
+ E + + G + + P +GYF
Sbjct: 510 RIVD-EAGRELPERREGRLQFRGPSATAGYF 539
Score = 48.0 bits (109), Expect = 0.001
Identities = 32/134 (23%), Positives = 58/134 (43%)
Query: 1 MLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLASVLNGMHVIFIPYALMKVSPAS 60
+LA+ R + A + + +V L + GL L S+ G + +P P S
Sbjct: 315 LLANVRAMGEALGASSADVVVSWLPLYHDMGLIGCWLGSLYFGAPAVILPPLAFLADPGS 374
Query: 61 WMHMITKHRASIAIVKSRDLHWGLLATRDHKEISLSSLRMLLVADGANPWSLSSCDQFLS 120
W+ I +HR +I+ + L + RD L + ++ +GA P S + +F
Sbjct: 375 WLWAIHRHRGTISAAPNFAYELCLKSLRDEDVAGLDLGSLRVLTNGAEPVSPDTLARFAR 434
Query: 121 VFQSKGVRGDAICP 134
F + G++ A+ P
Sbjct: 435 RFGAFGLQTSALTP 448
>UniRef50_Q8YTN6 Cluster: Alr2678 protein; n=2; Nostocaceae|Rep:
Alr2678 protein - Anabaena sp. (strain PCC 7120)
Length = 1206
Score = 98.7 bits (235), Expect = 7e-19
Identities = 118/454 (25%), Positives = 182/454 (40%), Gaps = 43/454 (9%)
Query: 458 ILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIF 517
+LR Q D V F V LT EL KA I + L+ R G+ V L++
Sbjct: 22 VLRAWTQQKGDAVGFAFWQDDKQVH--LTYTELDHKARAIA-VHLQAMRWQ-GERVLLMY 77
Query: 518 PPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLL 577
PPGL+LI A GC Y G V V + PP P N T L + I + ++A +L+ S+ L
Sbjct: 78 PPGLELIAALMGCFYAGLVAVPVYPPRPNNNITRLLS---IGEDAQAKGILTKVSLENSL 134
Query: 578 RSKEASNVLDSKAWPMTLDTDDMPKKKLPIMYRAP--TAEMLAYLDFSVSTTGMLAGIKM 635
K+ S +A P + TD + + ++ P TA+ LA L ++ +TG G+ +
Sbjct: 135 --KQVSKNTAFEALP-KVATDSI-ILSVGEAWQNPQLTADSLALLQYTSGSTGTPKGVML 190
Query: 636 SHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIPPSEVEV 695
SH + + + H+ L PY +G L +Y G L+ P
Sbjct: 191 SHGNLLHNLGQIYQRFGHSANTHVVSWLPPYHDMGLIGGILQPLYGGFPVTLMSPVAFLQ 250
Query: 696 NPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVVAEERPR 755
P WL A+SQ + + E+C + ++ + ++L+ AE R
Sbjct: 251 KPLRWLQAISQTQATTSGAPNFAYEMCVR----NIRLDECLDLDLSSWELAFTGAEP-IR 305
Query: 756 INLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPSTVYVDLRALRNDRVSL 815
F+ F G A +G + + G + E + SL
Sbjct: 306 QETLERFATTFKTYGFRREAFYPCYGL-AEATLFVTGKNKDE--------IVFNHTSQSL 356
Query: 816 VERGSPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNASGYFTIYGDE 875
V GSP +I NPE++ C GEIW++ A GY + +
Sbjct: 357 VSCGSPSD-----------DQTIIIVNPESREPCAAGEEGEIWLKGASVAQGY---WQNP 402
Query: 876 SDYADHFSAQLVTGNTGEVYARTGYLGFLRRTEI 909
+ F L +G G + RTG LG+L E+
Sbjct: 403 QETKATFQGALASGTGG--FLRTGDLGYLNSGEL 434
Score = 66.1 bits (154), Expect = 5e-09
Identities = 82/378 (21%), Positives = 144/378 (38%), Gaps = 33/378 (8%)
Query: 14 YTEGEHMVCVLDFKRETGLWHAVLASVLNGMHVIFIPYALMKVSPASWMHMITKHRASIA 73
++ H+V L + GL +L + G V + P W+ I++ +A+ +
Sbjct: 208 HSANTHVVSWLPPYHDMGLIGGILQPLYGGFPVTLMSPVAFLQKPLRWLQAISQTQATTS 267
Query: 74 IVKSRDLHWGLLATRDHKEISLSSLRMLLVADGANPWSLSSCDQFLSVFQSKGVRGDAIC 133
+ + R + + L L GA P + ++F + F++ G R +A
Sbjct: 268 GAPNFAYEMCVRNIRLDECLDLDLSSWELAFTGAEPIRQETLERFATTFKTYGFRREAFY 327
Query: 134 PCACSSESMTVCIXXXXXXXXXXXXXVLSMSGLSYGVVRVDAENSLTSLTLQDCGQVMPS 193
PC +E+ L ++G + + + TS +L CG
Sbjct: 328 PCYGLAEA------------------TLFVTGKNKDEIVFNH----TSQSLVSCGSPSDD 365
Query: 194 CVIVVVKMEGPAYLCKTDEVGEICVLSGATGSGYWGLPGLTNTVFRVRPLDSDGEPIGEE 253
I++V E C E GEI + + GYW P T F+ G
Sbjct: 366 QTIIIVNPESREP-CAAGEEGEIWLKGASVAQGYWQNPQETKATFQGALASGTGG----- 419
Query: 254 HYVRSXXXXXXXXXXXXXXXXSRDGLMTVTGRKHNMDDIIATVLAVEPMKFIYRGRIAVF 313
++R+ +D +M + G+ + DI A V P Y G A F
Sbjct: 420 -FLRTGDLGYLNSGELFVTGRIKD-VMIIRGQNYYPHDIEAAVSQCHPALSAYWG--AAF 475
Query: 314 SVRVLRDERICIVAE-QRPDCGEEESFQWMSRVLQAVDSIHQVGIYCLALVQPNFLPKTP 372
SV V +ER+ +V E +R + ++ + AV + +Y + L++P +PKT
Sbjct: 476 SVEVDGEERLVVVQEVERSSWRRLDEDGIIAAIRGAVSCEFGLQVYGICLLKPGSIPKTS 535
Query: 373 LGGIHLSECKRRFLEGTL 390
G + C+ F+ G L
Sbjct: 536 SGKVQRFACREGFVCGGL 553
Score = 37.5 bits (83), Expect = 1.9
Identities = 13/35 (37%), Positives = 24/35 (68%)
Query: 952 VFVVGALDETIMLRGMRYHPIDIENSVMRCHKKIA 986
+FV G + + +++RG Y+P DIE +V +CH ++
Sbjct: 434 LFVTGRIKDVMIIRGQNYYPHDIEAAVSQCHPALS 468
>UniRef50_Q3JM63 Cluster: Peptide synthetase NRPS5-4-3; n=16;
Burkholderia|Rep: Peptide synthetase NRPS5-4-3 -
Burkholderia pseudomallei (strain 1710b)
Length = 1005
Score = 97.9 bits (233), Expect = 1e-18
Identities = 102/450 (22%), Positives = 180/450 (40%), Gaps = 15/450 (3%)
Query: 458 ILRWRAQSTSDHVIFTLL-NAKGAVSKVLTCAELHKKAERIGNLLLEK--GRVNTGDHVA 514
I+R RA D +T L +GA +++L A L ++A I L + G +
Sbjct: 417 IVRARADRQPDRPAYTYLPEQEGAPAELLDYASLVQRAHAIAAALDRRLAGAPDAPRMAM 476
Query: 515 LIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVI 574
L+F PG D + AF+GCL + + + P P TL IV + LVL+++
Sbjct: 477 LLFAPGPDFLAAFWGCLSARVIAIPAQLPRPGRCAATLEA---IVRNAGVRLVLASRPQA 533
Query: 575 KLLRSKEASNVLDSKAWPMTLDTDDMPKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIK 634
+ A + + + +D P R P A+ +A+L ++ +T G+
Sbjct: 534 DAIGRTLARSPALAGLDTLFVDDALADGAGRPAPAR-PAADDIAFLQYTSGSTSRPKGVV 592
Query: 635 MSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIPPSEVE 694
+ H + + R + A L + + + Y +G L +YSG H + + P+
Sbjct: 593 VRHRNLVANERMIAQAMSLDHASTSVVWMPHYHDMGLIGGMLQPLYSGAHCVAMAPTTFL 652
Query: 695 VNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVVAEERP 754
P WL A++Q++ + LC + + ++ G++L+ R AE
Sbjct: 653 KRPLRWLRAIAQWRAVSSGGPDFAYRLCVERIAPE----QAAGLDLSSWRVAFNGAEP-V 707
Query: 755 RINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPSTVYVDLRALRNDRVS 814
R +F++ F G A +G + G + ++ AL R
Sbjct: 708 RAATIAAFAERFGPAGFRAHASYPCYGMAEATLLAAGGRAGDGAHVRWISAAALAAGRAE 767
Query: 815 LVERGSPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNASGYFTIYGD 874
G + + G G ++ +P T+ + D +GE+W+ PH A GY
Sbjct: 768 PPAPGDAGTAAVC-CGAPPAGARLAVVDPATRQRRADGLVGELWIAGPHVADGYHR--AP 824
Query: 875 ESDYADHFSAQLVTGNTGEVYARTGYLGFL 904
E+ A +A + RTG LGF+
Sbjct: 825 EASAAAFGAAIAGPEPDAGPWLRTGDLGFV 854
>UniRef50_Q7CT18 Cluster: AGR_L_2326p; n=2; Agrobacterium
tumefaciens str. C58|Rep: AGR_L_2326p - Agrobacterium
tumefaciens (strain C58 / ATCC 33970)
Length = 770
Score = 94.3 bits (224), Expect = 2e-17
Identities = 99/426 (23%), Positives = 178/426 (41%), Gaps = 25/426 (5%)
Query: 486 TCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTI-RPPH 544
T EL+ + + + N + + G V G V +++PPGL I AF GCL+ GAVPV + P
Sbjct: 76 TWGELNARVKIVSNEVSKTGLVGQGGRVLIVYPPGLAFIAAFLGCLHAGAVPVPVPAPRR 135
Query: 545 PQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKK 604
+ +H L + D + +V + + + +LL + + P D ++P +
Sbjct: 136 NEGIHRWLHIAK---DAGISGIVCA-EELKELLEPLQRAVGHGFCLAPSGAD-PNIPLRD 190
Query: 605 LPIMYRAPT---AEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIAL 661
L AP +A+L ++ +T G+ ++HA + + R + +A P A
Sbjct: 191 LAPSSSAPAVLDGNRIAFLQYTSGSTSDPKGVMVTHANLMANLRQISLAFHYGPEDRSAT 250
Query: 662 CLDPYCGLGFALWCLSSIYSGHHSILIPPSEVEVNPALWLSAVSQYKVRDTFCSYGVMEL 721
L Y +G LS I++G ++ P+ P +L +Q + E
Sbjct: 251 WLPHYHDMGLIDGILSPIFNGFPVSIMAPASFLRRPLRFLELATQNRATIIGGPNFAYEH 310
Query: 722 CTKGLGSSVNQLKSKGINLACVRTCVVVAEERPRINLTNSFSKLFSALGLSPRAVSTSFG 781
C + + ++L+ VR AE R + FS LF+ G A +G
Sbjct: 311 CADRYSAE----GAAQLDLSAVRIAYNGAEP-VRPHTLRRFSALFADHGFRHDAFYCCYG 365
Query: 782 CRVNIAICLQGASSPEPSTVYV---DLRALRNDRVSLVERGSPH-SLCLMESGKLLPGVK 837
+ + L G + +P + + A + + L H ++ L G+ ++
Sbjct: 366 -QAEATLFLTGNAPSDPPQLRCFERETLAKQGTALPLPAGADEHDAIELAACGRPGADIE 424
Query: 838 VITANPETKGQCGDSHLGEIWVQSPHNASGYFTIYGDESDYADHFSAQLVTGNTGEVYAR 897
++ PE D +GE+W++ P+ GY+ ++ D Q + G G + R
Sbjct: 425 IVVMEPEENRLLDDGQVGELWIRGPNITPGYWARAKASAESFD----QKIAGEGG--WRR 478
Query: 898 TGYLGF 903
TG LGF
Sbjct: 479 TGDLGF 484
Score = 74.5 bits (175), Expect = 1e-11
Identities = 86/398 (21%), Positives = 167/398 (41%), Gaps = 25/398 (6%)
Query: 1 MLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLASVLNGMHVIFIPYALMKVSPAS 60
++A+ R +S+A +Y + L + GL +L+ + NG V + A P
Sbjct: 229 LMANLRQISLAFHYGPEDRSATWLPHYHDMGLIDGILSPIFNGFPVSIMAPASFLRRPLR 288
Query: 61 WMHMITKHRASIAIVKSRDLHWGLLATRDHKE----ISLSSLRMLLVADGANPWSLSSCD 116
++ + T++RA+I + + + A R E + LS++R + +GA P +
Sbjct: 289 FLELATQNRATI--IGGPNFAYEHCADRYSAEGAAQLDLSAVR--IAYNGAEPVRPHTLR 344
Query: 117 QFLSVFQSKGVRGDAICPCACSSES---MTVCIXXXXXXXXXXXXXVLSMSGLSYGVVRV 173
+F ++F G R DA C +E+ +T L+ G + +
Sbjct: 345 RFSALFADHGFRHDAFYCCYGQAEATLFLTGNAPSDPPQLRCFERETLAKQGTALPLPAG 404
Query: 174 DAENSLTSLTLQDCGQVMPSCVIVVVKMEGPAYLCKTDEVGEICVLSGATGSGYWGLPGL 233
E+ ++ L CG+ IVV++ E L +VGE+ + GYW
Sbjct: 405 ADEHD--AIELAACGRPGADIEIVVMEPEENRLL-DDGQVGELWIRGPNITPGYWARAKA 461
Query: 234 TNTVFRVRPLDSDGEPIGEEHYVRSXXXXXXXXXXXXXXXXSRDGLMTVTGRKHNMDDII 293
+ F D + GE + R+ +D L+ + G+ H+ +DI
Sbjct: 462 SAESF-------DQKIAGEGGWRRTGDLGFRHEGQYFITGRLKD-LIIIRGQNHHPEDIE 513
Query: 294 ATVLAVEPMKFIYRGRIAVFSVRVLRDERICIVAE-QRPDCGEEESFQWMSRVLQAVDSI 352
T A + +GR F++ V +E++ +V E R ++ + + ++ +
Sbjct: 514 QT--AFSSHSALAQGRAGAFALDVDGEEQVGLVCELTRDGLRNLDAEAVLQAIRGSISRV 571
Query: 353 HQVGIYCLALVQPNFLPKTPLGGIHLSECKRRFLEGTL 390
H++ + + L++P+ LP+TP G + C++ L G L
Sbjct: 572 HKLKLATIVLIRPSSLPRTPSGKVRRFACRQDLLNGNL 609
Score = 35.9 bits (79), Expect = 5.9
Identities = 13/35 (37%), Positives = 21/35 (60%)
Query: 953 FVVGALDETIMLRGMRYHPIDIENSVMRCHKKIAE 987
F+ G L + I++RG +HP DIE + H +A+
Sbjct: 491 FITGRLKDLIIIRGQNHHPEDIEQTAFSSHSALAQ 525
>UniRef50_Q7D7S1 Cluster: Acyl-CoA synthase; n=15;
Mycobacterium|Rep: Acyl-CoA synthase - Mycobacterium
tuberculosis
Length = 620
Score = 93.9 bits (223), Expect = 2e-17
Identities = 78/366 (21%), Positives = 159/366 (43%), Gaps = 15/366 (4%)
Query: 510 GDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLS 569
GD VA++ P G+D +C FY + G V V + P L T + S+ ++L+
Sbjct: 92 GDRVAILAPQGIDYVCGFYAAIKAGTVAVPLFAPELPGHAERLDTA---LRDSEPAVILT 148
Query: 570 NQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKKLPIMYRAP-TAEMLAYLDFSVSTTG 628
+ + N + P L D +P ++ + + +++L ++ +T
Sbjct: 149 TAAAKNAVEG--FLNNVPRLRKPTVLVIDQIPDREGELFVPVELDIDAVSHLQYTSGSTR 206
Query: 629 MLAGIKMSHAAV-TSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSIL 687
G++++H AV T+L + + L + H L Y +G ++ ++Y GH +++
Sbjct: 207 PPVGVEITHRAVGTNLVQMILSIDLLNRNTHGVSWLPLYHDMGLSMIGFPAVYGGHSTLM 266
Query: 688 IPPSEVEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCV 747
P + V P W+ A+S+ R + ++ L ++G ++ +
Sbjct: 267 SPTAFVR-RPLRWIQALSEGS-RTGRVVTAAPNFAYE--WAAQRGLPAQGDDVDLSNVVL 322
Query: 748 VVAEERPRINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPSTVYVDLRA 807
++ E I+ +F+K F+ GL A S+G + + EP+ VY+D
Sbjct: 323 IIGSEPVSIDAVTTFNKAFAPYGLPRTAFKPSYGIAEATLLVATIDHAAEPTVVYLDPEQ 382
Query: 808 LRNDRVSLVERGSPHSLCLMESGKLLPGVKVITANPETKGQCG----DSHLGEIWVQSPH 863
L + V +P+++ + G + + + +P+T + G D +GE+W+Q +
Sbjct: 383 LGAGHATRVAPDAPNAVVHVSCGHVARSLWAVIVDPDTGPEAGAELPDGEIGEVWLQGDN 442
Query: 864 NASGYF 869
A GY+
Sbjct: 443 VARGYW 448
Score = 74.1 bits (174), Expect = 2e-11
Identities = 91/394 (23%), Positives = 157/394 (39%), Gaps = 35/394 (8%)
Query: 19 HMVCVLDFKRETGLWHAVLASVLNGMHVIFIPYALMKVSPASWMHMITKHRASIAIVKSR 78
H V L + GL +V G + P A ++ P W+ +++ + +V +
Sbjct: 237 HGVSWLPLYHDMGLSMIGFPAVYGGHSTLMSPTAFVR-RPLRWIQALSEGSRTGRVVTAA 295
Query: 79 D---LHW----GLLATRDHKEISLSSLRMLLVADGANPWSLSSCDQFLSVFQSKGVRGDA 131
W GL A D ++ LS++ +++ G+ P S+ + F F G+ A
Sbjct: 296 PNFAYEWAAQRGLPAQGD--DVDLSNVVLII---GSEPVSIDAVTTFNKAFAPYGLPRTA 350
Query: 132 ICPCACSSESMTVCIXXXXXXXXXXXXXVLSMSGLSYGV-VRVDAENSLTSLTLQDCGQV 190
P +E+ + G + V DA N++ ++ CG V
Sbjct: 351 FKPSYGIAEATLLVATIDHAAEPTVVYLDPEQLGAGHATRVAPDAPNAVVHVS---CGHV 407
Query: 191 MPSCVIVVVKME-GPAYLCKTD--EVGEICVLSGATGSGYWGLPGLTNTVFRVR---PL- 243
S V+V + GP + E+GE+ + GYWG P T F R PL
Sbjct: 408 ARSLWAVIVDPDTGPEAGAELPDGEIGEVWLQGDNVARGYWGRPEETRMTFGARLQSPLA 467
Query: 244 ---DSDGEPIGEEHYVRSXXXXXXXXXXXXXXXXSRDGLMTVTGRKHNMDDIIATVLAVE 300
+DG I ++ ++R+ D L+T+ GR H DI AT
Sbjct: 468 EGSHADGSAI-DDTWLRTGDLGVYLDGELYITGRIAD-LLTIDGRNHYPQDIEATAAEAS 525
Query: 301 PMKFIYRGRIAVFSVRVL----RDERICIVAEQRPDCGEEESFQWMSRVLQAVDSIHQVG 356
PM + RG I F+V R++R+ I+AE+ + + + AV + H +
Sbjct: 526 PM--VRRGYITAFTVPASDGDDRNQRLVIIAERAAGTSRSDPRPALDAIRAAVCNRHGLS 583
Query: 357 IYCLALVQPNFLPKTPLGGIHLSECKRRFLEGTL 390
+ L+ + +P+T G + C+ ++L G L
Sbjct: 584 VADLSFLPAGAIPRTTSGKLARQACRAQYLSGRL 617
>UniRef50_A7NZW0 Cluster: Chromosome chr6 scaffold_3, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr6 scaffold_3, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 2230
Score = 93.1 bits (221), Expect = 4e-17
Identities = 118/442 (26%), Positives = 174/442 (39%), Gaps = 57/442 (12%)
Query: 471 IFTLLNAKGAVSKVLTCAELHKKAERIG-NLLL-EKGRVNTGDHVALIFPPGLDLICAFY 528
++T +N +G V T ELH A I NLLL +K GD V L++ PGLD I AF+
Sbjct: 489 LYTWINEEGVVVSQRTYRELHANASCIAHNLLLNQKPLFKPGDRVLLVYIPGLDFIDAFF 548
Query: 529 GCLYVGAVPVTIRPPHPQ-NLHTTLPTVRMIVDVSKATLV----LSNQSVIKLLRSKEAS 583
GCL +PV I N L T+R V A L S IK R+
Sbjct: 549 GCLRAKLLPVPIENIAKSCNALAILSTIRYHAGVCAARWPNLPWLHTDSWIKYSRNLLQE 608
Query: 584 NVLDSKAWPMTLDTDDMPKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSL 643
++ D P + L +L F+ +TG G+ ++H +
Sbjct: 609 DIADQSE---------------------PQPDDLCFLQFTSGSTGDAKGVMITHGGLIHN 647
Query: 644 CRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIPPSEVEVNPALWLSA 703
+ M+ + + L Y +G S++ SG ++L P NP LWL
Sbjct: 648 VKLMRRRYKSTSKTVLVSWLPQYHDMGLIGGLFSALVSGGSAVLFSPMSFIKNPLLWLQT 707
Query: 704 VSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVVAEERPRINLTNSFS 763
+S+++ + EL + L S + + + NL+ + ++VA E R N F
Sbjct: 708 MSKFQATHSAGPNFAFELVVRRLESGKDTVHN--YNLSSM-IFLMVAAEPVRQNTLKRFV 764
Query: 764 KLFSALGLSPRAVSTSFGCRVNIAI--CLQGASSPEPSTVYVDLRALRNDRVSLVERGSP 821
KL S GL ++ +G N C G P + VD + ER
Sbjct: 765 KLTSPFGLCEEVLAPGYGLAENCVFVSCAYGEGKP----ILVDWQ----------ER--- 807
Query: 822 HSLCLMESGKLLPGVKVITANPET-KGQCGDSHLGEIWVQSPHNASGYFTIYGDESDYAD 880
+C V + +PET + Q GEIW+ SP GY +G E
Sbjct: 808 --VCCGYVDTENADVDIRVVDPETGEEQEEVGKEGEIWISSPSAGVGY---WGREELSGK 862
Query: 881 HFSAQLVTGNTGEVYARTGYLG 902
F +L + G Y RTG LG
Sbjct: 863 TFRNEL-QNHPGRRYTRTGDLG 883
>UniRef50_Q8XYF2 Cluster: Probable polyketide synthase protein; n=1;
Ralstonia solanacearum|Rep: Probable polyketide synthase
protein - Ralstonia solanacearum (Pseudomonas
solanacearum)
Length = 4268
Score = 92.3 bits (219), Expect = 6e-17
Identities = 94/438 (21%), Positives = 169/438 (38%), Gaps = 26/438 (5%)
Query: 479 GAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPV 538
GA L L ++ R L ++G G ++FP G+D + A C Y G V
Sbjct: 35 GADDLRLGYGALSERVRRCAAALQQRGAA--GSTALILFPSGIDYVVALLACFYAGVTGV 92
Query: 539 TIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKL----LRSKEASNVLDSKAWPMT 594
+ P + LP + I + +VL++ ++ + LR A + LD
Sbjct: 93 PVNLPGVSRVRRVLPKLGDITRDCRPAVVLTHTAIERASGNDLRDFAAGHGLD------I 146
Query: 595 LDTDDMPKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTS----LCRSMKIA 650
L D + + + A T E +A+L ++ +TG G+ H A+ L R +
Sbjct: 147 LHLDTLGGEAAAWVRPALTPESIAFLQYTSGSTGSPKGVVNRHGALLRNLQFLGRLTRPQ 206
Query: 651 CELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIPPSEVEVNPALWLSAVSQYKVR 710
+A L + LG + L + G+ ++ + P +P WL + +
Sbjct: 207 DRAPEDTAVASWLPLFHDLGLIMGILLPLAYGNRAVYMAPMAFVADPLRWLEIATAERAT 266
Query: 711 DTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVVAEERPRINLTNSFSKLFSALG 770
C + LC + ++ GI+L+ V+ C++ A E + +F F+A G
Sbjct: 267 ALPCPSFALRLCADEARRAA-PARTAGIDLSSVQ-CLMPAAEPVLPSQIEAFQAAFAAHG 324
Query: 771 LSPRAVSTSFGCRVNIAICLQGASSPEPSTVYVDLRALRNDRVSLVERGSPHSLC----L 826
+ A+ ++G + P + V+ L R + +P
Sbjct: 325 MRREAIRPAYGLAEATLLVSANVDDAPPHRIDVETAPLEQGRAVVHPAAAPMPAAGRRRY 384
Query: 827 MESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNASGYFTIYGDESDYADHFSAQL 886
+ +G+ G V +P T + +GEIW+ P A GY+ ++++
Sbjct: 385 VSNGREFDGQDVRIVDPRTCATLPEGTVGEIWISGPCIAGGYW----NKAELNREIFMAE 440
Query: 887 VTGNTGEVYARTGYLGFL 904
G Y RTG +GFL
Sbjct: 441 TPGAGDRRYLRTGDMGFL 458
Score = 50.8 bits (116), Expect = 2e-04
Identities = 86/373 (23%), Positives = 142/373 (38%), Gaps = 25/373 (6%)
Query: 29 ETGLWHAVLASVLNGMHVIFIPYALMKVSPASWMHMITKHRASIAIVKSRDLHWGLLATR 88
+ GL +L + G +++ P W+ + T RA+ S L R
Sbjct: 224 DLGLIMGILLPLAYGNRAVYMAPMAFVADPLRWLEIATAERATALPCPSFALRLCADEAR 283
Query: 89 DHKE-----ISLSSLRMLLVADGANPWSLSSCDQFLSVFQSKGVRGDAICPCACSSESMT 143
I LSS++ L+ A A P S + F + F + G+R +AI P +E+ T
Sbjct: 284 RAAPARTAGIDLSSVQCLMPA--AEPVLPSQIEAFQAAFAAHGMRREAIRPAYGLAEA-T 340
Query: 144 VCIXXXXXXXXXXXXXVLSMSGLSYG--VVRVDAENSLTSLTLQ--DCGQVMPSCVIVVV 199
+ + V + L G VV A + + G+ + +V
Sbjct: 341 LLVSANVDDAPPHRIDV-ETAPLEQGRAVVHPAAAPMPAAGRRRYVSNGREFDGQDVRIV 399
Query: 200 KMEGPAYLCKTDEVGEICVLSGATGSGYWGLPGLTNTVFRVRPLDSDGEPIGEEHYVRSX 259
A L + VGEI + GYW L +F ++ G G+ Y+R+
Sbjct: 400 DPRTCATLPE-GTVGEIWISGPCIAGGYWNKAELNREIFMA---ETPGA--GDRRYLRTG 453
Query: 260 XXXXXXXXXXXXXXXSRDGLMTVTGRKHNMDDIIATVLAVEPMKFIYRGRIAVFSVRVLR 319
+D +M G+ H +DI AT G A FS++
Sbjct: 454 DMGFLHGGHLFVTGRLKD-MMLFRGQCHYPNDIEATSGRAHAAAIPESG--AAFSIQAED 510
Query: 320 D--ERICIVAEQRPDCGEEESFQWMSRVLQAVDSIHQVGIYCLALVQPNFLPKTPLGGIH 377
+ ER+ IV E R G + + V AV H +G++ + L++ LP+T G +
Sbjct: 511 EAGERLVIVQEVRKQAGIDPR-DIATAVRAAVAEGHALGVHAVVLIRKGTLPRTTSGKVR 569
Query: 378 LSECKRRFLEGTL 390
+ + +L GTL
Sbjct: 570 RAAVREAWLAGTL 582
>UniRef50_A4ZPY1 Cluster: DepA; n=2; Betaproteobacteria|Rep: DepA -
Chromobacterium violaceum
Length = 1697
Score = 91.9 bits (218), Expect = 8e-17
Identities = 109/451 (24%), Positives = 179/451 (39%), Gaps = 42/451 (9%)
Query: 455 ISQILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVA 514
I++ L WRA+++ D + + +A + L+ A L ++A I L + TGD V
Sbjct: 32 IARQLLWRAEASPDRLAYA--SADPVKNIALSYAGLCERASGIAARLAQA--TETGDRVM 87
Query: 515 LIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVI 574
L++ LD + AF+GC G +PV + P H ++ T+ I + A + L
Sbjct: 88 LVYQEPLDFLPAFFGCCLAGVIPVPVAPRHGRD------TMLAIAEDCGAVIAL------ 135
Query: 575 KLLRSKEASNVLDSKAWPMTLDTDDMPKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIK 634
+ EA + L W T +T+ P + RA L ++ +T G+
Sbjct: 136 ----TAEARDALPGLRWMRTDETEG----AAPFL-RAAGEGSPVLLQYTSGSTRTPQGVV 186
Query: 635 MSHAAVTSLCRSMKIACELYPSRHIALCLDPYC-GLGFALWCLSSIYSGHHSILIPPSEV 693
++ + + + ++ + + + PY +G L+ + G + L+ P +
Sbjct: 187 VTQTGLWATIEDLDRGA-MHDADSVMISWLPYFHDMGLVYGILTPLQCGFPAYLMAPEKF 245
Query: 694 EVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVVAEER 753
P WL A+ + T LC + G +L+ +R + AE
Sbjct: 246 VAQPMSWLRAIEARRGTHTAAPNFAYALCADRAAD-----LAPGTDLSSLRYALNGAEP- 299
Query: 754 PRINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPSTVYVDLRALRNDRV 813
R + F F+ GL P V+ +G G V AL RV
Sbjct: 300 VRCDTVRRFEAAFAPFGLKPSVVAPGYGLAEATLKVTAGRCGEGTRGVRFGRDALARGRV 359
Query: 814 SLVERGSPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNASGYFTIYG 873
S G + C G L +V NP+T+ C +GEIWV A Y+
Sbjct: 360 SPEADGVELAAC----GSSLIDTRVRIVNPDTREPCEADVVGEIWVSGSTVADSYWR-RP 414
Query: 874 DESDYADHFSAQLVTGNTGEVYARTGYLGFL 904
+ES + F A+L N V+ RTG LGFL
Sbjct: 415 EES--REIFGARLADDN--GVWLRTGDLGFL 441
Score = 58.4 bits (135), Expect = 1e-06
Identities = 84/374 (22%), Positives = 139/374 (37%), Gaps = 23/374 (6%)
Query: 20 MVCVLDFKRETGLWHAVLASVLNGMHVIFIPYALMKVSPASWMHMITKHRASIAIVKSRD 79
M+ L + + GL + +L + G + P SW+ I R + +
Sbjct: 211 MISWLPYFHDMGLVYGILTPLQCGFPAYLMAPEKFVAQPMSWLRAIEARRGTHTAAPN-- 268
Query: 80 LHWGLLATRDHK---EISLSSLRMLLVADGANPWSLSSCDQFLSVFQSKGVRGDAICPCA 136
+ L A R LSSLR L +GA P + +F + F G++ + P
Sbjct: 269 FAYALCADRAADLAPGTDLSSLRYAL--NGAEPVRCDTVRRFEAAFAPFGLKPSVVAPGY 326
Query: 137 CSSESMTVCIXXXXXXXXXXXXXVLSMSGLSYGVVRVDAENSLTSLTLQDCGQVMPSCVI 196
+E+ T+ + L+ G V +A+ + L CG + +
Sbjct: 327 GLAEA-TLKVTAGRCGEGTRGVR-FGRDALARGRVSPEADG----VELAACGSSLIDTRV 380
Query: 197 VVVKMEGPAYLCKTDEVGEICVLSGATGSGYWGLPGLTNTVFRVRPLDSDGEPIGEEHYV 256
+V + C+ D VGEI V YW P + +F R D +G ++
Sbjct: 381 RIVNPD-TREPCEADVVGEIWVSGSTVADSYWRRPEESREIFGARLADDNGV------WL 433
Query: 257 RSXXXXXXXXXXXXXXXXSRDGLMTVTGRKHNMDDIIATVLAVEPMKFIYRGRIAVFSVR 316
R+ +D L+ V GR D+ TV A P I GR+ +V
Sbjct: 434 RTGDLGFLYDGDLFVTSRLKD-LIIVGGRNFYSHDLEDTVSACHPS--IRMGRVFAAAVD 490
Query: 317 VLRDERICIVAEQRPDCGEEESFQWMSRVLQAVDSIHQVGIYCLALVQPNFLPKTPLGGI 376
E + I AE R C E ++ + + + A+ H V +AL++ + +T G
Sbjct: 491 GEEGEGVLIGAEVRGGCEEADAREILPVIRAALAREHGVAPARVALLRRGSILRTSSGKT 550
Query: 377 HLSECKRRFLEGTL 390
S + L G L
Sbjct: 551 RRSATRDALLRGEL 564
Score = 38.7 bits (86), Expect = 0.84
Identities = 24/61 (39%), Positives = 32/61 (52%), Gaps = 1/61 (1%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPH 544
L+ EL ++AE I L + G V GD VA I PG + A G + GAV ++I P
Sbjct: 1124 LSYGELLRQAEDIAGALRQSG-VARGDVVAAIVAPGPRAVAALLGIVMAGAVYLSIEPSW 1182
Query: 545 P 545
P
Sbjct: 1183 P 1183
>UniRef50_A4KUB2 Cluster: TlmVI; n=1; Streptoalloteichus
hindustanus|Rep: TlmVI - Streptoalloteichus hindustanus
Length = 2742
Score = 91.5 bits (217), Expect = 1e-16
Identities = 115/476 (24%), Positives = 192/476 (40%), Gaps = 48/476 (10%)
Query: 446 SDAARKYQFISQILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKG 505
S AR + I + R A++T + L S+ A + +A I L E+G
Sbjct: 3 STRARSARTIVDVARHHAETTPSRPAYVFLPDGETESERFDFAGIDLRARAIAVALRERG 62
Query: 506 RVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKAT 565
V G+ V + +P G + A GCLY GA+ V P + V + T
Sbjct: 63 MV--GERVLIAYPSGSAYVQAILGCLYAGAIAVPCDAPERAS------------SVERLT 108
Query: 566 LVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKKLPIMYRAPTAEM--LAYLDFS 623
V + + L + + + +T +D+ + + APT ++ A+L ++
Sbjct: 109 AVAGDAAPALTLAAADGPLAGRMPLFDITTVSDEAAES-----WSAPTLDVDAPAFLQYT 163
Query: 624 VSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGH 683
+T G+ +SHA + + +++ C L + +G L ++ G
Sbjct: 164 SGSTRTPRGVMVSHANLLANEEAIRRTCGHDQDSTFVGWLPLFHDMGLVANVLQPLFLGS 223
Query: 684 HSILIPPSEVEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACV 743
S+L+PPS V +P WL AV++Y+ + ELC + +S + ++ V
Sbjct: 224 LSVLMPPSAVLRHPIRWLRAVTRYRAHTSGGPNFGYELCVE--RTSPEERAELDLSSWLV 281
Query: 744 RTCVVVAEERPRINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPE-PSTVY 802
E R F+++F+ G + A +G + + G E P +
Sbjct: 282 ---AYNGAEPVRAATLRRFAEVFTPHGFASTAHFPCYGL-AEATLLVSGTPKAEAPLVLT 337
Query: 803 VDLRALRNDRVSLVERGSPHSLC--------------LMESGKLLPGVKVITANPETKGQ 848
VD LR RV+ +P + L+ GK+ +V +PET
Sbjct: 338 VDPAELRQGRVTPAVEPAPGTESVGTGSLGTGSLGTELVSCGKVAVDTEVRVVDPETARP 397
Query: 849 CGDSHLGEIWVQSPHNASGYFTIYGDESDYADHFSAQLVTGNTGEVYARTGYLGFL 904
D +GE+WV+ P + GY+ DESD H A+L G G Y RTG LG L
Sbjct: 398 VADGQVGEVWVRGPGVSGGYWR-DPDESDKVMH--ARL--GEEGP-YLRTGDLGCL 447
Score = 52.8 bits (121), Expect = 5e-05
Identities = 84/404 (20%), Positives = 146/404 (36%), Gaps = 29/404 (7%)
Query: 1 MLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLASVLNGMHVIFIPYALMKVSPAS 60
+LA+ + C + + V L + GL VL + G + +P + + P
Sbjct: 180 LLANEEAIRRTCGHDQDSTFVGWLPLFHDMGLVANVLQPLFLGSLSVLMPPSAVLRHPIR 239
Query: 61 WMHMITKHRASIAIVKSRDLHWGLLATRDHKEISLSSLRMLLVADGANPWSLSSCDQFLS 120
W+ +T++RA + + + T + L L+ +GA P ++ +F
Sbjct: 240 WLRAVTRYRAHTSGGPNFGYELCVERTSPEERAELDLSSWLVAYNGAEPVRAATLRRFAE 299
Query: 121 VFQSKGVRGDAICPCACSSESMTVCIXXXXXXXXXXXXXV----LSMSGLSYGVVRVDAE 176
VF G A PC +E+ T+ + V L ++ V
Sbjct: 300 VFTPHGFASTAHFPCYGLAEA-TLLVSGTPKAEAPLVLTVDPAELRQGRVTPAVEPAPGT 358
Query: 177 NSLTS---------LTLQDCGQVMPSCVIVVVKMEGPAYLCKTDEVGEICVLSGATGSGY 227
S+ + L CG+V + VV E A +VGE+ V GY
Sbjct: 359 ESVGTGSLGTGSLGTELVSCGKVAVDTEVRVVDPE-TARPVADGQVGEVWVRGPGVSGGY 417
Query: 228 WGLPGLTNTVFRVRPLDSDGEPIGEEH-YVRSXXXXXXXXXXXXXXXXSRDGLMTVTGRK 286
W P ++ V R +GEE Y+R+ +D L+ V G+
Sbjct: 418 WRDPDESDKVMHAR--------LGEEGPYLRTGDLGCLLDGQLYLTGRRKD-LLVVRGQN 468
Query: 287 HNMDDIIATVLAVEPMKFIYRGRIAVFSVRVLRDERICIVAEQRPDCGEEESFQWMSRVL 346
H D+ T P G A F+V ER+ + E R + V
Sbjct: 469 HYPHDLEWTAEQAHPALRPSCG--AAFAVDDGDRERLVLCYELRAPVSDLADVA--EAVR 524
Query: 347 QAVDSIHQVGIYCLALVQPNFLPKTPLGGIHLSECKRRFLEGTL 390
+ + H + + L ++ +PKT G + C++ +++G L
Sbjct: 525 RELSRRHGIEPHELVFLERGGVPKTTSGKVRRQSCRQSYVDGKL 568
>UniRef50_A4JL36 Cluster: AMP-dependent synthetase and ligase; n=1;
Burkholderia vietnamiensis G4|Rep: AMP-dependent
synthetase and ligase - Burkholderia vietnamiensis
(strain G4 / LMG 22486) (Burkholderiacepacia (strain
R1808))
Length = 598
Score = 91.5 bits (217), Expect = 1e-16
Identities = 108/472 (22%), Positives = 180/472 (38%), Gaps = 22/472 (4%)
Query: 448 AARKYQFISQILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRV 507
A R + +LR RA+ T + V F L + A + +LL++
Sbjct: 12 AERTTSSLLHVLRERAEHTPERVAFHFLRDGEDDVASWPYGQFAAAAAHVRDLLVQHALH 71
Query: 508 NTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLV 567
V L+ PGL + A +G L GA V PP ++
Sbjct: 72 ER--RVLLVLEPGLGYVAALFGILLAGATAVPSFPPAGSRAVARFASICRDAHPDVVIAG 129
Query: 568 LSNQSVIKLL-RSKEASNVLDSKAW--PMTLDTDDMPKKKLP-IMYRAPTAEMLAYLDFS 623
++S+ + L R + + V + D D ++ + E A L ++
Sbjct: 130 KQHRSLQQELDRLHDGARVAPALLTIDEHAFDAIDASAHDFGRVLEQGLDLERPALLQYT 189
Query: 624 VSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGH 683
+TG G+ ++H + S C + P R L PY +G L +++SG
Sbjct: 190 SGSTGEPKGVVVTHRNLVSNCAVIAERLGADPERVGCTWLPPYHDMGLMGALLLAVFSGF 249
Query: 684 HSILIPPSEVEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACV 743
+++ P P WL A+S Y+V + +LC ++ ++ ++L +
Sbjct: 250 PLVILSPQHFVQRPYRWLKAISDYRVTTSVAPNFAFDLCV----DHISDEEAATLDLGSL 305
Query: 744 RTCVVVAEERPRINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPST-VY 802
+ AE L F+ F G RAV +G + + G P T +
Sbjct: 306 QHVFCGAEPVSHATL-ERFAARFGRHGFERRAVVPCYG-MAEATLYVSGKPGRSPITLID 363
Query: 803 VDLRALRNDRVSLVERGSP--HSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQ 860
VD AL + + S L+ G + G +++ +P TK + +GEIW
Sbjct: 364 VDKEALARGQCVPHDAQSDLLGRTTLVGCGPVAAGHRLLIVDPATKRVLPERSIGEIWFS 423
Query: 861 SPHNASGYFTIYGDESDYADHFSAQLV--TGNTGEV-YARTGYLGFLRRTEI 909
P+ A+GY +D D F+A L G+ Y RTG LGFL E+
Sbjct: 424 GPNVAAGYL----GRADSDDVFAAALCDERGDADSARYLRTGDLGFLNHGEL 471
Score = 58.0 bits (134), Expect = 1e-06
Identities = 83/368 (22%), Positives = 145/368 (39%), Gaps = 16/368 (4%)
Query: 29 ETGLWHAVLASVLNGMHVIFIPYALMKVSPASWMHMITKHRASIAIVKSR--DLHWGLLA 86
+ GL A+L +V +G ++ + P W+ I+ +R + ++ + DL ++
Sbjct: 234 DMGLMGALLLAVFSGFPLVILSPQHFVQRPYRWLKAISDYRVTTSVAPNFAFDLCVDHIS 293
Query: 87 TRDHKEISLSSLRMLLVADGANPWSLSSCDQFLSVFQSKGVRGDAICPCACSSESMTVCI 146
+ + L SL+ + GA P S ++ ++F + F G A+ PC +E+ T+ +
Sbjct: 294 DEEAATLDLGSLQHVFC--GAEPVSHATLERFAARFGRHGFERRAVVPCYGMAEA-TLYV 350
Query: 147 XXXXXXXXXXXXXVLSMSGLSYG-VVRVDAENSLTS-LTLQDCGQVMPSCVIVVVKMEGP 204
V L+ G V DA++ L TL CG V +++V
Sbjct: 351 SGKPGRSPITLIDV-DKEALARGQCVPHDAQSDLLGRTTLVGCGPVAAGHRLLIVDPATK 409
Query: 205 AYLCKTDEVGEICVLSGATGSGYWGLPGLTNTVFRVRPLDSDGEPIGEEHYVRSXXXXXX 264
L + +GEI +GY G ++ VF D G+ Y+R+
Sbjct: 410 RVLPER-SIGEIWFSGPNVAAGYLGRAD-SDDVFAAALCDERGD-ADSARYLRTGDLGFL 466
Query: 265 XXXXXXXXXXSRDGLMTVTGRKHNMDDIIATVLAVEPMKFIYRGRIAVFSVRVLRDERIC 324
+D ++ V GR DI +V A I + FS+ E +
Sbjct: 467 NHGELFVTGRIKD-VVIVAGRNLYPTDIEGSVQAAHDA--IRTNGVVAFSIDGGPRESLV 523
Query: 325 IVAEQRPD--CGEEESFQWMSRVLQAVDSIHQVGIYCLALVQPNFLPKTPLGGIHLSECK 382
IVAE + E+ + + + AV H V + L +P T G + CK
Sbjct: 524 IVAELKRSRRLSPEQMGEVRAAITLAVTRDHGVAPAVVHLGPMGAIPLTTSGKVRRQACK 583
Query: 383 RRFLEGTL 390
+ F +G+L
Sbjct: 584 QAFQQGSL 591
>UniRef50_Q8NLR6 Cluster: Acyl-CoA synthetases
(AMP-forming)/AMP-acid ligases II; n=6;
Corynebacterium|Rep: Acyl-CoA synthetases
(AMP-forming)/AMP-acid ligases II - Corynebacterium
glutamicum (Brevibacterium flavum)
Length = 596
Score = 90.6 bits (215), Expect = 2e-16
Identities = 77/390 (19%), Positives = 168/390 (43%), Gaps = 16/390 (4%)
Query: 510 GDHVALIFPPGLDLICAFYGCLYVGAVPVTI----RPPHPQNLHTTLPTVRMIVDVSKAT 565
GD A++ + I +F G +Y G VPV + P H +L+ +V ++ +
Sbjct: 62 GDRAAILANNSPEYIFSFLGAIYAGMVPVPLYDPNEPGHADHLNAVFADSEPVVVLTNSK 121
Query: 566 LVLSNQSVIKLLRSKEASNVLDSKAWPMTL-DTDDMPK-----KKLPIMYRAPTAEMLAY 619
+ + L + E +L + P +L D+ + P ++L + ++ ++ A+
Sbjct: 122 SAGAVRKHFSSLPAAERPRILSVDSLPDSLADSYENPMLTEAGRRLAALRQSAPIDLTAF 181
Query: 620 LDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSI 679
L ++ +T AG+ +++ ++ + + A +L + L + +G L ++
Sbjct: 182 LQYTSGSTRTPAGVVLTNRSILTNVLQIFSAAQLKTPLRLVSWLPLHHDMGIILAAFVTM 241
Query: 680 YSGHHSILIPPSEVEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSS-VNQLKSKGI 738
+ + P V+ P+ W+ +++ + Y V+ L + + + +
Sbjct: 242 LGLDNEFMNPRDFVQ-QPSRWIKQLNRRESDVDVNVYTVVPNFALELAARYAKPAEGETL 300
Query: 739 NLACVRTCVVVAEERPRINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEP 798
+L+ + +++ E N +F + F GL + + S+G + + P
Sbjct: 301 DLSAL-DAIIIGSEPVTENALTTFREAFEPYGLPVQTLRPSYGLAEASLLVTTPQTENRP 359
Query: 799 STVYVDLRALRNDRVSLVERGSPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIW 858
Y D AL +RV LVE+G+ ++ + +G++ +++ + ET + D +GEIW
Sbjct: 360 LISYFDREALAENRVELVEKGNNKAVAFVSNGQVAAPQQLVIVDSETGTELADGQIGEIW 419
Query: 859 VQSPHNASGYFTIYGDESDYADHFSAQLVT 888
+ A+GY E D A+ F +L T
Sbjct: 420 THGENTAAGYL---DREEDTAETFRNRLTT 446
>UniRef50_Q7X541 Cluster: Acyl-CoA synthase; n=1; Actinoplanes
friuliensis|Rep: Acyl-CoA synthase - Actinoplanes
friuliensis
Length = 588
Score = 90.6 bits (215), Expect = 2e-16
Identities = 111/464 (23%), Positives = 186/464 (40%), Gaps = 28/464 (6%)
Query: 450 RKYQFISQILRWRAQSTSDH---VIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGR 506
R + I +LR ++T D T L+ V+ LT AEL ++A +
Sbjct: 5 RTAESIPAVLRKSVENTPDRGASAFVTHLDDPTGVAW-LTYAELDRRARAAA--VQFSAH 61
Query: 507 VNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATL 566
GD + L+ P G D + A GCLY G V V P P +R+I +
Sbjct: 62 AAPGDRMLLLHPAGPDFLIALLGCLYAGLVAVP--SPLPGRYAHQRRRLRLIAADADVAA 119
Query: 567 VLSNQSVIKLLRSKEASNVLDSKAWPMTLD-TDDMPKKKLPIMYRAPTAEMLAYLDFSVS 625
VL+ + A L + +TLD T D P + + + +A L ++
Sbjct: 120 VLTAGESRDEVTGWAAEQELGAVP-VLTLDGTADADAWTPPPL----SQDTVAVLQYTSG 174
Query: 626 TTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHS 685
+TG G+ + H + ++ + P + L + +G L + +G S
Sbjct: 175 STGDPKGVVIDHGNILHNAATIIAVTGMRPGYAVGGWLPHFHDMGLMGLLLPPLLAGSAS 234
Query: 686 ILIPPSEVEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRT 745
++ P P LWL + ++ + + +LC + V + G++L+ R
Sbjct: 235 VMTSPMAFLKRPLLWLQMIDRFNIEISAAPDFAYDLCV----AKVTDAQLAGVDLSRWRV 290
Query: 746 CVVVAEERPRINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPSTVYVDL 805
+ E R + F + F+A GL P AV+ SFG + + GA + D
Sbjct: 291 -AIDGSEPVRAAVLTRFQERFAAAGLRPEAVTPSFG-MAEATLFVSGAPDTPFVIRHADT 348
Query: 806 RALRNDRVSLVERGSPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNA 865
L+ + P ++ G + V+V +P++ D +GEIW++ P
Sbjct: 349 DLLQRNEFRPATGDRP-GRDVVSCGAPV-DVEVRIVDPDSTEVLADGQVGEIWLRGPSIG 406
Query: 866 SGYFTIYGDESDYADHFSAQLVTGNTGEVYARTGYLGFLRRTEI 909
GY +G ++ A F A TG+ G Y RTG LG L E+
Sbjct: 407 RGY---WGRDAGTAG-FGAVTSTGDGG--YLRTGDLGTLFEGEL 444
>UniRef50_A0G714 Cluster: AMP-dependent synthetase and ligase; n=1;
Burkholderia phymatum STM815|Rep: AMP-dependent
synthetase and ligase - Burkholderia phymatum STM815
Length = 962
Score = 88.6 bits (210), Expect = 8e-16
Identities = 99/428 (23%), Positives = 173/428 (40%), Gaps = 22/428 (5%)
Query: 447 DAARKYQFISQILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGR 506
D A + + L+W A + LL+ + A +T A LH+ A R+ L + G
Sbjct: 127 DPAADAGTLVEALQWHASRRPERTHIVLLD-EDAAPHAMTYAALHEAALRVSRGLRQIG- 184
Query: 507 VNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPP-HPQNLHTTLPTVRMIVDVSKAT 565
VN GD VAL+ P G D F G L +GA+ V + PP + L I+ ++A
Sbjct: 185 VNPGDTVALMLPTGSDYFACFAGILLLGAIVVPVYPPAQSARIDDHLARHAAILSDARAR 244
Query: 566 LVL--SNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKKLPIMYRAPTAEMLAYLDFS 623
+++ S+ V ++ + + A P + D + P AE +A L ++
Sbjct: 245 VMIVPSHAFVAGVMAKARIPTLHEIVAVPQLMGEMDAEQ-------YVPRAEDVALLQYT 297
Query: 624 VSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGH 683
+TG G+ ++HA + + R+M + L Y +G +Y G
Sbjct: 298 SGSTGTPKGVVLTHANLLANIRAMGHTALIEEHDVFVSWLPLYHDMGLIGAWFGPLYFGI 357
Query: 684 HSILIPPSEVEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACV 743
+L+ P PA WL A+S Y T E C + V+ + ++L+ +
Sbjct: 358 PLVLMSPLTFLARPARWLHAISDYHATITAAPNFAYERCAR----RVDDTDLEDVDLSSL 413
Query: 744 RTCVVVAEERPRINLTNSFSKLFSALGLSPRAVSTSFGCRVN-IAICLQGASSPEPSTVY 802
R AE + +F+ F+ G A++ +G N + + +
Sbjct: 414 RLAFCGAEPVSAATM-RAFASRFARNGFRHTALTPVYGLAENTLGLAFSEPGRGVRTDCI 472
Query: 803 VDLRALRNDRVSLVERGSPHS-LCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQS 861
+R + R + E SP L L+ G+ LP ++ + + + + +G I +S
Sbjct: 473 SRVRLADSQRAAPAE--SPDEVLELVSCGRALPRNQIRIMDAD-GNEVSERAVGRIEFRS 529
Query: 862 PHNASGYF 869
P GYF
Sbjct: 530 PSATRGYF 537
Score = 47.6 bits (108), Expect = 0.002
Identities = 58/238 (24%), Positives = 96/238 (40%), Gaps = 12/238 (5%)
Query: 1 MLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLASVLNGMHVIFIPYALMKVSPAS 60
+LA+ R + E + V L + GL A + G+ ++ + PA
Sbjct: 314 LLANIRAMGHTALIEEHDVFVSWLPLYHDMGLIGAWFGPLYFGIPLVLMSPLTFLARPAR 373
Query: 61 WMHMITKHRASIAIVKSRDLHWGLLATR----DHKEISLSSLRMLLVADGANPWSLSSCD 116
W+H I+ + A+ I + + + A R D +++ LSSLR+ GA P S ++
Sbjct: 374 WLHAISDYHAT--ITAAPNFAYERCARRVDDTDLEDVDLSSLRLAFC--GAEPVSAATMR 429
Query: 117 QFLSVFQSKGVRGDAICPCACSSESMTVCIXXXXXXXXXXXXXVLSMSGLSYGVVRVDAE 176
F S F G R A+ P +E+ T+ + +S L+ AE
Sbjct: 430 AFASRFARNGFRHTALTPVYGLAEN-TLGL-AFSEPGRGVRTDCISRVRLADSQRAAPAE 487
Query: 177 NSLTSLTLQDCGQVMPSCVIVVVKMEGPAYLCKTDEVGEICVLSGATGSGYWGLPGLT 234
+ L L CG+ +P I ++ +G VG I S + GY+ P LT
Sbjct: 488 SPDEVLELVSCGRALPRNQIRIMDADGNE--VSERAVGRIEFRSPSATRGYFQNPNLT 543
>UniRef50_Q0LNS7 Cluster: Amino acid adenylation; n=1; Herpetosiphon
aurantiacus ATCC 23779|Rep: Amino acid adenylation -
Herpetosiphon aurantiacus ATCC 23779
Length = 4101
Score = 87.8 bits (208), Expect = 1e-15
Identities = 103/466 (22%), Positives = 194/466 (41%), Gaps = 35/466 (7%)
Query: 455 ISQILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVA 514
+ ++LR A++T D VI + A + ++ EL++ ++ +G L G ++TG V
Sbjct: 15 LPELLRTAAETTPDQVIIHI--AAAGNERSISYHELYRSSQAVGQTLRRSG-LSTGQVVL 71
Query: 515 LIFPPGLDLICAFYGCLYVGAVPVTI--RPPHPQNLHTTLPTVRMIVD--VSKATLVLSN 570
+ +D + F+G L+ G VP + P + +L ++V+ V ++ + L+
Sbjct: 72 IALESSVDFLVGFWGALFAGLVPAPLAAEPKRILAIWQSLEQPALLVNHAVGESIIALAE 131
Query: 571 QSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKKLPIMYRAPTAEM----LAYLDFSVST 626
Q ++E LD W + K+ + + + LAYL FS +
Sbjct: 132 QLAPPAQLAQERPTALDGP-WTTAVQLFSPITKRHRSGHISAEGSVQPHDLAYLQFSSGS 190
Query: 627 TGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSI 686
TG G+++SHA + + M AC + + + Y +G L + +G +
Sbjct: 191 TGQPRGVELSHAGLLANLYQMGSACAINSQDSVVSWMPYYHDMGLIAAHLLPLAAGIKQV 250
Query: 687 LIPPSEVEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTC 746
I PA+WL Q++ + ++L + V + G++L CVR
Sbjct: 251 KIDEFYFARRPAIWLEITHQHQASLLTAAPFALDLVNR----RVKPAQLVGLDLRCVRLL 306
Query: 747 VVVAEERPRINLTNSFSKLFSALGLSPRAVSTSFG-CRVNIAICLQGASSPEPSTVYVDL 805
+V AE + +F + GLSP+ + +G + + L + +T +++
Sbjct: 307 IVGAEPIVAAS-CRAFLAQLAPTGLSPQVLLPVYGLAEACVGVSLSPLGT-GMTTHHINR 364
Query: 806 RALRND-RVSLVERGSPHS---------LCLMESGKLLPGVKVITANPETKGQCGDSHLG 855
L ++ R S + HS L L++ G +P +V + + K GD +G
Sbjct: 365 HILLHEARASSPDENQHHSTDPIDQTDWLELVDVGLPIPDCRVRIVDDQDK-LLGDDLIG 423
Query: 856 EIWVQSPHNASGYFTIYGDESDYADHFSAQLVTGNTGEVYARTGYL 901
I V GY+ + + D + L TG+ G + R G L
Sbjct: 424 HIQVSGSQLMRGYYRSNDPSAAFCDGW---LRTGDLG--FLRNGRL 464
Score = 43.2 bits (97), Expect = 0.039
Identities = 42/167 (25%), Positives = 70/167 (41%), Gaps = 9/167 (5%)
Query: 477 AKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAV 536
A A ++LT A+L A ++ LL G VAL+ PG+ I G L+ G
Sbjct: 2672 AVNADGQLLTYAQLASYAAQVAIWLLANG-AGPNQPVALLTQPGIASIVGMVGALWAGVP 2730
Query: 537 PVTIRPPHP-QNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTL 595
+ + P +P LH L L+ NQ+ L+ ++++ W L
Sbjct: 2731 WLGLNPDYPLAQLHDQL------TQAGVQRLLHHNQTHQTALQLQQSAMPQLQLGWLDQL 2784
Query: 596 DTDDMPKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTS 642
+P + PT LAY+ F+ +TG G+ ++H A+ +
Sbjct: 2785 IQQVTALTSMPSI-ATPTPTDLAYVIFTSGSTGRPKGVPITHGALAN 2830
Score = 39.1 bits (87), Expect = 0.63
Identities = 33/136 (24%), Positives = 59/136 (43%), Gaps = 4/136 (2%)
Query: 1 MLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLASVLNGMHVIFIPYALMKVSPAS 60
+LA+ + AC + +V + + + GL A L + G+ + I PA
Sbjct: 204 LLANLYQMGSACAINSQDSVVSWMPYYHDMGLIAAHLLPLAAGIKQVKIDEFYFARRPAI 263
Query: 61 WMHMITKHRASI--AIVKSRDLHWGLLATRDHKEISLSSLRMLLVADGANPWSLSSCDQF 118
W+ + +H+AS+ A + DL + + L +R+L+V GA P +SC F
Sbjct: 264 WLEITHQHQASLLTAAPFALDLVNRRVKPAQLVGLDLRCVRLLIV--GAEPIVAASCRAF 321
Query: 119 LSVFQSKGVRGDAICP 134
L+ G+ + P
Sbjct: 322 LAQLAPTGLSPQVLLP 337
>UniRef50_Q45R86 Cluster: Acyl-CoA ligase; n=2; Streptomyces|Rep:
Acyl-CoA ligase - Streptomyces fradiae
Length = 732
Score = 87.0 bits (206), Expect = 2e-15
Identities = 100/390 (25%), Positives = 163/390 (41%), Gaps = 23/390 (5%)
Query: 488 AELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQN 547
A L A RI LL G + TG V L+FP + A+ GCLY G V V P P
Sbjct: 93 AWLDDTARRIAVLLRAAG-LETGARVLLLFPQSAEFAAAYAGCLYAGMVAVPA--PLPTG 149
Query: 548 LHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKKLPI 607
V I S+A VL+ +R A L A P+ D++P P
Sbjct: 150 TSHEAARVVGIAKDSEAGAVLTVSETEADVRQWAARTGLG--ALPLHC-VDELPGDADPD 206
Query: 608 MYRAPT--AEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIALCLDP 665
+R P A+ +A L ++ +TG G+ ++H A+ RS+ +L + L
Sbjct: 207 TWREPEIRADTVAVLQYTSGSTGSPKGVVVTHGALADNVRSLLTGFDLGSGARLGGWLPM 266
Query: 666 YCGLGFALWCLSSIYSGHHSILIPPSEVEVNPALWLSAVSQYKVRDTFCSYGVMELCTKG 725
Y +G +++SG ++L+ S P+ WL + ++ + + + C +
Sbjct: 267 YHDMGLFGLLSPALFSGGAAVLMSGSAFLRRPSQWLRLIDRFGLVFSAAPDFAYDYCVR- 325
Query: 726 LGSSVNQLKSKGINLACVRTCVVVAEERPRINLTNSFSKLFSALGLSPRAVSTSFGCRVN 785
V ++ G++L+ R E R +F+K F+ GL P A + +G +
Sbjct: 326 ---RVRPEETDGLDLSRWR-WAANGSEPIRAETLRAFAKEFAPAGLHPNATTPCYG--LA 379
Query: 786 IAICLQGASSPEPSTVYVDLRALRNDRVSLVERGSPHSLCLMESGKLLPGVKVITANPET 845
A L + E T VD+ L N R G P S ++ G+ P +++ +P T
Sbjct: 380 EATLLVSLPTGELRTRRVDVAELENHRFVEAAVGRP-SREIVSCGR-PPSLEIRVVDPAT 437
Query: 846 KGQ------CGDSHLGEIWVQSPHNASGYF 869
G++ +GEI V+ A GY+
Sbjct: 438 GKSVTGGDGAGETRVGEIRVRGASVARGYW 467
Score = 37.1 bits (82), Expect = 2.6
Identities = 47/229 (20%), Positives = 82/229 (35%), Gaps = 14/229 (6%)
Query: 24 LDFKRETGLWHAVLASVLNGMHVIFIPYALMKVSPASWMHMITKHRASIAIVKSRDLHWG 83
L + GL+ + ++ +G + + + P+ W+ +I + + +
Sbjct: 264 LPMYHDMGLFGLLSPALFSGGAAVLMSGSAFLRRPSQWLRLIDRFGLVFSAAPDFAYDYC 323
Query: 84 LLATRDHKEISLSSLRMLLVADGANPWSLSSCDQFLSVFQSKGVRGDAICPCACSSESMT 143
+ R + L R A+G+ P + F F G+ +A PC +E+ T
Sbjct: 324 VRRVRPEETDGLDLSRWRWAANGSEPIRAETLRAFAKEFAPAGLHPNATTPCYGLAEA-T 382
Query: 144 VCIXXXXXXXXXXXXXVLSMSGLSYGVVRVDAENSLTSLTLQDCGQVMPSCVIVVVKMEG 203
+ + V + + V+A S + CG+ PS I VV
Sbjct: 383 LLVSLPTGELRTRRVDVAELENHRF----VEAAVGRPSREIVSCGRP-PSLEIRVVDPAT 437
Query: 204 PAYLCKTD-----EVGEICVLSGATGSGYWGLPGLTNTVFRVRPLDSDG 247
+ D VGEI V + GYW P T F +D+DG
Sbjct: 438 GKSVTGGDGAGETRVGEIRVRGASVARGYWQKPEATAETF---VMDADG 483
>UniRef50_Q09773 Cluster: Meiotically up-regulated gene 62 protein;
n=1; Schizosaccharomyces pombe|Rep: Meiotically
up-regulated gene 62 protein - Schizosaccharomyces pombe
(Fission yeast)
Length = 1428
Score = 86.6 bits (205), Expect = 3e-15
Identities = 96/465 (20%), Positives = 182/465 (39%), Gaps = 27/465 (5%)
Query: 455 ISQILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVA 514
I L+ ++ T NA LT A K + + H+
Sbjct: 802 ILDFLKTKSAKTPTSPAILTFNAIEKTKVELTWAHFELKVASHVEYMQLSVKAKARSHIL 861
Query: 515 LIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVI 574
L++ L+ + + + C ++G +P+ + L + I +L + V+
Sbjct: 862 LLYYDPLEFLISIHSCFHLGVIPIPFQIREISQLIGEIEEFTKIAKAFNVEAILVDHKVL 921
Query: 575 KLLRSKEASNV-------LDSKAWPMTLDTDDMP-----KKKLPIMYRAPTAEM--LAYL 620
L+S++ SN L+ KA P +T +P KK L ++ +A +
Sbjct: 922 ISLKSRDISNHFQQTCIDLNMKA-PKIFETTGIPISKRAKKALNLITPGELNNKGKVALI 980
Query: 621 DFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIY 680
+ G + + SH+++ + C K + I ++ G+G L +Y
Sbjct: 981 SINKLEDGSIIPTQFSHSSLLAFCHEQKEFVIGNEEKPIIGGIEFSSGMGLLHTALLGVY 1040
Query: 681 SGHHSILIPPSEVEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINL 740
+G ++LI + N +L A+ Q + + +C K S+ S IN
Sbjct: 1041 AGVPTLLIKQENLCNNGSLLFEAIEQNSLSKVMIP---LNICQKSF-STAQGCNSIVIN- 1095
Query: 741 ACVRTCVVVAEERPRINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPST 800
+ + + +V +RP + NS + + +GL+P V ++ +N +C SS E
Sbjct: 1096 STLSSIIVPCYDRPISSRVNSIIEDIARIGLAPNKVKLAYSHPINPFVCWNADSSMEKMK 1155
Query: 801 VYVDLRALRNDRVSLVERGSPHSLCLM-ESGKLLPGVKVITANPETKGQCGDSHLGEIWV 859
Y D LR+ V++ E + L+ SG ++ +PE K C + +GEIW+
Sbjct: 1156 DYFDANQLRSGLVNVREDVLRNRQPLLYGSGTSTLYNEICIVHPEEKYICQEGEIGEIWI 1215
Query: 860 QSPHNASGYFTIYGDESDYADHFSAQLVTGNTGEVYARTGYLGFL 904
H + Y + ++ + + Y+RTG LGF+
Sbjct: 1216 NGKHGS------YCENNELNSGCELLVQETLDKKSYSRTGQLGFI 1254
>UniRef50_Q2RPP1 Cluster: Aspartate racemase; n=1; Rhodospirillum
rubrum ATCC 11170|Rep: Aspartate racemase -
Rhodospirillum rubrum (strain ATCC 11170 / NCIB 8255)
Length = 1981
Score = 86.2 bits (204), Expect = 4e-15
Identities = 108/466 (23%), Positives = 181/466 (38%), Gaps = 30/466 (6%)
Query: 449 ARKYQFISQILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVN 508
A ++ + +L RA S + + L+ G +V + L +A I LL KG
Sbjct: 3 APRWATMGAMLLDRAASLEESCAYRFLHDGGGGPEVRSYRALTSRALDIATFLLAKGCAK 62
Query: 509 TGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVR-MIVDVSKA-TL 566
V ++ P G+ + A +GC GA+ V PP LP +R ++ D + L
Sbjct: 63 RP--VLILLPTGMAFVEALFGCFLAGAIAVPAPPPTGTR---GLPRIRGILADCAPPLAL 117
Query: 567 VLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKKLPIMYRAPTAEMLAYLDFSVST 626
V+ + +L +A L W D P M A +A L ++ +
Sbjct: 118 VVEPPQIDRLGGGDDAP--LARTEWVRVADIPACATPD-PSMVEAVAPGDIAVLQYTSGS 174
Query: 627 TGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSI 686
TG G+ +SH K + L + +G L ++ G
Sbjct: 175 TGTPKGVVISHRNALINLAQQKSGMRAPDGARLVSWLPVHHDMGLFGNILITVAVGGELS 234
Query: 687 LIPPSEVEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTC 746
+ PS P W+ A+S Y+ + + +LC + ++L+ T
Sbjct: 235 FMAPSSFLQKPIRWVQAISDYRGQASGGPDFGFDLCAR----RAQPADLAALDLSSWTTA 290
Query: 747 VVVAEERPRINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPSTVYVDLR 806
AE R F+++F+A G A+ +G I S + T +D+R
Sbjct: 291 YSGAEP-VRAATLERFARVFAASGFRCEALRPCYGLAEATLIV-----SVQAVTQSLDVR 344
Query: 807 ALRNDRVSL---VERGSPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPH 863
R DR SL + R S L G + G+++ + T D+ +GEIW+ P+
Sbjct: 345 --RYDRQSLFAGIARQSDDGEALTSCGPAVEGMEIAIVDAATSQPLPDNRVGEIWLSGPN 402
Query: 864 NASGYFTIYGDESDYADHFSAQLVTGNTGEVYARTGYLGFLRRTEI 909
A GY + A F A+L G+ + R+G +GFL R ++
Sbjct: 403 LAEGY---WNQPQMTAKRFGARL--AGRGDRWLRSGDVGFLDRGQL 443
Score = 50.0 bits (114), Expect = 3e-04
Identities = 52/228 (22%), Positives = 85/228 (37%), Gaps = 11/228 (4%)
Query: 16 EGEHMVCVLDFKRETGLWHAVLASVLNGMHVIFIPYALMKVSPASWMHMITKHRASIAIV 75
+G +V L + GL+ +L +V G + F+ + P W+ I+ +R +
Sbjct: 203 DGARLVSWLPVHHDMGLFGNILITVAVGGELSFMAPSSFLQKPIRWVQAISDYRGQAS-- 260
Query: 76 KSRDLHWGLLATRDHK-EISLSSLRMLLVA-DGANPWSLSSCDQFLSVFQSKGVRGDAIC 133
D + L A R +++ L A GA P ++ ++F VF + G R +A+
Sbjct: 261 GGPDFGFDLCARRAQPADLAALDLSSWTTAYSGAEPVRAATLERFARVFAASGFRCEALR 320
Query: 134 PCACSSESMTVCIXXXXXXXXXXXXXVLSMSGLSYGVVRVDAENSLTSLTLQDCGQVMPS 193
PC +E+ I L G+ R + L CG +
Sbjct: 321 PCYGLAEA--TLIVSVQAVTQSLDVRRYDRQSLFAGIARQSDDGE----ALTSCGPAVEG 374
Query: 194 CVIVVVKMEGPAYLCKTDEVGEICVLSGATGSGYWGLPGLTNTVFRVR 241
I +V L + VGEI + GYW P +T F R
Sbjct: 375 MEIAIVDAATSQPL-PDNRVGEIWLSGPNLAEGYWNQPQMTAKRFGAR 421
>UniRef50_Q4C7P5 Cluster: AMP-dependent synthetase and
ligase:Acyl-CoA dehydrogenase, C- terminal:Acyl-CoA
dehydrogenase, central region:Acyl-CoA dehydrogenase,
N-terminal:Phosphopantetheine-binding; n=1; Crocosphaera
watsonii WH 8501|Rep: AMP-dependent synthetase and
ligase:Acyl-CoA dehydrogenase, C- terminal:Acyl-CoA
dehydrogenase, central region:Acyl-CoA dehydrogenase,
N-terminal:Phosphopantetheine-binding - Crocosphaera
watsonii
Length = 1337
Score = 86.2 bits (204), Expect = 4e-15
Identities = 66/256 (25%), Positives = 114/256 (44%), Gaps = 10/256 (3%)
Query: 455 ISQILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVA 514
+ +L+ RA + + + +T L + L+ + L +A+ I L G+
Sbjct: 8 VVNLLQHRASNHAQKLSYTFLTSGETEEIALSYSNLESQAKTIAAQLQNLNM--QGERAL 65
Query: 515 LIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVI 574
L++P GL+ I AF+GCLY G V V + PP + L + I ++A ++L+ S
Sbjct: 66 LLYPSGLEFIAAFFGCLYAGVVAVPVYPPQGKQ---PLSRLEAIAKNAQAKIILTT-SNY 121
Query: 575 KLLRSKEASNVLDSKAWPMTLDTDDMPKKKLPIMYRAP--TAEMLAYLDFSVSTTGMLAG 632
K + S + SK +T T D L ++ P + LA+L ++ +TG G
Sbjct: 122 KAEIKQYFSQI--SKFDDLTYLTTDNLDSSLGFDWKKPNINSNTLAFLQYTSGSTGNPKG 179
Query: 633 IKMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIPPSE 692
+ +SH + ++ A H + L PY +G + +Y G L+ PS
Sbjct: 180 VMVSHGNLLKNSANIYQAFNHNSDSHGVIWLPPYHDMGLIGGIIQPLYGGFPVTLMSPSS 239
Query: 693 VEVNPALWLSAVSQYK 708
P WL A+S+Y+
Sbjct: 240 FIRKPIRWLKAISRYQ 255
Score = 51.2 bits (117), Expect = 1e-04
Identities = 34/113 (30%), Positives = 54/113 (47%), Gaps = 5/113 (4%)
Query: 797 EPSTVYVDLRALRNDRVSLVERGSPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGE 856
EP + VD + L+ ++V L + + ++ G+ +I +PET C +GE
Sbjct: 387 EPKIIKVDSKELQKNKVVLTSEETIKTQKIVSCGRPAIDENIIIVDPETALPCPPETVGE 446
Query: 857 IWVQSPHNASGYFTIYGDESDYADHFSAQLVTGNTGEVYARTGYLGFLRRTEI 909
IWV A GY + DE F+A L + + + RTG LGFL + E+
Sbjct: 447 IWVSGASIAQGY---WQDEDATEKAFNAYL--PDNKKPFLRTGDLGFLHQGEL 494
Score = 44.4 bits (100), Expect = 0.017
Identities = 47/221 (21%), Positives = 88/221 (39%), Gaps = 11/221 (4%)
Query: 171 VRVDAENSLTSLTLQDCGQVMPSCVIVVVKMEGPAYLCKTDEVGEICVLSGATGSGYWGL 230
V + +E ++ + + CG+ I++V E A C + VGEI V + GYW
Sbjct: 403 VVLTSEETIKTQKIVSCGRPAIDENIIIVDPE-TALPCPPETVGEIWVSGASIAQGYWQD 461
Query: 231 PGLTNTVFRVRPLDSDGEPIGEEHYVRSXXXXXXXXXXXXXXXXSRDGLMTVTGRKHNMD 290
T F P ++ ++R+ +D ++ + GR +
Sbjct: 462 EDATEKAFNAY------LPDNKKPFLRTGDLGFLHQGELFVTGRIKD-IIIIRGRNYYPQ 514
Query: 291 DIIATVLAVEPMKFIYRGRIAVFSVRVLRDERICIVAEQRPDCGEEESFQWMSRVLQA-V 349
DI TV P + S+ E++ I+ E + ++ +FQ + +++ V
Sbjct: 515 DIENTVKNCHPA--LRDHSCVATSITSEEGEKLVIIGEIKRKLEQKINFQEIVNTIRSHV 572
Query: 350 DSIHQVGIYCLALVQPNFLPKTPLGGIHLSECKRRFLEGTL 390
H + + LV+ +PKT G I K+ +LE +
Sbjct: 573 SRKHGIQTNKIVLVKQGSIPKTSSGKIQRLAGKKAYLENNI 613
Score = 40.7 bits (91), Expect = 0.21
Identities = 15/36 (41%), Positives = 24/36 (66%)
Query: 952 VFVVGALDETIMLRGMRYHPIDIENSVMRCHKKIAE 987
+FV G + + I++RG Y+P DIEN+V CH + +
Sbjct: 494 LFVTGRIKDIIIIRGRNYYPQDIENTVKNCHPALRD 529
>UniRef50_A5NY43 Cluster: AMP-dependent synthetase and ligase; n=1;
Methylobacterium sp. 4-46|Rep: AMP-dependent synthetase
and ligase - Methylobacterium sp. 4-46
Length = 555
Score = 86.2 bits (204), Expect = 4e-15
Identities = 111/454 (24%), Positives = 175/454 (38%), Gaps = 42/454 (9%)
Query: 457 QILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVALI 516
++ RW A+ D + F + V+ LT L + A + L E G G V L+
Sbjct: 7 RLARWSAERP-DRLAFAFMPDGTTVTDALTFGALDRDARGVARSLGEVGA--GGRPVLLL 63
Query: 517 FPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKL 576
PG + A GCLY GA L T +P R V++ V + +
Sbjct: 64 CEPGPAFVTALVGCLYAGA------------LATPVPVSRRRAGVARLAAVARDADPAAI 111
Query: 577 LRSKEASNVLDSKAWPMTLDTDDMPKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMS 636
L + + S V D + D + P A + A + ++ +T G+ +S
Sbjct: 112 LATVDRSAVPDERLAAAPWLRVDEAARNAPAAVSAVAEDHPAVIQYTSGSTTSPKGVVLS 171
Query: 637 HAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIPPSEVEVN 696
H + + R ++ + S L + +G L+++Y+G PP
Sbjct: 172 HGNLAANLRMLRDGFGAHESSRYLSWLPLFHDMGLIAHVLAALYNGGPCWFAPPLSFFRR 231
Query: 697 PALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVVAEERPRI 756
P WL A++ + + E C + + ++ G++LA AE R
Sbjct: 232 PETWLRAIALHGATISGAPNFAYESCVRRFPT----MQLDGLSLASWEVAFCGAEA-VRA 286
Query: 757 NLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPSTVYVDLRALRNDRVSLV 816
+ FS LF+ G A+ +G +TV+V A R R +L
Sbjct: 287 STMERFSALFAPYGFRAAALRPCYGLA--------------EATVFVT--AARGVR-TLP 329
Query: 817 ERGSPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNASGYFTIYGDES 876
SP + L+ G P ++ +PET D +GEI V H A Y+ ES
Sbjct: 330 ATQSPTAAPLVSCGTPSPDATLVVVDPETLRPRQDGEIGEICVSGSHVAKAYWR-RPAES 388
Query: 877 DYADHFSAQLVTGNTGEVYA-RTGYLGFLRRTEI 909
D F A+ + G G V A RTG LG LR E+
Sbjct: 389 DAT--FGAE-IEGPDGPVTALRTGDLGLLRDGEL 419
Score = 68.1 bits (159), Expect = 1e-09
Identities = 93/393 (23%), Positives = 152/393 (38%), Gaps = 34/393 (8%)
Query: 1 MLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLASVLNGMHVIFIPYALMKVSPAS 60
+ A+ RML E + L + GL VLA++ NG F P P +
Sbjct: 175 LAANLRMLRDGFGAHESSRYLSWLPLFHDMGLIAHVLAALYNGGPCWFAPPLSFFRRPET 234
Query: 61 WMHMITKHRASIAIVKSRDLHWGL--LATRDHKEISLSSLRMLLVADGANPWSLSSCDQF 118
W+ I H A+I+ + + T +SL+S + GA S+ ++F
Sbjct: 235 WLRAIALHGATISGAPNFAYESCVRRFPTMQLDGLSLASWEVAFC--GAEAVRASTMERF 292
Query: 119 LSVFQSKGVRGDAICPCACSSESMTVCIXXXXXXXXXXXXXVLSMSGLSYGVVRVDAENS 178
++F G R A+ PC +E+ TV + GV + A S
Sbjct: 293 SALFAPYGFRAAALRPCYGLAEA-TVFVTAAR------------------GVRTLPATQS 333
Query: 179 LTSLTLQDCGQVMPSCVIVVVKMEGPAYLCKTDEVGEICVLSGATGSGYWGLPGLTNTVF 238
T+ L CG P +VVV E + E+GEICV YW P ++ F
Sbjct: 334 PTAAPLVSCGTPSPDATLVVVDPE-TLRPRQDGEIGEICVSGSHVAKAYWRRPAESDATF 392
Query: 239 RVRPLDSDGEPIGEEHYVRSXXXXXXXXXXXXXXXXSRDGLMTVTGRKHNMDDIIATVLA 298
+ +G P G +R+ +D ++ V G + +D+ V A
Sbjct: 393 GA---EIEG-PDGPVTALRTGDLGLLRDGELYVTGRLKD-VILVRGETIHAEDVEQAVGA 447
Query: 299 VEPMKFIYRGRIAVFSVRVLRDERICIVAEQRPDCGEEESFQWM-SRVLQAVDSIHQVGI 357
P G A F + V +E++ +V ++ P G + + + +AV V +
Sbjct: 448 SHPE---LDGLCAAFGLEVDGEEQV-VVVQEAPRGGFRAAPETLIDAAARAVADTFGVRL 503
Query: 358 YCLALVQPNFLPKTPLGGIHLSECKRRFLEGTL 390
Y LA V+ +P+T G + C+ + G L
Sbjct: 504 YDLARVRTGAIPRTTSGKVQRGRCRALYASGEL 536
>UniRef50_Q2Y7Z2 Cluster: Amino acid adenylation; n=1; Nitrosospira
multiformis ATCC 25196|Rep: Amino acid adenylation -
Nitrosospira multiformis (strain ATCC 25196 / NCIMB
11849)
Length = 1801
Score = 85.4 bits (202), Expect = 7e-15
Identities = 89/428 (20%), Positives = 162/428 (37%), Gaps = 25/428 (5%)
Query: 478 KGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVP 537
+GAV K L + + +L + R + G+ L+ + F+ CLY G +
Sbjct: 40 EGAVEKAFDYRTLDQHVRALAAILQD--RFSAGERALLLMENDEHYVIGFFACLYAGLIA 97
Query: 538 VTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDT 597
V + PP + + D ++A +L+ ++ L+ A ++ ++ + L
Sbjct: 98 VPVFPPEMVRERHLARLLAIAAD-AEARCILTTSEIMPLI----ARAAVEQFSYAIVLTV 152
Query: 598 DDMPKKKLPIMYRAPTAEM-LAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPS 656
D + AE +A+L ++ +T G+ +SH ++ + R + + +
Sbjct: 153 DTVKCDNASAWRECSPAEGDIAFLQYTSGSTSTPKGVMVSHGSLMTNTRVFEEGMSINAN 212
Query: 657 RHIALCLDPYCGLGFALWCLSSIYSGHHSILIPPSEVEVNPALWLSAVSQYKVRDTFCSY 716
L Y +G L I+ G +L+ P P WL A+S Y+ +
Sbjct: 213 DIFVSWLPLYHDMGLIGGLLQPIHRGIPVVLMTPRFFIERPVRWLKAISHYRATVSGAPN 272
Query: 717 GVMELCTKGLGSSVNQLKSKGINLACVRTCVVVAEERPRINLTNSFSKLFSALGLSPRAV 776
+LC V+ + + ++L+ R AE R + +F + F+ G P +
Sbjct: 273 FAFQLC----ADRVSDAQLQELDLSSWRVAFSGAEPVRRETM-KAFIERFAPAGFPPGTI 327
Query: 777 STSFGCRVNIAICLQGASSPEPSTVYVDLRALRNDRVSLVERGSPHSLCLMESGKLLPGV 836
+G G + L +V + E+G+ L+ G G
Sbjct: 328 YPCYGLAEATLFVTGGTRGDGMEAHCFSTQLLAQGKVEVAEQGT----SLVACGVPASGH 383
Query: 837 KVITANPETKGQCGDSHLGEIWVQSPHNASGYFTIYGDESDYADHFSAQLVTGNTGEVYA 896
V +PET Q D +GEIW A GY+ +A+ G +
Sbjct: 384 TVRVVDPETGVQLPDGTIGEIWTDGASLACGYWR--------KPEETAETFVSREGGRWL 435
Query: 897 RTGYLGFL 904
RTG LGF+
Sbjct: 436 RTGDLGFI 443
Score = 51.2 bits (117), Expect = 1e-04
Identities = 85/395 (21%), Positives = 148/395 (37%), Gaps = 28/395 (7%)
Query: 1 MLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLASVLNGMHVIFIPYALMKVSPAS 60
++ + R+ + + V L + GL +L + G+ V+ + P
Sbjct: 196 LMTNTRVFEEGMSINANDIFVSWLPLYHDMGLIGGLLQPIHRGIPVVLMTPRFFIERPVR 255
Query: 61 WMHMITKHRASIAIVKSRDLHWGLLATR----DHKEISLSSLRMLLVADGANPWSLSSCD 116
W+ I+ +RA+++ + + + L A R +E+ LSS R+ GA P +
Sbjct: 256 WLKAISHYRATVS--GAPNFAFQLCADRVSDAQLQELDLSSWRVAF--SGAEPVRRETMK 311
Query: 117 QFLSVFQSKGVRGDAICPCACSSESMTVCIXXXXXXXXXXXXXVLSMSGLSYGVVRVDAE 176
F+ F G I PC +E+ S L+ G V V AE
Sbjct: 312 AFIERFAPAGFPPGTIYPCYGLAEA--TLFVTGGTRGDGMEAHCFSTQLLAQGKVEV-AE 368
Query: 177 NSLTSLTLQDCGQVMPSCVIVVVKMEGPAYLCKTDEVGEICVLSGATGSGYWGLPGLTNT 236
TSL CG + VV E L +GEI + GYW P T
Sbjct: 369 QG-TSLVA--CGVPASGHTVRVVDPETGVQL-PDGTIGEIWTDGASLACGYWRKPEETAE 424
Query: 237 VFRVRPLDSDGEPIGEEHYVRSXXXXXXXXXXXXXXXXSRDGLMTVTGRKHNMDDIIATV 296
F + +G ++R+ +D L+ + G+ D+ +
Sbjct: 425 TF----VSREG-----GRWLRTGDLGFIHDGQLYIAGRRKD-LIIIRGQNVYPQDLEQVI 474
Query: 297 LAVEPMKFIYRGRIAVFSVRVLRDERICIVAEQRPDCGEEESFQWMSRVL-QAVDSIHQV 355
+ ++ +GR+A FSV E I + E + + + + + L +AV
Sbjct: 475 --EDEVEAARKGRVAAFSVETENGEGIGMAVEISRGMQKLIAVETLVQALSEAVSGSCHE 532
Query: 356 GIYCLALVQPNFLPKTPLGGIHLSECKRRFLEGTL 390
+ + L+ P LPKT G + + C++ + E TL
Sbjct: 533 PLSVVVLLNPGGLPKTSSGKLQRAACRQGWRERTL 567
>UniRef50_Q10976 Cluster: Putative fatty-acid--CoA ligase fadD26;
n=96; Mycobacterium|Rep: Putative fatty-acid--CoA ligase
fadD26 - Mycobacterium tuberculosis
Length = 583
Score = 85.4 bits (202), Expect = 7e-15
Identities = 112/470 (23%), Positives = 186/470 (39%), Gaps = 35/470 (7%)
Query: 455 ISQILRWRAQSTSDHVIFTLLN----AKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTG 510
+ +L+ RA D +T ++ KG LT ++++ +A I L G G
Sbjct: 8 VPSLLQERADQQPDSTAYTYIDYGSDPKGFADS-LTWSQVYSRACIIAEELKLCGL--PG 64
Query: 511 DHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSN 570
D VA++ P GL+ + AF G L G + V + P +H V ++ SK +L+
Sbjct: 65 DRVAVLAPQGLEYVLAFLGALQAGFIAVPLSTPQ-YGIHD--DRVSAVLQDSKPVAILTT 121
Query: 571 QSVIKLLRSKEASNVLDSKAWPMTLDTD----DMPKKKLPIMYRAPTAEMLAYLDFSVST 626
SV+ + AS+ D + P+ ++ D D P +++P R T AYL ++ +
Sbjct: 122 SSVVGDVTKYAASH--DGQPAPVVVEVDLLDLDSP-RQMPAFSRQHTG--AAYLQYTSGS 176
Query: 627 TGMLAGIKMSHA-AVTSLCRSMKIAC---ELYPSRHIALCLDPYCGLGFALWCLSSIYSG 682
T AG+ +SH + ++ +SM P+ + L Y +G L + + +
Sbjct: 177 TRTPAGVIVSHTNVIANVTQSMYGYFGDPAKIPTGTVVSWLPLYHDMGLILGICAPLVAR 236
Query: 683 HHSILIPPSEVEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLAC 742
++L+ P PA W+ ++ + EL + + G++L
Sbjct: 237 RRAMLMSPMSFLRRPARWMQLLATSGRCFSAAPNFAFELAVR----RTSDQDMAGLDLRD 292
Query: 743 VRTCVVVAEERPRINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPSTVY 802
V +V ER + F + F+ LSP A+ S+G + P TV
Sbjct: 293 V-VGIVSGSERIHVATVRRFIERFAPYNLSPTAIRPSYGLAEATLYVAAPEAGAAPKTVR 351
Query: 803 VDLRALRNDRVSLVERGSPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSP 862
D L + L+ G P V NPET + +GEIWV
Sbjct: 352 FDYEQLTAGQARPCGTDGSVGTELISYGSPDPS-SVRIVNPETMVENPPGVVGEIWVHGD 410
Query: 863 HNASGYFTIYGDESDYADHFSAQLVTGNTGE---VYARTGYLGFLRRTEI 909
H GY + A F A+LV + RTG LG + E+
Sbjct: 411 HVTMGY---WQKPKQTAQVFDAKLVDPAPAAPEGPWLRTGDLGVISDGEL 457
Score = 52.4 bits (120), Expect = 6e-05
Identities = 77/336 (22%), Positives = 121/336 (36%), Gaps = 23/336 (6%)
Query: 58 PASWMHMITKHRASIAIVKSRDLHWGLLATRDHKEISLSSLRMLLVADGANPWSLSSCDQ 117
PA WM ++ + + + T D L ++ + G+ +++ +
Sbjct: 251 PARWMQLLATSGRCFSAAPNFAFELAVRRTSDQDMAGLDLRDVVGIVSGSERIHVATVRR 310
Query: 118 FLSVFQSKGVRGDAICPCACSSESMTVCIXXXXXXXXXXXXXVLSMSGLSYGVVRVDAEN 177
F+ F + AI P +E+ T+ + L+ G R +
Sbjct: 311 FIERFAPYNLSPTAIRPSYGLAEA-TLYVAAPEAGAAPKTVR-FDYEQLTAGQARPCGTD 368
Query: 178 SLTSLTLQDCGQVMPSCVIVV---VKMEGPAYLCKTDEVGEICVLSGATGSGYWGLPGLT 234
L G PS V +V +E P + VGEI V GYW P T
Sbjct: 369 GSVGTELISYGSPDPSSVRIVNPETMVENPPGV-----VGEIWVHGDHVTMGYWQKPKQT 423
Query: 235 NTVFRVRPLDSDGEPIGEEHYVRSXXXXXXXXXXXXXXXXSRDGLMTVTGRKHNMDDIIA 294
VF + +D E ++R+ +D L+ V GR H DDI A
Sbjct: 424 AQVFDAKLVDP-APAAPEGPWLRTGDLGVISDGELFIMGRIKD-LLIVDGRNHYPDDIEA 481
Query: 295 TVLAVEPMKFIYRGRIAVFSVRVLRDERICIVAE--QRPDCGEEESFQWMS---RVLQAV 349
T+ + I GR A +V E++ + E +R EE + S V A+
Sbjct: 482 TI------QEITGGRAAAIAVPDDITEQLVAIIEFKRRGSTAEEVMLKLRSVKREVTSAI 535
Query: 350 DSIHQVGIYCLALVQPNFLPKTPLGGIHLSECKRRF 385
H + + L LV P +P T G I S C R+
Sbjct: 536 SKSHSLRVADLVLVSPGSIPITTSGKIRRSACVERY 571
>UniRef50_Q1ITR1 Cluster: AMP-dependent synthetase and ligase; n=1;
Acidobacteria bacterium Ellin345|Rep: AMP-dependent
synthetase and ligase - Acidobacteria bacterium (strain
Ellin345)
Length = 561
Score = 83.8 bits (198), Expect = 2e-14
Identities = 108/438 (24%), Positives = 183/438 (41%), Gaps = 44/438 (10%)
Query: 483 KVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRP 542
+ +T AE +A R L L + V GD V ++ P +D + F G + +GAVP +
Sbjct: 32 ETVTFAEFRVRA-RAQALALRRAAVGGGDRVVILMPQTIDAMAVFAGAMMIGAVPAFLAY 90
Query: 543 PH----PQNLHTTLPTVRMIVDVSKATLVLSN---QSVIKLLRSKEASNVLDSKAWPMTL 595
P+ P L V ++S +VL + ++ + E S V+ + A
Sbjct: 91 PNFKVEPAKYRAGLAGVT--ANLSAKVIVLDRKFPEDMLGHVSIGEGSRVIRASA----- 143
Query: 596 DTDDMPKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYP 655
++ +L + P +A++ S TTG+ G+ ++HAAV + + A + P
Sbjct: 144 ---EIEGGELELSPLGPNE--IAFIQHSAGTTGLQKGVALTHAAVLRQLQHLADALRIDP 198
Query: 656 -SRHIALCLDPYCGLGFALWCLSSIYSGHHSILIPPS-EVEVNPALWLSAVSQYKVRDTF 713
S I L Y +G + C H +++ S + + P L A++ K
Sbjct: 199 QSDSIYSWLPLYHDMGL-IACFMLPMVCHIPVVMQSSLDWVMQPESLLQAITTCK----- 252
Query: 714 CSYGVM-ELCTKGLGSSVNQLKSKGINLACVRTCVVVAEERPRINLTNSFSKLFSALGLS 772
C+ G M + + V Q + +L+ +R + +E +L F F+A+GL
Sbjct: 253 CTLGWMPNFAFQFVPRRVPQKRWADYDLSSLRALINCSEPVHASSL-REFESAFAAIGLK 311
Query: 773 PRAVSTSFGCRVNIAICLQGASSPEPSTVYVDLRALRNDRV-SLVERGSPHSLCLMESGK 831
+ +S+ N+ Q EP+ V+ D R + V +VE P ++ SG
Sbjct: 312 KGVLQSSYAMAENVFAITQSKIGREPTEVWADGTRFRREHVIEVVESSVPGAVSFASSGS 371
Query: 832 LLPGVKVITANPETKGQCGDSHLGEIWVQSPHNASGYFTIYGDESDYADHFSAQLVTGNT 891
LLP +V N + +GEI ++S +GYF + D SA V G
Sbjct: 372 LLPCNEVQIVN-DAGEPLAPERVGEILIRSDSLFTGYF-------NRPDLTSAAFVNG-- 421
Query: 892 GEVYARTGYLGFLRRTEI 909
+ RTG LGF E+
Sbjct: 422 ---WYRTGDLGFPLNDEL 436
>UniRef50_Q62B68 Cluster: AMP-binding domain protein; n=11;
Burkholderia|Rep: AMP-binding domain protein -
Burkholderia mallei (Pseudomonas mallei)
Length = 621
Score = 83.0 bits (196), Expect = 4e-14
Identities = 65/270 (24%), Positives = 115/270 (42%), Gaps = 5/270 (1%)
Query: 456 SQILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVAL 515
+ +LR+RA++T D + L +V+ ++H++A I ++ GR D V L
Sbjct: 27 ADVLRYRAETTPDEFAYGYLGFGRMPDRVMRYGDIHRRALGIAREIVAHGR--PADPVLL 84
Query: 516 IFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIK 575
IFP D + AF+GCLY G + V PP + L + + D + + + N +
Sbjct: 85 IFPSAADFVEAFFGCLYAGRMAVPALPPRTEKERRRL--ISIARDCAPSFAICGNGEMDA 142
Query: 576 LLRSKEASNVLDSKAWPMTLDTDDMPKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKM 635
+L A+ V+ + D P A +A+L ++ +T G+ +
Sbjct: 143 VLAELCAAGVVAPPCREVGAIADGGDAGDAPGALPAIAPGSIAFLQYTSGSTSDPKGVMV 202
Query: 636 SHAAVTSLCRSMKIACELYPSRHIALC-LDPYCGLGFALWCLSSIYSGHHSILIPPSEVE 694
H + + R ++ R + + L Y +G L IY+G ++ + P +
Sbjct: 203 GHDNLLANERLLRRHWGSDRERWLIVSWLPHYHDMGLIGGILQPIYAGRPAVFMSPQDFL 262
Query: 695 VNPALWLSAVSQYKVRDTFCSYGVMELCTK 724
+PA WL AVS Y + ELC +
Sbjct: 263 QHPARWLHAVSDYGATCSGAPNFGYELCRR 292
>UniRef50_Q5VNP6 Cluster: Acyl-CoA ligase-like; n=4; Oryza
sativa|Rep: Acyl-CoA ligase-like - Oryza sativa subsp.
japonica (Rice)
Length = 622
Score = 82.2 bits (194), Expect = 7e-14
Identities = 105/439 (23%), Positives = 176/439 (40%), Gaps = 39/439 (8%)
Query: 483 KVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRP 542
+ LT +EL +R+ LLE R GD V ++ PG+ L+ + C G V V + P
Sbjct: 52 ETLTYSELDSAVQRMAAGLLEVLR--RGDTVLVLASPGIRLVKLMFACQRAGLVAVPVIP 109
Query: 543 PHPQNLHTTL--PTVRMI---VDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDT 597
P P + T P R + V ++ +++ + + ++ + + L S W
Sbjct: 110 PDPSVIGTPAEGPAHRHLLRAVSQARPRAAVADAGYVGAV-TRSSISALMSLNWVSVDRL 168
Query: 598 DDMPKKKLPI------MYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIAC 651
+ P + +Y + ++ TG + ++ A R+ + A
Sbjct: 169 ERWPAVASTVAATGDGVYEGCGPRETYLVQYTSGATGDPKPVVVTAGAAAHNARAARKAY 228
Query: 652 ELYPSRHIALCLDPY--CGLGFALWCLSSIYSGHHSILIPPSEVEVNPALWLSAVSQYKV 709
+L P + L Y CGL F L ++ SG +L S P LWL +S++K
Sbjct: 229 DLRPGSVVVSWLPQYHDCGLMFLLL---TVVSGATCVLTSASAFVRRPRLWLELISEFKA 285
Query: 710 RDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVVAEERPRINLTNSFSKLFSAL 769
T + L + G S + ++ + L +R ++V E + + + F + F
Sbjct: 286 TCTPVPSFALPLVLRR-GRSEHG--TRPLQLQTLRNLILVNEPIYK-SPVDEFLEEFGPA 341
Query: 770 GLSPRAVSTSFGCRVNIAICLQGASSPEPSTVYVDLRALRNDRVSLVERGSPHSLCLMES 829
GL ++S S+G N E + L + + L P L E+
Sbjct: 342 GLRASSISPSYGLAENCTFVSTAWRGTEVT--------LPSYKKLLPSARLPQPSLLTEA 393
Query: 830 GKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNASGYFTIYGDESDYADHFSAQLVTG 889
P V+++ + ET D GEIW+ SP N SGY GD + F A+L G
Sbjct: 394 ----PDVEIVVVDAETGKLVEDGVEGEIWLSSPSNGSGYL---GDSPASREVFGARL-QG 445
Query: 890 NTGEVYARTGYLGFLRRTE 908
G + RT LG + TE
Sbjct: 446 RAGPCFVRTSDLGVVHGTE 464
Score = 42.3 bits (95), Expect = 0.068
Identities = 88/392 (22%), Positives = 145/392 (36%), Gaps = 28/392 (7%)
Query: 4 HCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLASVLNGMHVIFIPYALMKVSPASWMH 63
+ R A + G +V L + GL +L +V++G + + P W+
Sbjct: 220 NARAARKAYDLRPGSVVVSWLPQYHDCGLMFLLL-TVVSGATCVLTSASAFVRRPRLWLE 278
Query: 64 MITKHRASIAIVKSRDLHWGLLATR-DH--KEISLSSLRMLLVADGANPWSLSSCDQFLS 120
+I++ +A+ V S L L R +H + + L +LR L++ + P S D+FL
Sbjct: 279 LISEFKATCTPVPSFALPLVLRRGRSEHGTRPLQLQTLRNLILVN--EPIYKSPVDEFLE 336
Query: 121 VFQSKGVRGDAICPCACSSESMTVCIXXXXXXXXXXXXXVLSMSGLSYGVVRVDAENSLT 180
F G+R +I P +E+ T ++ SY + A
Sbjct: 337 EFGPAGLRASSISPSYGLAENCTFVSTAWRGT---------EVTLPSYKKLLPSARLPQP 387
Query: 181 SLTLQDCGQVMPSCVIVVVKMEGPAYLCKTDEVGEICVLSGATGSGYWGLPGLTNTVFRV 240
SL + P IVVV E L + GEI + S + GSGY G + VF
Sbjct: 388 SLLTE-----APDVEIVVVDAE-TGKLVEDGVEGEIWLSSPSNGSGYLGDSPASREVFGA 441
Query: 241 RPLDSDGEPIGEEHYVRSXXXXXXXXXXXXXXXXSR--DGLMTVTGRKHNMDDIIATVLA 298
R L P +VR+ R D ++ ++ I T
Sbjct: 442 R-LQGRAGPC----FVRTSDLGVVHGTERYLYVLGRTTDAIVVADSQRRVPAHYIETAAF 496
Query: 299 VEPMKFIYRGRIAVFSVRVLRDERICIVAEQRPDCGEEESFQWMSRVLQAVDSIHQVGIY 358
+ G IA F+ + + +VAE + G + + QAV V +
Sbjct: 497 ESSPGRLRGGCIASFTTLPVSPSPVVVVAELQNGGGGGDMAGICHGIRQAVWREVGVTVA 556
Query: 359 CLALVQPNFLPKTPLGGIHLSECKRRFLEGTL 390
+ L + +PKT G + + + L G L
Sbjct: 557 RVVLAESGGVPKTTSGKLQRGAARAKLLAGKL 588
>UniRef50_A7HI15 Cluster: AMP-dependent synthetase and ligase; n=4;
Cystobacterineae|Rep: AMP-dependent synthetase and
ligase - Anaeromyxobacter sp. Fw109-5
Length = 586
Score = 81.0 bits (191), Expect = 2e-13
Identities = 101/396 (25%), Positives = 163/396 (41%), Gaps = 27/396 (6%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPP- 543
L E+ +AER L +G V G+ VA++ G + + AF+G GAVPV + PP
Sbjct: 42 LPWGEVVARAERTAAALAARG-VAPGERVAIVLRTGPEFLDAFFGTWLAGAVPVPLYPPV 100
Query: 544 HPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPM--TLDTDDMP 601
+ L ++ VS A LV+S+ +V +LL A +A P +D ++
Sbjct: 101 RLGRMEEYLAQTARMLAVSGARLVVSSGAVRRLLGGAVA------RAAPALGCVDVAELA 154
Query: 602 KKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIAL 661
+ + R P E L + FS +T + +SHAA+ + ++ A +
Sbjct: 155 EGG-ERLARMPAPEDLGLVQFSSGSTVDPKAVALSHAALQAQADALMAAVRPDARDALVS 213
Query: 662 CLDPYCGLGFALWCLSSIYSGHHSILIPPSEVEVNPALWLSAVSQYKVRDTFCSYGVMEL 721
L Y +G L+++ +LIPP PALWL A+++++ +
Sbjct: 214 WLPLYHDMGLIGCLLAAMSYPGPLVLIPPEHFLARPALWLRAIARHRGTISVAPSFAYAF 273
Query: 722 CTKGLGSSVNQLKSKGINLACVRTCVVVAEERPRINLTNSFSKLFSALGLSPRAVSTSFG 781
C + V + G +LA R + AE + F F G P AV +G
Sbjct: 274 CAE----RVADAELAGSSLASWRLALNGAEP-VSADALRRFLARFVPYGFDPGAVVPVYG 328
Query: 782 -CRVNIAICLQGASSPEPSTVYVDLRALRNDRVSLVERGSPHSLCLMESGKLLPGVKVIT 840
+A+ P +T LR R+ V+ R L+ G + GV+V
Sbjct: 329 LSEAALAVTWSPHGRPLATTRLDPLRLARDGVVATGTRE------LVSVGVPIAGVEV-E 381
Query: 841 ANPETKGQCGDSHLGEIWVQSPHNASGYFTIYGDES 876
E G+ LG ++V+ P GY GDE+
Sbjct: 382 LRDEGGAPAGEGRLGRVFVRGPSLMRGYL---GDEA 414
Score = 40.3 bits (90), Expect = 0.27
Identities = 31/122 (25%), Positives = 51/122 (41%)
Query: 20 MVCVLDFKRETGLWHAVLASVLNGMHVIFIPYALMKVSPASWMHMITKHRASIAIVKSRD 79
+V L + GL +LA++ ++ IP PA W+ I +HR +I++ S
Sbjct: 211 LVSWLPLYHDMGLIGCLLAAMSYPGPLVLIPPEHFLARPALWLRAIARHRGTISVAPSFA 270
Query: 80 LHWGLLATRDHKEISLSSLRMLLVADGANPWSLSSCDQFLSVFQSKGVRGDAICPCACSS 139
+ D + S L +GA P S + +FL+ F G A+ P S
Sbjct: 271 YAFCAERVADAELAGSSLASWRLALNGAEPVSADALRRFLARFVPYGFDPGAVVPVYGLS 330
Query: 140 ES 141
E+
Sbjct: 331 EA 332
>UniRef50_A4KE92 Cluster: Fatty-acid-CoA ligase fadD30; n=6;
Mycobacterium tuberculosis complex|Rep: Fatty-acid-CoA
ligase fadD30 - Mycobacterium tuberculosis str. Haarlem
Length = 585
Score = 81.0 bits (191), Expect = 2e-13
Identities = 103/462 (22%), Positives = 187/462 (40%), Gaps = 30/462 (6%)
Query: 459 LRWRAQSTSDHVIFTLLN---AKGAVSKVLTCAELHKKAERIGNLLLEKGR-VNTGDHVA 514
LR RA +T F ++ G +T ++L+ + + L+ GR + A
Sbjct: 7 LRDRATTTPSDEAFVFMDYDTKTGDQIDRMTWSQLYSRVTAVSAYLISYGRHADRRRTAA 66
Query: 515 LIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVI 574
+ P GLD + F G L G PV + P P T ++D + A +VL+
Sbjct: 67 ISAPQGLDYVAGFLGALCAGWTPVPL--PEPLGSLRDKRTGLAVLDCA-ADVVLTTSQAE 123
Query: 575 KLLRSKEASNVLDSKAWPMTLDTDDMPKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIK 634
+R+ A++ + LDT D P + ++ +YL ++ +T G+
Sbjct: 124 TRVRATIATHGASVTTPVIALDTLDEPSGD-NCDLDSQLSDWSSYLQYTSGSTANPRGVV 182
Query: 635 MSHAAVT----SLCRSM---KIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSIL 687
+S VT + R+ + PS + L Y +G + ++ G IL
Sbjct: 183 LSMRNVTENVDQIIRNYFRHEGGAPRLPS-SVVSWLPLYHDMGLMVGLFIPLFVGCPVIL 241
Query: 688 IPPSEVEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCV 747
P PA W+ +++++ + +L + ++ G++L V T +
Sbjct: 242 TSPEAFIRKPARWMQLLAKHQAPFSAAPNFAFDLAV----AKTSEEDMAGLDLGHVNT-I 296
Query: 748 VVAEERPRINLTNSFSKLFSALGLSPRAVSTSFG-CRVNIAICLQGASSPEPSTVY-VDL 805
+ E+ + N F + F L P AV S+G + + A SP ST + D
Sbjct: 297 INGAEQVQPNTITKFLRRFRPYNLMPAAVKPSYGMAEAVVYLATTKAGSPPTSTEFDADS 356
Query: 806 RALRNDRVSLVERGSPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNA 865
A + +S E L S P ++++ +P++ + G +GEIW+ + +
Sbjct: 357 LARGHAELSTFETERATRLIRYHSDDKEPLLRIV--DPDSNIELGPGRIGEIWIHGKNVS 414
Query: 866 SGYFTIYGDESDYADHFSAQLVTGNTG---EVYARTGYLGFL 904
+GY D++ D F A + + G + RTG LGF+
Sbjct: 415 TGYHN--ADDALNRDKFQASIREASAGTPRSPWLRTGDLGFI 454
Score = 48.8 bits (111), Expect = 8e-04
Identities = 79/374 (21%), Positives = 135/374 (36%), Gaps = 21/374 (5%)
Query: 20 MVCVLDFKRETGLWHAVLASVLNGMHVIFI-PYALMKVSPASWMHMITKHRASIAIVKSR 78
+V L + GL + + G VI P A ++ PA WM ++ KH+A + +
Sbjct: 213 VVSWLPLYHDMGLMVGLFIPLFVGCPVILTSPEAFIR-KPARWMQLLAKHQAPFSAAPNF 271
Query: 79 DLHWGLLATRDHKEISLSSLRMLLVADGANPWSLSSCDQFLSVFQSKGVRGDAICPCACS 138
+ T + L + + +GA ++ +FL F+ + A+ P
Sbjct: 272 AFDLAVAKTSEEDMAGLDLGHVNTIINGAEQVQPNTITKFLRRFRPYNLMPAAVKPSYGM 331
Query: 139 SESMTVCIXXXXXXXXXXXXXVLSMSGLSYGVVRVDAENSLTSLTLQDCGQVMPSCVIVV 198
+E++ + + T L P ++ +
Sbjct: 332 AEAVVYLATTKAGSPPTSTEFDADSLARGHAELSTFETERATRLIRYHSDDKEP--LLRI 389
Query: 199 VKMEGPAYLCKTDEVGEICVLSGATGSGYWGLP-GLTNTVFRVRPLD-SDGEPIGEEHYV 256
V + L +GEI + +GY L F+ + S G P ++
Sbjct: 390 VDPDSNIEL-GPGRIGEIWIHGKNVSTGYHNADDALNRDKFQASIREASAGTP--RSPWL 446
Query: 257 RSXXXXXXXXXXXXXXXXSRDGLMTVTGRKHNMDDIIATVLAVEPMKFIYRGRIAVFSVR 316
R+ +D L+ G H DDI TV K GR+A FSV
Sbjct: 447 RTGDLGFIVGDEFYIVGRMKD-LIIQDGVNHYPDDIETTV------KEFTGGRVAAFSVS 499
Query: 317 VLRDERICIVAEQRPDCGEEE----SFQWMSR-VLQAVDSIHQVGIYCLALVQPNFLPKT 371
E + I AE R + G ++ F + R V+ A+ +H + + LV P LPKT
Sbjct: 500 DDGVEHLVIAAEVRTEHGPDKVTIMDFSTIKRLVVSALSKLHGLHVTDFLLVPPGALPKT 559
Query: 372 PLGGIHLSECKRRF 385
G I + C +++
Sbjct: 560 TSGKISRAACAKQY 573
>UniRef50_Q82U49 Cluster: AMP-dependent synthetase and ligase; n=3;
Nitrosomonadaceae|Rep: AMP-dependent synthetase and
ligase - Nitrosomonas europaea
Length = 610
Score = 80.2 bits (189), Expect = 3e-13
Identities = 102/444 (22%), Positives = 190/444 (42%), Gaps = 19/444 (4%)
Query: 472 FTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCL 531
+ +++G + VL +L ++ I L G VALI + I F+ C
Sbjct: 59 YNFYDSRGNLKSVLAYKDLCANSKIIARRLSGLGLARNS-RVALIADTTPEFIELFFACR 117
Query: 532 YVGAVPVTIRPPHPQNLHTT---LPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDS 588
+ G VP + P P NL + + +R +++ SKA++ ++N ++ L S V
Sbjct: 118 FAGLVPFAM--PVPVNLGSRAIYVQQLRGMLESSKASVAVANLDFVEFLNEAVGSLVSSE 175
Query: 589 KAWPMTLDTDDMPKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMK 648
W T + D+ + +++ T + AYL F+ +T + G+ ++ A+ + R +
Sbjct: 176 LKWSGTPEQLDL-LPEADVVFSPNTPDETAYLQFTSGSTRLPRGVVITERALMTNLRGIV 234
Query: 649 I-ACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIPPSEVEVNPALWLSAVSQY 707
++ A L Y +G L+ + + + + V P WL +S+
Sbjct: 235 CNGLDVRLGDRCASWLPFYHDMGLVGLVLAPLAAQLSVDYLATRDFAVRPLQWLKLISRN 294
Query: 708 KVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVVAEERPRINLTNSFSKLFS 767
+ F ++LCT L + + L ++L+C R V A E R++ SF+ F+
Sbjct: 295 RCTIAFSQPFGLKLCT--LRARESDLAD--LDLSCWRAAGVGA-EMIRMDTLKSFAAKFA 349
Query: 768 ALGLSPRAVSTSFG-CRVNIAICLQGASSPEPSTVYVDLRALRNDRVSL-VERGSPHSLC 825
A G RA +G +A+ S S + VD R L ++++ V+
Sbjct: 350 AAGFDERAFLPCYGLAESTLAVSFPDISRGARS-LRVDARTLIEKKIAVRVQAEGRKYNE 408
Query: 826 LMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNASGYFTIYGDESDYADHFSAQ 885
+ G+ LPG +V + +T + +G I V+ +GYF +E+ A
Sbjct: 409 FVNCGRPLPGHEVRIVD-DTDHEVPHMTVGSILVRGGSVMNGYFN-NAEETARAIRPDGW 466
Query: 886 LVTGNTGEVYARTGYLGFLRRTEI 909
L TG+ G ++ Y+ RRT++
Sbjct: 467 LDTGDIGFLFEDDLYITG-RRTDV 489
Score = 46.0 bits (104), Expect = 0.006
Identities = 57/239 (23%), Positives = 97/239 (40%), Gaps = 14/239 (5%)
Query: 10 VACNYTE---GEHMVCVLDFKRETGLWHAVLASVLNGMHVIFIPYALMKVSPASWMHMIT 66
+ CN + G+ L F + GL VLA + + V ++ V P W+ +I+
Sbjct: 233 IVCNGLDVRLGDRCASWLPFYHDMGLVGLVLAPLAAQLSVDYLATRDFAVRPLQWLKLIS 292
Query: 67 KHRASIAIVKSRDLHWGLLATR--DHKEISLSSLRMLLVADGANPWSLSSCDQFLSVFQS 124
++R +IA + L L R D ++ LS R V GA + + F + F +
Sbjct: 293 RNRCTIAFSQPFGLKLCTLRARESDLADLDLSCWRAAGV--GAEMIRMDTLKSFAAKFAA 350
Query: 125 KGVRGDAICPCACSSESMTVCIXXXXXXXXXXXXXVLSMSGLSYGV-VRVDAENSLTSLT 183
G A PC +ES T+ + V + + + + VRV AE +
Sbjct: 351 AGFDERAFLPCYGLAES-TLAVSFPDISRGARSLRVDARTLIEKKIAVRVQAEGRKYN-E 408
Query: 184 LQDCGQVMPSCVIVVVKMEGPAYLCKTDEVGEICVLSGATGSGYWGLPGLTNTVFRVRP 242
+CG+ +P + +V + + VG I V G+ +GY+ T +RP
Sbjct: 409 FVNCGRPLPGHEVRIV--DDTDHEVPHMTVGSILVRGGSVMNGYFN--NAEETARAIRP 463
>UniRef50_Q0V137 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 588
Score = 79.8 bits (188), Expect = 4e-13
Identities = 50/170 (29%), Positives = 87/170 (51%), Gaps = 3/170 (1%)
Query: 736 KGINLACVRTCVVVAEERPRINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASS 795
K ++L ++ ++ + RPR+++ + FS L A++T + +N + +
Sbjct: 7 KTMSLHELKNLMIATDGRPRVDVYSRVRVHFSQAQLDKTAINTVYSHVLNPMVASRSYMC 66
Query: 796 PEPSTVYVDLRALRNDRVSLVERGS-PHSLCLMESGKLLPGVKVITANPETKGQCGDSHL 854
EP +++D+ ALR + V+ + P++L + +SG + ++ NPET C
Sbjct: 67 IEPIELHLDVNALRRGLIMPVDPDTEPNALFVQDSGMVPVSTQISIVNPETNHLCLVGEY 126
Query: 855 GEIWVQSPHNASGYFTIYGDESDYADHFSAQLVTGNTGEVYARTGYLGFL 904
GEIWVQS NA ++ D D A+ F+ + V G+ Y RTG LGFL
Sbjct: 127 GEIWVQSEANAHSFYG-SKDRLD-AERFNGRTVDGDPNVRYVRTGDLGFL 174
Score = 50.4 bits (115), Expect = 3e-04
Identities = 24/54 (44%), Positives = 36/54 (66%), Gaps = 2/54 (3%)
Query: 952 VFVVGALDETIMLRGMRYHPIDIENSVMRCHKKIAE--CAVFTWTNLLVVVVEL 1003
+FV+G++ +T + G+ + +DIE SV RCH+ I CAVF L+VVVVE+
Sbjct: 193 LFVLGSIGDTFEVNGLNHFSMDIEQSVERCHRNIVPGGCAVFQAGGLVVVVVEI 246
Score = 36.7 bits (81), Expect = 3.4
Identities = 29/88 (32%), Positives = 41/88 (46%), Gaps = 3/88 (3%)
Query: 161 LSMSGLSYGVVR-VDAENSLTSLTLQDCGQVMPSCVIVVVKMEGPAYLCKTDEVGEICVL 219
L ++ L G++ VD + +L +QD G V S I +V E +LC E GEI V
Sbjct: 74 LDVNALRRGLIMPVDPDTEPNALFVQDSGMVPVSTQISIVNPE-TNHLCLVGEYGEIWVQ 132
Query: 220 SGATGSGYWGLPG-LTNTVFRVRPLDSD 246
S A ++G L F R +D D
Sbjct: 133 SEANAHSFYGSKDRLDAERFNGRTVDGD 160
>UniRef50_Q93GZ6 Cluster: Non-ribosomal peptide synthetase; n=1;
Streptomyces avermitilis|Rep: Non-ribosomal peptide
synthetase - Streptomyces avermitilis
Length = 1148
Score = 79.4 bits (187), Expect = 5e-13
Identities = 111/451 (24%), Positives = 181/451 (40%), Gaps = 43/451 (9%)
Query: 459 LRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFP 518
+R RA+ V + L + TCAEL A + LL + GD V L+ P
Sbjct: 19 IRARAEREGTAVALSWLTDLKDRTDSRTCAELDDAAAAVAAALLAEAA--PGDRVLLVQP 76
Query: 519 PGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLR 578
PGLD + +F GCLY G VPV + P + VR I S + + ++ + +
Sbjct: 77 PGLDFVTSFVGCLYAGCVPVPVYP--LLDTAEDRAKVRRIQQDSGSRVTWTSDAGM---- 130
Query: 579 SKEASNVLDSKAWPMTLDTDDMPKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHA 638
A V D+ A P T + + +P +P + LA+L ++ +T G+ ++H
Sbjct: 131 ---AEYVADALATPALWRTGE--DRYVP--SESPAPDTLAFLQYTSGSTAEPRGVMVTHG 183
Query: 639 AVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIPPSEVEVNPA 698
+T+ +++ A + L Y +G L +++G H+ L P + NP
Sbjct: 184 NLTANLTAIRDAFRHTADSVVLSWLPAYHDMGLIGNILHPLHTGCHAYLASPIDFIRNPT 243
Query: 699 LWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVVAEERPRINL 758
W +AV Y V + EL + + + L + G++L+ RT AE N
Sbjct: 244 AWPAAVHTYGVTTSGAPDFAYELVARTVDR--DGLPA-GLDLSGWRTAYSGAEP-VSTNT 299
Query: 759 TNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPSTVYVDLRALRNDRVSLVER 818
F++ + G A +G + + ST R R +V
Sbjct: 300 LRRFAEALAPAGFRDDAFVPCYGLAESTLLVTSVPVGAGAST-----RICREGE-EVVTC 353
Query: 819 GSPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNASGYFTIYGDESDY 878
G P + G P G+ +GEI V P A+GY+ + D
Sbjct: 354 GVPRDCEVAVGG--------ADGTPLPAGE-----VGEILVHGPAVAAGYW----NRPDL 396
Query: 879 ADHFSAQLVTGNTGEVYARTGYLGFLRRTEI 909
A V+G + + + RTG LGFL+ E+
Sbjct: 397 TSEVFAANVSG-SDKKWLRTGDLGFLQDGEL 426
Score = 65.7 bits (153), Expect = 6e-09
Identities = 94/391 (24%), Positives = 152/391 (38%), Gaps = 40/391 (10%)
Query: 1 MLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLASVLNGMHVIFIPYALMKVSPAS 60
+ A+ + A +T ++ L + GL +L + G H +P +
Sbjct: 185 LTANLTAIRDAFRHTADSVVLSWLPAYHDMGLIGNILHPLHTGCHAYLASPIDFIRNPTA 244
Query: 61 WMHMITKHRASIAIVKSRDLHWGLLAT---RDHKEISLSSLRMLLVADGANPWSLSSCDQ 117
W + H + + D + L+A RD L GA P S ++ +
Sbjct: 245 WPAAV--HTYGVTTSGAPDFAYELVARTVDRDGLPAGLDLSGWRTAYSGAEPVSTNTLRR 302
Query: 118 FLSVFQSKGVRGDAICPCACSSESMTVCIXXXXXXXXXXXXXVLSMSGLSYGVVRVDAEN 177
F G R DA PC +ES T+ + V +G S + R + E
Sbjct: 303 FAEALAPAGFRDDAFVPCYGLAES-TLLVTS-----------VPVGAGASTRICR-EGEE 349
Query: 178 SLTSLTLQDCGQVMPSCVIVVVKMEGPAYLCKTDEVGEICVLSGATGSGYWGLPGLTNTV 237
+T CG V C + V +G EVGEI V A +GYW P LT+ V
Sbjct: 350 VVT------CG-VPRDCEVAVGGADGTPL--PAGEVGEILVHGPAVAAGYWNRPDLTSEV 400
Query: 238 FRVRPLDSDGEPIGEEHYVRSXXXXXXXXXXXXXXXXSRDGLMTVTGRKHNMDDIIATVL 297
F SD + ++R+ +D ++ V GR H+ DI V+
Sbjct: 401 FAANVSGSD------KKWLRTGDLGFLQDGELHVTGRIKD-VIIVRGRNHHPQDIERLVV 453
Query: 298 AVEPMKFIYRGRIAVFSVRVLRDERICIVAEQRPDCGEEESFQWMSRVLQAVDSIHQVGI 357
+ P + G +A F+ D+ + IVAE RP G+ + +R+ A+ + +
Sbjct: 454 DLCPA--VRPGCVAAFAAP--DDQGVVIVAELRP--GQSLTDDDRARIAGAIATSFGLAP 507
Query: 358 YCLALVQPNFLPKTPLGGIHLSECKRRFLEG 388
+ + V +PKT G + EC+ R+L G
Sbjct: 508 HEIVGVPRGTVPKTTSGKLRRGECRTRYLAG 538
>UniRef50_Q70AY2 Cluster: Acyl-CoA ligase; n=2; Actinoplanes
teichomyceticus|Rep: Acyl-CoA ligase - Actinoplanes
teichomyceticus
Length = 598
Score = 79.0 bits (186), Expect = 6e-13
Identities = 92/407 (22%), Positives = 163/407 (40%), Gaps = 25/407 (6%)
Query: 506 RVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKAT 565
R+ G V L++P GLD + AF+GCLY G + V P P V I ++ +
Sbjct: 63 RLPAGSRVLLLYPNGLDFVAAFFGCLYAGMIAVP--APLPGRYRHHQHRVATISADARVS 120
Query: 566 LVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKKLPIMY--RAPTAEMLAYLDFS 623
VL+ + + +R + LD + + D P+ P + +P +A L ++
Sbjct: 121 AVLTTAAHLGEVRDWARACGLDH----LLIAVGDEPEFGDPAGWTPASPERATIALLQYT 176
Query: 624 VSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGH 683
+TG G+ ++H + + + L Y L ++ G
Sbjct: 177 SGSTGDPKGVVVTHDNILYNLDACVRGLRWPDDWRVGGWLPLYHDLAMQGLLNMAVVRGG 236
Query: 684 HSILIPPSEVEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACV 743
+++L+ P +P WL ++++ ++ TF +LC V + ++L+
Sbjct: 237 YALLMEPVSFVRDPVRWLRTIAEHDIQVTFAPTFAYQLCL----DRVTDEQLAALDLSGW 292
Query: 744 RTCVVVAEE-RPRINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPSTVY 802
+ AE P I +F++ F+ G P + + +G + G P
Sbjct: 293 KIAGNAAEPVNPAI--LAAFAEKFAPAGFRPESFAPIYG-MAEATGYISGEVGRAPLVRT 349
Query: 803 VDLRALRNDRVSLVERGSPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSP 862
V L AL + R++ P ++ G + +PET D LGEIW++
Sbjct: 350 VGLDALAHGRLADPAPDEPVRE-IVSCGTPNEACDIRVVDPETSRVRPDGWLGEIWIRGR 408
Query: 863 HNASGYFTIYGDESDYADHFSAQLVTGNTGEVYARTGYLGFLRRTEI 909
+ GY+ SD F+A G G + RTG LG L+ E+
Sbjct: 409 SVSPGYW------SDAGPAFAAVTAEGEDG--FLRTGDLGVLQDGEL 447
>UniRef50_A0V6T7 Cluster: Amino acid adenylation domain; n=2;
Comamonadaceae|Rep: Amino acid adenylation domain -
Delftia acidovorans SPH-1
Length = 1789
Score = 78.6 bits (185), Expect = 8e-13
Identities = 87/381 (22%), Positives = 154/381 (40%), Gaps = 21/381 (5%)
Query: 530 CLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSK 589
C Y G + V + PP L + IV + A V+S V++ L +A +
Sbjct: 93 CFYAGVIAVPV-PPLESLRVQHLERLLGIVGDADAACVISTAEVMQALPGADARFAGIAA 151
Query: 590 AWPMTLDTDDMPKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKI 649
+D D + P AP A+ +A+L ++ +T G+ +SH + + +++
Sbjct: 152 VAADQVDLADADAWR-P---HAPAADDIAFLQYTSGSTSAPKGVMVSHGNLIANEAAIQQ 207
Query: 650 ACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIPPSEVEVNPALWLSAVSQYKV 709
++ Y +G L +YSG +L P +P WL +S+++
Sbjct: 208 RMDIGAGDRFMSWAPLYHDMGLIGGLLQPLYSGLPLVLTSPRLFLESPVRWLELISRHRA 267
Query: 710 RDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVVAEERPRINLTNSFSKLFSAL 769
+ +C + + S QL ++L+ R AE R + +F++ F+A
Sbjct: 268 TISGGPDFAYRMCLERIKPS--QLAQ--LDLSSWRLAYTGAEP-VRADTVTAFAQRFAAC 322
Query: 770 GLSPRAVSTSFGCRVNIAICLQGASSPEPSTVY-VDLRALRNDRVSLVERGSPHSLCLME 828
GL P A +G ++ + G S +T+ D AL R G+ + L+
Sbjct: 323 GLRPDAAYACYGL-AEASLFITGGSCGAGATITSFDTEALAQGRAE-ESPGASQTTSLVG 380
Query: 829 SGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNASGYFTIYGDESDYADHFSAQLVT 888
G +PG V +P + H+GEIW P + GY +G + Q
Sbjct: 381 CGPAVPGHAVAIVDPHSLQVLEPGHVGEIWAHGPSISQGY---WGKPQQ-----TQQAFV 432
Query: 889 GNTGEVYARTGYLGFLRRTEI 909
+ G + RTG LGF+ ++
Sbjct: 433 EHAGRRWLRTGDLGFVHGGQV 453
Score = 61.7 bits (143), Expect = 1e-07
Identities = 86/379 (22%), Positives = 143/379 (37%), Gaps = 25/379 (6%)
Query: 17 GEHMVCVLDFKRETGLWHAVLASVLNGMHVIFIPYALMKVSPASWMHMITKHRASIAIVK 76
G+ + + GL +L + +G+ ++ L SP W+ +I++HRA+I+
Sbjct: 214 GDRFMSWAPLYHDMGLIGGLLQPLYSGLPLVLTSPRLFLESPVRWLELISRHRATIS--G 271
Query: 77 SRDLHWGLLATR----DHKEISLSSLRMLLVADGANPWSLSSCDQFLSVFQSKGVRGDAI 132
D + + R ++ LSS R L GA P + F F + G+R DA
Sbjct: 272 GPDFAYRMCLERIKPSQLAQLDLSSWR--LAYTGAEPVRADTVTAFAQRFAACGLRPDAA 329
Query: 133 CPCACSSESMTVCIXXXXXXXXXXXXXVLSMSGLSYGVVRVDAENSLTSLTLQDCGQVMP 192
C +E+ L+ G S T+ +L CG +P
Sbjct: 330 YACYGLAEAS--LFITGGSCGAGATITSFDTEALAQGRAEESPGASQTT-SLVGCGPAVP 386
Query: 193 SCVIVVVKMEGPAYLCKTDEVGEICVLSGATGSGYWGLPGLTNTVFRVRPLDSDGEPIGE 252
+ +V L + VGEI + GYWG P T F ++ G
Sbjct: 387 GHAVAIVDPHSLQVL-EPGHVGEIWAHGPSISQGYWGKPQQTQQAF----VEHAG----- 436
Query: 253 EHYVRSXXXXXXXXXXXXXXXXSRDGLMTVTGRKHNMDDIIATVLAVEPMKFIYRGRIAV 312
++R+ +D L+ V G DI V A ++ + +GR+A
Sbjct: 437 RRWLRTGDLGFVHGGQVHVAGRIKD-LIIVRGHNLYPQDIERVVEA--EVEAVRKGRVAA 493
Query: 313 FSVRVLRDERICIVAEQRPDCGEEESFQWMSRVLQ-AVDSIHQVGIYCLALVQPNFLPKT 371
F+V + E I I AE + Q + L AV + + L+ P LP+T
Sbjct: 494 FAVDIDGREGIGIAAEVSFGMQKLVPAQALVDALSTAVGAQCGEAPTVIVLLNPGALPRT 553
Query: 372 PLGGIHLSECKRRFLEGTL 390
G + + C++ + TL
Sbjct: 554 SSGKLQRAACRQGWSARTL 572
>UniRef50_Q0S9C5 Cluster: Fatty-acid--CoA ligase; n=27;
Corynebacterineae|Rep: Fatty-acid--CoA ligase -
Rhodococcus sp. (strain RHA1)
Length = 645
Score = 78.2 bits (184), Expect = 1e-12
Identities = 81/387 (20%), Positives = 159/387 (41%), Gaps = 30/387 (7%)
Query: 510 GDHVALIFPPGLDLICAFYGCLYVGAVPVTI----RPPHPQNLHTTLPTVRMIVDVSKAT 565
GD VA++ P GLD + +F+ ++ G + V + P H LH L D + A
Sbjct: 93 GDRVAVLAPQGLDYVISFFAAIHAGTISVPLFDPDEPGHTDRLHAVLS------DCTPAA 146
Query: 566 LVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKKLPIMYRAPTAEM--LAYLDFS 623
++ + S + ++ L + P + D +P R P ++ +AYL ++
Sbjct: 147 ILTATSSAAGV---RQFFRSLPAAQRPRIIAVDAIPDSVGESWVR-PEIDLDDIAYLQYT 202
Query: 624 VSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGH 683
+T + AG++++H AV + M + EL + L + +G L ++ +
Sbjct: 203 SGSTRVPAGVEITHRAVGTNALQMVDSIELNENSRGVTWLPLFHDMGLLTVILPALGGKY 262
Query: 684 HSILIPPSEVEVNPALWLSAVSQYKV-RDTFCS---YGVMELCTKGLGSSVNQLKSKGIN 739
+I+ P + V+ P W+ ++ TF + + +GL + L +
Sbjct: 263 ITIMSPRAFVQ-RPYRWIKELAAVSDGAGTFAAAPNFAFEHAAARGLPKNGESLDLSNV- 320
Query: 740 LACVRTCVVVAEERPRINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPS 799
++ E + F++ F+ GL A+ S+G S E
Sbjct: 321 -----IGLINGSEPVTTSSMRKFNEAFAPYGLPKTAIKPSYGMAEATLFVSSTRHSDEAR 375
Query: 800 TVYVDLRALRNDRVSLVERGSPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWV 859
+YVD L RV V++ + +++ + G + +PE++ + D +GEIW+
Sbjct: 376 VIYVDRDELNAGRVVKVDQDAENAIPQVSCGYVARSQWAAIVDPESRIEQPDDRVGEIWL 435
Query: 860 QSPHNASGYFTIYGDESDYADHFSAQL 886
+ GY +G + A+ F +L
Sbjct: 436 HGENIGIGY---WGRTDETAETFQNKL 459
Score = 52.8 bits (121), Expect = 5e-05
Identities = 82/327 (25%), Positives = 131/327 (40%), Gaps = 40/327 (12%)
Query: 94 SLSSLRMLLVADGANPWSLSSCDQFLSVFQSKGVRGDAICPCACSSESMTVCIXXXXXXX 153
SL ++ + +G+ P + SS +F F G+ AI P +E+ T+ +
Sbjct: 314 SLDLSNVIGLINGSEPVTTSSMRKFNEAFAPYGLPKTAIKPSYGMAEA-TLFVSSTRHSD 372
Query: 154 XXXXXXVLSMSGLSYG-VVRVD--AENSLTSLTLQDCGQVMPSCVIVVVKMEGPAYLCKT 210
V L+ G VV+VD AEN++ ++ CG V S +V E
Sbjct: 373 EARVIYV-DRDELNAGRVVKVDQDAENAIPQVS---CGYVARSQWAAIVDPESRIEQ-PD 427
Query: 211 DEVGEICVLSGATGSGYWGLPGLTNTVFRVRPLD-------SDGEPIGEEHYVRSXXXXX 263
D VGEI + G GYWG T F+ + + ++G P + +++R+
Sbjct: 428 DRVGEIWLHGENIGIGYWGRTDETAETFQNKLTNRLAEGSHAEGTP-EDANWMRTGDYGV 486
Query: 264 XXXXXXXXXXXSRDGLMTVTGRKHNMDDIIATVLAVEPMKFIYRGRIAVFSVRVLR---- 319
+D L+ V GR H D+ + A E + G +A F+V +
Sbjct: 487 YIDGELFITGRVKD-LVIVDGRNHYPQDLEYS--AQEASTALRPGFVAAFAVPANQLPAV 543
Query: 320 ----------------DERICIVAEQRPDCGEEESFQWMSRVLQAVDSIHQVGIYCLALV 363
E++ IVAE+ P G+ + V A+ S H V + LV
Sbjct: 544 VFENTHSGLNYDAGDSSEQLVIVAERAPGAGKADPQPIADTVRAALSSRHGVTARDILLV 603
Query: 364 QPNFLPKTPLGGIHLSECKRRFLEGTL 390
+P+T G I CK ++EGTL
Sbjct: 604 PAGSIPRTSSGKIARRACKASYIEGTL 630
>UniRef50_A3RUE6 Cluster: Putative uncharacterized protein; n=1;
Ralstonia solanacearum UW551|Rep: Putative
uncharacterized protein - Ralstonia solanacearum UW551
Length = 1084
Score = 77.0 bits (181), Expect = 3e-12
Identities = 90/385 (23%), Positives = 151/385 (39%), Gaps = 22/385 (5%)
Query: 463 AQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLD 522
A+ D V+F G T L +R+ LL E GR GD V L PGL
Sbjct: 12 ARLQPDKVLFEFRTVSGQALARHTYGSLLAAVDRLAALLQEHGRFRHGDRVLLAHRPGLG 71
Query: 523 LICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRS--- 579
I + GC G + V + P + + +R I A VLS+ + + LR
Sbjct: 72 TIVSLLGCARAGLIAVPVALPVRAD-DAAMRRLRAIAVNCSAAAVLSDGAQLSRLRVLLA 130
Query: 580 --KEASNVLDSKAWPMTLDTDDMPKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSH 637
E + + + D D + +P + + + + +L ++ +TG G+ +SH
Sbjct: 131 AWPETAGLAVQDSDVGMADAVDQ-RSSVPRRGASVSPQPVLFLQYTSGSTGQPRGVMVSH 189
Query: 638 AAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIPPSEVEVNP 697
V + R+ + S L + +G + L + +G S + P++ P
Sbjct: 190 RNVIANARA-----TVEDSPVGVSWLPAHHDMGLIGYHLFPLIAGGASYGMAPADFLQTP 244
Query: 698 ALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVVAEERPRIN 757
A WL +S+ + T + C + ++ ++ +GI+L C+R ++ ER R
Sbjct: 245 AAWLRLISEVRATHTSAPDFGYDYCLR--PGKIDAMEIEGIDLGCLR-AMMSGGERVRPA 301
Query: 758 LTNSFSKLFSALGLSPRAVSTSFG-CRVNIAICLQGASSPEPSTVYVDLRALRNDRVSLV 816
F F GL A S+G + + +G S + ALR R +
Sbjct: 302 TVRRFLDRFGRYGLRREACVASYGLAEATLNVAHEGRGS-----LCFSREALREHRAVIA 356
Query: 817 ERGSPHSLCLMESGKLLPGVKVITA 841
G P S+ + GK GV V A
Sbjct: 357 APGEP-SVEIASCGKPASGVLVSIA 380
>UniRef50_Q12275 Cluster: Uncharacterized protein YOR093C; n=3;
Saccharomycetales|Rep: Uncharacterized protein YOR093C -
Saccharomyces cerevisiae (Baker's yeast)
Length = 1648
Score = 77.0 bits (181), Expect = 3e-12
Identities = 74/299 (24%), Positives = 123/299 (41%), Gaps = 26/299 (8%)
Query: 633 IKMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIPPSE 692
+ M+H+++ + + +K +L + + GLGF CL IY+G + L ++
Sbjct: 1189 VTMTHSSLLNASKIVKETLQLRNNSPLFSICSHTSGLGFMFSCLLGIYTGASTCLFSLTD 1248
Query: 693 VEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLAC---------- 742
V +P +L + V+D + + S + K+K N+
Sbjct: 1249 VLTDPKEFLIGLQNLNVKDLYLKLETLYALLDRASSLIEGFKNKKENINSAKNNTSGSLR 1308
Query: 743 ------VRTCVVVAEERPRINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSP 796
VR ++ RPRI + K +S + LS +S + N I L+
Sbjct: 1309 EDVFKGVRNIMIPFPNRPRIYTIENILKRYSTISLSCTQISYVYQHHFNPLISLRSYLDI 1368
Query: 797 EPSTVYVDLRALRNDRVSLV---ERGSPHSLCLMESGKLLPGVKVITANPETKGQCGDSH 853
P +Y+D +LR + V + + + + + +SG + V NPET C D
Sbjct: 1369 PPVDLYLDPFSLREGIIREVNPNDVSAGNYIKIQDSGVVPVCTDVSVVNPETLLPCVDGE 1428
Query: 854 LGEIWVQSPHNASGYFTIYGDESD-YADHF-SAQLVTGNTGEV-----YARTGYLGFLR 905
GEIW S NA YF ++ Y D F + Q + EV Y RTG LGF++
Sbjct: 1429 FGEIWCCSEANAFDYFVCNSSKNKLYKDPFITEQFKSKMKSEVNNTLSYLRTGDLGFIK 1487
>UniRef50_Q0M3P0 Cluster: AMP-dependent synthetase and ligase; n=1;
Caulobacter sp. K31|Rep: AMP-dependent synthetase and
ligase - Caulobacter sp. K31
Length = 577
Score = 75.8 bits (178), Expect = 6e-12
Identities = 85/373 (22%), Positives = 156/373 (41%), Gaps = 18/373 (4%)
Query: 510 GDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPHP-QNLHTTLPTVRMIVDVSKATLVL 568
GD +AL+ + I AF G + G P + PP P + L ++DV++ ++
Sbjct: 66 GDRIALLTQDPEEFIIAFLGAVRAGIAPAPLYPPPPLGGIEIYLSQTVALLDVARPAALI 125
Query: 569 SNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKKLPIMYRAPTAEMLAYLDFSVSTTG 628
+ V+ +++ A LD T+ ++ + P+ + + +L F+ +T
Sbjct: 126 GSAKVLGDIQAAVAG--LDGVKAVATV--QEIRACQAPMTPCEVGPDDVVFLQFTSGSTS 181
Query: 629 MLAGIKMSH-AAVTSLCRSMKIACELYPSRHIALCLDP-YCGLGFALWCLSSIYSGHHSI 686
G+ ++H A V ++ M + + P+R + P Y +G + L +++G +
Sbjct: 182 TPRGVIVTHRALVANIACFMDQSLQADPARDKGVTWLPLYHDMGLIGFVLGPVHTGVSVV 241
Query: 687 LIPPSEVEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTC 746
+P +PA WL A+ Q++ TF L + L + +L+CV+
Sbjct: 242 FMPTVRFAKSPAAWLDALHQHRGTITFAPNFAFALLLRRLRAE----DLGRWDLSCVKAL 297
Query: 747 VVVAEERPRINLTNSFSKLFSALGLSPRAVSTSFG-CRVNIAICLQGASSPEPSTVYVDL 805
AE +L F +F+A GLS A ++G +A+ L+ +P ST VD
Sbjct: 298 GCGAEP-IHPDLIERFLDVFAAAGLSRDAFLPAYGLAEATLAVALRRLGAP-VSTQRVDR 355
Query: 806 RALRNDRVSLVERGSPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNA 865
VS R L + G G ++ +P+ G+IW+ P
Sbjct: 356 ETFERTGVSTPAREDRSWLDHVGFGGPFAGHEIAIRDPD-GAALPHGREGDIWLHGPSVC 414
Query: 866 SGYFTIYGDESDY 878
+GY GDE+ +
Sbjct: 415 AGYL---GDEAGW 424
Score = 46.0 bits (104), Expect = 0.006
Identities = 34/113 (30%), Positives = 50/113 (44%), Gaps = 4/113 (3%)
Query: 24 LDFKRETGLWHAVLASVLNGMHVIFIPYALMKVSPASWMHMITKHRASIAIVKSRDLHWG 83
L + GL VL V G+ V+F+P SPA+W+ + +HR +I +
Sbjct: 218 LPLYHDMGLIGFVLGPVHTGVSVVFMPTVRFAKSPAAWLDALHQHRGTITFAPNFAFALL 277
Query: 84 L--LATRDHKEISLSSLRMLLVADGANPWSLSSCDQFLSVFQSKGVRGDAICP 134
L L D LS ++ L GA P ++FL VF + G+ DA P
Sbjct: 278 LRRLRAEDLGRWDLSCVKAL--GCGAEPIHPDLIERFLDVFAAAGLSRDAFLP 328
>UniRef50_Q83EJ6 Cluster: AMP-binding enzyme family protein; n=2;
Coxiella burnetii|Rep: AMP-binding enzyme family protein
- Coxiella burnetii
Length = 559
Score = 75.4 bits (177), Expect = 8e-12
Identities = 96/454 (21%), Positives = 187/454 (41%), Gaps = 47/454 (10%)
Query: 459 LRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFP 518
L+ R+ + + +++++GA + +T EL++KA + LL + GD L++
Sbjct: 12 LQQRSLEKPSAIAYRIVDSQGATKREITYFELNEKARCLAQLLSQTAA--PGDRAILVYD 69
Query: 519 PGLDLICAFYGCLYVGAVPVTIRPP-HPQN-LHTTLPTVRMIVDVSKATLVLSNQSVIKL 576
I A + CLY G + V PP QN ++ ++ I+ S+ L+L+ Q ++
Sbjct: 70 TDTHFIIALFACLYAGIIAVPAYPPTQIQNRVNVAAYRLKNIILDSEPALLLTTQKFLQF 129
Query: 577 LRSKEAS-NVLDSKAWPMTLDTDDMPKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKM 635
L + L + +T + D+ P +A L ++ +T G+ +
Sbjct: 130 LPEENGQFKKLATDQMNLTGNAPDL----------IPKYSEIALLQYTSGSTSNPKGVMI 179
Query: 636 SHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIPPSEVEV 695
+H + + ++ + + + L +G +++G S+L+ P +
Sbjct: 180 THENIFNNVSNILNLEKPGFLQSVVSWLPLTHDMGIVAGIFLPLFNGIPSVLLSPLDFLR 239
Query: 696 NPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVVAEERPR 755
P +WL +S+ + ELC + VN+++ + +NL+ R E
Sbjct: 240 RPIIWLELISKLPDVISGGPNFAYELCHQ----RVNEVQLRTLNLSHWRV-AFAGSEMNH 294
Query: 756 INLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPSTVYVDLRALRNDRVSL 815
+ F + FSA G +A +G STVY + N V +
Sbjct: 295 VKTYQQFLQKFSACGFDEKAFYPCYGL--------------AESTVYA-TGGVVNAPV-I 338
Query: 816 VERGSPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNASGYFTIYGDE 875
+++ L+ G +++ NP ++ + +GEIW++ P A GY + ++
Sbjct: 339 IDQS------LLSVGHCFKDHELLIVNPNSRQVLSEGTVGEIWLKGPSVAKGY---WKNK 389
Query: 876 SDYADHFSAQLVTGNTGEVYARTGYLGFLRRTEI 909
F A G Y RTG LGF+R+ E+
Sbjct: 390 VLTESVFDAYTHEGK--GPYLRTGDLGFIRKGEL 421
Score = 45.2 bits (102), Expect = 0.010
Identities = 42/178 (23%), Positives = 72/178 (40%), Gaps = 9/178 (5%)
Query: 213 VGEICVLSGATGSGYWGLPGLTNTVFRVRPLDSDGEPIGEEHYVRSXXXXXXXXXXXXXX 272
VGEI + + GYW LT +VF + G Y+R+
Sbjct: 371 VGEIWLKGPSVAKGYWKNKVLTESVFDAYTHEGKGP------YLRTGDLGFIRKGELFFY 424
Query: 273 XXSRDGLMTVTGRKHNMDDIIATVLAVEPMKFIYRGRIAVFSVRVLRDERICIVAEQRPD 332
+D ++ + G+ + +DI V V+ + I +A FS+ E++ IVAE +
Sbjct: 425 GRLKD-IIIIRGKTYPPEDIEWAV--VQSDENIRTASVAAFSILQDDQEKLIIVAEVKGS 481
Query: 333 CGEEESFQWMSRVLQAVDSIHQVGIYCLALVQPNFLPKTPLGGIHLSECKRRFLEGTL 390
E E + + V + I+ + ++ LPKT G I C+ +L+ L
Sbjct: 482 KTENEWRSIFENIRECVSKNFAIKIHEIVCIRAKTLPKTVNGKIQRQICRSAYLDNQL 539
>UniRef50_A2WSZ9 Cluster: Putative uncharacterized protein; n=1;
Oryza sativa (indica cultivar-group)|Rep: Putative
uncharacterized protein - Oryza sativa subsp. indica
(Rice)
Length = 593
Score = 74.9 bits (176), Expect = 1e-11
Identities = 109/433 (25%), Positives = 175/433 (40%), Gaps = 56/433 (12%)
Query: 483 KVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRP 542
+ LT +EL +R+ LLE R GD V ++ PG+ L+ + C G V V + P
Sbjct: 52 ETLTYSELDSAVQRMAAGLLEVLR--RGDTVLVLASPGIRLVKLMFACQRAGLVAVPVIP 109
Query: 543 PHPQNLHTTL--PTVRMI---VDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDT 597
P P + T P R + V ++ +++ + ++ S ++ S W +++D
Sbjct: 110 PDPSVIGTPAEGPAHRHLLRAVSQARPRAAVADPGYVGAVKRSSISALM-SLNW-VSVDR 167
Query: 598 DDMPKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSR 657
+ R P +V+ TG AG A R + A +L P
Sbjct: 168 ----------LERWPAVAS------TVAATGDGAG------AAAHFARPARKAYDLRPGS 205
Query: 658 HIALCLDPY--CGLGFALWCLSSIYSGHHSILIPPSEVEVNPALWLSAVSQYKVRDTFCS 715
+ L Y CGL F L ++ SG +L S P LWL +S++K T
Sbjct: 206 VVVSWLPQYHDCGLMFLLL---TVVSGATCVLTSASAFVRRPRLWLELISEFKATCTPVP 262
Query: 716 YGVMELCTKGLGSSVNQLKSKGINLACVRTCVVVAEERPRINLTNSFSKLFSALGLSPRA 775
+ L + G S + ++ + L +R ++V E + + + F + F GL +
Sbjct: 263 SFALPLVLRR-GRSEHG--TRPLQLQTLRNLILVNEPIYK-SPVDEFLEEFGPAGLRASS 318
Query: 776 VSTSFGCRVNIAICLQGASSPEPSTVYVDLRALRNDRVSLVERGSPHSLCLMESGKLLPG 835
+S S+G N E + L + + L P L E+ P
Sbjct: 319 ISPSYGLAENCTFVSTAWRGTEVT--------LPSYKKLLPSARLPQPSLLTEA----PD 366
Query: 836 VKVITANPETKGQCGDSHLGEIWVQSPHNASGYFTIYGDESDYADHFSAQLVTGNTGEVY 895
V+++ + ET D GEIW+ SP N SGY GD + F A+L G G +
Sbjct: 367 VEIVVVDAETGKLVEDGVEGEIWLSSPSNGSGYL---GDSPASREVFGARL-QGRAGPCF 422
Query: 896 ARTGYLGFLRRTE 908
RT LG + TE
Sbjct: 423 VRTSDLGVVHGTE 435
Score = 41.9 bits (94), Expect = 0.090
Identities = 81/360 (22%), Positives = 134/360 (37%), Gaps = 27/360 (7%)
Query: 36 VLASVLNGMHVIFIPYALMKVSPASWMHMITKHRASIAIVKSRDLHWGLLATR-DH--KE 92
+L +V++G + + P W+ +I++ +A+ V S L L R +H +
Sbjct: 222 LLLTVVSGATCVLTSASAFVRRPRLWLELISEFKATCTPVPSFALPLVLRRGRSEHGTRP 281
Query: 93 ISLSSLRMLLVADGANPWSLSSCDQFLSVFQSKGVRGDAICPCACSSESMTVCIXXXXXX 152
+ L +LR L++ + P S D+FL F G+R +I P +E+ T
Sbjct: 282 LQLQTLRNLILVN--EPIYKSPVDEFLEEFGPAGLRASSISPSYGLAENCTFVSTAWRGT 339
Query: 153 XXXXXXXVLSMSGLSYGVVRVDAENSLTSLTLQDCGQVMPSCVIVVVKMEGPAYLCKTDE 212
++ SY + A SL + P IVVV E L +
Sbjct: 340 ---------EVTLPSYKKLLPSARLPQPSLLTE-----APDVEIVVVDAE-TGKLVEDGV 384
Query: 213 VGEICVLSGATGSGYWGLPGLTNTVFRVRPLDSDGEPIGEEHYVRSXXXXXXXXXXXXXX 272
GEI + S + GSGY G + VF R L P +VR+
Sbjct: 385 EGEIWLSSPSNGSGYLGDSPASREVFGAR-LQGRAGPC----FVRTSDLGVVHGTERYLY 439
Query: 273 XXSR--DGLMTVTGRKHNMDDIIATVLAVEPMKFIYRGRIAVFSVRVLRDERICIVAEQR 330
R D ++ ++ I T + G IA F+ + + +VAE +
Sbjct: 440 VLGRTTDAIVVADSQRRVPAHYIETAAFESSPGRLRGGCIASFTTLPVSPSPVVVVAELQ 499
Query: 331 PDCGEEESFQWMSRVLQAVDSIHQVGIYCLALVQPNFLPKTPLGGIHLSECKRRFLEGTL 390
G + + QAV V + + L + +PKT G + + + L G L
Sbjct: 500 NGGGGGDMAGICHGIRQAVWREVGVTVARVVLAESGGVPKTTSGKLQRGAARAKLLAGKL 559
>UniRef50_UPI0000F2C3ED Cluster: PREDICTED: similar to mKIAA1611
protein; n=1; Monodelphis domestica|Rep: PREDICTED:
similar to mKIAA1611 protein - Monodelphis domestica
Length = 500
Score = 74.1 bits (174), Expect = 2e-11
Identities = 35/66 (53%), Positives = 48/66 (72%)
Query: 945 SHDTHDAVFVVGALDETIMLRGMRYHPIDIENSVMRCHKKIAECAVFTWTNLLVVVVELD 1004
S + + A++VV +LDET+ LRGMRY I IE +++R HK AEC+VFTW NLLV VV+L+
Sbjct: 392 SGEKYGALYVVSSLDETLELRGMRYCLISIEATMIRAHKNNAECSVFTWKNLLVAVVKLE 451
Query: 1005 GNDSEA 1010
+A
Sbjct: 452 DPKQKA 457
>UniRef50_Q127J0 Cluster: AMP-dependent synthetase and ligase; n=5;
Proteobacteria|Rep: AMP-dependent synthetase and ligase
- Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 942
Score = 74.1 bits (174), Expect = 2e-11
Identities = 95/432 (21%), Positives = 178/432 (41%), Gaps = 25/432 (5%)
Query: 446 SDAARKYQFISQILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKG 505
S A + ++L W ++ + N A L+ A+L + A + LL++G
Sbjct: 110 SQAPHAAATLQEVLDWHVRAHPQREHIAIDNGDSAAPTRLSYADLQQGAAGVAAGLLDRG 169
Query: 506 RVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPP-HPQNLHTTLPTVRMIVDVSKA 564
G VAL+ P G + +F G L G +PV I PP + L I+ + A
Sbjct: 170 -FQPGQPVALMLPTGPEYFFSFAGILLAGGIPVPIYPPARAAQIEEHLQRHVGILTNALA 228
Query: 565 TLVLSNQSVIKLLRSKEASNVLDSK--AWPMTLDTDDMPKKKLPIMYRAPTAEMLAYLDF 622
T ++I + R++ + +L S+ + M +++ A +A L +
Sbjct: 229 T------ALITVPRARVLATLLKSQVPSLRMVCTVEELSASTASPERVTAHANDIALLQY 282
Query: 623 SVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSG 682
+ +T G+ ++HA + + R+M A ++ L Y +G L S+Y
Sbjct: 283 TSGSTSSPKGVVLTHANLLANLRAMGQALQVSSEDVFVSWLPLYHDMGLIGAWLGSLYYA 342
Query: 683 HHSILIPPSEVEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLAC 742
+ +++ P P WL AV +++ + ELC + L ++ +G++L+
Sbjct: 343 YPLVVMSPLTFLARPERWLWAVHRHRGTLSGGPNFGYELCLRKL----DEAALEGLDLSS 398
Query: 743 VRTCVVVAEERPRINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPS--- 799
R AE + F + F+ GL P+A++ +G +A G + P
Sbjct: 399 WRFAFNGAEPVSATTM-QEFQQRFACYGLRPQALAPVYG----LAEATLGLTFPPQGRGL 453
Query: 800 -TVYVDLRALRNDRVSLVERGSPHSLCLMES-GKLLPGVKVITANPETKGQCGDSHLGEI 857
+D +A + +L S + L+ + G+ LPG +V + T + + G +
Sbjct: 454 LVDRIDTQAFSHSGRALPAASSTSGVRLVVACGRPLPGHEVRLVD-ATGCEVAERQEGRL 512
Query: 858 WVQSPHNASGYF 869
+ P SGYF
Sbjct: 513 LFKGPSATSGYF 524
Score = 36.7 bits (81), Expect = 3.4
Identities = 54/250 (21%), Positives = 99/250 (39%), Gaps = 13/250 (5%)
Query: 1 MLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLASVLNGMHVIFIPYALMKVSPAS 60
+LA+ R + A + + V L + GL A L S+ ++ + P
Sbjct: 300 LLANLRAMGQALQVSSEDVFVSWLPLYHDMGLIGAWLGSLYYAYPLVVMSPLTFLARPER 359
Query: 61 WMHMITKHRASIAIVKSRDLHWGL-LATRDHKEISLSSLRM---LLVADGANPWSLSSCD 116
W+ + +HR ++ S ++G L R E +L L + +GA P S ++
Sbjct: 360 WLWAVHRHRGTL----SGGPNFGYELCLRKLDEAALEGLDLSSWRFAFNGAEPVSATTMQ 415
Query: 117 QFLSVFQSKGVRGDAICPCACSSESMTVCIXXXXXXXXXXXXXVLSMSGLSYGVVRVDAE 176
+F F G+R A+ P +E+ T+ + + S+ + A
Sbjct: 416 EFQQRFACYGLRPQALAPVYGLAEA-TLGLTFPPQGRGLLVDRI-DTQAFSHSGRALPAA 473
Query: 177 NSLTSLTL-QDCGQVMPSCVIVVVKMEGPAYLCKTDEVGEICVLSGATGSGYWGLPGLTN 235
+S + + L CG+ +P + +V G + + E G + + SGY+ P T
Sbjct: 474 SSTSGVRLVVACGRPLPGHEVRLVDATG-CEVAERQE-GRLLFKGPSATSGYFRNPKETR 531
Query: 236 TVFRVRPLDS 245
+F LDS
Sbjct: 532 RLFDGEWLDS 541
>UniRef50_Q8XRP4 Cluster: Putative amp-dependent synthetase and
ligase transmembrane protein; n=1; Ralstonia
solanacearum|Rep: Putative amp-dependent synthetase and
ligase transmembrane protein - Ralstonia solanacearum
(Pseudomonas solanacearum)
Length = 559
Score = 73.3 bits (172), Expect = 3e-11
Identities = 89/400 (22%), Positives = 163/400 (40%), Gaps = 31/400 (7%)
Query: 511 DHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSN 570
+ V ++ G + F+ CL GAV V P T + V +I + +V
Sbjct: 65 ERVLILCAVGEEYTSVFFACLLAGAVAVPCTPLRGMRHRTKI--VEIIRSCAPRLVVCDE 122
Query: 571 QSVIKLLRSKEASNVLD-SKAWPMTLDTDDMPKKKLPIMYRAPTAEMLAYLDFSVSTTGM 629
S+ L +++ + D + P L ++ + I T+ +A L ++ +T
Sbjct: 123 ASMQPLAALLQSAGLHDVERVAPAGLAAENHAWQPPDI-----TSSDIALLQYTSGSTSD 177
Query: 630 LAGIKMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIP 689
G+ ++HA++ + ++ L P+ + L PY +G LS +Y+G+ L+
Sbjct: 178 PKGVVVTHASIMANLAGIEQKFGLGPASRGMVWLPPYHDMGLIGGVLSPVYTGYPITLLS 237
Query: 690 PSEVEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVV 749
P P WL +SQY++ + + C + V+ + G++L+
Sbjct: 238 PLLFIQKPVRWLRLISQYRITTSGGPNFGYQACVE----RVDDSECAGLDLSTWELAFNG 293
Query: 750 AEERPRINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPSTVYVDLRALR 809
A ER F++ F+ G A ++G + + GA Y L +
Sbjct: 294 A-ERVNAQTLERFTRRFAPYGFRGAAHYPTYGMAESTLMISGGAR----GAGYKVLPEIA 348
Query: 810 NDRVSLVERGSPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNASGYF 869
+ + R + + G L G ++ +P ++ D +GE+WV P A+GY
Sbjct: 349 DSQQGAQFRDA------VSCGSALDGHALLVVDPASRRPVADGAMGEVWVSGPSVAAGY- 401
Query: 870 TIYGDESDYADHFSAQLVTGNTGEVYARTGYLGFLRRTEI 909
+G S+ A H V G G + +TG LG LR E+
Sbjct: 402 --WGHPSE-AFH---GRVEGRAGR-FLQTGDLGVLRDGEL 434
>UniRef50_A4F3K2 Cluster: Non-ribosomal peptide
synthetase/polyketide synthase hybrid enzyme; n=2;
Cyanobacteria|Rep: Non-ribosomal peptide
synthetase/polyketide synthase hybrid enzyme -
Planktothrix agardhii NIVA-CYA 126
Length = 1416
Score = 72.1 bits (169), Expect = 7e-11
Identities = 82/385 (21%), Positives = 162/385 (42%), Gaps = 16/385 (4%)
Query: 489 ELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIR-PPHPQN 547
+L ++A+RI L + G N D V D+I AF+GC+ G +PV + PP +
Sbjct: 215 QLWEQAQRIQTGLQKLGLQNQ-DKVIFQLSENYDIISAFWGCILGGFIPVILSVPPTYKE 273
Query: 548 LHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKKLPI 607
++ + + + ++ + L+++N+S + K+ L ++ P+ L + K P
Sbjct: 274 INHEINKICQVWELLEQPLIITNES--RQQDVKKLEKWLSNQ--PIKLSFIEELKTYSPH 329
Query: 608 MYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIALCLDPYC 667
+ +A+ + + +TGM I ++H + S R I CE Y + I L P+
Sbjct: 330 HSHISQPDDIAFFNLTSGSTGMSKCISLTHKNIISRARGANIICE-YNNDDIILNWLPFD 388
Query: 668 GLG-FALWCLSSIYSGHHSILIPPSEVEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGL 726
+G + + + G + + + P WL + QY++ ++ L + L
Sbjct: 389 HIGSISELHIRCVDLGCQMVYVQTEYILGRPLNWLDLIHQYRITHSWAPNFAYNLINEAL 448
Query: 727 GSSVNQLKSKGINLACVRTCVVVAEERPRINLTNSFSKLFSALGLSPRAVSTSFG-CRVN 785
+Q NL ++ +V E + +KL S L A+ +FG +
Sbjct: 449 KKEPSQT----WNLDSIKFFLVAGEAVSDQVVGEFTNKLHSEYKLKTTAIRPAFGMAEMG 504
Query: 786 IAICLQGASSPEPSTVY-VDLRALRNDRVSLVERGSPHSLCLMESGKLLPGVKVITANPE 844
I ++ +P + VD +L + + V P+S + G +PGV + + E
Sbjct: 505 SGITYYQPTTEQPLLFHTVDKYSLTH-ALKRVHPEHPNSTTFTDLGLPIPGVSIRIVDQE 563
Query: 845 TKGQCGDSHLGEIWVQSPHNASGYF 869
+ +G + V+ + GY+
Sbjct: 564 -NSLLPEEMIGHLQVKGDPVSPGYY 587
>UniRef50_Q5P000 Cluster: CoA ligase, AMP generating; n=2;
Betaproteobacteria|Rep: CoA ligase, AMP generating -
Azoarcus sp. (strain EbN1) (Aromatoleum aromaticum
(strain EbN1))
Length = 831
Score = 70.9 bits (166), Expect = 2e-10
Identities = 102/424 (24%), Positives = 171/424 (40%), Gaps = 33/424 (7%)
Query: 457 QILRWRA--QSTSDHVIFTLLNAKGAVS-KVLTCAELHKKAERIGNLLLEKGRVNTGDHV 513
+ L+W+ DHV+F +A+ A + L A L A RI L+ +G V V
Sbjct: 50 EALQWQVGRNPDRDHVLFYRGDAEQAGEPERLGYAALAADATRIAGGLVRRGVV-PDQCV 108
Query: 514 ALIFPPGLDLICAFYGCLYVGAVPVTIRPP-HPQNLHTTLPTVRMIVDVSKATLVLSNQS 572
AL+ P GLD F+G L+ GA+PV + PP + L I+ +A ++++
Sbjct: 109 ALMLPSGLDFFRCFFGVLFAGAIPVPMYPPARASQIEDHLRRQAGILRNCEAPVLVA--F 166
Query: 573 VIKLLRSKEASNVLDSKAWPMTLDTDDMPKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAG 632
+ LLR VL A + P P A + ++ +TG G
Sbjct: 167 MRPLLR------VLGGLAPSLRHIVTAEELADAPDATPLPARSEAALVQYTSGSTGDPKG 220
Query: 633 IKMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIPPSE 692
+ +SHA + + R+ + + L Y +G L S+Y +L+ P +
Sbjct: 221 VTLSHANLLANIRAYGRVLNVSSTDVCVSWLPLYHDMGLIGAWLGSLYHACPLVLMSPLD 280
Query: 693 VEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVVAEE 752
P WL A+ +++ T ELC K LG G++LA + + AE
Sbjct: 281 FLARPECWLWAIHRHRGTITAAPNFAFELCVKRLGDR----DLAGLDLASWQIAMNGAEP 336
Query: 753 RPRINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPSTVYVDLRALRNDR 812
L F+ F GL ++ +G +A C + P +R R +R
Sbjct: 337 VSAGTL-ERFADAFGRYGLRREILAPVYG----LAECSLALTMTPPGR---GMRTDRIER 388
Query: 813 VSLVERG--SP-----HSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNA 865
++ G SP S+ ++ G LPG +V + + + +G++ + P
Sbjct: 389 AAMTHAGRRSPAGGDTPSVDVVSCGLPLPGHEVRIVGADGR-MLPERRIGQLEFRGPSAT 447
Query: 866 SGYF 869
+GYF
Sbjct: 448 AGYF 451
Score = 44.4 bits (100), Expect = 0.017
Identities = 79/400 (19%), Positives = 156/400 (39%), Gaps = 32/400 (8%)
Query: 1 MLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLASVLNGMHVIFIPYALMKVSPAS 60
+LA+ R N + + V L + GL A L S+ + ++ + P
Sbjct: 228 LLANIRAYGRVLNVSSTDVCVSWLPLYHDMGLIGAWLGSLYHACPLVLMSPLDFLARPEC 287
Query: 61 WMHMITKHRASIAIVK--SRDLHWGLLATRDHKEISLSSLRMLLVADGANPWSLSSCDQF 118
W+ I +HR +I + +L L RD + L+S ++ + +GA P S + ++F
Sbjct: 288 WLWAIHRHRGTITAAPNFAFELCVKRLGDRDLAGLDLASWQIAM--NGAEPVSAGTLERF 345
Query: 119 LSVFQSKGVRGDAICPCACSSE-SMTVCIXXXXXXXXXXXXXVLSMSGLSYGVVRVDAEN 177
F G+R + + P +E S+ + + + + +++ R A
Sbjct: 346 ADAFGRYGLRREILAPVYGLAECSLALTMTPPGRGMRTDR---IERAAMTHAGRRSPAGG 402
Query: 178 SLTSLTLQDCGQVMPSCVIVVVKMEGPAYLCKTDEVGEICVLSGATGSGYWGLPGLTNTV 237
S+ + CG +P + +V +G + +G++ + +GY+ P +
Sbjct: 403 DTPSVDVVSCGLPLPGHEVRIVGADG--RMLPERRIGQLEFRGPSATAGYFRNPAADAAL 460
Query: 238 FRVRPLDSDGEPIGEEHYVRSXXXXXXXXXXXXXXXXSRDGLMTVTGRKHNMDDIIATVL 297
F LD+ G+ Y+ ++D M + G ++ +
Sbjct: 461 FHDGWLDT-----GDFAYL--------VDGELYVTGRAKD--MIIRGGRNFYPYELEQ-- 503
Query: 298 AVEPMKFIYRGRIAVFSV--RVLRDERICIVAEQR-PDCGEEESFQWMSRVLQAVDSIHQ 354
AV + + +G +A F V ER+ +VAE R D ++ + R++ +
Sbjct: 504 AVGELPGVRKGCVAAFGVPDAAPAGERLVVVAEMREKDAAARQALE--QRIVAVSSDVLG 561
Query: 355 VGIYCLALVQPNFLPKTPLGGIHLSECKRRFLEGTLHPSN 394
+ + LV P+ + KT G I + + GTL N
Sbjct: 562 LPADEVVLVPPHAVLKTSSGKIRRGAIREGYRHGTLGTGN 601
>UniRef50_Q1MX62 Cluster: Putative acyltransferase family protein;
n=1; Streptomyces sp. NRRL 11266|Rep: Putative
acyltransferase family protein - Streptomyces sp. NRRL
11266
Length = 584
Score = 70.5 bits (165), Expect = 2e-10
Identities = 86/388 (22%), Positives = 152/388 (39%), Gaps = 20/388 (5%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPH 544
LT AEL ++A L E G V GD V + D +GC +GA+P PP
Sbjct: 62 LTAAELAERAGAAATTLAEHG-VRRGDRVGVCMDTSADAYATLHGCFLLGAIPFVSEPP- 119
Query: 545 PQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMP-KK 603
L T+R + L++S ++ + E + + + + P +
Sbjct: 120 -------LATMRRQRWADRLRLLISRAEPRAVVVAPEFLDAVTEPCKEAGVAIVEPPFEG 172
Query: 604 KLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIALCL 663
L + + +A L F+ TTG G+ ++H ++ + I Y + + +
Sbjct: 173 GLDLATAQAKPDDIALLQFTSGTTGDSRGVTLTHESI--FANATAIGERAYRAGDLIVSW 230
Query: 664 DP-YCGLGFALWCLSSIYSGHHSILIPPSEVEVNPALWLSAVSQYKVRDTFCSYGVMELC 722
P + +G L+ + G +PP V P WL A+ +Y R TF S
Sbjct: 231 LPMHHDMGLIGLNLAPLLHGLPVASMPPLSFAVRPERWLWAMHRY--RGTFTS--APNFA 286
Query: 723 TKGLGSSVNQLKSKGINLACVRTCVVVAEERPRINLTNSFSKLFSALGLSPRAVSTSFG- 781
+ S++ K G++L+ R AE + N F++ +A G R++ +G
Sbjct: 287 YRMCASNIPDAKLAGLDLSAWRVAGNGAEV-VQANTLRLFAERMAAYGYRERSMMPCYGM 345
Query: 782 CRVNIAICLQGASSPEPSTVYVDLRALRNDRVSLVERGSPHSLCLMESGKLLPGVKVITA 841
+ +A + P + R + V E G+ + L+ SG L G+ +
Sbjct: 346 AEITLAATMCEPGEPLTTLTVSRDRLAADGEVVEAEAGAADAQELVSSGTALTGMDLRVV 405
Query: 842 NPETKGQCGDSHLGEIWVQSPHNASGYF 869
+ E D G I +++ SGY+
Sbjct: 406 DDE-GADLPDRRQGTILLRTDSMMSGYY 432
>UniRef50_A3WXS1 Cluster: Probable non-ribosomal peptide synthetase;
n=2; Bradyrhizobiaceae|Rep: Probable non-ribosomal
peptide synthetase - Nitrobacter sp. Nb-311A
Length = 3272
Score = 70.5 bits (165), Expect = 2e-10
Identities = 93/449 (20%), Positives = 171/449 (38%), Gaps = 29/449 (6%)
Query: 459 LRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFP 518
LR D V L G V++ LT AEL ++ + L + G G+ ++ P
Sbjct: 31 LREHVARRPDKVALRFLEQDG-VAEELTFAELDERIRSVAARLQQLG--GAGERAVILLP 87
Query: 519 PGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVS-KATLVLSNQSVIKLL 577
G++ + AFY CLY G + V PP + ++ D + + LV S +
Sbjct: 88 SGINYVVAFYACLYSGVIAVPAYPPEESSARYAGRLNGILRDAAPRFILVESGLCSLVEA 147
Query: 578 RSKEASNV-LDSKAWPMTLDTDDMPKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMS 636
E +NV + + +T D + KL + +A+L ++ +T G+ +S
Sbjct: 148 AFPELTNVQIIAVDSLLTEPAADWRETKL-------ATDAVAFLQYTSGSTSQPKGVCVS 200
Query: 637 HAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIPPSEVEVN 696
H + + R+++ A L Y +G L+ +++G +L+ P
Sbjct: 201 HGNLVANERAIEAAAGGTLDDVFVSWLPLYHDMGLIGGLLNPLFTGFTGVLMSPRNFLER 260
Query: 697 PALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVVAEERPRI 756
P WL A+ ++ + LCT + + ++L+ R E R
Sbjct: 261 PRRWLEAIDRHGGTLSGGPDFAFALCTDRISDEI----IDRLDLSRWR-FAFSGSEFVRH 315
Query: 757 NLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPSTVYVDLRALRNDRVSLV 816
F F+ G + A++ +G + + E + +D L V+
Sbjct: 316 TTVRRFCDRFARAGFNRHALNACYGLAEATLLVTASDGTAETISYTLDTAKLATGVVACA 375
Query: 817 ERGSPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNASGYFTIYGDES 876
+G+ C +++ + + + +GEIWV P GY+ +
Sbjct: 376 SKGTDLVACGRPPAD--HATRIMRVDGSAAAEMDE--VGEIWVTGPSVTLGYW----NNP 427
Query: 877 DYADHFSAQLVTGNTGEVYARTGYLGFLR 905
D + Q+ G + RTG LGF+R
Sbjct: 428 D----ATRQVFVERDGARWLRTGDLGFIR 452
Score = 60.5 bits (140), Expect = 2e-07
Identities = 87/393 (22%), Positives = 146/393 (37%), Gaps = 24/393 (6%)
Query: 1 MLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLASVLNGMHVIFIPYALMKVSPAS 60
++A+ R + A T + V L + GL +L + G + + P
Sbjct: 204 LVANERAIEAAAGGTLDDVFVSWLPLYHDMGLIGGLLNPLFTGFTGVLMSPRNFLERPRR 263
Query: 61 WMHMITKHRASIAIVKSRDLHWGLLATRDHKEI--SLSSLRMLLVADGANPWSLSSCDQF 118
W+ I +H +++ D + L R EI L R G+ ++ +F
Sbjct: 264 WLEAIDRHGGTLS--GGPDFAFALCTDRISDEIIDRLDLSRWRFAFSGSEFVRHTTVRRF 321
Query: 119 LSVFQSKGVRGDAICPCACSSESMTVCIXXXXXXXXXXXXXVLSMSGLSYGVVRVDAENS 178
F G A+ C +E+ + L + L+ GVV ++ +
Sbjct: 322 CDRFARAGFNRHALNACYGLAEA--TLLVTASDGTAETISYTLDTAKLATGVVACASKGT 379
Query: 179 LTSLTLQDCGQVMPSCVIVVVKMEGPAYLCKTDEVGEICVLSGATGSGYWGLPGLTNTVF 238
L CG+ +++++G A + DEVGEI V + GYW P T VF
Sbjct: 380 ----DLVACGRPPADHATRIMRVDGSA-AAEMDEVGEIWVTGPSVTLGYWNNPDATRQVF 434
Query: 239 RVRPLDSDGEPIGEEHYVRSXXXXXXXXXXXXXXXXSRDGLMTVTGRKHNMDDIIATVLA 298
++ DG ++R+ +D ++ V G+ D+ V A
Sbjct: 435 ----VERDG-----ARWLRTGDLGFIRDGALVVAGRLKD-VLIVRGQNIYPTDVEQAVEA 484
Query: 299 VEPMKFIYRGRIAVFSVRVLRDERICIVAE-QRPDCGEEESFQWMSRVLQAVDSIHQVGI 357
++ + RGR+A F+V E I + AE R E+ + QAV Q
Sbjct: 485 --DVESVRRGRVAAFAVEADGQEGIGVAAEFSRAVLKGEDPEVLAEAIGQAVLRQAQEYP 542
Query: 358 YCLALVQPNFLPKTPLGGIHLSECKRRFLEGTL 390
+ L+ P +P T G + S C R TL
Sbjct: 543 AVIVLLNPRAMPLTTSGKLQRSACAARLASNTL 575
Score = 47.2 bits (107), Expect = 0.002
Identities = 57/228 (25%), Positives = 99/228 (43%), Gaps = 18/228 (7%)
Query: 483 KVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRP 542
+ LT A+L KK+ R+ N+L+ +G V VAL + G L GA V + P
Sbjct: 1164 ETLTFADLEKKSNRVANMLIARG-VTREVAVALWIERSPAFVVTLLGVLKAGAAYVPLDP 1222
Query: 543 PHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEAS-NVLDSKAWPMTLDTDDMP 601
P L VR I++ ++L+ + KL S V+D+ A D P
Sbjct: 1223 KWP------LERVRRILNEGHIEILLA--AAEKLTESHVLDCVVIDANAETTNQAISDSP 1274
Query: 602 KKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIAL 661
+ +++ A T AY+ ++ +TG G+ + H A+ + ++ + S +A+
Sbjct: 1275 PE--TVIHPAQT----AYVIYTSGSTGTPKGVAVPHGALANYVQAFLQRLQPQSSASMAM 1328
Query: 662 CLDPYCGLGFALWCLSSIYSGHHSILIPPSEVEVNPALWLSAVSQYKV 709
LG + ++ SG L+ P E ++P + AV + KV
Sbjct: 1329 VSTVAADLGHTV-LFGALASGTTLNLLSP-EAVLDPDAFAQAVGEEKV 1374
>UniRef50_A7TLF5 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 1651
Score = 70.1 bits (164), Expect = 3e-10
Identities = 78/309 (25%), Positives = 130/309 (42%), Gaps = 39/309 (12%)
Query: 635 MSHAAVTSLCRSMKIACELY-PSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIPPSEV 693
M+H ++ C+ +K + +L S ++C + G GF L IY+G + L +
Sbjct: 1190 MTHQSLMKSCKILKESFKLSRESSLFSICGHTF-GFGFLNSVLLGIYTGCQTTLFDIDDF 1248
Query: 694 EVNPALWLSAVSQYKVRDTFCS----YGVMELCTKGLGSSVN-QL------KSKGIN--- 739
NP +L + VRD F + Y +M+ + + SS QL K K N
Sbjct: 1249 SQNPNNFLIGIQNLSVRDLFLTPETFYLIMDRASTLITSSKKIQLAASQKKKQKNSNSST 1308
Query: 740 ------LACVRTCVVVAEERPRINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGA 793
L V+ ++ RP+ + K ++ + ++P +S + R N I ++
Sbjct: 1309 ILRSDFLRNVQNIMIPFSGRPKTLTIENVIKKYNTISINPNQISYIYQNRFNFHISMRSY 1368
Query: 794 SSPEPSTVYVDLRALRNDRVSLV---ERGSPHSLCLMESGKLLPGVKVITANPETKGQCG 850
P + +D R+L+ + + E + + + +SG + V NPET C
Sbjct: 1369 LGIPPVDLLLDPRSLKEGLIKEIDPAELANIEGIRIQDSGVVPICTDVAIVNPETLQPCL 1428
Query: 851 DSHLGEIWVQSPHNASGYFTIYGDESDYADH---FSAQLVT----------GNTGEVYAR 897
+ GEIW S NAS Y+ + D SD F Q +T + G Y R
Sbjct: 1429 EGEFGEIWCCSEGNASDYY-LSKDASDSTSKNRLFKDQFITEQFRSKIKSDKDNGLTYLR 1487
Query: 898 TGYLGFLRR 906
TG LGF++R
Sbjct: 1488 TGDLGFIKR 1496
Score = 39.9 bits (89), Expect = 0.36
Identities = 17/51 (33%), Positives = 32/51 (62%)
Query: 952 VFVVGALDETIMLRGMRYHPIDIENSVMRCHKKIAECAVFTWTNLLVVVVE 1002
++V+G+++ETI + G+ Y D+E++V H I+ C + LLV +V+
Sbjct: 1512 LYVLGSINETIDILGLTYFVSDLESTVRETHSSISNCIITKSGGLLVCLVK 1562
>UniRef50_A7IJ33 Cluster: Amino acid adenylation domain; n=1;
Xanthobacter autotrophicus Py2|Rep: Amino acid
adenylation domain - Xanthobacter sp. (strain Py2)
Length = 3208
Score = 69.7 bits (163), Expect = 4e-10
Identities = 58/273 (21%), Positives = 111/273 (40%), Gaps = 12/273 (4%)
Query: 510 GDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLS 569
G V L+ GLD + AF+GCLY G + V PP M D A
Sbjct: 73 GARVLLLLETGLDYVGAFFGCLYAGLIAVPAFPPEANRPQHQARLAAMARDCGAAI---- 128
Query: 570 NQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKKLP-IMYRAPTAEMLAYLDFSVSTTG 628
+++ A ++L ++ L +++ R P +A+L ++ +T
Sbjct: 129 --ALVHAGDRAAAESLLAAQTGTAVLSVEEVADGDGDGFALRRPRPSDIAFLQYTSGSTS 186
Query: 629 MLAGIKMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILI 688
G+ +SH + + +++ + P + I L Y +G L +++G IL+
Sbjct: 187 TPKGVMVSHGNLIANEIAIRAGFSIQPDKTILSWLPLYHDMGLIGGLLQPLFNGAACILM 246
Query: 689 PPSEVEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVV 748
P P WL A+S+++ + +C + ++ + +G++L+ +
Sbjct: 247 SPRHFLARPVRWLEALSRFRSEVSGGPDFAYRMCVE----RIDPAQVQGLDLSSWKV-AY 301
Query: 749 VAEERPRINLTNSFSKLFSALGLSPRAVSTSFG 781
E R + +F+ F+ LG RAV +G
Sbjct: 302 SGSEPVRASTMEAFAARFAPLGFDARAVHPCYG 334
Score = 41.9 bits (94), Expect = 0.090
Identities = 45/164 (27%), Positives = 69/164 (42%), Gaps = 20/164 (12%)
Query: 483 KVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRP 542
+V + A L +A R+ ++L+ G V V + P G LI A G V P
Sbjct: 1160 QVTSFAALEGEANRLAHVLVAHG-VGPEARVGVGLPRGPGLIAALLAVWKAGGAFVPFDP 1218
Query: 543 PHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPK 602
HP + I+ + TLVL+ + V VLD P +D P
Sbjct: 1219 DHPAE------RIAHILADAGTTLVLAREGVTP------GVPVLD----PDQIDLSSQPA 1262
Query: 603 KKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRS 646
P+ R +E LAYL ++ +TG G+ ++H A+ CR+
Sbjct: 1263 T--PVS-RTAHSEQLAYLVYTSGSTGRPKGVMVAHGALAMHCRA 1303
>UniRef50_Q70C47 Cluster: Polyketide non-ribosomal peptide synthase;
n=2; Xanthomonas albilineans|Rep: Polyketide
non-ribosomal peptide synthase - Xanthomonas albilineans
Length = 6879
Score = 66.9 bits (156), Expect = 3e-09
Identities = 69/287 (24%), Positives = 111/287 (38%), Gaps = 11/287 (3%)
Query: 618 AYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLS 677
A L F+ ++G GI +SH + ++ L H+ L P G L+
Sbjct: 221 ALLLFTSGSSGESKGILLSHRNLHHQIQAGIRQWSLDEHSHVVTWLSPAHNFGLHFGLLA 280
Query: 678 SIYSGHHSILIPPSEVEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKG 737
+SG I P P WL V+ + C + V QL
Sbjct: 281 PWFSGATVSFIHPHSYMKRPGFWLETVAARDATHMAAPNFAFDYCCDWV--MVEQLPPSA 338
Query: 738 INLACVRTCVVVAEERPRINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPE 797
++ T +V E R + F + F+ LG + FG A+ +P+
Sbjct: 339 LSTL---THIVCGGEPVRASTMQRFFEKFAGLGARTQTFMPHFGLSETGALSTLD-EAPQ 394
Query: 798 PSTVYVDLRALRNDRVSLVERGSPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEI 857
+ +D AL N R + S + ++ G + V++ PE + C +GEI
Sbjct: 395 QRVLELDADAL-NKRKRVAAGASQARVTVLNCGAVDQDVELRIVCPEGETLCRPDEIGEI 453
Query: 858 WVQSPHNASGYFTIYGDESDYADHFSAQLVTGNTGEVYARTGYLGFL 904
WV+SP A GY ++ +D + T ++G Y RTG LGF+
Sbjct: 454 WVKSPAIARGY--LFAKPADQRQFNCSIRHTDDSG--YFRTGDLGFI 496
Score = 46.8 bits (106), Expect = 0.003
Identities = 55/215 (25%), Positives = 83/215 (38%), Gaps = 11/215 (5%)
Query: 16 EGEHMVCVLDFKRETGLWHAVLASVLNGMHVIFI-PYALMKVSPASWMHMITKHRASIAI 74
E H+V L GL +LA +G V FI P++ MK P W+ + A+
Sbjct: 258 EHSHVVTWLSPAHNFGLHFGLLAPWFSGATVSFIHPHSYMK-RPGFWLETVAARDATHMA 316
Query: 75 VKSR--DLHWGLLATRDHKEISLSSLRMLLVADGANPWSLSSCDQFLSVFQSKGVRGDAI 132
+ D + +LS+L ++ G P S+ +F F G R
Sbjct: 317 APNFAFDYCCDWVMVEQLPPSALSTLTHIVC--GGEPVRASTMQRFFEKFAGLGARTQTF 374
Query: 133 CPCACSSESMTVCIXXXXXXXXXXXXXVLSMSGLSYGVVRVDAENSLTSLTLQDCGQVMP 192
P SE+ + +++ RV A S +T+ +CG V
Sbjct: 375 MPHFGLSETGALSTLDEAPQQRVLELDADALNKRK----RVAAGASQARVTVLNCGAVDQ 430
Query: 193 SCVIVVVKMEGPAYLCKTDEVGEICVLSGATGSGY 227
+ +V EG LC+ DE+GEI V S A GY
Sbjct: 431 DVELRIVCPEGET-LCRPDEIGEIWVKSPAIARGY 464
>UniRef50_A4BLA6 Cluster: Hypothetical acyltransferase family
protein; n=1; Nitrococcus mobilis Nb-231|Rep:
Hypothetical acyltransferase family protein -
Nitrococcus mobilis Nb-231
Length = 937
Score = 64.9 bits (151), Expect = 1e-08
Identities = 97/420 (23%), Positives = 161/420 (38%), Gaps = 24/420 (5%)
Query: 457 QILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVALI 516
+ L W AQ + K + LT EL ++A + L E+G + D VAL+
Sbjct: 122 EALDWHAQQHPQRTHLYIYGDKEEPEQ-LTYGELDRRASEVAAGLRERG-IGADDTVALM 179
Query: 517 FPPGLDLICAFYGCLYVGAVPVTIRPP-HPQNLHTTLPT-VRMIVDVSKATLVLSNQS-- 572
P D +F G L GAVPV + PP P L L R++ + LV Q+
Sbjct: 180 LPTSRDYFVSFIGILLAGAVPVPLYPPARPTQLEEHLRRHGRILTNAGARVLVTVPQARR 239
Query: 573 VIKLLRSKEASNVLDSKAWPMTLDTDDMPKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAG 632
+ +LL++ EA + +T D P + R + LA L ++ +TG G
Sbjct: 240 IAQLLKA-EAPEL----ECVITADRLAQLPGGRPGLNR--RTDDLAMLQYTSGSTGDPKG 292
Query: 633 IKMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIPPSE 692
I ++H + + R++ E L Y +G S+Y G ++ P
Sbjct: 293 ISLAHKHLLANIRAIGGRIEATSEDFFVSWLPLYHDMGLIGAWFGSLYFGCPLAIMSPLA 352
Query: 693 VEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVVAEE 752
+P WL + +++ + ELC + S +G++L+ R AE
Sbjct: 353 FLAHPLQWLWTIHRHRATLSASPNFGYELCVRAARSGA----LEGMDLSSWRIAFNGAES 408
Query: 753 RPRINLTNSFSKLFSALGLSPRAVSTSFG---CRVNIAICLQGASSPEPSTVYVDLRALR 809
L + F F A GL + +G V + I G P ++ ++ R
Sbjct: 409 VSPATL-DRFYATFRANGLRWETLMPVYGLAEAAVGLTISRPG-RGPWVDAIHREV-FTR 465
Query: 810 NDRVSLVERGSPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNASGYF 869
+ P+ L + G L G +V + + + + G I P SGY+
Sbjct: 466 SGEAQPAAENDPNPLHFVSCGPPLDGYEVRVVDTNDR-ELPERRQGAIQFCGPSATSGYY 524
Score = 40.3 bits (90), Expect = 0.27
Identities = 32/136 (23%), Positives = 60/136 (44%), Gaps = 4/136 (2%)
Query: 1 MLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLASVLNGMHVIFIPYALMKVSPAS 60
+LA+ R + T + V L + GL A S+ G + + P
Sbjct: 300 LLANIRAIGGRIEATSEDFFVSWLPLYHDMGLIGAWFGSLYFGCPLAIMSPLAFLAHPLQ 359
Query: 61 WMHMITKHRASIAIVKSRDLHWGLLATRDH--KEISLSSLRMLLVADGANPWSLSSCDQF 118
W+ I +HRA+++ + + A R + + LSS R + +GA S ++ D+F
Sbjct: 360 WLWTIHRHRATLSASPNFGYELCVRAARSGALEGMDLSSWR--IAFNGAESVSPATLDRF 417
Query: 119 LSVFQSKGVRGDAICP 134
+ F++ G+R + + P
Sbjct: 418 YATFRANGLRWETLMP 433
>UniRef50_A1WAC8 Cluster: AMP-dependent synthetase and ligase; n=1;
Acidovorax sp. JS42|Rep: AMP-dependent synthetase and
ligase - Acidovorax sp. (strain JS42)
Length = 653
Score = 64.9 bits (151), Expect = 1e-08
Identities = 91/403 (22%), Positives = 168/403 (41%), Gaps = 37/403 (9%)
Query: 483 KVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRP 542
+VL+ L ++A + L ++ + GD + L + F+ C+ G VPV + P
Sbjct: 30 RVLSFQRLRQRALAVLGAL-QRQSIAPGDTMILCLADNERFLEMFWACVLGGIVPVPLAP 88
Query: 543 PHPQNLHTTLPTVRMIVDVS-KATLVLSNQSVIKLLRSKEASNVLDSKA-------WPMT 594
L +R+ + KA++ + S+ +L A + D A P
Sbjct: 89 GATDAHRQKL--LRVFAQLGPKASVYIDRTSLERLDGFAAAQGLADQAAALRARALVPGG 146
Query: 595 LDTDDMPKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMK--IACE 652
LD P + P+ +P + LA++ +S +TG G+ ++H +LC ++ I
Sbjct: 147 LDIGGEPGQ--PV---SPRPDDLAFIQYSSGSTGEPKGVLLTH---RNLCANIAAIIEAA 198
Query: 653 LYPSRHIALCLDPYC-GLGFALWCLSSIYSGHHSILIPPSEVEVNPALWLSAVSQYKVRD 711
+ R +AL P +G + L+ + G ++ P LWL SQ +
Sbjct: 199 AFSDRDVALSWMPLSHDMGLIGFHLNMLACGASHAIMRTDLFARRPLLWLDQASQRRA-T 257
Query: 712 TFCSYGVMELCTKGLGSSVNQLKSK---GINLACVRTCVVVAEERPRINLTNSFSKLFSA 768
CS G + Q K G++L+ VR + E +L F++ +
Sbjct: 258 VLCSPNF------GYQHYLRQFALKPPQGLDLSAVR-LIFNGAEPISADLCRRFTQAMAP 310
Query: 769 LGLSPRAVSTSFG-CRVNIAICLQGASSPEPSTVYVDLRALR-NDRVSLVERGSPHSLCL 826
GL P A+ +G ++A+ S+P T+ +D ALR V GS H++
Sbjct: 311 HGLQPNAMFPVYGLAEASLAVSFPPPSTP-LETIELDRTALRVGAPVRAAAPGSTHAIEF 369
Query: 827 MESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNASGYF 869
++ G+ +PG ++ + G D +G + ++ + + GYF
Sbjct: 370 VKLGRAVPGCEIRIVDDAGTG-LADRTVGHVQIRGDNVSGGYF 411
>UniRef50_Q96VP8 Cluster: Putative fatty acid CoA ligase; n=1;
Glomus intraradices|Rep: Putative fatty acid CoA ligase
- Glomus intraradices
Length = 356
Score = 64.1 bits (149), Expect = 2e-08
Identities = 68/257 (26%), Positives = 110/257 (42%), Gaps = 24/257 (9%)
Query: 669 LGFALWCLSSIYSGHHSILIPPSEVEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGS 728
LG L++I G S+++ P P WL ++ Y+ T EL + +
Sbjct: 8 LGLIGGFLNTIRGGCKSVVMSPLTFLQKPESWLQMITNYQATFTAAPNFAYELAARKCDN 67
Query: 729 SVNQLKSKGINLACVRTCVVVAEERPRINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAI 788
N +K+ +NL +R AE R + SF+K F G +G + A
Sbjct: 68 --NSIKN--LNLNSIRGAFNGAEP-VRWSTLKSFAKKFGPAGFKLSMFKCLYGLAEHCAY 122
Query: 789 CLQGASSPE-PSTVYVDLRALRNDRV-----SLVERGSPHSLC--LMESG--KLLPGVKV 838
+ + + P+ + +D LR RV +L + +S ++ +G L+ V+V
Sbjct: 123 SVGFRNLHDIPTVIDIDPIPLREGRVKVRNNTLTNSNNDNSPANNIVSTGVPNLMMQVEV 182
Query: 839 ITANPETKGQCGDSHLGEIWVQSPHNASGYFTIYGDESDYADHFSAQLVTGNTGE----- 893
+ ETK C + +GE+WV SP GY YG E + + F A+L + G
Sbjct: 183 RVVDQETKKLCSPNTIGEVWVSSPSVGKGY---YGKEKNSEETFRAKLDNDDHGNWITDN 239
Query: 894 -VYARTGYLGFLRRTEI 909
+ RTG LGFL E+
Sbjct: 240 GSFLRTGDLGFLYNGEL 256
>UniRef50_P27206 Cluster: Surfactin synthetase subunit 1; n=15;
Bacillus|Rep: Surfactin synthetase subunit 1 - Bacillus
subtilis
Length = 3588
Score = 63.7 bits (148), Expect = 3e-08
Identities = 45/159 (28%), Positives = 75/159 (47%), Gaps = 7/159 (4%)
Query: 486 TCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPHP 545
T EL+ KA R+ +L++ G ++ D V ++ P L++ A G L GA V I P +P
Sbjct: 2570 TYGELNAKANRLARILMDCG-ISPDDRVGVLTKPSLEMSAAVLGVLKAGAAFVPIDPDYP 2628
Query: 546 QNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKKL 605
+ I+ S A L+L + + +LD ++L D+ ++
Sbjct: 2629 DQ------RIEYILQDSGAKLLLKQEGISVPDSYTGDVILLDGSRTILSLPLDENDEENP 2682
Query: 606 PIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLC 644
A TAE LAY+ ++ TTG G+ + H A+ +LC
Sbjct: 2683 ENPETAVTAENLAYMIYTSGTTGQPKGVMVEHHALVNLC 2721
Score = 44.4 bits (100), Expect = 0.017
Identities = 66/272 (24%), Positives = 111/272 (40%), Gaps = 38/272 (13%)
Query: 432 LASAQGRDMGYTDDSDAARKYQFISQILRWRAQSTSDH--VIFTLLNAKGAVSKVLTCAE 489
LA A G+ + Y RK I ++ + +A+ SDH V+F + L+
Sbjct: 447 LARAGGKSVSY-------RKDMTIPELFQEKAELLSDHPAVVFE--------DRTLSYRT 491
Query: 490 LHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLH 549
LH+++ RI N+L +KG V VA++ +I A G L G V I P P
Sbjct: 492 LHEQSARIANVLKQKG-VGPDSPVAVLIERSERMITAIMGILKAGGAYVAIDPGFPAE-- 548
Query: 550 TTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKKLPIMY 609
++ I++ A L+ SK A+ D++ +D D ++
Sbjct: 549 ----RIQYILEDCGADFYLT--------ESKVAAPEADAE----LIDLDQAIEEGAEESL 592
Query: 610 RAP-TAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIALC-LDPYC 667
A A LAY+ ++ TTG G+ + H V L S++ P++ + + L P+
Sbjct: 593 NADVNARNLAYIIYTSGTTGRPKGVMIEHRQVHHLVESLQQTIYQSPTQTLPMAFLPPFH 652
Query: 668 GLGFALWCLSSIYSGHHSILIPPSEVEVNPAL 699
+S+ G ++P V AL
Sbjct: 653 FDASVKQIFASLLLGQTLYIVPKKTVTNGAAL 684
Score = 38.3 bits (85), Expect = 1.1
Identities = 57/244 (23%), Positives = 101/244 (41%), Gaps = 23/244 (9%)
Query: 451 KYQFISQILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTG 510
K + I Q+ +A +T DH T L +G + LT EL+++A R+ +L G G
Sbjct: 1501 KDKTIVQLFEEQAANTPDH---TALQYEG---ESLTYRELNERANRLARGILSLG-AGEG 1553
Query: 511 DHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSN 570
A++ +D+I + L G+ V I P HP + ++ S A ++L+
Sbjct: 1554 RTAAVLCERSMDMIVSILAVLKSGSAYVPIDPEHP------IQRMQHFFRDSGAKVLLTQ 1607
Query: 571 QSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKKLPIMYRAPTAEMLAYLDFSVSTTGML 630
+ + L E V+ + D ++ + + +A L ++ TTG
Sbjct: 1608 RKLKALAEEAEFKGVI------VLADEEESYHADARNLALPLDSAAMANLTYTSGTTGTP 1661
Query: 631 AGIKMSHAAVTSLCRSMKIACEL-YPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIP 689
G ++HA ++ R++K L + L L Y F S+ +G +LIP
Sbjct: 1662 KGNIVTHA---NILRTVKETNYLSITEQDTILGLSNYVFDAFMFDMFGSLLNGAKLVLIP 1718
Query: 690 PSEV 693
V
Sbjct: 1719 KETV 1722
>UniRef50_P72116 Cluster: PAO substrain OT684 pyoverdine gene
transcriptional regulator PvdS; n=2; Pseudomonas
aeruginosa|Rep: PAO substrain OT684 pyoverdine gene
transcriptional regulator PvdS - Pseudomonas aeruginosa
Length = 220
Score = 63.3 bits (147), Expect = 3e-08
Identities = 48/182 (26%), Positives = 76/182 (41%), Gaps = 6/182 (3%)
Query: 457 QILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVALI 516
Q LR RA + + L VL+ +L +A I L + GD L+
Sbjct: 13 QALRRRAVQEPERLALRFLAEDDGEGVVLSYRDLDLRARSIAAAL--QAHAQLGDRAVLL 70
Query: 517 FPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKL 576
FP G D + AF+GCLY G + V PP H + +I D ++ LVL+ + +
Sbjct: 71 FPSGPDYVAAFFGCLYAGVIAVPAYPPESARRHHQERLLSIIAD-AEPRLVLTTADLREP 129
Query: 577 LRSKEASNVLDSKAWPMTLDTDDMPKKKLPIMYRAPT-AEMLAYLDFSVSTTGMLAGIKM 635
L A L + P L D + E +A+L ++ +T + G+++
Sbjct: 130 LLQMNAQ--LSAANAPQLLCVDQLDPAVAEAWDEPQVRPEHIAFLQYTSGSTALPKGVQV 187
Query: 636 SH 637
SH
Sbjct: 188 SH 189
>UniRef50_Q06YY4 Cluster: Acyl-CoA ligase/dehydrogenase fusion
protein; n=1; Streptomyces fungicidicus|Rep: Acyl-CoA
ligase/dehydrogenase fusion protein - Streptomyces
fungicidicus
Length = 1177
Score = 62.9 bits (146), Expect = 4e-08
Identities = 95/448 (21%), Positives = 175/448 (39%), Gaps = 22/448 (4%)
Query: 462 RAQSTSDHVIFTLLNAK-GAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPG 520
RA + TL + GA + +T EL +++ R+ L + R+ G+ V + P G
Sbjct: 18 RADAHPGRTALTLWHGSTGADPESVTYGELARRS-RVRARELAR-RLAPGERVLVALPTG 75
Query: 521 LDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSK 580
++ + CL G V V P P + + I LVL+ + R++
Sbjct: 76 IEFAEVYLACLTAGLVAVP--SPMPGGSASAGERIAAIAADCSPGLVLTTDAA----RAE 129
Query: 581 EASNVLDSKAWPMTLDTDDMPKKKLPIMYRAPTAEMLAYLDFSVSTTGM---LAGIKMSH 637
A ++ + ++ + A ++ A S ST + G+ ++H
Sbjct: 130 VAEHLRGHGPEGLAVEAVLPVGGRSAPGEGADGRDVAAARTRSCSTAPVHRVAEGVILTH 189
Query: 638 AAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIPPSEVEVNP 697
AV + ++ L P L + +G +++ G H L+ P++ P
Sbjct: 190 GAVLANVSAVCTYVGLVPEDRFGSWLPLHHDMGLFTQLTAALLCGAHLTLMTPAQFIRRP 249
Query: 698 ALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVVAEERPRIN 757
A W + ++++ T ELCT+ + + ++G++L+ +R AE
Sbjct: 250 AEWFRMLDRFRITYTVAPNFAYELCTRVITDEM----TRGLDLSALRYLGNGAEP-IHAP 304
Query: 758 LTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPSTVYVD-LRALRNDRVSLV 816
+F + F+ LGL S+ +G + A P+ + VD LR +R L
Sbjct: 305 TVRAFMERFAHLGLRSHVHSSGYGLAESTAYVTCVPEETSPTVLTVDPLRLESGERPELR 364
Query: 817 ERGSPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNASGYFTIYGDES 876
+M G+ + +P + + +GEIW++ GY +G
Sbjct: 365 PVAEGAGRPVMGLGR-PHAFDLRIVDPRERVPLPEGRIGEIWLRGESIGRGY---WGRPE 420
Query: 877 DYADHFSAQLVTGNTGEVYARTGYLGFL 904
A+ F A+L G + RTG LG L
Sbjct: 421 LSAEVFDARLADSAEGPGWLRTGDLGAL 448
Score = 41.5 bits (93), Expect = 0.12
Identities = 52/230 (22%), Positives = 87/230 (37%), Gaps = 11/230 (4%)
Query: 24 LDFKRETGLWHAVLASVLNGMHVIFIPYALMKVSPASWMHMITKHRASIAIVK--SRDLH 81
L + GL+ + A++L G H+ + A PA W M+ + R + + + +L
Sbjct: 215 LPLHHDMGLFTQLTAALLCGAHLTLMTPAQFIRRPAEWFRMLDRFRITYTVAPNFAYELC 274
Query: 82 WGLLATRDHKEISLSSLRMLLVADGANPWSLSSCDQFLSVFQSKGVRGDAICP--CACSS 139
++ + + LS+LR L +GA P + F+ F G+R S
Sbjct: 275 TRVITDEMTRGLDLSALRYL--GNGAEPIHAPTVRAFMERFAHLGLRSHVHSSGYGLAES 332
Query: 140 ESMTVCIXXXXXXXXXXXXXVLSMSGLSYGVVRVDAENSLTSLTLQDCGQVMPSCVIVVV 199
+ C+ + SG +R AE + + G+ + +V
Sbjct: 333 TAYVTCVPEETSPTVLTVDPLRLESG-ERPELRPVAEGA--GRPVMGLGRPHAFDLRIVD 389
Query: 200 KMEGPAYLCKTDEVGEICVLSGATGSGYWGLPGLTNTVFRVRPLDSDGEP 249
E +GEI + + G GYWG P L+ VF R DS P
Sbjct: 390 PRE--RVPLPEGRIGEIWLRGESIGRGYWGRPELSAEVFDARLADSAEGP 437
>UniRef50_A1WAC9 Cluster: AMP-dependent synthetase and ligase; n=3;
Proteobacteria|Rep: AMP-dependent synthetase and ligase
- Acidovorax sp. (strain JS42)
Length = 603
Score = 61.7 bits (143), Expect = 1e-07
Identities = 89/403 (22%), Positives = 149/403 (36%), Gaps = 18/403 (4%)
Query: 472 FTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCL 531
F + + +S VL EL ++A + L GR G +AL+ D FY C
Sbjct: 38 FNYYDGRDKLSAVLPYRELRRRALEMSRRLAPLGR---GQRLALVAHTHPDFAVMFYACQ 94
Query: 532 YVGAVPVTI-RPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKA 590
Y G VPV + H + +R ++ +A + + L EAS L A
Sbjct: 95 YAGLVPVPLPAAVHLGGREAYVRHLRQLMRDCQAVAAFAPSEFVGFL--NEASEGL-PLA 151
Query: 591 WPMTLDTDDMPKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAV-TSLCRSMKI 649
TLD D + + P LAYL ++ +T G ++ +AV +L
Sbjct: 152 LSGTLD-DFLALDAQEKLPPPPAPTDLAYLQYTSGSTRFPRGTMITQSAVMANLGAIFNH 210
Query: 650 ACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIPPSEVEVNPALWLSAVSQYKV 709
L L Y +G L + + +P E + P LWL +S+ +
Sbjct: 211 GFALTADDRFCSWLPHYHDMGLVGIVLGCMATQRSVDYLPTREFAMRPRLWLKLISRNRC 270
Query: 710 RDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVVAEERPRINLTNSFSKLFSAL 769
++ LC + L + ++L+ R V AE +L S++ +
Sbjct: 271 TISYSPPFGYTLCARRL----RPADIEALDLSSWRIAGVGAEMIHPDSL-RQVSEILAPA 325
Query: 770 GLSPRAVSTSFG---CRVNIAICLQGASSPEPSTVYVDLRALRNDRVSLVERGSPHSLCL 826
G RA S+G C + ++ G+ S L R + +
Sbjct: 326 GFDERAFLPSYGMAECALGVSFAPVGSGSRSDLIDIDRLSRTGEARPPIEGEAAVKGKAF 385
Query: 827 MESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNASGYF 869
++ G+ LPG +V + + G I+++ P SGYF
Sbjct: 386 IDCGRPLPGFEV-EVRGDRGNALPERRCGAIYLRGPSVMSGYF 427
>UniRef50_A3IZB3 Cluster: Amino acid adenylation; n=2;
Chroococcales|Rep: Amino acid adenylation - Cyanothece
sp. CCY 0110
Length = 1178
Score = 61.3 bits (142), Expect = 1e-07
Identities = 46/175 (26%), Positives = 85/175 (48%), Gaps = 13/175 (7%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPH 544
LT EL++KA ++ N L G V+ G + L P L+ I G L G + + + P +
Sbjct: 248 LTYQELNQKANQLANYLQTLG-VSNGKFIGLFLEPSLNRIIGLLGILKAGGIYLPLDPTY 306
Query: 545 PQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKK 604
PQ + +++ SK +++L+ K L K ++ SK + D D + ++
Sbjct: 307 PQE------RLNFMIEDSKISILLTQ----KYLNPK--LSIKSSKTINLDTDWDKIEQEF 354
Query: 605 LPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHI 659
+ T E LAY+ ++ +TGM G+ + H A++ C++M + +L S +
Sbjct: 355 CHEVENQTTVENLAYVIYTSGSTGMPKGVLIDHKALSYHCQNMIVYYKLNNSDRV 409
>UniRef50_Q1RS73 Cluster: NRPS/PKS protein; n=5; Bacteria|Rep:
NRPS/PKS protein - Bacillus amyloliquefaciens
Length = 4982
Score = 60.9 bits (141), Expect = 2e-07
Identities = 60/262 (22%), Positives = 108/262 (41%), Gaps = 10/262 (3%)
Query: 455 ISQILRWRAQSTSDHVIFTLLNAKGAVSKVL-TCAELHKKAERIGNLLLEKGRVNTGDHV 513
I ++L A + D T + G +KV T + L K A I L + G V D V
Sbjct: 31 IPEVLHKTAAAAGDQKGITYIQPDG--TKVYQTYSSLKKIALSIVKGLRQSG-VKAQDEV 87
Query: 514 ALIFPPGLDLICAFYGCLYVGAVPVTI-RPPHPQNLHTTLPTVRMIVDVSKATLVLSNQS 572
L LI AF+GC+++GA+PV + P +++ ++ + V++++
Sbjct: 88 ILQLSDNSQLIPAFWGCVFLGAIPVPLAAAPAYTEMNSGTQKLKDAWTLLNQPYVITSRD 147
Query: 573 VIKLLRSKEASNVLDSKAWPMTLDTDDMPKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAG 632
V+ + L L +D+ ++ P E LA L + +TG
Sbjct: 148 VLPEMTEWAEEQGLSGFC---ALAAEDLSAHEMDTDCHHPRPEDLAMLLLTSGSTGTPKA 204
Query: 633 IKMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGL-GFALWCLSSIYSGHHSILIPPS 691
+ +SH + + + I + Y S + P+ + G + L +Y G I IP
Sbjct: 205 VMLSHENIVCMVKG-NIQMQGYTSEDVTFNWMPFDHVGGIGMLHLRDVYLGCEEINIPSE 263
Query: 692 EVEVNPALWLSAVSQYKVRDTF 713
+ ++P WL + Y+ T+
Sbjct: 264 SILMDPLKWLDLIDHYRASVTW 285
>UniRef50_Q83AH1 Cluster: Acyltransferase family protein; n=4;
Coxiella burnetii|Rep: Acyltransferase family protein -
Coxiella burnetii
Length = 853
Score = 60.1 bits (139), Expect = 3e-07
Identities = 97/455 (21%), Positives = 177/455 (38%), Gaps = 38/455 (8%)
Query: 451 KYQFISQILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTG 510
K + + ++L AQ+ D N G + ++ EL+ +A+ L+ KG +
Sbjct: 26 KVETLVELLNLYAQNEPDRPHIYFQNEFGEET-IIRYGELYTRAKEFAQGLVGKG-LKPS 83
Query: 511 DHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSN 570
+ VA++ P D +F G L G +PV I PP + ++ + +L N
Sbjct: 84 ETVAIMLPTSADFFYSFLGTLMAGGIPVPIYPPFRAD--------QIEEYAKREAFILHN 135
Query: 571 QSVIKLLRSKEA---SNVLDSKAWPMTLDTDDMPKKKLPIMYRAPTAEMLA----YLDFS 623
V L+ K A S +L S P L+ + K I PT ++ A + ++
Sbjct: 136 AGVRFLITFKRAAALSKLLQSFV-PSLLEVTTV-KALTDISADLPTLDIEATDPVLIQYT 193
Query: 624 VSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGH 683
+TG G+ ++HA + + + + + L Y +G + S Y G
Sbjct: 194 SGSTGNPKGVLLNHANLLANISAYGKTLNMQSTDAFVSWLPLYHDMGLIGAWMGSFYHGL 253
Query: 684 HSILIPPSEVEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACV 743
L+ P P WL A+ ++ + +LC K + S +G++L+
Sbjct: 254 PLTLLSPFTFLSRPEKWLWAIHYHRGTISPGPNFAYDLCVKKIEDS----DLEGLDLSSW 309
Query: 744 RTCVVVAEERPRINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPE----PS 799
R + +E L N F K F G A+ ++G +A C G + P P+
Sbjct: 310 RVALNGSEMIHPDTLRN-FEKRFRKYGFKKEAIFPAYG----LAECALGLTFPPLNRGPN 364
Query: 800 TVYVDLRAL--RNDRVSLVERGSPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEI 857
++ N V L R + + G +L G ++ + + + + +G I
Sbjct: 365 IDRIERLPYEKNNTAVPLTTRDKKY-YEFVSCGSVLEGHEIRIVD-DNDNRVAERTIGNI 422
Query: 858 WVQSPHNASGYFTIYGDESDYADHFSAQLVTGNTG 892
+ P GY+ E+ A + + TG+ G
Sbjct: 423 QFKGPSAMQGYYR--NSEATMAIYHNGWWATGDLG 455
Score = 36.3 bits (80), Expect = 4.5
Identities = 34/116 (29%), Positives = 56/116 (48%), Gaps = 11/116 (9%)
Query: 279 LMTVTGRKHNMDDIIATVLAVEPMKFIYRGRIAVFSVRVLR--DERICIVAEQRPDCGEE 336
L+ GR ++ +I A E ++ + +A F V + E++ IVAE + D +
Sbjct: 471 LIIKAGRNYHPTEIEAMASLAEGVR---KSCVAAFGVADEKRGTEKLIIVAETKEDKKIQ 527
Query: 337 ESFQWMSRVLQAVDSIHQVGIYC--LALVQPNFLPKTPLGGIHLSECKRRFLEGTL 390
+ ++ V I Q+GI + LV P+ LPKT G + S CK+ +L G L
Sbjct: 528 PEIK--KEIVDKV--ISQIGIPPDEILLVPPHTLPKTSSGKLRRSSCKQDYLAGKL 579
>UniRef50_A7IE19 Cluster: AMP-dependent synthetase and ligase; n=2;
Proteobacteria|Rep: AMP-dependent synthetase and ligase
- Xanthobacter sp. (strain Py2)
Length = 1976
Score = 59.7 bits (138), Expect = 4e-07
Identities = 96/399 (24%), Positives = 167/399 (41%), Gaps = 27/399 (6%)
Query: 446 SDAARKYQFISQILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKG 505
+DAAR +++ L A+ D I L G S+ LT A L ++A RI L G
Sbjct: 539 ADAART---LTEALLRTAERAGDKGI--LFEGTGP-SRRLTYATLLEEARRIAGGLKAAG 592
Query: 506 RVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKAT 565
+ GD L + AF+GC+ G PVT+ T L + + A
Sbjct: 593 -LEPGDMAILQVADLRAHLPAFWGCVLAGVKPVTVAVSATFTERTAL-----VAKLINAW 646
Query: 566 LVLSNQSVIK--LLRSKEASNVLDSKAWPMTLDTDDMPKKK-LPIMYRAPTAEMLAYLDF 622
+L V+ L S A + A P L + + L ++ A A++L +L
Sbjct: 647 ELLGRPVVLAPAALASPLAGLARFADAAPRVLALEQLADHPPLEAVHAAAPADVL-FLQL 705
Query: 623 SVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFAL-WCLSSIYS 681
S +TG I+++H V + + + Y + +AL P + L W L +Y
Sbjct: 706 SSGSTGTPKCIQITHGGVVAHIHAT-VRVNGYGADDVALNWLPMDHVVPMLTWHLRDVYL 764
Query: 682 GHHSILIPPSEVEVNPALWLSAVSQYKV-RDTFCSYGVMELCTKGLGSSVNQLKSKGINL 740
G I + + V +P LWL + ++ V R ++G K + ++ + + L
Sbjct: 765 GMTQIQVETAAVLADPLLWLDLMDRHGVTRSWSPNFGF-----KLVSDALRRDPGRRFAL 819
Query: 741 ACVRTCVVVAEERPRINLTNSFSKLFSALGLSPRAVSTSFG-CRVNIAICLQGASSPEPS 799
VRT ++ A E+ + + + F L + GL A+ +FG + + P S
Sbjct: 820 GHVRT-LMNAGEQATLPVISEFLALTAPFGLRAEAMQPAFGMAEACTCMTYETGFDPARS 878
Query: 800 TVYVDLRALRNDRVSLVERGSPHSLCLMESGKLLPGVKV 838
++D +A R+ V +P ++ ++ G +PGV +
Sbjct: 879 VHWID-KASLGGRLRPVAADAPEAVSFIKLGPPVPGVAI 916
>UniRef50_A7GTF8 Cluster: Beta-ketoacyl synthase; n=3; cellular
organisms|Rep: Beta-ketoacyl synthase - Bacillus cereus
subsp. cytotoxis NVH 391-98
Length = 3099
Score = 59.3 bits (137), Expect = 6e-07
Identities = 88/444 (19%), Positives = 175/444 (39%), Gaps = 16/444 (3%)
Query: 451 KYQFISQILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTG 510
K + I ++L A D I + N V L+ L +A R L +KG + G
Sbjct: 26 KKENIGRLLMEAADERKDSGITFIQN--DGVEDFLSYESLLNRAVRCLGGLQKKG-IQQG 82
Query: 511 DHVALIFPPGLDLICAFYGCLYVGAVPV-TIRPPHPQNLHTTLPTVRMIVDVSKATLVLS 569
HV L+ D I +F+ C+ G +PV + P + ++ L + ++ ++ + ++LS
Sbjct: 83 QHVMLVLEDSRDFIISFWACILGGIIPVPLVYPTSLKMKNSILDKLFVVWNLLEKPVILS 142
Query: 570 NQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKKLPIMYRAPTAEMLAYLDFSVSTTGM 629
+ V+ ++ ++L K + + + AP ++ A++ FS +T +
Sbjct: 143 DDHVVN--HHEKIESLLAVKGMEFLSISTLYSANEGGEINLAP-SDTPAFIQFSSGSTSV 199
Query: 630 LAGIKMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIP 689
G+ ++H + + +M L + + +G + L G H +
Sbjct: 200 PKGVILTHRNLLTNIEAMIAGIHLNHEDKSFSWMPYHHDMGLIGFHLVPTAKGIHQFNMS 259
Query: 690 PSEVEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVV 749
P + P LWL ++++++ T G + L S + + K +L +R +
Sbjct: 260 PMKFVKRPNLWLDYITKHRITLT----GSPNFGYRLLLSRAKEEQFKKWDLRSLR-LIFN 314
Query: 750 AEERPRINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPSTVYVDLRALR 809
E ++L F L A+ +G + EP ++ + L
Sbjct: 315 GAEPISVSLMREFMSKLKQCHLRKEAMFPVYGMAEACLAVSFPKWNDEPFVNCINRKTLV 374
Query: 810 ND-RVSLVERGSPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNASGY 868
++ RV ++ L+E G + G+K+ + E + +GE+ + + GY
Sbjct: 375 SESRVEKCLETDRQAMLLVEEGSPVAGMKIRIVD-EVGNVVPEGIVGEVQIYGENVTDGY 433
Query: 869 FTIYGDESDYADHFSAQLVTGNTG 892
IY D L TG+TG
Sbjct: 434 --IYNDRVTKESIQDGWLKTGDTG 455
Score = 39.1 bits (87), Expect = 0.63
Identities = 32/113 (28%), Positives = 52/113 (46%), Gaps = 4/113 (3%)
Query: 24 LDFKRETGLWHAVLASVLNGMHVIFIPYALMKVSPASWMHMITKHRASIAIVKSRDLHWG 83
+ + + GL L G+H + P W+ ITKHR I + S + +
Sbjct: 233 MPYHHDMGLIGFHLVPTAKGIHQFNMSPMKFVKRPNLWLDYITKHR--ITLTGSPNFGYR 290
Query: 84 LLATRDHKE-ISLSSLRML-LVADGANPWSLSSCDQFLSVFQSKGVRGDAICP 134
LL +R +E LR L L+ +GA P S+S +F+S + +R +A+ P
Sbjct: 291 LLLSRAKEEQFKKWDLRSLRLIFNGAEPISVSLMREFMSKLKQCHLRKEAMFP 343
>UniRef50_Q5CUM8 Cluster: Type I fatty acid synthase; n=4;
Cryptosporidium|Rep: Type I fatty acid synthase -
Cryptosporidium parvum Iowa II
Length = 8243
Score = 58.8 bits (136), Expect = 7e-07
Identities = 51/250 (20%), Positives = 109/250 (43%), Gaps = 16/250 (6%)
Query: 663 LDPYCGLGFALWCLSSIYSGHHSILIPPSEVEVNPALWLSAVSQYKVRDTFCSYGVMELC 722
L Y +G + + ++ G + + P + P LW+ + +Y + E+
Sbjct: 349 LPVYHDMGLIGFFCTPLFFGCNIFQMSPIDFIKKPYLWMQCMDKYNCSVSGAPNFAFEVV 408
Query: 723 TKGLGSSV-NQLKSKGINLACVRTCVVVAEERPRINLTNSFSKLFSALGLSPRAVSTSFG 781
+ + NQL K + ++ E R + F++ F ++G+ + ++G
Sbjct: 409 VRKTPKEILNQLNLKHV------FAILSGAEPIRKTTIDRFTEAFKSVGIKHNVIKPAYG 462
Query: 782 CRVNIAICLQGASS--PEPSTVYVDLRALRNDRVSLV----ERGSPHSLCLMESGKLLPG 835
+ I + G++S E + + V+ + LR + + E+ S + + SG + G
Sbjct: 463 LAEHTLI-VAGSNSFQQEVNHITVNTKKLREKNIVEIKEAKEKSSTETTSFVSSGIVYKG 521
Query: 836 VKVITANPETKGQCGDSHLGEIWVQSPHNASGYFTIYGDESDYADHFSAQLVTGNTGE-V 894
+ + NPE+ + ++GEIW+ S GY+ +E++ + + ++ G T +
Sbjct: 522 IDLRIVNPESLKEVTPGNVGEIWISSESVTLGYYN-NKEETEKTFNANFTMLDGKTSKST 580
Query: 895 YARTGYLGFL 904
Y RTG GF+
Sbjct: 581 YMRTGDSGFI 590
Score = 51.2 bits (117), Expect = 1e-04
Identities = 28/104 (26%), Positives = 47/104 (45%)
Query: 472 FTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCL 531
++ + + G + K T E +K + L +K + GD V L + PG D + AF CL
Sbjct: 66 YSWIGSNGDIKKKFTYREFFEKVVELSWYLSKKLGIKAGDKVILCYTPGYDFVIAFTTCL 125
Query: 532 YVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIK 575
G V V + PP P + + I S+ + L+ S ++
Sbjct: 126 VSGIVAVPVYPPDPMRGQSEIQRFCDIKQASETNISLTCTSYMR 169
Score = 49.2 bits (112), Expect = 6e-04
Identities = 78/382 (20%), Positives = 149/382 (39%), Gaps = 25/382 (6%)
Query: 58 PASWMHMITKHRASIAIVKSRDLHWGLLATRDHKEI--SLSSLRMLLVADGANPWSLSSC 115
P WM + K+ S++ + + + ++ + KEI L+ + + GA P ++
Sbjct: 383 PYLWMQCMDKYNCSVS--GAPNFAFEVVVRKTPKEILNQLNLKHVFAILSGAEPIRKTTI 440
Query: 116 DQFLSVFQSKGVRGDAICPCACSSESMTVCIXXXXXXXXXXXXXVLSMSGLSYGVVRVD- 174
D+F F+S G++ + I P +E + V + +V +
Sbjct: 441 DRFTEAFKSVGIKHNVIKPAYGLAEHTLIVAGSNSFQQEVNHITVNTKKLREKNIVEIKE 500
Query: 175 -AENSLTSLT-LQDCGQVMPSCVIVVVKMEGPAYLCKTDEVGEICVLSGATGSGYWGLPG 232
E S T T G V + +V E + VGEI + S + GY+
Sbjct: 501 AKEKSSTETTSFVSSGIVYKGIDLRIVNPESLKEV-TPGNVGEIWISSESVTLGYYNNKE 559
Query: 233 LTNTVFRVRPLDSDGEPIGEEHYVRSXXXXXXXXXXXXXXXXSRDGLMTVTGRKHNMDDI 292
T F DG+ + Y+R+ +D ++ + GR DI
Sbjct: 560 ETEKTFNANFTMLDGK-TSKSTYMRTGDSGFIINDMLYISGRIKD-MIIIRGRNFYPQDI 617
Query: 293 IATVLAVEPMKFIYRGRIAVFSV-RVLRDERICIVAEQRPDCG---------EEESFQWM 342
+ V ++ +G +AVFSV + +E I + E R + E+ ++ +
Sbjct: 618 EEVIDGVSGVR---QGSVAVFSVTQADGEEAIGVAVEIRMETSILGRVRRFFEKPAYDNI 674
Query: 343 SRVL-QAVDSIHQVGIYCLALVQPNFLPKTPLGGIHLSECKRRFLEGTLHPSNVLMCPHT 401
R + +AV H + ++ + L+ P + KT G I S+ + L P +C +
Sbjct: 675 VRAISKAVFIGHGLPVHYIWLLSPRTILKTSSGKIRRSQTRDAIFSKKLVPLFEWVCEQS 734
Query: 402 CVTNLPKPREIHSDVGPASVIV 423
++++ R + P S+I+
Sbjct: 735 PMSDILVERS-SQFISPTSMII 755
>UniRef50_Q9A929 Cluster: Acyl-CoA synthetase; n=4;
Alphaproteobacteria|Rep: Acyl-CoA synthetase -
Caulobacter crescentus (Caulobacter vibrioides)
Length = 567
Score = 58.4 bits (135), Expect = 1e-06
Identities = 83/400 (20%), Positives = 153/400 (38%), Gaps = 18/400 (4%)
Query: 474 LLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYV 533
L + +G + + L A+L +A + LL G GD VAL+ D + AF+ C Y
Sbjct: 35 LYSLRGELVEALPYAKLRDEAVVLARRLLAIG-AKVGDSVALLAETDGDFVRAFFACQYA 93
Query: 534 GAVPVTIRPPHPQN-LHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWP 592
G +P + P P + + + +KA +++ + + A L
Sbjct: 94 GLLPAPMALPTPLGGREAYIEQISNLARSAKANILIGPVGLKDWVAEIGARAGLAFAG-- 151
Query: 593 MTLDTDDMPKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSM-KIAC 651
+ D + LP + T E YL FS +T G+ + H A+ + C ++ +
Sbjct: 152 VLADLPEDAGAALPTI----TPEDPCYLQFSSGSTRTPTGVLVRHKALMANCVAITRDGL 207
Query: 652 ELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIPPSEVEVNPALWLSAVSQYKVRD 711
++ S L Y +G + LS + L+P P LW+ + + K
Sbjct: 208 QVRASDRAISWLPLYHDMGLIGFLLSPLSCQMTVDLLPTGAFVRRPLLWIDLIGRNKATI 267
Query: 712 TFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVVAEERPRINLTNSFSKLFSALGL 771
+ ELC + V + NL+ R+ + + R+ +F + F+ G
Sbjct: 268 AYSPTFGYELCAR----RVQGQSLENYNLSHWRS-AGLGGDMIRMPPLKAFVEAFAPAGF 322
Query: 772 SPRAVSTSFG-CRVNIAICLQGASSPEPSTVYVDLRALRNDRVSL-VERGSPHSLCLMES 829
S +A S+G +A+ + + +D+ L D +++ GS +
Sbjct: 323 SDKAFVASYGMAEATLALSMAPLGKGLRAET-LDVERLERDALAVDAPEGSERARDFARC 381
Query: 830 GKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNASGYF 869
G LP + + + +G I+ + P S YF
Sbjct: 382 GPALPD-HFLEVRGDDGQVLPERGVGRIFAKGPSVMSAYF 420
>UniRef50_Q1JTE1 Cluster: Type I fatty acid synthase, putative; n=3;
root|Rep: Type I fatty acid synthase, putative -
Toxoplasma gondii RH
Length = 9940
Score = 58.4 bits (135), Expect = 1e-06
Identities = 75/308 (24%), Positives = 125/308 (40%), Gaps = 33/308 (10%)
Query: 106 GANPWSLSSCDQFLSVFQSKGVRGDAICPCACSSESMTVCIXXXXXXXXXXXXXVLSMSG 165
GA P S+ D+F F KGVR A+CP +ES T+ + ++
Sbjct: 302 GAEPIRASTIDRFCEKFGPKGVRRCAVCPAYGLAES-TLIVTARKTFQTVPKLLIVDSFQ 360
Query: 166 LSY--GVVRVDAENSLTS-----LTLQDCGQVMPSCVIVVVKMEGPAYLCKTDEVGEICV 218
L + VV + E ++T L CG + + +V E L +VGEI V
Sbjct: 361 LQHEKTVVALKPEATVTMDSEEYQVLVGCGVPLEGVQVRIVDPETKKEL-PPGKVGEIVV 419
Query: 219 LSGATGSGYWGLPGLTNTVFRVRPLDSDGE---PIGEEHYVRSXXXXXXXXXXXXXXXXS 275
S + GY+G P T F D G+ P+G +R+
Sbjct: 420 YSSSVARGYFGRPDTTKETFCYSFTDLQGKQTPPLG----MRTGDGGFMYEGELFVAARL 475
Query: 276 RDGLMTVTGRKHNMDDIIATVLAVEPMKFIYRGRIAVFSVRVLRDERICIVAEQRPDCG- 334
+D L+ + GR DI AV+ + + G A F++ V E + + AE R + G
Sbjct: 476 KD-LIIIRGRNFYPQDIEE---AVDKVAMVRPGSSAAFAIEVDGHEALAVAAEVRLEEGI 531
Query: 335 -----------EEESFQWMSR-VLQAVDSIHQVGIYCLALVQPNFLPKTPLGGIHLSECK 382
+ ++ + R + ++V + + I+ + L++P +PKT G + S K
Sbjct: 532 KGLWLRVKRQFDRSHYEQIVRDISKSVAANTGLTIHRIWLLRPRTIPKTSSGKVRRSLTK 591
Query: 383 RRFLEGTL 390
+ + G L
Sbjct: 592 EKLVSGKL 599
Score = 48.0 bits (109), Expect = 0.001
Identities = 60/256 (23%), Positives = 99/256 (38%), Gaps = 15/256 (5%)
Query: 663 LDPYCGLGFALWCLSSIYSGHHSILIPPSEVEVNPALWLSAVSQYKVRDTFCSYGVMELC 722
L Y +G + S I G + P + P LWL +S+Y E+
Sbjct: 220 LPVYHDMGLIGFVCSPILCGATLYQMSPIDFIRRPWLWLQGMSKYDCICCAAPNFAFEVV 279
Query: 723 TKGLGSSVNQLKSKGINLACVRTCVVVAEERP-RINLTNSFSKLFSALGLSPRAVSTSFG 781
T+ + +V + +L R C ++ P R + + F + F G+ AV ++G
Sbjct: 280 TRKMPDNVYE------HLDLSRVCGFLSGAEPIRASTIDRFCEKFGPKGVRRCAVCPAYG 333
Query: 782 -CRVNIAICLQGASSPEPSTVYVDLRALRNDRV-------SLVERGSPHSLCLMESGKLL 833
+ + + P + VD L++++ + V S L+ G L
Sbjct: 334 LAESTLIVTARKTFQTVPKLLIVDSFQLQHEKTVVALKPEATVTMDSEEYQVLVGCGVPL 393
Query: 834 PGVKVITANPETKGQCGDSHLGEIWVQSPHNASGYFTIYGDESDYADHFSAQLVTGNTGE 893
GV+V +PETK + +GEI V S A GYF + + L T
Sbjct: 394 EGVQVRIVDPETKKELPPGKVGEIVVYSSSVARGYFGRPDTTKETFCYSFTDLQGKQTPP 453
Query: 894 VYARTGYLGFLRRTEI 909
+ RTG GF+ E+
Sbjct: 454 LGMRTGDGGFMYEGEL 469
>UniRef50_Q0C1U0 Cluster: Putative AMP binding protein; n=1;
Hyphomonas neptunium ATCC 15444|Rep: Putative AMP
binding protein - Hyphomonas neptunium (strain ATCC
15444)
Length = 591
Score = 58.0 bits (134), Expect = 1e-06
Identities = 82/398 (20%), Positives = 161/398 (40%), Gaps = 34/398 (8%)
Query: 485 LTCAELHK--KAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRP 542
LTC+ ++ K + +G R G + +I + + F C Y G VP +
Sbjct: 55 LTCSLSYRELKDQALGVAARMAARFPRGARIGVIAETSPEFVITFMACQYSGLVPAPLSL 114
Query: 543 PHPQNLHTTLP-TVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMP 601
P T V +V + + + + ++ ++L S A ++ L +P
Sbjct: 115 PAAFGGRQTYEWQVSSMVRTAGLSAIFAPPALHEILSSATAGQDIEL----FDLSGATLP 170
Query: 602 KKKL-PIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRS-MKIACELYPSRHI 659
+ + P+ + A L+Y+ FS +T GI + A++++ C++ ++ ++
Sbjct: 171 DETVGPVPHGAGD---LSYIQFSSGSTSEPKGIVATQASLSANCKAIIQEGLQVRAGDRA 227
Query: 660 ALCLDPYCGLGFALWCLSSIYSGHHSILIPPSEVEVNPALWLSAVSQYKVRDTFCSYGVM 719
L Y +G + ++ +YS + P++ P WL +S K ++
Sbjct: 228 VSWLPLYHDMGLVGFFIAPMYSQLSIDFLSPTDFARRPGTWLKLISANKGTLSYSPSFGY 287
Query: 720 ELCTKGLGSSVNQLKSKGINLACVRTCVVVAEERPRINLTNSFSKLFSALGLSPRAVSTS 779
ELC V + + + ++L+ R + + R + + FS+ F+A G A S
Sbjct: 288 ELC-------VRRFRGEPLDLSSWR-AAGIGGDMVRADALDQFSETFAASGFRKEAFVAS 339
Query: 780 FGCRVNIAICLQGASSPEPSTVYVDLRALRNDRVSLVERGSPHS--------LCLMESGK 831
+G + A S P +++ + R+ ER P S + GK
Sbjct: 340 YGLAESTL-----AVSFAPLNTGLNIDRVDVARMQASERAVPASDLTREGADRAFVSCGK 394
Query: 832 LLPGVKVITANPETKGQCGDSHLGEIWVQSPHNASGYF 869
L ++ +PE + G +G I+++S ASGYF
Sbjct: 395 PLESTELKIVDPE-GSELGLRQVGRIFIRSASLASGYF 431
>UniRef50_Q666G1 Cluster: Possible high molecular weight siderophore
biosynthesis protein; n=20; Yersinia|Rep: Possible high
molecular weight siderophore biosynthesis protein -
Yersinia pseudotuberculosis
Length = 3886
Score = 57.6 bits (133), Expect = 2e-06
Identities = 56/225 (24%), Positives = 103/225 (45%), Gaps = 22/225 (9%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPH 544
L+ +L +R+ L E+G V HV + P G D I A ++GA V I
Sbjct: 3316 LSYQQLEHAVQRLAQYLHEQG-VRESAHVGVALPRGCDQIIAVLAIQWLGAAYVPINVEW 3374
Query: 545 PQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKK 604
P + + T + D+ ++ +++ L E +VL ++ P++ D+ P
Sbjct: 3375 PACRRSQVIT---LADIH---FLIGDRT----LGWPEEVDVLSVESDPVS---DERPTP- 3420
Query: 605 LPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIALCLD 664
R +A+ LAYL F+ +TG+ G+ +SH A + S+ ++ P + AL L
Sbjct: 3421 -----RVVSADSLAYLIFTSGSTGVPKGVAVSHGAAVNTIESVNRQHQINP-QDTALALS 3474
Query: 665 PYCGLGFALWCLSSIYSGHHSILIPPSEVEVNPALWLSAVSQYKV 709
++W + + S +++ P + + A+WLS V Q++V
Sbjct: 3475 ALY-FDLSVWDVFGVLSAGARLVLIPQQAQREAAIWLSLVQQHQV 3518
Score = 50.4 bits (115), Expect = 3e-04
Identities = 73/398 (18%), Positives = 150/398 (37%), Gaps = 17/398 (4%)
Query: 515 LIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVI 574
L+ P G + +F C+ G V + + L ++ T+ I+ S+ + + S+
Sbjct: 67 LLIPGGSPFVISFIACIIRGVSAVPVHLTNHFKLGRSIDTLSHILADSQCEYIFTLSSLS 126
Query: 575 KLLRSK--EASNVLDSKAWPMTLDTDDMPKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAG 632
++ + + ++ + +T + P KK P+ + YL +S +T
Sbjct: 127 DEIKKQGWQRTHQIIFVDQQLTDSSRYFPTKKNYDALYYPS-HLPVYLQYSSGSTAKPKA 185
Query: 633 I-KMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIPPS 691
+ H ++ + P A L Y LG L + SG +P
Sbjct: 186 VCNYDHNMRVQHHILLESHLDCQPKIITANWLPFYHDLGMFSGLLLPLLSGGCCNFMPSV 245
Query: 692 EVEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVVAE 751
P WL ++ Y+ +LCT + V + + ++L+ ++ + AE
Sbjct: 246 HFIAEPFRWLKMINDYQANSGAAPDFAWDLCT----TMVTDEQIRQLDLSSIKMAMNGAE 301
Query: 752 ERPRINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPSTVYVDLRALRND 811
+ N F+ F++ G + + +G + + + AL
Sbjct: 302 PIRPETMAN-FAAHFASTGFDAHSFTPGYGLAEATLTVSHKPIDTDYCCLAFNPMALAAG 360
Query: 812 RVSLVERGSPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNASGYFTI 871
+ L P L+ SG ++ ++ +P+T ++ +GE+WV+ A GY+
Sbjct: 361 KAIL----DPQGRRLISSGHVVRAWQLQIVDPQTCQPLPEASIGEVWVRGDSVAGGYW-- 414
Query: 872 YGDESDYADHFSAQLVTGNTGEVYARTGYLGFLRRTEI 909
+ + + GN+ Y RTG L F+ + E+
Sbjct: 415 --QQPELTKATFHNTLAGNSHHDYLRTGDLAFVYQGEL 450
Score = 45.6 bits (103), Expect = 0.007
Identities = 50/219 (22%), Positives = 89/219 (40%), Gaps = 15/219 (6%)
Query: 24 LDFKRETGLWHAVLASVLNGMHVIFIPYALMKVSPASWMHMITKHRASIAIVKSRDLHWG 83
L F + G++ +L +L+G F+P P W+ MI ++A+ + D W
Sbjct: 217 LPFYHDLGMFSGLLLPLLSGGCCNFMPSVHFIAEPFRWLKMINDYQANSG--AAPDFAWD 274
Query: 84 LLAT----RDHKEISLSSLRMLLVADGANPWSLSSCDQFLSVFQSKGVRGDAICPCACSS 139
L T +++ LSS++M + +GA P + F + F S G + P +
Sbjct: 275 LCTTMVTDEQIRQLDLSSIKMAM--NGAEPIRPETMANFAAHFASTGFDAHSFTPGYGLA 332
Query: 140 ESMTVCIXXXXXXXXXXXXXVLSMSGLSYGVVRVDAENSLTSLTLQDCGQVMPSCVIVVV 199
E+ T+ + M+ L+ G +D + L G V+ + + +V
Sbjct: 333 EA-TLTVSHKPIDTDYCCLAFNPMA-LAAGKAILDPQGR----RLISSGHVVRAWQLQIV 386
Query: 200 KMEGPAYLCKTDEVGEICVLSGATGSGYWGLPGLTNTVF 238
+ L + +GE+ V + GYW P LT F
Sbjct: 387 DPQTCQPLPEA-SIGEVWVRGDSVAGGYWQQPELTKATF 424
>UniRef50_A0UXD2 Cluster: Amino acid adenylation domain; n=1;
Clostridium cellulolyticum H10|Rep: Amino acid
adenylation domain - Clostridium cellulolyticum H10
Length = 4196
Score = 57.6 bits (133), Expect = 2e-06
Identities = 46/163 (28%), Positives = 79/163 (48%), Gaps = 15/163 (9%)
Query: 483 KVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRP 542
+++T EL+ A I N++L+K + N D V L+F G D+I G L G V + P
Sbjct: 2387 RLVTYGELNDSANNIANIILKKSKSN--DRVTLLFEHGADMIIGILGVLKTGRSYVPLDP 2444
Query: 543 PHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDM-- 600
+P+ V + D S A ++++N +K ++E ++L+ K + + +D D+
Sbjct: 2445 AYPEE-----RLVDIFKD-SGAEILVTNDKNLKY--AEELVHILNRKVYLINIDKVDLIS 2496
Query: 601 PKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSL 643
P I A E AY+ ++ TTG G+ SH + L
Sbjct: 2497 PANNPKI---AIEPEQTAYILYTSGTTGKPKGVMQSHKNIMEL 2536
>UniRef50_Q47NS0 Cluster: Amino acid adenylation; n=1; Thermobifida
fusca YX|Rep: Amino acid adenylation - Thermobifida
fusca (strain YX)
Length = 1074
Score = 57.2 bits (132), Expect = 2e-06
Identities = 49/176 (27%), Positives = 79/176 (44%), Gaps = 12/176 (6%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPH 544
LT E+H +A R+ LL E+G V GD VA+ P DL+ A G L GA + + H
Sbjct: 479 LTYREVHDRAGRLAALLAERG-VAPGDVVAVALPRSADLVIALLGVLRAGAAYLPLDVDH 537
Query: 545 PQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKK 604
P + +V+ ++A V++ Q + L + V+ A T D
Sbjct: 538 PP------ARLAAMVERARAGTVVTCQGALPRLGDRLPGTVVVDDA-----ATRDRLAGL 586
Query: 605 LPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIA 660
P+ R + LAY F+ +TG G+ ++H A+ + + M+ L P +A
Sbjct: 587 EPLPTRDVHPDQLAYTIFTSGSTGEPKGVGVAHRAIANRLQWMQHTYRLTPEDRVA 642
>UniRef50_Q6Q883 Cluster: SirP; n=2; Ascomycota|Rep: SirP -
Leptosphaeria maculans (Blackleg fungus)
Length = 2176
Score = 57.2 bits (132), Expect = 2e-06
Identities = 42/158 (26%), Positives = 74/158 (46%), Gaps = 12/158 (7%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGA--VPVTIRP 542
+T ELH + + N L + G + +G + +I L++I A G + GA VP+
Sbjct: 71 ITYGELHYASNHLANHLSQIG-IQSGQKIVIISNRSLEMIVALLGIMKSGACVVPIDFET 129
Query: 543 PHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPK 602
+ TTL T + +S + + NQ +I L + + +VLD++ D P
Sbjct: 130 WSQDRIQTTLETTQCRYAISTKCIEIPNQELI-LFQEGDLQHVLDNRR--------DQPA 180
Query: 603 KKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAV 640
++ P+A+ LAY F+ TT G+ + H+A+
Sbjct: 181 SFSTRGFQLPSADDLAYTIFTSGTTSKPKGVMVPHSAI 218
>UniRef50_A2QYX4 Cluster: Contig An12c0080, complete genome; n=1;
Aspergillus niger|Rep: Contig An12c0080, complete genome
- Aspergillus niger
Length = 5054
Score = 56.4 bits (130), Expect = 4e-06
Identities = 48/174 (27%), Positives = 80/174 (45%), Gaps = 14/174 (8%)
Query: 486 TCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPHP 545
T EL K + I + +L G V++GD VAL A G + VT+ P HP
Sbjct: 2487 TYEELEKCSSLIASQVLVHG-VSSGDFVALYHEKSRWAAAAILAVFKAGGILVTLDPAHP 2545
Query: 546 QNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKKL 605
++ ++ I+D ++ LVL++QS++ R E ++ A + MP +
Sbjct: 2546 KD------RIKDILDQARPRLVLTSQSLLDEARELETPVMVVQFA-----ASQPMPGECF 2594
Query: 606 PIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHI 659
P+ +PT AY F+ +TG GI + H + + S+ AC L P+ +
Sbjct: 2595 PLPTVSPT--QAAYAPFTSGSTGRPKGIPLEHRGLAASTASVARACLLRPASRV 2646
Score = 44.4 bits (100), Expect = 0.017
Identities = 52/218 (23%), Positives = 88/218 (40%), Gaps = 18/218 (8%)
Query: 484 VLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPP 543
+ T AE+ + R+ L+ G V +G + + P + A G L GA +
Sbjct: 4034 IFTFAEVDDLSSRLAARLIRMG-VTSGHIIPIYSPKSRWTVIAILGVLKTGAAFTLLETS 4092
Query: 544 HPQNLHTTLPTVRMIVDVSKATLVLSNQS-VIKLLRSKEASNVLDSKAWPMTLDTDDMPK 602
HP +R+I + KA ++++ S + VLDS ++D +P
Sbjct: 4093 HPT------ARLRVICNEIKADIIIAPASHAVPAATLAPILVVLDSITSMSPQESDLLPA 4146
Query: 603 KKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIALC 662
+P P AE LAYL F+ +TG G+ ++H + S M + + +
Sbjct: 4147 VGMP-----PAAEALAYLIFTSGSTGNPKGVMVTHQNLCSNASIMTTSVNMTSDSRVLHF 4201
Query: 663 LDPYCGLGFALW-CLSSIYSGHHSILIPPSEVEVNPAL 699
LW ++++G + LI PSE E L
Sbjct: 4202 ASH--AFDACLWEIFGALFAG--ACLIIPSESETKEDL 4235
>UniRef50_O94116 Cluster: Peptide synthetase; n=1; Aureobasidium
pullulans|Rep: Peptide synthetase - Aureobasidium
pullulans
Length = 4912
Score = 56.0 bits (129), Expect = 5e-06
Identities = 51/209 (24%), Positives = 100/209 (47%), Gaps = 19/209 (9%)
Query: 445 DSDAARKYQFISQILRWRAQSTSDHVIFTLLNA--KGAVS-KVLTCAELHKKAERIGNLL 501
D A ++++ ++ +S SD + ++A G +S + T +L ++A +I +LL
Sbjct: 2704 DPIIATDFKYLHEMTEASVKSYSDRIAMEFVDALEDGQISSRHWTYRQLDEEANKIAHLL 2763
Query: 502 LEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVR--MIV 559
+++G V GD +A F + AFYG L G I P T P R I+
Sbjct: 2764 IDRG-VKPGDIIATSFDKCPEASFAFYGILKAGCAFCAIDP--------TAPAARKAFIL 2814
Query: 560 DVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKKLPIMYRAPTAEMLAY 619
+ S A ++L++ S+ LR +++D + + +++ +P+ AP++ ++Y
Sbjct: 2815 EDSNARVLLTSDSIRSELRELTQCDIIDLINFE---NKNELSTSSVPVSGLAPSS--VSY 2869
Query: 620 LDFSVSTTGMLAGIKMSHAAVTSLCRSMK 648
+ ++ TTG G +++H L S K
Sbjct: 2870 VLYTSGTTGTPKGCEITHDNAVQLVMSFK 2898
>UniRef50_Q9LCU0 Cluster: PstD; n=2; Mycobacterium avium|Rep: PstD -
Mycobacterium avium
Length = 1400
Score = 55.6 bits (128), Expect = 7e-06
Identities = 53/210 (25%), Positives = 94/210 (44%), Gaps = 34/210 (16%)
Query: 486 TCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPHP 545
T EL++ R+ +LL + G G VA++ P + + A L GA V I P P
Sbjct: 464 TYRELYESTNRLAHLLSDHG-AGPGQRVAVVIPRSAEAVVAILAVLKTGAAYVPIDPGVP 522
Query: 546 QNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDM----- 600
++ VL++ + + + + E + LD P+ +D DD
Sbjct: 523 ---------------AARLQFVLADSAPVAAVTTAEVRDRLDGFELPV-IDVDDPALAGE 566
Query: 601 PKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIA 660
P LP+ P A+ +AYL ++ TTG+ G+ +SH VT L +S+ +++ H +
Sbjct: 567 PSTGLPL----PAADSIAYLIYTSGTTGVPKGVAVSHRNVTQLLQSIDGLGQVWSQCH-S 621
Query: 661 LCLDPYCGLGFALW-CLSSIYSGHHSILIP 689
L D F++W ++ G +++P
Sbjct: 622 LAFD------FSVWEIFGALLHGGRLVIVP 645
>UniRef50_Q197G2 Cluster: Nonribosomal peptide synthetase; n=2;
Streptomyces|Rep: Nonribosomal peptide synthetase -
Streptomyces levoris
Length = 3428
Score = 55.6 bits (128), Expect = 7e-06
Identities = 60/297 (20%), Positives = 115/297 (38%), Gaps = 9/297 (3%)
Query: 486 TCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPHP 545
T LH+ A R+ + L E+ + GDH+ + + AF+ ++ G V V + PH
Sbjct: 58 TYGALHEDALRLSHWLTERAGLRAGDHLIFQLNNSHEYLRAFWAAVHAGIVVVPLNVPHV 117
Query: 546 QNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKKL 605
+ ++ + +++ ++ L + + V + DT ++P
Sbjct: 118 IDRGNLEGVSNVLSTLGSGHVLIGSRPADAYLPAVTGAGVPRDAVLALPRDT-ELPDPGS 176
Query: 606 PIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIALCLDP 665
A + A + F+ +TG G +HAA+ L R + + I L P
Sbjct: 177 STATAAAEPDGAAVIFFTSGSTGAPKGAVQTHAAI--LAREAGVMQLDGGATDIQLNWMP 234
Query: 666 Y-CGLGFALWCLSSIYSGHHSILIPPSEVEVNPALWLSAVSQYKVRDTFCSYGVMELCTK 724
G + L + + + P + +P +WL + +Y+V T+ L
Sbjct: 235 LEHAAGILMSHLRGVCRLGEQVQVAPGHILADPLVWLDLIDKYRVNYTWAPQFAYSL--- 291
Query: 725 GLGSSVNQLKSKGINLACVRTCVVVAEERPRINLTNSFSKLFSALGLSPRAVSTSFG 781
LG+ V K +L+C+R + E + S+L + GL P + +G
Sbjct: 292 -LGNLVPTRKDASWDLSCLRQSINAGEMLNARAVAQLTSQL-AEFGLRPDVIVPVWG 346
>UniRef50_A4D936 Cluster: CrpD; n=2; Nostocaceae|Rep: CrpD - Nostoc
sp. ATCC 53789
Length = 3343
Score = 55.6 bits (128), Expect = 7e-06
Identities = 75/316 (23%), Positives = 133/316 (42%), Gaps = 15/316 (4%)
Query: 469 HVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFY 528
H T +N+ G+ +V + A+L + A+RI + G + D V L D I AF+
Sbjct: 1883 HKGITYINSDGS-EQVQSYAQLLEDAQRILGGFRKLG-IKPQDKVILQLKENKDFISAFW 1940
Query: 529 GCLYVGAVPV-TIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLD 587
GC+ G +PV + P + L ++ + + L+L+++ + L+ K + N+ D
Sbjct: 1941 GCVLGGFIPVPVVIPVSYDQPNVNLNKLQNSWQMLERPLILTDKKSLSELK-KWSQNLND 1999
Query: 588 SKAWPMTLDTDDMPKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSM 647
T+++ + K Y E LA + +TGM +++SH + L R++
Sbjct: 2000 DNFKLETIES--LQKFSTDKDYYNAQPEDLALFMLTSGSTGMSKVVQLSH--LNLLSRTI 2055
Query: 648 -KIACELYPSRHIALCLDPYCGL-GFALWCLSSIYSGHHSILIPPSEVEVNPALWLSAVS 705
I + I L P + G + + IY G I V P WL +
Sbjct: 2056 GSIQMNNFTPEDITLNWMPLDHVAGLIYFHIRDIYLGCKQIHATSQLVIEKPLRWLDWID 2115
Query: 706 QYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVVAEERPRINLTNSFSKL 765
+ V TF L + V +++ + NL+ +R + AE+ F KL
Sbjct: 2116 TFGVTVTFAPNFAYSL----INDFVQEIEKQNWNLSSIRLMLNGAEQIVAAT-ARRFLKL 2170
Query: 766 FSALGLSPRAVSTSFG 781
+ GL A++ S+G
Sbjct: 2171 LAPFGLPGDAMTPSWG 2186
>UniRef50_Q04747 Cluster: Surfactin synthetase subunit 2; n=9;
Bacillus|Rep: Surfactin synthetase subunit 2 - Bacillus
subtilis
Length = 3587
Score = 55.6 bits (128), Expect = 7e-06
Identities = 44/159 (27%), Positives = 73/159 (45%), Gaps = 10/159 (6%)
Query: 486 TCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPHP 545
T EL+ KA R+ +L++ G ++ D V ++ P L++ A G L GA V I P +P
Sbjct: 2572 TYGELNAKANRLARILMDCG-ISPDDRVGVLTKPSLEMSAAVLGVLKAGAAFVPIDPDYP 2630
Query: 546 QNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKKL 605
+ I+ S A L+L + + +LD ++L D+ +
Sbjct: 2631 DQ------RIEYILQDSGAKLLLKQEGISVPDSYTGDVILLDGSRTILSLPLDENDEGNP 2684
Query: 606 PIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLC 644
A TAE LAY+ ++ TTG G+ + A+ +LC
Sbjct: 2685 ET---AVTAENLAYMIYTSGTTGQPKGVMVEDHALVNLC 2720
>UniRef50_Q70LM5 Cluster: Linear gramicidin synthetase subunit C
[Includes: ATP-dependent valine adenylase (ValA) (Valine
activase); ATP-dependent D-valine adenylase (D-ValA)
(D-valine activase); Valine racemase [ATP-hydrolyzing]
(EC 5.1.1.-); ATP-dependent tryptophan adenylase (TrpA)
(Tryptophan activase); ATP-dependent D-leucine adenylase
(D-LeuA) (D-leucine activase); Leucine racemase
[ATP-hydrolyzing] (EC 5.1.1.-); ATP- dependent
tryptophan/phenylalanine/tyrosine adenylase
(Trp/Phe/TyrA) (Tryptophan/phenylalanine/tyrosine
activase); ATP-dependent D-leucine adenylase (D-LeuA)
(D-leucine activase); Leucine racemase [ATP- hydrolyzing]
(EC 5.1.1.-)]; n=11; cellular organisms|Rep: Linear
gramicidin synthetase subunit C [Includes: ATP-dependent
valine adenylase (ValA) (Valine activase); ATP-dependent
D-valine adenylase (D-ValA) (D-valine activase); Valine
racemase [ATP-hydrolyzing] (EC 5.1.1.-); ATP-dependent
tryptophan adenylase (TrpA) (Tryptophan activase);
ATP-dependent D-leucine adenylase (D-LeuA) (D-leucine
activase); Leucine racemase [ATP-hydrolyzing] (EC
5.1.1.-); ATP- dependent
tryptophan/phenylalanine/tyrosine adenylase
(Trp/Phe/TyrA) (Tryptophan/phenylalanine/tyrosine
activase); ATP-dependent D-leucine adenylase (D-LeuA)
(D-leucine activase); Leucine racemase [ATP- hydrolyzing]
(EC 5.1.1.-)] - Brevibacillus parabrevis
Length = 7756
Score = 55.6 bits (128), Expect = 7e-06
Identities = 43/175 (24%), Positives = 85/175 (48%), Gaps = 15/175 (8%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPH 544
LT A+L+++A ++ + LL + V V + ++I +G + GA V I P
Sbjct: 3089 LTYADLNQRANQLAHRLLAQ-EVKPDTLVGICVERSPEMIIGIFGVMKAGAAYVPIDPAL 3147
Query: 545 PQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKK 604
PQ + +V+ S+A+++L+ QS+ +LL +A + LD D + +
Sbjct: 3148 PQE------RIAYMVEDSQASILLTQQSLAELLPKTQARVIC--------LDGDSLANEP 3193
Query: 605 LPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHI 659
+ T + LAY+ ++ +TG+ G+ + H +V +L ++ A + PS +
Sbjct: 3194 VANPASEVTEQNLAYVMYTSGSTGLPKGVMVEHHSVVNLAHALIEAFRIQPSSRV 3248
Score = 53.2 bits (122), Expect = 4e-05
Identities = 40/159 (25%), Positives = 80/159 (50%), Gaps = 15/159 (9%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPH 544
LT AEL+++A ++ + LL +G V + V + ++I AF G + GA V + P H
Sbjct: 5668 LTYAELNERANQLAHRLLAEG-VKPDELVGICVERSPEMIVAFLGVMKAGAAYVPLDPAH 5726
Query: 545 PQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKK 604
PQ + +++ S+A+++L+ S+ L + S + LD+D++ +
Sbjct: 5727 PQE------RIAYMIEDSQASVLLTQASLTDRLPA--------SSRQVICLDSDELANEP 5772
Query: 605 LPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSL 643
+ + LAY+ ++ +TG+ G+ + H +V +L
Sbjct: 5773 VTNAETSVGEHNLAYVIYTSGSTGLPKGVMIEHRSVINL 5811
Score = 49.6 bits (113), Expect = 4e-04
Identities = 37/159 (23%), Positives = 78/159 (49%), Gaps = 13/159 (8%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPH 544
+T AEL KA ++ N L ++G ++ V + +D++ A G L G V + P +
Sbjct: 4138 ITYAELDAKANQVANYLHKQGIISE-TLVGVCLDRSIDMLVAQLGILKAGGAYVPMDPAY 4196
Query: 545 PQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKK 604
PQ + ++ ++ +VL+ + ++ L A+ + + W + + D+
Sbjct: 4197 PQE------RLAFMMQDAEMPVVLTQEHLLAQLPEARATFLCLDRDWSLIAEESDVA--- 4247
Query: 605 LPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSL 643
P++ A + LAY+ ++ +TG G+++ HAA+ +L
Sbjct: 4248 -PVI--ATNRDNLAYVIYTSGSTGTPKGVEIEHAALLNL 4283
Score = 48.4 bits (110), Expect = 0.001
Identities = 51/238 (21%), Positives = 100/238 (42%), Gaps = 19/238 (7%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPH 544
LT AEL KA ++ N L ++G V G V L LD++ L G V + P +
Sbjct: 1560 LTYAELDTKANQLANYLQKQG-VEAGTLVGLCVDRSLDMLVGLLAILKAGGAYVPLDPAY 1618
Query: 545 PQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNV-LDSKAWPMTLDTDDMPKK 603
P+ M+ D + +++L+ + + K + ++ V LD A T ++ P
Sbjct: 1619 PEE-----RLAFMLAD-ANVSILLTQKHLGKQWKGRKRRTVYLDRDAKKWTAESPLAPAV 1672
Query: 604 KLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIALCL 663
T + LAY+ ++ +TG G+ ++H + L ++ +
Sbjct: 1673 D-------ATKDSLAYVIYTSGSTGTPKGVLVAHRGIVRLVKNTNYVTITEEDVFLQAST 1725
Query: 664 DPYCGLGFALWCLSSIYSGHHSILIPPSEVEVNPALWLSAVSQYKVRDTFCSYGVMEL 721
+ F +W ++ +G +L+PP ++ A+ Q+KV + + G+ +
Sbjct: 1726 VSFDAATFEIW--GALLNGAKLVLMPPDLPSLDEL--GEAIVQHKVTTLWLTAGLFSI 1779
Score = 44.0 bits (99), Expect = 0.022
Identities = 54/245 (22%), Positives = 102/245 (41%), Gaps = 32/245 (13%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPH 544
LT AEL +A ++ N L ++G V G V L LD++ L G V I P +
Sbjct: 494 LTYAELEARANQLANYLQKQG-VEAGTLVGLCVDRSLDMLIGLLAILKAGGAYVPIDPAY 552
Query: 545 PQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVL---DSKAW----PMTLDT 597
P+ M+ D +K +++L+ + + K + ++ V D+K W P+ D
Sbjct: 553 PEE-----RLAFMLAD-AKISILLTQKHLGKQWKGRKRRTVYLDRDAKKWAEESPLAPDV 606
Query: 598 DDMPKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSR 657
D T + LAY+ ++ +TG G+ H V L + + + +
Sbjct: 607 D-------------TTKDSLAYVIYTSGSTGTPKGVLAVHRGVVRLGQKTRTTSPISEAD 653
Query: 658 -HIALCLDPYCGLGFALWCLSSIYSGHHSILIPPSEVEVNPALWLSAVSQYKVRDTFCSY 716
+ + F +W ++ +G +L+PP ++ A+ Q+KV + +
Sbjct: 654 VFLQASTVSFDAATFEIW--GALLNGAKLVLMPPDLPSLDEL--GEAIVQHKVTTLWLTA 709
Query: 717 GVMEL 721
G+ +
Sbjct: 710 GLFSI 714
Score = 41.9 bits (94), Expect = 0.090
Identities = 45/215 (20%), Positives = 90/215 (41%), Gaps = 19/215 (8%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPH 544
LT A+L KA ++ N L ++G + V + ++I G L G V + P +
Sbjct: 6722 LTYAQLDAKANQLANYLQQQG-ITPETLVGICVERSSEMIVGQLGILKAGGAFVPMDPAY 6780
Query: 545 PQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKK 604
PQ M+ D VL+ + +++ L + +A+ + W + + +
Sbjct: 6781 PQER-----LAFMMADTGMP-FVLTQERLLETLPAGDAAFICLDADWEVIAEESTQAPEL 6834
Query: 605 LPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIALCLD 664
A T + LAY+ ++ +TG G+++ H A+ +L + A + P +
Sbjct: 6835 ------AVTTDQLAYVIYTSGSTGTPKGVEIEHRALLNLIYWHQHAYTITPDDRAS---- 6884
Query: 665 PYCGLGF--ALWCLSSIYSGHHSILIPPSEVEVNP 697
G F A+W + + ++ +P E+ + P
Sbjct: 6885 QIAGTAFDAAVWEIWPYMTAGATLYLPQEEIRLIP 6919
>UniRef50_Q6D738 Cluster: Non-ribosomal peptide synthetase; n=3;
Bacteria|Rep: Non-ribosomal peptide synthetase - Erwinia
carotovora subsp. atroseptica (Pectobacterium
atrosepticum)
Length = 7523
Score = 55.2 bits (127), Expect = 9e-06
Identities = 49/205 (23%), Positives = 92/205 (44%), Gaps = 15/205 (7%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPH 544
L+ AEL+++A ++ + LL G + D VAL L+++ G L GA V + P +
Sbjct: 508 LSYAELNRRANQLAHRLLTLG-IKPDDRVALCVERSLEMVVGLMGILKSGAAYVPLDPTY 566
Query: 545 PQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKK 604
P + ++D +K +L+ + I + + + +LD+ ++ T + +
Sbjct: 567 PAE------RLAYMIDDAKPVALLTQANQIAIQTADIPAIMLDTDSFD-AYATSNPDAQA 619
Query: 605 LPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIALCLD 664
L + T+ LAY+ ++ +TG G+ ++H V +L +K S IAL
Sbjct: 620 LGV-----TSTHLAYVIYTSGSTGKPKGVMVTHRNVLNLASGLKTLLAFEHSNRIALNAS 674
Query: 665 PYCGLGFALWCLSSIYSGHHSILIP 689
W I SGH +++P
Sbjct: 675 IVFDASVQNWI--QILSGHTLVIVP 697
Score = 53.2 bits (122), Expect = 4e-05
Identities = 54/206 (26%), Positives = 92/206 (44%), Gaps = 19/206 (9%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPH 544
LT EL+++A ++ + L+ G V D VAL L+++ G L GA V + P +
Sbjct: 4800 LTYRELNRRANQLAHHLIALG-VQPDDRVALCVERSLEMMVGLLGILKAGAAYVPMDPAY 4858
Query: 545 PQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKK 604
P + I+D + +L+ + + L S + +LD+ A DT+
Sbjct: 4859 PAE------RLAYILDDAAPVALLTQSAQVAQLNSTLPTVLLDTPAAAACPDTN------ 4906
Query: 605 LPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACEL-YPSRHIALCL 663
P++ A LAY+ ++ +TG G+ ++H V +L + L +PSR IAL
Sbjct: 4907 -PVVQGLHAAH-LAYVIYTSGSTGRPKGVMVAHRNVINLATGLHTLLALDHPSR-IALNA 4963
Query: 664 DPYCGLGFALWCLSSIYSGHHSILIP 689
W + SGH +L+P
Sbjct: 4964 SIVFDASVKNWI--QLLSGHTLVLVP 4987
Score = 52.8 bits (121), Expect = 5e-05
Identities = 40/164 (24%), Positives = 76/164 (46%), Gaps = 10/164 (6%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPH 544
L+ EL+++A R+ + L+ G V + VA+ GLD++ G L G V + P +
Sbjct: 6933 LSYDELNRRANRLAHHLISFG-VRPDERVAICVERGLDMVVGLLGILKAGGAYVPLDPTY 6991
Query: 545 PQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKK 604
P + +R ++D +K ++S + + ++ +LD T D+ P
Sbjct: 6992 P------VERLRYMLDDAKPVALISQSAHLGIMNGSLPVILLDDGE---TRPFDNEPDTP 7042
Query: 605 LPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMK 648
L + T LAY+ ++ +TG G+ + HA + + SM+
Sbjct: 7043 LDARKQGLTPRHLAYVIYTSGSTGKPKGVMVEHANMVNFLCSMR 7086
Score = 46.8 bits (106), Expect = 0.003
Identities = 42/159 (26%), Positives = 74/159 (46%), Gaps = 10/159 (6%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPH 544
L+ +L+++A R+ + LL G V D +A+ GL++I G L GA V + P +
Sbjct: 3724 LSYDQLNRRANRLAHHLLTLG-VQPDDRIAICVERGLEMIVGLLGILKAGAAYVPLDPSY 3782
Query: 545 PQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKK 604
P + T M+ D + L L+ +++ LL S LD+ P + D+ P
Sbjct: 3783 PVDRLTY-----MLEDAAPVAL-LTQTALVTLLDSPLPVIELDNL--PAAI-ADETPDSN 3833
Query: 605 LPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSL 643
T LAY+ ++ +TG G+ + H ++ +L
Sbjct: 3834 PTPQAFGLTPNHLAYVIYTSGSTGKPKGVMVEHRSLCNL 3872
Score = 45.6 bits (103), Expect = 0.007
Identities = 39/158 (24%), Positives = 72/158 (45%), Gaps = 14/158 (8%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPH 544
+T EL+++A R+ + LL G V D VA+ D++ G L GA V + P +
Sbjct: 1585 VTYDELNRRANRLAHHLLSFG-VKPDDRVAICLERSPDMVVGLLGILKAGAAYVPLDPSY 1643
Query: 545 PQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKK 604
P + ++D + +L++ S+I+ + VLD+ A P D P
Sbjct: 1644 PAE------RLAYMLDDADPVALLTHSSLIESFSHTSPTIVLDNAA-PFDACPDTNP--- 1693
Query: 605 LPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTS 642
+ + A LAY+ ++ +TG G+ + H +++
Sbjct: 1694 ---VIQGLNAAHLAYIIYTSGSTGKPKGVMVEHRGLSN 1728
>UniRef50_Q4ZT75 Cluster: Amino acid adenylation; n=2; Pseudomonas
syringae pv. syringae|Rep: Amino acid adenylation -
Pseudomonas syringae pv. syringae (strain B728a)
Length = 9498
Score = 55.2 bits (127), Expect = 9e-06
Identities = 51/205 (24%), Positives = 87/205 (42%), Gaps = 11/205 (5%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPH 544
L+ +L+++A + LL+ G V + VA+ LD+I G L GA V I P H
Sbjct: 8092 LSYRQLNRRANHVARQLLQLG-VQPDERVAICAERSLDMIVGLLGVLKSGAAYVPIDPAH 8150
Query: 545 PQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKK 604
P + M+ D L+ Q + L +LDS L DD
Sbjct: 8151 PAD-----RMAFMLQDSQPRALL--TQGALSLPVGDTPLMLLDSA--ESLLAADDQAFDA 8201
Query: 605 LPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIALCLD 664
P++ TAE LAY+ ++ +TG G+ + H +V + + + + L+
Sbjct: 8202 NPVV-DGLTAENLAYVIYTSGSTGQSKGVMVEHRSVFNFWNVLTRTTHQHCPTPATVALN 8260
Query: 665 PYCGLGFALWCLSSIYSGHHSILIP 689
++ +S ++SGH ++IP
Sbjct: 8261 AGFFFDMSIKGISQLFSGHKLVIIP 8285
Score = 42.7 bits (96), Expect = 0.051
Identities = 51/225 (22%), Positives = 93/225 (41%), Gaps = 19/225 (8%)
Query: 490 LHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQN-- 547
L+++A R+ + LL +G V D VA++ G +ICA L GA V + P +P
Sbjct: 6999 LNRRANRLAHELLAQG-VRPDDRVAILAERGTQMICAVLAVLKSGAAYVPLDPTYPTERL 7057
Query: 548 ---LHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKK 604
L + P + L + V+ L +++++ D +LD + P
Sbjct: 7058 GYLLTDSAPVALLAQSACLDVLPAHSVPVLTLGADNDSADLADE-----SLDRNPEPAAL 7112
Query: 605 LPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIALCLD 664
+ E LAY+ ++ +TG+ G+ + H V L + A + L
Sbjct: 7113 ------GLSREHLAYVIYTSGSTGLPKGVLVEHGNVARLFDA--TAGQFNFGHEDVWTLF 7164
Query: 665 PYCGLGFALWCLSSIYSGHHSILIPPSEVEVNPALWLSAVSQYKV 709
F++W + ++I PSEV +P + + V + +V
Sbjct: 7165 HSFAFDFSVWEIWGALCYGGKLVIVPSEVARSPDDFYALVCEQQV 7209
Score = 42.3 bits (95), Expect = 0.068
Identities = 48/218 (22%), Positives = 98/218 (44%), Gaps = 17/218 (7%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPH 544
L+ AEL+++A R+ + L+ G + D VA+ G++++ G L GA V + P +
Sbjct: 4869 LSYAELNRQANRVAHHLISLG-IKPDDRVAICVERGVEMLIGVLGVLKAGAAYVPLDPAY 4927
Query: 545 PQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTL-DTDDMPKK 603
P + +++ S + +L+ + V L + + VL + TL + D P
Sbjct: 4928 PAE------RLAYMIEDSTPSALLAQRDVQAHLPTLDLPLVLLDEDQRTTLSERGDNP-- 4979
Query: 604 KLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELY-PSRHIALC 662
+ A LAY+ ++ +TG+ G+ + H + ++ + + L+ P H+ +
Sbjct: 4980 ----VVETLGAHNLAYVIYTSGSTGVPKGVMVEHRGLFAVSAAWEQLYALHAPLNHLQMA 5035
Query: 663 LDPYCGLGFALWCLSSIYSGHHSILIPPSEVEVNPALW 700
+ F+ + S+ G +L P + PAL+
Sbjct: 5036 --GFSFDVFSADLIRSLAFGGTLVLCPRETLMDPPALY 5071
Score = 37.5 bits (83), Expect = 1.9
Identities = 40/165 (24%), Positives = 66/165 (40%), Gaps = 8/165 (4%)
Query: 478 KGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVP 537
+G +LT AEL+++A ++ + L+E G V VA+ G +++ A G L G
Sbjct: 533 RGDSGPLLTYAELNQQANQLAHRLIELG-VEPDTRVAVSLRRGAEMVVALLGILKAGGAY 591
Query: 538 VTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDT 597
V I P P + M+ D S ++ + L S VLD L +
Sbjct: 592 VPIDPDLP-----SARQAYMLEDSSPQAVLTTRDLSDNLPASDHPVLVLDGHDDRAQLAS 646
Query: 598 DDMPKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTS 642
+ P LAY+ ++ +TG G+ H V +
Sbjct: 647 QPTGNPDAKALGLQP--NHLAYVLYTSGSTGTPKGVMNEHLGVVN 689
Score = 35.9 bits (79), Expect = 5.9
Identities = 28/105 (26%), Positives = 47/105 (44%), Gaps = 6/105 (5%)
Query: 441 GYTDDSDAARKYQFISQILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNL 500
G+ D + + I Q++ +A D +G +LT AEL+++A ++ +
Sbjct: 1591 GFNDTAHPYPRDVLIHQLIEQQAAQRPDACA-----VRGDSGPLLTYAELNQQANQLAHR 1645
Query: 501 LLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPHP 545
L+E G V VA+ G +++ A G L G V I P P
Sbjct: 1646 LIELG-VEPDTRVAVSLRRGPEMVVALLGILKAGGAYVPIDPDLP 1689
>UniRef50_Q7N2F7 Cluster: Complete genome; segment 11/17; n=4;
Photorhabdus luminescens subsp. laumondii|Rep: Complete
genome; segment 11/17 - Photorhabdus luminescens subsp.
laumondii
Length = 5457
Score = 54.8 bits (126), Expect = 1e-05
Identities = 55/196 (28%), Positives = 88/196 (44%), Gaps = 15/196 (7%)
Query: 480 AVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVT 539
A K+L+ EL+ +A + + L+E+G V +GDH+AL+ + L+ A L VGAV V
Sbjct: 1380 AGDKMLSYTELNTRANWLAHQLIEQG-VCSGDHIALLLERSIALVVAQLAILKVGAVYVP 1438
Query: 540 IRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDD 599
+ P P L I D S L+ Q+ I + + D DTD
Sbjct: 1439 VDPSMPDERKNWL-----ISDCSARLLLTDTQADIPANLTVPLLRLSDQS------DTDG 1487
Query: 600 MPKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHI 659
++ +AE LAY+ ++ +TG G+ + H AV L + A E+ P +
Sbjct: 1488 REEECFNPDLPRSSAE-LAYIMYTSGSTGTPKGVLVPHRAVVRLVINNDYA-EVGPDDRV 1545
Query: 660 ALCLDP-YCGLGFALW 674
A +P + F +W
Sbjct: 1546 AFTANPAFDASTFEVW 1561
Score = 48.0 bits (109), Expect = 0.001
Identities = 64/286 (22%), Positives = 121/286 (42%), Gaps = 21/286 (7%)
Query: 480 AVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVT 539
A K L+ EL+ A R+ L+E+G + DHVAL+ ++L+ A L GAV V
Sbjct: 3533 AGDKTLSYMELNTCANRLAYQLIEQG-IRPDDHVALLLERSIELVVAQLAILKAGAVYVP 3591
Query: 540 IRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDD 599
+ P P L I D S L+ ++ I + + D K+ D
Sbjct: 3592 VDPSMPDERKHWL-----ISDCSARLLLTDTRADIPANLTIPLLRLSDKKS---ANREQD 3643
Query: 600 MPKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHI 659
LP +AE LAY+ ++ +TG G+ + H A+ L + A + P +
Sbjct: 3644 HVNPNLP----RSSAE-LAYIMYTSGSTGTPKGVLVQHRAMVRLVINNGYA-NIGPEDRV 3697
Query: 660 ALCLDP-YCGLGFALWCLSSIYSGHHSILIPPSEVEVNPALWLSAVSQYKVRDTFCSYGV 718
A +P + F +W + + +G ++I + + + P + + ++++ + + G+
Sbjct: 3698 AFTANPAFDASTFEVW--APLLNGGALVVIDRATL-LTPQELVLTLQEHRITVLWLTIGL 3754
Query: 719 MELCTKGLGSSVNQLKSK--GINLACVRTCVVVAEERPRINLTNSF 762
L + Q+K G ++ ++ V + RP L ++
Sbjct: 3755 FNRLAAELSPILPQIKILIFGGDIPDLKVIAQVLDNRPPQQLLQAY 3800
>UniRef50_A4X8Q7 Cluster: AMP-dependent synthetase and ligase; n=1;
Salinispora tropica CNB-440|Rep: AMP-dependent
synthetase and ligase - Salinispora tropica CNB-440
Length = 536
Score = 54.4 bits (125), Expect = 2e-05
Identities = 69/328 (21%), Positives = 134/328 (40%), Gaps = 17/328 (5%)
Query: 455 ISQILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVA 514
++ +L W A+ SD I G + + EL A L+ +G V GD V
Sbjct: 1 MTHLLSWLAEPRSDRGI-RFARPDGGWDR-WSYDELAGLAHEYAAGLIARG-VRPGDVVT 57
Query: 515 LIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVI 574
++ P G + A +G L GA + P T R ++ A + V+
Sbjct: 58 VVLPSGPAFVGALFGTLLAGATAAPLAPAA-----TFGDPNRYAEHITSALAAARPRLVV 112
Query: 575 KLLRSKEASNVLDSKAWPMTLDTDDMPKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIK 634
+ A L +A T++ +D+ + P+ P LA + F+ TTG + G++
Sbjct: 113 VDAAAGTAVTPLARRAGVPTVEPEDVRAE--PLGAHRPAPARLALVQFTSGTTGTVHGVR 170
Query: 635 MSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIPPSEVE 694
+ + A+ +++ E+ P A L + +G L+ + +G L+ P++
Sbjct: 171 VPYPALEDNIGAIRRWLEMTPEDATASWLPVHHDMGLVGCLLAPVVTGADLWLLSPADFV 230
Query: 695 VNPALWLSAVSQYKVR-DTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVVAEER 753
P +L+ ++ R +G+ + + V + G++ R V+V ER
Sbjct: 231 RQPTRYLACFGRHGARLSAMPGFGLAHVLRR-----VRPEQLAGMDFHHWR-AVIVGAER 284
Query: 754 PRINLTNSFSKLFSALGLSPRAVSTSFG 781
++ + F+ L + GL A+ ++G
Sbjct: 285 VLPDVLDRFAALLAPQGLRRTALLPAYG 312
>UniRef50_Q9HYR8 Cluster: Probable non-ribosomal peptide synthetase;
n=5; Pseudomonas aeruginosa|Rep: Probable non-ribosomal
peptide synthetase - Pseudomonas aeruginosa
Length = 2352
Score = 54.0 bits (124), Expect = 2e-05
Identities = 66/236 (27%), Positives = 104/236 (44%), Gaps = 27/236 (11%)
Query: 474 LLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYV 533
LL A G L+ AEL K + + + L G V T + VAL+ G L+ A G
Sbjct: 464 LLEADGGT---LSYAELDAKVQAVADALRAAG-VRTDERVALLVARGPHLLPAILGVQRA 519
Query: 534 GAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPM 593
G V I P HP L VR++++ A +VL ++ L S + VL + P
Sbjct: 520 GGAYVPINPDHP------LERVRLLLEDCGARVVLVDERAATLGESLGETRVLHLERLPQ 573
Query: 594 TLDTDDMPKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACEL 653
+ T D+P + AP LAY+ ++ +TGM G+ + H +V + M+
Sbjct: 574 S--TGDLPAANV-----APGD--LAYVIYTSGSTGMPKGVMVEHRSVVNRLNWMQ---RR 621
Query: 654 YP--SRHIALCLDPYCGLGFALWCLS-SIYSGHHSILIPPSEVEVNPALWLSAVSQ 706
YP R + L P ++W L ++G L+PP E +P L ++ +
Sbjct: 622 YPIGERDVLLQKTPVT-FDVSVWELFWWSFTGARLSLLPPG-AEKDPREMLRSIQR 675
>UniRef50_Q6DNE7 Cluster: CurF; n=1; Lyngbya majuscula|Rep: CurF -
Lyngbya majuscula
Length = 3195
Score = 54.0 bits (124), Expect = 2e-05
Identities = 51/228 (22%), Positives = 104/228 (45%), Gaps = 18/228 (7%)
Query: 483 KVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRP 542
K LT EL++++ ++G+ L + G V VA++ G + + A G L G + I P
Sbjct: 2570 KSLTYGELYQRSHQLGHGLRKLG-VKPNQLVAVVMEKGWEQVVAVLGILMSGGAYLPIDP 2628
Query: 543 PHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPK 602
PQ L ++ ++ T VL+ + + L E K W ++DT+++ +
Sbjct: 2629 GLPQERQWYL------LEQAQVTQVLTQTHLKQSLGWPEGI-----KCW--SVDTEELAE 2675
Query: 603 KKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPS-RHIAL 661
+ T+E LAY+ ++ +TG+ G+ + H + + ++ PS R +AL
Sbjct: 2676 YDPNPLEPVQTSEDLAYVIYTSGSTGLPKGVMIDHRGAINTILDINQRFKVTPSDRVLAL 2735
Query: 662 CLDPYCGLGFALWCLSSIYSGHHSILIPPSEVEVNPALWLSAVSQYKV 709
+++ + + +I++PP + +PA W + ++V
Sbjct: 2736 AA---LNFDLSVYDIFGVLGAGGAIVMPPPKAAKDPACWRELIIAHEV 2780
>UniRef50_Q50E74 Cluster: Peptide synthetase 1; n=3; Streptomyces
filamentosus|Rep: Peptide synthetase 1 - Streptomyces
filamentosus (Streptomyces roseosporus)
Length = 5830
Score = 54.0 bits (124), Expect = 2e-05
Identities = 56/225 (24%), Positives = 96/225 (42%), Gaps = 16/225 (7%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPH 544
L+ EL+ +A R+ +L+E+G V + P GLDLI A GA V + P +
Sbjct: 4169 LSYKELNARANRLARVLMERG-AGPERFVGVALPRGLDLIVALLAVTKTGAAYVPLDPEY 4227
Query: 545 PQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKK 604
P T M+ D + +V S I L+ + LD +A L
Sbjct: 4228 P-----TDRLAYMVTDANPTAVVTSTDVHIPLIAPRIE---LDDEAIRTELAA---APDT 4276
Query: 605 LPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIALCLD 664
P + P AY+ ++ +TG G+ +SHA V L + + + P H+
Sbjct: 4277 APCVGSGPAHP--AYVIYTSGSTGRPKGVVISHANVVRLFTACSDSFDFGPD-HVWTLFH 4333
Query: 665 PYCGLGFALWCLSSIYSGHHSILIPPSEVEVNPALWLSAVSQYKV 709
Y F++W + +++ P EV +PA +L+ +++ +V
Sbjct: 4334 SY-AFDFSVWEIWGALLHGGRLVVVPFEVTRSPAEFLALLAEQQV 4377
Score = 37.9 bits (84), Expect = 1.5
Identities = 36/165 (21%), Positives = 68/165 (41%), Gaps = 9/165 (5%)
Query: 484 VLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPP 543
VLT A+LH +A R+ L+ V VA+ P +L+ A L GA V +
Sbjct: 1522 VLTYADLHTRANRLARHLITAHGVGPERLVAVALPRSAELLVALLAVLKTGAAYVPLDLT 1581
Query: 544 HPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNV-LDS-KAWPMTLDTDDMP 601
HP +++D + ++L++ + L ++ + LD + + P
Sbjct: 1582 HPAE------RTAVVLDDCRPAVILTDAGAARELPRRDIPQLRLDEPEVHAAIAEQPGGP 1635
Query: 602 KKKLPIMYRAP-TAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCR 645
P + E +AY+ ++ +TG G+ + H ++ R
Sbjct: 1636 VTDRDRTCVTPVSGEHVAYVIYTSGSTGRPKGVAVEHRSLADFVR 1680
Score = 37.5 bits (83), Expect = 1.9
Identities = 22/62 (35%), Positives = 28/62 (45%), Gaps = 1/62 (1%)
Query: 484 VLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPP 543
VLT +LH+ ER L G + T D VAL P + + G GA V + P
Sbjct: 483 VLTYRDLHRSVERAAGRLAGLG-LRTEDVVALALPKSAESVAILLGIQRAGAAYVPLDPT 541
Query: 544 HP 545
HP
Sbjct: 542 HP 543
>UniRef50_A4FD53 Cluster: Putative non-ribosomal peptide synthetase;
n=1; Saccharopolyspora erythraea NRRL 2338|Rep: Putative
non-ribosomal peptide synthetase - Saccharopolyspora
erythraea (strain NRRL 23338)
Length = 2385
Score = 54.0 bits (124), Expect = 2e-05
Identities = 58/226 (25%), Positives = 94/226 (41%), Gaps = 18/226 (7%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPH 544
LT AEL +A + L G + D VAL+ P DL+ A G L GA V I P H
Sbjct: 493 LTYAELDARANSLAQRLTRAG-IGPEDRVALLVPRSADLVVAVLGVLKSGAAYVPIDPDH 551
Query: 545 PQNLHTTLPTVRMIV-DVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKK 603
P + +R ++ D + A LV L + L P + DD P
Sbjct: 552 PAD------RIRFVLGDAAPAALVAGGD----LAELPDVRVPLFHVTAPSS--ADDSPAG 599
Query: 604 KLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIALCL 663
+ P + AY+ ++ +TG G+ +SH V L + + + P +
Sbjct: 600 APQV--APPDVDQPAYVIYTSGSTGTPKGVVVSHRNVVGLFAATESLFQFGP-EDVWTLF 656
Query: 664 DPYCGLGFALWCLSSIYSGHHSILIPPSEVEVNPALWLSAVSQYKV 709
Y F++W L +++ P EV +PA +L +++++V
Sbjct: 657 HSY-AFDFSVWELWGPLLHGGRLVVVPREVTRSPADFLRLLAEHRV 701
>UniRef50_A0QHN3 Cluster: Syringomycin synthetase; n=3; Mycobacterium
avium|Rep: Syringomycin synthetase - Mycobacterium avium
(strain 104)
Length = 6212
Score = 54.0 bits (124), Expect = 2e-05
Identities = 54/217 (24%), Positives = 91/217 (41%), Gaps = 27/217 (12%)
Query: 486 TCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPHP 545
T EL A R+ +LL+ G GD VAL+ + + A G L GA + I P
Sbjct: 5217 TYRELDSSANRLAHLLIHHG-AGPGDCVALLLERSAEAVAAILGVLKAGAAYLPIDP--- 5272
Query: 546 QNLHTTLPTVR---MIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPK 602
+LP+ R M+ D + A ++ S + +L + +D DD
Sbjct: 5273 -----SLPSARIEFMLTDAAPAAVLTSTEFHCRLQEYDQT-----------VIDVDDPSI 5316
Query: 603 KKLPIMYR-APTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIA-CELYPSRHIA 660
++ P+ AP + +AYL ++ TTG+ G+ ++H T L S+ A P +
Sbjct: 5317 REQPVTAPPAPAPDNIAYLIYTSGTTGVPKGVAVTHRNATQLFASLGAAGLPAAPGKVWG 5376
Query: 661 LCLDPYCGLGFALWCLSSIYSGHHSILIPPSEVEVNP 697
C F++W + +L+ P +V +P
Sbjct: 5377 QCHS--LAFDFSVWEIFGALLNGGRVLVVPDDVVRSP 5411
Score = 44.4 bits (100), Expect = 0.017
Identities = 50/223 (22%), Positives = 92/223 (41%), Gaps = 27/223 (12%)
Query: 480 AVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVT 539
A + +T L + A ++ + L+ G G VA++ + + A G L GA +
Sbjct: 4147 ANGRSVTYRRLEEHANQLAHQLIRYG-AGPGRCVAVLLERSAEAVAAILGVLKAGAAYLP 4205
Query: 540 IRPPHPQNLHTTLPTVR---MIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLD 596
I P +LP+ R M+ D + A ++ S + +L + +D
Sbjct: 4206 IDP--------SLPSARIEFMLTDAAPAAVLTSTEFHCRLQEYDQT-----------VID 4246
Query: 597 TDDMPKKKLPIMYR-APTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIA-CELY 654
DD ++ P+ AP + +AYL ++ TTG+ G+ ++H T L S+ A
Sbjct: 4247 VDDPSIREQPVTAPPAPAPDNIAYLIYTSGTTGVPKGVAVTHRNATQLFASLGAAGLPAA 4306
Query: 655 PSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIPPSEVEVNP 697
P + C F++W + +L+ P +V +P
Sbjct: 4307 PGKVWGQCHS--LAFDFSVWEIFGALLNGGRVLVVPDDVVRSP 4347
Score = 44.0 bits (99), Expect = 0.022
Identities = 49/201 (24%), Positives = 84/201 (41%), Gaps = 22/201 (10%)
Query: 477 AKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAV 536
A + + T E+ + A R+ +LL++ G V+ G +V L+ + + A G L GA
Sbjct: 561 AISSADRCWTYREVDETANRLAHLLIQHG-VDRGQYVGLLLDRSAEAVVAILGVLKAGAA 619
Query: 537 PVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLD 596
V + P +P R+ V+ A L + V+ S+ L + +D
Sbjct: 620 YVPMDP--------AVPAARIAFIVADADL----RVVVTDAGSRSRLTGLGAAI----VD 663
Query: 597 TDDMPKKKLPIMYRA---PTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACEL 653
DD P A P A +A++ ++ TTG G+ +SH +T L S+ L
Sbjct: 664 LDDPALADYPATEPAGPGPAAGDIAHVIYTSGTTGEPKGVAVSHRNITQLFASLDTGITL 723
Query: 654 YPSRHIALCLDPYCGLGFALW 674
P + + C F++W
Sbjct: 724 GPDQVWSQCHS--LAFDFSVW 742
>UniRef50_Q0RVL7 Cluster: Fatty-acid--CoA ligase; n=1; Rhodococcus
sp. RHA1|Rep: Fatty-acid--CoA ligase - Rhodococcus sp.
(strain RHA1)
Length = 527
Score = 53.6 bits (123), Expect = 3e-05
Identities = 52/215 (24%), Positives = 96/215 (44%), Gaps = 14/215 (6%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPH 544
L+ A + A++ ++E+G V GD VA+ P GL +++G GA+ V +
Sbjct: 52 LSYARTLELAQKCAVSIVERG-VKPGDRVAIALPNGLHHAVSYFGTQLAGAIAVVV---- 106
Query: 545 PQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMP-KK 603
N + P + ++ S A+LV+S+ S + L S ++V+D P L T+ P
Sbjct: 107 --NTRLSAPEIAHVLSDSGASLVVSDSSFAERLTSD--ADVVD----PQVLLTERPPHAD 158
Query: 604 KLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIALCL 663
P+ + +A+ A L ++ TTG G +HA + +++ EL P+ +
Sbjct: 159 HTPLPGLSRSADDTAQLLYTSGTTGRPKGAAQTHANLLFNAATVREQFELTPNDRTLIVA 218
Query: 664 DPYCGLGFALWCLSSIYSGHHSILIPPSEVEVNPA 698
+ G + + +G +L P + V A
Sbjct: 219 PMFHASGLNSQLIGFLSAGASCVLAPEFKAAVTLA 253
>UniRef50_A7GPR4 Cluster: AMP-dependent synthetase and ligase; n=1;
Bacillus cereus subsp. cytotoxis NVH 391-98|Rep:
AMP-dependent synthetase and ligase - Bacillus cereus
subsp. cytotoxis NVH 391-98
Length = 576
Score = 53.6 bits (123), Expect = 3e-05
Identities = 92/445 (20%), Positives = 174/445 (39%), Gaps = 30/445 (6%)
Query: 473 TLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLY 532
+ N+K ++ +L +A IG L+++G + + P ++ FY CL
Sbjct: 27 SFFNSKDKTFDYISYTDLSSQAFSIGAKLIDRGVEQRNLCMIVCSSPKYQVLY-FYACLS 85
Query: 533 VGAVPVTIRPPHPQNLHTTL-PTVRMIVD--VSKATLVLSNQSVIKLLRSKEASNVLDSK 589
+ A+P+ I P + + +L +R + S T +L ++ + + + + S + K
Sbjct: 86 INAIPLIIPSPKVLSGNDSLLKKIRYWANNKFSSRTFILVEEANVFEIIASQYSPLKVIK 145
Query: 590 AWPMTLDTDDMPKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKI 649
M +K+ PI + P+A +AY + ++TG + +SH + +
Sbjct: 146 CEEMEYSN---LRKERPINH-TPSANDIAYFQMTSASTGDGKAVAISHGNIIDNINGIHN 201
Query: 650 ACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIPPSEVEVNPALWLSAVSQYKV 709
A + S + L Y +G L S Y G L+ P E P WL +S K
Sbjct: 202 AVKCKQSEKVCSWLPLYHDMGLVGAELFSFYHGFDLFLMSPYEFLRKPIRWLETISNNKC 261
Query: 710 RDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVVAEERPRINLTNSFSKLFSAL 769
+ E ++ +N + + ++L+ + + AE L+ + K F
Sbjct: 262 TLSPSPNFGFEYASR----YINLNRVEDLDLSSWKAGLNGAEPIRSKTLSEFYVK-FKRY 316
Query: 770 GLSPRAVSTSFG-CRVNIAICLQGASSPEPSTVYVDLRALR-NDRVSLVERG-------- 819
G P A+ +G +A+ +P V V+ +++ + + G
Sbjct: 317 GFEPNAILPVYGLAEATLAVTFSKVGE-KPMYVIVEKGSVKLGTNIVIKSSGVFDPLNPP 375
Query: 820 --SPHSLCLMES-GKLLPGVKVITANPETKGQCGDSHLGEIWVQSPHNASGYFTIYGDES 876
+P S L S G + G+KV + + GEI + A GY T E
Sbjct: 376 NINPKSEILSFSVGTAIQGLKVQIIDELQNINNEELMCGEISILGNSIAIGYITA---EK 432
Query: 877 DYADHFSAQLVTGNTGEVYARTGYL 901
+ F ++ TG+ G +Y Y+
Sbjct: 433 KDIESFEKKINTGDLGFIYQGNLYV 457
>UniRef50_Q2H8G3 Cluster: Putative uncharacterized protein; n=1;
Chaetomium globosum|Rep: Putative uncharacterized protein
- Chaetomium globosum (Soil fungus)
Length = 2499
Score = 53.6 bits (123), Expect = 3e-05
Identities = 46/178 (25%), Positives = 82/178 (46%), Gaps = 17/178 (9%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPH 544
+T EL ++A ++ L ++ G V GD VAL+ +D + A G L GA + P +
Sbjct: 1499 VTYGELDRRANKMSRLFVQIG-VQPGDVVALMLDKSIDAVVAILGVLKAGAAYTPLSPEN 1557
Query: 545 PQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTD------ 598
P ++ +I++ S+A +++ +Q S + + L+T
Sbjct: 1558 PSERNS------LIINESQAKVLVIHQQHADFAHHHHPSPTSPTPLHTIVLNTTTAQTWL 1611
Query: 599 -DMPKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYP 655
P P ++ PT +LAYL ++ +TG GI++ HA+ + SM IA +P
Sbjct: 1612 ASQPPTN-PHIFTTPT--LLAYLLYTSGSTGQPKGIQVPHASAAAAVGSMIIAEGRHP 1666
>UniRef50_Q881Q3 Cluster: Non-ribosomal peptide synthetase, terminal
component; n=5; cellular organisms|Rep: Non-ribosomal
peptide synthetase, terminal component - Pseudomonas
syringae pv. tomato
Length = 5929
Score = 53.2 bits (122), Expect = 4e-05
Identities = 45/160 (28%), Positives = 74/160 (46%), Gaps = 17/160 (10%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPH 544
LT EL+ +A + + L+ G V D VA++ GL+ +CA L GA V + P H
Sbjct: 4805 LTYGELNHRANALAHYLIGLG-VRPDDRVAVLARRGLETLCAMLAVLKAGASYVPVDPAH 4863
Query: 545 PQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNV-LDSKAWPMTLDTDDMPKK 603
P + +++ S +VL+ ++ + V LD W L DD P
Sbjct: 4864 PDE------RIGYLLEDSAPVVVLAQFDLLARVPDLHVPRVALDRPDW---LQRDDTP-- 4912
Query: 604 KLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSL 643
+P + TAE LAY+ ++ +TG G+ + H + +L
Sbjct: 4913 HVPGL----TAENLAYVIYTSGSTGQPKGVMVEHRTLNNL 4948
Score = 51.6 bits (118), Expect = 1e-04
Identities = 52/212 (24%), Positives = 91/212 (42%), Gaps = 23/212 (10%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPH 544
L+ AEL+++A + + L+ G V + +A++ GLD + L GA V + P H
Sbjct: 3746 LSYAELNRQANSLAHYLISLG-VRPDERIAVVARRGLDTLVGLLAVLKAGACYVPVDPAH 3804
Query: 545 PQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNV-LDSKAWPMTLDTDDMPKK 603
P + ++ S VL+ Q+ I+ L + + LD WP
Sbjct: 3805 PGE------RIAYLLSDSAPVAVLAQQTFIERLPALGVPVIALDRPHWPEQAHN------ 3852
Query: 604 KLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIALCL 663
PI+ TA+ LAY+ ++ +TG G+ + H + +L A +L+ H A
Sbjct: 3853 --PIV-AGLTAKDLAYVIYTSGSTGQPKGVMVEHRTLENLVHWHCQAFDLHAGSHTA--- 3906
Query: 664 DPYCGLGF--ALWCLSSIYSGHHSILIPPSEV 693
G GF W + ++ +PP+E+
Sbjct: 3907 -SVAGFGFDAMAWEVWPALCAGATLHVPPAEI 3937
Score = 48.8 bits (111), Expect = 8e-04
Identities = 51/211 (24%), Positives = 90/211 (42%), Gaps = 16/211 (7%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPH 544
L+ EL+++A + + L+ G V D VA++ GL+ + + L GA V I P H
Sbjct: 572 LSYGELNQRANALAHHLISLG-VRPDDRVAVVARRGLETLVSLLAVLKSGAGYVPIDPAH 630
Query: 545 PQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKK 604
P V ++ S VL+ +++ L E ++ KA + L+ D P K
Sbjct: 631 PDE------RVAYLLTDSAPLAVLTQPALLPRL---EGLSLPGPKALLIDLERSDWPAKT 681
Query: 605 LPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIALCLD 664
T+ LAY+ ++ +TG G+ + H + +L A +L H A
Sbjct: 682 GNPQLADLTSSHLAYVIYTSGSTGQPKGVMVEHRTLNNLIDWHCEAFDLRAGSHTA---- 737
Query: 665 PYCGLGF--ALWCLSSIYSGHHSILIPPSEV 693
G GF W + ++ +PP+++
Sbjct: 738 SVAGFGFDAMAWEVWPALCAGATLHLPPADI 768
Score = 39.5 bits (88), Expect = 0.48
Identities = 57/232 (24%), Positives = 104/232 (44%), Gaps = 27/232 (11%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPH 544
LT EL+++A + + LL +G V +HVA++ P L+L+ + L +G T P
Sbjct: 2696 LTYGELNERANHLAHYLLGQG-VRPDEHVAILLPRSLELLISQ---LAIGKCAATYVP-- 2749
Query: 545 PQNLHTTLPTVRM--IVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPK 602
L P R ++ +A VL+ QS + + S + + LD L+ DD P
Sbjct: 2750 ---LDVNAPAERQQYMLGDCQAKCVLT-QSAMSIATSVQRID-LDQ------LNLDDQPA 2798
Query: 603 KKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIALC 662
+ A TA AY+ ++ +TG G+++ H + L + A E IA
Sbjct: 2799 HDPGLPQGADTA---AYVMYTSGSTGAPKGVRVGHRGIVRLVLNNGYA-EFNEQDSIAFA 2854
Query: 663 LDP-YCGLGFALWCLSSIYSGHHSILIPPSEVEVNPALWLSAVSQYKVRDTF 713
+P + +W ++ +G ++I + + ++PA + +A+ V F
Sbjct: 2855 SNPAFDASTMEVW--GALLNGGQLVVIEHTTL-IDPARFSAALRHGNVSVLF 2903
Score = 37.9 bits (84), Expect = 1.5
Identities = 39/156 (25%), Positives = 69/156 (44%), Gaps = 15/156 (9%)
Query: 488 AELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQN 547
A L+ +A +I + L+ G + D VA+ GL++I G L GA V + P +P
Sbjct: 1625 ATLNAQANKIAHRLIGLG-IGEDDRVAICTHRGLEMIAGLLGILKAGAAYVPLDPAYP-- 1681
Query: 548 LHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKKLPI 607
L + + S +LS +SV L + + +A D ++ +
Sbjct: 1682 ----LERIAYTLGDSAPVALLSQRSVQAALPVSQVPVISLDEA-----GLQDESERNPQV 1732
Query: 608 MYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSL 643
+ PT+ LAY+ ++ +TG+ G+ + H V L
Sbjct: 1733 SVK-PTS--LAYVIYTSGSTGLPKGVMIEHRNVARL 1765
>UniRef50_Q606X9 Cluster: Non-ribosomal peptide synthetase; n=1;
Methylococcus capsulatus|Rep: Non-ribosomal peptide
synthetase - Methylococcus capsulatus
Length = 1314
Score = 53.2 bits (122), Expect = 4e-05
Identities = 49/196 (25%), Positives = 91/196 (46%), Gaps = 18/196 (9%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPH 544
L+ EL +++ R+ LL +G V G VAL+ +L A +G L G + + P +
Sbjct: 481 LSYGELERRSNRLAAFLLNEG-VGPGSVVALLLDRSCELAVALFGVLKAGGAYLPLDPAY 539
Query: 545 PQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKK 604
P++ + +++ S A +VL+ ++ LR +L A T D D + +
Sbjct: 540 PED------RLAYMLEDSGARIVLTRNALADALRLP-GIELLRLDADRAT-DGDGLDEA- 590
Query: 605 LPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIALCLD 664
P P + +AYL ++ +TG G+ ++H + +LC +++ +L P +
Sbjct: 591 -PPCPAGP--DDIAYLMYTSGSTGQPKGVMVTHRGIVNLCAAIRRRYDLAPGDRVL---- 643
Query: 665 PYCGLGFALWCLSSIY 680
Y L F + C+ IY
Sbjct: 644 QYASLSFDI-CVEEIY 658
>UniRef50_Q3M5Z4 Cluster: AMP-dependent synthetase and ligase; n=5;
Bacteria|Rep: AMP-dependent synthetase and ligase -
Anabaena variabilis (strain ATCC 29413 / PCC 7937)
Length = 662
Score = 53.2 bits (122), Expect = 4e-05
Identities = 54/229 (23%), Positives = 106/229 (46%), Gaps = 16/229 (6%)
Query: 486 TCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPHP 545
T +L++ A R+ N LL G + GD +AL+ P + + ++ G L +GA+ V+I P
Sbjct: 28 TYKQLNEMANRVANALLGLG-IERGDRIALLLPNIPEFVISYLGILKIGAIAVSINP--- 83
Query: 546 QNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASN-----VLDSKAWPMTLDTDDM 600
NL + ++ I++ A ++++ +++ + L + + + + +A ++ M
Sbjct: 84 -NLQS--DELKFILNDCGAAVLVTTETLREKLPKVDLPHLKHIIIAEGQAGEAIALSEFM 140
Query: 601 PKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIA 660
+ A + ++ TTG G +SH V S SMK CE+ P+ I
Sbjct: 141 ANASPNARAVEIERDEPAAILYTSGTTGFPKGATLSHGNVISNMHSMKHCCEMRPNDQIL 200
Query: 661 LCLDPYCGLGFALWCLSSIYSGHHSILIPPSEVEVNPALWLSAVSQYKV 709
L L + G L+S + +I++ S +P L+ +S+Y +
Sbjct: 201 LFLPMFHCFGQNA-VLNSGLNTCATIILQRS---FDPETVLTTISEYNI 245
>UniRef50_Q5IW58 Cluster: Phosphinothricin tripeptide synthetase II;
n=2; Streptomyces viridochromogenes|Rep:
Phosphinothricin tripeptide synthetase II - Streptomyces
viridochromogenes
Length = 1086
Score = 53.2 bits (122), Expect = 4e-05
Identities = 59/213 (27%), Positives = 93/213 (43%), Gaps = 19/213 (8%)
Query: 446 SDAARKYQFISQILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKG 505
+D R ++ + +L A+ DH A A + LT EL + A R+ + LL G
Sbjct: 497 ADDPRHHRTLHGVLEDSARRHPDHT------AVEAPDRQLTYRELDEAANRLAHHLLALG 550
Query: 506 RVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKAT 565
V V + D I A + L GAV + + P +P + I+ S AT
Sbjct: 551 -VRPEQPVGVALDGTADAIVATFAVLKAGAVLLPLDPEYPAE------RLEHILRRSGAT 603
Query: 566 LVLSNQSVIKLLRSKEASNVL-DSKAWPMTLDTDDMPKKKLPIMYRAPTAEMLAYLDFSV 624
L+L+ +S+ + + VL D A L + LPI AP + LAY+ F+
Sbjct: 604 LLLTQRSLAGRFAGNDVTTVLLDDDATRAALADGPADRPGLPI---AP--DRLAYVIFTS 658
Query: 625 STTGMLAGIKMSHAAVTSLCRSMKIACELYPSR 657
+TG+ G+ + H + SL RS + + SR
Sbjct: 659 GSTGVPKGVMVPHRGIGSLTRSAEQFAQTPDSR 691
>UniRef50_Q8DTJ2 Cluster: Putative peptide synthetase; n=1;
Streptococcus mutans|Rep: Putative peptide synthetase -
Streptococcus mutans
Length = 633
Score = 52.8 bits (121), Expect = 5e-05
Identities = 78/364 (21%), Positives = 142/364 (39%), Gaps = 21/364 (5%)
Query: 550 TTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKKLPIMY 609
T ++ I +K L +I L + + VL K +LDT KK +
Sbjct: 84 TGFDSIEYIQGTNKVINKLKKPVLITELEKQCENIVLKDKFSLSSLDT----KKITGRVT 139
Query: 610 RAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGL 669
+ + + + + FS +TG G+ + +++ S+ + E I L +
Sbjct: 140 QNNSKDRIVMVQFSSGSTGEPKGVIYTDNTLSTNMFSILKSTEWKTEERILTWLTLTHNM 199
Query: 670 GFALWCLSSIYSGHHSILIPPSEVEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSS 729
G A L+ + G + L+P E V+P WL + +YK+ C +L K L ++
Sbjct: 200 GLASGHLAPLIKGMNQYLMPTREFIVHPINWLYQIDKYKINIVSCPNFASKLLIKTLNTT 259
Query: 730 -VNQLKSKGINLACVRTCVVVAEERPRINLTNSFSKLFSALGLSPRAVSTSFGCRVN-IA 787
+N + IN+ ++ E L +K S L + +G N +A
Sbjct: 260 KINDVDLSSINM------IINGSEPIDYGLCEELTKHLSKYKLRENCIYPVYGLAENTVA 313
Query: 788 ICLQGASSPEPSTVYVDLRALRNDRVSLVERGSPHSLCLMESGKLLPGVKVITANPETKG 847
CL A SP T+ + + +++ + S ++ GK + + + + K
Sbjct: 314 ACLPKAQSP-LKTITIGHEGVTVGEPAIIRKES-EGYRVVSVGKAISETDIRIVDNDNK- 370
Query: 848 QCGDSHLGEIWVQSPHNASGYFTIYGDESDYADHFS--AQLVTGNTGEVYARTGYLGFLR 905
+ + G I + GY Y +E + FS L TG+ G ++ Y+ F R
Sbjct: 371 ILPEGYYGNIELNGLSVTPGY---YNNEKESEKIFSDDGWLKTGDQGLIFDNELYI-FGR 426
Query: 906 RTEI 909
EI
Sbjct: 427 EKEI 430
Score = 39.9 bits (89), Expect = 0.36
Identities = 29/132 (21%), Positives = 57/132 (43%), Gaps = 5/132 (3%)
Query: 18 EHMVCVLDFKRETGLWHAVLASVLNGMHVIFIPYALMKVSPASWMHMITKHRASIAIVK- 76
E ++ L GL LA ++ GM+ +P V P +W++ I K++ +I
Sbjct: 187 ERILTWLTLTHNMGLASGHLAPLIKGMNQYLMPTREFIVHPINWLYQIDKYKINIVSCPN 246
Query: 77 -SRDLHWGLLATRDHKEISLSSLRMLLVADGANPWSLSSCDQFLSVFQSKGVRGDAICPC 135
+ L L T ++ LSS+ M++ +G+ P C++ +R + I P
Sbjct: 247 FASKLLIKTLNTTKINDVDLSSINMII--NGSEPIDYGLCEELTKHLSKYKLRENCIYPV 304
Query: 136 -ACSSESMTVCI 146
+ ++ C+
Sbjct: 305 YGLAENTVAACL 316
>UniRef50_Q2SG85 Cluster: Acyl-CoA synthetases
(AMP-forming)/AMP-acid ligases II; n=1; Hahella
chejuensis KCTC 2396|Rep: Acyl-CoA synthetases
(AMP-forming)/AMP-acid ligases II - Hahella chejuensis
(strain KCTC 2396)
Length = 552
Score = 52.8 bits (121), Expect = 5e-05
Identities = 63/333 (18%), Positives = 137/333 (41%), Gaps = 17/333 (5%)
Query: 455 ISQILRWRAQSTSDHVIFTLLNAKGAVSKV-LTCAELHKKAERIGNLLLEKGRVNTGDHV 513
++ +L +S+ I T LN G + + T ++L ++ + L + +N
Sbjct: 14 VATLLVEALKSSPQPYILTYLNKGGELGETRYTPSQLLAESAQYAERL--RADMNGARTA 71
Query: 514 ALIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSV 573
L PG + A GC++ G + + P + ++ I+ S ++ + +
Sbjct: 72 LLSMEPGCHFVIALLGCIFSGITAIPVPAPRSPK---EMVRLQAIMSDSHTRQIICDANT 128
Query: 574 IKLLRSKEASNVLDSKAWPMTLDTDDMPKKKLPIMYRAPTAEMLA-----YLDFSVSTTG 628
+ + KE S+ + +++D +++ + + ++ + ++ +T
Sbjct: 129 LAYFQ-KETSDDDRLQLIHISIDANEVDSRAGAFIQEPTITPFISPHEPVIIQYTSGSTK 187
Query: 629 MLAGIKMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILI 688
G+K+S + + R P +++ L Y +G + + +G IL+
Sbjct: 188 APRGVKVSERNILANQRISAEKWRFAPEKNMLSWLPHYHDMGLFGSIIYPLMTGMQCILM 247
Query: 689 PPSEVEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRTCVV 748
P + P WLSAVS+++ + +LC L + + +G++L+C +
Sbjct: 248 SPVDFIKQPLRWLSAVSKHRAAISGGPAFAYQLC---LDIAPDDF-IRGLDLSCWQAAYC 303
Query: 749 VAEERPRINLTNSFSKLFSALGLSPRAVSTSFG 781
A+ P L + K FSA GL R+V +G
Sbjct: 304 GADYVPH-QLLENVRKRFSAAGLHSRSVLACYG 335
Score = 35.5 bits (78), Expect = 7.8
Identities = 19/74 (25%), Positives = 41/74 (55%), Gaps = 2/74 (2%)
Query: 1 MLAHCRMLSVACNYTEGEHMVCVLDFKRETGLWHAVLASVLNGMHVIFI-PYALMKVSPA 59
+LA+ R+ + + ++M+ L + GL+ +++ ++ GM I + P +K P
Sbjct: 199 ILANQRISAEKWRFAPEKNMLSWLPHYHDMGLFGSIIYPLMTGMQCILMSPVDFIK-QPL 257
Query: 60 SWMHMITKHRASIA 73
W+ ++KHRA+I+
Sbjct: 258 RWLSAVSKHRAAIS 271
>UniRef50_Q08QA2 Cluster: Linear gramicidin synthetase subunit B; n=1;
Stigmatella aurantiaca DW4/3-1|Rep: Linear gramicidin
synthetase subunit B - Stigmatella aurantiaca DW4/3-1
Length = 1691
Score = 52.8 bits (121), Expect = 5e-05
Identities = 48/175 (27%), Positives = 76/175 (43%), Gaps = 14/175 (8%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPH 544
LT L + ++R L+ +G V++ + VA++ P LDL A +G L GA V + P H
Sbjct: 872 LTYRALDEASDRWARWLVSQG-VHSEERVAVLLEPSLDLAIALWGILKAGAAYVPLNPDH 930
Query: 545 PQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKK 604
P H + T + + L + S L + + A L T
Sbjct: 931 PAERHEHVLTQAGV----RTVLTHGHLSAPALHNRPGVFRMEEHAAQVSALPTG------ 980
Query: 605 LPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHI 659
P+ R A+ LAY+ ++ TTG GI++SH V +L S + L P +
Sbjct: 981 APVHVR---ADQLAYVLYTSGTTGAPRGIEISHLGVHNLIDSTQREYNLQPGEAV 1032
>UniRef50_A1G2R8 Cluster: Amino acid adenylation domain; n=1;
Salinispora arenicola CNS205|Rep: Amino acid adenylation
domain - Salinispora arenicola CNS205
Length = 1045
Score = 52.8 bits (121), Expect = 5e-05
Identities = 52/195 (26%), Positives = 88/195 (45%), Gaps = 23/195 (11%)
Query: 455 ISQILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVA 514
+ ++ +AQST D V A ++ +T AEL + R+ + L G V +G VA
Sbjct: 450 VDGLIAVQAQSTPDAV------AVRTTAEDITYAELDTRVNRLAHHLRALG-VRSGSLVA 502
Query: 515 LIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVI 574
++ G DL+ A L G V I P +P D A +V+ + + +
Sbjct: 503 VLLDRGPDLLTALLAVLRAGGAYVPIDPEYP--------------DARVAFIVVDSAAEV 548
Query: 575 KLLRSKEASNVLDSKAWPMTLDTDD--MPKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAG 632
+ RS A V D+ + LD D + ++ + TA+ LAYL ++ +TG G
Sbjct: 549 VITRSTLADRVGDTDGKLVLLDRDRAAVAARRADAVGPTATADDLAYLIYTSGSTGTPKG 608
Query: 633 IKMSHAAVTSLCRSM 647
+ + H A+T+ S+
Sbjct: 609 VMVHHRALTNFVTSI 623
>UniRef50_Q0CTP0 Cluster: Predicted protein; n=2; Aspergillus|Rep:
Predicted protein - Aspergillus terreus (strain NIH 2624)
Length = 2923
Score = 52.8 bits (121), Expect = 5e-05
Identities = 41/166 (24%), Positives = 75/166 (45%), Gaps = 14/166 (8%)
Query: 482 SKVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIR 541
++ ++ A L +A R+ N L+ G V G+ V L+ +D I A G + GA V +
Sbjct: 1480 TEAVSYAHLDARATRLANFLIRAG-VQVGEAVPLMLDKSIDTIVAILGVMKAGAAYVPLS 1538
Query: 542 PPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMP 601
P +P + + + + DV A L+++ + L+R V + D MP
Sbjct: 1539 PDNPVDRNAFI-----VSDVG-ARFALAHEEYLDLIRGDSNLKVFRIDDPEIDALPDTMP 1592
Query: 602 KKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSM 647
++ + +AY+ ++ +TGM G+K+ H A + SM
Sbjct: 1593 DVQI-------ATDSIAYIIYTSGSTGMPKGVKVPHQAAAAAVTSM 1631
>UniRef50_Q8VQF8 Cluster: Peptide synthetase XpsB; n=1; Xenorhabdus
bovienii|Rep: Peptide synthetase XpsB - Xenorhabdus
bovienii
Length = 3316
Score = 52.4 bits (120), Expect = 6e-05
Identities = 45/172 (26%), Positives = 82/172 (47%), Gaps = 10/172 (5%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPH 544
L+ +EL+++A ++ + ++ G V+ D VA+ LD++ F G L GA + + P H
Sbjct: 532 LSYSELNQRANQLAHSIMASG-VHPDDRVAICAERSLDMVIGFVGILKAGASYIPLDPNH 590
Query: 545 PQNLHTTLPTVRMIVDVSKATLVLSNQSV-IKLLRSKEASNVLDSKAWPMTLDTDDMPKK 603
P T M+ D S+ L+L+ Q + +L + LDS+ + + PK
Sbjct: 591 P-----TERLAYMLSD-SQPVLMLTQQHLKARLPVTNIPVWALDSEEHQTCIAS--QPKD 642
Query: 604 KLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYP 655
+ T++ LAY+ ++ +TG+ G+ + H V L S +L P
Sbjct: 643 NIDASQLGLTSQNLAYVLYTSGSTGLPKGVMIEHQNVVHLIHSQFQMSKLTP 694
Score = 40.7 bits (91), Expect = 0.21
Identities = 38/163 (23%), Positives = 71/163 (43%), Gaps = 18/163 (11%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPH 544
LT EL+++A ++ + L+ G V D VA+ LD++ + G L GA V + P +
Sbjct: 2709 LTYTELNQRANQLAHHLISSG-VQPDDRVAICIERNLDMVISMLGILKAGAGYVPLDPAY 2767
Query: 545 PQN-----LHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDD 599
P L + P + + + L + + V +L + S V TD+
Sbjct: 2768 PAERLAYILSDSAPKLLLTQQHLQGRLAVEDLPVWRLDDADHLSTVAQQP-------TDN 2820
Query: 600 MPKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTS 642
++L + LAY+ ++ +TG+ G+ + H V +
Sbjct: 2821 PDSRRLELQ-----PHHLAYIIYTSGSTGLPKGVMIEHRNVVN 2858
>UniRef50_A4KVL6 Cluster: Non-ribosomal peptide synthetase modules;
n=1; Sinorhizobium meliloti|Rep: Non-ribosomal peptide
synthetase modules - Rhizobium meliloti (Sinorhizobium
meliloti)
Length = 2146
Score = 52.4 bits (120), Expect = 6e-05
Identities = 62/240 (25%), Positives = 101/240 (42%), Gaps = 27/240 (11%)
Query: 486 TCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPHP 545
T EL+ +A + + L+E G V G VA+ G+D+I A L GA V I P +P
Sbjct: 1563 TYRELNSRANALAHRLIELG-VKPGSRVAICIERGVDMIVALIATLKAGAAYVPIDPAYP 1621
Query: 546 QNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNV-LDSKAWP-MTLDTDDMPKK 603
+ + I + TLVL+ ++ L + + +D P + D D+P
Sbjct: 1622 KE------RIAFIAADANVTLVLTQSALSGELTGASGTLIAVDELKTPAIACDNPDVPV- 1674
Query: 604 KLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIALCL 663
A LAY+ ++ +TG G+ M H + SL R + A P+ L
Sbjct: 1675 ---------AAGCLAYIIYTSGSTGKPKGVVMPHGPLASLIR-WQTARSALPTGAPTL-- 1722
Query: 664 DPYCGLGFAL---WCLSSIYSGHHSILIPPSEVEVNPALWLSAVSQYKVRDTFCSYGVME 720
+ L F + S++ +G +LI + PALW + + VR F Y ++
Sbjct: 1723 -QFASLSFDVSFQEIFSTLGAGGTLVLINEDQRRDPPALW-ELLHEEDVRRLFMPYVALQ 1780
>UniRef50_UPI0000DAE7B3 Cluster: hypothetical protein
Rgryl_01001237; n=1; Rickettsiella grylli|Rep:
hypothetical protein Rgryl_01001237 - Rickettsiella
grylli
Length = 596
Score = 52.0 bits (119), Expect = 8e-05
Identities = 55/216 (25%), Positives = 98/216 (45%), Gaps = 28/216 (12%)
Query: 489 ELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNL 548
EL+K++ ++ + L K V G VALI L+ + + +GA V I P +P
Sbjct: 29 ELNKQSNQLAHYLKSKA-VRNGTSVALISENFLERVISILALWKLGAAYVPIDPNYPST- 86
Query: 549 HTTLPTVRMIVDVSKATLVLSNQSVIK--LLRSKEASNVLDSKAWPMT-LDTDDMPKKKL 605
+ I++ SK +++++ + K L S +LDSK P DD+
Sbjct: 87 -----RINFIMNDSKVNFIITDEEIYKKYFLNSSLTIILLDSKNNPKNNFSKDDLNDTM- 140
Query: 606 PIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACEL-YPSRHIALCLD 664
A+ +AY+ ++ +TG G+ ++HA ++S+ + K L Y RH+ +
Sbjct: 141 -------GADTIAYIAYTSGSTGKPKGVPITHANISSIYEAWKQVYHLTYLDRHLQI--- 190
Query: 665 PYCGLGFALWCLSSIYSGHHS---ILIPPSEVEVNP 697
GF + C I S ++I P+E+ +NP
Sbjct: 191 --ANFGFDV-CSGDIIRALASGAQLVICPTEIILNP 223
>UniRef50_Q7N1E2 Cluster: Similar to proteins involved in antibiotic
biosynthesis; n=1; Photorhabdus luminescens subsp.
laumondii|Rep: Similar to proteins involved in
antibiotic biosynthesis - Photorhabdus luminescens
subsp. laumondii
Length = 3270
Score = 52.0 bits (119), Expect = 8e-05
Identities = 41/165 (24%), Positives = 80/165 (48%), Gaps = 14/165 (8%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPH 544
LT A+L+ +A ++ + L +G V+T VA++ +D+I A + GA V + P
Sbjct: 559 LTYAQLNARANQLAHQLRAQG-VSTSGRVAVLLQRSIDMITALLAVMKAGAAYVPVDPSF 617
Query: 545 PQNLHTTLPTVRMIVDVSKATLVLSNQSVI-KLLRSKEASNVLDSKAWPMTLDTDDMPKK 603
P + V+ +++ ++ ++SN+ + + E + +LD +D P
Sbjct: 618 P------VDRVQYMLNDAEPQCIISNREYASRSVGFAELTCLLDH------IDLSQSPTT 665
Query: 604 KLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMK 648
+P A LAY+ ++ +TG G+ +SH+AV + SM+
Sbjct: 666 NIPKQSIGLAASALAYVIYTSGSTGKPKGVMVSHSAVNNFLISMQ 710
Score = 49.2 bits (112), Expect = 6e-04
Identities = 37/159 (23%), Positives = 77/159 (48%), Gaps = 12/159 (7%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPH 544
LT A+L+ KA ++ + L+ +G +A+ +D++ + L G+ + + P +
Sbjct: 1616 LTYAQLNAKANQLAHYLVAQG-AKPDSMIAICIERSIDMVVSVLAILKSGSAYLPLDPAY 1674
Query: 545 PQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKK 604
PQ + I+D ++ +V++N KLL ++ + L TD++P +
Sbjct: 1675 PQE------RLAYIIDDAQPLMVITNSHNQKLLPENSLFSIDVTTTSFAELSTDNIPAVE 1728
Query: 605 LPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSL 643
L + + LAY+ ++ +TGM G+ + H A+ +L
Sbjct: 1729 LGLC-----STHLAYVLYTSGSTGMPKGVMIEHQALVNL 1762
>UniRef50_Q3WHQ1 Cluster: Non-ribosomal peptide synthase:Amino acid
adenylation; n=2; Frankia sp. EAN1pec|Rep: Non-ribosomal
peptide synthase:Amino acid adenylation - Frankia sp.
EAN1pec
Length = 4554
Score = 52.0 bits (119), Expect = 8e-05
Identities = 43/159 (27%), Positives = 72/159 (45%), Gaps = 7/159 (4%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPH 544
L A+ + + +LL E+G V G VA+ P DL+ + L GA V + P +
Sbjct: 507 LVYAQFDARVNALAHLLTERG-VRVGGRVAVALPRSADLVTSLAAVLRAGAAYVPVDPGY 565
Query: 545 P-QNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKK 603
P + + L V ++ + +++ V L + + VLD A ++
Sbjct: 566 PAERIAAILQDSGARVAITDSATAVAHAGV--LTAAGVVTVVLDEDAVRGQIEHG---AP 620
Query: 604 KLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTS 642
P++ R T + AY+ F+ TTG GI +SHAAV +
Sbjct: 621 DAPVLPRPLTPDDTAYVIFTSGTTGRPKGIALSHAAVVN 659
Score = 37.9 bits (84), Expect = 1.5
Identities = 41/169 (24%), Positives = 71/169 (42%), Gaps = 16/169 (9%)
Query: 480 AVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVT 539
A ++ T A L + R LLLE+G V +AL+ P ++ A + VGA V
Sbjct: 2378 AGARSFTFAGLSAEVNRYARLLLERG-VRQEHRIALLLPRDERMVIAMFAVFAVGAAYVP 2436
Query: 540 IRPPHPQN-----LHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMT 594
I P + L PTV ++ D A L + V+ L + + V + P+T
Sbjct: 2437 IDAELPDDRIGYMLDVAGPTVTLVTDRDVARLGPAAGRVVNLDDAVVRARVAELADGPVT 2496
Query: 595 LDTDDMPKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSL 643
+ + + LAY+ F+ +TG G+ + + +T++
Sbjct: 2497 VAERG----------GEVSLDHLAYIIFTSGSTGRPKGVAVGYRGLTNM 2535
Score = 37.9 bits (84), Expect = 1.5
Identities = 41/169 (24%), Positives = 71/169 (42%), Gaps = 16/169 (9%)
Query: 480 AVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVT 539
A ++ T A L + R LLLE+G V +AL+ P ++ A + VGA V
Sbjct: 3469 AGARSFTFAGLSAEVNRYARLLLERG-VRQEHRIALLLPRDERMVIAMFAVFAVGAAYVP 3527
Query: 540 IRPPHPQN-----LHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMT 594
I P + L PTV ++ D A L + V+ L + + V + P+T
Sbjct: 3528 IDAELPDDRIGYMLDVAGPTVTLVTDRDVARLGPAAGRVVNLDDAVVRARVAELADGPVT 3587
Query: 595 LDTDDMPKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSL 643
+ + + LAY+ F+ +TG G+ + + +T++
Sbjct: 3588 VAERG----------GEVSLDHLAYIIFTSGSTGRPKGVAVGYRGLTNM 3626
>UniRef50_Q02HM0 Cluster: Putative non-ribosomal peptide synthetase;
n=1; Pseudomonas aeruginosa UCBPP-PA14|Rep: Putative
non-ribosomal peptide synthetase - Pseudomonas
aeruginosa (strain UCBPP-PA14)
Length = 1113
Score = 52.0 bits (119), Expect = 8e-05
Identities = 58/231 (25%), Positives = 110/231 (47%), Gaps = 29/231 (12%)
Query: 484 VLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGA--VPVTIR 541
VL+ EL ++A ++ LL G + G+ VA+ P GLD + A +G L GA VPV +
Sbjct: 540 VLSYGELARRALQVAALLHRHG-IEPGEPVAISLPRGLDQVTAVFGVLAAGACYVPVGMS 598
Query: 542 PPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLD-SKAWPMTLDTDDM 600
P + I + + VL++ S + ++ ++E + LD + AW + D
Sbjct: 599 QPAARQAR--------IHETAGIRWVLTDSSGV-VMATREGTTRLDVASAWHI-----DP 644
Query: 601 PKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYP-SRHI 659
P + P+ A+ AY+ F+ +TG G++++HAA + + + P SR +
Sbjct: 645 PSEYQPVR-----ADSSAYIIFTSGSTGEPKGVEVTHAAAANTIDVLNARYGVGPDSRVL 699
Query: 660 AL-CLDPYCGLGFALWCLSSIYSGHHSILIPPSEVEVNPALWLSAVSQYKV 709
A+ LD +++ L + ++++ + + A WL + Q++V
Sbjct: 700 AVSSLD----FDLSVYDLFGVLGVGGAVVLLDEDHRRDAAAWLELIHQHRV 746
>UniRef50_A7F7R1 Cluster: Putative uncharacterized protein; n=1;
Sclerotinia sclerotiorum 1980|Rep: Putative
uncharacterized protein - Sclerotinia sclerotiorum 1980
Length = 2282
Score = 52.0 bits (119), Expect = 8e-05
Identities = 42/171 (24%), Positives = 80/171 (46%), Gaps = 13/171 (7%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPH 544
LT AEL +++ I LL++G + GD VA+ P +D +C+ + V A+ V
Sbjct: 1661 LTYAELERRSNNIAQELLKQG-LCPGDRVAIFQEPSVDWVCSVLAIMRVAAIYV------ 1713
Query: 545 PQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKE--ASNVLDSKAWPMTLDTDDMPK 602
P +L + +++IV +S A ++L + + + +++ E V++ A D
Sbjct: 1714 PLDLRNPISRLKIIVSISNAAIILVHNATLADVKNLEFTPDKVVNISAVHAATPLDSTEH 1773
Query: 603 KKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACEL 653
+ A+ A + F+ +TG GI ++HA++ S +A L
Sbjct: 1774 TSM----NNSRADSPAVILFTSGSTGTPKGITLTHASLRCAIESHVVAMRL 1820
>UniRef50_Q3KE51 Cluster: Amino acid adenylation; n=7;
Pseudomonas|Rep: Amino acid adenylation - Pseudomonas
fluorescens (strain PfO-1)
Length = 5422
Score = 51.6 bits (118), Expect = 1e-04
Identities = 48/176 (27%), Positives = 78/176 (44%), Gaps = 16/176 (9%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPH 544
LT +L+++A R+ + L+ G V D VAL G ++ L GA V + P H
Sbjct: 2724 LTYGQLNQRANRLAHHLIGLG-VQPDDRVALCVRRGPQMLVGLLAILKAGAGYVPVDPAH 2782
Query: 545 PQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKK 604
P + ++ S VL+ S +LL + LDS AW D++ +
Sbjct: 2783 PAE------RIAYLLQDSDPVAVLAQASTRELLGMMPVID-LDSDAWQHLPDSNP----Q 2831
Query: 605 LPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIA 660
LP + T LAY+ ++ +TG G+ + HA + +L A +L+ H A
Sbjct: 2832 LPYL----TPANLAYVIYTSGSTGQPKGVMVEHATLENLVHWHAEAFDLHAGSHTA 2883
Score = 48.0 bits (109), Expect = 0.001
Identities = 52/184 (28%), Positives = 85/184 (46%), Gaps = 25/184 (13%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICA--FYGCLYVGAVPVTIRP 542
LT EL+++A R+ + L+ +G V GD VA++ P LDL+ A G VP+ I
Sbjct: 1650 LTYDELNQRANRLAHFLIGQG-VQPGDPVAILLPRSLDLLAAQLAIGKCAAAYVPLDINA 1708
Query: 543 PHPQNLHTTLPTVRMIVDVS-KATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMP 601
P + M+ D S K L LS ++V +R + LDS + LD +
Sbjct: 1709 PGERQAF-------MVEDSSAKVLLTLSTETVDYAVRRID----LDS----LPLDAQPVH 1753
Query: 602 KKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIAL 661
LP ++E +AY+ ++ +TG G+ + H A+ L + A + P +A
Sbjct: 1754 NPGLP-----QSSESVAYIMYTSGSTGTPKGVMVPHRAIGRLVINNGYA-DFNPQDRVAF 1807
Query: 662 CLDP 665
+P
Sbjct: 1808 ASNP 1811
Score = 45.2 bits (102), Expect = 0.010
Identities = 45/160 (28%), Positives = 71/160 (44%), Gaps = 16/160 (10%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPH 544
LT AEL+ +A R+ + L E G V VA+ GL+L+ G L G V + P +
Sbjct: 3787 LTYAELNAQANRLAHHLRELG-VGPDSRVAISVERGLELMVGLLGILKAGGAYVPLDPAY 3845
Query: 545 PQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNV-LDSKAWPMTLDTDDMPKK 603
P + ++ S VL + + +LL A + LD W T + DD P+
Sbjct: 3846 PAE------RLDYMLKDSAPVAVLVHGATRELLDESTALVIDLDQAHW--TFNPDDNPQ- 3896
Query: 604 KLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSL 643
+A LAY+ ++ +TG G+ + H V +L
Sbjct: 3897 -----VLGLSASNLAYVIYTSGSTGAPKGVMVEHRGVGNL 3931
>UniRef50_Q0SK68 Cluster: Non-ribosomal peptide synthetase; n=1;
Rhodococcus sp. RHA1|Rep: Non-ribosomal peptide
synthetase - Rhodococcus sp. (strain RHA1)
Length = 8871
Score = 51.6 bits (118), Expect = 1e-04
Identities = 50/212 (23%), Positives = 93/212 (43%), Gaps = 20/212 (9%)
Query: 483 KVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRP 542
++LT AEL + R+ + L +G + T VAL+ P ++++ A Y + GA + + P
Sbjct: 2864 RILTYAELDTWSTRLAHSFLARG-IGTESIVALVIPRSVEMLAAMYAVVKSGAAVLALDP 2922
Query: 543 PHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNV--LDSKAWPMTLDTD-D 599
HP + +L I S A +V + + + + + +D +A TD D
Sbjct: 2923 SHPTDRIESL-----IQSASAALVVTTGDADVPVPTGLPVARFDDIDHEARDTAPVTDVD 2977
Query: 600 MPKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHI 659
P + LAY+ ++ +TG G+ +SHAA+ + + ++ H
Sbjct: 2978 RGASLHP--------DNLAYVVYTSGSTGAPKGVAVSHAAIANQLAWSQAQLPIH--EHD 3027
Query: 660 ALCLDPYCGLGFALW-CLSSIYSGHHSILIPP 690
A+W C +++ SG +L+PP
Sbjct: 3028 RTVQKAPIAFDVAIWECFAALCSGSVLVLLPP 3059
Score = 42.3 bits (95), Expect = 0.068
Identities = 42/171 (24%), Positives = 75/171 (43%), Gaps = 13/171 (7%)
Query: 483 KVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRP 542
+ LT A L + R+ L+E G VA+ PP +DL+ A GA + +
Sbjct: 5454 ETLTYAALGARVYRLARHLVELGAA-PDTVVAVALPPSIDLVVALLAAQQAGAGYLALDV 5512
Query: 543 PHP-QNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEA--SNVLDSKAWPMTLDTDD 599
HP L T+ D + LV + +L R+ ++ D++A + L D
Sbjct: 5513 GHPADRLDATMS------DAAPVCLVSTTDHAARLRRNLPTVLADDADTRAHLLDLSPDP 5566
Query: 600 MPKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIA 650
+ P A T + +AY+ ++ +TG G+ ++H +T+L + + A
Sbjct: 5567 ITD---PERRAALTPDAVAYVVYTSGSTGRPKGVVVTHRNLTTLFDNTRTA 5614
Score = 38.7 bits (86), Expect = 0.84
Identities = 44/212 (20%), Positives = 87/212 (41%), Gaps = 14/212 (6%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPH 544
+T +L ++ ++ +LL +G VAL P DL+ A + GA + + P +
Sbjct: 732 ITYRQLDAESTQLARVLLSRG-AGPETVVALALPRSADLVRAVWAVAKSGAAFLPVDPGY 790
Query: 545 PQNLHTTLPT---VRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMP 601
P+ + T + V VS+ L L + A + + D D
Sbjct: 791 PEARIAHMLTDSGANLGVTVSRHRGDLPGDVEWIELHDRNADDTTSVRTSTPVGDAD--- 847
Query: 602 KKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIAL 661
+ P+ + P AYL ++ +TG+ G+ ++H + +L + ++ P+ +A
Sbjct: 848 -RPRPLRWDHP-----AYLIYTSGSTGVPKGVVVTHRGIANLIAAQIKGLDVPPTGRVAQ 901
Query: 662 CLDPYCGLGFALWCLSSIYSGHHSILIPPSEV 693
P L+++ SG +++PP V
Sbjct: 902 FASPSFDASL-FELLAAVGSGARVVIVPPEVV 932
Score = 38.3 bits (85), Expect = 1.1
Identities = 42/168 (25%), Positives = 72/168 (42%), Gaps = 19/168 (11%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPH 544
LT AEL +A + + L+E G V VA+ P L+ + A + GA V + P +
Sbjct: 4396 LTYAELEARALLLADRLVESG-VGPESVVAIAIPRSLESVLAVWAVAGTGAAFVPVDPTY 4454
Query: 545 PQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDD--MPK 602
PQ +R+ +V + ++ L S + D+ W T +P
Sbjct: 4455 PQ--------IRI------QHMVADSGVLVGLTTSSRRDALPDTVTWIDIEGTGAGRLPH 4500
Query: 603 KKLPIMYRAPTA--EMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMK 648
+ APT + AYL ++ +TG+ G+ + H V SL +++
Sbjct: 4501 AGVSEACPAPTIRPDNAAYLIYTSGSTGVPKGVVVGHRGVNSLATTLR 4548
Score = 37.5 bits (83), Expect = 1.9
Identities = 44/210 (20%), Positives = 86/210 (40%), Gaps = 12/210 (5%)
Query: 483 KVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRP 542
+ LT +L + + + LL+ +G V G VAL P + + A + GA V + P
Sbjct: 8054 RALTYRQLGEDSAQFARLLIARGAVPEGV-VALALPRSIAWVRAVWAVARSGAASVPVDP 8112
Query: 543 PHP-QNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMP 601
+P + L + ++ A ++ L + ++ +P T TD
Sbjct: 8113 TYPLTRIAHMLADAGAALGLTVAGYRAQLPDTVEWLVLDDPDFETQTRHFPSTPVTD--V 8170
Query: 602 KKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIAL 661
+ P+ P AYL ++ +TG G+ +SH + +L + + P ++
Sbjct: 8171 DRTAPLRTDNP-----AYLIYTSGSTGAPKGVVVSHRGLANLFEQERHHLHVTPDARVSH 8225
Query: 662 CLDPYCGLGFALWCLSSIY-SGHHSILIPP 690
P +L+ L+ + +G +L+PP
Sbjct: 8226 LASP--SFDASLFELTMAFCAGAQVVLVPP 8253
>UniRef50_A4KUB7 Cluster: TlmIV; n=3; root|Rep: TlmIV -
Streptoalloteichus hindustanus
Length = 2620
Score = 51.6 bits (118), Expect = 1e-04
Identities = 58/233 (24%), Positives = 101/233 (43%), Gaps = 21/233 (9%)
Query: 480 AVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVT 539
A +T +L+ +A ++ L +G V D VAL P LD + A G L G V
Sbjct: 514 AAGHQITYRQLNARANQLARRLRARG-VRAEDRVALFLPRSLDSVTAMLGILKAGGAYVP 572
Query: 540 IRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDD 599
+ P HP T L V I D + LV + + + + +LDS+ L T+D
Sbjct: 573 LDPDHPS---TRLSAV--IADAAPTLLVTTKEIQDRCPEYRGPVLLLDSER--DALSTED 625
Query: 600 MPKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHI 659
+LP+ A+ LAY+ + +TG G+ H + + ++YP +
Sbjct: 626 TADLRLPV-----RADNLAYVLHTSGSTGRPKGVLGLHRGAVNRAAWWE---KVYPFQPG 677
Query: 660 ALCLDPYCGLGF--ALW-CLSSIYSGHHSILIPPSEVEVNPALWLSAVSQYKV 709
+C LGF ++W + +G +++ P EV +P + ++ ++V
Sbjct: 678 EVCA-ARTALGFVDSVWETFGPLIAGVPLLVLSPDEV-ADPVRLVDRLAAHRV 728
Score = 39.1 bits (87), Expect = 0.63
Identities = 50/231 (21%), Positives = 92/231 (39%), Gaps = 16/231 (6%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPH 544
+T EL ++ R+ L G G+ VA++ G + A G L GA V + P
Sbjct: 1585 VTYRELAARSHRVARALRRLG-AKPGELVAIVARKGWQQVVAALGVLESGAAFVPVDPDL 1643
Query: 545 PQNLHTTLPTVRMIVDVSKATLVLSNQ----SVIKLLRSKEASNVLDSKAWP--MTLDTD 598
P T L R ++ L ++ + + +L + S + D+ A LD
Sbjct: 1644 PAARLTHL-LHRAEARIALTHLAVAEEVPFPDDLSVLAVDDDSALQDNSALQDNSALDAS 1702
Query: 599 DMPKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRH 658
D P + RA + LAY+ F+ +TG G+ + H + R + + P H
Sbjct: 1703 DEP------LDRAQGMDDLAYVIFTSGSTGEPKGVMIDHRGAANTIRCVNQHFAVGP--H 1754
Query: 659 IALCLDPYCGLGFALWCLSSIYSGHHSILIPPSEVEVNPALWLSAVSQYKV 709
+ A++ L + + ++++P +PA W V+ ++
Sbjct: 1755 DRVLAVSSLSFDLAIYDLFGVLAAGGTVVLPRHSRRRDPAHWAELVATERI 1805
>UniRef50_A4C380 Cluster: Putative uncharacterized protein; n=1;
Pseudoalteromonas tunicata D2|Rep: Putative
uncharacterized protein - Pseudoalteromonas tunicata D2
Length = 1167
Score = 51.6 bits (118), Expect = 1e-04
Identities = 46/205 (22%), Positives = 91/205 (44%), Gaps = 14/205 (6%)
Query: 441 GYTDDSDAARKYQFISQILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNL 500
G + S + I QI + T D++ L G S LT EL+++A ++ +
Sbjct: 534 GLNNHSQDYPNHLCIQQIFEQQVLRTPDNIAVKL----GKNS--LTYKELNERANQLAHF 587
Query: 501 LLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVD 560
L+ + ++ + L L+++ L GA V + P +P+ T + +
Sbjct: 588 LIREYQITPDTFIGLCVERSLEMVIGTLAILKAGAAYVPLDPAYPRQRLTYM------MS 641
Query: 561 VSKATLVLSNQSVIKLLRSKEASNV-LDSKAWPMTLDT-DDMPKKKLPIMYRAPTAEMLA 618
S ++LS +IK L + S+V +D ++ T+ T + PK L + ++ LA
Sbjct: 642 NSGVKIILSTHFIIKQLDLTDYSSVCIDGLSYAQTVKTFANYPKHNLGDLVSGLSSNHLA 701
Query: 619 YLDFSVSTTGMLAGIKMSHAAVTSL 643
Y ++ +TG G+ + H + ++
Sbjct: 702 YAIYTSGSTGQPKGVLLEHKGIVNV 726
>UniRef50_Q0CCY6 Cluster: Predicted protein; n=2; Pezizomycotina|Rep:
Predicted protein - Aspergillus terreus (strain NIH 2624)
Length = 2610
Score = 51.6 bits (118), Expect = 1e-04
Identities = 44/169 (26%), Positives = 78/169 (46%), Gaps = 12/169 (7%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPH 544
L+ AE H + + L G V TGD + L ++ + A +G L GA + P +
Sbjct: 1580 LSYAEFHSAVASMASYLRTLG-VETGDVIPLCLQKSVNTLIAVFGVLKAGAAFTPLDPKN 1638
Query: 545 PQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKK 604
P + + + DV+ ATLV+++ S + +V++ M L
Sbjct: 1639 PPARNEFI-----VSDVA-ATLVITDSHNASRFASF-SGDVINMDQIEMRLQDKSTATLV 1691
Query: 605 LPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACEL 653
+P + T + LAY+ ++ +TG+ G+++SH AV + MK AC +
Sbjct: 1692 IPEL----TPDNLAYIIYTSGSTGLPKGVQVSHRAVAASMEGMKEACNV 1736
>UniRef50_UPI0001597892 Cluster: NrsF; n=1; Bacillus
amyloliquefaciens FZB42|Rep: NrsF - Bacillus
amyloliquefaciens FZB42
Length = 549
Score = 51.2 bits (117), Expect = 1e-04
Identities = 86/418 (20%), Positives = 165/418 (39%), Gaps = 26/418 (6%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPH 544
++ A+L +K+ ++ +L +KG + D + + I F+ C+ G +P+ + +
Sbjct: 32 ISYAQLFEKSRKVLGVLQKKG-LRKKDELIIQIEDNEQFIKVFWACILGGIIPIPLSVGY 90
Query: 545 PQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKK 604
+ H + I + +S+Q + L K A S ++ D++
Sbjct: 91 NEE-HKQ--KILRIWSILNNPYCISDQRTLHSLE-KVADAETYSSIVKQSIYLDEIKNSN 146
Query: 605 LPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIALCLD 664
+P E +A++ FS TTG G+ ++H + + ++ A E S +
Sbjct: 147 EVGELISPKPEEIAFIQFSSGTTGDPKGVILTHKNLITNISALNEAWETSKSDSSLSWMP 206
Query: 665 PYCGLGFALWCLSSIYSGHHSILIPPSEVEVNPALWLSAVSQYKVRDTFC-SYGVMELCT 723
+G L+S Y +IP S P LWL Q++V + ++G
Sbjct: 207 LTHDMGLIAIHLASTYKKIQQYIIPTSVFIRRPTLWLLKTHQHRVTQLYSPNFGY----- 261
Query: 724 KGLGSSVNQLKSKGINLACVRTCVVVAEERPRINLTNSFSKLFSALGLSPRAVSTSFG-C 782
K L + + + +L CVR AE +L F + GL ++T +G
Sbjct: 262 KFLLDNYKKNQIYNWDLTCVRLLANGAEP-ISTSLCQRFLEEMKQFGLKYETLNTVYGLA 320
Query: 783 RVNIAICL-QGASSPEPSTVYVDLRALRNDRVSLVERGSPHSLCLMESGKLLPGVKVITA 841
+A+ + + +S P T+ + + VE + +E G P V+ +
Sbjct: 321 EATVAVSVPKLGNSFVPVTLNREALEVGQKIQKTVE--EKKGITFVEVG---PAVRHCSF 375
Query: 842 N--PETKGQCGDSHLGEIWVQSPHNASGYFTIYGDESDYADHFSAQ--LVTGNTGEVY 895
D +G + ++ + SGY Y +ES D +A L TG+ G ++
Sbjct: 376 RICDSNNYVLDDDFIGHVQIKGENVTSGY---YNNESATKDAITADGWLNTGDLGFIH 430
>UniRef50_Q0TDD6 Cluster: AMP-dependent synthetase; n=19;
Enterobacteriaceae|Rep: AMP-dependent synthetase -
Escherichia coli O6:K15:H31 (strain 536 / UPEC)
Length = 573
Score = 51.2 bits (117), Expect = 1e-04
Identities = 49/215 (22%), Positives = 82/215 (38%), Gaps = 7/215 (3%)
Query: 17 GEHMVCVLDFKRETGLWHAVLASVLNGMHVIFIPYALMKVSPASWMHMITKHRASIAIVK 76
G+ V L F + GL +L V + V ++ + P W+ +I+K+R ++++
Sbjct: 215 GDRCVSWLPFYHDMGLVGFLLTPVATQLSVDYLRTQDFAMRPLQWLKLISKNRGTVSVAP 274
Query: 77 --SRDLHWGLLATRDHKEISLSSLRMLLVADGANPWSLSSCDQFLSVFQSKGVRGDAICP 134
+L + +D E+ LS R+ + GA P S QF F+ P
Sbjct: 275 PFGYELCQRRVNEKDLAELDLSCWRVAGI--GAEPISAEQLHQFAECFRQVNFDDKTFMP 332
Query: 135 CACSSESMTVCIXXXXXXXXXXXXXVLSMSGLSYGVVRVDAENSLTSLTLQDCGQVMPSC 194
C +E+ + V DAE S T +CG+ +P
Sbjct: 333 CYGLAENALAVSFSDEASGVVVNEVDRDILEYQGKAVAPDAETRAVS-TFVNCGKALPEH 391
Query: 195 VIVVVKMEGPAYLCKTDEVGEICVLSGATGSGYWG 229
I + G + VG IC+ + SGY+G
Sbjct: 392 GIEIRNEAGIPVAERV--VGHICISGPSLMSGYFG 424
>UniRef50_Q0RMQ4 Cluster: Putative non-ribosomal peptide synthetase;
n=1; Frankia alni ACN14a|Rep: Putative non-ribosomal
peptide synthetase - Frankia alni (strain ACN14a)
Length = 2632
Score = 51.2 bits (117), Expect = 1e-04
Identities = 52/207 (25%), Positives = 93/207 (44%), Gaps = 17/207 (8%)
Query: 455 ISQILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVA 514
+ ++LR +A T D A A +LT EL +A R+ ++L E+G + VA
Sbjct: 461 VPELLRAQALRTPD------ATAVVAGDTMLTYRELDVRASRLASVLRERG-IGPDVLVA 513
Query: 515 LIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVI 574
+ P DL+ A G L G + I P +P + +++ + +VL++ +
Sbjct: 514 VALPRSADLVVALLGVLRAGGAYLPIDPAYPA------ARIELLLTAGEPAMVLTSGAGA 567
Query: 575 KLLRSKEASNVLDSKAWPMTLDTDDMPKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIK 634
L A + + + + LD + P E LAY+ F+ +TG G+
Sbjct: 568 ADL---PAHGLPELRLDELRLDEPGFAEAGAAAQGPHPQPENLAYVMFTSGSTGTPRGVA 624
Query: 635 MSHAAVTSLCRSMKIACELYP-SRHIA 660
++HA+V + R ++ A + P SR +A
Sbjct: 625 VTHASVVNGVRELRRAVGVGPGSRMLA 651
Score = 43.6 bits (98), Expect = 0.029
Identities = 44/170 (25%), Positives = 76/170 (44%), Gaps = 11/170 (6%)
Query: 480 AVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVT 539
A + LT A+L +A R+ L ++G V V +I P +++ A L GA +
Sbjct: 2061 AGDETLTYAQLDARARRLARELTDRG-VGPETVVVVILPRTANVVVALLAVLRAGAAYL- 2118
Query: 540 IRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDD 599
P HP H +R I+D ++ LV+ + LL S E ++ A T
Sbjct: 2119 --PVHPG--HAASGRLRQILDGARPHLVVVDADTRTLLPSAEIPRLVLDDAHTHREPTAA 2174
Query: 600 MPKKKLPIMYRAPTA--EMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSM 647
P +P P A + LAY+ ++ +TG+ G+ ++ V + R++
Sbjct: 2175 DP---VPATGARPAAGPDNLAYVVYTSGSTGVPKGVGITQRTVVNAVRAL 2221
>UniRef50_A6Y0W4 Cluster: Yersiniabactin non-ribosomal peptide
synthetase; n=3; Vibrionaceae|Rep: Yersiniabactin
non-ribosomal peptide synthetase - Vibrio cholerae RC385
Length = 2062
Score = 51.2 bits (117), Expect = 1e-04
Identities = 49/227 (21%), Positives = 100/227 (44%), Gaps = 19/227 (8%)
Query: 483 KVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRP 542
++L+ +L +A+R+ LL G + +G+HVA+ G+ I A L+ G V V I P
Sbjct: 582 QILSYNDLVSQAKRLAQTLLNAG-MQSGEHVAISMEKGVGQIVAVLAILHAGGVYVPIAP 640
Query: 543 PHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPK 602
P + T I + + +VL ++ + A+++ + L+T P
Sbjct: 641 NQPLSRRQT------IEESANVRIVLRCETCAQKFAWSSATHIDWQTHGDIALETS--PY 692
Query: 603 KKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIALC 662
+ P E AY+ ++ +TG G+ +SH + + C + + + I
Sbjct: 693 SRQP--------EQAAYIIYTSGSTGTPKGVVVSHQSALNTCLDINQRHRVCHTDRIFAV 744
Query: 663 LDPYCGLGFALWCLSSIYSGHHSILIPPSEVEVNPALWLSAVSQYKV 709
+ L +++ + + S ++++P + +P W S V+Q+ V
Sbjct: 745 AALHFDL--SVYDIFGVLSAGGALVLPKEQQTRDPMAWNSLVTQHSV 789
>UniRef50_Q8CJX2 Cluster: CDA peptide synthetase III; n=3;
Streptomyces|Rep: CDA peptide synthetase III -
Streptomyces coelicolor
Length = 2417
Score = 50.8 bits (116), Expect = 2e-04
Identities = 61/245 (24%), Positives = 109/245 (44%), Gaps = 19/245 (7%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPH 544
L+ AEL+ +A R+ LL+ +G VAL P +L A GA + + P H
Sbjct: 1562 LSYAELNARANRLARLLVARG-AGPERLVALALPRSAELPVAVLAVAKAGAAYLPLDPAH 1620
Query: 545 P-QNLHTTLPTVRMIVDVSKATLV--LSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMP 601
P + + TL + ++ A + L + V +LL +E + A +T D D +
Sbjct: 1621 PAERIAGTLDDAAPVALLTTAAVAAGLPDTDVPRLLLDEEPAAGGGEDAADLT-DADRLA 1679
Query: 602 KKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIAL 661
P++ P AY+ ++ TTG G+ ++H+ + +L ++ P +
Sbjct: 1680 ----PLLPGHP-----AYVIYTSGTTGRPKGVTVTHSGLPALLDIFTSQLDVVPGSRVLH 1730
Query: 662 CLDPYCGLGFALWCLS-SIYSGHHSILIPPSEVEVNPALWLSAVSQYKVRDTFCSYGVME 720
L P GF W L+ + +G +++ P V PAL AV +++V + V++
Sbjct: 1731 HLSPAFDGGF--WELAMGLLTGAALVVVEPGTVP-GPALAALAV-RHRVTHAAITPAVLQ 1786
Query: 721 LCTKG 725
L +G
Sbjct: 1787 LIPEG 1791
>UniRef50_A0QH53 Cluster: Linear gramicidin synthetase subunit D; n=4;
Bacteria|Rep: Linear gramicidin synthetase subunit D -
Mycobacterium avium (strain 104)
Length = 10421
Score = 50.8 bits (116), Expect = 2e-04
Identities = 45/171 (26%), Positives = 79/171 (46%), Gaps = 16/171 (9%)
Query: 483 KVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRP 542
+ T EL + + R+ +LL+ +G V G VAL+ P D I A L GA + I P
Sbjct: 7044 RTTTYRELDEASNRLAHLLIGRG-VGPGQAVALLLPRSADAIVAILAVLKTGAAYLPIDP 7102
Query: 543 PHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPK 602
P + ++D + T ++ ++ LR ++ + V+D ++ P
Sbjct: 7103 ALPA------ARIEFMLDDTAPTAAVTTAALAGPLRGRDLT-VVDIGDRALSRQ----PH 7151
Query: 603 KKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACEL 653
LP AP + +A++ ++ TTG+ G+ +SH VT L + + EL
Sbjct: 7152 TALP----APDPDHVAHIIYTSGTTGVPKGVAVSHHNVTRLFDAQAVGVEL 7198
Score = 41.9 bits (94), Expect = 0.090
Identities = 46/206 (22%), Positives = 86/206 (41%), Gaps = 19/206 (9%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPH 544
+T EL + A R+ + ++ G G+ VAL+FP + I A L GA + I P
Sbjct: 3449 MTYRELDEAANRLAHFMIHHG-AGPGERVALLFPRSAEAIVAILAALKSGAAYLPIDP-- 3505
Query: 545 PQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKK 604
LP R+ ++ A +++ + R + A P P
Sbjct: 3506 ------ALPAARVEFMLTDAAPIVAVTTAALAERLHGFDLTVIDVADPAVA---TQPATA 3556
Query: 605 LPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIALCLD 664
P+ P + +A++ ++ TTG+ G+ ++ V L ++I EL P R +
Sbjct: 3557 PPV----PDPDDVAHIIYTSGTTGVPKGVAVTQYNVAQLFDDLRIGIELSP-RQVWTQFH 3611
Query: 665 PYCGLGFALWCL-SSIYSGHHSILIP 689
Y F++W + ++ G +++P
Sbjct: 3612 SY-AFDFSVWEIWGALLHGGRLVVVP 3636
Score = 41.1 bits (92), Expect = 0.16
Identities = 41/163 (25%), Positives = 70/163 (42%), Gaps = 16/163 (9%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPH 544
LT +L + + R+ +LL G G VAL+F + + + L GA + I P
Sbjct: 486 LTYRQLDEASNRLAHLLAGLG-AGPGQSVALLFSRSAEAVASILAVLKTGAAYLPIDPAA 544
Query: 545 PQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKK 604
P+ + ++ +K LS + L + V+D P D P
Sbjct: 545 PET------RIGFMLADAKPVAALSTAELAGRLEA-HGMTVIDVND-PRI---QDRPATA 593
Query: 605 LPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSM 647
LP+ A+ +AY+ ++ TTG+ G+ ++H VT L S+
Sbjct: 594 LPVA----AADGVAYVIYTSGTTGVPKGVAVTHRNVTQLLGSL 632
Score = 40.7 bits (91), Expect = 0.21
Identities = 42/165 (25%), Positives = 70/165 (42%), Gaps = 20/165 (12%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPH 544
+T +L + + R+ + L G G VAL+F + + A L GA + I P
Sbjct: 4504 VTYRQLDEASNRLAHRLAAAG-AGPGQTVALLFSRSAEAVAAILAVLKTGAAYLPIDPSA 4562
Query: 545 PQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMT-LDTDDMPKK 603
PQ ++ +L + I + + E + L + P+T +D DD
Sbjct: 4563 PQ---------------TRVEFMLGDAEPIAAVTTAELAQRLAGR--PVTVVDVDDPGID 4605
Query: 604 KLP-IMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSM 647
LP P + +AYL ++ TTG G+ ++H VT L S+
Sbjct: 4606 TLPDTALPLPDPDGIAYLIYTSGTTGAPKGVAVTHHNVTQLLGSL 4650
>UniRef50_Q93H68 Cluster: Non-ribosomal peptide synthetase; n=1;
Streptomyces avermitilis|Rep: Non-ribosomal peptide
synthetase - Streptomyces avermitilis
Length = 1768
Score = 50.4 bits (115), Expect = 3e-04
Identities = 55/226 (24%), Positives = 98/226 (43%), Gaps = 20/226 (8%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPH 544
LT AEL +A R+ L E+G V D VA++ L+ A Y L GA + + P +
Sbjct: 296 LTYAELDARANRLARTLRERG-VGRDDLVAVLADRSPQLLVAVYAVLKAGAAYLPVDPGY 354
Query: 545 PQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRS-KEASNVLDSKAWPMTLDTDDMPKK 603
P + +R ++D S A LVLS L+ +E ++ D A+ ++
Sbjct: 355 P------VERIRYVLDDSAARLVLSTPRHRDLVHEGREVLDLTDESAYAKDSTAPEV--- 405
Query: 604 KLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIALCL 663
A LAY+ ++ +TG G+++ H +V + M+ A + S + +
Sbjct: 406 -------IGDARDLAYVIYTSGSTGNPKGVQIEHRSVVNRINWMQRAYPV-TSADVIMQK 457
Query: 664 DPYCGLGFALWCLSSIYSGHHSILIPPSEVEVNPALWLSAVSQYKV 709
P ++W L ++ +P E +P ++A+ +Y V
Sbjct: 458 TP-TSFDVSVWELFWWMFEGAAVCLPDPGAERDPEALVTAIERYGV 502
>UniRef50_A6LQ10 Cluster: Amino acid adenylation domain; n=1;
Clostridium beijerinckii NCIMB 8052|Rep: Amino acid
adenylation domain - Clostridium beijerinckii NCIMB 8052
Length = 4034
Score = 50.4 bits (115), Expect = 3e-04
Identities = 82/408 (20%), Positives = 156/408 (38%), Gaps = 28/408 (6%)
Query: 510 GDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLS 569
GD V D I + C+ G V V P N H + V + + + ++S
Sbjct: 58 GDEVLFQVEREEDFIYFSWACILGGMVSV---PLSCNNTHENIMQVSRVWKILQKPKLIS 114
Query: 570 NQ----SVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKKLPIMYRAPTAEMLAYLDFSVS 625
+ S++ +L ++ ++ D LD D + + + ++ A++ FS
Sbjct: 115 TKEQLKSIVDILNNENCGDIADEIKQNTLLDKDILVSNGIGEIACGDISDT-AFVVFSSG 173
Query: 626 TTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALW-CLSSIYSGHH 684
+TG GI +++ + SM ++ S + +G L+ L Y +H
Sbjct: 174 STGEPKGIVLTNEKILCAIESMSSHLDVNSSDVFLNWMPLTHVIGLVLFHVLPVAYDLNH 233
Query: 685 SILIPPSEVEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGI--NLAC 742
++ ++ NP LWL QYK +M G +N S I NL+
Sbjct: 234 VVMSKNLFIK-NPVLWLEKADQYKAT-------IMISPNIGFRQFLNCFDSNTINMNLSH 285
Query: 743 VRTCVVVAEERPRINLTNSFSKLFSALGLSPRAVSTSFGCRVNI--AICLQGASSPEPST 800
VRT +V AE +L+ F + S G+ +S +G + C + + +
Sbjct: 286 VRTIMVSAEPISG-DLSEQFMTVLSKFGIRKNVLSNLYGMSESCLGITCTLPSEDMKYNC 344
Query: 801 VYVDLRALRNDRVSLVERGSPHSLCLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQ 860
+ + A+ D++ + G + SG + + + +T GD +G + V
Sbjct: 345 LNRNFLAV-GDKIKYGQPGDEDCSIFVNSGTPIKDC-FVRISDDTGNILGDDCIGHVQVT 402
Query: 861 SPHNASGYFTIYGDESDYADHFSAQLVTGNTGEVYARTGYLGFLRRTE 908
+ + Y+T + L+TG+ G + G+L R +
Sbjct: 403 GKNIINNYYTEEATARSFTS--DGWLITGDIG--FLENGHLTITGRAK 446
Score = 40.7 bits (91), Expect = 0.21
Identities = 22/63 (34%), Positives = 33/63 (52%), Gaps = 1/63 (1%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPH 544
LT EL +K+ ++ N L EK + D+V +I ++ I G L GA V I P H
Sbjct: 3274 LTYKELDEKSNKVANFLKEKN-IGRNDYVGVIAERCIESIVNILGVLKAGAAYVPINPEH 3332
Query: 545 PQN 547
P++
Sbjct: 3333 PED 3335
Score = 38.7 bits (86), Expect = 0.84
Identities = 20/64 (31%), Positives = 34/64 (53%), Gaps = 1/64 (1%)
Query: 483 KVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRP 542
+ +T EL KK+ +I L E+G + GD+V ++ ++ I G L GA + + P
Sbjct: 2207 ETITYEELDKKSNQIAKYLNEQGVIR-GDYVGVLAYRKIETIVNILGVLKAGAAYIPLNP 2265
Query: 543 PHPQ 546
HP+
Sbjct: 2266 DHPE 2269
Score = 37.5 bits (83), Expect = 1.9
Identities = 19/63 (30%), Positives = 33/63 (52%), Gaps = 1/63 (1%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPH 544
+T EL KK+ +I L E G + GD++ ++ ++ I G L GA + + P H
Sbjct: 1148 ITYEELDKKSNQIAKCLNEHGVIR-GDYIGVLAYRRIETIVNILGILKAGAAYIPLNPDH 1206
Query: 545 PQN 547
P++
Sbjct: 1207 PED 1209
>UniRef50_Q5SBL2 Cluster: Equisetin synthetase; n=1; Fusarium
heterosporum|Rep: Equisetin synthetase - Fusarium
heterosporum
Length = 3953
Score = 50.4 bits (115), Expect = 3e-04
Identities = 48/222 (21%), Positives = 91/222 (40%), Gaps = 17/222 (7%)
Query: 478 KGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVP 537
K + LT ++ ++ + I ++ KG N GD V + PG D IC+ L +GA
Sbjct: 3017 KVGTNTALTYEDMGRRVDAIAQYMVSKGVAN-GDVVGIFQAPGTDWICSMLAILRIGATY 3075
Query: 538 VTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASN--VLDSKAWPMTL 595
+ P +L ++ ++ V ++K ++L + S ++ L+S N V+D A P
Sbjct: 3076 L------PLDLRNSIHRLQDSVRIAKPDMLLVDPSTLETLKSITTGNAEVMDISAIP--- 3126
Query: 596 DTDDMPKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYP 655
+ A + A + F+ +TG GI++ H+ + + C + P
Sbjct: 3127 -----HNTSVAHQVSAARGQDTAVILFTSGSTGEPKGIRIKHSNLVAQNEGFSKQCNISP 3181
Query: 656 SRHIALCLDPYCGLGFALWCLSSIYSGHHSILIPPSEVEVNP 697
+ F+L + + I PSE+ +P
Sbjct: 3182 GEAFNVLQQSAFSFDFSLEQIFVALCNGGCLHIVPSEIRGDP 3223
>UniRef50_Q9Z4X6 Cluster: CDA peptide synthetase I; n=4; cellular
organisms|Rep: CDA peptide synthetase I - Streptomyces
coelicolor
Length = 7463
Score = 50.0 bits (114), Expect = 3e-04
Identities = 52/218 (23%), Positives = 84/218 (38%), Gaps = 14/218 (6%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPH 544
LT EL+++A R+ LL +G VA+ P DL+ + GA + + P H
Sbjct: 2784 LTYGELNERANRLARALLARG-AGPERFVAVALPRSADLVLSALAAFKAGAAYLPVDPAH 2842
Query: 545 PQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDT---DDMP 601
P T L + D + +V ++ L + +LD+ TL D+
Sbjct: 2843 PAERITHL-----VSDAAPTLIVTTSALAASLPDTGTPVLLLDTPETAATLAALPGHDVT 2897
Query: 602 KKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIAL 661
P+ R E AY+ ++ TTG G+ ++H + L C P I
Sbjct: 2898 DADRPVPLRP---EHPAYMIYTSGTTGRPKGVVVTHTGLPGLLDIFTRDCAAGPGSRILQ 2954
Query: 662 CLDPYCGLGFALWCLSSIYSGHHSILIPPSEVEVNPAL 699
L P F W L+ ++++ P E P L
Sbjct: 2955 HLSPSFDASF--WELAMGLLTGATLVVAPPETTPGPEL 2990
Score = 41.5 bits (93), Expect = 0.12
Identities = 46/177 (25%), Positives = 73/177 (41%), Gaps = 11/177 (6%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPH 544
LT AEL +AER+ L +G VA+ +L+ A L GA V + P +
Sbjct: 496 LTYAELDARAERLAGALTARG-AGPERFVAVAVERSAELVVALLAVLKSGAAYVPVDPGY 554
Query: 545 PQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVL--DSKAWPMTLDTDDMPK 602
P + + I+ + A LVL+ + + L +L + A T P
Sbjct: 555 PAD------RIAHILRDAGAMLVLTTRDTAERLPGDGTPRLLLDEPAAAGTTAAGAPAPP 608
Query: 603 KKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHI 659
LP AP AY+ ++ +TG G+ +SH A+ + M+ L PS +
Sbjct: 609 GTLPRALPAPGHP--AYVIYTSGSTGRPKGVVISHRAIVNRLAWMQDTYGLEPSDRV 663
>UniRef50_Q9R686 Cluster: Gramicidin S synthetase 2, GRSB; n=1;
Bacillus subtilis|Rep: Gramicidin S synthetase 2, GRSB -
Bacillus subtilis
Length = 1876
Score = 50.0 bits (114), Expect = 3e-04
Identities = 67/257 (26%), Positives = 113/257 (43%), Gaps = 28/257 (10%)
Query: 489 ELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNL 548
EL+ KA ++ +L EKG V VA++ L++I + L G V I P +PQ
Sbjct: 1499 ELNIKANQLARVLREKG-VTPNHPVAIMTERSLEMIVGIFSILKAGGAYVPIDPAYPQE- 1556
Query: 549 HTTLPTVRMIVDVSKATLVLSNQSVI-KLLRSKEASNVLDSKAWPMTLDTDDMPKKKLPI 607
++ +++ S A L+L+ V+ KL E ++ D + + +D LP
Sbjct: 1557 -----RIQYLLEDSGAALLLTQSHVLNKLPVDIEWLDLTDEQNY-----VED--GTNLPF 1604
Query: 608 MYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIALCLDPYC 667
M ++ LAY+ ++ TTG G+ + H ++ + + K E P AL + +
Sbjct: 1605 MNQSTD---LAYIIYTSGTTGKPKGVMIEHQSIINCLQWRKEEYEFGPG-DTALQVFSFA 1660
Query: 668 GLGFALWCLSSIYSGHHSILIPPSEVEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLG 727
GF + I +G S+L P E +P ++ ++ YGV L + L
Sbjct: 1661 FDGFVASLFAPILAGATSVL-PKEEEAKDPVALKKLIASEEITH---YYGVPSLFSAILD 1716
Query: 728 SSVNQLKSKGI-NLACV 743
S SK + NL CV
Sbjct: 1717 VS----SSKDLQNLRCV 1729
Score = 48.0 bits (109), Expect = 0.001
Identities = 48/223 (21%), Positives = 99/223 (44%), Gaps = 19/223 (8%)
Query: 489 ELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNL 548
EL+ KA ++ +L +KG V V ++ LD+I G L G V I +PQ
Sbjct: 1109 ELNAKANQLARVLRQKG-VQPNSMVGIMVDRSLDMIVGMLGVLKAGGAYVPIDIDYPQE- 1166
Query: 549 HTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKKLPIM 608
+ +++ S A L+L+ Q + + + LD + W + + ++ P
Sbjct: 1167 -----RISYMMEDSGAALLLTQQKLTQQIAFSGDILYLDQEEW-LHEEASNLEPIARP-- 1218
Query: 609 YRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACEL--YPSRHIALCLDPY 666
+AY+ ++ TTG G+ + H + ++ + K A L +P R + + +
Sbjct: 1219 ------HYIAYIIYTSGTTGKPKGVMIEHQSYVNVAMAWKDAYRLDTFPVRLLQMASFAF 1272
Query: 667 CGLGFALWCLSSIYSGHHSILIPPSEVEVNPALWLSAVSQYKV 709
A ++ +G +++ P+EV+++PA + + +Y +
Sbjct: 1273 AFDVSAGDFARALLTG-GQLIVCPNEVKMDPASLYAIIKKYDI 1314
Score = 39.5 bits (88), Expect = 0.48
Identities = 31/155 (20%), Positives = 72/155 (46%), Gaps = 13/155 (8%)
Query: 489 ELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNL 548
EL+ KA ++ + +EKG + V ++ +DL L G V I +P+
Sbjct: 3 ELNVKANQLARIFIEKG-IGKDTLVGIMMEKSIDLFIGILAVLKAGGAYVPIDIEYPKE- 60
Query: 549 HTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKKLPIM 608
++ I+D S+A ++L+ + ++ L+ + + + ++ + D + ++ +
Sbjct: 61 -----RIQYILDDSQARMLLTQKHLVHLIHNIQFNGQVE------IFEEDTIKIREGTNL 109
Query: 609 YRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSL 643
+ + LAY+ ++ TTG G + H +++L
Sbjct: 110 HVPSKSTDLAYVIYTSGTTGNPKGTMLEHKGISNL 144
>UniRef50_Q0B1F7 Cluster: Amino acid adenylation domain; n=2;
Bacteria|Rep: Amino acid adenylation domain -
Burkholderia cepacia (strain ATCC 53795 / AMMD)
Length = 3176
Score = 50.0 bits (114), Expect = 3e-04
Identities = 44/158 (27%), Positives = 74/158 (46%), Gaps = 13/158 (8%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPH 544
LT AEL+ +A R+ + L+E G V V + LD++ A L G V + P +
Sbjct: 1322 LTYAELNLRANRLAHRLIELG-VAPDVLVGVAMERSLDMVVALLAILKAGGAYVPVDPEY 1380
Query: 545 PQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKK 604
P VR ++D ++ +L+ Q ++ L +A ++ + TLD D P
Sbjct: 1381 PAE------RVRFMIDHAQLRWLLTQQHLLDALPDTDARVIVVDRD---TLDLDAAPASN 1431
Query: 605 LPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTS 642
P A + E LAY+ ++ +TG G +H A+T+
Sbjct: 1432 -PAP--ALSGENLAYMIYTSGSTGRPKGALNTHRAITN 1466
>UniRef50_O30408 Cluster: Tyrocidine synthetase 2 (Tyrocidine
synthetase II) [Includes: ATP- dependent proline
adenylase (ProA) (Proline activase); ATP-dependent
phenylalanine adenylase (PheA) (Phenylalanine activase);
ATP-dependent D-phenylalanine adenylase (D-PheA)
(D-phenylalanine activase); Phenylalanine racemase
[ATP-hydrolyzing] (EC 5.1.1.11)]; n=5;
Paenibacillaceae|Rep: Tyrocidine synthetase 2 (Tyrocidine
synthetase II) [Includes: ATP- dependent proline
adenylase (ProA) (Proline activase); ATP-dependent
phenylalanine adenylase (PheA) (Phenylalanine activase);
ATP-dependent D-phenylalanine adenylase (D-PheA)
(D-phenylalanine activase); Phenylalanine racemase
[ATP-hydrolyzing] (EC 5.1.1.11)] - Brevibacillus
parabrevis
Length = 3587
Score = 50.0 bits (114), Expect = 3e-04
Identities = 53/223 (23%), Positives = 100/223 (44%), Gaps = 27/223 (12%)
Query: 425 NLVQGNRLASAQGRDMGYTDDSDAARKY---QFISQILRWRAQSTSDHVIFTLLNAKGAV 481
N +Q + +A + M +D R+Y Q I Q+ A+ +H
Sbjct: 2513 NELQEIEMLTAAEKQMLLVAFNDTHREYRADQTIQQLFEELAEKMPEHTALVF------E 2566
Query: 482 SKVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIR 541
K ++ EL+++A ++ +L EKG V VAL+ +++ A L G + +
Sbjct: 2567 EKRMSFRELNERANQLAAVLREKG-VGPAQIVALLVERSAEMVIATLATLKAGGAFLPVD 2625
Query: 542 PPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVI-KLLRSKEASNVLDSKAWPMTLDTDDM 600
P +P+ +R +++ S+A LV+++ ++ K+ E +V D ++ TD++
Sbjct: 2626 PDYPEE------RIRYMLEDSQAKLVVTHAHLLHKVSSQSEVVDVDDPGSY--ATQTDNL 2677
Query: 601 PKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSL 643
P A T LAY+ ++ TTG G+ + H V +L
Sbjct: 2678 PC--------ANTPSDLAYIIYTSGTTGKPKGVMLEHKGVANL 2712
Score = 37.5 bits (83), Expect = 1.9
Identities = 51/212 (24%), Positives = 87/212 (41%), Gaps = 18/212 (8%)
Query: 483 KVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRP 542
K LT EL+++A ++ + L KG V V ++ L++ L G V I P
Sbjct: 1531 KRLTYRELNERANQLAHTLRAKG-VQAEQSVGIMAQRSLEMAIGIIAILKAGGAYVPIDP 1589
Query: 543 PHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPK 602
+P M+ D + LVL+ Q + + + + LD + + T+++
Sbjct: 1590 DYPNER-----IAYMLEDCRR--LVLTQQQLAEKMTANVECLYLDEEG-SYSPQTENIE- 1640
Query: 603 KKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIALC 662
PI TA LAY+ ++ TTG G+ + H + + + L L
Sbjct: 1641 ---PIH----TAADLAYIIYTSGTTGRPKGVMVEHRGIVNSVTWNRDEFALSVRDSGTLS 1693
Query: 663 LDPYCGLGFALWCLSSIYSGHHSILIPPSEVE 694
L + FAL + I SG +L+P E +
Sbjct: 1694 LS-FAFDAFALTFFTLIVSGSTVVLMPDHEAK 1724
Score = 35.5 bits (78), Expect = 7.8
Identities = 21/61 (34%), Positives = 29/61 (47%), Gaps = 1/61 (1%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPH 544
LT EL +K+ ++ L +KG + TG V + LD+I G L G V I P
Sbjct: 493 LTYRELDEKSNQLARFLRKKG-IGTGSLVGTLLDRSLDMIVGILGVLKAGGAFVPIDPEL 551
Query: 545 P 545
P
Sbjct: 552 P 552
>UniRef50_A3P7D6 Cluster: Non-ribosomal peptide synthase; n=34;
Bacteria|Rep: Non-ribosomal peptide synthase -
Burkholderia pseudomallei (strain 1106a)
Length = 4468
Score = 49.6 bits (113), Expect = 4e-04
Identities = 53/221 (23%), Positives = 99/221 (44%), Gaps = 18/221 (8%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPH 544
L+ AEL+ +A R+ + L +G V G VAL G++++ L G V + P +
Sbjct: 1670 LSYAELNARANRLAHYLQGRG-VGPGRLVALCAERGIEMVVGLLAILKAGGAYVPLDPAY 1728
Query: 545 PQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKK 604
+ +R IV+ S+ LVL++ + A LD + L+TD + ++
Sbjct: 1729 ASD------RLRGIVEDSQPALVLADAV------GRAALGELDGALPVIDLETDALRWRE 1776
Query: 605 LPIMYRAPTAEM---LAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIAL 661
+P ++ LAY+ ++ +TG G+ + HA V L + + A + R +
Sbjct: 1777 MPATNPEVASQHVHHLAYVIYTSGSTGRPKGVMVEHAQVVRLFGATQ-AWFGFDERDVWT 1835
Query: 662 CLDPYCGLGFALWCLSSIYSGHHSILIPPSEVEVNPALWLS 702
Y G F++W + ++I P+EV P+ + +
Sbjct: 1836 LFHSY-GFDFSVWEMWGALLHGGRLVIVPTEVTRTPSAFFA 1875
Score = 45.6 bits (103), Expect = 0.007
Identities = 44/163 (26%), Positives = 73/163 (44%), Gaps = 16/163 (9%)
Query: 488 AELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPHP-Q 546
AEL+++A R+ L +G + VA+ G+D++ A L G V + P +P +
Sbjct: 2809 AELNRRANRLARHLSARG-LQPDQRVAICIDRGIDMVVAMLAVLKAGGAYVPLDPAYPSE 2867
Query: 547 NLHTTLPTVRMIVDVSKATLVLSNQS--VIKLLRSKEASNVLDSK----AWPMTLDTDDM 600
L L + ++ A L S Q+ V+ L R ++D + AW D DD
Sbjct: 2868 RLDYLLRDCAPVALLTHARLGASMQTRLVLALARLDTGCALIDLESDAGAWRHERD-DDP 2926
Query: 601 PKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSL 643
P L T LAY+ ++ +TG G+ + H +V +L
Sbjct: 2927 PPSGL-------TPRHLAYVIYTSGSTGQPKGVMVEHRSVCNL 2962
Score = 41.9 bits (94), Expect = 0.090
Identities = 46/180 (25%), Positives = 77/180 (42%), Gaps = 10/180 (5%)
Query: 483 KVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRP 542
+ LT AEL++ A R+ + L +G V GD VAL +L+ L G V + P
Sbjct: 570 RALTYAELNRCANRLAHYLRARG-VRGGDRVALYARRSPELLIGMLATLKAGGAYVPLDP 628
Query: 543 PHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIK--LLRSKEASNVLDSKAWPMTLDTDDM 600
+P T +++D S +VL + + L+R + +LD A
Sbjct: 629 GYPAERLT-----HILLD-SAPVVVLRDAAASDDVLVRLNAGTLILDLHADDERWSAQPS 682
Query: 601 PKKKLPIMYRAPT-AEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHI 659
KL + A LAY+ ++ +TG G+ + HA+V + ++ EL S +
Sbjct: 683 GNLKLCGSHEPDVGARRLAYVIYTSGSTGAPKGVMVEHASVVNQIGALTEYLELDASDRV 742
>UniRef50_A1CFN0 Cluster: Nonribosomal peptide synthase, putative;
n=3; cellular organisms|Rep: Nonribosomal peptide
synthase, putative - Aspergillus clavatus
Length = 6199
Score = 49.6 bits (113), Expect = 4e-04
Identities = 45/158 (28%), Positives = 73/158 (46%), Gaps = 12/158 (7%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPH 544
L+ A+L KK ++ +L+ R+ D V + F I A G L GA V + P H
Sbjct: 3986 LSYAQLDKKTTQLARVLVSM-RLGPDDLVPICFDKSSWAIVAMLGILKAGAGFVPLDPAH 4044
Query: 545 PQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKK 604
P + I+ + ++L L + S K + + ++ S M LD+DD
Sbjct: 4045 PPE------RLASIIAQTSSSLALVSLSTSKRVVDLVPNILVISSGSNMWLDSDD--SLT 4096
Query: 605 LPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTS 642
LP APT +AY F+ +TG G+ + H+AV++
Sbjct: 4097 LPA---APTTRNIAYTLFTSGSTGTPKGVVVEHSAVST 4131
>UniRef50_Q0VMQ7 Cluster: Peptide synthetase, putative; n=1;
Alcanivorax borkumensis SK2|Rep: Peptide synthetase,
putative - Alcanivorax borkumensis (strain SK2 / ATCC
700651 / DSM 11573)
Length = 3600
Score = 49.2 bits (112), Expect = 6e-04
Identities = 36/154 (23%), Positives = 75/154 (48%), Gaps = 14/154 (9%)
Query: 488 AELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQN 547
AEL ++ ++ L+ +G V V + F G+ ++ AF + G + + P +P +
Sbjct: 499 AELEARSNQLARYLMGQG-VKADQVVGVSFERGVTMVEAFIAVMKAGGAFLPLDPGYPAD 557
Query: 548 LHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKKLPI 607
+R +++ S A+L+L++ ++ L S EA N P+ +D + I
Sbjct: 558 ------RLRYMLEDSGASLLLTSSDLVDTLPSVEAVN-------PIAVDELSLDDFAYGI 604
Query: 608 MYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVT 641
+ P + LAY+ ++ +TG G+ ++HA ++
Sbjct: 605 LNEEPHPDQLAYVIYTSGSTGKPKGVSLTHAGLS 638
Score = 39.9 bits (89), Expect = 0.36
Identities = 39/155 (25%), Positives = 76/155 (49%), Gaps = 16/155 (10%)
Query: 488 AELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQN 547
AEL ++ ++ L+ +G V V + F G+ ++ AF + G + + P +P++
Sbjct: 1980 AELDARSNQLARYLMGQG-VKADQVVGVSFERGVTMVEAFIAVMKAGGAFLPLDPGYPKD 2038
Query: 548 -LHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKKLP 606
LH M+ D S A L+L++ ++I +L E + V ++L+ D P L
Sbjct: 2039 RLHY------MLKD-SGARLLLTSSALIGVL--PEVATVAPVAVDRLSLN--DFPANALN 2087
Query: 607 IMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVT 641
P + LAY+ ++ +TG G+ ++HA ++
Sbjct: 2088 ---NEPHPDQLAYVIYTSGSTGKPKGVSLTHAGLS 2119
>UniRef50_Q0PH94 Cluster: MassC; n=1; Pseudomonas fluorescens|Rep:
MassC - Pseudomonas fluorescens
Length = 3774
Score = 49.2 bits (112), Expect = 6e-04
Identities = 49/178 (27%), Positives = 81/178 (45%), Gaps = 19/178 (10%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPH 544
LT AEL+++A + + LL G V D VA++ GLD + L GA V + P H
Sbjct: 588 LTYAELNQQANLLAHHLLALG-VKPDDRVAIVARRGLDTLAGLLAILKAGAGYVPVDPSH 646
Query: 545 P-QNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNV-LDSKAWPMTLDTDDMPK 602
P + LH ++ S VL+ ++++ L + + + LD W ++
Sbjct: 647 PAERLH-------YLLSDSAPVAVLTQHALLERLPALDVPVINLDRFTWQHHSASN---- 695
Query: 603 KKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIA 660
P + PT LAY+ ++ +TG+ G+ + H V +L A +L RH A
Sbjct: 696 ---PTIAVGPT--NLAYVIYTSGSTGLPKGVMVEHHTVANLVDWHCSAFDLRAGRHTA 748
>UniRef50_A7IZW2 Cluster: OciB; n=1; Planktothrix agardhii NIVA-CYA
116|Rep: OciB - Planktothrix agardhii NIVA-CYA 116
Length = 4728
Score = 49.2 bits (112), Expect = 6e-04
Identities = 44/189 (23%), Positives = 86/189 (45%), Gaps = 19/189 (10%)
Query: 455 ISQILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVA 514
I Q+ +A+ T D + N + LT AEL+ +A ++ + L + G V + V
Sbjct: 2622 IHQLFEEQAERTPDAIAVVFENQQ------LTYAELNDRANQLAHYLRKLG-VKPDELVG 2674
Query: 515 LIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVI 574
+ LD+I L VG V I P +PQ + ++ ++ ++L+ +S+
Sbjct: 2675 ICLERSLDMIVGLLAILKVGGAYVPIDPDYPQE------RISFMLQDTQVKIILTCESLQ 2728
Query: 575 KLLRSKEASNVLDSKAWPMTLDTDDMPKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIK 634
L++ + + K W + + L + +A+ LAY+ ++ +TG+ G+
Sbjct: 2729 NSLQNHQTIVICLDKDW------QQINQASLENLNSTVSADNLAYVIYTSGSTGIPKGVI 2782
Query: 635 MSHAAVTSL 643
++H AV L
Sbjct: 2783 VTHQAVNRL 2791
Score = 45.6 bits (103), Expect = 0.007
Identities = 45/207 (21%), Positives = 90/207 (43%), Gaps = 23/207 (11%)
Query: 455 ISQILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVA 514
I Q++ +A+ T D + N + LT A+L+ +A ++ + L G V T V
Sbjct: 3687 IHQLIEEQAERTPDAIAVVFENQQ------LTYAQLNNRANQLAHYLRSLG-VETEVIVG 3739
Query: 515 LIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVI 574
L L++I G L G + + P +PQ ++ +++ S+ L+L+ S+I
Sbjct: 3740 LCVERSLEMIVTLIGILKAGGAYLPLDPEYPQ------ARLQFMLEDSQIPLLLTQHSLI 3793
Query: 575 KLLRSKEASNVLDSKAWPMTLDT--DDMPKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAG 632
L + + + + W T D++ K P LA + ++ +TG G
Sbjct: 3794 DKLPNHQGQTLFLEEIWEKTAQPSQDNLTAKVTP--------SNLANVIYTSGSTGKPKG 3845
Query: 633 IKMSHAAVTSLCRSMKIACELYPSRHI 659
+ + H + +L ++ ++PS +
Sbjct: 3846 VMVEHKGLCNLAQAQIETLGVHPSSRV 3872
>UniRef50_A4XWA8 Cluster: Amino acid adenylation domain; n=1;
Pseudomonas mendocina ymp|Rep: Amino acid adenylation
domain - Pseudomonas mendocina ymp
Length = 5328
Score = 49.2 bits (112), Expect = 6e-04
Identities = 41/169 (24%), Positives = 75/169 (44%), Gaps = 14/169 (8%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPH 544
L+ AEL +A + + L+ +G V V + G++L A L G V + P +
Sbjct: 4083 LSFAELEARANCLAHQLIARG-VGAEVRVGVALERGIELFVALLAVLKAGGAYVPLDPDY 4141
Query: 545 PQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKK 604
P +R +++ + L+LS+Q+ + L VLD P+ + P+
Sbjct: 4142 PGE------RLRYMLEDAGVKLLLSHQAALPRLPEVAGIEVLDLDHLPLNDQPEQAPEVN 4195
Query: 605 LPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACEL 653
+ E LAYL ++ +TG G+ ++H A+ C+++ EL
Sbjct: 4196 IH-------HEQLAYLIYTSGSTGKPKGVAVAHGAIAMHCQAIGERYEL 4237
Score = 47.6 bits (108), Expect = 0.002
Identities = 43/169 (25%), Positives = 77/169 (45%), Gaps = 14/169 (8%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPH 544
L+ AEL +A R+ + L+ +G V V + G++L L G V + P +
Sbjct: 1996 LSFAELEARANRVAHQLIARG-VGAEVRVGVALERGIELFVVLLAVLKTGGAYVPLDPDY 2054
Query: 545 PQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKK 604
P +R +++ + L+LS+Q + L + V D L +D P++
Sbjct: 2055 PGE------RLRYMLEDAGVKLLLSHQPALPRLPAVAGIEVFDLDH----LQLNDQPEQA 2104
Query: 605 LPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACEL 653
P + P E LAYL ++ +TG G+ ++H A+ C+++ EL
Sbjct: 2105 -PEVDIHP--EQLAYLIYTSGSTGKPKGVAVAHGAIALHCQAIGERYEL 2150
Score = 40.7 bits (91), Expect = 0.21
Identities = 42/169 (24%), Positives = 76/169 (44%), Gaps = 14/169 (8%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPH 544
L+ AEL +A ++ + L + G V+ V + ++++ A Y L G V + P +
Sbjct: 3043 LSYAELDLRANQLAHHLQKLG-VSRDSLVGVAALRSVEMVVALYAILKAGGAYVPMDPEY 3101
Query: 545 PQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKK 604
P +R +++ S +L+LS+ +VI L VL+ ++ + P+
Sbjct: 3102 PAE------RLRYMLEDSGVSLLLSHDAVIDSLPQVSGVQVLNLDHLDLSQEPQTAPEVD 3155
Query: 605 LPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACEL 653
+ E LAYL ++ +TG G SHAA+ + M+ A L
Sbjct: 3156 IH-------PEQLAYLIYTSGSTGKPKGAGNSHAALYNRLAWMQQAYHL 3197
Score = 39.5 bits (88), Expect = 0.48
Identities = 42/169 (24%), Positives = 75/169 (44%), Gaps = 14/169 (8%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPH 544
L+ AEL +A ++ + L + G V V + ++++ A Y L G V + P +
Sbjct: 529 LSYAELDLRANQLAHHLQKLG-VTRDSLVGVAALRSVEMVVALYAILKAGGAYVPMDPEY 587
Query: 545 PQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKK 604
P +R +++ S +L+LS+ +VI L VL+ ++ + P+
Sbjct: 588 PAE------RLRYMLEDSGVSLLLSHDAVIDGLPQVSGVQVLNLDHLDLSQEPQTAPEVD 641
Query: 605 LPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACEL 653
+ E LAYL ++ +TG G SHAA+ + M+ A L
Sbjct: 642 IH-------PEQLAYLIYTSGSTGKPKGAGNSHAALYNRLAWMQQAYHL 683
>UniRef50_A0ZF82 Cluster: Non-ribosomal peptide synthase; n=2;
Nostocaceae|Rep: Non-ribosomal peptide synthase -
Nodularia spumigena CCY 9414
Length = 1394
Score = 49.2 bits (112), Expect = 6e-04
Identities = 40/181 (22%), Positives = 83/181 (45%), Gaps = 18/181 (9%)
Query: 482 SKVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIR 541
S+ LT +L++KA ++ + L++ + V + L++I G L G V I
Sbjct: 563 SQQLTYQQLNQKANQLAHYLIQNYPIQPDTLVGICVERSLEMIIGVLGVLKAGGAYVPID 622
Query: 542 PPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLL---RSKEASNVLDSKAWPMTLDTD 598
P +PQ ++ +++ S +++L+ +++ L K + LD +A+ L
Sbjct: 623 PNYPQE------RIKFLLEDSGVSVLLTQSFILEQLPITEQKYQAICLDKEAFAEELT-- 674
Query: 599 DMPKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRH 658
D P K+ T E LAY+ ++ +TG G+ + H + +L ++ ++ P
Sbjct: 675 DNPSPKI-------TPENLAYVIYTSGSTGRPKGVMIEHGGLVNLTLAVNQVLQIQPQSR 727
Query: 659 I 659
+
Sbjct: 728 L 728
>UniRef50_Q0UX94 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 1001
Score = 49.2 bits (112), Expect = 6e-04
Identities = 50/236 (21%), Positives = 97/236 (41%), Gaps = 9/236 (3%)
Query: 481 VSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTI 540
VS +T +L ++AE L G + L F + + F+ + G VP +
Sbjct: 61 VSDFVTYVDLLRQAETNATKLRAHGTIKQKQCTVLYFNTHRENVIWFWSVVAAGGVPALL 120
Query: 541 RPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDM 600
P N T + + + +L+++ + K R + +++ T ++
Sbjct: 121 SPLS-SNDATLAGELDNVSKLFNGPTILTSKRLAKPFRMVPTLTTITAESVATTKSNENG 179
Query: 601 PKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIA 660
K PI + LA + F+ +TG G++ +HA L S K+ C+ +
Sbjct: 180 AWK--PIDGGFDHEDELATVLFTSGSTGFAKGVEYTHA---QLVTSSKLKCDFHLMDSSK 234
Query: 661 LCLDPYCGLGFALWC---LSSIYSGHHSILIPPSEVEVNPALWLSAVSQYKVRDTF 713
L A C L ++Y+G + +++P + +PA + A+S Y++ TF
Sbjct: 235 TFLSWVSFDHSAALCENHLHAVYAGANQVMVPAMDFVQSPARFWKALSDYRISYTF 290
>UniRef50_Q83Z53 Cluster: Putisolvin synthetase; n=3; Bacteria|Rep:
Putisolvin synthetase - Pseudomonas putida
Length = 3066
Score = 48.8 bits (111), Expect = 8e-04
Identities = 53/197 (26%), Positives = 80/197 (40%), Gaps = 23/197 (11%)
Query: 463 AQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLD 522
A+ DHV T A LT A L+++A + L+ G V D VA++ L+
Sbjct: 390 AEQYPDHVAATCAGA------CLTYAALNRQANALAQHLISLG-VRPDDRVAVVARRSLE 442
Query: 523 LICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEA 582
+ L GA V + P HP V ++ S +VL+ Q++ L E
Sbjct: 443 TLVGLLAVLKAGAGYVPVDPAHPDE------RVHYLLSDSGPVVVLTQQALQARLGPVEV 496
Query: 583 SNVL-DSKAWPMTLDTDDMPKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVT 641
+L D WP D P + A LAY+ ++ +TG G+ + H V
Sbjct: 497 PVLLLDQPGWPAC---DSNP------LVPGLDASNLAYVIYTSGSTGQPKGVMVEHRTVN 547
Query: 642 SLCRSMKIACELYPSRH 658
+L A +L P RH
Sbjct: 548 NLVDWHCRAFDLCPGRH 564
Score = 40.3 bits (90), Expect = 0.27
Identities = 49/213 (23%), Positives = 91/213 (42%), Gaps = 22/213 (10%)
Query: 441 GYTDDSDAARKYQFISQILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNL 500
G+ D + A Q + ++ + T D V +L +G++S EL+++A R+ +
Sbjct: 2460 GFNDTAVAYNLEQTLHGLIEAQVVRTPDAV--AVLAEEGSLSY----RELNEQANRLAHX 2513
Query: 501 LLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVD 560
L+ G V D VA+ GL ++ L G V + P +P VR ++
Sbjct: 2514 LIALG-VKPDDRVAICVERGLSMVVGLLAILKAGGAYVPVDPDYPTE------RVRHMLS 2566
Query: 561 VSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKKLPIMYRAPTAEMLAYL 620
S VL + + + + + + LD W ++ + +P + T LAY+
Sbjct: 2567 DSAPVAVLVHSATRHVPEAAQLID-LDRPTWNAQPSSNPV----VPTL----TPRHLAYV 2617
Query: 621 DFSVSTTGMLAGIKMSHAAVTSLCRSMKIACEL 653
++ +TG+ G+ HA V + M+ A L
Sbjct: 2618 IYTSGSTGLPKGVMNEHAGVVNRLLWMQDAYNL 2650
Score = 37.5 bits (83), Expect = 1.9
Identities = 48/178 (26%), Positives = 75/178 (42%), Gaps = 19/178 (10%)
Query: 488 AELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQN 547
A L+++A R+ L+ G V G VA++ P L L+ A L GAV V P +
Sbjct: 1451 ATLNERANRLAYYLMGTG-VAPGACVAVLLPRSLQLLVAQLAVLKCGAVYV------PLD 1503
Query: 548 LHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKKLPI 607
+H +V+ +A VL+ + L + + LD L DD P +
Sbjct: 1504 IHAPADRQAFVVEDCQAAAVLTLAATPVDLVVRRVN--LDQ------LSLDDQPGHNPGL 1555
Query: 608 MYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIALCLDP 665
A A AY+ ++ TTG G+ ++H + L + A EL IA +P
Sbjct: 1556 ---AQDAGSTAYVMYTSGTTGKPKGVCVTHRGIARLVLNDSFA-ELTAGDRIAFASNP 1609
>UniRef50_Q5ZPA7 Cluster: TubE protein; n=1; Angiococcus
disciformis|Rep: TubE protein - Angiococcus disciformis
Length = 1181
Score = 48.8 bits (111), Expect = 8e-04
Identities = 91/437 (20%), Positives = 172/437 (39%), Gaps = 32/437 (7%)
Query: 473 TLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLY 532
+ + A+G+ + T EL ++A R+ L + G + GD + L+ + + A + C+
Sbjct: 525 SFVQAQGSCT-AWTLPELVERARRLQAGLRQWG-LRPGDSLVLVLGREEETVEALWACVL 582
Query: 533 VGAVPVTI-RPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIK-LLRSKEASNVLDSKA 590
G P+ + PP L +R + VL+ Q ++ L R + S D
Sbjct: 583 AGVAPLVLPAPPARAEASPALSRLRHARQLLGGPRVLTRQEMLPDLARQLQVSPTADILG 642
Query: 591 WPMTLDTDDMPKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIA 650
L + LP + +A L+ + TTG ++H + + +
Sbjct: 643 AVEELRATG-GEAPLP----PGRMDDVALLNLTSGTTGKAKCAMLTHRNLLVRLEATNVV 697
Query: 651 CELYPSRHIALCLDPYCGLGFALWCLSSIYSGHHSILIPPSEVEVNPALWLSAVSQYKVR 710
E P + L + + + L + +G H+ P EV P WL + +Y +
Sbjct: 698 YESQPLERGLVWLQLHNIGALSEYHLRPLCAGMHTFHAPTEEVLAEPLRWLEWLERYGIA 757
Query: 711 DTFC-SYGVMELCTKGLGSSVNQLKSKGINLACVRTCVVVAEERPRINLTNSFSKLFSAL 769
T+ S+ L + + +++ + +L VR ++ A E+ + + +
Sbjct: 758 QTWAPSFAYSHLLER-----LRKVEDRRWSLGGVRV-LLSAGEQISAPMVEELMRRLAPS 811
Query: 770 GLSPRAVSTSFGCRVNIAICLQGASSPEPSTVYVDLRALRNDRVSLVERGSPHSLCLMES 829
G+ A ++G + P ++ RA + + SP +L LM+
Sbjct: 812 GVREDAFVAAWGMTETASGVTYARRPGTPPRMHTLERASLSGPLRHAAPASPTALRLMDV 871
Query: 830 GKLLPG--VKVITANPETKGQCGDSHLGEIWVQSPHNASGYFTIYGDESDYADHFSAQLV 887
G + G ++V+ A+ E + +G I V+ + GY YGD SA L+
Sbjct: 872 GAPIAGTALRVVDASGEL---LSEECVGRIQVRGEMISPGY---YGDPK-----ASAALL 920
Query: 888 TGNTGEVYARTGYLGFL 904
T + + TG LGFL
Sbjct: 921 ---TADGWLETGDLGFL 934
>UniRef50_A1KAD3 Cluster: Putative long chain fatty acid coA ligase;
n=1; Azoarcus sp. BH72|Rep: Putative long chain fatty
acid coA ligase - Azoarcus sp. (strain BH72)
Length = 586
Score = 48.8 bits (111), Expect = 8e-04
Identities = 54/192 (28%), Positives = 80/192 (41%), Gaps = 15/192 (7%)
Query: 459 LRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFP 518
LR R T F L NA G + A L ++AE + + G V GD VA++ P
Sbjct: 14 LRQRVSVTPSAPAFLLRNADGDWQPMPWSALL-ERAEHLATHFVRLG-VRPGDRVAIMLP 71
Query: 519 PGLDLICAFYGCLYVGAVPVTI-RPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLL 577
G D C Y L GA V I PQNL ++ S A +V + ++ L
Sbjct: 72 TGPDWECCQYAALLAGAAVVGIDAHDAPQNLR------HILAIASPALVVAPDAERLEQL 125
Query: 578 RSKEASN---VLDSKAWPMTLDTDDMPKKKLP--IMYRAPTAEMLAYLDFSVSTTGMLAG 632
RS + ++ ++A P + + P + P A+ +A L F+ +TG G
Sbjct: 126 RSLHPGDWHAIVQAEA-PSDTGLPCLSQLTTPCEALLPEPAADDIATLVFTSGSTGKPKG 184
Query: 633 IKMSHAAVTSLC 644
I SH + C
Sbjct: 185 IAYSHRQILLAC 196
>UniRef50_Q0LKI7 Cluster: AMP-dependent synthetase and ligase; n=1;
Herpetosiphon aurantiacus ATCC 23779|Rep: AMP-dependent
synthetase and ligase - Herpetosiphon aurantiacus ATCC
23779
Length = 1818
Score = 48.4 bits (110), Expect = 0.001
Identities = 76/369 (20%), Positives = 147/369 (39%), Gaps = 25/369 (6%)
Query: 510 GDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVD---VSKATL 566
G HV L F + AF+ C+ G V + P+ + + P V + + + L
Sbjct: 624 GQHVVLQFAHNEPFVVAFWACMLGGFTAVPLALPNSSDPNN--PAVSKLYNTWQTLEQPL 681
Query: 567 VLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKKLPIMYRAPTAEMLAYLDFSVST 626
++S Q+ LL + N L P T+ + + + ++ + A L F+ +
Sbjct: 682 IVSEQASFSLL--QRIFNGL-GVVKPAIQITEQLRQHQPDQQHQHLAPQDSALLLFTSGS 738
Query: 627 TGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGL-GFALWCLSSIYSGHHS 685
TG+ G+++SH + S ++ + ++L P + G ++ + + G
Sbjct: 739 TGLPKGVELSHHNIISRSKA-SAQHNRFDHNDVSLNWMPLDHVGGIVMFHVHDVCLGCRQ 797
Query: 686 ILIPPSEVEVNPALWLSAVSQYKVRDTFCSYGVMELCTKGLGSSVNQLKSKGINLACVRT 745
I + +P WL + QY+ T+ L + ++ S+ NL+ +R
Sbjct: 798 IQAKTDYILEDPVRWLDLLEQYRATITWSPNFAYAL----INDQHERVNSRRRNLSSLRF 853
Query: 746 CVVVAEERPRINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEPSTVYVDL 805
+ E + N F L A GL A+ ++G ++ G SS + +
Sbjct: 854 ILNGGEGINKQTALN-FLGLLQAHGLPATAMHPAYG----MSETSSGISSSDQLVLGATT 908
Query: 806 RALRNDRVSL---VERGSPHSL--CLMESGKLLPGVKVITANPETKGQCGDSHLGEIWVQ 860
D+ SL ++ S S+ +E G LPGV + N + + +G + +Q
Sbjct: 909 GFHELDQASLTGVIQPASADSIGVAFVEVGAPLPGVSLRIVNTNNQ-LLSEDLIGRLQIQ 967
Query: 861 SPHNASGYF 869
P +GY+
Sbjct: 968 GPTITAGYY 976
>UniRef50_Q5D6D6 Cluster: Nonribosomal peptide synthetase 3; n=3;
root|Rep: Nonribosomal peptide synthetase 3 -
Cochliobolus heterostrophus (Drechslera maydis)
Length = 5158
Score = 48.4 bits (110), Expect = 0.001
Identities = 42/161 (26%), Positives = 73/161 (45%), Gaps = 15/161 (9%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPH 544
+T EL + + R+ + L+ G V + V L F + ++ A L G + P H
Sbjct: 2631 MTYEELDETSSRLAHHLISLG-VESESIVPLCFDKSIWVVVAMLAVLKTGGAFAPLDPNH 2689
Query: 545 PQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLD-TDDMPKK 603
P + H R I D +KA ++LS+ L E+S ++ P++ D D +P K
Sbjct: 2690 PTSRH------REIFDQTKAKMILSSTQYANLW--PESSQIVV----PISRDFIDQLPAK 2737
Query: 604 KLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLC 644
AY+ F+ +TG+ G+++ H AV++ C
Sbjct: 2738 PYDAQIAVQPGNT-AYIIFTSGSTGVPKGVQLEHKAVSTSC 2777
>UniRef50_O30409 Cluster: Tyrocidine synthetase 3 (Tyrocidine
synthetase III) [Includes: ATP- dependent asparagine
adenylase (AsnA) (Asparagine activase); ATP- dependent
glutamine adenylase (GlnA) (Glutamine activase); ATP-
dependent tyrosine adenylase (TyrA) (Tyrosine activase);
ATP-dependent valine adenylase (ValA) (Valine activase);
ATP-dependent ornithine adenylase (OrnA) (Ornithine
activase); ATP-dependent leucine adenylase (LeuA)
(Leucine activase)]; n=8; cellular organisms|Rep:
Tyrocidine synthetase 3 (Tyrocidine synthetase III)
[Includes: ATP- dependent asparagine adenylase (AsnA)
(Asparagine activase); ATP- dependent glutamine adenylase
(GlnA) (Glutamine activase); ATP- dependent tyrosine
adenylase (TyrA) (Tyrosine activase); ATP-dependent
valine adenylase (ValA) (Valine activase); ATP-dependent
ornithine adenylase (OrnA) (Ornithine activase);
ATP-dependent leucine adenylase (LeuA) (Leucine
activase)] - Brevibacillus parabrevis
Length = 6486
Score = 48.4 bits (110), Expect = 0.001
Identities = 45/160 (28%), Positives = 76/160 (47%), Gaps = 16/160 (10%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPH 544
LT +EL+++A R+ +L KG V VA++ +++ G L G V + P +
Sbjct: 5682 LTYSELNERANRLARVLRAKG-VGPDRLVAIMAERSPEMVIGILGILKAGGAYVPVDPGY 5740
Query: 545 PQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLR--SKEASNVLDSKAWPMTLDTDDMPK 602
PQ ++ +++ S A L+LS ++ LL S E LD A LD +
Sbjct: 5741 PQE------RIQYLLEDSNAALLLSQAHLLPLLAQVSSELPECLDLNA---ELDAG-LSG 5790
Query: 603 KKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTS 642
LP + + PT LAY+ ++ TTG G+ + H + +
Sbjct: 5791 SNLPAVNQ-PTD--LAYVIYTSGTTGKPKGVMIPHQGIVN 5827
Score = 37.9 bits (84), Expect = 1.5
Identities = 36/161 (22%), Positives = 67/161 (41%), Gaps = 16/161 (9%)
Query: 483 KVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRP 542
++LT EL++KA ++ ++L + G V V L+ L++I G L G + + P
Sbjct: 3599 QMLTYRELNEKANQLAHVLRQNG-VGKESIVGLLADRSLEMITGIMGILKAGGAYLGLDP 3657
Query: 543 PHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPK 602
HP + +L + V +L K ++ P+ L+ + +
Sbjct: 3658 EHPSE---------------RLAYMLEDGGVKVVLVQKHLLPLVGEGLMPIVLEEESLRP 3702
Query: 603 KKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSL 643
+ A LAY+ ++ +TG G+ + H VT L
Sbjct: 3703 EDCGNPAIVNGASDLAYVMYTSGSTGKPKGVMVEHRNVTRL 3743
Score = 36.3 bits (80), Expect = 4.5
Identities = 45/227 (19%), Positives = 101/227 (44%), Gaps = 21/227 (9%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPH 544
LT EL+ KA ++ +L KG V V ++ L ++ L G V I P +
Sbjct: 4636 LTYQELNAKANQLARVLRRKG-VKPESTVGILVDRSLYMVIGMLAVLKAGGTFVPIDPDY 4694
Query: 545 PQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKK 604
P L +++ S+A L+L+ Q + + + + ++ LDT+ + +++
Sbjct: 4695 P------LERQAFMLEDSEAKLLLTLQKM-----NSQVAFPYET----FYLDTETVDQEE 4739
Query: 605 LPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACEL--YPSRHIALC 662
+ E +AY+ ++ TTG G+ + H + ++ + K L +P R + +
Sbjct: 4740 TGNLEHVAQPENVAYIIYTSGTTGKPKGVVIEHRSYANVAFAWKDEYHLDSFPVRLLQMA 4799
Query: 663 LDPYCGLGFALWCLSSIYSGHHSILIPPSEVEVNPALWLSAVSQYKV 709
+ + + + + G ++I P+ V+++PA + ++++
Sbjct: 4800 SFAF-DVSTGDFARALLTGG--QLVICPNGVKMDPASLYETIRRHEI 4843
>UniRef50_Q7N1E3 Cluster: Similar to proteins involved in
antibiotics biosynthesis; n=2; cellular organisms|Rep:
Similar to proteins involved in antibiotics biosynthesis
- Photorhabdus luminescens subsp. laumondii
Length = 1133
Score = 48.0 bits (109), Expect = 0.001
Identities = 38/160 (23%), Positives = 76/160 (47%), Gaps = 15/160 (9%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPH 544
L+ AEL +A +I LLL KG N VA++ PG+D + + L G + + P +
Sbjct: 564 LSFAELDARANQIAQLLLTKGADNN-PLVAILMEPGIDFVVSMLAILKAGCAYLPLDPTY 622
Query: 545 PQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKK 604
+ ++ D +++ N+S+ K+ N+ + LD ++ +
Sbjct: 623 -----SVARLSFILADSHVGLVIVDNKSIDKV-------NLPADSVCTILLDETEIAAQP 670
Query: 605 L--PIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTS 642
P++ + TA+ LAY+ ++ +TG G+ + H A+++
Sbjct: 671 RTEPMLTSSVTADSLAYVIYTSGSTGNPKGVMIQHGALSA 710
>UniRef50_Q6D739 Cluster: Non-ribosomal peptide synthetase; n=3;
cellular organisms|Rep: Non-ribosomal peptide synthetase
- Erwinia carotovora subsp. atroseptica (Pectobacterium
atrosepticum)
Length = 7048
Score = 48.0 bits (109), Expect = 0.001
Identities = 57/272 (20%), Positives = 115/272 (42%), Gaps = 25/272 (9%)
Query: 483 KVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRP 542
++L+ AE++ +A ++ + LL V D +A+ +++ G L GA V + P
Sbjct: 4845 RLLSYAEVNHRANQLAHHLLSLD-VKPDDRIAICVERSPEMVIGLLGILKAGAAYVPLDP 4903
Query: 543 PHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPK 602
+P T + ++ S +L++ S++ L S + +LD+ A +
Sbjct: 4904 SYPTERLTYM------LEDSAPVALLTHSSLVASLSSTAPTILLDNTALFEACSDSNPAA 4957
Query: 603 KKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIALC 662
+ + + T LAY+ ++ +TG G+ + H + + + ++ YP L
Sbjct: 4958 QAIGL-----TPHHLAYIIYTSGSTGKPKGVMVEHRNIVASTYARQLT---YPMFERVLL 5009
Query: 663 LDPYCGLGFALWCLSSIYSGHHSILIPPSEVEVNPALWLSAVSQYKVRDTFCSYGVMELC 722
L AL + + S+ +P E+ V+P L + ++ + C LC
Sbjct: 5010 LSS-IAFDSALASVFGTLTRGGSLYLPQQEITVDPTAILHMLHEHHI----CCL----LC 5060
Query: 723 TKGLGSSVNQLKSKGINLACVRTCVVVAEERP 754
L S+ Q+ S+ LA ++ +V E P
Sbjct: 5061 VPSLALSLLQM-SQNEELASLKALIVAGERCP 5091
Score = 42.7 bits (96), Expect = 0.051
Identities = 40/175 (22%), Positives = 75/175 (42%), Gaps = 10/175 (5%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPH 544
L+ EL+++A R+ + LL G V + VA+ L++I L G V + P +
Sbjct: 3773 LSYDELNRRANRLAHHLLSLG-VQPDNRVAICVERSLEMIVGMLAVLKAGGAYVPLDPSY 3831
Query: 545 PQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKK 604
P + T M+ D + L L+ ++ LL S LD+ P + +
Sbjct: 3832 PADRLTY-----MLEDAAPVAL-LTQTDLVALLHSDLPVIELDNL--PAAIADEGQDSNP 3883
Query: 605 LPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHI 659
+P + T LAY+ ++ +TG G+ + H ++ +L + + H+
Sbjct: 3884 VPQAFGL-TPRHLAYVIYTSGSTGKPKGVMVEHRSMCNLLNGQIESLHIAADSHV 3937
Score = 41.5 bits (93), Expect = 0.12
Identities = 36/158 (22%), Positives = 73/158 (46%), Gaps = 12/158 (7%)
Query: 490 LHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLH 549
L+++A ++ + LL G V D +A+ +++I G L GA V + P +P
Sbjct: 1623 LNRRANQLAHHLLSLG-VQPDDRIAICVERSVEMIVGLLGILKAGAAYVPLDPAYPAE-- 1679
Query: 550 TTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLD-TDDMPKKKLPIM 608
+ ++D +K +L+ ++I+ L S VLD + + + D P +
Sbjct: 1680 ----RLAYMLDDAKPVALLTQTALIETLNSTLPLVVLDDPQFTVFKHASQDNPDAHALGL 1735
Query: 609 YRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRS 646
T+ LAY+ ++ +TG G+ + H ++ +L +
Sbjct: 1736 ----TSHHLAYVIYTSGSTGQPKGVMIEHRSLCNLANA 1769
>UniRef50_Q2SHZ4 Cluster: Non-ribosomal peptide synthetase modules
and related protein; n=1; Hahella chejuensis KCTC
2396|Rep: Non-ribosomal peptide synthetase modules and
related protein - Hahella chejuensis (strain KCTC 2396)
Length = 2624
Score = 48.0 bits (109), Expect = 0.001
Identities = 38/161 (23%), Positives = 77/161 (47%), Gaps = 14/161 (8%)
Query: 483 KVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRP 542
+ L+ EL+++A R+ +LL+ +G + D + + LD+ A GA + P
Sbjct: 500 QTLSYGELNRRANRLAHLLIARG-ITLEDRIGICLDRSLDMAVALLAVFKAGASYAPLDP 558
Query: 543 PHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPK 602
+P + +++ S A L L+ Q+ L + + +LD +T D +D
Sbjct: 559 AYPTE------RIAYMLEDSGARLTLTQQAASGRLPAGVVTLMLDDLE-TLTADCEDSNP 611
Query: 603 KKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSL 643
++ P+ A+ LAY+ ++ +TG+ G+ + H +V +L
Sbjct: 612 QR-PV-----AADNLAYVIYTSGSTGLPKGVAIEHRSVGAL 646
>UniRef50_Q2VQ15 Cluster: Nonribosomal peptide synthetase C; n=3;
Brevibacillus texasporus|Rep: Nonribosomal peptide
synthetase C - Brevibacillus texasporus
Length = 4617
Score = 48.0 bits (109), Expect = 0.001
Identities = 40/160 (25%), Positives = 71/160 (44%), Gaps = 16/160 (10%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPH 544
+T EL+++A R+ L++KG + VA++ ++ + G L G V I P +
Sbjct: 3597 ITYRELNERANRLARCLIDKG-IQRNQFVAIMADRSIETVIGMMGILKAGGAYVPIDPDY 3655
Query: 545 PQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKK 604
P L I++ S A+L+L Q +++ W DT+
Sbjct: 3656 P------LDRKLYILEDSHASLLLFQQKHEVPSEFTGDRILIEQMQWYQAADTN------ 3703
Query: 605 LPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLC 644
+ TA+ LAY+ ++ +TG G+ + H AV +LC
Sbjct: 3704 ---VGIVNTAQDLAYMIYTSGSTGQPKGVMIDHQAVCNLC 3740
>UniRef50_Q1YTY5 Cluster: Long-chain-fatty-acid--CoA ligase; n=2;
Gammaproteobacteria|Rep: Long-chain-fatty-acid--CoA
ligase - gamma proteobacterium HTCC2207
Length = 551
Score = 48.0 bits (109), Expect = 0.001
Identities = 53/227 (23%), Positives = 97/227 (42%), Gaps = 20/227 (8%)
Query: 481 VSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTI 540
+ + L +E+ + + + G LLE + GD VA+ P A +G L G V V
Sbjct: 59 LGQTLCFSEIEQLSRQFGCYLLEHCGLGAGDRVAVQLPNISQFPIAIWGILRAGLVVVNT 118
Query: 541 RPPHP--QNLH----TTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWP-- 592
P + + LH + + ++ D+ T + Q+ ++ + + A ++L + P
Sbjct: 119 NPMYTAREQLHQFNDSGAKALVVLSDLLPVTEQVIPQTGVETVIATSAIDLLQPQPLPAS 178
Query: 593 ----MTLDTDDM---PKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCR 645
+ TD + K+LP R+ + +A L ++ TTG G ++H + R
Sbjct: 179 SLSNLVSFTDALALGADKQLP--ERSSSMSDVAVLQYTGGTTGPSKGAILTHGNIFGGVR 236
Query: 646 SMKIACELYPSRHIALCLDP---YCGLGFALWCLSSIYSGHHSILIP 689
K++ + L + P Y GF + +S G HS+LIP
Sbjct: 237 MSKVSVDFSDEEVPDLLIAPMPLYHVFGFTMNAVSGFLGGSHSVLIP 283
>UniRef50_Q0RL74 Cluster: Putative long-chain-fatty-acid CoA ligase;
n=1; Frankia alni ACN14a|Rep: Putative
long-chain-fatty-acid CoA ligase - Frankia alni (strain
ACN14a)
Length = 566
Score = 48.0 bits (109), Expect = 0.001
Identities = 59/256 (23%), Positives = 108/256 (42%), Gaps = 19/256 (7%)
Query: 622 FSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIALCLDPYCGLGFALWCLSSIYS 681
++ TTG+ G+ ++ + SL R +L P + L P + + + LS ++
Sbjct: 178 YTSGTTGLPKGVMLTEHNLLSLLRMAGETLDLGPDS-VNLVAMPLFHISGSGYSLSGFHA 236
Query: 682 GHHSILIPPSEVEVNPALWLSAVSQYKVRDTFCSYGVME--LCTKGLGS-SVNQLKSKGI 738
G H++L+ E +P L +V ++ V + F V+ L G+ ++ L++
Sbjct: 237 GCHTVLLR----EAHPDTILRSVVEHGVTNLFAVPAVLRTMLGVAGIAELDLSSLRTIAY 292
Query: 739 NLACVRTCVVVAEERPRINLTNSFSKLFSALGLSPRAVSTSFGCRVNIAICLQGASSPEP 798
+ + V+V R F +++ GLS A + + + L+ A +
Sbjct: 293 GASPISLAVLV---RAIETFRCDFVQVY---GLSETAGTVTMLTPEDHRRALETAGTGAG 346
Query: 799 STVYVD--LRALRNDRVSLVERGSPHSLC---LMESGKLLPGVKVITANPETKGQCGDSH 853
T V L AL D+ +R + L +G+ +PG +V P T
Sbjct: 347 GTAEVAGALGALGADKAVGADREVATAGAAGRLRSAGRAVPGARVRIVPPHTGADAEPGE 406
Query: 854 LGEIWVQSPHNASGYF 869
+GEIW+ SP N GY+
Sbjct: 407 VGEIWIHSPQNTPGYW 422
>UniRef50_A0UVH5 Cluster: Amino acid adenylation domain; n=2;
Bacteria|Rep: Amino acid adenylation domain - Clostridium
cellulolyticum H10
Length = 2193
Score = 48.0 bits (109), Expect = 0.001
Identities = 37/177 (20%), Positives = 79/177 (44%), Gaps = 17/177 (9%)
Query: 486 TCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPHP 545
T +L + RI N L+++G ++TG+ V + + + G L G V + P +P
Sbjct: 1607 TYGQLDSLSSRIANYLVKQG-LHTGEPVGVSIERSPEAVACILGILKAGGAYVPLDPSYP 1665
Query: 546 QNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKKL 605
+ + +++ S LVL+ + ++K + + +D ++ ++DD P+ K
Sbjct: 1666 KE------RIAFMLEDSGLKLVLTKKDILKGVETNAVMLCIDECMQQISEESDDSPENK- 1718
Query: 606 PIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIALC 662
+ +AY+ ++ +TG G++ H + + C M YP + +C
Sbjct: 1719 ------ADSGSVAYIIYTSGSTGKPKGVQGLHKGIINRCNWM---WRTYPYKEEEIC 1766
Score = 44.8 bits (101), Expect = 0.013
Identities = 36/177 (20%), Positives = 78/177 (44%), Gaps = 17/177 (9%)
Query: 486 TCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPHP 545
T +L + RI N L+++G ++ G+ V + + + G L G V + P +P
Sbjct: 547 TYGQLDSLSSRIANYLVKQG-LHIGEPVGVSIERSPEAVACILGILKAGGAYVPMDPSYP 605
Query: 546 QNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKKL 605
+ + +++ S LVL+ + ++K + + +D ++ ++DD P+ K
Sbjct: 606 K------ARIAFMLEDSGLKLVLTKKDILKGVETNAVMLCIDECMQQISEESDDSPENK- 658
Query: 606 PIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHIALC 662
+ +AY+ ++ +TG G++ H + + C M YP + +C
Sbjct: 659 ------ADSGSVAYIIYTSGSTGRPKGVQGLHKGIINRCNWM---WRTYPYKEEEIC 706
>UniRef50_A0NTU6 Cluster: Putative non-ribosomal peptide synthetase;
n=1; Stappia aggregata IAM 12614|Rep: Putative
non-ribosomal peptide synthetase - Stappia aggregata IAM
12614
Length = 4579
Score = 48.0 bits (109), Expect = 0.001
Identities = 43/178 (24%), Positives = 78/178 (43%), Gaps = 10/178 (5%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPH 544
LT AEL +A R+ +LL+ +G + D VA+ P D+I A L GA + + P +
Sbjct: 3745 LTYAELEDRANRLAHLLIRRG-IGAEDRVAIALPRSPDMIVALLAVLKSGAAYLPLDPDY 3803
Query: 545 PQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRS---KEASNVLDSKAWPMTLDTDDMP 601
P + M+++ + LV+S + ++L A +LD++A L
Sbjct: 3804 PS------ARIAMMLEDASPRLVISETATAQVLTDGVPTSALLLLDAQATGTELAAMSAL 3857
Query: 602 KKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACELYPSRHI 659
+A AY+ ++ +TG G+ ++ A+ +L + I L P +
Sbjct: 3858 SPTNADRRQAIHPAHPAYVIYTSGSTGKPKGVVVTREALKNLLCCLSIEIRLRPQDRV 3915
Score = 45.6 bits (103), Expect = 0.007
Identities = 42/162 (25%), Positives = 75/162 (46%), Gaps = 10/162 (6%)
Query: 484 VLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPP 543
VLT EL +KA R+ L+ +G + +G+ VAL G DL+ G + GA + + P
Sbjct: 67 VLTFEELDRKANRVAWYLIRRG-IGSGNIVALGCAAGPDLVVCLLGVIKAGACYMPLDPA 125
Query: 544 HPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASN---VLDSKAWPMTLDTDDM 600
+P+ T M+ D ++ L+L+ QSV +++ + + + L S A +
Sbjct: 126 YPRQRLTD-----MLQD-AQPDLILAEQSVAEIVAAADQTQQAVFLGSGALSREIAAQPE 179
Query: 601 PKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTS 642
+ R + AYL ++ +TG G+ AA+ +
Sbjct: 180 TAPLGKDLLRGQSGNDPAYLVYTSGSTGRPKGVLGRQAALAN 221
>UniRef50_UPI00015B53A6 Cluster: PREDICTED: similar to AMP dependent
coa ligase; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to AMP dependent coa ligase - Nasonia
vitripennis
Length = 739
Score = 47.6 bits (108), Expect = 0.002
Identities = 43/178 (24%), Positives = 76/178 (42%), Gaps = 10/178 (5%)
Query: 479 GAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPV 538
G ++ T A+ A + LL+ G V G+ VALI P + AF GCL G V
Sbjct: 254 GVTNRKYTYAQARDYANYVARSLLDIG-VKPGEVVALILPNLPETAIAFLGCLEAGIVIT 312
Query: 539 TIRPPHP------QNLHTTLPTVRMIVDVSKATLVLSNQSVI--KLLRSKEASNVLDSKA 590
T+ P + Q + + V ++S + N+S+ +++ + + +
Sbjct: 313 TVNPIYTADEIARQLISSGTKAVITAAEISSTVITAVNKSIPGGRVIVVNDHTKPIPDGV 372
Query: 591 WPMTLDTDDMPKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMK 648
P D K P+ R + + +A L +S TTG+ G+ ++H + S +K
Sbjct: 373 IPFE-DLITKGKTLAPLPDRQWSLDDVAILPYSSGTTGLPKGVMLTHRNIVSNVEMVK 429
>UniRef50_Q5YPH7 Cluster: Putative non-ribosomal peptide synthetase;
n=2; cellular organisms|Rep: Putative non-ribosomal
peptide synthetase - Nocardia farcinica
Length = 8426
Score = 47.6 bits (108), Expect = 0.002
Identities = 43/161 (26%), Positives = 72/161 (44%), Gaps = 11/161 (6%)
Query: 483 KVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRP 542
+ LT AEL +A R+ LL+ G V V L P G++L+ A Y L G V + P
Sbjct: 1220 ETLTYAELSARANRLARLLIAAG-VGPESLVVLAMPRGVELVVAMYAVLRAGGAYVPVDP 1278
Query: 543 PHP-QNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMP 601
HP + + L T V ++ A ++ ++ + + LD + T D
Sbjct: 1279 AHPAERVGHILATAAPRVVLTTAAAGVAPAALPAGVPVHQVDE-LDLSGYAPTRIAD--- 1334
Query: 602 KKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTS 642
++ P+ P AY+ F+ +TG G+ +SH A+ +
Sbjct: 1335 HERAPLHPDNP-----AYVIFTSGSTGKPKGVSVSHRAIVN 1370
Score = 41.1 bits (92), Expect = 0.16
Identities = 64/268 (23%), Positives = 109/268 (40%), Gaps = 26/268 (9%)
Query: 386 LEGTLHPSNVLMCPHTCVTNLPKPREIHSDVGPASVIVGNLVQGNRLASAQGRDM---GY 442
L G+L + L P T T + + +G A+ V L A+ R + +
Sbjct: 2204 LSGSLRYATDLFDPATAATLAARFTRV---LGAAATAPDTAVGAVELLDAEERALVLHRW 2260
Query: 443 TDDSDAARKYQFISQILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLL 502
D + A + ++ + +A T D T A G LT AE + R+ L+
Sbjct: 2261 NDTAHALAQDGTLADLFARQAARTPDRPALT---ADGVT---LTYAEFAARVNRLARWLI 2314
Query: 503 EKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVS 562
+G V VAL +DL+ Y G + + P P R I+D +
Sbjct: 2315 GQG-VGPDALVALGMRRSIDLVVGMYAVTVAGGGYLPLDPDLPAE------RTRHILDTA 2367
Query: 563 KATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKKLPIMYRAPTAEMLAYLDF 622
VL+ + + L ++ + LD + +P T D +++ P+ A AY+ F
Sbjct: 2368 IPVAVLTAGTDLDLPVAQIRIDRLDLERYPTTPVRD--AERRAPLR-----AAHTAYVLF 2420
Query: 623 SVSTTGMLAGIKMSHAAVTSLCRSMKIA 650
+ +TG G+ ++HAAV + R M+ A
Sbjct: 2421 TSGSTGRPKGVAVAHAAVVNRLRWMQEA 2448
Score = 41.1 bits (92), Expect = 0.16
Identities = 45/182 (24%), Positives = 77/182 (42%), Gaps = 15/182 (8%)
Query: 462 RAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGL 521
+A +T D + G+ + VL+ EL ++ ++ L+ G V VAL
Sbjct: 5445 QAAATPDDPAVIHVPDDGSAAAVLSYGELDRRGNQLARHLIGLG-VGPESLVALAIRRST 5503
Query: 522 DLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKE 581
DL+ A Y L G V I P HP L ++ + A L+++ +
Sbjct: 5504 DLVVAMYAVLKAGGAYVPIDPDHP-----PLRIAHVLDTAAPAALLVTTDVTLDYDGPVV 5558
Query: 582 ASNVLDSKAWPMTLDTDDMPKKKLPIMYRAPT-AEMLAYLDFSVSTTGMLAGIKMSHAAV 640
A +D+ A D P+++ R P + AY+ F+ +TG G+ +SHAA+
Sbjct: 5559 A---VDTVALDGYADDPVAPEER-----RGPLHPDNPAYVLFTSGSTGKPKGVSVSHAAI 5610
Query: 641 TS 642
+
Sbjct: 5611 VN 5612
Score = 39.9 bits (89), Expect = 0.36
Identities = 44/160 (27%), Positives = 72/160 (45%), Gaps = 17/160 (10%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPH 544
L+ AE +A R+ L+ +G V G VAL +DL+ Y G V I P H
Sbjct: 4419 LSYAEFAARARRLARWLVSQG-VAPGSAVALGMRRSVDLVVGMYAVTLAGGAYVPIDPEH 4477
Query: 545 P-QNLHTTLPTVRMI-VDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPK 602
P + + L T R + V + A L + +++ R E S D P+ D +
Sbjct: 4478 PAERVEYVLRTARPVCVLTAGADLSVGTAPQVRVDR-LELSRFADG---PIR-DAE---- 4528
Query: 603 KKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTS 642
++ P+ P AY+ F+ +TG G+ ++HAA+ +
Sbjct: 4529 RRAPLRPGHP-----AYVLFTSGSTGRPKGVAVAHAAIVN 4563
Score = 39.9 bits (89), Expect = 0.36
Identities = 40/157 (25%), Positives = 65/157 (41%), Gaps = 9/157 (5%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPH 544
LT E R+ +L+ +G V VAL P +L+ A Y L GA V + P H
Sbjct: 7594 LTYGEFAAAVNRLARVLIGRG-VGPESLVALAIPRSTELLVAMYAVLTAGAGYVPLDPAH 7652
Query: 545 PQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKK 604
P T ++ +++S ++ + R VLD + D P +
Sbjct: 7653 PLE-----RTTAVLAAADPELVLVSTRAPMLPERVSGLEIVLDIAG--IGTDVPAHPVRP 7705
Query: 605 LPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVT 641
++ A+ AY+ F+ +TG G+ + AAVT
Sbjct: 7706 YELVRPVHPAD-TAYVIFTSGSTGAPKGVVVPQAAVT 7741
>UniRef50_A5N8C2 Cluster: Predicted nonribosomal peptide synthetase;
n=1; Clostridium kluyveri DSM 555|Rep: Predicted
nonribosomal peptide synthetase - Clostridium kluyveri
DSM 555
Length = 1791
Score = 47.6 bits (108), Expect = 0.002
Identities = 53/229 (23%), Positives = 96/229 (41%), Gaps = 24/229 (10%)
Query: 483 KVLTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRP 542
K L+ E++KKA I L EK +N GD+V + P D + G L +GA V
Sbjct: 528 KSLSYNEVYKKAVEIAITLREKS-INKGDYVVVKLPHNADQVSCILGILMIGAAYV---- 582
Query: 543 PHPQNLHTTLPTVRMIVDVSKATLVLSNQSV-IKLLRSKEASNVLDSKAWPMTLDTDDMP 601
P ++ T+ IV + +V++++ K N+ K T +D+
Sbjct: 583 --PVDIDTSKKRFESIVKQCNSKVVITDKEFNEKFAEIINVKNIEVEKDMIETFKVEDID 640
Query: 602 KKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSH-AAVTSLCRSMKIACELYPSRHIA 660
+AY+ F+ TTG+ G+ +SH AA+ ++C I ++ +
Sbjct: 641 PYS------------IAYVIFTSGTTGVPKGVLISHSAALNTIC---DINERFGVTKKDS 685
Query: 661 LCLDPYCGLGFALWCLSSIYSGHHSILIPPSEVEVNPALWLSAVSQYKV 709
+ +++ + + S +I+ P E +NP W V +Y +
Sbjct: 686 ILAISKLNFDLSVYDIFGMLSVGGTIVYPNEEDYLNPIHWDELVKEYSI 734
>UniRef50_A3TIE6 Cluster: FadD13; n=2; Actinomycetales|Rep: FadD13 -
Janibacter sp. HTCC2649
Length = 481
Score = 47.6 bits (108), Expect = 0.002
Identities = 31/79 (39%), Positives = 41/79 (51%), Gaps = 4/79 (5%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRP-- 542
LT AEL ++A R+ L+ G V GD V + P G I AF G L GAVPV I P
Sbjct: 36 LTYAELWQRASRVAGGLVGGG-VGPGDRVGVALPNGAPWILAFLGTLLAGAVPVPINPRL 94
Query: 543 PHPQNLH-TTLPTVRMIVD 560
P+ H T R++++
Sbjct: 95 TGPERAHIVTDSGARLVIE 113
>UniRef50_Q2SGN2 Cluster: Non-ribosomal peptide synthetase modules
and related protein; n=1; Hahella chejuensis KCTC
2396|Rep: Non-ribosomal peptide synthetase modules and
related protein - Hahella chejuensis (strain KCTC 2396)
Length = 2159
Score = 47.2 bits (107), Expect = 0.002
Identities = 48/165 (29%), Positives = 79/165 (47%), Gaps = 18/165 (10%)
Query: 482 SKVLTCAELHKKAERIGNLLLEKGRVNTGDHVALI---FPPGLDLICAFYGCLYVGAVPV 538
++ LT L+++A R+ + L R GD +A++ G+D I A G L GA
Sbjct: 50 AETLTYDVLNRRANRLAHEL----RRRYGDELAVVGVCLDRGIDAIVAVLGALKAGAAYA 105
Query: 539 TIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTD 598
+ +P L I+ S ++V+S+ +I+ L A LD A+ + D +
Sbjct: 106 PVDMSYP------LERQAYILRDSNVSVVISSAEIIRALPDTFA--FLDMDAYDFSGDAN 157
Query: 599 DMPKKKLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSL 643
D + + P RA T E LAYL ++ +TG G+ M H A+ +L
Sbjct: 158 D-DESQNPS--RACTPEDLAYLIYTSGSTGAPKGVCMPHKALVNL 199
>UniRef50_Q3EYR3 Cluster: Peptide synthetase; n=3; Bacillus cereus
group|Rep: Peptide synthetase - Bacillus thuringiensis
serovar israelensis ATCC 35646
Length = 1209
Score = 47.2 bits (107), Expect = 0.002
Identities = 44/169 (26%), Positives = 83/169 (49%), Gaps = 20/169 (11%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPH 544
LT EL+KK+ +I ++L++ G V GD+V + +D + + L GA V I P +
Sbjct: 259 LTYEELNKKSNQIAHMLIKNG-VQLGDYVGIFMKRSIDTVVSMVAILKAGAAYVPIDPDY 317
Query: 545 PQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNVLDSKAWPMTLDTDDMPKKK 604
P++ ++ I+ S+A ++L ++ I + ++ DS+ T + D+ K
Sbjct: 318 PES------RIQYIIQDSQAKVILMKETPI-TCDGVQTVSMYDSE----TCEDIDV---K 363
Query: 605 LPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAVTSLCRSMKIACEL 653
L I + +AY+ ++ +TG G ++H V +L M+ EL
Sbjct: 364 LSI-----HCDDVAYMIYTSGSTGNPKGTMLAHRGVVNLYIWMQKQYEL 407
>UniRef50_A4C379 Cluster: Non-ribosomal peptide synthetase, terminal
component; n=1; Pseudoalteromonas tunicata D2|Rep:
Non-ribosomal peptide synthetase, terminal component -
Pseudoalteromonas tunicata D2
Length = 3345
Score = 47.2 bits (107), Expect = 0.002
Identities = 37/157 (23%), Positives = 74/157 (47%), Gaps = 7/157 (4%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPH 544
L+ EL+ KA ++ + L + V V L L+++ +G L G V + P
Sbjct: 567 LSYGELNAKANQLAHYLRAEHGVGPDSLVGLCTERSLEMVIGIWGILKAGGAYVPLDPEL 626
Query: 545 PQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNV-LDSKAWPMTLDTDDMPKK 603
P ++ +V ++A +VLS Q++ + + EA V LD +T + ++
Sbjct: 627 PS------ARLQYLVSDTQANVVLSTQALKEHITLGEAQVVYLDGLGSQVTHPFSEYSEE 680
Query: 604 KLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAV 640
+ + T++ LAY+ ++ +TG G+ ++H A+
Sbjct: 681 NINLKEIGLTSQHLAYMIYTSGSTGQPKGVLLAHQAL 717
Score = 47.2 bits (107), Expect = 0.002
Identities = 37/157 (23%), Positives = 74/157 (47%), Gaps = 7/157 (4%)
Query: 485 LTCAELHKKAERIGNLLLEKGRVNTGDHVALIFPPGLDLICAFYGCLYVGAVPVTIRPPH 544
L+ EL+ KA ++ + L + V V L L+++ +G L G V + P
Sbjct: 2751 LSYGELNAKANQLAHYLRAEHGVGPDSLVGLCTERSLEMVIGIWGILKAGGAYVPLDPEL 2810
Query: 545 PQNLHTTLPTVRMIVDVSKATLVLSNQSVIKLLRSKEASNV-LDSKAWPMTLDTDDMPKK 603
P ++ +V ++A +VLS Q++ + + EA V LD +T + ++
Sbjct: 2811 PS------ARLQYLVSDTQANVVLSTQALKEHITLGEAQVVYLDGLGSQVTHPFSEYSEE 2864
Query: 604 KLPIMYRAPTAEMLAYLDFSVSTTGMLAGIKMSHAAV 640
+ + T++ LAY+ ++ +TG G+ ++H A+
Sbjct: 2865 NINLKEIGLTSQHLAYMIYTSGSTGQPKGVLLAHQAL 2901
>UniRef50_A3I9A7 Cluster: Peptide synthetase; n=1; Bacillus sp.
B14905|Rep: Peptide synthetase - Bacillus sp. B14905
Length = 1055
Score = 47.2 bits (107), Expect = 0.002
Identities = 46/193 (23%), Positives = 87/193 (45%), Gaps = 24/193 (12%)
Query: 455 ISQILRWRAQSTSDHVIFTLLNAKGAVSKVLTCAELHKKAERIGNLLLEKGRVNTGDHVA 514
I Q+ AQ +D + + + K +T +L++K+ ++ ++L+ G + GD+VA
Sbjct: 56 IPQVFYQVAQQFADRIALSYEDGK------MTYRQLNQKSNQVAHMLIANG-LQKGDYVA 108
Query: 515 LIFPPGLDLICAFYGCLYVGAVPVTIRPPHPQNLHTTLPTVRMIVDVSKATLVLSNQS-- 572
+I + I + G L G V V I P +P+ L + D ++ N+
Sbjct: 109 IIMDRSKETIISLLGVLKAGGVYVPIDPSYPKERCQYL-----LHDTGAPFIITKNEYND 163
Query: 573 -VIKLLRSK-EASNVLDSKAWPMTLDTDDMPKKKLPIMYRAPTAEMLAYLDFSVSTTGML 630
+ L+ ++ ++ VL L +D+P LP LAY+ ++ +TG
Sbjct: 164 LLNDLIHNEFQSRTVLTINQMESGLSQEDLPCNLLP--------SDLAYIIYTSGSTGKP 215
Query: 631 AGIKMSHAAVTSL 643
G+ + H AV +L
Sbjct: 216 KGVLLKHTAVINL 228
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.322 0.135 0.415
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 1,091,823,873
Number of Sequences: 1657284
Number of extensions: 42456074
Number of successful extensions: 87102
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 183
Number of HSP's successfully gapped in prelim test: 514
Number of HSP's that attempted gapping in prelim test: 84458
Number of HSP's gapped (non-prelim): 2631
length of query: 1071
length of database: 575,637,011
effective HSP length: 109
effective length of query: 962
effective length of database: 394,993,055
effective search space: 379983318910
effective search space used: 379983318910
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.9 bits)
S2: 78 (35.5 bits)
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