Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA002138-TA|BGIBMGA002138-PA|IPR000436|Sushi/SCR/CCP,
IPR006585|Fucolectin tachylectin-4 pentraxin-1, IPR001304|C-type
lectin, IPR003006|Immunoglobulin/major histocompatibility complex,
IPR008979|Galactose-binding like
(1091 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AY210419-1|AAO34702.1| 3501|Homo sapiens CUB and sushi multiple ... 343 3e-93
AB114605-1|BAC82444.1| 3667|Homo sapiens CSMD3 protein isoform 2... 335 6e-91
AB114604-1|BAC82443.1| 3707|Homo sapiens CSMD3 protein isoform 1... 335 6e-91
AB067481-1|BAB67787.2| 2977|Homo sapiens KIAA1894 protein protein. 335 6e-91
AF333704-1|AAK73475.2| 3566|Homo sapiens CUB and sushi multiple ... 317 2e-85
AB209502-1|BAD92739.1| 2966|Homo sapiens CUB and Sushi multiple ... 316 2e-85
AY243503-1|AAQ89957.1| 3574|Homo sapiens selectin-like protein p... 313 2e-84
AL592463-2|CAH73558.1| 3548|Homo sapiens sushi, von Willebrand f... 313 2e-84
AL354982-2|CAH74139.1| 3548|Homo sapiens sushi, von Willebrand f... 313 2e-84
AL158158-3|CAI14068.1| 3548|Homo sapiens sushi, von Willebrand f... 313 2e-84
AJ619977-1|CAF04067.1| 3574|Homo sapiens SEL-OB protein protein. 313 2e-84
AY916667-1|AAX12481.1| 1497|Homo sapiens CCP module-containing p... 312 5e-84
AL158158-6|CAI14071.1| 1497|Homo sapiens sushi, von Willebrand f... 312 5e-84
AY210418-1|AAO34701.1| 3487|Homo sapiens CUB and sushi multiple ... 312 6e-84
BX538049-1|CAD97988.1| 1323|Homo sapiens hypothetical protein pr... 309 3e-83
BX537918-1|CAD97901.1| 1441|Homo sapiens hypothetical protein pr... 308 1e-82
AK075235-1|BAC11489.1| 1497|Homo sapiens protein ( Homo sapiens ... 301 6e-81
AB212622-1|BAD97692.1| 3631|Homo sapiens CSMD2 protein protein. 295 7e-79
AB067471-1|BAB67777.1| 946|Homo sapiens KIAA1884 protein protein. 293 2e-78
AY017307-1|AAG52948.1| 3389|Homo sapiens CUB and sushi multiple ... 288 8e-77
AF308289-1|AAG48257.1| 481|Homo sapiens serologically defined b... 248 8e-65
Z99572-7|CAI23063.1| 829|Homo sapiens selectin P (granule membr... 235 6e-61
Z99572-5|CAI23058.1| 830|Homo sapiens selectin P (granule membr... 235 6e-61
AL022146-7|CAI22757.1| 829|Homo sapiens selectin P (granule mem... 235 6e-61
AL022146-2|CAI22753.1| 830|Homo sapiens selectin P (granule mem... 235 6e-61
BC068533-1|AAH68533.1| 829|Homo sapiens selectin P (granule mem... 235 8e-61
Y00816-1|CAA68755.1| 2039|Homo sapiens protein ( Human mRNA for ... 234 1e-60
X05309-1|CAA28933.1| 1537|Homo sapiens protein ( Human mRNA for ... 234 1e-60
L17418-2|AAB60694.1| 2039|Homo sapiens complement receptor 1 pro... 234 1e-60
L17418-1|AAB60695.1| 2489|Homo sapiens complement receptor 1 pro... 234 1e-60
AL691452-3|CAI16723.1| 2039|Homo sapiens complement component (3... 234 1e-60
AL691452-2|CAI16725.1| 2039|Homo sapiens complement component (3... 234 1e-60
AL691452-1|CAI16724.1| 2039|Homo sapiens complement component (3... 234 1e-60
AL137789-3|CAI16042.1| 2039|Homo sapiens complement component (3... 234 1e-60
AL137789-2|CAI16044.1| 2039|Homo sapiens complement component (3... 234 1e-60
AL137789-1|CAI16043.1| 2039|Homo sapiens complement component (3... 234 1e-60
BC028067-1|AAH28067.2| 789|Homo sapiens SELP protein protein. 234 1e-60
AF542391-1|AAN06828.1| 830|Homo sapiens selectin P (granule mem... 233 3e-60
M60234-1|AAA35910.1| 830|Homo sapiens granule membrane protein-... 231 1e-59
M25322-1|AAA35911.1| 830|Homo sapiens protein ( Human granule m... 231 1e-59
M26016-1|AAB04638.1| 1033|Homo sapiens CR2 protein. 226 4e-58
M26004-1|AAA35786.1| 1033|Homo sapiens CR2 protein. 226 4e-58
AL691452-9|CAI16731.1| 971|Homo sapiens complement component (3... 226 4e-58
AL691452-7|CAI16730.1| 1033|Homo sapiens complement component (3... 226 4e-58
AL391597-7|CAH72949.1| 1033|Homo sapiens complement component (3... 226 4e-58
AL391597-6|CAH72951.1| 971|Homo sapiens complement component (3... 226 4e-58
BC090937-1|AAH90937.1| 1033|Homo sapiens complement component (3... 225 5e-58
Y00649-1|CAA68674.1| 1032|Homo sapiens CR2 receptor protein. 219 4e-56
Z99572-8|CAI23064.1| 753|Homo sapiens selectin P (granule membr... 217 2e-55
Z99572-2|CAI23061.1| 768|Homo sapiens selectin P (granule membr... 217 2e-55
AL022146-8|CAI22758.1| 753|Homo sapiens selectin P (granule mem... 217 2e-55
AL022146-5|CAI22751.1| 768|Homo sapiens selectin P (granule mem... 217 2e-55
J03565-1|AAA35784.1| 1087|Homo sapiens CR2 protein. 213 2e-54
EF064746-1|ABK41929.1| 1092|Homo sapiens complement component (3... 213 2e-54
AL691452-8|CAI16729.1| 1092|Homo sapiens complement component (3... 213 2e-54
AL391597-5|CAH72950.1| 1092|Homo sapiens complement component (3... 213 2e-54
AK223627-1|BAD97347.1| 1092|Homo sapiens complement component (3... 213 2e-54
Z99572-4|CAI23057.1| 768|Homo sapiens selectin P (granule membr... 206 3e-52
AL022146-1|CAI22752.1| 768|Homo sapiens selectin P (granule mem... 206 3e-52
M62486-1|AAA36506.1| 597|Homo sapiens C4b-binding protein alpha... 187 2e-46
M31452-1|AAA36507.1| 597|Homo sapiens C4b-binding protein alpha... 187 2e-46
BC022312-1|AAH22312.1| 597|Homo sapiens complement component 4 ... 187 2e-46
AL445493-8|CAH70782.1| 597|Homo sapiens complement component 4 ... 187 2e-46
Z99572-3|CAI23059.1| 644|Homo sapiens selectin P (granule membr... 185 7e-46
AL022146-3|CAI22754.1| 644|Homo sapiens selectin P (granule mem... 185 7e-46
X14362-1|CAA32541.1| 559|Homo sapiens protein ( Human CR1 mRNA ... 185 9e-46
AL691452-6|CAI16728.1| 559|Homo sapiens complement component (3... 185 9e-46
AL691452-5|CAI16727.1| 559|Homo sapiens complement component (3... 185 9e-46
AL691452-4|CAI16726.1| 559|Homo sapiens complement component (3... 185 9e-46
M61893-1|AAA52375.1| 610|Homo sapiens endothelial leukocyte adh... 177 1e-43
M30640-1|AAA52377.1| 610|Homo sapiens endothelial leukocyte adh... 177 1e-43
BC131551-1|AAI31552.1| 610|Homo sapiens selectin E (endothelial... 177 1e-43
AL021940-6|CAA17434.1| 610|Homo sapiens selectin E (endothelial... 177 1e-43
AF540378-1|AAN01237.1| 610|Homo sapiens selectin E (endothelial... 177 1e-43
M24736-1|AAA52376.1| 610|Homo sapiens endothelial leukocyte adh... 177 2e-43
X02865-1|CAA26617.1| 518|Homo sapiens protein ( Human mRNA frag... 176 3e-43
BC109191-1|AAI09192.1| 526|Homo sapiens CR1L protein protein. 171 9e-42
Y00716-1|CAA68704.1| 1231|Homo sapiens factor H protein. 169 6e-41
M17517-1|AAA52016.1| 657|Homo sapiens HF protein. 169 6e-41
DQ233256-1|ABB02180.1| 1231|Homo sapiens complement factor H pro... 169 6e-41
AL049744-1|CAI19672.1| 1231|Homo sapiens complement factor H pro... 169 6e-41
AL021940-2|CAI19358.1| 547|Homo sapiens selectin E (endothelial... 153 3e-36
AY114160-1|AAM47024.1| 388|Homo sapiens complement C4b binding ... 153 4e-36
Z99572-6|CAI23062.1| 645|Homo sapiens selectin P (granule membr... 152 8e-36
Z99572-1|CAI23060.1| 646|Homo sapiens selectin P (granule membr... 152 8e-36
AL022146-6|CAI22756.1| 645|Homo sapiens selectin P (granule mem... 152 8e-36
AL022146-4|CAI22755.1| 646|Homo sapiens selectin P (granule mem... 152 8e-36
AL021940-5|CAI19359.1| 547|Homo sapiens selectin E (endothelial... 149 7e-35
AK095627-1|BAC04593.1| 505|Homo sapiens protein ( Homo sapiens ... 139 6e-32
AL021940-3|CAI19357.1| 485|Homo sapiens selectin E (endothelial... 133 3e-30
M14057-1|AAA88042.1| 660|Homo sapiens F13A1 protein. 128 1e-28
AY692223-1|AAT85802.1| 661|Homo sapiens coagulation factor XIII... 128 1e-28
AL353809-2|CAH72549.1| 661|Homo sapiens coagulation factor XIII... 128 1e-28
AL021940-4|CAI19360.1| 484|Homo sapiens selectin E (endothelial... 128 1e-28
M64554-1|AAA51821.1| 661|Homo sapiens coagulation factor XIIIb ... 124 2e-27
X07523-1|CAA30403.1| 449|Homo sapiens complement factor H protein. 117 3e-25
X04697-1|CAB41739.1| 397|Homo sapiens protein ( Human mRNA for ... 117 3e-25
BC110643-1|AAI10644.1| 449|Homo sapiens complement factor H pro... 117 3e-25
BC037285-1|AAH37285.1| 449|Homo sapiens complement factor H pro... 117 3e-25
BC111773-1|AAI11774.1| 569|Homo sapiens complement factor H-rel... 113 2e-24
AL353809-1|CAH72548.1| 593|Homo sapiens complement factor H-rel... 113 2e-24
AL139418-4|CAI21982.1| 593|Homo sapiens complement factor H-rel... 113 2e-24
AF295327-1|AAK15619.1| 569|Homo sapiens complement factor H-rel... 113 2e-24
AY358404-1|AAQ88770.1| 910|Homo sapiens PSK-1 protein. 106 5e-22
AJ245822-1|CAB57952.1| 840|Homo sapiens type I transmembrane re... 106 5e-22
EF076058-1|ABK81638.1| 355|Homo sapiens CD46 protein. 101 1e-20
EF076057-1|ABK81637.1| 355|Homo sapiens CD46 protein. 101 1e-20
M29964-1|AAB59520.1| 252|Homo sapiens C4BPB protein. 101 2e-20
L11245-1|AAA35616.1| 252|Homo sapiens C4b-binding protein beta-... 101 2e-20
L11244-1|AAA35615.1| 252|Homo sapiens C4b-binding protein beta-... 101 2e-20
BC005378-1|AAH05378.1| 251|Homo sapiens complement component 4 ... 101 2e-20
AL445493-7|CAH70781.1| 251|Homo sapiens complement component 4 ... 101 2e-20
AL445493-6|CAH70780.1| 252|Homo sapiens complement component 4 ... 101 2e-20
M15799-1|AAA52167.1| 376|Homo sapiens DAF protein. 98 1e-19
X58100-1|CAA41113.1| 345|Homo sapiens Beta-2-glycoprotein I ap... 98 2e-19
X53595-1|CAA37664.1| 345|Homo sapiens beta-2-glycoprotein I pro... 98 2e-19
BC000567-1|AAH00567.1| 809|Homo sapiens SEZ6L2 protein protein. 98 2e-19
AK074998-1|BAC11345.1| 578|Homo sapiens protein ( Homo sapiens ... 98 2e-19
AJ245820-1|CAB57950.1| 853|Homo sapiens type I transmembrane re... 98 2e-19
M31516-1|AAA52169.1| 381|Homo sapiens decay-accelerating factor... 97 2e-19
M30142-1|AAA52168.1| 381|Homo sapiens decay-accelerating factor... 97 2e-19
BT007159-1|AAP35823.1| 381|Homo sapiens decay accelerating fact... 97 2e-19
BC001288-1|AAH01288.1| 381|Homo sapiens CD55 molecule, decay ac... 97 2e-19
AY851161-1|AAW29942.1| 381|Homo sapiens decay accelerating fact... 97 2e-19
AL596218-5|CAI16464.1| 293|Homo sapiens CD55 molecule, decay ac... 97 2e-19
AL596218-4|CAI16463.1| 381|Homo sapiens CD55 molecule, decay ac... 97 2e-19
AL596218-2|CAI16461.1| 444|Homo sapiens CD55 molecule, decay ac... 97 2e-19
AL391597-4|CAH72948.1| 293|Homo sapiens CD55 molecule, decay ac... 97 2e-19
AL391597-2|CAH72946.1| 381|Homo sapiens CD55 molecule, decay ac... 97 2e-19
AL391597-1|CAH72945.1| 444|Homo sapiens CD55 molecule, decay ac... 97 2e-19
AB240570-1|BAE97426.1| 551|Homo sapiens decay-accelerating fact... 97 2e-19
AB240569-1|BAE97425.1| 525|Homo sapiens decay-accelerating fact... 97 2e-19
AB240568-1|BAE97424.1| 384|Homo sapiens decay-accelerating fact... 97 2e-19
AB240567-1|BAE97423.1| 364|Homo sapiens decay-accelerating fact... 97 2e-19
AB240566-1|BAE97422.1| 439|Homo sapiens decay-accelerating fact... 97 2e-19
Y11493-1|CAA72279.1| 345|Homo sapiens beta-2-glycoprotein I pro... 97 3e-19
X57847-1|CAA40977.1| 345|Homo sapiens Apolipoprotein H (beta2-... 97 3e-19
U88576-1|AAB48622.1| 347|Homo sapiens decay-acceleration factor... 97 3e-19
S80305-1|AAB21330.1| 345|Homo sapiens beta 2-glycoprotein I pro... 97 3e-19
M62839-1|AAA51766.1| 345|Homo sapiens apolipoprotein H protein. 97 3e-19
BC026283-1|AAH26283.1| 345|Homo sapiens apolipoprotein H (beta-... 97 3e-19
BC020703-1|AAH20703.1| 345|Homo sapiens apolipoprotein H (beta-... 97 3e-19
AY322156-1|AAP72014.1| 345|Homo sapiens apolipoprotein H (beta-... 97 3e-19
S51940-1|AAB24802.1| 369|Homo sapiens membrane cofactor protein... 97 4e-19
EF076056-1|ABK81636.1| 369|Homo sapiens CD46 protein. 97 4e-19
D84105-1|BAA12224.1| 349|Homo sapiens CD46 protein. 97 4e-19
AL365178-8|CAH73954.1| 349|Homo sapiens CD46 molecule, compleme... 97 4e-19
AL365178-6|CAH73953.1| 369|Homo sapiens CD46 molecule, compleme... 97 4e-19
AL365178-1|CAH73949.1| 362|Homo sapiens CD46 molecule, compleme... 97 4e-19
AL035209-9|CAI18811.1| 349|Homo sapiens CD46 molecule, compleme... 97 4e-19
AL035209-7|CAI18808.1| 369|Homo sapiens CD46 molecule, compleme... 97 4e-19
AL035209-2|CAI18804.1| 362|Homo sapiens CD46 molecule, compleme... 97 4e-19
Y00651-1|CAA68675.1| 384|Homo sapiens protein ( Human mRNA for ... 95 9e-19
M58050-1|AAA62833.1| 377|Homo sapiens membrane cofactor protein... 95 9e-19
EF076055-1|ABK81635.1| 384|Homo sapiens CD46 protein. 95 9e-19
BC030594-1|AAH30594.1| 384|Homo sapiens CD46 molecule, compleme... 95 9e-19
AY916779-1|AAW82433.1| 392|Homo sapiens membrane cofactor prote... 95 9e-19
AL365178-7|CAH73952.1| 399|Homo sapiens CD46 molecule, compleme... 95 9e-19
AL365178-5|CAH73951.1| 384|Homo sapiens CD46 molecule, compleme... 95 9e-19
AL365178-3|CAH73947.1| 392|Homo sapiens CD46 molecule, compleme... 95 9e-19
AL365178-2|CAH73948.1| 377|Homo sapiens CD46 molecule, compleme... 95 9e-19
AL035209-8|CAI18810.1| 399|Homo sapiens CD46 molecule, compleme... 95 9e-19
AL035209-6|CAI18809.1| 384|Homo sapiens CD46 molecule, compleme... 95 9e-19
AL035209-4|CAI18805.1| 392|Homo sapiens CD46 molecule, compleme... 95 9e-19
AL035209-3|CAI18806.1| 377|Homo sapiens CD46 molecule, compleme... 95 9e-19
AK222822-1|BAD96542.1| 399|Homo sapiens membrane cofactor prote... 95 9e-19
AL049744-2|CAI19673.1| 385|Homo sapiens complement factor H pro... 92 9e-18
AL365178-4|CAH73950.1| 336|Homo sapiens CD46 molecule, compleme... 91 2e-17
AL035209-5|CAI18807.1| 336|Homo sapiens CD46 molecule, compleme... 91 2e-17
AL391688-3|CAI41009.1| 465|Homo sapiens sushi-repeat-containing... 89 6e-17
AL035608-3|CAI42847.1| 465|Homo sapiens sushi-repeat-containing... 89 6e-17
AF393649-1|AAM73693.1| 465|Homo sapiens sushi-repeat containing... 89 6e-17
AF060567-1|AAC15765.1| 465|Homo sapiens sushi-repeat protein pr... 89 6e-17
BC126115-1|AAI26116.1| 1024|Homo sapiens seizure related 6 homol... 89 8e-17
AY358405-1|AAQ88771.1| 1023|Homo sapiens SEZ6L protein. 89 8e-17
AL050253-1|CAB43355.1| 792|Homo sapiens hypothetical protein pr... 89 8e-17
AB041736-1|BAB40970.1| 1024|Homo sapiens SEZ6L protein. 89 8e-17
BC020733-1|AAH20733.1| 465|Homo sapiens sushi-repeat-containing... 88 2e-16
AL596218-3|CAI16462.1| 317|Homo sapiens CD55 molecule, decay ac... 87 2e-16
AL391597-3|CAH72947.1| 317|Homo sapiens CD55 molecule, decay ac... 87 2e-16
AL445493-5|CAH70779.1| 181|Homo sapiens complement component 4 ... 87 3e-16
BC109190-1|AAI09191.1| 181|Homo sapiens CR1L protein protein. 85 1e-15
X04481-1|CAA28169.1| 752|Homo sapiens protein ( Human mRNA for ... 85 1e-15
L09708-1|AAB97607.1| 752|Homo sapiens complement component C2 p... 85 1e-15
BX005143-4|CAM25860.1| 752|Homo sapiens complement component 2 ... 85 1e-15
BC043484-1|AAH43484.1| 752|Homo sapiens complement component 2 ... 85 1e-15
BC029781-1|AAH29781.1| 328|Homo sapiens C2 protein protein. 85 1e-15
BA000025-1|BAB63292.1| 577|Homo sapiens C2 protein. 85 1e-15
AY349611-1|AAQ15273.1| 752|Homo sapiens complement component 2 ... 85 1e-15
AL844853-9|CAI41858.1| 752|Homo sapiens complement component 2 ... 85 1e-15
AL844853-8|CAI41857.1| 328|Homo sapiens complement component 2 ... 85 1e-15
AL662849-4|CAI17451.1| 752|Homo sapiens complement component 2 ... 85 1e-15
AL645922-5|CAI41722.1| 752|Homo sapiens complement component 2 ... 85 1e-15
AK222783-1|BAD96503.1| 752|Homo sapiens complement component 2 ... 85 1e-15
AK222537-1|BAD96257.1| 752|Homo sapiens complement component 2 ... 85 1e-15
AF019413-9|AAB67975.1| 752|Homo sapiens complement component C2... 85 1e-15
X72875-1|CAA51389.1| 764|Homo sapiens complement factor B protein. 83 5e-15
X00284-1|CAA25077.1| 244|Homo sapiens protein ( Human mRNA for ... 83 5e-15
S67310-1|AAD13989.1| 764|Homo sapiens complement factor B protein. 83 5e-15
L15702-1|AAA16820.1| 764|Homo sapiens complement factor B protein. 83 5e-15
BX005143-8|CAM25864.1| 764|Homo sapiens complement factor B pro... 83 5e-15
BC007990-1|AAH07990.1| 764|Homo sapiens complement factor B pro... 83 5e-15
BC004143-1|AAH04143.1| 764|Homo sapiens complement factor B pro... 83 5e-15
AL844853-12|CAI41860.1| 764|Homo sapiens B-factor, properdin pr... 83 5e-15
AL844853-11|CAI41859.1| 621|Homo sapiens B-factor, properdin pr... 83 5e-15
AL662849-6|CAI17456.1| 764|Homo sapiens complement factor B pro... 83 5e-15
AL645922-7|CAI41725.2| 764|Homo sapiens complement factor B pro... 83 5e-15
AK223400-1|BAD97120.1| 764|Homo sapiens complement factor B pre... 83 5e-15
AF551848-1|AAN71991.1| 764|Homo sapiens B-factor, properdin pro... 83 5e-15
AF349679-1|AAK30167.1| 621|Homo sapiens factor B protein. 83 5e-15
AF019413-8|AAB67977.1| 764|Homo sapiens complement factor B pro... 83 5e-15
AJ640130-1|CAG26679.2| 578|Homo sapiens complement factor H-rel... 81 2e-14
M65292-1|AAA35946.1| 330|Homo sapiens factor H homologue protein. 81 3e-14
AY038048-1|AAK71497.1| 996|Homo sapiens SEZ6 protein. 80 5e-14
AK223620-1|BAD97340.1| 994|Homo sapiens seizure related 6 homol... 80 5e-14
AK091522-1|BAC03684.1| 869|Homo sapiens protein ( Homo sapiens ... 80 5e-14
AF502129-1|AAM22213.1| 996|Homo sapiens HSEZ6b protein protein. 80 5e-14
M65293-1|AAA35947.1| 330|Homo sapiens factor H homologue protein. 79 9e-14
BC107771-1|AAI07772.1| 330|Homo sapiens complement factor H-rel... 79 9e-14
BC016755-1|AAH16755.1| 330|Homo sapiens complement factor H-rel... 79 9e-14
AL049741-5|CAB53063.1| 330|Homo sapiens complement factor H-rel... 79 9e-14
X56209-1|CAA39666.1| 327|Homo sapiens FHR-1; complement factor ... 79 1e-13
S82496-1|AAB37379.1| 451|Homo sapiens ETX1 protein. 79 1e-13
AK054913-1|BAB70826.1| 320|Homo sapiens protein ( Homo sapiens ... 78 2e-13
U78093-1|AAB36685.1| 464|Homo sapiens sushi-repeat-containing p... 77 3e-13
S82496-2|AAB37378.1| 464|Homo sapiens X-linked retintis pigment... 77 3e-13
BC030816-1|AAH30816.1| 868|Homo sapiens Unknown (protein for MG... 77 3e-13
BC020684-1|AAH20684.1| 464|Homo sapiens sushi-repeat-containing... 77 3e-13
AL606748-1|CAI95406.1| 464|Homo sapiens sushi-repeat-containing... 77 3e-13
AL592463-1|CAH73557.1| 845|Homo sapiens sushi, von Willebrand f... 77 3e-13
AL354982-1|CAH74138.1| 845|Homo sapiens sushi, von Willebrand f... 77 3e-13
U61374-1|AAB40715.1| 461|Homo sapiens protein ( Human novel pro... 77 3e-13
AY055760-1|AAL25835.1| 419|Homo sapiens decay-accelerating fact... 77 3e-13
AY055759-1|AAL25834.1| 265|Homo sapiens decay-accelerating fact... 77 3e-13
AY055758-1|AAL25833.1| 422|Homo sapiens decay-accelerating fact... 77 3e-13
AK055383-1|BAB70912.1| 475|Homo sapiens protein ( Homo sapiens ... 77 3e-13
AK027870-1|BAB55420.1| 1316|Homo sapiens protein ( Homo sapiens ... 77 5e-13
AC005254-1|AAC25581.1| 315|Homo sapiens PGCN_HUMAN, PARTIAL CDS... 77 5e-13
AB210004-1|BAE06086.1| 1335|Homo sapiens CSPG3 variant protein p... 77 5e-13
AL359979-1|CAI12801.1| 490|Homo sapiens sushi domain containing... 74 3e-12
AL359733-2|CAH73991.1| 490|Homo sapiens sushi domain containing... 74 3e-12
AY367062-1|AAQ67702.1| 138|Homo sapiens E-selectin protein. 73 7e-12
AY358495-1|AAQ88859.1| 490|Homo sapiens YHGM196 protein. 73 7e-12
AF026547-1|AAC80576.1| 1321|Homo sapiens neurocan protein. 73 7e-12
BC078657-1|AAH78657.1| 1627|Homo sapiens pregnancy-associated pl... 71 2e-11
X68280-1|CAA48341.1| 1551|Homo sapiens protein ( H.sapiens PAPP-... 71 2e-11
U28727-1|AAC50543.1| 1627|Homo sapiens pregnancy-associated plas... 71 2e-11
AL691426-1|CAI16715.1| 1627|Homo sapiens pregnancy-associated pl... 71 2e-11
AL353141-1|CAI16083.1| 1627|Homo sapiens pregnancy-associated pl... 71 2e-11
AL137024-5|CAI14281.1| 1627|Homo sapiens pregnancy-associated pl... 71 2e-11
CR456574-1|CAG30460.1| 948|Homo sapiens SEZ6L protein. 71 3e-11
AL078460-1|CAI20266.1| 949|Homo sapiens seizure related 6 homol... 71 3e-11
AL049741-3|CAI19622.1| 271|Homo sapiens complement factor H-rel... 71 3e-11
AL023513-2|CAI19980.1| 949|Homo sapiens seizure related 6 homol... 71 3e-11
AL022337-1|CAI17997.1| 949|Homo sapiens seizure related 6 homol... 71 3e-11
AB023144-1|BAA76771.2| 1001|Homo sapiens KIAA0927 protein protein. 71 3e-11
X15998-1|CAA34128.1| 2409|Homo sapiens protein ( H.sapiens mRNA ... 70 4e-11
U26555-1|AAA67565.1| 1642|Homo sapiens versican V2 core protein ... 70 4e-11
U16306-1|AAA65018.1| 3396|Homo sapiens chondroitin sulfate prote... 70 4e-11
J02814-1|AAA36437.1| 688|Homo sapiens protein ( Human chondroit... 70 4e-11
D32039-1|BAA06801.1| 655|Homo sapiens proteoglycan PG-M(V3) pro... 70 4e-11
BX641036-1|CAE46022.1| 2060|Homo sapiens hypothetical protein pr... 70 4e-11
AB209491-1|BAD92728.1| 3410|Homo sapiens chondroitin sulfate pro... 70 4e-11
K01566-1|AAA36225.2| 677|Homo sapiens MHC serum complement fact... 70 5e-11
BC026282-1|AAH26282.1| 434|Homo sapiens Unknown (protein for IM... 70 5e-11
BC004888-1|AAH04888.1| 290|Homo sapiens sushi domain containing... 69 9e-11
AL359979-2|CAI12802.1| 290|Homo sapiens sushi domain containing... 69 9e-11
AL359733-3|CAH73992.1| 290|Homo sapiens sushi domain containing... 69 9e-11
X17519-2|CAB43537.1| 363|Homo sapiens Leu-8 antigen short form ... 69 1e-10
X17519-1|CAB43536.1| 385|Homo sapiens protein ( Human mRNA for ... 69 1e-10
M32414-1|AAB60700.1| 372|Homo sapiens protein ( Human leukocyte... 68 2e-10
BC020758-1|AAH20758.1| 375|Homo sapiens SELL protein protein. 68 2e-10
AY367061-1|AAQ67701.1| 211|Homo sapiens L-selectin protein. 68 2e-10
AY233976-1|AAO48272.1| 372|Homo sapiens selectin L (lymphocyte ... 68 2e-10
AL021940-1|CAI19356.1| 385|Homo sapiens selectin L (lymphocyte ... 68 2e-10
AJ246000-1|CAB55488.1| 385|Homo sapiens L-selectin protein. 68 2e-10
X16150-1|CAA34275.1| 372|Homo sapiens protein ( Human Lyam-1 mR... 68 2e-10
X16070-1|CAA34203.1| 372|Homo sapiens pln homing receptor protein. 68 2e-10
M25280-1|AAC63053.1| 372|Homo sapiens LNHR protein. 68 2e-10
Y09926-1|CAA71059.1| 686|Homo sapiens MASP-2 protein protein. 67 3e-10
X98400-1|CAA67050.1| 686|Homo sapiens mannan-binding lectin-ass... 67 3e-10
BC060770-1|AAH60770.2| 757|Homo sapiens SUSD1 protein protein. 67 3e-10
AY358746-1|AAQ89106.1| 747|Homo sapiens GRGP2438 protein. 67 3e-10
AL158824-3|CAI12348.2| 705|Homo sapiens sushi domain containing... 67 3e-10
AL158824-2|CAI12347.2| 747|Homo sapiens sushi domain containing... 67 3e-10
AL138756-2|CAI95300.2| 705|Homo sapiens sushi domain containing... 67 3e-10
AL138756-1|CAI95299.2| 747|Homo sapiens sushi domain containing... 67 3e-10
AL137432-1|CAB70735.1| 570|Homo sapiens hypothetical protein pr... 67 3e-10
AL035545-1|CAB37431.1| 716|Homo sapiens hypothetical protein pr... 67 3e-10
AK056704-1|BAB71259.1| 570|Homo sapiens protein ( Homo sapiens ... 67 3e-10
AL138756-3|CAI95301.1| 280|Homo sapiens sushi domain containing... 67 4e-10
AL109811-4|CAI22102.1| 686|Homo sapiens mannan-binding lectin s... 67 4e-10
AF321562-1|AAG50274.1| 686|Homo sapiens MBL-associated serine p... 67 4e-10
BC027971-1|AAH27971.1| 911|Homo sapiens brevican protein. 66 6e-10
BC022938-1|AAH22938.1| 911|Homo sapiens brevican protein. 66 6e-10
BC010571-1|AAH10571.1| 911|Homo sapiens brevican protein. 66 6e-10
BC009117-1|AAH09117.1| 911|Homo sapiens brevican protein. 66 6e-10
AY358372-1|AAQ88738.1| 911|Homo sapiens Brevican Core Pro protein. 66 6e-10
AL590666-18|CAI16352.1| 911|Homo sapiens brevican protein. 66 6e-10
AL365181-12|CAI13056.1| 911|Homo sapiens brevican protein. 66 6e-10
AL137504-1|CAB70776.1| 330|Homo sapiens hypothetical protein pr... 66 6e-10
AF228710-1|AAG23134.1| 911|Homo sapiens chondroitin sulfate pro... 66 6e-10
AB209570-1|BAD92807.1| 850|Homo sapiens brevican isoform 1 vari... 66 6e-10
AF134838-1|AAD30280.1| 1479|Homo sapiens endocytic receptor Endo... 65 1e-09
AF107292-1|AAF14192.1| 1479|Homo sapiens urokinase receptor-asso... 65 1e-09
AB014609-1|BAA31684.2| 1484|Homo sapiens KIAA0709 protein protein. 65 1e-09
X06596-1|CAA29817.1| 688|Homo sapiens complement protein C1s pr... 63 5e-09
M18767-1|AAA51853.1| 688|Homo sapiens C1S protein. 63 5e-09
J04080-1|AAA51852.1| 688|Homo sapiens C1S protein. 63 5e-09
BC056903-1|AAH56903.1| 688|Homo sapiens complement component 1,... 63 5e-09
BC089434-1|AAH89434.1| 737|Homo sapiens regeneration associated... 62 1e-08
AY358346-1|AAQ88712.1| 720|Homo sapiens ELGC699 protein. 62 1e-08
AK027841-1|BAB55404.1| 737|Homo sapiens protein ( Homo sapiens ... 62 1e-08
X17406-1|CAA35463.1| 600|Homo sapiens cartilage specific proteo... 61 2e-08
M31241-1|AAD15289.1| 162|Homo sapiens complement receptor 1 pro... 61 2e-08
J05062-1|AAA35726.1| 480|Homo sapiens protein ( Human cartilage... 61 2e-08
BC032313-1|AAH32313.1| 215|Homo sapiens C-type lectin domain fa... 61 2e-08
AY486483-1|AAS59162.1| 215|Homo sapiens C-type lectin variant 2... 61 2e-08
AY486482-1|AAS59161.1| 215|Homo sapiens C-type lectin variant 1... 61 2e-08
AY297446-1|AAQ63173.1| 215|Homo sapiens C-type calcium dependen... 61 2e-08
AY115592-1|AAM75389.1| 215|Homo sapiens C-type lectin-like rece... 61 2e-08
AF411850-1|AAL37713.1| 215|Homo sapiens C-type lectin-like rece... 61 2e-08
AL844853-7|CAI41856.1| 203|Homo sapiens complement component 2 ... 61 2e-08
BX248415-2|CAH70075.1| 331|Homo sapiens complement factor H-rel... 60 4e-08
AL139418-2|CAI21980.1| 331|Homo sapiens complement factor H-rel... 60 4e-08
M65294-1|AAA35948.1| 185|Homo sapiens factor H protein. 59 7e-08
BC126986-1|AAI26987.1| 393|Homo sapiens FLJ37440 protein protein. 59 7e-08
AY358174-1|AAQ88541.1| 1169|Homo sapiens CSMD1 protein. 59 1e-07
AK126936-1|BAC86754.1| 783|Homo sapiens protein ( Homo sapiens ... 59 1e-07
AB067477-1|BAB67783.1| 1048|Homo sapiens KIAA1890 protein protein. 59 1e-07
AK094759-1|BAC04416.1| 439|Homo sapiens protein ( Homo sapiens ... 58 1e-07
BC035784-1|AAH35784.1| 439|Homo sapiens hypothetical protein FL... 58 2e-07
AF264715-1|AAG14442.1| 132|Homo sapiens complement receptor typ... 58 2e-07
AC092645-2|AAY14854.1| 439|Homo sapiens unknown protein. 58 2e-07
X98337-1|CAA66980.1| 331|Homo sapiens complement factor H-relat... 58 2e-07
BC074957-1|AAH74957.1| 331|Homo sapiens complement factor H-rel... 58 2e-07
BC126987-1|AAI26988.1| 305|Homo sapiens FLJ37440 protein protein. 57 3e-07
BC058009-1|AAH58009.1| 330|Homo sapiens complement factor H-rel... 57 3e-07
AL049741-1|CAB53064.1| 330|Homo sapiens complement factor H-rel... 57 3e-07
AF264716-1|AAG14443.1| 132|Homo sapiens complement receptor typ... 57 3e-07
AF169970-1|AAG09140.1| 132|Homo sapiens complement receptor 1 p... 57 4e-07
AF169969-1|AAG09139.1| 132|Homo sapiens complement receptor 1 p... 57 4e-07
X64877-1|CAA46096.1| 270|Homo sapiens serum protein protein. 56 7e-07
U17033-1|AAA70110.1| 1465|Homo sapiens 180 kDa transmembrane PLA... 56 7e-07
BX248415-1|CAH70074.1| 331|Homo sapiens complement factor H-rel... 56 7e-07
BC022283-1|AAH22283.1| 270|Homo sapiens complement factor H-rel... 56 7e-07
AL139418-3|CAI21981.1| 331|Homo sapiens complement factor H-rel... 56 7e-07
AL139418-1|CAI21979.1| 270|Homo sapiens complement factor H-rel... 56 7e-07
M93221-1|AAA60389.1| 1456|Homo sapiens mannose receptor protein. 56 9e-07
J05550-1|AAA59868.1| 1456|Homo sapiens M6PR protein. 56 9e-07
DQ663787-1|ABG47462.1| 1456|Homo sapiens mannose receptor protein. 56 9e-07
BX255924-1|CAI15339.1| 1456|Homo sapiens mannose receptor, C typ... 56 9e-07
BX005143-1|CAM25857.1| 139|Homo sapiens complement component 2 ... 56 9e-07
AL928729-2|CAH70733.1| 1456|Homo sapiens mannose receptor, C typ... 56 9e-07
AL928580-1|CAH71176.1| 1456|Homo sapiens mannose receptor, C typ... 56 9e-07
AL662849-1|CAI17454.2| 139|Homo sapiens complement component 2 ... 56 9e-07
AL645922-2|CAI41721.2| 139|Homo sapiens complement component 2 ... 56 9e-07
AL139238-2|CAH70872.1| 1456|Homo sapiens mannose receptor, C typ... 56 9e-07
AC093873-2|AAY24190.1| 495|Homo sapiens unknown protein. 56 9e-07
Y18287-2|CAB50735.1| 686|Homo sapiens MASP-2 protein. 55 2e-06
Y18286-2|CAB50733.1| 686|Homo sapiens MASP-2 protein protein. 55 2e-06
X72177-1|CAA50994.1| 934|Homo sapiens complement component C6 p... 55 2e-06
M98457-1|AAF77072.1| 404|Homo sapiens membrane-associated lecti... 55 2e-06
J05064-1|AAA51860.1| 934|Homo sapiens C6 protein. 55 2e-06
J05024-1|AAA59668.1| 934|Homo sapiens completement component C6... 55 2e-06
BC110615-1|AAI10616.1| 380|Homo sapiens CD209 protein protein. 55 2e-06
BC035723-1|AAH35723.1| 934|Homo sapiens C6 protein protein. 55 2e-06
AY042231-1|AAK91856.1| 334|Homo sapiens sDC-SIGN1B type II isof... 55 2e-06
AY042230-1|AAK91855.1| 380|Homo sapiens sDC-SIGN1B type I isofo... 55 2e-06
AY042229-1|AAK91854.1| 404|Homo sapiens mDC-SIGN1B type I isofo... 55 2e-06
AY042227-1|AAK91852.1| 268|Homo sapiens sDC-SIGN1A type III iso... 55 2e-06
AY042226-1|AAK91851.1| 360|Homo sapiens sDC-SIGN1A TYPE II isof... 55 2e-06
AY042225-1|AAK91850.1| 380|Homo sapiens sDC-SIGN1A type I isofo... 55 2e-06
AY042223-1|AAK91848.1| 312|Homo sapiens mDC-SIGN1A type III iso... 55 2e-06
AY042221-1|AAK91846.1| 404|Homo sapiens mDC-SIGN1A type I isofo... 55 2e-06
AK074062-1|BAB84888.1| 1282|Homo sapiens FLJ00133 protein protein. 55 2e-06
AF439717-1|AAQ04558.1| 1008|Homo sapiens insulin responsive sequ... 55 2e-06
AF290886-1|AAK20997.1| 404|Homo sapiens DC-SIGN protein. 55 2e-06
AF209479-1|AAG13814.1| 404|Homo sapiens probable mannose-bindin... 55 2e-06
AF099148-1|AAC98508.1| 961|Homo sapiens GABA-B1a receptor protein. 55 2e-06
AB126592-1|BAD02321.1| 934|Homo sapiens complement component 6 ... 55 2e-06
M27190-1|AAA60546.1| 166|Homo sapiens pancreatic stone protein ... 54 2e-06
M18963-1|AAA36558.1| 166|Homo sapiens protein ( Human islet of ... 54 2e-06
BC005350-1|AAH05350.1| 166|Homo sapiens regenerating islet-deri... 54 2e-06
AL596254-1|CAH71731.1| 1791|Homo sapiens pappalysin 2 protein. 54 2e-06
AL139282-1|CAI19567.1| 1791|Homo sapiens pappalysin 2 protein. 54 2e-06
AL031734-1|CAI22172.1| 1791|Homo sapiens pappalysin 2 protein. 54 2e-06
AL031290-5|CAI22721.1| 1791|Homo sapiens pappalysin 2 protein. 54 2e-06
AJ278348-1|CAC11134.1| 1624|Homo sapiens pregnancy-associated pl... 54 2e-06
AF342989-1|AAL17779.1| 1790|Homo sapiens pregnancy-associated pl... 54 2e-06
AF311940-1|AAK31073.1| 1791|Homo sapiens pregnancy-associated pl... 54 2e-06
AF172331-1|AAD51330.1| 166|Homo sapiens lithostathine protein. 54 2e-06
AC017004-3|AAX88842.1| 166|Homo sapiens unknown protein. 54 2e-06
AB209369-1|BAD92606.1| 691|Homo sapiens Pappalysin-2 precursorv... 54 2e-06
D61695-1|BAA34864.1| 699|Homo sapiens mannose-binding protein a... 54 3e-06
D28593-1|BAA05928.1| 699|Homo sapiens MASP protein. 54 3e-06
D17525-1|BAA04477.1| 699|Homo sapiens precursor of P100 serine ... 54 3e-06
BC106946-1|AAI06947.1| 728|Homo sapiens mannan-binding lectin s... 54 3e-06
BC106945-1|AAI06946.1| 728|Homo sapiens mannan-binding lectin s... 54 3e-06
BC093693-1|AAH93693.1| 293|Homo sapiens C-type lectin superfami... 54 3e-06
BC093691-1|AAH93691.1| 293|Homo sapiens C-type lectin superfami... 54 3e-06
AY423706-1|AAR84185.1| 293|Homo sapiens LSECtin protein. 54 3e-06
AY358431-1|AAQ88797.1| 293|Homo sapiens DTTR431 protein. 54 3e-06
AL355178-2|CAI23435.1| 426|Homo sapiens CUB and Sushi multiple ... 54 3e-06
AL355178-1|CAI23434.1| 1167|Homo sapiens CUB and Sushi multiple ... 54 3e-06
AL161643-1|CAI23498.1| 1167|Homo sapiens CUB and Sushi multiple ... 54 3e-06
AK127722-1|BAC87101.1| 1167|Homo sapiens protein ( Homo sapiens ... 54 3e-06
AF284421-1|AAK84071.1| 728|Homo sapiens complement factor MASP-... 54 3e-06
AB007617-1|BAA89206.1| 699|Homo sapiens MASP/P100 protein. 54 3e-06
BX000688-9|CAI18606.1| 961|Homo sapiens gamma-aminobutyric acid... 54 4e-06
AY314006-1|AAP79899.1| 1817|Homo sapiens DEC-205/DCL-1 fusion pr... 54 4e-06
AY184222-1|AAN85434.1| 1873|Homo sapiens DEC-205/DCL-1 fusion pr... 54 4e-06
AL662826-10|CAI17390.1| 961|Homo sapiens gamma-aminobutyric aci... 54 4e-06
AL645936-8|CAI18017.1| 961|Homo sapiens gamma-aminobutyric acid... 54 4e-06
AL031983-8|CAA21453.1| 961|Homo sapiens gamma-aminobutyric acid... 54 4e-06
AJ225028-1|CAA12359.1| 961|Homo sapiens GABA-B receptor protein. 54 4e-06
AJ012288-1|CAA09980.1| 961|Homo sapiens GABA-BR1 protein. 54 4e-06
AJ010170-1|CAA09031.1| 930|Homo sapiens gababr1 protein. 54 4e-06
AF301005-1|AAG23962.1| 578|Homo sapiens gamma-aminobutyric acid... 54 4e-06
AF011333-1|AAC17636.1| 1722|Homo sapiens DEC-205 protein. 54 4e-06
AC093873-1|AAY24189.1| 806|Homo sapiens unknown protein. 54 4e-06
J05412-1|AAA36559.1| 166|Homo sapiens protein ( Human regenerat... 53 6e-06
AF064827-1|AAC62622.1| 1722|Homo sapiens gp200-MR6 protein. 53 6e-06
Z92546-1|CAB62953.1| 822|Homo sapiens bK65A6.2 (novel Sushi dom... 52 9e-06
X68679-1|CAA48639.1| 331|Homo sapiens FHR-3; complement Factor ... 52 9e-06
BC033107-1|AAH33107.1| 822|Homo sapiens sushi domain containing... 52 9e-06
AK026431-1|BAB15481.1| 619|Homo sapiens protein ( Homo sapiens ... 52 9e-06
AK023591-1|BAB14617.1| 413|Homo sapiens protein ( Homo sapiens ... 52 1e-05
AJ012185-1|CAA09939.1| 961|Homo sapiens GABAB receptor, subunit... 52 1e-05
X04701-1|CAA28407.1| 705|Homo sapiens protein ( Human mRNA for ... 51 2e-05
M14058-1|AAA51851.1| 705|Homo sapiens C1R protein. 51 2e-05
BC035220-1|AAH35220.1| 705|Homo sapiens complement component 1,... 51 2e-05
AK222491-1|BAD96211.1| 705|Homo sapiens complement component 1,... 51 2e-05
AK222481-1|BAD96201.1| 705|Homo sapiens complement component 1,... 51 2e-05
AB083037-1|BAC19850.2| 705|Homo sapiens r subcomponent of compl... 51 2e-05
AY055757-1|AAL25832.1| 316|Homo sapiens decay-accelerating fact... 51 3e-05
M15059-1|AAA52434.1| 321|Homo sapiens CRPP1 protein. 50 3e-05
M14766-1|AAA52435.1| 321|Homo sapiens CRPP1 protein. 50 3e-05
BC062591-1|AAH62591.1| 321|Homo sapiens Fc fragment of IgE, low... 50 3e-05
BC031871-1|AAH31871.1| 225|Homo sapiens CSMD2 protein protein. 50 3e-05
BC014108-1|AAH14108.1| 321|Homo sapiens Fc fragment of IgE, low... 50 3e-05
AY042224-1|AAK91849.1| 168|Homo sapiens mDC-SIGN1A type IV isof... 50 3e-05
AY042222-1|AAK91847.1| 398|Homo sapiens mDC-SIGN1A type II isof... 50 3e-05
AL139140-1|CAI19066.1| 225|Homo sapiens CUB and Sushi multiple ... 50 3e-05
AK223207-1|BAD96927.1| 321|Homo sapiens Fc fragment of IgE, low... 50 3e-05
X86328-1|CAA60121.1| 820|Homo sapiens complement C7 protein. 50 5e-05
BC063851-1|AAH63851.1| 843|Homo sapiens complement component 7 ... 50 5e-05
AJ245821-1|CAB57951.1| 580|Homo sapiens putative secreted molec... 50 6e-05
J03507-1|AAA51861.1| 843|Homo sapiens C7 protein. 49 8e-05
BC110614-1|AAI10615.1| 387|Homo sapiens CLEC4M protein protein. 49 8e-05
BC038851-1|AAH38851.1| 399|Homo sapiens C-type lectin domain fa... 49 8e-05
AY042240-1|AAK91865.1| 263|Homo sapiens sDC-SIGN2 type III isof... 49 8e-05
AY042238-1|AAK91863.1| 332|Homo sapiens sDC-SIGN2 type I isofor... 49 8e-05
AY042234-1|AAK91859.1| 399|Homo sapiens mDC-SIGN2 type I isofor... 49 8e-05
AL049741-4|CAI19623.1| 147|Homo sapiens complement factor H-rel... 49 8e-05
AF290887-1|AAK20998.1| 376|Homo sapiens L-SIGN protein. 49 8e-05
AF209481-1|AAG13815.2| 399|Homo sapiens probable mannose bindin... 49 8e-05
U17034-1|AAC50163.1| 1326|Homo sapiens protein ( Human soluble P... 48 1e-04
BC009418-1|AAH09418.1| 273|Homo sapiens chondrolectin protein. 48 1e-04
AY358608-1|AAQ88971.1| 273|Homo sapiens CHODL protein. 48 1e-04
AY343913-1|AAR04559.1| 353|Homo sapiens L-SIGN variant protein. 48 1e-04
AL163217-1|CAB90388.1| 184|Homo sapiens putative gene, membrane... 48 1e-04
AF257472-1|AAL05981.1| 273|Homo sapiens transmembrane protein M... 48 1e-04
X04772-1|CAA28465.1| 321|Homo sapiens protein ( Human mRNA for ... 48 2e-04
BC117441-1|AAI17442.1| 237|Homo sapiens C-type lectin domain fa... 48 2e-04
BC117439-1|AAI17440.1| 237|Homo sapiens C-type lectin domain fa... 48 2e-04
BC074874-1|AAH74874.1| 237|Homo sapiens C-type lectin domain fa... 48 2e-04
BC074822-1|AAH74822.1| 237|Homo sapiens C-type lectin domain fa... 48 2e-04
AK022689-1|BAB14181.1| 232|Homo sapiens protein ( Homo sapiens ... 48 2e-04
AK000914-1|BAA91421.1| 236|Homo sapiens protein ( Homo sapiens ... 48 2e-04
AJ133532-1|CAB54001.1| 237|Homo sapiens dendritic cell immunore... 48 2e-04
AF523315-1|AAP43904.1| 236|Homo sapiens chondrolectin variant C... 48 2e-04
AF523314-1|AAP43903.1| 232|Homo sapiens chondrolectin variant C... 48 2e-04
AF328684-1|AAL56016.1| 230|Homo sapiens Fc-epsilon receptor III... 48 2e-04
AF209714-1|AAF73846.1| 158|Homo sapiens membrane cofactor prote... 48 2e-04
AF209713-1|AAF73845.1| 158|Homo sapiens membrane cofactor prote... 48 2e-04
AF209712-1|AAF73844.1| 158|Homo sapiens membrane cofactor prote... 48 2e-04
AF200738-1|AAG35593.1| 204|Homo sapiens C-type lectin DDB27 sho... 48 2e-04
AF109146-1|AAF14348.1| 237|Homo sapiens C-type lectin superfami... 48 2e-04
BX537451-1|CAD97694.1| 159|Homo sapiens hypothetical protein pr... 47 3e-04
BC114338-1|AAI14339.1| 213|Homo sapiens C-type lectin domain fa... 47 3e-04
BC102017-1|AAI02018.1| 213|Homo sapiens C-type lectin domain fa... 47 3e-04
BC102016-1|AAI02017.1| 213|Homo sapiens C-type lectin domain fa... 47 3e-04
BC102015-1|AAI02016.1| 213|Homo sapiens C-type lectin domain fa... 47 3e-04
BC074968-1|AAH74968.1| 213|Homo sapiens C-type lectin domain fa... 47 3e-04
BC074967-1|AAH74967.1| 213|Homo sapiens C-type lectin domain fa... 47 3e-04
BC017089-1|AAH17089.1| 158|Homo sapiens regenerating islet-deri... 47 3e-04
AY358223-1|AAQ88590.1| 213|Homo sapiens CLECSF11 protein. 47 3e-04
AY126670-1|AAM95598.1| 158|Homo sapiens REG-like protein protein. 47 3e-04
AY007243-1|AAG02562.1| 158|Homo sapiens regenerating gene type ... 47 3e-04
AL359752-2|CAI18972.1| 158|Homo sapiens regenerating islet-deri... 47 3e-04
AF345934-1|AAK59869.1| 158|Homo sapiens regenerating gene type ... 47 3e-04
AF325460-1|AAL37359.1| 182|Homo sapiens dendritic lectin b isof... 47 3e-04
AF325459-1|AAL37358.1| 213|Homo sapiens dendritic lectin protein. 47 3e-04
AF293615-1|AAL37036.1| 213|Homo sapiens blood dendritic cell an... 47 3e-04
AF254415-1|AAK48435.1| 158|Homo sapiens gastrointestinal secret... 47 3e-04
AF067800-1|AAF75560.1| 237|Homo sapiens HDCGC13P protein. 47 3e-04
AC080166-1|AAY24052.1| 968|Homo sapiens unknown protein. 47 3e-04
L08010-1|AAA18204.1| 166|Homo sapiens protein ( Homo sapiens re... 47 4e-04
D17291-1|BAA04124.1| 166|Homo sapiens regenerating protein I be... 47 4e-04
>AY210419-1|AAO34702.1| 3501|Homo sapiens CUB and sushi multiple
domains 3 protein.
Length = 3501
Score = 343 bits (842), Expect = 3e-93
Identities = 205/628 (32%), Positives = 290/628 (46%), Gaps = 44/628 (7%)
Query: 346 CQYLPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDK--SRHCKKDGFWSG-- 401
CQ + +CG P N IL DY VG+R+ Y C +G+ L + + C+ DG WS
Sbjct: 2486 CQAI--SCGIPKAPTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHN 2543
Query: 402 APPSCKYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDG 461
P C ++CG L +G+ I +T++G+ A+++C F LVG+ R C G+W
Sbjct: 2544 KTPRCVVISCGELPTPPNGNK--IGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSE 2601
Query: 462 EAPRCLFDWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVP 521
RCL C P + N V + Y C G L GS+ C WSG
Sbjct: 2602 SETRCLAGHCGIPELIVNGQVIGENYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQL 2661
Query: 522 PSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIP 581
PSC V+CG P NG + + F+C Y + G + C + +WS+ P
Sbjct: 2662 PSCVPVSCGHPGSPIYGRTSGNGFN-FNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPP 2720
Query: 582 SCELTSCPEPEVPSGGYMEA---FDYYVHSTINFH-CEAGHKLIGEPNLVCQQDGEWSGD 637
C++ +C +P +P+ E+ + + T+ F+ C G+ L G L+CQ +G+W
Sbjct: 2721 MCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKP 2780
Query: 638 SPTCEYIDCGKLPTLPYGTMELLNGTTH-LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSD 696
P C IDCG P +P + L+G + GS + YSCT L+G RTC WS
Sbjct: 2781 LPECIMIDCGH-PGVPPNAV--LSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHWSG 2837
Query: 697 SSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKG 756
S P C G+ + GH +R N +R + V+Y C+ G
Sbjct: 2838 SQPHCSG-----------DATGTCGDPGTPGH------GSRQESN-FRTKSTVRYACDTG 2879
Query: 757 YKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDEN 816
Y + G TC NG W+G P C+ V CGNPG NGKV TF ++ Y C E
Sbjct: 2880 YILHGSEERTCLANGSWTGRQPECKAVQCGNPGTTANGKVFRIDGTTF-SSSVIYSCMEG 2938
Query: 817 WELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCE 876
+ L G R C NGTWS P C I+C DP I A L +G Y C+
Sbjct: 2939 YILSGPSVRQCTANGTWSGTLPNCTIISCGDPG--IPANG--LRYGDDYVVGQNVSYMCQ 2994
Query: 877 RGY--NLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYY 934
GY L G + RTC G W+G +P C + C +P I NG++ +N +G S+ Y
Sbjct: 2995 PGYTMELNGSRIRTCTINGTWSGVMPTCRAVTCPTPPQISNGRLEGTNFD--WGFSISYI 3052
Query: 935 CLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
C Y+ P + C+ +G WSGE P C
Sbjct: 3053 CSPGYELSFPAVLTCVGNGTWSGEVPQC 3080
Score = 277 bits (679), Expect = 2e-73
Identities = 181/628 (28%), Positives = 259/628 (41%), Gaps = 44/628 (7%)
Query: 349 LPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKY 408
+P +CG P + GN ++ + + C G+++ G C+ + WS PP CK
Sbjct: 2665 VPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKV 2724
Query: 409 VNCG--GLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRC 466
VNC G+ + + T+G Y C + L G+ C G WD P C
Sbjct: 2725 VNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPEC 2784
Query: 467 LFDWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCK- 525
+ C P NA ++ + GS Y+C L G +S TC L G WSG P C
Sbjct: 2785 IMIDCGHPGVPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHWSGSQPHCSG 2844
Query: 526 --YVNCGTP-TIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPS 582
CG P T GS N T S ++ C+ Y L+G+EE C +G W+ P
Sbjct: 2845 DATGTCGDPGTPGHGSRQESNFRTK--STVRYACDTGYILHGSEERTCLANGSWTGRQPE 2902
Query: 583 CELTSCPEPEVPSGGYMEAFDYYVHST-INFHCEAGHKLIGEPNLVCQQDGEWSGDSPTC 641
C+ C P + G + D S+ + + C G+ L G C +G WSG P C
Sbjct: 2903 CKAVQCGNPGTTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNC 2962
Query: 642 EYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNY--RLVGPVRRTCTEEFQWSDSSP 699
I CG P +P + + +G + Y C Y L G RTCT WS P
Sbjct: 2963 TIISCGD-PGIPANGLRYGDDYV-VGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVMP 3020
Query: 700 RCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKV 759
C + C P + S+ R G + G + Y C GY++
Sbjct: 3021 TCRAVTCPTPP---------------------QISNGRLEGTNFDWGFSISYICSPGYEL 3059
Query: 760 IGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWEL 819
++ TC NG WSG P C CG+PG GK + Y + + C+ + L
Sbjct: 3060 SFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQGK--REGKSFIYQSEVSFSCNFPFIL 3117
Query: 820 EGVIRRMCQENGTWSLEPPICKEIT---CPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCE 876
G R+CQ +GTWS P C E T C +P G T +G + C+
Sbjct: 3118 VGSSTRICQADGTWSGSSPHCIEPTQTSCENPGV---PRHGSQNNTFGFQVGSVVQFHCK 3174
Query: 877 RGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCL 936
+G+ L+G TRTC+ W+G P CIP C+ P + V+ G ++ Y C
Sbjct: 3175 KGHLLQGSTTRTCLPDLTWSGIQPECIPHSCKQPETPAHAN-VVGMDLPSHGYTLIYTCQ 3233
Query: 937 SQYQRV-GPFLRKCLDDGRWSGEEPSCE 963
+ G R C D W+G+ P CE
Sbjct: 3234 PGFFLAGGTEHRVCRSDNTWTGKVPICE 3261
Score = 273 bits (669), Expect = 3e-72
Identities = 175/636 (27%), Positives = 258/636 (40%), Gaps = 47/636 (7%)
Query: 347 QYLPPTCGSPDKLLNTTILGNDY-DVGSRIVYKCPEGHMLLGDKSRHCKKDGF----WSG 401
+Y+ C +P+ + I+ + S + + C G L+G S C+K + W
Sbjct: 2422 RYIAFYCSTPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDA 2481
Query: 402 APPSCKYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERT--CGDEGIW 459
P+C+ ++CG +G + D G R Y C + + L T C +G W
Sbjct: 2482 PVPACQAISCGIPKAPTNGGILTTDYLV--GTRVTYFCNDGYRLSSKELTTAVCQSDGTW 2539
Query: 460 D--GEAPRCLFDWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAW 517
+ PRC+ C + P N + GS A +TC+ G +L GS C G W
Sbjct: 2540 SNHNKTPRCVVISCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSGLW 2599
Query: 518 SGVPPSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWS 577
S C +CG P + V I Y + C P + L G+ +C +D WS
Sbjct: 2600 SESETRCLAGHCGIPELIVNGQV-IGENYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWS 2658
Query: 578 YDIPSCELTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGD 637
+PSC SC P P G + + + F C G+ + G CQ + +WS
Sbjct: 2659 GQLPSCVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHP 2718
Query: 638 SPTCEYIDCGK--LPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWS 695
P C+ ++C +P ++ +G G+V+ Y C Y L G C QW
Sbjct: 2719 PPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWD 2778
Query: 696 DSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEK 755
P C I C P V +++S G Y G+ V Y C
Sbjct: 2779 KPLPECIMIDCGHPGVPPNAVLS---------------------GEKYTFGSTVHYSCTG 2817
Query: 756 GYKVIGESLSTCEDNGQWSGTTPTCQ---YVDCGNPGRIENGKVTLPSNATFYGATAFYQ 812
++G+S TC+ NG WSG+ P C CG+PG +G + T +T Y
Sbjct: 2818 KRSLLGQSSRTCQLNGHWSGSQPHCSGDATGTCGDPGTPGHGSRQESNFRT--KSTVRYA 2875
Query: 813 CDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAH 872
CD + L G R C NG+W+ P CK + C +P +G + +
Sbjct: 2876 CDTGYILHGSEERTCLANGSWTGRQPECKAVQCGNPGT---TANGKVFRIDGTTFSSSVI 2932
Query: 873 YQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVE 932
Y C GY L G R C + G W+GT+P C I C PG NG + + G +V
Sbjct: 2933 YSCMEGYILSGPSVRQCTANGTWSGTLPNCTIISCGDPGIPANG--LRYGDDYVVGQNVS 2990
Query: 933 YYCLSQY--QRVGPFLRKCLDDGRWSGEEPSCELAT 966
Y C Y + G +R C +G WSG P+C T
Sbjct: 2991 YMCQPGYTMELNGSRIRTCTINGTWSGVMPTCRAVT 3026
Score = 240 bits (588), Expect = 2e-62
Identities = 174/635 (27%), Positives = 258/635 (40%), Gaps = 46/635 (7%)
Query: 353 CGSPDKLLNTTILGND--YDVGSRIVYKCPEGHMLLGDKSRHCKKDGF--WSGAPPSCKY 408
C P + N IL D +++G I Y+C G L+G+ C+ GAPP C+
Sbjct: 2254 CQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQ- 2312
Query: 409 VNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLF 468
V C D ++ L C + ++ T E + E +
Sbjct: 2313 VLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVE-FFQTEKEFDVL 2371
Query: 469 DWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVN 528
P S ++++G S A NGH + S G G
Sbjct: 2372 QVYDGPNIQSPVLISLSGDY--SSAFNITSNGHEVFLQWSADH--GNNKKGFRIRYIAFY 2427
Query: 529 CGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDG----KWSYDIPSCE 584
C TP +++ S+ ++ C+ + L G VC + W +P+C+
Sbjct: 2428 CSTPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQ 2487
Query: 585 LTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEP--NLVCQQDGEWSGDS--PT 640
SC P+ P+ G + DY V + + + C G++L + VCQ DG WS + P
Sbjct: 2488 AISCGIPKAPTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPR 2547
Query: 641 CEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPR 700
C I CG+LPT P G + T GS ++C + LVG R C WS+S R
Sbjct: 2548 CVVISCGELPTPPNGNK--IGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSESETR 2605
Query: 701 CEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVI 760
C C P + IV+ + +G Y V Y+C G+++I
Sbjct: 2606 CLAGHCGIP----ELIVN-----------------GQVIGENYGYRDTVVYQCNPGFRLI 2644
Query: 761 GESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELE 820
G S+ C+ + WSG P+C V CG+PG G+ + N + + C+ + ++
Sbjct: 2645 GSSVRICQQDHNWSGQLPSCVPVSCGHPGSPIYGRTS--GNGFNFNDVVTFSCNIGYLMQ 2702
Query: 821 GVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYN 880
G + CQ N WS PP+CK + C DP + + + G Y C GY
Sbjct: 2703 GPTKAQCQANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYF 2762
Query: 881 LKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQ 940
L G C GQW+ +P CI IDC PG N V+S FGS+V Y C +
Sbjct: 2763 LFGSSVLICQPNGQWDKPLPECIMIDCGHPGVPPNA--VLSGEKYTFGSTVHYSCTGKRS 2820
Query: 941 RVGPFLRKCLDDGRWSGEEPSCE-LATNEAVDSGT 974
+G R C +G WSG +P C AT D GT
Sbjct: 2821 LLGQSSRTCQLNGHWSGSQPHCSGDATGTCGDPGT 2855
Score = 126 bits (305), Expect = 3e-28
Identities = 73/241 (30%), Positives = 108/241 (44%), Gaps = 7/241 (2%)
Query: 352 TCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNC 411
TC +P ++ N + G ++D G I Y C G+ L C +G WSG P C C
Sbjct: 3026 TCPTPPQISNGRLEGTNFDWGFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQCLPKFC 3085
Query: 412 GGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDW- 470
G P + + +SC F LVG+ R C +G W G +P C+
Sbjct: 3086 GD--PGIPAQGKREGKSFIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQ 3143
Query: 471 --CPDPPAVSNASVTVN-GHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYV 527
C +P + S G + GS+ + C+ GH+L GST+ TC WSG+ P C
Sbjct: 3144 TSCENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECIPH 3203
Query: 528 NCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWL-NGAEELVCNRDGKWSYDIPSCELT 586
+C P + V+ ++G +TC+P ++L G E VC D W+ +P CE
Sbjct: 3204 SCKQPETPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPICEAG 3263
Query: 587 S 587
S
Sbjct: 3264 S 3264
Score = 57.2 bits (132), Expect = 3e-07
Identities = 28/87 (32%), Positives = 47/87 (54%), Gaps = 1/87 (1%)
Query: 571 NRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQ 630
N K Y+ + SC +P +P G D+ + ST++F C++G++L E L+C++
Sbjct: 852 NNGFKIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEK 911
Query: 631 DGEWSGDSPTCEYIDCGKLPTLPYGTM 657
+ WS PTC+ + CG P GT+
Sbjct: 912 NHWWSHPLPTCDAL-CGGDVRGPSGTI 937
Score = 54.8 bits (126), Expect = 2e-06
Identities = 140/626 (22%), Positives = 221/626 (35%), Gaps = 66/626 (10%)
Query: 352 TCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNC 411
+CG P L G+ + + ++C G L+G+KS C+++ WS P C + C
Sbjct: 522 SCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIF-PC 580
Query: 412 GGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNP-ERTCGDEGIWDGEAPRCLFDW 470
G V D +G +C +T++ +P R +D E+ FD+
Sbjct: 581 LSNFAAPMGTVLSPDYPEGYGNN--LNC--IWTIISDPGSRIHLSFNDFDLESQ---FDF 633
Query: 471 CPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVP-PSCKYVNC 529
S S + + S+ N HIL ++ G + + + C
Sbjct: 634 LAVKDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTFGHNEC 693
Query: 530 GTPTIHKGSFVLINGTTTYGSIAQFTCEPDY-WLNGAEELVC-NRDGK--WSYDIPSCEL 585
P I + GS CE + G E + C DGK WS IP C
Sbjct: 694 PDPGIPINA-RRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKCGA 752
Query: 586 TSCPEPEVPSGGYME-AFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYI 644
PSG + + Y ++N CE + EP + E + +
Sbjct: 753 PCGGHFSAPSGVILSPGWPGYYKDSLN--CE--WVIEAEPGHSIKITFERFQTELNYDVL 808
Query: 645 DCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEI 704
+ P L + NG T + + S Y L F+ S
Sbjct: 809 EVHDGPNLLSPLLGSYNG-TQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTY 867
Query: 705 RCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESL 764
C DP + + R +GH + IG+ V + C+ GY++ E
Sbjct: 868 SCLDP--------GIPVHGRRYGH-------------DFSIGSTVSFSCDSGYRLSHEEP 906
Query: 765 STCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIR 824
CE N WS PTC + CG R +G + P FY + C W ++
Sbjct: 907 LLCEKNHWWSHPLPTCDAL-CGGDVRGPSGTILSPGYPEFYPNS--LNC--TWTVDVTHG 961
Query: 825 RMCQEN-GTWSLEPP-----ICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERG 878
+ Q N T+ LE I + + P A++ GS L T++ G +++ +
Sbjct: 962 KGVQFNFHTFHLEDHHDYLLITENGSFTQPLARL-TGSDL---PPTINAGLYGNFRAQLR 1017
Query: 879 YNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQ 938
+ + IS +N T C PG + G + N G ++ + C S
Sbjct: 1018 F-----ISDFSISYEGFNITFSEYNLEPCEDPGIPQYGSRIGFNFG--IGDTLTFSCSSG 1070
Query: 939 YQRVGPFLRKCLDDGR--WSGEEPSC 962
Y+ G CL GR WS P C
Sbjct: 1071 YRLEGTSEIICLGGGRRVWSAPLPRC 1096
Score = 54.0 bits (124), Expect = 3e-06
Identities = 25/74 (33%), Positives = 38/74 (51%), Gaps = 1/74 (1%)
Query: 584 ELTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEY 643
E SC +P P G E + + F C+ G +LIGE ++VCQ++ +WS + P C +
Sbjct: 519 EKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIF 578
Query: 644 IDCGKLPTLPYGTM 657
C P GT+
Sbjct: 579 -PCLSNFAAPMGTV 591
Score = 51.2 bits (117), Expect = 2e-05
Identities = 72/277 (25%), Positives = 107/277 (38%), Gaps = 25/277 (9%)
Query: 586 TSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDG----EWSGDSPTC 641
+SC P VP G + + V I + C G+ L G P L C + W P C
Sbjct: 139 SSCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPIC 198
Query: 642 EYID-CGKLPTLPYGTMELLNGTTHLGSVIQYSCT-TNYRLVGPVRRTCTEEFQWSDSSP 699
D CG G + + + CT T G +FQ +
Sbjct: 199 RAEDACGGTMRGSSGIISSPSFPNEYHN--NADCTWTIVAEPGDTISLIFTDFQMEEKYD 256
Query: 700 RCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKG--Y 757
E I S+P S +++ S+ + L R D + YR G Y+ +K +
Sbjct: 257 YLE-IEGSEPPTIWLSGMNIPPPIISNKNWL-RLHFVTDSNHRYR-GFSAPYQVKKAIDF 313
Query: 758 KVIGESLSTCEDNGQW-----SGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQ 812
K G L +DN G T + C +PG ENGK + S+ + G+T
Sbjct: 314 KSRGFKLFPGKDNSNKFSILNEGGIKTASNL-CPDPGEPENGK-RIGSDFSL-GSTVQLS 370
Query: 813 CDENWELEG----VIRRMCQENGTWSLEPPICKEITC 845
CDE++ L+G +R+ + WS P+CK TC
Sbjct: 371 CDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTC 407
Score = 50.8 bits (116), Expect = 3e-05
Identities = 59/248 (23%), Positives = 99/248 (39%), Gaps = 22/248 (8%)
Query: 349 LPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHC--KKDG--FWSGAPP 404
L +C P ++N T LG DY +GS + Y C G++L G + C DG W+ A P
Sbjct: 1556 LRESCFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALP 1615
Query: 405 SCKYVNCGGLTPIEDGDVALIDNRTTHGARALYSCREN--FTLVGNPERTCGDEGIWDGE 462
SC + CG + +G V L N + YS N +++ E + ++
Sbjct: 1616 SC-HAPCGSRSTGSEGTV-LSPNYPKN-----YSVGHNCVYSIAVPKEFVVFGQFVFFQT 1668
Query: 463 APRCLFDWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGG---AWSG 519
+ + + P S+ +++G +G + N + ++ T G +
Sbjct: 1669 SLHDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVYQA 1728
Query: 520 VPPSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVC----NRDGK 575
VP + P G I GS F C P Y L+G+ + C N +
Sbjct: 1729 VPRTSSTQCSSVPEPRFGR--RIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQ 1786
Query: 576 WSYDIPSC 583
W+ +P+C
Sbjct: 1787 WNDSLPTC 1794
Score = 48.4 bits (110), Expect = 1e-04
Identities = 27/76 (35%), Positives = 37/76 (48%), Gaps = 3/76 (3%)
Query: 584 ELTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQ--DGEWSGDSPTC 641
+L SCP+P G++ D+ V TI+F C G+ LIG L C W+ P C
Sbjct: 2079 QLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRC 2138
Query: 642 EYIDCGKLPTLPYGTM 657
E + CG T GT+
Sbjct: 2139 EAL-CGGNITAMNGTI 2153
Score = 47.6 bits (108), Expect = 2e-04
Identities = 23/57 (40%), Positives = 26/57 (45%), Gaps = 3/57 (5%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
CGHP VPPNA +S E G+ Y C L G R C L G W+ P C
Sbjct: 2789 CGHPGVPPNAVLS---GEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHWSGSQPHC 2842
Score = 47.2 bits (107), Expect = 3e-04
Identities = 22/65 (33%), Positives = 31/65 (47%), Gaps = 3/65 (4%)
Query: 585 LTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQD--GEWSGDSPTCE 642
L SCPEP+ PS G Y V ++F C+ G+ L G ++ C W+ +P C
Sbjct: 1908 LDSCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPTPIC- 1966
Query: 643 YIDCG 647
CG
Sbjct: 1967 LAQCG 1971
Score = 46.4 bits (105), Expect = 6e-04
Identities = 28/88 (31%), Positives = 38/88 (43%), Gaps = 5/88 (5%)
Query: 471 CPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTC----TLGGAWSGVPPSCKY 526
CPDP N + GS +C+ ++L G+ S+TC + AWS P CK
Sbjct: 345 CPDPGEPENGKRIGSDFSLGSTVQLSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKV 404
Query: 527 VNCGTPTI-HKGSFVLINGTTTYGSIAQ 553
CG+ G+F N Y S AQ
Sbjct: 405 KTCGSNLQGPSGTFTSPNFPFQYDSNAQ 432
Score = 46.0 bits (104), Expect = 7e-04
Identities = 23/73 (31%), Positives = 33/73 (45%), Gaps = 4/73 (5%)
Query: 588 CPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGE----WSGDSPTCEY 643
CP+P P G D+ + ST+ C+ + L G ++ CQ+ E WS P C+
Sbjct: 345 CPDPGEPENGKRIGSDFSLGSTVQLSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKV 404
Query: 644 IDCGKLPTLPYGT 656
CG P GT
Sbjct: 405 KTCGSNLQGPSGT 417
Score = 45.6 bits (103), Expect = 0.001
Identities = 107/466 (22%), Positives = 166/466 (35%), Gaps = 57/466 (12%)
Query: 471 CPDPPAVSNASVTVNGHKAGSLASYTCENGHI-LSGSTSVTCTLGGA---WSGVPPSCKY 526
CPDP NA + + GS S CE G I G+ ++TC L WSG+ P C
Sbjct: 693 CPDPGIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKCG- 751
Query: 527 VNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAE-----ELVCNR-DGKWSYDI 580
CG +L G Y CE W+ AE ++ R + +YD+
Sbjct: 752 APCGGHFSAPSGVILSPGWPGYYK-DSLNCE---WVIEAEPGHSIKITFERFQTELNYDV 807
Query: 581 PSCELTSCPEPEVP-SGGYM-EAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDS 638
E+ P P G Y ++ S+ NF + L N + +S
Sbjct: 808 --LEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFI----YLLFTTDNSRSNNGFKIHYES 861
Query: 639 PTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSS 698
T C P +P + + +GS + +SC + YRL C + WS
Sbjct: 862 VTVNTYSCLD-PGIPVHGRRYGHDFS-IGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPL 919
Query: 699 PRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYK 758
P C+ + C + + G + ++L + DV + G V++ +
Sbjct: 920 PTCDAL-CGGDVRGPSGTILSPGYPEFYPNSL-NCTWTVDVTH----GKGVQFNFHTFHL 973
Query: 759 VIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWE 818
+NG S T P + P I G L N + A + D +
Sbjct: 974 EDHHDYLLITENG--SFTQPLARLTGSDLPPTINAG---LYGN---FRAQLRFISDFSIS 1025
Query: 819 LEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERG 878
EG + N LEP C DP + GS + IG + C G
Sbjct: 1026 YEGFNITFSEYN----LEP-------CEDPGIP-QYGSR---IGFNFGIGDTLTFSCSSG 1070
Query: 879 YNLKGHQTRTCISKGQ--WNGTVPVCIPIDCRSPGNIENGKIVISN 922
Y L+G C+ G+ W+ +P C+ +C + G ++ N
Sbjct: 1071 YRLEGTSEIICLGGGRRVWSAPLPRCV-AECGASATNNEGILLSPN 1115
Score = 44.8 bits (101), Expect = 0.002
Identities = 21/58 (36%), Positives = 27/58 (46%), Gaps = 1/58 (1%)
Query: 2 CGHPAVPPNA-RVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C P +P N+ R S N GT+ Y+C+ GY LFG+ C G W P C
Sbjct: 2727 CSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPEC 2784
Score = 44.4 bits (100), Expect = 0.002
Identities = 54/230 (23%), Positives = 82/230 (35%), Gaps = 15/230 (6%)
Query: 739 VGNTYRIGALVKYRCEKGYKVIGESLSTCED--NGQWSGTTPTCQYVDCGNPGRIENGKV 796
+GN + +G + + C GY +IG S TC + W+ P C+ + CG NG +
Sbjct: 2095 IGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEAL-CGGNITAMNGTI 2153
Query: 797 TLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGS 856
P Y F C W + N T PI IT D Q
Sbjct: 2154 YSPGYPDEY--PNFQDC--FWLVRVPPGNGIYINFTVLQTEPIYDFITVWDGPDQNSPQI 2209
Query: 857 GLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENG 916
G + L E+ Y +K H T + G + + C+ P + N
Sbjct: 2210 GQFSGNTAL----ESVYSTSNQILIKFHSDFT--TSGFFVLSYHAYQLRVCQPPPPVPNA 2263
Query: 917 KIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGR--WSGEEPSCEL 964
+I+ + G + Y CL + VG + C R G P C++
Sbjct: 2264 EILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQV 2313
Score = 43.6 bits (98), Expect = 0.004
Identities = 26/93 (27%), Positives = 43/93 (46%), Gaps = 4/93 (4%)
Query: 333 NDVGCNLDYLHWICQ-YLPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSR 391
+D N H + Q Y +C P N ++GND+ VG I ++C G+ L+G+ +
Sbjct: 2062 SDYSQNKQGFHIVYQAYQLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSAL 2121
Query: 392 HCKK--DGFWSGAPPSCKYVNCGGLTPIEDGDV 422
C W+ P C+ + CGG +G +
Sbjct: 2122 TCLHGVSRNWNHPLPRCEAL-CGGNITAMNGTI 2153
Score = 42.3 bits (95), Expect = 0.009
Identities = 20/57 (35%), Positives = 24/57 (42%), Gaps = 3/57 (5%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
CG P P + E N + Y CD GY L G+ +R C G WT P C
Sbjct: 2850 CGDPGTPGHGS---RQESNFRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQPEC 2903
Score = 41.9 bits (94), Expect = 0.012
Identities = 22/59 (37%), Positives = 29/59 (49%), Gaps = 5/59 (8%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGY--ELFGARQRECTLRGDWTLEPPFC 58
CG P +P N + ++ V G Y C GY EL G+R R CT+ G W+ P C
Sbjct: 2967 CGDPGIPANG---LRYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVMPTC 3022
Score = 41.5 bits (93), Expect = 0.016
Identities = 22/64 (34%), Positives = 33/64 (51%), Gaps = 4/64 (6%)
Query: 353 CGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKK--DGF--WSGAPPSCKY 408
C P + N +G+D+ +GS + C E ++L G KS C++ + F WS P CK
Sbjct: 345 CPDPGEPENGKRIGSDFSLGSTVQLSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKV 404
Query: 409 VNCG 412
CG
Sbjct: 405 KTCG 408
Score = 41.5 bits (93), Expect = 0.016
Identities = 49/229 (21%), Positives = 79/229 (34%), Gaps = 16/229 (6%)
Query: 739 VGNTYRIGALVKYRCEKGYKVIGESLSTCEDN--GQWSGTTPTCQYVDCGNPGRIENGKV 796
+G+ Y +G +V ++C++GY + G S TC +W+ TP C CG +G +
Sbjct: 1923 IGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPTPIC-LAQCGGAMSDFSGVI 1981
Query: 797 TLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGS 856
P Y ++ N + + T ++ + + S I S
Sbjct: 1982 LSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLS 2041
Query: 857 GLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENG 916
G + +S S E Y+ Q C P NG
Sbjct: 2042 GPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQ---------SCPDPRPFRNG 2092
Query: 917 KIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLD--DGRWSGEEPSCE 963
VI N T+ G ++ + C Y +G CL W+ P CE
Sbjct: 2093 -FVIGNDFTV-GQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCE 2139
Score = 41.1 bits (92), Expect = 0.021
Identities = 49/223 (21%), Positives = 81/223 (36%), Gaps = 15/223 (6%)
Query: 432 GARALYSCRENFTLVGNPERTC--GDEGIWDGEAPRCLFDWCPDPPAVSNASVTVN-GHK 488
G +SC + L G E C G +W PRC+ + C A +N + ++ +
Sbjct: 1060 GDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVAE-C-GASATNNEGILLSPNYP 1117
Query: 489 AGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTIHK-GSFVLINGTTT 547
++ C + + + K + T H G+F G +
Sbjct: 1118 LNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDGKDKTTHLLGAFT---GASM 1174
Query: 548 YGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGY-MEAFDYYV 606
G T WL + +G + S EL+ C +P +P GY + ++
Sbjct: 1175 RGLTLSSTSN-QLWLEFNSDTEGTDEG-FQLVYTSFELSHCEDPGIPQFGYKISDQGHFA 1232
Query: 607 HSTINFHCEAGHKLIGEPNLVCQ--QDGEWSGDSPTCEYIDCG 647
STI + C G+ L G L C + W P+C +CG
Sbjct: 1233 GSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSC-IAECG 1274
Score = 41.1 bits (92), Expect = 0.021
Identities = 25/75 (33%), Positives = 36/75 (48%), Gaps = 5/75 (6%)
Query: 587 SCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVC--QQDGE--WSGDSPTCE 642
SC +P G DY + ST+ ++C+AG+ L G L C DG W+ P+C
Sbjct: 1559 SCFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSC- 1617
Query: 643 YIDCGKLPTLPYGTM 657
+ CG T GT+
Sbjct: 1618 HAPCGSRSTGSEGTV 1632
Score = 41.1 bits (92), Expect = 0.021
Identities = 22/66 (33%), Positives = 35/66 (53%), Gaps = 5/66 (7%)
Query: 739 VGNTYRIGALVKYRCEKGYKVIGESLSTC--EDNGQ--WSGTTPTCQYVDCGNPGRIENG 794
+G Y++G+ V Y C+ GY + G S TC D+G+ W+ P+C + CG+ G
Sbjct: 1572 LGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSC-HAPCGSRSTGSEG 1630
Query: 795 KVTLPS 800
V P+
Sbjct: 1631 TVLSPN 1636
Score = 41.1 bits (92), Expect = 0.021
Identities = 19/62 (30%), Positives = 34/62 (54%), Gaps = 6/62 (9%)
Query: 844 TCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCI--SKGQWNGTVPV 901
+CP+P SG+ + + +G +QC++GY+L+GH TC+ +WN P+
Sbjct: 1910 SCPEPQTP---SSGIKIGDRYM-VGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPTPI 1965
Query: 902 CI 903
C+
Sbjct: 1966 CL 1967
Score = 41.1 bits (92), Expect = 0.021
Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 9/77 (11%)
Query: 471 CPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGA--WSGVPPSCKYVN 528
CPDP N V N G S+ C G+ L G++++TC G + W+ P C+ +
Sbjct: 2083 CPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEAL- 2141
Query: 529 CGTPTIHKGSFVLINGT 545
CG G+ +NGT
Sbjct: 2142 CG------GNITAMNGT 2152
Score = 41.1 bits (92), Expect = 0.021
Identities = 23/77 (29%), Positives = 35/77 (45%), Gaps = 3/77 (3%)
Query: 1 RCGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGT 60
+CG+P N +V + + +Y C EGY L G R+CT G W+ P C T
Sbjct: 2907 QCGNPGTTANGKVF--RIDGTTFSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNC-T 2963
Query: 61 NVAFRKPANQSTTVRGG 77
++ P + +R G
Sbjct: 2964 IISCGDPGIPANGLRYG 2980
Score = 39.5 bits (88), Expect = 0.064
Identities = 19/64 (29%), Positives = 30/64 (46%), Gaps = 3/64 (4%)
Query: 469 DWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGA--WSGVPPSCKY 526
D CP+P S+ + + G + S+ C+ G+ L G + +TC G W+ P C
Sbjct: 1909 DSCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPTPIC-L 1967
Query: 527 VNCG 530
CG
Sbjct: 1968 AQCG 1971
Score = 37.9 bits (84), Expect = 0.20
Identities = 24/88 (27%), Positives = 43/88 (48%), Gaps = 9/88 (10%)
Query: 343 HWICQYLPPT----CGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCK---- 394
H++ Q +P T C S + +GN++ VGS +++ C G++L G + C+
Sbjct: 1723 HFVYQAVPRTSSTQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPN 1782
Query: 395 KDGFWSGAPPSCKYVNCGGLTPIEDGDV 422
W+ + P+C V CGG+ G +
Sbjct: 1783 SLAQWNDSLPTC-IVPCGGILTKRKGTI 1809
Score = 37.9 bits (84), Expect = 0.20
Identities = 21/67 (31%), Positives = 30/67 (44%), Gaps = 5/67 (7%)
Query: 737 RDVGNTYRIGALVKYRCEKGYKVIGESLSTCE----DNGQWSGTTPTCQYVDCGNPGRIE 792
R +GN + +G+ V + C GY + G CE QW+ + PTC V CG
Sbjct: 1747 RRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTC-IVPCGGILTKR 1805
Query: 793 NGKVTLP 799
G + P
Sbjct: 1806 KGTILSP 1812
Score = 37.9 bits (84), Expect = 0.20
Identities = 23/82 (28%), Positives = 33/82 (40%), Gaps = 4/82 (4%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTN 61
CGHP P R S N N + + C+ GY + G + +C W+ PP C
Sbjct: 2669 CGHPGSPIYGRTS-GNGFNF--NDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKV- 2724
Query: 62 VAFRKPANQSTTVRGGAAANGN 83
V P + + R +GN
Sbjct: 2725 VNCSDPGIPANSKRESKIEHGN 2746
Score = 37.5 bits (83), Expect = 0.26
Identities = 21/83 (25%), Positives = 40/83 (48%), Gaps = 6/83 (7%)
Query: 735 DNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQ----WSGTTPTCQYVDCGNPGR 790
+ + +G+ + +G+ V+ C++ Y + G TC+ + WS P C+ CG+ +
Sbjct: 353 NGKRIGSDFSLGSTVQLSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQ 412
Query: 791 IENGKVTLPSNATFYGATAFYQC 813
+G T P+ Y + A QC
Sbjct: 413 GPSGTFTSPNFPFQYDSNA--QC 433
Score = 37.5 bits (83), Expect = 0.26
Identities = 20/62 (32%), Positives = 31/62 (50%), Gaps = 5/62 (8%)
Query: 542 INGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGK----WSYDIPSCELTSC-PEPEVPSG 596
I + GS Q +C+ DY L GA+ + C R + WS P C++ +C + PSG
Sbjct: 357 IGSDFSLGSTVQLSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSG 416
Query: 597 GY 598
+
Sbjct: 417 TF 418
Score = 37.5 bits (83), Expect = 0.26
Identities = 19/51 (37%), Positives = 26/51 (50%), Gaps = 5/51 (9%)
Query: 867 IGGEAHYQCERGYNLKGHQTRTCI----SKGQWNGTVPVC-IPIDCRSPGN 912
+G Y C+ GY L+G+ T TCI + WN +P C P RS G+
Sbjct: 1578 LGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCGSRSTGS 1628
Score = 36.7 bits (81), Expect = 0.45
Identities = 26/85 (30%), Positives = 37/85 (43%), Gaps = 9/85 (10%)
Query: 844 TCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISK----GQWNGTV 899
+C +P K G+L T +G + Y C GY L GH TCI+ W+ V
Sbjct: 140 SCGNPGVPPK---GVLYGTR-FDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPV 195
Query: 900 PVCIPIDCRSPGNIENGKIVISNGS 924
P+C D G + +IS+ S
Sbjct: 196 PICRAEDA-CGGTMRGSSGIISSPS 219
Score = 36.7 bits (81), Expect = 0.45
Identities = 19/57 (33%), Positives = 27/57 (47%), Gaps = 3/57 (5%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
CG PPN I + + G+ A++ CD G+ L G+ REC G W+ C
Sbjct: 2553 CGELPTPPNGN-KIGTQTSY--GSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRC 2606
Score = 36.3 bits (80), Expect = 0.60
Identities = 20/65 (30%), Positives = 27/65 (41%), Gaps = 4/65 (6%)
Query: 586 TSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGE---WSGDSPTCE 642
T+C +P VP G T+ F C+ G++L GE + C Q W P C
Sbjct: 1385 TACRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVC- 1443
Query: 643 YIDCG 647
CG
Sbjct: 1444 IAPCG 1448
Score = 36.3 bits (80), Expect = 0.60
Identities = 24/60 (40%), Positives = 30/60 (50%), Gaps = 6/60 (10%)
Query: 907 CRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCL--DDGR--WSGEEPSC 962
C PGNI NG + + GS+V YYC + Y G C+ DDGR W+ PSC
Sbjct: 1560 CFDPGNIMNGTRLGMDYK--LGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSC 1617
Score = 35.5 bits (78), Expect = 1.0
Identities = 20/67 (29%), Positives = 30/67 (44%), Gaps = 5/67 (7%)
Query: 352 TCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGF----WSGAPPSCK 407
+CG+P + G +DVG +I Y C G++L G C + W P C+
Sbjct: 140 SCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICR 199
Query: 408 YVN-CGG 413
+ CGG
Sbjct: 200 AEDACGG 206
Score = 35.5 bits (78), Expect = 1.0
Identities = 22/82 (26%), Positives = 35/82 (42%), Gaps = 5/82 (6%)
Query: 580 IPSCELTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQ----QDGEWS 635
+P T C P G ++ V S++ F C G+ L G + C+ +W+
Sbjct: 1729 VPRTSSTQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWN 1788
Query: 636 GDSPTCEYIDCGKLPTLPYGTM 657
PTC + CG + T GT+
Sbjct: 1789 DSLPTC-IVPCGGILTKRKGTI 1809
Score = 35.1 bits (77), Expect = 1.4
Identities = 21/60 (35%), Positives = 25/60 (41%), Gaps = 6/60 (10%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTL---RGDWTLEPPFC 58
C P VP N N + G V++CD GYEL G + C R W PP C
Sbjct: 1387 CRDPGVPMNGT---RNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVC 1443
Score = 35.1 bits (77), Expect = 1.4
Identities = 20/59 (33%), Positives = 27/59 (45%), Gaps = 5/59 (8%)
Query: 785 CGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMC---QENGTWSLEPPIC 840
C +PG NG T + G T +QCD +EL+G R C + W PP+C
Sbjct: 1387 CRDPGVPMNG--TRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVC 1443
Score = 34.7 bits (76), Expect = 1.8
Identities = 20/74 (27%), Positives = 28/74 (37%), Gaps = 4/74 (5%)
Query: 471 CPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTL---GGAWSGVPPSCKYV 527
C DP N + +G + G + C+ G+ L G +TC W PP C
Sbjct: 1387 CRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVC-IA 1445
Query: 528 NCGTPTIHKGSFVL 541
CG F+L
Sbjct: 1446 PCGGNLTGSSGFIL 1459
Score = 34.7 bits (76), Expect = 1.8
Identities = 19/59 (32%), Positives = 25/59 (42%), Gaps = 3/59 (5%)
Query: 528 NCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVC--NRDGKWSYDIPSCE 584
+C P + FV+ N T G F C P Y L G L C W++ +P CE
Sbjct: 2082 SCPDPRPFRNGFVIGNDFTV-GQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCE 2139
Score = 33.5 bits (73), Expect = 4.2
Identities = 24/83 (28%), Positives = 35/83 (42%), Gaps = 4/83 (4%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTN 61
CG P + N +V EN VY+C+ G+ L G+ R C +W+ + P C
Sbjct: 2611 CGIPELIVNGQVI---GENYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSC-VP 2666
Query: 62 VAFRKPANQSTTVRGGAAANGND 84
V+ P + G N ND
Sbjct: 2667 VSCGHPGSPIYGRTSGNGFNFND 2689
Score = 33.1 bits (72), Expect = 5.6
Identities = 15/39 (38%), Positives = 22/39 (56%), Gaps = 3/39 (7%)
Query: 868 GGEAHYQCERGYNLKGHQTRTCI---SKGQWNGTVPVCI 903
G +QC+ GY L+G + TCI ++ W + PVCI
Sbjct: 1406 GDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCI 1444
Score = 33.1 bits (72), Expect = 5.6
Identities = 20/59 (33%), Positives = 26/59 (44%), Gaps = 4/59 (6%)
Query: 410 NCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTC--GDEGIWDGEAPRC 466
+C P +G V I N T G + C +TL+GN TC G W+ PRC
Sbjct: 2082 SCPDPRPFRNGFV--IGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRC 2138
>AB114605-1|BAC82444.1| 3667|Homo sapiens CSMD3 protein isoform 2
protein.
Length = 3667
Score = 335 bits (823), Expect = 6e-91
Identities = 195/625 (31%), Positives = 272/625 (43%), Gaps = 42/625 (6%)
Query: 346 CQYLPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPS 405
CQ + +CG N +G GS ++ C G ML+G R C G WS +
Sbjct: 2714 CQII--SCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSESETR 2771
Query: 406 CKYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPR 465
C +CG I +G V I + +Y C F L+G+ R C + W G+ P
Sbjct: 2772 CLAGHCGIPELIVNGQV--IGENYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPS 2829
Query: 466 CLFDWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCK 525
C+ C P + + NG + +++C G+++ G T C WS PP CK
Sbjct: 2830 CVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCK 2889
Query: 526 YVNC---GTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPS 582
VNC G P K + +G TYG++ + C P Y+L G+ L+C +G+W +P
Sbjct: 2890 VVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPE 2949
Query: 583 CELTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCE 642
C + C P VP + Y ST+++ C L+G+ + CQ +G WSG P C
Sbjct: 2950 CIMIDCGHPGVPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHWSGSQPHCS 3009
Query: 643 ---YIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSP 699
CG T +G+ + N T S ++Y+C T Y L G RTC W+ P
Sbjct: 3010 GDATGTCGDPGTPGHGSRQESNFRTK--STVRYACDTGYILHGSEERTCLANGSWTGRQP 3067
Query: 700 RCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKV 759
C+ ++C +P T N + R G T+ + V Y C +GY +
Sbjct: 3068 ECKAVQCGNP--------GTTANGKVF----------RIDGTTF--SSSVIYSCMEGYIL 3107
Query: 760 IGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENW-- 817
G S+ C NG WSGT P C + CG+PG NG + G Y C +
Sbjct: 3108 SGPSVRQCTANGTWSGTLPNCTIISCGDPGIPANG--LRYGDDYVVGQNVSYMCQPGYTM 3165
Query: 818 ELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCER 877
EL G R C NGTWS P C+ +TCP P QI G + + G Y C
Sbjct: 3166 ELNGSRIRTCTINGTWSGVMPTCRAVTCPTP-PQISNGR---LEGTNFDWGFSISYICSP 3221
Query: 878 GYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLS 937
GY L TC+ G W+G VP C+P C PG GK S ++ S V + C
Sbjct: 3222 GYELSFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQGK--REGKSFIYQSEVSFSCNF 3279
Query: 938 QYQRVGPFLRKCLDDGRWSGEEPSC 962
+ VG R C DG WSG P C
Sbjct: 3280 PFILVGSSTRICQADGTWSGSSPHC 3304
Score = 333 bits (819), Expect = 2e-90
Identities = 195/606 (32%), Positives = 280/606 (46%), Gaps = 40/606 (6%)
Query: 366 GNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWS--GAPPSCKYVNCGGLTPIEDGDVA 423
G+ Y+ +++V+ C G+ LG S C +G WS P C+ ++CG L +G+
Sbjct: 2672 GSHYEYKTKVVFSCDPGYHGLGPASIECLPNGTWSWRNERPYCQIISCGELPTPPNGNK- 2730
Query: 424 LIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVT 483
I +T++G+ A+++C F LVG+ R C G+W RCL C P + N V
Sbjct: 2731 -IGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRCLAGHCGIPELIVNGQVI 2789
Query: 484 VNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTIHKGSFVLIN 543
+ Y C G L GS+ C WSG PSC V+CG P N
Sbjct: 2790 GENYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGHPGSPIYGRTSGN 2849
Query: 544 GTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEA-- 601
G + + F+C Y + G + C + +WS+ P C++ +C +P +P+ E+
Sbjct: 2850 GFN-FNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGIPANSKRESKI 2908
Query: 602 -FDYYVHSTINFH-CEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMEL 659
+ + T+ F+ C G+ L G L+CQ +G+W P C IDCG P +P +
Sbjct: 2909 EHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGH-PGVPPNAV-- 2965
Query: 660 LNGTTH-LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVS 718
L+G + GS + YSCT L+G RTC WS S P C
Sbjct: 2966 LSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHWSGSQPHCSG-----------DATG 3014
Query: 719 VTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTP 778
G+ + GH +R N +R + V+Y C+ GY + G TC NG W+G P
Sbjct: 3015 TCGDPGTPGH------GSRQESN-FRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQP 3067
Query: 779 TCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPP 838
C+ V CGNPG NGKV TF ++ Y C E + L G R C NGTWS P
Sbjct: 3068 ECKAVQCGNPGTTANGKVFRIDGTTF-SSSVIYSCMEGYILSGPSVRQCTANGTWSGTLP 3126
Query: 839 ICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGY--NLKGHQTRTCISKGQWN 896
C I+C DP I A L +G Y C+ GY L G + RTC G W+
Sbjct: 3127 NCTIISCGDPG--IPANG--LRYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTINGTWS 3182
Query: 897 GTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWS 956
G +P C + C +P I NG++ +N +G S+ Y C Y+ P + C+ +G WS
Sbjct: 3183 GVMPTCRAVTCPTPPQISNGRLEGTNFD--WGFSISYICSPGYELSFPAVLTCVGNGTWS 3240
Query: 957 GEEPSC 962
GE P C
Sbjct: 3241 GEVPQC 3246
Score = 307 bits (754), Expect = 1e-82
Identities = 195/638 (30%), Positives = 279/638 (43%), Gaps = 50/638 (7%)
Query: 347 QYLPPTCGSPDKLLNTTILGNDY-DVGSRIVYKCPEGHMLLGDKSRHCKKDGF----WSG 401
+Y+ C +P+ + I+ + S + + C G L+G S C+K + W
Sbjct: 2523 RYIAFYCSTPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDA 2582
Query: 402 APPSCKYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERT--CGDEGIW 459
P+C+ ++CG +G + D G R Y C + + L T C +G W
Sbjct: 2583 PVPACQAISCGIPKAPTNGGILTTDYLV--GTRVTYFCNDGYRLSSKELTTAVCQSDGTW 2640
Query: 460 D--GEAPRCLFDWCPDPPAV---SNASVTVNG--HKAGSLASYTCENGHILSGSTSVTCT 512
+ PRC+ CP + VNG ++ + ++C+ G+ G S+ C
Sbjct: 2641 SNHNKTPRCVVVTCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECL 2700
Query: 513 LGGAWS--GVPPSCKYVNCG-TPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELV 569
G WS P C+ ++CG PT G+ I T+YGS A FTC+ + L G+
Sbjct: 2701 PNGTWSWRNERPYCQIISCGELPTPPNGN--KIGTQTSYGSTAIFTCDLGFMLVGSAVRE 2758
Query: 570 CNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQ 629
C G WS C C PE+ G + +Y T+ + C G +LIG +CQ
Sbjct: 2759 CLSSGLWSESETRCLAGHCGIPELIVNGQVIGENYGYRDTVVYQCNPGFRLIGSSVRICQ 2818
Query: 630 QDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCT 689
QD WSG P+C + CG + YG NG + V+ +SC Y + GP + C
Sbjct: 2819 QDHNWSGQLPSCVPVSCGHPGSPIYGRTS-GNG-FNFNDVVTFSCNIGYLMQGPTKAQCQ 2876
Query: 690 EEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALV 749
QWS P C+ + CSDP + S + + GN + G +V
Sbjct: 2877 ANRQWSHPPPMCKVVNCSDPGIPANS----------------KRESKIEHGN-FTYGTVV 2919
Query: 750 KYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATA 809
Y C GY + G S+ C+ NGQW P C +DCG+PG N L +G+T
Sbjct: 2920 FYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGHPGVPPN--AVLSGEKYTFGSTV 2977
Query: 810 FYQCDENWELEGVIRRMCQENGTWSLEPPICK---EITCPDPSAQIKAGSGLLVVTSTLS 866
Y C L G R CQ NG WS P C TC DP G G S
Sbjct: 2978 HYSCTGKRSLLGQSSRTCQLNGHWSGSQPHCSGDATGTCGDPGT---PGHGSR-QESNFR 3033
Query: 867 IGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTL 926
Y C+ GY L G + RTC++ G W G P C + C +PG NGK+ +G+T
Sbjct: 3034 TKSTVRYACDTGYILHGSEERTCLANGSWTGRQPECKAVQCGNPGTTANGKVFRIDGTT- 3092
Query: 927 FGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCEL 964
F SSV Y C+ Y GP +R+C +G WSG P+C +
Sbjct: 3093 FSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNCTI 3130
Score = 280 bits (686), Expect = 2e-74
Identities = 181/637 (28%), Positives = 262/637 (41%), Gaps = 47/637 (7%)
Query: 346 CQYLPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDK--SRHCKKDGFWS--G 401
CQ + +CG P N IL DY VG+R+ Y C +G+ L + + C+ DG WS
Sbjct: 2587 CQAI--SCGIPKAPTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHN 2644
Query: 402 APPSCKYVNCGGLTP--IEDGDVALID-NRTTHGARALYSCRENFTLVGNPERTCGDEGI 458
P C V C + +E G +++ + + + ++SC + +G C G
Sbjct: 2645 KTPRCVVVTCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGT 2704
Query: 459 WD--GEAPRCLFDWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGA 516
W E P C C + P N + GS A +TC+ G +L GS C G
Sbjct: 2705 WSWRNERPYCQIISCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSGL 2764
Query: 517 WSGVPPSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKW 576
WS C +CG P + V I Y + C P + L G+ +C +D W
Sbjct: 2765 WSESETRCLAGHCGIPELIVNGQV-IGENYGYRDTVVYQCNPGFRLIGSSVRICQQDHNW 2823
Query: 577 SYDIPSCELTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSG 636
S +PSC SC P P G + + + F C G+ + G CQ + +WS
Sbjct: 2824 SGQLPSCVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSH 2883
Query: 637 DSPTCEYIDCGK--LPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQW 694
P C+ ++C +P ++ +G G+V+ Y C Y L G C QW
Sbjct: 2884 PPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQW 2943
Query: 695 SDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCE 754
P C I C P V +++S G Y G+ V Y C
Sbjct: 2944 DKPLPECIMIDCGHPGVPPNAVLS---------------------GEKYTFGSTVHYSCT 2982
Query: 755 KGYKVIGESLSTCEDNGQWSGTTPTCQ---YVDCGNPGRIENGKVTLPSNATFYGATAFY 811
++G+S TC+ NG WSG+ P C CG+PG +G + T +T Y
Sbjct: 2983 GKRSLLGQSSRTCQLNGHWSGSQPHCSGDATGTCGDPGTPGHGSRQESNFRT--KSTVRY 3040
Query: 812 QCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEA 871
CD + L G R C NG+W+ P CK + C +P +G + +
Sbjct: 3041 ACDTGYILHGSEERTCLANGSWTGRQPECKAVQCGNPGT---TANGKVFRIDGTTFSSSV 3097
Query: 872 HYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSV 931
Y C GY L G R C + G W+GT+P C I C PG NG + + G +V
Sbjct: 3098 IYSCMEGYILSGPSVRQCTANGTWSGTLPNCTIISCGDPGIPANG--LRYGDDYVVGQNV 3155
Query: 932 EYYCLSQY--QRVGPFLRKCLDDGRWSGEEPSCELAT 966
Y C Y + G +R C +G WSG P+C T
Sbjct: 3156 SYMCQPGYTMELNGSRIRTCTINGTWSGVMPTCRAVT 3192
Score = 277 bits (679), Expect = 2e-73
Identities = 181/628 (28%), Positives = 259/628 (41%), Gaps = 44/628 (7%)
Query: 349 LPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKY 408
+P +CG P + GN ++ + + C G+++ G C+ + WS PP CK
Sbjct: 2831 VPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKV 2890
Query: 409 VNCG--GLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRC 466
VNC G+ + + T+G Y C + L G+ C G WD P C
Sbjct: 2891 VNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPEC 2950
Query: 467 LFDWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCK- 525
+ C P NA ++ + GS Y+C L G +S TC L G WSG P C
Sbjct: 2951 IMIDCGHPGVPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHWSGSQPHCSG 3010
Query: 526 --YVNCGTP-TIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPS 582
CG P T GS N T S ++ C+ Y L+G+EE C +G W+ P
Sbjct: 3011 DATGTCGDPGTPGHGSRQESNFRTK--STVRYACDTGYILHGSEERTCLANGSWTGRQPE 3068
Query: 583 CELTSCPEPEVPSGGYMEAFDYYVHST-INFHCEAGHKLIGEPNLVCQQDGEWSGDSPTC 641
C+ C P + G + D S+ + + C G+ L G C +G WSG P C
Sbjct: 3069 CKAVQCGNPGTTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNC 3128
Query: 642 EYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNY--RLVGPVRRTCTEEFQWSDSSP 699
I CG P +P + + +G + Y C Y L G RTCT WS P
Sbjct: 3129 TIISCGD-PGIPANGLRYGDDYV-VGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVMP 3186
Query: 700 RCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKV 759
C + C P + S+ R G + G + Y C GY++
Sbjct: 3187 TCRAVTCPTPP---------------------QISNGRLEGTNFDWGFSISYICSPGYEL 3225
Query: 760 IGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWEL 819
++ TC NG WSG P C CG+PG GK + Y + + C+ + L
Sbjct: 3226 SFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQGK--REGKSFIYQSEVSFSCNFPFIL 3283
Query: 820 EGVIRRMCQENGTWSLEPPICKEIT---CPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCE 876
G R+CQ +GTWS P C E T C +P G T +G + C+
Sbjct: 3284 VGSSTRICQADGTWSGSSPHCIEPTQTSCENPGV---PRHGSQNNTFGFQVGSVVQFHCK 3340
Query: 877 RGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCL 936
+G+ L+G TRTC+ W+G P CIP C+ P + V+ G ++ Y C
Sbjct: 3341 KGHLLQGSTTRTCLPDLTWSGIQPECIPHSCKQPETPAHAN-VVGMDLPSHGYTLIYTCQ 3399
Query: 937 SQYQRV-GPFLRKCLDDGRWSGEEPSCE 963
+ G R C D W+G+ P CE
Sbjct: 3400 PGFFLAGGTEHRVCRSDNTWTGKVPICE 3427
Score = 240 bits (587), Expect = 2e-62
Identities = 152/524 (29%), Positives = 226/524 (43%), Gaps = 49/524 (9%)
Query: 470 WCPDPPAVSNASV-TVNGHKAGSLASYTCENGHILSGSTSVTCTLGG----AWSGVPPSC 524
+C P + + + + G + S+ + C+ G L G +S C AW P+C
Sbjct: 2528 YCSTPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPAC 2587
Query: 525 KYVNCGTPTIHKGSFVLINGTTTY--GSIAQFTCEPDYWLNGAE--ELVCNRDGKWSYD- 579
+ ++CG P +L TT Y G+ + C Y L+ E VC DG WS
Sbjct: 2588 QAISCGIPKAPTNGGIL---TTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHN 2644
Query: 580 -IPSCELTSCPEPE---VPSGGY--MEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGE 633
P C + +CP + G + + Y + + F C+ G+ +G ++ C +G
Sbjct: 2645 KTPRCVVVTCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGT 2704
Query: 634 WS--GDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEE 691
WS + P C+ I CG+LPT P G + T GS ++C + LVG R C
Sbjct: 2705 WSWRNERPYCQIISCGELPTPPNGNK--IGTQTSYGSTAIFTCDLGFMLVGSAVRECLSS 2762
Query: 692 FQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKY 751
WS+S RC C P + IV+ + +G Y V Y
Sbjct: 2763 GLWSESETRCLAGHCGIP----ELIVN-----------------GQVIGENYGYRDTVVY 2801
Query: 752 RCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFY 811
+C G+++IG S+ C+ + WSG P+C V CG+PG G+ + N + +
Sbjct: 2802 QCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGHPGSPIYGRTS--GNGFNFNDVVTF 2859
Query: 812 QCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEA 871
C+ + ++G + CQ N WS PP+CK + C DP + + + G
Sbjct: 2860 SCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVV 2919
Query: 872 HYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSV 931
Y C GY L G C GQW+ +P CI IDC PG N V+S FGS+V
Sbjct: 2920 FYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGHPGVPPNA--VLSGEKYTFGSTV 2977
Query: 932 EYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCE-LATNEAVDSGT 974
Y C + +G R C +G WSG +P C AT D GT
Sbjct: 2978 HYSCTGKRSLLGQSSRTCQLNGHWSGSQPHCSGDATGTCGDPGT 3021
Score = 151 bits (365), Expect = 2e-35
Identities = 147/571 (25%), Positives = 220/571 (38%), Gaps = 52/571 (9%)
Query: 411 CGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTC--GDEGIWDGEAPRCLF 468
C P+ + ++ D+ G Y C FTLVGN TC G+ DG P C
Sbjct: 2355 CQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQV 2414
Query: 469 DWCP-DPPAVSNASVTVN-GHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKY 526
CP + + + V ++ G+ C + ++T + +
Sbjct: 2415 -LCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVLQ 2473
Query: 527 VNCGTPTIHKGSFVLINGTTTYGSIAQFTCE-PDYWLNGAEELVCNRDG-KWSYDIPSCE 584
V G P I S VLI+ + Y S T + +L + + N+ G + Y C
Sbjct: 2474 VYDG-PNIQ--SPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAFYCS 2530
Query: 585 LTSCPEPEVPSGGY-MEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDG----EWSGDSP 639
PE P GY + ++S + + C+ G +L+G+ + VC++ W P
Sbjct: 2531 -----TPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVP 2585
Query: 640 TCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRT--CTEEFQWS-- 695
C+ I CG +P P +L +G+ + Y C YRL T C + WS
Sbjct: 2586 ACQAISCG-IPKAPTNG-GILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNH 2643
Query: 696 DSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEK 755
+ +PRC + C S+ HG I G+ Y V + C+
Sbjct: 2644 NKTPRCVVVTCP----------SINSFILEHGRWRIVN------GSHYEYKTKVVFSCDP 2687
Query: 756 GYKVIGESLSTCEDNGQWS--GTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQC 813
GY +G + C NG WS P CQ + CG NG T YG+TA + C
Sbjct: 2688 GYHGLGPASIECLPNGTWSWRNERPYCQIISCGELPTPPNGNKI--GTQTSYGSTAIFTC 2745
Query: 814 DENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHY 873
D + L G R C +G WS C C P + V+ Y
Sbjct: 2746 DLGFMLVGSAVRECLSSGLWSESETRCLAGHCGIPELIVNG----QVIGENYGYRDTVVY 2801
Query: 874 QCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEY 933
QC G+ L G R C W+G +P C+P+ C PG+ G+ NG F V +
Sbjct: 2802 QCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGHPGSPIYGR-TSGNGFN-FNDVVTF 2859
Query: 934 YCLSQYQRVGPFLRKCLDDGRWSGEEPSCEL 964
C Y GP +C + +WS P C++
Sbjct: 2860 SCNIGYLMQGPTKAQCQANRQWSHPPPMCKV 2890
Score = 126 bits (305), Expect = 3e-28
Identities = 73/241 (30%), Positives = 108/241 (44%), Gaps = 7/241 (2%)
Query: 352 TCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNC 411
TC +P ++ N + G ++D G I Y C G+ L C +G WSG P C C
Sbjct: 3192 TCPTPPQISNGRLEGTNFDWGFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQCLPKFC 3251
Query: 412 GGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDW- 470
G P + + +SC F LVG+ R C +G W G +P C+
Sbjct: 3252 GD--PGIPAQGKREGKSFIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQ 3309
Query: 471 --CPDPPAVSNASVTVN-GHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYV 527
C +P + S G + GS+ + C+ GH+L GST+ TC WSG+ P C
Sbjct: 3310 TSCENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECIPH 3369
Query: 528 NCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWL-NGAEELVCNRDGKWSYDIPSCELT 586
+C P + V+ ++G +TC+P ++L G E VC D W+ +P CE
Sbjct: 3370 SCKQPETPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPICEAG 3429
Query: 587 S 587
S
Sbjct: 3430 S 3430
Score = 57.2 bits (132), Expect = 3e-07
Identities = 28/87 (32%), Positives = 47/87 (54%), Gaps = 1/87 (1%)
Query: 571 NRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQ 630
N K Y+ + SC +P +P G D+ + ST++F C++G++L E L+C++
Sbjct: 953 NNGFKIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEK 1012
Query: 631 DGEWSGDSPTCEYIDCGKLPTLPYGTM 657
+ WS PTC+ + CG P GT+
Sbjct: 1013 NHWWSHPLPTCDAL-CGGDVRGPSGTI 1038
Score = 56.0 bits (129), Expect = 7e-07
Identities = 26/74 (35%), Positives = 39/74 (52%), Gaps = 1/74 (1%)
Query: 584 ELTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEY 643
E SC +P P G E + + F C+ G +LIGE ++VCQ++ +WS + P C +
Sbjct: 620 EKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIF 679
Query: 644 IDCGKLPTLPYGTM 657
C T P GT+
Sbjct: 680 -PCLSNFTAPMGTV 692
Score = 55.6 bits (128), Expect = 9e-07
Identities = 140/626 (22%), Positives = 221/626 (35%), Gaps = 66/626 (10%)
Query: 352 TCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNC 411
+CG P L G+ + + ++C G L+G+KS C+++ WS P C +
Sbjct: 623 SCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPCL 682
Query: 412 GGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNP-ERTCGDEGIWDGEAPRCLFDW 470
T G V D +G +C +T++ +P R +D E+ FD+
Sbjct: 683 SNFT-APMGTVLSPDYPEGYGNN--LNC--IWTIISDPGSRIHLSFNDFDLESQ---FDF 734
Query: 471 CPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVP-PSCKYVNC 529
S S + + S+ N HIL ++ G + + + C
Sbjct: 735 LAVKDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTFGHNEC 794
Query: 530 GTPTIHKGSFVLINGTTTYGSIAQFTCEPDY-WLNGAEELVC-NRDGK--WSYDIPSCEL 585
P I + GS CE + G E + C DGK WS IP C
Sbjct: 795 PDPGIPINA-RRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKCGA 853
Query: 586 TSCPEPEVPSGGYME-AFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYI 644
PSG + + Y ++N CE + EP + E + +
Sbjct: 854 PCGGHFSAPSGVILSPGWPGYYKDSLN--CE--WVIEAEPGHSIKITFERFQTELNYDVL 909
Query: 645 DCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEI 704
+ P L + NG T + + S Y L F+ S
Sbjct: 910 EVHDGPNLLSPLLGSYNG-TQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTY 968
Query: 705 RCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESL 764
C DP + + R +GH + IG+ V + C+ GY++ E
Sbjct: 969 SCLDP--------GIPVHGRRYGH-------------DFSIGSTVSFSCDSGYRLSHEEP 1007
Query: 765 STCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIR 824
CE N WS PTC + CG R +G + P FY + C W ++
Sbjct: 1008 LLCEKNHWWSHPLPTCDAL-CGGDVRGPSGTILSPGYPEFYPNS--LNC--TWTVDVTHG 1062
Query: 825 RMCQEN-GTWSLEPP-----ICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERG 878
+ Q N T+ LE I + + P A++ GS L T++ G +++ +
Sbjct: 1063 KGVQFNFHTFHLEDHHDYLLITENGSFTQPLARL-TGSDL---PPTINAGLYGNFRAQLR 1118
Query: 879 YNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQ 938
+ + IS +N T C PG + G + N G ++ + C S
Sbjct: 1119 F-----ISDFSISYEGFNITFSEYNLEPCEDPGIPQYGSRIGFNFG--IGDTLTFSCSSG 1171
Query: 939 YQRVGPFLRKCLDDGR--WSGEEPSC 962
Y+ G CL GR WS P C
Sbjct: 1172 YRLEGTSEIICLGGGRRVWSAPLPRC 1197
Score = 50.8 bits (116), Expect = 3e-05
Identities = 59/248 (23%), Positives = 99/248 (39%), Gaps = 22/248 (8%)
Query: 349 LPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHC--KKDG--FWSGAPP 404
L +C P ++N T LG DY +GS + Y C G++L G + C DG W+ A P
Sbjct: 1657 LRESCFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALP 1716
Query: 405 SCKYVNCGGLTPIEDGDVALIDNRTTHGARALYSCREN--FTLVGNPERTCGDEGIWDGE 462
SC + CG + +G V L N + YS N +++ E + ++
Sbjct: 1717 SC-HAPCGSRSTGSEGTV-LSPNYPKN-----YSVGHNCVYSIAVPKEFVVFGQFVFFQT 1769
Query: 463 APRCLFDWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGG---AWSG 519
+ + + P S+ +++G +G + N + ++ T G +
Sbjct: 1770 SLHDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVYQA 1829
Query: 520 VPPSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVC----NRDGK 575
VP + P G I GS F C P Y L+G+ + C N +
Sbjct: 1830 VPRTSSTQCSSVPEPRFGR--RIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQ 1887
Query: 576 WSYDIPSC 583
W+ +P+C
Sbjct: 1888 WNDSLPTC 1895
Score = 48.4 bits (110), Expect = 1e-04
Identities = 24/73 (32%), Positives = 34/73 (46%), Gaps = 4/73 (5%)
Query: 588 CPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGE----WSGDSPTCEY 643
CP+P P G D+ + ST+ F C+ + L G ++ CQ+ E WS P C+
Sbjct: 446 CPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKV 505
Query: 644 IDCGKLPTLPYGT 656
CG P GT
Sbjct: 506 KTCGSNLQGPSGT 518
Score = 48.4 bits (110), Expect = 1e-04
Identities = 27/76 (35%), Positives = 37/76 (48%), Gaps = 3/76 (3%)
Query: 584 ELTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQ--DGEWSGDSPTC 641
+L SCP+P G++ D+ V TI+F C G+ LIG L C W+ P C
Sbjct: 2180 QLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRC 2239
Query: 642 EYIDCGKLPTLPYGTM 657
E + CG T GT+
Sbjct: 2240 EAL-CGGNITAMNGTI 2254
Score = 48.0 bits (109), Expect = 2e-04
Identities = 28/88 (31%), Positives = 39/88 (44%), Gaps = 5/88 (5%)
Query: 471 CPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTC----TLGGAWSGVPPSCKY 526
CPDP N + GS ++C+ ++L G+ S+TC + AWS P CK
Sbjct: 446 CPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKV 505
Query: 527 VNCGTPTI-HKGSFVLINGTTTYGSIAQ 553
CG+ G+F N Y S AQ
Sbjct: 506 KTCGSNLQGPSGTFTSPNFPFQYDSNAQ 533
Score = 47.6 bits (108), Expect = 2e-04
Identities = 23/57 (40%), Positives = 26/57 (45%), Gaps = 3/57 (5%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
CGHP VPPNA +S E G+ Y C L G R C L G W+ P C
Sbjct: 2955 CGHPGVPPNAVLS---GEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHWSGSQPHC 3008
Score = 46.0 bits (104), Expect = 7e-04
Identities = 22/65 (33%), Positives = 30/65 (46%), Gaps = 3/65 (4%)
Query: 585 LTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQD--GEWSGDSPTCE 642
L SCPEP+ PS G Y V ++F C+ G+ L G ++ C W+ P C
Sbjct: 2009 LDSCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPIC- 2067
Query: 643 YIDCG 647
CG
Sbjct: 2068 LAQCG 2072
Score = 45.6 bits (103), Expect = 0.001
Identities = 107/466 (22%), Positives = 166/466 (35%), Gaps = 57/466 (12%)
Query: 471 CPDPPAVSNASVTVNGHKAGSLASYTCENGHI-LSGSTSVTCTLGGA---WSGVPPSCKY 526
CPDP NA + + GS S CE G I G+ ++TC L WSG+ P C
Sbjct: 794 CPDPGIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKCG- 852
Query: 527 VNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAE-----ELVCNR-DGKWSYDI 580
CG +L G Y CE W+ AE ++ R + +YD+
Sbjct: 853 APCGGHFSAPSGVILSPGWPGYYK-DSLNCE---WVIEAEPGHSIKITFERFQTELNYDV 908
Query: 581 PSCELTSCPEPEVP-SGGYM-EAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDS 638
E+ P P G Y ++ S+ NF + L N + +S
Sbjct: 909 --LEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFI----YLLFTTDNSRSNNGFKIHYES 962
Query: 639 PTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSS 698
T C P +P + + +GS + +SC + YRL C + WS
Sbjct: 963 VTVNTYSCLD-PGIPVHGRRYGHDFS-IGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPL 1020
Query: 699 PRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYK 758
P C+ + C + + G + ++L + DV + G V++ +
Sbjct: 1021 PTCDAL-CGGDVRGPSGTILSPGYPEFYPNSL-NCTWTVDVTH----GKGVQFNFHTFHL 1074
Query: 759 VIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWE 818
+NG S T P + P I G L N + A + D +
Sbjct: 1075 EDHHDYLLITENG--SFTQPLARLTGSDLPPTINAG---LYGN---FRAQLRFISDFSIS 1126
Query: 819 LEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERG 878
EG + N LEP C DP + GS + IG + C G
Sbjct: 1127 YEGFNITFSEYN----LEP-------CEDPGIP-QYGSR---IGFNFGIGDTLTFSCSSG 1171
Query: 879 YNLKGHQTRTCISKGQ--WNGTVPVCIPIDCRSPGNIENGKIVISN 922
Y L+G C+ G+ W+ +P C+ +C + G ++ N
Sbjct: 1172 YRLEGTSEIICLGGGRRVWSAPLPRCV-AECGASATNNEGILLSPN 1216
Score = 44.8 bits (101), Expect = 0.002
Identities = 21/58 (36%), Positives = 27/58 (46%), Gaps = 1/58 (1%)
Query: 2 CGHPAVPPNA-RVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C P +P N+ R S N GT+ Y+C+ GY LFG+ C G W P C
Sbjct: 2893 CSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPEC 2950
Score = 44.4 bits (100), Expect = 0.002
Identities = 54/230 (23%), Positives = 82/230 (35%), Gaps = 15/230 (6%)
Query: 739 VGNTYRIGALVKYRCEKGYKVIGESLSTCED--NGQWSGTTPTCQYVDCGNPGRIENGKV 796
+GN + +G + + C GY +IG S TC + W+ P C+ + CG NG +
Sbjct: 2196 IGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEAL-CGGNITAMNGTI 2254
Query: 797 TLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGS 856
P Y F C W + N T PI IT D Q
Sbjct: 2255 YSPGYPDEY--PNFQDC--FWLVRVPPGNGIYINFTVLQTEPIYDFITVWDGPDQNSPQI 2310
Query: 857 GLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENG 916
G + L E+ Y +K H T + G + + C+ P + N
Sbjct: 2311 GQFSGNTAL----ESVYSTSNQILIKFHSDFT--TSGFFVLSYHAYQLRVCQPPPPVPNA 2364
Query: 917 KIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGR--WSGEEPSCEL 964
+I+ + G + Y CL + VG + C R G P C++
Sbjct: 2365 EILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQV 2414
Score = 43.6 bits (98), Expect = 0.004
Identities = 26/93 (27%), Positives = 43/93 (46%), Gaps = 4/93 (4%)
Query: 333 NDVGCNLDYLHWICQ-YLPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSR 391
+D N H + Q Y +C P N ++GND+ VG I ++C G+ L+G+ +
Sbjct: 2163 SDYSQNKQGFHIVYQAYQLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSAL 2222
Query: 392 HCKK--DGFWSGAPPSCKYVNCGGLTPIEDGDV 422
C W+ P C+ + CGG +G +
Sbjct: 2223 TCLHGVSRNWNHPLPRCEAL-CGGNITAMNGTI 2254
Score = 43.2 bits (97), Expect = 0.005
Identities = 22/64 (34%), Positives = 34/64 (53%), Gaps = 4/64 (6%)
Query: 353 CGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKK--DGF--WSGAPPSCKY 408
C P + N +G+D+ +GS + + C E ++L G KS C++ + F WS P CK
Sbjct: 446 CPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKV 505
Query: 409 VNCG 412
CG
Sbjct: 506 KTCG 509
Score = 42.3 bits (95), Expect = 0.009
Identities = 33/124 (26%), Positives = 61/124 (49%), Gaps = 10/124 (8%)
Query: 726 HGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDC 785
H + RT + V T+R+ + ++ +G+K+ ++ + + G T + C
Sbjct: 391 HAEQIERTKELAVV--THRVKKAIDFK-SRGFKLFPGKDNSNKFSILNEGGIKTASNL-C 446
Query: 786 GNPGRIENGKVTLPSNATFYGATAFYQCDENWELEG----VIRRMCQENGTWSLEPPICK 841
+PG ENGK + S+ + G+T + CDE++ L+G +R+ + WS P+CK
Sbjct: 447 PDPGEPENGK-RIGSDFSL-GSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCK 504
Query: 842 EITC 845
TC
Sbjct: 505 VKTC 508
Score = 42.3 bits (95), Expect = 0.009
Identities = 19/62 (30%), Positives = 35/62 (56%), Gaps = 6/62 (9%)
Query: 844 TCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCI--SKGQWNGTVPV 901
+CP+P SG+ + + +G +QC++GY+L+GH TC+ +WN +P+
Sbjct: 2011 SCPEPQTP---SSGIKIGDRYM-VGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPI 2066
Query: 902 CI 903
C+
Sbjct: 2067 CL 2068
Score = 42.3 bits (95), Expect = 0.009
Identities = 20/57 (35%), Positives = 24/57 (42%), Gaps = 3/57 (5%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
CG P P + E N + Y CD GY L G+ +R C G WT P C
Sbjct: 3016 CGDPGTPGHGS---RQESNFRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQPEC 3069
Score = 41.9 bits (94), Expect = 0.012
Identities = 22/59 (37%), Positives = 29/59 (49%), Gaps = 5/59 (8%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGY--ELFGARQRECTLRGDWTLEPPFC 58
CG P +P N + ++ V G Y C GY EL G+R R CT+ G W+ P C
Sbjct: 3133 CGDPGIPANG---LRYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVMPTC 3188
Score = 41.1 bits (92), Expect = 0.021
Identities = 49/223 (21%), Positives = 81/223 (36%), Gaps = 15/223 (6%)
Query: 432 GARALYSCRENFTLVGNPERTC--GDEGIWDGEAPRCLFDWCPDPPAVSNASVTVN-GHK 488
G +SC + L G E C G +W PRC+ + C A +N + ++ +
Sbjct: 1161 GDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVAE-C-GASATNNEGILLSPNYP 1218
Query: 489 AGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTIHK-GSFVLINGTTT 547
++ C + + + K + T H G+F G +
Sbjct: 1219 LNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDGKDKTTHLLGAFT---GASM 1275
Query: 548 YGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGY-MEAFDYYV 606
G T WL + +G + S EL+ C +P +P GY + ++
Sbjct: 1276 RGLTLSSTSN-QLWLEFNSDTEGTDEG-FQLVYTSFELSHCEDPGIPQFGYKISDQGHFA 1333
Query: 607 HSTINFHCEAGHKLIGEPNLVCQ--QDGEWSGDSPTCEYIDCG 647
STI + C G+ L G L C + W P+C +CG
Sbjct: 1334 GSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSC-IAECG 1375
Score = 41.1 bits (92), Expect = 0.021
Identities = 25/75 (33%), Positives = 36/75 (48%), Gaps = 5/75 (6%)
Query: 587 SCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVC--QQDGE--WSGDSPTCE 642
SC +P G DY + ST+ ++C+AG+ L G L C DG W+ P+C
Sbjct: 1660 SCFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSC- 1718
Query: 643 YIDCGKLPTLPYGTM 657
+ CG T GT+
Sbjct: 1719 HAPCGSRSTGSEGTV 1733
Score = 41.1 bits (92), Expect = 0.021
Identities = 22/66 (33%), Positives = 35/66 (53%), Gaps = 5/66 (7%)
Query: 739 VGNTYRIGALVKYRCEKGYKVIGESLSTC--EDNGQ--WSGTTPTCQYVDCGNPGRIENG 794
+G Y++G+ V Y C+ GY + G S TC D+G+ W+ P+C + CG+ G
Sbjct: 1673 LGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSC-HAPCGSRSTGSEG 1731
Query: 795 KVTLPS 800
V P+
Sbjct: 1732 TVLSPN 1737
Score = 41.1 bits (92), Expect = 0.021
Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 9/77 (11%)
Query: 471 CPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGA--WSGVPPSCKYVN 528
CPDP N V N G S+ C G+ L G++++TC G + W+ P C+ +
Sbjct: 2184 CPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEAL- 2242
Query: 529 CGTPTIHKGSFVLINGT 545
CG G+ +NGT
Sbjct: 2243 CG------GNITAMNGT 2253
Score = 41.1 bits (92), Expect = 0.021
Identities = 23/77 (29%), Positives = 35/77 (45%), Gaps = 3/77 (3%)
Query: 1 RCGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGT 60
+CG+P N +V + + +Y C EGY L G R+CT G W+ P C T
Sbjct: 3073 QCGNPGTTANGKVF--RIDGTTFSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNC-T 3129
Query: 61 NVAFRKPANQSTTVRGG 77
++ P + +R G
Sbjct: 3130 IISCGDPGIPANGLRYG 3146
Score = 39.9 bits (89), Expect = 0.049
Identities = 21/62 (33%), Positives = 32/62 (51%), Gaps = 5/62 (8%)
Query: 542 INGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGK----WSYDIPSCELTSC-PEPEVPSG 596
I + GS QF+C+ DY L GA+ + C R + WS P C++ +C + PSG
Sbjct: 458 IGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSG 517
Query: 597 GY 598
+
Sbjct: 518 TF 519
Score = 39.1 bits (87), Expect = 0.085
Identities = 21/83 (25%), Positives = 41/83 (49%), Gaps = 6/83 (7%)
Query: 735 DNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQ----WSGTTPTCQYVDCGNPGR 790
+ + +G+ + +G+ V++ C++ Y + G TC+ + WS P C+ CG+ +
Sbjct: 454 NGKRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQ 513
Query: 791 IENGKVTLPSNATFYGATAFYQC 813
+G T P+ Y + A QC
Sbjct: 514 GPSGTFTSPNFPFQYDSNA--QC 534
Score = 39.1 bits (87), Expect = 0.085
Identities = 48/229 (20%), Positives = 78/229 (34%), Gaps = 16/229 (6%)
Query: 739 VGNTYRIGALVKYRCEKGYKVIGESLSTCEDN--GQWSGTTPTCQYVDCGNPGRIENGKV 796
+G+ Y +G +V ++C++GY + G S TC +W+ P C CG +G +
Sbjct: 2024 IGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPIC-LAQCGGAMSDFSGVI 2082
Query: 797 TLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGS 856
P Y ++ N + + T ++ + + S I S
Sbjct: 2083 LSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLS 2142
Query: 857 GLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENG 916
G + +S S E Y+ Q C P NG
Sbjct: 2143 GPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQ---------SCPDPRPFRNG 2193
Query: 917 KIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLD--DGRWSGEEPSCE 963
VI N T+ G ++ + C Y +G CL W+ P CE
Sbjct: 2194 -FVIGNDFTV-GQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCE 2240
Score = 38.7 bits (86), Expect = 0.11
Identities = 19/64 (29%), Positives = 30/64 (46%), Gaps = 3/64 (4%)
Query: 469 DWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGA--WSGVPPSCKY 526
D CP+P S+ + + G + S+ C+ G+ L G + +TC G W+ P C
Sbjct: 2010 DSCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPIC-L 2068
Query: 527 VNCG 530
CG
Sbjct: 2069 AQCG 2072
Score = 37.9 bits (84), Expect = 0.20
Identities = 24/88 (27%), Positives = 43/88 (48%), Gaps = 9/88 (10%)
Query: 343 HWICQYLPPT----CGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCK---- 394
H++ Q +P T C S + +GN++ VGS +++ C G++L G + C+
Sbjct: 1824 HFVYQAVPRTSSTQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPN 1883
Query: 395 KDGFWSGAPPSCKYVNCGGLTPIEDGDV 422
W+ + P+C V CGG+ G +
Sbjct: 1884 SLAQWNDSLPTC-IVPCGGILTKRKGTI 1910
Score = 37.9 bits (84), Expect = 0.20
Identities = 21/67 (31%), Positives = 30/67 (44%), Gaps = 5/67 (7%)
Query: 737 RDVGNTYRIGALVKYRCEKGYKVIGESLSTCE----DNGQWSGTTPTCQYVDCGNPGRIE 792
R +GN + +G+ V + C GY + G CE QW+ + PTC V CG
Sbjct: 1848 RRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTC-IVPCGGILTKR 1906
Query: 793 NGKVTLP 799
G + P
Sbjct: 1907 KGTILSP 1913
Score = 37.9 bits (84), Expect = 0.20
Identities = 23/82 (28%), Positives = 33/82 (40%), Gaps = 4/82 (4%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTN 61
CGHP P R S N N + + C+ GY + G + +C W+ PP C
Sbjct: 2835 CGHPGSPIYGRTS-GNGFNF--NDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKV- 2890
Query: 62 VAFRKPANQSTTVRGGAAANGN 83
V P + + R +GN
Sbjct: 2891 VNCSDPGIPANSKRESKIEHGN 2912
Score = 37.5 bits (83), Expect = 0.26
Identities = 19/51 (37%), Positives = 26/51 (50%), Gaps = 5/51 (9%)
Query: 867 IGGEAHYQCERGYNLKGHQTRTCI----SKGQWNGTVPVC-IPIDCRSPGN 912
+G Y C+ GY L+G+ T TCI + WN +P C P RS G+
Sbjct: 1679 LGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCGSRSTGS 1729
Score = 36.7 bits (81), Expect = 0.45
Identities = 26/85 (30%), Positives = 37/85 (43%), Gaps = 9/85 (10%)
Query: 844 TCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISK----GQWNGTV 899
+C +P K G+L T +G + Y C GY L GH TCI+ W+ V
Sbjct: 137 SCGNPGVPPK---GVLYGTR-FDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPV 192
Query: 900 PVCIPIDCRSPGNIENGKIVISNGS 924
P+C D G + +IS+ S
Sbjct: 193 PICRAEDA-CGGTMRGSSGIISSPS 216
Score = 36.7 bits (81), Expect = 0.45
Identities = 19/57 (33%), Positives = 27/57 (47%), Gaps = 3/57 (5%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
CG PPN I + + G+ A++ CD G+ L G+ REC G W+ C
Sbjct: 2719 CGELPTPPNGN-KIGTQTSY--GSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRC 2772
Score = 36.3 bits (80), Expect = 0.60
Identities = 20/65 (30%), Positives = 27/65 (41%), Gaps = 4/65 (6%)
Query: 586 TSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGE---WSGDSPTCE 642
T+C +P VP G T+ F C+ G++L GE + C Q W P C
Sbjct: 1486 TACRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVC- 1544
Query: 643 YIDCG 647
CG
Sbjct: 1545 IAPCG 1549
Score = 36.3 bits (80), Expect = 0.60
Identities = 24/60 (40%), Positives = 30/60 (50%), Gaps = 6/60 (10%)
Query: 907 CRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCL--DDGR--WSGEEPSC 962
C PGNI NG + + GS+V YYC + Y G C+ DDGR W+ PSC
Sbjct: 1661 CFDPGNIMNGTRLGMDYK--LGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSC 1718
Score = 35.5 bits (78), Expect = 1.0
Identities = 20/67 (29%), Positives = 30/67 (44%), Gaps = 5/67 (7%)
Query: 352 TCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGF----WSGAPPSCK 407
+CG+P + G +DVG +I Y C G++L G C + W P C+
Sbjct: 137 SCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICR 196
Query: 408 YVN-CGG 413
+ CGG
Sbjct: 197 AEDACGG 203
Score = 35.5 bits (78), Expect = 1.0
Identities = 20/66 (30%), Positives = 29/66 (43%), Gaps = 5/66 (7%)
Query: 740 GNTYRIGALVKYRCEKGYKVIGESLSTCEDN----GQWSGTTPTCQYVD-CGNPGRIENG 794
G + +G ++Y C GY + G TC N W P C+ D CG R +G
Sbjct: 151 GTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDACGGTMRGSSG 210
Query: 795 KVTLPS 800
++ PS
Sbjct: 211 IISSPS 216
Score = 35.5 bits (78), Expect = 1.0
Identities = 22/82 (26%), Positives = 35/82 (42%), Gaps = 5/82 (6%)
Query: 580 IPSCELTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQ----QDGEWS 635
+P T C P G ++ V S++ F C G+ L G + C+ +W+
Sbjct: 1830 VPRTSSTQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWN 1889
Query: 636 GDSPTCEYIDCGKLPTLPYGTM 657
PTC + CG + T GT+
Sbjct: 1890 DSLPTC-IVPCGGILTKRKGTI 1910
Score = 35.1 bits (77), Expect = 1.4
Identities = 21/67 (31%), Positives = 26/67 (38%), Gaps = 5/67 (7%)
Query: 586 TSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVC----QQDGEWSGDSPTC 641
+SC P VP G + + V I + C G+ L G P L C W P C
Sbjct: 136 SSCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPIC 195
Query: 642 EYID-CG 647
D CG
Sbjct: 196 RAEDACG 202
Score = 35.1 bits (77), Expect = 1.4
Identities = 21/60 (35%), Positives = 25/60 (41%), Gaps = 6/60 (10%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTL---RGDWTLEPPFC 58
C P VP N N + G V++CD GYEL G + C R W PP C
Sbjct: 1488 CRDPGVPMNGT---RNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVC 1544
Score = 35.1 bits (77), Expect = 1.4
Identities = 20/59 (33%), Positives = 27/59 (45%), Gaps = 5/59 (8%)
Query: 785 CGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMC---QENGTWSLEPPIC 840
C +PG NG T + G T +QCD +EL+G R C + W PP+C
Sbjct: 1488 CRDPGVPMNG--TRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVC 1544
Score = 34.7 bits (76), Expect = 1.8
Identities = 20/74 (27%), Positives = 28/74 (37%), Gaps = 4/74 (5%)
Query: 471 CPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTL---GGAWSGVPPSCKYV 527
C DP N + +G + G + C+ G+ L G +TC W PP C
Sbjct: 1488 CRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVC-IA 1546
Query: 528 NCGTPTIHKGSFVL 541
CG F+L
Sbjct: 1547 PCGGNLTGSSGFIL 1560
Score = 34.7 bits (76), Expect = 1.8
Identities = 19/59 (32%), Positives = 25/59 (42%), Gaps = 3/59 (5%)
Query: 528 NCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVC--NRDGKWSYDIPSCE 584
+C P + FV+ N T G F C P Y L G L C W++ +P CE
Sbjct: 2183 SCPDPRPFRNGFVIGNDFTV-GQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCE 2240
Score = 33.9 bits (74), Expect = 3.2
Identities = 19/45 (42%), Positives = 23/45 (51%), Gaps = 4/45 (8%)
Query: 666 LGSVIQYSCTTNYRLVGPVRRTC---TEEF-QWSDSSPRCEEIRC 706
LGS +Q+SC +Y L G TC E F WSD P C+ C
Sbjct: 464 LGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTC 508
Score = 33.5 bits (73), Expect = 4.2
Identities = 24/83 (28%), Positives = 35/83 (42%), Gaps = 4/83 (4%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTN 61
CG P + N +V EN VY+C+ G+ L G+ R C +W+ + P C
Sbjct: 2777 CGIPELIVNGQVI---GENYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSC-VP 2832
Query: 62 VAFRKPANQSTTVRGGAAANGND 84
V+ P + G N ND
Sbjct: 2833 VSCGHPGSPIYGRTSGNGFNFND 2855
Score = 33.1 bits (72), Expect = 5.6
Identities = 15/39 (38%), Positives = 22/39 (56%), Gaps = 3/39 (7%)
Query: 868 GGEAHYQCERGYNLKGHQTRTCI---SKGQWNGTVPVCI 903
G +QC+ GY L+G + TCI ++ W + PVCI
Sbjct: 1507 GDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCI 1545
Score = 33.1 bits (72), Expect = 5.6
Identities = 20/59 (33%), Positives = 26/59 (44%), Gaps = 4/59 (6%)
Query: 410 NCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTC--GDEGIWDGEAPRC 466
+C P +G V I N T G + C +TL+GN TC G W+ PRC
Sbjct: 2183 SCPDPRPFRNGFV--IGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRC 2239
>AB114604-1|BAC82443.1| 3707|Homo sapiens CSMD3 protein isoform 1
protein.
Length = 3707
Score = 335 bits (823), Expect = 6e-91
Identities = 195/625 (31%), Positives = 272/625 (43%), Gaps = 42/625 (6%)
Query: 346 CQYLPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPS 405
CQ + +CG N +G GS ++ C G ML+G R C G WS +
Sbjct: 2754 CQII--SCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSESETR 2811
Query: 406 CKYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPR 465
C +CG I +G V I + +Y C F L+G+ R C + W G+ P
Sbjct: 2812 CLAGHCGIPELIVNGQV--IGENYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPS 2869
Query: 466 CLFDWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCK 525
C+ C P + + NG + +++C G+++ G T C WS PP CK
Sbjct: 2870 CVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCK 2929
Query: 526 YVNC---GTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPS 582
VNC G P K + +G TYG++ + C P Y+L G+ L+C +G+W +P
Sbjct: 2930 VVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPE 2989
Query: 583 CELTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCE 642
C + C P VP + Y ST+++ C L+G+ + CQ +G WSG P C
Sbjct: 2990 CIMIDCGHPGVPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHWSGSQPHCS 3049
Query: 643 ---YIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSP 699
CG T +G+ + N T S ++Y+C T Y L G RTC W+ P
Sbjct: 3050 GDATGTCGDPGTPGHGSRQESNFRTK--STVRYACDTGYILHGSEERTCLANGSWTGRQP 3107
Query: 700 RCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKV 759
C+ ++C +P T N + R G T+ + V Y C +GY +
Sbjct: 3108 ECKAVQCGNP--------GTTANGKVF----------RIDGTTF--SSSVIYSCMEGYIL 3147
Query: 760 IGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENW-- 817
G S+ C NG WSGT P C + CG+PG NG + G Y C +
Sbjct: 3148 SGPSVRQCTANGTWSGTLPNCTIISCGDPGIPANG--LRYGDDYVVGQNVSYMCQPGYTM 3205
Query: 818 ELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCER 877
EL G R C NGTWS P C+ +TCP P QI G + + G Y C
Sbjct: 3206 ELNGSRIRTCTINGTWSGVMPTCRAVTCPTP-PQISNGR---LEGTNFDWGFSISYICSP 3261
Query: 878 GYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLS 937
GY L TC+ G W+G VP C+P C PG GK S ++ S V + C
Sbjct: 3262 GYELSFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQGK--REGKSFIYQSEVSFSCNF 3319
Query: 938 QYQRVGPFLRKCLDDGRWSGEEPSC 962
+ VG R C DG WSG P C
Sbjct: 3320 PFILVGSSTRICQADGTWSGSSPHC 3344
Score = 333 bits (819), Expect = 2e-90
Identities = 195/606 (32%), Positives = 280/606 (46%), Gaps = 40/606 (6%)
Query: 366 GNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWS--GAPPSCKYVNCGGLTPIEDGDVA 423
G+ Y+ +++V+ C G+ LG S C +G WS P C+ ++CG L +G+
Sbjct: 2712 GSHYEYKTKVVFSCDPGYHGLGPASIECLPNGTWSWRNERPYCQIISCGELPTPPNGNK- 2770
Query: 424 LIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVT 483
I +T++G+ A+++C F LVG+ R C G+W RCL C P + N V
Sbjct: 2771 -IGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRCLAGHCGIPELIVNGQVI 2829
Query: 484 VNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTIHKGSFVLIN 543
+ Y C G L GS+ C WSG PSC V+CG P N
Sbjct: 2830 GENYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGHPGSPIYGRTSGN 2889
Query: 544 GTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEA-- 601
G + + F+C Y + G + C + +WS+ P C++ +C +P +P+ E+
Sbjct: 2890 GFN-FNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGIPANSKRESKI 2948
Query: 602 -FDYYVHSTINFH-CEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMEL 659
+ + T+ F+ C G+ L G L+CQ +G+W P C IDCG P +P +
Sbjct: 2949 EHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGH-PGVPPNAV-- 3005
Query: 660 LNGTTH-LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVS 718
L+G + GS + YSCT L+G RTC WS S P C
Sbjct: 3006 LSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHWSGSQPHCSG-----------DATG 3054
Query: 719 VTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTP 778
G+ + GH +R N +R + V+Y C+ GY + G TC NG W+G P
Sbjct: 3055 TCGDPGTPGH------GSRQESN-FRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQP 3107
Query: 779 TCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPP 838
C+ V CGNPG NGKV TF ++ Y C E + L G R C NGTWS P
Sbjct: 3108 ECKAVQCGNPGTTANGKVFRIDGTTF-SSSVIYSCMEGYILSGPSVRQCTANGTWSGTLP 3166
Query: 839 ICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGY--NLKGHQTRTCISKGQWN 896
C I+C DP I A L +G Y C+ GY L G + RTC G W+
Sbjct: 3167 NCTIISCGDPG--IPANG--LRYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTINGTWS 3222
Query: 897 GTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWS 956
G +P C + C +P I NG++ +N +G S+ Y C Y+ P + C+ +G WS
Sbjct: 3223 GVMPTCRAVTCPTPPQISNGRLEGTNFD--WGFSISYICSPGYELSFPAVLTCVGNGTWS 3280
Query: 957 GEEPSC 962
GE P C
Sbjct: 3281 GEVPQC 3286
Score = 307 bits (754), Expect = 1e-82
Identities = 195/638 (30%), Positives = 279/638 (43%), Gaps = 50/638 (7%)
Query: 347 QYLPPTCGSPDKLLNTTILGNDY-DVGSRIVYKCPEGHMLLGDKSRHCKKDGF----WSG 401
+Y+ C +P+ + I+ + S + + C G L+G S C+K + W
Sbjct: 2563 RYIAFYCSTPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDA 2622
Query: 402 APPSCKYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERT--CGDEGIW 459
P+C+ ++CG +G + D G R Y C + + L T C +G W
Sbjct: 2623 PVPACQAISCGIPKAPTNGGILTTDYLV--GTRVTYFCNDGYRLSSKELTTAVCQSDGTW 2680
Query: 460 D--GEAPRCLFDWCPDPPAV---SNASVTVNG--HKAGSLASYTCENGHILSGSTSVTCT 512
+ PRC+ CP + VNG ++ + ++C+ G+ G S+ C
Sbjct: 2681 SNHNKTPRCVVVTCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECL 2740
Query: 513 LGGAWS--GVPPSCKYVNCG-TPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELV 569
G WS P C+ ++CG PT G+ I T+YGS A FTC+ + L G+
Sbjct: 2741 PNGTWSWRNERPYCQIISCGELPTPPNGN--KIGTQTSYGSTAIFTCDLGFMLVGSAVRE 2798
Query: 570 CNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQ 629
C G WS C C PE+ G + +Y T+ + C G +LIG +CQ
Sbjct: 2799 CLSSGLWSESETRCLAGHCGIPELIVNGQVIGENYGYRDTVVYQCNPGFRLIGSSVRICQ 2858
Query: 630 QDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCT 689
QD WSG P+C + CG + YG NG + V+ +SC Y + GP + C
Sbjct: 2859 QDHNWSGQLPSCVPVSCGHPGSPIYGRTS-GNG-FNFNDVVTFSCNIGYLMQGPTKAQCQ 2916
Query: 690 EEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALV 749
QWS P C+ + CSDP + S + + GN + G +V
Sbjct: 2917 ANRQWSHPPPMCKVVNCSDPGIPANS----------------KRESKIEHGN-FTYGTVV 2959
Query: 750 KYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATA 809
Y C GY + G S+ C+ NGQW P C +DCG+PG N L +G+T
Sbjct: 2960 FYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGHPGVPPN--AVLSGEKYTFGSTV 3017
Query: 810 FYQCDENWELEGVIRRMCQENGTWSLEPPICK---EITCPDPSAQIKAGSGLLVVTSTLS 866
Y C L G R CQ NG WS P C TC DP G G S
Sbjct: 3018 HYSCTGKRSLLGQSSRTCQLNGHWSGSQPHCSGDATGTCGDPGT---PGHGSR-QESNFR 3073
Query: 867 IGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTL 926
Y C+ GY L G + RTC++ G W G P C + C +PG NGK+ +G+T
Sbjct: 3074 TKSTVRYACDTGYILHGSEERTCLANGSWTGRQPECKAVQCGNPGTTANGKVFRIDGTT- 3132
Query: 927 FGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCEL 964
F SSV Y C+ Y GP +R+C +G WSG P+C +
Sbjct: 3133 FSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNCTI 3170
Score = 280 bits (686), Expect = 2e-74
Identities = 181/637 (28%), Positives = 262/637 (41%), Gaps = 47/637 (7%)
Query: 346 CQYLPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDK--SRHCKKDGFWS--G 401
CQ + +CG P N IL DY VG+R+ Y C +G+ L + + C+ DG WS
Sbjct: 2627 CQAI--SCGIPKAPTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHN 2684
Query: 402 APPSCKYVNCGGLTP--IEDGDVALID-NRTTHGARALYSCRENFTLVGNPERTCGDEGI 458
P C V C + +E G +++ + + + ++SC + +G C G
Sbjct: 2685 KTPRCVVVTCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGT 2744
Query: 459 WD--GEAPRCLFDWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGA 516
W E P C C + P N + GS A +TC+ G +L GS C G
Sbjct: 2745 WSWRNERPYCQIISCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSGL 2804
Query: 517 WSGVPPSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKW 576
WS C +CG P + V I Y + C P + L G+ +C +D W
Sbjct: 2805 WSESETRCLAGHCGIPELIVNGQV-IGENYGYRDTVVYQCNPGFRLIGSSVRICQQDHNW 2863
Query: 577 SYDIPSCELTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSG 636
S +PSC SC P P G + + + F C G+ + G CQ + +WS
Sbjct: 2864 SGQLPSCVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSH 2923
Query: 637 DSPTCEYIDCGK--LPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQW 694
P C+ ++C +P ++ +G G+V+ Y C Y L G C QW
Sbjct: 2924 PPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQW 2983
Query: 695 SDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCE 754
P C I C P V +++S G Y G+ V Y C
Sbjct: 2984 DKPLPECIMIDCGHPGVPPNAVLS---------------------GEKYTFGSTVHYSCT 3022
Query: 755 KGYKVIGESLSTCEDNGQWSGTTPTCQ---YVDCGNPGRIENGKVTLPSNATFYGATAFY 811
++G+S TC+ NG WSG+ P C CG+PG +G + T +T Y
Sbjct: 3023 GKRSLLGQSSRTCQLNGHWSGSQPHCSGDATGTCGDPGTPGHGSRQESNFRT--KSTVRY 3080
Query: 812 QCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEA 871
CD + L G R C NG+W+ P CK + C +P +G + +
Sbjct: 3081 ACDTGYILHGSEERTCLANGSWTGRQPECKAVQCGNPGT---TANGKVFRIDGTTFSSSV 3137
Query: 872 HYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSV 931
Y C GY L G R C + G W+GT+P C I C PG NG + + G +V
Sbjct: 3138 IYSCMEGYILSGPSVRQCTANGTWSGTLPNCTIISCGDPGIPANG--LRYGDDYVVGQNV 3195
Query: 932 EYYCLSQY--QRVGPFLRKCLDDGRWSGEEPSCELAT 966
Y C Y + G +R C +G WSG P+C T
Sbjct: 3196 SYMCQPGYTMELNGSRIRTCTINGTWSGVMPTCRAVT 3232
Score = 277 bits (679), Expect = 2e-73
Identities = 181/628 (28%), Positives = 259/628 (41%), Gaps = 44/628 (7%)
Query: 349 LPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKY 408
+P +CG P + GN ++ + + C G+++ G C+ + WS PP CK
Sbjct: 2871 VPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKV 2930
Query: 409 VNCG--GLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRC 466
VNC G+ + + T+G Y C + L G+ C G WD P C
Sbjct: 2931 VNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPEC 2990
Query: 467 LFDWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCK- 525
+ C P NA ++ + GS Y+C L G +S TC L G WSG P C
Sbjct: 2991 IMIDCGHPGVPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHWSGSQPHCSG 3050
Query: 526 --YVNCGTP-TIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPS 582
CG P T GS N T S ++ C+ Y L+G+EE C +G W+ P
Sbjct: 3051 DATGTCGDPGTPGHGSRQESNFRTK--STVRYACDTGYILHGSEERTCLANGSWTGRQPE 3108
Query: 583 CELTSCPEPEVPSGGYMEAFDYYVHST-INFHCEAGHKLIGEPNLVCQQDGEWSGDSPTC 641
C+ C P + G + D S+ + + C G+ L G C +G WSG P C
Sbjct: 3109 CKAVQCGNPGTTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNC 3168
Query: 642 EYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNY--RLVGPVRRTCTEEFQWSDSSP 699
I CG P +P + + +G + Y C Y L G RTCT WS P
Sbjct: 3169 TIISCGD-PGIPANGLRYGDDYV-VGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVMP 3226
Query: 700 RCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKV 759
C + C P + S+ R G + G + Y C GY++
Sbjct: 3227 TCRAVTCPTPP---------------------QISNGRLEGTNFDWGFSISYICSPGYEL 3265
Query: 760 IGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWEL 819
++ TC NG WSG P C CG+PG GK + Y + + C+ + L
Sbjct: 3266 SFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQGK--REGKSFIYQSEVSFSCNFPFIL 3323
Query: 820 EGVIRRMCQENGTWSLEPPICKEIT---CPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCE 876
G R+CQ +GTWS P C E T C +P G T +G + C+
Sbjct: 3324 VGSSTRICQADGTWSGSSPHCIEPTQTSCENPGV---PRHGSQNNTFGFQVGSVVQFHCK 3380
Query: 877 RGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCL 936
+G+ L+G TRTC+ W+G P CIP C+ P + V+ G ++ Y C
Sbjct: 3381 KGHLLQGSTTRTCLPDLTWSGIQPECIPHSCKQPETPAHAN-VVGMDLPSHGYTLIYTCQ 3439
Query: 937 SQYQRV-GPFLRKCLDDGRWSGEEPSCE 963
+ G R C D W+G+ P CE
Sbjct: 3440 PGFFLAGGTEHRVCRSDNTWTGKVPICE 3467
Score = 240 bits (587), Expect = 2e-62
Identities = 152/524 (29%), Positives = 226/524 (43%), Gaps = 49/524 (9%)
Query: 470 WCPDPPAVSNASV-TVNGHKAGSLASYTCENGHILSGSTSVTCTLGG----AWSGVPPSC 524
+C P + + + + G + S+ + C+ G L G +S C AW P+C
Sbjct: 2568 YCSTPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPAC 2627
Query: 525 KYVNCGTPTIHKGSFVLINGTTTY--GSIAQFTCEPDYWLNGAE--ELVCNRDGKWSYD- 579
+ ++CG P +L TT Y G+ + C Y L+ E VC DG WS
Sbjct: 2628 QAISCGIPKAPTNGGIL---TTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHN 2684
Query: 580 -IPSCELTSCPEPE---VPSGGY--MEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGE 633
P C + +CP + G + + Y + + F C+ G+ +G ++ C +G
Sbjct: 2685 KTPRCVVVTCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGT 2744
Query: 634 WS--GDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEE 691
WS + P C+ I CG+LPT P G + T GS ++C + LVG R C
Sbjct: 2745 WSWRNERPYCQIISCGELPTPPNGNK--IGTQTSYGSTAIFTCDLGFMLVGSAVRECLSS 2802
Query: 692 FQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKY 751
WS+S RC C P + IV+ + +G Y V Y
Sbjct: 2803 GLWSESETRCLAGHCGIP----ELIVN-----------------GQVIGENYGYRDTVVY 2841
Query: 752 RCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFY 811
+C G+++IG S+ C+ + WSG P+C V CG+PG G+ + N + +
Sbjct: 2842 QCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGHPGSPIYGRTS--GNGFNFNDVVTF 2899
Query: 812 QCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEA 871
C+ + ++G + CQ N WS PP+CK + C DP + + + G
Sbjct: 2900 SCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVV 2959
Query: 872 HYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSV 931
Y C GY L G C GQW+ +P CI IDC PG N V+S FGS+V
Sbjct: 2960 FYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGHPGVPPNA--VLSGEKYTFGSTV 3017
Query: 932 EYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCE-LATNEAVDSGT 974
Y C + +G R C +G WSG +P C AT D GT
Sbjct: 3018 HYSCTGKRSLLGQSSRTCQLNGHWSGSQPHCSGDATGTCGDPGT 3061
Score = 151 bits (365), Expect = 2e-35
Identities = 147/571 (25%), Positives = 220/571 (38%), Gaps = 52/571 (9%)
Query: 411 CGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTC--GDEGIWDGEAPRCLF 468
C P+ + ++ D+ G Y C FTLVGN TC G+ DG P C
Sbjct: 2395 CQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQV 2454
Query: 469 DWCP-DPPAVSNASVTVN-GHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKY 526
CP + + + V ++ G+ C + ++T + +
Sbjct: 2455 -LCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVLQ 2513
Query: 527 VNCGTPTIHKGSFVLINGTTTYGSIAQFTCE-PDYWLNGAEELVCNRDG-KWSYDIPSCE 584
V G P I S VLI+ + Y S T + +L + + N+ G + Y C
Sbjct: 2514 VYDG-PNIQ--SPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAFYCS 2570
Query: 585 LTSCPEPEVPSGGY-MEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDG----EWSGDSP 639
PE P GY + ++S + + C+ G +L+G+ + VC++ W P
Sbjct: 2571 -----TPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVP 2625
Query: 640 TCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRT--CTEEFQWS-- 695
C+ I CG +P P +L +G+ + Y C YRL T C + WS
Sbjct: 2626 ACQAISCG-IPKAPTNG-GILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNH 2683
Query: 696 DSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEK 755
+ +PRC + C S+ HG I G+ Y V + C+
Sbjct: 2684 NKTPRCVVVTCP----------SINSFILEHGRWRIVN------GSHYEYKTKVVFSCDP 2727
Query: 756 GYKVIGESLSTCEDNGQWS--GTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQC 813
GY +G + C NG WS P CQ + CG NG T YG+TA + C
Sbjct: 2728 GYHGLGPASIECLPNGTWSWRNERPYCQIISCGELPTPPNGNKI--GTQTSYGSTAIFTC 2785
Query: 814 DENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHY 873
D + L G R C +G WS C C P + V+ Y
Sbjct: 2786 DLGFMLVGSAVRECLSSGLWSESETRCLAGHCGIPELIVNG----QVIGENYGYRDTVVY 2841
Query: 874 QCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEY 933
QC G+ L G R C W+G +P C+P+ C PG+ G+ NG F V +
Sbjct: 2842 QCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGHPGSPIYGR-TSGNGFN-FNDVVTF 2899
Query: 934 YCLSQYQRVGPFLRKCLDDGRWSGEEPSCEL 964
C Y GP +C + +WS P C++
Sbjct: 2900 SCNIGYLMQGPTKAQCQANRQWSHPPPMCKV 2930
Score = 126 bits (305), Expect = 3e-28
Identities = 73/241 (30%), Positives = 108/241 (44%), Gaps = 7/241 (2%)
Query: 352 TCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNC 411
TC +P ++ N + G ++D G I Y C G+ L C +G WSG P C C
Sbjct: 3232 TCPTPPQISNGRLEGTNFDWGFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQCLPKFC 3291
Query: 412 GGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDW- 470
G P + + +SC F LVG+ R C +G W G +P C+
Sbjct: 3292 GD--PGIPAQGKREGKSFIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQ 3349
Query: 471 --CPDPPAVSNASVTVN-GHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYV 527
C +P + S G + GS+ + C+ GH+L GST+ TC WSG+ P C
Sbjct: 3350 TSCENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECIPH 3409
Query: 528 NCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWL-NGAEELVCNRDGKWSYDIPSCELT 586
+C P + V+ ++G +TC+P ++L G E VC D W+ +P CE
Sbjct: 3410 SCKQPETPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPICEAG 3469
Query: 587 S 587
S
Sbjct: 3470 S 3470
Score = 57.2 bits (132), Expect = 3e-07
Identities = 28/87 (32%), Positives = 47/87 (54%), Gaps = 1/87 (1%)
Query: 571 NRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQ 630
N K Y+ + SC +P +P G D+ + ST++F C++G++L E L+C++
Sbjct: 993 NNGFKIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEK 1052
Query: 631 DGEWSGDSPTCEYIDCGKLPTLPYGTM 657
+ WS PTC+ + CG P GT+
Sbjct: 1053 NHWWSHPLPTCDAL-CGGDVRGPSGTI 1078
Score = 56.0 bits (129), Expect = 7e-07
Identities = 26/74 (35%), Positives = 39/74 (52%), Gaps = 1/74 (1%)
Query: 584 ELTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEY 643
E SC +P P G E + + F C+ G +LIGE ++VCQ++ +WS + P C +
Sbjct: 660 EKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIF 719
Query: 644 IDCGKLPTLPYGTM 657
C T P GT+
Sbjct: 720 -PCLSNFTAPMGTV 732
Score = 55.6 bits (128), Expect = 9e-07
Identities = 140/626 (22%), Positives = 221/626 (35%), Gaps = 66/626 (10%)
Query: 352 TCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNC 411
+CG P L G+ + + ++C G L+G+KS C+++ WS P C +
Sbjct: 663 SCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPCL 722
Query: 412 GGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNP-ERTCGDEGIWDGEAPRCLFDW 470
T G V D +G +C +T++ +P R +D E+ FD+
Sbjct: 723 SNFT-APMGTVLSPDYPEGYGNN--LNC--IWTIISDPGSRIHLSFNDFDLESQ---FDF 774
Query: 471 CPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVP-PSCKYVNC 529
S S + + S+ N HIL ++ G + + + C
Sbjct: 775 LAVKDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTFGHNEC 834
Query: 530 GTPTIHKGSFVLINGTTTYGSIAQFTCEPDY-WLNGAEELVC-NRDGK--WSYDIPSCEL 585
P I + GS CE + G E + C DGK WS IP C
Sbjct: 835 PDPGIPINA-RRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKCGA 893
Query: 586 TSCPEPEVPSGGYME-AFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYI 644
PSG + + Y ++N CE + EP + E + +
Sbjct: 894 PCGGHFSAPSGVILSPGWPGYYKDSLN--CE--WVIEAEPGHSIKITFERFQTELNYDVL 949
Query: 645 DCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEI 704
+ P L + NG T + + S Y L F+ S
Sbjct: 950 EVHDGPNLLSPLLGSYNG-TQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTY 1008
Query: 705 RCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESL 764
C DP + + R +GH + IG+ V + C+ GY++ E
Sbjct: 1009 SCLDP--------GIPVHGRRYGH-------------DFSIGSTVSFSCDSGYRLSHEEP 1047
Query: 765 STCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIR 824
CE N WS PTC + CG R +G + P FY + C W ++
Sbjct: 1048 LLCEKNHWWSHPLPTCDAL-CGGDVRGPSGTILSPGYPEFYPNS--LNC--TWTVDVTHG 1102
Query: 825 RMCQEN-GTWSLEPP-----ICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERG 878
+ Q N T+ LE I + + P A++ GS L T++ G +++ +
Sbjct: 1103 KGVQFNFHTFHLEDHHDYLLITENGSFTQPLARL-TGSDL---PPTINAGLYGNFRAQLR 1158
Query: 879 YNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQ 938
+ + IS +N T C PG + G + N G ++ + C S
Sbjct: 1159 F-----ISDFSISYEGFNITFSEYNLEPCEDPGIPQYGSRIGFNFG--IGDTLTFSCSSG 1211
Query: 939 YQRVGPFLRKCLDDGR--WSGEEPSC 962
Y+ G CL GR WS P C
Sbjct: 1212 YRLEGTSEIICLGGGRRVWSAPLPRC 1237
Score = 50.8 bits (116), Expect = 3e-05
Identities = 59/248 (23%), Positives = 99/248 (39%), Gaps = 22/248 (8%)
Query: 349 LPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHC--KKDG--FWSGAPP 404
L +C P ++N T LG DY +GS + Y C G++L G + C DG W+ A P
Sbjct: 1697 LRESCFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALP 1756
Query: 405 SCKYVNCGGLTPIEDGDVALIDNRTTHGARALYSCREN--FTLVGNPERTCGDEGIWDGE 462
SC + CG + +G V L N + YS N +++ E + ++
Sbjct: 1757 SC-HAPCGSRSTGSEGTV-LSPNYPKN-----YSVGHNCVYSIAVPKEFVVFGQFVFFQT 1809
Query: 463 APRCLFDWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGG---AWSG 519
+ + + P S+ +++G +G + N + ++ T G +
Sbjct: 1810 SLHDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVYQA 1869
Query: 520 VPPSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVC----NRDGK 575
VP + P G I GS F C P Y L+G+ + C N +
Sbjct: 1870 VPRTSSTQCSSVPEPRFGR--RIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQ 1927
Query: 576 WSYDIPSC 583
W+ +P+C
Sbjct: 1928 WNDSLPTC 1935
Score = 48.4 bits (110), Expect = 1e-04
Identities = 24/73 (32%), Positives = 34/73 (46%), Gaps = 4/73 (5%)
Query: 588 CPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGE----WSGDSPTCEY 643
CP+P P G D+ + ST+ F C+ + L G ++ CQ+ E WS P C+
Sbjct: 486 CPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKV 545
Query: 644 IDCGKLPTLPYGT 656
CG P GT
Sbjct: 546 KTCGSNLQGPSGT 558
Score = 48.4 bits (110), Expect = 1e-04
Identities = 27/76 (35%), Positives = 37/76 (48%), Gaps = 3/76 (3%)
Query: 584 ELTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQ--DGEWSGDSPTC 641
+L SCP+P G++ D+ V TI+F C G+ LIG L C W+ P C
Sbjct: 2220 QLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRC 2279
Query: 642 EYIDCGKLPTLPYGTM 657
E + CG T GT+
Sbjct: 2280 EAL-CGGNITAMNGTI 2294
Score = 48.0 bits (109), Expect = 2e-04
Identities = 28/88 (31%), Positives = 39/88 (44%), Gaps = 5/88 (5%)
Query: 471 CPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTC----TLGGAWSGVPPSCKY 526
CPDP N + GS ++C+ ++L G+ S+TC + AWS P CK
Sbjct: 486 CPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKV 545
Query: 527 VNCGTPTI-HKGSFVLINGTTTYGSIAQ 553
CG+ G+F N Y S AQ
Sbjct: 546 KTCGSNLQGPSGTFTSPNFPFQYDSNAQ 573
Score = 47.6 bits (108), Expect = 2e-04
Identities = 23/57 (40%), Positives = 26/57 (45%), Gaps = 3/57 (5%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
CGHP VPPNA +S E G+ Y C L G R C L G W+ P C
Sbjct: 2995 CGHPGVPPNAVLS---GEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHWSGSQPHC 3048
Score = 46.0 bits (104), Expect = 7e-04
Identities = 22/65 (33%), Positives = 30/65 (46%), Gaps = 3/65 (4%)
Query: 585 LTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQD--GEWSGDSPTCE 642
L SCPEP+ PS G Y V ++F C+ G+ L G ++ C W+ P C
Sbjct: 2049 LDSCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPIC- 2107
Query: 643 YIDCG 647
CG
Sbjct: 2108 LAQCG 2112
Score = 45.6 bits (103), Expect = 0.001
Identities = 107/466 (22%), Positives = 166/466 (35%), Gaps = 57/466 (12%)
Query: 471 CPDPPAVSNASVTVNGHKAGSLASYTCENGHI-LSGSTSVTCTLGGA---WSGVPPSCKY 526
CPDP NA + + GS S CE G I G+ ++TC L WSG+ P C
Sbjct: 834 CPDPGIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKCG- 892
Query: 527 VNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAE-----ELVCNR-DGKWSYDI 580
CG +L G Y CE W+ AE ++ R + +YD+
Sbjct: 893 APCGGHFSAPSGVILSPGWPGYYK-DSLNCE---WVIEAEPGHSIKITFERFQTELNYDV 948
Query: 581 PSCELTSCPEPEVP-SGGYM-EAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDS 638
E+ P P G Y ++ S+ NF + L N + +S
Sbjct: 949 --LEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFI----YLLFTTDNSRSNNGFKIHYES 1002
Query: 639 PTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSS 698
T C P +P + + +GS + +SC + YRL C + WS
Sbjct: 1003 VTVNTYSCLD-PGIPVHGRRYGHDFS-IGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPL 1060
Query: 699 PRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYK 758
P C+ + C + + G + ++L + DV + G V++ +
Sbjct: 1061 PTCDAL-CGGDVRGPSGTILSPGYPEFYPNSL-NCTWTVDVTH----GKGVQFNFHTFHL 1114
Query: 759 VIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWE 818
+NG S T P + P I G L N + A + D +
Sbjct: 1115 EDHHDYLLITENG--SFTQPLARLTGSDLPPTINAG---LYGN---FRAQLRFISDFSIS 1166
Query: 819 LEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERG 878
EG + N LEP C DP + GS + IG + C G
Sbjct: 1167 YEGFNITFSEYN----LEP-------CEDPGIP-QYGSR---IGFNFGIGDTLTFSCSSG 1211
Query: 879 YNLKGHQTRTCISKGQ--WNGTVPVCIPIDCRSPGNIENGKIVISN 922
Y L+G C+ G+ W+ +P C+ +C + G ++ N
Sbjct: 1212 YRLEGTSEIICLGGGRRVWSAPLPRCV-AECGASATNNEGILLSPN 1256
Score = 44.8 bits (101), Expect = 0.002
Identities = 21/58 (36%), Positives = 27/58 (46%), Gaps = 1/58 (1%)
Query: 2 CGHPAVPPNA-RVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C P +P N+ R S N GT+ Y+C+ GY LFG+ C G W P C
Sbjct: 2933 CSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPEC 2990
Score = 44.4 bits (100), Expect = 0.002
Identities = 54/230 (23%), Positives = 82/230 (35%), Gaps = 15/230 (6%)
Query: 739 VGNTYRIGALVKYRCEKGYKVIGESLSTCED--NGQWSGTTPTCQYVDCGNPGRIENGKV 796
+GN + +G + + C GY +IG S TC + W+ P C+ + CG NG +
Sbjct: 2236 IGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEAL-CGGNITAMNGTI 2294
Query: 797 TLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGS 856
P Y F C W + N T PI IT D Q
Sbjct: 2295 YSPGYPDEY--PNFQDC--FWLVRVPPGNGIYINFTVLQTEPIYDFITVWDGPDQNSPQI 2350
Query: 857 GLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENG 916
G + L E+ Y +K H T + G + + C+ P + N
Sbjct: 2351 GQFSGNTAL----ESVYSTSNQILIKFHSDFT--TSGFFVLSYHAYQLRVCQPPPPVPNA 2404
Query: 917 KIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGR--WSGEEPSCEL 964
+I+ + G + Y CL + VG + C R G P C++
Sbjct: 2405 EILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQV 2454
Score = 43.6 bits (98), Expect = 0.004
Identities = 26/93 (27%), Positives = 43/93 (46%), Gaps = 4/93 (4%)
Query: 333 NDVGCNLDYLHWICQ-YLPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSR 391
+D N H + Q Y +C P N ++GND+ VG I ++C G+ L+G+ +
Sbjct: 2203 SDYSQNKQGFHIVYQAYQLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSAL 2262
Query: 392 HCKK--DGFWSGAPPSCKYVNCGGLTPIEDGDV 422
C W+ P C+ + CGG +G +
Sbjct: 2263 TCLHGVSRNWNHPLPRCEAL-CGGNITAMNGTI 2294
Score = 43.2 bits (97), Expect = 0.005
Identities = 22/64 (34%), Positives = 34/64 (53%), Gaps = 4/64 (6%)
Query: 353 CGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKK--DGF--WSGAPPSCKY 408
C P + N +G+D+ +GS + + C E ++L G KS C++ + F WS P CK
Sbjct: 486 CPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKV 545
Query: 409 VNCG 412
CG
Sbjct: 546 KTCG 549
Score = 42.3 bits (95), Expect = 0.009
Identities = 33/124 (26%), Positives = 61/124 (49%), Gaps = 10/124 (8%)
Query: 726 HGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDC 785
H + RT + V T+R+ + ++ +G+K+ ++ + + G T + C
Sbjct: 431 HAEQIERTKELAVV--THRVKKAIDFK-SRGFKLFPGKDNSNKFSILNEGGIKTASNL-C 486
Query: 786 GNPGRIENGKVTLPSNATFYGATAFYQCDENWELEG----VIRRMCQENGTWSLEPPICK 841
+PG ENGK + S+ + G+T + CDE++ L+G +R+ + WS P+CK
Sbjct: 487 PDPGEPENGK-RIGSDFSL-GSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCK 544
Query: 842 EITC 845
TC
Sbjct: 545 VKTC 548
Score = 42.3 bits (95), Expect = 0.009
Identities = 19/62 (30%), Positives = 35/62 (56%), Gaps = 6/62 (9%)
Query: 844 TCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCI--SKGQWNGTVPV 901
+CP+P SG+ + + +G +QC++GY+L+GH TC+ +WN +P+
Sbjct: 2051 SCPEPQTP---SSGIKIGDRYM-VGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPI 2106
Query: 902 CI 903
C+
Sbjct: 2107 CL 2108
Score = 42.3 bits (95), Expect = 0.009
Identities = 20/57 (35%), Positives = 24/57 (42%), Gaps = 3/57 (5%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
CG P P + E N + Y CD GY L G+ +R C G WT P C
Sbjct: 3056 CGDPGTPGHGS---RQESNFRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQPEC 3109
Score = 41.9 bits (94), Expect = 0.012
Identities = 22/59 (37%), Positives = 29/59 (49%), Gaps = 5/59 (8%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGY--ELFGARQRECTLRGDWTLEPPFC 58
CG P +P N + ++ V G Y C GY EL G+R R CT+ G W+ P C
Sbjct: 3173 CGDPGIPANG---LRYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVMPTC 3228
Score = 41.1 bits (92), Expect = 0.021
Identities = 49/223 (21%), Positives = 81/223 (36%), Gaps = 15/223 (6%)
Query: 432 GARALYSCRENFTLVGNPERTC--GDEGIWDGEAPRCLFDWCPDPPAVSNASVTVN-GHK 488
G +SC + L G E C G +W PRC+ + C A +N + ++ +
Sbjct: 1201 GDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVAE-C-GASATNNEGILLSPNYP 1258
Query: 489 AGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTIHK-GSFVLINGTTT 547
++ C + + + K + T H G+F G +
Sbjct: 1259 LNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDGKDKTTHLLGAFT---GASM 1315
Query: 548 YGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGY-MEAFDYYV 606
G T WL + +G + S EL+ C +P +P GY + ++
Sbjct: 1316 RGLTLSSTSN-QLWLEFNSDTEGTDEG-FQLVYTSFELSHCEDPGIPQFGYKISDQGHFA 1373
Query: 607 HSTINFHCEAGHKLIGEPNLVCQ--QDGEWSGDSPTCEYIDCG 647
STI + C G+ L G L C + W P+C +CG
Sbjct: 1374 GSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSC-IAECG 1415
Score = 41.1 bits (92), Expect = 0.021
Identities = 25/75 (33%), Positives = 36/75 (48%), Gaps = 5/75 (6%)
Query: 587 SCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVC--QQDGE--WSGDSPTCE 642
SC +P G DY + ST+ ++C+AG+ L G L C DG W+ P+C
Sbjct: 1700 SCFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSC- 1758
Query: 643 YIDCGKLPTLPYGTM 657
+ CG T GT+
Sbjct: 1759 HAPCGSRSTGSEGTV 1773
Score = 41.1 bits (92), Expect = 0.021
Identities = 22/66 (33%), Positives = 35/66 (53%), Gaps = 5/66 (7%)
Query: 739 VGNTYRIGALVKYRCEKGYKVIGESLSTC--EDNGQ--WSGTTPTCQYVDCGNPGRIENG 794
+G Y++G+ V Y C+ GY + G S TC D+G+ W+ P+C + CG+ G
Sbjct: 1713 LGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSC-HAPCGSRSTGSEG 1771
Query: 795 KVTLPS 800
V P+
Sbjct: 1772 TVLSPN 1777
Score = 41.1 bits (92), Expect = 0.021
Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 9/77 (11%)
Query: 471 CPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGA--WSGVPPSCKYVN 528
CPDP N V N G S+ C G+ L G++++TC G + W+ P C+ +
Sbjct: 2224 CPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEAL- 2282
Query: 529 CGTPTIHKGSFVLINGT 545
CG G+ +NGT
Sbjct: 2283 CG------GNITAMNGT 2293
Score = 41.1 bits (92), Expect = 0.021
Identities = 23/77 (29%), Positives = 35/77 (45%), Gaps = 3/77 (3%)
Query: 1 RCGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGT 60
+CG+P N +V + + +Y C EGY L G R+CT G W+ P C T
Sbjct: 3113 QCGNPGTTANGKVF--RIDGTTFSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNC-T 3169
Query: 61 NVAFRKPANQSTTVRGG 77
++ P + +R G
Sbjct: 3170 IISCGDPGIPANGLRYG 3186
Score = 39.9 bits (89), Expect = 0.049
Identities = 21/62 (33%), Positives = 32/62 (51%), Gaps = 5/62 (8%)
Query: 542 INGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGK----WSYDIPSCELTSC-PEPEVPSG 596
I + GS QF+C+ DY L GA+ + C R + WS P C++ +C + PSG
Sbjct: 498 IGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSG 557
Query: 597 GY 598
+
Sbjct: 558 TF 559
Score = 39.1 bits (87), Expect = 0.085
Identities = 21/83 (25%), Positives = 41/83 (49%), Gaps = 6/83 (7%)
Query: 735 DNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQ----WSGTTPTCQYVDCGNPGR 790
+ + +G+ + +G+ V++ C++ Y + G TC+ + WS P C+ CG+ +
Sbjct: 494 NGKRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQ 553
Query: 791 IENGKVTLPSNATFYGATAFYQC 813
+G T P+ Y + A QC
Sbjct: 554 GPSGTFTSPNFPFQYDSNA--QC 574
Score = 39.1 bits (87), Expect = 0.085
Identities = 48/229 (20%), Positives = 78/229 (34%), Gaps = 16/229 (6%)
Query: 739 VGNTYRIGALVKYRCEKGYKVIGESLSTCEDN--GQWSGTTPTCQYVDCGNPGRIENGKV 796
+G+ Y +G +V ++C++GY + G S TC +W+ P C CG +G +
Sbjct: 2064 IGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPIC-LAQCGGAMSDFSGVI 2122
Query: 797 TLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGS 856
P Y ++ N + + T ++ + + S I S
Sbjct: 2123 LSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLS 2182
Query: 857 GLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENG 916
G + +S S E Y+ Q C P NG
Sbjct: 2183 GPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQ---------SCPDPRPFRNG 2233
Query: 917 KIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLD--DGRWSGEEPSCE 963
VI N T+ G ++ + C Y +G CL W+ P CE
Sbjct: 2234 -FVIGNDFTV-GQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCE 2280
Score = 38.7 bits (86), Expect = 0.11
Identities = 19/64 (29%), Positives = 30/64 (46%), Gaps = 3/64 (4%)
Query: 469 DWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGA--WSGVPPSCKY 526
D CP+P S+ + + G + S+ C+ G+ L G + +TC G W+ P C
Sbjct: 2050 DSCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPIC-L 2108
Query: 527 VNCG 530
CG
Sbjct: 2109 AQCG 2112
Score = 37.9 bits (84), Expect = 0.20
Identities = 24/88 (27%), Positives = 43/88 (48%), Gaps = 9/88 (10%)
Query: 343 HWICQYLPPT----CGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCK---- 394
H++ Q +P T C S + +GN++ VGS +++ C G++L G + C+
Sbjct: 1864 HFVYQAVPRTSSTQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPN 1923
Query: 395 KDGFWSGAPPSCKYVNCGGLTPIEDGDV 422
W+ + P+C V CGG+ G +
Sbjct: 1924 SLAQWNDSLPTC-IVPCGGILTKRKGTI 1950
Score = 37.9 bits (84), Expect = 0.20
Identities = 21/67 (31%), Positives = 30/67 (44%), Gaps = 5/67 (7%)
Query: 737 RDVGNTYRIGALVKYRCEKGYKVIGESLSTCE----DNGQWSGTTPTCQYVDCGNPGRIE 792
R +GN + +G+ V + C GY + G CE QW+ + PTC V CG
Sbjct: 1888 RRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTC-IVPCGGILTKR 1946
Query: 793 NGKVTLP 799
G + P
Sbjct: 1947 KGTILSP 1953
Score = 37.9 bits (84), Expect = 0.20
Identities = 23/82 (28%), Positives = 33/82 (40%), Gaps = 4/82 (4%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTN 61
CGHP P R S N N + + C+ GY + G + +C W+ PP C
Sbjct: 2875 CGHPGSPIYGRTS-GNGFNF--NDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKV- 2930
Query: 62 VAFRKPANQSTTVRGGAAANGN 83
V P + + R +GN
Sbjct: 2931 VNCSDPGIPANSKRESKIEHGN 2952
Score = 37.5 bits (83), Expect = 0.26
Identities = 19/51 (37%), Positives = 26/51 (50%), Gaps = 5/51 (9%)
Query: 867 IGGEAHYQCERGYNLKGHQTRTCI----SKGQWNGTVPVC-IPIDCRSPGN 912
+G Y C+ GY L+G+ T TCI + WN +P C P RS G+
Sbjct: 1719 LGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCGSRSTGS 1769
Score = 36.7 bits (81), Expect = 0.45
Identities = 26/85 (30%), Positives = 37/85 (43%), Gaps = 9/85 (10%)
Query: 844 TCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISK----GQWNGTV 899
+C +P K G+L T +G + Y C GY L GH TCI+ W+ V
Sbjct: 177 SCGNPGVPPK---GVLYGTR-FDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPV 232
Query: 900 PVCIPIDCRSPGNIENGKIVISNGS 924
P+C D G + +IS+ S
Sbjct: 233 PICRAEDA-CGGTMRGSSGIISSPS 256
Score = 36.7 bits (81), Expect = 0.45
Identities = 19/57 (33%), Positives = 27/57 (47%), Gaps = 3/57 (5%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
CG PPN I + + G+ A++ CD G+ L G+ REC G W+ C
Sbjct: 2759 CGELPTPPNGN-KIGTQTSY--GSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRC 2812
Score = 36.3 bits (80), Expect = 0.60
Identities = 20/65 (30%), Positives = 27/65 (41%), Gaps = 4/65 (6%)
Query: 586 TSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGE---WSGDSPTCE 642
T+C +P VP G T+ F C+ G++L GE + C Q W P C
Sbjct: 1526 TACRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVC- 1584
Query: 643 YIDCG 647
CG
Sbjct: 1585 IAPCG 1589
Score = 36.3 bits (80), Expect = 0.60
Identities = 24/60 (40%), Positives = 30/60 (50%), Gaps = 6/60 (10%)
Query: 907 CRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCL--DDGR--WSGEEPSC 962
C PGNI NG + + GS+V YYC + Y G C+ DDGR W+ PSC
Sbjct: 1701 CFDPGNIMNGTRLGMDYK--LGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSC 1758
Score = 35.5 bits (78), Expect = 1.0
Identities = 20/67 (29%), Positives = 30/67 (44%), Gaps = 5/67 (7%)
Query: 352 TCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGF----WSGAPPSCK 407
+CG+P + G +DVG +I Y C G++L G C + W P C+
Sbjct: 177 SCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICR 236
Query: 408 YVN-CGG 413
+ CGG
Sbjct: 237 AEDACGG 243
Score = 35.5 bits (78), Expect = 1.0
Identities = 20/66 (30%), Positives = 29/66 (43%), Gaps = 5/66 (7%)
Query: 740 GNTYRIGALVKYRCEKGYKVIGESLSTCEDN----GQWSGTTPTCQYVD-CGNPGRIENG 794
G + +G ++Y C GY + G TC N W P C+ D CG R +G
Sbjct: 191 GTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDACGGTMRGSSG 250
Query: 795 KVTLPS 800
++ PS
Sbjct: 251 IISSPS 256
Score = 35.5 bits (78), Expect = 1.0
Identities = 22/82 (26%), Positives = 35/82 (42%), Gaps = 5/82 (6%)
Query: 580 IPSCELTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQ----QDGEWS 635
+P T C P G ++ V S++ F C G+ L G + C+ +W+
Sbjct: 1870 VPRTSSTQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWN 1929
Query: 636 GDSPTCEYIDCGKLPTLPYGTM 657
PTC + CG + T GT+
Sbjct: 1930 DSLPTC-IVPCGGILTKRKGTI 1950
Score = 35.1 bits (77), Expect = 1.4
Identities = 21/67 (31%), Positives = 26/67 (38%), Gaps = 5/67 (7%)
Query: 586 TSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVC----QQDGEWSGDSPTC 641
+SC P VP G + + V I + C G+ L G P L C W P C
Sbjct: 176 SSCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPIC 235
Query: 642 EYID-CG 647
D CG
Sbjct: 236 RAEDACG 242
Score = 35.1 bits (77), Expect = 1.4
Identities = 21/60 (35%), Positives = 25/60 (41%), Gaps = 6/60 (10%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTL---RGDWTLEPPFC 58
C P VP N N + G V++CD GYEL G + C R W PP C
Sbjct: 1528 CRDPGVPMNGT---RNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVC 1584
Score = 35.1 bits (77), Expect = 1.4
Identities = 20/59 (33%), Positives = 27/59 (45%), Gaps = 5/59 (8%)
Query: 785 CGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMC---QENGTWSLEPPIC 840
C +PG NG T + G T +QCD +EL+G R C + W PP+C
Sbjct: 1528 CRDPGVPMNG--TRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVC 1584
Score = 34.7 bits (76), Expect = 1.8
Identities = 20/74 (27%), Positives = 28/74 (37%), Gaps = 4/74 (5%)
Query: 471 CPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTL---GGAWSGVPPSCKYV 527
C DP N + +G + G + C+ G+ L G +TC W PP C
Sbjct: 1528 CRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVC-IA 1586
Query: 528 NCGTPTIHKGSFVL 541
CG F+L
Sbjct: 1587 PCGGNLTGSSGFIL 1600
Score = 34.7 bits (76), Expect = 1.8
Identities = 19/59 (32%), Positives = 25/59 (42%), Gaps = 3/59 (5%)
Query: 528 NCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVC--NRDGKWSYDIPSCE 584
+C P + FV+ N T G F C P Y L G L C W++ +P CE
Sbjct: 2223 SCPDPRPFRNGFVIGNDFTV-GQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCE 2280
Score = 33.9 bits (74), Expect = 3.2
Identities = 19/45 (42%), Positives = 23/45 (51%), Gaps = 4/45 (8%)
Query: 666 LGSVIQYSCTTNYRLVGPVRRTC---TEEF-QWSDSSPRCEEIRC 706
LGS +Q+SC +Y L G TC E F WSD P C+ C
Sbjct: 504 LGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTC 548
Score = 33.5 bits (73), Expect = 4.2
Identities = 24/83 (28%), Positives = 35/83 (42%), Gaps = 4/83 (4%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTN 61
CG P + N +V EN VY+C+ G+ L G+ R C +W+ + P C
Sbjct: 2817 CGIPELIVNGQVI---GENYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSC-VP 2872
Query: 62 VAFRKPANQSTTVRGGAAANGND 84
V+ P + G N ND
Sbjct: 2873 VSCGHPGSPIYGRTSGNGFNFND 2895
Score = 33.1 bits (72), Expect = 5.6
Identities = 15/39 (38%), Positives = 22/39 (56%), Gaps = 3/39 (7%)
Query: 868 GGEAHYQCERGYNLKGHQTRTCI---SKGQWNGTVPVCI 903
G +QC+ GY L+G + TCI ++ W + PVCI
Sbjct: 1547 GDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCI 1585
Score = 33.1 bits (72), Expect = 5.6
Identities = 20/59 (33%), Positives = 26/59 (44%), Gaps = 4/59 (6%)
Query: 410 NCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTC--GDEGIWDGEAPRC 466
+C P +G V I N T G + C +TL+GN TC G W+ PRC
Sbjct: 2223 SCPDPRPFRNGFV--IGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRC 2279
>AB067481-1|BAB67787.2| 2977|Homo sapiens KIAA1894 protein protein.
Length = 2977
Score = 335 bits (823), Expect = 6e-91
Identities = 195/625 (31%), Positives = 272/625 (43%), Gaps = 42/625 (6%)
Query: 346 CQYLPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPS 405
CQ + +CG N +G GS ++ C G ML+G R C G WS +
Sbjct: 2024 CQII--SCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSESETR 2081
Query: 406 CKYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPR 465
C +CG I +G V I + +Y C F L+G+ R C + W G+ P
Sbjct: 2082 CLAGHCGIPELIVNGQV--IGENYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPS 2139
Query: 466 CLFDWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCK 525
C+ C P + + NG + +++C G+++ G T C WS PP CK
Sbjct: 2140 CVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCK 2199
Query: 526 YVNC---GTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPS 582
VNC G P K + +G TYG++ + C P Y+L G+ L+C +G+W +P
Sbjct: 2200 VVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPE 2259
Query: 583 CELTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCE 642
C + C P VP + Y ST+++ C L+G+ + CQ +G WSG P C
Sbjct: 2260 CIMIDCGHPGVPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHWSGSQPHCS 2319
Query: 643 ---YIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSP 699
CG T +G+ + N T S ++Y+C T Y L G RTC W+ P
Sbjct: 2320 GDATGTCGDPGTPGHGSRQESNFRTK--STVRYACDTGYILHGSEERTCLANGSWTGRQP 2377
Query: 700 RCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKV 759
C+ ++C +P T N + R G T+ + V Y C +GY +
Sbjct: 2378 ECKAVQCGNP--------GTTANGKVF----------RIDGTTF--SSSVIYSCMEGYIL 2417
Query: 760 IGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENW-- 817
G S+ C NG WSGT P C + CG+PG NG + G Y C +
Sbjct: 2418 SGPSVRQCTANGTWSGTLPNCTIISCGDPGIPANG--LRYGDDYVVGQNVSYMCQPGYTM 2475
Query: 818 ELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCER 877
EL G R C NGTWS P C+ +TCP P QI G + + G Y C
Sbjct: 2476 ELNGSRIRTCTINGTWSGVMPTCRAVTCPTP-PQISNGR---LEGTNFDWGFSISYICSP 2531
Query: 878 GYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLS 937
GY L TC+ G W+G VP C+P C PG GK S ++ S V + C
Sbjct: 2532 GYELSFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQGK--REGKSFIYQSEVSFSCNF 2589
Query: 938 QYQRVGPFLRKCLDDGRWSGEEPSC 962
+ VG R C DG WSG P C
Sbjct: 2590 PFILVGSSTRICQADGTWSGSSPHC 2614
Score = 333 bits (819), Expect = 2e-90
Identities = 195/606 (32%), Positives = 280/606 (46%), Gaps = 40/606 (6%)
Query: 366 GNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWS--GAPPSCKYVNCGGLTPIEDGDVA 423
G+ Y+ +++V+ C G+ LG S C +G WS P C+ ++CG L +G+
Sbjct: 1982 GSHYEYKTKVVFSCDPGYHGLGPASIECLPNGTWSWRNERPYCQIISCGELPTPPNGNK- 2040
Query: 424 LIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVT 483
I +T++G+ A+++C F LVG+ R C G+W RCL C P + N V
Sbjct: 2041 -IGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRCLAGHCGIPELIVNGQVI 2099
Query: 484 VNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTIHKGSFVLIN 543
+ Y C G L GS+ C WSG PSC V+CG P N
Sbjct: 2100 GENYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGHPGSPIYGRTSGN 2159
Query: 544 GTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEA-- 601
G + + F+C Y + G + C + +WS+ P C++ +C +P +P+ E+
Sbjct: 2160 GFN-FNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGIPANSKRESKI 2218
Query: 602 -FDYYVHSTINFH-CEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMEL 659
+ + T+ F+ C G+ L G L+CQ +G+W P C IDCG P +P +
Sbjct: 2219 EHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGH-PGVPPNAV-- 2275
Query: 660 LNGTTH-LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVS 718
L+G + GS + YSCT L+G RTC WS S P C
Sbjct: 2276 LSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHWSGSQPHCSG-----------DATG 2324
Query: 719 VTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTP 778
G+ + GH +R N +R + V+Y C+ GY + G TC NG W+G P
Sbjct: 2325 TCGDPGTPGH------GSRQESN-FRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQP 2377
Query: 779 TCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPP 838
C+ V CGNPG NGKV TF ++ Y C E + L G R C NGTWS P
Sbjct: 2378 ECKAVQCGNPGTTANGKVFRIDGTTF-SSSVIYSCMEGYILSGPSVRQCTANGTWSGTLP 2436
Query: 839 ICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGY--NLKGHQTRTCISKGQWN 896
C I+C DP I A L +G Y C+ GY L G + RTC G W+
Sbjct: 2437 NCTIISCGDPG--IPANG--LRYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTINGTWS 2492
Query: 897 GTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWS 956
G +P C + C +P I NG++ +N +G S+ Y C Y+ P + C+ +G WS
Sbjct: 2493 GVMPTCRAVTCPTPPQISNGRLEGTNFD--WGFSISYICSPGYELSFPAVLTCVGNGTWS 2550
Query: 957 GEEPSC 962
GE P C
Sbjct: 2551 GEVPQC 2556
Score = 307 bits (754), Expect = 1e-82
Identities = 195/638 (30%), Positives = 279/638 (43%), Gaps = 50/638 (7%)
Query: 347 QYLPPTCGSPDKLLNTTILGNDY-DVGSRIVYKCPEGHMLLGDKSRHCKKDGF----WSG 401
+Y+ C +P+ + I+ + S + + C G L+G S C+K + W
Sbjct: 1833 RYIAFYCSTPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDA 1892
Query: 402 APPSCKYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERT--CGDEGIW 459
P+C+ ++CG +G + D G R Y C + + L T C +G W
Sbjct: 1893 PVPACQAISCGIPKAPTNGGILTTDYLV--GTRVTYFCNDGYRLSSKELTTAVCQSDGTW 1950
Query: 460 D--GEAPRCLFDWCPDPPAV---SNASVTVNG--HKAGSLASYTCENGHILSGSTSVTCT 512
+ PRC+ CP + VNG ++ + ++C+ G+ G S+ C
Sbjct: 1951 SNHNKTPRCVVVTCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECL 2010
Query: 513 LGGAWS--GVPPSCKYVNCG-TPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELV 569
G WS P C+ ++CG PT G+ I T+YGS A FTC+ + L G+
Sbjct: 2011 PNGTWSWRNERPYCQIISCGELPTPPNGN--KIGTQTSYGSTAIFTCDLGFMLVGSAVRE 2068
Query: 570 CNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQ 629
C G WS C C PE+ G + +Y T+ + C G +LIG +CQ
Sbjct: 2069 CLSSGLWSESETRCLAGHCGIPELIVNGQVIGENYGYRDTVVYQCNPGFRLIGSSVRICQ 2128
Query: 630 QDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCT 689
QD WSG P+C + CG + YG NG + V+ +SC Y + GP + C
Sbjct: 2129 QDHNWSGQLPSCVPVSCGHPGSPIYGRTS-GNG-FNFNDVVTFSCNIGYLMQGPTKAQCQ 2186
Query: 690 EEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALV 749
QWS P C+ + CSDP + S + + GN + G +V
Sbjct: 2187 ANRQWSHPPPMCKVVNCSDPGIPANS----------------KRESKIEHGN-FTYGTVV 2229
Query: 750 KYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATA 809
Y C GY + G S+ C+ NGQW P C +DCG+PG N L +G+T
Sbjct: 2230 FYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGHPGVPPN--AVLSGEKYTFGSTV 2287
Query: 810 FYQCDENWELEGVIRRMCQENGTWSLEPPICK---EITCPDPSAQIKAGSGLLVVTSTLS 866
Y C L G R CQ NG WS P C TC DP G G S
Sbjct: 2288 HYSCTGKRSLLGQSSRTCQLNGHWSGSQPHCSGDATGTCGDPGT---PGHGSR-QESNFR 2343
Query: 867 IGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTL 926
Y C+ GY L G + RTC++ G W G P C + C +PG NGK+ +G+T
Sbjct: 2344 TKSTVRYACDTGYILHGSEERTCLANGSWTGRQPECKAVQCGNPGTTANGKVFRIDGTT- 2402
Query: 927 FGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCEL 964
F SSV Y C+ Y GP +R+C +G WSG P+C +
Sbjct: 2403 FSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNCTI 2440
Score = 280 bits (686), Expect = 2e-74
Identities = 181/637 (28%), Positives = 262/637 (41%), Gaps = 47/637 (7%)
Query: 346 CQYLPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDK--SRHCKKDGFWS--G 401
CQ + +CG P N IL DY VG+R+ Y C +G+ L + + C+ DG WS
Sbjct: 1897 CQAI--SCGIPKAPTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHN 1954
Query: 402 APPSCKYVNCGGLTP--IEDGDVALID-NRTTHGARALYSCRENFTLVGNPERTCGDEGI 458
P C V C + +E G +++ + + + ++SC + +G C G
Sbjct: 1955 KTPRCVVVTCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGT 2014
Query: 459 WD--GEAPRCLFDWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGA 516
W E P C C + P N + GS A +TC+ G +L GS C G
Sbjct: 2015 WSWRNERPYCQIISCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSGL 2074
Query: 517 WSGVPPSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKW 576
WS C +CG P + V I Y + C P + L G+ +C +D W
Sbjct: 2075 WSESETRCLAGHCGIPELIVNGQV-IGENYGYRDTVVYQCNPGFRLIGSSVRICQQDHNW 2133
Query: 577 SYDIPSCELTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSG 636
S +PSC SC P P G + + + F C G+ + G CQ + +WS
Sbjct: 2134 SGQLPSCVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSH 2193
Query: 637 DSPTCEYIDCGK--LPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQW 694
P C+ ++C +P ++ +G G+V+ Y C Y L G C QW
Sbjct: 2194 PPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQW 2253
Query: 695 SDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCE 754
P C I C P V +++S G Y G+ V Y C
Sbjct: 2254 DKPLPECIMIDCGHPGVPPNAVLS---------------------GEKYTFGSTVHYSCT 2292
Query: 755 KGYKVIGESLSTCEDNGQWSGTTPTCQ---YVDCGNPGRIENGKVTLPSNATFYGATAFY 811
++G+S TC+ NG WSG+ P C CG+PG +G + T +T Y
Sbjct: 2293 GKRSLLGQSSRTCQLNGHWSGSQPHCSGDATGTCGDPGTPGHGSRQESNFRT--KSTVRY 2350
Query: 812 QCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEA 871
CD + L G R C NG+W+ P CK + C +P +G + +
Sbjct: 2351 ACDTGYILHGSEERTCLANGSWTGRQPECKAVQCGNPGT---TANGKVFRIDGTTFSSSV 2407
Query: 872 HYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSV 931
Y C GY L G R C + G W+GT+P C I C PG NG + + G +V
Sbjct: 2408 IYSCMEGYILSGPSVRQCTANGTWSGTLPNCTIISCGDPGIPANG--LRYGDDYVVGQNV 2465
Query: 932 EYYCLSQY--QRVGPFLRKCLDDGRWSGEEPSCELAT 966
Y C Y + G +R C +G WSG P+C T
Sbjct: 2466 SYMCQPGYTMELNGSRIRTCTINGTWSGVMPTCRAVT 2502
Score = 277 bits (679), Expect = 2e-73
Identities = 181/628 (28%), Positives = 259/628 (41%), Gaps = 44/628 (7%)
Query: 349 LPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKY 408
+P +CG P + GN ++ + + C G+++ G C+ + WS PP CK
Sbjct: 2141 VPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKV 2200
Query: 409 VNCG--GLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRC 466
VNC G+ + + T+G Y C + L G+ C G WD P C
Sbjct: 2201 VNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPEC 2260
Query: 467 LFDWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCK- 525
+ C P NA ++ + GS Y+C L G +S TC L G WSG P C
Sbjct: 2261 IMIDCGHPGVPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHWSGSQPHCSG 2320
Query: 526 --YVNCGTP-TIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPS 582
CG P T GS N T S ++ C+ Y L+G+EE C +G W+ P
Sbjct: 2321 DATGTCGDPGTPGHGSRQESNFRTK--STVRYACDTGYILHGSEERTCLANGSWTGRQPE 2378
Query: 583 CELTSCPEPEVPSGGYMEAFDYYVHST-INFHCEAGHKLIGEPNLVCQQDGEWSGDSPTC 641
C+ C P + G + D S+ + + C G+ L G C +G WSG P C
Sbjct: 2379 CKAVQCGNPGTTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNC 2438
Query: 642 EYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNY--RLVGPVRRTCTEEFQWSDSSP 699
I CG P +P + + +G + Y C Y L G RTCT WS P
Sbjct: 2439 TIISCGD-PGIPANGLRYGDDYV-VGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVMP 2496
Query: 700 RCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKV 759
C + C P + S+ R G + G + Y C GY++
Sbjct: 2497 TCRAVTCPTPP---------------------QISNGRLEGTNFDWGFSISYICSPGYEL 2535
Query: 760 IGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWEL 819
++ TC NG WSG P C CG+PG GK + Y + + C+ + L
Sbjct: 2536 SFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQGK--REGKSFIYQSEVSFSCNFPFIL 2593
Query: 820 EGVIRRMCQENGTWSLEPPICKEIT---CPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCE 876
G R+CQ +GTWS P C E T C +P G T +G + C+
Sbjct: 2594 VGSSTRICQADGTWSGSSPHCIEPTQTSCENPGV---PRHGSQNNTFGFQVGSVVQFHCK 2650
Query: 877 RGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCL 936
+G+ L+G TRTC+ W+G P CIP C+ P + V+ G ++ Y C
Sbjct: 2651 KGHLLQGSTTRTCLPDLTWSGIQPECIPHSCKQPETPAHAN-VVGMDLPSHGYTLIYTCQ 2709
Query: 937 SQYQRV-GPFLRKCLDDGRWSGEEPSCE 963
+ G R C D W+G+ P CE
Sbjct: 2710 PGFFLAGGTEHRVCRSDNTWTGKVPICE 2737
Score = 240 bits (587), Expect = 2e-62
Identities = 152/524 (29%), Positives = 226/524 (43%), Gaps = 49/524 (9%)
Query: 470 WCPDPPAVSNASV-TVNGHKAGSLASYTCENGHILSGSTSVTCTLGG----AWSGVPPSC 524
+C P + + + + G + S+ + C+ G L G +S C AW P+C
Sbjct: 1838 YCSTPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPAC 1897
Query: 525 KYVNCGTPTIHKGSFVLINGTTTY--GSIAQFTCEPDYWLNGAE--ELVCNRDGKWSYD- 579
+ ++CG P +L TT Y G+ + C Y L+ E VC DG WS
Sbjct: 1898 QAISCGIPKAPTNGGIL---TTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHN 1954
Query: 580 -IPSCELTSCPEPE---VPSGGY--MEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGE 633
P C + +CP + G + + Y + + F C+ G+ +G ++ C +G
Sbjct: 1955 KTPRCVVVTCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGT 2014
Query: 634 WS--GDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEE 691
WS + P C+ I CG+LPT P G + T GS ++C + LVG R C
Sbjct: 2015 WSWRNERPYCQIISCGELPTPPNGNK--IGTQTSYGSTAIFTCDLGFMLVGSAVRECLSS 2072
Query: 692 FQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKY 751
WS+S RC C P + IV+ + +G Y V Y
Sbjct: 2073 GLWSESETRCLAGHCGIP----ELIVN-----------------GQVIGENYGYRDTVVY 2111
Query: 752 RCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFY 811
+C G+++IG S+ C+ + WSG P+C V CG+PG G+ + N + +
Sbjct: 2112 QCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGHPGSPIYGRTS--GNGFNFNDVVTF 2169
Query: 812 QCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEA 871
C+ + ++G + CQ N WS PP+CK + C DP + + + G
Sbjct: 2170 SCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVV 2229
Query: 872 HYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSV 931
Y C GY L G C GQW+ +P CI IDC PG N V+S FGS+V
Sbjct: 2230 FYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGHPGVPPNA--VLSGEKYTFGSTV 2287
Query: 932 EYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCE-LATNEAVDSGT 974
Y C + +G R C +G WSG +P C AT D GT
Sbjct: 2288 HYSCTGKRSLLGQSSRTCQLNGHWSGSQPHCSGDATGTCGDPGT 2331
Score = 151 bits (365), Expect = 2e-35
Identities = 147/571 (25%), Positives = 220/571 (38%), Gaps = 52/571 (9%)
Query: 411 CGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTC--GDEGIWDGEAPRCLF 468
C P+ + ++ D+ G Y C FTLVGN TC G+ DG P C
Sbjct: 1665 CQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQV 1724
Query: 469 DWCP-DPPAVSNASVTVN-GHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKY 526
CP + + + V ++ G+ C + ++T + +
Sbjct: 1725 -LCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVLQ 1783
Query: 527 VNCGTPTIHKGSFVLINGTTTYGSIAQFTCE-PDYWLNGAEELVCNRDG-KWSYDIPSCE 584
V G P I S VLI+ + Y S T + +L + + N+ G + Y C
Sbjct: 1784 VYDG-PNIQ--SPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAFYCS 1840
Query: 585 LTSCPEPEVPSGGY-MEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDG----EWSGDSP 639
PE P GY + ++S + + C+ G +L+G+ + VC++ W P
Sbjct: 1841 -----TPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVP 1895
Query: 640 TCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRT--CTEEFQWS-- 695
C+ I CG +P P +L +G+ + Y C YRL T C + WS
Sbjct: 1896 ACQAISCG-IPKAPTNG-GILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNH 1953
Query: 696 DSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEK 755
+ +PRC + C S+ HG I G+ Y V + C+
Sbjct: 1954 NKTPRCVVVTCP----------SINSFILEHGRWRIVN------GSHYEYKTKVVFSCDP 1997
Query: 756 GYKVIGESLSTCEDNGQWS--GTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQC 813
GY +G + C NG WS P CQ + CG NG T YG+TA + C
Sbjct: 1998 GYHGLGPASIECLPNGTWSWRNERPYCQIISCGELPTPPNGNKI--GTQTSYGSTAIFTC 2055
Query: 814 DENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHY 873
D + L G R C +G WS C C P + V+ Y
Sbjct: 2056 DLGFMLVGSAVRECLSSGLWSESETRCLAGHCGIPELIVNG----QVIGENYGYRDTVVY 2111
Query: 874 QCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEY 933
QC G+ L G R C W+G +P C+P+ C PG+ G+ NG F V +
Sbjct: 2112 QCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGHPGSPIYGR-TSGNGFN-FNDVVTF 2169
Query: 934 YCLSQYQRVGPFLRKCLDDGRWSGEEPSCEL 964
C Y GP +C + +WS P C++
Sbjct: 2170 SCNIGYLMQGPTKAQCQANRQWSHPPPMCKV 2200
Score = 126 bits (305), Expect = 3e-28
Identities = 73/241 (30%), Positives = 108/241 (44%), Gaps = 7/241 (2%)
Query: 352 TCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNC 411
TC +P ++ N + G ++D G I Y C G+ L C +G WSG P C C
Sbjct: 2502 TCPTPPQISNGRLEGTNFDWGFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQCLPKFC 2561
Query: 412 GGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDW- 470
G P + + +SC F LVG+ R C +G W G +P C+
Sbjct: 2562 GD--PGIPAQGKREGKSFIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQ 2619
Query: 471 --CPDPPAVSNASVTVN-GHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYV 527
C +P + S G + GS+ + C+ GH+L GST+ TC WSG+ P C
Sbjct: 2620 TSCENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECIPH 2679
Query: 528 NCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWL-NGAEELVCNRDGKWSYDIPSCELT 586
+C P + V+ ++G +TC+P ++L G E VC D W+ +P CE
Sbjct: 2680 SCKQPETPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPICEAG 2739
Query: 587 S 587
S
Sbjct: 2740 S 2740
Score = 58.0 bits (134), Expect = 2e-07
Identities = 47/195 (24%), Positives = 81/195 (41%), Gaps = 23/195 (11%)
Query: 471 CPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGG----AWSGVPPSCKY 526
C DP + N + +K GS +Y C+ G++L G +++TC +G W+ PSC +
Sbjct: 1041 CFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSC-H 1099
Query: 527 VNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELT 586
CG+ T + G++ +Y + V + + +P T
Sbjct: 1100 APCGS-----------RSTGSEGTVLSPNYPKNY--SVGHNCVYSIAVPKEFAVPRTSST 1146
Query: 587 SCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQ----QDGEWSGDSPTCE 642
C P G ++ V S++ F C G+ L G + C+ +W+ PTC
Sbjct: 1147 QCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTC- 1205
Query: 643 YIDCGKLPTLPYGTM 657
+ CG + T GT+
Sbjct: 1206 IVPCGGILTKRKGTI 1220
Score = 57.2 bits (132), Expect = 3e-07
Identities = 28/87 (32%), Positives = 47/87 (54%), Gaps = 1/87 (1%)
Query: 571 NRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQ 630
N K Y+ + SC +P +P G D+ + ST++F C++G++L E L+C++
Sbjct: 333 NNGFKIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEK 392
Query: 631 DGEWSGDSPTCEYIDCGKLPTLPYGTM 657
+ WS PTC+ + CG P GT+
Sbjct: 393 NHWWSHPLPTCDAL-CGGDVRGPSGTI 418
Score = 55.2 bits (127), Expect = 1e-06
Identities = 25/71 (35%), Positives = 38/71 (53%), Gaps = 1/71 (1%)
Query: 587 SCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDC 646
SC +P P G E + + F C+ G +LIGE ++VCQ++ +WS + P C + C
Sbjct: 3 SCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIF-PC 61
Query: 647 GKLPTLPYGTM 657
T P GT+
Sbjct: 62 LSNFTAPMGTV 72
Score = 54.0 bits (124), Expect = 3e-06
Identities = 55/191 (28%), Positives = 79/191 (41%), Gaps = 26/191 (13%)
Query: 349 LPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHC--KKDG--FWSGAPP 404
L +C P ++N T LG DY +GS + Y C G++L G + C DG W+ A P
Sbjct: 1037 LRESCFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALP 1096
Query: 405 SCKYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTL-VGNPERTCGDEGIWDGEA 463
SC + CG + +G V L N + YS N + P+ +
Sbjct: 1097 SC-HAPCGSRSTGSEGTV-LSPNYPKN-----YSVGHNCVYSIAVPK---------EFAV 1140
Query: 464 PRCLFDWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTC-TLGGA---WSG 519
PR C P N GS + C G+IL GS ++ C T+ + W+
Sbjct: 1141 PRTSSTQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWND 1200
Query: 520 VPPSCKYVNCG 530
P+C V CG
Sbjct: 1201 SLPTC-IVPCG 1210
Score = 51.2 bits (117), Expect = 2e-05
Identities = 140/626 (22%), Positives = 220/626 (35%), Gaps = 66/626 (10%)
Query: 352 TCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNC 411
+CG P L G+ + + ++C G L+G+KS C+++ WS P C +
Sbjct: 3 SCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPCL 62
Query: 412 GGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNP-ERTCGDEGIWDGEAPRCLFDW 470
T G V D +G +C +T++ +P R +D E+ FD+
Sbjct: 63 SNFT-APMGTVLSPDYPEGYGNN--LNC--IWTIISDPGSRIHLSFNDFDLESQ---FDF 114
Query: 471 CPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVP-PSCKYVNC 529
S S + + S+ N HIL ++ G + + + C
Sbjct: 115 LAVKDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTFGHNEC 174
Query: 530 GTPTIHKGSFVLINGTTTYGSIAQFTCEPDY-WLNGAEELVC-NRDGK--WSYDIPSCEL 585
P I + GS CE + G E + C DGK WS IP C
Sbjct: 175 PDPGIPINA-RRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKCGA 233
Query: 586 TSCPEPEVPSGGYME-AFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYI 644
PSG + + Y ++N CE + EP + E + +
Sbjct: 234 PCGGHFSAPSGVILSPGWPGYYKDSLN--CE--WVIEAEPGHSIKITFERFQTELNYDVL 289
Query: 645 DCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEI 704
+ P L + NGT + S Y L F+ S
Sbjct: 290 EVHDGPNLLSPLLGSYNGTQVPQFLFSIS-NFIYLLFTTDNSRSNNGFKIHYESVTVNTY 348
Query: 705 RCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESL 764
C DP + + R +GH +G+T V + C+ GY++ E
Sbjct: 349 SCLDP--------GIPVHGRRYGHDF-------SIGST------VSFSCDSGYRLSHEEP 387
Query: 765 STCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIR 824
CE N WS PTC + CG R +G + P FY + C W ++
Sbjct: 388 LLCEKNHWWSHPLPTCDAL-CGGDVRGPSGTILSPGYPEFYPNS--LNC--TWTVDVTHG 442
Query: 825 RMCQEN-GTWSLEPP-----ICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERG 878
+ Q N T+ LE I + + P A++ GS L T++ G +++ +
Sbjct: 443 KGVQFNFHTFHLEDHHDYLLITENGSFTQPLARL-TGSDL---PPTINAGLYGNFRAQLR 498
Query: 879 YNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQ 938
+ + IS +N T C PG + G + N G ++ + C S
Sbjct: 499 F-----ISDFSISYEGFNITFSEYNLEPCEDPGIPQYGSRIGFNFG--IGDTLTFSCSSG 551
Query: 939 YQRVGPFLRKCLDDGR--WSGEEPSC 962
Y+ G CL GR WS P C
Sbjct: 552 YRLEGTSEIICLGGGRRVWSAPLPRC 577
Score = 48.4 bits (110), Expect = 1e-04
Identities = 27/76 (35%), Positives = 37/76 (48%), Gaps = 3/76 (3%)
Query: 584 ELTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQ--DGEWSGDSPTC 641
+L SCP+P G++ D+ V TI+F C G+ LIG L C W+ P C
Sbjct: 1490 QLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRC 1549
Query: 642 EYIDCGKLPTLPYGTM 657
E + CG T GT+
Sbjct: 1550 EAL-CGGNITAMNGTI 1564
Score = 47.6 bits (108), Expect = 2e-04
Identities = 23/57 (40%), Positives = 26/57 (45%), Gaps = 3/57 (5%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
CGHP VPPNA +S E G+ Y C L G R C L G W+ P C
Sbjct: 2265 CGHPGVPPNAVLS---GEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHWSGSQPHC 2318
Score = 46.0 bits (104), Expect = 7e-04
Identities = 22/65 (33%), Positives = 30/65 (46%), Gaps = 3/65 (4%)
Query: 585 LTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQD--GEWSGDSPTCE 642
L SCPEP+ PS G Y V ++F C+ G+ L G ++ C W+ P C
Sbjct: 1319 LDSCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPIC- 1377
Query: 643 YIDCG 647
CG
Sbjct: 1378 LAQCG 1382
Score = 45.6 bits (103), Expect = 0.001
Identities = 21/69 (30%), Positives = 33/69 (47%), Gaps = 3/69 (4%)
Query: 585 LTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGE--WSGDSPTCE 642
L C +P +P G F++ + T+ F C +G++L G ++C G WS P C
Sbjct: 519 LEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRC- 577
Query: 643 YIDCGKLPT 651
+CG T
Sbjct: 578 VAECGASAT 586
Score = 44.8 bits (101), Expect = 0.002
Identities = 107/466 (22%), Positives = 165/466 (35%), Gaps = 57/466 (12%)
Query: 471 CPDPPAVSNASVTVNGHKAGSLASYTCENGHI-LSGSTSVTCTLGGA---WSGVPPSCKY 526
CPDP NA + + GS S CE G I G+ ++TC L WSG+ P C
Sbjct: 174 CPDPGIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKCG- 232
Query: 527 VNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAE-----ELVCNR-DGKWSYDI 580
CG +L G Y CE W+ AE ++ R + +YD+
Sbjct: 233 APCGGHFSAPSGVILSPGWPGYYK-DSLNCE---WVIEAEPGHSIKITFERFQTELNYDV 288
Query: 581 PSCELTSCPEPEVP-SGGYM-EAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDS 638
E+ P P G Y ++ S NF + L N + +S
Sbjct: 289 --LEVHDGPNLLSPLLGSYNGTQVPQFLFSISNFI----YLLFTTDNSRSNNGFKIHYES 342
Query: 639 PTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSS 698
T C P +P + + +GS + +SC + YRL C + WS
Sbjct: 343 VTVNTYSCLD-PGIPVHGRRYGHDFS-IGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPL 400
Query: 699 PRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYK 758
P C+ + C + + G + ++L + DV + G V++ +
Sbjct: 401 PTCDAL-CGGDVRGPSGTILSPGYPEFYPNSL-NCTWTVDVTH----GKGVQFNFHTFHL 454
Query: 759 VIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWE 818
+NG S T P + P I G L N + A + D +
Sbjct: 455 EDHHDYLLITENG--SFTQPLARLTGSDLPPTINAG---LYGN---FRAQLRFISDFSIS 506
Query: 819 LEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERG 878
EG + N LEP C DP + GS + IG + C G
Sbjct: 507 YEGFNITFSEYN----LEP-------CEDPGIP-QYGSR---IGFNFGIGDTLTFSCSSG 551
Query: 879 YNLKGHQTRTCISKGQ--WNGTVPVCIPIDCRSPGNIENGKIVISN 922
Y L+G C+ G+ W+ +P C+ +C + G ++ N
Sbjct: 552 YRLEGTSEIICLGGGRRVWSAPLPRCV-AECGASATNNEGILLSPN 596
Score = 44.8 bits (101), Expect = 0.002
Identities = 57/217 (26%), Positives = 88/217 (40%), Gaps = 37/217 (17%)
Query: 587 SCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVC--QQDGE--WSGDSPTCE 642
SC +P G DY + ST+ ++C+AG+ L G L C DG W+ P+C
Sbjct: 1040 SCFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSC- 1098
Query: 643 YIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCE 702
+ CG T GT +L+ + ++C Y + P +EF + PR
Sbjct: 1099 HAPCGSRSTGSEGT--VLSPNYPKNYSVGHNCV--YSIAVP------KEF----AVPRTS 1144
Query: 703 EIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGE 762
+CS V E GN+ + G +++ D Y + + RCE +
Sbjct: 1145 STQCSS--VPEPRFGRRIGNEFAVGSSVL-----FDCNPGYILHGSIAIRCE----TVPN 1193
Query: 763 SLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLP 799
SL+ QW+ + PTC V CG G + P
Sbjct: 1194 SLA------QWNDSLPTC-IVPCGGILTKRKGTILSP 1223
Score = 44.8 bits (101), Expect = 0.002
Identities = 21/58 (36%), Positives = 27/58 (46%), Gaps = 1/58 (1%)
Query: 2 CGHPAVPPNA-RVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C P +P N+ R S N GT+ Y+C+ GY LFG+ C G W P C
Sbjct: 2203 CSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPEC 2260
Score = 44.4 bits (100), Expect = 0.002
Identities = 54/230 (23%), Positives = 82/230 (35%), Gaps = 15/230 (6%)
Query: 739 VGNTYRIGALVKYRCEKGYKVIGESLSTCED--NGQWSGTTPTCQYVDCGNPGRIENGKV 796
+GN + +G + + C GY +IG S TC + W+ P C+ + CG NG +
Sbjct: 1506 IGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEAL-CGGNITAMNGTI 1564
Query: 797 TLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGS 856
P Y F C W + N T PI IT D Q
Sbjct: 1565 YSPGYPDEY--PNFQDC--FWLVRVPPGNGIYINFTVLQTEPIYDFITVWDGPDQNSPQI 1620
Query: 857 GLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENG 916
G + L E+ Y +K H T + G + + C+ P + N
Sbjct: 1621 GQFSGNTAL----ESVYSTSNQILIKFHSDFT--TSGFFVLSYHAYQLRVCQPPPPVPNA 1674
Query: 917 KIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGR--WSGEEPSCEL 964
+I+ + G + Y CL + VG + C R G P C++
Sbjct: 1675 EILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQV 1724
Score = 43.6 bits (98), Expect = 0.004
Identities = 26/93 (27%), Positives = 43/93 (46%), Gaps = 4/93 (4%)
Query: 333 NDVGCNLDYLHWICQ-YLPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSR 391
+D N H + Q Y +C P N ++GND+ VG I ++C G+ L+G+ +
Sbjct: 1473 SDYSQNKQGFHIVYQAYQLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSAL 1532
Query: 392 HCKK--DGFWSGAPPSCKYVNCGGLTPIEDGDV 422
C W+ P C+ + CGG +G +
Sbjct: 1533 TCLHGVSRNWNHPLPRCEAL-CGGNITAMNGTI 1564
Score = 42.3 bits (95), Expect = 0.009
Identities = 19/62 (30%), Positives = 35/62 (56%), Gaps = 6/62 (9%)
Query: 844 TCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCI--SKGQWNGTVPV 901
+CP+P SG+ + + +G +QC++GY+L+GH TC+ +WN +P+
Sbjct: 1321 SCPEPQTP---SSGIKIGDRYM-VGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPI 1376
Query: 902 CI 903
C+
Sbjct: 1377 CL 1378
Score = 42.3 bits (95), Expect = 0.009
Identities = 20/57 (35%), Positives = 24/57 (42%), Gaps = 3/57 (5%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
CG P P + E N + Y CD GY L G+ +R C G WT P C
Sbjct: 2326 CGDPGTPGHGS---RQESNFRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQPEC 2379
Score = 41.9 bits (94), Expect = 0.012
Identities = 22/59 (37%), Positives = 29/59 (49%), Gaps = 5/59 (8%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGY--ELFGARQRECTLRGDWTLEPPFC 58
CG P +P N + ++ V G Y C GY EL G+R R CT+ G W+ P C
Sbjct: 2443 CGDPGIPANG---LRYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVMPTC 2498
Score = 41.1 bits (92), Expect = 0.021
Identities = 49/223 (21%), Positives = 81/223 (36%), Gaps = 15/223 (6%)
Query: 432 GARALYSCRENFTLVGNPERTC--GDEGIWDGEAPRCLFDWCPDPPAVSNASVTVN-GHK 488
G +SC + L G E C G +W PRC+ + C A +N + ++ +
Sbjct: 541 GDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVAE-C-GASATNNEGILLSPNYP 598
Query: 489 AGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTIHK-GSFVLINGTTT 547
++ C + + + K + T H G+F G +
Sbjct: 599 LNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDGKDKTTHLLGAFT---GASM 655
Query: 548 YGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGY-MEAFDYYV 606
G T WL + +G + S EL+ C +P +P GY + ++
Sbjct: 656 RGLTLSSTSN-QLWLEFNSDTEGTDEG-FQLVYTSFELSHCEDPGIPQFGYKISDQGHFA 713
Query: 607 HSTINFHCEAGHKLIGEPNLVCQ--QDGEWSGDSPTCEYIDCG 647
STI + C G+ L G L C + W P+C +CG
Sbjct: 714 GSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSC-IAECG 755
Score = 41.1 bits (92), Expect = 0.021
Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 9/77 (11%)
Query: 471 CPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGA--WSGVPPSCKYVN 528
CPDP N V N G S+ C G+ L G++++TC G + W+ P C+ +
Sbjct: 1494 CPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEAL- 1552
Query: 529 CGTPTIHKGSFVLINGT 545
CG G+ +NGT
Sbjct: 1553 CG------GNITAMNGT 1563
Score = 41.1 bits (92), Expect = 0.021
Identities = 23/77 (29%), Positives = 35/77 (45%), Gaps = 3/77 (3%)
Query: 1 RCGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGT 60
+CG+P N +V + + +Y C EGY L G R+CT G W+ P C T
Sbjct: 2383 QCGNPGTTANGKVF--RIDGTTFSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNC-T 2439
Query: 61 NVAFRKPANQSTTVRGG 77
++ P + +R G
Sbjct: 2440 IISCGDPGIPANGLRYG 2456
Score = 39.1 bits (87), Expect = 0.085
Identities = 48/229 (20%), Positives = 78/229 (34%), Gaps = 16/229 (6%)
Query: 739 VGNTYRIGALVKYRCEKGYKVIGESLSTCEDN--GQWSGTTPTCQYVDCGNPGRIENGKV 796
+G+ Y +G +V ++C++GY + G S TC +W+ P C CG +G +
Sbjct: 1334 IGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPIC-LAQCGGAMSDFSGVI 1392
Query: 797 TLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGS 856
P Y ++ N + + T ++ + + S I S
Sbjct: 1393 LSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLS 1452
Query: 857 GLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENG 916
G + +S S E Y+ Q C P NG
Sbjct: 1453 GPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQ---------SCPDPRPFRNG 1503
Query: 917 KIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLD--DGRWSGEEPSCE 963
VI N T+ G ++ + C Y +G CL W+ P CE
Sbjct: 1504 -FVIGNDFTV-GQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCE 1550
Score = 38.7 bits (86), Expect = 0.11
Identities = 19/64 (29%), Positives = 30/64 (46%), Gaps = 3/64 (4%)
Query: 469 DWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGA--WSGVPPSCKY 526
D CP+P S+ + + G + S+ C+ G+ L G + +TC G W+ P C
Sbjct: 1320 DSCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPIC-L 1378
Query: 527 VNCG 530
CG
Sbjct: 1379 AQCG 1382
Score = 37.9 bits (84), Expect = 0.20
Identities = 23/82 (28%), Positives = 33/82 (40%), Gaps = 4/82 (4%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTN 61
CGHP P R S N N + + C+ GY + G + +C W+ PP C
Sbjct: 2145 CGHPGSPIYGRTS-GNGFNF--NDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKV- 2200
Query: 62 VAFRKPANQSTTVRGGAAANGN 83
V P + + R +GN
Sbjct: 2201 VNCSDPGIPANSKRESKIEHGN 2222
Score = 37.5 bits (83), Expect = 0.26
Identities = 19/51 (37%), Positives = 26/51 (50%), Gaps = 5/51 (9%)
Query: 867 IGGEAHYQCERGYNLKGHQTRTCI----SKGQWNGTVPVC-IPIDCRSPGN 912
+G Y C+ GY L+G+ T TCI + WN +P C P RS G+
Sbjct: 1059 LGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCGSRSTGS 1109
Score = 36.7 bits (81), Expect = 0.45
Identities = 19/57 (33%), Positives = 27/57 (47%), Gaps = 3/57 (5%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
CG PPN I + + G+ A++ CD G+ L G+ REC G W+ C
Sbjct: 2029 CGELPTPPNGN-KIGTQTSY--GSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRC 2082
Score = 36.3 bits (80), Expect = 0.60
Identities = 20/65 (30%), Positives = 27/65 (41%), Gaps = 4/65 (6%)
Query: 586 TSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGE---WSGDSPTCE 642
T+C +P VP G T+ F C+ G++L GE + C Q W P C
Sbjct: 866 TACRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVC- 924
Query: 643 YIDCG 647
CG
Sbjct: 925 IAPCG 929
Score = 36.3 bits (80), Expect = 0.60
Identities = 24/60 (40%), Positives = 30/60 (50%), Gaps = 6/60 (10%)
Query: 907 CRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCL--DDGR--WSGEEPSC 962
C PGNI NG + + GS+V YYC + Y G C+ DDGR W+ PSC
Sbjct: 1041 CFDPGNIMNGTRLGMDYK--LGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSC 1098
Score = 36.3 bits (80), Expect = 0.60
Identities = 18/62 (29%), Positives = 33/62 (53%), Gaps = 5/62 (8%)
Query: 365 LGNDYDVGSRIVYKCPEGHMLLGDKSRHCK----KDGFWSGAPPSCKYVNCGGLTPIEDG 420
+GN++ VGS +++ C G++L G + C+ W+ + P+C V CGG+ G
Sbjct: 1160 IGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTC-IVPCGGILTKRKG 1218
Query: 421 DV 422
+
Sbjct: 1219 TI 1220
Score = 35.1 bits (77), Expect = 1.4
Identities = 21/60 (35%), Positives = 25/60 (41%), Gaps = 6/60 (10%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTL---RGDWTLEPPFC 58
C P VP N N + G V++CD GYEL G + C R W PP C
Sbjct: 868 CRDPGVPMNGT---RNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVC 924
Score = 35.1 bits (77), Expect = 1.4
Identities = 20/59 (33%), Positives = 27/59 (45%), Gaps = 5/59 (8%)
Query: 785 CGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMC---QENGTWSLEPPIC 840
C +PG NG T + G T +QCD +EL+G R C + W PP+C
Sbjct: 868 CRDPGVPMNG--TRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVC 924
Score = 34.7 bits (76), Expect = 1.8
Identities = 20/74 (27%), Positives = 28/74 (37%), Gaps = 4/74 (5%)
Query: 471 CPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTL---GGAWSGVPPSCKYV 527
C DP N + +G + G + C+ G+ L G +TC W PP C
Sbjct: 868 CRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVC-IA 926
Query: 528 NCGTPTIHKGSFVL 541
CG F+L
Sbjct: 927 PCGGNLTGSSGFIL 940
Score = 34.7 bits (76), Expect = 1.8
Identities = 19/59 (32%), Positives = 25/59 (42%), Gaps = 3/59 (5%)
Query: 528 NCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVC--NRDGKWSYDIPSCE 584
+C P + FV+ N T G F C P Y L G L C W++ +P CE
Sbjct: 1493 SCPDPRPFRNGFVIGNDFTV-GQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCE 1550
Score = 33.5 bits (73), Expect = 4.2
Identities = 24/83 (28%), Positives = 35/83 (42%), Gaps = 4/83 (4%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTN 61
CG P + N +V EN VY+C+ G+ L G+ R C +W+ + P C
Sbjct: 2087 CGIPELIVNGQVI---GENYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSC-VP 2142
Query: 62 VAFRKPANQSTTVRGGAAANGND 84
V+ P + G N ND
Sbjct: 2143 VSCGHPGSPIYGRTSGNGFNFND 2165
Score = 33.1 bits (72), Expect = 5.6
Identities = 15/39 (38%), Positives = 22/39 (56%), Gaps = 3/39 (7%)
Query: 868 GGEAHYQCERGYNLKGHQTRTCI---SKGQWNGTVPVCI 903
G +QC+ GY L+G + TCI ++ W + PVCI
Sbjct: 887 GDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCI 925
Score = 33.1 bits (72), Expect = 5.6
Identities = 20/59 (33%), Positives = 26/59 (44%), Gaps = 4/59 (6%)
Query: 410 NCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTC--GDEGIWDGEAPRC 466
+C P +G V I N T G + C +TL+GN TC G W+ PRC
Sbjct: 1493 SCPDPRPFRNGFV--IGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRC 1549
>AF333704-1|AAK73475.2| 3566|Homo sapiens CUB and sushi multiple
domains 1 protein protein.
Length = 3566
Score = 317 bits (778), Expect = 2e-85
Identities = 198/638 (31%), Positives = 286/638 (44%), Gaps = 49/638 (7%)
Query: 347 QYLPPTCGSPDKLLNTTILGNDYD-VGSRIVYKCPEGHMLLGDKSRHCKKDGF----WSG 401
+Y P C L N IL VGS++ Y C G+ ++G + C+++ W
Sbjct: 2428 RYAAPYCSLTHPLKNGGILNRTAGAVGSKVHYFCKPGYRMVGHSNATCRRNPLGMYQWDS 2487
Query: 402 APPSCKYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERT--CGDEGIW 459
P C+ V+CG P G+ + N T ++ +Y C E F L + + T C ++G+W
Sbjct: 2488 LTPLCQAVSCG--IPESPGNGSFTGNEFTLDSKVVYECHEGFKLESSQQATAVCQEDGLW 2545
Query: 460 D--GEAPRCLFDWCPDPPAVSNASVT---VNG--HKAGSLASYTCENGHILSGSTSVTCT 512
G+ P C CP A + V V+G ++ G+ +C G+ L G + C
Sbjct: 2546 SNKGKPPMCKPVACPSIEAQLSEHVIWRLVSGSLNEYGAQVLLSCSPGYYLEGWRLLRCQ 2605
Query: 513 LGGAWS--GVPPSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVC 570
G W+ PSC+ ++CG+ + I T YG+ A FTC Y L G+ C
Sbjct: 2606 ANGTWNIGDERPSCRVISCGSLSFPPNGNK-IGTLTVYGATAIFTCNTGYTLVGSHVREC 2664
Query: 571 NRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQ 630
+G WS C C P+ G++ + T+ + C G +L+G +C Q
Sbjct: 2665 LANGLWSGSETRCLAGHCGSPDPIVNGHISGDGFSYRDTVVYQCNPGFRLVGTSVRICLQ 2724
Query: 631 DGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTT-HLGSVIQYSCTTNYRLVGPVRRTCT 689
D +WSG +P C I CG +G NG+ +L V+ ++C T Y L G R C
Sbjct: 2725 DHKWSGQTPVCVPITCGHPGNPAHG---FTNGSEFNLNDVVNFTCNTGYLLQGVSRAQCR 2781
Query: 690 EEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALV 749
QWS P C + CSDP E +I HG ++ ++ G +
Sbjct: 2782 SNGQWSSPLPTCRVVNCSDPGFVENAI--------RHGQ--------QNFPESFEYGMSI 2825
Query: 750 KYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATA 809
Y C+KG+ ++G S TC NG W + P C + CG+PG N +T YGA
Sbjct: 2826 LYHCKKGFHLLGSSALTCMANGLWDRSLPKCLAISCGHPGVPANAVLT--GELFTYGAVV 2883
Query: 810 FYQCDENWELEGVIRRMCQENGTWSLEPPICKEIT---CPDPSAQIKAGSGLLVVTSTLS 866
Y C + L G R+CQE+ WS P C C DP GS L T S
Sbjct: 2884 HYSCRGSESLIGNDTRVCQEDSHWSGALPHCTGNNPGFCGDPGTPAH-GSRLGDDFKTKS 2942
Query: 867 IGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTL 926
+ + CE G+ L+G RTC+ G W+G PVC + C +PG NG IV S+G L
Sbjct: 2943 L---LRFSCEMGHQLRGSPERTCLLNGSWSGLQPVCEAVSCGNPGTPTNGMIVSSDG-IL 2998
Query: 927 FGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCEL 964
F SSV Y C Y+ G R C +G W+G P C +
Sbjct: 2999 FSSSVIYACWEGYKTSGLMTRHCTANGTWTGTAPDCTI 3036
Score = 297 bits (730), Expect = 1e-79
Identities = 183/629 (29%), Positives = 281/629 (44%), Gaps = 45/629 (7%)
Query: 349 LPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKY 408
+P TCG P + G+++++ + + C G++L G C+ +G WS P+C+
Sbjct: 2736 VPITCGHPGNPAHGFTNGSEFNLNDVVNFTCNTGYLLQGVSRAQCRSNGQWSSPLPTCRV 2795
Query: 409 VNCGGLTPIEDG---DVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPR 465
VNC +E+ +G LY C++ F L+G+ TC G+WD P+
Sbjct: 2796 VNCSDPGFVENAIRHGQQNFPESFEYGMSILYHCKKGFHLLGSSALTCMANGLWDRSLPK 2855
Query: 466 CLFDWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCK 525
CL C P +NA +T G++ Y+C L G+ + C WSG P C
Sbjct: 2856 CLAISCGHPGVPANAVLTGELFTYGAVVHYSCRGSESLIGNDTRVCQEDSHWSGALPHCT 2915
Query: 526 YVN---CGTP-TIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIP 581
N CG P T GS + + T S+ +F+CE + L G+ E C +G WS P
Sbjct: 2916 GNNPGFCGDPGTPAHGSRLGDDFKTK--SLLRFSCEMGHQLRGSPERTCLLNGSWSGLQP 2973
Query: 582 SCELTSCPEPEVPSGGYMEAFD-YYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPT 640
CE SC P P+ G + + D S++ + C G+K G C +G W+G +P
Sbjct: 2974 VCEAVSCGNPGTPTNGMIVSSDGILFSSSVIYACWEGYKTSGLMTRHCTANGTWTGTAPD 3033
Query: 641 CEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRT--CTEEFQWSDSS 698
C I CG TL G + T + Y C Y + T CT++ +W+ S
Sbjct: 3034 CTIISCGDPGTLANGIQFGTDFT--FNKTVSYQCNPGYVMEAVTSATIRCTKDGRWNPSK 3091
Query: 699 PRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYK 758
P C+ + C P + V G+ +R G+ + Y C GY+
Sbjct: 3092 PVCKAVLCPQPPPVQNGTVE---------------------GSDFRWGSSISYSCMDGYQ 3130
Query: 759 VIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWE 818
+ ++ +CE G W G P C V CG+PG G+ L + Y + F+QC +
Sbjct: 3131 LSHSAILSCEGRGVWKGEIPQCLPVFCGDPGIPAEGR--LSGKSFTYKSEVFFQCKSPFI 3188
Query: 819 LEGVIRRMCQENGTWSLEPPIC---KEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQC 875
L G RR+CQ +GTWS P C TCPDP G+ + +G ++C
Sbjct: 3189 LVGSSRRVCQADGTWSGIQPTCIDPAHNTCPDPGT---PHFGIQNSSRGYEVGSTVFFRC 3245
Query: 876 ERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYC 935
+GY+++G TRTC++ W+G CIP CR P + + + T FG ++ Y C
Sbjct: 3246 RKGYHIQGSTTRTCLANLTWSGIQTECIPHACRQPETPAHADVRAIDLPT-FGYTLVYTC 3304
Query: 936 LSQYQRV-GPFLRKCLDDGRWSGEEPSCE 963
+ G R C D +W+G+ P C+
Sbjct: 3305 HPGFFLAGGSEHRTCKADMKWTGKSPVCK 3333
Score = 283 bits (694), Expect = 2e-75
Identities = 182/623 (29%), Positives = 259/623 (41%), Gaps = 45/623 (7%)
Query: 353 CGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCG 412
CGSPD ++N I G+ + +VY+C G L+G R C +D WSG P C + CG
Sbjct: 2682 CGSPDPIVNGHISGDGFSYRDTVVYQCNPGFRLVGTSVRICLQDHKWSGQTPVCVPITCG 2741
Query: 413 GLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCP 472
P + ++C + L G C G W P C C
Sbjct: 2742 --HPGNPAHGFTNGSEFNLNDVVNFTCNTGYLLQGVSRAQCRSNGQWSSPLPTCRVVNCS 2799
Query: 473 DPPAVSNA-----SVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYV 527
DP V NA + G Y C+ G L GS+++TC G W P C +
Sbjct: 2800 DPGFVENAIRHGQQNFPESFEYGMSILYHCKKGFHLLGSSALTCMANGLWDRSLPKCLAI 2859
Query: 528 NCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTS 587
+CG P + + VL TYG++ ++C L G + VC D WS +P C +
Sbjct: 2860 SCGHPGV-PANAVLTGELFTYGAVVHYSCRGSESLIGNDTRVCQEDSHWSGALPHCTGNN 2918
Query: 588 ---CPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYI 644
C +P P+ G D+ S + F CE GH+L G P C +G WSG P CE +
Sbjct: 2919 PGFCGDPGTPAHGSRLGDDFKTKSLLRFSCEMGHQLRGSPERTCLLNGSWSGLQPVCEAV 2978
Query: 645 DCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEI 704
CG T G + +G SVI Y+C Y+ G + R CT W+ ++P C I
Sbjct: 2979 SCGNPGTPTNGMIVSSDGILFSSSVI-YACWEGYKTSGLMTRHCTANGTWTGTAPDCTII 3037
Query: 705 RCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGY--KVIGE 762
C DP I G + V Y+C GY + +
Sbjct: 3038 SCGDPGTLANGI---------------------QFGTDFTFNKTVSYQCNPGYVMEAVTS 3076
Query: 763 SLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGV 822
+ C +G+W+ + P C+ V C P ++NG T+ + +G++ Y C + ++L
Sbjct: 3077 ATIRCTKDGRWNPSKPVCKAVLCPQPPPVQNG--TVEGSDFRWGSSISYSCMDGYQLSHS 3134
Query: 823 IRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLK 882
C+ G W E P C + C DP I A L + T E +QC+ + L
Sbjct: 3135 AILSCEGRGVWKGEIPQCLPVFCGDPG--IPAEGRLSGKSFTYK--SEVFFQCKSPFILV 3190
Query: 883 GHQTRTCISKGQWNGTVPVCI-PI--DCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQY 939
G R C + G W+G P CI P C PG G S G + GS+V + C Y
Sbjct: 3191 GSSRRVCQADGTWSGIQPTCIDPAHNTCPDPGTPHFGIQNSSRGYEV-GSTVFFRCRKGY 3249
Query: 940 QRVGPFLRKCLDDGRWSGEEPSC 962
G R CL + WSG + C
Sbjct: 3250 HIQGSTTRTCLANLTWSGIQTEC 3272
Score = 166 bits (404), Expect = 3e-40
Identities = 142/545 (26%), Positives = 222/545 (40%), Gaps = 52/545 (9%)
Query: 437 YSCRENFTLVGNPERTC--GDEGIWDGEAPRCLFDWCP--DPPAVSNASVTVNGHKAGSL 492
Y C +TLVG TC + ++G P C CP + S+ + G+
Sbjct: 2286 YQCHPGYTLVGTDILTCKLSSQLQFEGSLPTCEAQ-CPANEVRTGSSGVILSPGYPGNYF 2344
Query: 493 ASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTIHKGSFVLINGTTTYGSIA 552
S TC + + ++T + S V G+ + V+++G T S
Sbjct: 2345 NSQTCSWSIKVEPNYNITIFVDTFQSEKQFDALEVFDGS-SGQSPLLVVLSGNHTEQS-- 2401
Query: 553 QFTCEPD-YWLNGAEELVCNRDG-KWSYDIPSCELTSCPEPEVPSGGYMEAFDYYVHSTI 610
FT + +L + + ++ G K Y P C LT + +GG + V S +
Sbjct: 2402 NFTSRSNQLYLRWSTDHATSKKGFKIRYAAPYCSLTH----PLKNGGILNRTAGAVGSKV 2457
Query: 611 NFHCEAGHKLIGEPNLVCQQDG----EWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHL 666
++ C+ G++++G N C+++ +W +P C+ + CG +P P G L
Sbjct: 2458 HYFCKPGYRMVGHSNATCRRNPLGMYQWDSLTPLCQAVSCG-IPESP-GNGSFTGNEFTL 2515
Query: 667 GSVIQYSCTTNYRLVGPVRRT--CTEEFQWSDSS--PRCEEIRCSDPIVAEKSIVSVTGN 722
S + Y C ++L + T C E+ WS+ P C+ + C I A+ S
Sbjct: 2516 DSKVVYECHEGFKLESSQQATAVCQEDGLWSNKGKPPMCKPVACPS-IEAQLS------- 2567
Query: 723 DRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWS--GTTPTC 780
H + R G+ GA V C GY + G L C+ NG W+ P+C
Sbjct: 2568 ----EHVIWRLVS----GSLNEYGAQVLLSCSPGYYLEGWRLLRCQANGTWNIGDERPSC 2619
Query: 781 QYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPIC 840
+ + CG+ NG T YGATA + C+ + L G R C NG WS C
Sbjct: 2620 RVISCGSLSFPPNGNKI--GTLTVYGATAIFTCNTGYTLVGSHVRECLANGLWSGSETRC 2677
Query: 841 KEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVP 900
C P + + S YQC G+ L G R C+ +W+G P
Sbjct: 2678 LAGHCGSPDPIVNGH----ISGDGFSYRDTVVYQCNPGFRLVGTSVRICLQDHKWSGQTP 2733
Query: 901 VCIPIDCRSPGNIENGKIVISNGSTL-FGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEE 959
VC+PI C PGN +G +NGS V + C + Y G +C +G+WS
Sbjct: 2734 VCVPITCGHPGNPAHG---FTNGSEFNLNDVVNFTCNTGYLLQGVSRAQCRSNGQWSSPL 2790
Query: 960 PSCEL 964
P+C +
Sbjct: 2791 PTCRV 2795
Score = 83.0 bits (196), Expect = 5e-15
Identities = 54/187 (28%), Positives = 80/187 (42%), Gaps = 8/187 (4%)
Query: 345 ICQYLPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPP 404
I Q LP CG P + G + S + ++C +L+G R C+ DG WSG P
Sbjct: 3149 IPQCLPVFCGDPGIPAEGRLSGKSFTYKSEVFFQCKSPFILVGSSRRVCQADGTWSGIQP 3208
Query: 405 SCKYVNCGGLTPIEDGDVAL-IDNRTTH---GARALYSCRENFTLVGNPERTCGDEGIWD 460
+C ++ T + G I N + G+ + CR+ + + G+ RTC W
Sbjct: 3209 TC--IDPAHNTCPDPGTPHFGIQNSSRGYEVGSTVFFRCRKGYHIQGSTTRTCLANLTWS 3266
Query: 461 GEAPRCLFDWCPDPPAVSNASV-TVNGHKAGSLASYTCENGHILS-GSTSVTCTLGGAWS 518
G C+ C P ++A V ++ G YTC G L+ GS TC W+
Sbjct: 3267 GIQTECIPHACRQPETPAHADVRAIDLPTFGYTLVYTCHPGFFLAGGSEHRTCKADMKWT 3326
Query: 519 GVPPSCK 525
G P CK
Sbjct: 3327 GKSPVCK 3333
Score = 58.8 bits (136), Expect = 1e-07
Identities = 64/242 (26%), Positives = 92/242 (38%), Gaps = 18/242 (7%)
Query: 353 CGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHC--KKDG--FWSGAPPSCKY 408
C P ++N T +G D+ +GS I Y+C G+ +L S C DG W PSC
Sbjct: 1565 CFDPGNIMNGTRVGTDFKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLPSCN- 1623
Query: 409 VNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLF 468
CGG +G V L N H A C + T+ E + + A L
Sbjct: 1624 APCGGQYTGSEG-VVLSPN-YPHNYTAGQICLYSITV--PKEFVVFGQFAYFQTALNDLA 1679
Query: 469 DWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGG---AWSGVPPSCK 525
+ A + +++G +G N +L S + G + VP +
Sbjct: 1680 ELFDGTHAQARLLSSLSGSHSGETLPLATSNQILLRFSAKSGASARGFHFVYQAVPRTSD 1739
Query: 526 YVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVC----NRDGKWSYDIP 581
P G I + GSI +F C P Y L G+ L C N +W+ IP
Sbjct: 1740 TQCSSVPEPRYGR--RIGSEFSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQWNDTIP 1797
Query: 582 SC 583
SC
Sbjct: 1798 SC 1799
Score = 56.0 bits (129), Expect = 7e-07
Identities = 22/70 (31%), Positives = 41/70 (58%), Gaps = 1/70 (1%)
Query: 578 YDIPSCELTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGD 637
Y+ + E SC +P +P G+ D+ + ST+ F C+ G+ L + LVC+++ +W+
Sbjct: 864 YESVTLESDSCLDPGIPVNGHRHGGDFGIRSTVTFSCDPGYTLSDDEPLVCERNHQWNHA 923
Query: 638 SPTCEYIDCG 647
P+C+ + CG
Sbjct: 924 LPSCDAL-CG 932
Score = 55.6 bits (128), Expect = 9e-07
Identities = 34/90 (37%), Positives = 46/90 (51%), Gaps = 6/90 (6%)
Query: 571 NRDG-KWSYDIPSCELTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQ 629
NR G K +Y + EL +CP+P GYM DY V +++F C G+ LIG P L CQ
Sbjct: 2073 NRQGFKLAYQ--AYELQNCPDPPPFQNGYMINSDYSVGQSVSFECYPGYILIGHPVLTCQ 2130
Query: 630 Q--DGEWSGDSPTCEYIDCGKLPTLPYGTM 657
+ W+ P C+ CG T GT+
Sbjct: 2131 HGINRNWNYPFPRCD-APCGYNVTSQNGTI 2159
Score = 53.2 bits (122), Expect = 5e-06
Identities = 20/60 (33%), Positives = 33/60 (55%)
Query: 584 ELTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEY 643
E C +P +P+ G + T+ F C A +L+GE + CQQ+ +WSG+ P+C +
Sbjct: 524 EKGGCGDPGIPAYGKRTGSSFLHGDTLTFECPAAFELVGERVITCQQNNQWSGNKPSCVF 583
Score = 47.6 bits (108), Expect = 2e-04
Identities = 24/76 (31%), Positives = 36/76 (47%), Gaps = 3/76 (3%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTN 61
CG+P P N I + + I+ + +Y C EGY+ G R CT G WT P C T
Sbjct: 2980 CGNPGTPTNGM--IVSSDGILFSSSVIYACWEGYKTSGLMTRHCTANGTWTGTAPDC-TI 3036
Query: 62 VAFRKPANQSTTVRGG 77
++ P + ++ G
Sbjct: 3037 ISCGDPGTLANGIQFG 3052
Score = 46.0 bits (104), Expect = 7e-04
Identities = 19/67 (28%), Positives = 35/67 (52%), Gaps = 1/67 (1%)
Query: 740 GNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLP 799
G+++ G + + C ++++GE + TC+ N QWSG P+C + C +G + P
Sbjct: 541 GSSFLHGDTLTFECPAAFELVGERVITCQQNNQWSGNKPSCVF-SCFFNFTASSGIILSP 599
Query: 800 SNATFYG 806
+ YG
Sbjct: 600 NYPEEYG 606
Score = 43.2 bits (97), Expect = 0.005
Identities = 67/291 (23%), Positives = 114/291 (39%), Gaps = 42/291 (14%)
Query: 650 PTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTC---TEEF-QWSDSSPRCEEIR 705
P +P + + +G+ +Q+SC NY L G TC TE WSD P C
Sbjct: 352 PGIPENGRRAGSDFSRVGANVQFSCEDNYVLQGSKSITCQRVTETLAAWSDHRPICRART 411
Query: 706 CSDPIVAEKSIVS-----VTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVI 760
C + +++ V D +H +I T+D V A ++ E+GY +
Sbjct: 412 CGSNLRGPSGVITSPNYPVQYEDNAHCVWVITTTDPDKVIKL----AFEEFELERGYDTL 467
Query: 761 GESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELE 820
T D G+ G T + YV G+ + + V++ + + Q D++
Sbjct: 468 -----TVGDAGK-VGDTRSVLYVLTGS--SVPDLIVSMSNQMWLH-----LQSDDSIGSP 514
Query: 821 GVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYN 880
G + + QE +E C + P+ + GS L G ++C +
Sbjct: 515 G-FKAVYQE-----IEKGGCGDPGI--PAYGKRTGSSFL-------HGDTLTFECPAAFE 559
Query: 881 LKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSV 931
L G + TC QW+G P C+ C +G I+ N +G+++
Sbjct: 560 LVGERVITCQQNNQWSGNKPSCV-FSCFFNFTASSGIILSPNYPEEYGNNM 609
Score = 43.2 bits (97), Expect = 0.005
Identities = 23/70 (32%), Positives = 32/70 (45%), Gaps = 2/70 (2%)
Query: 585 LTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQD--GEWSGDSPTCE 642
L +C EP +PS Y V+ ++F CE G+ L G ++ C W+ SP C
Sbjct: 1914 LAACQEPALPSNSIKIGDRYMVNDVLSFQCEPGYTLQGRSHISCMPGTVRRWNYPSPLCI 1973
Query: 643 YIDCGKLPTL 652
G L TL
Sbjct: 1974 ATCGGTLSTL 1983
Score = 42.3 bits (95), Expect = 0.009
Identities = 15/35 (42%), Positives = 24/35 (68%)
Query: 550 SIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCE 584
S F+C+P Y L+ E LVC R+ +W++ +PSC+
Sbjct: 894 STVTFSCDPGYTLSDDEPLVCERNHQWNHALPSCD 928
Score = 41.9 bits (94), Expect = 0.012
Identities = 29/120 (24%), Positives = 48/120 (40%), Gaps = 8/120 (6%)
Query: 297 VDGELVSKPSWGKDQPNNYNGEQNCVVLDGGRGWLWNDVGCNLDYLHWICQYLPPTCGSP 356
VD +++ K G P + + N + L + + G ++ + I TC P
Sbjct: 1340 VDSDILLKEWSGSALPEDIHSTFNSLTLQFDSDFFISKSGFSIQFSTSIAA----TCNDP 1395
Query: 357 DKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDG---FWSGAPPSCKYVNCGG 413
N T G+ + G + ++C G+ L G C + FW PP+C CGG
Sbjct: 1396 GMPQNGTRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTC-IAACGG 1454
Score = 41.5 bits (93), Expect = 0.016
Identities = 21/71 (29%), Positives = 35/71 (49%), Gaps = 1/71 (1%)
Query: 352 TCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNC 411
+C P +N G D+ + S + + C G+ L D+ C+++ W+ A PSC + C
Sbjct: 873 SCLDPGIPVNGHRHGGDFGIRSTVTFSCDPGYTLSDDEPLVCERNHQWNHALPSCDAL-C 931
Query: 412 GGLTPIEDGDV 422
GG + G V
Sbjct: 932 GGYIQGKSGTV 942
Score = 41.5 bits (93), Expect = 0.016
Identities = 20/66 (30%), Positives = 32/66 (48%), Gaps = 1/66 (1%)
Query: 740 GNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLP 799
G + I + V + C+ GY + + CE N QW+ P+C + CG + ++G V P
Sbjct: 887 GGDFGIRSTVTFSCDPGYTLSDDEPLVCERNHQWNHALPSCDAL-CGGYIQGKSGTVLSP 945
Query: 800 SNATFY 805
FY
Sbjct: 946 GFPDFY 951
Score = 41.5 bits (93), Expect = 0.016
Identities = 21/73 (28%), Positives = 33/73 (45%), Gaps = 5/73 (6%)
Query: 739 VGNTYRIGALVKYRCEKGYKVIGESLSTC----EDNGQWSGTTPTCQYVDCGNPGRIENG 794
VG +++G+ + Y+C+ GYK++ S TC + W P+C CG G
Sbjct: 1577 VGTDFKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLPSCN-APCGGQYTGSEG 1635
Query: 795 KVTLPSNATFYGA 807
V P+ Y A
Sbjct: 1636 VVLSPNYPHNYTA 1648
Score = 41.1 bits (92), Expect = 0.021
Identities = 24/90 (26%), Positives = 38/90 (42%), Gaps = 6/90 (6%)
Query: 330 WLWNDVGCNLDYLHWICQYLPP-TCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGD 388
W D + + + LP TCG+P ++L + G +++G +I Y C G++L G
Sbjct: 121 WFTTDFAVSAQGFKALYEVLPSHTCGNPGEILKGVLHGTRFNIGDKIRYSCLPGYILEGH 180
Query: 389 KSRHC----KKDGFWSGAPPSCKYVN-CGG 413
C W P C+ CGG
Sbjct: 181 AILTCIVSPGNGASWDFPAPFCRAEGACGG 210
Score = 40.7 bits (91), Expect = 0.028
Identities = 22/74 (29%), Positives = 32/74 (43%), Gaps = 4/74 (5%)
Query: 587 SCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGE---WSGDSPTCEY 643
+C +P +P G T+ F C+ G++L G+ + C Q W D PTC
Sbjct: 1391 TCNDPGMPQNGTRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTC-I 1449
Query: 644 IDCGKLPTLPYGTM 657
CG T P G +
Sbjct: 1450 AACGGNLTGPAGVI 1463
Score = 40.7 bits (91), Expect = 0.028
Identities = 16/41 (39%), Positives = 26/41 (63%), Gaps = 2/41 (4%)
Query: 743 YRIGALVKYRCEKGYKVIGESLSTCEDNG--QWSGTTPTCQ 781
+ IG VKY+C GY ++G + TC+ + Q+ G+ PTC+
Sbjct: 2278 FEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPTCE 2318
Score = 39.9 bits (89), Expect = 0.049
Identities = 21/66 (31%), Positives = 30/66 (45%), Gaps = 3/66 (4%)
Query: 584 ELTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGE--WSGDSPTC 641
+L C +P VP+ F + V ++ F C G++L G L C G WS P C
Sbjct: 1042 DLEPCDDPGVPAFSRRIGFHFGVGDSLTFSCFLGYRLEGATKLTCLGGGRRVWSAPLPRC 1101
Query: 642 EYIDCG 647
+CG
Sbjct: 1102 -VAECG 1106
Score = 39.1 bits (87), Expect = 0.085
Identities = 16/56 (28%), Positives = 28/56 (50%)
Query: 353 CGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKY 408
CG P G+ + G + ++CP L+G++ C+++ WSG PSC +
Sbjct: 528 CGDPGIPAYGKRTGSSFLHGDTLTFECPAAFELVGERVITCQQNNQWSGNKPSCVF 583
Score = 39.1 bits (87), Expect = 0.085
Identities = 21/62 (33%), Positives = 28/62 (45%), Gaps = 3/62 (4%)
Query: 471 CPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLG--GAWSGVPPSCKYVN 528
CPDPP N + + + G S+ C G+IL G +TC G W+ P C
Sbjct: 2089 CPDPPPFQNGYMINSDYSVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYPFPRCD-AP 2147
Query: 529 CG 530
CG
Sbjct: 2148 CG 2149
Score = 38.7 bits (86), Expect = 0.11
Identities = 22/75 (29%), Positives = 32/75 (42%), Gaps = 5/75 (6%)
Query: 588 CPEPEVPSGGYMEAFDYY-VHSTINFHCEAGHKLIGEPNLVCQQDGE----WSGDSPTCE 642
C +P +P G D+ V + + F CE + L G ++ CQ+ E WS P C
Sbjct: 349 CLDPGIPENGRRAGSDFSRVGANVQFSCEDNYVLQGSKSITCQRVTETLAAWSDHRPICR 408
Query: 643 YIDCGKLPTLPYGTM 657
CG P G +
Sbjct: 409 ARTCGSNLRGPSGVI 423
Score = 38.7 bits (86), Expect = 0.11
Identities = 23/79 (29%), Positives = 41/79 (51%), Gaps = 8/79 (10%)
Query: 785 CGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEG----VIRRMCQENGTWSLEPPIC 840
C +PG ENG+ S+ + GA + C++N+ L+G +R+ + WS PIC
Sbjct: 349 CLDPGIPENGR-RAGSDFSRVGANVQFSCEDNYVLQGSKSITCQRVTETLAAWSDHRPIC 407
Query: 841 KEITCPDPSAQIKAGSGLL 859
+ TC + ++ SG++
Sbjct: 408 RARTC---GSNLRGPSGVI 423
Score = 38.7 bits (86), Expect = 0.11
Identities = 20/74 (27%), Positives = 33/74 (44%), Gaps = 5/74 (6%)
Query: 737 RDVGNTYRIGALVKYRCEKGYKVIGESLSTCED----NGQWSGTTPTCQYVDCGNPGRIE 792
R +G+ + G++V++ C GY + G + C+ QW+ T P+C V C
Sbjct: 1752 RRIGSEFSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQWNDTIPSC-VVPCSGNFTQR 1810
Query: 793 NGKVTLPSNATFYG 806
G + P YG
Sbjct: 1811 RGTILSPGYPEPYG 1824
Score = 38.7 bits (86), Expect = 0.11
Identities = 19/63 (30%), Positives = 29/63 (46%), Gaps = 3/63 (4%)
Query: 739 VGNTYRIGALVKYRCEKGYKVIGESLSTCED--NGQWSGTTPTCQYVDCGNPGRIENGKV 796
+ + Y +G V + C GY +IG + TC+ N W+ P C CG +NG +
Sbjct: 2101 INSDYSVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYPFPRCD-APCGYNVTSQNGTI 2159
Query: 797 TLP 799
P
Sbjct: 2160 YSP 2162
Score = 37.9 bits (84), Expect = 0.20
Identities = 22/67 (32%), Positives = 33/67 (49%), Gaps = 7/67 (10%)
Query: 471 CPDPPAVSNASVTVNGH-KAGSLASYTCENGHILSGSTSVTC-----TLGGAWSGVPPSC 524
C DP N + + G+ ++CE+ ++L GS S+TC TL AWS P C
Sbjct: 349 CLDPGIPENGRRAGSDFSRVGANVQFSCEDNYVLQGSKSITCQRVTETL-AAWSDHRPIC 407
Query: 525 KYVNCGT 531
+ CG+
Sbjct: 408 RARTCGS 414
Score = 37.9 bits (84), Expect = 0.20
Identities = 21/70 (30%), Positives = 31/70 (44%), Gaps = 4/70 (5%)
Query: 549 GSIAQFTCEPDYWLNGAEELVCNRD----GKWSYDIPSCELTSCPEPEVPSGGYMEAFDY 604
G+ QF+CE +Y L G++ + C R WS P C +C G + + +Y
Sbjct: 369 GANVQFSCEDNYVLQGSKSITCQRVTETLAAWSDHRPICRARTCGSNLRGPSGVITSPNY 428
Query: 605 YVHSTINFHC 614
V N HC
Sbjct: 429 PVQYEDNAHC 438
Score = 37.5 bits (83), Expect = 0.26
Identities = 18/56 (32%), Positives = 29/56 (51%), Gaps = 2/56 (3%)
Query: 907 CRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
C PG GK + S L G ++ + C + ++ VG + C + +WSG +PSC
Sbjct: 528 CGDPGIPAYGKR--TGSSFLHGDTLTFECPAAFELVGERVITCQQNNQWSGNKPSC 581
Score = 37.5 bits (83), Expect = 0.26
Identities = 22/64 (34%), Positives = 25/64 (39%), Gaps = 4/64 (6%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC-GT 60
CGHP VP NA + E G + Y C L G R C W+ P C G
Sbjct: 2861 CGHPGVPANA---VLTGELFTYGAVVHYSCRGSESLIGNDTRVCQEDSHWSGALPHCTGN 2917
Query: 61 NVAF 64
N F
Sbjct: 2918 NPGF 2921
Score = 36.7 bits (81), Expect = 0.45
Identities = 23/86 (26%), Positives = 40/86 (46%), Gaps = 9/86 (10%)
Query: 336 GCNLDYLHWICQYLPPT----CGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSR 391
G + H++ Q +P T C S + +G+++ GS + ++C G++L G +
Sbjct: 1721 GASARGFHFVYQAVPRTSDTQCSSVPEPRYGRRIGSEFSAGSIVRFECNPGYLLQGSTAL 1780
Query: 392 HCKKD----GFWSGAPPSCKYVNCGG 413
HC+ W+ PSC V C G
Sbjct: 1781 HCQSVPNALAQWNDTIPSC-VVPCSG 1805
Score = 36.7 bits (81), Expect = 0.45
Identities = 51/238 (21%), Positives = 83/238 (34%), Gaps = 15/238 (6%)
Query: 471 CPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGA--WSGVPPSCKYVN 528
C +P SN+ + + + S+ CE G+ L G + ++C G W+ P C
Sbjct: 1917 CQEPALPSNSIKIGDRYMVNDVLSFQCEPGYTLQGRSHISCMPGTVRRWNYPSPLC-IAT 1975
Query: 529 CGTPTIHKGSFVLING-TTTYGSIAQFTCEPDYWLN-GAEELVCNRDGKWSYDIPSCELT 586
CG G +L G +Y + T + GA N + ++D E+
Sbjct: 1976 CGGTLSTLGGVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTEANHDF--LEIQ 2033
Query: 587 SCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDC 646
+ P P G D H LI + Q + E +C
Sbjct: 2034 NGPYHTSPMIGQFSGTDLPAALLSTTH----ETLIHFYSDHSQNRQGFKLAYQAYELQNC 2089
Query: 647 GKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEF--QWSDSSPRCE 702
P P+ ++N +G + + C Y L+G TC W+ PRC+
Sbjct: 2090 PDPP--PFQNGYMINSDYSVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYPFPRCD 2145
Score = 36.7 bits (81), Expect = 0.45
Identities = 19/63 (30%), Positives = 30/63 (47%), Gaps = 4/63 (6%)
Query: 584 ELTSC-PEPEVPSGGYM-EAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDG--EWSGDSP 639
+L C P P VP + E D+ + + + C G+ L+G L C+ ++ G P
Sbjct: 2256 QLKKCQPPPAVPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLP 2315
Query: 640 TCE 642
TCE
Sbjct: 2316 TCE 2318
Score = 36.7 bits (81), Expect = 0.45
Identities = 18/51 (35%), Positives = 24/51 (47%), Gaps = 3/51 (5%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWT 52
CG + PPN V G A++ C+ GY L G+ REC G W+
Sbjct: 2624 CGSLSFPPNGNKI---GTLTVYGATAIFTCNTGYTLVGSHVRECLANGLWS 2671
Score = 36.3 bits (80), Expect = 0.60
Identities = 20/59 (33%), Positives = 30/59 (50%), Gaps = 5/59 (8%)
Query: 785 CGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMC-QENGT--WSLEPPIC 840
C +PG +NG T ++ G T +QCD ++L+G + C Q N W +PP C
Sbjct: 1392 CNDPGMPQNG--TRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTC 1448
Score = 35.9 bits (79), Expect = 0.79
Identities = 23/87 (26%), Positives = 40/87 (45%), Gaps = 5/87 (5%)
Query: 736 NRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQ--WSGTTPTCQYVDCGNPGRIEN 793
+R +G + +G + + C GY++ G + TC G+ WS P C +CG +
Sbjct: 1055 SRRIGFHFGVGDSLTFSCFLGYRLEGATKLTCLGGGRRVWSAPLPRC-VAECGASVKGNE 1113
Query: 794 GKVTLPSNATFYGATAFYQCDENWELE 820
G + P+ + Y T ++C E E
Sbjct: 1114 GTLLSPNFPSNYDNT--HECIYKIETE 1138
Score = 35.9 bits (79), Expect = 0.79
Identities = 20/64 (31%), Positives = 29/64 (45%), Gaps = 6/64 (9%)
Query: 471 CPDPPAVSNASVTVN--GHKAGSLASYTCENGHILSGSTSVTCTLGG--AWSGVPPSCKY 526
C DP + N + GH ++ Y+C G+ + GS ++TC G W PSC
Sbjct: 1218 CEDP-GIPNYGYRIRDEGHFTDTVVLYSCNPGYAMHGSNTLTCLSGDRRVWDKPLPSC-I 1275
Query: 527 VNCG 530
CG
Sbjct: 1276 AECG 1279
Score = 35.9 bits (79), Expect = 0.79
Identities = 19/63 (30%), Positives = 28/63 (44%), Gaps = 4/63 (6%)
Query: 471 CPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCT-LGGA--WSGVPPSCKYV 527
C DP N + + +AG ++ C+ G+ L G +TC L W PP+C
Sbjct: 1392 CNDPGMPQNGTRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTC-IA 1450
Query: 528 NCG 530
CG
Sbjct: 1451 ACG 1453
Score = 35.9 bits (79), Expect = 0.79
Identities = 21/72 (29%), Positives = 31/72 (43%), Gaps = 5/72 (6%)
Query: 471 CPDPPAVSNASVTV--NGHKAGSLASYTCENGHILSGSTSVTCTLGG--AWSGVPPSCKY 526
C PPAV A + + + G Y C G+ L G+ +TC L + G P+C+
Sbjct: 2260 CQPPPAVPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPTCE- 2318
Query: 527 VNCGTPTIHKGS 538
C + GS
Sbjct: 2319 AQCPANEVRTGS 2330
Score = 35.5 bits (78), Expect = 1.0
Identities = 17/67 (25%), Positives = 30/67 (44%), Gaps = 3/67 (4%)
Query: 532 PTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYD--IPSCELTSCP 589
P + + + + G ++ C P Y L G + L C + ++ +P+CE CP
Sbjct: 2264 PAVPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPTCE-AQCP 2322
Query: 590 EPEVPSG 596
EV +G
Sbjct: 2323 ANEVRTG 2329
Score = 35.5 bits (78), Expect = 1.0
Identities = 16/57 (28%), Positives = 23/57 (40%), Gaps = 3/57 (5%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
CGHP P + N + + C+ GY L G + +C G W+ P C
Sbjct: 2740 CGHPGNPAHG---FTNGSEFNLNDVVNFTCNTGYLLQGVSRAQCRSNGQWSSPLPTC 2793
Score = 35.1 bits (77), Expect = 1.4
Identities = 21/80 (26%), Positives = 29/80 (36%)
Query: 471 CPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCG 530
C DP + T + G ++ C L G +TC WSG PSC +
Sbjct: 528 CGDPGIPAYGKRTGSSFLHGDTLTFECPAAFELVGERVITCQQNNQWSGNKPSCVFSCFF 587
Query: 531 TPTIHKGSFVLINGTTTYGS 550
T G + N YG+
Sbjct: 588 NFTASSGIILSPNYPEEYGN 607
Score = 35.1 bits (77), Expect = 1.4
Identities = 22/96 (22%), Positives = 35/96 (36%), Gaps = 7/96 (7%)
Query: 639 PTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEE----FQW 694
P C +P YG + GS++++ C Y L G C QW
Sbjct: 1735 PRTSDTQCSSVPEPRYGRR--IGSEFSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQW 1792
Query: 695 SDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTL 730
+D+ P C + CS + + G +G+ L
Sbjct: 1793 NDTIPSC-VVPCSGNFTQRRGTILSPGYPEPYGNNL 1827
Score = 35.1 bits (77), Expect = 1.4
Identities = 18/59 (30%), Positives = 26/59 (44%), Gaps = 2/59 (3%)
Query: 646 CGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTC--TEEFQWSDSSPRCE 702
C P +P M + +G ++Y C Y LVG TC + + Q+ S P CE
Sbjct: 2260 CQPPPAVPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPTCE 2318
Score = 34.7 bits (76), Expect = 1.8
Identities = 24/63 (38%), Positives = 31/63 (49%), Gaps = 8/63 (12%)
Query: 844 TCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCI-SKG---QWNGTV 899
TC +P +K G+L T +IG + Y C GY L+GH TCI S G W+
Sbjct: 144 TCGNPGEILK---GVLHGTR-FNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFPA 199
Query: 900 PVC 902
P C
Sbjct: 200 PFC 202
Score = 34.7 bits (76), Expect = 1.8
Identities = 25/82 (30%), Positives = 35/82 (42%), Gaps = 13/82 (15%)
Query: 469 DWCPDPPAVSNASVTVNGHKAG------SLASYTCENGHILSGSTSVTCTLGGAWSGVPP 522
D C DP + VNGH+ G S +++C+ G+ LS + C W+ P
Sbjct: 872 DSCLDP------GIPVNGHRHGGDFGIRSTVTFSCDPGYTLSDDEPLVCERNHQWNHALP 925
Query: 523 SCKYVNCGTPTIHKGSFVLING 544
SC + CG K VL G
Sbjct: 926 SCDAL-CGGYIQGKSGTVLSPG 946
Score = 34.7 bits (76), Expect = 1.8
Identities = 17/69 (24%), Positives = 31/69 (44%), Gaps = 4/69 (5%)
Query: 582 SCELTSCPEPEVPSGGY-MEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGE--WSGDS 638
S +L C +P +P+ GY + ++ + + + C G+ + G L C W
Sbjct: 1212 SFDLVKCEDPGIPNYGYRIRDEGHFTDTVVLYSCNPGYAMHGSNTLTCLSGDRRVWDKPL 1271
Query: 639 PTCEYIDCG 647
P+C +CG
Sbjct: 1272 PSC-IAECG 1279
Score = 34.7 bits (76), Expect = 1.8
Identities = 20/75 (26%), Positives = 32/75 (42%), Gaps = 5/75 (6%)
Query: 861 VTSTLSIGGEAHYQCERGYNLKGHQTRTCIS----KGQWNGTVPVCIPIDCRSPGNIENG 916
+ S S G ++C GY L+G C S QWN T+P C+ + C G
Sbjct: 1754 IGSEFSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQWNDTIPSCV-VPCSGNFTQRRG 1812
Query: 917 KIVISNGSTLFGSSV 931
I+ +G+++
Sbjct: 1813 TILSPGYPEPYGNNL 1827
Score = 34.7 bits (76), Expect = 1.8
Identities = 20/66 (30%), Positives = 33/66 (50%), Gaps = 4/66 (6%)
Query: 489 AGSLASYTCENGHILSGSTSVTC-TLGGA---WSGVPPSCKYVNCGTPTIHKGSFVLING 544
AGS+ + C G++L GST++ C ++ A W+ PSC G T +G+ +
Sbjct: 1760 AGSIVRFECNPGYLLQGSTALHCQSVPNALAQWNDTIPSCVVPCSGNFTQRRGTILSPGY 1819
Query: 545 TTTYGS 550
YG+
Sbjct: 1820 PEPYGN 1825
Score = 34.7 bits (76), Expect = 1.8
Identities = 22/83 (26%), Positives = 32/83 (38%), Gaps = 4/83 (4%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTN 61
CG P N +S + VY+C+ G+ L G R C W+ + P C
Sbjct: 2682 CGSPDPIVNGHIS---GDGFSYRDTVVYQCNPGFRLVGTSVRICLQDHKWSGQTPVC-VP 2737
Query: 62 VAFRKPANQSTTVRGGAAANGND 84
+ P N + G+ N ND
Sbjct: 2738 ITCGHPGNPAHGFTNGSEFNLND 2760
Score = 34.7 bits (76), Expect = 1.8
Identities = 16/58 (27%), Positives = 30/58 (51%), Gaps = 5/58 (8%)
Query: 2 CGHPAVPPN-ARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
CG P P + +R+ ++ ++ + C+ G++L G+ +R C L G W+ P C
Sbjct: 2922 CGDPGTPAHGSRLG----DDFKTKSLLRFSCEMGHQLRGSPERTCLLNGSWSGLQPVC 2975
Score = 34.3 bits (75), Expect = 2.4
Identities = 14/38 (36%), Positives = 16/38 (42%)
Query: 431 HGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLF 468
HG + C F LVG TC W G P C+F
Sbjct: 546 HGDTLTFECPAAFELVGERVITCQQNNQWSGNKPSCVF 583
Score = 34.3 bits (75), Expect = 2.4
Identities = 21/61 (34%), Positives = 28/61 (45%), Gaps = 4/61 (6%)
Query: 473 DPPAVSNASVTVNGH-KAGSLASYTCENGHILSGSTSVTCTLGG--AWSGVPPSCKYVNC 529
D P V S + H G +++C G+ L G+T +TC GG WS P C C
Sbjct: 1047 DDPGVPAFSRRIGFHFGVGDSLTFSCFLGYRLEGATKLTCLGGGRRVWSAPLPRC-VAEC 1105
Query: 530 G 530
G
Sbjct: 1106 G 1106
Score = 34.3 bits (75), Expect = 2.4
Identities = 18/72 (25%), Positives = 33/72 (45%), Gaps = 3/72 (4%)
Query: 353 CGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKK--DGFWSGAPPSCKYVN 410
C P N ++ +DY VG + ++C G++L+G C+ + W+ P C
Sbjct: 2089 CPDPPPFQNGYMINSDYSVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYPFPRCD-AP 2147
Query: 411 CGGLTPIEDGDV 422
CG ++G +
Sbjct: 2148 CGYNVTSQNGTI 2159
Score = 34.3 bits (75), Expect = 2.4
Identities = 26/84 (30%), Positives = 38/84 (45%), Gaps = 10/84 (11%)
Query: 845 CPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTC--ISKGQWNGTVPVC 902
C P A +A +L IG YQC GY L G TC S+ Q+ G++P C
Sbjct: 2260 CQPPPAVPQAE--MLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPTC 2317
Query: 903 IPIDCRSPGN-IENGK--IVISNG 923
+ + P N + G +++S G
Sbjct: 2318 ---EAQCPANEVRTGSSGVILSPG 2338
Score = 33.9 bits (74), Expect = 3.2
Identities = 24/87 (27%), Positives = 36/87 (41%), Gaps = 7/87 (8%)
Query: 646 CGKLPTLP-YGTMELLNGTTHL-GSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEE 703
CG P +P YG G++ L G + + C + LVG TC + QWS + P C
Sbjct: 528 CGD-PGIPAYGKR---TGSSFLHGDTLTFECPAAFELVGERVITCQQNNQWSGNKPSC-V 582
Query: 704 IRCSDPIVAEKSIVSVTGNDRSHGHTL 730
C A I+ +G+ +
Sbjct: 583 FSCFFNFTASSGIILSPNYPEEYGNNM 609
Score = 33.9 bits (74), Expect = 3.2
Identities = 24/76 (31%), Positives = 31/76 (40%), Gaps = 7/76 (9%)
Query: 845 CPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCIS--KGQWNGTVPVC 902
CPDP + G ++ S S+G ++C GY L GH TC WN P C
Sbjct: 2089 CPDPPP-FQNG---YMINSDYSVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYPFPRC 2144
Query: 903 IPIDCRSPGNIENGKI 918
C +NG I
Sbjct: 2145 -DAPCGYNVTSQNGTI 2159
Score = 33.5 bits (73), Expect = 4.2
Identities = 22/73 (30%), Positives = 36/73 (49%), Gaps = 10/73 (13%)
Query: 717 VSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTC-EDNGQ--W 773
++ T ND R D+R+ G+T V ++C+ GY++ G++ TC + N + W
Sbjct: 1388 IAATCNDPGMPQNGTRYGDSREAGDT------VTFQCDPGYQLQGQAKITCVQLNNRFFW 1441
Query: 774 SGTTPTCQYVDCG 786
PTC CG
Sbjct: 1442 QPDPPTC-IAACG 1453
Score = 33.5 bits (73), Expect = 4.2
Identities = 19/60 (31%), Positives = 26/60 (43%), Gaps = 6/60 (10%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTL---RGDWTLEPPFC 58
C P +P N + E AG ++CD GY+L G + C R W +PP C
Sbjct: 1392 CNDPGMPQNGTRYGDSRE---AGDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTC 1448
Score = 33.1 bits (72), Expect = 5.6
Identities = 19/65 (29%), Positives = 30/65 (46%), Gaps = 5/65 (7%)
Query: 353 CGSPDKLLNTTILGNDYD-VGSRIVYKCPEGHMLLGDKSRHCKKD----GFWSGAPPSCK 407
C P N G+D+ VG+ + + C + ++L G KS C++ WS P C+
Sbjct: 349 CLDPGIPENGRRAGSDFSRVGANVQFSCEDNYVLQGSKSITCQRVTETLAAWSDHRPICR 408
Query: 408 YVNCG 412
CG
Sbjct: 409 ARTCG 413
Score = 33.1 bits (72), Expect = 5.6
Identities = 21/99 (21%), Positives = 40/99 (40%), Gaps = 8/99 (8%)
Query: 527 VNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGK--WSYDIPSC- 583
V C P I + + + ++ ++C P Y ++G+ L C + W +PSC
Sbjct: 1216 VKCEDPGIPNYGYRIRDEGHFTDTVVLYSCNPGYAMHGSNTLTCLSGDRRVWDKPLPSCI 1275
Query: 584 -----ELTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAG 617
++ + + S GY +D +H T + G
Sbjct: 1276 AECGGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPG 1314
Score = 33.1 bits (72), Expect = 5.6
Identities = 18/65 (27%), Positives = 32/65 (49%), Gaps = 5/65 (7%)
Query: 587 SCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVC--QQDGE--WSGDSPTCE 642
+C +P G D+ + STI + C++G+K++ ++ C DG+ W P+C
Sbjct: 1564 ACFDPGNIMNGTRVGTDFKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLPSCN 1623
Query: 643 YIDCG 647
CG
Sbjct: 1624 -APCG 1627
Score = 33.1 bits (72), Expect = 5.6
Identities = 17/68 (25%), Positives = 32/68 (47%), Gaps = 3/68 (4%)
Query: 734 SDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDN--GQWSGTTPTCQYVDCGNPGRI 791
S++ +G+ Y + ++ ++CE GY + G S +C +W+ +P C CG
Sbjct: 1924 SNSIKIGDRYMVNDVLSFQCEPGYTLQGRSHISCMPGTVRRWNYPSPLC-IATCGGTLST 1982
Query: 792 ENGKVTLP 799
G + P
Sbjct: 1983 LGGVILSP 1990
Score = 32.7 bits (71), Expect = 7.4
Identities = 15/57 (26%), Positives = 23/57 (40%), Gaps = 3/57 (5%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
CG P +P + + + + G +EC +EL G R C W+ P C
Sbjct: 528 CGDPGIPAYGKRT---GSSFLHGDTLTFECPAAFELVGERVITCQQNNQWSGNKPSC 581
Score = 32.3 bits (70), Expect = 9.7
Identities = 15/57 (26%), Positives = 26/57 (45%), Gaps = 3/57 (5%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
CG P +P R+S ++ + ++C + L G+ +R C G W+ P C
Sbjct: 3157 CGDPGIPAEGRLS---GKSFTYKSEVFFQCKSPFILVGSSRRVCQADGTWSGIQPTC 3210
>AB209502-1|BAD92739.1| 2966|Homo sapiens CUB and Sushi multiple
domains 1 variant protein.
Length = 2966
Score = 316 bits (777), Expect = 2e-85
Identities = 198/638 (31%), Positives = 286/638 (44%), Gaps = 49/638 (7%)
Query: 347 QYLPPTCGSPDKLLNTTILGNDYD-VGSRIVYKCPEGHMLLGDKSRHCKKDGF----WSG 401
+Y P C L N IL VGS++ Y C G+ ++G + C+++ W
Sbjct: 1843 RYAAPYCSLTHPLKNGGILNRTAGAVGSKVHYFCKPGYRMVGHSNATCRRNPLGMYQWDS 1902
Query: 402 APPSCKYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERT--CGDEGIW 459
P C+ V+CG P G+ + N T ++ +Y C E F L + + T C ++G+W
Sbjct: 1903 LTPLCQAVSCG--IPESPGNGSFTGNEFTLDSKVVYECHEGFKLESSQQATAVCQEDGLW 1960
Query: 460 D--GEAPRCLFDWCPDPPAVSNASVT---VNG--HKAGSLASYTCENGHILSGSTSVTCT 512
G+ P C CP A + V V+G ++ G+ +C G+ L G + C
Sbjct: 1961 SNKGKPPMCKPVACPSIEAQLSEHVIWRLVSGSLNEYGAQVLLSCSPGYYLEGWRLLRCQ 2020
Query: 513 LGGAWS--GVPPSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVC 570
G W+ PSC+ ++CG+ + I T YG+ A FTC Y L G+ C
Sbjct: 2021 ANGTWNIGDERPSCRVISCGSLSFPPNGNK-IGTLTVYGATAIFTCNTGYTLVGSHVREC 2079
Query: 571 NRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQ 630
+G WS C C P+ G++ + T+ + C G +L+G +C Q
Sbjct: 2080 LANGLWSGSETRCLAGHCGSPDPIVNGHISGDGFSYRDTVVYQCNPGFRLVGTSVRICLQ 2139
Query: 631 DGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTT-HLGSVIQYSCTTNYRLVGPVRRTCT 689
D +WSG +P C I CG +G NG+ +L V+ ++C T Y L G R C
Sbjct: 2140 DHKWSGQTPVCVPITCGHPGNPAHG---FTNGSEFNLNDVVNFTCNTGYLLQGVSRAQCR 2196
Query: 690 EEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALV 749
QWS P C + CSDP E +I HG ++ ++ G +
Sbjct: 2197 SNGQWSSPLPTCRVVNCSDPGFVENAI--------RHGQ--------QNFPESFEYGMSI 2240
Query: 750 KYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATA 809
Y C+KG+ ++G S TC NG W + P C + CG+PG N +T YGA
Sbjct: 2241 LYHCKKGFYLLGSSALTCMANGLWDRSLPKCLAISCGHPGVPANAVLT--GELFTYGAVV 2298
Query: 810 FYQCDENWELEGVIRRMCQENGTWSLEPPICKEIT---CPDPSAQIKAGSGLLVVTSTLS 866
Y C + L G R+CQE+ WS P C C DP GS L T S
Sbjct: 2299 HYSCRGSESLIGNDTRVCQEDSHWSGALPHCTGNNPGFCGDPGTPAH-GSRLGDDFKTKS 2357
Query: 867 IGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTL 926
+ + CE G+ L+G RTC+ G W+G PVC + C +PG NG IV S+G L
Sbjct: 2358 L---LRFSCEMGHQLRGSPERTCLLNGSWSGLQPVCEAVSCGNPGTPTNGMIVSSDG-IL 2413
Query: 927 FGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCEL 964
F SSV Y C Y+ G R C +G W+G P C +
Sbjct: 2414 FSSSVIYACWEGYKTSGLMTRHCTANGTWTGTAPDCTI 2451
Score = 299 bits (733), Expect = 5e-80
Identities = 183/633 (28%), Positives = 284/633 (44%), Gaps = 45/633 (7%)
Query: 349 LPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKY 408
+P TCG P + G+++++ + + C G++L G C+ +G WS P+C+
Sbjct: 2151 VPITCGHPGNPAHGFTNGSEFNLNDVVNFTCNTGYLLQGVSRAQCRSNGQWSSPLPTCRV 2210
Query: 409 VNCGGLTPIEDG---DVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPR 465
VNC +E+ +G LY C++ F L+G+ TC G+WD P+
Sbjct: 2211 VNCSDPGFVENAIRHGQQNFPESFEYGMSILYHCKKGFYLLGSSALTCMANGLWDRSLPK 2270
Query: 466 CLFDWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCK 525
CL C P +NA +T G++ Y+C L G+ + C WSG P C
Sbjct: 2271 CLAISCGHPGVPANAVLTGELFTYGAVVHYSCRGSESLIGNDTRVCQEDSHWSGALPHCT 2330
Query: 526 YVN---CGTP-TIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIP 581
N CG P T GS + + T S+ +F+CE + L G+ E C +G WS P
Sbjct: 2331 GNNPGFCGDPGTPAHGSRLGDDFKTK--SLLRFSCEMGHQLRGSPERTCLLNGSWSGLQP 2388
Query: 582 SCELTSCPEPEVPSGGYMEAFD-YYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPT 640
CE SC P P+ G + + D S++ + C G+K G C +G W+G +P
Sbjct: 2389 VCEAVSCGNPGTPTNGMIVSSDGILFSSSVIYACWEGYKTSGLMTRHCTANGTWTGTAPD 2448
Query: 641 CEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRT--CTEEFQWSDSS 698
C I CG TL G + T + Y C Y + T CT++ +W+ S
Sbjct: 2449 CTIISCGDPGTLANGIQFGTDFT--FNKTVSYQCNPGYVMEAVTSATIRCTKDGRWNPSK 2506
Query: 699 PRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYK 758
P C+ + C P + V G+ +R G+ + Y C GY+
Sbjct: 2507 PVCKAVLCPQPPPVQNGTVE---------------------GSDFRWGSSISYSCMDGYQ 2545
Query: 759 VIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWE 818
+ ++ +CE G W G P C V CG+PG G+ L + Y + F+QC +
Sbjct: 2546 LSHSAILSCEGRGVWKGEIPQCLPVFCGDPGIPAEGR--LSGKSFTYKSEVFFQCKSPFI 2603
Query: 819 LEGVIRRMCQENGTWSLEPPIC---KEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQC 875
L G RR+CQ +GTWS P C TCPDP G+ + +G ++C
Sbjct: 2604 LVGSSRRVCQADGTWSGIQPTCIDPAHNTCPDPGT---PHFGIQNSSRGYEVGSTVFFRC 2660
Query: 876 ERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYC 935
+GY+++G TRTC++ W+G CIP CR P + + + T FG ++ Y C
Sbjct: 2661 RKGYHIQGSTTRTCLANLTWSGIQTECIPHACRQPETPAHADVRAIDLPT-FGYTLVYTC 2719
Query: 936 LSQYQRV-GPFLRKCLDDGRWSGEEPSCELATN 967
+ G R C D +W+G+ P C++ ++
Sbjct: 2720 HPGFFLAGGSEHRTCKADMKWTGKSPVCKIPSD 2752
Score = 284 bits (696), Expect = 1e-75
Identities = 182/623 (29%), Positives = 259/623 (41%), Gaps = 45/623 (7%)
Query: 353 CGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCG 412
CGSPD ++N I G+ + +VY+C G L+G R C +D WSG P C + CG
Sbjct: 2097 CGSPDPIVNGHISGDGFSYRDTVVYQCNPGFRLVGTSVRICLQDHKWSGQTPVCVPITCG 2156
Query: 413 GLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCP 472
P + ++C + L G C G W P C C
Sbjct: 2157 --HPGNPAHGFTNGSEFNLNDVVNFTCNTGYLLQGVSRAQCRSNGQWSSPLPTCRVVNCS 2214
Query: 473 DPPAVSNA-----SVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYV 527
DP V NA + G Y C+ G L GS+++TC G W P C +
Sbjct: 2215 DPGFVENAIRHGQQNFPESFEYGMSILYHCKKGFYLLGSSALTCMANGLWDRSLPKCLAI 2274
Query: 528 NCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTS 587
+CG P + + VL TYG++ ++C L G + VC D WS +P C +
Sbjct: 2275 SCGHPGV-PANAVLTGELFTYGAVVHYSCRGSESLIGNDTRVCQEDSHWSGALPHCTGNN 2333
Query: 588 ---CPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYI 644
C +P P+ G D+ S + F CE GH+L G P C +G WSG P CE +
Sbjct: 2334 PGFCGDPGTPAHGSRLGDDFKTKSLLRFSCEMGHQLRGSPERTCLLNGSWSGLQPVCEAV 2393
Query: 645 DCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEI 704
CG T G + +G SVI Y+C Y+ G + R CT W+ ++P C I
Sbjct: 2394 SCGNPGTPTNGMIVSSDGILFSSSVI-YACWEGYKTSGLMTRHCTANGTWTGTAPDCTII 2452
Query: 705 RCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGY--KVIGE 762
C DP I G + V Y+C GY + +
Sbjct: 2453 SCGDPGTLANGI---------------------QFGTDFTFNKTVSYQCNPGYVMEAVTS 2491
Query: 763 SLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGV 822
+ C +G+W+ + P C+ V C P ++NG T+ + +G++ Y C + ++L
Sbjct: 2492 ATIRCTKDGRWNPSKPVCKAVLCPQPPPVQNG--TVEGSDFRWGSSISYSCMDGYQLSHS 2549
Query: 823 IRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLK 882
C+ G W E P C + C DP I A L + T E +QC+ + L
Sbjct: 2550 AILSCEGRGVWKGEIPQCLPVFCGDPG--IPAEGRLSGKSFTYK--SEVFFQCKSPFILV 2605
Query: 883 GHQTRTCISKGQWNGTVPVCI-PI--DCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQY 939
G R C + G W+G P CI P C PG G S G + GS+V + C Y
Sbjct: 2606 GSSRRVCQADGTWSGIQPTCIDPAHNTCPDPGTPHFGIQNSSRGYEV-GSTVFFRCRKGY 2664
Query: 940 QRVGPFLRKCLDDGRWSGEEPSC 962
G R CL + WSG + C
Sbjct: 2665 HIQGSTTRTCLANLTWSGIQTEC 2687
Score = 220 bits (537), Expect = 3e-56
Identities = 175/620 (28%), Positives = 265/620 (42%), Gaps = 68/620 (10%)
Query: 367 NDYDVGSRIVYKCPEGHMLLGDKSRHCKKDG--FWSGAPPSCKYVNCGGLTPIEDGDVAL 424
+D+++G + Y+C G+ L+G CK + G+ P+C+ G +P+ V L
Sbjct: 1754 DDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPTCE--GSSGQSPLL---VVL 1808
Query: 425 IDNRTTHGARALYSCREN-FTLVGNPERTCGDEGI-WDGEAPRCLFDWCPDPPAVSNASV 482
N H ++ ++ R N L + + +G AP C P + +
Sbjct: 1809 SGN---HTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRYAAPYCSL----THPLKNGGIL 1861
Query: 483 TVNGHKAGSLASYTCENGHILSGSTSVTC---TLG-GAWSGVPPSCKYVNCGTP-TIHKG 537
GS Y C+ G+ + G ++ TC LG W + P C+ V+CG P + G
Sbjct: 1862 NRTAGAVGSKVHYFCKPGYRMVGHSNATCRRNPLGMYQWDSLTPLCQAVSCGIPESPGNG 1921
Query: 538 SFVLINGTTTYGSIAQFTCEPDYWLNGAEE--LVCNRDGKWSY--DIPSCELTSCPEPEV 593
SF T S + C + L +++ VC DG WS P C+ +CP E
Sbjct: 1922 SFT--GNEFTLDSKVVYECHEGFKLESSQQATAVCQEDGLWSNKGKPPMCKPVACPSIEA 1979
Query: 594 PSGGYM------EAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWS-GDS-PTCEYID 645
++ + + Y + + C G+ L G L CQ +G W+ GD P+C I
Sbjct: 1980 QLSEHVIWRLVSGSLNEY-GAQVLLSCSPGYYLEGWRLLRCQANGTWNIGDERPSCRVIS 2038
Query: 646 CGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIR 705
CG L P G + T G+ ++C T Y LVG R C WS S RC
Sbjct: 2039 CGSLSFPPNGNK--IGTLTVYGATAIFTCNTGYTLVGSHVRECLANGLWSGSETRCLAGH 2096
Query: 706 CS--DPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGES 763
C DPIV +GH + D G +YR V Y+C G++++G S
Sbjct: 2097 CGSPDPIV--------------NGHI---SGD----GFSYR--DTVVYQCNPGFRLVGTS 2133
Query: 764 LSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVI 823
+ C + +WSG TP C + CG+PG +G T S F C+ + L+GV
Sbjct: 2134 VRICLQDHKWSGQTPVCVPITCGHPGNPAHG-FTNGSEFNLNDVVNF-TCNTGYLLQGVS 2191
Query: 824 RRMCQENGTWSLEPPICKEITCPDPS-AQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLK 882
R C+ NG WS P C+ + C DP + G + G Y C++G+ L
Sbjct: 2192 RAQCRSNGQWSSPLPTCRVVNCSDPGFVENAIRHGQQNFPESFEYGMSILYHCKKGFYLL 2251
Query: 883 GHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRV 942
G TC++ G W+ ++P C+ I C PG N V++ +G+ V Y C +
Sbjct: 2252 GSSALTCMANGLWDRSLPKCLAISCGHPGVPANA--VLTGELFTYGAVVHYSCRGSESLI 2309
Query: 943 GPFLRKCLDDGRWSGEEPSC 962
G R C +D WSG P C
Sbjct: 2310 GNDTRVCQEDSHWSGALPHC 2329
Score = 83.0 bits (196), Expect = 5e-15
Identities = 54/187 (28%), Positives = 80/187 (42%), Gaps = 8/187 (4%)
Query: 345 ICQYLPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPP 404
I Q LP CG P + G + S + ++C +L+G R C+ DG WSG P
Sbjct: 2564 IPQCLPVFCGDPGIPAEGRLSGKSFTYKSEVFFQCKSPFILVGSSRRVCQADGTWSGIQP 2623
Query: 405 SCKYVNCGGLTPIEDGDVAL-IDNRTTH---GARALYSCRENFTLVGNPERTCGDEGIWD 460
+C ++ T + G I N + G+ + CR+ + + G+ RTC W
Sbjct: 2624 TC--IDPAHNTCPDPGTPHFGIQNSSRGYEVGSTVFFRCRKGYHIQGSTTRTCLANLTWS 2681
Query: 461 GEAPRCLFDWCPDPPAVSNASV-TVNGHKAGSLASYTCENGHILS-GSTSVTCTLGGAWS 518
G C+ C P ++A V ++ G YTC G L+ GS TC W+
Sbjct: 2682 GIQTECIPHACRQPETPAHADVRAIDLPTFGYTLVYTCHPGFFLAGGSEHRTCKADMKWT 2741
Query: 519 GVPPSCK 525
G P CK
Sbjct: 2742 GKSPVCK 2748
Score = 70.5 bits (165), Expect = 3e-11
Identities = 77/334 (23%), Positives = 129/334 (38%), Gaps = 50/334 (14%)
Query: 646 CGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTC--TEEFQWSDSSPRCEE 703
C P +P M + +G ++Y C Y LVG TC + + Q+ S P CE
Sbjct: 1738 CQPPPAVPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPTCEG 1797
Query: 704 IRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGES 763
P+ +V ++GN + R++ Y + +KG+K+
Sbjct: 1798 SSGQSPL-----LVVLSGNHTEQSNFTSRSN------QLYLRWSTDHATSKKGFKI---- 1842
Query: 764 LSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVI 823
P C +P ++NG + L A G+ Y C + + G
Sbjct: 1843 ----------RYAAPYCSLT---HP--LKNGGI-LNRTAGAVGSKVHYFCKPGYRMVGHS 1886
Query: 824 RRMCQENG----TWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGY 879
C+ N W P+C+ ++C P + G+G + ++ + Y+C G+
Sbjct: 1887 NATCRRNPLGMYQWDSLTPLCQAVSCGIPES---PGNGSF-TGNEFTLDSKVVYECHEGF 1942
Query: 880 NLKGHQ--TRTCISKGQWN--GTVPVCIPIDCRS-PGNIENGKI--VISNGSTLFGSSVE 932
L+ Q T C G W+ G P+C P+ C S + I ++S +G+ V
Sbjct: 1943 KLESSQQATAVCQEDGLWSNKGKPPMCKPVACPSIEAQLSEHVIWRLVSGSLNEYGAQVL 2002
Query: 933 YYCLSQYQRVGPFLRKCLDDGRWS--GEEPSCEL 964
C Y G L +C +G W+ E PSC +
Sbjct: 2003 LSCSPGYYLEGWRLLRCQANGTWNIGDERPSCRV 2036
Score = 58.8 bits (136), Expect = 1e-07
Identities = 64/242 (26%), Positives = 92/242 (38%), Gaps = 18/242 (7%)
Query: 353 CGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHC--KKDG--FWSGAPPSCKY 408
C P ++N T +G D+ +GS I Y+C G+ +L S C DG W PSC
Sbjct: 1044 CFDPGNIMNGTRVGTDFKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLPSCN- 1102
Query: 409 VNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLF 468
CGG +G V L N H A C + T+ E + + A L
Sbjct: 1103 APCGGQYTGSEG-VVLSPN-YPHNYTAGQICLYSITV--PKEFVVFGQFAYFQTALNDLA 1158
Query: 469 DWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGG---AWSGVPPSCK 525
+ A + +++G +G N +L S + G + VP +
Sbjct: 1159 ELFDGTHAQARLLSSLSGSHSGETLPLATSNQILLRFSAKSGASARGFHFVYQAVPRTSD 1218
Query: 526 YVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVC----NRDGKWSYDIP 581
P G I + GSI +F C P Y L G+ L C N +W+ IP
Sbjct: 1219 TQCSSVPEPRYGR--RIGSEFSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQWNDTIP 1276
Query: 582 SC 583
SC
Sbjct: 1277 SC 1278
Score = 56.0 bits (129), Expect = 7e-07
Identities = 22/70 (31%), Positives = 41/70 (58%), Gaps = 1/70 (1%)
Query: 578 YDIPSCELTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGD 637
Y+ + E SC +P +P G+ D+ + ST+ F C+ G+ L + LVC+++ +W+
Sbjct: 343 YESVTLESDSCLDPGIPVNGHRHGGDFGIRSTVTFSCDPGYTLSDDEPLVCERNHQWNHA 402
Query: 638 SPTCEYIDCG 647
P+C+ + CG
Sbjct: 403 LPSCDAL-CG 411
Score = 55.6 bits (128), Expect = 9e-07
Identities = 34/90 (37%), Positives = 46/90 (51%), Gaps = 6/90 (6%)
Query: 571 NRDG-KWSYDIPSCELTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQ 629
NR G K +Y + EL +CP+P GYM DY V +++F C G+ LIG P L CQ
Sbjct: 1551 NRQGFKLAYQ--AYELQNCPDPPPFQNGYMINSDYSVGQSVSFECYPGYILIGHPVLTCQ 1608
Query: 630 Q--DGEWSGDSPTCEYIDCGKLPTLPYGTM 657
+ W+ P C+ CG T GT+
Sbjct: 1609 HGINRNWNYPFPRCD-APCGYNVTSQNGTI 1637
Score = 53.2 bits (122), Expect = 5e-06
Identities = 20/60 (33%), Positives = 33/60 (55%)
Query: 584 ELTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEY 643
E C +P +P+ G + T+ F C A +L+GE + CQQ+ +WSG+ P+C +
Sbjct: 3 EKGGCGDPGIPAYGKRTGSSFLHGDTLTFECPAAFELVGERVITCQQNNQWSGNKPSCVF 62
Score = 47.6 bits (108), Expect = 2e-04
Identities = 24/76 (31%), Positives = 36/76 (47%), Gaps = 3/76 (3%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTN 61
CG+P P N I + + I+ + +Y C EGY+ G R CT G WT P C T
Sbjct: 2395 CGNPGTPTNGM--IVSSDGILFSSSVIYACWEGYKTSGLMTRHCTANGTWTGTAPDC-TI 2451
Query: 62 VAFRKPANQSTTVRGG 77
++ P + ++ G
Sbjct: 2452 ISCGDPGTLANGIQFG 2467
Score = 46.0 bits (104), Expect = 7e-04
Identities = 19/67 (28%), Positives = 35/67 (52%), Gaps = 1/67 (1%)
Query: 740 GNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLP 799
G+++ G + + C ++++GE + TC+ N QWSG P+C + C +G + P
Sbjct: 20 GSSFLHGDTLTFECPAAFELVGERVITCQQNNQWSGNKPSCVF-SCFFNFTASSGIILSP 78
Query: 800 SNATFYG 806
+ YG
Sbjct: 79 NYPEEYG 85
Score = 43.2 bits (97), Expect = 0.005
Identities = 23/70 (32%), Positives = 32/70 (45%), Gaps = 2/70 (2%)
Query: 585 LTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQD--GEWSGDSPTCE 642
L +C EP +PS Y V+ ++F CE G+ L G ++ C W+ SP C
Sbjct: 1392 LAACQEPALPSNSIKIGDRYMVNDVLSFQCEPGYTLQGRSHISCMPGTVRRWNYPSPLCI 1451
Query: 643 YIDCGKLPTL 652
G L TL
Sbjct: 1452 ATCGGTLSTL 1461
Score = 42.3 bits (95), Expect = 0.009
Identities = 15/35 (42%), Positives = 24/35 (68%)
Query: 550 SIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCE 584
S F+C+P Y L+ E LVC R+ +W++ +PSC+
Sbjct: 373 STVTFSCDPGYTLSDDEPLVCERNHQWNHALPSCD 407
Score = 41.9 bits (94), Expect = 0.012
Identities = 29/120 (24%), Positives = 47/120 (39%), Gaps = 8/120 (6%)
Query: 297 VDGELVSKPSWGKDQPNNYNGEQNCVVLDGGRGWLWNDVGCNLDYLHWICQYLPPTCGSP 356
VD +++ K G P + + N + L + + G ++ + I TC P
Sbjct: 819 VDSDILLKEWSGSALPEDIHSTFNSLTLQFDSDFFISKSGFSIQFSTSIAA----TCNDP 874
Query: 357 DKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHC---KKDGFWSGAPPSCKYVNCGG 413
N T G+ + G + ++C G+ L G C FW PP+C CGG
Sbjct: 875 GMPQNGTRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTC-IAACGG 933
Score = 41.5 bits (93), Expect = 0.016
Identities = 21/71 (29%), Positives = 35/71 (49%), Gaps = 1/71 (1%)
Query: 352 TCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNC 411
+C P +N G D+ + S + + C G+ L D+ C+++ W+ A PSC + C
Sbjct: 352 SCLDPGIPVNGHRHGGDFGIRSTVTFSCDPGYTLSDDEPLVCERNHQWNHALPSCDAL-C 410
Query: 412 GGLTPIEDGDV 422
GG + G V
Sbjct: 411 GGYIQGKSGTV 421
Score = 41.5 bits (93), Expect = 0.016
Identities = 20/66 (30%), Positives = 32/66 (48%), Gaps = 1/66 (1%)
Query: 740 GNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLP 799
G + I + V + C+ GY + + CE N QW+ P+C + CG + ++G V P
Sbjct: 366 GGDFGIRSTVTFSCDPGYTLSDDEPLVCERNHQWNHALPSCDAL-CGGYIQGKSGTVLSP 424
Query: 800 SNATFY 805
FY
Sbjct: 425 GFPDFY 430
Score = 41.5 bits (93), Expect = 0.016
Identities = 21/73 (28%), Positives = 33/73 (45%), Gaps = 5/73 (6%)
Query: 739 VGNTYRIGALVKYRCEKGYKVIGESLSTC----EDNGQWSGTTPTCQYVDCGNPGRIENG 794
VG +++G+ + Y+C+ GYK++ S TC + W P+C CG G
Sbjct: 1056 VGTDFKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLPSCN-APCGGQYTGSEG 1114
Query: 795 KVTLPSNATFYGA 807
V P+ Y A
Sbjct: 1115 VVLSPNYPHNYTA 1127
Score = 40.7 bits (91), Expect = 0.028
Identities = 22/74 (29%), Positives = 32/74 (43%), Gaps = 4/74 (5%)
Query: 587 SCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGE---WSGDSPTCEY 643
+C +P +P G T+ F C+ G++L G+ + C Q W D PTC
Sbjct: 870 TCNDPGMPQNGTRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTC-I 928
Query: 644 IDCGKLPTLPYGTM 657
CG T P G +
Sbjct: 929 AACGGNLTGPAGVI 942
Score = 39.9 bits (89), Expect = 0.049
Identities = 21/66 (31%), Positives = 30/66 (45%), Gaps = 3/66 (4%)
Query: 584 ELTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGE--WSGDSPTC 641
+L C +P VP+ F + V ++ F C G++L G L C G WS P C
Sbjct: 521 DLEPCDDPGVPAFSRRIGFHFGVGDSLTFSCFLGYRLEGATKLTCLGGGRRVWSAPLPRC 580
Query: 642 EYIDCG 647
+CG
Sbjct: 581 -VAECG 585
Score = 39.1 bits (87), Expect = 0.085
Identities = 16/56 (28%), Positives = 28/56 (50%)
Query: 353 CGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKY 408
CG P G+ + G + ++CP L+G++ C+++ WSG PSC +
Sbjct: 7 CGDPGIPAYGKRTGSSFLHGDTLTFECPAAFELVGERVITCQQNNQWSGNKPSCVF 62
Score = 39.1 bits (87), Expect = 0.085
Identities = 21/62 (33%), Positives = 28/62 (45%), Gaps = 3/62 (4%)
Query: 471 CPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLG--GAWSGVPPSCKYVN 528
CPDPP N + + + G S+ C G+IL G +TC G W+ P C
Sbjct: 1567 CPDPPPFQNGYMINSDYSVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYPFPRCD-AP 1625
Query: 529 CG 530
CG
Sbjct: 1626 CG 1627
Score = 38.7 bits (86), Expect = 0.11
Identities = 20/74 (27%), Positives = 33/74 (44%), Gaps = 5/74 (6%)
Query: 737 RDVGNTYRIGALVKYRCEKGYKVIGESLSTCED----NGQWSGTTPTCQYVDCGNPGRIE 792
R +G+ + G++V++ C GY + G + C+ QW+ T P+C V C
Sbjct: 1231 RRIGSEFSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQWNDTIPSC-VVPCSGNFTQR 1289
Query: 793 NGKVTLPSNATFYG 806
G + P YG
Sbjct: 1290 RGTILSPGYPEPYG 1303
Score = 38.7 bits (86), Expect = 0.11
Identities = 19/63 (30%), Positives = 29/63 (46%), Gaps = 3/63 (4%)
Query: 739 VGNTYRIGALVKYRCEKGYKVIGESLSTCED--NGQWSGTTPTCQYVDCGNPGRIENGKV 796
+ + Y +G V + C GY +IG + TC+ N W+ P C CG +NG +
Sbjct: 1579 INSDYSVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYPFPRCD-APCGYNVTSQNGTI 1637
Query: 797 TLP 799
P
Sbjct: 1638 YSP 1640
Score = 38.3 bits (85), Expect = 0.15
Identities = 20/56 (35%), Positives = 28/56 (50%), Gaps = 2/56 (3%)
Query: 785 CGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPIC 840
CG+PG GK T ++ +G T ++C +EL G CQ+N WS P C
Sbjct: 7 CGDPGIPAYGKRT--GSSFLHGDTLTFECPAAFELVGERVITCQQNNQWSGNKPSC 60
Score = 37.5 bits (83), Expect = 0.26
Identities = 18/56 (32%), Positives = 29/56 (51%), Gaps = 2/56 (3%)
Query: 907 CRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
C PG GK + S L G ++ + C + ++ VG + C + +WSG +PSC
Sbjct: 7 CGDPGIPAYGKR--TGSSFLHGDTLTFECPAAFELVGERVITCQQNNQWSGNKPSC 60
Score = 37.5 bits (83), Expect = 0.26
Identities = 22/64 (34%), Positives = 25/64 (39%), Gaps = 4/64 (6%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC-GT 60
CGHP VP NA + E G + Y C L G R C W+ P C G
Sbjct: 2276 CGHPGVPANA---VLTGELFTYGAVVHYSCRGSESLIGNDTRVCQEDSHWSGALPHCTGN 2332
Query: 61 NVAF 64
N F
Sbjct: 2333 NPGF 2336
Score = 36.7 bits (81), Expect = 0.45
Identities = 23/86 (26%), Positives = 40/86 (46%), Gaps = 9/86 (10%)
Query: 336 GCNLDYLHWICQYLPPT----CGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSR 391
G + H++ Q +P T C S + +G+++ GS + ++C G++L G +
Sbjct: 1200 GASARGFHFVYQAVPRTSDTQCSSVPEPRYGRRIGSEFSAGSIVRFECNPGYLLQGSTAL 1259
Query: 392 HCKKD----GFWSGAPPSCKYVNCGG 413
HC+ W+ PSC V C G
Sbjct: 1260 HCQSVPNALAQWNDTIPSC-VVPCSG 1284
Score = 36.7 bits (81), Expect = 0.45
Identities = 51/238 (21%), Positives = 83/238 (34%), Gaps = 15/238 (6%)
Query: 471 CPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGA--WSGVPPSCKYVN 528
C +P SN+ + + + S+ CE G+ L G + ++C G W+ P C
Sbjct: 1395 CQEPALPSNSIKIGDRYMVNDVLSFQCEPGYTLQGRSHISCMPGTVRRWNYPSPLC-IAT 1453
Query: 529 CGTPTIHKGSFVLING-TTTYGSIAQFTCEPDYWLN-GAEELVCNRDGKWSYDIPSCELT 586
CG G +L G +Y + T + GA N + ++D E+
Sbjct: 1454 CGGTLSTLGGVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTEANHDF--LEIQ 1511
Query: 587 SCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDC 646
+ P P G D H LI + Q + E +C
Sbjct: 1512 NGPYHTSPMIGQFSGTDLPAALLSTTH----ETLIHFYSDHSQNRQGFKLAYQAYELQNC 1567
Query: 647 GKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEF--QWSDSSPRCE 702
P P+ ++N +G + + C Y L+G TC W+ PRC+
Sbjct: 1568 PDPP--PFQNGYMINSDYSVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYPFPRCD 1623
Score = 36.7 bits (81), Expect = 0.45
Identities = 18/51 (35%), Positives = 24/51 (47%), Gaps = 3/51 (5%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWT 52
CG + PPN V G A++ C+ GY L G+ REC G W+
Sbjct: 2039 CGSLSFPPNGNKI---GTLTVYGATAIFTCNTGYTLVGSHVRECLANGLWS 2086
Score = 36.3 bits (80), Expect = 0.60
Identities = 20/59 (33%), Positives = 30/59 (50%), Gaps = 5/59 (8%)
Query: 785 CGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMC-QENGT--WSLEPPIC 840
C +PG +NG T ++ G T +QCD ++L+G + C Q N W +PP C
Sbjct: 871 CNDPGMPQNG--TRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTC 927
Score = 35.9 bits (79), Expect = 0.79
Identities = 20/64 (31%), Positives = 29/64 (45%), Gaps = 6/64 (9%)
Query: 471 CPDPPAVSNASVTVN--GHKAGSLASYTCENGHILSGSTSVTCTLGG--AWSGVPPSCKY 526
C DP + N + GH ++ Y+C G+ + GS ++TC G W PSC
Sbjct: 697 CEDP-GIPNYGYRIRDEGHFTDTVVLYSCNPGYAMHGSNTLTCLSGDRRVWDKPLPSC-I 754
Query: 527 VNCG 530
CG
Sbjct: 755 AECG 758
Score = 35.9 bits (79), Expect = 0.79
Identities = 19/63 (30%), Positives = 28/63 (44%), Gaps = 4/63 (6%)
Query: 471 CPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCT-LGGA--WSGVPPSCKYV 527
C DP N + + +AG ++ C+ G+ L G +TC L W PP+C
Sbjct: 871 CNDPGMPQNGTRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTC-IA 929
Query: 528 NCG 530
CG
Sbjct: 930 ACG 932
Score = 35.5 bits (78), Expect = 1.0
Identities = 16/57 (28%), Positives = 23/57 (40%), Gaps = 3/57 (5%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
CGHP P + N + + C+ GY L G + +C G W+ P C
Sbjct: 2155 CGHPGNPAHG---FTNGSEFNLNDVVNFTCNTGYLLQGVSRAQCRSNGQWSSPLPTC 2208
Score = 35.1 bits (77), Expect = 1.4
Identities = 21/80 (26%), Positives = 29/80 (36%)
Query: 471 CPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCG 530
C DP + T + G ++ C L G +TC WSG PSC +
Sbjct: 7 CGDPGIPAYGKRTGSSFLHGDTLTFECPAAFELVGERVITCQQNNQWSGNKPSCVFSCFF 66
Query: 531 TPTIHKGSFVLINGTTTYGS 550
T G + N YG+
Sbjct: 67 NFTASSGIILSPNYPEEYGN 86
Score = 35.1 bits (77), Expect = 1.4
Identities = 22/96 (22%), Positives = 35/96 (36%), Gaps = 7/96 (7%)
Query: 639 PTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEE----FQW 694
P C +P YG + GS++++ C Y L G C QW
Sbjct: 1214 PRTSDTQCSSVPEPRYGRR--IGSEFSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQW 1271
Query: 695 SDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTL 730
+D+ P C + CS + + G +G+ L
Sbjct: 1272 NDTIPSC-VVPCSGNFTQRRGTILSPGYPEPYGNNL 1306
Score = 34.7 bits (76), Expect = 1.8
Identities = 25/82 (30%), Positives = 35/82 (42%), Gaps = 13/82 (15%)
Query: 469 DWCPDPPAVSNASVTVNGHKAG------SLASYTCENGHILSGSTSVTCTLGGAWSGVPP 522
D C DP + VNGH+ G S +++C+ G+ LS + C W+ P
Sbjct: 351 DSCLDP------GIPVNGHRHGGDFGIRSTVTFSCDPGYTLSDDEPLVCERNHQWNHALP 404
Query: 523 SCKYVNCGTPTIHKGSFVLING 544
SC + CG K VL G
Sbjct: 405 SCDAL-CGGYIQGKSGTVLSPG 425
Score = 34.7 bits (76), Expect = 1.8
Identities = 19/72 (26%), Positives = 34/72 (47%), Gaps = 3/72 (4%)
Query: 736 NRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQ--WSGTTPTCQYVDCGNPGRIEN 793
+R +G + +G + + C GY++ G + TC G+ WS P C +CG +
Sbjct: 534 SRRIGFHFGVGDSLTFSCFLGYRLEGATKLTCLGGGRRVWSAPLPRC-VAECGASVKGNE 592
Query: 794 GKVTLPSNATFY 805
G + P+ + Y
Sbjct: 593 GTLLSPNFPSNY 604
Score = 34.7 bits (76), Expect = 1.8
Identities = 17/69 (24%), Positives = 31/69 (44%), Gaps = 4/69 (5%)
Query: 582 SCELTSCPEPEVPSGGY-MEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGE--WSGDS 638
S +L C +P +P+ GY + ++ + + + C G+ + G L C W
Sbjct: 691 SFDLVKCEDPGIPNYGYRIRDEGHFTDTVVLYSCNPGYAMHGSNTLTCLSGDRRVWDKPL 750
Query: 639 PTCEYIDCG 647
P+C +CG
Sbjct: 751 PSC-IAECG 758
Score = 34.7 bits (76), Expect = 1.8
Identities = 20/75 (26%), Positives = 32/75 (42%), Gaps = 5/75 (6%)
Query: 861 VTSTLSIGGEAHYQCERGYNLKGHQTRTCIS----KGQWNGTVPVCIPIDCRSPGNIENG 916
+ S S G ++C GY L+G C S QWN T+P C+ + C G
Sbjct: 1233 IGSEFSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQWNDTIPSCV-VPCSGNFTQRRG 1291
Query: 917 KIVISNGSTLFGSSV 931
I+ +G+++
Sbjct: 1292 TILSPGYPEPYGNNL 1306
Score = 34.7 bits (76), Expect = 1.8
Identities = 20/66 (30%), Positives = 33/66 (50%), Gaps = 4/66 (6%)
Query: 489 AGSLASYTCENGHILSGSTSVTC-TLGGA---WSGVPPSCKYVNCGTPTIHKGSFVLING 544
AGS+ + C G++L GST++ C ++ A W+ PSC G T +G+ +
Sbjct: 1239 AGSIVRFECNPGYLLQGSTALHCQSVPNALAQWNDTIPSCVVPCSGNFTQRRGTILSPGY 1298
Query: 545 TTTYGS 550
YG+
Sbjct: 1299 PEPYGN 1304
Score = 34.7 bits (76), Expect = 1.8
Identities = 22/83 (26%), Positives = 32/83 (38%), Gaps = 4/83 (4%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTN 61
CG P N +S + VY+C+ G+ L G R C W+ + P C
Sbjct: 2097 CGSPDPIVNGHIS---GDGFSYRDTVVYQCNPGFRLVGTSVRICLQDHKWSGQTPVC-VP 2152
Query: 62 VAFRKPANQSTTVRGGAAANGND 84
+ P N + G+ N ND
Sbjct: 2153 ITCGHPGNPAHGFTNGSEFNLND 2175
Score = 34.7 bits (76), Expect = 1.8
Identities = 16/58 (27%), Positives = 30/58 (51%), Gaps = 5/58 (8%)
Query: 2 CGHPAVPPN-ARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
CG P P + +R+ ++ ++ + C+ G++L G+ +R C L G W+ P C
Sbjct: 2337 CGDPGTPAHGSRLG----DDFKTKSLLRFSCEMGHQLRGSPERTCLLNGSWSGLQPVC 2390
Score = 34.3 bits (75), Expect = 2.4
Identities = 14/38 (36%), Positives = 16/38 (42%)
Query: 431 HGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLF 468
HG + C F LVG TC W G P C+F
Sbjct: 25 HGDTLTFECPAAFELVGERVITCQQNNQWSGNKPSCVF 62
Score = 34.3 bits (75), Expect = 2.4
Identities = 21/61 (34%), Positives = 28/61 (45%), Gaps = 4/61 (6%)
Query: 473 DPPAVSNASVTVNGH-KAGSLASYTCENGHILSGSTSVTCTLGG--AWSGVPPSCKYVNC 529
D P V S + H G +++C G+ L G+T +TC GG WS P C C
Sbjct: 526 DDPGVPAFSRRIGFHFGVGDSLTFSCFLGYRLEGATKLTCLGGGRRVWSAPLPRC-VAEC 584
Query: 530 G 530
G
Sbjct: 585 G 585
Score = 34.3 bits (75), Expect = 2.4
Identities = 18/72 (25%), Positives = 33/72 (45%), Gaps = 3/72 (4%)
Query: 353 CGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKK--DGFWSGAPPSCKYVN 410
C P N ++ +DY VG + ++C G++L+G C+ + W+ P C
Sbjct: 1567 CPDPPPFQNGYMINSDYSVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYPFPRCD-AP 1625
Query: 411 CGGLTPIEDGDV 422
CG ++G +
Sbjct: 1626 CGYNVTSQNGTI 1637
Score = 33.9 bits (74), Expect = 3.2
Identities = 24/87 (27%), Positives = 36/87 (41%), Gaps = 7/87 (8%)
Query: 646 CGKLPTLP-YGTMELLNGTTHL-GSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEE 703
CG P +P YG G++ L G + + C + LVG TC + QWS + P C
Sbjct: 7 CGD-PGIPAYGKR---TGSSFLHGDTLTFECPAAFELVGERVITCQQNNQWSGNKPSC-V 61
Query: 704 IRCSDPIVAEKSIVSVTGNDRSHGHTL 730
C A I+ +G+ +
Sbjct: 62 FSCFFNFTASSGIILSPNYPEEYGNNM 88
Score = 33.9 bits (74), Expect = 3.2
Identities = 16/64 (25%), Positives = 28/64 (43%), Gaps = 1/64 (1%)
Query: 868 GGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLF 927
G ++C + L G + TC QW+G P C+ C +G I+ N +
Sbjct: 26 GDTLTFECPAAFELVGERVITCQQNNQWSGNKPSCV-FSCFFNFTASSGIILSPNYPEEY 84
Query: 928 GSSV 931
G+++
Sbjct: 85 GNNM 88
Score = 33.9 bits (74), Expect = 3.2
Identities = 24/76 (31%), Positives = 31/76 (40%), Gaps = 7/76 (9%)
Query: 845 CPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCIS--KGQWNGTVPVC 902
CPDP + G ++ S S+G ++C GY L GH TC WN P C
Sbjct: 1567 CPDPPP-FQNG---YMINSDYSVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYPFPRC 1622
Query: 903 IPIDCRSPGNIENGKI 918
C +NG I
Sbjct: 1623 -DAPCGYNVTSQNGTI 1637
Score = 33.5 bits (73), Expect = 4.2
Identities = 22/73 (30%), Positives = 36/73 (49%), Gaps = 10/73 (13%)
Query: 717 VSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTC-EDNGQ--W 773
++ T ND R D+R+ G+T V ++C+ GY++ G++ TC + N + W
Sbjct: 867 IAATCNDPGMPQNGTRYGDSREAGDT------VTFQCDPGYQLQGQAKITCVQLNNRFFW 920
Query: 774 SGTTPTCQYVDCG 786
PTC CG
Sbjct: 921 QPDPPTC-IAACG 932
Score = 33.5 bits (73), Expect = 4.2
Identities = 19/60 (31%), Positives = 26/60 (43%), Gaps = 6/60 (10%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTL---RGDWTLEPPFC 58
C P +P N + E AG ++CD GY+L G + C R W +PP C
Sbjct: 871 CNDPGMPQNGTRYGDSRE---AGDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTC 927
Score = 33.1 bits (72), Expect = 5.6
Identities = 21/99 (21%), Positives = 40/99 (40%), Gaps = 8/99 (8%)
Query: 527 VNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGK--WSYDIPSC- 583
V C P I + + + ++ ++C P Y ++G+ L C + W +PSC
Sbjct: 695 VKCEDPGIPNYGYRIRDEGHFTDTVVLYSCNPGYAMHGSNTLTCLSGDRRVWDKPLPSCI 754
Query: 584 -----ELTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAG 617
++ + + S GY +D +H T + G
Sbjct: 755 AECGGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPG 793
Score = 33.1 bits (72), Expect = 5.6
Identities = 18/65 (27%), Positives = 32/65 (49%), Gaps = 5/65 (7%)
Query: 587 SCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVC--QQDGE--WSGDSPTCE 642
+C +P G D+ + STI + C++G+K++ ++ C DG+ W P+C
Sbjct: 1043 ACFDPGNIMNGTRVGTDFKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLPSCN 1102
Query: 643 YIDCG 647
CG
Sbjct: 1103 -APCG 1106
Score = 33.1 bits (72), Expect = 5.6
Identities = 17/68 (25%), Positives = 32/68 (47%), Gaps = 3/68 (4%)
Query: 734 SDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDN--GQWSGTTPTCQYVDCGNPGRI 791
S++ +G+ Y + ++ ++CE GY + G S +C +W+ +P C CG
Sbjct: 1402 SNSIKIGDRYMVNDVLSFQCEPGYTLQGRSHISCMPGTVRRWNYPSPLC-IATCGGTLST 1460
Query: 792 ENGKVTLP 799
G + P
Sbjct: 1461 LGGVILSP 1468
Score = 32.7 bits (71), Expect = 7.4
Identities = 15/57 (26%), Positives = 23/57 (40%), Gaps = 3/57 (5%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
CG P +P + + + + G +EC +EL G R C W+ P C
Sbjct: 7 CGDPGIPAYGKRT---GSSFLHGDTLTFECPAAFELVGERVITCQQNNQWSGNKPSC 60
Score = 32.3 bits (70), Expect = 9.7
Identities = 15/57 (26%), Positives = 26/57 (45%), Gaps = 3/57 (5%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
CG P +P R+S ++ + ++C + L G+ +R C G W+ P C
Sbjct: 2572 CGDPGIPAEGRLS---GKSFTYKSEVFFQCKSPFILVGSSRRVCQADGTWSGIQPTC 2625
>AY243503-1|AAQ89957.1| 3574|Homo sapiens selectin-like protein
protein.
Length = 3574
Score = 313 bits (769), Expect = 2e-84
Identities = 187/624 (29%), Positives = 280/624 (44%), Gaps = 40/624 (6%)
Query: 350 PPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYV 409
P C +P N G Y VG+ + + C EG+ L+G C + G W+ P CK V
Sbjct: 1789 PIKCKAPGNPENGHSSGEIYTVGAEVTFSCQEGYQLMGVTKITCLESGEWNHLIPYCKAV 1848
Query: 410 NCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFD 469
+CG E+G + + T G++ Y C + +TL G+ E +C W P C
Sbjct: 1849 SCGKPAIPENGCIEEL--AFTFGSKVTYRCNKGYTLAGDKESSCLANSSWSHSPPVCEPV 1906
Query: 470 WCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNC 529
C P ++N ++G S ASY+C+ G+ L G + + CT G W PP+C V C
Sbjct: 1907 KCSSPENINNGKYILSGLTYLSTASYSCDTGYSLQGPSIIECTASGIWDRAPPACHLVFC 1966
Query: 530 GTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCP 589
G P K + V+ T+ + +TC+ Y L G + + C DGKWS C SC
Sbjct: 1967 GEPPAIKDA-VITGNNFTFRNTVTYTCKEGYTLAGLDTIECLADGKWSRSDQQCLAVSCD 2025
Query: 590 EPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEW----SGDSPTCEYID 645
EP + E ++C G+ L L+C G+W D P C
Sbjct: 2026 EPPIVDHASPETAHRLFGDIAFYYCSDGYSLADNSQLLCNAQGKWVPPEGQDMPRCIAHF 2085
Query: 646 CGKLPTLPYGTMELLNGTTH-LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDS--SPRCE 702
C K P++ Y +E ++ GSV+ + C + L + C QW+ S S +C
Sbjct: 2086 CEKPPSVSYSILESVSKAKFAAGSVVSFKCMEGFVLNTSAKIECMRGGQWNPSPMSIQCI 2145
Query: 703 EIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGE 762
+RC +P SI+ +G+ G+ Y GA+V Y C KG+ + GE
Sbjct: 2146 PVRCGEP----PSIM--------NGYA---------SGSNYSFGAMVAYSCNKGFYIKGE 2184
Query: 763 SLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGV 822
STCE GQWS PTC V CG P ++ENG + + F YQC+ ++ G
Sbjct: 2185 KKSTCEATGQWSSPIPTCHPVSCGEPPKVENGFLEHTTGRIFESEVR-YQCNPGYKSVGS 2243
Query: 823 IRRMCQENGTWSLEPPI-CKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNL 881
+CQ N W E P+ C + C P I+ G + +G + + C GY L
Sbjct: 2244 PVFVCQANRHWHSESPLMCVPLDCGKP-PPIQNG---FMKGENFEVGSKVQFFCNEGYEL 2299
Query: 882 KGHQTRTCISKGQWN-GTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQ 940
G + TC G+WN + P C+P C P +EN ++V+ +T G V + C +
Sbjct: 2300 VGDSSWTCQKSGKWNKKSNPKCMPAKCPEPPLLEN-QLVLKELTTEVG-VVTFSCKEGHV 2357
Query: 941 RVGPFLRKCLDDGRWSGEEPSCEL 964
GP + KCL +W+ P C++
Sbjct: 2358 LQGPSVLKCLPSQQWNDSFPVCKI 2381
Score = 312 bits (766), Expect = 5e-84
Identities = 187/641 (29%), Positives = 283/641 (44%), Gaps = 41/641 (6%)
Query: 349 LPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSG-APPSCK 407
+P CG P + N + G +++VGS++ + C EG+ L+GD S C+K G W+ + P C
Sbjct: 2263 VPLDCGKPPPIQNGFMKGENFEVGSKVQFFCNEGYELVGDSSWTCQKSGKWNKKSNPKCM 2322
Query: 408 YVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL 467
C P+ + + L + T G +SC+E L G C W+ P C
Sbjct: 2323 PAKCPE-PPLLENQLVLKELTTEVGV-VTFSCKEGHVLQGPSVLKCLPSQQWNDSFPVCK 2380
Query: 468 FDWCPDPPAVS-NASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKY 526
C PP +S + + GS Y+C G L G+++ C G WS P C
Sbjct: 2381 IVLCTPPPLISFGVPIPSSALHFGSTVKYSCVGGFFLRGNSTTLCQPDGTWSSPLPECVP 2440
Query: 527 VNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELT 586
V C P + + G Y S A +TC+P + L G +C +G W P+C+
Sbjct: 2441 VECPQPEEIPNGIIDVQGLA-YLSTALYTCKPGFELVGNTTTLCGENGHWLGGKPTCKAI 2499
Query: 587 SCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDC 646
C +P+ G D + T+ + C G +L G L C + G+W D+P+C I C
Sbjct: 2500 ECLKPKEILNGKFSYTDLHYGQTVTYSCNRGFRLEGPSALTCLETGDWDVDAPSCNAIHC 2559
Query: 647 GKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRC 706
+ G +E G++I YSC +++ G +TC EE WS S P C I C
Sbjct: 2560 DSPQPIENGFVE--GADYSYGAIIIYSCFPGFQVAGHAMQTC-EESGWSSSIPTCMPIDC 2616
Query: 707 SDP-----------------IVAEKSIVSV---TGNDRSHGHTLIRTSDNRDVG-----N 741
P E ++ V T + H + +T +N +
Sbjct: 2617 GLPPHIDFGDCTKLKDDQGYFEQEDDMMEVPYVTPHPPYHLGAVAKTWENTKESPATHSS 2676
Query: 742 TYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSN 801
+ G +V Y C GY+++G + C+++G W+G+ P+C ++C P ENG L
Sbjct: 2677 NFLYGTMVSYTCNPGYELLGNPVLICQEDGTWNGSAPSCISIECDLPTAPENG--FLRFT 2734
Query: 802 ATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVV 861
T G+ Y C L G R+C EN WS P C+ I+C P+ + GS +
Sbjct: 2735 ETSMGSAVQYSCKPGHILAGSDLRLCLENRKWSGASPRCEAISCKKPN-PVMNGS---IK 2790
Query: 862 TSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVIS 921
S + +Y+C+ GY L G + RTC W+ P+CIP+DC SP NG+ +
Sbjct: 2791 GSNYTYLSTLYYECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDCSSPPVSANGQ--VR 2848
Query: 922 NGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
F +EY C + G R CL +G WSG P C
Sbjct: 2849 GDEYTFQKEIEYTCNEGFLLEGARSRVCLANGSWSGATPDC 2889
Score = 297 bits (729), Expect = 1e-79
Identities = 180/617 (29%), Positives = 273/617 (44%), Gaps = 49/617 (7%)
Query: 350 PPTCGSPDKLLNTTILGNDYDV-GSRIVYKCPEGHMLLGDKSRHCKKDGFW-SGAPPSCK 407
P +CG P K+ N + + S + Y+C G+ +G C+ + W S +P C
Sbjct: 2204 PVSCGEPPKVENGFLEHTTGRIFESEVRYQCNPGYKSVGSPVFVCQANRHWHSESPLMCV 2263
Query: 408 YVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEA-PRC 466
++CG PI++G + G++ + C E + LVG+ TC G W+ ++ P+C
Sbjct: 2264 PLDCGKPPPIQNGFMK--GENFEVGSKVQFFCNEGYELVGDSSWTCQKSGKWNKKSNPKC 2321
Query: 467 LFDWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKY 526
+ CP+PP + N V + +++C+ GH+L G + + C W+ P CK
Sbjct: 2322 MPAKCPEPPLLENQLVLKELTTEVGVVTFSCKEGHVLQGPSVLKCLPSQQWNDSFPVCKI 2381
Query: 527 VNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELT 586
V C P + + + +GS +++C ++L G +C DG WS +P C
Sbjct: 2382 VLCTPPPLISFGVPIPSSALHFGSTVKYSCVGGFFLRGNSTTLCQPDGTWSSPLPECVPV 2441
Query: 587 SCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDC 646
CP+PE G ++ ST + C+ G +L+G +C ++G W G PTC+ I+C
Sbjct: 2442 ECPQPEEIPNGIIDVQGLAYLSTALYTCKPGFELVGNTTTLCGENGHWLGGKPTCKAIEC 2501
Query: 647 GKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRC 706
K + G + H G + YSC +RL GP TC E W +P C I C
Sbjct: 2502 LKPKEILNGKFSYTD--LHYGQTVTYSCNRGFRLEGPSALTCLETGDWDVDAPSCNAIHC 2559
Query: 707 SDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLST 766
P E V G Y GA++ Y C G++V G ++ T
Sbjct: 2560 DSPQPIENGFVE---------------------GADYSYGAIIIYSCFPGFQVAGHAMQT 2598
Query: 767 CEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRM 826
CE++G WS + PTC +DCG P I+ G T + Y F Q D+ E+ V
Sbjct: 2599 CEESG-WSSSIPTCMPIDCGLPPHIDFGDCTKLKDDQGY----FEQEDDMMEVPYVTPHP 2653
Query: 827 CQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQT 886
G + KE P+ +S G Y C GY L G+
Sbjct: 2654 PYHLGAVAKTWENTKE----SPATH----------SSNFLYGTMVSYTCNPGYELLGNPV 2699
Query: 887 RTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFL 946
C G WNG+ P CI I+C P ENG + + T GS+V+Y C + G L
Sbjct: 2700 LICQEDGTWNGSAPSCISIECDLPTAPENGFLRFT--ETSMGSAVQYSCKPGHILAGSDL 2757
Query: 947 RKCLDDGRWSGEEPSCE 963
R CL++ +WSG P CE
Sbjct: 2758 RLCLENRKWSGASPRCE 2774
Score = 293 bits (719), Expect = 2e-78
Identities = 185/614 (30%), Positives = 266/614 (43%), Gaps = 36/614 (5%)
Query: 352 TCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNC 411
+C P+ ++N +I G++Y S + Y+C G++L G + R C+ D W P C V+C
Sbjct: 2777 SCKKPNPVMNGSIKGSNYTYLSTLYYECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDC 2836
Query: 412 GGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWC 471
+G V + T Y+C E F L G R C G W G P C+ C
Sbjct: 2837 SSPPVSANGQVR--GDEYTFQKEIEYTCNEGFLLEGARSRVCLANGSWSGATPDCVPVRC 2894
Query: 472 PDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGT 531
PP ++N + ++ C G+IL G+ +TC G W P CK VNCG
Sbjct: 2895 ATPPQLANGVTEGLDYGFMKEVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCKPVNCGP 2954
Query: 532 PTIHKGSFVLING-TTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPE 590
P F NG + +G Q+ C P Y L+G C +G WS PSC C
Sbjct: 2955 PEDLAHGFP--NGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCLPCRCST 3012
Query: 591 PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLP 650
P V G + D+ C G KL+G + C+ DG+WS P CE+ CG LP
Sbjct: 3013 P-VIEYGTVNGTDFDCGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHCEHTSCGSLP 3071
Query: 651 TLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPI 710
+P + ++ +VI YSC + Y + G CTE+ WS P CE + C P
Sbjct: 3072 MIPNAFIS--ETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPLSCGSP- 3128
Query: 711 VAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGES-LSTCED 769
S+ + +H TY + VK RC +GY + ++ TC+
Sbjct: 3129 ---PSVANAVATGEAH---------------TYE--SEVKLRCLEGYTMDTDTDTFTCQK 3168
Query: 770 NGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQE 829
+G+W +C C P I + + + + C E + EGV +CQ
Sbjct: 3169 DGRWFPERISCSPKKCPLPENITH--ILVHGDDFSVNRQVSVSCAEGYTFEGVNISVCQL 3226
Query: 830 NGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTC 889
+GTW EPP E P + ++ VV S + YQCE GY L+G++ R C
Sbjct: 3227 DGTW--EPPFSDESCSPVSCGKPESPEHGFVVGSKYTFESTIIYQCEPGYELEGNRERVC 3284
Query: 890 ISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKC 949
QW+G V +C C + NGK I N +T G +V Y C Y GP C
Sbjct: 3285 QENRQWSGGVAICKETRCETQLEFLNGKADIENRTT--GPNVVYSCNRGYSLEGPSEAHC 3342
Query: 950 LDDGRWSGEEPSCE 963
++G WS P C+
Sbjct: 3343 TENGTWSHPVPLCK 3356
Score = 292 bits (717), Expect = 4e-78
Identities = 180/620 (29%), Positives = 268/620 (43%), Gaps = 50/620 (8%)
Query: 353 CGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCG 412
C P N + + +GS + Y C GH+L G R C ++ WSGA P C+ ++C
Sbjct: 2720 CDLPTAPENGFLRFTETSMGSAVQYSCKPGHILAGSDLRLCLENRKWSGASPRCEAISCK 2779
Query: 413 GLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCP 472
P+ +G + + T+ + Y C + L G RTC D+ WD + P C+ C
Sbjct: 2780 KPNPVMNGSIK--GSNYTYLSTLYYECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDCS 2837
Query: 473 DPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTP 532
PP +N V + + YTC G +L G+ S C G+WSG P C V C TP
Sbjct: 2838 SPPVSANGQVRGDEYTFQKEIEYTCNEGFLLEGARSRVCLANGSWSGATPDCVPVRCATP 2897
Query: 533 TIHKGSFVLINGTT---TYGSIAQ--FTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTS 587
L NG T YG + + F C Y L+GA +L C DG W +IP C+ +
Sbjct: 2898 P------QLANGVTEGLDYGFMKEVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCKPVN 2951
Query: 588 CPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCG 647
C PE + G+ F + I + C G+KL G + C +G WSG SP+C C
Sbjct: 2952 CGPPEDLAHGFPNGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCLPCRC- 3010
Query: 648 KLPTLPYGTMELLNGTT-HLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRC 706
P + YGT +NGT G + C ++L+G TC + QWS P CE C
Sbjct: 3011 STPVIEYGT---VNGTDFDCGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHCEHTSC 3067
Query: 707 SDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLST 766
+ + +S T + + + ++ Y C GY + G S
Sbjct: 3068 GSLPMIPNAFISETSSWKEN---------------------VITYSCRSGYVIQGSSDLI 3106
Query: 767 CEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELE-GVIRR 825
C + G WS P C+ + CG+P + N T A Y + +C E + ++
Sbjct: 3107 CTEKGVWSQPYPVCEPLSCGSPPSVANAVAT--GEAHTYESEVKLRCLEGYTMDTDTDTF 3164
Query: 826 MCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQ 885
CQ++G W E C CP P + + +LV S+ + C GY +G
Sbjct: 3165 TCQKDGRWFPERISCSPKKCPLP----ENITHILVHGDDFSVNRQVSVSCAEGYTFEGVN 3220
Query: 886 TRTCISKGQWNG--TVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVG 943
C G W + C P+ C P + E+G +V S + F S++ Y C Y+ G
Sbjct: 3221 ISVCQLDGTWEPPFSDESCSPVSCGKPESPEHGFVVGSKYT--FESTIIYQCEPGYELEG 3278
Query: 944 PFLRKCLDDGRWSGEEPSCE 963
R C ++ +WSG C+
Sbjct: 3279 NRERVCQENRQWSGGVAICK 3298
Score = 291 bits (714), Expect = 9e-78
Identities = 176/586 (30%), Positives = 255/586 (43%), Gaps = 38/586 (6%)
Query: 372 GSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRTTH 431
G+ + Y C G+ LLG+ C++DG W+G+ PSC + C T E+G + + T+
Sbjct: 2681 GTMVSYTCNPGYELLGNPVLICQEDGTWNGSAPSCISIECDLPTAPENGFLRFTE--TSM 2738
Query: 432 GARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGS 491
G+ YSC+ L G+ R C + W G +PRC C P V N S+ + + S
Sbjct: 2739 GSAVQYSCKPGHILAGSDLRLCLENRKWSGASPRCEAISCKKPNPVMNGSIKGSNYTYLS 2798
Query: 492 LASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTIHKGSFVLINGTTTYGSI 551
Y C+ G++L+G+ TC W P C V+C +P + V T+
Sbjct: 2799 TLYYECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDCSSPPVSANGQVR-GDEYTFQKE 2857
Query: 552 AQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFDYYVHSTIN 611
++TC + L GA VC +G WS P C C P + G E DY +
Sbjct: 2858 IEYTCNEGFLLEGARSRVCLANGSWSGATPDCVPVRCATPPQLANGVTEGLDYGFMKEVT 2917
Query: 612 FHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHL-GSVI 670
FHC G+ L G P L CQ DG W + P C+ ++CG L +G NG + + G I
Sbjct: 2918 FHCHEGYILHGAPKLTCQSDGNWDAEIPLCKPVNCGPPEDLAHG---FPNGFSFIHGGHI 2974
Query: 671 QYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTL 730
QY C Y+L G R C WS SSP C RCS P++ +V G D
Sbjct: 2975 QYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCLPCRCSTPVI---EYGTVNGTD------- 3024
Query: 731 IRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGR 790
D G RI +C KG+K++G S TCE +GQWS P C++ CG+
Sbjct: 3025 ------FDCGKAARI------QCFKGFKLLGLSEITCEADGQWSSGFPHCEHTSCGSLPM 3072
Query: 791 IENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSA 850
I N ++ +++ Y C + ++G +C E G WS P+C+ ++C P +
Sbjct: 3073 IPNAFIS--ETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPLSCGSPPS 3130
Query: 851 QIKAGSGLLVVTSTLSIGGEAHYQCERGYNL-KGHQTRTCISKGQWNGTVPVCIPIDCRS 909
A + + E +C GY + T TC G+W C P C
Sbjct: 3131 VANA----VATGEAHTYESEVKLRCLEGYTMDTDTDTFTCQKDGRWFPERISCSPKKCPL 3186
Query: 910 PGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRW 955
P NI + I++ V C Y G + C DG W
Sbjct: 3187 PENITH--ILVHGDDFSVNRQVSVSCAEGYTFEGVNISVCQLDGTW 3230
Score = 280 bits (687), Expect = 2e-74
Identities = 183/621 (29%), Positives = 269/621 (43%), Gaps = 43/621 (6%)
Query: 349 LPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKY 408
+P C SP N + G++Y I Y C EG +L G +SR C +G WSGA P C
Sbjct: 2832 IPVDCSSPPVSANGQVRGDEYTFQKEIEYTCNEGFLLEGARSRVCLANGSWSGATPDCVP 2891
Query: 409 VNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLF 468
V C + +G +D + C E + L G P+ TC +G WD E P C
Sbjct: 2892 VRCATPPQLANGVTEGLDYGFMK--EVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCKP 2949
Query: 469 DWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVN 528
C P +++ G Y C G+ L G++S C G+WSG PSC
Sbjct: 2950 VNCGPPEDLAHGFPNGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCLPCR 3009
Query: 529 CGTPTIHKGSFVLINGTT-TYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTS 587
C TP I G+ +NGT G A+ C + L G E+ C DG+WS P CE TS
Sbjct: 3010 CSTPVIEYGT---VNGTDFDCGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHCEHTS 3066
Query: 588 CPE-PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDC 646
C P +P+ ++ + + I + C +G+ + G +L+C + G WS P CE + C
Sbjct: 3067 CGSLPMIPN-AFISETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPLSC 3125
Query: 647 GKLPTLPYGTMELLNGTTH-LGSVIQYSCTTNYRL-VGPVRRTCTEEFQWSDSSPRCEEI 704
G P++ + G H S ++ C Y + TC ++ +W C
Sbjct: 3126 GSPPSV---ANAVATGEAHTYESEVKLRCLEGYTMDTDTDTFTCQKDGRWFPERISCSPK 3182
Query: 705 RCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESL 764
+C P ++T H L+ G+ + + V C +GY G ++
Sbjct: 3183 KCPLP-------ENIT-------HILVH-------GDDFSVNRQVSVSCAEGYTFEGVNI 3221
Query: 765 STCEDNGQWSG--TTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGV 822
S C+ +G W + +C V CG P E+G V + S TF +T YQC+ +ELEG
Sbjct: 3222 SVCQLDGTWEPPFSDESCSPVSCGKPESPEHGFV-VGSKYTF-ESTIIYQCEPGYELEGN 3279
Query: 823 IRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLK 882
R+CQEN WS ICKE C Q++ +G + + + G Y C RGY+L+
Sbjct: 3280 RERVCQENRQWSGGVAICKETRC---ETQLEFLNGKADIENR-TTGPNVVYSCNRGYSLE 3335
Query: 883 GHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRV 942
G C G W+ VP+C P C P I + +S +V C +
Sbjct: 3336 GPSEAHCTENGTWSHPVPLCKPNPCPVPFVIPENAL-LSEKEFYVDQNVSIKCREGFLLQ 3394
Query: 943 GPFLRKCLDDGRWSGEEPSCE 963
G + D W+ CE
Sbjct: 3395 GHGIITYNPDETWTQTSAKCE 3415
Score = 266 bits (653), Expect = 2e-70
Identities = 169/600 (28%), Positives = 259/600 (43%), Gaps = 40/600 (6%)
Query: 372 GSRIVYKCPEGHMLLGDKSRHCKKDGFW---SGAP-PSCKYVNCGGLTPIEDGDVALIDN 427
G Y C +G+ L + C G W G P C C + + +
Sbjct: 2043 GDIAFYYCSDGYSLADNSQLLCNAQGKWVPPEGQDMPRCIAHFCEKPPSVSYSILESVSK 2102
Query: 428 -RTTHGARALYSCRENFTLVGNPERTCGDEGIWDGE--APRCLFDWCPDPPAVSNASVTV 484
+ G+ + C E F L + + C G W+ + +C+ C +PP++ N +
Sbjct: 2103 AKFAAGSVVSFKCMEGFVLNTSAKIECMRGGQWNPSPMSIQCIPVRCGEPPSIMNGYASG 2162
Query: 485 NGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTIHKGSFVLING 544
+ + G++ +Y+C G + G TC G WS P+C V+CG P + F+
Sbjct: 2163 SNYSFGAMVAYSCNKGFYIKGEKKSTCEATGQWSSPIPTCHPVSCGEPPKVENGFLEHTT 2222
Query: 545 TTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIP-SCELTSCPEPEVPSGGYMEAFD 603
+ S ++ C P Y G+ VC + W + P C C +P G+M+ +
Sbjct: 2223 GRIFESEVRYQCNPGYKSVGSPVFVCQANRHWHSESPLMCVPLDCGKPPPIQNGFMKGEN 2282
Query: 604 YYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDS-PTCEYIDCGKLPTLPYGTMELLNG 662
+ V S + F C G++L+G+ + CQ+ G+W+ S P C C + P L + L
Sbjct: 2283 FEVGSKVQFFCNEGYELVGDSSWTCQKSGKWNKKSNPKCMPAKCPEPPLLE-NQLVLKEL 2341
Query: 663 TTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGN 722
TT +G V+ +SC + L GP C QW+DS P C+ + C+ P +
Sbjct: 2342 TTEVG-VVTFSCKEGHVLQGPSVLKCLPSQQWNDSFPVCKIVLCTPPPLI---------- 2390
Query: 723 DRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQY 782
S G + + G+ VKY C G+ + G S + C+ +G WS P C
Sbjct: 2391 --SFGVPI--------PSSALHFGSTVKYSCVGGFFLRGNSTTLCQPDGTWSSPLPECVP 2440
Query: 783 VDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKE 842
V+C P I NG + + A Y +TA Y C +EL G +C ENG W P CK
Sbjct: 2441 VECPQPEEIPNGIIDVQGLA--YLSTALYTCKPGFELVGNTTTLCGENGHWLGGKPTCKA 2498
Query: 843 ITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVC 902
I C P + +G T L G Y C RG+ L+G TC+ G W+ P C
Sbjct: 2499 IECLKPKEIL---NGKFSYTD-LHYGQTVTYSCNRGFRLEGPSALTCLETGDWDVDAPSC 2554
Query: 903 IPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
I C SP IENG + +G+ + Y C +Q G ++ C + G WS P+C
Sbjct: 2555 NAIHCDSPQPIENG--FVEGADYSYGAIIIYSCFPGFQVAGHAMQTCEESG-WSSSIPTC 2611
Score = 266 bits (652), Expect = 3e-70
Identities = 174/621 (28%), Positives = 251/621 (40%), Gaps = 46/621 (7%)
Query: 349 LPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKY 408
+P C +P +L N G DY + + C EG++L G C+ DG W P CK
Sbjct: 2890 VPVRCATPPQLANGVTEGLDYGFMKEVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCKP 2949
Query: 409 VNCGGLTPIEDGDVALIDNRT-THGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL 467
VNCG P ED + + HG Y C + L GN R C G W G +P CL
Sbjct: 2950 VNCG---PPEDLAHGFPNGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCL 3006
Query: 468 FDWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYV 527
C P + +V G A C G L G + +TC G WS P C++
Sbjct: 3007 PCRC-STPVIEYGTVNGTDFDCGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHCEHT 3065
Query: 528 NCGTPTIHKGSFVLINGTTTYG-SIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELT 586
+CG+ + +F I+ T+++ ++ ++C Y + G+ +L+C G WS P CE
Sbjct: 3066 SCGSLPMIPNAF--ISETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPL 3123
Query: 587 SCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPN-LVCQQDGEWSGDSPTCEYID 645
SC P + + S + C G+ + + + CQ+DG W + +C
Sbjct: 3124 SCGSPPSVANAVATGEAHTYESEVKLRCLEGYTMDTDTDTFTCQKDGRWFPERISCSPKK 3183
Query: 646 CGKLPTLPYGTMELLNGTTH-LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSD--SSPRCE 702
C P T L++G + + SC Y G C + W S C
Sbjct: 3184 C---PLPENITHILVHGDDFSVNRQVSVSCAEGYTFEGVNISVCQLDGTWEPPFSDESCS 3240
Query: 703 EIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGE 762
+ C P E HG VG+ Y + + Y+CE GY++ G
Sbjct: 3241 PVSCGKPESPE------------HGFV---------VGSKYTFESTIIYQCEPGYELEGN 3279
Query: 763 SLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGV 822
C++N QWSG C+ C NGK + + T G Y C+ + LEG
Sbjct: 3280 RERVCQENRQWSGGVAICKETRCETQLEFLNGKADIENRTT--GPNVVYSCNRGYSLEGP 3337
Query: 823 IRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLK 882
C ENGTWS P+CK CP P L+ + +C G+ L+
Sbjct: 3338 SEAHCTENGTWSHPVPLCKPNPCPVP---FVIPENALLSEKEFYVDQNVSIKCREGFLLQ 3394
Query: 883 GHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRV 942
GH T W T C I C P ++EN + +G + Y C S Y
Sbjct: 3395 GHGIITYNPDETWTQTSAKCEKISCGPPAHVENA--IARGVHYQYGDMITYSCYSGYMLE 3452
Query: 943 GPFLRK-CLDDGRWSGEEPSC 962
G FLR CL++G W+ P C
Sbjct: 3453 G-FLRSVCLENGTWT-SPPIC 3471
Score = 266 bits (651), Expect = 4e-70
Identities = 165/537 (30%), Positives = 232/537 (43%), Gaps = 42/537 (7%)
Query: 431 HGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAG 490
+G Y+C + L+GNP C ++G W+G AP C+ C P A N + G
Sbjct: 2680 YGTMVSYTCNPGYELLGNPVLICQEDGTWNGSAPSCISIECDLPTAPENGFLRFTETSMG 2739
Query: 491 SLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPT-IHKGSFVLINGTT-TY 548
S Y+C+ GHIL+GS C WSG P C+ ++C P + GS I G+ TY
Sbjct: 2740 SAVQYSCKPGHILAGSDLRLCLENRKWSGASPRCEAISCKKPNPVMNGS---IKGSNYTY 2796
Query: 549 GSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFDYYVHS 608
S + C+P Y LNG E C D W D P C C P V + G + +Y
Sbjct: 2797 LSTLYYECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDCSSPPVSANGQVRGDEYTFQK 2856
Query: 609 TINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGS 668
I + C G L G + VC +G WSG +P C + C P L G E L+
Sbjct: 2857 EIEYTCNEGFLLEGARSRVCLANGSWSGATPDCVPVRCATPPQLANGVTEGLD--YGFMK 2914
Query: 669 VIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGH 728
+ + C Y L G + TC + W P C+ + C P D +HG
Sbjct: 2915 EVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCKPVNCGPP------------EDLAHGF 2962
Query: 729 TLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNP 788
G ++ G ++Y+C GYK+ G S C NG WSG++P+C C P
Sbjct: 2963 ---------PNGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCLPCRCSTP 3013
Query: 789 GRIENGKVTLPSNATFY--GATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCP 846
IE G V N T + G A QC + ++L G+ C+ +G WS P C+ +C
Sbjct: 3014 -VIEYGTV----NGTDFDCGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHCEHTSC- 3067
Query: 847 DPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPID 906
+ + + TS+ Y C GY ++G C KG W+ PVC P+
Sbjct: 3068 --GSLPMIPNAFISETSSWK-ENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPLS 3124
Query: 907 CRSPGNIENGKIVISNGSTLFGSSVEYYCLSQY-QRVGPFLRKCLDDGRWSGEEPSC 962
C SP ++ N V + + + S V+ CL Y C DGRW E SC
Sbjct: 3125 CGSPPSVANA--VATGEAHTYESEVKLRCLEGYTMDTDTDTFTCQKDGRWFPERISC 3179
Score = 248 bits (607), Expect = 8e-65
Identities = 145/505 (28%), Positives = 219/505 (43%), Gaps = 31/505 (6%)
Query: 347 QYLPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSC 406
Q +P CG P ++N G++Y G+ + Y C +G + G+K C+ G WS P+C
Sbjct: 2143 QCIPVRCGEPPSIMNGYASGSNYSFGAMVAYSCNKGFYIKGEKKSTCEATGQWSSPIPTC 2202
Query: 407 KYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAP-R 465
V+CG +E+G + R + Y C + VG+P C W E+P
Sbjct: 2203 HPVSCGEPPKVENGFLEHTTGRIFE-SEVRYQCNPGYKSVGSPVFVCQANRHWHSESPLM 2261
Query: 466 CLFDWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVP-PSC 524
C+ C PP + N + + GS + C G+ L G +S TC G W+ P C
Sbjct: 2262 CVPLDCGKPPPIQNGFMKGENFEVGSKVQFFCNEGYELVGDSSWTCQKSGKWNKKSNPKC 2321
Query: 525 KYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCE 584
C P + + VL TT G + F+C+ + L G L C +W+ P C+
Sbjct: 2322 MPAKCPEPPLLENQLVLKELTTEVG-VVTFSCKEGHVLQGPSVLKCLPSQQWNDSFPVCK 2380
Query: 585 LTSC-PEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEY 643
+ C P P + G + + + ST+ + C G L G +CQ DG WS P C
Sbjct: 2381 IVLCTPPPLISFGVPIPSSALHFGSTVKYSCVGGFFLRGNSTTLCQPDGTWSSPLPECVP 2440
Query: 644 IDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEE 703
++C + +P G ++ + G +L + + Y+C + LVG C E W P C+
Sbjct: 2441 VECPQPEEIPNGIID-VQGLAYLSTAL-YTCKPGFELVGNTTTLCGENGHWLGGKPTCKA 2498
Query: 704 IRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGES 763
I C P S T D +G T V Y C +G+++ G S
Sbjct: 2499 IECLKPKEILNGKFSYT--DLHYGQT-------------------VTYSCNRGFRLEGPS 2537
Query: 764 LSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVI 823
TC + G W P+C + C +P IENG V + YGA Y C +++ G
Sbjct: 2538 ALTCLETGDWDVDAPSCNAIHCDSPQPIENGFVEGADYS--YGAIIIYSCFPGFQVAGHA 2595
Query: 824 RRMCQENGTWSLEPPICKEITCPDP 848
+ C+E+G WS P C I C P
Sbjct: 2596 MQTCEESG-WSSSIPTCMPIDCGLP 2619
Score = 241 bits (589), Expect = 1e-62
Identities = 168/620 (27%), Positives = 259/620 (41%), Gaps = 63/620 (10%)
Query: 352 TCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVN- 410
+CG P L N +D+ GS + Y+C G+ LLGD C +G W+G PSC V+
Sbjct: 1692 SCGVPPPLENGFHSADDFYAGSTVTYQCNNGYYLLGDSRMFCTDNGSWNGVSPSCLDVDE 1751
Query: 411 CG-GLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFD 469
C G E +D + SC ++T G + C E +C
Sbjct: 1752 CAVGSDCSEHASCLNVD------GSYICSCVPSYTGDG---KNC-------AEPIKCK-- 1793
Query: 470 WCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNC 529
P P ++S + + G+ +++C+ G+ L G T +TC G W+ + P CK V+C
Sbjct: 1794 -APGNPENGHSSGEI--YTVGAEVTFSCQEGYQLMGVTKITCLESGEWNHLIPYCKAVSC 1850
Query: 530 GTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCP 589
G P I + + T+GS + C Y L G +E C + WS+ P CE C
Sbjct: 1851 GKPAIPENG-CIEELAFTFGSKVTYRCNKGYTLAGDKESSCLANSSWSHSPPVCEPVKCS 1909
Query: 590 EPE-VPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGK 648
PE + +G Y+ + Y+ ST ++ C+ G+ L G + C G W P C + CG+
Sbjct: 1910 SPENINNGKYILSGLTYL-STASYSCDTGYSLQGPSIIECTASGIWDRAPPACHLVFCGE 1968
Query: 649 LPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSD 708
P + + N T + + Y+C Y L G C + +WS S +C + C +
Sbjct: 1969 PPAIKDAVITGNNFT--FRNTVTYTCKEGYTLAGLDTIECLADGKWSRSDQQCLAVSCDE 2026
Query: 709 PIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCE 768
P + + + H L G + Y C GY + S C
Sbjct: 2027 PPIVDHA-------SPETAHRL--------------FGDIAFYYCSDGYSLADNSQLLCN 2065
Query: 769 DNGQW----SGTTPTCQYVDCGNPGRIENGKVTLPSNATF-YGATAFYQCDENWELEGVI 823
G+W P C C P + + S A F G+ ++C E + L
Sbjct: 2066 AQGKWVPPEGQDMPRCIAHFCEKPPSVSYSILESVSKAKFAAGSVVSFKCMEGFVLNTSA 2125
Query: 824 RRMCQENGTWSLEPPI--CKEITCPDPSAQIKA-GSGLLVVTSTLSIGGEAHYQCERGYN 880
+ C G W+ P C + C +P + + SG S S G Y C +G+
Sbjct: 2126 KIECMRGGQWNPSPMSIQCIPVRCGEPPSIMNGYASG-----SNYSFGAMVAYSCNKGFY 2180
Query: 881 LKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQ 940
+KG + TC + GQW+ +P C P+ C P +ENG + + G +F S V Y C Y+
Sbjct: 2181 IKGEKKSTCEATGQWSSPIPTCHPVSCGEPPKVENGFLEHTTG-RIFESEVRYQCNPGYK 2239
Query: 941 RVGPFLRKCLDDGRWSGEEP 960
VG + C + W E P
Sbjct: 2240 SVGSPVFVCQANRHWHSESP 2259
Score = 235 bits (574), Expect = 8e-61
Identities = 159/605 (26%), Positives = 253/605 (41%), Gaps = 62/605 (10%)
Query: 368 DYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDN 427
D GS++ C G L+G+ ++C G W+ P C+ ++CG P+E+G + D
Sbjct: 1650 DLKPGSKVNLFCDPGFQLVGNPVQYCLNQGQWTQPLPHCERISCGVPPPLENGFHSADDF 1709
Query: 428 RTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL-FDWCPDPPAVSNASVTVNG 486
G+ Y C + L+G+ C D G W+G +P CL D C
Sbjct: 1710 YA--GSTVTYQCNNGYYLLGDSRMFCTDNGSWNGVSPSCLDVDEC--------------- 1752
Query: 487 HKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSC-KYVNCGTPTIHKGSFVLINGT 545
++ S E+ L+ S C+ +++G +C + + C P +
Sbjct: 1753 ----AVGSDCSEHASCLNVDGSYICSCVPSYTGDGKNCAEPIKCKAPGNPENGH-SSGEI 1807
Query: 546 TTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFDYY 605
T G+ F+C+ Y L G ++ C G+W++ IP C+ SC +P +P G +E +
Sbjct: 1808 YTVGAEVTFSCQEGYQLMGVTKITCLESGEWNHLIPYCKAVSCGKPAIPENGCIEELAFT 1867
Query: 606 VHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTH 665
S + + C G+ L G+ C + WS P CE + C + G +L+G T+
Sbjct: 1868 FGSKVTYRCNKGYTLAGDKESSCLANSSWSHSPPVCEPVKCSSPENINNGKY-ILSGLTY 1926
Query: 666 LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRS 725
L S YSC T Y L GP CT W + P C + C +P + ++++
Sbjct: 1927 L-STASYSCDTGYSLQGPSIIECTASGIWDRAPPACHLVFCGEPPAIKDAVIT------- 1978
Query: 726 HGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDC 785
GN + V Y C++GY + G C +G+WS + C V C
Sbjct: 1979 --------------GNNFTFRNTVTYTCKEGYTLAGLDTIECLADGKWSRSDQQCLAVSC 2024
Query: 786 GNPGRIENGKVTLPSNA-TFYGATAFYQCDENWELEGVIRRMCQENGTW----SLEPPIC 840
P +++ P A +G AFY C + + L + +C G W + P C
Sbjct: 2025 DEPPIVDHAS---PETAHRLFGDIAFYYCSDGYSLADNSQLLCNAQGKWVPPEGQDMPRC 2081
Query: 841 KEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVP 900
C P + + V + + G ++C G+ L C+ GQWN + P
Sbjct: 2082 IAHFCEKPPS-VSYSILESVSKAKFAAGSVVSFKCMEGFVLNTSAKIECMRGGQWNPS-P 2139
Query: 901 V---CIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSG 957
+ CIP+ C P +I NG SN S FG+ V Y C + G C G+WS
Sbjct: 2140 MSIQCIPVRCGEPPSIMNGYASGSNYS--FGAMVAYSCNKGFYIKGEKKSTCEATGQWSS 2197
Query: 958 EEPSC 962
P+C
Sbjct: 2198 PIPTC 2202
Score = 158 bits (383), Expect = 1e-37
Identities = 122/483 (25%), Positives = 189/483 (39%), Gaps = 49/483 (10%)
Query: 352 TCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNC 411
+CGS + N I + I Y C G+++ G C + G WS P C+ ++C
Sbjct: 3066 SCGSLPMIPNAFISETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPLSC 3125
Query: 412 GGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPER-TCGDEGIWDGEAPRCLFDW 470
G +P + T+ + C E +T+ + + TC +G W E C
Sbjct: 3126 G--SPPSVANAVATGEAHTYESEVKLRCLEGYTMDTDTDTFTCQKDGRWFPERISCSPKK 3183
Query: 471 CPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPP----SCKY 526
CP P +++ V + S +C G+ G C L G W PP SC
Sbjct: 3184 CPLPENITHILVHGDDFSVNRQVSVSCAEGYTFEGVNISVCQLDGTWE--PPFSDESCSP 3241
Query: 527 VNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELT 586
V+CG P + FV + T+ S + CEP Y L G E VC + +WS + C+ T
Sbjct: 3242 VSCGKPESPEHGFV-VGSKYTFESTIIYQCEPGYELEGNRERVCQENRQWSGGVAICKET 3300
Query: 587 SCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDC 646
C G + + + + C G+ L G C ++G WS P C+ C
Sbjct: 3301 RCETQLEFLNGKADIENRTTGPNVVYSCNRGYSLEGPSEAHCTENGTWSHPVPLCKPNPC 3360
Query: 647 GKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRC 706
+P + L ++ + C + L G T + W+ +S +CE+I C
Sbjct: 3361 PVPFVIPENAL-LSEKEFYVDQNVSIKCREGFLLQGHGIITYNPDETWTQTSAKCEKISC 3419
Query: 707 SDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLST 766
P E +I G Y+ G ++ Y C GY + G S
Sbjct: 3420 GPPAHVENAIAR---------------------GVHYQYGDMITYSCYSGYMLEGFLRSV 3458
Query: 767 CEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRM 826
C +NG W+ + P C+ V C P +NG + NA C E W + R+
Sbjct: 3459 CLENGTWT-SPPICRAV-CRFP--CQNGGICQRPNAC--------SCPEGW-----MGRL 3501
Query: 827 CQE 829
C+E
Sbjct: 3502 CEE 3504
Score = 145 bits (352), Expect = 7e-34
Identities = 101/369 (27%), Positives = 143/369 (38%), Gaps = 13/369 (3%)
Query: 345 ICQYLPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRH-CKKDGFWSGAP 403
+C+ P +CGSP + N G + S + +C EG+ + D C+KDG W
Sbjct: 3119 VCE--PLSCGSPPSVANAVATGEAHTYESEVKLRCLEGYTMDTDTDTFTCQKDGRWFPER 3176
Query: 404 PSCKYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDG-- 461
SC C P + + + + + SC E +T G C +G W+
Sbjct: 3177 ISCSPKKCP--LPENITHILVHGDDFSVNRQVSVSCAEGYTFEGVNISVCQLDGTWEPPF 3234
Query: 462 EAPRCLFDWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVP 521
C C P + + V + + S Y CE G+ L G+ C WSG
Sbjct: 3235 SDESCSPVSCGKPESPEHGFVVGSKYTFESTIIYQCEPGYELEGNRERVCQENRQWSGGV 3294
Query: 522 PSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIP 581
CK C T I TT G ++C Y L G E C +G WS+ +P
Sbjct: 3295 AICKETRCETQLEFLNGKADIENRTT-GPNVVYSCNRGYSLEGPSEAHCTENGTWSHPVP 3353
Query: 582 SCELTSCPEPEV-PSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPT 640
C+ CP P V P + ++YV ++ C G L G + D W+ S
Sbjct: 3354 LCKPNPCPVPFVIPENALLSEKEFYVDQNVSIKCREGFLLQGHGIITYNPDETWTQTSAK 3413
Query: 641 CEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPR 700
CE I CG P G +I YSC + Y L G +R C E W+ S P
Sbjct: 3414 CEKISCG--PPAHVENAIARGVHYQYGDMITYSCYSGYMLEGFLRSVCLENGTWT-SPPI 3470
Query: 701 CEEIRCSDP 709
C + C P
Sbjct: 3471 CRAV-CRFP 3478
Score = 129 bits (311), Expect = 6e-29
Identities = 100/347 (28%), Positives = 147/347 (42%), Gaps = 38/347 (10%)
Query: 644 IDCGKLPTLPYGTMELLNGTTHL--GSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRC 701
I C P L L + L GS + C ++LVG + C + QW+ P C
Sbjct: 1629 IFCSDCPRLGGSVPHLRTASEDLKPGSKVNLFCDPGFQLVGNPVQYCLNQGQWTQPLPHC 1688
Query: 702 EEIRCSDPIVAEKSIVSV----TGNDRSH----GHTLIRTSDN--RDVG--NTYRIGALV 749
E I C P E S G+ ++ G+ L+ S D G N L
Sbjct: 1689 ERISCGVPPPLENGFHSADDFYAGSTVTYQCNNGYYLLGDSRMFCTDNGSWNGVSPSCLD 1748
Query: 750 KYRCEKG---------YKVIGESLSTCEDNGQWSGTTPTC-QYVDCGNPGRIENGKVTLP 799
C G V G + +C + ++G C + + C PG ENG
Sbjct: 1749 VDECAVGSDCSEHASCLNVDGSYICSCVPS--YTGDGKNCAEPIKCKAPGNPENGH---- 1802
Query: 800 SNATFY--GATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSG 857
S+ Y GA + C E ++L GV + C E+G W+ P CK ++C P+
Sbjct: 1803 SSGEIYTVGAEVTFSCQEGYQLMGVTKITCLESGEWNHLIPYCKAVSCGKPAIPENGCIE 1862
Query: 858 LLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGK 917
L T G + Y+C +GY L G + +C++ W+ + PVC P+ C SP NI NGK
Sbjct: 1863 ELAFT----FGSKVTYRCNKGYTLAGDKESSCLANSSWSHSPPVCEPVKCSSPENINNGK 1918
Query: 918 IVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCEL 964
++S G T + S+ Y C + Y GP + +C G W P+C L
Sbjct: 1919 YILS-GLT-YLSTASYSCDTGYSLQGPSIIECTASGIWDRAPPACHL 1963
Score = 76.6 bits (180), Expect = 5e-13
Identities = 44/163 (26%), Positives = 67/163 (41%), Gaps = 6/163 (3%)
Query: 752 RCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFY 811
RC G+ ++G S+ C NG WSG C+ C + + ++G ++ + Y T
Sbjct: 405 RCHPGFDLVGSSIILCLPNGLWSGLESYCRVRTCPHLRQPKHGHISCSTREMLYKTTCLV 464
Query: 812 QCDENWELEGVIRRMCQENGTWSLEPPICKEITCPD---PSAQIKAGSGLLVVTSTLSIG 868
CDE + LEG + CQ N W P C E C P I + G
Sbjct: 465 ACDEGYRLEGSDKLTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISPHN--CGKQPAKFG 522
Query: 869 GEAHYQCERGYNLKG-HQTRTCISKGQWNGTVPVCIPIDCRSP 910
+ C +G+ L G + C + G+WN V + D +P
Sbjct: 523 TICYVSCRQGFILSGVKEMLRCTTSGKWNVGVQAAVCKDVEAP 565
Score = 75.4 bits (177), Expect = 1e-12
Identities = 47/196 (23%), Positives = 76/196 (38%), Gaps = 7/196 (3%)
Query: 405 SCKYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAP 464
+C+ V+C L P E+G A C F LVG+ C G+W G
Sbjct: 372 TCELVHCPALKPPENGYFIQNTCNNHFNAACGVRCHPGFDLVGSSIILCLPNGLWSGLES 431
Query: 465 RCLFDWCPD--PPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPP 522
C CP P + S + + C+ G+ L GS +TC W G P
Sbjct: 432 YCRVRTCPHLRQPKHGHISCSTREMLYKTTCLVACDEGYRLEGSDKLTCQGNSQWDGPEP 491
Query: 523 SCKYVNCGTPTIHKGSFVLING----TTTYGSIAQFTCEPDYWLNGAEELV-CNRDGKWS 577
C +C T + K + + +G+I +C + L+G +E++ C GKW+
Sbjct: 492 RCVERHCSTFQMPKDVIISPHNCGKQPAKFGTICYVSCRQGFILSGVKEMLRCTTSGKWN 551
Query: 578 YDIPSCELTSCPEPEV 593
+ + P++
Sbjct: 552 VGVQAAVCKDVEAPQI 567
Score = 73.3 bits (172), Expect = 4e-12
Identities = 46/158 (29%), Positives = 67/158 (42%), Gaps = 8/158 (5%)
Query: 378 KCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRTTHGARALY 437
+C G L+G C +G WSG C+ C L + G ++ + L
Sbjct: 405 RCHPGFDLVGSSIILCLPNGLWSGLESYCRVRTCPHLRQPKHGHISCSTREMLYKTTCLV 464
Query: 438 SCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWC-----PDPPAVSNASVTVNGHKAGSL 492
+C E + L G+ + TC WDG PRC+ C P +S + K G++
Sbjct: 465 ACDEGYRLEGSDKLTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISPHNCGKQPAKFGTI 524
Query: 493 ASYTCENGHILSG-STSVTCTLGGAWS-GVPPS-CKYV 527
+C G ILSG + CT G W+ GV + CK V
Sbjct: 525 CYVSCRQGFILSGVKEMLRCTTSGKWNVGVQAAVCKDV 562
Score = 72.1 bits (169), Expect = 1e-11
Identities = 39/122 (31%), Positives = 57/122 (46%), Gaps = 2/122 (1%)
Query: 841 KEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVP 900
K I C D + L + L G + + C+ G+ L G+ + C+++GQW +P
Sbjct: 1627 KSIFCSDCPRLGGSVPHLRTASEDLKPGSKVNLFCDPGFQLVGNPVQYCLNQGQWTQPLP 1686
Query: 901 VCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEP 960
C I C P +ENG S GS+V Y C + Y +G C D+G W+G P
Sbjct: 1687 HCERISCGVPPPLENG--FHSADDFYAGSTVTYQCNNGYYLLGDSRMFCTDNGSWNGVSP 1744
Query: 961 SC 962
SC
Sbjct: 1745 SC 1746
Score = 70.9 bits (166), Expect = 2e-11
Identities = 43/155 (27%), Positives = 64/155 (41%), Gaps = 4/155 (2%)
Query: 566 EELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYM--EAFDYYVHSTINFHCEAGHKLIGE 623
E+ VC R+G + +CEL CP + P GY + + ++ C G L+G
Sbjct: 358 EDCVC-REG-YRASGQTCELVHCPALKPPENGYFIQNTCNNHFNAACGVRCHPGFDLVGS 415
Query: 624 PNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGP 683
++C +G WSG C C L +G + + +C YRL G
Sbjct: 416 SIILCLPNGLWSGLESYCRVRTCPHLRQPKHGHISCSTREMLYKTTCLVACDEGYRLEGS 475
Query: 684 VRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVS 718
+ TC QW PRC E CS + + I+S
Sbjct: 476 DKLTCQGNSQWDGPEPRCVERHCSTFQMPKDVIIS 510
Score = 62.1 bits (144), Expect = 1e-08
Identities = 47/206 (22%), Positives = 78/206 (37%), Gaps = 8/206 (3%)
Query: 498 ENGHILSGSTSVT-CTLGGAWSGVPPSCKYVNC-GTPTIHKGSFVLINGTTTYGSIAQFT 555
EN GSTS C + +C+ V+C G F+ + +
Sbjct: 346 ENHTSPPGSTSPEDCVCREGYRASGQTCELVHCPALKPPENGYFIQNTCNNHFNAACGVR 405
Query: 556 CEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAF--DYYVHSTINFH 613
C P + L G+ ++C +G WS C + +CP P G++ + +T
Sbjct: 406 CHPGFDLVGSSIILCLPNGLWSGLESYCRVRTCPHLRQPKHGHISCSTREMLYKTTCLVA 465
Query: 614 CEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCG--KLP-TLPYGTMELLNGTTHLGSVI 670
C+ G++L G L CQ + +W G P C C ++P + G++
Sbjct: 466 CDEGYRLEGSDKLTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISPHNCGKQPAKFGTIC 525
Query: 671 QYSCTTNYRLVGPVRR-TCTEEFQWS 695
SC + L G CT +W+
Sbjct: 526 YVSCRQGFILSGVKEMLRCTTSGKWN 551
Score = 59.7 bits (138), Expect = 6e-08
Identities = 48/194 (24%), Positives = 73/194 (37%), Gaps = 8/194 (4%)
Query: 767 CEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRM 826
C + + SG T C+ V C ENG + + A +C ++L G +
Sbjct: 362 CREGYRASGQT--CELVHCPALKPPENGYFIQNTCNNHFNAACGVRCHPGFDLVGSSIIL 419
Query: 827 CQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQT 886
C NG WS C+ TCP Q K G + T + C+ GY L+G
Sbjct: 420 CLPNGLWSGLESYCRVRTCPH-LRQPKHGH-ISCSTREMLYKTTCLVACDEGYRLEGSDK 477
Query: 887 RTCISKGQWNGTVPVCIPIDC---RSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVG 943
TC QW+G P C+ C + P ++ FG+ C + G
Sbjct: 478 LTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISPHNCGKQPAKFGTICYVSCRQGFILSG 537
Query: 944 -PFLRKCLDDGRWS 956
+ +C G+W+
Sbjct: 538 VKEMLRCTTSGKWN 551
Score = 46.0 bits (104), Expect = 7e-04
Identities = 19/57 (33%), Positives = 27/57 (47%), Gaps = 3/57 (5%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
CG PA+P N + E G+ Y C++GY L G ++ C W+ PP C
Sbjct: 1850 CGKPAIPENGCIE---ELAFTFGSKVTYRCNKGYTLAGDKESSCLANSSWSHSPPVC 1903
Score = 45.2 bits (102), Expect = 0.001
Identities = 23/89 (25%), Positives = 36/89 (40%)
Query: 874 QCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEY 933
+C G++L G C+ G W+G C C ++G I S L+ ++
Sbjct: 405 RCHPGFDLVGSSIILCLPNGLWSGLESYCRVRTCPHLRQPKHGHISCSTREMLYKTTCLV 464
Query: 934 YCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
C Y+ G C + +W G EP C
Sbjct: 465 ACDEGYRLEGSDKLTCQGNSQWDGPEPRC 493
Score = 40.7 bits (91), Expect = 0.028
Identities = 17/43 (39%), Positives = 20/43 (46%)
Query: 19 ENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTN 61
EN G VY C+ GY L G + CT G W+ P C N
Sbjct: 3316 ENRTTGPNVVYSCNRGYSLEGPSEAHCTENGTWSHPVPLCKPN 3358
Score = 40.3 bits (90), Expect = 0.037
Identities = 17/52 (32%), Positives = 24/52 (46%)
Query: 7 VPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
VPP + ++ AG+ Y+C+ GY L G + CT G W P C
Sbjct: 1695 VPPPLENGFHSADDFYAGSTVTYQCNNGYYLLGDSRMFCTDNGSWNGVSPSC 1746
Score = 40.3 bits (90), Expect = 0.037
Identities = 23/67 (34%), Positives = 30/67 (44%), Gaps = 4/67 (5%)
Query: 14 SIPNEENIVAG----TIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTNVAFRKPAN 69
+I N + I++G + A Y CD GY L G ECT G W PP C PA
Sbjct: 1913 NINNGKYILSGLTYLSTASYSCDTGYSLQGPSIIECTASGIWDRAPPACHLVFCGEPPAI 1972
Query: 70 QSTTVRG 76
+ + G
Sbjct: 1973 KDAVITG 1979
Score = 39.1 bits (87), Expect = 0.085
Identities = 22/68 (32%), Positives = 29/68 (42%), Gaps = 4/68 (5%)
Query: 1 RCGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGT 60
+C P P N S E G + C EGY+L G + C G+W P+C
Sbjct: 1791 KCKAPGNPENGHSS---GEIYTVGAEVTFSCQEGYQLMGVTKITCLESGEWNHLIPYCKA 1847
Query: 61 NVAFRKPA 68
V+ KPA
Sbjct: 1848 -VSCGKPA 1854
Score = 37.5 bits (83), Expect = 0.26
Identities = 19/78 (24%), Positives = 34/78 (43%)
Query: 889 CISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRK 948
C+ + + + C + C + ENG + + + F ++ C + VG +
Sbjct: 360 CVCREGYRASGQTCELVHCPALKPPENGYFIQNTCNNHFNAACGVRCHPGFDLVGSSIIL 419
Query: 949 CLDDGRWSGEEPSCELAT 966
CL +G WSG E C + T
Sbjct: 420 CLPNGLWSGLESYCRVRT 437
Score = 37.5 bits (83), Expect = 0.26
Identities = 23/77 (29%), Positives = 29/77 (37%), Gaps = 7/77 (9%)
Query: 8 PPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTNVAFRKP 67
P + PN + + G Y+C GY+L G R C G W+ P C P
Sbjct: 2955 PEDLAHGFPNGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSC-------LP 3007
Query: 68 ANQSTTVRGGAAANGND 84
ST V NG D
Sbjct: 3008 CRCSTPVIEYGTVNGTD 3024
Score = 37.1 bits (82), Expect = 0.34
Identities = 16/58 (27%), Positives = 26/58 (44%), Gaps = 3/58 (5%)
Query: 1 RCGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
RCG P P+ + N G + Y C++G+ + G ++ C G W+ P C
Sbjct: 2148 RCGEP---PSIMNGYASGSNYSFGAMVAYSCNKGFYIKGEKKSTCEATGQWSSPIPTC 2202
Score = 37.1 bits (82), Expect = 0.34
Identities = 21/57 (36%), Positives = 26/57 (45%), Gaps = 3/57 (5%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C P V N +V +E I Y C+EG+ L GAR R C G W+ P C
Sbjct: 2836 CSSPPVSANGQVR--GDEYTFQKEIE-YTCNEGFLLEGARSRVCLANGSWSGATPDC 2889
Score = 35.9 bits (79), Expect = 0.79
Identities = 17/48 (35%), Positives = 22/48 (45%)
Query: 29 YECDEGYELFGARQRECTLRGDWTLEPPFCGTNVAFRKPANQSTTVRG 76
YECD GY L G +R C +W + P C P + + VRG
Sbjct: 2802 YECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDCSSPPVSANGQVRG 2849
Score = 34.7 bits (76), Expect = 1.8
Identities = 15/42 (35%), Positives = 19/42 (45%)
Query: 17 NEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
+ N + GT+ Y C+ GYEL G C G W P C
Sbjct: 2674 HSSNFLYGTMVSYTCNPGYELLGNPVLICQEDGTWNGSAPSC 2715
Score = 34.7 bits (76), Expect = 1.8
Identities = 21/57 (36%), Positives = 24/57 (42%), Gaps = 4/57 (7%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
CG PA NA I + G + Y C GY L G + C G WT PP C
Sbjct: 3419 CGPPAHVENA---IARGVHYQYGDMITYSCYSGYMLEGFLRSVCLENGTWT-SPPIC 3471
Score = 34.3 bits (75), Expect = 2.4
Identities = 18/57 (31%), Positives = 23/57 (40%), Gaps = 1/57 (1%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C H P + +S E + T V CDEGY L G+ + C W P C
Sbjct: 438 CPHLRQPKHGHISCSTREMLYKTTCLV-ACDEGYRLEGSDKLTCQGNSQWDGPEPRC 493
Score = 34.3 bits (75), Expect = 2.4
Identities = 18/57 (31%), Positives = 26/57 (45%), Gaps = 3/57 (5%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
CG + PNA +S E + + Y C GY + G+ CT +G W+ P C
Sbjct: 3067 CGSLPMIPNAFIS---ETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVC 3120
Score = 34.3 bits (75), Expect = 2.4
Identities = 18/51 (35%), Positives = 25/51 (49%), Gaps = 3/51 (5%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWT 52
CG P P + V + TI +Y+C+ GYEL G R+R C W+
Sbjct: 3244 CGKPESPEHGFVV--GSKYTFESTI-IYQCEPGYELEGNRERVCQENRQWS 3291
Score = 33.5 bits (73), Expect = 4.2
Identities = 12/35 (34%), Positives = 16/35 (45%)
Query: 24 GTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
G Y C+ G+ L G C GDW ++ P C
Sbjct: 2520 GQTVTYSCNRGFRLEGPSALTCLETGDWDVDAPSC 2554
Score = 33.5 bits (73), Expect = 4.2
Identities = 13/30 (43%), Positives = 16/30 (53%)
Query: 29 YECDEGYELFGARQRECTLRGDWTLEPPFC 58
+ C EGY L GA + C G+W E P C
Sbjct: 2918 FHCHEGYILHGAPKLTCQSDGNWDAEIPLC 2947
Score = 33.1 bits (72), Expect = 5.6
Identities = 17/49 (34%), Positives = 22/49 (44%), Gaps = 2/49 (4%)
Query: 8 PPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPP 56
PP + P + + G IA Y C +GY L Q C +G W PP
Sbjct: 2027 PPIVDHASPETAHRLFGDIAFYYCSDGYSLADNSQLLCNAQGKWV--PP 2073
Score = 33.1 bits (72), Expect = 5.6
Identities = 15/44 (34%), Positives = 19/44 (43%)
Query: 8 PPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDW 51
PP + EN G+ + C+EGYEL G C G W
Sbjct: 2270 PPPIQNGFMKGENFEVGSKVQFFCNEGYELVGDSSWTCQKSGKW 2313
Score = 32.7 bits (71), Expect = 7.4
Identities = 15/51 (29%), Positives = 19/51 (37%)
Query: 8 PPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
PP + ++ N Y C EGY L G EC G W+ C
Sbjct: 1969 PPAIKDAVITGNNFTFRNTVTYTCKEGYTLAGLDTIECLADGKWSRSDQQC 2019
>AL592463-2|CAH73558.1| 3548|Homo sapiens sushi, von Willebrand factor
type A, EGF and pentraxin domain containing 1 protein.
Length = 3548
Score = 313 bits (769), Expect = 2e-84
Identities = 187/624 (29%), Positives = 280/624 (44%), Gaps = 40/624 (6%)
Query: 350 PPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYV 409
P C +P N G Y VG+ + + C EG+ L+G C + G W+ P CK V
Sbjct: 1763 PIKCKAPGNPENGHSSGEIYTVGAEVTFSCQEGYQLMGVTKITCLESGEWNHLIPYCKAV 1822
Query: 410 NCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFD 469
+CG E+G + + T G++ Y C + +TL G+ E +C W P C
Sbjct: 1823 SCGKPAIPENGCIEEL--AFTFGSKVTYRCNKGYTLAGDKESSCLANSSWSHSPPVCEPV 1880
Query: 470 WCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNC 529
C P ++N ++G S ASY+C+ G+ L G + + CT G W PP+C V C
Sbjct: 1881 KCSSPENINNGKYILSGLTYLSTASYSCDTGYSLQGPSIIECTASGIWDRAPPACHLVFC 1940
Query: 530 GTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCP 589
G P K + V+ T+ + +TC+ Y L G + + C DGKWS C SC
Sbjct: 1941 GEPPAIKDA-VITGNNFTFRNTVTYTCKEGYTLAGLDTIECLADGKWSRSDQQCLAVSCD 1999
Query: 590 EPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEW----SGDSPTCEYID 645
EP + E ++C G+ L L+C G+W D P C
Sbjct: 2000 EPPIVDHASPETAHRLFGDIAFYYCSDGYSLADNSQLLCNAQGKWVPPEGQDMPRCIAHF 2059
Query: 646 CGKLPTLPYGTMELLNGTTH-LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDS--SPRCE 702
C K P++ Y +E ++ GSV+ + C + L + C QW+ S S +C
Sbjct: 2060 CEKPPSVSYSILESVSKAKFAAGSVVSFKCMEGFVLNTSAKIECMRGGQWNPSPMSIQCI 2119
Query: 703 EIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGE 762
+RC +P SI+ +G+ G+ Y GA+V Y C KG+ + GE
Sbjct: 2120 PVRCGEP----PSIM--------NGYA---------SGSNYSFGAMVAYSCNKGFYIKGE 2158
Query: 763 SLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGV 822
STCE GQWS PTC V CG P ++ENG + + F YQC+ ++ G
Sbjct: 2159 KKSTCEATGQWSSPIPTCHPVSCGEPPKVENGFLEHTTGRIFESEVR-YQCNPGYKSVGS 2217
Query: 823 IRRMCQENGTWSLEPPI-CKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNL 881
+CQ N W E P+ C + C P I+ G + +G + + C GY L
Sbjct: 2218 PVFVCQANRHWHSESPLMCVPLDCGKP-PPIQNG---FMKGENFEVGSKVQFFCNEGYEL 2273
Query: 882 KGHQTRTCISKGQWN-GTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQ 940
G + TC G+WN + P C+P C P +EN ++V+ +T G V + C +
Sbjct: 2274 VGDSSWTCQKSGKWNKKSNPKCMPAKCPEPPLLEN-QLVLKELTTEVG-VVTFSCKEGHV 2331
Query: 941 RVGPFLRKCLDDGRWSGEEPSCEL 964
GP + KCL +W+ P C++
Sbjct: 2332 LQGPSVLKCLPSQQWNDSFPVCKI 2355
Score = 312 bits (766), Expect = 5e-84
Identities = 187/641 (29%), Positives = 283/641 (44%), Gaps = 41/641 (6%)
Query: 349 LPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSG-APPSCK 407
+P CG P + N + G +++VGS++ + C EG+ L+GD S C+K G W+ + P C
Sbjct: 2237 VPLDCGKPPPIQNGFMKGENFEVGSKVQFFCNEGYELVGDSSWTCQKSGKWNKKSNPKCM 2296
Query: 408 YVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL 467
C P+ + + L + T G +SC+E L G C W+ P C
Sbjct: 2297 PAKCPE-PPLLENQLVLKELTTEVGV-VTFSCKEGHVLQGPSVLKCLPSQQWNDSFPVCK 2354
Query: 468 FDWCPDPPAVS-NASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKY 526
C PP +S + + GS Y+C G L G+++ C G WS P C
Sbjct: 2355 IVLCTPPPLISFGVPIPSSALHFGSTVKYSCVGGFFLRGNSTTLCQPDGTWSSPLPECVP 2414
Query: 527 VNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELT 586
V C P + + G Y S A +TC+P + L G +C +G W P+C+
Sbjct: 2415 VECPQPEEIPNGIIDVQGLA-YLSTALYTCKPGFELVGNTTTLCGENGHWLGGKPTCKAI 2473
Query: 587 SCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDC 646
C +P+ G D + T+ + C G +L G L C + G+W D+P+C I C
Sbjct: 2474 ECLKPKEILNGKFSYTDLHYGQTVTYSCNRGFRLEGPSALTCLETGDWDVDAPSCNAIHC 2533
Query: 647 GKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRC 706
+ G +E G++I YSC +++ G +TC EE WS S P C I C
Sbjct: 2534 DSPQPIENGFVE--GADYSYGAIIIYSCFPGFQVAGHAMQTC-EESGWSSSIPTCMPIDC 2590
Query: 707 SDP-----------------IVAEKSIVSV---TGNDRSHGHTLIRTSDNRDVG-----N 741
P E ++ V T + H + +T +N +
Sbjct: 2591 GLPPHIDFGDCTKLKDDQGYFEQEDDMMEVPYVTPHPPYHLGAVAKTWENTKESPATHSS 2650
Query: 742 TYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSN 801
+ G +V Y C GY+++G + C+++G W+G+ P+C ++C P ENG L
Sbjct: 2651 NFLYGTMVSYTCNPGYELLGNPVLICQEDGTWNGSAPSCISIECDLPTAPENG--FLRFT 2708
Query: 802 ATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVV 861
T G+ Y C L G R+C EN WS P C+ I+C P+ + GS +
Sbjct: 2709 ETSMGSAVQYSCKPGHILAGSDLRLCLENRKWSGASPRCEAISCKKPN-PVMNGS---IK 2764
Query: 862 TSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVIS 921
S + +Y+C+ GY L G + RTC W+ P+CIP+DC SP NG+ +
Sbjct: 2765 GSNYTYLSTLYYECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDCSSPPVSANGQ--VR 2822
Query: 922 NGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
F +EY C + G R CL +G WSG P C
Sbjct: 2823 GDEYTFQKEIEYTCNEGFLLEGARSRVCLANGSWSGATPDC 2863
Score = 297 bits (729), Expect = 1e-79
Identities = 180/617 (29%), Positives = 273/617 (44%), Gaps = 49/617 (7%)
Query: 350 PPTCGSPDKLLNTTILGNDYDV-GSRIVYKCPEGHMLLGDKSRHCKKDGFW-SGAPPSCK 407
P +CG P K+ N + + S + Y+C G+ +G C+ + W S +P C
Sbjct: 2178 PVSCGEPPKVENGFLEHTTGRIFESEVRYQCNPGYKSVGSPVFVCQANRHWHSESPLMCV 2237
Query: 408 YVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEA-PRC 466
++CG PI++G + G++ + C E + LVG+ TC G W+ ++ P+C
Sbjct: 2238 PLDCGKPPPIQNGFMK--GENFEVGSKVQFFCNEGYELVGDSSWTCQKSGKWNKKSNPKC 2295
Query: 467 LFDWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKY 526
+ CP+PP + N V + +++C+ GH+L G + + C W+ P CK
Sbjct: 2296 MPAKCPEPPLLENQLVLKELTTEVGVVTFSCKEGHVLQGPSVLKCLPSQQWNDSFPVCKI 2355
Query: 527 VNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELT 586
V C P + + + +GS +++C ++L G +C DG WS +P C
Sbjct: 2356 VLCTPPPLISFGVPIPSSALHFGSTVKYSCVGGFFLRGNSTTLCQPDGTWSSPLPECVPV 2415
Query: 587 SCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDC 646
CP+PE G ++ ST + C+ G +L+G +C ++G W G PTC+ I+C
Sbjct: 2416 ECPQPEEIPNGIIDVQGLAYLSTALYTCKPGFELVGNTTTLCGENGHWLGGKPTCKAIEC 2475
Query: 647 GKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRC 706
K + G + H G + YSC +RL GP TC E W +P C I C
Sbjct: 2476 LKPKEILNGKFSYTD--LHYGQTVTYSCNRGFRLEGPSALTCLETGDWDVDAPSCNAIHC 2533
Query: 707 SDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLST 766
P E V G Y GA++ Y C G++V G ++ T
Sbjct: 2534 DSPQPIENGFVE---------------------GADYSYGAIIIYSCFPGFQVAGHAMQT 2572
Query: 767 CEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRM 826
CE++G WS + PTC +DCG P I+ G T + Y F Q D+ E+ V
Sbjct: 2573 CEESG-WSSSIPTCMPIDCGLPPHIDFGDCTKLKDDQGY----FEQEDDMMEVPYVTPHP 2627
Query: 827 CQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQT 886
G + KE P+ +S G Y C GY L G+
Sbjct: 2628 PYHLGAVAKTWENTKE----SPATH----------SSNFLYGTMVSYTCNPGYELLGNPV 2673
Query: 887 RTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFL 946
C G WNG+ P CI I+C P ENG + + T GS+V+Y C + G L
Sbjct: 2674 LICQEDGTWNGSAPSCISIECDLPTAPENGFLRFT--ETSMGSAVQYSCKPGHILAGSDL 2731
Query: 947 RKCLDDGRWSGEEPSCE 963
R CL++ +WSG P CE
Sbjct: 2732 RLCLENRKWSGASPRCE 2748
Score = 296 bits (727), Expect = 2e-79
Identities = 186/614 (30%), Positives = 267/614 (43%), Gaps = 36/614 (5%)
Query: 352 TCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNC 411
+C P+ ++N +I G++Y S + Y+C G++L G + R C+ D W P C V+C
Sbjct: 2751 SCKKPNPVMNGSIKGSNYTYLSTLYYECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDC 2810
Query: 412 GGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWC 471
+G V + T Y+C E F L G R C G W G P C+ C
Sbjct: 2811 SSPPVSANGQVR--GDEYTFQKEIEYTCNEGFLLEGARSRVCLANGSWSGATPDCVPVRC 2868
Query: 472 PDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGT 531
PP ++N + ++ C G+IL G+ +TC G W P CK VNCG
Sbjct: 2869 ATPPQLANGVTEGLDYGFMKEVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCKPVNCGP 2928
Query: 532 PTIHKGSFVLING-TTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPE 590
P F NG + +G Q+ C P Y L+G C +G WS PSC C
Sbjct: 2929 PEDLAHGFP--NGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCLPCRCST 2986
Query: 591 PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLP 650
P V G + D+ C G KL+G + C+ DG+WS P CE+ CG LP
Sbjct: 2987 P-VIEYGTVNGTDFDCGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHCEHTSCGSLP 3045
Query: 651 TLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPI 710
+P + ++ +VI YSC + Y + G CTE+ WS P CE + C P
Sbjct: 3046 MIPNAFIS--ETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPLSCGSP- 3102
Query: 711 VAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGES-LSTCED 769
S+ + +H TY + VK RC +GY + ++ TC+
Sbjct: 3103 ---PSVANAVATGEAH---------------TYE--SEVKLRCLEGYTMDTDTDTFTCQK 3142
Query: 770 NGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQE 829
+G+W +C C P I + + + + C E + EGV +CQ
Sbjct: 3143 DGRWFPERISCSPKKCPLPENITH--ILVHGDDFSVNRQVSVSCAEGYTFEGVNISVCQL 3200
Query: 830 NGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTC 889
+GTW EPP E P + ++ VV S + YQCE GY L+G++ R C
Sbjct: 3201 DGTW--EPPFSDESCSPVSCGKPESPEHGFVVGSKYTFESTIIYQCEPGYELEGNRERVC 3258
Query: 890 ISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKC 949
QW+G V +C C +P NGK I N +T G +V Y C Y GP C
Sbjct: 3259 QENRQWSGGVAICKETRCETPLEFLNGKADIENRTT--GPNVVYSCNRGYSLEGPSEAHC 3316
Query: 950 LDDGRWSGEEPSCE 963
++G WS P C+
Sbjct: 3317 TENGTWSHPVPLCK 3330
Score = 292 bits (717), Expect = 4e-78
Identities = 180/620 (29%), Positives = 268/620 (43%), Gaps = 50/620 (8%)
Query: 353 CGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCG 412
C P N + + +GS + Y C GH+L G R C ++ WSGA P C+ ++C
Sbjct: 2694 CDLPTAPENGFLRFTETSMGSAVQYSCKPGHILAGSDLRLCLENRKWSGASPRCEAISCK 2753
Query: 413 GLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCP 472
P+ +G + + T+ + Y C + L G RTC D+ WD + P C+ C
Sbjct: 2754 KPNPVMNGSIK--GSNYTYLSTLYYECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDCS 2811
Query: 473 DPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTP 532
PP +N V + + YTC G +L G+ S C G+WSG P C V C TP
Sbjct: 2812 SPPVSANGQVRGDEYTFQKEIEYTCNEGFLLEGARSRVCLANGSWSGATPDCVPVRCATP 2871
Query: 533 TIHKGSFVLINGTT---TYGSIAQ--FTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTS 587
L NG T YG + + F C Y L+GA +L C DG W +IP C+ +
Sbjct: 2872 P------QLANGVTEGLDYGFMKEVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCKPVN 2925
Query: 588 CPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCG 647
C PE + G+ F + I + C G+KL G + C +G WSG SP+C C
Sbjct: 2926 CGPPEDLAHGFPNGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCLPCRC- 2984
Query: 648 KLPTLPYGTMELLNGTT-HLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRC 706
P + YGT +NGT G + C ++L+G TC + QWS P CE C
Sbjct: 2985 STPVIEYGT---VNGTDFDCGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHCEHTSC 3041
Query: 707 SDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLST 766
+ + +S T + + + ++ Y C GY + G S
Sbjct: 3042 GSLPMIPNAFISETSSWKEN---------------------VITYSCRSGYVIQGSSDLI 3080
Query: 767 CEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELE-GVIRR 825
C + G WS P C+ + CG+P + N T A Y + +C E + ++
Sbjct: 3081 CTEKGVWSQPYPVCEPLSCGSPPSVANAVAT--GEAHTYESEVKLRCLEGYTMDTDTDTF 3138
Query: 826 MCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQ 885
CQ++G W E C CP P + + +LV S+ + C GY +G
Sbjct: 3139 TCQKDGRWFPERISCSPKKCPLP----ENITHILVHGDDFSVNRQVSVSCAEGYTFEGVN 3194
Query: 886 TRTCISKGQWNG--TVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVG 943
C G W + C P+ C P + E+G +V S + F S++ Y C Y+ G
Sbjct: 3195 ISVCQLDGTWEPPFSDESCSPVSCGKPESPEHGFVVGSKYT--FESTIIYQCEPGYELEG 3252
Query: 944 PFLRKCLDDGRWSGEEPSCE 963
R C ++ +WSG C+
Sbjct: 3253 NRERVCQENRQWSGGVAICK 3272
Score = 291 bits (714), Expect = 9e-78
Identities = 176/586 (30%), Positives = 255/586 (43%), Gaps = 38/586 (6%)
Query: 372 GSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRTTH 431
G+ + Y C G+ LLG+ C++DG W+G+ PSC + C T E+G + + T+
Sbjct: 2655 GTMVSYTCNPGYELLGNPVLICQEDGTWNGSAPSCISIECDLPTAPENGFLRFTE--TSM 2712
Query: 432 GARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGS 491
G+ YSC+ L G+ R C + W G +PRC C P V N S+ + + S
Sbjct: 2713 GSAVQYSCKPGHILAGSDLRLCLENRKWSGASPRCEAISCKKPNPVMNGSIKGSNYTYLS 2772
Query: 492 LASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTIHKGSFVLINGTTTYGSI 551
Y C+ G++L+G+ TC W P C V+C +P + V T+
Sbjct: 2773 TLYYECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDCSSPPVSANGQVR-GDEYTFQKE 2831
Query: 552 AQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFDYYVHSTIN 611
++TC + L GA VC +G WS P C C P + G E DY +
Sbjct: 2832 IEYTCNEGFLLEGARSRVCLANGSWSGATPDCVPVRCATPPQLANGVTEGLDYGFMKEVT 2891
Query: 612 FHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHL-GSVI 670
FHC G+ L G P L CQ DG W + P C+ ++CG L +G NG + + G I
Sbjct: 2892 FHCHEGYILHGAPKLTCQSDGNWDAEIPLCKPVNCGPPEDLAHG---FPNGFSFIHGGHI 2948
Query: 671 QYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTL 730
QY C Y+L G R C WS SSP C RCS P++ +V G D
Sbjct: 2949 QYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCLPCRCSTPVI---EYGTVNGTD------- 2998
Query: 731 IRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGR 790
D G RI +C KG+K++G S TCE +GQWS P C++ CG+
Sbjct: 2999 ------FDCGKAARI------QCFKGFKLLGLSEITCEADGQWSSGFPHCEHTSCGSLPM 3046
Query: 791 IENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSA 850
I N ++ +++ Y C + ++G +C E G WS P+C+ ++C P +
Sbjct: 3047 IPNAFIS--ETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPLSCGSPPS 3104
Query: 851 QIKAGSGLLVVTSTLSIGGEAHYQCERGYNL-KGHQTRTCISKGQWNGTVPVCIPIDCRS 909
A + + E +C GY + T TC G+W C P C
Sbjct: 3105 VANA----VATGEAHTYESEVKLRCLEGYTMDTDTDTFTCQKDGRWFPERISCSPKKCPL 3160
Query: 910 PGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRW 955
P NI + I++ V C Y G + C DG W
Sbjct: 3161 PENITH--ILVHGDDFSVNRQVSVSCAEGYTFEGVNISVCQLDGTW 3204
Score = 286 bits (701), Expect = 3e-76
Identities = 183/621 (29%), Positives = 267/621 (42%), Gaps = 43/621 (6%)
Query: 349 LPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKY 408
+P C SP N + G++Y I Y C EG +L G +SR C +G WSGA P C
Sbjct: 2806 IPVDCSSPPVSANGQVRGDEYTFQKEIEYTCNEGFLLEGARSRVCLANGSWSGATPDCVP 2865
Query: 409 VNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLF 468
V C + +G +D + C E + L G P+ TC +G WD E P C
Sbjct: 2866 VRCATPPQLANGVTEGLDYGFMK--EVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCKP 2923
Query: 469 DWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVN 528
C P +++ G Y C G+ L G++S C G+WSG PSC
Sbjct: 2924 VNCGPPEDLAHGFPNGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCLPCR 2983
Query: 529 CGTPTIHKGSFVLINGTT-TYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTS 587
C TP I G+ +NGT G A+ C + L G E+ C DG+WS P CE TS
Sbjct: 2984 CSTPVIEYGT---VNGTDFDCGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHCEHTS 3040
Query: 588 CPE-PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDC 646
C P +P+ ++ + + I + C +G+ + G +L+C + G WS P CE + C
Sbjct: 3041 CGSLPMIPN-AFISETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPLSC 3099
Query: 647 GKLPTLPYGTMELLNGTTH-LGSVIQYSCTTNYRL-VGPVRRTCTEEFQWSDSSPRCEEI 704
G P++ + G H S ++ C Y + TC ++ +W C
Sbjct: 3100 GSPPSV---ANAVATGEAHTYESEVKLRCLEGYTMDTDTDTFTCQKDGRWFPERISCSPK 3156
Query: 705 RCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESL 764
+C P ++T H L+ G+ + + V C +GY G ++
Sbjct: 3157 KCPLP-------ENIT-------HILVH-------GDDFSVNRQVSVSCAEGYTFEGVNI 3195
Query: 765 STCEDNGQWSG--TTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGV 822
S C+ +G W + +C V CG P E+G V + S TF +T YQC+ +ELEG
Sbjct: 3196 SVCQLDGTWEPPFSDESCSPVSCGKPESPEHGFV-VGSKYTF-ESTIIYQCEPGYELEGN 3253
Query: 823 IRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLK 882
R+CQEN WS ICKE C P + + + + G Y C RGY+L+
Sbjct: 3254 RERVCQENRQWSGGVAICKETRCETPLEFLNGKADI----ENRTTGPNVVYSCNRGYSLE 3309
Query: 883 GHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRV 942
G C G W+ VP+C P C P I + +S +V C +
Sbjct: 3310 GPSEAHCTENGTWSHPVPLCKPNPCPVPFVIPENAL-LSEKEFYVDQNVSIKCREGFLLQ 3368
Query: 943 GPFLRKCLDDGRWSGEEPSCE 963
G + C D W+ CE
Sbjct: 3369 GHGIITCNPDETWTQTSAKCE 3389
Score = 274 bits (671), Expect = 1e-72
Identities = 176/621 (28%), Positives = 253/621 (40%), Gaps = 46/621 (7%)
Query: 349 LPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKY 408
+P C +P +L N G DY + + C EG++L G C+ DG W P CK
Sbjct: 2864 VPVRCATPPQLANGVTEGLDYGFMKEVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCKP 2923
Query: 409 VNCGGLTPIEDGDVALIDNRT-THGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL 467
VNCG P ED + + HG Y C + L GN R C G W G +P CL
Sbjct: 2924 VNCG---PPEDLAHGFPNGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCL 2980
Query: 468 FDWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYV 527
C P + +V G A C G L G + +TC G WS P C++
Sbjct: 2981 PCRC-STPVIEYGTVNGTDFDCGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHCEHT 3039
Query: 528 NCGTPTIHKGSFVLINGTTTYG-SIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELT 586
+CG+ + +F I+ T+++ ++ ++C Y + G+ +L+C G WS P CE
Sbjct: 3040 SCGSLPMIPNAF--ISETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPL 3097
Query: 587 SCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPN-LVCQQDGEWSGDSPTCEYID 645
SC P + + S + C G+ + + + CQ+DG W + +C
Sbjct: 3098 SCGSPPSVANAVATGEAHTYESEVKLRCLEGYTMDTDTDTFTCQKDGRWFPERISCSPKK 3157
Query: 646 CGKLPTLPYGTMELLNGTTH-LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSD--SSPRCE 702
C P T L++G + + SC Y G C + W S C
Sbjct: 3158 C---PLPENITHILVHGDDFSVNRQVSVSCAEGYTFEGVNISVCQLDGTWEPPFSDESCS 3214
Query: 703 EIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGE 762
+ C P E HG VG+ Y + + Y+CE GY++ G
Sbjct: 3215 PVSCGKPESPE------------HGFV---------VGSKYTFESTIIYQCEPGYELEGN 3253
Query: 763 SLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGV 822
C++N QWSG C+ C P NGK + + T G Y C+ + LEG
Sbjct: 3254 RERVCQENRQWSGGVAICKETRCETPLEFLNGKADIENRTT--GPNVVYSCNRGYSLEGP 3311
Query: 823 IRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLK 882
C ENGTWS P+CK CP P L+ + +C G+ L+
Sbjct: 3312 SEAHCTENGTWSHPVPLCKPNPCPVP---FVIPENALLSEKEFYVDQNVSIKCREGFLLQ 3368
Query: 883 GHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRV 942
GH TC W T C I C P ++EN + +G + Y C S Y
Sbjct: 3369 GHGIITCNPDETWTQTSAKCEKISCGPPAHVENA--IARGVHYQYGDMITYSCYSGYMLE 3426
Query: 943 GPFLRK-CLDDGRWSGEEPSC 962
G FLR CL++G W+ P C
Sbjct: 3427 G-FLRSVCLENGTWT-SPPIC 3445
Score = 266 bits (653), Expect = 2e-70
Identities = 169/600 (28%), Positives = 259/600 (43%), Gaps = 40/600 (6%)
Query: 372 GSRIVYKCPEGHMLLGDKSRHCKKDGFW---SGAP-PSCKYVNCGGLTPIEDGDVALIDN 427
G Y C +G+ L + C G W G P C C + + +
Sbjct: 2017 GDIAFYYCSDGYSLADNSQLLCNAQGKWVPPEGQDMPRCIAHFCEKPPSVSYSILESVSK 2076
Query: 428 -RTTHGARALYSCRENFTLVGNPERTCGDEGIWDGE--APRCLFDWCPDPPAVSNASVTV 484
+ G+ + C E F L + + C G W+ + +C+ C +PP++ N +
Sbjct: 2077 AKFAAGSVVSFKCMEGFVLNTSAKIECMRGGQWNPSPMSIQCIPVRCGEPPSIMNGYASG 2136
Query: 485 NGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTIHKGSFVLING 544
+ + G++ +Y+C G + G TC G WS P+C V+CG P + F+
Sbjct: 2137 SNYSFGAMVAYSCNKGFYIKGEKKSTCEATGQWSSPIPTCHPVSCGEPPKVENGFLEHTT 2196
Query: 545 TTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIP-SCELTSCPEPEVPSGGYMEAFD 603
+ S ++ C P Y G+ VC + W + P C C +P G+M+ +
Sbjct: 2197 GRIFESEVRYQCNPGYKSVGSPVFVCQANRHWHSESPLMCVPLDCGKPPPIQNGFMKGEN 2256
Query: 604 YYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDS-PTCEYIDCGKLPTLPYGTMELLNG 662
+ V S + F C G++L+G+ + CQ+ G+W+ S P C C + P L + L
Sbjct: 2257 FEVGSKVQFFCNEGYELVGDSSWTCQKSGKWNKKSNPKCMPAKCPEPPLLE-NQLVLKEL 2315
Query: 663 TTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGN 722
TT +G V+ +SC + L GP C QW+DS P C+ + C+ P +
Sbjct: 2316 TTEVG-VVTFSCKEGHVLQGPSVLKCLPSQQWNDSFPVCKIVLCTPPPLI---------- 2364
Query: 723 DRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQY 782
S G + + G+ VKY C G+ + G S + C+ +G WS P C
Sbjct: 2365 --SFGVPI--------PSSALHFGSTVKYSCVGGFFLRGNSTTLCQPDGTWSSPLPECVP 2414
Query: 783 VDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKE 842
V+C P I NG + + A Y +TA Y C +EL G +C ENG W P CK
Sbjct: 2415 VECPQPEEIPNGIIDVQGLA--YLSTALYTCKPGFELVGNTTTLCGENGHWLGGKPTCKA 2472
Query: 843 ITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVC 902
I C P + +G T L G Y C RG+ L+G TC+ G W+ P C
Sbjct: 2473 IECLKPKEIL---NGKFSYTD-LHYGQTVTYSCNRGFRLEGPSALTCLETGDWDVDAPSC 2528
Query: 903 IPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
I C SP IENG + +G+ + Y C +Q G ++ C + G WS P+C
Sbjct: 2529 NAIHCDSPQPIENG--FVEGADYSYGAIIIYSCFPGFQVAGHAMQTCEESG-WSSSIPTC 2585
Score = 266 bits (651), Expect = 4e-70
Identities = 165/537 (30%), Positives = 232/537 (43%), Gaps = 42/537 (7%)
Query: 431 HGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAG 490
+G Y+C + L+GNP C ++G W+G AP C+ C P A N + G
Sbjct: 2654 YGTMVSYTCNPGYELLGNPVLICQEDGTWNGSAPSCISIECDLPTAPENGFLRFTETSMG 2713
Query: 491 SLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPT-IHKGSFVLINGTT-TY 548
S Y+C+ GHIL+GS C WSG P C+ ++C P + GS I G+ TY
Sbjct: 2714 SAVQYSCKPGHILAGSDLRLCLENRKWSGASPRCEAISCKKPNPVMNGS---IKGSNYTY 2770
Query: 549 GSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFDYYVHS 608
S + C+P Y LNG E C D W D P C C P V + G + +Y
Sbjct: 2771 LSTLYYECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDCSSPPVSANGQVRGDEYTFQK 2830
Query: 609 TINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGS 668
I + C G L G + VC +G WSG +P C + C P L G E L+
Sbjct: 2831 EIEYTCNEGFLLEGARSRVCLANGSWSGATPDCVPVRCATPPQLANGVTEGLD--YGFMK 2888
Query: 669 VIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGH 728
+ + C Y L G + TC + W P C+ + C P D +HG
Sbjct: 2889 EVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCKPVNCGPP------------EDLAHGF 2936
Query: 729 TLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNP 788
G ++ G ++Y+C GYK+ G S C NG WSG++P+C C P
Sbjct: 2937 ---------PNGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCLPCRCSTP 2987
Query: 789 GRIENGKVTLPSNATFY--GATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCP 846
IE G V N T + G A QC + ++L G+ C+ +G WS P C+ +C
Sbjct: 2988 -VIEYGTV----NGTDFDCGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHCEHTSC- 3041
Query: 847 DPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPID 906
+ + + TS+ Y C GY ++G C KG W+ PVC P+
Sbjct: 3042 --GSLPMIPNAFISETSSWK-ENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPLS 3098
Query: 907 CRSPGNIENGKIVISNGSTLFGSSVEYYCLSQY-QRVGPFLRKCLDDGRWSGEEPSC 962
C SP ++ N V + + + S V+ CL Y C DGRW E SC
Sbjct: 3099 CGSPPSVANA--VATGEAHTYESEVKLRCLEGYTMDTDTDTFTCQKDGRWFPERISC 3153
Score = 248 bits (607), Expect = 8e-65
Identities = 145/505 (28%), Positives = 219/505 (43%), Gaps = 31/505 (6%)
Query: 347 QYLPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSC 406
Q +P CG P ++N G++Y G+ + Y C +G + G+K C+ G WS P+C
Sbjct: 2117 QCIPVRCGEPPSIMNGYASGSNYSFGAMVAYSCNKGFYIKGEKKSTCEATGQWSSPIPTC 2176
Query: 407 KYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAP-R 465
V+CG +E+G + R + Y C + VG+P C W E+P
Sbjct: 2177 HPVSCGEPPKVENGFLEHTTGRIFE-SEVRYQCNPGYKSVGSPVFVCQANRHWHSESPLM 2235
Query: 466 CLFDWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVP-PSC 524
C+ C PP + N + + GS + C G+ L G +S TC G W+ P C
Sbjct: 2236 CVPLDCGKPPPIQNGFMKGENFEVGSKVQFFCNEGYELVGDSSWTCQKSGKWNKKSNPKC 2295
Query: 525 KYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCE 584
C P + + VL TT G + F+C+ + L G L C +W+ P C+
Sbjct: 2296 MPAKCPEPPLLENQLVLKELTTEVG-VVTFSCKEGHVLQGPSVLKCLPSQQWNDSFPVCK 2354
Query: 585 LTSC-PEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEY 643
+ C P P + G + + + ST+ + C G L G +CQ DG WS P C
Sbjct: 2355 IVLCTPPPLISFGVPIPSSALHFGSTVKYSCVGGFFLRGNSTTLCQPDGTWSSPLPECVP 2414
Query: 644 IDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEE 703
++C + +P G ++ + G +L + + Y+C + LVG C E W P C+
Sbjct: 2415 VECPQPEEIPNGIID-VQGLAYLSTAL-YTCKPGFELVGNTTTLCGENGHWLGGKPTCKA 2472
Query: 704 IRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGES 763
I C P S T D +G T V Y C +G+++ G S
Sbjct: 2473 IECLKPKEILNGKFSYT--DLHYGQT-------------------VTYSCNRGFRLEGPS 2511
Query: 764 LSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVI 823
TC + G W P+C + C +P IENG V + YGA Y C +++ G
Sbjct: 2512 ALTCLETGDWDVDAPSCNAIHCDSPQPIENGFVEGADYS--YGAIIIYSCFPGFQVAGHA 2569
Query: 824 RRMCQENGTWSLEPPICKEITCPDP 848
+ C+E+G WS P C I C P
Sbjct: 2570 MQTCEESG-WSSSIPTCMPIDCGLP 2593
Score = 239 bits (586), Expect = 3e-62
Identities = 168/620 (27%), Positives = 258/620 (41%), Gaps = 63/620 (10%)
Query: 352 TCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVN- 410
+CG P L N +D+ GS + Y+C G+ LLGD C +G W+G PSC V+
Sbjct: 1666 SCGVPPPLENGFHSADDFYAGSTVTYQCNNGYYLLGDSRMFCTDNGSWNGVSPSCLDVDE 1725
Query: 411 CG-GLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFD 469
C G E +D + SC +T G + C E +C
Sbjct: 1726 CAVGSDCSEHASCLNVD------GSYICSCVPPYTGDG---KNC-------AEPIKCK-- 1767
Query: 470 WCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNC 529
P P ++S + + G+ +++C+ G+ L G T +TC G W+ + P CK V+C
Sbjct: 1768 -APGNPENGHSSGEI--YTVGAEVTFSCQEGYQLMGVTKITCLESGEWNHLIPYCKAVSC 1824
Query: 530 GTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCP 589
G P I + + T+GS + C Y L G +E C + WS+ P CE C
Sbjct: 1825 GKPAIPENG-CIEELAFTFGSKVTYRCNKGYTLAGDKESSCLANSSWSHSPPVCEPVKCS 1883
Query: 590 EPE-VPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGK 648
PE + +G Y+ + Y+ ST ++ C+ G+ L G + C G W P C + CG+
Sbjct: 1884 SPENINNGKYILSGLTYL-STASYSCDTGYSLQGPSIIECTASGIWDRAPPACHLVFCGE 1942
Query: 649 LPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSD 708
P + + N T + + Y+C Y L G C + +WS S +C + C +
Sbjct: 1943 PPAIKDAVITGNNFT--FRNTVTYTCKEGYTLAGLDTIECLADGKWSRSDQQCLAVSCDE 2000
Query: 709 PIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCE 768
P + + + H L G + Y C GY + S C
Sbjct: 2001 PPIVDHA-------SPETAHRL--------------FGDIAFYYCSDGYSLADNSQLLCN 2039
Query: 769 DNGQW----SGTTPTCQYVDCGNPGRIENGKVTLPSNATF-YGATAFYQCDENWELEGVI 823
G+W P C C P + + S A F G+ ++C E + L
Sbjct: 2040 AQGKWVPPEGQDMPRCIAHFCEKPPSVSYSILESVSKAKFAAGSVVSFKCMEGFVLNTSA 2099
Query: 824 RRMCQENGTWSLEPPI--CKEITCPDPSAQIKA-GSGLLVVTSTLSIGGEAHYQCERGYN 880
+ C G W+ P C + C +P + + SG S S G Y C +G+
Sbjct: 2100 KIECMRGGQWNPSPMSIQCIPVRCGEPPSIMNGYASG-----SNYSFGAMVAYSCNKGFY 2154
Query: 881 LKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQ 940
+KG + TC + GQW+ +P C P+ C P +ENG + + G +F S V Y C Y+
Sbjct: 2155 IKGEKKSTCEATGQWSSPIPTCHPVSCGEPPKVENGFLEHTTG-RIFESEVRYQCNPGYK 2213
Query: 941 RVGPFLRKCLDDGRWSGEEP 960
VG + C + W E P
Sbjct: 2214 SVGSPVFVCQANRHWHSESP 2233
Score = 234 bits (572), Expect = 1e-60
Identities = 159/605 (26%), Positives = 252/605 (41%), Gaps = 62/605 (10%)
Query: 368 DYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDN 427
D GS++ C G L+G+ ++C G W+ P C+ ++CG P+E+G + D
Sbjct: 1624 DLKPGSKVNLFCDPGFQLVGNPVQYCLNQGQWTQPLPHCERISCGVPPPLENGFHSADDF 1683
Query: 428 RTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL-FDWCPDPPAVSNASVTVNG 486
G+ Y C + L+G+ C D G W+G +P CL D C
Sbjct: 1684 YA--GSTVTYQCNNGYYLLGDSRMFCTDNGSWNGVSPSCLDVDEC--------------- 1726
Query: 487 HKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSC-KYVNCGTPTIHKGSFVLINGT 545
++ S E+ L+ S C+ ++G +C + + C P +
Sbjct: 1727 ----AVGSDCSEHASCLNVDGSYICSCVPPYTGDGKNCAEPIKCKAPGNPENGH-SSGEI 1781
Query: 546 TTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFDYY 605
T G+ F+C+ Y L G ++ C G+W++ IP C+ SC +P +P G +E +
Sbjct: 1782 YTVGAEVTFSCQEGYQLMGVTKITCLESGEWNHLIPYCKAVSCGKPAIPENGCIEELAFT 1841
Query: 606 VHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTH 665
S + + C G+ L G+ C + WS P CE + C + G +L+G T+
Sbjct: 1842 FGSKVTYRCNKGYTLAGDKESSCLANSSWSHSPPVCEPVKCSSPENINNGKY-ILSGLTY 1900
Query: 666 LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRS 725
L S YSC T Y L GP CT W + P C + C +P + ++++
Sbjct: 1901 L-STASYSCDTGYSLQGPSIIECTASGIWDRAPPACHLVFCGEPPAIKDAVIT------- 1952
Query: 726 HGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDC 785
GN + V Y C++GY + G C +G+WS + C V C
Sbjct: 1953 --------------GNNFTFRNTVTYTCKEGYTLAGLDTIECLADGKWSRSDQQCLAVSC 1998
Query: 786 GNPGRIENGKVTLPSNA-TFYGATAFYQCDENWELEGVIRRMCQENGTW----SLEPPIC 840
P +++ P A +G AFY C + + L + +C G W + P C
Sbjct: 1999 DEPPIVDHAS---PETAHRLFGDIAFYYCSDGYSLADNSQLLCNAQGKWVPPEGQDMPRC 2055
Query: 841 KEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVP 900
C P + + V + + G ++C G+ L C+ GQWN + P
Sbjct: 2056 IAHFCEKPPS-VSYSILESVSKAKFAAGSVVSFKCMEGFVLNTSAKIECMRGGQWNPS-P 2113
Query: 901 V---CIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSG 957
+ CIP+ C P +I NG SN S FG+ V Y C + G C G+WS
Sbjct: 2114 MSIQCIPVRCGEPPSIMNGYASGSNYS--FGAMVAYSCNKGFYIKGEKKSTCEATGQWSS 2171
Query: 958 EEPSC 962
P+C
Sbjct: 2172 PIPTC 2176
Score = 165 bits (402), Expect = 6e-40
Identities = 124/483 (25%), Positives = 191/483 (39%), Gaps = 49/483 (10%)
Query: 352 TCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNC 411
+CGS + N I + I Y C G+++ G C + G WS P C+ ++C
Sbjct: 3040 SCGSLPMIPNAFISETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPLSC 3099
Query: 412 GGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPER-TCGDEGIWDGEAPRCLFDW 470
G +P + T+ + C E +T+ + + TC +G W E C
Sbjct: 3100 G--SPPSVANAVATGEAHTYESEVKLRCLEGYTMDTDTDTFTCQKDGRWFPERISCSPKK 3157
Query: 471 CPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPP----SCKY 526
CP P +++ V + S +C G+ G C L G W PP SC
Sbjct: 3158 CPLPENITHILVHGDDFSVNRQVSVSCAEGYTFEGVNISVCQLDGTWE--PPFSDESCSP 3215
Query: 527 VNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELT 586
V+CG P + FV + T+ S + CEP Y L G E VC + +WS + C+ T
Sbjct: 3216 VSCGKPESPEHGFV-VGSKYTFESTIIYQCEPGYELEGNRERVCQENRQWSGGVAICKET 3274
Query: 587 SCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDC 646
C P G + + + + C G+ L G C ++G WS P C+ C
Sbjct: 3275 RCETPLEFLNGKADIENRTTGPNVVYSCNRGYSLEGPSEAHCTENGTWSHPVPLCKPNPC 3334
Query: 647 GKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRC 706
+P + L ++ + C + L G TC + W+ +S +CE+I C
Sbjct: 3335 PVPFVIPENAL-LSEKEFYVDQNVSIKCREGFLLQGHGIITCNPDETWTQTSAKCEKISC 3393
Query: 707 SDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLST 766
P E +I G Y+ G ++ Y C GY + G S
Sbjct: 3394 GPPAHVENAIAR---------------------GVHYQYGDMITYSCYSGYMLEGFLRSV 3432
Query: 767 CEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRM 826
C +NG W+ + P C+ V C P +NG + NA C E W + R+
Sbjct: 3433 CLENGTWT-SPPICRAV-CRFP--CQNGGICQRPNAC--------SCPEGW-----MGRL 3475
Query: 827 CQE 829
C+E
Sbjct: 3476 CEE 3478
Score = 153 bits (371), Expect = 3e-36
Identities = 103/369 (27%), Positives = 145/369 (39%), Gaps = 13/369 (3%)
Query: 345 ICQYLPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRH-CKKDGFWSGAP 403
+C+ P +CGSP + N G + S + +C EG+ + D C+KDG W
Sbjct: 3093 VCE--PLSCGSPPSVANAVATGEAHTYESEVKLRCLEGYTMDTDTDTFTCQKDGRWFPER 3150
Query: 404 PSCKYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDG-- 461
SC C P + + + + + SC E +T G C +G W+
Sbjct: 3151 ISCSPKKCP--LPENITHILVHGDDFSVNRQVSVSCAEGYTFEGVNISVCQLDGTWEPPF 3208
Query: 462 EAPRCLFDWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVP 521
C C P + + V + + S Y CE G+ L G+ C WSG
Sbjct: 3209 SDESCSPVSCGKPESPEHGFVVGSKYTFESTIIYQCEPGYELEGNRERVCQENRQWSGGV 3268
Query: 522 PSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIP 581
CK C TP I TT G ++C Y L G E C +G WS+ +P
Sbjct: 3269 AICKETRCETPLEFLNGKADIENRTT-GPNVVYSCNRGYSLEGPSEAHCTENGTWSHPVP 3327
Query: 582 SCELTSCPEPEV-PSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPT 640
C+ CP P V P + ++YV ++ C G L G + C D W+ S
Sbjct: 3328 LCKPNPCPVPFVIPENALLSEKEFYVDQNVSIKCREGFLLQGHGIITCNPDETWTQTSAK 3387
Query: 641 CEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPR 700
CE I CG P G +I YSC + Y L G +R C E W+ S P
Sbjct: 3388 CEKISCG--PPAHVENAIARGVHYQYGDMITYSCYSGYMLEGFLRSVCLENGTWT-SPPI 3444
Query: 701 CEEIRCSDP 709
C + C P
Sbjct: 3445 CRAV-CRFP 3452
Score = 128 bits (309), Expect = 1e-28
Identities = 100/347 (28%), Positives = 146/347 (42%), Gaps = 38/347 (10%)
Query: 644 IDCGKLPTLPYGTMELLNGTTHL--GSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRC 701
I C P L L + L GS + C ++LVG + C + QW+ P C
Sbjct: 1603 IFCSDCPRLGGSVPHLRTASEDLKPGSKVNLFCDPGFQLVGNPVQYCLNQGQWTQPLPHC 1662
Query: 702 EEIRCSDPIVAEKSIVSV----TGNDRSH----GHTLIRTSDN--RDVG--NTYRIGALV 749
E I C P E S G+ ++ G+ L+ S D G N L
Sbjct: 1663 ERISCGVPPPLENGFHSADDFYAGSTVTYQCNNGYYLLGDSRMFCTDNGSWNGVSPSCLD 1722
Query: 750 KYRCEKG---------YKVIGESLSTCEDNGQWSGTTPTC-QYVDCGNPGRIENGKVTLP 799
C G V G + +C ++G C + + C PG ENG
Sbjct: 1723 VDECAVGSDCSEHASCLNVDGSYICSCVP--PYTGDGKNCAEPIKCKAPGNPENGH---- 1776
Query: 800 SNATFY--GATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSG 857
S+ Y GA + C E ++L GV + C E+G W+ P CK ++C P+
Sbjct: 1777 SSGEIYTVGAEVTFSCQEGYQLMGVTKITCLESGEWNHLIPYCKAVSCGKPAIPENGCIE 1836
Query: 858 LLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGK 917
L T G + Y+C +GY L G + +C++ W+ + PVC P+ C SP NI NGK
Sbjct: 1837 ELAFT----FGSKVTYRCNKGYTLAGDKESSCLANSSWSHSPPVCEPVKCSSPENINNGK 1892
Query: 918 IVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCEL 964
++S G T + S+ Y C + Y GP + +C G W P+C L
Sbjct: 1893 YILS-GLT-YLSTASYSCDTGYSLQGPSIIECTASGIWDRAPPACHL 1937
Score = 77.4 bits (182), Expect = 3e-13
Identities = 44/163 (26%), Positives = 68/163 (41%), Gaps = 6/163 (3%)
Query: 752 RCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFY 811
RC G+ ++G S+ C NG WSG+ C+ C + + ++G ++ + Y T
Sbjct: 382 RCHPGFDLVGSSIILCLPNGLWSGSESYCRVRTCPHLRQPKHGHISCSTREMLYKTTCLV 441
Query: 812 QCDENWELEGVIRRMCQENGTWSLEPPICKEITCPD---PSAQIKAGSGLLVVTSTLSIG 868
CDE + LEG + CQ N W P C E C P I + G
Sbjct: 442 ACDEGYRLEGSDKLTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISPHN--CGKQPAKFG 499
Query: 869 GEAHYQCERGYNLKG-HQTRTCISKGQWNGTVPVCIPIDCRSP 910
+ C +G+ L G + C + G+WN V + D +P
Sbjct: 500 TICYVSCRQGFILSGVKEMLRCTTSGKWNVGVQAAVCKDVEAP 542
Score = 76.6 bits (180), Expect = 5e-13
Identities = 47/196 (23%), Positives = 76/196 (38%), Gaps = 7/196 (3%)
Query: 405 SCKYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAP 464
+C+ V+C L P E+G A C F LVG+ C G+W G
Sbjct: 349 TCELVHCPALKPPENGYFIQNTCNNHFNAACGVRCHPGFDLVGSSIILCLPNGLWSGSES 408
Query: 465 RCLFDWCPD--PPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPP 522
C CP P + S + + C+ G+ L GS +TC W G P
Sbjct: 409 YCRVRTCPHLRQPKHGHISCSTREMLYKTTCLVACDEGYRLEGSDKLTCQGNSQWDGPEP 468
Query: 523 SCKYVNCGTPTIHKGSFVLING----TTTYGSIAQFTCEPDYWLNGAEELV-CNRDGKWS 577
C +C T + K + + +G+I +C + L+G +E++ C GKW+
Sbjct: 469 RCVERHCSTFQMPKDVIISPHNCGKQPAKFGTICYVSCRQGFILSGVKEMLRCTTSGKWN 528
Query: 578 YDIPSCELTSCPEPEV 593
+ + P++
Sbjct: 529 VGVQAAVCKDVEAPQI 544
Score = 74.1 bits (174), Expect = 2e-12
Identities = 46/158 (29%), Positives = 68/158 (43%), Gaps = 8/158 (5%)
Query: 378 KCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRTTHGARALY 437
+C G L+G C +G WSG+ C+ C L + G ++ + L
Sbjct: 382 RCHPGFDLVGSSIILCLPNGLWSGSESYCRVRTCPHLRQPKHGHISCSTREMLYKTTCLV 441
Query: 438 SCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWC-----PDPPAVSNASVTVNGHKAGSL 492
+C E + L G+ + TC WDG PRC+ C P +S + K G++
Sbjct: 442 ACDEGYRLEGSDKLTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISPHNCGKQPAKFGTI 501
Query: 493 ASYTCENGHILSG-STSVTCTLGGAWS-GVPPS-CKYV 527
+C G ILSG + CT G W+ GV + CK V
Sbjct: 502 CYVSCRQGFILSGVKEMLRCTTSGKWNVGVQAAVCKDV 539
Score = 72.5 bits (170), Expect = 7e-12
Identities = 43/155 (27%), Positives = 64/155 (41%), Gaps = 4/155 (2%)
Query: 566 EELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYM--EAFDYYVHSTINFHCEAGHKLIGE 623
E+ VC R+G + +CEL CP + P GY + + ++ C G L+G
Sbjct: 335 EDCVC-REG-YRASGQTCELVHCPALKPPENGYFIQNTCNNHFNAACGVRCHPGFDLVGS 392
Query: 624 PNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGP 683
++C +G WSG C C L +G + + +C YRL G
Sbjct: 393 SIILCLPNGLWSGSESYCRVRTCPHLRQPKHGHISCSTREMLYKTTCLVACDEGYRLEGS 452
Query: 684 VRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVS 718
+ TC QW PRC E CS + + I+S
Sbjct: 453 DKLTCQGNSQWDGPEPRCVERHCSTFQMPKDVIIS 487
Score = 72.1 bits (169), Expect = 1e-11
Identities = 39/122 (31%), Positives = 57/122 (46%), Gaps = 2/122 (1%)
Query: 841 KEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVP 900
K I C D + L + L G + + C+ G+ L G+ + C+++GQW +P
Sbjct: 1601 KSIFCSDCPRLGGSVPHLRTASEDLKPGSKVNLFCDPGFQLVGNPVQYCLNQGQWTQPLP 1660
Query: 901 VCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEP 960
C I C P +ENG S GS+V Y C + Y +G C D+G W+G P
Sbjct: 1661 HCERISCGVPPPLENG--FHSADDFYAGSTVTYQCNNGYYLLGDSRMFCTDNGSWNGVSP 1718
Query: 961 SC 962
SC
Sbjct: 1719 SC 1720
Score = 63.7 bits (148), Expect = 3e-09
Identities = 47/206 (22%), Positives = 78/206 (37%), Gaps = 8/206 (3%)
Query: 498 ENGHILSGSTSVT-CTLGGAWSGVPPSCKYVNC-GTPTIHKGSFVLINGTTTYGSIAQFT 555
EN GSTS C + +C+ V+C G F+ + +
Sbjct: 323 ENHTSPPGSTSPEDCVCREGYRASGQTCELVHCPALKPPENGYFIQNTCNNHFNAACGVR 382
Query: 556 CEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAF--DYYVHSTINFH 613
C P + L G+ ++C +G WS C + +CP P G++ + +T
Sbjct: 383 CHPGFDLVGSSIILCLPNGLWSGSESYCRVRTCPHLRQPKHGHISCSTREMLYKTTCLVA 442
Query: 614 CEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCG--KLP-TLPYGTMELLNGTTHLGSVI 670
C+ G++L G L CQ + +W G P C C ++P + G++
Sbjct: 443 CDEGYRLEGSDKLTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISPHNCGKQPAKFGTIC 502
Query: 671 QYSCTTNYRLVGPVRR-TCTEEFQWS 695
SC + L G CT +W+
Sbjct: 503 YVSCRQGFILSGVKEMLRCTTSGKWN 528
Score = 60.9 bits (141), Expect = 2e-08
Identities = 48/194 (24%), Positives = 73/194 (37%), Gaps = 8/194 (4%)
Query: 767 CEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRM 826
C + + SG T C+ V C ENG + + A +C ++L G +
Sbjct: 339 CREGYRASGQT--CELVHCPALKPPENGYFIQNTCNNHFNAACGVRCHPGFDLVGSSIIL 396
Query: 827 CQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQT 886
C NG WS C+ TCP Q K G + T + C+ GY L+G
Sbjct: 397 CLPNGLWSGSESYCRVRTCPH-LRQPKHGH-ISCSTREMLYKTTCLVACDEGYRLEGSDK 454
Query: 887 RTCISKGQWNGTVPVCIPIDC---RSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVG 943
TC QW+G P C+ C + P ++ FG+ C + G
Sbjct: 455 LTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISPHNCGKQPAKFGTICYVSCRQGFILSG 514
Query: 944 -PFLRKCLDDGRWS 956
+ +C G+W+
Sbjct: 515 VKEMLRCTTSGKWN 528
Score = 46.0 bits (104), Expect = 7e-04
Identities = 23/89 (25%), Positives = 37/89 (41%)
Query: 874 QCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEY 933
+C G++L G C+ G W+G+ C C ++G I S L+ ++
Sbjct: 382 RCHPGFDLVGSSIILCLPNGLWSGSESYCRVRTCPHLRQPKHGHISCSTREMLYKTTCLV 441
Query: 934 YCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
C Y+ G C + +W G EP C
Sbjct: 442 ACDEGYRLEGSDKLTCQGNSQWDGPEPRC 470
Score = 46.0 bits (104), Expect = 7e-04
Identities = 19/57 (33%), Positives = 27/57 (47%), Gaps = 3/57 (5%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
CG PA+P N + E G+ Y C++GY L G ++ C W+ PP C
Sbjct: 1824 CGKPAIPENGCIE---ELAFTFGSKVTYRCNKGYTLAGDKESSCLANSSWSHSPPVC 1877
Score = 42.3 bits (95), Expect = 0.009
Identities = 22/61 (36%), Positives = 26/61 (42%), Gaps = 3/61 (4%)
Query: 1 RCGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGT 60
RC P N + I EN G VY C+ GY L G + CT G W+ P C
Sbjct: 3275 RCETPLEFLNGKADI---ENRTTGPNVVYSCNRGYSLEGPSEAHCTENGTWSHPVPLCKP 3331
Query: 61 N 61
N
Sbjct: 3332 N 3332
Score = 40.3 bits (90), Expect = 0.037
Identities = 17/52 (32%), Positives = 24/52 (46%)
Query: 7 VPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
VPP + ++ AG+ Y+C+ GY L G + CT G W P C
Sbjct: 1669 VPPPLENGFHSADDFYAGSTVTYQCNNGYYLLGDSRMFCTDNGSWNGVSPSC 1720
Score = 40.3 bits (90), Expect = 0.037
Identities = 23/67 (34%), Positives = 30/67 (44%), Gaps = 4/67 (5%)
Query: 14 SIPNEENIVAG----TIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTNVAFRKPAN 69
+I N + I++G + A Y CD GY L G ECT G W PP C PA
Sbjct: 1887 NINNGKYILSGLTYLSTASYSCDTGYSLQGPSIIECTASGIWDRAPPACHLVFCGEPPAI 1946
Query: 70 QSTTVRG 76
+ + G
Sbjct: 1947 KDAVITG 1953
Score = 39.1 bits (87), Expect = 0.085
Identities = 22/68 (32%), Positives = 29/68 (42%), Gaps = 4/68 (5%)
Query: 1 RCGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGT 60
+C P P N S E G + C EGY+L G + C G+W P+C
Sbjct: 1765 KCKAPGNPENGHSS---GEIYTVGAEVTFSCQEGYQLMGVTKITCLESGEWNHLIPYCKA 1821
Query: 61 NVAFRKPA 68
V+ KPA
Sbjct: 1822 -VSCGKPA 1828
Score = 38.7 bits (86), Expect = 0.11
Identities = 19/78 (24%), Positives = 34/78 (43%)
Query: 889 CISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRK 948
C+ + + + C + C + ENG + + + F ++ C + VG +
Sbjct: 337 CVCREGYRASGQTCELVHCPALKPPENGYFIQNTCNNHFNAACGVRCHPGFDLVGSSIIL 396
Query: 949 CLDDGRWSGEEPSCELAT 966
CL +G WSG E C + T
Sbjct: 397 CLPNGLWSGSESYCRVRT 414
Score = 37.5 bits (83), Expect = 0.26
Identities = 23/77 (29%), Positives = 29/77 (37%), Gaps = 7/77 (9%)
Query: 8 PPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTNVAFRKP 67
P + PN + + G Y+C GY+L G R C G W+ P C P
Sbjct: 2929 PEDLAHGFPNGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSC-------LP 2981
Query: 68 ANQSTTVRGGAAANGND 84
ST V NG D
Sbjct: 2982 CRCSTPVIEYGTVNGTD 2998
Score = 37.1 bits (82), Expect = 0.34
Identities = 16/58 (27%), Positives = 26/58 (44%), Gaps = 3/58 (5%)
Query: 1 RCGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
RCG P P+ + N G + Y C++G+ + G ++ C G W+ P C
Sbjct: 2122 RCGEP---PSIMNGYASGSNYSFGAMVAYSCNKGFYIKGEKKSTCEATGQWSSPIPTC 2176
Score = 37.1 bits (82), Expect = 0.34
Identities = 21/57 (36%), Positives = 26/57 (45%), Gaps = 3/57 (5%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C P V N +V +E I Y C+EG+ L GAR R C G W+ P C
Sbjct: 2810 CSSPPVSANGQVR--GDEYTFQKEIE-YTCNEGFLLEGARSRVCLANGSWSGATPDC 2863
Score = 35.9 bits (79), Expect = 0.79
Identities = 17/48 (35%), Positives = 22/48 (45%)
Query: 29 YECDEGYELFGARQRECTLRGDWTLEPPFCGTNVAFRKPANQSTTVRG 76
YECD GY L G +R C +W + P C P + + VRG
Sbjct: 2776 YECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDCSSPPVSANGQVRG 2823
Score = 34.7 bits (76), Expect = 1.8
Identities = 15/42 (35%), Positives = 19/42 (45%)
Query: 17 NEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
+ N + GT+ Y C+ GYEL G C G W P C
Sbjct: 2648 HSSNFLYGTMVSYTCNPGYELLGNPVLICQEDGTWNGSAPSC 2689
Score = 34.7 bits (76), Expect = 1.8
Identities = 21/57 (36%), Positives = 24/57 (42%), Gaps = 4/57 (7%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
CG PA NA I + G + Y C GY L G + C G WT PP C
Sbjct: 3393 CGPPAHVENA---IARGVHYQYGDMITYSCYSGYMLEGFLRSVCLENGTWT-SPPIC 3445
Score = 34.3 bits (75), Expect = 2.4
Identities = 18/57 (31%), Positives = 23/57 (40%), Gaps = 1/57 (1%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C H P + +S E + T V CDEGY L G+ + C W P C
Sbjct: 415 CPHLRQPKHGHISCSTREMLYKTTCLV-ACDEGYRLEGSDKLTCQGNSQWDGPEPRC 470
Score = 34.3 bits (75), Expect = 2.4
Identities = 18/57 (31%), Positives = 26/57 (45%), Gaps = 3/57 (5%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
CG + PNA +S E + + Y C GY + G+ CT +G W+ P C
Sbjct: 3041 CGSLPMIPNAFIS---ETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVC 3094
Score = 34.3 bits (75), Expect = 2.4
Identities = 18/51 (35%), Positives = 25/51 (49%), Gaps = 3/51 (5%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWT 52
CG P P + V + TI +Y+C+ GYEL G R+R C W+
Sbjct: 3218 CGKPESPEHGFVV--GSKYTFESTI-IYQCEPGYELEGNRERVCQENRQWS 3265
Score = 33.5 bits (73), Expect = 4.2
Identities = 12/35 (34%), Positives = 16/35 (45%)
Query: 24 GTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
G Y C+ G+ L G C GDW ++ P C
Sbjct: 2494 GQTVTYSCNRGFRLEGPSALTCLETGDWDVDAPSC 2528
Score = 33.5 bits (73), Expect = 4.2
Identities = 13/30 (43%), Positives = 16/30 (53%)
Query: 29 YECDEGYELFGARQRECTLRGDWTLEPPFC 58
+ C EGY L GA + C G+W E P C
Sbjct: 2892 FHCHEGYILHGAPKLTCQSDGNWDAEIPLC 2921
Score = 33.1 bits (72), Expect = 5.6
Identities = 17/49 (34%), Positives = 22/49 (44%), Gaps = 2/49 (4%)
Query: 8 PPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPP 56
PP + P + + G IA Y C +GY L Q C +G W PP
Sbjct: 2001 PPIVDHASPETAHRLFGDIAFYYCSDGYSLADNSQLLCNAQGKWV--PP 2047
Score = 33.1 bits (72), Expect = 5.6
Identities = 15/44 (34%), Positives = 19/44 (43%)
Query: 8 PPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDW 51
PP + EN G+ + C+EGYEL G C G W
Sbjct: 2244 PPPIQNGFMKGENFEVGSKVQFFCNEGYELVGDSSWTCQKSGKW 2287
Score = 32.7 bits (71), Expect = 7.4
Identities = 15/51 (29%), Positives = 19/51 (37%)
Query: 8 PPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
PP + ++ N Y C EGY L G EC G W+ C
Sbjct: 1943 PPAIKDAVITGNNFTFRNTVTYTCKEGYTLAGLDTIECLADGKWSRSDQQC 1993
>AL354982-2|CAH74139.1| 3548|Homo sapiens sushi, von Willebrand factor
type A, EGF and pentraxin domain containing 1 protein.
Length = 3548
Score = 313 bits (769), Expect = 2e-84
Identities = 187/624 (29%), Positives = 280/624 (44%), Gaps = 40/624 (6%)
Query: 350 PPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYV 409
P C +P N G Y VG+ + + C EG+ L+G C + G W+ P CK V
Sbjct: 1763 PIKCKAPGNPENGHSSGEIYTVGAEVTFSCQEGYQLMGVTKITCLESGEWNHLIPYCKAV 1822
Query: 410 NCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFD 469
+CG E+G + + T G++ Y C + +TL G+ E +C W P C
Sbjct: 1823 SCGKPAIPENGCIEEL--AFTFGSKVTYRCNKGYTLAGDKESSCLANSSWSHSPPVCEPV 1880
Query: 470 WCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNC 529
C P ++N ++G S ASY+C+ G+ L G + + CT G W PP+C V C
Sbjct: 1881 KCSSPENINNGKYILSGLTYLSTASYSCDTGYSLQGPSIIECTASGIWDRAPPACHLVFC 1940
Query: 530 GTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCP 589
G P K + V+ T+ + +TC+ Y L G + + C DGKWS C SC
Sbjct: 1941 GEPPAIKDA-VITGNNFTFRNTVTYTCKEGYTLAGLDTIECLADGKWSRSDQQCLAVSCD 1999
Query: 590 EPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEW----SGDSPTCEYID 645
EP + E ++C G+ L L+C G+W D P C
Sbjct: 2000 EPPIVDHASPETAHRLFGDIAFYYCSDGYSLADNSQLLCNAQGKWVPPEGQDMPRCIAHF 2059
Query: 646 CGKLPTLPYGTMELLNGTTH-LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDS--SPRCE 702
C K P++ Y +E ++ GSV+ + C + L + C QW+ S S +C
Sbjct: 2060 CEKPPSVSYSILESVSKAKFAAGSVVSFKCMEGFVLNTSAKIECMRGGQWNPSPMSIQCI 2119
Query: 703 EIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGE 762
+RC +P SI+ +G+ G+ Y GA+V Y C KG+ + GE
Sbjct: 2120 PVRCGEP----PSIM--------NGYA---------SGSNYSFGAMVAYSCNKGFYIKGE 2158
Query: 763 SLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGV 822
STCE GQWS PTC V CG P ++ENG + + F YQC+ ++ G
Sbjct: 2159 KKSTCEATGQWSSPIPTCHPVSCGEPPKVENGFLEHTTGRIFESEVR-YQCNPGYKSVGS 2217
Query: 823 IRRMCQENGTWSLEPPI-CKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNL 881
+CQ N W E P+ C + C P I+ G + +G + + C GY L
Sbjct: 2218 PVFVCQANRHWHSESPLMCVPLDCGKP-PPIQNG---FMKGENFEVGSKVQFFCNEGYEL 2273
Query: 882 KGHQTRTCISKGQWN-GTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQ 940
G + TC G+WN + P C+P C P +EN ++V+ +T G V + C +
Sbjct: 2274 VGDSSWTCQKSGKWNKKSNPKCMPAKCPEPPLLEN-QLVLKELTTEVG-VVTFSCKEGHV 2331
Query: 941 RVGPFLRKCLDDGRWSGEEPSCEL 964
GP + KCL +W+ P C++
Sbjct: 2332 LQGPSVLKCLPSQQWNDSFPVCKI 2355
Score = 312 bits (766), Expect = 5e-84
Identities = 187/641 (29%), Positives = 283/641 (44%), Gaps = 41/641 (6%)
Query: 349 LPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSG-APPSCK 407
+P CG P + N + G +++VGS++ + C EG+ L+GD S C+K G W+ + P C
Sbjct: 2237 VPLDCGKPPPIQNGFMKGENFEVGSKVQFFCNEGYELVGDSSWTCQKSGKWNKKSNPKCM 2296
Query: 408 YVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL 467
C P+ + + L + T G +SC+E L G C W+ P C
Sbjct: 2297 PAKCPE-PPLLENQLVLKELTTEVGV-VTFSCKEGHVLQGPSVLKCLPSQQWNDSFPVCK 2354
Query: 468 FDWCPDPPAVS-NASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKY 526
C PP +S + + GS Y+C G L G+++ C G WS P C
Sbjct: 2355 IVLCTPPPLISFGVPIPSSALHFGSTVKYSCVGGFFLRGNSTTLCQPDGTWSSPLPECVP 2414
Query: 527 VNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELT 586
V C P + + G Y S A +TC+P + L G +C +G W P+C+
Sbjct: 2415 VECPQPEEIPNGIIDVQGLA-YLSTALYTCKPGFELVGNTTTLCGENGHWLGGKPTCKAI 2473
Query: 587 SCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDC 646
C +P+ G D + T+ + C G +L G L C + G+W D+P+C I C
Sbjct: 2474 ECLKPKEILNGKFSYTDLHYGQTVTYSCNRGFRLEGPSALTCLETGDWDVDAPSCNAIHC 2533
Query: 647 GKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRC 706
+ G +E G++I YSC +++ G +TC EE WS S P C I C
Sbjct: 2534 DSPQPIENGFVE--GADYSYGAIIIYSCFPGFQVAGHAMQTC-EESGWSSSIPTCMPIDC 2590
Query: 707 SDP-----------------IVAEKSIVSV---TGNDRSHGHTLIRTSDNRDVG-----N 741
P E ++ V T + H + +T +N +
Sbjct: 2591 GLPPHIDFGDCTKLKDDQGYFEQEDDMMEVPYVTPHPPYHLGAVAKTWENTKESPATHSS 2650
Query: 742 TYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSN 801
+ G +V Y C GY+++G + C+++G W+G+ P+C ++C P ENG L
Sbjct: 2651 NFLYGTMVSYTCNPGYELLGNPVLICQEDGTWNGSAPSCISIECDLPTAPENG--FLRFT 2708
Query: 802 ATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVV 861
T G+ Y C L G R+C EN WS P C+ I+C P+ + GS +
Sbjct: 2709 ETSMGSAVQYSCKPGHILAGSDLRLCLENRKWSGASPRCEAISCKKPN-PVMNGS---IK 2764
Query: 862 TSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVIS 921
S + +Y+C+ GY L G + RTC W+ P+CIP+DC SP NG+ +
Sbjct: 2765 GSNYTYLSTLYYECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDCSSPPVSANGQ--VR 2822
Query: 922 NGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
F +EY C + G R CL +G WSG P C
Sbjct: 2823 GDEYTFQKEIEYTCNEGFLLEGARSRVCLANGSWSGATPDC 2863
Score = 297 bits (729), Expect = 1e-79
Identities = 180/617 (29%), Positives = 273/617 (44%), Gaps = 49/617 (7%)
Query: 350 PPTCGSPDKLLNTTILGNDYDV-GSRIVYKCPEGHMLLGDKSRHCKKDGFW-SGAPPSCK 407
P +CG P K+ N + + S + Y+C G+ +G C+ + W S +P C
Sbjct: 2178 PVSCGEPPKVENGFLEHTTGRIFESEVRYQCNPGYKSVGSPVFVCQANRHWHSESPLMCV 2237
Query: 408 YVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEA-PRC 466
++CG PI++G + G++ + C E + LVG+ TC G W+ ++ P+C
Sbjct: 2238 PLDCGKPPPIQNGFMK--GENFEVGSKVQFFCNEGYELVGDSSWTCQKSGKWNKKSNPKC 2295
Query: 467 LFDWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKY 526
+ CP+PP + N V + +++C+ GH+L G + + C W+ P CK
Sbjct: 2296 MPAKCPEPPLLENQLVLKELTTEVGVVTFSCKEGHVLQGPSVLKCLPSQQWNDSFPVCKI 2355
Query: 527 VNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELT 586
V C P + + + +GS +++C ++L G +C DG WS +P C
Sbjct: 2356 VLCTPPPLISFGVPIPSSALHFGSTVKYSCVGGFFLRGNSTTLCQPDGTWSSPLPECVPV 2415
Query: 587 SCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDC 646
CP+PE G ++ ST + C+ G +L+G +C ++G W G PTC+ I+C
Sbjct: 2416 ECPQPEEIPNGIIDVQGLAYLSTALYTCKPGFELVGNTTTLCGENGHWLGGKPTCKAIEC 2475
Query: 647 GKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRC 706
K + G + H G + YSC +RL GP TC E W +P C I C
Sbjct: 2476 LKPKEILNGKFSYTD--LHYGQTVTYSCNRGFRLEGPSALTCLETGDWDVDAPSCNAIHC 2533
Query: 707 SDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLST 766
P E V G Y GA++ Y C G++V G ++ T
Sbjct: 2534 DSPQPIENGFVE---------------------GADYSYGAIIIYSCFPGFQVAGHAMQT 2572
Query: 767 CEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRM 826
CE++G WS + PTC +DCG P I+ G T + Y F Q D+ E+ V
Sbjct: 2573 CEESG-WSSSIPTCMPIDCGLPPHIDFGDCTKLKDDQGY----FEQEDDMMEVPYVTPHP 2627
Query: 827 CQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQT 886
G + KE P+ +S G Y C GY L G+
Sbjct: 2628 PYHLGAVAKTWENTKE----SPATH----------SSNFLYGTMVSYTCNPGYELLGNPV 2673
Query: 887 RTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFL 946
C G WNG+ P CI I+C P ENG + + T GS+V+Y C + G L
Sbjct: 2674 LICQEDGTWNGSAPSCISIECDLPTAPENGFLRFT--ETSMGSAVQYSCKPGHILAGSDL 2731
Query: 947 RKCLDDGRWSGEEPSCE 963
R CL++ +WSG P CE
Sbjct: 2732 RLCLENRKWSGASPRCE 2748
Score = 296 bits (727), Expect = 2e-79
Identities = 186/614 (30%), Positives = 267/614 (43%), Gaps = 36/614 (5%)
Query: 352 TCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNC 411
+C P+ ++N +I G++Y S + Y+C G++L G + R C+ D W P C V+C
Sbjct: 2751 SCKKPNPVMNGSIKGSNYTYLSTLYYECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDC 2810
Query: 412 GGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWC 471
+G V + T Y+C E F L G R C G W G P C+ C
Sbjct: 2811 SSPPVSANGQVR--GDEYTFQKEIEYTCNEGFLLEGARSRVCLANGSWSGATPDCVPVRC 2868
Query: 472 PDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGT 531
PP ++N + ++ C G+IL G+ +TC G W P CK VNCG
Sbjct: 2869 ATPPQLANGVTEGLDYGFMKEVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCKPVNCGP 2928
Query: 532 PTIHKGSFVLING-TTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPE 590
P F NG + +G Q+ C P Y L+G C +G WS PSC C
Sbjct: 2929 PEDLAHGFP--NGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCLPCRCST 2986
Query: 591 PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLP 650
P V G + D+ C G KL+G + C+ DG+WS P CE+ CG LP
Sbjct: 2987 P-VIEYGTVNGTDFDCGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHCEHTSCGSLP 3045
Query: 651 TLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPI 710
+P + ++ +VI YSC + Y + G CTE+ WS P CE + C P
Sbjct: 3046 MIPNAFIS--ETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPLSCGSP- 3102
Query: 711 VAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGES-LSTCED 769
S+ + +H TY + VK RC +GY + ++ TC+
Sbjct: 3103 ---PSVANAVATGEAH---------------TYE--SEVKLRCLEGYTMDTDTDTFTCQK 3142
Query: 770 NGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQE 829
+G+W +C C P I + + + + C E + EGV +CQ
Sbjct: 3143 DGRWFPERISCSPKKCPLPENITH--ILVHGDDFSVNRQVSVSCAEGYTFEGVNISVCQL 3200
Query: 830 NGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTC 889
+GTW EPP E P + ++ VV S + YQCE GY L+G++ R C
Sbjct: 3201 DGTW--EPPFSDESCSPVSCGKPESPEHGFVVGSKYTFESTIIYQCEPGYELEGNRERVC 3258
Query: 890 ISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKC 949
QW+G V +C C +P NGK I N +T G +V Y C Y GP C
Sbjct: 3259 QENRQWSGGVAICKETRCETPLEFLNGKADIENRTT--GPNVVYSCNRGYSLEGPSEAHC 3316
Query: 950 LDDGRWSGEEPSCE 963
++G WS P C+
Sbjct: 3317 TENGTWSHPVPLCK 3330
Score = 292 bits (717), Expect = 4e-78
Identities = 180/620 (29%), Positives = 268/620 (43%), Gaps = 50/620 (8%)
Query: 353 CGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCG 412
C P N + + +GS + Y C GH+L G R C ++ WSGA P C+ ++C
Sbjct: 2694 CDLPTAPENGFLRFTETSMGSAVQYSCKPGHILAGSDLRLCLENRKWSGASPRCEAISCK 2753
Query: 413 GLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCP 472
P+ +G + + T+ + Y C + L G RTC D+ WD + P C+ C
Sbjct: 2754 KPNPVMNGSIK--GSNYTYLSTLYYECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDCS 2811
Query: 473 DPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTP 532
PP +N V + + YTC G +L G+ S C G+WSG P C V C TP
Sbjct: 2812 SPPVSANGQVRGDEYTFQKEIEYTCNEGFLLEGARSRVCLANGSWSGATPDCVPVRCATP 2871
Query: 533 TIHKGSFVLINGTT---TYGSIAQ--FTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTS 587
L NG T YG + + F C Y L+GA +L C DG W +IP C+ +
Sbjct: 2872 P------QLANGVTEGLDYGFMKEVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCKPVN 2925
Query: 588 CPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCG 647
C PE + G+ F + I + C G+KL G + C +G WSG SP+C C
Sbjct: 2926 CGPPEDLAHGFPNGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCLPCRC- 2984
Query: 648 KLPTLPYGTMELLNGTT-HLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRC 706
P + YGT +NGT G + C ++L+G TC + QWS P CE C
Sbjct: 2985 STPVIEYGT---VNGTDFDCGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHCEHTSC 3041
Query: 707 SDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLST 766
+ + +S T + + + ++ Y C GY + G S
Sbjct: 3042 GSLPMIPNAFISETSSWKEN---------------------VITYSCRSGYVIQGSSDLI 3080
Query: 767 CEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELE-GVIRR 825
C + G WS P C+ + CG+P + N T A Y + +C E + ++
Sbjct: 3081 CTEKGVWSQPYPVCEPLSCGSPPSVANAVAT--GEAHTYESEVKLRCLEGYTMDTDTDTF 3138
Query: 826 MCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQ 885
CQ++G W E C CP P + + +LV S+ + C GY +G
Sbjct: 3139 TCQKDGRWFPERISCSPKKCPLP----ENITHILVHGDDFSVNRQVSVSCAEGYTFEGVN 3194
Query: 886 TRTCISKGQWNG--TVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVG 943
C G W + C P+ C P + E+G +V S + F S++ Y C Y+ G
Sbjct: 3195 ISVCQLDGTWEPPFSDESCSPVSCGKPESPEHGFVVGSKYT--FESTIIYQCEPGYELEG 3252
Query: 944 PFLRKCLDDGRWSGEEPSCE 963
R C ++ +WSG C+
Sbjct: 3253 NRERVCQENRQWSGGVAICK 3272
Score = 291 bits (714), Expect = 9e-78
Identities = 176/586 (30%), Positives = 255/586 (43%), Gaps = 38/586 (6%)
Query: 372 GSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRTTH 431
G+ + Y C G+ LLG+ C++DG W+G+ PSC + C T E+G + + T+
Sbjct: 2655 GTMVSYTCNPGYELLGNPVLICQEDGTWNGSAPSCISIECDLPTAPENGFLRFTE--TSM 2712
Query: 432 GARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGS 491
G+ YSC+ L G+ R C + W G +PRC C P V N S+ + + S
Sbjct: 2713 GSAVQYSCKPGHILAGSDLRLCLENRKWSGASPRCEAISCKKPNPVMNGSIKGSNYTYLS 2772
Query: 492 LASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTIHKGSFVLINGTTTYGSI 551
Y C+ G++L+G+ TC W P C V+C +P + V T+
Sbjct: 2773 TLYYECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDCSSPPVSANGQVR-GDEYTFQKE 2831
Query: 552 AQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFDYYVHSTIN 611
++TC + L GA VC +G WS P C C P + G E DY +
Sbjct: 2832 IEYTCNEGFLLEGARSRVCLANGSWSGATPDCVPVRCATPPQLANGVTEGLDYGFMKEVT 2891
Query: 612 FHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHL-GSVI 670
FHC G+ L G P L CQ DG W + P C+ ++CG L +G NG + + G I
Sbjct: 2892 FHCHEGYILHGAPKLTCQSDGNWDAEIPLCKPVNCGPPEDLAHG---FPNGFSFIHGGHI 2948
Query: 671 QYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTL 730
QY C Y+L G R C WS SSP C RCS P++ +V G D
Sbjct: 2949 QYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCLPCRCSTPVI---EYGTVNGTD------- 2998
Query: 731 IRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGR 790
D G RI +C KG+K++G S TCE +GQWS P C++ CG+
Sbjct: 2999 ------FDCGKAARI------QCFKGFKLLGLSEITCEADGQWSSGFPHCEHTSCGSLPM 3046
Query: 791 IENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSA 850
I N ++ +++ Y C + ++G +C E G WS P+C+ ++C P +
Sbjct: 3047 IPNAFIS--ETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPLSCGSPPS 3104
Query: 851 QIKAGSGLLVVTSTLSIGGEAHYQCERGYNL-KGHQTRTCISKGQWNGTVPVCIPIDCRS 909
A + + E +C GY + T TC G+W C P C
Sbjct: 3105 VANA----VATGEAHTYESEVKLRCLEGYTMDTDTDTFTCQKDGRWFPERISCSPKKCPL 3160
Query: 910 PGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRW 955
P NI + I++ V C Y G + C DG W
Sbjct: 3161 PENITH--ILVHGDDFSVNRQVSVSCAEGYTFEGVNISVCQLDGTW 3204
Score = 286 bits (701), Expect = 3e-76
Identities = 183/621 (29%), Positives = 267/621 (42%), Gaps = 43/621 (6%)
Query: 349 LPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKY 408
+P C SP N + G++Y I Y C EG +L G +SR C +G WSGA P C
Sbjct: 2806 IPVDCSSPPVSANGQVRGDEYTFQKEIEYTCNEGFLLEGARSRVCLANGSWSGATPDCVP 2865
Query: 409 VNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLF 468
V C + +G +D + C E + L G P+ TC +G WD E P C
Sbjct: 2866 VRCATPPQLANGVTEGLDYGFMK--EVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCKP 2923
Query: 469 DWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVN 528
C P +++ G Y C G+ L G++S C G+WSG PSC
Sbjct: 2924 VNCGPPEDLAHGFPNGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCLPCR 2983
Query: 529 CGTPTIHKGSFVLINGTT-TYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTS 587
C TP I G+ +NGT G A+ C + L G E+ C DG+WS P CE TS
Sbjct: 2984 CSTPVIEYGT---VNGTDFDCGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHCEHTS 3040
Query: 588 CPE-PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDC 646
C P +P+ ++ + + I + C +G+ + G +L+C + G WS P CE + C
Sbjct: 3041 CGSLPMIPN-AFISETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPLSC 3099
Query: 647 GKLPTLPYGTMELLNGTTH-LGSVIQYSCTTNYRL-VGPVRRTCTEEFQWSDSSPRCEEI 704
G P++ + G H S ++ C Y + TC ++ +W C
Sbjct: 3100 GSPPSV---ANAVATGEAHTYESEVKLRCLEGYTMDTDTDTFTCQKDGRWFPERISCSPK 3156
Query: 705 RCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESL 764
+C P ++T H L+ G+ + + V C +GY G ++
Sbjct: 3157 KCPLP-------ENIT-------HILVH-------GDDFSVNRQVSVSCAEGYTFEGVNI 3195
Query: 765 STCEDNGQWSG--TTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGV 822
S C+ +G W + +C V CG P E+G V + S TF +T YQC+ +ELEG
Sbjct: 3196 SVCQLDGTWEPPFSDESCSPVSCGKPESPEHGFV-VGSKYTF-ESTIIYQCEPGYELEGN 3253
Query: 823 IRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLK 882
R+CQEN WS ICKE C P + + + + G Y C RGY+L+
Sbjct: 3254 RERVCQENRQWSGGVAICKETRCETPLEFLNGKADI----ENRTTGPNVVYSCNRGYSLE 3309
Query: 883 GHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRV 942
G C G W+ VP+C P C P I + +S +V C +
Sbjct: 3310 GPSEAHCTENGTWSHPVPLCKPNPCPVPFVIPENAL-LSEKEFYVDQNVSIKCREGFLLQ 3368
Query: 943 GPFLRKCLDDGRWSGEEPSCE 963
G + C D W+ CE
Sbjct: 3369 GHGIITCNPDETWTQTSAKCE 3389
Score = 274 bits (671), Expect = 1e-72
Identities = 176/621 (28%), Positives = 253/621 (40%), Gaps = 46/621 (7%)
Query: 349 LPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKY 408
+P C +P +L N G DY + + C EG++L G C+ DG W P CK
Sbjct: 2864 VPVRCATPPQLANGVTEGLDYGFMKEVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCKP 2923
Query: 409 VNCGGLTPIEDGDVALIDNRT-THGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL 467
VNCG P ED + + HG Y C + L GN R C G W G +P CL
Sbjct: 2924 VNCG---PPEDLAHGFPNGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCL 2980
Query: 468 FDWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYV 527
C P + +V G A C G L G + +TC G WS P C++
Sbjct: 2981 PCRC-STPVIEYGTVNGTDFDCGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHCEHT 3039
Query: 528 NCGTPTIHKGSFVLINGTTTYG-SIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELT 586
+CG+ + +F I+ T+++ ++ ++C Y + G+ +L+C G WS P CE
Sbjct: 3040 SCGSLPMIPNAF--ISETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPL 3097
Query: 587 SCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPN-LVCQQDGEWSGDSPTCEYID 645
SC P + + S + C G+ + + + CQ+DG W + +C
Sbjct: 3098 SCGSPPSVANAVATGEAHTYESEVKLRCLEGYTMDTDTDTFTCQKDGRWFPERISCSPKK 3157
Query: 646 CGKLPTLPYGTMELLNGTTH-LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSD--SSPRCE 702
C P T L++G + + SC Y G C + W S C
Sbjct: 3158 C---PLPENITHILVHGDDFSVNRQVSVSCAEGYTFEGVNISVCQLDGTWEPPFSDESCS 3214
Query: 703 EIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGE 762
+ C P E HG VG+ Y + + Y+CE GY++ G
Sbjct: 3215 PVSCGKPESPE------------HGFV---------VGSKYTFESTIIYQCEPGYELEGN 3253
Query: 763 SLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGV 822
C++N QWSG C+ C P NGK + + T G Y C+ + LEG
Sbjct: 3254 RERVCQENRQWSGGVAICKETRCETPLEFLNGKADIENRTT--GPNVVYSCNRGYSLEGP 3311
Query: 823 IRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLK 882
C ENGTWS P+CK CP P L+ + +C G+ L+
Sbjct: 3312 SEAHCTENGTWSHPVPLCKPNPCPVP---FVIPENALLSEKEFYVDQNVSIKCREGFLLQ 3368
Query: 883 GHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRV 942
GH TC W T C I C P ++EN + +G + Y C S Y
Sbjct: 3369 GHGIITCNPDETWTQTSAKCEKISCGPPAHVENA--IARGVHYQYGDMITYSCYSGYMLE 3426
Query: 943 GPFLRK-CLDDGRWSGEEPSC 962
G FLR CL++G W+ P C
Sbjct: 3427 G-FLRSVCLENGTWT-SPPIC 3445
Score = 266 bits (653), Expect = 2e-70
Identities = 169/600 (28%), Positives = 259/600 (43%), Gaps = 40/600 (6%)
Query: 372 GSRIVYKCPEGHMLLGDKSRHCKKDGFW---SGAP-PSCKYVNCGGLTPIEDGDVALIDN 427
G Y C +G+ L + C G W G P C C + + +
Sbjct: 2017 GDIAFYYCSDGYSLADNSQLLCNAQGKWVPPEGQDMPRCIAHFCEKPPSVSYSILESVSK 2076
Query: 428 -RTTHGARALYSCRENFTLVGNPERTCGDEGIWDGE--APRCLFDWCPDPPAVSNASVTV 484
+ G+ + C E F L + + C G W+ + +C+ C +PP++ N +
Sbjct: 2077 AKFAAGSVVSFKCMEGFVLNTSAKIECMRGGQWNPSPMSIQCIPVRCGEPPSIMNGYASG 2136
Query: 485 NGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTIHKGSFVLING 544
+ + G++ +Y+C G + G TC G WS P+C V+CG P + F+
Sbjct: 2137 SNYSFGAMVAYSCNKGFYIKGEKKSTCEATGQWSSPIPTCHPVSCGEPPKVENGFLEHTT 2196
Query: 545 TTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIP-SCELTSCPEPEVPSGGYMEAFD 603
+ S ++ C P Y G+ VC + W + P C C +P G+M+ +
Sbjct: 2197 GRIFESEVRYQCNPGYKSVGSPVFVCQANRHWHSESPLMCVPLDCGKPPPIQNGFMKGEN 2256
Query: 604 YYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDS-PTCEYIDCGKLPTLPYGTMELLNG 662
+ V S + F C G++L+G+ + CQ+ G+W+ S P C C + P L + L
Sbjct: 2257 FEVGSKVQFFCNEGYELVGDSSWTCQKSGKWNKKSNPKCMPAKCPEPPLLE-NQLVLKEL 2315
Query: 663 TTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGN 722
TT +G V+ +SC + L GP C QW+DS P C+ + C+ P +
Sbjct: 2316 TTEVG-VVTFSCKEGHVLQGPSVLKCLPSQQWNDSFPVCKIVLCTPPPLI---------- 2364
Query: 723 DRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQY 782
S G + + G+ VKY C G+ + G S + C+ +G WS P C
Sbjct: 2365 --SFGVPI--------PSSALHFGSTVKYSCVGGFFLRGNSTTLCQPDGTWSSPLPECVP 2414
Query: 783 VDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKE 842
V+C P I NG + + A Y +TA Y C +EL G +C ENG W P CK
Sbjct: 2415 VECPQPEEIPNGIIDVQGLA--YLSTALYTCKPGFELVGNTTTLCGENGHWLGGKPTCKA 2472
Query: 843 ITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVC 902
I C P + +G T L G Y C RG+ L+G TC+ G W+ P C
Sbjct: 2473 IECLKPKEIL---NGKFSYTD-LHYGQTVTYSCNRGFRLEGPSALTCLETGDWDVDAPSC 2528
Query: 903 IPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
I C SP IENG + +G+ + Y C +Q G ++ C + G WS P+C
Sbjct: 2529 NAIHCDSPQPIENG--FVEGADYSYGAIIIYSCFPGFQVAGHAMQTCEESG-WSSSIPTC 2585
Score = 266 bits (651), Expect = 4e-70
Identities = 165/537 (30%), Positives = 232/537 (43%), Gaps = 42/537 (7%)
Query: 431 HGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAG 490
+G Y+C + L+GNP C ++G W+G AP C+ C P A N + G
Sbjct: 2654 YGTMVSYTCNPGYELLGNPVLICQEDGTWNGSAPSCISIECDLPTAPENGFLRFTETSMG 2713
Query: 491 SLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPT-IHKGSFVLINGTT-TY 548
S Y+C+ GHIL+GS C WSG P C+ ++C P + GS I G+ TY
Sbjct: 2714 SAVQYSCKPGHILAGSDLRLCLENRKWSGASPRCEAISCKKPNPVMNGS---IKGSNYTY 2770
Query: 549 GSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFDYYVHS 608
S + C+P Y LNG E C D W D P C C P V + G + +Y
Sbjct: 2771 LSTLYYECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDCSSPPVSANGQVRGDEYTFQK 2830
Query: 609 TINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGS 668
I + C G L G + VC +G WSG +P C + C P L G E L+
Sbjct: 2831 EIEYTCNEGFLLEGARSRVCLANGSWSGATPDCVPVRCATPPQLANGVTEGLD--YGFMK 2888
Query: 669 VIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGH 728
+ + C Y L G + TC + W P C+ + C P D +HG
Sbjct: 2889 EVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCKPVNCGPP------------EDLAHGF 2936
Query: 729 TLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNP 788
G ++ G ++Y+C GYK+ G S C NG WSG++P+C C P
Sbjct: 2937 ---------PNGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCLPCRCSTP 2987
Query: 789 GRIENGKVTLPSNATFY--GATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCP 846
IE G V N T + G A QC + ++L G+ C+ +G WS P C+ +C
Sbjct: 2988 -VIEYGTV----NGTDFDCGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHCEHTSC- 3041
Query: 847 DPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPID 906
+ + + TS+ Y C GY ++G C KG W+ PVC P+
Sbjct: 3042 --GSLPMIPNAFISETSSWK-ENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPLS 3098
Query: 907 CRSPGNIENGKIVISNGSTLFGSSVEYYCLSQY-QRVGPFLRKCLDDGRWSGEEPSC 962
C SP ++ N V + + + S V+ CL Y C DGRW E SC
Sbjct: 3099 CGSPPSVANA--VATGEAHTYESEVKLRCLEGYTMDTDTDTFTCQKDGRWFPERISC 3153
Score = 248 bits (607), Expect = 8e-65
Identities = 145/505 (28%), Positives = 219/505 (43%), Gaps = 31/505 (6%)
Query: 347 QYLPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSC 406
Q +P CG P ++N G++Y G+ + Y C +G + G+K C+ G WS P+C
Sbjct: 2117 QCIPVRCGEPPSIMNGYASGSNYSFGAMVAYSCNKGFYIKGEKKSTCEATGQWSSPIPTC 2176
Query: 407 KYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAP-R 465
V+CG +E+G + R + Y C + VG+P C W E+P
Sbjct: 2177 HPVSCGEPPKVENGFLEHTTGRIFE-SEVRYQCNPGYKSVGSPVFVCQANRHWHSESPLM 2235
Query: 466 CLFDWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVP-PSC 524
C+ C PP + N + + GS + C G+ L G +S TC G W+ P C
Sbjct: 2236 CVPLDCGKPPPIQNGFMKGENFEVGSKVQFFCNEGYELVGDSSWTCQKSGKWNKKSNPKC 2295
Query: 525 KYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCE 584
C P + + VL TT G + F+C+ + L G L C +W+ P C+
Sbjct: 2296 MPAKCPEPPLLENQLVLKELTTEVG-VVTFSCKEGHVLQGPSVLKCLPSQQWNDSFPVCK 2354
Query: 585 LTSC-PEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEY 643
+ C P P + G + + + ST+ + C G L G +CQ DG WS P C
Sbjct: 2355 IVLCTPPPLISFGVPIPSSALHFGSTVKYSCVGGFFLRGNSTTLCQPDGTWSSPLPECVP 2414
Query: 644 IDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEE 703
++C + +P G ++ + G +L + + Y+C + LVG C E W P C+
Sbjct: 2415 VECPQPEEIPNGIID-VQGLAYLSTAL-YTCKPGFELVGNTTTLCGENGHWLGGKPTCKA 2472
Query: 704 IRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGES 763
I C P S T D +G T V Y C +G+++ G S
Sbjct: 2473 IECLKPKEILNGKFSYT--DLHYGQT-------------------VTYSCNRGFRLEGPS 2511
Query: 764 LSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVI 823
TC + G W P+C + C +P IENG V + YGA Y C +++ G
Sbjct: 2512 ALTCLETGDWDVDAPSCNAIHCDSPQPIENGFVEGADYS--YGAIIIYSCFPGFQVAGHA 2569
Query: 824 RRMCQENGTWSLEPPICKEITCPDP 848
+ C+E+G WS P C I C P
Sbjct: 2570 MQTCEESG-WSSSIPTCMPIDCGLP 2593
Score = 239 bits (586), Expect = 3e-62
Identities = 168/620 (27%), Positives = 258/620 (41%), Gaps = 63/620 (10%)
Query: 352 TCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVN- 410
+CG P L N +D+ GS + Y+C G+ LLGD C +G W+G PSC V+
Sbjct: 1666 SCGVPPPLENGFHSADDFYAGSTVTYQCNNGYYLLGDSRMFCTDNGSWNGVSPSCLDVDE 1725
Query: 411 CG-GLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFD 469
C G E +D + SC +T G + C E +C
Sbjct: 1726 CAVGSDCSEHASCLNVD------GSYICSCVPPYTGDG---KNC-------AEPIKCK-- 1767
Query: 470 WCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNC 529
P P ++S + + G+ +++C+ G+ L G T +TC G W+ + P CK V+C
Sbjct: 1768 -APGNPENGHSSGEI--YTVGAEVTFSCQEGYQLMGVTKITCLESGEWNHLIPYCKAVSC 1824
Query: 530 GTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCP 589
G P I + + T+GS + C Y L G +E C + WS+ P CE C
Sbjct: 1825 GKPAIPENG-CIEELAFTFGSKVTYRCNKGYTLAGDKESSCLANSSWSHSPPVCEPVKCS 1883
Query: 590 EPE-VPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGK 648
PE + +G Y+ + Y+ ST ++ C+ G+ L G + C G W P C + CG+
Sbjct: 1884 SPENINNGKYILSGLTYL-STASYSCDTGYSLQGPSIIECTASGIWDRAPPACHLVFCGE 1942
Query: 649 LPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSD 708
P + + N T + + Y+C Y L G C + +WS S +C + C +
Sbjct: 1943 PPAIKDAVITGNNFT--FRNTVTYTCKEGYTLAGLDTIECLADGKWSRSDQQCLAVSCDE 2000
Query: 709 PIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCE 768
P + + + H L G + Y C GY + S C
Sbjct: 2001 PPIVDHA-------SPETAHRL--------------FGDIAFYYCSDGYSLADNSQLLCN 2039
Query: 769 DNGQW----SGTTPTCQYVDCGNPGRIENGKVTLPSNATF-YGATAFYQCDENWELEGVI 823
G+W P C C P + + S A F G+ ++C E + L
Sbjct: 2040 AQGKWVPPEGQDMPRCIAHFCEKPPSVSYSILESVSKAKFAAGSVVSFKCMEGFVLNTSA 2099
Query: 824 RRMCQENGTWSLEPPI--CKEITCPDPSAQIKA-GSGLLVVTSTLSIGGEAHYQCERGYN 880
+ C G W+ P C + C +P + + SG S S G Y C +G+
Sbjct: 2100 KIECMRGGQWNPSPMSIQCIPVRCGEPPSIMNGYASG-----SNYSFGAMVAYSCNKGFY 2154
Query: 881 LKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQ 940
+KG + TC + GQW+ +P C P+ C P +ENG + + G +F S V Y C Y+
Sbjct: 2155 IKGEKKSTCEATGQWSSPIPTCHPVSCGEPPKVENGFLEHTTG-RIFESEVRYQCNPGYK 2213
Query: 941 RVGPFLRKCLDDGRWSGEEP 960
VG + C + W E P
Sbjct: 2214 SVGSPVFVCQANRHWHSESP 2233
Score = 234 bits (572), Expect = 1e-60
Identities = 159/605 (26%), Positives = 252/605 (41%), Gaps = 62/605 (10%)
Query: 368 DYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDN 427
D GS++ C G L+G+ ++C G W+ P C+ ++CG P+E+G + D
Sbjct: 1624 DLKPGSKVNLFCDPGFQLVGNPVQYCLNQGQWTQPLPHCERISCGVPPPLENGFHSADDF 1683
Query: 428 RTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL-FDWCPDPPAVSNASVTVNG 486
G+ Y C + L+G+ C D G W+G +P CL D C
Sbjct: 1684 YA--GSTVTYQCNNGYYLLGDSRMFCTDNGSWNGVSPSCLDVDEC--------------- 1726
Query: 487 HKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSC-KYVNCGTPTIHKGSFVLINGT 545
++ S E+ L+ S C+ ++G +C + + C P +
Sbjct: 1727 ----AVGSDCSEHASCLNVDGSYICSCVPPYTGDGKNCAEPIKCKAPGNPENGH-SSGEI 1781
Query: 546 TTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFDYY 605
T G+ F+C+ Y L G ++ C G+W++ IP C+ SC +P +P G +E +
Sbjct: 1782 YTVGAEVTFSCQEGYQLMGVTKITCLESGEWNHLIPYCKAVSCGKPAIPENGCIEELAFT 1841
Query: 606 VHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTH 665
S + + C G+ L G+ C + WS P CE + C + G +L+G T+
Sbjct: 1842 FGSKVTYRCNKGYTLAGDKESSCLANSSWSHSPPVCEPVKCSSPENINNGKY-ILSGLTY 1900
Query: 666 LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRS 725
L S YSC T Y L GP CT W + P C + C +P + ++++
Sbjct: 1901 L-STASYSCDTGYSLQGPSIIECTASGIWDRAPPACHLVFCGEPPAIKDAVIT------- 1952
Query: 726 HGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDC 785
GN + V Y C++GY + G C +G+WS + C V C
Sbjct: 1953 --------------GNNFTFRNTVTYTCKEGYTLAGLDTIECLADGKWSRSDQQCLAVSC 1998
Query: 786 GNPGRIENGKVTLPSNA-TFYGATAFYQCDENWELEGVIRRMCQENGTW----SLEPPIC 840
P +++ P A +G AFY C + + L + +C G W + P C
Sbjct: 1999 DEPPIVDHAS---PETAHRLFGDIAFYYCSDGYSLADNSQLLCNAQGKWVPPEGQDMPRC 2055
Query: 841 KEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVP 900
C P + + V + + G ++C G+ L C+ GQWN + P
Sbjct: 2056 IAHFCEKPPS-VSYSILESVSKAKFAAGSVVSFKCMEGFVLNTSAKIECMRGGQWNPS-P 2113
Query: 901 V---CIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSG 957
+ CIP+ C P +I NG SN S FG+ V Y C + G C G+WS
Sbjct: 2114 MSIQCIPVRCGEPPSIMNGYASGSNYS--FGAMVAYSCNKGFYIKGEKKSTCEATGQWSS 2171
Query: 958 EEPSC 962
P+C
Sbjct: 2172 PIPTC 2176
Score = 165 bits (402), Expect = 6e-40
Identities = 124/483 (25%), Positives = 191/483 (39%), Gaps = 49/483 (10%)
Query: 352 TCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNC 411
+CGS + N I + I Y C G+++ G C + G WS P C+ ++C
Sbjct: 3040 SCGSLPMIPNAFISETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPLSC 3099
Query: 412 GGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPER-TCGDEGIWDGEAPRCLFDW 470
G +P + T+ + C E +T+ + + TC +G W E C
Sbjct: 3100 G--SPPSVANAVATGEAHTYESEVKLRCLEGYTMDTDTDTFTCQKDGRWFPERISCSPKK 3157
Query: 471 CPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPP----SCKY 526
CP P +++ V + S +C G+ G C L G W PP SC
Sbjct: 3158 CPLPENITHILVHGDDFSVNRQVSVSCAEGYTFEGVNISVCQLDGTWE--PPFSDESCSP 3215
Query: 527 VNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELT 586
V+CG P + FV + T+ S + CEP Y L G E VC + +WS + C+ T
Sbjct: 3216 VSCGKPESPEHGFV-VGSKYTFESTIIYQCEPGYELEGNRERVCQENRQWSGGVAICKET 3274
Query: 587 SCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDC 646
C P G + + + + C G+ L G C ++G WS P C+ C
Sbjct: 3275 RCETPLEFLNGKADIENRTTGPNVVYSCNRGYSLEGPSEAHCTENGTWSHPVPLCKPNPC 3334
Query: 647 GKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRC 706
+P + L ++ + C + L G TC + W+ +S +CE+I C
Sbjct: 3335 PVPFVIPENAL-LSEKEFYVDQNVSIKCREGFLLQGHGIITCNPDETWTQTSAKCEKISC 3393
Query: 707 SDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLST 766
P E +I G Y+ G ++ Y C GY + G S
Sbjct: 3394 GPPAHVENAIAR---------------------GVHYQYGDMITYSCYSGYMLEGFLRSV 3432
Query: 767 CEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRM 826
C +NG W+ + P C+ V C P +NG + NA C E W + R+
Sbjct: 3433 CLENGTWT-SPPICRAV-CRFP--CQNGGICQRPNAC--------SCPEGW-----MGRL 3475
Query: 827 CQE 829
C+E
Sbjct: 3476 CEE 3478
Score = 153 bits (371), Expect = 3e-36
Identities = 103/369 (27%), Positives = 145/369 (39%), Gaps = 13/369 (3%)
Query: 345 ICQYLPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRH-CKKDGFWSGAP 403
+C+ P +CGSP + N G + S + +C EG+ + D C+KDG W
Sbjct: 3093 VCE--PLSCGSPPSVANAVATGEAHTYESEVKLRCLEGYTMDTDTDTFTCQKDGRWFPER 3150
Query: 404 PSCKYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDG-- 461
SC C P + + + + + SC E +T G C +G W+
Sbjct: 3151 ISCSPKKCP--LPENITHILVHGDDFSVNRQVSVSCAEGYTFEGVNISVCQLDGTWEPPF 3208
Query: 462 EAPRCLFDWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVP 521
C C P + + V + + S Y CE G+ L G+ C WSG
Sbjct: 3209 SDESCSPVSCGKPESPEHGFVVGSKYTFESTIIYQCEPGYELEGNRERVCQENRQWSGGV 3268
Query: 522 PSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIP 581
CK C TP I TT G ++C Y L G E C +G WS+ +P
Sbjct: 3269 AICKETRCETPLEFLNGKADIENRTT-GPNVVYSCNRGYSLEGPSEAHCTENGTWSHPVP 3327
Query: 582 SCELTSCPEPEV-PSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPT 640
C+ CP P V P + ++YV ++ C G L G + C D W+ S
Sbjct: 3328 LCKPNPCPVPFVIPENALLSEKEFYVDQNVSIKCREGFLLQGHGIITCNPDETWTQTSAK 3387
Query: 641 CEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPR 700
CE I CG P G +I YSC + Y L G +R C E W+ S P
Sbjct: 3388 CEKISCG--PPAHVENAIARGVHYQYGDMITYSCYSGYMLEGFLRSVCLENGTWT-SPPI 3444
Query: 701 CEEIRCSDP 709
C + C P
Sbjct: 3445 CRAV-CRFP 3452
Score = 128 bits (309), Expect = 1e-28
Identities = 100/347 (28%), Positives = 146/347 (42%), Gaps = 38/347 (10%)
Query: 644 IDCGKLPTLPYGTMELLNGTTHL--GSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRC 701
I C P L L + L GS + C ++LVG + C + QW+ P C
Sbjct: 1603 IFCSDCPRLGGSVPHLRTASEDLKPGSKVNLFCDPGFQLVGNPVQYCLNQGQWTQPLPHC 1662
Query: 702 EEIRCSDPIVAEKSIVSV----TGNDRSH----GHTLIRTSDN--RDVG--NTYRIGALV 749
E I C P E S G+ ++ G+ L+ S D G N L
Sbjct: 1663 ERISCGVPPPLENGFHSADDFYAGSTVTYQCNNGYYLLGDSRMFCTDNGSWNGVSPSCLD 1722
Query: 750 KYRCEKG---------YKVIGESLSTCEDNGQWSGTTPTC-QYVDCGNPGRIENGKVTLP 799
C G V G + +C ++G C + + C PG ENG
Sbjct: 1723 VDECAVGSDCSEHASCLNVDGSYICSCVP--PYTGDGKNCAEPIKCKAPGNPENGH---- 1776
Query: 800 SNATFY--GATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSG 857
S+ Y GA + C E ++L GV + C E+G W+ P CK ++C P+
Sbjct: 1777 SSGEIYTVGAEVTFSCQEGYQLMGVTKITCLESGEWNHLIPYCKAVSCGKPAIPENGCIE 1836
Query: 858 LLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGK 917
L T G + Y+C +GY L G + +C++ W+ + PVC P+ C SP NI NGK
Sbjct: 1837 ELAFT----FGSKVTYRCNKGYTLAGDKESSCLANSSWSHSPPVCEPVKCSSPENINNGK 1892
Query: 918 IVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCEL 964
++S G T + S+ Y C + Y GP + +C G W P+C L
Sbjct: 1893 YILS-GLT-YLSTASYSCDTGYSLQGPSIIECTASGIWDRAPPACHL 1937
Score = 77.4 bits (182), Expect = 3e-13
Identities = 44/163 (26%), Positives = 68/163 (41%), Gaps = 6/163 (3%)
Query: 752 RCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFY 811
RC G+ ++G S+ C NG WSG+ C+ C + + ++G ++ + Y T
Sbjct: 382 RCHPGFDLVGSSIILCLPNGLWSGSESYCRVRTCPHLRQPKHGHISCSTREMLYKTTCLV 441
Query: 812 QCDENWELEGVIRRMCQENGTWSLEPPICKEITCPD---PSAQIKAGSGLLVVTSTLSIG 868
CDE + LEG + CQ N W P C E C P I + G
Sbjct: 442 ACDEGYRLEGSDKLTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISPHN--CGKQPAKFG 499
Query: 869 GEAHYQCERGYNLKG-HQTRTCISKGQWNGTVPVCIPIDCRSP 910
+ C +G+ L G + C + G+WN V + D +P
Sbjct: 500 TICYVSCRQGFILSGVKEMLRCTTSGKWNVGVQAAVCKDVEAP 542
Score = 76.6 bits (180), Expect = 5e-13
Identities = 47/196 (23%), Positives = 76/196 (38%), Gaps = 7/196 (3%)
Query: 405 SCKYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAP 464
+C+ V+C L P E+G A C F LVG+ C G+W G
Sbjct: 349 TCELVHCPALKPPENGYFIQNTCNNHFNAACGVRCHPGFDLVGSSIILCLPNGLWSGSES 408
Query: 465 RCLFDWCPD--PPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPP 522
C CP P + S + + C+ G+ L GS +TC W G P
Sbjct: 409 YCRVRTCPHLRQPKHGHISCSTREMLYKTTCLVACDEGYRLEGSDKLTCQGNSQWDGPEP 468
Query: 523 SCKYVNCGTPTIHKGSFVLING----TTTYGSIAQFTCEPDYWLNGAEELV-CNRDGKWS 577
C +C T + K + + +G+I +C + L+G +E++ C GKW+
Sbjct: 469 RCVERHCSTFQMPKDVIISPHNCGKQPAKFGTICYVSCRQGFILSGVKEMLRCTTSGKWN 528
Query: 578 YDIPSCELTSCPEPEV 593
+ + P++
Sbjct: 529 VGVQAAVCKDVEAPQI 544
Score = 74.1 bits (174), Expect = 2e-12
Identities = 46/158 (29%), Positives = 68/158 (43%), Gaps = 8/158 (5%)
Query: 378 KCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRTTHGARALY 437
+C G L+G C +G WSG+ C+ C L + G ++ + L
Sbjct: 382 RCHPGFDLVGSSIILCLPNGLWSGSESYCRVRTCPHLRQPKHGHISCSTREMLYKTTCLV 441
Query: 438 SCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWC-----PDPPAVSNASVTVNGHKAGSL 492
+C E + L G+ + TC WDG PRC+ C P +S + K G++
Sbjct: 442 ACDEGYRLEGSDKLTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISPHNCGKQPAKFGTI 501
Query: 493 ASYTCENGHILSG-STSVTCTLGGAWS-GVPPS-CKYV 527
+C G ILSG + CT G W+ GV + CK V
Sbjct: 502 CYVSCRQGFILSGVKEMLRCTTSGKWNVGVQAAVCKDV 539
Score = 72.5 bits (170), Expect = 7e-12
Identities = 43/155 (27%), Positives = 64/155 (41%), Gaps = 4/155 (2%)
Query: 566 EELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYM--EAFDYYVHSTINFHCEAGHKLIGE 623
E+ VC R+G + +CEL CP + P GY + + ++ C G L+G
Sbjct: 335 EDCVC-REG-YRASGQTCELVHCPALKPPENGYFIQNTCNNHFNAACGVRCHPGFDLVGS 392
Query: 624 PNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGP 683
++C +G WSG C C L +G + + +C YRL G
Sbjct: 393 SIILCLPNGLWSGSESYCRVRTCPHLRQPKHGHISCSTREMLYKTTCLVACDEGYRLEGS 452
Query: 684 VRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVS 718
+ TC QW PRC E CS + + I+S
Sbjct: 453 DKLTCQGNSQWDGPEPRCVERHCSTFQMPKDVIIS 487
Score = 72.1 bits (169), Expect = 1e-11
Identities = 39/122 (31%), Positives = 57/122 (46%), Gaps = 2/122 (1%)
Query: 841 KEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVP 900
K I C D + L + L G + + C+ G+ L G+ + C+++GQW +P
Sbjct: 1601 KSIFCSDCPRLGGSVPHLRTASEDLKPGSKVNLFCDPGFQLVGNPVQYCLNQGQWTQPLP 1660
Query: 901 VCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEP 960
C I C P +ENG S GS+V Y C + Y +G C D+G W+G P
Sbjct: 1661 HCERISCGVPPPLENG--FHSADDFYAGSTVTYQCNNGYYLLGDSRMFCTDNGSWNGVSP 1718
Query: 961 SC 962
SC
Sbjct: 1719 SC 1720
Score = 63.7 bits (148), Expect = 3e-09
Identities = 47/206 (22%), Positives = 78/206 (37%), Gaps = 8/206 (3%)
Query: 498 ENGHILSGSTSVT-CTLGGAWSGVPPSCKYVNC-GTPTIHKGSFVLINGTTTYGSIAQFT 555
EN GSTS C + +C+ V+C G F+ + +
Sbjct: 323 ENHTSPPGSTSPEDCVCREGYRASGQTCELVHCPALKPPENGYFIQNTCNNHFNAACGVR 382
Query: 556 CEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAF--DYYVHSTINFH 613
C P + L G+ ++C +G WS C + +CP P G++ + +T
Sbjct: 383 CHPGFDLVGSSIILCLPNGLWSGSESYCRVRTCPHLRQPKHGHISCSTREMLYKTTCLVA 442
Query: 614 CEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCG--KLP-TLPYGTMELLNGTTHLGSVI 670
C+ G++L G L CQ + +W G P C C ++P + G++
Sbjct: 443 CDEGYRLEGSDKLTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISPHNCGKQPAKFGTIC 502
Query: 671 QYSCTTNYRLVGPVRR-TCTEEFQWS 695
SC + L G CT +W+
Sbjct: 503 YVSCRQGFILSGVKEMLRCTTSGKWN 528
Score = 60.9 bits (141), Expect = 2e-08
Identities = 48/194 (24%), Positives = 73/194 (37%), Gaps = 8/194 (4%)
Query: 767 CEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRM 826
C + + SG T C+ V C ENG + + A +C ++L G +
Sbjct: 339 CREGYRASGQT--CELVHCPALKPPENGYFIQNTCNNHFNAACGVRCHPGFDLVGSSIIL 396
Query: 827 CQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQT 886
C NG WS C+ TCP Q K G + T + C+ GY L+G
Sbjct: 397 CLPNGLWSGSESYCRVRTCPH-LRQPKHGH-ISCSTREMLYKTTCLVACDEGYRLEGSDK 454
Query: 887 RTCISKGQWNGTVPVCIPIDC---RSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVG 943
TC QW+G P C+ C + P ++ FG+ C + G
Sbjct: 455 LTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISPHNCGKQPAKFGTICYVSCRQGFILSG 514
Query: 944 -PFLRKCLDDGRWS 956
+ +C G+W+
Sbjct: 515 VKEMLRCTTSGKWN 528
Score = 46.0 bits (104), Expect = 7e-04
Identities = 23/89 (25%), Positives = 37/89 (41%)
Query: 874 QCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEY 933
+C G++L G C+ G W+G+ C C ++G I S L+ ++
Sbjct: 382 RCHPGFDLVGSSIILCLPNGLWSGSESYCRVRTCPHLRQPKHGHISCSTREMLYKTTCLV 441
Query: 934 YCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
C Y+ G C + +W G EP C
Sbjct: 442 ACDEGYRLEGSDKLTCQGNSQWDGPEPRC 470
Score = 46.0 bits (104), Expect = 7e-04
Identities = 19/57 (33%), Positives = 27/57 (47%), Gaps = 3/57 (5%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
CG PA+P N + E G+ Y C++GY L G ++ C W+ PP C
Sbjct: 1824 CGKPAIPENGCIE---ELAFTFGSKVTYRCNKGYTLAGDKESSCLANSSWSHSPPVC 1877
Score = 42.3 bits (95), Expect = 0.009
Identities = 22/61 (36%), Positives = 26/61 (42%), Gaps = 3/61 (4%)
Query: 1 RCGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGT 60
RC P N + I EN G VY C+ GY L G + CT G W+ P C
Sbjct: 3275 RCETPLEFLNGKADI---ENRTTGPNVVYSCNRGYSLEGPSEAHCTENGTWSHPVPLCKP 3331
Query: 61 N 61
N
Sbjct: 3332 N 3332
Score = 40.3 bits (90), Expect = 0.037
Identities = 17/52 (32%), Positives = 24/52 (46%)
Query: 7 VPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
VPP + ++ AG+ Y+C+ GY L G + CT G W P C
Sbjct: 1669 VPPPLENGFHSADDFYAGSTVTYQCNNGYYLLGDSRMFCTDNGSWNGVSPSC 1720
Score = 40.3 bits (90), Expect = 0.037
Identities = 23/67 (34%), Positives = 30/67 (44%), Gaps = 4/67 (5%)
Query: 14 SIPNEENIVAG----TIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTNVAFRKPAN 69
+I N + I++G + A Y CD GY L G ECT G W PP C PA
Sbjct: 1887 NINNGKYILSGLTYLSTASYSCDTGYSLQGPSIIECTASGIWDRAPPACHLVFCGEPPAI 1946
Query: 70 QSTTVRG 76
+ + G
Sbjct: 1947 KDAVITG 1953
Score = 39.1 bits (87), Expect = 0.085
Identities = 22/68 (32%), Positives = 29/68 (42%), Gaps = 4/68 (5%)
Query: 1 RCGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGT 60
+C P P N S E G + C EGY+L G + C G+W P+C
Sbjct: 1765 KCKAPGNPENGHSS---GEIYTVGAEVTFSCQEGYQLMGVTKITCLESGEWNHLIPYCKA 1821
Query: 61 NVAFRKPA 68
V+ KPA
Sbjct: 1822 -VSCGKPA 1828
Score = 38.7 bits (86), Expect = 0.11
Identities = 19/78 (24%), Positives = 34/78 (43%)
Query: 889 CISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRK 948
C+ + + + C + C + ENG + + + F ++ C + VG +
Sbjct: 337 CVCREGYRASGQTCELVHCPALKPPENGYFIQNTCNNHFNAACGVRCHPGFDLVGSSIIL 396
Query: 949 CLDDGRWSGEEPSCELAT 966
CL +G WSG E C + T
Sbjct: 397 CLPNGLWSGSESYCRVRT 414
Score = 37.5 bits (83), Expect = 0.26
Identities = 23/77 (29%), Positives = 29/77 (37%), Gaps = 7/77 (9%)
Query: 8 PPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTNVAFRKP 67
P + PN + + G Y+C GY+L G R C G W+ P C P
Sbjct: 2929 PEDLAHGFPNGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSC-------LP 2981
Query: 68 ANQSTTVRGGAAANGND 84
ST V NG D
Sbjct: 2982 CRCSTPVIEYGTVNGTD 2998
Score = 37.1 bits (82), Expect = 0.34
Identities = 16/58 (27%), Positives = 26/58 (44%), Gaps = 3/58 (5%)
Query: 1 RCGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
RCG P P+ + N G + Y C++G+ + G ++ C G W+ P C
Sbjct: 2122 RCGEP---PSIMNGYASGSNYSFGAMVAYSCNKGFYIKGEKKSTCEATGQWSSPIPTC 2176
Score = 37.1 bits (82), Expect = 0.34
Identities = 21/57 (36%), Positives = 26/57 (45%), Gaps = 3/57 (5%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C P V N +V +E I Y C+EG+ L GAR R C G W+ P C
Sbjct: 2810 CSSPPVSANGQVR--GDEYTFQKEIE-YTCNEGFLLEGARSRVCLANGSWSGATPDC 2863
Score = 35.9 bits (79), Expect = 0.79
Identities = 17/48 (35%), Positives = 22/48 (45%)
Query: 29 YECDEGYELFGARQRECTLRGDWTLEPPFCGTNVAFRKPANQSTTVRG 76
YECD GY L G +R C +W + P C P + + VRG
Sbjct: 2776 YECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDCSSPPVSANGQVRG 2823
Score = 34.7 bits (76), Expect = 1.8
Identities = 15/42 (35%), Positives = 19/42 (45%)
Query: 17 NEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
+ N + GT+ Y C+ GYEL G C G W P C
Sbjct: 2648 HSSNFLYGTMVSYTCNPGYELLGNPVLICQEDGTWNGSAPSC 2689
Score = 34.7 bits (76), Expect = 1.8
Identities = 21/57 (36%), Positives = 24/57 (42%), Gaps = 4/57 (7%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
CG PA NA I + G + Y C GY L G + C G WT PP C
Sbjct: 3393 CGPPAHVENA---IARGVHYQYGDMITYSCYSGYMLEGFLRSVCLENGTWT-SPPIC 3445
Score = 34.3 bits (75), Expect = 2.4
Identities = 18/57 (31%), Positives = 23/57 (40%), Gaps = 1/57 (1%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C H P + +S E + T V CDEGY L G+ + C W P C
Sbjct: 415 CPHLRQPKHGHISCSTREMLYKTTCLV-ACDEGYRLEGSDKLTCQGNSQWDGPEPRC 470
Score = 34.3 bits (75), Expect = 2.4
Identities = 18/57 (31%), Positives = 26/57 (45%), Gaps = 3/57 (5%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
CG + PNA +S E + + Y C GY + G+ CT +G W+ P C
Sbjct: 3041 CGSLPMIPNAFIS---ETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVC 3094
Score = 34.3 bits (75), Expect = 2.4
Identities = 18/51 (35%), Positives = 25/51 (49%), Gaps = 3/51 (5%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWT 52
CG P P + V + TI +Y+C+ GYEL G R+R C W+
Sbjct: 3218 CGKPESPEHGFVV--GSKYTFESTI-IYQCEPGYELEGNRERVCQENRQWS 3265
Score = 33.5 bits (73), Expect = 4.2
Identities = 12/35 (34%), Positives = 16/35 (45%)
Query: 24 GTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
G Y C+ G+ L G C GDW ++ P C
Sbjct: 2494 GQTVTYSCNRGFRLEGPSALTCLETGDWDVDAPSC 2528
Score = 33.5 bits (73), Expect = 4.2
Identities = 13/30 (43%), Positives = 16/30 (53%)
Query: 29 YECDEGYELFGARQRECTLRGDWTLEPPFC 58
+ C EGY L GA + C G+W E P C
Sbjct: 2892 FHCHEGYILHGAPKLTCQSDGNWDAEIPLC 2921
Score = 33.1 bits (72), Expect = 5.6
Identities = 17/49 (34%), Positives = 22/49 (44%), Gaps = 2/49 (4%)
Query: 8 PPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPP 56
PP + P + + G IA Y C +GY L Q C +G W PP
Sbjct: 2001 PPIVDHASPETAHRLFGDIAFYYCSDGYSLADNSQLLCNAQGKWV--PP 2047
Score = 33.1 bits (72), Expect = 5.6
Identities = 15/44 (34%), Positives = 19/44 (43%)
Query: 8 PPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDW 51
PP + EN G+ + C+EGYEL G C G W
Sbjct: 2244 PPPIQNGFMKGENFEVGSKVQFFCNEGYELVGDSSWTCQKSGKW 2287
Score = 32.7 bits (71), Expect = 7.4
Identities = 15/51 (29%), Positives = 19/51 (37%)
Query: 8 PPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
PP + ++ N Y C EGY L G EC G W+ C
Sbjct: 1943 PPAIKDAVITGNNFTFRNTVTYTCKEGYTLAGLDTIECLADGKWSRSDQQC 1993
>AL158158-3|CAI14068.1| 3548|Homo sapiens sushi, von Willebrand factor
type A, EGF and pentraxin domain containing 1 protein.
Length = 3548
Score = 313 bits (769), Expect = 2e-84
Identities = 187/624 (29%), Positives = 280/624 (44%), Gaps = 40/624 (6%)
Query: 350 PPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYV 409
P C +P N G Y VG+ + + C EG+ L+G C + G W+ P CK V
Sbjct: 1763 PIKCKAPGNPENGHSSGEIYTVGAEVTFSCQEGYQLMGVTKITCLESGEWNHLIPYCKAV 1822
Query: 410 NCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFD 469
+CG E+G + + T G++ Y C + +TL G+ E +C W P C
Sbjct: 1823 SCGKPAIPENGCIEEL--AFTFGSKVTYRCNKGYTLAGDKESSCLANSSWSHSPPVCEPV 1880
Query: 470 WCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNC 529
C P ++N ++G S ASY+C+ G+ L G + + CT G W PP+C V C
Sbjct: 1881 KCSSPENINNGKYILSGLTYLSTASYSCDTGYSLQGPSIIECTASGIWDRAPPACHLVFC 1940
Query: 530 GTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCP 589
G P K + V+ T+ + +TC+ Y L G + + C DGKWS C SC
Sbjct: 1941 GEPPAIKDA-VITGNNFTFRNTVTYTCKEGYTLAGLDTIECLADGKWSRSDQQCLAVSCD 1999
Query: 590 EPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEW----SGDSPTCEYID 645
EP + E ++C G+ L L+C G+W D P C
Sbjct: 2000 EPPIVDHASPETAHRLFGDIAFYYCSDGYSLADNSQLLCNAQGKWVPPEGQDMPRCIAHF 2059
Query: 646 CGKLPTLPYGTMELLNGTTH-LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDS--SPRCE 702
C K P++ Y +E ++ GSV+ + C + L + C QW+ S S +C
Sbjct: 2060 CEKPPSVSYSILESVSKAKFAAGSVVSFKCMEGFVLNTSAKIECMRGGQWNPSPMSIQCI 2119
Query: 703 EIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGE 762
+RC +P SI+ +G+ G+ Y GA+V Y C KG+ + GE
Sbjct: 2120 PVRCGEP----PSIM--------NGYA---------SGSNYSFGAMVAYSCNKGFYIKGE 2158
Query: 763 SLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGV 822
STCE GQWS PTC V CG P ++ENG + + F YQC+ ++ G
Sbjct: 2159 KKSTCEATGQWSSPIPTCHPVSCGEPPKVENGFLEHTTGRIFESEVR-YQCNPGYKSVGS 2217
Query: 823 IRRMCQENGTWSLEPPI-CKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNL 881
+CQ N W E P+ C + C P I+ G + +G + + C GY L
Sbjct: 2218 PVFVCQANRHWHSESPLMCVPLDCGKP-PPIQNG---FMKGENFEVGSKVQFFCNEGYEL 2273
Query: 882 KGHQTRTCISKGQWN-GTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQ 940
G + TC G+WN + P C+P C P +EN ++V+ +T G V + C +
Sbjct: 2274 VGDSSWTCQKSGKWNKKSNPKCMPAKCPEPPLLEN-QLVLKELTTEVG-VVTFSCKEGHV 2331
Query: 941 RVGPFLRKCLDDGRWSGEEPSCEL 964
GP + KCL +W+ P C++
Sbjct: 2332 LQGPSVLKCLPSQQWNDSFPVCKI 2355
Score = 312 bits (766), Expect = 5e-84
Identities = 187/641 (29%), Positives = 283/641 (44%), Gaps = 41/641 (6%)
Query: 349 LPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSG-APPSCK 407
+P CG P + N + G +++VGS++ + C EG+ L+GD S C+K G W+ + P C
Sbjct: 2237 VPLDCGKPPPIQNGFMKGENFEVGSKVQFFCNEGYELVGDSSWTCQKSGKWNKKSNPKCM 2296
Query: 408 YVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL 467
C P+ + + L + T G +SC+E L G C W+ P C
Sbjct: 2297 PAKCPE-PPLLENQLVLKELTTEVGV-VTFSCKEGHVLQGPSVLKCLPSQQWNDSFPVCK 2354
Query: 468 FDWCPDPPAVS-NASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKY 526
C PP +S + + GS Y+C G L G+++ C G WS P C
Sbjct: 2355 IVLCTPPPLISFGVPIPSSALHFGSTVKYSCVGGFFLRGNSTTLCQPDGTWSSPLPECVP 2414
Query: 527 VNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELT 586
V C P + + G Y S A +TC+P + L G +C +G W P+C+
Sbjct: 2415 VECPQPEEIPNGIIDVQGLA-YLSTALYTCKPGFELVGNTTTLCGENGHWLGGKPTCKAI 2473
Query: 587 SCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDC 646
C +P+ G D + T+ + C G +L G L C + G+W D+P+C I C
Sbjct: 2474 ECLKPKEILNGKFSYTDLHYGQTVTYSCNRGFRLEGPSALTCLETGDWDVDAPSCNAIHC 2533
Query: 647 GKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRC 706
+ G +E G++I YSC +++ G +TC EE WS S P C I C
Sbjct: 2534 DSPQPIENGFVE--GADYSYGAIIIYSCFPGFQVAGHAMQTC-EESGWSSSIPTCMPIDC 2590
Query: 707 SDP-----------------IVAEKSIVSV---TGNDRSHGHTLIRTSDNRDVG-----N 741
P E ++ V T + H + +T +N +
Sbjct: 2591 GLPPHIDFGDCTKLKDDQGYFEQEDDMMEVPYVTPHPPYHLGAVAKTWENTKESPATHSS 2650
Query: 742 TYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSN 801
+ G +V Y C GY+++G + C+++G W+G+ P+C ++C P ENG L
Sbjct: 2651 NFLYGTMVSYTCNPGYELLGNPVLICQEDGTWNGSAPSCISIECDLPTAPENG--FLRFT 2708
Query: 802 ATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVV 861
T G+ Y C L G R+C EN WS P C+ I+C P+ + GS +
Sbjct: 2709 ETSMGSAVQYSCKPGHILAGSDLRLCLENRKWSGASPRCEAISCKKPN-PVMNGS---IK 2764
Query: 862 TSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVIS 921
S + +Y+C+ GY L G + RTC W+ P+CIP+DC SP NG+ +
Sbjct: 2765 GSNYTYLSTLYYECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDCSSPPVSANGQ--VR 2822
Query: 922 NGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
F +EY C + G R CL +G WSG P C
Sbjct: 2823 GDEYTFQKEIEYTCNEGFLLEGARSRVCLANGSWSGATPDC 2863
Score = 297 bits (729), Expect = 1e-79
Identities = 180/617 (29%), Positives = 273/617 (44%), Gaps = 49/617 (7%)
Query: 350 PPTCGSPDKLLNTTILGNDYDV-GSRIVYKCPEGHMLLGDKSRHCKKDGFW-SGAPPSCK 407
P +CG P K+ N + + S + Y+C G+ +G C+ + W S +P C
Sbjct: 2178 PVSCGEPPKVENGFLEHTTGRIFESEVRYQCNPGYKSVGSPVFVCQANRHWHSESPLMCV 2237
Query: 408 YVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEA-PRC 466
++CG PI++G + G++ + C E + LVG+ TC G W+ ++ P+C
Sbjct: 2238 PLDCGKPPPIQNGFMK--GENFEVGSKVQFFCNEGYELVGDSSWTCQKSGKWNKKSNPKC 2295
Query: 467 LFDWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKY 526
+ CP+PP + N V + +++C+ GH+L G + + C W+ P CK
Sbjct: 2296 MPAKCPEPPLLENQLVLKELTTEVGVVTFSCKEGHVLQGPSVLKCLPSQQWNDSFPVCKI 2355
Query: 527 VNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELT 586
V C P + + + +GS +++C ++L G +C DG WS +P C
Sbjct: 2356 VLCTPPPLISFGVPIPSSALHFGSTVKYSCVGGFFLRGNSTTLCQPDGTWSSPLPECVPV 2415
Query: 587 SCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDC 646
CP+PE G ++ ST + C+ G +L+G +C ++G W G PTC+ I+C
Sbjct: 2416 ECPQPEEIPNGIIDVQGLAYLSTALYTCKPGFELVGNTTTLCGENGHWLGGKPTCKAIEC 2475
Query: 647 GKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRC 706
K + G + H G + YSC +RL GP TC E W +P C I C
Sbjct: 2476 LKPKEILNGKFSYTD--LHYGQTVTYSCNRGFRLEGPSALTCLETGDWDVDAPSCNAIHC 2533
Query: 707 SDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLST 766
P E V G Y GA++ Y C G++V G ++ T
Sbjct: 2534 DSPQPIENGFVE---------------------GADYSYGAIIIYSCFPGFQVAGHAMQT 2572
Query: 767 CEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRM 826
CE++G WS + PTC +DCG P I+ G T + Y F Q D+ E+ V
Sbjct: 2573 CEESG-WSSSIPTCMPIDCGLPPHIDFGDCTKLKDDQGY----FEQEDDMMEVPYVTPHP 2627
Query: 827 CQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQT 886
G + KE P+ +S G Y C GY L G+
Sbjct: 2628 PYHLGAVAKTWENTKE----SPATH----------SSNFLYGTMVSYTCNPGYELLGNPV 2673
Query: 887 RTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFL 946
C G WNG+ P CI I+C P ENG + + T GS+V+Y C + G L
Sbjct: 2674 LICQEDGTWNGSAPSCISIECDLPTAPENGFLRFT--ETSMGSAVQYSCKPGHILAGSDL 2731
Query: 947 RKCLDDGRWSGEEPSCE 963
R CL++ +WSG P CE
Sbjct: 2732 RLCLENRKWSGASPRCE 2748
Score = 296 bits (727), Expect = 2e-79
Identities = 186/614 (30%), Positives = 267/614 (43%), Gaps = 36/614 (5%)
Query: 352 TCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNC 411
+C P+ ++N +I G++Y S + Y+C G++L G + R C+ D W P C V+C
Sbjct: 2751 SCKKPNPVMNGSIKGSNYTYLSTLYYECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDC 2810
Query: 412 GGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWC 471
+G V + T Y+C E F L G R C G W G P C+ C
Sbjct: 2811 SSPPVSANGQVR--GDEYTFQKEIEYTCNEGFLLEGARSRVCLANGSWSGATPDCVPVRC 2868
Query: 472 PDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGT 531
PP ++N + ++ C G+IL G+ +TC G W P CK VNCG
Sbjct: 2869 ATPPQLANGVTEGLDYGFMKEVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCKPVNCGP 2928
Query: 532 PTIHKGSFVLING-TTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPE 590
P F NG + +G Q+ C P Y L+G C +G WS PSC C
Sbjct: 2929 PEDLAHGFP--NGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCLPCRCST 2986
Query: 591 PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLP 650
P V G + D+ C G KL+G + C+ DG+WS P CE+ CG LP
Sbjct: 2987 P-VIEYGTVNGTDFDCGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHCEHTSCGSLP 3045
Query: 651 TLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPI 710
+P + ++ +VI YSC + Y + G CTE+ WS P CE + C P
Sbjct: 3046 MIPNAFIS--ETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPLSCGSP- 3102
Query: 711 VAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGES-LSTCED 769
S+ + +H TY + VK RC +GY + ++ TC+
Sbjct: 3103 ---PSVANAVATGEAH---------------TYE--SEVKLRCLEGYTMDTDTDTFTCQK 3142
Query: 770 NGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQE 829
+G+W +C C P I + + + + C E + EGV +CQ
Sbjct: 3143 DGRWFPERISCSPKKCPLPENITH--ILVHGDDFSVNRQVSVSCAEGYTFEGVNISVCQL 3200
Query: 830 NGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTC 889
+GTW EPP E P + ++ VV S + YQCE GY L+G++ R C
Sbjct: 3201 DGTW--EPPFSDESCSPVSCGKPESPEHGFVVGSKYTFESTIIYQCEPGYELEGNRERVC 3258
Query: 890 ISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKC 949
QW+G V +C C +P NGK I N +T G +V Y C Y GP C
Sbjct: 3259 QENRQWSGGVAICKETRCETPLEFLNGKADIENRTT--GPNVVYSCNRGYSLEGPSEAHC 3316
Query: 950 LDDGRWSGEEPSCE 963
++G WS P C+
Sbjct: 3317 TENGTWSHPVPLCK 3330
Score = 292 bits (717), Expect = 4e-78
Identities = 180/620 (29%), Positives = 268/620 (43%), Gaps = 50/620 (8%)
Query: 353 CGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCG 412
C P N + + +GS + Y C GH+L G R C ++ WSGA P C+ ++C
Sbjct: 2694 CDLPTAPENGFLRFTETSMGSAVQYSCKPGHILAGSDLRLCLENRKWSGASPRCEAISCK 2753
Query: 413 GLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCP 472
P+ +G + + T+ + Y C + L G RTC D+ WD + P C+ C
Sbjct: 2754 KPNPVMNGSIK--GSNYTYLSTLYYECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDCS 2811
Query: 473 DPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTP 532
PP +N V + + YTC G +L G+ S C G+WSG P C V C TP
Sbjct: 2812 SPPVSANGQVRGDEYTFQKEIEYTCNEGFLLEGARSRVCLANGSWSGATPDCVPVRCATP 2871
Query: 533 TIHKGSFVLINGTT---TYGSIAQ--FTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTS 587
L NG T YG + + F C Y L+GA +L C DG W +IP C+ +
Sbjct: 2872 P------QLANGVTEGLDYGFMKEVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCKPVN 2925
Query: 588 CPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCG 647
C PE + G+ F + I + C G+KL G + C +G WSG SP+C C
Sbjct: 2926 CGPPEDLAHGFPNGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCLPCRC- 2984
Query: 648 KLPTLPYGTMELLNGTT-HLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRC 706
P + YGT +NGT G + C ++L+G TC + QWS P CE C
Sbjct: 2985 STPVIEYGT---VNGTDFDCGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHCEHTSC 3041
Query: 707 SDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLST 766
+ + +S T + + + ++ Y C GY + G S
Sbjct: 3042 GSLPMIPNAFISETSSWKEN---------------------VITYSCRSGYVIQGSSDLI 3080
Query: 767 CEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELE-GVIRR 825
C + G WS P C+ + CG+P + N T A Y + +C E + ++
Sbjct: 3081 CTEKGVWSQPYPVCEPLSCGSPPSVANAVAT--GEAHTYESEVKLRCLEGYTMDTDTDTF 3138
Query: 826 MCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQ 885
CQ++G W E C CP P + + +LV S+ + C GY +G
Sbjct: 3139 TCQKDGRWFPERISCSPKKCPLP----ENITHILVHGDDFSVNRQVSVSCAEGYTFEGVN 3194
Query: 886 TRTCISKGQWNG--TVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVG 943
C G W + C P+ C P + E+G +V S + F S++ Y C Y+ G
Sbjct: 3195 ISVCQLDGTWEPPFSDESCSPVSCGKPESPEHGFVVGSKYT--FESTIIYQCEPGYELEG 3252
Query: 944 PFLRKCLDDGRWSGEEPSCE 963
R C ++ +WSG C+
Sbjct: 3253 NRERVCQENRQWSGGVAICK 3272
Score = 291 bits (714), Expect = 9e-78
Identities = 176/586 (30%), Positives = 255/586 (43%), Gaps = 38/586 (6%)
Query: 372 GSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRTTH 431
G+ + Y C G+ LLG+ C++DG W+G+ PSC + C T E+G + + T+
Sbjct: 2655 GTMVSYTCNPGYELLGNPVLICQEDGTWNGSAPSCISIECDLPTAPENGFLRFTE--TSM 2712
Query: 432 GARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGS 491
G+ YSC+ L G+ R C + W G +PRC C P V N S+ + + S
Sbjct: 2713 GSAVQYSCKPGHILAGSDLRLCLENRKWSGASPRCEAISCKKPNPVMNGSIKGSNYTYLS 2772
Query: 492 LASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTIHKGSFVLINGTTTYGSI 551
Y C+ G++L+G+ TC W P C V+C +P + V T+
Sbjct: 2773 TLYYECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDCSSPPVSANGQVR-GDEYTFQKE 2831
Query: 552 AQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFDYYVHSTIN 611
++TC + L GA VC +G WS P C C P + G E DY +
Sbjct: 2832 IEYTCNEGFLLEGARSRVCLANGSWSGATPDCVPVRCATPPQLANGVTEGLDYGFMKEVT 2891
Query: 612 FHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHL-GSVI 670
FHC G+ L G P L CQ DG W + P C+ ++CG L +G NG + + G I
Sbjct: 2892 FHCHEGYILHGAPKLTCQSDGNWDAEIPLCKPVNCGPPEDLAHG---FPNGFSFIHGGHI 2948
Query: 671 QYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTL 730
QY C Y+L G R C WS SSP C RCS P++ +V G D
Sbjct: 2949 QYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCLPCRCSTPVI---EYGTVNGTD------- 2998
Query: 731 IRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGR 790
D G RI +C KG+K++G S TCE +GQWS P C++ CG+
Sbjct: 2999 ------FDCGKAARI------QCFKGFKLLGLSEITCEADGQWSSGFPHCEHTSCGSLPM 3046
Query: 791 IENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSA 850
I N ++ +++ Y C + ++G +C E G WS P+C+ ++C P +
Sbjct: 3047 IPNAFIS--ETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPLSCGSPPS 3104
Query: 851 QIKAGSGLLVVTSTLSIGGEAHYQCERGYNL-KGHQTRTCISKGQWNGTVPVCIPIDCRS 909
A + + E +C GY + T TC G+W C P C
Sbjct: 3105 VANA----VATGEAHTYESEVKLRCLEGYTMDTDTDTFTCQKDGRWFPERISCSPKKCPL 3160
Query: 910 PGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRW 955
P NI + I++ V C Y G + C DG W
Sbjct: 3161 PENITH--ILVHGDDFSVNRQVSVSCAEGYTFEGVNISVCQLDGTW 3204
Score = 286 bits (701), Expect = 3e-76
Identities = 183/621 (29%), Positives = 267/621 (42%), Gaps = 43/621 (6%)
Query: 349 LPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKY 408
+P C SP N + G++Y I Y C EG +L G +SR C +G WSGA P C
Sbjct: 2806 IPVDCSSPPVSANGQVRGDEYTFQKEIEYTCNEGFLLEGARSRVCLANGSWSGATPDCVP 2865
Query: 409 VNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLF 468
V C + +G +D + C E + L G P+ TC +G WD E P C
Sbjct: 2866 VRCATPPQLANGVTEGLDYGFMK--EVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCKP 2923
Query: 469 DWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVN 528
C P +++ G Y C G+ L G++S C G+WSG PSC
Sbjct: 2924 VNCGPPEDLAHGFPNGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCLPCR 2983
Query: 529 CGTPTIHKGSFVLINGTT-TYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTS 587
C TP I G+ +NGT G A+ C + L G E+ C DG+WS P CE TS
Sbjct: 2984 CSTPVIEYGT---VNGTDFDCGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHCEHTS 3040
Query: 588 CPE-PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDC 646
C P +P+ ++ + + I + C +G+ + G +L+C + G WS P CE + C
Sbjct: 3041 CGSLPMIPN-AFISETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPLSC 3099
Query: 647 GKLPTLPYGTMELLNGTTH-LGSVIQYSCTTNYRL-VGPVRRTCTEEFQWSDSSPRCEEI 704
G P++ + G H S ++ C Y + TC ++ +W C
Sbjct: 3100 GSPPSV---ANAVATGEAHTYESEVKLRCLEGYTMDTDTDTFTCQKDGRWFPERISCSPK 3156
Query: 705 RCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESL 764
+C P ++T H L+ G+ + + V C +GY G ++
Sbjct: 3157 KCPLP-------ENIT-------HILVH-------GDDFSVNRQVSVSCAEGYTFEGVNI 3195
Query: 765 STCEDNGQWSG--TTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGV 822
S C+ +G W + +C V CG P E+G V + S TF +T YQC+ +ELEG
Sbjct: 3196 SVCQLDGTWEPPFSDESCSPVSCGKPESPEHGFV-VGSKYTF-ESTIIYQCEPGYELEGN 3253
Query: 823 IRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLK 882
R+CQEN WS ICKE C P + + + + G Y C RGY+L+
Sbjct: 3254 RERVCQENRQWSGGVAICKETRCETPLEFLNGKADI----ENRTTGPNVVYSCNRGYSLE 3309
Query: 883 GHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRV 942
G C G W+ VP+C P C P I + +S +V C +
Sbjct: 3310 GPSEAHCTENGTWSHPVPLCKPNPCPVPFVIPENAL-LSEKEFYVDQNVSIKCREGFLLQ 3368
Query: 943 GPFLRKCLDDGRWSGEEPSCE 963
G + C D W+ CE
Sbjct: 3369 GHGIITCNPDETWTQTSAKCE 3389
Score = 274 bits (671), Expect = 1e-72
Identities = 176/621 (28%), Positives = 253/621 (40%), Gaps = 46/621 (7%)
Query: 349 LPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKY 408
+P C +P +L N G DY + + C EG++L G C+ DG W P CK
Sbjct: 2864 VPVRCATPPQLANGVTEGLDYGFMKEVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCKP 2923
Query: 409 VNCGGLTPIEDGDVALIDNRT-THGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL 467
VNCG P ED + + HG Y C + L GN R C G W G +P CL
Sbjct: 2924 VNCG---PPEDLAHGFPNGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCL 2980
Query: 468 FDWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYV 527
C P + +V G A C G L G + +TC G WS P C++
Sbjct: 2981 PCRC-STPVIEYGTVNGTDFDCGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHCEHT 3039
Query: 528 NCGTPTIHKGSFVLINGTTTYG-SIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELT 586
+CG+ + +F I+ T+++ ++ ++C Y + G+ +L+C G WS P CE
Sbjct: 3040 SCGSLPMIPNAF--ISETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPL 3097
Query: 587 SCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPN-LVCQQDGEWSGDSPTCEYID 645
SC P + + S + C G+ + + + CQ+DG W + +C
Sbjct: 3098 SCGSPPSVANAVATGEAHTYESEVKLRCLEGYTMDTDTDTFTCQKDGRWFPERISCSPKK 3157
Query: 646 CGKLPTLPYGTMELLNGTTH-LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSD--SSPRCE 702
C P T L++G + + SC Y G C + W S C
Sbjct: 3158 C---PLPENITHILVHGDDFSVNRQVSVSCAEGYTFEGVNISVCQLDGTWEPPFSDESCS 3214
Query: 703 EIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGE 762
+ C P E HG VG+ Y + + Y+CE GY++ G
Sbjct: 3215 PVSCGKPESPE------------HGFV---------VGSKYTFESTIIYQCEPGYELEGN 3253
Query: 763 SLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGV 822
C++N QWSG C+ C P NGK + + T G Y C+ + LEG
Sbjct: 3254 RERVCQENRQWSGGVAICKETRCETPLEFLNGKADIENRTT--GPNVVYSCNRGYSLEGP 3311
Query: 823 IRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLK 882
C ENGTWS P+CK CP P L+ + +C G+ L+
Sbjct: 3312 SEAHCTENGTWSHPVPLCKPNPCPVP---FVIPENALLSEKEFYVDQNVSIKCREGFLLQ 3368
Query: 883 GHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRV 942
GH TC W T C I C P ++EN + +G + Y C S Y
Sbjct: 3369 GHGIITCNPDETWTQTSAKCEKISCGPPAHVENA--IARGVHYQYGDMITYSCYSGYMLE 3426
Query: 943 GPFLRK-CLDDGRWSGEEPSC 962
G FLR CL++G W+ P C
Sbjct: 3427 G-FLRSVCLENGTWT-SPPIC 3445
Score = 266 bits (653), Expect = 2e-70
Identities = 169/600 (28%), Positives = 259/600 (43%), Gaps = 40/600 (6%)
Query: 372 GSRIVYKCPEGHMLLGDKSRHCKKDGFW---SGAP-PSCKYVNCGGLTPIEDGDVALIDN 427
G Y C +G+ L + C G W G P C C + + +
Sbjct: 2017 GDIAFYYCSDGYSLADNSQLLCNAQGKWVPPEGQDMPRCIAHFCEKPPSVSYSILESVSK 2076
Query: 428 -RTTHGARALYSCRENFTLVGNPERTCGDEGIWDGE--APRCLFDWCPDPPAVSNASVTV 484
+ G+ + C E F L + + C G W+ + +C+ C +PP++ N +
Sbjct: 2077 AKFAAGSVVSFKCMEGFVLNTSAKIECMRGGQWNPSPMSIQCIPVRCGEPPSIMNGYASG 2136
Query: 485 NGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTIHKGSFVLING 544
+ + G++ +Y+C G + G TC G WS P+C V+CG P + F+
Sbjct: 2137 SNYSFGAMVAYSCNKGFYIKGEKKSTCEATGQWSSPIPTCHPVSCGEPPKVENGFLEHTT 2196
Query: 545 TTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIP-SCELTSCPEPEVPSGGYMEAFD 603
+ S ++ C P Y G+ VC + W + P C C +P G+M+ +
Sbjct: 2197 GRIFESEVRYQCNPGYKSVGSPVFVCQANRHWHSESPLMCVPLDCGKPPPIQNGFMKGEN 2256
Query: 604 YYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDS-PTCEYIDCGKLPTLPYGTMELLNG 662
+ V S + F C G++L+G+ + CQ+ G+W+ S P C C + P L + L
Sbjct: 2257 FEVGSKVQFFCNEGYELVGDSSWTCQKSGKWNKKSNPKCMPAKCPEPPLLE-NQLVLKEL 2315
Query: 663 TTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGN 722
TT +G V+ +SC + L GP C QW+DS P C+ + C+ P +
Sbjct: 2316 TTEVG-VVTFSCKEGHVLQGPSVLKCLPSQQWNDSFPVCKIVLCTPPPLI---------- 2364
Query: 723 DRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQY 782
S G + + G+ VKY C G+ + G S + C+ +G WS P C
Sbjct: 2365 --SFGVPI--------PSSALHFGSTVKYSCVGGFFLRGNSTTLCQPDGTWSSPLPECVP 2414
Query: 783 VDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKE 842
V+C P I NG + + A Y +TA Y C +EL G +C ENG W P CK
Sbjct: 2415 VECPQPEEIPNGIIDVQGLA--YLSTALYTCKPGFELVGNTTTLCGENGHWLGGKPTCKA 2472
Query: 843 ITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVC 902
I C P + +G T L G Y C RG+ L+G TC+ G W+ P C
Sbjct: 2473 IECLKPKEIL---NGKFSYTD-LHYGQTVTYSCNRGFRLEGPSALTCLETGDWDVDAPSC 2528
Query: 903 IPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
I C SP IENG + +G+ + Y C +Q G ++ C + G WS P+C
Sbjct: 2529 NAIHCDSPQPIENG--FVEGADYSYGAIIIYSCFPGFQVAGHAMQTCEESG-WSSSIPTC 2585
Score = 266 bits (651), Expect = 4e-70
Identities = 165/537 (30%), Positives = 232/537 (43%), Gaps = 42/537 (7%)
Query: 431 HGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAG 490
+G Y+C + L+GNP C ++G W+G AP C+ C P A N + G
Sbjct: 2654 YGTMVSYTCNPGYELLGNPVLICQEDGTWNGSAPSCISIECDLPTAPENGFLRFTETSMG 2713
Query: 491 SLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPT-IHKGSFVLINGTT-TY 548
S Y+C+ GHIL+GS C WSG P C+ ++C P + GS I G+ TY
Sbjct: 2714 SAVQYSCKPGHILAGSDLRLCLENRKWSGASPRCEAISCKKPNPVMNGS---IKGSNYTY 2770
Query: 549 GSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFDYYVHS 608
S + C+P Y LNG E C D W D P C C P V + G + +Y
Sbjct: 2771 LSTLYYECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDCSSPPVSANGQVRGDEYTFQK 2830
Query: 609 TINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGS 668
I + C G L G + VC +G WSG +P C + C P L G E L+
Sbjct: 2831 EIEYTCNEGFLLEGARSRVCLANGSWSGATPDCVPVRCATPPQLANGVTEGLD--YGFMK 2888
Query: 669 VIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGH 728
+ + C Y L G + TC + W P C+ + C P D +HG
Sbjct: 2889 EVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCKPVNCGPP------------EDLAHGF 2936
Query: 729 TLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNP 788
G ++ G ++Y+C GYK+ G S C NG WSG++P+C C P
Sbjct: 2937 ---------PNGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCLPCRCSTP 2987
Query: 789 GRIENGKVTLPSNATFY--GATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCP 846
IE G V N T + G A QC + ++L G+ C+ +G WS P C+ +C
Sbjct: 2988 -VIEYGTV----NGTDFDCGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHCEHTSC- 3041
Query: 847 DPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPID 906
+ + + TS+ Y C GY ++G C KG W+ PVC P+
Sbjct: 3042 --GSLPMIPNAFISETSSWK-ENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPLS 3098
Query: 907 CRSPGNIENGKIVISNGSTLFGSSVEYYCLSQY-QRVGPFLRKCLDDGRWSGEEPSC 962
C SP ++ N V + + + S V+ CL Y C DGRW E SC
Sbjct: 3099 CGSPPSVANA--VATGEAHTYESEVKLRCLEGYTMDTDTDTFTCQKDGRWFPERISC 3153
Score = 248 bits (607), Expect = 8e-65
Identities = 145/505 (28%), Positives = 219/505 (43%), Gaps = 31/505 (6%)
Query: 347 QYLPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSC 406
Q +P CG P ++N G++Y G+ + Y C +G + G+K C+ G WS P+C
Sbjct: 2117 QCIPVRCGEPPSIMNGYASGSNYSFGAMVAYSCNKGFYIKGEKKSTCEATGQWSSPIPTC 2176
Query: 407 KYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAP-R 465
V+CG +E+G + R + Y C + VG+P C W E+P
Sbjct: 2177 HPVSCGEPPKVENGFLEHTTGRIFE-SEVRYQCNPGYKSVGSPVFVCQANRHWHSESPLM 2235
Query: 466 CLFDWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVP-PSC 524
C+ C PP + N + + GS + C G+ L G +S TC G W+ P C
Sbjct: 2236 CVPLDCGKPPPIQNGFMKGENFEVGSKVQFFCNEGYELVGDSSWTCQKSGKWNKKSNPKC 2295
Query: 525 KYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCE 584
C P + + VL TT G + F+C+ + L G L C +W+ P C+
Sbjct: 2296 MPAKCPEPPLLENQLVLKELTTEVG-VVTFSCKEGHVLQGPSVLKCLPSQQWNDSFPVCK 2354
Query: 585 LTSC-PEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEY 643
+ C P P + G + + + ST+ + C G L G +CQ DG WS P C
Sbjct: 2355 IVLCTPPPLISFGVPIPSSALHFGSTVKYSCVGGFFLRGNSTTLCQPDGTWSSPLPECVP 2414
Query: 644 IDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEE 703
++C + +P G ++ + G +L + + Y+C + LVG C E W P C+
Sbjct: 2415 VECPQPEEIPNGIID-VQGLAYLSTAL-YTCKPGFELVGNTTTLCGENGHWLGGKPTCKA 2472
Query: 704 IRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGES 763
I C P S T D +G T V Y C +G+++ G S
Sbjct: 2473 IECLKPKEILNGKFSYT--DLHYGQT-------------------VTYSCNRGFRLEGPS 2511
Query: 764 LSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVI 823
TC + G W P+C + C +P IENG V + YGA Y C +++ G
Sbjct: 2512 ALTCLETGDWDVDAPSCNAIHCDSPQPIENGFVEGADYS--YGAIIIYSCFPGFQVAGHA 2569
Query: 824 RRMCQENGTWSLEPPICKEITCPDP 848
+ C+E+G WS P C I C P
Sbjct: 2570 MQTCEESG-WSSSIPTCMPIDCGLP 2593
Score = 239 bits (586), Expect = 3e-62
Identities = 168/620 (27%), Positives = 258/620 (41%), Gaps = 63/620 (10%)
Query: 352 TCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVN- 410
+CG P L N +D+ GS + Y+C G+ LLGD C +G W+G PSC V+
Sbjct: 1666 SCGVPPPLENGFHSADDFYAGSTVTYQCNNGYYLLGDSRMFCTDNGSWNGVSPSCLDVDE 1725
Query: 411 CG-GLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFD 469
C G E +D + SC +T G + C E +C
Sbjct: 1726 CAVGSDCSEHASCLNVD------GSYICSCVPPYTGDG---KNC-------AEPIKCK-- 1767
Query: 470 WCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNC 529
P P ++S + + G+ +++C+ G+ L G T +TC G W+ + P CK V+C
Sbjct: 1768 -APGNPENGHSSGEI--YTVGAEVTFSCQEGYQLMGVTKITCLESGEWNHLIPYCKAVSC 1824
Query: 530 GTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCP 589
G P I + + T+GS + C Y L G +E C + WS+ P CE C
Sbjct: 1825 GKPAIPENG-CIEELAFTFGSKVTYRCNKGYTLAGDKESSCLANSSWSHSPPVCEPVKCS 1883
Query: 590 EPE-VPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGK 648
PE + +G Y+ + Y+ ST ++ C+ G+ L G + C G W P C + CG+
Sbjct: 1884 SPENINNGKYILSGLTYL-STASYSCDTGYSLQGPSIIECTASGIWDRAPPACHLVFCGE 1942
Query: 649 LPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSD 708
P + + N T + + Y+C Y L G C + +WS S +C + C +
Sbjct: 1943 PPAIKDAVITGNNFT--FRNTVTYTCKEGYTLAGLDTIECLADGKWSRSDQQCLAVSCDE 2000
Query: 709 PIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCE 768
P + + + H L G + Y C GY + S C
Sbjct: 2001 PPIVDHA-------SPETAHRL--------------FGDIAFYYCSDGYSLADNSQLLCN 2039
Query: 769 DNGQW----SGTTPTCQYVDCGNPGRIENGKVTLPSNATF-YGATAFYQCDENWELEGVI 823
G+W P C C P + + S A F G+ ++C E + L
Sbjct: 2040 AQGKWVPPEGQDMPRCIAHFCEKPPSVSYSILESVSKAKFAAGSVVSFKCMEGFVLNTSA 2099
Query: 824 RRMCQENGTWSLEPPI--CKEITCPDPSAQIKA-GSGLLVVTSTLSIGGEAHYQCERGYN 880
+ C G W+ P C + C +P + + SG S S G Y C +G+
Sbjct: 2100 KIECMRGGQWNPSPMSIQCIPVRCGEPPSIMNGYASG-----SNYSFGAMVAYSCNKGFY 2154
Query: 881 LKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQ 940
+KG + TC + GQW+ +P C P+ C P +ENG + + G +F S V Y C Y+
Sbjct: 2155 IKGEKKSTCEATGQWSSPIPTCHPVSCGEPPKVENGFLEHTTG-RIFESEVRYQCNPGYK 2213
Query: 941 RVGPFLRKCLDDGRWSGEEP 960
VG + C + W E P
Sbjct: 2214 SVGSPVFVCQANRHWHSESP 2233
Score = 234 bits (572), Expect = 1e-60
Identities = 159/605 (26%), Positives = 252/605 (41%), Gaps = 62/605 (10%)
Query: 368 DYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDN 427
D GS++ C G L+G+ ++C G W+ P C+ ++CG P+E+G + D
Sbjct: 1624 DLKPGSKVNLFCDPGFQLVGNPVQYCLNQGQWTQPLPHCERISCGVPPPLENGFHSADDF 1683
Query: 428 RTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL-FDWCPDPPAVSNASVTVNG 486
G+ Y C + L+G+ C D G W+G +P CL D C
Sbjct: 1684 YA--GSTVTYQCNNGYYLLGDSRMFCTDNGSWNGVSPSCLDVDEC--------------- 1726
Query: 487 HKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSC-KYVNCGTPTIHKGSFVLINGT 545
++ S E+ L+ S C+ ++G +C + + C P +
Sbjct: 1727 ----AVGSDCSEHASCLNVDGSYICSCVPPYTGDGKNCAEPIKCKAPGNPENGH-SSGEI 1781
Query: 546 TTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFDYY 605
T G+ F+C+ Y L G ++ C G+W++ IP C+ SC +P +P G +E +
Sbjct: 1782 YTVGAEVTFSCQEGYQLMGVTKITCLESGEWNHLIPYCKAVSCGKPAIPENGCIEELAFT 1841
Query: 606 VHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTH 665
S + + C G+ L G+ C + WS P CE + C + G +L+G T+
Sbjct: 1842 FGSKVTYRCNKGYTLAGDKESSCLANSSWSHSPPVCEPVKCSSPENINNGKY-ILSGLTY 1900
Query: 666 LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRS 725
L S YSC T Y L GP CT W + P C + C +P + ++++
Sbjct: 1901 L-STASYSCDTGYSLQGPSIIECTASGIWDRAPPACHLVFCGEPPAIKDAVIT------- 1952
Query: 726 HGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDC 785
GN + V Y C++GY + G C +G+WS + C V C
Sbjct: 1953 --------------GNNFTFRNTVTYTCKEGYTLAGLDTIECLADGKWSRSDQQCLAVSC 1998
Query: 786 GNPGRIENGKVTLPSNA-TFYGATAFYQCDENWELEGVIRRMCQENGTW----SLEPPIC 840
P +++ P A +G AFY C + + L + +C G W + P C
Sbjct: 1999 DEPPIVDHAS---PETAHRLFGDIAFYYCSDGYSLADNSQLLCNAQGKWVPPEGQDMPRC 2055
Query: 841 KEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVP 900
C P + + V + + G ++C G+ L C+ GQWN + P
Sbjct: 2056 IAHFCEKPPS-VSYSILESVSKAKFAAGSVVSFKCMEGFVLNTSAKIECMRGGQWNPS-P 2113
Query: 901 V---CIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSG 957
+ CIP+ C P +I NG SN S FG+ V Y C + G C G+WS
Sbjct: 2114 MSIQCIPVRCGEPPSIMNGYASGSNYS--FGAMVAYSCNKGFYIKGEKKSTCEATGQWSS 2171
Query: 958 EEPSC 962
P+C
Sbjct: 2172 PIPTC 2176
Score = 165 bits (402), Expect = 6e-40
Identities = 124/483 (25%), Positives = 191/483 (39%), Gaps = 49/483 (10%)
Query: 352 TCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNC 411
+CGS + N I + I Y C G+++ G C + G WS P C+ ++C
Sbjct: 3040 SCGSLPMIPNAFISETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPLSC 3099
Query: 412 GGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPER-TCGDEGIWDGEAPRCLFDW 470
G +P + T+ + C E +T+ + + TC +G W E C
Sbjct: 3100 G--SPPSVANAVATGEAHTYESEVKLRCLEGYTMDTDTDTFTCQKDGRWFPERISCSPKK 3157
Query: 471 CPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPP----SCKY 526
CP P +++ V + S +C G+ G C L G W PP SC
Sbjct: 3158 CPLPENITHILVHGDDFSVNRQVSVSCAEGYTFEGVNISVCQLDGTWE--PPFSDESCSP 3215
Query: 527 VNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELT 586
V+CG P + FV + T+ S + CEP Y L G E VC + +WS + C+ T
Sbjct: 3216 VSCGKPESPEHGFV-VGSKYTFESTIIYQCEPGYELEGNRERVCQENRQWSGGVAICKET 3274
Query: 587 SCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDC 646
C P G + + + + C G+ L G C ++G WS P C+ C
Sbjct: 3275 RCETPLEFLNGKADIENRTTGPNVVYSCNRGYSLEGPSEAHCTENGTWSHPVPLCKPNPC 3334
Query: 647 GKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRC 706
+P + L ++ + C + L G TC + W+ +S +CE+I C
Sbjct: 3335 PVPFVIPENAL-LSEKEFYVDQNVSIKCREGFLLQGHGIITCNPDETWTQTSAKCEKISC 3393
Query: 707 SDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLST 766
P E +I G Y+ G ++ Y C GY + G S
Sbjct: 3394 GPPAHVENAIAR---------------------GVHYQYGDMITYSCYSGYMLEGFLRSV 3432
Query: 767 CEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRM 826
C +NG W+ + P C+ V C P +NG + NA C E W + R+
Sbjct: 3433 CLENGTWT-SPPICRAV-CRFP--CQNGGICQRPNAC--------SCPEGW-----MGRL 3475
Query: 827 CQE 829
C+E
Sbjct: 3476 CEE 3478
Score = 153 bits (371), Expect = 3e-36
Identities = 103/369 (27%), Positives = 145/369 (39%), Gaps = 13/369 (3%)
Query: 345 ICQYLPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRH-CKKDGFWSGAP 403
+C+ P +CGSP + N G + S + +C EG+ + D C+KDG W
Sbjct: 3093 VCE--PLSCGSPPSVANAVATGEAHTYESEVKLRCLEGYTMDTDTDTFTCQKDGRWFPER 3150
Query: 404 PSCKYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDG-- 461
SC C P + + + + + SC E +T G C +G W+
Sbjct: 3151 ISCSPKKCP--LPENITHILVHGDDFSVNRQVSVSCAEGYTFEGVNISVCQLDGTWEPPF 3208
Query: 462 EAPRCLFDWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVP 521
C C P + + V + + S Y CE G+ L G+ C WSG
Sbjct: 3209 SDESCSPVSCGKPESPEHGFVVGSKYTFESTIIYQCEPGYELEGNRERVCQENRQWSGGV 3268
Query: 522 PSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIP 581
CK C TP I TT G ++C Y L G E C +G WS+ +P
Sbjct: 3269 AICKETRCETPLEFLNGKADIENRTT-GPNVVYSCNRGYSLEGPSEAHCTENGTWSHPVP 3327
Query: 582 SCELTSCPEPEV-PSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPT 640
C+ CP P V P + ++YV ++ C G L G + C D W+ S
Sbjct: 3328 LCKPNPCPVPFVIPENALLSEKEFYVDQNVSIKCREGFLLQGHGIITCNPDETWTQTSAK 3387
Query: 641 CEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPR 700
CE I CG P G +I YSC + Y L G +R C E W+ S P
Sbjct: 3388 CEKISCG--PPAHVENAIARGVHYQYGDMITYSCYSGYMLEGFLRSVCLENGTWT-SPPI 3444
Query: 701 CEEIRCSDP 709
C + C P
Sbjct: 3445 CRAV-CRFP 3452
Score = 128 bits (309), Expect = 1e-28
Identities = 100/347 (28%), Positives = 146/347 (42%), Gaps = 38/347 (10%)
Query: 644 IDCGKLPTLPYGTMELLNGTTHL--GSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRC 701
I C P L L + L GS + C ++LVG + C + QW+ P C
Sbjct: 1603 IFCSDCPRLGGSVPHLRTASEDLKPGSKVNLFCDPGFQLVGNPVQYCLNQGQWTQPLPHC 1662
Query: 702 EEIRCSDPIVAEKSIVSV----TGNDRSH----GHTLIRTSDN--RDVG--NTYRIGALV 749
E I C P E S G+ ++ G+ L+ S D G N L
Sbjct: 1663 ERISCGVPPPLENGFHSADDFYAGSTVTYQCNNGYYLLGDSRMFCTDNGSWNGVSPSCLD 1722
Query: 750 KYRCEKG---------YKVIGESLSTCEDNGQWSGTTPTC-QYVDCGNPGRIENGKVTLP 799
C G V G + +C ++G C + + C PG ENG
Sbjct: 1723 VDECAVGSDCSEHASCLNVDGSYICSCVP--PYTGDGKNCAEPIKCKAPGNPENGH---- 1776
Query: 800 SNATFY--GATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSG 857
S+ Y GA + C E ++L GV + C E+G W+ P CK ++C P+
Sbjct: 1777 SSGEIYTVGAEVTFSCQEGYQLMGVTKITCLESGEWNHLIPYCKAVSCGKPAIPENGCIE 1836
Query: 858 LLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGK 917
L T G + Y+C +GY L G + +C++ W+ + PVC P+ C SP NI NGK
Sbjct: 1837 ELAFT----FGSKVTYRCNKGYTLAGDKESSCLANSSWSHSPPVCEPVKCSSPENINNGK 1892
Query: 918 IVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCEL 964
++S G T + S+ Y C + Y GP + +C G W P+C L
Sbjct: 1893 YILS-GLT-YLSTASYSCDTGYSLQGPSIIECTASGIWDRAPPACHL 1937
Score = 77.4 bits (182), Expect = 3e-13
Identities = 44/163 (26%), Positives = 68/163 (41%), Gaps = 6/163 (3%)
Query: 752 RCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFY 811
RC G+ ++G S+ C NG WSG+ C+ C + + ++G ++ + Y T
Sbjct: 382 RCHPGFDLVGSSIILCLPNGLWSGSESYCRVRTCPHLRQPKHGHISCSTREMLYKTTCLV 441
Query: 812 QCDENWELEGVIRRMCQENGTWSLEPPICKEITCPD---PSAQIKAGSGLLVVTSTLSIG 868
CDE + LEG + CQ N W P C E C P I + G
Sbjct: 442 ACDEGYRLEGSDKLTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISPHN--CGKQPAKFG 499
Query: 869 GEAHYQCERGYNLKG-HQTRTCISKGQWNGTVPVCIPIDCRSP 910
+ C +G+ L G + C + G+WN V + D +P
Sbjct: 500 TICYVSCRQGFILSGVKEMLRCTTSGKWNVGVQAAVCKDVEAP 542
Score = 76.6 bits (180), Expect = 5e-13
Identities = 47/196 (23%), Positives = 76/196 (38%), Gaps = 7/196 (3%)
Query: 405 SCKYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAP 464
+C+ V+C L P E+G A C F LVG+ C G+W G
Sbjct: 349 TCELVHCPALKPPENGYFIQNTCNNHFNAACGVRCHPGFDLVGSSIILCLPNGLWSGSES 408
Query: 465 RCLFDWCPD--PPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPP 522
C CP P + S + + C+ G+ L GS +TC W G P
Sbjct: 409 YCRVRTCPHLRQPKHGHISCSTREMLYKTTCLVACDEGYRLEGSDKLTCQGNSQWDGPEP 468
Query: 523 SCKYVNCGTPTIHKGSFVLING----TTTYGSIAQFTCEPDYWLNGAEELV-CNRDGKWS 577
C +C T + K + + +G+I +C + L+G +E++ C GKW+
Sbjct: 469 RCVERHCSTFQMPKDVIISPHNCGKQPAKFGTICYVSCRQGFILSGVKEMLRCTTSGKWN 528
Query: 578 YDIPSCELTSCPEPEV 593
+ + P++
Sbjct: 529 VGVQAAVCKDVEAPQI 544
Score = 74.1 bits (174), Expect = 2e-12
Identities = 46/158 (29%), Positives = 68/158 (43%), Gaps = 8/158 (5%)
Query: 378 KCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRTTHGARALY 437
+C G L+G C +G WSG+ C+ C L + G ++ + L
Sbjct: 382 RCHPGFDLVGSSIILCLPNGLWSGSESYCRVRTCPHLRQPKHGHISCSTREMLYKTTCLV 441
Query: 438 SCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWC-----PDPPAVSNASVTVNGHKAGSL 492
+C E + L G+ + TC WDG PRC+ C P +S + K G++
Sbjct: 442 ACDEGYRLEGSDKLTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISPHNCGKQPAKFGTI 501
Query: 493 ASYTCENGHILSG-STSVTCTLGGAWS-GVPPS-CKYV 527
+C G ILSG + CT G W+ GV + CK V
Sbjct: 502 CYVSCRQGFILSGVKEMLRCTTSGKWNVGVQAAVCKDV 539
Score = 72.5 bits (170), Expect = 7e-12
Identities = 43/155 (27%), Positives = 64/155 (41%), Gaps = 4/155 (2%)
Query: 566 EELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYM--EAFDYYVHSTINFHCEAGHKLIGE 623
E+ VC R+G + +CEL CP + P GY + + ++ C G L+G
Sbjct: 335 EDCVC-REG-YRASGQTCELVHCPALKPPENGYFIQNTCNNHFNAACGVRCHPGFDLVGS 392
Query: 624 PNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGP 683
++C +G WSG C C L +G + + +C YRL G
Sbjct: 393 SIILCLPNGLWSGSESYCRVRTCPHLRQPKHGHISCSTREMLYKTTCLVACDEGYRLEGS 452
Query: 684 VRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVS 718
+ TC QW PRC E CS + + I+S
Sbjct: 453 DKLTCQGNSQWDGPEPRCVERHCSTFQMPKDVIIS 487
Score = 72.1 bits (169), Expect = 1e-11
Identities = 39/122 (31%), Positives = 57/122 (46%), Gaps = 2/122 (1%)
Query: 841 KEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVP 900
K I C D + L + L G + + C+ G+ L G+ + C+++GQW +P
Sbjct: 1601 KSIFCSDCPRLGGSVPHLRTASEDLKPGSKVNLFCDPGFQLVGNPVQYCLNQGQWTQPLP 1660
Query: 901 VCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEP 960
C I C P +ENG S GS+V Y C + Y +G C D+G W+G P
Sbjct: 1661 HCERISCGVPPPLENG--FHSADDFYAGSTVTYQCNNGYYLLGDSRMFCTDNGSWNGVSP 1718
Query: 961 SC 962
SC
Sbjct: 1719 SC 1720
Score = 63.7 bits (148), Expect = 3e-09
Identities = 47/206 (22%), Positives = 78/206 (37%), Gaps = 8/206 (3%)
Query: 498 ENGHILSGSTSVT-CTLGGAWSGVPPSCKYVNC-GTPTIHKGSFVLINGTTTYGSIAQFT 555
EN GSTS C + +C+ V+C G F+ + +
Sbjct: 323 ENHTSPPGSTSPEDCVCREGYRASGQTCELVHCPALKPPENGYFIQNTCNNHFNAACGVR 382
Query: 556 CEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAF--DYYVHSTINFH 613
C P + L G+ ++C +G WS C + +CP P G++ + +T
Sbjct: 383 CHPGFDLVGSSIILCLPNGLWSGSESYCRVRTCPHLRQPKHGHISCSTREMLYKTTCLVA 442
Query: 614 CEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCG--KLP-TLPYGTMELLNGTTHLGSVI 670
C+ G++L G L CQ + +W G P C C ++P + G++
Sbjct: 443 CDEGYRLEGSDKLTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISPHNCGKQPAKFGTIC 502
Query: 671 QYSCTTNYRLVGPVRR-TCTEEFQWS 695
SC + L G CT +W+
Sbjct: 503 YVSCRQGFILSGVKEMLRCTTSGKWN 528
Score = 60.9 bits (141), Expect = 2e-08
Identities = 48/194 (24%), Positives = 73/194 (37%), Gaps = 8/194 (4%)
Query: 767 CEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRM 826
C + + SG T C+ V C ENG + + A +C ++L G +
Sbjct: 339 CREGYRASGQT--CELVHCPALKPPENGYFIQNTCNNHFNAACGVRCHPGFDLVGSSIIL 396
Query: 827 CQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQT 886
C NG WS C+ TCP Q K G + T + C+ GY L+G
Sbjct: 397 CLPNGLWSGSESYCRVRTCPH-LRQPKHGH-ISCSTREMLYKTTCLVACDEGYRLEGSDK 454
Query: 887 RTCISKGQWNGTVPVCIPIDC---RSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVG 943
TC QW+G P C+ C + P ++ FG+ C + G
Sbjct: 455 LTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISPHNCGKQPAKFGTICYVSCRQGFILSG 514
Query: 944 -PFLRKCLDDGRWS 956
+ +C G+W+
Sbjct: 515 VKEMLRCTTSGKWN 528
Score = 46.0 bits (104), Expect = 7e-04
Identities = 23/89 (25%), Positives = 37/89 (41%)
Query: 874 QCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEY 933
+C G++L G C+ G W+G+ C C ++G I S L+ ++
Sbjct: 382 RCHPGFDLVGSSIILCLPNGLWSGSESYCRVRTCPHLRQPKHGHISCSTREMLYKTTCLV 441
Query: 934 YCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
C Y+ G C + +W G EP C
Sbjct: 442 ACDEGYRLEGSDKLTCQGNSQWDGPEPRC 470
Score = 46.0 bits (104), Expect = 7e-04
Identities = 19/57 (33%), Positives = 27/57 (47%), Gaps = 3/57 (5%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
CG PA+P N + E G+ Y C++GY L G ++ C W+ PP C
Sbjct: 1824 CGKPAIPENGCIE---ELAFTFGSKVTYRCNKGYTLAGDKESSCLANSSWSHSPPVC 1877
Score = 42.3 bits (95), Expect = 0.009
Identities = 22/61 (36%), Positives = 26/61 (42%), Gaps = 3/61 (4%)
Query: 1 RCGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGT 60
RC P N + I EN G VY C+ GY L G + CT G W+ P C
Sbjct: 3275 RCETPLEFLNGKADI---ENRTTGPNVVYSCNRGYSLEGPSEAHCTENGTWSHPVPLCKP 3331
Query: 61 N 61
N
Sbjct: 3332 N 3332
Score = 40.3 bits (90), Expect = 0.037
Identities = 17/52 (32%), Positives = 24/52 (46%)
Query: 7 VPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
VPP + ++ AG+ Y+C+ GY L G + CT G W P C
Sbjct: 1669 VPPPLENGFHSADDFYAGSTVTYQCNNGYYLLGDSRMFCTDNGSWNGVSPSC 1720
Score = 40.3 bits (90), Expect = 0.037
Identities = 23/67 (34%), Positives = 30/67 (44%), Gaps = 4/67 (5%)
Query: 14 SIPNEENIVAG----TIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTNVAFRKPAN 69
+I N + I++G + A Y CD GY L G ECT G W PP C PA
Sbjct: 1887 NINNGKYILSGLTYLSTASYSCDTGYSLQGPSIIECTASGIWDRAPPACHLVFCGEPPAI 1946
Query: 70 QSTTVRG 76
+ + G
Sbjct: 1947 KDAVITG 1953
Score = 39.1 bits (87), Expect = 0.085
Identities = 22/68 (32%), Positives = 29/68 (42%), Gaps = 4/68 (5%)
Query: 1 RCGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGT 60
+C P P N S E G + C EGY+L G + C G+W P+C
Sbjct: 1765 KCKAPGNPENGHSS---GEIYTVGAEVTFSCQEGYQLMGVTKITCLESGEWNHLIPYCKA 1821
Query: 61 NVAFRKPA 68
V+ KPA
Sbjct: 1822 -VSCGKPA 1828
Score = 38.7 bits (86), Expect = 0.11
Identities = 19/78 (24%), Positives = 34/78 (43%)
Query: 889 CISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRK 948
C+ + + + C + C + ENG + + + F ++ C + VG +
Sbjct: 337 CVCREGYRASGQTCELVHCPALKPPENGYFIQNTCNNHFNAACGVRCHPGFDLVGSSIIL 396
Query: 949 CLDDGRWSGEEPSCELAT 966
CL +G WSG E C + T
Sbjct: 397 CLPNGLWSGSESYCRVRT 414
Score = 37.5 bits (83), Expect = 0.26
Identities = 23/77 (29%), Positives = 29/77 (37%), Gaps = 7/77 (9%)
Query: 8 PPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTNVAFRKP 67
P + PN + + G Y+C GY+L G R C G W+ P C P
Sbjct: 2929 PEDLAHGFPNGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSC-------LP 2981
Query: 68 ANQSTTVRGGAAANGND 84
ST V NG D
Sbjct: 2982 CRCSTPVIEYGTVNGTD 2998
Score = 37.1 bits (82), Expect = 0.34
Identities = 16/58 (27%), Positives = 26/58 (44%), Gaps = 3/58 (5%)
Query: 1 RCGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
RCG P P+ + N G + Y C++G+ + G ++ C G W+ P C
Sbjct: 2122 RCGEP---PSIMNGYASGSNYSFGAMVAYSCNKGFYIKGEKKSTCEATGQWSSPIPTC 2176
Score = 37.1 bits (82), Expect = 0.34
Identities = 21/57 (36%), Positives = 26/57 (45%), Gaps = 3/57 (5%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C P V N +V +E I Y C+EG+ L GAR R C G W+ P C
Sbjct: 2810 CSSPPVSANGQVR--GDEYTFQKEIE-YTCNEGFLLEGARSRVCLANGSWSGATPDC 2863
Score = 35.9 bits (79), Expect = 0.79
Identities = 17/48 (35%), Positives = 22/48 (45%)
Query: 29 YECDEGYELFGARQRECTLRGDWTLEPPFCGTNVAFRKPANQSTTVRG 76
YECD GY L G +R C +W + P C P + + VRG
Sbjct: 2776 YECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDCSSPPVSANGQVRG 2823
Score = 34.7 bits (76), Expect = 1.8
Identities = 15/42 (35%), Positives = 19/42 (45%)
Query: 17 NEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
+ N + GT+ Y C+ GYEL G C G W P C
Sbjct: 2648 HSSNFLYGTMVSYTCNPGYELLGNPVLICQEDGTWNGSAPSC 2689
Score = 34.7 bits (76), Expect = 1.8
Identities = 21/57 (36%), Positives = 24/57 (42%), Gaps = 4/57 (7%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
CG PA NA I + G + Y C GY L G + C G WT PP C
Sbjct: 3393 CGPPAHVENA---IARGVHYQYGDMITYSCYSGYMLEGFLRSVCLENGTWT-SPPIC 3445
Score = 34.3 bits (75), Expect = 2.4
Identities = 18/57 (31%), Positives = 23/57 (40%), Gaps = 1/57 (1%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C H P + +S E + T V CDEGY L G+ + C W P C
Sbjct: 415 CPHLRQPKHGHISCSTREMLYKTTCLV-ACDEGYRLEGSDKLTCQGNSQWDGPEPRC 470
Score = 34.3 bits (75), Expect = 2.4
Identities = 18/57 (31%), Positives = 26/57 (45%), Gaps = 3/57 (5%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
CG + PNA +S E + + Y C GY + G+ CT +G W+ P C
Sbjct: 3041 CGSLPMIPNAFIS---ETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVC 3094
Score = 34.3 bits (75), Expect = 2.4
Identities = 18/51 (35%), Positives = 25/51 (49%), Gaps = 3/51 (5%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWT 52
CG P P + V + TI +Y+C+ GYEL G R+R C W+
Sbjct: 3218 CGKPESPEHGFVV--GSKYTFESTI-IYQCEPGYELEGNRERVCQENRQWS 3265
Score = 33.5 bits (73), Expect = 4.2
Identities = 12/35 (34%), Positives = 16/35 (45%)
Query: 24 GTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
G Y C+ G+ L G C GDW ++ P C
Sbjct: 2494 GQTVTYSCNRGFRLEGPSALTCLETGDWDVDAPSC 2528
Score = 33.5 bits (73), Expect = 4.2
Identities = 13/30 (43%), Positives = 16/30 (53%)
Query: 29 YECDEGYELFGARQRECTLRGDWTLEPPFC 58
+ C EGY L GA + C G+W E P C
Sbjct: 2892 FHCHEGYILHGAPKLTCQSDGNWDAEIPLC 2921
Score = 33.1 bits (72), Expect = 5.6
Identities = 17/49 (34%), Positives = 22/49 (44%), Gaps = 2/49 (4%)
Query: 8 PPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPP 56
PP + P + + G IA Y C +GY L Q C +G W PP
Sbjct: 2001 PPIVDHASPETAHRLFGDIAFYYCSDGYSLADNSQLLCNAQGKWV--PP 2047
Score = 33.1 bits (72), Expect = 5.6
Identities = 15/44 (34%), Positives = 19/44 (43%)
Query: 8 PPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDW 51
PP + EN G+ + C+EGYEL G C G W
Sbjct: 2244 PPPIQNGFMKGENFEVGSKVQFFCNEGYELVGDSSWTCQKSGKW 2287
Score = 32.7 bits (71), Expect = 7.4
Identities = 15/51 (29%), Positives = 19/51 (37%)
Query: 8 PPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
PP + ++ N Y C EGY L G EC G W+ C
Sbjct: 1943 PPAIKDAVITGNNFTFRNTVTYTCKEGYTLAGLDTIECLADGKWSRSDQQC 1993
>AJ619977-1|CAF04067.1| 3574|Homo sapiens SEL-OB protein protein.
Length = 3574
Score = 313 bits (769), Expect = 2e-84
Identities = 187/624 (29%), Positives = 280/624 (44%), Gaps = 40/624 (6%)
Query: 350 PPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYV 409
P C +P N G Y VG+ + + C EG+ L+G C + G W+ P CK V
Sbjct: 1789 PIKCKAPGNPENGHSSGEIYTVGAEVTFSCQEGYQLMGVTKITCLESGEWNHLIPYCKAV 1848
Query: 410 NCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFD 469
+CG E+G + + T G++ Y C + +TL G+ E +C W P C
Sbjct: 1849 SCGKPAIPENGCIEEL--AFTFGSKVTYRCNKGYTLAGDKESSCLANSSWSHSPPVCEPV 1906
Query: 470 WCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNC 529
C P ++N ++G S ASY+C+ G+ L G + + CT G W PP+C V C
Sbjct: 1907 KCSSPENINNGKYILSGLTYLSTASYSCDTGYSLQGPSIIECTASGIWDRAPPACHLVFC 1966
Query: 530 GTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCP 589
G P K + V+ T+ + +TC+ Y L G + + C DGKWS C SC
Sbjct: 1967 GEPPAIKDA-VITGNNFTFRNTVTYTCKEGYTLAGLDTIECLADGKWSRSDQQCLAVSCD 2025
Query: 590 EPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEW----SGDSPTCEYID 645
EP + E ++C G+ L L+C G+W D P C
Sbjct: 2026 EPPIVDHASPETAHRLFGDIAFYYCSDGYSLADNSQLLCNAQGKWVPPEGQDMPRCIAHF 2085
Query: 646 CGKLPTLPYGTMELLNGTTH-LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDS--SPRCE 702
C K P++ Y +E ++ GSV+ + C + L + C QW+ S S +C
Sbjct: 2086 CEKPPSVSYSILESVSKAKFAAGSVVSFKCMEGFVLNTSAKIECMRGGQWNPSPMSIQCI 2145
Query: 703 EIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGE 762
+RC +P SI+ +G+ G+ Y GA+V Y C KG+ + GE
Sbjct: 2146 PVRCGEP----PSIM--------NGYA---------SGSNYSFGAMVAYSCNKGFYIKGE 2184
Query: 763 SLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGV 822
STCE GQWS PTC V CG P ++ENG + + F YQC+ ++ G
Sbjct: 2185 KKSTCEATGQWSSPIPTCHPVSCGEPPKVENGFLEHTTGRIFESEVR-YQCNPGYKSVGS 2243
Query: 823 IRRMCQENGTWSLEPPI-CKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNL 881
+CQ N W E P+ C + C P I+ G + +G + + C GY L
Sbjct: 2244 PVFVCQANRHWHSESPLMCVPLDCGKP-PPIQNG---FMKGENFEVGSKVQFFCNEGYEL 2299
Query: 882 KGHQTRTCISKGQWN-GTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQ 940
G + TC G+WN + P C+P C P +EN ++V+ +T G V + C +
Sbjct: 2300 VGDSSWTCQKSGKWNKKSNPKCMPAKCPEPPLLEN-QLVLKELTTEVG-VVTFSCKEGHV 2357
Query: 941 RVGPFLRKCLDDGRWSGEEPSCEL 964
GP + KCL +W+ P C++
Sbjct: 2358 LQGPSVLKCLPSQQWNDSFPVCKI 2381
Score = 312 bits (766), Expect = 5e-84
Identities = 187/641 (29%), Positives = 283/641 (44%), Gaps = 41/641 (6%)
Query: 349 LPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSG-APPSCK 407
+P CG P + N + G +++VGS++ + C EG+ L+GD S C+K G W+ + P C
Sbjct: 2263 VPLDCGKPPPIQNGFMKGENFEVGSKVQFFCNEGYELVGDSSWTCQKSGKWNKKSNPKCM 2322
Query: 408 YVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL 467
C P+ + + L + T G +SC+E L G C W+ P C
Sbjct: 2323 PAKCPE-PPLLENQLVLKELTTEVGV-VTFSCKEGHVLQGPSVLKCLPSQQWNDSFPVCK 2380
Query: 468 FDWCPDPPAVS-NASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKY 526
C PP +S + + GS Y+C G L G+++ C G WS P C
Sbjct: 2381 IVLCTPPPLISFGVPIPSSALHFGSTVKYSCVGGFFLRGNSTTLCQPDGTWSSPLPECVP 2440
Query: 527 VNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELT 586
V C P + + G Y S A +TC+P + L G +C +G W P+C+
Sbjct: 2441 VECPQPEEIPNGIIDVQGLA-YLSTALYTCKPGFELVGNTTTLCGENGHWLGGKPTCKAI 2499
Query: 587 SCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDC 646
C +P+ G D + T+ + C G +L G L C + G+W D+P+C I C
Sbjct: 2500 ECLKPKEILNGKFSYTDLHYGQTVTYSCNRGFRLEGPSALTCLETGDWDVDAPSCNAIHC 2559
Query: 647 GKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRC 706
+ G +E G++I YSC +++ G +TC EE WS S P C I C
Sbjct: 2560 DSPQPIENGFVE--GADYSYGAIIIYSCFPGFQVAGHAMQTC-EESGWSSSIPTCMPIDC 2616
Query: 707 SDP-----------------IVAEKSIVSV---TGNDRSHGHTLIRTSDNRDVG-----N 741
P E ++ V T + H + +T +N +
Sbjct: 2617 GLPPHIDFGDCTKLKDDQGYFEQEDDMMEVPYVTPHPPYHLGAVAKTWENTKESPATHSS 2676
Query: 742 TYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSN 801
+ G +V Y C GY+++G + C+++G W+G+ P+C ++C P ENG L
Sbjct: 2677 NFLYGTMVSYTCNPGYELLGNPVLICQEDGTWNGSAPSCISIECDLPTAPENG--FLRFT 2734
Query: 802 ATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVV 861
T G+ Y C L G R+C EN WS P C+ I+C P+ + GS +
Sbjct: 2735 ETSMGSAVQYSCKPGHILAGSDLRLCLENRKWSGASPRCEAISCKKPN-PVMNGS---IK 2790
Query: 862 TSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVIS 921
S + +Y+C+ GY L G + RTC W+ P+CIP+DC SP NG+ +
Sbjct: 2791 GSNYTYLSTLYYECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDCSSPPVSANGQ--VR 2848
Query: 922 NGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
F +EY C + G R CL +G WSG P C
Sbjct: 2849 GDEYTFQKEIEYTCNEGFLLEGARSRVCLANGSWSGATPDC 2889
Score = 297 bits (729), Expect = 1e-79
Identities = 180/617 (29%), Positives = 273/617 (44%), Gaps = 49/617 (7%)
Query: 350 PPTCGSPDKLLNTTILGNDYDV-GSRIVYKCPEGHMLLGDKSRHCKKDGFW-SGAPPSCK 407
P +CG P K+ N + + S + Y+C G+ +G C+ + W S +P C
Sbjct: 2204 PVSCGEPPKVENGFLEHTTGRIFESEVRYQCNPGYKSVGSPVFVCQANRHWHSESPLMCV 2263
Query: 408 YVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEA-PRC 466
++CG PI++G + G++ + C E + LVG+ TC G W+ ++ P+C
Sbjct: 2264 PLDCGKPPPIQNGFMK--GENFEVGSKVQFFCNEGYELVGDSSWTCQKSGKWNKKSNPKC 2321
Query: 467 LFDWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKY 526
+ CP+PP + N V + +++C+ GH+L G + + C W+ P CK
Sbjct: 2322 MPAKCPEPPLLENQLVLKELTTEVGVVTFSCKEGHVLQGPSVLKCLPSQQWNDSFPVCKI 2381
Query: 527 VNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELT 586
V C P + + + +GS +++C ++L G +C DG WS +P C
Sbjct: 2382 VLCTPPPLISFGVPIPSSALHFGSTVKYSCVGGFFLRGNSTTLCQPDGTWSSPLPECVPV 2441
Query: 587 SCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDC 646
CP+PE G ++ ST + C+ G +L+G +C ++G W G PTC+ I+C
Sbjct: 2442 ECPQPEEIPNGIIDVQGLAYLSTALYTCKPGFELVGNTTTLCGENGHWLGGKPTCKAIEC 2501
Query: 647 GKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRC 706
K + G + H G + YSC +RL GP TC E W +P C I C
Sbjct: 2502 LKPKEILNGKFSYTD--LHYGQTVTYSCNRGFRLEGPSALTCLETGDWDVDAPSCNAIHC 2559
Query: 707 SDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLST 766
P E V G Y GA++ Y C G++V G ++ T
Sbjct: 2560 DSPQPIENGFVE---------------------GADYSYGAIIIYSCFPGFQVAGHAMQT 2598
Query: 767 CEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRM 826
CE++G WS + PTC +DCG P I+ G T + Y F Q D+ E+ V
Sbjct: 2599 CEESG-WSSSIPTCMPIDCGLPPHIDFGDCTKLKDDQGY----FEQEDDMMEVPYVTPHP 2653
Query: 827 CQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQT 886
G + KE P+ +S G Y C GY L G+
Sbjct: 2654 PYHLGAVAKTWENTKE----SPATH----------SSNFLYGTMVSYTCNPGYELLGNPV 2699
Query: 887 RTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFL 946
C G WNG+ P CI I+C P ENG + + T GS+V+Y C + G L
Sbjct: 2700 LICQEDGTWNGSAPSCISIECDLPTAPENGFLRFT--ETSMGSAVQYSCKPGHILAGSDL 2757
Query: 947 RKCLDDGRWSGEEPSCE 963
R CL++ +WSG P CE
Sbjct: 2758 RLCLENRKWSGASPRCE 2774
Score = 293 bits (719), Expect = 2e-78
Identities = 185/614 (30%), Positives = 266/614 (43%), Gaps = 36/614 (5%)
Query: 352 TCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNC 411
+C P+ ++N +I G++Y S + Y+C G++L G + R C+ D W P C V+C
Sbjct: 2777 SCKKPNPVMNGSIKGSNYTYLSTLYYECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDC 2836
Query: 412 GGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWC 471
+G V + T Y+C E F L G R C G W G P C+ C
Sbjct: 2837 SSPPVSANGQVR--GDEYTFQKEIEYTCNEGFLLEGARSRVCLANGSWSGATPDCVPVRC 2894
Query: 472 PDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGT 531
PP ++N + ++ C G+IL G+ +TC G W P CK VNCG
Sbjct: 2895 ATPPQLANGVTEGLDYGFMKEVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCKPVNCGP 2954
Query: 532 PTIHKGSFVLING-TTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPE 590
P F NG + +G Q+ C P Y L+G C +G WS PSC C
Sbjct: 2955 PEDLAHGFP--NGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCLPCRCST 3012
Query: 591 PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLP 650
P V G + D+ C G KL+G + C+ DG+WS P CE+ CG LP
Sbjct: 3013 P-VIEYGTVNGTDFDCGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHCEHTSCGSLP 3071
Query: 651 TLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPI 710
+P + ++ +VI YSC + Y + G CTE+ WS P CE + C P
Sbjct: 3072 MIPNAFIS--ETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPLSCGSP- 3128
Query: 711 VAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGES-LSTCED 769
S+ + +H TY + VK RC +GY + ++ TC+
Sbjct: 3129 ---PSVANAVATGEAH---------------TYE--SEVKLRCLEGYTMDTDTDTFTCQK 3168
Query: 770 NGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQE 829
+G+W +C C P I + + + + C E + EGV +CQ
Sbjct: 3169 DGRWFPERISCSPKKCPLPENITH--ILVHGDDFSVNRQVSVSCAEGYTFEGVNISVCQL 3226
Query: 830 NGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTC 889
+GTW EPP E P + ++ VV S + YQCE GY L+G++ R C
Sbjct: 3227 DGTW--EPPFSDESCSPVSCGKPESPEHGFVVGSKYTFESTIIYQCEPGYELEGNRERVC 3284
Query: 890 ISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKC 949
QW+G V +C C + NGK I N +T G +V Y C Y GP C
Sbjct: 3285 QENRQWSGGVAICKETRCETQLEFLNGKADIENRTT--GPNVVYSCNRGYSLEGPSEAHC 3342
Query: 950 LDDGRWSGEEPSCE 963
++G WS P C+
Sbjct: 3343 TENGTWSHPVPLCK 3356
Score = 292 bits (717), Expect = 4e-78
Identities = 180/620 (29%), Positives = 268/620 (43%), Gaps = 50/620 (8%)
Query: 353 CGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCG 412
C P N + + +GS + Y C GH+L G R C ++ WSGA P C+ ++C
Sbjct: 2720 CDLPTAPENGFLRFTETSMGSAVQYSCKPGHILAGSDLRLCLENRKWSGASPRCEAISCK 2779
Query: 413 GLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCP 472
P+ +G + + T+ + Y C + L G RTC D+ WD + P C+ C
Sbjct: 2780 KPNPVMNGSIK--GSNYTYLSTLYYECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDCS 2837
Query: 473 DPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTP 532
PP +N V + + YTC G +L G+ S C G+WSG P C V C TP
Sbjct: 2838 SPPVSANGQVRGDEYTFQKEIEYTCNEGFLLEGARSRVCLANGSWSGATPDCVPVRCATP 2897
Query: 533 TIHKGSFVLINGTT---TYGSIAQ--FTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTS 587
L NG T YG + + F C Y L+GA +L C DG W +IP C+ +
Sbjct: 2898 P------QLANGVTEGLDYGFMKEVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCKPVN 2951
Query: 588 CPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCG 647
C PE + G+ F + I + C G+KL G + C +G WSG SP+C C
Sbjct: 2952 CGPPEDLAHGFPNGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCLPCRC- 3010
Query: 648 KLPTLPYGTMELLNGTT-HLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRC 706
P + YGT +NGT G + C ++L+G TC + QWS P CE C
Sbjct: 3011 STPVIEYGT---VNGTDFDCGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHCEHTSC 3067
Query: 707 SDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLST 766
+ + +S T + + + ++ Y C GY + G S
Sbjct: 3068 GSLPMIPNAFISETSSWKEN---------------------VITYSCRSGYVIQGSSDLI 3106
Query: 767 CEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELE-GVIRR 825
C + G WS P C+ + CG+P + N T A Y + +C E + ++
Sbjct: 3107 CTEKGVWSQPYPVCEPLSCGSPPSVANAVAT--GEAHTYESEVKLRCLEGYTMDTDTDTF 3164
Query: 826 MCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQ 885
CQ++G W E C CP P + + +LV S+ + C GY +G
Sbjct: 3165 TCQKDGRWFPERISCSPKKCPLP----ENITHILVHGDDFSVNRQVSVSCAEGYTFEGVN 3220
Query: 886 TRTCISKGQWNG--TVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVG 943
C G W + C P+ C P + E+G +V S + F S++ Y C Y+ G
Sbjct: 3221 ISVCQLDGTWEPPFSDESCSPVSCGKPESPEHGFVVGSKYT--FESTIIYQCEPGYELEG 3278
Query: 944 PFLRKCLDDGRWSGEEPSCE 963
R C ++ +WSG C+
Sbjct: 3279 NRERVCQENRQWSGGVAICK 3298
Score = 291 bits (714), Expect = 9e-78
Identities = 176/586 (30%), Positives = 255/586 (43%), Gaps = 38/586 (6%)
Query: 372 GSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRTTH 431
G+ + Y C G+ LLG+ C++DG W+G+ PSC + C T E+G + + T+
Sbjct: 2681 GTMVSYTCNPGYELLGNPVLICQEDGTWNGSAPSCISIECDLPTAPENGFLRFTE--TSM 2738
Query: 432 GARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGS 491
G+ YSC+ L G+ R C + W G +PRC C P V N S+ + + S
Sbjct: 2739 GSAVQYSCKPGHILAGSDLRLCLENRKWSGASPRCEAISCKKPNPVMNGSIKGSNYTYLS 2798
Query: 492 LASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTIHKGSFVLINGTTTYGSI 551
Y C+ G++L+G+ TC W P C V+C +P + V T+
Sbjct: 2799 TLYYECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDCSSPPVSANGQVR-GDEYTFQKE 2857
Query: 552 AQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFDYYVHSTIN 611
++TC + L GA VC +G WS P C C P + G E DY +
Sbjct: 2858 IEYTCNEGFLLEGARSRVCLANGSWSGATPDCVPVRCATPPQLANGVTEGLDYGFMKEVT 2917
Query: 612 FHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHL-GSVI 670
FHC G+ L G P L CQ DG W + P C+ ++CG L +G NG + + G I
Sbjct: 2918 FHCHEGYILHGAPKLTCQSDGNWDAEIPLCKPVNCGPPEDLAHG---FPNGFSFIHGGHI 2974
Query: 671 QYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTL 730
QY C Y+L G R C WS SSP C RCS P++ +V G D
Sbjct: 2975 QYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCLPCRCSTPVI---EYGTVNGTD------- 3024
Query: 731 IRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGR 790
D G RI +C KG+K++G S TCE +GQWS P C++ CG+
Sbjct: 3025 ------FDCGKAARI------QCFKGFKLLGLSEITCEADGQWSSGFPHCEHTSCGSLPM 3072
Query: 791 IENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSA 850
I N ++ +++ Y C + ++G +C E G WS P+C+ ++C P +
Sbjct: 3073 IPNAFIS--ETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPLSCGSPPS 3130
Query: 851 QIKAGSGLLVVTSTLSIGGEAHYQCERGYNL-KGHQTRTCISKGQWNGTVPVCIPIDCRS 909
A + + E +C GY + T TC G+W C P C
Sbjct: 3131 VANA----VATGEAHTYESEVKLRCLEGYTMDTDTDTFTCQKDGRWFPERISCSPKKCPL 3186
Query: 910 PGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRW 955
P NI + I++ V C Y G + C DG W
Sbjct: 3187 PENITH--ILVHGDDFSVNRQVSVSCAEGYTFEGVNISVCQLDGTW 3230
Score = 280 bits (687), Expect = 2e-74
Identities = 183/621 (29%), Positives = 269/621 (43%), Gaps = 43/621 (6%)
Query: 349 LPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKY 408
+P C SP N + G++Y I Y C EG +L G +SR C +G WSGA P C
Sbjct: 2832 IPVDCSSPPVSANGQVRGDEYTFQKEIEYTCNEGFLLEGARSRVCLANGSWSGATPDCVP 2891
Query: 409 VNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLF 468
V C + +G +D + C E + L G P+ TC +G WD E P C
Sbjct: 2892 VRCATPPQLANGVTEGLDYGFMK--EVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCKP 2949
Query: 469 DWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVN 528
C P +++ G Y C G+ L G++S C G+WSG PSC
Sbjct: 2950 VNCGPPEDLAHGFPNGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCLPCR 3009
Query: 529 CGTPTIHKGSFVLINGTT-TYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTS 587
C TP I G+ +NGT G A+ C + L G E+ C DG+WS P CE TS
Sbjct: 3010 CSTPVIEYGT---VNGTDFDCGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHCEHTS 3066
Query: 588 CPE-PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDC 646
C P +P+ ++ + + I + C +G+ + G +L+C + G WS P CE + C
Sbjct: 3067 CGSLPMIPN-AFISETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPLSC 3125
Query: 647 GKLPTLPYGTMELLNGTTH-LGSVIQYSCTTNYRL-VGPVRRTCTEEFQWSDSSPRCEEI 704
G P++ + G H S ++ C Y + TC ++ +W C
Sbjct: 3126 GSPPSV---ANAVATGEAHTYESEVKLRCLEGYTMDTDTDTFTCQKDGRWFPERISCSPK 3182
Query: 705 RCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESL 764
+C P ++T H L+ G+ + + V C +GY G ++
Sbjct: 3183 KCPLP-------ENIT-------HILVH-------GDDFSVNRQVSVSCAEGYTFEGVNI 3221
Query: 765 STCEDNGQWSG--TTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGV 822
S C+ +G W + +C V CG P E+G V + S TF +T YQC+ +ELEG
Sbjct: 3222 SVCQLDGTWEPPFSDESCSPVSCGKPESPEHGFV-VGSKYTF-ESTIIYQCEPGYELEGN 3279
Query: 823 IRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLK 882
R+CQEN WS ICKE C Q++ +G + + + G Y C RGY+L+
Sbjct: 3280 RERVCQENRQWSGGVAICKETRC---ETQLEFLNGKADIENR-TTGPNVVYSCNRGYSLE 3335
Query: 883 GHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRV 942
G C G W+ VP+C P C P I + +S +V C +
Sbjct: 3336 GPSEAHCTENGTWSHPVPLCKPNPCPVPFVIPENAL-LSEKEFYVDQNVSIKCREGFLLQ 3394
Query: 943 GPFLRKCLDDGRWSGEEPSCE 963
G + D W+ CE
Sbjct: 3395 GHGIITYNPDETWTQTSAKCE 3415
Score = 266 bits (653), Expect = 2e-70
Identities = 169/600 (28%), Positives = 259/600 (43%), Gaps = 40/600 (6%)
Query: 372 GSRIVYKCPEGHMLLGDKSRHCKKDGFW---SGAP-PSCKYVNCGGLTPIEDGDVALIDN 427
G Y C +G+ L + C G W G P C C + + +
Sbjct: 2043 GDIAFYYCSDGYSLADNSQLLCNAQGKWVPPEGQDMPRCIAHFCEKPPSVSYSILESVSK 2102
Query: 428 -RTTHGARALYSCRENFTLVGNPERTCGDEGIWDGE--APRCLFDWCPDPPAVSNASVTV 484
+ G+ + C E F L + + C G W+ + +C+ C +PP++ N +
Sbjct: 2103 AKFAAGSVVSFKCMEGFVLNTSAKIECMRGGQWNPSPMSIQCIPVRCGEPPSIMNGYASG 2162
Query: 485 NGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTIHKGSFVLING 544
+ + G++ +Y+C G + G TC G WS P+C V+CG P + F+
Sbjct: 2163 SNYSFGAMVAYSCNKGFYIKGEKKSTCEATGQWSSPIPTCHPVSCGEPPKVENGFLEHTT 2222
Query: 545 TTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIP-SCELTSCPEPEVPSGGYMEAFD 603
+ S ++ C P Y G+ VC + W + P C C +P G+M+ +
Sbjct: 2223 GRIFESEVRYQCNPGYKSVGSPVFVCQANRHWHSESPLMCVPLDCGKPPPIQNGFMKGEN 2282
Query: 604 YYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDS-PTCEYIDCGKLPTLPYGTMELLNG 662
+ V S + F C G++L+G+ + CQ+ G+W+ S P C C + P L + L
Sbjct: 2283 FEVGSKVQFFCNEGYELVGDSSWTCQKSGKWNKKSNPKCMPAKCPEPPLLE-NQLVLKEL 2341
Query: 663 TTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGN 722
TT +G V+ +SC + L GP C QW+DS P C+ + C+ P +
Sbjct: 2342 TTEVG-VVTFSCKEGHVLQGPSVLKCLPSQQWNDSFPVCKIVLCTPPPLI---------- 2390
Query: 723 DRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQY 782
S G + + G+ VKY C G+ + G S + C+ +G WS P C
Sbjct: 2391 --SFGVPI--------PSSALHFGSTVKYSCVGGFFLRGNSTTLCQPDGTWSSPLPECVP 2440
Query: 783 VDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKE 842
V+C P I NG + + A Y +TA Y C +EL G +C ENG W P CK
Sbjct: 2441 VECPQPEEIPNGIIDVQGLA--YLSTALYTCKPGFELVGNTTTLCGENGHWLGGKPTCKA 2498
Query: 843 ITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVC 902
I C P + +G T L G Y C RG+ L+G TC+ G W+ P C
Sbjct: 2499 IECLKPKEIL---NGKFSYTD-LHYGQTVTYSCNRGFRLEGPSALTCLETGDWDVDAPSC 2554
Query: 903 IPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
I C SP IENG + +G+ + Y C +Q G ++ C + G WS P+C
Sbjct: 2555 NAIHCDSPQPIENG--FVEGADYSYGAIIIYSCFPGFQVAGHAMQTCEESG-WSSSIPTC 2611
Score = 266 bits (652), Expect = 3e-70
Identities = 174/621 (28%), Positives = 251/621 (40%), Gaps = 46/621 (7%)
Query: 349 LPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKY 408
+P C +P +L N G DY + + C EG++L G C+ DG W P CK
Sbjct: 2890 VPVRCATPPQLANGVTEGLDYGFMKEVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCKP 2949
Query: 409 VNCGGLTPIEDGDVALIDNRT-THGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL 467
VNCG P ED + + HG Y C + L GN R C G W G +P CL
Sbjct: 2950 VNCG---PPEDLAHGFPNGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCL 3006
Query: 468 FDWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYV 527
C P + +V G A C G L G + +TC G WS P C++
Sbjct: 3007 PCRC-STPVIEYGTVNGTDFDCGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHCEHT 3065
Query: 528 NCGTPTIHKGSFVLINGTTTYG-SIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELT 586
+CG+ + +F I+ T+++ ++ ++C Y + G+ +L+C G WS P CE
Sbjct: 3066 SCGSLPMIPNAF--ISETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPL 3123
Query: 587 SCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPN-LVCQQDGEWSGDSPTCEYID 645
SC P + + S + C G+ + + + CQ+DG W + +C
Sbjct: 3124 SCGSPPSVANAVATGEAHTYESEVKLRCLEGYTMDTDTDTFTCQKDGRWFPERISCSPKK 3183
Query: 646 CGKLPTLPYGTMELLNGTTH-LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSD--SSPRCE 702
C P T L++G + + SC Y G C + W S C
Sbjct: 3184 C---PLPENITHILVHGDDFSVNRQVSVSCAEGYTFEGVNISVCQLDGTWEPPFSDESCS 3240
Query: 703 EIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGE 762
+ C P E HG VG+ Y + + Y+CE GY++ G
Sbjct: 3241 PVSCGKPESPE------------HGFV---------VGSKYTFESTIIYQCEPGYELEGN 3279
Query: 763 SLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGV 822
C++N QWSG C+ C NGK + + T G Y C+ + LEG
Sbjct: 3280 RERVCQENRQWSGGVAICKETRCETQLEFLNGKADIENRTT--GPNVVYSCNRGYSLEGP 3337
Query: 823 IRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLK 882
C ENGTWS P+CK CP P L+ + +C G+ L+
Sbjct: 3338 SEAHCTENGTWSHPVPLCKPNPCPVP---FVIPENALLSEKEFYVDQNVSIKCREGFLLQ 3394
Query: 883 GHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRV 942
GH T W T C I C P ++EN + +G + Y C S Y
Sbjct: 3395 GHGIITYNPDETWTQTSAKCEKISCGPPAHVENA--IARGVHYQYGDMITYSCYSGYMLE 3452
Query: 943 GPFLRK-CLDDGRWSGEEPSC 962
G FLR CL++G W+ P C
Sbjct: 3453 G-FLRSVCLENGTWT-SPPIC 3471
Score = 266 bits (651), Expect = 4e-70
Identities = 165/537 (30%), Positives = 232/537 (43%), Gaps = 42/537 (7%)
Query: 431 HGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAG 490
+G Y+C + L+GNP C ++G W+G AP C+ C P A N + G
Sbjct: 2680 YGTMVSYTCNPGYELLGNPVLICQEDGTWNGSAPSCISIECDLPTAPENGFLRFTETSMG 2739
Query: 491 SLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPT-IHKGSFVLINGTT-TY 548
S Y+C+ GHIL+GS C WSG P C+ ++C P + GS I G+ TY
Sbjct: 2740 SAVQYSCKPGHILAGSDLRLCLENRKWSGASPRCEAISCKKPNPVMNGS---IKGSNYTY 2796
Query: 549 GSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFDYYVHS 608
S + C+P Y LNG E C D W D P C C P V + G + +Y
Sbjct: 2797 LSTLYYECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDCSSPPVSANGQVRGDEYTFQK 2856
Query: 609 TINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGS 668
I + C G L G + VC +G WSG +P C + C P L G E L+
Sbjct: 2857 EIEYTCNEGFLLEGARSRVCLANGSWSGATPDCVPVRCATPPQLANGVTEGLD--YGFMK 2914
Query: 669 VIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGH 728
+ + C Y L G + TC + W P C+ + C P D +HG
Sbjct: 2915 EVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCKPVNCGPP------------EDLAHGF 2962
Query: 729 TLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNP 788
G ++ G ++Y+C GYK+ G S C NG WSG++P+C C P
Sbjct: 2963 ---------PNGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCLPCRCSTP 3013
Query: 789 GRIENGKVTLPSNATFY--GATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCP 846
IE G V N T + G A QC + ++L G+ C+ +G WS P C+ +C
Sbjct: 3014 -VIEYGTV----NGTDFDCGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHCEHTSC- 3067
Query: 847 DPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPID 906
+ + + TS+ Y C GY ++G C KG W+ PVC P+
Sbjct: 3068 --GSLPMIPNAFISETSSWK-ENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPLS 3124
Query: 907 CRSPGNIENGKIVISNGSTLFGSSVEYYCLSQY-QRVGPFLRKCLDDGRWSGEEPSC 962
C SP ++ N V + + + S V+ CL Y C DGRW E SC
Sbjct: 3125 CGSPPSVANA--VATGEAHTYESEVKLRCLEGYTMDTDTDTFTCQKDGRWFPERISC 3179
Score = 248 bits (607), Expect = 8e-65
Identities = 145/505 (28%), Positives = 219/505 (43%), Gaps = 31/505 (6%)
Query: 347 QYLPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSC 406
Q +P CG P ++N G++Y G+ + Y C +G + G+K C+ G WS P+C
Sbjct: 2143 QCIPVRCGEPPSIMNGYASGSNYSFGAMVAYSCNKGFYIKGEKKSTCEATGQWSSPIPTC 2202
Query: 407 KYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAP-R 465
V+CG +E+G + R + Y C + VG+P C W E+P
Sbjct: 2203 HPVSCGEPPKVENGFLEHTTGRIFE-SEVRYQCNPGYKSVGSPVFVCQANRHWHSESPLM 2261
Query: 466 CLFDWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVP-PSC 524
C+ C PP + N + + GS + C G+ L G +S TC G W+ P C
Sbjct: 2262 CVPLDCGKPPPIQNGFMKGENFEVGSKVQFFCNEGYELVGDSSWTCQKSGKWNKKSNPKC 2321
Query: 525 KYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCE 584
C P + + VL TT G + F+C+ + L G L C +W+ P C+
Sbjct: 2322 MPAKCPEPPLLENQLVLKELTTEVG-VVTFSCKEGHVLQGPSVLKCLPSQQWNDSFPVCK 2380
Query: 585 LTSC-PEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEY 643
+ C P P + G + + + ST+ + C G L G +CQ DG WS P C
Sbjct: 2381 IVLCTPPPLISFGVPIPSSALHFGSTVKYSCVGGFFLRGNSTTLCQPDGTWSSPLPECVP 2440
Query: 644 IDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEE 703
++C + +P G ++ + G +L + + Y+C + LVG C E W P C+
Sbjct: 2441 VECPQPEEIPNGIID-VQGLAYLSTAL-YTCKPGFELVGNTTTLCGENGHWLGGKPTCKA 2498
Query: 704 IRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGES 763
I C P S T D +G T V Y C +G+++ G S
Sbjct: 2499 IECLKPKEILNGKFSYT--DLHYGQT-------------------VTYSCNRGFRLEGPS 2537
Query: 764 LSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVI 823
TC + G W P+C + C +P IENG V + YGA Y C +++ G
Sbjct: 2538 ALTCLETGDWDVDAPSCNAIHCDSPQPIENGFVEGADYS--YGAIIIYSCFPGFQVAGHA 2595
Query: 824 RRMCQENGTWSLEPPICKEITCPDP 848
+ C+E+G WS P C I C P
Sbjct: 2596 MQTCEESG-WSSSIPTCMPIDCGLP 2619
Score = 241 bits (589), Expect = 1e-62
Identities = 168/620 (27%), Positives = 259/620 (41%), Gaps = 63/620 (10%)
Query: 352 TCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVN- 410
+CG P L N +D+ GS + Y+C G+ LLGD C +G W+G PSC V+
Sbjct: 1692 SCGVPPPLENGFHSADDFYAGSTVTYQCNNGYYLLGDSRMFCTDNGSWNGVSPSCLDVDE 1751
Query: 411 CG-GLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFD 469
C G E +D + SC ++T G + C E +C
Sbjct: 1752 CAVGSDCSEHASCLNVD------GSYICSCVPSYTGDG---KNC-------AEPIKCK-- 1793
Query: 470 WCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNC 529
P P ++S + + G+ +++C+ G+ L G T +TC G W+ + P CK V+C
Sbjct: 1794 -APGNPENGHSSGEI--YTVGAEVTFSCQEGYQLMGVTKITCLESGEWNHLIPYCKAVSC 1850
Query: 530 GTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCP 589
G P I + + T+GS + C Y L G +E C + WS+ P CE C
Sbjct: 1851 GKPAIPENG-CIEELAFTFGSKVTYRCNKGYTLAGDKESSCLANSSWSHSPPVCEPVKCS 1909
Query: 590 EPE-VPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGK 648
PE + +G Y+ + Y+ ST ++ C+ G+ L G + C G W P C + CG+
Sbjct: 1910 SPENINNGKYILSGLTYL-STASYSCDTGYSLQGPSIIECTASGIWDRAPPACHLVFCGE 1968
Query: 649 LPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSD 708
P + + N T + + Y+C Y L G C + +WS S +C + C +
Sbjct: 1969 PPAIKDAVITGNNFT--FRNTVTYTCKEGYTLAGLDTIECLADGKWSRSDQQCLAVSCDE 2026
Query: 709 PIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCE 768
P + + + H L G + Y C GY + S C
Sbjct: 2027 PPIVDHA-------SPETAHRL--------------FGDIAFYYCSDGYSLADNSQLLCN 2065
Query: 769 DNGQW----SGTTPTCQYVDCGNPGRIENGKVTLPSNATF-YGATAFYQCDENWELEGVI 823
G+W P C C P + + S A F G+ ++C E + L
Sbjct: 2066 AQGKWVPPEGQDMPRCIAHFCEKPPSVSYSILESVSKAKFAAGSVVSFKCMEGFVLNTSA 2125
Query: 824 RRMCQENGTWSLEPPI--CKEITCPDPSAQIKA-GSGLLVVTSTLSIGGEAHYQCERGYN 880
+ C G W+ P C + C +P + + SG S S G Y C +G+
Sbjct: 2126 KIECMRGGQWNPSPMSIQCIPVRCGEPPSIMNGYASG-----SNYSFGAMVAYSCNKGFY 2180
Query: 881 LKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQ 940
+KG + TC + GQW+ +P C P+ C P +ENG + + G +F S V Y C Y+
Sbjct: 2181 IKGEKKSTCEATGQWSSPIPTCHPVSCGEPPKVENGFLEHTTG-RIFESEVRYQCNPGYK 2239
Query: 941 RVGPFLRKCLDDGRWSGEEP 960
VG + C + W E P
Sbjct: 2240 SVGSPVFVCQANRHWHSESP 2259
Score = 235 bits (574), Expect = 8e-61
Identities = 159/605 (26%), Positives = 253/605 (41%), Gaps = 62/605 (10%)
Query: 368 DYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDN 427
D GS++ C G L+G+ ++C G W+ P C+ ++CG P+E+G + D
Sbjct: 1650 DLKPGSKVNLFCDPGFQLVGNPVQYCLNQGQWTQPLPHCERISCGVPPPLENGFHSADDF 1709
Query: 428 RTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL-FDWCPDPPAVSNASVTVNG 486
G+ Y C + L+G+ C D G W+G +P CL D C
Sbjct: 1710 YA--GSTVTYQCNNGYYLLGDSRMFCTDNGSWNGVSPSCLDVDEC--------------- 1752
Query: 487 HKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSC-KYVNCGTPTIHKGSFVLINGT 545
++ S E+ L+ S C+ +++G +C + + C P +
Sbjct: 1753 ----AVGSDCSEHASCLNVDGSYICSCVPSYTGDGKNCAEPIKCKAPGNPENGH-SSGEI 1807
Query: 546 TTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFDYY 605
T G+ F+C+ Y L G ++ C G+W++ IP C+ SC +P +P G +E +
Sbjct: 1808 YTVGAEVTFSCQEGYQLMGVTKITCLESGEWNHLIPYCKAVSCGKPAIPENGCIEELAFT 1867
Query: 606 VHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTH 665
S + + C G+ L G+ C + WS P CE + C + G +L+G T+
Sbjct: 1868 FGSKVTYRCNKGYTLAGDKESSCLANSSWSHSPPVCEPVKCSSPENINNGKY-ILSGLTY 1926
Query: 666 LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRS 725
L S YSC T Y L GP CT W + P C + C +P + ++++
Sbjct: 1927 L-STASYSCDTGYSLQGPSIIECTASGIWDRAPPACHLVFCGEPPAIKDAVIT------- 1978
Query: 726 HGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDC 785
GN + V Y C++GY + G C +G+WS + C V C
Sbjct: 1979 --------------GNNFTFRNTVTYTCKEGYTLAGLDTIECLADGKWSRSDQQCLAVSC 2024
Query: 786 GNPGRIENGKVTLPSNA-TFYGATAFYQCDENWELEGVIRRMCQENGTW----SLEPPIC 840
P +++ P A +G AFY C + + L + +C G W + P C
Sbjct: 2025 DEPPIVDHAS---PETAHRLFGDIAFYYCSDGYSLADNSQLLCNAQGKWVPPEGQDMPRC 2081
Query: 841 KEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVP 900
C P + + V + + G ++C G+ L C+ GQWN + P
Sbjct: 2082 IAHFCEKPPS-VSYSILESVSKAKFAAGSVVSFKCMEGFVLNTSAKIECMRGGQWNPS-P 2139
Query: 901 V---CIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSG 957
+ CIP+ C P +I NG SN S FG+ V Y C + G C G+WS
Sbjct: 2140 MSIQCIPVRCGEPPSIMNGYASGSNYS--FGAMVAYSCNKGFYIKGEKKSTCEATGQWSS 2197
Query: 958 EEPSC 962
P+C
Sbjct: 2198 PIPTC 2202
Score = 158 bits (383), Expect = 1e-37
Identities = 122/483 (25%), Positives = 189/483 (39%), Gaps = 49/483 (10%)
Query: 352 TCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNC 411
+CGS + N I + I Y C G+++ G C + G WS P C+ ++C
Sbjct: 3066 SCGSLPMIPNAFISETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPLSC 3125
Query: 412 GGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPER-TCGDEGIWDGEAPRCLFDW 470
G +P + T+ + C E +T+ + + TC +G W E C
Sbjct: 3126 G--SPPSVANAVATGEAHTYESEVKLRCLEGYTMDTDTDTFTCQKDGRWFPERISCSPKK 3183
Query: 471 CPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPP----SCKY 526
CP P +++ V + S +C G+ G C L G W PP SC
Sbjct: 3184 CPLPENITHILVHGDDFSVNRQVSVSCAEGYTFEGVNISVCQLDGTWE--PPFSDESCSP 3241
Query: 527 VNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELT 586
V+CG P + FV + T+ S + CEP Y L G E VC + +WS + C+ T
Sbjct: 3242 VSCGKPESPEHGFV-VGSKYTFESTIIYQCEPGYELEGNRERVCQENRQWSGGVAICKET 3300
Query: 587 SCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDC 646
C G + + + + C G+ L G C ++G WS P C+ C
Sbjct: 3301 RCETQLEFLNGKADIENRTTGPNVVYSCNRGYSLEGPSEAHCTENGTWSHPVPLCKPNPC 3360
Query: 647 GKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRC 706
+P + L ++ + C + L G T + W+ +S +CE+I C
Sbjct: 3361 PVPFVIPENAL-LSEKEFYVDQNVSIKCREGFLLQGHGIITYNPDETWTQTSAKCEKISC 3419
Query: 707 SDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLST 766
P E +I G Y+ G ++ Y C GY + G S
Sbjct: 3420 GPPAHVENAIAR---------------------GVHYQYGDMITYSCYSGYMLEGFLRSV 3458
Query: 767 CEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRM 826
C +NG W+ + P C+ V C P +NG + NA C E W + R+
Sbjct: 3459 CLENGTWT-SPPICRAV-CRFP--CQNGGICQRPNAC--------SCPEGW-----MGRL 3501
Query: 827 CQE 829
C+E
Sbjct: 3502 CEE 3504
Score = 145 bits (352), Expect = 7e-34
Identities = 101/369 (27%), Positives = 143/369 (38%), Gaps = 13/369 (3%)
Query: 345 ICQYLPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRH-CKKDGFWSGAP 403
+C+ P +CGSP + N G + S + +C EG+ + D C+KDG W
Sbjct: 3119 VCE--PLSCGSPPSVANAVATGEAHTYESEVKLRCLEGYTMDTDTDTFTCQKDGRWFPER 3176
Query: 404 PSCKYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDG-- 461
SC C P + + + + + SC E +T G C +G W+
Sbjct: 3177 ISCSPKKCP--LPENITHILVHGDDFSVNRQVSVSCAEGYTFEGVNISVCQLDGTWEPPF 3234
Query: 462 EAPRCLFDWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVP 521
C C P + + V + + S Y CE G+ L G+ C WSG
Sbjct: 3235 SDESCSPVSCGKPESPEHGFVVGSKYTFESTIIYQCEPGYELEGNRERVCQENRQWSGGV 3294
Query: 522 PSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIP 581
CK C T I TT G ++C Y L G E C +G WS+ +P
Sbjct: 3295 AICKETRCETQLEFLNGKADIENRTT-GPNVVYSCNRGYSLEGPSEAHCTENGTWSHPVP 3353
Query: 582 SCELTSCPEPEV-PSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPT 640
C+ CP P V P + ++YV ++ C G L G + D W+ S
Sbjct: 3354 LCKPNPCPVPFVIPENALLSEKEFYVDQNVSIKCREGFLLQGHGIITYNPDETWTQTSAK 3413
Query: 641 CEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPR 700
CE I CG P G +I YSC + Y L G +R C E W+ S P
Sbjct: 3414 CEKISCG--PPAHVENAIARGVHYQYGDMITYSCYSGYMLEGFLRSVCLENGTWT-SPPI 3470
Query: 701 CEEIRCSDP 709
C + C P
Sbjct: 3471 CRAV-CRFP 3478
Score = 129 bits (311), Expect = 6e-29
Identities = 100/347 (28%), Positives = 147/347 (42%), Gaps = 38/347 (10%)
Query: 644 IDCGKLPTLPYGTMELLNGTTHL--GSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRC 701
I C P L L + L GS + C ++LVG + C + QW+ P C
Sbjct: 1629 IFCSDCPRLGGSVPHLRTASEDLKPGSKVNLFCDPGFQLVGNPVQYCLNQGQWTQPLPHC 1688
Query: 702 EEIRCSDPIVAEKSIVSV----TGNDRSH----GHTLIRTSDN--RDVG--NTYRIGALV 749
E I C P E S G+ ++ G+ L+ S D G N L
Sbjct: 1689 ERISCGVPPPLENGFHSADDFYAGSTVTYQCNNGYYLLGDSRMFCTDNGSWNGVSPSCLD 1748
Query: 750 KYRCEKG---------YKVIGESLSTCEDNGQWSGTTPTC-QYVDCGNPGRIENGKVTLP 799
C G V G + +C + ++G C + + C PG ENG
Sbjct: 1749 VDECAVGSDCSEHASCLNVDGSYICSCVPS--YTGDGKNCAEPIKCKAPGNPENGH---- 1802
Query: 800 SNATFY--GATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSG 857
S+ Y GA + C E ++L GV + C E+G W+ P CK ++C P+
Sbjct: 1803 SSGEIYTVGAEVTFSCQEGYQLMGVTKITCLESGEWNHLIPYCKAVSCGKPAIPENGCIE 1862
Query: 858 LLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGK 917
L T G + Y+C +GY L G + +C++ W+ + PVC P+ C SP NI NGK
Sbjct: 1863 ELAFT----FGSKVTYRCNKGYTLAGDKESSCLANSSWSHSPPVCEPVKCSSPENINNGK 1918
Query: 918 IVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCEL 964
++S G T + S+ Y C + Y GP + +C G W P+C L
Sbjct: 1919 YILS-GLT-YLSTASYSCDTGYSLQGPSIIECTASGIWDRAPPACHL 1963
Score = 76.6 bits (180), Expect = 5e-13
Identities = 44/163 (26%), Positives = 67/163 (41%), Gaps = 6/163 (3%)
Query: 752 RCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFY 811
RC G+ ++G S+ C NG WSG C+ C + + ++G ++ + Y T
Sbjct: 405 RCHPGFDLVGSSIILCLPNGLWSGLESYCRVRTCPHLRQPKHGHISCSTREMLYKTTCLV 464
Query: 812 QCDENWELEGVIRRMCQENGTWSLEPPICKEITCPD---PSAQIKAGSGLLVVTSTLSIG 868
CDE + LEG + CQ N W P C E C P I + G
Sbjct: 465 ACDEGYRLEGSDKLTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISPHN--CGKQPAKFG 522
Query: 869 GEAHYQCERGYNLKG-HQTRTCISKGQWNGTVPVCIPIDCRSP 910
+ C +G+ L G + C + G+WN V + D +P
Sbjct: 523 TICYVSCRQGFILSGVKEMLRCTTSGKWNVGVQAAVCKDVEAP 565
Score = 75.4 bits (177), Expect = 1e-12
Identities = 47/196 (23%), Positives = 76/196 (38%), Gaps = 7/196 (3%)
Query: 405 SCKYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAP 464
+C+ V+C L P E+G A C F LVG+ C G+W G
Sbjct: 372 TCELVHCPALKPPENGYFIQNTCNNHFNAACGVRCHPGFDLVGSSIILCLPNGLWSGLES 431
Query: 465 RCLFDWCPD--PPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPP 522
C CP P + S + + C+ G+ L GS +TC W G P
Sbjct: 432 YCRVRTCPHLRQPKHGHISCSTREMLYKTTCLVACDEGYRLEGSDKLTCQGNSQWDGPEP 491
Query: 523 SCKYVNCGTPTIHKGSFVLING----TTTYGSIAQFTCEPDYWLNGAEELV-CNRDGKWS 577
C +C T + K + + +G+I +C + L+G +E++ C GKW+
Sbjct: 492 RCVERHCSTFQMPKDVIISPHNCGKQPAKFGTICYVSCRQGFILSGVKEMLRCTTSGKWN 551
Query: 578 YDIPSCELTSCPEPEV 593
+ + P++
Sbjct: 552 VGVQAAVCKDVEAPQI 567
Score = 73.3 bits (172), Expect = 4e-12
Identities = 46/158 (29%), Positives = 67/158 (42%), Gaps = 8/158 (5%)
Query: 378 KCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRTTHGARALY 437
+C G L+G C +G WSG C+ C L + G ++ + L
Sbjct: 405 RCHPGFDLVGSSIILCLPNGLWSGLESYCRVRTCPHLRQPKHGHISCSTREMLYKTTCLV 464
Query: 438 SCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWC-----PDPPAVSNASVTVNGHKAGSL 492
+C E + L G+ + TC WDG PRC+ C P +S + K G++
Sbjct: 465 ACDEGYRLEGSDKLTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISPHNCGKQPAKFGTI 524
Query: 493 ASYTCENGHILSG-STSVTCTLGGAWS-GVPPS-CKYV 527
+C G ILSG + CT G W+ GV + CK V
Sbjct: 525 CYVSCRQGFILSGVKEMLRCTTSGKWNVGVQAAVCKDV 562
Score = 72.1 bits (169), Expect = 1e-11
Identities = 39/122 (31%), Positives = 57/122 (46%), Gaps = 2/122 (1%)
Query: 841 KEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVP 900
K I C D + L + L G + + C+ G+ L G+ + C+++GQW +P
Sbjct: 1627 KSIFCSDCPRLGGSVPHLRTASEDLKPGSKVNLFCDPGFQLVGNPVQYCLNQGQWTQPLP 1686
Query: 901 VCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEP 960
C I C P +ENG S GS+V Y C + Y +G C D+G W+G P
Sbjct: 1687 HCERISCGVPPPLENG--FHSADDFYAGSTVTYQCNNGYYLLGDSRMFCTDNGSWNGVSP 1744
Query: 961 SC 962
SC
Sbjct: 1745 SC 1746
Score = 70.9 bits (166), Expect = 2e-11
Identities = 43/155 (27%), Positives = 64/155 (41%), Gaps = 4/155 (2%)
Query: 566 EELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYM--EAFDYYVHSTINFHCEAGHKLIGE 623
E+ VC R+G + +CEL CP + P GY + + ++ C G L+G
Sbjct: 358 EDCVC-REG-YRASGQTCELVHCPALKPPENGYFIQNTCNNHFNAACGVRCHPGFDLVGS 415
Query: 624 PNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGP 683
++C +G WSG C C L +G + + +C YRL G
Sbjct: 416 SIILCLPNGLWSGLESYCRVRTCPHLRQPKHGHISCSTREMLYKTTCLVACDEGYRLEGS 475
Query: 684 VRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVS 718
+ TC QW PRC E CS + + I+S
Sbjct: 476 DKLTCQGNSQWDGPEPRCVERHCSTFQMPKDVIIS 510
Score = 62.1 bits (144), Expect = 1e-08
Identities = 47/206 (22%), Positives = 78/206 (37%), Gaps = 8/206 (3%)
Query: 498 ENGHILSGSTSVT-CTLGGAWSGVPPSCKYVNC-GTPTIHKGSFVLINGTTTYGSIAQFT 555
EN GSTS C + +C+ V+C G F+ + +
Sbjct: 346 ENHTSPPGSTSPEDCVCREGYRASGQTCELVHCPALKPPENGYFIQNTCNNHFNAACGVR 405
Query: 556 CEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAF--DYYVHSTINFH 613
C P + L G+ ++C +G WS C + +CP P G++ + +T
Sbjct: 406 CHPGFDLVGSSIILCLPNGLWSGLESYCRVRTCPHLRQPKHGHISCSTREMLYKTTCLVA 465
Query: 614 CEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCG--KLP-TLPYGTMELLNGTTHLGSVI 670
C+ G++L G L CQ + +W G P C C ++P + G++
Sbjct: 466 CDEGYRLEGSDKLTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISPHNCGKQPAKFGTIC 525
Query: 671 QYSCTTNYRLVGPVRR-TCTEEFQWS 695
SC + L G CT +W+
Sbjct: 526 YVSCRQGFILSGVKEMLRCTTSGKWN 551
Score = 59.7 bits (138), Expect = 6e-08
Identities = 48/194 (24%), Positives = 73/194 (37%), Gaps = 8/194 (4%)
Query: 767 CEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRM 826
C + + SG T C+ V C ENG + + A +C ++L G +
Sbjct: 362 CREGYRASGQT--CELVHCPALKPPENGYFIQNTCNNHFNAACGVRCHPGFDLVGSSIIL 419
Query: 827 CQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQT 886
C NG WS C+ TCP Q K G + T + C+ GY L+G
Sbjct: 420 CLPNGLWSGLESYCRVRTCPH-LRQPKHGH-ISCSTREMLYKTTCLVACDEGYRLEGSDK 477
Query: 887 RTCISKGQWNGTVPVCIPIDC---RSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVG 943
TC QW+G P C+ C + P ++ FG+ C + G
Sbjct: 478 LTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISPHNCGKQPAKFGTICYVSCRQGFILSG 537
Query: 944 -PFLRKCLDDGRWS 956
+ +C G+W+
Sbjct: 538 VKEMLRCTTSGKWN 551
Score = 46.0 bits (104), Expect = 7e-04
Identities = 19/57 (33%), Positives = 27/57 (47%), Gaps = 3/57 (5%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
CG PA+P N + E G+ Y C++GY L G ++ C W+ PP C
Sbjct: 1850 CGKPAIPENGCIE---ELAFTFGSKVTYRCNKGYTLAGDKESSCLANSSWSHSPPVC 1903
Score = 45.2 bits (102), Expect = 0.001
Identities = 23/89 (25%), Positives = 36/89 (40%)
Query: 874 QCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEY 933
+C G++L G C+ G W+G C C ++G I S L+ ++
Sbjct: 405 RCHPGFDLVGSSIILCLPNGLWSGLESYCRVRTCPHLRQPKHGHISCSTREMLYKTTCLV 464
Query: 934 YCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
C Y+ G C + +W G EP C
Sbjct: 465 ACDEGYRLEGSDKLTCQGNSQWDGPEPRC 493
Score = 40.7 bits (91), Expect = 0.028
Identities = 17/43 (39%), Positives = 20/43 (46%)
Query: 19 ENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTN 61
EN G VY C+ GY L G + CT G W+ P C N
Sbjct: 3316 ENRTTGPNVVYSCNRGYSLEGPSEAHCTENGTWSHPVPLCKPN 3358
Score = 40.3 bits (90), Expect = 0.037
Identities = 17/52 (32%), Positives = 24/52 (46%)
Query: 7 VPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
VPP + ++ AG+ Y+C+ GY L G + CT G W P C
Sbjct: 1695 VPPPLENGFHSADDFYAGSTVTYQCNNGYYLLGDSRMFCTDNGSWNGVSPSC 1746
Score = 40.3 bits (90), Expect = 0.037
Identities = 23/67 (34%), Positives = 30/67 (44%), Gaps = 4/67 (5%)
Query: 14 SIPNEENIVAG----TIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTNVAFRKPAN 69
+I N + I++G + A Y CD GY L G ECT G W PP C PA
Sbjct: 1913 NINNGKYILSGLTYLSTASYSCDTGYSLQGPSIIECTASGIWDRAPPACHLVFCGEPPAI 1972
Query: 70 QSTTVRG 76
+ + G
Sbjct: 1973 KDAVITG 1979
Score = 39.1 bits (87), Expect = 0.085
Identities = 22/68 (32%), Positives = 29/68 (42%), Gaps = 4/68 (5%)
Query: 1 RCGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGT 60
+C P P N S E G + C EGY+L G + C G+W P+C
Sbjct: 1791 KCKAPGNPENGHSS---GEIYTVGAEVTFSCQEGYQLMGVTKITCLESGEWNHLIPYCKA 1847
Query: 61 NVAFRKPA 68
V+ KPA
Sbjct: 1848 -VSCGKPA 1854
Score = 37.5 bits (83), Expect = 0.26
Identities = 19/78 (24%), Positives = 34/78 (43%)
Query: 889 CISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRK 948
C+ + + + C + C + ENG + + + F ++ C + VG +
Sbjct: 360 CVCREGYRASGQTCELVHCPALKPPENGYFIQNTCNNHFNAACGVRCHPGFDLVGSSIIL 419
Query: 949 CLDDGRWSGEEPSCELAT 966
CL +G WSG E C + T
Sbjct: 420 CLPNGLWSGLESYCRVRT 437
Score = 37.5 bits (83), Expect = 0.26
Identities = 23/77 (29%), Positives = 29/77 (37%), Gaps = 7/77 (9%)
Query: 8 PPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTNVAFRKP 67
P + PN + + G Y+C GY+L G R C G W+ P C P
Sbjct: 2955 PEDLAHGFPNGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSC-------LP 3007
Query: 68 ANQSTTVRGGAAANGND 84
ST V NG D
Sbjct: 3008 CRCSTPVIEYGTVNGTD 3024
Score = 37.1 bits (82), Expect = 0.34
Identities = 16/58 (27%), Positives = 26/58 (44%), Gaps = 3/58 (5%)
Query: 1 RCGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
RCG P P+ + N G + Y C++G+ + G ++ C G W+ P C
Sbjct: 2148 RCGEP---PSIMNGYASGSNYSFGAMVAYSCNKGFYIKGEKKSTCEATGQWSSPIPTC 2202
Score = 37.1 bits (82), Expect = 0.34
Identities = 21/57 (36%), Positives = 26/57 (45%), Gaps = 3/57 (5%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C P V N +V +E I Y C+EG+ L GAR R C G W+ P C
Sbjct: 2836 CSSPPVSANGQVR--GDEYTFQKEIE-YTCNEGFLLEGARSRVCLANGSWSGATPDC 2889
Score = 35.9 bits (79), Expect = 0.79
Identities = 17/48 (35%), Positives = 22/48 (45%)
Query: 29 YECDEGYELFGARQRECTLRGDWTLEPPFCGTNVAFRKPANQSTTVRG 76
YECD GY L G +R C +W + P C P + + VRG
Sbjct: 2802 YECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDCSSPPVSANGQVRG 2849
Score = 34.7 bits (76), Expect = 1.8
Identities = 15/42 (35%), Positives = 19/42 (45%)
Query: 17 NEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
+ N + GT+ Y C+ GYEL G C G W P C
Sbjct: 2674 HSSNFLYGTMVSYTCNPGYELLGNPVLICQEDGTWNGSAPSC 2715
Score = 34.7 bits (76), Expect = 1.8
Identities = 21/57 (36%), Positives = 24/57 (42%), Gaps = 4/57 (7%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
CG PA NA I + G + Y C GY L G + C G WT PP C
Sbjct: 3419 CGPPAHVENA---IARGVHYQYGDMITYSCYSGYMLEGFLRSVCLENGTWT-SPPIC 3471
Score = 34.3 bits (75), Expect = 2.4
Identities = 18/57 (31%), Positives = 23/57 (40%), Gaps = 1/57 (1%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C H P + +S E + T V CDEGY L G+ + C W P C
Sbjct: 438 CPHLRQPKHGHISCSTREMLYKTTCLV-ACDEGYRLEGSDKLTCQGNSQWDGPEPRC 493
Score = 34.3 bits (75), Expect = 2.4
Identities = 18/57 (31%), Positives = 26/57 (45%), Gaps = 3/57 (5%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
CG + PNA +S E + + Y C GY + G+ CT +G W+ P C
Sbjct: 3067 CGSLPMIPNAFIS---ETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVC 3120
Score = 34.3 bits (75), Expect = 2.4
Identities = 18/51 (35%), Positives = 25/51 (49%), Gaps = 3/51 (5%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWT 52
CG P P + V + TI +Y+C+ GYEL G R+R C W+
Sbjct: 3244 CGKPESPEHGFVV--GSKYTFESTI-IYQCEPGYELEGNRERVCQENRQWS 3291
Score = 33.5 bits (73), Expect = 4.2
Identities = 12/35 (34%), Positives = 16/35 (45%)
Query: 24 GTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
G Y C+ G+ L G C GDW ++ P C
Sbjct: 2520 GQTVTYSCNRGFRLEGPSALTCLETGDWDVDAPSC 2554
Score = 33.5 bits (73), Expect = 4.2
Identities = 13/30 (43%), Positives = 16/30 (53%)
Query: 29 YECDEGYELFGARQRECTLRGDWTLEPPFC 58
+ C EGY L GA + C G+W E P C
Sbjct: 2918 FHCHEGYILHGAPKLTCQSDGNWDAEIPLC 2947
Score = 33.1 bits (72), Expect = 5.6
Identities = 17/49 (34%), Positives = 22/49 (44%), Gaps = 2/49 (4%)
Query: 8 PPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPP 56
PP + P + + G IA Y C +GY L Q C +G W PP
Sbjct: 2027 PPIVDHASPETAHRLFGDIAFYYCSDGYSLADNSQLLCNAQGKWV--PP 2073
Score = 33.1 bits (72), Expect = 5.6
Identities = 15/44 (34%), Positives = 19/44 (43%)
Query: 8 PPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDW 51
PP + EN G+ + C+EGYEL G C G W
Sbjct: 2270 PPPIQNGFMKGENFEVGSKVQFFCNEGYELVGDSSWTCQKSGKW 2313
Score = 32.7 bits (71), Expect = 7.4
Identities = 15/51 (29%), Positives = 19/51 (37%)
Query: 8 PPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
PP + ++ N Y C EGY L G EC G W+ C
Sbjct: 1969 PPAIKDAVITGNNFTFRNTVTYTCKEGYTLAGLDTIECLADGKWSRSDQQC 2019
>AY916667-1|AAX12481.1| 1497|Homo sapiens CCP module-containing
protein protein.
Length = 1497
Score = 312 bits (766), Expect = 5e-84
Identities = 187/641 (29%), Positives = 283/641 (44%), Gaps = 41/641 (6%)
Query: 349 LPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSG-APPSCK 407
+P CG P + N + G +++VGS++ + C EG+ L+GD S C+K G W+ + P C
Sbjct: 186 VPLDCGKPPPIQNGFMKGENFEVGSKVQFFCNEGYELVGDSSWTCQKSGKWNKKSNPKCM 245
Query: 408 YVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL 467
C P+ + + L + T G +SC+E L G C W+ P C
Sbjct: 246 PAKCPE-PPLLENQLVLKELTTEVGV-VTFSCKEGHVLQGPSVLKCLPSQQWNDSFPVCK 303
Query: 468 FDWCPDPPAVS-NASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKY 526
C PP +S + + GS Y+C G L G+++ C G WS P C
Sbjct: 304 IVLCTPPPLISFGVPIPSSALHFGSTVKYSCVGGFFLRGNSTTLCQPDGTWSSPLPECVP 363
Query: 527 VNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELT 586
V C P + + G Y S A +TC+P + L G +C +G W P+C+
Sbjct: 364 VECPQPEEIPNGIIDVQGLA-YLSTALYTCKPGFELVGNTTTLCGENGHWLGGKPTCKAI 422
Query: 587 SCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDC 646
C +P+ G D + T+ + C G +L G L C + G+W D+P+C I C
Sbjct: 423 ECLKPKEILNGKFSYTDLHYGQTVTYSCNRGFRLEGPSALTCLETGDWDVDAPSCNAIHC 482
Query: 647 GKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRC 706
+ G +E G++I YSC +++ G +TC EE WS S P C I C
Sbjct: 483 DSPQPIENGFVE--GADYSYGAIIIYSCFPGFQVAGHAMQTC-EESGWSSSIPTCMPIDC 539
Query: 707 SDP-----------------IVAEKSIVSV---TGNDRSHGHTLIRTSDNRDVG-----N 741
P E ++ V T + H + +T +N +
Sbjct: 540 GLPPHIDFGDCTKLKDDQGYFEQEDDMMEVPYVTPHPPYHLGAVAKTWENTKESPATHSS 599
Query: 742 TYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSN 801
+ G +V Y C GY+++G + C+++G W+G+ P+C ++C P ENG L
Sbjct: 600 NFLYGTMVSYTCNPGYELLGNPVLICQEDGTWNGSAPSCISIECDLPTAPENG--FLRFT 657
Query: 802 ATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVV 861
T G+ Y C L G R+C EN WS P C+ I+C P+ + GS +
Sbjct: 658 ETSMGSAVQYSCKPGHILAGSDLRLCLENRKWSGASPRCEAISCKKPN-PVMNGS---IK 713
Query: 862 TSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVIS 921
S + +Y+C+ GY L G + RTC W+ P+CIP+DC SP NG+ +
Sbjct: 714 GSNYTYLSTLYYECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDCSSPPVSANGQ--VR 771
Query: 922 NGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
F +EY C + G R CL +G WSG P C
Sbjct: 772 GDEYTFQKEIEYTCNEGFLLEGARSRVCLANGSWSGATPDC 812
Score = 297 bits (729), Expect = 1e-79
Identities = 180/617 (29%), Positives = 273/617 (44%), Gaps = 49/617 (7%)
Query: 350 PPTCGSPDKLLNTTILGNDYDV-GSRIVYKCPEGHMLLGDKSRHCKKDGFW-SGAPPSCK 407
P +CG P K+ N + + S + Y+C G+ +G C+ + W S +P C
Sbjct: 127 PVSCGEPPKVENGFLEHTTGRIFESEVRYQCNPGYKSVGSPVFVCQANRHWHSESPLMCV 186
Query: 408 YVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEA-PRC 466
++CG PI++G + G++ + C E + LVG+ TC G W+ ++ P+C
Sbjct: 187 PLDCGKPPPIQNGFMK--GENFEVGSKVQFFCNEGYELVGDSSWTCQKSGKWNKKSNPKC 244
Query: 467 LFDWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKY 526
+ CP+PP + N V + +++C+ GH+L G + + C W+ P CK
Sbjct: 245 MPAKCPEPPLLENQLVLKELTTEVGVVTFSCKEGHVLQGPSVLKCLPSQQWNDSFPVCKI 304
Query: 527 VNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELT 586
V C P + + + +GS +++C ++L G +C DG WS +P C
Sbjct: 305 VLCTPPPLISFGVPIPSSALHFGSTVKYSCVGGFFLRGNSTTLCQPDGTWSSPLPECVPV 364
Query: 587 SCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDC 646
CP+PE G ++ ST + C+ G +L+G +C ++G W G PTC+ I+C
Sbjct: 365 ECPQPEEIPNGIIDVQGLAYLSTALYTCKPGFELVGNTTTLCGENGHWLGGKPTCKAIEC 424
Query: 647 GKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRC 706
K + G + H G + YSC +RL GP TC E W +P C I C
Sbjct: 425 LKPKEILNGKFSYTD--LHYGQTVTYSCNRGFRLEGPSALTCLETGDWDVDAPSCNAIHC 482
Query: 707 SDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLST 766
P E V G Y GA++ Y C G++V G ++ T
Sbjct: 483 DSPQPIENGFVE---------------------GADYSYGAIIIYSCFPGFQVAGHAMQT 521
Query: 767 CEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRM 826
CE++G WS + PTC +DCG P I+ G T + Y F Q D+ E+ V
Sbjct: 522 CEESG-WSSSIPTCMPIDCGLPPHIDFGDCTKLKDDQGY----FEQEDDMMEVPYVTPHP 576
Query: 827 CQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQT 886
G + KE P+ +S G Y C GY L G+
Sbjct: 577 PYHLGAVAKTWENTKE----SPATH----------SSNFLYGTMVSYTCNPGYELLGNPV 622
Query: 887 RTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFL 946
C G WNG+ P CI I+C P ENG + + T GS+V+Y C + G L
Sbjct: 623 LICQEDGTWNGSAPSCISIECDLPTAPENGFLRFT--ETSMGSAVQYSCKPGHILAGSDL 680
Query: 947 RKCLDDGRWSGEEPSCE 963
R CL++ +WSG P CE
Sbjct: 681 RLCLENRKWSGASPRCE 697
Score = 296 bits (727), Expect = 2e-79
Identities = 186/614 (30%), Positives = 267/614 (43%), Gaps = 36/614 (5%)
Query: 352 TCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNC 411
+C P+ ++N +I G++Y S + Y+C G++L G + R C+ D W P C V+C
Sbjct: 700 SCKKPNPVMNGSIKGSNYTYLSTLYYECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDC 759
Query: 412 GGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWC 471
+G V + T Y+C E F L G R C G W G P C+ C
Sbjct: 760 SSPPVSANGQVR--GDEYTFQKEIEYTCNEGFLLEGARSRVCLANGSWSGATPDCVPVRC 817
Query: 472 PDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGT 531
PP ++N + ++ C G+IL G+ +TC G W P CK VNCG
Sbjct: 818 ATPPQLANGVTEGLDYGFMKEVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCKPVNCGP 877
Query: 532 PTIHKGSFVLING-TTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPE 590
P F NG + +G Q+ C P Y L+G C +G WS PSC C
Sbjct: 878 PEDLAHGFP--NGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCLPCRCST 935
Query: 591 PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLP 650
P V G + D+ C G KL+G + C+ DG+WS P CE+ CG LP
Sbjct: 936 P-VIEYGTVNGTDFDCGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHCEHTSCGSLP 994
Query: 651 TLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPI 710
+P + ++ +VI YSC + Y + G CTE+ WS P CE + C P
Sbjct: 995 MIPNAFIS--ETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPLSCGSP- 1051
Query: 711 VAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGES-LSTCED 769
S+ + +H TY + VK RC +GY + ++ TC+
Sbjct: 1052 ---PSVANAVATGEAH---------------TYE--SEVKLRCLEGYTMDTDTDTFTCQK 1091
Query: 770 NGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQE 829
+G+W +C C P I + + + + C E + EGV +CQ
Sbjct: 1092 DGRWFPERISCSPKKCPLPENITH--ILVHGDDFSVNRQVSVSCAEGYTFEGVNISVCQL 1149
Query: 830 NGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTC 889
+GTW EPP E P + ++ VV S + YQCE GY L+G++ R C
Sbjct: 1150 DGTW--EPPFSDESCSPVSCGKPESPEHGFVVGSKYTFESTIIYQCEPGYELEGNRERVC 1207
Query: 890 ISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKC 949
QW+G V +C C +P NGK I N +T G +V Y C Y GP C
Sbjct: 1208 QENRQWSGGVAICKETRCETPLEFLNGKADIENRTT--GPNVVYSCNRGYSLEGPSEAHC 1265
Query: 950 LDDGRWSGEEPSCE 963
++G WS P C+
Sbjct: 1266 TENGTWSHPVPLCK 1279
Score = 292 bits (717), Expect = 4e-78
Identities = 180/620 (29%), Positives = 268/620 (43%), Gaps = 50/620 (8%)
Query: 353 CGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCG 412
C P N + + +GS + Y C GH+L G R C ++ WSGA P C+ ++C
Sbjct: 643 CDLPTAPENGFLRFTETSMGSAVQYSCKPGHILAGSDLRLCLENRKWSGASPRCEAISCK 702
Query: 413 GLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCP 472
P+ +G + + T+ + Y C + L G RTC D+ WD + P C+ C
Sbjct: 703 KPNPVMNGSIK--GSNYTYLSTLYYECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDCS 760
Query: 473 DPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTP 532
PP +N V + + YTC G +L G+ S C G+WSG P C V C TP
Sbjct: 761 SPPVSANGQVRGDEYTFQKEIEYTCNEGFLLEGARSRVCLANGSWSGATPDCVPVRCATP 820
Query: 533 TIHKGSFVLINGTT---TYGSIAQ--FTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTS 587
L NG T YG + + F C Y L+GA +L C DG W +IP C+ +
Sbjct: 821 P------QLANGVTEGLDYGFMKEVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCKPVN 874
Query: 588 CPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCG 647
C PE + G+ F + I + C G+KL G + C +G WSG SP+C C
Sbjct: 875 CGPPEDLAHGFPNGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCLPCRC- 933
Query: 648 KLPTLPYGTMELLNGTT-HLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRC 706
P + YGT +NGT G + C ++L+G TC + QWS P CE C
Sbjct: 934 STPVIEYGT---VNGTDFDCGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHCEHTSC 990
Query: 707 SDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLST 766
+ + +S T + + + ++ Y C GY + G S
Sbjct: 991 GSLPMIPNAFISETSSWKEN---------------------VITYSCRSGYVIQGSSDLI 1029
Query: 767 CEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELE-GVIRR 825
C + G WS P C+ + CG+P + N T A Y + +C E + ++
Sbjct: 1030 CTEKGVWSQPYPVCEPLSCGSPPSVANAVAT--GEAHTYESEVKLRCLEGYTMDTDTDTF 1087
Query: 826 MCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQ 885
CQ++G W E C CP P + + +LV S+ + C GY +G
Sbjct: 1088 TCQKDGRWFPERISCSPKKCPLP----ENITHILVHGDDFSVNRQVSVSCAEGYTFEGVN 1143
Query: 886 TRTCISKGQWNG--TVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVG 943
C G W + C P+ C P + E+G +V S + F S++ Y C Y+ G
Sbjct: 1144 ISVCQLDGTWEPPFSDESCSPVSCGKPESPEHGFVVGSKYT--FESTIIYQCEPGYELEG 1201
Query: 944 PFLRKCLDDGRWSGEEPSCE 963
R C ++ +WSG C+
Sbjct: 1202 NRERVCQENRQWSGGVAICK 1221
Score = 291 bits (714), Expect = 9e-78
Identities = 176/586 (30%), Positives = 255/586 (43%), Gaps = 38/586 (6%)
Query: 372 GSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRTTH 431
G+ + Y C G+ LLG+ C++DG W+G+ PSC + C T E+G + + T+
Sbjct: 604 GTMVSYTCNPGYELLGNPVLICQEDGTWNGSAPSCISIECDLPTAPENGFLRFTE--TSM 661
Query: 432 GARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGS 491
G+ YSC+ L G+ R C + W G +PRC C P V N S+ + + S
Sbjct: 662 GSAVQYSCKPGHILAGSDLRLCLENRKWSGASPRCEAISCKKPNPVMNGSIKGSNYTYLS 721
Query: 492 LASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTIHKGSFVLINGTTTYGSI 551
Y C+ G++L+G+ TC W P C V+C +P + V T+
Sbjct: 722 TLYYECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDCSSPPVSANGQVR-GDEYTFQKE 780
Query: 552 AQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFDYYVHSTIN 611
++TC + L GA VC +G WS P C C P + G E DY +
Sbjct: 781 IEYTCNEGFLLEGARSRVCLANGSWSGATPDCVPVRCATPPQLANGVTEGLDYGFMKEVT 840
Query: 612 FHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHL-GSVI 670
FHC G+ L G P L CQ DG W + P C+ ++CG L +G NG + + G I
Sbjct: 841 FHCHEGYILHGAPKLTCQSDGNWDAEIPLCKPVNCGPPEDLAHG---FPNGFSFIHGGHI 897
Query: 671 QYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTL 730
QY C Y+L G R C WS SSP C RCS P++ +V G D
Sbjct: 898 QYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCLPCRCSTPVI---EYGTVNGTD------- 947
Query: 731 IRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGR 790
D G RI +C KG+K++G S TCE +GQWS P C++ CG+
Sbjct: 948 ------FDCGKAARI------QCFKGFKLLGLSEITCEADGQWSSGFPHCEHTSCGSLPM 995
Query: 791 IENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSA 850
I N ++ +++ Y C + ++G +C E G WS P+C+ ++C P +
Sbjct: 996 IPNAFIS--ETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPLSCGSPPS 1053
Query: 851 QIKAGSGLLVVTSTLSIGGEAHYQCERGYNL-KGHQTRTCISKGQWNGTVPVCIPIDCRS 909
A + + E +C GY + T TC G+W C P C
Sbjct: 1054 VANA----VATGEAHTYESEVKLRCLEGYTMDTDTDTFTCQKDGRWFPERISCSPKKCPL 1109
Query: 910 PGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRW 955
P NI + I++ V C Y G + C DG W
Sbjct: 1110 PENITH--ILVHGDDFSVNRQVSVSCAEGYTFEGVNISVCQLDGTW 1153
Score = 286 bits (701), Expect = 3e-76
Identities = 183/621 (29%), Positives = 267/621 (42%), Gaps = 43/621 (6%)
Query: 349 LPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKY 408
+P C SP N + G++Y I Y C EG +L G +SR C +G WSGA P C
Sbjct: 755 IPVDCSSPPVSANGQVRGDEYTFQKEIEYTCNEGFLLEGARSRVCLANGSWSGATPDCVP 814
Query: 409 VNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLF 468
V C + +G +D + C E + L G P+ TC +G WD E P C
Sbjct: 815 VRCATPPQLANGVTEGLDYGFMK--EVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCKP 872
Query: 469 DWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVN 528
C P +++ G Y C G+ L G++S C G+WSG PSC
Sbjct: 873 VNCGPPEDLAHGFPNGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCLPCR 932
Query: 529 CGTPTIHKGSFVLINGTT-TYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTS 587
C TP I G+ +NGT G A+ C + L G E+ C DG+WS P CE TS
Sbjct: 933 CSTPVIEYGT---VNGTDFDCGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHCEHTS 989
Query: 588 CPE-PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDC 646
C P +P+ ++ + + I + C +G+ + G +L+C + G WS P CE + C
Sbjct: 990 CGSLPMIPN-AFISETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPLSC 1048
Query: 647 GKLPTLPYGTMELLNGTTH-LGSVIQYSCTTNYRL-VGPVRRTCTEEFQWSDSSPRCEEI 704
G P++ + G H S ++ C Y + TC ++ +W C
Sbjct: 1049 GSPPSV---ANAVATGEAHTYESEVKLRCLEGYTMDTDTDTFTCQKDGRWFPERISCSPK 1105
Query: 705 RCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESL 764
+C P ++T H L+ G+ + + V C +GY G ++
Sbjct: 1106 KCPLP-------ENIT-------HILVH-------GDDFSVNRQVSVSCAEGYTFEGVNI 1144
Query: 765 STCEDNGQWSG--TTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGV 822
S C+ +G W + +C V CG P E+G V + S TF +T YQC+ +ELEG
Sbjct: 1145 SVCQLDGTWEPPFSDESCSPVSCGKPESPEHGFV-VGSKYTF-ESTIIYQCEPGYELEGN 1202
Query: 823 IRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLK 882
R+CQEN WS ICKE C P + + + + G Y C RGY+L+
Sbjct: 1203 RERVCQENRQWSGGVAICKETRCETPLEFLNGKADI----ENRTTGPNVVYSCNRGYSLE 1258
Query: 883 GHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRV 942
G C G W+ VP+C P C P I + +S +V C +
Sbjct: 1259 GPSEAHCTENGTWSHPVPLCKPNPCPVPFVIPENAL-LSEKEFYVDQNVSIKCREGFLLQ 1317
Query: 943 GPFLRKCLDDGRWSGEEPSCE 963
G + C D W+ CE
Sbjct: 1318 GHGIITCNPDETWTQTSAKCE 1338
Score = 274 bits (671), Expect = 1e-72
Identities = 176/621 (28%), Positives = 253/621 (40%), Gaps = 46/621 (7%)
Query: 349 LPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKY 408
+P C +P +L N G DY + + C EG++L G C+ DG W P CK
Sbjct: 813 VPVRCATPPQLANGVTEGLDYGFMKEVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCKP 872
Query: 409 VNCGGLTPIEDGDVALIDNRT-THGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL 467
VNCG P ED + + HG Y C + L GN R C G W G +P CL
Sbjct: 873 VNCG---PPEDLAHGFPNGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCL 929
Query: 468 FDWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYV 527
C P + +V G A C G L G + +TC G WS P C++
Sbjct: 930 PCRC-STPVIEYGTVNGTDFDCGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHCEHT 988
Query: 528 NCGTPTIHKGSFVLINGTTTYG-SIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELT 586
+CG+ + +F I+ T+++ ++ ++C Y + G+ +L+C G WS P CE
Sbjct: 989 SCGSLPMIPNAF--ISETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPL 1046
Query: 587 SCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPN-LVCQQDGEWSGDSPTCEYID 645
SC P + + S + C G+ + + + CQ+DG W + +C
Sbjct: 1047 SCGSPPSVANAVATGEAHTYESEVKLRCLEGYTMDTDTDTFTCQKDGRWFPERISCSPKK 1106
Query: 646 CGKLPTLPYGTMELLNGTTH-LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSD--SSPRCE 702
C P T L++G + + SC Y G C + W S C
Sbjct: 1107 C---PLPENITHILVHGDDFSVNRQVSVSCAEGYTFEGVNISVCQLDGTWEPPFSDESCS 1163
Query: 703 EIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGE 762
+ C P E HG VG+ Y + + Y+CE GY++ G
Sbjct: 1164 PVSCGKPESPE------------HGFV---------VGSKYTFESTIIYQCEPGYELEGN 1202
Query: 763 SLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGV 822
C++N QWSG C+ C P NGK + + T G Y C+ + LEG
Sbjct: 1203 RERVCQENRQWSGGVAICKETRCETPLEFLNGKADIENRTT--GPNVVYSCNRGYSLEGP 1260
Query: 823 IRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLK 882
C ENGTWS P+CK CP P L+ + +C G+ L+
Sbjct: 1261 SEAHCTENGTWSHPVPLCKPNPCPVP---FVIPENALLSEKEFYVDQNVSIKCREGFLLQ 1317
Query: 883 GHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRV 942
GH TC W T C I C P ++EN + +G + Y C S Y
Sbjct: 1318 GHGIITCNPDETWTQTSAKCEKISCGPPAHVENA--IARGVHYQYGDMITYSCYSGYMLE 1375
Query: 943 GPFLRK-CLDDGRWSGEEPSC 962
G FLR CL++G W+ P C
Sbjct: 1376 G-FLRSVCLENGTWT-SPPIC 1394
Score = 273 bits (670), Expect = 2e-72
Identities = 159/507 (31%), Positives = 244/507 (48%), Gaps = 39/507 (7%)
Query: 464 PRCLFDWCPDPPAVSNA---SVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGV 520
PRC+ +C PP+VS + SV+ AGS+ S+ C G +L+ S + C GG W+
Sbjct: 2 PRCIAHFCEKPPSVSYSILESVSKAKFAAGSVVSFKCMEGFVLNTSAKIECMRGGQWNPS 61
Query: 521 PPS--CKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSY 578
P S C V CG P + ++G++ ++C +++ G ++ C G+WS
Sbjct: 62 PMSIQCIPVRCGEPPSIMNGYA-SGSNYSFGAMVAYSCNKGFYIKGEKKSTCEATGQWSS 120
Query: 579 DIPSCELTSCPEPEVPSGGYME-AFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGD 637
IP+C SC EP G++E S + + C G+K +G P VCQ + W +
Sbjct: 121 PIPTCHPVSCGEPPKVENGFLEHTTGRIFESEVRYQCNPGYKSVGSPVFVCQANRHWHSE 180
Query: 638 SP-TCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWS- 695
SP C +DCGK P + G M+ N +GS +Q+ C Y LVG TC + +W+
Sbjct: 181 SPLMCVPLDCGKPPPIQNGFMKGEN--FEVGSKVQFFCNEGYELVGDSSWTCQKSGKWNK 238
Query: 696 DSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEK 755
S+P+C +C +P + E +V +++ T +G +V + C++
Sbjct: 239 KSNPKCMPAKCPEPPLLENQLVL------------------KEL--TTEVG-VVTFSCKE 277
Query: 756 GYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDE 815
G+ + G S+ C + QW+ + P C+ V C P I G V +PS+A +G+T Y C
Sbjct: 278 GHVLQGPSVLKCLPSQQWNDSFPVCKIVLCTPPPLISFG-VPIPSSALHFGSTVKYSCVG 336
Query: 816 NWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQC 875
+ L G +CQ +GTWS P C + CP P +I G ++ L+ A Y C
Sbjct: 337 GFFLRGNSTTLCQPDGTWSSPLPECVPVECPQPE-EIPNG---IIDVQGLAYLSTALYTC 392
Query: 876 ERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYC 935
+ G+ L G+ T C G W G P C I+C P I NGK S +G +V Y C
Sbjct: 393 KPGFELVGNTTTLCGENGHWLGGKPTCKAIECLKPKEILNGK--FSYTDLHYGQTVTYSC 450
Query: 936 LSQYQRVGPFLRKCLDDGRWSGEEPSC 962
++ GP CL+ G W + PSC
Sbjct: 451 NRGFRLEGPSALTCLETGDWDVDAPSC 477
Score = 266 bits (651), Expect = 4e-70
Identities = 165/537 (30%), Positives = 232/537 (43%), Gaps = 42/537 (7%)
Query: 431 HGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAG 490
+G Y+C + L+GNP C ++G W+G AP C+ C P A N + G
Sbjct: 603 YGTMVSYTCNPGYELLGNPVLICQEDGTWNGSAPSCISIECDLPTAPENGFLRFTETSMG 662
Query: 491 SLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPT-IHKGSFVLINGTT-TY 548
S Y+C+ GHIL+GS C WSG P C+ ++C P + GS I G+ TY
Sbjct: 663 SAVQYSCKPGHILAGSDLRLCLENRKWSGASPRCEAISCKKPNPVMNGS---IKGSNYTY 719
Query: 549 GSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFDYYVHS 608
S + C+P Y LNG E C D W D P C C P V + G + +Y
Sbjct: 720 LSTLYYECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDCSSPPVSANGQVRGDEYTFQK 779
Query: 609 TINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGS 668
I + C G L G + VC +G WSG +P C + C P L G E L+
Sbjct: 780 EIEYTCNEGFLLEGARSRVCLANGSWSGATPDCVPVRCATPPQLANGVTEGLD--YGFMK 837
Query: 669 VIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGH 728
+ + C Y L G + TC + W P C+ + C P D +HG
Sbjct: 838 EVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCKPVNCGPP------------EDLAHGF 885
Query: 729 TLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNP 788
G ++ G ++Y+C GYK+ G S C NG WSG++P+C C P
Sbjct: 886 ---------PNGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCLPCRCSTP 936
Query: 789 GRIENGKVTLPSNATFY--GATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCP 846
IE G V N T + G A QC + ++L G+ C+ +G WS P C+ +C
Sbjct: 937 -VIEYGTV----NGTDFDCGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHCEHTSC- 990
Query: 847 DPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPID 906
+ + + TS+ Y C GY ++G C KG W+ PVC P+
Sbjct: 991 --GSLPMIPNAFISETSSWK-ENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPLS 1047
Query: 907 CRSPGNIENGKIVISNGSTLFGSSVEYYCLSQY-QRVGPFLRKCLDDGRWSGEEPSC 962
C SP ++ N V + + + S V+ CL Y C DGRW E SC
Sbjct: 1048 CGSPPSVANA--VATGEAHTYESEVKLRCLEGYTMDTDTDTFTCQKDGRWFPERISC 1102
Score = 262 bits (641), Expect = 6e-69
Identities = 163/553 (29%), Positives = 232/553 (41%), Gaps = 37/553 (6%)
Query: 369 YDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPS--CKYVNCGGLTPIEDGDVALID 426
+ GS + +KC EG +L C + G W+ +P S C V CG I +G +
Sbjct: 28 FAAGSVVSFKCMEGFVLNTSAKIECMRGGQWNPSPMSIQCIPVRCGEPPSIMNGYAS--G 85
Query: 427 NRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVT-VN 485
+ + GA YSC + F + G + TC G W P C C +PP V N +
Sbjct: 86 SNYSFGAMVAYSCNKGFYIKGEKKSTCEATGQWSSPIPTCHPVSCGEPPKVENGFLEHTT 145
Query: 486 GHKAGSLASYTCENGHILSGSTSVTCTLGGAW-SGVPPSCKYVNCGTPTIHKGSFVLING 544
G S Y C G+ GS C W S P C ++CG P + F +
Sbjct: 146 GRIFESEVRYQCNPGYKSVGSPVFVCQANRHWHSESPLMCVPLDCGKPPPIQNGF-MKGE 204
Query: 545 TTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWS-YDIPSCELTSCPEPEVPSGGYMEAFD 603
GS QF C Y L G C + GKW+ P C CPEP + +
Sbjct: 205 NFEVGSKVQFFCNEGYELVGDSSWTCQKSGKWNKKSNPKCMPAKCPEPPLLENQLVLKEL 264
Query: 604 YYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGT 663
+ F C+ GH L G L C +W+ P C+ + C P + +G + + +
Sbjct: 265 TTEVGVVTFSCKEGHVLQGPSVLKCLPSQQWNDSFPVCKIVLCTPPPLISFG-VPIPSSA 323
Query: 664 THLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGND 723
H GS ++YSC + L G C + WS P C + C P I+ V
Sbjct: 324 LHFGSTVKYSCVGGFFLRGNSTTLCQPDGTWSSPLPECVPVECPQPEEIPNGIIDVQ--- 380
Query: 724 RSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYV 783
G Y AL Y C+ G++++G + + C +NG W G PTC+ +
Sbjct: 381 ----------------GLAYLSTAL--YTCKPGFELVGNTTTLCGENGHWLGGKPTCKAI 422
Query: 784 DCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEI 843
+C P I NGK + YG T Y C+ + LEG C E G W ++ P C I
Sbjct: 423 ECLKPKEILNGKFSYTD--LHYGQTVTYSCNRGFRLEGPSALTCLETGDWDVDAPSCNAI 480
Query: 844 TCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCI 903
C P I+ G V + S G Y C G+ + GH +TC G W+ ++P C+
Sbjct: 481 HCDSPQ-PIENG---FVEGADYSYGAIIIYSCFPGFQVAGHAMQTCEESG-WSSSIPTCM 535
Query: 904 PIDCRSPGNIENG 916
PIDC P +I+ G
Sbjct: 536 PIDCGLPPHIDFG 548
Score = 248 bits (607), Expect = 8e-65
Identities = 145/505 (28%), Positives = 219/505 (43%), Gaps = 31/505 (6%)
Query: 347 QYLPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSC 406
Q +P CG P ++N G++Y G+ + Y C +G + G+K C+ G WS P+C
Sbjct: 66 QCIPVRCGEPPSIMNGYASGSNYSFGAMVAYSCNKGFYIKGEKKSTCEATGQWSSPIPTC 125
Query: 407 KYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAP-R 465
V+CG +E+G + R + Y C + VG+P C W E+P
Sbjct: 126 HPVSCGEPPKVENGFLEHTTGRIFE-SEVRYQCNPGYKSVGSPVFVCQANRHWHSESPLM 184
Query: 466 CLFDWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVP-PSC 524
C+ C PP + N + + GS + C G+ L G +S TC G W+ P C
Sbjct: 185 CVPLDCGKPPPIQNGFMKGENFEVGSKVQFFCNEGYELVGDSSWTCQKSGKWNKKSNPKC 244
Query: 525 KYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCE 584
C P + + VL TT G + F+C+ + L G L C +W+ P C+
Sbjct: 245 MPAKCPEPPLLENQLVLKELTTEVG-VVTFSCKEGHVLQGPSVLKCLPSQQWNDSFPVCK 303
Query: 585 LTSC-PEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEY 643
+ C P P + G + + + ST+ + C G L G +CQ DG WS P C
Sbjct: 304 IVLCTPPPLISFGVPIPSSALHFGSTVKYSCVGGFFLRGNSTTLCQPDGTWSSPLPECVP 363
Query: 644 IDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEE 703
++C + +P G ++ + G +L + + Y+C + LVG C E W P C+
Sbjct: 364 VECPQPEEIPNGIID-VQGLAYLSTAL-YTCKPGFELVGNTTTLCGENGHWLGGKPTCKA 421
Query: 704 IRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGES 763
I C P S T D +G T V Y C +G+++ G S
Sbjct: 422 IECLKPKEILNGKFSYT--DLHYGQT-------------------VTYSCNRGFRLEGPS 460
Query: 764 LSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVI 823
TC + G W P+C + C +P IENG V + YGA Y C +++ G
Sbjct: 461 ALTCLETGDWDVDAPSCNAIHCDSPQPIENGFVEGADYS--YGAIIIYSCFPGFQVAGHA 518
Query: 824 RRMCQENGTWSLEPPICKEITCPDP 848
+ C+E+G WS P C I C P
Sbjct: 519 MQTCEESG-WSSSIPTCMPIDCGLP 542
Score = 165 bits (402), Expect = 6e-40
Identities = 124/483 (25%), Positives = 191/483 (39%), Gaps = 49/483 (10%)
Query: 352 TCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNC 411
+CGS + N I + I Y C G+++ G C + G WS P C+ ++C
Sbjct: 989 SCGSLPMIPNAFISETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPLSC 1048
Query: 412 GGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPER-TCGDEGIWDGEAPRCLFDW 470
G +P + T+ + C E +T+ + + TC +G W E C
Sbjct: 1049 G--SPPSVANAVATGEAHTYESEVKLRCLEGYTMDTDTDTFTCQKDGRWFPERISCSPKK 1106
Query: 471 CPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPP----SCKY 526
CP P +++ V + S +C G+ G C L G W PP SC
Sbjct: 1107 CPLPENITHILVHGDDFSVNRQVSVSCAEGYTFEGVNISVCQLDGTWE--PPFSDESCSP 1164
Query: 527 VNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELT 586
V+CG P + FV + T+ S + CEP Y L G E VC + +WS + C+ T
Sbjct: 1165 VSCGKPESPEHGFV-VGSKYTFESTIIYQCEPGYELEGNRERVCQENRQWSGGVAICKET 1223
Query: 587 SCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDC 646
C P G + + + + C G+ L G C ++G WS P C+ C
Sbjct: 1224 RCETPLEFLNGKADIENRTTGPNVVYSCNRGYSLEGPSEAHCTENGTWSHPVPLCKPNPC 1283
Query: 647 GKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRC 706
+P + L ++ + C + L G TC + W+ +S +CE+I C
Sbjct: 1284 PVPFVIPENAL-LSEKEFYVDQNVSIKCREGFLLQGHGIITCNPDETWTQTSAKCEKISC 1342
Query: 707 SDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLST 766
P E +I G Y+ G ++ Y C GY + G S
Sbjct: 1343 GPPAHVENAIAR---------------------GVHYQYGDMITYSCYSGYMLEGFLRSV 1381
Query: 767 CEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRM 826
C +NG W+ + P C+ V C P +NG + NA C E W + R+
Sbjct: 1382 CLENGTWT-SPPICRAV-CRFP--CQNGGICQRPNAC--------SCPEGW-----MGRL 1424
Query: 827 CQE 829
C+E
Sbjct: 1425 CEE 1427
Score = 162 bits (394), Expect = 5e-39
Identities = 106/390 (27%), Positives = 167/390 (42%), Gaps = 36/390 (9%)
Query: 580 IPSCELTSCPEPEVPSGGYMEAFD---YYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSG 636
+P C C +P S +E+ + S ++F C G L + C + G+W+
Sbjct: 1 MPRCIAHFCEKPPSVSYSILESVSKAKFAAGSVVSFKCMEGFVLNTSAKIECMRGGQWNP 60
Query: 637 D--SPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQW 694
S C + CG+ P++ G N + G+++ YSC + + G + TC QW
Sbjct: 61 SPMSIQCIPVRCGEPPSIMNGYASGSNYS--FGAMVAYSCNKGFYIKGEKKSTCEATGQW 118
Query: 695 SDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCE 754
S P C + C +P E + HT R ++ V+Y+C
Sbjct: 119 SSPIPTCHPVSCGEPPKVENGFLE---------HTTGRIFESE-----------VRYQCN 158
Query: 755 KGYKVIGESLSTCEDNGQWSGTTP-TCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQC 813
GYK +G + C+ N W +P C +DCG P I+NG + G+ + C
Sbjct: 159 PGYKSVGSPVFVCQANRHWHSESPLMCVPLDCGKPPPIQNG--FMKGENFEVGSKVQFFC 216
Query: 814 DENWELEGVIRRMCQENGTWSLEP-PICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAH 872
+E +EL G CQ++G W+ + P C CP+P LV+ + G
Sbjct: 217 NEGYELVGDSSWTCQKSGKWNKKSNPKCMPAKCPEPPLL----ENQLVLKELTTEVGVVT 272
Query: 873 YQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVE 932
+ C+ G+ L+G C+ QWN + PVC + C P I G + I + + FGS+V+
Sbjct: 273 FSCKEGHVLQGPSVLKCLPSQQWNDSFPVCKIVLCTPPPLISFG-VPIPSSALHFGSTVK 331
Query: 933 YYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
Y C+ + G C DG WS P C
Sbjct: 332 YSCVGGFFLRGNSTTLCQPDGTWSSPLPEC 361
Score = 153 bits (371), Expect = 3e-36
Identities = 103/369 (27%), Positives = 145/369 (39%), Gaps = 13/369 (3%)
Query: 345 ICQYLPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRH-CKKDGFWSGAP 403
+C+ P +CGSP + N G + S + +C EG+ + D C+KDG W
Sbjct: 1042 VCE--PLSCGSPPSVANAVATGEAHTYESEVKLRCLEGYTMDTDTDTFTCQKDGRWFPER 1099
Query: 404 PSCKYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDG-- 461
SC C P + + + + + SC E +T G C +G W+
Sbjct: 1100 ISCSPKKCP--LPENITHILVHGDDFSVNRQVSVSCAEGYTFEGVNISVCQLDGTWEPPF 1157
Query: 462 EAPRCLFDWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVP 521
C C P + + V + + S Y CE G+ L G+ C WSG
Sbjct: 1158 SDESCSPVSCGKPESPEHGFVVGSKYTFESTIIYQCEPGYELEGNRERVCQENRQWSGGV 1217
Query: 522 PSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIP 581
CK C TP I TT G ++C Y L G E C +G WS+ +P
Sbjct: 1218 AICKETRCETPLEFLNGKADIENRTT-GPNVVYSCNRGYSLEGPSEAHCTENGTWSHPVP 1276
Query: 582 SCELTSCPEPEV-PSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPT 640
C+ CP P V P + ++YV ++ C G L G + C D W+ S
Sbjct: 1277 LCKPNPCPVPFVIPENALLSEKEFYVDQNVSIKCREGFLLQGHGIITCNPDETWTQTSAK 1336
Query: 641 CEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPR 700
CE I CG P G +I YSC + Y L G +R C E W+ S P
Sbjct: 1337 CEKISCG--PPAHVENAIARGVHYQYGDMITYSCYSGYMLEGFLRSVCLENGTWT-SPPI 1393
Query: 701 CEEIRCSDP 709
C + C P
Sbjct: 1394 CRAV-CRFP 1401
Score = 152 bits (369), Expect = 6e-36
Identities = 100/331 (30%), Positives = 151/331 (45%), Gaps = 33/331 (9%)
Query: 639 PTCEYIDCGKLPTLPYGTMELLNGTTHL-GSVIQYSCTTNYRLVGPVRRTCTEEFQWSDS 697
P C C K P++ Y +E ++ GSV+ + C + L + C QW+ S
Sbjct: 2 PRCIAHFCEKPPSVSYSILESVSKAKFAAGSVVSFKCMEGFVLNTSAKIECMRGGQWNPS 61
Query: 698 --SPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEK 755
S +C +RC +P SI++ G+ G+ Y GA+V Y C K
Sbjct: 62 PMSIQCIPVRCGEP----PSIMN--------GYAS---------GSNYSFGAMVAYSCNK 100
Query: 756 GYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDE 815
G+ + GE STCE GQWS PTC V CG P ++ENG + + F YQC+
Sbjct: 101 GFYIKGEKKSTCEATGQWSSPIPTCHPVSCGEPPKVENGFLEHTTGRIFESEVR-YQCNP 159
Query: 816 NWELEGVIRRMCQENGTWSLEPPI-CKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQ 874
++ G +CQ N W E P+ C + C P I+ G + +G + +
Sbjct: 160 GYKSVGSPVFVCQANRHWHSESPLMCVPLDCGKP-PPIQNG---FMKGENFEVGSKVQFF 215
Query: 875 CERGYNLKGHQTRTCISKGQWN-GTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEY 933
C GY L G + TC G+WN + P C+P C P +EN ++V+ +T G V +
Sbjct: 216 CNEGYELVGDSSWTCQKSGKWNKKSNPKCMPAKCPEPPLLEN-QLVLKELTTEVG-VVTF 273
Query: 934 YCLSQYQRVGPFLRKCLDDGRWSGEEPSCEL 964
C + GP + KCL +W+ P C++
Sbjct: 274 SCKEGHVLQGPSVLKCLPSQQWNDSFPVCKI 304
Score = 42.3 bits (95), Expect = 0.009
Identities = 22/61 (36%), Positives = 26/61 (42%), Gaps = 3/61 (4%)
Query: 1 RCGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGT 60
RC P N + I EN G VY C+ GY L G + CT G W+ P C
Sbjct: 1224 RCETPLEFLNGKADI---ENRTTGPNVVYSCNRGYSLEGPSEAHCTENGTWSHPVPLCKP 1280
Query: 61 N 61
N
Sbjct: 1281 N 1281
Score = 37.5 bits (83), Expect = 0.26
Identities = 23/77 (29%), Positives = 29/77 (37%), Gaps = 7/77 (9%)
Query: 8 PPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTNVAFRKP 67
P + PN + + G Y+C GY+L G R C G W+ P C P
Sbjct: 878 PEDLAHGFPNGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSC-------LP 930
Query: 68 ANQSTTVRGGAAANGND 84
ST V NG D
Sbjct: 931 CRCSTPVIEYGTVNGTD 947
Score = 37.1 bits (82), Expect = 0.34
Identities = 16/58 (27%), Positives = 26/58 (44%), Gaps = 3/58 (5%)
Query: 1 RCGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
RCG P P+ + N G + Y C++G+ + G ++ C G W+ P C
Sbjct: 71 RCGEP---PSIMNGYASGSNYSFGAMVAYSCNKGFYIKGEKKSTCEATGQWSSPIPTC 125
Score = 37.1 bits (82), Expect = 0.34
Identities = 21/57 (36%), Positives = 26/57 (45%), Gaps = 3/57 (5%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C P V N +V +E I Y C+EG+ L GAR R C G W+ P C
Sbjct: 759 CSSPPVSANGQVR--GDEYTFQKEIE-YTCNEGFLLEGARSRVCLANGSWSGATPDC 812
Score = 35.9 bits (79), Expect = 0.79
Identities = 17/48 (35%), Positives = 22/48 (45%)
Query: 29 YECDEGYELFGARQRECTLRGDWTLEPPFCGTNVAFRKPANQSTTVRG 76
YECD GY L G +R C +W + P C P + + VRG
Sbjct: 725 YECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDCSSPPVSANGQVRG 772
Score = 34.7 bits (76), Expect = 1.8
Identities = 15/42 (35%), Positives = 19/42 (45%)
Query: 17 NEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
+ N + GT+ Y C+ GYEL G C G W P C
Sbjct: 597 HSSNFLYGTMVSYTCNPGYELLGNPVLICQEDGTWNGSAPSC 638
Score = 34.7 bits (76), Expect = 1.8
Identities = 21/57 (36%), Positives = 24/57 (42%), Gaps = 4/57 (7%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
CG PA NA I + G + Y C GY L G + C G WT PP C
Sbjct: 1342 CGPPAHVENA---IARGVHYQYGDMITYSCYSGYMLEGFLRSVCLENGTWT-SPPIC 1394
Score = 34.3 bits (75), Expect = 2.4
Identities = 18/57 (31%), Positives = 26/57 (45%), Gaps = 3/57 (5%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
CG + PNA +S E + + Y C GY + G+ CT +G W+ P C
Sbjct: 990 CGSLPMIPNAFIS---ETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVC 1043
Score = 34.3 bits (75), Expect = 2.4
Identities = 18/51 (35%), Positives = 25/51 (49%), Gaps = 3/51 (5%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWT 52
CG P P + V + TI +Y+C+ GYEL G R+R C W+
Sbjct: 1167 CGKPESPEHGFVV--GSKYTFESTI-IYQCEPGYELEGNRERVCQENRQWS 1214
Score = 33.5 bits (73), Expect = 4.2
Identities = 12/35 (34%), Positives = 16/35 (45%)
Query: 24 GTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
G Y C+ G+ L G C GDW ++ P C
Sbjct: 443 GQTVTYSCNRGFRLEGPSALTCLETGDWDVDAPSC 477
Score = 33.5 bits (73), Expect = 4.2
Identities = 13/30 (43%), Positives = 16/30 (53%)
Query: 29 YECDEGYELFGARQRECTLRGDWTLEPPFC 58
+ C EGY L GA + C G+W E P C
Sbjct: 841 FHCHEGYILHGAPKLTCQSDGNWDAEIPLC 870
Score = 33.1 bits (72), Expect = 5.6
Identities = 15/44 (34%), Positives = 19/44 (43%)
Query: 8 PPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDW 51
PP + EN G+ + C+EGYEL G C G W
Sbjct: 193 PPPIQNGFMKGENFEVGSKVQFFCNEGYELVGDSSWTCQKSGKW 236
>AL158158-6|CAI14071.1| 1497|Homo sapiens sushi, von Willebrand
factor type A, EGF and pentraxin domain containing 1
protein.
Length = 1497
Score = 312 bits (766), Expect = 5e-84
Identities = 187/641 (29%), Positives = 283/641 (44%), Gaps = 41/641 (6%)
Query: 349 LPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSG-APPSCK 407
+P CG P + N + G +++VGS++ + C EG+ L+GD S C+K G W+ + P C
Sbjct: 186 VPLDCGKPPPIQNGFMKGENFEVGSKVQFFCNEGYELVGDSSWTCQKSGKWNKKSNPKCM 245
Query: 408 YVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL 467
C P+ + + L + T G +SC+E L G C W+ P C
Sbjct: 246 PAKCPE-PPLLENQLVLKELTTEVGV-VTFSCKEGHVLQGPSVLKCLPSQQWNDSFPVCK 303
Query: 468 FDWCPDPPAVS-NASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKY 526
C PP +S + + GS Y+C G L G+++ C G WS P C
Sbjct: 304 IVLCTPPPLISFGVPIPSSALHFGSTVKYSCVGGFFLRGNSTTLCQPDGTWSSPLPECVP 363
Query: 527 VNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELT 586
V C P + + G Y S A +TC+P + L G +C +G W P+C+
Sbjct: 364 VECPQPEEIPNGIIDVQGLA-YLSTALYTCKPGFELVGNTTTLCGENGHWLGGKPTCKAI 422
Query: 587 SCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDC 646
C +P+ G D + T+ + C G +L G L C + G+W D+P+C I C
Sbjct: 423 ECLKPKEILNGKFSYTDLHYGQTVTYSCNRGFRLEGPSALTCLETGDWDVDAPSCNAIHC 482
Query: 647 GKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRC 706
+ G +E G++I YSC +++ G +TC EE WS S P C I C
Sbjct: 483 DSPQPIENGFVE--GADYSYGAIIIYSCFPGFQVAGHAMQTC-EESGWSSSIPTCMPIDC 539
Query: 707 SDP-----------------IVAEKSIVSV---TGNDRSHGHTLIRTSDNRDVG-----N 741
P E ++ V T + H + +T +N +
Sbjct: 540 GLPPHIDFGDCTKLKDDQGYFEQEDDMMEVPYVTPHPPYHLGAVAKTWENTKESPATHSS 599
Query: 742 TYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSN 801
+ G +V Y C GY+++G + C+++G W+G+ P+C ++C P ENG L
Sbjct: 600 NFLYGTMVSYTCNPGYELLGNPVLICQEDGTWNGSAPSCISIECDLPTAPENG--FLRFT 657
Query: 802 ATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVV 861
T G+ Y C L G R+C EN WS P C+ I+C P+ + GS +
Sbjct: 658 ETSMGSAVQYSCKPGHILAGSDLRLCLENRKWSGASPRCEAISCKKPN-PVMNGS---IK 713
Query: 862 TSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVIS 921
S + +Y+C+ GY L G + RTC W+ P+CIP+DC SP NG+ +
Sbjct: 714 GSNYTYLSTLYYECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDCSSPPVSANGQ--VR 771
Query: 922 NGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
F +EY C + G R CL +G WSG P C
Sbjct: 772 GDEYTFQKEIEYTCNEGFLLEGARSRVCLANGSWSGATPDC 812
Score = 297 bits (729), Expect = 1e-79
Identities = 180/617 (29%), Positives = 273/617 (44%), Gaps = 49/617 (7%)
Query: 350 PPTCGSPDKLLNTTILGNDYDV-GSRIVYKCPEGHMLLGDKSRHCKKDGFW-SGAPPSCK 407
P +CG P K+ N + + S + Y+C G+ +G C+ + W S +P C
Sbjct: 127 PVSCGEPPKVENGFLEHTTGRIFESEVRYQCNPGYKSVGSPVFVCQANRHWHSESPLMCV 186
Query: 408 YVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEA-PRC 466
++CG PI++G + G++ + C E + LVG+ TC G W+ ++ P+C
Sbjct: 187 PLDCGKPPPIQNGFMK--GENFEVGSKVQFFCNEGYELVGDSSWTCQKSGKWNKKSNPKC 244
Query: 467 LFDWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKY 526
+ CP+PP + N V + +++C+ GH+L G + + C W+ P CK
Sbjct: 245 MPAKCPEPPLLENQLVLKELTTEVGVVTFSCKEGHVLQGPSVLKCLPSQQWNDSFPVCKI 304
Query: 527 VNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELT 586
V C P + + + +GS +++C ++L G +C DG WS +P C
Sbjct: 305 VLCTPPPLISFGVPIPSSALHFGSTVKYSCVGGFFLRGNSTTLCQPDGTWSSPLPECVPV 364
Query: 587 SCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDC 646
CP+PE G ++ ST + C+ G +L+G +C ++G W G PTC+ I+C
Sbjct: 365 ECPQPEEIPNGIIDVQGLAYLSTALYTCKPGFELVGNTTTLCGENGHWLGGKPTCKAIEC 424
Query: 647 GKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRC 706
K + G + H G + YSC +RL GP TC E W +P C I C
Sbjct: 425 LKPKEILNGKFSYTD--LHYGQTVTYSCNRGFRLEGPSALTCLETGDWDVDAPSCNAIHC 482
Query: 707 SDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLST 766
P E V G Y GA++ Y C G++V G ++ T
Sbjct: 483 DSPQPIENGFVE---------------------GADYSYGAIIIYSCFPGFQVAGHAMQT 521
Query: 767 CEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRM 826
CE++G WS + PTC +DCG P I+ G T + Y F Q D+ E+ V
Sbjct: 522 CEESG-WSSSIPTCMPIDCGLPPHIDFGDCTKLKDDQGY----FEQEDDMMEVPYVTPHP 576
Query: 827 CQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQT 886
G + KE P+ +S G Y C GY L G+
Sbjct: 577 PYHLGAVAKTWENTKE----SPATH----------SSNFLYGTMVSYTCNPGYELLGNPV 622
Query: 887 RTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFL 946
C G WNG+ P CI I+C P ENG + + T GS+V+Y C + G L
Sbjct: 623 LICQEDGTWNGSAPSCISIECDLPTAPENGFLRFT--ETSMGSAVQYSCKPGHILAGSDL 680
Query: 947 RKCLDDGRWSGEEPSCE 963
R CL++ +WSG P CE
Sbjct: 681 RLCLENRKWSGASPRCE 697
Score = 296 bits (727), Expect = 2e-79
Identities = 186/614 (30%), Positives = 267/614 (43%), Gaps = 36/614 (5%)
Query: 352 TCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNC 411
+C P+ ++N +I G++Y S + Y+C G++L G + R C+ D W P C V+C
Sbjct: 700 SCKKPNPVMNGSIKGSNYTYLSTLYYECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDC 759
Query: 412 GGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWC 471
+G V + T Y+C E F L G R C G W G P C+ C
Sbjct: 760 SSPPVSANGQVR--GDEYTFQKEIEYTCNEGFLLEGARSRVCLANGSWSGATPDCVPVRC 817
Query: 472 PDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGT 531
PP ++N + ++ C G+IL G+ +TC G W P CK VNCG
Sbjct: 818 ATPPQLANGVTEGLDYGFMKEVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCKPVNCGP 877
Query: 532 PTIHKGSFVLING-TTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPE 590
P F NG + +G Q+ C P Y L+G C +G WS PSC C
Sbjct: 878 PEDLAHGFP--NGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCLPCRCST 935
Query: 591 PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLP 650
P V G + D+ C G KL+G + C+ DG+WS P CE+ CG LP
Sbjct: 936 P-VIEYGTVNGTDFDCGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHCEHTSCGSLP 994
Query: 651 TLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPI 710
+P + ++ +VI YSC + Y + G CTE+ WS P CE + C P
Sbjct: 995 MIPNAFIS--ETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPLSCGSP- 1051
Query: 711 VAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGES-LSTCED 769
S+ + +H TY + VK RC +GY + ++ TC+
Sbjct: 1052 ---PSVANAVATGEAH---------------TYE--SEVKLRCLEGYTMDTDTDTFTCQK 1091
Query: 770 NGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQE 829
+G+W +C C P I + + + + C E + EGV +CQ
Sbjct: 1092 DGRWFPERISCSPKKCPLPENITH--ILVHGDDFSVNRQVSVSCAEGYTFEGVNISVCQL 1149
Query: 830 NGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTC 889
+GTW EPP E P + ++ VV S + YQCE GY L+G++ R C
Sbjct: 1150 DGTW--EPPFSDESCSPVSCGKPESPEHGFVVGSKYTFESTIIYQCEPGYELEGNRERVC 1207
Query: 890 ISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKC 949
QW+G V +C C +P NGK I N +T G +V Y C Y GP C
Sbjct: 1208 QENRQWSGGVAICKETRCETPLEFLNGKADIENRTT--GPNVVYSCNRGYSLEGPSEAHC 1265
Query: 950 LDDGRWSGEEPSCE 963
++G WS P C+
Sbjct: 1266 TENGTWSHPVPLCK 1279
Score = 292 bits (717), Expect = 4e-78
Identities = 180/620 (29%), Positives = 268/620 (43%), Gaps = 50/620 (8%)
Query: 353 CGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCG 412
C P N + + +GS + Y C GH+L G R C ++ WSGA P C+ ++C
Sbjct: 643 CDLPTAPENGFLRFTETSMGSAVQYSCKPGHILAGSDLRLCLENRKWSGASPRCEAISCK 702
Query: 413 GLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCP 472
P+ +G + + T+ + Y C + L G RTC D+ WD + P C+ C
Sbjct: 703 KPNPVMNGSIK--GSNYTYLSTLYYECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDCS 760
Query: 473 DPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTP 532
PP +N V + + YTC G +L G+ S C G+WSG P C V C TP
Sbjct: 761 SPPVSANGQVRGDEYTFQKEIEYTCNEGFLLEGARSRVCLANGSWSGATPDCVPVRCATP 820
Query: 533 TIHKGSFVLINGTT---TYGSIAQ--FTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTS 587
L NG T YG + + F C Y L+GA +L C DG W +IP C+ +
Sbjct: 821 P------QLANGVTEGLDYGFMKEVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCKPVN 874
Query: 588 CPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCG 647
C PE + G+ F + I + C G+KL G + C +G WSG SP+C C
Sbjct: 875 CGPPEDLAHGFPNGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCLPCRC- 933
Query: 648 KLPTLPYGTMELLNGTT-HLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRC 706
P + YGT +NGT G + C ++L+G TC + QWS P CE C
Sbjct: 934 STPVIEYGT---VNGTDFDCGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHCEHTSC 990
Query: 707 SDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLST 766
+ + +S T + + + ++ Y C GY + G S
Sbjct: 991 GSLPMIPNAFISETSSWKEN---------------------VITYSCRSGYVIQGSSDLI 1029
Query: 767 CEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELE-GVIRR 825
C + G WS P C+ + CG+P + N T A Y + +C E + ++
Sbjct: 1030 CTEKGVWSQPYPVCEPLSCGSPPSVANAVAT--GEAHTYESEVKLRCLEGYTMDTDTDTF 1087
Query: 826 MCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQ 885
CQ++G W E C CP P + + +LV S+ + C GY +G
Sbjct: 1088 TCQKDGRWFPERISCSPKKCPLP----ENITHILVHGDDFSVNRQVSVSCAEGYTFEGVN 1143
Query: 886 TRTCISKGQWNG--TVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVG 943
C G W + C P+ C P + E+G +V S + F S++ Y C Y+ G
Sbjct: 1144 ISVCQLDGTWEPPFSDESCSPVSCGKPESPEHGFVVGSKYT--FESTIIYQCEPGYELEG 1201
Query: 944 PFLRKCLDDGRWSGEEPSCE 963
R C ++ +WSG C+
Sbjct: 1202 NRERVCQENRQWSGGVAICK 1221
Score = 291 bits (714), Expect = 9e-78
Identities = 176/586 (30%), Positives = 255/586 (43%), Gaps = 38/586 (6%)
Query: 372 GSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRTTH 431
G+ + Y C G+ LLG+ C++DG W+G+ PSC + C T E+G + + T+
Sbjct: 604 GTMVSYTCNPGYELLGNPVLICQEDGTWNGSAPSCISIECDLPTAPENGFLRFTE--TSM 661
Query: 432 GARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGS 491
G+ YSC+ L G+ R C + W G +PRC C P V N S+ + + S
Sbjct: 662 GSAVQYSCKPGHILAGSDLRLCLENRKWSGASPRCEAISCKKPNPVMNGSIKGSNYTYLS 721
Query: 492 LASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTIHKGSFVLINGTTTYGSI 551
Y C+ G++L+G+ TC W P C V+C +P + V T+
Sbjct: 722 TLYYECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDCSSPPVSANGQVR-GDEYTFQKE 780
Query: 552 AQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFDYYVHSTIN 611
++TC + L GA VC +G WS P C C P + G E DY +
Sbjct: 781 IEYTCNEGFLLEGARSRVCLANGSWSGATPDCVPVRCATPPQLANGVTEGLDYGFMKEVT 840
Query: 612 FHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHL-GSVI 670
FHC G+ L G P L CQ DG W + P C+ ++CG L +G NG + + G I
Sbjct: 841 FHCHEGYILHGAPKLTCQSDGNWDAEIPLCKPVNCGPPEDLAHG---FPNGFSFIHGGHI 897
Query: 671 QYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTL 730
QY C Y+L G R C WS SSP C RCS P++ +V G D
Sbjct: 898 QYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCLPCRCSTPVI---EYGTVNGTD------- 947
Query: 731 IRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGR 790
D G RI +C KG+K++G S TCE +GQWS P C++ CG+
Sbjct: 948 ------FDCGKAARI------QCFKGFKLLGLSEITCEADGQWSSGFPHCEHTSCGSLPM 995
Query: 791 IENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSA 850
I N ++ +++ Y C + ++G +C E G WS P+C+ ++C P +
Sbjct: 996 IPNAFIS--ETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPLSCGSPPS 1053
Query: 851 QIKAGSGLLVVTSTLSIGGEAHYQCERGYNL-KGHQTRTCISKGQWNGTVPVCIPIDCRS 909
A + + E +C GY + T TC G+W C P C
Sbjct: 1054 VANA----VATGEAHTYESEVKLRCLEGYTMDTDTDTFTCQKDGRWFPERISCSPKKCPL 1109
Query: 910 PGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRW 955
P NI + I++ V C Y G + C DG W
Sbjct: 1110 PENITH--ILVHGDDFSVNRQVSVSCAEGYTFEGVNISVCQLDGTW 1153
Score = 286 bits (701), Expect = 3e-76
Identities = 183/621 (29%), Positives = 267/621 (42%), Gaps = 43/621 (6%)
Query: 349 LPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKY 408
+P C SP N + G++Y I Y C EG +L G +SR C +G WSGA P C
Sbjct: 755 IPVDCSSPPVSANGQVRGDEYTFQKEIEYTCNEGFLLEGARSRVCLANGSWSGATPDCVP 814
Query: 409 VNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLF 468
V C + +G +D + C E + L G P+ TC +G WD E P C
Sbjct: 815 VRCATPPQLANGVTEGLDYGFMK--EVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCKP 872
Query: 469 DWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVN 528
C P +++ G Y C G+ L G++S C G+WSG PSC
Sbjct: 873 VNCGPPEDLAHGFPNGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCLPCR 932
Query: 529 CGTPTIHKGSFVLINGTT-TYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTS 587
C TP I G+ +NGT G A+ C + L G E+ C DG+WS P CE TS
Sbjct: 933 CSTPVIEYGT---VNGTDFDCGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHCEHTS 989
Query: 588 CPE-PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDC 646
C P +P+ ++ + + I + C +G+ + G +L+C + G WS P CE + C
Sbjct: 990 CGSLPMIPN-AFISETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPLSC 1048
Query: 647 GKLPTLPYGTMELLNGTTH-LGSVIQYSCTTNYRL-VGPVRRTCTEEFQWSDSSPRCEEI 704
G P++ + G H S ++ C Y + TC ++ +W C
Sbjct: 1049 GSPPSV---ANAVATGEAHTYESEVKLRCLEGYTMDTDTDTFTCQKDGRWFPERISCSPK 1105
Query: 705 RCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESL 764
+C P ++T H L+ G+ + + V C +GY G ++
Sbjct: 1106 KCPLP-------ENIT-------HILVH-------GDDFSVNRQVSVSCAEGYTFEGVNI 1144
Query: 765 STCEDNGQWSG--TTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGV 822
S C+ +G W + +C V CG P E+G V + S TF +T YQC+ +ELEG
Sbjct: 1145 SVCQLDGTWEPPFSDESCSPVSCGKPESPEHGFV-VGSKYTF-ESTIIYQCEPGYELEGN 1202
Query: 823 IRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLK 882
R+CQEN WS ICKE C P + + + + G Y C RGY+L+
Sbjct: 1203 RERVCQENRQWSGGVAICKETRCETPLEFLNGKADI----ENRTTGPNVVYSCNRGYSLE 1258
Query: 883 GHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRV 942
G C G W+ VP+C P C P I + +S +V C +
Sbjct: 1259 GPSEAHCTENGTWSHPVPLCKPNPCPVPFVIPENAL-LSEKEFYVDQNVSIKCREGFLLQ 1317
Query: 943 GPFLRKCLDDGRWSGEEPSCE 963
G + C D W+ CE
Sbjct: 1318 GHGIITCNPDETWTQTSAKCE 1338
Score = 274 bits (671), Expect = 1e-72
Identities = 176/621 (28%), Positives = 253/621 (40%), Gaps = 46/621 (7%)
Query: 349 LPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKY 408
+P C +P +L N G DY + + C EG++L G C+ DG W P CK
Sbjct: 813 VPVRCATPPQLANGVTEGLDYGFMKEVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCKP 872
Query: 409 VNCGGLTPIEDGDVALIDNRT-THGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL 467
VNCG P ED + + HG Y C + L GN R C G W G +P CL
Sbjct: 873 VNCG---PPEDLAHGFPNGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCL 929
Query: 468 FDWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYV 527
C P + +V G A C G L G + +TC G WS P C++
Sbjct: 930 PCRC-STPVIEYGTVNGTDFDCGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHCEHT 988
Query: 528 NCGTPTIHKGSFVLINGTTTYG-SIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELT 586
+CG+ + +F I+ T+++ ++ ++C Y + G+ +L+C G WS P CE
Sbjct: 989 SCGSLPMIPNAF--ISETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPL 1046
Query: 587 SCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPN-LVCQQDGEWSGDSPTCEYID 645
SC P + + S + C G+ + + + CQ+DG W + +C
Sbjct: 1047 SCGSPPSVANAVATGEAHTYESEVKLRCLEGYTMDTDTDTFTCQKDGRWFPERISCSPKK 1106
Query: 646 CGKLPTLPYGTMELLNGTTH-LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSD--SSPRCE 702
C P T L++G + + SC Y G C + W S C
Sbjct: 1107 C---PLPENITHILVHGDDFSVNRQVSVSCAEGYTFEGVNISVCQLDGTWEPPFSDESCS 1163
Query: 703 EIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGE 762
+ C P E HG VG+ Y + + Y+CE GY++ G
Sbjct: 1164 PVSCGKPESPE------------HGFV---------VGSKYTFESTIIYQCEPGYELEGN 1202
Query: 763 SLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGV 822
C++N QWSG C+ C P NGK + + T G Y C+ + LEG
Sbjct: 1203 RERVCQENRQWSGGVAICKETRCETPLEFLNGKADIENRTT--GPNVVYSCNRGYSLEGP 1260
Query: 823 IRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLK 882
C ENGTWS P+CK CP P L+ + +C G+ L+
Sbjct: 1261 SEAHCTENGTWSHPVPLCKPNPCPVP---FVIPENALLSEKEFYVDQNVSIKCREGFLLQ 1317
Query: 883 GHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRV 942
GH TC W T C I C P ++EN + +G + Y C S Y
Sbjct: 1318 GHGIITCNPDETWTQTSAKCEKISCGPPAHVENA--IARGVHYQYGDMITYSCYSGYMLE 1375
Query: 943 GPFLRK-CLDDGRWSGEEPSC 962
G FLR CL++G W+ P C
Sbjct: 1376 G-FLRSVCLENGTWT-SPPIC 1394
Score = 273 bits (670), Expect = 2e-72
Identities = 159/507 (31%), Positives = 244/507 (48%), Gaps = 39/507 (7%)
Query: 464 PRCLFDWCPDPPAVSNA---SVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGV 520
PRC+ +C PP+VS + SV+ AGS+ S+ C G +L+ S + C GG W+
Sbjct: 2 PRCIAHFCEKPPSVSYSILESVSKAKFAAGSVVSFKCMEGFVLNTSAKIECMRGGQWNPS 61
Query: 521 PPS--CKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSY 578
P S C V CG P + ++G++ ++C +++ G ++ C G+WS
Sbjct: 62 PMSIQCIPVRCGEPPSIMNGYA-SGSNYSFGAMVAYSCNKGFYIKGEKKSTCEATGQWSS 120
Query: 579 DIPSCELTSCPEPEVPSGGYME-AFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGD 637
IP+C SC EP G++E S + + C G+K +G P VCQ + W +
Sbjct: 121 PIPTCHPVSCGEPPKVENGFLEHTTGRIFESEVRYQCNPGYKSVGSPVFVCQANRHWHSE 180
Query: 638 SP-TCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWS- 695
SP C +DCGK P + G M+ N +GS +Q+ C Y LVG TC + +W+
Sbjct: 181 SPLMCVPLDCGKPPPIQNGFMKGEN--FEVGSKVQFFCNEGYELVGDSSWTCQKSGKWNK 238
Query: 696 DSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEK 755
S+P+C +C +P + E +V +++ T +G +V + C++
Sbjct: 239 KSNPKCMPAKCPEPPLLENQLVL------------------KEL--TTEVG-VVTFSCKE 277
Query: 756 GYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDE 815
G+ + G S+ C + QW+ + P C+ V C P I G V +PS+A +G+T Y C
Sbjct: 278 GHVLQGPSVLKCLPSQQWNDSFPVCKIVLCTPPPLISFG-VPIPSSALHFGSTVKYSCVG 336
Query: 816 NWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQC 875
+ L G +CQ +GTWS P C + CP P +I G ++ L+ A Y C
Sbjct: 337 GFFLRGNSTTLCQPDGTWSSPLPECVPVECPQPE-EIPNG---IIDVQGLAYLSTALYTC 392
Query: 876 ERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYC 935
+ G+ L G+ T C G W G P C I+C P I NGK S +G +V Y C
Sbjct: 393 KPGFELVGNTTTLCGENGHWLGGKPTCKAIECLKPKEILNGK--FSYTDLHYGQTVTYSC 450
Query: 936 LSQYQRVGPFLRKCLDDGRWSGEEPSC 962
++ GP CL+ G W + PSC
Sbjct: 451 NRGFRLEGPSALTCLETGDWDVDAPSC 477
Score = 266 bits (651), Expect = 4e-70
Identities = 165/537 (30%), Positives = 232/537 (43%), Gaps = 42/537 (7%)
Query: 431 HGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAG 490
+G Y+C + L+GNP C ++G W+G AP C+ C P A N + G
Sbjct: 603 YGTMVSYTCNPGYELLGNPVLICQEDGTWNGSAPSCISIECDLPTAPENGFLRFTETSMG 662
Query: 491 SLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPT-IHKGSFVLINGTT-TY 548
S Y+C+ GHIL+GS C WSG P C+ ++C P + GS I G+ TY
Sbjct: 663 SAVQYSCKPGHILAGSDLRLCLENRKWSGASPRCEAISCKKPNPVMNGS---IKGSNYTY 719
Query: 549 GSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFDYYVHS 608
S + C+P Y LNG E C D W D P C C P V + G + +Y
Sbjct: 720 LSTLYYECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDCSSPPVSANGQVRGDEYTFQK 779
Query: 609 TINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGS 668
I + C G L G + VC +G WSG +P C + C P L G E L+
Sbjct: 780 EIEYTCNEGFLLEGARSRVCLANGSWSGATPDCVPVRCATPPQLANGVTEGLD--YGFMK 837
Query: 669 VIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGH 728
+ + C Y L G + TC + W P C+ + C P D +HG
Sbjct: 838 EVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCKPVNCGPP------------EDLAHGF 885
Query: 729 TLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNP 788
G ++ G ++Y+C GYK+ G S C NG WSG++P+C C P
Sbjct: 886 ---------PNGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCLPCRCSTP 936
Query: 789 GRIENGKVTLPSNATFY--GATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCP 846
IE G V N T + G A QC + ++L G+ C+ +G WS P C+ +C
Sbjct: 937 -VIEYGTV----NGTDFDCGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHCEHTSC- 990
Query: 847 DPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPID 906
+ + + TS+ Y C GY ++G C KG W+ PVC P+
Sbjct: 991 --GSLPMIPNAFISETSSWK-ENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPLS 1047
Query: 907 CRSPGNIENGKIVISNGSTLFGSSVEYYCLSQY-QRVGPFLRKCLDDGRWSGEEPSC 962
C SP ++ N V + + + S V+ CL Y C DGRW E SC
Sbjct: 1048 CGSPPSVANA--VATGEAHTYESEVKLRCLEGYTMDTDTDTFTCQKDGRWFPERISC 1102
Score = 262 bits (641), Expect = 6e-69
Identities = 163/553 (29%), Positives = 232/553 (41%), Gaps = 37/553 (6%)
Query: 369 YDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPS--CKYVNCGGLTPIEDGDVALID 426
+ GS + +KC EG +L C + G W+ +P S C V CG I +G +
Sbjct: 28 FAAGSVVSFKCMEGFVLNTSAKIECMRGGQWNPSPMSIQCIPVRCGEPPSIMNGYAS--G 85
Query: 427 NRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVT-VN 485
+ + GA YSC + F + G + TC G W P C C +PP V N +
Sbjct: 86 SNYSFGAMVAYSCNKGFYIKGEKKSTCEATGQWSSPIPTCHPVSCGEPPKVENGFLEHTT 145
Query: 486 GHKAGSLASYTCENGHILSGSTSVTCTLGGAW-SGVPPSCKYVNCGTPTIHKGSFVLING 544
G S Y C G+ GS C W S P C ++CG P + F +
Sbjct: 146 GRIFESEVRYQCNPGYKSVGSPVFVCQANRHWHSESPLMCVPLDCGKPPPIQNGF-MKGE 204
Query: 545 TTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWS-YDIPSCELTSCPEPEVPSGGYMEAFD 603
GS QF C Y L G C + GKW+ P C CPEP + +
Sbjct: 205 NFEVGSKVQFFCNEGYELVGDSSWTCQKSGKWNKKSNPKCMPAKCPEPPLLENQLVLKEL 264
Query: 604 YYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGT 663
+ F C+ GH L G L C +W+ P C+ + C P + +G + + +
Sbjct: 265 TTEVGVVTFSCKEGHVLQGPSVLKCLPSQQWNDSFPVCKIVLCTPPPLISFG-VPIPSSA 323
Query: 664 THLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGND 723
H GS ++YSC + L G C + WS P C + C P I+ V
Sbjct: 324 LHFGSTVKYSCVGGFFLRGNSTTLCQPDGTWSSPLPECVPVECPQPEEIPNGIIDVQ--- 380
Query: 724 RSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYV 783
G Y AL Y C+ G++++G + + C +NG W G PTC+ +
Sbjct: 381 ----------------GLAYLSTAL--YTCKPGFELVGNTTTLCGENGHWLGGKPTCKAI 422
Query: 784 DCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEI 843
+C P I NGK + YG T Y C+ + LEG C E G W ++ P C I
Sbjct: 423 ECLKPKEILNGKFSYTD--LHYGQTVTYSCNRGFRLEGPSALTCLETGDWDVDAPSCNAI 480
Query: 844 TCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCI 903
C P I+ G V + S G Y C G+ + GH +TC G W+ ++P C+
Sbjct: 481 HCDSPQ-PIENG---FVEGADYSYGAIIIYSCFPGFQVAGHAMQTCEESG-WSSSIPTCM 535
Query: 904 PIDCRSPGNIENG 916
PIDC P +I+ G
Sbjct: 536 PIDCGLPPHIDFG 548
Score = 248 bits (607), Expect = 8e-65
Identities = 145/505 (28%), Positives = 219/505 (43%), Gaps = 31/505 (6%)
Query: 347 QYLPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSC 406
Q +P CG P ++N G++Y G+ + Y C +G + G+K C+ G WS P+C
Sbjct: 66 QCIPVRCGEPPSIMNGYASGSNYSFGAMVAYSCNKGFYIKGEKKSTCEATGQWSSPIPTC 125
Query: 407 KYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAP-R 465
V+CG +E+G + R + Y C + VG+P C W E+P
Sbjct: 126 HPVSCGEPPKVENGFLEHTTGRIFE-SEVRYQCNPGYKSVGSPVFVCQANRHWHSESPLM 184
Query: 466 CLFDWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVP-PSC 524
C+ C PP + N + + GS + C G+ L G +S TC G W+ P C
Sbjct: 185 CVPLDCGKPPPIQNGFMKGENFEVGSKVQFFCNEGYELVGDSSWTCQKSGKWNKKSNPKC 244
Query: 525 KYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCE 584
C P + + VL TT G + F+C+ + L G L C +W+ P C+
Sbjct: 245 MPAKCPEPPLLENQLVLKELTTEVG-VVTFSCKEGHVLQGPSVLKCLPSQQWNDSFPVCK 303
Query: 585 LTSC-PEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEY 643
+ C P P + G + + + ST+ + C G L G +CQ DG WS P C
Sbjct: 304 IVLCTPPPLISFGVPIPSSALHFGSTVKYSCVGGFFLRGNSTTLCQPDGTWSSPLPECVP 363
Query: 644 IDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEE 703
++C + +P G ++ + G +L + + Y+C + LVG C E W P C+
Sbjct: 364 VECPQPEEIPNGIID-VQGLAYLSTAL-YTCKPGFELVGNTTTLCGENGHWLGGKPTCKA 421
Query: 704 IRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGES 763
I C P S T D +G T V Y C +G+++ G S
Sbjct: 422 IECLKPKEILNGKFSYT--DLHYGQT-------------------VTYSCNRGFRLEGPS 460
Query: 764 LSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVI 823
TC + G W P+C + C +P IENG V + YGA Y C +++ G
Sbjct: 461 ALTCLETGDWDVDAPSCNAIHCDSPQPIENGFVEGADYS--YGAIIIYSCFPGFQVAGHA 518
Query: 824 RRMCQENGTWSLEPPICKEITCPDP 848
+ C+E+G WS P C I C P
Sbjct: 519 MQTCEESG-WSSSIPTCMPIDCGLP 542
Score = 165 bits (402), Expect = 6e-40
Identities = 124/483 (25%), Positives = 191/483 (39%), Gaps = 49/483 (10%)
Query: 352 TCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNC 411
+CGS + N I + I Y C G+++ G C + G WS P C+ ++C
Sbjct: 989 SCGSLPMIPNAFISETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPLSC 1048
Query: 412 GGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPER-TCGDEGIWDGEAPRCLFDW 470
G +P + T+ + C E +T+ + + TC +G W E C
Sbjct: 1049 G--SPPSVANAVATGEAHTYESEVKLRCLEGYTMDTDTDTFTCQKDGRWFPERISCSPKK 1106
Query: 471 CPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPP----SCKY 526
CP P +++ V + S +C G+ G C L G W PP SC
Sbjct: 1107 CPLPENITHILVHGDDFSVNRQVSVSCAEGYTFEGVNISVCQLDGTWE--PPFSDESCSP 1164
Query: 527 VNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELT 586
V+CG P + FV + T+ S + CEP Y L G E VC + +WS + C+ T
Sbjct: 1165 VSCGKPESPEHGFV-VGSKYTFESTIIYQCEPGYELEGNRERVCQENRQWSGGVAICKET 1223
Query: 587 SCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDC 646
C P G + + + + C G+ L G C ++G WS P C+ C
Sbjct: 1224 RCETPLEFLNGKADIENRTTGPNVVYSCNRGYSLEGPSEAHCTENGTWSHPVPLCKPNPC 1283
Query: 647 GKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRC 706
+P + L ++ + C + L G TC + W+ +S +CE+I C
Sbjct: 1284 PVPFVIPENAL-LSEKEFYVDQNVSIKCREGFLLQGHGIITCNPDETWTQTSAKCEKISC 1342
Query: 707 SDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLST 766
P E +I G Y+ G ++ Y C GY + G S
Sbjct: 1343 GPPAHVENAIAR---------------------GVHYQYGDMITYSCYSGYMLEGFLRSV 1381
Query: 767 CEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRM 826
C +NG W+ + P C+ V C P +NG + NA C E W + R+
Sbjct: 1382 CLENGTWT-SPPICRAV-CRFP--CQNGGICQRPNAC--------SCPEGW-----MGRL 1424
Query: 827 CQE 829
C+E
Sbjct: 1425 CEE 1427
Score = 162 bits (394), Expect = 5e-39
Identities = 106/390 (27%), Positives = 167/390 (42%), Gaps = 36/390 (9%)
Query: 580 IPSCELTSCPEPEVPSGGYMEAFD---YYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSG 636
+P C C +P S +E+ + S ++F C G L + C + G+W+
Sbjct: 1 MPRCIAHFCEKPPSVSYSILESVSKAKFAAGSVVSFKCMEGFVLNTSAKIECMRGGQWNP 60
Query: 637 D--SPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQW 694
S C + CG+ P++ G N + G+++ YSC + + G + TC QW
Sbjct: 61 SPMSIQCIPVRCGEPPSIMNGYASGSNYS--FGAMVAYSCNKGFYIKGEKKSTCEATGQW 118
Query: 695 SDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCE 754
S P C + C +P E + HT R ++ V+Y+C
Sbjct: 119 SSPIPTCHPVSCGEPPKVENGFLE---------HTTGRIFESE-----------VRYQCN 158
Query: 755 KGYKVIGESLSTCEDNGQWSGTTP-TCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQC 813
GYK +G + C+ N W +P C +DCG P I+NG + G+ + C
Sbjct: 159 PGYKSVGSPVFVCQANRHWHSESPLMCVPLDCGKPPPIQNG--FMKGENFEVGSKVQFFC 216
Query: 814 DENWELEGVIRRMCQENGTWSLEP-PICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAH 872
+E +EL G CQ++G W+ + P C CP+P LV+ + G
Sbjct: 217 NEGYELVGDSSWTCQKSGKWNKKSNPKCMPAKCPEPPLL----ENQLVLKELTTEVGVVT 272
Query: 873 YQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVE 932
+ C+ G+ L+G C+ QWN + PVC + C P I G + I + + FGS+V+
Sbjct: 273 FSCKEGHVLQGPSVLKCLPSQQWNDSFPVCKIVLCTPPPLISFG-VPIPSSALHFGSTVK 331
Query: 933 YYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
Y C+ + G C DG WS P C
Sbjct: 332 YSCVGGFFLRGNSTTLCQPDGTWSSPLPEC 361
Score = 153 bits (371), Expect = 3e-36
Identities = 103/369 (27%), Positives = 145/369 (39%), Gaps = 13/369 (3%)
Query: 345 ICQYLPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRH-CKKDGFWSGAP 403
+C+ P +CGSP + N G + S + +C EG+ + D C+KDG W
Sbjct: 1042 VCE--PLSCGSPPSVANAVATGEAHTYESEVKLRCLEGYTMDTDTDTFTCQKDGRWFPER 1099
Query: 404 PSCKYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDG-- 461
SC C P + + + + + SC E +T G C +G W+
Sbjct: 1100 ISCSPKKCP--LPENITHILVHGDDFSVNRQVSVSCAEGYTFEGVNISVCQLDGTWEPPF 1157
Query: 462 EAPRCLFDWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVP 521
C C P + + V + + S Y CE G+ L G+ C WSG
Sbjct: 1158 SDESCSPVSCGKPESPEHGFVVGSKYTFESTIIYQCEPGYELEGNRERVCQENRQWSGGV 1217
Query: 522 PSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIP 581
CK C TP I TT G ++C Y L G E C +G WS+ +P
Sbjct: 1218 AICKETRCETPLEFLNGKADIENRTT-GPNVVYSCNRGYSLEGPSEAHCTENGTWSHPVP 1276
Query: 582 SCELTSCPEPEV-PSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPT 640
C+ CP P V P + ++YV ++ C G L G + C D W+ S
Sbjct: 1277 LCKPNPCPVPFVIPENALLSEKEFYVDQNVSIKCREGFLLQGHGIITCNPDETWTQTSAK 1336
Query: 641 CEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPR 700
CE I CG P G +I YSC + Y L G +R C E W+ S P
Sbjct: 1337 CEKISCG--PPAHVENAIARGVHYQYGDMITYSCYSGYMLEGFLRSVCLENGTWT-SPPI 1393
Query: 701 CEEIRCSDP 709
C + C P
Sbjct: 1394 CRAV-CRFP 1401
Score = 152 bits (369), Expect = 6e-36
Identities = 100/331 (30%), Positives = 151/331 (45%), Gaps = 33/331 (9%)
Query: 639 PTCEYIDCGKLPTLPYGTMELLNGTTHL-GSVIQYSCTTNYRLVGPVRRTCTEEFQWSDS 697
P C C K P++ Y +E ++ GSV+ + C + L + C QW+ S
Sbjct: 2 PRCIAHFCEKPPSVSYSILESVSKAKFAAGSVVSFKCMEGFVLNTSAKIECMRGGQWNPS 61
Query: 698 --SPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEK 755
S +C +RC +P SI++ G+ G+ Y GA+V Y C K
Sbjct: 62 PMSIQCIPVRCGEP----PSIMN--------GYAS---------GSNYSFGAMVAYSCNK 100
Query: 756 GYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDE 815
G+ + GE STCE GQWS PTC V CG P ++ENG + + F YQC+
Sbjct: 101 GFYIKGEKKSTCEATGQWSSPIPTCHPVSCGEPPKVENGFLEHTTGRIFESEVR-YQCNP 159
Query: 816 NWELEGVIRRMCQENGTWSLEPPI-CKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQ 874
++ G +CQ N W E P+ C + C P I+ G + +G + +
Sbjct: 160 GYKSVGSPVFVCQANRHWHSESPLMCVPLDCGKP-PPIQNG---FMKGENFEVGSKVQFF 215
Query: 875 CERGYNLKGHQTRTCISKGQWN-GTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEY 933
C GY L G + TC G+WN + P C+P C P +EN ++V+ +T G V +
Sbjct: 216 CNEGYELVGDSSWTCQKSGKWNKKSNPKCMPAKCPEPPLLEN-QLVLKELTTEVG-VVTF 273
Query: 934 YCLSQYQRVGPFLRKCLDDGRWSGEEPSCEL 964
C + GP + KCL +W+ P C++
Sbjct: 274 SCKEGHVLQGPSVLKCLPSQQWNDSFPVCKI 304
Score = 42.3 bits (95), Expect = 0.009
Identities = 22/61 (36%), Positives = 26/61 (42%), Gaps = 3/61 (4%)
Query: 1 RCGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGT 60
RC P N + I EN G VY C+ GY L G + CT G W+ P C
Sbjct: 1224 RCETPLEFLNGKADI---ENRTTGPNVVYSCNRGYSLEGPSEAHCTENGTWSHPVPLCKP 1280
Query: 61 N 61
N
Sbjct: 1281 N 1281
Score = 37.5 bits (83), Expect = 0.26
Identities = 23/77 (29%), Positives = 29/77 (37%), Gaps = 7/77 (9%)
Query: 8 PPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTNVAFRKP 67
P + PN + + G Y+C GY+L G R C G W+ P C P
Sbjct: 878 PEDLAHGFPNGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSC-------LP 930
Query: 68 ANQSTTVRGGAAANGND 84
ST V NG D
Sbjct: 931 CRCSTPVIEYGTVNGTD 947
Score = 37.1 bits (82), Expect = 0.34
Identities = 16/58 (27%), Positives = 26/58 (44%), Gaps = 3/58 (5%)
Query: 1 RCGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
RCG P P+ + N G + Y C++G+ + G ++ C G W+ P C
Sbjct: 71 RCGEP---PSIMNGYASGSNYSFGAMVAYSCNKGFYIKGEKKSTCEATGQWSSPIPTC 125
Score = 37.1 bits (82), Expect = 0.34
Identities = 21/57 (36%), Positives = 26/57 (45%), Gaps = 3/57 (5%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C P V N +V +E I Y C+EG+ L GAR R C G W+ P C
Sbjct: 759 CSSPPVSANGQVR--GDEYTFQKEIE-YTCNEGFLLEGARSRVCLANGSWSGATPDC 812
Score = 35.9 bits (79), Expect = 0.79
Identities = 17/48 (35%), Positives = 22/48 (45%)
Query: 29 YECDEGYELFGARQRECTLRGDWTLEPPFCGTNVAFRKPANQSTTVRG 76
YECD GY L G +R C +W + P C P + + VRG
Sbjct: 725 YECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDCSSPPVSANGQVRG 772
Score = 34.7 bits (76), Expect = 1.8
Identities = 15/42 (35%), Positives = 19/42 (45%)
Query: 17 NEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
+ N + GT+ Y C+ GYEL G C G W P C
Sbjct: 597 HSSNFLYGTMVSYTCNPGYELLGNPVLICQEDGTWNGSAPSC 638
Score = 34.7 bits (76), Expect = 1.8
Identities = 21/57 (36%), Positives = 24/57 (42%), Gaps = 4/57 (7%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
CG PA NA I + G + Y C GY L G + C G WT PP C
Sbjct: 1342 CGPPAHVENA---IARGVHYQYGDMITYSCYSGYMLEGFLRSVCLENGTWT-SPPIC 1394
Score = 34.3 bits (75), Expect = 2.4
Identities = 18/57 (31%), Positives = 26/57 (45%), Gaps = 3/57 (5%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
CG + PNA +S E + + Y C GY + G+ CT +G W+ P C
Sbjct: 990 CGSLPMIPNAFIS---ETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVC 1043
Score = 34.3 bits (75), Expect = 2.4
Identities = 18/51 (35%), Positives = 25/51 (49%), Gaps = 3/51 (5%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWT 52
CG P P + V + TI +Y+C+ GYEL G R+R C W+
Sbjct: 1167 CGKPESPEHGFVV--GSKYTFESTI-IYQCEPGYELEGNRERVCQENRQWS 1214
Score = 33.5 bits (73), Expect = 4.2
Identities = 12/35 (34%), Positives = 16/35 (45%)
Query: 24 GTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
G Y C+ G+ L G C GDW ++ P C
Sbjct: 443 GQTVTYSCNRGFRLEGPSALTCLETGDWDVDAPSC 477
Score = 33.5 bits (73), Expect = 4.2
Identities = 13/30 (43%), Positives = 16/30 (53%)
Query: 29 YECDEGYELFGARQRECTLRGDWTLEPPFC 58
+ C EGY L GA + C G+W E P C
Sbjct: 841 FHCHEGYILHGAPKLTCQSDGNWDAEIPLC 870
Score = 33.1 bits (72), Expect = 5.6
Identities = 15/44 (34%), Positives = 19/44 (43%)
Query: 8 PPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDW 51
PP + EN G+ + C+EGYEL G C G W
Sbjct: 193 PPPIQNGFMKGENFEVGSKVQFFCNEGYELVGDSSWTCQKSGKW 236
>AY210418-1|AAO34701.1| 3487|Homo sapiens CUB and sushi multiple
domains 2 protein.
Length = 3487
Score = 312 bits (765), Expect = 6e-84
Identities = 195/634 (30%), Positives = 292/634 (46%), Gaps = 48/634 (7%)
Query: 347 QYLPPTCGSPDKLLNTTILGN-DYDVGSRIVYKCPEGHMLLGDKSRHCKK--DGF--WSG 401
+Y P C P L+ ILG G I + C G+ L+G C + G+ WS
Sbjct: 2462 RYSAPYCSLPRAPLHGFILGQTSTQPGGSIHFGCNAGYRLVGHSMAICTRHPQGYHLWSE 2521
Query: 402 APPSCKYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERT--CGDEGIW 459
A P C+ ++CG ++G V T G +A+YSC E + L E T C D G+W
Sbjct: 2522 AIPLCQALSCGLPEAPKNGMV--FGKEYTVGTKAMYSCSEGYHLQAGAEATAECLDTGLW 2579
Query: 460 DGE--APRCLFDWCPDPPAVSNAS-----VTVNGHKAGSLASYTCENGHILSGSTSVTCT 512
P+C+ CPD ++S + ++ + C+ G+ +G + C
Sbjct: 2580 SNRNVPPQCVPVTCPDVSSISVEHGRWRLIFETQYQFQAQLMLICDPGYYYTGQRVIRCQ 2639
Query: 513 LGGAWS--GVPPSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVC 570
G WS P+C+ ++CG I I + YG+ A F+C Y L G+ C
Sbjct: 2640 ANGKWSLGDSTPTCRIISCGELPIPPNGH-RIGTLSVYGATAIFSCNSGYTLVGSRVREC 2698
Query: 571 NRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQ 630
+G WS C C PE G++ +Y ++ + C AG +LIG +CQQ
Sbjct: 2699 MANGLWSGSEVRCLAGHCGTPEPIVNGHINGENYSYRGSVVYQCNAGFRLIGMSVRICQQ 2758
Query: 631 DGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTE 690
D WSG +P C + CG + P+ M + +G+V++YSC LVG R C
Sbjct: 2759 DHHWSGKTPFCVLVSCGHPGSPPHSQMS--GDSYTVGAVVRYSCIGKRTLVGNSTRMCGL 2816
Query: 691 EFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVK 750
+ W+ S P C + V V G+ H + +G+++ G +++
Sbjct: 2817 DGHWTGSLPHC-----------SGTSVGVCGDPGIPAHGI-------RLGDSFDPGTVMR 2858
Query: 751 YRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAF 810
+ CE G+ + G S TC+ NG WSG+ P C + CGNPG N +V S+ + ++
Sbjct: 2859 FSCEAGHVLRGSSERTCQANGSWSGSQPECGVISCGNPGTPSNARVVF-SDGLVFSSSIV 2917
Query: 811 YQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGE 870
Y+C E + G++ R C NGTW+ P C I C DP I A L + +
Sbjct: 2918 YECREGYYATGLLSRHCSVNGTWTGSDPECLVINCGDPG--IPANG--LRLGNDFRYNKT 2973
Query: 871 AHYQCERGYNLKGHQTR--TCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFG 928
YQC GY ++ H+ +C WNGT PVC + C+ P I NGK+V S+ ++G
Sbjct: 2974 VTYQCVPGYMMESHRVSVLSCTKDRTWNGTKPVCKALMCKPPPLIPNGKVVGSD--FMWG 3031
Query: 929 SSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
SSV Y CL YQ P + C +G W+GE P C
Sbjct: 3032 SSVTYACLEGYQLSLPAVFTCEGNGSWTGELPQC 3065
Score = 293 bits (720), Expect = 2e-78
Identities = 168/562 (29%), Positives = 255/562 (45%), Gaps = 38/562 (6%)
Query: 353 CGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCG 412
CG+P+ ++N I G +Y +VY+C G L+G R C++D WSG P C V+CG
Sbjct: 2716 CGTPEPIVNGHINGENYSYRGSVVYQCNAGFRLIGMSVRICQQDHHWSGKTPFCVLVSCG 2775
Query: 413 GLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL---FD 469
P + + T GA YSC TLVGN R CG +G W G P C
Sbjct: 2776 H--PGSPPHSQMSGDSYTVGAVVRYSCIGKRTLVGNSTRMCGLDGHWTGSLPHCSGTSVG 2833
Query: 470 WCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNC 529
C DP ++ + G++ ++CE GH+L GS+ TC G+WSG P C ++C
Sbjct: 2834 VCGDPGIPAHGIRLGDSFDPGTVMRFSCEAGHVLRGSSERTCQANGSWSGSQPECGVISC 2893
Query: 530 GTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCP 589
G P + V+ + + S + C Y+ G C+ +G W+ P C + +C
Sbjct: 2894 GNPGTPSNARVVFSDGLVFSSSIVYECREGYYATGLLSRHCSVNGTWTGSDPECLVINCG 2953
Query: 590 EPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGE--PNLVCQQDGEWSGDSPTCEYIDCG 647
+P +P+ G D+ + T+ + C G+ + L C +D W+G P C+ + C
Sbjct: 2954 DPGIPANGLRLGNDFRYNKTVTYQCVPGYMMESHRVSVLSCTKDRTWNGTKPVCKALMCK 3013
Query: 648 KLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCS 707
P +P G +++ GS + Y+C Y+L P TC W+ P+C + C
Sbjct: 3014 PPPLIPNG--KVVGSDFMWGSSVTYACLEGYQLSLPAVFTCEGNGSWTGELPQCFPVFCG 3071
Query: 708 DPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTC 767
DP V S G D G +YR + V + C ++G C
Sbjct: 3072 DPGVP------------SRGR-------REDRGFSYR--SSVSFSCHPPLVLVGSPRRFC 3110
Query: 768 EDNGQWSGTTPTC---QYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIR 824
+ +G WSGT P+C C +PG + G + S G+T ++C + + L+G
Sbjct: 3111 QSDGTWSGTQPSCIDPTLTTCADPGVPQFG-IQNNSQGYQVGSTVLFRCQKGYLLQGSTT 3169
Query: 825 RMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLK-G 883
R C N TWS PP C C P A G L + S+G Y C+ G++LK G
Sbjct: 3170 RTCLPNLTWSGTPPDCVPHHCRQPETPTHANVGALDLP---SMGYTLIYSCQEGFSLKGG 3226
Query: 884 HQTRTCISKGQWNGTVPVCIPI 905
+ RTC + G W G P+C+ +
Sbjct: 3227 SEHRTCKADGSWTGKPPICLEV 3248
Score = 287 bits (704), Expect = 1e-76
Identities = 170/601 (28%), Positives = 274/601 (45%), Gaps = 42/601 (6%)
Query: 372 GSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRTTH 431
G+ ++ C G+ L+G + R C +G WSG+ C +CG PI +G + +N +
Sbjct: 2677 GATAIFSCNSGYTLVGSRVRECMANGLWSGSEVRCLAGHCGTPEPIVNGHING-ENYSYR 2735
Query: 432 GARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGS 491
G+ +Y C F L+G R C + W G+ P C+ C P + ++ ++ + + G+
Sbjct: 2736 GS-VVYQCNAGFRLIGMSVRICQQDHHWSGKTPFCVLVSCGHPGSPPHSQMSGDSYTVGA 2794
Query: 492 LASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVN---CGTPTIHKGSFVLINGTTTY 548
+ Y+C L G+++ C L G W+G P C + CG P I + + +
Sbjct: 2795 VVRYSCIGKRTLVGNSTRMCGLDGHWTGSLPHCSGTSVGVCGDPGIPAHG-IRLGDSFDP 2853
Query: 549 GSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFDYYVHS 608
G++ +F+CE + L G+ E C +G WS P C + SC P PS + D V S
Sbjct: 2854 GTVMRFSCEAGHVLRGSSERTCQANGSWSGSQPECGVISCGNPGTPSNARVVFSDGLVFS 2913
Query: 609 T-INFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLG 667
+ I + C G+ G + C +G W+G P C I+CG P +P + L N +
Sbjct: 2914 SSIVYECREGYYATGLLSRHCSVNGTWTGSDPECLVINCGD-PGIPANGLRLGNDFRY-N 2971
Query: 668 SVIQYSCTTNYRLVGPVRR--TCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRS 725
+ Y C Y + +CT++ W+ + P C+ + C P + V
Sbjct: 2972 KTVTYQCVPGYMMESHRVSVLSCTKDRTWNGTKPVCKALMCKPPPLIPNGKV-------- 3023
Query: 726 HGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDC 785
VG+ + G+ V Y C +GY++ ++ TCE NG W+G P C V C
Sbjct: 3024 -------------VGSDFMWGSSVTYACLEGYQLSLPAVFTCEGNGSWTGELPQCFPVFC 3070
Query: 786 GNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKE--- 842
G+PG G+ Y ++ + C L G RR CQ +GTWS P C +
Sbjct: 3071 GDPGVPSRGR--REDRGFSYRSSVSFSCHPPLVLVGSPRRFCQSDGTWSGTQPSCIDPTL 3128
Query: 843 ITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVC 902
TC DP G+ + +G ++C++GY L+G TRTC+ W+GT P C
Sbjct: 3129 TTCADPGV---PQFGIQNNSQGYQVGSTVLFRCQKGYLLQGSTTRTCLPNLTWSGTPPDC 3185
Query: 903 IPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQ-RVGPFLRKCLDDGRWSGEEPS 961
+P CR P + + + ++ G ++ Y C + + G R C DG W+G+ P
Sbjct: 3186 VPHHCRQPETPTHANVGALDLPSM-GYTLIYSCQEGFSLKGGSEHRTCKADGSWTGKPPI 3244
Query: 962 C 962
C
Sbjct: 3245 C 3245
Score = 223 bits (545), Expect = 3e-57
Identities = 156/554 (28%), Positives = 232/554 (41%), Gaps = 49/554 (8%)
Query: 429 TTHGARALYSCRENFTLVGNPERTCG--DEG--IWDGEAPRCLFDWCPDPPAVSNASVTV 484
T G + C + LVG+ C +G +W P C C P A N V
Sbjct: 2485 TQPGGSIHFGCNAGYRLVGHSMAICTRHPQGYHLWSEAIPLCQALSCGLPEAPKNGMVFG 2544
Query: 485 NGHKAGSLASYTCENGHILSGSTSVT--CTLGGAWSG--VPPSCKYVNC---GTPTIHKG 537
+ G+ A Y+C G+ L T C G WS VPP C V C + ++ G
Sbjct: 2545 KEYTVGTKAMYSCSEGYHLQAGAEATAECLDTGLWSNRNVPPQCVPVTCPDVSSISVEHG 2604
Query: 538 SFVLINGTT-TYGSIAQFTCEPDYWLNGAEELVCNRDGKWSY--DIPSCELTSCPEPEVP 594
+ LI T + + C+P Y+ G + C +GKWS P+C + SC E +P
Sbjct: 2605 RWRLIFETQYQFQAQLMLICDPGYYYTGQRVIRCQANGKWSLGDSTPTCRIISCGELPIP 2664
Query: 595 SGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPY 654
G+ +T F C +G+ L+G C +G WSG C CG +
Sbjct: 2665 PNGHRIGTLSVYGATAIFSCNSGYTLVGSRVRECMANGLWSGSEVRCLAGHCGTPEPIVN 2724
Query: 655 GTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEK 714
G + N ++ GSV+ Y C +RL+G R C ++ WS +P C + C P
Sbjct: 2725 GHINGEN-YSYRGSVV-YQCNAGFRLIGMSVRICQQDHHWSGKTPFCVLVSCGHPGSPPH 2782
Query: 715 SIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWS 774
S +S G++Y +GA+V+Y C ++G S C +G W+
Sbjct: 2783 SQMS---------------------GDSYTVGAVVRYSCIGKRTLVGNSTRMCGLDGHWT 2821
Query: 775 GTTPTCQYVD---CGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENG 831
G+ P C CG+PG +G + L ++ G + C+ L G R CQ NG
Sbjct: 2822 GSLPHCSGTSVGVCGDPGIPAHG-IRL-GDSFDPGTVMRFSCEAGHVLRGSSERTCQANG 2879
Query: 832 TWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCIS 891
+WS P C I+C +P A +V + L Y+C GY G +R C
Sbjct: 2880 SWSGSQPECGVISCGNPGTPSNAR---VVFSDGLVFSSSIVYECREGYYATGLLSRHCSV 2936
Query: 892 KGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLR--KC 949
G W G+ P C+ I+C PG NG + + N + +V Y C+ Y + C
Sbjct: 2937 NGTWTGSDPECLVINCGDPGIPANG-LRLGNDFR-YNKTVTYQCVPGYMMESHRVSVLSC 2994
Query: 950 LDDGRWSGEEPSCE 963
D W+G +P C+
Sbjct: 2995 TKDRTWNGTKPVCK 3008
Score = 184 bits (449), Expect = 1e-45
Identities = 113/362 (31%), Positives = 160/362 (44%), Gaps = 12/362 (3%)
Query: 352 TCGSPDKLLNTTILGNDYDV-GSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVN 410
+CG+P N ++ +D V S IVY+C EG+ G SRHC +G W+G+ P C +N
Sbjct: 2892 SCGNPGTPSNARVVFSDGLVFSSSIVYECREGYYATGLLSRHCSVNGTWTGSDPECLVIN 2951
Query: 411 CGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPER--TCGDEGIWDGEAPRCLF 468
CG P + + N + Y C + + + +C + W+G P C
Sbjct: 2952 CGD--PGIPANGLRLGNDFRYNKTVTYQCVPGYMMESHRVSVLSCTKDRTWNGTKPVCKA 3009
Query: 469 DWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVN 528
C PP + N V + GS +Y C G+ LS TC G+W+G P C V
Sbjct: 3010 LMCKPPPLIPNGKVVGSDFMWGSSVTYACLEGYQLSLPAVFTCEGNGSWTGELPQCFPVF 3069
Query: 529 CGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSC---EL 585
CG P + G + Y S F+C P L G+ C DG WS PSC L
Sbjct: 3070 CGDPGVPSRGRREDRGFS-YRSSVSFSCHPPLVLVGSPRRFCQSDGTWSGTQPSCIDPTL 3128
Query: 586 TSCPEPEVPSGGYME-AFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYI 644
T+C +P VP G + Y V ST+ F C+ G+ L G C + WSG P C
Sbjct: 3129 TTCADPGVPQFGIQNNSQGYQVGSTVLFRCQKGYLLQGSTTRTCLPNLTWSGTPPDCVPH 3188
Query: 645 DCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVG-PVRRTCTEEFQWSDSSPRCEE 703
C + T + + L+ +G + YSC + L G RTC + W+ P C E
Sbjct: 3189 HCRQPETPTHANVGALD-LPSMGYTLIYSCQEGFSLKGGSEHRTCKADGSWTGKPPICLE 3247
Query: 704 IR 705
+R
Sbjct: 3248 VR 3249
Score = 167 bits (405), Expect = 2e-40
Identities = 153/631 (24%), Positives = 247/631 (39%), Gaps = 57/631 (9%)
Query: 353 CGSPDKLLNTTIL--GNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGF--WSGAPPSCKY 408
C P L N ++ ++++G + Y+C G L+G++ CK + + G PP C+
Sbjct: 2294 CPPPTILPNAEVVTENEEFNIGDIVRYRCLPGFTLVGNEILTCKLGTYLQFEGPPPICE- 2352
Query: 409 VNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCG-DEGIWDGEAPRCL 467
V+C + D ++ +C ++ + P+ + E
Sbjct: 2353 VHCPTNELLTDSTGVILSQSYPGSYPQFQTC--SWLVRVEPDYNISLTVEYFLSEKQYDE 2410
Query: 468 FDWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYV 527
F+ P S ++G+ + L + N L S+ G + S Y
Sbjct: 2411 FEIFDGPSGQSPLLKALSGNYSAPLIVTSSSNSVYLRWSSDHAYNRKG--FKIRYSAPY- 2467
Query: 528 NCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGK----WSYDIPSC 583
C P F+L +T G F C Y L G +C R + WS IP C
Sbjct: 2468 -CSLPRAPLHGFILGQTSTQPGGSIHFGCNAGYRLVGHSMAICTRHPQGYHLWSEAIPLC 2526
Query: 584 ELTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLI--GEPNLVCQQDGEWSGDS--P 639
+ SC PE P G + +Y V + + C G+ L E C G WS + P
Sbjct: 2527 QALSCGLPEAPKNGMVFGKEYTVGTKAMYSCSEGYHLQAGAEATAECLDTGLWSNRNVPP 2586
Query: 640 TCEYIDCGKLPTL--PYGTMELLNGTTH-LGSVIQYSCTTNYRLVGPVRRTCTEEFQWS- 695
C + C + ++ +G L+ T + + + C Y G C +WS
Sbjct: 2587 QCVPVTCPDVSSISVEHGRWRLIFETQYQFQAQLMLICDPGYYYTGQRVIRCQANGKWSL 2646
Query: 696 -DSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCE 754
DS+P C I C + + + N GH +G GA + C
Sbjct: 2647 GDSTPTCRIISCGE--------LPIPPN----GHR---------IGTLSVYGATAIFSCN 2685
Query: 755 KGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCD 814
GY ++G + C NG WSG+ C CG P I NG + N ++ G+ YQC+
Sbjct: 2686 SGYTLVGSRVRECMANGLWSGSEVRCLAGHCGTPEPIVNGHIN-GENYSYRGSVV-YQCN 2743
Query: 815 ENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQ 874
+ L G+ R+CQ++ WS + P C ++C P + + + + ++G Y
Sbjct: 2744 AGFRLIGMSVRICQQDHHWSGKTPFCVLVSCGHPGSPPHS----QMSGDSYTVGAVVRYS 2799
Query: 875 CERGYNLKGHQTRTCISKGQWNGTVPVCIPID---CRSPGNIENGKIVISNGSTLFGSSV 931
C L G+ TR C G W G++P C C PG +G + S G+ +
Sbjct: 2800 CIGKRTLVGNSTRMCGLDGHWTGSLPHCSGTSVGVCGDPGIPAHG--IRLGDSFDPGTVM 2857
Query: 932 EYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
+ C + + G R C +G WSG +P C
Sbjct: 2858 RFSCEAGHVLRGSSERTCQANGSWSGSQPEC 2888
Score = 148 bits (359), Expect = 9e-35
Identities = 144/521 (27%), Positives = 209/521 (40%), Gaps = 66/521 (12%)
Query: 471 CPDPPAVSNASVTVNGHK--AGSLASYTCENGHILSGSTSVTCTLGG--AWSGVPPSCKY 526
CP P + NA V + G + Y C G L G+ +TC LG + G PP C+
Sbjct: 2294 CPPPTILPNAEVVTENEEFNIGDIVRYRCLPGFTLVGNEILTCKLGTYLQFEGPPPICE- 2352
Query: 527 VNCGTPTIHKGSFVLINGTTTYGSIAQF-TC------EPDYWLNGAEELVCNRDGKWSYD 579
V+C T + S +I + GS QF TC EPDY ++ E + ++
Sbjct: 2353 VHCPTNELLTDSTGVILSQSYPGSYPQFQTCSWLVRVEPDYNISLTVEYFLSEKQYDEFE 2412
Query: 580 IPSCELTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSP 639
I P + SG Y V S+ N + + + ++ + +P
Sbjct: 2413 IFDGPSGQSPLLKALSGNYSAPL--IVTSSSN----SVYLRWSSDHAYNRKGFKIRYSAP 2466
Query: 640 TCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQ----WS 695
C LP P L +T G I + C YRLVG CT Q WS
Sbjct: 2467 YCS------LPRAPLHGFILGQTSTQPGGSIHFGCNAGYRLVGHSMAICTRHPQGYHLWS 2520
Query: 696 DSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEK 755
++ P C+ + C P + +V G Y +G Y C +
Sbjct: 2521 EAIPLCQALSCGLPEAPKNGMV---------------------FGKEYTVGTKAMYSCSE 2559
Query: 756 GYKVIG--ESLSTCEDNGQWSGTT--PTCQYVDCGNPGRI--ENGKVTLPSNATF-YGAT 808
GY + E+ + C D G WS P C V C + I E+G+ L + + A
Sbjct: 2560 GYHLQAGAEATAECLDTGLWSNRNVPPQCVPVTCPDVSSISVEHGRWRLIFETQYQFQAQ 2619
Query: 809 AFYQCDENWELEGVIRRMCQENGTWSL--EPPICKEITCPDPSAQIKAGSGLLVVTSTLS 866
CD + G CQ NG WSL P C+ I+C + I + TLS
Sbjct: 2620 LMLICDPGYYYTGQRVIRCQANGKWSLGDSTPTCRIISCGE--LPIPPNGHRI---GTLS 2674
Query: 867 I-GGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGST 925
+ G A + C GY L G + R C++ G W+G+ C+ C +P I NG I N S
Sbjct: 2675 VYGATAIFSCNSGYTLVGSRVRECMANGLWSGSEVRCLAGHCGTPEPIVNGHINGENYS- 2733
Query: 926 LFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCELAT 966
+ SV Y C + ++ +G +R C D WSG+ P C L +
Sbjct: 2734 -YRGSVVYQCNAGFRLIGMSVRICQQDHHWSGKTPFCVLVS 2773
Score = 85.8 bits (203), Expect = 7e-16
Identities = 56/185 (30%), Positives = 79/185 (42%), Gaps = 10/185 (5%)
Query: 347 QYLPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSC 406
Q P CG P + S + + C +L+G R C+ DG WSG PSC
Sbjct: 3064 QCFPVFCGDPGVPSRGRREDRGFSYRSSVSFSCHPPLVLVGSPRRFCQSDGTWSGTQPSC 3123
Query: 407 KYVNCGGLTPIEDGDVAL--IDNRTTH---GARALYSCRENFTLVGNPERTCGDEGIWDG 461
LT D V I N + G+ L+ C++ + L G+ RTC W G
Sbjct: 3124 IDPT---LTTCADPGVPQFGIQNNSQGYQVGSTVLFRCQKGYLLQGSTTRTCLPNLTWSG 3180
Query: 462 EAPRCLFDWCPDPPAVSNASV-TVNGHKAGSLASYTCENGHILSG-STSVTCTLGGAWSG 519
P C+ C P ++A+V ++ G Y+C+ G L G S TC G+W+G
Sbjct: 3181 TPPDCVPHHCRQPETPTHANVGALDLPSMGYTLIYSCQEGFSLKGGSEHRTCKADGSWTG 3240
Query: 520 VPPSC 524
PP C
Sbjct: 3241 KPPIC 3245
Score = 72.9 bits (171), Expect = 6e-12
Identities = 96/395 (24%), Positives = 166/395 (42%), Gaps = 45/395 (11%)
Query: 585 LTSCPEPEV-PSGGYM-EAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDG--EWSGDSPT 640
LT CP P + P+ + E ++ + + + C G L+G L C+ ++ G P
Sbjct: 2291 LTKCPPPTILPNAEVVTENEEFNIGDIVRYRCLPGFTLVGNEILTCKLGTYLQFEGPPPI 2350
Query: 641 CEYIDCGKLPTLPYGTMELLNGTTHLGSVIQY-SCTTNYRLVGPVRRTCTEEFQWSDSSP 699
CE + C L T +L+ ++ GS Q+ +C+ R+ + T E+ S+
Sbjct: 2351 CE-VHCPTNELLTDSTGVILS-QSYPGSYPQFQTCSWLVRVEPDYNISLTVEYFLSEK-- 2406
Query: 700 RCEEIRCSD-PIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYK 758
+ +E D P + +++GN + LI TS + V R + Y KG+K
Sbjct: 2407 QYDEFEIFDGPSGQSPLLKALSGN---YSAPLIVTSSSNSV--YLRWSSDHAYN-RKGFK 2460
Query: 759 VIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWE 818
+ ++S P C G I T P + +G A Y+ +
Sbjct: 2461 I------------RYS--APYCSLPRAPLHGFILGQTSTQPGGSIHFGCNAGYRLVGH-- 2504
Query: 819 LEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERG 878
+ R Q WS P+C+ ++C P A K G +V ++G +A Y C G
Sbjct: 2505 SMAICTRHPQGYHLWSEAIPLCQALSCGLPEAP-KNG---MVFGKEYTVGTKAMYSCSEG 2560
Query: 879 YNLK--GHQTRTCISKGQWN--GTVPVCIPIDCR--SPGNIENGK-IVISNGSTLFGSSV 931
Y+L+ T C+ G W+ P C+P+ C S ++E+G+ +I F + +
Sbjct: 2561 YHLQAGAEATAECLDTGLWSNRNVPPQCVPVTCPDVSSISVEHGRWRLIFETQYQFQAQL 2620
Query: 932 EYYCLSQYQRVGPFLRKCLDDGRWS-GEE-PSCEL 964
C Y G + +C +G+WS G+ P+C +
Sbjct: 2621 MLICDPGYYYTGQRVIRCQANGKWSLGDSTPTCRI 2655
Score = 54.8 bits (126), Expect = 2e-06
Identities = 31/87 (35%), Positives = 41/87 (47%), Gaps = 7/87 (8%)
Query: 576 WSYDIPSCE---LTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQ-- 630
W D P CE L CP+PE + G + Y V ++ F C G++L G P L CQ
Sbjct: 2109 WDLD-PGCEAYELQECPDPEPFANGIVRGAGYNVGQSVTFECLPGYQLTGHPVLTCQHGT 2167
Query: 631 DGEWSGDSPTCEYIDCGKLPTLPYGTM 657
+ W P CE + CG T GT+
Sbjct: 2168 NRNWDHPLPKCE-VPCGGNITSSNGTV 2193
Score = 52.8 bits (121), Expect = 6e-06
Identities = 24/57 (42%), Positives = 30/57 (52%), Gaps = 2/57 (3%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
CG+P P NARV + +V + VYEC EGY G R C++ G WT P C
Sbjct: 2893 CGNPGTPSNARVVF--SDGLVFSSSIVYECREGYYATGLLSRHCSVNGTWTGSDPEC 2947
Score = 50.8 bits (116), Expect = 3e-05
Identities = 21/69 (30%), Positives = 37/69 (53%), Gaps = 2/69 (2%)
Query: 575 KWSYDIPSCELTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEW 634
K SY+ E SC +P +P+ G E ++ T+ F C+ +L+G+ + CQ++ +W
Sbjct: 510 KASYE--EIEQGSCGDPGIPAYGRREGSRFHHGDTLKFECQPAFELVGQKAITCQKNNQW 567
Query: 635 SGDSPTCEY 643
S P C +
Sbjct: 568 SAKKPGCVF 576
Score = 50.4 bits (115), Expect = 3e-05
Identities = 24/71 (33%), Positives = 40/71 (56%), Gaps = 3/71 (4%)
Query: 578 YDIPSCELTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLI-GEPNLVCQQDGEWSG 636
Y+ + + C +P +P G D+YV + + F C++G+ L GEP L C+ + +WS
Sbjct: 857 YETITLQSDHCLDPGIPVNGQRHGNDFYVGALVTFSCDSGYTLSDGEP-LECEPNFQWSR 915
Query: 637 DSPTCEYIDCG 647
P+CE + CG
Sbjct: 916 ALPSCEAL-CG 925
Score = 50.0 bits (114), Expect = 5e-05
Identities = 54/224 (24%), Positives = 87/224 (38%), Gaps = 16/224 (7%)
Query: 432 GARALYSCRENFTLVGNPERTC----GDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGH 487
GA + C + L G+PE C G W+ AP C+ C ++ G
Sbjct: 1754 GAIVRFECNSGYALQGSPEIECLPVPGALAQWNVSAPTCVVP-CGGNLTERRGTILSPGF 1812
Query: 488 KAGSLASYTCENGHILSGSTSVTCTLGGAWSGVP-PSCKYVNCGTPTIHK-GSFVLINGT 545
L S C ++ + + + S + + T+ GSF +GT
Sbjct: 1813 PEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQNWDSLEVFDGADNTVTMLGSF---SGT 1869
Query: 546 TTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFDYY 605
T ++ T Y L+ ++ + G + + + L+SCPEP VPS G Y
Sbjct: 1870 TV-PALLNSTSNQLY-LHFYSDISVSAAG-FHLEYKTVGLSSCPEPAVPSNGVKTGERYL 1926
Query: 606 VHSTINFHCEAGHKLIGEPNLVCQQD--GEWSGDSPTCEYIDCG 647
V+ ++F CE G+ L G ++ C W+ P C CG
Sbjct: 1927 VNDVVSFQCEPGYALQGHAHISCMPGTVRRWNYPPPLC-IAQCG 1969
Score = 49.6 bits (113), Expect = 6e-05
Identities = 26/67 (38%), Positives = 37/67 (55%), Gaps = 3/67 (4%)
Query: 740 GNTYRIGALVKYRCEKGYKVI-GESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTL 798
GN + +GALV + C+ GY + GE L CE N QWS P+C+ + CG + +G +
Sbjct: 880 GNDFYVGALVTFSCDSGYTLSDGEPLE-CEPNFQWSRALPSCEAL-CGGFIQGSSGTILS 937
Query: 799 PSNATFY 805
P FY
Sbjct: 938 PGFPDFY 944
Score = 49.2 bits (112), Expect = 8e-05
Identities = 60/241 (24%), Positives = 87/241 (36%), Gaps = 17/241 (7%)
Query: 740 GNTYRIGALVKYRCEKGYKVIGESLSTCE--DNGQWSGTTPTCQYVDCGNPGRIENGKVT 797
G Y +G V + C GY++ G + TC+ N W P C+ V CG NG V
Sbjct: 2136 GAGYNVGQSVTFECLPGYQLTGHPVLTCQHGTNRNWDHPLPKCE-VPCGGNITSSNGTVY 2194
Query: 798 LPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSG 857
P + Y ++ D W + I + N + P IT D Q G
Sbjct: 2195 SPGFPSPYSSSQ----DCVWLITVPIGHGVRLNLSLLQTEPSGDFITIWDGPQQTAPRLG 2250
Query: 858 LLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGK 917
+ T S+ + LK H R + G + C P + N +
Sbjct: 2251 VF----TRSMAKKTVQSSSNQVLLKFH--RDAATGGIFAIAFSAYPLTKCPPPTILPNAE 2304
Query: 918 IVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDG--RWSGEEPSCEL--ATNEAVDSG 973
+V N G V Y CL + VG + C ++ G P CE+ TNE +
Sbjct: 2305 VVTENEEFNIGDIVRYRCLPGFTLVGNEILTCKLGTYLQFEGPPPICEVHCPTNELLTDS 2364
Query: 974 T 974
T
Sbjct: 2365 T 2365
Score = 47.6 bits (108), Expect = 2e-04
Identities = 63/277 (22%), Positives = 106/277 (38%), Gaps = 35/277 (12%)
Query: 646 CGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTC----TEEFQWSDSSPRC 701
CG LP G + T +LG ++YSC + L G TC W P C
Sbjct: 139 CGNPGRLPNGIQQ--GSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPSC 196
Query: 702 E-EIRCSDPIVAEKSIVSVTG-NDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKV 759
+ C + + I+S H + + ++G+T + + ++ E GY
Sbjct: 197 RADDACGGTLRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIAL-VFIDFQLEDGYDF 255
Query: 760 IGESLSTCEDNGQW-SGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWE 818
+ ++ E + W +G + + N R+ T N G +A YQ + E
Sbjct: 256 L--EVTGTEGSSLWFTGASLPAPVISSKNWLRLH---FTSDGNHRQRGFSAQYQVKKQIE 310
Query: 819 LE--GVIRRMCQENGTWSLEPPICKEI-------TCPDPSAQIKAGSGLLVVTSTLSIGG 869
L+ GV ++N S + + ++ CPDP + G L S +G
Sbjct: 311 LKSRGVKLMPSKDN---SQKTSVLTQVGVSQGHNMCPDPGIP-ERGKRL---GSDFRLGS 363
Query: 870 EAHYQCERGYNLKGHQTRTCISKGQ----WNGTVPVC 902
+ C GY+L+G + TC+ W+ PVC
Sbjct: 364 SVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVC 400
Score = 45.6 bits (103), Expect = 0.001
Identities = 23/67 (34%), Positives = 32/67 (47%), Gaps = 2/67 (2%)
Query: 349 LPPTCGSPDKLLNTTILGNDY-DVGSRIVYKCPEGHMLLG-DKSRHCKKDGFWSGAPPSC 406
+P C P+ + + D +G ++Y C EG L G + R CK DG W+G PP C
Sbjct: 3186 VPHHCRQPETPTHANVGALDLPSMGYTLIYSCQEGFSLKGGSEHRTCKADGSWTGKPPIC 3245
Query: 407 KYVNCGG 413
V G
Sbjct: 3246 LEVRPNG 3252
Score = 44.8 bits (101), Expect = 0.002
Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 3/76 (3%)
Query: 584 ELTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGE--WSGDSPTC 641
+L C EPEVP+ + + V T+ F C G++L G + C WS P C
Sbjct: 1035 DLEPCEEPEVPAYSIRKGLQFGVGDTLTFSCFPGYRLEGTARITCLGGRRRLWSSPLPRC 1094
Query: 642 EYIDCGKLPTLPYGTM 657
+CG T GT+
Sbjct: 1095 -VAECGNSVTGTQGTL 1109
Score = 44.4 bits (100), Expect = 0.002
Identities = 27/90 (30%), Positives = 41/90 (45%), Gaps = 3/90 (3%)
Query: 333 NDVGCNLDYLHWICQYLPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRH 392
+D+G L Y Q C P +N GND+ VG+ + + C G+ L +
Sbjct: 849 SDIGFQLRYETITLQ--SDHCLDPGIPVNGQRHGNDFYVGALVTFSCDSGYTLSDGEPLE 906
Query: 393 CKKDGFWSGAPPSCKYVNCGGLTPIEDGDV 422
C+ + WS A PSC+ + CGG G +
Sbjct: 907 CEPNFQWSRALPSCEAL-CGGFIQGSSGTI 935
Score = 44.0 bits (99), Expect = 0.003
Identities = 20/70 (28%), Positives = 34/70 (48%), Gaps = 1/70 (1%)
Query: 737 RDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKV 796
R G+ + G +K+ C+ ++++G+ TC+ N QWS P C + C +G V
Sbjct: 531 RREGSRFHHGDTLKFECQPAFELVGQKAITCQKNNQWSAKKPGCVF-SCFFNFTSPSGVV 589
Query: 797 TLPSNATFYG 806
P+ YG
Sbjct: 590 LSPNYPEDYG 599
Score = 43.6 bits (98), Expect = 0.004
Identities = 23/62 (37%), Positives = 31/62 (50%), Gaps = 4/62 (6%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC-GT 60
CGHP PP++++S ++ G + Y C L G R C L G WT P C GT
Sbjct: 2774 CGHPGSPPHSQMS---GDSYTVGAVVRYSCIGKRTLVGNSTRMCGLDGHWTGSLPHCSGT 2830
Query: 61 NV 62
+V
Sbjct: 2831 SV 2832
Score = 42.3 bits (95), Expect = 0.009
Identities = 24/70 (34%), Positives = 35/70 (50%), Gaps = 6/70 (8%)
Query: 582 SCELTSCPEPEVPSGGY-MEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGE---WSGD 637
S EL C +P P GY + ++ S+++F C+ G+ L G L+C GE W
Sbjct: 1205 SFELIKCEDPGTPKFGYKVHDEGHFAGSSVSFSCDPGYSLRGSEELLC-LSGERRTWDRP 1263
Query: 638 SPTCEYIDCG 647
PTC +CG
Sbjct: 1264 LPTC-VAECG 1272
Score = 41.9 bits (94), Expect = 0.012
Identities = 20/52 (38%), Positives = 28/52 (53%), Gaps = 5/52 (9%)
Query: 2 CGHPAVPPNA-RVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWT 52
CG +PPN R+ + V G A++ C+ GY L G+R REC G W+
Sbjct: 2658 CGELPIPPNGHRIGTLS----VYGATAIFSCNSGYTLVGSRVRECMANGLWS 2705
Score = 41.5 bits (93), Expect = 0.016
Identities = 18/58 (31%), Positives = 29/58 (50%), Gaps = 3/58 (5%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCG 59
CG P +P + I ++ GT+ + C+ G+ L G+ +R C G W+ P CG
Sbjct: 2835 CGDPGIPAHG---IRLGDSFDPGTVMRFSCEAGHVLRGSSERTCQANGSWSGSQPECG 2889
Score = 41.5 bits (93), Expect = 0.016
Identities = 20/58 (34%), Positives = 28/58 (48%), Gaps = 3/58 (5%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQ-RECTLRGDWTLEPPFC 58
C P P +A V + ++ G +Y C EG+ L G + R C G WT +PP C
Sbjct: 3190 CRQPETPTHANVGALDLPSM--GYTLIYSCQEGFSLKGGSEHRTCKADGSWTGKPPIC 3245
Score = 40.7 bits (91), Expect = 0.028
Identities = 18/63 (28%), Positives = 28/63 (44%), Gaps = 4/63 (6%)
Query: 588 CPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGE----WSGDSPTCEY 643
CP+P +P G D+ + S++ F C G+ L G + C + + WS P C
Sbjct: 343 CPDPGIPERGKRLGSDFRLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRA 402
Query: 644 IDC 646
C
Sbjct: 403 RMC 405
Score = 40.7 bits (91), Expect = 0.028
Identities = 20/62 (32%), Positives = 30/62 (48%), Gaps = 1/62 (1%)
Query: 469 DWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVN 528
D C DP N N G+L +++C++G+ LS + C WS PSC+ +
Sbjct: 865 DHCLDPGIPVNGQRHGNDFYVGALVTFSCDSGYTLSDGEPLECEPNFQWSRALPSCEAL- 923
Query: 529 CG 530
CG
Sbjct: 924 CG 925
Score = 40.7 bits (91), Expect = 0.028
Identities = 23/82 (28%), Positives = 35/82 (42%), Gaps = 5/82 (6%)
Query: 580 IPSCELTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQD----GEWS 635
+P T C P G D+ V + + F C +G+ L G P + C +W+
Sbjct: 1727 VPRTSATQCSSVPEPRYGKRLGSDFSVGAIVRFECNSGYALQGSPEIECLPVPGALAQWN 1786
Query: 636 GDSPTCEYIDCGKLPTLPYGTM 657
+PTC + CG T GT+
Sbjct: 1787 VSAPTC-VVPCGGNLTERRGTI 1807
Score = 40.3 bits (90), Expect = 0.037
Identities = 27/99 (27%), Positives = 44/99 (44%), Gaps = 6/99 (6%)
Query: 331 LWNDVGCNLDYLHWICQYLPP-TCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDK 389
L +D + H + LP TCG+P +L N G+ +++G ++ Y C G L G
Sbjct: 116 LISDYAVSAQGFHATYEALPSHTCGNPGRLPNGIQQGSTFNLGDKVRYSCNLGFFLEGHA 175
Query: 390 SRHC----KKDGFWSGAPPSCKYVN-CGGLTPIEDGDVA 423
C + W PSC+ + CGG + G ++
Sbjct: 176 VLTCHAGSENSATWDFPLPSCRADDACGGTLRGQSGIIS 214
Score = 39.5 bits (88), Expect = 0.064
Identities = 20/63 (31%), Positives = 27/63 (42%), Gaps = 4/63 (6%)
Query: 471 CPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTC----TLGGAWSGVPPSCKY 526
CPDP + + GS +TC G+ L GS +TC + AWS P C+
Sbjct: 343 CPDPGIPERGKRLGSDFRLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRA 402
Query: 527 VNC 529
C
Sbjct: 403 RMC 405
Score = 39.5 bits (88), Expect = 0.064
Identities = 27/104 (25%), Positives = 45/104 (43%), Gaps = 10/104 (9%)
Query: 523 SCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVC--NRDGKWSYDI 580
S + + C P K + + + GS F+C+P Y L G+EEL+C W +
Sbjct: 1205 SFELIKCEDPGTPKFGYKVHDEGHFAGSSVSFSCDPGYSLRGSEELLCLSGERRTWDRPL 1264
Query: 581 PSCELTSC-------PEPEVPSGGYMEAFDYYVHSTINFHCEAG 617
P+C + C +V S GY +++ ++ EAG
Sbjct: 1265 PTC-VAECGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAG 1307
Score = 39.5 bits (88), Expect = 0.064
Identities = 31/126 (24%), Positives = 50/126 (39%), Gaps = 9/126 (7%)
Query: 292 RTWQW-VDGELVSKPSWGKDQPNNYNGEQNCVVLDGGRGWLWNDVGCNLDYLHWICQYLP 350
R W V+ ++ K G P + + N VVL + + G + +
Sbjct: 1327 RIWDGPVESGVLLKELSGPALPKDLHSTFNSVVLQFSTDFFTSKQGFAIQF----SVSTA 1382
Query: 351 PTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKK---DGFWSGAPPSCK 407
+C P N + G+ ++ G V++C G+ L G C K FW +PP+C
Sbjct: 1383 TSCNDPGIPQNGSRSGDSWEAGDSTVFQCDPGYALQGSAEISCVKIENRFFWQPSPPTC- 1441
Query: 408 YVNCGG 413
CGG
Sbjct: 1442 IAPCGG 1447
Score = 39.5 bits (88), Expect = 0.064
Identities = 21/72 (29%), Positives = 32/72 (44%), Gaps = 3/72 (4%)
Query: 353 CGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCK--KDGFWSGAPPSCKYVN 410
C P+ N + G Y+VG + ++C G+ L G C+ + W P C+ V
Sbjct: 2123 CPDPEPFANGIVRGAGYNVGQSVTFECLPGYQLTGHPVLTCQHGTNRNWDHPLPKCE-VP 2181
Query: 411 CGGLTPIEDGDV 422
CGG +G V
Sbjct: 2182 CGGNITSSNGTV 2193
Score = 39.1 bits (87), Expect = 0.085
Identities = 24/63 (38%), Positives = 31/63 (49%), Gaps = 8/63 (12%)
Query: 844 TCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCI----SKGQWNGTV 899
+C DP + IK G+ V S L +G Y C GY ++G T +CI K WN
Sbjct: 1557 SCFDPGS-IKNGTR---VGSDLKLGSSVTYYCHGGYEVEGTSTLSCILGPDGKPVWNNPR 1612
Query: 900 PVC 902
PVC
Sbjct: 1613 PVC 1615
Score = 39.1 bits (87), Expect = 0.085
Identities = 21/62 (33%), Positives = 29/62 (46%), Gaps = 3/62 (4%)
Query: 471 CPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLG--GAWSGVPPSCKYVN 528
CPDP +N V G+ G ++ C G+ L+G +TC G W P C+ V
Sbjct: 2123 CPDPEPFANGIVRGAGYNVGQSVTFECLPGYQLTGHPVLTCQHGTNRNWDHPLPKCE-VP 2181
Query: 529 CG 530
CG
Sbjct: 2182 CG 2183
Score = 38.7 bits (86), Expect = 0.11
Identities = 56/246 (22%), Positives = 85/246 (34%), Gaps = 24/246 (9%)
Query: 352 TCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHC--KKDG--FWSGAPPSCK 407
+C P + N T +G+D +GS + Y C G+ + G + C DG W+ P C
Sbjct: 1557 SCFDPGSIKNGTRVGSDLKLGSSVTYYCHGGYEVEGTSTLSCILGPDGKPVWNNPRPVCT 1616
Query: 408 YVNCGGLTPIEDGDVALIDN---RTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAP 464
CGG DG V L N T G LY F V G + A
Sbjct: 1617 -APCGGQYVGSDG-VVLSPNYPQNYTSGQICLY-----FVTVPKDYVVFGQFAFFH-TAL 1668
Query: 465 RCLFDWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGG---AWSGVP 521
+ + S +++G G N ++ S G + VP
Sbjct: 1669 NDVVEVHDGHSQHSRLLSSLSGSHTGESLPLATSNQVLIKFSAKGLAPARGFHFVYQAVP 1728
Query: 522 PSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVC----NRDGKWS 577
+ P G + + G+I +F C Y L G+ E+ C +W+
Sbjct: 1729 RTSATQCSSVPEPRYGK--RLGSDFSVGAIVRFECNSGYALQGSPEIECLPVPGALAQWN 1786
Query: 578 YDIPSC 583
P+C
Sbjct: 1787 VSAPTC 1792
Score = 38.7 bits (86), Expect = 0.11
Identities = 25/61 (40%), Positives = 31/61 (50%), Gaps = 8/61 (13%)
Query: 907 CRSPGNIENGKIVISNGSTL-FGSSVEYYCLSQYQRVGPFLRKCL--DDGR--WSGEEPS 961
C PG+I+NG V GS L GSSV YYC Y+ G C+ DG+ W+ P
Sbjct: 1558 CFDPGSIKNGTRV---GSDLKLGSSVTYYCHGGYEVEGTSTLSCILGPDGKPVWNNPRPV 1614
Query: 962 C 962
C
Sbjct: 1615 C 1615
Score = 38.3 bits (85), Expect = 0.15
Identities = 27/81 (33%), Positives = 36/81 (44%), Gaps = 7/81 (8%)
Query: 626 LVCQQDGEWS--GDSPTCEYIDCGKL--PTLP-YGTMELLNGTTHLGSVIQYSCTTNYRL 680
L+ Q DG S G + E I+ G P +P YG E H G +++ C + L
Sbjct: 496 LLFQTDGSGSSLGFKASYEEIEQGSCGDPGIPAYGRRE--GSRFHHGDTLKFECQPAFEL 553
Query: 681 VGPVRRTCTEEFQWSDSSPRC 701
VG TC + QWS P C
Sbjct: 554 VGQKAITCQKNNQWSAKKPGC 574
Score = 38.3 bits (85), Expect = 0.15
Identities = 62/247 (25%), Positives = 96/247 (38%), Gaps = 43/247 (17%)
Query: 665 HLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDR 724
++G+++ +SC + Y L C FQWS + P CE + C I + G
Sbjct: 884 YVGALVTFSCDSGYTLSDGEPLECEPNFQWSRALPSCEAL-CGGFIQGSSGTILSPGFPD 942
Query: 725 SHGHTL-----IRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPT 779
+ + L I TS + V T+ + E G+ + L T +NG S T P
Sbjct: 943 FYPNNLNCTWIIETSHGKGVFFTFH-----TFHLESGHDYL---LIT--ENG--SFTQPL 990
Query: 780 CQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPI 839
Q P I G L N T A + D + EG + + LEP
Sbjct: 991 RQLTGSRLPAPISAG---LYGNFT---AQVRFISDFSMSYEGFNITFSE----YDLEP-- 1038
Query: 840 CKEITCPD-PSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCIS--KGQWN 896
C+E P+ P+ I+ G +G + C GY L+G TC+ + W+
Sbjct: 1039 CEE---PEVPAYSIRKG-------LQFGVGDTLTFSCFPGYRLEGTARITCLGGRRRLWS 1088
Query: 897 GTVPVCI 903
+P C+
Sbjct: 1089 SPLPRCV 1095
Score = 37.5 bits (83), Expect = 0.26
Identities = 14/36 (38%), Positives = 22/36 (61%)
Query: 549 GSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCE 584
G++ F+C+ Y L+ E L C + +WS +PSCE
Sbjct: 886 GALVTFSCDSGYTLSDGEPLECEPNFQWSRALPSCE 921
Score = 37.1 bits (82), Expect = 0.34
Identities = 22/63 (34%), Positives = 28/63 (44%), Gaps = 4/63 (6%)
Query: 471 CPDPPAVS-NASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLG--GAWSGVPPSCKYV 527
C DP V GH AGS S++C+ G+ L GS + C G W P+C
Sbjct: 1211 CEDPGTPKFGYKVHDEGHFAGSSVSFSCDPGYSLRGSEELLCLSGERRTWDRPLPTC-VA 1269
Query: 528 NCG 530
CG
Sbjct: 1270 ECG 1272
Score = 37.1 bits (82), Expect = 0.34
Identities = 20/65 (30%), Positives = 31/65 (47%), Gaps = 5/65 (7%)
Query: 739 VGNTYRIGALVKYRCEKGYKVIG----ESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENG 794
+G+ + +GA+V++ C GY + G E L QW+ + PTC V CG G
Sbjct: 1747 LGSDFSVGAIVRFECNSGYALQGSPEIECLPVPGALAQWNVSAPTC-VVPCGGNLTERRG 1805
Query: 795 KVTLP 799
+ P
Sbjct: 1806 TILSP 1810
Score = 36.7 bits (81), Expect = 0.45
Identities = 19/66 (28%), Positives = 33/66 (50%), Gaps = 4/66 (6%)
Query: 739 VGNTYRIGALVKYRCEKGYKVIGESLSTC----EDNGQWSGTTPTCQYVDCGNPGRIENG 794
+G+ +R+G+ V++ C +GY + G TC + WS P C+ C R +G
Sbjct: 355 LGSDFRLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRGPSG 414
Query: 795 KVTLPS 800
+T P+
Sbjct: 415 IITSPN 420
Score = 36.3 bits (80), Expect = 0.60
Identities = 21/60 (35%), Positives = 27/60 (45%), Gaps = 6/60 (10%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTL---RGDWTLEPPFC 58
C P +P N S + E AG V++CD GY L G+ + C R W PP C
Sbjct: 1385 CNDPGIPQNGSRSGDSWE---AGDSTVFQCDPGYALQGSAEISCVKIENRFFWQPSPPTC 1441
Score = 36.3 bits (80), Expect = 0.60
Identities = 19/57 (33%), Positives = 25/57 (43%), Gaps = 3/57 (5%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
CG P N + N EN VY+C+ G+ L G R C W+ + PFC
Sbjct: 2716 CGTPEPIVNGHI---NGENYSYRGSVVYQCNAGFRLIGMSVRICQQDHHWSGKTPFC 2769
Score = 35.9 bits (79), Expect = 0.79
Identities = 20/51 (39%), Positives = 27/51 (52%), Gaps = 4/51 (7%)
Query: 365 LGNDYDVGSRIVYKCPEGHMLLGDKSRHCKK--DGF--WSGAPPSCKYVNC 411
LG+D+ +GS + + C EG+ L G K C K D F WS P C+ C
Sbjct: 355 LGSDFRLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRARMC 405
Score = 35.9 bits (79), Expect = 0.79
Identities = 17/65 (26%), Positives = 31/65 (47%), Gaps = 5/65 (7%)
Query: 548 YGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELT-----SCPEPEVPSGGYMEAF 602
+G +F C+P + L G + + C ++ +WS P C + + P V S Y E +
Sbjct: 539 HGDTLKFECQPAFELVGQKAITCQKNNQWSAKKPGCVFSCFFNFTSPSGVVLSPNYPEDY 598
Query: 603 DYYVH 607
++H
Sbjct: 599 GNHLH 603
Score = 35.9 bits (79), Expect = 0.79
Identities = 21/75 (28%), Positives = 30/75 (40%), Gaps = 4/75 (5%)
Query: 586 TSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVC---QQDGEWSGDSPTCE 642
TSC +P +P G + + F C+ G+ L G + C + W PTC
Sbjct: 1383 TSCNDPGIPQNGSRSGDSWEAGDSTVFQCDPGYALQGSAEISCVKIENRFFWQPSPPTC- 1441
Query: 643 YIDCGKLPTLPYGTM 657
CG T P G +
Sbjct: 1442 IAPCGGDLTGPSGVI 1456
Score = 35.9 bits (79), Expect = 0.79
Identities = 19/63 (30%), Positives = 28/63 (44%), Gaps = 4/63 (6%)
Query: 471 CPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTL---GGAWSGVPPSCKYV 527
C DP N S + + +AG + C+ G+ L GS ++C W PP+C
Sbjct: 1385 CNDPGIPQNGSRSGDSWEAGDSTVFQCDPGYALQGSAEISCVKIENRFFWQPSPPTC-IA 1443
Query: 528 NCG 530
CG
Sbjct: 1444 PCG 1446
Score = 35.9 bits (79), Expect = 0.79
Identities = 27/77 (35%), Positives = 32/77 (41%), Gaps = 5/77 (6%)
Query: 1 RCGHPAVPPNARVSIPNEE-NIVAGTIAVYECDEGYELFGARQRECTLRGDWTLE--PPF 57
+C P + PNA V NEE NI G I Y C G+ L G C L E PP
Sbjct: 2293 KCPPPTILPNAEVVTENEEFNI--GDIVRYRCLPGFTLVGNEILTCKLGTYLQFEGPPPI 2350
Query: 58 CGTNVAFRKPANQSTTV 74
C + + ST V
Sbjct: 2351 CEVHCPTNELLTDSTGV 2367
Score = 35.1 bits (77), Expect = 1.4
Identities = 20/63 (31%), Positives = 28/63 (44%), Gaps = 4/63 (6%)
Query: 660 LNGTTHLGSVIQYSCTTNYRLVGPVRRTC---TEEF-QWSDSSPRCEEIRCSDPIVAEKS 715
L LGS +Q++C Y L G R TC ++ F WSD P C C +
Sbjct: 355 LGSDFRLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRGPSG 414
Query: 716 IVS 718
I++
Sbjct: 415 IIT 417
Score = 35.1 bits (77), Expect = 1.4
Identities = 18/56 (32%), Positives = 27/56 (48%), Gaps = 2/56 (3%)
Query: 785 CGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPIC 840
CG+PG G+ + +G T ++C +EL G CQ+N WS + P C
Sbjct: 521 CGDPGIPAYGR--REGSRFHHGDTLKFECQPAFELVGQKAITCQKNNQWSAKKPGC 574
Score = 35.1 bits (77), Expect = 1.4
Identities = 17/57 (29%), Positives = 25/57 (43%), Gaps = 2/57 (3%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C P VP + N + G+ ++ C +GY L G+ R C W+ PP C
Sbjct: 3131 CADPGVPQFGIQN--NSQGYQVGSTVLFRCQKGYLLQGSTTRTCLPNLTWSGTPPDC 3185
Score = 34.7 bits (76), Expect = 1.8
Identities = 15/57 (26%), Positives = 26/57 (45%)
Query: 352 TCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKY 408
+CG P G+ + G + ++C L+G K+ C+K+ WS P C +
Sbjct: 520 SCGDPGIPAYGRREGSRFHHGDTLKFECQPAFELVGQKAITCQKNNQWSAKKPGCVF 576
Score = 34.7 bits (76), Expect = 1.8
Identities = 23/89 (25%), Positives = 36/89 (40%), Gaps = 5/89 (5%)
Query: 716 IVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTC----EDNG 771
++ T N R + VG+ ++G+ V Y C GY+V G S +C +
Sbjct: 1547 VIDYTENPRESCFDPGSIKNGTRVGSDLKLGSSVTYYCHGGYEVEGTSTLSCILGPDGKP 1606
Query: 772 QWSGTTPTCQYVDCGNPGRIENGKVTLPS 800
W+ P C CG +G V P+
Sbjct: 1607 VWNNPRPVCT-APCGGQYVGSDGVVLSPN 1634
Score = 34.7 bits (76), Expect = 1.8
Identities = 19/60 (31%), Positives = 26/60 (43%), Gaps = 7/60 (11%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQREC---TLRGDWTLEPPFC 58
C PAVP N + E + + ++C+ GY L G C T+R W PP C
Sbjct: 1909 CPEPAVPSNG---VKTGERYLVNDVVSFQCEPGYALQGHAHISCMPGTVR-RWNYPPPLC 1964
Score = 34.7 bits (76), Expect = 1.8
Identities = 26/102 (25%), Positives = 41/102 (40%), Gaps = 9/102 (8%)
Query: 833 WSLEPPI-CKEIT-CPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCI 890
W L+P E+ CPDP +V + ++G ++C GY L GH TC
Sbjct: 2109 WDLDPGCEAYELQECPDPEPFANG----IVRGAGYNVGQSVTFECLPGYQLTGHPVLTCQ 2164
Query: 891 --SKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSS 930
+ W+ +P C + C NG + + + SS
Sbjct: 2165 HGTNRNWDHPLPKC-EVPCGGNITSSNGTVYSPGFPSPYSSS 2205
Score = 34.3 bits (75), Expect = 2.4
Identities = 23/79 (29%), Positives = 37/79 (46%), Gaps = 9/79 (11%)
Query: 343 HWICQYLPPT----CGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKD-- 396
H++ Q +P T C S + LG+D+ VG+ + ++C G+ L G C
Sbjct: 1721 HFVYQAVPRTSATQCSSVPEPRYGKRLGSDFSVGAIVRFECNSGYALQGSPEIECLPVPG 1780
Query: 397 --GFWSGAPPSCKYVNCGG 413
W+ + P+C V CGG
Sbjct: 1781 ALAQWNVSAPTC-VVPCGG 1798
Score = 34.3 bits (75), Expect = 2.4
Identities = 21/65 (32%), Positives = 32/65 (49%), Gaps = 12/65 (18%)
Query: 844 TCPDPSAQ---IKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCI--SKGQWNGT 898
+CP+P+ +K G LV +QCE GY L+GH +C+ + +WN
Sbjct: 1908 SCPEPAVPSNGVKTGERYLV-------NDVVSFQCEPGYALQGHAHISCMPGTVRRWNYP 1960
Query: 899 VPVCI 903
P+CI
Sbjct: 1961 PPLCI 1965
Score = 34.3 bits (75), Expect = 2.4
Identities = 24/61 (39%), Positives = 27/61 (44%), Gaps = 7/61 (11%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYEL-FGAR-QRECTLRGDWTLE--PPF 57
CG P P N V + GT A+Y C EGY L GA EC G W+ PP
Sbjct: 2531 CGLPEAPKNGMVF---GKEYTVGTKAMYSCSEGYHLQAGAEATAECLDTGLWSNRNVPPQ 2587
Query: 58 C 58
C
Sbjct: 2588 C 2588
Score = 33.9 bits (74), Expect = 3.2
Identities = 14/42 (33%), Positives = 19/42 (45%)
Query: 427 NRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLF 468
+R HG + C+ F LVG TC W + P C+F
Sbjct: 535 SRFHHGDTLKFECQPAFELVGQKAITCQKNNQWSAKKPGCVF 576
Score = 33.9 bits (74), Expect = 3.2
Identities = 20/66 (30%), Positives = 32/66 (48%), Gaps = 8/66 (12%)
Query: 863 STLSIGGEAHYQCERGYNLKGHQTRTCI----SKGQWNGTVPVCIPIDCRSPGNI-ENGK 917
S S+G ++C GY L+G C+ + QWN + P C+ + C GN+ E
Sbjct: 1749 SDFSVGAIVRFECNSGYALQGSPEIECLPVPGALAQWNVSAPTCV-VPC--GGNLTERRG 1805
Query: 918 IVISNG 923
++S G
Sbjct: 1806 TILSPG 1811
Score = 33.5 bits (73), Expect = 4.2
Identities = 15/47 (31%), Positives = 25/47 (53%), Gaps = 1/47 (2%)
Query: 863 STLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRS 909
ST ++G + Y C G+ L+GH TC + + + T +P CR+
Sbjct: 153 STFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLP-SCRA 198
Score = 33.1 bits (72), Expect = 5.6
Identities = 19/70 (27%), Positives = 28/70 (40%), Gaps = 4/70 (5%)
Query: 549 GSIAQFTCEPDYWLNGAEELVC----NRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFDY 604
GS QFTC Y L G++ + C + WS P C C G + + ++
Sbjct: 362 GSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRGPSGIITSPNF 421
Query: 605 YVHSTINFHC 614
+ N HC
Sbjct: 422 PIQYDNNAHC 431
Score = 32.7 bits (71), Expect = 7.4
Identities = 15/57 (26%), Positives = 22/57 (38%), Gaps = 3/57 (5%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C P +P N + + + G + + CD GY L EC W+ P C
Sbjct: 867 CLDPGIPVNGQ---RHGNDFYVGALVTFSCDSGYTLSDGEPLECEPNFQWSRALPSC 920
Score = 32.7 bits (71), Expect = 7.4
Identities = 19/57 (33%), Positives = 25/57 (43%), Gaps = 3/57 (5%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C P + PN +V + + G+ Y C EGY+L C G WT E P C
Sbjct: 3012 CKPPPLIPNGKVV---GSDFMWGSSVTYACLEGYQLSLPAVFTCEGNGSWTGELPQC 3065
Score = 32.3 bits (70), Expect = 9.7
Identities = 20/67 (29%), Positives = 28/67 (41%), Gaps = 2/67 (2%)
Query: 777 TPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLE 836
T T Q C +PG NG+ N + GA + CD + L C+ N WS
Sbjct: 859 TITLQSDHCLDPGIPVNGQ--RHGNDFYVGALVTFSCDSGYTLSDGEPLECEPNFQWSRA 916
Query: 837 PPICKEI 843
P C+ +
Sbjct: 917 LPSCEAL 923
Score = 32.3 bits (70), Expect = 9.7
Identities = 11/38 (28%), Positives = 21/38 (55%), Gaps = 2/38 (5%)
Query: 868 GGEAHYQCERGYNLKGHQTRTCIS--KGQWNGTVPVCI 903
G + C+ GY+L+G + C+S + W+ +P C+
Sbjct: 1231 GSSVSFSCDPGYSLRGSEELLCLSGERRTWDRPLPTCV 1268
>BX538049-1|CAD97988.1| 1323|Homo sapiens hypothetical protein
protein.
Length = 1323
Score = 309 bits (759), Expect = 3e-83
Identities = 186/641 (29%), Positives = 282/641 (43%), Gaps = 41/641 (6%)
Query: 349 LPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWS-GAPPSCK 407
+P CG P + N + G +++VGS++ + C EG+ L+G S C+K G W+ + P C
Sbjct: 12 VPLDCGKPPPIQNGFMKGENFEVGSKVQFFCNEGYELVGGSSWTCQKSGKWNKKSNPKCM 71
Query: 408 YVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL 467
C P+ + + L + T G +SC+E L G C W+ P C
Sbjct: 72 PAKCPE-PPLLENQLVLKELTTEVGV-VTFSCKEGHVLQGPSVLKCLPSQQWNDSFPVCK 129
Query: 468 FDWCPDPPAVS-NASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKY 526
C PP +S + + GS Y+C G L G+++ C G WS P C
Sbjct: 130 IVLCTPPPLISFGVPIPSSALHFGSTVKYSCVGGFFLRGNSTTLCQPDGTWSSPLPECVP 189
Query: 527 VNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELT 586
V C P + + G Y S A +TC+P + L G +C +G W P+C+
Sbjct: 190 VECPQPEEIPNGIIDVQG-LAYLSTALYTCKPGFELVGNTTTLCGENGHWLGGKPTCKAI 248
Query: 587 SCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDC 646
C +P+ G D + T+ + C G +L G L C + G+W D+P+C I C
Sbjct: 249 ECLKPKEILNGKFSYTDLHYGQTVTYSCNRGFRLEGPSALTCLETGDWDVDAPSCNAIHC 308
Query: 647 GKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRC 706
+ G +E G++I YSC +++ G +TC EE WS S P C I C
Sbjct: 309 DSPQPIENGFVE--GADYSYGAIIIYSCFPGFQVAGHAMQTC-EESGWSSSIPTCMPIDC 365
Query: 707 SDP-----------------IVAEKSIVS---VTGNDRSHGHTLIRTSDNRDV-----GN 741
P E ++ VT + H + +T +N +
Sbjct: 366 GLPPHIDFGDCTKLKDDQGYFEQEDDMMEVPYVTPHPPYHLGAVAKTWENTKESPATHSS 425
Query: 742 TYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSN 801
+ G +V Y C GY+++G + C+++G W+G+ P+C ++C P ENG L
Sbjct: 426 NFLYGTMVSYTCNPGYELLGNPVLICQEDGTWNGSAPSCISIECDLPTAPENG--FLRFT 483
Query: 802 ATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVV 861
T G+ Y C L G R+C EN WS P C+ I+C P+ + GS +
Sbjct: 484 ETSMGSAVQYSCKPGHILAGSDLRLCLENRKWSGASPRCEAISCKKPN-PVMNGS---IK 539
Query: 862 TSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVIS 921
S + +Y+C+ GY L G + RTC W+ P+CIP+DC SP NG+ +
Sbjct: 540 GSNYTYLSTLYYECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDCSSPPVSANGQ--VR 597
Query: 922 NGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
F +EY C + G R CL +G WSG P C
Sbjct: 598 GDEYTFQKEIEYTCNEGFLLEGARSRVCLANGSWSGATPDC 638
Score = 296 bits (726), Expect = 3e-79
Identities = 186/614 (30%), Positives = 267/614 (43%), Gaps = 36/614 (5%)
Query: 352 TCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNC 411
+C P+ ++N +I G++Y S + Y+C G++L G + R C+ D W P C V+C
Sbjct: 526 SCKKPNPVMNGSIKGSNYTYLSTLYYECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDC 585
Query: 412 GGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWC 471
+G V + T Y+C E F L G R C G W G P C+ C
Sbjct: 586 SSPPVSANGQVR--GDEYTFQKEIEYTCNEGFLLEGARSRVCLANGSWSGATPDCVPVRC 643
Query: 472 PDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGT 531
PP ++N + ++ C G+IL G+ +TC G W P CK VNCG
Sbjct: 644 ATPPQLANGVTEGLDYGFMKEVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCKPVNCGP 703
Query: 532 PTIHKGSFVLING-TTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPE 590
P F NG + +G Q+ C P Y L+G C +G WS PSC C
Sbjct: 704 PEDLAHGFP--NGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCLPCRCST 761
Query: 591 PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLP 650
P V G + D+ C G KL+G + C+ DG+WS P CE+ CG LP
Sbjct: 762 P-VIEYGTVNGTDFDCGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHCEHTSCGSLP 820
Query: 651 TLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPI 710
+P + ++ +VI YSC + Y + G CTE+ WS P CE + C P
Sbjct: 821 MIPNAFIS--ETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPLSCGSP- 877
Query: 711 VAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGES-LSTCED 769
S+ + +H TY + VK RC +GY + ++ TC+
Sbjct: 878 ---PSVANAVATGEAH---------------TYE--SEVKLRCLEGYTMDTDTDTFTCQK 917
Query: 770 NGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQE 829
+G+W +C C P I + + + + C E + EGV +CQ
Sbjct: 918 DGRWFPERISCSPKKCPLPESITH--ILVHGDDFSVNRQVSVSCAEGYTFEGVNISVCQL 975
Query: 830 NGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTC 889
+GTW EPP E P + ++ VV S + YQCE GY L+G++ R C
Sbjct: 976 DGTW--EPPFSDESCSPVSCGKPESPEHGFVVGSKYTFESTIIYQCEPGYELEGNRERVC 1033
Query: 890 ISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKC 949
QW+G V +C C +P NGK I N +T G +V Y C Y GP C
Sbjct: 1034 QENRQWSGGVAICKETRCETPLEFLNGKADIENRTT--GPNVVYSCNRGYSLEGPSEAHC 1091
Query: 950 LDDGRWSGEEPSCE 963
++G WS P C+
Sbjct: 1092 TENGTWSHPVPLCK 1105
Score = 293 bits (720), Expect = 2e-78
Identities = 180/620 (29%), Positives = 269/620 (43%), Gaps = 50/620 (8%)
Query: 353 CGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCG 412
C P N + + +GS + Y C GH+L G R C ++ WSGA P C+ ++C
Sbjct: 469 CDLPTAPENGFLRFTETSMGSAVQYSCKPGHILAGSDLRLCLENRKWSGASPRCEAISCK 528
Query: 413 GLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCP 472
P+ +G + + T+ + Y C + L G RTC D+ WD + P C+ C
Sbjct: 529 KPNPVMNGSIK--GSNYTYLSTLYYECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDCS 586
Query: 473 DPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTP 532
PP +N V + + YTC G +L G+ S C G+WSG P C V C TP
Sbjct: 587 SPPVSANGQVRGDEYTFQKEIEYTCNEGFLLEGARSRVCLANGSWSGATPDCVPVRCATP 646
Query: 533 TIHKGSFVLINGTT---TYGSIAQ--FTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTS 587
L NG T YG + + F C Y L+GA +L C DG W +IP C+ +
Sbjct: 647 P------QLANGVTEGLDYGFMKEVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCKPVN 700
Query: 588 CPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCG 647
C PE + G+ F + I + C G+KL G + C +G WSG SP+C C
Sbjct: 701 CGPPEDLAHGFPNGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCLPCRC- 759
Query: 648 KLPTLPYGTMELLNGTT-HLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRC 706
P + YGT +NGT G + C ++L+G TC + QWS P CE C
Sbjct: 760 STPVIEYGT---VNGTDFDCGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHCEHTSC 816
Query: 707 SDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLST 766
+ + +S T + + + ++ Y C GY + G S
Sbjct: 817 GSLPMIPNAFISETSSWKEN---------------------VITYSCRSGYVIQGSSDLI 855
Query: 767 CEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELE-GVIRR 825
C + G WS P C+ + CG+P + N T A Y + +C E + ++
Sbjct: 856 CTEKGVWSQPYPVCEPLSCGSPPSVANAVAT--GEAHTYESEVKLRCLEGYTMDTDTDTF 913
Query: 826 MCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQ 885
CQ++G W E C CP P ++ + +LV S+ + C GY +G
Sbjct: 914 TCQKDGRWFPERISCSPKKCPLP----ESITHILVHGDDFSVNRQVSVSCAEGYTFEGVN 969
Query: 886 TRTCISKGQWNG--TVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVG 943
C G W + C P+ C P + E+G +V S + F S++ Y C Y+ G
Sbjct: 970 ISVCQLDGTWEPPFSDESCSPVSCGKPESPEHGFVVGSKYT--FESTIIYQCEPGYELEG 1027
Query: 944 PFLRKCLDDGRWSGEEPSCE 963
R C ++ +WSG C+
Sbjct: 1028 NRERVCQENRQWSGGVAICK 1047
Score = 289 bits (709), Expect = 4e-77
Identities = 175/586 (29%), Positives = 255/586 (43%), Gaps = 38/586 (6%)
Query: 372 GSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRTTH 431
G+ + Y C G+ LLG+ C++DG W+G+ PSC + C T E+G + + T+
Sbjct: 430 GTMVSYTCNPGYELLGNPVLICQEDGTWNGSAPSCISIECDLPTAPENGFLRFTE--TSM 487
Query: 432 GARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGS 491
G+ YSC+ L G+ R C + W G +PRC C P V N S+ + + S
Sbjct: 488 GSAVQYSCKPGHILAGSDLRLCLENRKWSGASPRCEAISCKKPNPVMNGSIKGSNYTYLS 547
Query: 492 LASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTIHKGSFVLINGTTTYGSI 551
Y C+ G++L+G+ TC W P C V+C +P + V T+
Sbjct: 548 TLYYECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDCSSPPVSANGQVR-GDEYTFQKE 606
Query: 552 AQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFDYYVHSTIN 611
++TC + L GA VC +G WS P C C P + G E DY +
Sbjct: 607 IEYTCNEGFLLEGARSRVCLANGSWSGATPDCVPVRCATPPQLANGVTEGLDYGFMKEVT 666
Query: 612 FHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHL-GSVI 670
FHC G+ L G P L CQ DG W + P C+ ++CG L +G NG + + G I
Sbjct: 667 FHCHEGYILHGAPKLTCQSDGNWDAEIPLCKPVNCGPPEDLAHG---FPNGFSFIHGGHI 723
Query: 671 QYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTL 730
QY C Y+L G R C WS SSP C RCS P++ +V G D
Sbjct: 724 QYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCLPCRCSTPVI---EYGTVNGTD------- 773
Query: 731 IRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGR 790
D G RI +C KG+K++G S TCE +GQWS P C++ CG+
Sbjct: 774 ------FDCGKAARI------QCFKGFKLLGLSEITCEADGQWSSGFPHCEHTSCGSLPM 821
Query: 791 IENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSA 850
I N ++ +++ Y C + ++G +C E G WS P+C+ ++C P +
Sbjct: 822 IPNAFIS--ETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPLSCGSPPS 879
Query: 851 QIKAGSGLLVVTSTLSIGGEAHYQCERGYNL-KGHQTRTCISKGQWNGTVPVCIPIDCRS 909
A + + E +C GY + T TC G+W C P C
Sbjct: 880 VANA----VATGEAHTYESEVKLRCLEGYTMDTDTDTFTCQKDGRWFPERISCSPKKCPL 935
Query: 910 PGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRW 955
P +I + I++ V C Y G + C DG W
Sbjct: 936 PESITH--ILVHGDDFSVNRQVSVSCAEGYTFEGVNISVCQLDGTW 979
Score = 287 bits (704), Expect = 1e-76
Identities = 184/621 (29%), Positives = 267/621 (42%), Gaps = 43/621 (6%)
Query: 349 LPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKY 408
+P C SP N + G++Y I Y C EG +L G +SR C +G WSGA P C
Sbjct: 581 IPVDCSSPPVSANGQVRGDEYTFQKEIEYTCNEGFLLEGARSRVCLANGSWSGATPDCVP 640
Query: 409 VNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLF 468
V C + +G +D + C E + L G P+ TC +G WD E P C
Sbjct: 641 VRCATPPQLANGVTEGLDYGFMK--EVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCKP 698
Query: 469 DWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVN 528
C P +++ G Y C G+ L G++S C G+WSG PSC
Sbjct: 699 VNCGPPEDLAHGFPNGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCLPCR 758
Query: 529 CGTPTIHKGSFVLINGTT-TYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTS 587
C TP I G+ +NGT G A+ C + L G E+ C DG+WS P CE TS
Sbjct: 759 CSTPVIEYGT---VNGTDFDCGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHCEHTS 815
Query: 588 CPE-PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDC 646
C P +P+ ++ + + I + C +G+ + G +L+C + G WS P CE + C
Sbjct: 816 CGSLPMIPN-AFISETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPLSC 874
Query: 647 GKLPTLPYGTMELLNGTTH-LGSVIQYSCTTNYRL-VGPVRRTCTEEFQWSDSSPRCEEI 704
G P++ + G H S ++ C Y + TC ++ +W C
Sbjct: 875 GSPPSV---ANAVATGEAHTYESEVKLRCLEGYTMDTDTDTFTCQKDGRWFPERISCSPK 931
Query: 705 RCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESL 764
+C P S+T H L+ G+ + + V C +GY G ++
Sbjct: 932 KCPLP-------ESIT-------HILVH-------GDDFSVNRQVSVSCAEGYTFEGVNI 970
Query: 765 STCEDNGQWSG--TTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGV 822
S C+ +G W + +C V CG P E+G V + S TF +T YQC+ +ELEG
Sbjct: 971 SVCQLDGTWEPPFSDESCSPVSCGKPESPEHGFV-VGSKYTF-ESTIIYQCEPGYELEGN 1028
Query: 823 IRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLK 882
R+CQEN WS ICKE C P + + + + G Y C RGY+L+
Sbjct: 1029 RERVCQENRQWSGGVAICKETRCETPLEFLNGKADI----ENRTTGPNVVYSCNRGYSLE 1084
Query: 883 GHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRV 942
G C G W+ VP+C P C P I + +S +V C +
Sbjct: 1085 GPSEAHCTENGTWSHPVPLCKPNPCPVPFVIPENAL-LSEKEFYVDQNVSIKCREGFLLQ 1143
Query: 943 GPFLRKCLDDGRWSGEEPSCE 963
G + C D W+ CE
Sbjct: 1144 GHGIITCNPDETWTQTSAKCE 1164
Score = 280 bits (687), Expect = 2e-74
Identities = 167/565 (29%), Positives = 249/565 (44%), Gaps = 47/565 (8%)
Query: 400 SGAPPSCKYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIW 459
S +P C ++CG PI++G + G++ + C E + LVG TC G W
Sbjct: 5 SESPLMCVPLDCGKPPPIQNGFMK--GENFEVGSKVQFFCNEGYELVGGSSWTCQKSGKW 62
Query: 460 DGEA-PRCLFDWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWS 518
+ ++ P+C+ CP+PP + N V + +++C+ GH+L G + + C W+
Sbjct: 63 NKKSNPKCMPAKCPEPPLLENQLVLKELTTEVGVVTFSCKEGHVLQGPSVLKCLPSQQWN 122
Query: 519 GVPPSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSY 578
P CK V C P + + + +GS +++C ++L G +C DG WS
Sbjct: 123 DSFPVCKIVLCTPPPLISFGVPIPSSALHFGSTVKYSCVGGFFLRGNSTTLCQPDGTWSS 182
Query: 579 DIPSCELTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDS 638
+P C CP+PE G ++ ST + C+ G +L+G +C ++G W G
Sbjct: 183 PLPECVPVECPQPEEIPNGIIDVQGLAYLSTALYTCKPGFELVGNTTTLCGENGHWLGGK 242
Query: 639 PTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSS 698
PTC+ I+C K + G + H G + YSC +RL GP TC E W +
Sbjct: 243 PTCKAIECLKPKEILNGKFSYTD--LHYGQTVTYSCNRGFRLEGPSALTCLETGDWDVDA 300
Query: 699 PRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYK 758
P C I C P E V G Y GA++ Y C G++
Sbjct: 301 PSCNAIHCDSPQPIENGFVE---------------------GADYSYGAIIIYSCFPGFQ 339
Query: 759 VIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWE 818
V G ++ TCE++G WS + PTC +DCG P I+ G T + Y F Q D+ E
Sbjct: 340 VAGHAMQTCEESG-WSSSIPTCMPIDCGLPPHIDFGDCTKLKDDQGY----FEQEDDMME 394
Query: 819 LEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERG 878
+ V G + KE P+ +S G Y C G
Sbjct: 395 VPYVTPHPPYHLGAVAKTWENTKE----SPATH----------SSNFLYGTMVSYTCNPG 440
Query: 879 YNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQ 938
Y L G+ C G WNG+ P CI I+C P ENG + + T GS+V+Y C
Sbjct: 441 YELLGNPVLICQEDGTWNGSAPSCISIECDLPTAPENGFLRFT--ETSMGSAVQYSCKPG 498
Query: 939 YQRVGPFLRKCLDDGRWSGEEPSCE 963
+ G LR CL++ +WSG P CE
Sbjct: 499 HILAGSDLRLCLENRKWSGASPRCE 523
Score = 274 bits (671), Expect = 1e-72
Identities = 176/621 (28%), Positives = 253/621 (40%), Gaps = 46/621 (7%)
Query: 349 LPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKY 408
+P C +P +L N G DY + + C EG++L G C+ DG W P CK
Sbjct: 639 VPVRCATPPQLANGVTEGLDYGFMKEVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCKP 698
Query: 409 VNCGGLTPIEDGDVALIDNRT-THGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL 467
VNCG P ED + + HG Y C + L GN R C G W G +P CL
Sbjct: 699 VNCG---PPEDLAHGFPNGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCL 755
Query: 468 FDWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYV 527
C P + +V G A C G L G + +TC G WS P C++
Sbjct: 756 PCRC-STPVIEYGTVNGTDFDCGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHCEHT 814
Query: 528 NCGTPTIHKGSFVLINGTTTYG-SIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELT 586
+CG+ + +F I+ T+++ ++ ++C Y + G+ +L+C G WS P CE
Sbjct: 815 SCGSLPMIPNAF--ISETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPL 872
Query: 587 SCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPN-LVCQQDGEWSGDSPTCEYID 645
SC P + + S + C G+ + + + CQ+DG W + +C
Sbjct: 873 SCGSPPSVANAVATGEAHTYESEVKLRCLEGYTMDTDTDTFTCQKDGRWFPERISCSPKK 932
Query: 646 CGKLPTLPYGTMELLNGTTH-LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSD--SSPRCE 702
C P T L++G + + SC Y G C + W S C
Sbjct: 933 C---PLPESITHILVHGDDFSVNRQVSVSCAEGYTFEGVNISVCQLDGTWEPPFSDESCS 989
Query: 703 EIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGE 762
+ C P E HG VG+ Y + + Y+CE GY++ G
Sbjct: 990 PVSCGKPESPE------------HGFV---------VGSKYTFESTIIYQCEPGYELEGN 1028
Query: 763 SLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGV 822
C++N QWSG C+ C P NGK + + T G Y C+ + LEG
Sbjct: 1029 RERVCQENRQWSGGVAICKETRCETPLEFLNGKADIENRTT--GPNVVYSCNRGYSLEGP 1086
Query: 823 IRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLK 882
C ENGTWS P+CK CP P L+ + +C G+ L+
Sbjct: 1087 SEAHCTENGTWSHPVPLCKPNPCPVP---FVIPENALLSEKEFYVDQNVSIKCREGFLLQ 1143
Query: 883 GHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRV 942
GH TC W T C I C P ++EN + +G + Y C S Y
Sbjct: 1144 GHGIITCNPDETWTQTSAKCEKISCGPPAHVENA--IARGVHYQYGDMITYSCYSGYMLE 1201
Query: 943 GPFLRK-CLDDGRWSGEEPSC 962
G FLR CL++G W+ P C
Sbjct: 1202 G-FLRSVCLENGTWT-SPPIC 1220
Score = 266 bits (651), Expect = 4e-70
Identities = 165/537 (30%), Positives = 232/537 (43%), Gaps = 42/537 (7%)
Query: 431 HGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAG 490
+G Y+C + L+GNP C ++G W+G AP C+ C P A N + G
Sbjct: 429 YGTMVSYTCNPGYELLGNPVLICQEDGTWNGSAPSCISIECDLPTAPENGFLRFTETSMG 488
Query: 491 SLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPT-IHKGSFVLINGTT-TY 548
S Y+C+ GHIL+GS C WSG P C+ ++C P + GS I G+ TY
Sbjct: 489 SAVQYSCKPGHILAGSDLRLCLENRKWSGASPRCEAISCKKPNPVMNGS---IKGSNYTY 545
Query: 549 GSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFDYYVHS 608
S + C+P Y LNG E C D W D P C C P V + G + +Y
Sbjct: 546 LSTLYYECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDCSSPPVSANGQVRGDEYTFQK 605
Query: 609 TINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGS 668
I + C G L G + VC +G WSG +P C + C P L G E L+
Sbjct: 606 EIEYTCNEGFLLEGARSRVCLANGSWSGATPDCVPVRCATPPQLANGVTEGLD--YGFMK 663
Query: 669 VIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGH 728
+ + C Y L G + TC + W P C+ + C P D +HG
Sbjct: 664 EVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCKPVNCGPP------------EDLAHGF 711
Query: 729 TLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNP 788
G ++ G ++Y+C GYK+ G S C NG WSG++P+C C P
Sbjct: 712 ---------PNGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCLPCRCSTP 762
Query: 789 GRIENGKVTLPSNATFY--GATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCP 846
IE G V N T + G A QC + ++L G+ C+ +G WS P C+ +C
Sbjct: 763 -VIEYGTV----NGTDFDCGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHCEHTSC- 816
Query: 847 DPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPID 906
+ + + TS+ Y C GY ++G C KG W+ PVC P+
Sbjct: 817 --GSLPMIPNAFISETSSWK-ENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPLS 873
Query: 907 CRSPGNIENGKIVISNGSTLFGSSVEYYCLSQY-QRVGPFLRKCLDDGRWSGEEPSC 962
C SP ++ N V + + + S V+ CL Y C DGRW E SC
Sbjct: 874 CGSPPSVANA--VATGEAHTYESEVKLRCLEGYTMDTDTDTFTCQKDGRWFPERISC 928
Score = 167 bits (405), Expect = 2e-40
Identities = 124/483 (25%), Positives = 192/483 (39%), Gaps = 49/483 (10%)
Query: 352 TCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNC 411
+CGS + N I + I Y C G+++ G C + G WS P C+ ++C
Sbjct: 815 SCGSLPMIPNAFISETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPLSC 874
Query: 412 GGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPER-TCGDEGIWDGEAPRCLFDW 470
G +P + T+ + C E +T+ + + TC +G W E C
Sbjct: 875 G--SPPSVANAVATGEAHTYESEVKLRCLEGYTMDTDTDTFTCQKDGRWFPERISCSPKK 932
Query: 471 CPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPP----SCKY 526
CP P ++++ V + S +C G+ G C L G W PP SC
Sbjct: 933 CPLPESITHILVHGDDFSVNRQVSVSCAEGYTFEGVNISVCQLDGTWE--PPFSDESCSP 990
Query: 527 VNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELT 586
V+CG P + FV + T+ S + CEP Y L G E VC + +WS + C+ T
Sbjct: 991 VSCGKPESPEHGFV-VGSKYTFESTIIYQCEPGYELEGNRERVCQENRQWSGGVAICKET 1049
Query: 587 SCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDC 646
C P G + + + + C G+ L G C ++G WS P C+ C
Sbjct: 1050 RCETPLEFLNGKADIENRTTGPNVVYSCNRGYSLEGPSEAHCTENGTWSHPVPLCKPNPC 1109
Query: 647 GKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRC 706
+P + L ++ + C + L G TC + W+ +S +CE+I C
Sbjct: 1110 PVPFVIPENAL-LSEKEFYVDQNVSIKCREGFLLQGHGIITCNPDETWTQTSAKCEKISC 1168
Query: 707 SDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLST 766
P E +I G Y+ G ++ Y C GY + G S
Sbjct: 1169 GPPAHVENAIAR---------------------GVHYQYGDMITYSCYSGYMLEGFLRSV 1207
Query: 767 CEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRM 826
C +NG W+ + P C+ V C P +NG + NA C E W + R+
Sbjct: 1208 CLENGTWT-SPPICRAV-CRFP--CQNGGICQRPNAC--------SCPEGW-----MGRL 1250
Query: 827 CQE 829
C+E
Sbjct: 1251 CEE 1253
Score = 153 bits (371), Expect = 3e-36
Identities = 103/369 (27%), Positives = 145/369 (39%), Gaps = 13/369 (3%)
Query: 345 ICQYLPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRH-CKKDGFWSGAP 403
+C+ P +CGSP + N G + S + +C EG+ + D C+KDG W
Sbjct: 868 VCE--PLSCGSPPSVANAVATGEAHTYESEVKLRCLEGYTMDTDTDTFTCQKDGRWFPER 925
Query: 404 PSCKYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDG-- 461
SC C P + + + + + SC E +T G C +G W+
Sbjct: 926 ISCSPKKCP--LPESITHILVHGDDFSVNRQVSVSCAEGYTFEGVNISVCQLDGTWEPPF 983
Query: 462 EAPRCLFDWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVP 521
C C P + + V + + S Y CE G+ L G+ C WSG
Sbjct: 984 SDESCSPVSCGKPESPEHGFVVGSKYTFESTIIYQCEPGYELEGNRERVCQENRQWSGGV 1043
Query: 522 PSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIP 581
CK C TP I TT G ++C Y L G E C +G WS+ +P
Sbjct: 1044 AICKETRCETPLEFLNGKADIENRTT-GPNVVYSCNRGYSLEGPSEAHCTENGTWSHPVP 1102
Query: 582 SCELTSCPEPEV-PSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPT 640
C+ CP P V P + ++YV ++ C G L G + C D W+ S
Sbjct: 1103 LCKPNPCPVPFVIPENALLSEKEFYVDQNVSIKCREGFLLQGHGIITCNPDETWTQTSAK 1162
Query: 641 CEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPR 700
CE I CG P G +I YSC + Y L G +R C E W+ S P
Sbjct: 1163 CEKISCG--PPAHVENAIARGVHYQYGDMITYSCYSGYMLEGFLRSVCLENGTWT-SPPI 1219
Query: 701 CEEIRCSDP 709
C + C P
Sbjct: 1220 CRAV-CRFP 1227
Score = 97.5 bits (232), Expect = 2e-19
Identities = 58/192 (30%), Positives = 87/192 (45%), Gaps = 9/192 (4%)
Query: 773 WSGTTPT-CQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENG 831
W +P C +DCG P I+NG + G+ + C+E +EL G CQ++G
Sbjct: 3 WHSESPLMCVPLDCGKPPPIQNG--FMKGENFEVGSKVQFFCNEGYELVGGSSWTCQKSG 60
Query: 832 TWSLEP-PICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCI 890
W+ + P C CP+P LV+ + G + C+ G+ L+G C+
Sbjct: 61 KWNKKSNPKCMPAKCPEPPLL----ENQLVLKELTTEVGVVTFSCKEGHVLQGPSVLKCL 116
Query: 891 SKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCL 950
QWN + PVC + C P I G + I + + FGS+V+Y C+ + G C
Sbjct: 117 PSQQWNDSFPVCKIVLCTPPPLISFG-VPIPSSALHFGSTVKYSCVGGFFLRGNSTTLCQ 175
Query: 951 DDGRWSGEEPSC 962
DG WS P C
Sbjct: 176 PDGTWSSPLPEC 187
Score = 64.9 bits (151), Expect = 1e-09
Identities = 39/134 (29%), Positives = 62/134 (46%), Gaps = 8/134 (5%)
Query: 833 WSLEPPI-CKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCIS 891
W E P+ C + C P I+ G + +G + + C GY L G + TC
Sbjct: 3 WHSESPLMCVPLDCGKPPP-IQNG---FMKGENFEVGSKVQFFCNEGYELVGGSSWTCQK 58
Query: 892 KGQWNG-TVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCL 950
G+WN + P C+P C P +EN ++V+ +T G V + C + GP + KCL
Sbjct: 59 SGKWNKKSNPKCMPAKCPEPPLLEN-QLVLKELTTEVGV-VTFSCKEGHVLQGPSVLKCL 116
Query: 951 DDGRWSGEEPSCEL 964
+W+ P C++
Sbjct: 117 PSQQWNDSFPVCKI 130
Score = 42.3 bits (95), Expect = 0.009
Identities = 22/61 (36%), Positives = 26/61 (42%), Gaps = 3/61 (4%)
Query: 1 RCGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGT 60
RC P N + I EN G VY C+ GY L G + CT G W+ P C
Sbjct: 1050 RCETPLEFLNGKADI---ENRTTGPNVVYSCNRGYSLEGPSEAHCTENGTWSHPVPLCKP 1106
Query: 61 N 61
N
Sbjct: 1107 N 1107
Score = 37.5 bits (83), Expect = 0.26
Identities = 23/77 (29%), Positives = 29/77 (37%), Gaps = 7/77 (9%)
Query: 8 PPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTNVAFRKP 67
P + PN + + G Y+C GY+L G R C G W+ P C P
Sbjct: 704 PEDLAHGFPNGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSC-------LP 756
Query: 68 ANQSTTVRGGAAANGND 84
ST V NG D
Sbjct: 757 CRCSTPVIEYGTVNGTD 773
Score = 37.1 bits (82), Expect = 0.34
Identities = 21/57 (36%), Positives = 26/57 (45%), Gaps = 3/57 (5%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C P V N +V +E I Y C+EG+ L GAR R C G W+ P C
Sbjct: 585 CSSPPVSANGQVR--GDEYTFQKEIE-YTCNEGFLLEGARSRVCLANGSWSGATPDC 638
Score = 35.9 bits (79), Expect = 0.79
Identities = 17/48 (35%), Positives = 22/48 (45%)
Query: 29 YECDEGYELFGARQRECTLRGDWTLEPPFCGTNVAFRKPANQSTTVRG 76
YECD GY L G +R C +W + P C P + + VRG
Sbjct: 551 YECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDCSSPPVSANGQVRG 598
Score = 34.7 bits (76), Expect = 1.8
Identities = 15/42 (35%), Positives = 19/42 (45%)
Query: 17 NEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
+ N + GT+ Y C+ GYEL G C G W P C
Sbjct: 423 HSSNFLYGTMVSYTCNPGYELLGNPVLICQEDGTWNGSAPSC 464
Score = 34.7 bits (76), Expect = 1.8
Identities = 21/57 (36%), Positives = 24/57 (42%), Gaps = 4/57 (7%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
CG PA NA I + G + Y C GY L G + C G WT PP C
Sbjct: 1168 CGPPAHVENA---IARGVHYQYGDMITYSCYSGYMLEGFLRSVCLENGTWT-SPPIC 1220
Score = 34.3 bits (75), Expect = 2.4
Identities = 18/57 (31%), Positives = 26/57 (45%), Gaps = 3/57 (5%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
CG + PNA +S E + + Y C GY + G+ CT +G W+ P C
Sbjct: 816 CGSLPMIPNAFIS---ETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVC 869
Score = 34.3 bits (75), Expect = 2.4
Identities = 18/51 (35%), Positives = 25/51 (49%), Gaps = 3/51 (5%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWT 52
CG P P + V + TI +Y+C+ GYEL G R+R C W+
Sbjct: 993 CGKPESPEHGFVV--GSKYTFESTI-IYQCEPGYELEGNRERVCQENRQWS 1040
Score = 33.9 bits (74), Expect = 3.2
Identities = 15/44 (34%), Positives = 19/44 (43%)
Query: 8 PPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDW 51
PP + EN G+ + C+EGYEL G C G W
Sbjct: 19 PPPIQNGFMKGENFEVGSKVQFFCNEGYELVGGSSWTCQKSGKW 62
Score = 33.5 bits (73), Expect = 4.2
Identities = 12/35 (34%), Positives = 16/35 (45%)
Query: 24 GTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
G Y C+ G+ L G C GDW ++ P C
Sbjct: 269 GQTVTYSCNRGFRLEGPSALTCLETGDWDVDAPSC 303
Score = 33.5 bits (73), Expect = 4.2
Identities = 13/30 (43%), Positives = 16/30 (53%)
Query: 29 YECDEGYELFGARQRECTLRGDWTLEPPFC 58
+ C EGY L GA + C G+W E P C
Sbjct: 667 FHCHEGYILHGAPKLTCQSDGNWDAEIPLC 696
>BX537918-1|CAD97901.1| 1441|Homo sapiens hypothetical protein
protein.
Length = 1441
Score = 308 bits (755), Expect = 1e-82
Identities = 185/641 (28%), Positives = 282/641 (43%), Gaps = 41/641 (6%)
Query: 349 LPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSG-APPSCK 407
+P CG P + N + G +++VGS++ + C EG+ L+GD S C+K G W+ + P C
Sbjct: 130 VPLDCGKPPPIQNGFMKGENFEVGSKVQFFCNEGYELVGDSSWTCQKSGKWNKKSNPKCM 189
Query: 408 YVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL 467
C P+ + + L + T G +SC+E L G C W+ P C
Sbjct: 190 PAKCPE-PPLLENQLVLKELTTEVGV-VTFSCKEGHVLQGPSVLKCLPSQQWNDSFPVCK 247
Query: 468 FDWCPDPPAVS-NASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKY 526
C PP +S + + GS Y+C G L G+++ C G WS P C
Sbjct: 248 IVLCTPPPLISFGVPIPSSALHFGSTVKYSCVGGFFLRGNSTTLCQPDGTWSSPLPECVP 307
Query: 527 VNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELT 586
V C P + + G Y S A +TC+P + L G +C +G W P+C+
Sbjct: 308 VECPQPEEIPNGIIDVQGLA-YLSTALYTCKPGFELVGNTTTLCGENGHWLGGKPTCKAI 366
Query: 587 SCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDC 646
C +P+ G D + + + C G +L G L C + G+W D+P+C I C
Sbjct: 367 ECLKPKEILNGKFSYTDLHYGQIVTYSCNRGFRLEGPSALTCLETGDWDVDAPSCNAIHC 426
Query: 647 GKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRC 706
+ G +E G++I YSC +++ G +TC EE WS S P C I C
Sbjct: 427 DSPQPIENGFVE--GADYSYGAIIIYSCFPGFQVAGHAMQTC-EESGWSSSIPTCMPIDC 483
Query: 707 SDP-----------------IVAEKSIVSV---TGNDRSHGHTLIRTSDNRDVG-----N 741
P E ++ V T + H + +T +N +
Sbjct: 484 GLPPHIDFGDCTKLKDDQGYFEQEDDMMEVPYVTPHPPYHLGAVAKTWENTKESPATHSS 543
Query: 742 TYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSN 801
+ G +V Y C GY+++G + C+++G W+G+ P+C ++C P ENG L
Sbjct: 544 NFLYGTMVSYTCNPGYELLGNPVLICQEDGTWNGSAPSCISIECDLPTAPENG--FLRFT 601
Query: 802 ATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVV 861
T G+ Y C L G R+C EN WS P C+ I+C P+ + GS +
Sbjct: 602 ETSMGSAVQYSCKPGHILAGSDLRLCLENRKWSGASPRCEAISCKKPN-PVMNGS---IK 657
Query: 862 TSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVIS 921
S + +Y+C+ GY L G + RTC W+ P+CIP+DC SP NG+ +
Sbjct: 658 GSNYTYLSTLYYECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDCSSPPVSANGQ--VR 715
Query: 922 NGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
F +E+ C + G R CL +G WSG P C
Sbjct: 716 GDEYTFQKEIEHTCNEGFLLEGARSRVCLANGSWSGATPDC 756
Score = 298 bits (732), Expect = 6e-80
Identities = 180/617 (29%), Positives = 274/617 (44%), Gaps = 49/617 (7%)
Query: 350 PPTCGSPDKLLNTTILGNDYDV-GSRIVYKCPEGHMLLGDKSRHCKKDGFW-SGAPPSCK 407
P +CG P K+ N + + S + Y+C G+ +G C+ + W S +P C
Sbjct: 71 PVSCGEPPKVENGFLEHTTGRIFESEVRYQCNPGYKSVGSPVFVCQANRHWHSESPLMCV 130
Query: 408 YVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEA-PRC 466
++CG PI++G + G++ + C E + LVG+ TC G W+ ++ P+C
Sbjct: 131 PLDCGKPPPIQNGFMK--GENFEVGSKVQFFCNEGYELVGDSSWTCQKSGKWNKKSNPKC 188
Query: 467 LFDWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKY 526
+ CP+PP + N V + +++C+ GH+L G + + C W+ P CK
Sbjct: 189 MPAKCPEPPLLENQLVLKELTTEVGVVTFSCKEGHVLQGPSVLKCLPSQQWNDSFPVCKI 248
Query: 527 VNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELT 586
V C P + + + +GS +++C ++L G +C DG WS +P C
Sbjct: 249 VLCTPPPLISFGVPIPSSALHFGSTVKYSCVGGFFLRGNSTTLCQPDGTWSSPLPECVPV 308
Query: 587 SCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDC 646
CP+PE G ++ ST + C+ G +L+G +C ++G W G PTC+ I+C
Sbjct: 309 ECPQPEEIPNGIIDVQGLAYLSTALYTCKPGFELVGNTTTLCGENGHWLGGKPTCKAIEC 368
Query: 647 GKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRC 706
K + G + H G ++ YSC +RL GP TC E W +P C I C
Sbjct: 369 LKPKEILNGKFSYTD--LHYGQIVTYSCNRGFRLEGPSALTCLETGDWDVDAPSCNAIHC 426
Query: 707 SDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLST 766
P E V G Y GA++ Y C G++V G ++ T
Sbjct: 427 DSPQPIENGFVE---------------------GADYSYGAIIIYSCFPGFQVAGHAMQT 465
Query: 767 CEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRM 826
CE++G WS + PTC +DCG P I+ G T + Y F Q D+ E+ V
Sbjct: 466 CEESG-WSSSIPTCMPIDCGLPPHIDFGDCTKLKDDQGY----FEQEDDMMEVPYVTPHP 520
Query: 827 CQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQT 886
G + KE P+ +S G Y C GY L G+
Sbjct: 521 PYHLGAVAKTWENTKE----SPATH----------SSNFLYGTMVSYTCNPGYELLGNPV 566
Query: 887 RTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFL 946
C G WNG+ P CI I+C P ENG + + T GS+V+Y C + G L
Sbjct: 567 LICQEDGTWNGSAPSCISIECDLPTAPENGFLRFT--ETSMGSAVQYSCKPGHILAGSDL 624
Query: 947 RKCLDDGRWSGEEPSCE 963
R CL++ +WSG P CE
Sbjct: 625 RLCLENRKWSGASPRCE 641
Score = 294 bits (722), Expect = 1e-78
Identities = 185/614 (30%), Positives = 267/614 (43%), Gaps = 36/614 (5%)
Query: 352 TCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNC 411
+C P+ ++N +I G++Y S + Y+C G++L G + R C+ D W P C V+C
Sbjct: 644 SCKKPNPVMNGSIKGSNYTYLSTLYYECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDC 703
Query: 412 GGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWC 471
+G V + T ++C E F L G R C G W G P C+ C
Sbjct: 704 SSPPVSANGQVR--GDEYTFQKEIEHTCNEGFLLEGARSRVCLANGSWSGATPDCVPVRC 761
Query: 472 PDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGT 531
PP ++N + ++ C G+IL G+ +TC G W P CK VNCG
Sbjct: 762 ATPPQLANGVTEGLDYGFMKEVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCKPVNCGP 821
Query: 532 PTIHKGSFVLING-TTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPE 590
P F NG + +G Q+ C P Y L+G C +G WS PSC C
Sbjct: 822 PEDLAHGFP--NGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCLPCRCST 879
Query: 591 PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLP 650
P V G + D+ C G KL+G + C+ DG+WS P CE+ CG LP
Sbjct: 880 P-VIEYGTVNGTDFDCGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHCEHTSCGSLP 938
Query: 651 TLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPI 710
+P + ++ +VI YSC + Y + G CTE+ WS P CE + C P
Sbjct: 939 MIPNAFIS--ETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPLSCGSP- 995
Query: 711 VAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGES-LSTCED 769
S+ + +H TY + VK RC +GY + ++ TC+
Sbjct: 996 ---PSVANAVATGEAH---------------TYE--SEVKLRCLEGYTMDTDTDTITCQK 1035
Query: 770 NGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQE 829
+G+W +C C P I + + + + C E + EGV +CQ
Sbjct: 1036 DGRWFPERISCSPKKCPLPENITH--ILVHGDDFSVNRQVSVSCAEGYTFEGVNISVCQL 1093
Query: 830 NGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTC 889
+GTW EPP E P + ++ VV S + YQCE GY L+G++ R C
Sbjct: 1094 DGTW--EPPFSDESCSPVSCGKPESPEHGFVVGSKYTFESTIIYQCEPGYELEGNRERVC 1151
Query: 890 ISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKC 949
QW+G V +C C +P NGK I N +T G +V Y C Y GP C
Sbjct: 1152 QENRQWSGGVAICKETRCETPLEFLNGKADIENRTT--GPNVVYSCNRGYSLEGPSEAHC 1209
Query: 950 LDDGRWSGEEPSCE 963
++G WS P C+
Sbjct: 1210 TENGTWSHPVPLCK 1223
Score = 291 bits (713), Expect = 1e-77
Identities = 179/620 (28%), Positives = 269/620 (43%), Gaps = 50/620 (8%)
Query: 353 CGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCG 412
C P N + + +GS + Y C GH+L G R C ++ WSGA P C+ ++C
Sbjct: 587 CDLPTAPENGFLRFTETSMGSAVQYSCKPGHILAGSDLRLCLENRKWSGASPRCEAISCK 646
Query: 413 GLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCP 472
P+ +G + + T+ + Y C + L G RTC D+ WD + P C+ C
Sbjct: 647 KPNPVMNGSIK--GSNYTYLSTLYYECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDCS 704
Query: 473 DPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTP 532
PP +N V + + +TC G +L G+ S C G+WSG P C V C TP
Sbjct: 705 SPPVSANGQVRGDEYTFQKEIEHTCNEGFLLEGARSRVCLANGSWSGATPDCVPVRCATP 764
Query: 533 TIHKGSFVLINGTT---TYGSIAQ--FTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTS 587
L NG T YG + + F C Y L+GA +L C DG W +IP C+ +
Sbjct: 765 P------QLANGVTEGLDYGFMKEVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCKPVN 818
Query: 588 CPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCG 647
C PE + G+ F + I + C G+KL G + C +G WSG SP+C C
Sbjct: 819 CGPPEDLAHGFPNGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCLPCRC- 877
Query: 648 KLPTLPYGTMELLNGTT-HLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRC 706
P + YGT +NGT G + C ++L+G TC + QWS P CE C
Sbjct: 878 STPVIEYGT---VNGTDFDCGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHCEHTSC 934
Query: 707 SDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLST 766
+ + +S T + + + ++ Y C GY + G S
Sbjct: 935 GSLPMIPNAFISETSSWKEN---------------------VITYSCRSGYVIQGSSDLI 973
Query: 767 CEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRM 826
C + G WS P C+ + CG+P + N T A Y + +C E + ++ +
Sbjct: 974 CTEKGVWSQPYPVCEPLSCGSPPSVANAVAT--GEAHTYESEVKLRCLEGYTMDTDTDTI 1031
Query: 827 -CQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQ 885
CQ++G W E C CP P + + +LV S+ + C GY +G
Sbjct: 1032 TCQKDGRWFPERISCSPKKCPLP----ENITHILVHGDDFSVNRQVSVSCAEGYTFEGVN 1087
Query: 886 TRTCISKGQWNG--TVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVG 943
C G W + C P+ C P + E+G +V S + F S++ Y C Y+ G
Sbjct: 1088 ISVCQLDGTWEPPFSDESCSPVSCGKPESPEHGFVVGSKYT--FESTIIYQCEPGYELEG 1145
Query: 944 PFLRKCLDDGRWSGEEPSCE 963
R C ++ +WSG C+
Sbjct: 1146 NRERVCQENRQWSGGVAICK 1165
Score = 289 bits (710), Expect = 3e-77
Identities = 176/586 (30%), Positives = 254/586 (43%), Gaps = 38/586 (6%)
Query: 372 GSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRTTH 431
G+ + Y C G+ LLG+ C++DG W+G+ PSC + C T E+G + + T+
Sbjct: 548 GTMVSYTCNPGYELLGNPVLICQEDGTWNGSAPSCISIECDLPTAPENGFLRFTE--TSM 605
Query: 432 GARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGS 491
G+ YSC+ L G+ R C + W G +PRC C P V N S+ + + S
Sbjct: 606 GSAVQYSCKPGHILAGSDLRLCLENRKWSGASPRCEAISCKKPNPVMNGSIKGSNYTYLS 665
Query: 492 LASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTIHKGSFVLINGTTTYGSI 551
Y C+ G++L+G+ TC W P C V+C +P + V T+
Sbjct: 666 TLYYECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDCSSPPVSANGQVR-GDEYTFQKE 724
Query: 552 AQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFDYYVHSTIN 611
+ TC + L GA VC +G WS P C C P + G E DY +
Sbjct: 725 IEHTCNEGFLLEGARSRVCLANGSWSGATPDCVPVRCATPPQLANGVTEGLDYGFMKEVT 784
Query: 612 FHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHL-GSVI 670
FHC G+ L G P L CQ DG W + P C+ ++CG L +G NG + + G I
Sbjct: 785 FHCHEGYILHGAPKLTCQSDGNWDAEIPLCKPVNCGPPEDLAHG---FPNGFSFIHGGHI 841
Query: 671 QYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTL 730
QY C Y+L G R C WS SSP C RCS P++ +V G D
Sbjct: 842 QYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCLPCRCSTPVI---EYGTVNGTD------- 891
Query: 731 IRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGR 790
D G RI +C KG+K++G S TCE +GQWS P C++ CG+
Sbjct: 892 ------FDCGKAARI------QCFKGFKLLGLSEITCEADGQWSSGFPHCEHTSCGSLPM 939
Query: 791 IENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSA 850
I N ++ +++ Y C + ++G +C E G WS P+C+ ++C P +
Sbjct: 940 IPNAFIS--ETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPLSCGSPPS 997
Query: 851 QIKAGSGLLVVTSTLSIGGEAHYQCERGYNL-KGHQTRTCISKGQWNGTVPVCIPIDCRS 909
A + + E +C GY + T TC G+W C P C
Sbjct: 998 VANA----VATGEAHTYESEVKLRCLEGYTMDTDTDTITCQKDGRWFPERISCSPKKCPL 1053
Query: 910 PGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRW 955
P NI + I++ V C Y G + C DG W
Sbjct: 1054 PENITH--ILVHGDDFSVNRQVSVSCAEGYTFEGVNISVCQLDGTW 1097
Score = 284 bits (696), Expect = 1e-75
Identities = 182/621 (29%), Positives = 267/621 (42%), Gaps = 43/621 (6%)
Query: 349 LPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKY 408
+P C SP N + G++Y I + C EG +L G +SR C +G WSGA P C
Sbjct: 699 IPVDCSSPPVSANGQVRGDEYTFQKEIEHTCNEGFLLEGARSRVCLANGSWSGATPDCVP 758
Query: 409 VNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLF 468
V C + +G +D + C E + L G P+ TC +G WD E P C
Sbjct: 759 VRCATPPQLANGVTEGLDYGFMK--EVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCKP 816
Query: 469 DWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVN 528
C P +++ G Y C G+ L G++S C G+WSG PSC
Sbjct: 817 VNCGPPEDLAHGFPNGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCLPCR 876
Query: 529 CGTPTIHKGSFVLINGTT-TYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTS 587
C TP I G+ +NGT G A+ C + L G E+ C DG+WS P CE TS
Sbjct: 877 CSTPVIEYGT---VNGTDFDCGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHCEHTS 933
Query: 588 CPE-PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDC 646
C P +P+ ++ + + I + C +G+ + G +L+C + G WS P CE + C
Sbjct: 934 CGSLPMIPN-AFISETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPLSC 992
Query: 647 GKLPTLPYGTMELLNGTTH-LGSVIQYSCTTNYRL-VGPVRRTCTEEFQWSDSSPRCEEI 704
G P++ + G H S ++ C Y + TC ++ +W C
Sbjct: 993 GSPPSV---ANAVATGEAHTYESEVKLRCLEGYTMDTDTDTITCQKDGRWFPERISCSPK 1049
Query: 705 RCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESL 764
+C P ++T H L+ G+ + + V C +GY G ++
Sbjct: 1050 KCPLP-------ENIT-------HILVH-------GDDFSVNRQVSVSCAEGYTFEGVNI 1088
Query: 765 STCEDNGQWSG--TTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGV 822
S C+ +G W + +C V CG P E+G V + S TF +T YQC+ +ELEG
Sbjct: 1089 SVCQLDGTWEPPFSDESCSPVSCGKPESPEHGFV-VGSKYTF-ESTIIYQCEPGYELEGN 1146
Query: 823 IRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLK 882
R+CQEN WS ICKE C P + + + + G Y C RGY+L+
Sbjct: 1147 RERVCQENRQWSGGVAICKETRCETPLEFLNGKADI----ENRTTGPNVVYSCNRGYSLE 1202
Query: 883 GHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRV 942
G C G W+ VP+C P C P I + +S +V C +
Sbjct: 1203 GPSEAHCTENGTWSHPVPLCKPNPCPVPFVIPENAL-LSEKEFYVDQNVSIKCREGFLLQ 1261
Query: 943 GPFLRKCLDDGRWSGEEPSCE 963
G + C D W+ CE
Sbjct: 1262 GHGIITCNPDETWTQTSAKCE 1282
Score = 274 bits (673), Expect = 8e-73
Identities = 176/621 (28%), Positives = 254/621 (40%), Gaps = 46/621 (7%)
Query: 349 LPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKY 408
+P C +P +L N G DY + + C EG++L G C+ DG W P CK
Sbjct: 757 VPVRCATPPQLANGVTEGLDYGFMKEVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCKP 816
Query: 409 VNCGGLTPIEDGDVALIDNRT-THGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL 467
VNCG P ED + + HG Y C + L GN R C G W G +P CL
Sbjct: 817 VNCG---PPEDLAHGFPNGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCL 873
Query: 468 FDWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYV 527
C P + +V G A C G L G + +TC G WS P C++
Sbjct: 874 PCRC-STPVIEYGTVNGTDFDCGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHCEHT 932
Query: 528 NCGTPTIHKGSFVLINGTTTYG-SIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELT 586
+CG+ + +F I+ T+++ ++ ++C Y + G+ +L+C G WS P CE
Sbjct: 933 SCGSLPMIPNAF--ISETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPL 990
Query: 587 SCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLV-CQQDGEWSGDSPTCEYID 645
SC P + + S + C G+ + + + + CQ+DG W + +C
Sbjct: 991 SCGSPPSVANAVATGEAHTYESEVKLRCLEGYTMDTDTDTITCQKDGRWFPERISCSPKK 1050
Query: 646 CGKLPTLPYGTMELLNGTTH-LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSD--SSPRCE 702
C P T L++G + + SC Y G C + W S C
Sbjct: 1051 C---PLPENITHILVHGDDFSVNRQVSVSCAEGYTFEGVNISVCQLDGTWEPPFSDESCS 1107
Query: 703 EIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGE 762
+ C P E HG VG+ Y + + Y+CE GY++ G
Sbjct: 1108 PVSCGKPESPE------------HGFV---------VGSKYTFESTIIYQCEPGYELEGN 1146
Query: 763 SLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGV 822
C++N QWSG C+ C P NGK + + T G Y C+ + LEG
Sbjct: 1147 RERVCQENRQWSGGVAICKETRCETPLEFLNGKADIENRTT--GPNVVYSCNRGYSLEGP 1204
Query: 823 IRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLK 882
C ENGTWS P+CK CP P L+ + +C G+ L+
Sbjct: 1205 SEAHCTENGTWSHPVPLCKPNPCPVP---FVIPENALLSEKEFYVDQNVSIKCREGFLLQ 1261
Query: 883 GHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRV 942
GH TC W T C I C P ++EN + +G + Y C S Y
Sbjct: 1262 GHGIITCNPDETWTQTSAKCEKISCGPPAHVENA--IARGVHYQYGDMITYSCYSGYMLE 1319
Query: 943 GPFLRK-CLDDGRWSGEEPSC 962
G FLR CL++G W+ P C
Sbjct: 1320 G-FLRSVCLENGTWT-SPPIC 1338
Score = 264 bits (647), Expect = 1e-69
Identities = 165/537 (30%), Positives = 231/537 (43%), Gaps = 42/537 (7%)
Query: 431 HGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAG 490
+G Y+C + L+GNP C ++G W+G AP C+ C P A N + G
Sbjct: 547 YGTMVSYTCNPGYELLGNPVLICQEDGTWNGSAPSCISIECDLPTAPENGFLRFTETSMG 606
Query: 491 SLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPT-IHKGSFVLINGTT-TY 548
S Y+C+ GHIL+GS C WSG P C+ ++C P + GS I G+ TY
Sbjct: 607 SAVQYSCKPGHILAGSDLRLCLENRKWSGASPRCEAISCKKPNPVMNGS---IKGSNYTY 663
Query: 549 GSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFDYYVHS 608
S + C+P Y LNG E C D W D P C C P V + G + +Y
Sbjct: 664 LSTLYYECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDCSSPPVSANGQVRGDEYTFQK 723
Query: 609 TINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGS 668
I C G L G + VC +G WSG +P C + C P L G E L+
Sbjct: 724 EIEHTCNEGFLLEGARSRVCLANGSWSGATPDCVPVRCATPPQLANGVTEGLD--YGFMK 781
Query: 669 VIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGH 728
+ + C Y L G + TC + W P C+ + C P D +HG
Sbjct: 782 EVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCKPVNCGPP------------EDLAHGF 829
Query: 729 TLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNP 788
G ++ G ++Y+C GYK+ G S C NG WSG++P+C C P
Sbjct: 830 ---------PNGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCLPCRCSTP 880
Query: 789 GRIENGKVTLPSNATFY--GATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCP 846
IE G V N T + G A QC + ++L G+ C+ +G WS P C+ +C
Sbjct: 881 -VIEYGTV----NGTDFDCGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHCEHTSC- 934
Query: 847 DPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPID 906
+ + + TS+ Y C GY ++G C KG W+ PVC P+
Sbjct: 935 --GSLPMIPNAFISETSSWK-ENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPLS 991
Query: 907 CRSPGNIENGKIVISNGSTLFGSSVEYYCLSQY-QRVGPFLRKCLDDGRWSGEEPSC 962
C SP ++ N V + + + S V+ CL Y C DGRW E SC
Sbjct: 992 CGSPPSVANA--VATGEAHTYESEVKLRCLEGYTMDTDTDTITCQKDGRWFPERISC 1046
Score = 247 bits (605), Expect = 1e-64
Identities = 144/505 (28%), Positives = 221/505 (43%), Gaps = 31/505 (6%)
Query: 347 QYLPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSC 406
Q +P CG P ++N G++Y G+ + Y C +G + G+K C+ G WS P+C
Sbjct: 10 QCIPVRCGEPPSIMNGYASGSNYSFGAMVAYSCNKGFYIEGEKKSTCEATGQWSSPIPTC 69
Query: 407 KYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAP-R 465
V+CG +E+G + R + Y C + VG+P C W E+P
Sbjct: 70 HPVSCGEPPKVENGFLEHTTGRIFE-SEVRYQCNPGYKSVGSPVFVCQANRHWHSESPLM 128
Query: 466 CLFDWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVP-PSC 524
C+ C PP + N + + GS + C G+ L G +S TC G W+ P C
Sbjct: 129 CVPLDCGKPPPIQNGFMKGENFEVGSKVQFFCNEGYELVGDSSWTCQKSGKWNKKSNPKC 188
Query: 525 KYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCE 584
C P + + VL TT G + F+C+ + L G L C +W+ P C+
Sbjct: 189 MPAKCPEPPLLENQLVLKELTTEVG-VVTFSCKEGHVLQGPSVLKCLPSQQWNDSFPVCK 247
Query: 585 LTSC-PEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEY 643
+ C P P + G + + + ST+ + C G L G +CQ DG WS P C
Sbjct: 248 IVLCTPPPLISFGVPIPSSALHFGSTVKYSCVGGFFLRGNSTTLCQPDGTWSSPLPECVP 307
Query: 644 IDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEE 703
++C + +P G ++ + G +L + + Y+C + LVG C E W P C+
Sbjct: 308 VECPQPEEIPNGIID-VQGLAYLSTAL-YTCKPGFELVGNTTTLCGENGHWLGGKPTCKA 365
Query: 704 IRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGES 763
I C P K I+ + +T G +V Y C +G+++ G S
Sbjct: 366 IECLKP----KEIL-----NGKFSYT------------DLHYGQIVTYSCNRGFRLEGPS 404
Query: 764 LSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVI 823
TC + G W P+C + C +P IENG V + YGA Y C +++ G
Sbjct: 405 ALTCLETGDWDVDAPSCNAIHCDSPQPIENGFVEGADYS--YGAIIIYSCFPGFQVAGHA 462
Query: 824 RRMCQENGTWSLEPPICKEITCPDP 848
+ C+E+G WS P C I C P
Sbjct: 463 MQTCEESG-WSSSIPTCMPIDCGLP 486
Score = 241 bits (589), Expect = 1e-62
Identities = 147/502 (29%), Positives = 221/502 (44%), Gaps = 40/502 (7%)
Query: 349 LPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKY 408
LP C +P + T+ G D+D G +C +G LLG C+ DG WS P C++
Sbjct: 873 LPCRCSTP-VIEYGTVNGTDFDCGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHCEH 931
Query: 409 VNCGGLTPIEDGDVALIDNRTTHGARAL-YSCRENFTLVGNPERTCGDEGIWDGEAPRCL 467
+CG L I + A I ++ + YSCR + + G+ + C ++G+W P C
Sbjct: 932 TSCGSLPMIPN---AFISETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCE 988
Query: 468 FDWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGST-SVTCTLGGAWSGVPPSCKY 526
C PP+V+NA T H S C G+ + T ++TC G W SC
Sbjct: 989 PLSCGSPPSVANAVATGEAHTYESEVKLRCLEGYTMDTDTDTITCQKDGRWFPERISCSP 1048
Query: 527 VNCGTPTIHKGSFVLINGTT-TYGSIAQFTCEPDYWLNGAEELVCNRDGKWS--YDIPSC 583
C P + +L++G + +C Y G VC DG W + SC
Sbjct: 1049 KKCPLP--ENITHILVHGDDFSVNRQVSVSCAEGYTFEGVNISVCQLDGTWEPPFSDESC 1106
Query: 584 ELTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEY 643
SC +PE P G++ Y STI + CE G++L G VCQ++ +WSG C+
Sbjct: 1107 SPVSCGKPESPEHGFVVGSKYTFESTIIYQCEPGYELEGNRERVCQENRQWSGGVAICKE 1166
Query: 644 IDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEE 703
C G ++ N TT G + YSC Y L GP CTE WS P C+
Sbjct: 1167 TRCETPLEFLNGKADIENRTT--GPNVVYSCNRGYSLEGPSEAHCTENGTWSHPVPLCKP 1224
Query: 704 IRCSDP-IVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGE 762
C P ++ E +++S + + V +C +G+ + G
Sbjct: 1225 NPCPVPFVIPENALLS---------------------EKEFYVDQNVSIKCREGFLLQGH 1263
Query: 763 SLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATF-YGATAFYQCDENWELEG 821
+ TC + W+ T+ C+ + CG P +EN + + YG Y C + LEG
Sbjct: 1264 GIITCNPDETWTQTSAKCEKISCGPPAHVEN---AIARGVHYQYGDMITYSCYSGYMLEG 1320
Query: 822 VIRRMCQENGTWSLEPPICKEI 843
+R +C ENGTW+ PPIC+ +
Sbjct: 1321 FLRSVCLENGTWT-SPPICRAV 1341
Score = 153 bits (370), Expect = 4e-36
Identities = 103/369 (27%), Positives = 145/369 (39%), Gaps = 13/369 (3%)
Query: 345 ICQYLPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSR-HCKKDGFWSGAP 403
+C+ P +CGSP + N G + S + +C EG+ + D C+KDG W
Sbjct: 986 VCE--PLSCGSPPSVANAVATGEAHTYESEVKLRCLEGYTMDTDTDTITCQKDGRWFPER 1043
Query: 404 PSCKYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDG-- 461
SC C P + + + + + SC E +T G C +G W+
Sbjct: 1044 ISCSPKKCP--LPENITHILVHGDDFSVNRQVSVSCAEGYTFEGVNISVCQLDGTWEPPF 1101
Query: 462 EAPRCLFDWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVP 521
C C P + + V + + S Y CE G+ L G+ C WSG
Sbjct: 1102 SDESCSPVSCGKPESPEHGFVVGSKYTFESTIIYQCEPGYELEGNRERVCQENRQWSGGV 1161
Query: 522 PSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIP 581
CK C TP I TT G ++C Y L G E C +G WS+ +P
Sbjct: 1162 AICKETRCETPLEFLNGKADIENRTT-GPNVVYSCNRGYSLEGPSEAHCTENGTWSHPVP 1220
Query: 582 SCELTSCPEPEV-PSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPT 640
C+ CP P V P + ++YV ++ C G L G + C D W+ S
Sbjct: 1221 LCKPNPCPVPFVIPENALLSEKEFYVDQNVSIKCREGFLLQGHGIITCNPDETWTQTSAK 1280
Query: 641 CEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPR 700
CE I CG P G +I YSC + Y L G +R C E W+ S P
Sbjct: 1281 CEKISCG--PPAHVENAIARGVHYQYGDMITYSCYSGYMLEGFLRSVCLENGTWT-SPPI 1337
Query: 701 CEEIRCSDP 709
C + C P
Sbjct: 1338 CRAV-CRFP 1345
Score = 140 bits (339), Expect = 2e-32
Identities = 76/227 (33%), Positives = 111/227 (48%), Gaps = 9/227 (3%)
Query: 740 GNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLP 799
G+ Y GA+V Y C KG+ + GE STCE GQWS PTC V CG P ++ENG +
Sbjct: 29 GSNYSFGAMVAYSCNKGFYIEGEKKSTCEATGQWSSPIPTCHPVSCGEPPKVENGFLEHT 88
Query: 800 SNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPI-CKEITCPDPSAQIKAGSGL 858
+ F YQC+ ++ G +CQ N W E P+ C + C P I+ G
Sbjct: 89 TGRIFESEVR-YQCNPGYKSVGSPVFVCQANRHWHSESPLMCVPLDCGKP-PPIQNG--- 143
Query: 859 LVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWN-GTVPVCIPIDCRSPGNIENGK 917
+ +G + + C GY L G + TC G+WN + P C+P C P +EN +
Sbjct: 144 FMKGENFEVGSKVQFFCNEGYELVGDSSWTCQKSGKWNKKSNPKCMPAKCPEPPLLEN-Q 202
Query: 918 IVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCEL 964
+V+ +T G V + C + GP + KCL +W+ P C++
Sbjct: 203 LVLKELTTEVG-VVTFSCKEGHVLQGPSVLKCLPSQQWNDSFPVCKI 248
Score = 43.2 bits (97), Expect = 0.005
Identities = 27/72 (37%), Positives = 35/72 (48%), Gaps = 6/72 (8%)
Query: 894 QWNGTVPV---CIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCL 950
QWN + P+ CIP+ C P +I NG SN S FG+ V Y C + G C
Sbjct: 1 QWNPS-PMSIQCIPVRCGEPPSIMNGYASGSNYS--FGAMVAYSCNKGFYIEGEKKSTCE 57
Query: 951 DDGRWSGEEPSC 962
G+WS P+C
Sbjct: 58 ATGQWSSPIPTC 69
Score = 42.3 bits (95), Expect = 0.009
Identities = 22/61 (36%), Positives = 26/61 (42%), Gaps = 3/61 (4%)
Query: 1 RCGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGT 60
RC P N + I EN G VY C+ GY L G + CT G W+ P C
Sbjct: 1168 RCETPLEFLNGKADI---ENRTTGPNVVYSCNRGYSLEGPSEAHCTENGTWSHPVPLCKP 1224
Query: 61 N 61
N
Sbjct: 1225 N 1225
Score = 37.5 bits (83), Expect = 0.26
Identities = 23/77 (29%), Positives = 29/77 (37%), Gaps = 7/77 (9%)
Query: 8 PPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTNVAFRKP 67
P + PN + + G Y+C GY+L G R C G W+ P C P
Sbjct: 822 PEDLAHGFPNGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSC-------LP 874
Query: 68 ANQSTTVRGGAAANGND 84
ST V NG D
Sbjct: 875 CRCSTPVIEYGTVNGTD 891
Score = 37.1 bits (82), Expect = 0.34
Identities = 16/58 (27%), Positives = 26/58 (44%), Gaps = 3/58 (5%)
Query: 1 RCGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
RCG P P+ + N G + Y C++G+ + G ++ C G W+ P C
Sbjct: 15 RCGEP---PSIMNGYASGSNYSFGAMVAYSCNKGFYIEGEKKSTCEATGQWSSPIPTC 69
Score = 35.9 bits (79), Expect = 0.79
Identities = 17/48 (35%), Positives = 22/48 (45%)
Query: 29 YECDEGYELFGARQRECTLRGDWTLEPPFCGTNVAFRKPANQSTTVRG 76
YECD GY L G +R C +W + P C P + + VRG
Sbjct: 669 YECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDCSSPPVSANGQVRG 716
Score = 35.5 bits (78), Expect = 1.0
Identities = 13/35 (37%), Positives = 17/35 (48%)
Query: 24 GTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
G I Y C+ G+ L G C GDW ++ P C
Sbjct: 387 GQIVTYSCNRGFRLEGPSALTCLETGDWDVDAPSC 421
Score = 35.1 bits (77), Expect = 1.4
Identities = 20/57 (35%), Positives = 26/57 (45%), Gaps = 3/57 (5%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C P V N +V +E I + C+EG+ L GAR R C G W+ P C
Sbjct: 703 CSSPPVSANGQVR--GDEYTFQKEIE-HTCNEGFLLEGARSRVCLANGSWSGATPDC 756
Score = 34.7 bits (76), Expect = 1.8
Identities = 15/42 (35%), Positives = 19/42 (45%)
Query: 17 NEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
+ N + GT+ Y C+ GYEL G C G W P C
Sbjct: 541 HSSNFLYGTMVSYTCNPGYELLGNPVLICQEDGTWNGSAPSC 582
Score = 34.7 bits (76), Expect = 1.8
Identities = 21/57 (36%), Positives = 24/57 (42%), Gaps = 4/57 (7%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
CG PA NA I + G + Y C GY L G + C G WT PP C
Sbjct: 1286 CGPPAHVENA---IARGVHYQYGDMITYSCYSGYMLEGFLRSVCLENGTWT-SPPIC 1338
Score = 34.3 bits (75), Expect = 2.4
Identities = 18/57 (31%), Positives = 26/57 (45%), Gaps = 3/57 (5%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
CG + PNA +S E + + Y C GY + G+ CT +G W+ P C
Sbjct: 934 CGSLPMIPNAFIS---ETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVC 987
Score = 34.3 bits (75), Expect = 2.4
Identities = 18/51 (35%), Positives = 25/51 (49%), Gaps = 3/51 (5%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWT 52
CG P P + V + TI +Y+C+ GYEL G R+R C W+
Sbjct: 1111 CGKPESPEHGFVV--GSKYTFESTI-IYQCEPGYELEGNRERVCQENRQWS 1158
Score = 33.5 bits (73), Expect = 4.2
Identities = 13/30 (43%), Positives = 16/30 (53%)
Query: 29 YECDEGYELFGARQRECTLRGDWTLEPPFC 58
+ C EGY L GA + C G+W E P C
Sbjct: 785 FHCHEGYILHGAPKLTCQSDGNWDAEIPLC 814
Score = 33.1 bits (72), Expect = 5.6
Identities = 15/44 (34%), Positives = 19/44 (43%)
Query: 8 PPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDW 51
PP + EN G+ + C+EGYEL G C G W
Sbjct: 137 PPPIQNGFMKGENFEVGSKVQFFCNEGYELVGDSSWTCQKSGKW 180
>AK075235-1|BAC11489.1| 1497|Homo sapiens protein ( Homo sapiens
cDNA FLJ90754 fis, clone PLACE4000354, weakly similar to
COMPLEMENT RECEPTOR TYPE 1 PRECURSOR. ).
Length = 1497
Score = 301 bits (740), Expect = 6e-81
Identities = 185/642 (28%), Positives = 282/642 (43%), Gaps = 41/642 (6%)
Query: 348 YLPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSG-APPSC 406
++P CG P + N + G +++VGS++ + C EG+ L+GD S C+K G W+ + P C
Sbjct: 185 WVPLDCGKPPPIQNGFMKGENFEVGSKVQFFCNEGYELVGDSSWTCQKSGKWNKKSNPKC 244
Query: 407 KYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRC 466
C P+ + + L + T G +SC+E L G C W+ P C
Sbjct: 245 MPAKCPE-PPLLENQLVLKELTTEVGV-VTFSCKEGHVLQGPSVLKCLPSQQWNDSFPVC 302
Query: 467 LFDWCPDPPAVS-NASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCK 525
C PP +S + + GS Y+C G L G+++ C G WS P C
Sbjct: 303 KIVLCTPPPLISFGVPIPSSALHFGSTVKYSCVGGFFLRGNSTTLCQPDGTWSSPLPECV 362
Query: 526 YVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCEL 585
V C P + + G Y S A +TC+P + L G +C +G W P+C+
Sbjct: 363 PVECPQPEEIPNGIIDVRGLA-YLSTALYTCKPGFELVGNTTTLCGENGHWLGGKPTCKA 421
Query: 586 TSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYID 645
C +P+ G D + T+ + C G +L G L C + G+W D+P+C I
Sbjct: 422 IECLKPKEILNGKFSYTDLHYGQTVTYSCNRGFRLEGPSALTCLETGDWDVDAPSCNAIH 481
Query: 646 CGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIR 705
C + G +E G++I YSC +++ G +TC EE WS S P C I
Sbjct: 482 CDSPQPIENGFVE--GADYSYGAIIIYSCFPGFQVAGHAMQTC-EESGWSSSIPTCMPID 538
Query: 706 CSDP-----------------IVAEKSIVS---VTGNDRSHGHTLIRTSDNRDV-----G 740
C P E ++ VT + H + +T +N
Sbjct: 539 CGLPPHIDFGDCTKLKDDQGYFEQEDDMMEVPYVTPHPPYHLGAVAKTWENTKESPATHS 598
Query: 741 NTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPS 800
+ + G +V Y C GY+++G + C+++G +G+ P+C ++C P ENG L
Sbjct: 599 SNFLYGTMVSYTCNPGYELLGNPVLICQEDGTRNGSAPSCISIECDLPTAPENG--FLRF 656
Query: 801 NATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLV 860
T G+ Y C L G R+C EN WS P C+ I+C P+ + GS +
Sbjct: 657 TETSMGSAVQYSCKPGHILVGSGLRLCLENRKWSGASPRCEAISCKKPN-PVMNGS---I 712
Query: 861 VTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVI 920
S + +Y+C+ GY L G + RTC W+ P+CIP+D SP NG+ +
Sbjct: 713 KGSNYTYLSTLYYECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDRSSPPVSANGQ--V 770
Query: 921 SNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
F +EY C + G R CL +G WSG P C
Sbjct: 771 RGDEYTFQKEIEYTCNEGFLLEGARSRVCLANGSWSGATPDC 812
Score = 288 bits (707), Expect = 6e-77
Identities = 179/620 (28%), Positives = 268/620 (43%), Gaps = 50/620 (8%)
Query: 353 CGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCG 412
C P N + + +GS + Y C GH+L+G R C ++ WSGA P C+ ++C
Sbjct: 643 CDLPTAPENGFLRFTETSMGSAVQYSCKPGHILVGSGLRLCLENRKWSGASPRCEAISCK 702
Query: 413 GLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCP 472
P+ +G + + T+ + Y C + L G RTC D+ WD + P C+
Sbjct: 703 KPNPVMNGSIK--GSNYTYLSTLYYECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDRS 760
Query: 473 DPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTP 532
PP +N V + + YTC G +L G+ S C G+WSG P C V C TP
Sbjct: 761 SPPVSANGQVRGDEYTFQKEIEYTCNEGFLLEGARSRVCLANGSWSGATPDCVPVRCATP 820
Query: 533 TIHKGSFVLINGTT---TYGSIAQ--FTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTS 587
L NG T YG + + F C Y L+GA +L C DG W +IP C+ +
Sbjct: 821 P------QLANGVTEGLDYGFMKEVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCKPVN 874
Query: 588 CPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCG 647
C PE + G+ F + I + C G+KL G + C +G WSG SP+C C
Sbjct: 875 CGPPEDLAHGFPNGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCLPFRC- 933
Query: 648 KLPTLPYGTMELLNGTT-HLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRC 706
P + YGT +NGT G + C ++L+G TC + QWS P CE C
Sbjct: 934 STPVIEYGT---VNGTDFDCGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHCEHTSC 990
Query: 707 SDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLST 766
+ + +S T + + + ++ Y C GY + G S
Sbjct: 991 GSLPMIPNAFISETSSWKEN---------------------VITYSCRSGYVIQGSSDLI 1029
Query: 767 CEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELE-GVIRR 825
C + G WS P C+ + CG+P + N T A Y + +C E + ++
Sbjct: 1030 CTEKGVWSQPYPVCEPLSCGSPPSVANAVAT--GEAHTYESEVKLRCLEGYTMDTDTDTF 1087
Query: 826 MCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQ 885
CQ++G W E C CP P + + +LV S+ + C GY +G
Sbjct: 1088 TCQKDGRWFPERISCSPKKCPLP----ENITHILVHGDDFSVNRQVSVSCAEGYTFEGVN 1143
Query: 886 TRTCISKGQWNG--TVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVG 943
C G W + C P+ C P + E+G +V S + F S++ Y C Y+ G
Sbjct: 1144 ISVCQLDGTWEPPFSDESCSPVSCGKPESPEHGFVVGSKYT--FESTIIYQCEPGYELEG 1201
Query: 944 PFLRKCLDDGRWSGEEPSCE 963
R C ++ +WSG C+
Sbjct: 1202 NRERVCQENRQWSGGVAICK 1221
Score = 288 bits (706), Expect = 8e-77
Identities = 184/614 (29%), Positives = 265/614 (43%), Gaps = 36/614 (5%)
Query: 352 TCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNC 411
+C P+ ++N +I G++Y S + Y+C G++L G + R C+ D W P C V+
Sbjct: 700 SCKKPNPVMNGSIKGSNYTYLSTLYYECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDR 759
Query: 412 GGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWC 471
+G V + T Y+C E F L G R C G W G P C+ C
Sbjct: 760 SSPPVSANGQVR--GDEYTFQKEIEYTCNEGFLLEGARSRVCLANGSWSGATPDCVPVRC 817
Query: 472 PDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGT 531
PP ++N + ++ C G+IL G+ +TC G W P CK VNCG
Sbjct: 818 ATPPQLANGVTEGLDYGFMKEVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCKPVNCGP 877
Query: 532 PTIHKGSFVLING-TTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPE 590
P F NG + +G Q+ C P Y L+G C +G WS PSC C
Sbjct: 878 PEDLAHGFP--NGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCLPFRCST 935
Query: 591 PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLP 650
P V G + D+ C G KL+G + C+ DG+WS P CE+ CG LP
Sbjct: 936 P-VIEYGTVNGTDFDCGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHCEHTSCGSLP 994
Query: 651 TLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPI 710
+P + ++ +VI YSC + Y + G CTE+ WS P CE + C P
Sbjct: 995 MIPNAFIS--ETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPLSCGSP- 1051
Query: 711 VAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGES-LSTCED 769
S+ + +H TY + VK RC +GY + ++ TC+
Sbjct: 1052 ---PSVANAVATGEAH---------------TYE--SEVKLRCLEGYTMDTDTDTFTCQK 1091
Query: 770 NGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQE 829
+G+W +C C P I + + + + C E + EGV +CQ
Sbjct: 1092 DGRWFPERISCSPKKCPLPENITH--ILVHGDDFSVNRQVSVSCAEGYTFEGVNISVCQL 1149
Query: 830 NGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTC 889
+GTW EPP E P + ++ VV S + YQCE GY L+G++ R C
Sbjct: 1150 DGTW--EPPFSDESCSPVSCGKPESPEHGFVVGSKYTFESTIIYQCEPGYELEGNRERVC 1207
Query: 890 ISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKC 949
QW+G V +C C + NGK I N +T G +V Y C Y GP C
Sbjct: 1208 QENRQWSGGVAICKETRCETQLEFLNGKADIENRTT--GPNVVYSCNRGYSLEGPSEAHC 1265
Query: 950 LDDGRWSGEEPSCE 963
++G WS P C+
Sbjct: 1266 TENGTWSHPVPLCK 1279
Score = 287 bits (705), Expect = 1e-76
Identities = 179/617 (29%), Positives = 271/617 (43%), Gaps = 49/617 (7%)
Query: 350 PPTCGSPDKLLNTTILGNDYDV-GSRIVYKCPEGHMLLGDKSRHCKKDGFW-SGAPPSCK 407
P +CG P K+ N + + S + Y+C G+ +G C + W S +P
Sbjct: 127 PVSCGEPPKVENGFLEHTTGRIFESEVRYQCNPGYKPVGSPVFVCHANRHWHSESPLMWV 186
Query: 408 YVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEA-PRC 466
++CG PI++G + G++ + C E + LVG+ TC G W+ ++ P+C
Sbjct: 187 PLDCGKPPPIQNGFMK--GENFEVGSKVQFFCNEGYELVGDSSWTCQKSGKWNKKSNPKC 244
Query: 467 LFDWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKY 526
+ CP+PP + N V + +++C+ GH+L G + + C W+ P CK
Sbjct: 245 MPAKCPEPPLLENQLVLKELTTEVGVVTFSCKEGHVLQGPSVLKCLPSQQWNDSFPVCKI 304
Query: 527 VNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELT 586
V C P + + + +GS +++C ++L G +C DG WS +P C
Sbjct: 305 VLCTPPPLISFGVPIPSSALHFGSTVKYSCVGGFFLRGNSTTLCQPDGTWSSPLPECVPV 364
Query: 587 SCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDC 646
CP+PE G ++ ST + C+ G +L+G +C ++G W G PTC+ I+C
Sbjct: 365 ECPQPEEIPNGIIDVRGLAYLSTALYTCKPGFELVGNTTTLCGENGHWLGGKPTCKAIEC 424
Query: 647 GKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRC 706
K + G + H G + YSC +RL GP TC E W +P C I C
Sbjct: 425 LKPKEILNGKFSYTD--LHYGQTVTYSCNRGFRLEGPSALTCLETGDWDVDAPSCNAIHC 482
Query: 707 SDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLST 766
P E V G Y GA++ Y C G++V G ++ T
Sbjct: 483 DSPQPIENGFVE---------------------GADYSYGAIIIYSCFPGFQVAGHAMQT 521
Query: 767 CEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRM 826
CE++G WS + PTC +DCG P I+ G T + Y F Q D+ E+ V
Sbjct: 522 CEESG-WSSSIPTCMPIDCGLPPHIDFGDCTKLKDDQGY----FEQEDDMMEVPYVTPHP 576
Query: 827 CQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQT 886
G + KE P+ +S G Y C GY L G+
Sbjct: 577 PYHLGAVAKTWENTKE----SPATH----------SSNFLYGTMVSYTCNPGYELLGNPV 622
Query: 887 RTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFL 946
C G NG+ P CI I+C P ENG + + T GS+V+Y C + VG L
Sbjct: 623 LICQEDGTRNGSAPSCISIECDLPTAPENGFLRFT--ETSMGSAVQYSCKPGHILVGSGL 680
Query: 947 RKCLDDGRWSGEEPSCE 963
R CL++ +WSG P CE
Sbjct: 681 RLCLENRKWSGASPRCE 697
Score = 282 bits (692), Expect = 4e-75
Identities = 175/586 (29%), Positives = 254/586 (43%), Gaps = 38/586 (6%)
Query: 372 GSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRTTH 431
G+ + Y C G+ LLG+ C++DG +G+ PSC + C T E+G + + T+
Sbjct: 604 GTMVSYTCNPGYELLGNPVLICQEDGTRNGSAPSCISIECDLPTAPENGFLRFTE--TSM 661
Query: 432 GARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGS 491
G+ YSC+ LVG+ R C + W G +PRC C P V N S+ + + S
Sbjct: 662 GSAVQYSCKPGHILVGSGLRLCLENRKWSGASPRCEAISCKKPNPVMNGSIKGSNYTYLS 721
Query: 492 LASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTIHKGSFVLINGTTTYGSI 551
Y C+ G++L+G+ TC W P C V+ +P + V T+
Sbjct: 722 TLYYECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDRSSPPVSANGQVR-GDEYTFQKE 780
Query: 552 AQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFDYYVHSTIN 611
++TC + L GA VC +G WS P C C P + G E DY +
Sbjct: 781 IEYTCNEGFLLEGARSRVCLANGSWSGATPDCVPVRCATPPQLANGVTEGLDYGFMKEVT 840
Query: 612 FHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHL-GSVI 670
FHC G+ L G P L CQ DG W + P C+ ++CG L +G NG + + G I
Sbjct: 841 FHCHEGYILHGAPKLTCQSDGNWDAEIPLCKPVNCGPPEDLAHG---FPNGFSFIHGGHI 897
Query: 671 QYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTL 730
QY C Y+L G R C WS SSP C RCS P++ +V G D
Sbjct: 898 QYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCLPFRCSTPVI---EYGTVNGTD------- 947
Query: 731 IRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGR 790
D G RI +C KG+K++G S TCE +GQWS P C++ CG+
Sbjct: 948 ------FDCGKAARI------QCFKGFKLLGLSEITCEADGQWSSGFPHCEHTSCGSLPM 995
Query: 791 IENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSA 850
I N ++ +++ Y C + ++G +C E G WS P+C+ ++C P +
Sbjct: 996 IPNAFIS--ETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPLSCGSPPS 1053
Query: 851 QIKAGSGLLVVTSTLSIGGEAHYQCERGYNL-KGHQTRTCISKGQWNGTVPVCIPIDCRS 909
A + + E +C GY + T TC G+W C P C
Sbjct: 1054 VANA----VATGEAHTYESEVKLRCLEGYTMDTDTDTFTCQKDGRWFPERISCSPKKCPL 1109
Query: 910 PGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRW 955
P NI + I++ V C Y G + C DG W
Sbjct: 1110 PENITH--ILVHGDDFSVNRQVSVSCAEGYTFEGVNISVCQLDGTW 1153
Score = 275 bits (675), Expect = 5e-73
Identities = 182/621 (29%), Positives = 268/621 (43%), Gaps = 43/621 (6%)
Query: 349 LPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKY 408
+P SP N + G++Y I Y C EG +L G +SR C +G WSGA P C
Sbjct: 755 IPVDRSSPPVSANGQVRGDEYTFQKEIEYTCNEGFLLEGARSRVCLANGSWSGATPDCVP 814
Query: 409 VNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLF 468
V C + +G +D + C E + L G P+ TC +G WD E P C
Sbjct: 815 VRCATPPQLANGVTEGLDYGFMK--EVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCKP 872
Query: 469 DWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVN 528
C P +++ G Y C G+ L G++S C G+WSG PSC
Sbjct: 873 VNCGPPEDLAHGFPNGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCLPFR 932
Query: 529 CGTPTIHKGSFVLINGTT-TYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTS 587
C TP I G+ +NGT G A+ C + L G E+ C DG+WS P CE TS
Sbjct: 933 CSTPVIEYGT---VNGTDFDCGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHCEHTS 989
Query: 588 CPE-PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDC 646
C P +P+ ++ + + I + C +G+ + G +L+C + G WS P CE + C
Sbjct: 990 CGSLPMIPN-AFISETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPLSC 1048
Query: 647 GKLPTLPYGTMELLNGTTH-LGSVIQYSCTTNYRL-VGPVRRTCTEEFQWSDSSPRCEEI 704
G P++ + G H S ++ C Y + TC ++ +W C
Sbjct: 1049 GSPPSV---ANAVATGEAHTYESEVKLRCLEGYTMDTDTDTFTCQKDGRWFPERISCSPK 1105
Query: 705 RCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESL 764
+C P ++T H L+ G+ + + V C +GY G ++
Sbjct: 1106 KCPLP-------ENIT-------HILVH-------GDDFSVNRQVSVSCAEGYTFEGVNI 1144
Query: 765 STCEDNGQWSG--TTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGV 822
S C+ +G W + +C V CG P E+G V + S TF +T YQC+ +ELEG
Sbjct: 1145 SVCQLDGTWEPPFSDESCSPVSCGKPESPEHGFV-VGSKYTF-ESTIIYQCEPGYELEGN 1202
Query: 823 IRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLK 882
R+CQEN WS ICKE C Q++ +G + + + G Y C RGY+L+
Sbjct: 1203 RERVCQENRQWSGGVAICKETRC---ETQLEFLNGKADIENR-TTGPNVVYSCNRGYSLE 1258
Query: 883 GHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRV 942
G C G W+ VP+C P C P I + +S +V C +
Sbjct: 1259 GPSEAHCTENGTWSHPVPLCKPNPCPVPFVIPENAL-LSEKEFYVDQNVSIKCREGFLLQ 1317
Query: 943 GPFLRKCLDDGRWSGEEPSCE 963
G + D W+ CE
Sbjct: 1318 GHGIITYNPDETWTQTSAKCE 1338
Score = 268 bits (656), Expect = 1e-70
Identities = 157/507 (30%), Positives = 243/507 (47%), Gaps = 39/507 (7%)
Query: 464 PRCLFDWCPDPPAVSNA---SVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGV 520
PRC+ +C PP+VS + SV+ AGS+ S+ C G +L+ S + C GG W+
Sbjct: 2 PRCIAHFCEKPPSVSYSILESVSKAKFAAGSVVSFKCMEGFVLNTSAKIECMRGGQWNPS 61
Query: 521 PPS--CKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSY 578
P S C V CG P + ++G++ ++C +++ G ++ C G+WS
Sbjct: 62 PMSIQCIPVRCGEPPSIMNGYA-SGSNYSFGAMVAYSCNKGFYIKGEKKSTCEASGQWSS 120
Query: 579 DIPSCELTSCPEPEVPSGGYME-AFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGD 637
IP+C SC EP G++E S + + C G+K +G P VC + W +
Sbjct: 121 PIPTCHPVSCGEPPKVENGFLEHTTGRIFESEVRYQCNPGYKPVGSPVFVCHANRHWHSE 180
Query: 638 SPTCEY-IDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWS- 695
SP +DCGK P + G M+ N +GS +Q+ C Y LVG TC + +W+
Sbjct: 181 SPLMWVPLDCGKPPPIQNGFMKGEN--FEVGSKVQFFCNEGYELVGDSSWTCQKSGKWNK 238
Query: 696 DSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEK 755
S+P+C +C +P + E +V +++ T +G +V + C++
Sbjct: 239 KSNPKCMPAKCPEPPLLENQLVL------------------KEL--TTEVG-VVTFSCKE 277
Query: 756 GYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDE 815
G+ + G S+ C + QW+ + P C+ V C P I G V +PS+A +G+T Y C
Sbjct: 278 GHVLQGPSVLKCLPSQQWNDSFPVCKIVLCTPPPLISFG-VPIPSSALHFGSTVKYSCVG 336
Query: 816 NWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQC 875
+ L G +CQ +GTWS P C + CP P + +G++ V L+ A Y C
Sbjct: 337 GFFLRGNSTTLCQPDGTWSSPLPECVPVECPQPE---EIPNGIIDVRG-LAYLSTALYTC 392
Query: 876 ERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYC 935
+ G+ L G+ T C G W G P C I+C P I NGK S +G +V Y C
Sbjct: 393 KPGFELVGNTTTLCGENGHWLGGKPTCKAIECLKPKEILNGK--FSYTDLHYGQTVTYSC 450
Query: 936 LSQYQRVGPFLRKCLDDGRWSGEEPSC 962
++ GP CL+ G W + PSC
Sbjct: 451 NRGFRLEGPSALTCLETGDWDVDAPSC 477
Score = 266 bits (652), Expect = 3e-70
Identities = 174/621 (28%), Positives = 251/621 (40%), Gaps = 46/621 (7%)
Query: 349 LPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKY 408
+P C +P +L N G DY + + C EG++L G C+ DG W P CK
Sbjct: 813 VPVRCATPPQLANGVTEGLDYGFMKEVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCKP 872
Query: 409 VNCGGLTPIEDGDVALIDNRT-THGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL 467
VNCG P ED + + HG Y C + L GN R C G W G +P CL
Sbjct: 873 VNCG---PPEDLAHGFPNGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCL 929
Query: 468 FDWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYV 527
C P + +V G A C G L G + +TC G WS P C++
Sbjct: 930 PFRC-STPVIEYGTVNGTDFDCGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHCEHT 988
Query: 528 NCGTPTIHKGSFVLINGTTTYG-SIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELT 586
+CG+ + +F I+ T+++ ++ ++C Y + G+ +L+C G WS P CE
Sbjct: 989 SCGSLPMIPNAF--ISETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPL 1046
Query: 587 SCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPN-LVCQQDGEWSGDSPTCEYID 645
SC P + + S + C G+ + + + CQ+DG W + +C
Sbjct: 1047 SCGSPPSVANAVATGEAHTYESEVKLRCLEGYTMDTDTDTFTCQKDGRWFPERISCSPKK 1106
Query: 646 CGKLPTLPYGTMELLNGTTH-LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSD--SSPRCE 702
C P T L++G + + SC Y G C + W S C
Sbjct: 1107 C---PLPENITHILVHGDDFSVNRQVSVSCAEGYTFEGVNISVCQLDGTWEPPFSDESCS 1163
Query: 703 EIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGE 762
+ C P E HG VG+ Y + + Y+CE GY++ G
Sbjct: 1164 PVSCGKPESPE------------HGFV---------VGSKYTFESTIIYQCEPGYELEGN 1202
Query: 763 SLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGV 822
C++N QWSG C+ C NGK + + T G Y C+ + LEG
Sbjct: 1203 RERVCQENRQWSGGVAICKETRCETQLEFLNGKADIENRTT--GPNVVYSCNRGYSLEGP 1260
Query: 823 IRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLK 882
C ENGTWS P+CK CP P L+ + +C G+ L+
Sbjct: 1261 SEAHCTENGTWSHPVPLCKPNPCPVP---FVIPENALLSEKEFYVDQNVSIKCREGFLLQ 1317
Query: 883 GHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRV 942
GH T W T C I C P ++EN + +G + Y C S Y
Sbjct: 1318 GHGIITYNPDETWTQTSAKCEKISCGPPAHVENA--IARGVHYQYGDMITYSCYSGYMLE 1375
Query: 943 GPFLRK-CLDDGRWSGEEPSC 962
G FLR CL++G W+ P C
Sbjct: 1376 G-FLRSVCLENGTWT-SPPIC 1394
Score = 257 bits (629), Expect = 2e-67
Identities = 162/553 (29%), Positives = 231/553 (41%), Gaps = 37/553 (6%)
Query: 369 YDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPS--CKYVNCGGLTPIEDGDVALID 426
+ GS + +KC EG +L C + G W+ +P S C V CG I +G +
Sbjct: 28 FAAGSVVSFKCMEGFVLNTSAKIECMRGGQWNPSPMSIQCIPVRCGEPPSIMNGYAS--G 85
Query: 427 NRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVT-VN 485
+ + GA YSC + F + G + TC G W P C C +PP V N +
Sbjct: 86 SNYSFGAMVAYSCNKGFYIKGEKKSTCEASGQWSSPIPTCHPVSCGEPPKVENGFLEHTT 145
Query: 486 GHKAGSLASYTCENGHILSGSTSVTCTLGGAW-SGVPPSCKYVNCGTPTIHKGSFVLING 544
G S Y C G+ GS C W S P ++CG P + F +
Sbjct: 146 GRIFESEVRYQCNPGYKPVGSPVFVCHANRHWHSESPLMWVPLDCGKPPPIQNGF-MKGE 204
Query: 545 TTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWS-YDIPSCELTSCPEPEVPSGGYMEAFD 603
GS QF C Y L G C + GKW+ P C CPEP + +
Sbjct: 205 NFEVGSKVQFFCNEGYELVGDSSWTCQKSGKWNKKSNPKCMPAKCPEPPLLENQLVLKEL 264
Query: 604 YYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGT 663
+ F C+ GH L G L C +W+ P C+ + C P + +G + + +
Sbjct: 265 TTEVGVVTFSCKEGHVLQGPSVLKCLPSQQWNDSFPVCKIVLCTPPPLISFG-VPIPSSA 323
Query: 664 THLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGND 723
H GS ++YSC + L G C + WS P C + C P I+ V
Sbjct: 324 LHFGSTVKYSCVGGFFLRGNSTTLCQPDGTWSSPLPECVPVECPQPEEIPNGIIDVR--- 380
Query: 724 RSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYV 783
G Y AL Y C+ G++++G + + C +NG W G PTC+ +
Sbjct: 381 ----------------GLAYLSTAL--YTCKPGFELVGNTTTLCGENGHWLGGKPTCKAI 422
Query: 784 DCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEI 843
+C P I NGK + YG T Y C+ + LEG C E G W ++ P C I
Sbjct: 423 ECLKPKEILNGKFSYTD--LHYGQTVTYSCNRGFRLEGPSALTCLETGDWDVDAPSCNAI 480
Query: 844 TCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCI 903
C P I+ G V + S G Y C G+ + GH +TC G W+ ++P C+
Sbjct: 481 HCDSPQ-PIENG---FVEGADYSYGAIIIYSCFPGFQVAGHAMQTCEESG-WSSSIPTCM 535
Query: 904 PIDCRSPGNIENG 916
PIDC P +I+ G
Sbjct: 536 PIDCGLPPHIDFG 548
Score = 254 bits (621), Expect = 2e-66
Identities = 163/537 (30%), Positives = 229/537 (42%), Gaps = 42/537 (7%)
Query: 431 HGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAG 490
+G Y+C + L+GNP C ++G +G AP C+ C P A N + G
Sbjct: 603 YGTMVSYTCNPGYELLGNPVLICQEDGTRNGSAPSCISIECDLPTAPENGFLRFTETSMG 662
Query: 491 SLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPT-IHKGSFVLINGTT-TY 548
S Y+C+ GHIL GS C WSG P C+ ++C P + GS I G+ TY
Sbjct: 663 SAVQYSCKPGHILVGSGLRLCLENRKWSGASPRCEAISCKKPNPVMNGS---IKGSNYTY 719
Query: 549 GSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFDYYVHS 608
S + C+P Y LNG E C D W D P C P V + G + +Y
Sbjct: 720 LSTLYYECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDRSSPPVSANGQVRGDEYTFQK 779
Query: 609 TINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGS 668
I + C G L G + VC +G WSG +P C + C P L G E L+
Sbjct: 780 EIEYTCNEGFLLEGARSRVCLANGSWSGATPDCVPVRCATPPQLANGVTEGLD--YGFMK 837
Query: 669 VIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGH 728
+ + C Y L G + TC + W P C+ + C P D +HG
Sbjct: 838 EVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCKPVNCGPP------------EDLAHGF 885
Query: 729 TLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNP 788
G ++ G ++Y+C GYK+ G S C NG WSG++P+C C P
Sbjct: 886 ---------PNGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCLPFRCSTP 936
Query: 789 GRIENGKVTLPSNATFY--GATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCP 846
IE G V N T + G A QC + ++L G+ C+ +G WS P C+ +C
Sbjct: 937 -VIEYGTV----NGTDFDCGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHCEHTSC- 990
Query: 847 DPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPID 906
+ + + TS+ Y C GY ++G C KG W+ PVC P+
Sbjct: 991 --GSLPMIPNAFISETSSWK-ENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPLS 1047
Query: 907 CRSPGNIENGKIVISNGSTLFGSSVEYYCLSQY-QRVGPFLRKCLDDGRWSGEEPSC 962
C SP ++ N V + + + S V+ CL Y C DGRW E SC
Sbjct: 1048 CGSPPSVANA--VATGEAHTYESEVKLRCLEGYTMDTDTDTFTCQKDGRWFPERISC 1102
Score = 246 bits (601), Expect = 4e-64
Identities = 144/505 (28%), Positives = 217/505 (42%), Gaps = 31/505 (6%)
Query: 347 QYLPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSC 406
Q +P CG P ++N G++Y G+ + Y C +G + G+K C+ G WS P+C
Sbjct: 66 QCIPVRCGEPPSIMNGYASGSNYSFGAMVAYSCNKGFYIKGEKKSTCEASGQWSSPIPTC 125
Query: 407 KYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRC 466
V+CG +E+G + R + Y C + VG+P C W E+P
Sbjct: 126 HPVSCGEPPKVENGFLEHTTGRIFE-SEVRYQCNPGYKPVGSPVFVCHANRHWHSESPLM 184
Query: 467 LFDW-CPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVP-PSC 524
C PP + N + + GS + C G+ L G +S TC G W+ P C
Sbjct: 185 WVPLDCGKPPPIQNGFMKGENFEVGSKVQFFCNEGYELVGDSSWTCQKSGKWNKKSNPKC 244
Query: 525 KYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCE 584
C P + + VL TT G + F+C+ + L G L C +W+ P C+
Sbjct: 245 MPAKCPEPPLLENQLVLKELTTEVG-VVTFSCKEGHVLQGPSVLKCLPSQQWNDSFPVCK 303
Query: 585 LTSC-PEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEY 643
+ C P P + G + + + ST+ + C G L G +CQ DG WS P C
Sbjct: 304 IVLCTPPPLISFGVPIPSSALHFGSTVKYSCVGGFFLRGNSTTLCQPDGTWSSPLPECVP 363
Query: 644 IDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEE 703
++C + +P G ++ + G +L + + Y+C + LVG C E W P C+
Sbjct: 364 VECPQPEEIPNGIID-VRGLAYLSTAL-YTCKPGFELVGNTTTLCGENGHWLGGKPTCKA 421
Query: 704 IRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGES 763
I C P S T D +G T V Y C +G+++ G S
Sbjct: 422 IECLKPKEILNGKFSYT--DLHYGQT-------------------VTYSCNRGFRLEGPS 460
Query: 764 LSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVI 823
TC + G W P+C + C +P IENG V + YGA Y C +++ G
Sbjct: 461 ALTCLETGDWDVDAPSCNAIHCDSPQPIENGFVEGADYS--YGAIIIYSCFPGFQVAGHA 518
Query: 824 RRMCQENGTWSLEPPICKEITCPDP 848
+ C+E+G WS P C I C P
Sbjct: 519 MQTCEESG-WSSSIPTCMPIDCGLP 542
Score = 235 bits (574), Expect = 8e-61
Identities = 146/502 (29%), Positives = 218/502 (43%), Gaps = 40/502 (7%)
Query: 349 LPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKY 408
LP C +P + T+ G D+D G +C +G LLG C+ DG WS P C++
Sbjct: 929 LPFRCSTP-VIEYGTVNGTDFDCGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHCEH 987
Query: 409 VNCGGLTPIEDGDVALIDNRTTHGARAL-YSCRENFTLVGNPERTCGDEGIWDGEAPRCL 467
+CG L I + A I ++ + YSCR + + G+ + C ++G+W P C
Sbjct: 988 TSCGSLPMIPN---AFISETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCE 1044
Query: 468 FDWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSV-TCTLGGAWSGVPPSCKY 526
C PP+V+NA T H S C G+ + T TC G W SC
Sbjct: 1045 PLSCGSPPSVANAVATGEAHTYESEVKLRCLEGYTMDTDTDTFTCQKDGRWFPERISCSP 1104
Query: 527 VNCGTPTIHKGSFVLINGTT-TYGSIAQFTCEPDYWLNGAEELVCNRDGKWS--YDIPSC 583
C P + +L++G + +C Y G VC DG W + SC
Sbjct: 1105 KKCPLP--ENITHILVHGDDFSVNRQVSVSCAEGYTFEGVNISVCQLDGTWEPPFSDESC 1162
Query: 584 ELTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEY 643
SC +PE P G++ Y STI + CE G++L G VCQ++ +WSG C+
Sbjct: 1163 SPVSCGKPESPEHGFVVGSKYTFESTIIYQCEPGYELEGNRERVCQENRQWSGGVAICKE 1222
Query: 644 IDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEE 703
C G ++ N TT G + YSC Y L GP CTE WS P C+
Sbjct: 1223 TRCETQLEFLNGKADIENRTT--GPNVVYSCNRGYSLEGPSEAHCTENGTWSHPVPLCKP 1280
Query: 704 IRCSDP-IVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGE 762
C P ++ E +++S + + V +C +G+ + G
Sbjct: 1281 NPCPVPFVIPENALLS---------------------EKEFYVDQNVSIKCREGFLLQGH 1319
Query: 763 SLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATF-YGATAFYQCDENWELEG 821
+ T + W+ T+ C+ + CG P +EN + + YG Y C + LEG
Sbjct: 1320 GIITYNPDETWTQTSAKCEKISCGPPAHVEN---AIARGVHYQYGDMITYSCYSGYMLEG 1376
Query: 822 VIRRMCQENGTWSLEPPICKEI 843
+R +C ENGTW+ PPIC+ +
Sbjct: 1377 FLRSVCLENGTWT-SPPICRAV 1397
Score = 159 bits (385), Expect = 7e-38
Identities = 105/390 (26%), Positives = 165/390 (42%), Gaps = 36/390 (9%)
Query: 580 IPSCELTSCPEPEVPSGGYMEAFD---YYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSG 636
+P C C +P S +E+ + S ++F C G L + C + G+W+
Sbjct: 1 MPRCIAHFCEKPPSVSYSILESVSKAKFAAGSVVSFKCMEGFVLNTSAKIECMRGGQWNP 60
Query: 637 D--SPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQW 694
S C + CG+ P++ G N + G+++ YSC + + G + TC QW
Sbjct: 61 SPMSIQCIPVRCGEPPSIMNGYASGSNYS--FGAMVAYSCNKGFYIKGEKKSTCEASGQW 118
Query: 695 SDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCE 754
S P C + C +P E + HT R ++ V+Y+C
Sbjct: 119 SSPIPTCHPVSCGEPPKVENGFLE---------HTTGRIFESE-----------VRYQCN 158
Query: 755 KGYKVIGESLSTCEDNGQWSGTTPTCQY-VDCGNPGRIENGKVTLPSNATFYGATAFYQC 813
GYK +G + C N W +P +DCG P I+NG + G+ + C
Sbjct: 159 PGYKPVGSPVFVCHANRHWHSESPLMWVPLDCGKPPPIQNG--FMKGENFEVGSKVQFFC 216
Query: 814 DENWELEGVIRRMCQENGTWSLEP-PICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAH 872
+E +EL G CQ++G W+ + P C CP+P LV+ + G
Sbjct: 217 NEGYELVGDSSWTCQKSGKWNKKSNPKCMPAKCPEPPLL----ENQLVLKELTTEVGVVT 272
Query: 873 YQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVE 932
+ C+ G+ L+G C+ QWN + PVC + C P I G + I + + FGS+V+
Sbjct: 273 FSCKEGHVLQGPSVLKCLPSQQWNDSFPVCKIVLCTPPPLISFG-VPIPSSALHFGSTVK 331
Query: 933 YYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
Y C+ + G C DG WS P C
Sbjct: 332 YSCVGGFFLRGNSTTLCQPDGTWSSPLPEC 361
Score = 146 bits (354), Expect = 4e-34
Identities = 98/331 (29%), Positives = 150/331 (45%), Gaps = 33/331 (9%)
Query: 639 PTCEYIDCGKLPTLPYGTMELLNGTTHL-GSVIQYSCTTNYRLVGPVRRTCTEEFQWSDS 697
P C C K P++ Y +E ++ GSV+ + C + L + C QW+ S
Sbjct: 2 PRCIAHFCEKPPSVSYSILESVSKAKFAAGSVVSFKCMEGFVLNTSAKIECMRGGQWNPS 61
Query: 698 --SPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEK 755
S +C +RC +P SI++ G+ G+ Y GA+V Y C K
Sbjct: 62 PMSIQCIPVRCGEP----PSIMN--------GYAS---------GSNYSFGAMVAYSCNK 100
Query: 756 GYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDE 815
G+ + GE STCE +GQWS PTC V CG P ++ENG + + F YQC+
Sbjct: 101 GFYIKGEKKSTCEASGQWSSPIPTCHPVSCGEPPKVENGFLEHTTGRIFESEVR-YQCNP 159
Query: 816 NWELEGVIRRMCQENGTWSLEPPIC-KEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQ 874
++ G +C N W E P+ + C P I+ G + +G + +
Sbjct: 160 GYKPVGSPVFVCHANRHWHSESPLMWVPLDCGKP-PPIQNG---FMKGENFEVGSKVQFF 215
Query: 875 CERGYNLKGHQTRTCISKGQWN-GTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEY 933
C GY L G + TC G+WN + P C+P C P +EN ++V+ +T G V +
Sbjct: 216 CNEGYELVGDSSWTCQKSGKWNKKSNPKCMPAKCPEPPLLEN-QLVLKELTTEVG-VVTF 273
Query: 934 YCLSQYQRVGPFLRKCLDDGRWSGEEPSCEL 964
C + GP + KCL +W+ P C++
Sbjct: 274 SCKEGHVLQGPSVLKCLPSQQWNDSFPVCKI 304
Score = 145 bits (352), Expect = 7e-34
Identities = 101/369 (27%), Positives = 143/369 (38%), Gaps = 13/369 (3%)
Query: 345 ICQYLPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRH-CKKDGFWSGAP 403
+C+ P +CGSP + N G + S + +C EG+ + D C+KDG W
Sbjct: 1042 VCE--PLSCGSPPSVANAVATGEAHTYESEVKLRCLEGYTMDTDTDTFTCQKDGRWFPER 1099
Query: 404 PSCKYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDG-- 461
SC C P + + + + + SC E +T G C +G W+
Sbjct: 1100 ISCSPKKCP--LPENITHILVHGDDFSVNRQVSVSCAEGYTFEGVNISVCQLDGTWEPPF 1157
Query: 462 EAPRCLFDWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVP 521
C C P + + V + + S Y CE G+ L G+ C WSG
Sbjct: 1158 SDESCSPVSCGKPESPEHGFVVGSKYTFESTIIYQCEPGYELEGNRERVCQENRQWSGGV 1217
Query: 522 PSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIP 581
CK C T I TT G ++C Y L G E C +G WS+ +P
Sbjct: 1218 AICKETRCETQLEFLNGKADIENRTT-GPNVVYSCNRGYSLEGPSEAHCTENGTWSHPVP 1276
Query: 582 SCELTSCPEPEV-PSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPT 640
C+ CP P V P + ++YV ++ C G L G + D W+ S
Sbjct: 1277 LCKPNPCPVPFVIPENALLSEKEFYVDQNVSIKCREGFLLQGHGIITYNPDETWTQTSAK 1336
Query: 641 CEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPR 700
CE I CG P G +I YSC + Y L G +R C E W+ S P
Sbjct: 1337 CEKISCG--PPAHVENAIARGVHYQYGDMITYSCYSGYMLEGFLRSVCLENGTWT-SPPI 1393
Query: 701 CEEIRCSDP 709
C + C P
Sbjct: 1394 CRAV-CRFP 1401
Score = 40.7 bits (91), Expect = 0.028
Identities = 17/43 (39%), Positives = 20/43 (46%)
Query: 19 ENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTN 61
EN G VY C+ GY L G + CT G W+ P C N
Sbjct: 1239 ENRTTGPNVVYSCNRGYSLEGPSEAHCTENGTWSHPVPLCKPN 1281
Score = 37.1 bits (82), Expect = 0.34
Identities = 16/58 (27%), Positives = 26/58 (44%), Gaps = 3/58 (5%)
Query: 1 RCGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
RCG P P+ + N G + Y C++G+ + G ++ C G W+ P C
Sbjct: 71 RCGEP---PSIMNGYASGSNYSFGAMVAYSCNKGFYIKGEKKSTCEASGQWSSPIPTC 125
Score = 37.1 bits (82), Expect = 0.34
Identities = 16/51 (31%), Positives = 22/51 (43%)
Query: 8 PPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
P + PN + + G Y+C GY+L G R C G W+ P C
Sbjct: 878 PEDLAHGFPNGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSC 928
Score = 35.5 bits (78), Expect = 1.0
Identities = 17/48 (35%), Positives = 22/48 (45%)
Query: 29 YECDEGYELFGARQRECTLRGDWTLEPPFCGTNVAFRKPANQSTTVRG 76
YECD GY L G +R C +W + P C P + + VRG
Sbjct: 725 YECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDRSSPPVSANGQVRG 772
Score = 35.5 bits (78), Expect = 1.0
Identities = 14/30 (46%), Positives = 17/30 (56%)
Query: 29 YECDEGYELFGARQRECTLRGDWTLEPPFC 58
Y C+EG+ L GAR R C G W+ P C
Sbjct: 783 YTCNEGFLLEGARSRVCLANGSWSGATPDC 812
Score = 34.7 bits (76), Expect = 1.8
Identities = 21/57 (36%), Positives = 24/57 (42%), Gaps = 4/57 (7%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
CG PA NA I + G + Y C GY L G + C G WT PP C
Sbjct: 1342 CGPPAHVENA---IARGVHYQYGDMITYSCYSGYMLEGFLRSVCLENGTWT-SPPIC 1394
Score = 34.3 bits (75), Expect = 2.4
Identities = 18/57 (31%), Positives = 26/57 (45%), Gaps = 3/57 (5%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
CG + PNA +S E + + Y C GY + G+ CT +G W+ P C
Sbjct: 990 CGSLPMIPNAFIS---ETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVC 1043
Score = 34.3 bits (75), Expect = 2.4
Identities = 18/51 (35%), Positives = 25/51 (49%), Gaps = 3/51 (5%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWT 52
CG P P + V + TI +Y+C+ GYEL G R+R C W+
Sbjct: 1167 CGKPESPEHGFVV--GSKYTFESTI-IYQCEPGYELEGNRERVCQENRQWS 1214
Score = 33.5 bits (73), Expect = 4.2
Identities = 12/35 (34%), Positives = 16/35 (45%)
Query: 24 GTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
G Y C+ G+ L G C GDW ++ P C
Sbjct: 443 GQTVTYSCNRGFRLEGPSALTCLETGDWDVDAPSC 477
Score = 33.5 bits (73), Expect = 4.2
Identities = 13/30 (43%), Positives = 16/30 (53%)
Query: 29 YECDEGYELFGARQRECTLRGDWTLEPPFC 58
+ C EGY L GA + C G+W E P C
Sbjct: 841 FHCHEGYILHGAPKLTCQSDGNWDAEIPLC 870
Score = 33.1 bits (72), Expect = 5.6
Identities = 15/44 (34%), Positives = 19/44 (43%)
Query: 8 PPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDW 51
PP + EN G+ + C+EGYEL G C G W
Sbjct: 193 PPPIQNGFMKGENFEVGSKVQFFCNEGYELVGDSSWTCQKSGKW 236
>AB212622-1|BAD97692.1| 3631|Homo sapiens CSMD2 protein protein.
Length = 3631
Score = 295 bits (723), Expect = 7e-79
Identities = 183/642 (28%), Positives = 289/642 (45%), Gaps = 47/642 (7%)
Query: 337 CNLDYLHWICQY---LPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHC 393
C D+ HW + +P TCG P +N GN +++ + + C G+M G C
Sbjct: 2779 CQQDH-HWSGKTPFCVPITCGHPGNPVNGLTQGNQFNLNDVVKFVCNPGYMAEGAARSQC 2837
Query: 394 KKDGFWSGAPPSCKYVNCGGLTPIEDG--DV-ALIDNRTTHGARALYSCRENFTLVGNPE 450
G WS P+C+ +NC E+ V A +R + G Y C F L+G P
Sbjct: 2838 LASGQWSDMLPTCRIINCTDPGHQENSVRQVHASGPHRFSFGTTVSYRCNHGFYLLGTPV 2897
Query: 451 RTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVT 510
+C +G WD P+CL C P + ++ ++ + + G++ Y+C L G+++
Sbjct: 2898 LSCQGDGTWDRPRPQCLLVSCGHPGSPPHSQMSGDSYTVGAVVRYSCIGKRTLVGNSTRM 2957
Query: 511 CTLGGAWSGVPPSCKYVN---CGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEE 567
C L G W+G P C + CG P I + + + G++ +F+CE + L G+ E
Sbjct: 2958 CGLDGHWTGSLPHCSGTSVGVCGDPGI-PAHGIRLGDSFDPGTVMRFSCEAGHVLRGSSE 3016
Query: 568 LVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFDYYV-HSTINFHCEAGHKLIGEPNL 626
C +G WS P C + SC P PS + D V S+I + C G+ G +
Sbjct: 3017 RTCQANGSWSGSQPECGVISCGNPGTPSNARVVFSDGLVFSSSIVYECREGYYATGLLSR 3076
Query: 627 VCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVG--PV 684
C +G W+G P C I+CG P +P + L N + + Y C Y +
Sbjct: 3077 HCSVNGTWTGSDPECLVINCGD-PGIPANGLRLGNDFRY-NKTVTYQCVPGYMMESHRVS 3134
Query: 685 RRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYR 744
+CT++ W+ + P C+ + C P LI + + VG+ +
Sbjct: 3135 VLSCTKDRTWNGTKPVCKALMCKPP-------------------PLI--PNGKVVGSDFM 3173
Query: 745 IGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATF 804
G+ V Y C +GY++ ++ TCE NG W+G P C V CG+PG G+
Sbjct: 3174 WGSSVTYACLEGYQLSLPAVFTCEGNGSWTGELPQCFPVFCGDPGVPSRGR--REDRGFS 3231
Query: 805 YGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKE---ITCPDPSAQIKAGSGLLVV 861
Y ++ + C L G RR CQ +GTWS P C + TC DP G+
Sbjct: 3232 YRSSVSFSCHPPLVLVGSPRRFCQSDGTWSGTQPSCIDPTLTTCADPGV---PQFGIQNN 3288
Query: 862 TSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVIS 921
+ +G ++C++GY L+G TRTC+ W+GT P C+P CR P + +
Sbjct: 3289 SQGYQVGSTVLFRCQKGYLLQGSTTRTCLPNLTWSGTPPDCVPHHCRQPETPTHANVGAL 3348
Query: 922 NGSTLFGSSVEYYCLSQYQ-RVGPFLRKCLDDGRWSGEEPSC 962
+ ++ G ++ Y C + + G R C DG W+G+ P C
Sbjct: 3349 DLPSM-GYTLIYSCQEGFSLKGGSEHRTCKADGSWTGKPPIC 3389
Score = 275 bits (675), Expect = 5e-73
Identities = 181/623 (29%), Positives = 257/623 (41%), Gaps = 45/623 (7%)
Query: 353 CGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCG 412
CG+P+ ++N I G +Y +VY+C G L+G R C++D WSG P C + CG
Sbjct: 2739 CGTPEPIVNGHINGENYSYRGSVVYQCNAGFRLIGMSVRICQQDHHWSGKTPFCVPITCG 2798
Query: 413 GLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCP 472
P + N+ + C + G C G W P C C
Sbjct: 2799 --HPGNPVNGLTQGNQFNLNDVVKFVCNPGYMAEGAARSQCLASGQWSDMLPTCRIINCT 2856
Query: 473 DPPAVSNA--SVTVNG-HK--AGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYV 527
DP N+ V +G H+ G+ SY C +G L G+ ++C G W P C V
Sbjct: 2857 DPGHQENSVRQVHASGPHRFSFGTTVSYRCNHGFYLLGTPVLSCQGDGTWDRPRPQCLLV 2916
Query: 528 NCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTS 587
+CG P S + + T G++ +++C L G +C DG W+ +P C TS
Sbjct: 2917 SCGHPGSPPHS-QMSGDSYTVGAVVRYSCIGKRTLVGNSTRMCGLDGHWTGSLPHCSGTS 2975
Query: 588 ---CPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYI 644
C +P +P+ G + + + F CEAGH L G CQ +G WSG P C I
Sbjct: 2976 VGVCGDPGIPAHGIRLGDSFDPGTVMRFSCEAGHVLRGSSERTCQANGSWSGSQPECGVI 3035
Query: 645 DCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEI 704
CG P P + + S I Y C Y G + R C+ W+ S P C I
Sbjct: 3036 SCGN-PGTPSNARVVFSDGLVFSSSIVYECREGYYATGLLSRHCSVNGTWTGSDPECLVI 3094
Query: 705 RCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESL 764
C DP + + +GN +R V Y+C GY + +
Sbjct: 3095 NCGDPGIPANGL---------------------RLGNDFRYNKTVTYQCVPGYMMESHRV 3133
Query: 765 S--TCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGV 822
S +C + W+GT P C+ + C P I NGKV + +G++ Y C E ++L
Sbjct: 3134 SVLSCTKDRTWNGTKPVCKALMCKPPPLIPNGKVV--GSDFMWGSSVTYACLEGYQLSLP 3191
Query: 823 IRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLK 882
C+ NG+W+ E P C + C DP + S + C L
Sbjct: 3192 AVFTCEGNGSWTGELPQCFPVFCGDPGVPSRGRR----EDRGFSYRSSVSFSCHPPLVLV 3247
Query: 883 GHQTRTCISKGQWNGTVPVCIP---IDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQY 939
G R C S G W+GT P CI C PG + G S G + GS+V + C Y
Sbjct: 3248 GSPRRFCQSDGTWSGTQPSCIDPTLTTCADPGVPQFGIQNNSQGYQV-GSTVLFRCQKGY 3306
Query: 940 QRVGPFLRKCLDDGRWSGEEPSC 962
G R CL + WSG P C
Sbjct: 3307 LLQGSTTRTCLPNLTWSGTPPDC 3329
Score = 275 bits (675), Expect = 5e-73
Identities = 160/546 (29%), Positives = 242/546 (44%), Gaps = 38/546 (6%)
Query: 369 YDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNR 428
+ G+ + Y+C G LLG C+ DG W P C V+CG P + +
Sbjct: 2876 FSFGTTVSYRCNHGFYLLGTPVLSCQGDGTWDRPRPQCLLVSCGH--PGSPPHSQMSGDS 2933
Query: 429 TTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL---FDWCPDPPAVSNASVTVN 485
T GA YSC TLVGN R CG +G W G P C C DP ++ +
Sbjct: 2934 YTVGAVVRYSCIGKRTLVGNSTRMCGLDGHWTGSLPHCSGTSVGVCGDPGIPAHGIRLGD 2993
Query: 486 GHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTIHKGSFVLINGT 545
G++ ++CE GH+L GS+ TC G+WSG P C ++CG P + V+ +
Sbjct: 2994 SFDPGTVMRFSCEAGHVLRGSSERTCQANGSWSGSQPECGVISCGNPGTPSNARVVFSDG 3053
Query: 546 TTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFDYY 605
+ S + C Y+ G C+ +G W+ P C + +C +P +P+ G D+
Sbjct: 3054 LVFSSSIVYECREGYYATGLLSRHCSVNGTWTGSDPECLVINCGDPGIPANGLRLGNDFR 3113
Query: 606 VHSTINFHCEAGHKLIGE--PNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGT 663
+ T+ + C G+ + L C +D W+G P C+ + C P +P G +++
Sbjct: 3114 YNKTVTYQCVPGYMMESHRVSVLSCTKDRTWNGTKPVCKALMCKPPPLIPNG--KVVGSD 3171
Query: 664 THLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGND 723
GS + Y+C Y+L P TC W+ P+C + C DP V
Sbjct: 3172 FMWGSSVTYACLEGYQLSLPAVFTCEGNGSWTGELPQCFPVFCGDPGVP----------- 3220
Query: 724 RSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTC--- 780
S G D G +YR + V + C ++G C+ +G WSGT P+C
Sbjct: 3221 -SRGR-------REDRGFSYR--SSVSFSCHPPLVLVGSPRRFCQSDGTWSGTQPSCIDP 3270
Query: 781 QYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPIC 840
C +PG + G + S G+T ++C + + L+G R C N TWS PP C
Sbjct: 3271 TLTTCADPGVPQFG-IQNNSQGYQVGSTVLFRCQKGYLLQGSTTRTCLPNLTWSGTPPDC 3329
Query: 841 KEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLK-GHQTRTCISKGQWNGTV 899
C P A G L + S+G Y C+ G++LK G + RTC + G W G
Sbjct: 3330 VPHHCRQPETPTHANVGALDLP---SMGYTLIYSCQEGFSLKGGSEHRTCKADGSWTGKP 3386
Query: 900 PVCIPI 905
P+C+ +
Sbjct: 3387 PICLEV 3392
Score = 271 bits (664), Expect = 1e-71
Identities = 188/660 (28%), Positives = 281/660 (42%), Gaps = 72/660 (10%)
Query: 347 QYLPPTCGSPDKLLNTTILGN-DYDVGSRIVYKCPEGHMLLGDKSRHCKK--DGF--WSG 401
+Y P C P L+ ILG G I + C G+ L+G C + G+ WS
Sbjct: 2460 RYSAPYCSLPRAPLHGFILGQTSTQPGGSIHFGCNAGYRLVGHSMAICTRHPQGYHLWSE 2519
Query: 402 APPSCKYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERT--CGDEGIW 459
A P C+ ++CG P + + T G +A+YSC E + L E T C D G+W
Sbjct: 2520 AIPLCQALSCG--LPEAPKNGMVFGKEYTVGTKAVYSCSEGYHLQAGAEATAECLDTGLW 2577
Query: 460 DGE--APRCLFDWCPDPPAVSNAS-----VTVNGHKAGSLASYTCENGHILSGSTSVTCT 512
P+C+ CPD ++S + ++ + C+ G+ +G + C
Sbjct: 2578 SNRNVPPQCVPVTCPDVSSISVEHGRWRLIFETQYQFQAQLMLICDPGYYYTGQRVIRCQ 2637
Query: 513 LGGAWS--GVPPSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVC 570
G WS P+C+ ++CG I I + YG+ A F+C Y L G+ C
Sbjct: 2638 ANGKWSLGDSTPTCRIISCGELPIPPNGH-RIGTLSVYGATAIFSCNSGYTLVGSRVREC 2696
Query: 571 NRDGKWS---------------------YDI-PSCELTS---CPEPEVPSGGYMEAFDYY 605
+G WS +D+ S LT C PE G++ +Y
Sbjct: 2697 MANGLWSGSEVRCLATQTKLHSIFYKLLFDVLSSPSLTKAGHCGTPEPIVNGHINGENYS 2756
Query: 606 VHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTH 665
++ + C AG +LIG +CQQD WSG +P C I CG P P + N +
Sbjct: 2757 YRGSVVYQCNAGFRLIGMSVRICQQDHHWSGKTPFCVPITCGH-PGNPVNGLTQGN-QFN 2814
Query: 666 LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRS 725
L V+++ C Y G R C QWSD P C I C+DP E S+ V +
Sbjct: 2815 LNDVVKFVCNPGYMAEGAARSQCLASGQWSDMLPTCRIINCTDPGHQENSVRQVHASG-- 2872
Query: 726 HGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDC 785
+ + G V YRC G+ ++G + +C+ +G W P C V C
Sbjct: 2873 --------------PHRFSFGTTVSYRCNHGFYLLGTPVLSCQGDGTWDRPRPQCLLVSC 2918
Query: 786 GNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEIT- 844
G+PG + +++ ++ GA Y C L G RMC +G W+ P C +
Sbjct: 2919 GHPGSPPHSQMS--GDSYTVGAVVRYSCIGKRTLVGNSTRMCGLDGHWTGSLPHCSGTSV 2976
Query: 845 --CPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVC 902
C DP + + + G + CE G+ L+G RTC + G W+G+ P C
Sbjct: 2977 GVCGDPGIPAHG----IRLGDSFDPGTVMRFSCEAGHVLRGSSERTCQANGSWSGSQPEC 3032
Query: 903 IPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
I C +PG N ++V S+G +F SS+ Y C Y G R C +G W+G +P C
Sbjct: 3033 GVISCGNPGTPSNARVVFSDG-LVFSSSIVYECREGYYATGLLSRHCSVNGTWTGSDPEC 3091
Score = 268 bits (656), Expect = 1e-70
Identities = 177/624 (28%), Positives = 255/624 (40%), Gaps = 64/624 (10%)
Query: 372 GSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSC------------------------- 406
G+ ++ C G+ L+G + R C +G WSG+ C
Sbjct: 2675 GATAIFSCNSGYTLVGSRVRECMANGLWSGSEVRCLATQTKLHSIFYKLLFDVLSSPSLT 2734
Query: 407 KYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRC 466
K +CG PI +G + +N + G+ +Y C F L+G R C + W G+ P C
Sbjct: 2735 KAGHCGTPEPIVNGHING-ENYSYRGS-VVYQCNAGFRLIGMSVRICQQDHHWSGKTPFC 2792
Query: 467 LFDWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKY 526
+ C P N N + + C G++ G+ C G WS + P+C+
Sbjct: 2793 VPITCGHPGNPVNGLTQGNQFNLNDVVKFVCNPGYMAEGAARSQCLASGQWSDMLPTCRI 2852
Query: 527 VNCGTPTIHKGSFVLINGT----TTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPS 582
+NC P + S ++ + ++G+ + C ++L G L C DG W P
Sbjct: 2853 INCTDPGHQENSVRQVHASGPHRFSFGTTVSYRCNHGFYLLGTPVLSCQGDGTWDRPRPQ 2912
Query: 583 CELTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCE 642
C L SC P P M Y V + + + C L+G +C DG W+G P C
Sbjct: 2913 CLLVSCGHPGSPPHSQMSGDSYTVGAVVRYSCIGKRTLVGNSTRMCGLDGHWTGSLPHCS 2972
Query: 643 YIDCGKL--PTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPR 700
G P +P + L + G+V+++SC + L G RTC WS S P
Sbjct: 2973 GTSVGVCGDPGIPAHGIR-LGDSFDPGTVMRFSCEAGHVLRGSSERTCQANGSWSGSQPE 3031
Query: 701 CEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVI 760
C I C +P S V +D L+ +S + Y C +GY
Sbjct: 3032 CGVISCGNP--GTPSNARVVFSD-----GLVFSSS-------------IVYECREGYYAT 3071
Query: 761 GESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELE 820
G C NG W+G+ P C ++CG+PG NG + L N Y T YQC + +E
Sbjct: 3072 GLLSRHCSVNGTWTGSDPECLVINCGDPGIPANG-LRL-GNDFRYNKTVTYQCVPGYMME 3129
Query: 821 G--VIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERG 878
V C ++ TW+ P+CK + C P I G VV S G Y C G
Sbjct: 3130 SHRVSVLSCTKDRTWNGTKPVCKALMCKPPPL-IPNGK---VVGSDFMWGSSVTYACLEG 3185
Query: 879 YNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQ 938
Y L TC G W G +P C P+ C PG G+ + + SSV + C
Sbjct: 3186 YQLSLPAVFTCEGNGSWTGELPQCFPVFCGDPGVPSRGR--REDRGFSYRSSVSFSCHPP 3243
Query: 939 YQRVGPFLRKCLDDGRWSGEEPSC 962
VG R C DG WSG +PSC
Sbjct: 3244 LVLVGSPRRFCQSDGTWSGTQPSC 3267
Score = 228 bits (557), Expect = 1e-58
Identities = 177/663 (26%), Positives = 264/663 (39%), Gaps = 77/663 (11%)
Query: 345 ICQYLPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEG-HMLLG-DKSRHCKKDGFWSG- 401
+CQ L +CG P+ N + G +Y VG++ VY C EG H+ G + + C G WS
Sbjct: 2523 LCQAL--SCGLPEAPKNGMVFGKEYTVGTKAVYSCSEGYHLQAGAEATAECLDTGLWSNR 2580
Query: 402 -APPSCKYVNCGGLTPI--EDGDVALI-DNRTTHGARALYSCRENFTLVGNPERTCGDEG 457
PP C V C ++ I E G LI + + A+ + C + G C G
Sbjct: 2581 NVPPQCVPVTCPDVSSISVEHGRWRLIFETQYQFQAQLMLICDPGYYYTGQRVIRCQANG 2640
Query: 458 IWD-GEA-PRCLFDWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGG 515
W G++ P C C + P N G+ A ++C +G+ L GS C G
Sbjct: 2641 KWSLGDSTPTCRIISCGELPIPPNGHRIGTLSVYGATAIFSCNSGYTLVGSRVRECMANG 2700
Query: 516 AWSGVPPSC-------------------------KYVNCGTPT-IHKGSFVLINGTT-TY 548
WSG C K +CGTP I G ING +Y
Sbjct: 2701 LWSGSEVRCLATQTKLHSIFYKLLFDVLSSPSLTKAGHCGTPEPIVNGH---INGENYSY 2757
Query: 549 GSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFDYYVHS 608
+ C + L G +C +D WS P C +C P P G + + ++
Sbjct: 2758 RGSVVYQCNAGFRLIGMSVRICQQDHHWSGKTPFCVPITCGHPGNPVNGLTQGNQFNLND 2817
Query: 609 TINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTH--- 665
+ F C G+ G C G+WS PTC I+C ++ H
Sbjct: 2818 VVKFVCNPGYMAEGAARSQCLASGQWSDMLPTCRIINCTDPGHQENSVRQVHASGPHRFS 2877
Query: 666 LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRS 725
G+ + Y C + L+G +C + W P+C + C P S +S
Sbjct: 2878 FGTTVSYRCNHGFYLLGTPVLSCQGDGTWDRPRPQCLLVSCGHPGSPPHSQMS------- 2930
Query: 726 HGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVD- 784
G++Y +GA+V+Y C ++G S C +G W+G+ P C
Sbjct: 2931 --------------GDSYTVGAVVRYSCIGKRTLVGNSTRMCGLDGHWTGSLPHCSGTSV 2976
Query: 785 --CGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKE 842
CG+PG +G + L ++ G + C+ L G R CQ NG+WS P C
Sbjct: 2977 GVCGDPGIPAHG-IRL-GDSFDPGTVMRFSCEAGHVLRGSSERTCQANGSWSGSQPECGV 3034
Query: 843 ITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVC 902
I+C +P A +V + L Y+C GY G +R C G W G+ P C
Sbjct: 3035 ISCGNPGTPSNA---RVVFSDGLVFSSSIVYECREGYYATGLLSRHCSVNGTWTGSDPEC 3091
Query: 903 IPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVG--PFLRKCLDDGRWSGEEP 960
+ I+C PG NG + + N + +V Y C+ Y + C D W+G +P
Sbjct: 3092 LVINCGDPGIPANG-LRLGN-DFRYNKTVTYQCVPGYMMESHRVSVLSCTKDRTWNGTKP 3149
Query: 961 SCE 963
C+
Sbjct: 3150 VCK 3152
Score = 184 bits (449), Expect = 1e-45
Identities = 113/362 (31%), Positives = 160/362 (44%), Gaps = 12/362 (3%)
Query: 352 TCGSPDKLLNTTILGNDYDV-GSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVN 410
+CG+P N ++ +D V S IVY+C EG+ G SRHC +G W+G+ P C +N
Sbjct: 3036 SCGNPGTPSNARVVFSDGLVFSSSIVYECREGYYATGLLSRHCSVNGTWTGSDPECLVIN 3095
Query: 411 CGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPER--TCGDEGIWDGEAPRCLF 468
CG P + + N + Y C + + + +C + W+G P C
Sbjct: 3096 CGD--PGIPANGLRLGNDFRYNKTVTYQCVPGYMMESHRVSVLSCTKDRTWNGTKPVCKA 3153
Query: 469 DWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVN 528
C PP + N V + GS +Y C G+ LS TC G+W+G P C V
Sbjct: 3154 LMCKPPPLIPNGKVVGSDFMWGSSVTYACLEGYQLSLPAVFTCEGNGSWTGELPQCFPVF 3213
Query: 529 CGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSC---EL 585
CG P + G + Y S F+C P L G+ C DG WS PSC L
Sbjct: 3214 CGDPGVPSRGRREDRGFS-YRSSVSFSCHPPLVLVGSPRRFCQSDGTWSGTQPSCIDPTL 3272
Query: 586 TSCPEPEVPSGGYME-AFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYI 644
T+C +P VP G + Y V ST+ F C+ G+ L G C + WSG P C
Sbjct: 3273 TTCADPGVPQFGIQNNSQGYQVGSTVLFRCQKGYLLQGSTTRTCLPNLTWSGTPPDCVPH 3332
Query: 645 DCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVG-PVRRTCTEEFQWSDSSPRCEE 703
C + T + + L+ +G + YSC + L G RTC + W+ P C E
Sbjct: 3333 HCRQPETPTHANVGALD-LPSMGYTLIYSCQEGFSLKGGSEHRTCKADGSWTGKPPICLE 3391
Query: 704 IR 705
+R
Sbjct: 3392 VR 3393
Score = 157 bits (381), Expect = 2e-37
Identities = 154/643 (23%), Positives = 253/643 (39%), Gaps = 46/643 (7%)
Query: 353 CGSPDKLLNTTIL--GNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGF--WSGAPPSCKY 408
C P L N ++ ++++G + Y+C G L+G++ CK + + G PP C+
Sbjct: 2292 CPPPTILPNAEVVTENEEFNIGDIVRYRCLPGFTLVGNEILTCKLGTYLQFEGPPPICE- 2350
Query: 409 VNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCG-DEGIWDGEAPRCL 467
V+C + D ++ +C ++ + P+ + E
Sbjct: 2351 VHCPTNELLTDSTGVILSQSYPGSYPQFQTC--SWLVRVEPDYNISLTVEYFLSEKQYDE 2408
Query: 468 FDWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYV 527
F+ P S ++G+ + L + N L S+ G + S Y
Sbjct: 2409 FEIFDGPSGQSPLLKALSGNYSAPLIVTSSSNSVYLRWSSDHAYNRKGF--KIRYSAPY- 2465
Query: 528 NCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGK----WSYDIPSC 583
C P F+L +T G F C Y L G +C R + WS IP C
Sbjct: 2466 -CSLPRAPLHGFILGQTSTQPGGSIHFGCNAGYRLVGHSMAICTRHPQGYHLWSEAIPLC 2524
Query: 584 ELTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIG--EPNLVCQQDGEWSGDS--P 639
+ SC PE P G + +Y V + + C G+ L E C G WS + P
Sbjct: 2525 QALSCGLPEAPKNGMVFGKEYTVGTKAVYSCSEGYHLQAGAEATAECLDTGLWSNRNVPP 2584
Query: 640 TCEYIDCGKLPTLP--YGTMELLNGTTH-LGSVIQYSCTTNYRLVGPVRRTCTEEFQWS- 695
C + C + ++ +G L+ T + + + C Y G C +WS
Sbjct: 2585 QCVPVTCPDVSSISVEHGRWRLIFETQYQFQAQLMLICDPGYYYTGQRVIRCQANGKWSL 2644
Query: 696 -DSSPRCEEIRCSD-PI------VAEKSIVSVTGN-DRSHGHTLIRTSDNRDVGNTYRIG 746
DS+P C I C + PI + S+ T + G+TL+ + + N G
Sbjct: 2645 GDSTPTCRIISCGELPIPPNGHRIGTLSVYGATAIFSCNSGYTLVGSRVRECMANGLWSG 2704
Query: 747 ALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYG 806
+ V RC + + S + + CG P I NG + N ++ G
Sbjct: 2705 SEV--RCLATQTKLHSIFYKLLFDVLSSPSLTKAGH--CGTPEPIVNGHIN-GENYSYRG 2759
Query: 807 ATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLS 866
+ YQC+ + L G+ R+CQ++ WS + P C ITC P + L + +
Sbjct: 2760 SVV-YQCNAGFRLIGMSVRICQQDHHWSGKTPFCVPITCGHPGNPVNG----LTQGNQFN 2814
Query: 867 IGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENG-KIVISNGST 925
+ + C GY +G C++ GQW+ +P C I+C PG+ EN + V ++G
Sbjct: 2815 LNDVVKFVCNPGYMAEGAARSQCLASGQWSDMLPTCRIINCTDPGHQENSVRQVHASGPH 2874
Query: 926 LF--GSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCELAT 966
F G++V Y C + +G + C DG W P C L +
Sbjct: 2875 RFSFGTTVSYRCNHGFYLLGTPVLSCQGDGTWDRPRPQCLLVS 2917
Score = 72.5 bits (170), Expect = 7e-12
Identities = 96/395 (24%), Positives = 166/395 (42%), Gaps = 45/395 (11%)
Query: 585 LTSCPEPEV-PSGGYM-EAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDG--EWSGDSPT 640
LT CP P + P+ + E ++ + + + C G L+G L C+ ++ G P
Sbjct: 2289 LTKCPPPTILPNAEVVTENEEFNIGDIVRYRCLPGFTLVGNEILTCKLGTYLQFEGPPPI 2348
Query: 641 CEYIDCGKLPTLPYGTMELLNGTTHLGSVIQY-SCTTNYRLVGPVRRTCTEEFQWSDSSP 699
CE + C L T +L+ ++ GS Q+ +C+ R+ + T E+ S+
Sbjct: 2349 CE-VHCPTNELLTDSTGVILS-QSYPGSYPQFQTCSWLVRVEPDYNISLTVEYFLSEK-- 2404
Query: 700 RCEEIRCSD-PIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYK 758
+ +E D P + +++GN + LI TS + V R + Y KG+K
Sbjct: 2405 QYDEFEIFDGPSGQSPLLKALSGN---YSAPLIVTSSSNSV--YLRWSSDHAYN-RKGFK 2458
Query: 759 VIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWE 818
+ ++S P C G I T P + +G A Y+ +
Sbjct: 2459 I------------RYS--APYCSLPRAPLHGFILGQTSTQPGGSIHFGCNAGYRLVGH-- 2502
Query: 819 LEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERG 878
+ R Q WS P+C+ ++C P A K G +V ++G +A Y C G
Sbjct: 2503 SMAICTRHPQGYHLWSEAIPLCQALSCGLPEAP-KNG---MVFGKEYTVGTKAVYSCSEG 2558
Query: 879 YNLK--GHQTRTCISKGQWN--GTVPVCIPIDCR--SPGNIENGK-IVISNGSTLFGSSV 931
Y+L+ T C+ G W+ P C+P+ C S ++E+G+ +I F + +
Sbjct: 2559 YHLQAGAEATAECLDTGLWSNRNVPPQCVPVTCPDVSSISVEHGRWRLIFETQYQFQAQL 2618
Query: 932 EYYCLSQYQRVGPFLRKCLDDGRWS-GEE-PSCEL 964
C Y G + +C +G+WS G+ P+C +
Sbjct: 2619 MLICDPGYYYTGQRVIRCQANGKWSLGDSTPTCRI 2653
Score = 55.6 bits (128), Expect = 9e-07
Identities = 37/124 (29%), Positives = 51/124 (41%), Gaps = 10/124 (8%)
Query: 857 GLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQ----WNGTVPVCIPIDCRSPGN 912
G ++ ++ GG H+ C GY L GH C Q W+ +P+C + C P
Sbjct: 2475 GFILGQTSTQPGGSIHFGCNAGYRLVGHSMAICTRHPQGYHLWSEAIPLCQALSCGLPEA 2534
Query: 913 IENGKIVISNGSTLFGSSVEYYCLSQY--QRVGPFLRKCLDDGRWSGEE--PSCELATNE 968
+NG +V T+ G+ Y C Y Q +CLD G WS P C T
Sbjct: 2535 PKNG-MVFGKEYTV-GTKAVYSCSEGYHLQAGAEATAECLDTGLWSNRNVPPQCVPVTCP 2592
Query: 969 AVDS 972
V S
Sbjct: 2593 DVSS 2596
Score = 54.0 bits (124), Expect = 3e-06
Identities = 30/89 (33%), Positives = 43/89 (48%), Gaps = 4/89 (4%)
Query: 571 NRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQ 630
NR G + + + EL CP+PE + G + Y V ++ F C G++L G P L CQ
Sbjct: 2105 NRPG-FKLEYQAYELQECPDPEPFANGIVRGAGYNVGQSVTFECLPGYQLTGHPVLTCQH 2163
Query: 631 --DGEWSGDSPTCEYIDCGKLPTLPYGTM 657
+ W P CE + CG T GT+
Sbjct: 2164 GTNRNWDHPLPKCE-VPCGGNITSSNGTV 2191
Score = 52.8 bits (121), Expect = 6e-06
Identities = 24/57 (42%), Positives = 30/57 (52%), Gaps = 2/57 (3%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
CG+P P NARV + +V + VYEC EGY G R C++ G WT P C
Sbjct: 3037 CGNPGTPSNARVVF--SDGLVFSSSIVYECREGYYATGLLSRHCSVNGTWTGSDPEC 3091
Score = 50.8 bits (116), Expect = 3e-05
Identities = 21/69 (30%), Positives = 37/69 (53%), Gaps = 2/69 (2%)
Query: 575 KWSYDIPSCELTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEW 634
K SY+ E SC +P +P+ G E ++ T+ F C+ +L+G+ + CQ++ +W
Sbjct: 550 KASYE--EIEQGSCGDPGIPAYGRREGSRFHHGDTLKFECQPAFELVGQKAITCQKNNQW 607
Query: 635 SGDSPTCEY 643
S P C +
Sbjct: 608 SAKKPGCVF 616
Score = 50.4 bits (115), Expect = 3e-05
Identities = 24/71 (33%), Positives = 40/71 (56%), Gaps = 3/71 (4%)
Query: 578 YDIPSCELTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLI-GEPNLVCQQDGEWSG 636
Y+ + + C +P +P G D+YV + + F C++G+ L GEP L C+ + +WS
Sbjct: 897 YETITLQSDHCLDPGIPVNGQRHGNDFYVGALVTFSCDSGYTLSDGEP-LECEPNFQWSR 955
Query: 637 DSPTCEYIDCG 647
P+CE + CG
Sbjct: 956 ALPSCEAL-CG 965
Score = 50.0 bits (114), Expect = 5e-05
Identities = 54/224 (24%), Positives = 87/224 (38%), Gaps = 16/224 (7%)
Query: 432 GARALYSCRENFTLVGNPERTC----GDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGH 487
GA + C + L G+PE C G W+ AP C+ C ++ G
Sbjct: 1794 GAIVRFECNSGYALQGSPEIECLPVPGALAQWNVSAPTCVVP-CGGNLTERRGTILSPGF 1852
Query: 488 KAGSLASYTCENGHILSGSTSVTCTLGGAWSGVP-PSCKYVNCGTPTIHK-GSFVLINGT 545
L S C ++ + + + S + + T+ GSF +GT
Sbjct: 1853 PEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQNWDSLEVFDGADNTVTMLGSF---SGT 1909
Query: 546 TTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFDYY 605
T ++ T Y L+ ++ + G + + + L+SCPEP VPS G Y
Sbjct: 1910 TV-PALLNSTSNQLY-LHFYSDISVSAAG-FHLEYKTVGLSSCPEPAVPSNGVKTGERYL 1966
Query: 606 VHSTINFHCEAGHKLIGEPNLVCQQD--GEWSGDSPTCEYIDCG 647
V+ ++F CE G+ L G ++ C W+ P C CG
Sbjct: 1967 VNDVVSFQCEPGYALQGHAHISCMPGTVRRWNYPPPLC-IAQCG 2009
Score = 49.6 bits (113), Expect = 6e-05
Identities = 26/67 (38%), Positives = 37/67 (55%), Gaps = 3/67 (4%)
Query: 740 GNTYRIGALVKYRCEKGYKVI-GESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTL 798
GN + +GALV + C+ GY + GE L CE N QWS P+C+ + CG + +G +
Sbjct: 920 GNDFYVGALVTFSCDSGYTLSDGEPLE-CEPNFQWSRALPSCEAL-CGGFIQGSSGTILS 977
Query: 799 PSNATFY 805
P FY
Sbjct: 978 PGFPDFY 984
Score = 49.2 bits (112), Expect = 8e-05
Identities = 60/241 (24%), Positives = 87/241 (36%), Gaps = 17/241 (7%)
Query: 740 GNTYRIGALVKYRCEKGYKVIGESLSTCE--DNGQWSGTTPTCQYVDCGNPGRIENGKVT 797
G Y +G V + C GY++ G + TC+ N W P C+ V CG NG V
Sbjct: 2134 GAGYNVGQSVTFECLPGYQLTGHPVLTCQHGTNRNWDHPLPKCE-VPCGGNITSSNGTVY 2192
Query: 798 LPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSG 857
P + Y ++ D W + I + N + P IT D Q G
Sbjct: 2193 SPGFPSPYSSSQ----DCVWLITVPIGHGVRLNLSLLQTEPSGDFITIWDGPQQTAPRLG 2248
Query: 858 LLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGK 917
+ T S+ + LK H R + G + C P + N +
Sbjct: 2249 VF----TRSMAKKTVQSSSNQVLLKFH--RDAATGGIFAIAFSAYPLTKCPPPTILPNAE 2302
Query: 918 IVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDG--RWSGEEPSCEL--ATNEAVDSG 973
+V N G V Y CL + VG + C ++ G P CE+ TNE +
Sbjct: 2303 VVTENEEFNIGDIVRYRCLPGFTLVGNEILTCKLGTYLQFEGPPPICEVHCPTNELLTDS 2362
Query: 974 T 974
T
Sbjct: 2363 T 2363
Score = 47.6 bits (108), Expect = 2e-04
Identities = 63/277 (22%), Positives = 106/277 (38%), Gaps = 35/277 (12%)
Query: 646 CGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTC----TEEFQWSDSSPRC 701
CG LP G + T +LG ++YSC + L G TC W P C
Sbjct: 179 CGNPGRLPNGIQQ--GSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPSC 236
Query: 702 E-EIRCSDPIVAEKSIVSVTG-NDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKV 759
+ C + + I+S H + + ++G+T + + ++ E GY
Sbjct: 237 RADDACGGTLRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIAL-VFIDFQLEDGYDF 295
Query: 760 IGESLSTCEDNGQW-SGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWE 818
+ ++ E + W +G + + N R+ T N G +A YQ + E
Sbjct: 296 L--EVTGTEGSSLWFTGASLPAPVISSKNWLRLH---FTSDGNHRQRGFSAQYQVKKQIE 350
Query: 819 LE--GVIRRMCQENGTWSLEPPICKEI-------TCPDPSAQIKAGSGLLVVTSTLSIGG 869
L+ GV ++N S + + ++ CPDP + G L S +G
Sbjct: 351 LKSRGVKLMPSKDN---SQKTSVLTQVGVSQGHNMCPDPGIP-ERGKRL---GSDFRLGS 403
Query: 870 EAHYQCERGYNLKGHQTRTCISKGQ----WNGTVPVC 902
+ C GY+L+G + TC+ W+ PVC
Sbjct: 404 SVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVC 440
Score = 45.6 bits (103), Expect = 0.001
Identities = 23/67 (34%), Positives = 32/67 (47%), Gaps = 2/67 (2%)
Query: 349 LPPTCGSPDKLLNTTILGNDY-DVGSRIVYKCPEGHMLLG-DKSRHCKKDGFWSGAPPSC 406
+P C P+ + + D +G ++Y C EG L G + R CK DG W+G PP C
Sbjct: 3330 VPHHCRQPETPTHANVGALDLPSMGYTLIYSCQEGFSLKGGSEHRTCKADGSWTGKPPIC 3389
Query: 407 KYVNCGG 413
V G
Sbjct: 3390 LEVRPNG 3396
Score = 44.8 bits (101), Expect = 0.002
Identities = 24/76 (31%), Positives = 34/76 (44%), Gaps = 3/76 (3%)
Query: 584 ELTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGE--WSGDSPTC 641
+L C EPEVP+ + + V T+ F C G++L G + C WS P C
Sbjct: 1075 DLEPCEEPEVPAYSIRKGLQFGVGDTLTFSCFPGYRLEGTARITCLGGRRRLWSSPLPRC 1134
Query: 642 EYIDCGKLPTLPYGTM 657
+CG T GT+
Sbjct: 1135 -VAECGNSVTGTQGTL 1149
Score = 44.4 bits (100), Expect = 0.002
Identities = 27/90 (30%), Positives = 41/90 (45%), Gaps = 3/90 (3%)
Query: 333 NDVGCNLDYLHWICQYLPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRH 392
+D+G L Y Q C P +N GND+ VG+ + + C G+ L +
Sbjct: 889 SDIGFQLRYETITLQ--SDHCLDPGIPVNGQRHGNDFYVGALVTFSCDSGYTLSDGEPLE 946
Query: 393 CKKDGFWSGAPPSCKYVNCGGLTPIEDGDV 422
C+ + WS A PSC+ + CGG G +
Sbjct: 947 CEPNFQWSRALPSCEAL-CGGFIQGSSGTI 975
Score = 44.0 bits (99), Expect = 0.003
Identities = 20/70 (28%), Positives = 34/70 (48%), Gaps = 1/70 (1%)
Query: 737 RDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKV 796
R G+ + G +K+ C+ ++++G+ TC+ N QWS P C + C +G V
Sbjct: 571 RREGSRFHHGDTLKFECQPAFELVGQKAITCQKNNQWSAKKPGCVF-SCFFNFTSPSGVV 629
Query: 797 TLPSNATFYG 806
P+ YG
Sbjct: 630 LSPNYPEDYG 639
Score = 43.6 bits (98), Expect = 0.004
Identities = 23/62 (37%), Positives = 31/62 (50%), Gaps = 4/62 (6%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC-GT 60
CGHP PP++++S ++ G + Y C L G R C L G WT P C GT
Sbjct: 2918 CGHPGSPPHSQMS---GDSYTVGAVVRYSCIGKRTLVGNSTRMCGLDGHWTGSLPHCSGT 2974
Query: 61 NV 62
+V
Sbjct: 2975 SV 2976
Score = 42.3 bits (95), Expect = 0.009
Identities = 24/70 (34%), Positives = 35/70 (50%), Gaps = 6/70 (8%)
Query: 582 SCELTSCPEPEVPSGGY-MEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGE---WSGD 637
S EL C +P P GY + ++ S+++F C+ G+ L G L+C GE W
Sbjct: 1245 SFELIKCEDPGTPKFGYKVHDEGHFAGSSVSFSCDPGYSLRGSEELLC-LSGERRTWDRP 1303
Query: 638 SPTCEYIDCG 647
PTC +CG
Sbjct: 1304 LPTC-VAECG 1312
Score = 41.9 bits (94), Expect = 0.012
Identities = 20/52 (38%), Positives = 28/52 (53%), Gaps = 5/52 (9%)
Query: 2 CGHPAVPPNA-RVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWT 52
CG +PPN R+ + V G A++ C+ GY L G+R REC G W+
Sbjct: 2656 CGELPIPPNGHRIGTLS----VYGATAIFSCNSGYTLVGSRVRECMANGLWS 2703
Score = 41.5 bits (93), Expect = 0.016
Identities = 18/58 (31%), Positives = 29/58 (50%), Gaps = 3/58 (5%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCG 59
CG P +P + I ++ GT+ + C+ G+ L G+ +R C G W+ P CG
Sbjct: 2979 CGDPGIPAHG---IRLGDSFDPGTVMRFSCEAGHVLRGSSERTCQANGSWSGSQPECG 3033
Score = 41.5 bits (93), Expect = 0.016
Identities = 20/58 (34%), Positives = 28/58 (48%), Gaps = 3/58 (5%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQ-RECTLRGDWTLEPPFC 58
C P P +A V + ++ G +Y C EG+ L G + R C G WT +PP C
Sbjct: 3334 CRQPETPTHANVGALDLPSM--GYTLIYSCQEGFSLKGGSEHRTCKADGSWTGKPPIC 3389
Score = 40.7 bits (91), Expect = 0.028
Identities = 27/99 (27%), Positives = 44/99 (44%), Gaps = 6/99 (6%)
Query: 331 LWNDVGCNLDYLHWICQYLPP-TCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDK 389
L +D + H + LP TCG+P +L N G+ +++G ++ Y C G L G
Sbjct: 156 LISDYAVSAQGFHATYEVLPSHTCGNPGRLPNGIQQGSTFNLGDKVRYSCNLGFFLEGHA 215
Query: 390 SRHC----KKDGFWSGAPPSCKYVN-CGGLTPIEDGDVA 423
C + W PSC+ + CGG + G ++
Sbjct: 216 VLTCHAGSENSATWDFPLPSCRADDACGGTLRGQSGIIS 254
Score = 40.7 bits (91), Expect = 0.028
Identities = 18/63 (28%), Positives = 28/63 (44%), Gaps = 4/63 (6%)
Query: 588 CPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGE----WSGDSPTCEY 643
CP+P +P G D+ + S++ F C G+ L G + C + + WS P C
Sbjct: 383 CPDPGIPERGKRLGSDFRLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRA 442
Query: 644 IDC 646
C
Sbjct: 443 RMC 445
Score = 40.7 bits (91), Expect = 0.028
Identities = 20/62 (32%), Positives = 30/62 (48%), Gaps = 1/62 (1%)
Query: 469 DWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVN 528
D C DP N N G+L +++C++G+ LS + C WS PSC+ +
Sbjct: 905 DHCLDPGIPVNGQRHGNDFYVGALVTFSCDSGYTLSDGEPLECEPNFQWSRALPSCEAL- 963
Query: 529 CG 530
CG
Sbjct: 964 CG 965
Score = 40.7 bits (91), Expect = 0.028
Identities = 23/82 (28%), Positives = 35/82 (42%), Gaps = 5/82 (6%)
Query: 580 IPSCELTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQD----GEWS 635
+P T C P G D+ V + + F C +G+ L G P + C +W+
Sbjct: 1767 VPRTSATQCSSVPEPRYGKRLGSDFSVGAIVRFECNSGYALQGSPEIECLPVPGALAQWN 1826
Query: 636 GDSPTCEYIDCGKLPTLPYGTM 657
+PTC + CG T GT+
Sbjct: 1827 VSAPTC-VVPCGGNLTERRGTI 1847
Score = 39.5 bits (88), Expect = 0.064
Identities = 20/63 (31%), Positives = 27/63 (42%), Gaps = 4/63 (6%)
Query: 471 CPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTC----TLGGAWSGVPPSCKY 526
CPDP + + GS +TC G+ L GS +TC + AWS P C+
Sbjct: 383 CPDPGIPERGKRLGSDFRLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRA 442
Query: 527 VNC 529
C
Sbjct: 443 RMC 445
Score = 39.5 bits (88), Expect = 0.064
Identities = 27/104 (25%), Positives = 45/104 (43%), Gaps = 10/104 (9%)
Query: 523 SCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVC--NRDGKWSYDI 580
S + + C P K + + + GS F+C+P Y L G+EEL+C W +
Sbjct: 1245 SFELIKCEDPGTPKFGYKVHDEGHFAGSSVSFSCDPGYSLRGSEELLCLSGERRTWDRPL 1304
Query: 581 PSCELTSC-------PEPEVPSGGYMEAFDYYVHSTINFHCEAG 617
P+C + C +V S GY +++ ++ EAG
Sbjct: 1305 PTC-VAECGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAG 1347
Score = 39.5 bits (88), Expect = 0.064
Identities = 31/126 (24%), Positives = 50/126 (39%), Gaps = 9/126 (7%)
Query: 292 RTWQW-VDGELVSKPSWGKDQPNNYNGEQNCVVLDGGRGWLWNDVGCNLDYLHWICQYLP 350
R W V+ ++ K G P + + N VVL + + G + +
Sbjct: 1367 RIWDGPVESGVLLKELSGPALPKDLHSTFNSVVLQFSTDFFTSKQGFAIQF----SVSTA 1422
Query: 351 PTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKK---DGFWSGAPPSCK 407
+C P N + G+ ++ G V++C G+ L G C K FW +PP+C
Sbjct: 1423 TSCNDPGIPQNGSRSGDSWEAGDSTVFQCDPGYALQGSAEISCVKIENRFFWQPSPPTC- 1481
Query: 408 YVNCGG 413
CGG
Sbjct: 1482 IAPCGG 1487
Score = 39.5 bits (88), Expect = 0.064
Identities = 21/72 (29%), Positives = 32/72 (44%), Gaps = 3/72 (4%)
Query: 353 CGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCK--KDGFWSGAPPSCKYVN 410
C P+ N + G Y+VG + ++C G+ L G C+ + W P C+ V
Sbjct: 2121 CPDPEPFANGIVRGAGYNVGQSVTFECLPGYQLTGHPVLTCQHGTNRNWDHPLPKCE-VP 2179
Query: 411 CGGLTPIEDGDV 422
CGG +G V
Sbjct: 2180 CGGNITSSNGTV 2191
Score = 39.1 bits (87), Expect = 0.085
Identities = 24/63 (38%), Positives = 31/63 (49%), Gaps = 8/63 (12%)
Query: 844 TCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCI----SKGQWNGTV 899
+C DP + IK G+ V S L +G Y C GY ++G T +CI K WN
Sbjct: 1597 SCFDPGS-IKNGTR---VGSDLKLGSSVTYYCHGGYEVEGTSTLSCILGPDGKPVWNNPR 1652
Query: 900 PVC 902
PVC
Sbjct: 1653 PVC 1655
Score = 39.1 bits (87), Expect = 0.085
Identities = 21/62 (33%), Positives = 29/62 (46%), Gaps = 3/62 (4%)
Query: 471 CPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLG--GAWSGVPPSCKYVN 528
CPDP +N V G+ G ++ C G+ L+G +TC G W P C+ V
Sbjct: 2121 CPDPEPFANGIVRGAGYNVGQSVTFECLPGYQLTGHPVLTCQHGTNRNWDHPLPKCE-VP 2179
Query: 529 CG 530
CG
Sbjct: 2180 CG 2181
Score = 39.1 bits (87), Expect = 0.085
Identities = 22/74 (29%), Positives = 35/74 (47%), Gaps = 4/74 (5%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTN 61
CGHP P N ++ N+ N+ + + C+ GY GA + +C G W+ P C
Sbjct: 2797 CGHPGNPVNG-LTQGNQFNL--NDVVKFVCNPGYMAEGAARSQCLASGQWSDMLPTCRI- 2852
Query: 62 VAFRKPANQSTTVR 75
+ P +Q +VR
Sbjct: 2853 INCTDPGHQENSVR 2866
Score = 38.7 bits (86), Expect = 0.11
Identities = 56/246 (22%), Positives = 85/246 (34%), Gaps = 24/246 (9%)
Query: 352 TCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHC--KKDG--FWSGAPPSCK 407
+C P + N T +G+D +GS + Y C G+ + G + C DG W+ P C
Sbjct: 1597 SCFDPGSIKNGTRVGSDLKLGSSVTYYCHGGYEVEGTSTLSCILGPDGKPVWNNPRPVCT 1656
Query: 408 YVNCGGLTPIEDGDVALIDN---RTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAP 464
CGG DG V L N T G LY F V G + A
Sbjct: 1657 -APCGGQYVGSDG-VVLSPNYPQNYTSGQICLY-----FVTVPKDYVVFGQFAFFH-TAL 1708
Query: 465 RCLFDWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGG---AWSGVP 521
+ + S +++G G N ++ S G + VP
Sbjct: 1709 NDVVEVHDGHSQHSRLLSSLSGSHTGESLPLATSNQVLIKFSAKGLAPARGFHFVYQAVP 1768
Query: 522 PSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVC----NRDGKWS 577
+ P G + + G+I +F C Y L G+ E+ C +W+
Sbjct: 1769 RTSATQCSSVPEPRYGK--RLGSDFSVGAIVRFECNSGYALQGSPEIECLPVPGALAQWN 1826
Query: 578 YDIPSC 583
P+C
Sbjct: 1827 VSAPTC 1832
Score = 38.7 bits (86), Expect = 0.11
Identities = 25/61 (40%), Positives = 31/61 (50%), Gaps = 8/61 (13%)
Query: 907 CRSPGNIENGKIVISNGSTL-FGSSVEYYCLSQYQRVGPFLRKCL--DDGR--WSGEEPS 961
C PG+I+NG V GS L GSSV YYC Y+ G C+ DG+ W+ P
Sbjct: 1598 CFDPGSIKNGTRV---GSDLKLGSSVTYYCHGGYEVEGTSTLSCILGPDGKPVWNNPRPV 1654
Query: 962 C 962
C
Sbjct: 1655 C 1655
Score = 38.7 bits (86), Expect = 0.11
Identities = 25/83 (30%), Positives = 33/83 (39%), Gaps = 4/83 (4%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTN 61
CG P N + N EN VY+C+ G+ L G R C W+ + PFC
Sbjct: 2739 CGTPEPIVNGHI---NGENYSYRGSVVYQCNAGFRLIGMSVRICQQDHHWSGKTPFC-VP 2794
Query: 62 VAFRKPANQSTTVRGGAAANGND 84
+ P N + G N ND
Sbjct: 2795 ITCGHPGNPVNGLTQGNQFNLND 2817
Score = 38.3 bits (85), Expect = 0.15
Identities = 27/81 (33%), Positives = 36/81 (44%), Gaps = 7/81 (8%)
Query: 626 LVCQQDGEWS--GDSPTCEYIDCGKL--PTLP-YGTMELLNGTTHLGSVIQYSCTTNYRL 680
L+ Q DG S G + E I+ G P +P YG E H G +++ C + L
Sbjct: 536 LLFQTDGSGSSLGFKASYEEIEQGSCGDPGIPAYGRRE--GSRFHHGDTLKFECQPAFEL 593
Query: 681 VGPVRRTCTEEFQWSDSSPRC 701
VG TC + QWS P C
Sbjct: 594 VGQKAITCQKNNQWSAKKPGC 614
Score = 38.3 bits (85), Expect = 0.15
Identities = 62/247 (25%), Positives = 96/247 (38%), Gaps = 43/247 (17%)
Query: 665 HLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDR 724
++G+++ +SC + Y L C FQWS + P CE + C I + G
Sbjct: 924 YVGALVTFSCDSGYTLSDGEPLECEPNFQWSRALPSCEAL-CGGFIQGSSGTILSPGFPD 982
Query: 725 SHGHTL-----IRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPT 779
+ + L I TS + V T+ + E G+ + L T +NG S T P
Sbjct: 983 FYPNNLNCTWIIETSHGKGVFFTFH-----TFHLESGHDYL---LIT--ENG--SFTQPL 1030
Query: 780 CQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPI 839
Q P I G L N T A + D + EG + + LEP
Sbjct: 1031 RQLTGSRLPAPISAG---LYGNFT---AQVRFISDFSMSYEGFNITFSE----YDLEP-- 1078
Query: 840 CKEITCPD-PSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCIS--KGQWN 896
C+E P+ P+ I+ G +G + C GY L+G TC+ + W+
Sbjct: 1079 CEE---PEVPAYSIRKG-------LQFGVGDTLTFSCFPGYRLEGTARITCLGGRRRLWS 1128
Query: 897 GTVPVCI 903
+P C+
Sbjct: 1129 SPLPRCV 1135
Score = 37.5 bits (83), Expect = 0.26
Identities = 14/36 (38%), Positives = 22/36 (61%)
Query: 549 GSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCE 584
G++ F+C+ Y L+ E L C + +WS +PSCE
Sbjct: 926 GALVTFSCDSGYTLSDGEPLECEPNFQWSRALPSCE 961
Score = 37.1 bits (82), Expect = 0.34
Identities = 22/63 (34%), Positives = 28/63 (44%), Gaps = 4/63 (6%)
Query: 471 CPDPPAVS-NASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLG--GAWSGVPPSCKYV 527
C DP V GH AGS S++C+ G+ L GS + C G W P+C
Sbjct: 1251 CEDPGTPKFGYKVHDEGHFAGSSVSFSCDPGYSLRGSEELLCLSGERRTWDRPLPTC-VA 1309
Query: 528 NCG 530
CG
Sbjct: 1310 ECG 1312
Score = 37.1 bits (82), Expect = 0.34
Identities = 20/65 (30%), Positives = 31/65 (47%), Gaps = 5/65 (7%)
Query: 739 VGNTYRIGALVKYRCEKGYKVIG----ESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENG 794
+G+ + +GA+V++ C GY + G E L QW+ + PTC V CG G
Sbjct: 1787 LGSDFSVGAIVRFECNSGYALQGSPEIECLPVPGALAQWNVSAPTC-VVPCGGNLTERRG 1845
Query: 795 KVTLP 799
+ P
Sbjct: 1846 TILSP 1850
Score = 36.7 bits (81), Expect = 0.45
Identities = 19/66 (28%), Positives = 33/66 (50%), Gaps = 4/66 (6%)
Query: 739 VGNTYRIGALVKYRCEKGYKVIGESLSTC----EDNGQWSGTTPTCQYVDCGNPGRIENG 794
+G+ +R+G+ V++ C +GY + G TC + WS P C+ C R +G
Sbjct: 395 LGSDFRLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRGPSG 454
Query: 795 KVTLPS 800
+T P+
Sbjct: 455 IITSPN 460
Score = 36.3 bits (80), Expect = 0.60
Identities = 21/60 (35%), Positives = 27/60 (45%), Gaps = 6/60 (10%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTL---RGDWTLEPPFC 58
C P +P N S + E AG V++CD GY L G+ + C R W PP C
Sbjct: 1425 CNDPGIPQNGSRSGDSWE---AGDSTVFQCDPGYALQGSAEISCVKIENRFFWQPSPPTC 1481
Score = 35.9 bits (79), Expect = 0.79
Identities = 20/51 (39%), Positives = 27/51 (52%), Gaps = 4/51 (7%)
Query: 365 LGNDYDVGSRIVYKCPEGHMLLGDKSRHCKK--DGF--WSGAPPSCKYVNC 411
LG+D+ +GS + + C EG+ L G K C K D F WS P C+ C
Sbjct: 395 LGSDFRLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRARMC 445
Score = 35.9 bits (79), Expect = 0.79
Identities = 17/65 (26%), Positives = 31/65 (47%), Gaps = 5/65 (7%)
Query: 548 YGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELT-----SCPEPEVPSGGYMEAF 602
+G +F C+P + L G + + C ++ +WS P C + + P V S Y E +
Sbjct: 579 HGDTLKFECQPAFELVGQKAITCQKNNQWSAKKPGCVFSCFFNFTSPSGVVLSPNYPEDY 638
Query: 603 DYYVH 607
++H
Sbjct: 639 GNHLH 643
Score = 35.9 bits (79), Expect = 0.79
Identities = 21/75 (28%), Positives = 30/75 (40%), Gaps = 4/75 (5%)
Query: 586 TSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVC---QQDGEWSGDSPTCE 642
TSC +P +P G + + F C+ G+ L G + C + W PTC
Sbjct: 1423 TSCNDPGIPQNGSRSGDSWEAGDSTVFQCDPGYALQGSAEISCVKIENRFFWQPSPPTC- 1481
Query: 643 YIDCGKLPTLPYGTM 657
CG T P G +
Sbjct: 1482 IAPCGGDLTGPSGVI 1496
Score = 35.9 bits (79), Expect = 0.79
Identities = 19/63 (30%), Positives = 28/63 (44%), Gaps = 4/63 (6%)
Query: 471 CPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTL---GGAWSGVPPSCKYV 527
C DP N S + + +AG + C+ G+ L GS ++C W PP+C
Sbjct: 1425 CNDPGIPQNGSRSGDSWEAGDSTVFQCDPGYALQGSAEISCVKIENRFFWQPSPPTC-IA 1483
Query: 528 NCG 530
CG
Sbjct: 1484 PCG 1486
Score = 35.9 bits (79), Expect = 0.79
Identities = 27/77 (35%), Positives = 32/77 (41%), Gaps = 5/77 (6%)
Query: 1 RCGHPAVPPNARVSIPNEE-NIVAGTIAVYECDEGYELFGARQRECTLRGDWTLE--PPF 57
+C P + PNA V NEE NI G I Y C G+ L G C L E PP
Sbjct: 2291 KCPPPTILPNAEVVTENEEFNI--GDIVRYRCLPGFTLVGNEILTCKLGTYLQFEGPPPI 2348
Query: 58 CGTNVAFRKPANQSTTV 74
C + + ST V
Sbjct: 2349 CEVHCPTNELLTDSTGV 2365
Score = 35.5 bits (78), Expect = 1.0
Identities = 25/61 (40%), Positives = 27/61 (44%), Gaps = 7/61 (11%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYEL-FGAR-QRECTLRGDWTLE--PPF 57
CG P P N V + GT AVY C EGY L GA EC G W+ PP
Sbjct: 2529 CGLPEAPKNGMVF---GKEYTVGTKAVYSCSEGYHLQAGAEATAECLDTGLWSNRNVPPQ 2585
Query: 58 C 58
C
Sbjct: 2586 C 2586
Score = 35.1 bits (77), Expect = 1.4
Identities = 20/63 (31%), Positives = 28/63 (44%), Gaps = 4/63 (6%)
Query: 660 LNGTTHLGSVIQYSCTTNYRLVGPVRRTC---TEEF-QWSDSSPRCEEIRCSDPIVAEKS 715
L LGS +Q++C Y L G R TC ++ F WSD P C C +
Sbjct: 395 LGSDFRLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRGPSG 454
Query: 716 IVS 718
I++
Sbjct: 455 IIT 457
Score = 35.1 bits (77), Expect = 1.4
Identities = 18/56 (32%), Positives = 27/56 (48%), Gaps = 2/56 (3%)
Query: 785 CGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPIC 840
CG+PG G+ + +G T ++C +EL G CQ+N WS + P C
Sbjct: 561 CGDPGIPAYGR--REGSRFHHGDTLKFECQPAFELVGQKAITCQKNNQWSAKKPGC 614
Score = 35.1 bits (77), Expect = 1.4
Identities = 17/57 (29%), Positives = 25/57 (43%), Gaps = 2/57 (3%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C P VP + N + G+ ++ C +GY L G+ R C W+ PP C
Sbjct: 3275 CADPGVPQFGIQN--NSQGYQVGSTVLFRCQKGYLLQGSTTRTCLPNLTWSGTPPDC 3329
Score = 34.7 bits (76), Expect = 1.8
Identities = 15/57 (26%), Positives = 26/57 (45%)
Query: 352 TCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKY 408
+CG P G+ + G + ++C L+G K+ C+K+ WS P C +
Sbjct: 560 SCGDPGIPAYGRREGSRFHHGDTLKFECQPAFELVGQKAITCQKNNQWSAKKPGCVF 616
Score = 34.7 bits (76), Expect = 1.8
Identities = 23/89 (25%), Positives = 36/89 (40%), Gaps = 5/89 (5%)
Query: 716 IVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTC----EDNG 771
++ T N R + VG+ ++G+ V Y C GY+V G S +C +
Sbjct: 1587 VIDYTENPRESCFDPGSIKNGTRVGSDLKLGSSVTYYCHGGYEVEGTSTLSCILGPDGKP 1646
Query: 772 QWSGTTPTCQYVDCGNPGRIENGKVTLPS 800
W+ P C CG +G V P+
Sbjct: 1647 VWNNPRPVCT-APCGGQYVGSDGVVLSPN 1674
Score = 34.7 bits (76), Expect = 1.8
Identities = 19/60 (31%), Positives = 26/60 (43%), Gaps = 7/60 (11%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQREC---TLRGDWTLEPPFC 58
C PAVP N + E + + ++C+ GY L G C T+R W PP C
Sbjct: 1949 CPEPAVPSNG---VKTGERYLVNDVVSFQCEPGYALQGHAHISCMPGTVR-RWNYPPPLC 2004
Score = 34.3 bits (75), Expect = 2.4
Identities = 23/79 (29%), Positives = 37/79 (46%), Gaps = 9/79 (11%)
Query: 343 HWICQYLPPT----CGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKD-- 396
H++ Q +P T C S + LG+D+ VG+ + ++C G+ L G C
Sbjct: 1761 HFVYQAVPRTSATQCSSVPEPRYGKRLGSDFSVGAIVRFECNSGYALQGSPEIECLPVPG 1820
Query: 397 --GFWSGAPPSCKYVNCGG 413
W+ + P+C V CGG
Sbjct: 1821 ALAQWNVSAPTC-VVPCGG 1838
Score = 34.3 bits (75), Expect = 2.4
Identities = 21/65 (32%), Positives = 32/65 (49%), Gaps = 12/65 (18%)
Query: 844 TCPDPSAQ---IKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCI--SKGQWNGT 898
+CP+P+ +K G LV +QCE GY L+GH +C+ + +WN
Sbjct: 1948 SCPEPAVPSNGVKTGERYLV-------NDVVSFQCEPGYALQGHAHISCMPGTVRRWNYP 2000
Query: 899 VPVCI 903
P+CI
Sbjct: 2001 PPLCI 2005
Score = 33.9 bits (74), Expect = 3.2
Identities = 14/42 (33%), Positives = 19/42 (45%)
Query: 427 NRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLF 468
+R HG + C+ F LVG TC W + P C+F
Sbjct: 575 SRFHHGDTLKFECQPAFELVGQKAITCQKNNQWSAKKPGCVF 616
Score = 33.9 bits (74), Expect = 3.2
Identities = 20/66 (30%), Positives = 32/66 (48%), Gaps = 8/66 (12%)
Query: 863 STLSIGGEAHYQCERGYNLKGHQTRTCI----SKGQWNGTVPVCIPIDCRSPGNI-ENGK 917
S S+G ++C GY L+G C+ + QWN + P C+ + C GN+ E
Sbjct: 1789 SDFSVGAIVRFECNSGYALQGSPEIECLPVPGALAQWNVSAPTCV-VPC--GGNLTERRG 1845
Query: 918 IVISNG 923
++S G
Sbjct: 1846 TILSPG 1851
Score = 33.5 bits (73), Expect = 4.2
Identities = 15/47 (31%), Positives = 25/47 (53%), Gaps = 1/47 (2%)
Query: 863 STLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRS 909
ST ++G + Y C G+ L+GH TC + + + T +P CR+
Sbjct: 193 STFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLP-SCRA 238
Score = 33.5 bits (73), Expect = 4.2
Identities = 22/88 (25%), Positives = 35/88 (39%), Gaps = 7/88 (7%)
Query: 845 CPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCI--SKGQWNGTVPVC 902
CPDP +V + ++G ++C GY L GH TC + W+ +P C
Sbjct: 2121 CPDPEPFANG----IVRGAGYNVGQSVTFECLPGYQLTGHPVLTCQHGTNRNWDHPLPKC 2176
Query: 903 IPIDCRSPGNIENGKIVISNGSTLFGSS 930
+ C NG + + + SS
Sbjct: 2177 -EVPCGGNITSSNGTVYSPGFPSPYSSS 2203
Score = 33.1 bits (72), Expect = 5.6
Identities = 19/70 (27%), Positives = 28/70 (40%), Gaps = 4/70 (5%)
Query: 549 GSIAQFTCEPDYWLNGAEELVC----NRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFDY 604
GS QFTC Y L G++ + C + WS P C C G + + ++
Sbjct: 402 GSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRGPSGIITSPNF 461
Query: 605 YVHSTINFHC 614
+ N HC
Sbjct: 462 PIQYDNNAHC 471
Score = 32.7 bits (71), Expect = 7.4
Identities = 15/57 (26%), Positives = 22/57 (38%), Gaps = 3/57 (5%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C P +P N + + + G + + CD GY L EC W+ P C
Sbjct: 907 CLDPGIPVNGQ---RHGNDFYVGALVTFSCDSGYTLSDGEPLECEPNFQWSRALPSC 960
Score = 32.7 bits (71), Expect = 7.4
Identities = 19/57 (33%), Positives = 25/57 (43%), Gaps = 3/57 (5%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C P + PN +V + + G+ Y C EGY+L C G WT E P C
Sbjct: 3156 CKPPPLIPNGKVV---GSDFMWGSSVTYACLEGYQLSLPAVFTCEGNGSWTGELPQC 3209
Score = 32.3 bits (70), Expect = 9.7
Identities = 20/67 (29%), Positives = 28/67 (41%), Gaps = 2/67 (2%)
Query: 777 TPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLE 836
T T Q C +PG NG+ N + GA + CD + L C+ N WS
Sbjct: 899 TITLQSDHCLDPGIPVNGQ--RHGNDFYVGALVTFSCDSGYTLSDGEPLECEPNFQWSRA 956
Query: 837 PPICKEI 843
P C+ +
Sbjct: 957 LPSCEAL 963
Score = 32.3 bits (70), Expect = 9.7
Identities = 11/38 (28%), Positives = 21/38 (55%), Gaps = 2/38 (5%)
Query: 868 GGEAHYQCERGYNLKGHQTRTCIS--KGQWNGTVPVCI 903
G + C+ GY+L+G + C+S + W+ +P C+
Sbjct: 1271 GSSVSFSCDPGYSLRGSEELLCLSGERRTWDRPLPTCV 1308
>AB067471-1|BAB67777.1| 946|Homo sapiens KIAA1884 protein protein.
Length = 946
Score = 293 bits (720), Expect = 2e-78
Identities = 168/562 (29%), Positives = 255/562 (45%), Gaps = 38/562 (6%)
Query: 353 CGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCG 412
CG+P+ ++N I G +Y +VY+C G L+G R C++D WSG P C V+CG
Sbjct: 175 CGTPEPIVNGHINGENYSYRGSVVYQCNAGFRLIGMSVRICQQDHHWSGKTPFCVLVSCG 234
Query: 413 GLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL---FD 469
P + + T GA YSC TLVGN R CG +G W G P C
Sbjct: 235 H--PGSPPHSQMSGDSYTVGAVVRYSCIGKRTLVGNSTRMCGLDGHWTGSLPHCSGTSVG 292
Query: 470 WCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNC 529
C DP ++ + G++ ++CE GH+L GS+ TC G+WSG P C ++C
Sbjct: 293 VCGDPGIPAHGIRLGDSFDPGTVMRFSCEAGHVLRGSSERTCQANGSWSGSQPECGVISC 352
Query: 530 GTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCP 589
G P + V+ + + S + C Y+ G C+ +G W+ P C + +C
Sbjct: 353 GNPGTPSNARVVFSDGLVFSSSIVYECREGYYATGLLSRHCSVNGTWTGSDPECLVINCG 412
Query: 590 EPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGE--PNLVCQQDGEWSGDSPTCEYIDCG 647
+P +P+ G D+ + T+ + C G+ + L C +D W+G P C+ + C
Sbjct: 413 DPGIPANGLRLGNDFRYNKTVTYQCVPGYMMESHRVSVLSCTKDRTWNGTKPVCKALMCK 472
Query: 648 KLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCS 707
P +P G +++ GS + Y+C Y+L P TC W+ P+C + C
Sbjct: 473 PPPLIPNG--KVVGSDFMWGSSVTYACLEGYQLSLPAVFTCEGNGSWTGELPQCFPVFCG 530
Query: 708 DPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTC 767
DP V S G D G +YR + V + C ++G C
Sbjct: 531 DPGVP------------SRGR-------REDRGFSYR--SSVSFSCHPPLVLVGSPRRFC 569
Query: 768 EDNGQWSGTTPTC---QYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIR 824
+ +G WSGT P+C C +PG + G + S G+T ++C + + L+G
Sbjct: 570 QSDGTWSGTQPSCIDPTLTTCADPGVPQFG-IQNNSQGYQVGSTVLFRCQKGYLLQGSTT 628
Query: 825 RMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLK-G 883
R C N TWS PP C C P A G L + S+G Y C+ G++LK G
Sbjct: 629 RTCLPNLTWSGTPPDCVPHHCRQPETPTHANVGALDLP---SMGYTLIYSCQEGFSLKGG 685
Query: 884 HQTRTCISKGQWNGTVPVCIPI 905
+ RTC + G W G P+C+ +
Sbjct: 686 SEHRTCKADGSWTGKPPICLEV 707
Score = 287 bits (704), Expect = 1e-76
Identities = 170/546 (31%), Positives = 255/546 (46%), Gaps = 41/546 (7%)
Query: 430 THGARALYSCRENFTLVGNPERT--CGDEGIWDGE--APRCLFDWCPDPPAVSNAS---- 481
T G +A+YSC E + L E T C D G+W P+C+ CPD ++S
Sbjct: 7 TVGTKAMYSCSEGYHLQAGAEATAECLDTGLWSNRNVPPQCVPVTCPDVSSISVEHGRWR 66
Query: 482 -VTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWS--GVPPSCKYVNCGTPTIHKGS 538
+ ++ + C+ G+ +G + C G WS P+C+ ++CG I
Sbjct: 67 LIFETQYQFQAQLMLICDPGYYYTGQRVIRCQANGKWSLGDSTPTCRIISCGELPIPPNG 126
Query: 539 FVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGY 598
I + YG+ A F+C Y L G+ C +G WS C C PE G+
Sbjct: 127 H-RIGTLSVYGATAIFSCNSGYTLVGSRVRECMANGLWSGSEVRCLAGHCGTPEPIVNGH 185
Query: 599 MEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTME 658
+ +Y ++ + C AG +LIG +CQQD WSG +P C + CG + P+ M
Sbjct: 186 INGENYSYRGSVVYQCNAGFRLIGMSVRICQQDHHWSGKTPFCVLVSCGHPGSPPHSQMS 245
Query: 659 LLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVS 718
+ +G+V++YSC LVG R C + W+ S P C + V
Sbjct: 246 --GDSYTVGAVVRYSCIGKRTLVGNSTRMCGLDGHWTGSLPHC-----------SGTSVG 292
Query: 719 VTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTP 778
V G+ H + +G+++ G ++++ CE G+ + G S TC+ NG WSG+ P
Sbjct: 293 VCGDPGIPAHGI-------RLGDSFDPGTVMRFSCEAGHVLRGSSERTCQANGSWSGSQP 345
Query: 779 TCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPP 838
C + CGNPG N +V S+ + ++ Y+C E + G++ R C NGTW+ P
Sbjct: 346 ECGVISCGNPGTPSNARVVF-SDGLVFSSSIVYECREGYYATGLLSRHCSVNGTWTGSDP 404
Query: 839 ICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTR--TCISKGQWN 896
C I C DP I A L + + YQC GY ++ H+ +C WN
Sbjct: 405 ECLVINCGDPG--IPANG--LRLGNDFRYNKTVTYQCVPGYMMESHRVSVLSCTKDRTWN 460
Query: 897 GTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWS 956
GT PVC + C+ P I NGK+V S+ ++GSSV Y CL YQ P + C +G W+
Sbjct: 461 GTKPVCKALMCKPPPLIPNGKVVGSD--FMWGSSVTYACLEGYQLSLPAVFTCEGNGSWT 518
Query: 957 GEEPSC 962
GE P C
Sbjct: 519 GELPQC 524
Score = 287 bits (704), Expect = 1e-76
Identities = 170/601 (28%), Positives = 274/601 (45%), Gaps = 42/601 (6%)
Query: 372 GSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRTTH 431
G+ ++ C G+ L+G + R C +G WSG+ C +CG PI +G + +N +
Sbjct: 136 GATAIFSCNSGYTLVGSRVRECMANGLWSGSEVRCLAGHCGTPEPIVNGHING-ENYSYR 194
Query: 432 GARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGS 491
G+ +Y C F L+G R C + W G+ P C+ C P + ++ ++ + + G+
Sbjct: 195 GS-VVYQCNAGFRLIGMSVRICQQDHHWSGKTPFCVLVSCGHPGSPPHSQMSGDSYTVGA 253
Query: 492 LASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVN---CGTPTIHKGSFVLINGTTTY 548
+ Y+C L G+++ C L G W+G P C + CG P I + + +
Sbjct: 254 VVRYSCIGKRTLVGNSTRMCGLDGHWTGSLPHCSGTSVGVCGDPGIPAHG-IRLGDSFDP 312
Query: 549 GSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFDYYVHS 608
G++ +F+CE + L G+ E C +G WS P C + SC P PS + D V S
Sbjct: 313 GTVMRFSCEAGHVLRGSSERTCQANGSWSGSQPECGVISCGNPGTPSNARVVFSDGLVFS 372
Query: 609 T-INFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLG 667
+ I + C G+ G + C +G W+G P C I+CG P +P + L N +
Sbjct: 373 SSIVYECREGYYATGLLSRHCSVNGTWTGSDPECLVINCGD-PGIPANGLRLGNDFRY-N 430
Query: 668 SVIQYSCTTNYRLVGPVRR--TCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRS 725
+ Y C Y + +CT++ W+ + P C+ + C P + V
Sbjct: 431 KTVTYQCVPGYMMESHRVSVLSCTKDRTWNGTKPVCKALMCKPPPLIPNGKV-------- 482
Query: 726 HGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDC 785
VG+ + G+ V Y C +GY++ ++ TCE NG W+G P C V C
Sbjct: 483 -------------VGSDFMWGSSVTYACLEGYQLSLPAVFTCEGNGSWTGELPQCFPVFC 529
Query: 786 GNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKE--- 842
G+PG G+ Y ++ + C L G RR CQ +GTWS P C +
Sbjct: 530 GDPGVPSRGR--REDRGFSYRSSVSFSCHPPLVLVGSPRRFCQSDGTWSGTQPSCIDPTL 587
Query: 843 ITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVC 902
TC DP G+ + +G ++C++GY L+G TRTC+ W+GT P C
Sbjct: 588 TTCADPGV---PQFGIQNNSQGYQVGSTVLFRCQKGYLLQGSTTRTCLPNLTWSGTPPDC 644
Query: 903 IPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQ-RVGPFLRKCLDDGRWSGEEPS 961
+P CR P + + + ++ G ++ Y C + + G R C DG W+G+ P
Sbjct: 645 VPHHCRQPETPTHANVGALDLPSM-GYTLIYSCQEGFSLKGGSEHRTCKADGSWTGKPPI 703
Query: 962 C 962
C
Sbjct: 704 C 704
Score = 281 bits (688), Expect = 1e-74
Identities = 177/609 (29%), Positives = 255/609 (41%), Gaps = 42/609 (6%)
Query: 364 ILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWS--GAPPSCKYVNCGGLTPIEDGD 421
I Y ++++ C G+ G + C+ +G WS + P+C+ ++CG L +G
Sbjct: 68 IFETQYQFQAQLMLICDPGYYYTGQRVIRCQANGKWSLGDSTPTCRIISCGELPIPPNGH 127
Query: 422 VALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNAS 481
I + +GA A++SC +TLVG+ R C G+W G RCL C P + N
Sbjct: 128 --RIGTLSVYGATAIFSCNSGYTLVGSRVRECMANGLWSGSEVRCLAGHCGTPEPIVNGH 185
Query: 482 VTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTIHKGSFVL 541
+ + Y C G L G + C WSG P C V+CG P S +
Sbjct: 186 INGENYSYRGSVVYQCNAGFRLIGMSVRICQQDHHWSGKTPFCVLVSCGHPGSPPHS-QM 244
Query: 542 INGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTS---CPEPEVPSGGY 598
+ T G++ +++C L G +C DG W+ +P C TS C +P +P+ G
Sbjct: 245 SGDSYTVGAVVRYSCIGKRTLVGNSTRMCGLDGHWTGSLPHCSGTSVGVCGDPGIPAHGI 304
Query: 599 MEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTME 658
+ + + F CEAGH L G CQ +G WSG P C I CG P P
Sbjct: 305 RLGDSFDPGTVMRFSCEAGHVLRGSSERTCQANGSWSGSQPECGVISCGN-PGTPSNARV 363
Query: 659 LLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVS 718
+ + S I Y C Y G + R C+ W+ S P C I C DP + +
Sbjct: 364 VFSDGLVFSSSIVYECREGYYATGLLSRHCSVNGTWTGSDPECLVINCGDPGIPANGL-- 421
Query: 719 VTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLS--TCEDNGQWSGT 776
+GN +R V Y+C GY + +S +C + W+GT
Sbjct: 422 -------------------RLGNDFRYNKTVTYQCVPGYMMESHRVSVLSCTKDRTWNGT 462
Query: 777 TPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLE 836
P C+ + C P I NGKV + +G++ Y C E ++L C+ NG+W+ E
Sbjct: 463 KPVCKALMCKPPPLIPNGKVV--GSDFMWGSSVTYACLEGYQLSLPAVFTCEGNGSWTGE 520
Query: 837 PPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWN 896
P C + C DP + S + C L G R C S G W+
Sbjct: 521 LPQCFPVFCGDPGVPSRGRR----EDRGFSYRSSVSFSCHPPLVLVGSPRRFCQSDGTWS 576
Query: 897 GTVPVCIP---IDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDG 953
GT P CI C PG + G S G + GS+V + C Y G R CL +
Sbjct: 577 GTQPSCIDPTLTTCADPGVPQFGIQNNSQGYQV-GSTVLFRCQKGYLLQGSTTRTCLPNL 635
Query: 954 RWSGEEPSC 962
WSG P C
Sbjct: 636 TWSGTPPDC 644
Score = 263 bits (645), Expect = 2e-69
Identities = 186/614 (30%), Positives = 255/614 (41%), Gaps = 47/614 (7%)
Query: 364 ILGNDYDVGSRIVYKCPEG-HMLLG-DKSRHCKKDGFWS--GAPPSCKYVNCGGLTPI-- 417
+ G +Y VG++ +Y C EG H+ G + + C G WS PP C V C ++ I
Sbjct: 1 VFGKEYTVGTKAMYSCSEGYHLQAGAEATAECLDTGLWSNRNVPPQCVPVTCPDVSSISV 60
Query: 418 EDGDVALI-DNRTTHGARALYSCRENFTLVGNPERTCGDEGIWD-GEA-PRCLFDWCPDP 474
E G LI + + A+ + C + G C G W G++ P C C +
Sbjct: 61 EHGRWRLIFETQYQFQAQLMLICDPGYYYTGQRVIRCQANGKWSLGDSTPTCRIISCGEL 120
Query: 475 PAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTP-T 533
P N G+ A ++C +G+ L GS C G WSG C +CGTP
Sbjct: 121 PIPPNGHRIGTLSVYGATAIFSCNSGYTLVGSRVRECMANGLWSGSEVRCLAGHCGTPEP 180
Query: 534 IHKGSFVLINGTT-TYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPE 592
I G ING +Y + C + L G +C +D WS P C L SC P
Sbjct: 181 IVNGH---INGENYSYRGSVVYQCNAGFRLIGMSVRICQQDHHWSGKTPFCVLVSCGHPG 237
Query: 593 VPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKL--P 650
P M Y V + + + C L+G +C DG W+G P C G P
Sbjct: 238 SPPHSQMSGDSYTVGAVVRYSCIGKRTLVGNSTRMCGLDGHWTGSLPHCSGTSVGVCGDP 297
Query: 651 TLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPI 710
+P + L + G+V+++SC + L G RTC WS S P C I C +P
Sbjct: 298 GIPAHGIR-LGDSFDPGTVMRFSCEAGHVLRGSSERTCQANGSWSGSQPECGVISCGNP- 355
Query: 711 VAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDN 770
S V +D L+ +S + Y C +GY G C N
Sbjct: 356 -GTPSNARVVFSD-----GLVFSSS-------------IVYECREGYYATGLLSRHCSVN 396
Query: 771 GQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEG--VIRRMCQ 828
G W+G+ P C ++CG+PG NG + L N Y T YQC + +E V C
Sbjct: 397 GTWTGSDPECLVINCGDPGIPANG-LRL-GNDFRYNKTVTYQCVPGYMMESHRVSVLSCT 454
Query: 829 ENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRT 888
++ TW+ P+CK + C P I G VV S G Y C GY L T
Sbjct: 455 KDRTWNGTKPVCKALMCKPPPL-IPNGK---VVGSDFMWGSSVTYACLEGYQLSLPAVFT 510
Query: 889 CISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRK 948
C G W G +P C P+ C PG G+ + + SSV + C VG R
Sbjct: 511 CEGNGSWTGELPQCFPVFCGDPGVPSRGR--REDRGFSYRSSVSFSCHPPLVLVGSPRRF 568
Query: 949 CLDDGRWSGEEPSC 962
C DG WSG +PSC
Sbjct: 569 CQSDGTWSGTQPSC 582
Score = 237 bits (581), Expect = 1e-61
Identities = 154/504 (30%), Positives = 223/504 (44%), Gaps = 40/504 (7%)
Query: 352 TCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNC 411
+CG P ++ + G+ Y VG+ + Y C L+G+ +R C DG W+G+ P C +
Sbjct: 232 SCGHPGSPPHSQMSGDSYTVGAVVRYSCIGKRTLVGNSTRMCGLDGHWTGSLPHCSGTSV 291
Query: 412 G--GLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFD 469
G G I + L D+ G +SC L G+ ERTC G W G P C
Sbjct: 292 GVCGDPGIPAHGIRLGDS-FDPGTVMRFSCEAGHVLRGSSERTCQANGSWSGSQPECGVI 350
Query: 470 WCPDPPAVSNASVTV-NGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVN 528
C +P SNA V +G S Y C G+ +G S C++ G W+G P C +N
Sbjct: 351 SCGNPGTPSNARVVFSDGLVFSSSIVYECREGYYATGLLSRHCSVNGTWTGSDPECLVIN 410
Query: 529 CGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNG--AEELVCNRDGKWSYDIPSCELT 586
CG P I L N Y + C P Y + L C +D W+ P C+
Sbjct: 411 CGDPGIPANGLRLGN-DFRYNKTVTYQCVPGYMMESHRVSVLSCTKDRTWNGTKPVCKAL 469
Query: 587 SCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDC 646
C P + G + D+ S++ + C G++L C+ +G W+G+ P C + C
Sbjct: 470 MCKPPPLIPNGKVVGSDFMWGSSVTYACLEGYQLSLPAVFTCEGNGSWTGELPQCFPVFC 529
Query: 647 GKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEE--- 703
G P +P G ++ SV +SC LVG RR C + WS + P C +
Sbjct: 530 GD-PGVPSRGRREDRGFSYRSSV-SFSCHPPLVLVGSPRRFCQSDGTWSGTQPSCIDPTL 587
Query: 704 IRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGES 763
C+DP V + I + S G Y++G+ V +RC+KGY + G +
Sbjct: 588 TTCADPGVPQFGI-----QNNSQG---------------YQVGSTVLFRCQKGYLLQGST 627
Query: 764 LSTCEDNGQWSGTTPTCQYVDC---GNPGRIENGKVTLPSNATFYGATAFYQCDENWELE 820
TC N WSGT P C C P G + LPS G T Y C E + L+
Sbjct: 628 TRTCLPNLTWSGTPPDCVPHHCRQPETPTHANVGALDLPS----MGYTLIYSCQEGFSLK 683
Query: 821 -GVIRRMCQENGTWSLEPPICKEI 843
G R C+ +G+W+ +PPIC E+
Sbjct: 684 GGSEHRTCKADGSWTGKPPICLEV 707
Score = 207 bits (506), Expect = 1e-52
Identities = 140/492 (28%), Positives = 211/492 (42%), Gaps = 45/492 (9%)
Query: 487 HKAGSLASYTCENGHILSGSTSVT--CTLGGAWSG--VPPSCKYVNC---GTPTIHKGSF 539
+ G+ A Y+C G+ L T C G WS VPP C V C + ++ G +
Sbjct: 6 YTVGTKAMYSCSEGYHLQAGAEATAECLDTGLWSNRNVPPQCVPVTCPDVSSISVEHGRW 65
Query: 540 VLINGTT-TYGSIAQFTCEPDYWLNGAEELVCNRDGKWSY--DIPSCELTSCPEPEVPSG 596
LI T + + C+P Y+ G + C +GKWS P+C + SC E +P
Sbjct: 66 RLIFETQYQFQAQLMLICDPGYYYTGQRVIRCQANGKWSLGDSTPTCRIISCGELPIPPN 125
Query: 597 GYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGT 656
G+ +T F C +G+ L+G C +G WSG C CG + G
Sbjct: 126 GHRIGTLSVYGATAIFSCNSGYTLVGSRVRECMANGLWSGSEVRCLAGHCGTPEPIVNGH 185
Query: 657 MELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSI 716
+ N ++ GSV+ Y C +RL+G R C ++ WS +P C + C P S
Sbjct: 186 INGEN-YSYRGSVV-YQCNAGFRLIGMSVRICQQDHHWSGKTPFCVLVSCGHPGSPPHSQ 243
Query: 717 VSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGT 776
+S G++Y +GA+V+Y C ++G S C +G W+G+
Sbjct: 244 MS---------------------GDSYTVGAVVRYSCIGKRTLVGNSTRMCGLDGHWTGS 282
Query: 777 TPTCQYVD---CGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTW 833
P C CG+PG +G + L ++ G + C+ L G R CQ NG+W
Sbjct: 283 LPHCSGTSVGVCGDPGIPAHG-IRL-GDSFDPGTVMRFSCEAGHVLRGSSERTCQANGSW 340
Query: 834 SLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKG 893
S P C I+C +P A +V + L Y+C GY G +R C G
Sbjct: 341 SGSQPECGVISCGNPGTPSNAR---VVFSDGLVFSSSIVYECREGYYATGLLSRHCSVNG 397
Query: 894 QWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLR--KCLD 951
W G+ P C+ I+C PG NG + + N + +V Y C+ Y + C
Sbjct: 398 TWTGSDPECLVINCGDPGIPANG-LRLGNDFR-YNKTVTYQCVPGYMMESHRVSVLSCTK 455
Query: 952 DGRWSGEEPSCE 963
D W+G +P C+
Sbjct: 456 DRTWNGTKPVCK 467
Score = 184 bits (449), Expect = 1e-45
Identities = 113/362 (31%), Positives = 160/362 (44%), Gaps = 12/362 (3%)
Query: 352 TCGSPDKLLNTTILGNDYDV-GSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVN 410
+CG+P N ++ +D V S IVY+C EG+ G SRHC +G W+G+ P C +N
Sbjct: 351 SCGNPGTPSNARVVFSDGLVFSSSIVYECREGYYATGLLSRHCSVNGTWTGSDPECLVIN 410
Query: 411 CGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPER--TCGDEGIWDGEAPRCLF 468
CG P + + N + Y C + + + +C + W+G P C
Sbjct: 411 CGD--PGIPANGLRLGNDFRYNKTVTYQCVPGYMMESHRVSVLSCTKDRTWNGTKPVCKA 468
Query: 469 DWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVN 528
C PP + N V + GS +Y C G+ LS TC G+W+G P C V
Sbjct: 469 LMCKPPPLIPNGKVVGSDFMWGSSVTYACLEGYQLSLPAVFTCEGNGSWTGELPQCFPVF 528
Query: 529 CGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSC---EL 585
CG P + G + Y S F+C P L G+ C DG WS PSC L
Sbjct: 529 CGDPGVPSRGRREDRGFS-YRSSVSFSCHPPLVLVGSPRRFCQSDGTWSGTQPSCIDPTL 587
Query: 586 TSCPEPEVPSGGYME-AFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYI 644
T+C +P VP G + Y V ST+ F C+ G+ L G C + WSG P C
Sbjct: 588 TTCADPGVPQFGIQNNSQGYQVGSTVLFRCQKGYLLQGSTTRTCLPNLTWSGTPPDCVPH 647
Query: 645 DCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVG-PVRRTCTEEFQWSDSSPRCEE 703
C + T + + L+ +G + YSC + L G RTC + W+ P C E
Sbjct: 648 HCRQPETPTHANVGALD-LPSMGYTLIYSCQEGFSLKGGSEHRTCKADGSWTGKPPICLE 706
Query: 704 IR 705
+R
Sbjct: 707 VR 708
Score = 110 bits (264), Expect = 3e-23
Identities = 75/237 (31%), Positives = 107/237 (45%), Gaps = 17/237 (7%)
Query: 740 GNTYRIGALVKYRCEKGYKVIG--ESLSTCEDNGQWSGTT--PTCQYVDCGNPGRI--EN 793
G Y +G Y C +GY + E+ + C D G WS P C V C + I E+
Sbjct: 3 GKEYTVGTKAMYSCSEGYHLQAGAEATAECLDTGLWSNRNVPPQCVPVTCPDVSSISVEH 62
Query: 794 GKVTLPSNATF-YGATAFYQCDENWELEGVIRRMCQENGTWSL--EPPICKEITCPDPSA 850
G+ L + + A CD + G CQ NG WSL P C+ I+C +
Sbjct: 63 GRWRLIFETQYQFQAQLMLICDPGYYYTGQRVIRCQANGKWSLGDSTPTCRIISCGE--L 120
Query: 851 QIKAGSGLLVVTSTLSI-GGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRS 909
I + TLS+ G A + C GY L G + R C++ G W+G+ C+ C +
Sbjct: 121 PIPPNGHRI---GTLSVYGATAIFSCNSGYTLVGSRVRECMANGLWSGSEVRCLAGHCGT 177
Query: 910 PGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCELAT 966
P I NG I N S + SV Y C + ++ +G +R C D WSG+ P C L +
Sbjct: 178 PEPIVNGHINGENYS--YRGSVVYQCNAGFRLIGMSVRICQQDHHWSGKTPFCVLVS 232
Score = 85.8 bits (203), Expect = 7e-16
Identities = 56/185 (30%), Positives = 79/185 (42%), Gaps = 10/185 (5%)
Query: 347 QYLPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSC 406
Q P CG P + S + + C +L+G R C+ DG WSG PSC
Sbjct: 523 QCFPVFCGDPGVPSRGRREDRGFSYRSSVSFSCHPPLVLVGSPRRFCQSDGTWSGTQPSC 582
Query: 407 KYVNCGGLTPIEDGDVAL--IDNRTTH---GARALYSCRENFTLVGNPERTCGDEGIWDG 461
LT D V I N + G+ L+ C++ + L G+ RTC W G
Sbjct: 583 IDPT---LTTCADPGVPQFGIQNNSQGYQVGSTVLFRCQKGYLLQGSTTRTCLPNLTWSG 639
Query: 462 EAPRCLFDWCPDPPAVSNASV-TVNGHKAGSLASYTCENGHILSG-STSVTCTLGGAWSG 519
P C+ C P ++A+V ++ G Y+C+ G L G S TC G+W+G
Sbjct: 640 TPPDCVPHHCRQPETPTHANVGALDLPSMGYTLIYSCQEGFSLKGGSEHRTCKADGSWTG 699
Query: 520 VPPSC 524
PP C
Sbjct: 700 KPPIC 704
Score = 52.8 bits (121), Expect = 6e-06
Identities = 24/57 (42%), Positives = 30/57 (52%), Gaps = 2/57 (3%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
CG+P P NARV + +V + VYEC EGY G R C++ G WT P C
Sbjct: 352 CGNPGTPSNARVVF--SDGLVFSSSIVYECREGYYATGLLSRHCSVNGTWTGSDPEC 406
Score = 45.6 bits (103), Expect = 0.001
Identities = 23/67 (34%), Positives = 32/67 (47%), Gaps = 2/67 (2%)
Query: 349 LPPTCGSPDKLLNTTILGNDY-DVGSRIVYKCPEGHMLLG-DKSRHCKKDGFWSGAPPSC 406
+P C P+ + + D +G ++Y C EG L G + R CK DG W+G PP C
Sbjct: 645 VPHHCRQPETPTHANVGALDLPSMGYTLIYSCQEGFSLKGGSEHRTCKADGSWTGKPPIC 704
Query: 407 KYVNCGG 413
V G
Sbjct: 705 LEVRPNG 711
Score = 43.6 bits (98), Expect = 0.004
Identities = 23/62 (37%), Positives = 31/62 (50%), Gaps = 4/62 (6%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC-GT 60
CGHP PP++++S ++ G + Y C L G R C L G WT P C GT
Sbjct: 233 CGHPGSPPHSQMS---GDSYTVGAVVRYSCIGKRTLVGNSTRMCGLDGHWTGSLPHCSGT 289
Query: 61 NV 62
+V
Sbjct: 290 SV 291
Score = 41.9 bits (94), Expect = 0.012
Identities = 20/52 (38%), Positives = 28/52 (53%), Gaps = 5/52 (9%)
Query: 2 CGHPAVPPNA-RVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWT 52
CG +PPN R+ + V G A++ C+ GY L G+R REC G W+
Sbjct: 117 CGELPIPPNGHRIGTLS----VYGATAIFSCNSGYTLVGSRVRECMANGLWS 164
Score = 41.5 bits (93), Expect = 0.016
Identities = 18/58 (31%), Positives = 29/58 (50%), Gaps = 3/58 (5%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCG 59
CG P +P + I ++ GT+ + C+ G+ L G+ +R C G W+ P CG
Sbjct: 294 CGDPGIPAHG---IRLGDSFDPGTVMRFSCEAGHVLRGSSERTCQANGSWSGSQPECG 348
Score = 41.5 bits (93), Expect = 0.016
Identities = 20/58 (34%), Positives = 28/58 (48%), Gaps = 3/58 (5%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQ-RECTLRGDWTLEPPFC 58
C P P +A V + ++ G +Y C EG+ L G + R C G WT +PP C
Sbjct: 649 CRQPETPTHANVGALDLPSM--GYTLIYSCQEGFSLKGGSEHRTCKADGSWTGKPPIC 704
Score = 36.3 bits (80), Expect = 0.60
Identities = 19/57 (33%), Positives = 25/57 (43%), Gaps = 3/57 (5%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
CG P N + N EN VY+C+ G+ L G R C W+ + PFC
Sbjct: 175 CGTPEPIVNGHI---NGENYSYRGSVVYQCNAGFRLIGMSVRICQQDHHWSGKTPFC 228
Score = 35.1 bits (77), Expect = 1.4
Identities = 17/57 (29%), Positives = 25/57 (43%), Gaps = 2/57 (3%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C P VP + N + G+ ++ C +GY L G+ R C W+ PP C
Sbjct: 590 CADPGVPQFGIQN--NSQGYQVGSTVLFRCQKGYLLQGSTTRTCLPNLTWSGTPPDC 644
Score = 32.7 bits (71), Expect = 7.4
Identities = 19/57 (33%), Positives = 25/57 (43%), Gaps = 3/57 (5%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C P + PN +V + + G+ Y C EGY+L C G WT E P C
Sbjct: 471 CKPPPLIPNGKVV---GSDFMWGSSVTYACLEGYQLSLPAVFTCEGNGSWTGELPQC 524
>AY017307-1|AAG52948.1| 3389|Homo sapiens CUB and sushi multiple
domains protein 1 short form protein.
Length = 3389
Score = 288 bits (706), Expect = 8e-77
Identities = 169/613 (27%), Positives = 271/613 (44%), Gaps = 44/613 (7%)
Query: 364 ILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWS--GAPPSCKYVNCGGLTPIEDGD 421
+ G+ + G++++ C G+ L G + C+ +G W+ PSC+ +CG PI +G
Sbjct: 2575 VSGSLNEYGAQVLLSCSPGYYLEGWRLLRCQANGTWNIGDERPSCRAGHCGSPDPIVNGH 2634
Query: 422 VALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNAS 481
++ + ++ +Y C F LVG R C + W G+ P C+ C P ++
Sbjct: 2635 IS--GDGFSYRDTVVYQCNPGFRLVGTSVRICLQDHKWSGQTPVCVPITCGHPGNPAHGF 2692
Query: 482 VTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTIHKGSF-- 539
+ + ++TC G++L G + C G WS P+C+ VNC P + +
Sbjct: 2693 TNGSEFNLNDVVNFTCNTGYLLQGVSRAQCRSNGQWSSPLPTCRVVNCSDPGFVENAIRH 2752
Query: 540 --VLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGG 597
+ YG + C+ + L G+ L C +G W +P C SC P VP+
Sbjct: 2753 GQQNFPESFEYGMSILYHCKKGFHLLGSSALTCMANGLWDRSLPKCLAISCGHPGVPANA 2812
Query: 598 YMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYID---CGKLPTLPY 654
+ + + +++ C LIG VCQ+D WSG P C + CG T +
Sbjct: 2813 VLTGELFTYGAVVHYSCRGSESLIGNDTRVCQEDSHWSGALPHCTGNNPGFCGDPGTPAH 2872
Query: 655 GTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEK 714
G+ L S++++SC ++L G RTC WS P CE + C P +
Sbjct: 2873 GSR--LGDDFKTKSLLRFSCEMGHQLRGSPERTCLLNGSWSGLQPVCEAVLCPQPPPVQN 2930
Query: 715 SIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWS 774
V G+ +R G+ + Y C GY++ ++ +CE G W
Sbjct: 2931 GTVE---------------------GSDFRWGSSISYSCMDGYQLSHSAILSCEGRGVWK 2969
Query: 775 GTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWS 834
G P C V CG+PG G+ L + Y + F+QC + L G RR+CQ +GTWS
Sbjct: 2970 GEIPQCLPVFCGDPGIPAEGR--LSGKSFTYKSEVFFQCKSPFILVGSSRRVCQADGTWS 3027
Query: 835 LEPPIC---KEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCIS 891
P C TCPDP G+ + +G ++C +GY+++G TRTC++
Sbjct: 3028 GIQPTCIDPAHNTCPDPGT---PHFGIQNSSRGYEVGSTVFFRCRKGYHIQGSTTRTCLA 3084
Query: 892 KGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRV-GPFLRKCL 950
W+G CIP CR P + + + T FG ++ Y C + G R C
Sbjct: 3085 NLTWSGIQTECIPHACRQPETPAHADVRAIDLPT-FGYTLVYTCHPGFFLAGGSEHRTCK 3143
Query: 951 DDGRWSGEEPSCE 963
D +W+G+ P C+
Sbjct: 3144 ADMKWTGKSPVCK 3156
Score = 279 bits (685), Expect = 3e-74
Identities = 181/651 (27%), Positives = 280/651 (43%), Gaps = 55/651 (8%)
Query: 347 QYLPPTCGSPDKLLNTTILGNDYD-VGSRIVYKCPEGHMLLGDKSRHCKKDGF----WSG 401
+Y P C L N IL VGS++ Y C G+ ++G + C+++ W
Sbjct: 2428 RYAAPYCSLTHPLKNGGILNRTAGAVGSKVHYFCKPGYRMVGHSNATCRRNPLGMYQWDS 2487
Query: 402 APPSCKYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERT--CGDEGIW 459
P C+ V+CG P G+ + N T ++ +Y C E F L + + T C ++G+W
Sbjct: 2488 LTPLCQAVSCG--IPESPGNGSFTGNEFTLDSKVVYECHEGFKLESSQQATAVCQEDGLW 2545
Query: 460 D--GEAPRCLFDWCPDPPAVSNASVT---VNG--HKAGSLASYTCENGHILSGSTSVTCT 512
G+ P C CP A + V V+G ++ G+ +C G+ L G + C
Sbjct: 2546 SNKGKPPMCKPVACPSIEAQLSEHVIWRLVSGSLNEYGAQVLLSCSPGYYLEGWRLLRCQ 2605
Query: 513 LGGAWS--GVPPSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVC 570
G W+ PSC+ +CG+P + +G + Y + C P + L G +C
Sbjct: 2606 ANGTWNIGDERPSCRAGHCGSPDPIVNGHISGDGFS-YRDTVVYQCNPGFRLVGTSVRIC 2664
Query: 571 NRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQ 630
+D KWS P C +C P P+ G+ ++ ++ +NF C G+ L G C+
Sbjct: 2665 LQDHKWSGQTPVCVPITCGHPGNPAHGFTNGSEFNLNDVVNFTCNTGYLLQGVSRAQCRS 2724
Query: 631 DGEWSGDSPTCEYIDC---GKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRT 687
+G+WS PTC ++C G + + + G I Y C + L+G T
Sbjct: 2725 NGQWSSPLPTCRVVNCSDPGFVENAIRHGQQNFPESFEYGMSILYHCKKGFHLLGSSALT 2784
Query: 688 CTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGA 747
C W S P+C I C P V ++++ G + GA
Sbjct: 2785 CMANGLWDRSLPKCLAISCGHPGVPANAVLT---------------------GELFTYGA 2823
Query: 748 LVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVD---CGNPGRIENGKVTLPSNATF 804
+V Y C +IG C+++ WSG P C + CG+PG +G T
Sbjct: 2824 VVHYSCRGSESLIGNDTRVCQEDSHWSGALPHCTGNNPGFCGDPGTPAHGSRLGDDFKT- 2882
Query: 805 YGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTST 864
+ + C+ +L G R C NG+WS P+C+ + CP P ++ G+ V S
Sbjct: 2883 -KSLLRFSCEMGHQLRGSPERTCLLNGSWSGLQPVCEAVLCPQP-PPVQNGT---VEGSD 2937
Query: 865 LSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGS 924
G Y C GY L +C +G W G +P C+P+ C PG G+ +S S
Sbjct: 2938 FRWGSSISYSCMDGYQLSHSAILSCEGRGVWKGEIPQCLPVFCGDPGIPAEGR--LSGKS 2995
Query: 925 TLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC-ELATNEAVDSGT 974
+ S V + C S + VG R C DG WSG +P+C + A N D GT
Sbjct: 2996 FTYKSEVFFQCKSPFILVGSSRRVCQADGTWSGIQPTCIDPAHNTCPDPGT 3046
Score = 252 bits (617), Expect = 5e-66
Identities = 160/562 (28%), Positives = 234/562 (41%), Gaps = 42/562 (7%)
Query: 353 CGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCG 412
CGSPD ++N I G+ + +VY+C G L+G R C +D WSG P C + CG
Sbjct: 2624 CGSPDPIVNGHISGDGFSYRDTVVYQCNPGFRLVGTSVRICLQDHKWSGQTPVCVPITCG 2683
Query: 413 GLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCP 472
P + ++C + L G C G W P C C
Sbjct: 2684 H--PGNPAHGFTNGSEFNLNDVVNFTCNTGYLLQGVSRAQCRSNGQWSSPLPTCRVVNCS 2741
Query: 473 DPPAVSNA-----SVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYV 527
DP V NA + G Y C+ G L GS+++TC G W P C +
Sbjct: 2742 DPGFVENAIRHGQQNFPESFEYGMSILYHCKKGFHLLGSSALTCMANGLWDRSLPKCLAI 2801
Query: 528 NCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTS 587
+CG P + + VL TYG++ ++C L G + VC D WS +P C +
Sbjct: 2802 SCGHPGVPANA-VLTGELFTYGAVVHYSCRGSESLIGNDTRVCQEDSHWSGALPHCTGNN 2860
Query: 588 ---CPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYI 644
C +P P+ G D+ S + F CE GH+L G P C +G WSG P CE +
Sbjct: 2861 PGFCGDPGTPAHGSRLGDDFKTKSLLRFSCEMGHQLRGSPERTCLLNGSWSGLQPVCEAV 2920
Query: 645 DCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEI 704
C + P + GT+E GS I YSC Y+L +C W P+C +
Sbjct: 2921 LCPQPPPVQNGTVE--GSDFRWGSSISYSCMDGYQLSHSAILSCEGRGVWKGEIPQCLPV 2978
Query: 705 RCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESL 764
C DP + ++ R G ++ + V ++C+ + ++G S
Sbjct: 2979 FCGDPGI---------------------PAEGRLSGKSFTYKSEVFFQCKSPFILVGSSR 3017
Query: 765 STCEDNGQWSGTTPTC---QYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEG 821
C+ +G WSG PTC + C +PG G + S G+T F++C + + ++G
Sbjct: 3018 RVCQADGTWSGIQPTCIDPAHNTCPDPGTPHFG-IQNSSRGYEVGSTVFFRCRKGYHIQG 3076
Query: 822 VIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNL 881
R C N TWS C C P A + + + G Y C G+ L
Sbjct: 3077 STTRTCLANLTWSGIQTECIPHACRQPETPAHADVRAIDLP---TFGYTLVYTCHPGFFL 3133
Query: 882 K-GHQTRTCISKGQWNGTVPVC 902
G + RTC + +W G PVC
Sbjct: 3134 AGGSEHRTCKADMKWTGKSPVC 3155
Score = 186 bits (453), Expect = 4e-46
Identities = 116/359 (32%), Positives = 161/359 (44%), Gaps = 12/359 (3%)
Query: 352 TCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVN- 410
+CG P N + G + G+ + Y C L+G+ +R C++D WSGA P C N
Sbjct: 2802 SCGHPGVPANAVLTGELFTYGAVVHYSCRGSESLIGNDTRVCQEDSHWSGALPHCTGNNP 2861
Query: 411 --CGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLF 468
CG G D +T R +SC L G+PERTC G W G P C
Sbjct: 2862 GFCGDPGTPAHGSRLGDDFKTKSLLR--FSCEMGHQLRGSPERTCLLNGSWSGLQPVCEA 2919
Query: 469 DWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVN 528
CP PP V N +V + + GS SY+C +G+ LS S ++C G W G P C V
Sbjct: 2920 VLCPQPPPVQNGTVEGSDFRWGSSISYSCMDGYQLSHSAILSCEGRGVWKGEIPQCLPVF 2979
Query: 529 CGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSC---EL 585
CG P I L + TY S F C+ + L G+ VC DG WS P+C
Sbjct: 2980 CGDPGI-PAEGRLSGKSFTYKSEVFFQCKSPFILVGSSRRVCQADGTWSGIQPTCIDPAH 3038
Query: 586 TSCPEPEVPSGGYMEAF-DYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYI 644
+CP+P P G + Y V ST+ F C G+ + G C + WSG C
Sbjct: 3039 NTCPDPGTPHFGIQNSSRGYEVGSTVFFRCRKGYHIQGSTTRTCLANLTWSGIQTECIPH 3098
Query: 645 DCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLV-GPVRRTCTEEFQWSDSSPRCE 702
C + T + + ++ T G + Y+C + L G RTC + +W+ SP C+
Sbjct: 3099 ACRQPETPAHADVRAIDLPT-FGYTLVYTCHPGFFLAGGSEHRTCKADMKWTGKSPVCK 3156
Score = 167 bits (407), Expect = 1e-40
Identities = 140/548 (25%), Positives = 229/548 (41%), Gaps = 57/548 (10%)
Query: 437 YSCRENFTLVGNPERTC--GDEGIWDGEAPRCLFDWCP--DPPAVSNASVTVNGHKAGSL 492
Y C +TLVG TC + ++G P C CP + S+ + G+
Sbjct: 2286 YQCHPGYTLVGTDILTCKLSSQLQFEGSLPTCEAQ-CPANEVRTGSSGVILSPGYPGNYF 2344
Query: 493 ASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTIHKGSFVLINGTTTYGSIA 552
S TC + + ++T + S V G+ + V+++G T S
Sbjct: 2345 NSQTCSWSIKVEPNYNITIFVDTFQSEKQFDALEVFDGS-SGQSPLLVVLSGNHTEQS-- 2401
Query: 553 QFTCEPD-YWLNGAEELVCNRDG-KWSYDIPSCELTSCPEPEVPSGGYMEAFDYYVHSTI 610
FT + +L + + ++ G K Y P C LT + +GG + V S +
Sbjct: 2402 NFTSRSNQLYLRWSTDHATSKKGFKIRYAAPYCSLTH----PLKNGGILNRTAGAVGSKV 2457
Query: 611 NFHCEAGHKLIGEPNLVCQQDG----EWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHL 666
++ C+ G++++G N C+++ +W +P C+ + CG +P P G L
Sbjct: 2458 HYFCKPGYRMVGHSNATCRRNPLGMYQWDSLTPLCQAVSCG-IPESP-GNGSFTGNEFTL 2515
Query: 667 GSVIQYSCTTNYRLVGPVRRT--CTEEFQWSDSS--PRCEEIRCSDPIVAEKSIVSVTGN 722
S + Y C ++L + T C E+ WS+ P C+ + C I A+ S
Sbjct: 2516 DSKVVYECHEGFKLESSQQATAVCQEDGLWSNKGKPPMCKPVACPS-IEAQLS------- 2567
Query: 723 DRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWS--GTTPTC 780
H + R G+ GA V C GY + G L C+ NG W+ P+C
Sbjct: 2568 ----EHVIWRLVS----GSLNEYGAQVLLSCSPGYYLEGWRLLRCQANGTWNIGDERPSC 2619
Query: 781 QYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPIC 840
+ CG+P I NG ++ + Y T YQC+ + L G R+C ++ WS + P+C
Sbjct: 2620 RAGHCGSPDPIVNGHIS--GDGFSYRDTVVYQCNPGFRLVGTSVRICLQDHKWSGQTPVC 2677
Query: 841 KEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVP 900
ITC P + S ++ ++ C GY L+G C S GQW+ +P
Sbjct: 2678 VPITCGHPGNPAHGFTN----GSEFNLNDVVNFTCNTGYLLQGVSRAQCRSNGQWSSPLP 2733
Query: 901 VCIPIDCRSPGNIENGKIVISNG------STLFGSSVEYYCLSQYQRVGPFLRKCLDDGR 954
C ++C PG +EN I +G S +G S+ Y+C + +G C+ +G
Sbjct: 2734 TCRVVNCSDPGFVEN---AIRHGQQNFPESFEYGMSILYHCKKGFHLLGSSALTCMANGL 2790
Query: 955 WSGEEPSC 962
W P C
Sbjct: 2791 WDRSLPKC 2798
Score = 153 bits (370), Expect = 4e-36
Identities = 92/301 (30%), Positives = 137/301 (45%), Gaps = 13/301 (4%)
Query: 350 PPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYV 409
P CG P + + LG+D+ S + + C GH L G R C +G WSG P C+ V
Sbjct: 2861 PGFCGDPGTPAHGSRLGDDFKTKSLLRFSCEMGHQLRGSPERTCLLNGSWSGLQPVCEAV 2920
Query: 410 NCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFD 469
C P+++G V D R G+ YSC + + L + +C G+W GE P+CL
Sbjct: 2921 LCPQPPPVQNGTVEGSDFR--WGSSISYSCMDGYQLSHSAILSCEGRGVWKGEIPQCLPV 2978
Query: 470 WCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSC---KY 526
+C DP + ++ S + C++ IL GS+ C G WSG+ P+C +
Sbjct: 2979 FCGDPGIPAEGRLSGKSFTYKSEVFFQCKSPFILVGSSRRVCQADGTWSGIQPTCIDPAH 3038
Query: 527 VNCGTP-TIHKGSFVLINGTTTY--GSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSC 583
C P T H F + N + Y GS F C Y + G+ C + WS C
Sbjct: 3039 NTCPDPGTPH---FGIQNSSRGYEVGSTVFFRCRKGYHIQGSTTRTCLANLTWSGIQTEC 3095
Query: 584 ELTSCPEPEVPSGGYMEAFDYYVHS-TINFHCEAGHKLI-GEPNLVCQQDGEWSGDSPTC 641
+C +PE P+ + A D T+ + C G L G + C+ D +W+G SP C
Sbjct: 3096 IPHACRQPETPAHADVRAIDLPTFGYTLVYTCHPGFFLAGGSEHRTCKADMKWTGKSPVC 3155
Query: 642 E 642
+
Sbjct: 3156 K 3156
Score = 83.0 bits (196), Expect = 5e-15
Identities = 54/187 (28%), Positives = 80/187 (42%), Gaps = 8/187 (4%)
Query: 345 ICQYLPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPP 404
I Q LP CG P + G + S + ++C +L+G R C+ DG WSG P
Sbjct: 2972 IPQCLPVFCGDPGIPAEGRLSGKSFTYKSEVFFQCKSPFILVGSSRRVCQADGTWSGIQP 3031
Query: 405 SCKYVNCGGLTPIEDGDVAL-IDNRTTH---GARALYSCRENFTLVGNPERTCGDEGIWD 460
+C ++ T + G I N + G+ + CR+ + + G+ RTC W
Sbjct: 3032 TC--IDPAHNTCPDPGTPHFGIQNSSRGYEVGSTVFFRCRKGYHIQGSTTRTCLANLTWS 3089
Query: 461 GEAPRCLFDWCPDPPAVSNASV-TVNGHKAGSLASYTCENGHILS-GSTSVTCTLGGAWS 518
G C+ C P ++A V ++ G YTC G L+ GS TC W+
Sbjct: 3090 GIQTECIPHACRQPETPAHADVRAIDLPTFGYTLVYTCHPGFFLAGGSEHRTCKADMKWT 3149
Query: 519 GVPPSCK 525
G P CK
Sbjct: 3150 GKSPVCK 3156
Score = 58.8 bits (136), Expect = 1e-07
Identities = 64/242 (26%), Positives = 92/242 (38%), Gaps = 18/242 (7%)
Query: 353 CGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHC--KKDG--FWSGAPPSCKY 408
C P ++N T +G D+ +GS I Y+C G+ +L S C DG W PSC
Sbjct: 1565 CFDPGNIMNGTRVGTDFKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLPSCN- 1623
Query: 409 VNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLF 468
CGG +G V L N H A C + T+ E + + A L
Sbjct: 1624 APCGGQYTGSEG-VVLSPN-YPHNYTAGQICLYSITV--PKEFVVFGQFAYFQTALNDLA 1679
Query: 469 DWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGG---AWSGVPPSCK 525
+ A + +++G +G N +L S + G + VP +
Sbjct: 1680 ELFDGTHAQARLLSSLSGSHSGETLPLATSNQILLRFSAKSGASARGFHFVYQAVPRTSD 1739
Query: 526 YVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVC----NRDGKWSYDIP 581
P G I + GSI +F C P Y L G+ L C N +W+ IP
Sbjct: 1740 TQCSSVPEPRYGR--RIGSEFSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQWNDTIP 1797
Query: 582 SC 583
SC
Sbjct: 1798 SC 1799
Score = 56.0 bits (129), Expect = 7e-07
Identities = 22/70 (31%), Positives = 41/70 (58%), Gaps = 1/70 (1%)
Query: 578 YDIPSCELTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGD 637
Y+ + E SC +P +P G+ D+ + ST+ F C+ G+ L + LVC+++ +W+
Sbjct: 864 YESVTLESDSCLDPGIPVNGHRHGGDFGIRSTVTFSCDPGYTLSDDEPLVCERNHQWNHA 923
Query: 638 SPTCEYIDCG 647
P+C+ + CG
Sbjct: 924 LPSCDAL-CG 932
Score = 55.6 bits (128), Expect = 9e-07
Identities = 34/90 (37%), Positives = 46/90 (51%), Gaps = 6/90 (6%)
Query: 571 NRDG-KWSYDIPSCELTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQ 629
NR G K +Y + EL +CP+P GYM DY V +++F C G+ LIG P L CQ
Sbjct: 2073 NRQGFKLAYQ--AYELQNCPDPPPFQNGYMINSDYSVGQSVSFECYPGYILIGHPVLTCQ 2130
Query: 630 Q--DGEWSGDSPTCEYIDCGKLPTLPYGTM 657
+ W+ P C+ CG T GT+
Sbjct: 2131 HGINRNWNYPFPRCD-APCGYNVTSQNGTI 2159
Score = 53.2 bits (122), Expect = 5e-06
Identities = 20/60 (33%), Positives = 33/60 (55%)
Query: 584 ELTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEY 643
E C +P +P+ G + T+ F C A +L+GE + CQQ+ +WSG+ P+C +
Sbjct: 524 EKGGCGDPGIPAYGKRTGSSFLHGDTLTFECPAAFELVGERVITCQQNNQWSGNKPSCVF 583
Score = 46.0 bits (104), Expect = 7e-04
Identities = 19/67 (28%), Positives = 35/67 (52%), Gaps = 1/67 (1%)
Query: 740 GNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLP 799
G+++ G + + C ++++GE + TC+ N QWSG P+C + C +G + P
Sbjct: 541 GSSFLHGDTLTFECPAAFELVGERVITCQQNNQWSGNKPSCVF-SCFFNFTASSGIILSP 599
Query: 800 SNATFYG 806
+ YG
Sbjct: 600 NYPEEYG 606
Score = 43.2 bits (97), Expect = 0.005
Identities = 67/291 (23%), Positives = 114/291 (39%), Gaps = 42/291 (14%)
Query: 650 PTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTC---TEEF-QWSDSSPRCEEIR 705
P +P + + +G+ +Q+SC NY L G TC TE WSD P C
Sbjct: 352 PGIPENGRRAGSDFSRVGANVQFSCEDNYVLQGSKSITCQRVTETLAAWSDHRPICRART 411
Query: 706 CSDPIVAEKSIVS-----VTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVI 760
C + +++ V D +H +I T+D V A ++ E+GY +
Sbjct: 412 CGSNLRGPSGVITSPNYPVQYEDNAHCVWVITTTDPDKVIKL----AFEEFELERGYDTL 467
Query: 761 GESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELE 820
T D G+ G T + YV G+ + + V++ + + Q D++
Sbjct: 468 -----TVGDAGK-VGDTRSVLYVLTGS--SVPDLIVSMSNQMWLH-----LQSDDSIGSP 514
Query: 821 GVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYN 880
G + + QE +E C + P+ + GS L G ++C +
Sbjct: 515 G-FKAVYQE-----IEKGGCGDPGI--PAYGKRTGSSFL-------HGDTLTFECPAAFE 559
Query: 881 LKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSV 931
L G + TC QW+G P C+ C +G I+ N +G+++
Sbjct: 560 LVGERVITCQQNNQWSGNKPSCV-FSCFFNFTASSGIILSPNYPEEYGNNM 609
Score = 43.2 bits (97), Expect = 0.005
Identities = 23/70 (32%), Positives = 32/70 (45%), Gaps = 2/70 (2%)
Query: 585 LTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQD--GEWSGDSPTCE 642
L +C EP +PS Y V+ ++F CE G+ L G ++ C W+ SP C
Sbjct: 1914 LAACQEPALPSNSIKIGDRYMVNDVLSFQCEPGYTLQGRSHISCMPGTVRRWNYPSPLCI 1973
Query: 643 YIDCGKLPTL 652
G L TL
Sbjct: 1974 ATCGGTLSTL 1983
Score = 42.3 bits (95), Expect = 0.009
Identities = 15/35 (42%), Positives = 24/35 (68%)
Query: 550 SIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCE 584
S F+C+P Y L+ E LVC R+ +W++ +PSC+
Sbjct: 894 STVTFSCDPGYTLSDDEPLVCERNHQWNHALPSCD 928
Score = 41.9 bits (94), Expect = 0.012
Identities = 29/120 (24%), Positives = 48/120 (40%), Gaps = 8/120 (6%)
Query: 297 VDGELVSKPSWGKDQPNNYNGEQNCVVLDGGRGWLWNDVGCNLDYLHWICQYLPPTCGSP 356
VD +++ K G P + + N + L + + G ++ + I TC P
Sbjct: 1340 VDSDILLKEWSGSALPEDIHSTFNSLTLQFDSDFFISKSGFSIQFSTSIAA----TCNDP 1395
Query: 357 DKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDG---FWSGAPPSCKYVNCGG 413
N T G+ + G + ++C G+ L G C + FW PP+C CGG
Sbjct: 1396 GMPQNGTRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTC-IAACGG 1454
Score = 41.5 bits (93), Expect = 0.016
Identities = 21/71 (29%), Positives = 35/71 (49%), Gaps = 1/71 (1%)
Query: 352 TCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNC 411
+C P +N G D+ + S + + C G+ L D+ C+++ W+ A PSC + C
Sbjct: 873 SCLDPGIPVNGHRHGGDFGIRSTVTFSCDPGYTLSDDEPLVCERNHQWNHALPSCDAL-C 931
Query: 412 GGLTPIEDGDV 422
GG + G V
Sbjct: 932 GGYIQGKSGTV 942
Score = 41.5 bits (93), Expect = 0.016
Identities = 20/66 (30%), Positives = 32/66 (48%), Gaps = 1/66 (1%)
Query: 740 GNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLP 799
G + I + V + C+ GY + + CE N QW+ P+C + CG + ++G V P
Sbjct: 887 GGDFGIRSTVTFSCDPGYTLSDDEPLVCERNHQWNHALPSCDAL-CGGYIQGKSGTVLSP 945
Query: 800 SNATFY 805
FY
Sbjct: 946 GFPDFY 951
Score = 41.5 bits (93), Expect = 0.016
Identities = 21/73 (28%), Positives = 33/73 (45%), Gaps = 5/73 (6%)
Query: 739 VGNTYRIGALVKYRCEKGYKVIGESLSTC----EDNGQWSGTTPTCQYVDCGNPGRIENG 794
VG +++G+ + Y+C+ GYK++ S TC + W P+C CG G
Sbjct: 1577 VGTDFKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLPSCN-APCGGQYTGSEG 1635
Query: 795 KVTLPSNATFYGA 807
V P+ Y A
Sbjct: 1636 VVLSPNYPHNYTA 1648
Score = 41.1 bits (92), Expect = 0.021
Identities = 24/90 (26%), Positives = 38/90 (42%), Gaps = 6/90 (6%)
Query: 330 WLWNDVGCNLDYLHWICQYLPP-TCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGD 388
W D + + + LP TCG+P ++L + G +++G +I Y C G++L G
Sbjct: 121 WFTTDFAVSAQGFKALYEVLPSHTCGNPGEILKGVLHGTRFNIGDKIRYSCLPGYILEGH 180
Query: 389 KSRHC----KKDGFWSGAPPSCKYVN-CGG 413
C W P C+ CGG
Sbjct: 181 AILTCIVSPGNGASWDFPAPFCRAEGACGG 210
Score = 40.7 bits (91), Expect = 0.028
Identities = 22/74 (29%), Positives = 32/74 (43%), Gaps = 4/74 (5%)
Query: 587 SCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGE---WSGDSPTCEY 643
+C +P +P G T+ F C+ G++L G+ + C Q W D PTC
Sbjct: 1391 TCNDPGMPQNGTRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTC-I 1449
Query: 644 IDCGKLPTLPYGTM 657
CG T P G +
Sbjct: 1450 AACGGNLTGPAGVI 1463
Score = 40.7 bits (91), Expect = 0.028
Identities = 16/41 (39%), Positives = 26/41 (63%), Gaps = 2/41 (4%)
Query: 743 YRIGALVKYRCEKGYKVIGESLSTCEDNG--QWSGTTPTCQ 781
+ IG VKY+C GY ++G + TC+ + Q+ G+ PTC+
Sbjct: 2278 FEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPTCE 2318
Score = 40.3 bits (90), Expect = 0.037
Identities = 21/76 (27%), Positives = 38/76 (50%), Gaps = 5/76 (6%)
Query: 2 CGHPAVPPN-ARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGT 60
CG P P + +R+ ++ ++ + C+ G++L G+ +R C L G W+ P C
Sbjct: 2864 CGDPGTPAHGSRLG----DDFKTKSLLRFSCEMGHQLRGSPERTCLLNGSWSGLQPVCEA 2919
Query: 61 NVAFRKPANQSTTVRG 76
+ + P Q+ TV G
Sbjct: 2920 VLCPQPPPVQNGTVEG 2935
Score = 39.9 bits (89), Expect = 0.049
Identities = 21/66 (31%), Positives = 30/66 (45%), Gaps = 3/66 (4%)
Query: 584 ELTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGE--WSGDSPTC 641
+L C +P VP+ F + V ++ F C G++L G L C G WS P C
Sbjct: 1042 DLEPCDDPGVPAFSRRIGFHFGVGDSLTFSCFLGYRLEGATKLTCLGGGRRVWSAPLPRC 1101
Query: 642 EYIDCG 647
+CG
Sbjct: 1102 -VAECG 1106
Score = 39.1 bits (87), Expect = 0.085
Identities = 16/56 (28%), Positives = 28/56 (50%)
Query: 353 CGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKY 408
CG P G+ + G + ++CP L+G++ C+++ WSG PSC +
Sbjct: 528 CGDPGIPAYGKRTGSSFLHGDTLTFECPAAFELVGERVITCQQNNQWSGNKPSCVF 583
Score = 39.1 bits (87), Expect = 0.085
Identities = 21/62 (33%), Positives = 28/62 (45%), Gaps = 3/62 (4%)
Query: 471 CPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLG--GAWSGVPPSCKYVN 528
CPDPP N + + + G S+ C G+IL G +TC G W+ P C
Sbjct: 2089 CPDPPPFQNGYMINSDYSVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYPFPRCD-AP 2147
Query: 529 CG 530
CG
Sbjct: 2148 CG 2149
Score = 38.7 bits (86), Expect = 0.11
Identities = 22/75 (29%), Positives = 32/75 (42%), Gaps = 5/75 (6%)
Query: 588 CPEPEVPSGGYMEAFDYY-VHSTINFHCEAGHKLIGEPNLVCQQDGE----WSGDSPTCE 642
C +P +P G D+ V + + F CE + L G ++ CQ+ E WS P C
Sbjct: 349 CLDPGIPENGRRAGSDFSRVGANVQFSCEDNYVLQGSKSITCQRVTETLAAWSDHRPICR 408
Query: 643 YIDCGKLPTLPYGTM 657
CG P G +
Sbjct: 409 ARTCGSNLRGPSGVI 423
Score = 38.7 bits (86), Expect = 0.11
Identities = 23/79 (29%), Positives = 41/79 (51%), Gaps = 8/79 (10%)
Query: 785 CGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEG----VIRRMCQENGTWSLEPPIC 840
C +PG ENG+ S+ + GA + C++N+ L+G +R+ + WS PIC
Sbjct: 349 CLDPGIPENGR-RAGSDFSRVGANVQFSCEDNYVLQGSKSITCQRVTETLAAWSDHRPIC 407
Query: 841 KEITCPDPSAQIKAGSGLL 859
+ TC + ++ SG++
Sbjct: 408 RARTC---GSNLRGPSGVI 423
Score = 38.7 bits (86), Expect = 0.11
Identities = 20/74 (27%), Positives = 33/74 (44%), Gaps = 5/74 (6%)
Query: 737 RDVGNTYRIGALVKYRCEKGYKVIGESLSTCED----NGQWSGTTPTCQYVDCGNPGRIE 792
R +G+ + G++V++ C GY + G + C+ QW+ T P+C V C
Sbjct: 1752 RRIGSEFSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQWNDTIPSC-VVPCSGNFTQR 1810
Query: 793 NGKVTLPSNATFYG 806
G + P YG
Sbjct: 1811 RGTILSPGYPEPYG 1824
Score = 38.7 bits (86), Expect = 0.11
Identities = 19/63 (30%), Positives = 29/63 (46%), Gaps = 3/63 (4%)
Query: 739 VGNTYRIGALVKYRCEKGYKVIGESLSTCED--NGQWSGTTPTCQYVDCGNPGRIENGKV 796
+ + Y +G V + C GY +IG + TC+ N W+ P C CG +NG +
Sbjct: 2101 INSDYSVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYPFPRCD-APCGYNVTSQNGTI 2159
Query: 797 TLP 799
P
Sbjct: 2160 YSP 2162
Score = 37.9 bits (84), Expect = 0.20
Identities = 22/67 (32%), Positives = 33/67 (49%), Gaps = 7/67 (10%)
Query: 471 CPDPPAVSNASVTVNGH-KAGSLASYTCENGHILSGSTSVTC-----TLGGAWSGVPPSC 524
C DP N + + G+ ++CE+ ++L GS S+TC TL AWS P C
Sbjct: 349 CLDPGIPENGRRAGSDFSRVGANVQFSCEDNYVLQGSKSITCQRVTETL-AAWSDHRPIC 407
Query: 525 KYVNCGT 531
+ CG+
Sbjct: 408 RARTCGS 414
Score = 37.9 bits (84), Expect = 0.20
Identities = 21/70 (30%), Positives = 31/70 (44%), Gaps = 4/70 (5%)
Query: 549 GSIAQFTCEPDYWLNGAEELVCNRD----GKWSYDIPSCELTSCPEPEVPSGGYMEAFDY 604
G+ QF+CE +Y L G++ + C R WS P C +C G + + +Y
Sbjct: 369 GANVQFSCEDNYVLQGSKSITCQRVTETLAAWSDHRPICRARTCGSNLRGPSGVITSPNY 428
Query: 605 YVHSTINFHC 614
V N HC
Sbjct: 429 PVQYEDNAHC 438
Score = 37.5 bits (83), Expect = 0.26
Identities = 18/56 (32%), Positives = 29/56 (51%), Gaps = 2/56 (3%)
Query: 907 CRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
C PG GK + S L G ++ + C + ++ VG + C + +WSG +PSC
Sbjct: 528 CGDPGIPAYGKR--TGSSFLHGDTLTFECPAAFELVGERVITCQQNNQWSGNKPSC 581
Score = 37.5 bits (83), Expect = 0.26
Identities = 22/64 (34%), Positives = 25/64 (39%), Gaps = 4/64 (6%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC-GT 60
CGHP VP NA + E G + Y C L G R C W+ P C G
Sbjct: 2803 CGHPGVPANA---VLTGELFTYGAVVHYSCRGSESLIGNDTRVCQEDSHWSGALPHCTGN 2859
Query: 61 NVAF 64
N F
Sbjct: 2860 NPGF 2863
Score = 36.7 bits (81), Expect = 0.45
Identities = 23/86 (26%), Positives = 40/86 (46%), Gaps = 9/86 (10%)
Query: 336 GCNLDYLHWICQYLPPT----CGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSR 391
G + H++ Q +P T C S + +G+++ GS + ++C G++L G +
Sbjct: 1721 GASARGFHFVYQAVPRTSDTQCSSVPEPRYGRRIGSEFSAGSIVRFECNPGYLLQGSTAL 1780
Query: 392 HCKKD----GFWSGAPPSCKYVNCGG 413
HC+ W+ PSC V C G
Sbjct: 1781 HCQSVPNALAQWNDTIPSC-VVPCSG 1805
Score = 36.7 bits (81), Expect = 0.45
Identities = 51/238 (21%), Positives = 83/238 (34%), Gaps = 15/238 (6%)
Query: 471 CPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGA--WSGVPPSCKYVN 528
C +P SN+ + + + S+ CE G+ L G + ++C G W+ P C
Sbjct: 1917 CQEPALPSNSIKIGDRYMVNDVLSFQCEPGYTLQGRSHISCMPGTVRRWNYPSPLC-IAT 1975
Query: 529 CGTPTIHKGSFVLING-TTTYGSIAQFTCEPDYWLN-GAEELVCNRDGKWSYDIPSCELT 586
CG G +L G +Y + T + GA N + ++D E+
Sbjct: 1976 CGGTLSTLGGVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTEANHDF--LEIQ 2033
Query: 587 SCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDC 646
+ P P G D H LI + Q + E +C
Sbjct: 2034 NGPYHTSPMIGQFSGTDLPAALLSTTH----ETLIHFYSDHSQNRQGFKLAYQAYELQNC 2089
Query: 647 GKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEF--QWSDSSPRCE 702
P P+ ++N +G + + C Y L+G TC W+ PRC+
Sbjct: 2090 PDPP--PFQNGYMINSDYSVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYPFPRCD 2145
Score = 36.7 bits (81), Expect = 0.45
Identities = 19/63 (30%), Positives = 30/63 (47%), Gaps = 4/63 (6%)
Query: 584 ELTSC-PEPEVPSGGYM-EAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDG--EWSGDSP 639
+L C P P VP + E D+ + + + C G+ L+G L C+ ++ G P
Sbjct: 2256 QLKKCQPPPAVPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLP 2315
Query: 640 TCE 642
TCE
Sbjct: 2316 TCE 2318
Score = 36.3 bits (80), Expect = 0.60
Identities = 20/59 (33%), Positives = 30/59 (50%), Gaps = 5/59 (8%)
Query: 785 CGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMC-QENGT--WSLEPPIC 840
C +PG +NG T ++ G T +QCD ++L+G + C Q N W +PP C
Sbjct: 1392 CNDPGMPQNG--TRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTC 1448
Score = 35.9 bits (79), Expect = 0.79
Identities = 23/87 (26%), Positives = 40/87 (45%), Gaps = 5/87 (5%)
Query: 736 NRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQ--WSGTTPTCQYVDCGNPGRIEN 793
+R +G + +G + + C GY++ G + TC G+ WS P C +CG +
Sbjct: 1055 SRRIGFHFGVGDSLTFSCFLGYRLEGATKLTCLGGGRRVWSAPLPRC-VAECGASVKGNE 1113
Query: 794 GKVTLPSNATFYGATAFYQCDENWELE 820
G + P+ + Y T ++C E E
Sbjct: 1114 GTLLSPNFPSNYDNT--HECIYKIETE 1138
Score = 35.9 bits (79), Expect = 0.79
Identities = 20/64 (31%), Positives = 29/64 (45%), Gaps = 6/64 (9%)
Query: 471 CPDPPAVSNASVTVN--GHKAGSLASYTCENGHILSGSTSVTCTLGG--AWSGVPPSCKY 526
C DP + N + GH ++ Y+C G+ + GS ++TC G W PSC
Sbjct: 1218 CEDP-GIPNYGYRIRDEGHFTDTVVLYSCNPGYAMHGSNTLTCLSGDRRVWDKPLPSC-I 1275
Query: 527 VNCG 530
CG
Sbjct: 1276 AECG 1279
Score = 35.9 bits (79), Expect = 0.79
Identities = 19/63 (30%), Positives = 28/63 (44%), Gaps = 4/63 (6%)
Query: 471 CPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCT-LGGA--WSGVPPSCKYV 527
C DP N + + +AG ++ C+ G+ L G +TC L W PP+C
Sbjct: 1392 CNDPGMPQNGTRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTC-IA 1450
Query: 528 NCG 530
CG
Sbjct: 1451 ACG 1453
Score = 35.9 bits (79), Expect = 0.79
Identities = 21/72 (29%), Positives = 31/72 (43%), Gaps = 5/72 (6%)
Query: 471 CPDPPAVSNASVTV--NGHKAGSLASYTCENGHILSGSTSVTCTLGG--AWSGVPPSCKY 526
C PPAV A + + + G Y C G+ L G+ +TC L + G P+C+
Sbjct: 2260 CQPPPAVPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPTCE- 2318
Query: 527 VNCGTPTIHKGS 538
C + GS
Sbjct: 2319 AQCPANEVRTGS 2330
Score = 35.5 bits (78), Expect = 1.0
Identities = 17/67 (25%), Positives = 30/67 (44%), Gaps = 3/67 (4%)
Query: 532 PTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYD--IPSCELTSCP 589
P + + + + G ++ C P Y L G + L C + ++ +P+CE CP
Sbjct: 2264 PAVPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPTCE-AQCP 2322
Query: 590 EPEVPSG 596
EV +G
Sbjct: 2323 ANEVRTG 2329
Score = 35.5 bits (78), Expect = 1.0
Identities = 16/57 (28%), Positives = 23/57 (40%), Gaps = 3/57 (5%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
CGHP P + N + + C+ GY L G + +C G W+ P C
Sbjct: 2682 CGHPGNPAHG---FTNGSEFNLNDVVNFTCNTGYLLQGVSRAQCRSNGQWSSPLPTC 2735
Score = 35.1 bits (77), Expect = 1.4
Identities = 21/80 (26%), Positives = 29/80 (36%)
Query: 471 CPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCG 530
C DP + T + G ++ C L G +TC WSG PSC +
Sbjct: 528 CGDPGIPAYGKRTGSSFLHGDTLTFECPAAFELVGERVITCQQNNQWSGNKPSCVFSCFF 587
Query: 531 TPTIHKGSFVLINGTTTYGS 550
T G + N YG+
Sbjct: 588 NFTASSGIILSPNYPEEYGN 607
Score = 35.1 bits (77), Expect = 1.4
Identities = 22/96 (22%), Positives = 35/96 (36%), Gaps = 7/96 (7%)
Query: 639 PTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEE----FQW 694
P C +P YG + GS++++ C Y L G C QW
Sbjct: 1735 PRTSDTQCSSVPEPRYGRR--IGSEFSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQW 1792
Query: 695 SDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTL 730
+D+ P C + CS + + G +G+ L
Sbjct: 1793 NDTIPSC-VVPCSGNFTQRRGTILSPGYPEPYGNNL 1827
Score = 35.1 bits (77), Expect = 1.4
Identities = 18/59 (30%), Positives = 26/59 (44%), Gaps = 2/59 (3%)
Query: 646 CGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTC--TEEFQWSDSSPRCE 702
C P +P M + +G ++Y C Y LVG TC + + Q+ S P CE
Sbjct: 2260 CQPPPAVPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPTCE 2318
Score = 34.7 bits (76), Expect = 1.8
Identities = 24/63 (38%), Positives = 31/63 (49%), Gaps = 8/63 (12%)
Query: 844 TCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCI-SKG---QWNGTV 899
TC +P +K G+L T +IG + Y C GY L+GH TCI S G W+
Sbjct: 144 TCGNPGEILK---GVLHGTR-FNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFPA 199
Query: 900 PVC 902
P C
Sbjct: 200 PFC 202
Score = 34.7 bits (76), Expect = 1.8
Identities = 25/82 (30%), Positives = 35/82 (42%), Gaps = 13/82 (15%)
Query: 469 DWCPDPPAVSNASVTVNGHKAG------SLASYTCENGHILSGSTSVTCTLGGAWSGVPP 522
D C DP + VNGH+ G S +++C+ G+ LS + C W+ P
Sbjct: 872 DSCLDP------GIPVNGHRHGGDFGIRSTVTFSCDPGYTLSDDEPLVCERNHQWNHALP 925
Query: 523 SCKYVNCGTPTIHKGSFVLING 544
SC + CG K VL G
Sbjct: 926 SCDAL-CGGYIQGKSGTVLSPG 946
Score = 34.7 bits (76), Expect = 1.8
Identities = 17/69 (24%), Positives = 31/69 (44%), Gaps = 4/69 (5%)
Query: 582 SCELTSCPEPEVPSGGY-MEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGE--WSGDS 638
S +L C +P +P+ GY + ++ + + + C G+ + G L C W
Sbjct: 1212 SFDLVKCEDPGIPNYGYRIRDEGHFTDTVVLYSCNPGYAMHGSNTLTCLSGDRRVWDKPL 1271
Query: 639 PTCEYIDCG 647
P+C +CG
Sbjct: 1272 PSC-IAECG 1279
Score = 34.7 bits (76), Expect = 1.8
Identities = 20/75 (26%), Positives = 32/75 (42%), Gaps = 5/75 (6%)
Query: 861 VTSTLSIGGEAHYQCERGYNLKGHQTRTCIS----KGQWNGTVPVCIPIDCRSPGNIENG 916
+ S S G ++C GY L+G C S QWN T+P C+ + C G
Sbjct: 1754 IGSEFSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQWNDTIPSCV-VPCSGNFTQRRG 1812
Query: 917 KIVISNGSTLFGSSV 931
I+ +G+++
Sbjct: 1813 TILSPGYPEPYGNNL 1827
Score = 34.7 bits (76), Expect = 1.8
Identities = 20/66 (30%), Positives = 33/66 (50%), Gaps = 4/66 (6%)
Query: 489 AGSLASYTCENGHILSGSTSVTC-TLGGA---WSGVPPSCKYVNCGTPTIHKGSFVLING 544
AGS+ + C G++L GST++ C ++ A W+ PSC G T +G+ +
Sbjct: 1760 AGSIVRFECNPGYLLQGSTALHCQSVPNALAQWNDTIPSCVVPCSGNFTQRRGTILSPGY 1819
Query: 545 TTTYGS 550
YG+
Sbjct: 1820 PEPYGN 1825
Score = 34.7 bits (76), Expect = 1.8
Identities = 22/83 (26%), Positives = 32/83 (38%), Gaps = 4/83 (4%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTN 61
CG P N +S + VY+C+ G+ L G R C W+ + P C
Sbjct: 2624 CGSPDPIVNGHIS---GDGFSYRDTVVYQCNPGFRLVGTSVRICLQDHKWSGQTPVC-VP 2679
Query: 62 VAFRKPANQSTTVRGGAAANGND 84
+ P N + G+ N ND
Sbjct: 2680 ITCGHPGNPAHGFTNGSEFNLND 2702
Score = 34.3 bits (75), Expect = 2.4
Identities = 14/38 (36%), Positives = 16/38 (42%)
Query: 431 HGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLF 468
HG + C F LVG TC W G P C+F
Sbjct: 546 HGDTLTFECPAAFELVGERVITCQQNNQWSGNKPSCVF 583
Score = 34.3 bits (75), Expect = 2.4
Identities = 21/61 (34%), Positives = 28/61 (45%), Gaps = 4/61 (6%)
Query: 473 DPPAVSNASVTVNGH-KAGSLASYTCENGHILSGSTSVTCTLGG--AWSGVPPSCKYVNC 529
D P V S + H G +++C G+ L G+T +TC GG WS P C C
Sbjct: 1047 DDPGVPAFSRRIGFHFGVGDSLTFSCFLGYRLEGATKLTCLGGGRRVWSAPLPRC-VAEC 1105
Query: 530 G 530
G
Sbjct: 1106 G 1106
Score = 34.3 bits (75), Expect = 2.4
Identities = 18/72 (25%), Positives = 33/72 (45%), Gaps = 3/72 (4%)
Query: 353 CGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKK--DGFWSGAPPSCKYVN 410
C P N ++ +DY VG + ++C G++L+G C+ + W+ P C
Sbjct: 2089 CPDPPPFQNGYMINSDYSVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYPFPRCD-AP 2147
Query: 411 CGGLTPIEDGDV 422
CG ++G +
Sbjct: 2148 CGYNVTSQNGTI 2159
Score = 34.3 bits (75), Expect = 2.4
Identities = 26/84 (30%), Positives = 38/84 (45%), Gaps = 10/84 (11%)
Query: 845 CPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTC--ISKGQWNGTVPVC 902
C P A +A +L IG YQC GY L G TC S+ Q+ G++P C
Sbjct: 2260 CQPPPAVPQAE--MLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPTC 2317
Query: 903 IPIDCRSPGN-IENGK--IVISNG 923
+ + P N + G +++S G
Sbjct: 2318 ---EAQCPANEVRTGSSGVILSPG 2338
Score = 33.9 bits (74), Expect = 3.2
Identities = 24/87 (27%), Positives = 36/87 (41%), Gaps = 7/87 (8%)
Query: 646 CGKLPTLP-YGTMELLNGTTHL-GSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEE 703
CG P +P YG G++ L G + + C + LVG TC + QWS + P C
Sbjct: 528 CGD-PGIPAYGKR---TGSSFLHGDTLTFECPAAFELVGERVITCQQNNQWSGNKPSC-V 582
Query: 704 IRCSDPIVAEKSIVSVTGNDRSHGHTL 730
C A I+ +G+ +
Sbjct: 583 FSCFFNFTASSGIILSPNYPEEYGNNM 609
Score = 33.9 bits (74), Expect = 3.2
Identities = 24/76 (31%), Positives = 31/76 (40%), Gaps = 7/76 (9%)
Query: 845 CPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCIS--KGQWNGTVPVC 902
CPDP + G ++ S S+G ++C GY L GH TC WN P C
Sbjct: 2089 CPDPPP-FQNG---YMINSDYSVGQSVSFECYPGYILIGHPVLTCQHGINRNWNYPFPRC 2144
Query: 903 IPIDCRSPGNIENGKI 918
C +NG I
Sbjct: 2145 -DAPCGYNVTSQNGTI 2159
Score = 33.5 bits (73), Expect = 4.2
Identities = 22/73 (30%), Positives = 36/73 (49%), Gaps = 10/73 (13%)
Query: 717 VSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTC-EDNGQ--W 773
++ T ND R D+R+ G+T V ++C+ GY++ G++ TC + N + W
Sbjct: 1388 IAATCNDPGMPQNGTRYGDSREAGDT------VTFQCDPGYQLQGQAKITCVQLNNRFFW 1441
Query: 774 SGTTPTCQYVDCG 786
PTC CG
Sbjct: 1442 QPDPPTC-IAACG 1453
Score = 33.5 bits (73), Expect = 4.2
Identities = 19/60 (31%), Positives = 26/60 (43%), Gaps = 6/60 (10%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTL---RGDWTLEPPFC 58
C P +P N + E AG ++CD GY+L G + C R W +PP C
Sbjct: 1392 CNDPGMPQNGTRYGDSRE---AGDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTC 1448
Score = 33.1 bits (72), Expect = 5.6
Identities = 19/65 (29%), Positives = 30/65 (46%), Gaps = 5/65 (7%)
Query: 353 CGSPDKLLNTTILGNDYD-VGSRIVYKCPEGHMLLGDKSRHCKKD----GFWSGAPPSCK 407
C P N G+D+ VG+ + + C + ++L G KS C++ WS P C+
Sbjct: 349 CLDPGIPENGRRAGSDFSRVGANVQFSCEDNYVLQGSKSITCQRVTETLAAWSDHRPICR 408
Query: 408 YVNCG 412
CG
Sbjct: 409 ARTCG 413
Score = 33.1 bits (72), Expect = 5.6
Identities = 21/99 (21%), Positives = 40/99 (40%), Gaps = 8/99 (8%)
Query: 527 VNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGK--WSYDIPSC- 583
V C P I + + + ++ ++C P Y ++G+ L C + W +PSC
Sbjct: 1216 VKCEDPGIPNYGYRIRDEGHFTDTVVLYSCNPGYAMHGSNTLTCLSGDRRVWDKPLPSCI 1275
Query: 584 -----ELTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAG 617
++ + + S GY +D +H T + G
Sbjct: 1276 AECGGQIHAATSGRILSPGYPAPYDNNLHCTWIIEADPG 1314
Score = 33.1 bits (72), Expect = 5.6
Identities = 18/65 (27%), Positives = 32/65 (49%), Gaps = 5/65 (7%)
Query: 587 SCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVC--QQDGE--WSGDSPTCE 642
+C +P G D+ + STI + C++G+K++ ++ C DG+ W P+C
Sbjct: 1564 ACFDPGNIMNGTRVGTDFKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLPSCN 1623
Query: 643 YIDCG 647
CG
Sbjct: 1624 -APCG 1627
Score = 33.1 bits (72), Expect = 5.6
Identities = 17/68 (25%), Positives = 32/68 (47%), Gaps = 3/68 (4%)
Query: 734 SDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDN--GQWSGTTPTCQYVDCGNPGRI 791
S++ +G+ Y + ++ ++CE GY + G S +C +W+ +P C CG
Sbjct: 1924 SNSIKIGDRYMVNDVLSFQCEPGYTLQGRSHISCMPGTVRRWNYPSPLC-IATCGGTLST 1982
Query: 792 ENGKVTLP 799
G + P
Sbjct: 1983 LGGVILSP 1990
Score = 32.7 bits (71), Expect = 7.4
Identities = 15/57 (26%), Positives = 23/57 (40%), Gaps = 3/57 (5%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
CG P +P + + + + G +EC +EL G R C W+ P C
Sbjct: 528 CGDPGIPAYGKRT---GSSFLHGDTLTFECPAAFELVGERVITCQQNNQWSGNKPSC 581
Score = 32.3 bits (70), Expect = 9.7
Identities = 15/57 (26%), Positives = 26/57 (45%), Gaps = 3/57 (5%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
CG P +P R+S ++ + ++C + L G+ +R C G W+ P C
Sbjct: 2980 CGDPGIPAEGRLS---GKSFTYKSEVFFQCKSPFILVGSSRRVCQADGTWSGIQPTC 3033
>AF308289-1|AAG48257.1| 481|Homo sapiens serologically defined
breast cancer antigen NY-BR-38 protein.
Length = 481
Score = 248 bits (607), Expect = 8e-65
Identities = 151/522 (28%), Positives = 227/522 (43%), Gaps = 56/522 (10%)
Query: 432 GARALYSCRENFTLVGNPERTCGDEGIWDGEA-PRCLFDWCPDPPAVSNASVTVNGHKAG 490
G++ + C E + LVG+ TC G W+ ++ P+C+ CP+PP + N V
Sbjct: 9 GSKVQFFCNEGYELVGDSSWTCQKSGKWNKKSNPKCMPAKCPEPPLLENQLVLKELTTEV 68
Query: 491 SLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTIHKGSFVLINGTTTYGS 550
+ +++C+ GH+L G + + C W+ P CK V C P + + + +GS
Sbjct: 69 GVVTFSCKEGHVLQGPSVLKCLPSQQWNDSFPVCKIVLCTPPPLISFGVPIPSSALHFGS 128
Query: 551 IAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFDYYVHSTI 610
+++C ++L G +C DG WS +P C CP+PE G ++ ST
Sbjct: 129 TVKYSCVGGFFLRGNSTTLCQPDGTWSSPLPECVPVECPQPEEIPNGIIDVQGLAYLSTA 188
Query: 611 NFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVI 670
+ C+ G +L+G +C ++G W G PTC+ I+C K + G + H G +
Sbjct: 189 LYTCKPGFELVGNTTTLCGENGHWLGGKPTCKAIECLKPKEILNGKFSYTD--LHYGQTV 246
Query: 671 QYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTL 730
YSC +RL GP TC E W +P C I C P E V
Sbjct: 247 TYSCNRGFRLEGPSALTCLETGDWDVDAPSCNAIHCDSPQPIENGFVE------------ 294
Query: 731 IRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGR 790
G Y GA++ Y C G++V G ++ TCE++G WS + PTC +DCG P
Sbjct: 295 ---------GADYSYGAIIIYSCFPGFQVAGHAMQTCEESG-WSSSIPTCMPIDCGLPPH 344
Query: 791 IENGKVTLPSNATFYGATAFYQ----CDENWELE-GVIRRMCQENGTWSLEPPICKEITC 845
I+ G T +A + + CD + L G + + TW E T
Sbjct: 345 IDFGACTKLKDARDILSKKRHDGSSICDSSPSLSFGAVAK------TW--------ENTK 390
Query: 846 PDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPI 905
P+ +S G Y C GY L G+ C G WNG+ P CI I
Sbjct: 391 ESPATH----------SSNFLYGTMVSYTCNPGYELLGNPVLICQEDGTWNGSAPSCISI 440
Query: 906 DCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLR 947
+C P ENG + + T GS+V+Y C + G LR
Sbjct: 441 ECDLPTAPENGFLRFT--ETSMGSAVQYSCKPGHILAGSDLR 480
Score = 219 bits (534), Expect = 6e-56
Identities = 135/482 (28%), Positives = 207/482 (42%), Gaps = 34/482 (7%)
Query: 366 GNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWS-GAPPSCKYVNCGGLTPIEDGDVAL 424
G +++VGS++ + C EG+ L+GD S C+K G W+ + P C C P+ + + L
Sbjct: 3 GENFEVGSKVQFFCNEGYELVGDSSWTCQKSGKWNKKSNPKCMPAKCPE-PPLLENQLVL 61
Query: 425 IDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVS-NASVT 483
+ T G +SC+E L G C W+ P C C PP +S +
Sbjct: 62 KELTTEVGV-VTFSCKEGHVLQGPSVLKCLPSQQWNDSFPVCKIVLCTPPPLISFGVPIP 120
Query: 484 VNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTIHKGSFVLIN 543
+ GS Y+C G L G+++ C G WS P C V C P + +
Sbjct: 121 SSALHFGSTVKYSCVGGFFLRGNSTTLCQPDGTWSSPLPECVPVECPQPEEIPNGIIDVQ 180
Query: 544 GTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFD 603
G Y S A +TC+P + L G +C +G W P+C+ C +P+ G D
Sbjct: 181 G-LAYLSTALYTCKPGFELVGNTTTLCGENGHWLGGKPTCKAIECLKPKEILNGKFSYTD 239
Query: 604 YYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGT 663
+ T+ + C G +L G L C + G+W D+P+C I C + G +E
Sbjct: 240 LHYGQTVTYSCNRGFRLEGPSALTCLETGDWDVDAPSCNAIHCDSPQPIENGFVE--GAD 297
Query: 664 THLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDP-------IVAEKSI 716
G++I YSC +++ G +TC EE WS S P C I C P K
Sbjct: 298 YSYGAIIIYSCFPGFQVAGHAMQTC-EESGWSSSIPTCMPIDCGLPPHIDFGACTKLKDA 356
Query: 717 VSVTGNDRSHGHTLIRTSDNRDVG-------NT----------YRIGALVKYRCEKGYKV 759
+ R G ++ +S + G NT + G +V Y C GY++
Sbjct: 357 RDILSKKRHDGSSICDSSPSLSFGAVAKTWENTKESPATHSSNFLYGTMVSYTCNPGYEL 416
Query: 760 IGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWEL 819
+G + C+++G W+G+ P+C ++C P ENG L T G+ Y C L
Sbjct: 417 LGNPVLICQEDGTWNGSAPSCISIECDLPTAPENG--FLRFTETSMGSAVQYSCKPGHIL 474
Query: 820 EG 821
G
Sbjct: 475 AG 476
Score = 183 bits (446), Expect = 3e-45
Identities = 114/365 (31%), Positives = 166/365 (45%), Gaps = 32/365 (8%)
Query: 599 MEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDS-PTCEYIDCGKLPTLPYGTM 657
M+ ++ V S + F C G++L+G+ + CQ+ G+W+ S P C C + P L +
Sbjct: 1 MKGENFEVGSKVQFFCNEGYELVGDSSWTCQKSGKWNKKSNPKCMPAKCPEPPLLE-NQL 59
Query: 658 ELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIV 717
L TT +G V+ +SC + L GP C QW+DS P C+ + C+ P +
Sbjct: 60 VLKELTTEVG-VVTFSCKEGHVLQGPSVLKCLPSQQWNDSFPVCKIVLCTPPPLI----- 113
Query: 718 SVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTT 777
S G + + G+ VKY C G+ + G S + C+ +G WS
Sbjct: 114 -------SFGVPI--------PSSALHFGSTVKYSCVGGFFLRGNSTTLCQPDGTWSSPL 158
Query: 778 PTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEP 837
P C V+C P I NG + + A Y +TA Y C +EL G +C ENG W
Sbjct: 159 PECVPVECPQPEEIPNGIIDVQGLA--YLSTALYTCKPGFELVGNTTTLCGENGHWLGGK 216
Query: 838 PICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNG 897
P CK I C P + +G T L G Y C RG+ L+G TC+ G W+
Sbjct: 217 PTCKAIECLKPKEIL---NGKFSYTD-LHYGQTVTYSCNRGFRLEGPSALTCLETGDWDV 272
Query: 898 TVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSG 957
P C I C SP IENG + +G+ + Y C +Q G ++ C + G WS
Sbjct: 273 DAPSCNAIHCDSPQPIENG--FVEGADYSYGAIIIYSCFPGFQVAGHAMQTCEESG-WSS 329
Query: 958 EEPSC 962
P+C
Sbjct: 330 SIPTC 334
Score = 182 bits (442), Expect = 8e-45
Identities = 136/483 (28%), Positives = 204/483 (42%), Gaps = 60/483 (12%)
Query: 488 KAGSLASYTCENGHILSGSTSVTCTLGGAWSGVP-PSCKYVNCGTPTIHKGSFVLINGTT 546
+ GS + C G+ L G +S TC G W+ P C C P + + VL TT
Sbjct: 7 EVGSKVQFFCNEGYELVGDSSWTCQKSGKWNKKSNPKCMPAKCPEPPLLENQLVLKELTT 66
Query: 547 TYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSC-PEPEVPSGGYMEAFDYY 605
G + F+C+ + L G L C +W+ P C++ C P P + G + + +
Sbjct: 67 EVG-VVTFSCKEGHVLQGPSVLKCLPSQQWNDSFPVCKIVLCTPPPLISFGVPIPSSALH 125
Query: 606 VHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTH 665
ST+ + C G L G +CQ DG WS P C ++C + +P G +++ G +
Sbjct: 126 FGSTVKYSCVGGFFLRGNSTTLCQPDGTWSSPLPECVPVECPQPEEIPNGIIDV-QGLAY 184
Query: 666 LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRS 725
L + + Y+C + LVG C E W P C+ I C P S T D
Sbjct: 185 LSTAL-YTCKPGFELVGNTTTLCGENGHWLGGKPTCKAIECLKPKEILNGKFSYT--DLH 241
Query: 726 HGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDC 785
+G T V Y C +G+++ G S TC + G W P+C + C
Sbjct: 242 YGQT-------------------VTYSCNRGFRLEGPSALTCLETGDWDVDAPSCNAIHC 282
Query: 786 GNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITC 845
+P IENG V + YGA Y C +++ G + C+E+G WS P C I C
Sbjct: 283 DSPQPIENGFVEGADYS--YGAIIIYSCFPGFQVAGHAMQTCEESG-WSSSIPTCMPIDC 339
Query: 846 PDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPI 905
P I G+ C + LK R +SK + +G+ +C
Sbjct: 340 GLPP-HIDFGA------------------CTK---LK--DARDILSKKRHDGS-SICDSS 374
Query: 906 DCRSPGNI----ENGKIVISNGST--LFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEE 959
S G + EN K + S+ L+G+ V Y C Y+ +G + C +DG W+G
Sbjct: 375 PSLSFGAVAKTWENTKESPATHSSNFLYGTMVSYTCNPGYELLGNPVLICQEDGTWNGSA 434
Query: 960 PSC 962
PSC
Sbjct: 435 PSC 437
Score = 177 bits (431), Expect = 2e-43
Identities = 97/308 (31%), Positives = 132/308 (42%), Gaps = 5/308 (1%)
Query: 349 LPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKY 408
+P C P L N +L + + C EGH+L G C W+ + P CK
Sbjct: 45 MPAKCPEPPLLENQLVLKELTTEVGVVTFSCKEGHVLQGPSVLKCLPSQQWNDSFPVCKI 104
Query: 409 VNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLF 468
V C P+ V + + G+ YSC F L GN C +G W P C+
Sbjct: 105 VLCTP-PPLISFGVPIPSSALHFGSTVKYSCVGGFFLRGNSTTLCQPDGTWSSPLPECVP 163
Query: 469 DWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVN 528
CP P + N + V G S A YTC+ G L G+T+ C G W G P+CK +
Sbjct: 164 VECPQPEEIPNGIIDVQGLAYLSTALYTCKPGFELVGNTTTLCGENGHWLGGKPTCKAIE 223
Query: 529 CGTPT-IHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTS 587
C P I G F + YG ++C + L G L C G W D PSC
Sbjct: 224 CLKPKEILNGKFSYTD--LHYGQTVTYSCNRGFRLEGPSALTCLETGDWDVDAPSCNAIH 281
Query: 588 CPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCG 647
C P+ G++E DY + I + C G ++ G C++ G WS PTC IDCG
Sbjct: 282 CDSPQPIENGFVEGADYSYGAIIIYSCFPGFQVAGHAMQTCEESG-WSSSIPTCMPIDCG 340
Query: 648 KLPTLPYG 655
P + +G
Sbjct: 341 LPPHIDFG 348
Score = 132 bits (320), Expect = 5e-30
Identities = 67/225 (29%), Positives = 111/225 (49%), Gaps = 8/225 (3%)
Query: 740 GNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSG-TTPTCQYVDCGNPGRIENGKVTL 798
G + +G+ V++ C +GY+++G+S TC+ +G+W+ + P C C P +EN ++ L
Sbjct: 3 GENFEVGSKVQFFCNEGYELVGDSSWTCQKSGKWNKKSNPKCMPAKCPEPPLLEN-QLVL 61
Query: 799 PSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGL 858
T G F C E L+G C + W+ P+CK + C P G+
Sbjct: 62 KELTTEVGVVTF-SCKEGHVLQGPSVLKCLPSQQWNDSFPVCKIVLCTPPPL---ISFGV 117
Query: 859 LVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKI 918
+ +S L G Y C G+ L+G+ T C G W+ +P C+P++C P I NG I
Sbjct: 118 PIPSSALHFGSTVKYSCVGGFFLRGNSTTLCQPDGTWSSPLPECVPVECPQPEEIPNGII 177
Query: 919 VISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
+ + L S+ Y C ++ VG C ++G W G +P+C+
Sbjct: 178 DVQGLAYL--STALYTCKPGFELVGNTTTLCGENGHWLGGKPTCK 220
Score = 127 bits (306), Expect = 2e-28
Identities = 76/271 (28%), Positives = 113/271 (41%), Gaps = 19/271 (7%)
Query: 353 CGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCG 412
C P ++LN D G + Y C G L G + C + G W PSC ++C
Sbjct: 224 CLKPKEILNGKFSYTDLHYGQTVTYSCNRGFRLEGPSALTCLETGDWDVDAPSCNAIHCD 283
Query: 413 GLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCP 472
PIE+G V D ++GA +YSC F + G+ +TC + G W P C+ C
Sbjct: 284 SPQPIENGFVEGADY--SYGAIIIYSCFPGFQVAGHAMQTCEESG-WSSSIPTCMPIDCG 340
Query: 473 DPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTC-TLGGAWSGVPPSCKYVNCGT 531
PP + + T L+ + I S S++ + W S
Sbjct: 341 LPPHIDFGACTKLKDARDILSKKRHDGSSICDSSPSLSFGAVAKTWENTKES-------- 392
Query: 532 PTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEP 591
P H +F+ YG++ +TC P Y L G L+C DG W+ PSC C P
Sbjct: 393 PATHSSNFL-------YGTMVSYTCNPGYELLGNPVLICQEDGTWNGSAPSCISIECDLP 445
Query: 592 EVPSGGYMEAFDYYVHSTINFHCEAGHKLIG 622
P G++ + + S + + C+ GH L G
Sbjct: 446 TAPENGFLRFTETSMGSAVQYSCKPGHILAG 476
Score = 67.3 bits (157), Expect = 3e-10
Identities = 28/76 (36%), Positives = 40/76 (52%)
Query: 431 HGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAG 490
+G Y+C + L+GNP C ++G W+G AP C+ C P A N + G
Sbjct: 402 YGTMVSYTCNPGYELLGNPVLICQEDGTWNGSAPSCISIECDLPTAPENGFLRFTETSMG 461
Query: 491 SLASYTCENGHILSGS 506
S Y+C+ GHIL+GS
Sbjct: 462 SAVQYSCKPGHILAGS 477
Score = 62.1 bits (144), Expect = 1e-08
Identities = 31/99 (31%), Positives = 50/99 (50%), Gaps = 3/99 (3%)
Query: 867 IGGEAHYQCERGYNLKGHQTRTCISKGQWNG-TVPVCIPIDCRSPGNIENGKIVISNGST 925
+G + + C GY L G + TC G+WN + P C+P C P +EN ++V+ +T
Sbjct: 8 VGSKVQFFCNEGYELVGDSSWTCQKSGKWNKKSNPKCMPAKCPEPPLLEN-QLVLKELTT 66
Query: 926 LFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCEL 964
G V + C + GP + KCL +W+ P C++
Sbjct: 67 EVGV-VTFSCKEGHVLQGPSVLKCLPSQQWNDSFPVCKI 104
Score = 34.7 bits (76), Expect = 1.8
Identities = 15/42 (35%), Positives = 19/42 (45%)
Query: 17 NEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
+ N + GT+ Y C+ GYEL G C G W P C
Sbjct: 396 HSSNFLYGTMVSYTCNPGYELLGNPVLICQEDGTWNGSAPSC 437
Score = 33.5 bits (73), Expect = 4.2
Identities = 12/35 (34%), Positives = 16/35 (45%)
Query: 24 GTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
G Y C+ G+ L G C GDW ++ P C
Sbjct: 243 GQTVTYSCNRGFRLEGPSALTCLETGDWDVDAPSC 277
>Z99572-7|CAI23063.1| 829|Homo sapiens selectin P (granule membrane
protein 140kDa, antigen CD62) protein.
Length = 829
Score = 235 bits (575), Expect = 6e-61
Identities = 194/764 (25%), Positives = 311/764 (40%), Gaps = 89/764 (11%)
Query: 236 SFDEARKQCQSHGGDLIHGFQGATSSFLTQELERRKAQLKTQLVWIGAQKEPGLTSRTWQ 295
S++ +RK CQ+ DL+ +L + L + WIG +K ++TW
Sbjct: 51 SWNISRKYCQNRYTDLVAIQNKNEIDYLNKVLP-----YYSSYYWIGIRKN----NKTWT 101
Query: 296 WVDGELV---SKPSWGKDQPNNYNGEQNCV---VLDGGRGWLWNDVGCNLDYLHWICQYL 349
WV + +W ++PNN ++CV + WND C L H +C
Sbjct: 102 WVGTKKALTNEAENWADNEPNNKRNNEDCVEIYIKSPSAPGKWNDEHC-LKKKHALCY-- 158
Query: 350 PPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYV 409
T D ++ + G +C E +G+ + C GF+ P C+YV
Sbjct: 159 --TASCQD--MSCSKQG-----------ECLE---TIGNYTCSCYP-GFYG---PECEYV 196
Query: 410 N-CGGLTPIEDGDVALID--NRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRC 466
CG L + + + ++ + C + + + G + C GIW + P+C
Sbjct: 197 RECGELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQC 256
Query: 467 LFDWCPDPPAVSNASVT-VNGHKA---GSLASYTCENGHILSGSTSVTCTLGGAWSGVPP 522
L CP ++T ++ KA S S++CE G L G V CT G W+ P
Sbjct: 257 LAAQCPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASGVWTAPAP 316
Query: 523 SCKYVNCG-TPTIHKGSFVLINGTTT--YGSIAQFTCEPDYWLNGAEELVCNRDGKWSYD 579
CK V C +G+ ++ T YGS +F C+P Y + G + L C G WS
Sbjct: 317 VCKAVQCQHLEAPSEGTMDCVHPLTAFAYGSSCKFECQPGYRVRGLDMLRCIDSGHWSAP 376
Query: 580 IPSCELTSCPEPEVPSGGYME------AFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGE 633
+P+CE SC E P G M+ AF Y + +F C G L G + C G+
Sbjct: 377 LPTCEAISCEPLESPVHGSMDCSPSLRAFQY--DTNCSFRCAEGFMLRGADIVRCDNLGQ 434
Query: 634 WSGDSPTCEYIDCGKLPTLPYGTMELLN--GTTHLGSVIQYSCTTNYRLVGPVRRTCTEE 691
W+ +P C+ + C LP + + G SV ++C LVG C
Sbjct: 435 WTAPAPVCQALQCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLAT 494
Query: 692 FQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKY 751
W+ P C+ I C+ P+++ ++ T ++ + +T ++
Sbjct: 495 GNWNSVPPECQAIPCT-PLLSPQNGTM----------TCVQPLGSSSYKST------CQF 537
Query: 752 RCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFY--GATA 809
C++GY + G C +G+W+ + P C+ + C E G + + G+T
Sbjct: 538 ICDEGYSLSGPERLDCTRSGRWTDSPPMCEAIKCPELFAPEQGSLDCSDTRGEFNVGSTC 597
Query: 810 FYQCDENWELEGVIRRMCQENGTWSLEPPICKEI-TCPDPSAQIKA----GSGLLVVT-- 862
+ CD ++LEG C +G WS PP CK I + P P Q A G G +
Sbjct: 598 HFSCDNGFKLEGPNNVECTTSGRWSATPPTCKGIASLPTPGVQCPALTTPGQGTMYCRHH 657
Query: 863 -STLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVIS 921
T ++ C G+ L G T +C GQW P C + C + + S
Sbjct: 658 PGTFGFNTTCYFGCNAGFTLIGDSTLSCRPSGQWTAVTPACRAVKCSELHVNKPIAMNCS 717
Query: 922 N--GSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
N G+ +GS ++CL G C ++G WS P+C+
Sbjct: 718 NLWGNFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTCQ 761
Score = 89.8 bits (213), Expect = 5e-17
Identities = 52/201 (25%), Positives = 85/201 (42%), Gaps = 7/201 (3%)
Query: 778 PTCQYV-DCGN---PGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTW 833
P C+YV +CG P + N +F +F+ C + +++ G + C +G W
Sbjct: 191 PECEYVRECGELELPQHVLMNCSHPLGNFSFNSQCSFH-CTDGYQVNGPSKLECLASGIW 249
Query: 834 SLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKG 893
+ +PP C CP + L + CE G+ L G + C + G
Sbjct: 250 TNKPPQCLAAQCPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASG 309
Query: 894 QWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLF--GSSVEYYCLSQYQRVGPFLRKCLD 951
W PVC + C+ G + + T F GSS ++ C Y+ G + +C+D
Sbjct: 310 VWTAPAPVCKAVQCQHLEAPSEGTMDCVHPLTAFAYGSSCKFECQPGYRVRGLDMLRCID 369
Query: 952 DGRWSGEEPSCELATNEAVDS 972
G WS P+CE + E ++S
Sbjct: 370 SGHWSAPLPTCEAISCEPLES 390
Score = 40.7 bits (91), Expect = 0.028
Identities = 15/28 (53%), Positives = 17/28 (60%)
Query: 31 CDEGYELFGARQRECTLRGDWTLEPPFC 58
CDEGY L G + +CT G WT PP C
Sbjct: 539 CDEGYSLSGPERLDCTRSGRWTDSPPMC 566
Score = 38.7 bits (86), Expect = 0.11
Identities = 14/35 (40%), Positives = 19/35 (54%)
Query: 24 GTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
G+ + CD G++L G ECT G W+ PP C
Sbjct: 594 GSTCHFSCDNGFKLEGPNNVECTTSGRWSATPPTC 628
Score = 35.9 bits (79), Expect = 0.79
Identities = 16/58 (27%), Positives = 28/58 (48%), Gaps = 1/58 (1%)
Query: 2 CGHPAVPPNARVSIPNE-ENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
CG +P + ++ + N + + C +GY++ G + EC G WT +PP C
Sbjct: 199 CGELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQC 256
Score = 34.7 bits (76), Expect = 1.8
Identities = 18/59 (30%), Positives = 27/59 (45%), Gaps = 1/59 (1%)
Query: 1 RCGHPAVPPNARVSIPNEENIVA-GTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
+C VP ARV+ + ++ + C+EG L GA +C G+W PP C
Sbjct: 446 QCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPEC 504
Score = 34.3 bits (75), Expect = 2.4
Identities = 12/30 (40%), Positives = 16/30 (53%)
Query: 29 YECDEGYELFGARQRECTLRGDWTLEPPFC 58
+ C+EG+ L G +CT G WT P C
Sbjct: 289 FSCEEGFALVGPEVVQCTASGVWTAPAPVC 318
Score = 32.3 bits (70), Expect = 9.7
Identities = 20/62 (32%), Positives = 27/62 (43%), Gaps = 3/62 (4%)
Query: 20 NIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTNVAFRKPANQSTTVRGGAA 79
N G+I + C EG L G+ Q C G W+ P C A ++ T GGA
Sbjct: 722 NFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTC---QAGPLTIQEALTYFGGAV 778
Query: 80 AN 81
A+
Sbjct: 779 AS 780
>Z99572-5|CAI23058.1| 830|Homo sapiens selectin P (granule membrane
protein 140kDa, antigen CD62) protein.
Length = 830
Score = 235 bits (575), Expect = 6e-61
Identities = 194/764 (25%), Positives = 311/764 (40%), Gaps = 89/764 (11%)
Query: 236 SFDEARKQCQSHGGDLIHGFQGATSSFLTQELERRKAQLKTQLVWIGAQKEPGLTSRTWQ 295
S++ +RK CQ+ DL+ +L + L + WIG +K ++TW
Sbjct: 52 SWNISRKYCQNRYTDLVAIQNKNEIDYLNKVLP-----YYSSYYWIGIRKN----NKTWT 102
Query: 296 WVDGELV---SKPSWGKDQPNNYNGEQNCV---VLDGGRGWLWNDVGCNLDYLHWICQYL 349
WV + +W ++PNN ++CV + WND C L H +C
Sbjct: 103 WVGTKKALTNEAENWADNEPNNKRNNEDCVEIYIKSPSAPGKWNDEHC-LKKKHALCY-- 159
Query: 350 PPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYV 409
T D ++ + G +C E +G+ + C GF+ P C+YV
Sbjct: 160 --TASCQD--MSCSKQG-----------ECLE---TIGNYTCSCYP-GFYG---PECEYV 197
Query: 410 N-CGGLTPIEDGDVALID--NRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRC 466
CG L + + + ++ + C + + + G + C GIW + P+C
Sbjct: 198 RECGELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQC 257
Query: 467 LFDWCPDPPAVSNASVT-VNGHKA---GSLASYTCENGHILSGSTSVTCTLGGAWSGVPP 522
L CP ++T ++ KA S S++CE G L G V CT G W+ P
Sbjct: 258 LAAQCPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASGVWTAPAP 317
Query: 523 SCKYVNCG-TPTIHKGSFVLINGTTT--YGSIAQFTCEPDYWLNGAEELVCNRDGKWSYD 579
CK V C +G+ ++ T YGS +F C+P Y + G + L C G WS
Sbjct: 318 VCKAVQCQHLEAPSEGTMDCVHPLTAFAYGSSCKFECQPGYRVRGLDMLRCIDSGHWSAP 377
Query: 580 IPSCELTSCPEPEVPSGGYME------AFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGE 633
+P+CE SC E P G M+ AF Y + +F C G L G + C G+
Sbjct: 378 LPTCEAISCEPLESPVHGSMDCSPSLRAFQY--DTNCSFRCAEGFMLRGADIVRCDNLGQ 435
Query: 634 WSGDSPTCEYIDCGKLPTLPYGTMELLN--GTTHLGSVIQYSCTTNYRLVGPVRRTCTEE 691
W+ +P C+ + C LP + + G SV ++C LVG C
Sbjct: 436 WTAPAPVCQALQCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLAT 495
Query: 692 FQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKY 751
W+ P C+ I C+ P+++ ++ T ++ + +T ++
Sbjct: 496 GNWNSVPPECQAIPCT-PLLSPQNGTM----------TCVQPLGSSSYKST------CQF 538
Query: 752 RCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFY--GATA 809
C++GY + G C +G+W+ + P C+ + C E G + + G+T
Sbjct: 539 ICDEGYSLSGPERLDCTRSGRWTDSPPMCEAIKCPELFAPEQGSLDCSDTRGEFNVGSTC 598
Query: 810 FYQCDENWELEGVIRRMCQENGTWSLEPPICKEI-TCPDPSAQIKA----GSGLLVVT-- 862
+ CD ++LEG C +G WS PP CK I + P P Q A G G +
Sbjct: 599 HFSCDNGFKLEGPNNVECTTSGRWSATPPTCKGIASLPTPGVQCPALTTPGQGTMYCRHH 658
Query: 863 -STLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVIS 921
T ++ C G+ L G T +C GQW P C + C + + S
Sbjct: 659 PGTFGFNTTCYFGCNAGFTLIGDSTLSCRPSGQWTAVTPACRAVKCSELHVNKPIAMNCS 718
Query: 922 N--GSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
N G+ +GS ++CL G C ++G WS P+C+
Sbjct: 719 NLWGNFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTCQ 762
Score = 89.8 bits (213), Expect = 5e-17
Identities = 52/201 (25%), Positives = 85/201 (42%), Gaps = 7/201 (3%)
Query: 778 PTCQYV-DCGN---PGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTW 833
P C+YV +CG P + N +F +F+ C + +++ G + C +G W
Sbjct: 192 PECEYVRECGELELPQHVLMNCSHPLGNFSFNSQCSFH-CTDGYQVNGPSKLECLASGIW 250
Query: 834 SLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKG 893
+ +PP C CP + L + CE G+ L G + C + G
Sbjct: 251 TNKPPQCLAAQCPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASG 310
Query: 894 QWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLF--GSSVEYYCLSQYQRVGPFLRKCLD 951
W PVC + C+ G + + T F GSS ++ C Y+ G + +C+D
Sbjct: 311 VWTAPAPVCKAVQCQHLEAPSEGTMDCVHPLTAFAYGSSCKFECQPGYRVRGLDMLRCID 370
Query: 952 DGRWSGEEPSCELATNEAVDS 972
G WS P+CE + E ++S
Sbjct: 371 SGHWSAPLPTCEAISCEPLES 391
Score = 40.7 bits (91), Expect = 0.028
Identities = 15/28 (53%), Positives = 17/28 (60%)
Query: 31 CDEGYELFGARQRECTLRGDWTLEPPFC 58
CDEGY L G + +CT G WT PP C
Sbjct: 540 CDEGYSLSGPERLDCTRSGRWTDSPPMC 567
Score = 38.7 bits (86), Expect = 0.11
Identities = 14/35 (40%), Positives = 19/35 (54%)
Query: 24 GTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
G+ + CD G++L G ECT G W+ PP C
Sbjct: 595 GSTCHFSCDNGFKLEGPNNVECTTSGRWSATPPTC 629
Score = 35.9 bits (79), Expect = 0.79
Identities = 16/58 (27%), Positives = 28/58 (48%), Gaps = 1/58 (1%)
Query: 2 CGHPAVPPNARVSIPNE-ENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
CG +P + ++ + N + + C +GY++ G + EC G WT +PP C
Sbjct: 200 CGELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQC 257
Score = 34.7 bits (76), Expect = 1.8
Identities = 18/59 (30%), Positives = 27/59 (45%), Gaps = 1/59 (1%)
Query: 1 RCGHPAVPPNARVSIPNEENIVA-GTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
+C VP ARV+ + ++ + C+EG L GA +C G+W PP C
Sbjct: 447 QCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPEC 505
Score = 34.3 bits (75), Expect = 2.4
Identities = 12/30 (40%), Positives = 16/30 (53%)
Query: 29 YECDEGYELFGARQRECTLRGDWTLEPPFC 58
+ C+EG+ L G +CT G WT P C
Sbjct: 290 FSCEEGFALVGPEVVQCTASGVWTAPAPVC 319
Score = 32.3 bits (70), Expect = 9.7
Identities = 20/62 (32%), Positives = 27/62 (43%), Gaps = 3/62 (4%)
Query: 20 NIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTNVAFRKPANQSTTVRGGAA 79
N G+I + C EG L G+ Q C G W+ P C A ++ T GGA
Sbjct: 723 NFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTC---QAGPLTIQEALTYFGGAV 779
Query: 80 AN 81
A+
Sbjct: 780 AS 781
>AL022146-7|CAI22757.1| 829|Homo sapiens selectin P (granule
membrane protein 140kDa, antigen CD62) protein.
Length = 829
Score = 235 bits (575), Expect = 6e-61
Identities = 194/764 (25%), Positives = 311/764 (40%), Gaps = 89/764 (11%)
Query: 236 SFDEARKQCQSHGGDLIHGFQGATSSFLTQELERRKAQLKTQLVWIGAQKEPGLTSRTWQ 295
S++ +RK CQ+ DL+ +L + L + WIG +K ++TW
Sbjct: 51 SWNISRKYCQNRYTDLVAIQNKNEIDYLNKVLP-----YYSSYYWIGIRKN----NKTWT 101
Query: 296 WVDGELV---SKPSWGKDQPNNYNGEQNCV---VLDGGRGWLWNDVGCNLDYLHWICQYL 349
WV + +W ++PNN ++CV + WND C L H +C
Sbjct: 102 WVGTKKALTNEAENWADNEPNNKRNNEDCVEIYIKSPSAPGKWNDEHC-LKKKHALCY-- 158
Query: 350 PPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYV 409
T D ++ + G +C E +G+ + C GF+ P C+YV
Sbjct: 159 --TASCQD--MSCSKQG-----------ECLE---TIGNYTCSCYP-GFYG---PECEYV 196
Query: 410 N-CGGLTPIEDGDVALID--NRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRC 466
CG L + + + ++ + C + + + G + C GIW + P+C
Sbjct: 197 RECGELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQC 256
Query: 467 LFDWCPDPPAVSNASVT-VNGHKA---GSLASYTCENGHILSGSTSVTCTLGGAWSGVPP 522
L CP ++T ++ KA S S++CE G L G V CT G W+ P
Sbjct: 257 LAAQCPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASGVWTAPAP 316
Query: 523 SCKYVNCG-TPTIHKGSFVLINGTTT--YGSIAQFTCEPDYWLNGAEELVCNRDGKWSYD 579
CK V C +G+ ++ T YGS +F C+P Y + G + L C G WS
Sbjct: 317 VCKAVQCQHLEAPSEGTMDCVHPLTAFAYGSSCKFECQPGYRVRGLDMLRCIDSGHWSAP 376
Query: 580 IPSCELTSCPEPEVPSGGYME------AFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGE 633
+P+CE SC E P G M+ AF Y + +F C G L G + C G+
Sbjct: 377 LPTCEAISCEPLESPVHGSMDCSPSLRAFQY--DTNCSFRCAEGFMLRGADIVRCDNLGQ 434
Query: 634 WSGDSPTCEYIDCGKLPTLPYGTMELLN--GTTHLGSVIQYSCTTNYRLVGPVRRTCTEE 691
W+ +P C+ + C LP + + G SV ++C LVG C
Sbjct: 435 WTAPAPVCQALQCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLAT 494
Query: 692 FQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKY 751
W+ P C+ I C+ P+++ ++ T ++ + +T ++
Sbjct: 495 GNWNSVPPECQAIPCT-PLLSPQNGTM----------TCVQPLGSSSYKST------CQF 537
Query: 752 RCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFY--GATA 809
C++GY + G C +G+W+ + P C+ + C E G + + G+T
Sbjct: 538 ICDEGYSLSGPERLDCTRSGRWTDSPPMCEAIKCPELFAPEQGSLDCSDTRGEFNVGSTC 597
Query: 810 FYQCDENWELEGVIRRMCQENGTWSLEPPICKEI-TCPDPSAQIKA----GSGLLVVT-- 862
+ CD ++LEG C +G WS PP CK I + P P Q A G G +
Sbjct: 598 HFSCDNGFKLEGPNNVECTTSGRWSATPPTCKGIASLPTPGVQCPALTTPGQGTMYCRHH 657
Query: 863 -STLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVIS 921
T ++ C G+ L G T +C GQW P C + C + + S
Sbjct: 658 PGTFGFNTTCYFGCNAGFTLIGDSTLSCRPSGQWTAVTPACRAVKCSELHVNKPIAMNCS 717
Query: 922 N--GSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
N G+ +GS ++CL G C ++G WS P+C+
Sbjct: 718 NLWGNFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTCQ 761
Score = 89.8 bits (213), Expect = 5e-17
Identities = 52/201 (25%), Positives = 85/201 (42%), Gaps = 7/201 (3%)
Query: 778 PTCQYV-DCGN---PGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTW 833
P C+YV +CG P + N +F +F+ C + +++ G + C +G W
Sbjct: 191 PECEYVRECGELELPQHVLMNCSHPLGNFSFNSQCSFH-CTDGYQVNGPSKLECLASGIW 249
Query: 834 SLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKG 893
+ +PP C CP + L + CE G+ L G + C + G
Sbjct: 250 TNKPPQCLAAQCPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASG 309
Query: 894 QWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLF--GSSVEYYCLSQYQRVGPFLRKCLD 951
W PVC + C+ G + + T F GSS ++ C Y+ G + +C+D
Sbjct: 310 VWTAPAPVCKAVQCQHLEAPSEGTMDCVHPLTAFAYGSSCKFECQPGYRVRGLDMLRCID 369
Query: 952 DGRWSGEEPSCELATNEAVDS 972
G WS P+CE + E ++S
Sbjct: 370 SGHWSAPLPTCEAISCEPLES 390
Score = 40.7 bits (91), Expect = 0.028
Identities = 15/28 (53%), Positives = 17/28 (60%)
Query: 31 CDEGYELFGARQRECTLRGDWTLEPPFC 58
CDEGY L G + +CT G WT PP C
Sbjct: 539 CDEGYSLSGPERLDCTRSGRWTDSPPMC 566
Score = 38.7 bits (86), Expect = 0.11
Identities = 14/35 (40%), Positives = 19/35 (54%)
Query: 24 GTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
G+ + CD G++L G ECT G W+ PP C
Sbjct: 594 GSTCHFSCDNGFKLEGPNNVECTTSGRWSATPPTC 628
Score = 35.9 bits (79), Expect = 0.79
Identities = 16/58 (27%), Positives = 28/58 (48%), Gaps = 1/58 (1%)
Query: 2 CGHPAVPPNARVSIPNE-ENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
CG +P + ++ + N + + C +GY++ G + EC G WT +PP C
Sbjct: 199 CGELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQC 256
Score = 34.7 bits (76), Expect = 1.8
Identities = 18/59 (30%), Positives = 27/59 (45%), Gaps = 1/59 (1%)
Query: 1 RCGHPAVPPNARVSIPNEENIVA-GTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
+C VP ARV+ + ++ + C+EG L GA +C G+W PP C
Sbjct: 446 QCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPEC 504
Score = 34.3 bits (75), Expect = 2.4
Identities = 12/30 (40%), Positives = 16/30 (53%)
Query: 29 YECDEGYELFGARQRECTLRGDWTLEPPFC 58
+ C+EG+ L G +CT G WT P C
Sbjct: 289 FSCEEGFALVGPEVVQCTASGVWTAPAPVC 318
Score = 32.3 bits (70), Expect = 9.7
Identities = 20/62 (32%), Positives = 27/62 (43%), Gaps = 3/62 (4%)
Query: 20 NIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTNVAFRKPANQSTTVRGGAA 79
N G+I + C EG L G+ Q C G W+ P C A ++ T GGA
Sbjct: 722 NFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTC---QAGPLTIQEALTYFGGAV 778
Query: 80 AN 81
A+
Sbjct: 779 AS 780
>AL022146-2|CAI22753.1| 830|Homo sapiens selectin P (granule
membrane protein 140kDa, antigen CD62) protein.
Length = 830
Score = 235 bits (575), Expect = 6e-61
Identities = 194/764 (25%), Positives = 311/764 (40%), Gaps = 89/764 (11%)
Query: 236 SFDEARKQCQSHGGDLIHGFQGATSSFLTQELERRKAQLKTQLVWIGAQKEPGLTSRTWQ 295
S++ +RK CQ+ DL+ +L + L + WIG +K ++TW
Sbjct: 52 SWNISRKYCQNRYTDLVAIQNKNEIDYLNKVLP-----YYSSYYWIGIRKN----NKTWT 102
Query: 296 WVDGELV---SKPSWGKDQPNNYNGEQNCV---VLDGGRGWLWNDVGCNLDYLHWICQYL 349
WV + +W ++PNN ++CV + WND C L H +C
Sbjct: 103 WVGTKKALTNEAENWADNEPNNKRNNEDCVEIYIKSPSAPGKWNDEHC-LKKKHALCY-- 159
Query: 350 PPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYV 409
T D ++ + G +C E +G+ + C GF+ P C+YV
Sbjct: 160 --TASCQD--MSCSKQG-----------ECLE---TIGNYTCSCYP-GFYG---PECEYV 197
Query: 410 N-CGGLTPIEDGDVALID--NRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRC 466
CG L + + + ++ + C + + + G + C GIW + P+C
Sbjct: 198 RECGELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQC 257
Query: 467 LFDWCPDPPAVSNASVT-VNGHKA---GSLASYTCENGHILSGSTSVTCTLGGAWSGVPP 522
L CP ++T ++ KA S S++CE G L G V CT G W+ P
Sbjct: 258 LAAQCPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASGVWTAPAP 317
Query: 523 SCKYVNCG-TPTIHKGSFVLINGTTT--YGSIAQFTCEPDYWLNGAEELVCNRDGKWSYD 579
CK V C +G+ ++ T YGS +F C+P Y + G + L C G WS
Sbjct: 318 VCKAVQCQHLEAPSEGTMDCVHPLTAFAYGSSCKFECQPGYRVRGLDMLRCIDSGHWSAP 377
Query: 580 IPSCELTSCPEPEVPSGGYME------AFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGE 633
+P+CE SC E P G M+ AF Y + +F C G L G + C G+
Sbjct: 378 LPTCEAISCEPLESPVHGSMDCSPSLRAFQY--DTNCSFRCAEGFMLRGADIVRCDNLGQ 435
Query: 634 WSGDSPTCEYIDCGKLPTLPYGTMELLN--GTTHLGSVIQYSCTTNYRLVGPVRRTCTEE 691
W+ +P C+ + C LP + + G SV ++C LVG C
Sbjct: 436 WTAPAPVCQALQCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLAT 495
Query: 692 FQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKY 751
W+ P C+ I C+ P+++ ++ T ++ + +T ++
Sbjct: 496 GNWNSVPPECQAIPCT-PLLSPQNGTM----------TCVQPLGSSSYKST------CQF 538
Query: 752 RCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFY--GATA 809
C++GY + G C +G+W+ + P C+ + C E G + + G+T
Sbjct: 539 ICDEGYSLSGPERLDCTRSGRWTDSPPMCEAIKCPELFAPEQGSLDCSDTRGEFNVGSTC 598
Query: 810 FYQCDENWELEGVIRRMCQENGTWSLEPPICKEI-TCPDPSAQIKA----GSGLLVVT-- 862
+ CD ++LEG C +G WS PP CK I + P P Q A G G +
Sbjct: 599 HFSCDNGFKLEGPNNVECTTSGRWSATPPTCKGIASLPTPGVQCPALTTPGQGTMYCRHH 658
Query: 863 -STLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVIS 921
T ++ C G+ L G T +C GQW P C + C + + S
Sbjct: 659 PGTFGFNTTCYFGCNAGFTLIGDSTLSCRPSGQWTAVTPACRAVKCSELHVNKPIAMNCS 718
Query: 922 N--GSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
N G+ +GS ++CL G C ++G WS P+C+
Sbjct: 719 NLWGNFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTCQ 762
Score = 89.8 bits (213), Expect = 5e-17
Identities = 52/201 (25%), Positives = 85/201 (42%), Gaps = 7/201 (3%)
Query: 778 PTCQYV-DCGN---PGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTW 833
P C+YV +CG P + N +F +F+ C + +++ G + C +G W
Sbjct: 192 PECEYVRECGELELPQHVLMNCSHPLGNFSFNSQCSFH-CTDGYQVNGPSKLECLASGIW 250
Query: 834 SLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKG 893
+ +PP C CP + L + CE G+ L G + C + G
Sbjct: 251 TNKPPQCLAAQCPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASG 310
Query: 894 QWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLF--GSSVEYYCLSQYQRVGPFLRKCLD 951
W PVC + C+ G + + T F GSS ++ C Y+ G + +C+D
Sbjct: 311 VWTAPAPVCKAVQCQHLEAPSEGTMDCVHPLTAFAYGSSCKFECQPGYRVRGLDMLRCID 370
Query: 952 DGRWSGEEPSCELATNEAVDS 972
G WS P+CE + E ++S
Sbjct: 371 SGHWSAPLPTCEAISCEPLES 391
Score = 40.7 bits (91), Expect = 0.028
Identities = 15/28 (53%), Positives = 17/28 (60%)
Query: 31 CDEGYELFGARQRECTLRGDWTLEPPFC 58
CDEGY L G + +CT G WT PP C
Sbjct: 540 CDEGYSLSGPERLDCTRSGRWTDSPPMC 567
Score = 38.7 bits (86), Expect = 0.11
Identities = 14/35 (40%), Positives = 19/35 (54%)
Query: 24 GTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
G+ + CD G++L G ECT G W+ PP C
Sbjct: 595 GSTCHFSCDNGFKLEGPNNVECTTSGRWSATPPTC 629
Score = 35.9 bits (79), Expect = 0.79
Identities = 16/58 (27%), Positives = 28/58 (48%), Gaps = 1/58 (1%)
Query: 2 CGHPAVPPNARVSIPNE-ENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
CG +P + ++ + N + + C +GY++ G + EC G WT +PP C
Sbjct: 200 CGELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQC 257
Score = 34.7 bits (76), Expect = 1.8
Identities = 18/59 (30%), Positives = 27/59 (45%), Gaps = 1/59 (1%)
Query: 1 RCGHPAVPPNARVSIPNEENIVA-GTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
+C VP ARV+ + ++ + C+EG L GA +C G+W PP C
Sbjct: 447 QCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPEC 505
Score = 34.3 bits (75), Expect = 2.4
Identities = 12/30 (40%), Positives = 16/30 (53%)
Query: 29 YECDEGYELFGARQRECTLRGDWTLEPPFC 58
+ C+EG+ L G +CT G WT P C
Sbjct: 290 FSCEEGFALVGPEVVQCTASGVWTAPAPVC 319
Score = 32.3 bits (70), Expect = 9.7
Identities = 20/62 (32%), Positives = 27/62 (43%), Gaps = 3/62 (4%)
Query: 20 NIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTNVAFRKPANQSTTVRGGAA 79
N G+I + C EG L G+ Q C G W+ P C A ++ T GGA
Sbjct: 723 NFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTC---QAGPLTIQEALTYFGGAV 779
Query: 80 AN 81
A+
Sbjct: 780 AS 781
>BC068533-1|AAH68533.1| 829|Homo sapiens selectin P (granule
membrane protein 140kDa, antigen CD62) protein.
Length = 829
Score = 235 bits (574), Expect = 8e-61
Identities = 194/764 (25%), Positives = 311/764 (40%), Gaps = 89/764 (11%)
Query: 236 SFDEARKQCQSHGGDLIHGFQGATSSFLTQELERRKAQLKTQLVWIGAQKEPGLTSRTWQ 295
S++ +RK CQ+ DL+ +L + L + WIG +K ++TW
Sbjct: 52 SWNISRKYCQNRYTDLVAIQNKNEIDYLNKVLP-----YYSSYYWIGIRKN----NKTWT 102
Query: 296 WVDGELV---SKPSWGKDQPNNYNGEQNCV---VLDGGRGWLWNDVGCNLDYLHWICQYL 349
WV + +W ++PNN ++CV + WND C L H +C
Sbjct: 103 WVGTKKALTNEAENWADNEPNNKRNNEDCVEIYIKSPSAPGKWNDEHC-LKKKHALCY-- 159
Query: 350 PPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYV 409
T D ++ + G +C E +G+ + C GF+ P C+YV
Sbjct: 160 --TASCQD--MSCSKQG-----------ECLE---TIGNYTCSCYP-GFYG---PECEYV 197
Query: 410 N-CGGLTPIEDGDVALID--NRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRC 466
CG L + + + ++ + C + + + G + C GIW + P+C
Sbjct: 198 RECGELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQC 257
Query: 467 LFDWCPDPPAVSNASVT-VNGHKA---GSLASYTCENGHILSGSTSVTCTLGGAWSGVPP 522
L CP ++T ++ KA S S++CE G L G V CT G W+ P
Sbjct: 258 LAAQCPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASGVWTAPAP 317
Query: 523 SCKYVNCG-TPTIHKGSFVLINGTTT--YGSIAQFTCEPDYWLNGAEELVCNRDGKWSYD 579
CK V C +G+ ++ T YGS +F C+P Y + G + L C G WS
Sbjct: 318 VCKAVQCQHLEAPSEGTMDCVHPLTAFAYGSSCKFECQPGYRVRGLDMLRCIDSGHWSAP 377
Query: 580 IPSCELTSCPEPEVPSGGYME------AFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGE 633
+P+CE SC E P G M+ AF Y + +F C G L G + C G+
Sbjct: 378 LPTCEAISCEPLESPVHGSMDCSPSLRAFQY--DTNCSFRCAEGFMLRGADIVRCDNLGQ 435
Query: 634 WSGDSPTCEYIDCGKLPTLPYGTMELLN--GTTHLGSVIQYSCTTNYRLVGPVRRTCTEE 691
W+ +P C+ + C LP + + G SV ++C LVG C
Sbjct: 436 WTAPAPVCQALQCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLAT 495
Query: 692 FQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKY 751
W+ P C+ I C+ P+++ ++ T +R + +T ++
Sbjct: 496 GNWNSVPPECQAIPCT-PLLSPQNGTM----------TCVRPLGSSSYKST------CQF 538
Query: 752 RCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFY--GATA 809
C++GY + G C +G+W+ + P C+ + C E G + + G+T
Sbjct: 539 ICDEGYSLSGPERLDCTRSGRWTDSPPMCEAIKCPELFAPEQGSLDCSDTRGEFNVGSTC 598
Query: 810 FYQCDENWELEGVIRRMCQENGTWSLEPPICKEI-TCPDPSAQIKA----GSGLLVVT-- 862
+ C+ ++LEG C +G WS PP CK I + P P Q A G G +
Sbjct: 599 HFSCNNGFKLEGPNNVECTTSGRWSATPPTCKGIASLPTPGVQCPALTTPGQGTMYCRHH 658
Query: 863 -STLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVIS 921
T ++ C G+ L G T +C GQW P C + C + + S
Sbjct: 659 PGTFGFNTTCYFGCNAGFTLIGDSTLSCRPSGQWTAVTPACRAVKCSELHVNKPIAMNCS 718
Query: 922 N--GSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
N G+ +GS ++CL G C ++G WS P+C+
Sbjct: 719 NLWGNFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTCQ 762
Score = 89.8 bits (213), Expect = 5e-17
Identities = 52/201 (25%), Positives = 85/201 (42%), Gaps = 7/201 (3%)
Query: 778 PTCQYV-DCGN---PGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTW 833
P C+YV +CG P + N +F +F+ C + +++ G + C +G W
Sbjct: 192 PECEYVRECGELELPQHVLMNCSHPLGNFSFNSQCSFH-CTDGYQVNGPSKLECLASGIW 250
Query: 834 SLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKG 893
+ +PP C CP + L + CE G+ L G + C + G
Sbjct: 251 TNKPPQCLAAQCPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASG 310
Query: 894 QWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLF--GSSVEYYCLSQYQRVGPFLRKCLD 951
W PVC + C+ G + + T F GSS ++ C Y+ G + +C+D
Sbjct: 311 VWTAPAPVCKAVQCQHLEAPSEGTMDCVHPLTAFAYGSSCKFECQPGYRVRGLDMLRCID 370
Query: 952 DGRWSGEEPSCELATNEAVDS 972
G WS P+CE + E ++S
Sbjct: 371 SGHWSAPLPTCEAISCEPLES 391
Score = 40.7 bits (91), Expect = 0.028
Identities = 15/28 (53%), Positives = 17/28 (60%)
Query: 31 CDEGYELFGARQRECTLRGDWTLEPPFC 58
CDEGY L G + +CT G WT PP C
Sbjct: 540 CDEGYSLSGPERLDCTRSGRWTDSPPMC 567
Score = 36.7 bits (81), Expect = 0.45
Identities = 13/35 (37%), Positives = 19/35 (54%)
Query: 24 GTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
G+ + C+ G++L G ECT G W+ PP C
Sbjct: 595 GSTCHFSCNNGFKLEGPNNVECTTSGRWSATPPTC 629
Score = 35.9 bits (79), Expect = 0.79
Identities = 16/58 (27%), Positives = 28/58 (48%), Gaps = 1/58 (1%)
Query: 2 CGHPAVPPNARVSIPNE-ENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
CG +P + ++ + N + + C +GY++ G + EC G WT +PP C
Sbjct: 200 CGELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQC 257
Score = 34.7 bits (76), Expect = 1.8
Identities = 18/59 (30%), Positives = 27/59 (45%), Gaps = 1/59 (1%)
Query: 1 RCGHPAVPPNARVSIPNEENIVA-GTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
+C VP ARV+ + ++ + C+EG L GA +C G+W PP C
Sbjct: 447 QCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPEC 505
Score = 34.3 bits (75), Expect = 2.4
Identities = 12/30 (40%), Positives = 16/30 (53%)
Query: 29 YECDEGYELFGARQRECTLRGDWTLEPPFC 58
+ C+EG+ L G +CT G WT P C
Sbjct: 290 FSCEEGFALVGPEVVQCTASGVWTAPAPVC 319
Score = 32.7 bits (71), Expect = 7.4
Identities = 19/62 (30%), Positives = 28/62 (45%), Gaps = 4/62 (6%)
Query: 20 NIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTNVAFRKPANQSTTVRGGAA 79
N G+I + C EG L G+ Q C G W+ P C + + ++ T GGA
Sbjct: 723 NFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTCQGPLTIQ----EALTYFGGAV 778
Query: 80 AN 81
A+
Sbjct: 779 AS 780
>Y00816-1|CAA68755.1| 2039|Homo sapiens protein ( Human mRNA for
complement receptor type 1 (CR1, C3b/C4b receptor,
CD35). ).
Length = 2039
Score = 234 bits (573), Expect = 1e-60
Identities = 194/665 (29%), Positives = 275/665 (41%), Gaps = 78/665 (11%)
Query: 352 TCGSPDKLLNTTI-LGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDG---FWSGAPPSCK 407
+C +P +N + + D VGSRI Y C GH L+G S C G WS PP C+
Sbjct: 553 SCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQ 612
Query: 408 YVNCGGLTPIEDGDVALIDNRTTH-GARALYSC------RENFTLVGNPERTC--GDE-- 456
+ CG I +GD + H G+ Y C R+ F LVG P C D+
Sbjct: 613 RIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQV 672
Query: 457 GIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGSL---ASYTCENGHILSGSTSVTCTL 513
GIW G AP+C+ PP V N + + SL + C+ G ++ G V C
Sbjct: 673 GIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQA 732
Query: 514 GGAWSGVPPSCKYVNCGTP--TIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCN 571
W PSC V C P +H + G ++CEP Y L GA + C
Sbjct: 733 LNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCT 791
Query: 572 RDGKWSYDIPSCELTSCPE--PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQ 629
G WS P+CE+ SC + ++ +G + + + + ++F C+ G +L G C
Sbjct: 792 PQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCV 851
Query: 630 QDGE---WSGDSPTCEYIDCGKLPTLPYG--TMELLNGTTHLGSVIQYSCT------TNY 678
G W+ P CE I C P +P G T + L G + Y+C T++
Sbjct: 852 LAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLE-VFPFGKAVNYTCDPHPDRGTSF 910
Query: 679 RLVGPVRRTCTEEFQ----WSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTS 734
L+G CT + Q WS +PRC + G+ ++ H L
Sbjct: 911 DLIGESTIRCTSDPQGNGVWSSPAPRC----------------GILGHCQAPDHFLFAKL 954
Query: 735 DNRDVGNTYRIGALVKYRCEKGYKVIGESLS-TCEDNGQWSGTTPTCQYVDCGNPGRIEN 793
+ + + IG +KY C Y G S TC DN WS C+ C P N
Sbjct: 955 KTQTNASDFPIGTSLKYECRPEY--YGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVN 1012
Query: 794 GKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGT---WSLEPPICKEITCPDPSA 850
G V + ++ G+ Y C L G C +G WS +PPIC+ I C P
Sbjct: 1013 GMVHVITDIQV-GSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPCGLPPT 1071
Query: 851 QIKAGSGLLVVTSTLSIGGEAHYQCERG------YNLKGHQTRTCISK----GQWNGTVP 900
I G + G Y+C G + L G + C S G W+G P
Sbjct: 1072 -IANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAP 1130
Query: 901 VC-IPIDCRSPGNIENGKIVISNGSTLFGSS--VEYYCLSQYQRVGPFLRKCLDDGRWSG 957
C IP C +P N+ENG I++S+ +LF + VE+ C + GP KC +W
Sbjct: 1131 QCIIPNKC-TPPNVENG-ILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEP 1188
Query: 958 EEPSC 962
E PSC
Sbjct: 1189 ELPSC 1193
Score = 227 bits (555), Expect = 2e-58
Identities = 187/662 (28%), Positives = 274/662 (41%), Gaps = 69/662 (10%)
Query: 352 TCGSPDKLLNTTI-LGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDG---FWSGAPPSCK 407
+C +P +N + + D VGSRI Y C GH L+G S C G WS PP C+
Sbjct: 1003 SCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQ 1062
Query: 408 YVNCGGLTPIEDGDVALIDNRTTH-GARALYSC------RENFTLVGNPERTC--GDE-- 456
+ CG I +GD + H G+ Y C R+ F LVG P C D+
Sbjct: 1063 RIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQV 1122
Query: 457 GIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGSL---ASYTCENGHILSGSTSVTCTL 513
GIW G AP+C+ PP V N + + SL + C+ G ++ G V C
Sbjct: 1123 GIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQA 1182
Query: 514 GGAWSGVPPSCKYVNCGTPTIHKGSFVLINGTT-TYGSIAQFTCEPDYWLNGAEELVCNR 572
W PSC V P I G + + G ++CEP Y L GA L C
Sbjct: 1183 LNKWEPELPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTP 1242
Query: 573 DGKWSYDIPSCELTSCPE--PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQ 630
G WS + P C + SC + ++P G + + + + ++F C+ G +L G C
Sbjct: 1243 QGDWSPEAPRCAVKSCDDFLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCVL 1302
Query: 631 DGE---WSGDSPTCEYIDCGKLPTLPYGT-MELLNGTTHLGSVIQYSCTTN------YRL 680
G W+ P CE+I C P + G +G G I Y+C + + L
Sbjct: 1303 VGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNL 1362
Query: 681 VGPVRRTCTEEFQ----WSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDN 736
+G CT + WS +PRCE ++ ++ T I +D
Sbjct: 1363 IGESTIRCTSDPHGNGVWSSPAPRCE--------LSVRAGHCKTPEQFPFASPTIPINDF 1414
Query: 737 RDVGNTYRIGALVKYRCEKGYKVIGESLS-TCEDNGQWSGTTPTCQYVDCGNPGRIENGK 795
+ +G + Y C GY G+ S +C +N WS C+ CG P NG
Sbjct: 1415 E-----FPVGTSLNYECRPGY--FGKMFSISCLENLVWSSVEDNCRRKSCGPPPEPFNGM 1467
Query: 796 VTLPSNATFYGATAFYQCDENWELEGVIRRMCQENG---TWSLEPPICKEITCPDPSAQI 852
V + ++ T +G+T Y C+E + L G C +G TW + PIC+ I+C +P I
Sbjct: 1468 VHINTD-TQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISC-EPPPTI 1525
Query: 853 KAGSGLLVVTSTLSIGGEAHYQCERG------YNLKGHQTRTCISK----GQWNGTVPVC 902
G ++ G YQC G + L G ++ C SK G W+ P C
Sbjct: 1526 SNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRC 1585
Query: 903 IPID-CRSPGNIENGKIVISNGSTL-FGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEP 960
I + C +P +EN V N S + + C + VG +C +GRW + P
Sbjct: 1586 ISTNKCTAP-EVENAIRVPGNRSFFSLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLP 1644
Query: 961 SC 962
C
Sbjct: 1645 HC 1646
Score = 224 bits (547), Expect = 2e-57
Identities = 175/645 (27%), Positives = 261/645 (40%), Gaps = 74/645 (11%)
Query: 368 DYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDN 427
++ +G+ + Y+C G+ S C K+ W+GA C+ +C +G V +I
Sbjct: 62 EFPIGTYLNYECRPGYSGR-PFSIICLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKG 120
Query: 428 RTTHGARALYSCRENFTLVGNPERTC---GDEGIWDGEAPRCLFDWCPDPPAVSNA---S 481
G++ YSC + + L+G+ TC GD IWD E P C C PP ++N S
Sbjct: 121 -IQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTITNGDFIS 179
Query: 482 VTVNGHKAGSLASYTCENG------HILSGSTSVTCTLG----GAWSGVPPSCKYVN-CG 530
GS+ +Y C G L G S+ CT G WSG P C N C
Sbjct: 180 TNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCT 239
Query: 531 TPTIHKGSFVLINGTT-TYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCP 589
P + G V N + + + +F C+P + + G + C KW ++PSC P
Sbjct: 240 PPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQP 299
Query: 590 EPEV--PSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCG 647
P+V + ++ + + CE G+ L G ++ C G+WS +PTCE C
Sbjct: 300 PPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCD 359
Query: 648 KLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCT---EEFQWSDSSPRCEEI 704
L LG+ + + C ++L G C E W+ S P CE+I
Sbjct: 360 DFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQI 419
Query: 705 RCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCE------KGYK 758
C P V N R G L + G V Y C+ +
Sbjct: 420 FCPSP--------PVIPNGRHTGKPL----------EVFPFGKAVNYTCDPHPDRGTSFD 461
Query: 759 VIGESLSTC----EDNGQWSGTTPTCQYV-DCGNPGRIENGKVTLPSNATFY--GATAFY 811
+IGES C + NG WS P C + C P K+ +NA+ + G + Y
Sbjct: 462 LIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKY 521
Query: 812 QCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEA 871
+C + C +N WS +CK +C P + +G++ V + + +G
Sbjct: 522 ECRPEY-YGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPV---NGMVHVITDIQVGSRI 577
Query: 872 HYQCERGYNLKGHQTRTCISKG---QWNGTVPVCIPIDCRSPGNIENGKIVISNGSTL-F 927
+Y C G+ L GH + CI G W+ P+C I C P I NG + +N +
Sbjct: 578 NYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHY 637
Query: 928 GSSVEYYC------LSQYQRVGPFLRKCL--DD--GRWSGEEPSC 962
GS V Y C ++ VG C DD G WSG P C
Sbjct: 638 GSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQC 682
Score = 221 bits (541), Expect = 8e-57
Identities = 188/665 (28%), Positives = 271/665 (40%), Gaps = 78/665 (11%)
Query: 352 TCGSPDKLLNTTI-LGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDG---FWSGAPPSCK 407
+C +P +N + + GS+I Y C +G+ L+G S C G W P C
Sbjct: 103 SCRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICD 162
Query: 408 YVNCGGLTPIEDGDVALIDNRTTH-GARALYSC------RENFTLVGNPERTC--GDE-- 456
+ CG I +GD + H G+ Y C R+ F LVG P C D+
Sbjct: 163 RIPCGLPPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQV 222
Query: 457 GIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGSL---ASYTCENGHILSGSTSVTCTL 513
GIW G AP+C+ PP V N + + SL + C+ G ++ G V C
Sbjct: 223 GIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQA 282
Query: 514 GGAWSGVPPSCKYVNCGTP--TIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCN 571
W PSC V C P +H + G ++CEP Y L GA + C
Sbjct: 283 LNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCT 341
Query: 572 RDGKWSYDIPSCELTSCPE--PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQ 629
G WS P+CE+ SC + ++ +G + + + + ++F C+ G +L G C
Sbjct: 342 PQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCV 401
Query: 630 QDGE---WSGDSPTCEYIDCGKLPTLPYG--TMELLNGTTHLGSVIQYSCT------TNY 678
G W+ P CE I C P +P G T + L G + Y+C T++
Sbjct: 402 LAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLE-VFPFGKAVNYTCDPHPDRGTSF 460
Query: 679 RLVGPVRRTCTEEFQ----WSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTS 734
L+G CT + Q WS +PRC + G+ ++ H L
Sbjct: 461 DLIGESTIRCTSDPQGNGVWSSPAPRC----------------GILGHCQAPDHFLFAKL 504
Query: 735 DNRDVGNTYRIGALVKYRCEKGYKVIGESLS-TCEDNGQWSGTTPTCQYVDCGNPGRIEN 793
+ + + IG +KY C Y G S TC DN WS C+ C P N
Sbjct: 505 KTQTNASDFPIGTSLKYECRPEY--YGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVN 562
Query: 794 GKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGT---WSLEPPICKEITCPDPSA 850
G V + ++ G+ Y C L G C +G WS +PPIC+ I C P
Sbjct: 563 GMVHVITDIQV-GSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPT 621
Query: 851 QIKAGSGLLVVTSTLSIGGEAHYQCERG------YNLKGHQTRTCISK----GQWNGTVP 900
I G + G Y+C G + L G + C S G W+G P
Sbjct: 622 -IANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAP 680
Query: 901 VC-IPIDCRSPGNIENGKIVISNGSTLFGSS--VEYYCLSQYQRVGPFLRKCLDDGRWSG 957
C IP C +P N+ENG I++S+ +LF + VE+ C + GP KC +W
Sbjct: 681 QCIIPNKC-TPPNVENG-ILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEP 738
Query: 958 EEPSC 962
E PSC
Sbjct: 739 ELPSC 743
Score = 205 bits (501), Expect = 6e-52
Identities = 178/668 (26%), Positives = 269/668 (40%), Gaps = 72/668 (10%)
Query: 353 CGSPDKLL----NTTILGNDYDVGSRIVYKC-PEGHMLLGDKSRHCKKDGFWSGAPPSCK 407
C +PD L T +D+ +G+ + Y+C PE + S C + WS CK
Sbjct: 943 CQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGR--PFSITCLDNLVWSSPKDVCK 1000
Query: 408 YVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTC---GDEGIWDGEAP 464
+C +G V +I + G+R YSC L+G+ C G+ W + P
Sbjct: 1001 RKSCKTPPDPVNGMVHVITDIQV-GSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPP 1059
Query: 465 RCLFDWCPDPPAVSNAS-VTVNGHKA--GSLASYTCENGHI------LSGSTSVTCTLG- 514
C C PP ++N ++ N GS+ +Y C G L G S+ CT
Sbjct: 1060 ICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSND 1119
Query: 515 ---GAWSGVPPSCKYVN-CGTPTIHKGSFVLINGTT-TYGSIAQFTCEPDYWLNGAEELV 569
G WSG P C N C P + G V N + + + +F C+P + + G +
Sbjct: 1120 DQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVK 1179
Query: 570 CNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAF--DYYVHSTINFHCEAGHKLIGEPNLV 627
C KW ++PSC P PE+ G + + ++ + + CE G+ L G +L
Sbjct: 1180 CQALNKWEPELPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLH 1239
Query: 628 CQQDGEWSGDSPTCEYIDCGK-LPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRR 686
C G+WS ++P C C L LP+G + L LG+ + + C +RL G
Sbjct: 1240 CTPQGDWSPEAPRCAVKSCDDFLGQLPHGRV-LFPLNLQLGAKVSFVCDEGFRLKGSSVS 1298
Query: 687 TCT---EEFQWSDSSPRCEEIRCSDP-IVAEKSIVSVTGNDRSHGHTLIRTSD-NRDVGN 741
C W++S P CE I C +P + D +G + T D + D G
Sbjct: 1299 HCVLVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGM 1358
Query: 742 TYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYV----DCGNPGRIENGKVT 797
T+ + RC S NG WS P C+ C P + T
Sbjct: 1359 TFNLIGESTIRCT----------SDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPT 1408
Query: 798 LPSNATFY--GATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAG 855
+P N + G + Y+C + + C EN WS C+ +C P
Sbjct: 1409 IPINDFEFPVGTSLNYECRPGY-FGKMFSISCLENLVWSSVEDNCRRKSCGPPPEPF--- 1464
Query: 856 SGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQ---WNGTVPVCIPIDCRSPGN 912
+G++ + + G +Y C G+ L G + TC+ G W+ P+C I C P
Sbjct: 1465 NGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPT 1524
Query: 913 IENGKIVISNGSTLF--GSSVEYYCLS------QYQRVGPFLRKCL--DD--GRWSGEEP 960
I NG SN T F G+ V Y C + ++ VG C DD G WS P
Sbjct: 1525 ISNGDF-YSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPP 1583
Query: 961 SCELATNE 968
C ++TN+
Sbjct: 1584 RC-ISTNK 1590
Score = 200 bits (487), Expect = 3e-50
Identities = 170/650 (26%), Positives = 256/650 (39%), Gaps = 79/650 (12%)
Query: 371 VGSRIVYKCPEGHMLLGDKSRHCKKDGF---WSGAPPSCKYVNCGGLTPIEDG-DVALID 426
+G+++ + C EG L G HC G W+ + P C+++ C I +G
Sbjct: 1278 LGAKVSFVCDEGFRLKGSSVSHCVLVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPS 1337
Query: 427 NRTTHGARALYSCREN------FTLVGNPERTCGDE----GIWDGEAPRCLFD----WCP 472
+G Y+C + F L+G C + G+W APRC C
Sbjct: 1338 GDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTSDPHGNGVWSSPAPRCELSVRAGHCK 1397
Query: 473 DPPAVSNASVTV--NGHK--AGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVN 528
P AS T+ N + G+ +Y C G+ S++C WS V +C+ +
Sbjct: 1398 TPEQFPFASPTIPINDFEFPVGTSLNYECRPGYF-GKMFSISCLENLVWSSVEDNCRRKS 1456
Query: 529 CGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGK---WSYDIPSCEL 585
CG P V IN T +GS ++C + L G+ C G W P CE+
Sbjct: 1457 CGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEI 1516
Query: 586 TSC-PEPEVPSGGYM--EAFDYYVHSTINFHCEAG------HKLIGEPNLVC----QQDG 632
SC P P + +G + ++ + + + C G +L+GE ++ C Q G
Sbjct: 1517 ISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVG 1576
Query: 633 EWSGDSPTCEYIDCGKLPTLPYGTMELLNGT-THLGSVIQYSCTTNYRLVGPVRRTCTEE 691
WS P C + P + N + L +I++ C + +VG C
Sbjct: 1577 VWSSPPPRCISTNKCTAPEVENAIRVPGNRSFFSLTEIIRFRCQPGFVMVGSHTVQCQTN 1636
Query: 692 FQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKY 751
+W P C + C P + HG + DN + G V Y
Sbjct: 1637 GRWGPKLPHCSRV-CQPP------------PEILHGEHTLSHQDN------FSPGQEVFY 1677
Query: 752 RCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGN-PGRIENGKVTLPSNATFYGATAF 810
CE Y + G + C G WS P C C + G++ +G+V LP N GA
Sbjct: 1678 SCEPSYDLRGAASLHCTPQGDWSPEAPRCTVKSCDDFLGQLPHGRVLLPLNLQL-GAKVS 1736
Query: 811 YQCDENWELEGVIRRMCQENG---TWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSI 867
+ CDE + L+G C G W+ P+C++I CP+P A I G +
Sbjct: 1737 FVCDEGFRLKGRSASHCVLAGMKALWNSSVPVCEQIFCPNPPA-ILNGRHTGTPFGDIPY 1795
Query: 868 GGEAHYQC----ERG--YNLKGHQTRTCIS----KGQWNGTVPVC---IPIDCRSPGNIE 914
G E Y C +RG +NL G + C S G W+ P C +P C P I+
Sbjct: 1796 GKEISYACDTHPDRGMTFNLIGESSIRCTSDPQGNGVWSSPAPRCELSVPAACPHPPKIQ 1855
Query: 915 NGKIVISNGST-LFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
NG + + S L G ++ Y C Y VG C D G WS + C+
Sbjct: 1856 NGHYIGGHVSLYLPGMTISYTCDPGYLLVGKGFIFCTDQGIWSQLDHYCK 1905
Score = 196 bits (479), Expect = 3e-49
Identities = 181/674 (26%), Positives = 263/674 (39%), Gaps = 82/674 (12%)
Query: 353 CGSPDKLLNTTILGNDYDV---GSRIVYKC---PE---GHMLLGDKSRHCKKD----GFW 399
C SP + N G +V G + Y C P+ L+G+ + C D G W
Sbjct: 871 CPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVW 930
Query: 400 SGAPPSCKYV-NCGGLTPIEDGDVALIDNRTTH--GARALYSCRENFTLVGNP-ERTCGD 455
S P C + +C + N + G Y CR + G P TC D
Sbjct: 931 SSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEY--YGRPFSITCLD 988
Query: 456 EGIWDGEAPRCLFDWCPDPPAVSNASV-TVNGHKAGSLASYTCENGHILSGSTSVTCTLG 514
+W C C PP N V + + GS +Y+C GH L G +S C L
Sbjct: 989 NLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILS 1048
Query: 515 GA---WSGVPPSCKYVNCGTP-TIHKGSFVLINGTTT-YGSIAQFTCEPD------YWLN 563
G WS PP C+ + CG P TI G F+ N YGS+ + C + L
Sbjct: 1049 GNTAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELV 1108
Query: 564 GAEELVC--NRD--GKWSYDIPSCELTS-CPEPEVPSGGYMEAFD--YYVHSTINFHCEA 616
G + C N D G WS P C + + C P V +G + + ++ + F C+
Sbjct: 1109 GEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQP 1168
Query: 617 GHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHL-GSVIQYSCT 675
G + G + CQ +W + P+C + C P + +G + G + YSC
Sbjct: 1169 GFVMKGPRRVKCQALNKWEPELPSCSRV-CQPPPEILHGEHTPSHQDNFSPGQEVFYSCE 1227
Query: 676 TNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSD 735
Y L G CT + WS +PRC C D + HG L +
Sbjct: 1228 PGYDLRGAASLHCTPQGDWSPEAPRCAVKSCDDFL-----------GQLPHGRVLFPLN- 1275
Query: 736 NRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTCQYVDCGNPGRIE 792
++GA V + C++G+++ G S+S C G W+ + P C+++ C NP I
Sbjct: 1276 -------LQLGAKVSFVCDEGFRLKGSSVSHCVLVGMRSLWNNSVPVCEHIFCPNPPAIL 1328
Query: 793 NGKVT-LPSNATFYGATAFYQCDEN------WELEGVIRRMCQE----NGTWSLEPPICK 841
NG+ T PS YG Y CD + + L G C NG WS P C+
Sbjct: 1329 NGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTSDPHGNGVWSSPAPRCE 1388
Query: 842 EIT----CPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNG 897
C P A + + +G +Y+C GY K +C+ W+
Sbjct: 1389 LSVRAGHCKTPEQFPFASPTIPINDFEFPVGTSLNYECRPGYFGKMFSI-SCLENLVWSS 1447
Query: 898 TVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGR--- 954
C C P NG + I N T FGS+V Y C ++ +G CL G
Sbjct: 1448 VEDNCRRKSCGPPPEPFNGMVHI-NTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVT 1506
Query: 955 WSGEEPSCELATNE 968
W + P CE+ + E
Sbjct: 1507 WDKKAPICEIISCE 1520
Score = 196 bits (478), Expect = 4e-49
Identities = 175/676 (25%), Positives = 275/676 (40%), Gaps = 86/676 (12%)
Query: 345 ICQYLPPTCGSPDKLLNTTILGND---YDVGSRIVYKCPEGH------MLLGDKSRHCKK 395
IC +P CG P + N + + + GS + Y+C G L+G+ S +C
Sbjct: 160 ICDRIP--CGLPPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTS 217
Query: 396 D----GFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRTTHGARAL--YSCRENFTLVGNP 449
+ G WSG P C N +E+G + + DNR+ + + C+ F + G
Sbjct: 218 NDDQVGIWSGPAPQCIIPNKCTPPNVENG-ILVSDNRSLFSLNEVVEFRCQPGFVMKGPR 276
Query: 450 ERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTV---NGHKAGSLASYTCENGHILSGS 506
C W+ E P C C PP V +A T + G Y+CE G+ L G+
Sbjct: 277 RVKCQALNKWEPELPSCS-RVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGA 335
Query: 507 TSVTCTLGGAWSGVPPSCKYVNCGT--PTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNG 564
S+ CT G WS P+C+ +C + G VL G+ F C+ + L G
Sbjct: 336 ASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGR-VLFPVNLQLGAKVDFVCDEGFQLKG 394
Query: 565 AEELVC---NRDGKWSYDIPSCELTSCPEPEV-PSGGY----MEAFDY--YVHSTINFHC 614
+ C + W+ +P CE CP P V P+G + +E F + V+ T + H
Sbjct: 395 SSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHP 454
Query: 615 EAGHK--LIGEPNLVCQQD----GEWSGDSPTCEYIDCGKLPT-LPYGTMELLNGTTH-- 665
+ G LIGE + C D G WS +P C + + P + ++ +
Sbjct: 455 DRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFP 514
Query: 666 LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRS 725
+G+ ++Y C Y P TC + WS C+ C P D
Sbjct: 515 IGTSLKYECRPEY-YGRPFSITCLDNLVWSSPKDVCKRKSCKTP------------PDPV 561
Query: 726 HGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTCQY 782
+G + T D+ ++G+ + Y C G+++IG S + C +G WS P CQ
Sbjct: 562 NGMVHVIT----DI----QVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQR 613
Query: 783 VDCGNPGRIENGKVTLPSNATF-YGATAFYQCDEN------WELEGVIRRMCQEN----G 831
+ CG P I NG + F YG+ Y+C+ +EL G C N G
Sbjct: 614 IPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVG 673
Query: 832 TWSLEPPICKEITCPDPSAQIKAGSGLLVVT--STLSIGGEAHYQCERGYNLKGHQTRTC 889
WS P C P+ +G+LV S S+ ++C+ G+ +KG + C
Sbjct: 674 IWSGPAPQC---IIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKC 730
Query: 890 ISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLF-GSSVEYYCLSQYQRVGPFLRK 948
+ +W +P C + C+ P ++ + + + G V Y C Y G +
Sbjct: 731 QALNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMR 789
Query: 949 CLDDGRWSGEEPSCEL 964
C G WS P+CE+
Sbjct: 790 CTPQGDWSPAAPTCEV 805
Score = 195 bits (475), Expect = 8e-49
Identities = 185/688 (26%), Positives = 270/688 (39%), Gaps = 83/688 (12%)
Query: 345 ICQYLPPTCGSPDKLLNTTILGN---DYDVGSRIVYKC---PEGHM---LLGDKSRHCKK 395
+C+++ C +P +LN G D G I Y C P+ M L+G+ + C
Sbjct: 1315 VCEHI--FCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTS 1372
Query: 396 D----GFWSGAPPSCKY-VNCGGLT-----PIEDGDVALIDNRTTHGARALYSCRENFTL 445
D G WS P C+ V G P + + D G Y CR +
Sbjct: 1373 DPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDFEFPVGTSLNYECRPGY-- 1430
Query: 446 VGNP-ERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGH-KAGSLASYTCENGHIL 503
G +C + +W C C PP N V +N + GS +Y+C G L
Sbjct: 1431 FGKMFSISCLENLVWSSVEDNCRRKSCGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRL 1490
Query: 504 SGSTSVTCTLGG---AWSGVPPSCKYVNCGTP-TIHKGSFVLINGTTTY-GSIAQFTCE- 557
GS S TC + G W P C+ ++C P TI G F N T+ + G++ + C
Sbjct: 1491 IGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHT 1550
Query: 558 -PD----YWLNGAEELVC-NRD---GKWSYDIPSCELTS-CPEPEVPSGGYMEAFDYYVH 607
PD + L G + C ++D G WS P C T+ C PEV + + +
Sbjct: 1551 GPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRCISTNKCTAPEVENAIRVPGNRSFFS 1610
Query: 608 ST--INFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTH 665
T I F C+ G ++G + CQ +G W P C + C P + +G L +
Sbjct: 1611 LTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHCSRV-CQPPPEILHGEHTLSHQDNF 1669
Query: 666 L-GSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDR 724
G + YSC +Y L G CT + WS +PRC C D +
Sbjct: 1670 SPGQEVFYSCEPSYDLRGAASLHCTPQGDWSPEAPRCTVKSCDDFL-----------GQL 1718
Query: 725 SHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTCQ 781
HG L+ + ++GA V + C++G+++ G S S C G W+ + P C+
Sbjct: 1719 PHGRVLLPLN--------LQLGAKVSFVCDEGFRLKGRSASHCVLAGMKALWNSSVPVCE 1770
Query: 782 YVDCGNPGRIENGKVT-LPSNATFYGATAFYQCDEN------WELEGVIRRMC----QEN 830
+ C NP I NG+ T P YG Y CD + + L G C Q N
Sbjct: 1771 QIFCPNPPAILNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGESSIRCTSDPQGN 1830
Query: 831 GTWSLEPPICK---EITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTR 887
G WS P C+ CP P +I+ G + S G Y C+ GY L G
Sbjct: 1831 GVWSSPAPRCELSVPAACPHPP-KIQNGHYIGGHVSLYLPGMTISYTCDPGYLLVGKGFI 1889
Query: 888 TCISKGQWNGTVPVCIPIDCRSPGNIEN-GKIVISNGSTLFGSSVEYYCLSQYQRVGPFL 946
C +G W+ C ++C P + K + +G V C Y G
Sbjct: 1890 FCTDQGIWSQLDHYCKEVNCSFPLFMNGISKELEMKKVYHYGDYVTLKCEDGYTLEGSPW 1949
Query: 947 RKCLDDGRWSGEEPSCELATNEAVDSGT 974
+C D RW C ++A+ GT
Sbjct: 1950 SQCQADDRWDPPLAKCTSRAHDALIVGT 1977
Score = 188 bits (457), Expect = 1e-46
Identities = 173/666 (25%), Positives = 262/666 (39%), Gaps = 79/666 (11%)
Query: 353 CGSPDKLLNTTILGNDYDV---GSRIVYKC---PE---GHMLLGDKSRHCKKD----GFW 399
C SP + N G +V G + Y C P+ L+G+ + C D G W
Sbjct: 421 CPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVW 480
Query: 400 SGAPPSCKYV-NCGGLTPIEDGDVALIDNRTTH--GARALYSCRENFTLVGNP-ERTCGD 455
S P C + +C + N + G Y CR + G P TC D
Sbjct: 481 SSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEY--YGRPFSITCLD 538
Query: 456 EGIWDGEAPRCLFDWCPDPPAVSNASV-TVNGHKAGSLASYTCENGHILSGSTSVTCTLG 514
+W C C PP N V + + GS +Y+C GH L G +S C L
Sbjct: 539 NLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILS 598
Query: 515 GA---WSGVPPSCKYVNCGTP-TIHKGSFVLINGTTT-YGSIAQFTCEPD------YWLN 563
G WS PP C+ + CG P TI G F+ N YGS+ + C P + L
Sbjct: 599 GNAAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELV 658
Query: 564 GAEELVC--NRD--GKWSYDIPSCELTS-CPEPEVPSGGYMEAFD--YYVHSTINFHCEA 616
G + C N D G WS P C + + C P V +G + + ++ + F C+
Sbjct: 659 GEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQP 718
Query: 617 GHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHL-GSVIQYSCT 675
G + G + CQ +W + P+C + C P + + + G + YSC
Sbjct: 719 GFVMKGPRRVKCQALNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCE 777
Query: 676 TNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSD 735
Y L G CT + WS ++P CE C D + +G L +
Sbjct: 778 PGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDFM-----------GQLLNGRVLFPVN- 825
Query: 736 NRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTCQYVDCGNPGRIE 792
++GA V + C++G+++ G S S C G W+ + P C+ + C +P I
Sbjct: 826 -------LQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIP 878
Query: 793 NGKVT-LPSNATFYGATAFYQCD------ENWELEGVIRRMC----QENGTWSLEPPICK 841
NG+ T P +G Y CD +++L G C Q NG WS P C
Sbjct: 879 NGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCG 938
Query: 842 EI-TCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVP 900
+ C P + A S IG Y+C Y + TC+ W+
Sbjct: 939 ILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGRPFSI-TCLDNLVWSSPKD 997
Query: 901 VCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDG---RWSG 957
VC C++P + NG + + + GS + Y C + ++ +G +C+ G WS
Sbjct: 998 VCKRKSCKTPPDPVNGMVHVITDIQV-GSRINYSCTTGHRLIGHSSAECILSGNTAHWST 1056
Query: 958 EEPSCE 963
+ P C+
Sbjct: 1057 KPPICQ 1062
Score = 169 bits (411), Expect = 5e-41
Identities = 135/509 (26%), Positives = 209/509 (41%), Gaps = 59/509 (11%)
Query: 490 GSLASYTCENGHILSGST-SVTCTLGGAWSGVPPSCKYVNCGTPTIHKGSFVLINGTTTY 548
G+ +Y C G+ SG S+ C W+G C+ +C P V + +
Sbjct: 66 GTYLNYECRPGY--SGRPFSIICLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKGIQF 123
Query: 549 GSIAQFTCEPDYWLNGAEELVCNRDGK---WSYDIPSCELTSCP-EPEVPSGGYMEAF-- 602
GS +++C Y L G+ C G W + P C+ C P + +G ++
Sbjct: 124 GSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTITNGDFISTNRE 183
Query: 603 DYYVHSTINFHCEAGH------KLIGEPNLVC----QQDGEWSGDSPTCEYIDCGKLPTL 652
+++ S + + C G +L+GEP++ C Q G WSG +P C + P +
Sbjct: 184 NFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNV 243
Query: 653 PYGTMELLNGTTH-LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIV 711
G + N + L V+++ C + + GP R C +W P C + C P
Sbjct: 244 ENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRV-CQPP-- 300
Query: 712 AEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNG 771
D H R DN + G V Y CE GY + G + C G
Sbjct: 301 ----------PDVLHAERTQRDKDN------FSPGQEVFYSCEPGYDLRGAASMRCTPQG 344
Query: 772 QWSGTTPTCQYVDCGN-PGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQEN 830
WS PTC+ C + G++ NG+V P N GA + CDE ++L+G C
Sbjct: 345 DWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQL-GAKVDFVCDEGFQLKGSSASYCVLA 403
Query: 831 GT---WSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCE----RG--YNL 881
G W+ P+C++I CP P I G G +Y C+ RG ++L
Sbjct: 404 GMESLWNSSVPVCEQIFCPSPPV-IPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDL 462
Query: 882 KGHQTRTCIS----KGQWNGTVPVC-IPIDCRSPGNIENGKIVISNGSTLF--GSSVEYY 934
G T C S G W+ P C I C++P + K+ ++ F G+S++Y
Sbjct: 463 IGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYE 522
Query: 935 CLSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
C +Y PF CLD+ WS + C+
Sbjct: 523 CRPEYYG-RPFSITCLDNLVWSSPKDVCK 550
Score = 101 bits (243), Expect = 1e-20
Identities = 80/316 (25%), Positives = 124/316 (39%), Gaps = 42/316 (13%)
Query: 666 LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRS 725
+G+ + Y C Y P C + W+ + RC C +P +V V
Sbjct: 65 IGTYLNYECRPGYS-GRPFSIICLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKG--- 120
Query: 726 HGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTCQY 782
+ G+ +KY C KGY++IG S +TC +G W TP C
Sbjct: 121 -----------------IQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDR 163
Query: 783 VDCGNPGRIENGKVTLPSNATF-YGATAFYQCDEN------WELEGVIRRMCQEN----G 831
+ CG P I NG + F YG+ Y+C+ +EL G C N G
Sbjct: 164 IPCGLPPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVG 223
Query: 832 TWSLEPPICKEITCPDPSAQIKAGSGLLVV--TSTLSIGGEAHYQCERGYNLKGHQTRTC 889
WS P C P+ +G+LV S S+ ++C+ G+ +KG + C
Sbjct: 224 IWSGPAPQC---IIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKC 280
Query: 890 ISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLF-GSSVEYYCLSQYQRVGPFLRK 948
+ +W +P C + C+ P ++ + + + G V Y C Y G +
Sbjct: 281 QALNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMR 339
Query: 949 CLDDGRWSGEEPSCEL 964
C G WS P+CE+
Sbjct: 340 CTPQGDWSPAAPTCEV 355
Score = 44.0 bits (99), Expect = 0.003
Identities = 17/42 (40%), Positives = 24/42 (57%)
Query: 17 NEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
+++N G Y C+ GY+L GA CT +GDW+ E P C
Sbjct: 1212 HQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGDWSPEAPRC 1253
Score = 42.7 bits (96), Expect = 0.007
Identities = 18/57 (31%), Positives = 28/57 (49%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C P + ++ +++N G Y C+ Y+L GA CT +GDW+ E P C
Sbjct: 1650 CQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCTPQGDWSPEAPRC 1706
Score = 42.3 bits (95), Expect = 0.009
Identities = 19/57 (33%), Positives = 28/57 (49%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C P +A + +++N G Y C+ GY+L GA CT +GDW+ P C
Sbjct: 297 CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTC 353
Score = 42.3 bits (95), Expect = 0.009
Identities = 19/57 (33%), Positives = 28/57 (49%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C P +A + +++N G Y C+ GY+L GA CT +GDW+ P C
Sbjct: 747 CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTC 803
Score = 37.5 bits (83), Expect = 0.26
Identities = 20/60 (33%), Positives = 27/60 (45%), Gaps = 5/60 (8%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGD---WTLEPPFC 58
C +P P N V + + I G+ Y C +GY L G+ C + GD W E P C
Sbjct: 104 CRNPPDPVNGMVHVI--KGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPIC 161
Score = 37.5 bits (83), Expect = 0.26
Identities = 20/60 (33%), Positives = 27/60 (45%), Gaps = 5/60 (8%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGD---WTLEPPFC 58
C P P N V + + I G+ Y C G+ L G EC L G+ W+ +PP C
Sbjct: 554 CKTPPDPVNGMVHVITD--IQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPIC 611
Score = 37.5 bits (83), Expect = 0.26
Identities = 20/60 (33%), Positives = 27/60 (45%), Gaps = 5/60 (8%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGD---WTLEPPFC 58
C P P N V + + I G+ Y C G+ L G EC L G+ W+ +PP C
Sbjct: 1004 CKTPPDPVNGMVHVITD--IQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPIC 1061
Score = 37.5 bits (83), Expect = 0.26
Identities = 19/60 (31%), Positives = 27/60 (45%), Gaps = 5/60 (8%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGD---WTLEPPFC 58
CG P P N V I + G+ Y C+EG+ L G+ C + G+ W + P C
Sbjct: 1457 CGPPPEPFNGMVHINTDTQF--GSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPIC 1514
>X05309-1|CAA28933.1| 1537|Homo sapiens protein ( Human mRNA for
C3b/C4b receptor (CR1) F allotype. ).
Length = 1537
Score = 234 bits (573), Expect = 1e-60
Identities = 194/665 (29%), Positives = 275/665 (41%), Gaps = 78/665 (11%)
Query: 352 TCGSPDKLLNTTI-LGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDG---FWSGAPPSCK 407
+C +P +N + + D VGSRI Y C GH L+G S C G WS PP C+
Sbjct: 51 SCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQ 110
Query: 408 YVNCGGLTPIEDGDVALIDNRTTH-GARALYSC------RENFTLVGNPERTC--GDE-- 456
+ CG I +GD + H G+ Y C R+ F LVG P C D+
Sbjct: 111 RIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQV 170
Query: 457 GIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGSL---ASYTCENGHILSGSTSVTCTL 513
GIW G AP+C+ PP V N + + SL + C+ G ++ G V C
Sbjct: 171 GIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQA 230
Query: 514 GGAWSGVPPSCKYVNCGTP--TIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCN 571
W PSC V C P +H + G ++CEP Y L GA + C
Sbjct: 231 LNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCT 289
Query: 572 RDGKWSYDIPSCELTSCPE--PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQ 629
G WS P+CE+ SC + ++ +G + + + + ++F C+ G +L G C
Sbjct: 290 PQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCV 349
Query: 630 QDGE---WSGDSPTCEYIDCGKLPTLPYG--TMELLNGTTHLGSVIQYSCT------TNY 678
G W+ P CE I C P +P G T + L G + Y+C T++
Sbjct: 350 LAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLE-VFPFGKAVNYTCDPHPDRGTSF 408
Query: 679 RLVGPVRRTCTEEFQ----WSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTS 734
L+G CT + Q WS +PRC + G+ ++ H L
Sbjct: 409 DLIGESTIRCTSDPQGNGVWSSPAPRC----------------GILGHCQAPDHFLFAKL 452
Query: 735 DNRDVGNTYRIGALVKYRCEKGYKVIGESLS-TCEDNGQWSGTTPTCQYVDCGNPGRIEN 793
+ + + IG +KY C Y G S TC DN WS C+ C P N
Sbjct: 453 KTQTNASDFPIGTSLKYECRPEY--YGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVN 510
Query: 794 GKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGT---WSLEPPICKEITCPDPSA 850
G V + ++ G+ Y C L G C +G WS +PPIC+ I C P
Sbjct: 511 GMVHVITDIQV-GSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPCGLPPT 569
Query: 851 QIKAGSGLLVVTSTLSIGGEAHYQCERG------YNLKGHQTRTCISK----GQWNGTVP 900
I G + G Y+C G + L G + C S G W+G P
Sbjct: 570 -IANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAP 628
Query: 901 VC-IPIDCRSPGNIENGKIVISNGSTLFGSS--VEYYCLSQYQRVGPFLRKCLDDGRWSG 957
C IP C +P N+ENG I++S+ +LF + VE+ C + GP KC +W
Sbjct: 629 QCIIPNKC-TPPNVENG-ILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEP 686
Query: 958 EEPSC 962
E PSC
Sbjct: 687 ELPSC 691
Score = 227 bits (555), Expect = 2e-58
Identities = 187/662 (28%), Positives = 274/662 (41%), Gaps = 69/662 (10%)
Query: 352 TCGSPDKLLNTTI-LGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDG---FWSGAPPSCK 407
+C +P +N + + D VGSRI Y C GH L+G S C G WS PP C+
Sbjct: 501 SCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQ 560
Query: 408 YVNCGGLTPIEDGDVALIDNRTTH-GARALYSC------RENFTLVGNPERTC--GDE-- 456
+ CG I +GD + H G+ Y C R+ F LVG P C D+
Sbjct: 561 RIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQV 620
Query: 457 GIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGSL---ASYTCENGHILSGSTSVTCTL 513
GIW G AP+C+ PP V N + + SL + C+ G ++ G V C
Sbjct: 621 GIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQA 680
Query: 514 GGAWSGVPPSCKYVNCGTPTIHKGSFVLINGTT-TYGSIAQFTCEPDYWLNGAEELVCNR 572
W PSC V P I G + + G ++CEP Y L GA L C
Sbjct: 681 LNKWEPELPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTP 740
Query: 573 DGKWSYDIPSCELTSCPE--PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQ 630
G WS + P C + SC + ++P G + + + + ++F C+ G +L G C
Sbjct: 741 QGDWSPEAPRCAVKSCDDFLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCVL 800
Query: 631 DGE---WSGDSPTCEYIDCGKLPTLPYGT-MELLNGTTHLGSVIQYSCTTN------YRL 680
G W+ P CE+I C P + G +G G I Y+C + + L
Sbjct: 801 VGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNL 860
Query: 681 VGPVRRTCTEEFQ----WSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDN 736
+G CT + WS +PRCE ++ ++ T I +D
Sbjct: 861 IGESTIRCTSDPHGNGVWSSPAPRCE--------LSVRAGHCKTPEQFPFASPTIPINDF 912
Query: 737 RDVGNTYRIGALVKYRCEKGYKVIGESLS-TCEDNGQWSGTTPTCQYVDCGNPGRIENGK 795
+ +G + Y C GY G+ S +C +N WS C+ CG P NG
Sbjct: 913 E-----FPVGTSLNYECRPGY--FGKMFSISCLENLVWSSVEDNCRRKSCGPPPEPFNGM 965
Query: 796 VTLPSNATFYGATAFYQCDENWELEGVIRRMCQENG---TWSLEPPICKEITCPDPSAQI 852
V + ++ T +G+T Y C+E + L G C +G TW + PIC+ I+C +P I
Sbjct: 966 VHINTD-TQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISC-EPPPTI 1023
Query: 853 KAGSGLLVVTSTLSIGGEAHYQCERG------YNLKGHQTRTCISK----GQWNGTVPVC 902
G ++ G YQC G + L G ++ C SK G W+ P C
Sbjct: 1024 SNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRC 1083
Query: 903 IPID-CRSPGNIENGKIVISNGSTL-FGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEP 960
I + C +P +EN V N S + + C + VG +C +GRW + P
Sbjct: 1084 ISTNKCTAP-EVENAIRVPGNRSFFSLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLP 1142
Query: 961 SC 962
C
Sbjct: 1143 HC 1144
Score = 205 bits (501), Expect = 6e-52
Identities = 178/668 (26%), Positives = 269/668 (40%), Gaps = 72/668 (10%)
Query: 353 CGSPDKLL----NTTILGNDYDVGSRIVYKC-PEGHMLLGDKSRHCKKDGFWSGAPPSCK 407
C +PD L T +D+ +G+ + Y+C PE + S C + WS CK
Sbjct: 441 CQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGR--PFSITCLDNLVWSSPKDVCK 498
Query: 408 YVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTC---GDEGIWDGEAP 464
+C +G V +I + G+R YSC L+G+ C G+ W + P
Sbjct: 499 RKSCKTPPDPVNGMVHVITDIQV-GSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPP 557
Query: 465 RCLFDWCPDPPAVSNAS-VTVNGHKA--GSLASYTCENGHI------LSGSTSVTCTLG- 514
C C PP ++N ++ N GS+ +Y C G L G S+ CT
Sbjct: 558 ICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSND 617
Query: 515 ---GAWSGVPPSCKYVN-CGTPTIHKGSFVLINGTT-TYGSIAQFTCEPDYWLNGAEELV 569
G WSG P C N C P + G V N + + + +F C+P + + G +
Sbjct: 618 DQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVK 677
Query: 570 CNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAF--DYYVHSTINFHCEAGHKLIGEPNLV 627
C KW ++PSC P PE+ G + + ++ + + CE G+ L G +L
Sbjct: 678 CQALNKWEPELPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLH 737
Query: 628 CQQDGEWSGDSPTCEYIDCGK-LPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRR 686
C G+WS ++P C C L LP+G + L LG+ + + C +RL G
Sbjct: 738 CTPQGDWSPEAPRCAVKSCDDFLGQLPHGRV-LFPLNLQLGAKVSFVCDEGFRLKGSSVS 796
Query: 687 TCT---EEFQWSDSSPRCEEIRCSDP-IVAEKSIVSVTGNDRSHGHTLIRTSD-NRDVGN 741
C W++S P CE I C +P + D +G + T D + D G
Sbjct: 797 HCVLVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGM 856
Query: 742 TYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYV----DCGNPGRIENGKVT 797
T+ + RC S NG WS P C+ C P + T
Sbjct: 857 TFNLIGESTIRCT----------SDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPT 906
Query: 798 LPSNATFY--GATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAG 855
+P N + G + Y+C + + C EN WS C+ +C P
Sbjct: 907 IPINDFEFPVGTSLNYECRPGY-FGKMFSISCLENLVWSSVEDNCRRKSCGPPPEPF--- 962
Query: 856 SGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQ---WNGTVPVCIPIDCRSPGN 912
+G++ + + G +Y C G+ L G + TC+ G W+ P+C I C P
Sbjct: 963 NGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPT 1022
Query: 913 IENGKIVISNGSTLF--GSSVEYYCLS------QYQRVGPFLRKCL--DD--GRWSGEEP 960
I NG SN T F G+ V Y C + ++ VG C DD G WS P
Sbjct: 1023 ISNGDF-YSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPP 1081
Query: 961 SCELATNE 968
C ++TN+
Sbjct: 1082 RC-ISTNK 1088
Score = 200 bits (487), Expect = 3e-50
Identities = 170/650 (26%), Positives = 256/650 (39%), Gaps = 79/650 (12%)
Query: 371 VGSRIVYKCPEGHMLLGDKSRHCKKDGF---WSGAPPSCKYVNCGGLTPIEDG-DVALID 426
+G+++ + C EG L G HC G W+ + P C+++ C I +G
Sbjct: 776 LGAKVSFVCDEGFRLKGSSVSHCVLVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPS 835
Query: 427 NRTTHGARALYSCREN------FTLVGNPERTCGDE----GIWDGEAPRCLFD----WCP 472
+G Y+C + F L+G C + G+W APRC C
Sbjct: 836 GDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTSDPHGNGVWSSPAPRCELSVRAGHCK 895
Query: 473 DPPAVSNASVTV--NGHK--AGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVN 528
P AS T+ N + G+ +Y C G+ S++C WS V +C+ +
Sbjct: 896 TPEQFPFASPTIPINDFEFPVGTSLNYECRPGYF-GKMFSISCLENLVWSSVEDNCRRKS 954
Query: 529 CGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGK---WSYDIPSCEL 585
CG P V IN T +GS ++C + L G+ C G W P CE+
Sbjct: 955 CGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEI 1014
Query: 586 TSC-PEPEVPSGGYM--EAFDYYVHSTINFHCEAG------HKLIGEPNLVC----QQDG 632
SC P P + +G + ++ + + + C G +L+GE ++ C Q G
Sbjct: 1015 ISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVG 1074
Query: 633 EWSGDSPTCEYIDCGKLPTLPYGTMELLNGT-THLGSVIQYSCTTNYRLVGPVRRTCTEE 691
WS P C + P + N + L +I++ C + +VG C
Sbjct: 1075 VWSSPPPRCISTNKCTAPEVENAIRVPGNRSFFSLTEIIRFRCQPGFVMVGSHTVQCQTN 1134
Query: 692 FQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKY 751
+W P C + C P + HG + DN + G V Y
Sbjct: 1135 GRWGPKLPHCSRV-CQPP------------PEILHGEHTLSHQDN------FSPGQEVFY 1175
Query: 752 RCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGN-PGRIENGKVTLPSNATFYGATAF 810
CE Y + G + C G WS P C C + G++ +G+V LP N GA
Sbjct: 1176 SCEPSYDLRGAASLHCTPQGDWSPEAPRCTVKSCDDFLGQLPHGRVLLPLNLQL-GAKVS 1234
Query: 811 YQCDENWELEGVIRRMCQENG---TWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSI 867
+ CDE + L+G C G W+ P+C++I CP+P A I G +
Sbjct: 1235 FVCDEGFRLKGRSASHCVLAGMKALWNSSVPVCEQIFCPNPPA-ILNGRHTGTPFGDIPY 1293
Query: 868 GGEAHYQC----ERG--YNLKGHQTRTCIS----KGQWNGTVPVC---IPIDCRSPGNIE 914
G E Y C +RG +NL G + C S G W+ P C +P C P I+
Sbjct: 1294 GKEISYACDTHPDRGMTFNLIGESSIRCTSDPQGNGVWSSPAPRCELSVPAACPHPPKIQ 1353
Query: 915 NGKIVISNGST-LFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
NG + + S L G ++ Y C Y VG C D G WS + C+
Sbjct: 1354 NGHYIGGHVSLYLPGMTISYTCDPGYLLVGKGFIFCTDQGIWSQLDHYCK 1403
Score = 196 bits (479), Expect = 3e-49
Identities = 181/674 (26%), Positives = 263/674 (39%), Gaps = 82/674 (12%)
Query: 353 CGSPDKLLNTTILGNDYDV---GSRIVYKC---PE---GHMLLGDKSRHCKKD----GFW 399
C SP + N G +V G + Y C P+ L+G+ + C D G W
Sbjct: 369 CPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVW 428
Query: 400 SGAPPSCKYV-NCGGLTPIEDGDVALIDNRTTH--GARALYSCRENFTLVGNP-ERTCGD 455
S P C + +C + N + G Y CR + G P TC D
Sbjct: 429 SSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEY--YGRPFSITCLD 486
Query: 456 EGIWDGEAPRCLFDWCPDPPAVSNASV-TVNGHKAGSLASYTCENGHILSGSTSVTCTLG 514
+W C C PP N V + + GS +Y+C GH L G +S C L
Sbjct: 487 NLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILS 546
Query: 515 GA---WSGVPPSCKYVNCGTP-TIHKGSFVLINGTTT-YGSIAQFTCEPD------YWLN 563
G WS PP C+ + CG P TI G F+ N YGS+ + C + L
Sbjct: 547 GNTAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELV 606
Query: 564 GAEELVC--NRD--GKWSYDIPSCELTS-CPEPEVPSGGYMEAFD--YYVHSTINFHCEA 616
G + C N D G WS P C + + C P V +G + + ++ + F C+
Sbjct: 607 GEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQP 666
Query: 617 GHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHL-GSVIQYSCT 675
G + G + CQ +W + P+C + C P + +G + G + YSC
Sbjct: 667 GFVMKGPRRVKCQALNKWEPELPSCSRV-CQPPPEILHGEHTPSHQDNFSPGQEVFYSCE 725
Query: 676 TNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSD 735
Y L G CT + WS +PRC C D + HG L +
Sbjct: 726 PGYDLRGAASLHCTPQGDWSPEAPRCAVKSCDDFL-----------GQLPHGRVLFPLN- 773
Query: 736 NRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTCQYVDCGNPGRIE 792
++GA V + C++G+++ G S+S C G W+ + P C+++ C NP I
Sbjct: 774 -------LQLGAKVSFVCDEGFRLKGSSVSHCVLVGMRSLWNNSVPVCEHIFCPNPPAIL 826
Query: 793 NGKVT-LPSNATFYGATAFYQCDEN------WELEGVIRRMCQE----NGTWSLEPPICK 841
NG+ T PS YG Y CD + + L G C NG WS P C+
Sbjct: 827 NGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTSDPHGNGVWSSPAPRCE 886
Query: 842 EIT----CPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNG 897
C P A + + +G +Y+C GY K +C+ W+
Sbjct: 887 LSVRAGHCKTPEQFPFASPTIPINDFEFPVGTSLNYECRPGYFGKMFSI-SCLENLVWSS 945
Query: 898 TVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGR--- 954
C C P NG + I N T FGS+V Y C ++ +G CL G
Sbjct: 946 VEDNCRRKSCGPPPEPFNGMVHI-NTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVT 1004
Query: 955 WSGEEPSCELATNE 968
W + P CE+ + E
Sbjct: 1005 WDKKAPICEIISCE 1018
Score = 195 bits (475), Expect = 8e-49
Identities = 185/688 (26%), Positives = 270/688 (39%), Gaps = 83/688 (12%)
Query: 345 ICQYLPPTCGSPDKLLNTTILGN---DYDVGSRIVYKC---PEGHM---LLGDKSRHCKK 395
+C+++ C +P +LN G D G I Y C P+ M L+G+ + C
Sbjct: 813 VCEHI--FCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTS 870
Query: 396 D----GFWSGAPPSCKY-VNCGGLT-----PIEDGDVALIDNRTTHGARALYSCRENFTL 445
D G WS P C+ V G P + + D G Y CR +
Sbjct: 871 DPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDFEFPVGTSLNYECRPGY-- 928
Query: 446 VGNP-ERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGH-KAGSLASYTCENGHIL 503
G +C + +W C C PP N V +N + GS +Y+C G L
Sbjct: 929 FGKMFSISCLENLVWSSVEDNCRRKSCGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRL 988
Query: 504 SGSTSVTCTLGG---AWSGVPPSCKYVNCGTP-TIHKGSFVLINGTTTY-GSIAQFTCE- 557
GS S TC + G W P C+ ++C P TI G F N T+ + G++ + C
Sbjct: 989 IGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHT 1048
Query: 558 -PD----YWLNGAEELVC-NRD---GKWSYDIPSCELTS-CPEPEVPSGGYMEAFDYYVH 607
PD + L G + C ++D G WS P C T+ C PEV + + +
Sbjct: 1049 GPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRCISTNKCTAPEVENAIRVPGNRSFFS 1108
Query: 608 ST--INFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTH 665
T I F C+ G ++G + CQ +G W P C + C P + +G L +
Sbjct: 1109 LTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHCSRV-CQPPPEILHGEHTLSHQDNF 1167
Query: 666 L-GSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDR 724
G + YSC +Y L G CT + WS +PRC C D +
Sbjct: 1168 SPGQEVFYSCEPSYDLRGAASLHCTPQGDWSPEAPRCTVKSCDDFL-----------GQL 1216
Query: 725 SHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTCQ 781
HG L+ + ++GA V + C++G+++ G S S C G W+ + P C+
Sbjct: 1217 PHGRVLLPLN--------LQLGAKVSFVCDEGFRLKGRSASHCVLAGMKALWNSSVPVCE 1268
Query: 782 YVDCGNPGRIENGKVT-LPSNATFYGATAFYQCDEN------WELEGVIRRMC----QEN 830
+ C NP I NG+ T P YG Y CD + + L G C Q N
Sbjct: 1269 QIFCPNPPAILNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGESSIRCTSDPQGN 1328
Query: 831 GTWSLEPPICK---EITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTR 887
G WS P C+ CP P +I+ G + S G Y C+ GY L G
Sbjct: 1329 GVWSSPAPRCELSVPAACPHPP-KIQNGHYIGGHVSLYLPGMTISYTCDPGYLLVGKGFI 1387
Query: 888 TCISKGQWNGTVPVCIPIDCRSPGNIEN-GKIVISNGSTLFGSSVEYYCLSQYQRVGPFL 946
C +G W+ C ++C P + K + +G V C Y G
Sbjct: 1388 FCTDQGIWSQLDHYCKEVNCSFPLFMNGISKELEMKKVYHYGDYVTLKCEDGYTLEGSPW 1447
Query: 947 RKCLDDGRWSGEEPSCELATNEAVDSGT 974
+C D RW C ++A+ GT
Sbjct: 1448 SQCQADDRWDPPLAKCTSRAHDALIVGT 1475
Score = 182 bits (444), Expect = 5e-45
Identities = 152/571 (26%), Positives = 230/571 (40%), Gaps = 63/571 (11%)
Query: 432 GARALYSCRENFTLVGNP-ERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASV-TVNGHKA 489
G Y CR + G P TC D +W C C PP N V + +
Sbjct: 14 GTSLKYECRPEY--YGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQV 71
Query: 490 GSLASYTCENGHILSGSTSVTCTLGGA---WSGVPPSCKYVNCGTP-TIHKGSFVLINGT 545
GS +Y+C GH L G +S C L G WS PP C+ + CG P TI G F+ N
Sbjct: 72 GSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTNRE 131
Query: 546 TT-YGSIAQFTCEPD------YWLNGAEELVC--NRD--GKWSYDIPSCELTS-CPEPEV 593
YGS+ + C P + L G + C N D G WS P C + + C P V
Sbjct: 132 NFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNV 191
Query: 594 PSGGYMEAFD--YYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPT 651
+G + + ++ + F C+ G + G + CQ +W + P+C + C P
Sbjct: 192 ENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRV-CQPPPD 250
Query: 652 LPYGTMELLNGTTHL-GSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPI 710
+ + + G + YSC Y L G CT + WS ++P CE C D +
Sbjct: 251 VLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDFM 310
Query: 711 VAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDN 770
+G L + ++GA V + C++G+++ G S S C
Sbjct: 311 -----------GQLLNGRVLFPVN--------LQLGAKVDFVCDEGFQLKGSSASYCVLA 351
Query: 771 GQ---WSGTTPTCQYVDCGNPGRIENGKVT-LPSNATFYGATAFYQCD------ENWELE 820
G W+ + P C+ + C +P I NG+ T P +G Y CD +++L
Sbjct: 352 GMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLI 411
Query: 821 GVIRRMC----QENGTWSLEPPICKEI-TCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQC 875
G C Q NG WS P C + C P + A S IG Y+C
Sbjct: 412 GESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYEC 471
Query: 876 ERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYC 935
Y + TC+ W+ VC C++P + NG + + + GS + Y C
Sbjct: 472 RPEYYGRPFSI-TCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQV-GSRINYSC 529
Query: 936 LSQYQRVGPFLRKCLDDG---RWSGEEPSCE 963
+ ++ +G +C+ G WS + P C+
Sbjct: 530 TTGHRLIGHSSAECILSGNTAHWSTKPPICQ 560
Score = 96.7 bits (230), Expect = 4e-19
Identities = 80/316 (25%), Positives = 127/316 (40%), Gaps = 42/316 (13%)
Query: 666 LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRS 725
+G+ ++Y C Y P TC + WS C+ C P D
Sbjct: 13 IGTSLKYECRPEY-YGRPFSITCLDNLVWSSPKDVCKRKSCKTP------------PDPV 59
Query: 726 HGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTCQY 782
+G + T D+ ++G+ + Y C G+++IG S + C +G WS P CQ
Sbjct: 60 NGMVHVIT----DI----QVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQR 111
Query: 783 VDCGNPGRIENGKVTLPSNATF-YGATAFYQCDEN------WELEGVIRRMCQEN----G 831
+ CG P I NG + F YG+ Y+C+ +EL G C N G
Sbjct: 112 IPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVG 171
Query: 832 TWSLEPPICKEITCPDPSAQIKAGSGLLVVT--STLSIGGEAHYQCERGYNLKGHQTRTC 889
WS P C P+ +G+LV S S+ ++C+ G+ +KG + C
Sbjct: 172 IWSGPAPQC---IIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKC 228
Query: 890 ISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLF-GSSVEYYCLSQYQRVGPFLRK 948
+ +W +P C + C+ P ++ + + + G V Y C Y G +
Sbjct: 229 QALNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMR 287
Query: 949 CLDDGRWSGEEPSCEL 964
C G WS P+CE+
Sbjct: 288 CTPQGDWSPAAPTCEV 303
Score = 94.3 bits (224), Expect = 2e-18
Identities = 75/237 (31%), Positives = 100/237 (42%), Gaps = 23/237 (9%)
Query: 743 YRIGALVKYRCEKGYKVIGESLS-TCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSN 801
+ IG +KY C Y G S TC DN WS C+ C P NG V + ++
Sbjct: 11 FPIGTSLKYECRPEY--YGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITD 68
Query: 802 ATFYGATAFYQCDENWELEGVIRRMCQENGT---WSLEPPICKEITCPDPSAQIKAGSGL 858
G+ Y C L G C +G WS +PPIC+ I C P I G +
Sbjct: 69 IQV-GSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPT-IANGDFI 126
Query: 859 LVVTSTLSIGGEAHYQCERG------YNLKGHQTRTCISK----GQWNGTVPVC-IPIDC 907
G Y+C G + L G + C S G W+G P C IP C
Sbjct: 127 STNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKC 186
Query: 908 RSPGNIENGKIVISNGSTLFGSS--VEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
+P N+ENG I++S+ +LF + VE+ C + GP KC +W E PSC
Sbjct: 187 -TPPNVENG-ILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSC 241
Score = 44.0 bits (99), Expect = 0.003
Identities = 17/42 (40%), Positives = 24/42 (57%)
Query: 17 NEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
+++N G Y C+ GY+L GA CT +GDW+ E P C
Sbjct: 710 HQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGDWSPEAPRC 751
Score = 42.7 bits (96), Expect = 0.007
Identities = 18/57 (31%), Positives = 28/57 (49%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C P + ++ +++N G Y C+ Y+L GA CT +GDW+ E P C
Sbjct: 1148 CQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCTPQGDWSPEAPRC 1204
Score = 42.3 bits (95), Expect = 0.009
Identities = 19/57 (33%), Positives = 28/57 (49%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C P +A + +++N G Y C+ GY+L GA CT +GDW+ P C
Sbjct: 245 CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTC 301
Score = 37.5 bits (83), Expect = 0.26
Identities = 20/60 (33%), Positives = 27/60 (45%), Gaps = 5/60 (8%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGD---WTLEPPFC 58
C P P N V + + I G+ Y C G+ L G EC L G+ W+ +PP C
Sbjct: 52 CKTPPDPVNGMVHVITD--IQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPIC 109
Score = 37.5 bits (83), Expect = 0.26
Identities = 20/60 (33%), Positives = 27/60 (45%), Gaps = 5/60 (8%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGD---WTLEPPFC 58
C P P N V + + I G+ Y C G+ L G EC L G+ W+ +PP C
Sbjct: 502 CKTPPDPVNGMVHVITD--IQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPIC 559
Score = 37.5 bits (83), Expect = 0.26
Identities = 19/60 (31%), Positives = 27/60 (45%), Gaps = 5/60 (8%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGD---WTLEPPFC 58
CG P P N V I + G+ Y C+EG+ L G+ C + G+ W + P C
Sbjct: 955 CGPPPEPFNGMVHINTDTQF--GSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPIC 1012
>L17418-2|AAB60694.1| 2039|Homo sapiens complement receptor 1 protein.
Length = 2039
Score = 234 bits (573), Expect = 1e-60
Identities = 194/665 (29%), Positives = 275/665 (41%), Gaps = 78/665 (11%)
Query: 352 TCGSPDKLLNTTI-LGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDG---FWSGAPPSCK 407
+C +P +N + + D VGSRI Y C GH L+G S C G WS PP C+
Sbjct: 553 SCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQ 612
Query: 408 YVNCGGLTPIEDGDVALIDNRTTH-GARALYSC------RENFTLVGNPERTC--GDE-- 456
+ CG I +GD + H G+ Y C R+ F LVG P C D+
Sbjct: 613 RIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQV 672
Query: 457 GIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGSL---ASYTCENGHILSGSTSVTCTL 513
GIW G AP+C+ PP V N + + SL + C+ G ++ G V C
Sbjct: 673 GIWSGPAPQCIXPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQA 732
Query: 514 GGAWSGVPPSCKYVNCGTP--TIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCN 571
W PSC V C P +H + G ++CEP Y L GA + C
Sbjct: 733 LNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCT 791
Query: 572 RDGKWSYDIPSCELTSCPE--PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQ 629
G WS P+CE+ SC + ++ +G + + + + ++F C+ G +L G C
Sbjct: 792 PQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCV 851
Query: 630 QDGE---WSGDSPTCEYIDCGKLPTLPYG--TMELLNGTTHLGSVIQYSCT------TNY 678
G W+ P CE I C P +P G T + L G + Y+C T++
Sbjct: 852 LAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLE-VFPFGKAVNYTCDPHPDRGTSF 910
Query: 679 RLVGPVRRTCTEEFQ----WSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTS 734
L+G CT + Q WS +PRC + G+ ++ H L
Sbjct: 911 DLIGESTIRCTSDPQGNGVWSSPAPRC----------------GILGHCQAPDHFLFAKL 954
Query: 735 DNRDVGNTYRIGALVKYRCEKGYKVIGESLS-TCEDNGQWSGTTPTCQYVDCGNPGRIEN 793
+ + + IG +KY C Y G S TC DN WS C+ C P N
Sbjct: 955 KTQTNASDFPIGTSLKYECRPEY--YGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVN 1012
Query: 794 GKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGT---WSLEPPICKEITCPDPSA 850
G V + ++ G+ Y C L G C +G WS +PPIC+ I C P
Sbjct: 1013 GMVHVITDIXV-GSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPCGLPPT 1071
Query: 851 QIKAGSGLLVVTSTLSIGGEAHYQCERG------YNLKGHQTRTCISK----GQWNGTVP 900
I G + G Y+C G + L G + C S G W+G P
Sbjct: 1072 -IANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAP 1130
Query: 901 VC-IPIDCRSPGNIENGKIVISNGSTLFGSS--VEYYCLSQYQRVGPFLRKCLDDGRWSG 957
C IP C +P N+ENG I++S+ +LF + VE+ C + GP KC +W
Sbjct: 1131 QCIIPNKC-TPPNVENG-ILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEP 1188
Query: 958 EEPSC 962
E PSC
Sbjct: 1189 ELPSC 1193
Score = 227 bits (555), Expect = 2e-58
Identities = 188/662 (28%), Positives = 274/662 (41%), Gaps = 69/662 (10%)
Query: 352 TCGSPDKLLNTTI-LGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDG---FWSGAPPSCK 407
+C +P +N + + D VGSRI Y C GH L+G S C G WS PP C+
Sbjct: 1003 SCKTPPDPVNGMVHVITDIXVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQ 1062
Query: 408 YVNCGGLTPIEDGDVALIDNRTTH-GARALYSC------RENFTLVGNPERTC--GDE-- 456
+ CG I +GD + H G+ Y C R+ F LVG P C D+
Sbjct: 1063 RIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQV 1122
Query: 457 GIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGSL---ASYTCENGHILSGSTSVTCTL 513
GIW G AP+C+ PP V N + + SL + C+ G ++ G V C
Sbjct: 1123 GIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQA 1182
Query: 514 GGAWSGVPPSCKYVNCGTPTIHKGSFVLINGTT-TYGSIAQFTCEPDYWLNGAEELVCNR 572
W PSC V P I G + + G ++CEP Y L GA L C
Sbjct: 1183 LNKWEPELPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTP 1242
Query: 573 DGKWSYDIPSCELTSCPE--PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQ 630
G WS + P C + SC + ++P G + + + + ++F C+ G +L G C
Sbjct: 1243 QGDWSPEAPRCAVKSCDDFLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCVL 1302
Query: 631 DGE---WSGDSPTCEYIDCGKLPTLPYGT-MELLNGTTHLGSVIQYSCTTN------YRL 680
G W+ P CE+I C P + G +G G I Y+C + + L
Sbjct: 1303 VGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNL 1362
Query: 681 VGPVRRTCTEEFQ----WSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDN 736
+G CT + WS +PRCE ++ ++ T I +D
Sbjct: 1363 IGESTIRCTSDPHGNGVWSSPAPRCE--------LSVRAGHCKTPEQFPFASPTIPINDF 1414
Query: 737 RDVGNTYRIGALVKYRCEKGYKVIGESLS-TCEDNGQWSGTTPTCQYVDCGNPGRIENGK 795
+ +G + Y C GY G+ S +C +N WS C+ CG P NG
Sbjct: 1415 E-----FPVGTSLNYECRPGY--FGKMFSISCLENLVWSSVEDNCRRKSCGPPPEPFNGM 1467
Query: 796 VTLPSNATFYGATAFYQCDENWELEGVIRRMCQENG---TWSLEPPICKEITCPDPSAQI 852
V + ++ T +G+T Y C+E + L G C +G TW + PIC+ I+C +P I
Sbjct: 1468 VHINTD-TQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISC-EPPPTI 1525
Query: 853 KAGSGLLVVTSTLSIGGEAHYQCERG------YNLKGHQTRTCISK----GQWNGTVPVC 902
G ++ G YQC G + L G ++ C SK G W+ P C
Sbjct: 1526 SNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRC 1585
Query: 903 IPID-CRSPGNIENGKIVISNGSTL-FGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEP 960
I + C +P +EN V N S V + C + VG +C +GRW + P
Sbjct: 1586 ISTNKCTAP-EVENAIRVPGNRSFFSLTEIVRFRCQPGFVMVGSHTVQCQTNGRWGPKLP 1644
Query: 961 SC 962
C
Sbjct: 1645 HC 1646
Score = 224 bits (547), Expect = 2e-57
Identities = 175/645 (27%), Positives = 261/645 (40%), Gaps = 74/645 (11%)
Query: 368 DYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDN 427
++ +G+ + Y+C G+ S C K+ W+GA C+ +C +G V +I
Sbjct: 62 EFPIGTYLNYECRPGYSGR-PFSIICLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKG 120
Query: 428 RTTHGARALYSCRENFTLVGNPERTC---GDEGIWDGEAPRCLFDWCPDPPAVSNA---S 481
G++ YSC + + L+G+ TC GD IWD E P C C PP ++N S
Sbjct: 121 -IQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTITNGDFIS 179
Query: 482 VTVNGHKAGSLASYTCENG------HILSGSTSVTCTLG----GAWSGVPPSCKYVN-CG 530
GS+ +Y C G L G S+ CT G WSG P C N C
Sbjct: 180 TNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCT 239
Query: 531 TPTIHKGSFVLINGTT-TYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCP 589
P + G V N + + + +F C+P + + G + C KW ++PSC P
Sbjct: 240 PPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQP 299
Query: 590 EPEV--PSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCG 647
P+V + ++ + + CE G+ L G ++ C G+WS +PTCE C
Sbjct: 300 PPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCD 359
Query: 648 KLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCT---EEFQWSDSSPRCEEI 704
L LG+ + + C ++L G C E W+ S P CE+I
Sbjct: 360 DFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQI 419
Query: 705 RCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCE------KGYK 758
C P V N R G L + G V Y C+ +
Sbjct: 420 FCPSP--------PVIPNGRHTGKPL----------EVFPFGKAVNYTCDPHPDRGTSFD 461
Query: 759 VIGESLSTC----EDNGQWSGTTPTCQYV-DCGNPGRIENGKVTLPSNATFY--GATAFY 811
+IGES C + NG WS P C + C P K+ +NA+ + G + Y
Sbjct: 462 LIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKY 521
Query: 812 QCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEA 871
+C + C +N WS +CK +C P + +G++ V + + +G
Sbjct: 522 ECRPEY-YGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPV---NGMVHVITDIQVGSRI 577
Query: 872 HYQCERGYNLKGHQTRTCISKG---QWNGTVPVCIPIDCRSPGNIENGKIVISNGSTL-F 927
+Y C G+ L GH + CI G W+ P+C I C P I NG + +N +
Sbjct: 578 NYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHY 637
Query: 928 GSSVEYYC------LSQYQRVGPFLRKCL--DD--GRWSGEEPSC 962
GS V Y C ++ VG C DD G WSG P C
Sbjct: 638 GSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQC 682
Score = 221 bits (541), Expect = 8e-57
Identities = 186/664 (28%), Positives = 270/664 (40%), Gaps = 76/664 (11%)
Query: 352 TCGSPDKLLNTTI-LGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDG---FWSGAPPSCK 407
+C +P +N + + GS+I Y C +G+ L+G S C G W P C
Sbjct: 103 SCRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICD 162
Query: 408 YVNCGGLTPIEDGDVALIDNRTTH-GARALYSC------RENFTLVGNPERTC--GDE-- 456
+ CG I +GD + H G+ Y C R+ F LVG P C D+
Sbjct: 163 RIPCGLPPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQV 222
Query: 457 GIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGSL---ASYTCENGHILSGSTSVTCTL 513
GIW G AP+C+ PP V N + + SL + C+ G ++ G V C
Sbjct: 223 GIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQA 282
Query: 514 GGAWSGVPPSCKYVNCGTP--TIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCN 571
W PSC V C P +H + G ++CEP Y L GA + C
Sbjct: 283 LNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCT 341
Query: 572 RDGKWSYDIPSCELTSCPE--PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQ 629
G WS P+CE+ SC + ++ +G + + + + ++F C+ G +L G C
Sbjct: 342 PQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCV 401
Query: 630 QDGE---WSGDSPTCEYIDCGKLPTLPYG--TMELLNGTTHLGSVIQYSCT------TNY 678
G W+ P CE I C P +P G T + L G + Y+C T++
Sbjct: 402 LAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLE-VFPFGKAVNYTCDPHPDRGTSF 460
Query: 679 RLVGPVRRTCTEEFQ----WSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTS 734
L+G CT + Q WS +PRC + G+ ++ H L
Sbjct: 461 DLIGESTIRCTSDPQGNGVWSSPAPRC----------------GILGHCQAPDHFLFAKL 504
Query: 735 DNRDVGNTYRIGALVKYRCEKGYKVIGESLS-TCEDNGQWSGTTPTCQYVDCGNPGRIEN 793
+ + + IG +KY C Y G S TC DN WS C+ C P N
Sbjct: 505 KTQTNASDFPIGTSLKYECRPEY--YGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVN 562
Query: 794 GKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGT---WSLEPPICKEITCPDPSA 850
G V + ++ G+ Y C L G C +G WS +PPIC+ I C P
Sbjct: 563 GMVHVITDIQV-GSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPT 621
Query: 851 QIKAGSGLLVVTSTLSIGGEAHYQCERG------YNLKGHQTRTCISK----GQWNGTVP 900
I G + G Y+C G + L G + C S G W+G P
Sbjct: 622 -IANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAP 680
Query: 901 VCIPIDCRSPGNIENGKIVISNGSTLFGSS--VEYYCLSQYQRVGPFLRKCLDDGRWSGE 958
CI + +P N+ENG I++S+ +LF + VE+ C + GP KC +W E
Sbjct: 681 QCIXPNKCTPPNVENG-ILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPE 739
Query: 959 EPSC 962
PSC
Sbjct: 740 LPSC 743
Score = 206 bits (502), Expect = 4e-52
Identities = 178/668 (26%), Positives = 269/668 (40%), Gaps = 72/668 (10%)
Query: 353 CGSPDKLL----NTTILGNDYDVGSRIVYKC-PEGHMLLGDKSRHCKKDGFWSGAPPSCK 407
C +PD L T +D+ +G+ + Y+C PE + S C + WS CK
Sbjct: 943 CQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGR--PFSITCLDNLVWSSPKDVCK 1000
Query: 408 YVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTC---GDEGIWDGEAP 464
+C +G V +I + G+R YSC L+G+ C G+ W + P
Sbjct: 1001 RKSCKTPPDPVNGMVHVITDIXV-GSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPP 1059
Query: 465 RCLFDWCPDPPAVSNAS-VTVNGHKA--GSLASYTCENGHI------LSGSTSVTCTLG- 514
C C PP ++N ++ N GS+ +Y C G L G S+ CT
Sbjct: 1060 ICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSND 1119
Query: 515 ---GAWSGVPPSCKYVN-CGTPTIHKGSFVLINGTT-TYGSIAQFTCEPDYWLNGAEELV 569
G WSG P C N C P + G V N + + + +F C+P + + G +
Sbjct: 1120 DQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVK 1179
Query: 570 CNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAF--DYYVHSTINFHCEAGHKLIGEPNLV 627
C KW ++PSC P PE+ G + + ++ + + CE G+ L G +L
Sbjct: 1180 CQALNKWEPELPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLH 1239
Query: 628 CQQDGEWSGDSPTCEYIDCGK-LPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRR 686
C G+WS ++P C C L LP+G + L LG+ + + C +RL G
Sbjct: 1240 CTPQGDWSPEAPRCAVKSCDDFLGQLPHGRV-LFPLNLQLGAKVSFVCDEGFRLKGSSVS 1298
Query: 687 TCT---EEFQWSDSSPRCEEIRCSDP-IVAEKSIVSVTGNDRSHGHTLIRTSD-NRDVGN 741
C W++S P CE I C +P + D +G + T D + D G
Sbjct: 1299 HCVLVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGM 1358
Query: 742 TYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYV----DCGNPGRIENGKVT 797
T+ + RC S NG WS P C+ C P + T
Sbjct: 1359 TFNLIGESTIRCT----------SDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPT 1408
Query: 798 LPSNATFY--GATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAG 855
+P N + G + Y+C + + C EN WS C+ +C P
Sbjct: 1409 IPINDFEFPVGTSLNYECRPGY-FGKMFSISCLENLVWSSVEDNCRRKSCGPPPEPF--- 1464
Query: 856 SGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQ---WNGTVPVCIPIDCRSPGN 912
+G++ + + G +Y C G+ L G + TC+ G W+ P+C I C P
Sbjct: 1465 NGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPT 1524
Query: 913 IENGKIVISNGSTLF--GSSVEYYCLS------QYQRVGPFLRKCL--DD--GRWSGEEP 960
I NG SN T F G+ V Y C + ++ VG C DD G WS P
Sbjct: 1525 ISNGDF-YSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPP 1583
Query: 961 SCELATNE 968
C ++TN+
Sbjct: 1584 RC-ISTNK 1590
Score = 200 bits (488), Expect = 2e-50
Identities = 169/650 (26%), Positives = 256/650 (39%), Gaps = 79/650 (12%)
Query: 371 VGSRIVYKCPEGHMLLGDKSRHCKKDGF---WSGAPPSCKYVNCGGLTPIEDG-DVALID 426
+G+++ + C EG L G HC G W+ + P C+++ C I +G
Sbjct: 1278 LGAKVSFVCDEGFRLKGSSVSHCVLVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPS 1337
Query: 427 NRTTHGARALYSCREN------FTLVGNPERTCGDE----GIWDGEAPRCLFD----WCP 472
+G Y+C + F L+G C + G+W APRC C
Sbjct: 1338 GDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTSDPHGNGVWSSPAPRCELSVRAGHCK 1397
Query: 473 DPPAVSNASVTV--NGHK--AGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVN 528
P AS T+ N + G+ +Y C G+ S++C WS V +C+ +
Sbjct: 1398 TPEQFPFASPTIPINDFEFPVGTSLNYECRPGYF-GKMFSISCLENLVWSSVEDNCRRKS 1456
Query: 529 CGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGK---WSYDIPSCEL 585
CG P V IN T +GS ++C + L G+ C G W P CE+
Sbjct: 1457 CGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEI 1516
Query: 586 TSC-PEPEVPSGGYM--EAFDYYVHSTINFHCEAG------HKLIGEPNLVC----QQDG 632
SC P P + +G + ++ + + + C G +L+GE ++ C Q G
Sbjct: 1517 ISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVG 1576
Query: 633 EWSGDSPTCEYIDCGKLPTLPYGTMELLNGT-THLGSVIQYSCTTNYRLVGPVRRTCTEE 691
WS P C + P + N + L ++++ C + +VG C
Sbjct: 1577 VWSSPPPRCISTNKCTAPEVENAIRVPGNRSFFSLTEIVRFRCQPGFVMVGSHTVQCQTN 1636
Query: 692 FQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKY 751
+W P C + C P + HG + DN + G V Y
Sbjct: 1637 GRWGPKLPHCSRV-CQPP------------PEILHGEHTLSHQDN------FSPGQEVFY 1677
Query: 752 RCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGN-PGRIENGKVTLPSNATFYGATAF 810
CE Y + G + C G WS P C C + G++ +G+V LP N GA
Sbjct: 1678 SCEPSYDLRGAASLHCTPQGDWSPEAPRCTVKSCDDFLGQLPHGRVLLPLNLQL-GAKVS 1736
Query: 811 YQCDENWELEGVIRRMCQENG---TWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSI 867
+ CDE + L+G C G W+ P+C++I CP+P A I G +
Sbjct: 1737 FVCDEGFRLKGRSASHCVLAGMKALWNSSVPVCEQIFCPNPPA-ILNGRHTGTPFGDIPY 1795
Query: 868 GGEAHYQC----ERG--YNLKGHQTRTCIS----KGQWNGTVPVC---IPIDCRSPGNIE 914
G E Y C +RG +NL G + C S G W+ P C +P C P I+
Sbjct: 1796 GKEISYACDTHPDRGMTFNLIGESSIRCTSDRQGNGVWSSPAPRCELSVPAACPDPPKIQ 1855
Query: 915 NGKIVISNGST-LFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
NG + + S L G ++ Y C Y VG C D G WS + C+
Sbjct: 1856 NGHYIGGHVSLYLPGMTISYICDPGYLLVGKGFIFCTDQGIWSQLDHYCK 1905
Score = 196 bits (479), Expect = 3e-49
Identities = 185/688 (26%), Positives = 271/688 (39%), Gaps = 83/688 (12%)
Query: 345 ICQYLPPTCGSPDKLLNTTILGN---DYDVGSRIVYKC---PEGHM---LLGDKSRHCKK 395
+C+++ C +P +LN G D G I Y C P+ M L+G+ + C
Sbjct: 1315 VCEHI--FCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTS 1372
Query: 396 D----GFWSGAPPSCKY-VNCGGLT-----PIEDGDVALIDNRTTHGARALYSCRENFTL 445
D G WS P C+ V G P + + D G Y CR +
Sbjct: 1373 DPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDFEFPVGTSLNYECRPGY-- 1430
Query: 446 VGNP-ERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGH-KAGSLASYTCENGHIL 503
G +C + +W C C PP N V +N + GS +Y+C G L
Sbjct: 1431 FGKMFSISCLENLVWSSVEDNCRRKSCGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRL 1490
Query: 504 SGSTSVTCTLGG---AWSGVPPSCKYVNCGTP-TIHKGSFVLINGTTTY-GSIAQFTCE- 557
GS S TC + G W P C+ ++C P TI G F N T+ + G++ + C
Sbjct: 1491 IGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHT 1550
Query: 558 -PD----YWLNGAEELVC-NRD---GKWSYDIPSCELTS-CPEPEVPSGGYMEAFDYYVH 607
PD + L G + C ++D G WS P C T+ C PEV + + +
Sbjct: 1551 GPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRCISTNKCTAPEVENAIRVPGNRSFFS 1610
Query: 608 ST--INFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTH 665
T + F C+ G ++G + CQ +G W P C + C P + +G L +
Sbjct: 1611 LTEIVRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHCSRV-CQPPPEILHGEHTLSHQDNF 1669
Query: 666 L-GSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDR 724
G + YSC +Y L G CT + WS +PRC C D +
Sbjct: 1670 SPGQEVFYSCEPSYDLRGAASLHCTPQGDWSPEAPRCTVKSCDDFL-----------GQL 1718
Query: 725 SHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTCQ 781
HG L+ + ++GA V + C++G+++ G S S C G W+ + P C+
Sbjct: 1719 PHGRVLLPLN--------LQLGAKVSFVCDEGFRLKGRSASHCVLAGMKALWNSSVPVCE 1770
Query: 782 YVDCGNPGRIENGKVT-LPSNATFYGATAFYQCDEN------WELEGVIRRMC----QEN 830
+ C NP I NG+ T P YG Y CD + + L G C Q N
Sbjct: 1771 QIFCPNPPAILNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGESSIRCTSDRQGN 1830
Query: 831 GTWSLEPPICK---EITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTR 887
G WS P C+ CPDP +I+ G + S G Y C+ GY L G
Sbjct: 1831 GVWSSPAPRCELSVPAACPDPP-KIQNGHYIGGHVSLYLPGMTISYICDPGYLLVGKGFI 1889
Query: 888 TCISKGQWNGTVPVCIPIDCRSPGNIEN-GKIVISNGSTLFGSSVEYYCLSQYQRVGPFL 946
C +G W+ C ++C P + K + +G V C Y G
Sbjct: 1890 FCTDQGIWSQLDHYCKEVNCSFPLFMNGISKELEMKKVYHYGDYVTLKCEDGYTLEGSPW 1949
Query: 947 RKCLDDGRWSGEEPSCELATNEAVDSGT 974
+C D RW C ++A+ GT
Sbjct: 1950 SQCQADDRWDPPLAKCTSRAHDALIVGT 1977
Score = 196 bits (478), Expect = 4e-49
Identities = 176/677 (25%), Positives = 277/677 (40%), Gaps = 88/677 (12%)
Query: 345 ICQYLPPTCGSPDKLLNTTILGND---YDVGSRIVYKCPEGH------MLLGDKSRHCKK 395
IC +P CG P + N + + + GS + Y+C G L+G+ S +C
Sbjct: 160 ICDRIP--CGLPPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTS 217
Query: 396 D----GFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRTTHGARAL--YSCRENFTLVGNP 449
+ G WSG P C N +E+G + + DNR+ + + C+ F + G
Sbjct: 218 NDDQVGIWSGPAPQCIIPNKCTPPNVENG-ILVSDNRSLFSLNEVVEFRCQPGFVMKGPR 276
Query: 450 ERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTV---NGHKAGSLASYTCENGHILSGS 506
C W+ E P C C PP V +A T + G Y+CE G+ L G+
Sbjct: 277 RVKCQALNKWEPELPSCS-RVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGA 335
Query: 507 TSVTCTLGGAWSGVPPSCKYVNCGT--PTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNG 564
S+ CT G WS P+C+ +C + G VL G+ F C+ + L G
Sbjct: 336 ASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGR-VLFPVNLQLGAKVDFVCDEGFQLKG 394
Query: 565 AEELVC---NRDGKWSYDIPSCELTSCPEPEV-PSGGY----MEAFDY--YVHSTINFHC 614
+ C + W+ +P CE CP P V P+G + +E F + V+ T + H
Sbjct: 395 SSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHP 454
Query: 615 EAGHK--LIGEPNLVCQQD----GEWSGDSPTCEYIDCGKLPT-LPYGTMELLNGTTH-- 665
+ G LIGE + C D G WS +P C + + P + ++ +
Sbjct: 455 DRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFP 514
Query: 666 LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRS 725
+G+ ++Y C Y P TC + WS C+ C P D
Sbjct: 515 IGTSLKYECRPEY-YGRPFSITCLDNLVWSSPKDVCKRKSCKTP------------PDPV 561
Query: 726 HGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTCQY 782
+G + T D+ ++G+ + Y C G+++IG S + C +G WS P CQ
Sbjct: 562 NGMVHVIT----DI----QVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQR 613
Query: 783 VDCGNPGRIENGKVTLPSNATF-YGATAFYQCDEN------WELEGVIRRMCQEN----G 831
+ CG P I NG + F YG+ Y+C+ +EL G C N G
Sbjct: 614 IPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVG 673
Query: 832 TWSLEPPIC-KEITCPDPSAQIKAGSGLLVVT--STLSIGGEAHYQCERGYNLKGHQTRT 888
WS P C C P+ + +G+LV S S+ ++C+ G+ +KG +
Sbjct: 674 IWSGPAPQCIXPNKCTPPNVE----NGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVK 729
Query: 889 CISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLF-GSSVEYYCLSQYQRVGPFLR 947
C + +W +P C + C+ P ++ + + + G V Y C Y G
Sbjct: 730 CQALNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASM 788
Query: 948 KCLDDGRWSGEEPSCEL 964
+C G WS P+CE+
Sbjct: 789 RCTPQGDWSPAAPTCEV 805
Score = 196 bits (477), Expect = 5e-49
Identities = 181/674 (26%), Positives = 262/674 (38%), Gaps = 82/674 (12%)
Query: 353 CGSPDKLLNTTILGNDYDV---GSRIVYKC---PE---GHMLLGDKSRHCKKD----GFW 399
C SP + N G +V G + Y C P+ L+G+ + C D G W
Sbjct: 871 CPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVW 930
Query: 400 SGAPPSCKYV-NCGGLTPIEDGDVALIDNRTTH--GARALYSCRENFTLVGNP-ERTCGD 455
S P C + +C + N + G Y CR + G P TC D
Sbjct: 931 SSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEY--YGRPFSITCLD 988
Query: 456 EGIWDGEAPRCLFDWCPDPPAVSNASV-TVNGHKAGSLASYTCENGHILSGSTSVTCTLG 514
+W C C PP N V + GS +Y+C GH L G +S C L
Sbjct: 989 NLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIXVGSRINYSCTTGHRLIGHSSAECILS 1048
Query: 515 GA---WSGVPPSCKYVNCGTP-TIHKGSFVLINGTTT-YGSIAQFTCEPD------YWLN 563
G WS PP C+ + CG P TI G F+ N YGS+ + C + L
Sbjct: 1049 GNTAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELV 1108
Query: 564 GAEELVC--NRD--GKWSYDIPSCELTS-CPEPEVPSGGYMEAFD--YYVHSTINFHCEA 616
G + C N D G WS P C + + C P V +G + + ++ + F C+
Sbjct: 1109 GEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQP 1168
Query: 617 GHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHL-GSVIQYSCT 675
G + G + CQ +W + P+C + C P + +G + G + YSC
Sbjct: 1169 GFVMKGPRRVKCQALNKWEPELPSCSRV-CQPPPEILHGEHTPSHQDNFSPGQEVFYSCE 1227
Query: 676 TNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSD 735
Y L G CT + WS +PRC C D + HG L +
Sbjct: 1228 PGYDLRGAASLHCTPQGDWSPEAPRCAVKSCDDFL-----------GQLPHGRVLFPLN- 1275
Query: 736 NRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTCQYVDCGNPGRIE 792
++GA V + C++G+++ G S+S C G W+ + P C+++ C NP I
Sbjct: 1276 -------LQLGAKVSFVCDEGFRLKGSSVSHCVLVGMRSLWNNSVPVCEHIFCPNPPAIL 1328
Query: 793 NGKVT-LPSNATFYGATAFYQCDEN------WELEGVIRRMCQE----NGTWSLEPPICK 841
NG+ T PS YG Y CD + + L G C NG WS P C+
Sbjct: 1329 NGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTSDPHGNGVWSSPAPRCE 1388
Query: 842 EIT----CPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNG 897
C P A + + +G +Y+C GY K +C+ W+
Sbjct: 1389 LSVRAGHCKTPEQFPFASPTIPINDFEFPVGTSLNYECRPGYFGKMFSI-SCLENLVWSS 1447
Query: 898 TVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGR--- 954
C C P NG + I N T FGS+V Y C ++ +G CL G
Sbjct: 1448 VEDNCRRKSCGPPPEPFNGMVHI-NTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVT 1506
Query: 955 WSGEEPSCELATNE 968
W + P CE+ + E
Sbjct: 1507 WDKKAPICEIISCE 1520
Score = 187 bits (455), Expect = 2e-46
Identities = 173/666 (25%), Positives = 261/666 (39%), Gaps = 79/666 (11%)
Query: 353 CGSPDKLLNTTILGNDYDV---GSRIVYKC---PE---GHMLLGDKSRHCKKD----GFW 399
C SP + N G +V G + Y C P+ L+G+ + C D G W
Sbjct: 421 CPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVW 480
Query: 400 SGAPPSCKYV-NCGGLTPIEDGDVALIDNRTTH--GARALYSCRENFTLVGNP-ERTCGD 455
S P C + +C + N + G Y CR + G P TC D
Sbjct: 481 SSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEY--YGRPFSITCLD 538
Query: 456 EGIWDGEAPRCLFDWCPDPPAVSNASV-TVNGHKAGSLASYTCENGHILSGSTSVTCTLG 514
+W C C PP N V + + GS +Y+C GH L G +S C L
Sbjct: 539 NLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILS 598
Query: 515 GA---WSGVPPSCKYVNCGTP-TIHKGSFVLINGTTT-YGSIAQFTCEPD------YWLN 563
G WS PP C+ + CG P TI G F+ N YGS+ + C P + L
Sbjct: 599 GNAAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELV 658
Query: 564 GAEELVC--NRD--GKWSYDIPSCELTS-CPEPEVPSGGYMEAFD--YYVHSTINFHCEA 616
G + C N D G WS P C + C P V +G + + ++ + F C+
Sbjct: 659 GEPSIYCTSNDDQVGIWSGPAPQCIXPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQP 718
Query: 617 GHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHL-GSVIQYSCT 675
G + G + CQ +W + P+C + C P + + + G + YSC
Sbjct: 719 GFVMKGPRRVKCQALNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCE 777
Query: 676 TNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSD 735
Y L G CT + WS ++P CE C D + +G L +
Sbjct: 778 PGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDFM-----------GQLLNGRVLFPVN- 825
Query: 736 NRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTCQYVDCGNPGRIE 792
++GA V + C++G+++ G S S C G W+ + P C+ + C +P I
Sbjct: 826 -------LQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIP 878
Query: 793 NGKVT-LPSNATFYGATAFYQCD------ENWELEGVIRRMC----QENGTWSLEPPICK 841
NG+ T P +G Y CD +++L G C Q NG WS P C
Sbjct: 879 NGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCG 938
Query: 842 EI-TCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVP 900
+ C P + A S IG Y+C Y + TC+ W+
Sbjct: 939 ILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGRPFSI-TCLDNLVWSSPKD 997
Query: 901 VCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDG---RWSG 957
VC C++P + NG + + + GS + Y C + ++ +G +C+ G WS
Sbjct: 998 VCKRKSCKTPPDPVNGMVHVITDIXV-GSRINYSCTTGHRLIGHSSAECILSGNTAHWST 1056
Query: 958 EEPSCE 963
+ P C+
Sbjct: 1057 KPPICQ 1062
Score = 169 bits (411), Expect = 5e-41
Identities = 135/509 (26%), Positives = 209/509 (41%), Gaps = 59/509 (11%)
Query: 490 GSLASYTCENGHILSGST-SVTCTLGGAWSGVPPSCKYVNCGTPTIHKGSFVLINGTTTY 548
G+ +Y C G+ SG S+ C W+G C+ +C P V + +
Sbjct: 66 GTYLNYECRPGY--SGRPFSIICLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKGIQF 123
Query: 549 GSIAQFTCEPDYWLNGAEELVCNRDGK---WSYDIPSCELTSCP-EPEVPSGGYMEAF-- 602
GS +++C Y L G+ C G W + P C+ C P + +G ++
Sbjct: 124 GSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTITNGDFISTNRE 183
Query: 603 DYYVHSTINFHCEAGH------KLIGEPNLVC----QQDGEWSGDSPTCEYIDCGKLPTL 652
+++ S + + C G +L+GEP++ C Q G WSG +P C + P +
Sbjct: 184 NFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNV 243
Query: 653 PYGTMELLNGTTH-LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIV 711
G + N + L V+++ C + + GP R C +W P C + C P
Sbjct: 244 ENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRV-CQPP-- 300
Query: 712 AEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNG 771
D H R DN + G V Y CE GY + G + C G
Sbjct: 301 ----------PDVLHAERTQRDKDN------FSPGQEVFYSCEPGYDLRGAASMRCTPQG 344
Query: 772 QWSGTTPTCQYVDCGN-PGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQEN 830
WS PTC+ C + G++ NG+V P N GA + CDE ++L+G C
Sbjct: 345 DWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQL-GAKVDFVCDEGFQLKGSSASYCVLA 403
Query: 831 GT---WSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCE----RG--YNL 881
G W+ P+C++I CP P I G G +Y C+ RG ++L
Sbjct: 404 GMESLWNSSVPVCEQIFCPSPPV-IPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDL 462
Query: 882 KGHQTRTCIS----KGQWNGTVPVC-IPIDCRSPGNIENGKIVISNGSTLF--GSSVEYY 934
G T C S G W+ P C I C++P + K+ ++ F G+S++Y
Sbjct: 463 IGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYE 522
Query: 935 CLSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
C +Y PF CLD+ WS + C+
Sbjct: 523 CRPEYYG-RPFSITCLDNLVWSSPKDVCK 550
Score = 101 bits (243), Expect = 1e-20
Identities = 80/316 (25%), Positives = 124/316 (39%), Gaps = 42/316 (13%)
Query: 666 LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRS 725
+G+ + Y C Y P C + W+ + RC C +P +V V
Sbjct: 65 IGTYLNYECRPGYS-GRPFSIICLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKG--- 120
Query: 726 HGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTCQY 782
+ G+ +KY C KGY++IG S +TC +G W TP C
Sbjct: 121 -----------------IQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDR 163
Query: 783 VDCGNPGRIENGKVTLPSNATF-YGATAFYQCDEN------WELEGVIRRMCQEN----G 831
+ CG P I NG + F YG+ Y+C+ +EL G C N G
Sbjct: 164 IPCGLPPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVG 223
Query: 832 TWSLEPPICKEITCPDPSAQIKAGSGLLVV--TSTLSIGGEAHYQCERGYNLKGHQTRTC 889
WS P C P+ +G+LV S S+ ++C+ G+ +KG + C
Sbjct: 224 IWSGPAPQC---IIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKC 280
Query: 890 ISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLF-GSSVEYYCLSQYQRVGPFLRK 948
+ +W +P C + C+ P ++ + + + G V Y C Y G +
Sbjct: 281 QALNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMR 339
Query: 949 CLDDGRWSGEEPSCEL 964
C G WS P+CE+
Sbjct: 340 CTPQGDWSPAAPTCEV 355
Score = 44.0 bits (99), Expect = 0.003
Identities = 17/42 (40%), Positives = 24/42 (57%)
Query: 17 NEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
+++N G Y C+ GY+L GA CT +GDW+ E P C
Sbjct: 1212 HQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGDWSPEAPRC 1253
Score = 42.7 bits (96), Expect = 0.007
Identities = 18/57 (31%), Positives = 28/57 (49%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C P + ++ +++N G Y C+ Y+L GA CT +GDW+ E P C
Sbjct: 1650 CQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCTPQGDWSPEAPRC 1706
Score = 42.3 bits (95), Expect = 0.009
Identities = 19/57 (33%), Positives = 28/57 (49%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C P +A + +++N G Y C+ GY+L GA CT +GDW+ P C
Sbjct: 297 CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTC 353
Score = 42.3 bits (95), Expect = 0.009
Identities = 19/57 (33%), Positives = 28/57 (49%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C P +A + +++N G Y C+ GY+L GA CT +GDW+ P C
Sbjct: 747 CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTC 803
Score = 37.9 bits (84), Expect = 0.20
Identities = 20/60 (33%), Positives = 27/60 (45%), Gaps = 5/60 (8%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGD---WTLEPPFC 58
C P P N V + + I G+ Y C G+ L G EC L G+ W+ +PP C
Sbjct: 1004 CKTPPDPVNGMVHVITD--IXVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPIC 1061
Score = 37.5 bits (83), Expect = 0.26
Identities = 20/60 (33%), Positives = 27/60 (45%), Gaps = 5/60 (8%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGD---WTLEPPFC 58
C +P P N V + + I G+ Y C +GY L G+ C + GD W E P C
Sbjct: 104 CRNPPDPVNGMVHVI--KGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPIC 161
Score = 37.5 bits (83), Expect = 0.26
Identities = 20/60 (33%), Positives = 27/60 (45%), Gaps = 5/60 (8%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGD---WTLEPPFC 58
C P P N V + + I G+ Y C G+ L G EC L G+ W+ +PP C
Sbjct: 554 CKTPPDPVNGMVHVITD--IQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPIC 611
Score = 37.5 bits (83), Expect = 0.26
Identities = 19/60 (31%), Positives = 27/60 (45%), Gaps = 5/60 (8%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGD---WTLEPPFC 58
CG P P N V I + G+ Y C+EG+ L G+ C + G+ W + P C
Sbjct: 1457 CGPPPEPFNGMVHINTDTQF--GSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPIC 1514
>L17418-1|AAB60695.1| 2489|Homo sapiens complement receptor 1 protein.
Length = 2489
Score = 234 bits (573), Expect = 1e-60
Identities = 194/665 (29%), Positives = 275/665 (41%), Gaps = 78/665 (11%)
Query: 352 TCGSPDKLLNTTI-LGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDG---FWSGAPPSCK 407
+C +P +N + + D VGSRI Y C GH L+G S C G WS PP C+
Sbjct: 1003 SCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQ 1062
Query: 408 YVNCGGLTPIEDGDVALIDNRTTH-GARALYSC------RENFTLVGNPERTC--GDE-- 456
+ CG I +GD + H G+ Y C R+ F LVG P C D+
Sbjct: 1063 RIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQV 1122
Query: 457 GIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGSL---ASYTCENGHILSGSTSVTCTL 513
GIW G AP+C+ PP V N + + SL + C+ G ++ G V C
Sbjct: 1123 GIWSGPAPQCIXPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQA 1182
Query: 514 GGAWSGVPPSCKYVNCGTP--TIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCN 571
W PSC V C P +H + G ++CEP Y L GA + C
Sbjct: 1183 LNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCT 1241
Query: 572 RDGKWSYDIPSCELTSCPE--PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQ 629
G WS P+CE+ SC + ++ +G + + + + ++F C+ G +L G C
Sbjct: 1242 PQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCV 1301
Query: 630 QDGE---WSGDSPTCEYIDCGKLPTLPYG--TMELLNGTTHLGSVIQYSCT------TNY 678
G W+ P CE I C P +P G T + L G + Y+C T++
Sbjct: 1302 LAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLE-VFPFGKAVNYTCDPHPDRGTSF 1360
Query: 679 RLVGPVRRTCTEEFQ----WSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTS 734
L+G CT + Q WS +PRC + G+ ++ H L
Sbjct: 1361 DLIGESTIRCTSDPQGNGVWSSPAPRC----------------GILGHCQAPDHFLFAKL 1404
Query: 735 DNRDVGNTYRIGALVKYRCEKGYKVIGESLS-TCEDNGQWSGTTPTCQYVDCGNPGRIEN 793
+ + + IG +KY C Y G S TC DN WS C+ C P N
Sbjct: 1405 KTQTNASDFPIGTSLKYECRPEY--YGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVN 1462
Query: 794 GKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGT---WSLEPPICKEITCPDPSA 850
G V + ++ G+ Y C L G C +G WS +PPIC+ I C P
Sbjct: 1463 GMVHVITDIXV-GSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPCGLPPT 1521
Query: 851 QIKAGSGLLVVTSTLSIGGEAHYQCERG------YNLKGHQTRTCISK----GQWNGTVP 900
I G + G Y+C G + L G + C S G W+G P
Sbjct: 1522 -IANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAP 1580
Query: 901 VC-IPIDCRSPGNIENGKIVISNGSTLFGSS--VEYYCLSQYQRVGPFLRKCLDDGRWSG 957
C IP C +P N+ENG I++S+ +LF + VE+ C + GP KC +W
Sbjct: 1581 QCIIPNKC-TPPNVENG-ILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEP 1638
Query: 958 EEPSC 962
E PSC
Sbjct: 1639 ELPSC 1643
Score = 234 bits (572), Expect = 1e-60
Identities = 192/664 (28%), Positives = 274/664 (41%), Gaps = 76/664 (11%)
Query: 352 TCGSPDKLLNTTI-LGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDG---FWSGAPPSCK 407
+C +P +N + + D VGSRI Y C GH L+G S C G WS PP C+
Sbjct: 553 SCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQ 612
Query: 408 YVNCGGLTPIEDGDVALIDNRTTH-GARALYSC------RENFTLVGNPERTC--GDE-- 456
+ CG I +GD + H G+ Y C R+ F LVG P C D+
Sbjct: 613 RIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQV 672
Query: 457 GIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGSL---ASYTCENGHILSGSTSVTCTL 513
GIW G AP+C+ PP V N + + SL + C+ G ++ G V C
Sbjct: 673 GIWSGPAPQCIXPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQA 732
Query: 514 GGAWSGVPPSCKYVNCGTP--TIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCN 571
W PSC V C P +H + G ++CEP Y L GA + C
Sbjct: 733 LNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCT 791
Query: 572 RDGKWSYDIPSCELTSCPE--PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQ 629
G WS P+CE+ SC + ++ +G + + + + ++F C+ G +L G C
Sbjct: 792 PQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCV 851
Query: 630 QDGE---WSGDSPTCEYIDCGKLPTLPYG--TMELLNGTTHLGSVIQYSCT------TNY 678
G W+ P CE I C P +P G T + L G + Y+C T++
Sbjct: 852 LAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLE-VFPFGKTVNYTCDPHPDRGTSF 910
Query: 679 RLVGPVRRTCTEEFQ----WSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTS 734
L+G CT + Q WS +PRC + G+ ++ H L
Sbjct: 911 DLIGESTIRCTSDPQGNGVWSSPAPRC----------------GILGHCQAPDHFLFAKL 954
Query: 735 DNRDVGNTYRIGALVKYRCEKGYKVIGESLS-TCEDNGQWSGTTPTCQYVDCGNPGRIEN 793
+ + + IG +KY C Y G S TC DN WS C+ C P N
Sbjct: 955 KTQTNASDFPIGTSLKYECRPEY--YGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVN 1012
Query: 794 GKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGT---WSLEPPICKEITCPDPSA 850
G V + ++ G+ Y C L G C +G WS +PPIC+ I C P
Sbjct: 1013 GMVHVITDIQV-GSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPT 1071
Query: 851 QIKAGSGLLVVTSTLSIGGEAHYQCERG------YNLKGHQTRTCISK----GQWNGTVP 900
I G + G Y+C G + L G + C S G W+G P
Sbjct: 1072 -IANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAP 1130
Query: 901 VCIPIDCRSPGNIENGKIVISNGSTLFGSS--VEYYCLSQYQRVGPFLRKCLDDGRWSGE 958
CI + +P N+ENG I++S+ +LF + VE+ C + GP KC +W E
Sbjct: 1131 QCIXPNKCTPPNVENG-ILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPE 1189
Query: 959 EPSC 962
PSC
Sbjct: 1190 LPSC 1193
Score = 227 bits (555), Expect = 2e-58
Identities = 188/662 (28%), Positives = 274/662 (41%), Gaps = 69/662 (10%)
Query: 352 TCGSPDKLLNTTI-LGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDG---FWSGAPPSCK 407
+C +P +N + + D VGSRI Y C GH L+G S C G WS PP C+
Sbjct: 1453 SCKTPPDPVNGMVHVITDIXVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQ 1512
Query: 408 YVNCGGLTPIEDGDVALIDNRTTH-GARALYSC------RENFTLVGNPERTC--GDE-- 456
+ CG I +GD + H G+ Y C R+ F LVG P C D+
Sbjct: 1513 RIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQV 1572
Query: 457 GIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGSL---ASYTCENGHILSGSTSVTCTL 513
GIW G AP+C+ PP V N + + SL + C+ G ++ G V C
Sbjct: 1573 GIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQA 1632
Query: 514 GGAWSGVPPSCKYVNCGTPTIHKGSFVLINGTT-TYGSIAQFTCEPDYWLNGAEELVCNR 572
W PSC V P I G + + G ++CEP Y L GA L C
Sbjct: 1633 LNKWEPELPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTP 1692
Query: 573 DGKWSYDIPSCELTSCPE--PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQ 630
G WS + P C + SC + ++P G + + + + ++F C+ G +L G C
Sbjct: 1693 QGDWSPEAPRCAVKSCDDFLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCVL 1752
Query: 631 DGE---WSGDSPTCEYIDCGKLPTLPYGT-MELLNGTTHLGSVIQYSCTTN------YRL 680
G W+ P CE+I C P + G +G G I Y+C + + L
Sbjct: 1753 VGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNL 1812
Query: 681 VGPVRRTCTEEFQ----WSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDN 736
+G CT + WS +PRCE ++ ++ T I +D
Sbjct: 1813 IGESTIRCTSDPHGNGVWSSPAPRCE--------LSVRAGHCKTPEQFPFASPTIPINDF 1864
Query: 737 RDVGNTYRIGALVKYRCEKGYKVIGESLS-TCEDNGQWSGTTPTCQYVDCGNPGRIENGK 795
+ +G + Y C GY G+ S +C +N WS C+ CG P NG
Sbjct: 1865 E-----FPVGTSLNYECRPGY--FGKMFSISCLENLVWSSVEDNCRRKSCGPPPEPFNGM 1917
Query: 796 VTLPSNATFYGATAFYQCDENWELEGVIRRMCQENG---TWSLEPPICKEITCPDPSAQI 852
V + ++ T +G+T Y C+E + L G C +G TW + PIC+ I+C +P I
Sbjct: 1918 VHINTD-TQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISC-EPPPTI 1975
Query: 853 KAGSGLLVVTSTLSIGGEAHYQCERG------YNLKGHQTRTCISK----GQWNGTVPVC 902
G ++ G YQC G + L G ++ C SK G W+ P C
Sbjct: 1976 SNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRC 2035
Query: 903 IPID-CRSPGNIENGKIVISNGSTL-FGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEP 960
I + C +P +EN V N S V + C + VG +C +GRW + P
Sbjct: 2036 ISTNKCTAP-EVENAIRVPGNRSFFSLTEIVRFRCQPGFVMVGSHTVQCQTNGRWGPKLP 2094
Query: 961 SC 962
C
Sbjct: 2095 HC 2096
Score = 224 bits (547), Expect = 2e-57
Identities = 175/645 (27%), Positives = 261/645 (40%), Gaps = 74/645 (11%)
Query: 368 DYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDN 427
++ +G+ + Y+C G+ S C K+ W+GA C+ +C +G V +I
Sbjct: 62 EFPIGTYLNYECRPGYSGR-PFSIICLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKG 120
Query: 428 RTTHGARALYSCRENFTLVGNPERTC---GDEGIWDGEAPRCLFDWCPDPPAVSNA---S 481
G++ YSC + + L+G+ TC GD IWD E P C C PP ++N S
Sbjct: 121 -IQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTITNGDFIS 179
Query: 482 VTVNGHKAGSLASYTCENG------HILSGSTSVTCTLG----GAWSGVPPSCKYVN-CG 530
GS+ +Y C G L G S+ CT G WSG P C N C
Sbjct: 180 TNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCT 239
Query: 531 TPTIHKGSFVLINGTT-TYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCP 589
P + G V N + + + +F C+P + + G + C KW ++PSC P
Sbjct: 240 PPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQP 299
Query: 590 EPEV--PSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCG 647
P+V + ++ + + CE G+ L G ++ C G+WS +PTCE C
Sbjct: 300 PPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCD 359
Query: 648 KLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCT---EEFQWSDSSPRCEEI 704
L LG+ + + C ++L G C E W+ S P CE+I
Sbjct: 360 DFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQI 419
Query: 705 RCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCE------KGYK 758
C P V N R G L + G V Y C+ +
Sbjct: 420 FCPSP--------PVIPNGRHTGKPL----------EVFPFGKAVNYTCDPHPDRGTSFD 461
Query: 759 VIGESLSTC----EDNGQWSGTTPTCQYV-DCGNPGRIENGKVTLPSNATFY--GATAFY 811
+IGES C + NG WS P C + C P K+ +NA+ + G + Y
Sbjct: 462 LIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKY 521
Query: 812 QCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEA 871
+C + C +N WS +CK +C P + +G++ V + + +G
Sbjct: 522 ECRPEY-YGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPV---NGMVHVITDIQVGSRI 577
Query: 872 HYQCERGYNLKGHQTRTCISKG---QWNGTVPVCIPIDCRSPGNIENGKIVISNGSTL-F 927
+Y C G+ L GH + CI G W+ P+C I C P I NG + +N +
Sbjct: 578 NYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHY 637
Query: 928 GSSVEYYC------LSQYQRVGPFLRKCL--DD--GRWSGEEPSC 962
GS V Y C ++ VG C DD G WSG P C
Sbjct: 638 GSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQC 682
Score = 221 bits (541), Expect = 8e-57
Identities = 186/664 (28%), Positives = 270/664 (40%), Gaps = 76/664 (11%)
Query: 352 TCGSPDKLLNTTI-LGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDG---FWSGAPPSCK 407
+C +P +N + + GS+I Y C +G+ L+G S C G W P C
Sbjct: 103 SCRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICD 162
Query: 408 YVNCGGLTPIEDGDVALIDNRTTH-GARALYSC------RENFTLVGNPERTC--GDE-- 456
+ CG I +GD + H G+ Y C R+ F LVG P C D+
Sbjct: 163 RIPCGLPPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQV 222
Query: 457 GIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGSL---ASYTCENGHILSGSTSVTCTL 513
GIW G AP+C+ PP V N + + SL + C+ G ++ G V C
Sbjct: 223 GIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQA 282
Query: 514 GGAWSGVPPSCKYVNCGTP--TIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCN 571
W PSC V C P +H + G ++CEP Y L GA + C
Sbjct: 283 LNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCT 341
Query: 572 RDGKWSYDIPSCELTSCPE--PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQ 629
G WS P+CE+ SC + ++ +G + + + + ++F C+ G +L G C
Sbjct: 342 PQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCV 401
Query: 630 QDGE---WSGDSPTCEYIDCGKLPTLPYG--TMELLNGTTHLGSVIQYSCT------TNY 678
G W+ P CE I C P +P G T + L G + Y+C T++
Sbjct: 402 LAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLE-VFPFGKAVNYTCDPHPDRGTSF 460
Query: 679 RLVGPVRRTCTEEFQ----WSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTS 734
L+G CT + Q WS +PRC + G+ ++ H L
Sbjct: 461 DLIGESTIRCTSDPQGNGVWSSPAPRC----------------GILGHCQAPDHFLFAKL 504
Query: 735 DNRDVGNTYRIGALVKYRCEKGYKVIGESLS-TCEDNGQWSGTTPTCQYVDCGNPGRIEN 793
+ + + IG +KY C Y G S TC DN WS C+ C P N
Sbjct: 505 KTQTNASDFPIGTSLKYECRPEY--YGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVN 562
Query: 794 GKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGT---WSLEPPICKEITCPDPSA 850
G V + ++ G+ Y C L G C +G WS +PPIC+ I C P
Sbjct: 563 GMVHVITDIQV-GSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPT 621
Query: 851 QIKAGSGLLVVTSTLSIGGEAHYQCERG------YNLKGHQTRTCISK----GQWNGTVP 900
I G + G Y+C G + L G + C S G W+G P
Sbjct: 622 -IANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAP 680
Query: 901 VCIPIDCRSPGNIENGKIVISNGSTLFGSS--VEYYCLSQYQRVGPFLRKCLDDGRWSGE 958
CI + +P N+ENG I++S+ +LF + VE+ C + GP KC +W E
Sbjct: 681 QCIXPNKCTPPNVENG-ILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPE 739
Query: 959 EPSC 962
PSC
Sbjct: 740 LPSC 743
Score = 206 bits (502), Expect = 4e-52
Identities = 178/668 (26%), Positives = 269/668 (40%), Gaps = 72/668 (10%)
Query: 353 CGSPDKLL----NTTILGNDYDVGSRIVYKC-PEGHMLLGDKSRHCKKDGFWSGAPPSCK 407
C +PD L T +D+ +G+ + Y+C PE + S C + WS CK
Sbjct: 1393 CQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGR--PFSITCLDNLVWSSPKDVCK 1450
Query: 408 YVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTC---GDEGIWDGEAP 464
+C +G V +I + G+R YSC L+G+ C G+ W + P
Sbjct: 1451 RKSCKTPPDPVNGMVHVITDIXV-GSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPP 1509
Query: 465 RCLFDWCPDPPAVSNAS-VTVNGHKA--GSLASYTCENGHI------LSGSTSVTCTLG- 514
C C PP ++N ++ N GS+ +Y C G L G S+ CT
Sbjct: 1510 ICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSND 1569
Query: 515 ---GAWSGVPPSCKYVN-CGTPTIHKGSFVLINGTT-TYGSIAQFTCEPDYWLNGAEELV 569
G WSG P C N C P + G V N + + + +F C+P + + G +
Sbjct: 1570 DQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVK 1629
Query: 570 CNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAF--DYYVHSTINFHCEAGHKLIGEPNLV 627
C KW ++PSC P PE+ G + + ++ + + CE G+ L G +L
Sbjct: 1630 CQALNKWEPELPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLH 1689
Query: 628 CQQDGEWSGDSPTCEYIDCGK-LPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRR 686
C G+WS ++P C C L LP+G + L LG+ + + C +RL G
Sbjct: 1690 CTPQGDWSPEAPRCAVKSCDDFLGQLPHGRV-LFPLNLQLGAKVSFVCDEGFRLKGSSVS 1748
Query: 687 TCT---EEFQWSDSSPRCEEIRCSDP-IVAEKSIVSVTGNDRSHGHTLIRTSD-NRDVGN 741
C W++S P CE I C +P + D +G + T D + D G
Sbjct: 1749 HCVLVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGM 1808
Query: 742 TYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYV----DCGNPGRIENGKVT 797
T+ + RC S NG WS P C+ C P + T
Sbjct: 1809 TFNLIGESTIRCT----------SDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPT 1858
Query: 798 LPSNATFY--GATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAG 855
+P N + G + Y+C + + C EN WS C+ +C P
Sbjct: 1859 IPINDFEFPVGTSLNYECRPGY-FGKMFSISCLENLVWSSVEDNCRRKSCGPPPEPF--- 1914
Query: 856 SGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQ---WNGTVPVCIPIDCRSPGN 912
+G++ + + G +Y C G+ L G + TC+ G W+ P+C I C P
Sbjct: 1915 NGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPT 1974
Query: 913 IENGKIVISNGSTLF--GSSVEYYCLS------QYQRVGPFLRKCL--DD--GRWSGEEP 960
I NG SN T F G+ V Y C + ++ VG C DD G WS P
Sbjct: 1975 ISNGDF-YSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPP 2033
Query: 961 SCELATNE 968
C ++TN+
Sbjct: 2034 RC-ISTNK 2040
Score = 200 bits (488), Expect = 2e-50
Identities = 169/650 (26%), Positives = 256/650 (39%), Gaps = 79/650 (12%)
Query: 371 VGSRIVYKCPEGHMLLGDKSRHCKKDGF---WSGAPPSCKYVNCGGLTPIEDG-DVALID 426
+G+++ + C EG L G HC G W+ + P C+++ C I +G
Sbjct: 1728 LGAKVSFVCDEGFRLKGSSVSHCVLVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPS 1787
Query: 427 NRTTHGARALYSCREN------FTLVGNPERTCGDE----GIWDGEAPRCLFD----WCP 472
+G Y+C + F L+G C + G+W APRC C
Sbjct: 1788 GDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTSDPHGNGVWSSPAPRCELSVRAGHCK 1847
Query: 473 DPPAVSNASVTV--NGHK--AGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVN 528
P AS T+ N + G+ +Y C G+ S++C WS V +C+ +
Sbjct: 1848 TPEQFPFASPTIPINDFEFPVGTSLNYECRPGYF-GKMFSISCLENLVWSSVEDNCRRKS 1906
Query: 529 CGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGK---WSYDIPSCEL 585
CG P V IN T +GS ++C + L G+ C G W P CE+
Sbjct: 1907 CGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEI 1966
Query: 586 TSC-PEPEVPSGGYM--EAFDYYVHSTINFHCEAG------HKLIGEPNLVC----QQDG 632
SC P P + +G + ++ + + + C G +L+GE ++ C Q G
Sbjct: 1967 ISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVG 2026
Query: 633 EWSGDSPTCEYIDCGKLPTLPYGTMELLNGT-THLGSVIQYSCTTNYRLVGPVRRTCTEE 691
WS P C + P + N + L ++++ C + +VG C
Sbjct: 2027 VWSSPPPRCISTNKCTAPEVENAIRVPGNRSFFSLTEIVRFRCQPGFVMVGSHTVQCQTN 2086
Query: 692 FQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKY 751
+W P C + C P + HG + DN + G V Y
Sbjct: 2087 GRWGPKLPHCSRV-CQPP------------PEILHGEHTLSHQDN------FSPGQEVFY 2127
Query: 752 RCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGN-PGRIENGKVTLPSNATFYGATAF 810
CE Y + G + C G WS P C C + G++ +G+V LP N GA
Sbjct: 2128 SCEPSYDLRGAASLHCTPQGDWSPEAPRCTVKSCDDFLGQLPHGRVLLPLNLQL-GAKVS 2186
Query: 811 YQCDENWELEGVIRRMCQENG---TWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSI 867
+ CDE + L+G C G W+ P+C++I CP+P A I G +
Sbjct: 2187 FVCDEGFRLKGRSASHCVLAGMKALWNSSVPVCEQIFCPNPPA-ILNGRHTGTPFGDIPY 2245
Query: 868 GGEAHYQC----ERG--YNLKGHQTRTCIS----KGQWNGTVPVC---IPIDCRSPGNIE 914
G E Y C +RG +NL G + C S G W+ P C +P C P I+
Sbjct: 2246 GKEISYACDTHPDRGMTFNLIGESSIRCTSDRQGNGVWSSPAPRCELSVPAACPDPPKIQ 2305
Query: 915 NGKIVISNGST-LFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
NG + + S L G ++ Y C Y VG C D G WS + C+
Sbjct: 2306 NGHYIGGHVSLYLPGMTISYICDPGYLLVGKGFIFCTDQGIWSQLDHYCK 2355
Score = 199 bits (485), Expect = 5e-50
Identities = 176/679 (25%), Positives = 277/679 (40%), Gaps = 92/679 (13%)
Query: 345 ICQYLPPTCGSPDKLLNTTILGND---YDVGSRIVYKCPEGH------MLLGDKSRHCKK 395
ICQ +P CG P + N + + + GS + Y+C G L+G+ S +C
Sbjct: 610 ICQRIP--CGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTS 667
Query: 396 D----GFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRTTHGARAL--YSCRENFTLVGNP 449
+ G WSG P C N +E+G + + DNR+ + + C+ F + G
Sbjct: 668 NDDQVGIWSGPAPQCIXPNKCTPPNVENG-ILVSDNRSLFSLNEVVEFRCQPGFVMKGPR 726
Query: 450 ERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTV---NGHKAGSLASYTCENGHILSGS 506
C W+ E P C C PP V +A T + G Y+CE G+ L G+
Sbjct: 727 RVKCQALNKWEPELPSCS-RVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGA 785
Query: 507 TSVTCTLGGAWSGVPPSCKYVNCGT--PTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNG 564
S+ CT G WS P+C+ +C + G VL G+ F C+ + L G
Sbjct: 786 ASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGR-VLFPVNLQLGAKVDFVCDEGFQLKG 844
Query: 565 AEELVC---NRDGKWSYDIPSCELTSCPEPEV-PSGGY----MEAFDYYVHSTINFHCE- 615
+ C + W+ +P CE CP P V P+G + +E F + T+N+ C+
Sbjct: 845 SSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPF--GKTVNYTCDP 902
Query: 616 -----AGHKLIGEPNLVCQQD----GEWSGDSPTCEYIDCGKLPT-LPYGTMELLNGTTH 665
LIGE + C D G WS +P C + + P + ++ +
Sbjct: 903 HPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASD 962
Query: 666 --LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGND 723
+G+ ++Y C Y P TC + WS C+ C P D
Sbjct: 963 FPIGTSLKYECRPEY-YGRPFSITCLDNLVWSSPKDVCKRKSCKTP------------PD 1009
Query: 724 RSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTC 780
+G + T D+ ++G+ + Y C G+++IG S + C +G WS P C
Sbjct: 1010 PVNGMVHVIT----DI----QVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPIC 1061
Query: 781 QYVDCGNPGRIENGKVTLPSNATF-YGATAFYQCDEN------WELEGVIRRMCQEN--- 830
Q + CG P I NG + F YG+ Y+C+ +EL G C N
Sbjct: 1062 QRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQ 1121
Query: 831 -GTWSLEPPIC-KEITCPDPSAQIKAGSGLLVVT--STLSIGGEAHYQCERGYNLKGHQT 886
G WS P C C P+ + +G+LV S S+ ++C+ G+ +KG +
Sbjct: 1122 VGIWSGPAPQCIXPNKCTPPNVE----NGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRR 1177
Query: 887 RTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLF-GSSVEYYCLSQYQRVGPF 945
C + +W +P C + C+ P ++ + + + G V Y C Y G
Sbjct: 1178 VKCQALNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAA 1236
Query: 946 LRKCLDDGRWSGEEPSCEL 964
+C G WS P+CE+
Sbjct: 1237 SMRCTPQGDWSPAAPTCEV 1255
Score = 196 bits (479), Expect = 3e-49
Identities = 185/688 (26%), Positives = 271/688 (39%), Gaps = 83/688 (12%)
Query: 345 ICQYLPPTCGSPDKLLNTTILGN---DYDVGSRIVYKC---PEGHM---LLGDKSRHCKK 395
+C+++ C +P +LN G D G I Y C P+ M L+G+ + C
Sbjct: 1765 VCEHI--FCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTS 1822
Query: 396 D----GFWSGAPPSCKY-VNCGGLT-----PIEDGDVALIDNRTTHGARALYSCRENFTL 445
D G WS P C+ V G P + + D G Y CR +
Sbjct: 1823 DPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDFEFPVGTSLNYECRPGY-- 1880
Query: 446 VGNP-ERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGH-KAGSLASYTCENGHIL 503
G +C + +W C C PP N V +N + GS +Y+C G L
Sbjct: 1881 FGKMFSISCLENLVWSSVEDNCRRKSCGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRL 1940
Query: 504 SGSTSVTCTLGG---AWSGVPPSCKYVNCGTP-TIHKGSFVLINGTTTY-GSIAQFTCE- 557
GS S TC + G W P C+ ++C P TI G F N T+ + G++ + C
Sbjct: 1941 IGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHT 2000
Query: 558 -PD----YWLNGAEELVC-NRD---GKWSYDIPSCELTS-CPEPEVPSGGYMEAFDYYVH 607
PD + L G + C ++D G WS P C T+ C PEV + + +
Sbjct: 2001 GPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRCISTNKCTAPEVENAIRVPGNRSFFS 2060
Query: 608 ST--INFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTH 665
T + F C+ G ++G + CQ +G W P C + C P + +G L +
Sbjct: 2061 LTEIVRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHCSRV-CQPPPEILHGEHTLSHQDNF 2119
Query: 666 L-GSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDR 724
G + YSC +Y L G CT + WS +PRC C D +
Sbjct: 2120 SPGQEVFYSCEPSYDLRGAASLHCTPQGDWSPEAPRCTVKSCDDFL-----------GQL 2168
Query: 725 SHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTCQ 781
HG L+ + ++GA V + C++G+++ G S S C G W+ + P C+
Sbjct: 2169 PHGRVLLPLN--------LQLGAKVSFVCDEGFRLKGRSASHCVLAGMKALWNSSVPVCE 2220
Query: 782 YVDCGNPGRIENGKVT-LPSNATFYGATAFYQCDEN------WELEGVIRRMC----QEN 830
+ C NP I NG+ T P YG Y CD + + L G C Q N
Sbjct: 2221 QIFCPNPPAILNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGESSIRCTSDRQGN 2280
Query: 831 GTWSLEPPICK---EITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTR 887
G WS P C+ CPDP +I+ G + S G Y C+ GY L G
Sbjct: 2281 GVWSSPAPRCELSVPAACPDPP-KIQNGHYIGGHVSLYLPGMTISYICDPGYLLVGKGFI 2339
Query: 888 TCISKGQWNGTVPVCIPIDCRSPGNIEN-GKIVISNGSTLFGSSVEYYCLSQYQRVGPFL 946
C +G W+ C ++C P + K + +G V C Y G
Sbjct: 2340 FCTDQGIWSQLDHYCKEVNCSFPLFMNGISKELEMKKVYHYGDYVTLKCEDGYTLEGSPW 2399
Query: 947 RKCLDDGRWSGEEPSCELATNEAVDSGT 974
+C D RW C ++A+ GT
Sbjct: 2400 SQCQADDRWDPPLAKCTSRAHDALIVGT 2427
Score = 196 bits (478), Expect = 4e-49
Identities = 176/677 (25%), Positives = 277/677 (40%), Gaps = 88/677 (12%)
Query: 345 ICQYLPPTCGSPDKLLNTTILGND---YDVGSRIVYKCPEGH------MLLGDKSRHCKK 395
IC +P CG P + N + + + GS + Y+C G L+G+ S +C
Sbjct: 160 ICDRIP--CGLPPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTS 217
Query: 396 D----GFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRTTHGARAL--YSCRENFTLVGNP 449
+ G WSG P C N +E+G + + DNR+ + + C+ F + G
Sbjct: 218 NDDQVGIWSGPAPQCIIPNKCTPPNVENG-ILVSDNRSLFSLNEVVEFRCQPGFVMKGPR 276
Query: 450 ERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTV---NGHKAGSLASYTCENGHILSGS 506
C W+ E P C C PP V +A T + G Y+CE G+ L G+
Sbjct: 277 RVKCQALNKWEPELPSCS-RVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGA 335
Query: 507 TSVTCTLGGAWSGVPPSCKYVNCGT--PTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNG 564
S+ CT G WS P+C+ +C + G VL G+ F C+ + L G
Sbjct: 336 ASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGR-VLFPVNLQLGAKVDFVCDEGFQLKG 394
Query: 565 AEELVC---NRDGKWSYDIPSCELTSCPEPEV-PSGGY----MEAFDY--YVHSTINFHC 614
+ C + W+ +P CE CP P V P+G + +E F + V+ T + H
Sbjct: 395 SSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHP 454
Query: 615 EAGHK--LIGEPNLVCQQD----GEWSGDSPTCEYIDCGKLPT-LPYGTMELLNGTTH-- 665
+ G LIGE + C D G WS +P C + + P + ++ +
Sbjct: 455 DRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFP 514
Query: 666 LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRS 725
+G+ ++Y C Y P TC + WS C+ C P D
Sbjct: 515 IGTSLKYECRPEY-YGRPFSITCLDNLVWSSPKDVCKRKSCKTP------------PDPV 561
Query: 726 HGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTCQY 782
+G + T D+ ++G+ + Y C G+++IG S + C +G WS P CQ
Sbjct: 562 NGMVHVIT----DI----QVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQR 613
Query: 783 VDCGNPGRIENGKVTLPSNATF-YGATAFYQCDEN------WELEGVIRRMCQEN----G 831
+ CG P I NG + F YG+ Y+C+ +EL G C N G
Sbjct: 614 IPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVG 673
Query: 832 TWSLEPPIC-KEITCPDPSAQIKAGSGLLVVT--STLSIGGEAHYQCERGYNLKGHQTRT 888
WS P C C P+ + +G+LV S S+ ++C+ G+ +KG +
Sbjct: 674 IWSGPAPQCIXPNKCTPPNVE----NGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVK 729
Query: 889 CISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLF-GSSVEYYCLSQYQRVGPFLR 947
C + +W +P C + C+ P ++ + + + G V Y C Y G
Sbjct: 730 CQALNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASM 788
Query: 948 KCLDDGRWSGEEPSCEL 964
+C G WS P+CE+
Sbjct: 789 RCTPQGDWSPAAPTCEV 805
Score = 196 bits (477), Expect = 5e-49
Identities = 181/674 (26%), Positives = 262/674 (38%), Gaps = 82/674 (12%)
Query: 353 CGSPDKLLNTTILGNDYDV---GSRIVYKC---PE---GHMLLGDKSRHCKKD----GFW 399
C SP + N G +V G + Y C P+ L+G+ + C D G W
Sbjct: 1321 CPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVW 1380
Query: 400 SGAPPSCKYV-NCGGLTPIEDGDVALIDNRTTH--GARALYSCRENFTLVGNP-ERTCGD 455
S P C + +C + N + G Y CR + G P TC D
Sbjct: 1381 SSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEY--YGRPFSITCLD 1438
Query: 456 EGIWDGEAPRCLFDWCPDPPAVSNASV-TVNGHKAGSLASYTCENGHILSGSTSVTCTLG 514
+W C C PP N V + GS +Y+C GH L G +S C L
Sbjct: 1439 NLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIXVGSRINYSCTTGHRLIGHSSAECILS 1498
Query: 515 GA---WSGVPPSCKYVNCGTP-TIHKGSFVLINGTTT-YGSIAQFTCEPD------YWLN 563
G WS PP C+ + CG P TI G F+ N YGS+ + C + L
Sbjct: 1499 GNTAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELV 1558
Query: 564 GAEELVC--NRD--GKWSYDIPSCELTS-CPEPEVPSGGYMEAFD--YYVHSTINFHCEA 616
G + C N D G WS P C + + C P V +G + + ++ + F C+
Sbjct: 1559 GEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQP 1618
Query: 617 GHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHL-GSVIQYSCT 675
G + G + CQ +W + P+C + C P + +G + G + YSC
Sbjct: 1619 GFVMKGPRRVKCQALNKWEPELPSCSRV-CQPPPEILHGEHTPSHQDNFSPGQEVFYSCE 1677
Query: 676 TNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSD 735
Y L G CT + WS +PRC C D + HG L +
Sbjct: 1678 PGYDLRGAASLHCTPQGDWSPEAPRCAVKSCDDFL-----------GQLPHGRVLFPLN- 1725
Query: 736 NRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTCQYVDCGNPGRIE 792
++GA V + C++G+++ G S+S C G W+ + P C+++ C NP I
Sbjct: 1726 -------LQLGAKVSFVCDEGFRLKGSSVSHCVLVGMRSLWNNSVPVCEHIFCPNPPAIL 1778
Query: 793 NGKVT-LPSNATFYGATAFYQCDEN------WELEGVIRRMCQE----NGTWSLEPPICK 841
NG+ T PS YG Y CD + + L G C NG WS P C+
Sbjct: 1779 NGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTSDPHGNGVWSSPAPRCE 1838
Query: 842 EIT----CPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNG 897
C P A + + +G +Y+C GY K +C+ W+
Sbjct: 1839 LSVRAGHCKTPEQFPFASPTIPINDFEFPVGTSLNYECRPGYFGKMFSI-SCLENLVWSS 1897
Query: 898 TVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGR--- 954
C C P NG + I N T FGS+V Y C ++ +G CL G
Sbjct: 1898 VEDNCRRKSCGPPPEPFNGMVHI-NTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVT 1956
Query: 955 WSGEEPSCELATNE 968
W + P CE+ + E
Sbjct: 1957 WDKKAPICEIISCE 1970
Score = 188 bits (459), Expect = 7e-47
Identities = 174/666 (26%), Positives = 262/666 (39%), Gaps = 79/666 (11%)
Query: 353 CGSPDKLLNTTILGNDYDV---GSRIVYKC---PE---GHMLLGDKSRHCKKD----GFW 399
C SP + N G +V G + Y C P+ L+G+ + C D G W
Sbjct: 421 CPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVW 480
Query: 400 SGAPPSCKYV-NCGGLTPIEDGDVALIDNRTTH--GARALYSCRENFTLVGNP-ERTCGD 455
S P C + +C + N + G Y CR + G P TC D
Sbjct: 481 SSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEY--YGRPFSITCLD 538
Query: 456 EGIWDGEAPRCLFDWCPDPPAVSNASV-TVNGHKAGSLASYTCENGHILSGSTSVTCTLG 514
+W C C PP N V + + GS +Y+C GH L G +S C L
Sbjct: 539 NLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILS 598
Query: 515 GA---WSGVPPSCKYVNCGTP-TIHKGSFVLINGTTT-YGSIAQFTCEPD------YWLN 563
G WS PP C+ + CG P TI G F+ N YGS+ + C P + L
Sbjct: 599 GNAAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELV 658
Query: 564 GAEELVC--NRD--GKWSYDIPSCELTS-CPEPEVPSGGYMEAFD--YYVHSTINFHCEA 616
G + C N D G WS P C + C P V +G + + ++ + F C+
Sbjct: 659 GEPSIYCTSNDDQVGIWSGPAPQCIXPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQP 718
Query: 617 GHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHL-GSVIQYSCT 675
G + G + CQ +W + P+C + C P + + + G + YSC
Sbjct: 719 GFVMKGPRRVKCQALNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCE 777
Query: 676 TNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSD 735
Y L G CT + WS ++P CE C D + +G L +
Sbjct: 778 PGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDFM-----------GQLLNGRVLFPVN- 825
Query: 736 NRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTCQYVDCGNPGRIE 792
++GA V + C++G+++ G S S C G W+ + P C+ + C +P I
Sbjct: 826 -------LQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIP 878
Query: 793 NGKVT-LPSNATFYGATAFYQCD------ENWELEGVIRRMC----QENGTWSLEPPICK 841
NG+ T P +G T Y CD +++L G C Q NG WS P C
Sbjct: 879 NGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCG 938
Query: 842 EI-TCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVP 900
+ C P + A S IG Y+C Y + TC+ W+
Sbjct: 939 ILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGRPFSI-TCLDNLVWSSPKD 997
Query: 901 VCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDG---RWSG 957
VC C++P + NG + + + GS + Y C + ++ +G +C+ G WS
Sbjct: 998 VCKRKSCKTPPDPVNGMVHVITDIQV-GSRINYSCTTGHRLIGHSSAECILSGNAAHWST 1056
Query: 958 EEPSCE 963
+ P C+
Sbjct: 1057 KPPICQ 1062
Score = 187 bits (456), Expect = 2e-46
Identities = 169/660 (25%), Positives = 261/660 (39%), Gaps = 77/660 (11%)
Query: 358 KLLNTTILGN-DYDVGSRIVYKCPEGHMLLGDKSRHCKKDGF---WSGAPPSCKYVNCGG 413
+LLN +L + +G+++ + C EG L G + +C G W+ + P C+ + C
Sbjct: 364 QLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPS 423
Query: 414 LTPIEDGDVALIDNRTTHGARAL-YSCREN------FTLVGNPERTCGDE----GIWDGE 462
I +G +A+ Y+C + F L+G C + G+W
Sbjct: 424 PPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSP 483
Query: 463 APRC-LFDWCPDPP----AVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAW 517
APRC + C P A + G+ Y C + S+TC W
Sbjct: 484 APRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYY-GRPFSITCLDNLVW 542
Query: 518 SGVPPSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGK-- 575
S CK +C TP V + GS ++C + L G C G
Sbjct: 543 SSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAA 602
Query: 576 -WSYDIPSCELTSCP-EPEVPSGGYMEAF--DYYVHSTINFHCEAGH------KLIGEPN 625
WS P C+ C P + +G ++ +++ S + + C G +L+GEP+
Sbjct: 603 HWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPS 662
Query: 626 LVC----QQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTH-LGSVIQYSCTTNYRL 680
+ C Q G WSG +P C + P + G + N + L V+++ C + +
Sbjct: 663 IYCTSNDDQVGIWSGPAPQCIXPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVM 722
Query: 681 VGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVG 740
GP R C +W P C + C P D H R DN
Sbjct: 723 KGPRRVKCQALNKWEPELPSCSRV-CQPP------------PDVLHAERTQRDKDN---- 765
Query: 741 NTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGN-PGRIENGKVTLP 799
+ G V Y CE GY + G + C G WS PTC+ C + G++ NG+V P
Sbjct: 766 --FSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFP 823
Query: 800 SNATFYGATAFYQCDENWELEGVIRRMCQENGT---WSLEPPICKEITCPDPSAQIKAGS 856
N GA + CDE ++L+G C G W+ P+C++I CP P I G
Sbjct: 824 VNLQL-GAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPV-IPNGR 881
Query: 857 GLLVVTSTLSIGGEAHYQCE----RG--YNLKGHQTRTCIS----KGQWNGTVPVC-IPI 905
G +Y C+ RG ++L G T C S G W+ P C I
Sbjct: 882 HTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILG 941
Query: 906 DCRSPGNIENGKIVISNGSTLF--GSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
C++P + K+ ++ F G+S++Y C +Y PF CLD+ WS + C+
Sbjct: 942 HCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYG-RPFSITCLDNLVWSSPKDVCK 1000
Score = 187 bits (455), Expect = 2e-46
Identities = 173/666 (25%), Positives = 261/666 (39%), Gaps = 79/666 (11%)
Query: 353 CGSPDKLLNTTILGNDYDV---GSRIVYKC---PE---GHMLLGDKSRHCKKD----GFW 399
C SP + N G +V G + Y C P+ L+G+ + C D G W
Sbjct: 871 CPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVW 930
Query: 400 SGAPPSCKYV-NCGGLTPIEDGDVALIDNRTTH--GARALYSCRENFTLVGNP-ERTCGD 455
S P C + +C + N + G Y CR + G P TC D
Sbjct: 931 SSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEY--YGRPFSITCLD 988
Query: 456 EGIWDGEAPRCLFDWCPDPPAVSNASV-TVNGHKAGSLASYTCENGHILSGSTSVTCTLG 514
+W C C PP N V + + GS +Y+C GH L G +S C L
Sbjct: 989 NLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILS 1048
Query: 515 GA---WSGVPPSCKYVNCGTP-TIHKGSFVLINGTTT-YGSIAQFTCEPD------YWLN 563
G WS PP C+ + CG P TI G F+ N YGS+ + C P + L
Sbjct: 1049 GNAAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELV 1108
Query: 564 GAEELVC--NRD--GKWSYDIPSCELTS-CPEPEVPSGGYMEAFD--YYVHSTINFHCEA 616
G + C N D G WS P C + C P V +G + + ++ + F C+
Sbjct: 1109 GEPSIYCTSNDDQVGIWSGPAPQCIXPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQP 1168
Query: 617 GHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHL-GSVIQYSCT 675
G + G + CQ +W + P+C + C P + + + G + YSC
Sbjct: 1169 GFVMKGPRRVKCQALNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCE 1227
Query: 676 TNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSD 735
Y L G CT + WS ++P CE C D + +G L +
Sbjct: 1228 PGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDFM-----------GQLLNGRVLFPVN- 1275
Query: 736 NRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTCQYVDCGNPGRIE 792
++GA V + C++G+++ G S S C G W+ + P C+ + C +P I
Sbjct: 1276 -------LQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIP 1328
Query: 793 NGKVT-LPSNATFYGATAFYQCD------ENWELEGVIRRMC----QENGTWSLEPPICK 841
NG+ T P +G Y CD +++L G C Q NG WS P C
Sbjct: 1329 NGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCG 1388
Query: 842 EI-TCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVP 900
+ C P + A S IG Y+C Y + TC+ W+
Sbjct: 1389 ILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGRPFSI-TCLDNLVWSSPKD 1447
Query: 901 VCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDG---RWSG 957
VC C++P + NG + + + GS + Y C + ++ +G +C+ G WS
Sbjct: 1448 VCKRKSCKTPPDPVNGMVHVITDIXV-GSRINYSCTTGHRLIGHSSAECILSGNTAHWST 1506
Query: 958 EEPSCE 963
+ P C+
Sbjct: 1507 KPPICQ 1512
Score = 169 bits (411), Expect = 5e-41
Identities = 135/509 (26%), Positives = 209/509 (41%), Gaps = 59/509 (11%)
Query: 490 GSLASYTCENGHILSGST-SVTCTLGGAWSGVPPSCKYVNCGTPTIHKGSFVLINGTTTY 548
G+ +Y C G+ SG S+ C W+G C+ +C P V + +
Sbjct: 66 GTYLNYECRPGY--SGRPFSIICLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKGIQF 123
Query: 549 GSIAQFTCEPDYWLNGAEELVCNRDGK---WSYDIPSCELTSCP-EPEVPSGGYMEAF-- 602
GS +++C Y L G+ C G W + P C+ C P + +G ++
Sbjct: 124 GSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTITNGDFISTNRE 183
Query: 603 DYYVHSTINFHCEAGH------KLIGEPNLVC----QQDGEWSGDSPTCEYIDCGKLPTL 652
+++ S + + C G +L+GEP++ C Q G WSG +P C + P +
Sbjct: 184 NFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNV 243
Query: 653 PYGTMELLNGTTH-LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIV 711
G + N + L V+++ C + + GP R C +W P C + C P
Sbjct: 244 ENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRV-CQPP-- 300
Query: 712 AEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNG 771
D H R DN + G V Y CE GY + G + C G
Sbjct: 301 ----------PDVLHAERTQRDKDN------FSPGQEVFYSCEPGYDLRGAASMRCTPQG 344
Query: 772 QWSGTTPTCQYVDCGN-PGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQEN 830
WS PTC+ C + G++ NG+V P N GA + CDE ++L+G C
Sbjct: 345 DWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQL-GAKVDFVCDEGFQLKGSSASYCVLA 403
Query: 831 GT---WSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCE----RG--YNL 881
G W+ P+C++I CP P I G G +Y C+ RG ++L
Sbjct: 404 GMESLWNSSVPVCEQIFCPSPPV-IPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDL 462
Query: 882 KGHQTRTCIS----KGQWNGTVPVC-IPIDCRSPGNIENGKIVISNGSTLF--GSSVEYY 934
G T C S G W+ P C I C++P + K+ ++ F G+S++Y
Sbjct: 463 IGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYE 522
Query: 935 CLSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
C +Y PF CLD+ WS + C+
Sbjct: 523 CRPEYYG-RPFSITCLDNLVWSSPKDVCK 550
Score = 101 bits (243), Expect = 1e-20
Identities = 80/316 (25%), Positives = 124/316 (39%), Gaps = 42/316 (13%)
Query: 666 LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRS 725
+G+ + Y C Y P C + W+ + RC C +P +V V
Sbjct: 65 IGTYLNYECRPGYS-GRPFSIICLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKG--- 120
Query: 726 HGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTCQY 782
+ G+ +KY C KGY++IG S +TC +G W TP C
Sbjct: 121 -----------------IQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDR 163
Query: 783 VDCGNPGRIENGKVTLPSNATF-YGATAFYQCDEN------WELEGVIRRMCQEN----G 831
+ CG P I NG + F YG+ Y+C+ +EL G C N G
Sbjct: 164 IPCGLPPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVG 223
Query: 832 TWSLEPPICKEITCPDPSAQIKAGSGLLVV--TSTLSIGGEAHYQCERGYNLKGHQTRTC 889
WS P C P+ +G+LV S S+ ++C+ G+ +KG + C
Sbjct: 224 IWSGPAPQC---IIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKC 280
Query: 890 ISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLF-GSSVEYYCLSQYQRVGPFLRK 948
+ +W +P C + C+ P ++ + + + G V Y C Y G +
Sbjct: 281 QALNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMR 339
Query: 949 CLDDGRWSGEEPSCEL 964
C G WS P+CE+
Sbjct: 340 CTPQGDWSPAAPTCEV 355
Score = 44.0 bits (99), Expect = 0.003
Identities = 17/42 (40%), Positives = 24/42 (57%)
Query: 17 NEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
+++N G Y C+ GY+L GA CT +GDW+ E P C
Sbjct: 1662 HQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGDWSPEAPRC 1703
Score = 42.7 bits (96), Expect = 0.007
Identities = 18/57 (31%), Positives = 28/57 (49%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C P + ++ +++N G Y C+ Y+L GA CT +GDW+ E P C
Sbjct: 2100 CQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCTPQGDWSPEAPRC 2156
Score = 42.3 bits (95), Expect = 0.009
Identities = 19/57 (33%), Positives = 28/57 (49%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C P +A + +++N G Y C+ GY+L GA CT +GDW+ P C
Sbjct: 297 CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTC 353
Score = 42.3 bits (95), Expect = 0.009
Identities = 19/57 (33%), Positives = 28/57 (49%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C P +A + +++N G Y C+ GY+L GA CT +GDW+ P C
Sbjct: 747 CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTC 803
Score = 42.3 bits (95), Expect = 0.009
Identities = 19/57 (33%), Positives = 28/57 (49%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C P +A + +++N G Y C+ GY+L GA CT +GDW+ P C
Sbjct: 1197 CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTC 1253
Score = 37.9 bits (84), Expect = 0.20
Identities = 20/60 (33%), Positives = 27/60 (45%), Gaps = 5/60 (8%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGD---WTLEPPFC 58
C P P N V + + I G+ Y C G+ L G EC L G+ W+ +PP C
Sbjct: 1454 CKTPPDPVNGMVHVITD--IXVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPIC 1511
Score = 37.5 bits (83), Expect = 0.26
Identities = 20/60 (33%), Positives = 27/60 (45%), Gaps = 5/60 (8%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGD---WTLEPPFC 58
C +P P N V + + I G+ Y C +GY L G+ C + GD W E P C
Sbjct: 104 CRNPPDPVNGMVHVI--KGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPIC 161
Score = 37.5 bits (83), Expect = 0.26
Identities = 20/60 (33%), Positives = 27/60 (45%), Gaps = 5/60 (8%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGD---WTLEPPFC 58
C P P N V + + I G+ Y C G+ L G EC L G+ W+ +PP C
Sbjct: 554 CKTPPDPVNGMVHVITD--IQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPIC 611
Score = 37.5 bits (83), Expect = 0.26
Identities = 20/60 (33%), Positives = 27/60 (45%), Gaps = 5/60 (8%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGD---WTLEPPFC 58
C P P N V + + I G+ Y C G+ L G EC L G+ W+ +PP C
Sbjct: 1004 CKTPPDPVNGMVHVITD--IQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPIC 1061
Score = 37.5 bits (83), Expect = 0.26
Identities = 19/60 (31%), Positives = 27/60 (45%), Gaps = 5/60 (8%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGD---WTLEPPFC 58
CG P P N V I + G+ Y C+EG+ L G+ C + G+ W + P C
Sbjct: 1907 CGPPPEPFNGMVHINTDTQF--GSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPIC 1964
>AL691452-3|CAI16723.1| 2039|Homo sapiens complement component (3b/4b)
receptor 1 (Knops blood group) protein.
Length = 2039
Score = 234 bits (573), Expect = 1e-60
Identities = 194/665 (29%), Positives = 275/665 (41%), Gaps = 78/665 (11%)
Query: 352 TCGSPDKLLNTTI-LGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDG---FWSGAPPSCK 407
+C +P +N + + D VGSRI Y C GH L+G S C G WS PP C+
Sbjct: 553 SCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQ 612
Query: 408 YVNCGGLTPIEDGDVALIDNRTTH-GARALYSC------RENFTLVGNPERTC--GDE-- 456
+ CG I +GD + H G+ Y C R+ F LVG P C D+
Sbjct: 613 RIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQV 672
Query: 457 GIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGSL---ASYTCENGHILSGSTSVTCTL 513
GIW G AP+C+ PP V N + + SL + C+ G ++ G V C
Sbjct: 673 GIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQA 732
Query: 514 GGAWSGVPPSCKYVNCGTP--TIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCN 571
W PSC V C P +H + G ++CEP Y L GA + C
Sbjct: 733 LNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCT 791
Query: 572 RDGKWSYDIPSCELTSCPE--PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQ 629
G WS P+CE+ SC + ++ +G + + + + ++F C+ G +L G C
Sbjct: 792 PQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCV 851
Query: 630 QDGE---WSGDSPTCEYIDCGKLPTLPYG--TMELLNGTTHLGSVIQYSCT------TNY 678
G W+ P CE I C P +P G T + L G + Y+C T++
Sbjct: 852 LAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLE-VFPFGKAVNYTCDPHPDRGTSF 910
Query: 679 RLVGPVRRTCTEEFQ----WSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTS 734
L+G CT + Q WS +PRC + G+ ++ H L
Sbjct: 911 DLIGESTIRCTSDPQGNGVWSSPAPRC----------------GILGHCQAPDHFLFAKL 954
Query: 735 DNRDVGNTYRIGALVKYRCEKGYKVIGESLS-TCEDNGQWSGTTPTCQYVDCGNPGRIEN 793
+ + + IG +KY C Y G S TC DN WS C+ C P N
Sbjct: 955 KTQTNASDFPIGTSLKYECRPEY--YGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVN 1012
Query: 794 GKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGT---WSLEPPICKEITCPDPSA 850
G V + ++ G+ Y C L G C +G WS +PPIC+ I C P
Sbjct: 1013 GMVHVITDIQV-GSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPCGLPPT 1071
Query: 851 QIKAGSGLLVVTSTLSIGGEAHYQCERG------YNLKGHQTRTCISK----GQWNGTVP 900
I G + G Y+C G + L G + C S G W+G P
Sbjct: 1072 -IANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAP 1130
Query: 901 VC-IPIDCRSPGNIENGKIVISNGSTLFGSS--VEYYCLSQYQRVGPFLRKCLDDGRWSG 957
C IP C +P N+ENG I++S+ +LF + VE+ C + GP KC +W
Sbjct: 1131 QCIIPNKC-TPPNVENG-ILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEP 1188
Query: 958 EEPSC 962
E PSC
Sbjct: 1189 ELPSC 1193
Score = 227 bits (555), Expect = 2e-58
Identities = 187/662 (28%), Positives = 274/662 (41%), Gaps = 69/662 (10%)
Query: 352 TCGSPDKLLNTTI-LGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDG---FWSGAPPSCK 407
+C +P +N + + D VGSRI Y C GH L+G S C G WS PP C+
Sbjct: 1003 SCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQ 1062
Query: 408 YVNCGGLTPIEDGDVALIDNRTTH-GARALYSC------RENFTLVGNPERTC--GDE-- 456
+ CG I +GD + H G+ Y C R+ F LVG P C D+
Sbjct: 1063 RIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQV 1122
Query: 457 GIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGSL---ASYTCENGHILSGSTSVTCTL 513
GIW G AP+C+ PP V N + + SL + C+ G ++ G V C
Sbjct: 1123 GIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQA 1182
Query: 514 GGAWSGVPPSCKYVNCGTPTIHKGSFVLINGTT-TYGSIAQFTCEPDYWLNGAEELVCNR 572
W PSC V P I G + + G ++CEP Y L GA L C
Sbjct: 1183 LNKWEPELPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTP 1242
Query: 573 DGKWSYDIPSCELTSCPE--PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQ 630
G WS + P C + SC + ++P G + + + + ++F C+ G +L G C
Sbjct: 1243 QGDWSPEAPRCAVKSCDDFLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCVL 1302
Query: 631 DGE---WSGDSPTCEYIDCGKLPTLPYGT-MELLNGTTHLGSVIQYSCTTN------YRL 680
G W+ P CE+I C P + G +G G I Y+C + + L
Sbjct: 1303 VGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNL 1362
Query: 681 VGPVRRTCTEEFQ----WSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDN 736
+G CT + WS +PRCE ++ ++ T I +D
Sbjct: 1363 IGESTIRCTSDPHGNGVWSSPAPRCE--------LSVRAGHCKTPEQFPFASPTIPINDF 1414
Query: 737 RDVGNTYRIGALVKYRCEKGYKVIGESLS-TCEDNGQWSGTTPTCQYVDCGNPGRIENGK 795
+ +G + Y C GY G+ S +C +N WS C+ CG P NG
Sbjct: 1415 E-----FPVGTSLNYECRPGY--FGKMFSISCLENLVWSSVEDNCRRKSCGPPPEPFNGM 1467
Query: 796 VTLPSNATFYGATAFYQCDENWELEGVIRRMCQENG---TWSLEPPICKEITCPDPSAQI 852
V + ++ T +G+T Y C+E + L G C +G TW + PIC+ I+C +P I
Sbjct: 1468 VHINTD-TQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISC-EPPPTI 1525
Query: 853 KAGSGLLVVTSTLSIGGEAHYQCERG------YNLKGHQTRTCISK----GQWNGTVPVC 902
G ++ G YQC G + L G ++ C SK G W+ P C
Sbjct: 1526 SNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRC 1585
Query: 903 IPID-CRSPGNIENGKIVISNGSTL-FGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEP 960
I + C +P +EN V N S + + C + VG +C +GRW + P
Sbjct: 1586 ISTNKCTAP-EVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLP 1644
Query: 961 SC 962
C
Sbjct: 1645 HC 1646
Score = 224 bits (547), Expect = 2e-57
Identities = 175/645 (27%), Positives = 261/645 (40%), Gaps = 74/645 (11%)
Query: 368 DYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDN 427
++ +G+ + Y+C G+ S C K+ W+GA C+ +C +G V +I
Sbjct: 62 EFPIGTYLNYECRPGYSGR-PFSIICLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKG 120
Query: 428 RTTHGARALYSCRENFTLVGNPERTC---GDEGIWDGEAPRCLFDWCPDPPAVSNA---S 481
G++ YSC + + L+G+ TC GD IWD E P C C PP ++N S
Sbjct: 121 -IQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTIANGDFIS 179
Query: 482 VTVNGHKAGSLASYTCENG------HILSGSTSVTCTLG----GAWSGVPPSCKYVN-CG 530
GS+ +Y C G L G S+ CT G WSG P C N C
Sbjct: 180 TNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCT 239
Query: 531 TPTIHKGSFVLINGTT-TYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCP 589
P + G V N + + + +F C+P + + G + C KW ++PSC P
Sbjct: 240 PPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQP 299
Query: 590 EPEV--PSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCG 647
P+V + ++ + + CE G+ L G ++ C G+WS +PTCE C
Sbjct: 300 PPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCD 359
Query: 648 KLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCT---EEFQWSDSSPRCEEI 704
L LG+ + + C ++L G C E W+ S P CE+I
Sbjct: 360 DFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQI 419
Query: 705 RCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCE------KGYK 758
C P V N R G L + G V Y C+ +
Sbjct: 420 FCPSP--------PVIPNGRHTGKPL----------EVFPFGKTVNYTCDPHPDRGTSFD 461
Query: 759 VIGESLSTC----EDNGQWSGTTPTCQYV-DCGNPGRIENGKVTLPSNATFY--GATAFY 811
+IGES C + NG WS P C + C P K+ +NA+ + G + Y
Sbjct: 462 LIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKY 521
Query: 812 QCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEA 871
+C + C +N WS +CK +C P + +G++ V + + +G
Sbjct: 522 ECRPEY-YGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPV---NGMVHVITDIQVGSRI 577
Query: 872 HYQCERGYNLKGHQTRTCISKG---QWNGTVPVCIPIDCRSPGNIENGKIVISNGSTL-F 927
+Y C G+ L GH + CI G W+ P+C I C P I NG + +N +
Sbjct: 578 NYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHY 637
Query: 928 GSSVEYYC------LSQYQRVGPFLRKCL--DD--GRWSGEEPSC 962
GS V Y C ++ VG C DD G WSG P C
Sbjct: 638 GSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQC 682
Score = 221 bits (541), Expect = 8e-57
Identities = 188/665 (28%), Positives = 271/665 (40%), Gaps = 78/665 (11%)
Query: 352 TCGSPDKLLNTTI-LGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDG---FWSGAPPSCK 407
+C +P +N + + GS+I Y C +G+ L+G S C G W P C
Sbjct: 103 SCRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICD 162
Query: 408 YVNCGGLTPIEDGDVALIDNRTTH-GARALYSC------RENFTLVGNPERTC--GDE-- 456
+ CG I +GD + H G+ Y C R+ F LVG P C D+
Sbjct: 163 RIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQV 222
Query: 457 GIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGSL---ASYTCENGHILSGSTSVTCTL 513
GIW G AP+C+ PP V N + + SL + C+ G ++ G V C
Sbjct: 223 GIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQA 282
Query: 514 GGAWSGVPPSCKYVNCGTP--TIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCN 571
W PSC V C P +H + G ++CEP Y L GA + C
Sbjct: 283 LNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCT 341
Query: 572 RDGKWSYDIPSCELTSCPE--PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQ 629
G WS P+CE+ SC + ++ +G + + + + ++F C+ G +L G C
Sbjct: 342 PQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCV 401
Query: 630 QDGE---WSGDSPTCEYIDCGKLPTLPYG--TMELLNGTTHLGSVIQYSCT------TNY 678
G W+ P CE I C P +P G T + L G + Y+C T++
Sbjct: 402 LAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLE-VFPFGKTVNYTCDPHPDRGTSF 460
Query: 679 RLVGPVRRTCTEEFQ----WSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTS 734
L+G CT + Q WS +PRC + G+ ++ H L
Sbjct: 461 DLIGESTIRCTSDPQGNGVWSSPAPRC----------------GILGHCQAPDHFLFAKL 504
Query: 735 DNRDVGNTYRIGALVKYRCEKGYKVIGESLS-TCEDNGQWSGTTPTCQYVDCGNPGRIEN 793
+ + + IG +KY C Y G S TC DN WS C+ C P N
Sbjct: 505 KTQTNASDFPIGTSLKYECRPEY--YGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVN 562
Query: 794 GKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGT---WSLEPPICKEITCPDPSA 850
G V + ++ G+ Y C L G C +G WS +PPIC+ I C P
Sbjct: 563 GMVHVITDIQV-GSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPT 621
Query: 851 QIKAGSGLLVVTSTLSIGGEAHYQCERG------YNLKGHQTRTCISK----GQWNGTVP 900
I G + G Y+C G + L G + C S G W+G P
Sbjct: 622 -IANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAP 680
Query: 901 VC-IPIDCRSPGNIENGKIVISNGSTLFGSS--VEYYCLSQYQRVGPFLRKCLDDGRWSG 957
C IP C +P N+ENG I++S+ +LF + VE+ C + GP KC +W
Sbjct: 681 QCIIPNKC-TPPNVENG-ILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEP 738
Query: 958 EEPSC 962
E PSC
Sbjct: 739 ELPSC 743
Score = 205 bits (501), Expect = 6e-52
Identities = 178/668 (26%), Positives = 269/668 (40%), Gaps = 72/668 (10%)
Query: 353 CGSPDKLL----NTTILGNDYDVGSRIVYKC-PEGHMLLGDKSRHCKKDGFWSGAPPSCK 407
C +PD L T +D+ +G+ + Y+C PE + S C + WS CK
Sbjct: 943 CQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGR--PFSITCLDNLVWSSPKDVCK 1000
Query: 408 YVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTC---GDEGIWDGEAP 464
+C +G V +I + G+R YSC L+G+ C G+ W + P
Sbjct: 1001 RKSCKTPPDPVNGMVHVITDIQV-GSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPP 1059
Query: 465 RCLFDWCPDPPAVSNAS-VTVNGHKA--GSLASYTCENGHI------LSGSTSVTCTLG- 514
C C PP ++N ++ N GS+ +Y C G L G S+ CT
Sbjct: 1060 ICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSND 1119
Query: 515 ---GAWSGVPPSCKYVN-CGTPTIHKGSFVLINGTT-TYGSIAQFTCEPDYWLNGAEELV 569
G WSG P C N C P + G V N + + + +F C+P + + G +
Sbjct: 1120 DQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVK 1179
Query: 570 CNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAF--DYYVHSTINFHCEAGHKLIGEPNLV 627
C KW ++PSC P PE+ G + + ++ + + CE G+ L G +L
Sbjct: 1180 CQALNKWEPELPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLH 1239
Query: 628 CQQDGEWSGDSPTCEYIDCGK-LPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRR 686
C G+WS ++P C C L LP+G + L LG+ + + C +RL G
Sbjct: 1240 CTPQGDWSPEAPRCAVKSCDDFLGQLPHGRV-LFPLNLQLGAKVSFVCDEGFRLKGSSVS 1298
Query: 687 TCT---EEFQWSDSSPRCEEIRCSDP-IVAEKSIVSVTGNDRSHGHTLIRTSD-NRDVGN 741
C W++S P CE I C +P + D +G + T D + D G
Sbjct: 1299 HCVLVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGM 1358
Query: 742 TYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYV----DCGNPGRIENGKVT 797
T+ + RC S NG WS P C+ C P + T
Sbjct: 1359 TFNLIGESTIRCT----------SDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPT 1408
Query: 798 LPSNATFY--GATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAG 855
+P N + G + Y+C + + C EN WS C+ +C P
Sbjct: 1409 IPINDFEFPVGTSLNYECRPGY-FGKMFSISCLENLVWSSVEDNCRRKSCGPPPEPF--- 1464
Query: 856 SGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQ---WNGTVPVCIPIDCRSPGN 912
+G++ + + G +Y C G+ L G + TC+ G W+ P+C I C P
Sbjct: 1465 NGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPT 1524
Query: 913 IENGKIVISNGSTLF--GSSVEYYCLS------QYQRVGPFLRKCL--DD--GRWSGEEP 960
I NG SN T F G+ V Y C + ++ VG C DD G WS P
Sbjct: 1525 ISNGDF-YSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPP 1583
Query: 961 SCELATNE 968
C ++TN+
Sbjct: 1584 RC-ISTNK 1590
Score = 200 bits (488), Expect = 2e-50
Identities = 170/650 (26%), Positives = 256/650 (39%), Gaps = 79/650 (12%)
Query: 371 VGSRIVYKCPEGHMLLGDKSRHCKKDGF---WSGAPPSCKYVNCGGLTPIEDG-DVALID 426
+G+++ + C EG L G HC G W+ + P C+++ C I +G
Sbjct: 1278 LGAKVSFVCDEGFRLKGSSVSHCVLVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPS 1337
Query: 427 NRTTHGARALYSCREN------FTLVGNPERTCGDE----GIWDGEAPRCLFD----WCP 472
+G Y+C + F L+G C + G+W APRC C
Sbjct: 1338 GDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTSDPHGNGVWSSPAPRCELSVRAGHCK 1397
Query: 473 DPPAVSNASVTV--NGHK--AGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVN 528
P AS T+ N + G+ +Y C G+ S++C WS V +C+ +
Sbjct: 1398 TPEQFPFASPTIPINDFEFPVGTSLNYECRPGYF-GKMFSISCLENLVWSSVEDNCRRKS 1456
Query: 529 CGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGK---WSYDIPSCEL 585
CG P V IN T +GS ++C + L G+ C G W P CE+
Sbjct: 1457 CGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEI 1516
Query: 586 TSC-PEPEVPSGGYM--EAFDYYVHSTINFHCEAG------HKLIGEPNLVC----QQDG 632
SC P P + +G + ++ + + + C G +L+GE ++ C Q G
Sbjct: 1517 ISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVG 1576
Query: 633 EWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTH-LGSVIQYSCTTNYRLVGPVRRTCTEE 691
WS P C + P + N + L +I++ C + +VG C
Sbjct: 1577 VWSSPPPRCISTNKCTAPEVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTN 1636
Query: 692 FQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKY 751
+W P C + C P + HG + DN + G V Y
Sbjct: 1637 GRWGPKLPHCSRV-CQPP------------PEILHGEHTLSHQDN------FSPGQEVFY 1677
Query: 752 RCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGN-PGRIENGKVTLPSNATFYGATAF 810
CE Y + G + C G WS P C C + G++ +G+V LP N GA
Sbjct: 1678 SCEPSYDLRGAASLHCTPQGDWSPEAPRCTVKSCDDFLGQLPHGRVLLPLNLQL-GAKVS 1736
Query: 811 YQCDENWELEGVIRRMCQENG---TWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSI 867
+ CDE + L+G C G W+ P+C++I CP+P A I G +
Sbjct: 1737 FVCDEGFRLKGRSASHCVLAGMKALWNSSVPVCEQIFCPNPPA-ILNGRHTGTPFGDIPY 1795
Query: 868 GGEAHYQC----ERG--YNLKGHQTRTCIS----KGQWNGTVPVC---IPIDCRSPGNIE 914
G E Y C +RG +NL G + C S G W+ P C +P C P I+
Sbjct: 1796 GKEISYACDTHPDRGMTFNLIGESSIRCTSDPQGNGVWSSPAPRCELSVPAACPHPPKIQ 1855
Query: 915 NGKIVISNGST-LFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
NG + + S L G ++ Y C Y VG C D G WS + C+
Sbjct: 1856 NGHYIGGHVSLYLPGMTISYICDPGYLLVGKGFIFCTDQGIWSQLDHYCK 1905
Score = 197 bits (480), Expect = 2e-49
Identities = 174/678 (25%), Positives = 274/678 (40%), Gaps = 90/678 (13%)
Query: 345 ICQYLPPTCGSPDKLLNTTILGND---YDVGSRIVYKCPEGH------MLLGDKSRHCKK 395
IC +P CG P + N + + + GS + Y+C G L+G+ S +C
Sbjct: 160 ICDRIP--CGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTS 217
Query: 396 D----GFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRTTHGARAL--YSCRENFTLVGNP 449
+ G WSG P C N +E+G + + DNR+ + + C+ F + G
Sbjct: 218 NDDQVGIWSGPAPQCIIPNKCTPPNVENG-ILVSDNRSLFSLNEVVEFRCQPGFVMKGPR 276
Query: 450 ERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTV---NGHKAGSLASYTCENGHILSGS 506
C W+ E P C C PP V +A T + G Y+CE G+ L G+
Sbjct: 277 RVKCQALNKWEPELPSCS-RVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGA 335
Query: 507 TSVTCTLGGAWSGVPPSCKYVNCGT--PTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNG 564
S+ CT G WS P+C+ +C + G VL G+ F C+ + L G
Sbjct: 336 ASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGR-VLFPVNLQLGAKVDFVCDEGFQLKG 394
Query: 565 AEELVC---NRDGKWSYDIPSCELTSCPEPEV-PSGGY----MEAFDYYVHSTINFHCE- 615
+ C + W+ +P CE CP P V P+G + +E F + T+N+ C+
Sbjct: 395 SSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPF--GKTVNYTCDP 452
Query: 616 -----AGHKLIGEPNLVCQQD----GEWSGDSPTCEYIDCGKLPT-LPYGTMELLNGTTH 665
LIGE + C D G WS +P C + + P + ++ +
Sbjct: 453 HPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASD 512
Query: 666 --LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGND 723
+G+ ++Y C Y P TC + WS C+ C P D
Sbjct: 513 FPIGTSLKYECRPEY-YGRPFSITCLDNLVWSSPKDVCKRKSCKTP------------PD 559
Query: 724 RSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTC 780
+G + T D+ ++G+ + Y C G+++IG S + C +G WS P C
Sbjct: 560 PVNGMVHVIT----DI----QVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPIC 611
Query: 781 QYVDCGNPGRIENGKVTLPSNATF-YGATAFYQCDEN------WELEGVIRRMCQEN--- 830
Q + CG P I NG + F YG+ Y+C+ +EL G C N
Sbjct: 612 QRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQ 671
Query: 831 -GTWSLEPPICKEITCPDPSAQIKAGSGLLVVT--STLSIGGEAHYQCERGYNLKGHQTR 887
G WS P C P+ +G+LV S S+ ++C+ G+ +KG +
Sbjct: 672 VGIWSGPAPQC---IIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRV 728
Query: 888 TCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLF-GSSVEYYCLSQYQRVGPFL 946
C + +W +P C + C+ P ++ + + + G V Y C Y G
Sbjct: 729 KCQALNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAAS 787
Query: 947 RKCLDDGRWSGEEPSCEL 964
+C G WS P+CE+
Sbjct: 788 MRCTPQGDWSPAAPTCEV 805
Score = 196 bits (479), Expect = 3e-49
Identities = 181/674 (26%), Positives = 263/674 (39%), Gaps = 82/674 (12%)
Query: 353 CGSPDKLLNTTILGNDYDV---GSRIVYKC---PE---GHMLLGDKSRHCKKD----GFW 399
C SP + N G +V G + Y C P+ L+G+ + C D G W
Sbjct: 871 CPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVW 930
Query: 400 SGAPPSCKYV-NCGGLTPIEDGDVALIDNRTTH--GARALYSCRENFTLVGNP-ERTCGD 455
S P C + +C + N + G Y CR + G P TC D
Sbjct: 931 SSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEY--YGRPFSITCLD 988
Query: 456 EGIWDGEAPRCLFDWCPDPPAVSNASV-TVNGHKAGSLASYTCENGHILSGSTSVTCTLG 514
+W C C PP N V + + GS +Y+C GH L G +S C L
Sbjct: 989 NLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILS 1048
Query: 515 GA---WSGVPPSCKYVNCGTP-TIHKGSFVLINGTTT-YGSIAQFTCEPD------YWLN 563
G WS PP C+ + CG P TI G F+ N YGS+ + C + L
Sbjct: 1049 GNTAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELV 1108
Query: 564 GAEELVC--NRD--GKWSYDIPSCELTS-CPEPEVPSGGYMEAFD--YYVHSTINFHCEA 616
G + C N D G WS P C + + C P V +G + + ++ + F C+
Sbjct: 1109 GEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQP 1168
Query: 617 GHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHL-GSVIQYSCT 675
G + G + CQ +W + P+C + C P + +G + G + YSC
Sbjct: 1169 GFVMKGPRRVKCQALNKWEPELPSCSRV-CQPPPEILHGEHTPSHQDNFSPGQEVFYSCE 1227
Query: 676 TNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSD 735
Y L G CT + WS +PRC C D + HG L +
Sbjct: 1228 PGYDLRGAASLHCTPQGDWSPEAPRCAVKSCDDFL-----------GQLPHGRVLFPLN- 1275
Query: 736 NRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTCQYVDCGNPGRIE 792
++GA V + C++G+++ G S+S C G W+ + P C+++ C NP I
Sbjct: 1276 -------LQLGAKVSFVCDEGFRLKGSSVSHCVLVGMRSLWNNSVPVCEHIFCPNPPAIL 1328
Query: 793 NGKVT-LPSNATFYGATAFYQCDEN------WELEGVIRRMCQE----NGTWSLEPPICK 841
NG+ T PS YG Y CD + + L G C NG WS P C+
Sbjct: 1329 NGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTSDPHGNGVWSSPAPRCE 1388
Query: 842 EIT----CPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNG 897
C P A + + +G +Y+C GY K +C+ W+
Sbjct: 1389 LSVRAGHCKTPEQFPFASPTIPINDFEFPVGTSLNYECRPGYFGKMFSI-SCLENLVWSS 1447
Query: 898 TVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGR--- 954
C C P NG + I N T FGS+V Y C ++ +G CL G
Sbjct: 1448 VEDNCRRKSCGPPPEPFNGMVHI-NTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVT 1506
Query: 955 WSGEEPSCELATNE 968
W + P CE+ + E
Sbjct: 1507 WDKKAPICEIISCE 1520
Score = 196 bits (477), Expect = 5e-49
Identities = 186/688 (27%), Positives = 271/688 (39%), Gaps = 83/688 (12%)
Query: 345 ICQYLPPTCGSPDKLLNTTILGN---DYDVGSRIVYKC---PEGHM---LLGDKSRHCKK 395
+C+++ C +P +LN G D G I Y C P+ M L+G+ + C
Sbjct: 1315 VCEHI--FCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTS 1372
Query: 396 D----GFWSGAPPSCKY-VNCGGLT-----PIEDGDVALIDNRTTHGARALYSCRENFTL 445
D G WS P C+ V G P + + D G Y CR +
Sbjct: 1373 DPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDFEFPVGTSLNYECRPGY-- 1430
Query: 446 VGNP-ERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGH-KAGSLASYTCENGHIL 503
G +C + +W C C PP N V +N + GS +Y+C G L
Sbjct: 1431 FGKMFSISCLENLVWSSVEDNCRRKSCGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRL 1490
Query: 504 SGSTSVTCTLGG---AWSGVPPSCKYVNCGTP-TIHKGSFVLINGTTTY-GSIAQFTCE- 557
GS S TC + G W P C+ ++C P TI G F N T+ + G++ + C
Sbjct: 1491 IGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHT 1550
Query: 558 -PD----YWLNGAEELVC-NRD---GKWSYDIPSCELTS-CPEPEVPSGGYMEAFDYYVH 607
PD + L G + C ++D G WS P C T+ C PEV + + +
Sbjct: 1551 GPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRCISTNKCTAPEVENAIRVPGNRSFFT 1610
Query: 608 ST--INFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTH 665
T I F C+ G ++G + CQ +G W P C + C P + +G L +
Sbjct: 1611 LTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHCSRV-CQPPPEILHGEHTLSHQDNF 1669
Query: 666 L-GSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDR 724
G + YSC +Y L G CT + WS +PRC C D +
Sbjct: 1670 SPGQEVFYSCEPSYDLRGAASLHCTPQGDWSPEAPRCTVKSCDDFL-----------GQL 1718
Query: 725 SHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTCQ 781
HG L+ + ++GA V + C++G+++ G S S C G W+ + P C+
Sbjct: 1719 PHGRVLLPLN--------LQLGAKVSFVCDEGFRLKGRSASHCVLAGMKALWNSSVPVCE 1770
Query: 782 YVDCGNPGRIENGKVT-LPSNATFYGATAFYQCDEN------WELEGVIRRMC----QEN 830
+ C NP I NG+ T P YG Y CD + + L G C Q N
Sbjct: 1771 QIFCPNPPAILNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGESSIRCTSDPQGN 1830
Query: 831 GTWSLEPPICK---EITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTR 887
G WS P C+ CP P +I+ G + S G Y C+ GY L G
Sbjct: 1831 GVWSSPAPRCELSVPAACPHPP-KIQNGHYIGGHVSLYLPGMTISYICDPGYLLVGKGFI 1889
Query: 888 TCISKGQWNGTVPVCIPIDCRSPGNIEN-GKIVISNGSTLFGSSVEYYCLSQYQRVGPFL 946
C +G W+ C ++C P + K + +G V C Y G
Sbjct: 1890 FCTDQGIWSQLDHYCKEVNCSFPLFMNGISKELEMKKVYHYGDYVTLKCEDGYTLEGSPW 1949
Query: 947 RKCLDDGRWSGEEPSCELATNEAVDSGT 974
+C D RW C T++A+ GT
Sbjct: 1950 SQCQADDRWDPPLAKCTSRTHDALIVGT 1977
Score = 188 bits (457), Expect = 1e-46
Identities = 173/666 (25%), Positives = 262/666 (39%), Gaps = 79/666 (11%)
Query: 353 CGSPDKLLNTTILGNDYDV---GSRIVYKC---PE---GHMLLGDKSRHCKKD----GFW 399
C SP + N G +V G + Y C P+ L+G+ + C D G W
Sbjct: 421 CPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVW 480
Query: 400 SGAPPSCKYV-NCGGLTPIEDGDVALIDNRTTH--GARALYSCRENFTLVGNP-ERTCGD 455
S P C + +C + N + G Y CR + G P TC D
Sbjct: 481 SSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEY--YGRPFSITCLD 538
Query: 456 EGIWDGEAPRCLFDWCPDPPAVSNASV-TVNGHKAGSLASYTCENGHILSGSTSVTCTLG 514
+W C C PP N V + + GS +Y+C GH L G +S C L
Sbjct: 539 NLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILS 598
Query: 515 GA---WSGVPPSCKYVNCGTP-TIHKGSFVLINGTTT-YGSIAQFTCEPD------YWLN 563
G WS PP C+ + CG P TI G F+ N YGS+ + C P + L
Sbjct: 599 GNAAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELV 658
Query: 564 GAEELVC--NRD--GKWSYDIPSCELTS-CPEPEVPSGGYMEAFD--YYVHSTINFHCEA 616
G + C N D G WS P C + + C P V +G + + ++ + F C+
Sbjct: 659 GEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQP 718
Query: 617 GHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHL-GSVIQYSCT 675
G + G + CQ +W + P+C + C P + + + G + YSC
Sbjct: 719 GFVMKGPRRVKCQALNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCE 777
Query: 676 TNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSD 735
Y L G CT + WS ++P CE C D + +G L +
Sbjct: 778 PGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDFM-----------GQLLNGRVLFPVN- 825
Query: 736 NRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTCQYVDCGNPGRIE 792
++GA V + C++G+++ G S S C G W+ + P C+ + C +P I
Sbjct: 826 -------LQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIP 878
Query: 793 NGKVT-LPSNATFYGATAFYQCD------ENWELEGVIRRMC----QENGTWSLEPPICK 841
NG+ T P +G Y CD +++L G C Q NG WS P C
Sbjct: 879 NGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCG 938
Query: 842 EI-TCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVP 900
+ C P + A S IG Y+C Y + TC+ W+
Sbjct: 939 ILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGRPFSI-TCLDNLVWSSPKD 997
Query: 901 VCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDG---RWSG 957
VC C++P + NG + + + GS + Y C + ++ +G +C+ G WS
Sbjct: 998 VCKRKSCKTPPDPVNGMVHVITDIQV-GSRINYSCTTGHRLIGHSSAECILSGNTAHWST 1056
Query: 958 EEPSCE 963
+ P C+
Sbjct: 1057 KPPICQ 1062
Score = 169 bits (411), Expect = 5e-41
Identities = 135/509 (26%), Positives = 209/509 (41%), Gaps = 59/509 (11%)
Query: 490 GSLASYTCENGHILSGST-SVTCTLGGAWSGVPPSCKYVNCGTPTIHKGSFVLINGTTTY 548
G+ +Y C G+ SG S+ C W+G C+ +C P V + +
Sbjct: 66 GTYLNYECRPGY--SGRPFSIICLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKGIQF 123
Query: 549 GSIAQFTCEPDYWLNGAEELVCNRDGK---WSYDIPSCELTSCP-EPEVPSGGYMEAF-- 602
GS +++C Y L G+ C G W + P C+ C P + +G ++
Sbjct: 124 GSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTIANGDFISTNRE 183
Query: 603 DYYVHSTINFHCEAGH------KLIGEPNLVC----QQDGEWSGDSPTCEYIDCGKLPTL 652
+++ S + + C G +L+GEP++ C Q G WSG +P C + P +
Sbjct: 184 NFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNV 243
Query: 653 PYGTMELLNGTTH-LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIV 711
G + N + L V+++ C + + GP R C +W P C + C P
Sbjct: 244 ENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRV-CQPP-- 300
Query: 712 AEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNG 771
D H R DN + G V Y CE GY + G + C G
Sbjct: 301 ----------PDVLHAERTQRDKDN------FSPGQEVFYSCEPGYDLRGAASMRCTPQG 344
Query: 772 QWSGTTPTCQYVDCGN-PGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQEN 830
WS PTC+ C + G++ NG+V P N GA + CDE ++L+G C
Sbjct: 345 DWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQL-GAKVDFVCDEGFQLKGSSASYCVLA 403
Query: 831 GT---WSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCE----RG--YNL 881
G W+ P+C++I CP P I G G +Y C+ RG ++L
Sbjct: 404 GMESLWNSSVPVCEQIFCPSPPV-IPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDL 462
Query: 882 KGHQTRTCIS----KGQWNGTVPVC-IPIDCRSPGNIENGKIVISNGSTLF--GSSVEYY 934
G T C S G W+ P C I C++P + K+ ++ F G+S++Y
Sbjct: 463 IGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYE 522
Query: 935 CLSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
C +Y PF CLD+ WS + C+
Sbjct: 523 CRPEYYG-RPFSITCLDNLVWSSPKDVCK 550
Score = 101 bits (243), Expect = 1e-20
Identities = 80/316 (25%), Positives = 124/316 (39%), Gaps = 42/316 (13%)
Query: 666 LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRS 725
+G+ + Y C Y P C + W+ + RC C +P +V V
Sbjct: 65 IGTYLNYECRPGYS-GRPFSIICLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKG--- 120
Query: 726 HGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTCQY 782
+ G+ +KY C KGY++IG S +TC +G W TP C
Sbjct: 121 -----------------IQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDR 163
Query: 783 VDCGNPGRIENGKVTLPSNATF-YGATAFYQCDEN------WELEGVIRRMCQEN----G 831
+ CG P I NG + F YG+ Y+C+ +EL G C N G
Sbjct: 164 IPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVG 223
Query: 832 TWSLEPPICKEITCPDPSAQIKAGSGLLVV--TSTLSIGGEAHYQCERGYNLKGHQTRTC 889
WS P C P+ +G+LV S S+ ++C+ G+ +KG + C
Sbjct: 224 IWSGPAPQC---IIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKC 280
Query: 890 ISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLF-GSSVEYYCLSQYQRVGPFLRK 948
+ +W +P C + C+ P ++ + + + G V Y C Y G +
Sbjct: 281 QALNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMR 339
Query: 949 CLDDGRWSGEEPSCEL 964
C G WS P+CE+
Sbjct: 340 CTPQGDWSPAAPTCEV 355
Score = 44.0 bits (99), Expect = 0.003
Identities = 17/42 (40%), Positives = 24/42 (57%)
Query: 17 NEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
+++N G Y C+ GY+L GA CT +GDW+ E P C
Sbjct: 1212 HQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGDWSPEAPRC 1253
Score = 42.7 bits (96), Expect = 0.007
Identities = 18/57 (31%), Positives = 28/57 (49%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C P + ++ +++N G Y C+ Y+L GA CT +GDW+ E P C
Sbjct: 1650 CQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCTPQGDWSPEAPRC 1706
Score = 42.3 bits (95), Expect = 0.009
Identities = 19/57 (33%), Positives = 28/57 (49%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C P +A + +++N G Y C+ GY+L GA CT +GDW+ P C
Sbjct: 297 CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTC 353
Score = 42.3 bits (95), Expect = 0.009
Identities = 19/57 (33%), Positives = 28/57 (49%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C P +A + +++N G Y C+ GY+L GA CT +GDW+ P C
Sbjct: 747 CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTC 803
Score = 37.5 bits (83), Expect = 0.26
Identities = 20/60 (33%), Positives = 27/60 (45%), Gaps = 5/60 (8%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGD---WTLEPPFC 58
C +P P N V + + I G+ Y C +GY L G+ C + GD W E P C
Sbjct: 104 CRNPPDPVNGMVHVI--KGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPIC 161
Score = 37.5 bits (83), Expect = 0.26
Identities = 20/60 (33%), Positives = 27/60 (45%), Gaps = 5/60 (8%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGD---WTLEPPFC 58
C P P N V + + I G+ Y C G+ L G EC L G+ W+ +PP C
Sbjct: 554 CKTPPDPVNGMVHVITD--IQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPIC 611
Score = 37.5 bits (83), Expect = 0.26
Identities = 20/60 (33%), Positives = 27/60 (45%), Gaps = 5/60 (8%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGD---WTLEPPFC 58
C P P N V + + I G+ Y C G+ L G EC L G+ W+ +PP C
Sbjct: 1004 CKTPPDPVNGMVHVITD--IQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPIC 1061
Score = 37.5 bits (83), Expect = 0.26
Identities = 19/60 (31%), Positives = 27/60 (45%), Gaps = 5/60 (8%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGD---WTLEPPFC 58
CG P P N V I + G+ Y C+EG+ L G+ C + G+ W + P C
Sbjct: 1457 CGPPPEPFNGMVHINTDTQF--GSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPIC 1514
>AL691452-2|CAI16725.1| 2039|Homo sapiens complement component (3b/4b)
receptor 1 (Knops blood group) protein.
Length = 2039
Score = 234 bits (573), Expect = 1e-60
Identities = 194/665 (29%), Positives = 275/665 (41%), Gaps = 78/665 (11%)
Query: 352 TCGSPDKLLNTTI-LGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDG---FWSGAPPSCK 407
+C +P +N + + D VGSRI Y C GH L+G S C G WS PP C+
Sbjct: 553 SCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQ 612
Query: 408 YVNCGGLTPIEDGDVALIDNRTTH-GARALYSC------RENFTLVGNPERTC--GDE-- 456
+ CG I +GD + H G+ Y C R+ F LVG P C D+
Sbjct: 613 RIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQV 672
Query: 457 GIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGSL---ASYTCENGHILSGSTSVTCTL 513
GIW G AP+C+ PP V N + + SL + C+ G ++ G V C
Sbjct: 673 GIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQA 732
Query: 514 GGAWSGVPPSCKYVNCGTP--TIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCN 571
W PSC V C P +H + G ++CEP Y L GA + C
Sbjct: 733 LNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCT 791
Query: 572 RDGKWSYDIPSCELTSCPE--PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQ 629
G WS P+CE+ SC + ++ +G + + + + ++F C+ G +L G C
Sbjct: 792 PQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCV 851
Query: 630 QDGE---WSGDSPTCEYIDCGKLPTLPYG--TMELLNGTTHLGSVIQYSCT------TNY 678
G W+ P CE I C P +P G T + L G + Y+C T++
Sbjct: 852 LAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLE-VFPFGKAVNYTCDPHPDRGTSF 910
Query: 679 RLVGPVRRTCTEEFQ----WSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTS 734
L+G CT + Q WS +PRC + G+ ++ H L
Sbjct: 911 DLIGESTIRCTSDPQGNGVWSSPAPRC----------------GILGHCQAPDHFLFAKL 954
Query: 735 DNRDVGNTYRIGALVKYRCEKGYKVIGESLS-TCEDNGQWSGTTPTCQYVDCGNPGRIEN 793
+ + + IG +KY C Y G S TC DN WS C+ C P N
Sbjct: 955 KTQTNASDFPIGTSLKYECRPEY--YGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVN 1012
Query: 794 GKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGT---WSLEPPICKEITCPDPSA 850
G V + ++ G+ Y C L G C +G WS +PPIC+ I C P
Sbjct: 1013 GMVHVITDIQV-GSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPCGLPPT 1071
Query: 851 QIKAGSGLLVVTSTLSIGGEAHYQCERG------YNLKGHQTRTCISK----GQWNGTVP 900
I G + G Y+C G + L G + C S G W+G P
Sbjct: 1072 -IANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAP 1130
Query: 901 VC-IPIDCRSPGNIENGKIVISNGSTLFGSS--VEYYCLSQYQRVGPFLRKCLDDGRWSG 957
C IP C +P N+ENG I++S+ +LF + VE+ C + GP KC +W
Sbjct: 1131 QCIIPNKC-TPPNVENG-ILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEP 1188
Query: 958 EEPSC 962
E PSC
Sbjct: 1189 ELPSC 1193
Score = 227 bits (555), Expect = 2e-58
Identities = 187/662 (28%), Positives = 274/662 (41%), Gaps = 69/662 (10%)
Query: 352 TCGSPDKLLNTTI-LGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDG---FWSGAPPSCK 407
+C +P +N + + D VGSRI Y C GH L+G S C G WS PP C+
Sbjct: 1003 SCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQ 1062
Query: 408 YVNCGGLTPIEDGDVALIDNRTTH-GARALYSC------RENFTLVGNPERTC--GDE-- 456
+ CG I +GD + H G+ Y C R+ F LVG P C D+
Sbjct: 1063 RIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQV 1122
Query: 457 GIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGSL---ASYTCENGHILSGSTSVTCTL 513
GIW G AP+C+ PP V N + + SL + C+ G ++ G V C
Sbjct: 1123 GIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQA 1182
Query: 514 GGAWSGVPPSCKYVNCGTPTIHKGSFVLINGTT-TYGSIAQFTCEPDYWLNGAEELVCNR 572
W PSC V P I G + + G ++CEP Y L GA L C
Sbjct: 1183 LNKWEPELPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTP 1242
Query: 573 DGKWSYDIPSCELTSCPE--PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQ 630
G WS + P C + SC + ++P G + + + + ++F C+ G +L G C
Sbjct: 1243 QGDWSPEAPRCAVKSCDDFLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCVL 1302
Query: 631 DGE---WSGDSPTCEYIDCGKLPTLPYGT-MELLNGTTHLGSVIQYSCTTN------YRL 680
G W+ P CE+I C P + G +G G I Y+C + + L
Sbjct: 1303 VGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNL 1362
Query: 681 VGPVRRTCTEEFQ----WSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDN 736
+G CT + WS +PRCE ++ ++ T I +D
Sbjct: 1363 IGESTIRCTSDPHGNGVWSSPAPRCE--------LSVRAGHCKTPEQFPFASPTIPINDF 1414
Query: 737 RDVGNTYRIGALVKYRCEKGYKVIGESLS-TCEDNGQWSGTTPTCQYVDCGNPGRIENGK 795
+ +G + Y C GY G+ S +C +N WS C+ CG P NG
Sbjct: 1415 E-----FPVGTSLNYECRPGY--FGKMFSISCLENLVWSSVEDNCRRKSCGPPPEPFNGM 1467
Query: 796 VTLPSNATFYGATAFYQCDENWELEGVIRRMCQENG---TWSLEPPICKEITCPDPSAQI 852
V + ++ T +G+T Y C+E + L G C +G TW + PIC+ I+C +P I
Sbjct: 1468 VHINTD-TQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISC-EPPPTI 1525
Query: 853 KAGSGLLVVTSTLSIGGEAHYQCERG------YNLKGHQTRTCISK----GQWNGTVPVC 902
G ++ G YQC G + L G ++ C SK G W+ P C
Sbjct: 1526 SNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRC 1585
Query: 903 IPID-CRSPGNIENGKIVISNGSTL-FGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEP 960
I + C +P +EN V N S + + C + VG +C +GRW + P
Sbjct: 1586 ISTNKCTAP-EVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLP 1644
Query: 961 SC 962
C
Sbjct: 1645 HC 1646
Score = 224 bits (547), Expect = 2e-57
Identities = 175/645 (27%), Positives = 261/645 (40%), Gaps = 74/645 (11%)
Query: 368 DYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDN 427
++ +G+ + Y+C G+ S C K+ W+GA C+ +C +G V +I
Sbjct: 62 EFPIGTYLNYECRPGYSGR-PFSIICLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKG 120
Query: 428 RTTHGARALYSCRENFTLVGNPERTC---GDEGIWDGEAPRCLFDWCPDPPAVSNA---S 481
G++ YSC + + L+G+ TC GD IWD E P C C PP ++N S
Sbjct: 121 -IQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTITNGDFIS 179
Query: 482 VTVNGHKAGSLASYTCENG------HILSGSTSVTCTLG----GAWSGVPPSCKYVN-CG 530
GS+ +Y C G L G S+ CT G WSG P C N C
Sbjct: 180 TNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCT 239
Query: 531 TPTIHKGSFVLINGTT-TYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCP 589
P + G V N + + + +F C+P + + G + C KW ++PSC P
Sbjct: 240 PPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQP 299
Query: 590 EPEV--PSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCG 647
P+V + ++ + + CE G+ L G ++ C G+WS +PTCE C
Sbjct: 300 PPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCD 359
Query: 648 KLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCT---EEFQWSDSSPRCEEI 704
L LG+ + + C ++L G C E W+ S P CE+I
Sbjct: 360 DFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQI 419
Query: 705 RCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCE------KGYK 758
C P V N R G L + G V Y C+ +
Sbjct: 420 FCPSP--------PVIPNGRHTGKPL----------EVFPFGKTVNYTCDPHPDRGTSFD 461
Query: 759 VIGESLSTC----EDNGQWSGTTPTCQYV-DCGNPGRIENGKVTLPSNATFY--GATAFY 811
+IGES C + NG WS P C + C P K+ +NA+ + G + Y
Sbjct: 462 LIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKY 521
Query: 812 QCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEA 871
+C + C +N WS +CK +C P + +G++ V + + +G
Sbjct: 522 ECRPEY-YGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPV---NGMVHVITDIQVGSRI 577
Query: 872 HYQCERGYNLKGHQTRTCISKG---QWNGTVPVCIPIDCRSPGNIENGKIVISNGSTL-F 927
+Y C G+ L GH + CI G W+ P+C I C P I NG + +N +
Sbjct: 578 NYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHY 637
Query: 928 GSSVEYYC------LSQYQRVGPFLRKCL--DD--GRWSGEEPSC 962
GS V Y C ++ VG C DD G WSG P C
Sbjct: 638 GSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQC 682
Score = 221 bits (541), Expect = 8e-57
Identities = 188/665 (28%), Positives = 271/665 (40%), Gaps = 78/665 (11%)
Query: 352 TCGSPDKLLNTTI-LGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDG---FWSGAPPSCK 407
+C +P +N + + GS+I Y C +G+ L+G S C G W P C
Sbjct: 103 SCRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICD 162
Query: 408 YVNCGGLTPIEDGDVALIDNRTTH-GARALYSC------RENFTLVGNPERTC--GDE-- 456
+ CG I +GD + H G+ Y C R+ F LVG P C D+
Sbjct: 163 RIPCGLPPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQV 222
Query: 457 GIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGSL---ASYTCENGHILSGSTSVTCTL 513
GIW G AP+C+ PP V N + + SL + C+ G ++ G V C
Sbjct: 223 GIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQA 282
Query: 514 GGAWSGVPPSCKYVNCGTP--TIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCN 571
W PSC V C P +H + G ++CEP Y L GA + C
Sbjct: 283 LNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCT 341
Query: 572 RDGKWSYDIPSCELTSCPE--PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQ 629
G WS P+CE+ SC + ++ +G + + + + ++F C+ G +L G C
Sbjct: 342 PQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCV 401
Query: 630 QDGE---WSGDSPTCEYIDCGKLPTLPYG--TMELLNGTTHLGSVIQYSCT------TNY 678
G W+ P CE I C P +P G T + L G + Y+C T++
Sbjct: 402 LAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLE-VFPFGKTVNYTCDPHPDRGTSF 460
Query: 679 RLVGPVRRTCTEEFQ----WSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTS 734
L+G CT + Q WS +PRC + G+ ++ H L
Sbjct: 461 DLIGESTIRCTSDPQGNGVWSSPAPRC----------------GILGHCQAPDHFLFAKL 504
Query: 735 DNRDVGNTYRIGALVKYRCEKGYKVIGESLS-TCEDNGQWSGTTPTCQYVDCGNPGRIEN 793
+ + + IG +KY C Y G S TC DN WS C+ C P N
Sbjct: 505 KTQTNASDFPIGTSLKYECRPEY--YGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVN 562
Query: 794 GKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGT---WSLEPPICKEITCPDPSA 850
G V + ++ G+ Y C L G C +G WS +PPIC+ I C P
Sbjct: 563 GMVHVITDIQV-GSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPT 621
Query: 851 QIKAGSGLLVVTSTLSIGGEAHYQCERG------YNLKGHQTRTCISK----GQWNGTVP 900
I G + G Y+C G + L G + C S G W+G P
Sbjct: 622 -IANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAP 680
Query: 901 VC-IPIDCRSPGNIENGKIVISNGSTLFGSS--VEYYCLSQYQRVGPFLRKCLDDGRWSG 957
C IP C +P N+ENG I++S+ +LF + VE+ C + GP KC +W
Sbjct: 681 QCIIPNKC-TPPNVENG-ILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEP 738
Query: 958 EEPSC 962
E PSC
Sbjct: 739 ELPSC 743
Score = 205 bits (501), Expect = 6e-52
Identities = 178/668 (26%), Positives = 269/668 (40%), Gaps = 72/668 (10%)
Query: 353 CGSPDKLL----NTTILGNDYDVGSRIVYKC-PEGHMLLGDKSRHCKKDGFWSGAPPSCK 407
C +PD L T +D+ +G+ + Y+C PE + S C + WS CK
Sbjct: 943 CQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGR--PFSITCLDNLVWSSPKDVCK 1000
Query: 408 YVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTC---GDEGIWDGEAP 464
+C +G V +I + G+R YSC L+G+ C G+ W + P
Sbjct: 1001 RKSCKTPPDPVNGMVHVITDIQV-GSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPP 1059
Query: 465 RCLFDWCPDPPAVSNAS-VTVNGHKA--GSLASYTCENGHI------LSGSTSVTCTLG- 514
C C PP ++N ++ N GS+ +Y C G L G S+ CT
Sbjct: 1060 ICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSND 1119
Query: 515 ---GAWSGVPPSCKYVN-CGTPTIHKGSFVLINGTT-TYGSIAQFTCEPDYWLNGAEELV 569
G WSG P C N C P + G V N + + + +F C+P + + G +
Sbjct: 1120 DQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVK 1179
Query: 570 CNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAF--DYYVHSTINFHCEAGHKLIGEPNLV 627
C KW ++PSC P PE+ G + + ++ + + CE G+ L G +L
Sbjct: 1180 CQALNKWEPELPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLH 1239
Query: 628 CQQDGEWSGDSPTCEYIDCGK-LPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRR 686
C G+WS ++P C C L LP+G + L LG+ + + C +RL G
Sbjct: 1240 CTPQGDWSPEAPRCAVKSCDDFLGQLPHGRV-LFPLNLQLGAKVSFVCDEGFRLKGSSVS 1298
Query: 687 TCT---EEFQWSDSSPRCEEIRCSDP-IVAEKSIVSVTGNDRSHGHTLIRTSD-NRDVGN 741
C W++S P CE I C +P + D +G + T D + D G
Sbjct: 1299 HCVLVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGM 1358
Query: 742 TYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYV----DCGNPGRIENGKVT 797
T+ + RC S NG WS P C+ C P + T
Sbjct: 1359 TFNLIGESTIRCT----------SDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPT 1408
Query: 798 LPSNATFY--GATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAG 855
+P N + G + Y+C + + C EN WS C+ +C P
Sbjct: 1409 IPINDFEFPVGTSLNYECRPGY-FGKMFSISCLENLVWSSVEDNCRRKSCGPPPEPF--- 1464
Query: 856 SGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQ---WNGTVPVCIPIDCRSPGN 912
+G++ + + G +Y C G+ L G + TC+ G W+ P+C I C P
Sbjct: 1465 NGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPT 1524
Query: 913 IENGKIVISNGSTLF--GSSVEYYCLS------QYQRVGPFLRKCL--DD--GRWSGEEP 960
I NG SN T F G+ V Y C + ++ VG C DD G WS P
Sbjct: 1525 ISNGDF-YSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPP 1583
Query: 961 SCELATNE 968
C ++TN+
Sbjct: 1584 RC-ISTNK 1590
Score = 200 bits (488), Expect = 2e-50
Identities = 170/650 (26%), Positives = 256/650 (39%), Gaps = 79/650 (12%)
Query: 371 VGSRIVYKCPEGHMLLGDKSRHCKKDGF---WSGAPPSCKYVNCGGLTPIEDG-DVALID 426
+G+++ + C EG L G HC G W+ + P C+++ C I +G
Sbjct: 1278 LGAKVSFVCDEGFRLKGSSVSHCVLVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPS 1337
Query: 427 NRTTHGARALYSCREN------FTLVGNPERTCGDE----GIWDGEAPRCLFD----WCP 472
+G Y+C + F L+G C + G+W APRC C
Sbjct: 1338 GDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTSDPHGNGVWSSPAPRCELSVRAGHCK 1397
Query: 473 DPPAVSNASVTV--NGHK--AGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVN 528
P AS T+ N + G+ +Y C G+ S++C WS V +C+ +
Sbjct: 1398 TPEQFPFASPTIPINDFEFPVGTSLNYECRPGYF-GKMFSISCLENLVWSSVEDNCRRKS 1456
Query: 529 CGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGK---WSYDIPSCEL 585
CG P V IN T +GS ++C + L G+ C G W P CE+
Sbjct: 1457 CGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEI 1516
Query: 586 TSC-PEPEVPSGGYM--EAFDYYVHSTINFHCEAG------HKLIGEPNLVC----QQDG 632
SC P P + +G + ++ + + + C G +L+GE ++ C Q G
Sbjct: 1517 ISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVG 1576
Query: 633 EWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTH-LGSVIQYSCTTNYRLVGPVRRTCTEE 691
WS P C + P + N + L +I++ C + +VG C
Sbjct: 1577 VWSSPPPRCISTNKCTAPEVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTN 1636
Query: 692 FQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKY 751
+W P C + C P + HG + DN + G V Y
Sbjct: 1637 GRWGPKLPHCSRV-CQPP------------PEILHGEHTLSHQDN------FSPGQEVFY 1677
Query: 752 RCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGN-PGRIENGKVTLPSNATFYGATAF 810
CE Y + G + C G WS P C C + G++ +G+V LP N GA
Sbjct: 1678 SCEPSYDLRGAASLHCTPQGDWSPEAPRCTVKSCDDFLGQLPHGRVLLPLNLQL-GAKVS 1736
Query: 811 YQCDENWELEGVIRRMCQENG---TWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSI 867
+ CDE + L+G C G W+ P+C++I CP+P A I G +
Sbjct: 1737 FVCDEGFRLKGRSASHCVLAGMKALWNSSVPVCEQIFCPNPPA-ILNGRHTGTPFGDIPY 1795
Query: 868 GGEAHYQC----ERG--YNLKGHQTRTCIS----KGQWNGTVPVC---IPIDCRSPGNIE 914
G E Y C +RG +NL G + C S G W+ P C +P C P I+
Sbjct: 1796 GKEISYACDTHPDRGMTFNLIGESSIRCTSDPQGNGVWSSPAPRCELSVPAACPHPPKIQ 1855
Query: 915 NGKIVISNGST-LFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
NG + + S L G ++ Y C Y VG C D G WS + C+
Sbjct: 1856 NGHYIGGHVSLYLPGMTISYICDPGYLLVGKGFIFCTDQGIWSQLDHYCK 1905
Score = 197 bits (480), Expect = 2e-49
Identities = 174/678 (25%), Positives = 274/678 (40%), Gaps = 90/678 (13%)
Query: 345 ICQYLPPTCGSPDKLLNTTILGND---YDVGSRIVYKCPEGH------MLLGDKSRHCKK 395
IC +P CG P + N + + + GS + Y+C G L+G+ S +C
Sbjct: 160 ICDRIP--CGLPPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTS 217
Query: 396 D----GFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRTTHGARAL--YSCRENFTLVGNP 449
+ G WSG P C N +E+G + + DNR+ + + C+ F + G
Sbjct: 218 NDDQVGIWSGPAPQCIIPNKCTPPNVENG-ILVSDNRSLFSLNEVVEFRCQPGFVMKGPR 276
Query: 450 ERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTV---NGHKAGSLASYTCENGHILSGS 506
C W+ E P C C PP V +A T + G Y+CE G+ L G+
Sbjct: 277 RVKCQALNKWEPELPSCS-RVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGA 335
Query: 507 TSVTCTLGGAWSGVPPSCKYVNCGT--PTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNG 564
S+ CT G WS P+C+ +C + G VL G+ F C+ + L G
Sbjct: 336 ASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGR-VLFPVNLQLGAKVDFVCDEGFQLKG 394
Query: 565 AEELVC---NRDGKWSYDIPSCELTSCPEPEV-PSGGY----MEAFDYYVHSTINFHCE- 615
+ C + W+ +P CE CP P V P+G + +E F + T+N+ C+
Sbjct: 395 SSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPF--GKTVNYTCDP 452
Query: 616 -----AGHKLIGEPNLVCQQD----GEWSGDSPTCEYIDCGKLPT-LPYGTMELLNGTTH 665
LIGE + C D G WS +P C + + P + ++ +
Sbjct: 453 HPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASD 512
Query: 666 --LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGND 723
+G+ ++Y C Y P TC + WS C+ C P D
Sbjct: 513 FPIGTSLKYECRPEY-YGRPFSITCLDNLVWSSPKDVCKRKSCKTP------------PD 559
Query: 724 RSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTC 780
+G + T D+ ++G+ + Y C G+++IG S + C +G WS P C
Sbjct: 560 PVNGMVHVIT----DI----QVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPIC 611
Query: 781 QYVDCGNPGRIENGKVTLPSNATF-YGATAFYQCDEN------WELEGVIRRMCQEN--- 830
Q + CG P I NG + F YG+ Y+C+ +EL G C N
Sbjct: 612 QRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQ 671
Query: 831 -GTWSLEPPICKEITCPDPSAQIKAGSGLLVVT--STLSIGGEAHYQCERGYNLKGHQTR 887
G WS P C P+ +G+LV S S+ ++C+ G+ +KG +
Sbjct: 672 VGIWSGPAPQC---IIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRV 728
Query: 888 TCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLF-GSSVEYYCLSQYQRVGPFL 946
C + +W +P C + C+ P ++ + + + G V Y C Y G
Sbjct: 729 KCQALNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAAS 787
Query: 947 RKCLDDGRWSGEEPSCEL 964
+C G WS P+CE+
Sbjct: 788 MRCTPQGDWSPAAPTCEV 805
Score = 196 bits (479), Expect = 3e-49
Identities = 181/674 (26%), Positives = 263/674 (39%), Gaps = 82/674 (12%)
Query: 353 CGSPDKLLNTTILGNDYDV---GSRIVYKC---PE---GHMLLGDKSRHCKKD----GFW 399
C SP + N G +V G + Y C P+ L+G+ + C D G W
Sbjct: 871 CPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVW 930
Query: 400 SGAPPSCKYV-NCGGLTPIEDGDVALIDNRTTH--GARALYSCRENFTLVGNP-ERTCGD 455
S P C + +C + N + G Y CR + G P TC D
Sbjct: 931 SSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEY--YGRPFSITCLD 988
Query: 456 EGIWDGEAPRCLFDWCPDPPAVSNASV-TVNGHKAGSLASYTCENGHILSGSTSVTCTLG 514
+W C C PP N V + + GS +Y+C GH L G +S C L
Sbjct: 989 NLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILS 1048
Query: 515 GA---WSGVPPSCKYVNCGTP-TIHKGSFVLINGTTT-YGSIAQFTCEPD------YWLN 563
G WS PP C+ + CG P TI G F+ N YGS+ + C + L
Sbjct: 1049 GNTAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELV 1108
Query: 564 GAEELVC--NRD--GKWSYDIPSCELTS-CPEPEVPSGGYMEAFD--YYVHSTINFHCEA 616
G + C N D G WS P C + + C P V +G + + ++ + F C+
Sbjct: 1109 GEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQP 1168
Query: 617 GHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHL-GSVIQYSCT 675
G + G + CQ +W + P+C + C P + +G + G + YSC
Sbjct: 1169 GFVMKGPRRVKCQALNKWEPELPSCSRV-CQPPPEILHGEHTPSHQDNFSPGQEVFYSCE 1227
Query: 676 TNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSD 735
Y L G CT + WS +PRC C D + HG L +
Sbjct: 1228 PGYDLRGAASLHCTPQGDWSPEAPRCAVKSCDDFL-----------GQLPHGRVLFPLN- 1275
Query: 736 NRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTCQYVDCGNPGRIE 792
++GA V + C++G+++ G S+S C G W+ + P C+++ C NP I
Sbjct: 1276 -------LQLGAKVSFVCDEGFRLKGSSVSHCVLVGMRSLWNNSVPVCEHIFCPNPPAIL 1328
Query: 793 NGKVT-LPSNATFYGATAFYQCDEN------WELEGVIRRMCQE----NGTWSLEPPICK 841
NG+ T PS YG Y CD + + L G C NG WS P C+
Sbjct: 1329 NGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTSDPHGNGVWSSPAPRCE 1388
Query: 842 EIT----CPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNG 897
C P A + + +G +Y+C GY K +C+ W+
Sbjct: 1389 LSVRAGHCKTPEQFPFASPTIPINDFEFPVGTSLNYECRPGYFGKMFSI-SCLENLVWSS 1447
Query: 898 TVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGR--- 954
C C P NG + I N T FGS+V Y C ++ +G CL G
Sbjct: 1448 VEDNCRRKSCGPPPEPFNGMVHI-NTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVT 1506
Query: 955 WSGEEPSCELATNE 968
W + P CE+ + E
Sbjct: 1507 WDKKAPICEIISCE 1520
Score = 196 bits (477), Expect = 5e-49
Identities = 186/688 (27%), Positives = 271/688 (39%), Gaps = 83/688 (12%)
Query: 345 ICQYLPPTCGSPDKLLNTTILGN---DYDVGSRIVYKC---PEGHM---LLGDKSRHCKK 395
+C+++ C +P +LN G D G I Y C P+ M L+G+ + C
Sbjct: 1315 VCEHI--FCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTS 1372
Query: 396 D----GFWSGAPPSCKY-VNCGGLT-----PIEDGDVALIDNRTTHGARALYSCRENFTL 445
D G WS P C+ V G P + + D G Y CR +
Sbjct: 1373 DPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDFEFPVGTSLNYECRPGY-- 1430
Query: 446 VGNP-ERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGH-KAGSLASYTCENGHIL 503
G +C + +W C C PP N V +N + GS +Y+C G L
Sbjct: 1431 FGKMFSISCLENLVWSSVEDNCRRKSCGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRL 1490
Query: 504 SGSTSVTCTLGG---AWSGVPPSCKYVNCGTP-TIHKGSFVLINGTTTY-GSIAQFTCE- 557
GS S TC + G W P C+ ++C P TI G F N T+ + G++ + C
Sbjct: 1491 IGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHT 1550
Query: 558 -PD----YWLNGAEELVC-NRD---GKWSYDIPSCELTS-CPEPEVPSGGYMEAFDYYVH 607
PD + L G + C ++D G WS P C T+ C PEV + + +
Sbjct: 1551 GPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRCISTNKCTAPEVENAIRVPGNRSFFT 1610
Query: 608 ST--INFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTH 665
T I F C+ G ++G + CQ +G W P C + C P + +G L +
Sbjct: 1611 LTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHCSRV-CQPPPEILHGEHTLSHQDNF 1669
Query: 666 L-GSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDR 724
G + YSC +Y L G CT + WS +PRC C D +
Sbjct: 1670 SPGQEVFYSCEPSYDLRGAASLHCTPQGDWSPEAPRCTVKSCDDFL-----------GQL 1718
Query: 725 SHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTCQ 781
HG L+ + ++GA V + C++G+++ G S S C G W+ + P C+
Sbjct: 1719 PHGRVLLPLN--------LQLGAKVSFVCDEGFRLKGRSASHCVLAGMKALWNSSVPVCE 1770
Query: 782 YVDCGNPGRIENGKVT-LPSNATFYGATAFYQCDEN------WELEGVIRRMC----QEN 830
+ C NP I NG+ T P YG Y CD + + L G C Q N
Sbjct: 1771 QIFCPNPPAILNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGESSIRCTSDPQGN 1830
Query: 831 GTWSLEPPICK---EITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTR 887
G WS P C+ CP P +I+ G + S G Y C+ GY L G
Sbjct: 1831 GVWSSPAPRCELSVPAACPHPP-KIQNGHYIGGHVSLYLPGMTISYICDPGYLLVGKGFI 1889
Query: 888 TCISKGQWNGTVPVCIPIDCRSPGNIEN-GKIVISNGSTLFGSSVEYYCLSQYQRVGPFL 946
C +G W+ C ++C P + K + +G V C Y G
Sbjct: 1890 FCTDQGIWSQLDHYCKEVNCSFPLFMNGISKELEMKKVYHYGDYVTLKCEDGYTLEGSPW 1949
Query: 947 RKCLDDGRWSGEEPSCELATNEAVDSGT 974
+C D RW C T++A+ GT
Sbjct: 1950 SQCQADDRWDPPLAKCTSRTHDALIVGT 1977
Score = 188 bits (457), Expect = 1e-46
Identities = 173/666 (25%), Positives = 262/666 (39%), Gaps = 79/666 (11%)
Query: 353 CGSPDKLLNTTILGNDYDV---GSRIVYKC---PE---GHMLLGDKSRHCKKD----GFW 399
C SP + N G +V G + Y C P+ L+G+ + C D G W
Sbjct: 421 CPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVW 480
Query: 400 SGAPPSCKYV-NCGGLTPIEDGDVALIDNRTTH--GARALYSCRENFTLVGNP-ERTCGD 455
S P C + +C + N + G Y CR + G P TC D
Sbjct: 481 SSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEY--YGRPFSITCLD 538
Query: 456 EGIWDGEAPRCLFDWCPDPPAVSNASV-TVNGHKAGSLASYTCENGHILSGSTSVTCTLG 514
+W C C PP N V + + GS +Y+C GH L G +S C L
Sbjct: 539 NLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILS 598
Query: 515 GA---WSGVPPSCKYVNCGTP-TIHKGSFVLINGTTT-YGSIAQFTCEPD------YWLN 563
G WS PP C+ + CG P TI G F+ N YGS+ + C P + L
Sbjct: 599 GNAAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELV 658
Query: 564 GAEELVC--NRD--GKWSYDIPSCELTS-CPEPEVPSGGYMEAFD--YYVHSTINFHCEA 616
G + C N D G WS P C + + C P V +G + + ++ + F C+
Sbjct: 659 GEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQP 718
Query: 617 GHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHL-GSVIQYSCT 675
G + G + CQ +W + P+C + C P + + + G + YSC
Sbjct: 719 GFVMKGPRRVKCQALNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCE 777
Query: 676 TNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSD 735
Y L G CT + WS ++P CE C D + +G L +
Sbjct: 778 PGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDFM-----------GQLLNGRVLFPVN- 825
Query: 736 NRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTCQYVDCGNPGRIE 792
++GA V + C++G+++ G S S C G W+ + P C+ + C +P I
Sbjct: 826 -------LQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIP 878
Query: 793 NGKVT-LPSNATFYGATAFYQCD------ENWELEGVIRRMC----QENGTWSLEPPICK 841
NG+ T P +G Y CD +++L G C Q NG WS P C
Sbjct: 879 NGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCG 938
Query: 842 EI-TCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVP 900
+ C P + A S IG Y+C Y + TC+ W+
Sbjct: 939 ILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGRPFSI-TCLDNLVWSSPKD 997
Query: 901 VCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDG---RWSG 957
VC C++P + NG + + + GS + Y C + ++ +G +C+ G WS
Sbjct: 998 VCKRKSCKTPPDPVNGMVHVITDIQV-GSRINYSCTTGHRLIGHSSAECILSGNTAHWST 1056
Query: 958 EEPSCE 963
+ P C+
Sbjct: 1057 KPPICQ 1062
Score = 169 bits (411), Expect = 5e-41
Identities = 135/509 (26%), Positives = 209/509 (41%), Gaps = 59/509 (11%)
Query: 490 GSLASYTCENGHILSGST-SVTCTLGGAWSGVPPSCKYVNCGTPTIHKGSFVLINGTTTY 548
G+ +Y C G+ SG S+ C W+G C+ +C P V + +
Sbjct: 66 GTYLNYECRPGY--SGRPFSIICLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKGIQF 123
Query: 549 GSIAQFTCEPDYWLNGAEELVCNRDGK---WSYDIPSCELTSCP-EPEVPSGGYMEAF-- 602
GS +++C Y L G+ C G W + P C+ C P + +G ++
Sbjct: 124 GSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTITNGDFISTNRE 183
Query: 603 DYYVHSTINFHCEAGH------KLIGEPNLVC----QQDGEWSGDSPTCEYIDCGKLPTL 652
+++ S + + C G +L+GEP++ C Q G WSG +P C + P +
Sbjct: 184 NFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNV 243
Query: 653 PYGTMELLNGTTH-LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIV 711
G + N + L V+++ C + + GP R C +W P C + C P
Sbjct: 244 ENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRV-CQPP-- 300
Query: 712 AEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNG 771
D H R DN + G V Y CE GY + G + C G
Sbjct: 301 ----------PDVLHAERTQRDKDN------FSPGQEVFYSCEPGYDLRGAASMRCTPQG 344
Query: 772 QWSGTTPTCQYVDCGN-PGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQEN 830
WS PTC+ C + G++ NG+V P N GA + CDE ++L+G C
Sbjct: 345 DWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQL-GAKVDFVCDEGFQLKGSSASYCVLA 403
Query: 831 GT---WSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCE----RG--YNL 881
G W+ P+C++I CP P I G G +Y C+ RG ++L
Sbjct: 404 GMESLWNSSVPVCEQIFCPSPPV-IPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDL 462
Query: 882 KGHQTRTCIS----KGQWNGTVPVC-IPIDCRSPGNIENGKIVISNGSTLF--GSSVEYY 934
G T C S G W+ P C I C++P + K+ ++ F G+S++Y
Sbjct: 463 IGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYE 522
Query: 935 CLSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
C +Y PF CLD+ WS + C+
Sbjct: 523 CRPEYYG-RPFSITCLDNLVWSSPKDVCK 550
Score = 101 bits (243), Expect = 1e-20
Identities = 80/316 (25%), Positives = 124/316 (39%), Gaps = 42/316 (13%)
Query: 666 LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRS 725
+G+ + Y C Y P C + W+ + RC C +P +V V
Sbjct: 65 IGTYLNYECRPGYS-GRPFSIICLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKG--- 120
Query: 726 HGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTCQY 782
+ G+ +KY C KGY++IG S +TC +G W TP C
Sbjct: 121 -----------------IQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDR 163
Query: 783 VDCGNPGRIENGKVTLPSNATF-YGATAFYQCDEN------WELEGVIRRMCQEN----G 831
+ CG P I NG + F YG+ Y+C+ +EL G C N G
Sbjct: 164 IPCGLPPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVG 223
Query: 832 TWSLEPPICKEITCPDPSAQIKAGSGLLVV--TSTLSIGGEAHYQCERGYNLKGHQTRTC 889
WS P C P+ +G+LV S S+ ++C+ G+ +KG + C
Sbjct: 224 IWSGPAPQC---IIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKC 280
Query: 890 ISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLF-GSSVEYYCLSQYQRVGPFLRK 948
+ +W +P C + C+ P ++ + + + G V Y C Y G +
Sbjct: 281 QALNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMR 339
Query: 949 CLDDGRWSGEEPSCEL 964
C G WS P+CE+
Sbjct: 340 CTPQGDWSPAAPTCEV 355
Score = 44.0 bits (99), Expect = 0.003
Identities = 17/42 (40%), Positives = 24/42 (57%)
Query: 17 NEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
+++N G Y C+ GY+L GA CT +GDW+ E P C
Sbjct: 1212 HQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGDWSPEAPRC 1253
Score = 42.7 bits (96), Expect = 0.007
Identities = 18/57 (31%), Positives = 28/57 (49%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C P + ++ +++N G Y C+ Y+L GA CT +GDW+ E P C
Sbjct: 1650 CQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCTPQGDWSPEAPRC 1706
Score = 42.3 bits (95), Expect = 0.009
Identities = 19/57 (33%), Positives = 28/57 (49%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C P +A + +++N G Y C+ GY+L GA CT +GDW+ P C
Sbjct: 297 CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTC 353
Score = 42.3 bits (95), Expect = 0.009
Identities = 19/57 (33%), Positives = 28/57 (49%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C P +A + +++N G Y C+ GY+L GA CT +GDW+ P C
Sbjct: 747 CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTC 803
Score = 37.5 bits (83), Expect = 0.26
Identities = 20/60 (33%), Positives = 27/60 (45%), Gaps = 5/60 (8%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGD---WTLEPPFC 58
C +P P N V + + I G+ Y C +GY L G+ C + GD W E P C
Sbjct: 104 CRNPPDPVNGMVHVI--KGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPIC 161
Score = 37.5 bits (83), Expect = 0.26
Identities = 20/60 (33%), Positives = 27/60 (45%), Gaps = 5/60 (8%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGD---WTLEPPFC 58
C P P N V + + I G+ Y C G+ L G EC L G+ W+ +PP C
Sbjct: 554 CKTPPDPVNGMVHVITD--IQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPIC 611
Score = 37.5 bits (83), Expect = 0.26
Identities = 20/60 (33%), Positives = 27/60 (45%), Gaps = 5/60 (8%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGD---WTLEPPFC 58
C P P N V + + I G+ Y C G+ L G EC L G+ W+ +PP C
Sbjct: 1004 CKTPPDPVNGMVHVITD--IQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPIC 1061
Score = 37.5 bits (83), Expect = 0.26
Identities = 19/60 (31%), Positives = 27/60 (45%), Gaps = 5/60 (8%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGD---WTLEPPFC 58
CG P P N V I + G+ Y C+EG+ L G+ C + G+ W + P C
Sbjct: 1457 CGPPPEPFNGMVHINTDTQF--GSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPIC 1514
>AL691452-1|CAI16724.1| 2039|Homo sapiens complement component (3b/4b)
receptor 1 (Knops blood group) protein.
Length = 2039
Score = 234 bits (573), Expect = 1e-60
Identities = 194/665 (29%), Positives = 275/665 (41%), Gaps = 78/665 (11%)
Query: 352 TCGSPDKLLNTTI-LGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDG---FWSGAPPSCK 407
+C +P +N + + D VGSRI Y C GH L+G S C G WS PP C+
Sbjct: 553 SCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQ 612
Query: 408 YVNCGGLTPIEDGDVALIDNRTTH-GARALYSC------RENFTLVGNPERTC--GDE-- 456
+ CG I +GD + H G+ Y C R+ F LVG P C D+
Sbjct: 613 RIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQV 672
Query: 457 GIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGSL---ASYTCENGHILSGSTSVTCTL 513
GIW G AP+C+ PP V N + + SL + C+ G ++ G V C
Sbjct: 673 GIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQA 732
Query: 514 GGAWSGVPPSCKYVNCGTP--TIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCN 571
W PSC V C P +H + G ++CEP Y L GA + C
Sbjct: 733 LNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCT 791
Query: 572 RDGKWSYDIPSCELTSCPE--PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQ 629
G WS P+CE+ SC + ++ +G + + + + ++F C+ G +L G C
Sbjct: 792 PQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCV 851
Query: 630 QDGE---WSGDSPTCEYIDCGKLPTLPYG--TMELLNGTTHLGSVIQYSCT------TNY 678
G W+ P CE I C P +P G T + L G + Y+C T++
Sbjct: 852 LAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLE-VFPFGKTVNYTCDPHPDRGTSF 910
Query: 679 RLVGPVRRTCTEEFQ----WSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTS 734
L+G CT + Q WS +PRC + G+ ++ H L
Sbjct: 911 DLIGESTIRCTSDPQGNGVWSSPAPRC----------------GILGHCQAPDHFLFAKL 954
Query: 735 DNRDVGNTYRIGALVKYRCEKGYKVIGESLS-TCEDNGQWSGTTPTCQYVDCGNPGRIEN 793
+ + + IG +KY C Y G S TC DN WS C+ C P N
Sbjct: 955 KTQTNASDFPIGTSLKYECRPEY--YGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVN 1012
Query: 794 GKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGT---WSLEPPICKEITCPDPSA 850
G V + ++ G+ Y C L G C +G WS +PPIC+ I C P
Sbjct: 1013 GMVHVITDIQV-GSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPCGLPPT 1071
Query: 851 QIKAGSGLLVVTSTLSIGGEAHYQCERG------YNLKGHQTRTCISK----GQWNGTVP 900
I G + G Y+C G + L G + C S G W+G P
Sbjct: 1072 -IANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAP 1130
Query: 901 VC-IPIDCRSPGNIENGKIVISNGSTLFGSS--VEYYCLSQYQRVGPFLRKCLDDGRWSG 957
C IP C +P N+ENG I++S+ +LF + VE+ C + GP KC +W
Sbjct: 1131 QCIIPNKC-TPPNVENG-ILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEP 1188
Query: 958 EEPSC 962
E PSC
Sbjct: 1189 ELPSC 1193
Score = 227 bits (555), Expect = 2e-58
Identities = 187/662 (28%), Positives = 274/662 (41%), Gaps = 69/662 (10%)
Query: 352 TCGSPDKLLNTTI-LGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDG---FWSGAPPSCK 407
+C +P +N + + D VGSRI Y C GH L+G S C G WS PP C+
Sbjct: 1003 SCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQ 1062
Query: 408 YVNCGGLTPIEDGDVALIDNRTTH-GARALYSC------RENFTLVGNPERTC--GDE-- 456
+ CG I +GD + H G+ Y C R+ F LVG P C D+
Sbjct: 1063 RIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQV 1122
Query: 457 GIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGSL---ASYTCENGHILSGSTSVTCTL 513
GIW G AP+C+ PP V N + + SL + C+ G ++ G V C
Sbjct: 1123 GIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQA 1182
Query: 514 GGAWSGVPPSCKYVNCGTPTIHKGSFVLINGTT-TYGSIAQFTCEPDYWLNGAEELVCNR 572
W PSC V P I G + + G ++CEP Y L GA L C
Sbjct: 1183 LNKWEPELPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTP 1242
Query: 573 DGKWSYDIPSCELTSCPE--PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQ 630
G WS + P C + SC + ++P G + + + + ++F C+ G +L G C
Sbjct: 1243 QGDWSPEAPRCAVKSCDDFLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCVL 1302
Query: 631 DGE---WSGDSPTCEYIDCGKLPTLPYGT-MELLNGTTHLGSVIQYSCTTN------YRL 680
G W+ P CE+I C P + G +G G I Y+C + + L
Sbjct: 1303 VGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNL 1362
Query: 681 VGPVRRTCTEEFQ----WSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDN 736
+G CT + WS +PRCE ++ ++ T I +D
Sbjct: 1363 IGESTIRCTSDPHGNGVWSSPAPRCE--------LSVRAGHCKTPEQFPFASPTIPINDF 1414
Query: 737 RDVGNTYRIGALVKYRCEKGYKVIGESLS-TCEDNGQWSGTTPTCQYVDCGNPGRIENGK 795
+ +G + Y C GY G+ S +C +N WS C+ CG P NG
Sbjct: 1415 E-----FPVGTSLNYECRPGY--FGKMFSISCLENLVWSSVEDNCRRKSCGPPPEPFNGM 1467
Query: 796 VTLPSNATFYGATAFYQCDENWELEGVIRRMCQENG---TWSLEPPICKEITCPDPSAQI 852
V + ++ T +G+T Y C+E + L G C +G TW + PIC+ I+C +P I
Sbjct: 1468 VHINTD-TQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISC-EPPPTI 1525
Query: 853 KAGSGLLVVTSTLSIGGEAHYQCERG------YNLKGHQTRTCISK----GQWNGTVPVC 902
G ++ G YQC G + L G ++ C SK G W+ P C
Sbjct: 1526 SNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRC 1585
Query: 903 IPID-CRSPGNIENGKIVISNGSTL-FGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEP 960
I + C +P +EN V N S + + C + VG +C +GRW + P
Sbjct: 1586 ISTNKCTAP-EVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLP 1644
Query: 961 SC 962
C
Sbjct: 1645 HC 1646
Score = 224 bits (547), Expect = 2e-57
Identities = 175/645 (27%), Positives = 261/645 (40%), Gaps = 74/645 (11%)
Query: 368 DYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDN 427
++ +G+ + Y+C G+ S C K+ W+GA C+ +C +G V +I
Sbjct: 62 EFPIGTYLNYECRPGYSGR-PFSIICLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKG 120
Query: 428 RTTHGARALYSCRENFTLVGNPERTC---GDEGIWDGEAPRCLFDWCPDPPAVSNA---S 481
G++ YSC + + L+G+ TC GD IWD E P C C PP ++N S
Sbjct: 121 -IQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTITNGDFIS 179
Query: 482 VTVNGHKAGSLASYTCENG------HILSGSTSVTCTLG----GAWSGVPPSCKYVN-CG 530
GS+ +Y C G L G S+ CT G WSG P C N C
Sbjct: 180 TNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCT 239
Query: 531 TPTIHKGSFVLINGTT-TYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCP 589
P + G V N + + + +F C+P + + G + C KW ++PSC P
Sbjct: 240 PPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQP 299
Query: 590 EPEV--PSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCG 647
P+V + ++ + + CE G+ L G ++ C G+WS +PTCE C
Sbjct: 300 PPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCD 359
Query: 648 KLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCT---EEFQWSDSSPRCEEI 704
L LG+ + + C ++L G C E W+ S P CE+I
Sbjct: 360 DFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQI 419
Query: 705 RCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCE------KGYK 758
C P V N R G L + G V Y C+ +
Sbjct: 420 FCPSP--------PVIPNGRHTGKPL----------EVFPFGKTVNYTCDPHPDRGTSFD 461
Query: 759 VIGESLSTC----EDNGQWSGTTPTCQYV-DCGNPGRIENGKVTLPSNATFY--GATAFY 811
+IGES C + NG WS P C + C P K+ +NA+ + G + Y
Sbjct: 462 LIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKY 521
Query: 812 QCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEA 871
+C + C +N WS +CK +C P + +G++ V + + +G
Sbjct: 522 ECRPEY-YGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPV---NGMVHVITDIQVGSRI 577
Query: 872 HYQCERGYNLKGHQTRTCISKG---QWNGTVPVCIPIDCRSPGNIENGKIVISNGSTL-F 927
+Y C G+ L GH + CI G W+ P+C I C P I NG + +N +
Sbjct: 578 NYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHY 637
Query: 928 GSSVEYYC------LSQYQRVGPFLRKCL--DD--GRWSGEEPSC 962
GS V Y C ++ VG C DD G WSG P C
Sbjct: 638 GSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQC 682
Score = 221 bits (541), Expect = 8e-57
Identities = 188/665 (28%), Positives = 271/665 (40%), Gaps = 78/665 (11%)
Query: 352 TCGSPDKLLNTTI-LGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDG---FWSGAPPSCK 407
+C +P +N + + GS+I Y C +G+ L+G S C G W P C
Sbjct: 103 SCRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICD 162
Query: 408 YVNCGGLTPIEDGDVALIDNRTTH-GARALYSC------RENFTLVGNPERTC--GDE-- 456
+ CG I +GD + H G+ Y C R+ F LVG P C D+
Sbjct: 163 RIPCGLPPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQV 222
Query: 457 GIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGSL---ASYTCENGHILSGSTSVTCTL 513
GIW G AP+C+ PP V N + + SL + C+ G ++ G V C
Sbjct: 223 GIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQA 282
Query: 514 GGAWSGVPPSCKYVNCGTP--TIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCN 571
W PSC V C P +H + G ++CEP Y L GA + C
Sbjct: 283 LNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCT 341
Query: 572 RDGKWSYDIPSCELTSCPE--PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQ 629
G WS P+CE+ SC + ++ +G + + + + ++F C+ G +L G C
Sbjct: 342 PQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCV 401
Query: 630 QDGE---WSGDSPTCEYIDCGKLPTLPYG--TMELLNGTTHLGSVIQYSCT------TNY 678
G W+ P CE I C P +P G T + L G + Y+C T++
Sbjct: 402 LAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLE-VFPFGKTVNYTCDPHPDRGTSF 460
Query: 679 RLVGPVRRTCTEEFQ----WSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTS 734
L+G CT + Q WS +PRC + G+ ++ H L
Sbjct: 461 DLIGESTIRCTSDPQGNGVWSSPAPRC----------------GILGHCQAPDHFLFAKL 504
Query: 735 DNRDVGNTYRIGALVKYRCEKGYKVIGESLS-TCEDNGQWSGTTPTCQYVDCGNPGRIEN 793
+ + + IG +KY C Y G S TC DN WS C+ C P N
Sbjct: 505 KTQTNASDFPIGTSLKYECRPEY--YGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVN 562
Query: 794 GKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGT---WSLEPPICKEITCPDPSA 850
G V + ++ G+ Y C L G C +G WS +PPIC+ I C P
Sbjct: 563 GMVHVITDIQV-GSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPT 621
Query: 851 QIKAGSGLLVVTSTLSIGGEAHYQCERG------YNLKGHQTRTCISK----GQWNGTVP 900
I G + G Y+C G + L G + C S G W+G P
Sbjct: 622 -IANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAP 680
Query: 901 VC-IPIDCRSPGNIENGKIVISNGSTLFGSS--VEYYCLSQYQRVGPFLRKCLDDGRWSG 957
C IP C +P N+ENG I++S+ +LF + VE+ C + GP KC +W
Sbjct: 681 QCIIPNKC-TPPNVENG-ILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEP 738
Query: 958 EEPSC 962
E PSC
Sbjct: 739 ELPSC 743
Score = 205 bits (501), Expect = 6e-52
Identities = 178/668 (26%), Positives = 269/668 (40%), Gaps = 72/668 (10%)
Query: 353 CGSPDKLL----NTTILGNDYDVGSRIVYKC-PEGHMLLGDKSRHCKKDGFWSGAPPSCK 407
C +PD L T +D+ +G+ + Y+C PE + S C + WS CK
Sbjct: 943 CQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGR--PFSITCLDNLVWSSPKDVCK 1000
Query: 408 YVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTC---GDEGIWDGEAP 464
+C +G V +I + G+R YSC L+G+ C G+ W + P
Sbjct: 1001 RKSCKTPPDPVNGMVHVITDIQV-GSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPP 1059
Query: 465 RCLFDWCPDPPAVSNAS-VTVNGHKA--GSLASYTCENGHI------LSGSTSVTCTLG- 514
C C PP ++N ++ N GS+ +Y C G L G S+ CT
Sbjct: 1060 ICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSND 1119
Query: 515 ---GAWSGVPPSCKYVN-CGTPTIHKGSFVLINGTT-TYGSIAQFTCEPDYWLNGAEELV 569
G WSG P C N C P + G V N + + + +F C+P + + G +
Sbjct: 1120 DQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVK 1179
Query: 570 CNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAF--DYYVHSTINFHCEAGHKLIGEPNLV 627
C KW ++PSC P PE+ G + + ++ + + CE G+ L G +L
Sbjct: 1180 CQALNKWEPELPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLH 1239
Query: 628 CQQDGEWSGDSPTCEYIDCGK-LPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRR 686
C G+WS ++P C C L LP+G + L LG+ + + C +RL G
Sbjct: 1240 CTPQGDWSPEAPRCAVKSCDDFLGQLPHGRV-LFPLNLQLGAKVSFVCDEGFRLKGSSVS 1298
Query: 687 TCT---EEFQWSDSSPRCEEIRCSDP-IVAEKSIVSVTGNDRSHGHTLIRTSD-NRDVGN 741
C W++S P CE I C +P + D +G + T D + D G
Sbjct: 1299 HCVLVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGM 1358
Query: 742 TYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYV----DCGNPGRIENGKVT 797
T+ + RC S NG WS P C+ C P + T
Sbjct: 1359 TFNLIGESTIRCT----------SDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPT 1408
Query: 798 LPSNATFY--GATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAG 855
+P N + G + Y+C + + C EN WS C+ +C P
Sbjct: 1409 IPINDFEFPVGTSLNYECRPGY-FGKMFSISCLENLVWSSVEDNCRRKSCGPPPEPF--- 1464
Query: 856 SGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQ---WNGTVPVCIPIDCRSPGN 912
+G++ + + G +Y C G+ L G + TC+ G W+ P+C I C P
Sbjct: 1465 NGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPT 1524
Query: 913 IENGKIVISNGSTLF--GSSVEYYCLS------QYQRVGPFLRKCL--DD--GRWSGEEP 960
I NG SN T F G+ V Y C + ++ VG C DD G WS P
Sbjct: 1525 ISNGDF-YSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPP 1583
Query: 961 SCELATNE 968
C ++TN+
Sbjct: 1584 RC-ISTNK 1590
Score = 200 bits (488), Expect = 2e-50
Identities = 170/650 (26%), Positives = 256/650 (39%), Gaps = 79/650 (12%)
Query: 371 VGSRIVYKCPEGHMLLGDKSRHCKKDGF---WSGAPPSCKYVNCGGLTPIEDG-DVALID 426
+G+++ + C EG L G HC G W+ + P C+++ C I +G
Sbjct: 1278 LGAKVSFVCDEGFRLKGSSVSHCVLVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPS 1337
Query: 427 NRTTHGARALYSCREN------FTLVGNPERTCGDE----GIWDGEAPRCLFD----WCP 472
+G Y+C + F L+G C + G+W APRC C
Sbjct: 1338 GDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTSDPHGNGVWSSPAPRCELSVRAGHCK 1397
Query: 473 DPPAVSNASVTV--NGHK--AGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVN 528
P AS T+ N + G+ +Y C G+ S++C WS V +C+ +
Sbjct: 1398 TPEQFPFASPTIPINDFEFPVGTSLNYECRPGYF-GKMFSISCLENLVWSSVEDNCRRKS 1456
Query: 529 CGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGK---WSYDIPSCEL 585
CG P V IN T +GS ++C + L G+ C G W P CE+
Sbjct: 1457 CGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEI 1516
Query: 586 TSC-PEPEVPSGGYM--EAFDYYVHSTINFHCEAG------HKLIGEPNLVC----QQDG 632
SC P P + +G + ++ + + + C G +L+GE ++ C Q G
Sbjct: 1517 ISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVG 1576
Query: 633 EWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTH-LGSVIQYSCTTNYRLVGPVRRTCTEE 691
WS P C + P + N + L +I++ C + +VG C
Sbjct: 1577 VWSSPPPRCISTNKCTAPEVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTN 1636
Query: 692 FQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKY 751
+W P C + C P + HG + DN + G V Y
Sbjct: 1637 GRWGPKLPHCSRV-CQPP------------PEILHGEHTLSHQDN------FSPGQEVFY 1677
Query: 752 RCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGN-PGRIENGKVTLPSNATFYGATAF 810
CE Y + G + C G WS P C C + G++ +G+V LP N GA
Sbjct: 1678 SCEPSYDLRGAASLHCTPQGDWSPEAPRCTVKSCDDFLGQLPHGRVLLPLNLQL-GAKVS 1736
Query: 811 YQCDENWELEGVIRRMCQENG---TWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSI 867
+ CDE + L+G C G W+ P+C++I CP+P A I G +
Sbjct: 1737 FVCDEGFRLKGRSASHCVLAGMKALWNSSVPVCEQIFCPNPPA-ILNGRHTGTPFGDIPY 1795
Query: 868 GGEAHYQC----ERG--YNLKGHQTRTCIS----KGQWNGTVPVC---IPIDCRSPGNIE 914
G E Y C +RG +NL G + C S G W+ P C +P C P I+
Sbjct: 1796 GKEISYACDTHPDRGMTFNLIGESSIRCTSDPQGNGVWSSPAPRCELSVPAACPHPPKIQ 1855
Query: 915 NGKIVISNGST-LFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
NG + + S L G ++ Y C Y VG C D G WS + C+
Sbjct: 1856 NGHYIGGHVSLYLPGMTISYICDPGYLLVGKGFIFCTDQGIWSQLDHYCK 1905
Score = 197 bits (480), Expect = 2e-49
Identities = 174/678 (25%), Positives = 274/678 (40%), Gaps = 90/678 (13%)
Query: 345 ICQYLPPTCGSPDKLLNTTILGND---YDVGSRIVYKCPEGH------MLLGDKSRHCKK 395
IC +P CG P + N + + + GS + Y+C G L+G+ S +C
Sbjct: 160 ICDRIP--CGLPPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTS 217
Query: 396 D----GFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRTTHGARAL--YSCRENFTLVGNP 449
+ G WSG P C N +E+G + + DNR+ + + C+ F + G
Sbjct: 218 NDDQVGIWSGPAPQCIIPNKCTPPNVENG-ILVSDNRSLFSLNEVVEFRCQPGFVMKGPR 276
Query: 450 ERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTV---NGHKAGSLASYTCENGHILSGS 506
C W+ E P C C PP V +A T + G Y+CE G+ L G+
Sbjct: 277 RVKCQALNKWEPELPSCS-RVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGA 335
Query: 507 TSVTCTLGGAWSGVPPSCKYVNCGT--PTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNG 564
S+ CT G WS P+C+ +C + G VL G+ F C+ + L G
Sbjct: 336 ASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGR-VLFPVNLQLGAKVDFVCDEGFQLKG 394
Query: 565 AEELVC---NRDGKWSYDIPSCELTSCPEPEV-PSGGY----MEAFDYYVHSTINFHCE- 615
+ C + W+ +P CE CP P V P+G + +E F + T+N+ C+
Sbjct: 395 SSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPF--GKTVNYTCDP 452
Query: 616 -----AGHKLIGEPNLVCQQD----GEWSGDSPTCEYIDCGKLPT-LPYGTMELLNGTTH 665
LIGE + C D G WS +P C + + P + ++ +
Sbjct: 453 HPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASD 512
Query: 666 --LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGND 723
+G+ ++Y C Y P TC + WS C+ C P D
Sbjct: 513 FPIGTSLKYECRPEY-YGRPFSITCLDNLVWSSPKDVCKRKSCKTP------------PD 559
Query: 724 RSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTC 780
+G + T D+ ++G+ + Y C G+++IG S + C +G WS P C
Sbjct: 560 PVNGMVHVIT----DI----QVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPIC 611
Query: 781 QYVDCGNPGRIENGKVTLPSNATF-YGATAFYQCDEN------WELEGVIRRMCQEN--- 830
Q + CG P I NG + F YG+ Y+C+ +EL G C N
Sbjct: 612 QRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQ 671
Query: 831 -GTWSLEPPICKEITCPDPSAQIKAGSGLLVVT--STLSIGGEAHYQCERGYNLKGHQTR 887
G WS P C P+ +G+LV S S+ ++C+ G+ +KG +
Sbjct: 672 VGIWSGPAPQC---IIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRV 728
Query: 888 TCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLF-GSSVEYYCLSQYQRVGPFL 946
C + +W +P C + C+ P ++ + + + G V Y C Y G
Sbjct: 729 KCQALNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAAS 787
Query: 947 RKCLDDGRWSGEEPSCEL 964
+C G WS P+CE+
Sbjct: 788 MRCTPQGDWSPAAPTCEV 805
Score = 196 bits (479), Expect = 3e-49
Identities = 181/674 (26%), Positives = 263/674 (39%), Gaps = 82/674 (12%)
Query: 353 CGSPDKLLNTTILGNDYDV---GSRIVYKC---PE---GHMLLGDKSRHCKKD----GFW 399
C SP + N G +V G + Y C P+ L+G+ + C D G W
Sbjct: 871 CPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVW 930
Query: 400 SGAPPSCKYV-NCGGLTPIEDGDVALIDNRTTH--GARALYSCRENFTLVGNP-ERTCGD 455
S P C + +C + N + G Y CR + G P TC D
Sbjct: 931 SSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEY--YGRPFSITCLD 988
Query: 456 EGIWDGEAPRCLFDWCPDPPAVSNASV-TVNGHKAGSLASYTCENGHILSGSTSVTCTLG 514
+W C C PP N V + + GS +Y+C GH L G +S C L
Sbjct: 989 NLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILS 1048
Query: 515 GA---WSGVPPSCKYVNCGTP-TIHKGSFVLINGTTT-YGSIAQFTCEPD------YWLN 563
G WS PP C+ + CG P TI G F+ N YGS+ + C + L
Sbjct: 1049 GNTAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELV 1108
Query: 564 GAEELVC--NRD--GKWSYDIPSCELTS-CPEPEVPSGGYMEAFD--YYVHSTINFHCEA 616
G + C N D G WS P C + + C P V +G + + ++ + F C+
Sbjct: 1109 GEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQP 1168
Query: 617 GHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHL-GSVIQYSCT 675
G + G + CQ +W + P+C + C P + +G + G + YSC
Sbjct: 1169 GFVMKGPRRVKCQALNKWEPELPSCSRV-CQPPPEILHGEHTPSHQDNFSPGQEVFYSCE 1227
Query: 676 TNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSD 735
Y L G CT + WS +PRC C D + HG L +
Sbjct: 1228 PGYDLRGAASLHCTPQGDWSPEAPRCAVKSCDDFL-----------GQLPHGRVLFPLN- 1275
Query: 736 NRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTCQYVDCGNPGRIE 792
++GA V + C++G+++ G S+S C G W+ + P C+++ C NP I
Sbjct: 1276 -------LQLGAKVSFVCDEGFRLKGSSVSHCVLVGMRSLWNNSVPVCEHIFCPNPPAIL 1328
Query: 793 NGKVT-LPSNATFYGATAFYQCDEN------WELEGVIRRMCQE----NGTWSLEPPICK 841
NG+ T PS YG Y CD + + L G C NG WS P C+
Sbjct: 1329 NGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTSDPHGNGVWSSPAPRCE 1388
Query: 842 EIT----CPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNG 897
C P A + + +G +Y+C GY K +C+ W+
Sbjct: 1389 LSVRAGHCKTPEQFPFASPTIPINDFEFPVGTSLNYECRPGYFGKMFSI-SCLENLVWSS 1447
Query: 898 TVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGR--- 954
C C P NG + I N T FGS+V Y C ++ +G CL G
Sbjct: 1448 VEDNCRRKSCGPPPEPFNGMVHI-NTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVT 1506
Query: 955 WSGEEPSCELATNE 968
W + P CE+ + E
Sbjct: 1507 WDKKAPICEIISCE 1520
Score = 196 bits (477), Expect = 5e-49
Identities = 186/688 (27%), Positives = 271/688 (39%), Gaps = 83/688 (12%)
Query: 345 ICQYLPPTCGSPDKLLNTTILGN---DYDVGSRIVYKC---PEGHM---LLGDKSRHCKK 395
+C+++ C +P +LN G D G I Y C P+ M L+G+ + C
Sbjct: 1315 VCEHI--FCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTS 1372
Query: 396 D----GFWSGAPPSCKY-VNCGGLT-----PIEDGDVALIDNRTTHGARALYSCRENFTL 445
D G WS P C+ V G P + + D G Y CR +
Sbjct: 1373 DPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDFEFPVGTSLNYECRPGY-- 1430
Query: 446 VGNP-ERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGH-KAGSLASYTCENGHIL 503
G +C + +W C C PP N V +N + GS +Y+C G L
Sbjct: 1431 FGKMFSISCLENLVWSSVEDNCRRKSCGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRL 1490
Query: 504 SGSTSVTCTLGG---AWSGVPPSCKYVNCGTP-TIHKGSFVLINGTTTY-GSIAQFTCE- 557
GS S TC + G W P C+ ++C P TI G F N T+ + G++ + C
Sbjct: 1491 IGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHT 1550
Query: 558 -PD----YWLNGAEELVC-NRD---GKWSYDIPSCELTS-CPEPEVPSGGYMEAFDYYVH 607
PD + L G + C ++D G WS P C T+ C PEV + + +
Sbjct: 1551 GPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRCISTNKCTAPEVENAIRVPGNRSFFT 1610
Query: 608 ST--INFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTH 665
T I F C+ G ++G + CQ +G W P C + C P + +G L +
Sbjct: 1611 LTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHCSRV-CQPPPEILHGEHTLSHQDNF 1669
Query: 666 L-GSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDR 724
G + YSC +Y L G CT + WS +PRC C D +
Sbjct: 1670 SPGQEVFYSCEPSYDLRGAASLHCTPQGDWSPEAPRCTVKSCDDFL-----------GQL 1718
Query: 725 SHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTCQ 781
HG L+ + ++GA V + C++G+++ G S S C G W+ + P C+
Sbjct: 1719 PHGRVLLPLN--------LQLGAKVSFVCDEGFRLKGRSASHCVLAGMKALWNSSVPVCE 1770
Query: 782 YVDCGNPGRIENGKVT-LPSNATFYGATAFYQCDEN------WELEGVIRRMC----QEN 830
+ C NP I NG+ T P YG Y CD + + L G C Q N
Sbjct: 1771 QIFCPNPPAILNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGESSIRCTSDPQGN 1830
Query: 831 GTWSLEPPICK---EITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTR 887
G WS P C+ CP P +I+ G + S G Y C+ GY L G
Sbjct: 1831 GVWSSPAPRCELSVPAACPHPP-KIQNGHYIGGHVSLYLPGMTISYICDPGYLLVGKGFI 1889
Query: 888 TCISKGQWNGTVPVCIPIDCRSPGNIEN-GKIVISNGSTLFGSSVEYYCLSQYQRVGPFL 946
C +G W+ C ++C P + K + +G V C Y G
Sbjct: 1890 FCTDQGIWSQLDHYCKEVNCSFPLFMNGISKELEMKKVYHYGDYVTLKCEDGYTLEGSPW 1949
Query: 947 RKCLDDGRWSGEEPSCELATNEAVDSGT 974
+C D RW C T++A+ GT
Sbjct: 1950 SQCQADDRWDPPLAKCTSRTHDALIVGT 1977
Score = 190 bits (462), Expect = 3e-47
Identities = 174/666 (26%), Positives = 263/666 (39%), Gaps = 79/666 (11%)
Query: 353 CGSPDKLLNTTILGNDYDV---GSRIVYKC---PE---GHMLLGDKSRHCKKD----GFW 399
C SP + N G +V G + Y C P+ L+G+ + C D G W
Sbjct: 421 CPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVW 480
Query: 400 SGAPPSCKYV-NCGGLTPIEDGDVALIDNRTTH--GARALYSCRENFTLVGNP-ERTCGD 455
S P C + +C + N + G Y CR + G P TC D
Sbjct: 481 SSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEY--YGRPFSITCLD 538
Query: 456 EGIWDGEAPRCLFDWCPDPPAVSNASV-TVNGHKAGSLASYTCENGHILSGSTSVTCTLG 514
+W C C PP N V + + GS +Y+C GH L G +S C L
Sbjct: 539 NLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILS 598
Query: 515 GA---WSGVPPSCKYVNCGTP-TIHKGSFVLINGTTT-YGSIAQFTCEPD------YWLN 563
G WS PP C+ + CG P TI G F+ N YGS+ + C P + L
Sbjct: 599 GNAAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELV 658
Query: 564 GAEELVC--NRD--GKWSYDIPSCELTS-CPEPEVPSGGYMEAFD--YYVHSTINFHCEA 616
G + C N D G WS P C + + C P V +G + + ++ + F C+
Sbjct: 659 GEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQP 718
Query: 617 GHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHL-GSVIQYSCT 675
G + G + CQ +W + P+C + C P + + + G + YSC
Sbjct: 719 GFVMKGPRRVKCQALNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCE 777
Query: 676 TNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSD 735
Y L G CT + WS ++P CE C D + +G L +
Sbjct: 778 PGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDFM-----------GQLLNGRVLFPVN- 825
Query: 736 NRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTCQYVDCGNPGRIE 792
++GA V + C++G+++ G S S C G W+ + P C+ + C +P I
Sbjct: 826 -------LQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIP 878
Query: 793 NGKVT-LPSNATFYGATAFYQCD------ENWELEGVIRRMC----QENGTWSLEPPICK 841
NG+ T P +G T Y CD +++L G C Q NG WS P C
Sbjct: 879 NGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCG 938
Query: 842 EI-TCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVP 900
+ C P + A S IG Y+C Y + TC+ W+
Sbjct: 939 ILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGRPFSI-TCLDNLVWSSPKD 997
Query: 901 VCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDG---RWSG 957
VC C++P + NG + + + GS + Y C + ++ +G +C+ G WS
Sbjct: 998 VCKRKSCKTPPDPVNGMVHVITDIQV-GSRINYSCTTGHRLIGHSSAECILSGNTAHWST 1056
Query: 958 EEPSCE 963
+ P C+
Sbjct: 1057 KPPICQ 1062
Score = 169 bits (411), Expect = 5e-41
Identities = 135/509 (26%), Positives = 209/509 (41%), Gaps = 59/509 (11%)
Query: 490 GSLASYTCENGHILSGST-SVTCTLGGAWSGVPPSCKYVNCGTPTIHKGSFVLINGTTTY 548
G+ +Y C G+ SG S+ C W+G C+ +C P V + +
Sbjct: 66 GTYLNYECRPGY--SGRPFSIICLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKGIQF 123
Query: 549 GSIAQFTCEPDYWLNGAEELVCNRDGK---WSYDIPSCELTSCP-EPEVPSGGYMEAF-- 602
GS +++C Y L G+ C G W + P C+ C P + +G ++
Sbjct: 124 GSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTITNGDFISTNRE 183
Query: 603 DYYVHSTINFHCEAGH------KLIGEPNLVC----QQDGEWSGDSPTCEYIDCGKLPTL 652
+++ S + + C G +L+GEP++ C Q G WSG +P C + P +
Sbjct: 184 NFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNV 243
Query: 653 PYGTMELLNGTTH-LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIV 711
G + N + L V+++ C + + GP R C +W P C + C P
Sbjct: 244 ENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRV-CQPP-- 300
Query: 712 AEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNG 771
D H R DN + G V Y CE GY + G + C G
Sbjct: 301 ----------PDVLHAERTQRDKDN------FSPGQEVFYSCEPGYDLRGAASMRCTPQG 344
Query: 772 QWSGTTPTCQYVDCGN-PGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQEN 830
WS PTC+ C + G++ NG+V P N GA + CDE ++L+G C
Sbjct: 345 DWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQL-GAKVDFVCDEGFQLKGSSASYCVLA 403
Query: 831 GT---WSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCE----RG--YNL 881
G W+ P+C++I CP P I G G +Y C+ RG ++L
Sbjct: 404 GMESLWNSSVPVCEQIFCPSPPV-IPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDL 462
Query: 882 KGHQTRTCIS----KGQWNGTVPVC-IPIDCRSPGNIENGKIVISNGSTLF--GSSVEYY 934
G T C S G W+ P C I C++P + K+ ++ F G+S++Y
Sbjct: 463 IGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYE 522
Query: 935 CLSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
C +Y PF CLD+ WS + C+
Sbjct: 523 CRPEYYG-RPFSITCLDNLVWSSPKDVCK 550
Score = 101 bits (243), Expect = 1e-20
Identities = 80/316 (25%), Positives = 124/316 (39%), Gaps = 42/316 (13%)
Query: 666 LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRS 725
+G+ + Y C Y P C + W+ + RC C +P +V V
Sbjct: 65 IGTYLNYECRPGYS-GRPFSIICLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKG--- 120
Query: 726 HGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTCQY 782
+ G+ +KY C KGY++IG S +TC +G W TP C
Sbjct: 121 -----------------IQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDR 163
Query: 783 VDCGNPGRIENGKVTLPSNATF-YGATAFYQCDEN------WELEGVIRRMCQEN----G 831
+ CG P I NG + F YG+ Y+C+ +EL G C N G
Sbjct: 164 IPCGLPPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVG 223
Query: 832 TWSLEPPICKEITCPDPSAQIKAGSGLLVV--TSTLSIGGEAHYQCERGYNLKGHQTRTC 889
WS P C P+ +G+LV S S+ ++C+ G+ +KG + C
Sbjct: 224 IWSGPAPQC---IIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKC 280
Query: 890 ISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLF-GSSVEYYCLSQYQRVGPFLRK 948
+ +W +P C + C+ P ++ + + + G V Y C Y G +
Sbjct: 281 QALNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMR 339
Query: 949 CLDDGRWSGEEPSCEL 964
C G WS P+CE+
Sbjct: 340 CTPQGDWSPAAPTCEV 355
Score = 44.0 bits (99), Expect = 0.003
Identities = 17/42 (40%), Positives = 24/42 (57%)
Query: 17 NEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
+++N G Y C+ GY+L GA CT +GDW+ E P C
Sbjct: 1212 HQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGDWSPEAPRC 1253
Score = 42.7 bits (96), Expect = 0.007
Identities = 18/57 (31%), Positives = 28/57 (49%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C P + ++ +++N G Y C+ Y+L GA CT +GDW+ E P C
Sbjct: 1650 CQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCTPQGDWSPEAPRC 1706
Score = 42.3 bits (95), Expect = 0.009
Identities = 19/57 (33%), Positives = 28/57 (49%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C P +A + +++N G Y C+ GY+L GA CT +GDW+ P C
Sbjct: 297 CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTC 353
Score = 42.3 bits (95), Expect = 0.009
Identities = 19/57 (33%), Positives = 28/57 (49%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C P +A + +++N G Y C+ GY+L GA CT +GDW+ P C
Sbjct: 747 CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTC 803
Score = 37.5 bits (83), Expect = 0.26
Identities = 20/60 (33%), Positives = 27/60 (45%), Gaps = 5/60 (8%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGD---WTLEPPFC 58
C +P P N V + + I G+ Y C +GY L G+ C + GD W E P C
Sbjct: 104 CRNPPDPVNGMVHVI--KGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPIC 161
Score = 37.5 bits (83), Expect = 0.26
Identities = 20/60 (33%), Positives = 27/60 (45%), Gaps = 5/60 (8%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGD---WTLEPPFC 58
C P P N V + + I G+ Y C G+ L G EC L G+ W+ +PP C
Sbjct: 554 CKTPPDPVNGMVHVITD--IQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPIC 611
Score = 37.5 bits (83), Expect = 0.26
Identities = 20/60 (33%), Positives = 27/60 (45%), Gaps = 5/60 (8%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGD---WTLEPPFC 58
C P P N V + + I G+ Y C G+ L G EC L G+ W+ +PP C
Sbjct: 1004 CKTPPDPVNGMVHVITD--IQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPIC 1061
Score = 37.5 bits (83), Expect = 0.26
Identities = 19/60 (31%), Positives = 27/60 (45%), Gaps = 5/60 (8%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGD---WTLEPPFC 58
CG P P N V I + G+ Y C+EG+ L G+ C + G+ W + P C
Sbjct: 1457 CGPPPEPFNGMVHINTDTQF--GSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPIC 1514
>AL137789-3|CAI16042.1| 2039|Homo sapiens complement component (3b/4b)
receptor 1 (Knops blood group) protein.
Length = 2039
Score = 234 bits (573), Expect = 1e-60
Identities = 194/665 (29%), Positives = 275/665 (41%), Gaps = 78/665 (11%)
Query: 352 TCGSPDKLLNTTI-LGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDG---FWSGAPPSCK 407
+C +P +N + + D VGSRI Y C GH L+G S C G WS PP C+
Sbjct: 553 SCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQ 612
Query: 408 YVNCGGLTPIEDGDVALIDNRTTH-GARALYSC------RENFTLVGNPERTC--GDE-- 456
+ CG I +GD + H G+ Y C R+ F LVG P C D+
Sbjct: 613 RIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQV 672
Query: 457 GIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGSL---ASYTCENGHILSGSTSVTCTL 513
GIW G AP+C+ PP V N + + SL + C+ G ++ G V C
Sbjct: 673 GIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQA 732
Query: 514 GGAWSGVPPSCKYVNCGTP--TIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCN 571
W PSC V C P +H + G ++CEP Y L GA + C
Sbjct: 733 LNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCT 791
Query: 572 RDGKWSYDIPSCELTSCPE--PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQ 629
G WS P+CE+ SC + ++ +G + + + + ++F C+ G +L G C
Sbjct: 792 PQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCV 851
Query: 630 QDGE---WSGDSPTCEYIDCGKLPTLPYG--TMELLNGTTHLGSVIQYSCT------TNY 678
G W+ P CE I C P +P G T + L G + Y+C T++
Sbjct: 852 LAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLE-VFPFGKAVNYTCDPHPDRGTSF 910
Query: 679 RLVGPVRRTCTEEFQ----WSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTS 734
L+G CT + Q WS +PRC + G+ ++ H L
Sbjct: 911 DLIGESTIRCTSDPQGNGVWSSPAPRC----------------GILGHCQAPDHFLFAKL 954
Query: 735 DNRDVGNTYRIGALVKYRCEKGYKVIGESLS-TCEDNGQWSGTTPTCQYVDCGNPGRIEN 793
+ + + IG +KY C Y G S TC DN WS C+ C P N
Sbjct: 955 KTQTNASDFPIGTSLKYECRPEY--YGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVN 1012
Query: 794 GKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGT---WSLEPPICKEITCPDPSA 850
G V + ++ G+ Y C L G C +G WS +PPIC+ I C P
Sbjct: 1013 GMVHVITDIQV-GSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPCGLPPT 1071
Query: 851 QIKAGSGLLVVTSTLSIGGEAHYQCERG------YNLKGHQTRTCISK----GQWNGTVP 900
I G + G Y+C G + L G + C S G W+G P
Sbjct: 1072 -IANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAP 1130
Query: 901 VC-IPIDCRSPGNIENGKIVISNGSTLFGSS--VEYYCLSQYQRVGPFLRKCLDDGRWSG 957
C IP C +P N+ENG I++S+ +LF + VE+ C + GP KC +W
Sbjct: 1131 QCIIPNKC-TPPNVENG-ILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEP 1188
Query: 958 EEPSC 962
E PSC
Sbjct: 1189 ELPSC 1193
Score = 227 bits (555), Expect = 2e-58
Identities = 187/662 (28%), Positives = 274/662 (41%), Gaps = 69/662 (10%)
Query: 352 TCGSPDKLLNTTI-LGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDG---FWSGAPPSCK 407
+C +P +N + + D VGSRI Y C GH L+G S C G WS PP C+
Sbjct: 1003 SCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQ 1062
Query: 408 YVNCGGLTPIEDGDVALIDNRTTH-GARALYSC------RENFTLVGNPERTC--GDE-- 456
+ CG I +GD + H G+ Y C R+ F LVG P C D+
Sbjct: 1063 RIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQV 1122
Query: 457 GIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGSL---ASYTCENGHILSGSTSVTCTL 513
GIW G AP+C+ PP V N + + SL + C+ G ++ G V C
Sbjct: 1123 GIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQA 1182
Query: 514 GGAWSGVPPSCKYVNCGTPTIHKGSFVLINGTT-TYGSIAQFTCEPDYWLNGAEELVCNR 572
W PSC V P I G + + G ++CEP Y L GA L C
Sbjct: 1183 LNKWEPELPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTP 1242
Query: 573 DGKWSYDIPSCELTSCPE--PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQ 630
G WS + P C + SC + ++P G + + + + ++F C+ G +L G C
Sbjct: 1243 QGDWSPEAPRCAVKSCDDFLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCVL 1302
Query: 631 DGE---WSGDSPTCEYIDCGKLPTLPYGT-MELLNGTTHLGSVIQYSCTTN------YRL 680
G W+ P CE+I C P + G +G G I Y+C + + L
Sbjct: 1303 VGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNL 1362
Query: 681 VGPVRRTCTEEFQ----WSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDN 736
+G CT + WS +PRCE ++ ++ T I +D
Sbjct: 1363 IGESTIRCTSDPHGNGVWSSPAPRCE--------LSVRAGHCKTPEQFPFASPTIPINDF 1414
Query: 737 RDVGNTYRIGALVKYRCEKGYKVIGESLS-TCEDNGQWSGTTPTCQYVDCGNPGRIENGK 795
+ +G + Y C GY G+ S +C +N WS C+ CG P NG
Sbjct: 1415 E-----FPVGTSLNYECRPGY--FGKMFSISCLENLVWSSVEDNCRRKSCGPPPEPFNGM 1467
Query: 796 VTLPSNATFYGATAFYQCDENWELEGVIRRMCQENG---TWSLEPPICKEITCPDPSAQI 852
V + ++ T +G+T Y C+E + L G C +G TW + PIC+ I+C +P I
Sbjct: 1468 VHINTD-TQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISC-EPPPTI 1525
Query: 853 KAGSGLLVVTSTLSIGGEAHYQCERG------YNLKGHQTRTCISK----GQWNGTVPVC 902
G ++ G YQC G + L G ++ C SK G W+ P C
Sbjct: 1526 SNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRC 1585
Query: 903 IPID-CRSPGNIENGKIVISNGSTL-FGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEP 960
I + C +P +EN V N S + + C + VG +C +GRW + P
Sbjct: 1586 ISTNKCTAP-EVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLP 1644
Query: 961 SC 962
C
Sbjct: 1645 HC 1646
Score = 224 bits (547), Expect = 2e-57
Identities = 175/645 (27%), Positives = 261/645 (40%), Gaps = 74/645 (11%)
Query: 368 DYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDN 427
++ +G+ + Y+C G+ S C K+ W+GA C+ +C +G V +I
Sbjct: 62 EFPIGTYLNYECRPGYSGR-PFSIICLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKG 120
Query: 428 RTTHGARALYSCRENFTLVGNPERTC---GDEGIWDGEAPRCLFDWCPDPPAVSNA---S 481
G++ YSC + + L+G+ TC GD IWD E P C C PP ++N S
Sbjct: 121 -IQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTIANGDFIS 179
Query: 482 VTVNGHKAGSLASYTCENG------HILSGSTSVTCTLG----GAWSGVPPSCKYVN-CG 530
GS+ +Y C G L G S+ CT G WSG P C N C
Sbjct: 180 TNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCT 239
Query: 531 TPTIHKGSFVLINGTT-TYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCP 589
P + G V N + + + +F C+P + + G + C KW ++PSC P
Sbjct: 240 PPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQP 299
Query: 590 EPEV--PSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCG 647
P+V + ++ + + CE G+ L G ++ C G+WS +PTCE C
Sbjct: 300 PPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCD 359
Query: 648 KLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCT---EEFQWSDSSPRCEEI 704
L LG+ + + C ++L G C E W+ S P CE+I
Sbjct: 360 DFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQI 419
Query: 705 RCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCE------KGYK 758
C P V N R G L + G V Y C+ +
Sbjct: 420 FCPSP--------PVIPNGRHTGKPL----------EVFPFGKTVNYTCDPHPDRGTSFD 461
Query: 759 VIGESLSTC----EDNGQWSGTTPTCQYV-DCGNPGRIENGKVTLPSNATFY--GATAFY 811
+IGES C + NG WS P C + C P K+ +NA+ + G + Y
Sbjct: 462 LIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKY 521
Query: 812 QCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEA 871
+C + C +N WS +CK +C P + +G++ V + + +G
Sbjct: 522 ECRPEY-YGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPV---NGMVHVITDIQVGSRI 577
Query: 872 HYQCERGYNLKGHQTRTCISKG---QWNGTVPVCIPIDCRSPGNIENGKIVISNGSTL-F 927
+Y C G+ L GH + CI G W+ P+C I C P I NG + +N +
Sbjct: 578 NYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHY 637
Query: 928 GSSVEYYC------LSQYQRVGPFLRKCL--DD--GRWSGEEPSC 962
GS V Y C ++ VG C DD G WSG P C
Sbjct: 638 GSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQC 682
Score = 221 bits (541), Expect = 8e-57
Identities = 188/665 (28%), Positives = 271/665 (40%), Gaps = 78/665 (11%)
Query: 352 TCGSPDKLLNTTI-LGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDG---FWSGAPPSCK 407
+C +P +N + + GS+I Y C +G+ L+G S C G W P C
Sbjct: 103 SCRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICD 162
Query: 408 YVNCGGLTPIEDGDVALIDNRTTH-GARALYSC------RENFTLVGNPERTC--GDE-- 456
+ CG I +GD + H G+ Y C R+ F LVG P C D+
Sbjct: 163 RIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQV 222
Query: 457 GIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGSL---ASYTCENGHILSGSTSVTCTL 513
GIW G AP+C+ PP V N + + SL + C+ G ++ G V C
Sbjct: 223 GIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQA 282
Query: 514 GGAWSGVPPSCKYVNCGTP--TIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCN 571
W PSC V C P +H + G ++CEP Y L GA + C
Sbjct: 283 LNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCT 341
Query: 572 RDGKWSYDIPSCELTSCPE--PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQ 629
G WS P+CE+ SC + ++ +G + + + + ++F C+ G +L G C
Sbjct: 342 PQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCV 401
Query: 630 QDGE---WSGDSPTCEYIDCGKLPTLPYG--TMELLNGTTHLGSVIQYSCT------TNY 678
G W+ P CE I C P +P G T + L G + Y+C T++
Sbjct: 402 LAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLE-VFPFGKTVNYTCDPHPDRGTSF 460
Query: 679 RLVGPVRRTCTEEFQ----WSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTS 734
L+G CT + Q WS +PRC + G+ ++ H L
Sbjct: 461 DLIGESTIRCTSDPQGNGVWSSPAPRC----------------GILGHCQAPDHFLFAKL 504
Query: 735 DNRDVGNTYRIGALVKYRCEKGYKVIGESLS-TCEDNGQWSGTTPTCQYVDCGNPGRIEN 793
+ + + IG +KY C Y G S TC DN WS C+ C P N
Sbjct: 505 KTQTNASDFPIGTSLKYECRPEY--YGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVN 562
Query: 794 GKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGT---WSLEPPICKEITCPDPSA 850
G V + ++ G+ Y C L G C +G WS +PPIC+ I C P
Sbjct: 563 GMVHVITDIQV-GSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPT 621
Query: 851 QIKAGSGLLVVTSTLSIGGEAHYQCERG------YNLKGHQTRTCISK----GQWNGTVP 900
I G + G Y+C G + L G + C S G W+G P
Sbjct: 622 -IANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAP 680
Query: 901 VC-IPIDCRSPGNIENGKIVISNGSTLFGSS--VEYYCLSQYQRVGPFLRKCLDDGRWSG 957
C IP C +P N+ENG I++S+ +LF + VE+ C + GP KC +W
Sbjct: 681 QCIIPNKC-TPPNVENG-ILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEP 738
Query: 958 EEPSC 962
E PSC
Sbjct: 739 ELPSC 743
Score = 205 bits (501), Expect = 6e-52
Identities = 178/668 (26%), Positives = 269/668 (40%), Gaps = 72/668 (10%)
Query: 353 CGSPDKLL----NTTILGNDYDVGSRIVYKC-PEGHMLLGDKSRHCKKDGFWSGAPPSCK 407
C +PD L T +D+ +G+ + Y+C PE + S C + WS CK
Sbjct: 943 CQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGR--PFSITCLDNLVWSSPKDVCK 1000
Query: 408 YVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTC---GDEGIWDGEAP 464
+C +G V +I + G+R YSC L+G+ C G+ W + P
Sbjct: 1001 RKSCKTPPDPVNGMVHVITDIQV-GSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPP 1059
Query: 465 RCLFDWCPDPPAVSNAS-VTVNGHKA--GSLASYTCENGHI------LSGSTSVTCTLG- 514
C C PP ++N ++ N GS+ +Y C G L G S+ CT
Sbjct: 1060 ICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSND 1119
Query: 515 ---GAWSGVPPSCKYVN-CGTPTIHKGSFVLINGTT-TYGSIAQFTCEPDYWLNGAEELV 569
G WSG P C N C P + G V N + + + +F C+P + + G +
Sbjct: 1120 DQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVK 1179
Query: 570 CNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAF--DYYVHSTINFHCEAGHKLIGEPNLV 627
C KW ++PSC P PE+ G + + ++ + + CE G+ L G +L
Sbjct: 1180 CQALNKWEPELPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLH 1239
Query: 628 CQQDGEWSGDSPTCEYIDCGK-LPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRR 686
C G+WS ++P C C L LP+G + L LG+ + + C +RL G
Sbjct: 1240 CTPQGDWSPEAPRCAVKSCDDFLGQLPHGRV-LFPLNLQLGAKVSFVCDEGFRLKGSSVS 1298
Query: 687 TCT---EEFQWSDSSPRCEEIRCSDP-IVAEKSIVSVTGNDRSHGHTLIRTSD-NRDVGN 741
C W++S P CE I C +P + D +G + T D + D G
Sbjct: 1299 HCVLVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGM 1358
Query: 742 TYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYV----DCGNPGRIENGKVT 797
T+ + RC S NG WS P C+ C P + T
Sbjct: 1359 TFNLIGESTIRCT----------SDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPT 1408
Query: 798 LPSNATFY--GATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAG 855
+P N + G + Y+C + + C EN WS C+ +C P
Sbjct: 1409 IPINDFEFPVGTSLNYECRPGY-FGKMFSISCLENLVWSSVEDNCRRKSCGPPPEPF--- 1464
Query: 856 SGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQ---WNGTVPVCIPIDCRSPGN 912
+G++ + + G +Y C G+ L G + TC+ G W+ P+C I C P
Sbjct: 1465 NGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPT 1524
Query: 913 IENGKIVISNGSTLF--GSSVEYYCLS------QYQRVGPFLRKCL--DD--GRWSGEEP 960
I NG SN T F G+ V Y C + ++ VG C DD G WS P
Sbjct: 1525 ISNGDF-YSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPP 1583
Query: 961 SCELATNE 968
C ++TN+
Sbjct: 1584 RC-ISTNK 1590
Score = 200 bits (488), Expect = 2e-50
Identities = 170/650 (26%), Positives = 256/650 (39%), Gaps = 79/650 (12%)
Query: 371 VGSRIVYKCPEGHMLLGDKSRHCKKDGF---WSGAPPSCKYVNCGGLTPIEDG-DVALID 426
+G+++ + C EG L G HC G W+ + P C+++ C I +G
Sbjct: 1278 LGAKVSFVCDEGFRLKGSSVSHCVLVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPS 1337
Query: 427 NRTTHGARALYSCREN------FTLVGNPERTCGDE----GIWDGEAPRCLFD----WCP 472
+G Y+C + F L+G C + G+W APRC C
Sbjct: 1338 GDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTSDPHGNGVWSSPAPRCELSVRAGHCK 1397
Query: 473 DPPAVSNASVTV--NGHK--AGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVN 528
P AS T+ N + G+ +Y C G+ S++C WS V +C+ +
Sbjct: 1398 TPEQFPFASPTIPINDFEFPVGTSLNYECRPGYF-GKMFSISCLENLVWSSVEDNCRRKS 1456
Query: 529 CGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGK---WSYDIPSCEL 585
CG P V IN T +GS ++C + L G+ C G W P CE+
Sbjct: 1457 CGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEI 1516
Query: 586 TSC-PEPEVPSGGYM--EAFDYYVHSTINFHCEAG------HKLIGEPNLVC----QQDG 632
SC P P + +G + ++ + + + C G +L+GE ++ C Q G
Sbjct: 1517 ISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVG 1576
Query: 633 EWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTH-LGSVIQYSCTTNYRLVGPVRRTCTEE 691
WS P C + P + N + L +I++ C + +VG C
Sbjct: 1577 VWSSPPPRCISTNKCTAPEVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTN 1636
Query: 692 FQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKY 751
+W P C + C P + HG + DN + G V Y
Sbjct: 1637 GRWGPKLPHCSRV-CQPP------------PEILHGEHTLSHQDN------FSPGQEVFY 1677
Query: 752 RCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGN-PGRIENGKVTLPSNATFYGATAF 810
CE Y + G + C G WS P C C + G++ +G+V LP N GA
Sbjct: 1678 SCEPSYDLRGAASLHCTPQGDWSPEAPRCTVKSCDDFLGQLPHGRVLLPLNLQL-GAKVS 1736
Query: 811 YQCDENWELEGVIRRMCQENG---TWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSI 867
+ CDE + L+G C G W+ P+C++I CP+P A I G +
Sbjct: 1737 FVCDEGFRLKGRSASHCVLAGMKALWNSSVPVCEQIFCPNPPA-ILNGRHTGTPFGDIPY 1795
Query: 868 GGEAHYQC----ERG--YNLKGHQTRTCIS----KGQWNGTVPVC---IPIDCRSPGNIE 914
G E Y C +RG +NL G + C S G W+ P C +P C P I+
Sbjct: 1796 GKEISYACDTHPDRGMTFNLIGESSIRCTSDPQGNGVWSSPAPRCELSVPAACPHPPKIQ 1855
Query: 915 NGKIVISNGST-LFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
NG + + S L G ++ Y C Y VG C D G WS + C+
Sbjct: 1856 NGHYIGGHVSLYLPGMTISYICDPGYLLVGKGFIFCTDQGIWSQLDHYCK 1905
Score = 197 bits (480), Expect = 2e-49
Identities = 174/678 (25%), Positives = 274/678 (40%), Gaps = 90/678 (13%)
Query: 345 ICQYLPPTCGSPDKLLNTTILGND---YDVGSRIVYKCPEGH------MLLGDKSRHCKK 395
IC +P CG P + N + + + GS + Y+C G L+G+ S +C
Sbjct: 160 ICDRIP--CGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTS 217
Query: 396 D----GFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRTTHGARAL--YSCRENFTLVGNP 449
+ G WSG P C N +E+G + + DNR+ + + C+ F + G
Sbjct: 218 NDDQVGIWSGPAPQCIIPNKCTPPNVENG-ILVSDNRSLFSLNEVVEFRCQPGFVMKGPR 276
Query: 450 ERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTV---NGHKAGSLASYTCENGHILSGS 506
C W+ E P C C PP V +A T + G Y+CE G+ L G+
Sbjct: 277 RVKCQALNKWEPELPSCS-RVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGA 335
Query: 507 TSVTCTLGGAWSGVPPSCKYVNCGT--PTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNG 564
S+ CT G WS P+C+ +C + G VL G+ F C+ + L G
Sbjct: 336 ASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGR-VLFPVNLQLGAKVDFVCDEGFQLKG 394
Query: 565 AEELVC---NRDGKWSYDIPSCELTSCPEPEV-PSGGY----MEAFDYYVHSTINFHCE- 615
+ C + W+ +P CE CP P V P+G + +E F + T+N+ C+
Sbjct: 395 SSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPF--GKTVNYTCDP 452
Query: 616 -----AGHKLIGEPNLVCQQD----GEWSGDSPTCEYIDCGKLPT-LPYGTMELLNGTTH 665
LIGE + C D G WS +P C + + P + ++ +
Sbjct: 453 HPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASD 512
Query: 666 --LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGND 723
+G+ ++Y C Y P TC + WS C+ C P D
Sbjct: 513 FPIGTSLKYECRPEY-YGRPFSITCLDNLVWSSPKDVCKRKSCKTP------------PD 559
Query: 724 RSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTC 780
+G + T D+ ++G+ + Y C G+++IG S + C +G WS P C
Sbjct: 560 PVNGMVHVIT----DI----QVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPIC 611
Query: 781 QYVDCGNPGRIENGKVTLPSNATF-YGATAFYQCDEN------WELEGVIRRMCQEN--- 830
Q + CG P I NG + F YG+ Y+C+ +EL G C N
Sbjct: 612 QRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQ 671
Query: 831 -GTWSLEPPICKEITCPDPSAQIKAGSGLLVVT--STLSIGGEAHYQCERGYNLKGHQTR 887
G WS P C P+ +G+LV S S+ ++C+ G+ +KG +
Sbjct: 672 VGIWSGPAPQC---IIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRV 728
Query: 888 TCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLF-GSSVEYYCLSQYQRVGPFL 946
C + +W +P C + C+ P ++ + + + G V Y C Y G
Sbjct: 729 KCQALNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAAS 787
Query: 947 RKCLDDGRWSGEEPSCEL 964
+C G WS P+CE+
Sbjct: 788 MRCTPQGDWSPAAPTCEV 805
Score = 196 bits (479), Expect = 3e-49
Identities = 181/674 (26%), Positives = 263/674 (39%), Gaps = 82/674 (12%)
Query: 353 CGSPDKLLNTTILGNDYDV---GSRIVYKC---PE---GHMLLGDKSRHCKKD----GFW 399
C SP + N G +V G + Y C P+ L+G+ + C D G W
Sbjct: 871 CPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVW 930
Query: 400 SGAPPSCKYV-NCGGLTPIEDGDVALIDNRTTH--GARALYSCRENFTLVGNP-ERTCGD 455
S P C + +C + N + G Y CR + G P TC D
Sbjct: 931 SSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEY--YGRPFSITCLD 988
Query: 456 EGIWDGEAPRCLFDWCPDPPAVSNASV-TVNGHKAGSLASYTCENGHILSGSTSVTCTLG 514
+W C C PP N V + + GS +Y+C GH L G +S C L
Sbjct: 989 NLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILS 1048
Query: 515 GA---WSGVPPSCKYVNCGTP-TIHKGSFVLINGTTT-YGSIAQFTCEPD------YWLN 563
G WS PP C+ + CG P TI G F+ N YGS+ + C + L
Sbjct: 1049 GNTAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELV 1108
Query: 564 GAEELVC--NRD--GKWSYDIPSCELTS-CPEPEVPSGGYMEAFD--YYVHSTINFHCEA 616
G + C N D G WS P C + + C P V +G + + ++ + F C+
Sbjct: 1109 GEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQP 1168
Query: 617 GHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHL-GSVIQYSCT 675
G + G + CQ +W + P+C + C P + +G + G + YSC
Sbjct: 1169 GFVMKGPRRVKCQALNKWEPELPSCSRV-CQPPPEILHGEHTPSHQDNFSPGQEVFYSCE 1227
Query: 676 TNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSD 735
Y L G CT + WS +PRC C D + HG L +
Sbjct: 1228 PGYDLRGAASLHCTPQGDWSPEAPRCAVKSCDDFL-----------GQLPHGRVLFPLN- 1275
Query: 736 NRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTCQYVDCGNPGRIE 792
++GA V + C++G+++ G S+S C G W+ + P C+++ C NP I
Sbjct: 1276 -------LQLGAKVSFVCDEGFRLKGSSVSHCVLVGMRSLWNNSVPVCEHIFCPNPPAIL 1328
Query: 793 NGKVT-LPSNATFYGATAFYQCDEN------WELEGVIRRMCQE----NGTWSLEPPICK 841
NG+ T PS YG Y CD + + L G C NG WS P C+
Sbjct: 1329 NGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTSDPHGNGVWSSPAPRCE 1388
Query: 842 EIT----CPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNG 897
C P A + + +G +Y+C GY K +C+ W+
Sbjct: 1389 LSVRAGHCKTPEQFPFASPTIPINDFEFPVGTSLNYECRPGYFGKMFSI-SCLENLVWSS 1447
Query: 898 TVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGR--- 954
C C P NG + I N T FGS+V Y C ++ +G CL G
Sbjct: 1448 VEDNCRRKSCGPPPEPFNGMVHI-NTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVT 1506
Query: 955 WSGEEPSCELATNE 968
W + P CE+ + E
Sbjct: 1507 WDKKAPICEIISCE 1520
Score = 196 bits (477), Expect = 5e-49
Identities = 186/688 (27%), Positives = 271/688 (39%), Gaps = 83/688 (12%)
Query: 345 ICQYLPPTCGSPDKLLNTTILGN---DYDVGSRIVYKC---PEGHM---LLGDKSRHCKK 395
+C+++ C +P +LN G D G I Y C P+ M L+G+ + C
Sbjct: 1315 VCEHI--FCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTS 1372
Query: 396 D----GFWSGAPPSCKY-VNCGGLT-----PIEDGDVALIDNRTTHGARALYSCRENFTL 445
D G WS P C+ V G P + + D G Y CR +
Sbjct: 1373 DPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDFEFPVGTSLNYECRPGY-- 1430
Query: 446 VGNP-ERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGH-KAGSLASYTCENGHIL 503
G +C + +W C C PP N V +N + GS +Y+C G L
Sbjct: 1431 FGKMFSISCLENLVWSSVEDNCRRKSCGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRL 1490
Query: 504 SGSTSVTCTLGG---AWSGVPPSCKYVNCGTP-TIHKGSFVLINGTTTY-GSIAQFTCE- 557
GS S TC + G W P C+ ++C P TI G F N T+ + G++ + C
Sbjct: 1491 IGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHT 1550
Query: 558 -PD----YWLNGAEELVC-NRD---GKWSYDIPSCELTS-CPEPEVPSGGYMEAFDYYVH 607
PD + L G + C ++D G WS P C T+ C PEV + + +
Sbjct: 1551 GPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRCISTNKCTAPEVENAIRVPGNRSFFT 1610
Query: 608 ST--INFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTH 665
T I F C+ G ++G + CQ +G W P C + C P + +G L +
Sbjct: 1611 LTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHCSRV-CQPPPEILHGEHTLSHQDNF 1669
Query: 666 L-GSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDR 724
G + YSC +Y L G CT + WS +PRC C D +
Sbjct: 1670 SPGQEVFYSCEPSYDLRGAASLHCTPQGDWSPEAPRCTVKSCDDFL-----------GQL 1718
Query: 725 SHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTCQ 781
HG L+ + ++GA V + C++G+++ G S S C G W+ + P C+
Sbjct: 1719 PHGRVLLPLN--------LQLGAKVSFVCDEGFRLKGRSASHCVLAGMKALWNSSVPVCE 1770
Query: 782 YVDCGNPGRIENGKVT-LPSNATFYGATAFYQCDEN------WELEGVIRRMC----QEN 830
+ C NP I NG+ T P YG Y CD + + L G C Q N
Sbjct: 1771 QIFCPNPPAILNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGESSIRCTSDPQGN 1830
Query: 831 GTWSLEPPICK---EITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTR 887
G WS P C+ CP P +I+ G + S G Y C+ GY L G
Sbjct: 1831 GVWSSPAPRCELSVPAACPHPP-KIQNGHYIGGHVSLYLPGMTISYICDPGYLLVGKGFI 1889
Query: 888 TCISKGQWNGTVPVCIPIDCRSPGNIEN-GKIVISNGSTLFGSSVEYYCLSQYQRVGPFL 946
C +G W+ C ++C P + K + +G V C Y G
Sbjct: 1890 FCTDQGIWSQLDHYCKEVNCSFPLFMNGISKELEMKKVYHYGDYVTLKCEDGYTLEGSPW 1949
Query: 947 RKCLDDGRWSGEEPSCELATNEAVDSGT 974
+C D RW C T++A+ GT
Sbjct: 1950 SQCQADDRWDPPLAKCTSRTHDALIVGT 1977
Score = 188 bits (457), Expect = 1e-46
Identities = 173/666 (25%), Positives = 262/666 (39%), Gaps = 79/666 (11%)
Query: 353 CGSPDKLLNTTILGNDYDV---GSRIVYKC---PE---GHMLLGDKSRHCKKD----GFW 399
C SP + N G +V G + Y C P+ L+G+ + C D G W
Sbjct: 421 CPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVW 480
Query: 400 SGAPPSCKYV-NCGGLTPIEDGDVALIDNRTTH--GARALYSCRENFTLVGNP-ERTCGD 455
S P C + +C + N + G Y CR + G P TC D
Sbjct: 481 SSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEY--YGRPFSITCLD 538
Query: 456 EGIWDGEAPRCLFDWCPDPPAVSNASV-TVNGHKAGSLASYTCENGHILSGSTSVTCTLG 514
+W C C PP N V + + GS +Y+C GH L G +S C L
Sbjct: 539 NLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILS 598
Query: 515 GA---WSGVPPSCKYVNCGTP-TIHKGSFVLINGTTT-YGSIAQFTCEPD------YWLN 563
G WS PP C+ + CG P TI G F+ N YGS+ + C P + L
Sbjct: 599 GNAAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELV 658
Query: 564 GAEELVC--NRD--GKWSYDIPSCELTS-CPEPEVPSGGYMEAFD--YYVHSTINFHCEA 616
G + C N D G WS P C + + C P V +G + + ++ + F C+
Sbjct: 659 GEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQP 718
Query: 617 GHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHL-GSVIQYSCT 675
G + G + CQ +W + P+C + C P + + + G + YSC
Sbjct: 719 GFVMKGPRRVKCQALNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCE 777
Query: 676 TNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSD 735
Y L G CT + WS ++P CE C D + +G L +
Sbjct: 778 PGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDFM-----------GQLLNGRVLFPVN- 825
Query: 736 NRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTCQYVDCGNPGRIE 792
++GA V + C++G+++ G S S C G W+ + P C+ + C +P I
Sbjct: 826 -------LQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIP 878
Query: 793 NGKVT-LPSNATFYGATAFYQCD------ENWELEGVIRRMC----QENGTWSLEPPICK 841
NG+ T P +G Y CD +++L G C Q NG WS P C
Sbjct: 879 NGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCG 938
Query: 842 EI-TCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVP 900
+ C P + A S IG Y+C Y + TC+ W+
Sbjct: 939 ILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGRPFSI-TCLDNLVWSSPKD 997
Query: 901 VCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDG---RWSG 957
VC C++P + NG + + + GS + Y C + ++ +G +C+ G WS
Sbjct: 998 VCKRKSCKTPPDPVNGMVHVITDIQV-GSRINYSCTTGHRLIGHSSAECILSGNTAHWST 1056
Query: 958 EEPSCE 963
+ P C+
Sbjct: 1057 KPPICQ 1062
Score = 169 bits (411), Expect = 5e-41
Identities = 135/509 (26%), Positives = 209/509 (41%), Gaps = 59/509 (11%)
Query: 490 GSLASYTCENGHILSGST-SVTCTLGGAWSGVPPSCKYVNCGTPTIHKGSFVLINGTTTY 548
G+ +Y C G+ SG S+ C W+G C+ +C P V + +
Sbjct: 66 GTYLNYECRPGY--SGRPFSIICLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKGIQF 123
Query: 549 GSIAQFTCEPDYWLNGAEELVCNRDGK---WSYDIPSCELTSCP-EPEVPSGGYMEAF-- 602
GS +++C Y L G+ C G W + P C+ C P + +G ++
Sbjct: 124 GSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTIANGDFISTNRE 183
Query: 603 DYYVHSTINFHCEAGH------KLIGEPNLVC----QQDGEWSGDSPTCEYIDCGKLPTL 652
+++ S + + C G +L+GEP++ C Q G WSG +P C + P +
Sbjct: 184 NFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNV 243
Query: 653 PYGTMELLNGTTH-LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIV 711
G + N + L V+++ C + + GP R C +W P C + C P
Sbjct: 244 ENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRV-CQPP-- 300
Query: 712 AEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNG 771
D H R DN + G V Y CE GY + G + C G
Sbjct: 301 ----------PDVLHAERTQRDKDN------FSPGQEVFYSCEPGYDLRGAASMRCTPQG 344
Query: 772 QWSGTTPTCQYVDCGN-PGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQEN 830
WS PTC+ C + G++ NG+V P N GA + CDE ++L+G C
Sbjct: 345 DWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQL-GAKVDFVCDEGFQLKGSSASYCVLA 403
Query: 831 GT---WSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCE----RG--YNL 881
G W+ P+C++I CP P I G G +Y C+ RG ++L
Sbjct: 404 GMESLWNSSVPVCEQIFCPSPPV-IPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDL 462
Query: 882 KGHQTRTCIS----KGQWNGTVPVC-IPIDCRSPGNIENGKIVISNGSTLF--GSSVEYY 934
G T C S G W+ P C I C++P + K+ ++ F G+S++Y
Sbjct: 463 IGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYE 522
Query: 935 CLSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
C +Y PF CLD+ WS + C+
Sbjct: 523 CRPEYYG-RPFSITCLDNLVWSSPKDVCK 550
Score = 101 bits (243), Expect = 1e-20
Identities = 80/316 (25%), Positives = 124/316 (39%), Gaps = 42/316 (13%)
Query: 666 LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRS 725
+G+ + Y C Y P C + W+ + RC C +P +V V
Sbjct: 65 IGTYLNYECRPGYS-GRPFSIICLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKG--- 120
Query: 726 HGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTCQY 782
+ G+ +KY C KGY++IG S +TC +G W TP C
Sbjct: 121 -----------------IQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDR 163
Query: 783 VDCGNPGRIENGKVTLPSNATF-YGATAFYQCDEN------WELEGVIRRMCQEN----G 831
+ CG P I NG + F YG+ Y+C+ +EL G C N G
Sbjct: 164 IPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVG 223
Query: 832 TWSLEPPICKEITCPDPSAQIKAGSGLLVV--TSTLSIGGEAHYQCERGYNLKGHQTRTC 889
WS P C P+ +G+LV S S+ ++C+ G+ +KG + C
Sbjct: 224 IWSGPAPQC---IIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKC 280
Query: 890 ISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLF-GSSVEYYCLSQYQRVGPFLRK 948
+ +W +P C + C+ P ++ + + + G V Y C Y G +
Sbjct: 281 QALNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMR 339
Query: 949 CLDDGRWSGEEPSCEL 964
C G WS P+CE+
Sbjct: 340 CTPQGDWSPAAPTCEV 355
Score = 44.0 bits (99), Expect = 0.003
Identities = 17/42 (40%), Positives = 24/42 (57%)
Query: 17 NEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
+++N G Y C+ GY+L GA CT +GDW+ E P C
Sbjct: 1212 HQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGDWSPEAPRC 1253
Score = 42.7 bits (96), Expect = 0.007
Identities = 18/57 (31%), Positives = 28/57 (49%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C P + ++ +++N G Y C+ Y+L GA CT +GDW+ E P C
Sbjct: 1650 CQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCTPQGDWSPEAPRC 1706
Score = 42.3 bits (95), Expect = 0.009
Identities = 19/57 (33%), Positives = 28/57 (49%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C P +A + +++N G Y C+ GY+L GA CT +GDW+ P C
Sbjct: 297 CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTC 353
Score = 42.3 bits (95), Expect = 0.009
Identities = 19/57 (33%), Positives = 28/57 (49%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C P +A + +++N G Y C+ GY+L GA CT +GDW+ P C
Sbjct: 747 CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTC 803
Score = 37.5 bits (83), Expect = 0.26
Identities = 20/60 (33%), Positives = 27/60 (45%), Gaps = 5/60 (8%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGD---WTLEPPFC 58
C +P P N V + + I G+ Y C +GY L G+ C + GD W E P C
Sbjct: 104 CRNPPDPVNGMVHVI--KGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPIC 161
Score = 37.5 bits (83), Expect = 0.26
Identities = 20/60 (33%), Positives = 27/60 (45%), Gaps = 5/60 (8%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGD---WTLEPPFC 58
C P P N V + + I G+ Y C G+ L G EC L G+ W+ +PP C
Sbjct: 554 CKTPPDPVNGMVHVITD--IQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPIC 611
Score = 37.5 bits (83), Expect = 0.26
Identities = 20/60 (33%), Positives = 27/60 (45%), Gaps = 5/60 (8%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGD---WTLEPPFC 58
C P P N V + + I G+ Y C G+ L G EC L G+ W+ +PP C
Sbjct: 1004 CKTPPDPVNGMVHVITD--IQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPIC 1061
Score = 37.5 bits (83), Expect = 0.26
Identities = 19/60 (31%), Positives = 27/60 (45%), Gaps = 5/60 (8%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGD---WTLEPPFC 58
CG P P N V I + G+ Y C+EG+ L G+ C + G+ W + P C
Sbjct: 1457 CGPPPEPFNGMVHINTDTQF--GSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPIC 1514
>AL137789-2|CAI16044.1| 2039|Homo sapiens complement component (3b/4b)
receptor 1 (Knops blood group) protein.
Length = 2039
Score = 234 bits (573), Expect = 1e-60
Identities = 194/665 (29%), Positives = 275/665 (41%), Gaps = 78/665 (11%)
Query: 352 TCGSPDKLLNTTI-LGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDG---FWSGAPPSCK 407
+C +P +N + + D VGSRI Y C GH L+G S C G WS PP C+
Sbjct: 553 SCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQ 612
Query: 408 YVNCGGLTPIEDGDVALIDNRTTH-GARALYSC------RENFTLVGNPERTC--GDE-- 456
+ CG I +GD + H G+ Y C R+ F LVG P C D+
Sbjct: 613 RIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQV 672
Query: 457 GIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGSL---ASYTCENGHILSGSTSVTCTL 513
GIW G AP+C+ PP V N + + SL + C+ G ++ G V C
Sbjct: 673 GIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQA 732
Query: 514 GGAWSGVPPSCKYVNCGTP--TIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCN 571
W PSC V C P +H + G ++CEP Y L GA + C
Sbjct: 733 LNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCT 791
Query: 572 RDGKWSYDIPSCELTSCPE--PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQ 629
G WS P+CE+ SC + ++ +G + + + + ++F C+ G +L G C
Sbjct: 792 PQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCV 851
Query: 630 QDGE---WSGDSPTCEYIDCGKLPTLPYG--TMELLNGTTHLGSVIQYSCT------TNY 678
G W+ P CE I C P +P G T + L G + Y+C T++
Sbjct: 852 LAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLE-VFPFGKTVNYTCDPHPDRGTSF 910
Query: 679 RLVGPVRRTCTEEFQ----WSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTS 734
L+G CT + Q WS +PRC + G+ ++ H L
Sbjct: 911 DLIGESTIRCTSDPQGNGVWSSPAPRC----------------GILGHCQAPDHFLFAKL 954
Query: 735 DNRDVGNTYRIGALVKYRCEKGYKVIGESLS-TCEDNGQWSGTTPTCQYVDCGNPGRIEN 793
+ + + IG +KY C Y G S TC DN WS C+ C P N
Sbjct: 955 KTQTNASDFPIGTSLKYECRPEY--YGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVN 1012
Query: 794 GKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGT---WSLEPPICKEITCPDPSA 850
G V + ++ G+ Y C L G C +G WS +PPIC+ I C P
Sbjct: 1013 GMVHVITDIQV-GSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPCGLPPT 1071
Query: 851 QIKAGSGLLVVTSTLSIGGEAHYQCERG------YNLKGHQTRTCISK----GQWNGTVP 900
I G + G Y+C G + L G + C S G W+G P
Sbjct: 1072 -IANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAP 1130
Query: 901 VC-IPIDCRSPGNIENGKIVISNGSTLFGSS--VEYYCLSQYQRVGPFLRKCLDDGRWSG 957
C IP C +P N+ENG I++S+ +LF + VE+ C + GP KC +W
Sbjct: 1131 QCIIPNKC-TPPNVENG-ILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEP 1188
Query: 958 EEPSC 962
E PSC
Sbjct: 1189 ELPSC 1193
Score = 227 bits (555), Expect = 2e-58
Identities = 187/662 (28%), Positives = 274/662 (41%), Gaps = 69/662 (10%)
Query: 352 TCGSPDKLLNTTI-LGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDG---FWSGAPPSCK 407
+C +P +N + + D VGSRI Y C GH L+G S C G WS PP C+
Sbjct: 1003 SCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQ 1062
Query: 408 YVNCGGLTPIEDGDVALIDNRTTH-GARALYSC------RENFTLVGNPERTC--GDE-- 456
+ CG I +GD + H G+ Y C R+ F LVG P C D+
Sbjct: 1063 RIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQV 1122
Query: 457 GIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGSL---ASYTCENGHILSGSTSVTCTL 513
GIW G AP+C+ PP V N + + SL + C+ G ++ G V C
Sbjct: 1123 GIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQA 1182
Query: 514 GGAWSGVPPSCKYVNCGTPTIHKGSFVLINGTT-TYGSIAQFTCEPDYWLNGAEELVCNR 572
W PSC V P I G + + G ++CEP Y L GA L C
Sbjct: 1183 LNKWEPELPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTP 1242
Query: 573 DGKWSYDIPSCELTSCPE--PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQ 630
G WS + P C + SC + ++P G + + + + ++F C+ G +L G C
Sbjct: 1243 QGDWSPEAPRCAVKSCDDFLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCVL 1302
Query: 631 DGE---WSGDSPTCEYIDCGKLPTLPYGT-MELLNGTTHLGSVIQYSCTTN------YRL 680
G W+ P CE+I C P + G +G G I Y+C + + L
Sbjct: 1303 VGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNL 1362
Query: 681 VGPVRRTCTEEFQ----WSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDN 736
+G CT + WS +PRCE ++ ++ T I +D
Sbjct: 1363 IGESTIRCTSDPHGNGVWSSPAPRCE--------LSVRAGHCKTPEQFPFASPTIPINDF 1414
Query: 737 RDVGNTYRIGALVKYRCEKGYKVIGESLS-TCEDNGQWSGTTPTCQYVDCGNPGRIENGK 795
+ +G + Y C GY G+ S +C +N WS C+ CG P NG
Sbjct: 1415 E-----FPVGTSLNYECRPGY--FGKMFSISCLENLVWSSVEDNCRRKSCGPPPEPFNGM 1467
Query: 796 VTLPSNATFYGATAFYQCDENWELEGVIRRMCQENG---TWSLEPPICKEITCPDPSAQI 852
V + ++ T +G+T Y C+E + L G C +G TW + PIC+ I+C +P I
Sbjct: 1468 VHINTD-TQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISC-EPPPTI 1525
Query: 853 KAGSGLLVVTSTLSIGGEAHYQCERG------YNLKGHQTRTCISK----GQWNGTVPVC 902
G ++ G YQC G + L G ++ C SK G W+ P C
Sbjct: 1526 SNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRC 1585
Query: 903 IPID-CRSPGNIENGKIVISNGSTL-FGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEP 960
I + C +P +EN V N S + + C + VG +C +GRW + P
Sbjct: 1586 ISTNKCTAP-EVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLP 1644
Query: 961 SC 962
C
Sbjct: 1645 HC 1646
Score = 224 bits (547), Expect = 2e-57
Identities = 175/645 (27%), Positives = 261/645 (40%), Gaps = 74/645 (11%)
Query: 368 DYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDN 427
++ +G+ + Y+C G+ S C K+ W+GA C+ +C +G V +I
Sbjct: 62 EFPIGTYLNYECRPGYSGR-PFSIICLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKG 120
Query: 428 RTTHGARALYSCRENFTLVGNPERTC---GDEGIWDGEAPRCLFDWCPDPPAVSNA---S 481
G++ YSC + + L+G+ TC GD IWD E P C C PP ++N S
Sbjct: 121 -IQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTITNGDFIS 179
Query: 482 VTVNGHKAGSLASYTCENG------HILSGSTSVTCTLG----GAWSGVPPSCKYVN-CG 530
GS+ +Y C G L G S+ CT G WSG P C N C
Sbjct: 180 TNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCT 239
Query: 531 TPTIHKGSFVLINGTT-TYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCP 589
P + G V N + + + +F C+P + + G + C KW ++PSC P
Sbjct: 240 PPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQP 299
Query: 590 EPEV--PSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCG 647
P+V + ++ + + CE G+ L G ++ C G+WS +PTCE C
Sbjct: 300 PPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCD 359
Query: 648 KLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCT---EEFQWSDSSPRCEEI 704
L LG+ + + C ++L G C E W+ S P CE+I
Sbjct: 360 DFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQI 419
Query: 705 RCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCE------KGYK 758
C P V N R G L + G V Y C+ +
Sbjct: 420 FCPSP--------PVIPNGRHTGKPL----------EVFPFGKTVNYTCDPHPDRGTSFD 461
Query: 759 VIGESLSTC----EDNGQWSGTTPTCQYV-DCGNPGRIENGKVTLPSNATFY--GATAFY 811
+IGES C + NG WS P C + C P K+ +NA+ + G + Y
Sbjct: 462 LIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKY 521
Query: 812 QCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEA 871
+C + C +N WS +CK +C P + +G++ V + + +G
Sbjct: 522 ECRPEY-YGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPV---NGMVHVITDIQVGSRI 577
Query: 872 HYQCERGYNLKGHQTRTCISKG---QWNGTVPVCIPIDCRSPGNIENGKIVISNGSTL-F 927
+Y C G+ L GH + CI G W+ P+C I C P I NG + +N +
Sbjct: 578 NYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHY 637
Query: 928 GSSVEYYC------LSQYQRVGPFLRKCL--DD--GRWSGEEPSC 962
GS V Y C ++ VG C DD G WSG P C
Sbjct: 638 GSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQC 682
Score = 221 bits (541), Expect = 8e-57
Identities = 188/665 (28%), Positives = 271/665 (40%), Gaps = 78/665 (11%)
Query: 352 TCGSPDKLLNTTI-LGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDG---FWSGAPPSCK 407
+C +P +N + + GS+I Y C +G+ L+G S C G W P C
Sbjct: 103 SCRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICD 162
Query: 408 YVNCGGLTPIEDGDVALIDNRTTH-GARALYSC------RENFTLVGNPERTC--GDE-- 456
+ CG I +GD + H G+ Y C R+ F LVG P C D+
Sbjct: 163 RIPCGLPPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQV 222
Query: 457 GIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGSL---ASYTCENGHILSGSTSVTCTL 513
GIW G AP+C+ PP V N + + SL + C+ G ++ G V C
Sbjct: 223 GIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQA 282
Query: 514 GGAWSGVPPSCKYVNCGTP--TIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCN 571
W PSC V C P +H + G ++CEP Y L GA + C
Sbjct: 283 LNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCT 341
Query: 572 RDGKWSYDIPSCELTSCPE--PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQ 629
G WS P+CE+ SC + ++ +G + + + + ++F C+ G +L G C
Sbjct: 342 PQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCV 401
Query: 630 QDGE---WSGDSPTCEYIDCGKLPTLPYG--TMELLNGTTHLGSVIQYSCT------TNY 678
G W+ P CE I C P +P G T + L G + Y+C T++
Sbjct: 402 LAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLE-VFPFGKTVNYTCDPHPDRGTSF 460
Query: 679 RLVGPVRRTCTEEFQ----WSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTS 734
L+G CT + Q WS +PRC + G+ ++ H L
Sbjct: 461 DLIGESTIRCTSDPQGNGVWSSPAPRC----------------GILGHCQAPDHFLFAKL 504
Query: 735 DNRDVGNTYRIGALVKYRCEKGYKVIGESLS-TCEDNGQWSGTTPTCQYVDCGNPGRIEN 793
+ + + IG +KY C Y G S TC DN WS C+ C P N
Sbjct: 505 KTQTNASDFPIGTSLKYECRPEY--YGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVN 562
Query: 794 GKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGT---WSLEPPICKEITCPDPSA 850
G V + ++ G+ Y C L G C +G WS +PPIC+ I C P
Sbjct: 563 GMVHVITDIQV-GSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPT 621
Query: 851 QIKAGSGLLVVTSTLSIGGEAHYQCERG------YNLKGHQTRTCISK----GQWNGTVP 900
I G + G Y+C G + L G + C S G W+G P
Sbjct: 622 -IANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAP 680
Query: 901 VC-IPIDCRSPGNIENGKIVISNGSTLFGSS--VEYYCLSQYQRVGPFLRKCLDDGRWSG 957
C IP C +P N+ENG I++S+ +LF + VE+ C + GP KC +W
Sbjct: 681 QCIIPNKC-TPPNVENG-ILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEP 738
Query: 958 EEPSC 962
E PSC
Sbjct: 739 ELPSC 743
Score = 205 bits (501), Expect = 6e-52
Identities = 178/668 (26%), Positives = 269/668 (40%), Gaps = 72/668 (10%)
Query: 353 CGSPDKLL----NTTILGNDYDVGSRIVYKC-PEGHMLLGDKSRHCKKDGFWSGAPPSCK 407
C +PD L T +D+ +G+ + Y+C PE + S C + WS CK
Sbjct: 943 CQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGR--PFSITCLDNLVWSSPKDVCK 1000
Query: 408 YVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTC---GDEGIWDGEAP 464
+C +G V +I + G+R YSC L+G+ C G+ W + P
Sbjct: 1001 RKSCKTPPDPVNGMVHVITDIQV-GSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPP 1059
Query: 465 RCLFDWCPDPPAVSNAS-VTVNGHKA--GSLASYTCENGHI------LSGSTSVTCTLG- 514
C C PP ++N ++ N GS+ +Y C G L G S+ CT
Sbjct: 1060 ICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSND 1119
Query: 515 ---GAWSGVPPSCKYVN-CGTPTIHKGSFVLINGTT-TYGSIAQFTCEPDYWLNGAEELV 569
G WSG P C N C P + G V N + + + +F C+P + + G +
Sbjct: 1120 DQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVK 1179
Query: 570 CNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAF--DYYVHSTINFHCEAGHKLIGEPNLV 627
C KW ++PSC P PE+ G + + ++ + + CE G+ L G +L
Sbjct: 1180 CQALNKWEPELPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLH 1239
Query: 628 CQQDGEWSGDSPTCEYIDCGK-LPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRR 686
C G+WS ++P C C L LP+G + L LG+ + + C +RL G
Sbjct: 1240 CTPQGDWSPEAPRCAVKSCDDFLGQLPHGRV-LFPLNLQLGAKVSFVCDEGFRLKGSSVS 1298
Query: 687 TCT---EEFQWSDSSPRCEEIRCSDP-IVAEKSIVSVTGNDRSHGHTLIRTSD-NRDVGN 741
C W++S P CE I C +P + D +G + T D + D G
Sbjct: 1299 HCVLVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGM 1358
Query: 742 TYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYV----DCGNPGRIENGKVT 797
T+ + RC S NG WS P C+ C P + T
Sbjct: 1359 TFNLIGESTIRCT----------SDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPT 1408
Query: 798 LPSNATFY--GATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAG 855
+P N + G + Y+C + + C EN WS C+ +C P
Sbjct: 1409 IPINDFEFPVGTSLNYECRPGY-FGKMFSISCLENLVWSSVEDNCRRKSCGPPPEPF--- 1464
Query: 856 SGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQ---WNGTVPVCIPIDCRSPGN 912
+G++ + + G +Y C G+ L G + TC+ G W+ P+C I C P
Sbjct: 1465 NGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPT 1524
Query: 913 IENGKIVISNGSTLF--GSSVEYYCLS------QYQRVGPFLRKCL--DD--GRWSGEEP 960
I NG SN T F G+ V Y C + ++ VG C DD G WS P
Sbjct: 1525 ISNGDF-YSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPP 1583
Query: 961 SCELATNE 968
C ++TN+
Sbjct: 1584 RC-ISTNK 1590
Score = 200 bits (488), Expect = 2e-50
Identities = 170/650 (26%), Positives = 256/650 (39%), Gaps = 79/650 (12%)
Query: 371 VGSRIVYKCPEGHMLLGDKSRHCKKDGF---WSGAPPSCKYVNCGGLTPIEDG-DVALID 426
+G+++ + C EG L G HC G W+ + P C+++ C I +G
Sbjct: 1278 LGAKVSFVCDEGFRLKGSSVSHCVLVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPS 1337
Query: 427 NRTTHGARALYSCREN------FTLVGNPERTCGDE----GIWDGEAPRCLFD----WCP 472
+G Y+C + F L+G C + G+W APRC C
Sbjct: 1338 GDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTSDPHGNGVWSSPAPRCELSVRAGHCK 1397
Query: 473 DPPAVSNASVTV--NGHK--AGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVN 528
P AS T+ N + G+ +Y C G+ S++C WS V +C+ +
Sbjct: 1398 TPEQFPFASPTIPINDFEFPVGTSLNYECRPGYF-GKMFSISCLENLVWSSVEDNCRRKS 1456
Query: 529 CGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGK---WSYDIPSCEL 585
CG P V IN T +GS ++C + L G+ C G W P CE+
Sbjct: 1457 CGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEI 1516
Query: 586 TSC-PEPEVPSGGYM--EAFDYYVHSTINFHCEAG------HKLIGEPNLVC----QQDG 632
SC P P + +G + ++ + + + C G +L+GE ++ C Q G
Sbjct: 1517 ISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVG 1576
Query: 633 EWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTH-LGSVIQYSCTTNYRLVGPVRRTCTEE 691
WS P C + P + N + L +I++ C + +VG C
Sbjct: 1577 VWSSPPPRCISTNKCTAPEVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTN 1636
Query: 692 FQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKY 751
+W P C + C P + HG + DN + G V Y
Sbjct: 1637 GRWGPKLPHCSRV-CQPP------------PEILHGEHTLSHQDN------FSPGQEVFY 1677
Query: 752 RCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGN-PGRIENGKVTLPSNATFYGATAF 810
CE Y + G + C G WS P C C + G++ +G+V LP N GA
Sbjct: 1678 SCEPSYDLRGAASLHCTPQGDWSPEAPRCTVKSCDDFLGQLPHGRVLLPLNLQL-GAKVS 1736
Query: 811 YQCDENWELEGVIRRMCQENG---TWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSI 867
+ CDE + L+G C G W+ P+C++I CP+P A I G +
Sbjct: 1737 FVCDEGFRLKGRSASHCVLAGMKALWNSSVPVCEQIFCPNPPA-ILNGRHTGTPFGDIPY 1795
Query: 868 GGEAHYQC----ERG--YNLKGHQTRTCIS----KGQWNGTVPVC---IPIDCRSPGNIE 914
G E Y C +RG +NL G + C S G W+ P C +P C P I+
Sbjct: 1796 GKEISYACDTHPDRGMTFNLIGESSIRCTSDPQGNGVWSSPAPRCELSVPAACPHPPKIQ 1855
Query: 915 NGKIVISNGST-LFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
NG + + S L G ++ Y C Y VG C D G WS + C+
Sbjct: 1856 NGHYIGGHVSLYLPGMTISYICDPGYLLVGKGFIFCTDQGIWSQLDHYCK 1905
Score = 197 bits (480), Expect = 2e-49
Identities = 174/678 (25%), Positives = 274/678 (40%), Gaps = 90/678 (13%)
Query: 345 ICQYLPPTCGSPDKLLNTTILGND---YDVGSRIVYKCPEGH------MLLGDKSRHCKK 395
IC +P CG P + N + + + GS + Y+C G L+G+ S +C
Sbjct: 160 ICDRIP--CGLPPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTS 217
Query: 396 D----GFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRTTHGARAL--YSCRENFTLVGNP 449
+ G WSG P C N +E+G + + DNR+ + + C+ F + G
Sbjct: 218 NDDQVGIWSGPAPQCIIPNKCTPPNVENG-ILVSDNRSLFSLNEVVEFRCQPGFVMKGPR 276
Query: 450 ERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTV---NGHKAGSLASYTCENGHILSGS 506
C W+ E P C C PP V +A T + G Y+CE G+ L G+
Sbjct: 277 RVKCQALNKWEPELPSCS-RVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGA 335
Query: 507 TSVTCTLGGAWSGVPPSCKYVNCGT--PTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNG 564
S+ CT G WS P+C+ +C + G VL G+ F C+ + L G
Sbjct: 336 ASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGR-VLFPVNLQLGAKVDFVCDEGFQLKG 394
Query: 565 AEELVC---NRDGKWSYDIPSCELTSCPEPEV-PSGGY----MEAFDYYVHSTINFHCE- 615
+ C + W+ +P CE CP P V P+G + +E F + T+N+ C+
Sbjct: 395 SSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPF--GKTVNYTCDP 452
Query: 616 -----AGHKLIGEPNLVCQQD----GEWSGDSPTCEYIDCGKLPT-LPYGTMELLNGTTH 665
LIGE + C D G WS +P C + + P + ++ +
Sbjct: 453 HPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASD 512
Query: 666 --LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGND 723
+G+ ++Y C Y P TC + WS C+ C P D
Sbjct: 513 FPIGTSLKYECRPEY-YGRPFSITCLDNLVWSSPKDVCKRKSCKTP------------PD 559
Query: 724 RSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTC 780
+G + T D+ ++G+ + Y C G+++IG S + C +G WS P C
Sbjct: 560 PVNGMVHVIT----DI----QVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPIC 611
Query: 781 QYVDCGNPGRIENGKVTLPSNATF-YGATAFYQCDEN------WELEGVIRRMCQEN--- 830
Q + CG P I NG + F YG+ Y+C+ +EL G C N
Sbjct: 612 QRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQ 671
Query: 831 -GTWSLEPPICKEITCPDPSAQIKAGSGLLVVT--STLSIGGEAHYQCERGYNLKGHQTR 887
G WS P C P+ +G+LV S S+ ++C+ G+ +KG +
Sbjct: 672 VGIWSGPAPQC---IIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRV 728
Query: 888 TCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLF-GSSVEYYCLSQYQRVGPFL 946
C + +W +P C + C+ P ++ + + + G V Y C Y G
Sbjct: 729 KCQALNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAAS 787
Query: 947 RKCLDDGRWSGEEPSCEL 964
+C G WS P+CE+
Sbjct: 788 MRCTPQGDWSPAAPTCEV 805
Score = 196 bits (479), Expect = 3e-49
Identities = 181/674 (26%), Positives = 263/674 (39%), Gaps = 82/674 (12%)
Query: 353 CGSPDKLLNTTILGNDYDV---GSRIVYKC---PE---GHMLLGDKSRHCKKD----GFW 399
C SP + N G +V G + Y C P+ L+G+ + C D G W
Sbjct: 871 CPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVW 930
Query: 400 SGAPPSCKYV-NCGGLTPIEDGDVALIDNRTTH--GARALYSCRENFTLVGNP-ERTCGD 455
S P C + +C + N + G Y CR + G P TC D
Sbjct: 931 SSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEY--YGRPFSITCLD 988
Query: 456 EGIWDGEAPRCLFDWCPDPPAVSNASV-TVNGHKAGSLASYTCENGHILSGSTSVTCTLG 514
+W C C PP N V + + GS +Y+C GH L G +S C L
Sbjct: 989 NLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILS 1048
Query: 515 GA---WSGVPPSCKYVNCGTP-TIHKGSFVLINGTTT-YGSIAQFTCEPD------YWLN 563
G WS PP C+ + CG P TI G F+ N YGS+ + C + L
Sbjct: 1049 GNTAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELV 1108
Query: 564 GAEELVC--NRD--GKWSYDIPSCELTS-CPEPEVPSGGYMEAFD--YYVHSTINFHCEA 616
G + C N D G WS P C + + C P V +G + + ++ + F C+
Sbjct: 1109 GEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQP 1168
Query: 617 GHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHL-GSVIQYSCT 675
G + G + CQ +W + P+C + C P + +G + G + YSC
Sbjct: 1169 GFVMKGPRRVKCQALNKWEPELPSCSRV-CQPPPEILHGEHTPSHQDNFSPGQEVFYSCE 1227
Query: 676 TNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSD 735
Y L G CT + WS +PRC C D + HG L +
Sbjct: 1228 PGYDLRGAASLHCTPQGDWSPEAPRCAVKSCDDFL-----------GQLPHGRVLFPLN- 1275
Query: 736 NRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTCQYVDCGNPGRIE 792
++GA V + C++G+++ G S+S C G W+ + P C+++ C NP I
Sbjct: 1276 -------LQLGAKVSFVCDEGFRLKGSSVSHCVLVGMRSLWNNSVPVCEHIFCPNPPAIL 1328
Query: 793 NGKVT-LPSNATFYGATAFYQCDEN------WELEGVIRRMCQE----NGTWSLEPPICK 841
NG+ T PS YG Y CD + + L G C NG WS P C+
Sbjct: 1329 NGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTSDPHGNGVWSSPAPRCE 1388
Query: 842 EIT----CPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNG 897
C P A + + +G +Y+C GY K +C+ W+
Sbjct: 1389 LSVRAGHCKTPEQFPFASPTIPINDFEFPVGTSLNYECRPGYFGKMFSI-SCLENLVWSS 1447
Query: 898 TVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGR--- 954
C C P NG + I N T FGS+V Y C ++ +G CL G
Sbjct: 1448 VEDNCRRKSCGPPPEPFNGMVHI-NTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVT 1506
Query: 955 WSGEEPSCELATNE 968
W + P CE+ + E
Sbjct: 1507 WDKKAPICEIISCE 1520
Score = 196 bits (477), Expect = 5e-49
Identities = 186/688 (27%), Positives = 271/688 (39%), Gaps = 83/688 (12%)
Query: 345 ICQYLPPTCGSPDKLLNTTILGN---DYDVGSRIVYKC---PEGHM---LLGDKSRHCKK 395
+C+++ C +P +LN G D G I Y C P+ M L+G+ + C
Sbjct: 1315 VCEHI--FCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTS 1372
Query: 396 D----GFWSGAPPSCKY-VNCGGLT-----PIEDGDVALIDNRTTHGARALYSCRENFTL 445
D G WS P C+ V G P + + D G Y CR +
Sbjct: 1373 DPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDFEFPVGTSLNYECRPGY-- 1430
Query: 446 VGNP-ERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGH-KAGSLASYTCENGHIL 503
G +C + +W C C PP N V +N + GS +Y+C G L
Sbjct: 1431 FGKMFSISCLENLVWSSVEDNCRRKSCGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRL 1490
Query: 504 SGSTSVTCTLGG---AWSGVPPSCKYVNCGTP-TIHKGSFVLINGTTTY-GSIAQFTCE- 557
GS S TC + G W P C+ ++C P TI G F N T+ + G++ + C
Sbjct: 1491 IGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHT 1550
Query: 558 -PD----YWLNGAEELVC-NRD---GKWSYDIPSCELTS-CPEPEVPSGGYMEAFDYYVH 607
PD + L G + C ++D G WS P C T+ C PEV + + +
Sbjct: 1551 GPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRCISTNKCTAPEVENAIRVPGNRSFFT 1610
Query: 608 ST--INFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTH 665
T I F C+ G ++G + CQ +G W P C + C P + +G L +
Sbjct: 1611 LTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHCSRV-CQPPPEILHGEHTLSHQDNF 1669
Query: 666 L-GSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDR 724
G + YSC +Y L G CT + WS +PRC C D +
Sbjct: 1670 SPGQEVFYSCEPSYDLRGAASLHCTPQGDWSPEAPRCTVKSCDDFL-----------GQL 1718
Query: 725 SHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTCQ 781
HG L+ + ++GA V + C++G+++ G S S C G W+ + P C+
Sbjct: 1719 PHGRVLLPLN--------LQLGAKVSFVCDEGFRLKGRSASHCVLAGMKALWNSSVPVCE 1770
Query: 782 YVDCGNPGRIENGKVT-LPSNATFYGATAFYQCDEN------WELEGVIRRMC----QEN 830
+ C NP I NG+ T P YG Y CD + + L G C Q N
Sbjct: 1771 QIFCPNPPAILNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGESSIRCTSDPQGN 1830
Query: 831 GTWSLEPPICK---EITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTR 887
G WS P C+ CP P +I+ G + S G Y C+ GY L G
Sbjct: 1831 GVWSSPAPRCELSVPAACPHPP-KIQNGHYIGGHVSLYLPGMTISYICDPGYLLVGKGFI 1889
Query: 888 TCISKGQWNGTVPVCIPIDCRSPGNIEN-GKIVISNGSTLFGSSVEYYCLSQYQRVGPFL 946
C +G W+ C ++C P + K + +G V C Y G
Sbjct: 1890 FCTDQGIWSQLDHYCKEVNCSFPLFMNGISKELEMKKVYHYGDYVTLKCEDGYTLEGSPW 1949
Query: 947 RKCLDDGRWSGEEPSCELATNEAVDSGT 974
+C D RW C T++A+ GT
Sbjct: 1950 SQCQADDRWDPPLAKCTSRTHDALIVGT 1977
Score = 190 bits (462), Expect = 3e-47
Identities = 174/666 (26%), Positives = 263/666 (39%), Gaps = 79/666 (11%)
Query: 353 CGSPDKLLNTTILGNDYDV---GSRIVYKC---PE---GHMLLGDKSRHCKKD----GFW 399
C SP + N G +V G + Y C P+ L+G+ + C D G W
Sbjct: 421 CPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVW 480
Query: 400 SGAPPSCKYV-NCGGLTPIEDGDVALIDNRTTH--GARALYSCRENFTLVGNP-ERTCGD 455
S P C + +C + N + G Y CR + G P TC D
Sbjct: 481 SSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEY--YGRPFSITCLD 538
Query: 456 EGIWDGEAPRCLFDWCPDPPAVSNASV-TVNGHKAGSLASYTCENGHILSGSTSVTCTLG 514
+W C C PP N V + + GS +Y+C GH L G +S C L
Sbjct: 539 NLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILS 598
Query: 515 GA---WSGVPPSCKYVNCGTP-TIHKGSFVLINGTTT-YGSIAQFTCEPD------YWLN 563
G WS PP C+ + CG P TI G F+ N YGS+ + C P + L
Sbjct: 599 GNAAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELV 658
Query: 564 GAEELVC--NRD--GKWSYDIPSCELTS-CPEPEVPSGGYMEAFD--YYVHSTINFHCEA 616
G + C N D G WS P C + + C P V +G + + ++ + F C+
Sbjct: 659 GEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQP 718
Query: 617 GHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHL-GSVIQYSCT 675
G + G + CQ +W + P+C + C P + + + G + YSC
Sbjct: 719 GFVMKGPRRVKCQALNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCE 777
Query: 676 TNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSD 735
Y L G CT + WS ++P CE C D + +G L +
Sbjct: 778 PGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDFM-----------GQLLNGRVLFPVN- 825
Query: 736 NRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTCQYVDCGNPGRIE 792
++GA V + C++G+++ G S S C G W+ + P C+ + C +P I
Sbjct: 826 -------LQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIP 878
Query: 793 NGKVT-LPSNATFYGATAFYQCD------ENWELEGVIRRMC----QENGTWSLEPPICK 841
NG+ T P +G T Y CD +++L G C Q NG WS P C
Sbjct: 879 NGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCG 938
Query: 842 EI-TCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVP 900
+ C P + A S IG Y+C Y + TC+ W+
Sbjct: 939 ILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGRPFSI-TCLDNLVWSSPKD 997
Query: 901 VCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDG---RWSG 957
VC C++P + NG + + + GS + Y C + ++ +G +C+ G WS
Sbjct: 998 VCKRKSCKTPPDPVNGMVHVITDIQV-GSRINYSCTTGHRLIGHSSAECILSGNTAHWST 1056
Query: 958 EEPSCE 963
+ P C+
Sbjct: 1057 KPPICQ 1062
Score = 169 bits (411), Expect = 5e-41
Identities = 135/509 (26%), Positives = 209/509 (41%), Gaps = 59/509 (11%)
Query: 490 GSLASYTCENGHILSGST-SVTCTLGGAWSGVPPSCKYVNCGTPTIHKGSFVLINGTTTY 548
G+ +Y C G+ SG S+ C W+G C+ +C P V + +
Sbjct: 66 GTYLNYECRPGY--SGRPFSIICLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKGIQF 123
Query: 549 GSIAQFTCEPDYWLNGAEELVCNRDGK---WSYDIPSCELTSCP-EPEVPSGGYMEAF-- 602
GS +++C Y L G+ C G W + P C+ C P + +G ++
Sbjct: 124 GSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTITNGDFISTNRE 183
Query: 603 DYYVHSTINFHCEAGH------KLIGEPNLVC----QQDGEWSGDSPTCEYIDCGKLPTL 652
+++ S + + C G +L+GEP++ C Q G WSG +P C + P +
Sbjct: 184 NFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNV 243
Query: 653 PYGTMELLNGTTH-LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIV 711
G + N + L V+++ C + + GP R C +W P C + C P
Sbjct: 244 ENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRV-CQPP-- 300
Query: 712 AEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNG 771
D H R DN + G V Y CE GY + G + C G
Sbjct: 301 ----------PDVLHAERTQRDKDN------FSPGQEVFYSCEPGYDLRGAASMRCTPQG 344
Query: 772 QWSGTTPTCQYVDCGN-PGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQEN 830
WS PTC+ C + G++ NG+V P N GA + CDE ++L+G C
Sbjct: 345 DWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQL-GAKVDFVCDEGFQLKGSSASYCVLA 403
Query: 831 GT---WSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCE----RG--YNL 881
G W+ P+C++I CP P I G G +Y C+ RG ++L
Sbjct: 404 GMESLWNSSVPVCEQIFCPSPPV-IPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDL 462
Query: 882 KGHQTRTCIS----KGQWNGTVPVC-IPIDCRSPGNIENGKIVISNGSTLF--GSSVEYY 934
G T C S G W+ P C I C++P + K+ ++ F G+S++Y
Sbjct: 463 IGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYE 522
Query: 935 CLSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
C +Y PF CLD+ WS + C+
Sbjct: 523 CRPEYYG-RPFSITCLDNLVWSSPKDVCK 550
Score = 101 bits (243), Expect = 1e-20
Identities = 80/316 (25%), Positives = 124/316 (39%), Gaps = 42/316 (13%)
Query: 666 LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRS 725
+G+ + Y C Y P C + W+ + RC C +P +V V
Sbjct: 65 IGTYLNYECRPGYS-GRPFSIICLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKG--- 120
Query: 726 HGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTCQY 782
+ G+ +KY C KGY++IG S +TC +G W TP C
Sbjct: 121 -----------------IQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDR 163
Query: 783 VDCGNPGRIENGKVTLPSNATF-YGATAFYQCDEN------WELEGVIRRMCQEN----G 831
+ CG P I NG + F YG+ Y+C+ +EL G C N G
Sbjct: 164 IPCGLPPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVG 223
Query: 832 TWSLEPPICKEITCPDPSAQIKAGSGLLVV--TSTLSIGGEAHYQCERGYNLKGHQTRTC 889
WS P C P+ +G+LV S S+ ++C+ G+ +KG + C
Sbjct: 224 IWSGPAPQC---IIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKC 280
Query: 890 ISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLF-GSSVEYYCLSQYQRVGPFLRK 948
+ +W +P C + C+ P ++ + + + G V Y C Y G +
Sbjct: 281 QALNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMR 339
Query: 949 CLDDGRWSGEEPSCEL 964
C G WS P+CE+
Sbjct: 340 CTPQGDWSPAAPTCEV 355
Score = 44.0 bits (99), Expect = 0.003
Identities = 17/42 (40%), Positives = 24/42 (57%)
Query: 17 NEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
+++N G Y C+ GY+L GA CT +GDW+ E P C
Sbjct: 1212 HQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGDWSPEAPRC 1253
Score = 42.7 bits (96), Expect = 0.007
Identities = 18/57 (31%), Positives = 28/57 (49%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C P + ++ +++N G Y C+ Y+L GA CT +GDW+ E P C
Sbjct: 1650 CQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCTPQGDWSPEAPRC 1706
Score = 42.3 bits (95), Expect = 0.009
Identities = 19/57 (33%), Positives = 28/57 (49%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C P +A + +++N G Y C+ GY+L GA CT +GDW+ P C
Sbjct: 297 CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTC 353
Score = 42.3 bits (95), Expect = 0.009
Identities = 19/57 (33%), Positives = 28/57 (49%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C P +A + +++N G Y C+ GY+L GA CT +GDW+ P C
Sbjct: 747 CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTC 803
Score = 37.5 bits (83), Expect = 0.26
Identities = 20/60 (33%), Positives = 27/60 (45%), Gaps = 5/60 (8%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGD---WTLEPPFC 58
C +P P N V + + I G+ Y C +GY L G+ C + GD W E P C
Sbjct: 104 CRNPPDPVNGMVHVI--KGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPIC 161
Score = 37.5 bits (83), Expect = 0.26
Identities = 20/60 (33%), Positives = 27/60 (45%), Gaps = 5/60 (8%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGD---WTLEPPFC 58
C P P N V + + I G+ Y C G+ L G EC L G+ W+ +PP C
Sbjct: 554 CKTPPDPVNGMVHVITD--IQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPIC 611
Score = 37.5 bits (83), Expect = 0.26
Identities = 20/60 (33%), Positives = 27/60 (45%), Gaps = 5/60 (8%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGD---WTLEPPFC 58
C P P N V + + I G+ Y C G+ L G EC L G+ W+ +PP C
Sbjct: 1004 CKTPPDPVNGMVHVITD--IQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPIC 1061
Score = 37.5 bits (83), Expect = 0.26
Identities = 19/60 (31%), Positives = 27/60 (45%), Gaps = 5/60 (8%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGD---WTLEPPFC 58
CG P P N V I + G+ Y C+EG+ L G+ C + G+ W + P C
Sbjct: 1457 CGPPPEPFNGMVHINTDTQF--GSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPIC 1514
>AL137789-1|CAI16043.1| 2039|Homo sapiens complement component (3b/4b)
receptor 1 (Knops blood group) protein.
Length = 2039
Score = 234 bits (573), Expect = 1e-60
Identities = 194/665 (29%), Positives = 275/665 (41%), Gaps = 78/665 (11%)
Query: 352 TCGSPDKLLNTTI-LGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDG---FWSGAPPSCK 407
+C +P +N + + D VGSRI Y C GH L+G S C G WS PP C+
Sbjct: 553 SCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQ 612
Query: 408 YVNCGGLTPIEDGDVALIDNRTTH-GARALYSC------RENFTLVGNPERTC--GDE-- 456
+ CG I +GD + H G+ Y C R+ F LVG P C D+
Sbjct: 613 RIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQV 672
Query: 457 GIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGSL---ASYTCENGHILSGSTSVTCTL 513
GIW G AP+C+ PP V N + + SL + C+ G ++ G V C
Sbjct: 673 GIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQA 732
Query: 514 GGAWSGVPPSCKYVNCGTP--TIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCN 571
W PSC V C P +H + G ++CEP Y L GA + C
Sbjct: 733 LNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCT 791
Query: 572 RDGKWSYDIPSCELTSCPE--PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQ 629
G WS P+CE+ SC + ++ +G + + + + ++F C+ G +L G C
Sbjct: 792 PQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCV 851
Query: 630 QDGE---WSGDSPTCEYIDCGKLPTLPYG--TMELLNGTTHLGSVIQYSCT------TNY 678
G W+ P CE I C P +P G T + L G + Y+C T++
Sbjct: 852 LAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLE-VFPFGKAVNYTCDPHPDRGTSF 910
Query: 679 RLVGPVRRTCTEEFQ----WSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTS 734
L+G CT + Q WS +PRC + G+ ++ H L
Sbjct: 911 DLIGESTIRCTSDPQGNGVWSSPAPRC----------------GILGHCQAPDHFLFAKL 954
Query: 735 DNRDVGNTYRIGALVKYRCEKGYKVIGESLS-TCEDNGQWSGTTPTCQYVDCGNPGRIEN 793
+ + + IG +KY C Y G S TC DN WS C+ C P N
Sbjct: 955 KTQTNASDFPIGTSLKYECRPEY--YGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVN 1012
Query: 794 GKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGT---WSLEPPICKEITCPDPSA 850
G V + ++ G+ Y C L G C +G WS +PPIC+ I C P
Sbjct: 1013 GMVHVITDIQV-GSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPCGLPPT 1071
Query: 851 QIKAGSGLLVVTSTLSIGGEAHYQCERG------YNLKGHQTRTCISK----GQWNGTVP 900
I G + G Y+C G + L G + C S G W+G P
Sbjct: 1072 -IANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAP 1130
Query: 901 VC-IPIDCRSPGNIENGKIVISNGSTLFGSS--VEYYCLSQYQRVGPFLRKCLDDGRWSG 957
C IP C +P N+ENG I++S+ +LF + VE+ C + GP KC +W
Sbjct: 1131 QCIIPNKC-TPPNVENG-ILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEP 1188
Query: 958 EEPSC 962
E PSC
Sbjct: 1189 ELPSC 1193
Score = 227 bits (555), Expect = 2e-58
Identities = 187/662 (28%), Positives = 274/662 (41%), Gaps = 69/662 (10%)
Query: 352 TCGSPDKLLNTTI-LGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDG---FWSGAPPSCK 407
+C +P +N + + D VGSRI Y C GH L+G S C G WS PP C+
Sbjct: 1003 SCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQ 1062
Query: 408 YVNCGGLTPIEDGDVALIDNRTTH-GARALYSC------RENFTLVGNPERTC--GDE-- 456
+ CG I +GD + H G+ Y C R+ F LVG P C D+
Sbjct: 1063 RIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQV 1122
Query: 457 GIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGSL---ASYTCENGHILSGSTSVTCTL 513
GIW G AP+C+ PP V N + + SL + C+ G ++ G V C
Sbjct: 1123 GIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQA 1182
Query: 514 GGAWSGVPPSCKYVNCGTPTIHKGSFVLINGTT-TYGSIAQFTCEPDYWLNGAEELVCNR 572
W PSC V P I G + + G ++CEP Y L GA L C
Sbjct: 1183 LNKWEPELPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTP 1242
Query: 573 DGKWSYDIPSCELTSCPE--PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQ 630
G WS + P C + SC + ++P G + + + + ++F C+ G +L G C
Sbjct: 1243 QGDWSPEAPRCAVKSCDDFLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCVL 1302
Query: 631 DGE---WSGDSPTCEYIDCGKLPTLPYGT-MELLNGTTHLGSVIQYSCTTN------YRL 680
G W+ P CE+I C P + G +G G I Y+C + + L
Sbjct: 1303 VGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNL 1362
Query: 681 VGPVRRTCTEEFQ----WSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDN 736
+G CT + WS +PRCE ++ ++ T I +D
Sbjct: 1363 IGESTIRCTSDPHGNGVWSSPAPRCE--------LSVRAGHCKTPEQFPFASPTIPINDF 1414
Query: 737 RDVGNTYRIGALVKYRCEKGYKVIGESLS-TCEDNGQWSGTTPTCQYVDCGNPGRIENGK 795
+ +G + Y C GY G+ S +C +N WS C+ CG P NG
Sbjct: 1415 E-----FPVGTSLNYECRPGY--FGKMFSISCLENLVWSSVEDNCRRKSCGPPPEPFNGM 1467
Query: 796 VTLPSNATFYGATAFYQCDENWELEGVIRRMCQENG---TWSLEPPICKEITCPDPSAQI 852
V + ++ T +G+T Y C+E + L G C +G TW + PIC+ I+C +P I
Sbjct: 1468 VHINTD-TQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISC-EPPPTI 1525
Query: 853 KAGSGLLVVTSTLSIGGEAHYQCERG------YNLKGHQTRTCISK----GQWNGTVPVC 902
G ++ G YQC G + L G ++ C SK G W+ P C
Sbjct: 1526 SNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRC 1585
Query: 903 IPID-CRSPGNIENGKIVISNGSTL-FGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEP 960
I + C +P +EN V N S + + C + VG +C +GRW + P
Sbjct: 1586 ISTNKCTAP-EVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLP 1644
Query: 961 SC 962
C
Sbjct: 1645 HC 1646
Score = 224 bits (547), Expect = 2e-57
Identities = 175/645 (27%), Positives = 261/645 (40%), Gaps = 74/645 (11%)
Query: 368 DYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDN 427
++ +G+ + Y+C G+ S C K+ W+GA C+ +C +G V +I
Sbjct: 62 EFPIGTYLNYECRPGYSGR-PFSIICLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKG 120
Query: 428 RTTHGARALYSCRENFTLVGNPERTC---GDEGIWDGEAPRCLFDWCPDPPAVSNA---S 481
G++ YSC + + L+G+ TC GD IWD E P C C PP ++N S
Sbjct: 121 -IQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTITNGDFIS 179
Query: 482 VTVNGHKAGSLASYTCENG------HILSGSTSVTCTLG----GAWSGVPPSCKYVN-CG 530
GS+ +Y C G L G S+ CT G WSG P C N C
Sbjct: 180 TNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCT 239
Query: 531 TPTIHKGSFVLINGTT-TYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCP 589
P + G V N + + + +F C+P + + G + C KW ++PSC P
Sbjct: 240 PPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQP 299
Query: 590 EPEV--PSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCG 647
P+V + ++ + + CE G+ L G ++ C G+WS +PTCE C
Sbjct: 300 PPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCD 359
Query: 648 KLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCT---EEFQWSDSSPRCEEI 704
L LG+ + + C ++L G C E W+ S P CE+I
Sbjct: 360 DFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQI 419
Query: 705 RCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCE------KGYK 758
C P V N R G L + G V Y C+ +
Sbjct: 420 FCPSP--------PVIPNGRHTGKPL----------EVFPFGKTVNYTCDPHPDRGTSFD 461
Query: 759 VIGESLSTC----EDNGQWSGTTPTCQYV-DCGNPGRIENGKVTLPSNATFY--GATAFY 811
+IGES C + NG WS P C + C P K+ +NA+ + G + Y
Sbjct: 462 LIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKY 521
Query: 812 QCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEA 871
+C + C +N WS +CK +C P + +G++ V + + +G
Sbjct: 522 ECRPEY-YGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPV---NGMVHVITDIQVGSRI 577
Query: 872 HYQCERGYNLKGHQTRTCISKG---QWNGTVPVCIPIDCRSPGNIENGKIVISNGSTL-F 927
+Y C G+ L GH + CI G W+ P+C I C P I NG + +N +
Sbjct: 578 NYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHY 637
Query: 928 GSSVEYYC------LSQYQRVGPFLRKCL--DD--GRWSGEEPSC 962
GS V Y C ++ VG C DD G WSG P C
Sbjct: 638 GSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQC 682
Score = 221 bits (541), Expect = 8e-57
Identities = 188/665 (28%), Positives = 271/665 (40%), Gaps = 78/665 (11%)
Query: 352 TCGSPDKLLNTTI-LGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDG---FWSGAPPSCK 407
+C +P +N + + GS+I Y C +G+ L+G S C G W P C
Sbjct: 103 SCRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICD 162
Query: 408 YVNCGGLTPIEDGDVALIDNRTTH-GARALYSC------RENFTLVGNPERTC--GDE-- 456
+ CG I +GD + H G+ Y C R+ F LVG P C D+
Sbjct: 163 RIPCGLPPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQV 222
Query: 457 GIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGSL---ASYTCENGHILSGSTSVTCTL 513
GIW G AP+C+ PP V N + + SL + C+ G ++ G V C
Sbjct: 223 GIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQA 282
Query: 514 GGAWSGVPPSCKYVNCGTP--TIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCN 571
W PSC V C P +H + G ++CEP Y L GA + C
Sbjct: 283 LNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCT 341
Query: 572 RDGKWSYDIPSCELTSCPE--PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQ 629
G WS P+CE+ SC + ++ +G + + + + ++F C+ G +L G C
Sbjct: 342 PQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCV 401
Query: 630 QDGE---WSGDSPTCEYIDCGKLPTLPYG--TMELLNGTTHLGSVIQYSCT------TNY 678
G W+ P CE I C P +P G T + L G + Y+C T++
Sbjct: 402 LAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLE-VFPFGKTVNYTCDPHPDRGTSF 460
Query: 679 RLVGPVRRTCTEEFQ----WSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTS 734
L+G CT + Q WS +PRC + G+ ++ H L
Sbjct: 461 DLIGESTIRCTSDPQGNGVWSSPAPRC----------------GILGHCQAPDHFLFAKL 504
Query: 735 DNRDVGNTYRIGALVKYRCEKGYKVIGESLS-TCEDNGQWSGTTPTCQYVDCGNPGRIEN 793
+ + + IG +KY C Y G S TC DN WS C+ C P N
Sbjct: 505 KTQTNASDFPIGTSLKYECRPEY--YGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVN 562
Query: 794 GKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGT---WSLEPPICKEITCPDPSA 850
G V + ++ G+ Y C L G C +G WS +PPIC+ I C P
Sbjct: 563 GMVHVITDIQV-GSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPT 621
Query: 851 QIKAGSGLLVVTSTLSIGGEAHYQCERG------YNLKGHQTRTCISK----GQWNGTVP 900
I G + G Y+C G + L G + C S G W+G P
Sbjct: 622 -IANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAP 680
Query: 901 VC-IPIDCRSPGNIENGKIVISNGSTLFGSS--VEYYCLSQYQRVGPFLRKCLDDGRWSG 957
C IP C +P N+ENG I++S+ +LF + VE+ C + GP KC +W
Sbjct: 681 QCIIPNKC-TPPNVENG-ILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEP 738
Query: 958 EEPSC 962
E PSC
Sbjct: 739 ELPSC 743
Score = 205 bits (501), Expect = 6e-52
Identities = 178/668 (26%), Positives = 269/668 (40%), Gaps = 72/668 (10%)
Query: 353 CGSPDKLL----NTTILGNDYDVGSRIVYKC-PEGHMLLGDKSRHCKKDGFWSGAPPSCK 407
C +PD L T +D+ +G+ + Y+C PE + S C + WS CK
Sbjct: 943 CQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGR--PFSITCLDNLVWSSPKDVCK 1000
Query: 408 YVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTC---GDEGIWDGEAP 464
+C +G V +I + G+R YSC L+G+ C G+ W + P
Sbjct: 1001 RKSCKTPPDPVNGMVHVITDIQV-GSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPP 1059
Query: 465 RCLFDWCPDPPAVSNAS-VTVNGHKA--GSLASYTCENGHI------LSGSTSVTCTLG- 514
C C PP ++N ++ N GS+ +Y C G L G S+ CT
Sbjct: 1060 ICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSND 1119
Query: 515 ---GAWSGVPPSCKYVN-CGTPTIHKGSFVLINGTT-TYGSIAQFTCEPDYWLNGAEELV 569
G WSG P C N C P + G V N + + + +F C+P + + G +
Sbjct: 1120 DQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVK 1179
Query: 570 CNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAF--DYYVHSTINFHCEAGHKLIGEPNLV 627
C KW ++PSC P PE+ G + + ++ + + CE G+ L G +L
Sbjct: 1180 CQALNKWEPELPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLH 1239
Query: 628 CQQDGEWSGDSPTCEYIDCGK-LPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRR 686
C G+WS ++P C C L LP+G + L LG+ + + C +RL G
Sbjct: 1240 CTPQGDWSPEAPRCAVKSCDDFLGQLPHGRV-LFPLNLQLGAKVSFVCDEGFRLKGSSVS 1298
Query: 687 TCT---EEFQWSDSSPRCEEIRCSDP-IVAEKSIVSVTGNDRSHGHTLIRTSD-NRDVGN 741
C W++S P CE I C +P + D +G + T D + D G
Sbjct: 1299 HCVLVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGM 1358
Query: 742 TYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYV----DCGNPGRIENGKVT 797
T+ + RC S NG WS P C+ C P + T
Sbjct: 1359 TFNLIGESTIRCT----------SDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPT 1408
Query: 798 LPSNATFY--GATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAG 855
+P N + G + Y+C + + C EN WS C+ +C P
Sbjct: 1409 IPINDFEFPVGTSLNYECRPGY-FGKMFSISCLENLVWSSVEDNCRRKSCGPPPEPF--- 1464
Query: 856 SGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQ---WNGTVPVCIPIDCRSPGN 912
+G++ + + G +Y C G+ L G + TC+ G W+ P+C I C P
Sbjct: 1465 NGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPT 1524
Query: 913 IENGKIVISNGSTLF--GSSVEYYCLS------QYQRVGPFLRKCL--DD--GRWSGEEP 960
I NG SN T F G+ V Y C + ++ VG C DD G WS P
Sbjct: 1525 ISNGDF-YSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPP 1583
Query: 961 SCELATNE 968
C ++TN+
Sbjct: 1584 RC-ISTNK 1590
Score = 200 bits (488), Expect = 2e-50
Identities = 170/650 (26%), Positives = 256/650 (39%), Gaps = 79/650 (12%)
Query: 371 VGSRIVYKCPEGHMLLGDKSRHCKKDGF---WSGAPPSCKYVNCGGLTPIEDG-DVALID 426
+G+++ + C EG L G HC G W+ + P C+++ C I +G
Sbjct: 1278 LGAKVSFVCDEGFRLKGSSVSHCVLVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPS 1337
Query: 427 NRTTHGARALYSCREN------FTLVGNPERTCGDE----GIWDGEAPRCLFD----WCP 472
+G Y+C + F L+G C + G+W APRC C
Sbjct: 1338 GDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTSDPHGNGVWSSPAPRCELSVRAGHCK 1397
Query: 473 DPPAVSNASVTV--NGHK--AGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVN 528
P AS T+ N + G+ +Y C G+ S++C WS V +C+ +
Sbjct: 1398 TPEQFPFASPTIPINDFEFPVGTSLNYECRPGYF-GKMFSISCLENLVWSSVEDNCRRKS 1456
Query: 529 CGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGK---WSYDIPSCEL 585
CG P V IN T +GS ++C + L G+ C G W P CE+
Sbjct: 1457 CGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEI 1516
Query: 586 TSC-PEPEVPSGGYM--EAFDYYVHSTINFHCEAG------HKLIGEPNLVC----QQDG 632
SC P P + +G + ++ + + + C G +L+GE ++ C Q G
Sbjct: 1517 ISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVG 1576
Query: 633 EWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTH-LGSVIQYSCTTNYRLVGPVRRTCTEE 691
WS P C + P + N + L +I++ C + +VG C
Sbjct: 1577 VWSSPPPRCISTNKCTAPEVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTN 1636
Query: 692 FQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKY 751
+W P C + C P + HG + DN + G V Y
Sbjct: 1637 GRWGPKLPHCSRV-CQPP------------PEILHGEHTLSHQDN------FSPGQEVFY 1677
Query: 752 RCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGN-PGRIENGKVTLPSNATFYGATAF 810
CE Y + G + C G WS P C C + G++ +G+V LP N GA
Sbjct: 1678 SCEPSYDLRGAASLHCTPQGDWSPEAPRCTVKSCDDFLGQLPHGRVLLPLNLQL-GAKVS 1736
Query: 811 YQCDENWELEGVIRRMCQENG---TWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSI 867
+ CDE + L+G C G W+ P+C++I CP+P A I G +
Sbjct: 1737 FVCDEGFRLKGRSASHCVLAGMKALWNSSVPVCEQIFCPNPPA-ILNGRHTGTPFGDIPY 1795
Query: 868 GGEAHYQC----ERG--YNLKGHQTRTCIS----KGQWNGTVPVC---IPIDCRSPGNIE 914
G E Y C +RG +NL G + C S G W+ P C +P C P I+
Sbjct: 1796 GKEISYACDTHPDRGMTFNLIGESSIRCTSDPQGNGVWSSPAPRCELSVPAACPHPPKIQ 1855
Query: 915 NGKIVISNGST-LFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
NG + + S L G ++ Y C Y VG C D G WS + C+
Sbjct: 1856 NGHYIGGHVSLYLPGMTISYICDPGYLLVGKGFIFCTDQGIWSQLDHYCK 1905
Score = 197 bits (480), Expect = 2e-49
Identities = 174/678 (25%), Positives = 274/678 (40%), Gaps = 90/678 (13%)
Query: 345 ICQYLPPTCGSPDKLLNTTILGND---YDVGSRIVYKCPEGH------MLLGDKSRHCKK 395
IC +P CG P + N + + + GS + Y+C G L+G+ S +C
Sbjct: 160 ICDRIP--CGLPPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTS 217
Query: 396 D----GFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRTTHGARAL--YSCRENFTLVGNP 449
+ G WSG P C N +E+G + + DNR+ + + C+ F + G
Sbjct: 218 NDDQVGIWSGPAPQCIIPNKCTPPNVENG-ILVSDNRSLFSLNEVVEFRCQPGFVMKGPR 276
Query: 450 ERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTV---NGHKAGSLASYTCENGHILSGS 506
C W+ E P C C PP V +A T + G Y+CE G+ L G+
Sbjct: 277 RVKCQALNKWEPELPSCS-RVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGA 335
Query: 507 TSVTCTLGGAWSGVPPSCKYVNCGT--PTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNG 564
S+ CT G WS P+C+ +C + G VL G+ F C+ + L G
Sbjct: 336 ASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGR-VLFPVNLQLGAKVDFVCDEGFQLKG 394
Query: 565 AEELVC---NRDGKWSYDIPSCELTSCPEPEV-PSGGY----MEAFDYYVHSTINFHCE- 615
+ C + W+ +P CE CP P V P+G + +E F + T+N+ C+
Sbjct: 395 SSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPF--GKTVNYTCDP 452
Query: 616 -----AGHKLIGEPNLVCQQD----GEWSGDSPTCEYIDCGKLPT-LPYGTMELLNGTTH 665
LIGE + C D G WS +P C + + P + ++ +
Sbjct: 453 HPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASD 512
Query: 666 --LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGND 723
+G+ ++Y C Y P TC + WS C+ C P D
Sbjct: 513 FPIGTSLKYECRPEY-YGRPFSITCLDNLVWSSPKDVCKRKSCKTP------------PD 559
Query: 724 RSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTC 780
+G + T D+ ++G+ + Y C G+++IG S + C +G WS P C
Sbjct: 560 PVNGMVHVIT----DI----QVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPIC 611
Query: 781 QYVDCGNPGRIENGKVTLPSNATF-YGATAFYQCDEN------WELEGVIRRMCQEN--- 830
Q + CG P I NG + F YG+ Y+C+ +EL G C N
Sbjct: 612 QRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQ 671
Query: 831 -GTWSLEPPICKEITCPDPSAQIKAGSGLLVVT--STLSIGGEAHYQCERGYNLKGHQTR 887
G WS P C P+ +G+LV S S+ ++C+ G+ +KG +
Sbjct: 672 VGIWSGPAPQC---IIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRV 728
Query: 888 TCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLF-GSSVEYYCLSQYQRVGPFL 946
C + +W +P C + C+ P ++ + + + G V Y C Y G
Sbjct: 729 KCQALNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAAS 787
Query: 947 RKCLDDGRWSGEEPSCEL 964
+C G WS P+CE+
Sbjct: 788 MRCTPQGDWSPAAPTCEV 805
Score = 196 bits (479), Expect = 3e-49
Identities = 181/674 (26%), Positives = 263/674 (39%), Gaps = 82/674 (12%)
Query: 353 CGSPDKLLNTTILGNDYDV---GSRIVYKC---PE---GHMLLGDKSRHCKKD----GFW 399
C SP + N G +V G + Y C P+ L+G+ + C D G W
Sbjct: 871 CPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVW 930
Query: 400 SGAPPSCKYV-NCGGLTPIEDGDVALIDNRTTH--GARALYSCRENFTLVGNP-ERTCGD 455
S P C + +C + N + G Y CR + G P TC D
Sbjct: 931 SSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEY--YGRPFSITCLD 988
Query: 456 EGIWDGEAPRCLFDWCPDPPAVSNASV-TVNGHKAGSLASYTCENGHILSGSTSVTCTLG 514
+W C C PP N V + + GS +Y+C GH L G +S C L
Sbjct: 989 NLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILS 1048
Query: 515 GA---WSGVPPSCKYVNCGTP-TIHKGSFVLINGTTT-YGSIAQFTCEPD------YWLN 563
G WS PP C+ + CG P TI G F+ N YGS+ + C + L
Sbjct: 1049 GNTAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELV 1108
Query: 564 GAEELVC--NRD--GKWSYDIPSCELTS-CPEPEVPSGGYMEAFD--YYVHSTINFHCEA 616
G + C N D G WS P C + + C P V +G + + ++ + F C+
Sbjct: 1109 GEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQP 1168
Query: 617 GHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHL-GSVIQYSCT 675
G + G + CQ +W + P+C + C P + +G + G + YSC
Sbjct: 1169 GFVMKGPRRVKCQALNKWEPELPSCSRV-CQPPPEILHGEHTPSHQDNFSPGQEVFYSCE 1227
Query: 676 TNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSD 735
Y L G CT + WS +PRC C D + HG L +
Sbjct: 1228 PGYDLRGAASLHCTPQGDWSPEAPRCAVKSCDDFL-----------GQLPHGRVLFPLN- 1275
Query: 736 NRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTCQYVDCGNPGRIE 792
++GA V + C++G+++ G S+S C G W+ + P C+++ C NP I
Sbjct: 1276 -------LQLGAKVSFVCDEGFRLKGSSVSHCVLVGMRSLWNNSVPVCEHIFCPNPPAIL 1328
Query: 793 NGKVT-LPSNATFYGATAFYQCDEN------WELEGVIRRMCQE----NGTWSLEPPICK 841
NG+ T PS YG Y CD + + L G C NG WS P C+
Sbjct: 1329 NGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTSDPHGNGVWSSPAPRCE 1388
Query: 842 EIT----CPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNG 897
C P A + + +G +Y+C GY K +C+ W+
Sbjct: 1389 LSVRAGHCKTPEQFPFASPTIPINDFEFPVGTSLNYECRPGYFGKMFSI-SCLENLVWSS 1447
Query: 898 TVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGR--- 954
C C P NG + I N T FGS+V Y C ++ +G CL G
Sbjct: 1448 VEDNCRRKSCGPPPEPFNGMVHI-NTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVT 1506
Query: 955 WSGEEPSCELATNE 968
W + P CE+ + E
Sbjct: 1507 WDKKAPICEIISCE 1520
Score = 196 bits (477), Expect = 5e-49
Identities = 186/688 (27%), Positives = 271/688 (39%), Gaps = 83/688 (12%)
Query: 345 ICQYLPPTCGSPDKLLNTTILGN---DYDVGSRIVYKC---PEGHM---LLGDKSRHCKK 395
+C+++ C +P +LN G D G I Y C P+ M L+G+ + C
Sbjct: 1315 VCEHI--FCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTS 1372
Query: 396 D----GFWSGAPPSCKY-VNCGGLT-----PIEDGDVALIDNRTTHGARALYSCRENFTL 445
D G WS P C+ V G P + + D G Y CR +
Sbjct: 1373 DPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDFEFPVGTSLNYECRPGY-- 1430
Query: 446 VGNP-ERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGH-KAGSLASYTCENGHIL 503
G +C + +W C C PP N V +N + GS +Y+C G L
Sbjct: 1431 FGKMFSISCLENLVWSSVEDNCRRKSCGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRL 1490
Query: 504 SGSTSVTCTLGG---AWSGVPPSCKYVNCGTP-TIHKGSFVLINGTTTY-GSIAQFTCE- 557
GS S TC + G W P C+ ++C P TI G F N T+ + G++ + C
Sbjct: 1491 IGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHT 1550
Query: 558 -PD----YWLNGAEELVC-NRD---GKWSYDIPSCELTS-CPEPEVPSGGYMEAFDYYVH 607
PD + L G + C ++D G WS P C T+ C PEV + + +
Sbjct: 1551 GPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRCISTNKCTAPEVENAIRVPGNRSFFT 1610
Query: 608 ST--INFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTH 665
T I F C+ G ++G + CQ +G W P C + C P + +G L +
Sbjct: 1611 LTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHCSRV-CQPPPEILHGEHTLSHQDNF 1669
Query: 666 L-GSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDR 724
G + YSC +Y L G CT + WS +PRC C D +
Sbjct: 1670 SPGQEVFYSCEPSYDLRGAASLHCTPQGDWSPEAPRCTVKSCDDFL-----------GQL 1718
Query: 725 SHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTCQ 781
HG L+ + ++GA V + C++G+++ G S S C G W+ + P C+
Sbjct: 1719 PHGRVLLPLN--------LQLGAKVSFVCDEGFRLKGRSASHCVLAGMKALWNSSVPVCE 1770
Query: 782 YVDCGNPGRIENGKVT-LPSNATFYGATAFYQCDEN------WELEGVIRRMC----QEN 830
+ C NP I NG+ T P YG Y CD + + L G C Q N
Sbjct: 1771 QIFCPNPPAILNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGESSIRCTSDPQGN 1830
Query: 831 GTWSLEPPICK---EITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTR 887
G WS P C+ CP P +I+ G + S G Y C+ GY L G
Sbjct: 1831 GVWSSPAPRCELSVPAACPHPP-KIQNGHYIGGHVSLYLPGMTISYICDPGYLLVGKGFI 1889
Query: 888 TCISKGQWNGTVPVCIPIDCRSPGNIEN-GKIVISNGSTLFGSSVEYYCLSQYQRVGPFL 946
C +G W+ C ++C P + K + +G V C Y G
Sbjct: 1890 FCTDQGIWSQLDHYCKEVNCSFPLFMNGISKELEMKKVYHYGDYVTLKCEDGYTLEGSPW 1949
Query: 947 RKCLDDGRWSGEEPSCELATNEAVDSGT 974
+C D RW C T++A+ GT
Sbjct: 1950 SQCQADDRWDPPLAKCTSRTHDALIVGT 1977
Score = 188 bits (457), Expect = 1e-46
Identities = 173/666 (25%), Positives = 262/666 (39%), Gaps = 79/666 (11%)
Query: 353 CGSPDKLLNTTILGNDYDV---GSRIVYKC---PE---GHMLLGDKSRHCKKD----GFW 399
C SP + N G +V G + Y C P+ L+G+ + C D G W
Sbjct: 421 CPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVW 480
Query: 400 SGAPPSCKYV-NCGGLTPIEDGDVALIDNRTTH--GARALYSCRENFTLVGNP-ERTCGD 455
S P C + +C + N + G Y CR + G P TC D
Sbjct: 481 SSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEY--YGRPFSITCLD 538
Query: 456 EGIWDGEAPRCLFDWCPDPPAVSNASV-TVNGHKAGSLASYTCENGHILSGSTSVTCTLG 514
+W C C PP N V + + GS +Y+C GH L G +S C L
Sbjct: 539 NLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILS 598
Query: 515 GA---WSGVPPSCKYVNCGTP-TIHKGSFVLINGTTT-YGSIAQFTCEPD------YWLN 563
G WS PP C+ + CG P TI G F+ N YGS+ + C P + L
Sbjct: 599 GNAAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELV 658
Query: 564 GAEELVC--NRD--GKWSYDIPSCELTS-CPEPEVPSGGYMEAFD--YYVHSTINFHCEA 616
G + C N D G WS P C + + C P V +G + + ++ + F C+
Sbjct: 659 GEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQP 718
Query: 617 GHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHL-GSVIQYSCT 675
G + G + CQ +W + P+C + C P + + + G + YSC
Sbjct: 719 GFVMKGPRRVKCQALNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCE 777
Query: 676 TNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSD 735
Y L G CT + WS ++P CE C D + +G L +
Sbjct: 778 PGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDFM-----------GQLLNGRVLFPVN- 825
Query: 736 NRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTCQYVDCGNPGRIE 792
++GA V + C++G+++ G S S C G W+ + P C+ + C +P I
Sbjct: 826 -------LQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIP 878
Query: 793 NGKVT-LPSNATFYGATAFYQCD------ENWELEGVIRRMC----QENGTWSLEPPICK 841
NG+ T P +G Y CD +++L G C Q NG WS P C
Sbjct: 879 NGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCG 938
Query: 842 EI-TCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVP 900
+ C P + A S IG Y+C Y + TC+ W+
Sbjct: 939 ILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGRPFSI-TCLDNLVWSSPKD 997
Query: 901 VCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDG---RWSG 957
VC C++P + NG + + + GS + Y C + ++ +G +C+ G WS
Sbjct: 998 VCKRKSCKTPPDPVNGMVHVITDIQV-GSRINYSCTTGHRLIGHSSAECILSGNTAHWST 1056
Query: 958 EEPSCE 963
+ P C+
Sbjct: 1057 KPPICQ 1062
Score = 169 bits (411), Expect = 5e-41
Identities = 135/509 (26%), Positives = 209/509 (41%), Gaps = 59/509 (11%)
Query: 490 GSLASYTCENGHILSGST-SVTCTLGGAWSGVPPSCKYVNCGTPTIHKGSFVLINGTTTY 548
G+ +Y C G+ SG S+ C W+G C+ +C P V + +
Sbjct: 66 GTYLNYECRPGY--SGRPFSIICLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKGIQF 123
Query: 549 GSIAQFTCEPDYWLNGAEELVCNRDGK---WSYDIPSCELTSCP-EPEVPSGGYMEAF-- 602
GS +++C Y L G+ C G W + P C+ C P + +G ++
Sbjct: 124 GSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTITNGDFISTNRE 183
Query: 603 DYYVHSTINFHCEAGH------KLIGEPNLVC----QQDGEWSGDSPTCEYIDCGKLPTL 652
+++ S + + C G +L+GEP++ C Q G WSG +P C + P +
Sbjct: 184 NFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNV 243
Query: 653 PYGTMELLNGTTH-LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIV 711
G + N + L V+++ C + + GP R C +W P C + C P
Sbjct: 244 ENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRV-CQPP-- 300
Query: 712 AEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNG 771
D H R DN + G V Y CE GY + G + C G
Sbjct: 301 ----------PDVLHAERTQRDKDN------FSPGQEVFYSCEPGYDLRGAASMRCTPQG 344
Query: 772 QWSGTTPTCQYVDCGN-PGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQEN 830
WS PTC+ C + G++ NG+V P N GA + CDE ++L+G C
Sbjct: 345 DWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQL-GAKVDFVCDEGFQLKGSSASYCVLA 403
Query: 831 GT---WSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCE----RG--YNL 881
G W+ P+C++I CP P I G G +Y C+ RG ++L
Sbjct: 404 GMESLWNSSVPVCEQIFCPSPPV-IPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDL 462
Query: 882 KGHQTRTCIS----KGQWNGTVPVC-IPIDCRSPGNIENGKIVISNGSTLF--GSSVEYY 934
G T C S G W+ P C I C++P + K+ ++ F G+S++Y
Sbjct: 463 IGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYE 522
Query: 935 CLSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
C +Y PF CLD+ WS + C+
Sbjct: 523 CRPEYYG-RPFSITCLDNLVWSSPKDVCK 550
Score = 101 bits (243), Expect = 1e-20
Identities = 80/316 (25%), Positives = 124/316 (39%), Gaps = 42/316 (13%)
Query: 666 LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRS 725
+G+ + Y C Y P C + W+ + RC C +P +V V
Sbjct: 65 IGTYLNYECRPGYS-GRPFSIICLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKG--- 120
Query: 726 HGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTCQY 782
+ G+ +KY C KGY++IG S +TC +G W TP C
Sbjct: 121 -----------------IQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDR 163
Query: 783 VDCGNPGRIENGKVTLPSNATF-YGATAFYQCDEN------WELEGVIRRMCQEN----G 831
+ CG P I NG + F YG+ Y+C+ +EL G C N G
Sbjct: 164 IPCGLPPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVG 223
Query: 832 TWSLEPPICKEITCPDPSAQIKAGSGLLVV--TSTLSIGGEAHYQCERGYNLKGHQTRTC 889
WS P C P+ +G+LV S S+ ++C+ G+ +KG + C
Sbjct: 224 IWSGPAPQC---IIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKC 280
Query: 890 ISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLF-GSSVEYYCLSQYQRVGPFLRK 948
+ +W +P C + C+ P ++ + + + G V Y C Y G +
Sbjct: 281 QALNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMR 339
Query: 949 CLDDGRWSGEEPSCEL 964
C G WS P+CE+
Sbjct: 340 CTPQGDWSPAAPTCEV 355
Score = 44.0 bits (99), Expect = 0.003
Identities = 17/42 (40%), Positives = 24/42 (57%)
Query: 17 NEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
+++N G Y C+ GY+L GA CT +GDW+ E P C
Sbjct: 1212 HQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGDWSPEAPRC 1253
Score = 42.7 bits (96), Expect = 0.007
Identities = 18/57 (31%), Positives = 28/57 (49%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C P + ++ +++N G Y C+ Y+L GA CT +GDW+ E P C
Sbjct: 1650 CQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCTPQGDWSPEAPRC 1706
Score = 42.3 bits (95), Expect = 0.009
Identities = 19/57 (33%), Positives = 28/57 (49%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C P +A + +++N G Y C+ GY+L GA CT +GDW+ P C
Sbjct: 297 CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTC 353
Score = 42.3 bits (95), Expect = 0.009
Identities = 19/57 (33%), Positives = 28/57 (49%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C P +A + +++N G Y C+ GY+L GA CT +GDW+ P C
Sbjct: 747 CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTC 803
Score = 37.5 bits (83), Expect = 0.26
Identities = 20/60 (33%), Positives = 27/60 (45%), Gaps = 5/60 (8%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGD---WTLEPPFC 58
C +P P N V + + I G+ Y C +GY L G+ C + GD W E P C
Sbjct: 104 CRNPPDPVNGMVHVI--KGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPIC 161
Score = 37.5 bits (83), Expect = 0.26
Identities = 20/60 (33%), Positives = 27/60 (45%), Gaps = 5/60 (8%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGD---WTLEPPFC 58
C P P N V + + I G+ Y C G+ L G EC L G+ W+ +PP C
Sbjct: 554 CKTPPDPVNGMVHVITD--IQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPIC 611
Score = 37.5 bits (83), Expect = 0.26
Identities = 20/60 (33%), Positives = 27/60 (45%), Gaps = 5/60 (8%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGD---WTLEPPFC 58
C P P N V + + I G+ Y C G+ L G EC L G+ W+ +PP C
Sbjct: 1004 CKTPPDPVNGMVHVITD--IQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPIC 1061
Score = 37.5 bits (83), Expect = 0.26
Identities = 19/60 (31%), Positives = 27/60 (45%), Gaps = 5/60 (8%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGD---WTLEPPFC 58
CG P P N V I + G+ Y C+EG+ L G+ C + G+ W + P C
Sbjct: 1457 CGPPPEPFNGMVHINTDTQF--GSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPIC 1514
>BC028067-1|AAH28067.2| 789|Homo sapiens SELP protein protein.
Length = 789
Score = 234 bits (572), Expect = 1e-60
Identities = 193/764 (25%), Positives = 312/764 (40%), Gaps = 89/764 (11%)
Query: 236 SFDEARKQCQSHGGDLIHGFQGATSSFLTQELERRKAQLKTQLVWIGAQKEPGLTSRTWQ 295
S++ +RK CQ+ DL+ +L + L + WIG +K ++TW
Sbjct: 51 SWNISRKYCQNRYTDLVAIQNKNEIDYLNKVLP-----YYSSYYWIGIRKN----NKTWT 101
Query: 296 WVDGELV---SKPSWGKDQPNNYNGEQNCV---VLDGGRGWLWNDVGCNLDYLHWICQYL 349
WV + +W ++PNN ++CV + WND C L H +C
Sbjct: 102 WVGTKKALTNEAENWADNEPNNKRNNEDCVEIYIKSPSAPGKWNDEHC-LKKKHALCY-- 158
Query: 350 PPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYV 409
T D ++ + G +C E +G+ + C GF+ P C+YV
Sbjct: 159 --TASCQD--MSCSKQG-----------ECLE---TIGNYTCSCYP-GFYG---PECEYV 196
Query: 410 N-CGGLTPIEDGDVALID--NRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRC 466
CG L + + + ++ + C + + + G + C GIW + P+C
Sbjct: 197 RECGELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQC 256
Query: 467 LFDWCPDPPAVSNASVT-VNGHKA---GSLASYTCENGHILSGSTSVTCTLGGAWSGVPP 522
L CP ++T ++ KA S S++CE G L G V CT G W+ P
Sbjct: 257 LAAQCPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASGVWTAPAP 316
Query: 523 SCKYVNCG-TPTIHKGSFVLINGTTT--YGSIAQFTCEPDYWLNGAEELVCNRDGKWSYD 579
CK V C ++G+ ++ T YGS +F C+P Y + G + L C G WS
Sbjct: 317 VCKAVQCQHLEAPNEGTMDCVHPLTAFAYGSSCKFECQPGYRVRGLDMLRCIDSGHWSAP 376
Query: 580 IPSCELTSCPEPEVPSGGYME------AFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGE 633
+P+CE SC E P G M+ AF Y + +F C G L G + C G+
Sbjct: 377 LPTCEAISCEPLESPVHGSMDCSPSLRAFQY--DTNCSFRCAEGFMLRGADIVRCDNLGQ 434
Query: 634 WSGDSPTCEYIDCGKLPTLPYGTMELLN--GTTHLGSVIQYSCTTNYRLVGPVRRTCTEE 691
W+ +P C+ + C LP + + G SV ++C LVG C
Sbjct: 435 WTAPAPVCQALQCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLAT 494
Query: 692 FQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKY 751
W+ P C+ I C+ P+++ ++ T ++ + +T ++
Sbjct: 495 GNWNSVPPECQAIPCT-PLLSPQNGTM----------TCVQPLGSSSYKST------CQF 537
Query: 752 RCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFY--GATA 809
C++GY + G C +G+W+ + P C+ + C E G + + G+T
Sbjct: 538 ICDEGYSLSGPERLDCTRSGRWTDSPPMCEAIKCPELFAPEQGSLDCSDTRGEFNVGSTC 597
Query: 810 FYQCDENWELEGVIRRMCQENGTWSLEPPICKEI-TCPDPSAQIKA----GSGLLVVT-- 862
+ C+ ++LEG C +G WS PP CK I + P P Q A G G +
Sbjct: 598 HFSCNNGFKLEGPNNVECTTSGRWSATPPTCKGIASLPTPGVQCPALTTPGQGTMYCRHH 657
Query: 863 -STLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVIS 921
T ++ C G+ L G T +C GQW P C + C + + S
Sbjct: 658 PGTFGFNTTCYFGCNAGFTLIGDSTLSCRPSGQWTAVTPACRAVKCSELHVNKPIAMNCS 717
Query: 922 N--GSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
N G+ +GS ++CL G C ++G WS P+C+
Sbjct: 718 NLWGNFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTCQ 761
Score = 196 bits (479), Expect = 3e-49
Identities = 131/489 (26%), Positives = 197/489 (40%), Gaps = 29/489 (5%)
Query: 377 YKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRTT--HGAR 434
+ C EG L+G + C G W+ P CK V C L +G + + T +G+
Sbjct: 289 FSCEEGFALVGPEVVQCTASGVWTAPAPVCKAVQCQHLEAPNEGTMDCVHPLTAFAYGSS 348
Query: 435 ALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCP--DPPAVSN--ASVTVNGHKAG 490
+ C+ + + G C D G W P C C + P + S ++ +
Sbjct: 349 CKFECQPGYRVRGLDMLRCIDSGHWSAPLPTCEAISCEPLESPVHGSMDCSPSLRAFQYD 408
Query: 491 SLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTIHKGSFVLIN---GTTT 547
+ S+ C G +L G+ V C G W+ P C+ + C + + V + G
Sbjct: 409 TNCSFRCAEGFMLRGADIVRCDNLGQWTAPAPVCQALQCQDLPVPNEARVNCSHPFGAFR 468
Query: 548 YGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFDYY-- 605
Y S+ FTC L GA L C G W+ P C+ C P G M
Sbjct: 469 YQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPECQAIPCTPLLSPQNGTMTCVQPLGS 528
Query: 606 --VHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLN-- 661
ST F C+ G+ L G L C + G W+ P CE I C +L G+++ +
Sbjct: 529 SSYKSTCQFICDEGYSLSGPERLDCTRSGRWTDSPPMCEAIKCPELFAPEQGSLDCSDTR 588
Query: 662 GTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTG 721
G ++GS +SC ++L GP CT +WS + P C+ I + ++ G
Sbjct: 589 GEFNVGSTCHFSCNNGFKLEGPNNVECTTSGRWSATPPTCKGIASLPTPGVQCPALTTPG 648
Query: 722 NDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQ 781
T R T+ + C G+ +IG+S +C +GQW+ TP C+
Sbjct: 649 QG---------TMYCRHHPGTFGFNTTCYFGCNAGFTLIGDSTLSCRPSGQWTAVTPACR 699
Query: 782 YVDCGNPGRIENGKVTLPSN--ATF-YGATAFYQCDENWELEGVIRRMCQENGTWSLEPP 838
V C + SN F YG+ + C E L G + CQENG WS P
Sbjct: 700 AVKCSEL-HVNKPIAMNCSNLWGNFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVP 758
Query: 839 ICKEI-TCP 846
C++ CP
Sbjct: 759 TCQDDGKCP 767
Score = 136 bits (329), Expect = 4e-31
Identities = 84/299 (28%), Positives = 127/299 (42%), Gaps = 23/299 (7%)
Query: 377 YKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALID--NRTTHGAR 434
+ C EG +L+G C G W+ PP C+ + C L ++G + + +++ +
Sbjct: 475 FTCNEGLLLVGASVLQCLATGNWNSVPPECQAIPCTPLLSPQNGTMTCVQPLGSSSYKST 534
Query: 435 ALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASV----TVNGHKAG 490
+ C E ++L G C G W P C CP+ A S+ T G
Sbjct: 535 CQFICDEGYSLSGPERLDCTRSGRWTDSPPMCEAIKCPELFAPEQGSLDCSDTRGEFNVG 594
Query: 491 SLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYV-NCGTPTIH--------KGSFVL 541
S ++C NG L G +V CT G WS PP+CK + + TP + +G+
Sbjct: 595 STCHFSCNNGFKLEGPNNVECTTSGRWSATPPTCKGIASLPTPGVQCPALTTPGQGTMYC 654
Query: 542 IN--GTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYM 599
+ GT + + F C + L G L C G+W+ P+C C E V M
Sbjct: 655 RHHPGTFGFNTTCYFGCNAGFTLIGDSTLSCRPSGQWTAVTPACRAVKCSELHVNKPIAM 714
Query: 600 EAFDYYVH----STINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPY 654
+ + + S +FHC G L G CQ++G WS PTC+ D GK P P+
Sbjct: 715 NCSNLWGNFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTCQ--DDGKCPLNPH 771
Score = 110 bits (265), Expect = 2e-23
Identities = 79/275 (28%), Positives = 114/275 (41%), Gaps = 23/275 (8%)
Query: 346 CQYLPPT-CGSPDKLLNTTI--LGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGA 402
CQ +P T SP T + LG+ S + C EG+ L G + C + G W+ +
Sbjct: 504 CQAIPCTPLLSPQNGTMTCVQPLGSS-SYKSTCQFICDEGYSLSGPERLDCTRSGRWTDS 562
Query: 403 PPSCKYVNCGGLTPIEDGDVALIDNRTTH--GARALYSCRENFTLVGNPERTCGDEGIWD 460
PP C+ + C L E G + D R G+ +SC F L G C G W
Sbjct: 563 PPMCEAIKCPELFAPEQGSLDCSDTRGEFNVGSTCHFSCNNGFKLEGPNNVECTTSGRWS 622
Query: 461 GEAPRCLFDWCPDPPAVSNASVTVNG-------HKAGSLASYT-----CENGHILSGSTS 508
P C P V ++T G H G+ T C G L G ++
Sbjct: 623 ATPPTCKGIASLPTPGVQCPALTTPGQGTMYCRHHPGTFGFNTTCYFGCNAGFTLIGDST 682
Query: 509 VTCTLGGAWSGVPPSCKYVNCGTPTIHKGSFVLIN---GTTTYGSIAQFTCEPDYWLNGA 565
++C G W+ V P+C+ V C ++K + + G +YGSI F C LNG+
Sbjct: 683 LSCRPSGQWTAVTPACRAVKCSELHVNKPIAMNCSNLWGNFSYGSICSFHCLEGQLLNGS 742
Query: 566 EELVCNRDGKWSYDIPSCELT-SCP-EPEVPSGGY 598
+ C +G WS +P+C+ CP P G Y
Sbjct: 743 AQTACQENGHWSTTVPTCQDDGKCPLNPHSHLGTY 777
Score = 89.8 bits (213), Expect = 5e-17
Identities = 52/201 (25%), Positives = 85/201 (42%), Gaps = 7/201 (3%)
Query: 778 PTCQYV-DCGN---PGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTW 833
P C+YV +CG P + N +F +F+ C + +++ G + C +G W
Sbjct: 191 PECEYVRECGELELPQHVLMNCSHPLGNFSFNSQCSFH-CTDGYQVNGPSKLECLASGIW 249
Query: 834 SLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKG 893
+ +PP C CP + L + CE G+ L G + C + G
Sbjct: 250 TNKPPQCLAAQCPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASG 309
Query: 894 QWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLF--GSSVEYYCLSQYQRVGPFLRKCLD 951
W PVC + C+ G + + T F GSS ++ C Y+ G + +C+D
Sbjct: 310 VWTAPAPVCKAVQCQHLEAPNEGTMDCVHPLTAFAYGSSCKFECQPGYRVRGLDMLRCID 369
Query: 952 DGRWSGEEPSCELATNEAVDS 972
G WS P+CE + E ++S
Sbjct: 370 SGHWSAPLPTCEAISCEPLES 390
Score = 40.7 bits (91), Expect = 0.028
Identities = 15/28 (53%), Positives = 17/28 (60%)
Query: 31 CDEGYELFGARQRECTLRGDWTLEPPFC 58
CDEGY L G + +CT G WT PP C
Sbjct: 539 CDEGYSLSGPERLDCTRSGRWTDSPPMC 566
Score = 36.7 bits (81), Expect = 0.45
Identities = 13/35 (37%), Positives = 19/35 (54%)
Query: 24 GTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
G+ + C+ G++L G ECT G W+ PP C
Sbjct: 594 GSTCHFSCNNGFKLEGPNNVECTTSGRWSATPPTC 628
Score = 35.9 bits (79), Expect = 0.79
Identities = 16/58 (27%), Positives = 28/58 (48%), Gaps = 1/58 (1%)
Query: 2 CGHPAVPPNARVSIPNE-ENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
CG +P + ++ + N + + C +GY++ G + EC G WT +PP C
Sbjct: 199 CGELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQC 256
Score = 34.7 bits (76), Expect = 1.8
Identities = 18/59 (30%), Positives = 27/59 (45%), Gaps = 1/59 (1%)
Query: 1 RCGHPAVPPNARVSIPNEENIVA-GTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
+C VP ARV+ + ++ + C+EG L GA +C G+W PP C
Sbjct: 446 QCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPEC 504
Score = 34.3 bits (75), Expect = 2.4
Identities = 12/30 (40%), Positives = 16/30 (53%)
Query: 29 YECDEGYELFGARQRECTLRGDWTLEPPFC 58
+ C+EG+ L G +CT G WT P C
Sbjct: 289 FSCEEGFALVGPEVVQCTASGVWTAPAPVC 318
>AF542391-1|AAN06828.1| 830|Homo sapiens selectin P (granule
membrane protein 140kDa, antigen CD62) protein.
Length = 830
Score = 233 bits (570), Expect = 3e-60
Identities = 193/764 (25%), Positives = 311/764 (40%), Gaps = 89/764 (11%)
Query: 236 SFDEARKQCQSHGGDLIHGFQGATSSFLTQELERRKAQLKTQLVWIGAQKEPGLTSRTWQ 295
S++ +RK CQ+ DL+ +L + L + WIG +K ++TW
Sbjct: 52 SWNISRKYCQNRYTDLVAIQNKNEIDYLNKVLP-----YYSSYYWIGIRKN----NKTWT 102
Query: 296 WVDGELV---SKPSWGKDQPNNYNGEQNCV---VLDGGRGWLWNDVGCNLDYLHWICQYL 349
WV + +W ++PNN ++CV + WND C L H +C
Sbjct: 103 WVGTKKALTNEAENWADNEPNNKRNNEDCVEIYIKSPSAPGKWNDEHC-LKKKHALCY-- 159
Query: 350 PPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYV 409
T D ++ + G +C E +G+ + C GF+ P C+YV
Sbjct: 160 --TASCQD--MSCSKQG-----------ECLE---TIGNYTCSCYP-GFYG---PECEYV 197
Query: 410 N-CGGLTPIEDGDVALID--NRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRC 466
CG L + + + ++ + C + + + G + C GIW + P+C
Sbjct: 198 RECGELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQC 257
Query: 467 LFDWCPDPPAVSNASVT-VNGHKA---GSLASYTCENGHILSGSTSVTCTLGGAWSGVPP 522
L CP ++T ++ KA S S++CE G L G V CT G W+ P
Sbjct: 258 LAAQCPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASGVWTAPAP 317
Query: 523 SCKYVNCG-TPTIHKGSFVLINGTTT--YGSIAQFTCEPDYWLNGAEELVCNRDGKWSYD 579
CK V C +G+ ++ T YGS +F C+P Y + G + L C G WS
Sbjct: 318 VCKAVQCQHLEAPSEGTMDCVHPLTAFAYGSSCKFECQPGYRVRGLDMLRCIDSGHWSAP 377
Query: 580 IPSCELTSCPEPEVPSGGYME------AFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGE 633
+P+CE SC E P G M+ AF Y + +F C G L G + C G+
Sbjct: 378 LPTCEAISCEPLESPVHGSMDCSPSLRAFQY--DTNCSFRCAEGFMLRGADIVRCDNLGQ 435
Query: 634 WSGDSPTCEYIDCGKLPTLPYGTMELLN--GTTHLGSVIQYSCTTNYRLVGPVRRTCTEE 691
W+ +P C+ + C LP + + G SV ++C LVG C
Sbjct: 436 WTAPAPVCQALQCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLAT 495
Query: 692 FQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKY 751
W+ P C+ I C+ P+++ ++ T ++ + +T ++
Sbjct: 496 GNWNSVPPECQAIPCT-PLLSPQNGTM----------TCVQPLGSSSYKST------CQF 538
Query: 752 RCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFY--GATA 809
C++GY + G C +G+W+ + P C+ + C E G + + G+T
Sbjct: 539 ICDEGYSLSGPERLDCTRSGRWTDSPPMCEAIKCPELFAPEQGSLDCSDTRGEFNVGSTC 598
Query: 810 FYQCDENWELEGVIRRMCQENGTWSLEPPICKEI-TCPDPSAQIKA----GSGLLVVT-- 862
+ C+ ++LEG C +G WS PP CK I + P P Q A G G +
Sbjct: 599 HFSCNNGFKLEGPNNVECTTSGRWSATPPTCKGIASLPTPGVQCPALTTPGQGTMYCRHH 658
Query: 863 -STLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVIS 921
T ++ C G+ L G T +C GQW P C + C + + S
Sbjct: 659 PGTFGFNTTCYFGCNAGFTLIGDSTLSCRPSGQWTAVTPACRAVKCSELHVNKPIAMNCS 718
Query: 922 N--GSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
N G+ +GS ++CL G C ++G WS P+C+
Sbjct: 719 NLWGNFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTCQ 762
Score = 89.8 bits (213), Expect = 5e-17
Identities = 52/201 (25%), Positives = 85/201 (42%), Gaps = 7/201 (3%)
Query: 778 PTCQYV-DCGN---PGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTW 833
P C+YV +CG P + N +F +F+ C + +++ G + C +G W
Sbjct: 192 PECEYVRECGELELPQHVLMNCSHPLGNFSFNSQCSFH-CTDGYQVNGPSKLECLASGIW 250
Query: 834 SLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKG 893
+ +PP C CP + L + CE G+ L G + C + G
Sbjct: 251 TNKPPQCLAAQCPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASG 310
Query: 894 QWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLF--GSSVEYYCLSQYQRVGPFLRKCLD 951
W PVC + C+ G + + T F GSS ++ C Y+ G + +C+D
Sbjct: 311 VWTAPAPVCKAVQCQHLEAPSEGTMDCVHPLTAFAYGSSCKFECQPGYRVRGLDMLRCID 370
Query: 952 DGRWSGEEPSCELATNEAVDS 972
G WS P+CE + E ++S
Sbjct: 371 SGHWSAPLPTCEAISCEPLES 391
Score = 40.7 bits (91), Expect = 0.028
Identities = 15/28 (53%), Positives = 17/28 (60%)
Query: 31 CDEGYELFGARQRECTLRGDWTLEPPFC 58
CDEGY L G + +CT G WT PP C
Sbjct: 540 CDEGYSLSGPERLDCTRSGRWTDSPPMC 567
Score = 36.7 bits (81), Expect = 0.45
Identities = 13/35 (37%), Positives = 19/35 (54%)
Query: 24 GTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
G+ + C+ G++L G ECT G W+ PP C
Sbjct: 595 GSTCHFSCNNGFKLEGPNNVECTTSGRWSATPPTC 629
Score = 35.9 bits (79), Expect = 0.79
Identities = 16/58 (27%), Positives = 28/58 (48%), Gaps = 1/58 (1%)
Query: 2 CGHPAVPPNARVSIPNE-ENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
CG +P + ++ + N + + C +GY++ G + EC G WT +PP C
Sbjct: 200 CGELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQC 257
Score = 34.7 bits (76), Expect = 1.8
Identities = 18/59 (30%), Positives = 27/59 (45%), Gaps = 1/59 (1%)
Query: 1 RCGHPAVPPNARVSIPNEENIVA-GTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
+C VP ARV+ + ++ + C+EG L GA +C G+W PP C
Sbjct: 447 QCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPEC 505
Score = 34.3 bits (75), Expect = 2.4
Identities = 12/30 (40%), Positives = 16/30 (53%)
Query: 29 YECDEGYELFGARQRECTLRGDWTLEPPFC 58
+ C+EG+ L G +CT G WT P C
Sbjct: 290 FSCEEGFALVGPEVVQCTASGVWTAPAPVC 319
Score = 32.3 bits (70), Expect = 9.7
Identities = 20/62 (32%), Positives = 27/62 (43%), Gaps = 3/62 (4%)
Query: 20 NIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTNVAFRKPANQSTTVRGGAA 79
N G+I + C EG L G+ Q C G W+ P C A ++ T GGA
Sbjct: 723 NFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTC---QAGPLTIQEALTYFGGAV 779
Query: 80 AN 81
A+
Sbjct: 780 AS 781
>M60234-1|AAA35910.1| 830|Homo sapiens granule membrane protein-140
protein.
Length = 830
Score = 231 bits (565), Expect = 1e-59
Identities = 192/764 (25%), Positives = 310/764 (40%), Gaps = 89/764 (11%)
Query: 236 SFDEARKQCQSHGGDLIHGFQGATSSFLTQELERRKAQLKTQLVWIGAQKEPGLTSRTWQ 295
S++ +RK CQ+ DL+ +L + L + WIG +K ++TW
Sbjct: 52 SWNISRKYCQNRYTDLVAIQNKNEIDYLNKVLP-----YYSSYYWIGIRKN----NKTWT 102
Query: 296 WVDGELV---SKPSWGKDQPNNYNGEQNCV---VLDGGRGWLWNDVGCNLDYLHWICQYL 349
WV + +W ++PNN ++CV + WND C L H +C
Sbjct: 103 WVGTKKALTNEAENWADNEPNNKRNNEDCVEIYIKSPSAPGKWNDEHC-LKKKHALCY-- 159
Query: 350 PPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYV 409
T D ++ + G +C E +G+ + C GF+ P C+YV
Sbjct: 160 --TASCQD--MSCSKQG-----------ECLE---TIGNYTCSCYP-GFYG---PECEYV 197
Query: 410 N-CGGLTPIEDGDVALID--NRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRC 466
CG L + + + ++ + C + + + G + C GIW + P+C
Sbjct: 198 RECGELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQC 257
Query: 467 LFDWCPDPPAVSNAS-VTVNGHKA---GSLASYTCENGHILSGSTSVTCTLGGAWSGVPP 522
L CP + + ++ KA S S++CE G L G V CT G W+ P
Sbjct: 258 LAAQCPPLKIPERGNMICLHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASGVWTAPAP 317
Query: 523 SCKYVNCG-TPTIHKGSFVLINGTTT--YGSIAQFTCEPDYWLNGAEELVCNRDGKWSYD 579
CK V C +G+ ++ T YGS +F C+P Y + G + L C G WS
Sbjct: 318 VCKAVQCQHLEAPSEGTMDCVHPLTAFAYGSSCKFECQPGYRVRGLDMLRCIDSGHWSAP 377
Query: 580 IPSCELTSCPEPEVPSGGYME------AFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGE 633
+P+CE SC E P G M+ AF Y + +F C G L G + C G+
Sbjct: 378 LPTCEAISCEPLESPVHGSMDCSPSLRAFQY--DTNCSFRCAEGFMLRGADIVRCDNLGQ 435
Query: 634 WSGDSPTCEYIDCGKLPTLPYGTMELLN--GTTHLGSVIQYSCTTNYRLVGPVRRTCTEE 691
W+ +P C+ + C LP + + G SV ++C LVG C
Sbjct: 436 WTAPAPVCQALQCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLAT 495
Query: 692 FQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKY 751
W+ P C+ I C+ P+++ ++ T ++ + +T ++
Sbjct: 496 GNWNSVPPECQAIPCT-PLLSPQNGTM----------TCVQPLGSSSYKST------CQF 538
Query: 752 RCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFY--GATA 809
C++GY + G C +G+W+ + P C+ + C E G + + G+T
Sbjct: 539 ICDEGYSLSGPERLDCTRSGRWTDSPPMCEAIKCPELFAPEQGSLDCSDTRGEFNVGSTC 598
Query: 810 FYQCDENWELEGVIRRMCQENGTWSLEPPICKEI-TCPDPSAQIKA----GSGLLVVT-- 862
+ C+ ++LEG C +G WS PP CK I + P P Q A G G +
Sbjct: 599 HFSCNNGFKLEGPNNVECTTSGRWSATPPTCKGIASLPTPGLQCPALTTPGQGTMYCRHH 658
Query: 863 -STLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVIS 921
T ++ C G+ L G T +C GQW P C + C + + S
Sbjct: 659 PGTFGFNTTCYFGCNAGFTLIGDSTLSCRPSGQWTAVTPACRAVKCSELHVNKPIAMNCS 718
Query: 922 N--GSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
N G+ +GS ++CL G C ++G WS P+C+
Sbjct: 719 NLWGNFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTCQ 762
Score = 89.0 bits (211), Expect = 8e-17
Identities = 52/201 (25%), Positives = 85/201 (42%), Gaps = 7/201 (3%)
Query: 778 PTCQYV-DCGN---PGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTW 833
P C+YV +CG P + N +F +F+ C + +++ G + C +G W
Sbjct: 192 PECEYVRECGELELPQHVLMNCSHPLGNFSFNSQCSFH-CTDGYQVNGPSKLECLASGIW 250
Query: 834 SLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKG 893
+ +PP C CP + L + CE G+ L G + C + G
Sbjct: 251 TNKPPQCLAAQCPPLKIPERGNMICLHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASG 310
Query: 894 QWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLF--GSSVEYYCLSQYQRVGPFLRKCLD 951
W PVC + C+ G + + T F GSS ++ C Y+ G + +C+D
Sbjct: 311 VWTAPAPVCKAVQCQHLEAPSEGTMDCVHPLTAFAYGSSCKFECQPGYRVRGLDMLRCID 370
Query: 952 DGRWSGEEPSCELATNEAVDS 972
G WS P+CE + E ++S
Sbjct: 371 SGHWSAPLPTCEAISCEPLES 391
Score = 40.7 bits (91), Expect = 0.028
Identities = 15/28 (53%), Positives = 17/28 (60%)
Query: 31 CDEGYELFGARQRECTLRGDWTLEPPFC 58
CDEGY L G + +CT G WT PP C
Sbjct: 540 CDEGYSLSGPERLDCTRSGRWTDSPPMC 567
Score = 36.7 bits (81), Expect = 0.45
Identities = 13/35 (37%), Positives = 19/35 (54%)
Query: 24 GTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
G+ + C+ G++L G ECT G W+ PP C
Sbjct: 595 GSTCHFSCNNGFKLEGPNNVECTTSGRWSATPPTC 629
Score = 35.9 bits (79), Expect = 0.79
Identities = 16/58 (27%), Positives = 28/58 (48%), Gaps = 1/58 (1%)
Query: 2 CGHPAVPPNARVSIPNE-ENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
CG +P + ++ + N + + C +GY++ G + EC G WT +PP C
Sbjct: 200 CGELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQC 257
Score = 34.7 bits (76), Expect = 1.8
Identities = 18/59 (30%), Positives = 27/59 (45%), Gaps = 1/59 (1%)
Query: 1 RCGHPAVPPNARVSIPNEENIVA-GTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
+C VP ARV+ + ++ + C+EG L GA +C G+W PP C
Sbjct: 447 QCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPEC 505
Score = 34.3 bits (75), Expect = 2.4
Identities = 12/30 (40%), Positives = 16/30 (53%)
Query: 29 YECDEGYELFGARQRECTLRGDWTLEPPFC 58
+ C+EG+ L G +CT G WT P C
Sbjct: 290 FSCEEGFALVGPEVVQCTASGVWTAPAPVC 319
Score = 32.3 bits (70), Expect = 9.7
Identities = 20/62 (32%), Positives = 27/62 (43%), Gaps = 3/62 (4%)
Query: 20 NIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTNVAFRKPANQSTTVRGGAA 79
N G+I + C EG L G+ Q C G W+ P C A ++ T GGA
Sbjct: 723 NFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTC---QAGPLTIQEALTYFGGAV 779
Query: 80 AN 81
A+
Sbjct: 780 AS 781
>M25322-1|AAA35911.1| 830|Homo sapiens protein ( Human granule
membrane protein-140 mRNA, complete cds. ).
Length = 830
Score = 231 bits (565), Expect = 1e-59
Identities = 192/764 (25%), Positives = 310/764 (40%), Gaps = 89/764 (11%)
Query: 236 SFDEARKQCQSHGGDLIHGFQGATSSFLTQELERRKAQLKTQLVWIGAQKEPGLTSRTWQ 295
S++ +RK CQ+ DL+ +L + L + WIG +K ++TW
Sbjct: 52 SWNISRKYCQNRYTDLVAIQNKNEIDYLNKVLP-----YYSSYYWIGIRKN----NKTWT 102
Query: 296 WVDGELV---SKPSWGKDQPNNYNGEQNCV---VLDGGRGWLWNDVGCNLDYLHWICQYL 349
WV + +W ++PNN ++CV + WND C L H +C
Sbjct: 103 WVGTKKALTNEAENWADNEPNNKRNNEDCVEIYIKSPSAPGKWNDEHC-LKKKHALCY-- 159
Query: 350 PPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYV 409
T D ++ + G +C E +G+ + C GF+ P C+YV
Sbjct: 160 --TASCQD--MSCSKQG-----------ECLE---TIGNYTCSCYP-GFYG---PECEYV 197
Query: 410 N-CGGLTPIEDGDVALID--NRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRC 466
CG L + + + ++ + C + + + G + C GIW + P+C
Sbjct: 198 RECGELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQC 257
Query: 467 LFDWCPDPPAVSNAS-VTVNGHKA---GSLASYTCENGHILSGSTSVTCTLGGAWSGVPP 522
L CP + + ++ KA S S++CE G L G V CT G W+ P
Sbjct: 258 LAAQCPPLKIPERGNMICLHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASGVWTAPAP 317
Query: 523 SCKYVNCG-TPTIHKGSFVLINGTTT--YGSIAQFTCEPDYWLNGAEELVCNRDGKWSYD 579
CK V C +G+ ++ T YGS +F C+P Y + G + L C G WS
Sbjct: 318 VCKAVQCQHLEAPSEGTMDCVHPLTAFAYGSSCKFECQPGYRVRGLDMLRCIDSGHWSAP 377
Query: 580 IPSCELTSCPEPEVPSGGYME------AFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGE 633
+P+CE SC E P G M+ AF Y + +F C G L G + C G+
Sbjct: 378 LPTCEAISCEPLESPVHGSMDCSPSLRAFQY--DTNCSFRCAEGFMLRGADIVRCDNLGQ 435
Query: 634 WSGDSPTCEYIDCGKLPTLPYGTMELLN--GTTHLGSVIQYSCTTNYRLVGPVRRTCTEE 691
W+ +P C+ + C LP + + G SV ++C LVG C
Sbjct: 436 WTAPAPVCQALQCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLAT 495
Query: 692 FQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKY 751
W+ P C+ I C+ P+++ ++ T ++ + +T ++
Sbjct: 496 GNWNSVPPECQAIPCT-PLLSPQNGTM----------TCVQPLGSSSYKST------CQF 538
Query: 752 RCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFY--GATA 809
C++GY + G C +G+W+ + P C+ + C E G + + G+T
Sbjct: 539 ICDEGYSLSGPERLDCTRSGRWTDSPPMCEAIKCPELFAPEQGSLDCSDTRGEFNVGSTC 598
Query: 810 FYQCDENWELEGVIRRMCQENGTWSLEPPICKEI-TCPDPSAQIKA----GSGLLVVT-- 862
+ C+ ++LEG C +G WS PP CK I + P P Q A G G +
Sbjct: 599 HFSCNNGFKLEGPNNVECTTSGRWSATPPTCKGIASLPTPGLQCPALTTPGQGTMYCRHH 658
Query: 863 -STLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVIS 921
T ++ C G+ L G T +C GQW P C + C + + S
Sbjct: 659 PGTFGFNTTCYFGCNAGFTLIGDSTLSCRPSGQWTAVTPACRAVKCSELHVNKPIAMNCS 718
Query: 922 N--GSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
N G+ +GS ++CL G C ++G WS P+C+
Sbjct: 719 NLWGNFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTCQ 762
Score = 89.0 bits (211), Expect = 8e-17
Identities = 52/201 (25%), Positives = 85/201 (42%), Gaps = 7/201 (3%)
Query: 778 PTCQYV-DCGN---PGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTW 833
P C+YV +CG P + N +F +F+ C + +++ G + C +G W
Sbjct: 192 PECEYVRECGELELPQHVLMNCSHPLGNFSFNSQCSFH-CTDGYQVNGPSKLECLASGIW 250
Query: 834 SLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKG 893
+ +PP C CP + L + CE G+ L G + C + G
Sbjct: 251 TNKPPQCLAAQCPPLKIPERGNMICLHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASG 310
Query: 894 QWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLF--GSSVEYYCLSQYQRVGPFLRKCLD 951
W PVC + C+ G + + T F GSS ++ C Y+ G + +C+D
Sbjct: 311 VWTAPAPVCKAVQCQHLEAPSEGTMDCVHPLTAFAYGSSCKFECQPGYRVRGLDMLRCID 370
Query: 952 DGRWSGEEPSCELATNEAVDS 972
G WS P+CE + E ++S
Sbjct: 371 SGHWSAPLPTCEAISCEPLES 391
Score = 40.7 bits (91), Expect = 0.028
Identities = 15/28 (53%), Positives = 17/28 (60%)
Query: 31 CDEGYELFGARQRECTLRGDWTLEPPFC 58
CDEGY L G + +CT G WT PP C
Sbjct: 540 CDEGYSLSGPERLDCTRSGRWTDSPPMC 567
Score = 36.7 bits (81), Expect = 0.45
Identities = 13/35 (37%), Positives = 19/35 (54%)
Query: 24 GTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
G+ + C+ G++L G ECT G W+ PP C
Sbjct: 595 GSTCHFSCNNGFKLEGPNNVECTTSGRWSATPPTC 629
Score = 35.9 bits (79), Expect = 0.79
Identities = 16/58 (27%), Positives = 28/58 (48%), Gaps = 1/58 (1%)
Query: 2 CGHPAVPPNARVSIPNE-ENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
CG +P + ++ + N + + C +GY++ G + EC G WT +PP C
Sbjct: 200 CGELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQC 257
Score = 34.7 bits (76), Expect = 1.8
Identities = 18/59 (30%), Positives = 27/59 (45%), Gaps = 1/59 (1%)
Query: 1 RCGHPAVPPNARVSIPNEENIVA-GTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
+C VP ARV+ + ++ + C+EG L GA +C G+W PP C
Sbjct: 447 QCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPEC 505
Score = 34.3 bits (75), Expect = 2.4
Identities = 12/30 (40%), Positives = 16/30 (53%)
Query: 29 YECDEGYELFGARQRECTLRGDWTLEPPFC 58
+ C+EG+ L G +CT G WT P C
Sbjct: 290 FSCEEGFALVGPEVVQCTASGVWTAPAPVC 319
Score = 32.3 bits (70), Expect = 9.7
Identities = 20/62 (32%), Positives = 27/62 (43%), Gaps = 3/62 (4%)
Query: 20 NIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTNVAFRKPANQSTTVRGGAA 79
N G+I + C EG L G+ Q C G W+ P C A ++ T GGA
Sbjct: 723 NFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTC---QAGPLTIQEALTYFGGAV 779
Query: 80 AN 81
A+
Sbjct: 780 AS 781
>M26016-1|AAB04638.1| 1033|Homo sapiens CR2 protein.
Length = 1033
Score = 226 bits (552), Expect = 4e-58
Identities = 182/642 (28%), Positives = 265/642 (41%), Gaps = 89/642 (13%)
Query: 372 GSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRTTH 431
G + Y C G++L+G+K +C G WS PP+C+ C L +G V
Sbjct: 176 GLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRV- 234
Query: 432 GARALYSCRENFTLVGNPERTC--GDEGIWDGEAPRCLFDWCPDPPAVSNASVTVN---G 486
G A + C E + L G P C +G+ + P C +CP PP + N N
Sbjct: 235 GVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTKMPVCEEIFCPSPPPILNGRHIGNSLAN 294
Query: 487 HKAGSLASYTC----ENG--HILSGSTSVTCTLG----GAWSGVPPSCKY----VNCGTP 532
GS+ +YTC E G IL G +++ CT+ G WSG P C+ V C P
Sbjct: 295 VSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHP 354
Query: 533 TIHKGSFVL-INGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEP 591
I +G V TY F C + L G++++ CN G W P CE P
Sbjct: 355 QILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKECQAPP 414
Query: 592 EVPSG----GYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCG 647
+ +G +M FD ++I + C G+ L+GE ++ C +G W+ P C+ C
Sbjct: 415 NILNGQKEDRHMVRFD--PGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACE 472
Query: 648 KLPTLPYGTMELLNGTTH--LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIR 705
+LL H + + SC Y+L G V + C W C+EI
Sbjct: 473 AT------GRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEIT 526
Query: 706 CSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKG------YKV 759
C P V N G +L + G V Y C G + +
Sbjct: 527 CPPP--------PVIYNGAHTGSSL----------EDFPYGTTVTYTCNPGPERGVEFSL 568
Query: 760 IGESLSTCEDN----GQWSGTTPTCQY----VDCGNPGRIENG-KVTLPSNATFYGATAF 810
IGES C N G WSG P C+ V C + I NG K++ FY T
Sbjct: 569 IGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHV-HIANGYKISGKEAPYFYNDTVT 627
Query: 811 YQCDENWELEGVIRRMCQENGTWSLEPPICKEITCP---DPSAQIKAGSGLLVVTSTLSI 867
++C + L+G + C+ + TW E P+C++ TC ++ AGS + +V ++
Sbjct: 628 FKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKETCQHVRQSLQELPAGSRVELVNTS--- 684
Query: 868 GGEAHYQCERGYNLKGHQTRTC--ISKGQWNGTVPVCIPIDCRSPGNIENGKIV-ISNGS 924
C+ GY L GH + C G W +P+C I C P I NGK + +
Sbjct: 685 -------CQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAEN 737
Query: 925 TLFGSSVEYYCLSQYQRVGPFLRKCLDD----GRWSGEEPSC 962
L+G+ V Y C + +G +C D G WSG P C
Sbjct: 738 FLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQC 779
Score = 215 bits (524), Expect = 9e-55
Identities = 190/672 (28%), Positives = 277/672 (41%), Gaps = 81/672 (12%)
Query: 352 TCGSPDKLLNTTI--LGNDYDVGSRIVYKCPEGHMLLGDKSRHC----KKDGFWSGAPPS 405
+CGSP +LN I VG+ I Y C L+G+KS C K DG W P
Sbjct: 22 SCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPK 81
Query: 406 CKYVN--CGGLTPIEDGDVALIDNRT-THGARALYSCRENFTLVGNPERTCGDEGIWDG- 461
C+Y N PI G + + HG ++C+ NF++ GN C +W
Sbjct: 82 CEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWGPT 141
Query: 462 EAPRCLFDW---CPDPPAVSNA---SVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGG 515
P C+ + CP P + N S V G +Y+CE+G++L G + C G
Sbjct: 142 RLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSG 201
Query: 516 AWSGVPPSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGK 575
WS VPP+C+ C + V G A F C+ Y L G C G+
Sbjct: 202 KWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQ 261
Query: 576 ---WSYDIPSCELTSCPE-PEVPSGGYM--EAFDYYVHSTINFHCEAGHK------LIGE 623
W+ +P CE CP P + +G ++ + S + + C+ + LIGE
Sbjct: 262 GVAWT-KMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGE 320
Query: 624 PNLVC----QQDGEWSGDSPTCEY----IDCGKLPTLPYGTM--ELLNGTTHLGSVIQYS 673
L C Q+ G WSG +P CE + C P + G M + T+ +VI ++
Sbjct: 321 STLRCTVDSQKTGTWSGPAPRCELSTSAVQCPH-PQILRGRMVSGQKDRYTYNDTVI-FA 378
Query: 674 CTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRT 733
C + L G + C + W S+P CE+ C P +I++ DR ++R
Sbjct: 379 CMFGFTLKGSKQIRCNAQGTWEPSAPVCEK-ECQAP----PNILNGQKEDRH----MVR- 428
Query: 734 SDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIEN 793
+ G +KY C GY ++GE C G W+ P C+ C GR
Sbjct: 429 ---------FDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGR--- 476
Query: 794 GKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIK 853
+T P + F C E ++L G + + CQ W +E +CKEITCP P I
Sbjct: 477 QLLTKPQH-QFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPV-IY 534
Query: 854 AGSGLLVVTSTLSIGGEAHYQC----ERG--YNLKGHQTRTCIS----KGQWNGTVPVC- 902
G+ G Y C ERG ++L G T C S +G W+G P+C
Sbjct: 535 NGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCK 594
Query: 903 ---IPIDCRSPGNIENG-KIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGE 958
+ + C S +I NG KI + +V + C S + G +C D W E
Sbjct: 595 LSLLAVQC-SHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPE 653
Query: 959 EPSCELATNEAV 970
P CE T + V
Sbjct: 654 IPVCEKETCQHV 665
Score = 200 bits (488), Expect = 2e-50
Identities = 156/572 (27%), Positives = 231/572 (40%), Gaps = 70/572 (12%)
Query: 369 YDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNR 428
+D G+ I Y C G++L+G++S C +G W+ P CK C E L+
Sbjct: 429 FDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAAC------EATGRQLLTKP 482
Query: 429 TTHGAR--ALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVT--- 483
R SC E + L G+ + C W E C CP PP + N + T
Sbjct: 483 QHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSS 542
Query: 484 VNGHKAGSLASYTCENG------HILSGSTSVTCTLG----GAWSGVPPSCKY----VNC 529
+ G+ +YTC G L G +++ CT G WSG P CK V C
Sbjct: 543 LEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQC 602
Query: 530 GTPTIHKGSFVLINGTTT---YGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELT 586
+H + I+G Y F C + L G+ ++ C D W +IP CE
Sbjct: 603 SH--VHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKE 660
Query: 587 SCPE-----PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQ--QDGEWSGDSP 639
+C E+P+G +E +N C+ G++L G +CQ ++G W P
Sbjct: 661 TCQHVRQSLQELPAGSRVEL--------VNTSCQDGYQLTGHAYQMCQDAENGIWFKKIP 712
Query: 640 TCEYIDCGKLPTLPYGTMELLNGTTHL-GSVIQYSCTTNYRLVGPVRRTCTEEFQ----W 694
C+ I C P + G + L G+ + Y C + L+G + C + + W
Sbjct: 713 LCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSW 772
Query: 695 SDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCE 754
S SP+C +R S P+ + HG+ L +T + Y +V C
Sbjct: 773 SGPSPQC--LR-SPPVTR------CPNPEVKHGYKLNKTH------SAYSHNDIVYVDCN 817
Query: 755 KGYKVIGESLSTCEDNGQWSGTTPTCQ---YVDCGNPGRIENGKVTLPSNATFY-GATAF 810
G+ + G + C + W PTC ++ C P + NG T + A F G +
Sbjct: 818 PGFIMNGSRVIRCHTDNTWVPGVPTCMKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSIL 877
Query: 811 YQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGE 870
Y CD+ + L G +C GTWS P CKE+ C P+ GL G
Sbjct: 878 YSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVNCSSPADMDGIQKGL-EPRKMYQYGAV 936
Query: 871 AHYQCERGYNLKGHQTRTCISKGQWNGTVPVC 902
+CE GY L+G C S QWN + VC
Sbjct: 937 VTLECEDGYMLEGSPQSQCQSDHQWNPPLAVC 968
Score = 200 bits (487), Expect = 3e-50
Identities = 175/669 (26%), Positives = 267/669 (39%), Gaps = 94/669 (14%)
Query: 353 CGSPDKLLNTTILGN---DYDVGSRIVYKC---PE---GHMLLGDKSRHC----KKDGFW 399
C SP +LN +GN + GS + Y C PE +L+G+ + C +K G W
Sbjct: 276 CPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTW 335
Query: 400 SGAPPSCKY----VNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGD 455
SG P C+ V C + V+ +R T+ +++C FTL G+ + C
Sbjct: 336 SGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNA 395
Query: 456 EGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKA----GSLASYTCENGHILSGSTSVTC 511
+G W+ AP C + C PP + N + H G+ Y+C G++L G S+ C
Sbjct: 396 QGTWEPSAPVCEKE-CQAPPNILNGQKE-DRHMVRFDPGTSIKYSCNPGYVLVGEESIQC 453
Query: 512 TLGGAWSGVPPSCKYVNC---GTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEEL 568
T G W+ P CK C G + K + +C Y L+G+
Sbjct: 454 TSEGVWTPPVPQCKVAACEATGRQLLTKPQHQFVRPDVNS------SCGEGYKLSGSVYQ 507
Query: 569 VCNRDGKWSYDIPSCELTSCPEPEV-----PSGGYMEAFDYYVHSTINFHCEAGHK---- 619
C W +I C+ +CP P V +G +E F Y +T+ + C G +
Sbjct: 508 ECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPY--GTTVTYTCNPGPERGVE 565
Query: 620 --LIGEPNLVC----QQDGEWSGDSPTCEY----IDCGKLPTLPYGTMELLNGTTHLGSV 669
LIGE + C Q+ G WSG +P C+ + C + +
Sbjct: 566 FSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDT 625
Query: 670 IQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHT 729
+ + C + + L G + C + W P CE+ C +S+ + R
Sbjct: 626 VTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKETCQH---VRQSLQELPAGSRVE--- 679
Query: 730 LIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCED--NGQWSGTTPTCQYVDCGN 787
L+ TS C+ GY++ G + C+D NG W P C+ + C
Sbjct: 680 LVNTS------------------CQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHP 721
Query: 788 PGRIENGKVT-LPSNATFYGATAFYQCDENWELEGVIRRMCQEN----GTWSLEPPICKE 842
P I NGK T + + YG Y+CD+ + L G + C+ + G+WS P C
Sbjct: 722 PPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLR 781
Query: 843 ---IT-CPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGT 898
+T CP+P ++K G L S S + C G+ + G + C + W
Sbjct: 782 SPPVTRCPNP--EVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPG 839
Query: 899 VPVCIP---IDCRSPGNIENGKIVISNGSTLF-GSSVEYYCLSQYQRVGPFLRKCLDDGR 954
VP C+ I C P NG N + G S+ Y C Y VG L C +G
Sbjct: 840 VPTCMKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGT 899
Query: 955 WSGEEPSCE 963
WS P C+
Sbjct: 900 WSQPAPHCK 908
Score = 178 bits (433), Expect = 1e-43
Identities = 159/612 (25%), Positives = 239/612 (39%), Gaps = 81/612 (13%)
Query: 404 PSCKYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTC----GDEGIW 459
P ++CG PI +G ++ G YSC F L+G C +G W
Sbjct: 16 PGVLGISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTW 75
Query: 460 DGEAPRC----LFDWCPDPPAVSNASVT-VNGHKAGSLASYTCENGHILSGSTSVTCTLG 514
D AP+C + CP+P + ++ G ++ C+ ++G+ SV C
Sbjct: 76 DKPAPKCEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQAN 135
Query: 515 GAWSGVP-PSCKYV---NC-GTPTIHKGSFVLIN-GTTTYGSIAQFTCEPDYWLNGAEEL 568
W P+C V C P IH G N G+ G ++CE Y L G + +
Sbjct: 136 NMWGPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKII 195
Query: 569 VCNRDGKWSYDIPSCELTSCPE-PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLV 627
C GKWS P+CE C P+G E V T NF C+ G++L G P+
Sbjct: 196 NCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSR 255
Query: 628 CQQDGE---WSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHL--GSVIQYSCT------T 676
C G+ W+ P CE I C P + G + N ++ GS++ Y+C
Sbjct: 256 CVIAGQGVAWT-KMPVCEEIFCPSPPPILNG-RHIGNSLANVSYGSIVTYTCDPDPEEGV 313
Query: 677 NYRLVGPVRRTCTEEFQ----WSDSSPRCE----EIRCSDPIVAEKSIVSVTGNDRSHGH 728
N+ L+G CT + Q WS +PRCE ++C P + +VS + ++
Sbjct: 314 NFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYTYND 373
Query: 729 TLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNP 788
T+I + C G+ + G C G W + P C+ +C P
Sbjct: 374 TVI-------------------FACMFGFTLKGSKQIRCNAQGTWEPSAPVCE-KECQAP 413
Query: 789 GRIENGKVTLPSNATFYGATAF-YQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPD 847
I NG+ F T+ Y C+ + L G C G W+ P CK C
Sbjct: 414 PNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACE- 472
Query: 848 PSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDC 907
G LL + + + C GY L G + C W + +C I C
Sbjct: 473 -----ATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITC 527
Query: 908 RSPGNIENGKIVISNGSTL----FGSSVEYYCLS------QYQRVGPFLRKCLDD----G 953
P I NG GS+L +G++V Y C ++ +G +C + G
Sbjct: 528 PPPPVIYNG---AHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERG 584
Query: 954 RWSGEEPSCELA 965
WSG P C+L+
Sbjct: 585 TWSGPAPLCKLS 596
Score = 174 bits (423), Expect = 2e-42
Identities = 160/642 (24%), Positives = 244/642 (38%), Gaps = 68/642 (10%)
Query: 353 CGSPDKLLNTTILGND--YDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVN 410
C P L + G Y +++ C G L G K C G W + P C+
Sbjct: 351 CPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEK-E 409
Query: 411 CGGLTPIEDG---DVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL 467
C I +G D ++ R G YSC + LVG C EG+W P+C
Sbjct: 410 CQAPPNILNGQKEDRHMV--RFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCK 467
Query: 468 FDWCPDPPAVSNASVTVNGHK-AGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKY 526
C A +T H+ + +C G+ LSGS C W CK
Sbjct: 468 VAACE---ATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKE 524
Query: 527 VNCGTP-TIHKGSFVLIN-GTTTYGSIAQFTCEP------DYWLNGAEELVCNRD----G 574
+ C P I+ G+ + YG+ +TC P ++ L G + C + G
Sbjct: 525 ITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERG 584
Query: 575 KWSYDIPSCELT----SCPEPEVPSGGYMEAFD--YYVHSTINFHCEAGHKLIGEPNLVC 628
WS P C+L+ C + +G + + Y+ + T+ F C +G L G + C
Sbjct: 585 TWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRC 644
Query: 629 QQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTC 688
+ D W + P CE C + EL G+ ++ SC Y+L G + C
Sbjct: 645 KADNTWDPEIPVCEKETCQHVRQ---SLQELPAGSRV--ELVNTSCQDGYQLTGHAYQMC 699
Query: 689 --TEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIG 746
E W P C+ I C P V V G HT + ++N GN
Sbjct: 700 QDAENGIWFKKIPLCKVIHCHPPPVI------VNGK-----HTGMM-AENFLYGNE---- 743
Query: 747 ALVKYRCEKGYKVIGESLSTCEDN----GQWSGTTPTC----QYVDCGNPGRIENGKVTL 798
V Y C++G+ ++GE C + G WSG +P C C NP K+
Sbjct: 744 --VSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNK 801
Query: 799 PSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKE---ITCPDPSAQIKAG 855
+A + + C+ + + G C + TW P C + I CP P + G
Sbjct: 802 THSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPTCMKKAFIGCPPPP-KTPNG 860
Query: 856 SGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIEN 915
+ + S G Y C++GY L G C +G W+ P C ++C SP +++
Sbjct: 861 NHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVNCSSPADMDG 920
Query: 916 -GKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWS 956
K + +G+ V C Y G +C D +W+
Sbjct: 921 IQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSDHQWN 962
Score = 152 bits (369), Expect = 6e-36
Identities = 123/465 (26%), Positives = 182/465 (39%), Gaps = 56/465 (12%)
Query: 352 TCGSPDKLLNTTILGN---DYDVGSRIVYKCPEG------HMLLGDKSRHCKKD----GF 398
TC P + N G+ D+ G+ + Y C G L+G+ + C + G
Sbjct: 526 TCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGT 585
Query: 399 WSGAPPSCKY----VNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCG 454
WSG P CK V C + ++ + + + C FTL G+ + C
Sbjct: 586 WSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCK 645
Query: 455 DEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTC--T 512
+ WD E P C + C V + + L + +C++G+ L+G C
Sbjct: 646 ADNTWDPEIPVCEKETCQH---VRQSLQELPAGSRVELVNTSCQDGYQLTGHAYQMCQDA 702
Query: 513 LGGAWSGVPPSCKYVNCGTP-TIHKGSFV-LINGTTTYGSIAQFTCEPDYWLNGAEELVC 570
G W P CK ++C P I G ++ YG+ + C+ ++L G ++L C
Sbjct: 703 ENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQC 762
Query: 571 NRD----GKWSYDIPSC----ELTSCPEPEVPSGGYM-EAFDYYVHSTINF-HCEAGHKL 620
D G WS P C +T CP PEV G + + Y H+ I + C G +
Sbjct: 763 RSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIM 822
Query: 621 IGEPNLVCQQDGEWSGDSPTC---EYIDCGKLPTLPYGTMELLN-GTTHLGSVIQYSCTT 676
G + C D W PTC +I C P P G N G I YSC
Sbjct: 823 NGSRVIRCHTDNTWVPGVPTCMKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQ 882
Query: 677 NYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDN 736
Y LVG CT E WS +P C+E+ CS P + G +
Sbjct: 883 GYLLVGEALLLCTHEGTWSQPAPHCKEVNCSSP-------ADMDGIQK-----------G 924
Query: 737 RDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQ 781
+ Y+ GA+V CE GY + G S C+ + QW+ C+
Sbjct: 925 LEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSDHQWNPPLAVCR 969
Score = 138 bits (333), Expect = 1e-31
Identities = 129/528 (24%), Positives = 205/528 (38%), Gaps = 66/528 (12%)
Query: 379 CPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDG-DVALIDNRTTHGARALY 437
C EG+ L G + C+ W CK + C I +G +G Y
Sbjct: 495 CGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTY 554
Query: 438 SCREN------FTLVGNPERTCG----DEGIWDGEAPRCLFDWCPDPPAVSNASVTV-NG 486
+C F+L+G C + G W G AP C AV + V + NG
Sbjct: 555 TCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLL----AVQCSHVHIANG 610
Query: 487 HK-AGSLASY--------TCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTIHKG 537
+K +G A Y C +G L GS+ + C W P C+ C + +
Sbjct: 611 YKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKETC--QHVRQS 668
Query: 538 SFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCN--RDGKWSYDIPSCELTSC-PEPEVP 594
L G+ + +C+ Y L G +C +G W IP C++ C P P +
Sbjct: 669 LQELPAGSRV--ELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIV 726
Query: 595 SGGY--MEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQD----GEWSGDSPTC----EYI 644
+G + M A ++ + +++ C+ G L+GE L C+ D G WSG SP C
Sbjct: 727 NGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVT 786
Query: 645 DCGKLPTLPYG-TMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEE 703
C P + +G + + ++ C + + G C + W P C +
Sbjct: 787 RCPN-PEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPTCMK 845
Query: 704 ---IRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVI 760
I C P T N G + R S G + Y C++GY ++
Sbjct: 846 KAFIGCPPP--------PKTPNGNHTGGNIARFSP----------GMSILYSCDQGYLLV 887
Query: 761 GESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTL-PSNATFYGATAFYQCDENWEL 819
GE+L C G WS P C+ V+C +P ++ + L P YGA +C++ + L
Sbjct: 888 GEALLLCTHEGTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYML 947
Query: 820 EGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSI 867
EG + CQ + W+ +C+ + I AG LL +++
Sbjct: 948 EGSPQSQCQSDHQWNPPLAVCRSRSLAPVLCGIAAGLILLTFLIVITL 995
Score = 108 bits (259), Expect = 1e-22
Identities = 71/256 (27%), Positives = 106/256 (41%), Gaps = 23/256 (8%)
Query: 353 CGSPDKLLN---TTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKD----GFWSGAPPS 405
C P ++N T ++ ++ G+ + Y+C +G LLG+K C+ D G WSG P
Sbjct: 719 CHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQ 778
Query: 406 CKYVNCGGLTPIEDGDVALIDNRT----THGARALYSCRENFTLVGNPERTCGDEGIWDG 461
C P + N+T +H C F + G+ C + W
Sbjct: 779 CLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVP 838
Query: 462 EAPRCL---FDWCPDPPAVSNASVT---VNGHKAGSLASYTCENGHILSGSTSVTCTLGG 515
P C+ F CP PP N + T + G Y+C+ G++L G + CT G
Sbjct: 839 GVPTCMKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEG 898
Query: 516 AWSGVPPSCKYVNCGTPT----IHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCN 571
WS P CK VNC +P I KG + YG++ CE Y L G+ + C
Sbjct: 899 TWSQPAPHCKEVNCSSPADMDGIQKG--LEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQ 956
Query: 572 RDGKWSYDIPSCELTS 587
D +W+ + C S
Sbjct: 957 SDHQWNPPLAVCRSRS 972
Score = 40.3 bits (90), Expect = 0.037
Identities = 23/75 (30%), Positives = 29/75 (38%), Gaps = 1/75 (1%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTN 61
C P PN + N G +Y CD+GY L G CT G W+ P C
Sbjct: 851 CPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHC-KE 909
Query: 62 VAFRKPANQSTTVRG 76
V PA+ +G
Sbjct: 910 VNCSSPADMDGIQKG 924
Score = 38.7 bits (86), Expect = 0.11
Identities = 19/56 (33%), Positives = 25/56 (44%), Gaps = 2/56 (3%)
Query: 5 PAVPP--NARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
PA+P N + N +I G Y C+ GY L G + C G W+ PP C
Sbjct: 155 PALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTC 210
Score = 36.3 bits (80), Expect = 0.60
Identities = 19/54 (35%), Positives = 24/54 (44%), Gaps = 3/54 (5%)
Query: 8 PPNARVSIPNEENIVA---GTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
PPN + ++V GT Y C+ GY L G +CT G WT P C
Sbjct: 413 PPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQC 466
Score = 36.3 bits (80), Expect = 0.60
Identities = 19/61 (31%), Positives = 28/61 (45%), Gaps = 4/61 (6%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTL----RGDWTLEPPF 57
C P V N + + EN + G YECD+G+ L G ++ +C G W+ P
Sbjct: 719 CHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQ 778
Query: 58 C 58
C
Sbjct: 779 C 779
Score = 34.7 bits (76), Expect = 1.8
Identities = 16/58 (27%), Positives = 26/58 (44%), Gaps = 1/58 (1%)
Query: 1 RCGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
+C HP + VS + T+ ++ C G+ L G++Q C +G W P C
Sbjct: 350 QCPHPQILRGRMVSGQKDRYTYNDTV-IFACMFGFTLKGSKQIRCNAQGTWEPSAPVC 406
>M26004-1|AAA35786.1| 1033|Homo sapiens CR2 protein.
Length = 1033
Score = 226 bits (552), Expect = 4e-58
Identities = 182/642 (28%), Positives = 265/642 (41%), Gaps = 89/642 (13%)
Query: 372 GSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRTTH 431
G + Y C G++L+G+K +C G WS PP+C+ C L +G V
Sbjct: 176 GLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRV- 234
Query: 432 GARALYSCRENFTLVGNPERTC--GDEGIWDGEAPRCLFDWCPDPPAVSNASVTVN---G 486
G A + C E + L G P C +G+ + P C +CP PP + N N
Sbjct: 235 GVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTKMPVCEEIFCPSPPPILNGRHIGNSLAN 294
Query: 487 HKAGSLASYTC----ENG--HILSGSTSVTCTLG----GAWSGVPPSCKY----VNCGTP 532
GS+ +YTC E G IL G +++ CT+ G WSG P C+ V C P
Sbjct: 295 VSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHP 354
Query: 533 TIHKGSFVL-INGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEP 591
I +G V TY F C + L G++++ CN G W P CE P
Sbjct: 355 QILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKECQAPP 414
Query: 592 EVPSG----GYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCG 647
+ +G +M FD ++I + C G+ L+GE ++ C +G W+ P C+ C
Sbjct: 415 NILNGQKEDRHMVRFD--PGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACE 472
Query: 648 KLPTLPYGTMELLNGTTH--LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIR 705
+LL H + + SC Y+L G V + C W C+EI
Sbjct: 473 AT------GRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEIT 526
Query: 706 CSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKG------YKV 759
C P V N G +L + G V Y C G + +
Sbjct: 527 CPPP--------PVIYNGAHTGSSL----------EDFPYGTTVTYTCNPGPERGVEFSL 568
Query: 760 IGESLSTCEDN----GQWSGTTPTCQY----VDCGNPGRIENG-KVTLPSNATFYGATAF 810
IGES C N G WSG P C+ V C + I NG K++ FY T
Sbjct: 569 IGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHV-HIANGYKISGKEAPYFYNDTVT 627
Query: 811 YQCDENWELEGVIRRMCQENGTWSLEPPICKEITCP---DPSAQIKAGSGLLVVTSTLSI 867
++C + L+G + C+ + TW E P+C++ TC ++ AGS + +V ++
Sbjct: 628 FKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKETCQHVRQSLQELPAGSRVELVNTS--- 684
Query: 868 GGEAHYQCERGYNLKGHQTRTC--ISKGQWNGTVPVCIPIDCRSPGNIENGKIV-ISNGS 924
C+ GY L GH + C G W +P+C I C P I NGK + +
Sbjct: 685 -------CQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAEN 737
Query: 925 TLFGSSVEYYCLSQYQRVGPFLRKCLDD----GRWSGEEPSC 962
L+G+ V Y C + +G +C D G WSG P C
Sbjct: 738 FLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQC 779
Score = 215 bits (524), Expect = 9e-55
Identities = 190/672 (28%), Positives = 277/672 (41%), Gaps = 81/672 (12%)
Query: 352 TCGSPDKLLNTTI--LGNDYDVGSRIVYKCPEGHMLLGDKSRHC----KKDGFWSGAPPS 405
+CGSP +LN I VG+ I Y C L+G+KS C K DG W P
Sbjct: 22 SCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPK 81
Query: 406 CKYVN--CGGLTPIEDGDVALIDNRT-THGARALYSCRENFTLVGNPERTCGDEGIWDG- 461
C+Y N PI G + + HG ++C+ NF++ GN C +W
Sbjct: 82 CEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWGPT 141
Query: 462 EAPRCLFDW---CPDPPAVSNA---SVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGG 515
P C+ + CP P + N S V G +Y+CE+G++L G + C G
Sbjct: 142 RLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSG 201
Query: 516 AWSGVPPSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGK 575
WS VPP+C+ C + V G A F C+ Y L G C G+
Sbjct: 202 KWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQ 261
Query: 576 ---WSYDIPSCELTSCPE-PEVPSGGYM--EAFDYYVHSTINFHCEAGHK------LIGE 623
W+ +P CE CP P + +G ++ + S + + C+ + LIGE
Sbjct: 262 GVAWT-KMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGE 320
Query: 624 PNLVC----QQDGEWSGDSPTCEY----IDCGKLPTLPYGTM--ELLNGTTHLGSVIQYS 673
L C Q+ G WSG +P CE + C P + G M + T+ +VI ++
Sbjct: 321 STLRCTVDSQKTGTWSGPAPRCELSTSAVQCPH-PQILRGRMVSGQKDRYTYNDTVI-FA 378
Query: 674 CTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRT 733
C + L G + C + W S+P CE+ C P +I++ DR ++R
Sbjct: 379 CMFGFTLKGSKQIRCNAQGTWEPSAPVCEK-ECQAP----PNILNGQKEDRH----MVR- 428
Query: 734 SDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIEN 793
+ G +KY C GY ++GE C G W+ P C+ C GR
Sbjct: 429 ---------FDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGR--- 476
Query: 794 GKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIK 853
+T P + F C E ++L G + + CQ W +E +CKEITCP P I
Sbjct: 477 QLLTKPQH-QFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPV-IY 534
Query: 854 AGSGLLVVTSTLSIGGEAHYQC----ERG--YNLKGHQTRTCIS----KGQWNGTVPVC- 902
G+ G Y C ERG ++L G T C S +G W+G P+C
Sbjct: 535 NGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCK 594
Query: 903 ---IPIDCRSPGNIENG-KIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGE 958
+ + C S +I NG KI + +V + C S + G +C D W E
Sbjct: 595 LSLLAVQC-SHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPE 653
Query: 959 EPSCELATNEAV 970
P CE T + V
Sbjct: 654 IPVCEKETCQHV 665
Score = 200 bits (488), Expect = 2e-50
Identities = 156/572 (27%), Positives = 231/572 (40%), Gaps = 70/572 (12%)
Query: 369 YDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNR 428
+D G+ I Y C G++L+G++S C +G W+ P CK C E L+
Sbjct: 429 FDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAAC------EATGRQLLTKP 482
Query: 429 TTHGAR--ALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVT--- 483
R SC E + L G+ + C W E C CP PP + N + T
Sbjct: 483 QHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSS 542
Query: 484 VNGHKAGSLASYTCENG------HILSGSTSVTCTLG----GAWSGVPPSCKY----VNC 529
+ G+ +YTC G L G +++ CT G WSG P CK V C
Sbjct: 543 LEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQC 602
Query: 530 GTPTIHKGSFVLINGTTT---YGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELT 586
+H + I+G Y F C + L G+ ++ C D W +IP CE
Sbjct: 603 SH--VHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKE 660
Query: 587 SCPE-----PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQ--QDGEWSGDSP 639
+C E+P+G +E +N C+ G++L G +CQ ++G W P
Sbjct: 661 TCQHVRQSLQELPAGSRVEL--------VNTSCQDGYQLTGHAYQMCQDAENGIWFKKIP 712
Query: 640 TCEYIDCGKLPTLPYGTMELLNGTTHL-GSVIQYSCTTNYRLVGPVRRTCTEEFQ----W 694
C+ I C P + G + L G+ + Y C + L+G + C + + W
Sbjct: 713 LCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSW 772
Query: 695 SDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCE 754
S SP+C +R S P+ + HG+ L +T + Y +V C
Sbjct: 773 SGPSPQC--LR-SPPVTR------CPNPEVKHGYKLNKTH------SAYSHNDIVYVDCN 817
Query: 755 KGYKVIGESLSTCEDNGQWSGTTPTCQ---YVDCGNPGRIENGKVTLPSNATFY-GATAF 810
G+ + G + C + W PTC ++ C P + NG T + A F G +
Sbjct: 818 PGFIMNGSRVIRCHTDNTWVPGVPTCMKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSIL 877
Query: 811 YQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGE 870
Y CD+ + L G +C GTWS P CKE+ C P+ GL G
Sbjct: 878 YSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVNCSSPADMDGIQKGL-EPRKMYQYGAV 936
Query: 871 AHYQCERGYNLKGHQTRTCISKGQWNGTVPVC 902
+CE GY L+G C S QWN + VC
Sbjct: 937 VTLECEDGYMLEGSPQSQCQSDHQWNPPLAVC 968
Score = 200 bits (487), Expect = 3e-50
Identities = 175/669 (26%), Positives = 267/669 (39%), Gaps = 94/669 (14%)
Query: 353 CGSPDKLLNTTILGN---DYDVGSRIVYKC---PE---GHMLLGDKSRHC----KKDGFW 399
C SP +LN +GN + GS + Y C PE +L+G+ + C +K G W
Sbjct: 276 CPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTW 335
Query: 400 SGAPPSCKY----VNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGD 455
SG P C+ V C + V+ +R T+ +++C FTL G+ + C
Sbjct: 336 SGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNA 395
Query: 456 EGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKA----GSLASYTCENGHILSGSTSVTC 511
+G W+ AP C + C PP + N + H G+ Y+C G++L G S+ C
Sbjct: 396 QGTWEPSAPVCEKE-CQAPPNILNGQKE-DRHMVRFDPGTSIKYSCNPGYVLVGEESIQC 453
Query: 512 TLGGAWSGVPPSCKYVNC---GTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEEL 568
T G W+ P CK C G + K + +C Y L+G+
Sbjct: 454 TSEGVWTPPVPQCKVAACEATGRQLLTKPQHQFVRPDVNS------SCGEGYKLSGSVYQ 507
Query: 569 VCNRDGKWSYDIPSCELTSCPEPEV-----PSGGYMEAFDYYVHSTINFHCEAGHK---- 619
C W +I C+ +CP P V +G +E F Y +T+ + C G +
Sbjct: 508 ECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPY--GTTVTYTCNPGPERGVE 565
Query: 620 --LIGEPNLVC----QQDGEWSGDSPTCEY----IDCGKLPTLPYGTMELLNGTTHLGSV 669
LIGE + C Q+ G WSG +P C+ + C + +
Sbjct: 566 FSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDT 625
Query: 670 IQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHT 729
+ + C + + L G + C + W P CE+ C +S+ + R
Sbjct: 626 VTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKETCQH---VRQSLQELPAGSRVE--- 679
Query: 730 LIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCED--NGQWSGTTPTCQYVDCGN 787
L+ TS C+ GY++ G + C+D NG W P C+ + C
Sbjct: 680 LVNTS------------------CQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHP 721
Query: 788 PGRIENGKVT-LPSNATFYGATAFYQCDENWELEGVIRRMCQEN----GTWSLEPPICKE 842
P I NGK T + + YG Y+CD+ + L G + C+ + G+WS P C
Sbjct: 722 PPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLR 781
Query: 843 ---IT-CPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGT 898
+T CP+P ++K G L S S + C G+ + G + C + W
Sbjct: 782 SPPVTRCPNP--EVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPG 839
Query: 899 VPVCIP---IDCRSPGNIENGKIVISNGSTLF-GSSVEYYCLSQYQRVGPFLRKCLDDGR 954
VP C+ I C P NG N + G S+ Y C Y VG L C +G
Sbjct: 840 VPTCMKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGT 899
Query: 955 WSGEEPSCE 963
WS P C+
Sbjct: 900 WSQPAPHCK 908
Score = 178 bits (433), Expect = 1e-43
Identities = 159/612 (25%), Positives = 239/612 (39%), Gaps = 81/612 (13%)
Query: 404 PSCKYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTC----GDEGIW 459
P ++CG PI +G ++ G YSC F L+G C +G W
Sbjct: 16 PGVLGISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTW 75
Query: 460 DGEAPRC----LFDWCPDPPAVSNASVT-VNGHKAGSLASYTCENGHILSGSTSVTCTLG 514
D AP+C + CP+P + ++ G ++ C+ ++G+ SV C
Sbjct: 76 DKPAPKCEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQAN 135
Query: 515 GAWSGVP-PSCKYV---NC-GTPTIHKGSFVLIN-GTTTYGSIAQFTCEPDYWLNGAEEL 568
W P+C V C P IH G N G+ G ++CE Y L G + +
Sbjct: 136 NMWGPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKII 195
Query: 569 VCNRDGKWSYDIPSCELTSCPE-PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLV 627
C GKWS P+CE C P+G E V T NF C+ G++L G P+
Sbjct: 196 NCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSR 255
Query: 628 CQQDGE---WSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHL--GSVIQYSCT------T 676
C G+ W+ P CE I C P + G + N ++ GS++ Y+C
Sbjct: 256 CVIAGQGVAWT-KMPVCEEIFCPSPPPILNG-RHIGNSLANVSYGSIVTYTCDPDPEEGV 313
Query: 677 NYRLVGPVRRTCTEEFQ----WSDSSPRCE----EIRCSDPIVAEKSIVSVTGNDRSHGH 728
N+ L+G CT + Q WS +PRCE ++C P + +VS + ++
Sbjct: 314 NFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYTYND 373
Query: 729 TLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNP 788
T+I + C G+ + G C G W + P C+ +C P
Sbjct: 374 TVI-------------------FACMFGFTLKGSKQIRCNAQGTWEPSAPVCE-KECQAP 413
Query: 789 GRIENGKVTLPSNATFYGATAF-YQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPD 847
I NG+ F T+ Y C+ + L G C G W+ P CK C
Sbjct: 414 PNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACE- 472
Query: 848 PSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDC 907
G LL + + + C GY L G + C W + +C I C
Sbjct: 473 -----ATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITC 527
Query: 908 RSPGNIENGKIVISNGSTL----FGSSVEYYCLS------QYQRVGPFLRKCLDD----G 953
P I NG GS+L +G++V Y C ++ +G +C + G
Sbjct: 528 PPPPVIYNG---AHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERG 584
Query: 954 RWSGEEPSCELA 965
WSG P C+L+
Sbjct: 585 TWSGPAPLCKLS 596
Score = 174 bits (423), Expect = 2e-42
Identities = 160/642 (24%), Positives = 244/642 (38%), Gaps = 68/642 (10%)
Query: 353 CGSPDKLLNTTILGND--YDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVN 410
C P L + G Y +++ C G L G K C G W + P C+
Sbjct: 351 CPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEK-E 409
Query: 411 CGGLTPIEDG---DVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL 467
C I +G D ++ R G YSC + LVG C EG+W P+C
Sbjct: 410 CQAPPNILNGQKEDRHMV--RFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCK 467
Query: 468 FDWCPDPPAVSNASVTVNGHK-AGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKY 526
C A +T H+ + +C G+ LSGS C W CK
Sbjct: 468 VAACE---ATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKE 524
Query: 527 VNCGTP-TIHKGSFVLIN-GTTTYGSIAQFTCEP------DYWLNGAEELVCNRD----G 574
+ C P I+ G+ + YG+ +TC P ++ L G + C + G
Sbjct: 525 ITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERG 584
Query: 575 KWSYDIPSCELT----SCPEPEVPSGGYMEAFD--YYVHSTINFHCEAGHKLIGEPNLVC 628
WS P C+L+ C + +G + + Y+ + T+ F C +G L G + C
Sbjct: 585 TWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRC 644
Query: 629 QQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTC 688
+ D W + P CE C + EL G+ ++ SC Y+L G + C
Sbjct: 645 KADNTWDPEIPVCEKETCQHVRQ---SLQELPAGSRV--ELVNTSCQDGYQLTGHAYQMC 699
Query: 689 --TEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIG 746
E W P C+ I C P V V G HT + ++N GN
Sbjct: 700 QDAENGIWFKKIPLCKVIHCHPPPVI------VNGK-----HTGMM-AENFLYGNE---- 743
Query: 747 ALVKYRCEKGYKVIGESLSTCEDN----GQWSGTTPTC----QYVDCGNPGRIENGKVTL 798
V Y C++G+ ++GE C + G WSG +P C C NP K+
Sbjct: 744 --VSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNK 801
Query: 799 PSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKE---ITCPDPSAQIKAG 855
+A + + C+ + + G C + TW P C + I CP P + G
Sbjct: 802 THSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPTCMKKAFIGCPPPP-KTPNG 860
Query: 856 SGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIEN 915
+ + S G Y C++GY L G C +G W+ P C ++C SP +++
Sbjct: 861 NHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVNCSSPADMDG 920
Query: 916 -GKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWS 956
K + +G+ V C Y G +C D +W+
Sbjct: 921 IQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSDHQWN 962
Score = 152 bits (369), Expect = 6e-36
Identities = 123/465 (26%), Positives = 182/465 (39%), Gaps = 56/465 (12%)
Query: 352 TCGSPDKLLNTTILGN---DYDVGSRIVYKCPEG------HMLLGDKSRHCKKD----GF 398
TC P + N G+ D+ G+ + Y C G L+G+ + C + G
Sbjct: 526 TCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGT 585
Query: 399 WSGAPPSCKY----VNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCG 454
WSG P CK V C + ++ + + + C FTL G+ + C
Sbjct: 586 WSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCK 645
Query: 455 DEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTC--T 512
+ WD E P C + C V + + L + +C++G+ L+G C
Sbjct: 646 ADNTWDPEIPVCEKETCQH---VRQSLQELPAGSRVELVNTSCQDGYQLTGHAYQMCQDA 702
Query: 513 LGGAWSGVPPSCKYVNCGTP-TIHKGSFV-LINGTTTYGSIAQFTCEPDYWLNGAEELVC 570
G W P CK ++C P I G ++ YG+ + C+ ++L G ++L C
Sbjct: 703 ENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQC 762
Query: 571 NRD----GKWSYDIPSC----ELTSCPEPEVPSGGYM-EAFDYYVHSTINF-HCEAGHKL 620
D G WS P C +T CP PEV G + + Y H+ I + C G +
Sbjct: 763 RSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIM 822
Query: 621 IGEPNLVCQQDGEWSGDSPTC---EYIDCGKLPTLPYGTMELLN-GTTHLGSVIQYSCTT 676
G + C D W PTC +I C P P G N G I YSC
Sbjct: 823 NGSRVIRCHTDNTWVPGVPTCMKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQ 882
Query: 677 NYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDN 736
Y LVG CT E WS +P C+E+ CS P + G +
Sbjct: 883 GYLLVGEALLLCTHEGTWSQPAPHCKEVNCSSP-------ADMDGIQK-----------G 924
Query: 737 RDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQ 781
+ Y+ GA+V CE GY + G S C+ + QW+ C+
Sbjct: 925 LEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSDHQWNPPLAVCR 969
Score = 138 bits (333), Expect = 1e-31
Identities = 129/528 (24%), Positives = 205/528 (38%), Gaps = 66/528 (12%)
Query: 379 CPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDG-DVALIDNRTTHGARALY 437
C EG+ L G + C+ W CK + C I +G +G Y
Sbjct: 495 CGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTY 554
Query: 438 SCREN------FTLVGNPERTCG----DEGIWDGEAPRCLFDWCPDPPAVSNASVTV-NG 486
+C F+L+G C + G W G AP C AV + V + NG
Sbjct: 555 TCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLL----AVQCSHVHIANG 610
Query: 487 HK-AGSLASY--------TCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTIHKG 537
+K +G A Y C +G L GS+ + C W P C+ C + +
Sbjct: 611 YKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKETC--QHVRQS 668
Query: 538 SFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCN--RDGKWSYDIPSCELTSC-PEPEVP 594
L G+ + +C+ Y L G +C +G W IP C++ C P P +
Sbjct: 669 LQELPAGSRV--ELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIV 726
Query: 595 SGGY--MEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQD----GEWSGDSPTC----EYI 644
+G + M A ++ + +++ C+ G L+GE L C+ D G WSG SP C
Sbjct: 727 NGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVT 786
Query: 645 DCGKLPTLPYG-TMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEE 703
C P + +G + + ++ C + + G C + W P C +
Sbjct: 787 RCPN-PEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPTCMK 845
Query: 704 ---IRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVI 760
I C P T N G + R S G + Y C++GY ++
Sbjct: 846 KAFIGCPPP--------PKTPNGNHTGGNIARFSP----------GMSILYSCDQGYLLV 887
Query: 761 GESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTL-PSNATFYGATAFYQCDENWEL 819
GE+L C G WS P C+ V+C +P ++ + L P YGA +C++ + L
Sbjct: 888 GEALLLCTHEGTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYML 947
Query: 820 EGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSI 867
EG + CQ + W+ +C+ + I AG LL +++
Sbjct: 948 EGSPQSQCQSDHQWNPPLAVCRSRSLAPVLCGIAAGLILLTFLIVITL 995
Score = 108 bits (259), Expect = 1e-22
Identities = 71/256 (27%), Positives = 106/256 (41%), Gaps = 23/256 (8%)
Query: 353 CGSPDKLLN---TTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKD----GFWSGAPPS 405
C P ++N T ++ ++ G+ + Y+C +G LLG+K C+ D G WSG P
Sbjct: 719 CHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQ 778
Query: 406 CKYVNCGGLTPIEDGDVALIDNRT----THGARALYSCRENFTLVGNPERTCGDEGIWDG 461
C P + N+T +H C F + G+ C + W
Sbjct: 779 CLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVP 838
Query: 462 EAPRCL---FDWCPDPPAVSNASVT---VNGHKAGSLASYTCENGHILSGSTSVTCTLGG 515
P C+ F CP PP N + T + G Y+C+ G++L G + CT G
Sbjct: 839 GVPTCMKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEG 898
Query: 516 AWSGVPPSCKYVNCGTPT----IHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCN 571
WS P CK VNC +P I KG + YG++ CE Y L G+ + C
Sbjct: 899 TWSQPAPHCKEVNCSSPADMDGIQKG--LEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQ 956
Query: 572 RDGKWSYDIPSCELTS 587
D +W+ + C S
Sbjct: 957 SDHQWNPPLAVCRSRS 972
Score = 40.3 bits (90), Expect = 0.037
Identities = 23/75 (30%), Positives = 29/75 (38%), Gaps = 1/75 (1%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTN 61
C P PN + N G +Y CD+GY L G CT G W+ P C
Sbjct: 851 CPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHC-KE 909
Query: 62 VAFRKPANQSTTVRG 76
V PA+ +G
Sbjct: 910 VNCSSPADMDGIQKG 924
Score = 38.7 bits (86), Expect = 0.11
Identities = 19/56 (33%), Positives = 25/56 (44%), Gaps = 2/56 (3%)
Query: 5 PAVPP--NARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
PA+P N + N +I G Y C+ GY L G + C G W+ PP C
Sbjct: 155 PALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTC 210
Score = 36.3 bits (80), Expect = 0.60
Identities = 19/54 (35%), Positives = 24/54 (44%), Gaps = 3/54 (5%)
Query: 8 PPNARVSIPNEENIVA---GTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
PPN + ++V GT Y C+ GY L G +CT G WT P C
Sbjct: 413 PPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQC 466
Score = 36.3 bits (80), Expect = 0.60
Identities = 19/61 (31%), Positives = 28/61 (45%), Gaps = 4/61 (6%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTL----RGDWTLEPPF 57
C P V N + + EN + G YECD+G+ L G ++ +C G W+ P
Sbjct: 719 CHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQ 778
Query: 58 C 58
C
Sbjct: 779 C 779
Score = 34.7 bits (76), Expect = 1.8
Identities = 16/58 (27%), Positives = 26/58 (44%), Gaps = 1/58 (1%)
Query: 1 RCGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
+C HP + VS + T+ ++ C G+ L G++Q C +G W P C
Sbjct: 350 QCPHPQILRGRMVSGQKDRYTYNDTV-IFACMFGFTLKGSKQIRCNAQGTWEPSAPVC 406
>AL691452-9|CAI16731.1| 971|Homo sapiens complement component
(3d/Epstein Barr virus) receptor 2 protein.
Length = 971
Score = 226 bits (552), Expect = 4e-58
Identities = 182/642 (28%), Positives = 265/642 (41%), Gaps = 89/642 (13%)
Query: 372 GSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRTTH 431
G + Y C G++L+G+K +C G WS PP+C+ C L +G V
Sbjct: 176 GLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRV- 234
Query: 432 GARALYSCRENFTLVGNPERTC--GDEGIWDGEAPRCLFDWCPDPPAVSNASVTVN---G 486
G A + C E + L G P C +G+ + P C +CP PP + N N
Sbjct: 235 GVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTKMPVCEEIFCPSPPPILNGRHIGNSLAN 294
Query: 487 HKAGSLASYTC----ENG--HILSGSTSVTCTLG----GAWSGVPPSCKY----VNCGTP 532
GS+ +YTC E G IL G +++ CT+ G WSG P C+ V C P
Sbjct: 295 VSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHP 354
Query: 533 TIHKGSFVL-INGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEP 591
I +G V TY F C + L G++++ CN G W P CE P
Sbjct: 355 QILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKECQAPP 414
Query: 592 EVPSG----GYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCG 647
+ +G +M FD ++I + C G+ L+GE ++ C +G W+ P C+ C
Sbjct: 415 NILNGQKEDRHMVRFD--PGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACE 472
Query: 648 KLPTLPYGTMELLNGTTH--LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIR 705
+LL H + + SC Y+L G V + C W C+EI
Sbjct: 473 AT------GRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEIT 526
Query: 706 CSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKG------YKV 759
C P V N G +L + G V Y C G + +
Sbjct: 527 CPPP--------PVIYNGAHTGSSL----------EDFPYGTTVTYTCNPGPERGVEFSL 568
Query: 760 IGESLSTCEDN----GQWSGTTPTCQY----VDCGNPGRIENG-KVTLPSNATFYGATAF 810
IGES C N G WSG P C+ V C + I NG K++ FY T
Sbjct: 569 IGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHV-HIANGYKISGKEAPYFYNDTVT 627
Query: 811 YQCDENWELEGVIRRMCQENGTWSLEPPICKEITCP---DPSAQIKAGSGLLVVTSTLSI 867
++C + L+G + C+ + TW E P+C++ TC ++ AGS + +V ++
Sbjct: 628 FKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKETCQHVRQSLQELPAGSRVELVNTS--- 684
Query: 868 GGEAHYQCERGYNLKGHQTRTC--ISKGQWNGTVPVCIPIDCRSPGNIENGKIV-ISNGS 924
C+ GY L GH + C G W +P+C I C P I NGK + +
Sbjct: 685 -------CQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAEN 737
Query: 925 TLFGSSVEYYCLSQYQRVGPFLRKCLDD----GRWSGEEPSC 962
L+G+ V Y C + +G +C D G WSG P C
Sbjct: 738 FLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQC 779
Score = 215 bits (524), Expect = 9e-55
Identities = 190/672 (28%), Positives = 277/672 (41%), Gaps = 81/672 (12%)
Query: 352 TCGSPDKLLNTTI--LGNDYDVGSRIVYKCPEGHMLLGDKSRHC----KKDGFWSGAPPS 405
+CGSP +LN I VG+ I Y C L+G+KS C K DG W P
Sbjct: 22 SCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPK 81
Query: 406 CKYVN--CGGLTPIEDGDVALIDNRT-THGARALYSCRENFTLVGNPERTCGDEGIWDG- 461
C+Y N PI G + + HG ++C+ NF++ GN C +W
Sbjct: 82 CEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWGPT 141
Query: 462 EAPRCLFDW---CPDPPAVSNA---SVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGG 515
P C+ + CP P + N S V G +Y+CE+G++L G + C G
Sbjct: 142 RLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSG 201
Query: 516 AWSGVPPSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGK 575
WS VPP+C+ C + V G A F C+ Y L G C G+
Sbjct: 202 KWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQ 261
Query: 576 ---WSYDIPSCELTSCPE-PEVPSGGYM--EAFDYYVHSTINFHCEAGHK------LIGE 623
W+ +P CE CP P + +G ++ + S + + C+ + LIGE
Sbjct: 262 GVAWT-KMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGE 320
Query: 624 PNLVC----QQDGEWSGDSPTCEY----IDCGKLPTLPYGTM--ELLNGTTHLGSVIQYS 673
L C Q+ G WSG +P CE + C P + G M + T+ +VI ++
Sbjct: 321 STLRCTVDSQKTGTWSGPAPRCELSTSAVQCPH-PQILRGRMVSGQKDRYTYNDTVI-FA 378
Query: 674 CTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRT 733
C + L G + C + W S+P CE+ C P +I++ DR ++R
Sbjct: 379 CMFGFTLKGSKQIRCNAQGTWEPSAPVCEK-ECQAP----PNILNGQKEDRH----MVR- 428
Query: 734 SDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIEN 793
+ G +KY C GY ++GE C G W+ P C+ C GR
Sbjct: 429 ---------FDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGR--- 476
Query: 794 GKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIK 853
+T P + F C E ++L G + + CQ W +E +CKEITCP P I
Sbjct: 477 QLLTKPQH-QFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPV-IY 534
Query: 854 AGSGLLVVTSTLSIGGEAHYQC----ERG--YNLKGHQTRTCIS----KGQWNGTVPVC- 902
G+ G Y C ERG ++L G T C S +G W+G P+C
Sbjct: 535 NGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCK 594
Query: 903 ---IPIDCRSPGNIENG-KIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGE 958
+ + C S +I NG KI + +V + C S + G +C D W E
Sbjct: 595 LSLLAVQC-SHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPE 653
Query: 959 EPSCELATNEAV 970
P CE T + V
Sbjct: 654 IPVCEKETCQHV 665
Score = 189 bits (461), Expect = 4e-47
Identities = 168/661 (25%), Positives = 266/661 (40%), Gaps = 93/661 (14%)
Query: 353 CGSPDKLLNTTILGN---DYDVGSRIVYKC---PE---GHMLLGDKSRHC----KKDGFW 399
C SP +LN +GN + GS + Y C PE +L+G+ + C +K G W
Sbjct: 276 CPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTW 335
Query: 400 SGAPPSCKY----VNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGD 455
SG P C+ V C + V+ +R T+ +++C FTL G+ + C
Sbjct: 336 SGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNA 395
Query: 456 EGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKA----GSLASYTCENGHILSGSTSVTC 511
+G W+ AP C + C PP + N + H G+ Y+C G++L G S+ C
Sbjct: 396 QGTWEPSAPVCEKE-CQAPPNILNGQKE-DRHMVRFDPGTSIKYSCNPGYVLVGEESIQC 453
Query: 512 TLGGAWSGVPPSCKYVNC---GTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEEL 568
T G W+ P CK C G + K + +C Y L+G+
Sbjct: 454 TSEGVWTPPVPQCKVAACEATGRQLLTKPQHQFVRPDVNS------SCGEGYKLSGSVYQ 507
Query: 569 VCNRDGKWSYDIPSCELTSCPEPEV-----PSGGYMEAFDYYVHSTINFHCEAGHK---- 619
C W +I C+ +CP P V +G +E F Y +T+ + C G +
Sbjct: 508 ECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPY--GTTVTYTCNPGPERGVE 565
Query: 620 --LIGEPNLVC----QQDGEWSGDSPTCEY----IDCGKLPTLPYGTMELLNGTTHLGSV 669
LIGE + C Q+ G WSG +P C+ + C + +
Sbjct: 566 FSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDT 625
Query: 670 IQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHT 729
+ + C + + L G + C + W P CE+ C +S+ + R
Sbjct: 626 VTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKETCQH---VRQSLQELPAGSRVE--- 679
Query: 730 LIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCED--NGQWSGTTPTCQYVDCGN 787
L+ TS C+ GY++ G + C+D NG W P C+ + C
Sbjct: 680 LVNTS------------------CQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHP 721
Query: 788 PGRIENGKVT-LPSNATFYGATAFYQCDENWELEGVIRRMCQEN----GTWSLEPPICKE 842
P I NGK T + + YG Y+CD+ + L G + C+ + G+WS P C
Sbjct: 722 PPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLR 781
Query: 843 ---IT-CPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGT 898
+T CP+P ++K G L S S + C G+ + G + C + W
Sbjct: 782 SPPVTRCPNP--EVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPG 839
Query: 899 VPVCI--PIDCRSPGNIEN-GKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRW 955
VP CI ++C SP +++ K + +G+ V C Y G +C D +W
Sbjct: 840 VPTCIKKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSDHQW 899
Query: 956 S 956
+
Sbjct: 900 N 900
Score = 178 bits (433), Expect = 1e-43
Identities = 159/612 (25%), Positives = 239/612 (39%), Gaps = 81/612 (13%)
Query: 404 PSCKYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTC----GDEGIW 459
P ++CG PI +G ++ G YSC F L+G C +G W
Sbjct: 16 PGVLGISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTW 75
Query: 460 DGEAPRC----LFDWCPDPPAVSNASVT-VNGHKAGSLASYTCENGHILSGSTSVTCTLG 514
D AP+C + CP+P + ++ G ++ C+ ++G+ SV C
Sbjct: 76 DKPAPKCEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQAN 135
Query: 515 GAWSGVP-PSCKYV---NC-GTPTIHKGSFVLIN-GTTTYGSIAQFTCEPDYWLNGAEEL 568
W P+C V C P IH G N G+ G ++CE Y L G + +
Sbjct: 136 NMWGPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKII 195
Query: 569 VCNRDGKWSYDIPSCELTSCPE-PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLV 627
C GKWS P+CE C P+G E V T NF C+ G++L G P+
Sbjct: 196 NCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSR 255
Query: 628 CQQDGE---WSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHL--GSVIQYSCT------T 676
C G+ W+ P CE I C P + G + N ++ GS++ Y+C
Sbjct: 256 CVIAGQGVAWT-KMPVCEEIFCPSPPPILNG-RHIGNSLANVSYGSIVTYTCDPDPEEGV 313
Query: 677 NYRLVGPVRRTCTEEFQ----WSDSSPRCE----EIRCSDPIVAEKSIVSVTGNDRSHGH 728
N+ L+G CT + Q WS +PRCE ++C P + +VS + ++
Sbjct: 314 NFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYTYND 373
Query: 729 TLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNP 788
T+I + C G+ + G C G W + P C+ +C P
Sbjct: 374 TVI-------------------FACMFGFTLKGSKQIRCNAQGTWEPSAPVCE-KECQAP 413
Query: 789 GRIENGKVTLPSNATFYGATAF-YQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPD 847
I NG+ F T+ Y C+ + L G C G W+ P CK C
Sbjct: 414 PNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACE- 472
Query: 848 PSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDC 907
G LL + + + C GY L G + C W + +C I C
Sbjct: 473 -----ATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITC 527
Query: 908 RSPGNIENGKIVISNGSTL----FGSSVEYYCLS------QYQRVGPFLRKCLDD----G 953
P I NG GS+L +G++V Y C ++ +G +C + G
Sbjct: 528 PPPPVIYNG---AHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERG 584
Query: 954 RWSGEEPSCELA 965
WSG P C+L+
Sbjct: 585 TWSGPAPLCKLS 596
Score = 165 bits (400), Expect = 1e-39
Identities = 137/536 (25%), Positives = 218/536 (40%), Gaps = 68/536 (12%)
Query: 369 YDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNR 428
+D G+ I Y C G++L+G++S C +G W+ P CK C E L+
Sbjct: 429 FDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAAC------EATGRQLLTKP 482
Query: 429 TTHGAR--ALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVT--- 483
R SC E + L G+ + C W E C CP PP + N + T
Sbjct: 483 QHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSS 542
Query: 484 VNGHKAGSLASYTCENG------HILSGSTSVTCTLG----GAWSGVPPSCKY----VNC 529
+ G+ +YTC G L G +++ CT G WSG P CK V C
Sbjct: 543 LEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQC 602
Query: 530 GTPTIHKGSFVLINGTTT---YGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELT 586
+H + I+G Y F C + L G+ ++ C D W +IP CE
Sbjct: 603 SH--VHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKE 660
Query: 587 SCPE-----PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQ--QDGEWSGDSP 639
+C E+P+G +E +N C+ G++L G +CQ ++G W P
Sbjct: 661 TCQHVRQSLQELPAGSRVEL--------VNTSCQDGYQLTGHAYQMCQDAENGIWFKKIP 712
Query: 640 TCEYIDCGKLPTLPYGTMELLNGTTHL-GSVIQYSCTTNYRLVGPVRRTCTEEFQ----W 694
C+ I C P + G + L G+ + Y C + L+G + C + + W
Sbjct: 713 LCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSW 772
Query: 695 SDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCE 754
S SP+C +R S P+ + HG+ L +T + Y +V C
Sbjct: 773 SGPSPQC--LR-SPPVTR------CPNPEVKHGYKLNKTH------SAYSHNDIVYVDCN 817
Query: 755 KGYKVIGESLSTCEDNGQWSGTTPTC--QYVDCGNPGRIENGKVTL-PSNATFYGATAFY 811
G+ + G + C + W PTC + V+C +P ++ + L P YGA
Sbjct: 818 PGFIMNGSRVIRCHTDNTWVPGVPTCIKKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTL 877
Query: 812 QCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSI 867
+C++ + LEG + CQ + W+ +C+ + I AG LL +++
Sbjct: 878 ECEDGYMLEGSPQSQCQSDHQWNPPLAVCRSRSLAPVLCGIAAGLILLTFLIVITL 933
Score = 164 bits (398), Expect = 2e-39
Identities = 150/586 (25%), Positives = 220/586 (37%), Gaps = 66/586 (11%)
Query: 353 CGSPDKLLNTTILGND--YDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVN 410
C P L + G Y +++ C G L G K C G W + P C+
Sbjct: 351 CPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEK-E 409
Query: 411 CGGLTPIEDG---DVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL 467
C I +G D ++ R G YSC + LVG C EG+W P+C
Sbjct: 410 CQAPPNILNGQKEDRHMV--RFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCK 467
Query: 468 FDWCPDPPAVSNASVTVNGHK-AGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKY 526
C A +T H+ + +C G+ LSGS C W CK
Sbjct: 468 VAACE---ATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKE 524
Query: 527 VNCGTP-TIHKGSFVLIN-GTTTYGSIAQFTCEP------DYWLNGAEELVCNRD----G 574
+ C P I+ G+ + YG+ +TC P ++ L G + C + G
Sbjct: 525 ITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERG 584
Query: 575 KWSYDIPSCELT----SCPEPEVPSGGYMEAFD--YYVHSTINFHCEAGHKLIGEPNLVC 628
WS P C+L+ C + +G + + Y+ + T+ F C +G L G + C
Sbjct: 585 TWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRC 644
Query: 629 QQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTC 688
+ D W + P CE C + EL G+ ++ SC Y+L G + C
Sbjct: 645 KADNTWDPEIPVCEKETCQHVRQ---SLQELPAGSRV--ELVNTSCQDGYQLTGHAYQMC 699
Query: 689 --TEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIG 746
E W P C+ I C P V V G HT + ++N GN
Sbjct: 700 QDAENGIWFKKIPLCKVIHCHPPPVI------VNGK-----HTGMM-AENFLYGNE---- 743
Query: 747 ALVKYRCEKGYKVIGESLSTCEDN----GQWSGTTPTC----QYVDCGNPGRIENGKVTL 798
V Y C++G+ ++GE C + G WSG +P C C NP K+
Sbjct: 744 --VSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNK 801
Query: 799 PSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPIC--KEITCPDPSAQIKAGS 856
+A + + C+ + + G C + TW P C KE+ C P+
Sbjct: 802 THSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPTCIKKEVNCSSPADMDGIQK 861
Query: 857 GLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVC 902
GL G +CE GY L+G C S QWN + VC
Sbjct: 862 GL-EPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSDHQWNPPLAVC 906
Score = 38.7 bits (86), Expect = 0.11
Identities = 19/56 (33%), Positives = 25/56 (44%), Gaps = 2/56 (3%)
Query: 5 PAVPP--NARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
PA+P N + N +I G Y C+ GY L G + C G W+ PP C
Sbjct: 155 PALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTC 210
Score = 36.3 bits (80), Expect = 0.60
Identities = 19/54 (35%), Positives = 24/54 (44%), Gaps = 3/54 (5%)
Query: 8 PPNARVSIPNEENIVA---GTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
PPN + ++V GT Y C+ GY L G +CT G WT P C
Sbjct: 413 PPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQC 466
Score = 36.3 bits (80), Expect = 0.60
Identities = 19/61 (31%), Positives = 28/61 (45%), Gaps = 4/61 (6%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTL----RGDWTLEPPF 57
C P V N + + EN + G YECD+G+ L G ++ +C G W+ P
Sbjct: 719 CHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQ 778
Query: 58 C 58
C
Sbjct: 779 C 779
Score = 34.7 bits (76), Expect = 1.8
Identities = 16/58 (27%), Positives = 26/58 (44%), Gaps = 1/58 (1%)
Query: 1 RCGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
+C HP + VS + T+ ++ C G+ L G++Q C +G W P C
Sbjct: 350 QCPHPQILRGRMVSGQKDRYTYNDTV-IFACMFGFTLKGSKQIRCNAQGTWEPSAPVC 406
>AL691452-7|CAI16730.1| 1033|Homo sapiens complement component
(3d/Epstein Barr virus) receptor 2 protein.
Length = 1033
Score = 226 bits (552), Expect = 4e-58
Identities = 182/642 (28%), Positives = 265/642 (41%), Gaps = 89/642 (13%)
Query: 372 GSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRTTH 431
G + Y C G++L+G+K +C G WS PP+C+ C L +G V
Sbjct: 176 GLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRV- 234
Query: 432 GARALYSCRENFTLVGNPERTC--GDEGIWDGEAPRCLFDWCPDPPAVSNASVTVN---G 486
G A + C E + L G P C +G+ + P C +CP PP + N N
Sbjct: 235 GVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTKMPVCEEIFCPSPPPILNGRHIGNSLAN 294
Query: 487 HKAGSLASYTC----ENG--HILSGSTSVTCTLG----GAWSGVPPSCKY----VNCGTP 532
GS+ +YTC E G IL G +++ CT+ G WSG P C+ V C P
Sbjct: 295 VSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHP 354
Query: 533 TIHKGSFVL-INGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEP 591
I +G V TY F C + L G++++ CN G W P CE P
Sbjct: 355 QILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKECQAPP 414
Query: 592 EVPSG----GYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCG 647
+ +G +M FD ++I + C G+ L+GE ++ C +G W+ P C+ C
Sbjct: 415 NILNGQKEDRHMVRFD--PGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACE 472
Query: 648 KLPTLPYGTMELLNGTTH--LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIR 705
+LL H + + SC Y+L G V + C W C+EI
Sbjct: 473 AT------GRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEIT 526
Query: 706 CSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKG------YKV 759
C P V N G +L + G V Y C G + +
Sbjct: 527 CPPP--------PVIYNGAHTGSSL----------EDFPYGTTVTYTCNPGPERGVEFSL 568
Query: 760 IGESLSTCEDN----GQWSGTTPTCQY----VDCGNPGRIENG-KVTLPSNATFYGATAF 810
IGES C N G WSG P C+ V C + I NG K++ FY T
Sbjct: 569 IGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHV-HIANGYKISGKEAPYFYNDTVT 627
Query: 811 YQCDENWELEGVIRRMCQENGTWSLEPPICKEITCP---DPSAQIKAGSGLLVVTSTLSI 867
++C + L+G + C+ + TW E P+C++ TC ++ AGS + +V ++
Sbjct: 628 FKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKETCQHVRQSLQELPAGSRVELVNTS--- 684
Query: 868 GGEAHYQCERGYNLKGHQTRTC--ISKGQWNGTVPVCIPIDCRSPGNIENGKIV-ISNGS 924
C+ GY L GH + C G W +P+C I C P I NGK + +
Sbjct: 685 -------CQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAEN 737
Query: 925 TLFGSSVEYYCLSQYQRVGPFLRKCLDD----GRWSGEEPSC 962
L+G+ V Y C + +G +C D G WSG P C
Sbjct: 738 FLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQC 779
Score = 215 bits (524), Expect = 9e-55
Identities = 190/672 (28%), Positives = 277/672 (41%), Gaps = 81/672 (12%)
Query: 352 TCGSPDKLLNTTI--LGNDYDVGSRIVYKCPEGHMLLGDKSRHC----KKDGFWSGAPPS 405
+CGSP +LN I VG+ I Y C L+G+KS C K DG W P
Sbjct: 22 SCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPK 81
Query: 406 CKYVN--CGGLTPIEDGDVALIDNRT-THGARALYSCRENFTLVGNPERTCGDEGIWDG- 461
C+Y N PI G + + HG ++C+ NF++ GN C +W
Sbjct: 82 CEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWGPT 141
Query: 462 EAPRCLFDW---CPDPPAVSNA---SVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGG 515
P C+ + CP P + N S V G +Y+CE+G++L G + C G
Sbjct: 142 RLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSG 201
Query: 516 AWSGVPPSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGK 575
WS VPP+C+ C + V G A F C+ Y L G C G+
Sbjct: 202 KWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQ 261
Query: 576 ---WSYDIPSCELTSCPE-PEVPSGGYM--EAFDYYVHSTINFHCEAGHK------LIGE 623
W+ +P CE CP P + +G ++ + S + + C+ + LIGE
Sbjct: 262 GVAWT-KMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGE 320
Query: 624 PNLVC----QQDGEWSGDSPTCEY----IDCGKLPTLPYGTM--ELLNGTTHLGSVIQYS 673
L C Q+ G WSG +P CE + C P + G M + T+ +VI ++
Sbjct: 321 STLRCTVDSQKTGTWSGPAPRCELSTSAVQCPH-PQILRGRMVSGQKDRYTYNDTVI-FA 378
Query: 674 CTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRT 733
C + L G + C + W S+P CE+ C P +I++ DR ++R
Sbjct: 379 CMFGFTLKGSKQIRCNAQGTWEPSAPVCEK-ECQAP----PNILNGQKEDRH----MVR- 428
Query: 734 SDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIEN 793
+ G +KY C GY ++GE C G W+ P C+ C GR
Sbjct: 429 ---------FDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGR--- 476
Query: 794 GKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIK 853
+T P + F C E ++L G + + CQ W +E +CKEITCP P I
Sbjct: 477 QLLTKPQH-QFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPV-IY 534
Query: 854 AGSGLLVVTSTLSIGGEAHYQC----ERG--YNLKGHQTRTCIS----KGQWNGTVPVC- 902
G+ G Y C ERG ++L G T C S +G W+G P+C
Sbjct: 535 NGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCK 594
Query: 903 ---IPIDCRSPGNIENG-KIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGE 958
+ + C S +I NG KI + +V + C S + G +C D W E
Sbjct: 595 LSLLAVQC-SHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPE 653
Query: 959 EPSCELATNEAV 970
P CE T + V
Sbjct: 654 IPVCEKETCQHV 665
Score = 201 bits (490), Expect = 1e-50
Identities = 176/669 (26%), Positives = 267/669 (39%), Gaps = 94/669 (14%)
Query: 353 CGSPDKLLNTTILGN---DYDVGSRIVYKC---PE---GHMLLGDKSRHC----KKDGFW 399
C SP +LN +GN + GS + Y C PE +L+G+ + C +K G W
Sbjct: 276 CPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTW 335
Query: 400 SGAPPSCKY----VNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGD 455
SG P C+ V C + V+ +R T+ +++C FTL G+ + C
Sbjct: 336 SGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNA 395
Query: 456 EGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKA----GSLASYTCENGHILSGSTSVTC 511
+G W+ AP C + C PP + N + H G+ Y+C G++L G S+ C
Sbjct: 396 QGTWEPSAPVCEKE-CQAPPNILNGQKE-DRHMVRFDPGTSIKYSCNPGYVLVGEESIQC 453
Query: 512 TLGGAWSGVPPSCKYVNC---GTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEEL 568
T G W+ P CK C G + K + +C Y L+G+
Sbjct: 454 TSEGVWTPPVPQCKVAACEATGRQLLTKPQHQFVRPDVNS------SCGEGYKLSGSVYQ 507
Query: 569 VCNRDGKWSYDIPSCELTSCPEPEV-----PSGGYMEAFDYYVHSTINFHCEAGHK---- 619
C W +I C+ +CP P V +G +E F Y +T+ + C G +
Sbjct: 508 ECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPY--GTTVTYTCNPGPERGVE 565
Query: 620 --LIGEPNLVC----QQDGEWSGDSPTCEY----IDCGKLPTLPYGTMELLNGTTHLGSV 669
LIGE + C Q+ G WSG +P C+ + C + +
Sbjct: 566 FSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDT 625
Query: 670 IQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHT 729
+ + C + + L G + C + W P CE+ C +S+ + R
Sbjct: 626 VTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKETCQH---VRQSLQELPAGSRVE--- 679
Query: 730 LIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCED--NGQWSGTTPTCQYVDCGN 787
L+ TS C+ GY++ G + C+D NG W P C+ + C
Sbjct: 680 LVNTS------------------CQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHP 721
Query: 788 PGRIENGKVT-LPSNATFYGATAFYQCDENWELEGVIRRMCQEN----GTWSLEPPICKE 842
P I NGK T + + YG Y+CD+ + L G + C+ + G+WS P C
Sbjct: 722 PPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLR 781
Query: 843 ---IT-CPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGT 898
+T CP+P ++K G L S S + C G+ + G + C + W
Sbjct: 782 SPPVTRCPNP--EVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPG 839
Query: 899 VPVCIP---IDCRSPGNIENGKIVISNGSTLF-GSSVEYYCLSQYQRVGPFLRKCLDDGR 954
VP CI I C P NG N + G S+ Y C Y VG L C +G
Sbjct: 840 VPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGT 899
Query: 955 WSGEEPSCE 963
WS P C+
Sbjct: 900 WSQPAPHCK 908
Score = 200 bits (487), Expect = 3e-50
Identities = 156/572 (27%), Positives = 231/572 (40%), Gaps = 70/572 (12%)
Query: 369 YDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNR 428
+D G+ I Y C G++L+G++S C +G W+ P CK C E L+
Sbjct: 429 FDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAAC------EATGRQLLTKP 482
Query: 429 TTHGAR--ALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVT--- 483
R SC E + L G+ + C W E C CP PP + N + T
Sbjct: 483 QHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSS 542
Query: 484 VNGHKAGSLASYTCENG------HILSGSTSVTCTLG----GAWSGVPPSCKY----VNC 529
+ G+ +YTC G L G +++ CT G WSG P CK V C
Sbjct: 543 LEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQC 602
Query: 530 GTPTIHKGSFVLINGTTT---YGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELT 586
+H + I+G Y F C + L G+ ++ C D W +IP CE
Sbjct: 603 SH--VHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKE 660
Query: 587 SCPE-----PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQ--QDGEWSGDSP 639
+C E+P+G +E +N C+ G++L G +CQ ++G W P
Sbjct: 661 TCQHVRQSLQELPAGSRVEL--------VNTSCQDGYQLTGHAYQMCQDAENGIWFKKIP 712
Query: 640 TCEYIDCGKLPTLPYGTMELLNGTTHL-GSVIQYSCTTNYRLVGPVRRTCTEEFQ----W 694
C+ I C P + G + L G+ + Y C + L+G + C + + W
Sbjct: 713 LCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSW 772
Query: 695 SDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCE 754
S SP+C +R S P+ + HG+ L +T + Y +V C
Sbjct: 773 SGPSPQC--LR-SPPVTR------CPNPEVKHGYKLNKTH------SAYSHNDIVYVDCN 817
Query: 755 KGYKVIGESLSTCEDNGQWSGTTPTC---QYVDCGNPGRIENGKVTLPSNATFY-GATAF 810
G+ + G + C + W PTC ++ C P + NG T + A F G +
Sbjct: 818 PGFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSIL 877
Query: 811 YQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGE 870
Y CD+ + L G +C GTWS P CKE+ C P+ GL G
Sbjct: 878 YSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVNCSSPADMDGIQKGL-EPRKMYQYGAV 936
Query: 871 AHYQCERGYNLKGHQTRTCISKGQWNGTVPVC 902
+CE GY L+G C S QWN + VC
Sbjct: 937 VTLECEDGYMLEGSPQSQCQSDHQWNPPLAVC 968
Score = 178 bits (433), Expect = 1e-43
Identities = 159/612 (25%), Positives = 239/612 (39%), Gaps = 81/612 (13%)
Query: 404 PSCKYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTC----GDEGIW 459
P ++CG PI +G ++ G YSC F L+G C +G W
Sbjct: 16 PGVLGISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTW 75
Query: 460 DGEAPRC----LFDWCPDPPAVSNASVT-VNGHKAGSLASYTCENGHILSGSTSVTCTLG 514
D AP+C + CP+P + ++ G ++ C+ ++G+ SV C
Sbjct: 76 DKPAPKCEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQAN 135
Query: 515 GAWSGVP-PSCKYV---NC-GTPTIHKGSFVLIN-GTTTYGSIAQFTCEPDYWLNGAEEL 568
W P+C V C P IH G N G+ G ++CE Y L G + +
Sbjct: 136 NMWGPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKII 195
Query: 569 VCNRDGKWSYDIPSCELTSCPE-PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLV 627
C GKWS P+CE C P+G E V T NF C+ G++L G P+
Sbjct: 196 NCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSR 255
Query: 628 CQQDGE---WSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHL--GSVIQYSCT------T 676
C G+ W+ P CE I C P + G + N ++ GS++ Y+C
Sbjct: 256 CVIAGQGVAWT-KMPVCEEIFCPSPPPILNG-RHIGNSLANVSYGSIVTYTCDPDPEEGV 313
Query: 677 NYRLVGPVRRTCTEEFQ----WSDSSPRCE----EIRCSDPIVAEKSIVSVTGNDRSHGH 728
N+ L+G CT + Q WS +PRCE ++C P + +VS + ++
Sbjct: 314 NFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYTYND 373
Query: 729 TLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNP 788
T+I + C G+ + G C G W + P C+ +C P
Sbjct: 374 TVI-------------------FACMFGFTLKGSKQIRCNAQGTWEPSAPVCE-KECQAP 413
Query: 789 GRIENGKVTLPSNATFYGATAF-YQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPD 847
I NG+ F T+ Y C+ + L G C G W+ P CK C
Sbjct: 414 PNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACE- 472
Query: 848 PSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDC 907
G LL + + + C GY L G + C W + +C I C
Sbjct: 473 -----ATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITC 527
Query: 908 RSPGNIENGKIVISNGSTL----FGSSVEYYCLS------QYQRVGPFLRKCLDD----G 953
P I NG GS+L +G++V Y C ++ +G +C + G
Sbjct: 528 PPPPVIYNG---AHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERG 584
Query: 954 RWSGEEPSCELA 965
WSG P C+L+
Sbjct: 585 TWSGPAPLCKLS 596
Score = 173 bits (421), Expect = 3e-42
Identities = 160/642 (24%), Positives = 244/642 (38%), Gaps = 68/642 (10%)
Query: 353 CGSPDKLLNTTILGND--YDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVN 410
C P L + G Y +++ C G L G K C G W + P C+
Sbjct: 351 CPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEK-E 409
Query: 411 CGGLTPIEDG---DVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL 467
C I +G D ++ R G YSC + LVG C EG+W P+C
Sbjct: 410 CQAPPNILNGQKEDRHMV--RFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCK 467
Query: 468 FDWCPDPPAVSNASVTVNGHK-AGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKY 526
C A +T H+ + +C G+ LSGS C W CK
Sbjct: 468 VAACE---ATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKE 524
Query: 527 VNCGTP-TIHKGSFVLIN-GTTTYGSIAQFTCEP------DYWLNGAEELVCNRD----G 574
+ C P I+ G+ + YG+ +TC P ++ L G + C + G
Sbjct: 525 ITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERG 584
Query: 575 KWSYDIPSCELT----SCPEPEVPSGGYMEAFD--YYVHSTINFHCEAGHKLIGEPNLVC 628
WS P C+L+ C + +G + + Y+ + T+ F C +G L G + C
Sbjct: 585 TWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRC 644
Query: 629 QQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTC 688
+ D W + P CE C + EL G+ ++ SC Y+L G + C
Sbjct: 645 KADNTWDPEIPVCEKETCQHVRQ---SLQELPAGSRV--ELVNTSCQDGYQLTGHAYQMC 699
Query: 689 --TEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIG 746
E W P C+ I C P V V G HT + ++N GN
Sbjct: 700 QDAENGIWFKKIPLCKVIHCHPPPVI------VNGK-----HTGMM-AENFLYGNE---- 743
Query: 747 ALVKYRCEKGYKVIGESLSTCEDN----GQWSGTTPTC----QYVDCGNPGRIENGKVTL 798
V Y C++G+ ++GE C + G WSG +P C C NP K+
Sbjct: 744 --VSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNK 801
Query: 799 PSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKE---ITCPDPSAQIKAG 855
+A + + C+ + + G C + TW P C + I CP P + G
Sbjct: 802 THSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPP-KTPNG 860
Query: 856 SGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIEN 915
+ + S G Y C++GY L G C +G W+ P C ++C SP +++
Sbjct: 861 NHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVNCSSPADMDG 920
Query: 916 -GKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWS 956
K + +G+ V C Y G +C D +W+
Sbjct: 921 IQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSDHQWN 962
Score = 152 bits (369), Expect = 6e-36
Identities = 123/465 (26%), Positives = 182/465 (39%), Gaps = 56/465 (12%)
Query: 352 TCGSPDKLLNTTILGN---DYDVGSRIVYKCPEG------HMLLGDKSRHCKKD----GF 398
TC P + N G+ D+ G+ + Y C G L+G+ + C + G
Sbjct: 526 TCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGT 585
Query: 399 WSGAPPSCKY----VNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCG 454
WSG P CK V C + ++ + + + C FTL G+ + C
Sbjct: 586 WSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCK 645
Query: 455 DEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTC--T 512
+ WD E P C + C V + + L + +C++G+ L+G C
Sbjct: 646 ADNTWDPEIPVCEKETCQH---VRQSLQELPAGSRVELVNTSCQDGYQLTGHAYQMCQDA 702
Query: 513 LGGAWSGVPPSCKYVNCGTP-TIHKGSFV-LINGTTTYGSIAQFTCEPDYWLNGAEELVC 570
G W P CK ++C P I G ++ YG+ + C+ ++L G ++L C
Sbjct: 703 ENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQC 762
Query: 571 NRD----GKWSYDIPSC----ELTSCPEPEVPSGGYM-EAFDYYVHSTINF-HCEAGHKL 620
D G WS P C +T CP PEV G + + Y H+ I + C G +
Sbjct: 763 RSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIM 822
Query: 621 IGEPNLVCQQDGEWSGDSPTC---EYIDCGKLPTLPYGTMELLN-GTTHLGSVIQYSCTT 676
G + C D W PTC +I C P P G N G I YSC
Sbjct: 823 NGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQ 882
Query: 677 NYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDN 736
Y LVG CT E WS +P C+E+ CS P + G +
Sbjct: 883 GYLLVGEALLLCTHEGTWSQPAPHCKEVNCSSP-------ADMDGIQK-----------G 924
Query: 737 RDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQ 781
+ Y+ GA+V CE GY + G S C+ + QW+ C+
Sbjct: 925 LEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSDHQWNPPLAVCR 969
Score = 137 bits (332), Expect = 2e-31
Identities = 129/528 (24%), Positives = 205/528 (38%), Gaps = 66/528 (12%)
Query: 379 CPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDG-DVALIDNRTTHGARALY 437
C EG+ L G + C+ W CK + C I +G +G Y
Sbjct: 495 CGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTY 554
Query: 438 SCREN------FTLVGNPERTCG----DEGIWDGEAPRCLFDWCPDPPAVSNASVTV-NG 486
+C F+L+G C + G W G AP C AV + V + NG
Sbjct: 555 TCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLL----AVQCSHVHIANG 610
Query: 487 HK-AGSLASY--------TCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTIHKG 537
+K +G A Y C +G L GS+ + C W P C+ C + +
Sbjct: 611 YKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKETC--QHVRQS 668
Query: 538 SFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCN--RDGKWSYDIPSCELTSC-PEPEVP 594
L G+ + +C+ Y L G +C +G W IP C++ C P P +
Sbjct: 669 LQELPAGSRV--ELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIV 726
Query: 595 SGGY--MEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQD----GEWSGDSPTC----EYI 644
+G + M A ++ + +++ C+ G L+GE L C+ D G WSG SP C
Sbjct: 727 NGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVT 786
Query: 645 DCGKLPTLPYG-TMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEE 703
C P + +G + + ++ C + + G C + W P C +
Sbjct: 787 RCPN-PEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPTCIK 845
Query: 704 ---IRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVI 760
I C P T N G + R S G + Y C++GY ++
Sbjct: 846 KAFIGCPPP--------PKTPNGNHTGGNIARFSP----------GMSILYSCDQGYLLV 887
Query: 761 GESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTL-PSNATFYGATAFYQCDENWEL 819
GE+L C G WS P C+ V+C +P ++ + L P YGA +C++ + L
Sbjct: 888 GEALLLCTHEGTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYML 947
Query: 820 EGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSI 867
EG + CQ + W+ +C+ + I AG LL +++
Sbjct: 948 EGSPQSQCQSDHQWNPPLAVCRSRSLAPVLCGIAAGLILLTFLIVITL 995
Score = 108 bits (259), Expect = 1e-22
Identities = 71/256 (27%), Positives = 106/256 (41%), Gaps = 23/256 (8%)
Query: 353 CGSPDKLLN---TTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKD----GFWSGAPPS 405
C P ++N T ++ ++ G+ + Y+C +G LLG+K C+ D G WSG P
Sbjct: 719 CHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQ 778
Query: 406 CKYVNCGGLTPIEDGDVALIDNRT----THGARALYSCRENFTLVGNPERTCGDEGIWDG 461
C P + N+T +H C F + G+ C + W
Sbjct: 779 CLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVP 838
Query: 462 EAPRCL---FDWCPDPPAVSNASVT---VNGHKAGSLASYTCENGHILSGSTSVTCTLGG 515
P C+ F CP PP N + T + G Y+C+ G++L G + CT G
Sbjct: 839 GVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEG 898
Query: 516 AWSGVPPSCKYVNCGTPT----IHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCN 571
WS P CK VNC +P I KG + YG++ CE Y L G+ + C
Sbjct: 899 TWSQPAPHCKEVNCSSPADMDGIQKG--LEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQ 956
Query: 572 RDGKWSYDIPSCELTS 587
D +W+ + C S
Sbjct: 957 SDHQWNPPLAVCRSRS 972
Score = 40.3 bits (90), Expect = 0.037
Identities = 23/75 (30%), Positives = 29/75 (38%), Gaps = 1/75 (1%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTN 61
C P PN + N G +Y CD+GY L G CT G W+ P C
Sbjct: 851 CPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHC-KE 909
Query: 62 VAFRKPANQSTTVRG 76
V PA+ +G
Sbjct: 910 VNCSSPADMDGIQKG 924
Score = 38.7 bits (86), Expect = 0.11
Identities = 19/56 (33%), Positives = 25/56 (44%), Gaps = 2/56 (3%)
Query: 5 PAVPP--NARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
PA+P N + N +I G Y C+ GY L G + C G W+ PP C
Sbjct: 155 PALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTC 210
Score = 36.3 bits (80), Expect = 0.60
Identities = 19/54 (35%), Positives = 24/54 (44%), Gaps = 3/54 (5%)
Query: 8 PPNARVSIPNEENIVA---GTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
PPN + ++V GT Y C+ GY L G +CT G WT P C
Sbjct: 413 PPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQC 466
Score = 36.3 bits (80), Expect = 0.60
Identities = 19/61 (31%), Positives = 28/61 (45%), Gaps = 4/61 (6%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTL----RGDWTLEPPF 57
C P V N + + EN + G YECD+G+ L G ++ +C G W+ P
Sbjct: 719 CHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQ 778
Query: 58 C 58
C
Sbjct: 779 C 779
Score = 34.7 bits (76), Expect = 1.8
Identities = 16/58 (27%), Positives = 26/58 (44%), Gaps = 1/58 (1%)
Query: 1 RCGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
+C HP + VS + T+ ++ C G+ L G++Q C +G W P C
Sbjct: 350 QCPHPQILRGRMVSGQKDRYTYNDTV-IFACMFGFTLKGSKQIRCNAQGTWEPSAPVC 406
>AL391597-7|CAH72949.1| 1033|Homo sapiens complement component
(3d/Epstein Barr virus) receptor 2 protein.
Length = 1033
Score = 226 bits (552), Expect = 4e-58
Identities = 182/642 (28%), Positives = 265/642 (41%), Gaps = 89/642 (13%)
Query: 372 GSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRTTH 431
G + Y C G++L+G+K +C G WS PP+C+ C L +G V
Sbjct: 176 GLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRV- 234
Query: 432 GARALYSCRENFTLVGNPERTC--GDEGIWDGEAPRCLFDWCPDPPAVSNASVTVN---G 486
G A + C E + L G P C +G+ + P C +CP PP + N N
Sbjct: 235 GVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTKMPVCEEIFCPSPPPILNGRHIGNSLAN 294
Query: 487 HKAGSLASYTC----ENG--HILSGSTSVTCTLG----GAWSGVPPSCKY----VNCGTP 532
GS+ +YTC E G IL G +++ CT+ G WSG P C+ V C P
Sbjct: 295 VSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHP 354
Query: 533 TIHKGSFVL-INGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEP 591
I +G V TY F C + L G++++ CN G W P CE P
Sbjct: 355 QILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKECQAPP 414
Query: 592 EVPSG----GYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCG 647
+ +G +M FD ++I + C G+ L+GE ++ C +G W+ P C+ C
Sbjct: 415 NILNGQKEDRHMVRFD--PGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACE 472
Query: 648 KLPTLPYGTMELLNGTTH--LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIR 705
+LL H + + SC Y+L G V + C W C+EI
Sbjct: 473 AT------GRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEIT 526
Query: 706 CSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKG------YKV 759
C P V N G +L + G V Y C G + +
Sbjct: 527 CPPP--------PVIYNGAHTGSSL----------EDFPYGTTVTYTCNPGPERGVEFSL 568
Query: 760 IGESLSTCEDN----GQWSGTTPTCQY----VDCGNPGRIENG-KVTLPSNATFYGATAF 810
IGES C N G WSG P C+ V C + I NG K++ FY T
Sbjct: 569 IGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHV-HIANGYKISGKEAPYFYNDTVT 627
Query: 811 YQCDENWELEGVIRRMCQENGTWSLEPPICKEITCP---DPSAQIKAGSGLLVVTSTLSI 867
++C + L+G + C+ + TW E P+C++ TC ++ AGS + +V ++
Sbjct: 628 FKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKETCQHVRQSLQELPAGSRVELVNTS--- 684
Query: 868 GGEAHYQCERGYNLKGHQTRTC--ISKGQWNGTVPVCIPIDCRSPGNIENGKIV-ISNGS 924
C+ GY L GH + C G W +P+C I C P I NGK + +
Sbjct: 685 -------CQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAEN 737
Query: 925 TLFGSSVEYYCLSQYQRVGPFLRKCLDD----GRWSGEEPSC 962
L+G+ V Y C + +G +C D G WSG P C
Sbjct: 738 FLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQC 779
Score = 215 bits (524), Expect = 9e-55
Identities = 190/672 (28%), Positives = 277/672 (41%), Gaps = 81/672 (12%)
Query: 352 TCGSPDKLLNTTI--LGNDYDVGSRIVYKCPEGHMLLGDKSRHC----KKDGFWSGAPPS 405
+CGSP +LN I VG+ I Y C L+G+KS C K DG W P
Sbjct: 22 SCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPK 81
Query: 406 CKYVN--CGGLTPIEDGDVALIDNRT-THGARALYSCRENFTLVGNPERTCGDEGIWDG- 461
C+Y N PI G + + HG ++C+ NF++ GN C +W
Sbjct: 82 CEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWGPT 141
Query: 462 EAPRCLFDW---CPDPPAVSNA---SVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGG 515
P C+ + CP P + N S V G +Y+CE+G++L G + C G
Sbjct: 142 RLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSG 201
Query: 516 AWSGVPPSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGK 575
WS VPP+C+ C + V G A F C+ Y L G C G+
Sbjct: 202 KWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQ 261
Query: 576 ---WSYDIPSCELTSCPE-PEVPSGGYM--EAFDYYVHSTINFHCEAGHK------LIGE 623
W+ +P CE CP P + +G ++ + S + + C+ + LIGE
Sbjct: 262 GVAWT-KMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGE 320
Query: 624 PNLVC----QQDGEWSGDSPTCEY----IDCGKLPTLPYGTM--ELLNGTTHLGSVIQYS 673
L C Q+ G WSG +P CE + C P + G M + T+ +VI ++
Sbjct: 321 STLRCTVDSQKTGTWSGPAPRCELSTSAVQCPH-PQILRGRMVSGQKDRYTYNDTVI-FA 378
Query: 674 CTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRT 733
C + L G + C + W S+P CE+ C P +I++ DR ++R
Sbjct: 379 CMFGFTLKGSKQIRCNAQGTWEPSAPVCEK-ECQAP----PNILNGQKEDRH----MVR- 428
Query: 734 SDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIEN 793
+ G +KY C GY ++GE C G W+ P C+ C GR
Sbjct: 429 ---------FDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGR--- 476
Query: 794 GKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIK 853
+T P + F C E ++L G + + CQ W +E +CKEITCP P I
Sbjct: 477 QLLTKPQH-QFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPV-IY 534
Query: 854 AGSGLLVVTSTLSIGGEAHYQC----ERG--YNLKGHQTRTCIS----KGQWNGTVPVC- 902
G+ G Y C ERG ++L G T C S +G W+G P+C
Sbjct: 535 NGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCK 594
Query: 903 ---IPIDCRSPGNIENG-KIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGE 958
+ + C S +I NG KI + +V + C S + G +C D W E
Sbjct: 595 LSLLAVQC-SHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPE 653
Query: 959 EPSCELATNEAV 970
P CE T + V
Sbjct: 654 IPVCEKETCQHV 665
Score = 201 bits (490), Expect = 1e-50
Identities = 176/669 (26%), Positives = 267/669 (39%), Gaps = 94/669 (14%)
Query: 353 CGSPDKLLNTTILGN---DYDVGSRIVYKC---PE---GHMLLGDKSRHC----KKDGFW 399
C SP +LN +GN + GS + Y C PE +L+G+ + C +K G W
Sbjct: 276 CPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTW 335
Query: 400 SGAPPSCKY----VNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGD 455
SG P C+ V C + V+ +R T+ +++C FTL G+ + C
Sbjct: 336 SGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNA 395
Query: 456 EGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKA----GSLASYTCENGHILSGSTSVTC 511
+G W+ AP C + C PP + N + H G+ Y+C G++L G S+ C
Sbjct: 396 QGTWEPSAPVCEKE-CQAPPNILNGQKE-DRHMVRFDPGTSIKYSCNPGYVLVGEESIQC 453
Query: 512 TLGGAWSGVPPSCKYVNC---GTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEEL 568
T G W+ P CK C G + K + +C Y L+G+
Sbjct: 454 TSEGVWTPPVPQCKVAACEATGRQLLTKPQHQFVRPDVNS------SCGEGYKLSGSVYQ 507
Query: 569 VCNRDGKWSYDIPSCELTSCPEPEV-----PSGGYMEAFDYYVHSTINFHCEAGHK---- 619
C W +I C+ +CP P V +G +E F Y +T+ + C G +
Sbjct: 508 ECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPY--GTTVTYTCNPGPERGVE 565
Query: 620 --LIGEPNLVC----QQDGEWSGDSPTCEY----IDCGKLPTLPYGTMELLNGTTHLGSV 669
LIGE + C Q+ G WSG +P C+ + C + +
Sbjct: 566 FSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDT 625
Query: 670 IQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHT 729
+ + C + + L G + C + W P CE+ C +S+ + R
Sbjct: 626 VTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKETCQH---VRQSLQELPAGSRVE--- 679
Query: 730 LIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCED--NGQWSGTTPTCQYVDCGN 787
L+ TS C+ GY++ G + C+D NG W P C+ + C
Sbjct: 680 LVNTS------------------CQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHP 721
Query: 788 PGRIENGKVT-LPSNATFYGATAFYQCDENWELEGVIRRMCQEN----GTWSLEPPICKE 842
P I NGK T + + YG Y+CD+ + L G + C+ + G+WS P C
Sbjct: 722 PPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLR 781
Query: 843 ---IT-CPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGT 898
+T CP+P ++K G L S S + C G+ + G + C + W
Sbjct: 782 SPPVTRCPNP--EVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPG 839
Query: 899 VPVCIP---IDCRSPGNIENGKIVISNGSTLF-GSSVEYYCLSQYQRVGPFLRKCLDDGR 954
VP CI I C P NG N + G S+ Y C Y VG L C +G
Sbjct: 840 VPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGT 899
Query: 955 WSGEEPSCE 963
WS P C+
Sbjct: 900 WSQPAPHCK 908
Score = 200 bits (487), Expect = 3e-50
Identities = 156/572 (27%), Positives = 231/572 (40%), Gaps = 70/572 (12%)
Query: 369 YDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNR 428
+D G+ I Y C G++L+G++S C +G W+ P CK C E L+
Sbjct: 429 FDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAAC------EATGRQLLTKP 482
Query: 429 TTHGAR--ALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVT--- 483
R SC E + L G+ + C W E C CP PP + N + T
Sbjct: 483 QHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSS 542
Query: 484 VNGHKAGSLASYTCENG------HILSGSTSVTCTLG----GAWSGVPPSCKY----VNC 529
+ G+ +YTC G L G +++ CT G WSG P CK V C
Sbjct: 543 LEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQC 602
Query: 530 GTPTIHKGSFVLINGTTT---YGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELT 586
+H + I+G Y F C + L G+ ++ C D W +IP CE
Sbjct: 603 SH--VHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKE 660
Query: 587 SCPE-----PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQ--QDGEWSGDSP 639
+C E+P+G +E +N C+ G++L G +CQ ++G W P
Sbjct: 661 TCQHVRQSLQELPAGSRVEL--------VNTSCQDGYQLTGHAYQMCQDAENGIWFKKIP 712
Query: 640 TCEYIDCGKLPTLPYGTMELLNGTTHL-GSVIQYSCTTNYRLVGPVRRTCTEEFQ----W 694
C+ I C P + G + L G+ + Y C + L+G + C + + W
Sbjct: 713 LCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSW 772
Query: 695 SDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCE 754
S SP+C +R S P+ + HG+ L +T + Y +V C
Sbjct: 773 SGPSPQC--LR-SPPVTR------CPNPEVKHGYKLNKTH------SAYSHNDIVYVDCN 817
Query: 755 KGYKVIGESLSTCEDNGQWSGTTPTC---QYVDCGNPGRIENGKVTLPSNATFY-GATAF 810
G+ + G + C + W PTC ++ C P + NG T + A F G +
Sbjct: 818 PGFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSIL 877
Query: 811 YQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGE 870
Y CD+ + L G +C GTWS P CKE+ C P+ GL G
Sbjct: 878 YSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVNCSSPADMDGIQKGL-EPRKMYQYGAV 936
Query: 871 AHYQCERGYNLKGHQTRTCISKGQWNGTVPVC 902
+CE GY L+G C S QWN + VC
Sbjct: 937 VTLECEDGYMLEGSPQSQCQSDHQWNPPLAVC 968
Score = 178 bits (433), Expect = 1e-43
Identities = 159/612 (25%), Positives = 239/612 (39%), Gaps = 81/612 (13%)
Query: 404 PSCKYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTC----GDEGIW 459
P ++CG PI +G ++ G YSC F L+G C +G W
Sbjct: 16 PGVLGISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTW 75
Query: 460 DGEAPRC----LFDWCPDPPAVSNASVT-VNGHKAGSLASYTCENGHILSGSTSVTCTLG 514
D AP+C + CP+P + ++ G ++ C+ ++G+ SV C
Sbjct: 76 DKPAPKCEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQAN 135
Query: 515 GAWSGVP-PSCKYV---NC-GTPTIHKGSFVLIN-GTTTYGSIAQFTCEPDYWLNGAEEL 568
W P+C V C P IH G N G+ G ++CE Y L G + +
Sbjct: 136 NMWGPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKII 195
Query: 569 VCNRDGKWSYDIPSCELTSCPE-PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLV 627
C GKWS P+CE C P+G E V T NF C+ G++L G P+
Sbjct: 196 NCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSR 255
Query: 628 CQQDGE---WSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHL--GSVIQYSCT------T 676
C G+ W+ P CE I C P + G + N ++ GS++ Y+C
Sbjct: 256 CVIAGQGVAWT-KMPVCEEIFCPSPPPILNG-RHIGNSLANVSYGSIVTYTCDPDPEEGV 313
Query: 677 NYRLVGPVRRTCTEEFQ----WSDSSPRCE----EIRCSDPIVAEKSIVSVTGNDRSHGH 728
N+ L+G CT + Q WS +PRCE ++C P + +VS + ++
Sbjct: 314 NFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYTYND 373
Query: 729 TLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNP 788
T+I + C G+ + G C G W + P C+ +C P
Sbjct: 374 TVI-------------------FACMFGFTLKGSKQIRCNAQGTWEPSAPVCE-KECQAP 413
Query: 789 GRIENGKVTLPSNATFYGATAF-YQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPD 847
I NG+ F T+ Y C+ + L G C G W+ P CK C
Sbjct: 414 PNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACE- 472
Query: 848 PSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDC 907
G LL + + + C GY L G + C W + +C I C
Sbjct: 473 -----ATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITC 527
Query: 908 RSPGNIENGKIVISNGSTL----FGSSVEYYCLS------QYQRVGPFLRKCLDD----G 953
P I NG GS+L +G++V Y C ++ +G +C + G
Sbjct: 528 PPPPVIYNG---AHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERG 584
Query: 954 RWSGEEPSCELA 965
WSG P C+L+
Sbjct: 585 TWSGPAPLCKLS 596
Score = 173 bits (421), Expect = 3e-42
Identities = 160/642 (24%), Positives = 244/642 (38%), Gaps = 68/642 (10%)
Query: 353 CGSPDKLLNTTILGND--YDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVN 410
C P L + G Y +++ C G L G K C G W + P C+
Sbjct: 351 CPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEK-E 409
Query: 411 CGGLTPIEDG---DVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL 467
C I +G D ++ R G YSC + LVG C EG+W P+C
Sbjct: 410 CQAPPNILNGQKEDRHMV--RFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCK 467
Query: 468 FDWCPDPPAVSNASVTVNGHK-AGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKY 526
C A +T H+ + +C G+ LSGS C W CK
Sbjct: 468 VAACE---ATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKE 524
Query: 527 VNCGTP-TIHKGSFVLIN-GTTTYGSIAQFTCEP------DYWLNGAEELVCNRD----G 574
+ C P I+ G+ + YG+ +TC P ++ L G + C + G
Sbjct: 525 ITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERG 584
Query: 575 KWSYDIPSCELT----SCPEPEVPSGGYMEAFD--YYVHSTINFHCEAGHKLIGEPNLVC 628
WS P C+L+ C + +G + + Y+ + T+ F C +G L G + C
Sbjct: 585 TWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRC 644
Query: 629 QQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTC 688
+ D W + P CE C + EL G+ ++ SC Y+L G + C
Sbjct: 645 KADNTWDPEIPVCEKETCQHVRQ---SLQELPAGSRV--ELVNTSCQDGYQLTGHAYQMC 699
Query: 689 --TEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIG 746
E W P C+ I C P V V G HT + ++N GN
Sbjct: 700 QDAENGIWFKKIPLCKVIHCHPPPVI------VNGK-----HTGMM-AENFLYGNE---- 743
Query: 747 ALVKYRCEKGYKVIGESLSTCEDN----GQWSGTTPTC----QYVDCGNPGRIENGKVTL 798
V Y C++G+ ++GE C + G WSG +P C C NP K+
Sbjct: 744 --VSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNK 801
Query: 799 PSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKE---ITCPDPSAQIKAG 855
+A + + C+ + + G C + TW P C + I CP P + G
Sbjct: 802 THSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPP-KTPNG 860
Query: 856 SGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIEN 915
+ + S G Y C++GY L G C +G W+ P C ++C SP +++
Sbjct: 861 NHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVNCSSPADMDG 920
Query: 916 -GKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWS 956
K + +G+ V C Y G +C D +W+
Sbjct: 921 IQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSDHQWN 962
Score = 152 bits (369), Expect = 6e-36
Identities = 123/465 (26%), Positives = 182/465 (39%), Gaps = 56/465 (12%)
Query: 352 TCGSPDKLLNTTILGN---DYDVGSRIVYKCPEG------HMLLGDKSRHCKKD----GF 398
TC P + N G+ D+ G+ + Y C G L+G+ + C + G
Sbjct: 526 TCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGT 585
Query: 399 WSGAPPSCKY----VNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCG 454
WSG P CK V C + ++ + + + C FTL G+ + C
Sbjct: 586 WSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCK 645
Query: 455 DEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTC--T 512
+ WD E P C + C V + + L + +C++G+ L+G C
Sbjct: 646 ADNTWDPEIPVCEKETCQH---VRQSLQELPAGSRVELVNTSCQDGYQLTGHAYQMCQDA 702
Query: 513 LGGAWSGVPPSCKYVNCGTP-TIHKGSFV-LINGTTTYGSIAQFTCEPDYWLNGAEELVC 570
G W P CK ++C P I G ++ YG+ + C+ ++L G ++L C
Sbjct: 703 ENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQC 762
Query: 571 NRD----GKWSYDIPSC----ELTSCPEPEVPSGGYM-EAFDYYVHSTINF-HCEAGHKL 620
D G WS P C +T CP PEV G + + Y H+ I + C G +
Sbjct: 763 RSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIM 822
Query: 621 IGEPNLVCQQDGEWSGDSPTC---EYIDCGKLPTLPYGTMELLN-GTTHLGSVIQYSCTT 676
G + C D W PTC +I C P P G N G I YSC
Sbjct: 823 NGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQ 882
Query: 677 NYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDN 736
Y LVG CT E WS +P C+E+ CS P + G +
Sbjct: 883 GYLLVGEALLLCTHEGTWSQPAPHCKEVNCSSP-------ADMDGIQK-----------G 924
Query: 737 RDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQ 781
+ Y+ GA+V CE GY + G S C+ + QW+ C+
Sbjct: 925 LEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSDHQWNPPLAVCR 969
Score = 137 bits (332), Expect = 2e-31
Identities = 129/528 (24%), Positives = 205/528 (38%), Gaps = 66/528 (12%)
Query: 379 CPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDG-DVALIDNRTTHGARALY 437
C EG+ L G + C+ W CK + C I +G +G Y
Sbjct: 495 CGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTY 554
Query: 438 SCREN------FTLVGNPERTCG----DEGIWDGEAPRCLFDWCPDPPAVSNASVTV-NG 486
+C F+L+G C + G W G AP C AV + V + NG
Sbjct: 555 TCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLL----AVQCSHVHIANG 610
Query: 487 HK-AGSLASY--------TCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTIHKG 537
+K +G A Y C +G L GS+ + C W P C+ C + +
Sbjct: 611 YKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKETC--QHVRQS 668
Query: 538 SFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCN--RDGKWSYDIPSCELTSC-PEPEVP 594
L G+ + +C+ Y L G +C +G W IP C++ C P P +
Sbjct: 669 LQELPAGSRV--ELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIV 726
Query: 595 SGGY--MEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQD----GEWSGDSPTC----EYI 644
+G + M A ++ + +++ C+ G L+GE L C+ D G WSG SP C
Sbjct: 727 NGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVT 786
Query: 645 DCGKLPTLPYG-TMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEE 703
C P + +G + + ++ C + + G C + W P C +
Sbjct: 787 RCPN-PEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPTCIK 845
Query: 704 ---IRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVI 760
I C P T N G + R S G + Y C++GY ++
Sbjct: 846 KAFIGCPPP--------PKTPNGNHTGGNIARFSP----------GMSILYSCDQGYLLV 887
Query: 761 GESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTL-PSNATFYGATAFYQCDENWEL 819
GE+L C G WS P C+ V+C +P ++ + L P YGA +C++ + L
Sbjct: 888 GEALLLCTHEGTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYML 947
Query: 820 EGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSI 867
EG + CQ + W+ +C+ + I AG LL +++
Sbjct: 948 EGSPQSQCQSDHQWNPPLAVCRSRSLAPVLCGIAAGLILLTFLIVITL 995
Score = 108 bits (259), Expect = 1e-22
Identities = 71/256 (27%), Positives = 106/256 (41%), Gaps = 23/256 (8%)
Query: 353 CGSPDKLLN---TTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKD----GFWSGAPPS 405
C P ++N T ++ ++ G+ + Y+C +G LLG+K C+ D G WSG P
Sbjct: 719 CHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQ 778
Query: 406 CKYVNCGGLTPIEDGDVALIDNRT----THGARALYSCRENFTLVGNPERTCGDEGIWDG 461
C P + N+T +H C F + G+ C + W
Sbjct: 779 CLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVP 838
Query: 462 EAPRCL---FDWCPDPPAVSNASVT---VNGHKAGSLASYTCENGHILSGSTSVTCTLGG 515
P C+ F CP PP N + T + G Y+C+ G++L G + CT G
Sbjct: 839 GVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEG 898
Query: 516 AWSGVPPSCKYVNCGTPT----IHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCN 571
WS P CK VNC +P I KG + YG++ CE Y L G+ + C
Sbjct: 899 TWSQPAPHCKEVNCSSPADMDGIQKG--LEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQ 956
Query: 572 RDGKWSYDIPSCELTS 587
D +W+ + C S
Sbjct: 957 SDHQWNPPLAVCRSRS 972
Score = 40.3 bits (90), Expect = 0.037
Identities = 23/75 (30%), Positives = 29/75 (38%), Gaps = 1/75 (1%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTN 61
C P PN + N G +Y CD+GY L G CT G W+ P C
Sbjct: 851 CPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHC-KE 909
Query: 62 VAFRKPANQSTTVRG 76
V PA+ +G
Sbjct: 910 VNCSSPADMDGIQKG 924
Score = 38.7 bits (86), Expect = 0.11
Identities = 19/56 (33%), Positives = 25/56 (44%), Gaps = 2/56 (3%)
Query: 5 PAVPP--NARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
PA+P N + N +I G Y C+ GY L G + C G W+ PP C
Sbjct: 155 PALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTC 210
Score = 36.3 bits (80), Expect = 0.60
Identities = 19/54 (35%), Positives = 24/54 (44%), Gaps = 3/54 (5%)
Query: 8 PPNARVSIPNEENIVA---GTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
PPN + ++V GT Y C+ GY L G +CT G WT P C
Sbjct: 413 PPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQC 466
Score = 36.3 bits (80), Expect = 0.60
Identities = 19/61 (31%), Positives = 28/61 (45%), Gaps = 4/61 (6%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTL----RGDWTLEPPF 57
C P V N + + EN + G YECD+G+ L G ++ +C G W+ P
Sbjct: 719 CHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQ 778
Query: 58 C 58
C
Sbjct: 779 C 779
Score = 34.7 bits (76), Expect = 1.8
Identities = 16/58 (27%), Positives = 26/58 (44%), Gaps = 1/58 (1%)
Query: 1 RCGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
+C HP + VS + T+ ++ C G+ L G++Q C +G W P C
Sbjct: 350 QCPHPQILRGRMVSGQKDRYTYNDTV-IFACMFGFTLKGSKQIRCNAQGTWEPSAPVC 406
>AL391597-6|CAH72951.1| 971|Homo sapiens complement component
(3d/Epstein Barr virus) receptor 2 protein.
Length = 971
Score = 226 bits (552), Expect = 4e-58
Identities = 182/642 (28%), Positives = 265/642 (41%), Gaps = 89/642 (13%)
Query: 372 GSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRTTH 431
G + Y C G++L+G+K +C G WS PP+C+ C L +G V
Sbjct: 176 GLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRV- 234
Query: 432 GARALYSCRENFTLVGNPERTC--GDEGIWDGEAPRCLFDWCPDPPAVSNASVTVN---G 486
G A + C E + L G P C +G+ + P C +CP PP + N N
Sbjct: 235 GVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTKMPVCEEIFCPSPPPILNGRHIGNSLAN 294
Query: 487 HKAGSLASYTC----ENG--HILSGSTSVTCTLG----GAWSGVPPSCKY----VNCGTP 532
GS+ +YTC E G IL G +++ CT+ G WSG P C+ V C P
Sbjct: 295 VSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHP 354
Query: 533 TIHKGSFVL-INGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEP 591
I +G V TY F C + L G++++ CN G W P CE P
Sbjct: 355 QILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKECQAPP 414
Query: 592 EVPSG----GYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCG 647
+ +G +M FD ++I + C G+ L+GE ++ C +G W+ P C+ C
Sbjct: 415 NILNGQKEDRHMVRFD--PGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACE 472
Query: 648 KLPTLPYGTMELLNGTTH--LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIR 705
+LL H + + SC Y+L G V + C W C+EI
Sbjct: 473 AT------GRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEIT 526
Query: 706 CSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKG------YKV 759
C P V N G +L + G V Y C G + +
Sbjct: 527 CPPP--------PVIYNGAHTGSSL----------EDFPYGTTVTYTCNPGPERGVEFSL 568
Query: 760 IGESLSTCEDN----GQWSGTTPTCQY----VDCGNPGRIENG-KVTLPSNATFYGATAF 810
IGES C N G WSG P C+ V C + I NG K++ FY T
Sbjct: 569 IGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHV-HIANGYKISGKEAPYFYNDTVT 627
Query: 811 YQCDENWELEGVIRRMCQENGTWSLEPPICKEITCP---DPSAQIKAGSGLLVVTSTLSI 867
++C + L+G + C+ + TW E P+C++ TC ++ AGS + +V ++
Sbjct: 628 FKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKETCQHVRQSLQELPAGSRVELVNTS--- 684
Query: 868 GGEAHYQCERGYNLKGHQTRTC--ISKGQWNGTVPVCIPIDCRSPGNIENGKIV-ISNGS 924
C+ GY L GH + C G W +P+C I C P I NGK + +
Sbjct: 685 -------CQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAEN 737
Query: 925 TLFGSSVEYYCLSQYQRVGPFLRKCLDD----GRWSGEEPSC 962
L+G+ V Y C + +G +C D G WSG P C
Sbjct: 738 FLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQC 779
Score = 215 bits (524), Expect = 9e-55
Identities = 190/672 (28%), Positives = 277/672 (41%), Gaps = 81/672 (12%)
Query: 352 TCGSPDKLLNTTI--LGNDYDVGSRIVYKCPEGHMLLGDKSRHC----KKDGFWSGAPPS 405
+CGSP +LN I VG+ I Y C L+G+KS C K DG W P
Sbjct: 22 SCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPK 81
Query: 406 CKYVN--CGGLTPIEDGDVALIDNRT-THGARALYSCRENFTLVGNPERTCGDEGIWDG- 461
C+Y N PI G + + HG ++C+ NF++ GN C +W
Sbjct: 82 CEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWGPT 141
Query: 462 EAPRCLFDW---CPDPPAVSNA---SVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGG 515
P C+ + CP P + N S V G +Y+CE+G++L G + C G
Sbjct: 142 RLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSG 201
Query: 516 AWSGVPPSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGK 575
WS VPP+C+ C + V G A F C+ Y L G C G+
Sbjct: 202 KWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQ 261
Query: 576 ---WSYDIPSCELTSCPE-PEVPSGGYM--EAFDYYVHSTINFHCEAGHK------LIGE 623
W+ +P CE CP P + +G ++ + S + + C+ + LIGE
Sbjct: 262 GVAWT-KMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGE 320
Query: 624 PNLVC----QQDGEWSGDSPTCEY----IDCGKLPTLPYGTM--ELLNGTTHLGSVIQYS 673
L C Q+ G WSG +P CE + C P + G M + T+ +VI ++
Sbjct: 321 STLRCTVDSQKTGTWSGPAPRCELSTSAVQCPH-PQILRGRMVSGQKDRYTYNDTVI-FA 378
Query: 674 CTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRT 733
C + L G + C + W S+P CE+ C P +I++ DR ++R
Sbjct: 379 CMFGFTLKGSKQIRCNAQGTWEPSAPVCEK-ECQAP----PNILNGQKEDRH----MVR- 428
Query: 734 SDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIEN 793
+ G +KY C GY ++GE C G W+ P C+ C GR
Sbjct: 429 ---------FDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGR--- 476
Query: 794 GKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIK 853
+T P + F C E ++L G + + CQ W +E +CKEITCP P I
Sbjct: 477 QLLTKPQH-QFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPV-IY 534
Query: 854 AGSGLLVVTSTLSIGGEAHYQC----ERG--YNLKGHQTRTCIS----KGQWNGTVPVC- 902
G+ G Y C ERG ++L G T C S +G W+G P+C
Sbjct: 535 NGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCK 594
Query: 903 ---IPIDCRSPGNIENG-KIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGE 958
+ + C S +I NG KI + +V + C S + G +C D W E
Sbjct: 595 LSLLAVQC-SHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPE 653
Query: 959 EPSCELATNEAV 970
P CE T + V
Sbjct: 654 IPVCEKETCQHV 665
Score = 189 bits (461), Expect = 4e-47
Identities = 168/661 (25%), Positives = 266/661 (40%), Gaps = 93/661 (14%)
Query: 353 CGSPDKLLNTTILGN---DYDVGSRIVYKC---PE---GHMLLGDKSRHC----KKDGFW 399
C SP +LN +GN + GS + Y C PE +L+G+ + C +K G W
Sbjct: 276 CPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTW 335
Query: 400 SGAPPSCKY----VNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGD 455
SG P C+ V C + V+ +R T+ +++C FTL G+ + C
Sbjct: 336 SGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNA 395
Query: 456 EGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKA----GSLASYTCENGHILSGSTSVTC 511
+G W+ AP C + C PP + N + H G+ Y+C G++L G S+ C
Sbjct: 396 QGTWEPSAPVCEKE-CQAPPNILNGQKE-DRHMVRFDPGTSIKYSCNPGYVLVGEESIQC 453
Query: 512 TLGGAWSGVPPSCKYVNC---GTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEEL 568
T G W+ P CK C G + K + +C Y L+G+
Sbjct: 454 TSEGVWTPPVPQCKVAACEATGRQLLTKPQHQFVRPDVNS------SCGEGYKLSGSVYQ 507
Query: 569 VCNRDGKWSYDIPSCELTSCPEPEV-----PSGGYMEAFDYYVHSTINFHCEAGHK---- 619
C W +I C+ +CP P V +G +E F Y +T+ + C G +
Sbjct: 508 ECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPY--GTTVTYTCNPGPERGVE 565
Query: 620 --LIGEPNLVC----QQDGEWSGDSPTCEY----IDCGKLPTLPYGTMELLNGTTHLGSV 669
LIGE + C Q+ G WSG +P C+ + C + +
Sbjct: 566 FSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDT 625
Query: 670 IQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHT 729
+ + C + + L G + C + W P CE+ C +S+ + R
Sbjct: 626 VTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKETCQH---VRQSLQELPAGSRVE--- 679
Query: 730 LIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCED--NGQWSGTTPTCQYVDCGN 787
L+ TS C+ GY++ G + C+D NG W P C+ + C
Sbjct: 680 LVNTS------------------CQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHP 721
Query: 788 PGRIENGKVT-LPSNATFYGATAFYQCDENWELEGVIRRMCQEN----GTWSLEPPICKE 842
P I NGK T + + YG Y+CD+ + L G + C+ + G+WS P C
Sbjct: 722 PPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLR 781
Query: 843 ---IT-CPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGT 898
+T CP+P ++K G L S S + C G+ + G + C + W
Sbjct: 782 SPPVTRCPNP--EVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPG 839
Query: 899 VPVCI--PIDCRSPGNIEN-GKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRW 955
VP CI ++C SP +++ K + +G+ V C Y G +C D +W
Sbjct: 840 VPTCIKKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSDHQW 899
Query: 956 S 956
+
Sbjct: 900 N 900
Score = 178 bits (433), Expect = 1e-43
Identities = 159/612 (25%), Positives = 239/612 (39%), Gaps = 81/612 (13%)
Query: 404 PSCKYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTC----GDEGIW 459
P ++CG PI +G ++ G YSC F L+G C +G W
Sbjct: 16 PGVLGISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTW 75
Query: 460 DGEAPRC----LFDWCPDPPAVSNASVT-VNGHKAGSLASYTCENGHILSGSTSVTCTLG 514
D AP+C + CP+P + ++ G ++ C+ ++G+ SV C
Sbjct: 76 DKPAPKCEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQAN 135
Query: 515 GAWSGVP-PSCKYV---NC-GTPTIHKGSFVLIN-GTTTYGSIAQFTCEPDYWLNGAEEL 568
W P+C V C P IH G N G+ G ++CE Y L G + +
Sbjct: 136 NMWGPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKII 195
Query: 569 VCNRDGKWSYDIPSCELTSCPE-PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLV 627
C GKWS P+CE C P+G E V T NF C+ G++L G P+
Sbjct: 196 NCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSR 255
Query: 628 CQQDGE---WSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHL--GSVIQYSCT------T 676
C G+ W+ P CE I C P + G + N ++ GS++ Y+C
Sbjct: 256 CVIAGQGVAWT-KMPVCEEIFCPSPPPILNG-RHIGNSLANVSYGSIVTYTCDPDPEEGV 313
Query: 677 NYRLVGPVRRTCTEEFQ----WSDSSPRCE----EIRCSDPIVAEKSIVSVTGNDRSHGH 728
N+ L+G CT + Q WS +PRCE ++C P + +VS + ++
Sbjct: 314 NFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYTYND 373
Query: 729 TLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNP 788
T+I + C G+ + G C G W + P C+ +C P
Sbjct: 374 TVI-------------------FACMFGFTLKGSKQIRCNAQGTWEPSAPVCE-KECQAP 413
Query: 789 GRIENGKVTLPSNATFYGATAF-YQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPD 847
I NG+ F T+ Y C+ + L G C G W+ P CK C
Sbjct: 414 PNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACE- 472
Query: 848 PSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDC 907
G LL + + + C GY L G + C W + +C I C
Sbjct: 473 -----ATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITC 527
Query: 908 RSPGNIENGKIVISNGSTL----FGSSVEYYCLS------QYQRVGPFLRKCLDD----G 953
P I NG GS+L +G++V Y C ++ +G +C + G
Sbjct: 528 PPPPVIYNG---AHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERG 584
Query: 954 RWSGEEPSCELA 965
WSG P C+L+
Sbjct: 585 TWSGPAPLCKLS 596
Score = 165 bits (400), Expect = 1e-39
Identities = 137/536 (25%), Positives = 218/536 (40%), Gaps = 68/536 (12%)
Query: 369 YDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNR 428
+D G+ I Y C G++L+G++S C +G W+ P CK C E L+
Sbjct: 429 FDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAAC------EATGRQLLTKP 482
Query: 429 TTHGAR--ALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVT--- 483
R SC E + L G+ + C W E C CP PP + N + T
Sbjct: 483 QHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSS 542
Query: 484 VNGHKAGSLASYTCENG------HILSGSTSVTCTLG----GAWSGVPPSCKY----VNC 529
+ G+ +YTC G L G +++ CT G WSG P CK V C
Sbjct: 543 LEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQC 602
Query: 530 GTPTIHKGSFVLINGTTT---YGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELT 586
+H + I+G Y F C + L G+ ++ C D W +IP CE
Sbjct: 603 SH--VHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKE 660
Query: 587 SCPE-----PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQ--QDGEWSGDSP 639
+C E+P+G +E +N C+ G++L G +CQ ++G W P
Sbjct: 661 TCQHVRQSLQELPAGSRVEL--------VNTSCQDGYQLTGHAYQMCQDAENGIWFKKIP 712
Query: 640 TCEYIDCGKLPTLPYGTMELLNGTTHL-GSVIQYSCTTNYRLVGPVRRTCTEEFQ----W 694
C+ I C P + G + L G+ + Y C + L+G + C + + W
Sbjct: 713 LCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSW 772
Query: 695 SDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCE 754
S SP+C +R S P+ + HG+ L +T + Y +V C
Sbjct: 773 SGPSPQC--LR-SPPVTR------CPNPEVKHGYKLNKTH------SAYSHNDIVYVDCN 817
Query: 755 KGYKVIGESLSTCEDNGQWSGTTPTC--QYVDCGNPGRIENGKVTL-PSNATFYGATAFY 811
G+ + G + C + W PTC + V+C +P ++ + L P YGA
Sbjct: 818 PGFIMNGSRVIRCHTDNTWVPGVPTCIKKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTL 877
Query: 812 QCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSI 867
+C++ + LEG + CQ + W+ +C+ + I AG LL +++
Sbjct: 878 ECEDGYMLEGSPQSQCQSDHQWNPPLAVCRSRSLAPVLCGIAAGLILLTFLIVITL 933
Score = 164 bits (398), Expect = 2e-39
Identities = 150/586 (25%), Positives = 220/586 (37%), Gaps = 66/586 (11%)
Query: 353 CGSPDKLLNTTILGND--YDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVN 410
C P L + G Y +++ C G L G K C G W + P C+
Sbjct: 351 CPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEK-E 409
Query: 411 CGGLTPIEDG---DVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL 467
C I +G D ++ R G YSC + LVG C EG+W P+C
Sbjct: 410 CQAPPNILNGQKEDRHMV--RFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCK 467
Query: 468 FDWCPDPPAVSNASVTVNGHK-AGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKY 526
C A +T H+ + +C G+ LSGS C W CK
Sbjct: 468 VAACE---ATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKE 524
Query: 527 VNCGTP-TIHKGSFVLIN-GTTTYGSIAQFTCEP------DYWLNGAEELVCNRD----G 574
+ C P I+ G+ + YG+ +TC P ++ L G + C + G
Sbjct: 525 ITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERG 584
Query: 575 KWSYDIPSCELT----SCPEPEVPSGGYMEAFD--YYVHSTINFHCEAGHKLIGEPNLVC 628
WS P C+L+ C + +G + + Y+ + T+ F C +G L G + C
Sbjct: 585 TWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRC 644
Query: 629 QQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTC 688
+ D W + P CE C + EL G+ ++ SC Y+L G + C
Sbjct: 645 KADNTWDPEIPVCEKETCQHVRQ---SLQELPAGSRV--ELVNTSCQDGYQLTGHAYQMC 699
Query: 689 --TEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIG 746
E W P C+ I C P V V G HT + ++N GN
Sbjct: 700 QDAENGIWFKKIPLCKVIHCHPPPVI------VNGK-----HTGMM-AENFLYGNE---- 743
Query: 747 ALVKYRCEKGYKVIGESLSTCEDN----GQWSGTTPTC----QYVDCGNPGRIENGKVTL 798
V Y C++G+ ++GE C + G WSG +P C C NP K+
Sbjct: 744 --VSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNK 801
Query: 799 PSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPIC--KEITCPDPSAQIKAGS 856
+A + + C+ + + G C + TW P C KE+ C P+
Sbjct: 802 THSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPTCIKKEVNCSSPADMDGIQK 861
Query: 857 GLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVC 902
GL G +CE GY L+G C S QWN + VC
Sbjct: 862 GL-EPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSDHQWNPPLAVC 906
Score = 38.7 bits (86), Expect = 0.11
Identities = 19/56 (33%), Positives = 25/56 (44%), Gaps = 2/56 (3%)
Query: 5 PAVPP--NARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
PA+P N + N +I G Y C+ GY L G + C G W+ PP C
Sbjct: 155 PALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTC 210
Score = 36.3 bits (80), Expect = 0.60
Identities = 19/54 (35%), Positives = 24/54 (44%), Gaps = 3/54 (5%)
Query: 8 PPNARVSIPNEENIVA---GTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
PPN + ++V GT Y C+ GY L G +CT G WT P C
Sbjct: 413 PPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQC 466
Score = 36.3 bits (80), Expect = 0.60
Identities = 19/61 (31%), Positives = 28/61 (45%), Gaps = 4/61 (6%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTL----RGDWTLEPPF 57
C P V N + + EN + G YECD+G+ L G ++ +C G W+ P
Sbjct: 719 CHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQ 778
Query: 58 C 58
C
Sbjct: 779 C 779
Score = 34.7 bits (76), Expect = 1.8
Identities = 16/58 (27%), Positives = 26/58 (44%), Gaps = 1/58 (1%)
Query: 1 RCGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
+C HP + VS + T+ ++ C G+ L G++Q C +G W P C
Sbjct: 350 QCPHPQILRGRMVSGQKDRYTYNDTV-IFACMFGFTLKGSKQIRCNAQGTWEPSAPVC 406
>BC090937-1|AAH90937.1| 1033|Homo sapiens complement component
(3d/Epstein Barr virus) receptor 2 protein.
Length = 1033
Score = 225 bits (551), Expect = 5e-58
Identities = 182/642 (28%), Positives = 265/642 (41%), Gaps = 89/642 (13%)
Query: 372 GSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRTTH 431
G + Y C G++L+G+K +C G WS PP+C+ C L +G V
Sbjct: 176 GLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRV- 234
Query: 432 GARALYSCRENFTLVGNPERTC--GDEGIWDGEAPRCLFDWCPDPPAVSNASVTVN---G 486
G A + C E + L G P C +G+ + P C +CP PP + N N
Sbjct: 235 GVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTKMPVCEEIFCPSPPPILNGRHIGNSLAN 294
Query: 487 HKAGSLASYTC----ENG--HILSGSTSVTCTLG----GAWSGVPPSCKY----VNCGTP 532
GS+ +YTC E G IL G +++ CT+ G WSG P C+ V C P
Sbjct: 295 VSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHP 354
Query: 533 TIHKGSFVL-INGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEP 591
I +G V TY F C + L G++++ CN G W P CE P
Sbjct: 355 QILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKECQAPP 414
Query: 592 EVPSG----GYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCG 647
+ +G +M FD ++I + C G+ L+GE ++ C +G W+ P C+ C
Sbjct: 415 NILNGQKEDRHMVRFD--PGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACE 472
Query: 648 KLPTLPYGTMELLNGTTH--LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIR 705
+LL H + + SC Y+L G V + C W C+EI
Sbjct: 473 AT------GRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEIT 526
Query: 706 CSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKG------YKV 759
C P V N G +L + G V Y C G + +
Sbjct: 527 CPPP--------PVIYNGAHTGSSL----------EDFPYGTTVTYTCNPGPERGVEFSL 568
Query: 760 IGESLSTCEDN----GQWSGTTPTCQY----VDCGNPGRIENG-KVTLPSNATFYGATAF 810
IGES C N G WSG P C+ V C + I NG K++ FY T
Sbjct: 569 IGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHV-HIANGYKISGKEAPYFYNDTVT 627
Query: 811 YQCDENWELEGVIRRMCQENGTWSLEPPICKEITCP---DPSAQIKAGSGLLVVTSTLSI 867
++C + L+G + C+ + TW E P+C++ TC ++ AGS + +V ++
Sbjct: 628 FKCYSGFTLKGNSQIRCKADNTWDPEIPVCEKETCQHVRQSLQELPAGSRVELVNTS--- 684
Query: 868 GGEAHYQCERGYNLKGHQTRTC--ISKGQWNGTVPVCIPIDCRSPGNIENGKIV-ISNGS 924
C+ GY L GH + C G W +P+C I C P I NGK + +
Sbjct: 685 -------CQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAEN 737
Query: 925 TLFGSSVEYYCLSQYQRVGPFLRKCLDD----GRWSGEEPSC 962
L+G+ V Y C + +G +C D G WSG P C
Sbjct: 738 FLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQC 779
Score = 214 bits (523), Expect = 1e-54
Identities = 190/672 (28%), Positives = 277/672 (41%), Gaps = 81/672 (12%)
Query: 352 TCGSPDKLLNTTI--LGNDYDVGSRIVYKCPEGHMLLGDKSRHC----KKDGFWSGAPPS 405
+CGSP +LN I VG+ I Y C L+G+KS C K DG W P
Sbjct: 22 SCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPK 81
Query: 406 CKYVN--CGGLTPIEDGDVALIDNRT-THGARALYSCRENFTLVGNPERTCGDEGIWDG- 461
C+Y N PI G + + HG ++C+ NF++ GN C +W
Sbjct: 82 CEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWGPT 141
Query: 462 EAPRCLFDW---CPDPPAVSNA---SVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGG 515
P C+ + CP P + N S V G +Y+CE+G++L G + C G
Sbjct: 142 RLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSG 201
Query: 516 AWSGVPPSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGK 575
WS VPP+C+ C + V G A F C+ Y L G C G+
Sbjct: 202 KWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQ 261
Query: 576 ---WSYDIPSCELTSCPE-PEVPSGGYM--EAFDYYVHSTINFHCEAGHK------LIGE 623
W+ +P CE CP P + +G ++ + S + + C+ + LIGE
Sbjct: 262 GVAWT-KMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGE 320
Query: 624 PNLVC----QQDGEWSGDSPTCEY----IDCGKLPTLPYGTM--ELLNGTTHLGSVIQYS 673
L C Q+ G WSG +P CE + C P + G M + T+ +VI ++
Sbjct: 321 STLRCTVDSQKTGTWSGPAPRCELSTSAVQCPH-PQILRGRMVSGQKDRYTYNDTVI-FA 378
Query: 674 CTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRT 733
C + L G + C + W S+P CE+ C P +I++ DR ++R
Sbjct: 379 CMFGFTLKGSKQIRCNAQGTWEPSAPVCEK-ECQAP----PNILNGQKEDRH----MVR- 428
Query: 734 SDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIEN 793
+ G +KY C GY ++GE C G W+ P C+ C GR
Sbjct: 429 ---------FDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGR--- 476
Query: 794 GKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIK 853
+T P + F C E ++L G + + CQ W +E +CKEITCP P I
Sbjct: 477 QLLTKPQH-QFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPV-IY 534
Query: 854 AGSGLLVVTSTLSIGGEAHYQC----ERG--YNLKGHQTRTCIS----KGQWNGTVPVC- 902
G+ G Y C ERG ++L G T C S +G W+G P+C
Sbjct: 535 NGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCK 594
Query: 903 ---IPIDCRSPGNIENG-KIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGE 958
+ + C S +I NG KI + +V + C S + G +C D W E
Sbjct: 595 LSLLAVQC-SHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGNSQIRCKADNTWDPE 653
Query: 959 EPSCELATNEAV 970
P CE T + V
Sbjct: 654 IPVCEKETCQHV 665
Score = 200 bits (489), Expect = 2e-50
Identities = 176/669 (26%), Positives = 267/669 (39%), Gaps = 94/669 (14%)
Query: 353 CGSPDKLLNTTILGN---DYDVGSRIVYKC---PE---GHMLLGDKSRHC----KKDGFW 399
C SP +LN +GN + GS + Y C PE +L+G+ + C +K G W
Sbjct: 276 CPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTW 335
Query: 400 SGAPPSCKY----VNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGD 455
SG P C+ V C + V+ +R T+ +++C FTL G+ + C
Sbjct: 336 SGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNA 395
Query: 456 EGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKA----GSLASYTCENGHILSGSTSVTC 511
+G W+ AP C + C PP + N + H G+ Y+C G++L G S+ C
Sbjct: 396 QGTWEPSAPVCEKE-CQAPPNILNGQKE-DRHMVRFDPGTSIKYSCNPGYVLVGEESIQC 453
Query: 512 TLGGAWSGVPPSCKYVNC---GTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEEL 568
T G W+ P CK C G + K + +C Y L+G+
Sbjct: 454 TSEGVWTPPVPQCKVAACEATGRQLLTKPQHQFVRPDVNS------SCGEGYKLSGSVYQ 507
Query: 569 VCNRDGKWSYDIPSCELTSCPEPEV-----PSGGYMEAFDYYVHSTINFHCEAGHK---- 619
C W +I C+ +CP P V +G +E F Y +T+ + C G +
Sbjct: 508 ECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPY--GTTVTYTCNPGPERGVE 565
Query: 620 --LIGEPNLVC----QQDGEWSGDSPTCEY----IDCGKLPTLPYGTMELLNGTTHLGSV 669
LIGE + C Q+ G WSG +P C+ + C + +
Sbjct: 566 FSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDT 625
Query: 670 IQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHT 729
+ + C + + L G + C + W P CE+ C +S+ + R
Sbjct: 626 VTFKCYSGFTLKGNSQIRCKADNTWDPEIPVCEKETCQH---VRQSLQELPAGSRVE--- 679
Query: 730 LIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCED--NGQWSGTTPTCQYVDCGN 787
L+ TS C+ GY++ G + C+D NG W P C+ + C
Sbjct: 680 LVNTS------------------CQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHP 721
Query: 788 PGRIENGKVT-LPSNATFYGATAFYQCDENWELEGVIRRMCQEN----GTWSLEPPICKE 842
P I NGK T + + YG Y+CD+ + L G + C+ + G+WS P C
Sbjct: 722 PPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLR 781
Query: 843 ---IT-CPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGT 898
+T CP+P ++K G L S S + C G+ + G + C + W
Sbjct: 782 SPPVTRCPNP--EVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPG 839
Query: 899 VPVCIP---IDCRSPGNIENGKIVISNGSTLF-GSSVEYYCLSQYQRVGPFLRKCLDDGR 954
VP CI I C P NG N + G S+ Y C Y VG L C +G
Sbjct: 840 VPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGT 899
Query: 955 WSGEEPSCE 963
WS P C+
Sbjct: 900 WSQPAPHCK 908
Score = 198 bits (484), Expect = 7e-50
Identities = 156/572 (27%), Positives = 230/572 (40%), Gaps = 70/572 (12%)
Query: 369 YDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNR 428
+D G+ I Y C G++L+G++S C +G W+ P CK C E L+
Sbjct: 429 FDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAAC------EATGRQLLTKP 482
Query: 429 TTHGAR--ALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVT--- 483
R SC E + L G+ + C W E C CP PP + N + T
Sbjct: 483 QHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSS 542
Query: 484 VNGHKAGSLASYTCENG------HILSGSTSVTCTLG----GAWSGVPPSCKY----VNC 529
+ G+ +YTC G L G +++ CT G WSG P CK V C
Sbjct: 543 LEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQC 602
Query: 530 GTPTIHKGSFVLINGTTT---YGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELT 586
+H + I+G Y F C + L G ++ C D W +IP CE
Sbjct: 603 SH--VHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGNSQIRCKADNTWDPEIPVCEKE 660
Query: 587 SCPE-----PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQ--QDGEWSGDSP 639
+C E+P+G +E +N C+ G++L G +CQ ++G W P
Sbjct: 661 TCQHVRQSLQELPAGSRVEL--------VNTSCQDGYQLTGHAYQMCQDAENGIWFKKIP 712
Query: 640 TCEYIDCGKLPTLPYGTMELLNGTTHL-GSVIQYSCTTNYRLVGPVRRTCTEEFQ----W 694
C+ I C P + G + L G+ + Y C + L+G + C + + W
Sbjct: 713 LCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSW 772
Query: 695 SDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCE 754
S SP+C +R S P+ + HG+ L +T + Y +V C
Sbjct: 773 SGPSPQC--LR-SPPVTR------CPNPEVKHGYKLNKTH------SAYSHNDIVYVDCN 817
Query: 755 KGYKVIGESLSTCEDNGQWSGTTPTC---QYVDCGNPGRIENGKVTLPSNATFY-GATAF 810
G+ + G + C + W PTC ++ C P + NG T + A F G +
Sbjct: 818 PGFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSIL 877
Query: 811 YQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGE 870
Y CD+ + L G +C GTWS P CKE+ C P+ GL G
Sbjct: 878 YSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVNCSSPADMDGIQKGL-EPRKMYQYGAV 936
Query: 871 AHYQCERGYNLKGHQTRTCISKGQWNGTVPVC 902
+CE GY L+G C S QWN + VC
Sbjct: 937 VTLECEDGYMLEGSPQSQCQSDHQWNPPLAVC 968
Score = 178 bits (433), Expect = 1e-43
Identities = 159/612 (25%), Positives = 239/612 (39%), Gaps = 81/612 (13%)
Query: 404 PSCKYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTC----GDEGIW 459
P ++CG PI +G ++ G YSC F L+G C +G W
Sbjct: 16 PGVLGISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTW 75
Query: 460 DGEAPRC----LFDWCPDPPAVSNASVT-VNGHKAGSLASYTCENGHILSGSTSVTCTLG 514
D AP+C + CP+P + ++ G ++ C+ ++G+ SV C
Sbjct: 76 DKPAPKCEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQAN 135
Query: 515 GAWSGVP-PSCKYV---NC-GTPTIHKGSFVLIN-GTTTYGSIAQFTCEPDYWLNGAEEL 568
W P+C V C P IH G N G+ G ++CE Y L G + +
Sbjct: 136 NMWGPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKII 195
Query: 569 VCNRDGKWSYDIPSCELTSCPE-PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLV 627
C GKWS P+CE C P+G E V T NF C+ G++L G P+
Sbjct: 196 NCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSR 255
Query: 628 CQQDGE---WSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHL--GSVIQYSCT------T 676
C G+ W+ P CE I C P + G + N ++ GS++ Y+C
Sbjct: 256 CVIAGQGVAWT-KMPVCEEIFCPSPPPILNG-RHIGNSLANVSYGSIVTYTCDPDPEEGV 313
Query: 677 NYRLVGPVRRTCTEEFQ----WSDSSPRCE----EIRCSDPIVAEKSIVSVTGNDRSHGH 728
N+ L+G CT + Q WS +PRCE ++C P + +VS + ++
Sbjct: 314 NFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYTYND 373
Query: 729 TLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNP 788
T+I + C G+ + G C G W + P C+ +C P
Sbjct: 374 TVI-------------------FACMFGFTLKGSKQIRCNAQGTWEPSAPVCE-KECQAP 413
Query: 789 GRIENGKVTLPSNATFYGATAF-YQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPD 847
I NG+ F T+ Y C+ + L G C G W+ P CK C
Sbjct: 414 PNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACE- 472
Query: 848 PSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDC 907
G LL + + + C GY L G + C W + +C I C
Sbjct: 473 -----ATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITC 527
Query: 908 RSPGNIENGKIVISNGSTL----FGSSVEYYCLS------QYQRVGPFLRKCLDD----G 953
P I NG GS+L +G++V Y C ++ +G +C + G
Sbjct: 528 PPPPVIYNG---AHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERG 584
Query: 954 RWSGEEPSCELA 965
WSG P C+L+
Sbjct: 585 TWSGPAPLCKLS 596
Score = 173 bits (421), Expect = 3e-42
Identities = 160/642 (24%), Positives = 244/642 (38%), Gaps = 68/642 (10%)
Query: 353 CGSPDKLLNTTILGND--YDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVN 410
C P L + G Y +++ C G L G K C G W + P C+
Sbjct: 351 CPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEK-E 409
Query: 411 CGGLTPIEDG---DVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL 467
C I +G D ++ R G YSC + LVG C EG+W P+C
Sbjct: 410 CQAPPNILNGQKEDRHMV--RFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCK 467
Query: 468 FDWCPDPPAVSNASVTVNGHK-AGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKY 526
C A +T H+ + +C G+ LSGS C W CK
Sbjct: 468 VAACE---ATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKE 524
Query: 527 VNCGTP-TIHKGSFVLIN-GTTTYGSIAQFTCEP------DYWLNGAEELVCNRD----G 574
+ C P I+ G+ + YG+ +TC P ++ L G + C + G
Sbjct: 525 ITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERG 584
Query: 575 KWSYDIPSCELT----SCPEPEVPSGGYMEAFD--YYVHSTINFHCEAGHKLIGEPNLVC 628
WS P C+L+ C + +G + + Y+ + T+ F C +G L G + C
Sbjct: 585 TWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGNSQIRC 644
Query: 629 QQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTC 688
+ D W + P CE C + EL G+ ++ SC Y+L G + C
Sbjct: 645 KADNTWDPEIPVCEKETCQHVRQ---SLQELPAGSRV--ELVNTSCQDGYQLTGHAYQMC 699
Query: 689 --TEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIG 746
E W P C+ I C P V V G HT + ++N GN
Sbjct: 700 QDAENGIWFKKIPLCKVIHCHPPPVI------VNGK-----HTGMM-AENFLYGNE---- 743
Query: 747 ALVKYRCEKGYKVIGESLSTCEDN----GQWSGTTPTC----QYVDCGNPGRIENGKVTL 798
V Y C++G+ ++GE C + G WSG +P C C NP K+
Sbjct: 744 --VSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNK 801
Query: 799 PSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKE---ITCPDPSAQIKAG 855
+A + + C+ + + G C + TW P C + I CP P + G
Sbjct: 802 THSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPP-KTPNG 860
Query: 856 SGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIEN 915
+ + S G Y C++GY L G C +G W+ P C ++C SP +++
Sbjct: 861 NHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVNCSSPADMDG 920
Query: 916 -GKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWS 956
K + +G+ V C Y G +C D +W+
Sbjct: 921 IQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSDHQWN 962
Score = 154 bits (374), Expect = 1e-36
Identities = 124/465 (26%), Positives = 182/465 (39%), Gaps = 56/465 (12%)
Query: 352 TCGSPDKLLNTTILGN---DYDVGSRIVYKCPEG------HMLLGDKSRHCKKD----GF 398
TC P + N G+ D+ G+ + Y C G L+G+ + C + G
Sbjct: 526 TCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGT 585
Query: 399 WSGAPPSCKY----VNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCG 454
WSG P CK V C + ++ + + + C FTL GN + C
Sbjct: 586 WSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGNSQIRCK 645
Query: 455 DEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTC--T 512
+ WD E P C + C V + + L + +C++G+ L+G C
Sbjct: 646 ADNTWDPEIPVCEKETCQH---VRQSLQELPAGSRVELVNTSCQDGYQLTGHAYQMCQDA 702
Query: 513 LGGAWSGVPPSCKYVNCGTP-TIHKGSFV-LINGTTTYGSIAQFTCEPDYWLNGAEELVC 570
G W P CK ++C P I G ++ YG+ + C+ ++L G ++L C
Sbjct: 703 ENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQC 762
Query: 571 NRD----GKWSYDIPSC----ELTSCPEPEVPSGGYM-EAFDYYVHSTINF-HCEAGHKL 620
D G WS P C +T CP PEV G + + Y H+ I + C G +
Sbjct: 763 RSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIM 822
Query: 621 IGEPNLVCQQDGEWSGDSPTC---EYIDCGKLPTLPYGTMELLN-GTTHLGSVIQYSCTT 676
G + C D W PTC +I C P P G N G I YSC
Sbjct: 823 NGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQ 882
Query: 677 NYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDN 736
Y LVG CT E WS +P C+E+ CS P + G +
Sbjct: 883 GYLLVGEALLLCTHEGTWSQPAPHCKEVNCSSP-------ADMDGIQK-----------G 924
Query: 737 RDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQ 781
+ Y+ GA+V CE GY + G S C+ + QW+ C+
Sbjct: 925 LEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSDHQWNPPLAVCR 969
Score = 136 bits (329), Expect = 4e-31
Identities = 128/528 (24%), Positives = 205/528 (38%), Gaps = 66/528 (12%)
Query: 379 CPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDG-DVALIDNRTTHGARALY 437
C EG+ L G + C+ W CK + C I +G +G Y
Sbjct: 495 CGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTY 554
Query: 438 SCREN------FTLVGNPERTCG----DEGIWDGEAPRCLFDWCPDPPAVSNASVTV-NG 486
+C F+L+G C + G W G AP C AV + V + NG
Sbjct: 555 TCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLL----AVQCSHVHIANG 610
Query: 487 HK-AGSLASY--------TCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTIHKG 537
+K +G A Y C +G L G++ + C W P C+ C + +
Sbjct: 611 YKISGKEAPYFYNDTVTFKCYSGFTLKGNSQIRCKADNTWDPEIPVCEKETC--QHVRQS 668
Query: 538 SFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCN--RDGKWSYDIPSCELTSC-PEPEVP 594
L G+ + +C+ Y L G +C +G W IP C++ C P P +
Sbjct: 669 LQELPAGSRV--ELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIV 726
Query: 595 SGGY--MEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQD----GEWSGDSPTC----EYI 644
+G + M A ++ + +++ C+ G L+GE L C+ D G WSG SP C
Sbjct: 727 NGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVT 786
Query: 645 DCGKLPTLPYG-TMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEE 703
C P + +G + + ++ C + + G C + W P C +
Sbjct: 787 RCPN-PEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPTCIK 845
Query: 704 ---IRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVI 760
I C P T N G + R S G + Y C++GY ++
Sbjct: 846 KAFIGCPPP--------PKTPNGNHTGGNIARFSP----------GMSILYSCDQGYLLV 887
Query: 761 GESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTL-PSNATFYGATAFYQCDENWEL 819
GE+L C G WS P C+ V+C +P ++ + L P YGA +C++ + L
Sbjct: 888 GEALLLCTHEGTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYML 947
Query: 820 EGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSI 867
EG + CQ + W+ +C+ + I AG LL +++
Sbjct: 948 EGSPQSQCQSDHQWNPPLAVCRSRSLAPVLCGIAAGLILLTFLIVITL 995
Score = 108 bits (259), Expect = 1e-22
Identities = 71/256 (27%), Positives = 106/256 (41%), Gaps = 23/256 (8%)
Query: 353 CGSPDKLLN---TTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKD----GFWSGAPPS 405
C P ++N T ++ ++ G+ + Y+C +G LLG+K C+ D G WSG P
Sbjct: 719 CHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQ 778
Query: 406 CKYVNCGGLTPIEDGDVALIDNRT----THGARALYSCRENFTLVGNPERTCGDEGIWDG 461
C P + N+T +H C F + G+ C + W
Sbjct: 779 CLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVP 838
Query: 462 EAPRCL---FDWCPDPPAVSNASVT---VNGHKAGSLASYTCENGHILSGSTSVTCTLGG 515
P C+ F CP PP N + T + G Y+C+ G++L G + CT G
Sbjct: 839 GVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEG 898
Query: 516 AWSGVPPSCKYVNCGTPT----IHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCN 571
WS P CK VNC +P I KG + YG++ CE Y L G+ + C
Sbjct: 899 TWSQPAPHCKEVNCSSPADMDGIQKG--LEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQ 956
Query: 572 RDGKWSYDIPSCELTS 587
D +W+ + C S
Sbjct: 957 SDHQWNPPLAVCRSRS 972
Score = 40.3 bits (90), Expect = 0.037
Identities = 23/75 (30%), Positives = 29/75 (38%), Gaps = 1/75 (1%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTN 61
C P PN + N G +Y CD+GY L G CT G W+ P C
Sbjct: 851 CPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHC-KE 909
Query: 62 VAFRKPANQSTTVRG 76
V PA+ +G
Sbjct: 910 VNCSSPADMDGIQKG 924
Score = 38.7 bits (86), Expect = 0.11
Identities = 19/56 (33%), Positives = 25/56 (44%), Gaps = 2/56 (3%)
Query: 5 PAVPP--NARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
PA+P N + N +I G Y C+ GY L G + C G W+ PP C
Sbjct: 155 PALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTC 210
Score = 36.3 bits (80), Expect = 0.60
Identities = 19/54 (35%), Positives = 24/54 (44%), Gaps = 3/54 (5%)
Query: 8 PPNARVSIPNEENIVA---GTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
PPN + ++V GT Y C+ GY L G +CT G WT P C
Sbjct: 413 PPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQC 466
Score = 36.3 bits (80), Expect = 0.60
Identities = 19/61 (31%), Positives = 28/61 (45%), Gaps = 4/61 (6%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTL----RGDWTLEPPF 57
C P V N + + EN + G YECD+G+ L G ++ +C G W+ P
Sbjct: 719 CHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQ 778
Query: 58 C 58
C
Sbjct: 779 C 779
Score = 34.7 bits (76), Expect = 1.8
Identities = 16/58 (27%), Positives = 26/58 (44%), Gaps = 1/58 (1%)
Query: 1 RCGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
+C HP + VS + T+ ++ C G+ L G++Q C +G W P C
Sbjct: 350 QCPHPQILRGRMVSGQKDRYTYNDTV-IFACMFGFTLKGSKQIRCNAQGTWEPSAPVC 406
>Y00649-1|CAA68674.1| 1032|Homo sapiens CR2 receptor protein.
Length = 1032
Score = 219 bits (535), Expect = 4e-56
Identities = 181/642 (28%), Positives = 264/642 (41%), Gaps = 90/642 (14%)
Query: 372 GSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRTTH 431
G + Y C G++L+G+K +C G WS PP+C+ C L +G V
Sbjct: 176 GLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRV- 234
Query: 432 GARALYSCRENFTLVGNPERTC--GDEGIWDGEAPRCLFDWCPDPPAVSNASVTVN---G 486
G A + C E + L G P C +G+ + P C +CP PP + N N
Sbjct: 235 GVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTKMPVCEEIFCPSPPPILNGRHIGNSLAN 294
Query: 487 HKAGSLASYTC----ENG--HILSGSTSVTCTLG----GAWSGVPPSCKY----VNCGTP 532
GS+ +YTC E G IL G +++ CT+ G WSG P C+ V C P
Sbjct: 295 VSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHP 354
Query: 533 TIHKGSFVL-INGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEP 591
I +G V TY F C + L G++++ CN G W P CE P
Sbjct: 355 QILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKECQAPP 414
Query: 592 EVPSG----GYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCG 647
+ +G +M FD ++I + C G+ L+GE ++ C + W+ P C+ C
Sbjct: 415 NILNGQKEDRHMVRFD--PGTSIKYSCNPGYVLVGEESIQCTSE-VWTPPVPQCKVAACE 471
Query: 648 KLPTLPYGTMELLNGTTH--LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIR 705
+LL H + + SC Y+L G V + C W C+EI
Sbjct: 472 AT------GRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEIT 525
Query: 706 CSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKG------YKV 759
C P V N G +L + G V Y C G + +
Sbjct: 526 CPPP--------PVIYNGAHTGSSL----------EDFPYGTTVTYTCNPGPERGVEFSL 567
Query: 760 IGESLSTCEDN----GQWSGTTPTCQY----VDCGNPGRIENG-KVTLPSNATFYGATAF 810
IGES C N G WSG P C+ V C + I NG K++ FY T
Sbjct: 568 IGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHV-HIANGYKISGKEAPYFYNDTVT 626
Query: 811 YQCDENWELEGVIRRMCQENGTWSLEPPICKEITCP---DPSAQIKAGSGLLVVTSTLSI 867
++C + L+G + C+ + TW E P+C++ TC ++ AGS + +V ++
Sbjct: 627 FKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKETCQHVRQSLQELPAGSRVELVNTS--- 683
Query: 868 GGEAHYQCERGYNLKGHQTRTC--ISKGQWNGTVPVCIPIDCRSPGNIENGKIV-ISNGS 924
C+ GY L GH + C G W +P+C I C P I NGK + +
Sbjct: 684 -------CQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAEN 736
Query: 925 TLFGSSVEYYCLSQYQRVGPFLRKCLDD----GRWSGEEPSC 962
L+G+ V Y C + +G +C D G WSG P C
Sbjct: 737 FLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQC 778
Score = 208 bits (507), Expect = 1e-52
Identities = 189/672 (28%), Positives = 276/672 (41%), Gaps = 82/672 (12%)
Query: 352 TCGSPDKLLNTTI--LGNDYDVGSRIVYKCPEGHMLLGDKSRHC----KKDGFWSGAPPS 405
+CGSP +LN I VG+ I Y C L+G+KS C K DG W P
Sbjct: 22 SCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPK 81
Query: 406 CKYVN--CGGLTPIEDGDVALIDNRT-THGARALYSCRENFTLVGNPERTCGDEGIWDG- 461
C+Y N PI G + + HG ++C+ NF++ GN C +W
Sbjct: 82 CEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWGPT 141
Query: 462 EAPRCLFDW---CPDPPAVSNA---SVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGG 515
P C+ + CP P + N S V G +Y+CE+G++L G + C G
Sbjct: 142 RLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSG 201
Query: 516 AWSGVPPSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGK 575
WS VPP+C+ C + V G A F C+ Y L G C G+
Sbjct: 202 KWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQ 261
Query: 576 ---WSYDIPSCELTSCPE-PEVPSGGYM--EAFDYYVHSTINFHCEAGHK------LIGE 623
W+ +P CE CP P + +G ++ + S + + C+ + LIGE
Sbjct: 262 GVAWT-KMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGE 320
Query: 624 PNLVC----QQDGEWSGDSPTCEY----IDCGKLPTLPYGTM--ELLNGTTHLGSVIQYS 673
L C Q+ G WSG +P CE + C P + G M + T+ +VI ++
Sbjct: 321 STLRCTVDSQKTGTWSGPAPRCELSTSAVQCPH-PQILRGRMVSGQKDRYTYNDTVI-FA 378
Query: 674 CTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRT 733
C + L G + C + W S+P CE+ C P +I++ DR ++R
Sbjct: 379 CMFGFTLKGSKQIRCNAQGTWEPSAPVCEK-ECQAP----PNILNGQKEDRH----MVR- 428
Query: 734 SDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIEN 793
+ G +KY C GY ++GE C W+ P C+ C GR
Sbjct: 429 ---------FDPGTSIKYSCNPGYVLVGEESIQCTSE-VWTPPVPQCKVAACEATGR--- 475
Query: 794 GKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIK 853
+T P + F C E ++L G + + CQ W +E +CKEITCP P I
Sbjct: 476 QLLTKPQH-QFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPV-IY 533
Query: 854 AGSGLLVVTSTLSIGGEAHYQC----ERG--YNLKGHQTRTCIS----KGQWNGTVPVC- 902
G+ G Y C ERG ++L G T C S +G W+G P+C
Sbjct: 534 NGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCK 593
Query: 903 ---IPIDCRSPGNIENG-KIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGE 958
+ + C S +I NG KI + +V + C S + G +C D W E
Sbjct: 594 LSLLAVQC-SHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPE 652
Query: 959 EPSCELATNEAV 970
P CE T + V
Sbjct: 653 IPVCEKETCQHV 664
Score = 195 bits (475), Expect = 8e-49
Identities = 175/669 (26%), Positives = 266/669 (39%), Gaps = 95/669 (14%)
Query: 353 CGSPDKLLNTTILGN---DYDVGSRIVYKC---PE---GHMLLGDKSRHC----KKDGFW 399
C SP +LN +GN + GS + Y C PE +L+G+ + C +K G W
Sbjct: 276 CPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTW 335
Query: 400 SGAPPSCKY----VNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGD 455
SG P C+ V C + V+ +R T+ +++C FTL G+ + C
Sbjct: 336 SGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNA 395
Query: 456 EGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKA----GSLASYTCENGHILSGSTSVTC 511
+G W+ AP C + C PP + N + H G+ Y+C G++L G S+ C
Sbjct: 396 QGTWEPSAPVCEKE-CQAPPNILNGQKE-DRHMVRFDPGTSIKYSCNPGYVLVGEESIQC 453
Query: 512 TLGGAWSGVPPSCKYVNC---GTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEEL 568
T W+ P CK C G + K + +C Y L+G+
Sbjct: 454 T-SEVWTPPVPQCKVAACEATGRQLLTKPQHQFVRPDVNS------SCGEGYKLSGSVYQ 506
Query: 569 VCNRDGKWSYDIPSCELTSCPEPEV-----PSGGYMEAFDYYVHSTINFHCEAGHK---- 619
C W +I C+ +CP P V +G +E F Y +T+ + C G +
Sbjct: 507 ECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPY--GTTVTYTCNPGPERGVE 564
Query: 620 --LIGEPNLVC----QQDGEWSGDSPTCEY----IDCGKLPTLPYGTMELLNGTTHLGSV 669
LIGE + C Q+ G WSG +P C+ + C + +
Sbjct: 565 FSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDT 624
Query: 670 IQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHT 729
+ + C + + L G + C + W P CE+ C +S+ + R
Sbjct: 625 VTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKETCQH---VRQSLQELPAGSRVE--- 678
Query: 730 LIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCED--NGQWSGTTPTCQYVDCGN 787
L+ TS C+ GY++ G + C+D NG W P C+ + C
Sbjct: 679 LVNTS------------------CQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHP 720
Query: 788 PGRIENGKVT-LPSNATFYGATAFYQCDENWELEGVIRRMCQEN----GTWSLEPPICKE 842
P I NGK T + + YG Y+CD+ + L G + C+ + G+WS P C
Sbjct: 721 PPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLR 780
Query: 843 ---IT-CPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGT 898
+T CP+P ++K G L S S + C G+ + G + C + W
Sbjct: 781 SPPVTRCPNP--EVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPG 838
Query: 899 VPVCIP---IDCRSPGNIENGKIVISNGSTLF-GSSVEYYCLSQYQRVGPFLRKCLDDGR 954
VP CI I C P NG N + G S+ Y C Y VG L C +G
Sbjct: 839 VPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGT 898
Query: 955 WSGEEPSCE 963
WS P C+
Sbjct: 899 WSQPAPHCK 907
Score = 193 bits (470), Expect = 3e-48
Identities = 155/572 (27%), Positives = 230/572 (40%), Gaps = 71/572 (12%)
Query: 369 YDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNR 428
+D G+ I Y C G++L+G++S C + W+ P CK C E L+
Sbjct: 429 FDPGTSIKYSCNPGYVLVGEESIQCTSE-VWTPPVPQCKVAAC------EATGRQLLTKP 481
Query: 429 TTHGAR--ALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVT--- 483
R SC E + L G+ + C W E C CP PP + N + T
Sbjct: 482 QHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSS 541
Query: 484 VNGHKAGSLASYTCENG------HILSGSTSVTCTLG----GAWSGVPPSCKY----VNC 529
+ G+ +YTC G L G +++ CT G WSG P CK V C
Sbjct: 542 LEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQC 601
Query: 530 GTPTIHKGSFVLINGTTT---YGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELT 586
+H + I+G Y F C + L G+ ++ C D W +IP CE
Sbjct: 602 SH--VHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKE 659
Query: 587 SCPE-----PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQ--QDGEWSGDSP 639
+C E+P+G +E +N C+ G++L G +CQ ++G W P
Sbjct: 660 TCQHVRQSLQELPAGSRVEL--------VNTSCQDGYQLTGHAYQMCQDAENGIWFKKIP 711
Query: 640 TCEYIDCGKLPTLPYGTMELLNGTTHL-GSVIQYSCTTNYRLVGPVRRTCTEEFQ----W 694
C+ I C P + G + L G+ + Y C + L+G + C + + W
Sbjct: 712 LCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSW 771
Query: 695 SDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCE 754
S SP+C +R S P+ + HG+ L +T + Y +V C
Sbjct: 772 SGPSPQC--LR-SPPVTR------CPNPEVKHGYKLNKTH------SAYSHNDIVYVDCN 816
Query: 755 KGYKVIGESLSTCEDNGQWSGTTPTC---QYVDCGNPGRIENGKVTLPSNATFY-GATAF 810
G+ + G + C + W PTC ++ C P + NG T + A F G +
Sbjct: 817 PGFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSIL 876
Query: 811 YQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGE 870
Y CD+ + L G +C GTWS P CKE+ C P+ GL G
Sbjct: 877 YSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVNCSSPADMDGIQKGL-EPRKMYQYGAV 935
Query: 871 AHYQCERGYNLKGHQTRTCISKGQWNGTVPVC 902
+CE GY L+G C S QWN + VC
Sbjct: 936 VTLECEDGYMLEGSPQSQCQSDHQWNPPLAVC 967
Score = 171 bits (416), Expect = 1e-41
Identities = 158/612 (25%), Positives = 238/612 (38%), Gaps = 82/612 (13%)
Query: 404 PSCKYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTC----GDEGIW 459
P ++CG PI +G ++ G YSC F L+G C +G W
Sbjct: 16 PGVLGISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTW 75
Query: 460 DGEAPRC----LFDWCPDPPAVSNASVT-VNGHKAGSLASYTCENGHILSGSTSVTCTLG 514
D AP+C + CP+P + ++ G ++ C+ ++G+ SV C
Sbjct: 76 DKPAPKCEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQAN 135
Query: 515 GAWSGVP-PSCKYV---NC-GTPTIHKGSFVLIN-GTTTYGSIAQFTCEPDYWLNGAEEL 568
W P+C V C P IH G N G+ G ++CE Y L G + +
Sbjct: 136 NMWGPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKII 195
Query: 569 VCNRDGKWSYDIPSCELTSCPE-PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLV 627
C GKWS P+CE C P+G E V T NF C+ G++L G P+
Sbjct: 196 NCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSR 255
Query: 628 CQQDGE---WSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHL--GSVIQYSCT------T 676
C G+ W+ P CE I C P + G + N ++ GS++ Y+C
Sbjct: 256 CVIAGQGVAWT-KMPVCEEIFCPSPPPILNG-RHIGNSLANVSYGSIVTYTCDPDPEEGV 313
Query: 677 NYRLVGPVRRTCTEEFQ----WSDSSPRCE----EIRCSDPIVAEKSIVSVTGNDRSHGH 728
N+ L+G CT + Q WS +PRCE ++C P + +VS + ++
Sbjct: 314 NFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYTYND 373
Query: 729 TLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNP 788
T+I + C G+ + G C G W + P C+ +C P
Sbjct: 374 TVI-------------------FACMFGFTLKGSKQIRCNAQGTWEPSAPVCE-KECQAP 413
Query: 789 GRIENGKVTLPSNATFYGATAF-YQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPD 847
I NG+ F T+ Y C+ + L G C W+ P CK C
Sbjct: 414 PNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSE-VWTPPVPQCKVAACE- 471
Query: 848 PSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDC 907
G LL + + + C GY L G + C W + +C I C
Sbjct: 472 -----ATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITC 526
Query: 908 RSPGNIENGKIVISNGSTL----FGSSVEYYCLS------QYQRVGPFLRKCLDD----G 953
P I NG GS+L +G++V Y C ++ +G +C + G
Sbjct: 527 PPPPVIYNG---AHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERG 583
Query: 954 RWSGEEPSCELA 965
WSG P C+L+
Sbjct: 584 TWSGPAPLCKLS 595
Score = 166 bits (404), Expect = 3e-40
Identities = 159/642 (24%), Positives = 243/642 (37%), Gaps = 69/642 (10%)
Query: 353 CGSPDKLLNTTILGND--YDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVN 410
C P L + G Y +++ C G L G K C G W + P C+
Sbjct: 351 CPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEK-E 409
Query: 411 CGGLTPIEDG---DVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL 467
C I +G D ++ R G YSC + LVG C E +W P+C
Sbjct: 410 CQAPPNILNGQKEDRHMV--RFDPGTSIKYSCNPGYVLVGEESIQCTSE-VWTPPVPQCK 466
Query: 468 FDWCPDPPAVSNASVTVNGHK-AGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKY 526
C A +T H+ + +C G+ LSGS C W CK
Sbjct: 467 VAACE---ATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKE 523
Query: 527 VNCGTP-TIHKGSFVLIN-GTTTYGSIAQFTCEP------DYWLNGAEELVCNRD----G 574
+ C P I+ G+ + YG+ +TC P ++ L G + C + G
Sbjct: 524 ITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERG 583
Query: 575 KWSYDIPSCELT----SCPEPEVPSGGYMEAFD--YYVHSTINFHCEAGHKLIGEPNLVC 628
WS P C+L+ C + +G + + Y+ + T+ F C +G L G + C
Sbjct: 584 TWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRC 643
Query: 629 QQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTC 688
+ D W + P CE C + EL G+ ++ SC Y+L G + C
Sbjct: 644 KADNTWDPEIPVCEKETCQHVRQ---SLQELPAGSRV--ELVNTSCQDGYQLTGHAYQMC 698
Query: 689 --TEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIG 746
E W P C+ I C P V V G HT + ++N GN
Sbjct: 699 QDAENGIWFKKIPLCKVIHCHPPPVI------VNGK-----HTGMM-AENFLYGNE---- 742
Query: 747 ALVKYRCEKGYKVIGESLSTCEDN----GQWSGTTPTC----QYVDCGNPGRIENGKVTL 798
V Y C++G+ ++GE C + G WSG +P C C NP K+
Sbjct: 743 --VSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNK 800
Query: 799 PSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKE---ITCPDPSAQIKAG 855
+A + + C+ + + G C + TW P C + I CP P + G
Sbjct: 801 THSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPP-KTPNG 859
Query: 856 SGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIEN 915
+ + S G Y C++GY L G C +G W+ P C ++C SP +++
Sbjct: 860 NHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVNCSSPADMDG 919
Query: 916 -GKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWS 956
K + +G+ V C Y G +C D +W+
Sbjct: 920 IQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSDHQWN 961
Score = 152 bits (369), Expect = 6e-36
Identities = 123/465 (26%), Positives = 182/465 (39%), Gaps = 56/465 (12%)
Query: 352 TCGSPDKLLNTTILGN---DYDVGSRIVYKCPEG------HMLLGDKSRHCKKD----GF 398
TC P + N G+ D+ G+ + Y C G L+G+ + C + G
Sbjct: 525 TCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGT 584
Query: 399 WSGAPPSCKY----VNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCG 454
WSG P CK V C + ++ + + + C FTL G+ + C
Sbjct: 585 WSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCK 644
Query: 455 DEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTC--T 512
+ WD E P C + C V + + L + +C++G+ L+G C
Sbjct: 645 ADNTWDPEIPVCEKETCQH---VRQSLQELPAGSRVELVNTSCQDGYQLTGHAYQMCQDA 701
Query: 513 LGGAWSGVPPSCKYVNCGTP-TIHKGSFV-LINGTTTYGSIAQFTCEPDYWLNGAEELVC 570
G W P CK ++C P I G ++ YG+ + C+ ++L G ++L C
Sbjct: 702 ENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQC 761
Query: 571 NRD----GKWSYDIPSC----ELTSCPEPEVPSGGYM-EAFDYYVHSTINF-HCEAGHKL 620
D G WS P C +T CP PEV G + + Y H+ I + C G +
Sbjct: 762 RSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIM 821
Query: 621 IGEPNLVCQQDGEWSGDSPTC---EYIDCGKLPTLPYGTMELLN-GTTHLGSVIQYSCTT 676
G + C D W PTC +I C P P G N G I YSC
Sbjct: 822 NGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQ 881
Query: 677 NYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDN 736
Y LVG CT E WS +P C+E+ CS P + G +
Sbjct: 882 GYLLVGEALLLCTHEGTWSQPAPHCKEVNCSSP-------ADMDGIQK-----------G 923
Query: 737 RDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQ 781
+ Y+ GA+V CE GY + G S C+ + QW+ C+
Sbjct: 924 LEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSDHQWNPPLAVCR 968
Score = 137 bits (331), Expect = 2e-31
Identities = 129/520 (24%), Positives = 202/520 (38%), Gaps = 66/520 (12%)
Query: 379 CPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDG-DVALIDNRTTHGARALY 437
C EG+ L G + C+ W CK + C I +G +G Y
Sbjct: 494 CGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTY 553
Query: 438 SCREN------FTLVGNPERTCG----DEGIWDGEAPRCLFDWCPDPPAVSNASVTV-NG 486
+C F+L+G C + G W G AP C AV + V + NG
Sbjct: 554 TCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLL----AVQCSHVHIANG 609
Query: 487 HK-AGSLASY--------TCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTIHKG 537
+K +G A Y C +G L GS+ + C W P C+ C + +
Sbjct: 610 YKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKETC--QHVRQS 667
Query: 538 SFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCN--RDGKWSYDIPSCELTSC-PEPEVP 594
L G+ + +C+ Y L G +C +G W IP C++ C P P +
Sbjct: 668 LQELPAGSRV--ELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIV 725
Query: 595 SGGY--MEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQD----GEWSGDSPTC----EYI 644
+G + M A ++ + +++ C+ G L+GE L C+ D G WSG SP C
Sbjct: 726 NGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVT 785
Query: 645 DCGKLPTLPYG-TMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEE 703
C P + +G + + ++ C + + G C + W P C +
Sbjct: 786 RCPN-PEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPTCIK 844
Query: 704 ---IRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVI 760
I C P T N G + R S G + Y C++GY ++
Sbjct: 845 KAFIGCPPP--------PKTPNGNHTGGNIARFSP----------GMSILYSCDQGYLLV 886
Query: 761 GESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTL-PSNATFYGATAFYQCDENWEL 819
GE+L C G WS P C+ V+C +P ++ + L P YGA +C++ + L
Sbjct: 887 GEALLLCTHEGTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYML 946
Query: 820 EGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLL 859
EG + CQ + W+ +C+ + I AG LL
Sbjct: 947 EGSPQSQCQSDHQWNPPLAVCRSRSLAPVLCGIAAGLILL 986
Score = 108 bits (259), Expect = 1e-22
Identities = 71/256 (27%), Positives = 106/256 (41%), Gaps = 23/256 (8%)
Query: 353 CGSPDKLLN---TTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKD----GFWSGAPPS 405
C P ++N T ++ ++ G+ + Y+C +G LLG+K C+ D G WSG P
Sbjct: 718 CHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQ 777
Query: 406 CKYVNCGGLTPIEDGDVALIDNRT----THGARALYSCRENFTLVGNPERTCGDEGIWDG 461
C P + N+T +H C F + G+ C + W
Sbjct: 778 CLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVP 837
Query: 462 EAPRCL---FDWCPDPPAVSNASVT---VNGHKAGSLASYTCENGHILSGSTSVTCTLGG 515
P C+ F CP PP N + T + G Y+C+ G++L G + CT G
Sbjct: 838 GVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEG 897
Query: 516 AWSGVPPSCKYVNCGTPT----IHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCN 571
WS P CK VNC +P I KG + YG++ CE Y L G+ + C
Sbjct: 898 TWSQPAPHCKEVNCSSPADMDGIQKG--LEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQ 955
Query: 572 RDGKWSYDIPSCELTS 587
D +W+ + C S
Sbjct: 956 SDHQWNPPLAVCRSRS 971
Score = 40.3 bits (90), Expect = 0.037
Identities = 23/75 (30%), Positives = 29/75 (38%), Gaps = 1/75 (1%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTN 61
C P PN + N G +Y CD+GY L G CT G W+ P C
Sbjct: 850 CPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHC-KE 908
Query: 62 VAFRKPANQSTTVRG 76
V PA+ +G
Sbjct: 909 VNCSSPADMDGIQKG 923
Score = 38.7 bits (86), Expect = 0.11
Identities = 19/56 (33%), Positives = 25/56 (44%), Gaps = 2/56 (3%)
Query: 5 PAVPP--NARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
PA+P N + N +I G Y C+ GY L G + C G W+ PP C
Sbjct: 155 PALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTC 210
Score = 36.3 bits (80), Expect = 0.60
Identities = 19/61 (31%), Positives = 28/61 (45%), Gaps = 4/61 (6%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTL----RGDWTLEPPF 57
C P V N + + EN + G YECD+G+ L G ++ +C G W+ P
Sbjct: 718 CHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQ 777
Query: 58 C 58
C
Sbjct: 778 C 778
Score = 34.7 bits (76), Expect = 1.8
Identities = 16/58 (27%), Positives = 26/58 (44%), Gaps = 1/58 (1%)
Query: 1 RCGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
+C HP + VS + T+ ++ C G+ L G++Q C +G W P C
Sbjct: 350 QCPHPQILRGRMVSGQKDRYTYNDTV-IFACMFGFTLKGSKQIRCNAQGTWEPSAPVC 406
>Z99572-8|CAI23064.1| 753|Homo sapiens selectin P (granule membrane
protein 140kDa, antigen CD62) protein.
Length = 753
Score = 217 bits (529), Expect = 2e-55
Identities = 178/703 (25%), Positives = 282/703 (40%), Gaps = 91/703 (12%)
Query: 236 SFDEARKQCQSHGGDLIHGFQGATSSFLTQELERRKAQLKTQLVWIGAQKEPGLTSRTWQ 295
S++ +RK CQ+ DL+ +L + L + WIG +K ++TW
Sbjct: 37 SWNISRKYCQNRYTDLVAIQNKNEIDYLNKVLP-----YYSSYYWIGIRKN----NKTWT 87
Query: 296 WVDGELV---SKPSWGKDQPNNYNGEQNCV---VLDGGRGWLWNDVGCNLDYLHWICQYL 349
WV + +W ++PNN ++CV + WND C L H +C
Sbjct: 88 WVGTKKALTNEAENWADNEPNNKRNNEDCVEIYIKSPSAPGKWNDEHC-LKKKHALCY-- 144
Query: 350 PPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYV 409
T D ++ + G +C E +G+ + C GF+ P C+YV
Sbjct: 145 --TASCQD--MSCSKQG-----------ECLE---TIGNYTCSCYP-GFYG---PECEYV 182
Query: 410 N-CGGLTPIEDGDVALID--NRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRC 466
CG L + + + ++ + C + + + G + C GIW + P+C
Sbjct: 183 RECGELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQC 242
Query: 467 LFDWCPDPPAVSNASVT-VNGHKA---GSLASYTCENGHILSGSTSVTCTLGGAWSGVPP 522
L CP ++T ++ KA S S++CE G L G V CT G W+ P
Sbjct: 243 LAAQCPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASGVWTAPAP 302
Query: 523 SCKYVNCGT--PTIHKGSFVLINGTTT--YGSIAQFTCEPDYWLNGAEELVCNRDGKWSY 578
CK ++C +H GS Y + F C + L GA+ + C+ G+W+
Sbjct: 303 VCKAISCEPLESPVH-GSMDCSPSLRAFQYDTNCSFRCAEGFMLRGADIVRCDNLGQWTA 361
Query: 579 DIPSCELTSCPEPEVPSGGYME------AFDYYVHSTINFHCEAGHKLIGEPNLVCQQDG 632
P C+ C + VP+ + AF Y S +F C G L+G L C G
Sbjct: 362 PAPVCQALQCQDLPVPNEARVNCSHPFGAFRY--QSVCSFTCNEGLLLVGASVLQCLATG 419
Query: 633 EWSGDSPTCEYIDCGKLPTLPYGTMELLN--GTTHLGSVIQYSCTTNYRLVGPVRRTCTE 690
W+ P C+ I C L + GTM + G++ S Q+ C Y L GP R CT
Sbjct: 420 NWNSVPPECQAIPCTPLLSPQNGTMTCVQPLGSSSYKSTCQFICDEGYSLSGPERLDCTR 479
Query: 691 EFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVK 750
+W+DS P CE I+C + E+ + D D + +G+
Sbjct: 480 SGRWTDSPPMCEAIKCPELFAPEQG-----------------SLDCSDTRGEFNVGSTCH 522
Query: 751 YRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYV-DCGNPGRIENGKVTLPSNATFY---- 805
+ C+ G+K+ G + C +G+WS T PTC+ + PG ++ +T P T Y
Sbjct: 523 FSCDNGFKLEGPNNVECTTSGRWSATPPTCKGIASLPTPG-VQCPALTTPGQGTMYCRHH 581
Query: 806 ------GATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLL 859
T ++ C+ + L G C+ +G W+ P C+ + C +
Sbjct: 582 PGTFGFNTTCYFGCNAGFTLIGDSTLSCRPSGQWTAVTPACRAVKCSELHVNKPIAMNCS 641
Query: 860 VVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVC 902
+ S G + C G L G C G W+ TVP C
Sbjct: 642 NLWGNFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTC 684
Score = 208 bits (509), Expect = 6e-53
Identities = 128/430 (29%), Positives = 191/430 (44%), Gaps = 44/430 (10%)
Query: 377 YKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGL-TPIEDG-DVALIDNRTTHGAR 434
+ C EG L+G + C G W+ P CK ++C L +P+ D + +
Sbjct: 275 FSCEEGFALVGPEVVQCTASGVWTAPAPVCKAISCEPLESPVHGSMDCSPSLRAFQYDTN 334
Query: 435 ALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAG---- 490
+ C E F L G C + G W AP C C D P + A V + H G
Sbjct: 335 CSFRCAEGFMLRGADIVRCDNLGQWTAPAPVCQALQCQDLPVPNEARVNCS-HPFGAFRY 393
Query: 491 -SLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTI--HKGSFVLIN--GT 545
S+ S+TC G +L G++ + C G W+ VPP C+ + C TP + G+ + G+
Sbjct: 394 QSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPECQAIPC-TPLLSPQNGTMTCVQPLGS 452
Query: 546 TTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFD-- 603
++Y S QF C+ Y L+G E L C R G+W+ P CE CPE P G ++ D
Sbjct: 453 SSYKSTCQFICDEGYSLSGPERLDCTRSGRWTDSPPMCEAIKCPELFAPEQGSLDCSDTR 512
Query: 604 --YYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYI--------DCGKLPTLP 653
+ V ST +F C+ G KL G N+ C G WS PTC+ I C L T
Sbjct: 513 GEFNVGSTCHFSCDNGFKLEGPNNVECTTSGRWSATPPTCKGIASLPTPGVQCPALTTPG 572
Query: 654 YGTMELLN--GTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIV 711
GTM + GT + + C + L+G +C QW+ +P C ++CS+ +
Sbjct: 573 QGTMYCRHHPGTFGFNTTCYFGCNAGFTLIGDSTLSCRPSGQWTAVTPACRAVKCSE-LH 631
Query: 712 AEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNG 771
K I N + + G++ + C +G + G + + C++NG
Sbjct: 632 VNKPIAMNCSN----------------LWGNFSYGSICSFHCLEGQLLNGSAQTACQENG 675
Query: 772 QWSGTTPTCQ 781
WS T PTCQ
Sbjct: 676 HWSTTVPTCQ 685
Score = 191 bits (465), Expect = 1e-47
Identities = 127/508 (25%), Positives = 206/508 (40%), Gaps = 42/508 (8%)
Query: 479 NASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTI-HKG 537
N S + S S+ C +G+ ++G + + C G W+ PP C C I +G
Sbjct: 197 NCSHPLGNFSFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQCLAAQCPPLKIPERG 256
Query: 538 SFVLINGTTTYG--SIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPS 595
+ ++ + S F+CE + L G E + C G W+ P C+ SC E P
Sbjct: 257 NMTCLHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASGVWTAPAPVCKAISCEPLESPV 316
Query: 596 GGYME------AFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKL 649
G M+ AF Y + +F C G L G + C G+W+ +P C+ + C L
Sbjct: 317 HGSMDCSPSLRAFQY--DTNCSFRCAEGFMLRGADIVRCDNLGQWTAPAPVCQALQCQDL 374
Query: 650 PTLPYGTMELLN--GTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCS 707
P + + G SV ++C LVG C W+ P C+ I C+
Sbjct: 375 PVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPECQAIPCT 434
Query: 708 DPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTC 767
P+++ ++ T ++ + +T ++ C++GY + G C
Sbjct: 435 -PLLSPQNGTM----------TCVQPLGSSSYKST------CQFICDEGYSLSGPERLDC 477
Query: 768 EDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFY--GATAFYQCDENWELEGVIRR 825
+G+W+ + P C+ + C E G + + G+T + CD ++LEG
Sbjct: 478 TRSGRWTDSPPMCEAIKCPELFAPEQGSLDCSDTRGEFNVGSTCHFSCDNGFKLEGPNNV 537
Query: 826 MCQENGTWSLEPPICKEI-TCPDPSAQIKA----GSGLLVVT---STLSIGGEAHYQCER 877
C +G WS PP CK I + P P Q A G G + T ++ C
Sbjct: 538 ECTTSGRWSATPPTCKGIASLPTPGVQCPALTTPGQGTMYCRHHPGTFGFNTTCYFGCNA 597
Query: 878 GYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISN--GSTLFGSSVEYYC 935
G+ L G T +C GQW P C + C + + SN G+ +GS ++C
Sbjct: 598 GFTLIGDSTLSCRPSGQWTAVTPACRAVKCSELHVNKPIAMNCSNLWGNFSYGSICSFHC 657
Query: 936 LSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
L G C ++G WS P+C+
Sbjct: 658 LEGQLLNGSAQTACQENGHWSTTVPTCQ 685
Score = 188 bits (457), Expect = 1e-46
Identities = 123/489 (25%), Positives = 204/489 (41%), Gaps = 45/489 (9%)
Query: 498 ENGHILSGSTSVTCTLGGAWSGVPPSCKYVN-CGTPTIHKGSFVLIN-----GTTTYGSI 551
+ G L + TC+ + G P C+YV CG + VL+N G ++ S
Sbjct: 155 KQGECLETIGNYTCSCYPGFYG--PECEYVRECGE--LELPQHVLMNCSHPLGNFSFNSQ 210
Query: 552 AQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYM----EAFDYYVH 607
F C Y +NG +L C G W+ P C CP ++P G M A +
Sbjct: 211 CSFHCTDGYQVNGPSKLECLASGIWTNKPPQCLAAQCPPLKIPERGNMTCLHSAKAFQHQ 270
Query: 608 STINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTT--H 665
S+ +F CE G L+G + C G W+ +P C+ I C L + +G+M+
Sbjct: 271 SSCSFSCEEGFALVGPEVVQCTASGVWTAPAPVCKAISCEPLESPVHGSMDCSPSLRAFQ 330
Query: 666 LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRS 725
+ + C + L G C QW+ +P C+ ++C D V ++ V+ S
Sbjct: 331 YDTNCSFRCAEGFMLRGADIVRCDNLGQWTAPAPVCQALQCQDLPVPNEARVNC-----S 385
Query: 726 HGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDC 785
H +R ++ + C +G ++G S+ C G W+ P CQ + C
Sbjct: 386 HPF------------GAFRYQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPECQAIPC 433
Query: 786 GNPGRIENGKVTL--PSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEI 843
+NG +T P ++ Y +T + CDE + L G R C +G W+ PP+C+ I
Sbjct: 434 TPLLSPQNGTMTCVQPLGSSSYKSTCQFICDEGYSLSGPERLDCTRSGRWTDSPPMCEAI 493
Query: 844 TCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVC- 902
CP+ A + ++G H+ C+ G+ L+G C + G+W+ T P C
Sbjct: 494 KCPELFAPEQGSLDCSDTRGEFNVGSTCHFSCDNGFKLEGPNNVECTTSGRWSATPPTCK 553
Query: 903 ----IP---IDCRSPGNIENGKIVISNGSTLFGSSVEYY--CLSQYQRVGPFLRKCLDDG 953
+P + C + G + + FG + Y C + + +G C G
Sbjct: 554 GIASLPTPGVQCPALTTPGQGTMYCRHHPGTFGFNTTCYFGCNAGFTLIGDSTLSCRPSG 613
Query: 954 RWSGEEPSC 962
+W+ P+C
Sbjct: 614 QWTAVTPAC 622
Score = 109 bits (262), Expect = 5e-23
Identities = 74/259 (28%), Positives = 109/259 (42%), Gaps = 21/259 (8%)
Query: 346 CQYLPPT-CGSPDKLLNTTI--LGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGA 402
CQ +P T SP T + LG+ S + C EG+ L G + C + G W+ +
Sbjct: 428 CQAIPCTPLLSPQNGTMTCVQPLGSS-SYKSTCQFICDEGYSLSGPERLDCTRSGRWTDS 486
Query: 403 PPSCKYVNCGGLTPIEDGDVALIDNRTTH--GARALYSCRENFTLVGNPERTCGDEGIWD 460
PP C+ + C L E G + D R G+ +SC F L G C G W
Sbjct: 487 PPMCEAIKCPELFAPEQGSLDCSDTRGEFNVGSTCHFSCDNGFKLEGPNNVECTTSGRWS 546
Query: 461 GEAPRCLFDWCPDPPAVSNASVTVNG-------HKAGSLASYT-----CENGHILSGSTS 508
P C P V ++T G H G+ T C G L G ++
Sbjct: 547 ATPPTCKGIASLPTPGVQCPALTTPGQGTMYCRHHPGTFGFNTTCYFGCNAGFTLIGDST 606
Query: 509 VTCTLGGAWSGVPPSCKYVNCGTPTIHKGSFVLIN---GTTTYGSIAQFTCEPDYWLNGA 565
++C G W+ V P+C+ V C ++K + + G +YGSI F C LNG+
Sbjct: 607 LSCRPSGQWTAVTPACRAVKCSELHVNKPIAMNCSNLWGNFSYGSICSFHCLEGQLLNGS 666
Query: 566 EELVCNRDGKWSYDIPSCE 584
+ C +G WS +P+C+
Sbjct: 667 AQTACQENGHWSTTVPTCQ 685
Score = 97.5 bits (232), Expect = 2e-19
Identities = 59/240 (24%), Positives = 97/240 (40%), Gaps = 7/240 (2%)
Query: 728 HTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGN 787
H L+ S +GN + + + C GY+V G S C +G W+ P C C
Sbjct: 193 HVLMNCS--HPLGN-FSFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQCLAAQCPP 249
Query: 788 PGRIENGKVT-LPSNATF-YGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITC 845
E G +T L S F + ++ + C+E + L G C +G W+ P+CK I+C
Sbjct: 250 LKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASGVWTAPAPVCKAISC 309
Query: 846 PDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPI 905
+ + ++C G+ L+G C + GQW PVC +
Sbjct: 310 EPLESPVHGSMDCSPSLRAFQYDTNCSFRCAEGFMLRGADIVRCDNLGQWTAPAPVCQAL 369
Query: 906 DCRSPGNIENGKIVISN--GSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
C+ ++ S+ G+ + S + C VG + +CL G W+ P C+
Sbjct: 370 QCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPECQ 429
Score = 73.3 bits (172), Expect = 4e-12
Identities = 44/192 (22%), Positives = 76/192 (39%), Gaps = 7/192 (3%)
Query: 778 PTCQYV-DCGN---PGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTW 833
P C+YV +CG P + N +F +F+ C + +++ G + C +G W
Sbjct: 177 PECEYVRECGELELPQHVLMNCSHPLGNFSFNSQCSFH-CTDGYQVNGPSKLECLASGIW 235
Query: 834 SLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKG 893
+ +PP C CP + L + CE G+ L G + C + G
Sbjct: 236 TNKPPQCLAAQCPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASG 295
Query: 894 QWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLF--GSSVEYYCLSQYQRVGPFLRKCLD 951
W PVC I C + +G + S F ++ + C + G + +C +
Sbjct: 296 VWTAPAPVCKAISCEPLESPVHGSMDCSPSLRAFQYDTNCSFRCAEGFMLRGADIVRCDN 355
Query: 952 DGRWSGEEPSCE 963
G+W+ P C+
Sbjct: 356 LGQWTAPAPVCQ 367
Score = 54.8 bits (126), Expect = 2e-06
Identities = 27/109 (24%), Positives = 45/109 (41%), Gaps = 2/109 (1%)
Query: 866 SIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGST 925
S + + C GY + G C++ G W P C+ C E G + + +
Sbjct: 206 SFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQCLAAQCPPLKIPERGNMTCLHSAK 265
Query: 926 LFG--SSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCELATNEAVDS 972
F SS + C + VGP + +C G W+ P C+ + E ++S
Sbjct: 266 AFQHQSSCSFSCEEGFALVGPEVVQCTASGVWTAPAPVCKAISCEPLES 314
Score = 40.7 bits (91), Expect = 0.028
Identities = 15/28 (53%), Positives = 17/28 (60%)
Query: 31 CDEGYELFGARQRECTLRGDWTLEPPFC 58
CDEGY L G + +CT G WT PP C
Sbjct: 463 CDEGYSLSGPERLDCTRSGRWTDSPPMC 490
Score = 38.7 bits (86), Expect = 0.11
Identities = 14/35 (40%), Positives = 19/35 (54%)
Query: 24 GTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
G+ + CD G++L G ECT G W+ PP C
Sbjct: 518 GSTCHFSCDNGFKLEGPNNVECTTSGRWSATPPTC 552
Score = 35.9 bits (79), Expect = 0.79
Identities = 16/58 (27%), Positives = 28/58 (48%), Gaps = 1/58 (1%)
Query: 2 CGHPAVPPNARVSIPNE-ENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
CG +P + ++ + N + + C +GY++ G + EC G WT +PP C
Sbjct: 185 CGELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQC 242
Score = 34.7 bits (76), Expect = 1.8
Identities = 18/59 (30%), Positives = 27/59 (45%), Gaps = 1/59 (1%)
Query: 1 RCGHPAVPPNARVSIPNEENIVA-GTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
+C VP ARV+ + ++ + C+EG L GA +C G+W PP C
Sbjct: 370 QCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPEC 428
Score = 34.3 bits (75), Expect = 2.4
Identities = 12/30 (40%), Positives = 16/30 (53%)
Query: 29 YECDEGYELFGARQRECTLRGDWTLEPPFC 58
+ C+EG+ L G +CT G WT P C
Sbjct: 275 FSCEEGFALVGPEVVQCTASGVWTAPAPVC 304
Score = 32.3 bits (70), Expect = 9.7
Identities = 20/62 (32%), Positives = 27/62 (43%), Gaps = 3/62 (4%)
Query: 20 NIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTNVAFRKPANQSTTVRGGAA 79
N G+I + C EG L G+ Q C G W+ P C A ++ T GGA
Sbjct: 646 NFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTC---QAGPLTIQEALTYFGGAV 702
Query: 80 AN 81
A+
Sbjct: 703 AS 704
>Z99572-2|CAI23061.1| 768|Homo sapiens selectin P (granule membrane
protein 140kDa, antigen CD62) protein.
Length = 768
Score = 217 bits (529), Expect = 2e-55
Identities = 178/703 (25%), Positives = 282/703 (40%), Gaps = 91/703 (12%)
Query: 236 SFDEARKQCQSHGGDLIHGFQGATSSFLTQELERRKAQLKTQLVWIGAQKEPGLTSRTWQ 295
S++ +RK CQ+ DL+ +L + L + WIG +K ++TW
Sbjct: 52 SWNISRKYCQNRYTDLVAIQNKNEIDYLNKVLP-----YYSSYYWIGIRKN----NKTWT 102
Query: 296 WVDGELV---SKPSWGKDQPNNYNGEQNCV---VLDGGRGWLWNDVGCNLDYLHWICQYL 349
WV + +W ++PNN ++CV + WND C L H +C
Sbjct: 103 WVGTKKALTNEAENWADNEPNNKRNNEDCVEIYIKSPSAPGKWNDEHC-LKKKHALCY-- 159
Query: 350 PPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYV 409
T D ++ + G +C E +G+ + C GF+ P C+YV
Sbjct: 160 --TASCQD--MSCSKQG-----------ECLE---TIGNYTCSCYP-GFYG---PECEYV 197
Query: 410 N-CGGLTPIEDGDVALID--NRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRC 466
CG L + + + ++ + C + + + G + C GIW + P+C
Sbjct: 198 RECGELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQC 257
Query: 467 LFDWCPDPPAVSNASVT-VNGHKA---GSLASYTCENGHILSGSTSVTCTLGGAWSGVPP 522
L CP ++T ++ KA S S++CE G L G V CT G W+ P
Sbjct: 258 LAAQCPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASGVWTAPAP 317
Query: 523 SCKYVNCGT--PTIHKGSFVLINGTTT--YGSIAQFTCEPDYWLNGAEELVCNRDGKWSY 578
CK ++C +H GS Y + F C + L GA+ + C+ G+W+
Sbjct: 318 VCKAISCEPLESPVH-GSMDCSPSLRAFQYDTNCSFRCAEGFMLRGADIVRCDNLGQWTA 376
Query: 579 DIPSCELTSCPEPEVPSGGYME------AFDYYVHSTINFHCEAGHKLIGEPNLVCQQDG 632
P C+ C + VP+ + AF Y S +F C G L+G L C G
Sbjct: 377 PAPVCQALQCQDLPVPNEARVNCSHPFGAFRY--QSVCSFTCNEGLLLVGASVLQCLATG 434
Query: 633 EWSGDSPTCEYIDCGKLPTLPYGTMELLN--GTTHLGSVIQYSCTTNYRLVGPVRRTCTE 690
W+ P C+ I C L + GTM + G++ S Q+ C Y L GP R CT
Sbjct: 435 NWNSVPPECQAIPCTPLLSPQNGTMTCVQPLGSSSYKSTCQFICDEGYSLSGPERLDCTR 494
Query: 691 EFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVK 750
+W+DS P CE I+C + E+ + D D + +G+
Sbjct: 495 SGRWTDSPPMCEAIKCPELFAPEQG-----------------SLDCSDTRGEFNVGSTCH 537
Query: 751 YRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYV-DCGNPGRIENGKVTLPSNATFY---- 805
+ C+ G+K+ G + C +G+WS T PTC+ + PG ++ +T P T Y
Sbjct: 538 FSCDNGFKLEGPNNVECTTSGRWSATPPTCKGIASLPTPG-VQCPALTTPGQGTMYCRHH 596
Query: 806 ------GATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLL 859
T ++ C+ + L G C+ +G W+ P C+ + C +
Sbjct: 597 PGTFGFNTTCYFGCNAGFTLIGDSTLSCRPSGQWTAVTPACRAVKCSELHVNKPIAMNCS 656
Query: 860 VVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVC 902
+ S G + C G L G C G W+ TVP C
Sbjct: 657 NLWGNFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTC 699
Score = 208 bits (509), Expect = 6e-53
Identities = 128/430 (29%), Positives = 191/430 (44%), Gaps = 44/430 (10%)
Query: 377 YKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGL-TPIEDG-DVALIDNRTTHGAR 434
+ C EG L+G + C G W+ P CK ++C L +P+ D + +
Sbjct: 290 FSCEEGFALVGPEVVQCTASGVWTAPAPVCKAISCEPLESPVHGSMDCSPSLRAFQYDTN 349
Query: 435 ALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAG---- 490
+ C E F L G C + G W AP C C D P + A V + H G
Sbjct: 350 CSFRCAEGFMLRGADIVRCDNLGQWTAPAPVCQALQCQDLPVPNEARVNCS-HPFGAFRY 408
Query: 491 -SLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTI--HKGSFVLIN--GT 545
S+ S+TC G +L G++ + C G W+ VPP C+ + C TP + G+ + G+
Sbjct: 409 QSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPECQAIPC-TPLLSPQNGTMTCVQPLGS 467
Query: 546 TTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFD-- 603
++Y S QF C+ Y L+G E L C R G+W+ P CE CPE P G ++ D
Sbjct: 468 SSYKSTCQFICDEGYSLSGPERLDCTRSGRWTDSPPMCEAIKCPELFAPEQGSLDCSDTR 527
Query: 604 --YYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYI--------DCGKLPTLP 653
+ V ST +F C+ G KL G N+ C G WS PTC+ I C L T
Sbjct: 528 GEFNVGSTCHFSCDNGFKLEGPNNVECTTSGRWSATPPTCKGIASLPTPGVQCPALTTPG 587
Query: 654 YGTMELLN--GTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIV 711
GTM + GT + + C + L+G +C QW+ +P C ++CS+ +
Sbjct: 588 QGTMYCRHHPGTFGFNTTCYFGCNAGFTLIGDSTLSCRPSGQWTAVTPACRAVKCSE-LH 646
Query: 712 AEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNG 771
K I N + + G++ + C +G + G + + C++NG
Sbjct: 647 VNKPIAMNCSN----------------LWGNFSYGSICSFHCLEGQLLNGSAQTACQENG 690
Query: 772 QWSGTTPTCQ 781
WS T PTCQ
Sbjct: 691 HWSTTVPTCQ 700
Score = 191 bits (465), Expect = 1e-47
Identities = 127/508 (25%), Positives = 206/508 (40%), Gaps = 42/508 (8%)
Query: 479 NASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTI-HKG 537
N S + S S+ C +G+ ++G + + C G W+ PP C C I +G
Sbjct: 212 NCSHPLGNFSFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQCLAAQCPPLKIPERG 271
Query: 538 SFVLINGTTTYG--SIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPS 595
+ ++ + S F+CE + L G E + C G W+ P C+ SC E P
Sbjct: 272 NMTCLHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASGVWTAPAPVCKAISCEPLESPV 331
Query: 596 GGYME------AFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKL 649
G M+ AF Y + +F C G L G + C G+W+ +P C+ + C L
Sbjct: 332 HGSMDCSPSLRAFQY--DTNCSFRCAEGFMLRGADIVRCDNLGQWTAPAPVCQALQCQDL 389
Query: 650 PTLPYGTMELLN--GTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCS 707
P + + G SV ++C LVG C W+ P C+ I C+
Sbjct: 390 PVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPECQAIPCT 449
Query: 708 DPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTC 767
P+++ ++ T ++ + +T ++ C++GY + G C
Sbjct: 450 -PLLSPQNGTM----------TCVQPLGSSSYKST------CQFICDEGYSLSGPERLDC 492
Query: 768 EDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFY--GATAFYQCDENWELEGVIRR 825
+G+W+ + P C+ + C E G + + G+T + CD ++LEG
Sbjct: 493 TRSGRWTDSPPMCEAIKCPELFAPEQGSLDCSDTRGEFNVGSTCHFSCDNGFKLEGPNNV 552
Query: 826 MCQENGTWSLEPPICKEI-TCPDPSAQIKA----GSGLLVVT---STLSIGGEAHYQCER 877
C +G WS PP CK I + P P Q A G G + T ++ C
Sbjct: 553 ECTTSGRWSATPPTCKGIASLPTPGVQCPALTTPGQGTMYCRHHPGTFGFNTTCYFGCNA 612
Query: 878 GYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISN--GSTLFGSSVEYYC 935
G+ L G T +C GQW P C + C + + SN G+ +GS ++C
Sbjct: 613 GFTLIGDSTLSCRPSGQWTAVTPACRAVKCSELHVNKPIAMNCSNLWGNFSYGSICSFHC 672
Query: 936 LSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
L G C ++G WS P+C+
Sbjct: 673 LEGQLLNGSAQTACQENGHWSTTVPTCQ 700
Score = 188 bits (457), Expect = 1e-46
Identities = 123/489 (25%), Positives = 204/489 (41%), Gaps = 45/489 (9%)
Query: 498 ENGHILSGSTSVTCTLGGAWSGVPPSCKYVN-CGTPTIHKGSFVLIN-----GTTTYGSI 551
+ G L + TC+ + G P C+YV CG + VL+N G ++ S
Sbjct: 170 KQGECLETIGNYTCSCYPGFYG--PECEYVRECGE--LELPQHVLMNCSHPLGNFSFNSQ 225
Query: 552 AQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYM----EAFDYYVH 607
F C Y +NG +L C G W+ P C CP ++P G M A +
Sbjct: 226 CSFHCTDGYQVNGPSKLECLASGIWTNKPPQCLAAQCPPLKIPERGNMTCLHSAKAFQHQ 285
Query: 608 STINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTT--H 665
S+ +F CE G L+G + C G W+ +P C+ I C L + +G+M+
Sbjct: 286 SSCSFSCEEGFALVGPEVVQCTASGVWTAPAPVCKAISCEPLESPVHGSMDCSPSLRAFQ 345
Query: 666 LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRS 725
+ + C + L G C QW+ +P C+ ++C D V ++ V+ S
Sbjct: 346 YDTNCSFRCAEGFMLRGADIVRCDNLGQWTAPAPVCQALQCQDLPVPNEARVNC-----S 400
Query: 726 HGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDC 785
H +R ++ + C +G ++G S+ C G W+ P CQ + C
Sbjct: 401 HPF------------GAFRYQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPECQAIPC 448
Query: 786 GNPGRIENGKVTL--PSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEI 843
+NG +T P ++ Y +T + CDE + L G R C +G W+ PP+C+ I
Sbjct: 449 TPLLSPQNGTMTCVQPLGSSSYKSTCQFICDEGYSLSGPERLDCTRSGRWTDSPPMCEAI 508
Query: 844 TCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVC- 902
CP+ A + ++G H+ C+ G+ L+G C + G+W+ T P C
Sbjct: 509 KCPELFAPEQGSLDCSDTRGEFNVGSTCHFSCDNGFKLEGPNNVECTTSGRWSATPPTCK 568
Query: 903 ----IP---IDCRSPGNIENGKIVISNGSTLFGSSVEYY--CLSQYQRVGPFLRKCLDDG 953
+P + C + G + + FG + Y C + + +G C G
Sbjct: 569 GIASLPTPGVQCPALTTPGQGTMYCRHHPGTFGFNTTCYFGCNAGFTLIGDSTLSCRPSG 628
Query: 954 RWSGEEPSC 962
+W+ P+C
Sbjct: 629 QWTAVTPAC 637
Score = 109 bits (262), Expect = 5e-23
Identities = 74/259 (28%), Positives = 109/259 (42%), Gaps = 21/259 (8%)
Query: 346 CQYLPPT-CGSPDKLLNTTI--LGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGA 402
CQ +P T SP T + LG+ S + C EG+ L G + C + G W+ +
Sbjct: 443 CQAIPCTPLLSPQNGTMTCVQPLGSS-SYKSTCQFICDEGYSLSGPERLDCTRSGRWTDS 501
Query: 403 PPSCKYVNCGGLTPIEDGDVALIDNRTTH--GARALYSCRENFTLVGNPERTCGDEGIWD 460
PP C+ + C L E G + D R G+ +SC F L G C G W
Sbjct: 502 PPMCEAIKCPELFAPEQGSLDCSDTRGEFNVGSTCHFSCDNGFKLEGPNNVECTTSGRWS 561
Query: 461 GEAPRCLFDWCPDPPAVSNASVTVNG-------HKAGSLASYT-----CENGHILSGSTS 508
P C P V ++T G H G+ T C G L G ++
Sbjct: 562 ATPPTCKGIASLPTPGVQCPALTTPGQGTMYCRHHPGTFGFNTTCYFGCNAGFTLIGDST 621
Query: 509 VTCTLGGAWSGVPPSCKYVNCGTPTIHKGSFVLIN---GTTTYGSIAQFTCEPDYWLNGA 565
++C G W+ V P+C+ V C ++K + + G +YGSI F C LNG+
Sbjct: 622 LSCRPSGQWTAVTPACRAVKCSELHVNKPIAMNCSNLWGNFSYGSICSFHCLEGQLLNGS 681
Query: 566 EELVCNRDGKWSYDIPSCE 584
+ C +G WS +P+C+
Sbjct: 682 AQTACQENGHWSTTVPTCQ 700
Score = 97.5 bits (232), Expect = 2e-19
Identities = 59/240 (24%), Positives = 97/240 (40%), Gaps = 7/240 (2%)
Query: 728 HTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGN 787
H L+ S +GN + + + C GY+V G S C +G W+ P C C
Sbjct: 208 HVLMNCS--HPLGN-FSFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQCLAAQCPP 264
Query: 788 PGRIENGKVT-LPSNATF-YGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITC 845
E G +T L S F + ++ + C+E + L G C +G W+ P+CK I+C
Sbjct: 265 LKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASGVWTAPAPVCKAISC 324
Query: 846 PDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPI 905
+ + ++C G+ L+G C + GQW PVC +
Sbjct: 325 EPLESPVHGSMDCSPSLRAFQYDTNCSFRCAEGFMLRGADIVRCDNLGQWTAPAPVCQAL 384
Query: 906 DCRSPGNIENGKIVISN--GSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
C+ ++ S+ G+ + S + C VG + +CL G W+ P C+
Sbjct: 385 QCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPECQ 444
Score = 73.3 bits (172), Expect = 4e-12
Identities = 44/192 (22%), Positives = 76/192 (39%), Gaps = 7/192 (3%)
Query: 778 PTCQYV-DCGN---PGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTW 833
P C+YV +CG P + N +F +F+ C + +++ G + C +G W
Sbjct: 192 PECEYVRECGELELPQHVLMNCSHPLGNFSFNSQCSFH-CTDGYQVNGPSKLECLASGIW 250
Query: 834 SLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKG 893
+ +PP C CP + L + CE G+ L G + C + G
Sbjct: 251 TNKPPQCLAAQCPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASG 310
Query: 894 QWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLF--GSSVEYYCLSQYQRVGPFLRKCLD 951
W PVC I C + +G + S F ++ + C + G + +C +
Sbjct: 311 VWTAPAPVCKAISCEPLESPVHGSMDCSPSLRAFQYDTNCSFRCAEGFMLRGADIVRCDN 370
Query: 952 DGRWSGEEPSCE 963
G+W+ P C+
Sbjct: 371 LGQWTAPAPVCQ 382
Score = 54.8 bits (126), Expect = 2e-06
Identities = 27/109 (24%), Positives = 45/109 (41%), Gaps = 2/109 (1%)
Query: 866 SIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGST 925
S + + C GY + G C++ G W P C+ C E G + + +
Sbjct: 221 SFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQCLAAQCPPLKIPERGNMTCLHSAK 280
Query: 926 LFG--SSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCELATNEAVDS 972
F SS + C + VGP + +C G W+ P C+ + E ++S
Sbjct: 281 AFQHQSSCSFSCEEGFALVGPEVVQCTASGVWTAPAPVCKAISCEPLES 329
Score = 40.7 bits (91), Expect = 0.028
Identities = 15/28 (53%), Positives = 17/28 (60%)
Query: 31 CDEGYELFGARQRECTLRGDWTLEPPFC 58
CDEGY L G + +CT G WT PP C
Sbjct: 478 CDEGYSLSGPERLDCTRSGRWTDSPPMC 505
Score = 38.7 bits (86), Expect = 0.11
Identities = 14/35 (40%), Positives = 19/35 (54%)
Query: 24 GTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
G+ + CD G++L G ECT G W+ PP C
Sbjct: 533 GSTCHFSCDNGFKLEGPNNVECTTSGRWSATPPTC 567
Score = 35.9 bits (79), Expect = 0.79
Identities = 16/58 (27%), Positives = 28/58 (48%), Gaps = 1/58 (1%)
Query: 2 CGHPAVPPNARVSIPNE-ENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
CG +P + ++ + N + + C +GY++ G + EC G WT +PP C
Sbjct: 200 CGELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQC 257
Score = 34.7 bits (76), Expect = 1.8
Identities = 18/59 (30%), Positives = 27/59 (45%), Gaps = 1/59 (1%)
Query: 1 RCGHPAVPPNARVSIPNEENIVA-GTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
+C VP ARV+ + ++ + C+EG L GA +C G+W PP C
Sbjct: 385 QCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPEC 443
Score = 34.3 bits (75), Expect = 2.4
Identities = 12/30 (40%), Positives = 16/30 (53%)
Query: 29 YECDEGYELFGARQRECTLRGDWTLEPPFC 58
+ C+EG+ L G +CT G WT P C
Sbjct: 290 FSCEEGFALVGPEVVQCTASGVWTAPAPVC 319
Score = 32.3 bits (70), Expect = 9.7
Identities = 20/62 (32%), Positives = 27/62 (43%), Gaps = 3/62 (4%)
Query: 20 NIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTNVAFRKPANQSTTVRGGAA 79
N G+I + C EG L G+ Q C G W+ P C A ++ T GGA
Sbjct: 661 NFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTC---QAGPLTIQEALTYFGGAV 717
Query: 80 AN 81
A+
Sbjct: 718 AS 719
>AL022146-8|CAI22758.1| 753|Homo sapiens selectin P (granule
membrane protein 140kDa, antigen CD62) protein.
Length = 753
Score = 217 bits (529), Expect = 2e-55
Identities = 178/703 (25%), Positives = 282/703 (40%), Gaps = 91/703 (12%)
Query: 236 SFDEARKQCQSHGGDLIHGFQGATSSFLTQELERRKAQLKTQLVWIGAQKEPGLTSRTWQ 295
S++ +RK CQ+ DL+ +L + L + WIG +K ++TW
Sbjct: 37 SWNISRKYCQNRYTDLVAIQNKNEIDYLNKVLP-----YYSSYYWIGIRKN----NKTWT 87
Query: 296 WVDGELV---SKPSWGKDQPNNYNGEQNCV---VLDGGRGWLWNDVGCNLDYLHWICQYL 349
WV + +W ++PNN ++CV + WND C L H +C
Sbjct: 88 WVGTKKALTNEAENWADNEPNNKRNNEDCVEIYIKSPSAPGKWNDEHC-LKKKHALCY-- 144
Query: 350 PPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYV 409
T D ++ + G +C E +G+ + C GF+ P C+YV
Sbjct: 145 --TASCQD--MSCSKQG-----------ECLE---TIGNYTCSCYP-GFYG---PECEYV 182
Query: 410 N-CGGLTPIEDGDVALID--NRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRC 466
CG L + + + ++ + C + + + G + C GIW + P+C
Sbjct: 183 RECGELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQC 242
Query: 467 LFDWCPDPPAVSNASVT-VNGHKA---GSLASYTCENGHILSGSTSVTCTLGGAWSGVPP 522
L CP ++T ++ KA S S++CE G L G V CT G W+ P
Sbjct: 243 LAAQCPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASGVWTAPAP 302
Query: 523 SCKYVNCGT--PTIHKGSFVLINGTTT--YGSIAQFTCEPDYWLNGAEELVCNRDGKWSY 578
CK ++C +H GS Y + F C + L GA+ + C+ G+W+
Sbjct: 303 VCKAISCEPLESPVH-GSMDCSPSLRAFQYDTNCSFRCAEGFMLRGADIVRCDNLGQWTA 361
Query: 579 DIPSCELTSCPEPEVPSGGYME------AFDYYVHSTINFHCEAGHKLIGEPNLVCQQDG 632
P C+ C + VP+ + AF Y S +F C G L+G L C G
Sbjct: 362 PAPVCQALQCQDLPVPNEARVNCSHPFGAFRY--QSVCSFTCNEGLLLVGASVLQCLATG 419
Query: 633 EWSGDSPTCEYIDCGKLPTLPYGTMELLN--GTTHLGSVIQYSCTTNYRLVGPVRRTCTE 690
W+ P C+ I C L + GTM + G++ S Q+ C Y L GP R CT
Sbjct: 420 NWNSVPPECQAIPCTPLLSPQNGTMTCVQPLGSSSYKSTCQFICDEGYSLSGPERLDCTR 479
Query: 691 EFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVK 750
+W+DS P CE I+C + E+ + D D + +G+
Sbjct: 480 SGRWTDSPPMCEAIKCPELFAPEQG-----------------SLDCSDTRGEFNVGSTCH 522
Query: 751 YRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYV-DCGNPGRIENGKVTLPSNATFY---- 805
+ C+ G+K+ G + C +G+WS T PTC+ + PG ++ +T P T Y
Sbjct: 523 FSCDNGFKLEGPNNVECTTSGRWSATPPTCKGIASLPTPG-VQCPALTTPGQGTMYCRHH 581
Query: 806 ------GATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLL 859
T ++ C+ + L G C+ +G W+ P C+ + C +
Sbjct: 582 PGTFGFNTTCYFGCNAGFTLIGDSTLSCRPSGQWTAVTPACRAVKCSELHVNKPIAMNCS 641
Query: 860 VVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVC 902
+ S G + C G L G C G W+ TVP C
Sbjct: 642 NLWGNFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTC 684
Score = 208 bits (509), Expect = 6e-53
Identities = 128/430 (29%), Positives = 191/430 (44%), Gaps = 44/430 (10%)
Query: 377 YKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGL-TPIEDG-DVALIDNRTTHGAR 434
+ C EG L+G + C G W+ P CK ++C L +P+ D + +
Sbjct: 275 FSCEEGFALVGPEVVQCTASGVWTAPAPVCKAISCEPLESPVHGSMDCSPSLRAFQYDTN 334
Query: 435 ALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAG---- 490
+ C E F L G C + G W AP C C D P + A V + H G
Sbjct: 335 CSFRCAEGFMLRGADIVRCDNLGQWTAPAPVCQALQCQDLPVPNEARVNCS-HPFGAFRY 393
Query: 491 -SLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTI--HKGSFVLIN--GT 545
S+ S+TC G +L G++ + C G W+ VPP C+ + C TP + G+ + G+
Sbjct: 394 QSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPECQAIPC-TPLLSPQNGTMTCVQPLGS 452
Query: 546 TTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFD-- 603
++Y S QF C+ Y L+G E L C R G+W+ P CE CPE P G ++ D
Sbjct: 453 SSYKSTCQFICDEGYSLSGPERLDCTRSGRWTDSPPMCEAIKCPELFAPEQGSLDCSDTR 512
Query: 604 --YYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYI--------DCGKLPTLP 653
+ V ST +F C+ G KL G N+ C G WS PTC+ I C L T
Sbjct: 513 GEFNVGSTCHFSCDNGFKLEGPNNVECTTSGRWSATPPTCKGIASLPTPGVQCPALTTPG 572
Query: 654 YGTMELLN--GTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIV 711
GTM + GT + + C + L+G +C QW+ +P C ++CS+ +
Sbjct: 573 QGTMYCRHHPGTFGFNTTCYFGCNAGFTLIGDSTLSCRPSGQWTAVTPACRAVKCSE-LH 631
Query: 712 AEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNG 771
K I N + + G++ + C +G + G + + C++NG
Sbjct: 632 VNKPIAMNCSN----------------LWGNFSYGSICSFHCLEGQLLNGSAQTACQENG 675
Query: 772 QWSGTTPTCQ 781
WS T PTCQ
Sbjct: 676 HWSTTVPTCQ 685
Score = 191 bits (465), Expect = 1e-47
Identities = 127/508 (25%), Positives = 206/508 (40%), Gaps = 42/508 (8%)
Query: 479 NASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTI-HKG 537
N S + S S+ C +G+ ++G + + C G W+ PP C C I +G
Sbjct: 197 NCSHPLGNFSFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQCLAAQCPPLKIPERG 256
Query: 538 SFVLINGTTTYG--SIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPS 595
+ ++ + S F+CE + L G E + C G W+ P C+ SC E P
Sbjct: 257 NMTCLHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASGVWTAPAPVCKAISCEPLESPV 316
Query: 596 GGYME------AFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKL 649
G M+ AF Y + +F C G L G + C G+W+ +P C+ + C L
Sbjct: 317 HGSMDCSPSLRAFQY--DTNCSFRCAEGFMLRGADIVRCDNLGQWTAPAPVCQALQCQDL 374
Query: 650 PTLPYGTMELLN--GTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCS 707
P + + G SV ++C LVG C W+ P C+ I C+
Sbjct: 375 PVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPECQAIPCT 434
Query: 708 DPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTC 767
P+++ ++ T ++ + +T ++ C++GY + G C
Sbjct: 435 -PLLSPQNGTM----------TCVQPLGSSSYKST------CQFICDEGYSLSGPERLDC 477
Query: 768 EDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFY--GATAFYQCDENWELEGVIRR 825
+G+W+ + P C+ + C E G + + G+T + CD ++LEG
Sbjct: 478 TRSGRWTDSPPMCEAIKCPELFAPEQGSLDCSDTRGEFNVGSTCHFSCDNGFKLEGPNNV 537
Query: 826 MCQENGTWSLEPPICKEI-TCPDPSAQIKA----GSGLLVVT---STLSIGGEAHYQCER 877
C +G WS PP CK I + P P Q A G G + T ++ C
Sbjct: 538 ECTTSGRWSATPPTCKGIASLPTPGVQCPALTTPGQGTMYCRHHPGTFGFNTTCYFGCNA 597
Query: 878 GYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISN--GSTLFGSSVEYYC 935
G+ L G T +C GQW P C + C + + SN G+ +GS ++C
Sbjct: 598 GFTLIGDSTLSCRPSGQWTAVTPACRAVKCSELHVNKPIAMNCSNLWGNFSYGSICSFHC 657
Query: 936 LSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
L G C ++G WS P+C+
Sbjct: 658 LEGQLLNGSAQTACQENGHWSTTVPTCQ 685
Score = 188 bits (457), Expect = 1e-46
Identities = 123/489 (25%), Positives = 204/489 (41%), Gaps = 45/489 (9%)
Query: 498 ENGHILSGSTSVTCTLGGAWSGVPPSCKYVN-CGTPTIHKGSFVLIN-----GTTTYGSI 551
+ G L + TC+ + G P C+YV CG + VL+N G ++ S
Sbjct: 155 KQGECLETIGNYTCSCYPGFYG--PECEYVRECGE--LELPQHVLMNCSHPLGNFSFNSQ 210
Query: 552 AQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYM----EAFDYYVH 607
F C Y +NG +L C G W+ P C CP ++P G M A +
Sbjct: 211 CSFHCTDGYQVNGPSKLECLASGIWTNKPPQCLAAQCPPLKIPERGNMTCLHSAKAFQHQ 270
Query: 608 STINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTT--H 665
S+ +F CE G L+G + C G W+ +P C+ I C L + +G+M+
Sbjct: 271 SSCSFSCEEGFALVGPEVVQCTASGVWTAPAPVCKAISCEPLESPVHGSMDCSPSLRAFQ 330
Query: 666 LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRS 725
+ + C + L G C QW+ +P C+ ++C D V ++ V+ S
Sbjct: 331 YDTNCSFRCAEGFMLRGADIVRCDNLGQWTAPAPVCQALQCQDLPVPNEARVNC-----S 385
Query: 726 HGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDC 785
H +R ++ + C +G ++G S+ C G W+ P CQ + C
Sbjct: 386 HPF------------GAFRYQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPECQAIPC 433
Query: 786 GNPGRIENGKVTL--PSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEI 843
+NG +T P ++ Y +T + CDE + L G R C +G W+ PP+C+ I
Sbjct: 434 TPLLSPQNGTMTCVQPLGSSSYKSTCQFICDEGYSLSGPERLDCTRSGRWTDSPPMCEAI 493
Query: 844 TCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVC- 902
CP+ A + ++G H+ C+ G+ L+G C + G+W+ T P C
Sbjct: 494 KCPELFAPEQGSLDCSDTRGEFNVGSTCHFSCDNGFKLEGPNNVECTTSGRWSATPPTCK 553
Query: 903 ----IP---IDCRSPGNIENGKIVISNGSTLFGSSVEYY--CLSQYQRVGPFLRKCLDDG 953
+P + C + G + + FG + Y C + + +G C G
Sbjct: 554 GIASLPTPGVQCPALTTPGQGTMYCRHHPGTFGFNTTCYFGCNAGFTLIGDSTLSCRPSG 613
Query: 954 RWSGEEPSC 962
+W+ P+C
Sbjct: 614 QWTAVTPAC 622
Score = 109 bits (262), Expect = 5e-23
Identities = 74/259 (28%), Positives = 109/259 (42%), Gaps = 21/259 (8%)
Query: 346 CQYLPPT-CGSPDKLLNTTI--LGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGA 402
CQ +P T SP T + LG+ S + C EG+ L G + C + G W+ +
Sbjct: 428 CQAIPCTPLLSPQNGTMTCVQPLGSS-SYKSTCQFICDEGYSLSGPERLDCTRSGRWTDS 486
Query: 403 PPSCKYVNCGGLTPIEDGDVALIDNRTTH--GARALYSCRENFTLVGNPERTCGDEGIWD 460
PP C+ + C L E G + D R G+ +SC F L G C G W
Sbjct: 487 PPMCEAIKCPELFAPEQGSLDCSDTRGEFNVGSTCHFSCDNGFKLEGPNNVECTTSGRWS 546
Query: 461 GEAPRCLFDWCPDPPAVSNASVTVNG-------HKAGSLASYT-----CENGHILSGSTS 508
P C P V ++T G H G+ T C G L G ++
Sbjct: 547 ATPPTCKGIASLPTPGVQCPALTTPGQGTMYCRHHPGTFGFNTTCYFGCNAGFTLIGDST 606
Query: 509 VTCTLGGAWSGVPPSCKYVNCGTPTIHKGSFVLIN---GTTTYGSIAQFTCEPDYWLNGA 565
++C G W+ V P+C+ V C ++K + + G +YGSI F C LNG+
Sbjct: 607 LSCRPSGQWTAVTPACRAVKCSELHVNKPIAMNCSNLWGNFSYGSICSFHCLEGQLLNGS 666
Query: 566 EELVCNRDGKWSYDIPSCE 584
+ C +G WS +P+C+
Sbjct: 667 AQTACQENGHWSTTVPTCQ 685
Score = 97.5 bits (232), Expect = 2e-19
Identities = 59/240 (24%), Positives = 97/240 (40%), Gaps = 7/240 (2%)
Query: 728 HTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGN 787
H L+ S +GN + + + C GY+V G S C +G W+ P C C
Sbjct: 193 HVLMNCS--HPLGN-FSFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQCLAAQCPP 249
Query: 788 PGRIENGKVT-LPSNATF-YGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITC 845
E G +T L S F + ++ + C+E + L G C +G W+ P+CK I+C
Sbjct: 250 LKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASGVWTAPAPVCKAISC 309
Query: 846 PDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPI 905
+ + ++C G+ L+G C + GQW PVC +
Sbjct: 310 EPLESPVHGSMDCSPSLRAFQYDTNCSFRCAEGFMLRGADIVRCDNLGQWTAPAPVCQAL 369
Query: 906 DCRSPGNIENGKIVISN--GSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
C+ ++ S+ G+ + S + C VG + +CL G W+ P C+
Sbjct: 370 QCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPECQ 429
Score = 73.3 bits (172), Expect = 4e-12
Identities = 44/192 (22%), Positives = 76/192 (39%), Gaps = 7/192 (3%)
Query: 778 PTCQYV-DCGN---PGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTW 833
P C+YV +CG P + N +F +F+ C + +++ G + C +G W
Sbjct: 177 PECEYVRECGELELPQHVLMNCSHPLGNFSFNSQCSFH-CTDGYQVNGPSKLECLASGIW 235
Query: 834 SLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKG 893
+ +PP C CP + L + CE G+ L G + C + G
Sbjct: 236 TNKPPQCLAAQCPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASG 295
Query: 894 QWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLF--GSSVEYYCLSQYQRVGPFLRKCLD 951
W PVC I C + +G + S F ++ + C + G + +C +
Sbjct: 296 VWTAPAPVCKAISCEPLESPVHGSMDCSPSLRAFQYDTNCSFRCAEGFMLRGADIVRCDN 355
Query: 952 DGRWSGEEPSCE 963
G+W+ P C+
Sbjct: 356 LGQWTAPAPVCQ 367
Score = 54.8 bits (126), Expect = 2e-06
Identities = 27/109 (24%), Positives = 45/109 (41%), Gaps = 2/109 (1%)
Query: 866 SIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGST 925
S + + C GY + G C++ G W P C+ C E G + + +
Sbjct: 206 SFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQCLAAQCPPLKIPERGNMTCLHSAK 265
Query: 926 LFG--SSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCELATNEAVDS 972
F SS + C + VGP + +C G W+ P C+ + E ++S
Sbjct: 266 AFQHQSSCSFSCEEGFALVGPEVVQCTASGVWTAPAPVCKAISCEPLES 314
Score = 40.7 bits (91), Expect = 0.028
Identities = 15/28 (53%), Positives = 17/28 (60%)
Query: 31 CDEGYELFGARQRECTLRGDWTLEPPFC 58
CDEGY L G + +CT G WT PP C
Sbjct: 463 CDEGYSLSGPERLDCTRSGRWTDSPPMC 490
Score = 38.7 bits (86), Expect = 0.11
Identities = 14/35 (40%), Positives = 19/35 (54%)
Query: 24 GTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
G+ + CD G++L G ECT G W+ PP C
Sbjct: 518 GSTCHFSCDNGFKLEGPNNVECTTSGRWSATPPTC 552
Score = 35.9 bits (79), Expect = 0.79
Identities = 16/58 (27%), Positives = 28/58 (48%), Gaps = 1/58 (1%)
Query: 2 CGHPAVPPNARVSIPNE-ENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
CG +P + ++ + N + + C +GY++ G + EC G WT +PP C
Sbjct: 185 CGELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQC 242
Score = 34.7 bits (76), Expect = 1.8
Identities = 18/59 (30%), Positives = 27/59 (45%), Gaps = 1/59 (1%)
Query: 1 RCGHPAVPPNARVSIPNEENIVA-GTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
+C VP ARV+ + ++ + C+EG L GA +C G+W PP C
Sbjct: 370 QCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPEC 428
Score = 34.3 bits (75), Expect = 2.4
Identities = 12/30 (40%), Positives = 16/30 (53%)
Query: 29 YECDEGYELFGARQRECTLRGDWTLEPPFC 58
+ C+EG+ L G +CT G WT P C
Sbjct: 275 FSCEEGFALVGPEVVQCTASGVWTAPAPVC 304
Score = 32.3 bits (70), Expect = 9.7
Identities = 20/62 (32%), Positives = 27/62 (43%), Gaps = 3/62 (4%)
Query: 20 NIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTNVAFRKPANQSTTVRGGAA 79
N G+I + C EG L G+ Q C G W+ P C A ++ T GGA
Sbjct: 646 NFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTC---QAGPLTIQEALTYFGGAV 702
Query: 80 AN 81
A+
Sbjct: 703 AS 704
>AL022146-5|CAI22751.1| 768|Homo sapiens selectin P (granule
membrane protein 140kDa, antigen CD62) protein.
Length = 768
Score = 217 bits (529), Expect = 2e-55
Identities = 178/703 (25%), Positives = 282/703 (40%), Gaps = 91/703 (12%)
Query: 236 SFDEARKQCQSHGGDLIHGFQGATSSFLTQELERRKAQLKTQLVWIGAQKEPGLTSRTWQ 295
S++ +RK CQ+ DL+ +L + L + WIG +K ++TW
Sbjct: 52 SWNISRKYCQNRYTDLVAIQNKNEIDYLNKVLP-----YYSSYYWIGIRKN----NKTWT 102
Query: 296 WVDGELV---SKPSWGKDQPNNYNGEQNCV---VLDGGRGWLWNDVGCNLDYLHWICQYL 349
WV + +W ++PNN ++CV + WND C L H +C
Sbjct: 103 WVGTKKALTNEAENWADNEPNNKRNNEDCVEIYIKSPSAPGKWNDEHC-LKKKHALCY-- 159
Query: 350 PPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYV 409
T D ++ + G +C E +G+ + C GF+ P C+YV
Sbjct: 160 --TASCQD--MSCSKQG-----------ECLE---TIGNYTCSCYP-GFYG---PECEYV 197
Query: 410 N-CGGLTPIEDGDVALID--NRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRC 466
CG L + + + ++ + C + + + G + C GIW + P+C
Sbjct: 198 RECGELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQC 257
Query: 467 LFDWCPDPPAVSNASVT-VNGHKA---GSLASYTCENGHILSGSTSVTCTLGGAWSGVPP 522
L CP ++T ++ KA S S++CE G L G V CT G W+ P
Sbjct: 258 LAAQCPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASGVWTAPAP 317
Query: 523 SCKYVNCGT--PTIHKGSFVLINGTTT--YGSIAQFTCEPDYWLNGAEELVCNRDGKWSY 578
CK ++C +H GS Y + F C + L GA+ + C+ G+W+
Sbjct: 318 VCKAISCEPLESPVH-GSMDCSPSLRAFQYDTNCSFRCAEGFMLRGADIVRCDNLGQWTA 376
Query: 579 DIPSCELTSCPEPEVPSGGYME------AFDYYVHSTINFHCEAGHKLIGEPNLVCQQDG 632
P C+ C + VP+ + AF Y S +F C G L+G L C G
Sbjct: 377 PAPVCQALQCQDLPVPNEARVNCSHPFGAFRY--QSVCSFTCNEGLLLVGASVLQCLATG 434
Query: 633 EWSGDSPTCEYIDCGKLPTLPYGTMELLN--GTTHLGSVIQYSCTTNYRLVGPVRRTCTE 690
W+ P C+ I C L + GTM + G++ S Q+ C Y L GP R CT
Sbjct: 435 NWNSVPPECQAIPCTPLLSPQNGTMTCVQPLGSSSYKSTCQFICDEGYSLSGPERLDCTR 494
Query: 691 EFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVK 750
+W+DS P CE I+C + E+ + D D + +G+
Sbjct: 495 SGRWTDSPPMCEAIKCPELFAPEQG-----------------SLDCSDTRGEFNVGSTCH 537
Query: 751 YRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYV-DCGNPGRIENGKVTLPSNATFY---- 805
+ C+ G+K+ G + C +G+WS T PTC+ + PG ++ +T P T Y
Sbjct: 538 FSCDNGFKLEGPNNVECTTSGRWSATPPTCKGIASLPTPG-VQCPALTTPGQGTMYCRHH 596
Query: 806 ------GATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLL 859
T ++ C+ + L G C+ +G W+ P C+ + C +
Sbjct: 597 PGTFGFNTTCYFGCNAGFTLIGDSTLSCRPSGQWTAVTPACRAVKCSELHVNKPIAMNCS 656
Query: 860 VVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVC 902
+ S G + C G L G C G W+ TVP C
Sbjct: 657 NLWGNFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTC 699
Score = 208 bits (509), Expect = 6e-53
Identities = 128/430 (29%), Positives = 191/430 (44%), Gaps = 44/430 (10%)
Query: 377 YKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGL-TPIEDG-DVALIDNRTTHGAR 434
+ C EG L+G + C G W+ P CK ++C L +P+ D + +
Sbjct: 290 FSCEEGFALVGPEVVQCTASGVWTAPAPVCKAISCEPLESPVHGSMDCSPSLRAFQYDTN 349
Query: 435 ALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAG---- 490
+ C E F L G C + G W AP C C D P + A V + H G
Sbjct: 350 CSFRCAEGFMLRGADIVRCDNLGQWTAPAPVCQALQCQDLPVPNEARVNCS-HPFGAFRY 408
Query: 491 -SLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTI--HKGSFVLIN--GT 545
S+ S+TC G +L G++ + C G W+ VPP C+ + C TP + G+ + G+
Sbjct: 409 QSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPECQAIPC-TPLLSPQNGTMTCVQPLGS 467
Query: 546 TTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFD-- 603
++Y S QF C+ Y L+G E L C R G+W+ P CE CPE P G ++ D
Sbjct: 468 SSYKSTCQFICDEGYSLSGPERLDCTRSGRWTDSPPMCEAIKCPELFAPEQGSLDCSDTR 527
Query: 604 --YYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYI--------DCGKLPTLP 653
+ V ST +F C+ G KL G N+ C G WS PTC+ I C L T
Sbjct: 528 GEFNVGSTCHFSCDNGFKLEGPNNVECTTSGRWSATPPTCKGIASLPTPGVQCPALTTPG 587
Query: 654 YGTMELLN--GTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIV 711
GTM + GT + + C + L+G +C QW+ +P C ++CS+ +
Sbjct: 588 QGTMYCRHHPGTFGFNTTCYFGCNAGFTLIGDSTLSCRPSGQWTAVTPACRAVKCSE-LH 646
Query: 712 AEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNG 771
K I N + + G++ + C +G + G + + C++NG
Sbjct: 647 VNKPIAMNCSN----------------LWGNFSYGSICSFHCLEGQLLNGSAQTACQENG 690
Query: 772 QWSGTTPTCQ 781
WS T PTCQ
Sbjct: 691 HWSTTVPTCQ 700
Score = 191 bits (465), Expect = 1e-47
Identities = 127/508 (25%), Positives = 206/508 (40%), Gaps = 42/508 (8%)
Query: 479 NASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTI-HKG 537
N S + S S+ C +G+ ++G + + C G W+ PP C C I +G
Sbjct: 212 NCSHPLGNFSFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQCLAAQCPPLKIPERG 271
Query: 538 SFVLINGTTTYG--SIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPS 595
+ ++ + S F+CE + L G E + C G W+ P C+ SC E P
Sbjct: 272 NMTCLHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASGVWTAPAPVCKAISCEPLESPV 331
Query: 596 GGYME------AFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKL 649
G M+ AF Y + +F C G L G + C G+W+ +P C+ + C L
Sbjct: 332 HGSMDCSPSLRAFQY--DTNCSFRCAEGFMLRGADIVRCDNLGQWTAPAPVCQALQCQDL 389
Query: 650 PTLPYGTMELLN--GTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCS 707
P + + G SV ++C LVG C W+ P C+ I C+
Sbjct: 390 PVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPECQAIPCT 449
Query: 708 DPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTC 767
P+++ ++ T ++ + +T ++ C++GY + G C
Sbjct: 450 -PLLSPQNGTM----------TCVQPLGSSSYKST------CQFICDEGYSLSGPERLDC 492
Query: 768 EDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFY--GATAFYQCDENWELEGVIRR 825
+G+W+ + P C+ + C E G + + G+T + CD ++LEG
Sbjct: 493 TRSGRWTDSPPMCEAIKCPELFAPEQGSLDCSDTRGEFNVGSTCHFSCDNGFKLEGPNNV 552
Query: 826 MCQENGTWSLEPPICKEI-TCPDPSAQIKA----GSGLLVVT---STLSIGGEAHYQCER 877
C +G WS PP CK I + P P Q A G G + T ++ C
Sbjct: 553 ECTTSGRWSATPPTCKGIASLPTPGVQCPALTTPGQGTMYCRHHPGTFGFNTTCYFGCNA 612
Query: 878 GYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISN--GSTLFGSSVEYYC 935
G+ L G T +C GQW P C + C + + SN G+ +GS ++C
Sbjct: 613 GFTLIGDSTLSCRPSGQWTAVTPACRAVKCSELHVNKPIAMNCSNLWGNFSYGSICSFHC 672
Query: 936 LSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
L G C ++G WS P+C+
Sbjct: 673 LEGQLLNGSAQTACQENGHWSTTVPTCQ 700
Score = 188 bits (457), Expect = 1e-46
Identities = 123/489 (25%), Positives = 204/489 (41%), Gaps = 45/489 (9%)
Query: 498 ENGHILSGSTSVTCTLGGAWSGVPPSCKYVN-CGTPTIHKGSFVLIN-----GTTTYGSI 551
+ G L + TC+ + G P C+YV CG + VL+N G ++ S
Sbjct: 170 KQGECLETIGNYTCSCYPGFYG--PECEYVRECGE--LELPQHVLMNCSHPLGNFSFNSQ 225
Query: 552 AQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYM----EAFDYYVH 607
F C Y +NG +L C G W+ P C CP ++P G M A +
Sbjct: 226 CSFHCTDGYQVNGPSKLECLASGIWTNKPPQCLAAQCPPLKIPERGNMTCLHSAKAFQHQ 285
Query: 608 STINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTT--H 665
S+ +F CE G L+G + C G W+ +P C+ I C L + +G+M+
Sbjct: 286 SSCSFSCEEGFALVGPEVVQCTASGVWTAPAPVCKAISCEPLESPVHGSMDCSPSLRAFQ 345
Query: 666 LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRS 725
+ + C + L G C QW+ +P C+ ++C D V ++ V+ S
Sbjct: 346 YDTNCSFRCAEGFMLRGADIVRCDNLGQWTAPAPVCQALQCQDLPVPNEARVNC-----S 400
Query: 726 HGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDC 785
H +R ++ + C +G ++G S+ C G W+ P CQ + C
Sbjct: 401 HPF------------GAFRYQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPECQAIPC 448
Query: 786 GNPGRIENGKVTL--PSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEI 843
+NG +T P ++ Y +T + CDE + L G R C +G W+ PP+C+ I
Sbjct: 449 TPLLSPQNGTMTCVQPLGSSSYKSTCQFICDEGYSLSGPERLDCTRSGRWTDSPPMCEAI 508
Query: 844 TCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVC- 902
CP+ A + ++G H+ C+ G+ L+G C + G+W+ T P C
Sbjct: 509 KCPELFAPEQGSLDCSDTRGEFNVGSTCHFSCDNGFKLEGPNNVECTTSGRWSATPPTCK 568
Query: 903 ----IP---IDCRSPGNIENGKIVISNGSTLFGSSVEYY--CLSQYQRVGPFLRKCLDDG 953
+P + C + G + + FG + Y C + + +G C G
Sbjct: 569 GIASLPTPGVQCPALTTPGQGTMYCRHHPGTFGFNTTCYFGCNAGFTLIGDSTLSCRPSG 628
Query: 954 RWSGEEPSC 962
+W+ P+C
Sbjct: 629 QWTAVTPAC 637
Score = 109 bits (262), Expect = 5e-23
Identities = 74/259 (28%), Positives = 109/259 (42%), Gaps = 21/259 (8%)
Query: 346 CQYLPPT-CGSPDKLLNTTI--LGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGA 402
CQ +P T SP T + LG+ S + C EG+ L G + C + G W+ +
Sbjct: 443 CQAIPCTPLLSPQNGTMTCVQPLGSS-SYKSTCQFICDEGYSLSGPERLDCTRSGRWTDS 501
Query: 403 PPSCKYVNCGGLTPIEDGDVALIDNRTTH--GARALYSCRENFTLVGNPERTCGDEGIWD 460
PP C+ + C L E G + D R G+ +SC F L G C G W
Sbjct: 502 PPMCEAIKCPELFAPEQGSLDCSDTRGEFNVGSTCHFSCDNGFKLEGPNNVECTTSGRWS 561
Query: 461 GEAPRCLFDWCPDPPAVSNASVTVNG-------HKAGSLASYT-----CENGHILSGSTS 508
P C P V ++T G H G+ T C G L G ++
Sbjct: 562 ATPPTCKGIASLPTPGVQCPALTTPGQGTMYCRHHPGTFGFNTTCYFGCNAGFTLIGDST 621
Query: 509 VTCTLGGAWSGVPPSCKYVNCGTPTIHKGSFVLIN---GTTTYGSIAQFTCEPDYWLNGA 565
++C G W+ V P+C+ V C ++K + + G +YGSI F C LNG+
Sbjct: 622 LSCRPSGQWTAVTPACRAVKCSELHVNKPIAMNCSNLWGNFSYGSICSFHCLEGQLLNGS 681
Query: 566 EELVCNRDGKWSYDIPSCE 584
+ C +G WS +P+C+
Sbjct: 682 AQTACQENGHWSTTVPTCQ 700
Score = 97.5 bits (232), Expect = 2e-19
Identities = 59/240 (24%), Positives = 97/240 (40%), Gaps = 7/240 (2%)
Query: 728 HTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGN 787
H L+ S +GN + + + C GY+V G S C +G W+ P C C
Sbjct: 208 HVLMNCS--HPLGN-FSFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQCLAAQCPP 264
Query: 788 PGRIENGKVT-LPSNATF-YGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITC 845
E G +T L S F + ++ + C+E + L G C +G W+ P+CK I+C
Sbjct: 265 LKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASGVWTAPAPVCKAISC 324
Query: 846 PDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPI 905
+ + ++C G+ L+G C + GQW PVC +
Sbjct: 325 EPLESPVHGSMDCSPSLRAFQYDTNCSFRCAEGFMLRGADIVRCDNLGQWTAPAPVCQAL 384
Query: 906 DCRSPGNIENGKIVISN--GSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
C+ ++ S+ G+ + S + C VG + +CL G W+ P C+
Sbjct: 385 QCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPECQ 444
Score = 73.3 bits (172), Expect = 4e-12
Identities = 44/192 (22%), Positives = 76/192 (39%), Gaps = 7/192 (3%)
Query: 778 PTCQYV-DCGN---PGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTW 833
P C+YV +CG P + N +F +F+ C + +++ G + C +G W
Sbjct: 192 PECEYVRECGELELPQHVLMNCSHPLGNFSFNSQCSFH-CTDGYQVNGPSKLECLASGIW 250
Query: 834 SLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKG 893
+ +PP C CP + L + CE G+ L G + C + G
Sbjct: 251 TNKPPQCLAAQCPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASG 310
Query: 894 QWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLF--GSSVEYYCLSQYQRVGPFLRKCLD 951
W PVC I C + +G + S F ++ + C + G + +C +
Sbjct: 311 VWTAPAPVCKAISCEPLESPVHGSMDCSPSLRAFQYDTNCSFRCAEGFMLRGADIVRCDN 370
Query: 952 DGRWSGEEPSCE 963
G+W+ P C+
Sbjct: 371 LGQWTAPAPVCQ 382
Score = 54.8 bits (126), Expect = 2e-06
Identities = 27/109 (24%), Positives = 45/109 (41%), Gaps = 2/109 (1%)
Query: 866 SIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGST 925
S + + C GY + G C++ G W P C+ C E G + + +
Sbjct: 221 SFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQCLAAQCPPLKIPERGNMTCLHSAK 280
Query: 926 LFG--SSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCELATNEAVDS 972
F SS + C + VGP + +C G W+ P C+ + E ++S
Sbjct: 281 AFQHQSSCSFSCEEGFALVGPEVVQCTASGVWTAPAPVCKAISCEPLES 329
Score = 40.7 bits (91), Expect = 0.028
Identities = 15/28 (53%), Positives = 17/28 (60%)
Query: 31 CDEGYELFGARQRECTLRGDWTLEPPFC 58
CDEGY L G + +CT G WT PP C
Sbjct: 478 CDEGYSLSGPERLDCTRSGRWTDSPPMC 505
Score = 38.7 bits (86), Expect = 0.11
Identities = 14/35 (40%), Positives = 19/35 (54%)
Query: 24 GTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
G+ + CD G++L G ECT G W+ PP C
Sbjct: 533 GSTCHFSCDNGFKLEGPNNVECTTSGRWSATPPTC 567
Score = 35.9 bits (79), Expect = 0.79
Identities = 16/58 (27%), Positives = 28/58 (48%), Gaps = 1/58 (1%)
Query: 2 CGHPAVPPNARVSIPNE-ENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
CG +P + ++ + N + + C +GY++ G + EC G WT +PP C
Sbjct: 200 CGELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQC 257
Score = 34.7 bits (76), Expect = 1.8
Identities = 18/59 (30%), Positives = 27/59 (45%), Gaps = 1/59 (1%)
Query: 1 RCGHPAVPPNARVSIPNEENIVA-GTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
+C VP ARV+ + ++ + C+EG L GA +C G+W PP C
Sbjct: 385 QCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPEC 443
Score = 34.3 bits (75), Expect = 2.4
Identities = 12/30 (40%), Positives = 16/30 (53%)
Query: 29 YECDEGYELFGARQRECTLRGDWTLEPPFC 58
+ C+EG+ L G +CT G WT P C
Sbjct: 290 FSCEEGFALVGPEVVQCTASGVWTAPAPVC 319
Score = 32.3 bits (70), Expect = 9.7
Identities = 20/62 (32%), Positives = 27/62 (43%), Gaps = 3/62 (4%)
Query: 20 NIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTNVAFRKPANQSTTVRGGAA 79
N G+I + C EG L G+ Q C G W+ P C A ++ T GGA
Sbjct: 661 NFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTC---QAGPLTIQEALTYFGGAV 717
Query: 80 AN 81
A+
Sbjct: 718 AS 719
>J03565-1|AAA35784.1| 1087|Homo sapiens CR2 protein.
Length = 1087
Score = 213 bits (521), Expect = 2e-54
Identities = 188/665 (28%), Positives = 274/665 (41%), Gaps = 81/665 (12%)
Query: 352 TCGSPDKLLNTTI--LGNDYDVGSRIVYKCPEGHMLLGDKSRHC----KKDGFWSGAPPS 405
+CGSP +LN I VG+ I Y C L+G+KS C K DG W P
Sbjct: 22 SCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPK 81
Query: 406 CKYVN--CGGLTPIEDGDVALIDNRT-THGARALYSCRENFTLVGNPERTCGDEGIWDG- 461
C+Y N PI G + + HG ++C+ NF++ GN C +W
Sbjct: 82 CEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWGPT 141
Query: 462 EAPRCLFDW---CPDPPAVSNA---SVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGG 515
P C+ + CP P + N S V G +Y+CE+G++L G + C G
Sbjct: 142 RLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSG 201
Query: 516 AWSGVPPSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGK 575
WS VPP+C+ C + V G A F C+ Y L G C G+
Sbjct: 202 KWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQ 261
Query: 576 ---WSYDIPSCELTSCPE-PEVPSGGYM--EAFDYYVHSTINFHCEAGHK------LIGE 623
W+ +P CE CP P + +G ++ + S + + C+ + LIGE
Sbjct: 262 GVAWT-KMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGE 320
Query: 624 PNLVC----QQDGEWSGDSPTCEY----IDCGKLPTLPYGTM--ELLNGTTHLGSVIQYS 673
L C Q+ G WSG +P CE + C P + G M + T+ +VI ++
Sbjct: 321 STLRCTVDSQKTGTWSGPAPRCELSTSAVQCPH-PQILRGRMVSGQKDRYTYNDTVI-FA 378
Query: 674 CTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRT 733
C + L G + C + W S+P CE+ C P +I++ DR ++R
Sbjct: 379 CMFGFTLKGSKQIRCNAQGTWEPSAPVCEK-ECQAP----PNILNGQKEDRH----MVR- 428
Query: 734 SDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIEN 793
+ G +KY C GY ++GE C G W+ P C+ C GR
Sbjct: 429 ---------FDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGR--- 476
Query: 794 GKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIK 853
+T P + F C E ++L G + + CQ W +E +CKEITCP P I
Sbjct: 477 QLLTKPQH-QFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPV-IY 534
Query: 854 AGSGLLVVTSTLSIGGEAHYQC----ERG--YNLKGHQTRTCIS----KGQWNGTVPVC- 902
G+ G Y C ERG ++L G T C S +G W+G P+C
Sbjct: 535 NGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCK 594
Query: 903 ---IPIDCRSPGNIENG-KIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGE 958
+ + C S +I NG KI + +V + C S + G +C D W E
Sbjct: 595 LSLLAVQC-SHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKRDNTWDPE 653
Query: 959 EPSCE 963
P CE
Sbjct: 654 IPVCE 658
Score = 206 bits (504), Expect = 3e-52
Identities = 174/636 (27%), Positives = 258/636 (40%), Gaps = 79/636 (12%)
Query: 372 GSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRTTH 431
G + Y C G++L+G+K +C G WS PP+C+ C L +G V
Sbjct: 176 GLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRV- 234
Query: 432 GARALYSCRENFTLVGNPERTC--GDEGIWDGEAPRCLFDWCPDPPAVSNASVTVN---G 486
G A + C E + L G P C +G+ + P C +CP PP + N N
Sbjct: 235 GVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTKMPVCEEIFCPSPPPILNGRHIGNSLAN 294
Query: 487 HKAGSLASYTC----ENG--HILSGSTSVTCTLG----GAWSGVPPSCKY----VNCGTP 532
GS+ +YTC E G IL G +++ CT+ G WSG P C+ V C P
Sbjct: 295 VSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHP 354
Query: 533 TIHKGSFVL-INGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEP 591
I +G V TY F C + L G++++ CN G W P CE P
Sbjct: 355 QILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKECQAPP 414
Query: 592 EVPSG----GYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCG 647
+ +G +M FD ++I + C G+ L+GE ++ C +G W+ P C+ C
Sbjct: 415 NILNGQKEDRHMVRFD--PGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACE 472
Query: 648 KLPTLPYGTMELLNGTTH--LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIR 705
+LL H + + SC Y+L G V + C W C+EI
Sbjct: 473 AT------GRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEIT 526
Query: 706 CSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKG------YKV 759
C P V N G +L + G V Y C G + +
Sbjct: 527 CPPP--------PVIYNGAHTGSSL----------EDFPYGTTVTYTCNPGPERGVEFSL 568
Query: 760 IGESLSTCEDN----GQWSGTTPTCQY----VDCGNPGRIENG-KVTLPSNATFYGATAF 810
IGES C N G WSG P C+ V C + I NG K++ FY T
Sbjct: 569 IGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHV-HIANGYKISGKEAPYFYNDTVT 627
Query: 811 YQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGE 870
++C + L+G + C+ + TW E P+C++ P P +G T G
Sbjct: 628 FKCYSGFTLKGSSQIRCKRDNTWDPEIPVCEKGCQPPPGLHHGRHTG--GNTVFFVSGMT 685
Query: 871 AHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSS 930
Y C+ GY L G+++ C+ G W+ + P C C+ ++ + GS +
Sbjct: 686 VDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRC-EETCQ---HVRQSLQELPAGSRV--EL 739
Query: 931 VEYYCLSQYQRVGPFLRKCLD--DGRWSGEEPSCEL 964
V C YQ G + C D +G W + P C++
Sbjct: 740 VNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKV 775
Score = 198 bits (483), Expect = 9e-50
Identities = 175/648 (27%), Positives = 250/648 (38%), Gaps = 73/648 (11%)
Query: 353 CGSPDKLLNTTILGND--YDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVN 410
C P L + G Y +++ C G L G K C G W + P C+
Sbjct: 351 CPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEK-E 409
Query: 411 CGGLTPIEDG---DVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL 467
C I +G D ++ R G YSC + LVG C EG+W P+C
Sbjct: 410 CQAPPNILNGQKEDRHMV--RFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCK 467
Query: 468 FDWCPDPPAVSNASVTVNGHK-AGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKY 526
C A +T H+ + +C G+ LSGS C W CK
Sbjct: 468 VAACE---ATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKE 524
Query: 527 VNCGTP-TIHKGSFVLIN-GTTTYGSIAQFTCEP------DYWLNGAEELVCNRD----G 574
+ C P I+ G+ + YG+ +TC P ++ L G + C + G
Sbjct: 525 ITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERG 584
Query: 575 KWSYDIPSCELT----SCPEPEVPSGGYMEAFD--YYVHSTINFHCEAGHKLIGEPNLVC 628
WS P C+L+ C + +G + + Y+ + T+ F C +G L G + C
Sbjct: 585 TWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRC 644
Query: 629 QQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHL-GSVIQYSCTTNYRLVGPVRRT 687
++D W + P CE C P L +G N + G + Y+C Y LVG
Sbjct: 645 KRDNTWDPEIPVCEK-GCQPPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIH 703
Query: 688 CTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGA 747
C WS S+PRCEE C +S+ + R L+ TS
Sbjct: 704 CMPSGNWSPSAPRCEET-CQH---VRQSLQELPAGSRVE---LVNTS------------- 743
Query: 748 LVKYRCEKGYKVIGESLSTCED--NGQWSGTTPTCQYVDCGNPGRIENGKVT-LPSNATF 804
C+ GY++ G + C+D NG W P C+ + C P I NGK T + +
Sbjct: 744 -----CQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFL 798
Query: 805 YGATAFYQCDENWELEGVIRRMCQEN---GTWSLEP--PICKEITCPDPSAQIKAGSGLL 859
YG Y+CD+ + L G + C W LE P C CP+P ++K G L
Sbjct: 799 YGNEVSYECDQGFYLLG--EKNCSAEVILKAWILERAFPQCLRSLCPNP--EVKHGYKLN 854
Query: 860 VVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIP---IDCRSPGNIENG 916
S S + C G+ + G + C + W VP CI I C P NG
Sbjct: 855 KTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNG 914
Query: 917 KIVISNGSTLF-GSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
N + G S+ Y C Y VG L C +G WS P C+
Sbjct: 915 NHTGGNIARFSPGMSILYSCDQGYLVVGEPLLLCTHEGTWSQPAPHCK 962
Score = 181 bits (441), Expect = 1e-44
Identities = 160/621 (25%), Positives = 246/621 (39%), Gaps = 66/621 (10%)
Query: 369 YDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNR 428
+D G+ I Y C G++L+G++S C +G W+ P CK C E L+
Sbjct: 429 FDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAAC------EATGRQLLTKP 482
Query: 429 TTHGAR--ALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVT--- 483
R SC E + L G+ + C W E C CP PP + N + T
Sbjct: 483 QHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSS 542
Query: 484 VNGHKAGSLASYTCENG------HILSGSTSVTCTLG----GAWSGVPPSCKY----VNC 529
+ G+ +YTC G L G +++ CT G WSG P CK V C
Sbjct: 543 LEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQC 602
Query: 530 GTPTIHKGSFVLINGTTT---YGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELT 586
+H + I+G Y F C + L G+ ++ C RD W +IP CE
Sbjct: 603 SH--VHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKRDNTWDPEIPVCEKG 660
Query: 587 SCPEPEVPSGGYMEAFDYYVHS--TINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYI 644
P P + G + + S T+++ C+ G+ L+G ++ C G WS +P CE
Sbjct: 661 CQPPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRCEET 720
Query: 645 DCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTC--TEEFQWSDSSPRCE 702
C + EL G+ ++ SC Y+L G + C E W P C+
Sbjct: 721 -CQHVRQ---SLQELPAGSRV--ELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCK 774
Query: 703 EIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGE 762
I C P V V G HT + ++N GN V Y C++G+ ++GE
Sbjct: 775 VIHCHPPPVI------VNGK-----HTGMM-AENFLYGNE------VSYECDQGFYLLGE 816
Query: 763 SLSTCEDNGQ-W--SGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWEL 819
+ E + W P C C NP K+ +A + + C+ + +
Sbjct: 817 KNCSAEVILKAWILERAFPQCLRSLCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIM 876
Query: 820 EGVIRRMCQENGTWSLEPPICKE---ITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCE 876
G C + TW P C + I CP P + G+ + S G Y C+
Sbjct: 877 NGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPP-KTPNGNHTGGNIARFSPGMSILYSCD 935
Query: 877 RGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIEN-GKIVISNGSTLFGSSVEYYC 935
+GY + G C +G W+ P C ++C SP +++ K + +G+ V C
Sbjct: 936 QGYLVVGEPLLLCTHEGTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLEC 995
Query: 936 LSQYQRVGPFLRKCLDDGRWS 956
Y G +C D +W+
Sbjct: 996 EDGYMLEGSPQSQCQSDHQWN 1016
Score = 178 bits (433), Expect = 1e-43
Identities = 159/612 (25%), Positives = 239/612 (39%), Gaps = 81/612 (13%)
Query: 404 PSCKYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTC----GDEGIW 459
P ++CG PI +G ++ G YSC F L+G C +G W
Sbjct: 16 PGVLGISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTW 75
Query: 460 DGEAPRC----LFDWCPDPPAVSNASVT-VNGHKAGSLASYTCENGHILSGSTSVTCTLG 514
D AP+C + CP+P + ++ G ++ C+ ++G+ SV C
Sbjct: 76 DKPAPKCEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQAN 135
Query: 515 GAWSGVP-PSCKYV---NC-GTPTIHKGSFVLIN-GTTTYGSIAQFTCEPDYWLNGAEEL 568
W P+C V C P IH G N G+ G ++CE Y L G + +
Sbjct: 136 NMWGPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKII 195
Query: 569 VCNRDGKWSYDIPSCELTSCPE-PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLV 627
C GKWS P+CE C P+G E V T NF C+ G++L G P+
Sbjct: 196 NCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSR 255
Query: 628 CQQDGE---WSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHL--GSVIQYSCT------T 676
C G+ W+ P CE I C P + G + N ++ GS++ Y+C
Sbjct: 256 CVIAGQGVAWT-KMPVCEEIFCPSPPPILNG-RHIGNSLANVSYGSIVTYTCDPDPEEGV 313
Query: 677 NYRLVGPVRRTCTEEFQ----WSDSSPRCE----EIRCSDPIVAEKSIVSVTGNDRSHGH 728
N+ L+G CT + Q WS +PRCE ++C P + +VS + ++
Sbjct: 314 NFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYTYND 373
Query: 729 TLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNP 788
T+I + C G+ + G C G W + P C+ +C P
Sbjct: 374 TVI-------------------FACMFGFTLKGSKQIRCNAQGTWEPSAPVCE-KECQAP 413
Query: 789 GRIENGKVTLPSNATFYGATAF-YQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPD 847
I NG+ F T+ Y C+ + L G C G W+ P CK C
Sbjct: 414 PNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACE- 472
Query: 848 PSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDC 907
G LL + + + C GY L G + C W + +C I C
Sbjct: 473 -----ATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITC 527
Query: 908 RSPGNIENGKIVISNGSTL----FGSSVEYYCLS------QYQRVGPFLRKCLDD----G 953
P I NG GS+L +G++V Y C ++ +G +C + G
Sbjct: 528 PPPPVIYNG---AHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERG 584
Query: 954 RWSGEEPSCELA 965
WSG P C+L+
Sbjct: 585 TWSGPAPLCKLS 596
Score = 167 bits (406), Expect = 2e-40
Identities = 138/483 (28%), Positives = 203/483 (42%), Gaps = 56/483 (11%)
Query: 520 VPPSCKYVNCGTPT-IHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVC----NRDG 574
V P ++CG+P I G + G++ +++C + L G + L+C DG
Sbjct: 14 VAPGVLGISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDG 73
Query: 575 KWSYDIPSCEL----TSCPEPEVPSGGYMEAFDYYVHS-TINFHCEAGHKLIGEPNLVCQ 629
W P CE +SCPEP VP G + Y H ++ F C+ + G ++ CQ
Sbjct: 74 TWDKPAPKCEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQ 133
Query: 630 QDGEWSGDS-PTCEYI---DCGKLPTLPYGTMELLN-GTTHLGSVIQYSCTTNYRLVGPV 684
+ W PTC + +C LP + G N G+ G + YSC + Y LVG
Sbjct: 134 ANNMWGPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEK 193
Query: 685 RRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYR 744
C +WS P CEE RC KS+ L R
Sbjct: 194 IINCLSSGKWSAVPPTCEEARC-------KSLGRFPNGKVKEPPIL-------------R 233
Query: 745 IGALVKYRCEKGYKVIGESLSTCEDNGQWSGTT--PTCQYVDCGNPGRIENGKVTLPSNA 802
+G + C++GY++ G S C GQ T P C+ + C +P I NG+ S A
Sbjct: 234 VGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTKMPVCEEIFCPSPPPILNGRHIGNSLA 293
Query: 803 TF-YGATAFYQCDE------NWELEGVIRRMC----QENGTWSLEPPICK----EITCPD 847
YG+ Y CD N+ L G C Q+ GTWS P C+ + CP
Sbjct: 294 NVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPH 353
Query: 848 PSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDC 907
P QI G + + + C G+ LKG + C ++G W + PVC +C
Sbjct: 354 P--QILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEK-EC 410
Query: 908 RSPGNIENGKIVISNGSTLF-GSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCELAT 966
++P NI NG+ + G+S++Y C Y VG +C +G W+ P C++A
Sbjct: 411 QAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAA 470
Query: 967 NEA 969
EA
Sbjct: 471 CEA 473
Score = 167 bits (405), Expect = 2e-40
Identities = 150/565 (26%), Positives = 218/565 (38%), Gaps = 78/565 (13%)
Query: 379 CPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDG-DVALIDNRTTHGARALY 437
C EG+ L G + C+ W CK + C I +G +G Y
Sbjct: 495 CGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTY 554
Query: 438 SCREN------FTLVGNPERTCG----DEGIWDGEAPRCLFDWCPDPPAVSNASVTV-NG 486
+C F+L+G C + G W G AP C AV + V + NG
Sbjct: 555 TCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLL----AVQCSHVHIANG 610
Query: 487 HK-AGSLASY--------TCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTIHKG 537
+K +G A Y C +G L GS+ + C W P C+ P +H G
Sbjct: 611 YKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKRDNTWDPEIPVCEKGCQPPPGLHHG 670
Query: 538 SFVLINGTTTY---GSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPE---- 590
G T + G +TC+P Y L G + + C G WS P CE T C
Sbjct: 671 RHT--GGNTVFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRCEET-CQHVRQS 727
Query: 591 -PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQ--QDGEWSGDSPTCEYIDCG 647
E+P+G +E +N C+ G++L G +CQ ++G W P C+ I C
Sbjct: 728 LQELPAGSRVEL--------VNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCH 779
Query: 648 KLPTLPYGTMELLNGTTHL-GSVIQYSCTTNYRLVGPVRRTCTEEF---QW--SDSSPRC 701
P + G + L G+ + Y C + L+G + C+ E W + P+C
Sbjct: 780 PPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLG--EKNCSAEVILKAWILERAFPQC 837
Query: 702 EEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIG 761
C +P V HG+ L +T + Y +V C G+ + G
Sbjct: 838 LRSLCPNPEV-------------KHGYKLNKTH------SAYSHNDIVYVDCNPGFIMNG 878
Query: 762 ESLSTCEDNGQWSGTTPTC---QYVDCGNPGRIENGKVTLPSNATFY-GATAFYQCDENW 817
+ C + W PTC ++ C P + NG T + A F G + Y CD+ +
Sbjct: 879 SRVIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGY 938
Query: 818 ELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCER 877
+ G +C GTWS P CKE+ C P+ GL G +CE
Sbjct: 939 LVVGEPLLLCTHEGTWSQPAPHCKEVNCSSPADMDGIQKGL-EPRKMYQYGAVVTLECED 997
Query: 878 GYNLKGHQTRTCISKGQWNGTVPVC 902
GY L+G C S QWN + VC
Sbjct: 998 GYMLEGSPQSQCQSDHQWNPPLAVC 1022
Score = 149 bits (362), Expect = 4e-35
Identities = 132/549 (24%), Positives = 217/549 (39%), Gaps = 58/549 (10%)
Query: 352 TCGSPDKLLNTTILGN---DYDVGSRIVYKCPEG------HMLLGDKSRHCKKD----GF 398
TC P + N G+ D+ G+ + Y C G L+G+ + C + G
Sbjct: 526 TCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGT 585
Query: 399 WSGAPPSCKY----VNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCG 454
WSG P CK V C + ++ + + + C FTL G+ + C
Sbjct: 586 WSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCK 645
Query: 455 DEGIWDGEAPRCLFDWCPDPPAVSNASVTVNG---HKAGSLASYTCENGHILSGSTSVTC 511
+ WD E P C C PP + + T +G YTC+ G++L G+ S+ C
Sbjct: 646 RDNTWDPEIPVCE-KGCQPPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIHC 704
Query: 512 TLGGAWSGVPPSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCN 571
G WS P C+ C + + L G+ + +C+ Y L G +C
Sbjct: 705 MPSGNWSPSAPRCEET-C--QHVRQSLQELPAGSRV--ELVNTSCQDGYQLTGHAYQMCQ 759
Query: 572 --RDGKWSYDIPSCELTSC-PEPEVPSGGY--MEAFDYYVHSTINFHCEAGHKLIGEPNL 626
+G W IP C++ C P P + +G + M A ++ + +++ C+ G L+GE N
Sbjct: 760 DAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKNC 819
Query: 627 VCQQDGE-WSGDS--PTCEYIDCGKLPTLPYG-TMELLNGTTHLGSVIQYSCTTNYRLVG 682
+ + W + P C C P + +G + + ++ C + + G
Sbjct: 820 SAEVILKAWILERAFPQCLRSLCPN-PEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNG 878
Query: 683 PVRRTCTEEFQWSDSSPRCEE---IRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDV 739
C + W P C + I C P T N G + R S
Sbjct: 879 SRVIRCHTDNTWVPGVPTCIKKAFIGCPPP--------PKTPNGNHTGGNIARFSP---- 926
Query: 740 GNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTL- 798
G + Y C++GY V+GE L C G WS P C+ V+C +P ++ + L
Sbjct: 927 ------GMSILYSCDQGYLVVGEPLLLCTHEGTWSQPAPHCKEVNCSSPADMDGIQKGLE 980
Query: 799 PSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGL 858
P YGA +C++ + LEG + CQ + W+ +C+ + I AG L
Sbjct: 981 PRKMYQYGAVVTLECEDGYMLEGSPQSQCQSDHQWNPPLAVCRSRSLAPVLCGIAAGLIL 1040
Query: 859 LVVTSTLSI 867
L +++
Sbjct: 1041 LTFLIVITL 1049
Score = 38.7 bits (86), Expect = 0.11
Identities = 19/56 (33%), Positives = 25/56 (44%), Gaps = 2/56 (3%)
Query: 5 PAVPP--NARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
PA+P N + N +I G Y C+ GY L G + C G W+ PP C
Sbjct: 155 PALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTC 210
Score = 38.7 bits (86), Expect = 0.11
Identities = 22/75 (29%), Positives = 29/75 (38%), Gaps = 1/75 (1%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTN 61
C P PN + N G +Y CD+GY + G CT G W+ P C
Sbjct: 905 CPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLVVGEPLLLCTHEGTWSQPAPHC-KE 963
Query: 62 VAFRKPANQSTTVRG 76
V PA+ +G
Sbjct: 964 VNCSSPADMDGIQKG 978
Score = 36.3 bits (80), Expect = 0.60
Identities = 19/54 (35%), Positives = 24/54 (44%), Gaps = 3/54 (5%)
Query: 8 PPNARVSIPNEENIVA---GTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
PPN + ++V GT Y C+ GY L G +CT G WT P C
Sbjct: 413 PPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQC 466
Score = 34.7 bits (76), Expect = 1.8
Identities = 16/58 (27%), Positives = 26/58 (44%), Gaps = 1/58 (1%)
Query: 1 RCGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
+C HP + VS + T+ ++ C G+ L G++Q C +G W P C
Sbjct: 350 QCPHPQILRGRMVSGQKDRYTYNDTV-IFACMFGFTLKGSKQIRCNAQGTWEPSAPVC 406
Score = 34.3 bits (75), Expect = 2.4
Identities = 18/57 (31%), Positives = 24/57 (42%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C P + R + N V+G Y CD GY L G + C G+W+ P C
Sbjct: 661 CQPPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRC 717
Score = 32.7 bits (71), Expect = 7.4
Identities = 20/58 (34%), Positives = 27/58 (46%), Gaps = 3/58 (5%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGAR--QRECTLRGDWTLEPPF 57
C P V N + + EN + G YECD+G+ L G + E L+ W LE F
Sbjct: 778 CHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKNCSAEVILKA-WILERAF 834
>EF064746-1|ABK41929.1| 1092|Homo sapiens complement component
(3d/Epstein Barr virus) receptor 2 protein.
Length = 1092
Score = 213 bits (521), Expect = 2e-54
Identities = 188/665 (28%), Positives = 274/665 (41%), Gaps = 81/665 (12%)
Query: 352 TCGSPDKLLNTTI--LGNDYDVGSRIVYKCPEGHMLLGDKSRHC----KKDGFWSGAPPS 405
+CGSP +LN I VG+ I Y C L+G+KS C K DG W P
Sbjct: 22 SCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPK 81
Query: 406 CKYVN--CGGLTPIEDGDVALIDNRT-THGARALYSCRENFTLVGNPERTCGDEGIWDG- 461
C+Y N PI G + + HG ++C+ NF++ GN C +W
Sbjct: 82 CEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWGPT 141
Query: 462 EAPRCLFDW---CPDPPAVSNA---SVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGG 515
P C+ + CP P + N S V G +Y+CE+G++L G + C G
Sbjct: 142 RLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSG 201
Query: 516 AWSGVPPSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGK 575
WS VPP+C+ C + V G A F C+ Y L G C G+
Sbjct: 202 KWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQ 261
Query: 576 ---WSYDIPSCELTSCPE-PEVPSGGYM--EAFDYYVHSTINFHCEAGHK------LIGE 623
W+ +P CE CP P + +G ++ + S + + C+ + LIGE
Sbjct: 262 GVAWT-KMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGE 320
Query: 624 PNLVC----QQDGEWSGDSPTCEY----IDCGKLPTLPYGTM--ELLNGTTHLGSVIQYS 673
L C Q+ G WSG +P CE + C P + G M + T+ +VI ++
Sbjct: 321 STLRCTVDSQKTGTWSGPAPRCELSTSAVQCPH-PQILRGRMVSGQKDRYTYNDTVI-FA 378
Query: 674 CTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRT 733
C + L G + C + W S+P CE+ C P +I++ DR ++R
Sbjct: 379 CMFGFTLKGSKQIRCNAQGTWEPSAPVCEK-ECQAP----PNILNGQKEDRH----MVR- 428
Query: 734 SDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIEN 793
+ G +KY C GY ++GE C G W+ P C+ C GR
Sbjct: 429 ---------FDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGR--- 476
Query: 794 GKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIK 853
+T P + F C E ++L G + + CQ W +E +CKEITCP P I
Sbjct: 477 QLLTKPQH-QFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPV-IY 534
Query: 854 AGSGLLVVTSTLSIGGEAHYQC----ERG--YNLKGHQTRTCIS----KGQWNGTVPVC- 902
G+ G Y C ERG ++L G T C S +G W+G P+C
Sbjct: 535 NGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCK 594
Query: 903 ---IPIDCRSPGNIENG-KIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGE 958
+ + C S +I NG KI + +V + C S + G +C D W E
Sbjct: 595 LSLLAVQC-SHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPE 653
Query: 959 EPSCE 963
P CE
Sbjct: 654 IPVCE 658
Score = 205 bits (500), Expect = 8e-52
Identities = 175/636 (27%), Positives = 257/636 (40%), Gaps = 79/636 (12%)
Query: 372 GSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRTTH 431
G + Y C G++L+G+K +C G WS PP+C+ C L +G V
Sbjct: 176 GLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRV- 234
Query: 432 GARALYSCRENFTLVGNPERTC--GDEGIWDGEAPRCLFDWCPDPPAVSNASVTVN---G 486
G A + C E + L G P C +G+ + P C +CP PP + N N
Sbjct: 235 GVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTKMPVCEEIFCPSPPPILNGRHIGNSLAN 294
Query: 487 HKAGSLASYTC----ENG--HILSGSTSVTCTLG----GAWSGVPPSCKY----VNCGTP 532
GS+ +YTC E G IL G +++ CT+ G WSG P C+ V C P
Sbjct: 295 VSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHP 354
Query: 533 TIHKGSFVL-INGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEP 591
I +G V TY F C + L G++++ CN G W P CE P
Sbjct: 355 QILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKECQAPP 414
Query: 592 EVPSG----GYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCG 647
+ +G +M FD ++I + C G+ L+GE ++ C +G W+ P C+ C
Sbjct: 415 NILNGQKEDRHMVRFD--PGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACE 472
Query: 648 KLPTLPYGTMELLNGTTH--LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIR 705
+LL H + + SC Y+L G V + C W C+EI
Sbjct: 473 AT------GRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEIT 526
Query: 706 CSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKG------YKV 759
C P V N G +L + G V Y C G + +
Sbjct: 527 CPPP--------PVIYNGAHTGSSL----------EDFPYGTTVTYTCNPGPERGVEFSL 568
Query: 760 IGESLSTCEDN----GQWSGTTPTCQY----VDCGNPGRIENG-KVTLPSNATFYGATAF 810
IGES C N G WSG P C+ V C + I NG K++ FY T
Sbjct: 569 IGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHV-HIANGYKISGKEAPYFYNDTVT 627
Query: 811 YQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGE 870
++C + L+G + C+ + TW E P+C E C P + G T G
Sbjct: 628 FKCYSGFTLKGSSQIRCKADNTWDPEIPVC-EKGCQSPPG-LHHGRHTGGNTVFFVSGMT 685
Query: 871 AHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSS 930
Y C+ GY L G+++ C+ G W+ + P C C+ ++ + GS +
Sbjct: 686 VDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRC-EETCQ---HVRQSLQELPAGSRV--EL 739
Query: 931 VEYYCLSQYQRVGPFLRKCLD--DGRWSGEEPSCEL 964
V C YQ G + C D +G W + P C++
Sbjct: 740 VNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKV 775
Score = 202 bits (494), Expect = 4e-51
Identities = 176/651 (27%), Positives = 254/651 (39%), Gaps = 74/651 (11%)
Query: 353 CGSPDKLLNTTILGND--YDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVN 410
C P L + G Y +++ C G L G K C G W + P C+
Sbjct: 351 CPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEK-E 409
Query: 411 CGGLTPIEDG---DVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL 467
C I +G D ++ R G YSC + LVG C EG+W P+C
Sbjct: 410 CQAPPNILNGQKEDRHMV--RFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCK 467
Query: 468 FDWCPDPPAVSNASVTVNGHK-AGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKY 526
C A +T H+ + +C G+ LSGS C W CK
Sbjct: 468 VAACE---ATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKE 524
Query: 527 VNCGTP-TIHKGSFVLIN-GTTTYGSIAQFTCEP------DYWLNGAEELVCNRD----G 574
+ C P I+ G+ + YG+ +TC P ++ L G + C + G
Sbjct: 525 ITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERG 584
Query: 575 KWSYDIPSCELT----SCPEPEVPSGGYMEAFD--YYVHSTINFHCEAGHKLIGEPNLVC 628
WS P C+L+ C + +G + + Y+ + T+ F C +G L G + C
Sbjct: 585 TWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRC 644
Query: 629 QQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHL-GSVIQYSCTTNYRLVGPVRRT 687
+ D W + P CE C P L +G N + G + Y+C Y LVG
Sbjct: 645 KADNTWDPEIPVCEK-GCQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIH 703
Query: 688 CTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGA 747
C WS S+PRCEE C +S+ + R L+ TS
Sbjct: 704 CMPSGNWSPSAPRCEET-CQH---VRQSLQELPAGSRVE---LVNTS------------- 743
Query: 748 LVKYRCEKGYKVIGESLSTCED--NGQWSGTTPTCQYVDCGNPGRIENGKVT-LPSNATF 804
C+ GY++ G + C+D NG W P C+ + C P I NGK T + +
Sbjct: 744 -----CQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFL 798
Query: 805 YGATAFYQCDENWELEGVIRRMCQEN----GTWSLEPPICKE---IT-CPDPSAQIKAGS 856
YG Y+CD+ + L G + C+ + G+WS P C +T CP+P ++K G
Sbjct: 799 YGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNP--EVKHGY 856
Query: 857 GLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIP---IDCRSPGNI 913
L S S + C G+ + G + C + W VP CI I C P
Sbjct: 857 KLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPPKT 916
Query: 914 ENGKIVISNGSTLF-GSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
NG N + G S+ Y C Y VG L C +G WS P C+
Sbjct: 917 PNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCK 967
Score = 188 bits (458), Expect = 9e-47
Identities = 162/626 (25%), Positives = 247/626 (39%), Gaps = 71/626 (11%)
Query: 369 YDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNR 428
+D G+ I Y C G++L+G++S C +G W+ P CK C E L+
Sbjct: 429 FDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAAC------EATGRQLLTKP 482
Query: 429 TTHGAR--ALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVT--- 483
R SC E + L G+ + C W E C CP PP + N + T
Sbjct: 483 QHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSS 542
Query: 484 VNGHKAGSLASYTCENG------HILSGSTSVTCTLG----GAWSGVPPSCKY----VNC 529
+ G+ +YTC G L G +++ CT G WSG P CK V C
Sbjct: 543 LEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQC 602
Query: 530 GTPTIHKGSFVLINGTTT---YGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELT 586
+H + I+G Y F C + L G+ ++ C D W +IP CE
Sbjct: 603 SH--VHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKG 660
Query: 587 SCPEPEVPSGGYMEAFDYYVHS--TINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYI 644
P + G + + S T+++ C+ G+ L+G ++ C G WS +P CE
Sbjct: 661 CQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRCEET 720
Query: 645 DCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTC--TEEFQWSDSSPRCE 702
C + EL G+ ++ SC Y+L G + C E W P C+
Sbjct: 721 -CQHVRQ---SLQELPAGSRV--ELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCK 774
Query: 703 EIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGE 762
I C P V V G HT + ++N GN V Y C++G+ ++GE
Sbjct: 775 VIHCHPPPVI------VNGK-----HTGMM-AENFLYGNE------VSYECDQGFYLLGE 816
Query: 763 SLSTCEDN----GQWSGTTPTC----QYVDCGNPGRIENGKVTLPSNATFYGATAFYQCD 814
C + G WSG +P C C NP K+ +A + + C+
Sbjct: 817 KKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCN 876
Query: 815 ENWELEGVIRRMCQENGTWSLEPPICKE---ITCPDPSAQIKAGSGLLVVTSTLSIGGEA 871
+ + G C + TW P C + I CP P + G+ + S G
Sbjct: 877 PGFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPP-KTPNGNHTGGNIARFSPGMSI 935
Query: 872 HYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIEN-GKIVISNGSTLFGSS 930
Y C++GY L G C +G W+ P C ++C SP +++ K + +G+
Sbjct: 936 LYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAV 995
Query: 931 VEYYCLSQYQRVGPFLRKCLDDGRWS 956
V C Y G +C D +W+
Sbjct: 996 VTLECEDGYMLEGSPQSQCQSDHQWN 1021
Score = 178 bits (433), Expect = 1e-43
Identities = 159/612 (25%), Positives = 239/612 (39%), Gaps = 81/612 (13%)
Query: 404 PSCKYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTC----GDEGIW 459
P ++CG PI +G ++ G YSC F L+G C +G W
Sbjct: 16 PGVLGISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTW 75
Query: 460 DGEAPRC----LFDWCPDPPAVSNASVT-VNGHKAGSLASYTCENGHILSGSTSVTCTLG 514
D AP+C + CP+P + ++ G ++ C+ ++G+ SV C
Sbjct: 76 DKPAPKCEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQAN 135
Query: 515 GAWSGVP-PSCKYV---NC-GTPTIHKGSFVLIN-GTTTYGSIAQFTCEPDYWLNGAEEL 568
W P+C V C P IH G N G+ G ++CE Y L G + +
Sbjct: 136 NMWGPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKII 195
Query: 569 VCNRDGKWSYDIPSCELTSCPE-PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLV 627
C GKWS P+CE C P+G E V T NF C+ G++L G P+
Sbjct: 196 NCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSR 255
Query: 628 CQQDGE---WSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHL--GSVIQYSCT------T 676
C G+ W+ P CE I C P + G + N ++ GS++ Y+C
Sbjct: 256 CVIAGQGVAWT-KMPVCEEIFCPSPPPILNG-RHIGNSLANVSYGSIVTYTCDPDPEEGV 313
Query: 677 NYRLVGPVRRTCTEEFQ----WSDSSPRCE----EIRCSDPIVAEKSIVSVTGNDRSHGH 728
N+ L+G CT + Q WS +PRCE ++C P + +VS + ++
Sbjct: 314 NFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYTYND 373
Query: 729 TLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNP 788
T+I + C G+ + G C G W + P C+ +C P
Sbjct: 374 TVI-------------------FACMFGFTLKGSKQIRCNAQGTWEPSAPVCE-KECQAP 413
Query: 789 GRIENGKVTLPSNATFYGATAF-YQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPD 847
I NG+ F T+ Y C+ + L G C G W+ P CK C
Sbjct: 414 PNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACE- 472
Query: 848 PSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDC 907
G LL + + + C GY L G + C W + +C I C
Sbjct: 473 -----ATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITC 527
Query: 908 RSPGNIENGKIVISNGSTL----FGSSVEYYCLS------QYQRVGPFLRKCLDD----G 953
P I NG GS+L +G++V Y C ++ +G +C + G
Sbjct: 528 PPPPVIYNG---AHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERG 584
Query: 954 RWSGEEPSCELA 965
WSG P C+L+
Sbjct: 585 TWSGPAPLCKLS 596
Score = 177 bits (431), Expect = 2e-43
Identities = 152/564 (26%), Positives = 221/564 (39%), Gaps = 71/564 (12%)
Query: 379 CPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDG-DVALIDNRTTHGARALY 437
C EG+ L G + C+ W CK + C I +G +G Y
Sbjct: 495 CGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTY 554
Query: 438 SCREN------FTLVGNPERTCG----DEGIWDGEAPRCLFDWCPDPPAVSNASVTV-NG 486
+C F+L+G C + G W G AP C AV + V + NG
Sbjct: 555 TCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLL----AVQCSHVHIANG 610
Query: 487 HK-AGSLASY--------TCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTIHKG 537
+K +G A Y C +G L GS+ + C W P C+ P +H G
Sbjct: 611 YKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKGCQSPPGLHHG 670
Query: 538 SFVLINGTTTY---GSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPE---- 590
G T + G +TC+P Y L G + + C G WS P CE T C
Sbjct: 671 RHT--GGNTVFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRCEET-CQHVRQS 727
Query: 591 -PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQ--QDGEWSGDSPTCEYIDCG 647
E+P+G +E +N C+ G++L G +CQ ++G W P C+ I C
Sbjct: 728 LQELPAGSRVEL--------VNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCH 779
Query: 648 KLPTLPYGTMELLNGTTHL-GSVIQYSCTTNYRLVGPVRRTCTEEFQ----WSDSSPRCE 702
P + G + L G+ + Y C + L+G + C + + WS SP+C
Sbjct: 780 PPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQC- 838
Query: 703 EIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGE 762
+R S P+ + HG+ L +T + Y +V C G+ + G
Sbjct: 839 -LR-SPPVTR------CPNPEVKHGYKLNKTH------SAYSHNDIVYVDCNPGFIMNGS 884
Query: 763 SLSTCEDNGQWSGTTPTC---QYVDCGNPGRIENGKVTLPSNATFY-GATAFYQCDENWE 818
+ C + W PTC ++ C P + NG T + A F G + Y CD+ +
Sbjct: 885 RVIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYL 944
Query: 819 LEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERG 878
L G +C GTWS P CKE+ C P+ GL G +CE G
Sbjct: 945 LVGEALLLCTHEGTWSQPAPHCKEVNCSSPADMDGIQKGL-EPRKMYQYGAVVTLECEDG 1003
Query: 879 YNLKGHQTRTCISKGQWNGTVPVC 902
Y L+G C S QWN + VC
Sbjct: 1004 YMLEGSPQSQCQSDHQWNPPLAVC 1027
Score = 167 bits (406), Expect = 2e-40
Identities = 138/483 (28%), Positives = 203/483 (42%), Gaps = 56/483 (11%)
Query: 520 VPPSCKYVNCGTPT-IHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVC----NRDG 574
V P ++CG+P I G + G++ +++C + L G + L+C DG
Sbjct: 14 VAPGVLGISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDG 73
Query: 575 KWSYDIPSCEL----TSCPEPEVPSGGYMEAFDYYVHS-TINFHCEAGHKLIGEPNLVCQ 629
W P CE +SCPEP VP G + Y H ++ F C+ + G ++ CQ
Sbjct: 74 TWDKPAPKCEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQ 133
Query: 630 QDGEWSGDS-PTCEYI---DCGKLPTLPYGTMELLN-GTTHLGSVIQYSCTTNYRLVGPV 684
+ W PTC + +C LP + G N G+ G + YSC + Y LVG
Sbjct: 134 ANNMWGPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEK 193
Query: 685 RRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYR 744
C +WS P CEE RC KS+ L R
Sbjct: 194 IINCLSSGKWSAVPPTCEEARC-------KSLGRFPNGKVKEPPIL-------------R 233
Query: 745 IGALVKYRCEKGYKVIGESLSTCEDNGQWSGTT--PTCQYVDCGNPGRIENGKVTLPSNA 802
+G + C++GY++ G S C GQ T P C+ + C +P I NG+ S A
Sbjct: 234 VGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTKMPVCEEIFCPSPPPILNGRHIGNSLA 293
Query: 803 TF-YGATAFYQCDE------NWELEGVIRRMC----QENGTWSLEPPICK----EITCPD 847
YG+ Y CD N+ L G C Q+ GTWS P C+ + CP
Sbjct: 294 NVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPH 353
Query: 848 PSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDC 907
P QI G + + + C G+ LKG + C ++G W + PVC +C
Sbjct: 354 P--QILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEK-EC 410
Query: 908 RSPGNIENGKIVISNGSTLF-GSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCELAT 966
++P NI NG+ + G+S++Y C Y VG +C +G W+ P C++A
Sbjct: 411 QAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAA 470
Query: 967 NEA 969
EA
Sbjct: 471 CEA 473
Score = 166 bits (403), Expect = 4e-40
Identities = 137/554 (24%), Positives = 222/554 (40%), Gaps = 63/554 (11%)
Query: 352 TCGSPDKLLNTTILGN---DYDVGSRIVYKCPEG------HMLLGDKSRHCKKD----GF 398
TC P + N G+ D+ G+ + Y C G L+G+ + C + G
Sbjct: 526 TCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGT 585
Query: 399 WSGAPPSCKY----VNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCG 454
WSG P CK V C + ++ + + + C FTL G+ + C
Sbjct: 586 WSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCK 645
Query: 455 DEGIWDGEAPRCLFDWCPDPPAVSNASVTVNG---HKAGSLASYTCENGHILSGSTSVTC 511
+ WD E P C C PP + + T +G YTC+ G++L G+ S+ C
Sbjct: 646 ADNTWDPEIPVCE-KGCQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIHC 704
Query: 512 TLGGAWSGVPPSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCN 571
G WS P C+ C + + L G+ + +C+ Y L G +C
Sbjct: 705 MPSGNWSPSAPRCEET-C--QHVRQSLQELPAGSRV--ELVNTSCQDGYQLTGHAYQMCQ 759
Query: 572 --RDGKWSYDIPSCELTSC-PEPEVPSGGY--MEAFDYYVHSTINFHCEAGHKLIGEPNL 626
+G W IP C++ C P P + +G + M A ++ + +++ C+ G L+GE L
Sbjct: 760 DAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKL 819
Query: 627 VCQQD----GEWSGDSPTC----EYIDCGKLPTLPYG-TMELLNGTTHLGSVIQYSCTTN 677
C+ D G WSG SP C C P + +G + + ++ C
Sbjct: 820 QCRSDSKGHGSWSGPSPQCLRSPPVTRCPN-PEVKHGYKLNKTHSAYSHNDIVYVDCNPG 878
Query: 678 YRLVGPVRRTCTEEFQWSDSSPRCEE---IRCSDPIVAEKSIVSVTGNDRSHGHTLIRTS 734
+ + G C + W P C + I C P T N G + R S
Sbjct: 879 FIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPP--------PKTPNGNHTGGNIARFS 930
Query: 735 DNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENG 794
G + Y C++GY ++GE+L C G WS P C+ V+C +P ++
Sbjct: 931 P----------GMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVNCSSPADMDGI 980
Query: 795 KVTL-PSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIK 853
+ L P YGA +C++ + LEG + CQ + W+ +C+ + I
Sbjct: 981 QKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSDHQWNPPLAVCRSRSLAPVLCGIA 1040
Query: 854 AGSGLLVVTSTLSI 867
AG LL +++
Sbjct: 1041 AGLILLTFLIVITL 1054
Score = 40.3 bits (90), Expect = 0.037
Identities = 23/75 (30%), Positives = 29/75 (38%), Gaps = 1/75 (1%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTN 61
C P PN + N G +Y CD+GY L G CT G W+ P C
Sbjct: 910 CPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHC-KE 968
Query: 62 VAFRKPANQSTTVRG 76
V PA+ +G
Sbjct: 969 VNCSSPADMDGIQKG 983
Score = 38.7 bits (86), Expect = 0.11
Identities = 19/56 (33%), Positives = 25/56 (44%), Gaps = 2/56 (3%)
Query: 5 PAVPP--NARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
PA+P N + N +I G Y C+ GY L G + C G W+ PP C
Sbjct: 155 PALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTC 210
Score = 36.3 bits (80), Expect = 0.60
Identities = 19/54 (35%), Positives = 24/54 (44%), Gaps = 3/54 (5%)
Query: 8 PPNARVSIPNEENIVA---GTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
PPN + ++V GT Y C+ GY L G +CT G WT P C
Sbjct: 413 PPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQC 466
Score = 36.3 bits (80), Expect = 0.60
Identities = 19/61 (31%), Positives = 28/61 (45%), Gaps = 4/61 (6%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTL----RGDWTLEPPF 57
C P V N + + EN + G YECD+G+ L G ++ +C G W+ P
Sbjct: 778 CHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQ 837
Query: 58 C 58
C
Sbjct: 838 C 838
Score = 34.7 bits (76), Expect = 1.8
Identities = 16/58 (27%), Positives = 26/58 (44%), Gaps = 1/58 (1%)
Query: 1 RCGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
+C HP + VS + T+ ++ C G+ L G++Q C +G W P C
Sbjct: 350 QCPHPQILRGRMVSGQKDRYTYNDTV-IFACMFGFTLKGSKQIRCNAQGTWEPSAPVC 406
Score = 34.7 bits (76), Expect = 1.8
Identities = 18/57 (31%), Positives = 24/57 (42%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C P + R + N V+G Y CD GY L G + C G+W+ P C
Sbjct: 661 CQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRC 717
>AL691452-8|CAI16729.1| 1092|Homo sapiens complement component
(3d/Epstein Barr virus) receptor 2 protein.
Length = 1092
Score = 213 bits (521), Expect = 2e-54
Identities = 188/665 (28%), Positives = 274/665 (41%), Gaps = 81/665 (12%)
Query: 352 TCGSPDKLLNTTI--LGNDYDVGSRIVYKCPEGHMLLGDKSRHC----KKDGFWSGAPPS 405
+CGSP +LN I VG+ I Y C L+G+KS C K DG W P
Sbjct: 22 SCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPK 81
Query: 406 CKYVN--CGGLTPIEDGDVALIDNRT-THGARALYSCRENFTLVGNPERTCGDEGIWDG- 461
C+Y N PI G + + HG ++C+ NF++ GN C +W
Sbjct: 82 CEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWGPT 141
Query: 462 EAPRCLFDW---CPDPPAVSNA---SVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGG 515
P C+ + CP P + N S V G +Y+CE+G++L G + C G
Sbjct: 142 RLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSG 201
Query: 516 AWSGVPPSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGK 575
WS VPP+C+ C + V G A F C+ Y L G C G+
Sbjct: 202 KWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQ 261
Query: 576 ---WSYDIPSCELTSCPE-PEVPSGGYM--EAFDYYVHSTINFHCEAGHK------LIGE 623
W+ +P CE CP P + +G ++ + S + + C+ + LIGE
Sbjct: 262 GVAWT-KMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGE 320
Query: 624 PNLVC----QQDGEWSGDSPTCEY----IDCGKLPTLPYGTM--ELLNGTTHLGSVIQYS 673
L C Q+ G WSG +P CE + C P + G M + T+ +VI ++
Sbjct: 321 STLRCTVDSQKTGTWSGPAPRCELSTSAVQCPH-PQILRGRMVSGQKDRYTYNDTVI-FA 378
Query: 674 CTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRT 733
C + L G + C + W S+P CE+ C P +I++ DR ++R
Sbjct: 379 CMFGFTLKGSKQIRCNAQGTWEPSAPVCEK-ECQAP----PNILNGQKEDRH----MVR- 428
Query: 734 SDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIEN 793
+ G +KY C GY ++GE C G W+ P C+ C GR
Sbjct: 429 ---------FDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGR--- 476
Query: 794 GKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIK 853
+T P + F C E ++L G + + CQ W +E +CKEITCP P I
Sbjct: 477 QLLTKPQH-QFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPV-IY 534
Query: 854 AGSGLLVVTSTLSIGGEAHYQC----ERG--YNLKGHQTRTCIS----KGQWNGTVPVC- 902
G+ G Y C ERG ++L G T C S +G W+G P+C
Sbjct: 535 NGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCK 594
Query: 903 ---IPIDCRSPGNIENG-KIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGE 958
+ + C S +I NG KI + +V + C S + G +C D W E
Sbjct: 595 LSLLAVQC-SHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPE 653
Query: 959 EPSCE 963
P CE
Sbjct: 654 IPVCE 658
Score = 205 bits (500), Expect = 8e-52
Identities = 175/636 (27%), Positives = 257/636 (40%), Gaps = 79/636 (12%)
Query: 372 GSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRTTH 431
G + Y C G++L+G+K +C G WS PP+C+ C L +G V
Sbjct: 176 GLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRV- 234
Query: 432 GARALYSCRENFTLVGNPERTC--GDEGIWDGEAPRCLFDWCPDPPAVSNASVTVN---G 486
G A + C E + L G P C +G+ + P C +CP PP + N N
Sbjct: 235 GVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTKMPVCEEIFCPSPPPILNGRHIGNSLAN 294
Query: 487 HKAGSLASYTC----ENG--HILSGSTSVTCTLG----GAWSGVPPSCKY----VNCGTP 532
GS+ +YTC E G IL G +++ CT+ G WSG P C+ V C P
Sbjct: 295 VSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHP 354
Query: 533 TIHKGSFVL-INGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEP 591
I +G V TY F C + L G++++ CN G W P CE P
Sbjct: 355 QILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKECQAPP 414
Query: 592 EVPSG----GYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCG 647
+ +G +M FD ++I + C G+ L+GE ++ C +G W+ P C+ C
Sbjct: 415 NILNGQKEDRHMVRFD--PGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACE 472
Query: 648 KLPTLPYGTMELLNGTTH--LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIR 705
+LL H + + SC Y+L G V + C W C+EI
Sbjct: 473 AT------GRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEIT 526
Query: 706 CSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKG------YKV 759
C P V N G +L + G V Y C G + +
Sbjct: 527 CPPP--------PVIYNGAHTGSSL----------EDFPYGTTVTYTCNPGPERGVEFSL 568
Query: 760 IGESLSTCEDN----GQWSGTTPTCQY----VDCGNPGRIENG-KVTLPSNATFYGATAF 810
IGES C N G WSG P C+ V C + I NG K++ FY T
Sbjct: 569 IGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHV-HIANGYKISGKEAPYFYNDTVT 627
Query: 811 YQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGE 870
++C + L+G + C+ + TW E P+C E C P + G T G
Sbjct: 628 FKCYSGFTLKGSSQIRCKADNTWDPEIPVC-EKGCQSPPG-LHHGRHTGGNTVFFVSGMT 685
Query: 871 AHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSS 930
Y C+ GY L G+++ C+ G W+ + P C C+ ++ + GS +
Sbjct: 686 VDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRC-EETCQ---HVRQSLQELPAGSRV--EL 739
Query: 931 VEYYCLSQYQRVGPFLRKCLD--DGRWSGEEPSCEL 964
V C YQ G + C D +G W + P C++
Sbjct: 740 VNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKV 775
Score = 202 bits (494), Expect = 4e-51
Identities = 176/651 (27%), Positives = 254/651 (39%), Gaps = 74/651 (11%)
Query: 353 CGSPDKLLNTTILGND--YDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVN 410
C P L + G Y +++ C G L G K C G W + P C+
Sbjct: 351 CPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEK-E 409
Query: 411 CGGLTPIEDG---DVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL 467
C I +G D ++ R G YSC + LVG C EG+W P+C
Sbjct: 410 CQAPPNILNGQKEDRHMV--RFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCK 467
Query: 468 FDWCPDPPAVSNASVTVNGHK-AGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKY 526
C A +T H+ + +C G+ LSGS C W CK
Sbjct: 468 VAACE---ATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKE 524
Query: 527 VNCGTP-TIHKGSFVLIN-GTTTYGSIAQFTCEP------DYWLNGAEELVCNRD----G 574
+ C P I+ G+ + YG+ +TC P ++ L G + C + G
Sbjct: 525 ITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERG 584
Query: 575 KWSYDIPSCELT----SCPEPEVPSGGYMEAFD--YYVHSTINFHCEAGHKLIGEPNLVC 628
WS P C+L+ C + +G + + Y+ + T+ F C +G L G + C
Sbjct: 585 TWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRC 644
Query: 629 QQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHL-GSVIQYSCTTNYRLVGPVRRT 687
+ D W + P CE C P L +G N + G + Y+C Y LVG
Sbjct: 645 KADNTWDPEIPVCEK-GCQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIH 703
Query: 688 CTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGA 747
C WS S+PRCEE C +S+ + R L+ TS
Sbjct: 704 CMPSGNWSPSAPRCEET-CQH---VRQSLQELPAGSRVE---LVNTS------------- 743
Query: 748 LVKYRCEKGYKVIGESLSTCED--NGQWSGTTPTCQYVDCGNPGRIENGKVT-LPSNATF 804
C+ GY++ G + C+D NG W P C+ + C P I NGK T + +
Sbjct: 744 -----CQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFL 798
Query: 805 YGATAFYQCDENWELEGVIRRMCQEN----GTWSLEPPICKE---IT-CPDPSAQIKAGS 856
YG Y+CD+ + L G + C+ + G+WS P C +T CP+P ++K G
Sbjct: 799 YGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNP--EVKHGY 856
Query: 857 GLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIP---IDCRSPGNI 913
L S S + C G+ + G + C + W VP CI I C P
Sbjct: 857 KLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPPKT 916
Query: 914 ENGKIVISNGSTLF-GSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
NG N + G S+ Y C Y VG L C +G WS P C+
Sbjct: 917 PNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCK 967
Score = 188 bits (458), Expect = 9e-47
Identities = 162/626 (25%), Positives = 247/626 (39%), Gaps = 71/626 (11%)
Query: 369 YDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNR 428
+D G+ I Y C G++L+G++S C +G W+ P CK C E L+
Sbjct: 429 FDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAAC------EATGRQLLTKP 482
Query: 429 TTHGAR--ALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVT--- 483
R SC E + L G+ + C W E C CP PP + N + T
Sbjct: 483 QHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSS 542
Query: 484 VNGHKAGSLASYTCENG------HILSGSTSVTCTLG----GAWSGVPPSCKY----VNC 529
+ G+ +YTC G L G +++ CT G WSG P CK V C
Sbjct: 543 LEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQC 602
Query: 530 GTPTIHKGSFVLINGTTT---YGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELT 586
+H + I+G Y F C + L G+ ++ C D W +IP CE
Sbjct: 603 SH--VHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKG 660
Query: 587 SCPEPEVPSGGYMEAFDYYVHS--TINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYI 644
P + G + + S T+++ C+ G+ L+G ++ C G WS +P CE
Sbjct: 661 CQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRCEET 720
Query: 645 DCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTC--TEEFQWSDSSPRCE 702
C + EL G+ ++ SC Y+L G + C E W P C+
Sbjct: 721 -CQHVRQ---SLQELPAGSRV--ELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCK 774
Query: 703 EIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGE 762
I C P V V G HT + ++N GN V Y C++G+ ++GE
Sbjct: 775 VIHCHPPPVI------VNGK-----HTGMM-AENFLYGNE------VSYECDQGFYLLGE 816
Query: 763 SLSTCEDN----GQWSGTTPTC----QYVDCGNPGRIENGKVTLPSNATFYGATAFYQCD 814
C + G WSG +P C C NP K+ +A + + C+
Sbjct: 817 KKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCN 876
Query: 815 ENWELEGVIRRMCQENGTWSLEPPICKE---ITCPDPSAQIKAGSGLLVVTSTLSIGGEA 871
+ + G C + TW P C + I CP P + G+ + S G
Sbjct: 877 PGFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPP-KTPNGNHTGGNIARFSPGMSI 935
Query: 872 HYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIEN-GKIVISNGSTLFGSS 930
Y C++GY L G C +G W+ P C ++C SP +++ K + +G+
Sbjct: 936 LYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAV 995
Query: 931 VEYYCLSQYQRVGPFLRKCLDDGRWS 956
V C Y G +C D +W+
Sbjct: 996 VTLECEDGYMLEGSPQSQCQSDHQWN 1021
Score = 178 bits (433), Expect = 1e-43
Identities = 159/612 (25%), Positives = 239/612 (39%), Gaps = 81/612 (13%)
Query: 404 PSCKYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTC----GDEGIW 459
P ++CG PI +G ++ G YSC F L+G C +G W
Sbjct: 16 PGVLGISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTW 75
Query: 460 DGEAPRC----LFDWCPDPPAVSNASVT-VNGHKAGSLASYTCENGHILSGSTSVTCTLG 514
D AP+C + CP+P + ++ G ++ C+ ++G+ SV C
Sbjct: 76 DKPAPKCEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQAN 135
Query: 515 GAWSGVP-PSCKYV---NC-GTPTIHKGSFVLIN-GTTTYGSIAQFTCEPDYWLNGAEEL 568
W P+C V C P IH G N G+ G ++CE Y L G + +
Sbjct: 136 NMWGPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKII 195
Query: 569 VCNRDGKWSYDIPSCELTSCPE-PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLV 627
C GKWS P+CE C P+G E V T NF C+ G++L G P+
Sbjct: 196 NCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSR 255
Query: 628 CQQDGE---WSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHL--GSVIQYSCT------T 676
C G+ W+ P CE I C P + G + N ++ GS++ Y+C
Sbjct: 256 CVIAGQGVAWT-KMPVCEEIFCPSPPPILNG-RHIGNSLANVSYGSIVTYTCDPDPEEGV 313
Query: 677 NYRLVGPVRRTCTEEFQ----WSDSSPRCE----EIRCSDPIVAEKSIVSVTGNDRSHGH 728
N+ L+G CT + Q WS +PRCE ++C P + +VS + ++
Sbjct: 314 NFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYTYND 373
Query: 729 TLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNP 788
T+I + C G+ + G C G W + P C+ +C P
Sbjct: 374 TVI-------------------FACMFGFTLKGSKQIRCNAQGTWEPSAPVCE-KECQAP 413
Query: 789 GRIENGKVTLPSNATFYGATAF-YQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPD 847
I NG+ F T+ Y C+ + L G C G W+ P CK C
Sbjct: 414 PNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACE- 472
Query: 848 PSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDC 907
G LL + + + C GY L G + C W + +C I C
Sbjct: 473 -----ATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITC 527
Query: 908 RSPGNIENGKIVISNGSTL----FGSSVEYYCLS------QYQRVGPFLRKCLDD----G 953
P I NG GS+L +G++V Y C ++ +G +C + G
Sbjct: 528 PPPPVIYNG---AHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERG 584
Query: 954 RWSGEEPSCELA 965
WSG P C+L+
Sbjct: 585 TWSGPAPLCKLS 596
Score = 177 bits (431), Expect = 2e-43
Identities = 152/564 (26%), Positives = 221/564 (39%), Gaps = 71/564 (12%)
Query: 379 CPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDG-DVALIDNRTTHGARALY 437
C EG+ L G + C+ W CK + C I +G +G Y
Sbjct: 495 CGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTY 554
Query: 438 SCREN------FTLVGNPERTCG----DEGIWDGEAPRCLFDWCPDPPAVSNASVTV-NG 486
+C F+L+G C + G W G AP C AV + V + NG
Sbjct: 555 TCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLL----AVQCSHVHIANG 610
Query: 487 HK-AGSLASY--------TCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTIHKG 537
+K +G A Y C +G L GS+ + C W P C+ P +H G
Sbjct: 611 YKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKGCQSPPGLHHG 670
Query: 538 SFVLINGTTTY---GSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPE---- 590
G T + G +TC+P Y L G + + C G WS P CE T C
Sbjct: 671 RHT--GGNTVFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRCEET-CQHVRQS 727
Query: 591 -PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQ--QDGEWSGDSPTCEYIDCG 647
E+P+G +E +N C+ G++L G +CQ ++G W P C+ I C
Sbjct: 728 LQELPAGSRVEL--------VNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCH 779
Query: 648 KLPTLPYGTMELLNGTTHL-GSVIQYSCTTNYRLVGPVRRTCTEEFQ----WSDSSPRCE 702
P + G + L G+ + Y C + L+G + C + + WS SP+C
Sbjct: 780 PPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQC- 838
Query: 703 EIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGE 762
+R S P+ + HG+ L +T + Y +V C G+ + G
Sbjct: 839 -LR-SPPVTR------CPNPEVKHGYKLNKTH------SAYSHNDIVYVDCNPGFIMNGS 884
Query: 763 SLSTCEDNGQWSGTTPTC---QYVDCGNPGRIENGKVTLPSNATFY-GATAFYQCDENWE 818
+ C + W PTC ++ C P + NG T + A F G + Y CD+ +
Sbjct: 885 RVIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYL 944
Query: 819 LEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERG 878
L G +C GTWS P CKE+ C P+ GL G +CE G
Sbjct: 945 LVGEALLLCTHEGTWSQPAPHCKEVNCSSPADMDGIQKGL-EPRKMYQYGAVVTLECEDG 1003
Query: 879 YNLKGHQTRTCISKGQWNGTVPVC 902
Y L+G C S QWN + VC
Sbjct: 1004 YMLEGSPQSQCQSDHQWNPPLAVC 1027
Score = 167 bits (406), Expect = 2e-40
Identities = 138/483 (28%), Positives = 203/483 (42%), Gaps = 56/483 (11%)
Query: 520 VPPSCKYVNCGTPT-IHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVC----NRDG 574
V P ++CG+P I G + G++ +++C + L G + L+C DG
Sbjct: 14 VAPGVLGISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDG 73
Query: 575 KWSYDIPSCEL----TSCPEPEVPSGGYMEAFDYYVHS-TINFHCEAGHKLIGEPNLVCQ 629
W P CE +SCPEP VP G + Y H ++ F C+ + G ++ CQ
Sbjct: 74 TWDKPAPKCEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQ 133
Query: 630 QDGEWSGDS-PTCEYI---DCGKLPTLPYGTMELLN-GTTHLGSVIQYSCTTNYRLVGPV 684
+ W PTC + +C LP + G N G+ G + YSC + Y LVG
Sbjct: 134 ANNMWGPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEK 193
Query: 685 RRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYR 744
C +WS P CEE RC KS+ L R
Sbjct: 194 IINCLSSGKWSAVPPTCEEARC-------KSLGRFPNGKVKEPPIL-------------R 233
Query: 745 IGALVKYRCEKGYKVIGESLSTCEDNGQWSGTT--PTCQYVDCGNPGRIENGKVTLPSNA 802
+G + C++GY++ G S C GQ T P C+ + C +P I NG+ S A
Sbjct: 234 VGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTKMPVCEEIFCPSPPPILNGRHIGNSLA 293
Query: 803 TF-YGATAFYQCDE------NWELEGVIRRMC----QENGTWSLEPPICK----EITCPD 847
YG+ Y CD N+ L G C Q+ GTWS P C+ + CP
Sbjct: 294 NVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPH 353
Query: 848 PSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDC 907
P QI G + + + C G+ LKG + C ++G W + PVC +C
Sbjct: 354 P--QILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEK-EC 410
Query: 908 RSPGNIENGKIVISNGSTLF-GSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCELAT 966
++P NI NG+ + G+S++Y C Y VG +C +G W+ P C++A
Sbjct: 411 QAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAA 470
Query: 967 NEA 969
EA
Sbjct: 471 CEA 473
Score = 166 bits (403), Expect = 4e-40
Identities = 137/554 (24%), Positives = 222/554 (40%), Gaps = 63/554 (11%)
Query: 352 TCGSPDKLLNTTILGN---DYDVGSRIVYKCPEG------HMLLGDKSRHCKKD----GF 398
TC P + N G+ D+ G+ + Y C G L+G+ + C + G
Sbjct: 526 TCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGT 585
Query: 399 WSGAPPSCKY----VNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCG 454
WSG P CK V C + ++ + + + C FTL G+ + C
Sbjct: 586 WSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCK 645
Query: 455 DEGIWDGEAPRCLFDWCPDPPAVSNASVTVNG---HKAGSLASYTCENGHILSGSTSVTC 511
+ WD E P C C PP + + T +G YTC+ G++L G+ S+ C
Sbjct: 646 ADNTWDPEIPVCE-KGCQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIHC 704
Query: 512 TLGGAWSGVPPSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCN 571
G WS P C+ C + + L G+ + +C+ Y L G +C
Sbjct: 705 MPSGNWSPSAPRCEET-C--QHVRQSLQELPAGSRV--ELVNTSCQDGYQLTGHAYQMCQ 759
Query: 572 --RDGKWSYDIPSCELTSC-PEPEVPSGGY--MEAFDYYVHSTINFHCEAGHKLIGEPNL 626
+G W IP C++ C P P + +G + M A ++ + +++ C+ G L+GE L
Sbjct: 760 DAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKL 819
Query: 627 VCQQD----GEWSGDSPTC----EYIDCGKLPTLPYG-TMELLNGTTHLGSVIQYSCTTN 677
C+ D G WSG SP C C P + +G + + ++ C
Sbjct: 820 QCRSDSKGHGSWSGPSPQCLRSPPVTRCPN-PEVKHGYKLNKTHSAYSHNDIVYVDCNPG 878
Query: 678 YRLVGPVRRTCTEEFQWSDSSPRCEE---IRCSDPIVAEKSIVSVTGNDRSHGHTLIRTS 734
+ + G C + W P C + I C P T N G + R S
Sbjct: 879 FIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPP--------PKTPNGNHTGGNIARFS 930
Query: 735 DNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENG 794
G + Y C++GY ++GE+L C G WS P C+ V+C +P ++
Sbjct: 931 P----------GMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVNCSSPADMDGI 980
Query: 795 KVTL-PSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIK 853
+ L P YGA +C++ + LEG + CQ + W+ +C+ + I
Sbjct: 981 QKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSDHQWNPPLAVCRSRSLAPVLCGIA 1040
Query: 854 AGSGLLVVTSTLSI 867
AG LL +++
Sbjct: 1041 AGLILLTFLIVITL 1054
Score = 40.3 bits (90), Expect = 0.037
Identities = 23/75 (30%), Positives = 29/75 (38%), Gaps = 1/75 (1%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTN 61
C P PN + N G +Y CD+GY L G CT G W+ P C
Sbjct: 910 CPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHC-KE 968
Query: 62 VAFRKPANQSTTVRG 76
V PA+ +G
Sbjct: 969 VNCSSPADMDGIQKG 983
Score = 38.7 bits (86), Expect = 0.11
Identities = 19/56 (33%), Positives = 25/56 (44%), Gaps = 2/56 (3%)
Query: 5 PAVPP--NARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
PA+P N + N +I G Y C+ GY L G + C G W+ PP C
Sbjct: 155 PALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTC 210
Score = 36.3 bits (80), Expect = 0.60
Identities = 19/54 (35%), Positives = 24/54 (44%), Gaps = 3/54 (5%)
Query: 8 PPNARVSIPNEENIVA---GTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
PPN + ++V GT Y C+ GY L G +CT G WT P C
Sbjct: 413 PPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQC 466
Score = 36.3 bits (80), Expect = 0.60
Identities = 19/61 (31%), Positives = 28/61 (45%), Gaps = 4/61 (6%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTL----RGDWTLEPPF 57
C P V N + + EN + G YECD+G+ L G ++ +C G W+ P
Sbjct: 778 CHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQ 837
Query: 58 C 58
C
Sbjct: 838 C 838
Score = 34.7 bits (76), Expect = 1.8
Identities = 16/58 (27%), Positives = 26/58 (44%), Gaps = 1/58 (1%)
Query: 1 RCGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
+C HP + VS + T+ ++ C G+ L G++Q C +G W P C
Sbjct: 350 QCPHPQILRGRMVSGQKDRYTYNDTV-IFACMFGFTLKGSKQIRCNAQGTWEPSAPVC 406
Score = 34.7 bits (76), Expect = 1.8
Identities = 18/57 (31%), Positives = 24/57 (42%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C P + R + N V+G Y CD GY L G + C G+W+ P C
Sbjct: 661 CQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRC 717
>AL391597-5|CAH72950.1| 1092|Homo sapiens complement component
(3d/Epstein Barr virus) receptor 2 protein.
Length = 1092
Score = 213 bits (521), Expect = 2e-54
Identities = 188/665 (28%), Positives = 274/665 (41%), Gaps = 81/665 (12%)
Query: 352 TCGSPDKLLNTTI--LGNDYDVGSRIVYKCPEGHMLLGDKSRHC----KKDGFWSGAPPS 405
+CGSP +LN I VG+ I Y C L+G+KS C K DG W P
Sbjct: 22 SCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPK 81
Query: 406 CKYVN--CGGLTPIEDGDVALIDNRT-THGARALYSCRENFTLVGNPERTCGDEGIWDG- 461
C+Y N PI G + + HG ++C+ NF++ GN C +W
Sbjct: 82 CEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWGPT 141
Query: 462 EAPRCLFDW---CPDPPAVSNA---SVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGG 515
P C+ + CP P + N S V G +Y+CE+G++L G + C G
Sbjct: 142 RLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSG 201
Query: 516 AWSGVPPSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGK 575
WS VPP+C+ C + V G A F C+ Y L G C G+
Sbjct: 202 KWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQ 261
Query: 576 ---WSYDIPSCELTSCPE-PEVPSGGYM--EAFDYYVHSTINFHCEAGHK------LIGE 623
W+ +P CE CP P + +G ++ + S + + C+ + LIGE
Sbjct: 262 GVAWT-KMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGE 320
Query: 624 PNLVC----QQDGEWSGDSPTCEY----IDCGKLPTLPYGTM--ELLNGTTHLGSVIQYS 673
L C Q+ G WSG +P CE + C P + G M + T+ +VI ++
Sbjct: 321 STLRCTVDSQKTGTWSGPAPRCELSTSAVQCPH-PQILRGRMVSGQKDRYTYNDTVI-FA 378
Query: 674 CTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRT 733
C + L G + C + W S+P CE+ C P +I++ DR ++R
Sbjct: 379 CMFGFTLKGSKQIRCNAQGTWEPSAPVCEK-ECQAP----PNILNGQKEDRH----MVR- 428
Query: 734 SDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIEN 793
+ G +KY C GY ++GE C G W+ P C+ C GR
Sbjct: 429 ---------FDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGR--- 476
Query: 794 GKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIK 853
+T P + F C E ++L G + + CQ W +E +CKEITCP P I
Sbjct: 477 QLLTKPQH-QFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPV-IY 534
Query: 854 AGSGLLVVTSTLSIGGEAHYQC----ERG--YNLKGHQTRTCIS----KGQWNGTVPVC- 902
G+ G Y C ERG ++L G T C S +G W+G P+C
Sbjct: 535 NGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCK 594
Query: 903 ---IPIDCRSPGNIENG-KIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGE 958
+ + C S +I NG KI + +V + C S + G +C D W E
Sbjct: 595 LSLLAVQC-SHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPE 653
Query: 959 EPSCE 963
P CE
Sbjct: 654 IPVCE 658
Score = 205 bits (500), Expect = 8e-52
Identities = 175/636 (27%), Positives = 257/636 (40%), Gaps = 79/636 (12%)
Query: 372 GSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRTTH 431
G + Y C G++L+G+K +C G WS PP+C+ C L +G V
Sbjct: 176 GLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRV- 234
Query: 432 GARALYSCRENFTLVGNPERTC--GDEGIWDGEAPRCLFDWCPDPPAVSNASVTVN---G 486
G A + C E + L G P C +G+ + P C +CP PP + N N
Sbjct: 235 GVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTKMPVCEEIFCPSPPPILNGRHIGNSLAN 294
Query: 487 HKAGSLASYTC----ENG--HILSGSTSVTCTLG----GAWSGVPPSCKY----VNCGTP 532
GS+ +YTC E G IL G +++ CT+ G WSG P C+ V C P
Sbjct: 295 VSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHP 354
Query: 533 TIHKGSFVL-INGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEP 591
I +G V TY F C + L G++++ CN G W P CE P
Sbjct: 355 QILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKECQAPP 414
Query: 592 EVPSG----GYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCG 647
+ +G +M FD ++I + C G+ L+GE ++ C +G W+ P C+ C
Sbjct: 415 NILNGQKEDRHMVRFD--PGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACE 472
Query: 648 KLPTLPYGTMELLNGTTH--LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIR 705
+LL H + + SC Y+L G V + C W C+EI
Sbjct: 473 AT------GRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEIT 526
Query: 706 CSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKG------YKV 759
C P V N G +L + G V Y C G + +
Sbjct: 527 CPPP--------PVIYNGAHTGSSL----------EDFPYGTTVTYTCNPGPERGVEFSL 568
Query: 760 IGESLSTCEDN----GQWSGTTPTCQY----VDCGNPGRIENG-KVTLPSNATFYGATAF 810
IGES C N G WSG P C+ V C + I NG K++ FY T
Sbjct: 569 IGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHV-HIANGYKISGKEAPYFYNDTVT 627
Query: 811 YQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGE 870
++C + L+G + C+ + TW E P+C E C P + G T G
Sbjct: 628 FKCYSGFTLKGSSQIRCKADNTWDPEIPVC-EKGCQSPPG-LHHGRHTGGNTVFFVSGMT 685
Query: 871 AHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSS 930
Y C+ GY L G+++ C+ G W+ + P C C+ ++ + GS +
Sbjct: 686 VDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRC-EETCQ---HVRQSLQELPAGSRV--EL 739
Query: 931 VEYYCLSQYQRVGPFLRKCLD--DGRWSGEEPSCEL 964
V C YQ G + C D +G W + P C++
Sbjct: 740 VNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKV 775
Score = 202 bits (494), Expect = 4e-51
Identities = 176/651 (27%), Positives = 254/651 (39%), Gaps = 74/651 (11%)
Query: 353 CGSPDKLLNTTILGND--YDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVN 410
C P L + G Y +++ C G L G K C G W + P C+
Sbjct: 351 CPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEK-E 409
Query: 411 CGGLTPIEDG---DVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL 467
C I +G D ++ R G YSC + LVG C EG+W P+C
Sbjct: 410 CQAPPNILNGQKEDRHMV--RFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCK 467
Query: 468 FDWCPDPPAVSNASVTVNGHK-AGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKY 526
C A +T H+ + +C G+ LSGS C W CK
Sbjct: 468 VAACE---ATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKE 524
Query: 527 VNCGTP-TIHKGSFVLIN-GTTTYGSIAQFTCEP------DYWLNGAEELVCNRD----G 574
+ C P I+ G+ + YG+ +TC P ++ L G + C + G
Sbjct: 525 ITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERG 584
Query: 575 KWSYDIPSCELT----SCPEPEVPSGGYMEAFD--YYVHSTINFHCEAGHKLIGEPNLVC 628
WS P C+L+ C + +G + + Y+ + T+ F C +G L G + C
Sbjct: 585 TWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRC 644
Query: 629 QQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHL-GSVIQYSCTTNYRLVGPVRRT 687
+ D W + P CE C P L +G N + G + Y+C Y LVG
Sbjct: 645 KADNTWDPEIPVCEK-GCQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIH 703
Query: 688 CTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGA 747
C WS S+PRCEE C +S+ + R L+ TS
Sbjct: 704 CMPSGNWSPSAPRCEET-CQH---VRQSLQELPAGSRVE---LVNTS------------- 743
Query: 748 LVKYRCEKGYKVIGESLSTCED--NGQWSGTTPTCQYVDCGNPGRIENGKVT-LPSNATF 804
C+ GY++ G + C+D NG W P C+ + C P I NGK T + +
Sbjct: 744 -----CQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFL 798
Query: 805 YGATAFYQCDENWELEGVIRRMCQEN----GTWSLEPPICKE---IT-CPDPSAQIKAGS 856
YG Y+CD+ + L G + C+ + G+WS P C +T CP+P ++K G
Sbjct: 799 YGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNP--EVKHGY 856
Query: 857 GLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIP---IDCRSPGNI 913
L S S + C G+ + G + C + W VP CI I C P
Sbjct: 857 KLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPPKT 916
Query: 914 ENGKIVISNGSTLF-GSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
NG N + G S+ Y C Y VG L C +G WS P C+
Sbjct: 917 PNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCK 967
Score = 188 bits (458), Expect = 9e-47
Identities = 162/626 (25%), Positives = 247/626 (39%), Gaps = 71/626 (11%)
Query: 369 YDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNR 428
+D G+ I Y C G++L+G++S C +G W+ P CK C E L+
Sbjct: 429 FDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAAC------EATGRQLLTKP 482
Query: 429 TTHGAR--ALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVT--- 483
R SC E + L G+ + C W E C CP PP + N + T
Sbjct: 483 QHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSS 542
Query: 484 VNGHKAGSLASYTCENG------HILSGSTSVTCTLG----GAWSGVPPSCKY----VNC 529
+ G+ +YTC G L G +++ CT G WSG P CK V C
Sbjct: 543 LEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQC 602
Query: 530 GTPTIHKGSFVLINGTTT---YGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELT 586
+H + I+G Y F C + L G+ ++ C D W +IP CE
Sbjct: 603 SH--VHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKG 660
Query: 587 SCPEPEVPSGGYMEAFDYYVHS--TINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYI 644
P + G + + S T+++ C+ G+ L+G ++ C G WS +P CE
Sbjct: 661 CQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRCEET 720
Query: 645 DCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTC--TEEFQWSDSSPRCE 702
C + EL G+ ++ SC Y+L G + C E W P C+
Sbjct: 721 -CQHVRQ---SLQELPAGSRV--ELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCK 774
Query: 703 EIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGE 762
I C P V V G HT + ++N GN V Y C++G+ ++GE
Sbjct: 775 VIHCHPPPVI------VNGK-----HTGMM-AENFLYGNE------VSYECDQGFYLLGE 816
Query: 763 SLSTCEDN----GQWSGTTPTC----QYVDCGNPGRIENGKVTLPSNATFYGATAFYQCD 814
C + G WSG +P C C NP K+ +A + + C+
Sbjct: 817 KKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCN 876
Query: 815 ENWELEGVIRRMCQENGTWSLEPPICKE---ITCPDPSAQIKAGSGLLVVTSTLSIGGEA 871
+ + G C + TW P C + I CP P + G+ + S G
Sbjct: 877 PGFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPP-KTPNGNHTGGNIARFSPGMSI 935
Query: 872 HYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIEN-GKIVISNGSTLFGSS 930
Y C++GY L G C +G W+ P C ++C SP +++ K + +G+
Sbjct: 936 LYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAV 995
Query: 931 VEYYCLSQYQRVGPFLRKCLDDGRWS 956
V C Y G +C D +W+
Sbjct: 996 VTLECEDGYMLEGSPQSQCQSDHQWN 1021
Score = 178 bits (433), Expect = 1e-43
Identities = 159/612 (25%), Positives = 239/612 (39%), Gaps = 81/612 (13%)
Query: 404 PSCKYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTC----GDEGIW 459
P ++CG PI +G ++ G YSC F L+G C +G W
Sbjct: 16 PGVLGISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTW 75
Query: 460 DGEAPRC----LFDWCPDPPAVSNASVT-VNGHKAGSLASYTCENGHILSGSTSVTCTLG 514
D AP+C + CP+P + ++ G ++ C+ ++G+ SV C
Sbjct: 76 DKPAPKCEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQAN 135
Query: 515 GAWSGVP-PSCKYV---NC-GTPTIHKGSFVLIN-GTTTYGSIAQFTCEPDYWLNGAEEL 568
W P+C V C P IH G N G+ G ++CE Y L G + +
Sbjct: 136 NMWGPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKII 195
Query: 569 VCNRDGKWSYDIPSCELTSCPE-PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLV 627
C GKWS P+CE C P+G E V T NF C+ G++L G P+
Sbjct: 196 NCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSR 255
Query: 628 CQQDGE---WSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHL--GSVIQYSCT------T 676
C G+ W+ P CE I C P + G + N ++ GS++ Y+C
Sbjct: 256 CVIAGQGVAWT-KMPVCEEIFCPSPPPILNG-RHIGNSLANVSYGSIVTYTCDPDPEEGV 313
Query: 677 NYRLVGPVRRTCTEEFQ----WSDSSPRCE----EIRCSDPIVAEKSIVSVTGNDRSHGH 728
N+ L+G CT + Q WS +PRCE ++C P + +VS + ++
Sbjct: 314 NFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYTYND 373
Query: 729 TLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNP 788
T+I + C G+ + G C G W + P C+ +C P
Sbjct: 374 TVI-------------------FACMFGFTLKGSKQIRCNAQGTWEPSAPVCE-KECQAP 413
Query: 789 GRIENGKVTLPSNATFYGATAF-YQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPD 847
I NG+ F T+ Y C+ + L G C G W+ P CK C
Sbjct: 414 PNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACE- 472
Query: 848 PSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDC 907
G LL + + + C GY L G + C W + +C I C
Sbjct: 473 -----ATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITC 527
Query: 908 RSPGNIENGKIVISNGSTL----FGSSVEYYCLS------QYQRVGPFLRKCLDD----G 953
P I NG GS+L +G++V Y C ++ +G +C + G
Sbjct: 528 PPPPVIYNG---AHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERG 584
Query: 954 RWSGEEPSCELA 965
WSG P C+L+
Sbjct: 585 TWSGPAPLCKLS 596
Score = 177 bits (431), Expect = 2e-43
Identities = 152/564 (26%), Positives = 221/564 (39%), Gaps = 71/564 (12%)
Query: 379 CPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDG-DVALIDNRTTHGARALY 437
C EG+ L G + C+ W CK + C I +G +G Y
Sbjct: 495 CGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTY 554
Query: 438 SCREN------FTLVGNPERTCG----DEGIWDGEAPRCLFDWCPDPPAVSNASVTV-NG 486
+C F+L+G C + G W G AP C AV + V + NG
Sbjct: 555 TCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLL----AVQCSHVHIANG 610
Query: 487 HK-AGSLASY--------TCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTIHKG 537
+K +G A Y C +G L GS+ + C W P C+ P +H G
Sbjct: 611 YKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKGCQSPPGLHHG 670
Query: 538 SFVLINGTTTY---GSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPE---- 590
G T + G +TC+P Y L G + + C G WS P CE T C
Sbjct: 671 RHT--GGNTVFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRCEET-CQHVRQS 727
Query: 591 -PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQ--QDGEWSGDSPTCEYIDCG 647
E+P+G +E +N C+ G++L G +CQ ++G W P C+ I C
Sbjct: 728 LQELPAGSRVEL--------VNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCH 779
Query: 648 KLPTLPYGTMELLNGTTHL-GSVIQYSCTTNYRLVGPVRRTCTEEFQ----WSDSSPRCE 702
P + G + L G+ + Y C + L+G + C + + WS SP+C
Sbjct: 780 PPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQC- 838
Query: 703 EIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGE 762
+R S P+ + HG+ L +T + Y +V C G+ + G
Sbjct: 839 -LR-SPPVTR------CPNPEVKHGYKLNKTH------SAYSHNDIVYVDCNPGFIMNGS 884
Query: 763 SLSTCEDNGQWSGTTPTC---QYVDCGNPGRIENGKVTLPSNATFY-GATAFYQCDENWE 818
+ C + W PTC ++ C P + NG T + A F G + Y CD+ +
Sbjct: 885 RVIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYL 944
Query: 819 LEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERG 878
L G +C GTWS P CKE+ C P+ GL G +CE G
Sbjct: 945 LVGEALLLCTHEGTWSQPAPHCKEVNCSSPADMDGIQKGL-EPRKMYQYGAVVTLECEDG 1003
Query: 879 YNLKGHQTRTCISKGQWNGTVPVC 902
Y L+G C S QWN + VC
Sbjct: 1004 YMLEGSPQSQCQSDHQWNPPLAVC 1027
Score = 167 bits (406), Expect = 2e-40
Identities = 138/483 (28%), Positives = 203/483 (42%), Gaps = 56/483 (11%)
Query: 520 VPPSCKYVNCGTPT-IHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVC----NRDG 574
V P ++CG+P I G + G++ +++C + L G + L+C DG
Sbjct: 14 VAPGVLGISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDG 73
Query: 575 KWSYDIPSCEL----TSCPEPEVPSGGYMEAFDYYVHS-TINFHCEAGHKLIGEPNLVCQ 629
W P CE +SCPEP VP G + Y H ++ F C+ + G ++ CQ
Sbjct: 74 TWDKPAPKCEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQ 133
Query: 630 QDGEWSGDS-PTCEYI---DCGKLPTLPYGTMELLN-GTTHLGSVIQYSCTTNYRLVGPV 684
+ W PTC + +C LP + G N G+ G + YSC + Y LVG
Sbjct: 134 ANNMWGPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEK 193
Query: 685 RRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYR 744
C +WS P CEE RC KS+ L R
Sbjct: 194 IINCLSSGKWSAVPPTCEEARC-------KSLGRFPNGKVKEPPIL-------------R 233
Query: 745 IGALVKYRCEKGYKVIGESLSTCEDNGQWSGTT--PTCQYVDCGNPGRIENGKVTLPSNA 802
+G + C++GY++ G S C GQ T P C+ + C +P I NG+ S A
Sbjct: 234 VGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTKMPVCEEIFCPSPPPILNGRHIGNSLA 293
Query: 803 TF-YGATAFYQCDE------NWELEGVIRRMC----QENGTWSLEPPICK----EITCPD 847
YG+ Y CD N+ L G C Q+ GTWS P C+ + CP
Sbjct: 294 NVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPH 353
Query: 848 PSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDC 907
P QI G + + + C G+ LKG + C ++G W + PVC +C
Sbjct: 354 P--QILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEK-EC 410
Query: 908 RSPGNIENGKIVISNGSTLF-GSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCELAT 966
++P NI NG+ + G+S++Y C Y VG +C +G W+ P C++A
Sbjct: 411 QAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAA 470
Query: 967 NEA 969
EA
Sbjct: 471 CEA 473
Score = 166 bits (403), Expect = 4e-40
Identities = 137/554 (24%), Positives = 222/554 (40%), Gaps = 63/554 (11%)
Query: 352 TCGSPDKLLNTTILGN---DYDVGSRIVYKCPEG------HMLLGDKSRHCKKD----GF 398
TC P + N G+ D+ G+ + Y C G L+G+ + C + G
Sbjct: 526 TCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGT 585
Query: 399 WSGAPPSCKY----VNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCG 454
WSG P CK V C + ++ + + + C FTL G+ + C
Sbjct: 586 WSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCK 645
Query: 455 DEGIWDGEAPRCLFDWCPDPPAVSNASVTVNG---HKAGSLASYTCENGHILSGSTSVTC 511
+ WD E P C C PP + + T +G YTC+ G++L G+ S+ C
Sbjct: 646 ADNTWDPEIPVCE-KGCQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIHC 704
Query: 512 TLGGAWSGVPPSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCN 571
G WS P C+ C + + L G+ + +C+ Y L G +C
Sbjct: 705 MPSGNWSPSAPRCEET-C--QHVRQSLQELPAGSRV--ELVNTSCQDGYQLTGHAYQMCQ 759
Query: 572 --RDGKWSYDIPSCELTSC-PEPEVPSGGY--MEAFDYYVHSTINFHCEAGHKLIGEPNL 626
+G W IP C++ C P P + +G + M A ++ + +++ C+ G L+GE L
Sbjct: 760 DAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKL 819
Query: 627 VCQQD----GEWSGDSPTC----EYIDCGKLPTLPYG-TMELLNGTTHLGSVIQYSCTTN 677
C+ D G WSG SP C C P + +G + + ++ C
Sbjct: 820 QCRSDSKGHGSWSGPSPQCLRSPPVTRCPN-PEVKHGYKLNKTHSAYSHNDIVYVDCNPG 878
Query: 678 YRLVGPVRRTCTEEFQWSDSSPRCEE---IRCSDPIVAEKSIVSVTGNDRSHGHTLIRTS 734
+ + G C + W P C + I C P T N G + R S
Sbjct: 879 FIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPP--------PKTPNGNHTGGNIARFS 930
Query: 735 DNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENG 794
G + Y C++GY ++GE+L C G WS P C+ V+C +P ++
Sbjct: 931 P----------GMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVNCSSPADMDGI 980
Query: 795 KVTL-PSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIK 853
+ L P YGA +C++ + LEG + CQ + W+ +C+ + I
Sbjct: 981 QKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSDHQWNPPLAVCRSRSLAPVLCGIA 1040
Query: 854 AGSGLLVVTSTLSI 867
AG LL +++
Sbjct: 1041 AGLILLTFLIVITL 1054
Score = 40.3 bits (90), Expect = 0.037
Identities = 23/75 (30%), Positives = 29/75 (38%), Gaps = 1/75 (1%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTN 61
C P PN + N G +Y CD+GY L G CT G W+ P C
Sbjct: 910 CPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHC-KE 968
Query: 62 VAFRKPANQSTTVRG 76
V PA+ +G
Sbjct: 969 VNCSSPADMDGIQKG 983
Score = 38.7 bits (86), Expect = 0.11
Identities = 19/56 (33%), Positives = 25/56 (44%), Gaps = 2/56 (3%)
Query: 5 PAVPP--NARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
PA+P N + N +I G Y C+ GY L G + C G W+ PP C
Sbjct: 155 PALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTC 210
Score = 36.3 bits (80), Expect = 0.60
Identities = 19/54 (35%), Positives = 24/54 (44%), Gaps = 3/54 (5%)
Query: 8 PPNARVSIPNEENIVA---GTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
PPN + ++V GT Y C+ GY L G +CT G WT P C
Sbjct: 413 PPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQC 466
Score = 36.3 bits (80), Expect = 0.60
Identities = 19/61 (31%), Positives = 28/61 (45%), Gaps = 4/61 (6%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTL----RGDWTLEPPF 57
C P V N + + EN + G YECD+G+ L G ++ +C G W+ P
Sbjct: 778 CHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQ 837
Query: 58 C 58
C
Sbjct: 838 C 838
Score = 34.7 bits (76), Expect = 1.8
Identities = 16/58 (27%), Positives = 26/58 (44%), Gaps = 1/58 (1%)
Query: 1 RCGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
+C HP + VS + T+ ++ C G+ L G++Q C +G W P C
Sbjct: 350 QCPHPQILRGRMVSGQKDRYTYNDTV-IFACMFGFTLKGSKQIRCNAQGTWEPSAPVC 406
Score = 34.7 bits (76), Expect = 1.8
Identities = 18/57 (31%), Positives = 24/57 (42%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C P + R + N V+G Y CD GY L G + C G+W+ P C
Sbjct: 661 CQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRC 717
>AK223627-1|BAD97347.1| 1092|Homo sapiens complement component
(3d/Epstein Barr virus) receptor 2 isoform 1 variant
protein.
Length = 1092
Score = 213 bits (521), Expect = 2e-54
Identities = 188/665 (28%), Positives = 274/665 (41%), Gaps = 81/665 (12%)
Query: 352 TCGSPDKLLNTTI--LGNDYDVGSRIVYKCPEGHMLLGDKSRHC----KKDGFWSGAPPS 405
+CGSP +LN I VG+ I Y C L+G+KS C K DG W P
Sbjct: 22 SCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPK 81
Query: 406 CKYVN--CGGLTPIEDGDVALIDNRT-THGARALYSCRENFTLVGNPERTCGDEGIWDG- 461
C+Y N PI G + + HG ++C+ NF++ GN C +W
Sbjct: 82 CEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWGPT 141
Query: 462 EAPRCLFDW---CPDPPAVSNA---SVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGG 515
P C+ + CP P + N S V G +Y+CE+G++L G + C G
Sbjct: 142 RLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSG 201
Query: 516 AWSGVPPSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGK 575
WS VPP+C+ C + V G A F C+ Y L G C G+
Sbjct: 202 KWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQ 261
Query: 576 ---WSYDIPSCELTSCPE-PEVPSGGYM--EAFDYYVHSTINFHCEAGHK------LIGE 623
W+ +P CE CP P + +G ++ + S + + C+ + LIGE
Sbjct: 262 GVAWT-KMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGE 320
Query: 624 PNLVC----QQDGEWSGDSPTCEY----IDCGKLPTLPYGTM--ELLNGTTHLGSVIQYS 673
L C Q+ G WSG +P CE + C P + G M + T+ +VI ++
Sbjct: 321 STLRCTVDSQKTGTWSGPAPRCELSTSAVQCPH-PQILRGRMVSGQKDRYTYNDTVI-FA 378
Query: 674 CTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRT 733
C + L G + C + W S+P CE+ C P +I++ DR ++R
Sbjct: 379 CMFGFTLKGSKQIRCNAQGTWEPSAPVCEK-ECQAP----PNILNGQKEDRH----MVR- 428
Query: 734 SDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIEN 793
+ G +KY C GY ++GE C G W+ P C+ C GR
Sbjct: 429 ---------FDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGR--- 476
Query: 794 GKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIK 853
+T P + F C E ++L G + + CQ W +E +CKEITCP P I
Sbjct: 477 QLLTKPQH-QFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPV-IY 534
Query: 854 AGSGLLVVTSTLSIGGEAHYQC----ERG--YNLKGHQTRTCIS----KGQWNGTVPVC- 902
G+ G Y C ERG ++L G T C S +G W+G P+C
Sbjct: 535 NGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCK 594
Query: 903 ---IPIDCRSPGNIENG-KIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGE 958
+ + C S +I NG KI + +V + C S + G +C D W E
Sbjct: 595 LSLLAVQC-SHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPE 653
Query: 959 EPSCE 963
P CE
Sbjct: 654 IPVCE 658
Score = 205 bits (500), Expect = 8e-52
Identities = 175/636 (27%), Positives = 257/636 (40%), Gaps = 79/636 (12%)
Query: 372 GSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRTTH 431
G + Y C G++L+G+K +C G WS PP+C+ C L +G V
Sbjct: 176 GLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRV- 234
Query: 432 GARALYSCRENFTLVGNPERTC--GDEGIWDGEAPRCLFDWCPDPPAVSNASVTVN---G 486
G A + C E + L G P C +G+ + P C +CP PP + N N
Sbjct: 235 GVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTKMPVCEEIFCPSPPPILNGRHIGNSLAN 294
Query: 487 HKAGSLASYTC----ENG--HILSGSTSVTCTLG----GAWSGVPPSCKY----VNCGTP 532
GS+ +YTC E G IL G +++ CT+ G WSG P C+ V C P
Sbjct: 295 VSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHP 354
Query: 533 TIHKGSFVL-INGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEP 591
I +G V TY F C + L G++++ CN G W P CE P
Sbjct: 355 QILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKECQAPP 414
Query: 592 EVPSG----GYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCG 647
+ +G +M FD ++I + C G+ L+GE ++ C +G W+ P C+ C
Sbjct: 415 NILNGQKEDRHMVRFD--PGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACE 472
Query: 648 KLPTLPYGTMELLNGTTH--LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIR 705
+LL H + + SC Y+L G V + C W C+EI
Sbjct: 473 AT------GRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEIT 526
Query: 706 CSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKG------YKV 759
C P V N G +L + G V Y C G + +
Sbjct: 527 CPPP--------PVIYNGAHTGSSL----------EDFPYGTTVTYTCNPGPERGVEFSL 568
Query: 760 IGESLSTCEDN----GQWSGTTPTCQY----VDCGNPGRIENG-KVTLPSNATFYGATAF 810
IGES C N G WSG P C+ V C + I NG K++ FY T
Sbjct: 569 IGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHV-HIANGYKISGKEAPYFYNDTVT 627
Query: 811 YQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGE 870
++C + L+G + C+ + TW E P+C E C P + G T G
Sbjct: 628 FKCYSGFTLKGSSQIRCKADNTWDPEIPVC-EKGCQSPPG-LHHGRHTGGNTVFFVSGMT 685
Query: 871 AHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSS 930
Y C+ GY L G+++ C+ G W+ + P C C+ ++ + GS +
Sbjct: 686 VDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRC-EETCQ---HVRQSLQELPAGSRV--EL 739
Query: 931 VEYYCLSQYQRVGPFLRKCLD--DGRWSGEEPSCEL 964
V C YQ G + C D +G W + P C++
Sbjct: 740 VNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKV 775
Score = 202 bits (494), Expect = 4e-51
Identities = 176/651 (27%), Positives = 254/651 (39%), Gaps = 74/651 (11%)
Query: 353 CGSPDKLLNTTILGND--YDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVN 410
C P L + G Y +++ C G L G K C G W + P C+
Sbjct: 351 CPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEK-E 409
Query: 411 CGGLTPIEDG---DVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL 467
C I +G D ++ R G YSC + LVG C EG+W P+C
Sbjct: 410 CQAPPNILNGQKEDRHMV--RFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCK 467
Query: 468 FDWCPDPPAVSNASVTVNGHK-AGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKY 526
C A +T H+ + +C G+ LSGS C W CK
Sbjct: 468 VAACE---ATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKE 524
Query: 527 VNCGTP-TIHKGSFVLIN-GTTTYGSIAQFTCEP------DYWLNGAEELVCNRD----G 574
+ C P I+ G+ + YG+ +TC P ++ L G + C + G
Sbjct: 525 ITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERG 584
Query: 575 KWSYDIPSCELT----SCPEPEVPSGGYMEAFD--YYVHSTINFHCEAGHKLIGEPNLVC 628
WS P C+L+ C + +G + + Y+ + T+ F C +G L G + C
Sbjct: 585 TWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRC 644
Query: 629 QQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHL-GSVIQYSCTTNYRLVGPVRRT 687
+ D W + P CE C P L +G N + G + Y+C Y LVG
Sbjct: 645 KADNTWDPEIPVCEK-GCQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIH 703
Query: 688 CTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGA 747
C WS S+PRCEE C +S+ + R L+ TS
Sbjct: 704 CMPSGNWSPSAPRCEET-CQH---VRQSLQELPAGSRVE---LVNTS------------- 743
Query: 748 LVKYRCEKGYKVIGESLSTCED--NGQWSGTTPTCQYVDCGNPGRIENGKVT-LPSNATF 804
C+ GY++ G + C+D NG W P C+ + C P I NGK T + +
Sbjct: 744 -----CQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFL 798
Query: 805 YGATAFYQCDENWELEGVIRRMCQEN----GTWSLEPPICKE---IT-CPDPSAQIKAGS 856
YG Y+CD+ + L G + C+ + G+WS P C +T CP+P ++K G
Sbjct: 799 YGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNP--EVKHGY 856
Query: 857 GLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIP---IDCRSPGNI 913
L S S + C G+ + G + C + W VP CI I C P
Sbjct: 857 KLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPPKT 916
Query: 914 ENGKIVISNGSTLF-GSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
NG N + G S+ Y C Y VG L C +G WS P C+
Sbjct: 917 PNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCK 967
Score = 188 bits (458), Expect = 9e-47
Identities = 162/626 (25%), Positives = 247/626 (39%), Gaps = 71/626 (11%)
Query: 369 YDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNR 428
+D G+ I Y C G++L+G++S C +G W+ P CK C E L+
Sbjct: 429 FDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAAC------EATGRQLLTKP 482
Query: 429 TTHGAR--ALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVT--- 483
R SC E + L G+ + C W E C CP PP + N + T
Sbjct: 483 QHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSS 542
Query: 484 VNGHKAGSLASYTCENG------HILSGSTSVTCTLG----GAWSGVPPSCKY----VNC 529
+ G+ +YTC G L G +++ CT G WSG P CK V C
Sbjct: 543 LEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQC 602
Query: 530 GTPTIHKGSFVLINGTTT---YGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELT 586
+H + I+G Y F C + L G+ ++ C D W +IP CE
Sbjct: 603 SH--VHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKG 660
Query: 587 SCPEPEVPSGGYMEAFDYYVHS--TINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYI 644
P + G + + S T+++ C+ G+ L+G ++ C G WS +P CE
Sbjct: 661 CQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRCEET 720
Query: 645 DCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTC--TEEFQWSDSSPRCE 702
C + EL G+ ++ SC Y+L G + C E W P C+
Sbjct: 721 -CQHVRQ---SLQELPAGSRV--ELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCK 774
Query: 703 EIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGE 762
I C P V V G HT + ++N GN V Y C++G+ ++GE
Sbjct: 775 VIHCHPPPVI------VNGK-----HTGMM-AENFLYGNE------VSYECDQGFYLLGE 816
Query: 763 SLSTCEDN----GQWSGTTPTC----QYVDCGNPGRIENGKVTLPSNATFYGATAFYQCD 814
C + G WSG +P C C NP K+ +A + + C+
Sbjct: 817 KKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCN 876
Query: 815 ENWELEGVIRRMCQENGTWSLEPPICKE---ITCPDPSAQIKAGSGLLVVTSTLSIGGEA 871
+ + G C + TW P C + I CP P + G+ + S G
Sbjct: 877 PGFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPP-KTPNGNHTGGNIARFSPGMSI 935
Query: 872 HYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIEN-GKIVISNGSTLFGSS 930
Y C++GY L G C +G W+ P C ++C SP +++ K + +G+
Sbjct: 936 LYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAV 995
Query: 931 VEYYCLSQYQRVGPFLRKCLDDGRWS 956
V C Y G +C D +W+
Sbjct: 996 VTLECEDGYMLEGSPQSQCQSDHQWN 1021
Score = 178 bits (433), Expect = 1e-43
Identities = 159/612 (25%), Positives = 239/612 (39%), Gaps = 81/612 (13%)
Query: 404 PSCKYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTC----GDEGIW 459
P ++CG PI +G ++ G YSC F L+G C +G W
Sbjct: 16 PGVLGISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTW 75
Query: 460 DGEAPRC----LFDWCPDPPAVSNASVT-VNGHKAGSLASYTCENGHILSGSTSVTCTLG 514
D AP+C + CP+P + ++ G ++ C+ ++G+ SV C
Sbjct: 76 DKPAPKCEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQAN 135
Query: 515 GAWSGVP-PSCKYV---NC-GTPTIHKGSFVLIN-GTTTYGSIAQFTCEPDYWLNGAEEL 568
W P+C V C P IH G N G+ G ++CE Y L G + +
Sbjct: 136 NMWGPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKII 195
Query: 569 VCNRDGKWSYDIPSCELTSCPE-PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLV 627
C GKWS P+CE C P+G E V T NF C+ G++L G P+
Sbjct: 196 NCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSR 255
Query: 628 CQQDGE---WSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHL--GSVIQYSCT------T 676
C G+ W+ P CE I C P + G + N ++ GS++ Y+C
Sbjct: 256 CVIAGQGVAWT-KMPVCEEIFCPSPPPILNG-RHIGNSLANVSYGSIVTYTCDPDPEEGV 313
Query: 677 NYRLVGPVRRTCTEEFQ----WSDSSPRCE----EIRCSDPIVAEKSIVSVTGNDRSHGH 728
N+ L+G CT + Q WS +PRCE ++C P + +VS + ++
Sbjct: 314 NFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYTYND 373
Query: 729 TLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNP 788
T+I + C G+ + G C G W + P C+ +C P
Sbjct: 374 TVI-------------------FACMFGFTLKGSKQIRCNAQGTWEPSAPVCE-KECQAP 413
Query: 789 GRIENGKVTLPSNATFYGATAF-YQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPD 847
I NG+ F T+ Y C+ + L G C G W+ P CK C
Sbjct: 414 PNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACE- 472
Query: 848 PSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDC 907
G LL + + + C GY L G + C W + +C I C
Sbjct: 473 -----ATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITC 527
Query: 908 RSPGNIENGKIVISNGSTL----FGSSVEYYCLS------QYQRVGPFLRKCLDD----G 953
P I NG GS+L +G++V Y C ++ +G +C + G
Sbjct: 528 PPPPVIYNG---AHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERG 584
Query: 954 RWSGEEPSCELA 965
WSG P C+L+
Sbjct: 585 TWSGPAPLCKLS 596
Score = 177 bits (431), Expect = 2e-43
Identities = 152/564 (26%), Positives = 221/564 (39%), Gaps = 71/564 (12%)
Query: 379 CPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDG-DVALIDNRTTHGARALY 437
C EG+ L G + C+ W CK + C I +G +G Y
Sbjct: 495 CGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTY 554
Query: 438 SCREN------FTLVGNPERTCG----DEGIWDGEAPRCLFDWCPDPPAVSNASVTV-NG 486
+C F+L+G C + G W G AP C AV + V + NG
Sbjct: 555 TCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLL----AVQCSHVHIANG 610
Query: 487 HK-AGSLASY--------TCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTIHKG 537
+K +G A Y C +G L GS+ + C W P C+ P +H G
Sbjct: 611 YKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKGCQSPPGLHHG 670
Query: 538 SFVLINGTTTY---GSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPE---- 590
G T + G +TC+P Y L G + + C G WS P CE T C
Sbjct: 671 RHT--GGNTVFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRCEET-CQHVRQS 727
Query: 591 -PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQ--QDGEWSGDSPTCEYIDCG 647
E+P+G +E +N C+ G++L G +CQ ++G W P C+ I C
Sbjct: 728 LQELPAGSRVEL--------VNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCH 779
Query: 648 KLPTLPYGTMELLNGTTHL-GSVIQYSCTTNYRLVGPVRRTCTEEFQ----WSDSSPRCE 702
P + G + L G+ + Y C + L+G + C + + WS SP+C
Sbjct: 780 PPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQC- 838
Query: 703 EIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGE 762
+R S P+ + HG+ L +T + Y +V C G+ + G
Sbjct: 839 -LR-SPPVTR------CPNPEVKHGYKLNKTH------SAYSHNDIVYVDCNPGFIMNGS 884
Query: 763 SLSTCEDNGQWSGTTPTC---QYVDCGNPGRIENGKVTLPSNATFY-GATAFYQCDENWE 818
+ C + W PTC ++ C P + NG T + A F G + Y CD+ +
Sbjct: 885 RVIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYL 944
Query: 819 LEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERG 878
L G +C GTWS P CKE+ C P+ GL G +CE G
Sbjct: 945 LVGEALLLCTHEGTWSQPAPHCKEVNCSSPADMDGIQKGL-EPRKMYQYGAVVTLECEDG 1003
Query: 879 YNLKGHQTRTCISKGQWNGTVPVC 902
Y L+G C S QWN + VC
Sbjct: 1004 YMLEGSPQSQCQSDHQWNPPLAVC 1027
Score = 167 bits (406), Expect = 2e-40
Identities = 138/483 (28%), Positives = 203/483 (42%), Gaps = 56/483 (11%)
Query: 520 VPPSCKYVNCGTPT-IHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVC----NRDG 574
V P ++CG+P I G + G++ +++C + L G + L+C DG
Sbjct: 14 VAPGVLGISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDG 73
Query: 575 KWSYDIPSCEL----TSCPEPEVPSGGYMEAFDYYVHS-TINFHCEAGHKLIGEPNLVCQ 629
W P CE +SCPEP VP G + Y H ++ F C+ + G ++ CQ
Sbjct: 74 TWDKPAPKCEYFNKYSSCPEPIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQ 133
Query: 630 QDGEWSGDS-PTCEYI---DCGKLPTLPYGTMELLN-GTTHLGSVIQYSCTTNYRLVGPV 684
+ W PTC + +C LP + G N G+ G + YSC + Y LVG
Sbjct: 134 ANNMWGPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEK 193
Query: 685 RRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYR 744
C +WS P CEE RC KS+ L R
Sbjct: 194 IINCLSSGKWSAVPPTCEEARC-------KSLGRFPNGKVKEPPIL-------------R 233
Query: 745 IGALVKYRCEKGYKVIGESLSTCEDNGQWSGTT--PTCQYVDCGNPGRIENGKVTLPSNA 802
+G + C++GY++ G S C GQ T P C+ + C +P I NG+ S A
Sbjct: 234 VGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTKMPVCEEIFCPSPPPILNGRHIGNSLA 293
Query: 803 TF-YGATAFYQCDE------NWELEGVIRRMC----QENGTWSLEPPICK----EITCPD 847
YG+ Y CD N+ L G C Q+ GTWS P C+ + CP
Sbjct: 294 NVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPH 353
Query: 848 PSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDC 907
P QI G + + + C G+ LKG + C ++G W + PVC +C
Sbjct: 354 P--QILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEK-EC 410
Query: 908 RSPGNIENGKIVISNGSTLF-GSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCELAT 966
++P NI NG+ + G+S++Y C Y VG +C +G W+ P C++A
Sbjct: 411 QAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAA 470
Query: 967 NEA 969
EA
Sbjct: 471 CEA 473
Score = 166 bits (403), Expect = 4e-40
Identities = 137/554 (24%), Positives = 222/554 (40%), Gaps = 63/554 (11%)
Query: 352 TCGSPDKLLNTTILGN---DYDVGSRIVYKCPEG------HMLLGDKSRHCKKD----GF 398
TC P + N G+ D+ G+ + Y C G L+G+ + C + G
Sbjct: 526 TCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGT 585
Query: 399 WSGAPPSCKY----VNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCG 454
WSG P CK V C + ++ + + + C FTL G+ + C
Sbjct: 586 WSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCK 645
Query: 455 DEGIWDGEAPRCLFDWCPDPPAVSNASVTVNG---HKAGSLASYTCENGHILSGSTSVTC 511
+ WD E P C C PP + + T +G YTC+ G++L G+ S+ C
Sbjct: 646 ADNTWDPEIPVCE-KGCQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIHC 704
Query: 512 TLGGAWSGVPPSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCN 571
G WS P C+ C + + L G+ + +C+ Y L G +C
Sbjct: 705 MPSGNWSPSAPRCEET-C--QHVRQSLQELPAGSRV--ELVNTSCQDGYQLTGHAYQMCQ 759
Query: 572 --RDGKWSYDIPSCELTSC-PEPEVPSGGY--MEAFDYYVHSTINFHCEAGHKLIGEPNL 626
+G W IP C++ C P P + +G + M A ++ + +++ C+ G L+GE L
Sbjct: 760 DAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKL 819
Query: 627 VCQQD----GEWSGDSPTC----EYIDCGKLPTLPYG-TMELLNGTTHLGSVIQYSCTTN 677
C+ D G WSG SP C C P + +G + + ++ C
Sbjct: 820 QCRSDSKGHGSWSGPSPQCLRSPPVTRCPN-PEVKHGYKLNKTHSAYSHNDIVYVDCNPG 878
Query: 678 YRLVGPVRRTCTEEFQWSDSSPRCEE---IRCSDPIVAEKSIVSVTGNDRSHGHTLIRTS 734
+ + G C + W P C + I C P T N G + R S
Sbjct: 879 FIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPP--------PKTPNGNHTGGNIARFS 930
Query: 735 DNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENG 794
G + Y C++GY ++GE+L C G WS P C+ V+C +P ++
Sbjct: 931 P----------GMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVNCSSPADMDGI 980
Query: 795 KVTL-PSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIK 853
+ L P YGA +C++ + LEG + CQ + W+ +C+ + I
Sbjct: 981 QKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSDHQWNPPLAVCRSRSLAPVLCGIA 1040
Query: 854 AGSGLLVVTSTLSI 867
AG LL +++
Sbjct: 1041 AGLILLTFLIVITL 1054
Score = 40.3 bits (90), Expect = 0.037
Identities = 23/75 (30%), Positives = 29/75 (38%), Gaps = 1/75 (1%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTN 61
C P PN + N G +Y CD+GY L G CT G W+ P C
Sbjct: 910 CPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHC-KE 968
Query: 62 VAFRKPANQSTTVRG 76
V PA+ +G
Sbjct: 969 VNCSSPADMDGIQKG 983
Score = 38.7 bits (86), Expect = 0.11
Identities = 19/56 (33%), Positives = 25/56 (44%), Gaps = 2/56 (3%)
Query: 5 PAVPP--NARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
PA+P N + N +I G Y C+ GY L G + C G W+ PP C
Sbjct: 155 PALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTC 210
Score = 36.3 bits (80), Expect = 0.60
Identities = 19/54 (35%), Positives = 24/54 (44%), Gaps = 3/54 (5%)
Query: 8 PPNARVSIPNEENIVA---GTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
PPN + ++V GT Y C+ GY L G +CT G WT P C
Sbjct: 413 PPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQC 466
Score = 36.3 bits (80), Expect = 0.60
Identities = 19/61 (31%), Positives = 28/61 (45%), Gaps = 4/61 (6%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTL----RGDWTLEPPF 57
C P V N + + EN + G YECD+G+ L G ++ +C G W+ P
Sbjct: 778 CHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQ 837
Query: 58 C 58
C
Sbjct: 838 C 838
Score = 34.7 bits (76), Expect = 1.8
Identities = 16/58 (27%), Positives = 26/58 (44%), Gaps = 1/58 (1%)
Query: 1 RCGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
+C HP + VS + T+ ++ C G+ L G++Q C +G W P C
Sbjct: 350 QCPHPQILRGRMVSGQKDRYTYNDTV-IFACMFGFTLKGSKQIRCNAQGTWEPSAPVC 406
Score = 34.7 bits (76), Expect = 1.8
Identities = 18/57 (31%), Positives = 24/57 (42%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C P + R + N V+G Y CD GY L G + C G+W+ P C
Sbjct: 661 CQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRC 717
>Z99572-4|CAI23057.1| 768|Homo sapiens selectin P (granule membrane
protein 140kDa, antigen CD62) protein.
Length = 768
Score = 206 bits (504), Expect = 3e-52
Identities = 135/462 (29%), Positives = 205/462 (44%), Gaps = 49/462 (10%)
Query: 346 CQYLP-PTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPP 404
CQ+L P+ G+ D + T + GS ++C G+ + G C G WS P
Sbjct: 262 CQHLEAPSEGTMDCVHPLTA----FAYGSSCKFECQPGYRVRGLDMLRCIDSGHWSAPLP 317
Query: 405 SCKYVNCGGL-TPIEDG-DVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGE 462
+C+ ++C L +P+ D + + + C E F L G C + G W
Sbjct: 318 TCEAISCEPLESPVHGSMDCSPSLRAFQYDTNCSFRCAEGFMLRGADIVRCDNLGQWTAP 377
Query: 463 APRCLFDWCPDPPAVSNASVTVNGHKAG-----SLASYTCENGHILSGSTSVTCTLGGAW 517
AP C C D P + A V + H G S+ S+TC G +L G++ + C G W
Sbjct: 378 APVCQALQCQDLPVPNEARVNCS-HPFGAFRYQSVCSFTCNEGLLLVGASVLQCLATGNW 436
Query: 518 SGVPPSCKYVNCGTPTI--HKGSFVLIN--GTTTYGSIAQFTCEPDYWLNGAEELVCNRD 573
+ VPP C+ + C TP + G+ + G+++Y S QF C+ Y L+G E L C R
Sbjct: 437 NSVPPECQAIPC-TPLLSPQNGTMTCVQPLGSSSYKSTCQFICDEGYSLSGPERLDCTRS 495
Query: 574 GKWSYDIPSCELTSCPEPEVPSGGYMEAFD----YYVHSTINFHCEAGHKLIGEPNLVCQ 629
G+W+ P CE CPE P G ++ D + V ST +F C+ G KL G N+ C
Sbjct: 496 GRWTDSPPMCEAIKCPELFAPEQGSLDCSDTRGEFNVGSTCHFSCDNGFKLEGPNNVECT 555
Query: 630 QDGEWSGDSPTCEYI--------DCGKLPTLPYGTMELLN--GTTHLGSVIQYSCTTNYR 679
G WS PTC+ I C L T GTM + GT + + C +
Sbjct: 556 TSGRWSATPPTCKGIASLPTPGVQCPALTTPGQGTMYCRHHPGTFGFNTTCYFGCNAGFT 615
Query: 680 LVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDV 739
L+G +C QW+ +P C ++CS+ + K I N +
Sbjct: 616 LIGDSTLSCRPSGQWTAVTPACRAVKCSE-LHVNKPIAMNCSN----------------L 658
Query: 740 GNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQ 781
+ G++ + C +G + G + + C++NG WS T PTCQ
Sbjct: 659 WGNFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTCQ 700
Score = 206 bits (502), Expect = 4e-52
Identities = 172/703 (24%), Positives = 279/703 (39%), Gaps = 91/703 (12%)
Query: 236 SFDEARKQCQSHGGDLIHGFQGATSSFLTQELERRKAQLKTQLVWIGAQKEPGLTSRTWQ 295
S++ +RK CQ+ DL+ +L + L + WIG +K ++TW
Sbjct: 52 SWNISRKYCQNRYTDLVAIQNKNEIDYLNKVLP-----YYSSYYWIGIRKN----NKTWT 102
Query: 296 WVDGELV---SKPSWGKDQPNNYNGEQNCV---VLDGGRGWLWNDVGCNLDYLHWICQYL 349
WV + +W ++PNN ++CV + WND C L H +C
Sbjct: 103 WVGTKKALTNEAENWADNEPNNKRNNEDCVEIYIKSPSAPGKWNDEHC-LKKKHALCY-- 159
Query: 350 PPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYV 409
T D ++ + G +C E +G+ + C GF+ P C+YV
Sbjct: 160 --TASCQD--MSCSKQG-----------ECLE---TIGNYTCSCYP-GFYG---PECEYV 197
Query: 410 N-CGGLTPIEDGDVALID--NRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRC 466
CG L + + + ++ + C + + + G + C GIW + P+C
Sbjct: 198 RECGELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQC 257
Query: 467 LFDWCPDPPAVSNASVT----VNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPP 522
L C A S ++ + GS + C+ G+ + G + C G WS P
Sbjct: 258 LAVQCQHLEAPSEGTMDCVHPLTAFAYGSSCKFECQPGYRVRGLDMLRCIDSGHWSAPLP 317
Query: 523 SCKYVNCGT--PTIHKGSFVLINGTTT--YGSIAQFTCEPDYWLNGAEELVCNRDGKWSY 578
+C+ ++C +H GS Y + F C + L GA+ + C+ G+W+
Sbjct: 318 TCEAISCEPLESPVH-GSMDCSPSLRAFQYDTNCSFRCAEGFMLRGADIVRCDNLGQWTA 376
Query: 579 DIPSCELTSCPEPEVPSGGYME------AFDYYVHSTINFHCEAGHKLIGEPNLVCQQDG 632
P C+ C + VP+ + AF Y S +F C G L+G L C G
Sbjct: 377 PAPVCQALQCQDLPVPNEARVNCSHPFGAFRY--QSVCSFTCNEGLLLVGASVLQCLATG 434
Query: 633 EWSGDSPTCEYIDCGKLPTLPYGTMELLN--GTTHLGSVIQYSCTTNYRLVGPVRRTCTE 690
W+ P C+ I C L + GTM + G++ S Q+ C Y L GP R CT
Sbjct: 435 NWNSVPPECQAIPCTPLLSPQNGTMTCVQPLGSSSYKSTCQFICDEGYSLSGPERLDCTR 494
Query: 691 EFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVK 750
+W+DS P CE I+C + E+ + D D + +G+
Sbjct: 495 SGRWTDSPPMCEAIKCPELFAPEQG-----------------SLDCSDTRGEFNVGSTCH 537
Query: 751 YRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYV-DCGNPGRIENGKVTLPSNATFY---- 805
+ C+ G+K+ G + C +G+WS T PTC+ + PG ++ +T P T Y
Sbjct: 538 FSCDNGFKLEGPNNVECTTSGRWSATPPTCKGIASLPTPG-VQCPALTTPGQGTMYCRHH 596
Query: 806 ------GATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLL 859
T ++ C+ + L G C+ +G W+ P C+ + C +
Sbjct: 597 PGTFGFNTTCYFGCNAGFTLIGDSTLSCRPSGQWTAVTPACRAVKCSELHVNKPIAMNCS 656
Query: 860 VVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVC 902
+ S G + C G L G C G W+ TVP C
Sbjct: 657 NLWGNFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTC 699
Score = 202 bits (493), Expect = 5e-51
Identities = 132/508 (25%), Positives = 211/508 (41%), Gaps = 42/508 (8%)
Query: 479 NASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCG-TPTIHKG 537
N S + S S+ C +G+ ++G + + C G W+ PP C V C +G
Sbjct: 212 NCSHPLGNFSFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQCLAVQCQHLEAPSEG 271
Query: 538 SFVLINGTTT--YGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPS 595
+ ++ T YGS +F C+P Y + G + L C G WS +P+CE SC E P
Sbjct: 272 TMDCVHPLTAFAYGSSCKFECQPGYRVRGLDMLRCIDSGHWSAPLPTCEAISCEPLESPV 331
Query: 596 GGYME------AFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKL 649
G M+ AF Y + +F C G L G + C G+W+ +P C+ + C L
Sbjct: 332 HGSMDCSPSLRAFQY--DTNCSFRCAEGFMLRGADIVRCDNLGQWTAPAPVCQALQCQDL 389
Query: 650 PTLPYGTMELLN--GTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCS 707
P + + G SV ++C LVG C W+ P C+ I C+
Sbjct: 390 PVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPECQAIPCT 449
Query: 708 DPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTC 767
P+++ ++ T ++ + +T ++ C++GY + G C
Sbjct: 450 -PLLSPQNGTM----------TCVQPLGSSSYKST------CQFICDEGYSLSGPERLDC 492
Query: 768 EDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFY--GATAFYQCDENWELEGVIRR 825
+G+W+ + P C+ + C E G + + G+T + CD ++LEG
Sbjct: 493 TRSGRWTDSPPMCEAIKCPELFAPEQGSLDCSDTRGEFNVGSTCHFSCDNGFKLEGPNNV 552
Query: 826 MCQENGTWSLEPPICKEI-TCPDPSAQIKA----GSGLLVVT---STLSIGGEAHYQCER 877
C +G WS PP CK I + P P Q A G G + T ++ C
Sbjct: 553 ECTTSGRWSATPPTCKGIASLPTPGVQCPALTTPGQGTMYCRHHPGTFGFNTTCYFGCNA 612
Query: 878 GYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISN--GSTLFGSSVEYYC 935
G+ L G T +C GQW P C + C + + SN G+ +GS ++C
Sbjct: 613 GFTLIGDSTLSCRPSGQWTAVTPACRAVKCSELHVNKPIAMNCSNLWGNFSYGSICSFHC 672
Query: 936 LSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
L G C ++G WS P+C+
Sbjct: 673 LEGQLLNGSAQTACQENGHWSTTVPTCQ 700
Score = 189 bits (460), Expect = 5e-47
Identities = 125/489 (25%), Positives = 203/489 (41%), Gaps = 45/489 (9%)
Query: 498 ENGHILSGSTSVTCTLGGAWSGVPPSCKYVN-CGTPTIHKGSFVLIN-----GTTTYGSI 551
+ G L + TC+ + G P C+YV CG + VL+N G ++ S
Sbjct: 170 KQGECLETIGNYTCSCYPGFYG--PECEYVRECGE--LELPQHVLMNCSHPLGNFSFNSQ 225
Query: 552 AQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFD----YYVH 607
F C Y +NG +L C G W+ P C C E PS G M+ +
Sbjct: 226 CSFHCTDGYQVNGPSKLECLASGIWTNKPPQCLAVQCQHLEAPSEGTMDCVHPLTAFAYG 285
Query: 608 STINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTT--H 665
S+ F C+ G+++ G L C G WS PTCE I C L + +G+M+
Sbjct: 286 SSCKFECQPGYRVRGLDMLRCIDSGHWSAPLPTCEAISCEPLESPVHGSMDCSPSLRAFQ 345
Query: 666 LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRS 725
+ + C + L G C QW+ +P C+ ++C D V ++ V+ S
Sbjct: 346 YDTNCSFRCAEGFMLRGADIVRCDNLGQWTAPAPVCQALQCQDLPVPNEARVNC-----S 400
Query: 726 HGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDC 785
H +R ++ + C +G ++G S+ C G W+ P CQ + C
Sbjct: 401 HPF------------GAFRYQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPECQAIPC 448
Query: 786 GNPGRIENGKVTL--PSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEI 843
+NG +T P ++ Y +T + CDE + L G R C +G W+ PP+C+ I
Sbjct: 449 TPLLSPQNGTMTCVQPLGSSSYKSTCQFICDEGYSLSGPERLDCTRSGRWTDSPPMCEAI 508
Query: 844 TCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVC- 902
CP+ A + ++G H+ C+ G+ L+G C + G+W+ T P C
Sbjct: 509 KCPELFAPEQGSLDCSDTRGEFNVGSTCHFSCDNGFKLEGPNNVECTTSGRWSATPPTCK 568
Query: 903 ----IP---IDCRSPGNIENGKIVISNGSTLFGSSVEYY--CLSQYQRVGPFLRKCLDDG 953
+P + C + G + + FG + Y C + + +G C G
Sbjct: 569 GIASLPTPGVQCPALTTPGQGTMYCRHHPGTFGFNTTCYFGCNAGFTLIGDSTLSCRPSG 628
Query: 954 RWSGEEPSC 962
+W+ P+C
Sbjct: 629 QWTAVTPAC 637
Score = 132 bits (318), Expect = 9e-30
Identities = 83/332 (25%), Positives = 130/332 (39%), Gaps = 24/332 (7%)
Query: 639 PTCEYI-DCGKLPTLPYGTMELLN--GTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWS 695
P CEY+ +CG+L + M + G S + CT Y++ GP + C W+
Sbjct: 192 PECEYVRECGELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPSKLECLASGIWT 251
Query: 696 DSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEK 755
+ P+C ++C + + H L + G+ K+ C+
Sbjct: 252 NKPPQCLAVQCQHLEAPSEGTMDCV-------HPL----------TAFAYGSSCKFECQP 294
Query: 756 GYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTL-PSNATF-YGATAFYQC 813
GY+V G + C D+G WS PTC+ + C +G + PS F Y ++C
Sbjct: 295 GYRVRGLDMLRCIDSGHWSAPLPTCEAISCEPLESPVHGSMDCSPSLRAFQYDTNCSFRC 354
Query: 814 DENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHY 873
E + L G C G W+ P+C+ + C D +A +
Sbjct: 355 AEGFMLRGADIVRCDNLGQWTAPAPVCQALQCQDLPVPNEARVNCSHPFGAFRYQSVCSF 414
Query: 874 QCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISN--GSTLFGSSV 931
C G L G C++ G WN P C I C + +NG + GS+ + S+
Sbjct: 415 TCNEGLLLVGASVLQCLATGNWNSVPPECQAIPCTPLLSPQNGTMTCVQPLGSSSYKSTC 474
Query: 932 EYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
++ C Y GP C GRW+ P CE
Sbjct: 475 QFICDEGYSLSGPERLDCTRSGRWTDSPPMCE 506
Score = 63.7 bits (148), Expect = 3e-09
Identities = 30/109 (27%), Positives = 50/109 (45%), Gaps = 2/109 (1%)
Query: 866 SIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGST 925
S + + C GY + G C++ G W P C+ + C+ G + + T
Sbjct: 221 SFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQCLAVQCQHLEAPSEGTMDCVHPLT 280
Query: 926 LF--GSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCELATNEAVDS 972
F GSS ++ C Y+ G + +C+D G WS P+CE + E ++S
Sbjct: 281 AFAYGSSCKFECQPGYRVRGLDMLRCIDSGHWSAPLPTCEAISCEPLES 329
Score = 40.7 bits (91), Expect = 0.028
Identities = 15/28 (53%), Positives = 17/28 (60%)
Query: 31 CDEGYELFGARQRECTLRGDWTLEPPFC 58
CDEGY L G + +CT G WT PP C
Sbjct: 478 CDEGYSLSGPERLDCTRSGRWTDSPPMC 505
Score = 38.7 bits (86), Expect = 0.11
Identities = 14/35 (40%), Positives = 19/35 (54%)
Query: 24 GTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
G+ + CD G++L G ECT G W+ PP C
Sbjct: 533 GSTCHFSCDNGFKLEGPNNVECTTSGRWSATPPTC 567
Score = 35.9 bits (79), Expect = 0.79
Identities = 16/58 (27%), Positives = 28/58 (48%), Gaps = 1/58 (1%)
Query: 2 CGHPAVPPNARVSIPNE-ENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
CG +P + ++ + N + + C +GY++ G + EC G WT +PP C
Sbjct: 200 CGELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQC 257
Score = 34.7 bits (76), Expect = 1.8
Identities = 18/59 (30%), Positives = 27/59 (45%), Gaps = 1/59 (1%)
Query: 1 RCGHPAVPPNARVSIPNEENIVA-GTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
+C VP ARV+ + ++ + C+EG L GA +C G+W PP C
Sbjct: 385 QCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPEC 443
Score = 32.3 bits (70), Expect = 9.7
Identities = 20/62 (32%), Positives = 27/62 (43%), Gaps = 3/62 (4%)
Query: 20 NIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTNVAFRKPANQSTTVRGGAA 79
N G+I + C EG L G+ Q C G W+ P C A ++ T GGA
Sbjct: 661 NFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTC---QAGPLTIQEALTYFGGAV 717
Query: 80 AN 81
A+
Sbjct: 718 AS 719
>AL022146-1|CAI22752.1| 768|Homo sapiens selectin P (granule
membrane protein 140kDa, antigen CD62) protein.
Length = 768
Score = 206 bits (504), Expect = 3e-52
Identities = 135/462 (29%), Positives = 205/462 (44%), Gaps = 49/462 (10%)
Query: 346 CQYLP-PTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPP 404
CQ+L P+ G+ D + T + GS ++C G+ + G C G WS P
Sbjct: 262 CQHLEAPSEGTMDCVHPLTA----FAYGSSCKFECQPGYRVRGLDMLRCIDSGHWSAPLP 317
Query: 405 SCKYVNCGGL-TPIEDG-DVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGE 462
+C+ ++C L +P+ D + + + C E F L G C + G W
Sbjct: 318 TCEAISCEPLESPVHGSMDCSPSLRAFQYDTNCSFRCAEGFMLRGADIVRCDNLGQWTAP 377
Query: 463 APRCLFDWCPDPPAVSNASVTVNGHKAG-----SLASYTCENGHILSGSTSVTCTLGGAW 517
AP C C D P + A V + H G S+ S+TC G +L G++ + C G W
Sbjct: 378 APVCQALQCQDLPVPNEARVNCS-HPFGAFRYQSVCSFTCNEGLLLVGASVLQCLATGNW 436
Query: 518 SGVPPSCKYVNCGTPTI--HKGSFVLIN--GTTTYGSIAQFTCEPDYWLNGAEELVCNRD 573
+ VPP C+ + C TP + G+ + G+++Y S QF C+ Y L+G E L C R
Sbjct: 437 NSVPPECQAIPC-TPLLSPQNGTMTCVQPLGSSSYKSTCQFICDEGYSLSGPERLDCTRS 495
Query: 574 GKWSYDIPSCELTSCPEPEVPSGGYMEAFD----YYVHSTINFHCEAGHKLIGEPNLVCQ 629
G+W+ P CE CPE P G ++ D + V ST +F C+ G KL G N+ C
Sbjct: 496 GRWTDSPPMCEAIKCPELFAPEQGSLDCSDTRGEFNVGSTCHFSCDNGFKLEGPNNVECT 555
Query: 630 QDGEWSGDSPTCEYI--------DCGKLPTLPYGTMELLN--GTTHLGSVIQYSCTTNYR 679
G WS PTC+ I C L T GTM + GT + + C +
Sbjct: 556 TSGRWSATPPTCKGIASLPTPGVQCPALTTPGQGTMYCRHHPGTFGFNTTCYFGCNAGFT 615
Query: 680 LVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDV 739
L+G +C QW+ +P C ++CS+ + K I N +
Sbjct: 616 LIGDSTLSCRPSGQWTAVTPACRAVKCSE-LHVNKPIAMNCSN----------------L 658
Query: 740 GNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQ 781
+ G++ + C +G + G + + C++NG WS T PTCQ
Sbjct: 659 WGNFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTCQ 700
Score = 206 bits (502), Expect = 4e-52
Identities = 172/703 (24%), Positives = 279/703 (39%), Gaps = 91/703 (12%)
Query: 236 SFDEARKQCQSHGGDLIHGFQGATSSFLTQELERRKAQLKTQLVWIGAQKEPGLTSRTWQ 295
S++ +RK CQ+ DL+ +L + L + WIG +K ++TW
Sbjct: 52 SWNISRKYCQNRYTDLVAIQNKNEIDYLNKVLP-----YYSSYYWIGIRKN----NKTWT 102
Query: 296 WVDGELV---SKPSWGKDQPNNYNGEQNCV---VLDGGRGWLWNDVGCNLDYLHWICQYL 349
WV + +W ++PNN ++CV + WND C L H +C
Sbjct: 103 WVGTKKALTNEAENWADNEPNNKRNNEDCVEIYIKSPSAPGKWNDEHC-LKKKHALCY-- 159
Query: 350 PPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYV 409
T D ++ + G +C E +G+ + C GF+ P C+YV
Sbjct: 160 --TASCQD--MSCSKQG-----------ECLE---TIGNYTCSCYP-GFYG---PECEYV 197
Query: 410 N-CGGLTPIEDGDVALID--NRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRC 466
CG L + + + ++ + C + + + G + C GIW + P+C
Sbjct: 198 RECGELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQC 257
Query: 467 LFDWCPDPPAVSNASVT----VNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPP 522
L C A S ++ + GS + C+ G+ + G + C G WS P
Sbjct: 258 LAVQCQHLEAPSEGTMDCVHPLTAFAYGSSCKFECQPGYRVRGLDMLRCIDSGHWSAPLP 317
Query: 523 SCKYVNCGT--PTIHKGSFVLINGTTT--YGSIAQFTCEPDYWLNGAEELVCNRDGKWSY 578
+C+ ++C +H GS Y + F C + L GA+ + C+ G+W+
Sbjct: 318 TCEAISCEPLESPVH-GSMDCSPSLRAFQYDTNCSFRCAEGFMLRGADIVRCDNLGQWTA 376
Query: 579 DIPSCELTSCPEPEVPSGGYME------AFDYYVHSTINFHCEAGHKLIGEPNLVCQQDG 632
P C+ C + VP+ + AF Y S +F C G L+G L C G
Sbjct: 377 PAPVCQALQCQDLPVPNEARVNCSHPFGAFRY--QSVCSFTCNEGLLLVGASVLQCLATG 434
Query: 633 EWSGDSPTCEYIDCGKLPTLPYGTMELLN--GTTHLGSVIQYSCTTNYRLVGPVRRTCTE 690
W+ P C+ I C L + GTM + G++ S Q+ C Y L GP R CT
Sbjct: 435 NWNSVPPECQAIPCTPLLSPQNGTMTCVQPLGSSSYKSTCQFICDEGYSLSGPERLDCTR 494
Query: 691 EFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVK 750
+W+DS P CE I+C + E+ + D D + +G+
Sbjct: 495 SGRWTDSPPMCEAIKCPELFAPEQG-----------------SLDCSDTRGEFNVGSTCH 537
Query: 751 YRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYV-DCGNPGRIENGKVTLPSNATFY---- 805
+ C+ G+K+ G + C +G+WS T PTC+ + PG ++ +T P T Y
Sbjct: 538 FSCDNGFKLEGPNNVECTTSGRWSATPPTCKGIASLPTPG-VQCPALTTPGQGTMYCRHH 596
Query: 806 ------GATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLL 859
T ++ C+ + L G C+ +G W+ P C+ + C +
Sbjct: 597 PGTFGFNTTCYFGCNAGFTLIGDSTLSCRPSGQWTAVTPACRAVKCSELHVNKPIAMNCS 656
Query: 860 VVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVC 902
+ S G + C G L G C G W+ TVP C
Sbjct: 657 NLWGNFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTC 699
Score = 202 bits (493), Expect = 5e-51
Identities = 132/508 (25%), Positives = 211/508 (41%), Gaps = 42/508 (8%)
Query: 479 NASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCG-TPTIHKG 537
N S + S S+ C +G+ ++G + + C G W+ PP C V C +G
Sbjct: 212 NCSHPLGNFSFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQCLAVQCQHLEAPSEG 271
Query: 538 SFVLINGTTT--YGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPS 595
+ ++ T YGS +F C+P Y + G + L C G WS +P+CE SC E P
Sbjct: 272 TMDCVHPLTAFAYGSSCKFECQPGYRVRGLDMLRCIDSGHWSAPLPTCEAISCEPLESPV 331
Query: 596 GGYME------AFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKL 649
G M+ AF Y + +F C G L G + C G+W+ +P C+ + C L
Sbjct: 332 HGSMDCSPSLRAFQY--DTNCSFRCAEGFMLRGADIVRCDNLGQWTAPAPVCQALQCQDL 389
Query: 650 PTLPYGTMELLN--GTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCS 707
P + + G SV ++C LVG C W+ P C+ I C+
Sbjct: 390 PVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPECQAIPCT 449
Query: 708 DPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTC 767
P+++ ++ T ++ + +T ++ C++GY + G C
Sbjct: 450 -PLLSPQNGTM----------TCVQPLGSSSYKST------CQFICDEGYSLSGPERLDC 492
Query: 768 EDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFY--GATAFYQCDENWELEGVIRR 825
+G+W+ + P C+ + C E G + + G+T + CD ++LEG
Sbjct: 493 TRSGRWTDSPPMCEAIKCPELFAPEQGSLDCSDTRGEFNVGSTCHFSCDNGFKLEGPNNV 552
Query: 826 MCQENGTWSLEPPICKEI-TCPDPSAQIKA----GSGLLVVT---STLSIGGEAHYQCER 877
C +G WS PP CK I + P P Q A G G + T ++ C
Sbjct: 553 ECTTSGRWSATPPTCKGIASLPTPGVQCPALTTPGQGTMYCRHHPGTFGFNTTCYFGCNA 612
Query: 878 GYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISN--GSTLFGSSVEYYC 935
G+ L G T +C GQW P C + C + + SN G+ +GS ++C
Sbjct: 613 GFTLIGDSTLSCRPSGQWTAVTPACRAVKCSELHVNKPIAMNCSNLWGNFSYGSICSFHC 672
Query: 936 LSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
L G C ++G WS P+C+
Sbjct: 673 LEGQLLNGSAQTACQENGHWSTTVPTCQ 700
Score = 189 bits (460), Expect = 5e-47
Identities = 125/489 (25%), Positives = 203/489 (41%), Gaps = 45/489 (9%)
Query: 498 ENGHILSGSTSVTCTLGGAWSGVPPSCKYVN-CGTPTIHKGSFVLIN-----GTTTYGSI 551
+ G L + TC+ + G P C+YV CG + VL+N G ++ S
Sbjct: 170 KQGECLETIGNYTCSCYPGFYG--PECEYVRECGE--LELPQHVLMNCSHPLGNFSFNSQ 225
Query: 552 AQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFD----YYVH 607
F C Y +NG +L C G W+ P C C E PS G M+ +
Sbjct: 226 CSFHCTDGYQVNGPSKLECLASGIWTNKPPQCLAVQCQHLEAPSEGTMDCVHPLTAFAYG 285
Query: 608 STINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTT--H 665
S+ F C+ G+++ G L C G WS PTCE I C L + +G+M+
Sbjct: 286 SSCKFECQPGYRVRGLDMLRCIDSGHWSAPLPTCEAISCEPLESPVHGSMDCSPSLRAFQ 345
Query: 666 LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRS 725
+ + C + L G C QW+ +P C+ ++C D V ++ V+ S
Sbjct: 346 YDTNCSFRCAEGFMLRGADIVRCDNLGQWTAPAPVCQALQCQDLPVPNEARVNC-----S 400
Query: 726 HGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDC 785
H +R ++ + C +G ++G S+ C G W+ P CQ + C
Sbjct: 401 HPF------------GAFRYQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPECQAIPC 448
Query: 786 GNPGRIENGKVTL--PSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEI 843
+NG +T P ++ Y +T + CDE + L G R C +G W+ PP+C+ I
Sbjct: 449 TPLLSPQNGTMTCVQPLGSSSYKSTCQFICDEGYSLSGPERLDCTRSGRWTDSPPMCEAI 508
Query: 844 TCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVC- 902
CP+ A + ++G H+ C+ G+ L+G C + G+W+ T P C
Sbjct: 509 KCPELFAPEQGSLDCSDTRGEFNVGSTCHFSCDNGFKLEGPNNVECTTSGRWSATPPTCK 568
Query: 903 ----IP---IDCRSPGNIENGKIVISNGSTLFGSSVEYY--CLSQYQRVGPFLRKCLDDG 953
+P + C + G + + FG + Y C + + +G C G
Sbjct: 569 GIASLPTPGVQCPALTTPGQGTMYCRHHPGTFGFNTTCYFGCNAGFTLIGDSTLSCRPSG 628
Query: 954 RWSGEEPSC 962
+W+ P+C
Sbjct: 629 QWTAVTPAC 637
Score = 132 bits (318), Expect = 9e-30
Identities = 83/332 (25%), Positives = 130/332 (39%), Gaps = 24/332 (7%)
Query: 639 PTCEYI-DCGKLPTLPYGTMELLN--GTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWS 695
P CEY+ +CG+L + M + G S + CT Y++ GP + C W+
Sbjct: 192 PECEYVRECGELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPSKLECLASGIWT 251
Query: 696 DSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEK 755
+ P+C ++C + + H L + G+ K+ C+
Sbjct: 252 NKPPQCLAVQCQHLEAPSEGTMDCV-------HPL----------TAFAYGSSCKFECQP 294
Query: 756 GYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTL-PSNATF-YGATAFYQC 813
GY+V G + C D+G WS PTC+ + C +G + PS F Y ++C
Sbjct: 295 GYRVRGLDMLRCIDSGHWSAPLPTCEAISCEPLESPVHGSMDCSPSLRAFQYDTNCSFRC 354
Query: 814 DENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHY 873
E + L G C G W+ P+C+ + C D +A +
Sbjct: 355 AEGFMLRGADIVRCDNLGQWTAPAPVCQALQCQDLPVPNEARVNCSHPFGAFRYQSVCSF 414
Query: 874 QCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISN--GSTLFGSSV 931
C G L G C++ G WN P C I C + +NG + GS+ + S+
Sbjct: 415 TCNEGLLLVGASVLQCLATGNWNSVPPECQAIPCTPLLSPQNGTMTCVQPLGSSSYKSTC 474
Query: 932 EYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
++ C Y GP C GRW+ P CE
Sbjct: 475 QFICDEGYSLSGPERLDCTRSGRWTDSPPMCE 506
Score = 63.7 bits (148), Expect = 3e-09
Identities = 30/109 (27%), Positives = 50/109 (45%), Gaps = 2/109 (1%)
Query: 866 SIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGST 925
S + + C GY + G C++ G W P C+ + C+ G + + T
Sbjct: 221 SFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQCLAVQCQHLEAPSEGTMDCVHPLT 280
Query: 926 LF--GSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCELATNEAVDS 972
F GSS ++ C Y+ G + +C+D G WS P+CE + E ++S
Sbjct: 281 AFAYGSSCKFECQPGYRVRGLDMLRCIDSGHWSAPLPTCEAISCEPLES 329
Score = 40.7 bits (91), Expect = 0.028
Identities = 15/28 (53%), Positives = 17/28 (60%)
Query: 31 CDEGYELFGARQRECTLRGDWTLEPPFC 58
CDEGY L G + +CT G WT PP C
Sbjct: 478 CDEGYSLSGPERLDCTRSGRWTDSPPMC 505
Score = 38.7 bits (86), Expect = 0.11
Identities = 14/35 (40%), Positives = 19/35 (54%)
Query: 24 GTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
G+ + CD G++L G ECT G W+ PP C
Sbjct: 533 GSTCHFSCDNGFKLEGPNNVECTTSGRWSATPPTC 567
Score = 35.9 bits (79), Expect = 0.79
Identities = 16/58 (27%), Positives = 28/58 (48%), Gaps = 1/58 (1%)
Query: 2 CGHPAVPPNARVSIPNE-ENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
CG +P + ++ + N + + C +GY++ G + EC G WT +PP C
Sbjct: 200 CGELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQC 257
Score = 34.7 bits (76), Expect = 1.8
Identities = 18/59 (30%), Positives = 27/59 (45%), Gaps = 1/59 (1%)
Query: 1 RCGHPAVPPNARVSIPNEENIVA-GTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
+C VP ARV+ + ++ + C+EG L GA +C G+W PP C
Sbjct: 385 QCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPEC 443
Score = 32.3 bits (70), Expect = 9.7
Identities = 20/62 (32%), Positives = 27/62 (43%), Gaps = 3/62 (4%)
Query: 20 NIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTNVAFRKPANQSTTVRGGAA 79
N G+I + C EG L G+ Q C G W+ P C A ++ T GGA
Sbjct: 661 NFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTC---QAGPLTIQEALTYFGGAV 717
Query: 80 AN 81
A+
Sbjct: 718 AS 719
>M62486-1|AAA36506.1| 597|Homo sapiens C4b-binding protein alpha
chain protein.
Length = 597
Score = 187 bits (455), Expect = 2e-46
Identities = 147/527 (27%), Positives = 231/527 (43%), Gaps = 55/527 (10%)
Query: 471 CPDPPAVSNAS-----VTVNGHKAGSLASYTCENGHILSGST-SVTCTLGGAWSGVPPSC 524
C PP +S A+ +T K G+ YTC G++ S ST ++TC G W C
Sbjct: 50 CGPPPTLSFAAPMDITLTETRFKTGTTLKYTCLPGYVRSHSTQTLTCNSDGEWV-YNTFC 108
Query: 525 KYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVC---NRDGKWSYDIP 581
Y C P + V I ++GS +F+C ++L G+ C +R WS+ +P
Sbjct: 109 IYKRCRHPGELRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRGVGWSHPLP 168
Query: 582 SCELTSC-PEPEVPSGGYMEAFDYYVHS-TINFHCEAGHKLIGEPNLVCQQDGE----WS 635
CE+ C P P++ +G + ++Y + ++ + C+ L+G ++ C + E W
Sbjct: 169 QCEIVKCKPPPDIRNGRHSGEENFYAYGFSVTYSCDPRFSLLGHASISCTVENETIGVWR 228
Query: 636 GDSPTCEYIDCGKLPTLPYGTMELLNGTTH-LGSVIQYSCTTNYRLVGPVRRTCTEEFQW 694
PTCE I C K P + +G M G + I + C + L G C + +W
Sbjct: 229 PSPPTCEKITCRK-PDVSHGEMVSGFGPIYNYKDTIVFKCQKGFVLRGSSVIHCDADSKW 287
Query: 695 SDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCE 754
+ S P CE C +++ + T R + DV Y +G +++YRC
Sbjct: 288 NPSPPACEPNSC----------INLPDIPHASWETYPRPT-KEDV---YVVGTVLRYRCH 333
Query: 755 KGYKVIGESLST--CEDNGQWSGTTPTCQYVDCGNPGRIENGKVTL-----PSN--ATFY 805
GYK + +T C+ N +W+ C+ + C P ++ NG++T P+N FY
Sbjct: 334 PGYKPTTDEPTTVICQKNLRWT-PYQGCEALCCPEP-KLNNGEITQHRKSRPANHCVYFY 391
Query: 806 GATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTL 865
G + C E + CQ +GTWS P C +I C P K G +S+
Sbjct: 392 GDEISFSCHETSRFSAI----CQGDGTWSPRTPSCGDI-CNFPP---KIAHGHYKQSSSY 443
Query: 866 SI-GGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGS 924
S E Y+C++GY L G +C S W+ P C + CR P + NG++ +
Sbjct: 444 SFFKEEIIYECDKGYILVGQAKLSC-SYSHWSAPAPQCKAL-CRKP-ELVNGRLSVDKDQ 500
Query: 925 TLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCELATNEAVD 971
+ +V C S Y VGP C + W E P CE T E +
Sbjct: 501 YVEPENVTIQCDSGYGVVGPQSITCSGNRTWYPEVPKCEWETPEGCE 547
Score = 173 bits (421), Expect = 3e-42
Identities = 131/502 (26%), Positives = 205/502 (40%), Gaps = 46/502 (9%)
Query: 421 DVALIDNRTTHGARALYSCRENFTLVGNPER-TCGDEGIWDGEAPRCLFDWCPDPPAVSN 479
D+ L + R G Y+C + + + TC +G W C++ C P + N
Sbjct: 63 DITLTETRFKTGTTLKYTCLPGYVRSHSTQTLTCNSDGEWVYNT-FCIYKRCRHPGELRN 121
Query: 480 ASVTVNGHKA-GSLASYTCENGHILSGSTSVTCTL---GGAWSGVPPSCKYVNCGTPT-I 534
V + + GS ++C G L GST+ C + G WS P C+ V C P I
Sbjct: 122 GQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRGVGWSHPLPQCEIVKCKPPPDI 181
Query: 535 HKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRD----GKWSYDIPSCELTSCPE 590
G YG ++C+P + L G + C + G W P+CE +C +
Sbjct: 182 RNGRHSGEENFYAYGFSVTYSCDPRFSLLGHASISCTVENETIGVWRPSPPTCEKITCRK 241
Query: 591 PEVPSGGYMEAFD--YYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGK 648
P+V G + F Y TI F C+ G L G + C D +W+ P CE C
Sbjct: 242 PDVSHGEMVSGFGPIYNYKDTIVFKCQKGFVLRGSSVIHCDADSKWNPSPPACEPNSCIN 301
Query: 649 LPTLPYGTMELLNGTTH-----LGSVIQYSCTTNYRLV--GPVRRTCTEEFQWSDSSPRC 701
LP +P+ + E T +G+V++Y C Y+ P C + +W+ C
Sbjct: 302 LPDIPHASWETYPRPTKEDVYVVGTVLRYRCHPGYKPTTDEPTTVICQKNLRWTPYQ-GC 360
Query: 702 EEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIG 761
E + C +P + I H R +++ Y G + + C +
Sbjct: 361 EALCCPEPKLNNGEITQ---------HRKSRPANH----CVYFYGDEISFSCHE----TS 403
Query: 762 ESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEG 821
+ C+ +G WS TP+C + C P +I +G S+ +F+ Y+CD+ + L G
Sbjct: 404 RFSAICQGDGTWSPRTPSCGDI-CNFPPKIAHGHYKQSSSYSFFKEEIIYECDKGYILVG 462
Query: 822 VIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGE-AHYQCERGYN 880
+ C + WS P CK + C P + +G L V + E QC+ GY
Sbjct: 463 QAKLSCSYS-HWSAPAPQCKAL-CRKP----ELVNGRLSVDKDQYVEPENVTIQCDSGYG 516
Query: 881 LKGHQTRTCISKGQWNGTVPVC 902
+ G Q+ TC W VP C
Sbjct: 517 VVGPQSITCSGNRTWYPEVPKC 538
Score = 148 bits (358), Expect = 1e-34
Identities = 117/456 (25%), Positives = 189/456 (41%), Gaps = 54/456 (11%)
Query: 353 CGSPDKLLNTTI-LGNDYDVGSRIVYKCPEGHMLLGDKSRHCK---KDGFWSGAPPSCKY 408
C P +L N + + D GS+I + C EG L+G + C+ + WS P C+
Sbjct: 113 CRHPGELRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRGVGWSHPLPQCEI 172
Query: 409 VNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDE----GIWDGEAP 464
V C I +G + +N +G YSC F+L+G+ +C E G+W P
Sbjct: 173 VKCKPPPDIRNGRHSGEENFYAYGFSVTYSCDPRFSLLGHASISCTVENETIGVWRPSPP 232
Query: 465 RCLFDWCPDPPAVSNASVTVNG--HKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPP 522
C C P V+ G + + C+ G +L GS+ + C W+ PP
Sbjct: 233 TCEKITCRKPDVSHGEMVSGFGPIYNYKDTIVFKCQKGFVLRGSSVIHCDADSKWNPSPP 292
Query: 523 SCKYVNC-GTPTIHKGSFVLINGTT-----TYGSIAQFTCEPDYWLNGAE--ELVCNRDG 574
+C+ +C P I S+ T G++ ++ C P Y E ++C ++
Sbjct: 293 ACEPNSCINLPDIPHASWETYPRPTKEDVYVVGTVLRYRCHPGYKPTTDEPTTVICQKNL 352
Query: 575 KWSYDIPSCELTSCPEPEVPSGGYMEAFD--------YYVHSTINFHCEAGHKLIGEPNL 626
+W+ CE CPEP++ +G + Y+ I+F C + +
Sbjct: 353 RWT-PYQGCEALCCPEPKLNNGEITQHRKSRPANHCVYFYGDEISFSCHETSRF----SA 407
Query: 627 VCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRR 686
+CQ DG WS +P+C I C P + +G + + + I Y C Y LVG +
Sbjct: 408 ICQGDGTWSPRTPSCGDI-CNFPPKIAHGHYKQSSSYSFFKEEIIYECDKGYILVGQAKL 466
Query: 687 TCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIG 746
+C+ WS +P+C+ + C P + V G R S ++D Y
Sbjct: 467 SCSYS-HWSAPAPQCKAL-CRKPEL-------VNG----------RLSVDKD---QYVEP 504
Query: 747 ALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQY 782
V +C+ GY V+G TC N W P C++
Sbjct: 505 ENVTIQCDSGYGVVGPQSITCSGNRTWYPEVPKCEW 540
Score = 128 bits (308), Expect = 1e-28
Identities = 120/460 (26%), Positives = 176/460 (38%), Gaps = 51/460 (11%)
Query: 528 NCGTP-TIHKGSFVLINGTTTY---GSIAQFTCEPDYWLN-GAEELVCNRDGKWSYDIPS 582
NCG P T+ + + I T T G+ ++TC P Y + + L CN DG+W Y+
Sbjct: 49 NCGPPPTLSFAAPMDITLTETRFKTGTTLKYTCLPGYVRSHSTQTLTCNSDGEWVYNT-F 107
Query: 583 CELTSCPEPEVPSGGYMEA-FDYYVHSTINFHCEAGHKLIGEPNLVCQ-QDGE--WSGDS 638
C C P G +E D S I F C G LIG C+ QD WS
Sbjct: 108 CIYKRCRHPGELRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRGVGWSHPL 167
Query: 639 PTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQ----W 694
P CE + C P + G G + YSC + L+G +CT E + W
Sbjct: 168 PQCEIVKCKPPPDIRNGRHSGEENFYAYGFSVTYSCDPRFSLLGHASISCTVENETIGVW 227
Query: 695 SDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCE 754
S P CE+I C P D SHG + G Y + ++C+
Sbjct: 228 RPSPPTCEKITCRKP-------------DVSHGEMV------SGFGPIYNYKDTIVFKCQ 268
Query: 755 KGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGK---VTLPSNATFY--GATA 809
KG+ + G S+ C+ + +W+ + P C+ C N I + P+ Y G
Sbjct: 269 KGFVLRGSSVIHCDADSKWNPSPPACEPNSCINLPDIPHASWETYPRPTKEDVYVVGTVL 328
Query: 810 FYQCDENWE--LEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSI 867
Y+C ++ + +CQ+N W+ C+ + CP+P K +G +
Sbjct: 329 RYRCHPGYKPTTDEPTTVICQKNLRWTPYQG-CEALCCPEP----KLNNGEITQHRKSRP 383
Query: 868 GGEAHYQCERGYNLKGHQT----RTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNG 923
Y + H+T C G W+ P C I C P I +G S+
Sbjct: 384 ANHCVYFYGDEISFSCHETSRFSAICQGDGTWSPRTPSCGDI-CNFPPKIAHGHYKQSSS 442
Query: 924 STLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
+ F + Y C Y VG C WS P C+
Sbjct: 443 YSFFKEEIIYECDKGYILVGQAKLSC-SYSHWSAPAPQCK 481
Score = 91.5 bits (217), Expect = 2e-17
Identities = 75/311 (24%), Positives = 119/311 (38%), Gaps = 27/311 (8%)
Query: 352 TCGSPDKLLNTTI--LGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYV 409
TC PD + G Y+ IV+KC +G +L G HC D W+ +PP+C+
Sbjct: 238 TCRKPDVSHGEMVSGFGPIYNYKDTIVFKCQKGFVLRGSSVIHCDADSKWNPSPPACEPN 297
Query: 410 NCGGLTPIEDGDVALIDNRTTH-----GARALYSCRENFTLVGNPERT--CGDEGIWDGE 462
+C L I T G Y C + + T C W
Sbjct: 298 SCINLPDIPHASWETYPRPTKEDVYVVGTVLRYRCHPGYKPTTDEPTTVICQKNLRWT-P 356
Query: 463 APRCLFDWCPDPPAVSNASVTVNGHKA---------GSLASYTCENGHILSGSTSVTCTL 513
C CP+ P ++N +T + G S++C + S C
Sbjct: 357 YQGCEALCCPE-PKLNNGEITQHRKSRPANHCVYFYGDEISFSCHE----TSRFSAICQG 411
Query: 514 GGAWSGVPPSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRD 573
G WS PSC + P I G + + + + + C+ Y L G +L C+
Sbjct: 412 DGTWSPRTPSCGDICNFPPKIAHGHYKQSSSYSFFKEEIIYECDKGYILVGQAKLSCSY- 470
Query: 574 GKWSYDIPSCELTSCPEPEVPSGGYMEAFDYYVH-STINFHCEAGHKLIGEPNLVCQQDG 632
WS P C+ C +PE+ +G D YV + C++G+ ++G ++ C +
Sbjct: 471 SHWSAPAPQCK-ALCRKPELVNGRLSVDKDQYVEPENVTIQCDSGYGVVGPQSITCSGNR 529
Query: 633 EWSGDSPTCEY 643
W + P CE+
Sbjct: 530 TWYPEVPKCEW 540
Score = 34.3 bits (75), Expect = 2.4
Identities = 25/72 (34%), Positives = 29/72 (40%), Gaps = 8/72 (11%)
Query: 1 RCGHPAVPPNARVSIPNEENIVA-GTIAVYECDEGYELFGARQRECTLR----GDWTLEP 55
+C P N R S EEN A G Y CD + L G CT+ G W P
Sbjct: 174 KCKPPPDIRNGRHS--GEENFYAYGFSVTYSCDPRFSLLGHASISCTVENETIGVWRPSP 231
Query: 56 PFCGTNVAFRKP 67
P C + RKP
Sbjct: 232 PTC-EKITCRKP 242
>M31452-1|AAA36507.1| 597|Homo sapiens C4b-binding protein alpha
chain protein.
Length = 597
Score = 187 bits (455), Expect = 2e-46
Identities = 147/527 (27%), Positives = 231/527 (43%), Gaps = 55/527 (10%)
Query: 471 CPDPPAVSNAS-----VTVNGHKAGSLASYTCENGHILSGST-SVTCTLGGAWSGVPPSC 524
C PP +S A+ +T K G+ YTC G++ S ST ++TC G W C
Sbjct: 50 CGPPPTLSFAAPMDITLTETRFKTGTTLKYTCLPGYVRSHSTQTLTCNSDGEWV-YNTFC 108
Query: 525 KYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVC---NRDGKWSYDIP 581
Y C P + V I ++GS +F+C ++L G+ C +R WS+ +P
Sbjct: 109 IYKRCRHPGELRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRGVGWSHPLP 168
Query: 582 SCELTSC-PEPEVPSGGYMEAFDYYVHS-TINFHCEAGHKLIGEPNLVCQQDGE----WS 635
CE+ C P P++ +G + ++Y + ++ + C+ L+G ++ C + E W
Sbjct: 169 QCEIVKCKPPPDIRNGRHSGEENFYAYGFSVTYSCDPRFSLLGHASISCTVENETIGVWR 228
Query: 636 GDSPTCEYIDCGKLPTLPYGTMELLNGTTH-LGSVIQYSCTTNYRLVGPVRRTCTEEFQW 694
PTCE I C K P + +G M G + I + C + L G C + +W
Sbjct: 229 PSPPTCEKITCRK-PDVSHGEMVSGFGPIYNYKDTIVFKCQKGFVLRGSSVIHCDADSKW 287
Query: 695 SDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCE 754
+ S P CE C +++ + T R + DV Y +G +++YRC
Sbjct: 288 NPSPPACEPNSC----------INLPDIPHASWETYPRPT-KEDV---YVVGTVLRYRCH 333
Query: 755 KGYKVIGESLST--CEDNGQWSGTTPTCQYVDCGNPGRIENGKVTL-----PSN--ATFY 805
GYK + +T C+ N +W+ C+ + C P ++ NG++T P+N FY
Sbjct: 334 PGYKPTTDEPTTVICQKNLRWT-PYQGCEALCCPEP-KLNNGEITQHRKSRPANHCVYFY 391
Query: 806 GATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTL 865
G + C E + CQ +GTWS P C +I C P K G +S+
Sbjct: 392 GDEISFSCHETSRFSAI----CQGDGTWSPRTPSCGDI-CNFPP---KIAHGHYKQSSSY 443
Query: 866 SI-GGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGS 924
S E Y+C++GY L G +C S W+ P C + CR P + NG++ +
Sbjct: 444 SFFKEEIIYECDKGYILVGQAKLSC-SYSHWSAPAPQCKAL-CRKP-ELVNGRLSVDKDQ 500
Query: 925 TLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCELATNEAVD 971
+ +V C S Y VGP C + W E P CE T E +
Sbjct: 501 YVEPENVTIQCDSGYGVVGPQSITCSGNRTWYPEVPKCEWETPEGCE 547
Score = 173 bits (421), Expect = 3e-42
Identities = 131/502 (26%), Positives = 205/502 (40%), Gaps = 46/502 (9%)
Query: 421 DVALIDNRTTHGARALYSCRENFTLVGNPER-TCGDEGIWDGEAPRCLFDWCPDPPAVSN 479
D+ L + R G Y+C + + + TC +G W C++ C P + N
Sbjct: 63 DITLTETRFKTGTTLKYTCLPGYVRSHSTQTLTCNSDGEWVYNT-FCIYKRCRHPGELRN 121
Query: 480 ASVTVNGHKA-GSLASYTCENGHILSGSTSVTCTL---GGAWSGVPPSCKYVNCGTPT-I 534
V + + GS ++C G L GST+ C + G WS P C+ V C P I
Sbjct: 122 GQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRGVGWSHPLPQCEIVKCKPPPDI 181
Query: 535 HKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRD----GKWSYDIPSCELTSCPE 590
G YG ++C+P + L G + C + G W P+CE +C +
Sbjct: 182 RNGRHSGEENFYAYGFSVTYSCDPRFSLLGHASISCTVENETIGVWRPSPPTCEKITCRK 241
Query: 591 PEVPSGGYMEAFD--YYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGK 648
P+V G + F Y TI F C+ G L G + C D +W+ P CE C
Sbjct: 242 PDVSHGEMVSGFGPIYNYKDTIVFKCQKGFVLRGSSVIHCDADSKWNPSPPACEPNSCIN 301
Query: 649 LPTLPYGTMELLNGTTH-----LGSVIQYSCTTNYRLV--GPVRRTCTEEFQWSDSSPRC 701
LP +P+ + E T +G+V++Y C Y+ P C + +W+ C
Sbjct: 302 LPDIPHASWETYPRPTKEDVYVVGTVLRYRCHPGYKPTTDEPTTVICQKNLRWTPYQ-GC 360
Query: 702 EEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIG 761
E + C +P + I H R +++ Y G + + C +
Sbjct: 361 EALCCPEPKLNNGEITQ---------HRKSRPANH----CVYFYGDEISFSCHE----TS 403
Query: 762 ESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEG 821
+ C+ +G WS TP+C + C P +I +G S+ +F+ Y+CD+ + L G
Sbjct: 404 RFSAICQGDGTWSPRTPSCGDI-CNFPPKIAHGHYKQSSSYSFFKEEIIYECDKGYILVG 462
Query: 822 VIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGE-AHYQCERGYN 880
+ C + WS P CK + C P + +G L V + E QC+ GY
Sbjct: 463 QAKLSCSYS-HWSAPAPQCKAL-CRKP----ELVNGRLSVDKDQYVEPENVTIQCDSGYG 516
Query: 881 LKGHQTRTCISKGQWNGTVPVC 902
+ G Q+ TC W VP C
Sbjct: 517 VVGPQSITCSGNRTWYPEVPKC 538
Score = 148 bits (358), Expect = 1e-34
Identities = 117/456 (25%), Positives = 189/456 (41%), Gaps = 54/456 (11%)
Query: 353 CGSPDKLLNTTI-LGNDYDVGSRIVYKCPEGHMLLGDKSRHCK---KDGFWSGAPPSCKY 408
C P +L N + + D GS+I + C EG L+G + C+ + WS P C+
Sbjct: 113 CRHPGELRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRGVGWSHPLPQCEI 172
Query: 409 VNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDE----GIWDGEAP 464
V C I +G + +N +G YSC F+L+G+ +C E G+W P
Sbjct: 173 VKCKPPPDIRNGRHSGEENFYAYGFSVTYSCDPRFSLLGHASISCTVENETIGVWRPSPP 232
Query: 465 RCLFDWCPDPPAVSNASVTVNG--HKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPP 522
C C P V+ G + + C+ G +L GS+ + C W+ PP
Sbjct: 233 TCEKITCRKPDVSHGEMVSGFGPIYNYKDTIVFKCQKGFVLRGSSVIHCDADSKWNPSPP 292
Query: 523 SCKYVNC-GTPTIHKGSFVLINGTT-----TYGSIAQFTCEPDYWLNGAE--ELVCNRDG 574
+C+ +C P I S+ T G++ ++ C P Y E ++C ++
Sbjct: 293 ACEPNSCINLPDIPHASWETYPRPTKEDVYVVGTVLRYRCHPGYKPTTDEPTTVICQKNL 352
Query: 575 KWSYDIPSCELTSCPEPEVPSGGYMEAFD--------YYVHSTINFHCEAGHKLIGEPNL 626
+W+ CE CPEP++ +G + Y+ I+F C + +
Sbjct: 353 RWT-PYQGCEALCCPEPKLNNGEITQHRKSRPANHCVYFYGDEISFSCHETSRF----SA 407
Query: 627 VCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRR 686
+CQ DG WS +P+C I C P + +G + + + I Y C Y LVG +
Sbjct: 408 ICQGDGTWSPRTPSCGDI-CNFPPKIAHGHYKQSSSYSFFKEEIIYECDKGYILVGQAKL 466
Query: 687 TCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIG 746
+C+ WS +P+C+ + C P + V G R S ++D Y
Sbjct: 467 SCSYS-HWSAPAPQCKAL-CRKPEL-------VNG----------RLSVDKD---QYVEP 504
Query: 747 ALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQY 782
V +C+ GY V+G TC N W P C++
Sbjct: 505 ENVTIQCDSGYGVVGPQSITCSGNRTWYPEVPKCEW 540
Score = 128 bits (308), Expect = 1e-28
Identities = 120/460 (26%), Positives = 176/460 (38%), Gaps = 51/460 (11%)
Query: 528 NCGTP-TIHKGSFVLINGTTTY---GSIAQFTCEPDYWLN-GAEELVCNRDGKWSYDIPS 582
NCG P T+ + + I T T G+ ++TC P Y + + L CN DG+W Y+
Sbjct: 49 NCGPPPTLSFAAPMDITLTETRFKTGTTLKYTCLPGYVRSHSTQTLTCNSDGEWVYNT-F 107
Query: 583 CELTSCPEPEVPSGGYMEA-FDYYVHSTINFHCEAGHKLIGEPNLVCQ-QDGE--WSGDS 638
C C P G +E D S I F C G LIG C+ QD WS
Sbjct: 108 CIYKRCRHPGELRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRGVGWSHPL 167
Query: 639 PTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQ----W 694
P CE + C P + G G + YSC + L+G +CT E + W
Sbjct: 168 PQCEIVKCKPPPDIRNGRHSGEENFYAYGFSVTYSCDPRFSLLGHASISCTVENETIGVW 227
Query: 695 SDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCE 754
S P CE+I C P D SHG + G Y + ++C+
Sbjct: 228 RPSPPTCEKITCRKP-------------DVSHGEMV------SGFGPIYNYKDTIVFKCQ 268
Query: 755 KGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGK---VTLPSNATFY--GATA 809
KG+ + G S+ C+ + +W+ + P C+ C N I + P+ Y G
Sbjct: 269 KGFVLRGSSVIHCDADSKWNPSPPACEPNSCINLPDIPHASWETYPRPTKEDVYVVGTVL 328
Query: 810 FYQCDENWE--LEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSI 867
Y+C ++ + +CQ+N W+ C+ + CP+P K +G +
Sbjct: 329 RYRCHPGYKPTTDEPTTVICQKNLRWTPYQG-CEALCCPEP----KLNNGEITQHRKSRP 383
Query: 868 GGEAHYQCERGYNLKGHQT----RTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNG 923
Y + H+T C G W+ P C I C P I +G S+
Sbjct: 384 ANHCVYFYGDEISFSCHETSRFSAICQGDGTWSPRTPSCGDI-CNFPPKIAHGHYKQSSS 442
Query: 924 STLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
+ F + Y C Y VG C WS P C+
Sbjct: 443 YSFFKEEIIYECDKGYILVGQAKLSC-SYSHWSAPAPQCK 481
Score = 91.5 bits (217), Expect = 2e-17
Identities = 75/311 (24%), Positives = 119/311 (38%), Gaps = 27/311 (8%)
Query: 352 TCGSPDKLLNTTI--LGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYV 409
TC PD + G Y+ IV+KC +G +L G HC D W+ +PP+C+
Sbjct: 238 TCRKPDVSHGEMVSGFGPIYNYKDTIVFKCQKGFVLRGSSVIHCDADSKWNPSPPACEPN 297
Query: 410 NCGGLTPIEDGDVALIDNRTTH-----GARALYSCRENFTLVGNPERT--CGDEGIWDGE 462
+C L I T G Y C + + T C W
Sbjct: 298 SCINLPDIPHASWETYPRPTKEDVYVVGTVLRYRCHPGYKPTTDEPTTVICQKNLRWT-P 356
Query: 463 APRCLFDWCPDPPAVSNASVTVNGHKA---------GSLASYTCENGHILSGSTSVTCTL 513
C CP+ P ++N +T + G S++C + S C
Sbjct: 357 YQGCEALCCPE-PKLNNGEITQHRKSRPANHCVYFYGDEISFSCHE----TSRFSAICQG 411
Query: 514 GGAWSGVPPSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRD 573
G WS PSC + P I G + + + + + C+ Y L G +L C+
Sbjct: 412 DGTWSPRTPSCGDICNFPPKIAHGHYKQSSSYSFFKEEIIYECDKGYILVGQAKLSCSY- 470
Query: 574 GKWSYDIPSCELTSCPEPEVPSGGYMEAFDYYVH-STINFHCEAGHKLIGEPNLVCQQDG 632
WS P C+ C +PE+ +G D YV + C++G+ ++G ++ C +
Sbjct: 471 SHWSAPAPQCK-ALCRKPELVNGRLSVDKDQYVEPENVTIQCDSGYGVVGPQSITCSGNR 529
Query: 633 EWSGDSPTCEY 643
W + P CE+
Sbjct: 530 TWYPEVPKCEW 540
Score = 34.3 bits (75), Expect = 2.4
Identities = 25/72 (34%), Positives = 29/72 (40%), Gaps = 8/72 (11%)
Query: 1 RCGHPAVPPNARVSIPNEENIVA-GTIAVYECDEGYELFGARQRECTLR----GDWTLEP 55
+C P N R S EEN A G Y CD + L G CT+ G W P
Sbjct: 174 KCKPPPDIRNGRHS--GEENFYAYGFSVTYSCDPRFSLLGHASISCTVENETIGVWRPSP 231
Query: 56 PFCGTNVAFRKP 67
P C + RKP
Sbjct: 232 PTC-EKITCRKP 242
>BC022312-1|AAH22312.1| 597|Homo sapiens complement component 4
binding protein, alpha protein.
Length = 597
Score = 187 bits (455), Expect = 2e-46
Identities = 147/527 (27%), Positives = 231/527 (43%), Gaps = 55/527 (10%)
Query: 471 CPDPPAVSNAS-----VTVNGHKAGSLASYTCENGHILSGST-SVTCTLGGAWSGVPPSC 524
C PP +S A+ +T K G+ YTC G++ S ST ++TC G W C
Sbjct: 50 CGPPPTLSFAAPMDITLTETRFKTGTTLKYTCLPGYVRSHSTQTLTCNSDGEWV-YNTFC 108
Query: 525 KYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVC---NRDGKWSYDIP 581
Y C P + V I ++GS +F+C ++L G+ C +R WS+ +P
Sbjct: 109 IYKRCRHPGELRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRGVGWSHPLP 168
Query: 582 SCELTSC-PEPEVPSGGYMEAFDYYVHS-TINFHCEAGHKLIGEPNLVCQQDGE----WS 635
CE+ C P P++ +G + ++Y + ++ + C+ L+G ++ C + E W
Sbjct: 169 QCEIVKCKPPPDIRNGRHSGEENFYAYGFSVTYSCDPRFSLLGHASISCTVENETIGVWR 228
Query: 636 GDSPTCEYIDCGKLPTLPYGTMELLNGTTH-LGSVIQYSCTTNYRLVGPVRRTCTEEFQW 694
PTCE I C K P + +G M G + I + C + L G C + +W
Sbjct: 229 PSPPTCEKITCRK-PDVSHGEMVSGFGPIYNYKDTIVFKCQKGFVLRGSSVIHCDADSKW 287
Query: 695 SDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCE 754
+ S P CE C +++ + T R + DV Y +G +++YRC
Sbjct: 288 NPSPPACEPNSC----------INLPDIPHASWETYPRPT-KEDV---YVVGTVLRYRCH 333
Query: 755 KGYKVIGESLST--CEDNGQWSGTTPTCQYVDCGNPGRIENGKVTL-----PSN--ATFY 805
GYK + +T C+ N +W+ C+ + C P ++ NG++T P+N FY
Sbjct: 334 PGYKPTTDEPTTVICQKNLRWT-PYQGCEALCCPEP-KLNNGEITQHRKSRPANHCVYFY 391
Query: 806 GATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTL 865
G + C E + CQ +GTWS P C +I C P K G +S+
Sbjct: 392 GDEISFSCHETSRFSAI----CQGDGTWSPRTPSCGDI-CNFPP---KIAHGHYKQSSSY 443
Query: 866 SI-GGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGS 924
S E Y+C++GY L G +C S W+ P C + CR P + NG++ +
Sbjct: 444 SFFKEEIIYECDKGYILVGQAKLSC-SYSHWSAPAPQCKAL-CRKP-ELVNGRLSVDKDQ 500
Query: 925 TLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCELATNEAVD 971
+ +V C S Y VGP C + W E P CE T E +
Sbjct: 501 YVEPENVTIQCDSGYGVVGPQSITCSGNRTWYPEVPKCEWETPEGCE 547
Score = 173 bits (421), Expect = 3e-42
Identities = 131/502 (26%), Positives = 205/502 (40%), Gaps = 46/502 (9%)
Query: 421 DVALIDNRTTHGARALYSCRENFTLVGNPER-TCGDEGIWDGEAPRCLFDWCPDPPAVSN 479
D+ L + R G Y+C + + + TC +G W C++ C P + N
Sbjct: 63 DITLTETRFKTGTTLKYTCLPGYVRSHSTQTLTCNSDGEWVYNT-FCIYKRCRHPGELRN 121
Query: 480 ASVTVNGHKA-GSLASYTCENGHILSGSTSVTCTL---GGAWSGVPPSCKYVNCGTPT-I 534
V + + GS ++C G L GST+ C + G WS P C+ V C P I
Sbjct: 122 GQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRGVGWSHPLPQCEIVKCKPPPDI 181
Query: 535 HKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRD----GKWSYDIPSCELTSCPE 590
G YG ++C+P + L G + C + G W P+CE +C +
Sbjct: 182 RNGRHSGEENFYAYGFSVTYSCDPRFSLLGHASISCTVENETIGVWRPSPPTCEKITCRK 241
Query: 591 PEVPSGGYMEAFD--YYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGK 648
P+V G + F Y TI F C+ G L G + C D +W+ P CE C
Sbjct: 242 PDVSHGEMVSGFGPIYNYKDTIVFKCQKGFVLRGSSVIHCDADSKWNPSPPACEPNSCIN 301
Query: 649 LPTLPYGTMELLNGTTH-----LGSVIQYSCTTNYRLV--GPVRRTCTEEFQWSDSSPRC 701
LP +P+ + E T +G+V++Y C Y+ P C + +W+ C
Sbjct: 302 LPDIPHASWETYPRPTKEDVYVVGTVLRYRCHPGYKPTTDEPTTVICQKNLRWTPYQ-GC 360
Query: 702 EEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIG 761
E + C +P + I H R +++ Y G + + C +
Sbjct: 361 EALCCPEPKLNNGEITQ---------HRKSRPANH----CVYFYGDEISFSCHE----TS 403
Query: 762 ESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEG 821
+ C+ +G WS TP+C + C P +I +G S+ +F+ Y+CD+ + L G
Sbjct: 404 RFSAICQGDGTWSPRTPSCGDI-CNFPPKIAHGHYKQSSSYSFFKEEIIYECDKGYILVG 462
Query: 822 VIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGE-AHYQCERGYN 880
+ C + WS P CK + C P + +G L V + E QC+ GY
Sbjct: 463 QAKLSCSYS-HWSAPAPQCKAL-CRKP----ELVNGRLSVDKDQYVEPENVTIQCDSGYG 516
Query: 881 LKGHQTRTCISKGQWNGTVPVC 902
+ G Q+ TC W VP C
Sbjct: 517 VVGPQSITCSGNRTWYPEVPKC 538
Score = 148 bits (358), Expect = 1e-34
Identities = 117/456 (25%), Positives = 189/456 (41%), Gaps = 54/456 (11%)
Query: 353 CGSPDKLLNTTI-LGNDYDVGSRIVYKCPEGHMLLGDKSRHCK---KDGFWSGAPPSCKY 408
C P +L N + + D GS+I + C EG L+G + C+ + WS P C+
Sbjct: 113 CRHPGELRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRGVGWSHPLPQCEI 172
Query: 409 VNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDE----GIWDGEAP 464
V C I +G + +N +G YSC F+L+G+ +C E G+W P
Sbjct: 173 VKCKPPPDIRNGRHSGEENFYAYGFSVTYSCDPRFSLLGHASISCTVENETIGVWRPSPP 232
Query: 465 RCLFDWCPDPPAVSNASVTVNG--HKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPP 522
C C P V+ G + + C+ G +L GS+ + C W+ PP
Sbjct: 233 TCEKITCRKPDVSHGEMVSGFGPIYNYKDTIVFKCQKGFVLRGSSVIHCDADSKWNPSPP 292
Query: 523 SCKYVNC-GTPTIHKGSFVLINGTT-----TYGSIAQFTCEPDYWLNGAE--ELVCNRDG 574
+C+ +C P I S+ T G++ ++ C P Y E ++C ++
Sbjct: 293 ACEPNSCINLPDIPHASWETYPRPTKEDVYVVGTVLRYRCHPGYKPTTDEPTTVICQKNL 352
Query: 575 KWSYDIPSCELTSCPEPEVPSGGYMEAFD--------YYVHSTINFHCEAGHKLIGEPNL 626
+W+ CE CPEP++ +G + Y+ I+F C + +
Sbjct: 353 RWT-PYQGCEALCCPEPKLNNGEITQHRKSRPANHCVYFYGDEISFSCHETSRF----SA 407
Query: 627 VCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRR 686
+CQ DG WS +P+C I C P + +G + + + I Y C Y LVG +
Sbjct: 408 ICQGDGTWSPRTPSCGDI-CNFPPKIAHGHYKQSSSYSFFKEEIIYECDKGYILVGQAKL 466
Query: 687 TCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIG 746
+C+ WS +P+C+ + C P + V G R S ++D Y
Sbjct: 467 SCSYS-HWSAPAPQCKAL-CRKPEL-------VNG----------RLSVDKD---QYVEP 504
Query: 747 ALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQY 782
V +C+ GY V+G TC N W P C++
Sbjct: 505 ENVTIQCDSGYGVVGPQSITCSGNRTWYPEVPKCEW 540
Score = 128 bits (308), Expect = 1e-28
Identities = 120/460 (26%), Positives = 176/460 (38%), Gaps = 51/460 (11%)
Query: 528 NCGTP-TIHKGSFVLINGTTTY---GSIAQFTCEPDYWLN-GAEELVCNRDGKWSYDIPS 582
NCG P T+ + + I T T G+ ++TC P Y + + L CN DG+W Y+
Sbjct: 49 NCGPPPTLSFAAPMDITLTETRFKTGTTLKYTCLPGYVRSHSTQTLTCNSDGEWVYNT-F 107
Query: 583 CELTSCPEPEVPSGGYMEA-FDYYVHSTINFHCEAGHKLIGEPNLVCQ-QDGE--WSGDS 638
C C P G +E D S I F C G LIG C+ QD WS
Sbjct: 108 CIYKRCRHPGELRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRGVGWSHPL 167
Query: 639 PTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQ----W 694
P CE + C P + G G + YSC + L+G +CT E + W
Sbjct: 168 PQCEIVKCKPPPDIRNGRHSGEENFYAYGFSVTYSCDPRFSLLGHASISCTVENETIGVW 227
Query: 695 SDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCE 754
S P CE+I C P D SHG + G Y + ++C+
Sbjct: 228 RPSPPTCEKITCRKP-------------DVSHGEMV------SGFGPIYNYKDTIVFKCQ 268
Query: 755 KGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGK---VTLPSNATFY--GATA 809
KG+ + G S+ C+ + +W+ + P C+ C N I + P+ Y G
Sbjct: 269 KGFVLRGSSVIHCDADSKWNPSPPACEPNSCINLPDIPHASWETYPRPTKEDVYVVGTVL 328
Query: 810 FYQCDENWE--LEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSI 867
Y+C ++ + +CQ+N W+ C+ + CP+P K +G +
Sbjct: 329 RYRCHPGYKPTTDEPTTVICQKNLRWTPYQG-CEALCCPEP----KLNNGEITQHRKSRP 383
Query: 868 GGEAHYQCERGYNLKGHQT----RTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNG 923
Y + H+T C G W+ P C I C P I +G S+
Sbjct: 384 ANHCVYFYGDEISFSCHETSRFSAICQGDGTWSPRTPSCGDI-CNFPPKIAHGHYKQSSS 442
Query: 924 STLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
+ F + Y C Y VG C WS P C+
Sbjct: 443 YSFFKEEIIYECDKGYILVGQAKLSC-SYSHWSAPAPQCK 481
Score = 91.5 bits (217), Expect = 2e-17
Identities = 75/311 (24%), Positives = 119/311 (38%), Gaps = 27/311 (8%)
Query: 352 TCGSPDKLLNTTI--LGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYV 409
TC PD + G Y+ IV+KC +G +L G HC D W+ +PP+C+
Sbjct: 238 TCRKPDVSHGEMVSGFGPIYNYKDTIVFKCQKGFVLRGSSVIHCDADSKWNPSPPACEPN 297
Query: 410 NCGGLTPIEDGDVALIDNRTTH-----GARALYSCRENFTLVGNPERT--CGDEGIWDGE 462
+C L I T G Y C + + T C W
Sbjct: 298 SCINLPDIPHASWETYPRPTKEDVYVVGTVLRYRCHPGYKPTTDEPTTVICQKNLRWT-P 356
Query: 463 APRCLFDWCPDPPAVSNASVTVNGHKA---------GSLASYTCENGHILSGSTSVTCTL 513
C CP+ P ++N +T + G S++C + S C
Sbjct: 357 YQGCEALCCPE-PKLNNGEITQHRKSRPANHCVYFYGDEISFSCHE----TSRFSAICQG 411
Query: 514 GGAWSGVPPSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRD 573
G WS PSC + P I G + + + + + C+ Y L G +L C+
Sbjct: 412 DGTWSPRTPSCGDICNFPPKIAHGHYKQSSSYSFFKEEIIYECDKGYILVGQAKLSCSY- 470
Query: 574 GKWSYDIPSCELTSCPEPEVPSGGYMEAFDYYVH-STINFHCEAGHKLIGEPNLVCQQDG 632
WS P C+ C +PE+ +G D YV + C++G+ ++G ++ C +
Sbjct: 471 SHWSAPAPQCK-ALCRKPELVNGRLSVDKDQYVEPENVTIQCDSGYGVVGPQSITCSGNR 529
Query: 633 EWSGDSPTCEY 643
W + P CE+
Sbjct: 530 TWYPEVPKCEW 540
Score = 34.3 bits (75), Expect = 2.4
Identities = 25/72 (34%), Positives = 29/72 (40%), Gaps = 8/72 (11%)
Query: 1 RCGHPAVPPNARVSIPNEENIVA-GTIAVYECDEGYELFGARQRECTLR----GDWTLEP 55
+C P N R S EEN A G Y CD + L G CT+ G W P
Sbjct: 174 KCKPPPDIRNGRHS--GEENFYAYGFSVTYSCDPRFSLLGHASISCTVENETIGVWRPSP 231
Query: 56 PFCGTNVAFRKP 67
P C + RKP
Sbjct: 232 PTC-EKITCRKP 242
>AL445493-8|CAH70782.1| 597|Homo sapiens complement component 4
binding protein, alpha protein.
Length = 597
Score = 187 bits (455), Expect = 2e-46
Identities = 147/527 (27%), Positives = 231/527 (43%), Gaps = 55/527 (10%)
Query: 471 CPDPPAVSNAS-----VTVNGHKAGSLASYTCENGHILSGST-SVTCTLGGAWSGVPPSC 524
C PP +S A+ +T K G+ YTC G++ S ST ++TC G W C
Sbjct: 50 CGPPPTLSFAAPMDITLTETRFKTGTTLKYTCLPGYVRSHSTQTLTCNSDGEWV-YNTFC 108
Query: 525 KYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVC---NRDGKWSYDIP 581
Y C P + V I ++GS +F+C ++L G+ C +R WS+ +P
Sbjct: 109 IYKRCRHPGELRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRGVGWSHPLP 168
Query: 582 SCELTSC-PEPEVPSGGYMEAFDYYVHS-TINFHCEAGHKLIGEPNLVCQQDGE----WS 635
CE+ C P P++ +G + ++Y + ++ + C+ L+G ++ C + E W
Sbjct: 169 QCEIVKCKPPPDIRNGRHSGEENFYAYGFSVTYSCDPRFSLLGHASISCTVENETIGVWR 228
Query: 636 GDSPTCEYIDCGKLPTLPYGTMELLNGTTH-LGSVIQYSCTTNYRLVGPVRRTCTEEFQW 694
PTCE I C K P + +G M G + I + C + L G C + +W
Sbjct: 229 PSPPTCEKITCRK-PDVSHGEMVSGFGPIYNYKDTIVFKCQKGFVLRGSSVIHCDADSKW 287
Query: 695 SDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCE 754
+ S P CE C +++ + T R + DV Y +G +++YRC
Sbjct: 288 NPSPPACEPNSC----------INLPDIPHASWETYPRPT-KEDV---YVVGTVLRYRCH 333
Query: 755 KGYKVIGESLST--CEDNGQWSGTTPTCQYVDCGNPGRIENGKVTL-----PSN--ATFY 805
GYK + +T C+ N +W+ C+ + C P ++ NG++T P+N FY
Sbjct: 334 PGYKPTTDEPTTVICQKNLRWT-PYQGCEALCCPEP-KLNNGEITQHRKSRPANHCVYFY 391
Query: 806 GATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTL 865
G + C E + CQ +GTWS P C +I C P K G +S+
Sbjct: 392 GDEISFSCHETSRFSAI----CQGDGTWSPRTPSCGDI-CNFPP---KIAHGHYKQSSSY 443
Query: 866 SI-GGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGS 924
S E Y+C++GY L G +C S W+ P C + CR P + NG++ +
Sbjct: 444 SFFKEEIIYECDKGYILVGQAKLSC-SYSHWSAPAPQCKAL-CRKP-ELVNGRLSVDKDQ 500
Query: 925 TLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCELATNEAVD 971
+ +V C S Y VGP C + W E P CE T E +
Sbjct: 501 YVEPENVTIQCDSGYGVVGPQSITCSGNRTWYPEVPKCEWETPEGCE 547
Score = 173 bits (421), Expect = 3e-42
Identities = 131/502 (26%), Positives = 205/502 (40%), Gaps = 46/502 (9%)
Query: 421 DVALIDNRTTHGARALYSCRENFTLVGNPER-TCGDEGIWDGEAPRCLFDWCPDPPAVSN 479
D+ L + R G Y+C + + + TC +G W C++ C P + N
Sbjct: 63 DITLTETRFKTGTTLKYTCLPGYVRSHSTQTLTCNSDGEWVYNT-FCIYKRCRHPGELRN 121
Query: 480 ASVTVNGHKA-GSLASYTCENGHILSGSTSVTCTL---GGAWSGVPPSCKYVNCGTPT-I 534
V + + GS ++C G L GST+ C + G WS P C+ V C P I
Sbjct: 122 GQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRGVGWSHPLPQCEIVKCKPPPDI 181
Query: 535 HKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRD----GKWSYDIPSCELTSCPE 590
G YG ++C+P + L G + C + G W P+CE +C +
Sbjct: 182 RNGRHSGEENFYAYGFSVTYSCDPRFSLLGHASISCTVENETIGVWRPSPPTCEKITCRK 241
Query: 591 PEVPSGGYMEAFD--YYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGK 648
P+V G + F Y TI F C+ G L G + C D +W+ P CE C
Sbjct: 242 PDVSHGEMVSGFGPIYNYKDTIVFKCQKGFVLRGSSVIHCDADSKWNPSPPACEPNSCIN 301
Query: 649 LPTLPYGTMELLNGTTH-----LGSVIQYSCTTNYRLV--GPVRRTCTEEFQWSDSSPRC 701
LP +P+ + E T +G+V++Y C Y+ P C + +W+ C
Sbjct: 302 LPDIPHASWETYPRPTKEDVYVVGTVLRYRCHPGYKPTTDEPTTVICQKNLRWTPYQ-GC 360
Query: 702 EEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIG 761
E + C +P + I H R +++ Y G + + C +
Sbjct: 361 EALCCPEPKLNNGEITQ---------HRKSRPANH----CVYFYGDEISFSCHE----TS 403
Query: 762 ESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEG 821
+ C+ +G WS TP+C + C P +I +G S+ +F+ Y+CD+ + L G
Sbjct: 404 RFSAICQGDGTWSPRTPSCGDI-CNFPPKIAHGHYKQSSSYSFFKEEIIYECDKGYILVG 462
Query: 822 VIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGE-AHYQCERGYN 880
+ C + WS P CK + C P + +G L V + E QC+ GY
Sbjct: 463 QAKLSCSYS-HWSAPAPQCKAL-CRKP----ELVNGRLSVDKDQYVEPENVTIQCDSGYG 516
Query: 881 LKGHQTRTCISKGQWNGTVPVC 902
+ G Q+ TC W VP C
Sbjct: 517 VVGPQSITCSGNRTWYPEVPKC 538
Score = 148 bits (358), Expect = 1e-34
Identities = 117/456 (25%), Positives = 189/456 (41%), Gaps = 54/456 (11%)
Query: 353 CGSPDKLLNTTI-LGNDYDVGSRIVYKCPEGHMLLGDKSRHCK---KDGFWSGAPPSCKY 408
C P +L N + + D GS+I + C EG L+G + C+ + WS P C+
Sbjct: 113 CRHPGELRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRGVGWSHPLPQCEI 172
Query: 409 VNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDE----GIWDGEAP 464
V C I +G + +N +G YSC F+L+G+ +C E G+W P
Sbjct: 173 VKCKPPPDIRNGRHSGEENFYAYGFSVTYSCDPRFSLLGHASISCTVENETIGVWRPSPP 232
Query: 465 RCLFDWCPDPPAVSNASVTVNG--HKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPP 522
C C P V+ G + + C+ G +L GS+ + C W+ PP
Sbjct: 233 TCEKITCRKPDVSHGEMVSGFGPIYNYKDTIVFKCQKGFVLRGSSVIHCDADSKWNPSPP 292
Query: 523 SCKYVNC-GTPTIHKGSFVLINGTT-----TYGSIAQFTCEPDYWLNGAE--ELVCNRDG 574
+C+ +C P I S+ T G++ ++ C P Y E ++C ++
Sbjct: 293 ACEPNSCINLPDIPHASWETYPRPTKEDVYVVGTVLRYRCHPGYKPTTDEPTTVICQKNL 352
Query: 575 KWSYDIPSCELTSCPEPEVPSGGYMEAFD--------YYVHSTINFHCEAGHKLIGEPNL 626
+W+ CE CPEP++ +G + Y+ I+F C + +
Sbjct: 353 RWT-PYQGCEALCCPEPKLNNGEITQHRKSRPANHCVYFYGDEISFSCHETSRF----SA 407
Query: 627 VCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRR 686
+CQ DG WS +P+C I C P + +G + + + I Y C Y LVG +
Sbjct: 408 ICQGDGTWSPRTPSCGDI-CNFPPKIAHGHYKQSSSYSFFKEEIIYECDKGYILVGQAKL 466
Query: 687 TCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIG 746
+C+ WS +P+C+ + C P + V G R S ++D Y
Sbjct: 467 SCSYS-HWSAPAPQCKAL-CRKPEL-------VNG----------RLSVDKD---QYVEP 504
Query: 747 ALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQY 782
V +C+ GY V+G TC N W P C++
Sbjct: 505 ENVTIQCDSGYGVVGPQSITCSGNRTWYPEVPKCEW 540
Score = 128 bits (308), Expect = 1e-28
Identities = 120/460 (26%), Positives = 176/460 (38%), Gaps = 51/460 (11%)
Query: 528 NCGTP-TIHKGSFVLINGTTTY---GSIAQFTCEPDYWLN-GAEELVCNRDGKWSYDIPS 582
NCG P T+ + + I T T G+ ++TC P Y + + L CN DG+W Y+
Sbjct: 49 NCGPPPTLSFAAPMDITLTETRFKTGTTLKYTCLPGYVRSHSTQTLTCNSDGEWVYNT-F 107
Query: 583 CELTSCPEPEVPSGGYMEA-FDYYVHSTINFHCEAGHKLIGEPNLVCQ-QDGE--WSGDS 638
C C P G +E D S I F C G LIG C+ QD WS
Sbjct: 108 CIYKRCRHPGELRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRGVGWSHPL 167
Query: 639 PTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQ----W 694
P CE + C P + G G + YSC + L+G +CT E + W
Sbjct: 168 PQCEIVKCKPPPDIRNGRHSGEENFYAYGFSVTYSCDPRFSLLGHASISCTVENETIGVW 227
Query: 695 SDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCE 754
S P CE+I C P D SHG + G Y + ++C+
Sbjct: 228 RPSPPTCEKITCRKP-------------DVSHGEMV------SGFGPIYNYKDTIVFKCQ 268
Query: 755 KGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGK---VTLPSNATFY--GATA 809
KG+ + G S+ C+ + +W+ + P C+ C N I + P+ Y G
Sbjct: 269 KGFVLRGSSVIHCDADSKWNPSPPACEPNSCINLPDIPHASWETYPRPTKEDVYVVGTVL 328
Query: 810 FYQCDENWE--LEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSI 867
Y+C ++ + +CQ+N W+ C+ + CP+P K +G +
Sbjct: 329 RYRCHPGYKPTTDEPTTVICQKNLRWTPYQG-CEALCCPEP----KLNNGEITQHRKSRP 383
Query: 868 GGEAHYQCERGYNLKGHQT----RTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNG 923
Y + H+T C G W+ P C I C P I +G S+
Sbjct: 384 ANHCVYFYGDEISFSCHETSRFSAICQGDGTWSPRTPSCGDI-CNFPPKIAHGHYKQSSS 442
Query: 924 STLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
+ F + Y C Y VG C WS P C+
Sbjct: 443 YSFFKEEIIYECDKGYILVGQAKLSC-SYSHWSAPAPQCK 481
Score = 91.5 bits (217), Expect = 2e-17
Identities = 75/311 (24%), Positives = 119/311 (38%), Gaps = 27/311 (8%)
Query: 352 TCGSPDKLLNTTI--LGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYV 409
TC PD + G Y+ IV+KC +G +L G HC D W+ +PP+C+
Sbjct: 238 TCRKPDVSHGEMVSGFGPIYNYKDTIVFKCQKGFVLRGSSVIHCDADSKWNPSPPACEPN 297
Query: 410 NCGGLTPIEDGDVALIDNRTTH-----GARALYSCRENFTLVGNPERT--CGDEGIWDGE 462
+C L I T G Y C + + T C W
Sbjct: 298 SCINLPDIPHASWETYPRPTKEDVYVVGTVLRYRCHPGYKPTTDEPTTVICQKNLRWT-P 356
Query: 463 APRCLFDWCPDPPAVSNASVTVNGHKA---------GSLASYTCENGHILSGSTSVTCTL 513
C CP+ P ++N +T + G S++C + S C
Sbjct: 357 YQGCEALCCPE-PKLNNGEITQHRKSRPANHCVYFYGDEISFSCHE----TSRFSAICQG 411
Query: 514 GGAWSGVPPSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRD 573
G WS PSC + P I G + + + + + C+ Y L G +L C+
Sbjct: 412 DGTWSPRTPSCGDICNFPPKIAHGHYKQSSSYSFFKEEIIYECDKGYILVGQAKLSCSY- 470
Query: 574 GKWSYDIPSCELTSCPEPEVPSGGYMEAFDYYVH-STINFHCEAGHKLIGEPNLVCQQDG 632
WS P C+ C +PE+ +G D YV + C++G+ ++G ++ C +
Sbjct: 471 SHWSAPAPQCK-ALCRKPELVNGRLSVDKDQYVEPENVTIQCDSGYGVVGPQSITCSGNR 529
Query: 633 EWSGDSPTCEY 643
W + P CE+
Sbjct: 530 TWYPEVPKCEW 540
Score = 34.3 bits (75), Expect = 2.4
Identities = 25/72 (34%), Positives = 29/72 (40%), Gaps = 8/72 (11%)
Query: 1 RCGHPAVPPNARVSIPNEENIVA-GTIAVYECDEGYELFGARQRECTLR----GDWTLEP 55
+C P N R S EEN A G Y CD + L G CT+ G W P
Sbjct: 174 KCKPPPDIRNGRHS--GEENFYAYGFSVTYSCDPRFSLLGHASISCTVENETIGVWRPSP 231
Query: 56 PFCGTNVAFRKP 67
P C + RKP
Sbjct: 232 PTC-EKITCRKP 242
>Z99572-3|CAI23059.1| 644|Homo sapiens selectin P (granule membrane
protein 140kDa, antigen CD62) protein.
Length = 644
Score = 185 bits (451), Expect = 7e-46
Identities = 111/363 (30%), Positives = 162/363 (44%), Gaps = 28/363 (7%)
Query: 365 LGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVAL 424
LGN + S+ + C +G+ + G C G W+ PP C C L E G++
Sbjct: 217 LGN-FSFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQCLAAQCPPLKIPERGNMTC 275
Query: 425 IDNRTT--HGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASV 482
+ + H + +SC E F LVG C G+W AP C C D P + A V
Sbjct: 276 LHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASGVWTAPAPVCKALQCQDLPVPNEARV 335
Query: 483 TVNGHKAG-----SLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTI--H 535
+ H G S+ S+TC G +L G++ + C G W+ VPP C+ + C TP +
Sbjct: 336 NCS-HPFGAFRYQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPECQAIPC-TPLLSPQ 393
Query: 536 KGSFVLIN--GTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCE-LTSCPEPE 592
G+ + G+++Y S QF C+ Y L+G E L C R G+W+ P CE + S P P
Sbjct: 394 NGTMTCVQPLGSSSYKSTCQFICDEGYSLSGPERLDCTRSGRWTDSPPMCEGIASLPTPG 453
Query: 593 V-------PSGGYM----EAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTC 641
V P G M + ++T F C AG LIG+ L C+ G+W+ +P C
Sbjct: 454 VQCPALTTPGQGTMYCRHHPGTFGFNTTCYFGCNAGFTLIGDSTLSCRPSGQWTAVTPAC 513
Query: 642 EYIDCGKLPTLPYGTMELLN--GTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSP 699
+ C +L M N G GS+ + C L G + C E WS + P
Sbjct: 514 RAVKCSELHVNKPIAMNCSNLWGNFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVP 573
Query: 700 RCE 702
C+
Sbjct: 574 TCQ 576
Score = 163 bits (396), Expect = 3e-39
Identities = 146/576 (25%), Positives = 227/576 (39%), Gaps = 81/576 (14%)
Query: 236 SFDEARKQCQSHGGDLIHGFQGATSSFLTQELERRKAQLKTQLVWIGAQKEPGLTSRTWQ 295
S++ +RK CQ+ DL+ +L + L + WIG +K ++TW
Sbjct: 52 SWNISRKYCQNRYTDLVAIQNKNEIDYLNKVLP-----YYSSYYWIGIRKN----NKTWT 102
Query: 296 WVDGELV---SKPSWGKDQPNNYNGEQNCV---VLDGGRGWLWNDVGCNLDYLHWICQYL 349
WV + +W ++PNN ++CV + WND C L H +C
Sbjct: 103 WVGTKKALTNEAENWADNEPNNKRNNEDCVEIYIKSPSAPGKWNDEHC-LKKKHALCY-- 159
Query: 350 PPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYV 409
T D ++ + G +C E +G+ + C GF+ P C+YV
Sbjct: 160 --TASCQD--MSCSKQG-----------ECLE---TIGNYTCSCYP-GFYG---PECEYV 197
Query: 410 N-CGGLTPIEDGDVALID--NRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRC 466
CG L + + + ++ + C + + + G + C GIW + P+C
Sbjct: 198 RECGELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQC 257
Query: 467 LFDWCPDPPAVSNASVT-VNGHKA---GSLASYTCENGHILSGSTSVTCTLGGAWSGVPP 522
L CP ++T ++ KA S S++CE G L G V CT G W+ P
Sbjct: 258 LAAQCPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASGVWTAPAP 317
Query: 523 SCKYVNCGTPTIHKGSFVLIN---GTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYD 579
CK + C + + V + G Y S+ FTC L GA L C G W+
Sbjct: 318 VCKALQCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLATGNWNSV 377
Query: 580 IPSCELTSCPEPEVPSGGYMEAFDYY----VHSTINFHCEAGHKLIGEPNLVCQQDGEWS 635
P C+ C P G M ST F C+ G+ L G L C + G W+
Sbjct: 378 PPECQAIPCTPLLSPQNGTMTCVQPLGSSSYKSTCQFICDEGYSLSGPERLDCTRSGRWT 437
Query: 636 GDSPTCEYI--------DCGKLPTLPYGTMELLN--GTTHLGSVIQYSCTTNYRLVGPVR 685
P CE I C L T GTM + GT + + C + L+G
Sbjct: 438 DSPPMCEGIASLPTPGVQCPALTTPGQGTMYCRHHPGTFGFNTTCYFGCNAGFTLIGDST 497
Query: 686 RTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRI 745
+C QW+ +P C ++CS+ + K I N + +
Sbjct: 498 LSCRPSGQWTAVTPACRAVKCSE-LHVNKPIAMNCSN----------------LWGNFSY 540
Query: 746 GALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQ 781
G++ + C +G + G + + C++NG WS T PTCQ
Sbjct: 541 GSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTCQ 576
Score = 157 bits (382), Expect = 2e-37
Identities = 107/402 (26%), Positives = 166/402 (41%), Gaps = 36/402 (8%)
Query: 581 PSCE-LTSCPEPEVPSGGYMEAF----DYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWS 635
P CE + C E E+P M ++ +S +FHC G+++ G L C G W+
Sbjct: 192 PECEYVRECGELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPSKLECLASGIWT 251
Query: 636 GDSPTCEYIDCGKLPTLPYGTMELLNGTTHLG--SVIQYSCTTNYRLVGPVRRTCTEEFQ 693
P C C L G M L+ S +SC + LVGP CT
Sbjct: 252 NKPPQCLAAQCPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASGV 311
Query: 694 WSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRC 753
W+ +P C+ ++C D V ++ V+ SH +R ++ + C
Sbjct: 312 WTAPAPVCKALQCQDLPVPNEARVNC-----SHPF------------GAFRYQSVCSFTC 354
Query: 754 EKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTL--PSNATFYGATAFY 811
+G ++G S+ C G W+ P CQ + C +NG +T P ++ Y +T +
Sbjct: 355 NEGLLLVGASVLQCLATGNWNSVPPECQAIPCTPLLSPQNGTMTCVQPLGSSSYKSTCQF 414
Query: 812 QCDENWELEGVIRRMCQENGTWSLEPPICKEI-TCPDPSAQIKA----GSGLLVV---TS 863
CDE + L G R C +G W+ PP+C+ I + P P Q A G G +
Sbjct: 415 ICDEGYSLSGPERLDCTRSGRWTDSPPMCEGIASLPTPGVQCPALTTPGQGTMYCRHHPG 474
Query: 864 TLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISN- 922
T ++ C G+ L G T +C GQW P C + C + + SN
Sbjct: 475 TFGFNTTCYFGCNAGFTLIGDSTLSCRPSGQWTAVTPACRAVKCSELHVNKPIAMNCSNL 534
Query: 923 -GSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
G+ +GS ++CL G C ++G WS P+C+
Sbjct: 535 WGNFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTCQ 576
Score = 40.7 bits (91), Expect = 0.028
Identities = 15/28 (53%), Positives = 17/28 (60%)
Query: 31 CDEGYELFGARQRECTLRGDWTLEPPFC 58
CDEGY L G + +CT G WT PP C
Sbjct: 416 CDEGYSLSGPERLDCTRSGRWTDSPPMC 443
Score = 35.9 bits (79), Expect = 0.79
Identities = 16/58 (27%), Positives = 28/58 (48%), Gaps = 1/58 (1%)
Query: 2 CGHPAVPPNARVSIPNE-ENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
CG +P + ++ + N + + C +GY++ G + EC G WT +PP C
Sbjct: 200 CGELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQC 257
Score = 34.7 bits (76), Expect = 1.8
Identities = 18/59 (30%), Positives = 27/59 (45%), Gaps = 1/59 (1%)
Query: 1 RCGHPAVPPNARVSIPNEENIVA-GTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
+C VP ARV+ + ++ + C+EG L GA +C G+W PP C
Sbjct: 323 QCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPEC 381
Score = 34.3 bits (75), Expect = 2.4
Identities = 12/30 (40%), Positives = 16/30 (53%)
Query: 29 YECDEGYELFGARQRECTLRGDWTLEPPFC 58
+ C+EG+ L G +CT G WT P C
Sbjct: 290 FSCEEGFALVGPEVVQCTASGVWTAPAPVC 319
Score = 32.3 bits (70), Expect = 9.7
Identities = 20/62 (32%), Positives = 27/62 (43%), Gaps = 3/62 (4%)
Query: 20 NIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTNVAFRKPANQSTTVRGGAA 79
N G+I + C EG L G+ Q C G W+ P C A ++ T GGA
Sbjct: 537 NFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTC---QAGPLTIQEALTYFGGAV 593
Query: 80 AN 81
A+
Sbjct: 594 AS 595
>AL022146-3|CAI22754.1| 644|Homo sapiens selectin P (granule
membrane protein 140kDa, antigen CD62) protein.
Length = 644
Score = 185 bits (451), Expect = 7e-46
Identities = 111/363 (30%), Positives = 162/363 (44%), Gaps = 28/363 (7%)
Query: 365 LGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVAL 424
LGN + S+ + C +G+ + G C G W+ PP C C L E G++
Sbjct: 217 LGN-FSFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQCLAAQCPPLKIPERGNMTC 275
Query: 425 IDNRTT--HGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASV 482
+ + H + +SC E F LVG C G+W AP C C D P + A V
Sbjct: 276 LHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASGVWTAPAPVCKALQCQDLPVPNEARV 335
Query: 483 TVNGHKAG-----SLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTI--H 535
+ H G S+ S+TC G +L G++ + C G W+ VPP C+ + C TP +
Sbjct: 336 NCS-HPFGAFRYQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPECQAIPC-TPLLSPQ 393
Query: 536 KGSFVLIN--GTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCE-LTSCPEPE 592
G+ + G+++Y S QF C+ Y L+G E L C R G+W+ P CE + S P P
Sbjct: 394 NGTMTCVQPLGSSSYKSTCQFICDEGYSLSGPERLDCTRSGRWTDSPPMCEGIASLPTPG 453
Query: 593 V-------PSGGYM----EAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTC 641
V P G M + ++T F C AG LIG+ L C+ G+W+ +P C
Sbjct: 454 VQCPALTTPGQGTMYCRHHPGTFGFNTTCYFGCNAGFTLIGDSTLSCRPSGQWTAVTPAC 513
Query: 642 EYIDCGKLPTLPYGTMELLN--GTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSP 699
+ C +L M N G GS+ + C L G + C E WS + P
Sbjct: 514 RAVKCSELHVNKPIAMNCSNLWGNFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVP 573
Query: 700 RCE 702
C+
Sbjct: 574 TCQ 576
Score = 163 bits (396), Expect = 3e-39
Identities = 146/576 (25%), Positives = 227/576 (39%), Gaps = 81/576 (14%)
Query: 236 SFDEARKQCQSHGGDLIHGFQGATSSFLTQELERRKAQLKTQLVWIGAQKEPGLTSRTWQ 295
S++ +RK CQ+ DL+ +L + L + WIG +K ++TW
Sbjct: 52 SWNISRKYCQNRYTDLVAIQNKNEIDYLNKVLP-----YYSSYYWIGIRKN----NKTWT 102
Query: 296 WVDGELV---SKPSWGKDQPNNYNGEQNCV---VLDGGRGWLWNDVGCNLDYLHWICQYL 349
WV + +W ++PNN ++CV + WND C L H +C
Sbjct: 103 WVGTKKALTNEAENWADNEPNNKRNNEDCVEIYIKSPSAPGKWNDEHC-LKKKHALCY-- 159
Query: 350 PPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYV 409
T D ++ + G +C E +G+ + C GF+ P C+YV
Sbjct: 160 --TASCQD--MSCSKQG-----------ECLE---TIGNYTCSCYP-GFYG---PECEYV 197
Query: 410 N-CGGLTPIEDGDVALID--NRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRC 466
CG L + + + ++ + C + + + G + C GIW + P+C
Sbjct: 198 RECGELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQC 257
Query: 467 LFDWCPDPPAVSNASVT-VNGHKA---GSLASYTCENGHILSGSTSVTCTLGGAWSGVPP 522
L CP ++T ++ KA S S++CE G L G V CT G W+ P
Sbjct: 258 LAAQCPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASGVWTAPAP 317
Query: 523 SCKYVNCGTPTIHKGSFVLIN---GTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYD 579
CK + C + + V + G Y S+ FTC L GA L C G W+
Sbjct: 318 VCKALQCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLATGNWNSV 377
Query: 580 IPSCELTSCPEPEVPSGGYMEAFDYY----VHSTINFHCEAGHKLIGEPNLVCQQDGEWS 635
P C+ C P G M ST F C+ G+ L G L C + G W+
Sbjct: 378 PPECQAIPCTPLLSPQNGTMTCVQPLGSSSYKSTCQFICDEGYSLSGPERLDCTRSGRWT 437
Query: 636 GDSPTCEYI--------DCGKLPTLPYGTMELLN--GTTHLGSVIQYSCTTNYRLVGPVR 685
P CE I C L T GTM + GT + + C + L+G
Sbjct: 438 DSPPMCEGIASLPTPGVQCPALTTPGQGTMYCRHHPGTFGFNTTCYFGCNAGFTLIGDST 497
Query: 686 RTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRI 745
+C QW+ +P C ++CS+ + K I N + +
Sbjct: 498 LSCRPSGQWTAVTPACRAVKCSE-LHVNKPIAMNCSN----------------LWGNFSY 540
Query: 746 GALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQ 781
G++ + C +G + G + + C++NG WS T PTCQ
Sbjct: 541 GSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTCQ 576
Score = 157 bits (382), Expect = 2e-37
Identities = 107/402 (26%), Positives = 166/402 (41%), Gaps = 36/402 (8%)
Query: 581 PSCE-LTSCPEPEVPSGGYMEAF----DYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWS 635
P CE + C E E+P M ++ +S +FHC G+++ G L C G W+
Sbjct: 192 PECEYVRECGELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPSKLECLASGIWT 251
Query: 636 GDSPTCEYIDCGKLPTLPYGTMELLNGTTHLG--SVIQYSCTTNYRLVGPVRRTCTEEFQ 693
P C C L G M L+ S +SC + LVGP CT
Sbjct: 252 NKPPQCLAAQCPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASGV 311
Query: 694 WSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRC 753
W+ +P C+ ++C D V ++ V+ SH +R ++ + C
Sbjct: 312 WTAPAPVCKALQCQDLPVPNEARVNC-----SHPF------------GAFRYQSVCSFTC 354
Query: 754 EKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTL--PSNATFYGATAFY 811
+G ++G S+ C G W+ P CQ + C +NG +T P ++ Y +T +
Sbjct: 355 NEGLLLVGASVLQCLATGNWNSVPPECQAIPCTPLLSPQNGTMTCVQPLGSSSYKSTCQF 414
Query: 812 QCDENWELEGVIRRMCQENGTWSLEPPICKEI-TCPDPSAQIKA----GSGLLVV---TS 863
CDE + L G R C +G W+ PP+C+ I + P P Q A G G +
Sbjct: 415 ICDEGYSLSGPERLDCTRSGRWTDSPPMCEGIASLPTPGVQCPALTTPGQGTMYCRHHPG 474
Query: 864 TLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISN- 922
T ++ C G+ L G T +C GQW P C + C + + SN
Sbjct: 475 TFGFNTTCYFGCNAGFTLIGDSTLSCRPSGQWTAVTPACRAVKCSELHVNKPIAMNCSNL 534
Query: 923 -GSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
G+ +GS ++CL G C ++G WS P+C+
Sbjct: 535 WGNFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTCQ 576
Score = 40.7 bits (91), Expect = 0.028
Identities = 15/28 (53%), Positives = 17/28 (60%)
Query: 31 CDEGYELFGARQRECTLRGDWTLEPPFC 58
CDEGY L G + +CT G WT PP C
Sbjct: 416 CDEGYSLSGPERLDCTRSGRWTDSPPMC 443
Score = 35.9 bits (79), Expect = 0.79
Identities = 16/58 (27%), Positives = 28/58 (48%), Gaps = 1/58 (1%)
Query: 2 CGHPAVPPNARVSIPNE-ENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
CG +P + ++ + N + + C +GY++ G + EC G WT +PP C
Sbjct: 200 CGELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQC 257
Score = 34.7 bits (76), Expect = 1.8
Identities = 18/59 (30%), Positives = 27/59 (45%), Gaps = 1/59 (1%)
Query: 1 RCGHPAVPPNARVSIPNEENIVA-GTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
+C VP ARV+ + ++ + C+EG L GA +C G+W PP C
Sbjct: 323 QCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPEC 381
Score = 34.3 bits (75), Expect = 2.4
Identities = 12/30 (40%), Positives = 16/30 (53%)
Query: 29 YECDEGYELFGARQRECTLRGDWTLEPPFC 58
+ C+EG+ L G +CT G WT P C
Sbjct: 290 FSCEEGFALVGPEVVQCTASGVWTAPAPVC 319
Score = 32.3 bits (70), Expect = 9.7
Identities = 20/62 (32%), Positives = 27/62 (43%), Gaps = 3/62 (4%)
Query: 20 NIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTNVAFRKPANQSTTVRGGAA 79
N G+I + C EG L G+ Q C G W+ P C A ++ T GGA
Sbjct: 537 NFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTC---QAGPLTIQEALTYFGGAV 593
Query: 80 AN 81
A+
Sbjct: 594 AS 595
>X14362-1|CAA32541.1| 559|Homo sapiens protein ( Human CR1 mRNA for
C3b/C4b receptor secreted form. ).
Length = 559
Score = 185 bits (450), Expect = 9e-46
Identities = 143/547 (26%), Positives = 220/547 (40%), Gaps = 60/547 (10%)
Query: 368 DYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDN 427
++ +G+ + Y+C G+ S C K+ W+GA C+ +C +G V +I
Sbjct: 37 EFPIGTYLNYECRPGYSGR-PFSIICLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKG 95
Query: 428 RTTHGARALYSCRENFTLVGNPERTC---GDEGIWDGEAPRCLFDWCPDPPAVSNA---S 481
G++ YSC + + L+G+ TC GD IWD E P C C PP ++N S
Sbjct: 96 -IQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTITNGDFIS 154
Query: 482 VTVNGHKAGSLASYTCENG------HILSGSTSVTCTLG----GAWSGVPPSCKYVN-CG 530
GS+ +Y C G L G S+ CT G WSG P C N C
Sbjct: 155 TNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCT 214
Query: 531 TPTIHKGSFVLINGTT-TYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCP 589
P + G V N + + + +F C+P + + G + C KW ++PSC P
Sbjct: 215 PPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQP 274
Query: 590 EPEV--PSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCG 647
P+V + ++ + + CE G+ L G ++ C G+WS +PTCE C
Sbjct: 275 PPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCD 334
Query: 648 KLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCT---EEFQWSDSSPRCEEI 704
L LG+ + + C ++L G C E W+ S P CE+I
Sbjct: 335 DFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQI 394
Query: 705 RCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCE------KGYK 758
C P V N R G L + G V Y C+ +
Sbjct: 395 FCPSP--------PVIPNGRHTGKPL----------EVFPFGKAVNYTCDPHPDRGTSFD 436
Query: 759 VIGESLSTC----EDNGQWSGTTPTCQYV-DCGNPGRIENGKVTLPSNATFY--GATAFY 811
+IGES C + NG WS P C + C P K+ +NA+ + G + Y
Sbjct: 437 LIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKY 496
Query: 812 QCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEA 871
+C + C +N WS +CK +C P + +G++ V + + +G
Sbjct: 497 ECRPEY-YGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPV---NGMVHVITDIQVGSRI 552
Query: 872 HYQCERG 878
+Y C G
Sbjct: 553 NYSCTTG 559
Score = 171 bits (416), Expect = 1e-41
Identities = 143/535 (26%), Positives = 215/535 (40%), Gaps = 60/535 (11%)
Query: 437 YSCRENFTLVGNP-ERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASV-TVNGHKAGSLAS 494
Y CR ++ G P C +W G RC C +PP N V + G + GS
Sbjct: 46 YECRPGYS--GRPFSIICLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKGIQFGSQIK 103
Query: 495 YTCENGHILSGSTSVTCTLGG---AWSGVPPSCKYVNCGTP-TIHKGSFVLINGTTT-YG 549
Y+C G+ L GS+S TC + G W P C + CG P TI G F+ N YG
Sbjct: 104 YSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTITNGDFISTNRENFHYG 163
Query: 550 SIAQFTCEPD------YWLNGAEELVC--NRD--GKWSYDIPSCELTS-CPEPEVPSGGY 598
S+ + C P + L G + C N D G WS P C + + C P V +G
Sbjct: 164 SVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGIL 223
Query: 599 MEAFD--YYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGT 656
+ + ++ + F C+ G + G + CQ +W + P+C + C P + +
Sbjct: 224 VSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRV-CQPPPDVLHAE 282
Query: 657 MELLNGTTHL-GSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKS 715
+ G + YSC Y L G CT + WS ++P CE C D +
Sbjct: 283 RTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDFM----- 337
Query: 716 IVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQ--- 772
+G L + ++GA V + C++G+++ G S S C G
Sbjct: 338 ------GQLLNGRVLFPVN--------LQLGAKVDFVCDEGFQLKGSSASYCVLAGMESL 383
Query: 773 WSGTTPTCQYVDCGNPGRIENGKVT-LPSNATFYGATAFYQCDEN------WELEGVIRR 825
W+ + P C+ + C +P I NG+ T P +G Y CD + ++L G
Sbjct: 384 WNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTI 443
Query: 826 MC----QENGTWSLEPPICKEIT-CPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYN 880
C Q NG WS P C + C P + A S IG Y+C Y
Sbjct: 444 RCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYY 503
Query: 881 LKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYC 935
+ TC+ W+ VC C++P + NG + + + GS + Y C
Sbjct: 504 GRPFSI-TCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQV-GSRINYSC 556
Score = 169 bits (411), Expect = 5e-41
Identities = 135/509 (26%), Positives = 209/509 (41%), Gaps = 59/509 (11%)
Query: 490 GSLASYTCENGHILSGST-SVTCTLGGAWSGVPPSCKYVNCGTPTIHKGSFVLINGTTTY 548
G+ +Y C G+ SG S+ C W+G C+ +C P V + +
Sbjct: 41 GTYLNYECRPGY--SGRPFSIICLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKGIQF 98
Query: 549 GSIAQFTCEPDYWLNGAEELVCNRDGK---WSYDIPSCELTSCP-EPEVPSGGYMEAF-- 602
GS +++C Y L G+ C G W + P C+ C P + +G ++
Sbjct: 99 GSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTITNGDFISTNRE 158
Query: 603 DYYVHSTINFHCEAGH------KLIGEPNLVC----QQDGEWSGDSPTCEYIDCGKLPTL 652
+++ S + + C G +L+GEP++ C Q G WSG +P C + P +
Sbjct: 159 NFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNV 218
Query: 653 PYGTMELLNGTTH-LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIV 711
G + N + L V+++ C + + GP R C +W P C + C P
Sbjct: 219 ENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRV-CQPP-- 275
Query: 712 AEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNG 771
D H R DN + G V Y CE GY + G + C G
Sbjct: 276 ----------PDVLHAERTQRDKDN------FSPGQEVFYSCEPGYDLRGAASMRCTPQG 319
Query: 772 QWSGTTPTCQYVDCGN-PGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQEN 830
WS PTC+ C + G++ NG+V P N GA + CDE ++L+G C
Sbjct: 320 DWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQL-GAKVDFVCDEGFQLKGSSASYCVLA 378
Query: 831 GT---WSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCE----RG--YNL 881
G W+ P+C++I CP P I G G +Y C+ RG ++L
Sbjct: 379 GMESLWNSSVPVCEQIFCPSPPV-IPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDL 437
Query: 882 KGHQTRTCIS----KGQWNGTVPVC-IPIDCRSPGNIENGKIVISNGSTLF--GSSVEYY 934
G T C S G W+ P C I C++P + K+ ++ F G+S++Y
Sbjct: 438 IGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYE 497
Query: 935 CLSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
C +Y PF CLD+ WS + C+
Sbjct: 498 CRPEYYG-RPFSITCLDNLVWSSPKDVCK 525
Score = 162 bits (393), Expect = 7e-39
Identities = 136/500 (27%), Positives = 201/500 (40%), Gaps = 59/500 (11%)
Query: 352 TCGSPDKLLNTTI-LGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDG---FWSGAPPSCK 407
+C +P +N + + GS+I Y C +G+ L+G S C G W P C
Sbjct: 78 SCRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICD 137
Query: 408 YVNCGGLTPIEDGDVALIDNRTTH-GARALYSC------RENFTLVGNPERTC--GDE-- 456
+ CG I +GD + H G+ Y C R+ F LVG P C D+
Sbjct: 138 RIPCGLPPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQV 197
Query: 457 GIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGSL---ASYTCENGHILSGSTSVTCTL 513
GIW G AP+C+ PP V N + + SL + C+ G ++ G V C
Sbjct: 198 GIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQA 257
Query: 514 GGAWSGVPPSCKYVNCGTP--TIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCN 571
W PSC V C P +H + G ++CEP Y L GA + C
Sbjct: 258 LNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCT 316
Query: 572 RDGKWSYDIPSCELTSCPE--PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQ 629
G WS P+CE+ SC + ++ +G + + + + ++F C+ G +L G C
Sbjct: 317 PQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCV 376
Query: 630 QDGE---WSGDSPTCEYIDCGKLPTLPYG--TMELLNGTTHLGSVIQYSCT------TNY 678
G W+ P CE I C P +P G T + L G + Y+C T++
Sbjct: 377 LAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLE-VFPFGKAVNYTCDPHPDRGTSF 435
Query: 679 RLVGPVRRTCTEEFQ----WSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTS 734
L+G CT + Q WS +PRC + G+ ++ H L
Sbjct: 436 DLIGESTIRCTSDPQGNGVWSSPAPRC----------------GILGHCQAPDHFLFAKL 479
Query: 735 DNRDVGNTYRIGALVKYRCEKGYKVIGESLS-TCEDNGQWSGTTPTCQYVDCGNPGRIEN 793
+ + + IG +KY C Y G S TC DN WS C+ C P N
Sbjct: 480 KTQTNASDFPIGTSLKYECRPEY--YGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVN 537
Query: 794 GKVTLPSNATFYGATAFYQC 813
G V + ++ G+ Y C
Sbjct: 538 GMVHVITDIQ-VGSRINYSC 556
Score = 101 bits (243), Expect = 1e-20
Identities = 80/316 (25%), Positives = 124/316 (39%), Gaps = 42/316 (13%)
Query: 666 LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRS 725
+G+ + Y C Y P C + W+ + RC C +P +V V
Sbjct: 40 IGTYLNYECRPGYS-GRPFSIICLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKG--- 95
Query: 726 HGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTCQY 782
+ G+ +KY C KGY++IG S +TC +G W TP C
Sbjct: 96 -----------------IQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDR 138
Query: 783 VDCGNPGRIENGKVTLPSNATF-YGATAFYQCDEN------WELEGVIRRMCQEN----G 831
+ CG P I NG + F YG+ Y+C+ +EL G C N G
Sbjct: 139 IPCGLPPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVG 198
Query: 832 TWSLEPPICKEITCPDPSAQIKAGSGLLVV--TSTLSIGGEAHYQCERGYNLKGHQTRTC 889
WS P C P+ +G+LV S S+ ++C+ G+ +KG + C
Sbjct: 199 IWSGPAPQC---IIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKC 255
Query: 890 ISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLF-GSSVEYYCLSQYQRVGPFLRK 948
+ +W +P C + C+ P ++ + + + G V Y C Y G +
Sbjct: 256 QALNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMR 314
Query: 949 CLDDGRWSGEEPSCEL 964
C G WS P+CE+
Sbjct: 315 CTPQGDWSPAAPTCEV 330
Score = 96.3 bits (229), Expect = 5e-19
Identities = 74/237 (31%), Positives = 98/237 (41%), Gaps = 23/237 (9%)
Query: 743 YRIGALVKYRCEKGYKVIGESLST-CEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSN 801
+ IG + Y C GY G S C N W+G C+ C NP NG V +
Sbjct: 38 FPIGTYLNYECRPGYS--GRPFSIICLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKG 95
Query: 802 ATFYGATAFYQCDENWELEGVIRRMCQENG---TWSLEPPICKEITCPDPSAQIKAGSGL 858
F G+ Y C + + L G C +G W E PIC I C P I G +
Sbjct: 96 IQF-GSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPT-ITNGDFI 153
Query: 859 LVVTSTLSIGGEAHYQCERG------YNLKGHQTRTCISK----GQWNGTVPVC-IPIDC 907
G Y+C G + L G + C S G W+G P C IP C
Sbjct: 154 STNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKC 213
Query: 908 RSPGNIENGKIVISNGSTLFGSS--VEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
+P N+ENG I++S+ +LF + VE+ C + GP KC +W E PSC
Sbjct: 214 -TPPNVENG-ILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSC 268
Score = 93.9 bits (223), Expect = 3e-18
Identities = 84/358 (23%), Positives = 141/358 (39%), Gaps = 38/358 (10%)
Query: 349 LPPTCGSPDKLLNTTILGND---YDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPS 405
+P C +P + N ++ ++ + + + ++C G ++ G + C+ W PS
Sbjct: 209 IPNKC-TPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPS 267
Query: 406 CKYVNCGGLTPIEDGDVALID-NRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAP 464
C V C + + D + + G YSC + L G C +G W AP
Sbjct: 268 CSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAP 326
Query: 465 RCLFDWCPD-PPAVSNASVTVNGH-KAGSLASYTCENGHILSGSTSVTCTLGGA---WSG 519
C C D + N V + + G+ + C+ G L GS++ C L G W+
Sbjct: 327 TCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNS 386
Query: 520 VPPSCKYVNCGTPTI-----HKGSFVLINGTTTYGSIAQFTCEP------DYWLNGAEEL 568
P C+ + C +P + H G + + +G +TC+P + L G +
Sbjct: 387 SVPVCEQIFCPSPPVIPNGRHTGKPLEV---FPFGKAVNYTCDPHPDRGTSFDLIGESTI 443
Query: 569 VCNRD----GKWSYDIPSCELTS-CPEPE----VPSGGYMEAFDYYVHSTINFHCEAGHK 619
C D G WS P C + C P+ A D+ + +++ + C +
Sbjct: 444 RCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEY- 502
Query: 620 LIGEP-NLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTT 676
G P ++ C + WS C+ C K P P M + +GS I YSCTT
Sbjct: 503 -YGRPFSITCLDNLVWSSPKDVCKRKSC-KTPPDPVNGMVHVITDIQVGSRINYSCTT 558
Score = 42.3 bits (95), Expect = 0.009
Identities = 19/57 (33%), Positives = 28/57 (49%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C P +A + +++N G Y C+ GY+L GA CT +GDW+ P C
Sbjct: 272 CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTC 328
Score = 37.5 bits (83), Expect = 0.26
Identities = 20/60 (33%), Positives = 27/60 (45%), Gaps = 5/60 (8%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGD---WTLEPPFC 58
C +P P N V + + I G+ Y C +GY L G+ C + GD W E P C
Sbjct: 79 CRNPPDPVNGMVHVI--KGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPIC 136
>AL691452-6|CAI16728.1| 559|Homo sapiens complement component
(3b/4b) receptor 1 (Knops blood group) protein.
Length = 559
Score = 185 bits (450), Expect = 9e-46
Identities = 143/547 (26%), Positives = 220/547 (40%), Gaps = 60/547 (10%)
Query: 368 DYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDN 427
++ +G+ + Y+C G+ S C K+ W+GA C+ +C +G V +I
Sbjct: 37 EFPIGTYLNYECRPGYSGR-PFSIICLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKG 95
Query: 428 RTTHGARALYSCRENFTLVGNPERTC---GDEGIWDGEAPRCLFDWCPDPPAVSNA---S 481
G++ YSC + + L+G+ TC GD IWD E P C C PP ++N S
Sbjct: 96 -IQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTIANGDFIS 154
Query: 482 VTVNGHKAGSLASYTCENG------HILSGSTSVTCTLG----GAWSGVPPSCKYVN-CG 530
GS+ +Y C G L G S+ CT G WSG P C N C
Sbjct: 155 TNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCT 214
Query: 531 TPTIHKGSFVLINGTT-TYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCP 589
P + G V N + + + +F C+P + + G + C KW ++PSC P
Sbjct: 215 PPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQP 274
Query: 590 EPEV--PSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCG 647
P+V + ++ + + CE G+ L G ++ C G+WS +PTCE C
Sbjct: 275 PPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCD 334
Query: 648 KLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCT---EEFQWSDSSPRCEEI 704
L LG+ + + C ++L G C E W+ S P CE+I
Sbjct: 335 DFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQI 394
Query: 705 RCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCE------KGYK 758
C P V N R G L + G V Y C+ +
Sbjct: 395 FCPSP--------PVIPNGRHTGKPL----------EVFPFGKAVNYTCDPHPDRGTSFD 436
Query: 759 VIGESLSTC----EDNGQWSGTTPTCQYV-DCGNPGRIENGKVTLPSNATFY--GATAFY 811
+IGES C + NG WS P C + C P K+ +NA+ + G + Y
Sbjct: 437 LIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKY 496
Query: 812 QCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEA 871
+C + C +N WS +CK +C P + +G++ V + + +G
Sbjct: 497 ECRPEY-YGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPV---NGMVHVITDIQVGSRI 552
Query: 872 HYQCERG 878
+Y C G
Sbjct: 553 NYSCTTG 559
Score = 171 bits (416), Expect = 1e-41
Identities = 143/535 (26%), Positives = 215/535 (40%), Gaps = 60/535 (11%)
Query: 437 YSCRENFTLVGNP-ERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASV-TVNGHKAGSLAS 494
Y CR ++ G P C +W G RC C +PP N V + G + GS
Sbjct: 46 YECRPGYS--GRPFSIICLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKGIQFGSQIK 103
Query: 495 YTCENGHILSGSTSVTCTLGG---AWSGVPPSCKYVNCGTP-TIHKGSFVLINGTTT-YG 549
Y+C G+ L GS+S TC + G W P C + CG P TI G F+ N YG
Sbjct: 104 YSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTIANGDFISTNRENFHYG 163
Query: 550 SIAQFTCEPD------YWLNGAEELVC--NRD--GKWSYDIPSCELTS-CPEPEVPSGGY 598
S+ + C P + L G + C N D G WS P C + + C P V +G
Sbjct: 164 SVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGIL 223
Query: 599 MEAFD--YYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGT 656
+ + ++ + F C+ G + G + CQ +W + P+C + C P + +
Sbjct: 224 VSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRV-CQPPPDVLHAE 282
Query: 657 MELLNGTTHL-GSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKS 715
+ G + YSC Y L G CT + WS ++P CE C D +
Sbjct: 283 RTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDFM----- 337
Query: 716 IVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQ--- 772
+G L + ++GA V + C++G+++ G S S C G
Sbjct: 338 ------GQLLNGRVLFPVN--------LQLGAKVDFVCDEGFQLKGSSASYCVLAGMESL 383
Query: 773 WSGTTPTCQYVDCGNPGRIENGKVT-LPSNATFYGATAFYQCDEN------WELEGVIRR 825
W+ + P C+ + C +P I NG+ T P +G Y CD + ++L G
Sbjct: 384 WNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTI 443
Query: 826 MC----QENGTWSLEPPICKEIT-CPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYN 880
C Q NG WS P C + C P + A S IG Y+C Y
Sbjct: 444 RCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYY 503
Query: 881 LKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYC 935
+ TC+ W+ VC C++P + NG + + + GS + Y C
Sbjct: 504 GRPFSI-TCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQV-GSRINYSC 556
Score = 169 bits (411), Expect = 5e-41
Identities = 135/509 (26%), Positives = 209/509 (41%), Gaps = 59/509 (11%)
Query: 490 GSLASYTCENGHILSGST-SVTCTLGGAWSGVPPSCKYVNCGTPTIHKGSFVLINGTTTY 548
G+ +Y C G+ SG S+ C W+G C+ +C P V + +
Sbjct: 41 GTYLNYECRPGY--SGRPFSIICLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKGIQF 98
Query: 549 GSIAQFTCEPDYWLNGAEELVCNRDGK---WSYDIPSCELTSCP-EPEVPSGGYMEAF-- 602
GS +++C Y L G+ C G W + P C+ C P + +G ++
Sbjct: 99 GSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTIANGDFISTNRE 158
Query: 603 DYYVHSTINFHCEAGH------KLIGEPNLVC----QQDGEWSGDSPTCEYIDCGKLPTL 652
+++ S + + C G +L+GEP++ C Q G WSG +P C + P +
Sbjct: 159 NFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNV 218
Query: 653 PYGTMELLNGTTH-LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIV 711
G + N + L V+++ C + + GP R C +W P C + C P
Sbjct: 219 ENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRV-CQPP-- 275
Query: 712 AEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNG 771
D H R DN + G V Y CE GY + G + C G
Sbjct: 276 ----------PDVLHAERTQRDKDN------FSPGQEVFYSCEPGYDLRGAASMRCTPQG 319
Query: 772 QWSGTTPTCQYVDCGN-PGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQEN 830
WS PTC+ C + G++ NG+V P N GA + CDE ++L+G C
Sbjct: 320 DWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQL-GAKVDFVCDEGFQLKGSSASYCVLA 378
Query: 831 GT---WSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCE----RG--YNL 881
G W+ P+C++I CP P I G G +Y C+ RG ++L
Sbjct: 379 GMESLWNSSVPVCEQIFCPSPPV-IPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDL 437
Query: 882 KGHQTRTCIS----KGQWNGTVPVC-IPIDCRSPGNIENGKIVISNGSTLF--GSSVEYY 934
G T C S G W+ P C I C++P + K+ ++ F G+S++Y
Sbjct: 438 IGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYE 497
Query: 935 CLSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
C +Y PF CLD+ WS + C+
Sbjct: 498 CRPEYYG-RPFSITCLDNLVWSSPKDVCK 525
Score = 162 bits (393), Expect = 7e-39
Identities = 136/500 (27%), Positives = 201/500 (40%), Gaps = 59/500 (11%)
Query: 352 TCGSPDKLLNTTI-LGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDG---FWSGAPPSCK 407
+C +P +N + + GS+I Y C +G+ L+G S C G W P C
Sbjct: 78 SCRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICD 137
Query: 408 YVNCGGLTPIEDGDVALIDNRTTH-GARALYSC------RENFTLVGNPERTC--GDE-- 456
+ CG I +GD + H G+ Y C R+ F LVG P C D+
Sbjct: 138 RIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQV 197
Query: 457 GIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGSL---ASYTCENGHILSGSTSVTCTL 513
GIW G AP+C+ PP V N + + SL + C+ G ++ G V C
Sbjct: 198 GIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQA 257
Query: 514 GGAWSGVPPSCKYVNCGTP--TIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCN 571
W PSC V C P +H + G ++CEP Y L GA + C
Sbjct: 258 LNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCT 316
Query: 572 RDGKWSYDIPSCELTSCPE--PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQ 629
G WS P+CE+ SC + ++ +G + + + + ++F C+ G +L G C
Sbjct: 317 PQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCV 376
Query: 630 QDGE---WSGDSPTCEYIDCGKLPTLPYG--TMELLNGTTHLGSVIQYSCT------TNY 678
G W+ P CE I C P +P G T + L G + Y+C T++
Sbjct: 377 LAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLE-VFPFGKAVNYTCDPHPDRGTSF 435
Query: 679 RLVGPVRRTCTEEFQ----WSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTS 734
L+G CT + Q WS +PRC + G+ ++ H L
Sbjct: 436 DLIGESTIRCTSDPQGNGVWSSPAPRC----------------GILGHCQAPDHFLFAKL 479
Query: 735 DNRDVGNTYRIGALVKYRCEKGYKVIGESLS-TCEDNGQWSGTTPTCQYVDCGNPGRIEN 793
+ + + IG +KY C Y G S TC DN WS C+ C P N
Sbjct: 480 KTQTNASDFPIGTSLKYECRPEY--YGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVN 537
Query: 794 GKVTLPSNATFYGATAFYQC 813
G V + ++ G+ Y C
Sbjct: 538 GMVHVITDIQ-VGSRINYSC 556
Score = 101 bits (243), Expect = 1e-20
Identities = 80/316 (25%), Positives = 124/316 (39%), Gaps = 42/316 (13%)
Query: 666 LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRS 725
+G+ + Y C Y P C + W+ + RC C +P +V V
Sbjct: 40 IGTYLNYECRPGYS-GRPFSIICLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKG--- 95
Query: 726 HGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTCQY 782
+ G+ +KY C KGY++IG S +TC +G W TP C
Sbjct: 96 -----------------IQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDR 138
Query: 783 VDCGNPGRIENGKVTLPSNATF-YGATAFYQCDEN------WELEGVIRRMCQEN----G 831
+ CG P I NG + F YG+ Y+C+ +EL G C N G
Sbjct: 139 IPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVG 198
Query: 832 TWSLEPPICKEITCPDPSAQIKAGSGLLVV--TSTLSIGGEAHYQCERGYNLKGHQTRTC 889
WS P C P+ +G+LV S S+ ++C+ G+ +KG + C
Sbjct: 199 IWSGPAPQC---IIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKC 255
Query: 890 ISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLF-GSSVEYYCLSQYQRVGPFLRK 948
+ +W +P C + C+ P ++ + + + G V Y C Y G +
Sbjct: 256 QALNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMR 314
Query: 949 CLDDGRWSGEEPSCEL 964
C G WS P+CE+
Sbjct: 315 CTPQGDWSPAAPTCEV 330
Score = 96.3 bits (229), Expect = 5e-19
Identities = 74/237 (31%), Positives = 98/237 (41%), Gaps = 23/237 (9%)
Query: 743 YRIGALVKYRCEKGYKVIGESLST-CEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSN 801
+ IG + Y C GY G S C N W+G C+ C NP NG V +
Sbjct: 38 FPIGTYLNYECRPGYS--GRPFSIICLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKG 95
Query: 802 ATFYGATAFYQCDENWELEGVIRRMCQENG---TWSLEPPICKEITCPDPSAQIKAGSGL 858
F G+ Y C + + L G C +G W E PIC I C P I G +
Sbjct: 96 IQF-GSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPT-IANGDFI 153
Query: 859 LVVTSTLSIGGEAHYQCERG------YNLKGHQTRTCISK----GQWNGTVPVC-IPIDC 907
G Y+C G + L G + C S G W+G P C IP C
Sbjct: 154 STNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKC 213
Query: 908 RSPGNIENGKIVISNGSTLFGSS--VEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
+P N+ENG I++S+ +LF + VE+ C + GP KC +W E PSC
Sbjct: 214 -TPPNVENG-ILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSC 268
Score = 93.9 bits (223), Expect = 3e-18
Identities = 84/358 (23%), Positives = 141/358 (39%), Gaps = 38/358 (10%)
Query: 349 LPPTCGSPDKLLNTTILGND---YDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPS 405
+P C +P + N ++ ++ + + + ++C G ++ G + C+ W PS
Sbjct: 209 IPNKC-TPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPS 267
Query: 406 CKYVNCGGLTPIEDGDVALID-NRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAP 464
C V C + + D + + G YSC + L G C +G W AP
Sbjct: 268 CSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAP 326
Query: 465 RCLFDWCPD-PPAVSNASVTVNGH-KAGSLASYTCENGHILSGSTSVTCTLGGA---WSG 519
C C D + N V + + G+ + C+ G L GS++ C L G W+
Sbjct: 327 TCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNS 386
Query: 520 VPPSCKYVNCGTPTI-----HKGSFVLINGTTTYGSIAQFTCEP------DYWLNGAEEL 568
P C+ + C +P + H G + + +G +TC+P + L G +
Sbjct: 387 SVPVCEQIFCPSPPVIPNGRHTGKPLEV---FPFGKAVNYTCDPHPDRGTSFDLIGESTI 443
Query: 569 VCNRD----GKWSYDIPSCELTS-CPEPE----VPSGGYMEAFDYYVHSTINFHCEAGHK 619
C D G WS P C + C P+ A D+ + +++ + C +
Sbjct: 444 RCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEY- 502
Query: 620 LIGEP-NLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTT 676
G P ++ C + WS C+ C K P P M + +GS I YSCTT
Sbjct: 503 -YGRPFSITCLDNLVWSSPKDVCKRKSC-KTPPDPVNGMVHVITDIQVGSRINYSCTT 558
Score = 42.3 bits (95), Expect = 0.009
Identities = 19/57 (33%), Positives = 28/57 (49%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C P +A + +++N G Y C+ GY+L GA CT +GDW+ P C
Sbjct: 272 CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTC 328
Score = 37.5 bits (83), Expect = 0.26
Identities = 20/60 (33%), Positives = 27/60 (45%), Gaps = 5/60 (8%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGD---WTLEPPFC 58
C +P P N V + + I G+ Y C +GY L G+ C + GD W E P C
Sbjct: 79 CRNPPDPVNGMVHVI--KGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPIC 136
>AL691452-5|CAI16727.1| 559|Homo sapiens complement component
(3b/4b) receptor 1 (Knops blood group) protein.
Length = 559
Score = 185 bits (450), Expect = 9e-46
Identities = 143/547 (26%), Positives = 220/547 (40%), Gaps = 60/547 (10%)
Query: 368 DYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDN 427
++ +G+ + Y+C G+ S C K+ W+GA C+ +C +G V +I
Sbjct: 37 EFPIGTYLNYECRPGYSGR-PFSIICLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKG 95
Query: 428 RTTHGARALYSCRENFTLVGNPERTC---GDEGIWDGEAPRCLFDWCPDPPAVSNA---S 481
G++ YSC + + L+G+ TC GD IWD E P C C PP ++N S
Sbjct: 96 -IQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTIANGDFIS 154
Query: 482 VTVNGHKAGSLASYTCENG------HILSGSTSVTCTLG----GAWSGVPPSCKYVN-CG 530
GS+ +Y C G L G S+ CT G WSG P C N C
Sbjct: 155 TNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCT 214
Query: 531 TPTIHKGSFVLINGTT-TYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCP 589
P + G V N + + + +F C+P + + G + C KW ++PSC P
Sbjct: 215 PPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQP 274
Query: 590 EPEV--PSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCG 647
P+V + ++ + + CE G+ L G ++ C G+WS +PTCE C
Sbjct: 275 PPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCD 334
Query: 648 KLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCT---EEFQWSDSSPRCEEI 704
L LG+ + + C ++L G C E W+ S P CE+I
Sbjct: 335 DFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQI 394
Query: 705 RCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCE------KGYK 758
C P V N R G L + G V Y C+ +
Sbjct: 395 FCPSP--------PVIPNGRHTGKPL----------EVFPFGKTVNYTCDPHPDRGTSFD 436
Query: 759 VIGESLSTC----EDNGQWSGTTPTCQYV-DCGNPGRIENGKVTLPSNATFY--GATAFY 811
+IGES C + NG WS P C + C P K+ +NA+ + G + Y
Sbjct: 437 LIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKY 496
Query: 812 QCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEA 871
+C + C +N WS +CK +C P + +G++ V + + +G
Sbjct: 497 ECRPEY-YGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPV---NGMVHVITDIQVGSRI 552
Query: 872 HYQCERG 878
+Y C G
Sbjct: 553 NYSCTTG 559
Score = 173 bits (421), Expect = 3e-42
Identities = 144/535 (26%), Positives = 216/535 (40%), Gaps = 60/535 (11%)
Query: 437 YSCRENFTLVGNP-ERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASV-TVNGHKAGSLAS 494
Y CR ++ G P C +W G RC C +PP N V + G + GS
Sbjct: 46 YECRPGYS--GRPFSIICLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKGIQFGSQIK 103
Query: 495 YTCENGHILSGSTSVTCTLGG---AWSGVPPSCKYVNCGTP-TIHKGSFVLINGTTT-YG 549
Y+C G+ L GS+S TC + G W P C + CG P TI G F+ N YG
Sbjct: 104 YSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTIANGDFISTNRENFHYG 163
Query: 550 SIAQFTCEPD------YWLNGAEELVC--NRD--GKWSYDIPSCELTS-CPEPEVPSGGY 598
S+ + C P + L G + C N D G WS P C + + C P V +G
Sbjct: 164 SVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGIL 223
Query: 599 MEAFD--YYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGT 656
+ + ++ + F C+ G + G + CQ +W + P+C + C P + +
Sbjct: 224 VSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRV-CQPPPDVLHAE 282
Query: 657 MELLNGTTHL-GSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKS 715
+ G + YSC Y L G CT + WS ++P CE C D +
Sbjct: 283 RTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDFM----- 337
Query: 716 IVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQ--- 772
+G L + ++GA V + C++G+++ G S S C G
Sbjct: 338 ------GQLLNGRVLFPVN--------LQLGAKVDFVCDEGFQLKGSSASYCVLAGMESL 383
Query: 773 WSGTTPTCQYVDCGNPGRIENGKVT-LPSNATFYGATAFYQCDEN------WELEGVIRR 825
W+ + P C+ + C +P I NG+ T P +G T Y CD + ++L G
Sbjct: 384 WNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTI 443
Query: 826 MC----QENGTWSLEPPICKEIT-CPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYN 880
C Q NG WS P C + C P + A S IG Y+C Y
Sbjct: 444 RCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYY 503
Query: 881 LKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYC 935
+ TC+ W+ VC C++P + NG + + + GS + Y C
Sbjct: 504 GRPFSI-TCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQV-GSRINYSC 556
Score = 169 bits (411), Expect = 5e-41
Identities = 135/509 (26%), Positives = 209/509 (41%), Gaps = 59/509 (11%)
Query: 490 GSLASYTCENGHILSGST-SVTCTLGGAWSGVPPSCKYVNCGTPTIHKGSFVLINGTTTY 548
G+ +Y C G+ SG S+ C W+G C+ +C P V + +
Sbjct: 41 GTYLNYECRPGY--SGRPFSIICLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKGIQF 98
Query: 549 GSIAQFTCEPDYWLNGAEELVCNRDGK---WSYDIPSCELTSCP-EPEVPSGGYMEAF-- 602
GS +++C Y L G+ C G W + P C+ C P + +G ++
Sbjct: 99 GSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTIANGDFISTNRE 158
Query: 603 DYYVHSTINFHCEAGH------KLIGEPNLVC----QQDGEWSGDSPTCEYIDCGKLPTL 652
+++ S + + C G +L+GEP++ C Q G WSG +P C + P +
Sbjct: 159 NFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNV 218
Query: 653 PYGTMELLNGTTH-LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIV 711
G + N + L V+++ C + + GP R C +W P C + C P
Sbjct: 219 ENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRV-CQPP-- 275
Query: 712 AEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNG 771
D H R DN + G V Y CE GY + G + C G
Sbjct: 276 ----------PDVLHAERTQRDKDN------FSPGQEVFYSCEPGYDLRGAASMRCTPQG 319
Query: 772 QWSGTTPTCQYVDCGN-PGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQEN 830
WS PTC+ C + G++ NG+V P N GA + CDE ++L+G C
Sbjct: 320 DWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQL-GAKVDFVCDEGFQLKGSSASYCVLA 378
Query: 831 GT---WSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCE----RG--YNL 881
G W+ P+C++I CP P I G G +Y C+ RG ++L
Sbjct: 379 GMESLWNSSVPVCEQIFCPSPPV-IPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDL 437
Query: 882 KGHQTRTCIS----KGQWNGTVPVC-IPIDCRSPGNIENGKIVISNGSTLF--GSSVEYY 934
G T C S G W+ P C I C++P + K+ ++ F G+S++Y
Sbjct: 438 IGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYE 497
Query: 935 CLSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
C +Y PF CLD+ WS + C+
Sbjct: 498 CRPEYYG-RPFSITCLDNLVWSSPKDVCK 525
Score = 162 bits (393), Expect = 7e-39
Identities = 136/500 (27%), Positives = 201/500 (40%), Gaps = 59/500 (11%)
Query: 352 TCGSPDKLLNTTI-LGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDG---FWSGAPPSCK 407
+C +P +N + + GS+I Y C +G+ L+G S C G W P C
Sbjct: 78 SCRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICD 137
Query: 408 YVNCGGLTPIEDGDVALIDNRTTH-GARALYSC------RENFTLVGNPERTC--GDE-- 456
+ CG I +GD + H G+ Y C R+ F LVG P C D+
Sbjct: 138 RIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQV 197
Query: 457 GIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGSL---ASYTCENGHILSGSTSVTCTL 513
GIW G AP+C+ PP V N + + SL + C+ G ++ G V C
Sbjct: 198 GIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQA 257
Query: 514 GGAWSGVPPSCKYVNCGTP--TIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCN 571
W PSC V C P +H + G ++CEP Y L GA + C
Sbjct: 258 LNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCT 316
Query: 572 RDGKWSYDIPSCELTSCPE--PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQ 629
G WS P+CE+ SC + ++ +G + + + + ++F C+ G +L G C
Sbjct: 317 PQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCV 376
Query: 630 QDGE---WSGDSPTCEYIDCGKLPTLPYG--TMELLNGTTHLGSVIQYSCT------TNY 678
G W+ P CE I C P +P G T + L G + Y+C T++
Sbjct: 377 LAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLE-VFPFGKTVNYTCDPHPDRGTSF 435
Query: 679 RLVGPVRRTCTEEFQ----WSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTS 734
L+G CT + Q WS +PRC + G+ ++ H L
Sbjct: 436 DLIGESTIRCTSDPQGNGVWSSPAPRC----------------GILGHCQAPDHFLFAKL 479
Query: 735 DNRDVGNTYRIGALVKYRCEKGYKVIGESLS-TCEDNGQWSGTTPTCQYVDCGNPGRIEN 793
+ + + IG +KY C Y G S TC DN WS C+ C P N
Sbjct: 480 KTQTNASDFPIGTSLKYECRPEY--YGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVN 537
Query: 794 GKVTLPSNATFYGATAFYQC 813
G V + ++ G+ Y C
Sbjct: 538 GMVHVITDIQ-VGSRINYSC 556
Score = 101 bits (243), Expect = 1e-20
Identities = 80/316 (25%), Positives = 124/316 (39%), Gaps = 42/316 (13%)
Query: 666 LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRS 725
+G+ + Y C Y P C + W+ + RC C +P +V V
Sbjct: 40 IGTYLNYECRPGYS-GRPFSIICLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKG--- 95
Query: 726 HGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTCQY 782
+ G+ +KY C KGY++IG S +TC +G W TP C
Sbjct: 96 -----------------IQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDR 138
Query: 783 VDCGNPGRIENGKVTLPSNATF-YGATAFYQCDEN------WELEGVIRRMCQEN----G 831
+ CG P I NG + F YG+ Y+C+ +EL G C N G
Sbjct: 139 IPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVG 198
Query: 832 TWSLEPPICKEITCPDPSAQIKAGSGLLVV--TSTLSIGGEAHYQCERGYNLKGHQTRTC 889
WS P C P+ +G+LV S S+ ++C+ G+ +KG + C
Sbjct: 199 IWSGPAPQC---IIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKC 255
Query: 890 ISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLF-GSSVEYYCLSQYQRVGPFLRK 948
+ +W +P C + C+ P ++ + + + G V Y C Y G +
Sbjct: 256 QALNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMR 314
Query: 949 CLDDGRWSGEEPSCEL 964
C G WS P+CE+
Sbjct: 315 CTPQGDWSPAAPTCEV 330
Score = 96.3 bits (229), Expect = 5e-19
Identities = 74/237 (31%), Positives = 98/237 (41%), Gaps = 23/237 (9%)
Query: 743 YRIGALVKYRCEKGYKVIGESLST-CEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSN 801
+ IG + Y C GY G S C N W+G C+ C NP NG V +
Sbjct: 38 FPIGTYLNYECRPGYS--GRPFSIICLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKG 95
Query: 802 ATFYGATAFYQCDENWELEGVIRRMCQENG---TWSLEPPICKEITCPDPSAQIKAGSGL 858
F G+ Y C + + L G C +G W E PIC I C P I G +
Sbjct: 96 IQF-GSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPT-IANGDFI 153
Query: 859 LVVTSTLSIGGEAHYQCERG------YNLKGHQTRTCISK----GQWNGTVPVC-IPIDC 907
G Y+C G + L G + C S G W+G P C IP C
Sbjct: 154 STNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKC 213
Query: 908 RSPGNIENGKIVISNGSTLFGSS--VEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
+P N+ENG I++S+ +LF + VE+ C + GP KC +W E PSC
Sbjct: 214 -TPPNVENG-ILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSC 268
Score = 42.3 bits (95), Expect = 0.009
Identities = 19/57 (33%), Positives = 28/57 (49%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C P +A + +++N G Y C+ GY+L GA CT +GDW+ P C
Sbjct: 272 CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTC 328
Score = 37.5 bits (83), Expect = 0.26
Identities = 20/60 (33%), Positives = 27/60 (45%), Gaps = 5/60 (8%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGD---WTLEPPFC 58
C +P P N V + + I G+ Y C +GY L G+ C + GD W E P C
Sbjct: 79 CRNPPDPVNGMVHVI--KGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPIC 136
>AL691452-4|CAI16726.1| 559|Homo sapiens complement component
(3b/4b) receptor 1 (Knops blood group) protein.
Length = 559
Score = 185 bits (450), Expect = 9e-46
Identities = 143/547 (26%), Positives = 220/547 (40%), Gaps = 60/547 (10%)
Query: 368 DYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDN 427
++ +G+ + Y+C G+ S C K+ W+GA C+ +C +G V +I
Sbjct: 37 EFPIGTYLNYECRPGYSGR-PFSIICLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKG 95
Query: 428 RTTHGARALYSCRENFTLVGNPERTC---GDEGIWDGEAPRCLFDWCPDPPAVSNA---S 481
G++ YSC + + L+G+ TC GD IWD E P C C PP ++N S
Sbjct: 96 -IQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTITNGDFIS 154
Query: 482 VTVNGHKAGSLASYTCENG------HILSGSTSVTCTLG----GAWSGVPPSCKYVN-CG 530
GS+ +Y C G L G S+ CT G WSG P C N C
Sbjct: 155 TNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCT 214
Query: 531 TPTIHKGSFVLINGTT-TYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCP 589
P + G V N + + + +F C+P + + G + C KW ++PSC P
Sbjct: 215 PPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQP 274
Query: 590 EPEV--PSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCG 647
P+V + ++ + + CE G+ L G ++ C G+WS +PTCE C
Sbjct: 275 PPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCD 334
Query: 648 KLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCT---EEFQWSDSSPRCEEI 704
L LG+ + + C ++L G C E W+ S P CE+I
Sbjct: 335 DFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQI 394
Query: 705 RCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCE------KGYK 758
C P V N R G L + G V Y C+ +
Sbjct: 395 FCPSP--------PVIPNGRHTGKPL----------EVFPFGKTVNYTCDPHPDRGTSFD 436
Query: 759 VIGESLSTC----EDNGQWSGTTPTCQYV-DCGNPGRIENGKVTLPSNATFY--GATAFY 811
+IGES C + NG WS P C + C P K+ +NA+ + G + Y
Sbjct: 437 LIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKY 496
Query: 812 QCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEA 871
+C + C +N WS +CK +C P + +G++ V + + +G
Sbjct: 497 ECRPEY-YGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPV---NGMVHVITDIQVGSRI 552
Query: 872 HYQCERG 878
+Y C G
Sbjct: 553 NYSCTTG 559
Score = 173 bits (421), Expect = 3e-42
Identities = 144/535 (26%), Positives = 216/535 (40%), Gaps = 60/535 (11%)
Query: 437 YSCRENFTLVGNP-ERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASV-TVNGHKAGSLAS 494
Y CR ++ G P C +W G RC C +PP N V + G + GS
Sbjct: 46 YECRPGYS--GRPFSIICLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKGIQFGSQIK 103
Query: 495 YTCENGHILSGSTSVTCTLGG---AWSGVPPSCKYVNCGTP-TIHKGSFVLINGTTT-YG 549
Y+C G+ L GS+S TC + G W P C + CG P TI G F+ N YG
Sbjct: 104 YSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTITNGDFISTNRENFHYG 163
Query: 550 SIAQFTCEPD------YWLNGAEELVC--NRD--GKWSYDIPSCELTS-CPEPEVPSGGY 598
S+ + C P + L G + C N D G WS P C + + C P V +G
Sbjct: 164 SVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGIL 223
Query: 599 MEAFD--YYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGT 656
+ + ++ + F C+ G + G + CQ +W + P+C + C P + +
Sbjct: 224 VSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRV-CQPPPDVLHAE 282
Query: 657 MELLNGTTHL-GSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKS 715
+ G + YSC Y L G CT + WS ++P CE C D +
Sbjct: 283 RTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDFM----- 337
Query: 716 IVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQ--- 772
+G L + ++GA V + C++G+++ G S S C G
Sbjct: 338 ------GQLLNGRVLFPVN--------LQLGAKVDFVCDEGFQLKGSSASYCVLAGMESL 383
Query: 773 WSGTTPTCQYVDCGNPGRIENGKVT-LPSNATFYGATAFYQCDEN------WELEGVIRR 825
W+ + P C+ + C +P I NG+ T P +G T Y CD + ++L G
Sbjct: 384 WNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTI 443
Query: 826 MC----QENGTWSLEPPICKEIT-CPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYN 880
C Q NG WS P C + C P + A S IG Y+C Y
Sbjct: 444 RCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYY 503
Query: 881 LKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYC 935
+ TC+ W+ VC C++P + NG + + + GS + Y C
Sbjct: 504 GRPFSI-TCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQV-GSRINYSC 556
Score = 169 bits (411), Expect = 5e-41
Identities = 135/509 (26%), Positives = 209/509 (41%), Gaps = 59/509 (11%)
Query: 490 GSLASYTCENGHILSGST-SVTCTLGGAWSGVPPSCKYVNCGTPTIHKGSFVLINGTTTY 548
G+ +Y C G+ SG S+ C W+G C+ +C P V + +
Sbjct: 41 GTYLNYECRPGY--SGRPFSIICLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKGIQF 98
Query: 549 GSIAQFTCEPDYWLNGAEELVCNRDGK---WSYDIPSCELTSCP-EPEVPSGGYMEAF-- 602
GS +++C Y L G+ C G W + P C+ C P + +G ++
Sbjct: 99 GSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTITNGDFISTNRE 158
Query: 603 DYYVHSTINFHCEAGH------KLIGEPNLVC----QQDGEWSGDSPTCEYIDCGKLPTL 652
+++ S + + C G +L+GEP++ C Q G WSG +P C + P +
Sbjct: 159 NFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNV 218
Query: 653 PYGTMELLNGTTH-LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIV 711
G + N + L V+++ C + + GP R C +W P C + C P
Sbjct: 219 ENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRV-CQPP-- 275
Query: 712 AEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNG 771
D H R DN + G V Y CE GY + G + C G
Sbjct: 276 ----------PDVLHAERTQRDKDN------FSPGQEVFYSCEPGYDLRGAASMRCTPQG 319
Query: 772 QWSGTTPTCQYVDCGN-PGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQEN 830
WS PTC+ C + G++ NG+V P N GA + CDE ++L+G C
Sbjct: 320 DWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQL-GAKVDFVCDEGFQLKGSSASYCVLA 378
Query: 831 GT---WSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCE----RG--YNL 881
G W+ P+C++I CP P I G G +Y C+ RG ++L
Sbjct: 379 GMESLWNSSVPVCEQIFCPSPPV-IPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDL 437
Query: 882 KGHQTRTCIS----KGQWNGTVPVC-IPIDCRSPGNIENGKIVISNGSTLF--GSSVEYY 934
G T C S G W+ P C I C++P + K+ ++ F G+S++Y
Sbjct: 438 IGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYE 497
Query: 935 CLSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
C +Y PF CLD+ WS + C+
Sbjct: 498 CRPEYYG-RPFSITCLDNLVWSSPKDVCK 525
Score = 162 bits (393), Expect = 7e-39
Identities = 136/500 (27%), Positives = 201/500 (40%), Gaps = 59/500 (11%)
Query: 352 TCGSPDKLLNTTI-LGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDG---FWSGAPPSCK 407
+C +P +N + + GS+I Y C +G+ L+G S C G W P C
Sbjct: 78 SCRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICD 137
Query: 408 YVNCGGLTPIEDGDVALIDNRTTH-GARALYSC------RENFTLVGNPERTC--GDE-- 456
+ CG I +GD + H G+ Y C R+ F LVG P C D+
Sbjct: 138 RIPCGLPPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQV 197
Query: 457 GIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGSL---ASYTCENGHILSGSTSVTCTL 513
GIW G AP+C+ PP V N + + SL + C+ G ++ G V C
Sbjct: 198 GIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQA 257
Query: 514 GGAWSGVPPSCKYVNCGTP--TIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCN 571
W PSC V C P +H + G ++CEP Y L GA + C
Sbjct: 258 LNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCT 316
Query: 572 RDGKWSYDIPSCELTSCPE--PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQ 629
G WS P+CE+ SC + ++ +G + + + + ++F C+ G +L G C
Sbjct: 317 PQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCV 376
Query: 630 QDGE---WSGDSPTCEYIDCGKLPTLPYG--TMELLNGTTHLGSVIQYSCT------TNY 678
G W+ P CE I C P +P G T + L G + Y+C T++
Sbjct: 377 LAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLE-VFPFGKTVNYTCDPHPDRGTSF 435
Query: 679 RLVGPVRRTCTEEFQ----WSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTS 734
L+G CT + Q WS +PRC + G+ ++ H L
Sbjct: 436 DLIGESTIRCTSDPQGNGVWSSPAPRC----------------GILGHCQAPDHFLFAKL 479
Query: 735 DNRDVGNTYRIGALVKYRCEKGYKVIGESLS-TCEDNGQWSGTTPTCQYVDCGNPGRIEN 793
+ + + IG +KY C Y G S TC DN WS C+ C P N
Sbjct: 480 KTQTNASDFPIGTSLKYECRPEY--YGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVN 537
Query: 794 GKVTLPSNATFYGATAFYQC 813
G V + ++ G+ Y C
Sbjct: 538 GMVHVITDIQ-VGSRINYSC 556
Score = 101 bits (243), Expect = 1e-20
Identities = 80/316 (25%), Positives = 124/316 (39%), Gaps = 42/316 (13%)
Query: 666 LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRS 725
+G+ + Y C Y P C + W+ + RC C +P +V V
Sbjct: 40 IGTYLNYECRPGYS-GRPFSIICLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKG--- 95
Query: 726 HGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTCQY 782
+ G+ +KY C KGY++IG S +TC +G W TP C
Sbjct: 96 -----------------IQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDR 138
Query: 783 VDCGNPGRIENGKVTLPSNATF-YGATAFYQCDEN------WELEGVIRRMCQEN----G 831
+ CG P I NG + F YG+ Y+C+ +EL G C N G
Sbjct: 139 IPCGLPPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVG 198
Query: 832 TWSLEPPICKEITCPDPSAQIKAGSGLLVV--TSTLSIGGEAHYQCERGYNLKGHQTRTC 889
WS P C P+ +G+LV S S+ ++C+ G+ +KG + C
Sbjct: 199 IWSGPAPQC---IIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKC 255
Query: 890 ISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLF-GSSVEYYCLSQYQRVGPFLRK 948
+ +W +P C + C+ P ++ + + + G V Y C Y G +
Sbjct: 256 QALNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMR 314
Query: 949 CLDDGRWSGEEPSCEL 964
C G WS P+CE+
Sbjct: 315 CTPQGDWSPAAPTCEV 330
Score = 96.3 bits (229), Expect = 5e-19
Identities = 74/237 (31%), Positives = 98/237 (41%), Gaps = 23/237 (9%)
Query: 743 YRIGALVKYRCEKGYKVIGESLST-CEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSN 801
+ IG + Y C GY G S C N W+G C+ C NP NG V +
Sbjct: 38 FPIGTYLNYECRPGYS--GRPFSIICLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKG 95
Query: 802 ATFYGATAFYQCDENWELEGVIRRMCQENG---TWSLEPPICKEITCPDPSAQIKAGSGL 858
F G+ Y C + + L G C +G W E PIC I C P I G +
Sbjct: 96 IQF-GSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPT-ITNGDFI 153
Query: 859 LVVTSTLSIGGEAHYQCERG------YNLKGHQTRTCISK----GQWNGTVPVC-IPIDC 907
G Y+C G + L G + C S G W+G P C IP C
Sbjct: 154 STNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKC 213
Query: 908 RSPGNIENGKIVISNGSTLFGSS--VEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
+P N+ENG I++S+ +LF + VE+ C + GP KC +W E PSC
Sbjct: 214 -TPPNVENG-ILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSC 268
Score = 42.3 bits (95), Expect = 0.009
Identities = 19/57 (33%), Positives = 28/57 (49%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C P +A + +++N G Y C+ GY+L GA CT +GDW+ P C
Sbjct: 272 CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTC 328
Score = 37.5 bits (83), Expect = 0.26
Identities = 20/60 (33%), Positives = 27/60 (45%), Gaps = 5/60 (8%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGD---WTLEPPFC 58
C +P P N V + + I G+ Y C +GY L G+ C + GD W E P C
Sbjct: 79 CRNPPDPVNGMVHVI--KGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPIC 136
>M61893-1|AAA52375.1| 610|Homo sapiens endothelial leukocyte
adhesion molecule 1 protein.
Length = 610
Score = 177 bits (432), Expect = 1e-43
Identities = 107/417 (25%), Positives = 181/417 (43%), Gaps = 33/417 (7%)
Query: 499 NGHILSGSTSVTCTLGGAWSGVPPSCKYVNC-GTPTIHKGSFVLIN--GTTTYGSIAQFT 555
+G + + TC +SG+ + VNC + GS V + G +Y S +
Sbjct: 151 HGECVETINNYTCKCDPGFSGLKCE-QIVNCTALESPEHGSLVCSHPLGNFSYNSSCSIS 209
Query: 556 CEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFD----YYVHSTIN 611
C+ Y + E + C G+WS IP+C + C P+ G++E F + ++T
Sbjct: 210 CDRGYLPSSMETMQCMSSGEWSAPIPACNVVECDAVTNPANGFVECFQNPGSFPWNTTCT 269
Query: 612 FHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLN---GTTHLGS 668
F CE G +L+G +L C G W + PTC+ + C + G++ + G S
Sbjct: 270 FDCEEGFELMGAQSLQCTSSGNWDNEKPTCKAVTCRAVRQPQNGSVRCSHSPAGEFTFKS 329
Query: 669 VIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGH 728
++C + L GP + CT + QW+ P CE +C+ +++ +R + +
Sbjct: 330 SCNFTCEEGFMLQGPAQVECTTQGQWTQQIPVCEAFQCT----------ALSNPERGYMN 379
Query: 729 TLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNP 788
L S ++R G+ ++ CE+G+ + G C G+W PTC+ V C
Sbjct: 380 CLPSAS------GSFRYGSSCEFSCEQGFVLKGSKRLQCGPTGEWDNEKPTCEAVRCDAV 433
Query: 789 GRIENGKVTL---PSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITC 845
+ G V P Y ++ + C+E +EL G + C G W+ E P C+ + C
Sbjct: 434 HQPPKGLVRCAHSPIGEFTYKSSCAFSCEEGFELHGSTQLECTSQGQWTEEVPSCQVVKC 493
Query: 846 PDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVC 902
S+ G + + G + C G+ L G RTC + G W+G +P C
Sbjct: 494 ---SSLAVPGKINMSCSGEPVFGTVCKFACPEGWTLNGSAARTCGATGHWSGLLPTC 547
Score = 173 bits (422), Expect = 2e-42
Identities = 105/373 (28%), Positives = 158/373 (42%), Gaps = 19/373 (5%)
Query: 365 LGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVAL 424
LGN + S C G++ ++ C G WS P+C V C +T +G V
Sbjct: 197 LGN-FSYNSSCSISCDRGYLPSSMETMQCMSSGEWSAPIPACNVVECDAVTNPANGFVEC 255
Query: 425 IDNRTTH--GARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASV 482
N + + C E F L+G C G WD E P C C N SV
Sbjct: 256 FQNPGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGNWDNEKPTCKAVTCRAVRQPQNGSV 315
Query: 483 TVNGHKAG-----SLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTIHKG 537
+ AG S ++TCE G +L G V CT G W+ P C+ C + +
Sbjct: 316 RCSHSPAGEFTFKSSCNFTCEEGFMLQGPAQVECTTQGQWTQQIPVCEAFQCTALSNPER 375
Query: 538 SFV----LINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEV 593
++ +G+ YGS +F+CE + L G++ L C G+W + P+CE C
Sbjct: 376 GYMNCLPSASGSFRYGSSCEFSCEQGFVLKGSKRLQCGPTGEWDNEKPTCEAVRCDAVHQ 435
Query: 594 PSGGYMEAF-----DYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGK 648
P G + ++ S+ F CE G +L G L C G+W+ + P+C+ + C
Sbjct: 436 PPKGLVRCAHSPIGEFTYKSSCAFSCEEGFELHGSTQLECTSQGQWTEEVPSCQVVKCSS 495
Query: 649 LPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSD 708
L +P +G G+V +++C + L G RTC WS P CE S+
Sbjct: 496 L-AVPGKINMSCSGEPVFGTVCKFACPEGWTLNGSAARTCGATGHWSGLLPTCEAPTESN 554
Query: 709 -PIVAEKSIVSVT 720
P+VA S ++
Sbjct: 555 IPLVAGLSAAGLS 567
Score = 165 bits (402), Expect = 6e-40
Identities = 143/570 (25%), Positives = 211/570 (37%), Gaps = 77/570 (13%)
Query: 236 SFDEARKQCQSHGGDLIHGFQGATSSFLTQELERRKAQLKTQLVWIGAQKEPGLTSRTWQ 295
++DEA CQ L+ +L L WIG +K + W
Sbjct: 32 TYDEASAYCQQRYTHLVAIQNKEEIEYLNSILS-----YSPSYYWIGIRK----VNNVWV 82
Query: 296 WVDGE---LVSKPSWGKDQPNNYNGEQNCVVLDGGRG---WLWNDVGCNLDYLHWICQYL 349
WV + +W +PNN +++CV + R +WND C+ L +C
Sbjct: 83 WVGTQKPLTEEAKNWAPGEPNNRQKDEDCVEIYIKREKDVGMWNDERCSKKKLA-LCYTA 141
Query: 350 PPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYV 409
T NT+ G+ +C E + CK D +SG + V
Sbjct: 142 ACT--------NTSCSGHG---------ECVETI-----NNYTCKCDPGFSGLKCE-QIV 178
Query: 410 NCGGLTPIEDGDVALID--NRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL 467
NC L E G + ++ + SC + C G W P C
Sbjct: 179 NCTALESPEHGSLVCSHPLGNFSYNSSCSISCDRGYLPSSMETMQCMSSGEWSAPIPACN 238
Query: 468 FDWCPDPPAVSNASVTVNGHKAG----SLASYTCENGHILSGSTSVTCTLGGAWSGVPPS 523
C +N V + + ++ CE G L G+ S+ CT G W P+
Sbjct: 239 VVECDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGNWDNEKPT 298
Query: 524 CKYVNCGTPTIHKGSFVLIN----GTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYD 579
CK V C + V + G T+ S FTCE + L G ++ C G+W+
Sbjct: 299 CKAVTCRAVRQPQNGSVRCSHSPAGEFTFKSSCNFTCEEGFMLQGPAQVECTTQGQWTQQ 358
Query: 580 IPSCELTSCPEPEVPSGGYMEAF-----DYYVHSTINFHCEAGHKLIGEPNLVCQQDGEW 634
IP CE C P GYM + S+ F CE G L G L C GEW
Sbjct: 359 IPVCEAFQCTALSNPERGYMNCLPSASGSFRYGSSCEFSCEQGFVLKGSKRLQCGPTGEW 418
Query: 635 SGDSPTCEYIDCGKLPTLPYGTMELLN---GTTHLGSVIQYSCTTNYRLVGPVRRTCTEE 691
+ PTCE + C + P G + + G S +SC + L G + CT +
Sbjct: 419 DNEKPTCEAVRCDAVHQPPKGLVRCAHSPIGEFTYKSSCAFSCEEGFELHGSTQLECTSQ 478
Query: 692 FQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKY 751
QW++ P C+ ++CS V K +S +G G + K+
Sbjct: 479 GQWTEEVPSCQVVKCSSLAVPGKINMSCSGEP--------------------VFGTVCKF 518
Query: 752 RCEKGYKVIGESLSTCEDNGQWSGTTPTCQ 781
C +G+ + G + TC G WSG PTC+
Sbjct: 519 ACPEGWTLNGSAARTCGATGHWSGLLPTCE 548
Score = 148 bits (358), Expect = 1e-34
Identities = 106/404 (26%), Positives = 166/404 (41%), Gaps = 38/404 (9%)
Query: 583 CE-LTSCPEPEVPSGGYMEAF----DYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGD 637
CE + +C E P G + ++ +S+ + C+ G+ + C GEWS
Sbjct: 174 CEQIVNCTALESPEHGSLVCSHPLGNFSYNSSCSISCDRGYLPSSMETMQCMSSGEWSAP 233
Query: 638 SPTCEYIDCGKLPTLPYGTMELLN--GTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWS 695
P C ++C + G +E G+ + + C + L+G CT W
Sbjct: 234 IPACNVVECDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGNWD 293
Query: 696 DSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEK 755
+ P C+ + C V + SV + G ++S N + CE+
Sbjct: 294 NEKPTCKAVTCR--AVRQPQNGSVRCSHSPAGEFTFKSSCN--------------FTCEE 337
Query: 756 GYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVT-LPS-NATF-YGATAFYQ 812
G+ + G + C GQW+ P C+ C E G + LPS + +F YG++ +
Sbjct: 338 GFMLQGPAQVECTTQGQWTQQIPVCEAFQCTALSNPERGYMNCLPSASGSFRYGSSCEFS 397
Query: 813 CDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIG---- 868
C++ + L+G R C G W E P C+ + C D Q G LV + IG
Sbjct: 398 CEQGFVLKGSKRLQCGPTGEWDNEKPTCEAVRC-DAVHQPPKG---LVRCAHSPIGEFTY 453
Query: 869 -GEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVIS-NGSTL 926
+ CE G+ L G C S+GQW VP C + C S GKI +S +G +
Sbjct: 454 KSSCAFSCEEGFELHGSTQLECTSQGQWTEEVPSCQVVKCSSLA--VPGKINMSCSGEPV 511
Query: 927 FGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCELATNEAV 970
FG+ ++ C + G R C G WSG P+CE T +
Sbjct: 512 FGTVCKFACPEGWTLNGSAARTCGATGHWSGLLPTCEAPTESNI 555
Score = 81.8 bits (193), Expect = 1e-14
Identities = 50/203 (24%), Positives = 79/203 (38%), Gaps = 6/203 (2%)
Query: 766 TCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTL--PSNATFYGATAFYQCDENWELEGVI 823
TC+ + +SG Q V+C E+G + P Y ++ CD + +
Sbjct: 162 TCKCDPGFSGLKCE-QIVNCTALESPEHGSLVCSHPLGNFSYNSSCSISCDRGYLPSSME 220
Query: 824 RRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKG 883
C +G WS P C + C + + + CE G+ L G
Sbjct: 221 TMQCMSSGEWSAPIPACNVVECDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMG 280
Query: 884 HQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISN---GSTLFGSSVEYYCLSQYQ 940
Q+ C S G W+ P C + CR+ +NG + S+ G F SS + C +
Sbjct: 281 AQSLQCTSSGNWDNEKPTCKAVTCRAVRQPQNGSVRCSHSPAGEFTFKSSCNFTCEEGFM 340
Query: 941 RVGPFLRKCLDDGRWSGEEPSCE 963
GP +C G+W+ + P CE
Sbjct: 341 LQGPAQVECTTQGQWTQQIPVCE 363
Score = 46.4 bits (105), Expect = 6e-04
Identities = 26/73 (35%), Positives = 35/73 (47%), Gaps = 3/73 (4%)
Query: 2 CGHPAVPPNARVS-IPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCG- 59
C P N V N + T ++C+EG+EL GA+ +CT G+W E P C
Sbjct: 242 CDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGNWDNEKPTCKA 301
Query: 60 -TNVAFRKPANQS 71
T A R+P N S
Sbjct: 302 VTCRAVRQPQNGS 314
Score = 44.0 bits (99), Expect = 0.003
Identities = 16/30 (53%), Positives = 21/30 (70%)
Query: 29 YECDEGYELFGARQRECTLRGDWTLEPPFC 58
+ C+EG+EL G+ Q ECT +G WT E P C
Sbjct: 459 FSCEEGFELHGSTQLECTSQGQWTEEVPSC 488
Score = 38.3 bits (85), Expect = 0.15
Identities = 14/30 (46%), Positives = 19/30 (63%)
Query: 29 YECDEGYELFGARQRECTLRGDWTLEPPFC 58
+ C+EG+ L G Q ECT +G WT + P C
Sbjct: 333 FTCEEGFMLQGPAQVECTTQGQWTQQIPVC 362
Score = 38.3 bits (85), Expect = 0.15
Identities = 20/58 (34%), Positives = 27/58 (46%), Gaps = 2/58 (3%)
Query: 1 RCGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
+C AVP +S E V GT+ + C EG+ L G+ R C G W+ P C
Sbjct: 492 KCSSLAVPGKINMSCSGEP--VFGTVCKFACPEGWTLNGSAARTCGATGHWSGLLPTC 547
Score = 33.5 bits (73), Expect = 4.2
Identities = 11/35 (31%), Positives = 21/35 (60%)
Query: 24 GTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
G+ + C++G+ L G+++ +C G+W E P C
Sbjct: 391 GSSCEFSCEQGFVLKGSKRLQCGPTGEWDNEKPTC 425
>M30640-1|AAA52377.1| 610|Homo sapiens endothelial leukocyte
adhesion molecule 1 protein.
Length = 610
Score = 177 bits (432), Expect = 1e-43
Identities = 107/417 (25%), Positives = 181/417 (43%), Gaps = 33/417 (7%)
Query: 499 NGHILSGSTSVTCTLGGAWSGVPPSCKYVNC-GTPTIHKGSFVLIN--GTTTYGSIAQFT 555
+G + + TC +SG+ + VNC + GS V + G +Y S +
Sbjct: 151 HGECVETINNYTCKCDPGFSGLKCE-QIVNCTALESPEHGSLVCSHPLGNFSYNSSCSIS 209
Query: 556 CEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFD----YYVHSTIN 611
C+ Y + E + C G+WS IP+C + C P+ G++E F + ++T
Sbjct: 210 CDRGYLPSSMETMQCMSSGEWSAPIPACNVVECDAVTNPANGFVECFQNPGSFPWNTTCT 269
Query: 612 FHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLN---GTTHLGS 668
F CE G +L+G +L C G W + PTC+ + C + G++ + G S
Sbjct: 270 FDCEEGFELMGAQSLQCTSSGNWDNEKPTCKAVTCRAVRQPQNGSVRCSHSPAGEFTFKS 329
Query: 669 VIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGH 728
++C + L GP + CT + QW+ P CE +C+ +++ +R + +
Sbjct: 330 SCNFTCEEGFMLQGPAQVECTTQGQWTQQIPVCEAFQCT----------ALSNPERGYMN 379
Query: 729 TLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNP 788
L S ++R G+ ++ CE+G+ + G C G+W PTC+ V C
Sbjct: 380 CLPSAS------GSFRYGSSCEFSCEQGFVLKGSKRLQCGPTGEWDNEKPTCEAVRCDAV 433
Query: 789 GRIENGKVTL---PSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITC 845
+ G V P Y ++ + C+E +EL G + C G W+ E P C+ + C
Sbjct: 434 HQPPKGLVRCAHSPIGEFTYKSSCAFSCEEGFELHGSTQLECTSQGQWTEEVPSCQVVKC 493
Query: 846 PDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVC 902
S+ G + + G + C G+ L G RTC + G W+G +P C
Sbjct: 494 ---SSLAVPGKINMSCSGEPVFGTVCKFACPEGWTLNGSAARTCGATGHWSGLLPTC 547
Score = 173 bits (422), Expect = 2e-42
Identities = 105/373 (28%), Positives = 158/373 (42%), Gaps = 19/373 (5%)
Query: 365 LGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVAL 424
LGN + S C G++ ++ C G WS P+C V C +T +G V
Sbjct: 197 LGN-FSYNSSCSISCDRGYLPSSMETMQCMSSGEWSAPIPACNVVECDAVTNPANGFVEC 255
Query: 425 IDNRTTH--GARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASV 482
N + + C E F L+G C G WD E P C C N SV
Sbjct: 256 FQNPGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGNWDNEKPTCKAVTCRAVRQPQNGSV 315
Query: 483 TVNGHKAG-----SLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTIHKG 537
+ AG S ++TCE G +L G V CT G W+ P C+ C + +
Sbjct: 316 RCSHSPAGEFTFKSSCNFTCEEGFMLQGPAQVECTTQGQWTQQIPVCEAFQCTALSNPER 375
Query: 538 SFV----LINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEV 593
++ +G+ YGS +F+CE + L G++ L C G+W + P+CE C
Sbjct: 376 GYMNCLPSASGSFRYGSSCEFSCEQGFVLKGSKRLQCGPTGEWDNEKPTCEAVRCDAVHQ 435
Query: 594 PSGGYMEAF-----DYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGK 648
P G + ++ S+ F CE G +L G L C G+W+ + P+C+ + C
Sbjct: 436 PPKGLVRCAHSPIGEFTYKSSCAFSCEEGFELHGSTQLECTSQGQWTEEVPSCQVVKCSS 495
Query: 649 LPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSD 708
L +P +G G+V +++C + L G RTC WS P CE S+
Sbjct: 496 L-AVPGKINMSCSGEPVFGTVCKFACPEGWTLNGSAARTCGATGHWSGLLPTCEAPTESN 554
Query: 709 -PIVAEKSIVSVT 720
P+VA S ++
Sbjct: 555 IPLVAGLSAAGLS 567
Score = 165 bits (402), Expect = 6e-40
Identities = 143/570 (25%), Positives = 211/570 (37%), Gaps = 77/570 (13%)
Query: 236 SFDEARKQCQSHGGDLIHGFQGATSSFLTQELERRKAQLKTQLVWIGAQKEPGLTSRTWQ 295
++DEA CQ L+ +L L WIG +K + W
Sbjct: 32 TYDEASAYCQQRYTHLVAIQNKEEIEYLNSILS-----YSPSYYWIGIRK----VNNVWV 82
Query: 296 WVDGE---LVSKPSWGKDQPNNYNGEQNCVVLDGGRG---WLWNDVGCNLDYLHWICQYL 349
WV + +W +PNN +++CV + R +WND C+ L +C
Sbjct: 83 WVGTQKPLTEEAKNWAPGEPNNRQKDEDCVEIYIKREKDVGMWNDERCSKKKLA-LCYTA 141
Query: 350 PPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYV 409
T NT+ G+ +C E + CK D +SG + V
Sbjct: 142 ACT--------NTSCSGHG---------ECVETI-----NNYTCKCDPGFSGLKCE-QIV 178
Query: 410 NCGGLTPIEDGDVALID--NRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL 467
NC L E G + ++ + SC + C G W P C
Sbjct: 179 NCTALESPEHGSLVCSHPLGNFSYNSSCSISCDRGYLPSSMETMQCMSSGEWSAPIPACN 238
Query: 468 FDWCPDPPAVSNASVTVNGHKAG----SLASYTCENGHILSGSTSVTCTLGGAWSGVPPS 523
C +N V + + ++ CE G L G+ S+ CT G W P+
Sbjct: 239 VVECDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGNWDNEKPT 298
Query: 524 CKYVNCGTPTIHKGSFVLIN----GTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYD 579
CK V C + V + G T+ S FTCE + L G ++ C G+W+
Sbjct: 299 CKAVTCRAVRQPQNGSVRCSHSPAGEFTFKSSCNFTCEEGFMLQGPAQVECTTQGQWTQQ 358
Query: 580 IPSCELTSCPEPEVPSGGYMEAF-----DYYVHSTINFHCEAGHKLIGEPNLVCQQDGEW 634
IP CE C P GYM + S+ F CE G L G L C GEW
Sbjct: 359 IPVCEAFQCTALSNPERGYMNCLPSASGSFRYGSSCEFSCEQGFVLKGSKRLQCGPTGEW 418
Query: 635 SGDSPTCEYIDCGKLPTLPYGTMELLN---GTTHLGSVIQYSCTTNYRLVGPVRRTCTEE 691
+ PTCE + C + P G + + G S +SC + L G + CT +
Sbjct: 419 DNEKPTCEAVRCDAVHQPPKGLVRCAHSPIGEFTYKSSCAFSCEEGFELHGSTQLECTSQ 478
Query: 692 FQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKY 751
QW++ P C+ ++CS V K +S +G G + K+
Sbjct: 479 GQWTEEVPSCQVVKCSSLAVPGKINMSCSGEP--------------------VFGTVCKF 518
Query: 752 RCEKGYKVIGESLSTCEDNGQWSGTTPTCQ 781
C +G+ + G + TC G WSG PTC+
Sbjct: 519 ACPEGWTLNGSAARTCGATGHWSGLLPTCE 548
Score = 148 bits (358), Expect = 1e-34
Identities = 106/404 (26%), Positives = 166/404 (41%), Gaps = 38/404 (9%)
Query: 583 CE-LTSCPEPEVPSGGYMEAF----DYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGD 637
CE + +C E P G + ++ +S+ + C+ G+ + C GEWS
Sbjct: 174 CEQIVNCTALESPEHGSLVCSHPLGNFSYNSSCSISCDRGYLPSSMETMQCMSSGEWSAP 233
Query: 638 SPTCEYIDCGKLPTLPYGTMELLN--GTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWS 695
P C ++C + G +E G+ + + C + L+G CT W
Sbjct: 234 IPACNVVECDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGNWD 293
Query: 696 DSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEK 755
+ P C+ + C V + SV + G ++S N + CE+
Sbjct: 294 NEKPTCKAVTCR--AVRQPQNGSVRCSHSPAGEFTFKSSCN--------------FTCEE 337
Query: 756 GYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVT-LPS-NATF-YGATAFYQ 812
G+ + G + C GQW+ P C+ C E G + LPS + +F YG++ +
Sbjct: 338 GFMLQGPAQVECTTQGQWTQQIPVCEAFQCTALSNPERGYMNCLPSASGSFRYGSSCEFS 397
Query: 813 CDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIG---- 868
C++ + L+G R C G W E P C+ + C D Q G LV + IG
Sbjct: 398 CEQGFVLKGSKRLQCGPTGEWDNEKPTCEAVRC-DAVHQPPKG---LVRCAHSPIGEFTY 453
Query: 869 -GEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVIS-NGSTL 926
+ CE G+ L G C S+GQW VP C + C S GKI +S +G +
Sbjct: 454 KSSCAFSCEEGFELHGSTQLECTSQGQWTEEVPSCQVVKCSSLA--VPGKINMSCSGEPV 511
Query: 927 FGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCELATNEAV 970
FG+ ++ C + G R C G WSG P+CE T +
Sbjct: 512 FGTVCKFACPEGWTLNGSAARTCGATGHWSGLLPTCEAPTESNI 555
Score = 81.8 bits (193), Expect = 1e-14
Identities = 50/203 (24%), Positives = 79/203 (38%), Gaps = 6/203 (2%)
Query: 766 TCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTL--PSNATFYGATAFYQCDENWELEGVI 823
TC+ + +SG Q V+C E+G + P Y ++ CD + +
Sbjct: 162 TCKCDPGFSGLKCE-QIVNCTALESPEHGSLVCSHPLGNFSYNSSCSISCDRGYLPSSME 220
Query: 824 RRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKG 883
C +G WS P C + C + + + CE G+ L G
Sbjct: 221 TMQCMSSGEWSAPIPACNVVECDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMG 280
Query: 884 HQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISN---GSTLFGSSVEYYCLSQYQ 940
Q+ C S G W+ P C + CR+ +NG + S+ G F SS + C +
Sbjct: 281 AQSLQCTSSGNWDNEKPTCKAVTCRAVRQPQNGSVRCSHSPAGEFTFKSSCNFTCEEGFM 340
Query: 941 RVGPFLRKCLDDGRWSGEEPSCE 963
GP +C G+W+ + P CE
Sbjct: 341 LQGPAQVECTTQGQWTQQIPVCE 363
Score = 46.4 bits (105), Expect = 6e-04
Identities = 26/73 (35%), Positives = 35/73 (47%), Gaps = 3/73 (4%)
Query: 2 CGHPAVPPNARVS-IPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCG- 59
C P N V N + T ++C+EG+EL GA+ +CT G+W E P C
Sbjct: 242 CDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGNWDNEKPTCKA 301
Query: 60 -TNVAFRKPANQS 71
T A R+P N S
Sbjct: 302 VTCRAVRQPQNGS 314
Score = 44.0 bits (99), Expect = 0.003
Identities = 16/30 (53%), Positives = 21/30 (70%)
Query: 29 YECDEGYELFGARQRECTLRGDWTLEPPFC 58
+ C+EG+EL G+ Q ECT +G WT E P C
Sbjct: 459 FSCEEGFELHGSTQLECTSQGQWTEEVPSC 488
Score = 38.3 bits (85), Expect = 0.15
Identities = 14/30 (46%), Positives = 19/30 (63%)
Query: 29 YECDEGYELFGARQRECTLRGDWTLEPPFC 58
+ C+EG+ L G Q ECT +G WT + P C
Sbjct: 333 FTCEEGFMLQGPAQVECTTQGQWTQQIPVC 362
Score = 38.3 bits (85), Expect = 0.15
Identities = 20/58 (34%), Positives = 27/58 (46%), Gaps = 2/58 (3%)
Query: 1 RCGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
+C AVP +S E V GT+ + C EG+ L G+ R C G W+ P C
Sbjct: 492 KCSSLAVPGKINMSCSGEP--VFGTVCKFACPEGWTLNGSAARTCGATGHWSGLLPTC 547
Score = 33.5 bits (73), Expect = 4.2
Identities = 11/35 (31%), Positives = 21/35 (60%)
Query: 24 GTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
G+ + C++G+ L G+++ +C G+W E P C
Sbjct: 391 GSSCEFSCEQGFVLKGSKRLQCGPTGEWDNEKPTC 425
>BC131551-1|AAI31552.1| 610|Homo sapiens selectin E (endothelial
adhesion molecule 1) protein.
Length = 610
Score = 177 bits (432), Expect = 1e-43
Identities = 107/417 (25%), Positives = 181/417 (43%), Gaps = 33/417 (7%)
Query: 499 NGHILSGSTSVTCTLGGAWSGVPPSCKYVNC-GTPTIHKGSFVLIN--GTTTYGSIAQFT 555
+G + + TC +SG+ + VNC + GS V + G +Y S +
Sbjct: 151 HGECVETINNYTCKCDPGFSGLKCE-QIVNCTALESPEHGSLVCSHPLGNFSYNSSCSIS 209
Query: 556 CEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFD----YYVHSTIN 611
C+ Y + E + C G+WS IP+C + C P+ G++E F + ++T
Sbjct: 210 CDRGYLPSSMETMQCMSSGEWSAPIPACNVVECDAVTNPANGFVECFQNPGSFPWNTTCT 269
Query: 612 FHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLN---GTTHLGS 668
F CE G +L+G +L C G W + PTC+ + C + G++ + G S
Sbjct: 270 FDCEEGFELMGAQSLQCTSSGNWDNEKPTCKAVTCRAVRQPQNGSVRCSHSPAGEFTFKS 329
Query: 669 VIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGH 728
++C + L GP + CT + QW+ P CE +C+ +++ +R + +
Sbjct: 330 SCNFTCEEGFMLQGPAQVECTTQGQWTQQIPVCEAFQCT----------ALSNPERGYMN 379
Query: 729 TLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNP 788
L S ++R G+ ++ CE+G+ + G C G+W PTC+ V C
Sbjct: 380 CLPSAS------GSFRYGSSCEFSCEQGFVLKGSKRLQCGPTGEWDNEKPTCEAVRCDAV 433
Query: 789 GRIENGKVTL---PSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITC 845
+ G V P Y ++ + C+E +EL G + C G W+ E P C+ + C
Sbjct: 434 HQPPKGLVRCAHSPIGEFTYKSSCAFSCEEGFELHGSTQLECTSQGQWTEEVPSCQVVKC 493
Query: 846 PDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVC 902
S+ G + + G + C G+ L G RTC + G W+G +P C
Sbjct: 494 ---SSLAVPGKINMSCSGEPVFGTVCKFACPEGWTLNGSAARTCGATGHWSGLLPTC 547
Score = 173 bits (422), Expect = 2e-42
Identities = 105/373 (28%), Positives = 158/373 (42%), Gaps = 19/373 (5%)
Query: 365 LGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVAL 424
LGN + S C G++ ++ C G WS P+C V C +T +G V
Sbjct: 197 LGN-FSYNSSCSISCDRGYLPSSMETMQCMSSGEWSAPIPACNVVECDAVTNPANGFVEC 255
Query: 425 IDNRTTH--GARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASV 482
N + + C E F L+G C G WD E P C C N SV
Sbjct: 256 FQNPGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGNWDNEKPTCKAVTCRAVRQPQNGSV 315
Query: 483 TVNGHKAG-----SLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTIHKG 537
+ AG S ++TCE G +L G V CT G W+ P C+ C + +
Sbjct: 316 RCSHSPAGEFTFKSSCNFTCEEGFMLQGPAQVECTTQGQWTQQIPVCEAFQCTALSNPER 375
Query: 538 SFV----LINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEV 593
++ +G+ YGS +F+CE + L G++ L C G+W + P+CE C
Sbjct: 376 GYMNCLPSASGSFRYGSSCEFSCEQGFVLKGSKRLQCGPTGEWDNEKPTCEAVRCDAVHQ 435
Query: 594 PSGGYMEAF-----DYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGK 648
P G + ++ S+ F CE G +L G L C G+W+ + P+C+ + C
Sbjct: 436 PPKGLVRCAHSPIGEFTYKSSCAFSCEEGFELHGSTQLECTSQGQWTEEVPSCQVVKCSS 495
Query: 649 LPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSD 708
L +P +G G+V +++C + L G RTC WS P CE S+
Sbjct: 496 L-AVPGKINMSCSGEPVFGTVCKFACPEGWTLNGSAARTCGATGHWSGLLPTCEAPTESN 554
Query: 709 -PIVAEKSIVSVT 720
P+VA S ++
Sbjct: 555 IPLVAGLSAAGLS 567
Score = 165 bits (402), Expect = 6e-40
Identities = 143/570 (25%), Positives = 211/570 (37%), Gaps = 77/570 (13%)
Query: 236 SFDEARKQCQSHGGDLIHGFQGATSSFLTQELERRKAQLKTQLVWIGAQKEPGLTSRTWQ 295
++DEA CQ L+ +L L WIG +K + W
Sbjct: 32 TYDEASAYCQQRYTHLVAIQNKEEIEYLNSILS-----YSPSYYWIGIRK----VNNVWV 82
Query: 296 WVDGE---LVSKPSWGKDQPNNYNGEQNCVVLDGGRG---WLWNDVGCNLDYLHWICQYL 349
WV + +W +PNN +++CV + R +WND C+ L +C
Sbjct: 83 WVGTQKPLTEEAKNWAPGEPNNRQKDEDCVEIYIKREKDVGMWNDERCSKKKLA-LCYTA 141
Query: 350 PPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYV 409
T NT+ G+ +C E + CK D +SG + V
Sbjct: 142 ACT--------NTSCSGHG---------ECVETI-----NNYTCKCDPGFSGLKCE-QIV 178
Query: 410 NCGGLTPIEDGDVALID--NRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL 467
NC L E G + ++ + SC + C G W P C
Sbjct: 179 NCTALESPEHGSLVCSHPLGNFSYNSSCSISCDRGYLPSSMETMQCMSSGEWSAPIPACN 238
Query: 468 FDWCPDPPAVSNASVTVNGHKAG----SLASYTCENGHILSGSTSVTCTLGGAWSGVPPS 523
C +N V + + ++ CE G L G+ S+ CT G W P+
Sbjct: 239 VVECDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGNWDNEKPT 298
Query: 524 CKYVNCGTPTIHKGSFVLIN----GTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYD 579
CK V C + V + G T+ S FTCE + L G ++ C G+W+
Sbjct: 299 CKAVTCRAVRQPQNGSVRCSHSPAGEFTFKSSCNFTCEEGFMLQGPAQVECTTQGQWTQQ 358
Query: 580 IPSCELTSCPEPEVPSGGYMEAF-----DYYVHSTINFHCEAGHKLIGEPNLVCQQDGEW 634
IP CE C P GYM + S+ F CE G L G L C GEW
Sbjct: 359 IPVCEAFQCTALSNPERGYMNCLPSASGSFRYGSSCEFSCEQGFVLKGSKRLQCGPTGEW 418
Query: 635 SGDSPTCEYIDCGKLPTLPYGTMELLN---GTTHLGSVIQYSCTTNYRLVGPVRRTCTEE 691
+ PTCE + C + P G + + G S +SC + L G + CT +
Sbjct: 419 DNEKPTCEAVRCDAVHQPPKGLVRCAHSPIGEFTYKSSCAFSCEEGFELHGSTQLECTSQ 478
Query: 692 FQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKY 751
QW++ P C+ ++CS V K +S +G G + K+
Sbjct: 479 GQWTEEVPSCQVVKCSSLAVPGKINMSCSGEP--------------------VFGTVCKF 518
Query: 752 RCEKGYKVIGESLSTCEDNGQWSGTTPTCQ 781
C +G+ + G + TC G WSG PTC+
Sbjct: 519 ACPEGWTLNGSAARTCGATGHWSGLLPTCE 548
Score = 148 bits (358), Expect = 1e-34
Identities = 106/404 (26%), Positives = 166/404 (41%), Gaps = 38/404 (9%)
Query: 583 CE-LTSCPEPEVPSGGYMEAF----DYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGD 637
CE + +C E P G + ++ +S+ + C+ G+ + C GEWS
Sbjct: 174 CEQIVNCTALESPEHGSLVCSHPLGNFSYNSSCSISCDRGYLPSSMETMQCMSSGEWSAP 233
Query: 638 SPTCEYIDCGKLPTLPYGTMELLN--GTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWS 695
P C ++C + G +E G+ + + C + L+G CT W
Sbjct: 234 IPACNVVECDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGNWD 293
Query: 696 DSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEK 755
+ P C+ + C V + SV + G ++S N + CE+
Sbjct: 294 NEKPTCKAVTCR--AVRQPQNGSVRCSHSPAGEFTFKSSCN--------------FTCEE 337
Query: 756 GYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVT-LPS-NATF-YGATAFYQ 812
G+ + G + C GQW+ P C+ C E G + LPS + +F YG++ +
Sbjct: 338 GFMLQGPAQVECTTQGQWTQQIPVCEAFQCTALSNPERGYMNCLPSASGSFRYGSSCEFS 397
Query: 813 CDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIG---- 868
C++ + L+G R C G W E P C+ + C D Q G LV + IG
Sbjct: 398 CEQGFVLKGSKRLQCGPTGEWDNEKPTCEAVRC-DAVHQPPKG---LVRCAHSPIGEFTY 453
Query: 869 -GEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVIS-NGSTL 926
+ CE G+ L G C S+GQW VP C + C S GKI +S +G +
Sbjct: 454 KSSCAFSCEEGFELHGSTQLECTSQGQWTEEVPSCQVVKCSSLA--VPGKINMSCSGEPV 511
Query: 927 FGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCELATNEAV 970
FG+ ++ C + G R C G WSG P+CE T +
Sbjct: 512 FGTVCKFACPEGWTLNGSAARTCGATGHWSGLLPTCEAPTESNI 555
Score = 81.8 bits (193), Expect = 1e-14
Identities = 50/203 (24%), Positives = 79/203 (38%), Gaps = 6/203 (2%)
Query: 766 TCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTL--PSNATFYGATAFYQCDENWELEGVI 823
TC+ + +SG Q V+C E+G + P Y ++ CD + +
Sbjct: 162 TCKCDPGFSGLKCE-QIVNCTALESPEHGSLVCSHPLGNFSYNSSCSISCDRGYLPSSME 220
Query: 824 RRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKG 883
C +G WS P C + C + + + CE G+ L G
Sbjct: 221 TMQCMSSGEWSAPIPACNVVECDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMG 280
Query: 884 HQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISN---GSTLFGSSVEYYCLSQYQ 940
Q+ C S G W+ P C + CR+ +NG + S+ G F SS + C +
Sbjct: 281 AQSLQCTSSGNWDNEKPTCKAVTCRAVRQPQNGSVRCSHSPAGEFTFKSSCNFTCEEGFM 340
Query: 941 RVGPFLRKCLDDGRWSGEEPSCE 963
GP +C G+W+ + P CE
Sbjct: 341 LQGPAQVECTTQGQWTQQIPVCE 363
Score = 46.4 bits (105), Expect = 6e-04
Identities = 26/73 (35%), Positives = 35/73 (47%), Gaps = 3/73 (4%)
Query: 2 CGHPAVPPNARVS-IPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCG- 59
C P N V N + T ++C+EG+EL GA+ +CT G+W E P C
Sbjct: 242 CDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGNWDNEKPTCKA 301
Query: 60 -TNVAFRKPANQS 71
T A R+P N S
Sbjct: 302 VTCRAVRQPQNGS 314
Score = 44.0 bits (99), Expect = 0.003
Identities = 16/30 (53%), Positives = 21/30 (70%)
Query: 29 YECDEGYELFGARQRECTLRGDWTLEPPFC 58
+ C+EG+EL G+ Q ECT +G WT E P C
Sbjct: 459 FSCEEGFELHGSTQLECTSQGQWTEEVPSC 488
Score = 38.3 bits (85), Expect = 0.15
Identities = 14/30 (46%), Positives = 19/30 (63%)
Query: 29 YECDEGYELFGARQRECTLRGDWTLEPPFC 58
+ C+EG+ L G Q ECT +G WT + P C
Sbjct: 333 FTCEEGFMLQGPAQVECTTQGQWTQQIPVC 362
Score = 38.3 bits (85), Expect = 0.15
Identities = 20/58 (34%), Positives = 27/58 (46%), Gaps = 2/58 (3%)
Query: 1 RCGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
+C AVP +S E V GT+ + C EG+ L G+ R C G W+ P C
Sbjct: 492 KCSSLAVPGKINMSCSGEP--VFGTVCKFACPEGWTLNGSAARTCGATGHWSGLLPTC 547
Score = 33.5 bits (73), Expect = 4.2
Identities = 11/35 (31%), Positives = 21/35 (60%)
Query: 24 GTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
G+ + C++G+ L G+++ +C G+W E P C
Sbjct: 391 GSSCEFSCEQGFVLKGSKRLQCGPTGEWDNEKPTC 425
>AL021940-6|CAA17434.1| 610|Homo sapiens selectin E (endothelial
adhesion molecule 1) protein.
Length = 610
Score = 177 bits (432), Expect = 1e-43
Identities = 107/417 (25%), Positives = 181/417 (43%), Gaps = 33/417 (7%)
Query: 499 NGHILSGSTSVTCTLGGAWSGVPPSCKYVNC-GTPTIHKGSFVLIN--GTTTYGSIAQFT 555
+G + + TC +SG+ + VNC + GS V + G +Y S +
Sbjct: 151 HGECVETINNYTCKCDPGFSGLKCE-QIVNCTALESPEHGSLVCSHPLGNFSYNSSCSIS 209
Query: 556 CEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFD----YYVHSTIN 611
C+ Y + E + C G+WS IP+C + C P+ G++E F + ++T
Sbjct: 210 CDRGYLPSSMETMQCMSSGEWSAPIPACNVVECDAVTNPANGFVECFQNPGSFPWNTTCT 269
Query: 612 FHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLN---GTTHLGS 668
F CE G +L+G +L C G W + PTC+ + C + G++ + G S
Sbjct: 270 FDCEEGFELMGAQSLQCTSSGNWDNEKPTCKAVTCRAVRQPQNGSVRCSHSPAGEFTFKS 329
Query: 669 VIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGH 728
++C + L GP + CT + QW+ P CE +C+ +++ +R + +
Sbjct: 330 SCNFTCEEGFMLQGPAQVECTTQGQWTQQIPVCEAFQCT----------ALSNPERGYMN 379
Query: 729 TLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNP 788
L S ++R G+ ++ CE+G+ + G C G+W PTC+ V C
Sbjct: 380 CLPSAS------GSFRYGSSCEFSCEQGFVLKGSKRLQCGPTGEWDNEKPTCEAVRCDAV 433
Query: 789 GRIENGKVTL---PSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITC 845
+ G V P Y ++ + C+E +EL G + C G W+ E P C+ + C
Sbjct: 434 HQPPKGLVRCAHSPIGEFTYKSSCAFSCEEGFELHGSTQLECTSQGQWTEEVPSCQVVKC 493
Query: 846 PDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVC 902
S+ G + + G + C G+ L G RTC + G W+G +P C
Sbjct: 494 ---SSLAVPGKINMSCSGEPVFGTVCKFACPEGWTLNGSAARTCGATGHWSGLLPTC 547
Score = 173 bits (422), Expect = 2e-42
Identities = 105/373 (28%), Positives = 158/373 (42%), Gaps = 19/373 (5%)
Query: 365 LGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVAL 424
LGN + S C G++ ++ C G WS P+C V C +T +G V
Sbjct: 197 LGN-FSYNSSCSISCDRGYLPSSMETMQCMSSGEWSAPIPACNVVECDAVTNPANGFVEC 255
Query: 425 IDNRTTH--GARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASV 482
N + + C E F L+G C G WD E P C C N SV
Sbjct: 256 FQNPGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGNWDNEKPTCKAVTCRAVRQPQNGSV 315
Query: 483 TVNGHKAG-----SLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTIHKG 537
+ AG S ++TCE G +L G V CT G W+ P C+ C + +
Sbjct: 316 RCSHSPAGEFTFKSSCNFTCEEGFMLQGPAQVECTTQGQWTQQIPVCEAFQCTALSNPER 375
Query: 538 SFV----LINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEV 593
++ +G+ YGS +F+CE + L G++ L C G+W + P+CE C
Sbjct: 376 GYMNCLPSASGSFRYGSSCEFSCEQGFVLKGSKRLQCGPTGEWDNEKPTCEAVRCDAVHQ 435
Query: 594 PSGGYMEAF-----DYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGK 648
P G + ++ S+ F CE G +L G L C G+W+ + P+C+ + C
Sbjct: 436 PPKGLVRCAHSPIGEFTYKSSCAFSCEEGFELHGSTQLECTSQGQWTEEVPSCQVVKCSS 495
Query: 649 LPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSD 708
L +P +G G+V +++C + L G RTC WS P CE S+
Sbjct: 496 L-AVPGKINMSCSGEPVFGTVCKFACPEGWTLNGSAARTCGATGHWSGLLPTCEAPTESN 554
Query: 709 -PIVAEKSIVSVT 720
P+VA S ++
Sbjct: 555 IPLVAGLSAAGLS 567
Score = 165 bits (402), Expect = 6e-40
Identities = 143/570 (25%), Positives = 211/570 (37%), Gaps = 77/570 (13%)
Query: 236 SFDEARKQCQSHGGDLIHGFQGATSSFLTQELERRKAQLKTQLVWIGAQKEPGLTSRTWQ 295
++DEA CQ L+ +L L WIG +K + W
Sbjct: 32 TYDEASAYCQQRYTHLVAIQNKEEIEYLNSILS-----YSPSYYWIGIRK----VNNVWV 82
Query: 296 WVDGE---LVSKPSWGKDQPNNYNGEQNCVVLDGGRG---WLWNDVGCNLDYLHWICQYL 349
WV + +W +PNN +++CV + R +WND C+ L +C
Sbjct: 83 WVGTQKPLTEEAKNWAPGEPNNRQKDEDCVEIYIKREKDVGMWNDERCSKKKLA-LCYTA 141
Query: 350 PPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYV 409
T NT+ G+ +C E + CK D +SG + V
Sbjct: 142 ACT--------NTSCSGHG---------ECVETI-----NNYTCKCDPGFSGLKCE-QIV 178
Query: 410 NCGGLTPIEDGDVALID--NRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL 467
NC L E G + ++ + SC + C G W P C
Sbjct: 179 NCTALESPEHGSLVCSHPLGNFSYNSSCSISCDRGYLPSSMETMQCMSSGEWSAPIPACN 238
Query: 468 FDWCPDPPAVSNASVTVNGHKAG----SLASYTCENGHILSGSTSVTCTLGGAWSGVPPS 523
C +N V + + ++ CE G L G+ S+ CT G W P+
Sbjct: 239 VVECDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGNWDNEKPT 298
Query: 524 CKYVNCGTPTIHKGSFVLIN----GTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYD 579
CK V C + V + G T+ S FTCE + L G ++ C G+W+
Sbjct: 299 CKAVTCRAVRQPQNGSVRCSHSPAGEFTFKSSCNFTCEEGFMLQGPAQVECTTQGQWTQQ 358
Query: 580 IPSCELTSCPEPEVPSGGYMEAF-----DYYVHSTINFHCEAGHKLIGEPNLVCQQDGEW 634
IP CE C P GYM + S+ F CE G L G L C GEW
Sbjct: 359 IPVCEAFQCTALSNPERGYMNCLPSASGSFRYGSSCEFSCEQGFVLKGSKRLQCGPTGEW 418
Query: 635 SGDSPTCEYIDCGKLPTLPYGTMELLN---GTTHLGSVIQYSCTTNYRLVGPVRRTCTEE 691
+ PTCE + C + P G + + G S +SC + L G + CT +
Sbjct: 419 DNEKPTCEAVRCDAVHQPPKGLVRCAHSPIGEFTYKSSCAFSCEEGFELHGSTQLECTSQ 478
Query: 692 FQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKY 751
QW++ P C+ ++CS V K +S +G G + K+
Sbjct: 479 GQWTEEVPSCQVVKCSSLAVPGKINMSCSGEP--------------------VFGTVCKF 518
Query: 752 RCEKGYKVIGESLSTCEDNGQWSGTTPTCQ 781
C +G+ + G + TC G WSG PTC+
Sbjct: 519 ACPEGWTLNGSAARTCGATGHWSGLLPTCE 548
Score = 148 bits (358), Expect = 1e-34
Identities = 106/404 (26%), Positives = 166/404 (41%), Gaps = 38/404 (9%)
Query: 583 CE-LTSCPEPEVPSGGYMEAF----DYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGD 637
CE + +C E P G + ++ +S+ + C+ G+ + C GEWS
Sbjct: 174 CEQIVNCTALESPEHGSLVCSHPLGNFSYNSSCSISCDRGYLPSSMETMQCMSSGEWSAP 233
Query: 638 SPTCEYIDCGKLPTLPYGTMELLN--GTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWS 695
P C ++C + G +E G+ + + C + L+G CT W
Sbjct: 234 IPACNVVECDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGNWD 293
Query: 696 DSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEK 755
+ P C+ + C V + SV + G ++S N + CE+
Sbjct: 294 NEKPTCKAVTCR--AVRQPQNGSVRCSHSPAGEFTFKSSCN--------------FTCEE 337
Query: 756 GYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVT-LPS-NATF-YGATAFYQ 812
G+ + G + C GQW+ P C+ C E G + LPS + +F YG++ +
Sbjct: 338 GFMLQGPAQVECTTQGQWTQQIPVCEAFQCTALSNPERGYMNCLPSASGSFRYGSSCEFS 397
Query: 813 CDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIG---- 868
C++ + L+G R C G W E P C+ + C D Q G LV + IG
Sbjct: 398 CEQGFVLKGSKRLQCGPTGEWDNEKPTCEAVRC-DAVHQPPKG---LVRCAHSPIGEFTY 453
Query: 869 -GEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVIS-NGSTL 926
+ CE G+ L G C S+GQW VP C + C S GKI +S +G +
Sbjct: 454 KSSCAFSCEEGFELHGSTQLECTSQGQWTEEVPSCQVVKCSSLA--VPGKINMSCSGEPV 511
Query: 927 FGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCELATNEAV 970
FG+ ++ C + G R C G WSG P+CE T +
Sbjct: 512 FGTVCKFACPEGWTLNGSAARTCGATGHWSGLLPTCEAPTESNI 555
Score = 81.8 bits (193), Expect = 1e-14
Identities = 50/203 (24%), Positives = 79/203 (38%), Gaps = 6/203 (2%)
Query: 766 TCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTL--PSNATFYGATAFYQCDENWELEGVI 823
TC+ + +SG Q V+C E+G + P Y ++ CD + +
Sbjct: 162 TCKCDPGFSGLKCE-QIVNCTALESPEHGSLVCSHPLGNFSYNSSCSISCDRGYLPSSME 220
Query: 824 RRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKG 883
C +G WS P C + C + + + CE G+ L G
Sbjct: 221 TMQCMSSGEWSAPIPACNVVECDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMG 280
Query: 884 HQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISN---GSTLFGSSVEYYCLSQYQ 940
Q+ C S G W+ P C + CR+ +NG + S+ G F SS + C +
Sbjct: 281 AQSLQCTSSGNWDNEKPTCKAVTCRAVRQPQNGSVRCSHSPAGEFTFKSSCNFTCEEGFM 340
Query: 941 RVGPFLRKCLDDGRWSGEEPSCE 963
GP +C G+W+ + P CE
Sbjct: 341 LQGPAQVECTTQGQWTQQIPVCE 363
Score = 46.4 bits (105), Expect = 6e-04
Identities = 26/73 (35%), Positives = 35/73 (47%), Gaps = 3/73 (4%)
Query: 2 CGHPAVPPNARVS-IPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCG- 59
C P N V N + T ++C+EG+EL GA+ +CT G+W E P C
Sbjct: 242 CDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGNWDNEKPTCKA 301
Query: 60 -TNVAFRKPANQS 71
T A R+P N S
Sbjct: 302 VTCRAVRQPQNGS 314
Score = 44.0 bits (99), Expect = 0.003
Identities = 16/30 (53%), Positives = 21/30 (70%)
Query: 29 YECDEGYELFGARQRECTLRGDWTLEPPFC 58
+ C+EG+EL G+ Q ECT +G WT E P C
Sbjct: 459 FSCEEGFELHGSTQLECTSQGQWTEEVPSC 488
Score = 38.3 bits (85), Expect = 0.15
Identities = 14/30 (46%), Positives = 19/30 (63%)
Query: 29 YECDEGYELFGARQRECTLRGDWTLEPPFC 58
+ C+EG+ L G Q ECT +G WT + P C
Sbjct: 333 FTCEEGFMLQGPAQVECTTQGQWTQQIPVC 362
Score = 38.3 bits (85), Expect = 0.15
Identities = 20/58 (34%), Positives = 27/58 (46%), Gaps = 2/58 (3%)
Query: 1 RCGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
+C AVP +S E V GT+ + C EG+ L G+ R C G W+ P C
Sbjct: 492 KCSSLAVPGKINMSCSGEP--VFGTVCKFACPEGWTLNGSAARTCGATGHWSGLLPTC 547
Score = 33.5 bits (73), Expect = 4.2
Identities = 11/35 (31%), Positives = 21/35 (60%)
Query: 24 GTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
G+ + C++G+ L G+++ +C G+W E P C
Sbjct: 391 GSSCEFSCEQGFVLKGSKRLQCGPTGEWDNEKPTC 425
>AF540378-1|AAN01237.1| 610|Homo sapiens selectin E (endothelial
adhesion molecule 1) protein.
Length = 610
Score = 177 bits (432), Expect = 1e-43
Identities = 107/417 (25%), Positives = 181/417 (43%), Gaps = 33/417 (7%)
Query: 499 NGHILSGSTSVTCTLGGAWSGVPPSCKYVNC-GTPTIHKGSFVLIN--GTTTYGSIAQFT 555
+G + + TC +SG+ + VNC + GS V + G +Y S +
Sbjct: 151 HGECVETINNYTCKCDPGFSGLKCE-QIVNCTALESPEHGSLVCSHPLGNFSYNSSCSIS 209
Query: 556 CEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFD----YYVHSTIN 611
C+ Y + E + C G+WS IP+C + C P+ G++E F + ++T
Sbjct: 210 CDRGYLPSSMETMQCMSSGEWSAPIPACNVVECDAVTNPANGFVECFQNPGSFPWNTTCT 269
Query: 612 FHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLN---GTTHLGS 668
F CE G +L+G +L C G W + PTC+ + C + G++ + G S
Sbjct: 270 FDCEEGFELMGAQSLQCTSSGNWDNEKPTCKAVTCRAVRQPQNGSVRCSHSPAGEFTFKS 329
Query: 669 VIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGH 728
++C + L GP + CT + QW+ P CE +C+ +++ +R + +
Sbjct: 330 SCNFTCEEGFMLQGPAQVECTTQGQWTQQIPVCEAFQCT----------ALSNPERGYMN 379
Query: 729 TLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNP 788
L S ++R G+ ++ CE+G+ + G C G+W PTC+ V C
Sbjct: 380 CLPSAS------GSFRYGSSCEFSCEQGFVLKGSKRLQCGPTGEWDNEKPTCEAVRCDAV 433
Query: 789 GRIENGKVTL---PSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITC 845
+ G V P Y ++ + C+E +EL G + C G W+ E P C+ + C
Sbjct: 434 HQPPKGLVRCAHSPIGEFTYKSSCAFSCEEGFELHGSTQLECTSQGQWTEEVPSCQVVKC 493
Query: 846 PDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVC 902
S+ G + + G + C G+ L G RTC + G W+G +P C
Sbjct: 494 ---SSLAVPGKINMSCSGEPVFGTVCKFACPEGWTLNGSAARTCGATGHWSGLLPTC 547
Score = 173 bits (422), Expect = 2e-42
Identities = 105/373 (28%), Positives = 158/373 (42%), Gaps = 19/373 (5%)
Query: 365 LGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVAL 424
LGN + S C G++ ++ C G WS P+C V C +T +G V
Sbjct: 197 LGN-FSYNSSCSISCDRGYLPSSMETMQCMSSGEWSAPIPACNVVECDAVTNPANGFVEC 255
Query: 425 IDNRTTH--GARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASV 482
N + + C E F L+G C G WD E P C C N SV
Sbjct: 256 FQNPGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGNWDNEKPTCKAVTCRAVRQPQNGSV 315
Query: 483 TVNGHKAG-----SLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTIHKG 537
+ AG S ++TCE G +L G V CT G W+ P C+ C + +
Sbjct: 316 RCSHSPAGEFTFKSSCNFTCEEGFMLQGPAQVECTTQGQWTQQIPVCEAFQCTALSNPER 375
Query: 538 SFV----LINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEV 593
++ +G+ YGS +F+CE + L G++ L C G+W + P+CE C
Sbjct: 376 GYMNCLPSASGSFRYGSSCEFSCEQGFVLKGSKRLQCGPTGEWDNEKPTCEAVRCDAVHQ 435
Query: 594 PSGGYMEAF-----DYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGK 648
P G + ++ S+ F CE G +L G L C G+W+ + P+C+ + C
Sbjct: 436 PPKGLVRCAHSPIGEFTYKSSCAFSCEEGFELHGSTQLECTSQGQWTEEVPSCQVVKCSS 495
Query: 649 LPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSD 708
L +P +G G+V +++C + L G RTC WS P CE S+
Sbjct: 496 L-AVPGKINMSCSGEPVFGTVCKFACPEGWTLNGSAARTCGATGHWSGLLPTCEAPTESN 554
Query: 709 -PIVAEKSIVSVT 720
P+VA S ++
Sbjct: 555 IPLVAGLSAAGLS 567
Score = 165 bits (402), Expect = 6e-40
Identities = 143/570 (25%), Positives = 211/570 (37%), Gaps = 77/570 (13%)
Query: 236 SFDEARKQCQSHGGDLIHGFQGATSSFLTQELERRKAQLKTQLVWIGAQKEPGLTSRTWQ 295
++DEA CQ L+ +L L WIG +K + W
Sbjct: 32 TYDEASAYCQQRYTHLVAIQNKEEIEYLNSILS-----YSPSYYWIGIRK----VNNVWV 82
Query: 296 WVDGE---LVSKPSWGKDQPNNYNGEQNCVVLDGGRG---WLWNDVGCNLDYLHWICQYL 349
WV + +W +PNN +++CV + R +WND C+ L +C
Sbjct: 83 WVGTQKPLTEEAKNWAPGEPNNRQKDEDCVEIYIKREKDVGMWNDERCSKKKLA-LCYTA 141
Query: 350 PPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYV 409
T NT+ G+ +C E + CK D +SG + V
Sbjct: 142 ACT--------NTSCSGHG---------ECVETI-----NNYTCKCDPGFSGLKCE-QIV 178
Query: 410 NCGGLTPIEDGDVALID--NRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL 467
NC L E G + ++ + SC + C G W P C
Sbjct: 179 NCTALESPEHGSLVCSHPLGNFSYNSSCSISCDRGYLPSSMETMQCMSSGEWSAPIPACN 238
Query: 468 FDWCPDPPAVSNASVTVNGHKAG----SLASYTCENGHILSGSTSVTCTLGGAWSGVPPS 523
C +N V + + ++ CE G L G+ S+ CT G W P+
Sbjct: 239 VVECDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGNWDNEKPT 298
Query: 524 CKYVNCGTPTIHKGSFVLIN----GTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYD 579
CK V C + V + G T+ S FTCE + L G ++ C G+W+
Sbjct: 299 CKAVTCRAVRQPQNGSVRCSHSPAGEFTFKSSCNFTCEEGFMLQGPAQVECTTQGQWTQQ 358
Query: 580 IPSCELTSCPEPEVPSGGYMEAF-----DYYVHSTINFHCEAGHKLIGEPNLVCQQDGEW 634
IP CE C P GYM + S+ F CE G L G L C GEW
Sbjct: 359 IPVCEAFQCTALSNPERGYMNCLPSASGSFRYGSSCEFSCEQGFVLKGSKRLQCGPTGEW 418
Query: 635 SGDSPTCEYIDCGKLPTLPYGTMELLN---GTTHLGSVIQYSCTTNYRLVGPVRRTCTEE 691
+ PTCE + C + P G + + G S +SC + L G + CT +
Sbjct: 419 DNEKPTCEAVRCDAVHQPPKGLVRCAHSPIGEFTYKSSCAFSCEEGFELHGSTQLECTSQ 478
Query: 692 FQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKY 751
QW++ P C+ ++CS V K +S +G G + K+
Sbjct: 479 GQWTEEVPSCQVVKCSSLAVPGKINMSCSGEP--------------------VFGTVCKF 518
Query: 752 RCEKGYKVIGESLSTCEDNGQWSGTTPTCQ 781
C +G+ + G + TC G WSG PTC+
Sbjct: 519 ACPEGWTLNGSAARTCGATGHWSGLLPTCE 548
Score = 148 bits (358), Expect = 1e-34
Identities = 106/404 (26%), Positives = 166/404 (41%), Gaps = 38/404 (9%)
Query: 583 CE-LTSCPEPEVPSGGYMEAF----DYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGD 637
CE + +C E P G + ++ +S+ + C+ G+ + C GEWS
Sbjct: 174 CEQIVNCTALESPEHGSLVCSHPLGNFSYNSSCSISCDRGYLPSSMETMQCMSSGEWSAP 233
Query: 638 SPTCEYIDCGKLPTLPYGTMELLN--GTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWS 695
P C ++C + G +E G+ + + C + L+G CT W
Sbjct: 234 IPACNVVECDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGNWD 293
Query: 696 DSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEK 755
+ P C+ + C V + SV + G ++S N + CE+
Sbjct: 294 NEKPTCKAVTCR--AVRQPQNGSVRCSHSPAGEFTFKSSCN--------------FTCEE 337
Query: 756 GYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVT-LPS-NATF-YGATAFYQ 812
G+ + G + C GQW+ P C+ C E G + LPS + +F YG++ +
Sbjct: 338 GFMLQGPAQVECTTQGQWTQQIPVCEAFQCTALSNPERGYMNCLPSASGSFRYGSSCEFS 397
Query: 813 CDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIG---- 868
C++ + L+G R C G W E P C+ + C D Q G LV + IG
Sbjct: 398 CEQGFVLKGSKRLQCGPTGEWDNEKPTCEAVRC-DAVHQPPKG---LVRCAHSPIGEFTY 453
Query: 869 -GEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVIS-NGSTL 926
+ CE G+ L G C S+GQW VP C + C S GKI +S +G +
Sbjct: 454 KSSCAFSCEEGFELHGSTQLECTSQGQWTEEVPSCQVVKCSSLA--VPGKINMSCSGEPV 511
Query: 927 FGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCELATNEAV 970
FG+ ++ C + G R C G WSG P+CE T +
Sbjct: 512 FGTVCKFACPEGWTLNGSAARTCGATGHWSGLLPTCEAPTESNI 555
Score = 81.8 bits (193), Expect = 1e-14
Identities = 50/203 (24%), Positives = 79/203 (38%), Gaps = 6/203 (2%)
Query: 766 TCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTL--PSNATFYGATAFYQCDENWELEGVI 823
TC+ + +SG Q V+C E+G + P Y ++ CD + +
Sbjct: 162 TCKCDPGFSGLKCE-QIVNCTALESPEHGSLVCSHPLGNFSYNSSCSISCDRGYLPSSME 220
Query: 824 RRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKG 883
C +G WS P C + C + + + CE G+ L G
Sbjct: 221 TMQCMSSGEWSAPIPACNVVECDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMG 280
Query: 884 HQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISN---GSTLFGSSVEYYCLSQYQ 940
Q+ C S G W+ P C + CR+ +NG + S+ G F SS + C +
Sbjct: 281 AQSLQCTSSGNWDNEKPTCKAVTCRAVRQPQNGSVRCSHSPAGEFTFKSSCNFTCEEGFM 340
Query: 941 RVGPFLRKCLDDGRWSGEEPSCE 963
GP +C G+W+ + P CE
Sbjct: 341 LQGPAQVECTTQGQWTQQIPVCE 363
Score = 46.4 bits (105), Expect = 6e-04
Identities = 26/73 (35%), Positives = 35/73 (47%), Gaps = 3/73 (4%)
Query: 2 CGHPAVPPNARVS-IPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCG- 59
C P N V N + T ++C+EG+EL GA+ +CT G+W E P C
Sbjct: 242 CDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGNWDNEKPTCKA 301
Query: 60 -TNVAFRKPANQS 71
T A R+P N S
Sbjct: 302 VTCRAVRQPQNGS 314
Score = 44.0 bits (99), Expect = 0.003
Identities = 16/30 (53%), Positives = 21/30 (70%)
Query: 29 YECDEGYELFGARQRECTLRGDWTLEPPFC 58
+ C+EG+EL G+ Q ECT +G WT E P C
Sbjct: 459 FSCEEGFELHGSTQLECTSQGQWTEEVPSC 488
Score = 38.3 bits (85), Expect = 0.15
Identities = 14/30 (46%), Positives = 19/30 (63%)
Query: 29 YECDEGYELFGARQRECTLRGDWTLEPPFC 58
+ C+EG+ L G Q ECT +G WT + P C
Sbjct: 333 FTCEEGFMLQGPAQVECTTQGQWTQQIPVC 362
Score = 38.3 bits (85), Expect = 0.15
Identities = 20/58 (34%), Positives = 27/58 (46%), Gaps = 2/58 (3%)
Query: 1 RCGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
+C AVP +S E V GT+ + C EG+ L G+ R C G W+ P C
Sbjct: 492 KCSSLAVPGKINMSCSGEP--VFGTVCKFACPEGWTLNGSAARTCGATGHWSGLLPTC 547
Score = 33.5 bits (73), Expect = 4.2
Identities = 11/35 (31%), Positives = 21/35 (60%)
Query: 24 GTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
G+ + C++G+ L G+++ +C G+W E P C
Sbjct: 391 GSSCEFSCEQGFVLKGSKRLQCGPTGEWDNEKPTC 425
>M24736-1|AAA52376.1| 610|Homo sapiens endothelial leukocyte
adhesion molecule 1 protein.
Length = 610
Score = 177 bits (430), Expect = 2e-43
Identities = 107/417 (25%), Positives = 181/417 (43%), Gaps = 33/417 (7%)
Query: 499 NGHILSGSTSVTCTLGGAWSGVPPSCKYVNC-GTPTIHKGSFVLIN--GTTTYGSIAQFT 555
+G + + TC +SG+ + VNC + GS V + G +Y S +
Sbjct: 151 HGECVETINNYTCKCDPGFSGLKCE-QIVNCTALESPEHGSLVCSHPLGNFSYNSSCSIS 209
Query: 556 CEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFD----YYVHSTIN 611
C+ Y + E + C G+WS IP+C + C P+ G++E F + ++T
Sbjct: 210 CDRGYLPSSMETMQCMSSGEWSAPIPACNVVECDAVTNPANGFVECFQNPGSFPWNTTCT 269
Query: 612 FHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLN---GTTHLGS 668
F CE G +L+G +L C G W + PTC+ + C + G++ + G S
Sbjct: 270 FDCEEGFELMGAQSLQCTSSGNWDNEKPTCKAVTCRAVRQPQNGSVRCSHSPAGEFTFKS 329
Query: 669 VIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGH 728
++C + L GP + CT + QW+ P CE +C+ +++ +R + +
Sbjct: 330 SCNFTCEEGFMLQGPAQVECTTQGQWTQQIPVCEAFQCT----------ALSNPERGYMN 379
Query: 729 TLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNP 788
L S ++R G+ ++ CE+G+ + G C G+W PTC+ V C
Sbjct: 380 CLPSAS------GSFRYGSSCEFSCEQGFVLKGSKRLQCGPTGEWDNEKPTCEAVRCDAV 433
Query: 789 GRIENGKVTL---PSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITC 845
+ G V P Y ++ + C+E +EL G + C G W+ E P C+ + C
Sbjct: 434 HQPPKGLVRCAHSPIGEFTYKSSCAFSCEEGFELYGSTQLECTSQGQWTEEVPSCQVVKC 493
Query: 846 PDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVC 902
S+ G + + G + C G+ L G RTC + G W+G +P C
Sbjct: 494 ---SSLAVPGKINMSCSGEPVFGTVCKFACPEGWTLNGSAARTCGATGHWSGLLPTC 547
Score = 174 bits (424), Expect = 1e-42
Identities = 105/373 (28%), Positives = 158/373 (42%), Gaps = 19/373 (5%)
Query: 365 LGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVAL 424
LGN + S C G++ ++ C G WS P+C V C +T +G V
Sbjct: 197 LGN-FSYNSSCSISCDRGYLPSSMETMQCMSSGEWSAPIPACNVVECDAVTNPANGFVEC 255
Query: 425 IDNRTTH--GARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASV 482
N + + C E F L+G C G WD E P C C N SV
Sbjct: 256 FQNPGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGNWDNEKPTCKAVTCRAVRQPQNGSV 315
Query: 483 TVNGHKAG-----SLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTIHKG 537
+ AG S ++TCE G +L G V CT G W+ P C+ C + +
Sbjct: 316 RCSHSPAGEFTFKSSCNFTCEEGFMLQGPAQVECTTQGQWTQQIPVCEAFQCTALSNPER 375
Query: 538 SFV----LINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEV 593
++ +G+ YGS +F+CE + L G++ L C G+W + P+CE C
Sbjct: 376 GYMNCLPSASGSFRYGSSCEFSCEQGFVLKGSKRLQCGPTGEWDNEKPTCEAVRCDAVHQ 435
Query: 594 PSGGYMEAF-----DYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGK 648
P G + ++ S+ F CE G +L G L C G+W+ + P+C+ + C
Sbjct: 436 PPKGLVRCAHSPIGEFTYKSSCAFSCEEGFELYGSTQLECTSQGQWTEEVPSCQVVKCSS 495
Query: 649 LPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSD 708
L +P +G G+V +++C + L G RTC WS P CE S+
Sbjct: 496 L-AVPGKINMSCSGEPVFGTVCKFACPEGWTLNGSAARTCGATGHWSGLLPTCEAPTESN 554
Query: 709 -PIVAEKSIVSVT 720
P+VA S ++
Sbjct: 555 IPLVAGLSAAGLS 567
Score = 166 bits (404), Expect = 3e-40
Identities = 143/570 (25%), Positives = 211/570 (37%), Gaps = 77/570 (13%)
Query: 236 SFDEARKQCQSHGGDLIHGFQGATSSFLTQELERRKAQLKTQLVWIGAQKEPGLTSRTWQ 295
++DEA CQ L+ +L L WIG +K + W
Sbjct: 32 TYDEASAYCQQRYTHLVAIQNKEEIEYLNSILS-----YSPSYYWIGIRK----VNNVWV 82
Query: 296 WVDGE---LVSKPSWGKDQPNNYNGEQNCVVLDGGRG---WLWNDVGCNLDYLHWICQYL 349
WV + +W +PNN +++CV + R +WND C+ L +C
Sbjct: 83 WVGTQKPLTEEAKNWAPGEPNNRQKDEDCVEIYIKREKDVGMWNDERCSKKKLA-LCYTA 141
Query: 350 PPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYV 409
T NT+ G+ +C E + CK D +SG + V
Sbjct: 142 ACT--------NTSCSGHG---------ECVETI-----NNYTCKCDPGFSGLKCE-QIV 178
Query: 410 NCGGLTPIEDGDVALID--NRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL 467
NC L E G + ++ + SC + C G W P C
Sbjct: 179 NCTALESPEHGSLVCSHPLGNFSYNSSCSISCDRGYLPSSMETMQCMSSGEWSAPIPACN 238
Query: 468 FDWCPDPPAVSNASVTVNGHKAG----SLASYTCENGHILSGSTSVTCTLGGAWSGVPPS 523
C +N V + + ++ CE G L G+ S+ CT G W P+
Sbjct: 239 VVECDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGNWDNEKPT 298
Query: 524 CKYVNCGTPTIHKGSFVLIN----GTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYD 579
CK V C + V + G T+ S FTCE + L G ++ C G+W+
Sbjct: 299 CKAVTCRAVRQPQNGSVRCSHSPAGEFTFKSSCNFTCEEGFMLQGPAQVECTTQGQWTQQ 358
Query: 580 IPSCELTSCPEPEVPSGGYMEAF-----DYYVHSTINFHCEAGHKLIGEPNLVCQQDGEW 634
IP CE C P GYM + S+ F CE G L G L C GEW
Sbjct: 359 IPVCEAFQCTALSNPERGYMNCLPSASGSFRYGSSCEFSCEQGFVLKGSKRLQCGPTGEW 418
Query: 635 SGDSPTCEYIDCGKLPTLPYGTMELLN---GTTHLGSVIQYSCTTNYRLVGPVRRTCTEE 691
+ PTCE + C + P G + + G S +SC + L G + CT +
Sbjct: 419 DNEKPTCEAVRCDAVHQPPKGLVRCAHSPIGEFTYKSSCAFSCEEGFELYGSTQLECTSQ 478
Query: 692 FQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKY 751
QW++ P C+ ++CS V K +S +G G + K+
Sbjct: 479 GQWTEEVPSCQVVKCSSLAVPGKINMSCSGEP--------------------VFGTVCKF 518
Query: 752 RCEKGYKVIGESLSTCEDNGQWSGTTPTCQ 781
C +G+ + G + TC G WSG PTC+
Sbjct: 519 ACPEGWTLNGSAARTCGATGHWSGLLPTCE 548
Score = 147 bits (357), Expect = 2e-34
Identities = 106/404 (26%), Positives = 166/404 (41%), Gaps = 38/404 (9%)
Query: 583 CE-LTSCPEPEVPSGGYMEAF----DYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGD 637
CE + +C E P G + ++ +S+ + C+ G+ + C GEWS
Sbjct: 174 CEQIVNCTALESPEHGSLVCSHPLGNFSYNSSCSISCDRGYLPSSMETMQCMSSGEWSAP 233
Query: 638 SPTCEYIDCGKLPTLPYGTMELLN--GTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWS 695
P C ++C + G +E G+ + + C + L+G CT W
Sbjct: 234 IPACNVVECDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGNWD 293
Query: 696 DSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEK 755
+ P C+ + C V + SV + G ++S N + CE+
Sbjct: 294 NEKPTCKAVTCR--AVRQPQNGSVRCSHSPAGEFTFKSSCN--------------FTCEE 337
Query: 756 GYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVT-LPS-NATF-YGATAFYQ 812
G+ + G + C GQW+ P C+ C E G + LPS + +F YG++ +
Sbjct: 338 GFMLQGPAQVECTTQGQWTQQIPVCEAFQCTALSNPERGYMNCLPSASGSFRYGSSCEFS 397
Query: 813 CDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIG---- 868
C++ + L+G R C G W E P C+ + C D Q G LV + IG
Sbjct: 398 CEQGFVLKGSKRLQCGPTGEWDNEKPTCEAVRC-DAVHQPPKG---LVRCAHSPIGEFTY 453
Query: 869 -GEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVIS-NGSTL 926
+ CE G+ L G C S+GQW VP C + C S GKI +S +G +
Sbjct: 454 KSSCAFSCEEGFELYGSTQLECTSQGQWTEEVPSCQVVKCSSLA--VPGKINMSCSGEPV 511
Query: 927 FGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCELATNEAV 970
FG+ ++ C + G R C G WSG P+CE T +
Sbjct: 512 FGTVCKFACPEGWTLNGSAARTCGATGHWSGLLPTCEAPTESNI 555
Score = 81.8 bits (193), Expect = 1e-14
Identities = 50/203 (24%), Positives = 79/203 (38%), Gaps = 6/203 (2%)
Query: 766 TCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTL--PSNATFYGATAFYQCDENWELEGVI 823
TC+ + +SG Q V+C E+G + P Y ++ CD + +
Sbjct: 162 TCKCDPGFSGLKCE-QIVNCTALESPEHGSLVCSHPLGNFSYNSSCSISCDRGYLPSSME 220
Query: 824 RRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKG 883
C +G WS P C + C + + + CE G+ L G
Sbjct: 221 TMQCMSSGEWSAPIPACNVVECDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMG 280
Query: 884 HQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISN---GSTLFGSSVEYYCLSQYQ 940
Q+ C S G W+ P C + CR+ +NG + S+ G F SS + C +
Sbjct: 281 AQSLQCTSSGNWDNEKPTCKAVTCRAVRQPQNGSVRCSHSPAGEFTFKSSCNFTCEEGFM 340
Query: 941 RVGPFLRKCLDDGRWSGEEPSCE 963
GP +C G+W+ + P CE
Sbjct: 341 LQGPAQVECTTQGQWTQQIPVCE 363
Score = 46.4 bits (105), Expect = 6e-04
Identities = 26/73 (35%), Positives = 35/73 (47%), Gaps = 3/73 (4%)
Query: 2 CGHPAVPPNARVS-IPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCG- 59
C P N V N + T ++C+EG+EL GA+ +CT G+W E P C
Sbjct: 242 CDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGNWDNEKPTCKA 301
Query: 60 -TNVAFRKPANQS 71
T A R+P N S
Sbjct: 302 VTCRAVRQPQNGS 314
Score = 45.6 bits (103), Expect = 0.001
Identities = 16/30 (53%), Positives = 22/30 (73%)
Query: 29 YECDEGYELFGARQRECTLRGDWTLEPPFC 58
+ C+EG+EL+G+ Q ECT +G WT E P C
Sbjct: 459 FSCEEGFELYGSTQLECTSQGQWTEEVPSC 488
Score = 38.3 bits (85), Expect = 0.15
Identities = 14/30 (46%), Positives = 19/30 (63%)
Query: 29 YECDEGYELFGARQRECTLRGDWTLEPPFC 58
+ C+EG+ L G Q ECT +G WT + P C
Sbjct: 333 FTCEEGFMLQGPAQVECTTQGQWTQQIPVC 362
Score = 38.3 bits (85), Expect = 0.15
Identities = 20/58 (34%), Positives = 27/58 (46%), Gaps = 2/58 (3%)
Query: 1 RCGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
+C AVP +S E V GT+ + C EG+ L G+ R C G W+ P C
Sbjct: 492 KCSSLAVPGKINMSCSGEP--VFGTVCKFACPEGWTLNGSAARTCGATGHWSGLLPTC 547
Score = 33.5 bits (73), Expect = 4.2
Identities = 11/35 (31%), Positives = 21/35 (60%)
Query: 24 GTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
G+ + C++G+ L G+++ +C G+W E P C
Sbjct: 391 GSSCEFSCEQGFVLKGSKRLQCGPTGEWDNEKPTC 425
>X02865-1|CAA26617.1| 518|Homo sapiens protein ( Human mRNA
fragment for C4b-binding protein (C4BP). ).
Length = 518
Score = 176 bits (429), Expect = 3e-43
Identities = 138/497 (27%), Positives = 218/497 (43%), Gaps = 50/497 (10%)
Query: 496 TCENGHILSGST-SVTCTLGGAWSGVPPSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQF 554
TC G++ S ST ++TC G W C Y C P + V I ++GS +F
Sbjct: 1 TCLPGYVRSHSTQTLTCNSDGEWV-YNTFCIYKRCRHPGELRNGQVEIKTDLSFGSQIEF 59
Query: 555 TCEPDYWLNGAEELVC---NRDGKWSYDIPSCELTSC-PEPEVPSGGYMEAFDYYVHS-T 609
+C ++L G+ C +R WS+ +P CE+ C P P++ +G + ++Y + +
Sbjct: 60 SCSEGFFLIGSTTSRCEVQDRGVGWSHPLPQCEIVKCKPPPDIRNGRHSGEENFYAYGFS 119
Query: 610 INFHCEAGHKLIGEPNLVCQQDGE----WSGDSPTCEYIDCGKLPTLPYGTMELLNGTTH 665
+ + C+ L+G ++ C + E W PTCE I C K P + +G M G +
Sbjct: 120 VTYSCDPRFSLLGHASISCTVENETIGVWRPSPPTCEKITCRK-PDVSHGEMVSGFGPIY 178
Query: 666 -LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDR 724
I + C + L G C + +W+ S P CE C +++
Sbjct: 179 NYKDTIVFKCQKGFVLRGSSVIHCDADSKWNPSPPACEPNSC----------INLPDIPH 228
Query: 725 SHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLST--CEDNGQWSGTTPTCQY 782
+ T R + DV Y +G +++YRC GYK + +T C+ N +W+ C+
Sbjct: 229 ASWETYPRPT-KEDV---YVVGTVLRYRCHPGYKPTTDEPTTVICQKNLRWT-PYQGCEA 283
Query: 783 VDCGNPGRIENGKVTL-----PSN--ATFYGATAFYQCDENWELEGVIRRMCQENGTWSL 835
+ C P ++ NG++T P+N FYG + C E + CQ +GTWS
Sbjct: 284 LCCPEP-KLNNGEITQHRKSRPANHCVYFYGDEISFSCHETSRFSAI----CQGDGTWSP 338
Query: 836 EPPICKEITCPDPSAQIKAGSGLLVVTSTLSI-GGEAHYQCERGYNLKGHQTRTCISKGQ 894
P C +I C P K G +S+ S E Y+C++GY L G +C S
Sbjct: 339 RTPSCGDI-CNFPP---KIAHGHYKQSSSYSFFKEEIIYECDKGYILVGQAKLSC-SYSH 393
Query: 895 WNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGR 954
W+ P C + CR P + NG++ + + +V C S Y VGP C +
Sbjct: 394 WSAPAPQCKAL-CRKP-ELVNGRLSVDKDQYVEPENVTIQCDSGYGVVGPQSITCSGNRT 451
Query: 955 WSGEEPSCELATNEAVD 971
W E P CE T E +
Sbjct: 452 WYPEVPKCEWETPEGCE 468
Score = 166 bits (404), Expect = 3e-40
Identities = 125/470 (26%), Positives = 193/470 (41%), Gaps = 45/470 (9%)
Query: 452 TCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKA-GSLASYTCENGHILSGSTSVT 510
TC +G W C++ C P + N V + + GS ++C G L GST+
Sbjct: 16 TCNSDGEWVYNT-FCIYKRCRHPGELRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSR 74
Query: 511 CTL---GGAWSGVPPSCKYVNCGTPT-IHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAE 566
C + G WS P C+ V C P I G YG ++C+P + L G
Sbjct: 75 CEVQDRGVGWSHPLPQCEIVKCKPPPDIRNGRHSGEENFYAYGFSVTYSCDPRFSLLGHA 134
Query: 567 ELVCNRD----GKWSYDIPSCELTSCPEPEVPSGGYMEAFD--YYVHSTINFHCEAGHKL 620
+ C + G W P+CE +C +P+V G + F Y TI F C+ G L
Sbjct: 135 SISCTVENETIGVWRPSPPTCEKITCRKPDVSHGEMVSGFGPIYNYKDTIVFKCQKGFVL 194
Query: 621 IGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTH-----LGSVIQYSCT 675
G + C D +W+ P CE C LP +P+ + E T +G+V++Y C
Sbjct: 195 RGSSVIHCDADSKWNPSPPACEPNSCINLPDIPHASWETYPRPTKEDVYVVGTVLRYRCH 254
Query: 676 TNYRLV--GPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRT 733
Y+ P C + +W+ CE + C +P + I H R
Sbjct: 255 PGYKPTTDEPTTVICQKNLRWTPYQ-GCEALCCPEPKLNNGEITQ---------HRKSRP 304
Query: 734 SDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIEN 793
+++ Y G + + C + + C+ +G WS TP+C + C P +I +
Sbjct: 305 ANH----CVYFYGDEISFSCHE----TSRFSAICQGDGTWSPRTPSCGDI-CNFPPKIAH 355
Query: 794 GKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIK 853
G S+ +F+ Y+CD+ + L G + C + WS P CK + C P +
Sbjct: 356 GHYKQSSSYSFFKEEIIYECDKGYILVGQAKLSCSYS-HWSAPAPQCKAL-CRKP----E 409
Query: 854 AGSGLLVVTSTLSIGGE-AHYQCERGYNLKGHQTRTCISKGQWNGTVPVC 902
+G L V + E QC+ GY + G Q+ TC W VP C
Sbjct: 410 LVNGRLSVDKDQYVEPENVTIQCDSGYGVVGPQSITCSGNRTWYPEVPKC 459
Score = 148 bits (358), Expect = 1e-34
Identities = 117/456 (25%), Positives = 189/456 (41%), Gaps = 54/456 (11%)
Query: 353 CGSPDKLLNTTI-LGNDYDVGSRIVYKCPEGHMLLGDKSRHCK---KDGFWSGAPPSCKY 408
C P +L N + + D GS+I + C EG L+G + C+ + WS P C+
Sbjct: 34 CRHPGELRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRGVGWSHPLPQCEI 93
Query: 409 VNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDE----GIWDGEAP 464
V C I +G + +N +G YSC F+L+G+ +C E G+W P
Sbjct: 94 VKCKPPPDIRNGRHSGEENFYAYGFSVTYSCDPRFSLLGHASISCTVENETIGVWRPSPP 153
Query: 465 RCLFDWCPDPPAVSNASVTVNG--HKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPP 522
C C P V+ G + + C+ G +L GS+ + C W+ PP
Sbjct: 154 TCEKITCRKPDVSHGEMVSGFGPIYNYKDTIVFKCQKGFVLRGSSVIHCDADSKWNPSPP 213
Query: 523 SCKYVNC-GTPTIHKGSFVLINGTT-----TYGSIAQFTCEPDYWLNGAE--ELVCNRDG 574
+C+ +C P I S+ T G++ ++ C P Y E ++C ++
Sbjct: 214 ACEPNSCINLPDIPHASWETYPRPTKEDVYVVGTVLRYRCHPGYKPTTDEPTTVICQKNL 273
Query: 575 KWSYDIPSCELTSCPEPEVPSGGYMEAFD--------YYVHSTINFHCEAGHKLIGEPNL 626
+W+ CE CPEP++ +G + Y+ I+F C + +
Sbjct: 274 RWT-PYQGCEALCCPEPKLNNGEITQHRKSRPANHCVYFYGDEISFSCHETSRF----SA 328
Query: 627 VCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRR 686
+CQ DG WS +P+C I C P + +G + + + I Y C Y LVG +
Sbjct: 329 ICQGDGTWSPRTPSCGDI-CNFPPKIAHGHYKQSSSYSFFKEEIIYECDKGYILVGQAKL 387
Query: 687 TCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIG 746
+C+ WS +P+C+ + C P + V G R S ++D Y
Sbjct: 388 SCSYS-HWSAPAPQCKAL-CRKPEL-------VNG----------RLSVDKD---QYVEP 425
Query: 747 ALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQY 782
V +C+ GY V+G TC N W P C++
Sbjct: 426 ENVTIQCDSGYGVVGPQSITCSGNRTWYPEVPKCEW 461
Score = 91.5 bits (217), Expect = 2e-17
Identities = 75/311 (24%), Positives = 119/311 (38%), Gaps = 27/311 (8%)
Query: 352 TCGSPDKLLNTTI--LGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYV 409
TC PD + G Y+ IV+KC +G +L G HC D W+ +PP+C+
Sbjct: 159 TCRKPDVSHGEMVSGFGPIYNYKDTIVFKCQKGFVLRGSSVIHCDADSKWNPSPPACEPN 218
Query: 410 NCGGLTPIEDGDVALIDNRTTH-----GARALYSCRENFTLVGNPERT--CGDEGIWDGE 462
+C L I T G Y C + + T C W
Sbjct: 219 SCINLPDIPHASWETYPRPTKEDVYVVGTVLRYRCHPGYKPTTDEPTTVICQKNLRWT-P 277
Query: 463 APRCLFDWCPDPPAVSNASVTVNGHKA---------GSLASYTCENGHILSGSTSVTCTL 513
C CP+ P ++N +T + G S++C + S C
Sbjct: 278 YQGCEALCCPE-PKLNNGEITQHRKSRPANHCVYFYGDEISFSCHE----TSRFSAICQG 332
Query: 514 GGAWSGVPPSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRD 573
G WS PSC + P I G + + + + + C+ Y L G +L C+
Sbjct: 333 DGTWSPRTPSCGDICNFPPKIAHGHYKQSSSYSFFKEEIIYECDKGYILVGQAKLSCSY- 391
Query: 574 GKWSYDIPSCELTSCPEPEVPSGGYMEAFDYYVH-STINFHCEAGHKLIGEPNLVCQQDG 632
WS P C+ C +PE+ +G D YV + C++G+ ++G ++ C +
Sbjct: 392 SHWSAPAPQCK-ALCRKPELVNGRLSVDKDQYVEPENVTIQCDSGYGVVGPQSITCSGNR 450
Query: 633 EWSGDSPTCEY 643
W + P CE+
Sbjct: 451 TWYPEVPKCEW 461
Score = 34.3 bits (75), Expect = 2.4
Identities = 25/72 (34%), Positives = 29/72 (40%), Gaps = 8/72 (11%)
Query: 1 RCGHPAVPPNARVSIPNEENIVA-GTIAVYECDEGYELFGARQRECTLR----GDWTLEP 55
+C P N R S EEN A G Y CD + L G CT+ G W P
Sbjct: 95 KCKPPPDIRNGRHS--GEENFYAYGFSVTYSCDPRFSLLGHASISCTVENETIGVWRPSP 152
Query: 56 PFCGTNVAFRKP 67
P C + RKP
Sbjct: 153 PTC-EKITCRKP 163
>BC109191-1|AAI09192.1| 526|Homo sapiens CR1L protein protein.
Length = 526
Score = 171 bits (417), Expect = 9e-42
Identities = 137/494 (27%), Positives = 204/494 (41%), Gaps = 55/494 (11%)
Query: 353 CGSPDKL--LNTTILGNDYD--VGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKY 408
C P+ L T L +D++ +G+ + Y+C G+ S C K+ W+ A CK
Sbjct: 35 CNVPEWLPFARPTNLTDDFEFPIGTYLNYECRPGYSGR-PFSIICLKNSVWTSAKDKCKR 93
Query: 409 VNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTC---GDEGIWDGEAPR 465
+C P +A + ++ YSC + + L+G+ TC G+ IWD + P
Sbjct: 94 KSCRN-PPDPVNGMAHVIKDIQFRSQIKYSCPKGYRLIGSSSATCIISGNTVIWDNKTPV 152
Query: 466 CLFDWCPDPPAVSN---ASVTVNGHKAGSLASYTCENG------HILSGSTSVTCTLG-- 514
C C PP ++N S++ GS+ +Y C G L G S+ CT
Sbjct: 153 CDRIICGLPPTIANGDFTSISREYFHYGSVVTYHCNLGSRGKKVFELVGEPSIYCTSKDD 212
Query: 515 --GAWSGVPPSCKYVN-CGTPTIHKGSFVLINGTT-TYGSIAQFTCEPDYWLNGAEELVC 570
G WSG P C N C P + G V N + + + +F C+P + + G + C
Sbjct: 213 QVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFGMKGPSHVKC 272
Query: 571 NRDGKWSYDIPSCELTSCPEPEV--PSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVC 628
KW ++PSC P P+V + ++ + + CE G+ L G L C
Sbjct: 273 QALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGSTYLHC 332
Query: 629 QQDGEWSGDSPTCEYIDCGK-LPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRT 687
G+WS +P CE C L LP G + L LG+ + + C ++L G
Sbjct: 333 TPQGDWSPAAPRCEVKSCDDFLGQLPNGHV-LFPLNLQLGAKVDFVCDEGFQLKGSSASY 391
Query: 688 CT---EEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYR 744
C E W S P CE C P V +V V D+
Sbjct: 392 CVLAGMESLWDSSVPVCERKSCETPPVPVNGMVHVI----------------TDI----H 431
Query: 745 IGALVKYRCEKGYKVIGESLSTCEDNG---QWSGTTPTCQYVDCGNPGRIENGKVT-LPS 800
+G+ + Y C G+++IG S + C +G WS P CQ + C NP I NG+ T P
Sbjct: 432 VGSRINYSCTTGHRLIGHSSAECVLSGNTAHWSMKPPICQQIFCPNPPAILNGRHTGTPL 491
Query: 801 NATFYGATAFYQCD 814
YG Y CD
Sbjct: 492 GDIPYGKEVSYTCD 505
Score = 170 bits (414), Expect = 2e-41
Identities = 123/472 (26%), Positives = 187/472 (39%), Gaps = 51/472 (10%)
Query: 490 GSLASYTCENGHILSGST-SVTCTLGGAWSGVPPSCKYVNCGTPTIHKGSFVLINGTTTY 548
G+ +Y C G+ SG S+ C W+ CK +C P + +
Sbjct: 58 GTYLNYECRPGY--SGRPFSIICLKNSVWTSAKDKCKRKSCRNPPDPVNGMAHVIKDIQF 115
Query: 549 GSIAQFTCEPDYWLNGAEELVCNRDGK---WSYDIPSCELTSCP-EPEVPSGGYMEAFDY 604
S +++C Y L G+ C G W P C+ C P + +G +
Sbjct: 116 RSQIKYSCPKGYRLIGSSSATCIISGNTVIWDNKTPVCDRIICGLPPTIANGDFTSISRE 175
Query: 605 YVH--STINFHCEAGHK------LIGEPNLVC----QQDGEWSGDSPTCEYIDCGKLPTL 652
Y H S + +HC G + L+GEP++ C Q G WSG +P C + P +
Sbjct: 176 YFHYGSVVTYHCNLGSRGKKVFELVGEPSIYCTSKDDQVGIWSGPAPQCIIPNKCTPPNV 235
Query: 653 PYGTMELLNGTTH-LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIV 711
G + N + L V+++ C + + GP C +W P C + C P
Sbjct: 236 ENGILVSDNRSLFSLNEVVEFRCQPGFGMKGPSHVKCQALNKWEPELPSCSRV-CQPP-- 292
Query: 712 AEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNG 771
D H R DN + G V Y CE GY + G + C G
Sbjct: 293 ----------PDVLHAERTQRDKDN------FSPGQEVFYSCEPGYDLRGSTYLHCTPQG 336
Query: 772 QWSGTTPTCQYVDCGN-PGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQEN 830
WS P C+ C + G++ NG V P N GA + CDE ++L+G C
Sbjct: 337 DWSPAAPRCEVKSCDDFLGQLPNGHVLFPLNLQL-GAKVDFVCDEGFQLKGSSASYCVLA 395
Query: 831 GT---WSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTR 887
G W P+C+ +C P + +G++ V + + +G +Y C G+ L GH +
Sbjct: 396 GMESLWDSSVPVCERKSCETPPVPV---NGMVHVITDIHVGSRINYSCTTGHRLIGHSSA 452
Query: 888 TCISKG---QWNGTVPVCIPIDCRSPGNIENGKIV-ISNGSTLFGSSVEYYC 935
C+ G W+ P+C I C +P I NG+ G +G V Y C
Sbjct: 453 ECVLSGNTAHWSMKPPICQQIFCPNPPAILNGRHTGTPLGDIPYGKEVSYTC 504
Score = 155 bits (376), Expect = 8e-37
Identities = 130/483 (26%), Positives = 201/483 (41%), Gaps = 57/483 (11%)
Query: 437 YSCRENFTLVGNP-ERTCGDEGIWDGEAPRCLFDWCPDPP-AVSNASVTVNGHKAGSLAS 494
Y CR ++ G P C +W +C C +PP V+ + + + S
Sbjct: 63 YECRPGYS--GRPFSIICLKNSVWTSAKDKCKRKSCRNPPDPVNGMAHVIKDIQFRSQIK 120
Query: 495 YTCENGHILSGSTSVTCTLGG---AWSGVPPSCKYVNCGTP-TIHKGSFVLINGTTT-YG 549
Y+C G+ L GS+S TC + G W P C + CG P TI G F I+ YG
Sbjct: 121 YSCPKGYRLIGSSSATCIISGNTVIWDNKTPVCDRIICGLPPTIANGDFTSISREYFHYG 180
Query: 550 SIAQFTC------EPDYWLNGAEELVC-NRD---GKWSYDIPSCELTS-CPEPEVPSGGY 598
S+ + C + + L G + C ++D G WS P C + + C P V +G
Sbjct: 181 SVVTYHCNLGSRGKKVFELVGEPSIYCTSKDDQVGIWSGPAPQCIIPNKCTPPNVENGIL 240
Query: 599 MEAFD--YYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGT 656
+ + ++ + F C+ G + G ++ CQ +W + P+C + C P + +
Sbjct: 241 VSDNRSLFSLNEVVEFRCQPGFGMKGPSHVKCQALNKWEPELPSCSRV-CQPPPDVLHAE 299
Query: 657 MELLNGTTHL-GSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKS 715
+ G + YSC Y L G CT + WS ++PRCE C D +
Sbjct: 300 RTQRDKDNFSPGQEVFYSCEPGYDLRGSTYLHCTPQGDWSPAAPRCEVKSCDDFL----- 354
Query: 716 IVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQ--- 772
+GH L + ++GA V + C++G+++ G S S C G
Sbjct: 355 ------GQLPNGHVLFPLN--------LQLGAKVDFVCDEGFQLKGSSASYCVLAGMESL 400
Query: 773 WSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGT 832
W + P C+ C P NG V + ++ G+ Y C L G C +G
Sbjct: 401 WDSSVPVCERKSCETPPVPVNGMVHVITDI-HVGSRINYSCTTGHRLIGHSSAECVLSGN 459
Query: 833 ---WSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQC----ERG--YNLKG 883
WS++PPIC++I CP+P A I G + G E Y C +RG +NL G
Sbjct: 460 TAHWSMKPPICQQIFCPNPPA-ILNGRHTGTPLGDIPYGKEVSYTCDPHPDRGMTFNLIG 518
Query: 884 HQT 886
T
Sbjct: 519 EST 521
Score = 120 bits (288), Expect = 4e-26
Identities = 92/376 (24%), Positives = 147/376 (39%), Gaps = 33/376 (8%)
Query: 602 FDYYVHSTINFHCEAGHKLIGEP-NLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELL 660
F++ + + +N+ C G+ G P +++C ++ W+ C+ C P P M +
Sbjct: 53 FEFPIGTYLNYECRPGYS--GRPFSIICLKNSVWTSAKDKCKRKSCRNPPD-PVNGMAHV 109
Query: 661 NGTTHLGSVIQYSCTTNYRLVGPVRRTCT---EEFQWSDSSPRCEEIRCS-DPIVAEKSI 716
S I+YSC YRL+G TC W + +P C+ I C P +A
Sbjct: 110 IKDIQFRSQIKYSCPKGYRLIGSSSATCIISGNTVIWDNKTPVCDRIICGLPPTIANGDF 169
Query: 717 VSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDN----GQ 772
S++ +G + TY + R +K ++++GE C G
Sbjct: 170 TSISREYFHYGSVV-----------TYHCN--LGSRGKKVFELVGEPSIYCTSKDDQVGI 216
Query: 773 WSGTTPTCQYVDCGNPGRIENGKVTLPSNATF-YGATAFYQCDENWELEGVIRRMCQENG 831
WSG P C + P +ENG + + + F ++C + ++G CQ
Sbjct: 217 WSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFGMKGPSHVKCQALN 276
Query: 832 TWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCIS 891
W E P C + P P + S G E Y CE GY+L+G C
Sbjct: 277 KWEPELPSCSRVCQPPPD--VLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGSTYLHCTP 334
Query: 892 KGQWNGTVPVCIPIDCRS-PGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCL 950
+G W+ P C C G + NG ++ L G+ V++ C +Q G C+
Sbjct: 335 QGDWSPAAPRCEVKSCDDFLGQLPNGHVLFPLNLQL-GAKVDFVCDEGFQLKGSSASYCV 393
Query: 951 DDGR---WSGEEPSCE 963
G W P CE
Sbjct: 394 LAGMESLWDSSVPVCE 409
Score = 95.5 bits (227), Expect = 9e-19
Identities = 79/316 (25%), Positives = 123/316 (38%), Gaps = 42/316 (13%)
Query: 666 LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRS 725
+G+ + Y C Y P C + W+ + +C+ C +P + V
Sbjct: 57 IGTYLNYECRPGYS-GRPFSIICLKNSVWTSAKDKCKRKSCRNPPDPVNGMAHVI----- 110
Query: 726 HGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTCQY 782
+D+ + + +KY C KGY++IG S +TC +G W TP C
Sbjct: 111 -----------KDI----QFRSQIKYSCPKGYRLIGSSSATCIISGNTVIWDNKTPVCDR 155
Query: 783 VDCGNPGRIENGKVTLPSNATF-YGATAFYQCD------ENWELEGVIRRMCQEN----G 831
+ CG P I NG T S F YG+ Y C+ + +EL G C G
Sbjct: 156 IICGLPPTIANGDFTSISREYFHYGSVVTYHCNLGSRGKKVFELVGEPSIYCTSKDDQVG 215
Query: 832 TWSLEPPICKEITCPDPSAQIKAGSGLLVVT--STLSIGGEAHYQCERGYNLKGHQTRTC 889
WS P C P+ +G+LV S S+ ++C+ G+ +KG C
Sbjct: 216 IWSGPAPQC---IIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFGMKGPSHVKC 272
Query: 890 ISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLF-GSSVEYYCLSQYQRVGPFLRK 948
+ +W +P C + C+ P ++ + + + G V Y C Y G
Sbjct: 273 QALNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGSTYLH 331
Query: 949 CLDDGRWSGEEPSCEL 964
C G WS P CE+
Sbjct: 332 CTPQGDWSPAAPRCEV 347
Score = 46.4 bits (105), Expect = 6e-04
Identities = 26/73 (35%), Positives = 35/73 (47%), Gaps = 4/73 (5%)
Query: 352 TCGSPDKLLNTTI-LGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDG---FWSGAPPSCK 407
+C +P +N + + D VGSRI Y C GH L+G S C G WS PP C+
Sbjct: 412 SCETPPVPVNGMVHVITDIHVGSRINYSCTTGHRLIGHSSAECVLSGNTAHWSMKPPICQ 471
Query: 408 YVNCGGLTPIEDG 420
+ C I +G
Sbjct: 472 QIFCPNPPAILNG 484
Score = 41.5 bits (93), Expect = 0.016
Identities = 20/60 (33%), Positives = 30/60 (50%), Gaps = 5/60 (8%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGD---WTLEPPFC 58
C P VP N V + + ++ G+ Y C G+ L G EC L G+ W+++PP C
Sbjct: 413 CETPPVPVNGMVHVITDIHV--GSRINYSCTTGHRLIGHSSAECVLSGNTAHWSMKPPIC 470
Score = 39.9 bits (89), Expect = 0.049
Identities = 18/57 (31%), Positives = 28/57 (49%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C P +A + +++N G Y C+ GY+L G+ CT +GDW+ P C
Sbjct: 289 CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGSTYLHCTPQGDWSPAAPRC 345
>Y00716-1|CAA68704.1| 1231|Homo sapiens factor H protein.
Length = 1231
Score = 169 bits (410), Expect = 6e-41
Identities = 161/618 (26%), Positives = 252/618 (40%), Gaps = 55/618 (8%)
Query: 345 ICQYLPPTCGSPDKLLNTTI---LGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSG 401
IC+ +CG P +LLN + +Y + Y C ++ G C DG W+
Sbjct: 622 ICKEQVQSCGPPPELLNGNVKEKTKEEYGHSEVVEYYCNPRFLMKGPNKIQCV-DGEWTT 680
Query: 402 APPSC-KYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWD 460
P + CG + +E G L +G ++C E+FT++G+ TC G+W
Sbjct: 681 LPVCIVEESTCGDIPELEHGWAQLSSPPYYYGDSVEFNCSESFTMIGHRSITC-IHGVWT 739
Query: 461 GEAPRCLFDWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSV--TCTLGGAWS 518
+ P+C+ SN + K + + G T + G W
Sbjct: 740 -QLPQCVAIDKLKKCKSSNLIILEEHLKNKKEFDHNSNIRYRCRGKEGWIHTVCINGRWD 798
Query: 519 G-VPPSCKYVNCGTPTIHKGSFVLINGTTTY--GSIAQFTCEPDYWLNGAEELVCNRDGK 575
V S + P + + T Y G C+ +Y + EE+ C +DG+
Sbjct: 799 PEVNCSMAQIQLCPPPPQIPNSHNMTTTLNYRDGEKVSVLCQENYLIQEGEEITC-KDGR 857
Query: 576 WSYDIPSC-ELTSCPEPEVPSGGYMEAF----DYYVHST-INFHCEAGHKLIGEPNLVCQ 629
W IP C E C +P G + + + Y H T +++ CE G ++ E C
Sbjct: 858 WQ-SIPLCVEKIPCSQPPQIEHGTINSSRSSQESYAHGTKLSYTCEGGFRISEENETTCY 916
Query: 630 QDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCT 689
G+WS P CE + C P + +G + ++ + G + Y C + + GP C
Sbjct: 917 M-GKWSSP-PQCEGLPCKSPPEISHGVVAHMSDSYQYGEEVTYKCFEGFGIDGPAIAKCL 974
Query: 690 EEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALV 749
E +WS P C + C +S+ + + I + +DV Y+ G V
Sbjct: 975 GE-KWSHP-PSCIKTDC----------LSLPSFENA-----IPMGEKKDV---YKAGEQV 1014
Query: 750 KYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATF-YGAT 808
Y C YK+ G S TC N +W+G PTC+ C NP ++N + + + G
Sbjct: 1015 TYTCATYYKMDGASNVTCI-NSRWTGR-PTCRDTSCVNPPTVQNAYIVSRQMSKYPSGER 1072
Query: 809 AFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCP-DPSAQIKAGSGLLVVTSTLSI 867
YQC +E+ G MC NG W+ EPP CK+ T P I G S +
Sbjct: 1073 VRYQCRSPYEMFGDEEVMCL-NGNWT-EPPQCKDSTGKCGPPPPIDNGDITSFPLSVYAP 1130
Query: 868 GGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVI--SNGST 925
YQC+ Y L+G++ TC GQW+ P C+ S +EN I + +
Sbjct: 1131 ASSVEYQCQNLYQLEGNKRITC-RNGQWS-EPPKCLHPCVISREIMENYNIALRWTAKQK 1188
Query: 926 LF---GSSVEYYCLSQYQ 940
L+ G SVE+ C Y+
Sbjct: 1189 LYSRTGESVEFVCKRGYR 1206
Score = 147 bits (357), Expect = 2e-34
Identities = 168/642 (26%), Positives = 249/642 (38%), Gaps = 73/642 (11%)
Query: 346 CQYLPPTCGSP-DKLLNTTIL--GNDYDVGSRIVYKCPEGHMLLGD-KSRHCKKDGFWSG 401
CQ P CG P D T L GN ++ G + VY C EG+ LLG+ R C DG W+
Sbjct: 80 CQKRP--CGHPGDTPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYRECDTDG-WTN 136
Query: 402 APPSCKYVNCGGLTPIEDGDV---ALIDNRTTHGARAL-YSCRENFTLVGNPERTCGDEG 457
P C+ V C +T E+G + A+ +R H +A+ + C + + G+ E C D+G
Sbjct: 137 DIPICEVVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCSDDG 196
Query: 458 IWDGEAPRCLFDWCPDPPAVSNASVTVN-GHKAGSLASYTCENGHILSGSTSVTCTLGGA 516
W E P+C+ C P ++ + ++ +K Y C G+ S CT G
Sbjct: 197 FWSKEKPKCVEISCKSPDVINGSPISQKIIYKENERFQYKCNMGYEYSERGDAVCTESG- 255
Query: 517 WSGVPPSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYW-LNGAEELVCNRDGK 575
W + PSC+ +C P I G + + G + C ++ C G
Sbjct: 256 WRPL-PSCEEKSCDNPYIPNGDYSPLRIKHRTGDEITYQCRNGFYPATRGNTAKCTSTG- 313
Query: 576 WSYDIPSCELTSCPEPEVPSGG-YME-----AFDYYVHSTINFHCEAGHKLIGE---PNL 626
W P C L C P++ GG Y E F V +++C+ + ++
Sbjct: 314 W-IPAPRCTLKPCDYPDIKHGGLYHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDHI 372
Query: 627 VCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRR 686
C QDG WS P C P L G + G I +C Y L
Sbjct: 373 HCTQDG-WSPAVPCLR--KC-YFPYLENGYNQNHGRKFVQGKSIDVACHPGYALPKAQTT 428
Query: 687 TCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIG 746
E WS +PRC ++ KS + + S TY +
Sbjct: 429 VTCMENGWS-PTPRCIRVK-----TCSKSSIDIENGFISESQ------------YTYALK 470
Query: 747 ALVKYRCEKGYKVI-GESLST--CEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNAT 803
KY+C+ GY GE+ + C +G WS PTC C P N +
Sbjct: 471 EKAKYQCKLGYVTADGETSGSIRCGKDG-WS-AQPTC-IKSCDIP-VFMNARTKNDFTWF 526
Query: 804 FYGATAFYQCDENWE-----LEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGL 858
T Y+C + +E G I +C NG WS + PIC E C P +
Sbjct: 527 KLNDTLDYECHDGYESNTGSTTGSI--VCGYNG-WS-DLPICYERECELPKIDVHLVPDR 582
Query: 859 LVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIP--IDCRSPGNIENG 916
+G + C+ G+ + G + C G + +P+C C P + NG
Sbjct: 583 --KKDQYKVGEVLKFSCKPGFTIVGPNSVQCYHFG-LSPDLPICKEQVQSCGPPPELLNG 639
Query: 917 KIVISNGSTLFGSS--VEYYCLSQYQRVGPFLRKCLDDGRWS 956
V +G S VEYYC ++ GP +C+ DG W+
Sbjct: 640 N-VKEKTKEEYGHSEVVEYYCNPRFLMKGPNKIQCV-DGEWT 679
Score = 144 bits (348), Expect = 2e-33
Identities = 160/620 (25%), Positives = 258/620 (41%), Gaps = 61/620 (9%)
Query: 366 GNDYDVGSRIVYKCPEGHML-LGDKSRHCKKDGFWSGAPPSCKYVNCGGLT-PIEDGDVA 423
G + G I C G+ L + C ++G WS P + C + IE+G ++
Sbjct: 403 GRKFVQGKSIDVACHPGYALPKAQTTVTCMENG-WSPTPRCIRVKTCSKSSIDIENGFIS 461
Query: 424 LIDNRTTHGARALYSCRENF-TLVGNPERT--CGDEGIWDGEAPRCLFDWCPDPPAVSNA 480
+A Y C+ + T G + CG +G W + P C+ C D P NA
Sbjct: 462 ESQYTYALKEKAKYQCKLGYVTADGETSGSIRCGKDG-WSAQ-PTCIKS-C-DIPVFMNA 517
Query: 481 SVT--VNGHKAGSLASYTCENGHILS-GST--SVTCTLGGAWSGVPPSCKYVNCGTPTIH 535
K Y C +G+ + GST S+ C G WS +P C C P I
Sbjct: 518 RTKNDFTWFKLNDTLDYECHDGYESNTGSTTGSIVCGYNG-WSDLP-ICYERECELPKID 575
Query: 536 KGSFVLINGTTTY--GSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSC--ELTSC-PE 590
V Y G + +F+C+P + + G + C G S D+P C ++ SC P
Sbjct: 576 V-HLVPDRKKDQYKVGEVLKFSCKPGFTIVGPNSVQCYHFGL-SPDLPICKEQVQSCGPP 633
Query: 591 PEVPSGGYMEAF-DYYVHS-TINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTC--EYIDC 646
PE+ +G E + Y HS + ++C + G PN + DGEW+ P C E C
Sbjct: 634 PELLNGNVKEKTKEEYGHSEVVEYYCNPRFLMKG-PNKIQCVDGEWT-TLPVCIVEESTC 691
Query: 647 GKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRC 706
G +P L +G +L + + G ++++C+ ++ ++G TC W+ P+C
Sbjct: 692 GDIPELEHGWAQLSSPPYYYGDSVEFNCSESFTMIGHRSITCIHGV-WT-QLPQC----- 744
Query: 707 SDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLST 766
V++ + LI ++ + + ++YRC +G + G +
Sbjct: 745 ----------VAIDKLKKCKSSNLIILEEHLKNKKEFDHNSNIRYRC-RGKE--GWIHTV 791
Query: 767 CEDNGQWSG--TTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIR 824
C NG+W Q C P +I N + G C EN+ ++
Sbjct: 792 C-INGRWDPEVNCSMAQIQLCPPPPQIPNSHNMTTTLNYRDGEKVSVLCQENYLIQEGEE 850
Query: 825 RMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSI--GGEAHYQCERGYNLK 882
C++ G W P ++I C P QI+ G+ +S S G + Y CE G+ +
Sbjct: 851 ITCKD-GRWQSIPLCVEKIPCSQP-PQIEHGTINSSRSSQESYAHGTKLSYTCEGGFRIS 908
Query: 883 GHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRV 942
TC G+W+ + P C + C+SP I +G + + S +G V Y C +
Sbjct: 909 EENETTCY-MGKWS-SPPQCEGLPCKSPPEISHGVVAHMSDSYQYGEEVTYKCFEGFGID 966
Query: 943 GPFLRKCLDDGRWSGEEPSC 962
GP + KCL + +WS PSC
Sbjct: 967 GPAIAKCLGE-KWS-HPPSC 984
Score = 139 bits (336), Expect = 6e-32
Identities = 144/585 (24%), Positives = 226/585 (38%), Gaps = 66/585 (11%)
Query: 345 ICQYLPPTCGSPDKLLN--TTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGA 402
+C TCG +L + + Y G + + C E ++G +S C G W+
Sbjct: 683 VCIVEESTCGDIPELEHGWAQLSSPPYYYGDSVEFNCSESFTMIGHRSITCIH-GVWTQL 741
Query: 403 PPSC---KYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIW 459
P K C I + H + Y CR + T G W
Sbjct: 742 PQCVAIDKLKKCKSSNLIILEEHLKNKKEFDHNSNIRYRCRGKEGWI----HTVCINGRW 797
Query: 460 DGEAPRCL--FDWCPDPPAVSNAS--VTVNGHKAGSLASYTCENGHILSGSTSVTCTLGG 515
D E + CP PP + N+ T ++ G S C+ +++ +TC G
Sbjct: 798 DPEVNCSMAQIQLCPPPPQIPNSHNMTTTLNYRDGEKVSVLCQENYLIQEGEEITCK-DG 856
Query: 516 AWSGVPPSCKYVNCGTPT-IHKGSFVLINGTT---TYGSIAQFTCEPDYWLNGAEELVCN 571
W +P + + C P I G+ + +G+ +TCE + ++ E C
Sbjct: 857 RWQSIPLCVEKIPCSQPPQIEHGTINSSRSSQESYAHGTKLSYTCEGGFRISEENETTCY 916
Query: 572 RDGKWSYDIPSCELTSCPEP-EVPSGGYMEAFDYYVHST-INFHCEAGHKLIGEPNLVCQ 629
GKWS P CE C P E+ G D Y + + + C G + G C
Sbjct: 917 M-GKWSSP-PQCEGLPCKSPPEISHGVVAHMSDSYQYGEEVTYKCFEGFGIDGPAIAKCL 974
Query: 630 QDGEWSGDSPTCEYIDCGKLPTLPYGT-MELLNGTTHLGSVIQYSCTTNYRLVGPVRRTC 688
+ +WS P+C DC LP+ M G + Y+C T Y++ G TC
Sbjct: 975 GE-KWS-HPPSCIKTDCLSLPSFENAIPMGEKKDVYKAGEQVTYTCATYYKMDGASNVTC 1032
Query: 689 TEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGAL 748
+W+ P C + C +P + + + +R + + Y G
Sbjct: 1033 INS-RWT-GRPTCRDTSCVNPPTVQNAYIV-----------------SRQM-SKYPSGER 1072
Query: 749 VKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQ--YVDCGNPGRIENGKVT-LPSNATFY 805
V+Y+C Y++ G+ C NG W+ P C+ CG P I+NG +T P +
Sbjct: 1073 VRYQCRSPYEMFGDEEVMCL-NGNWT-EPPQCKDSTGKCGPPPPIDNGDITSFPLSVYAP 1130
Query: 806 GATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTL 865
++ YQC ++LEG R C+ NG WS EPP C C ++ + L T+
Sbjct: 1131 ASSVEYQCQNLYQLEGNKRITCR-NGQWS-EPPKCLH-PCVISREIMENYNIALRWTAKQ 1187
Query: 866 SI----GGEAHYQCERGYNL--KGHQTRTCISKGQWNGTV--PVC 902
+ G + C+RGY L + H RT W+G + P C
Sbjct: 1188 KLYSRTGESVEFVCKRGYRLSSRSHTLRTTC----WDGKLEYPTC 1228
Score = 138 bits (334), Expect = 1e-31
Identities = 141/551 (25%), Positives = 216/551 (39%), Gaps = 56/551 (10%)
Query: 437 YSCRENFTLVGNPERTCGDEGIWDGEAPRCL--FDWCPDPPAVSNASV---TVNGHKAGS 491
+SC+ FT+VG C G+ + P C C PP + N +V T +
Sbjct: 595 FSCKPGFTIVGPNSVQCYHFGL-SPDLPICKEQVQSCGPPPELLNGNVKEKTKEEYGHSE 653
Query: 492 LASYTCENGHILSGSTSVTCTLGGAWSGVPPSC-KYVNCGT-PTIHKGSFVLINGTTTYG 549
+ Y C ++ G + C + G W+ +P + CG P + G L + YG
Sbjct: 654 VVEYYCNPRFLMKGPNKIQC-VDGEWTTLPVCIVEESTCGDIPELEHGWAQLSSPPYYYG 712
Query: 550 SIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSC----ELTSCPEPE--VPSGGYMEAFD 603
+F C + + G + C G W+ +P C +L C + +
Sbjct: 713 DSVEFNCSESFTMIGHRSITCIH-GVWT-QLPQCVAIDKLKKCKSSNLIILEEHLKNKKE 770
Query: 604 YYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYID---CGKLPTLPYGTMELL 660
+ +S I + C I + VC +G W + C C P +P
Sbjct: 771 FDHNSNIRYRCRGKEGWI---HTVCI-NGRWDPEV-NCSMAQIQLCPPPPQIPNSHNMTT 825
Query: 661 NGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRC-EEIRCSDPIVAEKSIVSV 719
G + C NY + TC ++ +W S P C E+I CS P E
Sbjct: 826 TLNYRDGEKVSVLCQENYLIQEGEEITC-KDGRWQ-SIPLCVEKIPCSQPPQIE------ 877
Query: 720 TGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPT 779
H I +S R +Y G + Y CE G+++ E+ +TC G+WS + P
Sbjct: 878 --------HGTINSS--RSSQESYAHGTKLSYTCEGGFRISEENETTCY-MGKWS-SPPQ 925
Query: 780 CQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPI 839
C+ + C +P I +G V S++ YG Y+C E + ++G C WS PP
Sbjct: 926 CEGLPCKSPPEISHGVVAHMSDSYQYGEEVTYKCFEGFGIDGPAIAKCL-GEKWS-HPPS 983
Query: 840 CKEITCPD-PSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGT 898
C + C PS + G G + Y C Y + G TCI+ +W G
Sbjct: 984 CIKTDCLSLPSFENAIPMG--EKKDVYKAGEQVTYTCATYYKMDGASNVTCIN-SRWTGR 1040
Query: 899 VPVCIPIDCRSPGNIENGKIVISNGSTL-FGSSVEYYCLSQYQRVGPFLRKCLDDGRWSG 957
P C C +P ++N IV S G V Y C S Y+ G CL +G W+
Sbjct: 1041 -PTCRDTSCVNPPTVQNAYIVSRQMSKYPSGERVRYQCRSPYEMFGDEEVMCL-NGNWT- 1097
Query: 958 EEPSCELATNE 968
E P C+ +T +
Sbjct: 1098 EPPQCKDSTGK 1108
Score = 135 bits (326), Expect = 9e-31
Identities = 154/621 (24%), Positives = 251/621 (40%), Gaps = 67/621 (10%)
Query: 367 NDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCK--YVNCGGLTPIEDGDVA- 423
+ Y VG + + C G ++G S C G S P CK +CG + +G+V
Sbjct: 585 DQYKVGEVLKFSCKPGFTIVGPNSVQCYHFGL-SPDLPICKEQVQSCGPPPELLNGNVKE 643
Query: 424 LIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFD--WCPDPPAVSN-- 479
H Y C F + G + C D G W P C+ + C D P + +
Sbjct: 644 KTKEEYGHSEVVEYYCNPRFLMKGPNKIQCVD-GEWT-TLPVCIVEESTCGDIPELEHGW 701
Query: 480 ASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSC---KYVNCGTPTIHK 536
A ++ + G + C + G S+TC + G W+ +P K C + +
Sbjct: 702 AQLSSPPYYYGDSVEFNCSESFTMIGHRSITC-IHGVWTQLPQCVAIDKLKKCKSSNLII 760
Query: 537 GSFVLINGTT-TYGSIAQFTCE-PDYWLNGAEELVCNRDGKWSYDIPSCELTS---CPEP 591
L N + S ++ C + W++ VC +G+W ++ +C + CP P
Sbjct: 761 LEEHLKNKKEFDHNSNIRYRCRGKEGWIH----TVCI-NGRWDPEV-NCSMAQIQLCPPP 814
Query: 592 -EVPSGGYMEA-FDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKL 649
++P+ M +Y ++ C+ + LI E + +DG W E I C +
Sbjct: 815 PQIPNSHNMTTTLNYRDGEKVSVLCQENY-LIQEGEEITCKDGRWQSIPLCVEKIPCSQP 873
Query: 650 PTLPYGTMELLNGTTHL---GSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRC 706
P + +GT+ + G+ + Y+C +R+ TC +WS S P+CE + C
Sbjct: 874 PQIEHGTINSSRSSQESYAHGTKLSYTCEGGFRISEENETTCYMG-KWS-SPPQCEGLPC 931
Query: 707 SDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLST 766
P + SHG + SD+ Y+ G V Y+C +G+ + G +++
Sbjct: 932 KSP------------PEISHG-VVAHMSDS------YQYGEEVTYKCFEGFGIDGPAIAK 972
Query: 767 CEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFY--GATAFYQCDENWELEGVIR 824
C +WS P+C DC + EN + + Y G Y C ++++G
Sbjct: 973 CLGE-KWSHP-PSCIKTDCLSLPSFENA-IPMGEKKDVYKAGEQVTYTCATYYKMDGASN 1029
Query: 825 RMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGH 884
C N W+ P C++ +C +P ++ + S G YQC Y + G
Sbjct: 1030 VTCI-NSRWTGRPT-CRDTSCVNPPT-VQNAYIVSRQMSKYPSGERVRYQCRSPYEMFGD 1086
Query: 885 QTRTCISKGQWNGTVPVCIPID--CRSPGNIENGKIVISNGSTLF-GSSVEYYCLSQYQR 941
+ C++ G W P C C P I+NG I S SSVEY C + YQ
Sbjct: 1087 EEVMCLN-GNWTEP-PQCKDSTGKCGPPPPIDNGDITSFPLSVYAPASSVEYQCQNLYQL 1144
Query: 942 VGPFLRKCLDDGRWSGEEPSC 962
G C +G+WS E P C
Sbjct: 1145 EGNKRITC-RNGQWS-EPPKC 1163
Score = 129 bits (311), Expect = 6e-29
Identities = 159/650 (24%), Positives = 244/650 (37%), Gaps = 78/650 (12%)
Query: 346 CQYLPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPP- 404
C LPP + ++L + Y G++ +YKC G+ LG+ C+K G W P
Sbjct: 21 CNELPPRRNT--EILTGSWSDQTYPEGTQAIYKCRPGYRSLGNVIMVCRK-GEWVALNPL 77
Query: 405 -SCKYVNCG--GLTPIEDGDVALI-DNRTTHGARALYSCRENFTLVGNPE-RTCGDEGIW 459
C+ CG G TP G L N +G +A+Y+C E + L+G R C +G W
Sbjct: 78 RKCQKRPCGHPGDTPF--GTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYRECDTDG-W 134
Query: 460 DGEAPRCLFDWCPDPPAVSNASVTVNG------HKAGSLASYTCENGHILSGSTSVTCTL 513
+ P C C A N + + + G + C +G+ + G + C+
Sbjct: 135 TNDIPICEVVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCSD 194
Query: 514 GGAWSGVPPSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRD 573
G WS P C ++C +P + GS + Q+ C Y + + VC
Sbjct: 195 DGFWSKEKPKCVEISCKSPDVINGSPISQKIIYKENERFQYKCNMGYEYSERGDAVCTES 254
Query: 574 GKWSYDIPSCELTSCPEPEVPSGGYME-AFDYYVHSTINFHCEAGHKLIGEPNLV-CQQD 631
G W +PSCE SC P +P+G Y + I + C G N C
Sbjct: 255 G-WR-PLPSCEEKSCDNPYIPNGDYSPLRIKHRTGDEITYQCRNGFYPATRGNTAKCTST 312
Query: 632 GEWSGDSPTCEYIDCGKLPTLPYG-----TMELLNGTTHLGSVIQYSCTTNYRLVGPV-- 684
G W +P C C P + +G M +G Y C ++
Sbjct: 313 G-WI-PAPRCTLKPC-DYPDIKHGGLYHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYW 369
Query: 685 -RRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTY 743
CT++ WS + P C +C P + G +++HG ++
Sbjct: 370 DHIHCTQD-GWSPAVP-CLR-KCYFPYLE-------NGYNQNHGRKFVQ----------- 408
Query: 744 RIGALVKYRCEKGYKV-IGESLSTCEDNGQWSGTTPTCQYVDCGNPG-RIENGKVTLPSN 801
G + C GY + ++ TC +NG WS T + C IENG ++
Sbjct: 409 --GKSIDVACHPGYALPKAQTTVTCMENG-WSPTPRCIRVKTCSKSSIDIENGFISESQY 465
Query: 802 ATFYGATAFYQCDENW-----ELEGVIRRMCQENGTWSLEPPICKEITCP-DPSAQIKAG 855
A YQC + E G IR C ++G WS +P K P +A+ K
Sbjct: 466 TYALKEKAKYQCKLGYVTADGETSGSIR--CGKDG-WSAQPTCIKSCDIPVFMNARTKND 522
Query: 856 SGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNG--TVPVCIPIDCRSPGNI 913
+ TL Y+C GY T I G +NG +P+C +C P
Sbjct: 523 FTWFKLNDTLD------YECHDGYESNTGSTTGSIVCG-YNGWSDLPICYERECELPKID 575
Query: 914 ENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
+ G +++ C + VGP +C G S + P C+
Sbjct: 576 VHLVPDRKKDQYKVGEVLKFSCKPGFTIVGPNSVQCYHFG-LSPDLPICK 624
Score = 120 bits (290), Expect = 2e-26
Identities = 117/468 (25%), Positives = 193/468 (41%), Gaps = 55/468 (11%)
Query: 332 WN-DVGCNLDYLHWICQYLPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKS 390
W+ +V C++ + Q PP P+ TT L +Y G ++ C E +++ +
Sbjct: 797 WDPEVNCSMAQI----QLCPPPPQIPNSHNMTTTL--NYRDGEKVSVLCQENYLIQEGEE 850
Query: 391 RHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDV---ALIDNRTTHGARALYSCRENFTLVG 447
CK DG W P + + C IE G + HG + Y+C F +
Sbjct: 851 ITCK-DGRWQSIPLCVEKIPCSQPPQIEHGTINSSRSSQESYAHGTKLSYTCEGGFRISE 909
Query: 448 NPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVT--VNGHKAGSLASYTCENGHILSG 505
E TC G W P+C C PP +S+ V + ++ G +Y C G + G
Sbjct: 910 ENETTCY-MGKWSSP-PQCEGLPCKSPPEISHGVVAHMSDSYQYGEEVTYKCFEGFGIDG 967
Query: 506 STSVTCTLGGAWSGVPPSCKYVNCGTPTIHKGSFVLINGTTTY--GSIAQFTCEPDYWLN 563
C LG WS PPSC +C + + + + Y G +TC Y ++
Sbjct: 968 PAIAKC-LGEKWSH-PPSCIKTDCLSLPSFENAIPMGEKKDVYKAGEQVTYTCATYYKMD 1025
Query: 564 GAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYM---EAFDYYVHSTINFHCEAGHKL 620
GA + C + +W+ P+C TSC P Y+ + Y + + C + +++
Sbjct: 1026 GASNVTCI-NSRWT-GRPTCRDTSCVNPPTVQNAYIVSRQMSKYPSGERVRYQCRSPYEM 1083
Query: 621 IGEPNLVCQQDGEWSGDSPTCEYID--CGKLPTLPYGTMELLNGTTHL-GSVIQYSCTTN 677
G+ ++C +G W+ + P C+ CG P + G + + + S ++Y C
Sbjct: 1084 FGDEEVMCL-NGNWT-EPPQCKDSTGKCGPPPPIDNGDITSFPLSVYAPASSVEYQCQNL 1141
Query: 678 YRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNR 737
Y+L G R TC QWS E +C P V + I+ ++ L T+ +
Sbjct: 1142 YQLEGNKRITC-RNGQWS------EPPKCLHPCVISREIM------ENYNIALRWTAKQK 1188
Query: 738 DVGNTYRIGALVKYRCEKGYKVIGES---LSTCEDNGQWSGTT--PTC 780
T G V++ C++GY++ S +TC W G PTC
Sbjct: 1189 LYSRT---GESVEFVCKRGYRLSSRSHTLRTTC-----WDGKLEYPTC 1228
Score = 117 bits (282), Expect = 2e-25
Identities = 131/520 (25%), Positives = 193/520 (37%), Gaps = 51/520 (9%)
Query: 406 CKYVNCGGLTPIEDGDV---ALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGE 462
C +C L P + ++ + D G +A+Y CR + +GN C +G W
Sbjct: 16 CVAEDCNELPPRRNTEILTGSWSDQTYPEGTQAIYKCRPGYRSLGNVIMVCR-KGEWVAL 74
Query: 463 AP--RCLFDWCPDPPAVSNASVTVNGHKA---GSLASYTCENGHILSGSTSVT-CTLGGA 516
P +C C P + T+ G G A YTC G+ L G + C G
Sbjct: 75 NPLRKCQKRPCGHPGDTPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYRECDTDG- 133
Query: 517 WSGVPPSCKYVNCGTPTIHKGSFVLINGTTT-----YGSIAQFTCEPDYWLNGAEELVCN 571
W+ P C+ V C T + ++ + +G +F C Y + G EE+ C+
Sbjct: 134 WTNDIPICEVVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCS 193
Query: 572 RDGKWSYDIPSCELTSCPEPEVPSGG-YMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQ 630
DG WS + P C SC P+V +G + Y + + C G++ + VC +
Sbjct: 194 DDGFWSKEKPKCVEISCKSPDVINGSPISQKIIYKENERFQYKCNMGYEYSERGDAVCTE 253
Query: 631 DGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTN-YRLVGPVRRTCT 689
G W P+CE C P +P G L G I Y C Y CT
Sbjct: 254 SG-WR-PLPSCEEKSCDN-PYIPNGDYSPLRIKHRTGDEITYQCRNGFYPATRGNTAKCT 310
Query: 690 EEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALV 749
W +PRC C P D HG + + R +G
Sbjct: 311 ST-GWI-PAPRCTLKPCDYP-------------DIKHGG--LYHENMRRPYFPVAVGKYY 353
Query: 750 KYRCEKGYKVIGESL---STCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYG 806
Y C++ ++ S C +G WS P + C P +ENG G
Sbjct: 354 SYYCDEHFETPSGSYWDHIHCTQDG-WSPAVPCLR--KCYFP-YLENGYNQNHGRKFVQG 409
Query: 807 ATAFYQCDENWEL-EGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTL 865
+ C + L + C ENG WS P + TC S I+ G + T
Sbjct: 410 KSIDVACHPGYALPKAQTTVTCMENG-WSPTPRCIRVKTCSKSSIDIENGF-ISESQYTY 467
Query: 866 SIGGEAHYQCERGYNLKGHQTRTCISKGQ--WNGTVPVCI 903
++ +A YQC+ GY +T I G+ W+ P CI
Sbjct: 468 ALKEKAKYQCKLGYVTADGETSGSIRCGKDGWSAQ-PTCI 506
Score = 115 bits (277), Expect = 8e-25
Identities = 151/641 (23%), Positives = 251/641 (39%), Gaps = 62/641 (9%)
Query: 345 ICQYLPPTCGSPDKLLNTTILGN-DYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAP 403
+ + LP T K++++ + + +Y G + + C G+ + GD+ HC DGFWS
Sbjct: 143 VVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCSDDGFWSKEK 202
Query: 404 PSCKYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEA 463
P C ++C I ++ R Y C + + C + G W
Sbjct: 203 PKCVEISCKSPDVINGSPISQ-KIIYKENERFQYKCNMGYEYSERGDAVCTESG-W-RPL 259
Query: 464 PRCLFDWCPDPPAVSNA--SVTVNGHKAGSLASYTCENG-HILSGSTSVTCTLGGAWSGV 520
P C C D P + N S H+ G +Y C NG + + + CT G W +
Sbjct: 260 PSCEEKSC-DNPYIPNGDYSPLRIKHRTGDEITYQCRNGFYPATRGNTAKCTSTG-W--I 315
Query: 521 P-PSCKYVNCGTPTIHKGSFVLINGTTTY-----GSIAQFTCEPDYWL-NGA--EELVCN 571
P P C C P I G N Y G + C+ + +G+ + + C
Sbjct: 316 PAPRCTLKPCDYPDIKHGGLYHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDHIHCT 375
Query: 572 RDGKWSYDIPSCELTSCPEPEVPSGGYMEAFDYYVH-STINFHCEAGHKL-IGEPNLVCQ 629
+DG WS +P C L C P + +G +V +I+ C G+ L + + C
Sbjct: 376 QDG-WSPAVP-C-LRKCYFPYLENGYNQNHGRKFVQGKSIDVACHPGYALPKAQTTVTCM 432
Query: 630 QDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCT 689
++G W SPT C ++ T ++++ NG S QY+ Y L + C
Sbjct: 433 ENG-W---SPTPR---CIRVKTCSKSSIDIENGFI---SESQYT----YALKEKAKYQCK 478
Query: 690 EEFQWSDSSPRCEEIRC-SDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGAL 748
+ +D IRC D A+ + + +S + + ++ +++
Sbjct: 479 LGYVTADGE-TSGSIRCGKDGWSAQPTCI------KSCDIPVFMNARTKNDFTWFKLNDT 531
Query: 749 VKYRCEKGYKVIGESLS---TCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATF- 804
+ Y C GY+ S + C NG WS P C +C P +I+ V +
Sbjct: 532 LDYECHDGYESNTGSTTGSIVCGYNG-WS-DLPICYERECELP-KIDVHLVPDRKKDQYK 588
Query: 805 YGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKE-ITCPDPSAQIKAGSGLLVVTS 863
G + C + + G C G S + PICKE + P ++ G+
Sbjct: 589 VGEVLKFSCKPGFTIVGPNSVQCYHFGL-SPDLPICKEQVQSCGPPPELLNGNVKEKTKE 647
Query: 864 TLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPID--CRSPGNIENGKIVIS 921
Y C + +KG C+ G+W T+PVCI + C +E+G +S
Sbjct: 648 EYGHSEVVEYYCNPRFLMKGPNKIQCVD-GEWT-TLPVCIVEESTCGDIPELEHGWAQLS 705
Query: 922 NGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
+ +G SVE+ C + +G C+ G W+ + P C
Sbjct: 706 SPPYYYGDSVEFNCSESFTMIGHRSITCI-HGVWT-QLPQC 744
Score = 109 bits (263), Expect = 4e-23
Identities = 158/643 (24%), Positives = 245/643 (38%), Gaps = 74/643 (11%)
Query: 352 TCGSPDKLLNTTILGND-YDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVN 410
+C SPD + + I Y R YKC G+ C + G W P SC+ +
Sbjct: 209 SCKSPDVINGSPISQKIIYKENERFQYKCNMGYEYSERGDAVCTESG-WRPLP-SCEEKS 266
Query: 411 CGGLTPIEDGDVALIDNRTTHGARALYSCRENF--TLVGNPERTCGDEGIWDGEAPRCLF 468
C I +GD + + + G Y CR F GN + C G W APRC
Sbjct: 267 CDN-PYIPNGDYSPLRIKHRTGDEITYQCRNGFYPATRGNTAK-CTSTG-WI-PAPRCTL 322
Query: 469 DWCPDPPAVSNASVTVNGHK------AGSLASYTC-ENGHILSGS--TSVTCTLGGAWSG 519
C P N + G SY C E+ SGS + CT G WS
Sbjct: 323 KPCDYPDIKHGGLYHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDHIHCTQDG-WSP 381
Query: 520 VPPSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYD 579
P + C P + G G C P Y L A+ V + WS
Sbjct: 382 AVPCLR--KCYFPYLENGYNQNHGRKFVQGKSIDVACHPGYALPKAQTTVTCMENGWS-P 438
Query: 580 IPSC-ELTSCPEP--EVPSGGYMEA-FDYYVHSTINFHCEAGHKLI-GEPN--LVCQQDG 632
P C + +C + ++ +G E+ + Y + + C+ G+ GE + + C +DG
Sbjct: 439 TPRCIRVKTCSKSSIDIENGFISESQYTYALKEKAKYQCKLGYVTADGETSGSIRCGKDG 498
Query: 633 EWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRL-VGPVRRTCTEE 691
WS PTC I +P + L + Y C Y G +
Sbjct: 499 -WSAQ-PTC--IKSCDIPVFMNARTKNDFTWFKLNDTLDYECHDGYESNTGSTTGSIVCG 554
Query: 692 FQ-WSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVK 750
+ WSD P C E C P + + +V D+ Y++G ++K
Sbjct: 555 YNGWSDL-PICYERECELPKI-DVHLVPDRKKDQ------------------YKVGEVLK 594
Query: 751 YRCEKGYKVIGESLSTCEDNGQWSGTTPTC--QYVDCGNPGRIENGKVTLPSNATF-YGA 807
+ C+ G+ ++G + C G S P C Q CG P + NG V + + +
Sbjct: 595 FSCKPGFTIVGPNSVQCYHFG-LSPDLPICKEQVQSCGPPPELLNGNVKEKTKEEYGHSE 653
Query: 808 TAFYQCDENWELEGVIRRMCQENGTWSLEPP-ICKEITCPDPSAQIKAGSGLLVVTSTLS 866
Y C+ + ++G + C + G W+ P I +E TC D +++ G L +
Sbjct: 654 VVEYYCNPRFLMKGPNKIQCVD-GEWTTLPVCIVEESTCGD-IPELEHGWAQL-SSPPYY 710
Query: 867 IGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPID----CRSPGNIENGKIVISN 922
G + C + + GH++ TCI G W +P C+ ID C+S I + + +
Sbjct: 711 YGDSVEFNCSESFTMIGHRSITCI-HGVWT-QLPQCVAIDKLKKCKSSNLIILEEHLKNK 768
Query: 923 GSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCELA 965
S++ Y C + G C+ +GRW E +C +A
Sbjct: 769 KEFDHNSNIRYRCRG---KEGWIHTVCI-NGRWD-PEVNCSMA 806
Score = 94.3 bits (224), Expect = 2e-18
Identities = 86/337 (25%), Positives = 126/337 (37%), Gaps = 43/337 (12%)
Query: 641 CEYIDCGKLPTLPYGTMELLNG-----TTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWS 695
C DC +LP P E+L G T G+ Y C YR +G V C + +W
Sbjct: 16 CVAEDCNELP--PRRNTEILTGSWSDQTYPEGTQAIYKCRPGYRSLGNVIMVCRKG-EWV 72
Query: 696 DSSP--RCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRC 753
+P +C++ C P ++TG GN + G Y C
Sbjct: 73 ALNPLRKCQKRPCGHPGDTPFGTFTLTG------------------GNVFEYGVKAVYTC 114
Query: 754 EKGYKVIGE-SLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTL----PSNATFYGAT 808
+GY+++GE + C+ +G W+ P C+ V C ENGK+ P +G
Sbjct: 115 NEGYQLLGEINYRECDTDG-WTNDIPICEVVKCLPVTAPENGKIVSSAMEPDREYHFGQA 173
Query: 809 AFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIG 868
+ C+ +++EG C ++G WS E P C EI+C P + ++
Sbjct: 174 VRFVCNSGYKIEGDEEMHCSDDGFWSKEKPKCVEISCKSPDVINGSPISQKIIYKE---N 230
Query: 869 GEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFG 928
Y+C GY C G W +P C C +P I NG G
Sbjct: 231 ERFQYKCNMGYEYSERGDAVCTESG-WR-PLPSCEEKSCDNP-YIPNGDYSPLRIKHRTG 287
Query: 929 SSVEYYCLSQ-YQRVGPFLRKCLDDGRWSGEEPSCEL 964
+ Y C + Y KC G W P C L
Sbjct: 288 DEITYQCRNGFYPATRGNTAKCTSTG-WI-PAPRCTL 322
Score = 45.6 bits (103), Expect = 0.001
Identities = 23/58 (39%), Positives = 28/58 (48%), Gaps = 2/58 (3%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFG-ARQRECTLRGDWTLEPPFC 58
CGHP P ++ G AVY C+EGY+L G REC G WT + P C
Sbjct: 85 CGHPGDTPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYRECDTDG-WTNDIPIC 141
Score = 37.9 bits (84), Expect = 0.20
Identities = 20/57 (35%), Positives = 27/57 (47%), Gaps = 2/57 (3%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C +P NA + +G Y+C YE+FG + C L G+WT EPP C
Sbjct: 1048 CVNPPTVQNAYIVSRQMSKYPSGERVRYQCRSPYEMFGDEEVMC-LNGNWT-EPPQC 1102
>M17517-1|AAA52016.1| 657|Homo sapiens HF protein.
Length = 657
Score = 169 bits (410), Expect = 6e-41
Identities = 161/618 (26%), Positives = 252/618 (40%), Gaps = 55/618 (8%)
Query: 345 ICQYLPPTCGSPDKLLNTTI---LGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSG 401
IC+ +CG P +LLN + +Y + Y C ++ G C DG W+
Sbjct: 48 ICKEQVQSCGPPPELLNGNVKEKTKEEYGHSEVVEYYCNPRFLMKGPNKIQCV-DGEWTT 106
Query: 402 APPSC-KYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWD 460
P + CG + +E G L +G ++C E+FT++G+ TC G+W
Sbjct: 107 LPVCIVEESTCGDIPELEHGWAQLSSPPYYYGDSVEFNCSESFTMIGHRSITC-IHGVWT 165
Query: 461 GEAPRCLFDWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSV--TCTLGGAWS 518
+ P+C+ SN + K + + G T + G W
Sbjct: 166 -QLPQCVAIDKLKKCKSSNLIILEEHLKNKKEFDHNSNIRYRCRGKEGWIHTVCINGRWD 224
Query: 519 G-VPPSCKYVNCGTPTIHKGSFVLINGTTTY--GSIAQFTCEPDYWLNGAEELVCNRDGK 575
V S + P + + T Y G C+ +Y + EE+ C +DG+
Sbjct: 225 PEVNCSMAQIQLCPPPPQIPNSHNMTTTLNYRDGEKVSVLCQENYLIQEGEEITC-KDGR 283
Query: 576 WSYDIPSC-ELTSCPEPEVPSGGYMEAF----DYYVHST-INFHCEAGHKLIGEPNLVCQ 629
W IP C E C +P G + + + Y H T +++ CE G ++ E C
Sbjct: 284 WQ-SIPLCVEKIPCSQPPQIEHGTINSSRSSQESYAHGTKLSYTCEGGFRISEENETTCY 342
Query: 630 QDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCT 689
G+WS P CE + C P + +G + ++ + G + Y C + + GP C
Sbjct: 343 M-GKWSSP-PQCEGLPCKSPPEISHGVVAHMSDSYQYGEEVTYKCFEGFGIDGPAIAKCL 400
Query: 690 EEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALV 749
E +WS P C + C +S+ + + I + +DV Y+ G V
Sbjct: 401 GE-KWSHP-PSCIKTDC----------LSLPSFENA-----IPMGEKKDV---YKAGEQV 440
Query: 750 KYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATF-YGAT 808
Y C YK+ G S TC N +W+G PTC+ C NP ++N + + + G
Sbjct: 441 TYTCATYYKMDGASNVTCI-NSRWTGR-PTCRDTSCVNPPTVQNAYIVSRQMSKYPSGER 498
Query: 809 AFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCP-DPSAQIKAGSGLLVVTSTLSI 867
YQC +E+ G MC NG W+ EPP CK+ T P I G S +
Sbjct: 499 VRYQCRSPYEMFGDEEVMCL-NGNWT-EPPQCKDSTGKCGPPPPIDNGDITSFPLSVYAP 556
Query: 868 GGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVI--SNGST 925
YQC+ Y L+G++ TC GQW+ P C+ S +EN I + +
Sbjct: 557 ASSVEYQCQNLYQLEGNKRITC-RNGQWS-EPPKCLHPCVISREIMENYNIALRWTAKQK 614
Query: 926 LF---GSSVEYYCLSQYQ 940
L+ G SVE+ C Y+
Sbjct: 615 LYSRTGESVEFVCKRGYR 632
Score = 139 bits (336), Expect = 6e-32
Identities = 144/585 (24%), Positives = 226/585 (38%), Gaps = 66/585 (11%)
Query: 345 ICQYLPPTCGSPDKLLN--TTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGA 402
+C TCG +L + + Y G + + C E ++G +S C G W+
Sbjct: 109 VCIVEESTCGDIPELEHGWAQLSSPPYYYGDSVEFNCSESFTMIGHRSITCIH-GVWTQL 167
Query: 403 PPSC---KYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIW 459
P K C I + H + Y CR + T G W
Sbjct: 168 PQCVAIDKLKKCKSSNLIILEEHLKNKKEFDHNSNIRYRCRGKEGWI----HTVCINGRW 223
Query: 460 DGEAPRCL--FDWCPDPPAVSNAS--VTVNGHKAGSLASYTCENGHILSGSTSVTCTLGG 515
D E + CP PP + N+ T ++ G S C+ +++ +TC G
Sbjct: 224 DPEVNCSMAQIQLCPPPPQIPNSHNMTTTLNYRDGEKVSVLCQENYLIQEGEEITCK-DG 282
Query: 516 AWSGVPPSCKYVNCGTPT-IHKGSFVLINGTT---TYGSIAQFTCEPDYWLNGAEELVCN 571
W +P + + C P I G+ + +G+ +TCE + ++ E C
Sbjct: 283 RWQSIPLCVEKIPCSQPPQIEHGTINSSRSSQESYAHGTKLSYTCEGGFRISEENETTCY 342
Query: 572 RDGKWSYDIPSCELTSCPEP-EVPSGGYMEAFDYYVHST-INFHCEAGHKLIGEPNLVCQ 629
GKWS P CE C P E+ G D Y + + + C G + G C
Sbjct: 343 M-GKWSSP-PQCEGLPCKSPPEISHGVVAHMSDSYQYGEEVTYKCFEGFGIDGPAIAKCL 400
Query: 630 QDGEWSGDSPTCEYIDCGKLPTLPYGT-MELLNGTTHLGSVIQYSCTTNYRLVGPVRRTC 688
+ +WS P+C DC LP+ M G + Y+C T Y++ G TC
Sbjct: 401 GE-KWS-HPPSCIKTDCLSLPSFENAIPMGEKKDVYKAGEQVTYTCATYYKMDGASNVTC 458
Query: 689 TEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGAL 748
+W+ P C + C +P + + + +R + + Y G
Sbjct: 459 INS-RWT-GRPTCRDTSCVNPPTVQNAYIV-----------------SRQM-SKYPSGER 498
Query: 749 VKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQ--YVDCGNPGRIENGKVT-LPSNATFY 805
V+Y+C Y++ G+ C NG W+ P C+ CG P I+NG +T P +
Sbjct: 499 VRYQCRSPYEMFGDEEVMCL-NGNWT-EPPQCKDSTGKCGPPPPIDNGDITSFPLSVYAP 556
Query: 806 GATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTL 865
++ YQC ++LEG R C+ NG WS EPP C C ++ + L T+
Sbjct: 557 ASSVEYQCQNLYQLEGNKRITCR-NGQWS-EPPKCLH-PCVISREIMENYNIALRWTAKQ 613
Query: 866 SI----GGEAHYQCERGYNL--KGHQTRTCISKGQWNGTV--PVC 902
+ G + C+RGY L + H RT W+G + P C
Sbjct: 614 KLYSRTGESVEFVCKRGYRLSSRSHTLRTTC----WDGKLEYPTC 654
Score = 138 bits (334), Expect = 1e-31
Identities = 141/551 (25%), Positives = 216/551 (39%), Gaps = 56/551 (10%)
Query: 437 YSCRENFTLVGNPERTCGDEGIWDGEAPRCL--FDWCPDPPAVSNASV---TVNGHKAGS 491
+SC+ FT+VG C G+ + P C C PP + N +V T +
Sbjct: 21 FSCKPGFTIVGPNSVQCYHFGL-SPDLPICKEQVQSCGPPPELLNGNVKEKTKEEYGHSE 79
Query: 492 LASYTCENGHILSGSTSVTCTLGGAWSGVPPSC-KYVNCGT-PTIHKGSFVLINGTTTYG 549
+ Y C ++ G + C + G W+ +P + CG P + G L + YG
Sbjct: 80 VVEYYCNPRFLMKGPNKIQC-VDGEWTTLPVCIVEESTCGDIPELEHGWAQLSSPPYYYG 138
Query: 550 SIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSC----ELTSCPEPE--VPSGGYMEAFD 603
+F C + + G + C G W+ +P C +L C + +
Sbjct: 139 DSVEFNCSESFTMIGHRSITCIH-GVWT-QLPQCVAIDKLKKCKSSNLIILEEHLKNKKE 196
Query: 604 YYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYID---CGKLPTLPYGTMELL 660
+ +S I + C I + VC +G W + C C P +P
Sbjct: 197 FDHNSNIRYRCRGKEGWI---HTVCI-NGRWDPEV-NCSMAQIQLCPPPPQIPNSHNMTT 251
Query: 661 NGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRC-EEIRCSDPIVAEKSIVSV 719
G + C NY + TC ++ +W S P C E+I CS P E
Sbjct: 252 TLNYRDGEKVSVLCQENYLIQEGEEITC-KDGRWQ-SIPLCVEKIPCSQPPQIE------ 303
Query: 720 TGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPT 779
H I +S R +Y G + Y CE G+++ E+ +TC G+WS + P
Sbjct: 304 --------HGTINSS--RSSQESYAHGTKLSYTCEGGFRISEENETTCY-MGKWS-SPPQ 351
Query: 780 CQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPI 839
C+ + C +P I +G V S++ YG Y+C E + ++G C WS PP
Sbjct: 352 CEGLPCKSPPEISHGVVAHMSDSYQYGEEVTYKCFEGFGIDGPAIAKCL-GEKWS-HPPS 409
Query: 840 CKEITCPD-PSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGT 898
C + C PS + G G + Y C Y + G TCI+ +W G
Sbjct: 410 CIKTDCLSLPSFENAIPMG--EKKDVYKAGEQVTYTCATYYKMDGASNVTCIN-SRWTGR 466
Query: 899 VPVCIPIDCRSPGNIENGKIVISNGSTL-FGSSVEYYCLSQYQRVGPFLRKCLDDGRWSG 957
P C C +P ++N IV S G V Y C S Y+ G CL +G W+
Sbjct: 467 -PTCRDTSCVNPPTVQNAYIVSRQMSKYPSGERVRYQCRSPYEMFGDEEVMCL-NGNWT- 523
Query: 958 EEPSCELATNE 968
E P C+ +T +
Sbjct: 524 EPPQCKDSTGK 534
Score = 135 bits (326), Expect = 9e-31
Identities = 154/621 (24%), Positives = 251/621 (40%), Gaps = 67/621 (10%)
Query: 367 NDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCK--YVNCGGLTPIEDGDVA- 423
+ Y VG + + C G ++G S C G S P CK +CG + +G+V
Sbjct: 11 DQYKVGEVLKFSCKPGFTIVGPNSVQCYHFGL-SPDLPICKEQVQSCGPPPELLNGNVKE 69
Query: 424 LIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFD--WCPDPPAVSN-- 479
H Y C F + G + C D G W P C+ + C D P + +
Sbjct: 70 KTKEEYGHSEVVEYYCNPRFLMKGPNKIQCVD-GEWT-TLPVCIVEESTCGDIPELEHGW 127
Query: 480 ASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSC---KYVNCGTPTIHK 536
A ++ + G + C + G S+TC + G W+ +P K C + +
Sbjct: 128 AQLSSPPYYYGDSVEFNCSESFTMIGHRSITC-IHGVWTQLPQCVAIDKLKKCKSSNLII 186
Query: 537 GSFVLINGTT-TYGSIAQFTCE-PDYWLNGAEELVCNRDGKWSYDIPSCELTS---CPEP 591
L N + S ++ C + W++ VC +G+W ++ +C + CP P
Sbjct: 187 LEEHLKNKKEFDHNSNIRYRCRGKEGWIH----TVCI-NGRWDPEV-NCSMAQIQLCPPP 240
Query: 592 -EVPSGGYMEA-FDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKL 649
++P+ M +Y ++ C+ + LI E + +DG W E I C +
Sbjct: 241 PQIPNSHNMTTTLNYRDGEKVSVLCQENY-LIQEGEEITCKDGRWQSIPLCVEKIPCSQP 299
Query: 650 PTLPYGTMELLNGTTHL---GSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRC 706
P + +GT+ + G+ + Y+C +R+ TC +WS S P+CE + C
Sbjct: 300 PQIEHGTINSSRSSQESYAHGTKLSYTCEGGFRISEENETTCYMG-KWS-SPPQCEGLPC 357
Query: 707 SDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLST 766
P + SHG + SD+ Y+ G V Y+C +G+ + G +++
Sbjct: 358 KSP------------PEISHG-VVAHMSDS------YQYGEEVTYKCFEGFGIDGPAIAK 398
Query: 767 CEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFY--GATAFYQCDENWELEGVIR 824
C +WS P+C DC + EN + + Y G Y C ++++G
Sbjct: 399 CLGE-KWSHP-PSCIKTDCLSLPSFENA-IPMGEKKDVYKAGEQVTYTCATYYKMDGASN 455
Query: 825 RMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGH 884
C N W+ P C++ +C +P ++ + S G YQC Y + G
Sbjct: 456 VTCI-NSRWTGRPT-CRDTSCVNPPT-VQNAYIVSRQMSKYPSGERVRYQCRSPYEMFGD 512
Query: 885 QTRTCISKGQWNGTVPVCIPID--CRSPGNIENGKIVISNGSTLF-GSSVEYYCLSQYQR 941
+ C++ G W P C C P I+NG I S SSVEY C + YQ
Sbjct: 513 EEVMCLN-GNWTEP-PQCKDSTGKCGPPPPIDNGDITSFPLSVYAPASSVEYQCQNLYQL 570
Query: 942 VGPFLRKCLDDGRWSGEEPSC 962
G C +G+WS E P C
Sbjct: 571 EGNKRITC-RNGQWS-EPPKC 589
Score = 120 bits (290), Expect = 2e-26
Identities = 117/468 (25%), Positives = 193/468 (41%), Gaps = 55/468 (11%)
Query: 332 WN-DVGCNLDYLHWICQYLPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKS 390
W+ +V C++ + Q PP P+ TT L +Y G ++ C E +++ +
Sbjct: 223 WDPEVNCSMAQI----QLCPPPPQIPNSHNMTTTL--NYRDGEKVSVLCQENYLIQEGEE 276
Query: 391 RHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDV---ALIDNRTTHGARALYSCRENFTLVG 447
CK DG W P + + C IE G + HG + Y+C F +
Sbjct: 277 ITCK-DGRWQSIPLCVEKIPCSQPPQIEHGTINSSRSSQESYAHGTKLSYTCEGGFRISE 335
Query: 448 NPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVT--VNGHKAGSLASYTCENGHILSG 505
E TC G W P+C C PP +S+ V + ++ G +Y C G + G
Sbjct: 336 ENETTCY-MGKWSSP-PQCEGLPCKSPPEISHGVVAHMSDSYQYGEEVTYKCFEGFGIDG 393
Query: 506 STSVTCTLGGAWSGVPPSCKYVNCGTPTIHKGSFVLINGTTTY--GSIAQFTCEPDYWLN 563
C LG WS PPSC +C + + + + Y G +TC Y ++
Sbjct: 394 PAIAKC-LGEKWSH-PPSCIKTDCLSLPSFENAIPMGEKKDVYKAGEQVTYTCATYYKMD 451
Query: 564 GAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYM---EAFDYYVHSTINFHCEAGHKL 620
GA + C + +W+ P+C TSC P Y+ + Y + + C + +++
Sbjct: 452 GASNVTCI-NSRWT-GRPTCRDTSCVNPPTVQNAYIVSRQMSKYPSGERVRYQCRSPYEM 509
Query: 621 IGEPNLVCQQDGEWSGDSPTCEYID--CGKLPTLPYGTMELLNGTTHL-GSVIQYSCTTN 677
G+ ++C +G W+ + P C+ CG P + G + + + S ++Y C
Sbjct: 510 FGDEEVMCL-NGNWT-EPPQCKDSTGKCGPPPPIDNGDITSFPLSVYAPASSVEYQCQNL 567
Query: 678 YRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNR 737
Y+L G R TC QWS E +C P V + I+ ++ L T+ +
Sbjct: 568 YQLEGNKRITC-RNGQWS------EPPKCLHPCVISREIM------ENYNIALRWTAKQK 614
Query: 738 DVGNTYRIGALVKYRCEKGYKVIGES---LSTCEDNGQWSGTT--PTC 780
T G V++ C++GY++ S +TC W G PTC
Sbjct: 615 LYSRT---GESVEFVCKRGYRLSSRSHTLRTTC-----WDGKLEYPTC 654
Score = 70.9 bits (166), Expect = 2e-11
Identities = 59/231 (25%), Positives = 103/231 (44%), Gaps = 19/231 (8%)
Query: 743 YRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTC--QYVDCGNPGRIENGKVTLPS 800
Y++G ++K+ C+ G+ ++G + C G S P C Q CG P + NG V +
Sbjct: 13 YKVGEVLKFSCKPGFTIVGPNSVQCYHFG-LSPDLPICKEQVQSCGPPPELLNGNVKEKT 71
Query: 801 NATF-YGATAFYQCDENWELEGVIRRMCQENGTWSLEPP-ICKEITCPDPSAQIKAGSGL 858
+ + Y C+ + ++G + C + G W+ P I +E TC D +++ G
Sbjct: 72 KEEYGHSEVVEYYCNPRFLMKGPNKIQCVD-GEWTTLPVCIVEESTCGD-IPELEHGWAQ 129
Query: 859 LVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPID----CRSPGNIE 914
L + G + C + + GH++ TCI G W +P C+ ID C+S I
Sbjct: 130 L-SSPPYYYGDSVEFNCSESFTMIGHRSITCI-HGVWT-QLPQCVAIDKLKKCKSSNLII 186
Query: 915 NGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCELA 965
+ + + S++ Y C + G C+ +GRW E +C +A
Sbjct: 187 LEEHLKNKKEFDHNSNIRYRCRG---KEGWIHTVCI-NGRWD-PEVNCSMA 232
Score = 37.9 bits (84), Expect = 0.20
Identities = 20/57 (35%), Positives = 27/57 (47%), Gaps = 2/57 (3%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C +P NA + +G Y+C YE+FG + C L G+WT EPP C
Sbjct: 474 CVNPPTVQNAYIVSRQMSKYPSGERVRYQCRSPYEMFGDEEVMC-LNGNWT-EPPQC 528
>DQ233256-1|ABB02180.1| 1231|Homo sapiens complement factor H protein.
Length = 1231
Score = 169 bits (410), Expect = 6e-41
Identities = 161/618 (26%), Positives = 252/618 (40%), Gaps = 55/618 (8%)
Query: 345 ICQYLPPTCGSPDKLLNTTI---LGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSG 401
IC+ +CG P +LLN + +Y + Y C ++ G C DG W+
Sbjct: 622 ICKEQVQSCGPPPELLNGNVKEKTKEEYGHSEVVEYYCNPRFLMKGPNKIQCV-DGEWTT 680
Query: 402 APPSC-KYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWD 460
P + CG + +E G L +G ++C E+FT++G+ TC G+W
Sbjct: 681 LPVCIVEESTCGDIPELEHGWAQLSSPPYYYGDSVEFNCSESFTMIGHRSITC-IHGVWT 739
Query: 461 GEAPRCLFDWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSV--TCTLGGAWS 518
+ P+C+ SN + K + + G T + G W
Sbjct: 740 -QLPQCVAIDKLKKCKSSNLIILEEHLKNKKEFDHNSNIRYRCRGKEGWIHTVCINGRWD 798
Query: 519 G-VPPSCKYVNCGTPTIHKGSFVLINGTTTY--GSIAQFTCEPDYWLNGAEELVCNRDGK 575
V S + P + + T Y G C+ +Y + EE+ C +DG+
Sbjct: 799 PEVNCSMAQIQLCPPPPQIPNSHNMTTTLNYRDGEKVSVLCQENYLIQEGEEITC-KDGR 857
Query: 576 WSYDIPSC-ELTSCPEPEVPSGGYMEAF----DYYVHST-INFHCEAGHKLIGEPNLVCQ 629
W IP C E C +P G + + + Y H T +++ CE G ++ E C
Sbjct: 858 WQ-SIPLCVEKIPCSQPPQIEHGTINSSRSSQESYAHGTKLSYTCEGGFRISEENETTCY 916
Query: 630 QDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCT 689
G+WS P CE + C P + +G + ++ + G + Y C + + GP C
Sbjct: 917 M-GKWSSP-PQCEGLPCKSPPEISHGVVAHMSDSYQYGEEVTYKCFEGFGIDGPAIAKCL 974
Query: 690 EEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALV 749
E +WS P C + C +S+ + + I + +DV Y+ G V
Sbjct: 975 GE-KWSHP-PSCIKTDC----------LSLPSFENA-----IPMGEKKDV---YKAGEQV 1014
Query: 750 KYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATF-YGAT 808
Y C YK+ G S TC N +W+G PTC+ C NP ++N + + + G
Sbjct: 1015 TYTCATYYKMDGASNVTCI-NSRWTGR-PTCRDTSCVNPPTVQNAYIVSRQMSKYPSGER 1072
Query: 809 AFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCP-DPSAQIKAGSGLLVVTSTLSI 867
YQC +E+ G MC NG W+ EPP CK+ T P I G S +
Sbjct: 1073 VRYQCRSPYEMFGDEEVMCL-NGNWT-EPPQCKDSTGKCGPPPPIDNGDITSFPLSVYAP 1130
Query: 868 GGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVI--SNGST 925
YQC+ Y L+G++ TC GQW+ P C+ S +EN I + +
Sbjct: 1131 ASSVEYQCQNLYQLEGNKRITC-RNGQWS-EPPKCLHPCVISREIMENYNIALRWTAKQK 1188
Query: 926 LF---GSSVEYYCLSQYQ 940
L+ G SVE+ C Y+
Sbjct: 1189 LYSRTGESVEFVCKRGYR 1206
Score = 150 bits (363), Expect = 3e-35
Identities = 169/642 (26%), Positives = 249/642 (38%), Gaps = 73/642 (11%)
Query: 346 CQYLPPTCGSP-DKLLNTTIL--GNDYDVGSRIVYKCPEGHMLLGD-KSRHCKKDGFWSG 401
CQ P CG P D T L GN ++ G + VY C EG+ LLG+ R C DG W+
Sbjct: 80 CQKRP--CGHPGDTPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYRECDTDG-WTN 136
Query: 402 APPSCKYVNCGGLTPIEDGDV---ALIDNRTTHGARAL-YSCRENFTLVGNPERTCGDEG 457
P C+ V C +T E+G + A+ +R H +A+ + C + + G+ E C D+G
Sbjct: 137 DIPICEVVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCSDDG 196
Query: 458 IWDGEAPRCLFDWCPDPPAVSNASVTVN-GHKAGSLASYTCENGHILSGSTSVTCTLGGA 516
W E P+C+ C P ++ + ++ +K Y C G+ S CT G
Sbjct: 197 FWSKEKPKCVEISCKSPDVINGSPISQKIIYKENERFQYKCNMGYEYSERGDAVCTESG- 255
Query: 517 WSGVPPSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYW-LNGAEELVCNRDGK 575
W + PSC+ +C P I G + + G + C ++ C G
Sbjct: 256 WRPL-PSCEEKSCDNPYIPNGDYSPLRIKHRTGDEITYQCRNGFYPATRGNTAKCTSTG- 313
Query: 576 WSYDIPSCELTSCPEPEVPSGG-YME-----AFDYYVHSTINFHCEAGHKLIGE---PNL 626
W P C L C P++ GG Y E F V +++C+ + ++
Sbjct: 314 W-IPAPRCTLKPCDYPDIKHGGLYHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDHI 372
Query: 627 VCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRR 686
C QDG WS P C P L G + G I +C Y L
Sbjct: 373 HCTQDG-WSPAVPCLR--KC-YFPYLENGYNQNYGRKFVQGKSIDVACHPGYALPKAQTT 428
Query: 687 TCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIG 746
E WS +PRC ++ KS + + S TY +
Sbjct: 429 VTCMENGWS-PTPRCIRVK-----TCSKSSIDIENGFISESQ------------YTYALK 470
Query: 747 ALVKYRCEKGYKVI-GESLS--TCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNAT 803
KY+C+ GY GE+ TC +G WS PTC C P N +
Sbjct: 471 EKAKYQCKLGYVTADGETSGSITCGKDG-WS-AQPTC-IKSCDIP-VFMNARTKNDFTWF 526
Query: 804 FYGATAFYQCDENWE-----LEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGL 858
T Y+C + +E G I +C NG WS + PIC E C P +
Sbjct: 527 KLNDTLDYECHDGYESNTGSTTGSI--VCGYNG-WS-DLPICYERECELPKIDVHLVPDR 582
Query: 859 LVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIP--IDCRSPGNIENG 916
+G + C+ G+ + G + C G + +P+C C P + NG
Sbjct: 583 --KKDQYKVGEVLKFSCKPGFTIVGPNSVQCYHFG-LSPDLPICKEQVQSCGPPPELLNG 639
Query: 917 KIVISNGSTLFGSS--VEYYCLSQYQRVGPFLRKCLDDGRWS 956
V +G S VEYYC ++ GP +C+ DG W+
Sbjct: 640 N-VKEKTKEEYGHSEVVEYYCNPRFLMKGPNKIQCV-DGEWT 679
Score = 145 bits (352), Expect = 7e-34
Identities = 159/620 (25%), Positives = 256/620 (41%), Gaps = 61/620 (9%)
Query: 366 GNDYDVGSRIVYKCPEGHML-LGDKSRHCKKDGFWSGAPPSCKYVNCGGLT-PIEDGDVA 423
G + G I C G+ L + C ++G WS P + C + IE+G ++
Sbjct: 403 GRKFVQGKSIDVACHPGYALPKAQTTVTCMENG-WSPTPRCIRVKTCSKSSIDIENGFIS 461
Query: 424 LIDNRTTHGARALYSCRENFTLVGNPER---TCGDEGIWDGEAPRCLFDWCPDPPAVSNA 480
+A Y C+ + TCG +G W + P C+ C D P NA
Sbjct: 462 ESQYTYALKEKAKYQCKLGYVTADGETSGSITCGKDG-WSAQ-PTCIKS-C-DIPVFMNA 517
Query: 481 SVT--VNGHKAGSLASYTCENGHILS-GST--SVTCTLGGAWSGVPPSCKYVNCGTPTIH 535
K Y C +G+ + GST S+ C G WS +P C C P I
Sbjct: 518 RTKNDFTWFKLNDTLDYECHDGYESNTGSTTGSIVCGYNG-WSDLP-ICYERECELPKID 575
Query: 536 KGSFVLINGTTTY--GSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSC--ELTSC-PE 590
V Y G + +F+C+P + + G + C G S D+P C ++ SC P
Sbjct: 576 V-HLVPDRKKDQYKVGEVLKFSCKPGFTIVGPNSVQCYHFGL-SPDLPICKEQVQSCGPP 633
Query: 591 PEVPSGGYMEAF-DYYVHS-TINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTC--EYIDC 646
PE+ +G E + Y HS + ++C + G PN + DGEW+ P C E C
Sbjct: 634 PELLNGNVKEKTKEEYGHSEVVEYYCNPRFLMKG-PNKIQCVDGEWT-TLPVCIVEESTC 691
Query: 647 GKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRC 706
G +P L +G +L + + G ++++C+ ++ ++G TC W+ P+C
Sbjct: 692 GDIPELEHGWAQLSSPPYYYGDSVEFNCSESFTMIGHRSITCIHGV-WT-QLPQC----- 744
Query: 707 SDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLST 766
V++ + LI ++ + + ++YRC +G + G +
Sbjct: 745 ----------VAIDKLKKCKSSNLIILEEHLKNKKEFDHNSNIRYRC-RGKE--GWIHTV 791
Query: 767 CEDNGQWSG--TTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIR 824
C NG+W Q C P +I N + G C EN+ ++
Sbjct: 792 C-INGRWDPEVNCSMAQIQLCPPPPQIPNSHNMTTTLNYRDGEKVSVLCQENYLIQEGEE 850
Query: 825 RMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSI--GGEAHYQCERGYNLK 882
C++ G W P ++I C P QI+ G+ +S S G + Y CE G+ +
Sbjct: 851 ITCKD-GRWQSIPLCVEKIPCSQP-PQIEHGTINSSRSSQESYAHGTKLSYTCEGGFRIS 908
Query: 883 GHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRV 942
TC G+W+ + P C + C+SP I +G + + S +G V Y C +
Sbjct: 909 EENETTCY-MGKWS-SPPQCEGLPCKSPPEISHGVVAHMSDSYQYGEEVTYKCFEGFGID 966
Query: 943 GPFLRKCLDDGRWSGEEPSC 962
GP + KCL + +WS PSC
Sbjct: 967 GPAIAKCLGE-KWS-HPPSC 984
Score = 139 bits (336), Expect = 6e-32
Identities = 144/585 (24%), Positives = 226/585 (38%), Gaps = 66/585 (11%)
Query: 345 ICQYLPPTCGSPDKLLN--TTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGA 402
+C TCG +L + + Y G + + C E ++G +S C G W+
Sbjct: 683 VCIVEESTCGDIPELEHGWAQLSSPPYYYGDSVEFNCSESFTMIGHRSITCIH-GVWTQL 741
Query: 403 PPSC---KYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIW 459
P K C I + H + Y CR + T G W
Sbjct: 742 PQCVAIDKLKKCKSSNLIILEEHLKNKKEFDHNSNIRYRCRGKEGWI----HTVCINGRW 797
Query: 460 DGEAPRCL--FDWCPDPPAVSNAS--VTVNGHKAGSLASYTCENGHILSGSTSVTCTLGG 515
D E + CP PP + N+ T ++ G S C+ +++ +TC G
Sbjct: 798 DPEVNCSMAQIQLCPPPPQIPNSHNMTTTLNYRDGEKVSVLCQENYLIQEGEEITCK-DG 856
Query: 516 AWSGVPPSCKYVNCGTPT-IHKGSFVLINGTT---TYGSIAQFTCEPDYWLNGAEELVCN 571
W +P + + C P I G+ + +G+ +TCE + ++ E C
Sbjct: 857 RWQSIPLCVEKIPCSQPPQIEHGTINSSRSSQESYAHGTKLSYTCEGGFRISEENETTCY 916
Query: 572 RDGKWSYDIPSCELTSCPEP-EVPSGGYMEAFDYYVHST-INFHCEAGHKLIGEPNLVCQ 629
GKWS P CE C P E+ G D Y + + + C G + G C
Sbjct: 917 M-GKWSSP-PQCEGLPCKSPPEISHGVVAHMSDSYQYGEEVTYKCFEGFGIDGPAIAKCL 974
Query: 630 QDGEWSGDSPTCEYIDCGKLPTLPYGT-MELLNGTTHLGSVIQYSCTTNYRLVGPVRRTC 688
+ +WS P+C DC LP+ M G + Y+C T Y++ G TC
Sbjct: 975 GE-KWS-HPPSCIKTDCLSLPSFENAIPMGEKKDVYKAGEQVTYTCATYYKMDGASNVTC 1032
Query: 689 TEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGAL 748
+W+ P C + C +P + + + +R + + Y G
Sbjct: 1033 INS-RWT-GRPTCRDTSCVNPPTVQNAYIV-----------------SRQM-SKYPSGER 1072
Query: 749 VKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQ--YVDCGNPGRIENGKVT-LPSNATFY 805
V+Y+C Y++ G+ C NG W+ P C+ CG P I+NG +T P +
Sbjct: 1073 VRYQCRSPYEMFGDEEVMCL-NGNWT-EPPQCKDSTGKCGPPPPIDNGDITSFPLSVYAP 1130
Query: 806 GATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTL 865
++ YQC ++LEG R C+ NG WS EPP C C ++ + L T+
Sbjct: 1131 ASSVEYQCQNLYQLEGNKRITCR-NGQWS-EPPKCLH-PCVISREIMENYNIALRWTAKQ 1187
Query: 866 SI----GGEAHYQCERGYNL--KGHQTRTCISKGQWNGTV--PVC 902
+ G + C+RGY L + H RT W+G + P C
Sbjct: 1188 KLYSRTGESVEFVCKRGYRLSSRSHTLRTTC----WDGKLEYPTC 1228
Score = 138 bits (334), Expect = 1e-31
Identities = 141/551 (25%), Positives = 216/551 (39%), Gaps = 56/551 (10%)
Query: 437 YSCRENFTLVGNPERTCGDEGIWDGEAPRCL--FDWCPDPPAVSNASV---TVNGHKAGS 491
+SC+ FT+VG C G+ + P C C PP + N +V T +
Sbjct: 595 FSCKPGFTIVGPNSVQCYHFGL-SPDLPICKEQVQSCGPPPELLNGNVKEKTKEEYGHSE 653
Query: 492 LASYTCENGHILSGSTSVTCTLGGAWSGVPPSC-KYVNCGT-PTIHKGSFVLINGTTTYG 549
+ Y C ++ G + C + G W+ +P + CG P + G L + YG
Sbjct: 654 VVEYYCNPRFLMKGPNKIQC-VDGEWTTLPVCIVEESTCGDIPELEHGWAQLSSPPYYYG 712
Query: 550 SIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSC----ELTSCPEPE--VPSGGYMEAFD 603
+F C + + G + C G W+ +P C +L C + +
Sbjct: 713 DSVEFNCSESFTMIGHRSITCIH-GVWT-QLPQCVAIDKLKKCKSSNLIILEEHLKNKKE 770
Query: 604 YYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYID---CGKLPTLPYGTMELL 660
+ +S I + C I + VC +G W + C C P +P
Sbjct: 771 FDHNSNIRYRCRGKEGWI---HTVCI-NGRWDPEV-NCSMAQIQLCPPPPQIPNSHNMTT 825
Query: 661 NGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRC-EEIRCSDPIVAEKSIVSV 719
G + C NY + TC ++ +W S P C E+I CS P E
Sbjct: 826 TLNYRDGEKVSVLCQENYLIQEGEEITC-KDGRWQ-SIPLCVEKIPCSQPPQIE------ 877
Query: 720 TGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPT 779
H I +S R +Y G + Y CE G+++ E+ +TC G+WS + P
Sbjct: 878 --------HGTINSS--RSSQESYAHGTKLSYTCEGGFRISEENETTCY-MGKWS-SPPQ 925
Query: 780 CQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPI 839
C+ + C +P I +G V S++ YG Y+C E + ++G C WS PP
Sbjct: 926 CEGLPCKSPPEISHGVVAHMSDSYQYGEEVTYKCFEGFGIDGPAIAKCL-GEKWS-HPPS 983
Query: 840 CKEITCPD-PSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGT 898
C + C PS + G G + Y C Y + G TCI+ +W G
Sbjct: 984 CIKTDCLSLPSFENAIPMG--EKKDVYKAGEQVTYTCATYYKMDGASNVTCIN-SRWTGR 1040
Query: 899 VPVCIPIDCRSPGNIENGKIVISNGSTL-FGSSVEYYCLSQYQRVGPFLRKCLDDGRWSG 957
P C C +P ++N IV S G V Y C S Y+ G CL +G W+
Sbjct: 1041 -PTCRDTSCVNPPTVQNAYIVSRQMSKYPSGERVRYQCRSPYEMFGDEEVMCL-NGNWT- 1097
Query: 958 EEPSCELATNE 968
E P C+ +T +
Sbjct: 1098 EPPQCKDSTGK 1108
Score = 135 bits (326), Expect = 9e-31
Identities = 154/621 (24%), Positives = 251/621 (40%), Gaps = 67/621 (10%)
Query: 367 NDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCK--YVNCGGLTPIEDGDVA- 423
+ Y VG + + C G ++G S C G S P CK +CG + +G+V
Sbjct: 585 DQYKVGEVLKFSCKPGFTIVGPNSVQCYHFGL-SPDLPICKEQVQSCGPPPELLNGNVKE 643
Query: 424 LIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFD--WCPDPPAVSN-- 479
H Y C F + G + C D G W P C+ + C D P + +
Sbjct: 644 KTKEEYGHSEVVEYYCNPRFLMKGPNKIQCVD-GEWT-TLPVCIVEESTCGDIPELEHGW 701
Query: 480 ASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSC---KYVNCGTPTIHK 536
A ++ + G + C + G S+TC + G W+ +P K C + +
Sbjct: 702 AQLSSPPYYYGDSVEFNCSESFTMIGHRSITC-IHGVWTQLPQCVAIDKLKKCKSSNLII 760
Query: 537 GSFVLINGTT-TYGSIAQFTCE-PDYWLNGAEELVCNRDGKWSYDIPSCELTS---CPEP 591
L N + S ++ C + W++ VC +G+W ++ +C + CP P
Sbjct: 761 LEEHLKNKKEFDHNSNIRYRCRGKEGWIH----TVCI-NGRWDPEV-NCSMAQIQLCPPP 814
Query: 592 -EVPSGGYMEA-FDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKL 649
++P+ M +Y ++ C+ + LI E + +DG W E I C +
Sbjct: 815 PQIPNSHNMTTTLNYRDGEKVSVLCQENY-LIQEGEEITCKDGRWQSIPLCVEKIPCSQP 873
Query: 650 PTLPYGTMELLNGTTHL---GSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRC 706
P + +GT+ + G+ + Y+C +R+ TC +WS S P+CE + C
Sbjct: 874 PQIEHGTINSSRSSQESYAHGTKLSYTCEGGFRISEENETTCYMG-KWS-SPPQCEGLPC 931
Query: 707 SDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLST 766
P + SHG + SD+ Y+ G V Y+C +G+ + G +++
Sbjct: 932 KSP------------PEISHG-VVAHMSDS------YQYGEEVTYKCFEGFGIDGPAIAK 972
Query: 767 CEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFY--GATAFYQCDENWELEGVIR 824
C +WS P+C DC + EN + + Y G Y C ++++G
Sbjct: 973 CLGE-KWSHP-PSCIKTDCLSLPSFENA-IPMGEKKDVYKAGEQVTYTCATYYKMDGASN 1029
Query: 825 RMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGH 884
C N W+ P C++ +C +P ++ + S G YQC Y + G
Sbjct: 1030 VTCI-NSRWTGRPT-CRDTSCVNPPT-VQNAYIVSRQMSKYPSGERVRYQCRSPYEMFGD 1086
Query: 885 QTRTCISKGQWNGTVPVCIPID--CRSPGNIENGKIVISNGSTLF-GSSVEYYCLSQYQR 941
+ C++ G W P C C P I+NG I S SSVEY C + YQ
Sbjct: 1087 EEVMCLN-GNWTEP-PQCKDSTGKCGPPPPIDNGDITSFPLSVYAPASSVEYQCQNLYQL 1144
Query: 942 VGPFLRKCLDDGRWSGEEPSC 962
G C +G+WS E P C
Sbjct: 1145 EGNKRITC-RNGQWS-EPPKC 1163
Score = 126 bits (305), Expect = 3e-28
Identities = 155/642 (24%), Positives = 238/642 (37%), Gaps = 62/642 (9%)
Query: 346 CQYLPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPP- 404
C LPP + ++L + Y G++ +YKC G+ LG+ C+K G W P
Sbjct: 21 CNELPPRRNT--EILTGSWSDQTYPEGTQAIYKCRPGYRSLGNIIMVCRK-GEWVALNPL 77
Query: 405 -SCKYVNCG--GLTPIEDGDVALI-DNRTTHGARALYSCRENFTLVGNPE-RTCGDEGIW 459
C+ CG G TP G L N +G +A+Y+C E + L+G R C +G W
Sbjct: 78 RKCQKRPCGHPGDTPF--GTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYRECDTDG-W 134
Query: 460 DGEAPRCLFDWCPDPPAVSNASVTVNG------HKAGSLASYTCENGHILSGSTSVTCTL 513
+ P C C A N + + + G + C +G+ + G + C+
Sbjct: 135 TNDIPICEVVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCSD 194
Query: 514 GGAWSGVPPSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRD 573
G WS P C ++C +P + GS + Q+ C Y + + VC
Sbjct: 195 DGFWSKEKPKCVEISCKSPDVINGSPISQKIIYKENERFQYKCNMGYEYSERGDAVCTES 254
Query: 574 GKWSYDIPSCELTSCPEPEVPSGGYME-AFDYYVHSTINFHCEAGHKLIGEPNLV-CQQD 631
G W +PSCE SC P +P+G Y + I + C G N C
Sbjct: 255 G-WR-PLPSCEEKSCDNPYIPNGDYSPLRIKHRTGDEITYQCRNGFYPATRGNTAKCTST 312
Query: 632 GEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEE 691
G W +P C C P + +G + N V + Y C E
Sbjct: 313 G-WI-PAPRCTLKPC-DYPDIKHGGLYHENMRRPYFPVAVGKYYSYY---------CDEH 360
Query: 692 FQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKY 751
F+ + S + I C+ + R + N++ G + G +
Sbjct: 361 FE-TPSGSYWDHIHCT-----QDGWSPAVPCLRKCYFPYLENGYNQNYGRKFVQGKSIDV 414
Query: 752 RCEKGYKV-IGESLSTCEDNGQWSGTTPTCQYVDCGNPG-RIENGKVTLPSNATFYGATA 809
C GY + ++ TC +NG WS T + C IENG ++ A
Sbjct: 415 ACHPGYALPKAQTTVTCMENG-WSPTPRCIRVKTCSKSSIDIENGFISESQYTYALKEKA 473
Query: 810 FYQCDENW-----ELEGVIRRMCQENGTWSLEPPICKEITCP-DPSAQIKAGSGLLVVTS 863
YQC + E G I C ++G WS +P K P +A+ K +
Sbjct: 474 KYQCKLGYVTADGETSGSI--TCGKDG-WSAQPTCIKSCDIPVFMNARTKNDFTWFKLND 530
Query: 864 TLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNG--TVPVCIPIDCRSPGNIENGKIVIS 921
TL Y+C GY T I G +NG +P+C +C P +
Sbjct: 531 TLD------YECHDGYESNTGSTTGSIVCG-YNGWSDLPICYERECELPKIDVHLVPDRK 583
Query: 922 NGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
G +++ C + VGP +C G S + P C+
Sbjct: 584 KDQYKVGEVLKFSCKPGFTIVGPNSVQCYHFG-LSPDLPICK 624
Score = 120 bits (290), Expect = 2e-26
Identities = 117/468 (25%), Positives = 193/468 (41%), Gaps = 55/468 (11%)
Query: 332 WN-DVGCNLDYLHWICQYLPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKS 390
W+ +V C++ + Q PP P+ TT L +Y G ++ C E +++ +
Sbjct: 797 WDPEVNCSMAQI----QLCPPPPQIPNSHNMTTTL--NYRDGEKVSVLCQENYLIQEGEE 850
Query: 391 RHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDV---ALIDNRTTHGARALYSCRENFTLVG 447
CK DG W P + + C IE G + HG + Y+C F +
Sbjct: 851 ITCK-DGRWQSIPLCVEKIPCSQPPQIEHGTINSSRSSQESYAHGTKLSYTCEGGFRISE 909
Query: 448 NPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVT--VNGHKAGSLASYTCENGHILSG 505
E TC G W P+C C PP +S+ V + ++ G +Y C G + G
Sbjct: 910 ENETTCY-MGKWSSP-PQCEGLPCKSPPEISHGVVAHMSDSYQYGEEVTYKCFEGFGIDG 967
Query: 506 STSVTCTLGGAWSGVPPSCKYVNCGTPTIHKGSFVLINGTTTY--GSIAQFTCEPDYWLN 563
C LG WS PPSC +C + + + + Y G +TC Y ++
Sbjct: 968 PAIAKC-LGEKWSH-PPSCIKTDCLSLPSFENAIPMGEKKDVYKAGEQVTYTCATYYKMD 1025
Query: 564 GAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYM---EAFDYYVHSTINFHCEAGHKL 620
GA + C + +W+ P+C TSC P Y+ + Y + + C + +++
Sbjct: 1026 GASNVTCI-NSRWT-GRPTCRDTSCVNPPTVQNAYIVSRQMSKYPSGERVRYQCRSPYEM 1083
Query: 621 IGEPNLVCQQDGEWSGDSPTCEYID--CGKLPTLPYGTMELLNGTTHL-GSVIQYSCTTN 677
G+ ++C +G W+ + P C+ CG P + G + + + S ++Y C
Sbjct: 1084 FGDEEVMCL-NGNWT-EPPQCKDSTGKCGPPPPIDNGDITSFPLSVYAPASSVEYQCQNL 1141
Query: 678 YRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNR 737
Y+L G R TC QWS E +C P V + I+ ++ L T+ +
Sbjct: 1142 YQLEGNKRITC-RNGQWS------EPPKCLHPCVISREIM------ENYNIALRWTAKQK 1188
Query: 738 DVGNTYRIGALVKYRCEKGYKVIGES---LSTCEDNGQWSGTT--PTC 780
T G V++ C++GY++ S +TC W G PTC
Sbjct: 1189 LYSRT---GESVEFVCKRGYRLSSRSHTLRTTC-----WDGKLEYPTC 1228
Score = 117 bits (282), Expect = 2e-25
Identities = 131/520 (25%), Positives = 194/520 (37%), Gaps = 51/520 (9%)
Query: 406 CKYVNCGGLTPIEDGDV---ALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGE 462
C +C L P + ++ + D G +A+Y CR + +GN C +G W
Sbjct: 16 CVAEDCNELPPRRNTEILTGSWSDQTYPEGTQAIYKCRPGYRSLGNIIMVCR-KGEWVAL 74
Query: 463 AP--RCLFDWCPDPPAVSNASVTVNGHKA---GSLASYTCENGHILSGSTSVT-CTLGGA 516
P +C C P + T+ G G A YTC G+ L G + C G
Sbjct: 75 NPLRKCQKRPCGHPGDTPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYRECDTDG- 133
Query: 517 WSGVPPSCKYVNCGTPTIHKGSFVLINGTTT-----YGSIAQFTCEPDYWLNGAEELVCN 571
W+ P C+ V C T + ++ + +G +F C Y + G EE+ C+
Sbjct: 134 WTNDIPICEVVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCS 193
Query: 572 RDGKWSYDIPSCELTSCPEPEVPSGG-YMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQ 630
DG WS + P C SC P+V +G + Y + + C G++ + VC +
Sbjct: 194 DDGFWSKEKPKCVEISCKSPDVINGSPISQKIIYKENERFQYKCNMGYEYSERGDAVCTE 253
Query: 631 DGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTN-YRLVGPVRRTCT 689
G W P+CE C P +P G L G I Y C Y CT
Sbjct: 254 SG-WR-PLPSCEEKSCDN-PYIPNGDYSPLRIKHRTGDEITYQCRNGFYPATRGNTAKCT 310
Query: 690 EEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALV 749
W +PRC C P D HG + + R +G
Sbjct: 311 ST-GWI-PAPRCTLKPCDYP-------------DIKHGG--LYHENMRRPYFPVAVGKYY 353
Query: 750 KYRCEKGYKVIGESL---STCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYG 806
Y C++ ++ S C +G WS P + C P +ENG G
Sbjct: 354 SYYCDEHFETPSGSYWDHIHCTQDG-WSPAVPCLR--KCYFP-YLENGYNQNYGRKFVQG 409
Query: 807 ATAFYQCDENWEL-EGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTL 865
+ C + L + C ENG WS P + TC S I+ G + T
Sbjct: 410 KSIDVACHPGYALPKAQTTVTCMENG-WSPTPRCIRVKTCSKSSIDIENGF-ISESQYTY 467
Query: 866 SIGGEAHYQCERGYNLKGHQTRTCISKGQ--WNGTVPVCI 903
++ +A YQC+ GY +T I+ G+ W+ P CI
Sbjct: 468 ALKEKAKYQCKLGYVTADGETSGSITCGKDGWSAQ-PTCI 506
Score = 113 bits (273), Expect = 2e-24
Identities = 156/645 (24%), Positives = 247/645 (38%), Gaps = 70/645 (10%)
Query: 345 ICQYLPPTCGSPDKLLNTTILGN-DYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAP 403
+ + LP T K++++ + + +Y G + + C G+ + GD+ HC DGFWS
Sbjct: 143 VVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCSDDGFWSKEK 202
Query: 404 PSCKYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEA 463
P C ++C I ++ R Y C + + C + G W
Sbjct: 203 PKCVEISCKSPDVINGSPISQ-KIIYKENERFQYKCNMGYEYSERGDAVCTESG-W-RPL 259
Query: 464 PRCLFDWCPDPPAVSNA--SVTVNGHKAGSLASYTCENG-HILSGSTSVTCTLGGAWSGV 520
P C C D P + N S H+ G +Y C NG + + + CT G W +
Sbjct: 260 PSCEEKSC-DNPYIPNGDYSPLRIKHRTGDEITYQCRNGFYPATRGNTAKCTSTG-W--I 315
Query: 521 P-PSCKYVNCGTPTIHKGSFVLINGTTTY-----GSIAQFTCEPDYWL-NGA--EELVCN 571
P P C C P I G N Y G + C+ + +G+ + + C
Sbjct: 316 PAPRCTLKPCDYPDIKHGGLYHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDHIHCT 375
Query: 572 RDGKWSYDIPSCELTSCPEPEVPSGGYMEAFDYYVH-STINFHCEAGHKL-IGEPNLVCQ 629
+DG WS +P C L C P + +G +V +I+ C G+ L + + C
Sbjct: 376 QDG-WSPAVP-C-LRKCYFPYLENGYNQNYGRKFVQGKSIDVACHPGYALPKAQTTVTCM 432
Query: 630 QDGEWSGDSPTCEYI-DCGKLP-TLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRR- 686
++G WS +P C + C K + G + T L +Y C Y
Sbjct: 433 ENG-WS-PTPRCIRVKTCSKSSIDIENGFISESQYTYALKEKAKYQCKLGYVTADGETSG 490
Query: 687 --TCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYR 744
TC ++ WS + P C + C P+ + T ND T + +D D
Sbjct: 491 SITCGKD-GWS-AQPTCIK-SCDIPVFMN----ARTKND----FTWFKLNDTLD------ 533
Query: 745 IGALVKYRCEKGYKVIGESLS---TCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSN 801
Y C GY+ S + C NG WS P C +C P +I+ V
Sbjct: 534 ------YECHDGYESNTGSTTGSIVCGYNG-WS-DLPICYERECELP-KIDVHLVPDRKK 584
Query: 802 ATF-YGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKE-ITCPDPSAQIKAGSGLL 859
+ G + C + + G C G S + PICKE + P ++ G+
Sbjct: 585 DQYKVGEVLKFSCKPGFTIVGPNSVQCYHFGL-SPDLPICKEQVQSCGPPPELLNGNVKE 643
Query: 860 VVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPID--CRSPGNIENGK 917
Y C + +KG C+ G+W T+PVCI + C +E+G
Sbjct: 644 KTKEEYGHSEVVEYYCNPRFLMKGPNKIQCVD-GEWT-TLPVCIVEESTCGDIPELEHGW 701
Query: 918 IVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
+S+ +G SVE+ C + +G C+ G W+ + P C
Sbjct: 702 AQLSSPPYYYGDSVEFNCSESFTMIGHRSITCI-HGVWT-QLPQC 744
Score = 111 bits (268), Expect = 1e-23
Identities = 158/643 (24%), Positives = 245/643 (38%), Gaps = 74/643 (11%)
Query: 352 TCGSPDKLLNTTILGND-YDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVN 410
+C SPD + + I Y R YKC G+ C + G W P SC+ +
Sbjct: 209 SCKSPDVINGSPISQKIIYKENERFQYKCNMGYEYSERGDAVCTESG-WRPLP-SCEEKS 266
Query: 411 CGGLTPIEDGDVALIDNRTTHGARALYSCRENF--TLVGNPERTCGDEGIWDGEAPRCLF 468
C I +GD + + + G Y CR F GN + C G W APRC
Sbjct: 267 CDN-PYIPNGDYSPLRIKHRTGDEITYQCRNGFYPATRGNTAK-CTSTG-WI-PAPRCTL 322
Query: 469 DWCPDPPAVSNASVTVNGHK------AGSLASYTC-ENGHILSGS--TSVTCTLGGAWSG 519
C P N + G SY C E+ SGS + CT G WS
Sbjct: 323 KPCDYPDIKHGGLYHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDHIHCTQDG-WSP 381
Query: 520 VPPSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYD 579
P + C P + G G C P Y L A+ V + WS
Sbjct: 382 AVPCLR--KCYFPYLENGYNQNYGRKFVQGKSIDVACHPGYALPKAQTTVTCMENGWS-P 438
Query: 580 IPSC-ELTSCPEP--EVPSGGYMEA-FDYYVHSTINFHCEAGHKLI-GEPN--LVCQQDG 632
P C + +C + ++ +G E+ + Y + + C+ G+ GE + + C +DG
Sbjct: 439 TPRCIRVKTCSKSSIDIENGFISESQYTYALKEKAKYQCKLGYVTADGETSGSITCGKDG 498
Query: 633 EWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRL-VGPVRRTCTEE 691
WS PTC I +P + L + Y C Y G +
Sbjct: 499 -WSAQ-PTC--IKSCDIPVFMNARTKNDFTWFKLNDTLDYECHDGYESNTGSTTGSIVCG 554
Query: 692 FQ-WSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVK 750
+ WSD P C E C P + + +V D+ Y++G ++K
Sbjct: 555 YNGWSDL-PICYERECELPKI-DVHLVPDRKKDQ------------------YKVGEVLK 594
Query: 751 YRCEKGYKVIGESLSTCEDNGQWSGTTPTC--QYVDCGNPGRIENGKVTLPSNATF-YGA 807
+ C+ G+ ++G + C G S P C Q CG P + NG V + + +
Sbjct: 595 FSCKPGFTIVGPNSVQCYHFG-LSPDLPICKEQVQSCGPPPELLNGNVKEKTKEEYGHSE 653
Query: 808 TAFYQCDENWELEGVIRRMCQENGTWSLEPP-ICKEITCPDPSAQIKAGSGLLVVTSTLS 866
Y C+ + ++G + C + G W+ P I +E TC D +++ G L +
Sbjct: 654 VVEYYCNPRFLMKGPNKIQCVD-GEWTTLPVCIVEESTCGD-IPELEHGWAQL-SSPPYY 710
Query: 867 IGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPID----CRSPGNIENGKIVISN 922
G + C + + GH++ TCI G W +P C+ ID C+S I + + +
Sbjct: 711 YGDSVEFNCSESFTMIGHRSITCI-HGVWT-QLPQCVAIDKLKKCKSSNLIILEEHLKNK 768
Query: 923 GSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCELA 965
S++ Y C + G C+ +GRW E +C +A
Sbjct: 769 KEFDHNSNIRYRCRG---KEGWIHTVCI-NGRWD-PEVNCSMA 806
Score = 93.9 bits (223), Expect = 3e-18
Identities = 85/337 (25%), Positives = 126/337 (37%), Gaps = 43/337 (12%)
Query: 641 CEYIDCGKLPTLPYGTMELLNG-----TTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWS 695
C DC +LP P E+L G T G+ Y C YR +G + C + +W
Sbjct: 16 CVAEDCNELP--PRRNTEILTGSWSDQTYPEGTQAIYKCRPGYRSLGNIIMVCRKG-EWV 72
Query: 696 DSSP--RCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRC 753
+P +C++ C P ++TG GN + G Y C
Sbjct: 73 ALNPLRKCQKRPCGHPGDTPFGTFTLTG------------------GNVFEYGVKAVYTC 114
Query: 754 EKGYKVIGE-SLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTL----PSNATFYGAT 808
+GY+++GE + C+ +G W+ P C+ V C ENGK+ P +G
Sbjct: 115 NEGYQLLGEINYRECDTDG-WTNDIPICEVVKCLPVTAPENGKIVSSAMEPDREYHFGQA 173
Query: 809 AFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIG 868
+ C+ +++EG C ++G WS E P C EI+C P + ++
Sbjct: 174 VRFVCNSGYKIEGDEEMHCSDDGFWSKEKPKCVEISCKSPDVINGSPISQKIIYKE---N 230
Query: 869 GEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFG 928
Y+C GY C G W +P C C +P I NG G
Sbjct: 231 ERFQYKCNMGYEYSERGDAVCTESG-WR-PLPSCEEKSCDNP-YIPNGDYSPLRIKHRTG 287
Query: 929 SSVEYYCLSQ-YQRVGPFLRKCLDDGRWSGEEPSCEL 964
+ Y C + Y KC G W P C L
Sbjct: 288 DEITYQCRNGFYPATRGNTAKCTSTG-WI-PAPRCTL 322
Score = 45.6 bits (103), Expect = 0.001
Identities = 23/58 (39%), Positives = 28/58 (48%), Gaps = 2/58 (3%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFG-ARQRECTLRGDWTLEPPFC 58
CGHP P ++ G AVY C+EGY+L G REC G WT + P C
Sbjct: 85 CGHPGDTPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYRECDTDG-WTNDIPIC 141
Score = 37.9 bits (84), Expect = 0.20
Identities = 20/57 (35%), Positives = 27/57 (47%), Gaps = 2/57 (3%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C +P NA + +G Y+C YE+FG + C L G+WT EPP C
Sbjct: 1048 CVNPPTVQNAYIVSRQMSKYPSGERVRYQCRSPYEMFGDEEVMC-LNGNWT-EPPQC 1102
>AL049744-1|CAI19672.1| 1231|Homo sapiens complement factor H protein.
Length = 1231
Score = 169 bits (410), Expect = 6e-41
Identities = 161/618 (26%), Positives = 252/618 (40%), Gaps = 55/618 (8%)
Query: 345 ICQYLPPTCGSPDKLLNTTI---LGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSG 401
IC+ +CG P +LLN + +Y + Y C ++ G C DG W+
Sbjct: 622 ICKEQVQSCGPPPELLNGNVKEKTKEEYGHSEVVEYYCNPRFLMKGPNKIQCV-DGEWTT 680
Query: 402 APPSC-KYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWD 460
P + CG + +E G L +G ++C E+FT++G+ TC G+W
Sbjct: 681 LPVCIVEESTCGDIPELEHGWAQLSSPPYYYGDSVEFNCSESFTMIGHRSITC-IHGVWT 739
Query: 461 GEAPRCLFDWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSV--TCTLGGAWS 518
+ P+C+ SN + K + + G T + G W
Sbjct: 740 -QLPQCVAIDKLKKCKSSNLIILEEHLKNKKEFDHNSNIRYRCRGKEGWIHTVCINGRWD 798
Query: 519 G-VPPSCKYVNCGTPTIHKGSFVLINGTTTY--GSIAQFTCEPDYWLNGAEELVCNRDGK 575
V S + P + + T Y G C+ +Y + EE+ C +DG+
Sbjct: 799 PEVNCSMAQIQLCPPPPQIPNSHNMTTTLNYRDGEKVSVLCQENYLIQEGEEITC-KDGR 857
Query: 576 WSYDIPSC-ELTSCPEPEVPSGGYMEAF----DYYVHST-INFHCEAGHKLIGEPNLVCQ 629
W IP C E C +P G + + + Y H T +++ CE G ++ E C
Sbjct: 858 WQ-SIPLCVEKIPCSQPPQIEHGTINSSRSSQESYAHGTKLSYTCEGGFRISEENETTCY 916
Query: 630 QDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCT 689
G+WS P CE + C P + +G + ++ + G + Y C + + GP C
Sbjct: 917 M-GKWSSP-PQCEGLPCKSPPEISHGVVAHMSDSYQYGEEVTYKCFEGFGIDGPAIAKCL 974
Query: 690 EEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALV 749
E +WS P C + C +S+ + + I + +DV Y+ G V
Sbjct: 975 GE-KWSHP-PSCIKTDC----------LSLPSFENA-----IPMGEKKDV---YKAGEQV 1014
Query: 750 KYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATF-YGAT 808
Y C YK+ G S TC N +W+G PTC+ C NP ++N + + + G
Sbjct: 1015 TYTCATYYKMDGASNVTCI-NSRWTGR-PTCRDTSCVNPPTVQNAYIVSRQMSKYPSGER 1072
Query: 809 AFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCP-DPSAQIKAGSGLLVVTSTLSI 867
YQC +E+ G MC NG W+ EPP CK+ T P I G S +
Sbjct: 1073 VRYQCRSPYEMFGDEEVMCL-NGNWT-EPPQCKDSTGKCGPPPPIDNGDITSFPLSVYAP 1130
Query: 868 GGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVI--SNGST 925
YQC+ Y L+G++ TC GQW+ P C+ S +EN I + +
Sbjct: 1131 ASSVEYQCQNLYQLEGNKRITC-RNGQWS-EPPKCLHPCVISREIMENYNIALRWTAKQK 1188
Query: 926 LF---GSSVEYYCLSQYQ 940
L+ G SVE+ C Y+
Sbjct: 1189 LYSRTGESVEFVCKRGYR 1206
Score = 149 bits (361), Expect = 5e-35
Identities = 169/642 (26%), Positives = 249/642 (38%), Gaps = 73/642 (11%)
Query: 346 CQYLPPTCGSP-DKLLNTTIL--GNDYDVGSRIVYKCPEGHMLLGD-KSRHCKKDGFWSG 401
CQ P CG P D T L GN ++ G + VY C EG+ LLG+ R C DG W+
Sbjct: 80 CQKRP--CGHPGDTPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYRECDTDG-WTN 136
Query: 402 APPSCKYVNCGGLTPIEDGDV---ALIDNRTTHGARAL-YSCRENFTLVGNPERTCGDEG 457
P C+ V C +T E+G + A+ +R H +A+ + C + + G+ E C D+G
Sbjct: 137 DIPICEVVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCSDDG 196
Query: 458 IWDGEAPRCLFDWCPDPPAVSNASVTVN-GHKAGSLASYTCENGHILSGSTSVTCTLGGA 516
W E P+C+ C P ++ + ++ +K Y C G+ S CT G
Sbjct: 197 FWSKEKPKCVEISCKSPDVINGSPISQKIIYKENERFQYKCNMGYEYSERGDAVCTESG- 255
Query: 517 WSGVPPSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYW-LNGAEELVCNRDGK 575
W + PSC+ +C P I G + + G + C ++ C G
Sbjct: 256 WRPL-PSCEEKSCDNPYIPNGDYSPLRIKHRTGDEITYQCRNGFYPATRGNTAKCTSTG- 313
Query: 576 WSYDIPSCELTSCPEPEVPSGG-YME-----AFDYYVHSTINFHCEAGHKLIGE---PNL 626
W P C L C P++ GG Y E F V +++C+ + ++
Sbjct: 314 W-IPAPRCTLKPCDYPDIKHGGLYHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDHI 372
Query: 627 VCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRR 686
C QDG WS P C P L G + G I +C Y L
Sbjct: 373 HCTQDG-WSPAVPCLR--KC-YFPYLENGYNQNHGRKFVQGKSIDVACHPGYALPKAQTT 428
Query: 687 TCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIG 746
E WS +PRC ++ KS + + S TY +
Sbjct: 429 VTCMENGWS-PTPRCIRVK-----TCSKSSIDIENGFISESQ------------YTYALK 470
Query: 747 ALVKYRCEKGYKVI-GESLS--TCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNAT 803
KY+C+ GY GE+ TC +G WS PTC C P N +
Sbjct: 471 EKAKYQCKLGYVTADGETSGSITCGKDG-WS-AQPTC-IKSCDIP-VFMNARTKNDFTWF 526
Query: 804 FYGATAFYQCDENWE-----LEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGL 858
T Y+C + +E G I +C NG WS + PIC E C P +
Sbjct: 527 KLNDTLDYECHDGYESNTGSTTGSI--VCGYNG-WS-DLPICYERECELPKIDVHLVPDR 582
Query: 859 LVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIP--IDCRSPGNIENG 916
+G + C+ G+ + G + C G + +P+C C P + NG
Sbjct: 583 --KKDQYKVGEVLKFSCKPGFTIVGPNSVQCYHFG-LSPDLPICKEQVQSCGPPPELLNG 639
Query: 917 KIVISNGSTLFGSS--VEYYCLSQYQRVGPFLRKCLDDGRWS 956
V +G S VEYYC ++ GP +C+ DG W+
Sbjct: 640 N-VKEKTKEEYGHSEVVEYYCNPRFLMKGPNKIQCV-DGEWT 679
Score = 145 bits (352), Expect = 7e-34
Identities = 159/620 (25%), Positives = 256/620 (41%), Gaps = 61/620 (9%)
Query: 366 GNDYDVGSRIVYKCPEGHML-LGDKSRHCKKDGFWSGAPPSCKYVNCGGLT-PIEDGDVA 423
G + G I C G+ L + C ++G WS P + C + IE+G ++
Sbjct: 403 GRKFVQGKSIDVACHPGYALPKAQTTVTCMENG-WSPTPRCIRVKTCSKSSIDIENGFIS 461
Query: 424 LIDNRTTHGARALYSCRENFTLVGNPER---TCGDEGIWDGEAPRCLFDWCPDPPAVSNA 480
+A Y C+ + TCG +G W + P C+ C D P NA
Sbjct: 462 ESQYTYALKEKAKYQCKLGYVTADGETSGSITCGKDG-WSAQ-PTCIKS-C-DIPVFMNA 517
Query: 481 SVT--VNGHKAGSLASYTCENGHILS-GST--SVTCTLGGAWSGVPPSCKYVNCGTPTIH 535
K Y C +G+ + GST S+ C G WS +P C C P I
Sbjct: 518 RTKNDFTWFKLNDTLDYECHDGYESNTGSTTGSIVCGYNG-WSDLP-ICYERECELPKID 575
Query: 536 KGSFVLINGTTTY--GSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSC--ELTSC-PE 590
V Y G + +F+C+P + + G + C G S D+P C ++ SC P
Sbjct: 576 V-HLVPDRKKDQYKVGEVLKFSCKPGFTIVGPNSVQCYHFGL-SPDLPICKEQVQSCGPP 633
Query: 591 PEVPSGGYMEAF-DYYVHS-TINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTC--EYIDC 646
PE+ +G E + Y HS + ++C + G PN + DGEW+ P C E C
Sbjct: 634 PELLNGNVKEKTKEEYGHSEVVEYYCNPRFLMKG-PNKIQCVDGEWT-TLPVCIVEESTC 691
Query: 647 GKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRC 706
G +P L +G +L + + G ++++C+ ++ ++G TC W+ P+C
Sbjct: 692 GDIPELEHGWAQLSSPPYYYGDSVEFNCSESFTMIGHRSITCIHGV-WT-QLPQC----- 744
Query: 707 SDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLST 766
V++ + LI ++ + + ++YRC +G + G +
Sbjct: 745 ----------VAIDKLKKCKSSNLIILEEHLKNKKEFDHNSNIRYRC-RGKE--GWIHTV 791
Query: 767 CEDNGQWSG--TTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIR 824
C NG+W Q C P +I N + G C EN+ ++
Sbjct: 792 C-INGRWDPEVNCSMAQIQLCPPPPQIPNSHNMTTTLNYRDGEKVSVLCQENYLIQEGEE 850
Query: 825 RMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSI--GGEAHYQCERGYNLK 882
C++ G W P ++I C P QI+ G+ +S S G + Y CE G+ +
Sbjct: 851 ITCKD-GRWQSIPLCVEKIPCSQP-PQIEHGTINSSRSSQESYAHGTKLSYTCEGGFRIS 908
Query: 883 GHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRV 942
TC G+W+ + P C + C+SP I +G + + S +G V Y C +
Sbjct: 909 EENETTCY-MGKWS-SPPQCEGLPCKSPPEISHGVVAHMSDSYQYGEEVTYKCFEGFGID 966
Query: 943 GPFLRKCLDDGRWSGEEPSC 962
GP + KCL + +WS PSC
Sbjct: 967 GPAIAKCLGE-KWS-HPPSC 984
Score = 139 bits (336), Expect = 6e-32
Identities = 144/585 (24%), Positives = 226/585 (38%), Gaps = 66/585 (11%)
Query: 345 ICQYLPPTCGSPDKLLN--TTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGA 402
+C TCG +L + + Y G + + C E ++G +S C G W+
Sbjct: 683 VCIVEESTCGDIPELEHGWAQLSSPPYYYGDSVEFNCSESFTMIGHRSITCIH-GVWTQL 741
Query: 403 PPSC---KYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIW 459
P K C I + H + Y CR + T G W
Sbjct: 742 PQCVAIDKLKKCKSSNLIILEEHLKNKKEFDHNSNIRYRCRGKEGWI----HTVCINGRW 797
Query: 460 DGEAPRCL--FDWCPDPPAVSNAS--VTVNGHKAGSLASYTCENGHILSGSTSVTCTLGG 515
D E + CP PP + N+ T ++ G S C+ +++ +TC G
Sbjct: 798 DPEVNCSMAQIQLCPPPPQIPNSHNMTTTLNYRDGEKVSVLCQENYLIQEGEEITCK-DG 856
Query: 516 AWSGVPPSCKYVNCGTPT-IHKGSFVLINGTT---TYGSIAQFTCEPDYWLNGAEELVCN 571
W +P + + C P I G+ + +G+ +TCE + ++ E C
Sbjct: 857 RWQSIPLCVEKIPCSQPPQIEHGTINSSRSSQESYAHGTKLSYTCEGGFRISEENETTCY 916
Query: 572 RDGKWSYDIPSCELTSCPEP-EVPSGGYMEAFDYYVHST-INFHCEAGHKLIGEPNLVCQ 629
GKWS P CE C P E+ G D Y + + + C G + G C
Sbjct: 917 M-GKWSSP-PQCEGLPCKSPPEISHGVVAHMSDSYQYGEEVTYKCFEGFGIDGPAIAKCL 974
Query: 630 QDGEWSGDSPTCEYIDCGKLPTLPYGT-MELLNGTTHLGSVIQYSCTTNYRLVGPVRRTC 688
+ +WS P+C DC LP+ M G + Y+C T Y++ G TC
Sbjct: 975 GE-KWS-HPPSCIKTDCLSLPSFENAIPMGEKKDVYKAGEQVTYTCATYYKMDGASNVTC 1032
Query: 689 TEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGAL 748
+W+ P C + C +P + + + +R + + Y G
Sbjct: 1033 INS-RWT-GRPTCRDTSCVNPPTVQNAYIV-----------------SRQM-SKYPSGER 1072
Query: 749 VKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQ--YVDCGNPGRIENGKVT-LPSNATFY 805
V+Y+C Y++ G+ C NG W+ P C+ CG P I+NG +T P +
Sbjct: 1073 VRYQCRSPYEMFGDEEVMCL-NGNWT-EPPQCKDSTGKCGPPPPIDNGDITSFPLSVYAP 1130
Query: 806 GATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTL 865
++ YQC ++LEG R C+ NG WS EPP C C ++ + L T+
Sbjct: 1131 ASSVEYQCQNLYQLEGNKRITCR-NGQWS-EPPKCLH-PCVISREIMENYNIALRWTAKQ 1187
Query: 866 SI----GGEAHYQCERGYNL--KGHQTRTCISKGQWNGTV--PVC 902
+ G + C+RGY L + H RT W+G + P C
Sbjct: 1188 KLYSRTGESVEFVCKRGYRLSSRSHTLRTTC----WDGKLEYPTC 1228
Score = 138 bits (334), Expect = 1e-31
Identities = 141/551 (25%), Positives = 216/551 (39%), Gaps = 56/551 (10%)
Query: 437 YSCRENFTLVGNPERTCGDEGIWDGEAPRCL--FDWCPDPPAVSNASV---TVNGHKAGS 491
+SC+ FT+VG C G+ + P C C PP + N +V T +
Sbjct: 595 FSCKPGFTIVGPNSVQCYHFGL-SPDLPICKEQVQSCGPPPELLNGNVKEKTKEEYGHSE 653
Query: 492 LASYTCENGHILSGSTSVTCTLGGAWSGVPPSC-KYVNCGT-PTIHKGSFVLINGTTTYG 549
+ Y C ++ G + C + G W+ +P + CG P + G L + YG
Sbjct: 654 VVEYYCNPRFLMKGPNKIQC-VDGEWTTLPVCIVEESTCGDIPELEHGWAQLSSPPYYYG 712
Query: 550 SIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSC----ELTSCPEPE--VPSGGYMEAFD 603
+F C + + G + C G W+ +P C +L C + +
Sbjct: 713 DSVEFNCSESFTMIGHRSITCIH-GVWT-QLPQCVAIDKLKKCKSSNLIILEEHLKNKKE 770
Query: 604 YYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYID---CGKLPTLPYGTMELL 660
+ +S I + C I + VC +G W + C C P +P
Sbjct: 771 FDHNSNIRYRCRGKEGWI---HTVCI-NGRWDPEV-NCSMAQIQLCPPPPQIPNSHNMTT 825
Query: 661 NGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRC-EEIRCSDPIVAEKSIVSV 719
G + C NY + TC ++ +W S P C E+I CS P E
Sbjct: 826 TLNYRDGEKVSVLCQENYLIQEGEEITC-KDGRWQ-SIPLCVEKIPCSQPPQIE------ 877
Query: 720 TGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPT 779
H I +S R +Y G + Y CE G+++ E+ +TC G+WS + P
Sbjct: 878 --------HGTINSS--RSSQESYAHGTKLSYTCEGGFRISEENETTCY-MGKWS-SPPQ 925
Query: 780 CQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPI 839
C+ + C +P I +G V S++ YG Y+C E + ++G C WS PP
Sbjct: 926 CEGLPCKSPPEISHGVVAHMSDSYQYGEEVTYKCFEGFGIDGPAIAKCL-GEKWS-HPPS 983
Query: 840 CKEITCPD-PSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGT 898
C + C PS + G G + Y C Y + G TCI+ +W G
Sbjct: 984 CIKTDCLSLPSFENAIPMG--EKKDVYKAGEQVTYTCATYYKMDGASNVTCIN-SRWTGR 1040
Query: 899 VPVCIPIDCRSPGNIENGKIVISNGSTL-FGSSVEYYCLSQYQRVGPFLRKCLDDGRWSG 957
P C C +P ++N IV S G V Y C S Y+ G CL +G W+
Sbjct: 1041 -PTCRDTSCVNPPTVQNAYIVSRQMSKYPSGERVRYQCRSPYEMFGDEEVMCL-NGNWT- 1097
Query: 958 EEPSCELATNE 968
E P C+ +T +
Sbjct: 1098 EPPQCKDSTGK 1108
Score = 135 bits (326), Expect = 9e-31
Identities = 154/621 (24%), Positives = 251/621 (40%), Gaps = 67/621 (10%)
Query: 367 NDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCK--YVNCGGLTPIEDGDVA- 423
+ Y VG + + C G ++G S C G S P CK +CG + +G+V
Sbjct: 585 DQYKVGEVLKFSCKPGFTIVGPNSVQCYHFGL-SPDLPICKEQVQSCGPPPELLNGNVKE 643
Query: 424 LIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFD--WCPDPPAVSN-- 479
H Y C F + G + C D G W P C+ + C D P + +
Sbjct: 644 KTKEEYGHSEVVEYYCNPRFLMKGPNKIQCVD-GEWT-TLPVCIVEESTCGDIPELEHGW 701
Query: 480 ASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSC---KYVNCGTPTIHK 536
A ++ + G + C + G S+TC + G W+ +P K C + +
Sbjct: 702 AQLSSPPYYYGDSVEFNCSESFTMIGHRSITC-IHGVWTQLPQCVAIDKLKKCKSSNLII 760
Query: 537 GSFVLINGTT-TYGSIAQFTCE-PDYWLNGAEELVCNRDGKWSYDIPSCELTS---CPEP 591
L N + S ++ C + W++ VC +G+W ++ +C + CP P
Sbjct: 761 LEEHLKNKKEFDHNSNIRYRCRGKEGWIH----TVCI-NGRWDPEV-NCSMAQIQLCPPP 814
Query: 592 -EVPSGGYMEA-FDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKL 649
++P+ M +Y ++ C+ + LI E + +DG W E I C +
Sbjct: 815 PQIPNSHNMTTTLNYRDGEKVSVLCQENY-LIQEGEEITCKDGRWQSIPLCVEKIPCSQP 873
Query: 650 PTLPYGTMELLNGTTHL---GSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRC 706
P + +GT+ + G+ + Y+C +R+ TC +WS S P+CE + C
Sbjct: 874 PQIEHGTINSSRSSQESYAHGTKLSYTCEGGFRISEENETTCYMG-KWS-SPPQCEGLPC 931
Query: 707 SDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLST 766
P + SHG + SD+ Y+ G V Y+C +G+ + G +++
Sbjct: 932 KSP------------PEISHG-VVAHMSDS------YQYGEEVTYKCFEGFGIDGPAIAK 972
Query: 767 CEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFY--GATAFYQCDENWELEGVIR 824
C +WS P+C DC + EN + + Y G Y C ++++G
Sbjct: 973 CLGE-KWSHP-PSCIKTDCLSLPSFENA-IPMGEKKDVYKAGEQVTYTCATYYKMDGASN 1029
Query: 825 RMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGH 884
C N W+ P C++ +C +P ++ + S G YQC Y + G
Sbjct: 1030 VTCI-NSRWTGRPT-CRDTSCVNPPT-VQNAYIVSRQMSKYPSGERVRYQCRSPYEMFGD 1086
Query: 885 QTRTCISKGQWNGTVPVCIPID--CRSPGNIENGKIVISNGSTLF-GSSVEYYCLSQYQR 941
+ C++ G W P C C P I+NG I S SSVEY C + YQ
Sbjct: 1087 EEVMCLN-GNWTEP-PQCKDSTGKCGPPPPIDNGDITSFPLSVYAPASSVEYQCQNLYQL 1144
Query: 942 VGPFLRKCLDDGRWSGEEPSC 962
G C +G+WS E P C
Sbjct: 1145 EGNKRITC-RNGQWS-EPPKC 1163
Score = 126 bits (305), Expect = 3e-28
Identities = 158/650 (24%), Positives = 243/650 (37%), Gaps = 78/650 (12%)
Query: 346 CQYLPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPP- 404
C LPP + ++L + Y G++ +YKC G+ LG+ C+K G W P
Sbjct: 21 CNELPPRRNT--EILTGSWSDQTYPEGTQAIYKCRPGYRSLGNVIMVCRK-GEWVALNPL 77
Query: 405 -SCKYVNCG--GLTPIEDGDVALI-DNRTTHGARALYSCRENFTLVGNPE-RTCGDEGIW 459
C+ CG G TP G L N +G +A+Y+C E + L+G R C +G W
Sbjct: 78 RKCQKRPCGHPGDTPF--GTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYRECDTDG-W 134
Query: 460 DGEAPRCLFDWCPDPPAVSNASVTVNG------HKAGSLASYTCENGHILSGSTSVTCTL 513
+ P C C A N + + + G + C +G+ + G + C+
Sbjct: 135 TNDIPICEVVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCSD 194
Query: 514 GGAWSGVPPSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRD 573
G WS P C ++C +P + GS + Q+ C Y + + VC
Sbjct: 195 DGFWSKEKPKCVEISCKSPDVINGSPISQKIIYKENERFQYKCNMGYEYSERGDAVCTES 254
Query: 574 GKWSYDIPSCELTSCPEPEVPSGGYME-AFDYYVHSTINFHCEAGHKLIGEPNLV-CQQD 631
G W +PSCE SC P +P+G Y + I + C G N C
Sbjct: 255 G-WR-PLPSCEEKSCDNPYIPNGDYSPLRIKHRTGDEITYQCRNGFYPATRGNTAKCTST 312
Query: 632 GEWSGDSPTCEYIDCGKLPTLPYG-----TMELLNGTTHLGSVIQYSCTTNYRLVGPV-- 684
G W +P C C P + +G M +G Y C ++
Sbjct: 313 G-WI-PAPRCTLKPC-DYPDIKHGGLYHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYW 369
Query: 685 -RRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTY 743
CT++ WS + P C +C P + G +++HG ++
Sbjct: 370 DHIHCTQD-GWSPAVP-CLR-KCYFPYLE-------NGYNQNHGRKFVQ----------- 408
Query: 744 RIGALVKYRCEKGYKV-IGESLSTCEDNGQWSGTTPTCQYVDCGNPG-RIENGKVTLPSN 801
G + C GY + ++ TC +NG WS T + C IENG ++
Sbjct: 409 --GKSIDVACHPGYALPKAQTTVTCMENG-WSPTPRCIRVKTCSKSSIDIENGFISESQY 465
Query: 802 ATFYGATAFYQCDENW-----ELEGVIRRMCQENGTWSLEPPICKEITCP-DPSAQIKAG 855
A YQC + E G I C ++G WS +P K P +A+ K
Sbjct: 466 TYALKEKAKYQCKLGYVTADGETSGSI--TCGKDG-WSAQPTCIKSCDIPVFMNARTKND 522
Query: 856 SGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNG--TVPVCIPIDCRSPGNI 913
+ TL Y+C GY T I G +NG +P+C +C P
Sbjct: 523 FTWFKLNDTLD------YECHDGYESNTGSTTGSIVCG-YNGWSDLPICYERECELPKID 575
Query: 914 ENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
+ G +++ C + VGP +C G S + P C+
Sbjct: 576 VHLVPDRKKDQYKVGEVLKFSCKPGFTIVGPNSVQCYHFG-LSPDLPICK 624
Score = 120 bits (290), Expect = 2e-26
Identities = 117/468 (25%), Positives = 193/468 (41%), Gaps = 55/468 (11%)
Query: 332 WN-DVGCNLDYLHWICQYLPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKS 390
W+ +V C++ + Q PP P+ TT L +Y G ++ C E +++ +
Sbjct: 797 WDPEVNCSMAQI----QLCPPPPQIPNSHNMTTTL--NYRDGEKVSVLCQENYLIQEGEE 850
Query: 391 RHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDV---ALIDNRTTHGARALYSCRENFTLVG 447
CK DG W P + + C IE G + HG + Y+C F +
Sbjct: 851 ITCK-DGRWQSIPLCVEKIPCSQPPQIEHGTINSSRSSQESYAHGTKLSYTCEGGFRISE 909
Query: 448 NPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVT--VNGHKAGSLASYTCENGHILSG 505
E TC G W P+C C PP +S+ V + ++ G +Y C G + G
Sbjct: 910 ENETTCY-MGKWSSP-PQCEGLPCKSPPEISHGVVAHMSDSYQYGEEVTYKCFEGFGIDG 967
Query: 506 STSVTCTLGGAWSGVPPSCKYVNCGTPTIHKGSFVLINGTTTY--GSIAQFTCEPDYWLN 563
C LG WS PPSC +C + + + + Y G +TC Y ++
Sbjct: 968 PAIAKC-LGEKWSH-PPSCIKTDCLSLPSFENAIPMGEKKDVYKAGEQVTYTCATYYKMD 1025
Query: 564 GAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYM---EAFDYYVHSTINFHCEAGHKL 620
GA + C + +W+ P+C TSC P Y+ + Y + + C + +++
Sbjct: 1026 GASNVTCI-NSRWT-GRPTCRDTSCVNPPTVQNAYIVSRQMSKYPSGERVRYQCRSPYEM 1083
Query: 621 IGEPNLVCQQDGEWSGDSPTCEYID--CGKLPTLPYGTMELLNGTTHL-GSVIQYSCTTN 677
G+ ++C +G W+ + P C+ CG P + G + + + S ++Y C
Sbjct: 1084 FGDEEVMCL-NGNWT-EPPQCKDSTGKCGPPPPIDNGDITSFPLSVYAPASSVEYQCQNL 1141
Query: 678 YRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNR 737
Y+L G R TC QWS E +C P V + I+ ++ L T+ +
Sbjct: 1142 YQLEGNKRITC-RNGQWS------EPPKCLHPCVISREIM------ENYNIALRWTAKQK 1188
Query: 738 DVGNTYRIGALVKYRCEKGYKVIGES---LSTCEDNGQWSGTT--PTC 780
T G V++ C++GY++ S +TC W G PTC
Sbjct: 1189 LYSRT---GESVEFVCKRGYRLSSRSHTLRTTC-----WDGKLEYPTC 1228
Score = 118 bits (284), Expect = 1e-25
Identities = 131/520 (25%), Positives = 194/520 (37%), Gaps = 51/520 (9%)
Query: 406 CKYVNCGGLTPIEDGDV---ALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGE 462
C +C L P + ++ + D G +A+Y CR + +GN C +G W
Sbjct: 16 CVAEDCNELPPRRNTEILTGSWSDQTYPEGTQAIYKCRPGYRSLGNVIMVCR-KGEWVAL 74
Query: 463 AP--RCLFDWCPDPPAVSNASVTVNGHKA---GSLASYTCENGHILSGSTSVT-CTLGGA 516
P +C C P + T+ G G A YTC G+ L G + C G
Sbjct: 75 NPLRKCQKRPCGHPGDTPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYRECDTDG- 133
Query: 517 WSGVPPSCKYVNCGTPTIHKGSFVLINGTTT-----YGSIAQFTCEPDYWLNGAEELVCN 571
W+ P C+ V C T + ++ + +G +F C Y + G EE+ C+
Sbjct: 134 WTNDIPICEVVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCS 193
Query: 572 RDGKWSYDIPSCELTSCPEPEVPSGG-YMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQ 630
DG WS + P C SC P+V +G + Y + + C G++ + VC +
Sbjct: 194 DDGFWSKEKPKCVEISCKSPDVINGSPISQKIIYKENERFQYKCNMGYEYSERGDAVCTE 253
Query: 631 DGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTN-YRLVGPVRRTCT 689
G W P+CE C P +P G L G I Y C Y CT
Sbjct: 254 SG-WR-PLPSCEEKSCDN-PYIPNGDYSPLRIKHRTGDEITYQCRNGFYPATRGNTAKCT 310
Query: 690 EEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALV 749
W +PRC C P D HG + + R +G
Sbjct: 311 ST-GWI-PAPRCTLKPCDYP-------------DIKHGG--LYHENMRRPYFPVAVGKYY 353
Query: 750 KYRCEKGYKVIGESL---STCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYG 806
Y C++ ++ S C +G WS P + C P +ENG G
Sbjct: 354 SYYCDEHFETPSGSYWDHIHCTQDG-WSPAVPCLR--KCYFP-YLENGYNQNHGRKFVQG 409
Query: 807 ATAFYQCDENWEL-EGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTL 865
+ C + L + C ENG WS P + TC S I+ G + T
Sbjct: 410 KSIDVACHPGYALPKAQTTVTCMENG-WSPTPRCIRVKTCSKSSIDIENGF-ISESQYTY 467
Query: 866 SIGGEAHYQCERGYNLKGHQTRTCISKGQ--WNGTVPVCI 903
++ +A YQC+ GY +T I+ G+ W+ P CI
Sbjct: 468 ALKEKAKYQCKLGYVTADGETSGSITCGKDGWSAQ-PTCI 506
Score = 113 bits (273), Expect = 2e-24
Identities = 156/645 (24%), Positives = 247/645 (38%), Gaps = 70/645 (10%)
Query: 345 ICQYLPPTCGSPDKLLNTTILGN-DYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAP 403
+ + LP T K++++ + + +Y G + + C G+ + GD+ HC DGFWS
Sbjct: 143 VVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCSDDGFWSKEK 202
Query: 404 PSCKYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEA 463
P C ++C I ++ R Y C + + C + G W
Sbjct: 203 PKCVEISCKSPDVINGSPISQ-KIIYKENERFQYKCNMGYEYSERGDAVCTESG-W-RPL 259
Query: 464 PRCLFDWCPDPPAVSNA--SVTVNGHKAGSLASYTCENG-HILSGSTSVTCTLGGAWSGV 520
P C C D P + N S H+ G +Y C NG + + + CT G W +
Sbjct: 260 PSCEEKSC-DNPYIPNGDYSPLRIKHRTGDEITYQCRNGFYPATRGNTAKCTSTG-W--I 315
Query: 521 P-PSCKYVNCGTPTIHKGSFVLINGTTTY-----GSIAQFTCEPDYWL-NGA--EELVCN 571
P P C C P I G N Y G + C+ + +G+ + + C
Sbjct: 316 PAPRCTLKPCDYPDIKHGGLYHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDHIHCT 375
Query: 572 RDGKWSYDIPSCELTSCPEPEVPSGGYMEAFDYYVH-STINFHCEAGHKL-IGEPNLVCQ 629
+DG WS +P C L C P + +G +V +I+ C G+ L + + C
Sbjct: 376 QDG-WSPAVP-C-LRKCYFPYLENGYNQNHGRKFVQGKSIDVACHPGYALPKAQTTVTCM 432
Query: 630 QDGEWSGDSPTCEYI-DCGKLP-TLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRR- 686
++G WS +P C + C K + G + T L +Y C Y
Sbjct: 433 ENG-WS-PTPRCIRVKTCSKSSIDIENGFISESQYTYALKEKAKYQCKLGYVTADGETSG 490
Query: 687 --TCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYR 744
TC ++ WS + P C + C P+ + T ND T + +D D
Sbjct: 491 SITCGKD-GWS-AQPTCIK-SCDIPVFMN----ARTKND----FTWFKLNDTLD------ 533
Query: 745 IGALVKYRCEKGYKVIGESLS---TCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSN 801
Y C GY+ S + C NG WS P C +C P +I+ V
Sbjct: 534 ------YECHDGYESNTGSTTGSIVCGYNG-WS-DLPICYERECELP-KIDVHLVPDRKK 584
Query: 802 ATF-YGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKE-ITCPDPSAQIKAGSGLL 859
+ G + C + + G C G S + PICKE + P ++ G+
Sbjct: 585 DQYKVGEVLKFSCKPGFTIVGPNSVQCYHFGL-SPDLPICKEQVQSCGPPPELLNGNVKE 643
Query: 860 VVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPID--CRSPGNIENGK 917
Y C + +KG C+ G+W T+PVCI + C +E+G
Sbjct: 644 KTKEEYGHSEVVEYYCNPRFLMKGPNKIQCVD-GEWT-TLPVCIVEESTCGDIPELEHGW 701
Query: 918 IVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
+S+ +G SVE+ C + +G C+ G W+ + P C
Sbjct: 702 AQLSSPPYYYGDSVEFNCSESFTMIGHRSITCI-HGVWT-QLPQC 744
Score = 111 bits (266), Expect = 2e-23
Identities = 158/643 (24%), Positives = 245/643 (38%), Gaps = 74/643 (11%)
Query: 352 TCGSPDKLLNTTILGND-YDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVN 410
+C SPD + + I Y R YKC G+ C + G W P SC+ +
Sbjct: 209 SCKSPDVINGSPISQKIIYKENERFQYKCNMGYEYSERGDAVCTESG-WRPLP-SCEEKS 266
Query: 411 CGGLTPIEDGDVALIDNRTTHGARALYSCRENF--TLVGNPERTCGDEGIWDGEAPRCLF 468
C I +GD + + + G Y CR F GN + C G W APRC
Sbjct: 267 CDN-PYIPNGDYSPLRIKHRTGDEITYQCRNGFYPATRGNTAK-CTSTG-WI-PAPRCTL 322
Query: 469 DWCPDPPAVSNASVTVNGHK------AGSLASYTC-ENGHILSGS--TSVTCTLGGAWSG 519
C P N + G SY C E+ SGS + CT G WS
Sbjct: 323 KPCDYPDIKHGGLYHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDHIHCTQDG-WSP 381
Query: 520 VPPSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYD 579
P + C P + G G C P Y L A+ V + WS
Sbjct: 382 AVPCLR--KCYFPYLENGYNQNHGRKFVQGKSIDVACHPGYALPKAQTTVTCMENGWS-P 438
Query: 580 IPSC-ELTSCPEP--EVPSGGYMEA-FDYYVHSTINFHCEAGHKLI-GEPN--LVCQQDG 632
P C + +C + ++ +G E+ + Y + + C+ G+ GE + + C +DG
Sbjct: 439 TPRCIRVKTCSKSSIDIENGFISESQYTYALKEKAKYQCKLGYVTADGETSGSITCGKDG 498
Query: 633 EWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRL-VGPVRRTCTEE 691
WS PTC I +P + L + Y C Y G +
Sbjct: 499 -WSAQ-PTC--IKSCDIPVFMNARTKNDFTWFKLNDTLDYECHDGYESNTGSTTGSIVCG 554
Query: 692 FQ-WSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVK 750
+ WSD P C E C P + + +V D+ Y++G ++K
Sbjct: 555 YNGWSDL-PICYERECELPKI-DVHLVPDRKKDQ------------------YKVGEVLK 594
Query: 751 YRCEKGYKVIGESLSTCEDNGQWSGTTPTC--QYVDCGNPGRIENGKVTLPSNATF-YGA 807
+ C+ G+ ++G + C G S P C Q CG P + NG V + + +
Sbjct: 595 FSCKPGFTIVGPNSVQCYHFG-LSPDLPICKEQVQSCGPPPELLNGNVKEKTKEEYGHSE 653
Query: 808 TAFYQCDENWELEGVIRRMCQENGTWSLEPP-ICKEITCPDPSAQIKAGSGLLVVTSTLS 866
Y C+ + ++G + C + G W+ P I +E TC D +++ G L +
Sbjct: 654 VVEYYCNPRFLMKGPNKIQCVD-GEWTTLPVCIVEESTCGD-IPELEHGWAQL-SSPPYY 710
Query: 867 IGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPID----CRSPGNIENGKIVISN 922
G + C + + GH++ TCI G W +P C+ ID C+S I + + +
Sbjct: 711 YGDSVEFNCSESFTMIGHRSITCI-HGVWT-QLPQCVAIDKLKKCKSSNLIILEEHLKNK 768
Query: 923 GSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCELA 965
S++ Y C + G C+ +GRW E +C +A
Sbjct: 769 KEFDHNSNIRYRCRG---KEGWIHTVCI-NGRWD-PEVNCSMA 806
Score = 94.3 bits (224), Expect = 2e-18
Identities = 86/337 (25%), Positives = 126/337 (37%), Gaps = 43/337 (12%)
Query: 641 CEYIDCGKLPTLPYGTMELLNG-----TTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWS 695
C DC +LP P E+L G T G+ Y C YR +G V C + +W
Sbjct: 16 CVAEDCNELP--PRRNTEILTGSWSDQTYPEGTQAIYKCRPGYRSLGNVIMVCRKG-EWV 72
Query: 696 DSSP--RCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRC 753
+P +C++ C P ++TG GN + G Y C
Sbjct: 73 ALNPLRKCQKRPCGHPGDTPFGTFTLTG------------------GNVFEYGVKAVYTC 114
Query: 754 EKGYKVIGE-SLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTL----PSNATFYGAT 808
+GY+++GE + C+ +G W+ P C+ V C ENGK+ P +G
Sbjct: 115 NEGYQLLGEINYRECDTDG-WTNDIPICEVVKCLPVTAPENGKIVSSAMEPDREYHFGQA 173
Query: 809 AFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIG 868
+ C+ +++EG C ++G WS E P C EI+C P + ++
Sbjct: 174 VRFVCNSGYKIEGDEEMHCSDDGFWSKEKPKCVEISCKSPDVINGSPISQKIIYKE---N 230
Query: 869 GEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFG 928
Y+C GY C G W +P C C +P I NG G
Sbjct: 231 ERFQYKCNMGYEYSERGDAVCTESG-WR-PLPSCEEKSCDNP-YIPNGDYSPLRIKHRTG 287
Query: 929 SSVEYYCLSQ-YQRVGPFLRKCLDDGRWSGEEPSCEL 964
+ Y C + Y KC G W P C L
Sbjct: 288 DEITYQCRNGFYPATRGNTAKCTSTG-WI-PAPRCTL 322
Score = 45.6 bits (103), Expect = 0.001
Identities = 23/58 (39%), Positives = 28/58 (48%), Gaps = 2/58 (3%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFG-ARQRECTLRGDWTLEPPFC 58
CGHP P ++ G AVY C+EGY+L G REC G WT + P C
Sbjct: 85 CGHPGDTPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYRECDTDG-WTNDIPIC 141
Score = 37.9 bits (84), Expect = 0.20
Identities = 20/57 (35%), Positives = 27/57 (47%), Gaps = 2/57 (3%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C +P NA + +G Y+C YE+FG + C L G+WT EPP C
Sbjct: 1048 CVNPPTVQNAYIVSRQMSKYPSGERVRYQCRSPYEMFGDEEVMC-LNGNWT-EPPQC 1102
>AL021940-2|CAI19358.1| 547|Homo sapiens selectin E (endothelial
adhesion molecule 1) protein.
Length = 547
Score = 153 bits (371), Expect = 3e-36
Identities = 99/381 (25%), Positives = 163/381 (42%), Gaps = 33/381 (8%)
Query: 499 NGHILSGSTSVTCTLGGAWSGVPPSCKYVNC-GTPTIHKGSFVLIN--GTTTYGSIAQFT 555
+G + + TC +SG+ + VNC + GS V + G +Y S +
Sbjct: 151 HGECVETINNYTCKCDPGFSGLKCE-QIVNCTALESPEHGSLVCSHPLGNFSYNSSCSIS 209
Query: 556 CEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFD----YYVHSTIN 611
C+ Y + E + C G+WS IP+C + C P+ G++E F + ++T
Sbjct: 210 CDRGYLPSSMETMQCMSSGEWSAPIPACNVVECDAVTNPANGFVECFQNPGSFPWNTTCT 269
Query: 612 FHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLN---GTTHLGS 668
F CE G +L+G +L C G W + PTC+ + C + G++ + G S
Sbjct: 270 FDCEEGFELMGAQSLQCTSSGNWDNEKPTCKAVTCRAVRQPQNGSVRCSHSPAGEFTFKS 329
Query: 669 VIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGH 728
++C + L GP + CT + QW+ P CE +C+ +++ +R + +
Sbjct: 330 SCNFTCEEGFMLQGPAQVECTTQGQWTQQIPVCEAFQCT----------ALSNPERGYMN 379
Query: 729 TLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNP 788
L S ++R G+ ++ CE+G+ + G C G+W PTC+ V C +
Sbjct: 380 CLPSAS------GSFRYGSSCEFSCEQGFVLKGSKRLQCGPTGEWDNEKPTCEVVKCSS- 432
Query: 789 GRIENGKVTLP-SNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICK---EIT 844
GK+ + S +G + C E W L G R C G WS P C+ E
Sbjct: 433 -LAVPGKINMSCSGEPVFGTVCKFACPEGWTLNGSAARTCGATGHWSGLLPTCEAPTESN 491
Query: 845 CPDPSAQIKAGSGLLVVTSTL 865
P + AG LL + L
Sbjct: 492 IPLVAGLSAAGLSLLTLAPFL 512
Score = 145 bits (352), Expect = 7e-34
Identities = 130/507 (25%), Positives = 188/507 (37%), Gaps = 56/507 (11%)
Query: 236 SFDEARKQCQSHGGDLIHGFQGATSSFLTQELERRKAQLKTQLVWIGAQKEPGLTSRTWQ 295
++DEA CQ L+ +L L WIG +K + W
Sbjct: 32 TYDEASAYCQQRYTHLVAIQNKEEIEYLNSILS-----YSPSYYWIGIRK----VNNVWV 82
Query: 296 WVDGE---LVSKPSWGKDQPNNYNGEQNCVVLDGGRG---WLWNDVGCNLDYLHWICQYL 349
WV + +W +PNN +++CV + R +WND C+ L +C
Sbjct: 83 WVGTQKPLTEEAKNWAPGEPNNRQKDEDCVEIYIKREKDVGMWNDERCSKKKLA-LCYTA 141
Query: 350 PPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYV 409
T NT+ G+ +C E + CK D +SG + V
Sbjct: 142 ACT--------NTSCSGHG---------ECVETI-----NNYTCKCDPGFSGLKCE-QIV 178
Query: 410 NCGGLTPIEDGDVALID--NRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL 467
NC L E G + ++ + SC + C G W P C
Sbjct: 179 NCTALESPEHGSLVCSHPLGNFSYNSSCSISCDRGYLPSSMETMQCMSSGEWSAPIPACN 238
Query: 468 FDWCPDPPAVSNASVTVNGHKAG----SLASYTCENGHILSGSTSVTCTLGGAWSGVPPS 523
C +N V + + ++ CE G L G+ S+ CT G W P+
Sbjct: 239 VVECDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGNWDNEKPT 298
Query: 524 CKYVNCGTPTIHKGSFVLIN----GTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYD 579
CK V C + V + G T+ S FTCE + L G ++ C G+W+
Sbjct: 299 CKAVTCRAVRQPQNGSVRCSHSPAGEFTFKSSCNFTCEEGFMLQGPAQVECTTQGQWTQQ 358
Query: 580 IPSCELTSCPEPEVPSGGYMEAF-----DYYVHSTINFHCEAGHKLIGEPNLVCQQDGEW 634
IP CE C P GYM + S+ F CE G L G L C GEW
Sbjct: 359 IPVCEAFQCTALSNPERGYMNCLPSASGSFRYGSSCEFSCEQGFVLKGSKRLQCGPTGEW 418
Query: 635 SGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQW 694
+ PTCE + C L +P +G G+V +++C + L G RTC W
Sbjct: 419 DNEKPTCEVVKCSSL-AVPGKINMSCSGEPVFGTVCKFACPEGWTLNGSAARTCGATGHW 477
Query: 695 SDSSPRCEEIRCSD-PIVAEKSIVSVT 720
S P CE S+ P+VA S ++
Sbjct: 478 SGLLPTCEAPTESNIPLVAGLSAAGLS 504
Score = 143 bits (347), Expect = 3e-33
Identities = 85/302 (28%), Positives = 126/302 (41%), Gaps = 31/302 (10%)
Query: 491 SLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTIHKGSFVLI---NGTTT 547
S S +C+ G++ S ++ C G WS P+C V C T FV G+
Sbjct: 204 SSCSISCDRGYLPSSMETMQCMSSGEWSAPIPACNVVECDAVTNPANGFVECFQNPGSFP 263
Query: 548 YGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGG-----YMEAF 602
+ + F CE + L GA+ L C G W + P+C+ +C P G + A
Sbjct: 264 WNTTCTFDCEEGFELMGAQSLQCTSSGNWDNEKPTCKAVTCRAVRQPQNGSVRCSHSPAG 323
Query: 603 DYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELL-- 660
++ S+ NF CE G L G + C G+W+ P CE C L G M L
Sbjct: 324 EFTFKSSCNFTCEEGFMLQGPAQVECTTQGQWTQQIPVCEAFQCTALSNPERGYMNCLPS 383
Query: 661 -NGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSV 719
+G+ GS ++SC + L G R C +W + P CE ++CS V K +S
Sbjct: 384 ASGSFRYGSSCEFSCEQGFVLKGSKRLQCGPTGEWDNEKPTCEVVKCSSLAVPGKINMSC 443
Query: 720 TGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPT 779
+G G + K+ C +G+ + G + TC G WSG PT
Sbjct: 444 SGEP--------------------VFGTVCKFACPEGWTLNGSAARTCGATGHWSGLLPT 483
Query: 780 CQ 781
C+
Sbjct: 484 CE 485
Score = 121 bits (291), Expect = 2e-26
Identities = 95/376 (25%), Positives = 147/376 (39%), Gaps = 32/376 (8%)
Query: 605 YVHSTINFHCEAGHKLIGEP--NLVCQQDGEWSGDSPTCEYI-DCGKLPTLPYGTMELLN 661
Y + N C +GH E N C+ D +SG CE I +C L + +G++ +
Sbjct: 139 YTAACTNTSC-SGHGECVETINNYTCKCDPGFSGLK--CEQIVNCTALESPEHGSLVCSH 195
Query: 662 --GTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSV 719
G S SC Y C +WS P C + C V
Sbjct: 196 PLGNFSYNSSCSISCDRGYLPSSMETMQCMSSGEWSAPIPACNVVECDAVTNPANGFVEC 255
Query: 720 TGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPT 779
N S T D CE+G++++G C +G W PT
Sbjct: 256 FQNPGSFPWNTTCTFD-----------------CEEGFELMGAQSLQCTSSGNWDNEKPT 298
Query: 780 CQYVDCGNPGRIENGKVTL---PSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLE 836
C+ V C + +NG V P+ + ++ + C+E + L+G + C G W+ +
Sbjct: 299 CKAVTCRAVRQPQNGSVRCSHSPAGEFTFKSSCNFTCEEGFMLQGPAQVECTTQGQWTQQ 358
Query: 837 PPICKEITCPDPSAQIKAGSGLLVVTS-TLSIGGEAHYQCERGYNLKGHQTRTCISKGQW 895
P+C+ C S + L S + G + CE+G+ LKG + C G+W
Sbjct: 359 IPVCEAFQCTALSNPERGYMNCLPSASGSFRYGSSCEFSCEQGFVLKGSKRLQCGPTGEW 418
Query: 896 NGTVPVCIPIDCRSPGNIENGKIVIS-NGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGR 954
+ P C + C S GKI +S +G +FG+ ++ C + G R C G
Sbjct: 419 DNEKPTCEVVKCSSLA--VPGKINMSCSGEPVFGTVCKFACPEGWTLNGSAARTCGATGH 476
Query: 955 WSGEEPSCELATNEAV 970
WSG P+CE T +
Sbjct: 477 WSGLLPTCEAPTESNI 492
Score = 46.4 bits (105), Expect = 6e-04
Identities = 26/73 (35%), Positives = 35/73 (47%), Gaps = 3/73 (4%)
Query: 2 CGHPAVPPNARVS-IPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCG- 59
C P N V N + T ++C+EG+EL GA+ +CT G+W E P C
Sbjct: 242 CDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGNWDNEKPTCKA 301
Query: 60 -TNVAFRKPANQS 71
T A R+P N S
Sbjct: 302 VTCRAVRQPQNGS 314
Score = 38.3 bits (85), Expect = 0.15
Identities = 14/30 (46%), Positives = 19/30 (63%)
Query: 29 YECDEGYELFGARQRECTLRGDWTLEPPFC 58
+ C+EG+ L G Q ECT +G WT + P C
Sbjct: 333 FTCEEGFMLQGPAQVECTTQGQWTQQIPVC 362
Score = 38.3 bits (85), Expect = 0.15
Identities = 20/58 (34%), Positives = 27/58 (46%), Gaps = 2/58 (3%)
Query: 1 RCGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
+C AVP +S E V GT+ + C EG+ L G+ R C G W+ P C
Sbjct: 429 KCSSLAVPGKINMSCSGEP--VFGTVCKFACPEGWTLNGSAARTCGATGHWSGLLPTC 484
Score = 33.5 bits (73), Expect = 4.2
Identities = 11/35 (31%), Positives = 21/35 (60%)
Query: 24 GTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
G+ + C++G+ L G+++ +C G+W E P C
Sbjct: 391 GSSCEFSCEQGFVLKGSKRLQCGPTGEWDNEKPTC 425
>AY114160-1|AAM47024.1| 388|Homo sapiens complement C4b binding
protein CR-1 like protein.
Length = 388
Score = 153 bits (370), Expect = 4e-36
Identities = 111/412 (26%), Positives = 172/412 (41%), Gaps = 46/412 (11%)
Query: 549 GSIAQFTCEPDYWLNGAE-ELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAF-DYYV 606
G+ + C P Y +G ++C ++ W+ C+ SC P P G D
Sbjct: 2 GTYLNYECRPGY--SGRPFSIICLKNSVWTSAKDKCKRKSCRNPPDPVNGMAHVIKDIQF 59
Query: 607 HSTINFHCEAGHKLIGEPNLVCQQDGE---WSGDSPTCEYIDCGKLPTLPYGTMELLNGT 663
S I + C G++LIG + C G W +P C+ I CG PT+ G ++
Sbjct: 60 RSQIKYSCPKGYRLIGSSSATCIISGNTVIWDNKTPVCDRIICGLPPTIANGDFTSISRE 119
Query: 664 T-HLGSVIQYSCTTNYR------LVGPVRRTCTEEFQ----WSDSSPRCE-EIRCSDPIV 711
H GSV+ Y C R LVG CT + WS +P+C +C+ P V
Sbjct: 120 YFHYGSVVTYHCNLGSRGKKVFELVGEPSIYCTSKDDQVGIWSGPAPQCIIPNKCTPPNV 179
Query: 712 AEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNG 771
+VS DNR + + + +V++RC+ G+ + G S C+
Sbjct: 180 ENGILVS----------------DNRSL---FSLNEVVEFRCQPGFGMKGPSHVKCQALN 220
Query: 772 QWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFY-GATAFYQCDENWELEGVIRRMCQEN 830
+W P+C V C P + + + T F G FY C+ ++L G C
Sbjct: 221 KWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGSTYLHCTPQ 279
Query: 831 GTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCI 890
G WS P C+ +C D Q+ G L + L +G + + C+ G+ LKG C+
Sbjct: 280 GDWSPAAPRCEVKSCDDFLGQLPNGHVLFPL--NLQLGAKVDFVCDEGFQLKGSSASYCV 337
Query: 891 SKGQ---WNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQY 939
G WN +VPVC C +P NG + + + GS + Y C + +
Sbjct: 338 LAGMESLWNSSVPVCERKSCETPPVPVNGMVHVITDIHV-GSRINYSCTTGF 388
Score = 147 bits (356), Expect = 2e-34
Identities = 102/347 (29%), Positives = 146/347 (42%), Gaps = 26/347 (7%)
Query: 356 PDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDG---FWSGAPPSCKYVNCG 412
PD + + D S+I Y CP+G+ L+G S C G W P C + CG
Sbjct: 44 PDPVNGMAHVIKDIQFRSQIKYSCPKGYRLIGSSSATCIISGNTVIWDNKTPVCDRIICG 103
Query: 413 GLTPIEDGDVALIDNRTTH-GARALYSC------RENFTLVGNPERTCGDE----GIWDG 461
I +GD I H G+ Y C ++ F LVG P C + GIW G
Sbjct: 104 LPPTIANGDFTSISREYFHYGSVVTYHCNLGSRGKKVFELVGEPSIYCTSKDDQVGIWSG 163
Query: 462 EAPRCLFDWCPDPPAVSNASVTVNGHKAGSL---ASYTCENGHILSGSTSVTCTLGGAWS 518
AP+C+ PP V N + + SL + C+ G + G + V C W
Sbjct: 164 PAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFGMKGPSHVKCQALNKWE 223
Query: 519 GVPPSCKYVNCGTP--TIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKW 576
PSC V C P +H + G ++CEP Y L G+ L C G W
Sbjct: 224 PELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGSTYLHCTPQGDW 282
Query: 577 SYDIPSCELTSCPE--PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGE- 633
S P CE+ SC + ++P+G + + + + ++F C+ G +L G C G
Sbjct: 283 SPAAPRCEVKSCDDFLGQLPNGHVLFPLNLQLGAKVDFVCDEGFQLKGSSASYCVLAGME 342
Query: 634 --WSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNY 678
W+ P CE C + P +P M + H+GS I YSCTT +
Sbjct: 343 SLWNSSVPVCERKSC-ETPPVPVNGMVHVITDIHVGSRINYSCTTGF 388
Score = 142 bits (343), Expect = 8e-33
Identities = 103/373 (27%), Positives = 155/373 (41%), Gaps = 27/373 (7%)
Query: 371 VGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRTT 430
+G+ + Y+C G+ S C K+ W+ A CK +C P +A +
Sbjct: 1 IGTYLNYECRPGYSGR-PFSIICLKNSVWTSAKDKCKRKSCRN-PPDPVNGMAHVIKDIQ 58
Query: 431 HGARALYSCRENFTLVGNPERTC---GDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGH 487
++ YSC + + L+G+ TC G+ IWD + P C C PP ++N T
Sbjct: 59 FRSQIKYSCPKGYRLIGSSSATCIISGNTVIWDNKTPVCDRIICGLPPTIANGDFTSISR 118
Query: 488 KA---GSLASYTCENGHI------LSGSTSVTCTLG----GAWSGVPPSCKYVN-CGTPT 533
+ GS+ +Y C G L G S+ CT G WSG P C N C P
Sbjct: 119 EYFHYGSVVTYHCNLGSRGKKVFELVGEPSIYCTSKDDQVGIWSGPAPQCIIPNKCTPPN 178
Query: 534 IHKGSFVLINGTT-TYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPE 592
+ G V N + + + +F C+P + + G + C KW ++PSC P P+
Sbjct: 179 VENGILVSDNRSLFSLNEVVEFRCQPGFGMKGPSHVKCQALNKWEPELPSCSRVCQPPPD 238
Query: 593 V--PSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGK-L 649
V + ++ + + CE G+ L G L C G+WS +P CE C L
Sbjct: 239 VLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGSTYLHCTPQGDWSPAAPRCEVKSCDDFL 298
Query: 650 PTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCT---EEFQWSDSSPRCEEIRC 706
LP G + L LG+ + + C ++L G C E W+ S P CE C
Sbjct: 299 GQLPNGHV-LFPLNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCERKSC 357
Query: 707 SDPIVAEKSIVSV 719
P V +V V
Sbjct: 358 ETPPVPVNGMVHV 370
Score = 117 bits (281), Expect = 3e-25
Identities = 91/368 (24%), Positives = 143/368 (38%), Gaps = 33/368 (8%)
Query: 610 INFHCEAGHKLIGEP-NLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGS 668
+N+ C G+ G P +++C ++ W+ C+ C P P M + S
Sbjct: 5 LNYECRPGYS--GRPFSIICLKNSVWTSAKDKCKRKSCRNPPD-PVNGMAHVIKDIQFRS 61
Query: 669 VIQYSCTTNYRLVGPVRRTCT---EEFQWSDSSPRCEEIRCS-DPIVAEKSIVSVTGNDR 724
I+YSC YRL+G TC W + +P C+ I C P +A S++
Sbjct: 62 QIKYSCPKGYRLIGSSSATCIISGNTVIWDNKTPVCDRIICGLPPTIANGDFTSISREYF 121
Query: 725 SHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDN----GQWSGTTPTC 780
+G + TY + R +K ++++GE C G WSG P C
Sbjct: 122 HYGSVV-----------TYHCN--LGSRGKKVFELVGEPSIYCTSKDDQVGIWSGPAPQC 168
Query: 781 QYVDCGNPGRIENGKVTLPSNATF-YGATAFYQCDENWELEGVIRRMCQENGTWSLEPPI 839
+ P +ENG + + + F ++C + ++G CQ W E P
Sbjct: 169 IIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFGMKGPSHVKCQALNKWEPELPS 228
Query: 840 CKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTV 899
C + P P + S G E Y CE GY+L+G C +G W+
Sbjct: 229 CSRVCQPPPD--VLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGSTYLHCTPQGDWSPAA 286
Query: 900 PVCIPIDCRS-PGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGR---W 955
P C C G + NG ++ L G+ V++ C +Q G C+ G W
Sbjct: 287 PRCEVKSCDDFLGQLPNGHVLFPLNLQL-GAKVDFVCDEGFQLKGSSASYCVLAGMESLW 345
Query: 956 SGEEPSCE 963
+ P CE
Sbjct: 346 NSSVPVCE 353
Score = 95.5 bits (227), Expect = 9e-19
Identities = 79/316 (25%), Positives = 124/316 (39%), Gaps = 42/316 (13%)
Query: 666 LGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRS 725
+G+ + Y C Y P C + W+ + +C+ C +P + V
Sbjct: 1 IGTYLNYECRPGYS-GRPFSIICLKNSVWTSAKDKCKRKSCRNPPDPVNGMAHVI----- 54
Query: 726 HGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTCQY 782
+D+ + + +KY C KGY++IG S +TC +G W TP C
Sbjct: 55 -----------KDI----QFRSQIKYSCPKGYRLIGSSSATCIISGNTVIWDNKTPVCDR 99
Query: 783 VDCGNPGRIENGKVTLPSNATF-YGATAFYQCD------ENWELEGVIRRMC----QENG 831
+ CG P I NG T S F YG+ Y C+ + +EL G C + G
Sbjct: 100 IICGLPPTIANGDFTSISREYFHYGSVVTYHCNLGSRGKKVFELVGEPSIYCTSKDDQVG 159
Query: 832 TWSLEPPICKEITCPDPSAQIKAGSGLLVV--TSTLSIGGEAHYQCERGYNLKGHQTRTC 889
WS P C P+ +G+LV S S+ ++C+ G+ +KG C
Sbjct: 160 IWSGPAPQC---IIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFGMKGPSHVKC 216
Query: 890 ISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLF-GSSVEYYCLSQYQRVGPFLRK 948
+ +W +P C + C+ P ++ + + + G V Y C Y G
Sbjct: 217 QALNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGSTYLH 275
Query: 949 CLDDGRWSGEEPSCEL 964
C G WS P CE+
Sbjct: 276 CTPQGDWSPAAPRCEV 291
Score = 39.9 bits (89), Expect = 0.049
Identities = 18/57 (31%), Positives = 28/57 (49%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C P +A + +++N G Y C+ GY+L G+ CT +GDW+ P C
Sbjct: 233 CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGSTYLHCTPQGDWSPAAPRC 289
>Z99572-6|CAI23062.1| 645|Homo sapiens selectin P (granule membrane
protein 140kDa, antigen CD62) protein.
Length = 645
Score = 152 bits (368), Expect = 8e-36
Identities = 143/581 (24%), Positives = 232/581 (39%), Gaps = 89/581 (15%)
Query: 236 SFDEARKQCQSHGGDLIHGFQGATSSFLTQELERRKAQLKTQLVWIGAQKEPGLTSRTWQ 295
S++ +RK CQ+ DL+ +L + L + WIG +K ++TW
Sbjct: 51 SWNISRKYCQNRYTDLVAIQNKNEIDYLNKVLP-----YYSSYYWIGIRKN----NKTWT 101
Query: 296 WVDGELV---SKPSWGKDQPNNYNGEQNCV---VLDGGRGWLWNDVGCNLDYLHWICQYL 349
WV + +W ++PNN ++CV + WND C L H +C
Sbjct: 102 WVGTKKALTNEAENWADNEPNNKRNNEDCVEIYIKSPSAPGKWNDEHC-LKKKHALCY-- 158
Query: 350 PPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYV 409
T D ++ + G +C E +G+ + C GF+ P C+YV
Sbjct: 159 --TASCQD--MSCSKQG-----------ECLE---TIGNYTCSCYP-GFYG---PECEYV 196
Query: 410 N-CGGLTPIEDGDVALID--NRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRC 466
CG L + + + ++ + C + + + G + C GIW + P+C
Sbjct: 197 RECGELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQC 256
Query: 467 LFDWCPDPPAVSNASVT-VNGHKA---GSLASYTCENGHILSGSTSVTCTLGGAWSGVPP 522
L CP ++T ++ KA S S++CE G L G V CT G W+ P
Sbjct: 257 LAAQCPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASGVWTAPAP 316
Query: 523 SCKYVNCGT--PTIHKGSFVLINGTTT--YGSIAQFTCEPDYWLNGAEELVCNRDGKWSY 578
CK ++C +H GS Y + F C + L GA+ + C+ G+W+
Sbjct: 317 VCKAISCEPLESPVH-GSMDCSPSLRAFQYDTNCSFRCAEGFMLRGADIVRCDNLGQWTA 375
Query: 579 DIPSCELTSCPEPEVPSGGYME------AFDYYVHSTINFHCEAGHKLIGEPNLVCQQDG 632
P C+ C + VP+ + AF Y S +F C G L+G L C G
Sbjct: 376 PAPVCQALQCQDLPVPNEARVNCSHPFGAFRY--QSVCSFTCNEGLLLVGASVLQCLATG 433
Query: 633 EWSGDSPTCEY----------IDCGKLPTLPYGTMELLN--GTTHLGSVIQYSCTTNYRL 680
W+ P C+ + C L T GTM + GT + + C + L
Sbjct: 434 NWNSVPPECQGKSIASLPTPGVQCPALTTPGQGTMYCRHHPGTFGFNTTCYFGCNAGFTL 493
Query: 681 VGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVG 740
+G +C QW+ +P C ++CS+ + K I N +
Sbjct: 494 IGDSTLSCRPSGQWTAVTPACRAVKCSE-LHVNKPIAMNCSN----------------LW 536
Query: 741 NTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQ 781
+ G++ + C +G + G + + C++NG WS T PTCQ
Sbjct: 537 GNFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTCQ 577
Score = 139 bits (337), Expect = 4e-32
Identities = 105/404 (25%), Positives = 159/404 (39%), Gaps = 38/404 (9%)
Query: 581 PSCE-LTSCPEPEVPSGGYMEAF----DYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWS 635
P CE + C E E+P M ++ +S +FHC G+++ G L C G W+
Sbjct: 191 PECEYVRECGELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPSKLECLASGIWT 250
Query: 636 GDSPTCEYIDCGKLPTLPYGTMELLNGTTHLG--SVIQYSCTTNYRLVGPVRRTCTEEFQ 693
P C C L G M L+ S +SC + LVGP CT
Sbjct: 251 NKPPQCLAAQCPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASGV 310
Query: 694 WSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRC 753
W+ +P C+ I C +P+ E + HG + D ++ +RC
Sbjct: 311 WTAPAPVCKAISC-EPL--ESPV---------HG-----SMDCSPSLRAFQYDTNCSFRC 353
Query: 754 EKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTL--PSNATFYGATAFY 811
+G+ + G + C++ GQW+ P CQ + C + +V P A Y + +
Sbjct: 354 AEGFMLRGADIVRCDNLGQWTAPAPVCQALQCQDLPVPNEARVNCSHPFGAFRYQSVCSF 413
Query: 812 QCDENWELEGVIRRMCQENGTWSLEPPIC--KEI-TCPDPSAQIKA----GSGLLVV--- 861
C+E L G C G W+ PP C K I + P P Q A G G +
Sbjct: 414 TCNEGLLLVGASVLQCLATGNWNSVPPECQGKSIASLPTPGVQCPALTTPGQGTMYCRHH 473
Query: 862 TSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVIS 921
T ++ C G+ L G T +C GQW P C + C + + S
Sbjct: 474 PGTFGFNTTCYFGCNAGFTLIGDSTLSCRPSGQWTAVTPACRAVKCSELHVNKPIAMNCS 533
Query: 922 N--GSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
N G+ +GS ++CL G C ++G WS P+C+
Sbjct: 534 NLWGNFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTCQ 577
Score = 54.8 bits (126), Expect = 2e-06
Identities = 27/109 (24%), Positives = 45/109 (41%), Gaps = 2/109 (1%)
Query: 866 SIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGST 925
S + + C GY + G C++ G W P C+ C E G + + +
Sbjct: 220 SFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQCLAAQCPPLKIPERGNMTCLHSAK 279
Query: 926 LF--GSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCELATNEAVDS 972
F SS + C + VGP + +C G W+ P C+ + E ++S
Sbjct: 280 AFQHQSSCSFSCEEGFALVGPEVVQCTASGVWTAPAPVCKAISCEPLES 328
Score = 35.9 bits (79), Expect = 0.79
Identities = 16/58 (27%), Positives = 28/58 (48%), Gaps = 1/58 (1%)
Query: 2 CGHPAVPPNARVSIPNE-ENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
CG +P + ++ + N + + C +GY++ G + EC G WT +PP C
Sbjct: 199 CGELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQC 256
Score = 35.5 bits (78), Expect = 1.0
Identities = 20/65 (30%), Positives = 31/65 (47%), Gaps = 2/65 (3%)
Query: 1 RCGHPAVPPNARVSIPNEENIVA-GTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC- 58
+C VP ARV+ + ++ + C+EG L GA +C G+W PP C
Sbjct: 384 QCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPECQ 443
Query: 59 GTNVA 63
G ++A
Sbjct: 444 GKSIA 448
Score = 34.3 bits (75), Expect = 2.4
Identities = 12/30 (40%), Positives = 16/30 (53%)
Query: 29 YECDEGYELFGARQRECTLRGDWTLEPPFC 58
+ C+EG+ L G +CT G WT P C
Sbjct: 289 FSCEEGFALVGPEVVQCTASGVWTAPAPVC 318
Score = 32.3 bits (70), Expect = 9.7
Identities = 20/62 (32%), Positives = 27/62 (43%), Gaps = 3/62 (4%)
Query: 20 NIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTNVAFRKPANQSTTVRGGAA 79
N G+I + C EG L G+ Q C G W+ P C A ++ T GGA
Sbjct: 538 NFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTC---QAGPLTIQEALTYFGGAV 594
Query: 80 AN 81
A+
Sbjct: 595 AS 596
>Z99572-1|CAI23060.1| 646|Homo sapiens selectin P (granule membrane
protein 140kDa, antigen CD62) protein.
Length = 646
Score = 152 bits (368), Expect = 8e-36
Identities = 143/581 (24%), Positives = 232/581 (39%), Gaps = 89/581 (15%)
Query: 236 SFDEARKQCQSHGGDLIHGFQGATSSFLTQELERRKAQLKTQLVWIGAQKEPGLTSRTWQ 295
S++ +RK CQ+ DL+ +L + L + WIG +K ++TW
Sbjct: 52 SWNISRKYCQNRYTDLVAIQNKNEIDYLNKVLP-----YYSSYYWIGIRKN----NKTWT 102
Query: 296 WVDGELV---SKPSWGKDQPNNYNGEQNCV---VLDGGRGWLWNDVGCNLDYLHWICQYL 349
WV + +W ++PNN ++CV + WND C L H +C
Sbjct: 103 WVGTKKALTNEAENWADNEPNNKRNNEDCVEIYIKSPSAPGKWNDEHC-LKKKHALCY-- 159
Query: 350 PPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYV 409
T D ++ + G +C E +G+ + C GF+ P C+YV
Sbjct: 160 --TASCQD--MSCSKQG-----------ECLE---TIGNYTCSCYP-GFYG---PECEYV 197
Query: 410 N-CGGLTPIEDGDVALID--NRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRC 466
CG L + + + ++ + C + + + G + C GIW + P+C
Sbjct: 198 RECGELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQC 257
Query: 467 LFDWCPDPPAVSNASVT-VNGHKA---GSLASYTCENGHILSGSTSVTCTLGGAWSGVPP 522
L CP ++T ++ KA S S++CE G L G V CT G W+ P
Sbjct: 258 LAAQCPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASGVWTAPAP 317
Query: 523 SCKYVNCGT--PTIHKGSFVLINGTTT--YGSIAQFTCEPDYWLNGAEELVCNRDGKWSY 578
CK ++C +H GS Y + F C + L GA+ + C+ G+W+
Sbjct: 318 VCKAISCEPLESPVH-GSMDCSPSLRAFQYDTNCSFRCAEGFMLRGADIVRCDNLGQWTA 376
Query: 579 DIPSCELTSCPEPEVPSGGYME------AFDYYVHSTINFHCEAGHKLIGEPNLVCQQDG 632
P C+ C + VP+ + AF Y S +F C G L+G L C G
Sbjct: 377 PAPVCQALQCQDLPVPNEARVNCSHPFGAFRY--QSVCSFTCNEGLLLVGASVLQCLATG 434
Query: 633 EWSGDSPTCEY----------IDCGKLPTLPYGTMELLN--GTTHLGSVIQYSCTTNYRL 680
W+ P C+ + C L T GTM + GT + + C + L
Sbjct: 435 NWNSVPPECQGKSIASLPTPGVQCPALTTPGQGTMYCRHHPGTFGFNTTCYFGCNAGFTL 494
Query: 681 VGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVG 740
+G +C QW+ +P C ++CS+ + K I N +
Sbjct: 495 IGDSTLSCRPSGQWTAVTPACRAVKCSE-LHVNKPIAMNCSN----------------LW 537
Query: 741 NTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQ 781
+ G++ + C +G + G + + C++NG WS T PTCQ
Sbjct: 538 GNFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTCQ 578
Score = 139 bits (337), Expect = 4e-32
Identities = 105/404 (25%), Positives = 159/404 (39%), Gaps = 38/404 (9%)
Query: 581 PSCE-LTSCPEPEVPSGGYMEAF----DYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWS 635
P CE + C E E+P M ++ +S +FHC G+++ G L C G W+
Sbjct: 192 PECEYVRECGELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPSKLECLASGIWT 251
Query: 636 GDSPTCEYIDCGKLPTLPYGTMELLNGTTHLG--SVIQYSCTTNYRLVGPVRRTCTEEFQ 693
P C C L G M L+ S +SC + LVGP CT
Sbjct: 252 NKPPQCLAAQCPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASGV 311
Query: 694 WSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRC 753
W+ +P C+ I C +P+ E + HG + D ++ +RC
Sbjct: 312 WTAPAPVCKAISC-EPL--ESPV---------HG-----SMDCSPSLRAFQYDTNCSFRC 354
Query: 754 EKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTL--PSNATFYGATAFY 811
+G+ + G + C++ GQW+ P CQ + C + +V P A Y + +
Sbjct: 355 AEGFMLRGADIVRCDNLGQWTAPAPVCQALQCQDLPVPNEARVNCSHPFGAFRYQSVCSF 414
Query: 812 QCDENWELEGVIRRMCQENGTWSLEPPIC--KEI-TCPDPSAQIKA----GSGLLVV--- 861
C+E L G C G W+ PP C K I + P P Q A G G +
Sbjct: 415 TCNEGLLLVGASVLQCLATGNWNSVPPECQGKSIASLPTPGVQCPALTTPGQGTMYCRHH 474
Query: 862 TSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVIS 921
T ++ C G+ L G T +C GQW P C + C + + S
Sbjct: 475 PGTFGFNTTCYFGCNAGFTLIGDSTLSCRPSGQWTAVTPACRAVKCSELHVNKPIAMNCS 534
Query: 922 N--GSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
N G+ +GS ++CL G C ++G WS P+C+
Sbjct: 535 NLWGNFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTCQ 578
Score = 54.8 bits (126), Expect = 2e-06
Identities = 27/109 (24%), Positives = 45/109 (41%), Gaps = 2/109 (1%)
Query: 866 SIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGST 925
S + + C GY + G C++ G W P C+ C E G + + +
Sbjct: 221 SFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQCLAAQCPPLKIPERGNMTCLHSAK 280
Query: 926 LF--GSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCELATNEAVDS 972
F SS + C + VGP + +C G W+ P C+ + E ++S
Sbjct: 281 AFQHQSSCSFSCEEGFALVGPEVVQCTASGVWTAPAPVCKAISCEPLES 329
Score = 35.9 bits (79), Expect = 0.79
Identities = 16/58 (27%), Positives = 28/58 (48%), Gaps = 1/58 (1%)
Query: 2 CGHPAVPPNARVSIPNE-ENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
CG +P + ++ + N + + C +GY++ G + EC G WT +PP C
Sbjct: 200 CGELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQC 257
Score = 35.5 bits (78), Expect = 1.0
Identities = 20/65 (30%), Positives = 31/65 (47%), Gaps = 2/65 (3%)
Query: 1 RCGHPAVPPNARVSIPNEENIVA-GTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC- 58
+C VP ARV+ + ++ + C+EG L GA +C G+W PP C
Sbjct: 385 QCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPECQ 444
Query: 59 GTNVA 63
G ++A
Sbjct: 445 GKSIA 449
Score = 34.3 bits (75), Expect = 2.4
Identities = 12/30 (40%), Positives = 16/30 (53%)
Query: 29 YECDEGYELFGARQRECTLRGDWTLEPPFC 58
+ C+EG+ L G +CT G WT P C
Sbjct: 290 FSCEEGFALVGPEVVQCTASGVWTAPAPVC 319
Score = 32.3 bits (70), Expect = 9.7
Identities = 20/62 (32%), Positives = 27/62 (43%), Gaps = 3/62 (4%)
Query: 20 NIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTNVAFRKPANQSTTVRGGAA 79
N G+I + C EG L G+ Q C G W+ P C A ++ T GGA
Sbjct: 539 NFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTC---QAGPLTIQEALTYFGGAV 595
Query: 80 AN 81
A+
Sbjct: 596 AS 597
>AL022146-6|CAI22756.1| 645|Homo sapiens selectin P (granule
membrane protein 140kDa, antigen CD62) protein.
Length = 645
Score = 152 bits (368), Expect = 8e-36
Identities = 143/581 (24%), Positives = 232/581 (39%), Gaps = 89/581 (15%)
Query: 236 SFDEARKQCQSHGGDLIHGFQGATSSFLTQELERRKAQLKTQLVWIGAQKEPGLTSRTWQ 295
S++ +RK CQ+ DL+ +L + L + WIG +K ++TW
Sbjct: 51 SWNISRKYCQNRYTDLVAIQNKNEIDYLNKVLP-----YYSSYYWIGIRKN----NKTWT 101
Query: 296 WVDGELV---SKPSWGKDQPNNYNGEQNCV---VLDGGRGWLWNDVGCNLDYLHWICQYL 349
WV + +W ++PNN ++CV + WND C L H +C
Sbjct: 102 WVGTKKALTNEAENWADNEPNNKRNNEDCVEIYIKSPSAPGKWNDEHC-LKKKHALCY-- 158
Query: 350 PPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYV 409
T D ++ + G +C E +G+ + C GF+ P C+YV
Sbjct: 159 --TASCQD--MSCSKQG-----------ECLE---TIGNYTCSCYP-GFYG---PECEYV 196
Query: 410 N-CGGLTPIEDGDVALID--NRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRC 466
CG L + + + ++ + C + + + G + C GIW + P+C
Sbjct: 197 RECGELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQC 256
Query: 467 LFDWCPDPPAVSNASVT-VNGHKA---GSLASYTCENGHILSGSTSVTCTLGGAWSGVPP 522
L CP ++T ++ KA S S++CE G L G V CT G W+ P
Sbjct: 257 LAAQCPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASGVWTAPAP 316
Query: 523 SCKYVNCGT--PTIHKGSFVLINGTTT--YGSIAQFTCEPDYWLNGAEELVCNRDGKWSY 578
CK ++C +H GS Y + F C + L GA+ + C+ G+W+
Sbjct: 317 VCKAISCEPLESPVH-GSMDCSPSLRAFQYDTNCSFRCAEGFMLRGADIVRCDNLGQWTA 375
Query: 579 DIPSCELTSCPEPEVPSGGYME------AFDYYVHSTINFHCEAGHKLIGEPNLVCQQDG 632
P C+ C + VP+ + AF Y S +F C G L+G L C G
Sbjct: 376 PAPVCQALQCQDLPVPNEARVNCSHPFGAFRY--QSVCSFTCNEGLLLVGASVLQCLATG 433
Query: 633 EWSGDSPTCEY----------IDCGKLPTLPYGTMELLN--GTTHLGSVIQYSCTTNYRL 680
W+ P C+ + C L T GTM + GT + + C + L
Sbjct: 434 NWNSVPPECQGKSIASLPTPGVQCPALTTPGQGTMYCRHHPGTFGFNTTCYFGCNAGFTL 493
Query: 681 VGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVG 740
+G +C QW+ +P C ++CS+ + K I N +
Sbjct: 494 IGDSTLSCRPSGQWTAVTPACRAVKCSE-LHVNKPIAMNCSN----------------LW 536
Query: 741 NTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQ 781
+ G++ + C +G + G + + C++NG WS T PTCQ
Sbjct: 537 GNFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTCQ 577
Score = 139 bits (337), Expect = 4e-32
Identities = 105/404 (25%), Positives = 159/404 (39%), Gaps = 38/404 (9%)
Query: 581 PSCE-LTSCPEPEVPSGGYMEAF----DYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWS 635
P CE + C E E+P M ++ +S +FHC G+++ G L C G W+
Sbjct: 191 PECEYVRECGELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPSKLECLASGIWT 250
Query: 636 GDSPTCEYIDCGKLPTLPYGTMELLNGTTHLG--SVIQYSCTTNYRLVGPVRRTCTEEFQ 693
P C C L G M L+ S +SC + LVGP CT
Sbjct: 251 NKPPQCLAAQCPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASGV 310
Query: 694 WSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRC 753
W+ +P C+ I C +P+ E + HG + D ++ +RC
Sbjct: 311 WTAPAPVCKAISC-EPL--ESPV---------HG-----SMDCSPSLRAFQYDTNCSFRC 353
Query: 754 EKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTL--PSNATFYGATAFY 811
+G+ + G + C++ GQW+ P CQ + C + +V P A Y + +
Sbjct: 354 AEGFMLRGADIVRCDNLGQWTAPAPVCQALQCQDLPVPNEARVNCSHPFGAFRYQSVCSF 413
Query: 812 QCDENWELEGVIRRMCQENGTWSLEPPIC--KEI-TCPDPSAQIKA----GSGLLVV--- 861
C+E L G C G W+ PP C K I + P P Q A G G +
Sbjct: 414 TCNEGLLLVGASVLQCLATGNWNSVPPECQGKSIASLPTPGVQCPALTTPGQGTMYCRHH 473
Query: 862 TSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVIS 921
T ++ C G+ L G T +C GQW P C + C + + S
Sbjct: 474 PGTFGFNTTCYFGCNAGFTLIGDSTLSCRPSGQWTAVTPACRAVKCSELHVNKPIAMNCS 533
Query: 922 N--GSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
N G+ +GS ++CL G C ++G WS P+C+
Sbjct: 534 NLWGNFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTCQ 577
Score = 54.8 bits (126), Expect = 2e-06
Identities = 27/109 (24%), Positives = 45/109 (41%), Gaps = 2/109 (1%)
Query: 866 SIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGST 925
S + + C GY + G C++ G W P C+ C E G + + +
Sbjct: 220 SFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQCLAAQCPPLKIPERGNMTCLHSAK 279
Query: 926 LF--GSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCELATNEAVDS 972
F SS + C + VGP + +C G W+ P C+ + E ++S
Sbjct: 280 AFQHQSSCSFSCEEGFALVGPEVVQCTASGVWTAPAPVCKAISCEPLES 328
Score = 35.9 bits (79), Expect = 0.79
Identities = 16/58 (27%), Positives = 28/58 (48%), Gaps = 1/58 (1%)
Query: 2 CGHPAVPPNARVSIPNE-ENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
CG +P + ++ + N + + C +GY++ G + EC G WT +PP C
Sbjct: 199 CGELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQC 256
Score = 35.5 bits (78), Expect = 1.0
Identities = 20/65 (30%), Positives = 31/65 (47%), Gaps = 2/65 (3%)
Query: 1 RCGHPAVPPNARVSIPNEENIVA-GTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC- 58
+C VP ARV+ + ++ + C+EG L GA +C G+W PP C
Sbjct: 384 QCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPECQ 443
Query: 59 GTNVA 63
G ++A
Sbjct: 444 GKSIA 448
Score = 34.3 bits (75), Expect = 2.4
Identities = 12/30 (40%), Positives = 16/30 (53%)
Query: 29 YECDEGYELFGARQRECTLRGDWTLEPPFC 58
+ C+EG+ L G +CT G WT P C
Sbjct: 289 FSCEEGFALVGPEVVQCTASGVWTAPAPVC 318
Score = 32.3 bits (70), Expect = 9.7
Identities = 20/62 (32%), Positives = 27/62 (43%), Gaps = 3/62 (4%)
Query: 20 NIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTNVAFRKPANQSTTVRGGAA 79
N G+I + C EG L G+ Q C G W+ P C A ++ T GGA
Sbjct: 538 NFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTC---QAGPLTIQEALTYFGGAV 594
Query: 80 AN 81
A+
Sbjct: 595 AS 596
>AL022146-4|CAI22755.1| 646|Homo sapiens selectin P (granule
membrane protein 140kDa, antigen CD62) protein.
Length = 646
Score = 152 bits (368), Expect = 8e-36
Identities = 143/581 (24%), Positives = 232/581 (39%), Gaps = 89/581 (15%)
Query: 236 SFDEARKQCQSHGGDLIHGFQGATSSFLTQELERRKAQLKTQLVWIGAQKEPGLTSRTWQ 295
S++ +RK CQ+ DL+ +L + L + WIG +K ++TW
Sbjct: 52 SWNISRKYCQNRYTDLVAIQNKNEIDYLNKVLP-----YYSSYYWIGIRKN----NKTWT 102
Query: 296 WVDGELV---SKPSWGKDQPNNYNGEQNCV---VLDGGRGWLWNDVGCNLDYLHWICQYL 349
WV + +W ++PNN ++CV + WND C L H +C
Sbjct: 103 WVGTKKALTNEAENWADNEPNNKRNNEDCVEIYIKSPSAPGKWNDEHC-LKKKHALCY-- 159
Query: 350 PPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYV 409
T D ++ + G +C E +G+ + C GF+ P C+YV
Sbjct: 160 --TASCQD--MSCSKQG-----------ECLE---TIGNYTCSCYP-GFYG---PECEYV 197
Query: 410 N-CGGLTPIEDGDVALID--NRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRC 466
CG L + + + ++ + C + + + G + C GIW + P+C
Sbjct: 198 RECGELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQC 257
Query: 467 LFDWCPDPPAVSNASVT-VNGHKA---GSLASYTCENGHILSGSTSVTCTLGGAWSGVPP 522
L CP ++T ++ KA S S++CE G L G V CT G W+ P
Sbjct: 258 LAAQCPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASGVWTAPAP 317
Query: 523 SCKYVNCGT--PTIHKGSFVLINGTTT--YGSIAQFTCEPDYWLNGAEELVCNRDGKWSY 578
CK ++C +H GS Y + F C + L GA+ + C+ G+W+
Sbjct: 318 VCKAISCEPLESPVH-GSMDCSPSLRAFQYDTNCSFRCAEGFMLRGADIVRCDNLGQWTA 376
Query: 579 DIPSCELTSCPEPEVPSGGYME------AFDYYVHSTINFHCEAGHKLIGEPNLVCQQDG 632
P C+ C + VP+ + AF Y S +F C G L+G L C G
Sbjct: 377 PAPVCQALQCQDLPVPNEARVNCSHPFGAFRY--QSVCSFTCNEGLLLVGASVLQCLATG 434
Query: 633 EWSGDSPTCEY----------IDCGKLPTLPYGTMELLN--GTTHLGSVIQYSCTTNYRL 680
W+ P C+ + C L T GTM + GT + + C + L
Sbjct: 435 NWNSVPPECQGKSIASLPTPGVQCPALTTPGQGTMYCRHHPGTFGFNTTCYFGCNAGFTL 494
Query: 681 VGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVG 740
+G +C QW+ +P C ++CS+ + K I N +
Sbjct: 495 IGDSTLSCRPSGQWTAVTPACRAVKCSE-LHVNKPIAMNCSN----------------LW 537
Query: 741 NTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQ 781
+ G++ + C +G + G + + C++NG WS T PTCQ
Sbjct: 538 GNFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTCQ 578
Score = 139 bits (337), Expect = 4e-32
Identities = 105/404 (25%), Positives = 159/404 (39%), Gaps = 38/404 (9%)
Query: 581 PSCE-LTSCPEPEVPSGGYMEAF----DYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWS 635
P CE + C E E+P M ++ +S +FHC G+++ G L C G W+
Sbjct: 192 PECEYVRECGELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPSKLECLASGIWT 251
Query: 636 GDSPTCEYIDCGKLPTLPYGTMELLNGTTHLG--SVIQYSCTTNYRLVGPVRRTCTEEFQ 693
P C C L G M L+ S +SC + LVGP CT
Sbjct: 252 NKPPQCLAAQCPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASGV 311
Query: 694 WSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRC 753
W+ +P C+ I C +P+ E + HG + D ++ +RC
Sbjct: 312 WTAPAPVCKAISC-EPL--ESPV---------HG-----SMDCSPSLRAFQYDTNCSFRC 354
Query: 754 EKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTL--PSNATFYGATAFY 811
+G+ + G + C++ GQW+ P CQ + C + +V P A Y + +
Sbjct: 355 AEGFMLRGADIVRCDNLGQWTAPAPVCQALQCQDLPVPNEARVNCSHPFGAFRYQSVCSF 414
Query: 812 QCDENWELEGVIRRMCQENGTWSLEPPIC--KEI-TCPDPSAQIKA----GSGLLVV--- 861
C+E L G C G W+ PP C K I + P P Q A G G +
Sbjct: 415 TCNEGLLLVGASVLQCLATGNWNSVPPECQGKSIASLPTPGVQCPALTTPGQGTMYCRHH 474
Query: 862 TSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVIS 921
T ++ C G+ L G T +C GQW P C + C + + S
Sbjct: 475 PGTFGFNTTCYFGCNAGFTLIGDSTLSCRPSGQWTAVTPACRAVKCSELHVNKPIAMNCS 534
Query: 922 N--GSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
N G+ +GS ++CL G C ++G WS P+C+
Sbjct: 535 NLWGNFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTCQ 578
Score = 54.8 bits (126), Expect = 2e-06
Identities = 27/109 (24%), Positives = 45/109 (41%), Gaps = 2/109 (1%)
Query: 866 SIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGST 925
S + + C GY + G C++ G W P C+ C E G + + +
Sbjct: 221 SFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQCLAAQCPPLKIPERGNMTCLHSAK 280
Query: 926 LF--GSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCELATNEAVDS 972
F SS + C + VGP + +C G W+ P C+ + E ++S
Sbjct: 281 AFQHQSSCSFSCEEGFALVGPEVVQCTASGVWTAPAPVCKAISCEPLES 329
Score = 35.9 bits (79), Expect = 0.79
Identities = 16/58 (27%), Positives = 28/58 (48%), Gaps = 1/58 (1%)
Query: 2 CGHPAVPPNARVSIPNE-ENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
CG +P + ++ + N + + C +GY++ G + EC G WT +PP C
Sbjct: 200 CGELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQC 257
Score = 35.5 bits (78), Expect = 1.0
Identities = 20/65 (30%), Positives = 31/65 (47%), Gaps = 2/65 (3%)
Query: 1 RCGHPAVPPNARVSIPNEENIVA-GTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC- 58
+C VP ARV+ + ++ + C+EG L GA +C G+W PP C
Sbjct: 385 QCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPECQ 444
Query: 59 GTNVA 63
G ++A
Sbjct: 445 GKSIA 449
Score = 34.3 bits (75), Expect = 2.4
Identities = 12/30 (40%), Positives = 16/30 (53%)
Query: 29 YECDEGYELFGARQRECTLRGDWTLEPPFC 58
+ C+EG+ L G +CT G WT P C
Sbjct: 290 FSCEEGFALVGPEVVQCTASGVWTAPAPVC 319
Score = 32.3 bits (70), Expect = 9.7
Identities = 20/62 (32%), Positives = 27/62 (43%), Gaps = 3/62 (4%)
Query: 20 NIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTNVAFRKPANQSTTVRGGAA 79
N G+I + C EG L G+ Q C G W+ P C A ++ T GGA
Sbjct: 539 NFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTC---QAGPLTIQEALTYFGGAV 595
Query: 80 AN 81
A+
Sbjct: 596 AS 597
>AL021940-5|CAI19359.1| 547|Homo sapiens selectin E (endothelial
adhesion molecule 1) protein.
Length = 547
Score = 149 bits (360), Expect = 7e-35
Identities = 90/292 (30%), Positives = 122/292 (41%), Gaps = 17/292 (5%)
Query: 365 LGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVAL 424
LGN + S C G++ ++ C G WS P+C V C +T +G V
Sbjct: 197 LGN-FSYNSSCSISCDRGYLPSSMETMQCMSSGEWSAPIPACNVVECDAVTNPANGFVEC 255
Query: 425 IDNRTTH--GARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASV 482
N + + C E F L+G C G WD E P C C N SV
Sbjct: 256 FQNPGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGNWDNEKPTCKAVTCRAVRQPQNGSV 315
Query: 483 TVNGHKAG-----SLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTIHKG 537
+ AG S ++TCE G +L G V CT G W+ P C+ V C +H+
Sbjct: 316 RCSHSPAGEFTFKSSCNFTCEEGFMLQGPAQVECTTQGQWTQQIPVCEAVRCDA--VHQP 373
Query: 538 SFVLIN------GTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEP 591
L+ G TY S F+CE + L+G+ +L C G+W+ ++PSC++ C
Sbjct: 374 PKGLVRCAHSPIGEFTYKSSCAFSCEEGFELHGSTQLECTSQGQWTEEVPSCQVVKCSSL 433
Query: 592 EVPSGGYMEAFDYYVHSTI-NFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCE 642
VP M V T+ F C G L G C G WSG PTCE
Sbjct: 434 AVPGKINMSCSGEPVFGTVCKFACPEGWTLNGSAARTCGATGHWSGLLPTCE 485
Score = 140 bits (340), Expect = 2e-32
Identities = 82/302 (27%), Positives = 127/302 (42%), Gaps = 31/302 (10%)
Query: 491 SLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTIHKGSFVLI---NGTTT 547
S S +C+ G++ S ++ C G WS P+C V C T FV G+
Sbjct: 204 SSCSISCDRGYLPSSMETMQCMSSGEWSAPIPACNVVECDAVTNPANGFVECFQNPGSFP 263
Query: 548 YGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGG-----YMEAF 602
+ + F CE + L GA+ L C G W + P+C+ +C P G + A
Sbjct: 264 WNTTCTFDCEEGFELMGAQSLQCTSSGNWDNEKPTCKAVTCRAVRQPQNGSVRCSHSPAG 323
Query: 603 DYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLN- 661
++ S+ NF CE G L G + C G+W+ P CE + C + P G + +
Sbjct: 324 EFTFKSSCNFTCEEGFMLQGPAQVECTTQGQWTQQIPVCEAVRCDAVHQPPKGLVRCAHS 383
Query: 662 --GTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSV 719
G S +SC + L G + CT + QW++ P C+ ++CS V K +S
Sbjct: 384 PIGEFTYKSSCAFSCEEGFELHGSTQLECTSQGQWTEEVPSCQVVKCSSLAVPGKINMSC 443
Query: 720 TGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPT 779
+G G + K+ C +G+ + G + TC G WSG PT
Sbjct: 444 SGEP--------------------VFGTVCKFACPEGWTLNGSAARTCGATGHWSGLLPT 483
Query: 780 CQ 781
C+
Sbjct: 484 CE 485
Score = 138 bits (334), Expect = 1e-31
Identities = 125/507 (24%), Positives = 190/507 (37%), Gaps = 56/507 (11%)
Query: 236 SFDEARKQCQSHGGDLIHGFQGATSSFLTQELERRKAQLKTQLVWIGAQKEPGLTSRTWQ 295
++DEA CQ L+ +L L WIG +K + W
Sbjct: 32 TYDEASAYCQQRYTHLVAIQNKEEIEYLNSILS-----YSPSYYWIGIRK----VNNVWV 82
Query: 296 WVDGE---LVSKPSWGKDQPNNYNGEQNCVVLDGGRG---WLWNDVGCNLDYLHWICQYL 349
WV + +W +PNN +++CV + R +WND C+ L +C
Sbjct: 83 WVGTQKPLTEEAKNWAPGEPNNRQKDEDCVEIYIKREKDVGMWNDERCSKKKLA-LCYTA 141
Query: 350 PPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYV 409
T NT+ G+ +C E + CK D +SG + V
Sbjct: 142 ACT--------NTSCSGHG---------ECVETI-----NNYTCKCDPGFSGLKCE-QIV 178
Query: 410 NCGGLTPIEDGDVALID--NRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL 467
NC L E G + ++ + SC + C G W P C
Sbjct: 179 NCTALESPEHGSLVCSHPLGNFSYNSSCSISCDRGYLPSSMETMQCMSSGEWSAPIPACN 238
Query: 468 FDWCPDPPAVSNASVTVNGHKAG----SLASYTCENGHILSGSTSVTCTLGGAWSGVPPS 523
C +N V + + ++ CE G L G+ S+ CT G W P+
Sbjct: 239 VVECDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGNWDNEKPT 298
Query: 524 CKYVNCGTPTIHKGSFVLIN----GTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYD 579
CK V C + V + G T+ S FTCE + L G ++ C G+W+
Sbjct: 299 CKAVTCRAVRQPQNGSVRCSHSPAGEFTFKSSCNFTCEEGFMLQGPAQVECTTQGQWTQQ 358
Query: 580 IPSCELTSCPEPEVPSGGYMEAF-----DYYVHSTINFHCEAGHKLIGEPNLVCQQDGEW 634
IP CE C P G + ++ S+ F CE G +L G L C G+W
Sbjct: 359 IPVCEAVRCDAVHQPPKGLVRCAHSPIGEFTYKSSCAFSCEEGFELHGSTQLECTSQGQW 418
Query: 635 SGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQW 694
+ + P+C+ + C L +P +G G+V +++C + L G RTC W
Sbjct: 419 TEEVPSCQVVKCSSL-AVPGKINMSCSGEPVFGTVCKFACPEGWTLNGSAARTCGATGHW 477
Query: 695 SDSSPRCEEIRCSD-PIVAEKSIVSVT 720
S P CE S+ P+VA S ++
Sbjct: 478 SGLLPTCEAPTESNIPLVAGLSAAGLS 504
Score = 118 bits (285), Expect = 9e-26
Identities = 100/380 (26%), Positives = 149/380 (39%), Gaps = 40/380 (10%)
Query: 605 YVHSTINFHCEAGHKLIGEP--NLVCQQDGEWSGDSPTCEYI-DCGKLPTLPYGTMELLN 661
Y + N C +GH E N C+ D +SG CE I +C L + +G++ +
Sbjct: 139 YTAACTNTSC-SGHGECVETINNYTCKCDPGFSGLK--CEQIVNCTALESPEHGSLVCSH 195
Query: 662 --GTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSV 719
G S SC Y C +WS P C + C V
Sbjct: 196 PLGNFSYNSSCSISCDRGYLPSSMETMQCMSSGEWSAPIPACNVVECDAVTNPANGFVEC 255
Query: 720 TGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPT 779
N S T D CE+G++++G C +G W PT
Sbjct: 256 FQNPGSFPWNTTCTFD-----------------CEEGFELMGAQSLQCTSSGNWDNEKPT 298
Query: 780 CQYVDCGNPGRIENGKVTL---PSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLE 836
C+ V C + +NG V P+ + ++ + C+E + L+G + C G W+ +
Sbjct: 299 CKAVTCRAVRQPQNGSVRCSHSPAGEFTFKSSCNFTCEEGFMLQGPAQVECTTQGQWTQQ 358
Query: 837 PPICKEITCPDPSAQIKAGSGLLVVTSTLSIG-----GEAHYQCERGYNLKGHQTRTCIS 891
P+C+ + C D Q G LV + IG + CE G+ L G C S
Sbjct: 359 IPVCEAVRC-DAVHQPPKG---LVRCAHSPIGEFTYKSSCAFSCEEGFELHGSTQLECTS 414
Query: 892 KGQWNGTVPVCIPIDCRSPGNIENGKIVIS-NGSTLFGSSVEYYCLSQYQRVGPFLRKCL 950
+GQW VP C + C S GKI +S +G +FG+ ++ C + G R C
Sbjct: 415 QGQWTEEVPSCQVVKCSSLA--VPGKINMSCSGEPVFGTVCKFACPEGWTLNGSAARTCG 472
Query: 951 DDGRWSGEEPSCELATNEAV 970
G WSG P+CE T +
Sbjct: 473 ATGHWSGLLPTCEAPTESNI 492
Score = 46.4 bits (105), Expect = 6e-04
Identities = 26/73 (35%), Positives = 35/73 (47%), Gaps = 3/73 (4%)
Query: 2 CGHPAVPPNARVS-IPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCG- 59
C P N V N + T ++C+EG+EL GA+ +CT G+W E P C
Sbjct: 242 CDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGNWDNEKPTCKA 301
Query: 60 -TNVAFRKPANQS 71
T A R+P N S
Sbjct: 302 VTCRAVRQPQNGS 314
Score = 44.0 bits (99), Expect = 0.003
Identities = 16/30 (53%), Positives = 21/30 (70%)
Query: 29 YECDEGYELFGARQRECTLRGDWTLEPPFC 58
+ C+EG+EL G+ Q ECT +G WT E P C
Sbjct: 396 FSCEEGFELHGSTQLECTSQGQWTEEVPSC 425
Score = 38.3 bits (85), Expect = 0.15
Identities = 14/30 (46%), Positives = 19/30 (63%)
Query: 29 YECDEGYELFGARQRECTLRGDWTLEPPFC 58
+ C+EG+ L G Q ECT +G WT + P C
Sbjct: 333 FTCEEGFMLQGPAQVECTTQGQWTQQIPVC 362
Score = 38.3 bits (85), Expect = 0.15
Identities = 20/58 (34%), Positives = 27/58 (46%), Gaps = 2/58 (3%)
Query: 1 RCGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
+C AVP +S E V GT+ + C EG+ L G+ R C G W+ P C
Sbjct: 429 KCSSLAVPGKINMSCSGEP--VFGTVCKFACPEGWTLNGSAARTCGATGHWSGLLPTC 484
>AK095627-1|BAC04593.1| 505|Homo sapiens protein ( Homo sapiens
cDNA FLJ38308 fis, clone FCBBF3019085, weakly similar to
E-SELECTIN PRECURSOR. ).
Length = 505
Score = 139 bits (336), Expect = 6e-32
Identities = 84/261 (32%), Positives = 114/261 (43%), Gaps = 7/261 (2%)
Query: 452 TCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTC 511
+C + W+G P C C PP + N V + GS +Y C G+ LS TC
Sbjct: 11 SCTKDRTWNGTKPVCKALMCKPPPLIPNGKVVGSDFMWGSSVTYACLEGYQLSLPAVFTC 70
Query: 512 TLGGAWSGVPPSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCN 571
G+W+G P C V CG P + G +Y S F+C P L G+ C
Sbjct: 71 EGNGSWTGELPQCFPVFCGDPGVPSRGRREDRG-FSYRSSVSFSCHPPLVLVGSPRRFCQ 129
Query: 572 RDGKWSYDIPSC---ELTSCPEPEVPSGGYM-EAFDYYVHSTINFHCEAGHKLIGEPNLV 627
DG WS PSC LT+C +P VP G + Y V ST+ F C+ G+ L G
Sbjct: 130 SDGTWSGTQPSCIDPTLTTCADPGVPQFGIQNNSQGYQVGSTVLFRCQKGYLLQGSTTRT 189
Query: 628 CQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLV-GPVRR 686
C + WSG P C C + T + + L+ +G + YSC + L G R
Sbjct: 190 CLPNLTWSGTPPDCVPHHCRQPETPTHANVGALD-LPSMGYTLIYSCQEGFSLKGGSEHR 248
Query: 687 TCTEEFQWSDSSPRCEEIRCS 707
TC + W+ P C E+R S
Sbjct: 249 TCKADGSWTGKPPICLEVRPS 269
Score = 133 bits (321), Expect = 4e-30
Identities = 85/286 (29%), Positives = 128/286 (44%), Gaps = 35/286 (12%)
Query: 626 LVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVR 685
L C +D W+G P C+ + C P +P G +++ GS + Y+C Y+L P
Sbjct: 10 LSCTKDRTWNGTKPVCKALMCKPPPLIPNG--KVVGSDFMWGSSVTYACLEGYQLSLPAV 67
Query: 686 RTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRI 745
TC W+ P+C + C DP V S G D G +YR
Sbjct: 68 FTCEGNGSWTGELPQCFPVFCGDPGVP------------SRGR-------REDRGFSYR- 107
Query: 746 GALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTC---QYVDCGNPGRIENGKVTLPSNA 802
+ V + C ++G C+ +G WSGT P+C C +PG + G + +N+
Sbjct: 108 -SSVSFSCHPPLVLVGSPRRFCQSDGTWSGTQPSCIDPTLTTCADPGVPQFG---IQNNS 163
Query: 803 TFY--GATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLV 860
Y G+T ++C + + L+G R C N TWS PP C C P A G L
Sbjct: 164 QGYQVGSTVLFRCQKGYLLQGSTTRTCLPNLTWSGTPPDCVPHHCRQPETPTHANVGALD 223
Query: 861 VTSTLSIGGEAHYQCERGYNLKG-HQTRTCISKGQWNGTVPVCIPI 905
+ S +G Y C+ G++LKG + RTC + G W G P+C+ +
Sbjct: 224 LPS---MGYTLIYSCQEGFSLKGGSEHRTCKADGSWTGKPPICLEV 266
Score = 133 bits (321), Expect = 4e-30
Identities = 81/280 (28%), Positives = 127/280 (45%), Gaps = 31/280 (11%)
Query: 687 TCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIG 746
+CT++ W+ + P C+ + C P + V VG+ + G
Sbjct: 11 SCTKDRTWNGTKPVCKALMCKPPPLIPNGKV---------------------VGSDFMWG 49
Query: 747 ALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYG 806
+ V Y C +GY++ ++ TCE NG W+G P C V CG+PG G+ Y
Sbjct: 50 SSVTYACLEGYQLSLPAVFTCEGNGSWTGELPQCFPVFCGDPGVPSRGR--REDRGFSYR 107
Query: 807 ATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKE---ITCPDPSAQIKAGSGLLVVTS 863
++ + C L G RR CQ +GTWS P C + TC DP G+ +
Sbjct: 108 SSVSFSCHPPLVLVGSPRRFCQSDGTWSGTQPSCIDPTLTTCADPGV---PQFGIQNNSQ 164
Query: 864 TLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNG 923
+G ++C++GY L+G TRTC+ W+GT P C+P CR P + + +
Sbjct: 165 GYQVGSTVLFRCQKGYLLQGSTTRTCLPNLTWSGTPPDCVPHHCRQPETPTHANVGALDL 224
Query: 924 STLFGSSVEYYCLSQYQ-RVGPFLRKCLDDGRWSGEEPSC 962
++ G ++ Y C + + G R C DG W+G+ P C
Sbjct: 225 PSM-GYTLIYSCQEGFSLKGGSEHRTCKADGSWTGKPPIC 263
Score = 127 bits (307), Expect = 2e-28
Identities = 79/256 (30%), Positives = 109/256 (42%), Gaps = 11/256 (4%)
Query: 393 CKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERT 452
C KD W+G P CK + C I +G V + + G+ Y+C E + L T
Sbjct: 12 CTKDRTWNGTKPVCKALMCKPPPLIPNGKV--VGSDFMWGSSVTYACLEGYQLSLPAVFT 69
Query: 453 CGDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCT 512
C G W GE P+C +C DP S G S S++C +L GS C
Sbjct: 70 CEGNGSWTGELPQCFPVFCGDPGVPSRGRREDRGFSYRSSVSFSCHPPLVLVGSPRRFCQ 129
Query: 513 LGGAWSGVPPSC---KYVNCGTPTIHKGSFVLINGTTTY--GSIAQFTCEPDYWLNGAEE 567
G WSG PSC C P + + F + N + Y GS F C+ Y L G+
Sbjct: 130 SDGTWSGTQPSCIDPTLTTCADPGVPQ--FGIQNNSQGYQVGSTVLFRCQKGYLLQGSTT 187
Query: 568 LVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFDY-YVHSTINFHCEAGHKLI-GEPN 625
C + WS P C C +PE P+ + A D + T+ + C+ G L G +
Sbjct: 188 RTCLPNLTWSGTPPDCVPHHCRQPETPTHANVGALDLPSMGYTLIYSCQEGFSLKGGSEH 247
Query: 626 LVCQQDGEWSGDSPTC 641
C+ DG W+G P C
Sbjct: 248 RTCKADGSWTGKPPIC 263
Score = 126 bits (305), Expect = 3e-28
Identities = 78/276 (28%), Positives = 116/276 (42%), Gaps = 26/276 (9%)
Query: 509 VTCTLGGAWSGVPPSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEEL 568
++CT W+G P CK + C P + V + +GS + C Y L+
Sbjct: 10 LSCTKDRTWNGTKPVCKALMCKPPPLIPNGKV-VGSDFMWGSSVTYACLEGYQLSLPAVF 68
Query: 569 VCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVC 628
C +G W+ ++P C C +P VPS G E + S+++F C L+G P C
Sbjct: 69 TCEGNGSWTGELPQCFPVFCGDPGVPSRGRREDRGFSYRSSVSFSCHPPLVLVGSPRRFC 128
Query: 629 QQDGEWSGDSPTC---EYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVR 685
Q DG WSG P+C C P +P ++ + +GS + + C Y L G
Sbjct: 129 QSDGTWSGTQPSCIDPTLTTCAD-PGVPQFGIQNNSQGYQVGSTVLFRCQKGYLLQGSTT 187
Query: 686 RTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRI 745
RTC WS + P C C P + V + S G+TLI
Sbjct: 188 RTCLPNLTWSGTPPDCVPHHCRQPETPTHANVGAL-DLPSMGYTLI-------------- 232
Query: 746 GALVKYRCEKGYKVIGES-LSTCEDNGQWSGTTPTC 780
Y C++G+ + G S TC+ +G W+G P C
Sbjct: 233 -----YSCQEGFSLKGGSEHRTCKADGSWTGKPPIC 263
Score = 125 bits (301), Expect = 1e-27
Identities = 74/245 (30%), Positives = 110/245 (44%), Gaps = 11/245 (4%)
Query: 345 ICQYLPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPP 404
+C+ L C P + N ++G+D+ GS + Y C EG+ L C+ +G W+G P
Sbjct: 24 VCKAL--MCKPPPLIPNGKVVGSDFMWGSSVTYACLEGYQLSLPAVFTCEGNGSWTGELP 81
Query: 405 SCKYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAP 464
C V CG P D ++ + +SC LVG+P R C +G W G P
Sbjct: 82 QCFPVFCG--DPGVPSRGRREDRGFSYRSSVSFSCHPPLVLVGSPRRFCQSDGTWSGTQP 139
Query: 465 RCL---FDWCPDPPAVSNASVTVN--GHKAGSLASYTCENGHILSGSTSVTCTLGGAWSG 519
C+ C D P V + N G++ GS + C+ G++L GST+ TC WSG
Sbjct: 140 SCIDPTLTTCAD-PGVPQFGIQNNSQGYQVGSTVLFRCQKGYLLQGSTTRTCLPNLTWSG 198
Query: 520 VPPSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWL-NGAEELVCNRDGKWSY 578
PP C +C P + V + G ++C+ + L G+E C DG W+
Sbjct: 199 TPPDCVPHHCRQPETPTHANVGALDLPSMGYTLIYSCQEGFSLKGGSEHRTCKADGSWTG 258
Query: 579 DIPSC 583
P C
Sbjct: 259 KPPIC 263
Score = 97.9 bits (233), Expect = 2e-19
Identities = 63/203 (31%), Positives = 87/203 (42%), Gaps = 10/203 (4%)
Query: 763 SLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGV 822
S+ +C + W+GT P C+ + C P I NGKV + +G++ Y C E ++L
Sbjct: 8 SVLSCTKDRTWNGTKPVCKALMCKPPPLIPNGKVV--GSDFMWGSSVTYACLEGYQLSLP 65
Query: 823 IRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLK 882
C+ NG+W+ E P C + C DP + S + C L
Sbjct: 66 AVFTCEGNGSWTGELPQCFPVFCGDPGVPSRGRR----EDRGFSYRSSVSFSCHPPLVLV 121
Query: 883 GHQTRTCISKGQWNGTVPVCIP---IDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQY 939
G R C S G W+GT P CI C PG + G S G + GS+V + C Y
Sbjct: 122 GSPRRFCQSDGTWSGTQPSCIDPTLTTCADPGVPQFGIQNNSQGYQV-GSTVLFRCQKGY 180
Query: 940 QRVGPFLRKCLDDGRWSGEEPSC 962
G R CL + WSG P C
Sbjct: 181 LLQGSTTRTCLPNLTWSGTPPDC 203
Score = 77.0 bits (181), Expect = 3e-13
Identities = 37/100 (37%), Positives = 55/100 (55%), Gaps = 2/100 (2%)
Query: 369 YDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNR 428
Y VGS ++++C +G++L G +R C + WSG PP C +C +V +D
Sbjct: 166 YQVGSTVLFRCQKGYLLQGSTTRTCLPNLTWSGTPPDCVPHHCRQPETPTHANVGALD-L 224
Query: 429 TTHGARALYSCRENFTLVGNPE-RTCGDEGIWDGEAPRCL 467
+ G +YSC+E F+L G E RTC +G W G+ P CL
Sbjct: 225 PSMGYTLIYSCQEGFSLKGGSEHRTCKADGSWTGKPPICL 264
Score = 45.6 bits (103), Expect = 0.001
Identities = 23/67 (34%), Positives = 32/67 (47%), Gaps = 2/67 (2%)
Query: 349 LPPTCGSPDKLLNTTILGNDY-DVGSRIVYKCPEGHMLLG-DKSRHCKKDGFWSGAPPSC 406
+P C P+ + + D +G ++Y C EG L G + R CK DG W+G PP C
Sbjct: 204 VPHHCRQPETPTHANVGALDLPSMGYTLIYSCQEGFSLKGGSEHRTCKADGSWTGKPPIC 263
Query: 407 KYVNCGG 413
V G
Sbjct: 264 LEVRPSG 270
Score = 41.5 bits (93), Expect = 0.016
Identities = 20/58 (34%), Positives = 28/58 (48%), Gaps = 3/58 (5%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQ-RECTLRGDWTLEPPFC 58
C P P +A V + ++ G +Y C EG+ L G + R C G WT +PP C
Sbjct: 208 CRQPETPTHANVGALDLPSM--GYTLIYSCQEGFSLKGGSEHRTCKADGSWTGKPPIC 263
Score = 35.1 bits (77), Expect = 1.4
Identities = 17/57 (29%), Positives = 25/57 (43%), Gaps = 2/57 (3%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C P VP + N + G+ ++ C +GY L G+ R C W+ PP C
Sbjct: 149 CADPGVPQFGIQN--NSQGYQVGSTVLFRCQKGYLLQGSTTRTCLPNLTWSGTPPDC 203
Score = 32.7 bits (71), Expect = 7.4
Identities = 19/57 (33%), Positives = 25/57 (43%), Gaps = 3/57 (5%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C P + PN +V + + G+ Y C EGY+L C G WT E P C
Sbjct: 30 CKPPPLIPNGKVV---GSDFMWGSSVTYACLEGYQLSLPAVFTCEGNGSWTGELPQC 83
>AL021940-3|CAI19357.1| 485|Homo sapiens selectin E (endothelial
adhesion molecule 1) protein.
Length = 485
Score = 133 bits (322), Expect = 3e-30
Identities = 117/427 (27%), Positives = 165/427 (38%), Gaps = 55/427 (12%)
Query: 236 SFDEARKQCQSHGGDLIHGFQGATSSFLTQELERRKAQLKTQLVWIGAQKEPGLTSRTWQ 295
++DEA CQ L+ +L L WIG +K + W
Sbjct: 32 TYDEASAYCQQRYTHLVAIQNKEEIEYLNSILS-----YSPSYYWIGIRK----VNNVWV 82
Query: 296 WVDGE---LVSKPSWGKDQPNNYNGEQNCVVLDGGRG---WLWNDVGCNLDYLHWICQYL 349
WV + +W +PNN +++CV + R +WND C+ L +C
Sbjct: 83 WVGTQKPLTEEAKNWAPGEPNNRQKDEDCVEIYIKREKDVGMWNDERCSKKKLA-LCYTA 141
Query: 350 PPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYV 409
T NT+ G+ +C E + CK D +SG + V
Sbjct: 142 ACT--------NTSCSGHG---------ECVETI-----NNYTCKCDPGFSGLKCE-QMV 178
Query: 410 NCGGLTPIEDGDVALIDNRTTH--GARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL 467
C +T +G V N + + C E F L+G C G WD E P C
Sbjct: 179 ECDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGNWDNEKPTCK 238
Query: 468 FDWCPDPPAVSNASVTVNGHKAG-----SLASYTCENGHILSGSTSVTCTLGGAWSGVPP 522
C N SV + AG S ++TCE G +L G V CT G W+ P
Sbjct: 239 AVTCRAVRQPQNGSVRCSHSPAGEFTFKSSCNFTCEEGFMLQGPAQVECTTQGQWTQQIP 298
Query: 523 SCKYVNCGTPTIHKGSFVLIN------GTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKW 576
C+ V C +H+ L+ G TY S F+CE + L+G+ +L C G+W
Sbjct: 299 VCEAVRCDA--VHQPPKGLVRCAHSPIGEFTYKSSCAFSCEEGFELHGSTQLECTSQGQW 356
Query: 577 SYDIPSCELTSCPEPEVPSGGYMEAFDYYVHSTI-NFHCEAGHKLIGEPNLVCQQDGEWS 635
+ ++PSC++ C VP M V T+ F C G L G C G WS
Sbjct: 357 TEEVPSCQVVKCSSLAVPGKINMSCSGEPVFGTVCKFACPEGWTLNGSAARTCGATGHWS 416
Query: 636 GDSPTCE 642
G PTCE
Sbjct: 417 GLLPTCE 423
Score = 124 bits (300), Expect = 1e-27
Identities = 70/237 (29%), Positives = 105/237 (44%), Gaps = 11/237 (4%)
Query: 494 SYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTIHKGSFVLIN----GTTTYG 549
++ CE G L G+ S+ CT G W P+CK V C + V + G T+
Sbjct: 207 TFDCEEGFELMGAQSLQCTSSGNWDNEKPTCKAVTCRAVRQPQNGSVRCSHSPAGEFTFK 266
Query: 550 SIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAF-----DY 604
S FTCE + L G ++ C G+W+ IP CE C P G + ++
Sbjct: 267 SSCNFTCEEGFMLQGPAQVECTTQGQWTQQIPVCEAVRCDAVHQPPKGLVRCAHSPIGEF 326
Query: 605 YVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTT 664
S+ F CE G +L G L C G+W+ + P+C+ + C L +P +G
Sbjct: 327 TYKSSCAFSCEEGFELHGSTQLECTSQGQWTEEVPSCQVVKCSSL-AVPGKINMSCSGEP 385
Query: 665 HLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSD-PIVAEKSIVSVT 720
G+V +++C + L G RTC WS P CE S+ P+VA S ++
Sbjct: 386 VFGTVCKFACPEGWTLNGSAARTCGATGHWSGLLPTCEAPTESNIPLVAGLSAAGLS 442
Score = 118 bits (285), Expect = 9e-26
Identities = 76/294 (25%), Positives = 120/294 (40%), Gaps = 32/294 (10%)
Query: 499 NGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTIHKGSFVLI---NGTTTYGSIAQFT 555
+G + + TC +SG+ + V C T FV G+ + + F
Sbjct: 151 HGECVETINNYTCKCDPGFSGLKCE-QMVECDAVTNPANGFVECFQNPGSFPWNTTCTFD 209
Query: 556 CEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGG-----YMEAFDYYVHSTI 610
CE + L GA+ L C G W + P+C+ +C P G + A ++ S+
Sbjct: 210 CEEGFELMGAQSLQCTSSGNWDNEKPTCKAVTCRAVRQPQNGSVRCSHSPAGEFTFKSSC 269
Query: 611 NFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLN---GTTHLG 667
NF CE G L G + C G+W+ P CE + C + P G + + G
Sbjct: 270 NFTCEEGFMLQGPAQVECTTQGQWTQQIPVCEAVRCDAVHQPPKGLVRCAHSPIGEFTYK 329
Query: 668 SVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHG 727
S +SC + L G + CT + QW++ P C+ ++CS V K +S +G
Sbjct: 330 SSCAFSCEEGFELHGSTQLECTSQGQWTEEVPSCQVVKCSSLAVPGKINMSCSGEP---- 385
Query: 728 HTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQ 781
G + K+ C +G+ + G + TC G WSG PTC+
Sbjct: 386 ----------------VFGTVCKFACPEGWTLNGSAARTCGATGHWSGLLPTCE 423
Score = 112 bits (269), Expect = 8e-24
Identities = 67/229 (29%), Positives = 105/229 (45%), Gaps = 15/229 (6%)
Query: 751 YRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTL---PSNATFYGA 807
+ CE+G++++G C +G W PTC+ V C + +NG V P+ + +
Sbjct: 208 FDCEEGFELMGAQSLQCTSSGNWDNEKPTCKAVTCRAVRQPQNGSVRCSHSPAGEFTFKS 267
Query: 808 TAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSI 867
+ + C+E + L+G + C G W+ + P+C+ + C D Q G LV + I
Sbjct: 268 SCNFTCEEGFMLQGPAQVECTTQGQWTQQIPVCEAVRC-DAVHQPPKG---LVRCAHSPI 323
Query: 868 G-----GEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVIS- 921
G + CE G+ L G C S+GQW VP C + C S GKI +S
Sbjct: 324 GEFTYKSSCAFSCEEGFELHGSTQLECTSQGQWTEEVPSCQVVKCSSLA--VPGKINMSC 381
Query: 922 NGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCELATNEAV 970
+G +FG+ ++ C + G R C G WSG P+CE T +
Sbjct: 382 SGEPVFGTVCKFACPEGWTLNGSAARTCGATGHWSGLLPTCEAPTESNI 430
Score = 86.6 bits (205), Expect = 4e-16
Identities = 56/206 (27%), Positives = 90/206 (43%), Gaps = 9/206 (4%)
Query: 766 TCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSN-ATF-YGATAFYQCDENWELEGVI 823
TC+ + +SG Q V+C NG V N +F + T + C+E +EL G
Sbjct: 162 TCKCDPGFSGLKCE-QMVECDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMGAQ 220
Query: 824 RRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLL--VVTSTLSIGGEAHYQCERGYNL 881
C +G W E P CK +TC Q + GS + ++ CE G+ L
Sbjct: 221 SLQCTSSGNWDNEKPTCKAVTC-RAVRQPQNGSVRCSHSPAGEFTFKSSCNFTCEEGFML 279
Query: 882 KGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISN---GSTLFGSSVEYYCLSQ 938
+G C ++GQW +PVC + C + G + ++ G + SS + C
Sbjct: 280 QGPAQVECTTQGQWTQQIPVCEAVRCDAVHQPPKGLVRCAHSPIGEFTYKSSCAFSCEEG 339
Query: 939 YQRVGPFLRKCLDDGRWSGEEPSCEL 964
++ G +C G+W+ E PSC++
Sbjct: 340 FELHGSTQLECTSQGQWTEEVPSCQV 365
Score = 46.4 bits (105), Expect = 6e-04
Identities = 26/73 (35%), Positives = 35/73 (47%), Gaps = 3/73 (4%)
Query: 2 CGHPAVPPNARVS-IPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCG- 59
C P N V N + T ++C+EG+EL GA+ +CT G+W E P C
Sbjct: 180 CDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGNWDNEKPTCKA 239
Query: 60 -TNVAFRKPANQS 71
T A R+P N S
Sbjct: 240 VTCRAVRQPQNGS 252
Score = 44.0 bits (99), Expect = 0.003
Identities = 16/30 (53%), Positives = 21/30 (70%)
Query: 29 YECDEGYELFGARQRECTLRGDWTLEPPFC 58
+ C+EG+EL G+ Q ECT +G WT E P C
Sbjct: 334 FSCEEGFELHGSTQLECTSQGQWTEEVPSC 363
Score = 38.3 bits (85), Expect = 0.15
Identities = 14/30 (46%), Positives = 19/30 (63%)
Query: 29 YECDEGYELFGARQRECTLRGDWTLEPPFC 58
+ C+EG+ L G Q ECT +G WT + P C
Sbjct: 271 FTCEEGFMLQGPAQVECTTQGQWTQQIPVC 300
Score = 38.3 bits (85), Expect = 0.15
Identities = 20/58 (34%), Positives = 27/58 (46%), Gaps = 2/58 (3%)
Query: 1 RCGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
+C AVP +S E V GT+ + C EG+ L G+ R C G W+ P C
Sbjct: 367 KCSSLAVPGKINMSCSGEP--VFGTVCKFACPEGWTLNGSAARTCGATGHWSGLLPTC 422
Score = 35.1 bits (77), Expect = 1.4
Identities = 17/68 (25%), Positives = 33/68 (48%), Gaps = 2/68 (2%)
Query: 905 IDCRSPGNIENGKIVI--SNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
++C + N NG + + GS + ++ + C ++ +G +C G W E+P+C
Sbjct: 178 VECDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGNWDNEKPTC 237
Query: 963 ELATNEAV 970
+ T AV
Sbjct: 238 KAVTCRAV 245
>M14057-1|AAA88042.1| 660|Homo sapiens F13A1 protein.
Length = 660
Score = 128 bits (309), Expect = 1e-28
Identities = 149/543 (27%), Positives = 221/543 (40%), Gaps = 67/543 (12%)
Query: 450 ERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNG--HKAGSLASYTCENGHILSGST 507
+ TC EG W E PRC F C P +SN ++ +K Y C +G+ +G
Sbjct: 72 QTTCTTEG-WSPE-PRC-FKKCTKPD-LSNGYISDVKLLYKIQENMHYGCASGYKTTGGK 127
Query: 508 S--VTCTLGGAWSGVPPSCK-YVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNG 564
V L WS P K + C P ++ G++ T Q+ C Y+ G
Sbjct: 128 DEEVVQCLSDGWSSQPTCRKEHETCLAPELYNGNYSTTQKTFKVKDKVQYECATGYYTAG 187
Query: 565 A---EELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFD--YYVHSTINFHCEAGHK 619
EE+ C G WS P C C + GY Y + F C +
Sbjct: 188 GKKTEEVECLTYG-WSLT-PKCTKLKCSSLRLIENGYFHPVKQTYEEGDVVQFFCHENYY 245
Query: 620 LIGEPNLVCQQDGEWSGDSPTCE--YIDCGKLPTLPYGTMELLNGTTHL-GSVIQYSCTT 676
L G + C G W +SP CE C P LP + + TT+ G ++ C
Sbjct: 246 LSGSDLIQCYNFG-WYPESPVCEGRRNRCPP-PPLPINSKIQTHSTTYRHGEIVHIECEL 303
Query: 677 NYRLVGPVRRTCTEEFQWSDSSPRC----EEIRCSDPIVAEKSIVSVTGNDRSHGHTLIR 732
N+ + G C E+ +W++ P+C E++ C +P E N ++ H+ I
Sbjct: 304 NFEIHGSAEIRC-EDGKWTEP-PKCIEGQEKVACEEPPFIE--------NGAANLHSKI- 352
Query: 733 TSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTC--QYVDCGNPGR 790
Y G V Y C+ GY + G + TC + G+W+ P C +C +P
Sbjct: 353 ----------YYNGDKVTYACKSGYLLHGSNEITC-NRGKWT-LPPECVENNENCKHPPV 400
Query: 791 IENGKVT---LPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPD 847
+ NG V L S AT G++ Y+C+E + L G C E G WS PP+C E +
Sbjct: 401 VMNGAVADGILASYAT--GSSVEYRCNEYYLLRGSKISRC-EQGKWS-SPPVCLEPCTVN 456
Query: 848 PSAQIKAGSGLLVVTSTLSIGGEA-HYQCERGYNLKGHQTRTCISKGQWNGTV--PVCIP 904
+ + + G+ + C++GY+L + +S G V P+C
Sbjct: 457 VDYMNRNNIEMKWKYEGKVLHGDLIDFVCKQGYDLSPLTPLSELSVQCNRGEVKYPLCTR 516
Query: 905 ID----CRSPGNIENGKIVISNGSTLF-GSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEE 959
+ C SP I++G I+ S T GSSVEY C + G CL DG W+
Sbjct: 517 KESKGMCTSPPLIKHGVIISSTVDTYENGSSVEYRCFDHHFLEGSREAYCL-DGMWT-TP 574
Query: 960 PSC 962
P C
Sbjct: 575 PLC 577
Score = 125 bits (301), Expect = 1e-27
Identities = 119/415 (28%), Positives = 179/415 (43%), Gaps = 54/415 (13%)
Query: 566 EELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFD--YYVHSTINFHCEAGHKLIG- 622
E+ C +G WS + P C C +P++ S GY+ Y + +++ C +G+K G
Sbjct: 71 EQTTCTTEG-WSPE-PRC-FKKCTKPDL-SNGYISDVKLLYKIQENMHYGCASGYKTTGG 126
Query: 623 --EPNLVCQQDGEWSGDSPTC--EYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNY 678
E + C DG WS PTC E+ C P L G T + +QY C T Y
Sbjct: 127 KDEEVVQCLSDG-WSSQ-PTCRKEHETC-LAPELYNGNYSTTQKTFKVKDKVQYECATGY 183
Query: 679 RLVGPVRRTCTE--EFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDN 736
G + E + WS +P+C +++CS + E N H
Sbjct: 184 YTAGGKKTEEVECLTYGWS-LTPKCTKLKCSSLRLIE--------NGYFH---------- 224
Query: 737 RDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQ--YVDCGNPGRIENG 794
V TY G +V++ C + Y + G L C + G W +P C+ C P N
Sbjct: 225 -PVKQTYEEGDVVQFFCHENYYLSGSDLIQCYNFG-WYPESPVCEGRRNRCPPPPLPINS 282
Query: 795 KVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKE----ITCPDPSA 850
K+ S +G +C+ N+E+ G C E+G W+ EPP C E + C +P
Sbjct: 283 KIQTHSTTYRHGEIVHIECELNFEIHGSAEIRC-EDGKWT-EPPKCIEGQEKVACEEPPF 340
Query: 851 QIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPID--CR 908
I+ G+ L + G + Y C+ GY L G TC ++G+W P C+ + C+
Sbjct: 341 -IENGAANLH-SKIYYNGDKVTYACKSGYLLHGSNEITC-NRGKWT-LPPECVENNENCK 396
Query: 909 SPGNIENGKIVISN-GSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
P + NG + S GSSVEY C Y G + +C + G+WS P C
Sbjct: 397 HPPVVMNGAVADGILASYATGSSVEYRCNEYYLLRGSKISRC-EQGKWS-SPPVC 449
Score = 118 bits (285), Expect = 9e-26
Identities = 124/531 (23%), Positives = 209/531 (39%), Gaps = 62/531 (11%)
Query: 437 YSCRENFTLVGNPERT---CGDEGIWDGEAPRCL--FDWCPDPPAVS-NASVTVNGHKAG 490
Y C + G + C +G W + P C + C P + N S T K
Sbjct: 115 YGCASGYKTTGGKDEEVVQCLSDG-WSSQ-PTCRKEHETCLAPELYNGNYSTTQKTFKVK 172
Query: 491 SLASYTCENGHILSG---STSVTCTLGGAWSGVPPSCKYVNCGT-PTIHKGSFVLINGTT 546
Y C G+ +G + V C G WS + P C + C + I G F + T
Sbjct: 173 DKVQYECATGYYTAGGKKTEEVECLTYG-WS-LTPKCTKLKCSSLRLIENGYFHPVKQTY 230
Query: 547 TYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCE--LTSCPEPEVPSGGYMEAFD- 603
G + QF C +Y+L+G++ + C G W + P CE CP P +P ++
Sbjct: 231 EEGDVVQFFCHENYYLSGSDLIQCYNFG-WYPESPVCEGRRNRCPPPPLPINSKIQTHST 289
Query: 604 YYVHSTI-NFHCEAGHKLIGEPNLVCQQDGEWSGDSPTC----EYIDCGKLPTLPYGTME 658
Y H I + CE ++ G + C +DG+W+ + P C E + C + P + G
Sbjct: 290 TYRHGEIVHIECELNFEIHGSAEIRC-EDGKWT-EPPKCIEGQEKVACEEPPFIENGAAN 347
Query: 659 LLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVS 718
L + + G + Y+C + Y L G TC +W+ P C E
Sbjct: 348 LHSKIYYNGDKVTYACKSGYLLHGSNEITCNRG-KWT-LPPECVE--------------- 390
Query: 719 VTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTP 778
+ H ++ + + +Y G+ V+YRC + Y + G +S CE G+WS + P
Sbjct: 391 -NNENCKHPPVVMNGAVADGILASYATGSSVEYRCNEYYLLRGSKISRCE-QGKWS-SPP 447
Query: 779 TCQYVDCGNPGRIENGKVTLP---SNATFYGATAFYQCDENWELEGV--IRRMCQENGTW 833
C N + + + +G + C + ++L + + + +
Sbjct: 448 VCLEPCTVNVDYMNRNNIEMKWKYEGKVLHGDLIDFVCKQGYDLSPLTPLSELSVQCNRG 507
Query: 834 SLEPPIC--KEI--TCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTC 889
++ P+C KE C P IK G + T G Y+C + L+G + C
Sbjct: 508 EVKYPLCTRKESKGMCTSPPL-IKHGVIISSTVDTYENGSSVEYRCFDHHFLEGSREAYC 566
Query: 890 ISKGQWNGTVPVCIPIDCRSPGNIENGKIVI-----SNGSTLFGSSVEYYC 935
+ G W T P+C+ S +E +++ + L G +E+ C
Sbjct: 567 LD-GMWT-TPPLCLEPCTLSFTEMEKNNLLLKWDFDNRPHILHGEYIEFIC 615
Score = 112 bits (269), Expect = 8e-24
Identities = 117/456 (25%), Positives = 182/456 (39%), Gaps = 44/456 (9%)
Query: 346 CQYLPPTCGSPDKLL-NTTILGNDYDVGSRIVYKCPEGHMLLGDKSRH---CKKDGFWSG 401
C+ TC +P+ N + + V ++ Y+C G+ G K C G WS
Sbjct: 145 CRKEHETCLAPELYNGNYSTTQKTFKVKDKVQYECATGYYTAGGKKTEEVECLTYG-WS- 202
Query: 402 APPSCKYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDG 461
P C + C L IE+G + G + C EN+ L G+ C + G W
Sbjct: 203 LTPKCTKLKCSSLRLIENGYFHPVKQTYEEGDVVQFFCHENYYLSGSDLIQCYNFG-WYP 261
Query: 462 EAPRC--LFDWCPDPPAVSNASVTVNG--HKAGSLASYTCENGHILSGSTSVTCTLGGAW 517
E+P C + CP PP N+ + + ++ G + CE + GS + C G W
Sbjct: 262 ESPVCEGRRNRCPPPPLPINSKIQTHSTTYRHGEIVHIECELNFEIHGSAEIRCE-DGKW 320
Query: 518 SGVPPSC----KYVNCGTPT-IHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNR 572
+ PP C + V C P I G+ L + G + C+ Y L+G+ E+ CNR
Sbjct: 321 T-EPPKCIEGQEKVACEEPPFIENGAANLHSKIYYNGDKVTYACKSGYLLHGSNEITCNR 379
Query: 573 DGKWSYDIPSC--ELTSCPEPEVPSGGYME---AFDYYVHSTINFHCEAGHKLIGEPNLV 627
GKW+ P C +C P V G + Y S++ + C + L G
Sbjct: 380 -GKWTLP-PECVENNENCKHPPVVMNGAVADGILASYATGSSVEYRCNEYYLLRGSKISR 437
Query: 628 CQQDGEWSGDSPTCEYIDCGKLPTLPYGTMEL---LNGTTHLGSVIQYSCTTNYRLVGPV 684
C+Q G+WS P C + + +E+ G G +I + C Y L P+
Sbjct: 438 CEQ-GKWS-SPPVCLEPCTVNVDYMNRNNIEMKWKYEGKVLHGDLIDFVCKQGYDL-SPL 494
Query: 685 RRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYR 744
S+ S +C P+ K + + H +I +S +TY
Sbjct: 495 T-------PLSELSVQCNRGEVKYPLCTRKESKGMCTSPPLIKHGVIISS----TVDTYE 543
Query: 745 IGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTC 780
G+ V+YRC + + G + C D G W+ T P C
Sbjct: 544 NGSSVEYRCFDHHFLEGSREAYCLD-GMWT-TPPLC 577
Score = 35.9 bits (79), Expect = 0.79
Identities = 22/59 (37%), Positives = 26/59 (44%), Gaps = 5/59 (8%)
Query: 24 GTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTNVAFRKPANQSTTVRGGAAANG 82
G Y C GY L G+ + C RG WTL PP C N + V GA A+G
Sbjct: 356 GDKVTYACKSGYLLHGSNEITCN-RGKWTL-PPECVEN---NENCKHPPVVMNGAVADG 409
Score = 35.1 bits (77), Expect = 1.4
Identities = 19/57 (33%), Positives = 27/57 (47%), Gaps = 2/57 (3%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C HP V N V+ + G+ Y C+E Y L G++ C +G W+ PP C
Sbjct: 395 CKHPPVVMNGAVADGILASYATGSSVEYRCNEYYLLRGSKISRCE-QGKWS-SPPVC 449
>AY692223-1|AAT85802.1| 661|Homo sapiens coagulation factor XIII, B
polypeptide protein.
Length = 661
Score = 128 bits (309), Expect = 1e-28
Identities = 149/543 (27%), Positives = 221/543 (40%), Gaps = 67/543 (12%)
Query: 450 ERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNG--HKAGSLASYTCENGHILSGST 507
+ TC EG W E PRC F C P +SN ++ +K Y C +G+ +G
Sbjct: 73 QTTCTTEG-WSPE-PRC-FKKCTKPD-LSNGYISDVKLLYKIQENMHYGCASGYKTTGGK 128
Query: 508 S--VTCTLGGAWSGVPPSCK-YVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNG 564
V L WS P K + C P ++ G++ T Q+ C Y+ G
Sbjct: 129 DEEVVQCLSDGWSSQPTCRKEHETCLAPELYNGNYSTTQKTFKVKDKVQYECATGYYTAG 188
Query: 565 A---EELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFD--YYVHSTINFHCEAGHK 619
EE+ C G WS P C C + GY Y + F C +
Sbjct: 189 GKKTEEVECLTYG-WSLT-PKCTKLKCSSLRLIENGYFHPVKQTYEEGDVVQFFCHENYY 246
Query: 620 LIGEPNLVCQQDGEWSGDSPTCE--YIDCGKLPTLPYGTMELLNGTTHL-GSVIQYSCTT 676
L G + C G W +SP CE C P LP + + TT+ G ++ C
Sbjct: 247 LSGSDLIQCYNFG-WYPESPVCEGRRNRCPP-PPLPINSKIQTHSTTYRHGEIVHIECEL 304
Query: 677 NYRLVGPVRRTCTEEFQWSDSSPRC----EEIRCSDPIVAEKSIVSVTGNDRSHGHTLIR 732
N+ + G C E+ +W++ P+C E++ C +P E N ++ H+ I
Sbjct: 305 NFEIHGSAEIRC-EDGKWTEP-PKCIEGQEKVACEEPPFIE--------NGAANLHSKI- 353
Query: 733 TSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTC--QYVDCGNPGR 790
Y G V Y C+ GY + G + TC + G+W+ P C +C +P
Sbjct: 354 ----------YYNGDKVTYACKSGYLLHGSNEITC-NRGKWT-LPPECVENNENCKHPPV 401
Query: 791 IENGKVT---LPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPD 847
+ NG V L S AT G++ Y+C+E + L G C E G WS PP+C E +
Sbjct: 402 VMNGAVADGILASYAT--GSSVEYRCNEYYLLRGSKISRC-EQGKWS-SPPVCLEPCTVN 457
Query: 848 PSAQIKAGSGLLVVTSTLSIGGEA-HYQCERGYNLKGHQTRTCISKGQWNGTV--PVCIP 904
+ + + G+ + C++GY+L + +S G V P+C
Sbjct: 458 VDYMNRNNIEMKWKYEGKVLHGDLIDFVCKQGYDLSPLTPLSELSVQCNRGEVKYPLCTR 517
Query: 905 ID----CRSPGNIENGKIVISNGSTLF-GSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEE 959
+ C SP I++G I+ S T GSSVEY C + G CL DG W+
Sbjct: 518 KESKGMCTSPPLIKHGVIISSTVDTYENGSSVEYRCFDHHFLEGSREAYCL-DGMWT-TP 575
Query: 960 PSC 962
P C
Sbjct: 576 PLC 578
Score = 125 bits (301), Expect = 1e-27
Identities = 119/415 (28%), Positives = 179/415 (43%), Gaps = 54/415 (13%)
Query: 566 EELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFD--YYVHSTINFHCEAGHKLIG- 622
E+ C +G WS + P C C +P++ S GY+ Y + +++ C +G+K G
Sbjct: 72 EQTTCTTEG-WSPE-PRC-FKKCTKPDL-SNGYISDVKLLYKIQENMHYGCASGYKTTGG 127
Query: 623 --EPNLVCQQDGEWSGDSPTC--EYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNY 678
E + C DG WS PTC E+ C P L G T + +QY C T Y
Sbjct: 128 KDEEVVQCLSDG-WSSQ-PTCRKEHETC-LAPELYNGNYSTTQKTFKVKDKVQYECATGY 184
Query: 679 RLVGPVRRTCTE--EFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDN 736
G + E + WS +P+C +++CS + E N H
Sbjct: 185 YTAGGKKTEEVECLTYGWS-LTPKCTKLKCSSLRLIE--------NGYFH---------- 225
Query: 737 RDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQ--YVDCGNPGRIENG 794
V TY G +V++ C + Y + G L C + G W +P C+ C P N
Sbjct: 226 -PVKQTYEEGDVVQFFCHENYYLSGSDLIQCYNFG-WYPESPVCEGRRNRCPPPPLPINS 283
Query: 795 KVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKE----ITCPDPSA 850
K+ S +G +C+ N+E+ G C E+G W+ EPP C E + C +P
Sbjct: 284 KIQTHSTTYRHGEIVHIECELNFEIHGSAEIRC-EDGKWT-EPPKCIEGQEKVACEEPPF 341
Query: 851 QIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPID--CR 908
I+ G+ L + G + Y C+ GY L G TC ++G+W P C+ + C+
Sbjct: 342 -IENGAANLH-SKIYYNGDKVTYACKSGYLLHGSNEITC-NRGKWT-LPPECVENNENCK 397
Query: 909 SPGNIENGKIVISN-GSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
P + NG + S GSSVEY C Y G + +C + G+WS P C
Sbjct: 398 HPPVVMNGAVADGILASYATGSSVEYRCNEYYLLRGSKISRC-EQGKWS-SPPVC 450
Score = 118 bits (285), Expect = 9e-26
Identities = 124/531 (23%), Positives = 209/531 (39%), Gaps = 62/531 (11%)
Query: 437 YSCRENFTLVGNPERT---CGDEGIWDGEAPRCL--FDWCPDPPAVS-NASVTVNGHKAG 490
Y C + G + C +G W + P C + C P + N S T K
Sbjct: 116 YGCASGYKTTGGKDEEVVQCLSDG-WSSQ-PTCRKEHETCLAPELYNGNYSTTQKTFKVK 173
Query: 491 SLASYTCENGHILSG---STSVTCTLGGAWSGVPPSCKYVNCGT-PTIHKGSFVLINGTT 546
Y C G+ +G + V C G WS + P C + C + I G F + T
Sbjct: 174 DKVQYECATGYYTAGGKKTEEVECLTYG-WS-LTPKCTKLKCSSLRLIENGYFHPVKQTY 231
Query: 547 TYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCE--LTSCPEPEVPSGGYMEAFD- 603
G + QF C +Y+L+G++ + C G W + P CE CP P +P ++
Sbjct: 232 EEGDVVQFFCHENYYLSGSDLIQCYNFG-WYPESPVCEGRRNRCPPPPLPINSKIQTHST 290
Query: 604 YYVHSTI-NFHCEAGHKLIGEPNLVCQQDGEWSGDSPTC----EYIDCGKLPTLPYGTME 658
Y H I + CE ++ G + C +DG+W+ + P C E + C + P + G
Sbjct: 291 TYRHGEIVHIECELNFEIHGSAEIRC-EDGKWT-EPPKCIEGQEKVACEEPPFIENGAAN 348
Query: 659 LLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVS 718
L + + G + Y+C + Y L G TC +W+ P C E
Sbjct: 349 LHSKIYYNGDKVTYACKSGYLLHGSNEITCNRG-KWT-LPPECVE--------------- 391
Query: 719 VTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTP 778
+ H ++ + + +Y G+ V+YRC + Y + G +S CE G+WS + P
Sbjct: 392 -NNENCKHPPVVMNGAVADGILASYATGSSVEYRCNEYYLLRGSKISRCE-QGKWS-SPP 448
Query: 779 TCQYVDCGNPGRIENGKVTLP---SNATFYGATAFYQCDENWELEGV--IRRMCQENGTW 833
C N + + + +G + C + ++L + + + +
Sbjct: 449 VCLEPCTVNVDYMNRNNIEMKWKYEGKVLHGDLIDFVCKQGYDLSPLTPLSELSVQCNRG 508
Query: 834 SLEPPIC--KEI--TCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTC 889
++ P+C KE C P IK G + T G Y+C + L+G + C
Sbjct: 509 EVKYPLCTRKESKGMCTSPPL-IKHGVIISSTVDTYENGSSVEYRCFDHHFLEGSREAYC 567
Query: 890 ISKGQWNGTVPVCIPIDCRSPGNIENGKIVI-----SNGSTLFGSSVEYYC 935
+ G W T P+C+ S +E +++ + L G +E+ C
Sbjct: 568 LD-GMWT-TPPLCLEPCTLSFTEMEKNNLLLKWDFDNRPHILHGEYIEFIC 616
Score = 112 bits (269), Expect = 8e-24
Identities = 117/456 (25%), Positives = 182/456 (39%), Gaps = 44/456 (9%)
Query: 346 CQYLPPTCGSPDKLL-NTTILGNDYDVGSRIVYKCPEGHMLLGDKSRH---CKKDGFWSG 401
C+ TC +P+ N + + V ++ Y+C G+ G K C G WS
Sbjct: 146 CRKEHETCLAPELYNGNYSTTQKTFKVKDKVQYECATGYYTAGGKKTEEVECLTYG-WS- 203
Query: 402 APPSCKYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDG 461
P C + C L IE+G + G + C EN+ L G+ C + G W
Sbjct: 204 LTPKCTKLKCSSLRLIENGYFHPVKQTYEEGDVVQFFCHENYYLSGSDLIQCYNFG-WYP 262
Query: 462 EAPRC--LFDWCPDPPAVSNASVTVNG--HKAGSLASYTCENGHILSGSTSVTCTLGGAW 517
E+P C + CP PP N+ + + ++ G + CE + GS + C G W
Sbjct: 263 ESPVCEGRRNRCPPPPLPINSKIQTHSTTYRHGEIVHIECELNFEIHGSAEIRCE-DGKW 321
Query: 518 SGVPPSC----KYVNCGTPT-IHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNR 572
+ PP C + V C P I G+ L + G + C+ Y L+G+ E+ CNR
Sbjct: 322 T-EPPKCIEGQEKVACEEPPFIENGAANLHSKIYYNGDKVTYACKSGYLLHGSNEITCNR 380
Query: 573 DGKWSYDIPSC--ELTSCPEPEVPSGGYME---AFDYYVHSTINFHCEAGHKLIGEPNLV 627
GKW+ P C +C P V G + Y S++ + C + L G
Sbjct: 381 -GKWTLP-PECVENNENCKHPPVVMNGAVADGILASYATGSSVEYRCNEYYLLRGSKISR 438
Query: 628 CQQDGEWSGDSPTCEYIDCGKLPTLPYGTMEL---LNGTTHLGSVIQYSCTTNYRLVGPV 684
C+Q G+WS P C + + +E+ G G +I + C Y L P+
Sbjct: 439 CEQ-GKWS-SPPVCLEPCTVNVDYMNRNNIEMKWKYEGKVLHGDLIDFVCKQGYDL-SPL 495
Query: 685 RRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYR 744
S+ S +C P+ K + + H +I +S +TY
Sbjct: 496 T-------PLSELSVQCNRGEVKYPLCTRKESKGMCTSPPLIKHGVIISS----TVDTYE 544
Query: 745 IGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTC 780
G+ V+YRC + + G + C D G W+ T P C
Sbjct: 545 NGSSVEYRCFDHHFLEGSREAYCLD-GMWT-TPPLC 578
Score = 35.9 bits (79), Expect = 0.79
Identities = 22/59 (37%), Positives = 26/59 (44%), Gaps = 5/59 (8%)
Query: 24 GTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTNVAFRKPANQSTTVRGGAAANG 82
G Y C GY L G+ + C RG WTL PP C N + V GA A+G
Sbjct: 357 GDKVTYACKSGYLLHGSNEITCN-RGKWTL-PPECVEN---NENCKHPPVVMNGAVADG 410
Score = 35.1 bits (77), Expect = 1.4
Identities = 19/57 (33%), Positives = 27/57 (47%), Gaps = 2/57 (3%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C HP V N V+ + G+ Y C+E Y L G++ C +G W+ PP C
Sbjct: 396 CKHPPVVMNGAVADGILASYATGSSVEYRCNEYYLLRGSKISRCE-QGKWS-SPPVC 450
>AL353809-2|CAH72549.1| 661|Homo sapiens coagulation factor XIII, B
polypeptide protein.
Length = 661
Score = 128 bits (309), Expect = 1e-28
Identities = 149/543 (27%), Positives = 221/543 (40%), Gaps = 67/543 (12%)
Query: 450 ERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNG--HKAGSLASYTCENGHILSGST 507
+ TC EG W E PRC F C P +SN ++ +K Y C +G+ +G
Sbjct: 73 QTTCTTEG-WSPE-PRC-FKKCTKPD-LSNGYISDVKLLYKIQENMRYGCASGYKTTGGK 128
Query: 508 S--VTCTLGGAWSGVPPSCK-YVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNG 564
V L WS P K + C P ++ G++ T Q+ C Y+ G
Sbjct: 129 DEEVVQCLSDGWSSQPTCRKEHETCLAPELYNGNYSTTQKTFKVKDKVQYECATGYYTAG 188
Query: 565 A---EELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFD--YYVHSTINFHCEAGHK 619
EE+ C G WS P C C + GY Y + F C +
Sbjct: 189 GKKTEEVECLTYG-WSLT-PKCTKLKCSSLRLIENGYFHPVKQTYEEGDVVQFFCHENYY 246
Query: 620 LIGEPNLVCQQDGEWSGDSPTCE--YIDCGKLPTLPYGTMELLNGTTHL-GSVIQYSCTT 676
L G + C G W +SP CE C P LP + + TT+ G ++ C
Sbjct: 247 LSGSDLIQCYNFG-WYPESPVCEGRRNRCPP-PPLPINSKIQTHSTTYRHGEIVHIECEL 304
Query: 677 NYRLVGPVRRTCTEEFQWSDSSPRC----EEIRCSDPIVAEKSIVSVTGNDRSHGHTLIR 732
N+ + G C E+ +W++ P+C E++ C +P E N ++ H+ I
Sbjct: 305 NFEIHGSAEIRC-EDGKWTEP-PKCIEGQEKVACEEPPFIE--------NGAANLHSKI- 353
Query: 733 TSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTC--QYVDCGNPGR 790
Y G V Y C+ GY + G + TC + G+W+ P C +C +P
Sbjct: 354 ----------YYNGDKVTYACKSGYLLHGSNEITC-NRGKWT-LPPECVENNENCKHPPV 401
Query: 791 IENGKVT---LPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPD 847
+ NG V L S AT G++ Y+C+E + L G C E G WS PP+C E +
Sbjct: 402 VMNGAVADGILASYAT--GSSVEYRCNEYYLLRGSKISRC-EQGKWS-SPPVCLEPCTVN 457
Query: 848 PSAQIKAGSGLLVVTSTLSIGGEA-HYQCERGYNLKGHQTRTCISKGQWNGTV--PVCIP 904
+ + + G+ + C++GY+L + +S G V P+C
Sbjct: 458 VDYMNRNNIEMKWKYEGKVLHGDLIDFVCKQGYDLSPLTPLSELSVQCNRGEVKYPLCTR 517
Query: 905 ID----CRSPGNIENGKIVISNGSTLF-GSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEE 959
+ C SP I++G I+ S T GSSVEY C + G CL DG W+
Sbjct: 518 KESKGMCTSPPLIKHGVIISSTVDTYENGSSVEYRCFDHHFLEGSREAYCL-DGMWT-TP 575
Query: 960 PSC 962
P C
Sbjct: 576 PLC 578
Score = 124 bits (300), Expect = 1e-27
Identities = 119/415 (28%), Positives = 178/415 (42%), Gaps = 54/415 (13%)
Query: 566 EELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFD--YYVHSTINFHCEAGHKLIG- 622
E+ C +G WS + P C C +P++ S GY+ Y + + + C +G+K G
Sbjct: 72 EQTTCTTEG-WSPE-PRC-FKKCTKPDL-SNGYISDVKLLYKIQENMRYGCASGYKTTGG 127
Query: 623 --EPNLVCQQDGEWSGDSPTC--EYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNY 678
E + C DG WS PTC E+ C P L G T + +QY C T Y
Sbjct: 128 KDEEVVQCLSDG-WSSQ-PTCRKEHETC-LAPELYNGNYSTTQKTFKVKDKVQYECATGY 184
Query: 679 RLVGPVRRTCTE--EFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDN 736
G + E + WS +P+C +++CS + E N H
Sbjct: 185 YTAGGKKTEEVECLTYGWS-LTPKCTKLKCSSLRLIE--------NGYFH---------- 225
Query: 737 RDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQ--YVDCGNPGRIENG 794
V TY G +V++ C + Y + G L C + G W +P C+ C P N
Sbjct: 226 -PVKQTYEEGDVVQFFCHENYYLSGSDLIQCYNFG-WYPESPVCEGRRNRCPPPPLPINS 283
Query: 795 KVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKE----ITCPDPSA 850
K+ S +G +C+ N+E+ G C E+G W+ EPP C E + C +P
Sbjct: 284 KIQTHSTTYRHGEIVHIECELNFEIHGSAEIRC-EDGKWT-EPPKCIEGQEKVACEEPPF 341
Query: 851 QIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPID--CR 908
I+ G+ L + G + Y C+ GY L G TC ++G+W P C+ + C+
Sbjct: 342 -IENGAANLH-SKIYYNGDKVTYACKSGYLLHGSNEITC-NRGKWT-LPPECVENNENCK 397
Query: 909 SPGNIENGKIVISN-GSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
P + NG + S GSSVEY C Y G + +C + G+WS P C
Sbjct: 398 HPPVVMNGAVADGILASYATGSSVEYRCNEYYLLRGSKISRC-EQGKWS-SPPVC 450
Score = 119 bits (286), Expect = 7e-26
Identities = 135/575 (23%), Positives = 224/575 (38%), Gaps = 66/575 (11%)
Query: 393 CKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERT 452
C +G WS P K L+ DV L+ + R Y C + G +
Sbjct: 76 CTTEG-WSPEPRCFKKCTKPDLSNGYISDVKLL-YKIQENMR--YGCASGYKTTGGKDEE 131
Query: 453 ---CGDEGIWDGEAPRCL--FDWCPDPPAVS-NASVTVNGHKAGSLASYTCENGHILSG- 505
C +G W + P C + C P + N S T K Y C G+ +G
Sbjct: 132 VVQCLSDG-WSSQ-PTCRKEHETCLAPELYNGNYSTTQKTFKVKDKVQYECATGYYTAGG 189
Query: 506 --STSVTCTLGGAWSGVPPSCKYVNCGT-PTIHKGSFVLINGTTTYGSIAQFTCEPDYWL 562
+ V C G WS + P C + C + I G F + T G + QF C +Y+L
Sbjct: 190 KKTEEVECLTYG-WS-LTPKCTKLKCSSLRLIENGYFHPVKQTYEEGDVVQFFCHENYYL 247
Query: 563 NGAEELVCNRDGKWSYDIPSCE--LTSCPEPEVPSGGYMEAFD-YYVHSTI-NFHCEAGH 618
+G++ + C G W + P CE CP P +P ++ Y H I + CE
Sbjct: 248 SGSDLIQCYNFG-WYPESPVCEGRRNRCPPPPLPINSKIQTHSTTYRHGEIVHIECELNF 306
Query: 619 KLIGEPNLVCQQDGEWSGDSPTC----EYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSC 674
++ G + C +DG+W+ + P C E + C + P + G L + + G + Y+C
Sbjct: 307 EIHGSAEIRC-EDGKWT-EPPKCIEGQEKVACEEPPFIENGAANLHSKIYYNGDKVTYAC 364
Query: 675 TTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTS 734
+ Y L G TC +W+ P C E + H ++ +
Sbjct: 365 KSGYLLHGSNEITCNRG-KWT-LPPECVE----------------NNENCKHPPVVMNGA 406
Query: 735 DNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENG 794
+ +Y G+ V+YRC + Y + G +S CE G+WS + P C N +
Sbjct: 407 VADGILASYATGSSVEYRCNEYYLLRGSKISRCE-QGKWS-SPPVCLEPCTVNVDYMNRN 464
Query: 795 KVTLP---SNATFYGATAFYQCDENWELEGV--IRRMCQENGTWSLEPPIC--KEI--TC 845
+ + +G + C + ++L + + + + ++ P+C KE C
Sbjct: 465 NIEMKWKYEGKVLHGDLIDFVCKQGYDLSPLTPLSELSVQCNRGEVKYPLCTRKESKGMC 524
Query: 846 PDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPI 905
P IK G + T G Y+C + L+G + C+ G W T P+C+
Sbjct: 525 TSPPL-IKHGVIISSTVDTYENGSSVEYRCFDHHFLEGSREAYCLD-GMWT-TPPLCLEP 581
Query: 906 DCRSPGNIENGKIVI-----SNGSTLFGSSVEYYC 935
S +E +++ + L G +E+ C
Sbjct: 582 CTLSFTEMEKNNLLLKWDFDNRPHILHGEYIEFIC 616
Score = 58.0 bits (134), Expect = 2e-07
Identities = 59/229 (25%), Positives = 95/229 (41%), Gaps = 29/229 (12%)
Query: 369 YDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSC--KYVNCGGLTPIEDGDVA--L 424
Y G ++ Y C G++L G C + G W+ PP C NC + +G VA +
Sbjct: 354 YYNGDKVTYACKSGYLLHGSNEITCNR-GKWT-LPPECVENNENCKHPPVVMNGAVADGI 411
Query: 425 IDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTV 484
+ + T G+ Y C E + L G+ C ++G W P CL + ++ ++ +
Sbjct: 412 LASYAT-GSSVEYRCNEYYLLRGSKISRC-EQGKW-SSPPVCLEPCTVNVDYMNRNNIEM 468
Query: 485 NGHKA-----GSLASYTCENGHILSGST-----SVTCTLGGAWSGVPPSCKYVN----CG 530
G L + C+ G+ LS T SV C G P C C
Sbjct: 469 KWKYEGKVLHGDLIDFVCKQGYDLSPLTPLSELSVQCNRGEV---KYPLCTRKESKGMCT 525
Query: 531 TPTIHKGSFVLINGTTTY--GSIAQFTCEPDYWLNGAEELVCNRDGKWS 577
+P + K ++ + TY GS ++ C ++L G+ E C DG W+
Sbjct: 526 SPPLIKHGVIISSTVDTYENGSSVEYRCFDHHFLEGSREAYC-LDGMWT 573
Score = 56.0 bits (129), Expect = 7e-07
Identities = 49/189 (25%), Positives = 80/189 (42%), Gaps = 23/189 (12%)
Query: 353 CGSPDKLLNTTILGN---DYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYV 409
C P ++N + Y GS + Y+C E ++L G K C++ G WS +PP C
Sbjct: 396 CKHPPVVMNGAVADGILASYATGSSVEYRCNEYYLLRGSKISRCEQ-GKWS-SPPVCLEP 453
Query: 410 NCGGLTPIEDGDVAL---IDNRTTHGARALYSCRENFTLVGNPERTCGDEGIW--DGEA- 463
+ + ++ + + + HG + C++ + L +P + + GE
Sbjct: 454 CTVNVDYMNRNNIEMKWKYEGKVLHGDLIDFVCKQGYDL--SPLTPLSELSVQCNRGEVK 511
Query: 464 -PRCLFD----WCPDPPAVSNA---SVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGG 515
P C C PP + + S TV+ ++ GS Y C + H L GS C L G
Sbjct: 512 YPLCTRKESKGMCTSPPLIKHGVIISSTVDTYENGSSVEYRCFDHHFLEGSREAYC-LDG 570
Query: 516 AWSGVPPSC 524
W+ PP C
Sbjct: 571 MWT-TPPLC 578
Score = 35.9 bits (79), Expect = 0.79
Identities = 22/59 (37%), Positives = 26/59 (44%), Gaps = 5/59 (8%)
Query: 24 GTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTNVAFRKPANQSTTVRGGAAANG 82
G Y C GY L G+ + C RG WTL PP C N + V GA A+G
Sbjct: 357 GDKVTYACKSGYLLHGSNEITCN-RGKWTL-PPECVEN---NENCKHPPVVMNGAVADG 410
Score = 35.1 bits (77), Expect = 1.4
Identities = 19/57 (33%), Positives = 27/57 (47%), Gaps = 2/57 (3%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C HP V N V+ + G+ Y C+E Y L G++ C +G W+ PP C
Sbjct: 396 CKHPPVVMNGAVADGILASYATGSSVEYRCNEYYLLRGSKISRCE-QGKWS-SPPVC 450
>AL021940-4|CAI19360.1| 484|Homo sapiens selectin E (endothelial
adhesion molecule 1) protein.
Length = 484
Score = 128 bits (308), Expect = 1e-28
Identities = 78/293 (26%), Positives = 127/293 (43%), Gaps = 31/293 (10%)
Query: 499 NGHILSGSTSVTCTLGGAWSGVPPSCKYVNC-GTPTIHKGSFVLIN--GTTTYGSIAQFT 555
+G + + TC +SG+ + VNC + GS V + G +Y S +
Sbjct: 151 HGECVETINNYTCKCDPGFSGLKCE-QIVNCTALESPEHGSLVCSHPLGNFSYNSSCSIS 209
Query: 556 CEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFD----YYVHSTIN 611
C+ Y + E + C G+WS IP+C + C P+ G++E F + ++T
Sbjct: 210 CDRGYLPSSMETMQCMSSGEWSAPIPACNVVECDAVTNPANGFVECFQNPGSFPWNTTCT 269
Query: 612 FHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLN---GTTHLGS 668
F CE G +L+G +L C G W + PTC+ + C + G++ + G S
Sbjct: 270 FDCEEGFELMGAQSLQCTSSGNWDNEKPTCKAVTCRAVRQPQNGSVRCSHSPAGEFTFKS 329
Query: 669 VIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGH 728
++C + L GP + CT + QW+ P CE ++CS V K +S +G
Sbjct: 330 SCNFTCEEGFMLQGPAQVECTTQGQWTQQIPVCEVVKCSSLAVPGKINMSCSGEP----- 384
Query: 729 TLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQ 781
G + K+ C +G+ + G + TC G WSG PTC+
Sbjct: 385 ---------------VFGTVCKFACPEGWTLNGSAARTCGATGHWSGLLPTCE 422
Score = 120 bits (290), Expect = 2e-26
Identities = 69/239 (28%), Positives = 104/239 (43%), Gaps = 10/239 (4%)
Query: 491 SLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTIHKGSFVLI---NGTTT 547
S S +C+ G++ S ++ C G WS P+C V C T FV G+
Sbjct: 204 SSCSISCDRGYLPSSMETMQCMSSGEWSAPIPACNVVECDAVTNPANGFVECFQNPGSFP 263
Query: 548 YGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGG-----YMEAF 602
+ + F CE + L GA+ L C G W + P+C+ +C P G + A
Sbjct: 264 WNTTCTFDCEEGFELMGAQSLQCTSSGNWDNEKPTCKAVTCRAVRQPQNGSVRCSHSPAG 323
Query: 603 DYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNG 662
++ S+ NF CE G L G + C G+W+ P CE + C L +P +G
Sbjct: 324 EFTFKSSCNFTCEEGFMLQGPAQVECTTQGQWTQQIPVCEVVKCSSL-AVPGKINMSCSG 382
Query: 663 TTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSD-PIVAEKSIVSVT 720
G+V +++C + L G RTC WS P CE S+ P+VA S ++
Sbjct: 383 EPVFGTVCKFACPEGWTLNGSAARTCGATGHWSGLLPTCEAPTESNIPLVAGLSAAGLS 441
Score = 120 bits (289), Expect = 3e-26
Identities = 66/227 (29%), Positives = 95/227 (41%), Gaps = 8/227 (3%)
Query: 365 LGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVAL 424
LGN + S C G++ ++ C G WS P+C V C +T +G V
Sbjct: 197 LGN-FSYNSSCSISCDRGYLPSSMETMQCMSSGEWSAPIPACNVVECDAVTNPANGFVEC 255
Query: 425 IDNRTTH--GARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASV 482
N + + C E F L+G C G WD E P C C N SV
Sbjct: 256 FQNPGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGNWDNEKPTCKAVTCRAVRQPQNGSV 315
Query: 483 TVNGHKAG-----SLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTIHKG 537
+ AG S ++TCE G +L G V CT G W+ P C+ V C + +
Sbjct: 316 RCSHSPAGEFTFKSSCNFTCEEGFMLQGPAQVECTTQGQWTQQIPVCEVVKCSSLAVPGK 375
Query: 538 SFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCE 584
+ +G +G++ +F C + LNG+ C G WS +P+CE
Sbjct: 376 INMSCSGEPVFGTVCKFACPEGWTLNGSAARTCGATGHWSGLLPTCE 422
Score = 113 bits (273), Expect = 2e-24
Identities = 67/223 (30%), Positives = 99/223 (44%), Gaps = 8/223 (3%)
Query: 753 CEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSN-ATF-YGATAF 810
C++GY C +G+WS P C V+C NG V N +F + T
Sbjct: 210 CDRGYLPSSMETMQCMSSGEWSAPIPACNVVECDAVTNPANGFVECFQNPGSFPWNTTCT 269
Query: 811 YQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTST--LSIG 868
+ C+E +EL G C +G W E P CK +TC Q + GS + +
Sbjct: 270 FDCEEGFELMGAQSLQCTSSGNWDNEKPTCKAVTCR-AVRQPQNGSVRCSHSPAGEFTFK 328
Query: 869 GEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVIS-NGSTLF 927
++ CE G+ L+G C ++GQW +PVC + C S GKI +S +G +F
Sbjct: 329 SSCNFTCEEGFMLQGPAQVECTTQGQWTQQIPVCEVVKCSSLA--VPGKINMSCSGEPVF 386
Query: 928 GSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCELATNEAV 970
G+ ++ C + G R C G WSG P+CE T +
Sbjct: 387 GTVCKFACPEGWTLNGSAARTCGATGHWSGLLPTCEAPTESNI 429
Score = 110 bits (264), Expect = 3e-23
Identities = 107/424 (25%), Positives = 152/424 (35%), Gaps = 50/424 (11%)
Query: 236 SFDEARKQCQSHGGDLIHGFQGATSSFLTQELERRKAQLKTQLVWIGAQKEPGLTSRTWQ 295
++DEA CQ L+ +L L WIG +K + W
Sbjct: 32 TYDEASAYCQQRYTHLVAIQNKEEIEYLNSILS-----YSPSYYWIGIRK----VNNVWV 82
Query: 296 WVDGE---LVSKPSWGKDQPNNYNGEQNCVVLDGGRG---WLWNDVGCNLDYLHWICQYL 349
WV + +W +PNN +++CV + R +WND C+ L +C
Sbjct: 83 WVGTQKPLTEEAKNWAPGEPNNRQKDEDCVEIYIKREKDVGMWNDERCSKKKLA-LCYTA 141
Query: 350 PPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYV 409
T NT+ G+ +C E + CK D +SG + V
Sbjct: 142 ACT--------NTSCSGHG---------ECVETI-----NNYTCKCDPGFSGLKCE-QIV 178
Query: 410 NCGGLTPIEDGDVALID--NRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL 467
NC L E G + ++ + SC + C G W P C
Sbjct: 179 NCTALESPEHGSLVCSHPLGNFSYNSSCSISCDRGYLPSSMETMQCMSSGEWSAPIPACN 238
Query: 468 FDWCPDPPAVSNASVTVNGHKAG----SLASYTCENGHILSGSTSVTCTLGGAWSGVPPS 523
C +N V + + ++ CE G L G+ S+ CT G W P+
Sbjct: 239 VVECDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGNWDNEKPT 298
Query: 524 CKYVNCGTPTIHKGSFVLIN----GTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYD 579
CK V C + V + G T+ S FTCE + L G ++ C G+W+
Sbjct: 299 CKAVTCRAVRQPQNGSVRCSHSPAGEFTFKSSCNFTCEEGFMLQGPAQVECTTQGQWTQQ 358
Query: 580 IPSCELTSCPEPEVPSGGYMEAFDYYVHSTI-NFHCEAGHKLIGEPNLVCQQDGEWSGDS 638
IP CE+ C VP M V T+ F C G L G C G WSG
Sbjct: 359 IPVCEVVKCSSLAVPGKINMSCSGEPVFGTVCKFACPEGWTLNGSAARTCGATGHWSGLL 418
Query: 639 PTCE 642
PTCE
Sbjct: 419 PTCE 422
Score = 94.7 bits (225), Expect = 2e-18
Identities = 74/306 (24%), Positives = 117/306 (38%), Gaps = 31/306 (10%)
Query: 605 YVHSTINFHCEAGHKLIGEP--NLVCQQDGEWSGDSPTCEYI-DCGKLPTLPYGTMELLN 661
Y + N C +GH E N C+ D +SG CE I +C L + +G++ +
Sbjct: 139 YTAACTNTSC-SGHGECVETINNYTCKCDPGFSGLK--CEQIVNCTALESPEHGSLVCSH 195
Query: 662 --GTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSV 719
G S SC Y C +WS P C + C V
Sbjct: 196 PLGNFSYNSSCSISCDRGYLPSSMETMQCMSSGEWSAPIPACNVVECDAVTNPANGFVEC 255
Query: 720 TGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPT 779
N S T D CE+G++++G C +G W PT
Sbjct: 256 FQNPGSFPWNTTCTFD-----------------CEEGFELMGAQSLQCTSSGNWDNEKPT 298
Query: 780 CQYVDCGNPGRIENGKVTL---PSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLE 836
C+ V C + +NG V P+ + ++ + C+E + L+G + C G W+ +
Sbjct: 299 CKAVTCRAVRQPQNGSVRCSHSPAGEFTFKSSCNFTCEEGFMLQGPAQVECTTQGQWTQQ 358
Query: 837 PPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWN 896
P+C+ + C S+ G + + G + C G+ L G RTC + G W+
Sbjct: 359 IPVCEVVKC---SSLAVPGKINMSCSGEPVFGTVCKFACPEGWTLNGSAARTCGATGHWS 415
Query: 897 GTVPVC 902
G +P C
Sbjct: 416 GLLPTC 421
Score = 82.2 bits (194), Expect = 9e-15
Identities = 50/204 (24%), Positives = 80/204 (39%), Gaps = 6/204 (2%)
Query: 766 TCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTL--PSNATFYGATAFYQCDENWELEGVI 823
TC+ + +SG Q V+C E+G + P Y ++ CD + +
Sbjct: 162 TCKCDPGFSGLKCE-QIVNCTALESPEHGSLVCSHPLGNFSYNSSCSISCDRGYLPSSME 220
Query: 824 RRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKG 883
C +G WS P C + C + + + CE G+ L G
Sbjct: 221 TMQCMSSGEWSAPIPACNVVECDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMG 280
Query: 884 HQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISN---GSTLFGSSVEYYCLSQYQ 940
Q+ C S G W+ P C + CR+ +NG + S+ G F SS + C +
Sbjct: 281 AQSLQCTSSGNWDNEKPTCKAVTCRAVRQPQNGSVRCSHSPAGEFTFKSSCNFTCEEGFM 340
Query: 941 RVGPFLRKCLDDGRWSGEEPSCEL 964
GP +C G+W+ + P CE+
Sbjct: 341 LQGPAQVECTTQGQWTQQIPVCEV 364
Score = 46.4 bits (105), Expect = 6e-04
Identities = 26/73 (35%), Positives = 35/73 (47%), Gaps = 3/73 (4%)
Query: 2 CGHPAVPPNARVS-IPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCG- 59
C P N V N + T ++C+EG+EL GA+ +CT G+W E P C
Sbjct: 242 CDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGNWDNEKPTCKA 301
Query: 60 -TNVAFRKPANQS 71
T A R+P N S
Sbjct: 302 VTCRAVRQPQNGS 314
Score = 38.3 bits (85), Expect = 0.15
Identities = 14/30 (46%), Positives = 19/30 (63%)
Query: 29 YECDEGYELFGARQRECTLRGDWTLEPPFC 58
+ C+EG+ L G Q ECT +G WT + P C
Sbjct: 333 FTCEEGFMLQGPAQVECTTQGQWTQQIPVC 362
Score = 38.3 bits (85), Expect = 0.15
Identities = 20/58 (34%), Positives = 27/58 (46%), Gaps = 2/58 (3%)
Query: 1 RCGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
+C AVP +S E V GT+ + C EG+ L G+ R C G W+ P C
Sbjct: 366 KCSSLAVPGKINMSCSGEP--VFGTVCKFACPEGWTLNGSAARTCGATGHWSGLLPTC 421
Score = 33.9 bits (74), Expect = 3.2
Identities = 18/68 (26%), Positives = 32/68 (47%), Gaps = 2/68 (2%)
Query: 905 IDCRSPGNIENGKIVISN--GSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
++C + + E+G +V S+ G+ + SS C Y +C+ G WS P+C
Sbjct: 178 VNCTALESPEHGSLVCSHPLGNFSYNSSCSISCDRGYLPSSMETMQCMSSGEWSAPIPAC 237
Query: 963 ELATNEAV 970
+ +AV
Sbjct: 238 NVVECDAV 245
>M64554-1|AAA51821.1| 661|Homo sapiens coagulation factor XIIIb
protein.
Length = 661
Score = 124 bits (299), Expect = 2e-27
Identities = 149/543 (27%), Positives = 217/543 (39%), Gaps = 67/543 (12%)
Query: 450 ERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNG--HKAGSLASYTCENGHILSGST 507
+ TC EG W E PRC F C P +SN ++ +K Y C +G+ +G
Sbjct: 73 QTTCTTEG-WSPE-PRC-FKKCTKPD-LSNGYISDVKLLYKIQENMHYGCASGYKTTGGK 128
Query: 508 S--VTCTLGGAWSGVPPSCK-YVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNG 564
V L WS P K + C P ++ G++ T Q+ C Y+ G
Sbjct: 129 DEEVVQCLSDGWSSQPTCRKEHETCLAPELYNGNYSTTQKTFKVKDKVQYECATGYYTAG 188
Query: 565 A---EELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFD--YYVHSTINFHCEAGHK 619
EE+ C G WS P C C + GY Y + F C +
Sbjct: 189 GKKTEEVECLTYG-WSLT-PKCTKLKCSSLRLIENGYFHPVKQTYEEGDVVQFFCHENYY 246
Query: 620 LIGEPNLVCQQDGEWSGDSPTCE--YIDCGKLPTLPYGTMELLNGTTHL-GSVIQYSCTT 676
L G + C G W +SP CE C P LP + + TT+ G ++ C
Sbjct: 247 LSGSDLIQCYNFG-WYPESPVCEGRRNRCPP-PPLPINSKIQTHSTTYRHGEIVHIECEL 304
Query: 677 NYRLVGPVRRTCTEEFQWSDSSPRC----EEIRCSDPIVAEKSIVSVTGNDRSHGHTLIR 732
N+ + G C E S P+C E++ C +P E N ++ H+ I
Sbjct: 305 NFEIHGSAEIRC--EDGKSTEPPKCIEGQEKVACEEPPFIE--------NGAANLHSKI- 353
Query: 733 TSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTC--QYVDCGNPGR 790
Y G V Y C+ GY + G + TC + G+W+ P C +C +P
Sbjct: 354 ----------YYNGDKVTYACKSGYLLHGSNEITC-NRGKWT-LPPECVENNENCKHPPV 401
Query: 791 IENGKVT---LPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPD 847
+ NG V L S AT G++ Y+C+E + L G C E G WS PP+C E +
Sbjct: 402 VMNGAVADGILASYAT--GSSVEYRCNEYYLLRGSKISRC-EQGKWS-SPPVCLEPCTVN 457
Query: 848 PSAQIKAGSGLLVVTSTLSIGGEA-HYQCERGYNLKGHQTRTCISKGQWNGTV--PVCIP 904
+ + + G+ + C++GY+L + +S G V P+C
Sbjct: 458 VDYMNRNNIEMKWKYEGKVLHGDLIDFVCKQGYDLSPLTPLSELSVQCNRGEVKYPLCTR 517
Query: 905 ID----CRSPGNIENGKIVISNGSTLF-GSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEE 959
+ C SP I++G I+ S T GSSVEY C + G CL DG W+
Sbjct: 518 KESKGMCTSPPLIKHGVIISSTVDTYENGSSVEYRCFDHHFLEGSREAYCL-DGMWT-TP 575
Query: 960 PSC 962
P C
Sbjct: 576 PLC 578
Score = 121 bits (292), Expect = 1e-26
Identities = 117/415 (28%), Positives = 177/415 (42%), Gaps = 54/415 (13%)
Query: 566 EELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFD--YYVHSTINFHCEAGHKLIG- 622
E+ C +G WS + P C C +P++ S GY+ Y + +++ C +G+K G
Sbjct: 72 EQTTCTTEG-WSPE-PRC-FKKCTKPDL-SNGYISDVKLLYKIQENMHYGCASGYKTTGG 127
Query: 623 --EPNLVCQQDGEWSGDSPTC--EYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNY 678
E + C DG WS PTC E+ C P L G T + +QY C T Y
Sbjct: 128 KDEEVVQCLSDG-WSSQ-PTCRKEHETC-LAPELYNGNYSTTQKTFKVKDKVQYECATGY 184
Query: 679 RLVGPVRRTCTE--EFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDN 736
G + E + WS +P+C +++CS + E N H
Sbjct: 185 YTAGGKKTEEVECLTYGWS-LTPKCTKLKCSSLRLIE--------NGYFH---------- 225
Query: 737 RDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQ--YVDCGNPGRIENG 794
V TY G +V++ C + Y + G L C + G W +P C+ C P N
Sbjct: 226 -PVKQTYEEGDVVQFFCHENYYLSGSDLIQCYNFG-WYPESPVCEGRRNRCPPPPLPINS 283
Query: 795 KVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKE----ITCPDPSA 850
K+ S +G +C+ N+E+ G C++ S EPP C E + C +P
Sbjct: 284 KIQTHSTTYRHGEIVHIECELNFEIHGSAEIRCEDGK--STEPPKCIEGQEKVACEEPPF 341
Query: 851 QIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPID--CR 908
I+ G+ L + G + Y C+ GY L G TC ++G+W P C+ + C+
Sbjct: 342 -IENGAANLH-SKIYYNGDKVTYACKSGYLLHGSNEITC-NRGKWT-LPPECVENNENCK 397
Query: 909 SPGNIENGKIVISN-GSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
P + NG + S GSSVEY C Y G + +C + G+WS P C
Sbjct: 398 HPPVVMNGAVADGILASYATGSSVEYRCNEYYLLRGSKISRC-EQGKWS-SPPVC 450
Score = 114 bits (275), Expect = 1e-24
Identities = 124/531 (23%), Positives = 208/531 (39%), Gaps = 62/531 (11%)
Query: 437 YSCRENFTLVGNPERT---CGDEGIWDGEAPRCL--FDWCPDPPAVS-NASVTVNGHKAG 490
Y C + G + C +G W + P C + C P + N S T K
Sbjct: 116 YGCASGYKTTGGKDEEVVQCLSDG-WSSQ-PTCRKEHETCLAPELYNGNYSTTQKTFKVK 173
Query: 491 SLASYTCENGHILSG---STSVTCTLGGAWSGVPPSCKYVNCGT-PTIHKGSFVLINGTT 546
Y C G+ +G + V C G WS + P C + C + I G F + T
Sbjct: 174 DKVQYECATGYYTAGGKKTEEVECLTYG-WS-LTPKCTKLKCSSLRLIENGYFHPVKQTY 231
Query: 547 TYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCE--LTSCPEPEVPSGGYMEAFD- 603
G + QF C +Y+L+G++ + C G W + P CE CP P +P ++
Sbjct: 232 EEGDVVQFFCHENYYLSGSDLIQCYNFG-WYPESPVCEGRRNRCPPPPLPINSKIQTHST 290
Query: 604 YYVHSTI-NFHCEAGHKLIGEPNLVCQQDGEWSGDSPTC----EYIDCGKLPTLPYGTME 658
Y H I + CE ++ G + C +DG+ S + P C E + C + P + G
Sbjct: 291 TYRHGEIVHIECELNFEIHGSAEIRC-EDGK-STEPPKCIEGQEKVACEEPPFIENGAAN 348
Query: 659 LLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVS 718
L + + G + Y+C + Y L G TC +W+ P C E
Sbjct: 349 LHSKIYYNGDKVTYACKSGYLLHGSNEITCNRG-KWT-LPPECVE--------------- 391
Query: 719 VTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTP 778
+ H ++ + + +Y G+ V+YRC + Y + G +S CE G+WS + P
Sbjct: 392 -NNENCKHPPVVMNGAVADGILASYATGSSVEYRCNEYYLLRGSKISRCE-QGKWS-SPP 448
Query: 779 TCQYVDCGNPGRIENGKVTLP---SNATFYGATAFYQCDENWELEGV--IRRMCQENGTW 833
C N + + + +G + C + ++L + + + +
Sbjct: 449 VCLEPCTVNVDYMNRNNIEMKWKYEGKVLHGDLIDFVCKQGYDLSPLTPLSELSVQCNRG 508
Query: 834 SLEPPIC--KEI--TCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTC 889
++ P+C KE C P IK G + T G Y+C + L+G + C
Sbjct: 509 EVKYPLCTRKESKGMCTSPPL-IKHGVIISSTVDTYENGSSVEYRCFDHHFLEGSREAYC 567
Query: 890 ISKGQWNGTVPVCIPIDCRSPGNIENGKIVI-----SNGSTLFGSSVEYYC 935
+ G W T P+C+ S +E +++ + L G +E+ C
Sbjct: 568 LD-GMWT-TPPLCLEPCTLSFTEMEKNNLLLKWDFDNRPHILHGEYIEFIC 616
Score = 110 bits (264), Expect = 3e-23
Identities = 117/456 (25%), Positives = 181/456 (39%), Gaps = 44/456 (9%)
Query: 346 CQYLPPTCGSPDKLL-NTTILGNDYDVGSRIVYKCPEGHMLLGDKSRH---CKKDGFWSG 401
C+ TC +P+ N + + V ++ Y+C G+ G K C G WS
Sbjct: 146 CRKEHETCLAPELYNGNYSTTQKTFKVKDKVQYECATGYYTAGGKKTEEVECLTYG-WS- 203
Query: 402 APPSCKYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDG 461
P C + C L IE+G + G + C EN+ L G+ C + G W
Sbjct: 204 LTPKCTKLKCSSLRLIENGYFHPVKQTYEEGDVVQFFCHENYYLSGSDLIQCYNFG-WYP 262
Query: 462 EAPRC--LFDWCPDPPAVSNASVTVNG--HKAGSLASYTCENGHILSGSTSVTCTLGGAW 517
E+P C + CP PP N+ + + ++ G + CE + GS + C G
Sbjct: 263 ESPVCEGRRNRCPPPPLPINSKIQTHSTTYRHGEIVHIECELNFEIHGSAEIRCEDGK-- 320
Query: 518 SGVPPSC----KYVNCGTPT-IHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNR 572
S PP C + V C P I G+ L + G + C+ Y L+G+ E+ CNR
Sbjct: 321 STEPPKCIEGQEKVACEEPPFIENGAANLHSKIYYNGDKVTYACKSGYLLHGSNEITCNR 380
Query: 573 DGKWSYDIPSC--ELTSCPEPEVPSGGYME---AFDYYVHSTINFHCEAGHKLIGEPNLV 627
GKW+ P C +C P V G + Y S++ + C + L G
Sbjct: 381 -GKWTLP-PECVENNENCKHPPVVMNGAVADGILASYATGSSVEYRCNEYYLLRGSKISR 438
Query: 628 CQQDGEWSGDSPTCEYIDCGKLPTLPYGTMEL---LNGTTHLGSVIQYSCTTNYRLVGPV 684
C+Q G+WS P C + + +E+ G G +I + C Y L P+
Sbjct: 439 CEQ-GKWS-SPPVCLEPCTVNVDYMNRNNIEMKWKYEGKVLHGDLIDFVCKQGYDL-SPL 495
Query: 685 RRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYR 744
S+ S +C P+ K + + H +I +S +TY
Sbjct: 496 T-------PLSELSVQCNRGEVKYPLCTRKESKGMCTSPPLIKHGVIISS----TVDTYE 544
Query: 745 IGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTC 780
G+ V+YRC + + G + C D G W+ T P C
Sbjct: 545 NGSSVEYRCFDHHFLEGSREAYCLD-GMWT-TPPLC 578
Score = 35.9 bits (79), Expect = 0.79
Identities = 22/59 (37%), Positives = 26/59 (44%), Gaps = 5/59 (8%)
Query: 24 GTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTNVAFRKPANQSTTVRGGAAANG 82
G Y C GY L G+ + C RG WTL PP C N + V GA A+G
Sbjct: 357 GDKVTYACKSGYLLHGSNEITCN-RGKWTL-PPECVEN---NENCKHPPVVMNGAVADG 410
Score = 35.1 bits (77), Expect = 1.4
Identities = 19/57 (33%), Positives = 27/57 (47%), Gaps = 2/57 (3%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C HP V N V+ + G+ Y C+E Y L G++ C +G W+ PP C
Sbjct: 396 CKHPPVVMNGAVADGILASYATGSSVEYRCNEYYLLRGSKISRCE-QGKWS-SPPVC 450
>X07523-1|CAA30403.1| 449|Homo sapiens complement factor H protein.
Length = 449
Score = 117 bits (281), Expect = 3e-25
Identities = 103/375 (27%), Positives = 151/375 (40%), Gaps = 31/375 (8%)
Query: 346 CQYLPPTCGSP-DKLLNTTIL--GNDYDVGSRIVYKCPEGHMLLGD-KSRHCKKDGFWSG 401
CQ P CG P D T L GN ++ G + VY C EG+ LLG+ R C DG W+
Sbjct: 80 CQKRP--CGHPGDTPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYRECDTDG-WTN 136
Query: 402 APPSCKYVNCGGLTPIEDGDV---ALIDNRTTHGARAL-YSCRENFTLVGNPERTCGDEG 457
P C+ V C +T E+G + A+ +R H +A+ + C + + G+ E C D+G
Sbjct: 137 DIPICEVVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCSDDG 196
Query: 458 IWDGEAPRCLFDWCPDPPAVSNASVTVN-GHKAGSLASYTCENGHILSGSTSVTCTLGGA 516
W E P+C+ C P ++ + ++ +K Y C G+ S CT G
Sbjct: 197 FWSKEKPKCVEISCKSPDVINGSPISQKIIYKENERFQYKCNMGYEYSERGDAVCTESG- 255
Query: 517 WSGVPPSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYW-LNGAEELVCNRDGK 575
W + PSC+ +C P I G + + G + C ++ C G
Sbjct: 256 WRPL-PSCEEKSCDNPYIPNGDYSPLRIKHRTGDEITYQCRNGFYPATRGNTAKCTSTG- 313
Query: 576 WSYDIPSCELTSCPEPEVPSGG-YME-----AFDYYVHSTINFHCEAGHKLIGE---PNL 626
W P C L C P++ GG Y E F V +++C+ + ++
Sbjct: 314 W-IPAPRCTLKPCDYPDIKHGGLYHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDHI 372
Query: 627 VCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRR 686
C QDG WS P C P L G + G I +C Y L
Sbjct: 373 HCTQDG-WSPAVPCLR--KC-YFPYLENGYNQNYGRKFVQGKSIDVACHPGYALPKAQTT 428
Query: 687 TCTEEFQWSDSSPRC 701
E WS +PRC
Sbjct: 429 VTCMENGWS-PTPRC 442
Score = 109 bits (261), Expect = 7e-23
Identities = 111/450 (24%), Positives = 171/450 (38%), Gaps = 43/450 (9%)
Query: 346 CQYLPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPP- 404
C LPP + ++L + Y G++ +YKC G+ LG+ C+K G W P
Sbjct: 21 CNELPPRRNT--EILTGSWSDQTYPEGTQAIYKCRPGYRSLGNVIMVCRK-GEWVALNPL 77
Query: 405 -SCKYVNCG--GLTPIEDGDVALI-DNRTTHGARALYSCRENFTLVGNPE-RTCGDEGIW 459
C+ CG G TP G L N +G +A+Y+C E + L+G R C +G W
Sbjct: 78 RKCQKRPCGHPGDTPF--GTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYRECDTDG-W 134
Query: 460 DGEAPRCLFDWCPDPPAVSNASVTVNG------HKAGSLASYTCENGHILSGSTSVTCTL 513
+ P C C A N + + + G + C +G+ + G + C+
Sbjct: 135 TNDIPICEVVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCSD 194
Query: 514 GGAWSGVPPSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRD 573
G WS P C ++C +P + GS + Q+ C Y + + VC
Sbjct: 195 DGFWSKEKPKCVEISCKSPDVINGSPISQKIIYKENERFQYKCNMGYEYSERGDAVCTES 254
Query: 574 GKWSYDIPSCELTSCPEPEVPSGGYME-AFDYYVHSTINFHCEAGHKLIGEPNLV-CQQD 631
G W +PSCE SC P +P+G Y + I + C G N C
Sbjct: 255 G-WR-PLPSCEEKSCDNPYIPNGDYSPLRIKHRTGDEITYQCRNGFYPATRGNTAKCTST 312
Query: 632 GEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEE 691
G W +P C C P + +G + N V + Y C E
Sbjct: 313 G-WI-PAPRCTLKPC-DYPDIKHGGLYHENMRRPYFPVAVGKYYSYY---------CDEH 360
Query: 692 FQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKY 751
F+ + S + I C+ + R + N++ G + G +
Sbjct: 361 FE-TPSGSYWDHIHCT-----QDGWSPAVPCLRKCYFPYLENGYNQNYGRKFVQGKSIDV 414
Query: 752 RCEKGYKV-IGESLSTCEDNGQWSGTTPTC 780
C GY + ++ TC +NG WS TP C
Sbjct: 415 ACHPGYALPKAQTTVTCMENG-WS-PTPRC 442
Score = 107 bits (256), Expect = 3e-22
Identities = 100/366 (27%), Positives = 148/366 (40%), Gaps = 48/366 (13%)
Query: 612 FHCEAGHKLIGEPNLVCQQDGEWSGDSPT--CEYIDCGKLPTLPYGTMELLNGTT-HLGS 668
+ C G++ +G +VC++ GEW +P C+ CG P+GT L G G
Sbjct: 50 YKCRPGYRSLGNVIMVCRK-GEWVALNPLRKCQKRPCGHPGDTPFGTFTLTGGNVFEYGV 108
Query: 669 VIQYSCTTNYRLVGPVR-RTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHG 727
Y+C Y+L+G + R C + W++ P CE ++C P+ A ++ V
Sbjct: 109 KAVYTCNEGYQLLGEINYRECDTD-GWTNDIPICEVVKCL-PVTAPENGKIV-------- 158
Query: 728 HTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGN 787
S + Y G V++ C GYK+ G+ C D+G WS P C + C +
Sbjct: 159 ------SSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCSDDGFWSKEKPKCVEISCKS 212
Query: 788 PGRIENG----KVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEI 843
P I K+ N F Y+C+ +E +C E+G L P C+E
Sbjct: 213 PDVINGSPISQKIIYKENERFQ-----YKCNMGYEYSERGDAVCTESGWRPL--PSCEEK 265
Query: 844 TCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERG-YNLKGHQTRTCISKGQWNGTVPVC 902
+C +P S L + T G E YQC G Y T C S G W P C
Sbjct: 266 SCDNPYIPNGDYSPLRIKHRT---GDEITYQCRNGFYPATRGNTAKCTSTG-WI-PAPRC 320
Query: 903 IPIDCRSPGNIENGKIVISNGSTLF-----GSSVEYYCLSQYQR-VGPFLR--KCLDDGR 954
C P +I++G + N + G YYC ++ G + C DG
Sbjct: 321 TLKPCDYP-DIKHGGLYHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDHIHCTQDG- 378
Query: 955 WSGEEP 960
WS P
Sbjct: 379 WSPAVP 384
Score = 104 bits (249), Expect = 2e-21
Identities = 68/228 (29%), Positives = 97/228 (42%), Gaps = 11/228 (4%)
Query: 742 TYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTP--TCQYVDCGNPGRIENGKVTLP 799
TY G Y+C GY+ +G + C G+W P CQ CG+PG G TL
Sbjct: 41 TYPEGTQAIYKCRPGYRSLGNVIMVCR-KGEWVALNPLRKCQKRPCGHPGDTPFGTFTLT 99
Query: 800 SNATF-YGATAFYQCDENWELEGVIR-RMCQENGTWSLEPPICKEITCPDPSA--QIKAG 855
F YG A Y C+E ++L G I R C +G W+ + PIC+ + C +A K
Sbjct: 100 GGNVFEYGVKAVYTCNEGYQLLGEINYRECDTDG-WTNDIPICEVVKCLPVTAPENGKIV 158
Query: 856 SGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIEN 915
S + G + C GY ++G + C G W+ P C+ I C+SP ++ N
Sbjct: 159 SSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCSDDGFWSKEKPKCVEISCKSP-DVIN 217
Query: 916 GKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
G + +Y C Y+ C + G W PSCE
Sbjct: 218 GSPISQKIIYKENERFQYKCNMGYEYSERGDAVCTESG-WR-PLPSCE 263
Score = 101 bits (241), Expect = 2e-20
Identities = 84/320 (26%), Positives = 123/320 (38%), Gaps = 23/320 (7%)
Query: 406 CKYVNCGGLTPIEDGDV---ALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGE 462
C +C L P + ++ + D G +A+Y CR + +GN C +G W
Sbjct: 16 CVAEDCNELPPRRNTEILTGSWSDQTYPEGTQAIYKCRPGYRSLGNVIMVCR-KGEWVAL 74
Query: 463 AP--RCLFDWCPDPPAVSNASVTVNGHKA---GSLASYTCENGHILSGSTSVT-CTLGGA 516
P +C C P + T+ G G A YTC G+ L G + C G
Sbjct: 75 NPLRKCQKRPCGHPGDTPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYRECDTDG- 133
Query: 517 WSGVPPSCKYVNCGTPTIHKGSFVLINGTTT-----YGSIAQFTCEPDYWLNGAEELVCN 571
W+ P C+ V C T + ++ + +G +F C Y + G EE+ C+
Sbjct: 134 WTNDIPICEVVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCS 193
Query: 572 RDGKWSYDIPSCELTSCPEPEVPSGG-YMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQ 630
DG WS + P C SC P+V +G + Y + + C G++ + VC +
Sbjct: 194 DDGFWSKEKPKCVEISCKSPDVINGSPISQKIIYKENERFQYKCNMGYEYSERGDAVCTE 253
Query: 631 DGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTN-YRLVGPVRRTCT 689
G W P+CE C P +P G L G I Y C Y CT
Sbjct: 254 SG-WR-PLPSCEEKSCDN-PYIPNGDYSPLRIKHRTGDEITYQCRNGFYPATRGNTAKCT 310
Query: 690 EEFQWSDSSPRCEEIRCSDP 709
W +PRC C P
Sbjct: 311 ST-GWI-PAPRCTLKPCDYP 328
Score = 94.3 bits (224), Expect = 2e-18
Identities = 86/337 (25%), Positives = 126/337 (37%), Gaps = 43/337 (12%)
Query: 641 CEYIDCGKLPTLPYGTMELLNG-----TTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWS 695
C DC +LP P E+L G T G+ Y C YR +G V C + +W
Sbjct: 16 CVAEDCNELP--PRRNTEILTGSWSDQTYPEGTQAIYKCRPGYRSLGNVIMVCRKG-EWV 72
Query: 696 DSSP--RCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRC 753
+P +C++ C P ++TG GN + G Y C
Sbjct: 73 ALNPLRKCQKRPCGHPGDTPFGTFTLTG------------------GNVFEYGVKAVYTC 114
Query: 754 EKGYKVIGE-SLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTL----PSNATFYGAT 808
+GY+++GE + C+ +G W+ P C+ V C ENGK+ P +G
Sbjct: 115 NEGYQLLGEINYRECDTDG-WTNDIPICEVVKCLPVTAPENGKIVSSAMEPDREYHFGQA 173
Query: 809 AFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIG 868
+ C+ +++EG C ++G WS E P C EI+C P + ++
Sbjct: 174 VRFVCNSGYKIEGDEEMHCSDDGFWSKEKPKCVEISCKSPDVINGSPISQKIIYKE---N 230
Query: 869 GEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFG 928
Y+C GY C G W +P C C +P I NG G
Sbjct: 231 ERFQYKCNMGYEYSERGDAVCTESG-WR-PLPSCEEKSCDNP-YIPNGDYSPLRIKHRTG 287
Query: 929 SSVEYYCLSQ-YQRVGPFLRKCLDDGRWSGEEPSCEL 964
+ Y C + Y KC G W P C L
Sbjct: 288 DEITYQCRNGFYPATRGNTAKCTSTG-WI-PAPRCTL 322
Score = 79.8 bits (188), Expect = 5e-14
Identities = 78/312 (25%), Positives = 126/312 (40%), Gaps = 27/312 (8%)
Query: 345 ICQYLPPTCGSPDKLLNTTILGN-DYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAP 403
+ + LP T K++++ + + +Y G + + C G+ + GD+ HC DGFWS
Sbjct: 143 VVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCSDDGFWSKEK 202
Query: 404 PSCKYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEA 463
P C ++C I ++ R Y C + + C + G W
Sbjct: 203 PKCVEISCKSPDVINGSPISQ-KIIYKENERFQYKCNMGYEYSERGDAVCTESG-W-RPL 259
Query: 464 PRCLFDWCPDPPAVSNA--SVTVNGHKAGSLASYTCENG-HILSGSTSVTCTLGGAWSGV 520
P C C D P + N S H+ G +Y C NG + + + CT G W +
Sbjct: 260 PSCEEKSC-DNPYIPNGDYSPLRIKHRTGDEITYQCRNGFYPATRGNTAKCTSTG-W--I 315
Query: 521 P-PSCKYVNCGTPTIHKGSFVLINGTTTY-----GSIAQFTCEPDYWL-NGA--EELVCN 571
P P C C P I G N Y G + C+ + +G+ + + C
Sbjct: 316 PAPRCTLKPCDYPDIKHGGLYHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDHIHCT 375
Query: 572 RDGKWSYDIPSCELTSCPEPEVPSGGYMEAFDYYVH-STINFHCEAGHKL-IGEPNLVCQ 629
+DG WS +P C L C P + +G +V +I+ C G+ L + + C
Sbjct: 376 QDG-WSPAVP-C-LRKCYFPYLENGYNQNYGRKFVQGKSIDVACHPGYALPKAQTTVTCM 432
Query: 630 QDGEWSGDSPTC 641
++G WS +P C
Sbjct: 433 ENG-WS-PTPRC 442
Score = 45.6 bits (103), Expect = 0.001
Identities = 23/58 (39%), Positives = 28/58 (48%), Gaps = 2/58 (3%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFG-ARQRECTLRGDWTLEPPFC 58
CGHP P ++ G AVY C+EGY+L G REC G WT + P C
Sbjct: 85 CGHPGDTPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYRECDTDG-WTNDIPIC 141
>X04697-1|CAB41739.1| 397|Homo sapiens protein ( Human mRNA for
complement factor H 38-kDa N-terminal fragment. ).
Length = 397
Score = 117 bits (281), Expect = 3e-25
Identities = 103/375 (27%), Positives = 151/375 (40%), Gaps = 31/375 (8%)
Query: 346 CQYLPPTCGSP-DKLLNTTIL--GNDYDVGSRIVYKCPEGHMLLGD-KSRHCKKDGFWSG 401
CQ P CG P D T L GN ++ G + VY C EG+ LLG+ R C DG W+
Sbjct: 28 CQKRP--CGHPGDTPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYRECDTDG-WTN 84
Query: 402 APPSCKYVNCGGLTPIEDGDV---ALIDNRTTHGARAL-YSCRENFTLVGNPERTCGDEG 457
P C+ V C +T E+G + A+ +R H +A+ + C + + G+ E C D+G
Sbjct: 85 DIPICEVVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCSDDG 144
Query: 458 IWDGEAPRCLFDWCPDPPAVSNASVTVN-GHKAGSLASYTCENGHILSGSTSVTCTLGGA 516
W E P+C+ C P ++ + ++ +K Y C G+ S CT G
Sbjct: 145 FWSKEKPKCVEISCKSPDVINGSPISQKIIYKENERFQYKCNMGYEYSERGDAVCTESG- 203
Query: 517 WSGVPPSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYW-LNGAEELVCNRDGK 575
W + PSC+ +C P I G + + G + C ++ C G
Sbjct: 204 WRPL-PSCEEKSCDNPYIPNGDYSPLRIKHRTGDEITYQCRNGFYPATRGNTAKCTSTG- 261
Query: 576 WSYDIPSCELTSCPEPEVPSGG-YME-----AFDYYVHSTINFHCEAGHKLIGE---PNL 626
W P C L C P++ GG Y E F V +++C+ + ++
Sbjct: 262 W-IPAPRCTLKPCDYPDIKHGGLYHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDHI 320
Query: 627 VCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRR 686
C QDG WS P C P L G + G I +C Y L
Sbjct: 321 HCTQDG-WSPAVPCLR--KC-YFPYLENGYNQNYGRKFVQGKSIDVACHPGYALPKAQTT 376
Query: 687 TCTEEFQWSDSSPRC 701
E WS +PRC
Sbjct: 377 VTCMENGWS-PTPRC 390
Score = 103 bits (246), Expect = 5e-21
Identities = 99/361 (27%), Positives = 146/361 (40%), Gaps = 48/361 (13%)
Query: 617 GHKLIGEPNLVCQQDGEWSGDSPT--CEYIDCGKLPTLPYGTMELLNGTT-HLGSVIQYS 673
G++ +G +VC++ GEW +P C+ CG P+GT L G G Y+
Sbjct: 3 GYRSLGNVIMVCRK-GEWVALNPLRKCQKRPCGHPGDTPFGTFTLTGGNVFEYGVKAVYT 61
Query: 674 CTTNYRLVGPVR-RTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIR 732
C Y+L+G + R C + W++ P CE ++C P+ A ++ V
Sbjct: 62 CNEGYQLLGEINYRECDTD-GWTNDIPICEVVKCL-PVTAPENGKIV------------- 106
Query: 733 TSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIE 792
S + Y G V++ C GYK+ G+ C D+G WS P C + C +P I
Sbjct: 107 -SSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCSDDGFWSKEKPKCVEISCKSPDVIN 165
Query: 793 NG----KVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDP 848
K+ N F Y+C+ +E +C E+G L P C+E +C +P
Sbjct: 166 GSPISQKIIYKENERFQ-----YKCNMGYEYSERGDAVCTESGWRPL--PSCEEKSCDNP 218
Query: 849 SAQIKAGSGLLVVTSTLSIGGEAHYQCERG-YNLKGHQTRTCISKGQWNGTVPVCIPIDC 907
S L + T G E YQC G Y T C S G W P C C
Sbjct: 219 YIPNGDYSPLRIKHRT---GDEITYQCRNGFYPATRGNTAKCTSTG-WI-PAPRCTLKPC 273
Query: 908 RSPGNIENGKIVISNGSTLF-----GSSVEYYCLSQYQR-VGPFLR--KCLDDGRWSGEE 959
P +I++G + N + G YYC ++ G + C DG WS
Sbjct: 274 DYP-DIKHGGLYHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDHIHCTQDG-WSPAV 331
Query: 960 P 960
P
Sbjct: 332 P 332
Score = 94.3 bits (224), Expect = 2e-18
Identities = 63/214 (29%), Positives = 91/214 (42%), Gaps = 11/214 (5%)
Query: 756 GYKVIGESLSTCEDNGQWSGTTPT--CQYVDCGNPGRIENGKVTLPSNATF-YGATAFYQ 812
GY+ +G + C G+W P CQ CG+PG G TL F YG A Y
Sbjct: 3 GYRSLGNVIMVCR-KGEWVALNPLRKCQKRPCGHPGDTPFGTFTLTGGNVFEYGVKAVYT 61
Query: 813 CDENWELEGVIR-RMCQENGTWSLEPPICKEITCPDPSA--QIKAGSGLLVVTSTLSIGG 869
C+E ++L G I R C +G W+ + PIC+ + C +A K S + G
Sbjct: 62 CNEGYQLLGEINYRECDTDG-WTNDIPICEVVKCLPVTAPENGKIVSSAMEPDREYHFGQ 120
Query: 870 EAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGS 929
+ C GY ++G + C G W+ P C+ I C+SP ++ NG +
Sbjct: 121 AVRFVCNSGYKIEGDEEMHCSDDGFWSKEKPKCVEISCKSP-DVINGSPISQKIIYKENE 179
Query: 930 SVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
+Y C Y+ C + G W PSCE
Sbjct: 180 RFQYKCNMGYEYSERGDAVCTESG-WR-PLPSCE 211
Score = 85.8 bits (203), Expect = 7e-16
Identities = 61/231 (26%), Positives = 89/231 (38%), Gaps = 15/231 (6%)
Query: 740 GNTYRIGALVKYRCEKGYKVIGE-SLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTL 798
GN + G Y C +GY+++GE + C+ +G W+ P C+ V C ENGK+
Sbjct: 49 GNVFEYGVKAVYTCNEGYQLLGEINYRECDTDG-WTNDIPICEVVKCLPVTAPENGKIVS 107
Query: 799 ----PSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKA 854
P +G + C+ +++EG C ++G WS E P C EI+C P +
Sbjct: 108 SAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCSDDGFWSKEKPKCVEISCKSPDVINGS 167
Query: 855 GSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIE 914
++ Y+C GY C G W +P C C +P I
Sbjct: 168 PISQKIIYKE---NERFQYKCNMGYEYSERGDAVCTESG-WR-PLPSCEEKSCDNP-YIP 221
Query: 915 NGKIVISNGSTLFGSSVEYYCLSQ-YQRVGPFLRKCLDDGRWSGEEPSCEL 964
NG G + Y C + Y KC G W P C L
Sbjct: 222 NGDYSPLRIKHRTGDEITYQCRNGFYPATRGNTAKCTSTG-WI-PAPRCTL 270
Score = 85.4 bits (202), Expect = 1e-15
Identities = 74/277 (26%), Positives = 105/277 (37%), Gaps = 20/277 (7%)
Query: 446 VGNPERTCGDEGIWDGEAP--RCLFDWCPDPPAVSNASVTVNGHKA---GSLASYTCENG 500
+GN C +G W P +C C P + T+ G G A YTC G
Sbjct: 7 LGNVIMVCR-KGEWVALNPLRKCQKRPCGHPGDTPFGTFTLTGGNVFEYGVKAVYTCNEG 65
Query: 501 HILSGSTSVT-CTLGGAWSGVPPSCKYVNCGTPTIHKGSFVLINGTTT-----YGSIAQF 554
+ L G + C G W+ P C+ V C T + ++ + +G +F
Sbjct: 66 YQLLGEINYRECDTDG-WTNDIPICEVVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRF 124
Query: 555 TCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGG-YMEAFDYYVHSTINFH 613
C Y + G EE+ C+ DG WS + P C SC P+V +G + Y + +
Sbjct: 125 VCNSGYKIEGDEEMHCSDDGFWSKEKPKCVEISCKSPDVINGSPISQKIIYKENERFQYK 184
Query: 614 CEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYS 673
C G++ + VC + G W P+CE C P +P G L G I Y
Sbjct: 185 CNMGYEYSERGDAVCTESG-WR-PLPSCEEKSCDN-PYIPNGDYSPLRIKHRTGDEITYQ 241
Query: 674 CTTN-YRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDP 709
C Y CT W +PRC C P
Sbjct: 242 CRNGFYPATRGNTAKCTST-GWI-PAPRCTLKPCDYP 276
Score = 80.6 bits (190), Expect = 3e-14
Identities = 69/260 (26%), Positives = 108/260 (41%), Gaps = 43/260 (16%)
Query: 568 LVCNRDGKWSYDIP--SCELTSCPEP-EVPSGGYM----EAFDYYVHSTINFHCEAGHKL 620
+VC R G+W P C+ C P + P G + F+Y V + + C G++L
Sbjct: 12 MVC-RKGEWVALNPLRKCQKRPCGHPGDTPFGTFTLTGGNVFEYGVKAV--YTCNEGYQL 68
Query: 621 IGEPNL-VCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTT------HLGSVIQYS 673
+GE N C DG W+ D P CE + C LP ++++ H G +++
Sbjct: 69 LGEINYRECDTDG-WTNDIPICEVVKC--LPVTAPENGKIVSSAMEPDREYHFGQAVRFV 125
Query: 674 CTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRT 733
C + Y++ G C+++ WS P+C EI C P V S +S +I
Sbjct: 126 CNSGYKIEGDEEMHCSDDGFWSKEKPKCVEISCKSPDVINGSPIS---------QKII-- 174
Query: 734 SDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIEN 793
Y+ +Y+C GY+ + C ++G W P+C+ C NP I N
Sbjct: 175 ---------YKENERFQYKCNMGYEYSERGDAVCTESG-WR-PLPSCEEKSCDNP-YIPN 222
Query: 794 GKVTLPSNATFYGATAFYQC 813
G + G YQC
Sbjct: 223 GDYSPLRIKHRTGDEITYQC 242
Score = 79.8 bits (188), Expect = 5e-14
Identities = 78/312 (25%), Positives = 126/312 (40%), Gaps = 27/312 (8%)
Query: 345 ICQYLPPTCGSPDKLLNTTILGN-DYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAP 403
+ + LP T K++++ + + +Y G + + C G+ + GD+ HC DGFWS
Sbjct: 91 VVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCSDDGFWSKEK 150
Query: 404 PSCKYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEA 463
P C ++C I ++ R Y C + + C + G W
Sbjct: 151 PKCVEISCKSPDVINGSPISQ-KIIYKENERFQYKCNMGYEYSERGDAVCTESG-W-RPL 207
Query: 464 PRCLFDWCPDPPAVSNA--SVTVNGHKAGSLASYTCENG-HILSGSTSVTCTLGGAWSGV 520
P C C D P + N S H+ G +Y C NG + + + CT G W +
Sbjct: 208 PSCEEKSC-DNPYIPNGDYSPLRIKHRTGDEITYQCRNGFYPATRGNTAKCTSTG-W--I 263
Query: 521 P-PSCKYVNCGTPTIHKGSFVLINGTTTY-----GSIAQFTCEPDYWL-NGA--EELVCN 571
P P C C P I G N Y G + C+ + +G+ + + C
Sbjct: 264 PAPRCTLKPCDYPDIKHGGLYHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDHIHCT 323
Query: 572 RDGKWSYDIPSCELTSCPEPEVPSGGYMEAFDYYVH-STINFHCEAGHKL-IGEPNLVCQ 629
+DG WS +P C L C P + +G +V +I+ C G+ L + + C
Sbjct: 324 QDG-WSPAVP-C-LRKCYFPYLENGYNQNYGRKFVQGKSIDVACHPGYALPKAQTTVTCM 380
Query: 630 QDGEWSGDSPTC 641
++G WS +P C
Sbjct: 381 ENG-WS-PTPRC 390
Score = 45.6 bits (103), Expect = 0.001
Identities = 23/58 (39%), Positives = 28/58 (48%), Gaps = 2/58 (3%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFG-ARQRECTLRGDWTLEPPFC 58
CGHP P ++ G AVY C+EGY+L G REC G WT + P C
Sbjct: 33 CGHPGDTPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYRECDTDG-WTNDIPIC 89
>BC110643-1|AAI10644.1| 449|Homo sapiens complement factor H
protein.
Length = 449
Score = 117 bits (281), Expect = 3e-25
Identities = 103/375 (27%), Positives = 151/375 (40%), Gaps = 31/375 (8%)
Query: 346 CQYLPPTCGSP-DKLLNTTIL--GNDYDVGSRIVYKCPEGHMLLGD-KSRHCKKDGFWSG 401
CQ P CG P D T L GN ++ G + VY C EG+ LLG+ R C DG W+
Sbjct: 80 CQKRP--CGHPGDTPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYRECDTDG-WTN 136
Query: 402 APPSCKYVNCGGLTPIEDGDV---ALIDNRTTHGARAL-YSCRENFTLVGNPERTCGDEG 457
P C+ V C +T E+G + A+ +R H +A+ + C + + G+ E C D+G
Sbjct: 137 DIPICEVVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCSDDG 196
Query: 458 IWDGEAPRCLFDWCPDPPAVSNASVTVN-GHKAGSLASYTCENGHILSGSTSVTCTLGGA 516
W E P+C+ C P ++ + ++ +K Y C G+ S CT G
Sbjct: 197 FWSKEKPKCVEISCKSPDVINGSPISQKIIYKENERFQYKCNMGYEYSERGDAVCTESG- 255
Query: 517 WSGVPPSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYW-LNGAEELVCNRDGK 575
W + PSC+ +C P I G + + G + C ++ C G
Sbjct: 256 WRPL-PSCEEKSCDNPYIPNGDYSPLRIKHRTGDEITYQCRNGFYPATRGNTAKCTSTG- 313
Query: 576 WSYDIPSCELTSCPEPEVPSGG-YME-----AFDYYVHSTINFHCEAGHKLIGE---PNL 626
W P C L C P++ GG Y E F V +++C+ + ++
Sbjct: 314 W-IPAPRCTLKPCDYPDIKHGGLYHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDHI 372
Query: 627 VCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRR 686
C QDG WS P C P L G + G I +C Y L
Sbjct: 373 HCTQDG-WSPAVPCLR--KC-YFPYLENGYNQNYGRKFVQGKSIDVACHPGYALPKAQTT 428
Query: 687 TCTEEFQWSDSSPRC 701
E WS +PRC
Sbjct: 429 VTCMENGWS-PTPRC 442
Score = 109 bits (261), Expect = 7e-23
Identities = 111/450 (24%), Positives = 171/450 (38%), Gaps = 43/450 (9%)
Query: 346 CQYLPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPP- 404
C LPP + ++L + Y G++ +YKC G+ LG+ C+K G W P
Sbjct: 21 CNELPPRRNT--EILTGSWSDQTYPEGTQAIYKCRPGYRSLGNVIMVCRK-GEWVALNPL 77
Query: 405 -SCKYVNCG--GLTPIEDGDVALI-DNRTTHGARALYSCRENFTLVGNPE-RTCGDEGIW 459
C+ CG G TP G L N +G +A+Y+C E + L+G R C +G W
Sbjct: 78 RKCQKRPCGHPGDTPF--GTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYRECDTDG-W 134
Query: 460 DGEAPRCLFDWCPDPPAVSNASVTVNG------HKAGSLASYTCENGHILSGSTSVTCTL 513
+ P C C A N + + + G + C +G+ + G + C+
Sbjct: 135 TNDIPICEVVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCSD 194
Query: 514 GGAWSGVPPSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRD 573
G WS P C ++C +P + GS + Q+ C Y + + VC
Sbjct: 195 DGFWSKEKPKCVEISCKSPDVINGSPISQKIIYKENERFQYKCNMGYEYSERGDAVCTES 254
Query: 574 GKWSYDIPSCELTSCPEPEVPSGGYME-AFDYYVHSTINFHCEAGHKLIGEPNLV-CQQD 631
G W +PSCE SC P +P+G Y + I + C G N C
Sbjct: 255 G-WR-PLPSCEEKSCDNPYIPNGDYSPLRIKHRTGDEITYQCRNGFYPATRGNTAKCTST 312
Query: 632 GEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEE 691
G W +P C C P + +G + N V + Y C E
Sbjct: 313 G-WI-PAPRCTLKPC-DYPDIKHGGLYHENMRRPYFPVAVGKYYSYY---------CDEH 360
Query: 692 FQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKY 751
F+ + S + I C+ + R + N++ G + G +
Sbjct: 361 FE-TPSGSYWDHIHCT-----QDGWSPAVPCLRKCYFPYLENGYNQNYGRKFVQGKSIDV 414
Query: 752 RCEKGYKV-IGESLSTCEDNGQWSGTTPTC 780
C GY + ++ TC +NG WS TP C
Sbjct: 415 ACHPGYALPKAQTTVTCMENG-WS-PTPRC 442
Score = 107 bits (256), Expect = 3e-22
Identities = 100/366 (27%), Positives = 148/366 (40%), Gaps = 48/366 (13%)
Query: 612 FHCEAGHKLIGEPNLVCQQDGEWSGDSPT--CEYIDCGKLPTLPYGTMELLNGTT-HLGS 668
+ C G++ +G +VC++ GEW +P C+ CG P+GT L G G
Sbjct: 50 YKCRPGYRSLGNVIMVCRK-GEWVALNPLRKCQKRPCGHPGDTPFGTFTLTGGNVFEYGV 108
Query: 669 VIQYSCTTNYRLVGPVR-RTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHG 727
Y+C Y+L+G + R C + W++ P CE ++C P+ A ++ V
Sbjct: 109 KAVYTCNEGYQLLGEINYRECDTD-GWTNDIPICEVVKCL-PVTAPENGKIV-------- 158
Query: 728 HTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGN 787
S + Y G V++ C GYK+ G+ C D+G WS P C + C +
Sbjct: 159 ------SSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCSDDGFWSKEKPKCVEISCKS 212
Query: 788 PGRIENG----KVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEI 843
P I K+ N F Y+C+ +E +C E+G L P C+E
Sbjct: 213 PDVINGSPISQKIIYKENERFQ-----YKCNMGYEYSERGDAVCTESGWRPL--PSCEEK 265
Query: 844 TCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERG-YNLKGHQTRTCISKGQWNGTVPVC 902
+C +P S L + T G E YQC G Y T C S G W P C
Sbjct: 266 SCDNPYIPNGDYSPLRIKHRT---GDEITYQCRNGFYPATRGNTAKCTSTG-WI-PAPRC 320
Query: 903 IPIDCRSPGNIENGKIVISNGSTLF-----GSSVEYYCLSQYQR-VGPFLR--KCLDDGR 954
C P +I++G + N + G YYC ++ G + C DG
Sbjct: 321 TLKPCDYP-DIKHGGLYHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDHIHCTQDG- 378
Query: 955 WSGEEP 960
WS P
Sbjct: 379 WSPAVP 384
Score = 104 bits (249), Expect = 2e-21
Identities = 68/228 (29%), Positives = 97/228 (42%), Gaps = 11/228 (4%)
Query: 742 TYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTP--TCQYVDCGNPGRIENGKVTLP 799
TY G Y+C GY+ +G + C G+W P CQ CG+PG G TL
Sbjct: 41 TYPEGTQAIYKCRPGYRSLGNVIMVCR-KGEWVALNPLRKCQKRPCGHPGDTPFGTFTLT 99
Query: 800 SNATF-YGATAFYQCDENWELEGVIR-RMCQENGTWSLEPPICKEITCPDPSA--QIKAG 855
F YG A Y C+E ++L G I R C +G W+ + PIC+ + C +A K
Sbjct: 100 GGNVFEYGVKAVYTCNEGYQLLGEINYRECDTDG-WTNDIPICEVVKCLPVTAPENGKIV 158
Query: 856 SGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIEN 915
S + G + C GY ++G + C G W+ P C+ I C+SP ++ N
Sbjct: 159 SSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCSDDGFWSKEKPKCVEISCKSP-DVIN 217
Query: 916 GKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
G + +Y C Y+ C + G W PSCE
Sbjct: 218 GSPISQKIIYKENERFQYKCNMGYEYSERGDAVCTESG-WR-PLPSCE 263
Score = 101 bits (241), Expect = 2e-20
Identities = 84/320 (26%), Positives = 123/320 (38%), Gaps = 23/320 (7%)
Query: 406 CKYVNCGGLTPIEDGDV---ALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGE 462
C +C L P + ++ + D G +A+Y CR + +GN C +G W
Sbjct: 16 CVAEDCNELPPRRNTEILTGSWSDQTYPEGTQAIYKCRPGYRSLGNVIMVCR-KGEWVAL 74
Query: 463 AP--RCLFDWCPDPPAVSNASVTVNGHKA---GSLASYTCENGHILSGSTSVT-CTLGGA 516
P +C C P + T+ G G A YTC G+ L G + C G
Sbjct: 75 NPLRKCQKRPCGHPGDTPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYRECDTDG- 133
Query: 517 WSGVPPSCKYVNCGTPTIHKGSFVLINGTTT-----YGSIAQFTCEPDYWLNGAEELVCN 571
W+ P C+ V C T + ++ + +G +F C Y + G EE+ C+
Sbjct: 134 WTNDIPICEVVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCS 193
Query: 572 RDGKWSYDIPSCELTSCPEPEVPSGG-YMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQ 630
DG WS + P C SC P+V +G + Y + + C G++ + VC +
Sbjct: 194 DDGFWSKEKPKCVEISCKSPDVINGSPISQKIIYKENERFQYKCNMGYEYSERGDAVCTE 253
Query: 631 DGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTN-YRLVGPVRRTCT 689
G W P+CE C P +P G L G I Y C Y CT
Sbjct: 254 SG-WR-PLPSCEEKSCDN-PYIPNGDYSPLRIKHRTGDEITYQCRNGFYPATRGNTAKCT 310
Query: 690 EEFQWSDSSPRCEEIRCSDP 709
W +PRC C P
Sbjct: 311 ST-GWI-PAPRCTLKPCDYP 328
Score = 94.3 bits (224), Expect = 2e-18
Identities = 86/337 (25%), Positives = 126/337 (37%), Gaps = 43/337 (12%)
Query: 641 CEYIDCGKLPTLPYGTMELLNG-----TTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWS 695
C DC +LP P E+L G T G+ Y C YR +G V C + +W
Sbjct: 16 CVAEDCNELP--PRRNTEILTGSWSDQTYPEGTQAIYKCRPGYRSLGNVIMVCRKG-EWV 72
Query: 696 DSSP--RCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRC 753
+P +C++ C P ++TG GN + G Y C
Sbjct: 73 ALNPLRKCQKRPCGHPGDTPFGTFTLTG------------------GNVFEYGVKAVYTC 114
Query: 754 EKGYKVIGE-SLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTL----PSNATFYGAT 808
+GY+++GE + C+ +G W+ P C+ V C ENGK+ P +G
Sbjct: 115 NEGYQLLGEINYRECDTDG-WTNDIPICEVVKCLPVTAPENGKIVSSAMEPDREYHFGQA 173
Query: 809 AFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIG 868
+ C+ +++EG C ++G WS E P C EI+C P + ++
Sbjct: 174 VRFVCNSGYKIEGDEEMHCSDDGFWSKEKPKCVEISCKSPDVINGSPISQKIIYKE---N 230
Query: 869 GEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFG 928
Y+C GY C G W +P C C +P I NG G
Sbjct: 231 ERFQYKCNMGYEYSERGDAVCTESG-WR-PLPSCEEKSCDNP-YIPNGDYSPLRIKHRTG 287
Query: 929 SSVEYYCLSQ-YQRVGPFLRKCLDDGRWSGEEPSCEL 964
+ Y C + Y KC G W P C L
Sbjct: 288 DEITYQCRNGFYPATRGNTAKCTSTG-WI-PAPRCTL 322
Score = 79.8 bits (188), Expect = 5e-14
Identities = 78/312 (25%), Positives = 126/312 (40%), Gaps = 27/312 (8%)
Query: 345 ICQYLPPTCGSPDKLLNTTILGN-DYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAP 403
+ + LP T K++++ + + +Y G + + C G+ + GD+ HC DGFWS
Sbjct: 143 VVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCSDDGFWSKEK 202
Query: 404 PSCKYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEA 463
P C ++C I ++ R Y C + + C + G W
Sbjct: 203 PKCVEISCKSPDVINGSPISQ-KIIYKENERFQYKCNMGYEYSERGDAVCTESG-W-RPL 259
Query: 464 PRCLFDWCPDPPAVSNA--SVTVNGHKAGSLASYTCENG-HILSGSTSVTCTLGGAWSGV 520
P C C D P + N S H+ G +Y C NG + + + CT G W +
Sbjct: 260 PSCEEKSC-DNPYIPNGDYSPLRIKHRTGDEITYQCRNGFYPATRGNTAKCTSTG-W--I 315
Query: 521 P-PSCKYVNCGTPTIHKGSFVLINGTTTY-----GSIAQFTCEPDYWL-NGA--EELVCN 571
P P C C P I G N Y G + C+ + +G+ + + C
Sbjct: 316 PAPRCTLKPCDYPDIKHGGLYHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDHIHCT 375
Query: 572 RDGKWSYDIPSCELTSCPEPEVPSGGYMEAFDYYVH-STINFHCEAGHKL-IGEPNLVCQ 629
+DG WS +P C L C P + +G +V +I+ C G+ L + + C
Sbjct: 376 QDG-WSPAVP-C-LRKCYFPYLENGYNQNYGRKFVQGKSIDVACHPGYALPKAQTTVTCM 432
Query: 630 QDGEWSGDSPTC 641
++G WS +P C
Sbjct: 433 ENG-WS-PTPRC 442
Score = 45.6 bits (103), Expect = 0.001
Identities = 23/58 (39%), Positives = 28/58 (48%), Gaps = 2/58 (3%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFG-ARQRECTLRGDWTLEPPFC 58
CGHP P ++ G AVY C+EGY+L G REC G WT + P C
Sbjct: 85 CGHPGDTPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYRECDTDG-WTNDIPIC 141
>BC037285-1|AAH37285.1| 449|Homo sapiens complement factor H
protein.
Length = 449
Score = 117 bits (281), Expect = 3e-25
Identities = 103/375 (27%), Positives = 151/375 (40%), Gaps = 31/375 (8%)
Query: 346 CQYLPPTCGSP-DKLLNTTIL--GNDYDVGSRIVYKCPEGHMLLGD-KSRHCKKDGFWSG 401
CQ P CG P D T L GN ++ G + VY C EG+ LLG+ R C DG W+
Sbjct: 80 CQKRP--CGHPGDTPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYRECDTDG-WTN 136
Query: 402 APPSCKYVNCGGLTPIEDGDV---ALIDNRTTHGARAL-YSCRENFTLVGNPERTCGDEG 457
P C+ V C +T E+G + A+ +R H +A+ + C + + G+ E C D+G
Sbjct: 137 DIPICEVVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCSDDG 196
Query: 458 IWDGEAPRCLFDWCPDPPAVSNASVTVN-GHKAGSLASYTCENGHILSGSTSVTCTLGGA 516
W E P+C+ C P ++ + ++ +K Y C G+ S CT G
Sbjct: 197 FWSKEKPKCVEISCKSPDVINGSPISQKIIYKENERFQYKCNMGYEYSERGDAVCTESG- 255
Query: 517 WSGVPPSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYW-LNGAEELVCNRDGK 575
W + PSC+ +C P I G + + G + C ++ C G
Sbjct: 256 WRPL-PSCEEKSCDNPYIPNGDYSPLRIKHRTGDEITYQCRNGFYPATRGNTAKCTSTG- 313
Query: 576 WSYDIPSCELTSCPEPEVPSGG-YME-----AFDYYVHSTINFHCEAGHKLIGE---PNL 626
W P C L C P++ GG Y E F V +++C+ + ++
Sbjct: 314 W-IPAPRCTLKPCDYPDIKHGGLYHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDHI 372
Query: 627 VCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRR 686
C QDG WS P C P L G + G I +C Y L
Sbjct: 373 HCTQDG-WSPAVPCLR--KC-YFPYLENGYNQNYGRKFVQGKSIDVACHPGYALPKAQTT 428
Query: 687 TCTEEFQWSDSSPRC 701
E WS +PRC
Sbjct: 429 VTCMENGWS-PTPRC 442
Score = 109 bits (261), Expect = 7e-23
Identities = 111/450 (24%), Positives = 171/450 (38%), Gaps = 43/450 (9%)
Query: 346 CQYLPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPP- 404
C LPP + ++L + Y G++ +YKC G+ LG+ C+K G W P
Sbjct: 21 CNELPPRRNT--EILTGSWSDQTYPEGTQAIYKCRPGYRSLGNVIMVCRK-GEWVALNPL 77
Query: 405 -SCKYVNCG--GLTPIEDGDVALI-DNRTTHGARALYSCRENFTLVGNPE-RTCGDEGIW 459
C+ CG G TP G L N +G +A+Y+C E + L+G R C +G W
Sbjct: 78 RKCQKRPCGHPGDTPF--GTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYRECDTDG-W 134
Query: 460 DGEAPRCLFDWCPDPPAVSNASVTVNG------HKAGSLASYTCENGHILSGSTSVTCTL 513
+ P C C A N + + + G + C +G+ + G + C+
Sbjct: 135 TNDIPICEVVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCSD 194
Query: 514 GGAWSGVPPSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRD 573
G WS P C ++C +P + GS + Q+ C Y + + VC
Sbjct: 195 DGFWSKEKPKCVEISCKSPDVINGSPISQKIIYKENERFQYKCNMGYEYSERGDAVCTES 254
Query: 574 GKWSYDIPSCELTSCPEPEVPSGGYME-AFDYYVHSTINFHCEAGHKLIGEPNLV-CQQD 631
G W +PSCE SC P +P+G Y + I + C G N C
Sbjct: 255 G-WR-PLPSCEEKSCDNPYIPNGDYSPLRIKHRTGDEITYQCRNGFYPATRGNTAKCTST 312
Query: 632 GEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEE 691
G W +P C C P + +G + N V + Y C E
Sbjct: 313 G-WI-PAPRCTLKPC-DYPDIKHGGLYHENMRRPYFPVAVGKYYSYY---------CDEH 360
Query: 692 FQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKY 751
F+ + S + I C+ + R + N++ G + G +
Sbjct: 361 FE-TPSGSYWDHIHCT-----QDGWSPAVPCLRKCYFPYLENGYNQNYGRKFVQGKSIDV 414
Query: 752 RCEKGYKV-IGESLSTCEDNGQWSGTTPTC 780
C GY + ++ TC +NG WS TP C
Sbjct: 415 ACHPGYALPKAQTTVTCMENG-WS-PTPRC 442
Score = 107 bits (256), Expect = 3e-22
Identities = 100/366 (27%), Positives = 148/366 (40%), Gaps = 48/366 (13%)
Query: 612 FHCEAGHKLIGEPNLVCQQDGEWSGDSPT--CEYIDCGKLPTLPYGTMELLNGTT-HLGS 668
+ C G++ +G +VC++ GEW +P C+ CG P+GT L G G
Sbjct: 50 YKCRPGYRSLGNVIMVCRK-GEWVALNPLRKCQKRPCGHPGDTPFGTFTLTGGNVFEYGV 108
Query: 669 VIQYSCTTNYRLVGPVR-RTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHG 727
Y+C Y+L+G + R C + W++ P CE ++C P+ A ++ V
Sbjct: 109 KAVYTCNEGYQLLGEINYRECDTD-GWTNDIPICEVVKCL-PVTAPENGKIV-------- 158
Query: 728 HTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGN 787
S + Y G V++ C GYK+ G+ C D+G WS P C + C +
Sbjct: 159 ------SSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCSDDGFWSKEKPKCVEISCKS 212
Query: 788 PGRIENG----KVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEI 843
P I K+ N F Y+C+ +E +C E+G L P C+E
Sbjct: 213 PDVINGSPISQKIIYKENERFQ-----YKCNMGYEYSERGDAVCTESGWRPL--PSCEEK 265
Query: 844 TCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERG-YNLKGHQTRTCISKGQWNGTVPVC 902
+C +P S L + T G E YQC G Y T C S G W P C
Sbjct: 266 SCDNPYIPNGDYSPLRIKHRT---GDEITYQCRNGFYPATRGNTAKCTSTG-WI-PAPRC 320
Query: 903 IPIDCRSPGNIENGKIVISNGSTLF-----GSSVEYYCLSQYQR-VGPFLR--KCLDDGR 954
C P +I++G + N + G YYC ++ G + C DG
Sbjct: 321 TLKPCDYP-DIKHGGLYHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDHIHCTQDG- 378
Query: 955 WSGEEP 960
WS P
Sbjct: 379 WSPAVP 384
Score = 104 bits (249), Expect = 2e-21
Identities = 68/228 (29%), Positives = 97/228 (42%), Gaps = 11/228 (4%)
Query: 742 TYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTP--TCQYVDCGNPGRIENGKVTLP 799
TY G Y+C GY+ +G + C G+W P CQ CG+PG G TL
Sbjct: 41 TYPEGTQAIYKCRPGYRSLGNVIMVCR-KGEWVALNPLRKCQKRPCGHPGDTPFGTFTLT 99
Query: 800 SNATF-YGATAFYQCDENWELEGVIR-RMCQENGTWSLEPPICKEITCPDPSA--QIKAG 855
F YG A Y C+E ++L G I R C +G W+ + PIC+ + C +A K
Sbjct: 100 GGNVFEYGVKAVYTCNEGYQLLGEINYRECDTDG-WTNDIPICEVVKCLPVTAPENGKIV 158
Query: 856 SGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIEN 915
S + G + C GY ++G + C G W+ P C+ I C+SP ++ N
Sbjct: 159 SSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCSDDGFWSKEKPKCVEISCKSP-DVIN 217
Query: 916 GKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
G + +Y C Y+ C + G W PSCE
Sbjct: 218 GSPISQKIIYKENERFQYKCNMGYEYSERGDAVCTESG-WR-PLPSCE 263
Score = 101 bits (241), Expect = 2e-20
Identities = 84/320 (26%), Positives = 123/320 (38%), Gaps = 23/320 (7%)
Query: 406 CKYVNCGGLTPIEDGDV---ALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGE 462
C +C L P + ++ + D G +A+Y CR + +GN C +G W
Sbjct: 16 CVAEDCNELPPRRNTEILTGSWSDQTYPEGTQAIYKCRPGYRSLGNVIMVCR-KGEWVAL 74
Query: 463 AP--RCLFDWCPDPPAVSNASVTVNGHKA---GSLASYTCENGHILSGSTSVT-CTLGGA 516
P +C C P + T+ G G A YTC G+ L G + C G
Sbjct: 75 NPLRKCQKRPCGHPGDTPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYRECDTDG- 133
Query: 517 WSGVPPSCKYVNCGTPTIHKGSFVLINGTTT-----YGSIAQFTCEPDYWLNGAEELVCN 571
W+ P C+ V C T + ++ + +G +F C Y + G EE+ C+
Sbjct: 134 WTNDIPICEVVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCS 193
Query: 572 RDGKWSYDIPSCELTSCPEPEVPSGG-YMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQ 630
DG WS + P C SC P+V +G + Y + + C G++ + VC +
Sbjct: 194 DDGFWSKEKPKCVEISCKSPDVINGSPISQKIIYKENERFQYKCNMGYEYSERGDAVCTE 253
Query: 631 DGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTN-YRLVGPVRRTCT 689
G W P+CE C P +P G L G I Y C Y CT
Sbjct: 254 SG-WR-PLPSCEEKSCDN-PYIPNGDYSPLRIKHRTGDEITYQCRNGFYPATRGNTAKCT 310
Query: 690 EEFQWSDSSPRCEEIRCSDP 709
W +PRC C P
Sbjct: 311 ST-GWI-PAPRCTLKPCDYP 328
Score = 94.3 bits (224), Expect = 2e-18
Identities = 86/337 (25%), Positives = 126/337 (37%), Gaps = 43/337 (12%)
Query: 641 CEYIDCGKLPTLPYGTMELLNG-----TTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWS 695
C DC +LP P E+L G T G+ Y C YR +G V C + +W
Sbjct: 16 CVAEDCNELP--PRRNTEILTGSWSDQTYPEGTQAIYKCRPGYRSLGNVIMVCRKG-EWV 72
Query: 696 DSSP--RCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRC 753
+P +C++ C P ++TG GN + G Y C
Sbjct: 73 ALNPLRKCQKRPCGHPGDTPFGTFTLTG------------------GNVFEYGVKAVYTC 114
Query: 754 EKGYKVIGE-SLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTL----PSNATFYGAT 808
+GY+++GE + C+ +G W+ P C+ V C ENGK+ P +G
Sbjct: 115 NEGYQLLGEINYRECDTDG-WTNDIPICEVVKCLPVTAPENGKIVSSAMEPDREYHFGQA 173
Query: 809 AFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIG 868
+ C+ +++EG C ++G WS E P C EI+C P + ++
Sbjct: 174 VRFVCNSGYKIEGDEEMHCSDDGFWSKEKPKCVEISCKSPDVINGSPISQKIIYKE---N 230
Query: 869 GEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFG 928
Y+C GY C G W +P C C +P I NG G
Sbjct: 231 ERFQYKCNMGYEYSERGDAVCTESG-WR-PLPSCEEKSCDNP-YIPNGDYSPLRIKHRTG 287
Query: 929 SSVEYYCLSQ-YQRVGPFLRKCLDDGRWSGEEPSCEL 964
+ Y C + Y KC G W P C L
Sbjct: 288 DEITYQCRNGFYPATRGNTAKCTSTG-WI-PAPRCTL 322
Score = 79.8 bits (188), Expect = 5e-14
Identities = 78/312 (25%), Positives = 126/312 (40%), Gaps = 27/312 (8%)
Query: 345 ICQYLPPTCGSPDKLLNTTILGN-DYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAP 403
+ + LP T K++++ + + +Y G + + C G+ + GD+ HC DGFWS
Sbjct: 143 VVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCSDDGFWSKEK 202
Query: 404 PSCKYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEA 463
P C ++C I ++ R Y C + + C + G W
Sbjct: 203 PKCVEISCKSPDVINGSPISQ-KIIYKENERFQYKCNMGYEYSERGDAVCTESG-W-RPL 259
Query: 464 PRCLFDWCPDPPAVSNA--SVTVNGHKAGSLASYTCENG-HILSGSTSVTCTLGGAWSGV 520
P C C D P + N S H+ G +Y C NG + + + CT G W +
Sbjct: 260 PSCEEKSC-DNPYIPNGDYSPLRIKHRTGDEITYQCRNGFYPATRGNTAKCTSTG-W--I 315
Query: 521 P-PSCKYVNCGTPTIHKGSFVLINGTTTY-----GSIAQFTCEPDYWL-NGA--EELVCN 571
P P C C P I G N Y G + C+ + +G+ + + C
Sbjct: 316 PAPRCTLKPCDYPDIKHGGLYHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDHIHCT 375
Query: 572 RDGKWSYDIPSCELTSCPEPEVPSGGYMEAFDYYVH-STINFHCEAGHKL-IGEPNLVCQ 629
+DG WS +P C L C P + +G +V +I+ C G+ L + + C
Sbjct: 376 QDG-WSPAVP-C-LRKCYFPYLENGYNQNYGRKFVQGKSIDVACHPGYALPKAQTTVTCM 432
Query: 630 QDGEWSGDSPTC 641
++G WS +P C
Sbjct: 433 ENG-WS-PTPRC 442
Score = 45.6 bits (103), Expect = 0.001
Identities = 23/58 (39%), Positives = 28/58 (48%), Gaps = 2/58 (3%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFG-ARQRECTLRGDWTLEPPFC 58
CGHP P ++ G AVY C+EGY+L G REC G WT + P C
Sbjct: 85 CGHPGDTPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYRECDTDG-WTNDIPIC 141
>BC111773-1|AAI11774.1| 569|Homo sapiens complement factor
H-related 5 protein.
Length = 569
Score = 113 bits (273), Expect = 2e-24
Identities = 138/556 (24%), Positives = 222/556 (39%), Gaps = 68/556 (12%)
Query: 437 YSCRENFTLVGNP---ERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNG--HKAGS 491
YSC NF TC +EG W P+CL C P V N +G H G
Sbjct: 53 YSCEYNFVSPSKSFWTRITCTEEG-WS-PTPKCL-RMCSFP-FVKNGHSESSGLIHLEGD 108
Query: 492 LASYTCENGHILSGST-SVTCTLGGAWSGVPPSCKYVN--CGTPTIHKGSFVLINGTT-T 547
C G+ L + +++C G WS PP C + C P + +
Sbjct: 109 TVQIICNTGYSLQNNEKNISCVERG-WS-TPPICSFTKGECHVPILEANVDAQPKKESYK 166
Query: 548 YGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSC--ELTSC-PEPEVPSGGYMEAF-- 602
G + +F+C + G++ + C + G WS + P+C ++ SC P P++ +G E
Sbjct: 167 VGDVLKFSCRKNLIRVGSDSVQCYQFG-WSPNFPTCKGQVRSCGPPPQLSNGEVKEIRKE 225
Query: 603 DYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTC--EYIDCGKLPTLPYGTMELL 660
+Y + + + C + G + C DGEW+ PTC + CG +P L YG ++
Sbjct: 226 EYGHNEVVEYDCNPNFIINGPKKIQCV-DGEWT-TLPTCVEQVKTCGYIPELEYGYVQPS 283
Query: 661 NGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEI----RCSDPIVAEKSI 716
G ++ +C Y ++G TC W++ P C RC V K++
Sbjct: 284 VPPYQHGVSVEVNCRNEYAMIGNNMITCINGI-WTEL-PMCVATHQLKRCKIAGVNIKTL 341
Query: 717 VSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGT 776
+ ++G + +H ++ IR YR + +YR S C NG+W+
Sbjct: 342 LKLSGKEFNH-NSRIR----------YRCSDIFRYRH-----------SVCI-NGKWNPE 378
Query: 777 TPTCQYVD--CGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWS 834
+ + C P +I N + + G C EN+ L +C++ G W
Sbjct: 379 VDCTEKREQFCPPPPQIPNAQNMTTTVNYQDGEKVAVLCKENYLLPEAKEIVCKD-GRWQ 437
Query: 835 LEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQ 894
P + P I G S G Y+C+ Y L+G T TC +K Q
Sbjct: 438 SLPRCVESTAYCGPPPSINNGDTTSFPLSVYPPGSTVTYRCQSFYKLQGSVTVTCRNK-Q 496
Query: 895 WNGTVPVCIPIDCRSPGNIENGKIVIS--NGSTLF---GSSVEYYCLSQYQRV--GPFLR 947
W+ P C+ S N+ I + N L+ G +VE+ C ++ + P R
Sbjct: 497 WS-EPPRCLDPCVVSEENMNKNNIQLKWRNDGKLYAKTGDAVEFQCKFPHKAMISSPPFR 555
Query: 948 KCLDDGRWSGEEPSCE 963
+G++ E P CE
Sbjct: 556 AICQEGKF--EYPICE 569
Score = 88.6 bits (210), Expect = 1e-16
Identities = 93/377 (24%), Positives = 155/377 (41%), Gaps = 32/377 (8%)
Query: 345 ICQYLPPTCGSP--DKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGA 402
IC + C P + ++ Y VG + + C + + +G S C + G WS
Sbjct: 139 ICSFTKGECHVPILEANVDAQPKKESYKVGDVLKFSCRKNLIRVGSDSVQCYQFG-WSPN 197
Query: 403 PPSCK--YVNCGGLTPIEDGDVALIDNRTT-HGARALYSCRENFTLVGNPERTCGDEGIW 459
P+CK +CG + +G+V I H Y C NF + G + C D G W
Sbjct: 198 FPTCKGQVRSCGPPPQLSNGEVKEIRKEEYGHNEVVEYDCNPNFIINGPKKIQCVD-GEW 256
Query: 460 DGEAPRCL--FDWCPDPPAVSNASV--TVNGHKAGSLASYTCENGHILSGSTSVTCTLGG 515
P C+ C P + V +V ++ G C N + + G+ +TC + G
Sbjct: 257 T-TLPTCVEQVKTCGYIPELEYGYVQPSVPPYQHGVSVEVNCRNEYAMIGNNMITC-ING 314
Query: 516 AWSGVP---PSCKYVNCGTPTIHKGSFVLINGTT-TYGSIAQFTCEPDYWLNGAEELVCN 571
W+ +P + + C ++ + + ++G + S ++ C + + VC
Sbjct: 315 IWTELPMCVATHQLKRCKIAGVNIKTLLKLSGKEFNHNSRIRYRCSDIFRYRHS---VCI 371
Query: 572 RDGKWSYDIPSCELTS--CPEP-EVPSGGYMEA-FDYYVHSTINFHCEAGHKLIGEPNLV 627
+GKW+ ++ E CP P ++P+ M +Y + C+ + L +V
Sbjct: 372 -NGKWNPEVDCTEKREQFCPPPPQIPNAQNMTTTVNYQDGEKVAVLCKENYLLPEAKEIV 430
Query: 628 CQQDGEWSGDSPTC--EYIDCGKLPTLPYG-TMELLNGTTHLGSVIQYSCTTNYRLVGPV 684
C+ DG W P C CG P++ G T GS + Y C + Y+L G V
Sbjct: 431 CK-DGRWQS-LPRCVESTAYCGPPPSINNGDTTSFPLSVYPPGSTVTYRCQSFYKLQGSV 488
Query: 685 RRTCTEEFQWSDSSPRC 701
TC + QWS+ PRC
Sbjct: 489 TVTCRNK-QWSE-PPRC 503
>AL353809-1|CAH72548.1| 593|Homo sapiens complement factor
H-related 5 protein.
Length = 593
Score = 113 bits (273), Expect = 2e-24
Identities = 138/556 (24%), Positives = 222/556 (39%), Gaps = 68/556 (12%)
Query: 437 YSCRENFTLVGNP---ERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNG--HKAGS 491
YSC NF TC +EG W P+CL C P V N +G H G
Sbjct: 77 YSCEYNFVSPSKSFWTRITCTEEG-WS-PTPKCL-RMCSFP-FVKNGHSESSGLIHLEGD 132
Query: 492 LASYTCENGHILSGST-SVTCTLGGAWSGVPPSCKYVN--CGTPTIHKGSFVLINGTT-T 547
C G+ L + +++C G WS PP C + C P + +
Sbjct: 133 TVQIICNTGYSLQNNEKNISCVERG-WS-TPPICSFTKGECHVPILEANVDAQPKKESYK 190
Query: 548 YGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSC--ELTSC-PEPEVPSGGYMEAF-- 602
G + +F+C + G++ + C + G WS + P+C ++ SC P P++ +G E
Sbjct: 191 VGDVLKFSCRKNLIRVGSDSVQCYQFG-WSPNFPTCKGQVRSCGPPPQLSNGEVKEIRKE 249
Query: 603 DYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTC--EYIDCGKLPTLPYGTMELL 660
+Y + + + C + G + C DGEW+ PTC + CG +P L YG ++
Sbjct: 250 EYGHNEVVEYDCNPNFIINGPKKIQCV-DGEWT-TLPTCVEQVKTCGYIPELEYGYVQPS 307
Query: 661 NGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEI----RCSDPIVAEKSI 716
G ++ +C Y ++G TC W++ P C RC V K++
Sbjct: 308 VPPYQHGVSVEVNCRNEYAMIGNNMITCINGI-WTEL-PMCVATHQLKRCKIAGVNIKTL 365
Query: 717 VSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGT 776
+ ++G + +H ++ IR YR + +YR S C NG+W+
Sbjct: 366 LKLSGKEFNH-NSRIR----------YRCSDIFRYRH-----------SVCI-NGKWNPE 402
Query: 777 TPTCQYVD--CGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWS 834
+ + C P +I N + + G C EN+ L +C++ G W
Sbjct: 403 VDCTEKREQFCPPPPQIPNAQNMTTTVNYQDGEKVAVLCKENYLLPEAKEIVCKD-GRWQ 461
Query: 835 LEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQ 894
P + P I G S G Y+C+ Y L+G T TC +K Q
Sbjct: 462 SLPRCVESTAYCGPPPSINNGDTTSFPLSVYPPGSTVTYRCQSFYKLQGSVTVTCRNK-Q 520
Query: 895 WNGTVPVCIPIDCRSPGNIENGKIVIS--NGSTLF---GSSVEYYCLSQYQRV--GPFLR 947
W+ P C+ S N+ I + N L+ G +VE+ C ++ + P R
Sbjct: 521 WS-EPPRCLDPCVVSEENMNKNNIQLKWRNDGKLYAKTGDAVEFQCKFPHKAMISSPPFR 579
Query: 948 KCLDDGRWSGEEPSCE 963
+G++ E P CE
Sbjct: 580 AICQEGKF--EYPICE 593
Score = 88.6 bits (210), Expect = 1e-16
Identities = 93/377 (24%), Positives = 155/377 (41%), Gaps = 32/377 (8%)
Query: 345 ICQYLPPTCGSP--DKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGA 402
IC + C P + ++ Y VG + + C + + +G S C + G WS
Sbjct: 163 ICSFTKGECHVPILEANVDAQPKKESYKVGDVLKFSCRKNLIRVGSDSVQCYQFG-WSPN 221
Query: 403 PPSCK--YVNCGGLTPIEDGDVALIDNRTT-HGARALYSCRENFTLVGNPERTCGDEGIW 459
P+CK +CG + +G+V I H Y C NF + G + C D G W
Sbjct: 222 FPTCKGQVRSCGPPPQLSNGEVKEIRKEEYGHNEVVEYDCNPNFIINGPKKIQCVD-GEW 280
Query: 460 DGEAPRCL--FDWCPDPPAVSNASV--TVNGHKAGSLASYTCENGHILSGSTSVTCTLGG 515
P C+ C P + V +V ++ G C N + + G+ +TC + G
Sbjct: 281 T-TLPTCVEQVKTCGYIPELEYGYVQPSVPPYQHGVSVEVNCRNEYAMIGNNMITC-ING 338
Query: 516 AWSGVP---PSCKYVNCGTPTIHKGSFVLINGTT-TYGSIAQFTCEPDYWLNGAEELVCN 571
W+ +P + + C ++ + + ++G + S ++ C + + VC
Sbjct: 339 IWTELPMCVATHQLKRCKIAGVNIKTLLKLSGKEFNHNSRIRYRCSDIFRYRHS---VCI 395
Query: 572 RDGKWSYDIPSCELTS--CPEP-EVPSGGYMEA-FDYYVHSTINFHCEAGHKLIGEPNLV 627
+GKW+ ++ E CP P ++P+ M +Y + C+ + L +V
Sbjct: 396 -NGKWNPEVDCTEKREQFCPPPPQIPNAQNMTTTVNYQDGEKVAVLCKENYLLPEAKEIV 454
Query: 628 CQQDGEWSGDSPTC--EYIDCGKLPTLPYG-TMELLNGTTHLGSVIQYSCTTNYRLVGPV 684
C+ DG W P C CG P++ G T GS + Y C + Y+L G V
Sbjct: 455 CK-DGRWQS-LPRCVESTAYCGPPPSINNGDTTSFPLSVYPPGSTVTYRCQSFYKLQGSV 512
Query: 685 RRTCTEEFQWSDSSPRC 701
TC + QWS+ PRC
Sbjct: 513 TVTCRNK-QWSE-PPRC 527
>AL139418-4|CAI21982.1| 593|Homo sapiens complement factor
H-related 5 protein.
Length = 593
Score = 113 bits (273), Expect = 2e-24
Identities = 138/556 (24%), Positives = 222/556 (39%), Gaps = 68/556 (12%)
Query: 437 YSCRENFTLVGNP---ERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNG--HKAGS 491
YSC NF TC +EG W P+CL C P V N +G H G
Sbjct: 77 YSCEYNFVSPSKSFWTRITCTEEG-WS-PTPKCL-RMCSFP-FVKNGHSESSGLIHLEGD 132
Query: 492 LASYTCENGHILSGST-SVTCTLGGAWSGVPPSCKYVN--CGTPTIHKGSFVLINGTT-T 547
C G+ L + +++C G WS PP C + C P + +
Sbjct: 133 TVQIICNTGYSLQNNEKNISCVERG-WS-TPPICSFTKGECHVPILEANVDAQPKKESYK 190
Query: 548 YGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSC--ELTSC-PEPEVPSGGYMEAF-- 602
G + +F+C + G++ + C + G WS + P+C ++ SC P P++ +G E
Sbjct: 191 VGDVLKFSCRKNLIRVGSDSVQCYQFG-WSPNFPTCKGQVRSCGPPPQLSNGEVKEIRKE 249
Query: 603 DYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTC--EYIDCGKLPTLPYGTMELL 660
+Y + + + C + G + C DGEW+ PTC + CG +P L YG ++
Sbjct: 250 EYGHNEVVEYDCNPNFIINGPKKIQCV-DGEWT-TLPTCVEQVKTCGYIPELEYGYVQPS 307
Query: 661 NGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEI----RCSDPIVAEKSI 716
G ++ +C Y ++G TC W++ P C RC V K++
Sbjct: 308 VPPYQHGVSVEVNCRNEYAMIGNNMITCINGI-WTEL-PMCVATHQLKRCKIAGVNIKTL 365
Query: 717 VSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGT 776
+ ++G + +H ++ IR YR + +YR S C NG+W+
Sbjct: 366 LKLSGKEFNH-NSRIR----------YRCSDIFRYRH-----------SVCI-NGKWNPE 402
Query: 777 TPTCQYVD--CGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWS 834
+ + C P +I N + + G C EN+ L +C++ G W
Sbjct: 403 VDCTEKREQFCPPPPQIPNAQNMTTTVNYQDGEKVAVLCKENYLLPEAKEIVCKD-GRWQ 461
Query: 835 LEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQ 894
P + P I G S G Y+C+ Y L+G T TC +K Q
Sbjct: 462 SLPRCVESTAYCGPPPSINNGDTTSFPLSVYPPGSTVTYRCQSFYKLQGSVTVTCRNK-Q 520
Query: 895 WNGTVPVCIPIDCRSPGNIENGKIVIS--NGSTLF---GSSVEYYCLSQYQRV--GPFLR 947
W+ P C+ S N+ I + N L+ G +VE+ C ++ + P R
Sbjct: 521 WS-EPPRCLDPCVVSEENMNKNNIQLKWRNDGKLYAKTGDAVEFQCKFPHKAMISSPPFR 579
Query: 948 KCLDDGRWSGEEPSCE 963
+G++ E P CE
Sbjct: 580 AICQEGKF--EYPICE 593
Score = 88.6 bits (210), Expect = 1e-16
Identities = 93/377 (24%), Positives = 155/377 (41%), Gaps = 32/377 (8%)
Query: 345 ICQYLPPTCGSP--DKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGA 402
IC + C P + ++ Y VG + + C + + +G S C + G WS
Sbjct: 163 ICSFTKGECHVPILEANVDAQPKKESYKVGDVLKFSCRKNLIRVGSDSVQCYQFG-WSPN 221
Query: 403 PPSCK--YVNCGGLTPIEDGDVALIDNRTT-HGARALYSCRENFTLVGNPERTCGDEGIW 459
P+CK +CG + +G+V I H Y C NF + G + C D G W
Sbjct: 222 FPTCKGQVRSCGPPPQLSNGEVKEIRKEEYGHNEVVEYDCNPNFIINGPKKIQCVD-GEW 280
Query: 460 DGEAPRCL--FDWCPDPPAVSNASV--TVNGHKAGSLASYTCENGHILSGSTSVTCTLGG 515
P C+ C P + V +V ++ G C N + + G+ +TC + G
Sbjct: 281 T-TLPTCVEQVKTCGYIPELEYGYVQPSVPPYQHGVSVEVNCRNEYAMIGNNMITC-ING 338
Query: 516 AWSGVP---PSCKYVNCGTPTIHKGSFVLINGTT-TYGSIAQFTCEPDYWLNGAEELVCN 571
W+ +P + + C ++ + + ++G + S ++ C + + VC
Sbjct: 339 IWTELPMCVATHQLKRCKIAGVNIKTLLKLSGKEFNHNSRIRYRCSDIFRYRHS---VCI 395
Query: 572 RDGKWSYDIPSCELTS--CPEP-EVPSGGYMEA-FDYYVHSTINFHCEAGHKLIGEPNLV 627
+GKW+ ++ E CP P ++P+ M +Y + C+ + L +V
Sbjct: 396 -NGKWNPEVDCTEKREQFCPPPPQIPNAQNMTTTVNYQDGEKVAVLCKENYLLPEAKEIV 454
Query: 628 CQQDGEWSGDSPTC--EYIDCGKLPTLPYG-TMELLNGTTHLGSVIQYSCTTNYRLVGPV 684
C+ DG W P C CG P++ G T GS + Y C + Y+L G V
Sbjct: 455 CK-DGRWQS-LPRCVESTAYCGPPPSINNGDTTSFPLSVYPPGSTVTYRCQSFYKLQGSV 512
Query: 685 RRTCTEEFQWSDSSPRC 701
TC + QWS+ PRC
Sbjct: 513 TVTCRNK-QWSE-PPRC 527
>AF295327-1|AAK15619.1| 569|Homo sapiens complement factor
H-related protein 5 protein.
Length = 569
Score = 113 bits (273), Expect = 2e-24
Identities = 138/556 (24%), Positives = 222/556 (39%), Gaps = 68/556 (12%)
Query: 437 YSCRENFTLVGNP---ERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNG--HKAGS 491
YSC NF TC +EG W P+CL C P V N +G H G
Sbjct: 53 YSCEYNFVSPSKSFWTRITCTEEG-WS-PTPKCL-RMCSFP-FVKNGHSESSGLIHLEGD 108
Query: 492 LASYTCENGHILSGST-SVTCTLGGAWSGVPPSCKYVN--CGTPTIHKGSFVLINGTT-T 547
C G+ L + +++C G WS PP C + C P + +
Sbjct: 109 TVQIICNTGYSLQNNEKNISCVERG-WS-TPPICSFTKGECHVPILEANVDAQPKKESYK 166
Query: 548 YGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSC--ELTSC-PEPEVPSGGYMEAF-- 602
G + +F+C + G++ + C + G WS + P+C ++ SC P P++ +G E
Sbjct: 167 VGDVLKFSCRKNLIRVGSDSVQCYQFG-WSPNFPTCKGQVRSCGPPPQLSNGEVKEIRKE 225
Query: 603 DYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTC--EYIDCGKLPTLPYGTMELL 660
+Y + + + C + G + C DGEW+ PTC + CG +P L YG ++
Sbjct: 226 EYGHNEVVEYDCNPNFIINGPKKIQCV-DGEWT-TLPTCVEQVKTCGYIPELEYGYVQPS 283
Query: 661 NGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEI----RCSDPIVAEKSI 716
G ++ +C Y ++G TC W++ P C RC V K++
Sbjct: 284 VPPYQHGVSVEVNCRNEYAMIGNNMITCINGI-WTEL-PMCVATHQLKRCKIAGVNIKTL 341
Query: 717 VSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGT 776
+ ++G + +H ++ IR YR + +YR S C NG+W+
Sbjct: 342 LKLSGKEFNH-NSRIR----------YRCSDIFRYRH-----------SVCI-NGKWNPE 378
Query: 777 TPTCQYVD--CGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWS 834
+ + C P +I N + + G C EN+ L +C++ G W
Sbjct: 379 VDCTEKREQFCPPPPQIPNAQNMTTTVNYQDGEKVAVLCKENYLLPEAKEIVCKD-GRWQ 437
Query: 835 LEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQ 894
P + P I G S G Y+C+ Y L+G T TC +K Q
Sbjct: 438 SLPRCVESTAYCGPPPSINNGDTTSFPLSVYPPGSTVTYRCQSFYKLQGSVTVTCRNK-Q 496
Query: 895 WNGTVPVCIPIDCRSPGNIENGKIVIS--NGSTLF---GSSVEYYCLSQYQRV--GPFLR 947
W+ P C+ S N+ I + N L+ G +VE+ C ++ + P R
Sbjct: 497 WS-EPPRCLDPCVVSEENMNKNNIQLKWRNDGKLYAKTGDAVEFQCKFPHKAMISSPPFR 555
Query: 948 KCLDDGRWSGEEPSCE 963
+G++ E P CE
Sbjct: 556 AICQEGKF--EYPICE 569
Score = 88.6 bits (210), Expect = 1e-16
Identities = 93/377 (24%), Positives = 155/377 (41%), Gaps = 32/377 (8%)
Query: 345 ICQYLPPTCGSP--DKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGA 402
IC + C P + ++ Y VG + + C + + +G S C + G WS
Sbjct: 139 ICSFTKGECHVPILEANVDAQPKKESYKVGDVLKFSCRKNLIRVGSDSVQCYQFG-WSPN 197
Query: 403 PPSCK--YVNCGGLTPIEDGDVALIDNRTT-HGARALYSCRENFTLVGNPERTCGDEGIW 459
P+CK +CG + +G+V I H Y C NF + G + C D G W
Sbjct: 198 FPTCKGQVRSCGPPPQLSNGEVKEIRKEEYGHNEVVEYDCNPNFIINGPKKIQCVD-GEW 256
Query: 460 DGEAPRCL--FDWCPDPPAVSNASV--TVNGHKAGSLASYTCENGHILSGSTSVTCTLGG 515
P C+ C P + V +V ++ G C N + + G+ +TC + G
Sbjct: 257 T-TLPTCVEQVKTCGYIPELEYGYVQPSVPPYQHGVSVEVNCRNEYAMIGNNMITC-ING 314
Query: 516 AWSGVP---PSCKYVNCGTPTIHKGSFVLINGTT-TYGSIAQFTCEPDYWLNGAEELVCN 571
W+ +P + + C ++ + + ++G + S ++ C + + VC
Sbjct: 315 IWTELPMCVATHQLKRCKIAGVNIKTLLKLSGKEFNHNSRIRYRCSDIFRYRHS---VCI 371
Query: 572 RDGKWSYDIPSCELTS--CPEP-EVPSGGYMEA-FDYYVHSTINFHCEAGHKLIGEPNLV 627
+GKW+ ++ E CP P ++P+ M +Y + C+ + L +V
Sbjct: 372 -NGKWNPEVDCTEKREQFCPPPPQIPNAQNMTTTVNYQDGEKVAVLCKENYLLPEAKEIV 430
Query: 628 CQQDGEWSGDSPTC--EYIDCGKLPTLPYG-TMELLNGTTHLGSVIQYSCTTNYRLVGPV 684
C+ DG W P C CG P++ G T GS + Y C + Y+L G V
Sbjct: 431 CK-DGRWQS-LPRCVESTAYCGPPPSINNGDTTSFPLSVYPPGSTVTYRCQSFYKLQGSV 488
Query: 685 RRTCTEEFQWSDSSPRC 701
TC + QWS+ PRC
Sbjct: 489 TVTCRNK-QWSE-PPRC 503
>AY358404-1|AAQ88770.1| 910|Homo sapiens PSK-1 protein.
Length = 910
Score = 106 bits (254), Expect = 5e-22
Identities = 73/231 (31%), Positives = 110/231 (47%), Gaps = 28/231 (12%)
Query: 646 CGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEI- 704
C +LP +G +G G+V+ Y C Y L+G TC + WS + P C++I
Sbjct: 644 CPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKIM 703
Query: 705 RCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESL 764
C+DP + ++GH RT+ D G + +G+ V+YRC GY + G ++
Sbjct: 704 TCADP------------GEIANGH---RTAS--DAG--FPVGSHVQYRCLPGYSLEGAAM 744
Query: 765 STC--EDNG--QWSGTTPTC--QYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWE 818
TC D G +WS P C +Y C NPG ENG TL + G + + C E +E
Sbjct: 745 LTCYSRDTGTPKWSDRVPKCALKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFE 804
Query: 819 LEGVIRRMCQEN--GTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSI 867
L G + C W+ +PP+CK DPS Q++ G+ L + L +
Sbjct: 805 LIGEVTITCVPGHPSQWTSQPPLCKVTQTTDPSRQLEGGNLALAILLPLGL 855
Score = 97.9 bits (233), Expect = 2e-19
Identities = 65/195 (33%), Positives = 88/195 (45%), Gaps = 16/195 (8%)
Query: 462 EAPRCLFDWCPD--PPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSG 519
E PR D CP+ PP + + G++ +Y CE G+ L GS +TC +WS
Sbjct: 637 EVPRN--DTCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSA 694
Query: 520 VPPSC-KYVNCGTP-TIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVC-NRD--- 573
PP+C K + C P I G + GS Q+ C P Y L GA L C +RD
Sbjct: 695 APPACQKIMTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGT 754
Query: 574 GKWSYDIPSCEL--TSCPEPEVPSGGYMEAF--DYYVHSTINFHCEAGHKLIGEPNLVC- 628
KWS +P C L C P VP GY + Y ++ F C G +LIGE + C
Sbjct: 755 PKWSDRVPKCALKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCV 814
Query: 629 -QQDGEWSGDSPTCE 642
+W+ P C+
Sbjct: 815 PGHPSQWTSQPPLCK 829
Score = 82.2 bits (194), Expect = 9e-15
Identities = 63/224 (28%), Positives = 95/224 (42%), Gaps = 31/224 (13%)
Query: 587 SCPEPEVPSGGYMEAF--DYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYI 644
+CPE P G+ A D + + + CE G++L+G L CQ D WS P C+ I
Sbjct: 643 TCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKI 702
Query: 645 -DCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTC----TEEFQWSDSSP 699
C + G + +GS +QY C Y L G TC T +WSD P
Sbjct: 703 MTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVP 762
Query: 700 RC--EEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGY 757
+C + C +P V E TL + + Y+ G +++ C +G+
Sbjct: 763 KCALKYEPCLNPGVPENGY-----------QTLYK--------HHYQAGESLRFFCYEGF 803
Query: 758 KVIGESLSTCEDN--GQWSGTTPTCQYVDCGNPGR-IENGKVTL 798
++IGE TC QW+ P C+ +P R +E G + L
Sbjct: 804 ELIGEVTITCVPGHPSQWTSQPPLCKVTQTTDPSRQLEGGNLAL 847
Score = 81.8 bits (193), Expect = 1e-14
Identities = 60/199 (30%), Positives = 83/199 (41%), Gaps = 16/199 (8%)
Query: 346 CQYLPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPS 405
C LPP P+ T G D G+ + Y+C G+ LLG C+ D WS APP+
Sbjct: 644 CPELPP----PEWGWRTASHG-DLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPA 698
Query: 406 C-KYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTC--GDEGI--WD 460
C K + C I +G D G+ Y C ++L G TC D G W
Sbjct: 699 CQKIMTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWS 758
Query: 461 GEAPRCL--FDWCPDPPAVSNASVTVNGH--KAGSLASYTCENGHILSGSTSVTCTLG-- 514
P+C ++ C +P N T+ H +AG + C G L G ++TC G
Sbjct: 759 DRVPKCALKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHP 818
Query: 515 GAWSGVPPSCKYVNCGTPT 533
W+ PP CK P+
Sbjct: 819 SQWTSQPPLCKVTQTTDPS 837
Score = 81.4 bits (192), Expect = 2e-14
Identities = 49/168 (29%), Positives = 80/168 (47%), Gaps = 11/168 (6%)
Query: 806 GATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEI-TCPDPSAQIKAGSGLLVVTST 864
G YQC+ +EL G CQ + +WS PP C++I TC DP +I G +
Sbjct: 665 GTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKIMTCADPG-EIANGHRT-ASDAG 722
Query: 865 LSIGGEAHYQCERGYNLKGHQTRTCISKG----QWNGTVPVC-IPID-CRSPGNIENGKI 918
+G Y+C GY+L+G TC S+ +W+ VP C + + C +PG ENG
Sbjct: 723 FPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPKCALKYEPCLNPGVPENGYQ 782
Query: 919 VISNGSTLFGSSVEYYCLSQYQRVGPFLRKCL--DDGRWSGEEPSCEL 964
+ G S+ ++C ++ +G C+ +W+ + P C++
Sbjct: 783 TLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPLCKV 830
Score = 65.3 bits (152), Expect = 1e-09
Identities = 38/106 (35%), Positives = 45/106 (42%), Gaps = 5/106 (4%)
Query: 873 YQCERGYNLKGHQTRTCISKGQWNGTVPVCIPI-DCRSPGNIENGKIVISNGSTLFGSSV 931
YQCE GY L G TC W+ P C I C PG I NG S+ GS V
Sbjct: 670 YQCEPGYELLGSDILTCQWDLSWSAAPPACQKIMTCADPGEIANGHRTASDAGFPVGSHV 729
Query: 932 EYYCLSQYQRVGPFLRKCL--DDG--RWSGEEPSCELATNEAVDSG 973
+Y CL Y G + C D G +WS P C L ++ G
Sbjct: 730 QYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPKCALKYEPCLNPG 775
Score = 49.6 bits (113), Expect = 6e-05
Identities = 23/65 (35%), Positives = 35/65 (53%), Gaps = 3/65 (4%)
Query: 585 LTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQD--GEWSGDSPTCE 642
L SC P P+ G + D + T FHC++G++L GE L+C W+G++P+C
Sbjct: 287 LLSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSC- 345
Query: 643 YIDCG 647
CG
Sbjct: 346 MASCG 350
Score = 45.2 bits (102), Expect = 0.001
Identities = 27/89 (30%), Positives = 43/89 (48%), Gaps = 5/89 (5%)
Query: 471 CPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLG--GAWSGVPPSCKYVN 528
C PP ++ V+V G A++ C++G+ L G ++ C G +W+G PSC +
Sbjct: 290 CGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSC-MAS 348
Query: 529 CGTPTIHKGSFVLINGTTTYGSIA-QFTC 556
CG TIH + I G++ TC
Sbjct: 349 CG-GTIHNATLGRIVSPEPGGAVGPNLTC 376
Score = 41.9 bits (94), Expect = 0.012
Identities = 21/62 (33%), Positives = 32/62 (51%), Gaps = 2/62 (3%)
Query: 860 VVTSTLSIGGEAHYQCERGYNLKGHQTRTCI--SKGQWNGTVPVCIPIDCRSPGNIENGK 917
V + L GG A + C+ GY L+G +T C+ ++ WNG P C+ + N G+
Sbjct: 301 VSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCMASCGGTIHNATLGR 360
Query: 918 IV 919
IV
Sbjct: 361 IV 362
Score = 41.1 bits (92), Expect = 0.021
Identities = 22/89 (24%), Positives = 35/89 (39%), Gaps = 4/89 (4%)
Query: 8 PPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTNVAFRKP 67
PP + +++ GT+ Y+C+ GYEL G+ C W+ PP C + P
Sbjct: 649 PPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKIMTCADP 708
Query: 68 ANQSTTVRGGAAANGNDGEKTTEHDRKRC 96
+ G + G H + RC
Sbjct: 709 GE----IANGHRTASDAGFPVGSHVQYRC 733
Score = 36.3 bits (80), Expect = 0.60
Identities = 31/116 (26%), Positives = 46/116 (39%), Gaps = 7/116 (6%)
Query: 354 GSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGG 413
GSP L +L N +G V + P +LL +S + G + ++CG
Sbjct: 236 GSPG--LAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFR-IHYQAYLLSCGF 292
Query: 414 LTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTC--GDEGIWDGEAPRCL 467
GDV++ D G A + C + L G C G W+GE P C+
Sbjct: 293 PPRPAHGDVSVTDLHP--GGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCM 346
Score = 36.3 bits (80), Expect = 0.60
Identities = 18/64 (28%), Positives = 29/64 (45%), Gaps = 3/64 (4%)
Query: 352 TCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKD--GFWSGAPPSCKYV 409
+CG P + + + D G + C G+ L G+++ C W+G PSC
Sbjct: 289 SCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSC-MA 347
Query: 410 NCGG 413
+CGG
Sbjct: 348 SCGG 351
Score = 35.5 bits (78), Expect = 1.0
Identities = 20/59 (33%), Positives = 26/59 (44%), Gaps = 5/59 (8%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECT--LRGDWTLEPPFC 58
CG P P + VS+ + + G A + CD GY+L G C R W E P C
Sbjct: 290 CGFPPRPAHGDVSVTD---LHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSC 345
Score = 34.7 bits (76), Expect = 1.8
Identities = 21/61 (34%), Positives = 31/61 (50%), Gaps = 6/61 (9%)
Query: 783 VDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGT---WSLEPPI 839
+ CG P R +G V++ G TA + CD ++L+G +C NGT W+ E P
Sbjct: 288 LSCGFPPRPAHGDVSVTD--LHPGGTATFHCDSGYQLQGEETLICL-NGTRPSWNGETPS 344
Query: 840 C 840
C
Sbjct: 345 C 345
Score = 34.7 bits (76), Expect = 1.8
Identities = 19/59 (32%), Positives = 29/59 (49%), Gaps = 8/59 (13%)
Query: 746 GALVKYRCEKGYKVIGESLSTCEDNGQ--WSGTTPTCQYVDCGNPGRIEN---GKVTLP 799
G + C+ GY++ GE C + + W+G TP+C CG G I N G++ P
Sbjct: 309 GGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCM-ASCG--GTIHNATLGRIVSP 364
Score = 33.1 bits (72), Expect = 5.6
Identities = 16/42 (38%), Positives = 22/42 (52%), Gaps = 3/42 (7%)
Query: 549 GSIAQFTCEPDYWLNGAEELVCNRDGK--WSYDIPSCELTSC 588
G A F C+ Y L G E L+C + W+ + PSC + SC
Sbjct: 309 GGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSC-MASC 349
Score = 32.7 bits (71), Expect = 7.4
Identities = 19/72 (26%), Positives = 33/72 (45%), Gaps = 4/72 (5%)
Query: 905 IDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGR--WSGEEPSC 962
+ C P +G + +++ G + ++C S YQ G CL+ R W+GE PSC
Sbjct: 288 LSCGFPPRPAHGDVSVTDLHP--GGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSC 345
Query: 963 ELATNEAVDSGT 974
+ + + T
Sbjct: 346 MASCGGTIHNAT 357
>AJ245822-1|CAB57952.1| 840|Homo sapiens type I transmembrane
receptor protein.
Length = 840
Score = 106 bits (254), Expect = 5e-22
Identities = 73/231 (31%), Positives = 110/231 (47%), Gaps = 28/231 (12%)
Query: 646 CGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEI- 704
C +LP +G +G G+V+ Y C Y L+G TC + WS + P C++I
Sbjct: 574 CPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKIM 633
Query: 705 RCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESL 764
C+DP + ++GH RT+ D G + +G+ V+YRC GY + G ++
Sbjct: 634 TCADP------------GEIANGH---RTAS--DAG--FPVGSHVQYRCLPGYSLEGAAM 674
Query: 765 STC--EDNG--QWSGTTPTC--QYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWE 818
TC D G +WS P C +Y C NPG ENG TL + G + + C E +E
Sbjct: 675 LTCYSRDTGTPKWSDRVPKCALKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFE 734
Query: 819 LEGVIRRMCQEN--GTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSI 867
L G + C W+ +PP+CK DPS Q++ G+ L + L +
Sbjct: 735 LIGEVTITCVPGHPSQWTSQPPLCKVTQTTDPSRQLEGGNLALAILLPLGL 785
Score = 97.9 bits (233), Expect = 2e-19
Identities = 65/195 (33%), Positives = 88/195 (45%), Gaps = 16/195 (8%)
Query: 462 EAPRCLFDWCPD--PPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSG 519
E PR D CP+ PP + + G++ +Y CE G+ L GS +TC +WS
Sbjct: 567 EVPRN--DTCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSA 624
Query: 520 VPPSC-KYVNCGTP-TIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVC-NRD--- 573
PP+C K + C P I G + GS Q+ C P Y L GA L C +RD
Sbjct: 625 APPACQKIMTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGT 684
Query: 574 GKWSYDIPSCEL--TSCPEPEVPSGGYMEAF--DYYVHSTINFHCEAGHKLIGEPNLVC- 628
KWS +P C L C P VP GY + Y ++ F C G +LIGE + C
Sbjct: 685 PKWSDRVPKCALKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCV 744
Query: 629 -QQDGEWSGDSPTCE 642
+W+ P C+
Sbjct: 745 PGHPSQWTSQPPLCK 759
Score = 82.2 bits (194), Expect = 9e-15
Identities = 63/224 (28%), Positives = 95/224 (42%), Gaps = 31/224 (13%)
Query: 587 SCPEPEVPSGGYMEAF--DYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYI 644
+CPE P G+ A D + + + CE G++L+G L CQ D WS P C+ I
Sbjct: 573 TCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKI 632
Query: 645 -DCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTC----TEEFQWSDSSP 699
C + G + +GS +QY C Y L G TC T +WSD P
Sbjct: 633 MTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVP 692
Query: 700 RC--EEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGY 757
+C + C +P V E TL + + Y+ G +++ C +G+
Sbjct: 693 KCALKYEPCLNPGVPENGY-----------QTLYK--------HHYQAGESLRFFCYEGF 733
Query: 758 KVIGESLSTCEDN--GQWSGTTPTCQYVDCGNPGR-IENGKVTL 798
++IGE TC QW+ P C+ +P R +E G + L
Sbjct: 734 ELIGEVTITCVPGHPSQWTSQPPLCKVTQTTDPSRQLEGGNLAL 777
Score = 81.8 bits (193), Expect = 1e-14
Identities = 60/199 (30%), Positives = 83/199 (41%), Gaps = 16/199 (8%)
Query: 346 CQYLPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPS 405
C LPP P+ T G D G+ + Y+C G+ LLG C+ D WS APP+
Sbjct: 574 CPELPP----PEWGWRTASHG-DLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPA 628
Query: 406 C-KYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTC--GDEGI--WD 460
C K + C I +G D G+ Y C ++L G TC D G W
Sbjct: 629 CQKIMTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWS 688
Query: 461 GEAPRCL--FDWCPDPPAVSNASVTVNGH--KAGSLASYTCENGHILSGSTSVTCTLG-- 514
P+C ++ C +P N T+ H +AG + C G L G ++TC G
Sbjct: 689 DRVPKCALKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHP 748
Query: 515 GAWSGVPPSCKYVNCGTPT 533
W+ PP CK P+
Sbjct: 749 SQWTSQPPLCKVTQTTDPS 767
Score = 81.4 bits (192), Expect = 2e-14
Identities = 49/168 (29%), Positives = 80/168 (47%), Gaps = 11/168 (6%)
Query: 806 GATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEI-TCPDPSAQIKAGSGLLVVTST 864
G YQC+ +EL G CQ + +WS PP C++I TC DP +I G +
Sbjct: 595 GTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKIMTCADPG-EIANGHRT-ASDAG 652
Query: 865 LSIGGEAHYQCERGYNLKGHQTRTCISKG----QWNGTVPVC-IPID-CRSPGNIENGKI 918
+G Y+C GY+L+G TC S+ +W+ VP C + + C +PG ENG
Sbjct: 653 FPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPKCALKYEPCLNPGVPENGYQ 712
Query: 919 VISNGSTLFGSSVEYYCLSQYQRVGPFLRKCL--DDGRWSGEEPSCEL 964
+ G S+ ++C ++ +G C+ +W+ + P C++
Sbjct: 713 TLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPLCKV 760
Score = 65.3 bits (152), Expect = 1e-09
Identities = 38/106 (35%), Positives = 45/106 (42%), Gaps = 5/106 (4%)
Query: 873 YQCERGYNLKGHQTRTCISKGQWNGTVPVCIPI-DCRSPGNIENGKIVISNGSTLFGSSV 931
YQCE GY L G TC W+ P C I C PG I NG S+ GS V
Sbjct: 600 YQCEPGYELLGSDILTCQWDLSWSAAPPACQKIMTCADPGEIANGHRTASDAGFPVGSHV 659
Query: 932 EYYCLSQYQRVGPFLRKCL--DDG--RWSGEEPSCELATNEAVDSG 973
+Y CL Y G + C D G +WS P C L ++ G
Sbjct: 660 QYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPKCALKYEPCLNPG 705
Score = 49.6 bits (113), Expect = 6e-05
Identities = 23/65 (35%), Positives = 35/65 (53%), Gaps = 3/65 (4%)
Query: 585 LTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQD--GEWSGDSPTCE 642
L SC P P+ G + D + T FHC++G++L GE L+C W+G++P+C
Sbjct: 217 LLSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSC- 275
Query: 643 YIDCG 647
CG
Sbjct: 276 MASCG 280
Score = 45.2 bits (102), Expect = 0.001
Identities = 27/89 (30%), Positives = 43/89 (48%), Gaps = 5/89 (5%)
Query: 471 CPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLG--GAWSGVPPSCKYVN 528
C PP ++ V+V G A++ C++G+ L G ++ C G +W+G PSC +
Sbjct: 220 CGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSC-MAS 278
Query: 529 CGTPTIHKGSFVLINGTTTYGSIA-QFTC 556
CG TIH + I G++ TC
Sbjct: 279 CG-GTIHNATLGRIVSPEPGGAVGPNLTC 306
Score = 41.9 bits (94), Expect = 0.012
Identities = 21/62 (33%), Positives = 32/62 (51%), Gaps = 2/62 (3%)
Query: 860 VVTSTLSIGGEAHYQCERGYNLKGHQTRTCI--SKGQWNGTVPVCIPIDCRSPGNIENGK 917
V + L GG A + C+ GY L+G +T C+ ++ WNG P C+ + N G+
Sbjct: 231 VSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCMASCGGTIHNATLGR 290
Query: 918 IV 919
IV
Sbjct: 291 IV 292
Score = 41.1 bits (92), Expect = 0.021
Identities = 22/89 (24%), Positives = 35/89 (39%), Gaps = 4/89 (4%)
Query: 8 PPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTNVAFRKP 67
PP + +++ GT+ Y+C+ GYEL G+ C W+ PP C + P
Sbjct: 579 PPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKIMTCADP 638
Query: 68 ANQSTTVRGGAAANGNDGEKTTEHDRKRC 96
+ G + G H + RC
Sbjct: 639 GE----IANGHRTASDAGFPVGSHVQYRC 663
Score = 36.3 bits (80), Expect = 0.60
Identities = 31/116 (26%), Positives = 46/116 (39%), Gaps = 7/116 (6%)
Query: 354 GSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGG 413
GSP L +L N +G V + P +LL +S + G + ++CG
Sbjct: 166 GSPG--LAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFR-IHYQAYLLSCGF 222
Query: 414 LTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTC--GDEGIWDGEAPRCL 467
GDV++ D G A + C + L G C G W+GE P C+
Sbjct: 223 PPRPAHGDVSVTDLHP--GGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCM 276
Score = 36.3 bits (80), Expect = 0.60
Identities = 18/64 (28%), Positives = 29/64 (45%), Gaps = 3/64 (4%)
Query: 352 TCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKD--GFWSGAPPSCKYV 409
+CG P + + + D G + C G+ L G+++ C W+G PSC
Sbjct: 219 SCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSC-MA 277
Query: 410 NCGG 413
+CGG
Sbjct: 278 SCGG 281
Score = 35.5 bits (78), Expect = 1.0
Identities = 20/59 (33%), Positives = 26/59 (44%), Gaps = 5/59 (8%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECT--LRGDWTLEPPFC 58
CG P P + VS+ + + G A + CD GY+L G C R W E P C
Sbjct: 220 CGFPPRPAHGDVSVTD---LHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSC 275
Score = 34.7 bits (76), Expect = 1.8
Identities = 21/61 (34%), Positives = 31/61 (50%), Gaps = 6/61 (9%)
Query: 783 VDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGT---WSLEPPI 839
+ CG P R +G V++ G TA + CD ++L+G +C NGT W+ E P
Sbjct: 218 LSCGFPPRPAHGDVSVTD--LHPGGTATFHCDSGYQLQGEETLICL-NGTRPSWNGETPS 274
Query: 840 C 840
C
Sbjct: 275 C 275
Score = 34.7 bits (76), Expect = 1.8
Identities = 19/59 (32%), Positives = 29/59 (49%), Gaps = 8/59 (13%)
Query: 746 GALVKYRCEKGYKVIGESLSTCEDNGQ--WSGTTPTCQYVDCGNPGRIEN---GKVTLP 799
G + C+ GY++ GE C + + W+G TP+C CG G I N G++ P
Sbjct: 239 GGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCM-ASCG--GTIHNATLGRIVSP 294
Score = 33.1 bits (72), Expect = 5.6
Identities = 16/42 (38%), Positives = 22/42 (52%), Gaps = 3/42 (7%)
Query: 549 GSIAQFTCEPDYWLNGAEELVCNRDGK--WSYDIPSCELTSC 588
G A F C+ Y L G E L+C + W+ + PSC + SC
Sbjct: 239 GGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSC-MASC 279
Score = 32.7 bits (71), Expect = 7.4
Identities = 19/72 (26%), Positives = 33/72 (45%), Gaps = 4/72 (5%)
Query: 905 IDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGR--WSGEEPSC 962
+ C P +G + +++ G + ++C S YQ G CL+ R W+GE PSC
Sbjct: 218 LSCGFPPRPAHGDVSVTDLHP--GGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSC 275
Query: 963 ELATNEAVDSGT 974
+ + + T
Sbjct: 276 MASCGGTIHNAT 287
>EF076058-1|ABK81638.1| 355|Homo sapiens CD46 protein.
Length = 355
Score = 101 bits (243), Expect = 1e-20
Identities = 64/257 (24%), Positives = 111/257 (43%), Gaps = 19/257 (7%)
Query: 369 YDVGSRIVYKCPEGHMLLGDKSRH--CKKDGFWSG-APPSCKYVNCGGLTPIEDGDVALI 425
Y++G R+ YKC +G+ + + H C ++ W + +C C + +G
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA 113
Query: 426 DNRTTHGARALYSCRENFTLVGNPERTC---GDEGIWDGEAPRCLFDWCPDPPAVSNASV 482
+ G + + C E + L+G C G IW G+ P C C PP + N
Sbjct: 114 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKH 173
Query: 483 T---VNGHKAGSLASYTCE-----NGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTI 534
T V + +Y+C+ + L G +++ C WS P CK V C P +
Sbjct: 174 TFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVV 233
Query: 535 HKGSFVLINGTTTY-GSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEV 593
G + G Y + F C+ ++L+G++ +VC+ + W +P C L P+PE
Sbjct: 234 ENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKC-LKGYPKPE- 291
Query: 594 PSGGYMEAFDYYVHSTI 610
G +++ D +V + I
Sbjct: 292 --EGILDSLDVWVIAVI 306
Score = 90.6 bits (215), Expect = 3e-17
Identities = 53/171 (30%), Positives = 75/171 (43%), Gaps = 11/171 (6%)
Query: 742 TYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTCQYVDCGNPGRIENGKVTL 798
TY G + + C +GY +IGE + CE G WSG P C+ V C P +I+NGK T
Sbjct: 116 TYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTF 175
Query: 799 PSNATF-YGATAFYQCD-----ENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQI 852
F Y Y CD + + L G C +N WS P CK + C P +
Sbjct: 176 SEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPV--V 233
Query: 853 KAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCI 903
+ G + ++C++G+ L G T C S W+ VP C+
Sbjct: 234 ENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCL 284
Score = 84.2 bits (199), Expect = 2e-15
Identities = 60/229 (26%), Positives = 91/229 (39%), Gaps = 21/229 (9%)
Query: 432 GARALYSCRENFTLVGN--PERTCGDEGIW-DGEAPRCLFDWCP---DPPAVSNASVTVN 485
G R Y C++ + + C W C + CP DP ++ +V N
Sbjct: 57 GERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDP--LNGQAVPAN 114
Query: 486 G-HKAGSLASYTCENGHILSGSTSVTCTLGGA---WSGVPPSCKYVNCGTPT-IHKGSFV 540
G ++ G + C G+ L G + C L G+ WSG PP C+ V C P I G
Sbjct: 115 GTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHT 174
Query: 541 LINGTT-TYGSIAQFTCEP-----DYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVP 594
Y ++C+P + L G + C + WS P C++ C P V
Sbjct: 175 FSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVE 234
Query: 595 SGGYMEAFD--YYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTC 641
+G + F +Y +T+ F C+ G L G +VC + W P C
Sbjct: 235 NGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 81.0 bits (191), Expect = 2e-14
Identities = 62/233 (26%), Positives = 96/233 (41%), Gaps = 16/233 (6%)
Query: 743 YRIGALVKYRCEKGYKVIG--ESLSTCEDNGQWSGTT-PTCQYVDCGNPGRIENGKVTLP 799
Y IG V Y+C+KGY I + + C+ N W + C C NG+ +P
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQ-AVP 112
Query: 800 SNATF-YGATAFYQCDENWELEGVIRRMCQENGT---WSLEPPICKEITCPDPSAQIKAG 855
+N T+ +G + C+E + L G C+ G+ WS +PPIC+++ C P +IK G
Sbjct: 113 ANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLC-TPPPKIKNG 171
Query: 856 SGLLVVTSTLSIGGEAHYQCERG-----YNLKGHQTRTCISKGQWNGTVPVCIPIDCRSP 910
Y C+ ++L G T C W+ P C + CR P
Sbjct: 172 KHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFP 231
Query: 911 GNIENGKIVISNGSTL-FGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
+ENGK + G + ++V + C + G C + W P C
Sbjct: 232 -VVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 77.8 bits (183), Expect = 2e-13
Identities = 65/256 (25%), Positives = 97/256 (37%), Gaps = 28/256 (10%)
Query: 469 DWCPDPPAVSNASVTVNG---HKAGSLASYTCENGH--ILSGSTSVTCTLGGAWSGVPP- 522
D C +PP + ++ G Y C+ G+ I +T C W V
Sbjct: 33 DACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDD 92
Query: 523 SCKYVNCGTPTIH---KGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGK---W 576
+C C P I G V NGT +G F C Y+L G E L C G W
Sbjct: 93 ACYRETC--PYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIW 150
Query: 577 SYDIPSCELTSC-PEPEVPSGGY----MEAFDYYVHSTINFHCEAG-----HKLIGEPNL 626
S P CE C P P++ +G + +E F+Y + + C+ LIGE +
Sbjct: 151 SGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYL--DAVTYSCDPAPGPDPFSLIGESTI 208
Query: 627 VCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTT-HLGSVIQYSCTTNYRLVGPVR 685
C + WS +P C+ + C + P + G G + + + + C + L G
Sbjct: 209 YCGDNSVWSRAAPECKVVKC-RFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDT 267
Query: 686 RTCTEEFQWSDSSPRC 701
C W P+C
Sbjct: 268 IVCDSNSTWDPPVPKC 283
Score = 76.2 bits (179), Expect = 6e-13
Identities = 66/252 (26%), Positives = 100/252 (39%), Gaps = 45/252 (17%)
Query: 549 GSIAQFTCEPDYWLNG--AEELVCNRDGKW-SYDIPSCELTSCP---EP----EVPSGGY 598
G + C+ Y+ A +C+R+ W +C +CP +P VP+ G
Sbjct: 57 GERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGT 116
Query: 599 MEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGE---WSGDSPTCEYIDCGKLPTLPYG 655
E F Y +H F C G+ LIGE L C+ G WSG P CE + C P + G
Sbjct: 117 YE-FGYQMH----FICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNG 171
Query: 656 --TMELLNGTTHLGSVIQYSCTTN-----YRLVGPVRRTCTEEFQWSDSSPRCEEIRCSD 708
T + +L +V YSC + L+G C + WS ++P C+ ++C
Sbjct: 172 KHTFSEVEVFEYLDAVT-YSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRF 230
Query: 709 PIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCE 768
P+V +S G + A V + C+KG+ + G C+
Sbjct: 231 PVVENGKQIS-------------------GFGKKFYYKATVMFECDKGFYLDGSDTIVCD 271
Query: 769 DNGQWSGTTPTC 780
N W P C
Sbjct: 272 SNSTWDPPVPKC 283
Score = 60.9 bits (141), Expect = 2e-08
Identities = 40/149 (26%), Positives = 59/149 (39%), Gaps = 12/149 (8%)
Query: 826 MCQENGTW-SLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGH 884
+C N TW + C TCP + + + T G + H+ C GY L G
Sbjct: 79 ICDRNHTWLPVSDDACYRETCPYIRDPLNGQA--VPANGTYEFGYQMHFICNEGYYLIGE 136
Query: 885 QTRTCISKGQ---WNGTVPVCIPIDCRSPGNIENGKIVISNGSTL-FGSSVEYYC----- 935
+ C KG W+G P+C + C P I+NGK S + +V Y C
Sbjct: 137 EILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPG 196
Query: 936 LSQYQRVGPFLRKCLDDGRWSGEEPSCEL 964
+ +G C D+ WS P C++
Sbjct: 197 PDPFSLIGESTIYCGDNSVWSRAAPECKV 225
>EF076057-1|ABK81637.1| 355|Homo sapiens CD46 protein.
Length = 355
Score = 101 bits (243), Expect = 1e-20
Identities = 64/257 (24%), Positives = 111/257 (43%), Gaps = 19/257 (7%)
Query: 369 YDVGSRIVYKCPEGHMLLGDKSRH--CKKDGFWSG-APPSCKYVNCGGLTPIEDGDVALI 425
Y++G R+ YKC +G+ + + H C ++ W + +C C + +G
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA 113
Query: 426 DNRTTHGARALYSCRENFTLVGNPERTC---GDEGIWDGEAPRCLFDWCPDPPAVSNASV 482
+ G + + C E + L+G C G IW G+ P C C PP + N
Sbjct: 114 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKH 173
Query: 483 T---VNGHKAGSLASYTCE-----NGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTI 534
T V + +Y+C+ + L G +++ C WS P CK V C P +
Sbjct: 174 TFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVV 233
Query: 535 HKGSFVLINGTTTY-GSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEV 593
G + G Y + F C+ ++L+G++ +VC+ + W +P C L P+PE
Sbjct: 234 ENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKC-LKGYPKPE- 291
Query: 594 PSGGYMEAFDYYVHSTI 610
G +++ D +V + I
Sbjct: 292 --EGILDSLDVWVIAVI 306
Score = 90.6 bits (215), Expect = 3e-17
Identities = 53/171 (30%), Positives = 75/171 (43%), Gaps = 11/171 (6%)
Query: 742 TYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTCQYVDCGNPGRIENGKVTL 798
TY G + + C +GY +IGE + CE G WSG P C+ V C P +I+NGK T
Sbjct: 116 TYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTF 175
Query: 799 PSNATF-YGATAFYQCD-----ENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQI 852
F Y Y CD + + L G C +N WS P CK + C P +
Sbjct: 176 SEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPV--V 233
Query: 853 KAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCI 903
+ G + ++C++G+ L G T C S W+ VP C+
Sbjct: 234 ENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCL 284
Score = 84.2 bits (199), Expect = 2e-15
Identities = 60/229 (26%), Positives = 91/229 (39%), Gaps = 21/229 (9%)
Query: 432 GARALYSCRENFTLVGN--PERTCGDEGIW-DGEAPRCLFDWCP---DPPAVSNASVTVN 485
G R Y C++ + + C W C + CP DP ++ +V N
Sbjct: 57 GERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDP--LNGQAVPAN 114
Query: 486 G-HKAGSLASYTCENGHILSGSTSVTCTLGGA---WSGVPPSCKYVNCGTPT-IHKGSFV 540
G ++ G + C G+ L G + C L G+ WSG PP C+ V C P I G
Sbjct: 115 GTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHT 174
Query: 541 LINGTT-TYGSIAQFTCEP-----DYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVP 594
Y ++C+P + L G + C + WS P C++ C P V
Sbjct: 175 FSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVE 234
Query: 595 SGGYMEAFD--YYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTC 641
+G + F +Y +T+ F C+ G L G +VC + W P C
Sbjct: 235 NGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 81.0 bits (191), Expect = 2e-14
Identities = 62/233 (26%), Positives = 96/233 (41%), Gaps = 16/233 (6%)
Query: 743 YRIGALVKYRCEKGYKVIG--ESLSTCEDNGQWSGTT-PTCQYVDCGNPGRIENGKVTLP 799
Y IG V Y+C+KGY I + + C+ N W + C C NG+ +P
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQ-AVP 112
Query: 800 SNATF-YGATAFYQCDENWELEGVIRRMCQENGT---WSLEPPICKEITCPDPSAQIKAG 855
+N T+ +G + C+E + L G C+ G+ WS +PPIC+++ C P +IK G
Sbjct: 113 ANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLC-TPPPKIKNG 171
Query: 856 SGLLVVTSTLSIGGEAHYQCERG-----YNLKGHQTRTCISKGQWNGTVPVCIPIDCRSP 910
Y C+ ++L G T C W+ P C + CR P
Sbjct: 172 KHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFP 231
Query: 911 GNIENGKIVISNGSTL-FGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
+ENGK + G + ++V + C + G C + W P C
Sbjct: 232 -VVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 77.8 bits (183), Expect = 2e-13
Identities = 65/256 (25%), Positives = 97/256 (37%), Gaps = 28/256 (10%)
Query: 469 DWCPDPPAVSNASVTVNG---HKAGSLASYTCENGH--ILSGSTSVTCTLGGAWSGVPP- 522
D C +PP + ++ G Y C+ G+ I +T C W V
Sbjct: 33 DACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDD 92
Query: 523 SCKYVNCGTPTIH---KGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGK---W 576
+C C P I G V NGT +G F C Y+L G E L C G W
Sbjct: 93 ACYRETC--PYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIW 150
Query: 577 SYDIPSCELTSC-PEPEVPSGGY----MEAFDYYVHSTINFHCEAG-----HKLIGEPNL 626
S P CE C P P++ +G + +E F+Y + + C+ LIGE +
Sbjct: 151 SGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYL--DAVTYSCDPAPGPDPFSLIGESTI 208
Query: 627 VCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTT-HLGSVIQYSCTTNYRLVGPVR 685
C + WS +P C+ + C + P + G G + + + + C + L G
Sbjct: 209 YCGDNSVWSRAAPECKVVKC-RFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDT 267
Query: 686 RTCTEEFQWSDSSPRC 701
C W P+C
Sbjct: 268 IVCDSNSTWDPPVPKC 283
Score = 76.2 bits (179), Expect = 6e-13
Identities = 66/252 (26%), Positives = 100/252 (39%), Gaps = 45/252 (17%)
Query: 549 GSIAQFTCEPDYWLNG--AEELVCNRDGKW-SYDIPSCELTSCP---EP----EVPSGGY 598
G + C+ Y+ A +C+R+ W +C +CP +P VP+ G
Sbjct: 57 GERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGT 116
Query: 599 MEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGE---WSGDSPTCEYIDCGKLPTLPYG 655
E F Y +H F C G+ LIGE L C+ G WSG P CE + C P + G
Sbjct: 117 YE-FGYQMH----FICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNG 171
Query: 656 --TMELLNGTTHLGSVIQYSCTTN-----YRLVGPVRRTCTEEFQWSDSSPRCEEIRCSD 708
T + +L +V YSC + L+G C + WS ++P C+ ++C
Sbjct: 172 KHTFSEVEVFEYLDAVT-YSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRF 230
Query: 709 PIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCE 768
P+V +S G + A V + C+KG+ + G C+
Sbjct: 231 PVVENGKQIS-------------------GFGKKFYYKATVMFECDKGFYLDGSDTIVCD 271
Query: 769 DNGQWSGTTPTC 780
N W P C
Sbjct: 272 SNSTWDPPVPKC 283
Score = 60.9 bits (141), Expect = 2e-08
Identities = 40/149 (26%), Positives = 59/149 (39%), Gaps = 12/149 (8%)
Query: 826 MCQENGTW-SLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGH 884
+C N TW + C TCP + + + T G + H+ C GY L G
Sbjct: 79 ICDRNHTWLPVSDDACYRETCPYIRDPLNGQA--VPANGTYEFGYQMHFICNEGYYLIGE 136
Query: 885 QTRTCISKGQ---WNGTVPVCIPIDCRSPGNIENGKIVISNGSTL-FGSSVEYYC----- 935
+ C KG W+G P+C + C P I+NGK S + +V Y C
Sbjct: 137 EILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPG 196
Query: 936 LSQYQRVGPFLRKCLDDGRWSGEEPSCEL 964
+ +G C D+ WS P C++
Sbjct: 197 PDPFSLIGESTIYCGDNSVWSRAAPECKV 225
>M29964-1|AAB59520.1| 252|Homo sapiens C4BPB protein.
Length = 252
Score = 101 bits (241), Expect = 2e-20
Identities = 51/174 (29%), Positives = 74/174 (42%), Gaps = 2/174 (1%)
Query: 471 CPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCG 530
CP+ P V N+ + L +Y C G+ L G ++ C W C+ +C
Sbjct: 23 CPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCP 82
Query: 531 TPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPE 590
P + G F +G F C Y L G+ C D W+ P C+ C
Sbjct: 83 DPVLVNGEF-SSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDP 141
Query: 591 PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYI 644
P P GY E ++ + STI+++CE + L+G C DGEWS P C+ I
Sbjct: 142 PGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQC-VDGEWSSALPVCKLI 194
Score = 85.0 bits (201), Expect = 1e-15
Identities = 49/168 (29%), Positives = 74/168 (44%), Gaps = 3/168 (1%)
Query: 551 IAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFDYYVHSTI 610
+ + C Y L G + L CN +W C L CP+P + +G + + V I
Sbjct: 44 LGTYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKI 103
Query: 611 NFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVI 670
F C + L G C +D W+ P C+ DC +G E N T LGS I
Sbjct: 104 TFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFT--LGSTI 161
Query: 671 QYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVS 718
Y C Y LVG + C + +WS + P C+ I+ + EK++++
Sbjct: 162 SYYCEDRYYLVGVQEQQCVDG-EWSSALPVCKLIQEAPKPECEKALLA 208
Score = 84.2 bits (199), Expect = 2e-15
Identities = 50/184 (27%), Positives = 81/184 (44%), Gaps = 7/184 (3%)
Query: 719 VTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTP 778
V+ +D H L ++ V L Y C KGY ++G+ C + +W TT
Sbjct: 15 VSASDAEHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTT 74
Query: 779 TCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPP 838
C+ C +P + NG+ + S + C++++ L+G R C E+ TW+ P
Sbjct: 75 ECRLGHCPDPVLV-NGEFS-SSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFP 132
Query: 839 ICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGT 898
ICK C P + + ++G Y CE Y L G Q + C+ G+W+
Sbjct: 133 ICKSRDCDPPGNPVHG----YFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVD-GEWSSA 187
Query: 899 VPVC 902
+PVC
Sbjct: 188 LPVC 191
Score = 81.0 bits (191), Expect = 2e-14
Identities = 49/159 (30%), Positives = 67/159 (42%), Gaps = 7/159 (4%)
Query: 437 YSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGSLASYT 496
Y C + + LVG C WD C CPDP V+ + ++
Sbjct: 47 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFM 106
Query: 497 CENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTP--TIHKGSFVLINGTTTYGSIAQF 554
C + +IL GS C W+ P CK +C P +H G F T GS +
Sbjct: 107 CNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVH-GYFE--GNNFTLGSTISY 163
Query: 555 TCEPDYWLNGAEELVCNRDGKWSYDIPSCEL-TSCPEPE 592
CE Y+L G +E C DG+WS +P C+L P+PE
Sbjct: 164 YCEDRYYLVGVQEQQC-VDGEWSSALPVCKLIQEAPKPE 201
Score = 78.2 bits (184), Expect = 1e-13
Identities = 46/154 (29%), Positives = 67/154 (43%), Gaps = 7/154 (4%)
Query: 811 YQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGE 870
Y C + + L G C + W C+ CPDP +G + +++ +
Sbjct: 47 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLV----NGEFSSSGPVNVSDK 102
Query: 871 AHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSS 930
+ C Y LKG C+ W P+C DC PGN +G N TL GS+
Sbjct: 103 ITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFE-GNNFTL-GST 160
Query: 931 VEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCEL 964
+ YYC +Y VG ++C+ DG WS P C+L
Sbjct: 161 ISYYCEDRYYLVGVQEQQCV-DGEWSSALPVCKL 193
Score = 71.7 bits (168), Expect = 1e-11
Identities = 50/207 (24%), Positives = 79/207 (38%), Gaps = 24/207 (11%)
Query: 577 SYDIPSCELTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSG 636
++ + + + CPE A + + C G+ L+G+ L C EW
Sbjct: 12 AWRVSASDAEHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKEWDN 71
Query: 637 DSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSD 696
+ C C P L G +G ++ I + C +Y L G R C E+ W+
Sbjct: 72 TTTECRLGHCPD-PVLVNGEFSS-SGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAP 129
Query: 697 SSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKG 756
P C+ C P GN HG+ GN + +G+ + Y CE
Sbjct: 130 PFPICKSRDCDPP-----------GNP-VHGYF---------EGNNFTLGSTISYYCEDR 168
Query: 757 YKVIGESLSTCEDNGQWSGTTPTCQYV 783
Y ++G C D G+WS P C+ +
Sbjct: 169 YYLVGVQEQQCVD-GEWSSALPVCKLI 194
Score = 59.7 bits (138), Expect = 6e-08
Identities = 36/151 (23%), Positives = 56/151 (37%), Gaps = 3/151 (1%)
Query: 377 YKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRTTHGARAL 436
Y C +G+ L+G K+ C W C+ +C P+ +
Sbjct: 47 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCP--DPVLVNGEFSSSGPVNVSDKIT 104
Query: 437 YSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGSLASYT 496
+ C +++ L G+ C ++ W P C C P + N GS SY
Sbjct: 105 FMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYY 164
Query: 497 CENGHILSGSTSVTCTLGGAWSGVPPSCKYV 527
CE+ + L G C + G WS P CK +
Sbjct: 165 CEDRYYLVGVQEQQC-VDGEWSSALPVCKLI 194
Score = 49.2 bits (112), Expect = 8e-05
Identities = 31/106 (29%), Positives = 44/106 (41%), Gaps = 4/106 (3%)
Query: 370 DVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRT 429
+V +I + C + ++L G C +D W+ P CK +C P N
Sbjct: 98 NVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCD--PPGNPVHGYFEGNNF 155
Query: 430 THGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRC-LFDWCPDP 474
T G+ Y C + + LVG E+ C D G W P C L P P
Sbjct: 156 TLGSTISYYCEDRYYLVGVQEQQCVD-GEWSSALPVCKLIQEAPKP 200
Score = 43.6 bits (98), Expect = 0.004
Identities = 20/57 (35%), Positives = 31/57 (54%), Gaps = 1/57 (1%)
Query: 353 CGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYV 409
C P ++ GN++ +GS I Y C + + L+G + + C DG WS A P CK +
Sbjct: 139 CDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQC-VDGEWSSALPVCKLI 194
Score = 32.3 bits (70), Expect = 9.7
Identities = 12/39 (30%), Positives = 22/39 (56%), Gaps = 1/39 (2%)
Query: 20 NIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
N G+ Y C++ Y L G ++++C + G+W+ P C
Sbjct: 154 NFTLGSTISYYCEDRYYLVGVQEQQC-VDGEWSSALPVC 191
>L11245-1|AAA35616.1| 252|Homo sapiens C4b-binding protein
beta-chain protein.
Length = 252
Score = 101 bits (241), Expect = 2e-20
Identities = 51/174 (29%), Positives = 74/174 (42%), Gaps = 2/174 (1%)
Query: 471 CPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCG 530
CP+ P V N+ + L +Y C G+ L G ++ C W C+ +C
Sbjct: 23 CPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCP 82
Query: 531 TPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPE 590
P + G F +G F C Y L G+ C D W+ P C+ C
Sbjct: 83 DPVLVNGEF-SSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDP 141
Query: 591 PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYI 644
P P GY E ++ + STI+++CE + L+G C DGEWS P C+ I
Sbjct: 142 PGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQC-VDGEWSSALPVCKLI 194
Score = 85.0 bits (201), Expect = 1e-15
Identities = 49/168 (29%), Positives = 74/168 (44%), Gaps = 3/168 (1%)
Query: 551 IAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFDYYVHSTI 610
+ + C Y L G + L CN +W C L CP+P + +G + + V I
Sbjct: 44 LGTYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKI 103
Query: 611 NFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVI 670
F C + L G C +D W+ P C+ DC +G E N T LGS I
Sbjct: 104 TFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFT--LGSTI 161
Query: 671 QYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVS 718
Y C Y LVG + C + +WS + P C+ I+ + EK++++
Sbjct: 162 SYYCEDRYYLVGVQEQQCVDG-EWSSALPVCKLIQEAPKPECEKALLA 208
Score = 84.2 bits (199), Expect = 2e-15
Identities = 50/184 (27%), Positives = 81/184 (44%), Gaps = 7/184 (3%)
Query: 719 VTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTP 778
V+ +D H L ++ V L Y C KGY ++G+ C + +W TT
Sbjct: 15 VSASDAEHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTT 74
Query: 779 TCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPP 838
C+ C +P + NG+ + S + C++++ L+G R C E+ TW+ P
Sbjct: 75 ECRLGHCPDPVLV-NGEFS-SSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFP 132
Query: 839 ICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGT 898
ICK C P + + ++G Y CE Y L G Q + C+ G+W+
Sbjct: 133 ICKSRDCDPPGNPVHG----YFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVD-GEWSSA 187
Query: 899 VPVC 902
+PVC
Sbjct: 188 LPVC 191
Score = 81.0 bits (191), Expect = 2e-14
Identities = 49/159 (30%), Positives = 67/159 (42%), Gaps = 7/159 (4%)
Query: 437 YSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGSLASYT 496
Y C + + LVG C WD C CPDP V+ + ++
Sbjct: 47 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFM 106
Query: 497 CENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTP--TIHKGSFVLINGTTTYGSIAQF 554
C + +IL GS C W+ P CK +C P +H G F T GS +
Sbjct: 107 CNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVH-GYFE--GNNFTLGSTISY 163
Query: 555 TCEPDYWLNGAEELVCNRDGKWSYDIPSCEL-TSCPEPE 592
CE Y+L G +E C DG+WS +P C+L P+PE
Sbjct: 164 YCEDRYYLVGVQEQQC-VDGEWSSALPVCKLIQEAPKPE 201
Score = 78.2 bits (184), Expect = 1e-13
Identities = 46/154 (29%), Positives = 67/154 (43%), Gaps = 7/154 (4%)
Query: 811 YQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGE 870
Y C + + L G C + W C+ CPDP +G + +++ +
Sbjct: 47 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLV----NGEFSSSGPVNVSDK 102
Query: 871 AHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSS 930
+ C Y LKG C+ W P+C DC PGN +G N TL GS+
Sbjct: 103 ITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFE-GNNFTL-GST 160
Query: 931 VEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCEL 964
+ YYC +Y VG ++C+ DG WS P C+L
Sbjct: 161 ISYYCEDRYYLVGVQEQQCV-DGEWSSALPVCKL 193
Score = 71.7 bits (168), Expect = 1e-11
Identities = 50/207 (24%), Positives = 79/207 (38%), Gaps = 24/207 (11%)
Query: 577 SYDIPSCELTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSG 636
++ + + + CPE A + + C G+ L+G+ L C EW
Sbjct: 12 AWRVSASDAEHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKEWDN 71
Query: 637 DSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSD 696
+ C C P L G +G ++ I + C +Y L G R C E+ W+
Sbjct: 72 TTTECRLGHCPD-PVLVNGEFSS-SGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAP 129
Query: 697 SSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKG 756
P C+ C P GN HG+ GN + +G+ + Y CE
Sbjct: 130 PFPICKSRDCDPP-----------GNP-VHGYF---------EGNNFTLGSTISYYCEDR 168
Query: 757 YKVIGESLSTCEDNGQWSGTTPTCQYV 783
Y ++G C D G+WS P C+ +
Sbjct: 169 YYLVGVQEQQCVD-GEWSSALPVCKLI 194
Score = 59.7 bits (138), Expect = 6e-08
Identities = 36/151 (23%), Positives = 56/151 (37%), Gaps = 3/151 (1%)
Query: 377 YKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRTTHGARAL 436
Y C +G+ L+G K+ C W C+ +C P+ +
Sbjct: 47 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCP--DPVLVNGEFSSSGPVNVSDKIT 104
Query: 437 YSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGSLASYT 496
+ C +++ L G+ C ++ W P C C P + N GS SY
Sbjct: 105 FMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYY 164
Query: 497 CENGHILSGSTSVTCTLGGAWSGVPPSCKYV 527
CE+ + L G C + G WS P CK +
Sbjct: 165 CEDRYYLVGVQEQQC-VDGEWSSALPVCKLI 194
Score = 49.2 bits (112), Expect = 8e-05
Identities = 31/106 (29%), Positives = 44/106 (41%), Gaps = 4/106 (3%)
Query: 370 DVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRT 429
+V +I + C + ++L G C +D W+ P CK +C P N
Sbjct: 98 NVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCD--PPGNPVHGYFEGNNF 155
Query: 430 THGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRC-LFDWCPDP 474
T G+ Y C + + LVG E+ C D G W P C L P P
Sbjct: 156 TLGSTISYYCEDRYYLVGVQEQQCVD-GEWSSALPVCKLIQEAPKP 200
Score = 43.6 bits (98), Expect = 0.004
Identities = 20/57 (35%), Positives = 31/57 (54%), Gaps = 1/57 (1%)
Query: 353 CGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYV 409
C P ++ GN++ +GS I Y C + + L+G + + C DG WS A P CK +
Sbjct: 139 CDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQC-VDGEWSSALPVCKLI 194
Score = 32.3 bits (70), Expect = 9.7
Identities = 12/39 (30%), Positives = 22/39 (56%), Gaps = 1/39 (2%)
Query: 20 NIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
N G+ Y C++ Y L G ++++C + G+W+ P C
Sbjct: 154 NFTLGSTISYYCEDRYYLVGVQEQQC-VDGEWSSALPVC 191
>L11244-1|AAA35615.1| 252|Homo sapiens C4b-binding protein
beta-chain protein.
Length = 252
Score = 101 bits (241), Expect = 2e-20
Identities = 51/174 (29%), Positives = 74/174 (42%), Gaps = 2/174 (1%)
Query: 471 CPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCG 530
CP+ P V N+ + L +Y C G+ L G ++ C W C+ +C
Sbjct: 23 CPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCP 82
Query: 531 TPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPE 590
P + G F +G F C Y L G+ C D W+ P C+ C
Sbjct: 83 DPVLVNGEF-SSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDP 141
Query: 591 PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYI 644
P P GY E ++ + STI+++CE + L+G C DGEWS P C+ I
Sbjct: 142 PGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQC-VDGEWSSALPVCKLI 194
Score = 85.0 bits (201), Expect = 1e-15
Identities = 49/168 (29%), Positives = 74/168 (44%), Gaps = 3/168 (1%)
Query: 551 IAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFDYYVHSTI 610
+ + C Y L G + L CN +W C L CP+P + +G + + V I
Sbjct: 44 LGTYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKI 103
Query: 611 NFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVI 670
F C + L G C +D W+ P C+ DC +G E N T LGS I
Sbjct: 104 TFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFT--LGSTI 161
Query: 671 QYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVS 718
Y C Y LVG + C + +WS + P C+ I+ + EK++++
Sbjct: 162 SYYCEDRYYLVGVQEQQCVDG-EWSSALPVCKLIQEAPKPECEKALLA 208
Score = 84.2 bits (199), Expect = 2e-15
Identities = 50/184 (27%), Positives = 81/184 (44%), Gaps = 7/184 (3%)
Query: 719 VTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTP 778
V+ +D H L ++ V L Y C KGY ++G+ C + +W TT
Sbjct: 15 VSASDAEHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTT 74
Query: 779 TCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPP 838
C+ C +P + NG+ + S + C++++ L+G R C E+ TW+ P
Sbjct: 75 ECRLGHCPDPVLV-NGEFS-SSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFP 132
Query: 839 ICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGT 898
ICK C P + + ++G Y CE Y L G Q + C+ G+W+
Sbjct: 133 ICKSRDCDPPGNPVHG----YFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVD-GEWSSA 187
Query: 899 VPVC 902
+PVC
Sbjct: 188 LPVC 191
Score = 81.0 bits (191), Expect = 2e-14
Identities = 49/159 (30%), Positives = 67/159 (42%), Gaps = 7/159 (4%)
Query: 437 YSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGSLASYT 496
Y C + + LVG C WD C CPDP V+ + ++
Sbjct: 47 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFM 106
Query: 497 CENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTP--TIHKGSFVLINGTTTYGSIAQF 554
C + +IL GS C W+ P CK +C P +H G F T GS +
Sbjct: 107 CNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVH-GYFE--GNNFTLGSTISY 163
Query: 555 TCEPDYWLNGAEELVCNRDGKWSYDIPSCEL-TSCPEPE 592
CE Y+L G +E C DG+WS +P C+L P+PE
Sbjct: 164 YCEDRYYLVGVQEQQC-VDGEWSSALPVCKLIQEAPKPE 201
Score = 78.2 bits (184), Expect = 1e-13
Identities = 46/154 (29%), Positives = 67/154 (43%), Gaps = 7/154 (4%)
Query: 811 YQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGE 870
Y C + + L G C + W C+ CPDP +G + +++ +
Sbjct: 47 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLV----NGEFSSSGPVNVSDK 102
Query: 871 AHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSS 930
+ C Y LKG C+ W P+C DC PGN +G N TL GS+
Sbjct: 103 ITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFE-GNNFTL-GST 160
Query: 931 VEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCEL 964
+ YYC +Y VG ++C+ DG WS P C+L
Sbjct: 161 ISYYCEDRYYLVGVQEQQCV-DGEWSSALPVCKL 193
Score = 71.7 bits (168), Expect = 1e-11
Identities = 50/207 (24%), Positives = 79/207 (38%), Gaps = 24/207 (11%)
Query: 577 SYDIPSCELTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSG 636
++ + + + CPE A + + C G+ L+G+ L C EW
Sbjct: 12 AWRVSASDAEHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKEWDN 71
Query: 637 DSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSD 696
+ C C P L G +G ++ I + C +Y L G R C E+ W+
Sbjct: 72 TTTECRLGHCPD-PVLVNGEFSS-SGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAP 129
Query: 697 SSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKG 756
P C+ C P GN HG+ GN + +G+ + Y CE
Sbjct: 130 PFPICKSRDCDPP-----------GNP-VHGYF---------EGNNFTLGSTISYYCEDR 168
Query: 757 YKVIGESLSTCEDNGQWSGTTPTCQYV 783
Y ++G C D G+WS P C+ +
Sbjct: 169 YYLVGVQEQQCVD-GEWSSALPVCKLI 194
Score = 59.7 bits (138), Expect = 6e-08
Identities = 36/151 (23%), Positives = 56/151 (37%), Gaps = 3/151 (1%)
Query: 377 YKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRTTHGARAL 436
Y C +G+ L+G K+ C W C+ +C P+ +
Sbjct: 47 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCP--DPVLVNGEFSSSGPVNVSDKIT 104
Query: 437 YSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGSLASYT 496
+ C +++ L G+ C ++ W P C C P + N GS SY
Sbjct: 105 FMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYY 164
Query: 497 CENGHILSGSTSVTCTLGGAWSGVPPSCKYV 527
CE+ + L G C + G WS P CK +
Sbjct: 165 CEDRYYLVGVQEQQC-VDGEWSSALPVCKLI 194
Score = 49.2 bits (112), Expect = 8e-05
Identities = 31/106 (29%), Positives = 44/106 (41%), Gaps = 4/106 (3%)
Query: 370 DVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRT 429
+V +I + C + ++L G C +D W+ P CK +C P N
Sbjct: 98 NVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCD--PPGNPVHGYFEGNNF 155
Query: 430 THGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRC-LFDWCPDP 474
T G+ Y C + + LVG E+ C D G W P C L P P
Sbjct: 156 TLGSTISYYCEDRYYLVGVQEQQCVD-GEWSSALPVCKLIQEAPKP 200
Score = 43.6 bits (98), Expect = 0.004
Identities = 20/57 (35%), Positives = 31/57 (54%), Gaps = 1/57 (1%)
Query: 353 CGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYV 409
C P ++ GN++ +GS I Y C + + L+G + + C DG WS A P CK +
Sbjct: 139 CDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQC-VDGEWSSALPVCKLI 194
Score = 32.3 bits (70), Expect = 9.7
Identities = 12/39 (30%), Positives = 22/39 (56%), Gaps = 1/39 (2%)
Query: 20 NIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
N G+ Y C++ Y L G ++++C + G+W+ P C
Sbjct: 154 NFTLGSTISYYCEDRYYLVGVQEQQC-VDGEWSSALPVC 191
>BC005378-1|AAH05378.1| 251|Homo sapiens complement component 4
binding protein, beta protein.
Length = 251
Score = 101 bits (241), Expect = 2e-20
Identities = 51/174 (29%), Positives = 74/174 (42%), Gaps = 2/174 (1%)
Query: 471 CPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCG 530
CP+ P V N+ + L +Y C G+ L G ++ C W C+ +C
Sbjct: 22 CPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCP 81
Query: 531 TPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPE 590
P + G F +G F C Y L G+ C D W+ P C+ C
Sbjct: 82 DPVLVNGEF-SSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDP 140
Query: 591 PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYI 644
P P GY E ++ + STI+++CE + L+G C DGEWS P C+ I
Sbjct: 141 PGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQC-VDGEWSSALPVCKLI 193
Score = 85.0 bits (201), Expect = 1e-15
Identities = 49/168 (29%), Positives = 74/168 (44%), Gaps = 3/168 (1%)
Query: 551 IAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFDYYVHSTI 610
+ + C Y L G + L CN +W C L CP+P + +G + + V I
Sbjct: 43 LGTYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKI 102
Query: 611 NFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVI 670
F C + L G C +D W+ P C+ DC +G E N T LGS I
Sbjct: 103 TFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFT--LGSTI 160
Query: 671 QYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVS 718
Y C Y LVG + C + +WS + P C+ I+ + EK++++
Sbjct: 161 SYYCEDRYYLVGVQEQQCVDG-EWSSALPVCKLIQEAPKPECEKALLA 207
Score = 83.0 bits (196), Expect = 5e-15
Identities = 44/152 (28%), Positives = 71/152 (46%), Gaps = 7/152 (4%)
Query: 751 YRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAF 810
Y C KGY ++G+ C + +W TT C+ C +P + NG+ + S
Sbjct: 46 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLV-NGEFS-SSGPVNVSDKIT 103
Query: 811 YQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGE 870
+ C++++ L+G R C E+ TW+ PICK C P + + ++G
Sbjct: 104 FMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHG----YFEGNNFTLGST 159
Query: 871 AHYQCERGYNLKGHQTRTCISKGQWNGTVPVC 902
Y CE Y L G Q + C+ G+W+ +PVC
Sbjct: 160 ISYYCEDRYYLVGVQEQQCVD-GEWSSALPVC 190
Score = 81.0 bits (191), Expect = 2e-14
Identities = 49/159 (30%), Positives = 67/159 (42%), Gaps = 7/159 (4%)
Query: 437 YSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGSLASYT 496
Y C + + LVG C WD C CPDP V+ + ++
Sbjct: 46 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFM 105
Query: 497 CENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTP--TIHKGSFVLINGTTTYGSIAQF 554
C + +IL GS C W+ P CK +C P +H G F T GS +
Sbjct: 106 CNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVH-GYFE--GNNFTLGSTISY 162
Query: 555 TCEPDYWLNGAEELVCNRDGKWSYDIPSCEL-TSCPEPE 592
CE Y+L G +E C DG+WS +P C+L P+PE
Sbjct: 163 YCEDRYYLVGVQEQQC-VDGEWSSALPVCKLIQEAPKPE 200
Score = 78.2 bits (184), Expect = 1e-13
Identities = 46/154 (29%), Positives = 67/154 (43%), Gaps = 7/154 (4%)
Query: 811 YQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGE 870
Y C + + L G C + W C+ CPDP +G + +++ +
Sbjct: 46 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLV----NGEFSSSGPVNVSDK 101
Query: 871 AHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSS 930
+ C Y LKG C+ W P+C DC PGN +G N TL GS+
Sbjct: 102 ITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFE-GNNFTL-GST 159
Query: 931 VEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCEL 964
+ YYC +Y VG ++C+ DG WS P C+L
Sbjct: 160 ISYYCEDRYYLVGVQEQQCV-DGEWSSALPVCKL 192
Score = 68.9 bits (161), Expect = 9e-11
Identities = 49/181 (27%), Positives = 73/181 (40%), Gaps = 25/181 (13%)
Query: 672 YSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLI 731
Y C Y LVG C +W +++ C C DP++ V G S G +
Sbjct: 46 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVL-------VNGEFSSSGP--V 96
Query: 732 RTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRI 791
SD + + C Y + G + S C ++ W+ P C+ DC PG
Sbjct: 97 NVSDK------------ITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNP 144
Query: 792 ENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEI-TCPDPSA 850
+G N G+T Y C++ + L GV + C + G WS P+CK I P P
Sbjct: 145 VHG--YFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVD-GEWSSALPVCKLIQEAPKPEC 201
Query: 851 Q 851
+
Sbjct: 202 E 202
Score = 59.7 bits (138), Expect = 6e-08
Identities = 36/151 (23%), Positives = 56/151 (37%), Gaps = 3/151 (1%)
Query: 377 YKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRTTHGARAL 436
Y C +G+ L+G K+ C W C+ +C P+ +
Sbjct: 46 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCP--DPVLVNGEFSSSGPVNVSDKIT 103
Query: 437 YSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGSLASYT 496
+ C +++ L G+ C ++ W P C C P + N GS SY
Sbjct: 104 FMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYY 163
Query: 497 CENGHILSGSTSVTCTLGGAWSGVPPSCKYV 527
CE+ + L G C + G WS P CK +
Sbjct: 164 CEDRYYLVGVQEQQC-VDGEWSSALPVCKLI 193
Score = 49.2 bits (112), Expect = 8e-05
Identities = 31/106 (29%), Positives = 44/106 (41%), Gaps = 4/106 (3%)
Query: 370 DVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRT 429
+V +I + C + ++L G C +D W+ P CK +C P N
Sbjct: 97 NVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCD--PPGNPVHGYFEGNNF 154
Query: 430 THGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRC-LFDWCPDP 474
T G+ Y C + + LVG E+ C D G W P C L P P
Sbjct: 155 TLGSTISYYCEDRYYLVGVQEQQCVD-GEWSSALPVCKLIQEAPKP 199
Score = 43.6 bits (98), Expect = 0.004
Identities = 20/57 (35%), Positives = 31/57 (54%), Gaps = 1/57 (1%)
Query: 353 CGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYV 409
C P ++ GN++ +GS I Y C + + L+G + + C DG WS A P CK +
Sbjct: 138 CDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQC-VDGEWSSALPVCKLI 193
Score = 32.3 bits (70), Expect = 9.7
Identities = 12/39 (30%), Positives = 22/39 (56%), Gaps = 1/39 (2%)
Query: 20 NIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
N G+ Y C++ Y L G ++++C + G+W+ P C
Sbjct: 153 NFTLGSTISYYCEDRYYLVGVQEQQC-VDGEWSSALPVC 190
>AL445493-7|CAH70781.1| 251|Homo sapiens complement component 4
binding protein, beta protein.
Length = 251
Score = 101 bits (241), Expect = 2e-20
Identities = 51/174 (29%), Positives = 74/174 (42%), Gaps = 2/174 (1%)
Query: 471 CPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCG 530
CP+ P V N+ + L +Y C G+ L G ++ C W C+ +C
Sbjct: 22 CPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCP 81
Query: 531 TPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPE 590
P + G F +G F C Y L G+ C D W+ P C+ C
Sbjct: 82 DPVLVNGEF-SSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDP 140
Query: 591 PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYI 644
P P GY E ++ + STI+++CE + L+G C DGEWS P C+ I
Sbjct: 141 PGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQC-VDGEWSSALPVCKLI 193
Score = 85.0 bits (201), Expect = 1e-15
Identities = 49/168 (29%), Positives = 74/168 (44%), Gaps = 3/168 (1%)
Query: 551 IAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFDYYVHSTI 610
+ + C Y L G + L CN +W C L CP+P + +G + + V I
Sbjct: 43 LGTYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKI 102
Query: 611 NFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVI 670
F C + L G C +D W+ P C+ DC +G E N T LGS I
Sbjct: 103 TFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFT--LGSTI 160
Query: 671 QYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVS 718
Y C Y LVG + C + +WS + P C+ I+ + EK++++
Sbjct: 161 SYYCEDRYYLVGVQEQQCVDG-EWSSALPVCKLIQEAPKPECEKALLA 207
Score = 83.0 bits (196), Expect = 5e-15
Identities = 44/152 (28%), Positives = 71/152 (46%), Gaps = 7/152 (4%)
Query: 751 YRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAF 810
Y C KGY ++G+ C + +W TT C+ C +P + NG+ + S
Sbjct: 46 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLV-NGEFS-SSGPVNVSDKIT 103
Query: 811 YQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGE 870
+ C++++ L+G R C E+ TW+ PICK C P + + ++G
Sbjct: 104 FMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHG----YFEGNNFTLGST 159
Query: 871 AHYQCERGYNLKGHQTRTCISKGQWNGTVPVC 902
Y CE Y L G Q + C+ G+W+ +PVC
Sbjct: 160 ISYYCEDRYYLVGVQEQQCVD-GEWSSALPVC 190
Score = 81.0 bits (191), Expect = 2e-14
Identities = 49/159 (30%), Positives = 67/159 (42%), Gaps = 7/159 (4%)
Query: 437 YSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGSLASYT 496
Y C + + LVG C WD C CPDP V+ + ++
Sbjct: 46 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFM 105
Query: 497 CENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTP--TIHKGSFVLINGTTTYGSIAQF 554
C + +IL GS C W+ P CK +C P +H G F T GS +
Sbjct: 106 CNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVH-GYFE--GNNFTLGSTISY 162
Query: 555 TCEPDYWLNGAEELVCNRDGKWSYDIPSCEL-TSCPEPE 592
CE Y+L G +E C DG+WS +P C+L P+PE
Sbjct: 163 YCEDRYYLVGVQEQQC-VDGEWSSALPVCKLIQEAPKPE 200
Score = 78.2 bits (184), Expect = 1e-13
Identities = 46/154 (29%), Positives = 67/154 (43%), Gaps = 7/154 (4%)
Query: 811 YQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGE 870
Y C + + L G C + W C+ CPDP +G + +++ +
Sbjct: 46 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLV----NGEFSSSGPVNVSDK 101
Query: 871 AHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSS 930
+ C Y LKG C+ W P+C DC PGN +G N TL GS+
Sbjct: 102 ITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFE-GNNFTL-GST 159
Query: 931 VEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCEL 964
+ YYC +Y VG ++C+ DG WS P C+L
Sbjct: 160 ISYYCEDRYYLVGVQEQQCV-DGEWSSALPVCKL 192
Score = 68.9 bits (161), Expect = 9e-11
Identities = 49/181 (27%), Positives = 73/181 (40%), Gaps = 25/181 (13%)
Query: 672 YSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLI 731
Y C Y LVG C +W +++ C C DP++ V G S G +
Sbjct: 46 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVL-------VNGEFSSSGP--V 96
Query: 732 RTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRI 791
SD + + C Y + G + S C ++ W+ P C+ DC PG
Sbjct: 97 NVSDK------------ITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNP 144
Query: 792 ENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEI-TCPDPSA 850
+G N G+T Y C++ + L GV + C + G WS P+CK I P P
Sbjct: 145 VHG--YFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVD-GEWSSALPVCKLIQEAPKPEC 201
Query: 851 Q 851
+
Sbjct: 202 E 202
Score = 59.7 bits (138), Expect = 6e-08
Identities = 36/151 (23%), Positives = 56/151 (37%), Gaps = 3/151 (1%)
Query: 377 YKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRTTHGARAL 436
Y C +G+ L+G K+ C W C+ +C P+ +
Sbjct: 46 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCP--DPVLVNGEFSSSGPVNVSDKIT 103
Query: 437 YSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGSLASYT 496
+ C +++ L G+ C ++ W P C C P + N GS SY
Sbjct: 104 FMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYY 163
Query: 497 CENGHILSGSTSVTCTLGGAWSGVPPSCKYV 527
CE+ + L G C + G WS P CK +
Sbjct: 164 CEDRYYLVGVQEQQC-VDGEWSSALPVCKLI 193
Score = 49.2 bits (112), Expect = 8e-05
Identities = 31/106 (29%), Positives = 44/106 (41%), Gaps = 4/106 (3%)
Query: 370 DVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRT 429
+V +I + C + ++L G C +D W+ P CK +C P N
Sbjct: 97 NVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCD--PPGNPVHGYFEGNNF 154
Query: 430 THGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRC-LFDWCPDP 474
T G+ Y C + + LVG E+ C D G W P C L P P
Sbjct: 155 TLGSTISYYCEDRYYLVGVQEQQCVD-GEWSSALPVCKLIQEAPKP 199
Score = 43.6 bits (98), Expect = 0.004
Identities = 20/57 (35%), Positives = 31/57 (54%), Gaps = 1/57 (1%)
Query: 353 CGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYV 409
C P ++ GN++ +GS I Y C + + L+G + + C DG WS A P CK +
Sbjct: 138 CDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQC-VDGEWSSALPVCKLI 193
Score = 32.3 bits (70), Expect = 9.7
Identities = 12/39 (30%), Positives = 22/39 (56%), Gaps = 1/39 (2%)
Query: 20 NIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
N G+ Y C++ Y L G ++++C + G+W+ P C
Sbjct: 153 NFTLGSTISYYCEDRYYLVGVQEQQC-VDGEWSSALPVC 190
>AL445493-6|CAH70780.1| 252|Homo sapiens complement component 4
binding protein, beta protein.
Length = 252
Score = 101 bits (241), Expect = 2e-20
Identities = 51/174 (29%), Positives = 74/174 (42%), Gaps = 2/174 (1%)
Query: 471 CPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCG 530
CP+ P V N+ + L +Y C G+ L G ++ C W C+ +C
Sbjct: 23 CPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCP 82
Query: 531 TPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPE 590
P + G F +G F C Y L G+ C D W+ P C+ C
Sbjct: 83 DPVLVNGEF-SSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDP 141
Query: 591 PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYI 644
P P GY E ++ + STI+++CE + L+G C DGEWS P C+ I
Sbjct: 142 PGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQC-VDGEWSSALPVCKLI 194
Score = 85.0 bits (201), Expect = 1e-15
Identities = 49/168 (29%), Positives = 74/168 (44%), Gaps = 3/168 (1%)
Query: 551 IAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFDYYVHSTI 610
+ + C Y L G + L CN +W C L CP+P + +G + + V I
Sbjct: 44 LGTYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKI 103
Query: 611 NFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVI 670
F C + L G C +D W+ P C+ DC +G E N T LGS I
Sbjct: 104 TFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFT--LGSTI 161
Query: 671 QYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVS 718
Y C Y LVG + C + +WS + P C+ I+ + EK++++
Sbjct: 162 SYYCEDRYYLVGVQEQQCVDG-EWSSALPVCKLIQEAPKPECEKALLA 208
Score = 84.2 bits (199), Expect = 2e-15
Identities = 50/184 (27%), Positives = 81/184 (44%), Gaps = 7/184 (3%)
Query: 719 VTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTP 778
V+ +D H L ++ V L Y C KGY ++G+ C + +W TT
Sbjct: 15 VSASDAEHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTT 74
Query: 779 TCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPP 838
C+ C +P + NG+ + S + C++++ L+G R C E+ TW+ P
Sbjct: 75 ECRLGHCPDPVLV-NGEFS-SSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFP 132
Query: 839 ICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGT 898
ICK C P + + ++G Y CE Y L G Q + C+ G+W+
Sbjct: 133 ICKSRDCDPPGNPVHG----YFEGNNFTLGSTISYYCEDRYYLVGVQEQQCVD-GEWSSA 187
Query: 899 VPVC 902
+PVC
Sbjct: 188 LPVC 191
Score = 81.0 bits (191), Expect = 2e-14
Identities = 49/159 (30%), Positives = 67/159 (42%), Gaps = 7/159 (4%)
Query: 437 YSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGSLASYT 496
Y C + + LVG C WD C CPDP V+ + ++
Sbjct: 47 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFM 106
Query: 497 CENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTP--TIHKGSFVLINGTTTYGSIAQF 554
C + +IL GS C W+ P CK +C P +H G F T GS +
Sbjct: 107 CNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVH-GYFE--GNNFTLGSTISY 163
Query: 555 TCEPDYWLNGAEELVCNRDGKWSYDIPSCEL-TSCPEPE 592
CE Y+L G +E C DG+WS +P C+L P+PE
Sbjct: 164 YCEDRYYLVGVQEQQC-VDGEWSSALPVCKLIQEAPKPE 201
Score = 78.2 bits (184), Expect = 1e-13
Identities = 46/154 (29%), Positives = 67/154 (43%), Gaps = 7/154 (4%)
Query: 811 YQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGE 870
Y C + + L G C + W C+ CPDP +G + +++ +
Sbjct: 47 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLV----NGEFSSSGPVNVSDK 102
Query: 871 AHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSS 930
+ C Y LKG C+ W P+C DC PGN +G N TL GS+
Sbjct: 103 ITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFE-GNNFTL-GST 160
Query: 931 VEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCEL 964
+ YYC +Y VG ++C+ DG WS P C+L
Sbjct: 161 ISYYCEDRYYLVGVQEQQCV-DGEWSSALPVCKL 193
Score = 71.7 bits (168), Expect = 1e-11
Identities = 50/207 (24%), Positives = 79/207 (38%), Gaps = 24/207 (11%)
Query: 577 SYDIPSCELTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSG 636
++ + + + CPE A + + C G+ L+G+ L C EW
Sbjct: 12 AWRVSASDAEHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKEWDN 71
Query: 637 DSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSD 696
+ C C P L G +G ++ I + C +Y L G R C E+ W+
Sbjct: 72 TTTECRLGHCPD-PVLVNGEFSS-SGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAP 129
Query: 697 SSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKG 756
P C+ C P GN HG+ GN + +G+ + Y CE
Sbjct: 130 PFPICKSRDCDPP-----------GNP-VHGYF---------EGNNFTLGSTISYYCEDR 168
Query: 757 YKVIGESLSTCEDNGQWSGTTPTCQYV 783
Y ++G C D G+WS P C+ +
Sbjct: 169 YYLVGVQEQQCVD-GEWSSALPVCKLI 194
Score = 59.7 bits (138), Expect = 6e-08
Identities = 36/151 (23%), Positives = 56/151 (37%), Gaps = 3/151 (1%)
Query: 377 YKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRTTHGARAL 436
Y C +G+ L+G K+ C W C+ +C P+ +
Sbjct: 47 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCP--DPVLVNGEFSSSGPVNVSDKIT 104
Query: 437 YSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGSLASYT 496
+ C +++ L G+ C ++ W P C C P + N GS SY
Sbjct: 105 FMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYY 164
Query: 497 CENGHILSGSTSVTCTLGGAWSGVPPSCKYV 527
CE+ + L G C + G WS P CK +
Sbjct: 165 CEDRYYLVGVQEQQC-VDGEWSSALPVCKLI 194
Score = 49.2 bits (112), Expect = 8e-05
Identities = 31/106 (29%), Positives = 44/106 (41%), Gaps = 4/106 (3%)
Query: 370 DVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRT 429
+V +I + C + ++L G C +D W+ P CK +C P N
Sbjct: 98 NVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCD--PPGNPVHGYFEGNNF 155
Query: 430 THGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRC-LFDWCPDP 474
T G+ Y C + + LVG E+ C D G W P C L P P
Sbjct: 156 TLGSTISYYCEDRYYLVGVQEQQCVD-GEWSSALPVCKLIQEAPKP 200
Score = 43.6 bits (98), Expect = 0.004
Identities = 20/57 (35%), Positives = 31/57 (54%), Gaps = 1/57 (1%)
Query: 353 CGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYV 409
C P ++ GN++ +GS I Y C + + L+G + + C DG WS A P CK +
Sbjct: 139 CDPPGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQC-VDGEWSSALPVCKLI 194
Score = 32.3 bits (70), Expect = 9.7
Identities = 12/39 (30%), Positives = 22/39 (56%), Gaps = 1/39 (2%)
Query: 20 NIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
N G+ Y C++ Y L G ++++C + G+W+ P C
Sbjct: 154 NFTLGSTISYYCEDRYYLVGVQEQQC-VDGEWSSALPVC 191
>M15799-1|AAA52167.1| 376|Homo sapiens DAF protein.
Length = 376
Score = 98.3 bits (234), Expect = 1e-19
Identities = 66/228 (28%), Positives = 99/228 (43%), Gaps = 17/228 (7%)
Query: 748 LVKYRCEKGY-KVIGESLS-TCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFY 805
++ Y+CE+ + K+ GE S TC QWS C C P R+ + + P Y
Sbjct: 55 VITYKCEESFVKIPGEKDSVTCLKGMQWSDIEEFCNR-SCEVPTRLNSASLKQPYITQNY 113
Query: 806 ---GATAFYQCDENWELEGVI--RRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLV 860
G Y+C + E + + C +N WS CK+ +CP+P +I+ +G +
Sbjct: 114 FPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPG-EIR--NGQID 170
Query: 861 VTSTLSIGGEAHYQCERGYNLKGHQTRTCISKG---QWNGTVPVCIPIDCRSPGNIENGK 917
V + G + C GY L G + C+ G QW+ +P C I C +P I+NG
Sbjct: 171 VPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGI 230
Query: 918 IVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCL---DDGRWSGEEPSC 962
I + SV Y C + +G C D+G WSG P C
Sbjct: 231 IQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPEC 278
Score = 97.1 bits (231), Expect = 3e-19
Identities = 69/249 (27%), Positives = 107/249 (42%), Gaps = 19/249 (7%)
Query: 471 CPDPPAVSNASVTVNGHKA---GSLASYTCENGHI-LSGST-SVTCTLGGAWSGVPPSCK 525
C PP V NA + G + ++ +Y CE + + G SVTC G WS + C
Sbjct: 31 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVTCLKGMQWSDIEEFCN 90
Query: 526 YVNCGTPT-IHKGSFVLINGTTTY---GSIAQFTCEPDYWLNGA--EELVCNRDGKWSYD 579
+C PT ++ S T Y G++ ++ C P Y + +L C ++ KWS
Sbjct: 91 R-SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTA 149
Query: 580 IPSCELTSCPEP-EVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDG---EWS 635
+ C+ SCP P E+ +G +TI+F C G+KL G + C G +WS
Sbjct: 150 VEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWS 209
Query: 636 GDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCT---EEF 692
P C I C P + G ++ + Y+C + ++G CT +E
Sbjct: 210 DPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEG 269
Query: 693 QWSDSSPRC 701
+WS P C
Sbjct: 270 EWSGPPPEC 278
Score = 94.3 bits (224), Expect = 2e-18
Identities = 80/271 (29%), Positives = 112/271 (41%), Gaps = 35/271 (12%)
Query: 645 DCGKLPTLPYGTMELLNGTTHL--GSVIQYSCTTNY-RLVGPVRR-TCTEEFQWSDSSPR 700
DCG P +P L G T +VI Y C ++ ++ G TC + QWSD
Sbjct: 30 DCGLPPDVP-NAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVTCLKGMQWSDIEEF 88
Query: 701 CEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVI 760
C C P N S I N + +G +V+Y C GY+
Sbjct: 89 CNR-SCEVPTRL---------NSASLKQPYITQ-------NYFPVGTVVEYECRPGYRR- 130
Query: 761 GESLS---TCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENW 817
SLS TC N +WS C+ C NPG I NG++ +P F GAT + C+ +
Sbjct: 131 EPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILF-GATISFSCNTGY 189
Query: 818 ELEGVIRRMCQENGT---WSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQ 874
+L G C +G+ WS P C+EI CP P QI G + Y
Sbjct: 190 KLFGSTSSFCLISGSSVQWSDPLPECREIYCPAP-PQIDNGI-IQGERDHYGYRQSVTYA 247
Query: 875 CERGYNLKGHQTRTCI---SKGQWNGTVPVC 902
C +G+ + G + C +G+W+G P C
Sbjct: 248 CNKGFTMIGEHSIYCTVNNDEGEWSGPPPEC 278
Score = 86.2 bits (204), Expect = 6e-16
Identities = 66/248 (26%), Positives = 102/248 (41%), Gaps = 20/248 (8%)
Query: 413 GLTPIEDGDVALIDNRTTHGARAL--YSCRENFTLV-GNPER-TCGDEGIWDGEAPRCLF 468
GL P ++ RT+ + Y C E+F + G + TC W C
Sbjct: 32 GLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVTCLKGMQWSDIEEFCNR 91
Query: 469 DWCPDPPAVSNAS-----VTVNGHKAGSLASYTCENGHILSGSTS--VTCTLGGAWSGVP 521
C P +++AS +T N G++ Y C G+ S S +TC WS
Sbjct: 92 S-CEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAV 150
Query: 522 PSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDG---KWSY 578
CK +C P + + + G +G+ F+C Y L G+ C G +WS
Sbjct: 151 EFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSD 210
Query: 579 DIPSCELTSCP-EPEVPSGGYMEAFDYY-VHSTINFHCEAGHKLIGEPNLVC---QQDGE 633
+P C CP P++ +G D+Y ++ + C G +IGE ++ C +GE
Sbjct: 211 PLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGE 270
Query: 634 WSGDSPTC 641
WSG P C
Sbjct: 271 WSGPPPEC 278
Score = 83.4 bits (197), Expect = 4e-15
Identities = 71/271 (26%), Positives = 112/271 (41%), Gaps = 38/271 (14%)
Query: 528 NCGTPTIHKGSFVLINGTTTY--GSIAQFTCEPDYW-LNGAEELV-CNRDGKWSYDIPSC 583
+CG P + + G T++ ++ + CE + + G ++ V C + +WS DI
Sbjct: 30 DCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVTCLKGMQWS-DIEEF 88
Query: 584 ELTSCPEP-EVPSGGYMEAF---DYY-VHSTINFHCEAGHKLIGE--PNLVCQQDGEWSG 636
SC P + S + + +Y+ V + + + C G++ P L C Q+ +WS
Sbjct: 89 CNRSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWST 148
Query: 637 DSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCT---EEFQ 693
C+ C + G +++ G G+ I +SC T Y+L G C Q
Sbjct: 149 AVEFCKKKSCPNPGEIRNGQIDVPGGIL-FGATISFSCNTGYKLFGSTSSFCLISGSSVQ 207
Query: 694 WSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRC 753
WSD P C EI C P + I+ +R H Y V Y C
Sbjct: 208 WSDPLPECREIYCPAPPQIDNGIIQ---GERDH----------------YGYRQSVTYAC 248
Query: 754 EKGYKVIGESLSTC---EDNGQWSGTTPTCQ 781
KG+ +IGE C D G+WSG P C+
Sbjct: 249 NKGFTMIGEHSIYCTVNNDEGEWSGPPPECR 279
Score = 79.4 bits (187), Expect = 6e-14
Identities = 68/265 (25%), Positives = 108/265 (40%), Gaps = 26/265 (9%)
Query: 301 LVSKPSWGKDQPNNYNGEQNCVVLDGGR-------GWLWNDVGCNLDYLHWICQYLPPTC 353
L + S+ +D Y E++ V + G + G W+D+ ++ + C+ PT
Sbjct: 44 LEGRTSFPEDTVITYKCEESFVKIPGEKDSVTCLKGMQWSDIE---EFCNRSCEV--PTR 98
Query: 354 GSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRH--CKKDGFWSGAPPSCKYVNC 411
+ L I N + VG+ + Y+C G+ S C ++ WS A CK +C
Sbjct: 99 LNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSC 158
Query: 412 GGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTC---GDEGIWDGEAPRCLF 468
I +G + + GA +SC + L G+ C G W P C
Sbjct: 159 PNPGEIRNGQID-VPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECRE 217
Query: 469 DWCPDPPAVSNASVTVNGHKAGSLAS--YTCENGHILSGSTSVTCTLG---GAWSGVPPS 523
+CP PP + N + G S Y C G + G S+ CT+ G WSG PP
Sbjct: 218 IYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPE 277
Query: 524 CKYVNCGT---PTIHKGSFVLINGT 545
C+ + + PT+ K + V + T
Sbjct: 278 CRGKSLTSKVPPTVQKPTTVNVPTT 302
Score = 72.9 bits (171), Expect = 6e-12
Identities = 67/267 (25%), Positives = 112/267 (41%), Gaps = 38/267 (14%)
Query: 591 PEVPSGG-YMEAFDYYVHST-INFHCEAGH-KLIGEPNLV-CQQDGEWSGDSPTCEYIDC 646
P+VP+ +E + T I + CE K+ GE + V C + +WS C C
Sbjct: 35 PDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVTCLKGMQWSDIEEFCNR-SC 93
Query: 647 GKLPT-LPYGTME---LLNGTTHLGSVIQYSCTTNYRLVGPV--RRTCTEEFQWSDSSPR 700
++PT L +++ + +G+V++Y C YR + + TC + +WS +
Sbjct: 94 -EVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEF 152
Query: 701 CEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVI 760
C++ C +P + V G GA + + C GYK+
Sbjct: 153 CKKKSCPNPGEIRNGQIDVPGG--------------------ILFGATISFSCNTGYKLF 192
Query: 761 GESLSTCEDNG---QWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENW 817
G + S C +G QWS P C+ + C P +I+NG + + Y + Y C++ +
Sbjct: 193 GSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGF 252
Query: 818 ELEGVIRRMCQEN---GTWSLEPPICK 841
+ G C N G WS PP C+
Sbjct: 253 TMIGEHSIYCTVNNDEGEWSGPPPECR 279
Score = 72.1 bits (169), Expect = 1e-11
Identities = 51/188 (27%), Positives = 82/188 (43%), Gaps = 11/188 (5%)
Query: 784 DCGNPGRIENGKVTLPSNATFYGATAF-YQCDENW-ELEGVIRRM-CQENGTWSLEPPIC 840
DCG P + N + L +F T Y+C+E++ ++ G + C + WS C
Sbjct: 30 DCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVTCLKGMQWSDIEEFC 89
Query: 841 KEITCPDPSAQIKAGSGLLVVTST-LSIGGEAHYQCERGYNLKGHQTR--TCISKGQWNG 897
+C P+ A +T +G Y+C GY + + TC+ +W+
Sbjct: 90 NR-SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWST 148
Query: 898 TVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDG---R 954
V C C +PG I NG+I + G LFG+++ + C + Y+ G CL G +
Sbjct: 149 AVEFCKKKSCPNPGEIRNGQIDVP-GGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQ 207
Query: 955 WSGEEPSC 962
WS P C
Sbjct: 208 WSDPLPEC 215
Score = 34.3 bits (75), Expect = 2.4
Identities = 17/60 (28%), Positives = 28/60 (46%), Gaps = 5/60 (8%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRG---DWTLEPPFC 58
C +P N ++ +P I+ G + C+ GY+LFG+ C + G W+ P C
Sbjct: 158 CPNPGEIRNGQIDVPG--GILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPEC 215
Score = 32.3 bits (70), Expect = 9.7
Identities = 16/59 (27%), Positives = 29/59 (49%), Gaps = 2/59 (3%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGY-ELFGARQRECTLRG-DWTLEPPFC 58
CG P PNA+ ++ + T+ Y+C+E + ++ G + L+G W+ FC
Sbjct: 31 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVTCLKGMQWSDIEEFC 89
>X58100-1|CAA41113.1| 345|Homo sapiens Beta-2-glycoprotein I
apolipoprotein H protein.
Length = 345
Score = 97.9 bits (233), Expect = 2e-19
Identities = 62/228 (27%), Positives = 92/228 (40%), Gaps = 13/228 (5%)
Query: 432 GARALYSCRENFTLVGNPER-TCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAG 490
G YSC+ + G + C G+W +C CP + N +V +
Sbjct: 44 GEEITYSCKPGYVSRGGMRKFICPLTGLWPINTLKCTPRVCPFAGILENGAVRYTTFEYP 103
Query: 491 SLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTIHKGSFVLI-----NGT 545
+ S++C G L+G+ S CT G WS P C + C P+I + + +
Sbjct: 104 NTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAPIICPPPSIPTFATLRVYKPSAGNN 163
Query: 546 TTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGG---YMEAF 602
+ Y A F C P + + G + + C G W+ +P C CP P P G Y
Sbjct: 164 SLYRDTAVFECLPQHAMFGNDTITCTTHGNWT-KLPECREVKCPFPSRPDNGFVNYPAKP 222
Query: 603 DYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLP 650
Y F C G+ L G + C + G WS P+C+ C KLP
Sbjct: 223 TLYYKDKATFGCHDGYSLDGPEEIECTKLGNWSA-MPSCK-ASC-KLP 267
Score = 92.3 bits (219), Expect = 9e-18
Identities = 64/251 (25%), Positives = 100/251 (39%), Gaps = 16/251 (6%)
Query: 471 CPDPPAVSNASVTV--NGHKAGSLASYTCENGHILSGST-SVTCTLGGAWSGVPPSCKYV 527
CP P + ++V ++ G +Y+C+ G++ G C L G W C
Sbjct: 23 CPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYVSRGGMRKFICPLTGLWPINTLKCTPR 82
Query: 528 NCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTS 587
C I + V T Y + F+C ++LNGA+ C +GKWS ++P C
Sbjct: 83 VCPFAGILENGAVRYT-TFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAPII 141
Query: 588 CPEPEVPSGGYMEAF------DYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTC 641
CP P +P+ + + + T F C H + G + C G W+ P C
Sbjct: 142 CPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWT-KLPEC 200
Query: 642 EYIDCGKLPTLP-YGTMEL-LNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSP 699
+ C P+ P G + T + + C Y L GP CT+ WS + P
Sbjct: 201 REVKC-PFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSLDGPEEIECTKLGNWS-AMP 258
Query: 700 RCEEIRCSDPI 710
C + C P+
Sbjct: 259 SC-KASCKLPV 268
Score = 89.8 bits (213), Expect = 5e-17
Identities = 68/237 (28%), Positives = 93/237 (39%), Gaps = 10/237 (4%)
Query: 743 YRIGALVKYRCEKGYKVIGESLS-TCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSN 801
Y G + Y C+ GY G C G W T C C G +ENG V
Sbjct: 41 YEPGEEITYSCKPGYVSRGGMRKFICPLTGLWPINTLKCTPRVCPFAGILENGAVRY--- 97
Query: 802 ATF-YGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLV 860
TF Y T + C+ + L G C E G WS E P+C I CP PS A +
Sbjct: 98 TTFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAPIICPPPSIPTFATLRVYK 157
Query: 861 VT--STLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKI 918
+ + A ++C + + G+ T TC + G W +P C + C P +NG +
Sbjct: 158 PSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWT-KLPECREVKCPFPSRPDNGFV 216
Query: 919 VISNGSTL-FGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCELATNEAVDSGT 974
TL + + C Y GP +C G WS PSC+ + V T
Sbjct: 217 NYPAKPTLYYKDKATFGCHDGYSLDGPEEIECTKLGNWSA-MPSCKASCKLPVKKAT 272
Score = 83.8 bits (198), Expect = 3e-15
Identities = 69/259 (26%), Positives = 106/259 (40%), Gaps = 23/259 (8%)
Query: 587 SCPEPE-VPSGGYMEAFDYYVHST-INFHCEAGH-KLIGEPNLVCQQDGEWSGDSPTCEY 643
+CP+P+ +P + +Y I + C+ G+ G +C G W ++ C
Sbjct: 22 TCPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYVSRGGMRKFICPLTGLWPINTLKCTP 81
Query: 644 IDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEE 703
C L G + T + I +SC T + L G CTEE +WS P C
Sbjct: 82 RVCPFAGILENGAVRYT--TFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAP 139
Query: 704 IRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGES 763
I C P + + + V S G+ + YR A+ + C + + G
Sbjct: 140 IICPPPSIPTFATLRV--YKPSAGN-----------NSLYRDTAV--FECLPQHAMFGND 184
Query: 764 LSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNAT-FYGATAFYQCDENWELEGV 822
TC +G W+ P C+ V C P R +NG V P+ T +Y A + C + + L+G
Sbjct: 185 TITCTTHGNWT-KLPECREVKCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSLDGP 243
Query: 823 IRRMCQENGTWSLEPPICK 841
C + G WS P CK
Sbjct: 244 EEIECTKLGNWSAMPS-CK 261
Score = 77.4 bits (182), Expect = 3e-13
Identities = 68/270 (25%), Positives = 103/270 (38%), Gaps = 30/270 (11%)
Query: 646 CGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRR-TCTEEFQWSDSSPRCEEI 704
C K LP+ T+ L G I YSC Y G +R+ C W ++ +C
Sbjct: 23 CPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYVSRGGMRKFICPLTGLWPINTLKCTPR 82
Query: 705 RCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESL 764
C + E V T T+ + + C G+ + G
Sbjct: 83 VCPFAGILENGAVRYT---------------------TFEYPNTISFSCNTGFYLNGADS 121
Query: 765 STCEDNGQWSGTTPTCQYVDCGNPG--RIENGKVTLPS--NATFYGATAFYQCDENWELE 820
+ C + G+WS P C + C P +V PS N + Y TA ++C +
Sbjct: 122 AKCTEEGKWSPELPVCAPIICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMF 181
Query: 821 GVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYN 880
G C +G W+ + P C+E+ CP PS + G TL +A + C GY+
Sbjct: 182 GNDTITCTTHGNWT-KLPECREVKCPFPS-RPDNGFVNYPAKPTLYYKDKATFGCHDGYS 239
Query: 881 LKGHQTRTCISKGQWNGTVPVCIPIDCRSP 910
L G + C G W+ +P C C+ P
Sbjct: 240 LDGPEEIECTKLGNWS-AMPSC-KASCKLP 267
Score = 66.9 bits (156), Expect = 4e-10
Identities = 49/190 (25%), Positives = 73/190 (38%), Gaps = 10/190 (5%)
Query: 350 PPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYV 409
P C L N + ++ + I + C G L G S C ++G WS P C +
Sbjct: 81 PRVCPFAGILENGAVRYTTFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAPI 140
Query: 410 NCGGLTPIEDGDVAL----IDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPR 465
C + + + N + + A++ C + GN TC G W + P
Sbjct: 141 ICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWT-KLPE 199
Query: 466 CLFDWCPDPPAVSNASVTVNGHKA---GSLASYTCENGHILSGSTSVTCTLGGAWSGVPP 522
C CP P N V A++ C +G+ L G + CT G WS + P
Sbjct: 200 CREVKCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSLDGPEEIECTKLGNWSAM-P 258
Query: 523 SCKYVNCGTP 532
SCK +C P
Sbjct: 259 SCK-ASCKLP 267
Score = 43.6 bits (98), Expect = 0.004
Identities = 22/77 (28%), Positives = 36/77 (46%), Gaps = 3/77 (3%)
Query: 1 RCGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGT 60
+C P+ P N V+ P + + A + C +GY L G + ECT G+W+ P
Sbjct: 204 KCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSLDGPEEIECTKLGNWSAMP---SC 260
Query: 61 NVAFRKPANQSTTVRGG 77
+ + P ++T V G
Sbjct: 261 KASCKLPVKKATVVYQG 277
Score = 32.7 bits (71), Expect = 7.4
Identities = 20/57 (35%), Positives = 28/57 (49%), Gaps = 3/57 (5%)
Query: 2 CGHPAVPPNA--RVSIPNE-ENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEP 55
C P++P A RV P+ N + AV+EC + +FG CT G+WT P
Sbjct: 142 CPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWTKLP 198
Score = 32.3 bits (70), Expect = 9.7
Identities = 12/30 (40%), Positives = 17/30 (56%)
Query: 29 YECDEGYELFGARQRECTLRGDWTLEPPFC 58
+ C+ G+ L GA +CT G W+ E P C
Sbjct: 108 FSCNTGFYLNGADSAKCTEEGKWSPELPVC 137
>X53595-1|CAA37664.1| 345|Homo sapiens beta-2-glycoprotein I
protein.
Length = 345
Score = 97.9 bits (233), Expect = 2e-19
Identities = 62/228 (27%), Positives = 92/228 (40%), Gaps = 13/228 (5%)
Query: 432 GARALYSCRENFTLVGNPER-TCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAG 490
G YSC+ + G + C G+W +C CP + N +V +
Sbjct: 44 GEEITYSCKPGYVSRGGMRKFICPLTGLWPINTLKCTPRVCPFAGILENGAVRYTTFEYP 103
Query: 491 SLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTIHKGSFVLI-----NGT 545
+ S++C G L+G+ S CT G WS P C + C P+I + + +
Sbjct: 104 NTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAPIICPPPSIPTFATLRVYKPSAGNN 163
Query: 546 TTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGG---YMEAF 602
+ Y A F C P + + G + + C G W+ +P C CP P P G Y
Sbjct: 164 SLYRDTAVFECLPQHAMFGNDTITCTTHGNWT-KLPECREVKCPFPSRPDNGFVNYPAKP 222
Query: 603 DYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLP 650
Y F C G+ L G + C + G WS P+C+ C KLP
Sbjct: 223 TLYYKDKATFGCHDGYSLDGPEEIECTKLGNWSA-MPSCK-ASC-KLP 267
Score = 92.3 bits (219), Expect = 9e-18
Identities = 64/251 (25%), Positives = 100/251 (39%), Gaps = 16/251 (6%)
Query: 471 CPDPPAVSNASVTV--NGHKAGSLASYTCENGHILSGST-SVTCTLGGAWSGVPPSCKYV 527
CP P + ++V ++ G +Y+C+ G++ G C L G W C
Sbjct: 23 CPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYVSRGGMRKFICPLTGLWPINTLKCTPR 82
Query: 528 NCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTS 587
C I + V T Y + F+C ++LNGA+ C +GKWS ++P C
Sbjct: 83 VCPFAGILENGAVRYT-TFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAPII 141
Query: 588 CPEPEVPSGGYMEAF------DYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTC 641
CP P +P+ + + + T F C H + G + C G W+ P C
Sbjct: 142 CPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWT-KLPEC 200
Query: 642 EYIDCGKLPTLP-YGTMEL-LNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSP 699
+ C P+ P G + T + + C Y L GP CT+ WS + P
Sbjct: 201 REVKC-PFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSLDGPEEIECTKLGNWS-AMP 258
Query: 700 RCEEIRCSDPI 710
C + C P+
Sbjct: 259 SC-KASCKLPV 268
Score = 89.8 bits (213), Expect = 5e-17
Identities = 68/237 (28%), Positives = 93/237 (39%), Gaps = 10/237 (4%)
Query: 743 YRIGALVKYRCEKGYKVIGESLS-TCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSN 801
Y G + Y C+ GY G C G W T C C G +ENG V
Sbjct: 41 YEPGEEITYSCKPGYVSRGGMRKFICPLTGLWPINTLKCTPRVCPFAGILENGAVRY--- 97
Query: 802 ATF-YGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLV 860
TF Y T + C+ + L G C E G WS E P+C I CP PS A +
Sbjct: 98 TTFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAPIICPPPSIPTFATLRVYK 157
Query: 861 VT--STLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKI 918
+ + A ++C + + G+ T TC + G W +P C + C P +NG +
Sbjct: 158 PSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWT-KLPECREVKCPFPSRPDNGFV 216
Query: 919 VISNGSTL-FGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCELATNEAVDSGT 974
TL + + C Y GP +C G WS PSC+ + V T
Sbjct: 217 NYPAKPTLYYKDKATFGCHDGYSLDGPEEIECTKLGNWSA-MPSCKASCKLPVKKAT 272
Score = 83.8 bits (198), Expect = 3e-15
Identities = 69/259 (26%), Positives = 106/259 (40%), Gaps = 23/259 (8%)
Query: 587 SCPEPE-VPSGGYMEAFDYYVHST-INFHCEAGH-KLIGEPNLVCQQDGEWSGDSPTCEY 643
+CP+P+ +P + +Y I + C+ G+ G +C G W ++ C
Sbjct: 22 TCPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYVSRGGMRKFICPLTGLWPINTLKCTP 81
Query: 644 IDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEE 703
C L G + T + I +SC T + L G CTEE +WS P C
Sbjct: 82 RVCPFAGILENGAVRYT--TFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAP 139
Query: 704 IRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGES 763
I C P + + + V S G+ + YR A+ + C + + G
Sbjct: 140 IICPPPSIPTFATLRV--YKPSAGN-----------NSLYRDTAV--FECLPQHAMFGND 184
Query: 764 LSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNAT-FYGATAFYQCDENWELEGV 822
TC +G W+ P C+ V C P R +NG V P+ T +Y A + C + + L+G
Sbjct: 185 TITCTTHGNWT-KLPECREVKCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSLDGP 243
Query: 823 IRRMCQENGTWSLEPPICK 841
C + G WS P CK
Sbjct: 244 EEIECTKLGNWSAMPS-CK 261
Score = 77.4 bits (182), Expect = 3e-13
Identities = 68/270 (25%), Positives = 103/270 (38%), Gaps = 30/270 (11%)
Query: 646 CGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRR-TCTEEFQWSDSSPRCEEI 704
C K LP+ T+ L G I YSC Y G +R+ C W ++ +C
Sbjct: 23 CPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYVSRGGMRKFICPLTGLWPINTLKCTPR 82
Query: 705 RCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESL 764
C + E V T T+ + + C G+ + G
Sbjct: 83 VCPFAGILENGAVRYT---------------------TFEYPNTISFSCNTGFYLNGADS 121
Query: 765 STCEDNGQWSGTTPTCQYVDCGNPG--RIENGKVTLPS--NATFYGATAFYQCDENWELE 820
+ C + G+WS P C + C P +V PS N + Y TA ++C +
Sbjct: 122 AKCTEEGKWSPELPVCAPIICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMF 181
Query: 821 GVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYN 880
G C +G W+ + P C+E+ CP PS + G TL +A + C GY+
Sbjct: 182 GNDTITCTTHGNWT-KLPECREVKCPFPS-RPDNGFVNYPAKPTLYYKDKATFGCHDGYS 239
Query: 881 LKGHQTRTCISKGQWNGTVPVCIPIDCRSP 910
L G + C G W+ +P C C+ P
Sbjct: 240 LDGPEEIECTKLGNWS-AMPSC-KASCKLP 267
Score = 66.9 bits (156), Expect = 4e-10
Identities = 49/190 (25%), Positives = 73/190 (38%), Gaps = 10/190 (5%)
Query: 350 PPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYV 409
P C L N + ++ + I + C G L G S C ++G WS P C +
Sbjct: 81 PRVCPFAGILENGAVRYTTFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAPI 140
Query: 410 NCGGLTPIEDGDVAL----IDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPR 465
C + + + N + + A++ C + GN TC G W + P
Sbjct: 141 ICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWT-KLPE 199
Query: 466 CLFDWCPDPPAVSNASVTVNGHKA---GSLASYTCENGHILSGSTSVTCTLGGAWSGVPP 522
C CP P N V A++ C +G+ L G + CT G WS + P
Sbjct: 200 CREVKCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSLDGPEEIECTKLGNWSAM-P 258
Query: 523 SCKYVNCGTP 532
SCK +C P
Sbjct: 259 SCK-ASCKLP 267
Score = 43.6 bits (98), Expect = 0.004
Identities = 22/77 (28%), Positives = 36/77 (46%), Gaps = 3/77 (3%)
Query: 1 RCGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGT 60
+C P+ P N V+ P + + A + C +GY L G + ECT G+W+ P
Sbjct: 204 KCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSLDGPEEIECTKLGNWSAMP---SC 260
Query: 61 NVAFRKPANQSTTVRGG 77
+ + P ++T V G
Sbjct: 261 KASCKLPVKKATVVYQG 277
Score = 32.7 bits (71), Expect = 7.4
Identities = 20/57 (35%), Positives = 28/57 (49%), Gaps = 3/57 (5%)
Query: 2 CGHPAVPPNA--RVSIPNE-ENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEP 55
C P++P A RV P+ N + AV+EC + +FG CT G+WT P
Sbjct: 142 CPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWTKLP 198
Score = 32.3 bits (70), Expect = 9.7
Identities = 12/30 (40%), Positives = 17/30 (56%)
Query: 29 YECDEGYELFGARQRECTLRGDWTLEPPFC 58
+ C+ G+ L GA +CT G W+ E P C
Sbjct: 108 FSCNTGFYLNGADSAKCTEEGKWSPELPVC 137
>BC000567-1|AAH00567.1| 809|Homo sapiens SEZ6L2 protein protein.
Length = 809
Score = 97.9 bits (233), Expect = 2e-19
Identities = 65/195 (33%), Positives = 88/195 (45%), Gaps = 16/195 (8%)
Query: 462 EAPRCLFDWCPD--PPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSG 519
E PR D CP+ PP + + G++ +Y CE G+ L GS +TC +WS
Sbjct: 523 EVPRN--DTCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSA 580
Query: 520 VPPSC-KYVNCGTP-TIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVC-NRD--- 573
PP+C K + C P I G + GS Q+ C P Y L GA L C +RD
Sbjct: 581 APPACQKIMTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGT 640
Query: 574 GKWSYDIPSCEL--TSCPEPEVPSGGYMEAF--DYYVHSTINFHCEAGHKLIGEPNLVC- 628
KWS +P C L C P VP GY + Y ++ F C G +LIGE + C
Sbjct: 641 PKWSDRVPKCALKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCV 700
Query: 629 -QQDGEWSGDSPTCE 642
+W+ P C+
Sbjct: 701 PGHPSQWTSQPPLCK 715
Score = 95.5 bits (227), Expect = 9e-19
Identities = 75/244 (30%), Positives = 113/244 (46%), Gaps = 41/244 (16%)
Query: 646 CGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEI- 704
C +LP +G +G G+V+ Y C Y L+G TC + WS + P C++I
Sbjct: 530 CPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKIM 589
Query: 705 RCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESL 764
C+DP + ++GH RT+ D G + +G+ V+YRC GY + G ++
Sbjct: 590 TCADP------------GEIANGH---RTAS--DAG--FPVGSHVQYRCLPGYSLEGAAM 630
Query: 765 STC--EDNG--QWSGTTPTC--QYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWE 818
TC D G +WS P C +Y C NPG ENG TL + G + + C E +E
Sbjct: 631 LTCYSRDTGTPKWSDRVPKCALKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFE 690
Query: 819 LEGVIRRMCQEN--GTWSLEPPICK------------EIT-CPDPSAQIKAGSGLLVVTS 863
L G + C W+ +PP+CK E+T DPS Q++ G+ L +
Sbjct: 691 LIGEVTITCVPGHPSQWTSQPPLCKVAYEELLDNRKLEVTQTTDPSRQLEGGNLALAILL 750
Query: 864 TLSI 867
L +
Sbjct: 751 PLGL 754
Score = 87.0 bits (206), Expect = 3e-16
Identities = 52/176 (29%), Positives = 85/176 (48%), Gaps = 11/176 (6%)
Query: 806 GATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEI-TCPDPSAQIKAGSGLLVVTST 864
G YQC+ +EL G CQ + +WS PP C++I TC DP +I G +
Sbjct: 551 GTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKIMTCADPG-EIANGHRT-ASDAG 608
Query: 865 LSIGGEAHYQCERGYNLKGHQTRTCISKG----QWNGTVPVC-IPID-CRSPGNIENGKI 918
+G Y+C GY+L+G TC S+ +W+ VP C + + C +PG ENG
Sbjct: 609 FPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPKCALKYEPCLNPGVPENGYQ 668
Query: 919 VISNGSTLFGSSVEYYCLSQYQRVGPFLRKCL--DDGRWSGEEPSCELATNEAVDS 972
+ G S+ ++C ++ +G C+ +W+ + P C++A E +D+
Sbjct: 669 TLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPLCKVAYEELLDN 724
Score = 80.6 bits (190), Expect = 3e-14
Identities = 59/191 (30%), Positives = 81/191 (42%), Gaps = 16/191 (8%)
Query: 346 CQYLPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPS 405
C LPP P+ T G D G+ + Y+C G+ LLG C+ D WS APP+
Sbjct: 530 CPELPP----PEWGWRTASHG-DLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPA 584
Query: 406 C-KYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTC--GDEGI--WD 460
C K + C I +G D G+ Y C ++L G TC D G W
Sbjct: 585 CQKIMTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWS 644
Query: 461 GEAPRCL--FDWCPDPPAVSNASVTVNGH--KAGSLASYTCENGHILSGSTSVTCTLG-- 514
P+C ++ C +P N T+ H +AG + C G L G ++TC G
Sbjct: 645 DRVPKCALKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHP 704
Query: 515 GAWSGVPPSCK 525
W+ PP CK
Sbjct: 705 SQWTSQPPLCK 715
Score = 77.0 bits (181), Expect = 3e-13
Identities = 63/227 (27%), Positives = 97/227 (42%), Gaps = 32/227 (14%)
Query: 587 SCPEPEVPSGGYMEAF--DYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYI 644
+CPE P G+ A D + + + CE G++L+G L CQ D WS P C+ I
Sbjct: 529 TCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKI 588
Query: 645 -DCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTC----TEEFQWSDSSP 699
C + G + +GS +QY C Y L G TC T +WSD P
Sbjct: 589 MTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVP 648
Query: 700 RC--EEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGY 757
+C + C +P V E TL + + Y+ G +++ C +G+
Sbjct: 649 KCALKYEPCLNPGVPENGY-----------QTLYK--------HHYQAGESLRFFCYEGF 689
Query: 758 KVIGESLSTCEDN--GQWSGTTPTCQ--YVDCGNPGRIENGKVTLPS 800
++IGE TC QW+ P C+ Y + + ++E + T PS
Sbjct: 690 ELIGEVTITCVPGHPSQWTSQPPLCKVAYEELLDNRKLEVTQTTDPS 736
Score = 65.3 bits (152), Expect = 1e-09
Identities = 38/106 (35%), Positives = 45/106 (42%), Gaps = 5/106 (4%)
Query: 873 YQCERGYNLKGHQTRTCISKGQWNGTVPVCIPI-DCRSPGNIENGKIVISNGSTLFGSSV 931
YQCE GY L G TC W+ P C I C PG I NG S+ GS V
Sbjct: 556 YQCEPGYELLGSDILTCQWDLSWSAAPPACQKIMTCADPGEIANGHRTASDAGFPVGSHV 615
Query: 932 EYYCLSQYQRVGPFLRKCL--DDG--RWSGEEPSCELATNEAVDSG 973
+Y CL Y G + C D G +WS P C L ++ G
Sbjct: 616 QYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPKCALKYEPCLNPG 661
Score = 49.6 bits (113), Expect = 6e-05
Identities = 23/65 (35%), Positives = 35/65 (53%), Gaps = 3/65 (4%)
Query: 585 LTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQD--GEWSGDSPTCE 642
L SC P P+ G + D + T FHC++G++L GE L+C W+G++P+C
Sbjct: 173 LLSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSC- 231
Query: 643 YIDCG 647
CG
Sbjct: 232 MASCG 236
Score = 45.2 bits (102), Expect = 0.001
Identities = 27/89 (30%), Positives = 43/89 (48%), Gaps = 5/89 (5%)
Query: 471 CPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLG--GAWSGVPPSCKYVN 528
C PP ++ V+V G A++ C++G+ L G ++ C G +W+G PSC +
Sbjct: 176 CGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSC-MAS 234
Query: 529 CGTPTIHKGSFVLINGTTTYGSIA-QFTC 556
CG TIH + I G++ TC
Sbjct: 235 CG-GTIHNATLGRIVSPEPGGAVGPNLTC 262
Score = 41.9 bits (94), Expect = 0.012
Identities = 21/62 (33%), Positives = 32/62 (51%), Gaps = 2/62 (3%)
Query: 860 VVTSTLSIGGEAHYQCERGYNLKGHQTRTCI--SKGQWNGTVPVCIPIDCRSPGNIENGK 917
V + L GG A + C+ GY L+G +T C+ ++ WNG P C+ + N G+
Sbjct: 187 VSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCMASCGGTIHNATLGR 246
Query: 918 IV 919
IV
Sbjct: 247 IV 248
Score = 41.1 bits (92), Expect = 0.021
Identities = 22/89 (24%), Positives = 35/89 (39%), Gaps = 4/89 (4%)
Query: 8 PPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTNVAFRKP 67
PP + +++ GT+ Y+C+ GYEL G+ C W+ PP C + P
Sbjct: 535 PPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKIMTCADP 594
Query: 68 ANQSTTVRGGAAANGNDGEKTTEHDRKRC 96
+ G + G H + RC
Sbjct: 595 GE----IANGHRTASDAGFPVGSHVQYRC 619
Score = 36.3 bits (80), Expect = 0.60
Identities = 18/64 (28%), Positives = 29/64 (45%), Gaps = 3/64 (4%)
Query: 352 TCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKD--GFWSGAPPSCKYV 409
+CG P + + + D G + C G+ L G+++ C W+G PSC
Sbjct: 175 SCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSC-MA 233
Query: 410 NCGG 413
+CGG
Sbjct: 234 SCGG 237
Score = 35.5 bits (78), Expect = 1.0
Identities = 20/59 (33%), Positives = 26/59 (44%), Gaps = 5/59 (8%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECT--LRGDWTLEPPFC 58
CG P P + VS+ + + G A + CD GY+L G C R W E P C
Sbjct: 176 CGFPPRPAHGDVSVTD---LHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSC 231
Score = 35.1 bits (77), Expect = 1.4
Identities = 22/67 (32%), Positives = 32/67 (47%), Gaps = 6/67 (8%)
Query: 777 TPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGT---W 833
T + CG P R +G V++ G TA + CD ++L+G +C NGT W
Sbjct: 168 TSPAYLLSCGFPPRPAHGDVSVTD--LHPGGTATFHCDSGYQLQGEETLICL-NGTRPSW 224
Query: 834 SLEPPIC 840
+ E P C
Sbjct: 225 NGETPSC 231
Score = 34.7 bits (76), Expect = 1.8
Identities = 19/59 (32%), Positives = 29/59 (49%), Gaps = 8/59 (13%)
Query: 746 GALVKYRCEKGYKVIGESLSTCEDNGQ--WSGTTPTCQYVDCGNPGRIEN---GKVTLP 799
G + C+ GY++ GE C + + W+G TP+C CG G I N G++ P
Sbjct: 195 GGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCM-ASCG--GTIHNATLGRIVSP 250
Score = 33.1 bits (72), Expect = 5.6
Identities = 16/42 (38%), Positives = 22/42 (52%), Gaps = 3/42 (7%)
Query: 549 GSIAQFTCEPDYWLNGAEELVCNRDGK--WSYDIPSCELTSC 588
G A F C+ Y L G E L+C + W+ + PSC + SC
Sbjct: 195 GGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSC-MASC 235
Score = 32.7 bits (71), Expect = 7.4
Identities = 19/72 (26%), Positives = 33/72 (45%), Gaps = 4/72 (5%)
Query: 905 IDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGR--WSGEEPSC 962
+ C P +G + +++ G + ++C S YQ G CL+ R W+GE PSC
Sbjct: 174 LSCGFPPRPAHGDVSVTDLHP--GGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSC 231
Query: 963 ELATNEAVDSGT 974
+ + + T
Sbjct: 232 MASCGGTIHNAT 243
>AK074998-1|BAC11345.1| 578|Homo sapiens protein ( Homo sapiens
cDNA FLJ90517 fis, clone NT2RP3004552, highly similar to
Type I transmembrane receptor. ).
Length = 578
Score = 97.9 bits (233), Expect = 2e-19
Identities = 65/195 (33%), Positives = 88/195 (45%), Gaps = 16/195 (8%)
Query: 462 EAPRCLFDWCPD--PPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSG 519
E PR D CP+ PP + + G++ +Y CE G+ L GS +TC +WS
Sbjct: 292 EVPRN--DTCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSA 349
Query: 520 VPPSC-KYVNCGTP-TIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVC-NRD--- 573
PP+C K + C P I G + GS Q+ C P Y L GA L C +RD
Sbjct: 350 APPACQKIMTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGT 409
Query: 574 GKWSYDIPSCEL--TSCPEPEVPSGGYMEAF--DYYVHSTINFHCEAGHKLIGEPNLVC- 628
KWS +P C L C P VP GY + Y ++ F C G +LIGE + C
Sbjct: 410 PKWSDRVPKCALKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCV 469
Query: 629 -QQDGEWSGDSPTCE 642
+W+ P C+
Sbjct: 470 PGHPSQWTSQPPLCK 484
Score = 95.5 bits (227), Expect = 9e-19
Identities = 75/244 (30%), Positives = 113/244 (46%), Gaps = 41/244 (16%)
Query: 646 CGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEI- 704
C +LP +G +G G+V+ Y C Y L+G TC + WS + P C++I
Sbjct: 299 CPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKIM 358
Query: 705 RCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESL 764
C+DP + ++GH RT+ D G + +G+ V+YRC GY + G ++
Sbjct: 359 TCADP------------GEIANGH---RTAS--DAG--FPVGSHVQYRCLPGYSLEGAAM 399
Query: 765 STC--EDNG--QWSGTTPTC--QYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWE 818
TC D G +WS P C +Y C NPG ENG TL + G + + C E +E
Sbjct: 400 LTCYSRDTGTPKWSDRVPKCALKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFE 459
Query: 819 LEGVIRRMCQEN--GTWSLEPPICK------------EIT-CPDPSAQIKAGSGLLVVTS 863
L G + C W+ +PP+CK E+T DPS Q++ G+ L +
Sbjct: 460 LIGEVTITCVPGHPSQWTSQPPLCKVAYEELLDNRKLEVTQTTDPSRQLEGGNLALAILL 519
Query: 864 TLSI 867
L +
Sbjct: 520 PLGL 523
Score = 87.0 bits (206), Expect = 3e-16
Identities = 52/176 (29%), Positives = 85/176 (48%), Gaps = 11/176 (6%)
Query: 806 GATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEI-TCPDPSAQIKAGSGLLVVTST 864
G YQC+ +EL G CQ + +WS PP C++I TC DP +I G +
Sbjct: 320 GTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKIMTCADPG-EIANGHRT-ASDAG 377
Query: 865 LSIGGEAHYQCERGYNLKGHQTRTCISKG----QWNGTVPVC-IPID-CRSPGNIENGKI 918
+G Y+C GY+L+G TC S+ +W+ VP C + + C +PG ENG
Sbjct: 378 FPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPKCALKYEPCLNPGVPENGYQ 437
Query: 919 VISNGSTLFGSSVEYYCLSQYQRVGPFLRKCL--DDGRWSGEEPSCELATNEAVDS 972
+ G S+ ++C ++ +G C+ +W+ + P C++A E +D+
Sbjct: 438 TLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPLCKVAYEELLDN 493
Score = 80.6 bits (190), Expect = 3e-14
Identities = 59/191 (30%), Positives = 81/191 (42%), Gaps = 16/191 (8%)
Query: 346 CQYLPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPS 405
C LPP P+ T G D G+ + Y+C G+ LLG C+ D WS APP+
Sbjct: 299 CPELPP----PEWGWRTASHG-DLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPA 353
Query: 406 C-KYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTC--GDEGI--WD 460
C K + C I +G D G+ Y C ++L G TC D G W
Sbjct: 354 CQKIMTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWS 413
Query: 461 GEAPRCL--FDWCPDPPAVSNASVTVNGH--KAGSLASYTCENGHILSGSTSVTCTLG-- 514
P+C ++ C +P N T+ H +AG + C G L G ++TC G
Sbjct: 414 DRVPKCALKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHP 473
Query: 515 GAWSGVPPSCK 525
W+ PP CK
Sbjct: 474 SQWTSQPPLCK 484
Score = 77.0 bits (181), Expect = 3e-13
Identities = 63/227 (27%), Positives = 97/227 (42%), Gaps = 32/227 (14%)
Query: 587 SCPEPEVPSGGYMEAF--DYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYI 644
+CPE P G+ A D + + + CE G++L+G L CQ D WS P C+ I
Sbjct: 298 TCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKI 357
Query: 645 -DCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTC----TEEFQWSDSSP 699
C + G + +GS +QY C Y L G TC T +WSD P
Sbjct: 358 MTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVP 417
Query: 700 RC--EEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGY 757
+C + C +P V E TL + + Y+ G +++ C +G+
Sbjct: 418 KCALKYEPCLNPGVPENGY-----------QTLYK--------HHYQAGESLRFFCYEGF 458
Query: 758 KVIGESLSTCEDN--GQWSGTTPTCQ--YVDCGNPGRIENGKVTLPS 800
++IGE TC QW+ P C+ Y + + ++E + T PS
Sbjct: 459 ELIGEVTITCVPGHPSQWTSQPPLCKVAYEELLDNRKLEVTQTTDPS 505
Score = 65.3 bits (152), Expect = 1e-09
Identities = 38/106 (35%), Positives = 45/106 (42%), Gaps = 5/106 (4%)
Query: 873 YQCERGYNLKGHQTRTCISKGQWNGTVPVCIPI-DCRSPGNIENGKIVISNGSTLFGSSV 931
YQCE GY L G TC W+ P C I C PG I NG S+ GS V
Sbjct: 325 YQCEPGYELLGSDILTCQWDLSWSAAPPACQKIMTCADPGEIANGHRTASDAGFPVGSHV 384
Query: 932 EYYCLSQYQRVGPFLRKCL--DDG--RWSGEEPSCELATNEAVDSG 973
+Y CL Y G + C D G +WS P C L ++ G
Sbjct: 385 QYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPKCALKYEPCLNPG 430
Score = 41.1 bits (92), Expect = 0.021
Identities = 22/89 (24%), Positives = 35/89 (39%), Gaps = 4/89 (4%)
Query: 8 PPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTNVAFRKP 67
PP + +++ GT+ Y+C+ GYEL G+ C W+ PP C + P
Sbjct: 304 PPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKIMTCADP 363
Query: 68 ANQSTTVRGGAAANGNDGEKTTEHDRKRC 96
+ G + G H + RC
Sbjct: 364 GE----IANGHRTASDAGFPVGSHVQYRC 388
>AJ245820-1|CAB57950.1| 853|Homo sapiens type I transmembrane
receptor protein.
Length = 853
Score = 97.9 bits (233), Expect = 2e-19
Identities = 65/195 (33%), Positives = 88/195 (45%), Gaps = 16/195 (8%)
Query: 462 EAPRCLFDWCPD--PPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSG 519
E PR D CP+ PP + + G++ +Y CE G+ L GS +TC +WS
Sbjct: 567 EVPRN--DTCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSA 624
Query: 520 VPPSC-KYVNCGTP-TIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVC-NRD--- 573
PP+C K + C P I G + GS Q+ C P Y L GA L C +RD
Sbjct: 625 APPACQKIMTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGT 684
Query: 574 GKWSYDIPSCEL--TSCPEPEVPSGGYMEAF--DYYVHSTINFHCEAGHKLIGEPNLVC- 628
KWS +P C L C P VP GY + Y ++ F C G +LIGE + C
Sbjct: 685 PKWSDRVPKCALKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCV 744
Query: 629 -QQDGEWSGDSPTCE 642
+W+ P C+
Sbjct: 745 PGHPSQWTSQPPLCK 759
Score = 95.5 bits (227), Expect = 9e-19
Identities = 75/244 (30%), Positives = 113/244 (46%), Gaps = 41/244 (16%)
Query: 646 CGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEI- 704
C +LP +G +G G+V+ Y C Y L+G TC + WS + P C++I
Sbjct: 574 CPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKIM 633
Query: 705 RCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESL 764
C+DP + ++GH RT+ D G + +G+ V+YRC GY + G ++
Sbjct: 634 TCADP------------GEIANGH---RTAS--DAG--FPVGSHVQYRCLPGYSLEGAAM 674
Query: 765 STC--EDNG--QWSGTTPTC--QYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWE 818
TC D G +WS P C +Y C NPG ENG TL + G + + C E +E
Sbjct: 675 LTCYSRDTGTPKWSDRVPKCALKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFE 734
Query: 819 LEGVIRRMCQEN--GTWSLEPPICK------------EIT-CPDPSAQIKAGSGLLVVTS 863
L G + C W+ +PP+CK E+T DPS Q++ G+ L +
Sbjct: 735 LIGEVTITCVPGHPSQWTSQPPLCKVAYEELLDNRKLEVTQTTDPSRQLEGGNLALAILL 794
Query: 864 TLSI 867
L +
Sbjct: 795 PLGL 798
Score = 87.0 bits (206), Expect = 3e-16
Identities = 52/176 (29%), Positives = 85/176 (48%), Gaps = 11/176 (6%)
Query: 806 GATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEI-TCPDPSAQIKAGSGLLVVTST 864
G YQC+ +EL G CQ + +WS PP C++I TC DP +I G +
Sbjct: 595 GTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKIMTCADPG-EIANGHRT-ASDAG 652
Query: 865 LSIGGEAHYQCERGYNLKGHQTRTCISKG----QWNGTVPVC-IPID-CRSPGNIENGKI 918
+G Y+C GY+L+G TC S+ +W+ VP C + + C +PG ENG
Sbjct: 653 FPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPKCALKYEPCLNPGVPENGYQ 712
Query: 919 VISNGSTLFGSSVEYYCLSQYQRVGPFLRKCL--DDGRWSGEEPSCELATNEAVDS 972
+ G S+ ++C ++ +G C+ +W+ + P C++A E +D+
Sbjct: 713 TLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWTSQPPLCKVAYEELLDN 768
Score = 80.6 bits (190), Expect = 3e-14
Identities = 59/191 (30%), Positives = 81/191 (42%), Gaps = 16/191 (8%)
Query: 346 CQYLPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPS 405
C LPP P+ T G D G+ + Y+C G+ LLG C+ D WS APP+
Sbjct: 574 CPELPP----PEWGWRTASHG-DLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPA 628
Query: 406 C-KYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTC--GDEGI--WD 460
C K + C I +G D G+ Y C ++L G TC D G W
Sbjct: 629 CQKIMTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWS 688
Query: 461 GEAPRCL--FDWCPDPPAVSNASVTVNGH--KAGSLASYTCENGHILSGSTSVTCTLG-- 514
P+C ++ C +P N T+ H +AG + C G L G ++TC G
Sbjct: 689 DRVPKCALKYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHP 748
Query: 515 GAWSGVPPSCK 525
W+ PP CK
Sbjct: 749 SQWTSQPPLCK 759
Score = 77.0 bits (181), Expect = 3e-13
Identities = 63/227 (27%), Positives = 97/227 (42%), Gaps = 32/227 (14%)
Query: 587 SCPEPEVPSGGYMEAF--DYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYI 644
+CPE P G+ A D + + + CE G++L+G L CQ D WS P C+ I
Sbjct: 573 TCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKI 632
Query: 645 -DCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTC----TEEFQWSDSSP 699
C + G + +GS +QY C Y L G TC T +WSD P
Sbjct: 633 MTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVP 692
Query: 700 RC--EEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGY 757
+C + C +P V E TL + + Y+ G +++ C +G+
Sbjct: 693 KCALKYEPCLNPGVPENGY-----------QTLYK--------HHYQAGESLRFFCYEGF 733
Query: 758 KVIGESLSTCEDN--GQWSGTTPTCQ--YVDCGNPGRIENGKVTLPS 800
++IGE TC QW+ P C+ Y + + ++E + T PS
Sbjct: 734 ELIGEVTITCVPGHPSQWTSQPPLCKVAYEELLDNRKLEVTQTTDPS 780
Score = 65.3 bits (152), Expect = 1e-09
Identities = 38/106 (35%), Positives = 45/106 (42%), Gaps = 5/106 (4%)
Query: 873 YQCERGYNLKGHQTRTCISKGQWNGTVPVCIPI-DCRSPGNIENGKIVISNGSTLFGSSV 931
YQCE GY L G TC W+ P C I C PG I NG S+ GS V
Sbjct: 600 YQCEPGYELLGSDILTCQWDLSWSAAPPACQKIMTCADPGEIANGHRTASDAGFPVGSHV 659
Query: 932 EYYCLSQYQRVGPFLRKCL--DDG--RWSGEEPSCELATNEAVDSG 973
+Y CL Y G + C D G +WS P C L ++ G
Sbjct: 660 QYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPKCALKYEPCLNPG 705
Score = 49.6 bits (113), Expect = 6e-05
Identities = 23/65 (35%), Positives = 35/65 (53%), Gaps = 3/65 (4%)
Query: 585 LTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQD--GEWSGDSPTCE 642
L SC P P+ G + D + T FHC++G++L GE L+C W+G++P+C
Sbjct: 217 LLSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSC- 275
Query: 643 YIDCG 647
CG
Sbjct: 276 MASCG 280
Score = 45.2 bits (102), Expect = 0.001
Identities = 27/89 (30%), Positives = 43/89 (48%), Gaps = 5/89 (5%)
Query: 471 CPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLG--GAWSGVPPSCKYVN 528
C PP ++ V+V G A++ C++G+ L G ++ C G +W+G PSC +
Sbjct: 220 CGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSC-MAS 278
Query: 529 CGTPTIHKGSFVLINGTTTYGSIA-QFTC 556
CG TIH + I G++ TC
Sbjct: 279 CG-GTIHNATLGRIVSPEPGGAVGPNLTC 306
Score = 41.9 bits (94), Expect = 0.012
Identities = 21/62 (33%), Positives = 32/62 (51%), Gaps = 2/62 (3%)
Query: 860 VVTSTLSIGGEAHYQCERGYNLKGHQTRTCI--SKGQWNGTVPVCIPIDCRSPGNIENGK 917
V + L GG A + C+ GY L+G +T C+ ++ WNG P C+ + N G+
Sbjct: 231 VSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCMASCGGTIHNATLGR 290
Query: 918 IV 919
IV
Sbjct: 291 IV 292
Score = 41.1 bits (92), Expect = 0.021
Identities = 22/89 (24%), Positives = 35/89 (39%), Gaps = 4/89 (4%)
Query: 8 PPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTNVAFRKP 67
PP + +++ GT+ Y+C+ GYEL G+ C W+ PP C + P
Sbjct: 579 PPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKIMTCADP 638
Query: 68 ANQSTTVRGGAAANGNDGEKTTEHDRKRC 96
+ G + G H + RC
Sbjct: 639 GE----IANGHRTASDAGFPVGSHVQYRC 663
Score = 36.3 bits (80), Expect = 0.60
Identities = 31/116 (26%), Positives = 46/116 (39%), Gaps = 7/116 (6%)
Query: 354 GSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGG 413
GSP L +L N +G V + P +LL +S + G + ++CG
Sbjct: 166 GSPG--LAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGGGFR-IHYQAYLLSCGF 222
Query: 414 LTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTC--GDEGIWDGEAPRCL 467
GDV++ D G A + C + L G C G W+GE P C+
Sbjct: 223 PPRPAHGDVSVTDLHP--GGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCM 276
Score = 36.3 bits (80), Expect = 0.60
Identities = 18/64 (28%), Positives = 29/64 (45%), Gaps = 3/64 (4%)
Query: 352 TCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKD--GFWSGAPPSCKYV 409
+CG P + + + D G + C G+ L G+++ C W+G PSC
Sbjct: 219 SCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSC-MA 277
Query: 410 NCGG 413
+CGG
Sbjct: 278 SCGG 281
Score = 35.5 bits (78), Expect = 1.0
Identities = 20/59 (33%), Positives = 26/59 (44%), Gaps = 5/59 (8%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECT--LRGDWTLEPPFC 58
CG P P + VS+ + + G A + CD GY+L G C R W E P C
Sbjct: 220 CGFPPRPAHGDVSVTD---LHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSC 275
Score = 34.7 bits (76), Expect = 1.8
Identities = 21/61 (34%), Positives = 31/61 (50%), Gaps = 6/61 (9%)
Query: 783 VDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGT---WSLEPPI 839
+ CG P R +G V++ G TA + CD ++L+G +C NGT W+ E P
Sbjct: 218 LSCGFPPRPAHGDVSVTD--LHPGGTATFHCDSGYQLQGEETLICL-NGTRPSWNGETPS 274
Query: 840 C 840
C
Sbjct: 275 C 275
Score = 34.7 bits (76), Expect = 1.8
Identities = 19/59 (32%), Positives = 29/59 (49%), Gaps = 8/59 (13%)
Query: 746 GALVKYRCEKGYKVIGESLSTCEDNGQ--WSGTTPTCQYVDCGNPGRIEN---GKVTLP 799
G + C+ GY++ GE C + + W+G TP+C CG G I N G++ P
Sbjct: 239 GGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSCM-ASCG--GTIHNATLGRIVSP 294
Score = 33.1 bits (72), Expect = 5.6
Identities = 16/42 (38%), Positives = 22/42 (52%), Gaps = 3/42 (7%)
Query: 549 GSIAQFTCEPDYWLNGAEELVCNRDGK--WSYDIPSCELTSC 588
G A F C+ Y L G E L+C + W+ + PSC + SC
Sbjct: 239 GGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSC-MASC 279
Score = 32.7 bits (71), Expect = 7.4
Identities = 19/72 (26%), Positives = 33/72 (45%), Gaps = 4/72 (5%)
Query: 905 IDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGR--WSGEEPSC 962
+ C P +G + +++ G + ++C S YQ G CL+ R W+GE PSC
Sbjct: 218 LSCGFPPRPAHGDVSVTDLHP--GGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPSC 275
Query: 963 ELATNEAVDSGT 974
+ + + T
Sbjct: 276 MASCGGTIHNAT 287
>M31516-1|AAA52169.1| 381|Homo sapiens decay-accelerating factor
protein.
Length = 381
Score = 97.5 bits (232), Expect = 2e-19
Identities = 65/228 (28%), Positives = 98/228 (42%), Gaps = 17/228 (7%)
Query: 748 LVKYRCEKGY-KVIGESLST-CEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFY 805
++ Y+CE+ + K+ GE S C QWS C C P R+ + + P Y
Sbjct: 60 VITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNR-SCEVPTRLNSASLKQPYITQNY 118
Query: 806 ---GATAFYQCDENWELEGVI--RRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLV 860
G Y+C + E + + C +N WS CK+ +CP+P +I+ +G +
Sbjct: 119 FPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPG-EIR--NGQID 175
Query: 861 VTSTLSIGGEAHYQCERGYNLKGHQTRTCISKG---QWNGTVPVCIPIDCRSPGNIENGK 917
V + G + C GY L G + C+ G QW+ +P C I C +P I+NG
Sbjct: 176 VPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGI 235
Query: 918 IVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCL---DDGRWSGEEPSC 962
I + SV Y C + +G C D+G WSG P C
Sbjct: 236 IQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPEC 283
Score = 95.9 bits (228), Expect = 7e-19
Identities = 68/249 (27%), Positives = 106/249 (42%), Gaps = 19/249 (7%)
Query: 471 CPDPPAVSNASVTVNGHKA---GSLASYTCENGHI-LSGST-SVTCTLGGAWSGVPPSCK 525
C PP V NA + G + ++ +Y CE + + G SV C G WS + C
Sbjct: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCN 95
Query: 526 YVNCGTPT-IHKGSFVLINGTTTY---GSIAQFTCEPDYWLNGA--EELVCNRDGKWSYD 579
+C PT ++ S T Y G++ ++ C P Y + +L C ++ KWS
Sbjct: 96 R-SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTA 154
Query: 580 IPSCELTSCPEP-EVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDG---EWS 635
+ C+ SCP P E+ +G +TI+F C G+KL G + C G +WS
Sbjct: 155 VEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWS 214
Query: 636 GDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCT---EEF 692
P C I C P + G ++ + Y+C + ++G CT +E
Sbjct: 215 DPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEG 274
Query: 693 QWSDSSPRC 701
+WS P C
Sbjct: 275 EWSGPPPEC 283
Score = 91.5 bits (217), Expect = 2e-17
Identities = 78/271 (28%), Positives = 111/271 (40%), Gaps = 35/271 (12%)
Query: 645 DCGKLPTLPYGTMELLNGTTHL--GSVIQYSCTTNYRLVGPVRRT--CTEEFQWSDSSPR 700
DCG P +P L G T +VI Y C ++ + + + C + QWSD
Sbjct: 35 DCGLPPDVP-NAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEF 93
Query: 701 CEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVI 760
C C P N S I N + +G +V+Y C GY+
Sbjct: 94 CNR-SCEVPTRL---------NSASLKQPYITQ-------NYFPVGTVVEYECRPGYRR- 135
Query: 761 GESLS---TCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENW 817
SLS TC N +WS C+ C NPG I NG++ +P F GAT + C+ +
Sbjct: 136 EPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILF-GATISFSCNTGY 194
Query: 818 ELEGVIRRMCQENGT---WSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQ 874
+L G C +G+ WS P C+EI CP P QI G + Y
Sbjct: 195 KLFGSTSSFCLISGSSVQWSDPLPECREIYCPAP-PQIDNGI-IQGERDHYGYRQSVTYA 252
Query: 875 CERGYNLKGHQTRTCI---SKGQWNGTVPVC 902
C +G+ + G + C +G+W+G P C
Sbjct: 253 CNKGFTMIGEHSIYCTVNNDEGEWSGPPPEC 283
Score = 85.4 bits (202), Expect = 1e-15
Identities = 70/271 (25%), Positives = 111/271 (40%), Gaps = 38/271 (14%)
Query: 528 NCGTPTIHKGSFVLINGTTTY--GSIAQFTCEPDYWLNGAEE--LVCNRDGKWSYDIPSC 583
+CG P + + G T++ ++ + CE + E+ ++C + +WS DI
Sbjct: 35 DCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWS-DIEEF 93
Query: 584 ELTSCPEP-EVPSGGYMEAF---DYY-VHSTINFHCEAGHKLIGE--PNLVCQQDGEWSG 636
SC P + S + + +Y+ V + + + C G++ P L C Q+ +WS
Sbjct: 94 CNRSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWST 153
Query: 637 DSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCT---EEFQ 693
C+ C + G +++ G G+ I +SC T Y+L G C Q
Sbjct: 154 AVEFCKKKSCPNPGEIRNGQIDVPGGIL-FGATISFSCNTGYKLFGSTSSFCLISGSSVQ 212
Query: 694 WSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRC 753
WSD P C EI C P + I+ +R H Y V Y C
Sbjct: 213 WSDPLPECREIYCPAPPQIDNGIIQ---GERDH----------------YGYRQSVTYAC 253
Query: 754 EKGYKVIGESLSTC---EDNGQWSGTTPTCQ 781
KG+ +IGE C D G+WSG P C+
Sbjct: 254 NKGFTMIGEHSIYCTVNNDEGEWSGPPPECR 284
Score = 85.4 bits (202), Expect = 1e-15
Identities = 64/248 (25%), Positives = 101/248 (40%), Gaps = 20/248 (8%)
Query: 413 GLTPIEDGDVALIDNRTTHGARAL--YSCRENFTLVGNPERT--CGDEGIWDGEAPRCLF 468
GL P ++ RT+ + Y C E+F + + + C W C
Sbjct: 37 GLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNR 96
Query: 469 DWCPDPPAVSNAS-----VTVNGHKAGSLASYTCENGHILSGSTS--VTCTLGGAWSGVP 521
C P +++AS +T N G++ Y C G+ S S +TC WS
Sbjct: 97 S-CEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAV 155
Query: 522 PSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDG---KWSY 578
CK +C P + + + G +G+ F+C Y L G+ C G +WS
Sbjct: 156 EFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSD 215
Query: 579 DIPSCELTSCP-EPEVPSGGYMEAFDYY-VHSTINFHCEAGHKLIGEPNLVC---QQDGE 633
+P C CP P++ +G D+Y ++ + C G +IGE ++ C +GE
Sbjct: 216 PLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGE 275
Query: 634 WSGDSPTC 641
WSG P C
Sbjct: 276 WSGPPPEC 283
Score = 78.6 bits (185), Expect = 1e-13
Identities = 65/242 (26%), Positives = 97/242 (40%), Gaps = 21/242 (8%)
Query: 317 GEQNCVVLDGGRGWLWNDVGCNLDYLHWICQYLPPTCGSPDKLLNTTILGNDYDVGSRIV 376
GE++ V+ G W + CN C+ PT + L I N + VG+ +
Sbjct: 74 GEKDSVICLKGSQWSDIEEFCNRS-----CEV--PTRLNSASLKQPYITQNYFPVGTVVE 126
Query: 377 YKCPEGHMLLGDKSRH--CKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRTTHGAR 434
Y+C G+ S C ++ WS A CK +C I +G + + GA
Sbjct: 127 YECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQID-VPGGILFGAT 185
Query: 435 ALYSCRENFTLVGNPERTC---GDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGS 491
+SC + L G+ C G W P C +CP PP + N + G
Sbjct: 186 ISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGY 245
Query: 492 LAS--YTCENGHILSGSTSVTCTLG---GAWSGVPPSCKYVNCGT---PTIHKGSFVLIN 543
S Y C G + G S+ CT+ G WSG PP C+ + + PT+ K + V +
Sbjct: 246 RQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTVQKPTTVNVP 305
Query: 544 GT 545
T
Sbjct: 306 TT 307
Score = 74.9 bits (176), Expect = 1e-12
Identities = 66/267 (24%), Positives = 113/267 (42%), Gaps = 38/267 (14%)
Query: 591 PEVPSGG-YMEAFDYYVHST-INFHCEAGH-KLIGEPN-LVCQQDGEWSGDSPTCEYIDC 646
P+VP+ +E + T I + CE K+ GE + ++C + +WS C C
Sbjct: 40 PDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNR-SC 98
Query: 647 GKLPT-LPYGTME---LLNGTTHLGSVIQYSCTTNYRLVGPV--RRTCTEEFQWSDSSPR 700
++PT L +++ + +G+V++Y C YR + + TC + +WS +
Sbjct: 99 -EVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEF 157
Query: 701 CEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVI 760
C++ C +P + V G GA + + C GYK+
Sbjct: 158 CKKKSCPNPGEIRNGQIDVPGG--------------------ILFGATISFSCNTGYKLF 197
Query: 761 GESLSTCEDNG---QWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENW 817
G + S C +G QWS P C+ + C P +I+NG + + Y + Y C++ +
Sbjct: 198 GSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGF 257
Query: 818 ELEGVIRRMCQEN---GTWSLEPPICK 841
+ G C N G WS PP C+
Sbjct: 258 TMIGEHSIYCTVNNDEGEWSGPPPECR 284
Score = 73.3 bits (172), Expect = 4e-12
Identities = 53/191 (27%), Positives = 82/191 (42%), Gaps = 17/191 (8%)
Query: 784 DCGNPGRIENGKVTLPSNATFYGATAF-YQCDENW-----ELEGVIRRMCQENGTWSLEP 837
DCG P + N + L +F T Y+C+E++ E + VI C + WS
Sbjct: 35 DCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVI---CLKGSQWSDIE 91
Query: 838 PICKEITCPDPSAQIKAGSGLLVVTST-LSIGGEAHYQCERGYNLKGHQTR--TCISKGQ 894
C +C P+ A +T +G Y+C GY + + TC+ +
Sbjct: 92 EFCNR-SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLK 150
Query: 895 WNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDG- 953
W+ V C C +PG I NG+I + G LFG+++ + C + Y+ G CL G
Sbjct: 151 WSTAVEFCKKKSCPNPGEIRNGQIDVP-GGILFGATISFSCNTGYKLFGSTSSFCLISGS 209
Query: 954 --RWSGEEPSC 962
+WS P C
Sbjct: 210 SVQWSDPLPEC 220
Score = 34.3 bits (75), Expect = 2.4
Identities = 17/60 (28%), Positives = 28/60 (46%), Gaps = 5/60 (8%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRG---DWTLEPPFC 58
C +P N ++ +P I+ G + C+ GY+LFG+ C + G W+ P C
Sbjct: 163 CPNPGEIRNGQIDVPG--GILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPEC 220
Score = 32.3 bits (70), Expect = 9.7
Identities = 16/59 (27%), Positives = 29/59 (49%), Gaps = 2/59 (3%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGY-ELFGARQRECTLRG-DWTLEPPFC 58
CG P PNA+ ++ + T+ Y+C+E + ++ G + L+G W+ FC
Sbjct: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFC 94
>M30142-1|AAA52168.1| 381|Homo sapiens decay-accelerating factor A
protein.
Length = 381
Score = 97.5 bits (232), Expect = 2e-19
Identities = 65/228 (28%), Positives = 98/228 (42%), Gaps = 17/228 (7%)
Query: 748 LVKYRCEKGY-KVIGESLST-CEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFY 805
++ Y+CE+ + K+ GE S C QWS C C P R+ + + P Y
Sbjct: 60 VITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNR-SCEVPTRLNSASLKQPYITQNY 118
Query: 806 ---GATAFYQCDENWELEGVI--RRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLV 860
G Y+C + E + + C +N WS CK+ +CP+P +I+ +G +
Sbjct: 119 FPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPG-EIR--NGQID 175
Query: 861 VTSTLSIGGEAHYQCERGYNLKGHQTRTCISKG---QWNGTVPVCIPIDCRSPGNIENGK 917
V + G + C GY L G + C+ G QW+ +P C I C +P I+NG
Sbjct: 176 VPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGI 235
Query: 918 IVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCL---DDGRWSGEEPSC 962
I + SV Y C + +G C D+G WSG P C
Sbjct: 236 IQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPEC 283
Score = 95.9 bits (228), Expect = 7e-19
Identities = 68/249 (27%), Positives = 106/249 (42%), Gaps = 19/249 (7%)
Query: 471 CPDPPAVSNASVTVNGHKA---GSLASYTCENGHI-LSGST-SVTCTLGGAWSGVPPSCK 525
C PP V NA + G + ++ +Y CE + + G SV C G WS + C
Sbjct: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCN 95
Query: 526 YVNCGTPT-IHKGSFVLINGTTTY---GSIAQFTCEPDYWLNGA--EELVCNRDGKWSYD 579
+C PT ++ S T Y G++ ++ C P Y + +L C ++ KWS
Sbjct: 96 R-SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTA 154
Query: 580 IPSCELTSCPEP-EVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDG---EWS 635
+ C+ SCP P E+ +G +TI+F C G+KL G + C G +WS
Sbjct: 155 VEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWS 214
Query: 636 GDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCT---EEF 692
P C I C P + G ++ + Y+C + ++G CT +E
Sbjct: 215 DPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEG 274
Query: 693 QWSDSSPRC 701
+WS P C
Sbjct: 275 EWSGPPPEC 283
Score = 91.5 bits (217), Expect = 2e-17
Identities = 78/271 (28%), Positives = 111/271 (40%), Gaps = 35/271 (12%)
Query: 645 DCGKLPTLPYGTMELLNGTTHL--GSVIQYSCTTNYRLVGPVRRT--CTEEFQWSDSSPR 700
DCG P +P L G T +VI Y C ++ + + + C + QWSD
Sbjct: 35 DCGLPPDVP-NAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEF 93
Query: 701 CEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVI 760
C C P N S I N + +G +V+Y C GY+
Sbjct: 94 CNR-SCEVPTRL---------NSASLKQPYITQ-------NYFPVGTVVEYECRPGYRR- 135
Query: 761 GESLS---TCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENW 817
SLS TC N +WS C+ C NPG I NG++ +P F GAT + C+ +
Sbjct: 136 EPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILF-GATISFSCNTGY 194
Query: 818 ELEGVIRRMCQENGT---WSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQ 874
+L G C +G+ WS P C+EI CP P QI G + Y
Sbjct: 195 KLFGSTSSFCLISGSSVQWSDPLPECREIYCPAP-PQIDNGI-IQGERDHYGYRQSVTYA 252
Query: 875 CERGYNLKGHQTRTCI---SKGQWNGTVPVC 902
C +G+ + G + C +G+W+G P C
Sbjct: 253 CNKGFTMIGEHSIYCTVNNDEGEWSGPPPEC 283
Score = 85.4 bits (202), Expect = 1e-15
Identities = 70/271 (25%), Positives = 111/271 (40%), Gaps = 38/271 (14%)
Query: 528 NCGTPTIHKGSFVLINGTTTY--GSIAQFTCEPDYWLNGAEE--LVCNRDGKWSYDIPSC 583
+CG P + + G T++ ++ + CE + E+ ++C + +WS DI
Sbjct: 35 DCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWS-DIEEF 93
Query: 584 ELTSCPEP-EVPSGGYMEAF---DYY-VHSTINFHCEAGHKLIGE--PNLVCQQDGEWSG 636
SC P + S + + +Y+ V + + + C G++ P L C Q+ +WS
Sbjct: 94 CNRSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWST 153
Query: 637 DSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCT---EEFQ 693
C+ C + G +++ G G+ I +SC T Y+L G C Q
Sbjct: 154 AVEFCKKKSCPNPGEIRNGQIDVPGGIL-FGATISFSCNTGYKLFGSTSSFCLISGSSVQ 212
Query: 694 WSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRC 753
WSD P C EI C P + I+ +R H Y V Y C
Sbjct: 213 WSDPLPECREIYCPAPPQIDNGIIQ---GERDH----------------YGYRQSVTYAC 253
Query: 754 EKGYKVIGESLSTC---EDNGQWSGTTPTCQ 781
KG+ +IGE C D G+WSG P C+
Sbjct: 254 NKGFTMIGEHSIYCTVNNDEGEWSGPPPECR 284
Score = 85.4 bits (202), Expect = 1e-15
Identities = 64/248 (25%), Positives = 101/248 (40%), Gaps = 20/248 (8%)
Query: 413 GLTPIEDGDVALIDNRTTHGARAL--YSCRENFTLVGNPERT--CGDEGIWDGEAPRCLF 468
GL P ++ RT+ + Y C E+F + + + C W C
Sbjct: 37 GLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNR 96
Query: 469 DWCPDPPAVSNAS-----VTVNGHKAGSLASYTCENGHILSGSTS--VTCTLGGAWSGVP 521
C P +++AS +T N G++ Y C G+ S S +TC WS
Sbjct: 97 S-CEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAV 155
Query: 522 PSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDG---KWSY 578
CK +C P + + + G +G+ F+C Y L G+ C G +WS
Sbjct: 156 EFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSD 215
Query: 579 DIPSCELTSCP-EPEVPSGGYMEAFDYY-VHSTINFHCEAGHKLIGEPNLVC---QQDGE 633
+P C CP P++ +G D+Y ++ + C G +IGE ++ C +GE
Sbjct: 216 PLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGE 275
Query: 634 WSGDSPTC 641
WSG P C
Sbjct: 276 WSGPPPEC 283
Score = 78.6 bits (185), Expect = 1e-13
Identities = 65/242 (26%), Positives = 97/242 (40%), Gaps = 21/242 (8%)
Query: 317 GEQNCVVLDGGRGWLWNDVGCNLDYLHWICQYLPPTCGSPDKLLNTTILGNDYDVGSRIV 376
GE++ V+ G W + CN C+ PT + L I N + VG+ +
Sbjct: 74 GEKDSVICLKGSQWSDIEEFCNRS-----CEV--PTRLNSASLKQPYITQNYFPVGTVVE 126
Query: 377 YKCPEGHMLLGDKSRH--CKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRTTHGAR 434
Y+C G+ S C ++ WS A CK +C I +G + + GA
Sbjct: 127 YECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQID-VPGGILFGAT 185
Query: 435 ALYSCRENFTLVGNPERTC---GDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGS 491
+SC + L G+ C G W P C +CP PP + N + G
Sbjct: 186 ISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGY 245
Query: 492 LAS--YTCENGHILSGSTSVTCTLG---GAWSGVPPSCKYVNCGT---PTIHKGSFVLIN 543
S Y C G + G S+ CT+ G WSG PP C+ + + PT+ K + V +
Sbjct: 246 RQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTVQKPTTVNVP 305
Query: 544 GT 545
T
Sbjct: 306 TT 307
Score = 74.9 bits (176), Expect = 1e-12
Identities = 66/267 (24%), Positives = 113/267 (42%), Gaps = 38/267 (14%)
Query: 591 PEVPSGG-YMEAFDYYVHST-INFHCEAGH-KLIGEPN-LVCQQDGEWSGDSPTCEYIDC 646
P+VP+ +E + T I + CE K+ GE + ++C + +WS C C
Sbjct: 40 PDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNR-SC 98
Query: 647 GKLPT-LPYGTME---LLNGTTHLGSVIQYSCTTNYRLVGPV--RRTCTEEFQWSDSSPR 700
++PT L +++ + +G+V++Y C YR + + TC + +WS +
Sbjct: 99 -EVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEF 157
Query: 701 CEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVI 760
C++ C +P + V G GA + + C GYK+
Sbjct: 158 CKKKSCPNPGEIRNGQIDVPGG--------------------ILFGATISFSCNTGYKLF 197
Query: 761 GESLSTCEDNG---QWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENW 817
G + S C +G QWS P C+ + C P +I+NG + + Y + Y C++ +
Sbjct: 198 GSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGF 257
Query: 818 ELEGVIRRMCQEN---GTWSLEPPICK 841
+ G C N G WS PP C+
Sbjct: 258 TMIGEHSIYCTVNNDEGEWSGPPPECR 284
Score = 73.3 bits (172), Expect = 4e-12
Identities = 53/191 (27%), Positives = 82/191 (42%), Gaps = 17/191 (8%)
Query: 784 DCGNPGRIENGKVTLPSNATFYGATAF-YQCDENW-----ELEGVIRRMCQENGTWSLEP 837
DCG P + N + L +F T Y+C+E++ E + VI C + WS
Sbjct: 35 DCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVI---CLKGSQWSDIE 91
Query: 838 PICKEITCPDPSAQIKAGSGLLVVTST-LSIGGEAHYQCERGYNLKGHQTR--TCISKGQ 894
C +C P+ A +T +G Y+C GY + + TC+ +
Sbjct: 92 EFCNR-SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLK 150
Query: 895 WNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDG- 953
W+ V C C +PG I NG+I + G LFG+++ + C + Y+ G CL G
Sbjct: 151 WSTAVEFCKKKSCPNPGEIRNGQIDVP-GGILFGATISFSCNTGYKLFGSTSSFCLISGS 209
Query: 954 --RWSGEEPSC 962
+WS P C
Sbjct: 210 SVQWSDPLPEC 220
Score = 34.3 bits (75), Expect = 2.4
Identities = 17/60 (28%), Positives = 28/60 (46%), Gaps = 5/60 (8%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRG---DWTLEPPFC 58
C +P N ++ +P I+ G + C+ GY+LFG+ C + G W+ P C
Sbjct: 163 CPNPGEIRNGQIDVPG--GILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPEC 220
Score = 32.3 bits (70), Expect = 9.7
Identities = 16/59 (27%), Positives = 29/59 (49%), Gaps = 2/59 (3%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGY-ELFGARQRECTLRG-DWTLEPPFC 58
CG P PNA+ ++ + T+ Y+C+E + ++ G + L+G W+ FC
Sbjct: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFC 94
>BT007159-1|AAP35823.1| 381|Homo sapiens decay accelerating factor
for complement (CD55, Cromer blood group system)
protein.
Length = 381
Score = 97.5 bits (232), Expect = 2e-19
Identities = 65/228 (28%), Positives = 98/228 (42%), Gaps = 17/228 (7%)
Query: 748 LVKYRCEKGY-KVIGESLST-CEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFY 805
++ Y+CE+ + K+ GE S C QWS C C P R+ + + P Y
Sbjct: 60 VITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNR-SCEVPTRLNSASLKQPYITQNY 118
Query: 806 ---GATAFYQCDENWELEGVI--RRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLV 860
G Y+C + E + + C +N WS CK+ +CP+P +I+ +G +
Sbjct: 119 FPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPG-EIR--NGQID 175
Query: 861 VTSTLSIGGEAHYQCERGYNLKGHQTRTCISKG---QWNGTVPVCIPIDCRSPGNIENGK 917
V + G + C GY L G + C+ G QW+ +P C I C +P I+NG
Sbjct: 176 VPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGI 235
Query: 918 IVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCL---DDGRWSGEEPSC 962
I + SV Y C + +G C D+G WSG P C
Sbjct: 236 IQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPEC 283
Score = 95.9 bits (228), Expect = 7e-19
Identities = 68/249 (27%), Positives = 106/249 (42%), Gaps = 19/249 (7%)
Query: 471 CPDPPAVSNASVTVNGHKA---GSLASYTCENGHI-LSGST-SVTCTLGGAWSGVPPSCK 525
C PP V NA + G + ++ +Y CE + + G SV C G WS + C
Sbjct: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCN 95
Query: 526 YVNCGTPT-IHKGSFVLINGTTTY---GSIAQFTCEPDYWLNGA--EELVCNRDGKWSYD 579
+C PT ++ S T Y G++ ++ C P Y + +L C ++ KWS
Sbjct: 96 R-SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTA 154
Query: 580 IPSCELTSCPEP-EVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDG---EWS 635
+ C+ SCP P E+ +G +TI+F C G+KL G + C G +WS
Sbjct: 155 VEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWS 214
Query: 636 GDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCT---EEF 692
P C I C P + G ++ + Y+C + ++G CT +E
Sbjct: 215 DPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEG 274
Query: 693 QWSDSSPRC 701
+WS P C
Sbjct: 275 EWSGPPPEC 283
Score = 91.5 bits (217), Expect = 2e-17
Identities = 78/271 (28%), Positives = 111/271 (40%), Gaps = 35/271 (12%)
Query: 645 DCGKLPTLPYGTMELLNGTTHL--GSVIQYSCTTNYRLVGPVRRT--CTEEFQWSDSSPR 700
DCG P +P L G T +VI Y C ++ + + + C + QWSD
Sbjct: 35 DCGLPPDVP-NAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEF 93
Query: 701 CEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVI 760
C C P N S I N + +G +V+Y C GY+
Sbjct: 94 CNR-SCEVPTRL---------NSASLKQPYITQ-------NYFPVGTVVEYECRPGYRR- 135
Query: 761 GESLS---TCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENW 817
SLS TC N +WS C+ C NPG I NG++ +P F GAT + C+ +
Sbjct: 136 EPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILF-GATISFSCNTGY 194
Query: 818 ELEGVIRRMCQENGT---WSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQ 874
+L G C +G+ WS P C+EI CP P QI G + Y
Sbjct: 195 KLFGSTSSFCLISGSSVQWSDPLPECREIYCPAP-PQIDNGI-IQGERDHYGYRQSVTYA 252
Query: 875 CERGYNLKGHQTRTCI---SKGQWNGTVPVC 902
C +G+ + G + C +G+W+G P C
Sbjct: 253 CNKGFTMIGEHSIYCTVNNDEGEWSGPPPEC 283
Score = 85.4 bits (202), Expect = 1e-15
Identities = 70/271 (25%), Positives = 111/271 (40%), Gaps = 38/271 (14%)
Query: 528 NCGTPTIHKGSFVLINGTTTY--GSIAQFTCEPDYWLNGAEE--LVCNRDGKWSYDIPSC 583
+CG P + + G T++ ++ + CE + E+ ++C + +WS DI
Sbjct: 35 DCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWS-DIEEF 93
Query: 584 ELTSCPEP-EVPSGGYMEAF---DYY-VHSTINFHCEAGHKLIGE--PNLVCQQDGEWSG 636
SC P + S + + +Y+ V + + + C G++ P L C Q+ +WS
Sbjct: 94 CNRSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWST 153
Query: 637 DSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCT---EEFQ 693
C+ C + G +++ G G+ I +SC T Y+L G C Q
Sbjct: 154 AVEFCKKKSCPNPGEIRNGQIDVPGGIL-FGATISFSCNTGYKLFGSTSSFCLISGSSVQ 212
Query: 694 WSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRC 753
WSD P C EI C P + I+ +R H Y V Y C
Sbjct: 213 WSDPLPECREIYCPAPPQIDNGIIQ---GERDH----------------YGYRQSVTYAC 253
Query: 754 EKGYKVIGESLSTC---EDNGQWSGTTPTCQ 781
KG+ +IGE C D G+WSG P C+
Sbjct: 254 NKGFTMIGEHSIYCTVNNDEGEWSGPPPECR 284
Score = 85.4 bits (202), Expect = 1e-15
Identities = 64/248 (25%), Positives = 101/248 (40%), Gaps = 20/248 (8%)
Query: 413 GLTPIEDGDVALIDNRTTHGARAL--YSCRENFTLVGNPERT--CGDEGIWDGEAPRCLF 468
GL P ++ RT+ + Y C E+F + + + C W C
Sbjct: 37 GLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNR 96
Query: 469 DWCPDPPAVSNAS-----VTVNGHKAGSLASYTCENGHILSGSTS--VTCTLGGAWSGVP 521
C P +++AS +T N G++ Y C G+ S S +TC WS
Sbjct: 97 S-CEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAV 155
Query: 522 PSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDG---KWSY 578
CK +C P + + + G +G+ F+C Y L G+ C G +WS
Sbjct: 156 EFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSD 215
Query: 579 DIPSCELTSCP-EPEVPSGGYMEAFDYY-VHSTINFHCEAGHKLIGEPNLVC---QQDGE 633
+P C CP P++ +G D+Y ++ + C G +IGE ++ C +GE
Sbjct: 216 PLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGE 275
Query: 634 WSGDSPTC 641
WSG P C
Sbjct: 276 WSGPPPEC 283
Score = 78.6 bits (185), Expect = 1e-13
Identities = 65/242 (26%), Positives = 97/242 (40%), Gaps = 21/242 (8%)
Query: 317 GEQNCVVLDGGRGWLWNDVGCNLDYLHWICQYLPPTCGSPDKLLNTTILGNDYDVGSRIV 376
GE++ V+ G W + CN C+ PT + L I N + VG+ +
Sbjct: 74 GEKDSVICLKGSQWSDIEEFCNRS-----CEV--PTRLNSASLKQPYITQNYFPVGTVVE 126
Query: 377 YKCPEGHMLLGDKSRH--CKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRTTHGAR 434
Y+C G+ S C ++ WS A CK +C I +G + + GA
Sbjct: 127 YECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQID-VPGGILFGAT 185
Query: 435 ALYSCRENFTLVGNPERTC---GDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGS 491
+SC + L G+ C G W P C +CP PP + N + G
Sbjct: 186 ISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGY 245
Query: 492 LAS--YTCENGHILSGSTSVTCTLG---GAWSGVPPSCKYVNCGT---PTIHKGSFVLIN 543
S Y C G + G S+ CT+ G WSG PP C+ + + PT+ K + V +
Sbjct: 246 RQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTVQKPTTVNVP 305
Query: 544 GT 545
T
Sbjct: 306 TT 307
Score = 74.9 bits (176), Expect = 1e-12
Identities = 66/267 (24%), Positives = 113/267 (42%), Gaps = 38/267 (14%)
Query: 591 PEVPSGG-YMEAFDYYVHST-INFHCEAGH-KLIGEPN-LVCQQDGEWSGDSPTCEYIDC 646
P+VP+ +E + T I + CE K+ GE + ++C + +WS C C
Sbjct: 40 PDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNR-SC 98
Query: 647 GKLPT-LPYGTME---LLNGTTHLGSVIQYSCTTNYRLVGPV--RRTCTEEFQWSDSSPR 700
++PT L +++ + +G+V++Y C YR + + TC + +WS +
Sbjct: 99 -EVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEF 157
Query: 701 CEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVI 760
C++ C +P + V G GA + + C GYK+
Sbjct: 158 CKKKSCPNPGEIRNGQIDVPGG--------------------ILFGATISFSCNTGYKLF 197
Query: 761 GESLSTCEDNG---QWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENW 817
G + S C +G QWS P C+ + C P +I+NG + + Y + Y C++ +
Sbjct: 198 GSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGF 257
Query: 818 ELEGVIRRMCQEN---GTWSLEPPICK 841
+ G C N G WS PP C+
Sbjct: 258 TMIGEHSIYCTVNNDEGEWSGPPPECR 284
Score = 73.3 bits (172), Expect = 4e-12
Identities = 53/191 (27%), Positives = 82/191 (42%), Gaps = 17/191 (8%)
Query: 784 DCGNPGRIENGKVTLPSNATFYGATAF-YQCDENW-----ELEGVIRRMCQENGTWSLEP 837
DCG P + N + L +F T Y+C+E++ E + VI C + WS
Sbjct: 35 DCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVI---CLKGSQWSDIE 91
Query: 838 PICKEITCPDPSAQIKAGSGLLVVTST-LSIGGEAHYQCERGYNLKGHQTR--TCISKGQ 894
C +C P+ A +T +G Y+C GY + + TC+ +
Sbjct: 92 EFCNR-SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLK 150
Query: 895 WNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDG- 953
W+ V C C +PG I NG+I + G LFG+++ + C + Y+ G CL G
Sbjct: 151 WSTAVEFCKKKSCPNPGEIRNGQIDVP-GGILFGATISFSCNTGYKLFGSTSSFCLISGS 209
Query: 954 --RWSGEEPSC 962
+WS P C
Sbjct: 210 SVQWSDPLPEC 220
Score = 34.3 bits (75), Expect = 2.4
Identities = 17/60 (28%), Positives = 28/60 (46%), Gaps = 5/60 (8%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRG---DWTLEPPFC 58
C +P N ++ +P I+ G + C+ GY+LFG+ C + G W+ P C
Sbjct: 163 CPNPGEIRNGQIDVPG--GILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPEC 220
Score = 32.3 bits (70), Expect = 9.7
Identities = 16/59 (27%), Positives = 29/59 (49%), Gaps = 2/59 (3%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGY-ELFGARQRECTLRG-DWTLEPPFC 58
CG P PNA+ ++ + T+ Y+C+E + ++ G + L+G W+ FC
Sbjct: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFC 94
>BC001288-1|AAH01288.1| 381|Homo sapiens CD55 molecule, decay
accelerating factor for complement (Cromer blood group)
protein.
Length = 381
Score = 97.5 bits (232), Expect = 2e-19
Identities = 65/228 (28%), Positives = 98/228 (42%), Gaps = 17/228 (7%)
Query: 748 LVKYRCEKGY-KVIGESLST-CEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFY 805
++ Y+CE+ + K+ GE S C QWS C C P R+ + + P Y
Sbjct: 60 VITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNR-SCEVPTRLNSASLKQPYITQNY 118
Query: 806 ---GATAFYQCDENWELEGVI--RRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLV 860
G Y+C + E + + C +N WS CK+ +CP+P +I+ +G +
Sbjct: 119 FPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPG-EIR--NGQID 175
Query: 861 VTSTLSIGGEAHYQCERGYNLKGHQTRTCISKG---QWNGTVPVCIPIDCRSPGNIENGK 917
V + G + C GY L G + C+ G QW+ +P C I C +P I+NG
Sbjct: 176 VPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGI 235
Query: 918 IVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCL---DDGRWSGEEPSC 962
I + SV Y C + +G C D+G WSG P C
Sbjct: 236 IQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPEC 283
Score = 95.9 bits (228), Expect = 7e-19
Identities = 68/249 (27%), Positives = 106/249 (42%), Gaps = 19/249 (7%)
Query: 471 CPDPPAVSNASVTVNGHKA---GSLASYTCENGHI-LSGST-SVTCTLGGAWSGVPPSCK 525
C PP V NA + G + ++ +Y CE + + G SV C G WS + C
Sbjct: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCN 95
Query: 526 YVNCGTPT-IHKGSFVLINGTTTY---GSIAQFTCEPDYWLNGA--EELVCNRDGKWSYD 579
+C PT ++ S T Y G++ ++ C P Y + +L C ++ KWS
Sbjct: 96 R-SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTA 154
Query: 580 IPSCELTSCPEP-EVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDG---EWS 635
+ C+ SCP P E+ +G +TI+F C G+KL G + C G +WS
Sbjct: 155 VEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWS 214
Query: 636 GDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCT---EEF 692
P C I C P + G ++ + Y+C + ++G CT +E
Sbjct: 215 DPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEG 274
Query: 693 QWSDSSPRC 701
+WS P C
Sbjct: 275 EWSGPPPEC 283
Score = 91.5 bits (217), Expect = 2e-17
Identities = 78/271 (28%), Positives = 111/271 (40%), Gaps = 35/271 (12%)
Query: 645 DCGKLPTLPYGTMELLNGTTHL--GSVIQYSCTTNYRLVGPVRRT--CTEEFQWSDSSPR 700
DCG P +P L G T +VI Y C ++ + + + C + QWSD
Sbjct: 35 DCGLPPDVP-NAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEF 93
Query: 701 CEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVI 760
C C P N S I N + +G +V+Y C GY+
Sbjct: 94 CNR-SCEVPTRL---------NSASLKQPYITQ-------NYFPVGTVVEYECRPGYRR- 135
Query: 761 GESLS---TCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENW 817
SLS TC N +WS C+ C NPG I NG++ +P F GAT + C+ +
Sbjct: 136 EPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILF-GATISFSCNTGY 194
Query: 818 ELEGVIRRMCQENGT---WSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQ 874
+L G C +G+ WS P C+EI CP P QI G + Y
Sbjct: 195 KLFGSTSSFCLISGSSVQWSDPLPECREIYCPAP-PQIDNGI-IQGERDHYGYRQSVTYA 252
Query: 875 CERGYNLKGHQTRTCI---SKGQWNGTVPVC 902
C +G+ + G + C +G+W+G P C
Sbjct: 253 CNKGFTMIGEHSIYCTVNNDEGEWSGPPPEC 283
Score = 85.4 bits (202), Expect = 1e-15
Identities = 70/271 (25%), Positives = 111/271 (40%), Gaps = 38/271 (14%)
Query: 528 NCGTPTIHKGSFVLINGTTTY--GSIAQFTCEPDYWLNGAEE--LVCNRDGKWSYDIPSC 583
+CG P + + G T++ ++ + CE + E+ ++C + +WS DI
Sbjct: 35 DCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWS-DIEEF 93
Query: 584 ELTSCPEP-EVPSGGYMEAF---DYY-VHSTINFHCEAGHKLIGE--PNLVCQQDGEWSG 636
SC P + S + + +Y+ V + + + C G++ P L C Q+ +WS
Sbjct: 94 CNRSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWST 153
Query: 637 DSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCT---EEFQ 693
C+ C + G +++ G G+ I +SC T Y+L G C Q
Sbjct: 154 AVEFCKKKSCPNPGEIRNGQIDVPGGIL-FGATISFSCNTGYKLFGSTSSFCLISGSSVQ 212
Query: 694 WSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRC 753
WSD P C EI C P + I+ +R H Y V Y C
Sbjct: 213 WSDPLPECREIYCPAPPQIDNGIIQ---GERDH----------------YGYRQSVTYAC 253
Query: 754 EKGYKVIGESLSTC---EDNGQWSGTTPTCQ 781
KG+ +IGE C D G+WSG P C+
Sbjct: 254 NKGFTMIGEHSIYCTVNNDEGEWSGPPPECR 284
Score = 85.4 bits (202), Expect = 1e-15
Identities = 64/248 (25%), Positives = 101/248 (40%), Gaps = 20/248 (8%)
Query: 413 GLTPIEDGDVALIDNRTTHGARAL--YSCRENFTLVGNPERT--CGDEGIWDGEAPRCLF 468
GL P ++ RT+ + Y C E+F + + + C W C
Sbjct: 37 GLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNR 96
Query: 469 DWCPDPPAVSNAS-----VTVNGHKAGSLASYTCENGHILSGSTS--VTCTLGGAWSGVP 521
C P +++AS +T N G++ Y C G+ S S +TC WS
Sbjct: 97 S-CEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAV 155
Query: 522 PSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDG---KWSY 578
CK +C P + + + G +G+ F+C Y L G+ C G +WS
Sbjct: 156 EFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSD 215
Query: 579 DIPSCELTSCP-EPEVPSGGYMEAFDYY-VHSTINFHCEAGHKLIGEPNLVC---QQDGE 633
+P C CP P++ +G D+Y ++ + C G +IGE ++ C +GE
Sbjct: 216 PLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGE 275
Query: 634 WSGDSPTC 641
WSG P C
Sbjct: 276 WSGPPPEC 283
Score = 78.6 bits (185), Expect = 1e-13
Identities = 65/242 (26%), Positives = 97/242 (40%), Gaps = 21/242 (8%)
Query: 317 GEQNCVVLDGGRGWLWNDVGCNLDYLHWICQYLPPTCGSPDKLLNTTILGNDYDVGSRIV 376
GE++ V+ G W + CN C+ PT + L I N + VG+ +
Sbjct: 74 GEKDSVICLKGSQWSDIEEFCNRS-----CEV--PTRLNSASLKQPYITQNYFPVGTVVE 126
Query: 377 YKCPEGHMLLGDKSRH--CKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRTTHGAR 434
Y+C G+ S C ++ WS A CK +C I +G + + GA
Sbjct: 127 YECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQID-VPGGILFGAT 185
Query: 435 ALYSCRENFTLVGNPERTC---GDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGS 491
+SC + L G+ C G W P C +CP PP + N + G
Sbjct: 186 ISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGY 245
Query: 492 LAS--YTCENGHILSGSTSVTCTLG---GAWSGVPPSCKYVNCGT---PTIHKGSFVLIN 543
S Y C G + G S+ CT+ G WSG PP C+ + + PT+ K + V +
Sbjct: 246 RQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTVQKPTTVNVP 305
Query: 544 GT 545
T
Sbjct: 306 TT 307
Score = 74.9 bits (176), Expect = 1e-12
Identities = 66/267 (24%), Positives = 113/267 (42%), Gaps = 38/267 (14%)
Query: 591 PEVPSGG-YMEAFDYYVHST-INFHCEAGH-KLIGEPN-LVCQQDGEWSGDSPTCEYIDC 646
P+VP+ +E + T I + CE K+ GE + ++C + +WS C C
Sbjct: 40 PDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNR-SC 98
Query: 647 GKLPT-LPYGTME---LLNGTTHLGSVIQYSCTTNYRLVGPV--RRTCTEEFQWSDSSPR 700
++PT L +++ + +G+V++Y C YR + + TC + +WS +
Sbjct: 99 -EVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEF 157
Query: 701 CEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVI 760
C++ C +P + V G GA + + C GYK+
Sbjct: 158 CKKKSCPNPGEIRNGQIDVPGG--------------------ILFGATISFSCNTGYKLF 197
Query: 761 GESLSTCEDNG---QWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENW 817
G + S C +G QWS P C+ + C P +I+NG + + Y + Y C++ +
Sbjct: 198 GSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGF 257
Query: 818 ELEGVIRRMCQEN---GTWSLEPPICK 841
+ G C N G WS PP C+
Sbjct: 258 TMIGEHSIYCTVNNDEGEWSGPPPECR 284
Score = 73.3 bits (172), Expect = 4e-12
Identities = 53/191 (27%), Positives = 82/191 (42%), Gaps = 17/191 (8%)
Query: 784 DCGNPGRIENGKVTLPSNATFYGATAF-YQCDENW-----ELEGVIRRMCQENGTWSLEP 837
DCG P + N + L +F T Y+C+E++ E + VI C + WS
Sbjct: 35 DCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVI---CLKGSQWSDIE 91
Query: 838 PICKEITCPDPSAQIKAGSGLLVVTST-LSIGGEAHYQCERGYNLKGHQTR--TCISKGQ 894
C +C P+ A +T +G Y+C GY + + TC+ +
Sbjct: 92 EFCNR-SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLK 150
Query: 895 WNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDG- 953
W+ V C C +PG I NG+I + G LFG+++ + C + Y+ G CL G
Sbjct: 151 WSTAVEFCKKKSCPNPGEIRNGQIDVP-GGILFGATISFSCNTGYKLFGSTSSFCLISGS 209
Query: 954 --RWSGEEPSC 962
+WS P C
Sbjct: 210 SVQWSDPLPEC 220
Score = 34.3 bits (75), Expect = 2.4
Identities = 17/60 (28%), Positives = 28/60 (46%), Gaps = 5/60 (8%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRG---DWTLEPPFC 58
C +P N ++ +P I+ G + C+ GY+LFG+ C + G W+ P C
Sbjct: 163 CPNPGEIRNGQIDVPG--GILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPEC 220
Score = 32.3 bits (70), Expect = 9.7
Identities = 16/59 (27%), Positives = 29/59 (49%), Gaps = 2/59 (3%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGY-ELFGARQRECTLRG-DWTLEPPFC 58
CG P PNA+ ++ + T+ Y+C+E + ++ G + L+G W+ FC
Sbjct: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFC 94
>AY851161-1|AAW29942.1| 381|Homo sapiens decay accelerating factor
for complement (CD55, Cromer blood group system)
protein.
Length = 381
Score = 97.5 bits (232), Expect = 2e-19
Identities = 65/228 (28%), Positives = 98/228 (42%), Gaps = 17/228 (7%)
Query: 748 LVKYRCEKGY-KVIGESLST-CEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFY 805
++ Y+CE+ + K+ GE S C QWS C C P R+ + + P Y
Sbjct: 60 VITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNR-SCEVPTRLNSASLKQPYITQNY 118
Query: 806 ---GATAFYQCDENWELEGVI--RRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLV 860
G Y+C + E + + C +N WS CK+ +CP+P +I+ +G +
Sbjct: 119 FPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPG-EIR--NGQID 175
Query: 861 VTSTLSIGGEAHYQCERGYNLKGHQTRTCISKG---QWNGTVPVCIPIDCRSPGNIENGK 917
V + G + C GY L G + C+ G QW+ +P C I C +P I+NG
Sbjct: 176 VPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGI 235
Query: 918 IVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCL---DDGRWSGEEPSC 962
I + SV Y C + +G C D+G WSG P C
Sbjct: 236 IQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPEC 283
Score = 95.9 bits (228), Expect = 7e-19
Identities = 68/249 (27%), Positives = 106/249 (42%), Gaps = 19/249 (7%)
Query: 471 CPDPPAVSNASVTVNGHKA---GSLASYTCENGHI-LSGST-SVTCTLGGAWSGVPPSCK 525
C PP V NA + G + ++ +Y CE + + G SV C G WS + C
Sbjct: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCN 95
Query: 526 YVNCGTPT-IHKGSFVLINGTTTY---GSIAQFTCEPDYWLNGA--EELVCNRDGKWSYD 579
+C PT ++ S T Y G++ ++ C P Y + +L C ++ KWS
Sbjct: 96 R-SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTA 154
Query: 580 IPSCELTSCPEP-EVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDG---EWS 635
+ C+ SCP P E+ +G +TI+F C G+KL G + C G +WS
Sbjct: 155 VEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWS 214
Query: 636 GDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCT---EEF 692
P C I C P + G ++ + Y+C + ++G CT +E
Sbjct: 215 DPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEG 274
Query: 693 QWSDSSPRC 701
+WS P C
Sbjct: 275 EWSGPPPEC 283
Score = 91.5 bits (217), Expect = 2e-17
Identities = 78/271 (28%), Positives = 111/271 (40%), Gaps = 35/271 (12%)
Query: 645 DCGKLPTLPYGTMELLNGTTHL--GSVIQYSCTTNYRLVGPVRRT--CTEEFQWSDSSPR 700
DCG P +P L G T +VI Y C ++ + + + C + QWSD
Sbjct: 35 DCGLPPDVP-NAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEF 93
Query: 701 CEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVI 760
C C P N S I N + +G +V+Y C GY+
Sbjct: 94 CNR-SCEVPTRL---------NSASLKQPYITQ-------NYFPVGTVVEYECRPGYRR- 135
Query: 761 GESLS---TCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENW 817
SLS TC N +WS C+ C NPG I NG++ +P F GAT + C+ +
Sbjct: 136 EPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILF-GATISFSCNTGY 194
Query: 818 ELEGVIRRMCQENGT---WSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQ 874
+L G C +G+ WS P C+EI CP P QI G + Y
Sbjct: 195 KLFGSTSSFCLISGSSVQWSDPLPECREIYCPAP-PQIDNGI-IQGERDHYGYRQSVTYA 252
Query: 875 CERGYNLKGHQTRTCI---SKGQWNGTVPVC 902
C +G+ + G + C +G+W+G P C
Sbjct: 253 CNKGFTMIGEHSIYCTVNNDEGEWSGPPPEC 283
Score = 85.4 bits (202), Expect = 1e-15
Identities = 70/271 (25%), Positives = 111/271 (40%), Gaps = 38/271 (14%)
Query: 528 NCGTPTIHKGSFVLINGTTTY--GSIAQFTCEPDYWLNGAEE--LVCNRDGKWSYDIPSC 583
+CG P + + G T++ ++ + CE + E+ ++C + +WS DI
Sbjct: 35 DCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWS-DIEEF 93
Query: 584 ELTSCPEP-EVPSGGYMEAF---DYY-VHSTINFHCEAGHKLIGE--PNLVCQQDGEWSG 636
SC P + S + + +Y+ V + + + C G++ P L C Q+ +WS
Sbjct: 94 CNRSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWST 153
Query: 637 DSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCT---EEFQ 693
C+ C + G +++ G G+ I +SC T Y+L G C Q
Sbjct: 154 AVEFCKKKSCPNPGEIRNGQIDVPGGIL-FGATISFSCNTGYKLFGSTSSFCLISGSSVQ 212
Query: 694 WSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRC 753
WSD P C EI C P + I+ +R H Y V Y C
Sbjct: 213 WSDPLPECREIYCPAPPQIDNGIIQ---GERDH----------------YGYRQSVTYAC 253
Query: 754 EKGYKVIGESLSTC---EDNGQWSGTTPTCQ 781
KG+ +IGE C D G+WSG P C+
Sbjct: 254 NKGFTMIGEHSIYCTVNNDEGEWSGPPPECR 284
Score = 85.4 bits (202), Expect = 1e-15
Identities = 64/248 (25%), Positives = 101/248 (40%), Gaps = 20/248 (8%)
Query: 413 GLTPIEDGDVALIDNRTTHGARAL--YSCRENFTLVGNPERT--CGDEGIWDGEAPRCLF 468
GL P ++ RT+ + Y C E+F + + + C W C
Sbjct: 37 GLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNR 96
Query: 469 DWCPDPPAVSNAS-----VTVNGHKAGSLASYTCENGHILSGSTS--VTCTLGGAWSGVP 521
C P +++AS +T N G++ Y C G+ S S +TC WS
Sbjct: 97 S-CEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAV 155
Query: 522 PSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDG---KWSY 578
CK +C P + + + G +G+ F+C Y L G+ C G +WS
Sbjct: 156 EFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSD 215
Query: 579 DIPSCELTSCP-EPEVPSGGYMEAFDYY-VHSTINFHCEAGHKLIGEPNLVC---QQDGE 633
+P C CP P++ +G D+Y ++ + C G +IGE ++ C +GE
Sbjct: 216 PLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGE 275
Query: 634 WSGDSPTC 641
WSG P C
Sbjct: 276 WSGPPPEC 283
Score = 78.6 bits (185), Expect = 1e-13
Identities = 65/242 (26%), Positives = 97/242 (40%), Gaps = 21/242 (8%)
Query: 317 GEQNCVVLDGGRGWLWNDVGCNLDYLHWICQYLPPTCGSPDKLLNTTILGNDYDVGSRIV 376
GE++ V+ G W + CN C+ PT + L I N + VG+ +
Sbjct: 74 GEKDSVICLKGSQWSDIEEFCNRS-----CEV--PTRLNSASLKQPYITQNYFPVGTVVE 126
Query: 377 YKCPEGHMLLGDKSRH--CKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRTTHGAR 434
Y+C G+ S C ++ WS A CK +C I +G + + GA
Sbjct: 127 YECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQID-VPGGILFGAT 185
Query: 435 ALYSCRENFTLVGNPERTC---GDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGS 491
+SC + L G+ C G W P C +CP PP + N + G
Sbjct: 186 ISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGY 245
Query: 492 LAS--YTCENGHILSGSTSVTCTLG---GAWSGVPPSCKYVNCGT---PTIHKGSFVLIN 543
S Y C G + G S+ CT+ G WSG PP C+ + + PT+ K + V +
Sbjct: 246 RQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTVQKPTTVNVP 305
Query: 544 GT 545
T
Sbjct: 306 TT 307
Score = 74.9 bits (176), Expect = 1e-12
Identities = 66/267 (24%), Positives = 113/267 (42%), Gaps = 38/267 (14%)
Query: 591 PEVPSGG-YMEAFDYYVHST-INFHCEAGH-KLIGEPN-LVCQQDGEWSGDSPTCEYIDC 646
P+VP+ +E + T I + CE K+ GE + ++C + +WS C C
Sbjct: 40 PDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNR-SC 98
Query: 647 GKLPT-LPYGTME---LLNGTTHLGSVIQYSCTTNYRLVGPV--RRTCTEEFQWSDSSPR 700
++PT L +++ + +G+V++Y C YR + + TC + +WS +
Sbjct: 99 -EVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEF 157
Query: 701 CEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVI 760
C++ C +P + V G GA + + C GYK+
Sbjct: 158 CKKKSCPNPGEIRNGQIDVPGG--------------------ILFGATISFSCNTGYKLF 197
Query: 761 GESLSTCEDNG---QWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENW 817
G + S C +G QWS P C+ + C P +I+NG + + Y + Y C++ +
Sbjct: 198 GSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGF 257
Query: 818 ELEGVIRRMCQEN---GTWSLEPPICK 841
+ G C N G WS PP C+
Sbjct: 258 TMIGEHSIYCTVNNDEGEWSGPPPECR 284
Score = 73.3 bits (172), Expect = 4e-12
Identities = 53/191 (27%), Positives = 82/191 (42%), Gaps = 17/191 (8%)
Query: 784 DCGNPGRIENGKVTLPSNATFYGATAF-YQCDENW-----ELEGVIRRMCQENGTWSLEP 837
DCG P + N + L +F T Y+C+E++ E + VI C + WS
Sbjct: 35 DCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVI---CLKGSQWSDIE 91
Query: 838 PICKEITCPDPSAQIKAGSGLLVVTST-LSIGGEAHYQCERGYNLKGHQTR--TCISKGQ 894
C +C P+ A +T +G Y+C GY + + TC+ +
Sbjct: 92 EFCNR-SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLK 150
Query: 895 WNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDG- 953
W+ V C C +PG I NG+I + G LFG+++ + C + Y+ G CL G
Sbjct: 151 WSTAVEFCKKKSCPNPGEIRNGQIDVP-GGILFGATISFSCNTGYKLFGSTSSFCLISGS 209
Query: 954 --RWSGEEPSC 962
+WS P C
Sbjct: 210 SVQWSDPLPEC 220
Score = 34.3 bits (75), Expect = 2.4
Identities = 17/60 (28%), Positives = 28/60 (46%), Gaps = 5/60 (8%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRG---DWTLEPPFC 58
C +P N ++ +P I+ G + C+ GY+LFG+ C + G W+ P C
Sbjct: 163 CPNPGEIRNGQIDVPG--GILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPEC 220
Score = 32.3 bits (70), Expect = 9.7
Identities = 16/59 (27%), Positives = 29/59 (49%), Gaps = 2/59 (3%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGY-ELFGARQRECTLRG-DWTLEPPFC 58
CG P PNA+ ++ + T+ Y+C+E + ++ G + L+G W+ FC
Sbjct: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFC 94
>AL596218-5|CAI16464.1| 293|Homo sapiens CD55 molecule, decay
accelerating factor for complement (Cromer blood group)
protein.
Length = 293
Score = 97.5 bits (232), Expect = 2e-19
Identities = 65/228 (28%), Positives = 98/228 (42%), Gaps = 17/228 (7%)
Query: 748 LVKYRCEKGY-KVIGESLST-CEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFY 805
++ Y+CE+ + K+ GE S C QWS C C P R+ + + P Y
Sbjct: 37 VITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNR-SCEVPTRLNSASLKQPYITQNY 95
Query: 806 ---GATAFYQCDENWELEGVI--RRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLV 860
G Y+C + E + + C +N WS CK+ +CP+P +I+ +G +
Sbjct: 96 FPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPG-EIR--NGQID 152
Query: 861 VTSTLSIGGEAHYQCERGYNLKGHQTRTCISKG---QWNGTVPVCIPIDCRSPGNIENGK 917
V + G + C GY L G + C+ G QW+ +P C I C +P I+NG
Sbjct: 153 VPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGI 212
Query: 918 IVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCL---DDGRWSGEEPSC 962
I + SV Y C + +G C D+G WSG P C
Sbjct: 213 IQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPEC 260
Score = 95.9 bits (228), Expect = 7e-19
Identities = 68/249 (27%), Positives = 106/249 (42%), Gaps = 19/249 (7%)
Query: 471 CPDPPAVSNASVTVNGHKA---GSLASYTCENGHI-LSGST-SVTCTLGGAWSGVPPSCK 525
C PP V NA + G + ++ +Y CE + + G SV C G WS + C
Sbjct: 13 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCN 72
Query: 526 YVNCGTPT-IHKGSFVLINGTTTY---GSIAQFTCEPDYWLNGA--EELVCNRDGKWSYD 579
+C PT ++ S T Y G++ ++ C P Y + +L C ++ KWS
Sbjct: 73 R-SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTA 131
Query: 580 IPSCELTSCPEP-EVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDG---EWS 635
+ C+ SCP P E+ +G +TI+F C G+KL G + C G +WS
Sbjct: 132 VEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWS 191
Query: 636 GDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCT---EEF 692
P C I C P + G ++ + Y+C + ++G CT +E
Sbjct: 192 DPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEG 251
Query: 693 QWSDSSPRC 701
+WS P C
Sbjct: 252 EWSGPPPEC 260
Score = 91.5 bits (217), Expect = 2e-17
Identities = 78/271 (28%), Positives = 111/271 (40%), Gaps = 35/271 (12%)
Query: 645 DCGKLPTLPYGTMELLNGTTHL--GSVIQYSCTTNYRLVGPVRRT--CTEEFQWSDSSPR 700
DCG P +P L G T +VI Y C ++ + + + C + QWSD
Sbjct: 12 DCGLPPDVP-NAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEF 70
Query: 701 CEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVI 760
C C P N S I N + +G +V+Y C GY+
Sbjct: 71 CNR-SCEVPTRL---------NSASLKQPYITQ-------NYFPVGTVVEYECRPGYRR- 112
Query: 761 GESLS---TCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENW 817
SLS TC N +WS C+ C NPG I NG++ +P F GAT + C+ +
Sbjct: 113 EPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILF-GATISFSCNTGY 171
Query: 818 ELEGVIRRMCQENGT---WSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQ 874
+L G C +G+ WS P C+EI CP P QI G + Y
Sbjct: 172 KLFGSTSSFCLISGSSVQWSDPLPECREIYCPAP-PQIDNGI-IQGERDHYGYRQSVTYA 229
Query: 875 CERGYNLKGHQTRTCI---SKGQWNGTVPVC 902
C +G+ + G + C +G+W+G P C
Sbjct: 230 CNKGFTMIGEHSIYCTVNNDEGEWSGPPPEC 260
Score = 85.4 bits (202), Expect = 1e-15
Identities = 70/271 (25%), Positives = 111/271 (40%), Gaps = 38/271 (14%)
Query: 528 NCGTPTIHKGSFVLINGTTTY--GSIAQFTCEPDYWLNGAEE--LVCNRDGKWSYDIPSC 583
+CG P + + G T++ ++ + CE + E+ ++C + +WS DI
Sbjct: 12 DCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWS-DIEEF 70
Query: 584 ELTSCPEP-EVPSGGYMEAF---DYY-VHSTINFHCEAGHKLIGE--PNLVCQQDGEWSG 636
SC P + S + + +Y+ V + + + C G++ P L C Q+ +WS
Sbjct: 71 CNRSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWST 130
Query: 637 DSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCT---EEFQ 693
C+ C + G +++ G G+ I +SC T Y+L G C Q
Sbjct: 131 AVEFCKKKSCPNPGEIRNGQIDVPGGIL-FGATISFSCNTGYKLFGSTSSFCLISGSSVQ 189
Query: 694 WSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRC 753
WSD P C EI C P + I+ +R H Y V Y C
Sbjct: 190 WSDPLPECREIYCPAPPQIDNGIIQ---GERDH----------------YGYRQSVTYAC 230
Query: 754 EKGYKVIGESLSTC---EDNGQWSGTTPTCQ 781
KG+ +IGE C D G+WSG P C+
Sbjct: 231 NKGFTMIGEHSIYCTVNNDEGEWSGPPPECR 261
Score = 85.4 bits (202), Expect = 1e-15
Identities = 64/248 (25%), Positives = 101/248 (40%), Gaps = 20/248 (8%)
Query: 413 GLTPIEDGDVALIDNRTTHGARAL--YSCRENFTLVGNPERT--CGDEGIWDGEAPRCLF 468
GL P ++ RT+ + Y C E+F + + + C W C
Sbjct: 14 GLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNR 73
Query: 469 DWCPDPPAVSNAS-----VTVNGHKAGSLASYTCENGHILSGSTS--VTCTLGGAWSGVP 521
C P +++AS +T N G++ Y C G+ S S +TC WS
Sbjct: 74 S-CEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAV 132
Query: 522 PSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDG---KWSY 578
CK +C P + + + G +G+ F+C Y L G+ C G +WS
Sbjct: 133 EFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSD 192
Query: 579 DIPSCELTSCP-EPEVPSGGYMEAFDYY-VHSTINFHCEAGHKLIGEPNLVC---QQDGE 633
+P C CP P++ +G D+Y ++ + C G +IGE ++ C +GE
Sbjct: 193 PLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGE 252
Query: 634 WSGDSPTC 641
WSG P C
Sbjct: 253 WSGPPPEC 260
Score = 78.6 bits (185), Expect = 1e-13
Identities = 65/242 (26%), Positives = 97/242 (40%), Gaps = 21/242 (8%)
Query: 317 GEQNCVVLDGGRGWLWNDVGCNLDYLHWICQYLPPTCGSPDKLLNTTILGNDYDVGSRIV 376
GE++ V+ G W + CN C+ PT + L I N + VG+ +
Sbjct: 51 GEKDSVICLKGSQWSDIEEFCNRS-----CEV--PTRLNSASLKQPYITQNYFPVGTVVE 103
Query: 377 YKCPEGHMLLGDKSRH--CKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRTTHGAR 434
Y+C G+ S C ++ WS A CK +C I +G + + GA
Sbjct: 104 YECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQID-VPGGILFGAT 162
Query: 435 ALYSCRENFTLVGNPERTC---GDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGS 491
+SC + L G+ C G W P C +CP PP + N + G
Sbjct: 163 ISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGY 222
Query: 492 LAS--YTCENGHILSGSTSVTCTLG---GAWSGVPPSCKYVNCGT---PTIHKGSFVLIN 543
S Y C G + G S+ CT+ G WSG PP C+ + + PT+ K + V +
Sbjct: 223 RQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTVQKPTTVNVP 282
Query: 544 GT 545
T
Sbjct: 283 TT 284
Score = 74.9 bits (176), Expect = 1e-12
Identities = 66/267 (24%), Positives = 113/267 (42%), Gaps = 38/267 (14%)
Query: 591 PEVPSGG-YMEAFDYYVHST-INFHCEAGH-KLIGEPN-LVCQQDGEWSGDSPTCEYIDC 646
P+VP+ +E + T I + CE K+ GE + ++C + +WS C C
Sbjct: 17 PDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNR-SC 75
Query: 647 GKLPT-LPYGTME---LLNGTTHLGSVIQYSCTTNYRLVGPV--RRTCTEEFQWSDSSPR 700
++PT L +++ + +G+V++Y C YR + + TC + +WS +
Sbjct: 76 -EVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEF 134
Query: 701 CEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVI 760
C++ C +P + V G GA + + C GYK+
Sbjct: 135 CKKKSCPNPGEIRNGQIDVPGG--------------------ILFGATISFSCNTGYKLF 174
Query: 761 GESLSTCEDNG---QWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENW 817
G + S C +G QWS P C+ + C P +I+NG + + Y + Y C++ +
Sbjct: 175 GSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGF 234
Query: 818 ELEGVIRRMCQEN---GTWSLEPPICK 841
+ G C N G WS PP C+
Sbjct: 235 TMIGEHSIYCTVNNDEGEWSGPPPECR 261
Score = 73.3 bits (172), Expect = 4e-12
Identities = 53/191 (27%), Positives = 82/191 (42%), Gaps = 17/191 (8%)
Query: 784 DCGNPGRIENGKVTLPSNATFYGATAF-YQCDENW-----ELEGVIRRMCQENGTWSLEP 837
DCG P + N + L +F T Y+C+E++ E + VI C + WS
Sbjct: 12 DCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVI---CLKGSQWSDIE 68
Query: 838 PICKEITCPDPSAQIKAGSGLLVVTST-LSIGGEAHYQCERGYNLKGHQTR--TCISKGQ 894
C +C P+ A +T +G Y+C GY + + TC+ +
Sbjct: 69 EFCNR-SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLK 127
Query: 895 WNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDG- 953
W+ V C C +PG I NG+I + G LFG+++ + C + Y+ G CL G
Sbjct: 128 WSTAVEFCKKKSCPNPGEIRNGQIDVP-GGILFGATISFSCNTGYKLFGSTSSFCLISGS 186
Query: 954 --RWSGEEPSC 962
+WS P C
Sbjct: 187 SVQWSDPLPEC 197
Score = 34.3 bits (75), Expect = 2.4
Identities = 17/60 (28%), Positives = 28/60 (46%), Gaps = 5/60 (8%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRG---DWTLEPPFC 58
C +P N ++ +P I+ G + C+ GY+LFG+ C + G W+ P C
Sbjct: 140 CPNPGEIRNGQIDVPG--GILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPEC 197
Score = 32.3 bits (70), Expect = 9.7
Identities = 16/59 (27%), Positives = 29/59 (49%), Gaps = 2/59 (3%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGY-ELFGARQRECTLRG-DWTLEPPFC 58
CG P PNA+ ++ + T+ Y+C+E + ++ G + L+G W+ FC
Sbjct: 13 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFC 71
>AL596218-4|CAI16463.1| 381|Homo sapiens CD55 molecule, decay
accelerating factor for complement (Cromer blood group)
protein.
Length = 381
Score = 97.5 bits (232), Expect = 2e-19
Identities = 65/228 (28%), Positives = 98/228 (42%), Gaps = 17/228 (7%)
Query: 748 LVKYRCEKGY-KVIGESLST-CEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFY 805
++ Y+CE+ + K+ GE S C QWS C C P R+ + + P Y
Sbjct: 60 VITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNR-SCEVPTRLNSASLKQPYITQNY 118
Query: 806 ---GATAFYQCDENWELEGVI--RRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLV 860
G Y+C + E + + C +N WS CK+ +CP+P +I+ +G +
Sbjct: 119 FPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPG-EIR--NGQID 175
Query: 861 VTSTLSIGGEAHYQCERGYNLKGHQTRTCISKG---QWNGTVPVCIPIDCRSPGNIENGK 917
V + G + C GY L G + C+ G QW+ +P C I C +P I+NG
Sbjct: 176 VPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGI 235
Query: 918 IVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCL---DDGRWSGEEPSC 962
I + SV Y C + +G C D+G WSG P C
Sbjct: 236 IQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPEC 283
Score = 95.9 bits (228), Expect = 7e-19
Identities = 68/249 (27%), Positives = 106/249 (42%), Gaps = 19/249 (7%)
Query: 471 CPDPPAVSNASVTVNGHKA---GSLASYTCENGHI-LSGST-SVTCTLGGAWSGVPPSCK 525
C PP V NA + G + ++ +Y CE + + G SV C G WS + C
Sbjct: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCN 95
Query: 526 YVNCGTPT-IHKGSFVLINGTTTY---GSIAQFTCEPDYWLNGA--EELVCNRDGKWSYD 579
+C PT ++ S T Y G++ ++ C P Y + +L C ++ KWS
Sbjct: 96 R-SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTA 154
Query: 580 IPSCELTSCPEP-EVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDG---EWS 635
+ C+ SCP P E+ +G +TI+F C G+KL G + C G +WS
Sbjct: 155 VEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWS 214
Query: 636 GDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCT---EEF 692
P C I C P + G ++ + Y+C + ++G CT +E
Sbjct: 215 DPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEG 274
Query: 693 QWSDSSPRC 701
+WS P C
Sbjct: 275 EWSGPPPEC 283
Score = 91.5 bits (217), Expect = 2e-17
Identities = 78/271 (28%), Positives = 111/271 (40%), Gaps = 35/271 (12%)
Query: 645 DCGKLPTLPYGTMELLNGTTHL--GSVIQYSCTTNYRLVGPVRRT--CTEEFQWSDSSPR 700
DCG P +P L G T +VI Y C ++ + + + C + QWSD
Sbjct: 35 DCGLPPDVP-NAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEF 93
Query: 701 CEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVI 760
C C P N S I N + +G +V+Y C GY+
Sbjct: 94 CNR-SCEVPTRL---------NSASLKQPYITQ-------NYFPVGTVVEYECRPGYRR- 135
Query: 761 GESLS---TCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENW 817
SLS TC N +WS C+ C NPG I NG++ +P F GAT + C+ +
Sbjct: 136 EPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILF-GATISFSCNTGY 194
Query: 818 ELEGVIRRMCQENGT---WSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQ 874
+L G C +G+ WS P C+EI CP P QI G + Y
Sbjct: 195 KLFGSTSSFCLISGSSVQWSDPLPECREIYCPAP-PQIDNGI-IQGERDHYGYRQSVTYA 252
Query: 875 CERGYNLKGHQTRTCI---SKGQWNGTVPVC 902
C +G+ + G + C +G+W+G P C
Sbjct: 253 CNKGFTMIGEHSIYCTVNNDEGEWSGPPPEC 283
Score = 85.4 bits (202), Expect = 1e-15
Identities = 70/271 (25%), Positives = 111/271 (40%), Gaps = 38/271 (14%)
Query: 528 NCGTPTIHKGSFVLINGTTTY--GSIAQFTCEPDYWLNGAEE--LVCNRDGKWSYDIPSC 583
+CG P + + G T++ ++ + CE + E+ ++C + +WS DI
Sbjct: 35 DCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWS-DIEEF 93
Query: 584 ELTSCPEP-EVPSGGYMEAF---DYY-VHSTINFHCEAGHKLIGE--PNLVCQQDGEWSG 636
SC P + S + + +Y+ V + + + C G++ P L C Q+ +WS
Sbjct: 94 CNRSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWST 153
Query: 637 DSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCT---EEFQ 693
C+ C + G +++ G G+ I +SC T Y+L G C Q
Sbjct: 154 AVEFCKKKSCPNPGEIRNGQIDVPGGIL-FGATISFSCNTGYKLFGSTSSFCLISGSSVQ 212
Query: 694 WSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRC 753
WSD P C EI C P + I+ +R H Y V Y C
Sbjct: 213 WSDPLPECREIYCPAPPQIDNGIIQ---GERDH----------------YGYRQSVTYAC 253
Query: 754 EKGYKVIGESLSTC---EDNGQWSGTTPTCQ 781
KG+ +IGE C D G+WSG P C+
Sbjct: 254 NKGFTMIGEHSIYCTVNNDEGEWSGPPPECR 284
Score = 85.4 bits (202), Expect = 1e-15
Identities = 64/248 (25%), Positives = 101/248 (40%), Gaps = 20/248 (8%)
Query: 413 GLTPIEDGDVALIDNRTTHGARAL--YSCRENFTLVGNPERT--CGDEGIWDGEAPRCLF 468
GL P ++ RT+ + Y C E+F + + + C W C
Sbjct: 37 GLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNR 96
Query: 469 DWCPDPPAVSNAS-----VTVNGHKAGSLASYTCENGHILSGSTS--VTCTLGGAWSGVP 521
C P +++AS +T N G++ Y C G+ S S +TC WS
Sbjct: 97 S-CEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAV 155
Query: 522 PSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDG---KWSY 578
CK +C P + + + G +G+ F+C Y L G+ C G +WS
Sbjct: 156 EFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSD 215
Query: 579 DIPSCELTSCP-EPEVPSGGYMEAFDYY-VHSTINFHCEAGHKLIGEPNLVC---QQDGE 633
+P C CP P++ +G D+Y ++ + C G +IGE ++ C +GE
Sbjct: 216 PLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGE 275
Query: 634 WSGDSPTC 641
WSG P C
Sbjct: 276 WSGPPPEC 283
Score = 78.6 bits (185), Expect = 1e-13
Identities = 65/242 (26%), Positives = 97/242 (40%), Gaps = 21/242 (8%)
Query: 317 GEQNCVVLDGGRGWLWNDVGCNLDYLHWICQYLPPTCGSPDKLLNTTILGNDYDVGSRIV 376
GE++ V+ G W + CN C+ PT + L I N + VG+ +
Sbjct: 74 GEKDSVICLKGSQWSDIEEFCNRS-----CEV--PTRLNSASLKQPYITQNYFPVGTVVE 126
Query: 377 YKCPEGHMLLGDKSRH--CKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRTTHGAR 434
Y+C G+ S C ++ WS A CK +C I +G + + GA
Sbjct: 127 YECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQID-VPGGILFGAT 185
Query: 435 ALYSCRENFTLVGNPERTC---GDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGS 491
+SC + L G+ C G W P C +CP PP + N + G
Sbjct: 186 ISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGY 245
Query: 492 LAS--YTCENGHILSGSTSVTCTLG---GAWSGVPPSCKYVNCGT---PTIHKGSFVLIN 543
S Y C G + G S+ CT+ G WSG PP C+ + + PT+ K + V +
Sbjct: 246 RQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTVQKPTTVNVP 305
Query: 544 GT 545
T
Sbjct: 306 TT 307
Score = 74.9 bits (176), Expect = 1e-12
Identities = 66/267 (24%), Positives = 113/267 (42%), Gaps = 38/267 (14%)
Query: 591 PEVPSGG-YMEAFDYYVHST-INFHCEAGH-KLIGEPN-LVCQQDGEWSGDSPTCEYIDC 646
P+VP+ +E + T I + CE K+ GE + ++C + +WS C C
Sbjct: 40 PDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNR-SC 98
Query: 647 GKLPT-LPYGTME---LLNGTTHLGSVIQYSCTTNYRLVGPV--RRTCTEEFQWSDSSPR 700
++PT L +++ + +G+V++Y C YR + + TC + +WS +
Sbjct: 99 -EVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEF 157
Query: 701 CEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVI 760
C++ C +P + V G GA + + C GYK+
Sbjct: 158 CKKKSCPNPGEIRNGQIDVPGG--------------------ILFGATISFSCNTGYKLF 197
Query: 761 GESLSTCEDNG---QWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENW 817
G + S C +G QWS P C+ + C P +I+NG + + Y + Y C++ +
Sbjct: 198 GSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGF 257
Query: 818 ELEGVIRRMCQEN---GTWSLEPPICK 841
+ G C N G WS PP C+
Sbjct: 258 TMIGEHSIYCTVNNDEGEWSGPPPECR 284
Score = 73.3 bits (172), Expect = 4e-12
Identities = 53/191 (27%), Positives = 82/191 (42%), Gaps = 17/191 (8%)
Query: 784 DCGNPGRIENGKVTLPSNATFYGATAF-YQCDENW-----ELEGVIRRMCQENGTWSLEP 837
DCG P + N + L +F T Y+C+E++ E + VI C + WS
Sbjct: 35 DCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVI---CLKGSQWSDIE 91
Query: 838 PICKEITCPDPSAQIKAGSGLLVVTST-LSIGGEAHYQCERGYNLKGHQTR--TCISKGQ 894
C +C P+ A +T +G Y+C GY + + TC+ +
Sbjct: 92 EFCNR-SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLK 150
Query: 895 WNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDG- 953
W+ V C C +PG I NG+I + G LFG+++ + C + Y+ G CL G
Sbjct: 151 WSTAVEFCKKKSCPNPGEIRNGQIDVP-GGILFGATISFSCNTGYKLFGSTSSFCLISGS 209
Query: 954 --RWSGEEPSC 962
+WS P C
Sbjct: 210 SVQWSDPLPEC 220
Score = 34.3 bits (75), Expect = 2.4
Identities = 17/60 (28%), Positives = 28/60 (46%), Gaps = 5/60 (8%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRG---DWTLEPPFC 58
C +P N ++ +P I+ G + C+ GY+LFG+ C + G W+ P C
Sbjct: 163 CPNPGEIRNGQIDVPG--GILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPEC 220
Score = 32.3 bits (70), Expect = 9.7
Identities = 16/59 (27%), Positives = 29/59 (49%), Gaps = 2/59 (3%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGY-ELFGARQRECTLRG-DWTLEPPFC 58
CG P PNA+ ++ + T+ Y+C+E + ++ G + L+G W+ FC
Sbjct: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFC 94
>AL596218-2|CAI16461.1| 444|Homo sapiens CD55 molecule, decay
accelerating factor for complement (Cromer blood group)
protein.
Length = 444
Score = 97.5 bits (232), Expect = 2e-19
Identities = 65/228 (28%), Positives = 98/228 (42%), Gaps = 17/228 (7%)
Query: 748 LVKYRCEKGY-KVIGESLST-CEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFY 805
++ Y+CE+ + K+ GE S C QWS C C P R+ + + P Y
Sbjct: 60 VITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNR-SCEVPTRLNSASLKQPYITQNY 118
Query: 806 ---GATAFYQCDENWELEGVI--RRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLV 860
G Y+C + E + + C +N WS CK+ +CP+P +I+ +G +
Sbjct: 119 FPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPG-EIR--NGQID 175
Query: 861 VTSTLSIGGEAHYQCERGYNLKGHQTRTCISKG---QWNGTVPVCIPIDCRSPGNIENGK 917
V + G + C GY L G + C+ G QW+ +P C I C +P I+NG
Sbjct: 176 VPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGI 235
Query: 918 IVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCL---DDGRWSGEEPSC 962
I + SV Y C + +G C D+G WSG P C
Sbjct: 236 IQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPEC 283
Score = 95.9 bits (228), Expect = 7e-19
Identities = 68/249 (27%), Positives = 106/249 (42%), Gaps = 19/249 (7%)
Query: 471 CPDPPAVSNASVTVNGHKA---GSLASYTCENGHI-LSGST-SVTCTLGGAWSGVPPSCK 525
C PP V NA + G + ++ +Y CE + + G SV C G WS + C
Sbjct: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCN 95
Query: 526 YVNCGTPT-IHKGSFVLINGTTTY---GSIAQFTCEPDYWLNGA--EELVCNRDGKWSYD 579
+C PT ++ S T Y G++ ++ C P Y + +L C ++ KWS
Sbjct: 96 R-SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTA 154
Query: 580 IPSCELTSCPEP-EVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDG---EWS 635
+ C+ SCP P E+ +G +TI+F C G+KL G + C G +WS
Sbjct: 155 VEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWS 214
Query: 636 GDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCT---EEF 692
P C I C P + G ++ + Y+C + ++G CT +E
Sbjct: 215 DPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEG 274
Query: 693 QWSDSSPRC 701
+WS P C
Sbjct: 275 EWSGPPPEC 283
Score = 91.5 bits (217), Expect = 2e-17
Identities = 78/271 (28%), Positives = 111/271 (40%), Gaps = 35/271 (12%)
Query: 645 DCGKLPTLPYGTMELLNGTTHL--GSVIQYSCTTNYRLVGPVRRT--CTEEFQWSDSSPR 700
DCG P +P L G T +VI Y C ++ + + + C + QWSD
Sbjct: 35 DCGLPPDVP-NAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEF 93
Query: 701 CEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVI 760
C C P N S I N + +G +V+Y C GY+
Sbjct: 94 CNR-SCEVPTRL---------NSASLKQPYITQ-------NYFPVGTVVEYECRPGYRR- 135
Query: 761 GESLS---TCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENW 817
SLS TC N +WS C+ C NPG I NG++ +P F GAT + C+ +
Sbjct: 136 EPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILF-GATISFSCNTGY 194
Query: 818 ELEGVIRRMCQENGT---WSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQ 874
+L G C +G+ WS P C+EI CP P QI G + Y
Sbjct: 195 KLFGSTSSFCLISGSSVQWSDPLPECREIYCPAP-PQIDNGI-IQGERDHYGYRQSVTYA 252
Query: 875 CERGYNLKGHQTRTCI---SKGQWNGTVPVC 902
C +G+ + G + C +G+W+G P C
Sbjct: 253 CNKGFTMIGEHSIYCTVNNDEGEWSGPPPEC 283
Score = 85.4 bits (202), Expect = 1e-15
Identities = 70/271 (25%), Positives = 111/271 (40%), Gaps = 38/271 (14%)
Query: 528 NCGTPTIHKGSFVLINGTTTY--GSIAQFTCEPDYWLNGAEE--LVCNRDGKWSYDIPSC 583
+CG P + + G T++ ++ + CE + E+ ++C + +WS DI
Sbjct: 35 DCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWS-DIEEF 93
Query: 584 ELTSCPEP-EVPSGGYMEAF---DYY-VHSTINFHCEAGHKLIGE--PNLVCQQDGEWSG 636
SC P + S + + +Y+ V + + + C G++ P L C Q+ +WS
Sbjct: 94 CNRSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWST 153
Query: 637 DSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCT---EEFQ 693
C+ C + G +++ G G+ I +SC T Y+L G C Q
Sbjct: 154 AVEFCKKKSCPNPGEIRNGQIDVPGGIL-FGATISFSCNTGYKLFGSTSSFCLISGSSVQ 212
Query: 694 WSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRC 753
WSD P C EI C P + I+ +R H Y V Y C
Sbjct: 213 WSDPLPECREIYCPAPPQIDNGIIQ---GERDH----------------YGYRQSVTYAC 253
Query: 754 EKGYKVIGESLSTC---EDNGQWSGTTPTCQ 781
KG+ +IGE C D G+WSG P C+
Sbjct: 254 NKGFTMIGEHSIYCTVNNDEGEWSGPPPECR 284
Score = 85.4 bits (202), Expect = 1e-15
Identities = 64/248 (25%), Positives = 101/248 (40%), Gaps = 20/248 (8%)
Query: 413 GLTPIEDGDVALIDNRTTHGARAL--YSCRENFTLVGNPERT--CGDEGIWDGEAPRCLF 468
GL P ++ RT+ + Y C E+F + + + C W C
Sbjct: 37 GLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNR 96
Query: 469 DWCPDPPAVSNAS-----VTVNGHKAGSLASYTCENGHILSGSTS--VTCTLGGAWSGVP 521
C P +++AS +T N G++ Y C G+ S S +TC WS
Sbjct: 97 S-CEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAV 155
Query: 522 PSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDG---KWSY 578
CK +C P + + + G +G+ F+C Y L G+ C G +WS
Sbjct: 156 EFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSD 215
Query: 579 DIPSCELTSCP-EPEVPSGGYMEAFDYY-VHSTINFHCEAGHKLIGEPNLVC---QQDGE 633
+P C CP P++ +G D+Y ++ + C G +IGE ++ C +GE
Sbjct: 216 PLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGE 275
Query: 634 WSGDSPTC 641
WSG P C
Sbjct: 276 WSGPPPEC 283
Score = 78.6 bits (185), Expect = 1e-13
Identities = 65/242 (26%), Positives = 97/242 (40%), Gaps = 21/242 (8%)
Query: 317 GEQNCVVLDGGRGWLWNDVGCNLDYLHWICQYLPPTCGSPDKLLNTTILGNDYDVGSRIV 376
GE++ V+ G W + CN C+ PT + L I N + VG+ +
Sbjct: 74 GEKDSVICLKGSQWSDIEEFCNRS-----CEV--PTRLNSASLKQPYITQNYFPVGTVVE 126
Query: 377 YKCPEGHMLLGDKSRH--CKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRTTHGAR 434
Y+C G+ S C ++ WS A CK +C I +G + + GA
Sbjct: 127 YECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQID-VPGGILFGAT 185
Query: 435 ALYSCRENFTLVGNPERTC---GDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGS 491
+SC + L G+ C G W P C +CP PP + N + G
Sbjct: 186 ISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGY 245
Query: 492 LAS--YTCENGHILSGSTSVTCTLG---GAWSGVPPSCKYVNCGT---PTIHKGSFVLIN 543
S Y C G + G S+ CT+ G WSG PP C+ + + PT+ K + V +
Sbjct: 246 RQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTVQKPTTVNVP 305
Query: 544 GT 545
T
Sbjct: 306 TT 307
Score = 74.9 bits (176), Expect = 1e-12
Identities = 66/267 (24%), Positives = 113/267 (42%), Gaps = 38/267 (14%)
Query: 591 PEVPSGG-YMEAFDYYVHST-INFHCEAGH-KLIGEPN-LVCQQDGEWSGDSPTCEYIDC 646
P+VP+ +E + T I + CE K+ GE + ++C + +WS C C
Sbjct: 40 PDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNR-SC 98
Query: 647 GKLPT-LPYGTME---LLNGTTHLGSVIQYSCTTNYRLVGPV--RRTCTEEFQWSDSSPR 700
++PT L +++ + +G+V++Y C YR + + TC + +WS +
Sbjct: 99 -EVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEF 157
Query: 701 CEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVI 760
C++ C +P + V G GA + + C GYK+
Sbjct: 158 CKKKSCPNPGEIRNGQIDVPGG--------------------ILFGATISFSCNTGYKLF 197
Query: 761 GESLSTCEDNG---QWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENW 817
G + S C +G QWS P C+ + C P +I+NG + + Y + Y C++ +
Sbjct: 198 GSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGF 257
Query: 818 ELEGVIRRMCQEN---GTWSLEPPICK 841
+ G C N G WS PP C+
Sbjct: 258 TMIGEHSIYCTVNNDEGEWSGPPPECR 284
Score = 73.3 bits (172), Expect = 4e-12
Identities = 53/191 (27%), Positives = 82/191 (42%), Gaps = 17/191 (8%)
Query: 784 DCGNPGRIENGKVTLPSNATFYGATAF-YQCDENW-----ELEGVIRRMCQENGTWSLEP 837
DCG P + N + L +F T Y+C+E++ E + VI C + WS
Sbjct: 35 DCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVI---CLKGSQWSDIE 91
Query: 838 PICKEITCPDPSAQIKAGSGLLVVTST-LSIGGEAHYQCERGYNLKGHQTR--TCISKGQ 894
C +C P+ A +T +G Y+C GY + + TC+ +
Sbjct: 92 EFCNR-SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLK 150
Query: 895 WNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDG- 953
W+ V C C +PG I NG+I + G LFG+++ + C + Y+ G CL G
Sbjct: 151 WSTAVEFCKKKSCPNPGEIRNGQIDVP-GGILFGATISFSCNTGYKLFGSTSSFCLISGS 209
Query: 954 --RWSGEEPSC 962
+WS P C
Sbjct: 210 SVQWSDPLPEC 220
Score = 34.3 bits (75), Expect = 2.4
Identities = 17/60 (28%), Positives = 28/60 (46%), Gaps = 5/60 (8%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRG---DWTLEPPFC 58
C +P N ++ +P I+ G + C+ GY+LFG+ C + G W+ P C
Sbjct: 163 CPNPGEIRNGQIDVPG--GILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPEC 220
Score = 32.3 bits (70), Expect = 9.7
Identities = 16/59 (27%), Positives = 29/59 (49%), Gaps = 2/59 (3%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGY-ELFGARQRECTLRG-DWTLEPPFC 58
CG P PNA+ ++ + T+ Y+C+E + ++ G + L+G W+ FC
Sbjct: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFC 94
>AL391597-4|CAH72948.1| 293|Homo sapiens CD55 molecule, decay
accelerating factor for complement (Cromer blood group)
protein.
Length = 293
Score = 97.5 bits (232), Expect = 2e-19
Identities = 65/228 (28%), Positives = 98/228 (42%), Gaps = 17/228 (7%)
Query: 748 LVKYRCEKGY-KVIGESLST-CEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFY 805
++ Y+CE+ + K+ GE S C QWS C C P R+ + + P Y
Sbjct: 37 VITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNR-SCEVPTRLNSASLKQPYITQNY 95
Query: 806 ---GATAFYQCDENWELEGVI--RRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLV 860
G Y+C + E + + C +N WS CK+ +CP+P +I+ +G +
Sbjct: 96 FPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPG-EIR--NGQID 152
Query: 861 VTSTLSIGGEAHYQCERGYNLKGHQTRTCISKG---QWNGTVPVCIPIDCRSPGNIENGK 917
V + G + C GY L G + C+ G QW+ +P C I C +P I+NG
Sbjct: 153 VPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGI 212
Query: 918 IVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCL---DDGRWSGEEPSC 962
I + SV Y C + +G C D+G WSG P C
Sbjct: 213 IQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPEC 260
Score = 95.9 bits (228), Expect = 7e-19
Identities = 68/249 (27%), Positives = 106/249 (42%), Gaps = 19/249 (7%)
Query: 471 CPDPPAVSNASVTVNGHKA---GSLASYTCENGHI-LSGST-SVTCTLGGAWSGVPPSCK 525
C PP V NA + G + ++ +Y CE + + G SV C G WS + C
Sbjct: 13 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCN 72
Query: 526 YVNCGTPT-IHKGSFVLINGTTTY---GSIAQFTCEPDYWLNGA--EELVCNRDGKWSYD 579
+C PT ++ S T Y G++ ++ C P Y + +L C ++ KWS
Sbjct: 73 R-SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTA 131
Query: 580 IPSCELTSCPEP-EVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDG---EWS 635
+ C+ SCP P E+ +G +TI+F C G+KL G + C G +WS
Sbjct: 132 VEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWS 191
Query: 636 GDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCT---EEF 692
P C I C P + G ++ + Y+C + ++G CT +E
Sbjct: 192 DPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEG 251
Query: 693 QWSDSSPRC 701
+WS P C
Sbjct: 252 EWSGPPPEC 260
Score = 91.5 bits (217), Expect = 2e-17
Identities = 78/271 (28%), Positives = 111/271 (40%), Gaps = 35/271 (12%)
Query: 645 DCGKLPTLPYGTMELLNGTTHL--GSVIQYSCTTNYRLVGPVRRT--CTEEFQWSDSSPR 700
DCG P +P L G T +VI Y C ++ + + + C + QWSD
Sbjct: 12 DCGLPPDVP-NAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEF 70
Query: 701 CEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVI 760
C C P N S I N + +G +V+Y C GY+
Sbjct: 71 CNR-SCEVPTRL---------NSASLKQPYITQ-------NYFPVGTVVEYECRPGYRR- 112
Query: 761 GESLS---TCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENW 817
SLS TC N +WS C+ C NPG I NG++ +P F GAT + C+ +
Sbjct: 113 EPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILF-GATISFSCNTGY 171
Query: 818 ELEGVIRRMCQENGT---WSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQ 874
+L G C +G+ WS P C+EI CP P QI G + Y
Sbjct: 172 KLFGSTSSFCLISGSSVQWSDPLPECREIYCPAP-PQIDNGI-IQGERDHYGYRQSVTYA 229
Query: 875 CERGYNLKGHQTRTCI---SKGQWNGTVPVC 902
C +G+ + G + C +G+W+G P C
Sbjct: 230 CNKGFTMIGEHSIYCTVNNDEGEWSGPPPEC 260
Score = 85.4 bits (202), Expect = 1e-15
Identities = 70/271 (25%), Positives = 111/271 (40%), Gaps = 38/271 (14%)
Query: 528 NCGTPTIHKGSFVLINGTTTY--GSIAQFTCEPDYWLNGAEE--LVCNRDGKWSYDIPSC 583
+CG P + + G T++ ++ + CE + E+ ++C + +WS DI
Sbjct: 12 DCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWS-DIEEF 70
Query: 584 ELTSCPEP-EVPSGGYMEAF---DYY-VHSTINFHCEAGHKLIGE--PNLVCQQDGEWSG 636
SC P + S + + +Y+ V + + + C G++ P L C Q+ +WS
Sbjct: 71 CNRSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWST 130
Query: 637 DSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCT---EEFQ 693
C+ C + G +++ G G+ I +SC T Y+L G C Q
Sbjct: 131 AVEFCKKKSCPNPGEIRNGQIDVPGGIL-FGATISFSCNTGYKLFGSTSSFCLISGSSVQ 189
Query: 694 WSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRC 753
WSD P C EI C P + I+ +R H Y V Y C
Sbjct: 190 WSDPLPECREIYCPAPPQIDNGIIQ---GERDH----------------YGYRQSVTYAC 230
Query: 754 EKGYKVIGESLSTC---EDNGQWSGTTPTCQ 781
KG+ +IGE C D G+WSG P C+
Sbjct: 231 NKGFTMIGEHSIYCTVNNDEGEWSGPPPECR 261
Score = 85.4 bits (202), Expect = 1e-15
Identities = 64/248 (25%), Positives = 101/248 (40%), Gaps = 20/248 (8%)
Query: 413 GLTPIEDGDVALIDNRTTHGARAL--YSCRENFTLVGNPERT--CGDEGIWDGEAPRCLF 468
GL P ++ RT+ + Y C E+F + + + C W C
Sbjct: 14 GLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNR 73
Query: 469 DWCPDPPAVSNAS-----VTVNGHKAGSLASYTCENGHILSGSTS--VTCTLGGAWSGVP 521
C P +++AS +T N G++ Y C G+ S S +TC WS
Sbjct: 74 S-CEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAV 132
Query: 522 PSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDG---KWSY 578
CK +C P + + + G +G+ F+C Y L G+ C G +WS
Sbjct: 133 EFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSD 192
Query: 579 DIPSCELTSCP-EPEVPSGGYMEAFDYY-VHSTINFHCEAGHKLIGEPNLVC---QQDGE 633
+P C CP P++ +G D+Y ++ + C G +IGE ++ C +GE
Sbjct: 193 PLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGE 252
Query: 634 WSGDSPTC 641
WSG P C
Sbjct: 253 WSGPPPEC 260
Score = 78.6 bits (185), Expect = 1e-13
Identities = 65/242 (26%), Positives = 97/242 (40%), Gaps = 21/242 (8%)
Query: 317 GEQNCVVLDGGRGWLWNDVGCNLDYLHWICQYLPPTCGSPDKLLNTTILGNDYDVGSRIV 376
GE++ V+ G W + CN C+ PT + L I N + VG+ +
Sbjct: 51 GEKDSVICLKGSQWSDIEEFCNRS-----CEV--PTRLNSASLKQPYITQNYFPVGTVVE 103
Query: 377 YKCPEGHMLLGDKSRH--CKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRTTHGAR 434
Y+C G+ S C ++ WS A CK +C I +G + + GA
Sbjct: 104 YECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQID-VPGGILFGAT 162
Query: 435 ALYSCRENFTLVGNPERTC---GDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGS 491
+SC + L G+ C G W P C +CP PP + N + G
Sbjct: 163 ISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGY 222
Query: 492 LAS--YTCENGHILSGSTSVTCTLG---GAWSGVPPSCKYVNCGT---PTIHKGSFVLIN 543
S Y C G + G S+ CT+ G WSG PP C+ + + PT+ K + V +
Sbjct: 223 RQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTVQKPTTVNVP 282
Query: 544 GT 545
T
Sbjct: 283 TT 284
Score = 74.9 bits (176), Expect = 1e-12
Identities = 66/267 (24%), Positives = 113/267 (42%), Gaps = 38/267 (14%)
Query: 591 PEVPSGG-YMEAFDYYVHST-INFHCEAGH-KLIGEPN-LVCQQDGEWSGDSPTCEYIDC 646
P+VP+ +E + T I + CE K+ GE + ++C + +WS C C
Sbjct: 17 PDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNR-SC 75
Query: 647 GKLPT-LPYGTME---LLNGTTHLGSVIQYSCTTNYRLVGPV--RRTCTEEFQWSDSSPR 700
++PT L +++ + +G+V++Y C YR + + TC + +WS +
Sbjct: 76 -EVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEF 134
Query: 701 CEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVI 760
C++ C +P + V G GA + + C GYK+
Sbjct: 135 CKKKSCPNPGEIRNGQIDVPGG--------------------ILFGATISFSCNTGYKLF 174
Query: 761 GESLSTCEDNG---QWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENW 817
G + S C +G QWS P C+ + C P +I+NG + + Y + Y C++ +
Sbjct: 175 GSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGF 234
Query: 818 ELEGVIRRMCQEN---GTWSLEPPICK 841
+ G C N G WS PP C+
Sbjct: 235 TMIGEHSIYCTVNNDEGEWSGPPPECR 261
Score = 73.3 bits (172), Expect = 4e-12
Identities = 53/191 (27%), Positives = 82/191 (42%), Gaps = 17/191 (8%)
Query: 784 DCGNPGRIENGKVTLPSNATFYGATAF-YQCDENW-----ELEGVIRRMCQENGTWSLEP 837
DCG P + N + L +F T Y+C+E++ E + VI C + WS
Sbjct: 12 DCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVI---CLKGSQWSDIE 68
Query: 838 PICKEITCPDPSAQIKAGSGLLVVTST-LSIGGEAHYQCERGYNLKGHQTR--TCISKGQ 894
C +C P+ A +T +G Y+C GY + + TC+ +
Sbjct: 69 EFCNR-SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLK 127
Query: 895 WNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDG- 953
W+ V C C +PG I NG+I + G LFG+++ + C + Y+ G CL G
Sbjct: 128 WSTAVEFCKKKSCPNPGEIRNGQIDVP-GGILFGATISFSCNTGYKLFGSTSSFCLISGS 186
Query: 954 --RWSGEEPSC 962
+WS P C
Sbjct: 187 SVQWSDPLPEC 197
Score = 34.3 bits (75), Expect = 2.4
Identities = 17/60 (28%), Positives = 28/60 (46%), Gaps = 5/60 (8%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRG---DWTLEPPFC 58
C +P N ++ +P I+ G + C+ GY+LFG+ C + G W+ P C
Sbjct: 140 CPNPGEIRNGQIDVPG--GILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPEC 197
Score = 32.3 bits (70), Expect = 9.7
Identities = 16/59 (27%), Positives = 29/59 (49%), Gaps = 2/59 (3%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGY-ELFGARQRECTLRG-DWTLEPPFC 58
CG P PNA+ ++ + T+ Y+C+E + ++ G + L+G W+ FC
Sbjct: 13 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFC 71
>AL391597-2|CAH72946.1| 381|Homo sapiens CD55 molecule, decay
accelerating factor for complement (Cromer blood group)
protein.
Length = 381
Score = 97.5 bits (232), Expect = 2e-19
Identities = 65/228 (28%), Positives = 98/228 (42%), Gaps = 17/228 (7%)
Query: 748 LVKYRCEKGY-KVIGESLST-CEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFY 805
++ Y+CE+ + K+ GE S C QWS C C P R+ + + P Y
Sbjct: 60 VITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNR-SCEVPTRLNSASLKQPYITQNY 118
Query: 806 ---GATAFYQCDENWELEGVI--RRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLV 860
G Y+C + E + + C +N WS CK+ +CP+P +I+ +G +
Sbjct: 119 FPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPG-EIR--NGQID 175
Query: 861 VTSTLSIGGEAHYQCERGYNLKGHQTRTCISKG---QWNGTVPVCIPIDCRSPGNIENGK 917
V + G + C GY L G + C+ G QW+ +P C I C +P I+NG
Sbjct: 176 VPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGI 235
Query: 918 IVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCL---DDGRWSGEEPSC 962
I + SV Y C + +G C D+G WSG P C
Sbjct: 236 IQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPEC 283
Score = 95.9 bits (228), Expect = 7e-19
Identities = 68/249 (27%), Positives = 106/249 (42%), Gaps = 19/249 (7%)
Query: 471 CPDPPAVSNASVTVNGHKA---GSLASYTCENGHI-LSGST-SVTCTLGGAWSGVPPSCK 525
C PP V NA + G + ++ +Y CE + + G SV C G WS + C
Sbjct: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCN 95
Query: 526 YVNCGTPT-IHKGSFVLINGTTTY---GSIAQFTCEPDYWLNGA--EELVCNRDGKWSYD 579
+C PT ++ S T Y G++ ++ C P Y + +L C ++ KWS
Sbjct: 96 R-SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTA 154
Query: 580 IPSCELTSCPEP-EVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDG---EWS 635
+ C+ SCP P E+ +G +TI+F C G+KL G + C G +WS
Sbjct: 155 VEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWS 214
Query: 636 GDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCT---EEF 692
P C I C P + G ++ + Y+C + ++G CT +E
Sbjct: 215 DPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEG 274
Query: 693 QWSDSSPRC 701
+WS P C
Sbjct: 275 EWSGPPPEC 283
Score = 91.5 bits (217), Expect = 2e-17
Identities = 78/271 (28%), Positives = 111/271 (40%), Gaps = 35/271 (12%)
Query: 645 DCGKLPTLPYGTMELLNGTTHL--GSVIQYSCTTNYRLVGPVRRT--CTEEFQWSDSSPR 700
DCG P +P L G T +VI Y C ++ + + + C + QWSD
Sbjct: 35 DCGLPPDVP-NAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEF 93
Query: 701 CEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVI 760
C C P N S I N + +G +V+Y C GY+
Sbjct: 94 CNR-SCEVPTRL---------NSASLKQPYITQ-------NYFPVGTVVEYECRPGYRR- 135
Query: 761 GESLS---TCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENW 817
SLS TC N +WS C+ C NPG I NG++ +P F GAT + C+ +
Sbjct: 136 EPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILF-GATISFSCNTGY 194
Query: 818 ELEGVIRRMCQENGT---WSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQ 874
+L G C +G+ WS P C+EI CP P QI G + Y
Sbjct: 195 KLFGSTSSFCLISGSSVQWSDPLPECREIYCPAP-PQIDNGI-IQGERDHYGYRQSVTYA 252
Query: 875 CERGYNLKGHQTRTCI---SKGQWNGTVPVC 902
C +G+ + G + C +G+W+G P C
Sbjct: 253 CNKGFTMIGEHSIYCTVNNDEGEWSGPPPEC 283
Score = 85.4 bits (202), Expect = 1e-15
Identities = 70/271 (25%), Positives = 111/271 (40%), Gaps = 38/271 (14%)
Query: 528 NCGTPTIHKGSFVLINGTTTY--GSIAQFTCEPDYWLNGAEE--LVCNRDGKWSYDIPSC 583
+CG P + + G T++ ++ + CE + E+ ++C + +WS DI
Sbjct: 35 DCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWS-DIEEF 93
Query: 584 ELTSCPEP-EVPSGGYMEAF---DYY-VHSTINFHCEAGHKLIGE--PNLVCQQDGEWSG 636
SC P + S + + +Y+ V + + + C G++ P L C Q+ +WS
Sbjct: 94 CNRSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWST 153
Query: 637 DSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCT---EEFQ 693
C+ C + G +++ G G+ I +SC T Y+L G C Q
Sbjct: 154 AVEFCKKKSCPNPGEIRNGQIDVPGGIL-FGATISFSCNTGYKLFGSTSSFCLISGSSVQ 212
Query: 694 WSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRC 753
WSD P C EI C P + I+ +R H Y V Y C
Sbjct: 213 WSDPLPECREIYCPAPPQIDNGIIQ---GERDH----------------YGYRQSVTYAC 253
Query: 754 EKGYKVIGESLSTC---EDNGQWSGTTPTCQ 781
KG+ +IGE C D G+WSG P C+
Sbjct: 254 NKGFTMIGEHSIYCTVNNDEGEWSGPPPECR 284
Score = 85.4 bits (202), Expect = 1e-15
Identities = 64/248 (25%), Positives = 101/248 (40%), Gaps = 20/248 (8%)
Query: 413 GLTPIEDGDVALIDNRTTHGARAL--YSCRENFTLVGNPERT--CGDEGIWDGEAPRCLF 468
GL P ++ RT+ + Y C E+F + + + C W C
Sbjct: 37 GLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNR 96
Query: 469 DWCPDPPAVSNAS-----VTVNGHKAGSLASYTCENGHILSGSTS--VTCTLGGAWSGVP 521
C P +++AS +T N G++ Y C G+ S S +TC WS
Sbjct: 97 S-CEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAV 155
Query: 522 PSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDG---KWSY 578
CK +C P + + + G +G+ F+C Y L G+ C G +WS
Sbjct: 156 EFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSD 215
Query: 579 DIPSCELTSCP-EPEVPSGGYMEAFDYY-VHSTINFHCEAGHKLIGEPNLVC---QQDGE 633
+P C CP P++ +G D+Y ++ + C G +IGE ++ C +GE
Sbjct: 216 PLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGE 275
Query: 634 WSGDSPTC 641
WSG P C
Sbjct: 276 WSGPPPEC 283
Score = 78.6 bits (185), Expect = 1e-13
Identities = 65/242 (26%), Positives = 97/242 (40%), Gaps = 21/242 (8%)
Query: 317 GEQNCVVLDGGRGWLWNDVGCNLDYLHWICQYLPPTCGSPDKLLNTTILGNDYDVGSRIV 376
GE++ V+ G W + CN C+ PT + L I N + VG+ +
Sbjct: 74 GEKDSVICLKGSQWSDIEEFCNRS-----CEV--PTRLNSASLKQPYITQNYFPVGTVVE 126
Query: 377 YKCPEGHMLLGDKSRH--CKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRTTHGAR 434
Y+C G+ S C ++ WS A CK +C I +G + + GA
Sbjct: 127 YECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQID-VPGGILFGAT 185
Query: 435 ALYSCRENFTLVGNPERTC---GDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGS 491
+SC + L G+ C G W P C +CP PP + N + G
Sbjct: 186 ISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGY 245
Query: 492 LAS--YTCENGHILSGSTSVTCTLG---GAWSGVPPSCKYVNCGT---PTIHKGSFVLIN 543
S Y C G + G S+ CT+ G WSG PP C+ + + PT+ K + V +
Sbjct: 246 RQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTVQKPTTVNVP 305
Query: 544 GT 545
T
Sbjct: 306 TT 307
Score = 74.9 bits (176), Expect = 1e-12
Identities = 66/267 (24%), Positives = 113/267 (42%), Gaps = 38/267 (14%)
Query: 591 PEVPSGG-YMEAFDYYVHST-INFHCEAGH-KLIGEPN-LVCQQDGEWSGDSPTCEYIDC 646
P+VP+ +E + T I + CE K+ GE + ++C + +WS C C
Sbjct: 40 PDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNR-SC 98
Query: 647 GKLPT-LPYGTME---LLNGTTHLGSVIQYSCTTNYRLVGPV--RRTCTEEFQWSDSSPR 700
++PT L +++ + +G+V++Y C YR + + TC + +WS +
Sbjct: 99 -EVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEF 157
Query: 701 CEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVI 760
C++ C +P + V G GA + + C GYK+
Sbjct: 158 CKKKSCPNPGEIRNGQIDVPGG--------------------ILFGATISFSCNTGYKLF 197
Query: 761 GESLSTCEDNG---QWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENW 817
G + S C +G QWS P C+ + C P +I+NG + + Y + Y C++ +
Sbjct: 198 GSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGF 257
Query: 818 ELEGVIRRMCQEN---GTWSLEPPICK 841
+ G C N G WS PP C+
Sbjct: 258 TMIGEHSIYCTVNNDEGEWSGPPPECR 284
Score = 73.3 bits (172), Expect = 4e-12
Identities = 53/191 (27%), Positives = 82/191 (42%), Gaps = 17/191 (8%)
Query: 784 DCGNPGRIENGKVTLPSNATFYGATAF-YQCDENW-----ELEGVIRRMCQENGTWSLEP 837
DCG P + N + L +F T Y+C+E++ E + VI C + WS
Sbjct: 35 DCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVI---CLKGSQWSDIE 91
Query: 838 PICKEITCPDPSAQIKAGSGLLVVTST-LSIGGEAHYQCERGYNLKGHQTR--TCISKGQ 894
C +C P+ A +T +G Y+C GY + + TC+ +
Sbjct: 92 EFCNR-SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLK 150
Query: 895 WNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDG- 953
W+ V C C +PG I NG+I + G LFG+++ + C + Y+ G CL G
Sbjct: 151 WSTAVEFCKKKSCPNPGEIRNGQIDVP-GGILFGATISFSCNTGYKLFGSTSSFCLISGS 209
Query: 954 --RWSGEEPSC 962
+WS P C
Sbjct: 210 SVQWSDPLPEC 220
Score = 34.3 bits (75), Expect = 2.4
Identities = 17/60 (28%), Positives = 28/60 (46%), Gaps = 5/60 (8%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRG---DWTLEPPFC 58
C +P N ++ +P I+ G + C+ GY+LFG+ C + G W+ P C
Sbjct: 163 CPNPGEIRNGQIDVPG--GILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPEC 220
Score = 32.3 bits (70), Expect = 9.7
Identities = 16/59 (27%), Positives = 29/59 (49%), Gaps = 2/59 (3%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGY-ELFGARQRECTLRG-DWTLEPPFC 58
CG P PNA+ ++ + T+ Y+C+E + ++ G + L+G W+ FC
Sbjct: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFC 94
>AL391597-1|CAH72945.1| 444|Homo sapiens CD55 molecule, decay
accelerating factor for complement (Cromer blood group)
protein.
Length = 444
Score = 97.5 bits (232), Expect = 2e-19
Identities = 65/228 (28%), Positives = 98/228 (42%), Gaps = 17/228 (7%)
Query: 748 LVKYRCEKGY-KVIGESLST-CEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFY 805
++ Y+CE+ + K+ GE S C QWS C C P R+ + + P Y
Sbjct: 60 VITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNR-SCEVPTRLNSASLKQPYITQNY 118
Query: 806 ---GATAFYQCDENWELEGVI--RRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLV 860
G Y+C + E + + C +N WS CK+ +CP+P +I+ +G +
Sbjct: 119 FPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPG-EIR--NGQID 175
Query: 861 VTSTLSIGGEAHYQCERGYNLKGHQTRTCISKG---QWNGTVPVCIPIDCRSPGNIENGK 917
V + G + C GY L G + C+ G QW+ +P C I C +P I+NG
Sbjct: 176 VPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGI 235
Query: 918 IVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCL---DDGRWSGEEPSC 962
I + SV Y C + +G C D+G WSG P C
Sbjct: 236 IQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPEC 283
Score = 95.9 bits (228), Expect = 7e-19
Identities = 68/249 (27%), Positives = 106/249 (42%), Gaps = 19/249 (7%)
Query: 471 CPDPPAVSNASVTVNGHKA---GSLASYTCENGHI-LSGST-SVTCTLGGAWSGVPPSCK 525
C PP V NA + G + ++ +Y CE + + G SV C G WS + C
Sbjct: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCN 95
Query: 526 YVNCGTPT-IHKGSFVLINGTTTY---GSIAQFTCEPDYWLNGA--EELVCNRDGKWSYD 579
+C PT ++ S T Y G++ ++ C P Y + +L C ++ KWS
Sbjct: 96 R-SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTA 154
Query: 580 IPSCELTSCPEP-EVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDG---EWS 635
+ C+ SCP P E+ +G +TI+F C G+KL G + C G +WS
Sbjct: 155 VEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWS 214
Query: 636 GDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCT---EEF 692
P C I C P + G ++ + Y+C + ++G CT +E
Sbjct: 215 DPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEG 274
Query: 693 QWSDSSPRC 701
+WS P C
Sbjct: 275 EWSGPPPEC 283
Score = 91.5 bits (217), Expect = 2e-17
Identities = 78/271 (28%), Positives = 111/271 (40%), Gaps = 35/271 (12%)
Query: 645 DCGKLPTLPYGTMELLNGTTHL--GSVIQYSCTTNYRLVGPVRRT--CTEEFQWSDSSPR 700
DCG P +P L G T +VI Y C ++ + + + C + QWSD
Sbjct: 35 DCGLPPDVP-NAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEF 93
Query: 701 CEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVI 760
C C P N S I N + +G +V+Y C GY+
Sbjct: 94 CNR-SCEVPTRL---------NSASLKQPYITQ-------NYFPVGTVVEYECRPGYRR- 135
Query: 761 GESLS---TCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENW 817
SLS TC N +WS C+ C NPG I NG++ +P F GAT + C+ +
Sbjct: 136 EPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILF-GATISFSCNTGY 194
Query: 818 ELEGVIRRMCQENGT---WSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQ 874
+L G C +G+ WS P C+EI CP P QI G + Y
Sbjct: 195 KLFGSTSSFCLISGSSVQWSDPLPECREIYCPAP-PQIDNGI-IQGERDHYGYRQSVTYA 252
Query: 875 CERGYNLKGHQTRTCI---SKGQWNGTVPVC 902
C +G+ + G + C +G+W+G P C
Sbjct: 253 CNKGFTMIGEHSIYCTVNNDEGEWSGPPPEC 283
Score = 85.4 bits (202), Expect = 1e-15
Identities = 70/271 (25%), Positives = 111/271 (40%), Gaps = 38/271 (14%)
Query: 528 NCGTPTIHKGSFVLINGTTTY--GSIAQFTCEPDYWLNGAEE--LVCNRDGKWSYDIPSC 583
+CG P + + G T++ ++ + CE + E+ ++C + +WS DI
Sbjct: 35 DCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWS-DIEEF 93
Query: 584 ELTSCPEP-EVPSGGYMEAF---DYY-VHSTINFHCEAGHKLIGE--PNLVCQQDGEWSG 636
SC P + S + + +Y+ V + + + C G++ P L C Q+ +WS
Sbjct: 94 CNRSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWST 153
Query: 637 DSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCT---EEFQ 693
C+ C + G +++ G G+ I +SC T Y+L G C Q
Sbjct: 154 AVEFCKKKSCPNPGEIRNGQIDVPGGIL-FGATISFSCNTGYKLFGSTSSFCLISGSSVQ 212
Query: 694 WSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRC 753
WSD P C EI C P + I+ +R H Y V Y C
Sbjct: 213 WSDPLPECREIYCPAPPQIDNGIIQ---GERDH----------------YGYRQSVTYAC 253
Query: 754 EKGYKVIGESLSTC---EDNGQWSGTTPTCQ 781
KG+ +IGE C D G+WSG P C+
Sbjct: 254 NKGFTMIGEHSIYCTVNNDEGEWSGPPPECR 284
Score = 85.4 bits (202), Expect = 1e-15
Identities = 64/248 (25%), Positives = 101/248 (40%), Gaps = 20/248 (8%)
Query: 413 GLTPIEDGDVALIDNRTTHGARAL--YSCRENFTLVGNPERT--CGDEGIWDGEAPRCLF 468
GL P ++ RT+ + Y C E+F + + + C W C
Sbjct: 37 GLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNR 96
Query: 469 DWCPDPPAVSNAS-----VTVNGHKAGSLASYTCENGHILSGSTS--VTCTLGGAWSGVP 521
C P +++AS +T N G++ Y C G+ S S +TC WS
Sbjct: 97 S-CEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAV 155
Query: 522 PSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDG---KWSY 578
CK +C P + + + G +G+ F+C Y L G+ C G +WS
Sbjct: 156 EFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSD 215
Query: 579 DIPSCELTSCP-EPEVPSGGYMEAFDYY-VHSTINFHCEAGHKLIGEPNLVC---QQDGE 633
+P C CP P++ +G D+Y ++ + C G +IGE ++ C +GE
Sbjct: 216 PLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGE 275
Query: 634 WSGDSPTC 641
WSG P C
Sbjct: 276 WSGPPPEC 283
Score = 78.6 bits (185), Expect = 1e-13
Identities = 65/242 (26%), Positives = 97/242 (40%), Gaps = 21/242 (8%)
Query: 317 GEQNCVVLDGGRGWLWNDVGCNLDYLHWICQYLPPTCGSPDKLLNTTILGNDYDVGSRIV 376
GE++ V+ G W + CN C+ PT + L I N + VG+ +
Sbjct: 74 GEKDSVICLKGSQWSDIEEFCNRS-----CEV--PTRLNSASLKQPYITQNYFPVGTVVE 126
Query: 377 YKCPEGHMLLGDKSRH--CKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRTTHGAR 434
Y+C G+ S C ++ WS A CK +C I +G + + GA
Sbjct: 127 YECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQID-VPGGILFGAT 185
Query: 435 ALYSCRENFTLVGNPERTC---GDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGS 491
+SC + L G+ C G W P C +CP PP + N + G
Sbjct: 186 ISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGY 245
Query: 492 LAS--YTCENGHILSGSTSVTCTLG---GAWSGVPPSCKYVNCGT---PTIHKGSFVLIN 543
S Y C G + G S+ CT+ G WSG PP C+ + + PT+ K + V +
Sbjct: 246 RQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTVQKPTTVNVP 305
Query: 544 GT 545
T
Sbjct: 306 TT 307
Score = 74.9 bits (176), Expect = 1e-12
Identities = 66/267 (24%), Positives = 113/267 (42%), Gaps = 38/267 (14%)
Query: 591 PEVPSGG-YMEAFDYYVHST-INFHCEAGH-KLIGEPN-LVCQQDGEWSGDSPTCEYIDC 646
P+VP+ +E + T I + CE K+ GE + ++C + +WS C C
Sbjct: 40 PDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNR-SC 98
Query: 647 GKLPT-LPYGTME---LLNGTTHLGSVIQYSCTTNYRLVGPV--RRTCTEEFQWSDSSPR 700
++PT L +++ + +G+V++Y C YR + + TC + +WS +
Sbjct: 99 -EVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEF 157
Query: 701 CEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVI 760
C++ C +P + V G GA + + C GYK+
Sbjct: 158 CKKKSCPNPGEIRNGQIDVPGG--------------------ILFGATISFSCNTGYKLF 197
Query: 761 GESLSTCEDNG---QWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENW 817
G + S C +G QWS P C+ + C P +I+NG + + Y + Y C++ +
Sbjct: 198 GSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGF 257
Query: 818 ELEGVIRRMCQEN---GTWSLEPPICK 841
+ G C N G WS PP C+
Sbjct: 258 TMIGEHSIYCTVNNDEGEWSGPPPECR 284
Score = 73.3 bits (172), Expect = 4e-12
Identities = 53/191 (27%), Positives = 82/191 (42%), Gaps = 17/191 (8%)
Query: 784 DCGNPGRIENGKVTLPSNATFYGATAF-YQCDENW-----ELEGVIRRMCQENGTWSLEP 837
DCG P + N + L +F T Y+C+E++ E + VI C + WS
Sbjct: 35 DCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVI---CLKGSQWSDIE 91
Query: 838 PICKEITCPDPSAQIKAGSGLLVVTST-LSIGGEAHYQCERGYNLKGHQTR--TCISKGQ 894
C +C P+ A +T +G Y+C GY + + TC+ +
Sbjct: 92 EFCNR-SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLK 150
Query: 895 WNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDG- 953
W+ V C C +PG I NG+I + G LFG+++ + C + Y+ G CL G
Sbjct: 151 WSTAVEFCKKKSCPNPGEIRNGQIDVP-GGILFGATISFSCNTGYKLFGSTSSFCLISGS 209
Query: 954 --RWSGEEPSC 962
+WS P C
Sbjct: 210 SVQWSDPLPEC 220
Score = 34.3 bits (75), Expect = 2.4
Identities = 17/60 (28%), Positives = 28/60 (46%), Gaps = 5/60 (8%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRG---DWTLEPPFC 58
C +P N ++ +P I+ G + C+ GY+LFG+ C + G W+ P C
Sbjct: 163 CPNPGEIRNGQIDVPG--GILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPEC 220
Score = 32.3 bits (70), Expect = 9.7
Identities = 16/59 (27%), Positives = 29/59 (49%), Gaps = 2/59 (3%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGY-ELFGARQRECTLRG-DWTLEPPFC 58
CG P PNA+ ++ + T+ Y+C+E + ++ G + L+G W+ FC
Sbjct: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFC 94
>AB240570-1|BAE97426.1| 551|Homo sapiens decay-accelerating factor
splicing variant 5 protein.
Length = 551
Score = 97.5 bits (232), Expect = 2e-19
Identities = 65/228 (28%), Positives = 98/228 (42%), Gaps = 17/228 (7%)
Query: 748 LVKYRCEKGY-KVIGESLST-CEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFY 805
++ Y+CE+ + K+ GE S C QWS C C P R+ + + P Y
Sbjct: 60 VITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNR-SCEVPTRLNSASLKQPYITQNY 118
Query: 806 ---GATAFYQCDENWELEGVI--RRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLV 860
G Y+C + E + + C +N WS CK+ +CP+P +I+ +G +
Sbjct: 119 FPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPG-EIR--NGQID 175
Query: 861 VTSTLSIGGEAHYQCERGYNLKGHQTRTCISKG---QWNGTVPVCIPIDCRSPGNIENGK 917
V + G + C GY L G + C+ G QW+ +P C I C +P I+NG
Sbjct: 176 VPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGI 235
Query: 918 IVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCL---DDGRWSGEEPSC 962
I + SV Y C + +G C D+G WSG P C
Sbjct: 236 IQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPEC 283
Score = 95.9 bits (228), Expect = 7e-19
Identities = 68/249 (27%), Positives = 106/249 (42%), Gaps = 19/249 (7%)
Query: 471 CPDPPAVSNASVTVNGHKA---GSLASYTCENGHI-LSGST-SVTCTLGGAWSGVPPSCK 525
C PP V NA + G + ++ +Y CE + + G SV C G WS + C
Sbjct: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCN 95
Query: 526 YVNCGTPT-IHKGSFVLINGTTTY---GSIAQFTCEPDYWLNGA--EELVCNRDGKWSYD 579
+C PT ++ S T Y G++ ++ C P Y + +L C ++ KWS
Sbjct: 96 R-SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTA 154
Query: 580 IPSCELTSCPEP-EVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDG---EWS 635
+ C+ SCP P E+ +G +TI+F C G+KL G + C G +WS
Sbjct: 155 VEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWS 214
Query: 636 GDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCT---EEF 692
P C I C P + G ++ + Y+C + ++G CT +E
Sbjct: 215 DPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEG 274
Query: 693 QWSDSSPRC 701
+WS P C
Sbjct: 275 EWSGPPPEC 283
Score = 91.5 bits (217), Expect = 2e-17
Identities = 78/271 (28%), Positives = 111/271 (40%), Gaps = 35/271 (12%)
Query: 645 DCGKLPTLPYGTMELLNGTTHL--GSVIQYSCTTNYRLVGPVRRT--CTEEFQWSDSSPR 700
DCG P +P L G T +VI Y C ++ + + + C + QWSD
Sbjct: 35 DCGLPPDVP-NAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEF 93
Query: 701 CEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVI 760
C C P N S I N + +G +V+Y C GY+
Sbjct: 94 CNR-SCEVPTRL---------NSASLKQPYITQ-------NYFPVGTVVEYECRPGYRR- 135
Query: 761 GESLS---TCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENW 817
SLS TC N +WS C+ C NPG I NG++ +P F GAT + C+ +
Sbjct: 136 EPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILF-GATISFSCNTGY 194
Query: 818 ELEGVIRRMCQENGT---WSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQ 874
+L G C +G+ WS P C+EI CP P QI G + Y
Sbjct: 195 KLFGSTSSFCLISGSSVQWSDPLPECREIYCPAP-PQIDNGI-IQGERDHYGYRQSVTYA 252
Query: 875 CERGYNLKGHQTRTCI---SKGQWNGTVPVC 902
C +G+ + G + C +G+W+G P C
Sbjct: 253 CNKGFTMIGEHSIYCTVNNDEGEWSGPPPEC 283
Score = 85.4 bits (202), Expect = 1e-15
Identities = 70/271 (25%), Positives = 111/271 (40%), Gaps = 38/271 (14%)
Query: 528 NCGTPTIHKGSFVLINGTTTY--GSIAQFTCEPDYWLNGAEE--LVCNRDGKWSYDIPSC 583
+CG P + + G T++ ++ + CE + E+ ++C + +WS DI
Sbjct: 35 DCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWS-DIEEF 93
Query: 584 ELTSCPEP-EVPSGGYMEAF---DYY-VHSTINFHCEAGHKLIGE--PNLVCQQDGEWSG 636
SC P + S + + +Y+ V + + + C G++ P L C Q+ +WS
Sbjct: 94 CNRSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWST 153
Query: 637 DSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCT---EEFQ 693
C+ C + G +++ G G+ I +SC T Y+L G C Q
Sbjct: 154 AVEFCKKKSCPNPGEIRNGQIDVPGGIL-FGATISFSCNTGYKLFGSTSSFCLISGSSVQ 212
Query: 694 WSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRC 753
WSD P C EI C P + I+ +R H Y V Y C
Sbjct: 213 WSDPLPECREIYCPAPPQIDNGIIQ---GERDH----------------YGYRQSVTYAC 253
Query: 754 EKGYKVIGESLSTC---EDNGQWSGTTPTCQ 781
KG+ +IGE C D G+WSG P C+
Sbjct: 254 NKGFTMIGEHSIYCTVNNDEGEWSGPPPECR 284
Score = 85.4 bits (202), Expect = 1e-15
Identities = 64/248 (25%), Positives = 101/248 (40%), Gaps = 20/248 (8%)
Query: 413 GLTPIEDGDVALIDNRTTHGARAL--YSCRENFTLVGNPERT--CGDEGIWDGEAPRCLF 468
GL P ++ RT+ + Y C E+F + + + C W C
Sbjct: 37 GLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNR 96
Query: 469 DWCPDPPAVSNAS-----VTVNGHKAGSLASYTCENGHILSGSTS--VTCTLGGAWSGVP 521
C P +++AS +T N G++ Y C G+ S S +TC WS
Sbjct: 97 S-CEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAV 155
Query: 522 PSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDG---KWSY 578
CK +C P + + + G +G+ F+C Y L G+ C G +WS
Sbjct: 156 EFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSD 215
Query: 579 DIPSCELTSCP-EPEVPSGGYMEAFDYY-VHSTINFHCEAGHKLIGEPNLVC---QQDGE 633
+P C CP P++ +G D+Y ++ + C G +IGE ++ C +GE
Sbjct: 216 PLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGE 275
Query: 634 WSGDSPTC 641
WSG P C
Sbjct: 276 WSGPPPEC 283
Score = 78.6 bits (185), Expect = 1e-13
Identities = 65/242 (26%), Positives = 97/242 (40%), Gaps = 21/242 (8%)
Query: 317 GEQNCVVLDGGRGWLWNDVGCNLDYLHWICQYLPPTCGSPDKLLNTTILGNDYDVGSRIV 376
GE++ V+ G W + CN C+ PT + L I N + VG+ +
Sbjct: 74 GEKDSVICLKGSQWSDIEEFCNRS-----CEV--PTRLNSASLKQPYITQNYFPVGTVVE 126
Query: 377 YKCPEGHMLLGDKSRH--CKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRTTHGAR 434
Y+C G+ S C ++ WS A CK +C I +G + + GA
Sbjct: 127 YECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQID-VPGGILFGAT 185
Query: 435 ALYSCRENFTLVGNPERTC---GDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGS 491
+SC + L G+ C G W P C +CP PP + N + G
Sbjct: 186 ISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGY 245
Query: 492 LAS--YTCENGHILSGSTSVTCTLG---GAWSGVPPSCKYVNCGT---PTIHKGSFVLIN 543
S Y C G + G S+ CT+ G WSG PP C+ + + PT+ K + V +
Sbjct: 246 RQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTVQKPTTVNVP 305
Query: 544 GT 545
T
Sbjct: 306 TT 307
Score = 74.9 bits (176), Expect = 1e-12
Identities = 66/267 (24%), Positives = 113/267 (42%), Gaps = 38/267 (14%)
Query: 591 PEVPSGG-YMEAFDYYVHST-INFHCEAGH-KLIGEPN-LVCQQDGEWSGDSPTCEYIDC 646
P+VP+ +E + T I + CE K+ GE + ++C + +WS C C
Sbjct: 40 PDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNR-SC 98
Query: 647 GKLPT-LPYGTME---LLNGTTHLGSVIQYSCTTNYRLVGPV--RRTCTEEFQWSDSSPR 700
++PT L +++ + +G+V++Y C YR + + TC + +WS +
Sbjct: 99 -EVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEF 157
Query: 701 CEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVI 760
C++ C +P + V G GA + + C GYK+
Sbjct: 158 CKKKSCPNPGEIRNGQIDVPGG--------------------ILFGATISFSCNTGYKLF 197
Query: 761 GESLSTCEDNG---QWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENW 817
G + S C +G QWS P C+ + C P +I+NG + + Y + Y C++ +
Sbjct: 198 GSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGF 257
Query: 818 ELEGVIRRMCQEN---GTWSLEPPICK 841
+ G C N G WS PP C+
Sbjct: 258 TMIGEHSIYCTVNNDEGEWSGPPPECR 284
Score = 73.3 bits (172), Expect = 4e-12
Identities = 53/191 (27%), Positives = 82/191 (42%), Gaps = 17/191 (8%)
Query: 784 DCGNPGRIENGKVTLPSNATFYGATAF-YQCDENW-----ELEGVIRRMCQENGTWSLEP 837
DCG P + N + L +F T Y+C+E++ E + VI C + WS
Sbjct: 35 DCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVI---CLKGSQWSDIE 91
Query: 838 PICKEITCPDPSAQIKAGSGLLVVTST-LSIGGEAHYQCERGYNLKGHQTR--TCISKGQ 894
C +C P+ A +T +G Y+C GY + + TC+ +
Sbjct: 92 EFCNR-SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLK 150
Query: 895 WNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDG- 953
W+ V C C +PG I NG+I + G LFG+++ + C + Y+ G CL G
Sbjct: 151 WSTAVEFCKKKSCPNPGEIRNGQIDVP-GGILFGATISFSCNTGYKLFGSTSSFCLISGS 209
Query: 954 --RWSGEEPSC 962
+WS P C
Sbjct: 210 SVQWSDPLPEC 220
Score = 34.3 bits (75), Expect = 2.4
Identities = 17/60 (28%), Positives = 28/60 (46%), Gaps = 5/60 (8%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRG---DWTLEPPFC 58
C +P N ++ +P I+ G + C+ GY+LFG+ C + G W+ P C
Sbjct: 163 CPNPGEIRNGQIDVPG--GILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPEC 220
Score = 32.3 bits (70), Expect = 9.7
Identities = 16/59 (27%), Positives = 29/59 (49%), Gaps = 2/59 (3%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGY-ELFGARQRECTLRG-DWTLEPPFC 58
CG P PNA+ ++ + T+ Y+C+E + ++ G + L+G W+ FC
Sbjct: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFC 94
>AB240569-1|BAE97425.1| 525|Homo sapiens decay-accelerating factor
splicing variant 4 protein.
Length = 525
Score = 97.5 bits (232), Expect = 2e-19
Identities = 65/228 (28%), Positives = 98/228 (42%), Gaps = 17/228 (7%)
Query: 748 LVKYRCEKGY-KVIGESLST-CEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFY 805
++ Y+CE+ + K+ GE S C QWS C C P R+ + + P Y
Sbjct: 60 VITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNR-SCEVPTRLNSASLKQPYITQNY 118
Query: 806 ---GATAFYQCDENWELEGVI--RRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLV 860
G Y+C + E + + C +N WS CK+ +CP+P +I+ +G +
Sbjct: 119 FPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPG-EIR--NGQID 175
Query: 861 VTSTLSIGGEAHYQCERGYNLKGHQTRTCISKG---QWNGTVPVCIPIDCRSPGNIENGK 917
V + G + C GY L G + C+ G QW+ +P C I C +P I+NG
Sbjct: 176 VPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGI 235
Query: 918 IVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCL---DDGRWSGEEPSC 962
I + SV Y C + +G C D+G WSG P C
Sbjct: 236 IQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPEC 283
Score = 95.9 bits (228), Expect = 7e-19
Identities = 68/249 (27%), Positives = 106/249 (42%), Gaps = 19/249 (7%)
Query: 471 CPDPPAVSNASVTVNGHKA---GSLASYTCENGHI-LSGST-SVTCTLGGAWSGVPPSCK 525
C PP V NA + G + ++ +Y CE + + G SV C G WS + C
Sbjct: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCN 95
Query: 526 YVNCGTPT-IHKGSFVLINGTTTY---GSIAQFTCEPDYWLNGA--EELVCNRDGKWSYD 579
+C PT ++ S T Y G++ ++ C P Y + +L C ++ KWS
Sbjct: 96 R-SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTA 154
Query: 580 IPSCELTSCPEP-EVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDG---EWS 635
+ C+ SCP P E+ +G +TI+F C G+KL G + C G +WS
Sbjct: 155 VEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWS 214
Query: 636 GDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCT---EEF 692
P C I C P + G ++ + Y+C + ++G CT +E
Sbjct: 215 DPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEG 274
Query: 693 QWSDSSPRC 701
+WS P C
Sbjct: 275 EWSGPPPEC 283
Score = 91.5 bits (217), Expect = 2e-17
Identities = 78/271 (28%), Positives = 111/271 (40%), Gaps = 35/271 (12%)
Query: 645 DCGKLPTLPYGTMELLNGTTHL--GSVIQYSCTTNYRLVGPVRRT--CTEEFQWSDSSPR 700
DCG P +P L G T +VI Y C ++ + + + C + QWSD
Sbjct: 35 DCGLPPDVP-NAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEF 93
Query: 701 CEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVI 760
C C P N S I N + +G +V+Y C GY+
Sbjct: 94 CNR-SCEVPTRL---------NSASLKQPYITQ-------NYFPVGTVVEYECRPGYRR- 135
Query: 761 GESLS---TCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENW 817
SLS TC N +WS C+ C NPG I NG++ +P F GAT + C+ +
Sbjct: 136 EPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILF-GATISFSCNTGY 194
Query: 818 ELEGVIRRMCQENGT---WSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQ 874
+L G C +G+ WS P C+EI CP P QI G + Y
Sbjct: 195 KLFGSTSSFCLISGSSVQWSDPLPECREIYCPAP-PQIDNGI-IQGERDHYGYRQSVTYA 252
Query: 875 CERGYNLKGHQTRTCI---SKGQWNGTVPVC 902
C +G+ + G + C +G+W+G P C
Sbjct: 253 CNKGFTMIGEHSIYCTVNNDEGEWSGPPPEC 283
Score = 85.4 bits (202), Expect = 1e-15
Identities = 70/271 (25%), Positives = 111/271 (40%), Gaps = 38/271 (14%)
Query: 528 NCGTPTIHKGSFVLINGTTTY--GSIAQFTCEPDYWLNGAEE--LVCNRDGKWSYDIPSC 583
+CG P + + G T++ ++ + CE + E+ ++C + +WS DI
Sbjct: 35 DCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWS-DIEEF 93
Query: 584 ELTSCPEP-EVPSGGYMEAF---DYY-VHSTINFHCEAGHKLIGE--PNLVCQQDGEWSG 636
SC P + S + + +Y+ V + + + C G++ P L C Q+ +WS
Sbjct: 94 CNRSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWST 153
Query: 637 DSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCT---EEFQ 693
C+ C + G +++ G G+ I +SC T Y+L G C Q
Sbjct: 154 AVEFCKKKSCPNPGEIRNGQIDVPGGIL-FGATISFSCNTGYKLFGSTSSFCLISGSSVQ 212
Query: 694 WSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRC 753
WSD P C EI C P + I+ +R H Y V Y C
Sbjct: 213 WSDPLPECREIYCPAPPQIDNGIIQ---GERDH----------------YGYRQSVTYAC 253
Query: 754 EKGYKVIGESLSTC---EDNGQWSGTTPTCQ 781
KG+ +IGE C D G+WSG P C+
Sbjct: 254 NKGFTMIGEHSIYCTVNNDEGEWSGPPPECR 284
Score = 85.4 bits (202), Expect = 1e-15
Identities = 64/248 (25%), Positives = 101/248 (40%), Gaps = 20/248 (8%)
Query: 413 GLTPIEDGDVALIDNRTTHGARAL--YSCRENFTLVGNPERT--CGDEGIWDGEAPRCLF 468
GL P ++ RT+ + Y C E+F + + + C W C
Sbjct: 37 GLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNR 96
Query: 469 DWCPDPPAVSNAS-----VTVNGHKAGSLASYTCENGHILSGSTS--VTCTLGGAWSGVP 521
C P +++AS +T N G++ Y C G+ S S +TC WS
Sbjct: 97 S-CEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAV 155
Query: 522 PSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDG---KWSY 578
CK +C P + + + G +G+ F+C Y L G+ C G +WS
Sbjct: 156 EFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSD 215
Query: 579 DIPSCELTSCP-EPEVPSGGYMEAFDYY-VHSTINFHCEAGHKLIGEPNLVC---QQDGE 633
+P C CP P++ +G D+Y ++ + C G +IGE ++ C +GE
Sbjct: 216 PLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGE 275
Query: 634 WSGDSPTC 641
WSG P C
Sbjct: 276 WSGPPPEC 283
Score = 78.6 bits (185), Expect = 1e-13
Identities = 65/242 (26%), Positives = 97/242 (40%), Gaps = 21/242 (8%)
Query: 317 GEQNCVVLDGGRGWLWNDVGCNLDYLHWICQYLPPTCGSPDKLLNTTILGNDYDVGSRIV 376
GE++ V+ G W + CN C+ PT + L I N + VG+ +
Sbjct: 74 GEKDSVICLKGSQWSDIEEFCNRS-----CEV--PTRLNSASLKQPYITQNYFPVGTVVE 126
Query: 377 YKCPEGHMLLGDKSRH--CKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRTTHGAR 434
Y+C G+ S C ++ WS A CK +C I +G + + GA
Sbjct: 127 YECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQID-VPGGILFGAT 185
Query: 435 ALYSCRENFTLVGNPERTC---GDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGS 491
+SC + L G+ C G W P C +CP PP + N + G
Sbjct: 186 ISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGY 245
Query: 492 LAS--YTCENGHILSGSTSVTCTLG---GAWSGVPPSCKYVNCGT---PTIHKGSFVLIN 543
S Y C G + G S+ CT+ G WSG PP C+ + + PT+ K + V +
Sbjct: 246 RQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTVQKPTTVNVP 305
Query: 544 GT 545
T
Sbjct: 306 TT 307
Score = 74.9 bits (176), Expect = 1e-12
Identities = 66/267 (24%), Positives = 113/267 (42%), Gaps = 38/267 (14%)
Query: 591 PEVPSGG-YMEAFDYYVHST-INFHCEAGH-KLIGEPN-LVCQQDGEWSGDSPTCEYIDC 646
P+VP+ +E + T I + CE K+ GE + ++C + +WS C C
Sbjct: 40 PDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNR-SC 98
Query: 647 GKLPT-LPYGTME---LLNGTTHLGSVIQYSCTTNYRLVGPV--RRTCTEEFQWSDSSPR 700
++PT L +++ + +G+V++Y C YR + + TC + +WS +
Sbjct: 99 -EVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEF 157
Query: 701 CEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVI 760
C++ C +P + V G GA + + C GYK+
Sbjct: 158 CKKKSCPNPGEIRNGQIDVPGG--------------------ILFGATISFSCNTGYKLF 197
Query: 761 GESLSTCEDNG---QWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENW 817
G + S C +G QWS P C+ + C P +I+NG + + Y + Y C++ +
Sbjct: 198 GSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGF 257
Query: 818 ELEGVIRRMCQEN---GTWSLEPPICK 841
+ G C N G WS PP C+
Sbjct: 258 TMIGEHSIYCTVNNDEGEWSGPPPECR 284
Score = 73.3 bits (172), Expect = 4e-12
Identities = 53/191 (27%), Positives = 82/191 (42%), Gaps = 17/191 (8%)
Query: 784 DCGNPGRIENGKVTLPSNATFYGATAF-YQCDENW-----ELEGVIRRMCQENGTWSLEP 837
DCG P + N + L +F T Y+C+E++ E + VI C + WS
Sbjct: 35 DCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVI---CLKGSQWSDIE 91
Query: 838 PICKEITCPDPSAQIKAGSGLLVVTST-LSIGGEAHYQCERGYNLKGHQTR--TCISKGQ 894
C +C P+ A +T +G Y+C GY + + TC+ +
Sbjct: 92 EFCNR-SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLK 150
Query: 895 WNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDG- 953
W+ V C C +PG I NG+I + G LFG+++ + C + Y+ G CL G
Sbjct: 151 WSTAVEFCKKKSCPNPGEIRNGQIDVP-GGILFGATISFSCNTGYKLFGSTSSFCLISGS 209
Query: 954 --RWSGEEPSC 962
+WS P C
Sbjct: 210 SVQWSDPLPEC 220
Score = 34.3 bits (75), Expect = 2.4
Identities = 17/60 (28%), Positives = 28/60 (46%), Gaps = 5/60 (8%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRG---DWTLEPPFC 58
C +P N ++ +P I+ G + C+ GY+LFG+ C + G W+ P C
Sbjct: 163 CPNPGEIRNGQIDVPG--GILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPEC 220
Score = 32.3 bits (70), Expect = 9.7
Identities = 16/59 (27%), Positives = 29/59 (49%), Gaps = 2/59 (3%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGY-ELFGARQRECTLRG-DWTLEPPFC 58
CG P PNA+ ++ + T+ Y+C+E + ++ G + L+G W+ FC
Sbjct: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFC 94
>AB240568-1|BAE97424.1| 384|Homo sapiens decay-accelerating factor
splicing variant 3 protein.
Length = 384
Score = 97.5 bits (232), Expect = 2e-19
Identities = 65/228 (28%), Positives = 98/228 (42%), Gaps = 17/228 (7%)
Query: 748 LVKYRCEKGY-KVIGESLST-CEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFY 805
++ Y+CE+ + K+ GE S C QWS C C P R+ + + P Y
Sbjct: 60 VITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNR-SCEVPTRLNSASLKQPYITQNY 118
Query: 806 ---GATAFYQCDENWELEGVI--RRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLV 860
G Y+C + E + + C +N WS CK+ +CP+P +I+ +G +
Sbjct: 119 FPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPG-EIR--NGQID 175
Query: 861 VTSTLSIGGEAHYQCERGYNLKGHQTRTCISKG---QWNGTVPVCIPIDCRSPGNIENGK 917
V + G + C GY L G + C+ G QW+ +P C I C +P I+NG
Sbjct: 176 VPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGI 235
Query: 918 IVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCL---DDGRWSGEEPSC 962
I + SV Y C + +G C D+G WSG P C
Sbjct: 236 IQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPEC 283
Score = 95.9 bits (228), Expect = 7e-19
Identities = 68/249 (27%), Positives = 106/249 (42%), Gaps = 19/249 (7%)
Query: 471 CPDPPAVSNASVTVNGHKA---GSLASYTCENGHI-LSGST-SVTCTLGGAWSGVPPSCK 525
C PP V NA + G + ++ +Y CE + + G SV C G WS + C
Sbjct: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCN 95
Query: 526 YVNCGTPT-IHKGSFVLINGTTTY---GSIAQFTCEPDYWLNGA--EELVCNRDGKWSYD 579
+C PT ++ S T Y G++ ++ C P Y + +L C ++ KWS
Sbjct: 96 R-SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTA 154
Query: 580 IPSCELTSCPEP-EVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDG---EWS 635
+ C+ SCP P E+ +G +TI+F C G+KL G + C G +WS
Sbjct: 155 VEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWS 214
Query: 636 GDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCT---EEF 692
P C I C P + G ++ + Y+C + ++G CT +E
Sbjct: 215 DPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEG 274
Query: 693 QWSDSSPRC 701
+WS P C
Sbjct: 275 EWSGPPPEC 283
Score = 91.5 bits (217), Expect = 2e-17
Identities = 78/271 (28%), Positives = 111/271 (40%), Gaps = 35/271 (12%)
Query: 645 DCGKLPTLPYGTMELLNGTTHL--GSVIQYSCTTNYRLVGPVRRT--CTEEFQWSDSSPR 700
DCG P +P L G T +VI Y C ++ + + + C + QWSD
Sbjct: 35 DCGLPPDVP-NAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEF 93
Query: 701 CEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVI 760
C C P N S I N + +G +V+Y C GY+
Sbjct: 94 CNR-SCEVPTRL---------NSASLKQPYITQ-------NYFPVGTVVEYECRPGYRR- 135
Query: 761 GESLS---TCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENW 817
SLS TC N +WS C+ C NPG I NG++ +P F GAT + C+ +
Sbjct: 136 EPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILF-GATISFSCNTGY 194
Query: 818 ELEGVIRRMCQENGT---WSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQ 874
+L G C +G+ WS P C+EI CP P QI G + Y
Sbjct: 195 KLFGSTSSFCLISGSSVQWSDPLPECREIYCPAP-PQIDNGI-IQGERDHYGYRQSVTYA 252
Query: 875 CERGYNLKGHQTRTCI---SKGQWNGTVPVC 902
C +G+ + G + C +G+W+G P C
Sbjct: 253 CNKGFTMIGEHSIYCTVNNDEGEWSGPPPEC 283
Score = 85.4 bits (202), Expect = 1e-15
Identities = 70/271 (25%), Positives = 111/271 (40%), Gaps = 38/271 (14%)
Query: 528 NCGTPTIHKGSFVLINGTTTY--GSIAQFTCEPDYWLNGAEE--LVCNRDGKWSYDIPSC 583
+CG P + + G T++ ++ + CE + E+ ++C + +WS DI
Sbjct: 35 DCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWS-DIEEF 93
Query: 584 ELTSCPEP-EVPSGGYMEAF---DYY-VHSTINFHCEAGHKLIGE--PNLVCQQDGEWSG 636
SC P + S + + +Y+ V + + + C G++ P L C Q+ +WS
Sbjct: 94 CNRSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWST 153
Query: 637 DSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCT---EEFQ 693
C+ C + G +++ G G+ I +SC T Y+L G C Q
Sbjct: 154 AVEFCKKKSCPNPGEIRNGQIDVPGGIL-FGATISFSCNTGYKLFGSTSSFCLISGSSVQ 212
Query: 694 WSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRC 753
WSD P C EI C P + I+ +R H Y V Y C
Sbjct: 213 WSDPLPECREIYCPAPPQIDNGIIQ---GERDH----------------YGYRQSVTYAC 253
Query: 754 EKGYKVIGESLSTC---EDNGQWSGTTPTCQ 781
KG+ +IGE C D G+WSG P C+
Sbjct: 254 NKGFTMIGEHSIYCTVNNDEGEWSGPPPECR 284
Score = 85.4 bits (202), Expect = 1e-15
Identities = 64/248 (25%), Positives = 101/248 (40%), Gaps = 20/248 (8%)
Query: 413 GLTPIEDGDVALIDNRTTHGARAL--YSCRENFTLVGNPERT--CGDEGIWDGEAPRCLF 468
GL P ++ RT+ + Y C E+F + + + C W C
Sbjct: 37 GLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNR 96
Query: 469 DWCPDPPAVSNAS-----VTVNGHKAGSLASYTCENGHILSGSTS--VTCTLGGAWSGVP 521
C P +++AS +T N G++ Y C G+ S S +TC WS
Sbjct: 97 S-CEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAV 155
Query: 522 PSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDG---KWSY 578
CK +C P + + + G +G+ F+C Y L G+ C G +WS
Sbjct: 156 EFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSD 215
Query: 579 DIPSCELTSCP-EPEVPSGGYMEAFDYY-VHSTINFHCEAGHKLIGEPNLVC---QQDGE 633
+P C CP P++ +G D+Y ++ + C G +IGE ++ C +GE
Sbjct: 216 PLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGE 275
Query: 634 WSGDSPTC 641
WSG P C
Sbjct: 276 WSGPPPEC 283
Score = 78.6 bits (185), Expect = 1e-13
Identities = 65/242 (26%), Positives = 97/242 (40%), Gaps = 21/242 (8%)
Query: 317 GEQNCVVLDGGRGWLWNDVGCNLDYLHWICQYLPPTCGSPDKLLNTTILGNDYDVGSRIV 376
GE++ V+ G W + CN C+ PT + L I N + VG+ +
Sbjct: 74 GEKDSVICLKGSQWSDIEEFCNRS-----CEV--PTRLNSASLKQPYITQNYFPVGTVVE 126
Query: 377 YKCPEGHMLLGDKSRH--CKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRTTHGAR 434
Y+C G+ S C ++ WS A CK +C I +G + + GA
Sbjct: 127 YECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQID-VPGGILFGAT 185
Query: 435 ALYSCRENFTLVGNPERTC---GDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGS 491
+SC + L G+ C G W P C +CP PP + N + G
Sbjct: 186 ISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGY 245
Query: 492 LAS--YTCENGHILSGSTSVTCTLG---GAWSGVPPSCKYVNCGT---PTIHKGSFVLIN 543
S Y C G + G S+ CT+ G WSG PP C+ + + PT+ K + V +
Sbjct: 246 RQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTVQKPTTVNVP 305
Query: 544 GT 545
T
Sbjct: 306 TT 307
Score = 74.9 bits (176), Expect = 1e-12
Identities = 66/267 (24%), Positives = 113/267 (42%), Gaps = 38/267 (14%)
Query: 591 PEVPSGG-YMEAFDYYVHST-INFHCEAGH-KLIGEPN-LVCQQDGEWSGDSPTCEYIDC 646
P+VP+ +E + T I + CE K+ GE + ++C + +WS C C
Sbjct: 40 PDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNR-SC 98
Query: 647 GKLPT-LPYGTME---LLNGTTHLGSVIQYSCTTNYRLVGPV--RRTCTEEFQWSDSSPR 700
++PT L +++ + +G+V++Y C YR + + TC + +WS +
Sbjct: 99 -EVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEF 157
Query: 701 CEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVI 760
C++ C +P + V G GA + + C GYK+
Sbjct: 158 CKKKSCPNPGEIRNGQIDVPGG--------------------ILFGATISFSCNTGYKLF 197
Query: 761 GESLSTCEDNG---QWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENW 817
G + S C +G QWS P C+ + C P +I+NG + + Y + Y C++ +
Sbjct: 198 GSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGF 257
Query: 818 ELEGVIRRMCQEN---GTWSLEPPICK 841
+ G C N G WS PP C+
Sbjct: 258 TMIGEHSIYCTVNNDEGEWSGPPPECR 284
Score = 73.3 bits (172), Expect = 4e-12
Identities = 53/191 (27%), Positives = 82/191 (42%), Gaps = 17/191 (8%)
Query: 784 DCGNPGRIENGKVTLPSNATFYGATAF-YQCDENW-----ELEGVIRRMCQENGTWSLEP 837
DCG P + N + L +F T Y+C+E++ E + VI C + WS
Sbjct: 35 DCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVI---CLKGSQWSDIE 91
Query: 838 PICKEITCPDPSAQIKAGSGLLVVTST-LSIGGEAHYQCERGYNLKGHQTR--TCISKGQ 894
C +C P+ A +T +G Y+C GY + + TC+ +
Sbjct: 92 EFCNR-SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLK 150
Query: 895 WNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDG- 953
W+ V C C +PG I NG+I + G LFG+++ + C + Y+ G CL G
Sbjct: 151 WSTAVEFCKKKSCPNPGEIRNGQIDVP-GGILFGATISFSCNTGYKLFGSTSSFCLISGS 209
Query: 954 --RWSGEEPSC 962
+WS P C
Sbjct: 210 SVQWSDPLPEC 220
Score = 34.3 bits (75), Expect = 2.4
Identities = 17/60 (28%), Positives = 28/60 (46%), Gaps = 5/60 (8%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRG---DWTLEPPFC 58
C +P N ++ +P I+ G + C+ GY+LFG+ C + G W+ P C
Sbjct: 163 CPNPGEIRNGQIDVPG--GILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPEC 220
Score = 32.3 bits (70), Expect = 9.7
Identities = 16/59 (27%), Positives = 29/59 (49%), Gaps = 2/59 (3%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGY-ELFGARQRECTLRG-DWTLEPPFC 58
CG P PNA+ ++ + T+ Y+C+E + ++ G + L+G W+ FC
Sbjct: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFC 94
>AB240567-1|BAE97423.1| 364|Homo sapiens decay-accelerating factor
splicing variant 2 protein.
Length = 364
Score = 97.5 bits (232), Expect = 2e-19
Identities = 65/228 (28%), Positives = 98/228 (42%), Gaps = 17/228 (7%)
Query: 748 LVKYRCEKGY-KVIGESLST-CEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFY 805
++ Y+CE+ + K+ GE S C QWS C C P R+ + + P Y
Sbjct: 60 VITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNR-SCEVPTRLNSASLKQPYITQNY 118
Query: 806 ---GATAFYQCDENWELEGVI--RRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLV 860
G Y+C + E + + C +N WS CK+ +CP+P +I+ +G +
Sbjct: 119 FPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPG-EIR--NGQID 175
Query: 861 VTSTLSIGGEAHYQCERGYNLKGHQTRTCISKG---QWNGTVPVCIPIDCRSPGNIENGK 917
V + G + C GY L G + C+ G QW+ +P C I C +P I+NG
Sbjct: 176 VPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGI 235
Query: 918 IVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCL---DDGRWSGEEPSC 962
I + SV Y C + +G C D+G WSG P C
Sbjct: 236 IQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPEC 283
Score = 95.9 bits (228), Expect = 7e-19
Identities = 68/249 (27%), Positives = 106/249 (42%), Gaps = 19/249 (7%)
Query: 471 CPDPPAVSNASVTVNGHKA---GSLASYTCENGHI-LSGST-SVTCTLGGAWSGVPPSCK 525
C PP V NA + G + ++ +Y CE + + G SV C G WS + C
Sbjct: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCN 95
Query: 526 YVNCGTPT-IHKGSFVLINGTTTY---GSIAQFTCEPDYWLNGA--EELVCNRDGKWSYD 579
+C PT ++ S T Y G++ ++ C P Y + +L C ++ KWS
Sbjct: 96 R-SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTA 154
Query: 580 IPSCELTSCPEP-EVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDG---EWS 635
+ C+ SCP P E+ +G +TI+F C G+KL G + C G +WS
Sbjct: 155 VEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWS 214
Query: 636 GDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCT---EEF 692
P C I C P + G ++ + Y+C + ++G CT +E
Sbjct: 215 DPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEG 274
Query: 693 QWSDSSPRC 701
+WS P C
Sbjct: 275 EWSGPPPEC 283
Score = 91.5 bits (217), Expect = 2e-17
Identities = 78/271 (28%), Positives = 111/271 (40%), Gaps = 35/271 (12%)
Query: 645 DCGKLPTLPYGTMELLNGTTHL--GSVIQYSCTTNYRLVGPVRRT--CTEEFQWSDSSPR 700
DCG P +P L G T +VI Y C ++ + + + C + QWSD
Sbjct: 35 DCGLPPDVP-NAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEF 93
Query: 701 CEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVI 760
C C P N S I N + +G +V+Y C GY+
Sbjct: 94 CNR-SCEVPTRL---------NSASLKQPYITQ-------NYFPVGTVVEYECRPGYRR- 135
Query: 761 GESLS---TCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENW 817
SLS TC N +WS C+ C NPG I NG++ +P F GAT + C+ +
Sbjct: 136 EPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILF-GATISFSCNTGY 194
Query: 818 ELEGVIRRMCQENGT---WSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQ 874
+L G C +G+ WS P C+EI CP P QI G + Y
Sbjct: 195 KLFGSTSSFCLISGSSVQWSDPLPECREIYCPAP-PQIDNGI-IQGERDHYGYRQSVTYA 252
Query: 875 CERGYNLKGHQTRTCI---SKGQWNGTVPVC 902
C +G+ + G + C +G+W+G P C
Sbjct: 253 CNKGFTMIGEHSIYCTVNNDEGEWSGPPPEC 283
Score = 85.4 bits (202), Expect = 1e-15
Identities = 70/271 (25%), Positives = 111/271 (40%), Gaps = 38/271 (14%)
Query: 528 NCGTPTIHKGSFVLINGTTTY--GSIAQFTCEPDYWLNGAEE--LVCNRDGKWSYDIPSC 583
+CG P + + G T++ ++ + CE + E+ ++C + +WS DI
Sbjct: 35 DCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWS-DIEEF 93
Query: 584 ELTSCPEP-EVPSGGYMEAF---DYY-VHSTINFHCEAGHKLIGE--PNLVCQQDGEWSG 636
SC P + S + + +Y+ V + + + C G++ P L C Q+ +WS
Sbjct: 94 CNRSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWST 153
Query: 637 DSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCT---EEFQ 693
C+ C + G +++ G G+ I +SC T Y+L G C Q
Sbjct: 154 AVEFCKKKSCPNPGEIRNGQIDVPGGIL-FGATISFSCNTGYKLFGSTSSFCLISGSSVQ 212
Query: 694 WSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRC 753
WSD P C EI C P + I+ +R H Y V Y C
Sbjct: 213 WSDPLPECREIYCPAPPQIDNGIIQ---GERDH----------------YGYRQSVTYAC 253
Query: 754 EKGYKVIGESLSTC---EDNGQWSGTTPTCQ 781
KG+ +IGE C D G+WSG P C+
Sbjct: 254 NKGFTMIGEHSIYCTVNNDEGEWSGPPPECR 284
Score = 85.4 bits (202), Expect = 1e-15
Identities = 64/248 (25%), Positives = 101/248 (40%), Gaps = 20/248 (8%)
Query: 413 GLTPIEDGDVALIDNRTTHGARAL--YSCRENFTLVGNPERT--CGDEGIWDGEAPRCLF 468
GL P ++ RT+ + Y C E+F + + + C W C
Sbjct: 37 GLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNR 96
Query: 469 DWCPDPPAVSNAS-----VTVNGHKAGSLASYTCENGHILSGSTS--VTCTLGGAWSGVP 521
C P +++AS +T N G++ Y C G+ S S +TC WS
Sbjct: 97 S-CEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAV 155
Query: 522 PSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDG---KWSY 578
CK +C P + + + G +G+ F+C Y L G+ C G +WS
Sbjct: 156 EFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSD 215
Query: 579 DIPSCELTSCP-EPEVPSGGYMEAFDYY-VHSTINFHCEAGHKLIGEPNLVC---QQDGE 633
+P C CP P++ +G D+Y ++ + C G +IGE ++ C +GE
Sbjct: 216 PLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGE 275
Query: 634 WSGDSPTC 641
WSG P C
Sbjct: 276 WSGPPPEC 283
Score = 78.6 bits (185), Expect = 1e-13
Identities = 65/242 (26%), Positives = 97/242 (40%), Gaps = 21/242 (8%)
Query: 317 GEQNCVVLDGGRGWLWNDVGCNLDYLHWICQYLPPTCGSPDKLLNTTILGNDYDVGSRIV 376
GE++ V+ G W + CN C+ PT + L I N + VG+ +
Sbjct: 74 GEKDSVICLKGSQWSDIEEFCNRS-----CEV--PTRLNSASLKQPYITQNYFPVGTVVE 126
Query: 377 YKCPEGHMLLGDKSRH--CKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRTTHGAR 434
Y+C G+ S C ++ WS A CK +C I +G + + GA
Sbjct: 127 YECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQID-VPGGILFGAT 185
Query: 435 ALYSCRENFTLVGNPERTC---GDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGS 491
+SC + L G+ C G W P C +CP PP + N + G
Sbjct: 186 ISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGY 245
Query: 492 LAS--YTCENGHILSGSTSVTCTLG---GAWSGVPPSCKYVNCGT---PTIHKGSFVLIN 543
S Y C G + G S+ CT+ G WSG PP C+ + + PT+ K + V +
Sbjct: 246 RQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTVQKPTTVNVP 305
Query: 544 GT 545
T
Sbjct: 306 TT 307
Score = 74.9 bits (176), Expect = 1e-12
Identities = 66/267 (24%), Positives = 113/267 (42%), Gaps = 38/267 (14%)
Query: 591 PEVPSGG-YMEAFDYYVHST-INFHCEAGH-KLIGEPN-LVCQQDGEWSGDSPTCEYIDC 646
P+VP+ +E + T I + CE K+ GE + ++C + +WS C C
Sbjct: 40 PDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNR-SC 98
Query: 647 GKLPT-LPYGTME---LLNGTTHLGSVIQYSCTTNYRLVGPV--RRTCTEEFQWSDSSPR 700
++PT L +++ + +G+V++Y C YR + + TC + +WS +
Sbjct: 99 -EVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEF 157
Query: 701 CEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVI 760
C++ C +P + V G GA + + C GYK+
Sbjct: 158 CKKKSCPNPGEIRNGQIDVPGG--------------------ILFGATISFSCNTGYKLF 197
Query: 761 GESLSTCEDNG---QWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENW 817
G + S C +G QWS P C+ + C P +I+NG + + Y + Y C++ +
Sbjct: 198 GSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGF 257
Query: 818 ELEGVIRRMCQEN---GTWSLEPPICK 841
+ G C N G WS PP C+
Sbjct: 258 TMIGEHSIYCTVNNDEGEWSGPPPECR 284
Score = 73.3 bits (172), Expect = 4e-12
Identities = 53/191 (27%), Positives = 82/191 (42%), Gaps = 17/191 (8%)
Query: 784 DCGNPGRIENGKVTLPSNATFYGATAF-YQCDENW-----ELEGVIRRMCQENGTWSLEP 837
DCG P + N + L +F T Y+C+E++ E + VI C + WS
Sbjct: 35 DCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVI---CLKGSQWSDIE 91
Query: 838 PICKEITCPDPSAQIKAGSGLLVVTST-LSIGGEAHYQCERGYNLKGHQTR--TCISKGQ 894
C +C P+ A +T +G Y+C GY + + TC+ +
Sbjct: 92 EFCNR-SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLK 150
Query: 895 WNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDG- 953
W+ V C C +PG I NG+I + G LFG+++ + C + Y+ G CL G
Sbjct: 151 WSTAVEFCKKKSCPNPGEIRNGQIDVP-GGILFGATISFSCNTGYKLFGSTSSFCLISGS 209
Query: 954 --RWSGEEPSC 962
+WS P C
Sbjct: 210 SVQWSDPLPEC 220
Score = 34.3 bits (75), Expect = 2.4
Identities = 17/60 (28%), Positives = 28/60 (46%), Gaps = 5/60 (8%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRG---DWTLEPPFC 58
C +P N ++ +P I+ G + C+ GY+LFG+ C + G W+ P C
Sbjct: 163 CPNPGEIRNGQIDVPG--GILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPEC 220
Score = 32.3 bits (70), Expect = 9.7
Identities = 16/59 (27%), Positives = 29/59 (49%), Gaps = 2/59 (3%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGY-ELFGARQRECTLRG-DWTLEPPFC 58
CG P PNA+ ++ + T+ Y+C+E + ++ G + L+G W+ FC
Sbjct: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFC 94
>AB240566-1|BAE97422.1| 439|Homo sapiens decay-accelerating factor
splicing variant 1 protein.
Length = 439
Score = 97.5 bits (232), Expect = 2e-19
Identities = 65/228 (28%), Positives = 98/228 (42%), Gaps = 17/228 (7%)
Query: 748 LVKYRCEKGY-KVIGESLST-CEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFY 805
++ Y+CE+ + K+ GE S C QWS C C P R+ + + P Y
Sbjct: 60 VITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNR-SCEVPTRLNSASLKQPYITQNY 118
Query: 806 ---GATAFYQCDENWELEGVI--RRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLV 860
G Y+C + E + + C +N WS CK+ +CP+P +I+ +G +
Sbjct: 119 FPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPG-EIR--NGQID 175
Query: 861 VTSTLSIGGEAHYQCERGYNLKGHQTRTCISKG---QWNGTVPVCIPIDCRSPGNIENGK 917
V + G + C GY L G + C+ G QW+ +P C I C +P I+NG
Sbjct: 176 VPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGI 235
Query: 918 IVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCL---DDGRWSGEEPSC 962
I + SV Y C + +G C D+G WSG P C
Sbjct: 236 IQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPEC 283
Score = 95.9 bits (228), Expect = 7e-19
Identities = 68/249 (27%), Positives = 106/249 (42%), Gaps = 19/249 (7%)
Query: 471 CPDPPAVSNASVTVNGHKA---GSLASYTCENGHI-LSGST-SVTCTLGGAWSGVPPSCK 525
C PP V NA + G + ++ +Y CE + + G SV C G WS + C
Sbjct: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCN 95
Query: 526 YVNCGTPT-IHKGSFVLINGTTTY---GSIAQFTCEPDYWLNGA--EELVCNRDGKWSYD 579
+C PT ++ S T Y G++ ++ C P Y + +L C ++ KWS
Sbjct: 96 R-SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTA 154
Query: 580 IPSCELTSCPEP-EVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDG---EWS 635
+ C+ SCP P E+ +G +TI+F C G+KL G + C G +WS
Sbjct: 155 VEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWS 214
Query: 636 GDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCT---EEF 692
P C I C P + G ++ + Y+C + ++G CT +E
Sbjct: 215 DPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEG 274
Query: 693 QWSDSSPRC 701
+WS P C
Sbjct: 275 EWSGPPPEC 283
Score = 91.5 bits (217), Expect = 2e-17
Identities = 78/271 (28%), Positives = 111/271 (40%), Gaps = 35/271 (12%)
Query: 645 DCGKLPTLPYGTMELLNGTTHL--GSVIQYSCTTNYRLVGPVRRT--CTEEFQWSDSSPR 700
DCG P +P L G T +VI Y C ++ + + + C + QWSD
Sbjct: 35 DCGLPPDVP-NAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEF 93
Query: 701 CEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVI 760
C C P N S I N + +G +V+Y C GY+
Sbjct: 94 CNR-SCEVPTRL---------NSASLKQPYITQ-------NYFPVGTVVEYECRPGYRR- 135
Query: 761 GESLS---TCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENW 817
SLS TC N +WS C+ C NPG I NG++ +P F GAT + C+ +
Sbjct: 136 EPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILF-GATISFSCNTGY 194
Query: 818 ELEGVIRRMCQENGT---WSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQ 874
+L G C +G+ WS P C+EI CP P QI G + Y
Sbjct: 195 KLFGSTSSFCLISGSSVQWSDPLPECREIYCPAP-PQIDNGI-IQGERDHYGYRQSVTYA 252
Query: 875 CERGYNLKGHQTRTCI---SKGQWNGTVPVC 902
C +G+ + G + C +G+W+G P C
Sbjct: 253 CNKGFTMIGEHSIYCTVNNDEGEWSGPPPEC 283
Score = 85.4 bits (202), Expect = 1e-15
Identities = 70/271 (25%), Positives = 111/271 (40%), Gaps = 38/271 (14%)
Query: 528 NCGTPTIHKGSFVLINGTTTY--GSIAQFTCEPDYWLNGAEE--LVCNRDGKWSYDIPSC 583
+CG P + + G T++ ++ + CE + E+ ++C + +WS DI
Sbjct: 35 DCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWS-DIEEF 93
Query: 584 ELTSCPEP-EVPSGGYMEAF---DYY-VHSTINFHCEAGHKLIGE--PNLVCQQDGEWSG 636
SC P + S + + +Y+ V + + + C G++ P L C Q+ +WS
Sbjct: 94 CNRSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWST 153
Query: 637 DSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCT---EEFQ 693
C+ C + G +++ G G+ I +SC T Y+L G C Q
Sbjct: 154 AVEFCKKKSCPNPGEIRNGQIDVPGGIL-FGATISFSCNTGYKLFGSTSSFCLISGSSVQ 212
Query: 694 WSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRC 753
WSD P C EI C P + I+ +R H Y V Y C
Sbjct: 213 WSDPLPECREIYCPAPPQIDNGIIQ---GERDH----------------YGYRQSVTYAC 253
Query: 754 EKGYKVIGESLSTC---EDNGQWSGTTPTCQ 781
KG+ +IGE C D G+WSG P C+
Sbjct: 254 NKGFTMIGEHSIYCTVNNDEGEWSGPPPECR 284
Score = 85.4 bits (202), Expect = 1e-15
Identities = 64/248 (25%), Positives = 101/248 (40%), Gaps = 20/248 (8%)
Query: 413 GLTPIEDGDVALIDNRTTHGARAL--YSCRENFTLVGNPERT--CGDEGIWDGEAPRCLF 468
GL P ++ RT+ + Y C E+F + + + C W C
Sbjct: 37 GLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNR 96
Query: 469 DWCPDPPAVSNAS-----VTVNGHKAGSLASYTCENGHILSGSTS--VTCTLGGAWSGVP 521
C P +++AS +T N G++ Y C G+ S S +TC WS
Sbjct: 97 S-CEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAV 155
Query: 522 PSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDG---KWSY 578
CK +C P + + + G +G+ F+C Y L G+ C G +WS
Sbjct: 156 EFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSD 215
Query: 579 DIPSCELTSCP-EPEVPSGGYMEAFDYY-VHSTINFHCEAGHKLIGEPNLVC---QQDGE 633
+P C CP P++ +G D+Y ++ + C G +IGE ++ C +GE
Sbjct: 216 PLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGE 275
Query: 634 WSGDSPTC 641
WSG P C
Sbjct: 276 WSGPPPEC 283
Score = 78.6 bits (185), Expect = 1e-13
Identities = 65/242 (26%), Positives = 97/242 (40%), Gaps = 21/242 (8%)
Query: 317 GEQNCVVLDGGRGWLWNDVGCNLDYLHWICQYLPPTCGSPDKLLNTTILGNDYDVGSRIV 376
GE++ V+ G W + CN C+ PT + L I N + VG+ +
Sbjct: 74 GEKDSVICLKGSQWSDIEEFCNRS-----CEV--PTRLNSASLKQPYITQNYFPVGTVVE 126
Query: 377 YKCPEGHMLLGDKSRH--CKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRTTHGAR 434
Y+C G+ S C ++ WS A CK +C I +G + + GA
Sbjct: 127 YECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQID-VPGGILFGAT 185
Query: 435 ALYSCRENFTLVGNPERTC---GDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGS 491
+SC + L G+ C G W P C +CP PP + N + G
Sbjct: 186 ISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGY 245
Query: 492 LAS--YTCENGHILSGSTSVTCTLG---GAWSGVPPSCKYVNCGT---PTIHKGSFVLIN 543
S Y C G + G S+ CT+ G WSG PP C+ + + PT+ K + V +
Sbjct: 246 RQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTVQKPTTVNVP 305
Query: 544 GT 545
T
Sbjct: 306 TT 307
Score = 74.9 bits (176), Expect = 1e-12
Identities = 66/267 (24%), Positives = 113/267 (42%), Gaps = 38/267 (14%)
Query: 591 PEVPSGG-YMEAFDYYVHST-INFHCEAGH-KLIGEPN-LVCQQDGEWSGDSPTCEYIDC 646
P+VP+ +E + T I + CE K+ GE + ++C + +WS C C
Sbjct: 40 PDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNR-SC 98
Query: 647 GKLPT-LPYGTME---LLNGTTHLGSVIQYSCTTNYRLVGPV--RRTCTEEFQWSDSSPR 700
++PT L +++ + +G+V++Y C YR + + TC + +WS +
Sbjct: 99 -EVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEF 157
Query: 701 CEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVI 760
C++ C +P + V G GA + + C GYK+
Sbjct: 158 CKKKSCPNPGEIRNGQIDVPGG--------------------ILFGATISFSCNTGYKLF 197
Query: 761 GESLSTCEDNG---QWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENW 817
G + S C +G QWS P C+ + C P +I+NG + + Y + Y C++ +
Sbjct: 198 GSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGF 257
Query: 818 ELEGVIRRMCQEN---GTWSLEPPICK 841
+ G C N G WS PP C+
Sbjct: 258 TMIGEHSIYCTVNNDEGEWSGPPPECR 284
Score = 73.3 bits (172), Expect = 4e-12
Identities = 53/191 (27%), Positives = 82/191 (42%), Gaps = 17/191 (8%)
Query: 784 DCGNPGRIENGKVTLPSNATFYGATAF-YQCDENW-----ELEGVIRRMCQENGTWSLEP 837
DCG P + N + L +F T Y+C+E++ E + VI C + WS
Sbjct: 35 DCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVI---CLKGSQWSDIE 91
Query: 838 PICKEITCPDPSAQIKAGSGLLVVTST-LSIGGEAHYQCERGYNLKGHQTR--TCISKGQ 894
C +C P+ A +T +G Y+C GY + + TC+ +
Sbjct: 92 EFCNR-SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLK 150
Query: 895 WNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDG- 953
W+ V C C +PG I NG+I + G LFG+++ + C + Y+ G CL G
Sbjct: 151 WSTAVEFCKKKSCPNPGEIRNGQIDVP-GGILFGATISFSCNTGYKLFGSTSSFCLISGS 209
Query: 954 --RWSGEEPSC 962
+WS P C
Sbjct: 210 SVQWSDPLPEC 220
Score = 34.3 bits (75), Expect = 2.4
Identities = 17/60 (28%), Positives = 28/60 (46%), Gaps = 5/60 (8%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRG---DWTLEPPFC 58
C +P N ++ +P I+ G + C+ GY+LFG+ C + G W+ P C
Sbjct: 163 CPNPGEIRNGQIDVPG--GILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPEC 220
Score = 32.3 bits (70), Expect = 9.7
Identities = 16/59 (27%), Positives = 29/59 (49%), Gaps = 2/59 (3%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGY-ELFGARQRECTLRG-DWTLEPPFC 58
CG P PNA+ ++ + T+ Y+C+E + ++ G + L+G W+ FC
Sbjct: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFC 94
>Y11493-1|CAA72279.1| 345|Homo sapiens beta-2-glycoprotein I
protein.
Length = 345
Score = 97.1 bits (231), Expect = 3e-19
Identities = 58/220 (26%), Positives = 88/220 (40%), Gaps = 11/220 (5%)
Query: 432 GARALYSCRENFTLVGNPER-TCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAG 490
G YSC+ + G + C G+W +C CP + N +V +
Sbjct: 44 GEEITYSCKPGYVSRGGMRKFICPLTGLWPINTLKCTPRVCPFAGILENGAVRYTTFEYP 103
Query: 491 SLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTIHKGSFVLI-----NGT 545
+ S++C G L+G+ S CT G WS P C + C P+I + + +
Sbjct: 104 NTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAPIICPPPSIPTFATLRVYKPSAGNN 163
Query: 546 TTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGG---YMEAF 602
+ Y A F C P + + G + + C G W+ +P C CP P P G Y
Sbjct: 164 SLYRDTAVFECLPQHAMFGNDTITCTTHGNWT-KLPECREVKCPFPSRPDNGFVNYPAKP 222
Query: 603 DYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCE 642
Y F C G+ L G + C + G WS P+C+
Sbjct: 223 TLYYKDKATFGCHDGYSLDGPEEIECTKLGNWSA-MPSCK 261
Score = 92.7 bits (220), Expect = 6e-18
Identities = 64/251 (25%), Positives = 100/251 (39%), Gaps = 16/251 (6%)
Query: 471 CPDPPAVSNASVTV--NGHKAGSLASYTCENGHILSGST-SVTCTLGGAWSGVPPSCKYV 527
CP P + ++V ++ G +Y+C+ G++ G C L G W C
Sbjct: 23 CPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYVSRGGMRKFICPLTGLWPINTLKCTPR 82
Query: 528 NCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTS 587
C I + V T Y + F+C ++LNGA+ C +GKWS ++P C
Sbjct: 83 VCPFAGILENGAVRYT-TFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAPII 141
Query: 588 CPEPEVPSGGYMEAF------DYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTC 641
CP P +P+ + + + T F C H + G + C G W+ P C
Sbjct: 142 CPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWT-KLPEC 200
Query: 642 EYIDCGKLPTLP-YGTMEL-LNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSP 699
+ C P+ P G + T + + C Y L GP CT+ WS + P
Sbjct: 201 REVKC-PFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSLDGPEEIECTKLGNWS-AMP 258
Query: 700 RCEEIRCSDPI 710
C + C P+
Sbjct: 259 SC-KASCKVPV 268
Score = 90.2 bits (214), Expect = 3e-17
Identities = 68/237 (28%), Positives = 93/237 (39%), Gaps = 10/237 (4%)
Query: 743 YRIGALVKYRCEKGYKVIGESLS-TCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSN 801
Y G + Y C+ GY G C G W T C C G +ENG V
Sbjct: 41 YEPGEEITYSCKPGYVSRGGMRKFICPLTGLWPINTLKCTPRVCPFAGILENGAVRY--- 97
Query: 802 ATF-YGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLV 860
TF Y T + C+ + L G C E G WS E P+C I CP PS A +
Sbjct: 98 TTFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAPIICPPPSIPTFATLRVYK 157
Query: 861 VT--STLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKI 918
+ + A ++C + + G+ T TC + G W +P C + C P +NG +
Sbjct: 158 PSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWT-KLPECREVKCPFPSRPDNGFV 216
Query: 919 VISNGSTL-FGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCELATNEAVDSGT 974
TL + + C Y GP +C G WS PSC+ + V T
Sbjct: 217 NYPAKPTLYYKDKATFGCHDGYSLDGPEEIECTKLGNWSA-MPSCKASCKVPVKKAT 272
Score = 84.2 bits (199), Expect = 2e-15
Identities = 71/266 (26%), Positives = 109/266 (40%), Gaps = 24/266 (9%)
Query: 587 SCPEPE-VPSGGYMEAFDYYVHST-INFHCEAGH-KLIGEPNLVCQQDGEWSGDSPTCEY 643
+CP+P+ +P + +Y I + C+ G+ G +C G W ++ C
Sbjct: 22 TCPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYVSRGGMRKFICPLTGLWPINTLKCTP 81
Query: 644 IDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEE 703
C L G + T + I +SC T + L G CTEE +WS P C
Sbjct: 82 RVCPFAGILENGAVRYT--TFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAP 139
Query: 704 IRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGES 763
I C P + + + V S G+ + YR A+ + C + + G
Sbjct: 140 IICPPPSIPTFATLRV--YKPSAGN-----------NSLYRDTAV--FECLPQHAMFGND 184
Query: 764 LSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNAT-FYGATAFYQCDENWELEGV 822
TC +G W+ P C+ V C P R +NG V P+ T +Y A + C + + L+G
Sbjct: 185 TITCTTHGNWT-KLPECREVKCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSLDGP 243
Query: 823 IRRMCQENGTWSLEPPICKEITCPDP 848
C + G WS P CK +C P
Sbjct: 244 EEIECTKLGNWSAMPS-CK-ASCKVP 267
Score = 77.4 bits (182), Expect = 3e-13
Identities = 68/270 (25%), Positives = 103/270 (38%), Gaps = 30/270 (11%)
Query: 646 CGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRR-TCTEEFQWSDSSPRCEEI 704
C K LP+ T+ L G I YSC Y G +R+ C W ++ +C
Sbjct: 23 CPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYVSRGGMRKFICPLTGLWPINTLKCTPR 82
Query: 705 RCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESL 764
C + E V T T+ + + C G+ + G
Sbjct: 83 VCPFAGILENGAVRYT---------------------TFEYPNTISFSCNTGFYLNGADS 121
Query: 765 STCEDNGQWSGTTPTCQYVDCGNPG--RIENGKVTLPS--NATFYGATAFYQCDENWELE 820
+ C + G+WS P C + C P +V PS N + Y TA ++C +
Sbjct: 122 AKCTEEGKWSPELPVCAPIICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMF 181
Query: 821 GVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYN 880
G C +G W+ + P C+E+ CP PS + G TL +A + C GY+
Sbjct: 182 GNDTITCTTHGNWT-KLPECREVKCPFPS-RPDNGFVNYPAKPTLYYKDKATFGCHDGYS 239
Query: 881 LKGHQTRTCISKGQWNGTVPVCIPIDCRSP 910
L G + C G W+ +P C C+ P
Sbjct: 240 LDGPEEIECTKLGNWS-AMPSC-KASCKVP 267
Score = 67.3 bits (157), Expect = 3e-10
Identities = 49/190 (25%), Positives = 73/190 (38%), Gaps = 10/190 (5%)
Query: 350 PPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYV 409
P C L N + ++ + I + C G L G S C ++G WS P C +
Sbjct: 81 PRVCPFAGILENGAVRYTTFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAPI 140
Query: 410 NCGGLTPIEDGDVAL----IDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPR 465
C + + + N + + A++ C + GN TC G W + P
Sbjct: 141 ICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWT-KLPE 199
Query: 466 CLFDWCPDPPAVSNASVTVNGHKA---GSLASYTCENGHILSGSTSVTCTLGGAWSGVPP 522
C CP P N V A++ C +G+ L G + CT G WS + P
Sbjct: 200 CREVKCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSLDGPEEIECTKLGNWSAM-P 258
Query: 523 SCKYVNCGTP 532
SCK +C P
Sbjct: 259 SCK-ASCKVP 267
Score = 43.6 bits (98), Expect = 0.004
Identities = 22/77 (28%), Positives = 36/77 (46%), Gaps = 3/77 (3%)
Query: 1 RCGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGT 60
+C P+ P N V+ P + + A + C +GY L G + ECT G+W+ P
Sbjct: 204 KCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSLDGPEEIECTKLGNWSAMP---SC 260
Query: 61 NVAFRKPANQSTTVRGG 77
+ + P ++T V G
Sbjct: 261 KASCKVPVKKATVVYQG 277
Score = 32.7 bits (71), Expect = 7.4
Identities = 20/57 (35%), Positives = 28/57 (49%), Gaps = 3/57 (5%)
Query: 2 CGHPAVPPNA--RVSIPNE-ENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEP 55
C P++P A RV P+ N + AV+EC + +FG CT G+WT P
Sbjct: 142 CPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWTKLP 198
Score = 32.3 bits (70), Expect = 9.7
Identities = 12/30 (40%), Positives = 17/30 (56%)
Query: 29 YECDEGYELFGARQRECTLRGDWTLEPPFC 58
+ C+ G+ L GA +CT G W+ E P C
Sbjct: 108 FSCNTGFYLNGADSAKCTEEGKWSPELPVC 137
>X57847-1|CAA40977.1| 345|Homo sapiens Apolipoprotein H
(beta2-glycoprotein I) protein.
Length = 345
Score = 97.1 bits (231), Expect = 3e-19
Identities = 58/220 (26%), Positives = 88/220 (40%), Gaps = 11/220 (5%)
Query: 432 GARALYSCRENFTLVGNPER-TCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAG 490
G YSC+ + G + C G+W +C CP + N +V +
Sbjct: 44 GEEITYSCKPGYVSRGGMRKFICPLTGLWPINTLKCTPRVCPFAGILENGAVRYTTFEYP 103
Query: 491 SLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTIHKGSFVLI-----NGT 545
+ S++C G L+G+ S CT G WS P C + C P+I + + +
Sbjct: 104 NTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAPIICPPPSIPTFATLRVYKPSAGNN 163
Query: 546 TTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGG---YMEAF 602
+ Y A F C P + + G + + C G W+ +P C CP P P G Y
Sbjct: 164 SLYRDTAVFECLPQHAMFGNDTITCTTHGNWT-KLPECREVKCPFPSRPDNGFVNYPAKP 222
Query: 603 DYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCE 642
Y F C G+ L G + C + G WS P+C+
Sbjct: 223 TLYYKDKATFGCHDGYSLDGPEEIECTKLGNWSA-MPSCK 261
Score = 92.7 bits (220), Expect = 6e-18
Identities = 64/251 (25%), Positives = 100/251 (39%), Gaps = 16/251 (6%)
Query: 471 CPDPPAVSNASVTV--NGHKAGSLASYTCENGHILSGST-SVTCTLGGAWSGVPPSCKYV 527
CP P + ++V ++ G +Y+C+ G++ G C L G W C
Sbjct: 23 CPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYVSRGGMRKFICPLTGLWPINTLKCTPR 82
Query: 528 NCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTS 587
C I + V T Y + F+C ++LNGA+ C +GKWS ++P C
Sbjct: 83 VCPFAGILENGAVRYT-TFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAPII 141
Query: 588 CPEPEVPSGGYMEAF------DYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTC 641
CP P +P+ + + + T F C H + G + C G W+ P C
Sbjct: 142 CPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWT-KLPEC 200
Query: 642 EYIDCGKLPTLP-YGTMEL-LNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSP 699
+ C P+ P G + T + + C Y L GP CT+ WS + P
Sbjct: 201 REVKC-PFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSLDGPEEIECTKLGNWS-AMP 258
Query: 700 RCEEIRCSDPI 710
C + C P+
Sbjct: 259 SC-KASCKVPV 268
Score = 90.2 bits (214), Expect = 3e-17
Identities = 68/237 (28%), Positives = 93/237 (39%), Gaps = 10/237 (4%)
Query: 743 YRIGALVKYRCEKGYKVIGESLS-TCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSN 801
Y G + Y C+ GY G C G W T C C G +ENG V
Sbjct: 41 YEPGEEITYSCKPGYVSRGGMRKFICPLTGLWPINTLKCTPRVCPFAGILENGAVRY--- 97
Query: 802 ATF-YGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLV 860
TF Y T + C+ + L G C E G WS E P+C I CP PS A +
Sbjct: 98 TTFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAPIICPPPSIPTFATLRVYK 157
Query: 861 VT--STLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKI 918
+ + A ++C + + G+ T TC + G W +P C + C P +NG +
Sbjct: 158 PSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWT-KLPECREVKCPFPSRPDNGFV 216
Query: 919 VISNGSTL-FGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCELATNEAVDSGT 974
TL + + C Y GP +C G WS PSC+ + V T
Sbjct: 217 NYPAKPTLYYKDKATFGCHDGYSLDGPEEIECTKLGNWSA-MPSCKASCKVPVKKAT 272
Score = 84.2 bits (199), Expect = 2e-15
Identities = 71/266 (26%), Positives = 109/266 (40%), Gaps = 24/266 (9%)
Query: 587 SCPEPE-VPSGGYMEAFDYYVHST-INFHCEAGH-KLIGEPNLVCQQDGEWSGDSPTCEY 643
+CP+P+ +P + +Y I + C+ G+ G +C G W ++ C
Sbjct: 22 TCPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYVSRGGMRKFICPLTGLWPINTLKCTP 81
Query: 644 IDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEE 703
C L G + T + I +SC T + L G CTEE +WS P C
Sbjct: 82 RVCPFAGILENGAVRYT--TFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAP 139
Query: 704 IRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGES 763
I C P + + + V S G+ + YR A+ + C + + G
Sbjct: 140 IICPPPSIPTFATLRV--YKPSAGN-----------NSLYRDTAV--FECLPQHAMFGND 184
Query: 764 LSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNAT-FYGATAFYQCDENWELEGV 822
TC +G W+ P C+ V C P R +NG V P+ T +Y A + C + + L+G
Sbjct: 185 TITCTTHGNWT-KLPECREVKCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSLDGP 243
Query: 823 IRRMCQENGTWSLEPPICKEITCPDP 848
C + G WS P CK +C P
Sbjct: 244 EEIECTKLGNWSAMPS-CK-ASCKVP 267
Score = 77.4 bits (182), Expect = 3e-13
Identities = 68/270 (25%), Positives = 103/270 (38%), Gaps = 30/270 (11%)
Query: 646 CGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRR-TCTEEFQWSDSSPRCEEI 704
C K LP+ T+ L G I YSC Y G +R+ C W ++ +C
Sbjct: 23 CPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYVSRGGMRKFICPLTGLWPINTLKCTPR 82
Query: 705 RCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESL 764
C + E V T T+ + + C G+ + G
Sbjct: 83 VCPFAGILENGAVRYT---------------------TFEYPNTISFSCNTGFYLNGADS 121
Query: 765 STCEDNGQWSGTTPTCQYVDCGNPG--RIENGKVTLPS--NATFYGATAFYQCDENWELE 820
+ C + G+WS P C + C P +V PS N + Y TA ++C +
Sbjct: 122 AKCTEEGKWSPELPVCAPIICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMF 181
Query: 821 GVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYN 880
G C +G W+ + P C+E+ CP PS + G TL +A + C GY+
Sbjct: 182 GNDTITCTTHGNWT-KLPECREVKCPFPS-RPDNGFVNYPAKPTLYYKDKATFGCHDGYS 239
Query: 881 LKGHQTRTCISKGQWNGTVPVCIPIDCRSP 910
L G + C G W+ +P C C+ P
Sbjct: 240 LDGPEEIECTKLGNWS-AMPSC-KASCKVP 267
Score = 67.3 bits (157), Expect = 3e-10
Identities = 49/190 (25%), Positives = 73/190 (38%), Gaps = 10/190 (5%)
Query: 350 PPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYV 409
P C L N + ++ + I + C G L G S C ++G WS P C +
Sbjct: 81 PRVCPFAGILENGAVRYTTFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAPI 140
Query: 410 NCGGLTPIEDGDVAL----IDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPR 465
C + + + N + + A++ C + GN TC G W + P
Sbjct: 141 ICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWT-KLPE 199
Query: 466 CLFDWCPDPPAVSNASVTVNGHKA---GSLASYTCENGHILSGSTSVTCTLGGAWSGVPP 522
C CP P N V A++ C +G+ L G + CT G WS + P
Sbjct: 200 CREVKCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSLDGPEEIECTKLGNWSAM-P 258
Query: 523 SCKYVNCGTP 532
SCK +C P
Sbjct: 259 SCK-ASCKVP 267
Score = 43.6 bits (98), Expect = 0.004
Identities = 22/77 (28%), Positives = 36/77 (46%), Gaps = 3/77 (3%)
Query: 1 RCGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGT 60
+C P+ P N V+ P + + A + C +GY L G + ECT G+W+ P
Sbjct: 204 KCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSLDGPEEIECTKLGNWSAMP---SC 260
Query: 61 NVAFRKPANQSTTVRGG 77
+ + P ++T V G
Sbjct: 261 KASCKVPVKKATVVYQG 277
Score = 32.7 bits (71), Expect = 7.4
Identities = 20/57 (35%), Positives = 28/57 (49%), Gaps = 3/57 (5%)
Query: 2 CGHPAVPPNA--RVSIPNE-ENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEP 55
C P++P A RV P+ N + AV+EC + +FG CT G+WT P
Sbjct: 142 CPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWTKLP 198
Score = 32.3 bits (70), Expect = 9.7
Identities = 12/30 (40%), Positives = 17/30 (56%)
Query: 29 YECDEGYELFGARQRECTLRGDWTLEPPFC 58
+ C+ G+ L GA +CT G W+ E P C
Sbjct: 108 FSCNTGFYLNGADSAKCTEEGKWSPELPVC 137
>U88576-1|AAB48622.1| 347|Homo sapiens decay-acceleration factor
protein.
Length = 347
Score = 97.1 bits (231), Expect = 3e-19
Identities = 65/228 (28%), Positives = 98/228 (42%), Gaps = 17/228 (7%)
Query: 748 LVKYRCEKGY-KVIGESLST-CEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFY 805
++ Y+CE+ + K+ GE S C QWS C C P R+ + + P Y
Sbjct: 26 VITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNR-SCEVPTRLNSASLKQPYITQNY 84
Query: 806 ---GATAFYQCDENWELEGVI--RRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLV 860
G Y+C + E + + C +N WS CK+ +CP+P +I+ +G +
Sbjct: 85 FPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPG-EIR--NGQID 141
Query: 861 VTSTLSIGGEAHYQCERGYNLKGHQTRTCISKG---QWNGTVPVCIPIDCRSPGNIENGK 917
V + G + C GY L G + C+ G QW+ +P C I C +P I+NG
Sbjct: 142 VPGGILFGATITFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGI 201
Query: 918 IVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCL---DDGRWSGEEPSC 962
I + SV Y C + +G C D+G WSG P C
Sbjct: 202 IQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPEC 249
Score = 95.5 bits (227), Expect = 9e-19
Identities = 68/249 (27%), Positives = 105/249 (42%), Gaps = 19/249 (7%)
Query: 471 CPDPPAVSNASVTVNGHKA---GSLASYTCENGHI-LSGST-SVTCTLGGAWSGVPPSCK 525
C PP V NA + G + ++ +Y CE + + G SV C G WS + C
Sbjct: 2 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCN 61
Query: 526 YVNCGTPT-IHKGSFVLINGTTTY---GSIAQFTCEPDYWLNGA--EELVCNRDGKWSYD 579
+C PT ++ S T Y G++ ++ C P Y + +L C ++ KWS
Sbjct: 62 R-SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTA 120
Query: 580 IPSCELTSCPEP-EVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDG---EWS 635
+ C+ SCP P E+ +G +TI F C G+KL G + C G +WS
Sbjct: 121 VEFCKKKSCPNPGEIRNGQIDVPGGILFGATITFSCNTGYKLFGSTSSFCLISGSSVQWS 180
Query: 636 GDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCT---EEF 692
P C I C P + G ++ + Y+C + ++G CT +E
Sbjct: 181 DPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEG 240
Query: 693 QWSDSSPRC 701
+WS P C
Sbjct: 241 EWSGPPPEC 249
Score = 91.5 bits (217), Expect = 2e-17
Identities = 78/271 (28%), Positives = 111/271 (40%), Gaps = 35/271 (12%)
Query: 645 DCGKLPTLPYGTMELLNGTTHL--GSVIQYSCTTNYRLVGPVRRT--CTEEFQWSDSSPR 700
DCG P +P L G T +VI Y C ++ + + + C + QWSD
Sbjct: 1 DCGLPPDVP-NAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEF 59
Query: 701 CEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVI 760
C C P N S I N + +G +V+Y C GY+
Sbjct: 60 CNR-SCEVPTRL---------NSASLKQPYITQ-------NYFPVGTVVEYECRPGYRR- 101
Query: 761 GESLS---TCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENW 817
SLS TC N +WS C+ C NPG I NG++ +P F GAT + C+ +
Sbjct: 102 EPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILF-GATITFSCNTGY 160
Query: 818 ELEGVIRRMCQENGT---WSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQ 874
+L G C +G+ WS P C+EI CP P QI G + Y
Sbjct: 161 KLFGSTSSFCLISGSSVQWSDPLPECREIYCPAP-PQIDNGI-IQGERDHYGYRQSVTYA 218
Query: 875 CERGYNLKGHQTRTCI---SKGQWNGTVPVC 902
C +G+ + G + C +G+W+G P C
Sbjct: 219 CNKGFTMIGEHSIYCTVNNDEGEWSGPPPEC 249
Score = 85.0 bits (201), Expect = 1e-15
Identities = 70/271 (25%), Positives = 111/271 (40%), Gaps = 38/271 (14%)
Query: 528 NCGTPTIHKGSFVLINGTTTY--GSIAQFTCEPDYWLNGAEE--LVCNRDGKWSYDIPSC 583
+CG P + + G T++ ++ + CE + E+ ++C + +WS DI
Sbjct: 1 DCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWS-DIEEF 59
Query: 584 ELTSCPEP-EVPSGGYMEAF---DYY-VHSTINFHCEAGHKLIGE--PNLVCQQDGEWSG 636
SC P + S + + +Y+ V + + + C G++ P L C Q+ +WS
Sbjct: 60 CNRSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWST 119
Query: 637 DSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCT---EEFQ 693
C+ C + G +++ G G+ I +SC T Y+L G C Q
Sbjct: 120 AVEFCKKKSCPNPGEIRNGQIDVPGGIL-FGATITFSCNTGYKLFGSTSSFCLISGSSVQ 178
Query: 694 WSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRC 753
WSD P C EI C P + I+ +R H Y V Y C
Sbjct: 179 WSDPLPECREIYCPAPPQIDNGIIQ---GERDH----------------YGYRQSVTYAC 219
Query: 754 EKGYKVIGESLSTC---EDNGQWSGTTPTCQ 781
KG+ +IGE C D G+WSG P C+
Sbjct: 220 NKGFTMIGEHSIYCTVNNDEGEWSGPPPECR 250
Score = 85.0 bits (201), Expect = 1e-15
Identities = 64/248 (25%), Positives = 101/248 (40%), Gaps = 20/248 (8%)
Query: 413 GLTPIEDGDVALIDNRTTHGARAL--YSCRENFTLVGNPERT--CGDEGIWDGEAPRCLF 468
GL P ++ RT+ + Y C E+F + + + C W C
Sbjct: 3 GLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNR 62
Query: 469 DWCPDPPAVSNAS-----VTVNGHKAGSLASYTCENGHILSGSTS--VTCTLGGAWSGVP 521
C P +++AS +T N G++ Y C G+ S S +TC WS
Sbjct: 63 S-CEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAV 121
Query: 522 PSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDG---KWSY 578
CK +C P + + + G +G+ F+C Y L G+ C G +WS
Sbjct: 122 EFCKKKSCPNPGEIRNGQIDVPGGILFGATITFSCNTGYKLFGSTSSFCLISGSSVQWSD 181
Query: 579 DIPSCELTSCP-EPEVPSGGYMEAFDYY-VHSTINFHCEAGHKLIGEPNLVC---QQDGE 633
+P C CP P++ +G D+Y ++ + C G +IGE ++ C +GE
Sbjct: 182 PLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGE 241
Query: 634 WSGDSPTC 641
WSG P C
Sbjct: 242 WSGPPPEC 249
Score = 82.2 bits (194), Expect = 9e-15
Identities = 66/242 (27%), Positives = 98/242 (40%), Gaps = 21/242 (8%)
Query: 317 GEQNCVVLDGGRGWLWNDVGCNLDYLHWICQYLPPTCGSPDKLLNTTILGNDYDVGSRIV 376
GE++ V+ G W + CN C+ PT + L I N + VG+ +
Sbjct: 40 GEKDSVICLKGSQWSDIEEFCNRS-----CEV--PTRLNSASLKQPYITQNYFPVGTVVE 92
Query: 377 YKCPEGHMLLGDKSRH--CKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRTTHGAR 434
Y+C G+ S C ++ WS A CK +C I +G + + GA
Sbjct: 93 YECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQID-VPGGILFGAT 151
Query: 435 ALYSCRENFTLVGNPERTC---GDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGS 491
+SC + L G+ C G W P C +CP PP + N + G
Sbjct: 152 ITFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGY 211
Query: 492 LAS--YTCENGHILSGSTSVTCTLG---GAWSGVPPSCKYVNCGT---PTIHKGSFVLIN 543
S Y C G + G S+ CT+ G WSG PP C+ + + PT+HK + V +
Sbjct: 212 RQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTVHKPTTVNVP 271
Query: 544 GT 545
T
Sbjct: 272 TT 273
Score = 74.5 bits (175), Expect = 2e-12
Identities = 66/267 (24%), Positives = 113/267 (42%), Gaps = 38/267 (14%)
Query: 591 PEVPSGG-YMEAFDYYVHST-INFHCEAGH-KLIGEPN-LVCQQDGEWSGDSPTCEYIDC 646
P+VP+ +E + T I + CE K+ GE + ++C + +WS C C
Sbjct: 6 PDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNR-SC 64
Query: 647 GKLPT-LPYGTME---LLNGTTHLGSVIQYSCTTNYRLVGPV--RRTCTEEFQWSDSSPR 700
++PT L +++ + +G+V++Y C YR + + TC + +WS +
Sbjct: 65 -EVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEF 123
Query: 701 CEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVI 760
C++ C +P + V G GA + + C GYK+
Sbjct: 124 CKKKSCPNPGEIRNGQIDVPGG--------------------ILFGATITFSCNTGYKLF 163
Query: 761 GESLSTCEDNG---QWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENW 817
G + S C +G QWS P C+ + C P +I+NG + + Y + Y C++ +
Sbjct: 164 GSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGF 223
Query: 818 ELEGVIRRMCQEN---GTWSLEPPICK 841
+ G C N G WS PP C+
Sbjct: 224 TMIGEHSIYCTVNNDEGEWSGPPPECR 250
Score = 72.9 bits (171), Expect = 6e-12
Identities = 53/191 (27%), Positives = 82/191 (42%), Gaps = 17/191 (8%)
Query: 784 DCGNPGRIENGKVTLPSNATFYGATAF-YQCDENW-----ELEGVIRRMCQENGTWSLEP 837
DCG P + N + L +F T Y+C+E++ E + VI C + WS
Sbjct: 1 DCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVI---CLKGSQWSDIE 57
Query: 838 PICKEITCPDPSAQIKAGSGLLVVTST-LSIGGEAHYQCERGYNLKGHQTR--TCISKGQ 894
C +C P+ A +T +G Y+C GY + + TC+ +
Sbjct: 58 EFCNR-SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLK 116
Query: 895 WNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDG- 953
W+ V C C +PG I NG+I + G LFG+++ + C + Y+ G CL G
Sbjct: 117 WSTAVEFCKKKSCPNPGEIRNGQIDVP-GGILFGATITFSCNTGYKLFGSTSSFCLISGS 175
Query: 954 --RWSGEEPSC 962
+WS P C
Sbjct: 176 SVQWSDPLPEC 186
Score = 35.1 bits (77), Expect = 1.4
Identities = 17/60 (28%), Positives = 28/60 (46%), Gaps = 5/60 (8%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRG---DWTLEPPFC 58
C +P N ++ +P I+ G + C+ GY+LFG+ C + G W+ P C
Sbjct: 129 CPNPGEIRNGQIDVPG--GILFGATITFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPEC 186
Score = 32.3 bits (70), Expect = 9.7
Identities = 16/59 (27%), Positives = 29/59 (49%), Gaps = 2/59 (3%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGY-ELFGARQRECTLRG-DWTLEPPFC 58
CG P PNA+ ++ + T+ Y+C+E + ++ G + L+G W+ FC
Sbjct: 2 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFC 60
Score = 32.3 bits (70), Expect = 9.7
Identities = 19/67 (28%), Positives = 32/67 (47%), Gaps = 6/67 (8%)
Query: 29 YECDEGYELFGARQRECTL---RGDWTLEPPFC-GTNVAFRKP--ANQSTTVRGGAAANG 82
Y C++G+ + G CT+ G+W+ PP C G ++ + P ++ TTV
Sbjct: 217 YACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTVHKPTTVNVPTTEVS 276
Query: 83 NDGEKTT 89
+KTT
Sbjct: 277 PTSQKTT 283
>S80305-1|AAB21330.1| 345|Homo sapiens beta 2-glycoprotein I
protein.
Length = 345
Score = 97.1 bits (231), Expect = 3e-19
Identities = 58/220 (26%), Positives = 88/220 (40%), Gaps = 11/220 (5%)
Query: 432 GARALYSCRENFTLVGNPER-TCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAG 490
G YSC+ + G + C G+W +C CP + N +V +
Sbjct: 44 GEEITYSCKPGYVSRGGMRKFICPLTGLWPINTLKCTPRVCPFAGILENGAVRYTTFEYP 103
Query: 491 SLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTIHKGSFVLI-----NGT 545
+ S++C G L+G+ S CT G WS P C + C P+I + + +
Sbjct: 104 NTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAPIICPPPSIPTFATLRVYKPSAGNN 163
Query: 546 TTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGG---YMEAF 602
+ Y A F C P + + G + + C G W+ +P C CP P P G Y
Sbjct: 164 SLYRDTAVFECLPQHAMFGNDTITCTTHGNWT-KLPECREVKCPFPSRPDNGFVNYPAKP 222
Query: 603 DYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCE 642
Y F C G+ L G + C + G WS P+C+
Sbjct: 223 TLYYKDKATFGCHDGYSLDGPEEIECTKLGNWSA-MPSCK 261
Score = 92.7 bits (220), Expect = 6e-18
Identities = 64/251 (25%), Positives = 100/251 (39%), Gaps = 16/251 (6%)
Query: 471 CPDPPAVSNASVTV--NGHKAGSLASYTCENGHILSGST-SVTCTLGGAWSGVPPSCKYV 527
CP P + ++V ++ G +Y+C+ G++ G C L G W C
Sbjct: 23 CPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYVSRGGMRKFICPLTGLWPINTLKCTPR 82
Query: 528 NCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTS 587
C I + V T Y + F+C ++LNGA+ C +GKWS ++P C
Sbjct: 83 VCPFAGILENGAVRYT-TFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAPII 141
Query: 588 CPEPEVPSGGYMEAF------DYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTC 641
CP P +P+ + + + T F C H + G + C G W+ P C
Sbjct: 142 CPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWT-KLPEC 200
Query: 642 EYIDCGKLPTLP-YGTMEL-LNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSP 699
+ C P+ P G + T + + C Y L GP CT+ WS + P
Sbjct: 201 REVKC-PFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSLDGPEEIECTKLGNWS-AMP 258
Query: 700 RCEEIRCSDPI 710
C + C P+
Sbjct: 259 SC-KASCKVPV 268
Score = 90.2 bits (214), Expect = 3e-17
Identities = 68/237 (28%), Positives = 93/237 (39%), Gaps = 10/237 (4%)
Query: 743 YRIGALVKYRCEKGYKVIGESLS-TCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSN 801
Y G + Y C+ GY G C G W T C C G +ENG V
Sbjct: 41 YEPGEEITYSCKPGYVSRGGMRKFICPLTGLWPINTLKCTPRVCPFAGILENGAVRY--- 97
Query: 802 ATF-YGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLV 860
TF Y T + C+ + L G C E G WS E P+C I CP PS A +
Sbjct: 98 TTFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAPIICPPPSIPTFATLRVYK 157
Query: 861 VT--STLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKI 918
+ + A ++C + + G+ T TC + G W +P C + C P +NG +
Sbjct: 158 PSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWT-KLPECREVKCPFPSRPDNGFV 216
Query: 919 VISNGSTL-FGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCELATNEAVDSGT 974
TL + + C Y GP +C G WS PSC+ + V T
Sbjct: 217 NYPAKPTLYYKDKATFGCHDGYSLDGPEEIECTKLGNWSA-MPSCKASCKVPVKKAT 272
Score = 84.2 bits (199), Expect = 2e-15
Identities = 71/266 (26%), Positives = 109/266 (40%), Gaps = 24/266 (9%)
Query: 587 SCPEPE-VPSGGYMEAFDYYVHST-INFHCEAGH-KLIGEPNLVCQQDGEWSGDSPTCEY 643
+CP+P+ +P + +Y I + C+ G+ G +C G W ++ C
Sbjct: 22 TCPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYVSRGGMRKFICPLTGLWPINTLKCTP 81
Query: 644 IDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEE 703
C L G + T + I +SC T + L G CTEE +WS P C
Sbjct: 82 RVCPFAGILENGAVRYT--TFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAP 139
Query: 704 IRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGES 763
I C P + + + V S G+ + YR A+ + C + + G
Sbjct: 140 IICPPPSIPTFATLRV--YKPSAGN-----------NSLYRDTAV--FECLPQHAMFGND 184
Query: 764 LSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNAT-FYGATAFYQCDENWELEGV 822
TC +G W+ P C+ V C P R +NG V P+ T +Y A + C + + L+G
Sbjct: 185 TITCTTHGNWT-KLPECREVKCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSLDGP 243
Query: 823 IRRMCQENGTWSLEPPICKEITCPDP 848
C + G WS P CK +C P
Sbjct: 244 EEIECTKLGNWSAMPS-CK-ASCKVP 267
Score = 77.4 bits (182), Expect = 3e-13
Identities = 68/270 (25%), Positives = 103/270 (38%), Gaps = 30/270 (11%)
Query: 646 CGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRR-TCTEEFQWSDSSPRCEEI 704
C K LP+ T+ L G I YSC Y G +R+ C W ++ +C
Sbjct: 23 CPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYVSRGGMRKFICPLTGLWPINTLKCTPR 82
Query: 705 RCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESL 764
C + E V T T+ + + C G+ + G
Sbjct: 83 VCPFAGILENGAVRYT---------------------TFEYPNTISFSCNTGFYLNGADS 121
Query: 765 STCEDNGQWSGTTPTCQYVDCGNPG--RIENGKVTLPS--NATFYGATAFYQCDENWELE 820
+ C + G+WS P C + C P +V PS N + Y TA ++C +
Sbjct: 122 AKCTEEGKWSPELPVCAPIICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMF 181
Query: 821 GVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYN 880
G C +G W+ + P C+E+ CP PS + G TL +A + C GY+
Sbjct: 182 GNDTITCTTHGNWT-KLPECREVKCPFPS-RPDNGFVNYPAKPTLYYKDKATFGCHDGYS 239
Query: 881 LKGHQTRTCISKGQWNGTVPVCIPIDCRSP 910
L G + C G W+ +P C C+ P
Sbjct: 240 LDGPEEIECTKLGNWS-AMPSC-KASCKVP 267
Score = 67.3 bits (157), Expect = 3e-10
Identities = 49/190 (25%), Positives = 73/190 (38%), Gaps = 10/190 (5%)
Query: 350 PPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYV 409
P C L N + ++ + I + C G L G S C ++G WS P C +
Sbjct: 81 PRVCPFAGILENGAVRYTTFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAPI 140
Query: 410 NCGGLTPIEDGDVAL----IDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPR 465
C + + + N + + A++ C + GN TC G W + P
Sbjct: 141 ICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWT-KLPE 199
Query: 466 CLFDWCPDPPAVSNASVTVNGHKA---GSLASYTCENGHILSGSTSVTCTLGGAWSGVPP 522
C CP P N V A++ C +G+ L G + CT G WS + P
Sbjct: 200 CREVKCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSLDGPEEIECTKLGNWSAM-P 258
Query: 523 SCKYVNCGTP 532
SCK +C P
Sbjct: 259 SCK-ASCKVP 267
Score = 43.6 bits (98), Expect = 0.004
Identities = 22/77 (28%), Positives = 36/77 (46%), Gaps = 3/77 (3%)
Query: 1 RCGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGT 60
+C P+ P N V+ P + + A + C +GY L G + ECT G+W+ P
Sbjct: 204 KCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSLDGPEEIECTKLGNWSAMP---SC 260
Query: 61 NVAFRKPANQSTTVRGG 77
+ + P ++T V G
Sbjct: 261 KASCKVPVKKATVVYQG 277
Score = 32.7 bits (71), Expect = 7.4
Identities = 20/57 (35%), Positives = 28/57 (49%), Gaps = 3/57 (5%)
Query: 2 CGHPAVPPNA--RVSIPNE-ENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEP 55
C P++P A RV P+ N + AV+EC + +FG CT G+WT P
Sbjct: 142 CPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWTKLP 198
Score = 32.3 bits (70), Expect = 9.7
Identities = 12/30 (40%), Positives = 17/30 (56%)
Query: 29 YECDEGYELFGARQRECTLRGDWTLEPPFC 58
+ C+ G+ L GA +CT G W+ E P C
Sbjct: 108 FSCNTGFYLNGADSAKCTEEGKWSPELPVC 137
>M62839-1|AAA51766.1| 345|Homo sapiens apolipoprotein H protein.
Length = 345
Score = 97.1 bits (231), Expect = 3e-19
Identities = 58/220 (26%), Positives = 88/220 (40%), Gaps = 11/220 (5%)
Query: 432 GARALYSCRENFTLVGNPER-TCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAG 490
G YSC+ + G + C G+W +C CP + N +V +
Sbjct: 44 GEEITYSCKPGYVSRGGMRKFICPLTGLWPINTLKCTPRVCPFAGILENGAVRYTTFEYP 103
Query: 491 SLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTIHKGSFVLI-----NGT 545
+ S++C G L+G+ S CT G WS P C + C P+I + + +
Sbjct: 104 NTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAPIICPPPSIPTFATLRVYKPSAGNN 163
Query: 546 TTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGG---YMEAF 602
+ Y A F C P + + G + + C G W+ +P C CP P P G Y
Sbjct: 164 SLYRDTAVFECLPQHAMFGNDTITCTTHGNWT-KLPECREVKCPFPSRPDNGFVNYPAKP 222
Query: 603 DYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCE 642
Y F C G+ L G + C + G WS P+C+
Sbjct: 223 TLYYKDKATFGCHDGYSLDGPEEIECTKLGNWSA-MPSCK 261
Score = 92.7 bits (220), Expect = 6e-18
Identities = 64/251 (25%), Positives = 100/251 (39%), Gaps = 16/251 (6%)
Query: 471 CPDPPAVSNASVTV--NGHKAGSLASYTCENGHILSGST-SVTCTLGGAWSGVPPSCKYV 527
CP P + ++V ++ G +Y+C+ G++ G C L G W C
Sbjct: 23 CPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYVSRGGMRKFICPLTGLWPINTLKCTPR 82
Query: 528 NCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTS 587
C I + V T Y + F+C ++LNGA+ C +GKWS ++P C
Sbjct: 83 VCPFAGILENGAVRYT-TFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAPII 141
Query: 588 CPEPEVPSGGYMEAF------DYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTC 641
CP P +P+ + + + T F C H + G + C G W+ P C
Sbjct: 142 CPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWT-KLPEC 200
Query: 642 EYIDCGKLPTLP-YGTMEL-LNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSP 699
+ C P+ P G + T + + C Y L GP CT+ WS + P
Sbjct: 201 REVKC-PFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSLDGPEEIECTKLGNWS-AMP 258
Query: 700 RCEEIRCSDPI 710
C + C P+
Sbjct: 259 SC-KASCKVPV 268
Score = 90.2 bits (214), Expect = 3e-17
Identities = 68/237 (28%), Positives = 93/237 (39%), Gaps = 10/237 (4%)
Query: 743 YRIGALVKYRCEKGYKVIGESLS-TCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSN 801
Y G + Y C+ GY G C G W T C C G +ENG V
Sbjct: 41 YEPGEEITYSCKPGYVSRGGMRKFICPLTGLWPINTLKCTPRVCPFAGILENGAVRY--- 97
Query: 802 ATF-YGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLV 860
TF Y T + C+ + L G C E G WS E P+C I CP PS A +
Sbjct: 98 TTFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAPIICPPPSIPTFATLRVYK 157
Query: 861 VT--STLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKI 918
+ + A ++C + + G+ T TC + G W +P C + C P +NG +
Sbjct: 158 PSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWT-KLPECREVKCPFPSRPDNGFV 216
Query: 919 VISNGSTL-FGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCELATNEAVDSGT 974
TL + + C Y GP +C G WS PSC+ + V T
Sbjct: 217 NYPAKPTLYYKDKATFGCHDGYSLDGPEEIECTKLGNWSA-MPSCKASCKVPVKKAT 272
Score = 84.2 bits (199), Expect = 2e-15
Identities = 71/266 (26%), Positives = 109/266 (40%), Gaps = 24/266 (9%)
Query: 587 SCPEPE-VPSGGYMEAFDYYVHST-INFHCEAGH-KLIGEPNLVCQQDGEWSGDSPTCEY 643
+CP+P+ +P + +Y I + C+ G+ G +C G W ++ C
Sbjct: 22 TCPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYVSRGGMRKFICPLTGLWPINTLKCTP 81
Query: 644 IDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEE 703
C L G + T + I +SC T + L G CTEE +WS P C
Sbjct: 82 RVCPFAGILENGAVRYT--TFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAP 139
Query: 704 IRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGES 763
I C P + + + V S G+ + YR A+ + C + + G
Sbjct: 140 IICPPPSIPTFATLRV--YKPSAGN-----------NSLYRDTAV--FECLPQHAMFGND 184
Query: 764 LSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNAT-FYGATAFYQCDENWELEGV 822
TC +G W+ P C+ V C P R +NG V P+ T +Y A + C + + L+G
Sbjct: 185 TITCTTHGNWT-KLPECREVKCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSLDGP 243
Query: 823 IRRMCQENGTWSLEPPICKEITCPDP 848
C + G WS P CK +C P
Sbjct: 244 EEIECTKLGNWSAMPS-CK-ASCKVP 267
Score = 77.4 bits (182), Expect = 3e-13
Identities = 68/270 (25%), Positives = 103/270 (38%), Gaps = 30/270 (11%)
Query: 646 CGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRR-TCTEEFQWSDSSPRCEEI 704
C K LP+ T+ L G I YSC Y G +R+ C W ++ +C
Sbjct: 23 CPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYVSRGGMRKFICPLTGLWPINTLKCTPR 82
Query: 705 RCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESL 764
C + E V T T+ + + C G+ + G
Sbjct: 83 VCPFAGILENGAVRYT---------------------TFEYPNTISFSCNTGFYLNGADS 121
Query: 765 STCEDNGQWSGTTPTCQYVDCGNPG--RIENGKVTLPS--NATFYGATAFYQCDENWELE 820
+ C + G+WS P C + C P +V PS N + Y TA ++C +
Sbjct: 122 AKCTEEGKWSPELPVCAPIICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMF 181
Query: 821 GVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYN 880
G C +G W+ + P C+E+ CP PS + G TL +A + C GY+
Sbjct: 182 GNDTITCTTHGNWT-KLPECREVKCPFPS-RPDNGFVNYPAKPTLYYKDKATFGCHDGYS 239
Query: 881 LKGHQTRTCISKGQWNGTVPVCIPIDCRSP 910
L G + C G W+ +P C C+ P
Sbjct: 240 LDGPEEIECTKLGNWS-AMPSC-KASCKVP 267
Score = 67.3 bits (157), Expect = 3e-10
Identities = 49/190 (25%), Positives = 73/190 (38%), Gaps = 10/190 (5%)
Query: 350 PPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYV 409
P C L N + ++ + I + C G L G S C ++G WS P C +
Sbjct: 81 PRVCPFAGILENGAVRYTTFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAPI 140
Query: 410 NCGGLTPIEDGDVAL----IDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPR 465
C + + + N + + A++ C + GN TC G W + P
Sbjct: 141 ICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWT-KLPE 199
Query: 466 CLFDWCPDPPAVSNASVTVNGHKA---GSLASYTCENGHILSGSTSVTCTLGGAWSGVPP 522
C CP P N V A++ C +G+ L G + CT G WS + P
Sbjct: 200 CREVKCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSLDGPEEIECTKLGNWSAM-P 258
Query: 523 SCKYVNCGTP 532
SCK +C P
Sbjct: 259 SCK-ASCKVP 267
Score = 43.6 bits (98), Expect = 0.004
Identities = 22/77 (28%), Positives = 36/77 (46%), Gaps = 3/77 (3%)
Query: 1 RCGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGT 60
+C P+ P N V+ P + + A + C +GY L G + ECT G+W+ P
Sbjct: 204 KCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSLDGPEEIECTKLGNWSAMP---SC 260
Query: 61 NVAFRKPANQSTTVRGG 77
+ + P ++T V G
Sbjct: 261 KASCKVPVKKATVVYQG 277
Score = 32.7 bits (71), Expect = 7.4
Identities = 20/57 (35%), Positives = 28/57 (49%), Gaps = 3/57 (5%)
Query: 2 CGHPAVPPNA--RVSIPNE-ENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEP 55
C P++P A RV P+ N + AV+EC + +FG CT G+WT P
Sbjct: 142 CPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWTKLP 198
Score = 32.3 bits (70), Expect = 9.7
Identities = 12/30 (40%), Positives = 17/30 (56%)
Query: 29 YECDEGYELFGARQRECTLRGDWTLEPPFC 58
+ C+ G+ L GA +CT G W+ E P C
Sbjct: 108 FSCNTGFYLNGADSAKCTEEGKWSPELPVC 137
>BC026283-1|AAH26283.1| 345|Homo sapiens apolipoprotein H
(beta-2-glycoprotein I) protein.
Length = 345
Score = 97.1 bits (231), Expect = 3e-19
Identities = 58/220 (26%), Positives = 88/220 (40%), Gaps = 11/220 (5%)
Query: 432 GARALYSCRENFTLVGNPER-TCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAG 490
G YSC+ + G + C G+W +C CP + N +V +
Sbjct: 44 GEEITYSCKPGYVSRGGMRKFICPLTGLWPINTLKCTPRVCPFAGILENGAVRYTTFEYP 103
Query: 491 SLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTIHKGSFVLI-----NGT 545
+ S++C G L+G+ S CT G WS P C + C P+I + + +
Sbjct: 104 NTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAPIICPPPSIPTFATLRVYKPSAGNN 163
Query: 546 TTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGG---YMEAF 602
+ Y A F C P + + G + + C G W+ +P C CP P P G Y
Sbjct: 164 SLYRDTAVFECLPQHAMFGNDTITCTTHGNWT-KLPECREVKCPFPSRPDNGFVNYPAKP 222
Query: 603 DYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCE 642
Y F C G+ L G + C + G WS P+C+
Sbjct: 223 TLYYKDKATFGCHDGYSLDGPEEIECTKLGNWSA-MPSCK 261
Score = 92.7 bits (220), Expect = 6e-18
Identities = 64/251 (25%), Positives = 100/251 (39%), Gaps = 16/251 (6%)
Query: 471 CPDPPAVSNASVTV--NGHKAGSLASYTCENGHILSGST-SVTCTLGGAWSGVPPSCKYV 527
CP P + ++V ++ G +Y+C+ G++ G C L G W C
Sbjct: 23 CPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYVSRGGMRKFICPLTGLWPINTLKCTPR 82
Query: 528 NCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTS 587
C I + V T Y + F+C ++LNGA+ C +GKWS ++P C
Sbjct: 83 VCPFAGILENGAVRYT-TFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAPII 141
Query: 588 CPEPEVPSGGYMEAF------DYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTC 641
CP P +P+ + + + T F C H + G + C G W+ P C
Sbjct: 142 CPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWT-KLPEC 200
Query: 642 EYIDCGKLPTLP-YGTMEL-LNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSP 699
+ C P+ P G + T + + C Y L GP CT+ WS + P
Sbjct: 201 REVKC-PFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSLDGPEEIECTKLGNWS-AMP 258
Query: 700 RCEEIRCSDPI 710
C + C P+
Sbjct: 259 SC-KASCKVPV 268
Score = 90.2 bits (214), Expect = 3e-17
Identities = 68/237 (28%), Positives = 93/237 (39%), Gaps = 10/237 (4%)
Query: 743 YRIGALVKYRCEKGYKVIGESLS-TCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSN 801
Y G + Y C+ GY G C G W T C C G +ENG V
Sbjct: 41 YEPGEEITYSCKPGYVSRGGMRKFICPLTGLWPINTLKCTPRVCPFAGILENGAVRY--- 97
Query: 802 ATF-YGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLV 860
TF Y T + C+ + L G C E G WS E P+C I CP PS A +
Sbjct: 98 TTFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAPIICPPPSIPTFATLRVYK 157
Query: 861 VT--STLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKI 918
+ + A ++C + + G+ T TC + G W +P C + C P +NG +
Sbjct: 158 PSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWT-KLPECREVKCPFPSRPDNGFV 216
Query: 919 VISNGSTL-FGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCELATNEAVDSGT 974
TL + + C Y GP +C G WS PSC+ + V T
Sbjct: 217 NYPAKPTLYYKDKATFGCHDGYSLDGPEEIECTKLGNWSA-MPSCKASCKVPVKKAT 272
Score = 84.2 bits (199), Expect = 2e-15
Identities = 71/266 (26%), Positives = 109/266 (40%), Gaps = 24/266 (9%)
Query: 587 SCPEPE-VPSGGYMEAFDYYVHST-INFHCEAGH-KLIGEPNLVCQQDGEWSGDSPTCEY 643
+CP+P+ +P + +Y I + C+ G+ G +C G W ++ C
Sbjct: 22 TCPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYVSRGGMRKFICPLTGLWPINTLKCTP 81
Query: 644 IDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEE 703
C L G + T + I +SC T + L G CTEE +WS P C
Sbjct: 82 RVCPFAGILENGAVRYT--TFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAP 139
Query: 704 IRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGES 763
I C P + + + V S G+ + YR A+ + C + + G
Sbjct: 140 IICPPPSIPTFATLRV--YKPSAGN-----------NSLYRDTAV--FECLPQHAMFGND 184
Query: 764 LSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNAT-FYGATAFYQCDENWELEGV 822
TC +G W+ P C+ V C P R +NG V P+ T +Y A + C + + L+G
Sbjct: 185 TITCTTHGNWT-KLPECREVKCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSLDGP 243
Query: 823 IRRMCQENGTWSLEPPICKEITCPDP 848
C + G WS P CK +C P
Sbjct: 244 EEIECTKLGNWSAMPS-CK-ASCKVP 267
Score = 77.4 bits (182), Expect = 3e-13
Identities = 68/270 (25%), Positives = 103/270 (38%), Gaps = 30/270 (11%)
Query: 646 CGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRR-TCTEEFQWSDSSPRCEEI 704
C K LP+ T+ L G I YSC Y G +R+ C W ++ +C
Sbjct: 23 CPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYVSRGGMRKFICPLTGLWPINTLKCTPR 82
Query: 705 RCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESL 764
C + E V T T+ + + C G+ + G
Sbjct: 83 VCPFAGILENGAVRYT---------------------TFEYPNTISFSCNTGFYLNGADS 121
Query: 765 STCEDNGQWSGTTPTCQYVDCGNPG--RIENGKVTLPS--NATFYGATAFYQCDENWELE 820
+ C + G+WS P C + C P +V PS N + Y TA ++C +
Sbjct: 122 AKCTEEGKWSPELPVCAPIICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMF 181
Query: 821 GVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYN 880
G C +G W+ + P C+E+ CP PS + G TL +A + C GY+
Sbjct: 182 GNDTITCTTHGNWT-KLPECREVKCPFPS-RPDNGFVNYPAKPTLYYKDKATFGCHDGYS 239
Query: 881 LKGHQTRTCISKGQWNGTVPVCIPIDCRSP 910
L G + C G W+ +P C C+ P
Sbjct: 240 LDGPEEIECTKLGNWS-AMPSC-KASCKVP 267
Score = 67.3 bits (157), Expect = 3e-10
Identities = 49/190 (25%), Positives = 73/190 (38%), Gaps = 10/190 (5%)
Query: 350 PPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYV 409
P C L N + ++ + I + C G L G S C ++G WS P C +
Sbjct: 81 PRVCPFAGILENGAVRYTTFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAPI 140
Query: 410 NCGGLTPIEDGDVAL----IDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPR 465
C + + + N + + A++ C + GN TC G W + P
Sbjct: 141 ICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWT-KLPE 199
Query: 466 CLFDWCPDPPAVSNASVTVNGHKA---GSLASYTCENGHILSGSTSVTCTLGGAWSGVPP 522
C CP P N V A++ C +G+ L G + CT G WS + P
Sbjct: 200 CREVKCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSLDGPEEIECTKLGNWSAM-P 258
Query: 523 SCKYVNCGTP 532
SCK +C P
Sbjct: 259 SCK-ASCKVP 267
Score = 43.6 bits (98), Expect = 0.004
Identities = 22/77 (28%), Positives = 36/77 (46%), Gaps = 3/77 (3%)
Query: 1 RCGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGT 60
+C P+ P N V+ P + + A + C +GY L G + ECT G+W+ P
Sbjct: 204 KCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSLDGPEEIECTKLGNWSAMP---SC 260
Query: 61 NVAFRKPANQSTTVRGG 77
+ + P ++T V G
Sbjct: 261 KASCKVPVKKATVVYQG 277
Score = 32.7 bits (71), Expect = 7.4
Identities = 20/57 (35%), Positives = 28/57 (49%), Gaps = 3/57 (5%)
Query: 2 CGHPAVPPNA--RVSIPNE-ENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEP 55
C P++P A RV P+ N + AV+EC + +FG CT G+WT P
Sbjct: 142 CPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWTKLP 198
Score = 32.3 bits (70), Expect = 9.7
Identities = 12/30 (40%), Positives = 17/30 (56%)
Query: 29 YECDEGYELFGARQRECTLRGDWTLEPPFC 58
+ C+ G+ L GA +CT G W+ E P C
Sbjct: 108 FSCNTGFYLNGADSAKCTEEGKWSPELPVC 137
>BC020703-1|AAH20703.1| 345|Homo sapiens apolipoprotein H
(beta-2-glycoprotein I) protein.
Length = 345
Score = 97.1 bits (231), Expect = 3e-19
Identities = 58/220 (26%), Positives = 88/220 (40%), Gaps = 11/220 (5%)
Query: 432 GARALYSCRENFTLVGNPER-TCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAG 490
G YSC+ + G + C G+W +C CP + N +V +
Sbjct: 44 GEEITYSCKPGYVSRGGMRKFICPLTGLWPINTLKCTPRVCPFAGILENGAVRYTTFEYP 103
Query: 491 SLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTIHKGSFVLI-----NGT 545
+ S++C G L+G+ S CT G WS P C + C P+I + + +
Sbjct: 104 NTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAPIICPPPSIPTFATLRVYKPSAGNN 163
Query: 546 TTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGG---YMEAF 602
+ Y A F C P + + G + + C G W+ +P C CP P P G Y
Sbjct: 164 SLYRDTAVFECLPQHAMFGNDTITCTTHGNWT-KLPECREVKCPFPSRPDNGFVNYPAKP 222
Query: 603 DYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCE 642
Y F C G+ L G + C + G WS P+C+
Sbjct: 223 TLYYKDKATFGCHDGYSLDGPEEIECTKLGNWSA-MPSCK 261
Score = 92.7 bits (220), Expect = 6e-18
Identities = 64/251 (25%), Positives = 100/251 (39%), Gaps = 16/251 (6%)
Query: 471 CPDPPAVSNASVTV--NGHKAGSLASYTCENGHILSGST-SVTCTLGGAWSGVPPSCKYV 527
CP P + ++V ++ G +Y+C+ G++ G C L G W C
Sbjct: 23 CPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYVSRGGMRKFICPLTGLWPINTLKCTPR 82
Query: 528 NCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTS 587
C I + V T Y + F+C ++LNGA+ C +GKWS ++P C
Sbjct: 83 VCPFAGILENGAVRYT-TFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAPII 141
Query: 588 CPEPEVPSGGYMEAF------DYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTC 641
CP P +P+ + + + T F C H + G + C G W+ P C
Sbjct: 142 CPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWT-KLPEC 200
Query: 642 EYIDCGKLPTLP-YGTMEL-LNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSP 699
+ C P+ P G + T + + C Y L GP CT+ WS + P
Sbjct: 201 REVKC-PFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSLDGPEEIECTKLGNWS-AMP 258
Query: 700 RCEEIRCSDPI 710
C + C P+
Sbjct: 259 SC-KASCKVPV 268
Score = 90.2 bits (214), Expect = 3e-17
Identities = 68/237 (28%), Positives = 93/237 (39%), Gaps = 10/237 (4%)
Query: 743 YRIGALVKYRCEKGYKVIGESLS-TCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSN 801
Y G + Y C+ GY G C G W T C C G +ENG V
Sbjct: 41 YEPGEEITYSCKPGYVSRGGMRKFICPLTGLWPINTLKCTPRVCPFAGILENGAVRY--- 97
Query: 802 ATF-YGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLV 860
TF Y T + C+ + L G C E G WS E P+C I CP PS A +
Sbjct: 98 TTFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAPIICPPPSIPTFATLRVYK 157
Query: 861 VT--STLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKI 918
+ + A ++C + + G+ T TC + G W +P C + C P +NG +
Sbjct: 158 PSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWT-KLPECREVKCPFPSRPDNGFV 216
Query: 919 VISNGSTL-FGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCELATNEAVDSGT 974
TL + + C Y GP +C G WS PSC+ + V T
Sbjct: 217 NYPAKPTLYYKDKATFGCHDGYSLDGPEEIECTKLGNWSA-MPSCKASCKVPVKKAT 272
Score = 84.2 bits (199), Expect = 2e-15
Identities = 71/266 (26%), Positives = 109/266 (40%), Gaps = 24/266 (9%)
Query: 587 SCPEPE-VPSGGYMEAFDYYVHST-INFHCEAGH-KLIGEPNLVCQQDGEWSGDSPTCEY 643
+CP+P+ +P + +Y I + C+ G+ G +C G W ++ C
Sbjct: 22 TCPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYVSRGGMRKFICPLTGLWPINTLKCTP 81
Query: 644 IDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEE 703
C L G + T + I +SC T + L G CTEE +WS P C
Sbjct: 82 RVCPFAGILENGAVRYT--TFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAP 139
Query: 704 IRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGES 763
I C P + + + V S G+ + YR A+ + C + + G
Sbjct: 140 IICPPPSIPTFATLRV--YKPSAGN-----------NSLYRDTAV--FECLPQHAMFGND 184
Query: 764 LSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNAT-FYGATAFYQCDENWELEGV 822
TC +G W+ P C+ V C P R +NG V P+ T +Y A + C + + L+G
Sbjct: 185 TITCTTHGNWT-KLPECREVKCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSLDGP 243
Query: 823 IRRMCQENGTWSLEPPICKEITCPDP 848
C + G WS P CK +C P
Sbjct: 244 EEIECTKLGNWSAMPS-CK-ASCKVP 267
Score = 77.4 bits (182), Expect = 3e-13
Identities = 68/270 (25%), Positives = 103/270 (38%), Gaps = 30/270 (11%)
Query: 646 CGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRR-TCTEEFQWSDSSPRCEEI 704
C K LP+ T+ L G I YSC Y G +R+ C W ++ +C
Sbjct: 23 CPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYVSRGGMRKFICPLTGLWPINTLKCTPR 82
Query: 705 RCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESL 764
C + E V T T+ + + C G+ + G
Sbjct: 83 VCPFAGILENGAVRYT---------------------TFEYPNTISFSCNTGFYLNGADS 121
Query: 765 STCEDNGQWSGTTPTCQYVDCGNPG--RIENGKVTLPS--NATFYGATAFYQCDENWELE 820
+ C + G+WS P C + C P +V PS N + Y TA ++C +
Sbjct: 122 AKCTEEGKWSPELPVCAPIICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMF 181
Query: 821 GVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYN 880
G C +G W+ + P C+E+ CP PS + G TL +A + C GY+
Sbjct: 182 GNDTITCTTHGNWT-KLPECREVKCPFPS-RPDNGFVNYPAKPTLYYKDKATFGCHDGYS 239
Query: 881 LKGHQTRTCISKGQWNGTVPVCIPIDCRSP 910
L G + C G W+ +P C C+ P
Sbjct: 240 LDGPEEIECTKLGNWS-AMPSC-KASCKVP 267
Score = 67.3 bits (157), Expect = 3e-10
Identities = 49/190 (25%), Positives = 73/190 (38%), Gaps = 10/190 (5%)
Query: 350 PPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYV 409
P C L N + ++ + I + C G L G S C ++G WS P C +
Sbjct: 81 PRVCPFAGILENGAVRYTTFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAPI 140
Query: 410 NCGGLTPIEDGDVAL----IDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPR 465
C + + + N + + A++ C + GN TC G W + P
Sbjct: 141 ICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWT-KLPE 199
Query: 466 CLFDWCPDPPAVSNASVTVNGHKA---GSLASYTCENGHILSGSTSVTCTLGGAWSGVPP 522
C CP P N V A++ C +G+ L G + CT G WS + P
Sbjct: 200 CREVKCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSLDGPEEIECTKLGNWSAM-P 258
Query: 523 SCKYVNCGTP 532
SCK +C P
Sbjct: 259 SCK-ASCKVP 267
Score = 43.6 bits (98), Expect = 0.004
Identities = 22/77 (28%), Positives = 36/77 (46%), Gaps = 3/77 (3%)
Query: 1 RCGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGT 60
+C P+ P N V+ P + + A + C +GY L G + ECT G+W+ P
Sbjct: 204 KCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSLDGPEEIECTKLGNWSAMP---SC 260
Query: 61 NVAFRKPANQSTTVRGG 77
+ + P ++T V G
Sbjct: 261 KASCKVPVKKATVVYQG 277
Score = 32.7 bits (71), Expect = 7.4
Identities = 20/57 (35%), Positives = 28/57 (49%), Gaps = 3/57 (5%)
Query: 2 CGHPAVPPNA--RVSIPNE-ENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEP 55
C P++P A RV P+ N + AV+EC + +FG CT G+WT P
Sbjct: 142 CPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWTKLP 198
Score = 32.3 bits (70), Expect = 9.7
Identities = 12/30 (40%), Positives = 17/30 (56%)
Query: 29 YECDEGYELFGARQRECTLRGDWTLEPPFC 58
+ C+ G+ L GA +CT G W+ E P C
Sbjct: 108 FSCNTGFYLNGADSAKCTEEGKWSPELPVC 137
>AY322156-1|AAP72014.1| 345|Homo sapiens apolipoprotein H
(beta-2-glycoprotein I) protein.
Length = 345
Score = 97.1 bits (231), Expect = 3e-19
Identities = 58/220 (26%), Positives = 88/220 (40%), Gaps = 11/220 (5%)
Query: 432 GARALYSCRENFTLVGNPER-TCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAG 490
G YSC+ + G + C G+W +C CP + N +V +
Sbjct: 44 GEEITYSCKPGYVSRGGMRKFICPLTGLWPINTLKCTPRVCPFAGILENGAVRYTTFEYP 103
Query: 491 SLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTIHKGSFVLI-----NGT 545
+ S++C G L+G+ S CT G WS P C + C P+I + + +
Sbjct: 104 NTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAPIICPPPSIPTFATLRVYKPSAGNN 163
Query: 546 TTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGG---YMEAF 602
+ Y A F C P + + G + + C G W+ +P C CP P P G Y
Sbjct: 164 SLYRDTAVFECLPQHAMFGNDTITCTTHGNWT-KLPECREVKCPFPSRPDNGFVNYPAKP 222
Query: 603 DYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCE 642
Y F C G+ L G + C + G WS P+C+
Sbjct: 223 TLYYKDKATFGCHDGYSLDGPEEIECTKLGNWSA-MPSCK 261
Score = 92.7 bits (220), Expect = 6e-18
Identities = 64/251 (25%), Positives = 100/251 (39%), Gaps = 16/251 (6%)
Query: 471 CPDPPAVSNASVTV--NGHKAGSLASYTCENGHILSGST-SVTCTLGGAWSGVPPSCKYV 527
CP P + ++V ++ G +Y+C+ G++ G C L G W C
Sbjct: 23 CPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYVSRGGMRKFICPLTGLWPINTLKCTPR 82
Query: 528 NCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTS 587
C I + V T Y + F+C ++LNGA+ C +GKWS ++P C
Sbjct: 83 VCPFAGILENGAVRYT-TFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAPII 141
Query: 588 CPEPEVPSGGYMEAF------DYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTC 641
CP P +P+ + + + T F C H + G + C G W+ P C
Sbjct: 142 CPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWT-KLPEC 200
Query: 642 EYIDCGKLPTLP-YGTMEL-LNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSP 699
+ C P+ P G + T + + C Y L GP CT+ WS + P
Sbjct: 201 REVKC-PFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSLDGPEEIECTKLGNWS-AMP 258
Query: 700 RCEEIRCSDPI 710
C + C P+
Sbjct: 259 SC-KASCKVPV 268
Score = 90.2 bits (214), Expect = 3e-17
Identities = 68/237 (28%), Positives = 93/237 (39%), Gaps = 10/237 (4%)
Query: 743 YRIGALVKYRCEKGYKVIGESLS-TCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSN 801
Y G + Y C+ GY G C G W T C C G +ENG V
Sbjct: 41 YEPGEEITYSCKPGYVSRGGMRKFICPLTGLWPINTLKCTPRVCPFAGILENGAVRY--- 97
Query: 802 ATF-YGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLV 860
TF Y T + C+ + L G C E G WS E P+C I CP PS A +
Sbjct: 98 TTFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAPIICPPPSIPTFATLRVYK 157
Query: 861 VT--STLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKI 918
+ + A ++C + + G+ T TC + G W +P C + C P +NG +
Sbjct: 158 PSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWT-KLPECREVKCPFPSRPDNGFV 216
Query: 919 VISNGSTL-FGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCELATNEAVDSGT 974
TL + + C Y GP +C G WS PSC+ + V T
Sbjct: 217 NYPAKPTLYYKDKATFGCHDGYSLDGPEEIECTKLGNWSA-MPSCKASCKVPVKKAT 272
Score = 84.2 bits (199), Expect = 2e-15
Identities = 71/266 (26%), Positives = 109/266 (40%), Gaps = 24/266 (9%)
Query: 587 SCPEPE-VPSGGYMEAFDYYVHST-INFHCEAGH-KLIGEPNLVCQQDGEWSGDSPTCEY 643
+CP+P+ +P + +Y I + C+ G+ G +C G W ++ C
Sbjct: 22 TCPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYVSRGGMRKFICPLTGLWPINTLKCTP 81
Query: 644 IDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEE 703
C L G + T + I +SC T + L G CTEE +WS P C
Sbjct: 82 RVCPFAGILENGAVRYT--TFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAP 139
Query: 704 IRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGES 763
I C P + + + V S G+ + YR A+ + C + + G
Sbjct: 140 IICPPPSIPTFATLRV--YKPSAGN-----------NSLYRDTAV--FECLPQHAMFGND 184
Query: 764 LSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNAT-FYGATAFYQCDENWELEGV 822
TC +G W+ P C+ V C P R +NG V P+ T +Y A + C + + L+G
Sbjct: 185 TITCTTHGNWT-KLPECREVKCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSLDGP 243
Query: 823 IRRMCQENGTWSLEPPICKEITCPDP 848
C + G WS P CK +C P
Sbjct: 244 EEIECTKLGNWSAMPS-CK-ASCKVP 267
Score = 77.4 bits (182), Expect = 3e-13
Identities = 68/270 (25%), Positives = 103/270 (38%), Gaps = 30/270 (11%)
Query: 646 CGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRR-TCTEEFQWSDSSPRCEEI 704
C K LP+ T+ L G I YSC Y G +R+ C W ++ +C
Sbjct: 23 CPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYVSRGGMRKFICPLTGLWPINTLKCTPR 82
Query: 705 RCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESL 764
C + E V T T+ + + C G+ + G
Sbjct: 83 VCPFAGILENGAVRYT---------------------TFEYPNTISFSCNTGFYLNGADS 121
Query: 765 STCEDNGQWSGTTPTCQYVDCGNPG--RIENGKVTLPS--NATFYGATAFYQCDENWELE 820
+ C + G+WS P C + C P +V PS N + Y TA ++C +
Sbjct: 122 AKCTEEGKWSPELPVCAPIICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMF 181
Query: 821 GVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYN 880
G C +G W+ + P C+E+ CP PS + G TL +A + C GY+
Sbjct: 182 GNDTITCTTHGNWT-KLPECREVKCPFPS-RPDNGFVNYPAKPTLYYKDKATFGCHDGYS 239
Query: 881 LKGHQTRTCISKGQWNGTVPVCIPIDCRSP 910
L G + C G W+ +P C C+ P
Sbjct: 240 LDGPEEIECTKLGNWS-AMPSC-KASCKVP 267
Score = 67.3 bits (157), Expect = 3e-10
Identities = 49/190 (25%), Positives = 73/190 (38%), Gaps = 10/190 (5%)
Query: 350 PPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYV 409
P C L N + ++ + I + C G L G S C ++G WS P C +
Sbjct: 81 PRVCPFAGILENGAVRYTTFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAPI 140
Query: 410 NCGGLTPIEDGDVAL----IDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPR 465
C + + + N + + A++ C + GN TC G W + P
Sbjct: 141 ICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWT-KLPE 199
Query: 466 CLFDWCPDPPAVSNASVTVNGHKA---GSLASYTCENGHILSGSTSVTCTLGGAWSGVPP 522
C CP P N V A++ C +G+ L G + CT G WS + P
Sbjct: 200 CREVKCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSLDGPEEIECTKLGNWSAM-P 258
Query: 523 SCKYVNCGTP 532
SCK +C P
Sbjct: 259 SCK-ASCKVP 267
Score = 43.6 bits (98), Expect = 0.004
Identities = 22/77 (28%), Positives = 36/77 (46%), Gaps = 3/77 (3%)
Query: 1 RCGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGT 60
+C P+ P N V+ P + + A + C +GY L G + ECT G+W+ P
Sbjct: 204 KCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSLDGPEEIECTKLGNWSAMP---SC 260
Query: 61 NVAFRKPANQSTTVRGG 77
+ + P ++T V G
Sbjct: 261 KASCKVPVKKATVVYQG 277
Score = 32.7 bits (71), Expect = 7.4
Identities = 20/57 (35%), Positives = 28/57 (49%), Gaps = 3/57 (5%)
Query: 2 CGHPAVPPNA--RVSIPNE-ENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEP 55
C P++P A RV P+ N + AV+EC + +FG CT G+WT P
Sbjct: 142 CPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWTKLP 198
Score = 32.3 bits (70), Expect = 9.7
Identities = 12/30 (40%), Positives = 17/30 (56%)
Query: 29 YECDEGYELFGARQRECTLRGDWTLEPPFC 58
+ C+ G+ L GA +CT G W+ E P C
Sbjct: 108 FSCNTGFYLNGADSAKCTEEGKWSPELPVC 137
>S51940-1|AAB24802.1| 369|Homo sapiens membrane cofactor protein
protein.
Length = 369
Score = 96.7 bits (230), Expect = 4e-19
Identities = 59/245 (24%), Positives = 101/245 (41%), Gaps = 15/245 (6%)
Query: 369 YDVGSRIVYKCPEGHMLLGDKSRH--CKKDGFWSG-APPSCKYVNCGGLTPIEDGDVALI 425
Y++G R+ YKC +G+ + + H C ++ W + +C C + +G
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA 113
Query: 426 DNRTTHGARALYSCRENFTLVGNPERTC---GDEGIWDGEAPRCLFDWCPDPPAVSNASV 482
+ G + + C E + L+G C G IW G+ P C C PP + N
Sbjct: 114 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKH 173
Query: 483 T---VNGHKAGSLASYTCE-----NGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTI 534
T V + +Y+C+ + L G +++ C WS P CK V C P +
Sbjct: 174 TFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVV 233
Query: 535 HKGSFVLINGTTTY-GSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEV 593
G + G Y + F C+ ++L+G++ +VC+ + W +P C P +
Sbjct: 234 ENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKGPRPTYKP 293
Query: 594 PSGGY 598
P Y
Sbjct: 294 PVSNY 298
Score = 90.6 bits (215), Expect = 3e-17
Identities = 53/171 (30%), Positives = 75/171 (43%), Gaps = 11/171 (6%)
Query: 742 TYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTCQYVDCGNPGRIENGKVTL 798
TY G + + C +GY +IGE + CE G WSG P C+ V C P +I+NGK T
Sbjct: 116 TYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTF 175
Query: 799 PSNATF-YGATAFYQCD-----ENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQI 852
F Y Y CD + + L G C +N WS P CK + C P +
Sbjct: 176 SEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPV--V 233
Query: 853 KAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCI 903
+ G + ++C++G+ L G T C S W+ VP C+
Sbjct: 234 ENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCL 284
Score = 84.2 bits (199), Expect = 2e-15
Identities = 60/229 (26%), Positives = 91/229 (39%), Gaps = 21/229 (9%)
Query: 432 GARALYSCRENFTLVGN--PERTCGDEGIW-DGEAPRCLFDWCP---DPPAVSNASVTVN 485
G R Y C++ + + C W C + CP DP ++ +V N
Sbjct: 57 GERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDP--LNGQAVPAN 114
Query: 486 G-HKAGSLASYTCENGHILSGSTSVTCTLGGA---WSGVPPSCKYVNCGTPT-IHKGSFV 540
G ++ G + C G+ L G + C L G+ WSG PP C+ V C P I G
Sbjct: 115 GTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHT 174
Query: 541 LINGTT-TYGSIAQFTCEP-----DYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVP 594
Y ++C+P + L G + C + WS P C++ C P V
Sbjct: 175 FSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVE 234
Query: 595 SGGYMEAFD--YYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTC 641
+G + F +Y +T+ F C+ G L G +VC + W P C
Sbjct: 235 NGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 81.0 bits (191), Expect = 2e-14
Identities = 65/258 (25%), Positives = 106/258 (41%), Gaps = 33/258 (12%)
Query: 604 YYVHSTINFHCEAGHKLIGE--PNLVCQQDGEWSGDSPTCEYID-CGKLPTLPYGTMELL 660
Y + +++ C+ G+ I + +C ++ W S Y + C + G
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA 113
Query: 661 NGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQ---WSDSSPRCEEIRCSDPIVAEKSIV 717
NGT G + + C Y L+G C + WS P CE++ C+ P +
Sbjct: 114 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNG-- 171
Query: 718 SVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKG-----YKVIGESLSTCEDNGQ 772
H + + + D V Y C+ + +IGES C DN
Sbjct: 172 -------KHTFSEVEVFEYLDA---------VTYSCDPAPGPDPFSLIGESTIYCGDNSV 215
Query: 773 WSGTTPTCQYVDCGNPGRIENGK-VTLPSNATFYGATAFYQCDENWELEGVIRRMCQENG 831
WS P C+ V C P +ENGK ++ +Y AT ++CD+ + L+G +C N
Sbjct: 216 WSRAAPECKVVKCRFPV-VENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNS 274
Query: 832 TWSLEPPICKEITCPDPS 849
TW +PP+ K + P P+
Sbjct: 275 TW--DPPVPKCLKGPRPT 290
Score = 81.0 bits (191), Expect = 2e-14
Identities = 62/233 (26%), Positives = 96/233 (41%), Gaps = 16/233 (6%)
Query: 743 YRIGALVKYRCEKGYKVIG--ESLSTCEDNGQWSGTT-PTCQYVDCGNPGRIENGKVTLP 799
Y IG V Y+C+KGY I + + C+ N W + C C NG+ +P
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQ-AVP 112
Query: 800 SNATF-YGATAFYQCDENWELEGVIRRMCQENGT---WSLEPPICKEITCPDPSAQIKAG 855
+N T+ +G + C+E + L G C+ G+ WS +PPIC+++ C P +IK G
Sbjct: 113 ANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLC-TPPPKIKNG 171
Query: 856 SGLLVVTSTLSIGGEAHYQCERG-----YNLKGHQTRTCISKGQWNGTVPVCIPIDCRSP 910
Y C+ ++L G T C W+ P C + CR P
Sbjct: 172 KHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFP 231
Query: 911 GNIENGKIVISNGSTL-FGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
+ENGK + G + ++V + C + G C + W P C
Sbjct: 232 -VVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 77.8 bits (183), Expect = 2e-13
Identities = 65/256 (25%), Positives = 97/256 (37%), Gaps = 28/256 (10%)
Query: 469 DWCPDPPAVSNASVTVNG---HKAGSLASYTCENGH--ILSGSTSVTCTLGGAWSGVPP- 522
D C +PP + ++ G Y C+ G+ I +T C W V
Sbjct: 33 DACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDD 92
Query: 523 SCKYVNCGTPTIH---KGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGK---W 576
+C C P I G V NGT +G F C Y+L G E L C G W
Sbjct: 93 ACYRETC--PYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIW 150
Query: 577 SYDIPSCELTSC-PEPEVPSGGY----MEAFDYYVHSTINFHCEAG-----HKLIGEPNL 626
S P CE C P P++ +G + +E F+Y + + C+ LIGE +
Sbjct: 151 SGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYL--DAVTYSCDPAPGPDPFSLIGESTI 208
Query: 627 VCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTT-HLGSVIQYSCTTNYRLVGPVR 685
C + WS +P C+ + C + P + G G + + + + C + L G
Sbjct: 209 YCGDNSVWSRAAPECKVVKC-RFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDT 267
Query: 686 RTCTEEFQWSDSSPRC 701
C W P+C
Sbjct: 268 IVCDSNSTWDPPVPKC 283
Score = 76.2 bits (179), Expect = 6e-13
Identities = 66/252 (26%), Positives = 100/252 (39%), Gaps = 45/252 (17%)
Query: 549 GSIAQFTCEPDYWLNG--AEELVCNRDGKW-SYDIPSCELTSCP---EP----EVPSGGY 598
G + C+ Y+ A +C+R+ W +C +CP +P VP+ G
Sbjct: 57 GERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGT 116
Query: 599 MEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGE---WSGDSPTCEYIDCGKLPTLPYG 655
E F Y +H F C G+ LIGE L C+ G WSG P CE + C P + G
Sbjct: 117 YE-FGYQMH----FICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNG 171
Query: 656 --TMELLNGTTHLGSVIQYSCTTN-----YRLVGPVRRTCTEEFQWSDSSPRCEEIRCSD 708
T + +L +V YSC + L+G C + WS ++P C+ ++C
Sbjct: 172 KHTFSEVEVFEYLDAVT-YSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRF 230
Query: 709 PIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCE 768
P+V +S G + A V + C+KG+ + G C+
Sbjct: 231 PVVENGKQIS-------------------GFGKKFYYKATVMFECDKGFYLDGSDTIVCD 271
Query: 769 DNGQWSGTTPTC 780
N W P C
Sbjct: 272 SNSTWDPPVPKC 283
Score = 60.9 bits (141), Expect = 2e-08
Identities = 40/149 (26%), Positives = 59/149 (39%), Gaps = 12/149 (8%)
Query: 826 MCQENGTW-SLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGH 884
+C N TW + C TCP + + + T G + H+ C GY L G
Sbjct: 79 ICDRNHTWLPVSDDACYRETCPYIRDPLNGQA--VPANGTYEFGYQMHFICNEGYYLIGE 136
Query: 885 QTRTCISKGQ---WNGTVPVCIPIDCRSPGNIENGKIVISNGSTL-FGSSVEYYC----- 935
+ C KG W+G P+C + C P I+NGK S + +V Y C
Sbjct: 137 EILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPG 196
Query: 936 LSQYQRVGPFLRKCLDDGRWSGEEPSCEL 964
+ +G C D+ WS P C++
Sbjct: 197 PDPFSLIGESTIYCGDNSVWSRAAPECKV 225
>EF076056-1|ABK81636.1| 369|Homo sapiens CD46 protein.
Length = 369
Score = 96.7 bits (230), Expect = 4e-19
Identities = 59/245 (24%), Positives = 101/245 (41%), Gaps = 15/245 (6%)
Query: 369 YDVGSRIVYKCPEGHMLLGDKSRH--CKKDGFWSG-APPSCKYVNCGGLTPIEDGDVALI 425
Y++G R+ YKC +G+ + + H C ++ W + +C C + +G
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA 113
Query: 426 DNRTTHGARALYSCRENFTLVGNPERTC---GDEGIWDGEAPRCLFDWCPDPPAVSNASV 482
+ G + + C E + L+G C G IW G+ P C C PP + N
Sbjct: 114 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKH 173
Query: 483 T---VNGHKAGSLASYTCE-----NGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTI 534
T V + +Y+C+ + L G +++ C WS P CK V C P +
Sbjct: 174 TFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVV 233
Query: 535 HKGSFVLINGTTTY-GSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEV 593
G + G Y + F C+ ++L+G++ +VC+ + W +P C P +
Sbjct: 234 ENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKGPRPTYKP 293
Query: 594 PSGGY 598
P Y
Sbjct: 294 PVSNY 298
Score = 90.6 bits (215), Expect = 3e-17
Identities = 53/171 (30%), Positives = 75/171 (43%), Gaps = 11/171 (6%)
Query: 742 TYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTCQYVDCGNPGRIENGKVTL 798
TY G + + C +GY +IGE + CE G WSG P C+ V C P +I+NGK T
Sbjct: 116 TYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTF 175
Query: 799 PSNATF-YGATAFYQCD-----ENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQI 852
F Y Y CD + + L G C +N WS P CK + C P +
Sbjct: 176 SEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPV--V 233
Query: 853 KAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCI 903
+ G + ++C++G+ L G T C S W+ VP C+
Sbjct: 234 ENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCL 284
Score = 84.2 bits (199), Expect = 2e-15
Identities = 60/229 (26%), Positives = 91/229 (39%), Gaps = 21/229 (9%)
Query: 432 GARALYSCRENFTLVGN--PERTCGDEGIW-DGEAPRCLFDWCP---DPPAVSNASVTVN 485
G R Y C++ + + C W C + CP DP ++ +V N
Sbjct: 57 GERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDP--LNGQAVPAN 114
Query: 486 G-HKAGSLASYTCENGHILSGSTSVTCTLGGA---WSGVPPSCKYVNCGTPT-IHKGSFV 540
G ++ G + C G+ L G + C L G+ WSG PP C+ V C P I G
Sbjct: 115 GTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHT 174
Query: 541 LINGTT-TYGSIAQFTCEP-----DYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVP 594
Y ++C+P + L G + C + WS P C++ C P V
Sbjct: 175 FSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVE 234
Query: 595 SGGYMEAFD--YYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTC 641
+G + F +Y +T+ F C+ G L G +VC + W P C
Sbjct: 235 NGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 81.0 bits (191), Expect = 2e-14
Identities = 65/258 (25%), Positives = 106/258 (41%), Gaps = 33/258 (12%)
Query: 604 YYVHSTINFHCEAGHKLIGE--PNLVCQQDGEWSGDSPTCEYID-CGKLPTLPYGTMELL 660
Y + +++ C+ G+ I + +C ++ W S Y + C + G
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA 113
Query: 661 NGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQ---WSDSSPRCEEIRCSDPIVAEKSIV 717
NGT G + + C Y L+G C + WS P CE++ C+ P +
Sbjct: 114 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNG-- 171
Query: 718 SVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKG-----YKVIGESLSTCEDNGQ 772
H + + + D V Y C+ + +IGES C DN
Sbjct: 172 -------KHTFSEVEVFEYLDA---------VTYSCDPAPGPDPFSLIGESTIYCGDNSV 215
Query: 773 WSGTTPTCQYVDCGNPGRIENGK-VTLPSNATFYGATAFYQCDENWELEGVIRRMCQENG 831
WS P C+ V C P +ENGK ++ +Y AT ++CD+ + L+G +C N
Sbjct: 216 WSRAAPECKVVKCRFPV-VENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNS 274
Query: 832 TWSLEPPICKEITCPDPS 849
TW +PP+ K + P P+
Sbjct: 275 TW--DPPVPKCLKGPRPT 290
Score = 81.0 bits (191), Expect = 2e-14
Identities = 62/233 (26%), Positives = 96/233 (41%), Gaps = 16/233 (6%)
Query: 743 YRIGALVKYRCEKGYKVIG--ESLSTCEDNGQWSGTT-PTCQYVDCGNPGRIENGKVTLP 799
Y IG V Y+C+KGY I + + C+ N W + C C NG+ +P
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQ-AVP 112
Query: 800 SNATF-YGATAFYQCDENWELEGVIRRMCQENGT---WSLEPPICKEITCPDPSAQIKAG 855
+N T+ +G + C+E + L G C+ G+ WS +PPIC+++ C P +IK G
Sbjct: 113 ANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLC-TPPPKIKNG 171
Query: 856 SGLLVVTSTLSIGGEAHYQCERG-----YNLKGHQTRTCISKGQWNGTVPVCIPIDCRSP 910
Y C+ ++L G T C W+ P C + CR P
Sbjct: 172 KHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFP 231
Query: 911 GNIENGKIVISNGSTL-FGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
+ENGK + G + ++V + C + G C + W P C
Sbjct: 232 -VVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 77.8 bits (183), Expect = 2e-13
Identities = 65/256 (25%), Positives = 97/256 (37%), Gaps = 28/256 (10%)
Query: 469 DWCPDPPAVSNASVTVNG---HKAGSLASYTCENGH--ILSGSTSVTCTLGGAWSGVPP- 522
D C +PP + ++ G Y C+ G+ I +T C W V
Sbjct: 33 DACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDD 92
Query: 523 SCKYVNCGTPTIH---KGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGK---W 576
+C C P I G V NGT +G F C Y+L G E L C G W
Sbjct: 93 ACYRETC--PYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIW 150
Query: 577 SYDIPSCELTSC-PEPEVPSGGY----MEAFDYYVHSTINFHCEAG-----HKLIGEPNL 626
S P CE C P P++ +G + +E F+Y + + C+ LIGE +
Sbjct: 151 SGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYL--DAVTYSCDPAPGPDPFSLIGESTI 208
Query: 627 VCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTT-HLGSVIQYSCTTNYRLVGPVR 685
C + WS +P C+ + C + P + G G + + + + C + L G
Sbjct: 209 YCGDNSVWSRAAPECKVVKC-RFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDT 267
Query: 686 RTCTEEFQWSDSSPRC 701
C W P+C
Sbjct: 268 IVCDSNSTWDPPVPKC 283
Score = 76.2 bits (179), Expect = 6e-13
Identities = 66/252 (26%), Positives = 100/252 (39%), Gaps = 45/252 (17%)
Query: 549 GSIAQFTCEPDYWLNG--AEELVCNRDGKW-SYDIPSCELTSCP---EP----EVPSGGY 598
G + C+ Y+ A +C+R+ W +C +CP +P VP+ G
Sbjct: 57 GERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGT 116
Query: 599 MEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGE---WSGDSPTCEYIDCGKLPTLPYG 655
E F Y +H F C G+ LIGE L C+ G WSG P CE + C P + G
Sbjct: 117 YE-FGYQMH----FICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNG 171
Query: 656 --TMELLNGTTHLGSVIQYSCTTN-----YRLVGPVRRTCTEEFQWSDSSPRCEEIRCSD 708
T + +L +V YSC + L+G C + WS ++P C+ ++C
Sbjct: 172 KHTFSEVEVFEYLDAVT-YSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRF 230
Query: 709 PIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCE 768
P+V +S G + A V + C+KG+ + G C+
Sbjct: 231 PVVENGKQIS-------------------GFGKKFYYKATVMFECDKGFYLDGSDTIVCD 271
Query: 769 DNGQWSGTTPTC 780
N W P C
Sbjct: 272 SNSTWDPPVPKC 283
Score = 60.9 bits (141), Expect = 2e-08
Identities = 40/149 (26%), Positives = 59/149 (39%), Gaps = 12/149 (8%)
Query: 826 MCQENGTW-SLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGH 884
+C N TW + C TCP + + + T G + H+ C GY L G
Sbjct: 79 ICDRNHTWLPVSDDACYRETCPYIRDPLNGQA--VPANGTYEFGYQMHFICNEGYYLIGE 136
Query: 885 QTRTCISKGQ---WNGTVPVCIPIDCRSPGNIENGKIVISNGSTL-FGSSVEYYC----- 935
+ C KG W+G P+C + C P I+NGK S + +V Y C
Sbjct: 137 EILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPG 196
Query: 936 LSQYQRVGPFLRKCLDDGRWSGEEPSCEL 964
+ +G C D+ WS P C++
Sbjct: 197 PDPFSLIGESTIYCGDNSVWSRAAPECKV 225
>D84105-1|BAA12224.1| 349|Homo sapiens CD46 protein.
Length = 349
Score = 96.7 bits (230), Expect = 4e-19
Identities = 59/245 (24%), Positives = 101/245 (41%), Gaps = 15/245 (6%)
Query: 369 YDVGSRIVYKCPEGHMLLGDKSRH--CKKDGFWSG-APPSCKYVNCGGLTPIEDGDVALI 425
Y++G R+ YKC +G+ + + H C ++ W + +C C + +G
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA 113
Query: 426 DNRTTHGARALYSCRENFTLVGNPERTC---GDEGIWDGEAPRCLFDWCPDPPAVSNASV 482
+ G + + C E + L+G C G IW G+ P C C PP + N
Sbjct: 114 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKH 173
Query: 483 T---VNGHKAGSLASYTCE-----NGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTI 534
T V + +Y+C+ + L G +++ C WS P CK V C P +
Sbjct: 174 TFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVV 233
Query: 535 HKGSFVLINGTTTY-GSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEV 593
G + G Y + F C+ ++L+G++ +VC+ + W +P C P +
Sbjct: 234 ENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKGPRPTYKP 293
Query: 594 PSGGY 598
P Y
Sbjct: 294 PVSNY 298
Score = 90.6 bits (215), Expect = 3e-17
Identities = 53/171 (30%), Positives = 75/171 (43%), Gaps = 11/171 (6%)
Query: 742 TYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTCQYVDCGNPGRIENGKVTL 798
TY G + + C +GY +IGE + CE G WSG P C+ V C P +I+NGK T
Sbjct: 116 TYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTF 175
Query: 799 PSNATF-YGATAFYQCD-----ENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQI 852
F Y Y CD + + L G C +N WS P CK + C P +
Sbjct: 176 SEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPV--V 233
Query: 853 KAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCI 903
+ G + ++C++G+ L G T C S W+ VP C+
Sbjct: 234 ENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCL 284
Score = 84.2 bits (199), Expect = 2e-15
Identities = 60/229 (26%), Positives = 91/229 (39%), Gaps = 21/229 (9%)
Query: 432 GARALYSCRENFTLVGN--PERTCGDEGIW-DGEAPRCLFDWCP---DPPAVSNASVTVN 485
G R Y C++ + + C W C + CP DP ++ +V N
Sbjct: 57 GERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDP--LNGQAVPAN 114
Query: 486 G-HKAGSLASYTCENGHILSGSTSVTCTLGGA---WSGVPPSCKYVNCGTPT-IHKGSFV 540
G ++ G + C G+ L G + C L G+ WSG PP C+ V C P I G
Sbjct: 115 GTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHT 174
Query: 541 LINGTT-TYGSIAQFTCEP-----DYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVP 594
Y ++C+P + L G + C + WS P C++ C P V
Sbjct: 175 FSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVE 234
Query: 595 SGGYMEAFD--YYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTC 641
+G + F +Y +T+ F C+ G L G +VC + W P C
Sbjct: 235 NGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 81.0 bits (191), Expect = 2e-14
Identities = 65/258 (25%), Positives = 106/258 (41%), Gaps = 33/258 (12%)
Query: 604 YYVHSTINFHCEAGHKLIGE--PNLVCQQDGEWSGDSPTCEYID-CGKLPTLPYGTMELL 660
Y + +++ C+ G+ I + +C ++ W S Y + C + G
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA 113
Query: 661 NGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQ---WSDSSPRCEEIRCSDPIVAEKSIV 717
NGT G + + C Y L+G C + WS P CE++ C+ P +
Sbjct: 114 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNG-- 171
Query: 718 SVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKG-----YKVIGESLSTCEDNGQ 772
H + + + D V Y C+ + +IGES C DN
Sbjct: 172 -------KHTFSEVEVFEYLDA---------VTYSCDPAPGPDPFSLIGESTIYCGDNSV 215
Query: 773 WSGTTPTCQYVDCGNPGRIENGK-VTLPSNATFYGATAFYQCDENWELEGVIRRMCQENG 831
WS P C+ V C P +ENGK ++ +Y AT ++CD+ + L+G +C N
Sbjct: 216 WSRAAPECKVVKCRFPV-VENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNS 274
Query: 832 TWSLEPPICKEITCPDPS 849
TW +PP+ K + P P+
Sbjct: 275 TW--DPPVPKCLKGPRPT 290
Score = 81.0 bits (191), Expect = 2e-14
Identities = 62/233 (26%), Positives = 96/233 (41%), Gaps = 16/233 (6%)
Query: 743 YRIGALVKYRCEKGYKVIG--ESLSTCEDNGQWSGTT-PTCQYVDCGNPGRIENGKVTLP 799
Y IG V Y+C+KGY I + + C+ N W + C C NG+ +P
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQ-AVP 112
Query: 800 SNATF-YGATAFYQCDENWELEGVIRRMCQENGT---WSLEPPICKEITCPDPSAQIKAG 855
+N T+ +G + C+E + L G C+ G+ WS +PPIC+++ C P +IK G
Sbjct: 113 ANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLC-TPPPKIKNG 171
Query: 856 SGLLVVTSTLSIGGEAHYQCERG-----YNLKGHQTRTCISKGQWNGTVPVCIPIDCRSP 910
Y C+ ++L G T C W+ P C + CR P
Sbjct: 172 KHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFP 231
Query: 911 GNIENGKIVISNGSTL-FGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
+ENGK + G + ++V + C + G C + W P C
Sbjct: 232 -VVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 77.8 bits (183), Expect = 2e-13
Identities = 65/256 (25%), Positives = 97/256 (37%), Gaps = 28/256 (10%)
Query: 469 DWCPDPPAVSNASVTVNG---HKAGSLASYTCENGH--ILSGSTSVTCTLGGAWSGVPP- 522
D C +PP + ++ G Y C+ G+ I +T C W V
Sbjct: 33 DACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDD 92
Query: 523 SCKYVNCGTPTIH---KGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGK---W 576
+C C P I G V NGT +G F C Y+L G E L C G W
Sbjct: 93 ACYRETC--PYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIW 150
Query: 577 SYDIPSCELTSC-PEPEVPSGGY----MEAFDYYVHSTINFHCEAG-----HKLIGEPNL 626
S P CE C P P++ +G + +E F+Y + + C+ LIGE +
Sbjct: 151 SGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYL--DAVTYSCDPAPGPDPFSLIGESTI 208
Query: 627 VCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTT-HLGSVIQYSCTTNYRLVGPVR 685
C + WS +P C+ + C + P + G G + + + + C + L G
Sbjct: 209 YCGDNSVWSRAAPECKVVKC-RFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDT 267
Query: 686 RTCTEEFQWSDSSPRC 701
C W P+C
Sbjct: 268 IVCDSNSTWDPPVPKC 283
Score = 76.2 bits (179), Expect = 6e-13
Identities = 66/252 (26%), Positives = 100/252 (39%), Gaps = 45/252 (17%)
Query: 549 GSIAQFTCEPDYWLNG--AEELVCNRDGKW-SYDIPSCELTSCP---EP----EVPSGGY 598
G + C+ Y+ A +C+R+ W +C +CP +P VP+ G
Sbjct: 57 GERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGT 116
Query: 599 MEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGE---WSGDSPTCEYIDCGKLPTLPYG 655
E F Y +H F C G+ LIGE L C+ G WSG P CE + C P + G
Sbjct: 117 YE-FGYQMH----FICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNG 171
Query: 656 --TMELLNGTTHLGSVIQYSCTTN-----YRLVGPVRRTCTEEFQWSDSSPRCEEIRCSD 708
T + +L +V YSC + L+G C + WS ++P C+ ++C
Sbjct: 172 KHTFSEVEVFEYLDAVT-YSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRF 230
Query: 709 PIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCE 768
P+V +S G + A V + C+KG+ + G C+
Sbjct: 231 PVVENGKQIS-------------------GFGKKFYYKATVMFECDKGFYLDGSDTIVCD 271
Query: 769 DNGQWSGTTPTC 780
N W P C
Sbjct: 272 SNSTWDPPVPKC 283
Score = 60.9 bits (141), Expect = 2e-08
Identities = 40/149 (26%), Positives = 59/149 (39%), Gaps = 12/149 (8%)
Query: 826 MCQENGTW-SLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGH 884
+C N TW + C TCP + + + T G + H+ C GY L G
Sbjct: 79 ICDRNHTWLPVSDDACYRETCPYIRDPLNGQA--VPANGTYEFGYQMHFICNEGYYLIGE 136
Query: 885 QTRTCISKGQ---WNGTVPVCIPIDCRSPGNIENGKIVISNGSTL-FGSSVEYYC----- 935
+ C KG W+G P+C + C P I+NGK S + +V Y C
Sbjct: 137 EILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPG 196
Query: 936 LSQYQRVGPFLRKCLDDGRWSGEEPSCEL 964
+ +G C D+ WS P C++
Sbjct: 197 PDPFSLIGESTIYCGDNSVWSRAAPECKV 225
>AL365178-8|CAH73954.1| 349|Homo sapiens CD46 molecule, complement
regulatory protein protein.
Length = 349
Score = 96.7 bits (230), Expect = 4e-19
Identities = 59/245 (24%), Positives = 101/245 (41%), Gaps = 15/245 (6%)
Query: 369 YDVGSRIVYKCPEGHMLLGDKSRH--CKKDGFWSG-APPSCKYVNCGGLTPIEDGDVALI 425
Y++G R+ YKC +G+ + + H C ++ W + +C C + +G
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA 113
Query: 426 DNRTTHGARALYSCRENFTLVGNPERTC---GDEGIWDGEAPRCLFDWCPDPPAVSNASV 482
+ G + + C E + L+G C G IW G+ P C C PP + N
Sbjct: 114 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKH 173
Query: 483 T---VNGHKAGSLASYTCE-----NGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTI 534
T V + +Y+C+ + L G +++ C WS P CK V C P +
Sbjct: 174 TFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVV 233
Query: 535 HKGSFVLINGTTTY-GSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEV 593
G + G Y + F C+ ++L+G++ +VC+ + W +P C P +
Sbjct: 234 ENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKGPRPTYKP 293
Query: 594 PSGGY 598
P Y
Sbjct: 294 PVSNY 298
Score = 90.6 bits (215), Expect = 3e-17
Identities = 53/171 (30%), Positives = 75/171 (43%), Gaps = 11/171 (6%)
Query: 742 TYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTCQYVDCGNPGRIENGKVTL 798
TY G + + C +GY +IGE + CE G WSG P C+ V C P +I+NGK T
Sbjct: 116 TYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTF 175
Query: 799 PSNATF-YGATAFYQCD-----ENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQI 852
F Y Y CD + + L G C +N WS P CK + C P +
Sbjct: 176 SEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPV--V 233
Query: 853 KAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCI 903
+ G + ++C++G+ L G T C S W+ VP C+
Sbjct: 234 ENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCL 284
Score = 84.2 bits (199), Expect = 2e-15
Identities = 60/229 (26%), Positives = 91/229 (39%), Gaps = 21/229 (9%)
Query: 432 GARALYSCRENFTLVGN--PERTCGDEGIW-DGEAPRCLFDWCP---DPPAVSNASVTVN 485
G R Y C++ + + C W C + CP DP ++ +V N
Sbjct: 57 GERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDP--LNGQAVPAN 114
Query: 486 G-HKAGSLASYTCENGHILSGSTSVTCTLGGA---WSGVPPSCKYVNCGTPT-IHKGSFV 540
G ++ G + C G+ L G + C L G+ WSG PP C+ V C P I G
Sbjct: 115 GTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHT 174
Query: 541 LINGTT-TYGSIAQFTCEP-----DYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVP 594
Y ++C+P + L G + C + WS P C++ C P V
Sbjct: 175 FSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVE 234
Query: 595 SGGYMEAFD--YYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTC 641
+G + F +Y +T+ F C+ G L G +VC + W P C
Sbjct: 235 NGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 81.0 bits (191), Expect = 2e-14
Identities = 65/258 (25%), Positives = 106/258 (41%), Gaps = 33/258 (12%)
Query: 604 YYVHSTINFHCEAGHKLIGE--PNLVCQQDGEWSGDSPTCEYID-CGKLPTLPYGTMELL 660
Y + +++ C+ G+ I + +C ++ W S Y + C + G
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA 113
Query: 661 NGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQ---WSDSSPRCEEIRCSDPIVAEKSIV 717
NGT G + + C Y L+G C + WS P CE++ C+ P +
Sbjct: 114 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNG-- 171
Query: 718 SVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKG-----YKVIGESLSTCEDNGQ 772
H + + + D V Y C+ + +IGES C DN
Sbjct: 172 -------KHTFSEVEVFEYLDA---------VTYSCDPAPGPDPFSLIGESTIYCGDNSV 215
Query: 773 WSGTTPTCQYVDCGNPGRIENGK-VTLPSNATFYGATAFYQCDENWELEGVIRRMCQENG 831
WS P C+ V C P +ENGK ++ +Y AT ++CD+ + L+G +C N
Sbjct: 216 WSRAAPECKVVKCRFPV-VENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNS 274
Query: 832 TWSLEPPICKEITCPDPS 849
TW +PP+ K + P P+
Sbjct: 275 TW--DPPVPKCLKGPRPT 290
Score = 81.0 bits (191), Expect = 2e-14
Identities = 62/233 (26%), Positives = 96/233 (41%), Gaps = 16/233 (6%)
Query: 743 YRIGALVKYRCEKGYKVIG--ESLSTCEDNGQWSGTT-PTCQYVDCGNPGRIENGKVTLP 799
Y IG V Y+C+KGY I + + C+ N W + C C NG+ +P
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQ-AVP 112
Query: 800 SNATF-YGATAFYQCDENWELEGVIRRMCQENGT---WSLEPPICKEITCPDPSAQIKAG 855
+N T+ +G + C+E + L G C+ G+ WS +PPIC+++ C P +IK G
Sbjct: 113 ANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLC-TPPPKIKNG 171
Query: 856 SGLLVVTSTLSIGGEAHYQCERG-----YNLKGHQTRTCISKGQWNGTVPVCIPIDCRSP 910
Y C+ ++L G T C W+ P C + CR P
Sbjct: 172 KHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFP 231
Query: 911 GNIENGKIVISNGSTL-FGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
+ENGK + G + ++V + C + G C + W P C
Sbjct: 232 -VVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 77.8 bits (183), Expect = 2e-13
Identities = 65/256 (25%), Positives = 97/256 (37%), Gaps = 28/256 (10%)
Query: 469 DWCPDPPAVSNASVTVNG---HKAGSLASYTCENGH--ILSGSTSVTCTLGGAWSGVPP- 522
D C +PP + ++ G Y C+ G+ I +T C W V
Sbjct: 33 DACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDD 92
Query: 523 SCKYVNCGTPTIH---KGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGK---W 576
+C C P I G V NGT +G F C Y+L G E L C G W
Sbjct: 93 ACYRETC--PYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIW 150
Query: 577 SYDIPSCELTSC-PEPEVPSGGY----MEAFDYYVHSTINFHCEAG-----HKLIGEPNL 626
S P CE C P P++ +G + +E F+Y + + C+ LIGE +
Sbjct: 151 SGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYL--DAVTYSCDPAPGPDPFSLIGESTI 208
Query: 627 VCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTT-HLGSVIQYSCTTNYRLVGPVR 685
C + WS +P C+ + C + P + G G + + + + C + L G
Sbjct: 209 YCGDNSVWSRAAPECKVVKC-RFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDT 267
Query: 686 RTCTEEFQWSDSSPRC 701
C W P+C
Sbjct: 268 IVCDSNSTWDPPVPKC 283
Score = 76.2 bits (179), Expect = 6e-13
Identities = 66/252 (26%), Positives = 100/252 (39%), Gaps = 45/252 (17%)
Query: 549 GSIAQFTCEPDYWLNG--AEELVCNRDGKW-SYDIPSCELTSCP---EP----EVPSGGY 598
G + C+ Y+ A +C+R+ W +C +CP +P VP+ G
Sbjct: 57 GERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGT 116
Query: 599 MEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGE---WSGDSPTCEYIDCGKLPTLPYG 655
E F Y +H F C G+ LIGE L C+ G WSG P CE + C P + G
Sbjct: 117 YE-FGYQMH----FICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNG 171
Query: 656 --TMELLNGTTHLGSVIQYSCTTN-----YRLVGPVRRTCTEEFQWSDSSPRCEEIRCSD 708
T + +L +V YSC + L+G C + WS ++P C+ ++C
Sbjct: 172 KHTFSEVEVFEYLDAVT-YSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRF 230
Query: 709 PIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCE 768
P+V +S G + A V + C+KG+ + G C+
Sbjct: 231 PVVENGKQIS-------------------GFGKKFYYKATVMFECDKGFYLDGSDTIVCD 271
Query: 769 DNGQWSGTTPTC 780
N W P C
Sbjct: 272 SNSTWDPPVPKC 283
Score = 60.9 bits (141), Expect = 2e-08
Identities = 40/149 (26%), Positives = 59/149 (39%), Gaps = 12/149 (8%)
Query: 826 MCQENGTW-SLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGH 884
+C N TW + C TCP + + + T G + H+ C GY L G
Sbjct: 79 ICDRNHTWLPVSDDACYRETCPYIRDPLNGQA--VPANGTYEFGYQMHFICNEGYYLIGE 136
Query: 885 QTRTCISKGQ---WNGTVPVCIPIDCRSPGNIENGKIVISNGSTL-FGSSVEYYC----- 935
+ C KG W+G P+C + C P I+NGK S + +V Y C
Sbjct: 137 EILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPG 196
Query: 936 LSQYQRVGPFLRKCLDDGRWSGEEPSCEL 964
+ +G C D+ WS P C++
Sbjct: 197 PDPFSLIGESTIYCGDNSVWSRAAPECKV 225
>AL365178-6|CAH73953.1| 369|Homo sapiens CD46 molecule, complement
regulatory protein protein.
Length = 369
Score = 96.7 bits (230), Expect = 4e-19
Identities = 59/245 (24%), Positives = 101/245 (41%), Gaps = 15/245 (6%)
Query: 369 YDVGSRIVYKCPEGHMLLGDKSRH--CKKDGFWSG-APPSCKYVNCGGLTPIEDGDVALI 425
Y++G R+ YKC +G+ + + H C ++ W + +C C + +G
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA 113
Query: 426 DNRTTHGARALYSCRENFTLVGNPERTC---GDEGIWDGEAPRCLFDWCPDPPAVSNASV 482
+ G + + C E + L+G C G IW G+ P C C PP + N
Sbjct: 114 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKH 173
Query: 483 T---VNGHKAGSLASYTCE-----NGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTI 534
T V + +Y+C+ + L G +++ C WS P CK V C P +
Sbjct: 174 TFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVV 233
Query: 535 HKGSFVLINGTTTY-GSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEV 593
G + G Y + F C+ ++L+G++ +VC+ + W +P C P +
Sbjct: 234 ENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKGPRPTYKP 293
Query: 594 PSGGY 598
P Y
Sbjct: 294 PVSNY 298
Score = 90.6 bits (215), Expect = 3e-17
Identities = 53/171 (30%), Positives = 75/171 (43%), Gaps = 11/171 (6%)
Query: 742 TYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTCQYVDCGNPGRIENGKVTL 798
TY G + + C +GY +IGE + CE G WSG P C+ V C P +I+NGK T
Sbjct: 116 TYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTF 175
Query: 799 PSNATF-YGATAFYQCD-----ENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQI 852
F Y Y CD + + L G C +N WS P CK + C P +
Sbjct: 176 SEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPV--V 233
Query: 853 KAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCI 903
+ G + ++C++G+ L G T C S W+ VP C+
Sbjct: 234 ENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCL 284
Score = 84.2 bits (199), Expect = 2e-15
Identities = 60/229 (26%), Positives = 91/229 (39%), Gaps = 21/229 (9%)
Query: 432 GARALYSCRENFTLVGN--PERTCGDEGIW-DGEAPRCLFDWCP---DPPAVSNASVTVN 485
G R Y C++ + + C W C + CP DP ++ +V N
Sbjct: 57 GERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDP--LNGQAVPAN 114
Query: 486 G-HKAGSLASYTCENGHILSGSTSVTCTLGGA---WSGVPPSCKYVNCGTPT-IHKGSFV 540
G ++ G + C G+ L G + C L G+ WSG PP C+ V C P I G
Sbjct: 115 GTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHT 174
Query: 541 LINGTT-TYGSIAQFTCEP-----DYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVP 594
Y ++C+P + L G + C + WS P C++ C P V
Sbjct: 175 FSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVE 234
Query: 595 SGGYMEAFD--YYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTC 641
+G + F +Y +T+ F C+ G L G +VC + W P C
Sbjct: 235 NGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 81.0 bits (191), Expect = 2e-14
Identities = 65/258 (25%), Positives = 106/258 (41%), Gaps = 33/258 (12%)
Query: 604 YYVHSTINFHCEAGHKLIGE--PNLVCQQDGEWSGDSPTCEYID-CGKLPTLPYGTMELL 660
Y + +++ C+ G+ I + +C ++ W S Y + C + G
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA 113
Query: 661 NGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQ---WSDSSPRCEEIRCSDPIVAEKSIV 717
NGT G + + C Y L+G C + WS P CE++ C+ P +
Sbjct: 114 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNG-- 171
Query: 718 SVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKG-----YKVIGESLSTCEDNGQ 772
H + + + D V Y C+ + +IGES C DN
Sbjct: 172 -------KHTFSEVEVFEYLDA---------VTYSCDPAPGPDPFSLIGESTIYCGDNSV 215
Query: 773 WSGTTPTCQYVDCGNPGRIENGK-VTLPSNATFYGATAFYQCDENWELEGVIRRMCQENG 831
WS P C+ V C P +ENGK ++ +Y AT ++CD+ + L+G +C N
Sbjct: 216 WSRAAPECKVVKCRFPV-VENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNS 274
Query: 832 TWSLEPPICKEITCPDPS 849
TW +PP+ K + P P+
Sbjct: 275 TW--DPPVPKCLKGPRPT 290
Score = 81.0 bits (191), Expect = 2e-14
Identities = 62/233 (26%), Positives = 96/233 (41%), Gaps = 16/233 (6%)
Query: 743 YRIGALVKYRCEKGYKVIG--ESLSTCEDNGQWSGTT-PTCQYVDCGNPGRIENGKVTLP 799
Y IG V Y+C+KGY I + + C+ N W + C C NG+ +P
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQ-AVP 112
Query: 800 SNATF-YGATAFYQCDENWELEGVIRRMCQENGT---WSLEPPICKEITCPDPSAQIKAG 855
+N T+ +G + C+E + L G C+ G+ WS +PPIC+++ C P +IK G
Sbjct: 113 ANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLC-TPPPKIKNG 171
Query: 856 SGLLVVTSTLSIGGEAHYQCERG-----YNLKGHQTRTCISKGQWNGTVPVCIPIDCRSP 910
Y C+ ++L G T C W+ P C + CR P
Sbjct: 172 KHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFP 231
Query: 911 GNIENGKIVISNGSTL-FGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
+ENGK + G + ++V + C + G C + W P C
Sbjct: 232 -VVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 77.8 bits (183), Expect = 2e-13
Identities = 65/256 (25%), Positives = 97/256 (37%), Gaps = 28/256 (10%)
Query: 469 DWCPDPPAVSNASVTVNG---HKAGSLASYTCENGH--ILSGSTSVTCTLGGAWSGVPP- 522
D C +PP + ++ G Y C+ G+ I +T C W V
Sbjct: 33 DACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDD 92
Query: 523 SCKYVNCGTPTIH---KGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGK---W 576
+C C P I G V NGT +G F C Y+L G E L C G W
Sbjct: 93 ACYRETC--PYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIW 150
Query: 577 SYDIPSCELTSC-PEPEVPSGGY----MEAFDYYVHSTINFHCEAG-----HKLIGEPNL 626
S P CE C P P++ +G + +E F+Y + + C+ LIGE +
Sbjct: 151 SGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYL--DAVTYSCDPAPGPDPFSLIGESTI 208
Query: 627 VCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTT-HLGSVIQYSCTTNYRLVGPVR 685
C + WS +P C+ + C + P + G G + + + + C + L G
Sbjct: 209 YCGDNSVWSRAAPECKVVKC-RFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDT 267
Query: 686 RTCTEEFQWSDSSPRC 701
C W P+C
Sbjct: 268 IVCDSNSTWDPPVPKC 283
Score = 76.2 bits (179), Expect = 6e-13
Identities = 66/252 (26%), Positives = 100/252 (39%), Gaps = 45/252 (17%)
Query: 549 GSIAQFTCEPDYWLNG--AEELVCNRDGKW-SYDIPSCELTSCP---EP----EVPSGGY 598
G + C+ Y+ A +C+R+ W +C +CP +P VP+ G
Sbjct: 57 GERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGT 116
Query: 599 MEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGE---WSGDSPTCEYIDCGKLPTLPYG 655
E F Y +H F C G+ LIGE L C+ G WSG P CE + C P + G
Sbjct: 117 YE-FGYQMH----FICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNG 171
Query: 656 --TMELLNGTTHLGSVIQYSCTTN-----YRLVGPVRRTCTEEFQWSDSSPRCEEIRCSD 708
T + +L +V YSC + L+G C + WS ++P C+ ++C
Sbjct: 172 KHTFSEVEVFEYLDAVT-YSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRF 230
Query: 709 PIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCE 768
P+V +S G + A V + C+KG+ + G C+
Sbjct: 231 PVVENGKQIS-------------------GFGKKFYYKATVMFECDKGFYLDGSDTIVCD 271
Query: 769 DNGQWSGTTPTC 780
N W P C
Sbjct: 272 SNSTWDPPVPKC 283
Score = 60.9 bits (141), Expect = 2e-08
Identities = 40/149 (26%), Positives = 59/149 (39%), Gaps = 12/149 (8%)
Query: 826 MCQENGTW-SLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGH 884
+C N TW + C TCP + + + T G + H+ C GY L G
Sbjct: 79 ICDRNHTWLPVSDDACYRETCPYIRDPLNGQA--VPANGTYEFGYQMHFICNEGYYLIGE 136
Query: 885 QTRTCISKGQ---WNGTVPVCIPIDCRSPGNIENGKIVISNGSTL-FGSSVEYYC----- 935
+ C KG W+G P+C + C P I+NGK S + +V Y C
Sbjct: 137 EILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPG 196
Query: 936 LSQYQRVGPFLRKCLDDGRWSGEEPSCEL 964
+ +G C D+ WS P C++
Sbjct: 197 PDPFSLIGESTIYCGDNSVWSRAAPECKV 225
>AL365178-1|CAH73949.1| 362|Homo sapiens CD46 molecule, complement
regulatory protein protein.
Length = 362
Score = 96.7 bits (230), Expect = 4e-19
Identities = 59/245 (24%), Positives = 101/245 (41%), Gaps = 15/245 (6%)
Query: 369 YDVGSRIVYKCPEGHMLLGDKSRH--CKKDGFWSG-APPSCKYVNCGGLTPIEDGDVALI 425
Y++G R+ YKC +G+ + + H C ++ W + +C C + +G
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA 113
Query: 426 DNRTTHGARALYSCRENFTLVGNPERTC---GDEGIWDGEAPRCLFDWCPDPPAVSNASV 482
+ G + + C E + L+G C G IW G+ P C C PP + N
Sbjct: 114 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKH 173
Query: 483 T---VNGHKAGSLASYTCE-----NGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTI 534
T V + +Y+C+ + L G +++ C WS P CK V C P +
Sbjct: 174 TFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVV 233
Query: 535 HKGSFVLINGTTTY-GSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEV 593
G + G Y + F C+ ++L+G++ +VC+ + W +P C P +
Sbjct: 234 ENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKGPRPTYKP 293
Query: 594 PSGGY 598
P Y
Sbjct: 294 PVSNY 298
Score = 90.6 bits (215), Expect = 3e-17
Identities = 53/171 (30%), Positives = 75/171 (43%), Gaps = 11/171 (6%)
Query: 742 TYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTCQYVDCGNPGRIENGKVTL 798
TY G + + C +GY +IGE + CE G WSG P C+ V C P +I+NGK T
Sbjct: 116 TYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTF 175
Query: 799 PSNATF-YGATAFYQCD-----ENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQI 852
F Y Y CD + + L G C +N WS P CK + C P +
Sbjct: 176 SEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPV--V 233
Query: 853 KAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCI 903
+ G + ++C++G+ L G T C S W+ VP C+
Sbjct: 234 ENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCL 284
Score = 84.2 bits (199), Expect = 2e-15
Identities = 60/229 (26%), Positives = 91/229 (39%), Gaps = 21/229 (9%)
Query: 432 GARALYSCRENFTLVGN--PERTCGDEGIW-DGEAPRCLFDWCP---DPPAVSNASVTVN 485
G R Y C++ + + C W C + CP DP ++ +V N
Sbjct: 57 GERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDP--LNGQAVPAN 114
Query: 486 G-HKAGSLASYTCENGHILSGSTSVTCTLGGA---WSGVPPSCKYVNCGTPT-IHKGSFV 540
G ++ G + C G+ L G + C L G+ WSG PP C+ V C P I G
Sbjct: 115 GTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHT 174
Query: 541 LINGTT-TYGSIAQFTCEP-----DYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVP 594
Y ++C+P + L G + C + WS P C++ C P V
Sbjct: 175 FSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVE 234
Query: 595 SGGYMEAFD--YYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTC 641
+G + F +Y +T+ F C+ G L G +VC + W P C
Sbjct: 235 NGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 81.0 bits (191), Expect = 2e-14
Identities = 65/258 (25%), Positives = 106/258 (41%), Gaps = 33/258 (12%)
Query: 604 YYVHSTINFHCEAGHKLIGE--PNLVCQQDGEWSGDSPTCEYID-CGKLPTLPYGTMELL 660
Y + +++ C+ G+ I + +C ++ W S Y + C + G
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA 113
Query: 661 NGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQ---WSDSSPRCEEIRCSDPIVAEKSIV 717
NGT G + + C Y L+G C + WS P CE++ C+ P +
Sbjct: 114 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNG-- 171
Query: 718 SVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKG-----YKVIGESLSTCEDNGQ 772
H + + + D V Y C+ + +IGES C DN
Sbjct: 172 -------KHTFSEVEVFEYLDA---------VTYSCDPAPGPDPFSLIGESTIYCGDNSV 215
Query: 773 WSGTTPTCQYVDCGNPGRIENGK-VTLPSNATFYGATAFYQCDENWELEGVIRRMCQENG 831
WS P C+ V C P +ENGK ++ +Y AT ++CD+ + L+G +C N
Sbjct: 216 WSRAAPECKVVKCRFPV-VENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNS 274
Query: 832 TWSLEPPICKEITCPDPS 849
TW +PP+ K + P P+
Sbjct: 275 TW--DPPVPKCLKGPRPT 290
Score = 81.0 bits (191), Expect = 2e-14
Identities = 62/233 (26%), Positives = 96/233 (41%), Gaps = 16/233 (6%)
Query: 743 YRIGALVKYRCEKGYKVIG--ESLSTCEDNGQWSGTT-PTCQYVDCGNPGRIENGKVTLP 799
Y IG V Y+C+KGY I + + C+ N W + C C NG+ +P
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQ-AVP 112
Query: 800 SNATF-YGATAFYQCDENWELEGVIRRMCQENGT---WSLEPPICKEITCPDPSAQIKAG 855
+N T+ +G + C+E + L G C+ G+ WS +PPIC+++ C P +IK G
Sbjct: 113 ANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLC-TPPPKIKNG 171
Query: 856 SGLLVVTSTLSIGGEAHYQCERG-----YNLKGHQTRTCISKGQWNGTVPVCIPIDCRSP 910
Y C+ ++L G T C W+ P C + CR P
Sbjct: 172 KHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFP 231
Query: 911 GNIENGKIVISNGSTL-FGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
+ENGK + G + ++V + C + G C + W P C
Sbjct: 232 -VVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 77.8 bits (183), Expect = 2e-13
Identities = 65/256 (25%), Positives = 97/256 (37%), Gaps = 28/256 (10%)
Query: 469 DWCPDPPAVSNASVTVNG---HKAGSLASYTCENGH--ILSGSTSVTCTLGGAWSGVPP- 522
D C +PP + ++ G Y C+ G+ I +T C W V
Sbjct: 33 DACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDD 92
Query: 523 SCKYVNCGTPTIH---KGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGK---W 576
+C C P I G V NGT +G F C Y+L G E L C G W
Sbjct: 93 ACYRETC--PYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIW 150
Query: 577 SYDIPSCELTSC-PEPEVPSGGY----MEAFDYYVHSTINFHCEAG-----HKLIGEPNL 626
S P CE C P P++ +G + +E F+Y + + C+ LIGE +
Sbjct: 151 SGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYL--DAVTYSCDPAPGPDPFSLIGESTI 208
Query: 627 VCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTT-HLGSVIQYSCTTNYRLVGPVR 685
C + WS +P C+ + C + P + G G + + + + C + L G
Sbjct: 209 YCGDNSVWSRAAPECKVVKC-RFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDT 267
Query: 686 RTCTEEFQWSDSSPRC 701
C W P+C
Sbjct: 268 IVCDSNSTWDPPVPKC 283
Score = 76.2 bits (179), Expect = 6e-13
Identities = 66/252 (26%), Positives = 100/252 (39%), Gaps = 45/252 (17%)
Query: 549 GSIAQFTCEPDYWLNG--AEELVCNRDGKW-SYDIPSCELTSCP---EP----EVPSGGY 598
G + C+ Y+ A +C+R+ W +C +CP +P VP+ G
Sbjct: 57 GERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGT 116
Query: 599 MEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGE---WSGDSPTCEYIDCGKLPTLPYG 655
E F Y +H F C G+ LIGE L C+ G WSG P CE + C P + G
Sbjct: 117 YE-FGYQMH----FICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNG 171
Query: 656 --TMELLNGTTHLGSVIQYSCTTN-----YRLVGPVRRTCTEEFQWSDSSPRCEEIRCSD 708
T + +L +V YSC + L+G C + WS ++P C+ ++C
Sbjct: 172 KHTFSEVEVFEYLDAVT-YSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRF 230
Query: 709 PIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCE 768
P+V +S G + A V + C+KG+ + G C+
Sbjct: 231 PVVENGKQIS-------------------GFGKKFYYKATVMFECDKGFYLDGSDTIVCD 271
Query: 769 DNGQWSGTTPTC 780
N W P C
Sbjct: 272 SNSTWDPPVPKC 283
Score = 60.9 bits (141), Expect = 2e-08
Identities = 40/149 (26%), Positives = 59/149 (39%), Gaps = 12/149 (8%)
Query: 826 MCQENGTW-SLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGH 884
+C N TW + C TCP + + + T G + H+ C GY L G
Sbjct: 79 ICDRNHTWLPVSDDACYRETCPYIRDPLNGQA--VPANGTYEFGYQMHFICNEGYYLIGE 136
Query: 885 QTRTCISKGQ---WNGTVPVCIPIDCRSPGNIENGKIVISNGSTL-FGSSVEYYC----- 935
+ C KG W+G P+C + C P I+NGK S + +V Y C
Sbjct: 137 EILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPG 196
Query: 936 LSQYQRVGPFLRKCLDDGRWSGEEPSCEL 964
+ +G C D+ WS P C++
Sbjct: 197 PDPFSLIGESTIYCGDNSVWSRAAPECKV 225
>AL035209-9|CAI18811.1| 349|Homo sapiens CD46 molecule, complement
regulatory protein protein.
Length = 349
Score = 96.7 bits (230), Expect = 4e-19
Identities = 59/245 (24%), Positives = 101/245 (41%), Gaps = 15/245 (6%)
Query: 369 YDVGSRIVYKCPEGHMLLGDKSRH--CKKDGFWSG-APPSCKYVNCGGLTPIEDGDVALI 425
Y++G R+ YKC +G+ + + H C ++ W + +C C + +G
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA 113
Query: 426 DNRTTHGARALYSCRENFTLVGNPERTC---GDEGIWDGEAPRCLFDWCPDPPAVSNASV 482
+ G + + C E + L+G C G IW G+ P C C PP + N
Sbjct: 114 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKH 173
Query: 483 T---VNGHKAGSLASYTCE-----NGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTI 534
T V + +Y+C+ + L G +++ C WS P CK V C P +
Sbjct: 174 TFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVV 233
Query: 535 HKGSFVLINGTTTY-GSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEV 593
G + G Y + F C+ ++L+G++ +VC+ + W +P C P +
Sbjct: 234 ENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKGPRPTYKP 293
Query: 594 PSGGY 598
P Y
Sbjct: 294 PVSNY 298
Score = 90.6 bits (215), Expect = 3e-17
Identities = 53/171 (30%), Positives = 75/171 (43%), Gaps = 11/171 (6%)
Query: 742 TYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTCQYVDCGNPGRIENGKVTL 798
TY G + + C +GY +IGE + CE G WSG P C+ V C P +I+NGK T
Sbjct: 116 TYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTF 175
Query: 799 PSNATF-YGATAFYQCD-----ENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQI 852
F Y Y CD + + L G C +N WS P CK + C P +
Sbjct: 176 SEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPV--V 233
Query: 853 KAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCI 903
+ G + ++C++G+ L G T C S W+ VP C+
Sbjct: 234 ENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCL 284
Score = 84.2 bits (199), Expect = 2e-15
Identities = 60/229 (26%), Positives = 91/229 (39%), Gaps = 21/229 (9%)
Query: 432 GARALYSCRENFTLVGN--PERTCGDEGIW-DGEAPRCLFDWCP---DPPAVSNASVTVN 485
G R Y C++ + + C W C + CP DP ++ +V N
Sbjct: 57 GERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDP--LNGQAVPAN 114
Query: 486 G-HKAGSLASYTCENGHILSGSTSVTCTLGGA---WSGVPPSCKYVNCGTPT-IHKGSFV 540
G ++ G + C G+ L G + C L G+ WSG PP C+ V C P I G
Sbjct: 115 GTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHT 174
Query: 541 LINGTT-TYGSIAQFTCEP-----DYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVP 594
Y ++C+P + L G + C + WS P C++ C P V
Sbjct: 175 FSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVE 234
Query: 595 SGGYMEAFD--YYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTC 641
+G + F +Y +T+ F C+ G L G +VC + W P C
Sbjct: 235 NGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 81.0 bits (191), Expect = 2e-14
Identities = 65/258 (25%), Positives = 106/258 (41%), Gaps = 33/258 (12%)
Query: 604 YYVHSTINFHCEAGHKLIGE--PNLVCQQDGEWSGDSPTCEYID-CGKLPTLPYGTMELL 660
Y + +++ C+ G+ I + +C ++ W S Y + C + G
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA 113
Query: 661 NGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQ---WSDSSPRCEEIRCSDPIVAEKSIV 717
NGT G + + C Y L+G C + WS P CE++ C+ P +
Sbjct: 114 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNG-- 171
Query: 718 SVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKG-----YKVIGESLSTCEDNGQ 772
H + + + D V Y C+ + +IGES C DN
Sbjct: 172 -------KHTFSEVEVFEYLDA---------VTYSCDPAPGPDPFSLIGESTIYCGDNSV 215
Query: 773 WSGTTPTCQYVDCGNPGRIENGK-VTLPSNATFYGATAFYQCDENWELEGVIRRMCQENG 831
WS P C+ V C P +ENGK ++ +Y AT ++CD+ + L+G +C N
Sbjct: 216 WSRAAPECKVVKCRFPV-VENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNS 274
Query: 832 TWSLEPPICKEITCPDPS 849
TW +PP+ K + P P+
Sbjct: 275 TW--DPPVPKCLKGPRPT 290
Score = 81.0 bits (191), Expect = 2e-14
Identities = 62/233 (26%), Positives = 96/233 (41%), Gaps = 16/233 (6%)
Query: 743 YRIGALVKYRCEKGYKVIG--ESLSTCEDNGQWSGTT-PTCQYVDCGNPGRIENGKVTLP 799
Y IG V Y+C+KGY I + + C+ N W + C C NG+ +P
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQ-AVP 112
Query: 800 SNATF-YGATAFYQCDENWELEGVIRRMCQENGT---WSLEPPICKEITCPDPSAQIKAG 855
+N T+ +G + C+E + L G C+ G+ WS +PPIC+++ C P +IK G
Sbjct: 113 ANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLC-TPPPKIKNG 171
Query: 856 SGLLVVTSTLSIGGEAHYQCERG-----YNLKGHQTRTCISKGQWNGTVPVCIPIDCRSP 910
Y C+ ++L G T C W+ P C + CR P
Sbjct: 172 KHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFP 231
Query: 911 GNIENGKIVISNGSTL-FGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
+ENGK + G + ++V + C + G C + W P C
Sbjct: 232 -VVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 77.8 bits (183), Expect = 2e-13
Identities = 65/256 (25%), Positives = 97/256 (37%), Gaps = 28/256 (10%)
Query: 469 DWCPDPPAVSNASVTVNG---HKAGSLASYTCENGH--ILSGSTSVTCTLGGAWSGVPP- 522
D C +PP + ++ G Y C+ G+ I +T C W V
Sbjct: 33 DACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDD 92
Query: 523 SCKYVNCGTPTIH---KGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGK---W 576
+C C P I G V NGT +G F C Y+L G E L C G W
Sbjct: 93 ACYRETC--PYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIW 150
Query: 577 SYDIPSCELTSC-PEPEVPSGGY----MEAFDYYVHSTINFHCEAG-----HKLIGEPNL 626
S P CE C P P++ +G + +E F+Y + + C+ LIGE +
Sbjct: 151 SGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYL--DAVTYSCDPAPGPDPFSLIGESTI 208
Query: 627 VCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTT-HLGSVIQYSCTTNYRLVGPVR 685
C + WS +P C+ + C + P + G G + + + + C + L G
Sbjct: 209 YCGDNSVWSRAAPECKVVKC-RFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDT 267
Query: 686 RTCTEEFQWSDSSPRC 701
C W P+C
Sbjct: 268 IVCDSNSTWDPPVPKC 283
Score = 76.2 bits (179), Expect = 6e-13
Identities = 66/252 (26%), Positives = 100/252 (39%), Gaps = 45/252 (17%)
Query: 549 GSIAQFTCEPDYWLNG--AEELVCNRDGKW-SYDIPSCELTSCP---EP----EVPSGGY 598
G + C+ Y+ A +C+R+ W +C +CP +P VP+ G
Sbjct: 57 GERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGT 116
Query: 599 MEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGE---WSGDSPTCEYIDCGKLPTLPYG 655
E F Y +H F C G+ LIGE L C+ G WSG P CE + C P + G
Sbjct: 117 YE-FGYQMH----FICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNG 171
Query: 656 --TMELLNGTTHLGSVIQYSCTTN-----YRLVGPVRRTCTEEFQWSDSSPRCEEIRCSD 708
T + +L +V YSC + L+G C + WS ++P C+ ++C
Sbjct: 172 KHTFSEVEVFEYLDAVT-YSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRF 230
Query: 709 PIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCE 768
P+V +S G + A V + C+KG+ + G C+
Sbjct: 231 PVVENGKQIS-------------------GFGKKFYYKATVMFECDKGFYLDGSDTIVCD 271
Query: 769 DNGQWSGTTPTC 780
N W P C
Sbjct: 272 SNSTWDPPVPKC 283
Score = 60.9 bits (141), Expect = 2e-08
Identities = 40/149 (26%), Positives = 59/149 (39%), Gaps = 12/149 (8%)
Query: 826 MCQENGTW-SLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGH 884
+C N TW + C TCP + + + T G + H+ C GY L G
Sbjct: 79 ICDRNHTWLPVSDDACYRETCPYIRDPLNGQA--VPANGTYEFGYQMHFICNEGYYLIGE 136
Query: 885 QTRTCISKGQ---WNGTVPVCIPIDCRSPGNIENGKIVISNGSTL-FGSSVEYYC----- 935
+ C KG W+G P+C + C P I+NGK S + +V Y C
Sbjct: 137 EILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPG 196
Query: 936 LSQYQRVGPFLRKCLDDGRWSGEEPSCEL 964
+ +G C D+ WS P C++
Sbjct: 197 PDPFSLIGESTIYCGDNSVWSRAAPECKV 225
>AL035209-7|CAI18808.1| 369|Homo sapiens CD46 molecule, complement
regulatory protein protein.
Length = 369
Score = 96.7 bits (230), Expect = 4e-19
Identities = 59/245 (24%), Positives = 101/245 (41%), Gaps = 15/245 (6%)
Query: 369 YDVGSRIVYKCPEGHMLLGDKSRH--CKKDGFWSG-APPSCKYVNCGGLTPIEDGDVALI 425
Y++G R+ YKC +G+ + + H C ++ W + +C C + +G
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA 113
Query: 426 DNRTTHGARALYSCRENFTLVGNPERTC---GDEGIWDGEAPRCLFDWCPDPPAVSNASV 482
+ G + + C E + L+G C G IW G+ P C C PP + N
Sbjct: 114 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKH 173
Query: 483 T---VNGHKAGSLASYTCE-----NGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTI 534
T V + +Y+C+ + L G +++ C WS P CK V C P +
Sbjct: 174 TFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVV 233
Query: 535 HKGSFVLINGTTTY-GSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEV 593
G + G Y + F C+ ++L+G++ +VC+ + W +P C P +
Sbjct: 234 ENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKGPRPTYKP 293
Query: 594 PSGGY 598
P Y
Sbjct: 294 PVSNY 298
Score = 90.6 bits (215), Expect = 3e-17
Identities = 53/171 (30%), Positives = 75/171 (43%), Gaps = 11/171 (6%)
Query: 742 TYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTCQYVDCGNPGRIENGKVTL 798
TY G + + C +GY +IGE + CE G WSG P C+ V C P +I+NGK T
Sbjct: 116 TYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTF 175
Query: 799 PSNATF-YGATAFYQCD-----ENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQI 852
F Y Y CD + + L G C +N WS P CK + C P +
Sbjct: 176 SEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPV--V 233
Query: 853 KAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCI 903
+ G + ++C++G+ L G T C S W+ VP C+
Sbjct: 234 ENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCL 284
Score = 84.2 bits (199), Expect = 2e-15
Identities = 60/229 (26%), Positives = 91/229 (39%), Gaps = 21/229 (9%)
Query: 432 GARALYSCRENFTLVGN--PERTCGDEGIW-DGEAPRCLFDWCP---DPPAVSNASVTVN 485
G R Y C++ + + C W C + CP DP ++ +V N
Sbjct: 57 GERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDP--LNGQAVPAN 114
Query: 486 G-HKAGSLASYTCENGHILSGSTSVTCTLGGA---WSGVPPSCKYVNCGTPT-IHKGSFV 540
G ++ G + C G+ L G + C L G+ WSG PP C+ V C P I G
Sbjct: 115 GTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHT 174
Query: 541 LINGTT-TYGSIAQFTCEP-----DYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVP 594
Y ++C+P + L G + C + WS P C++ C P V
Sbjct: 175 FSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVE 234
Query: 595 SGGYMEAFD--YYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTC 641
+G + F +Y +T+ F C+ G L G +VC + W P C
Sbjct: 235 NGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 81.0 bits (191), Expect = 2e-14
Identities = 65/258 (25%), Positives = 106/258 (41%), Gaps = 33/258 (12%)
Query: 604 YYVHSTINFHCEAGHKLIGE--PNLVCQQDGEWSGDSPTCEYID-CGKLPTLPYGTMELL 660
Y + +++ C+ G+ I + +C ++ W S Y + C + G
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA 113
Query: 661 NGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQ---WSDSSPRCEEIRCSDPIVAEKSIV 717
NGT G + + C Y L+G C + WS P CE++ C+ P +
Sbjct: 114 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNG-- 171
Query: 718 SVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKG-----YKVIGESLSTCEDNGQ 772
H + + + D V Y C+ + +IGES C DN
Sbjct: 172 -------KHTFSEVEVFEYLDA---------VTYSCDPAPGPDPFSLIGESTIYCGDNSV 215
Query: 773 WSGTTPTCQYVDCGNPGRIENGK-VTLPSNATFYGATAFYQCDENWELEGVIRRMCQENG 831
WS P C+ V C P +ENGK ++ +Y AT ++CD+ + L+G +C N
Sbjct: 216 WSRAAPECKVVKCRFPV-VENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNS 274
Query: 832 TWSLEPPICKEITCPDPS 849
TW +PP+ K + P P+
Sbjct: 275 TW--DPPVPKCLKGPRPT 290
Score = 81.0 bits (191), Expect = 2e-14
Identities = 62/233 (26%), Positives = 96/233 (41%), Gaps = 16/233 (6%)
Query: 743 YRIGALVKYRCEKGYKVIG--ESLSTCEDNGQWSGTT-PTCQYVDCGNPGRIENGKVTLP 799
Y IG V Y+C+KGY I + + C+ N W + C C NG+ +P
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQ-AVP 112
Query: 800 SNATF-YGATAFYQCDENWELEGVIRRMCQENGT---WSLEPPICKEITCPDPSAQIKAG 855
+N T+ +G + C+E + L G C+ G+ WS +PPIC+++ C P +IK G
Sbjct: 113 ANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLC-TPPPKIKNG 171
Query: 856 SGLLVVTSTLSIGGEAHYQCERG-----YNLKGHQTRTCISKGQWNGTVPVCIPIDCRSP 910
Y C+ ++L G T C W+ P C + CR P
Sbjct: 172 KHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFP 231
Query: 911 GNIENGKIVISNGSTL-FGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
+ENGK + G + ++V + C + G C + W P C
Sbjct: 232 -VVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 77.8 bits (183), Expect = 2e-13
Identities = 65/256 (25%), Positives = 97/256 (37%), Gaps = 28/256 (10%)
Query: 469 DWCPDPPAVSNASVTVNG---HKAGSLASYTCENGH--ILSGSTSVTCTLGGAWSGVPP- 522
D C +PP + ++ G Y C+ G+ I +T C W V
Sbjct: 33 DACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDD 92
Query: 523 SCKYVNCGTPTIH---KGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGK---W 576
+C C P I G V NGT +G F C Y+L G E L C G W
Sbjct: 93 ACYRETC--PYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIW 150
Query: 577 SYDIPSCELTSC-PEPEVPSGGY----MEAFDYYVHSTINFHCEAG-----HKLIGEPNL 626
S P CE C P P++ +G + +E F+Y + + C+ LIGE +
Sbjct: 151 SGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYL--DAVTYSCDPAPGPDPFSLIGESTI 208
Query: 627 VCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTT-HLGSVIQYSCTTNYRLVGPVR 685
C + WS +P C+ + C + P + G G + + + + C + L G
Sbjct: 209 YCGDNSVWSRAAPECKVVKC-RFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDT 267
Query: 686 RTCTEEFQWSDSSPRC 701
C W P+C
Sbjct: 268 IVCDSNSTWDPPVPKC 283
Score = 76.2 bits (179), Expect = 6e-13
Identities = 66/252 (26%), Positives = 100/252 (39%), Gaps = 45/252 (17%)
Query: 549 GSIAQFTCEPDYWLNG--AEELVCNRDGKW-SYDIPSCELTSCP---EP----EVPSGGY 598
G + C+ Y+ A +C+R+ W +C +CP +P VP+ G
Sbjct: 57 GERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGT 116
Query: 599 MEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGE---WSGDSPTCEYIDCGKLPTLPYG 655
E F Y +H F C G+ LIGE L C+ G WSG P CE + C P + G
Sbjct: 117 YE-FGYQMH----FICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNG 171
Query: 656 --TMELLNGTTHLGSVIQYSCTTN-----YRLVGPVRRTCTEEFQWSDSSPRCEEIRCSD 708
T + +L +V YSC + L+G C + WS ++P C+ ++C
Sbjct: 172 KHTFSEVEVFEYLDAVT-YSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRF 230
Query: 709 PIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCE 768
P+V +S G + A V + C+KG+ + G C+
Sbjct: 231 PVVENGKQIS-------------------GFGKKFYYKATVMFECDKGFYLDGSDTIVCD 271
Query: 769 DNGQWSGTTPTC 780
N W P C
Sbjct: 272 SNSTWDPPVPKC 283
Score = 60.9 bits (141), Expect = 2e-08
Identities = 40/149 (26%), Positives = 59/149 (39%), Gaps = 12/149 (8%)
Query: 826 MCQENGTW-SLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGH 884
+C N TW + C TCP + + + T G + H+ C GY L G
Sbjct: 79 ICDRNHTWLPVSDDACYRETCPYIRDPLNGQA--VPANGTYEFGYQMHFICNEGYYLIGE 136
Query: 885 QTRTCISKGQ---WNGTVPVCIPIDCRSPGNIENGKIVISNGSTL-FGSSVEYYC----- 935
+ C KG W+G P+C + C P I+NGK S + +V Y C
Sbjct: 137 EILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPG 196
Query: 936 LSQYQRVGPFLRKCLDDGRWSGEEPSCEL 964
+ +G C D+ WS P C++
Sbjct: 197 PDPFSLIGESTIYCGDNSVWSRAAPECKV 225
>AL035209-2|CAI18804.1| 362|Homo sapiens CD46 molecule, complement
regulatory protein protein.
Length = 362
Score = 96.7 bits (230), Expect = 4e-19
Identities = 59/245 (24%), Positives = 101/245 (41%), Gaps = 15/245 (6%)
Query: 369 YDVGSRIVYKCPEGHMLLGDKSRH--CKKDGFWSG-APPSCKYVNCGGLTPIEDGDVALI 425
Y++G R+ YKC +G+ + + H C ++ W + +C C + +G
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA 113
Query: 426 DNRTTHGARALYSCRENFTLVGNPERTC---GDEGIWDGEAPRCLFDWCPDPPAVSNASV 482
+ G + + C E + L+G C G IW G+ P C C PP + N
Sbjct: 114 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKH 173
Query: 483 T---VNGHKAGSLASYTCE-----NGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTI 534
T V + +Y+C+ + L G +++ C WS P CK V C P +
Sbjct: 174 TFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVV 233
Query: 535 HKGSFVLINGTTTY-GSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEV 593
G + G Y + F C+ ++L+G++ +VC+ + W +P C P +
Sbjct: 234 ENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKGPRPTYKP 293
Query: 594 PSGGY 598
P Y
Sbjct: 294 PVSNY 298
Score = 90.6 bits (215), Expect = 3e-17
Identities = 53/171 (30%), Positives = 75/171 (43%), Gaps = 11/171 (6%)
Query: 742 TYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTCQYVDCGNPGRIENGKVTL 798
TY G + + C +GY +IGE + CE G WSG P C+ V C P +I+NGK T
Sbjct: 116 TYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTF 175
Query: 799 PSNATF-YGATAFYQCD-----ENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQI 852
F Y Y CD + + L G C +N WS P CK + C P +
Sbjct: 176 SEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPV--V 233
Query: 853 KAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCI 903
+ G + ++C++G+ L G T C S W+ VP C+
Sbjct: 234 ENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCL 284
Score = 84.2 bits (199), Expect = 2e-15
Identities = 60/229 (26%), Positives = 91/229 (39%), Gaps = 21/229 (9%)
Query: 432 GARALYSCRENFTLVGN--PERTCGDEGIW-DGEAPRCLFDWCP---DPPAVSNASVTVN 485
G R Y C++ + + C W C + CP DP ++ +V N
Sbjct: 57 GERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDP--LNGQAVPAN 114
Query: 486 G-HKAGSLASYTCENGHILSGSTSVTCTLGGA---WSGVPPSCKYVNCGTPT-IHKGSFV 540
G ++ G + C G+ L G + C L G+ WSG PP C+ V C P I G
Sbjct: 115 GTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHT 174
Query: 541 LINGTT-TYGSIAQFTCEP-----DYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVP 594
Y ++C+P + L G + C + WS P C++ C P V
Sbjct: 175 FSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVE 234
Query: 595 SGGYMEAFD--YYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTC 641
+G + F +Y +T+ F C+ G L G +VC + W P C
Sbjct: 235 NGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 81.0 bits (191), Expect = 2e-14
Identities = 65/258 (25%), Positives = 106/258 (41%), Gaps = 33/258 (12%)
Query: 604 YYVHSTINFHCEAGHKLIGE--PNLVCQQDGEWSGDSPTCEYID-CGKLPTLPYGTMELL 660
Y + +++ C+ G+ I + +C ++ W S Y + C + G
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA 113
Query: 661 NGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQ---WSDSSPRCEEIRCSDPIVAEKSIV 717
NGT G + + C Y L+G C + WS P CE++ C+ P +
Sbjct: 114 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNG-- 171
Query: 718 SVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKG-----YKVIGESLSTCEDNGQ 772
H + + + D V Y C+ + +IGES C DN
Sbjct: 172 -------KHTFSEVEVFEYLDA---------VTYSCDPAPGPDPFSLIGESTIYCGDNSV 215
Query: 773 WSGTTPTCQYVDCGNPGRIENGK-VTLPSNATFYGATAFYQCDENWELEGVIRRMCQENG 831
WS P C+ V C P +ENGK ++ +Y AT ++CD+ + L+G +C N
Sbjct: 216 WSRAAPECKVVKCRFPV-VENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNS 274
Query: 832 TWSLEPPICKEITCPDPS 849
TW +PP+ K + P P+
Sbjct: 275 TW--DPPVPKCLKGPRPT 290
Score = 81.0 bits (191), Expect = 2e-14
Identities = 62/233 (26%), Positives = 96/233 (41%), Gaps = 16/233 (6%)
Query: 743 YRIGALVKYRCEKGYKVIG--ESLSTCEDNGQWSGTT-PTCQYVDCGNPGRIENGKVTLP 799
Y IG V Y+C+KGY I + + C+ N W + C C NG+ +P
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQ-AVP 112
Query: 800 SNATF-YGATAFYQCDENWELEGVIRRMCQENGT---WSLEPPICKEITCPDPSAQIKAG 855
+N T+ +G + C+E + L G C+ G+ WS +PPIC+++ C P +IK G
Sbjct: 113 ANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLC-TPPPKIKNG 171
Query: 856 SGLLVVTSTLSIGGEAHYQCERG-----YNLKGHQTRTCISKGQWNGTVPVCIPIDCRSP 910
Y C+ ++L G T C W+ P C + CR P
Sbjct: 172 KHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFP 231
Query: 911 GNIENGKIVISNGSTL-FGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
+ENGK + G + ++V + C + G C + W P C
Sbjct: 232 -VVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 77.8 bits (183), Expect = 2e-13
Identities = 65/256 (25%), Positives = 97/256 (37%), Gaps = 28/256 (10%)
Query: 469 DWCPDPPAVSNASVTVNG---HKAGSLASYTCENGH--ILSGSTSVTCTLGGAWSGVPP- 522
D C +PP + ++ G Y C+ G+ I +T C W V
Sbjct: 33 DACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDD 92
Query: 523 SCKYVNCGTPTIH---KGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGK---W 576
+C C P I G V NGT +G F C Y+L G E L C G W
Sbjct: 93 ACYRETC--PYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIW 150
Query: 577 SYDIPSCELTSC-PEPEVPSGGY----MEAFDYYVHSTINFHCEAG-----HKLIGEPNL 626
S P CE C P P++ +G + +E F+Y + + C+ LIGE +
Sbjct: 151 SGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYL--DAVTYSCDPAPGPDPFSLIGESTI 208
Query: 627 VCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTT-HLGSVIQYSCTTNYRLVGPVR 685
C + WS +P C+ + C + P + G G + + + + C + L G
Sbjct: 209 YCGDNSVWSRAAPECKVVKC-RFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDT 267
Query: 686 RTCTEEFQWSDSSPRC 701
C W P+C
Sbjct: 268 IVCDSNSTWDPPVPKC 283
Score = 76.2 bits (179), Expect = 6e-13
Identities = 66/252 (26%), Positives = 100/252 (39%), Gaps = 45/252 (17%)
Query: 549 GSIAQFTCEPDYWLNG--AEELVCNRDGKW-SYDIPSCELTSCP---EP----EVPSGGY 598
G + C+ Y+ A +C+R+ W +C +CP +P VP+ G
Sbjct: 57 GERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGT 116
Query: 599 MEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGE---WSGDSPTCEYIDCGKLPTLPYG 655
E F Y +H F C G+ LIGE L C+ G WSG P CE + C P + G
Sbjct: 117 YE-FGYQMH----FICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNG 171
Query: 656 --TMELLNGTTHLGSVIQYSCTTN-----YRLVGPVRRTCTEEFQWSDSSPRCEEIRCSD 708
T + +L +V YSC + L+G C + WS ++P C+ ++C
Sbjct: 172 KHTFSEVEVFEYLDAVT-YSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRF 230
Query: 709 PIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCE 768
P+V +S G + A V + C+KG+ + G C+
Sbjct: 231 PVVENGKQIS-------------------GFGKKFYYKATVMFECDKGFYLDGSDTIVCD 271
Query: 769 DNGQWSGTTPTC 780
N W P C
Sbjct: 272 SNSTWDPPVPKC 283
Score = 60.9 bits (141), Expect = 2e-08
Identities = 40/149 (26%), Positives = 59/149 (39%), Gaps = 12/149 (8%)
Query: 826 MCQENGTW-SLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGH 884
+C N TW + C TCP + + + T G + H+ C GY L G
Sbjct: 79 ICDRNHTWLPVSDDACYRETCPYIRDPLNGQA--VPANGTYEFGYQMHFICNEGYYLIGE 136
Query: 885 QTRTCISKGQ---WNGTVPVCIPIDCRSPGNIENGKIVISNGSTL-FGSSVEYYC----- 935
+ C KG W+G P+C + C P I+NGK S + +V Y C
Sbjct: 137 EILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPG 196
Query: 936 LSQYQRVGPFLRKCLDDGRWSGEEPSCEL 964
+ +G C D+ WS P C++
Sbjct: 197 PDPFSLIGESTIYCGDNSVWSRAAPECKV 225
>Y00651-1|CAA68675.1| 384|Homo sapiens protein ( Human mRNA for
membrane cofactor protein. ).
Length = 384
Score = 95.5 bits (227), Expect = 9e-19
Identities = 56/230 (24%), Positives = 97/230 (42%), Gaps = 15/230 (6%)
Query: 369 YDVGSRIVYKCPEGHMLLGDKSRH--CKKDGFWSG-APPSCKYVNCGGLTPIEDGDVALI 425
Y++G R+ YKC +G+ + + H C ++ W + +C C + +G
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA 113
Query: 426 DNRTTHGARALYSCRENFTLVGNPERTC---GDEGIWDGEAPRCLFDWCPDPPAVSNASV 482
+ G + + C E + L+G C G IW G+ P C C PP + N
Sbjct: 114 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKH 173
Query: 483 T---VNGHKAGSLASYTCE-----NGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTI 534
T V + +Y+C+ + L G +++ C WS P CK V C P +
Sbjct: 174 TFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVV 233
Query: 535 HKGSFVLINGTTTY-GSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSC 583
G + G Y + F C+ ++L+G++ +VC+ + W +P C
Sbjct: 234 ENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 92.3 bits (219), Expect = 9e-18
Identities = 54/177 (30%), Positives = 77/177 (43%), Gaps = 11/177 (6%)
Query: 742 TYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTCQYVDCGNPGRIENGKVTL 798
TY G + + C +GY +IGE + CE G WSG P C+ V C P +I+NGK T
Sbjct: 116 TYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTF 175
Query: 799 PSNATF-YGATAFYQCD-----ENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQI 852
F Y Y CD + + L G C +N WS P CK + C P +
Sbjct: 176 SEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPV--V 233
Query: 853 KAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRS 909
+ G + ++C++G+ L G T C S W+ VP C+ + S
Sbjct: 234 ENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVSTSS 290
Score = 84.2 bits (199), Expect = 2e-15
Identities = 60/229 (26%), Positives = 91/229 (39%), Gaps = 21/229 (9%)
Query: 432 GARALYSCRENFTLVGN--PERTCGDEGIW-DGEAPRCLFDWCP---DPPAVSNASVTVN 485
G R Y C++ + + C W C + CP DP ++ +V N
Sbjct: 57 GERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDP--LNGQAVPAN 114
Query: 486 G-HKAGSLASYTCENGHILSGSTSVTCTLGGA---WSGVPPSCKYVNCGTPT-IHKGSFV 540
G ++ G + C G+ L G + C L G+ WSG PP C+ V C P I G
Sbjct: 115 GTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHT 174
Query: 541 LINGTT-TYGSIAQFTCEP-----DYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVP 594
Y ++C+P + L G + C + WS P C++ C P V
Sbjct: 175 FSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVE 234
Query: 595 SGGYMEAFD--YYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTC 641
+G + F +Y +T+ F C+ G L G +VC + W P C
Sbjct: 235 NGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 81.4 bits (192), Expect = 2e-14
Identities = 64/244 (26%), Positives = 102/244 (41%), Gaps = 17/244 (6%)
Query: 743 YRIGALVKYRCEKGYKVIG--ESLSTCEDNGQWSGTT-PTCQYVDCGNPGRIENGKVTLP 799
Y IG V Y+C+KGY I + + C+ N W + C C NG+ +P
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQ-AVP 112
Query: 800 SNATF-YGATAFYQCDENWELEGVIRRMCQENGT---WSLEPPICKEITCPDPSAQIKAG 855
+N T+ +G + C+E + L G C+ G+ WS +PPIC+++ C P +IK G
Sbjct: 113 ANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLC-TPPPKIKNG 171
Query: 856 SGLLVVTSTLSIGGEAHYQCERG-----YNLKGHQTRTCISKGQWNGTVPVCIPIDCRSP 910
Y C+ ++L G T C W+ P C + CR P
Sbjct: 172 KHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFP 231
Query: 911 GNIENGKIVISNGSTL-FGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC-ELATNE 968
+ENGK + G + ++V + C + G C + W P C +++T+
Sbjct: 232 -VVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVSTSS 290
Query: 969 AVDS 972
S
Sbjct: 291 TTKS 294
Score = 81.4 bits (192), Expect = 2e-14
Identities = 49/176 (27%), Positives = 78/176 (44%), Gaps = 11/176 (6%)
Query: 369 YDVGSRIVYKCPEGHMLLGDKSRHCKKDG---FWSGAPPSCKYVNCGGLTPIEDGDVALI 425
Y+ G ++ + C EG+ L+G++ +C+ G WSG PP C+ V C I++G
Sbjct: 117 YEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFS 176
Query: 426 DNRTTHGARAL-YSCR-----ENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSN 479
+ A+ YSC + F+L+G CGD +W AP C C P +
Sbjct: 177 EVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVENG 236
Query: 480 ASVTVNGHKAGSLAS--YTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPT 533
++ G K A+ + C+ G L GS ++ C W P C V+ + T
Sbjct: 237 KQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVSTSSTT 292
Score = 79.4 bits (187), Expect = 6e-14
Identities = 68/273 (24%), Positives = 103/273 (37%), Gaps = 28/273 (10%)
Query: 469 DWCPDPPAVSNASVTVNG---HKAGSLASYTCENGH--ILSGSTSVTCTLGGAWSGVPP- 522
D C +PP + ++ G Y C+ G+ I +T C W V
Sbjct: 33 DACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDD 92
Query: 523 SCKYVNCGTPTIH---KGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGK---W 576
+C C P I G V NGT +G F C Y+L G E L C G W
Sbjct: 93 ACYRETC--PYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIW 150
Query: 577 SYDIPSCELTSC-PEPEVPSGGY----MEAFDYYVHSTINFHCEAG-----HKLIGEPNL 626
S P CE C P P++ +G + +E F+Y + + C+ LIGE +
Sbjct: 151 SGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYL--DAVTYSCDPAPGPDPFSLIGESTI 208
Query: 627 VCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTT-HLGSVIQYSCTTNYRLVGPVR 685
C + WS +P C+ + C + P + G G + + + + C + L G
Sbjct: 209 YCGDNSVWSRAAPECKVVKC-RFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDT 267
Query: 686 RTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVS 718
C W P+C ++ S + S S
Sbjct: 268 IVCDSNSTWDPPVPKCLKVSTSSTTKSPASSAS 300
Score = 76.2 bits (179), Expect = 6e-13
Identities = 66/252 (26%), Positives = 100/252 (39%), Gaps = 45/252 (17%)
Query: 549 GSIAQFTCEPDYWLNG--AEELVCNRDGKW-SYDIPSCELTSCP---EP----EVPSGGY 598
G + C+ Y+ A +C+R+ W +C +CP +P VP+ G
Sbjct: 57 GERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGT 116
Query: 599 MEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGE---WSGDSPTCEYIDCGKLPTLPYG 655
E F Y +H F C G+ LIGE L C+ G WSG P CE + C P + G
Sbjct: 117 YE-FGYQMH----FICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNG 171
Query: 656 --TMELLNGTTHLGSVIQYSCTTN-----YRLVGPVRRTCTEEFQWSDSSPRCEEIRCSD 708
T + +L +V YSC + L+G C + WS ++P C+ ++C
Sbjct: 172 KHTFSEVEVFEYLDAVT-YSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRF 230
Query: 709 PIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCE 768
P+V +S G + A V + C+KG+ + G C+
Sbjct: 231 PVVENGKQIS-------------------GFGKKFYYKATVMFECDKGFYLDGSDTIVCD 271
Query: 769 DNGQWSGTTPTC 780
N W P C
Sbjct: 272 SNSTWDPPVPKC 283
Score = 55.2 bits (127), Expect = 1e-06
Identities = 32/124 (25%), Positives = 54/124 (43%), Gaps = 10/124 (8%)
Query: 353 CGSPDKLLNTTILGNDYDVGS---RIVYKC-----PEGHMLLGDKSRHCKKDGFWSGAPP 404
C P K+ N ++ +V + Y C P+ L+G+ + +C + WS A P
Sbjct: 162 CTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAP 221
Query: 405 SCKYVNCGGLTPIEDG-DVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEA 463
CK V C +E+G ++ + + A ++ C + F L G+ C WD
Sbjct: 222 ECKVVKCR-FPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPV 280
Query: 464 PRCL 467
P+CL
Sbjct: 281 PKCL 284
>M58050-1|AAA62833.1| 377|Homo sapiens membrane cofactor protein
protein.
Length = 377
Score = 95.5 bits (227), Expect = 9e-19
Identities = 56/230 (24%), Positives = 97/230 (42%), Gaps = 15/230 (6%)
Query: 369 YDVGSRIVYKCPEGHMLLGDKSRH--CKKDGFWSG-APPSCKYVNCGGLTPIEDGDVALI 425
Y++G R+ YKC +G+ + + H C ++ W + +C C + +G
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA 113
Query: 426 DNRTTHGARALYSCRENFTLVGNPERTC---GDEGIWDGEAPRCLFDWCPDPPAVSNASV 482
+ G + + C E + L+G C G IW G+ P C C PP + N
Sbjct: 114 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKH 173
Query: 483 T---VNGHKAGSLASYTCE-----NGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTI 534
T V + +Y+C+ + L G +++ C WS P CK V C P +
Sbjct: 174 TFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVV 233
Query: 535 HKGSFVLINGTTTY-GSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSC 583
G + G Y + F C+ ++L+G++ +VC+ + W +P C
Sbjct: 234 ENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 92.3 bits (219), Expect = 9e-18
Identities = 54/177 (30%), Positives = 77/177 (43%), Gaps = 11/177 (6%)
Query: 742 TYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTCQYVDCGNPGRIENGKVTL 798
TY G + + C +GY +IGE + CE G WSG P C+ V C P +I+NGK T
Sbjct: 116 TYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTF 175
Query: 799 PSNATF-YGATAFYQCD-----ENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQI 852
F Y Y CD + + L G C +N WS P CK + C P +
Sbjct: 176 SEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPV--V 233
Query: 853 KAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRS 909
+ G + ++C++G+ L G T C S W+ VP C+ + S
Sbjct: 234 ENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVSTSS 290
Score = 84.2 bits (199), Expect = 2e-15
Identities = 60/229 (26%), Positives = 91/229 (39%), Gaps = 21/229 (9%)
Query: 432 GARALYSCRENFTLVGN--PERTCGDEGIW-DGEAPRCLFDWCP---DPPAVSNASVTVN 485
G R Y C++ + + C W C + CP DP ++ +V N
Sbjct: 57 GERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDP--LNGQAVPAN 114
Query: 486 G-HKAGSLASYTCENGHILSGSTSVTCTLGGA---WSGVPPSCKYVNCGTPT-IHKGSFV 540
G ++ G + C G+ L G + C L G+ WSG PP C+ V C P I G
Sbjct: 115 GTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHT 174
Query: 541 LINGTT-TYGSIAQFTCEP-----DYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVP 594
Y ++C+P + L G + C + WS P C++ C P V
Sbjct: 175 FSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVE 234
Query: 595 SGGYMEAFD--YYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTC 641
+G + F +Y +T+ F C+ G L G +VC + W P C
Sbjct: 235 NGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 81.4 bits (192), Expect = 2e-14
Identities = 64/244 (26%), Positives = 102/244 (41%), Gaps = 17/244 (6%)
Query: 743 YRIGALVKYRCEKGYKVIG--ESLSTCEDNGQWSGTT-PTCQYVDCGNPGRIENGKVTLP 799
Y IG V Y+C+KGY I + + C+ N W + C C NG+ +P
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQ-AVP 112
Query: 800 SNATF-YGATAFYQCDENWELEGVIRRMCQENGT---WSLEPPICKEITCPDPSAQIKAG 855
+N T+ +G + C+E + L G C+ G+ WS +PPIC+++ C P +IK G
Sbjct: 113 ANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLC-TPPPKIKNG 171
Query: 856 SGLLVVTSTLSIGGEAHYQCERG-----YNLKGHQTRTCISKGQWNGTVPVCIPIDCRSP 910
Y C+ ++L G T C W+ P C + CR P
Sbjct: 172 KHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFP 231
Query: 911 GNIENGKIVISNGSTL-FGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC-ELATNE 968
+ENGK + G + ++V + C + G C + W P C +++T+
Sbjct: 232 -VVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVSTSS 290
Query: 969 AVDS 972
S
Sbjct: 291 TTKS 294
Score = 81.4 bits (192), Expect = 2e-14
Identities = 49/176 (27%), Positives = 78/176 (44%), Gaps = 11/176 (6%)
Query: 369 YDVGSRIVYKCPEGHMLLGDKSRHCKKDG---FWSGAPPSCKYVNCGGLTPIEDGDVALI 425
Y+ G ++ + C EG+ L+G++ +C+ G WSG PP C+ V C I++G
Sbjct: 117 YEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFS 176
Query: 426 DNRTTHGARAL-YSCR-----ENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSN 479
+ A+ YSC + F+L+G CGD +W AP C C P +
Sbjct: 177 EVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVENG 236
Query: 480 ASVTVNGHKAGSLAS--YTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPT 533
++ G K A+ + C+ G L GS ++ C W P C V+ + T
Sbjct: 237 KQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVSTSSTT 292
Score = 79.4 bits (187), Expect = 6e-14
Identities = 68/273 (24%), Positives = 103/273 (37%), Gaps = 28/273 (10%)
Query: 469 DWCPDPPAVSNASVTVNG---HKAGSLASYTCENGH--ILSGSTSVTCTLGGAWSGVPP- 522
D C +PP + ++ G Y C+ G+ I +T C W V
Sbjct: 33 DACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDD 92
Query: 523 SCKYVNCGTPTIH---KGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGK---W 576
+C C P I G V NGT +G F C Y+L G E L C G W
Sbjct: 93 ACYRETC--PYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIW 150
Query: 577 SYDIPSCELTSC-PEPEVPSGGY----MEAFDYYVHSTINFHCEAG-----HKLIGEPNL 626
S P CE C P P++ +G + +E F+Y + + C+ LIGE +
Sbjct: 151 SGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYL--DAVTYSCDPAPGPDPFSLIGESTI 208
Query: 627 VCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTT-HLGSVIQYSCTTNYRLVGPVR 685
C + WS +P C+ + C + P + G G + + + + C + L G
Sbjct: 209 YCGDNSVWSRAAPECKVVKC-RFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDT 267
Query: 686 RTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVS 718
C W P+C ++ S + S S
Sbjct: 268 IVCDSNSTWDPPVPKCLKVSTSSTTKSPASSAS 300
Score = 76.2 bits (179), Expect = 6e-13
Identities = 66/252 (26%), Positives = 100/252 (39%), Gaps = 45/252 (17%)
Query: 549 GSIAQFTCEPDYWLNG--AEELVCNRDGKW-SYDIPSCELTSCP---EP----EVPSGGY 598
G + C+ Y+ A +C+R+ W +C +CP +P VP+ G
Sbjct: 57 GERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGT 116
Query: 599 MEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGE---WSGDSPTCEYIDCGKLPTLPYG 655
E F Y +H F C G+ LIGE L C+ G WSG P CE + C P + G
Sbjct: 117 YE-FGYQMH----FICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNG 171
Query: 656 --TMELLNGTTHLGSVIQYSCTTN-----YRLVGPVRRTCTEEFQWSDSSPRCEEIRCSD 708
T + +L +V YSC + L+G C + WS ++P C+ ++C
Sbjct: 172 KHTFSEVEVFEYLDAVT-YSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRF 230
Query: 709 PIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCE 768
P+V +S G + A V + C+KG+ + G C+
Sbjct: 231 PVVENGKQIS-------------------GFGKKFYYKATVMFECDKGFYLDGSDTIVCD 271
Query: 769 DNGQWSGTTPTC 780
N W P C
Sbjct: 272 SNSTWDPPVPKC 283
Score = 55.2 bits (127), Expect = 1e-06
Identities = 32/124 (25%), Positives = 54/124 (43%), Gaps = 10/124 (8%)
Query: 353 CGSPDKLLNTTILGNDYDVGS---RIVYKC-----PEGHMLLGDKSRHCKKDGFWSGAPP 404
C P K+ N ++ +V + Y C P+ L+G+ + +C + WS A P
Sbjct: 162 CTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAP 221
Query: 405 SCKYVNCGGLTPIEDG-DVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEA 463
CK V C +E+G ++ + + A ++ C + F L G+ C WD
Sbjct: 222 ECKVVKCR-FPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPV 280
Query: 464 PRCL 467
P+CL
Sbjct: 281 PKCL 284
>EF076055-1|ABK81635.1| 384|Homo sapiens CD46 protein.
Length = 384
Score = 95.5 bits (227), Expect = 9e-19
Identities = 56/230 (24%), Positives = 97/230 (42%), Gaps = 15/230 (6%)
Query: 369 YDVGSRIVYKCPEGHMLLGDKSRH--CKKDGFWSG-APPSCKYVNCGGLTPIEDGDVALI 425
Y++G R+ YKC +G+ + + H C ++ W + +C C + +G
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA 113
Query: 426 DNRTTHGARALYSCRENFTLVGNPERTC---GDEGIWDGEAPRCLFDWCPDPPAVSNASV 482
+ G + + C E + L+G C G IW G+ P C C PP + N
Sbjct: 114 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKH 173
Query: 483 T---VNGHKAGSLASYTCE-----NGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTI 534
T V + +Y+C+ + L G +++ C WS P CK V C P +
Sbjct: 174 TFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVV 233
Query: 535 HKGSFVLINGTTTY-GSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSC 583
G + G Y + F C+ ++L+G++ +VC+ + W +P C
Sbjct: 234 ENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 92.3 bits (219), Expect = 9e-18
Identities = 54/177 (30%), Positives = 77/177 (43%), Gaps = 11/177 (6%)
Query: 742 TYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTCQYVDCGNPGRIENGKVTL 798
TY G + + C +GY +IGE + CE G WSG P C+ V C P +I+NGK T
Sbjct: 116 TYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTF 175
Query: 799 PSNATF-YGATAFYQCD-----ENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQI 852
F Y Y CD + + L G C +N WS P CK + C P +
Sbjct: 176 SEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPV--V 233
Query: 853 KAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRS 909
+ G + ++C++G+ L G T C S W+ VP C+ + S
Sbjct: 234 ENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVSTSS 290
Score = 84.2 bits (199), Expect = 2e-15
Identities = 60/229 (26%), Positives = 91/229 (39%), Gaps = 21/229 (9%)
Query: 432 GARALYSCRENFTLVGN--PERTCGDEGIW-DGEAPRCLFDWCP---DPPAVSNASVTVN 485
G R Y C++ + + C W C + CP DP ++ +V N
Sbjct: 57 GERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDP--LNGQAVPAN 114
Query: 486 G-HKAGSLASYTCENGHILSGSTSVTCTLGGA---WSGVPPSCKYVNCGTPT-IHKGSFV 540
G ++ G + C G+ L G + C L G+ WSG PP C+ V C P I G
Sbjct: 115 GTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHT 174
Query: 541 LINGTT-TYGSIAQFTCEP-----DYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVP 594
Y ++C+P + L G + C + WS P C++ C P V
Sbjct: 175 FSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVE 234
Query: 595 SGGYMEAFD--YYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTC 641
+G + F +Y +T+ F C+ G L G +VC + W P C
Sbjct: 235 NGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 81.4 bits (192), Expect = 2e-14
Identities = 64/244 (26%), Positives = 102/244 (41%), Gaps = 17/244 (6%)
Query: 743 YRIGALVKYRCEKGYKVIG--ESLSTCEDNGQWSGTT-PTCQYVDCGNPGRIENGKVTLP 799
Y IG V Y+C+KGY I + + C+ N W + C C NG+ +P
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQ-AVP 112
Query: 800 SNATF-YGATAFYQCDENWELEGVIRRMCQENGT---WSLEPPICKEITCPDPSAQIKAG 855
+N T+ +G + C+E + L G C+ G+ WS +PPIC+++ C P +IK G
Sbjct: 113 ANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLC-TPPPKIKNG 171
Query: 856 SGLLVVTSTLSIGGEAHYQCERG-----YNLKGHQTRTCISKGQWNGTVPVCIPIDCRSP 910
Y C+ ++L G T C W+ P C + CR P
Sbjct: 172 KHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFP 231
Query: 911 GNIENGKIVISNGSTL-FGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC-ELATNE 968
+ENGK + G + ++V + C + G C + W P C +++T+
Sbjct: 232 -VVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVSTSS 290
Query: 969 AVDS 972
S
Sbjct: 291 TTKS 294
Score = 81.4 bits (192), Expect = 2e-14
Identities = 49/176 (27%), Positives = 78/176 (44%), Gaps = 11/176 (6%)
Query: 369 YDVGSRIVYKCPEGHMLLGDKSRHCKKDG---FWSGAPPSCKYVNCGGLTPIEDGDVALI 425
Y+ G ++ + C EG+ L+G++ +C+ G WSG PP C+ V C I++G
Sbjct: 117 YEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFS 176
Query: 426 DNRTTHGARAL-YSCR-----ENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSN 479
+ A+ YSC + F+L+G CGD +W AP C C P +
Sbjct: 177 EVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVENG 236
Query: 480 ASVTVNGHKAGSLAS--YTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPT 533
++ G K A+ + C+ G L GS ++ C W P C V+ + T
Sbjct: 237 KQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVSTSSTT 292
Score = 79.4 bits (187), Expect = 6e-14
Identities = 68/273 (24%), Positives = 103/273 (37%), Gaps = 28/273 (10%)
Query: 469 DWCPDPPAVSNASVTVNG---HKAGSLASYTCENGH--ILSGSTSVTCTLGGAWSGVPP- 522
D C +PP + ++ G Y C+ G+ I +T C W V
Sbjct: 33 DACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDD 92
Query: 523 SCKYVNCGTPTIH---KGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGK---W 576
+C C P I G V NGT +G F C Y+L G E L C G W
Sbjct: 93 ACYRETC--PYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIW 150
Query: 577 SYDIPSCELTSC-PEPEVPSGGY----MEAFDYYVHSTINFHCEAG-----HKLIGEPNL 626
S P CE C P P++ +G + +E F+Y + + C+ LIGE +
Sbjct: 151 SGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYL--DAVTYSCDPAPGPDPFSLIGESTI 208
Query: 627 VCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTT-HLGSVIQYSCTTNYRLVGPVR 685
C + WS +P C+ + C + P + G G + + + + C + L G
Sbjct: 209 YCGDNSVWSRAAPECKVVKC-RFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDT 267
Query: 686 RTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVS 718
C W P+C ++ S + S S
Sbjct: 268 IVCDSNSTWDPPVPKCLKVSTSSTTKSPASSAS 300
Score = 76.2 bits (179), Expect = 6e-13
Identities = 66/252 (26%), Positives = 100/252 (39%), Gaps = 45/252 (17%)
Query: 549 GSIAQFTCEPDYWLNG--AEELVCNRDGKW-SYDIPSCELTSCP---EP----EVPSGGY 598
G + C+ Y+ A +C+R+ W +C +CP +P VP+ G
Sbjct: 57 GERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGT 116
Query: 599 MEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGE---WSGDSPTCEYIDCGKLPTLPYG 655
E F Y +H F C G+ LIGE L C+ G WSG P CE + C P + G
Sbjct: 117 YE-FGYQMH----FICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNG 171
Query: 656 --TMELLNGTTHLGSVIQYSCTTN-----YRLVGPVRRTCTEEFQWSDSSPRCEEIRCSD 708
T + +L +V YSC + L+G C + WS ++P C+ ++C
Sbjct: 172 KHTFSEVEVFEYLDAVT-YSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRF 230
Query: 709 PIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCE 768
P+V +S G + A V + C+KG+ + G C+
Sbjct: 231 PVVENGKQIS-------------------GFGKKFYYKATVMFECDKGFYLDGSDTIVCD 271
Query: 769 DNGQWSGTTPTC 780
N W P C
Sbjct: 272 SNSTWDPPVPKC 283
Score = 55.2 bits (127), Expect = 1e-06
Identities = 32/124 (25%), Positives = 54/124 (43%), Gaps = 10/124 (8%)
Query: 353 CGSPDKLLNTTILGNDYDVGS---RIVYKC-----PEGHMLLGDKSRHCKKDGFWSGAPP 404
C P K+ N ++ +V + Y C P+ L+G+ + +C + WS A P
Sbjct: 162 CTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAP 221
Query: 405 SCKYVNCGGLTPIEDG-DVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEA 463
CK V C +E+G ++ + + A ++ C + F L G+ C WD
Sbjct: 222 ECKVVKCR-FPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPV 280
Query: 464 PRCL 467
P+CL
Sbjct: 281 PKCL 284
>BC030594-1|AAH30594.1| 384|Homo sapiens CD46 molecule, complement
regulatory protein protein.
Length = 384
Score = 95.5 bits (227), Expect = 9e-19
Identities = 56/230 (24%), Positives = 97/230 (42%), Gaps = 15/230 (6%)
Query: 369 YDVGSRIVYKCPEGHMLLGDKSRH--CKKDGFWSG-APPSCKYVNCGGLTPIEDGDVALI 425
Y++G R+ YKC +G+ + + H C ++ W + +C C + +G
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA 113
Query: 426 DNRTTHGARALYSCRENFTLVGNPERTC---GDEGIWDGEAPRCLFDWCPDPPAVSNASV 482
+ G + + C E + L+G C G IW G+ P C C PP + N
Sbjct: 114 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKH 173
Query: 483 T---VNGHKAGSLASYTCE-----NGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTI 534
T V + +Y+C+ + L G +++ C WS P CK V C P +
Sbjct: 174 TFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVV 233
Query: 535 HKGSFVLINGTTTY-GSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSC 583
G + G Y + F C+ ++L+G++ +VC+ + W +P C
Sbjct: 234 ENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 92.3 bits (219), Expect = 9e-18
Identities = 54/177 (30%), Positives = 77/177 (43%), Gaps = 11/177 (6%)
Query: 742 TYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTCQYVDCGNPGRIENGKVTL 798
TY G + + C +GY +IGE + CE G WSG P C+ V C P +I+NGK T
Sbjct: 116 TYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTF 175
Query: 799 PSNATF-YGATAFYQCD-----ENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQI 852
F Y Y CD + + L G C +N WS P CK + C P +
Sbjct: 176 SEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPV--V 233
Query: 853 KAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRS 909
+ G + ++C++G+ L G T C S W+ VP C+ + S
Sbjct: 234 ENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVSTSS 290
Score = 84.2 bits (199), Expect = 2e-15
Identities = 60/229 (26%), Positives = 91/229 (39%), Gaps = 21/229 (9%)
Query: 432 GARALYSCRENFTLVGN--PERTCGDEGIW-DGEAPRCLFDWCP---DPPAVSNASVTVN 485
G R Y C++ + + C W C + CP DP ++ +V N
Sbjct: 57 GERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDP--LNGQAVPAN 114
Query: 486 G-HKAGSLASYTCENGHILSGSTSVTCTLGGA---WSGVPPSCKYVNCGTPT-IHKGSFV 540
G ++ G + C G+ L G + C L G+ WSG PP C+ V C P I G
Sbjct: 115 GTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHT 174
Query: 541 LINGTT-TYGSIAQFTCEP-----DYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVP 594
Y ++C+P + L G + C + WS P C++ C P V
Sbjct: 175 FSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVE 234
Query: 595 SGGYMEAFD--YYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTC 641
+G + F +Y +T+ F C+ G L G +VC + W P C
Sbjct: 235 NGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 81.4 bits (192), Expect = 2e-14
Identities = 64/244 (26%), Positives = 102/244 (41%), Gaps = 17/244 (6%)
Query: 743 YRIGALVKYRCEKGYKVIG--ESLSTCEDNGQWSGTT-PTCQYVDCGNPGRIENGKVTLP 799
Y IG V Y+C+KGY I + + C+ N W + C C NG+ +P
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQ-AVP 112
Query: 800 SNATF-YGATAFYQCDENWELEGVIRRMCQENGT---WSLEPPICKEITCPDPSAQIKAG 855
+N T+ +G + C+E + L G C+ G+ WS +PPIC+++ C P +IK G
Sbjct: 113 ANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLC-TPPPKIKNG 171
Query: 856 SGLLVVTSTLSIGGEAHYQCERG-----YNLKGHQTRTCISKGQWNGTVPVCIPIDCRSP 910
Y C+ ++L G T C W+ P C + CR P
Sbjct: 172 KHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFP 231
Query: 911 GNIENGKIVISNGSTL-FGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC-ELATNE 968
+ENGK + G + ++V + C + G C + W P C +++T+
Sbjct: 232 -VVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVSTSS 290
Query: 969 AVDS 972
S
Sbjct: 291 TTKS 294
Score = 81.4 bits (192), Expect = 2e-14
Identities = 49/176 (27%), Positives = 78/176 (44%), Gaps = 11/176 (6%)
Query: 369 YDVGSRIVYKCPEGHMLLGDKSRHCKKDG---FWSGAPPSCKYVNCGGLTPIEDGDVALI 425
Y+ G ++ + C EG+ L+G++ +C+ G WSG PP C+ V C I++G
Sbjct: 117 YEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFS 176
Query: 426 DNRTTHGARAL-YSCR-----ENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSN 479
+ A+ YSC + F+L+G CGD +W AP C C P +
Sbjct: 177 EVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVENG 236
Query: 480 ASVTVNGHKAGSLAS--YTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPT 533
++ G K A+ + C+ G L GS ++ C W P C V+ + T
Sbjct: 237 KQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVSTSSTT 292
Score = 79.4 bits (187), Expect = 6e-14
Identities = 68/273 (24%), Positives = 103/273 (37%), Gaps = 28/273 (10%)
Query: 469 DWCPDPPAVSNASVTVNG---HKAGSLASYTCENGH--ILSGSTSVTCTLGGAWSGVPP- 522
D C +PP + ++ G Y C+ G+ I +T C W V
Sbjct: 33 DACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDD 92
Query: 523 SCKYVNCGTPTIH---KGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGK---W 576
+C C P I G V NGT +G F C Y+L G E L C G W
Sbjct: 93 ACYRETC--PYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIW 150
Query: 577 SYDIPSCELTSC-PEPEVPSGGY----MEAFDYYVHSTINFHCEAG-----HKLIGEPNL 626
S P CE C P P++ +G + +E F+Y + + C+ LIGE +
Sbjct: 151 SGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYL--DAVTYSCDPAPGPDPFSLIGESTI 208
Query: 627 VCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTT-HLGSVIQYSCTTNYRLVGPVR 685
C + WS +P C+ + C + P + G G + + + + C + L G
Sbjct: 209 YCGDNSVWSRAAPECKVVKC-RFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDT 267
Query: 686 RTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVS 718
C W P+C ++ S + S S
Sbjct: 268 IVCDSNSTWDPPVPKCLKVSTSSTTKSPASSAS 300
Score = 76.2 bits (179), Expect = 6e-13
Identities = 66/252 (26%), Positives = 100/252 (39%), Gaps = 45/252 (17%)
Query: 549 GSIAQFTCEPDYWLNG--AEELVCNRDGKW-SYDIPSCELTSCP---EP----EVPSGGY 598
G + C+ Y+ A +C+R+ W +C +CP +P VP+ G
Sbjct: 57 GERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGT 116
Query: 599 MEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGE---WSGDSPTCEYIDCGKLPTLPYG 655
E F Y +H F C G+ LIGE L C+ G WSG P CE + C P + G
Sbjct: 117 YE-FGYQMH----FICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNG 171
Query: 656 --TMELLNGTTHLGSVIQYSCTTN-----YRLVGPVRRTCTEEFQWSDSSPRCEEIRCSD 708
T + +L +V YSC + L+G C + WS ++P C+ ++C
Sbjct: 172 KHTFSEVEVFEYLDAVT-YSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRF 230
Query: 709 PIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCE 768
P+V +S G + A V + C+KG+ + G C+
Sbjct: 231 PVVENGKQIS-------------------GFGKKFYYKATVMFECDKGFYLDGSDTIVCD 271
Query: 769 DNGQWSGTTPTC 780
N W P C
Sbjct: 272 SNSTWDPPVPKC 283
Score = 55.2 bits (127), Expect = 1e-06
Identities = 32/124 (25%), Positives = 54/124 (43%), Gaps = 10/124 (8%)
Query: 353 CGSPDKLLNTTILGNDYDVGS---RIVYKC-----PEGHMLLGDKSRHCKKDGFWSGAPP 404
C P K+ N ++ +V + Y C P+ L+G+ + +C + WS A P
Sbjct: 162 CTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAP 221
Query: 405 SCKYVNCGGLTPIEDG-DVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEA 463
CK V C +E+G ++ + + A ++ C + F L G+ C WD
Sbjct: 222 ECKVVKCR-FPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPV 280
Query: 464 PRCL 467
P+CL
Sbjct: 281 PKCL 284
>AY916779-1|AAW82433.1| 392|Homo sapiens membrane cofactor protein
(CD46, trophoblast-lymphocyte cross-reactive antigen)
protein.
Length = 392
Score = 95.5 bits (227), Expect = 9e-19
Identities = 56/230 (24%), Positives = 97/230 (42%), Gaps = 15/230 (6%)
Query: 369 YDVGSRIVYKCPEGHMLLGDKSRH--CKKDGFWSG-APPSCKYVNCGGLTPIEDGDVALI 425
Y++G R+ YKC +G+ + + H C ++ W + +C C + +G
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA 113
Query: 426 DNRTTHGARALYSCRENFTLVGNPERTC---GDEGIWDGEAPRCLFDWCPDPPAVSNASV 482
+ G + + C E + L+G C G IW G+ P C C PP + N
Sbjct: 114 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKH 173
Query: 483 T---VNGHKAGSLASYTCE-----NGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTI 534
T V + +Y+C+ + L G +++ C WS P CK V C P +
Sbjct: 174 TFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVV 233
Query: 535 HKGSFVLINGTTTY-GSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSC 583
G + G Y + F C+ ++L+G++ +VC+ + W +P C
Sbjct: 234 ENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 91.5 bits (217), Expect = 2e-17
Identities = 53/173 (30%), Positives = 76/173 (43%), Gaps = 11/173 (6%)
Query: 742 TYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTCQYVDCGNPGRIENGKVTL 798
TY G + + C +GY +IGE + CE G WSG P C+ V C P +I+NGK T
Sbjct: 116 TYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTF 175
Query: 799 PSNATF-YGATAFYQCD-----ENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQI 852
F Y Y CD + + L G C +N WS P CK + C P +
Sbjct: 176 SEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPV--V 233
Query: 853 KAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPI 905
+ G + ++C++G+ L G T C S W+ VP C+ +
Sbjct: 234 ENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKV 286
Score = 84.2 bits (199), Expect = 2e-15
Identities = 60/229 (26%), Positives = 91/229 (39%), Gaps = 21/229 (9%)
Query: 432 GARALYSCRENFTLVGN--PERTCGDEGIW-DGEAPRCLFDWCP---DPPAVSNASVTVN 485
G R Y C++ + + C W C + CP DP ++ +V N
Sbjct: 57 GERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDP--LNGQAVPAN 114
Query: 486 G-HKAGSLASYTCENGHILSGSTSVTCTLGGA---WSGVPPSCKYVNCGTPT-IHKGSFV 540
G ++ G + C G+ L G + C L G+ WSG PP C+ V C P I G
Sbjct: 115 GTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHT 174
Query: 541 LINGTT-TYGSIAQFTCEP-----DYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVP 594
Y ++C+P + L G + C + WS P C++ C P V
Sbjct: 175 FSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVE 234
Query: 595 SGGYMEAFD--YYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTC 641
+G + F +Y +T+ F C+ G L G +VC + W P C
Sbjct: 235 NGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 81.0 bits (191), Expect = 2e-14
Identities = 62/233 (26%), Positives = 96/233 (41%), Gaps = 16/233 (6%)
Query: 743 YRIGALVKYRCEKGYKVIG--ESLSTCEDNGQWSGTT-PTCQYVDCGNPGRIENGKVTLP 799
Y IG V Y+C+KGY I + + C+ N W + C C NG+ +P
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQ-AVP 112
Query: 800 SNATF-YGATAFYQCDENWELEGVIRRMCQENGT---WSLEPPICKEITCPDPSAQIKAG 855
+N T+ +G + C+E + L G C+ G+ WS +PPIC+++ C P +IK G
Sbjct: 113 ANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLC-TPPPKIKNG 171
Query: 856 SGLLVVTSTLSIGGEAHYQCERG-----YNLKGHQTRTCISKGQWNGTVPVCIPIDCRSP 910
Y C+ ++L G T C W+ P C + CR P
Sbjct: 172 KHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFP 231
Query: 911 GNIENGKIVISNGSTL-FGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
+ENGK + G + ++V + C + G C + W P C
Sbjct: 232 -VVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 79.8 bits (188), Expect = 5e-14
Identities = 63/255 (24%), Positives = 102/255 (40%), Gaps = 31/255 (12%)
Query: 604 YYVHSTINFHCEAGHKLIGE--PNLVCQQDGEWSGDSPTCEYID-CGKLPTLPYGTMELL 660
Y + +++ C+ G+ I + +C ++ W S Y + C + G
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA 113
Query: 661 NGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQ---WSDSSPRCEEIRCSDPIVAEKSIV 717
NGT G + + C Y L+G C + WS P CE++ C+ P +
Sbjct: 114 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNG-- 171
Query: 718 SVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKG-----YKVIGESLSTCEDNGQ 772
H + + + D V Y C+ + +IGES C DN
Sbjct: 172 -------KHTFSEVEVFEYLDA---------VTYSCDPAPGPDPFSLIGESTIYCGDNSV 215
Query: 773 WSGTTPTCQYVDCGNPGRIENGK-VTLPSNATFYGATAFYQCDENWELEGVIRRMCQENG 831
WS P C+ V C P +ENGK ++ +Y AT ++CD+ + L+G +C N
Sbjct: 216 WSRAAPECKVVKCRFPV-VENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNS 274
Query: 832 TWSLEPPICKEITCP 846
TW P C ++ P
Sbjct: 275 TWDPPVPKCLKVLPP 289
Score = 78.2 bits (184), Expect = 1e-13
Identities = 65/259 (25%), Positives = 99/259 (38%), Gaps = 28/259 (10%)
Query: 469 DWCPDPPAVSNASVTVNG---HKAGSLASYTCENGH--ILSGSTSVTCTLGGAWSGVPP- 522
D C +PP + ++ G Y C+ G+ I +T C W V
Sbjct: 33 DACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDD 92
Query: 523 SCKYVNCGTPTIH---KGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGK---W 576
+C C P I G V NGT +G F C Y+L G E L C G W
Sbjct: 93 ACYRETC--PYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIW 150
Query: 577 SYDIPSCELTSC-PEPEVPSGGY----MEAFDYYVHSTINFHCEAG-----HKLIGEPNL 626
S P CE C P P++ +G + +E F+Y + + C+ LIGE +
Sbjct: 151 SGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYL--DAVTYSCDPAPGPDPFSLIGESTI 208
Query: 627 VCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTT-HLGSVIQYSCTTNYRLVGPVR 685
C + WS +P C+ + C + P + G G + + + + C + L G
Sbjct: 209 YCGDNSVWSRAAPECKVVKC-RFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDT 267
Query: 686 RTCTEEFQWSDSSPRCEEI 704
C W P+C ++
Sbjct: 268 IVCDSNSTWDPPVPKCLKV 286
Score = 76.2 bits (179), Expect = 6e-13
Identities = 66/252 (26%), Positives = 100/252 (39%), Gaps = 45/252 (17%)
Query: 549 GSIAQFTCEPDYWLNG--AEELVCNRDGKW-SYDIPSCELTSCP---EP----EVPSGGY 598
G + C+ Y+ A +C+R+ W +C +CP +P VP+ G
Sbjct: 57 GERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGT 116
Query: 599 MEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGE---WSGDSPTCEYIDCGKLPTLPYG 655
E F Y +H F C G+ LIGE L C+ G WSG P CE + C P + G
Sbjct: 117 YE-FGYQMH----FICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNG 171
Query: 656 --TMELLNGTTHLGSVIQYSCTTN-----YRLVGPVRRTCTEEFQWSDSSPRCEEIRCSD 708
T + +L +V YSC + L+G C + WS ++P C+ ++C
Sbjct: 172 KHTFSEVEVFEYLDAVT-YSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRF 230
Query: 709 PIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCE 768
P+V +S G + A V + C+KG+ + G C+
Sbjct: 231 PVVENGKQIS-------------------GFGKKFYYKATVMFECDKGFYLDGSDTIVCD 271
Query: 769 DNGQWSGTTPTC 780
N W P C
Sbjct: 272 SNSTWDPPVPKC 283
Score = 60.9 bits (141), Expect = 2e-08
Identities = 40/149 (26%), Positives = 59/149 (39%), Gaps = 12/149 (8%)
Query: 826 MCQENGTW-SLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGH 884
+C N TW + C TCP + + + T G + H+ C GY L G
Sbjct: 79 ICDRNHTWLPVSDDACYRETCPYIRDPLNGQA--VPANGTYEFGYQMHFICNEGYYLIGE 136
Query: 885 QTRTCISKGQ---WNGTVPVCIPIDCRSPGNIENGKIVISNGSTL-FGSSVEYYC----- 935
+ C KG W+G P+C + C P I+NGK S + +V Y C
Sbjct: 137 EILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPG 196
Query: 936 LSQYQRVGPFLRKCLDDGRWSGEEPSCEL 964
+ +G C D+ WS P C++
Sbjct: 197 PDPFSLIGESTIYCGDNSVWSRAAPECKV 225
Score = 58.4 bits (135), Expect = 1e-07
Identities = 39/149 (26%), Positives = 66/149 (44%), Gaps = 13/149 (8%)
Query: 353 CGSPDKLLNTTILGNDYDVGS---RIVYKC-----PEGHMLLGDKSRHCKKDGFWSGAPP 404
C P K+ N ++ +V + Y C P+ L+G+ + +C + WS A P
Sbjct: 162 CTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAP 221
Query: 405 SCKYVNCGGLTPIEDG-DVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEA 463
CK V C +E+G ++ + + A ++ C + F L G+ C WD
Sbjct: 222 ECKVVKCR-FPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPV 280
Query: 464 PRCLFDWCPD---PPAVSNASVTVNGHKA 489
P+CL P PPA+S++ T + K+
Sbjct: 281 PKCLKVLPPSSTKPPALSHSVSTSSTTKS 309
>AL365178-7|CAH73952.1| 399|Homo sapiens CD46 molecule, complement
regulatory protein protein.
Length = 399
Score = 95.5 bits (227), Expect = 9e-19
Identities = 56/230 (24%), Positives = 97/230 (42%), Gaps = 15/230 (6%)
Query: 369 YDVGSRIVYKCPEGHMLLGDKSRH--CKKDGFWSG-APPSCKYVNCGGLTPIEDGDVALI 425
Y++G R+ YKC +G+ + + H C ++ W + +C C + +G
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA 113
Query: 426 DNRTTHGARALYSCRENFTLVGNPERTC---GDEGIWDGEAPRCLFDWCPDPPAVSNASV 482
+ G + + C E + L+G C G IW G+ P C C PP + N
Sbjct: 114 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKH 173
Query: 483 T---VNGHKAGSLASYTCE-----NGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTI 534
T V + +Y+C+ + L G +++ C WS P CK V C P +
Sbjct: 174 TFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVV 233
Query: 535 HKGSFVLINGTTTY-GSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSC 583
G + G Y + F C+ ++L+G++ +VC+ + W +P C
Sbjct: 234 ENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 91.5 bits (217), Expect = 2e-17
Identities = 53/173 (30%), Positives = 76/173 (43%), Gaps = 11/173 (6%)
Query: 742 TYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTCQYVDCGNPGRIENGKVTL 798
TY G + + C +GY +IGE + CE G WSG P C+ V C P +I+NGK T
Sbjct: 116 TYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTF 175
Query: 799 PSNATF-YGATAFYQCD-----ENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQI 852
F Y Y CD + + L G C +N WS P CK + C P +
Sbjct: 176 SEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPV--V 233
Query: 853 KAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPI 905
+ G + ++C++G+ L G T C S W+ VP C+ +
Sbjct: 234 ENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKV 286
Score = 84.2 bits (199), Expect = 2e-15
Identities = 60/229 (26%), Positives = 91/229 (39%), Gaps = 21/229 (9%)
Query: 432 GARALYSCRENFTLVGN--PERTCGDEGIW-DGEAPRCLFDWCP---DPPAVSNASVTVN 485
G R Y C++ + + C W C + CP DP ++ +V N
Sbjct: 57 GERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDP--LNGQAVPAN 114
Query: 486 G-HKAGSLASYTCENGHILSGSTSVTCTLGGA---WSGVPPSCKYVNCGTPT-IHKGSFV 540
G ++ G + C G+ L G + C L G+ WSG PP C+ V C P I G
Sbjct: 115 GTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHT 174
Query: 541 LINGTT-TYGSIAQFTCEP-----DYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVP 594
Y ++C+P + L G + C + WS P C++ C P V
Sbjct: 175 FSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVE 234
Query: 595 SGGYMEAFD--YYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTC 641
+G + F +Y +T+ F C+ G L G +VC + W P C
Sbjct: 235 NGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 81.0 bits (191), Expect = 2e-14
Identities = 62/233 (26%), Positives = 96/233 (41%), Gaps = 16/233 (6%)
Query: 743 YRIGALVKYRCEKGYKVIG--ESLSTCEDNGQWSGTT-PTCQYVDCGNPGRIENGKVTLP 799
Y IG V Y+C+KGY I + + C+ N W + C C NG+ +P
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQ-AVP 112
Query: 800 SNATF-YGATAFYQCDENWELEGVIRRMCQENGT---WSLEPPICKEITCPDPSAQIKAG 855
+N T+ +G + C+E + L G C+ G+ WS +PPIC+++ C P +IK G
Sbjct: 113 ANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLC-TPPPKIKNG 171
Query: 856 SGLLVVTSTLSIGGEAHYQCERG-----YNLKGHQTRTCISKGQWNGTVPVCIPIDCRSP 910
Y C+ ++L G T C W+ P C + CR P
Sbjct: 172 KHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFP 231
Query: 911 GNIENGKIVISNGSTL-FGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
+ENGK + G + ++V + C + G C + W P C
Sbjct: 232 -VVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 79.8 bits (188), Expect = 5e-14
Identities = 63/255 (24%), Positives = 102/255 (40%), Gaps = 31/255 (12%)
Query: 604 YYVHSTINFHCEAGHKLIGE--PNLVCQQDGEWSGDSPTCEYID-CGKLPTLPYGTMELL 660
Y + +++ C+ G+ I + +C ++ W S Y + C + G
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA 113
Query: 661 NGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQ---WSDSSPRCEEIRCSDPIVAEKSIV 717
NGT G + + C Y L+G C + WS P CE++ C+ P +
Sbjct: 114 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNG-- 171
Query: 718 SVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKG-----YKVIGESLSTCEDNGQ 772
H + + + D V Y C+ + +IGES C DN
Sbjct: 172 -------KHTFSEVEVFEYLDA---------VTYSCDPAPGPDPFSLIGESTIYCGDNSV 215
Query: 773 WSGTTPTCQYVDCGNPGRIENGK-VTLPSNATFYGATAFYQCDENWELEGVIRRMCQENG 831
WS P C+ V C P +ENGK ++ +Y AT ++CD+ + L+G +C N
Sbjct: 216 WSRAAPECKVVKCRFPV-VENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNS 274
Query: 832 TWSLEPPICKEITCP 846
TW P C ++ P
Sbjct: 275 TWDPPVPKCLKVLPP 289
Score = 78.2 bits (184), Expect = 1e-13
Identities = 65/259 (25%), Positives = 99/259 (38%), Gaps = 28/259 (10%)
Query: 469 DWCPDPPAVSNASVTVNG---HKAGSLASYTCENGH--ILSGSTSVTCTLGGAWSGVPP- 522
D C +PP + ++ G Y C+ G+ I +T C W V
Sbjct: 33 DACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDD 92
Query: 523 SCKYVNCGTPTIH---KGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGK---W 576
+C C P I G V NGT +G F C Y+L G E L C G W
Sbjct: 93 ACYRETC--PYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIW 150
Query: 577 SYDIPSCELTSC-PEPEVPSGGY----MEAFDYYVHSTINFHCEAG-----HKLIGEPNL 626
S P CE C P P++ +G + +E F+Y + + C+ LIGE +
Sbjct: 151 SGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYL--DAVTYSCDPAPGPDPFSLIGESTI 208
Query: 627 VCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTT-HLGSVIQYSCTTNYRLVGPVR 685
C + WS +P C+ + C + P + G G + + + + C + L G
Sbjct: 209 YCGDNSVWSRAAPECKVVKC-RFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDT 267
Query: 686 RTCTEEFQWSDSSPRCEEI 704
C W P+C ++
Sbjct: 268 IVCDSNSTWDPPVPKCLKV 286
Score = 76.2 bits (179), Expect = 6e-13
Identities = 66/252 (26%), Positives = 100/252 (39%), Gaps = 45/252 (17%)
Query: 549 GSIAQFTCEPDYWLNG--AEELVCNRDGKW-SYDIPSCELTSCP---EP----EVPSGGY 598
G + C+ Y+ A +C+R+ W +C +CP +P VP+ G
Sbjct: 57 GERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGT 116
Query: 599 MEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGE---WSGDSPTCEYIDCGKLPTLPYG 655
E F Y +H F C G+ LIGE L C+ G WSG P CE + C P + G
Sbjct: 117 YE-FGYQMH----FICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNG 171
Query: 656 --TMELLNGTTHLGSVIQYSCTTN-----YRLVGPVRRTCTEEFQWSDSSPRCEEIRCSD 708
T + +L +V YSC + L+G C + WS ++P C+ ++C
Sbjct: 172 KHTFSEVEVFEYLDAVT-YSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRF 230
Query: 709 PIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCE 768
P+V +S G + A V + C+KG+ + G C+
Sbjct: 231 PVVENGKQIS-------------------GFGKKFYYKATVMFECDKGFYLDGSDTIVCD 271
Query: 769 DNGQWSGTTPTC 780
N W P C
Sbjct: 272 SNSTWDPPVPKC 283
Score = 60.9 bits (141), Expect = 2e-08
Identities = 40/149 (26%), Positives = 59/149 (39%), Gaps = 12/149 (8%)
Query: 826 MCQENGTW-SLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGH 884
+C N TW + C TCP + + + T G + H+ C GY L G
Sbjct: 79 ICDRNHTWLPVSDDACYRETCPYIRDPLNGQA--VPANGTYEFGYQMHFICNEGYYLIGE 136
Query: 885 QTRTCISKGQ---WNGTVPVCIPIDCRSPGNIENGKIVISNGSTL-FGSSVEYYC----- 935
+ C KG W+G P+C + C P I+NGK S + +V Y C
Sbjct: 137 EILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPG 196
Query: 936 LSQYQRVGPFLRKCLDDGRWSGEEPSCEL 964
+ +G C D+ WS P C++
Sbjct: 197 PDPFSLIGESTIYCGDNSVWSRAAPECKV 225
Score = 58.4 bits (135), Expect = 1e-07
Identities = 39/149 (26%), Positives = 66/149 (44%), Gaps = 13/149 (8%)
Query: 353 CGSPDKLLNTTILGNDYDVGS---RIVYKC-----PEGHMLLGDKSRHCKKDGFWSGAPP 404
C P K+ N ++ +V + Y C P+ L+G+ + +C + WS A P
Sbjct: 162 CTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAP 221
Query: 405 SCKYVNCGGLTPIEDG-DVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEA 463
CK V C +E+G ++ + + A ++ C + F L G+ C WD
Sbjct: 222 ECKVVKCR-FPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPV 280
Query: 464 PRCLFDWCPD---PPAVSNASVTVNGHKA 489
P+CL P PPA+S++ T + K+
Sbjct: 281 PKCLKVLPPSSTKPPALSHSVSTSSTTKS 309
>AL365178-5|CAH73951.1| 384|Homo sapiens CD46 molecule, complement
regulatory protein protein.
Length = 384
Score = 95.5 bits (227), Expect = 9e-19
Identities = 56/230 (24%), Positives = 97/230 (42%), Gaps = 15/230 (6%)
Query: 369 YDVGSRIVYKCPEGHMLLGDKSRH--CKKDGFWSG-APPSCKYVNCGGLTPIEDGDVALI 425
Y++G R+ YKC +G+ + + H C ++ W + +C C + +G
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA 113
Query: 426 DNRTTHGARALYSCRENFTLVGNPERTC---GDEGIWDGEAPRCLFDWCPDPPAVSNASV 482
+ G + + C E + L+G C G IW G+ P C C PP + N
Sbjct: 114 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKH 173
Query: 483 T---VNGHKAGSLASYTCE-----NGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTI 534
T V + +Y+C+ + L G +++ C WS P CK V C P +
Sbjct: 174 TFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVV 233
Query: 535 HKGSFVLINGTTTY-GSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSC 583
G + G Y + F C+ ++L+G++ +VC+ + W +P C
Sbjct: 234 ENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 92.3 bits (219), Expect = 9e-18
Identities = 54/177 (30%), Positives = 77/177 (43%), Gaps = 11/177 (6%)
Query: 742 TYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTCQYVDCGNPGRIENGKVTL 798
TY G + + C +GY +IGE + CE G WSG P C+ V C P +I+NGK T
Sbjct: 116 TYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTF 175
Query: 799 PSNATF-YGATAFYQCD-----ENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQI 852
F Y Y CD + + L G C +N WS P CK + C P +
Sbjct: 176 SEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPV--V 233
Query: 853 KAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRS 909
+ G + ++C++G+ L G T C S W+ VP C+ + S
Sbjct: 234 ENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVSTSS 290
Score = 84.2 bits (199), Expect = 2e-15
Identities = 60/229 (26%), Positives = 91/229 (39%), Gaps = 21/229 (9%)
Query: 432 GARALYSCRENFTLVGN--PERTCGDEGIW-DGEAPRCLFDWCP---DPPAVSNASVTVN 485
G R Y C++ + + C W C + CP DP ++ +V N
Sbjct: 57 GERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDP--LNGQAVPAN 114
Query: 486 G-HKAGSLASYTCENGHILSGSTSVTCTLGGA---WSGVPPSCKYVNCGTPT-IHKGSFV 540
G ++ G + C G+ L G + C L G+ WSG PP C+ V C P I G
Sbjct: 115 GTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHT 174
Query: 541 LINGTT-TYGSIAQFTCEP-----DYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVP 594
Y ++C+P + L G + C + WS P C++ C P V
Sbjct: 175 FSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVE 234
Query: 595 SGGYMEAFD--YYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTC 641
+G + F +Y +T+ F C+ G L G +VC + W P C
Sbjct: 235 NGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 81.4 bits (192), Expect = 2e-14
Identities = 64/244 (26%), Positives = 102/244 (41%), Gaps = 17/244 (6%)
Query: 743 YRIGALVKYRCEKGYKVIG--ESLSTCEDNGQWSGTT-PTCQYVDCGNPGRIENGKVTLP 799
Y IG V Y+C+KGY I + + C+ N W + C C NG+ +P
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQ-AVP 112
Query: 800 SNATF-YGATAFYQCDENWELEGVIRRMCQENGT---WSLEPPICKEITCPDPSAQIKAG 855
+N T+ +G + C+E + L G C+ G+ WS +PPIC+++ C P +IK G
Sbjct: 113 ANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLC-TPPPKIKNG 171
Query: 856 SGLLVVTSTLSIGGEAHYQCERG-----YNLKGHQTRTCISKGQWNGTVPVCIPIDCRSP 910
Y C+ ++L G T C W+ P C + CR P
Sbjct: 172 KHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFP 231
Query: 911 GNIENGKIVISNGSTL-FGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC-ELATNE 968
+ENGK + G + ++V + C + G C + W P C +++T+
Sbjct: 232 -VVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVSTSS 290
Query: 969 AVDS 972
S
Sbjct: 291 TTKS 294
Score = 81.4 bits (192), Expect = 2e-14
Identities = 49/176 (27%), Positives = 78/176 (44%), Gaps = 11/176 (6%)
Query: 369 YDVGSRIVYKCPEGHMLLGDKSRHCKKDG---FWSGAPPSCKYVNCGGLTPIEDGDVALI 425
Y+ G ++ + C EG+ L+G++ +C+ G WSG PP C+ V C I++G
Sbjct: 117 YEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFS 176
Query: 426 DNRTTHGARAL-YSCR-----ENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSN 479
+ A+ YSC + F+L+G CGD +W AP C C P +
Sbjct: 177 EVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVENG 236
Query: 480 ASVTVNGHKAGSLAS--YTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPT 533
++ G K A+ + C+ G L GS ++ C W P C V+ + T
Sbjct: 237 KQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVSTSSTT 292
Score = 79.4 bits (187), Expect = 6e-14
Identities = 68/273 (24%), Positives = 103/273 (37%), Gaps = 28/273 (10%)
Query: 469 DWCPDPPAVSNASVTVNG---HKAGSLASYTCENGH--ILSGSTSVTCTLGGAWSGVPP- 522
D C +PP + ++ G Y C+ G+ I +T C W V
Sbjct: 33 DACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDD 92
Query: 523 SCKYVNCGTPTIH---KGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGK---W 576
+C C P I G V NGT +G F C Y+L G E L C G W
Sbjct: 93 ACYRETC--PYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIW 150
Query: 577 SYDIPSCELTSC-PEPEVPSGGY----MEAFDYYVHSTINFHCEAG-----HKLIGEPNL 626
S P CE C P P++ +G + +E F+Y + + C+ LIGE +
Sbjct: 151 SGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYL--DAVTYSCDPAPGPDPFSLIGESTI 208
Query: 627 VCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTT-HLGSVIQYSCTTNYRLVGPVR 685
C + WS +P C+ + C + P + G G + + + + C + L G
Sbjct: 209 YCGDNSVWSRAAPECKVVKC-RFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDT 267
Query: 686 RTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVS 718
C W P+C ++ S + S S
Sbjct: 268 IVCDSNSTWDPPVPKCLKVSTSSTTKSPASSAS 300
Score = 76.2 bits (179), Expect = 6e-13
Identities = 66/252 (26%), Positives = 100/252 (39%), Gaps = 45/252 (17%)
Query: 549 GSIAQFTCEPDYWLNG--AEELVCNRDGKW-SYDIPSCELTSCP---EP----EVPSGGY 598
G + C+ Y+ A +C+R+ W +C +CP +P VP+ G
Sbjct: 57 GERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGT 116
Query: 599 MEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGE---WSGDSPTCEYIDCGKLPTLPYG 655
E F Y +H F C G+ LIGE L C+ G WSG P CE + C P + G
Sbjct: 117 YE-FGYQMH----FICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNG 171
Query: 656 --TMELLNGTTHLGSVIQYSCTTN-----YRLVGPVRRTCTEEFQWSDSSPRCEEIRCSD 708
T + +L +V YSC + L+G C + WS ++P C+ ++C
Sbjct: 172 KHTFSEVEVFEYLDAVT-YSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRF 230
Query: 709 PIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCE 768
P+V +S G + A V + C+KG+ + G C+
Sbjct: 231 PVVENGKQIS-------------------GFGKKFYYKATVMFECDKGFYLDGSDTIVCD 271
Query: 769 DNGQWSGTTPTC 780
N W P C
Sbjct: 272 SNSTWDPPVPKC 283
Score = 55.2 bits (127), Expect = 1e-06
Identities = 32/124 (25%), Positives = 54/124 (43%), Gaps = 10/124 (8%)
Query: 353 CGSPDKLLNTTILGNDYDVGS---RIVYKC-----PEGHMLLGDKSRHCKKDGFWSGAPP 404
C P K+ N ++ +V + Y C P+ L+G+ + +C + WS A P
Sbjct: 162 CTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAP 221
Query: 405 SCKYVNCGGLTPIEDG-DVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEA 463
CK V C +E+G ++ + + A ++ C + F L G+ C WD
Sbjct: 222 ECKVVKCR-FPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPV 280
Query: 464 PRCL 467
P+CL
Sbjct: 281 PKCL 284
>AL365178-3|CAH73947.1| 392|Homo sapiens CD46 molecule, complement
regulatory protein protein.
Length = 392
Score = 95.5 bits (227), Expect = 9e-19
Identities = 56/230 (24%), Positives = 97/230 (42%), Gaps = 15/230 (6%)
Query: 369 YDVGSRIVYKCPEGHMLLGDKSRH--CKKDGFWSG-APPSCKYVNCGGLTPIEDGDVALI 425
Y++G R+ YKC +G+ + + H C ++ W + +C C + +G
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA 113
Query: 426 DNRTTHGARALYSCRENFTLVGNPERTC---GDEGIWDGEAPRCLFDWCPDPPAVSNASV 482
+ G + + C E + L+G C G IW G+ P C C PP + N
Sbjct: 114 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKH 173
Query: 483 T---VNGHKAGSLASYTCE-----NGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTI 534
T V + +Y+C+ + L G +++ C WS P CK V C P +
Sbjct: 174 TFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVV 233
Query: 535 HKGSFVLINGTTTY-GSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSC 583
G + G Y + F C+ ++L+G++ +VC+ + W +P C
Sbjct: 234 ENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 91.5 bits (217), Expect = 2e-17
Identities = 53/173 (30%), Positives = 76/173 (43%), Gaps = 11/173 (6%)
Query: 742 TYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTCQYVDCGNPGRIENGKVTL 798
TY G + + C +GY +IGE + CE G WSG P C+ V C P +I+NGK T
Sbjct: 116 TYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTF 175
Query: 799 PSNATF-YGATAFYQCD-----ENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQI 852
F Y Y CD + + L G C +N WS P CK + C P +
Sbjct: 176 SEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPV--V 233
Query: 853 KAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPI 905
+ G + ++C++G+ L G T C S W+ VP C+ +
Sbjct: 234 ENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKV 286
Score = 84.2 bits (199), Expect = 2e-15
Identities = 60/229 (26%), Positives = 91/229 (39%), Gaps = 21/229 (9%)
Query: 432 GARALYSCRENFTLVGN--PERTCGDEGIW-DGEAPRCLFDWCP---DPPAVSNASVTVN 485
G R Y C++ + + C W C + CP DP ++ +V N
Sbjct: 57 GERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDP--LNGQAVPAN 114
Query: 486 G-HKAGSLASYTCENGHILSGSTSVTCTLGGA---WSGVPPSCKYVNCGTPT-IHKGSFV 540
G ++ G + C G+ L G + C L G+ WSG PP C+ V C P I G
Sbjct: 115 GTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHT 174
Query: 541 LINGTT-TYGSIAQFTCEP-----DYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVP 594
Y ++C+P + L G + C + WS P C++ C P V
Sbjct: 175 FSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVE 234
Query: 595 SGGYMEAFD--YYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTC 641
+G + F +Y +T+ F C+ G L G +VC + W P C
Sbjct: 235 NGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 81.0 bits (191), Expect = 2e-14
Identities = 62/233 (26%), Positives = 96/233 (41%), Gaps = 16/233 (6%)
Query: 743 YRIGALVKYRCEKGYKVIG--ESLSTCEDNGQWSGTT-PTCQYVDCGNPGRIENGKVTLP 799
Y IG V Y+C+KGY I + + C+ N W + C C NG+ +P
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQ-AVP 112
Query: 800 SNATF-YGATAFYQCDENWELEGVIRRMCQENGT---WSLEPPICKEITCPDPSAQIKAG 855
+N T+ +G + C+E + L G C+ G+ WS +PPIC+++ C P +IK G
Sbjct: 113 ANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLC-TPPPKIKNG 171
Query: 856 SGLLVVTSTLSIGGEAHYQCERG-----YNLKGHQTRTCISKGQWNGTVPVCIPIDCRSP 910
Y C+ ++L G T C W+ P C + CR P
Sbjct: 172 KHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFP 231
Query: 911 GNIENGKIVISNGSTL-FGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
+ENGK + G + ++V + C + G C + W P C
Sbjct: 232 -VVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 79.8 bits (188), Expect = 5e-14
Identities = 63/255 (24%), Positives = 102/255 (40%), Gaps = 31/255 (12%)
Query: 604 YYVHSTINFHCEAGHKLIGE--PNLVCQQDGEWSGDSPTCEYID-CGKLPTLPYGTMELL 660
Y + +++ C+ G+ I + +C ++ W S Y + C + G
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA 113
Query: 661 NGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQ---WSDSSPRCEEIRCSDPIVAEKSIV 717
NGT G + + C Y L+G C + WS P CE++ C+ P +
Sbjct: 114 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNG-- 171
Query: 718 SVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKG-----YKVIGESLSTCEDNGQ 772
H + + + D V Y C+ + +IGES C DN
Sbjct: 172 -------KHTFSEVEVFEYLDA---------VTYSCDPAPGPDPFSLIGESTIYCGDNSV 215
Query: 773 WSGTTPTCQYVDCGNPGRIENGK-VTLPSNATFYGATAFYQCDENWELEGVIRRMCQENG 831
WS P C+ V C P +ENGK ++ +Y AT ++CD+ + L+G +C N
Sbjct: 216 WSRAAPECKVVKCRFPV-VENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNS 274
Query: 832 TWSLEPPICKEITCP 846
TW P C ++ P
Sbjct: 275 TWDPPVPKCLKVLPP 289
Score = 78.2 bits (184), Expect = 1e-13
Identities = 65/259 (25%), Positives = 99/259 (38%), Gaps = 28/259 (10%)
Query: 469 DWCPDPPAVSNASVTVNG---HKAGSLASYTCENGH--ILSGSTSVTCTLGGAWSGVPP- 522
D C +PP + ++ G Y C+ G+ I +T C W V
Sbjct: 33 DACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDD 92
Query: 523 SCKYVNCGTPTIH---KGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGK---W 576
+C C P I G V NGT +G F C Y+L G E L C G W
Sbjct: 93 ACYRETC--PYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIW 150
Query: 577 SYDIPSCELTSC-PEPEVPSGGY----MEAFDYYVHSTINFHCEAG-----HKLIGEPNL 626
S P CE C P P++ +G + +E F+Y + + C+ LIGE +
Sbjct: 151 SGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYL--DAVTYSCDPAPGPDPFSLIGESTI 208
Query: 627 VCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTT-HLGSVIQYSCTTNYRLVGPVR 685
C + WS +P C+ + C + P + G G + + + + C + L G
Sbjct: 209 YCGDNSVWSRAAPECKVVKC-RFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDT 267
Query: 686 RTCTEEFQWSDSSPRCEEI 704
C W P+C ++
Sbjct: 268 IVCDSNSTWDPPVPKCLKV 286
Score = 76.2 bits (179), Expect = 6e-13
Identities = 66/252 (26%), Positives = 100/252 (39%), Gaps = 45/252 (17%)
Query: 549 GSIAQFTCEPDYWLNG--AEELVCNRDGKW-SYDIPSCELTSCP---EP----EVPSGGY 598
G + C+ Y+ A +C+R+ W +C +CP +P VP+ G
Sbjct: 57 GERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGT 116
Query: 599 MEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGE---WSGDSPTCEYIDCGKLPTLPYG 655
E F Y +H F C G+ LIGE L C+ G WSG P CE + C P + G
Sbjct: 117 YE-FGYQMH----FICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNG 171
Query: 656 --TMELLNGTTHLGSVIQYSCTTN-----YRLVGPVRRTCTEEFQWSDSSPRCEEIRCSD 708
T + +L +V YSC + L+G C + WS ++P C+ ++C
Sbjct: 172 KHTFSEVEVFEYLDAVT-YSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRF 230
Query: 709 PIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCE 768
P+V +S G + A V + C+KG+ + G C+
Sbjct: 231 PVVENGKQIS-------------------GFGKKFYYKATVMFECDKGFYLDGSDTIVCD 271
Query: 769 DNGQWSGTTPTC 780
N W P C
Sbjct: 272 SNSTWDPPVPKC 283
Score = 60.9 bits (141), Expect = 2e-08
Identities = 40/149 (26%), Positives = 59/149 (39%), Gaps = 12/149 (8%)
Query: 826 MCQENGTW-SLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGH 884
+C N TW + C TCP + + + T G + H+ C GY L G
Sbjct: 79 ICDRNHTWLPVSDDACYRETCPYIRDPLNGQA--VPANGTYEFGYQMHFICNEGYYLIGE 136
Query: 885 QTRTCISKGQ---WNGTVPVCIPIDCRSPGNIENGKIVISNGSTL-FGSSVEYYC----- 935
+ C KG W+G P+C + C P I+NGK S + +V Y C
Sbjct: 137 EILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPG 196
Query: 936 LSQYQRVGPFLRKCLDDGRWSGEEPSCEL 964
+ +G C D+ WS P C++
Sbjct: 197 PDPFSLIGESTIYCGDNSVWSRAAPECKV 225
Score = 58.4 bits (135), Expect = 1e-07
Identities = 39/149 (26%), Positives = 66/149 (44%), Gaps = 13/149 (8%)
Query: 353 CGSPDKLLNTTILGNDYDVGS---RIVYKC-----PEGHMLLGDKSRHCKKDGFWSGAPP 404
C P K+ N ++ +V + Y C P+ L+G+ + +C + WS A P
Sbjct: 162 CTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAP 221
Query: 405 SCKYVNCGGLTPIEDG-DVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEA 463
CK V C +E+G ++ + + A ++ C + F L G+ C WD
Sbjct: 222 ECKVVKCR-FPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPV 280
Query: 464 PRCLFDWCPD---PPAVSNASVTVNGHKA 489
P+CL P PPA+S++ T + K+
Sbjct: 281 PKCLKVLPPSSTKPPALSHSVSTSSTTKS 309
>AL365178-2|CAH73948.1| 377|Homo sapiens CD46 molecule, complement
regulatory protein protein.
Length = 377
Score = 95.5 bits (227), Expect = 9e-19
Identities = 56/230 (24%), Positives = 97/230 (42%), Gaps = 15/230 (6%)
Query: 369 YDVGSRIVYKCPEGHMLLGDKSRH--CKKDGFWSG-APPSCKYVNCGGLTPIEDGDVALI 425
Y++G R+ YKC +G+ + + H C ++ W + +C C + +G
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA 113
Query: 426 DNRTTHGARALYSCRENFTLVGNPERTC---GDEGIWDGEAPRCLFDWCPDPPAVSNASV 482
+ G + + C E + L+G C G IW G+ P C C PP + N
Sbjct: 114 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKH 173
Query: 483 T---VNGHKAGSLASYTCE-----NGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTI 534
T V + +Y+C+ + L G +++ C WS P CK V C P +
Sbjct: 174 TFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVV 233
Query: 535 HKGSFVLINGTTTY-GSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSC 583
G + G Y + F C+ ++L+G++ +VC+ + W +P C
Sbjct: 234 ENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 92.3 bits (219), Expect = 9e-18
Identities = 54/177 (30%), Positives = 77/177 (43%), Gaps = 11/177 (6%)
Query: 742 TYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTCQYVDCGNPGRIENGKVTL 798
TY G + + C +GY +IGE + CE G WSG P C+ V C P +I+NGK T
Sbjct: 116 TYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTF 175
Query: 799 PSNATF-YGATAFYQCD-----ENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQI 852
F Y Y CD + + L G C +N WS P CK + C P +
Sbjct: 176 SEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPV--V 233
Query: 853 KAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRS 909
+ G + ++C++G+ L G T C S W+ VP C+ + S
Sbjct: 234 ENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVSTSS 290
Score = 84.2 bits (199), Expect = 2e-15
Identities = 60/229 (26%), Positives = 91/229 (39%), Gaps = 21/229 (9%)
Query: 432 GARALYSCRENFTLVGN--PERTCGDEGIW-DGEAPRCLFDWCP---DPPAVSNASVTVN 485
G R Y C++ + + C W C + CP DP ++ +V N
Sbjct: 57 GERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDP--LNGQAVPAN 114
Query: 486 G-HKAGSLASYTCENGHILSGSTSVTCTLGGA---WSGVPPSCKYVNCGTPT-IHKGSFV 540
G ++ G + C G+ L G + C L G+ WSG PP C+ V C P I G
Sbjct: 115 GTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHT 174
Query: 541 LINGTT-TYGSIAQFTCEP-----DYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVP 594
Y ++C+P + L G + C + WS P C++ C P V
Sbjct: 175 FSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVE 234
Query: 595 SGGYMEAFD--YYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTC 641
+G + F +Y +T+ F C+ G L G +VC + W P C
Sbjct: 235 NGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 81.4 bits (192), Expect = 2e-14
Identities = 64/244 (26%), Positives = 102/244 (41%), Gaps = 17/244 (6%)
Query: 743 YRIGALVKYRCEKGYKVIG--ESLSTCEDNGQWSGTT-PTCQYVDCGNPGRIENGKVTLP 799
Y IG V Y+C+KGY I + + C+ N W + C C NG+ +P
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQ-AVP 112
Query: 800 SNATF-YGATAFYQCDENWELEGVIRRMCQENGT---WSLEPPICKEITCPDPSAQIKAG 855
+N T+ +G + C+E + L G C+ G+ WS +PPIC+++ C P +IK G
Sbjct: 113 ANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLC-TPPPKIKNG 171
Query: 856 SGLLVVTSTLSIGGEAHYQCERG-----YNLKGHQTRTCISKGQWNGTVPVCIPIDCRSP 910
Y C+ ++L G T C W+ P C + CR P
Sbjct: 172 KHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFP 231
Query: 911 GNIENGKIVISNGSTL-FGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC-ELATNE 968
+ENGK + G + ++V + C + G C + W P C +++T+
Sbjct: 232 -VVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVSTSS 290
Query: 969 AVDS 972
S
Sbjct: 291 TTKS 294
Score = 81.4 bits (192), Expect = 2e-14
Identities = 49/176 (27%), Positives = 78/176 (44%), Gaps = 11/176 (6%)
Query: 369 YDVGSRIVYKCPEGHMLLGDKSRHCKKDG---FWSGAPPSCKYVNCGGLTPIEDGDVALI 425
Y+ G ++ + C EG+ L+G++ +C+ G WSG PP C+ V C I++G
Sbjct: 117 YEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFS 176
Query: 426 DNRTTHGARAL-YSCR-----ENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSN 479
+ A+ YSC + F+L+G CGD +W AP C C P +
Sbjct: 177 EVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVENG 236
Query: 480 ASVTVNGHKAGSLAS--YTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPT 533
++ G K A+ + C+ G L GS ++ C W P C V+ + T
Sbjct: 237 KQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVSTSSTT 292
Score = 79.4 bits (187), Expect = 6e-14
Identities = 68/273 (24%), Positives = 103/273 (37%), Gaps = 28/273 (10%)
Query: 469 DWCPDPPAVSNASVTVNG---HKAGSLASYTCENGH--ILSGSTSVTCTLGGAWSGVPP- 522
D C +PP + ++ G Y C+ G+ I +T C W V
Sbjct: 33 DACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDD 92
Query: 523 SCKYVNCGTPTIH---KGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGK---W 576
+C C P I G V NGT +G F C Y+L G E L C G W
Sbjct: 93 ACYRETC--PYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIW 150
Query: 577 SYDIPSCELTSC-PEPEVPSGGY----MEAFDYYVHSTINFHCEAG-----HKLIGEPNL 626
S P CE C P P++ +G + +E F+Y + + C+ LIGE +
Sbjct: 151 SGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYL--DAVTYSCDPAPGPDPFSLIGESTI 208
Query: 627 VCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTT-HLGSVIQYSCTTNYRLVGPVR 685
C + WS +P C+ + C + P + G G + + + + C + L G
Sbjct: 209 YCGDNSVWSRAAPECKVVKC-RFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDT 267
Query: 686 RTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVS 718
C W P+C ++ S + S S
Sbjct: 268 IVCDSNSTWDPPVPKCLKVSTSSTTKSPASSAS 300
Score = 76.2 bits (179), Expect = 6e-13
Identities = 66/252 (26%), Positives = 100/252 (39%), Gaps = 45/252 (17%)
Query: 549 GSIAQFTCEPDYWLNG--AEELVCNRDGKW-SYDIPSCELTSCP---EP----EVPSGGY 598
G + C+ Y+ A +C+R+ W +C +CP +P VP+ G
Sbjct: 57 GERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGT 116
Query: 599 MEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGE---WSGDSPTCEYIDCGKLPTLPYG 655
E F Y +H F C G+ LIGE L C+ G WSG P CE + C P + G
Sbjct: 117 YE-FGYQMH----FICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNG 171
Query: 656 --TMELLNGTTHLGSVIQYSCTTN-----YRLVGPVRRTCTEEFQWSDSSPRCEEIRCSD 708
T + +L +V YSC + L+G C + WS ++P C+ ++C
Sbjct: 172 KHTFSEVEVFEYLDAVT-YSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRF 230
Query: 709 PIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCE 768
P+V +S G + A V + C+KG+ + G C+
Sbjct: 231 PVVENGKQIS-------------------GFGKKFYYKATVMFECDKGFYLDGSDTIVCD 271
Query: 769 DNGQWSGTTPTC 780
N W P C
Sbjct: 272 SNSTWDPPVPKC 283
Score = 55.2 bits (127), Expect = 1e-06
Identities = 32/124 (25%), Positives = 54/124 (43%), Gaps = 10/124 (8%)
Query: 353 CGSPDKLLNTTILGNDYDVGS---RIVYKC-----PEGHMLLGDKSRHCKKDGFWSGAPP 404
C P K+ N ++ +V + Y C P+ L+G+ + +C + WS A P
Sbjct: 162 CTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAP 221
Query: 405 SCKYVNCGGLTPIEDG-DVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEA 463
CK V C +E+G ++ + + A ++ C + F L G+ C WD
Sbjct: 222 ECKVVKCR-FPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPV 280
Query: 464 PRCL 467
P+CL
Sbjct: 281 PKCL 284
>AL035209-8|CAI18810.1| 399|Homo sapiens CD46 molecule, complement
regulatory protein protein.
Length = 399
Score = 95.5 bits (227), Expect = 9e-19
Identities = 56/230 (24%), Positives = 97/230 (42%), Gaps = 15/230 (6%)
Query: 369 YDVGSRIVYKCPEGHMLLGDKSRH--CKKDGFWSG-APPSCKYVNCGGLTPIEDGDVALI 425
Y++G R+ YKC +G+ + + H C ++ W + +C C + +G
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA 113
Query: 426 DNRTTHGARALYSCRENFTLVGNPERTC---GDEGIWDGEAPRCLFDWCPDPPAVSNASV 482
+ G + + C E + L+G C G IW G+ P C C PP + N
Sbjct: 114 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKH 173
Query: 483 T---VNGHKAGSLASYTCE-----NGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTI 534
T V + +Y+C+ + L G +++ C WS P CK V C P +
Sbjct: 174 TFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVV 233
Query: 535 HKGSFVLINGTTTY-GSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSC 583
G + G Y + F C+ ++L+G++ +VC+ + W +P C
Sbjct: 234 ENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 91.5 bits (217), Expect = 2e-17
Identities = 53/173 (30%), Positives = 76/173 (43%), Gaps = 11/173 (6%)
Query: 742 TYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTCQYVDCGNPGRIENGKVTL 798
TY G + + C +GY +IGE + CE G WSG P C+ V C P +I+NGK T
Sbjct: 116 TYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTF 175
Query: 799 PSNATF-YGATAFYQCD-----ENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQI 852
F Y Y CD + + L G C +N WS P CK + C P +
Sbjct: 176 SEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPV--V 233
Query: 853 KAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPI 905
+ G + ++C++G+ L G T C S W+ VP C+ +
Sbjct: 234 ENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKV 286
Score = 84.2 bits (199), Expect = 2e-15
Identities = 60/229 (26%), Positives = 91/229 (39%), Gaps = 21/229 (9%)
Query: 432 GARALYSCRENFTLVGN--PERTCGDEGIW-DGEAPRCLFDWCP---DPPAVSNASVTVN 485
G R Y C++ + + C W C + CP DP ++ +V N
Sbjct: 57 GERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDP--LNGQAVPAN 114
Query: 486 G-HKAGSLASYTCENGHILSGSTSVTCTLGGA---WSGVPPSCKYVNCGTPT-IHKGSFV 540
G ++ G + C G+ L G + C L G+ WSG PP C+ V C P I G
Sbjct: 115 GTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHT 174
Query: 541 LINGTT-TYGSIAQFTCEP-----DYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVP 594
Y ++C+P + L G + C + WS P C++ C P V
Sbjct: 175 FSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVE 234
Query: 595 SGGYMEAFD--YYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTC 641
+G + F +Y +T+ F C+ G L G +VC + W P C
Sbjct: 235 NGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 81.0 bits (191), Expect = 2e-14
Identities = 62/233 (26%), Positives = 96/233 (41%), Gaps = 16/233 (6%)
Query: 743 YRIGALVKYRCEKGYKVIG--ESLSTCEDNGQWSGTT-PTCQYVDCGNPGRIENGKVTLP 799
Y IG V Y+C+KGY I + + C+ N W + C C NG+ +P
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQ-AVP 112
Query: 800 SNATF-YGATAFYQCDENWELEGVIRRMCQENGT---WSLEPPICKEITCPDPSAQIKAG 855
+N T+ +G + C+E + L G C+ G+ WS +PPIC+++ C P +IK G
Sbjct: 113 ANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLC-TPPPKIKNG 171
Query: 856 SGLLVVTSTLSIGGEAHYQCERG-----YNLKGHQTRTCISKGQWNGTVPVCIPIDCRSP 910
Y C+ ++L G T C W+ P C + CR P
Sbjct: 172 KHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFP 231
Query: 911 GNIENGKIVISNGSTL-FGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
+ENGK + G + ++V + C + G C + W P C
Sbjct: 232 -VVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 79.8 bits (188), Expect = 5e-14
Identities = 63/255 (24%), Positives = 102/255 (40%), Gaps = 31/255 (12%)
Query: 604 YYVHSTINFHCEAGHKLIGE--PNLVCQQDGEWSGDSPTCEYID-CGKLPTLPYGTMELL 660
Y + +++ C+ G+ I + +C ++ W S Y + C + G
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA 113
Query: 661 NGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQ---WSDSSPRCEEIRCSDPIVAEKSIV 717
NGT G + + C Y L+G C + WS P CE++ C+ P +
Sbjct: 114 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNG-- 171
Query: 718 SVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKG-----YKVIGESLSTCEDNGQ 772
H + + + D V Y C+ + +IGES C DN
Sbjct: 172 -------KHTFSEVEVFEYLDA---------VTYSCDPAPGPDPFSLIGESTIYCGDNSV 215
Query: 773 WSGTTPTCQYVDCGNPGRIENGK-VTLPSNATFYGATAFYQCDENWELEGVIRRMCQENG 831
WS P C+ V C P +ENGK ++ +Y AT ++CD+ + L+G +C N
Sbjct: 216 WSRAAPECKVVKCRFPV-VENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNS 274
Query: 832 TWSLEPPICKEITCP 846
TW P C ++ P
Sbjct: 275 TWDPPVPKCLKVLPP 289
Score = 78.2 bits (184), Expect = 1e-13
Identities = 65/259 (25%), Positives = 99/259 (38%), Gaps = 28/259 (10%)
Query: 469 DWCPDPPAVSNASVTVNG---HKAGSLASYTCENGH--ILSGSTSVTCTLGGAWSGVPP- 522
D C +PP + ++ G Y C+ G+ I +T C W V
Sbjct: 33 DACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDD 92
Query: 523 SCKYVNCGTPTIH---KGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGK---W 576
+C C P I G V NGT +G F C Y+L G E L C G W
Sbjct: 93 ACYRETC--PYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIW 150
Query: 577 SYDIPSCELTSC-PEPEVPSGGY----MEAFDYYVHSTINFHCEAG-----HKLIGEPNL 626
S P CE C P P++ +G + +E F+Y + + C+ LIGE +
Sbjct: 151 SGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYL--DAVTYSCDPAPGPDPFSLIGESTI 208
Query: 627 VCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTT-HLGSVIQYSCTTNYRLVGPVR 685
C + WS +P C+ + C + P + G G + + + + C + L G
Sbjct: 209 YCGDNSVWSRAAPECKVVKC-RFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDT 267
Query: 686 RTCTEEFQWSDSSPRCEEI 704
C W P+C ++
Sbjct: 268 IVCDSNSTWDPPVPKCLKV 286
Score = 76.2 bits (179), Expect = 6e-13
Identities = 66/252 (26%), Positives = 100/252 (39%), Gaps = 45/252 (17%)
Query: 549 GSIAQFTCEPDYWLNG--AEELVCNRDGKW-SYDIPSCELTSCP---EP----EVPSGGY 598
G + C+ Y+ A +C+R+ W +C +CP +P VP+ G
Sbjct: 57 GERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGT 116
Query: 599 MEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGE---WSGDSPTCEYIDCGKLPTLPYG 655
E F Y +H F C G+ LIGE L C+ G WSG P CE + C P + G
Sbjct: 117 YE-FGYQMH----FICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNG 171
Query: 656 --TMELLNGTTHLGSVIQYSCTTN-----YRLVGPVRRTCTEEFQWSDSSPRCEEIRCSD 708
T + +L +V YSC + L+G C + WS ++P C+ ++C
Sbjct: 172 KHTFSEVEVFEYLDAVT-YSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRF 230
Query: 709 PIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCE 768
P+V +S G + A V + C+KG+ + G C+
Sbjct: 231 PVVENGKQIS-------------------GFGKKFYYKATVMFECDKGFYLDGSDTIVCD 271
Query: 769 DNGQWSGTTPTC 780
N W P C
Sbjct: 272 SNSTWDPPVPKC 283
Score = 60.9 bits (141), Expect = 2e-08
Identities = 40/149 (26%), Positives = 59/149 (39%), Gaps = 12/149 (8%)
Query: 826 MCQENGTW-SLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGH 884
+C N TW + C TCP + + + T G + H+ C GY L G
Sbjct: 79 ICDRNHTWLPVSDDACYRETCPYIRDPLNGQA--VPANGTYEFGYQMHFICNEGYYLIGE 136
Query: 885 QTRTCISKGQ---WNGTVPVCIPIDCRSPGNIENGKIVISNGSTL-FGSSVEYYC----- 935
+ C KG W+G P+C + C P I+NGK S + +V Y C
Sbjct: 137 EILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPG 196
Query: 936 LSQYQRVGPFLRKCLDDGRWSGEEPSCEL 964
+ +G C D+ WS P C++
Sbjct: 197 PDPFSLIGESTIYCGDNSVWSRAAPECKV 225
Score = 58.4 bits (135), Expect = 1e-07
Identities = 39/149 (26%), Positives = 66/149 (44%), Gaps = 13/149 (8%)
Query: 353 CGSPDKLLNTTILGNDYDVGS---RIVYKC-----PEGHMLLGDKSRHCKKDGFWSGAPP 404
C P K+ N ++ +V + Y C P+ L+G+ + +C + WS A P
Sbjct: 162 CTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAP 221
Query: 405 SCKYVNCGGLTPIEDG-DVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEA 463
CK V C +E+G ++ + + A ++ C + F L G+ C WD
Sbjct: 222 ECKVVKCR-FPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPV 280
Query: 464 PRCLFDWCPD---PPAVSNASVTVNGHKA 489
P+CL P PPA+S++ T + K+
Sbjct: 281 PKCLKVLPPSSTKPPALSHSVSTSSTTKS 309
>AL035209-6|CAI18809.1| 384|Homo sapiens CD46 molecule, complement
regulatory protein protein.
Length = 384
Score = 95.5 bits (227), Expect = 9e-19
Identities = 56/230 (24%), Positives = 97/230 (42%), Gaps = 15/230 (6%)
Query: 369 YDVGSRIVYKCPEGHMLLGDKSRH--CKKDGFWSG-APPSCKYVNCGGLTPIEDGDVALI 425
Y++G R+ YKC +G+ + + H C ++ W + +C C + +G
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA 113
Query: 426 DNRTTHGARALYSCRENFTLVGNPERTC---GDEGIWDGEAPRCLFDWCPDPPAVSNASV 482
+ G + + C E + L+G C G IW G+ P C C PP + N
Sbjct: 114 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKH 173
Query: 483 T---VNGHKAGSLASYTCE-----NGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTI 534
T V + +Y+C+ + L G +++ C WS P CK V C P +
Sbjct: 174 TFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVV 233
Query: 535 HKGSFVLINGTTTY-GSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSC 583
G + G Y + F C+ ++L+G++ +VC+ + W +P C
Sbjct: 234 ENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 92.3 bits (219), Expect = 9e-18
Identities = 54/177 (30%), Positives = 77/177 (43%), Gaps = 11/177 (6%)
Query: 742 TYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTCQYVDCGNPGRIENGKVTL 798
TY G + + C +GY +IGE + CE G WSG P C+ V C P +I+NGK T
Sbjct: 116 TYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTF 175
Query: 799 PSNATF-YGATAFYQCD-----ENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQI 852
F Y Y CD + + L G C +N WS P CK + C P +
Sbjct: 176 SEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPV--V 233
Query: 853 KAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRS 909
+ G + ++C++G+ L G T C S W+ VP C+ + S
Sbjct: 234 ENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVSTSS 290
Score = 84.2 bits (199), Expect = 2e-15
Identities = 60/229 (26%), Positives = 91/229 (39%), Gaps = 21/229 (9%)
Query: 432 GARALYSCRENFTLVGN--PERTCGDEGIW-DGEAPRCLFDWCP---DPPAVSNASVTVN 485
G R Y C++ + + C W C + CP DP ++ +V N
Sbjct: 57 GERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDP--LNGQAVPAN 114
Query: 486 G-HKAGSLASYTCENGHILSGSTSVTCTLGGA---WSGVPPSCKYVNCGTPT-IHKGSFV 540
G ++ G + C G+ L G + C L G+ WSG PP C+ V C P I G
Sbjct: 115 GTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHT 174
Query: 541 LINGTT-TYGSIAQFTCEP-----DYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVP 594
Y ++C+P + L G + C + WS P C++ C P V
Sbjct: 175 FSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVE 234
Query: 595 SGGYMEAFD--YYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTC 641
+G + F +Y +T+ F C+ G L G +VC + W P C
Sbjct: 235 NGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 81.4 bits (192), Expect = 2e-14
Identities = 64/244 (26%), Positives = 102/244 (41%), Gaps = 17/244 (6%)
Query: 743 YRIGALVKYRCEKGYKVIG--ESLSTCEDNGQWSGTT-PTCQYVDCGNPGRIENGKVTLP 799
Y IG V Y+C+KGY I + + C+ N W + C C NG+ +P
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQ-AVP 112
Query: 800 SNATF-YGATAFYQCDENWELEGVIRRMCQENGT---WSLEPPICKEITCPDPSAQIKAG 855
+N T+ +G + C+E + L G C+ G+ WS +PPIC+++ C P +IK G
Sbjct: 113 ANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLC-TPPPKIKNG 171
Query: 856 SGLLVVTSTLSIGGEAHYQCERG-----YNLKGHQTRTCISKGQWNGTVPVCIPIDCRSP 910
Y C+ ++L G T C W+ P C + CR P
Sbjct: 172 KHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFP 231
Query: 911 GNIENGKIVISNGSTL-FGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC-ELATNE 968
+ENGK + G + ++V + C + G C + W P C +++T+
Sbjct: 232 -VVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVSTSS 290
Query: 969 AVDS 972
S
Sbjct: 291 TTKS 294
Score = 81.4 bits (192), Expect = 2e-14
Identities = 49/176 (27%), Positives = 78/176 (44%), Gaps = 11/176 (6%)
Query: 369 YDVGSRIVYKCPEGHMLLGDKSRHCKKDG---FWSGAPPSCKYVNCGGLTPIEDGDVALI 425
Y+ G ++ + C EG+ L+G++ +C+ G WSG PP C+ V C I++G
Sbjct: 117 YEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFS 176
Query: 426 DNRTTHGARAL-YSCR-----ENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSN 479
+ A+ YSC + F+L+G CGD +W AP C C P +
Sbjct: 177 EVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVENG 236
Query: 480 ASVTVNGHKAGSLAS--YTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPT 533
++ G K A+ + C+ G L GS ++ C W P C V+ + T
Sbjct: 237 KQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVSTSSTT 292
Score = 79.4 bits (187), Expect = 6e-14
Identities = 68/273 (24%), Positives = 103/273 (37%), Gaps = 28/273 (10%)
Query: 469 DWCPDPPAVSNASVTVNG---HKAGSLASYTCENGH--ILSGSTSVTCTLGGAWSGVPP- 522
D C +PP + ++ G Y C+ G+ I +T C W V
Sbjct: 33 DACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDD 92
Query: 523 SCKYVNCGTPTIH---KGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGK---W 576
+C C P I G V NGT +G F C Y+L G E L C G W
Sbjct: 93 ACYRETC--PYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIW 150
Query: 577 SYDIPSCELTSC-PEPEVPSGGY----MEAFDYYVHSTINFHCEAG-----HKLIGEPNL 626
S P CE C P P++ +G + +E F+Y + + C+ LIGE +
Sbjct: 151 SGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYL--DAVTYSCDPAPGPDPFSLIGESTI 208
Query: 627 VCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTT-HLGSVIQYSCTTNYRLVGPVR 685
C + WS +P C+ + C + P + G G + + + + C + L G
Sbjct: 209 YCGDNSVWSRAAPECKVVKC-RFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDT 267
Query: 686 RTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVS 718
C W P+C ++ S + S S
Sbjct: 268 IVCDSNSTWDPPVPKCLKVSTSSTTKSPASSAS 300
Score = 76.2 bits (179), Expect = 6e-13
Identities = 66/252 (26%), Positives = 100/252 (39%), Gaps = 45/252 (17%)
Query: 549 GSIAQFTCEPDYWLNG--AEELVCNRDGKW-SYDIPSCELTSCP---EP----EVPSGGY 598
G + C+ Y+ A +C+R+ W +C +CP +P VP+ G
Sbjct: 57 GERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGT 116
Query: 599 MEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGE---WSGDSPTCEYIDCGKLPTLPYG 655
E F Y +H F C G+ LIGE L C+ G WSG P CE + C P + G
Sbjct: 117 YE-FGYQMH----FICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNG 171
Query: 656 --TMELLNGTTHLGSVIQYSCTTN-----YRLVGPVRRTCTEEFQWSDSSPRCEEIRCSD 708
T + +L +V YSC + L+G C + WS ++P C+ ++C
Sbjct: 172 KHTFSEVEVFEYLDAVT-YSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRF 230
Query: 709 PIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCE 768
P+V +S G + A V + C+KG+ + G C+
Sbjct: 231 PVVENGKQIS-------------------GFGKKFYYKATVMFECDKGFYLDGSDTIVCD 271
Query: 769 DNGQWSGTTPTC 780
N W P C
Sbjct: 272 SNSTWDPPVPKC 283
Score = 55.2 bits (127), Expect = 1e-06
Identities = 32/124 (25%), Positives = 54/124 (43%), Gaps = 10/124 (8%)
Query: 353 CGSPDKLLNTTILGNDYDVGS---RIVYKC-----PEGHMLLGDKSRHCKKDGFWSGAPP 404
C P K+ N ++ +V + Y C P+ L+G+ + +C + WS A P
Sbjct: 162 CTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAP 221
Query: 405 SCKYVNCGGLTPIEDG-DVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEA 463
CK V C +E+G ++ + + A ++ C + F L G+ C WD
Sbjct: 222 ECKVVKCR-FPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPV 280
Query: 464 PRCL 467
P+CL
Sbjct: 281 PKCL 284
>AL035209-4|CAI18805.1| 392|Homo sapiens CD46 molecule, complement
regulatory protein protein.
Length = 392
Score = 95.5 bits (227), Expect = 9e-19
Identities = 56/230 (24%), Positives = 97/230 (42%), Gaps = 15/230 (6%)
Query: 369 YDVGSRIVYKCPEGHMLLGDKSRH--CKKDGFWSG-APPSCKYVNCGGLTPIEDGDVALI 425
Y++G R+ YKC +G+ + + H C ++ W + +C C + +G
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA 113
Query: 426 DNRTTHGARALYSCRENFTLVGNPERTC---GDEGIWDGEAPRCLFDWCPDPPAVSNASV 482
+ G + + C E + L+G C G IW G+ P C C PP + N
Sbjct: 114 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKH 173
Query: 483 T---VNGHKAGSLASYTCE-----NGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTI 534
T V + +Y+C+ + L G +++ C WS P CK V C P +
Sbjct: 174 TFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVV 233
Query: 535 HKGSFVLINGTTTY-GSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSC 583
G + G Y + F C+ ++L+G++ +VC+ + W +P C
Sbjct: 234 ENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 91.5 bits (217), Expect = 2e-17
Identities = 53/173 (30%), Positives = 76/173 (43%), Gaps = 11/173 (6%)
Query: 742 TYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTCQYVDCGNPGRIENGKVTL 798
TY G + + C +GY +IGE + CE G WSG P C+ V C P +I+NGK T
Sbjct: 116 TYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTF 175
Query: 799 PSNATF-YGATAFYQCD-----ENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQI 852
F Y Y CD + + L G C +N WS P CK + C P +
Sbjct: 176 SEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPV--V 233
Query: 853 KAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPI 905
+ G + ++C++G+ L G T C S W+ VP C+ +
Sbjct: 234 ENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKV 286
Score = 84.2 bits (199), Expect = 2e-15
Identities = 60/229 (26%), Positives = 91/229 (39%), Gaps = 21/229 (9%)
Query: 432 GARALYSCRENFTLVGN--PERTCGDEGIW-DGEAPRCLFDWCP---DPPAVSNASVTVN 485
G R Y C++ + + C W C + CP DP ++ +V N
Sbjct: 57 GERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDP--LNGQAVPAN 114
Query: 486 G-HKAGSLASYTCENGHILSGSTSVTCTLGGA---WSGVPPSCKYVNCGTPT-IHKGSFV 540
G ++ G + C G+ L G + C L G+ WSG PP C+ V C P I G
Sbjct: 115 GTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHT 174
Query: 541 LINGTT-TYGSIAQFTCEP-----DYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVP 594
Y ++C+P + L G + C + WS P C++ C P V
Sbjct: 175 FSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVE 234
Query: 595 SGGYMEAFD--YYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTC 641
+G + F +Y +T+ F C+ G L G +VC + W P C
Sbjct: 235 NGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 81.0 bits (191), Expect = 2e-14
Identities = 62/233 (26%), Positives = 96/233 (41%), Gaps = 16/233 (6%)
Query: 743 YRIGALVKYRCEKGYKVIG--ESLSTCEDNGQWSGTT-PTCQYVDCGNPGRIENGKVTLP 799
Y IG V Y+C+KGY I + + C+ N W + C C NG+ +P
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQ-AVP 112
Query: 800 SNATF-YGATAFYQCDENWELEGVIRRMCQENGT---WSLEPPICKEITCPDPSAQIKAG 855
+N T+ +G + C+E + L G C+ G+ WS +PPIC+++ C P +IK G
Sbjct: 113 ANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLC-TPPPKIKNG 171
Query: 856 SGLLVVTSTLSIGGEAHYQCERG-----YNLKGHQTRTCISKGQWNGTVPVCIPIDCRSP 910
Y C+ ++L G T C W+ P C + CR P
Sbjct: 172 KHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFP 231
Query: 911 GNIENGKIVISNGSTL-FGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
+ENGK + G + ++V + C + G C + W P C
Sbjct: 232 -VVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 79.8 bits (188), Expect = 5e-14
Identities = 63/255 (24%), Positives = 102/255 (40%), Gaps = 31/255 (12%)
Query: 604 YYVHSTINFHCEAGHKLIGE--PNLVCQQDGEWSGDSPTCEYID-CGKLPTLPYGTMELL 660
Y + +++ C+ G+ I + +C ++ W S Y + C + G
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA 113
Query: 661 NGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQ---WSDSSPRCEEIRCSDPIVAEKSIV 717
NGT G + + C Y L+G C + WS P CE++ C+ P +
Sbjct: 114 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNG-- 171
Query: 718 SVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKG-----YKVIGESLSTCEDNGQ 772
H + + + D V Y C+ + +IGES C DN
Sbjct: 172 -------KHTFSEVEVFEYLDA---------VTYSCDPAPGPDPFSLIGESTIYCGDNSV 215
Query: 773 WSGTTPTCQYVDCGNPGRIENGK-VTLPSNATFYGATAFYQCDENWELEGVIRRMCQENG 831
WS P C+ V C P +ENGK ++ +Y AT ++CD+ + L+G +C N
Sbjct: 216 WSRAAPECKVVKCRFPV-VENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNS 274
Query: 832 TWSLEPPICKEITCP 846
TW P C ++ P
Sbjct: 275 TWDPPVPKCLKVLPP 289
Score = 78.2 bits (184), Expect = 1e-13
Identities = 65/259 (25%), Positives = 99/259 (38%), Gaps = 28/259 (10%)
Query: 469 DWCPDPPAVSNASVTVNG---HKAGSLASYTCENGH--ILSGSTSVTCTLGGAWSGVPP- 522
D C +PP + ++ G Y C+ G+ I +T C W V
Sbjct: 33 DACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDD 92
Query: 523 SCKYVNCGTPTIH---KGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGK---W 576
+C C P I G V NGT +G F C Y+L G E L C G W
Sbjct: 93 ACYRETC--PYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIW 150
Query: 577 SYDIPSCELTSC-PEPEVPSGGY----MEAFDYYVHSTINFHCEAG-----HKLIGEPNL 626
S P CE C P P++ +G + +E F+Y + + C+ LIGE +
Sbjct: 151 SGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYL--DAVTYSCDPAPGPDPFSLIGESTI 208
Query: 627 VCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTT-HLGSVIQYSCTTNYRLVGPVR 685
C + WS +P C+ + C + P + G G + + + + C + L G
Sbjct: 209 YCGDNSVWSRAAPECKVVKC-RFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDT 267
Query: 686 RTCTEEFQWSDSSPRCEEI 704
C W P+C ++
Sbjct: 268 IVCDSNSTWDPPVPKCLKV 286
Score = 76.2 bits (179), Expect = 6e-13
Identities = 66/252 (26%), Positives = 100/252 (39%), Gaps = 45/252 (17%)
Query: 549 GSIAQFTCEPDYWLNG--AEELVCNRDGKW-SYDIPSCELTSCP---EP----EVPSGGY 598
G + C+ Y+ A +C+R+ W +C +CP +P VP+ G
Sbjct: 57 GERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGT 116
Query: 599 MEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGE---WSGDSPTCEYIDCGKLPTLPYG 655
E F Y +H F C G+ LIGE L C+ G WSG P CE + C P + G
Sbjct: 117 YE-FGYQMH----FICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNG 171
Query: 656 --TMELLNGTTHLGSVIQYSCTTN-----YRLVGPVRRTCTEEFQWSDSSPRCEEIRCSD 708
T + +L +V YSC + L+G C + WS ++P C+ ++C
Sbjct: 172 KHTFSEVEVFEYLDAVT-YSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRF 230
Query: 709 PIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCE 768
P+V +S G + A V + C+KG+ + G C+
Sbjct: 231 PVVENGKQIS-------------------GFGKKFYYKATVMFECDKGFYLDGSDTIVCD 271
Query: 769 DNGQWSGTTPTC 780
N W P C
Sbjct: 272 SNSTWDPPVPKC 283
Score = 60.9 bits (141), Expect = 2e-08
Identities = 40/149 (26%), Positives = 59/149 (39%), Gaps = 12/149 (8%)
Query: 826 MCQENGTW-SLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGH 884
+C N TW + C TCP + + + T G + H+ C GY L G
Sbjct: 79 ICDRNHTWLPVSDDACYRETCPYIRDPLNGQA--VPANGTYEFGYQMHFICNEGYYLIGE 136
Query: 885 QTRTCISKGQ---WNGTVPVCIPIDCRSPGNIENGKIVISNGSTL-FGSSVEYYC----- 935
+ C KG W+G P+C + C P I+NGK S + +V Y C
Sbjct: 137 EILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPG 196
Query: 936 LSQYQRVGPFLRKCLDDGRWSGEEPSCEL 964
+ +G C D+ WS P C++
Sbjct: 197 PDPFSLIGESTIYCGDNSVWSRAAPECKV 225
Score = 58.4 bits (135), Expect = 1e-07
Identities = 39/149 (26%), Positives = 66/149 (44%), Gaps = 13/149 (8%)
Query: 353 CGSPDKLLNTTILGNDYDVGS---RIVYKC-----PEGHMLLGDKSRHCKKDGFWSGAPP 404
C P K+ N ++ +V + Y C P+ L+G+ + +C + WS A P
Sbjct: 162 CTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAP 221
Query: 405 SCKYVNCGGLTPIEDG-DVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEA 463
CK V C +E+G ++ + + A ++ C + F L G+ C WD
Sbjct: 222 ECKVVKCR-FPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPV 280
Query: 464 PRCLFDWCPD---PPAVSNASVTVNGHKA 489
P+CL P PPA+S++ T + K+
Sbjct: 281 PKCLKVLPPSSTKPPALSHSVSTSSTTKS 309
>AL035209-3|CAI18806.1| 377|Homo sapiens CD46 molecule, complement
regulatory protein protein.
Length = 377
Score = 95.5 bits (227), Expect = 9e-19
Identities = 56/230 (24%), Positives = 97/230 (42%), Gaps = 15/230 (6%)
Query: 369 YDVGSRIVYKCPEGHMLLGDKSRH--CKKDGFWSG-APPSCKYVNCGGLTPIEDGDVALI 425
Y++G R+ YKC +G+ + + H C ++ W + +C C + +G
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA 113
Query: 426 DNRTTHGARALYSCRENFTLVGNPERTC---GDEGIWDGEAPRCLFDWCPDPPAVSNASV 482
+ G + + C E + L+G C G IW G+ P C C PP + N
Sbjct: 114 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKH 173
Query: 483 T---VNGHKAGSLASYTCE-----NGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTI 534
T V + +Y+C+ + L G +++ C WS P CK V C P +
Sbjct: 174 TFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVV 233
Query: 535 HKGSFVLINGTTTY-GSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSC 583
G + G Y + F C+ ++L+G++ +VC+ + W +P C
Sbjct: 234 ENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 92.3 bits (219), Expect = 9e-18
Identities = 54/177 (30%), Positives = 77/177 (43%), Gaps = 11/177 (6%)
Query: 742 TYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTCQYVDCGNPGRIENGKVTL 798
TY G + + C +GY +IGE + CE G WSG P C+ V C P +I+NGK T
Sbjct: 116 TYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTF 175
Query: 799 PSNATF-YGATAFYQCD-----ENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQI 852
F Y Y CD + + L G C +N WS P CK + C P +
Sbjct: 176 SEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPV--V 233
Query: 853 KAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRS 909
+ G + ++C++G+ L G T C S W+ VP C+ + S
Sbjct: 234 ENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVSTSS 290
Score = 84.2 bits (199), Expect = 2e-15
Identities = 60/229 (26%), Positives = 91/229 (39%), Gaps = 21/229 (9%)
Query: 432 GARALYSCRENFTLVGN--PERTCGDEGIW-DGEAPRCLFDWCP---DPPAVSNASVTVN 485
G R Y C++ + + C W C + CP DP ++ +V N
Sbjct: 57 GERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDP--LNGQAVPAN 114
Query: 486 G-HKAGSLASYTCENGHILSGSTSVTCTLGGA---WSGVPPSCKYVNCGTPT-IHKGSFV 540
G ++ G + C G+ L G + C L G+ WSG PP C+ V C P I G
Sbjct: 115 GTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHT 174
Query: 541 LINGTT-TYGSIAQFTCEP-----DYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVP 594
Y ++C+P + L G + C + WS P C++ C P V
Sbjct: 175 FSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVE 234
Query: 595 SGGYMEAFD--YYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTC 641
+G + F +Y +T+ F C+ G L G +VC + W P C
Sbjct: 235 NGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 81.4 bits (192), Expect = 2e-14
Identities = 64/244 (26%), Positives = 102/244 (41%), Gaps = 17/244 (6%)
Query: 743 YRIGALVKYRCEKGYKVIG--ESLSTCEDNGQWSGTT-PTCQYVDCGNPGRIENGKVTLP 799
Y IG V Y+C+KGY I + + C+ N W + C C NG+ +P
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQ-AVP 112
Query: 800 SNATF-YGATAFYQCDENWELEGVIRRMCQENGT---WSLEPPICKEITCPDPSAQIKAG 855
+N T+ +G + C+E + L G C+ G+ WS +PPIC+++ C P +IK G
Sbjct: 113 ANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLC-TPPPKIKNG 171
Query: 856 SGLLVVTSTLSIGGEAHYQCERG-----YNLKGHQTRTCISKGQWNGTVPVCIPIDCRSP 910
Y C+ ++L G T C W+ P C + CR P
Sbjct: 172 KHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFP 231
Query: 911 GNIENGKIVISNGSTL-FGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC-ELATNE 968
+ENGK + G + ++V + C + G C + W P C +++T+
Sbjct: 232 -VVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVSTSS 290
Query: 969 AVDS 972
S
Sbjct: 291 TTKS 294
Score = 81.4 bits (192), Expect = 2e-14
Identities = 49/176 (27%), Positives = 78/176 (44%), Gaps = 11/176 (6%)
Query: 369 YDVGSRIVYKCPEGHMLLGDKSRHCKKDG---FWSGAPPSCKYVNCGGLTPIEDGDVALI 425
Y+ G ++ + C EG+ L+G++ +C+ G WSG PP C+ V C I++G
Sbjct: 117 YEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFS 176
Query: 426 DNRTTHGARAL-YSCR-----ENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSN 479
+ A+ YSC + F+L+G CGD +W AP C C P +
Sbjct: 177 EVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVENG 236
Query: 480 ASVTVNGHKAGSLAS--YTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPT 533
++ G K A+ + C+ G L GS ++ C W P C V+ + T
Sbjct: 237 KQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVSTSSTT 292
Score = 79.4 bits (187), Expect = 6e-14
Identities = 68/273 (24%), Positives = 103/273 (37%), Gaps = 28/273 (10%)
Query: 469 DWCPDPPAVSNASVTVNG---HKAGSLASYTCENGH--ILSGSTSVTCTLGGAWSGVPP- 522
D C +PP + ++ G Y C+ G+ I +T C W V
Sbjct: 33 DACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDD 92
Query: 523 SCKYVNCGTPTIH---KGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGK---W 576
+C C P I G V NGT +G F C Y+L G E L C G W
Sbjct: 93 ACYRETC--PYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIW 150
Query: 577 SYDIPSCELTSC-PEPEVPSGGY----MEAFDYYVHSTINFHCEAG-----HKLIGEPNL 626
S P CE C P P++ +G + +E F+Y + + C+ LIGE +
Sbjct: 151 SGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYL--DAVTYSCDPAPGPDPFSLIGESTI 208
Query: 627 VCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTT-HLGSVIQYSCTTNYRLVGPVR 685
C + WS +P C+ + C + P + G G + + + + C + L G
Sbjct: 209 YCGDNSVWSRAAPECKVVKC-RFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDT 267
Query: 686 RTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVS 718
C W P+C ++ S + S S
Sbjct: 268 IVCDSNSTWDPPVPKCLKVSTSSTTKSPASSAS 300
Score = 76.2 bits (179), Expect = 6e-13
Identities = 66/252 (26%), Positives = 100/252 (39%), Gaps = 45/252 (17%)
Query: 549 GSIAQFTCEPDYWLNG--AEELVCNRDGKW-SYDIPSCELTSCP---EP----EVPSGGY 598
G + C+ Y+ A +C+R+ W +C +CP +P VP+ G
Sbjct: 57 GERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGT 116
Query: 599 MEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGE---WSGDSPTCEYIDCGKLPTLPYG 655
E F Y +H F C G+ LIGE L C+ G WSG P CE + C P + G
Sbjct: 117 YE-FGYQMH----FICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNG 171
Query: 656 --TMELLNGTTHLGSVIQYSCTTN-----YRLVGPVRRTCTEEFQWSDSSPRCEEIRCSD 708
T + +L +V YSC + L+G C + WS ++P C+ ++C
Sbjct: 172 KHTFSEVEVFEYLDAVT-YSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRF 230
Query: 709 PIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCE 768
P+V +S G + A V + C+KG+ + G C+
Sbjct: 231 PVVENGKQIS-------------------GFGKKFYYKATVMFECDKGFYLDGSDTIVCD 271
Query: 769 DNGQWSGTTPTC 780
N W P C
Sbjct: 272 SNSTWDPPVPKC 283
Score = 55.2 bits (127), Expect = 1e-06
Identities = 32/124 (25%), Positives = 54/124 (43%), Gaps = 10/124 (8%)
Query: 353 CGSPDKLLNTTILGNDYDVGS---RIVYKC-----PEGHMLLGDKSRHCKKDGFWSGAPP 404
C P K+ N ++ +V + Y C P+ L+G+ + +C + WS A P
Sbjct: 162 CTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAP 221
Query: 405 SCKYVNCGGLTPIEDG-DVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEA 463
CK V C +E+G ++ + + A ++ C + F L G+ C WD
Sbjct: 222 ECKVVKCR-FPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPV 280
Query: 464 PRCL 467
P+CL
Sbjct: 281 PKCL 284
>AK222822-1|BAD96542.1| 399|Homo sapiens membrane cofactor protein
isoform 2 precursor variant protein.
Length = 399
Score = 95.5 bits (227), Expect = 9e-19
Identities = 56/230 (24%), Positives = 97/230 (42%), Gaps = 15/230 (6%)
Query: 369 YDVGSRIVYKCPEGHMLLGDKSRH--CKKDGFWSG-APPSCKYVNCGGLTPIEDGDVALI 425
Y++G R+ YKC +G+ + + H C ++ W + +C C + +G
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA 113
Query: 426 DNRTTHGARALYSCRENFTLVGNPERTC---GDEGIWDGEAPRCLFDWCPDPPAVSNASV 482
+ G + + C E + L+G C G IW G+ P C C PP + N
Sbjct: 114 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKH 173
Query: 483 T---VNGHKAGSLASYTCE-----NGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTI 534
T V + +Y+C+ + L G +++ C WS P CK V C P +
Sbjct: 174 TFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVV 233
Query: 535 HKGSFVLINGTTTY-GSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSC 583
G + G Y + F C+ ++L+G++ +VC+ + W +P C
Sbjct: 234 ENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 91.5 bits (217), Expect = 2e-17
Identities = 53/173 (30%), Positives = 76/173 (43%), Gaps = 11/173 (6%)
Query: 742 TYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTCQYVDCGNPGRIENGKVTL 798
TY G + + C +GY +IGE + CE G WSG P C+ V C P +I+NGK T
Sbjct: 116 TYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTF 175
Query: 799 PSNATF-YGATAFYQCD-----ENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQI 852
F Y Y CD + + L G C +N WS P CK + C P +
Sbjct: 176 SEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPV--V 233
Query: 853 KAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPI 905
+ G + ++C++G+ L G T C S W+ VP C+ +
Sbjct: 234 ENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKV 286
Score = 84.2 bits (199), Expect = 2e-15
Identities = 60/229 (26%), Positives = 91/229 (39%), Gaps = 21/229 (9%)
Query: 432 GARALYSCRENFTLVGN--PERTCGDEGIW-DGEAPRCLFDWCP---DPPAVSNASVTVN 485
G R Y C++ + + C W C + CP DP ++ +V N
Sbjct: 57 GERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDP--LNGQAVPAN 114
Query: 486 G-HKAGSLASYTCENGHILSGSTSVTCTLGGA---WSGVPPSCKYVNCGTPT-IHKGSFV 540
G ++ G + C G+ L G + C L G+ WSG PP C+ V C P I G
Sbjct: 115 GTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHT 174
Query: 541 LINGTT-TYGSIAQFTCEP-----DYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVP 594
Y ++C+P + L G + C + WS P C++ C P V
Sbjct: 175 FSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVE 234
Query: 595 SGGYMEAFD--YYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTC 641
+G + F +Y +T+ F C+ G L G +VC + W P C
Sbjct: 235 NGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 81.0 bits (191), Expect = 2e-14
Identities = 62/233 (26%), Positives = 96/233 (41%), Gaps = 16/233 (6%)
Query: 743 YRIGALVKYRCEKGYKVIG--ESLSTCEDNGQWSGTT-PTCQYVDCGNPGRIENGKVTLP 799
Y IG V Y+C+KGY I + + C+ N W + C C NG+ +P
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQ-AVP 112
Query: 800 SNATF-YGATAFYQCDENWELEGVIRRMCQENGT---WSLEPPICKEITCPDPSAQIKAG 855
+N T+ +G + C+E + L G C+ G+ WS +PPIC+++ C P +IK G
Sbjct: 113 ANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLC-TPPPKIKNG 171
Query: 856 SGLLVVTSTLSIGGEAHYQCERG-----YNLKGHQTRTCISKGQWNGTVPVCIPIDCRSP 910
Y C+ ++L G T C W+ P C + CR P
Sbjct: 172 KHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFP 231
Query: 911 GNIENGKIVISNGSTL-FGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
+ENGK + G + ++V + C + G C + W P C
Sbjct: 232 -VVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 79.8 bits (188), Expect = 5e-14
Identities = 63/255 (24%), Positives = 102/255 (40%), Gaps = 31/255 (12%)
Query: 604 YYVHSTINFHCEAGHKLIGE--PNLVCQQDGEWSGDSPTCEYID-CGKLPTLPYGTMELL 660
Y + +++ C+ G+ I + +C ++ W S Y + C + G
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA 113
Query: 661 NGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQ---WSDSSPRCEEIRCSDPIVAEKSIV 717
NGT G + + C Y L+G C + WS P CE++ C+ P +
Sbjct: 114 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNG-- 171
Query: 718 SVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKG-----YKVIGESLSTCEDNGQ 772
H + + + D V Y C+ + +IGES C DN
Sbjct: 172 -------KHTFSEVEVFEYLDA---------VTYSCDPAPGPDPFSLIGESTIYCGDNSV 215
Query: 773 WSGTTPTCQYVDCGNPGRIENGK-VTLPSNATFYGATAFYQCDENWELEGVIRRMCQENG 831
WS P C+ V C P +ENGK ++ +Y AT ++CD+ + L+G +C N
Sbjct: 216 WSRAAPECKVVKCRFPV-VENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNS 274
Query: 832 TWSLEPPICKEITCP 846
TW P C ++ P
Sbjct: 275 TWDPPVPKCLKVLPP 289
Score = 78.2 bits (184), Expect = 1e-13
Identities = 65/259 (25%), Positives = 99/259 (38%), Gaps = 28/259 (10%)
Query: 469 DWCPDPPAVSNASVTVNG---HKAGSLASYTCENGH--ILSGSTSVTCTLGGAWSGVPP- 522
D C +PP + ++ G Y C+ G+ I +T C W V
Sbjct: 33 DACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDD 92
Query: 523 SCKYVNCGTPTIH---KGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGK---W 576
+C C P I G V NGT +G F C Y+L G E L C G W
Sbjct: 93 ACYRETC--PYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIW 150
Query: 577 SYDIPSCELTSC-PEPEVPSGGY----MEAFDYYVHSTINFHCEAG-----HKLIGEPNL 626
S P CE C P P++ +G + +E F+Y + + C+ LIGE +
Sbjct: 151 SGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYL--DAVTYSCDPAPGPDPFSLIGESTI 208
Query: 627 VCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTT-HLGSVIQYSCTTNYRLVGPVR 685
C + WS +P C+ + C + P + G G + + + + C + L G
Sbjct: 209 YCGDNSVWSRAAPECKVVKC-RFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDT 267
Query: 686 RTCTEEFQWSDSSPRCEEI 704
C W P+C ++
Sbjct: 268 IVCDSNSTWDPPVPKCLKV 286
Score = 76.2 bits (179), Expect = 6e-13
Identities = 66/252 (26%), Positives = 100/252 (39%), Gaps = 45/252 (17%)
Query: 549 GSIAQFTCEPDYWLNG--AEELVCNRDGKW-SYDIPSCELTSCP---EP----EVPSGGY 598
G + C+ Y+ A +C+R+ W +C +CP +P VP+ G
Sbjct: 57 GERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGT 116
Query: 599 MEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGE---WSGDSPTCEYIDCGKLPTLPYG 655
E F Y +H F C G+ LIGE L C+ G WSG P CE + C P + G
Sbjct: 117 YE-FGYQMH----FICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNG 171
Query: 656 --TMELLNGTTHLGSVIQYSCTTN-----YRLVGPVRRTCTEEFQWSDSSPRCEEIRCSD 708
T + +L +V YSC + L+G C + WS ++P C+ ++C
Sbjct: 172 KHTFSEVEVFEYLDAVT-YSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRF 230
Query: 709 PIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCE 768
P+V +S G + A V + C+KG+ + G C+
Sbjct: 231 PVVENGKQIS-------------------GFGKKFYYKATVMFECDKGFYLDGSDTIVCD 271
Query: 769 DNGQWSGTTPTC 780
N W P C
Sbjct: 272 SNSTWDPPVPKC 283
Score = 60.9 bits (141), Expect = 2e-08
Identities = 40/149 (26%), Positives = 59/149 (39%), Gaps = 12/149 (8%)
Query: 826 MCQENGTW-SLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGH 884
+C N TW + C TCP + + + T G + H+ C GY L G
Sbjct: 79 ICDRNHTWLPVSDDACYRETCPYIRDPLNGQA--VPANGTYEFGYQMHFICNEGYYLIGE 136
Query: 885 QTRTCISKGQ---WNGTVPVCIPIDCRSPGNIENGKIVISNGSTL-FGSSVEYYC----- 935
+ C KG W+G P+C + C P I+NGK S + +V Y C
Sbjct: 137 EILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPG 196
Query: 936 LSQYQRVGPFLRKCLDDGRWSGEEPSCEL 964
+ +G C D+ WS P C++
Sbjct: 197 PDPFSLIGESTIYCGDNSVWSRAAPECKV 225
Score = 58.4 bits (135), Expect = 1e-07
Identities = 39/149 (26%), Positives = 66/149 (44%), Gaps = 13/149 (8%)
Query: 353 CGSPDKLLNTTILGNDYDVGS---RIVYKC-----PEGHMLLGDKSRHCKKDGFWSGAPP 404
C P K+ N ++ +V + Y C P+ L+G+ + +C + WS A P
Sbjct: 162 CTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAP 221
Query: 405 SCKYVNCGGLTPIEDG-DVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEA 463
CK V C +E+G ++ + + A ++ C + F L G+ C WD
Sbjct: 222 ECKVVKCR-FPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPV 280
Query: 464 PRCLFDWCPD---PPAVSNASVTVNGHKA 489
P+CL P PPA+S++ T + K+
Sbjct: 281 PKCLKVLPPSSTKPPALSHSVSTSSTTKS 309
>AL049744-2|CAI19673.1| 385|Homo sapiens complement factor H
protein.
Length = 385
Score = 92.3 bits (219), Expect = 9e-18
Identities = 97/373 (26%), Positives = 143/373 (38%), Gaps = 32/373 (8%)
Query: 346 CQYLPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPP- 404
C LPP + ++L + Y G++ +YKC G+ LG+ C+K G W P
Sbjct: 21 CNELPPRRNT--EILTGSWSDQTYPEGTQAIYKCRPGYRSLGNVIMVCRK-GEWVALNPL 77
Query: 405 -SCKYVNCG--GLTPIEDGDVALI-DNRTTHGARALYSCRENFTLVGNPE-RTCGDEGIW 459
C+ CG G TP G L N +G +A+Y+C E + L+G R C +G W
Sbjct: 78 RKCQKRPCGHPGDTPF--GTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYRECDTDG-W 134
Query: 460 DGEAPRCLFDWCPDPPAVSNASVTVN-GHKAGSLASYTCENGHILSGSTSVTCTLGGAWS 518
+ P C C P ++ + ++ +K Y C G+ S CT G W
Sbjct: 135 TNDIPICEEISCKSPDVINGSPISQKIIYKENERFQYKCNMGYEYSERGDAVCTESG-WR 193
Query: 519 GVPPSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYW-LNGAEELVCNRDGKWS 577
+ PSC+ +C P I G + + G + C ++ C G W
Sbjct: 194 PL-PSCEEKSCDNPYIPNGDYSPLRIKHRTGDEITYQCRNGFYPATRGNTAKCTSTG-W- 250
Query: 578 YDIPSCELTSCPEPEVPSGG-YME-----AFDYYVHSTINFHCEAGHKLIGE---PNLVC 628
P C L C P++ GG Y E F V +++C+ + ++ C
Sbjct: 251 IPAPRCTLKPCDYPDIKHGGLYHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDHIHC 310
Query: 629 QQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTC 688
QDG WS P C P L G + G I +C Y L
Sbjct: 311 TQDG-WSPAVPCLR--KC-YFPYLENGYNQNHGRKFVQGKSIDVACHPGYALPKAQTTVT 366
Query: 689 TEEFQWSDSSPRC 701
E WS +PRC
Sbjct: 367 CMENGWS-PTPRC 378
Score = 89.0 bits (211), Expect = 8e-17
Identities = 67/228 (29%), Positives = 89/228 (39%), Gaps = 15/228 (6%)
Query: 742 TYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPT--CQYVDCGNPGRIENGKVTLP 799
TY G Y+C GY+ +G + C G+W P CQ CG+PG G TL
Sbjct: 41 TYPEGTQAIYKCRPGYRSLGNVIMVCR-KGEWVALNPLRKCQKRPCGHPGDTPFGTFTLT 99
Query: 800 SNATF-YGATAFYQCDENWELEGVIR-RMCQENGTWSLEPPICKEITCPDPSAQIKAGSG 857
F YG A Y C+E ++L G I R C +G W+ + PIC+EI+C P +
Sbjct: 100 GGNVFEYGVKAVYTCNEGYQLLGEINYRECDTDG-WTNDIPICEEISCKSPDVINGSPIS 158
Query: 858 LLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGK 917
++ Y+C GY C G W +P C C +P I NG
Sbjct: 159 QKIIYKE---NERFQYKCNMGYEYSERGDAVCTESG-WR-PLPSCEEKSCDNP-YIPNGD 212
Query: 918 IVISNGSTLFGSSVEYYCLSQ-YQRVGPFLRKCLDDGRWSGEEPSCEL 964
G + Y C + Y KC G W P C L
Sbjct: 213 YSPLRIKHRTGDEITYQCRNGFYPATRGNTAKCTSTG-WI-PAPRCTL 258
Score = 78.2 bits (184), Expect = 1e-13
Identities = 95/395 (24%), Positives = 146/395 (36%), Gaps = 52/395 (13%)
Query: 406 CKYVNCGGLTPIEDGDV---ALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGE 462
C +C L P + ++ + D G +A+Y CR + +GN C +G W
Sbjct: 16 CVAEDCNELPPRRNTEILTGSWSDQTYPEGTQAIYKCRPGYRSLGNVIMVCR-KGEWVAL 74
Query: 463 AP--RCLFDWCPDPPAVSNASVTVNGHKA---GSLASYTCENGHILSGSTSV-TCTLGGA 516
P +C C P + T+ G G A YTC G+ L G + C G
Sbjct: 75 NPLRKCQKRPCGHPGDTPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYRECDTDG- 133
Query: 517 WSGVPPSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKW 576
W+ P C+ ++C +P + GS + Q+ C Y + + VC G W
Sbjct: 134 WTNDIPICEEISCKSPDVINGSPISQKIIYKENERFQYKCNMGYEYSERGDAVCTESG-W 192
Query: 577 SYDIPSCELTSCPEPEVPSGGYME-AFDYYVHSTINFHCEAGHKLIGEPNLV-CQQDGEW 634
+PSCE SC P +P+G Y + I + C G N C G W
Sbjct: 193 R-PLPSCEEKSCDNPYIPNGDYSPLRIKHRTGDEITYQCRNGFYPATRGNTAKCTSTG-W 250
Query: 635 SGDSPTCEYIDCGKLPTLPYG-----TMELLNGTTHLGSVIQYSCTTNYRLVGPV---RR 686
+P C C P + +G M +G Y C ++
Sbjct: 251 I-PAPRCTLKPC-DYPDIKHGGLYHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDHI 308
Query: 687 TCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIG 746
CT++ WS + P C +C P + G +++HG ++ G
Sbjct: 309 HCTQD-GWSPAVP-CLR-KCYFPYLE-------NGYNQNHGRKFVQ-------------G 345
Query: 747 ALVKYRCEKGYKV-IGESLSTCEDNGQWSGTTPTC 780
+ C GY + ++ TC +NG WS TP C
Sbjct: 346 KSIDVACHPGYALPKAQTTVTCMENG-WS-PTPRC 378
Score = 74.9 bits (176), Expect = 1e-12
Identities = 90/341 (26%), Positives = 132/341 (38%), Gaps = 57/341 (16%)
Query: 641 CEYIDCGKLPTLPYGTMELLNG-----TTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWS 695
C DC +LP P E+L G T G+ Y C YR +G V C + +W
Sbjct: 16 CVAEDCNELP--PRRNTEILTGSWSDQTYPEGTQAIYKCRPGYRSLGNVIMVCRKG-EWV 72
Query: 696 DSSP--RCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRC 753
+P +C++ C P ++TG GN + G Y C
Sbjct: 73 ALNPLRKCQKRPCGHPGDTPFGTFTLTG------------------GNVFEYGVKAVYTC 114
Query: 754 EKGYKVIGE-SLSTCEDNGQWSGTTPTCQYVDCGNPGRIENG----KVTLPSNATFYGAT 808
+GY+++GE + C+ +G W+ P C+ + C +P I K+ N F
Sbjct: 115 NEGYQLLGEINYRECDTDG-WTNDIPICEEISCKSPDVINGSPISQKIIYKENERFQ--- 170
Query: 809 AFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIG 868
Y+C+ +E +C E+G L P C+E +C +P S L + T G
Sbjct: 171 --YKCNMGYEYSERGDAVCTESGWRPL--PSCEEKSCDNPYIPNGDYSPLRIKHRT---G 223
Query: 869 GEAHYQCERG-YNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLF 927
E YQC G Y T C S G W P C C P +I++G + N +
Sbjct: 224 DEITYQCRNGFYPATRGNTAKCTSTG-WI-PAPRCTLKPCDYP-DIKHGGLYHENMRRPY 280
Query: 928 -----GSSVEYYCLSQYQR-VGPFLR--KCLDDGRWSGEEP 960
G YYC ++ G + C DG WS P
Sbjct: 281 FPVAVGKYYSYYCDEHFETPSGSYWDHIHCTQDG-WSPAVP 320
Score = 45.6 bits (103), Expect = 0.001
Identities = 23/58 (39%), Positives = 28/58 (48%), Gaps = 2/58 (3%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFG-ARQRECTLRGDWTLEPPFC 58
CGHP P ++ G AVY C+EGY+L G REC G WT + P C
Sbjct: 85 CGHPGDTPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGEINYRECDTDG-WTNDIPIC 141
>AL365178-4|CAH73950.1| 336|Homo sapiens CD46 molecule, complement
regulatory protein protein.
Length = 336
Score = 91.5 bits (217), Expect = 2e-17
Identities = 53/173 (30%), Positives = 76/173 (43%), Gaps = 11/173 (6%)
Query: 742 TYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTCQYVDCGNPGRIENGKVTL 798
TY G + + C +GY +IGE + CE G WSG P C+ V C P +I+NGK T
Sbjct: 53 TYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTF 112
Query: 799 PSNATF-YGATAFYQCD-----ENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQI 852
F Y Y CD + + L G C +N WS P CK + C P +
Sbjct: 113 SEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPV--V 170
Query: 853 KAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPI 905
+ G + ++C++G+ L G T C S W+ VP C+ +
Sbjct: 171 ENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKV 223
Score = 81.0 bits (191), Expect = 2e-14
Identities = 53/187 (28%), Positives = 79/187 (42%), Gaps = 18/187 (9%)
Query: 471 CP---DPPAVSNASVTVNG-HKAGSLASYTCENGHILSGSTSVTCTLGGA---WSGVPPS 523
CP DP ++ +V NG ++ G + C G+ L G + C L G+ WSG PP
Sbjct: 36 CPYIRDP--LNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPI 93
Query: 524 CKYVNCGTPT-IHKGSFVLINGTT-TYGSIAQFTCEP-----DYWLNGAEELVCNRDGKW 576
C+ V C P I G Y ++C+P + L G + C + W
Sbjct: 94 CEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVW 153
Query: 577 SYDIPSCELTSCPEPEVPSGGYMEAFD--YYVHSTINFHCEAGHKLIGEPNLVCQQDGEW 634
S P C++ C P V +G + F +Y +T+ F C+ G L G +VC + W
Sbjct: 154 SRAAPECKVVKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTW 213
Query: 635 SGDSPTC 641
P C
Sbjct: 214 DPPVPKC 220
Score = 79.4 bits (187), Expect = 6e-14
Identities = 47/167 (28%), Positives = 74/167 (44%), Gaps = 11/167 (6%)
Query: 369 YDVGSRIVYKCPEGHMLLGDKSRHCKKDG---FWSGAPPSCKYVNCGGLTPIEDGDVALI 425
Y+ G ++ + C EG+ L+G++ +C+ G WSG PP C+ V C I++G
Sbjct: 54 YEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFS 113
Query: 426 DNRTTHGARAL-YSC-----RENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSN 479
+ A+ YSC + F+L+G CGD +W AP C C P +
Sbjct: 114 EVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVENG 173
Query: 480 ASVTVNGHKAGSLAS--YTCENGHILSGSTSVTCTLGGAWSGVPPSC 524
++ G K A+ + C+ G L GS ++ C W P C
Sbjct: 174 KQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKC 220
Score = 77.0 bits (181), Expect = 3e-13
Identities = 43/164 (26%), Positives = 70/164 (42%), Gaps = 12/164 (7%)
Query: 432 GARALYSCRENFTLVGNPERTC---GDEGIWDGEAPRCLFDWCPDPPAVSNASVT---VN 485
G + + C E + L+G C G IW G+ P C C PP + N T V
Sbjct: 57 GYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVE 116
Query: 486 GHKAGSLASYTCE-----NGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTIHKGSFV 540
+ +Y+C+ + L G +++ C WS P CK V C P + G +
Sbjct: 117 VFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVENGKQI 176
Query: 541 LINGTTTY-GSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSC 583
G Y + F C+ ++L+G++ +VC+ + W +P C
Sbjct: 177 SGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKC 220
Score = 74.5 bits (175), Expect = 2e-12
Identities = 53/195 (27%), Positives = 80/195 (41%), Gaps = 28/195 (14%)
Query: 661 NGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQ---WSDSSPRCEEIRCSDPIVAEKSIV 717
NGT G + + C Y L+G C + WS P CE++ C+ P +
Sbjct: 51 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNG-- 108
Query: 718 SVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKG-----YKVIGESLSTCEDNGQ 772
H + + + D V Y C+ + +IGES C DN
Sbjct: 109 -------KHTFSEVEVFEYLDA---------VTYSCDPAPGPDPFSLIGESTIYCGDNSV 152
Query: 773 WSGTTPTCQYVDCGNPGRIENGK-VTLPSNATFYGATAFYQCDENWELEGVIRRMCQENG 831
WS P C+ V C P +ENGK ++ +Y AT ++CD+ + L+G +C N
Sbjct: 153 WSRAAPECKVVKCRFPV-VENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNS 211
Query: 832 TWSLEPPICKEITCP 846
TW P C ++ P
Sbjct: 212 TWDPPVPKCLKVLPP 226
Score = 71.7 bits (168), Expect = 1e-11
Identities = 48/182 (26%), Positives = 74/182 (40%), Gaps = 17/182 (9%)
Query: 537 GSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGK---WSYDIPSCELTSC-PEPE 592
G V NGT +G F C Y+L G E L C G WS P CE C P P+
Sbjct: 45 GQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPK 104
Query: 593 VPSGGY----MEAFDYYVHSTINFHCEAG-----HKLIGEPNLVCQQDGEWSGDSPTCEY 643
+ +G + +E F+Y + + C+ LIGE + C + WS +P C+
Sbjct: 105 IKNGKHTFSEVEVFEYL--DAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKV 162
Query: 644 IDCGKLPTLPYGTMELLNGTT-HLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCE 702
+ C + P + G G + + + + C + L G C W P+C
Sbjct: 163 VKC-RFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCL 221
Query: 703 EI 704
++
Sbjct: 222 KV 223
Score = 71.3 bits (167), Expect = 2e-11
Identities = 55/198 (27%), Positives = 80/198 (40%), Gaps = 35/198 (17%)
Query: 593 VPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGE---WSGDSPTCEYIDCGKL 649
VP+ G E F Y +H F C G+ LIGE L C+ G WSG P CE + C
Sbjct: 48 VPANGTYE-FGYQMH----FICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPP 102
Query: 650 PTLPYG--TMELLNGTTHLGSVIQYSCTTN-----YRLVGPVRRTCTEEFQWSDSSPRCE 702
P + G T + +L +V YSC + L+G C + WS ++P C+
Sbjct: 103 PKIKNGKHTFSEVEVFEYLDAVT-YSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECK 161
Query: 703 EIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGE 762
++C P+V +S G + A V + C+KG+ + G
Sbjct: 162 VVKCRFPVVENGKQIS-------------------GFGKKFYYKATVMFECDKGFYLDGS 202
Query: 763 SLSTCEDNGQWSGTTPTC 780
C+ N W P C
Sbjct: 203 DTIVCDSNSTWDPPVPKC 220
Score = 65.3 bits (152), Expect = 1e-09
Identities = 47/180 (26%), Positives = 75/180 (41%), Gaps = 13/180 (7%)
Query: 793 NGKVTLPSNATF-YGATAFYQCDENWELEGVIRRMCQENGT---WSLEPPICKEITCPDP 848
NG+ +P+N T+ +G + C+E + L G C+ G+ WS +PPIC+++ C P
Sbjct: 44 NGQA-VPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPP 102
Query: 849 SAQIKAGSGLLVVTSTLSIGGEAHYQCERG-----YNLKGHQTRTCISKGQWNGTVPVCI 903
+IK G Y C+ ++L G T C W+ P C
Sbjct: 103 P-KIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECK 161
Query: 904 PIDCRSPGNIENGKIVISNGSTL-FGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
+ CR P +ENGK + G + ++V + C + G C + W P C
Sbjct: 162 VVKCRFP-VVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKC 220
Score = 58.4 bits (135), Expect = 1e-07
Identities = 39/149 (26%), Positives = 66/149 (44%), Gaps = 13/149 (8%)
Query: 353 CGSPDKLLNTTILGNDYDVGS---RIVYKC-----PEGHMLLGDKSRHCKKDGFWSGAPP 404
C P K+ N ++ +V + Y C P+ L+G+ + +C + WS A P
Sbjct: 99 CTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAP 158
Query: 405 SCKYVNCGGLTPIEDG-DVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEA 463
CK V C +E+G ++ + + A ++ C + F L G+ C WD
Sbjct: 159 ECKVVKC-RFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPV 217
Query: 464 PRCLFDWCPD---PPAVSNASVTVNGHKA 489
P+CL P PPA+S++ T + K+
Sbjct: 218 PKCLKVLPPSSTKPPALSHSVSTSSTTKS 246
Score = 53.6 bits (123), Expect = 4e-06
Identities = 32/110 (29%), Positives = 46/110 (41%), Gaps = 9/110 (8%)
Query: 864 TLSIGGEAHYQCERGYNLKGHQTRTCISKGQ---WNGTVPVCIPIDCRSPGNIENGKIVI 920
T G + H+ C GY L G + C KG W+G P+C + C P I+NGK
Sbjct: 53 TYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTF 112
Query: 921 SNGSTL-FGSSVEYYC-----LSQYQRVGPFLRKCLDDGRWSGEEPSCEL 964
S + +V Y C + +G C D+ WS P C++
Sbjct: 113 SEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKV 162
Score = 35.1 bits (77), Expect = 1.4
Identities = 18/52 (34%), Positives = 26/52 (50%), Gaps = 3/52 (5%)
Query: 915 NGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGR---WSGEEPSCE 963
NG+ V +NG+ FG + + C Y +G + C G WSG+ P CE
Sbjct: 44 NGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICE 95
>AL035209-5|CAI18807.1| 336|Homo sapiens CD46 molecule, complement
regulatory protein protein.
Length = 336
Score = 91.5 bits (217), Expect = 2e-17
Identities = 53/173 (30%), Positives = 76/173 (43%), Gaps = 11/173 (6%)
Query: 742 TYRIGALVKYRCEKGYKVIGESLSTCEDNGQ---WSGTTPTCQYVDCGNPGRIENGKVTL 798
TY G + + C +GY +IGE + CE G WSG P C+ V C P +I+NGK T
Sbjct: 53 TYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTF 112
Query: 799 PSNATF-YGATAFYQCD-----ENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQI 852
F Y Y CD + + L G C +N WS P CK + C P +
Sbjct: 113 SEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPV--V 170
Query: 853 KAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPI 905
+ G + ++C++G+ L G T C S W+ VP C+ +
Sbjct: 171 ENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKV 223
Score = 81.0 bits (191), Expect = 2e-14
Identities = 53/187 (28%), Positives = 79/187 (42%), Gaps = 18/187 (9%)
Query: 471 CP---DPPAVSNASVTVNG-HKAGSLASYTCENGHILSGSTSVTCTLGGA---WSGVPPS 523
CP DP ++ +V NG ++ G + C G+ L G + C L G+ WSG PP
Sbjct: 36 CPYIRDP--LNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPI 93
Query: 524 CKYVNCGTPT-IHKGSFVLINGTT-TYGSIAQFTCEP-----DYWLNGAEELVCNRDGKW 576
C+ V C P I G Y ++C+P + L G + C + W
Sbjct: 94 CEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVW 153
Query: 577 SYDIPSCELTSCPEPEVPSGGYMEAFD--YYVHSTINFHCEAGHKLIGEPNLVCQQDGEW 634
S P C++ C P V +G + F +Y +T+ F C+ G L G +VC + W
Sbjct: 154 SRAAPECKVVKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTW 213
Query: 635 SGDSPTC 641
P C
Sbjct: 214 DPPVPKC 220
Score = 79.4 bits (187), Expect = 6e-14
Identities = 47/167 (28%), Positives = 74/167 (44%), Gaps = 11/167 (6%)
Query: 369 YDVGSRIVYKCPEGHMLLGDKSRHCKKDG---FWSGAPPSCKYVNCGGLTPIEDGDVALI 425
Y+ G ++ + C EG+ L+G++ +C+ G WSG PP C+ V C I++G
Sbjct: 54 YEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFS 113
Query: 426 DNRTTHGARAL-YSC-----RENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSN 479
+ A+ YSC + F+L+G CGD +W AP C C P +
Sbjct: 114 EVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVENG 173
Query: 480 ASVTVNGHKAGSLAS--YTCENGHILSGSTSVTCTLGGAWSGVPPSC 524
++ G K A+ + C+ G L GS ++ C W P C
Sbjct: 174 KQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKC 220
Score = 77.0 bits (181), Expect = 3e-13
Identities = 43/164 (26%), Positives = 70/164 (42%), Gaps = 12/164 (7%)
Query: 432 GARALYSCRENFTLVGNPERTC---GDEGIWDGEAPRCLFDWCPDPPAVSNASVT---VN 485
G + + C E + L+G C G IW G+ P C C PP + N T V
Sbjct: 57 GYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVE 116
Query: 486 GHKAGSLASYTCE-----NGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTIHKGSFV 540
+ +Y+C+ + L G +++ C WS P CK V C P + G +
Sbjct: 117 VFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVENGKQI 176
Query: 541 LINGTTTY-GSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSC 583
G Y + F C+ ++L+G++ +VC+ + W +P C
Sbjct: 177 SGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKC 220
Score = 74.5 bits (175), Expect = 2e-12
Identities = 53/195 (27%), Positives = 80/195 (41%), Gaps = 28/195 (14%)
Query: 661 NGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQ---WSDSSPRCEEIRCSDPIVAEKSIV 717
NGT G + + C Y L+G C + WS P CE++ C+ P +
Sbjct: 51 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNG-- 108
Query: 718 SVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKG-----YKVIGESLSTCEDNGQ 772
H + + + D V Y C+ + +IGES C DN
Sbjct: 109 -------KHTFSEVEVFEYLDA---------VTYSCDPAPGPDPFSLIGESTIYCGDNSV 152
Query: 773 WSGTTPTCQYVDCGNPGRIENGK-VTLPSNATFYGATAFYQCDENWELEGVIRRMCQENG 831
WS P C+ V C P +ENGK ++ +Y AT ++CD+ + L+G +C N
Sbjct: 153 WSRAAPECKVVKCRFPV-VENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNS 211
Query: 832 TWSLEPPICKEITCP 846
TW P C ++ P
Sbjct: 212 TWDPPVPKCLKVLPP 226
Score = 71.7 bits (168), Expect = 1e-11
Identities = 48/182 (26%), Positives = 74/182 (40%), Gaps = 17/182 (9%)
Query: 537 GSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGK---WSYDIPSCELTSC-PEPE 592
G V NGT +G F C Y+L G E L C G WS P CE C P P+
Sbjct: 45 GQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPK 104
Query: 593 VPSGGY----MEAFDYYVHSTINFHCEAG-----HKLIGEPNLVCQQDGEWSGDSPTCEY 643
+ +G + +E F+Y + + C+ LIGE + C + WS +P C+
Sbjct: 105 IKNGKHTFSEVEVFEYL--DAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKV 162
Query: 644 IDCGKLPTLPYGTMELLNGTT-HLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCE 702
+ C + P + G G + + + + C + L G C W P+C
Sbjct: 163 VKC-RFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCL 221
Query: 703 EI 704
++
Sbjct: 222 KV 223
Score = 71.3 bits (167), Expect = 2e-11
Identities = 55/198 (27%), Positives = 80/198 (40%), Gaps = 35/198 (17%)
Query: 593 VPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGE---WSGDSPTCEYIDCGKL 649
VP+ G E F Y +H F C G+ LIGE L C+ G WSG P CE + C
Sbjct: 48 VPANGTYE-FGYQMH----FICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPP 102
Query: 650 PTLPYG--TMELLNGTTHLGSVIQYSCTTN-----YRLVGPVRRTCTEEFQWSDSSPRCE 702
P + G T + +L +V YSC + L+G C + WS ++P C+
Sbjct: 103 PKIKNGKHTFSEVEVFEYLDAVT-YSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECK 161
Query: 703 EIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGE 762
++C P+V +S G + A V + C+KG+ + G
Sbjct: 162 VVKCRFPVVENGKQIS-------------------GFGKKFYYKATVMFECDKGFYLDGS 202
Query: 763 SLSTCEDNGQWSGTTPTC 780
C+ N W P C
Sbjct: 203 DTIVCDSNSTWDPPVPKC 220
Score = 65.3 bits (152), Expect = 1e-09
Identities = 47/180 (26%), Positives = 75/180 (41%), Gaps = 13/180 (7%)
Query: 793 NGKVTLPSNATF-YGATAFYQCDENWELEGVIRRMCQENGT---WSLEPPICKEITCPDP 848
NG+ +P+N T+ +G + C+E + L G C+ G+ WS +PPIC+++ C P
Sbjct: 44 NGQA-VPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPP 102
Query: 849 SAQIKAGSGLLVVTSTLSIGGEAHYQCERG-----YNLKGHQTRTCISKGQWNGTVPVCI 903
+IK G Y C+ ++L G T C W+ P C
Sbjct: 103 P-KIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECK 161
Query: 904 PIDCRSPGNIENGKIVISNGSTL-FGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
+ CR P +ENGK + G + ++V + C + G C + W P C
Sbjct: 162 VVKCRFP-VVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKC 220
Score = 58.4 bits (135), Expect = 1e-07
Identities = 39/149 (26%), Positives = 66/149 (44%), Gaps = 13/149 (8%)
Query: 353 CGSPDKLLNTTILGNDYDVGS---RIVYKC-----PEGHMLLGDKSRHCKKDGFWSGAPP 404
C P K+ N ++ +V + Y C P+ L+G+ + +C + WS A P
Sbjct: 99 CTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAP 158
Query: 405 SCKYVNCGGLTPIEDG-DVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEA 463
CK V C +E+G ++ + + A ++ C + F L G+ C WD
Sbjct: 159 ECKVVKC-RFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPV 217
Query: 464 PRCLFDWCPD---PPAVSNASVTVNGHKA 489
P+CL P PPA+S++ T + K+
Sbjct: 218 PKCLKVLPPSSTKPPALSHSVSTSSTTKS 246
Score = 53.6 bits (123), Expect = 4e-06
Identities = 32/110 (29%), Positives = 46/110 (41%), Gaps = 9/110 (8%)
Query: 864 TLSIGGEAHYQCERGYNLKGHQTRTCISKGQ---WNGTVPVCIPIDCRSPGNIENGKIVI 920
T G + H+ C GY L G + C KG W+G P+C + C P I+NGK
Sbjct: 53 TYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTF 112
Query: 921 SNGSTL-FGSSVEYYC-----LSQYQRVGPFLRKCLDDGRWSGEEPSCEL 964
S + +V Y C + +G C D+ WS P C++
Sbjct: 113 SEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKV 162
Score = 35.1 bits (77), Expect = 1.4
Identities = 18/52 (34%), Positives = 26/52 (50%), Gaps = 3/52 (5%)
Query: 915 NGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGR---WSGEEPSCE 963
NG+ V +NG+ FG + + C Y +G + C G WSG+ P CE
Sbjct: 44 NGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICE 95
>AL391688-3|CAI41009.1| 465|Homo sapiens sushi-repeat-containing
protein, X-linked 2 protein.
Length = 465
Score = 89.4 bits (212), Expect = 6e-17
Identities = 69/250 (27%), Positives = 102/250 (40%), Gaps = 9/250 (3%)
Query: 614 CEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYS 673
C+ G +LIG ++ C WSG + C + C LP + GT NG L S YS
Sbjct: 91 CDRGFRLIGRRSVQCLPSRRWSGTA-YCRQMRCHALPFITSGTYTCTNGVL-LDSRCDYS 148
Query: 674 CTTNYRLVGPVRRTCTEEFQWSDSSPRCEEI---RCSDPIVAEKSIVSVTGNDRSH-GHT 729
C++ Y L G R C E+ +WS P C +I + P EK R +
Sbjct: 149 CSSGYHLEGDRSRICMEDGRWSGGEPVCVDIDPPKIRCPHSREKMAEPEKLTARVYWDPP 208
Query: 730 LIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPG 789
L++ S + + G +G VI + N Q C
Sbjct: 209 LVKDSADGTITRVTLRGPEPGSHFPEGEHVIRYTAYDRAYNRASCKFIVKVQVRRCPTLK 268
Query: 790 RIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPS 849
++G +T S YGAT Y CD ++ +G R+CQ + WS PPIC + +
Sbjct: 269 PPQHGYLTCTSAGDNYGATCEYHCDGGYDRQGTPSRVCQSSRQWSGSPPICAPMKI---N 325
Query: 850 AQIKAGSGLL 859
+ + +GLL
Sbjct: 326 VNVNSAAGLL 335
Score = 71.7 bits (168), Expect = 1e-11
Identities = 35/97 (36%), Positives = 50/97 (51%), Gaps = 2/97 (2%)
Query: 866 SIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGST 925
S+G C+RG+ L G ++ C+ +W+GT C + C + I +G +NG
Sbjct: 82 SLGTRCELSCDRGFRLIGRRSVQCLPSRRWSGTA-YCRQMRCHALPFITSGTYTCTNG-V 139
Query: 926 LFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
L S +Y C S Y G R C++DGRWSG EP C
Sbjct: 140 LLDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVC 176
Score = 66.9 bits (156), Expect = 4e-10
Identities = 60/251 (23%), Positives = 96/251 (38%), Gaps = 22/251 (8%)
Query: 543 NGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPE-PEVPSGGYMEA 601
N ++ G+ + +C+ + L G + C +WS C C P + SG Y
Sbjct: 78 NYHSSLGTRCELSCDRGFRLIGRRSVQCLPSRRWS-GTAYCRQMRCHALPFITSGTYTCT 136
Query: 602 FDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLN 661
+ S ++ C +G+ L G+ + +C +DG WSG P C ID K+ P+ ++
Sbjct: 137 NGVLLDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVDIDPPKI-RCPHSREKMAE 195
Query: 662 GTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEI-----------RCSDPI 710
V G + R + P E + R S
Sbjct: 196 PEKLTARVYWDPPLVKDSADGTITRVTLRGPEPGSHFPEGEHVIRYTAYDRAYNRASCKF 255
Query: 711 VAEKSIVSV-TGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCED 769
+ + + T HG+ L TS G+ Y GA +Y C+ GY G C+
Sbjct: 256 IVKVQVRRCPTLKPPQHGY-LTCTS----AGDNY--GATCEYHCDGGYDRQGTPSRVCQS 308
Query: 770 NGQWSGTTPTC 780
+ QWSG+ P C
Sbjct: 309 SRQWSGSPPIC 319
Score = 62.5 bits (145), Expect = 8e-09
Identities = 31/102 (30%), Positives = 50/102 (49%), Gaps = 2/102 (1%)
Query: 745 IGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATF 804
+G + C++G+++IG C + +WSGT C+ + C I +G T +N
Sbjct: 83 LGTRCELSCDRGFRLIGRRSVQCLPSRRWSGTA-YCRQMRCHALPFITSGTYTC-TNGVL 140
Query: 805 YGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCP 846
+ Y C + LEG R+C E+G WS P+C +I P
Sbjct: 141 LDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVDIDPP 182
Score = 58.4 bits (135), Expect = 1e-07
Identities = 34/121 (28%), Positives = 55/121 (45%), Gaps = 9/121 (7%)
Query: 791 IENGKVTL--PSNATFY---GATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITC 845
I++G+ T P ++ G CD + L G C + WS C+++ C
Sbjct: 64 IQDGEATCYSPKGGNYHSSLGTRCELSCDRGFRLIGRRSVQCLPSRRWS-GTAYCRQMRC 122
Query: 846 PDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPI 905
A SG T+ + + Y C GY+L+G ++R C+ G+W+G PVC+ I
Sbjct: 123 ---HALPFITSGTYTCTNGVLLDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVDI 179
Query: 906 D 906
D
Sbjct: 180 D 180
Score = 57.6 bits (133), Expect = 2e-07
Identities = 64/251 (25%), Positives = 93/251 (37%), Gaps = 40/251 (15%)
Query: 366 GNDY--DVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVA 423
G +Y +G+R C G L+G +S C WSG C+ + C L I G
Sbjct: 76 GGNYHSSLGTRCELSCDRGFRLIGRRSVQCLPSRRWSGTA-YCRQMRCHALPFITSGTYT 134
Query: 424 LIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL-FD----WCP------ 472
N +R YSC + L G+ R C ++G W G P C+ D CP
Sbjct: 135 CT-NGVLLDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVDIDPPKIRCPHSREKM 193
Query: 473 ------------DPPAVSNAS------VTVNGHKAGSLASYTCENGHILSGSTSVTCTLG 514
DPP V +++ VT+ G + G S+ E H++ T+
Sbjct: 194 AEPEKLTARVYWDPPLVKDSADGTITRVTLRGPEPG---SHFPEGEHVIR-YTAYDRAYN 249
Query: 515 GAWSGVPPSCKYVNCGT--PTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNR 572
A + C T P H G + YG+ ++ C+ Y G VC
Sbjct: 250 RASCKFIVKVQVRRCPTLKPPQH-GYLTCTSAGDNYGATCEYHCDGGYDRQGTPSRVCQS 308
Query: 573 DGKWSYDIPSC 583
+WS P C
Sbjct: 309 SRQWSGSPPIC 319
Score = 57.2 bits (132), Expect = 3e-07
Identities = 34/112 (30%), Positives = 47/112 (41%), Gaps = 4/112 (3%)
Query: 485 NGHKA-GSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNC-GTPTIHKGSFVLI 542
N H + G+ +C+ G L G SV C WSG C+ + C P I G++
Sbjct: 78 NYHSSLGTRCELSCDRGFRLIGRRSVQCLPSRRWSGTA-YCRQMRCHALPFITSGTYTCT 136
Query: 543 NGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVP 594
NG S ++C Y L G +C DG+WS P C P+ P
Sbjct: 137 NGVLL-DSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVDIDPPKIRCP 187
Score = 44.8 bits (101), Expect = 0.002
Identities = 19/50 (38%), Positives = 28/50 (56%), Gaps = 1/50 (2%)
Query: 857 GLLVVTSTL-SIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPI 905
G L TS + G Y C+ GY+ +G +R C S QW+G+ P+C P+
Sbjct: 273 GYLTCTSAGDNYGATCEYHCDGGYDRQGTPSRVCQSSRQWSGSPPICAPM 322
Score = 41.9 bits (94), Expect = 0.012
Identities = 47/197 (23%), Positives = 78/197 (39%), Gaps = 20/197 (10%)
Query: 287 PGLTSRTWQWVDGELV-SKPSWGKDQPNNYNGEQNCVVLDGGRGWLWNDVGC-NLDYLHW 344
P +TS T+ +G L+ S+ + + G+++ + ++ GR W + C ++D
Sbjct: 126 PFITSGTYTCTNGVLLDSRCDYSCSSGYHLEGDRSRICMEDGR-WSGGEPVCVDIDPPKI 184
Query: 345 ICQYLPPTCGSPDKLLNTTI----LGNDYDVGS--RIVYKCPE--GHMLLGDKS-RHCKK 395
C + P+KL L D G+ R+ + PE H G+ R+
Sbjct: 185 RCPHSREKMAEPEKLTARVYWDPPLVKDSADGTITRVTLRGPEPGSHFPEGEHVIRYTAY 244
Query: 396 DGFWSGAPPSCKYV------NCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNP 449
D ++ A SCK++ C L P + G + +GA Y C + G P
Sbjct: 245 DRAYNRA--SCKFIVKVQVRRCPTLKPPQHGYLTCTSAGDNYGATCEYHCDGGYDRQGTP 302
Query: 450 ERTCGDEGIWDGEAPRC 466
R C W G P C
Sbjct: 303 SRVCQSSRQWSGSPPIC 319
Score = 38.3 bits (85), Expect = 0.15
Identities = 15/49 (30%), Positives = 25/49 (51%)
Query: 914 ENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
++G + ++ +G++ EY+C Y R G R C +WSG P C
Sbjct: 271 QHGYLTCTSAGDNYGATCEYHCDGGYDRQGTPSRVCQSSRQWSGSPPIC 319
Score = 33.9 bits (74), Expect = 3.2
Identities = 13/35 (37%), Positives = 15/35 (42%)
Query: 24 GTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
G Y CD GY+ G R C W+ PP C
Sbjct: 285 GATCEYHCDGGYDRQGTPSRVCQSSRQWSGSPPIC 319
>AL035608-3|CAI42847.1| 465|Homo sapiens sushi-repeat-containing
protein, X-linked 2 protein.
Length = 465
Score = 89.4 bits (212), Expect = 6e-17
Identities = 69/250 (27%), Positives = 102/250 (40%), Gaps = 9/250 (3%)
Query: 614 CEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYS 673
C+ G +LIG ++ C WSG + C + C LP + GT NG L S YS
Sbjct: 91 CDRGFRLIGRRSVQCLPSRRWSGTA-YCRQMRCHALPFITSGTYTCTNGVL-LDSRCDYS 148
Query: 674 CTTNYRLVGPVRRTCTEEFQWSDSSPRCEEI---RCSDPIVAEKSIVSVTGNDRSH-GHT 729
C++ Y L G R C E+ +WS P C +I + P EK R +
Sbjct: 149 CSSGYHLEGDRSRICMEDGRWSGGEPVCVDIDPPKIRCPHSREKMAEPEKLTARVYWDPP 208
Query: 730 LIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPG 789
L++ S + + G +G VI + N Q C
Sbjct: 209 LVKDSADGTITRVTLRGPEPGSHFPEGEHVIRYTAYDRAYNRASCKFIVKVQVRRCPTLK 268
Query: 790 RIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPS 849
++G +T S YGAT Y CD ++ +G R+CQ + WS PPIC + +
Sbjct: 269 PPQHGYLTCTSAGDNYGATCEYHCDGGYDRQGTPSRVCQSSRQWSGSPPICAPMKI---N 325
Query: 850 AQIKAGSGLL 859
+ + +GLL
Sbjct: 326 VNVNSAAGLL 335
Score = 71.7 bits (168), Expect = 1e-11
Identities = 35/97 (36%), Positives = 50/97 (51%), Gaps = 2/97 (2%)
Query: 866 SIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGST 925
S+G C+RG+ L G ++ C+ +W+GT C + C + I +G +NG
Sbjct: 82 SLGTRCELSCDRGFRLIGRRSVQCLPSRRWSGTA-YCRQMRCHALPFITSGTYTCTNG-V 139
Query: 926 LFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
L S +Y C S Y G R C++DGRWSG EP C
Sbjct: 140 LLDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVC 176
Score = 66.9 bits (156), Expect = 4e-10
Identities = 60/251 (23%), Positives = 96/251 (38%), Gaps = 22/251 (8%)
Query: 543 NGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPE-PEVPSGGYMEA 601
N ++ G+ + +C+ + L G + C +WS C C P + SG Y
Sbjct: 78 NYHSSLGTRCELSCDRGFRLIGRRSVQCLPSRRWS-GTAYCRQMRCHALPFITSGTYTCT 136
Query: 602 FDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLN 661
+ S ++ C +G+ L G+ + +C +DG WSG P C ID K+ P+ ++
Sbjct: 137 NGVLLDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVDIDPPKI-RCPHSREKMAE 195
Query: 662 GTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEI-----------RCSDPI 710
V G + R + P E + R S
Sbjct: 196 PEKLTARVYWDPPLVKDSADGTITRVTLRGPEPGSHFPEGEHVIRYTAYDRAYNRASCKF 255
Query: 711 VAEKSIVSV-TGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCED 769
+ + + T HG+ L TS G+ Y GA +Y C+ GY G C+
Sbjct: 256 IVKVQVRRCPTLKPPQHGY-LTCTS----AGDNY--GATCEYHCDGGYDRQGTPSRVCQS 308
Query: 770 NGQWSGTTPTC 780
+ QWSG+ P C
Sbjct: 309 SRQWSGSPPIC 319
Score = 62.5 bits (145), Expect = 8e-09
Identities = 31/102 (30%), Positives = 50/102 (49%), Gaps = 2/102 (1%)
Query: 745 IGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATF 804
+G + C++G+++IG C + +WSGT C+ + C I +G T +N
Sbjct: 83 LGTRCELSCDRGFRLIGRRSVQCLPSRRWSGTA-YCRQMRCHALPFITSGTYTC-TNGVL 140
Query: 805 YGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCP 846
+ Y C + LEG R+C E+G WS P+C +I P
Sbjct: 141 LDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVDIDPP 182
Score = 58.4 bits (135), Expect = 1e-07
Identities = 34/121 (28%), Positives = 55/121 (45%), Gaps = 9/121 (7%)
Query: 791 IENGKVTL--PSNATFY---GATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITC 845
I++G+ T P ++ G CD + L G C + WS C+++ C
Sbjct: 64 IQDGEATCYSPKGGNYHSSLGTRCELSCDRGFRLIGRRSVQCLPSRRWS-GTAYCRQMRC 122
Query: 846 PDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPI 905
A SG T+ + + Y C GY+L+G ++R C+ G+W+G PVC+ I
Sbjct: 123 ---HALPFITSGTYTCTNGVLLDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVDI 179
Query: 906 D 906
D
Sbjct: 180 D 180
Score = 57.6 bits (133), Expect = 2e-07
Identities = 64/251 (25%), Positives = 93/251 (37%), Gaps = 40/251 (15%)
Query: 366 GNDY--DVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVA 423
G +Y +G+R C G L+G +S C WSG C+ + C L I G
Sbjct: 76 GGNYHSSLGTRCELSCDRGFRLIGRRSVQCLPSRRWSGTA-YCRQMRCHALPFITSGTYT 134
Query: 424 LIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL-FD----WCP------ 472
N +R YSC + L G+ R C ++G W G P C+ D CP
Sbjct: 135 CT-NGVLLDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVDIDPPKIRCPHSREKM 193
Query: 473 ------------DPPAVSNAS------VTVNGHKAGSLASYTCENGHILSGSTSVTCTLG 514
DPP V +++ VT+ G + G S+ E H++ T+
Sbjct: 194 AEPEKLTARVYWDPPLVKDSADGTITRVTLRGPEPG---SHFPEGEHVIR-YTAYDRAYN 249
Query: 515 GAWSGVPPSCKYVNCGT--PTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNR 572
A + C T P H G + YG+ ++ C+ Y G VC
Sbjct: 250 RASCKFIVKVQVRRCPTLKPPQH-GYLTCTSAGDNYGATCEYHCDGGYDRQGTPSRVCQS 308
Query: 573 DGKWSYDIPSC 583
+WS P C
Sbjct: 309 SRQWSGSPPIC 319
Score = 57.2 bits (132), Expect = 3e-07
Identities = 34/112 (30%), Positives = 47/112 (41%), Gaps = 4/112 (3%)
Query: 485 NGHKA-GSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNC-GTPTIHKGSFVLI 542
N H + G+ +C+ G L G SV C WSG C+ + C P I G++
Sbjct: 78 NYHSSLGTRCELSCDRGFRLIGRRSVQCLPSRRWSGTA-YCRQMRCHALPFITSGTYTCT 136
Query: 543 NGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVP 594
NG S ++C Y L G +C DG+WS P C P+ P
Sbjct: 137 NGVLL-DSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVDIDPPKIRCP 187
Score = 44.8 bits (101), Expect = 0.002
Identities = 19/50 (38%), Positives = 28/50 (56%), Gaps = 1/50 (2%)
Query: 857 GLLVVTSTL-SIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPI 905
G L TS + G Y C+ GY+ +G +R C S QW+G+ P+C P+
Sbjct: 273 GYLTCTSAGDNYGATCEYHCDGGYDRQGTPSRVCQSSRQWSGSPPICAPM 322
Score = 41.9 bits (94), Expect = 0.012
Identities = 47/197 (23%), Positives = 78/197 (39%), Gaps = 20/197 (10%)
Query: 287 PGLTSRTWQWVDGELV-SKPSWGKDQPNNYNGEQNCVVLDGGRGWLWNDVGC-NLDYLHW 344
P +TS T+ +G L+ S+ + + G+++ + ++ GR W + C ++D
Sbjct: 126 PFITSGTYTCTNGVLLDSRCDYSCSSGYHLEGDRSRICMEDGR-WSGGEPVCVDIDPPKI 184
Query: 345 ICQYLPPTCGSPDKLLNTTI----LGNDYDVGS--RIVYKCPE--GHMLLGDKS-RHCKK 395
C + P+KL L D G+ R+ + PE H G+ R+
Sbjct: 185 RCPHSREKMAEPEKLTARVYWDPPLVKDSADGTITRVTLRGPEPGSHFPEGEHVIRYTAY 244
Query: 396 DGFWSGAPPSCKYV------NCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNP 449
D ++ A SCK++ C L P + G + +GA Y C + G P
Sbjct: 245 DRAYNRA--SCKFIVKVQVRRCPTLKPPQHGYLTCTSAGDNYGATCEYHCDGGYDRQGTP 302
Query: 450 ERTCGDEGIWDGEAPRC 466
R C W G P C
Sbjct: 303 SRVCQSSRQWSGSPPIC 319
Score = 38.3 bits (85), Expect = 0.15
Identities = 15/49 (30%), Positives = 25/49 (51%)
Query: 914 ENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
++G + ++ +G++ EY+C Y R G R C +WSG P C
Sbjct: 271 QHGYLTCTSAGDNYGATCEYHCDGGYDRQGTPSRVCQSSRQWSGSPPIC 319
Score = 33.9 bits (74), Expect = 3.2
Identities = 13/35 (37%), Positives = 15/35 (42%)
Query: 24 GTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
G Y CD GY+ G R C W+ PP C
Sbjct: 285 GATCEYHCDGGYDRQGTPSRVCQSSRQWSGSPPIC 319
>AF393649-1|AAM73693.1| 465|Homo sapiens sushi-repeat containing
protein protein.
Length = 465
Score = 89.4 bits (212), Expect = 6e-17
Identities = 69/250 (27%), Positives = 102/250 (40%), Gaps = 9/250 (3%)
Query: 614 CEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYS 673
C+ G +LIG ++ C WSG + C + C LP + GT NG L S YS
Sbjct: 91 CDRGFRLIGRRSVQCLPSRRWSGTA-YCRQMRCHALPFITSGTYTCTNGVL-LDSRCDYS 148
Query: 674 CTTNYRLVGPVRRTCTEEFQWSDSSPRCEEI---RCSDPIVAEKSIVSVTGNDRSH-GHT 729
C++ Y L G R C E+ +WS P C +I + P EK R +
Sbjct: 149 CSSGYHLEGDRSRICMEDGRWSGGEPVCVDIDPPKIRCPHSREKMAEPEKLTARVYWDPP 208
Query: 730 LIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPG 789
L++ S + + G +G VI + N Q C
Sbjct: 209 LVKDSADGTITRVTLRGPEPGSHFPEGEHVIRYTAYDRAYNRASCKFIVKVQVRRCPTLK 268
Query: 790 RIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPS 849
++G +T S YGAT Y CD ++ +G R+CQ + WS PPIC + +
Sbjct: 269 PPQHGYLTCTSAGDNYGATCEYHCDGGYDRQGTPSRVCQSSRQWSGSPPICAPMKI---N 325
Query: 850 AQIKAGSGLL 859
+ + +GLL
Sbjct: 326 VNVNSAAGLL 335
Score = 71.7 bits (168), Expect = 1e-11
Identities = 35/97 (36%), Positives = 50/97 (51%), Gaps = 2/97 (2%)
Query: 866 SIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGST 925
S+G C+RG+ L G ++ C+ +W+GT C + C + I +G +NG
Sbjct: 82 SLGTRCELSCDRGFRLIGRRSVQCLPSRRWSGTA-YCRQMRCHALPFITSGTYTCTNG-V 139
Query: 926 LFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
L S +Y C S Y G R C++DGRWSG EP C
Sbjct: 140 LLDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVC 176
Score = 66.9 bits (156), Expect = 4e-10
Identities = 60/251 (23%), Positives = 96/251 (38%), Gaps = 22/251 (8%)
Query: 543 NGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPE-PEVPSGGYMEA 601
N ++ G+ + +C+ + L G + C +WS C C P + SG Y
Sbjct: 78 NYHSSLGTRCELSCDRGFRLIGRRSVQCLPSRRWS-GTAYCRQMRCHALPFITSGTYTCT 136
Query: 602 FDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLN 661
+ S ++ C +G+ L G+ + +C +DG WSG P C ID K+ P+ ++
Sbjct: 137 NGVLLDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVDIDPPKI-RCPHSREKMAE 195
Query: 662 GTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEI-----------RCSDPI 710
V G + R + P E + R S
Sbjct: 196 PEKLTARVYWDPPLVKDSADGTITRVTLRGPEPGSHFPEGEHVIRYTAYDRAYNRASCKF 255
Query: 711 VAEKSIVSV-TGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCED 769
+ + + T HG+ L TS G+ Y GA +Y C+ GY G C+
Sbjct: 256 IVKVQVRRCPTLKPPQHGY-LTCTS----AGDNY--GATCEYHCDGGYDRQGTPSRVCQS 308
Query: 770 NGQWSGTTPTC 780
+ QWSG+ P C
Sbjct: 309 SRQWSGSPPIC 319
Score = 62.5 bits (145), Expect = 8e-09
Identities = 31/102 (30%), Positives = 50/102 (49%), Gaps = 2/102 (1%)
Query: 745 IGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATF 804
+G + C++G+++IG C + +WSGT C+ + C I +G T +N
Sbjct: 83 LGTRCELSCDRGFRLIGRRSVQCLPSRRWSGTA-YCRQMRCHALPFITSGTYTC-TNGVL 140
Query: 805 YGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCP 846
+ Y C + LEG R+C E+G WS P+C +I P
Sbjct: 141 LDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVDIDPP 182
Score = 58.4 bits (135), Expect = 1e-07
Identities = 34/121 (28%), Positives = 55/121 (45%), Gaps = 9/121 (7%)
Query: 791 IENGKVTL--PSNATFY---GATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITC 845
I++G+ T P ++ G CD + L G C + WS C+++ C
Sbjct: 64 IQDGEATCYSPKGGNYHSSLGTRCELSCDRGFRLIGRRSVQCLPSRRWS-GTAYCRQMRC 122
Query: 846 PDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPI 905
A SG T+ + + Y C GY+L+G ++R C+ G+W+G PVC+ I
Sbjct: 123 ---HALPFITSGTYTCTNGVLLDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVDI 179
Query: 906 D 906
D
Sbjct: 180 D 180
Score = 57.6 bits (133), Expect = 2e-07
Identities = 64/251 (25%), Positives = 93/251 (37%), Gaps = 40/251 (15%)
Query: 366 GNDY--DVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVA 423
G +Y +G+R C G L+G +S C WSG C+ + C L I G
Sbjct: 76 GGNYHSSLGTRCELSCDRGFRLIGRRSVQCLPSRRWSGTA-YCRQMRCHALPFITSGTYT 134
Query: 424 LIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL-FD----WCP------ 472
N +R YSC + L G+ R C ++G W G P C+ D CP
Sbjct: 135 CT-NGVLLDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVDIDPPKIRCPHSREKM 193
Query: 473 ------------DPPAVSNAS------VTVNGHKAGSLASYTCENGHILSGSTSVTCTLG 514
DPP V +++ VT+ G + G S+ E H++ T+
Sbjct: 194 AEPEKLTARVYWDPPLVKDSADGTITRVTLRGPEPG---SHFPEGEHVIR-YTAYDRAYN 249
Query: 515 GAWSGVPPSCKYVNCGT--PTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNR 572
A + C T P H G + YG+ ++ C+ Y G VC
Sbjct: 250 RASCKFIVKVQVRRCPTLKPPQH-GYLTCTSAGDNYGATCEYHCDGGYDRQGTPSRVCQS 308
Query: 573 DGKWSYDIPSC 583
+WS P C
Sbjct: 309 SRQWSGSPPIC 319
Score = 57.2 bits (132), Expect = 3e-07
Identities = 34/112 (30%), Positives = 47/112 (41%), Gaps = 4/112 (3%)
Query: 485 NGHKA-GSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNC-GTPTIHKGSFVLI 542
N H + G+ +C+ G L G SV C WSG C+ + C P I G++
Sbjct: 78 NYHSSLGTRCELSCDRGFRLIGRRSVQCLPSRRWSGTA-YCRQMRCHALPFITSGTYTCT 136
Query: 543 NGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVP 594
NG S ++C Y L G +C DG+WS P C P+ P
Sbjct: 137 NGVLL-DSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVDIDPPKIRCP 187
Score = 44.8 bits (101), Expect = 0.002
Identities = 19/50 (38%), Positives = 28/50 (56%), Gaps = 1/50 (2%)
Query: 857 GLLVVTSTL-SIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPI 905
G L TS + G Y C+ GY+ +G +R C S QW+G+ P+C P+
Sbjct: 273 GYLTCTSAGDNYGATCEYHCDGGYDRQGTPSRVCQSSRQWSGSPPICAPM 322
Score = 41.9 bits (94), Expect = 0.012
Identities = 47/197 (23%), Positives = 78/197 (39%), Gaps = 20/197 (10%)
Query: 287 PGLTSRTWQWVDGELV-SKPSWGKDQPNNYNGEQNCVVLDGGRGWLWNDVGC-NLDYLHW 344
P +TS T+ +G L+ S+ + + G+++ + ++ GR W + C ++D
Sbjct: 126 PFITSGTYTCTNGVLLDSRCDYSCSSGYHLEGDRSRICMEDGR-WSGGEPVCVDIDPPKI 184
Query: 345 ICQYLPPTCGSPDKLLNTTI----LGNDYDVGS--RIVYKCPE--GHMLLGDKS-RHCKK 395
C + P+KL L D G+ R+ + PE H G+ R+
Sbjct: 185 RCPHSREKMAEPEKLTARVYWDPPLVKDSADGTITRVTLRGPEPGSHFPEGEHVIRYTAY 244
Query: 396 DGFWSGAPPSCKYV------NCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNP 449
D ++ A SCK++ C L P + G + +GA Y C + G P
Sbjct: 245 DRAYNRA--SCKFIVKVQVRRCPTLKPPQHGYLTCTSAGDNYGATCEYHCDGGYDRQGTP 302
Query: 450 ERTCGDEGIWDGEAPRC 466
R C W G P C
Sbjct: 303 SRVCQSSRQWSGSPPIC 319
Score = 38.3 bits (85), Expect = 0.15
Identities = 15/49 (30%), Positives = 25/49 (51%)
Query: 914 ENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
++G + ++ +G++ EY+C Y R G R C +WSG P C
Sbjct: 271 QHGYLTCTSAGDNYGATCEYHCDGGYDRQGTPSRVCQSSRQWSGSPPIC 319
Score = 33.9 bits (74), Expect = 3.2
Identities = 13/35 (37%), Positives = 15/35 (42%)
Query: 24 GTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
G Y CD GY+ G R C W+ PP C
Sbjct: 285 GATCEYHCDGGYDRQGTPSRVCQSSRQWSGSPPIC 319
>AF060567-1|AAC15765.1| 465|Homo sapiens sushi-repeat protein
protein.
Length = 465
Score = 89.4 bits (212), Expect = 6e-17
Identities = 69/250 (27%), Positives = 102/250 (40%), Gaps = 9/250 (3%)
Query: 614 CEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYS 673
C+ G +LIG ++ C WSG + C + C LP + GT NG L S YS
Sbjct: 91 CDRGFRLIGRRSVQCLPSRRWSGTA-YCRQMRCHALPFITSGTYTCTNGVL-LDSRCDYS 148
Query: 674 CTTNYRLVGPVRRTCTEEFQWSDSSPRCEEI---RCSDPIVAEKSIVSVTGNDRSH-GHT 729
C++ Y L G R C E+ +WS P C +I + P EK R +
Sbjct: 149 CSSGYHLEGDRSRICMEDGRWSGGEPVCVDIDPPKIRCPHSREKMAEPEKLTARVYWDPP 208
Query: 730 LIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPG 789
L++ S + + G +G VI + N Q C
Sbjct: 209 LVKDSADGTITRVTLRGPEPGSHFPEGEHVIRYTAYDRAYNRASCKFIVKVQVRRCPTLK 268
Query: 790 RIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPS 849
++G +T S YGAT Y CD ++ +G R+CQ + WS PPIC + +
Sbjct: 269 PPQHGYLTCTSAGDNYGATCEYHCDGGYDRQGTPSRVCQSSRQWSGSPPICAPMKI---N 325
Query: 850 AQIKAGSGLL 859
+ + +GLL
Sbjct: 326 VNVNSAAGLL 335
Score = 71.7 bits (168), Expect = 1e-11
Identities = 35/97 (36%), Positives = 50/97 (51%), Gaps = 2/97 (2%)
Query: 866 SIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGST 925
S+G C+RG+ L G ++ C+ +W+GT C + C + I +G +NG
Sbjct: 82 SLGTRCELSCDRGFRLIGRRSVQCLPSRRWSGTA-YCRQMRCHALPFITSGTYTCTNG-V 139
Query: 926 LFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
L S +Y C S Y G R C++DGRWSG EP C
Sbjct: 140 LLDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVC 176
Score = 66.9 bits (156), Expect = 4e-10
Identities = 60/251 (23%), Positives = 96/251 (38%), Gaps = 22/251 (8%)
Query: 543 NGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPE-PEVPSGGYMEA 601
N ++ G+ + +C+ + L G + C +WS C C P + SG Y
Sbjct: 78 NYHSSLGTRCELSCDRGFRLIGRRSVQCLPSRRWS-GTAYCRQMRCHALPFITSGTYTCT 136
Query: 602 FDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLN 661
+ S ++ C +G+ L G+ + +C +DG WSG P C ID K+ P+ ++
Sbjct: 137 NGVLLDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVDIDPPKI-RCPHSREKMAE 195
Query: 662 GTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEI-----------RCSDPI 710
V G + R + P E + R S
Sbjct: 196 PEKLTARVYWDPPLVKDSADGTITRVTLRGPEPGSHFPEGEHVIRYTAYDRAYNRASCKF 255
Query: 711 VAEKSIVSV-TGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCED 769
+ + + T HG+ L TS G+ Y GA +Y C+ GY G C+
Sbjct: 256 IVKVQVRRCPTLKPPQHGY-LTCTS----AGDNY--GATCEYHCDGGYDRQGTPSRVCQS 308
Query: 770 NGQWSGTTPTC 780
+ QWSG+ P C
Sbjct: 309 SRQWSGSPPIC 319
Score = 62.5 bits (145), Expect = 8e-09
Identities = 31/102 (30%), Positives = 50/102 (49%), Gaps = 2/102 (1%)
Query: 745 IGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATF 804
+G + C++G+++IG C + +WSGT C+ + C I +G T +N
Sbjct: 83 LGTRCELSCDRGFRLIGRRSVQCLPSRRWSGTA-YCRQMRCHALPFITSGTYTC-TNGVL 140
Query: 805 YGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCP 846
+ Y C + LEG R+C E+G WS P+C +I P
Sbjct: 141 LDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVDIDPP 182
Score = 58.4 bits (135), Expect = 1e-07
Identities = 34/121 (28%), Positives = 55/121 (45%), Gaps = 9/121 (7%)
Query: 791 IENGKVTL--PSNATFY---GATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITC 845
I++G+ T P ++ G CD + L G C + WS C+++ C
Sbjct: 64 IQDGEATCYSPKGGNYHSSLGTRCELSCDRGFRLIGRRSVQCLPSRRWS-GTAYCRQMRC 122
Query: 846 PDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPI 905
A SG T+ + + Y C GY+L+G ++R C+ G+W+G PVC+ I
Sbjct: 123 ---HALPFITSGTYTCTNGVLLDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVDI 179
Query: 906 D 906
D
Sbjct: 180 D 180
Score = 57.6 bits (133), Expect = 2e-07
Identities = 64/251 (25%), Positives = 93/251 (37%), Gaps = 40/251 (15%)
Query: 366 GNDY--DVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVA 423
G +Y +G+R C G L+G +S C WSG C+ + C L I G
Sbjct: 76 GGNYHSSLGTRCELSCDRGFRLIGRRSVQCLPSRRWSGTA-YCRQMRCHALPFITSGTYT 134
Query: 424 LIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL-FD----WCP------ 472
N +R YSC + L G+ R C ++G W G P C+ D CP
Sbjct: 135 CT-NGVLLDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVDIDPPKIRCPHSREKM 193
Query: 473 ------------DPPAVSNAS------VTVNGHKAGSLASYTCENGHILSGSTSVTCTLG 514
DPP V +++ VT+ G + G S+ E H++ T+
Sbjct: 194 AEPEKLTARVYWDPPLVKDSADGTITRVTLRGPEPG---SHFPEGEHVIR-YTAYDRAYN 249
Query: 515 GAWSGVPPSCKYVNCGT--PTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNR 572
A + C T P H G + YG+ ++ C+ Y G VC
Sbjct: 250 RASCKFIVKVQVRRCPTLKPPQH-GYLTCTSAGDNYGATCEYHCDGGYDRQGTPSRVCQS 308
Query: 573 DGKWSYDIPSC 583
+WS P C
Sbjct: 309 SRQWSGSPPIC 319
Score = 57.2 bits (132), Expect = 3e-07
Identities = 34/112 (30%), Positives = 47/112 (41%), Gaps = 4/112 (3%)
Query: 485 NGHKA-GSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNC-GTPTIHKGSFVLI 542
N H + G+ +C+ G L G SV C WSG C+ + C P I G++
Sbjct: 78 NYHSSLGTRCELSCDRGFRLIGRRSVQCLPSRRWSGTA-YCRQMRCHALPFITSGTYTCT 136
Query: 543 NGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVP 594
NG S ++C Y L G +C DG+WS P C P+ P
Sbjct: 137 NGVLL-DSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVDIDPPKIRCP 187
Score = 44.8 bits (101), Expect = 0.002
Identities = 19/50 (38%), Positives = 28/50 (56%), Gaps = 1/50 (2%)
Query: 857 GLLVVTSTL-SIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPI 905
G L TS + G Y C+ GY+ +G +R C S QW+G+ P+C P+
Sbjct: 273 GYLTCTSAGDNYGATCEYHCDGGYDRQGTPSRVCQSSRQWSGSPPICAPM 322
Score = 41.9 bits (94), Expect = 0.012
Identities = 47/197 (23%), Positives = 78/197 (39%), Gaps = 20/197 (10%)
Query: 287 PGLTSRTWQWVDGELV-SKPSWGKDQPNNYNGEQNCVVLDGGRGWLWNDVGC-NLDYLHW 344
P +TS T+ +G L+ S+ + + G+++ + ++ GR W + C ++D
Sbjct: 126 PFITSGTYTCTNGVLLDSRCDYSCSSGYHLEGDRSRICMEDGR-WSGGEPVCVDIDPPKI 184
Query: 345 ICQYLPPTCGSPDKLLNTTI----LGNDYDVGS--RIVYKCPE--GHMLLGDKS-RHCKK 395
C + P+KL L D G+ R+ + PE H G+ R+
Sbjct: 185 RCPHSREKMAEPEKLTARVYWDPPLVKDSADGTITRVTLRGPEPGSHFPEGEHVIRYTAY 244
Query: 396 DGFWSGAPPSCKYV------NCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNP 449
D ++ A SCK++ C L P + G + +GA Y C + G P
Sbjct: 245 DRAYNRA--SCKFIVKVQVRRCPTLKPPQHGYLTCTSAGDNYGATCEYHCDGGYDRQGTP 302
Query: 450 ERTCGDEGIWDGEAPRC 466
R C W G P C
Sbjct: 303 SRVCQSSRQWSGSPPIC 319
Score = 38.3 bits (85), Expect = 0.15
Identities = 15/49 (30%), Positives = 25/49 (51%)
Query: 914 ENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
++G + ++ +G++ EY+C Y R G R C +WSG P C
Sbjct: 271 QHGYLTCTSAGDNYGATCEYHCDGGYDRQGTPSRVCQSSRQWSGSPPIC 319
Score = 33.9 bits (74), Expect = 3.2
Identities = 13/35 (37%), Positives = 15/35 (42%)
Query: 24 GTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
G Y CD GY+ G R C W+ PP C
Sbjct: 285 GATCEYHCDGGYDRQGTPSRVCQSSRQWSGSPPIC 319
>BC126115-1|AAI26116.1| 1024|Homo sapiens seizure related 6 homolog
(mouse)-like protein.
Length = 1024
Score = 89.0 bits (211), Expect = 8e-17
Identities = 54/190 (28%), Positives = 85/190 (44%), Gaps = 12/190 (6%)
Query: 785 CGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEIT 844
C + I+NG T GA YQCD +++ G CQ + +WS +PP C++I
Sbjct: 745 CSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKIM 804
Query: 845 -CPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQ----WNGTV 899
C DP S L+ L +G Y C G+ L+G TC S+ W +
Sbjct: 805 YCTDPGE--VDHSTRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRL 862
Query: 900 PVCI---PIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCL--DDGR 954
P C+ + C +PG ENG ++ L G S+ + C ++ +G +C+
Sbjct: 863 PHCVSEESLACDNPGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCILGQPSH 922
Query: 955 WSGEEPSCEL 964
W+G P C++
Sbjct: 923 WNGPLPVCKV 932
Score = 84.6 bits (200), Expect = 2e-15
Identities = 49/168 (29%), Positives = 78/168 (46%), Gaps = 14/168 (8%)
Query: 746 GALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYV-DCGNPGRIENGKVTLPSNATF 804
GA + Y+C+ GY ++G TC+ + WS P C+ + C +PG +++ +
Sbjct: 766 GARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKIMYCTDPGEVDHSTRLISDPVLL 825
Query: 805 YGATAFYQCDENWELEGVIRRMC--QENGT--WSLEPPIC---KEITCPDPSAQIKAGSG 857
G T Y C+ + LEG C +E GT W+ P C + + C +P +G
Sbjct: 826 VGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHCVSEESLACDNPGL---PENG 882
Query: 858 LLVVTSTLSIGGEA-HYQCERGYNLKGHQTRTCI--SKGQWNGTVPVC 902
++ L + GE+ + C G+ L G T CI WNG +PVC
Sbjct: 883 YQILYKRLYLPGESLTFMCYEGFELMGEVTIRCILGQPSHWNGPLPVC 930
Score = 74.1 bits (174), Expect = 2e-12
Identities = 60/206 (29%), Positives = 84/206 (40%), Gaps = 29/206 (14%)
Query: 646 CGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIR 705
C LP + G + G+ I Y C Y +VG TC + WS P CE+I
Sbjct: 745 CSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKIM 804
Query: 706 -CSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESL 764
C+DP + H LI SD +G ++Y C G+ + G SL
Sbjct: 805 YCTDP------------GEVDHSTRLI--SDP-----VLLVGTTIQYTCNPGFVLEGSSL 845
Query: 765 STC--EDNGQ--WSGTTPTC---QYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENW 817
TC + G W+ P C + + C NPG ENG L G + + C E +
Sbjct: 846 LTCYSRETGTPIWTSRLPHCVSEESLACDNPGLPENGYQILYKRLYLPGESLTFMCYEGF 905
Query: 818 ELEG--VIRRMCQENGTWSLEPPICK 841
EL G IR + + W+ P+CK
Sbjct: 906 ELMGEVTIRCILGQPSHWNGPLPVCK 931
Score = 68.1 bits (159), Expect = 2e-10
Identities = 47/169 (27%), Positives = 72/169 (42%), Gaps = 18/169 (10%)
Query: 372 GSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSC-KYVNCGGLTPIEDGDVALIDNRTT 430
G+RI Y+C G+ ++G + C+ D WS PP C K + C ++ + D
Sbjct: 766 GARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKIMYCTDPGEVDHSTRLISDPVLL 825
Query: 431 HGARALYSCRENFTLVGNPERTC--GDEG--IWDGEAPRCLFDWCPDPPAVSNASVTVNG 486
G Y+C F L G+ TC + G IW P C+ + + A N + NG
Sbjct: 826 VGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHCVSE---ESLACDNPGLPENG 882
Query: 487 HK--------AGSLASYTCENGHILSGSTSVTCTLG--GAWSGVPPSCK 525
++ G ++ C G L G ++ C LG W+G P CK
Sbjct: 883 YQILYKRLYLPGESLTFMCYEGFELMGEVTIRCILGQPSHWNGPLPVCK 931
Score = 66.5 bits (155), Expect = 5e-10
Identities = 51/204 (25%), Positives = 85/204 (41%), Gaps = 25/204 (12%)
Query: 587 SCPE-PEVPSGGYMEAFDYYVHST-INFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYI 644
SC + PE+ +G + V I + C+ G+ ++G L CQ D WS D P CE I
Sbjct: 744 SCSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKI 803
Query: 645 -DCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTC----TEEFQWSDSSP 699
C + + T + + +G+ IQY+C + L G TC T W+ P
Sbjct: 804 MYCTDPGEVDHSTRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLP 863
Query: 700 RCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKV 759
C V+E+S+ +G+ ++ Y G + + C +G+++
Sbjct: 864 HC---------VSEESLACDNPGLPENGYQIL-------YKRLYLPGESLTFMCYEGFEL 907
Query: 760 IGESLSTC--EDNGQWSGTTPTCQ 781
+GE C W+G P C+
Sbjct: 908 MGEVTIRCILGQPSHWNGPLPVCK 931
Score = 66.1 bits (154), Expect = 6e-10
Identities = 46/189 (24%), Positives = 78/189 (41%), Gaps = 13/189 (6%)
Query: 410 NCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRC-LF 468
+C L I++G GAR Y C + +VG+ TC + W + P C
Sbjct: 744 SCSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKI 803
Query: 469 DWCPDPPAVSNASVTVNGH--KAGSLASYTCENGHILSGSTSVTC----TLGGAWSGVPP 522
+C DP V +++ ++ G+ YTC G +L GS+ +TC T W+ P
Sbjct: 804 MYCTDPGEVDHSTRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLP 863
Query: 523 SC---KYVNCGTPTIHKGSF-VLINGTTTYGSIAQFTCEPDYWLNGAEELVC--NRDGKW 576
C + + C P + + + +L G F C + L G + C + W
Sbjct: 864 HCVSEESLACDNPGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCILGQPSHW 923
Query: 577 SYDIPSCEL 585
+ +P C++
Sbjct: 924 NGPLPVCKV 932
Score = 59.3 bits (137), Expect = 7e-08
Identities = 51/184 (27%), Positives = 77/184 (41%), Gaps = 14/184 (7%)
Query: 532 PTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCE-LTSCPE 590
P I G + G+ + C+P Y + G++ L C D WS D P CE + C +
Sbjct: 749 PEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKIMYCTD 808
Query: 591 P-EVP-SGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVC--QQDGE--WSGDSPTC--- 641
P EV S + V +TI + C G L G L C ++ G W+ P C
Sbjct: 809 PGEVDHSTRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHCVSE 868
Query: 642 EYIDCGKLPTLPYGTMELLNGTTHL-GSVIQYSCTTNYRLVGPVRRTCT--EEFQWSDSS 698
E + C P LP ++L +L G + + C + L+G V C + W+
Sbjct: 869 ESLACDN-PGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCILGQPSHWNGPL 927
Query: 699 PRCE 702
P C+
Sbjct: 928 PVCK 931
Score = 42.3 bits (95), Expect = 0.009
Identities = 19/45 (42%), Positives = 24/45 (53%), Gaps = 2/45 (4%)
Query: 860 VVTSTLSIGGEAHYQCERGYNLKGHQTRTCI--SKGQWNGTVPVC 902
V L GG AH+ C GY L+G + TCI SK W+ P+C
Sbjct: 404 VTVMDLHSGGVAHFHCHLGYELQGAKILTCINASKPHWSSQEPIC 448
Score = 39.5 bits (88), Expect = 0.064
Identities = 14/38 (36%), Positives = 21/38 (55%)
Query: 21 IVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
+V G Y+CD GY++ G+ C W+ +PPFC
Sbjct: 763 LVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFC 800
Score = 39.1 bits (87), Expect = 0.085
Identities = 20/65 (30%), Positives = 26/65 (40%), Gaps = 3/65 (4%)
Query: 585 LTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVC--QQDGEWSGDSPTCE 642
+ SC P P G + D + +FHC G++L G L C WS P C
Sbjct: 390 MLSCNFPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKILTCINASKPHWSSQEPICS 449
Query: 643 YIDCG 647
CG
Sbjct: 450 -APCG 453
Score = 35.9 bits (79), Expect = 0.79
Identities = 19/59 (32%), Positives = 28/59 (47%), Gaps = 3/59 (5%)
Query: 528 NCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAE---ELVCNRDGKWSYDIPSC 583
+C P I G+F + T G+I +FTC+P + L E + RD W+ P C
Sbjct: 566 HCYEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPYWNDTEPLC 624
Score = 32.7 bits (71), Expect = 7.4
Identities = 18/66 (27%), Positives = 32/66 (48%), Gaps = 4/66 (6%)
Query: 588 CPEPEVPSGGYMEAFDYY-VHSTINFHCEAGHKLIGEPNLV-C--QQDGEWSGDSPTCEY 643
C EP + +G + + Y + + + F C+ GH L P ++ C +D W+ P C
Sbjct: 567 CYEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPYWNDTEPLCRA 626
Query: 644 IDCGKL 649
+ G+L
Sbjct: 627 MCGGEL 632
>AY358405-1|AAQ88771.1| 1023|Homo sapiens SEZ6L protein.
Length = 1023
Score = 89.0 bits (211), Expect = 8e-17
Identities = 54/190 (28%), Positives = 85/190 (44%), Gaps = 12/190 (6%)
Query: 785 CGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEIT 844
C + I+NG T GA YQCD +++ G CQ + +WS +PP C++I
Sbjct: 745 CSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKIM 804
Query: 845 -CPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQ----WNGTV 899
C DP S L+ L +G Y C G+ L+G TC S+ W +
Sbjct: 805 YCTDPGE--VDHSTRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRL 862
Query: 900 PVCI---PIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCL--DDGR 954
P C+ + C +PG ENG ++ L G S+ + C ++ +G +C+
Sbjct: 863 PHCVSEESLACDNPGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCILGQPSH 922
Query: 955 WSGEEPSCEL 964
W+G P C++
Sbjct: 923 WNGPLPVCKV 932
Score = 84.6 bits (200), Expect = 2e-15
Identities = 49/168 (29%), Positives = 78/168 (46%), Gaps = 14/168 (8%)
Query: 746 GALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYV-DCGNPGRIENGKVTLPSNATF 804
GA + Y+C+ GY ++G TC+ + WS P C+ + C +PG +++ +
Sbjct: 766 GARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKIMYCTDPGEVDHSTRLISDPVLL 825
Query: 805 YGATAFYQCDENWELEGVIRRMC--QENGT--WSLEPPIC---KEITCPDPSAQIKAGSG 857
G T Y C+ + LEG C +E GT W+ P C + + C +P +G
Sbjct: 826 VGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHCVSEESLACDNPGL---PENG 882
Query: 858 LLVVTSTLSIGGEA-HYQCERGYNLKGHQTRTCI--SKGQWNGTVPVC 902
++ L + GE+ + C G+ L G T CI WNG +PVC
Sbjct: 883 YQILYKRLYLPGESLTFMCYEGFELMGEVTIRCILGQPSHWNGPLPVC 930
Score = 74.1 bits (174), Expect = 2e-12
Identities = 60/206 (29%), Positives = 84/206 (40%), Gaps = 29/206 (14%)
Query: 646 CGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIR 705
C LP + G + G+ I Y C Y +VG TC + WS P CE+I
Sbjct: 745 CSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKIM 804
Query: 706 -CSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESL 764
C+DP + H LI SD +G ++Y C G+ + G SL
Sbjct: 805 YCTDP------------GEVDHSTRLI--SDP-----VLLVGTTIQYTCNPGFVLEGSSL 845
Query: 765 STC--EDNGQ--WSGTTPTC---QYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENW 817
TC + G W+ P C + + C NPG ENG L G + + C E +
Sbjct: 846 LTCYSRETGTPIWTSRLPHCVSEESLACDNPGLPENGYQILYKRLYLPGESLTFMCYEGF 905
Query: 818 ELEG--VIRRMCQENGTWSLEPPICK 841
EL G IR + + W+ P+CK
Sbjct: 906 ELMGEVTIRCILGQPSHWNGPLPVCK 931
Score = 68.1 bits (159), Expect = 2e-10
Identities = 47/169 (27%), Positives = 72/169 (42%), Gaps = 18/169 (10%)
Query: 372 GSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSC-KYVNCGGLTPIEDGDVALIDNRTT 430
G+RI Y+C G+ ++G + C+ D WS PP C K + C ++ + D
Sbjct: 766 GARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKIMYCTDPGEVDHSTRLISDPVLL 825
Query: 431 HGARALYSCRENFTLVGNPERTC--GDEG--IWDGEAPRCLFDWCPDPPAVSNASVTVNG 486
G Y+C F L G+ TC + G IW P C+ + + A N + NG
Sbjct: 826 VGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHCVSE---ESLACDNPGLPENG 882
Query: 487 HK--------AGSLASYTCENGHILSGSTSVTCTLG--GAWSGVPPSCK 525
++ G ++ C G L G ++ C LG W+G P CK
Sbjct: 883 YQILYKRLYLPGESLTFMCYEGFELMGEVTIRCILGQPSHWNGPLPVCK 931
Score = 66.5 bits (155), Expect = 5e-10
Identities = 51/204 (25%), Positives = 85/204 (41%), Gaps = 25/204 (12%)
Query: 587 SCPE-PEVPSGGYMEAFDYYVHST-INFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYI 644
SC + PE+ +G + V I + C+ G+ ++G L CQ D WS D P CE I
Sbjct: 744 SCSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKI 803
Query: 645 -DCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTC----TEEFQWSDSSP 699
C + + T + + +G+ IQY+C + L G TC T W+ P
Sbjct: 804 MYCTDPGEVDHSTRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLP 863
Query: 700 RCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKV 759
C V+E+S+ +G+ ++ Y G + + C +G+++
Sbjct: 864 HC---------VSEESLACDNPGLPENGYQIL-------YKRLYLPGESLTFMCYEGFEL 907
Query: 760 IGESLSTC--EDNGQWSGTTPTCQ 781
+GE C W+G P C+
Sbjct: 908 MGEVTIRCILGQPSHWNGPLPVCK 931
Score = 66.1 bits (154), Expect = 6e-10
Identities = 46/189 (24%), Positives = 78/189 (41%), Gaps = 13/189 (6%)
Query: 410 NCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRC-LF 468
+C L I++G GAR Y C + +VG+ TC + W + P C
Sbjct: 744 SCSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKI 803
Query: 469 DWCPDPPAVSNASVTVNGH--KAGSLASYTCENGHILSGSTSVTC----TLGGAWSGVPP 522
+C DP V +++ ++ G+ YTC G +L GS+ +TC T W+ P
Sbjct: 804 MYCTDPGEVDHSTRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLP 863
Query: 523 SC---KYVNCGTPTIHKGSF-VLINGTTTYGSIAQFTCEPDYWLNGAEELVC--NRDGKW 576
C + + C P + + + +L G F C + L G + C + W
Sbjct: 864 HCVSEESLACDNPGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCILGQPSHW 923
Query: 577 SYDIPSCEL 585
+ +P C++
Sbjct: 924 NGPLPVCKV 932
Score = 59.3 bits (137), Expect = 7e-08
Identities = 51/184 (27%), Positives = 77/184 (41%), Gaps = 14/184 (7%)
Query: 532 PTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCE-LTSCPE 590
P I G + G+ + C+P Y + G++ L C D WS D P CE + C +
Sbjct: 749 PEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKIMYCTD 808
Query: 591 P-EVP-SGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVC--QQDGE--WSGDSPTC--- 641
P EV S + V +TI + C G L G L C ++ G W+ P C
Sbjct: 809 PGEVDHSTRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHCVSE 868
Query: 642 EYIDCGKLPTLPYGTMELLNGTTHL-GSVIQYSCTTNYRLVGPVRRTCT--EEFQWSDSS 698
E + C P LP ++L +L G + + C + L+G V C + W+
Sbjct: 869 ESLACDN-PGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCILGQPSHWNGPL 927
Query: 699 PRCE 702
P C+
Sbjct: 928 PVCK 931
Score = 42.3 bits (95), Expect = 0.009
Identities = 19/45 (42%), Positives = 24/45 (53%), Gaps = 2/45 (4%)
Query: 860 VVTSTLSIGGEAHYQCERGYNLKGHQTRTCI--SKGQWNGTVPVC 902
V L GG AH+ C GY L+G + TCI SK W+ P+C
Sbjct: 404 VTVMDLHSGGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPIC 448
Score = 39.5 bits (88), Expect = 0.064
Identities = 20/65 (30%), Positives = 26/65 (40%), Gaps = 3/65 (4%)
Query: 585 LTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVC--QQDGEWSGDSPTCE 642
+ SC P P G + D + +FHC G++L G L C WS P C
Sbjct: 390 MLSCNFPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPICS 449
Query: 643 YIDCG 647
CG
Sbjct: 450 -APCG 453
Score = 39.5 bits (88), Expect = 0.064
Identities = 14/38 (36%), Positives = 21/38 (55%)
Query: 21 IVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
+V G Y+CD GY++ G+ C W+ +PPFC
Sbjct: 763 LVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFC 800
Score = 35.9 bits (79), Expect = 0.79
Identities = 19/59 (32%), Positives = 28/59 (47%), Gaps = 3/59 (5%)
Query: 528 NCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAE---ELVCNRDGKWSYDIPSC 583
+C P I G+F + T G+I +FTC+P + L E + RD W+ P C
Sbjct: 566 HCYEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPYWNDTEPLC 624
Score = 33.1 bits (72), Expect = 5.6
Identities = 17/59 (28%), Positives = 29/59 (49%), Gaps = 5/59 (8%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQREC--TLRGDWTLEPPFC 58
C P P + V++ + + +G +A + C GYEL GA+ C + W+ + P C
Sbjct: 393 CNFPRRPDSGDVTVMD---LHSGGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPIC 448
Score = 32.7 bits (71), Expect = 7.4
Identities = 18/66 (27%), Positives = 32/66 (48%), Gaps = 4/66 (6%)
Query: 588 CPEPEVPSGGYMEAFDYY-VHSTINFHCEAGHKLIGEPNLV-C--QQDGEWSGDSPTCEY 643
C EP + +G + + Y + + + F C+ GH L P ++ C +D W+ P C
Sbjct: 567 CYEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPYWNDTEPLCRA 626
Query: 644 IDCGKL 649
+ G+L
Sbjct: 627 MCGGEL 632
Score = 32.3 bits (70), Expect = 9.7
Identities = 19/62 (30%), Positives = 26/62 (41%), Gaps = 3/62 (4%)
Query: 471 CPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGA--WSGVPPSCKYVN 528
C P + VTV +G +A + C G+ L G+ +TC WS P C
Sbjct: 393 CNFPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPICS-AP 451
Query: 529 CG 530
CG
Sbjct: 452 CG 453
>AL050253-1|CAB43355.1| 792|Homo sapiens hypothetical protein
protein.
Length = 792
Score = 89.0 bits (211), Expect = 8e-17
Identities = 54/190 (28%), Positives = 85/190 (44%), Gaps = 12/190 (6%)
Query: 785 CGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEIT 844
C + I+NG T GA YQCD +++ G CQ + +WS +PP C++I
Sbjct: 518 CSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKIM 577
Query: 845 -CPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQ----WNGTV 899
C DP S L+ L +G Y C G+ L+G TC S+ W +
Sbjct: 578 YCTDPGE--VDHSTRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRL 635
Query: 900 PVCI---PIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCL--DDGR 954
P C+ + C +PG ENG ++ L G S+ + C ++ +G +C+
Sbjct: 636 PHCVSEESLACDNPGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCILGQPSH 695
Query: 955 WSGEEPSCEL 964
W+G P C++
Sbjct: 696 WNGPLPVCKV 705
Score = 84.6 bits (200), Expect = 2e-15
Identities = 49/168 (29%), Positives = 78/168 (46%), Gaps = 14/168 (8%)
Query: 746 GALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYV-DCGNPGRIENGKVTLPSNATF 804
GA + Y+C+ GY ++G TC+ + WS P C+ + C +PG +++ +
Sbjct: 539 GARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKIMYCTDPGEVDHSTRLISDPVLL 598
Query: 805 YGATAFYQCDENWELEGVIRRMC--QENGT--WSLEPPIC---KEITCPDPSAQIKAGSG 857
G T Y C+ + LEG C +E GT W+ P C + + C +P +G
Sbjct: 599 VGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHCVSEESLACDNPGL---PENG 655
Query: 858 LLVVTSTLSIGGEA-HYQCERGYNLKGHQTRTCI--SKGQWNGTVPVC 902
++ L + GE+ + C G+ L G T CI WNG +PVC
Sbjct: 656 YQILYKRLYLPGESLTFMCYEGFELMGEVTIRCILGQPSHWNGPLPVC 703
Score = 74.1 bits (174), Expect = 2e-12
Identities = 60/206 (29%), Positives = 84/206 (40%), Gaps = 29/206 (14%)
Query: 646 CGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIR 705
C LP + G + G+ I Y C Y +VG TC + WS P CE+I
Sbjct: 518 CSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKIM 577
Query: 706 -CSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESL 764
C+DP + H LI SD +G ++Y C G+ + G SL
Sbjct: 578 YCTDP------------GEVDHSTRLI--SDP-----VLLVGTTIQYTCNPGFVLEGSSL 618
Query: 765 STC--EDNGQ--WSGTTPTC---QYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENW 817
TC + G W+ P C + + C NPG ENG L G + + C E +
Sbjct: 619 LTCYSRETGTPIWTSRLPHCVSEESLACDNPGLPENGYQILYKRLYLPGESLTFMCYEGF 678
Query: 818 ELEG--VIRRMCQENGTWSLEPPICK 841
EL G IR + + W+ P+CK
Sbjct: 679 ELMGEVTIRCILGQPSHWNGPLPVCK 704
Score = 68.1 bits (159), Expect = 2e-10
Identities = 47/169 (27%), Positives = 72/169 (42%), Gaps = 18/169 (10%)
Query: 372 GSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSC-KYVNCGGLTPIEDGDVALIDNRTT 430
G+RI Y+C G+ ++G + C+ D WS PP C K + C ++ + D
Sbjct: 539 GARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKIMYCTDPGEVDHSTRLISDPVLL 598
Query: 431 HGARALYSCRENFTLVGNPERTC--GDEG--IWDGEAPRCLFDWCPDPPAVSNASVTVNG 486
G Y+C F L G+ TC + G IW P C+ + + A N + NG
Sbjct: 599 VGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHCVSE---ESLACDNPGLPENG 655
Query: 487 HK--------AGSLASYTCENGHILSGSTSVTCTLG--GAWSGVPPSCK 525
++ G ++ C G L G ++ C LG W+G P CK
Sbjct: 656 YQILYKRLYLPGESLTFMCYEGFELMGEVTIRCILGQPSHWNGPLPVCK 704
Score = 66.5 bits (155), Expect = 5e-10
Identities = 51/204 (25%), Positives = 85/204 (41%), Gaps = 25/204 (12%)
Query: 587 SCPE-PEVPSGGYMEAFDYYVHST-INFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYI 644
SC + PE+ +G + V I + C+ G+ ++G L CQ D WS D P CE I
Sbjct: 517 SCSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKI 576
Query: 645 -DCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTC----TEEFQWSDSSP 699
C + + T + + +G+ IQY+C + L G TC T W+ P
Sbjct: 577 MYCTDPGEVDHSTRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLP 636
Query: 700 RCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKV 759
C V+E+S+ +G+ ++ Y G + + C +G+++
Sbjct: 637 HC---------VSEESLACDNPGLPENGYQIL-------YKRLYLPGESLTFMCYEGFEL 680
Query: 760 IGESLSTC--EDNGQWSGTTPTCQ 781
+GE C W+G P C+
Sbjct: 681 MGEVTIRCILGQPSHWNGPLPVCK 704
Score = 66.1 bits (154), Expect = 6e-10
Identities = 46/189 (24%), Positives = 78/189 (41%), Gaps = 13/189 (6%)
Query: 410 NCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRC-LF 468
+C L I++G GAR Y C + +VG+ TC + W + P C
Sbjct: 517 SCSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKI 576
Query: 469 DWCPDPPAVSNASVTVNGH--KAGSLASYTCENGHILSGSTSVTC----TLGGAWSGVPP 522
+C DP V +++ ++ G+ YTC G +L GS+ +TC T W+ P
Sbjct: 577 MYCTDPGEVDHSTRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLP 636
Query: 523 SC---KYVNCGTPTIHKGSF-VLINGTTTYGSIAQFTCEPDYWLNGAEELVC--NRDGKW 576
C + + C P + + + +L G F C + L G + C + W
Sbjct: 637 HCVSEESLACDNPGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCILGQPSHW 696
Query: 577 SYDIPSCEL 585
+ +P C++
Sbjct: 697 NGPLPVCKV 705
Score = 59.3 bits (137), Expect = 7e-08
Identities = 51/184 (27%), Positives = 77/184 (41%), Gaps = 14/184 (7%)
Query: 532 PTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCE-LTSCPE 590
P I G + G+ + C+P Y + G++ L C D WS D P CE + C +
Sbjct: 522 PEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKIMYCTD 581
Query: 591 P-EVP-SGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVC--QQDGE--WSGDSPTC--- 641
P EV S + V +TI + C G L G L C ++ G W+ P C
Sbjct: 582 PGEVDHSTRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHCVSE 641
Query: 642 EYIDCGKLPTLPYGTMELLNGTTHL-GSVIQYSCTTNYRLVGPVRRTCT--EEFQWSDSS 698
E + C P LP ++L +L G + + C + L+G V C + W+
Sbjct: 642 ESLACDN-PGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCILGQPSHWNGPL 700
Query: 699 PRCE 702
P C+
Sbjct: 701 PVCK 704
Score = 42.3 bits (95), Expect = 0.009
Identities = 19/45 (42%), Positives = 24/45 (53%), Gaps = 2/45 (4%)
Query: 860 VVTSTLSIGGEAHYQCERGYNLKGHQTRTCI--SKGQWNGTVPVC 902
V L GG AH+ C GY L+G + TCI SK W+ P+C
Sbjct: 177 VTVMDLHSGGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPIC 221
Score = 39.5 bits (88), Expect = 0.064
Identities = 20/65 (30%), Positives = 26/65 (40%), Gaps = 3/65 (4%)
Query: 585 LTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVC--QQDGEWSGDSPTCE 642
+ SC P P G + D + +FHC G++L G L C WS P C
Sbjct: 163 MLSCNFPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPICS 222
Query: 643 YIDCG 647
CG
Sbjct: 223 -APCG 226
Score = 39.5 bits (88), Expect = 0.064
Identities = 14/38 (36%), Positives = 21/38 (55%)
Query: 21 IVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
+V G Y+CD GY++ G+ C W+ +PPFC
Sbjct: 536 LVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFC 573
Score = 35.9 bits (79), Expect = 0.79
Identities = 19/59 (32%), Positives = 28/59 (47%), Gaps = 3/59 (5%)
Query: 528 NCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAE---ELVCNRDGKWSYDIPSC 583
+C P I G+F + T G+I +FTC+P + L E + RD W+ P C
Sbjct: 339 HCYEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPYWNDTEPLC 397
Score = 33.1 bits (72), Expect = 5.6
Identities = 17/59 (28%), Positives = 29/59 (49%), Gaps = 5/59 (8%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQREC--TLRGDWTLEPPFC 58
C P P + V++ + + +G +A + C GYEL GA+ C + W+ + P C
Sbjct: 166 CNFPRRPDSGDVTVMD---LHSGGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPIC 221
Score = 32.7 bits (71), Expect = 7.4
Identities = 18/66 (27%), Positives = 32/66 (48%), Gaps = 4/66 (6%)
Query: 588 CPEPEVPSGGYMEAFDYY-VHSTINFHCEAGHKLIGEPNLV-C--QQDGEWSGDSPTCEY 643
C EP + +G + + Y + + + F C+ GH L P ++ C +D W+ P C
Sbjct: 340 CYEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPYWNDTEPLCRA 399
Query: 644 IDCGKL 649
+ G+L
Sbjct: 400 MCGGEL 405
Score = 32.3 bits (70), Expect = 9.7
Identities = 19/62 (30%), Positives = 26/62 (41%), Gaps = 3/62 (4%)
Query: 471 CPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGA--WSGVPPSCKYVN 528
C P + VTV +G +A + C G+ L G+ +TC WS P C
Sbjct: 166 CNFPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPICS-AP 224
Query: 529 CG 530
CG
Sbjct: 225 CG 226
>AB041736-1|BAB40970.1| 1024|Homo sapiens SEZ6L protein.
Length = 1024
Score = 89.0 bits (211), Expect = 8e-17
Identities = 54/190 (28%), Positives = 85/190 (44%), Gaps = 12/190 (6%)
Query: 785 CGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEIT 844
C + I+NG T GA YQCD +++ G CQ + +WS +PP C++I
Sbjct: 745 CSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKIM 804
Query: 845 -CPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQ----WNGTV 899
C DP S L+ L +G Y C G+ L+G TC S+ W +
Sbjct: 805 YCTDPGE--VDHSTRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRL 862
Query: 900 PVCI---PIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCL--DDGR 954
P C+ + C +PG ENG ++ L G S+ + C ++ +G +C+
Sbjct: 863 PHCVSEESLACDNPGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCILGQPSH 922
Query: 955 WSGEEPSCEL 964
W+G P C++
Sbjct: 923 WNGPLPVCKV 932
Score = 84.6 bits (200), Expect = 2e-15
Identities = 49/168 (29%), Positives = 78/168 (46%), Gaps = 14/168 (8%)
Query: 746 GALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYV-DCGNPGRIENGKVTLPSNATF 804
GA + Y+C+ GY ++G TC+ + WS P C+ + C +PG +++ +
Sbjct: 766 GARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKIMYCTDPGEVDHSTRLISDPVLL 825
Query: 805 YGATAFYQCDENWELEGVIRRMC--QENGT--WSLEPPIC---KEITCPDPSAQIKAGSG 857
G T Y C+ + LEG C +E GT W+ P C + + C +P +G
Sbjct: 826 VGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHCVSEESLACDNPGL---PENG 882
Query: 858 LLVVTSTLSIGGEA-HYQCERGYNLKGHQTRTCI--SKGQWNGTVPVC 902
++ L + GE+ + C G+ L G T CI WNG +PVC
Sbjct: 883 YQILYKRLYLPGESLTFMCYEGFELMGEVTIRCILGQPSHWNGPLPVC 930
Score = 74.1 bits (174), Expect = 2e-12
Identities = 60/206 (29%), Positives = 84/206 (40%), Gaps = 29/206 (14%)
Query: 646 CGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIR 705
C LP + G + G+ I Y C Y +VG TC + WS P CE+I
Sbjct: 745 CSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKIM 804
Query: 706 -CSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESL 764
C+DP + H LI SD +G ++Y C G+ + G SL
Sbjct: 805 YCTDP------------GEVDHSTRLI--SDP-----VLLVGTTIQYTCNPGFVLEGSSL 845
Query: 765 STC--EDNGQ--WSGTTPTC---QYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENW 817
TC + G W+ P C + + C NPG ENG L G + + C E +
Sbjct: 846 LTCYSRETGTPIWTSRLPHCVSEESLACDNPGLPENGYQILYKRLYLPGESLTFMCYEGF 905
Query: 818 ELEG--VIRRMCQENGTWSLEPPICK 841
EL G IR + + W+ P+CK
Sbjct: 906 ELMGEVTIRCILGQPSHWNGPLPVCK 931
Score = 68.1 bits (159), Expect = 2e-10
Identities = 47/169 (27%), Positives = 72/169 (42%), Gaps = 18/169 (10%)
Query: 372 GSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSC-KYVNCGGLTPIEDGDVALIDNRTT 430
G+RI Y+C G+ ++G + C+ D WS PP C K + C ++ + D
Sbjct: 766 GARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKIMYCTDPGEVDHSTRLISDPVLL 825
Query: 431 HGARALYSCRENFTLVGNPERTC--GDEG--IWDGEAPRCLFDWCPDPPAVSNASVTVNG 486
G Y+C F L G+ TC + G IW P C+ + + A N + NG
Sbjct: 826 VGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHCVSE---ESLACDNPGLPENG 882
Query: 487 HK--------AGSLASYTCENGHILSGSTSVTCTLG--GAWSGVPPSCK 525
++ G ++ C G L G ++ C LG W+G P CK
Sbjct: 883 YQILYKRLYLPGESLTFMCYEGFELMGEVTIRCILGQPSHWNGPLPVCK 931
Score = 66.5 bits (155), Expect = 5e-10
Identities = 51/204 (25%), Positives = 85/204 (41%), Gaps = 25/204 (12%)
Query: 587 SCPE-PEVPSGGYMEAFDYYVHST-INFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYI 644
SC + PE+ +G + V I + C+ G+ ++G L CQ D WS D P CE I
Sbjct: 744 SCSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKI 803
Query: 645 -DCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTC----TEEFQWSDSSP 699
C + + T + + +G+ IQY+C + L G TC T W+ P
Sbjct: 804 MYCTDPGEVDHSTRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLP 863
Query: 700 RCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKV 759
C V+E+S+ +G+ ++ Y G + + C +G+++
Sbjct: 864 HC---------VSEESLACDNPGLPENGYQIL-------YKRLYLPGESLTFMCYEGFEL 907
Query: 760 IGESLSTC--EDNGQWSGTTPTCQ 781
+GE C W+G P C+
Sbjct: 908 MGEVTIRCILGQPSHWNGPLPVCK 931
Score = 66.1 bits (154), Expect = 6e-10
Identities = 46/189 (24%), Positives = 78/189 (41%), Gaps = 13/189 (6%)
Query: 410 NCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRC-LF 468
+C L I++G GAR Y C + +VG+ TC + W + P C
Sbjct: 744 SCSDLPEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKI 803
Query: 469 DWCPDPPAVSNASVTVNGH--KAGSLASYTCENGHILSGSTSVTC----TLGGAWSGVPP 522
+C DP V +++ ++ G+ YTC G +L GS+ +TC T W+ P
Sbjct: 804 MYCTDPGEVDHSTRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLP 863
Query: 523 SC---KYVNCGTPTIHKGSF-VLINGTTTYGSIAQFTCEPDYWLNGAEELVC--NRDGKW 576
C + + C P + + + +L G F C + L G + C + W
Sbjct: 864 HCVSEESLACDNPGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCILGQPSHW 923
Query: 577 SYDIPSCEL 585
+ +P C++
Sbjct: 924 NGPLPVCKV 932
Score = 59.3 bits (137), Expect = 7e-08
Identities = 51/184 (27%), Positives = 77/184 (41%), Gaps = 14/184 (7%)
Query: 532 PTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCE-LTSCPE 590
P I G + G+ + C+P Y + G++ L C D WS D P CE + C +
Sbjct: 749 PEIQNGWKTTSHTELVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFCEKIMYCTD 808
Query: 591 P-EVP-SGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVC--QQDGE--WSGDSPTC--- 641
P EV S + V +TI + C G L G L C ++ G W+ P C
Sbjct: 809 PGEVDHSTRLISDPVLLVGTTIQYTCNPGFVLEGSSLLTCYSRETGTPIWTSRLPHCVSE 868
Query: 642 EYIDCGKLPTLPYGTMELLNGTTHL-GSVIQYSCTTNYRLVGPVRRTCT--EEFQWSDSS 698
E + C P LP ++L +L G + + C + L+G V C + W+
Sbjct: 869 ESLACDN-PGLPENGYQILYKRLYLPGESLTFMCYEGFELMGEVTIRCILGQPSHWNGPL 927
Query: 699 PRCE 702
P C+
Sbjct: 928 PVCK 931
Score = 42.3 bits (95), Expect = 0.009
Identities = 19/45 (42%), Positives = 24/45 (53%), Gaps = 2/45 (4%)
Query: 860 VVTSTLSIGGEAHYQCERGYNLKGHQTRTCI--SKGQWNGTVPVC 902
V L GG AH+ C GY L+G + TCI SK W+ P+C
Sbjct: 404 VTVMDLHSGGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPIC 448
Score = 39.5 bits (88), Expect = 0.064
Identities = 20/65 (30%), Positives = 26/65 (40%), Gaps = 3/65 (4%)
Query: 585 LTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVC--QQDGEWSGDSPTCE 642
+ SC P P G + D + +FHC G++L G L C WS P C
Sbjct: 390 MLSCNFPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPICS 449
Query: 643 YIDCG 647
CG
Sbjct: 450 -APCG 453
Score = 39.5 bits (88), Expect = 0.064
Identities = 14/38 (36%), Positives = 21/38 (55%)
Query: 21 IVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
+V G Y+CD GY++ G+ C W+ +PPFC
Sbjct: 763 LVRGARITYQCDPGYDIVGSDTLTCQWDLSWSSDPPFC 800
Score = 35.9 bits (79), Expect = 0.79
Identities = 19/59 (32%), Positives = 28/59 (47%), Gaps = 3/59 (5%)
Query: 528 NCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAE---ELVCNRDGKWSYDIPSC 583
+C P I G+F + T G+I +FTC+P + L E + RD W+ P C
Sbjct: 566 HCYEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPYWNDTEPLC 624
Score = 33.1 bits (72), Expect = 5.6
Identities = 17/59 (28%), Positives = 29/59 (49%), Gaps = 5/59 (8%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQREC--TLRGDWTLEPPFC 58
C P P + V++ + + +G +A + C GYEL GA+ C + W+ + P C
Sbjct: 393 CNFPRRPDSGDVTVMD---LHSGGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPIC 448
Score = 32.7 bits (71), Expect = 7.4
Identities = 18/66 (27%), Positives = 32/66 (48%), Gaps = 4/66 (6%)
Query: 588 CPEPEVPSGGYMEAFDYY-VHSTINFHCEAGHKLIGEPNLV-C--QQDGEWSGDSPTCEY 643
C EP + +G + + Y + + + F C+ GH L P ++ C +D W+ P C
Sbjct: 567 CYEPYIQNGNFTTSDPTYNIGTIVEFTCDPGHSLEQGPAIIECINVRDPYWNDTEPLCRA 626
Query: 644 IDCGKL 649
+ G+L
Sbjct: 627 MCGGEL 632
Score = 32.3 bits (70), Expect = 9.7
Identities = 19/62 (30%), Positives = 26/62 (41%), Gaps = 3/62 (4%)
Query: 471 CPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGA--WSGVPPSCKYVN 528
C P + VTV +G +A + C G+ L G+ +TC WS P C
Sbjct: 393 CNFPRRPDSGDVTVMDLHSGGVAHFHCHLGYELQGAKMLTCINASKPHWSSQEPICS-AP 451
Query: 529 CG 530
CG
Sbjct: 452 CG 453
>BC020733-1|AAH20733.1| 465|Homo sapiens sushi-repeat-containing
protein, X-linked 2 protein.
Length = 465
Score = 87.8 bits (208), Expect = 2e-16
Identities = 68/250 (27%), Positives = 102/250 (40%), Gaps = 9/250 (3%)
Query: 614 CEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYS 673
C+ G +LIG ++ C WSG + C + C LP + GT NG L S YS
Sbjct: 91 CDRGFRLIGRRSVQCLPSRRWSGTA-YCRQMRCHALPFITSGTYTCTNGVL-LDSRCDYS 148
Query: 674 CTTNYRLVGPVRRTCTEEFQWSDSSPRCEEI---RCSDPIVAEKSIVSVTGNDRSH-GHT 729
C++ Y L G R C E+ +WS P C +I + P EK R +
Sbjct: 149 CSSGYHLEGDRSRICMEDGRWSGGEPVCVDIDPPKIRCPHSREKMAEPEKLTARVYWDPP 208
Query: 730 LIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPG 789
L++ S + + G +G VI + N Q C
Sbjct: 209 LVKDSADGTITRVTLRGPEPGSHFPEGEHVIRYTAYDRAYNRASCKFIVKVQVRRCPTLK 268
Query: 790 RIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPS 849
++G +T S YGA+ Y CD ++ +G R+CQ + WS PPIC + +
Sbjct: 269 PPQHGYLTCTSAGDNYGASCEYHCDGGYDRQGTPSRVCQSSRQWSGSPPICAPMKI---N 325
Query: 850 AQIKAGSGLL 859
+ + +GLL
Sbjct: 326 VNVNSAAGLL 335
Score = 71.7 bits (168), Expect = 1e-11
Identities = 35/97 (36%), Positives = 50/97 (51%), Gaps = 2/97 (2%)
Query: 866 SIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGST 925
S+G C+RG+ L G ++ C+ +W+GT C + C + I +G +NG
Sbjct: 82 SLGTRCELSCDRGFRLIGRRSVQCLPSRRWSGTA-YCRQMRCHALPFITSGTYTCTNG-V 139
Query: 926 LFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
L S +Y C S Y G R C++DGRWSG EP C
Sbjct: 140 LLDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVC 176
Score = 66.5 bits (155), Expect = 5e-10
Identities = 60/251 (23%), Positives = 96/251 (38%), Gaps = 22/251 (8%)
Query: 543 NGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPE-PEVPSGGYMEA 601
N ++ G+ + +C+ + L G + C +WS C C P + SG Y
Sbjct: 78 NYHSSLGTRCELSCDRGFRLIGRRSVQCLPSRRWS-GTAYCRQMRCHALPFITSGTYTCT 136
Query: 602 FDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLN 661
+ S ++ C +G+ L G+ + +C +DG WSG P C ID K+ P+ ++
Sbjct: 137 NGVLLDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVDIDPPKI-RCPHSREKMAE 195
Query: 662 GTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEI-----------RCSDPI 710
V G + R + P E + R S
Sbjct: 196 PEKLTARVYWDPPLVKDSADGTITRVTLRGPEPGSHFPEGEHVIRYTAYDRAYNRASCKF 255
Query: 711 VAEKSIVSV-TGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCED 769
+ + + T HG+ L TS G+ Y GA +Y C+ GY G C+
Sbjct: 256 IVKVQVRRCPTLKPPQHGY-LTCTS----AGDNY--GASCEYHCDGGYDRQGTPSRVCQS 308
Query: 770 NGQWSGTTPTC 780
+ QWSG+ P C
Sbjct: 309 SRQWSGSPPIC 319
Score = 62.5 bits (145), Expect = 8e-09
Identities = 31/102 (30%), Positives = 50/102 (49%), Gaps = 2/102 (1%)
Query: 745 IGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATF 804
+G + C++G+++IG C + +WSGT C+ + C I +G T +N
Sbjct: 83 LGTRCELSCDRGFRLIGRRSVQCLPSRRWSGTA-YCRQMRCHALPFITSGTYTC-TNGVL 140
Query: 805 YGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCP 846
+ Y C + LEG R+C E+G WS P+C +I P
Sbjct: 141 LDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVDIDPP 182
Score = 58.4 bits (135), Expect = 1e-07
Identities = 34/121 (28%), Positives = 55/121 (45%), Gaps = 9/121 (7%)
Query: 791 IENGKVTL--PSNATFY---GATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITC 845
I++G+ T P ++ G CD + L G C + WS C+++ C
Sbjct: 64 IQDGEATCYSPKGGNYHSSLGTRCELSCDRGFRLIGRRSVQCLPSRRWS-GTAYCRQMRC 122
Query: 846 PDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPI 905
A SG T+ + + Y C GY+L+G ++R C+ G+W+G PVC+ I
Sbjct: 123 ---HALPFITSGTYTCTNGVLLDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVDI 179
Query: 906 D 906
D
Sbjct: 180 D 180
Score = 57.2 bits (132), Expect = 3e-07
Identities = 64/251 (25%), Positives = 93/251 (37%), Gaps = 40/251 (15%)
Query: 366 GNDY--DVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVA 423
G +Y +G+R C G L+G +S C WSG C+ + C L I G
Sbjct: 76 GGNYHSSLGTRCELSCDRGFRLIGRRSVQCLPSRRWSGTA-YCRQMRCHALPFITSGTYT 134
Query: 424 LIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL-FD----WCP------ 472
N +R YSC + L G+ R C ++G W G P C+ D CP
Sbjct: 135 CT-NGVLLDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVDIDPPKIRCPHSREKM 193
Query: 473 ------------DPPAVSNAS------VTVNGHKAGSLASYTCENGHILSGSTSVTCTLG 514
DPP V +++ VT+ G + G S+ E H++ T+
Sbjct: 194 AEPEKLTARVYWDPPLVKDSADGTITRVTLRGPEPG---SHFPEGEHVIR-YTAYDRAYN 249
Query: 515 GAWSGVPPSCKYVNCGT--PTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNR 572
A + C T P H G + YG+ ++ C+ Y G VC
Sbjct: 250 RASCKFIVKVQVRRCPTLKPPQH-GYLTCTSAGDNYGASCEYHCDGGYDRQGTPSRVCQS 308
Query: 573 DGKWSYDIPSC 583
+WS P C
Sbjct: 309 SRQWSGSPPIC 319
Score = 57.2 bits (132), Expect = 3e-07
Identities = 34/112 (30%), Positives = 47/112 (41%), Gaps = 4/112 (3%)
Query: 485 NGHKA-GSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNC-GTPTIHKGSFVLI 542
N H + G+ +C+ G L G SV C WSG C+ + C P I G++
Sbjct: 78 NYHSSLGTRCELSCDRGFRLIGRRSVQCLPSRRWSGTA-YCRQMRCHALPFITSGTYTCT 136
Query: 543 NGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVP 594
NG S ++C Y L G +C DG+WS P C P+ P
Sbjct: 137 NGVLL-DSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVDIDPPKIRCP 187
Score = 45.2 bits (102), Expect = 0.001
Identities = 19/50 (38%), Positives = 28/50 (56%), Gaps = 1/50 (2%)
Query: 857 GLLVVTSTL-SIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPI 905
G L TS + G Y C+ GY+ +G +R C S QW+G+ P+C P+
Sbjct: 273 GYLTCTSAGDNYGASCEYHCDGGYDRQGTPSRVCQSSRQWSGSPPICAPM 322
Score = 41.9 bits (94), Expect = 0.012
Identities = 47/197 (23%), Positives = 78/197 (39%), Gaps = 20/197 (10%)
Query: 287 PGLTSRTWQWVDGELV-SKPSWGKDQPNNYNGEQNCVVLDGGRGWLWNDVGC-NLDYLHW 344
P +TS T+ +G L+ S+ + + G+++ + ++ GR W + C ++D
Sbjct: 126 PFITSGTYTCTNGVLLDSRCDYSCSSGYHLEGDRSRICMEDGR-WSGGEPVCVDIDPPKI 184
Query: 345 ICQYLPPTCGSPDKLLNTTI----LGNDYDVGS--RIVYKCPE--GHMLLGDKS-RHCKK 395
C + P+KL L D G+ R+ + PE H G+ R+
Sbjct: 185 RCPHSREKMAEPEKLTARVYWDPPLVKDSADGTITRVTLRGPEPGSHFPEGEHVIRYTAY 244
Query: 396 DGFWSGAPPSCKYV------NCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNP 449
D ++ A SCK++ C L P + G + +GA Y C + G P
Sbjct: 245 DRAYNRA--SCKFIVKVQVRRCPTLKPPQHGYLTCTSAGDNYGASCEYHCDGGYDRQGTP 302
Query: 450 ERTCGDEGIWDGEAPRC 466
R C W G P C
Sbjct: 303 SRVCQSSRQWSGSPPIC 319
Score = 39.5 bits (88), Expect = 0.064
Identities = 16/49 (32%), Positives = 25/49 (51%)
Query: 914 ENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
++G + ++ +G+S EY+C Y R G R C +WSG P C
Sbjct: 271 QHGYLTCTSAGDNYGASCEYHCDGGYDRQGTPSRVCQSSRQWSGSPPIC 319
Score = 33.5 bits (73), Expect = 4.2
Identities = 13/35 (37%), Positives = 15/35 (42%)
Query: 24 GTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
G Y CD GY+ G R C W+ PP C
Sbjct: 285 GASCEYHCDGGYDRQGTPSRVCQSSRQWSGSPPIC 319
>AL596218-3|CAI16462.1| 317|Homo sapiens CD55 molecule, decay
accelerating factor for complement (Cromer blood group)
protein.
Length = 317
Score = 87.4 bits (207), Expect = 2e-16
Identities = 52/184 (28%), Positives = 81/184 (44%), Gaps = 13/184 (7%)
Query: 471 CPDPPAVSNASVTVNGHKA---GSLASYTCENGHI-LSGST-SVTCTLGGAWSGVPPSCK 525
C PP V NA + G + ++ +Y CE + + G SV C G WS + C
Sbjct: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCN 95
Query: 526 YVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDG---KWSYDIPS 582
+C P + + + G +G+ F+C Y L G+ C G +WS +P
Sbjct: 96 QKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPE 155
Query: 583 CELTSCP-EPEVPSGGYMEAFDYY-VHSTINFHCEAGHKLIGEPNLVC---QQDGEWSGD 637
C CP P++ +G D+Y ++ + C G +IGE ++ C +GEWSG
Sbjct: 156 CREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGP 215
Query: 638 SPTC 641
P C
Sbjct: 216 PPEC 219
Score = 84.6 bits (200), Expect = 2e-15
Identities = 56/191 (29%), Positives = 84/191 (43%), Gaps = 18/191 (9%)
Query: 784 DCGNPGRIENGKVTLPSNATFYGATAF-YQCDENW-----ELEGVIRRMCQENGTWSLEP 837
DCG P + N + L +F T Y+C+E++ E + VI C + WS
Sbjct: 35 DCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVI---CLKGSQWSDIE 91
Query: 838 PICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKG---Q 894
C + +CP+P +I+ +G + V + G + C GY L G + C+ G Q
Sbjct: 92 EFCNQKSCPNPG-EIR--NGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQ 148
Query: 895 WNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCL---D 951
W+ +P C I C +P I+NG I + SV Y C + +G C D
Sbjct: 149 WSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNND 208
Query: 952 DGRWSGEEPSC 962
+G WSG P C
Sbjct: 209 EGEWSGPPPEC 219
Score = 84.6 bits (200), Expect = 2e-15
Identities = 51/163 (31%), Positives = 75/163 (46%), Gaps = 11/163 (6%)
Query: 748 LVKYRCEKGY-KVIGESLST-CEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFY 805
++ Y+CE+ + K+ GE S C QWS C C NPG I NG++ +P F
Sbjct: 60 VITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNQKSCPNPGEIRNGQIDVPGGILF- 118
Query: 806 GATAFYQCDENWELEGVIRRMCQENGT---WSLEPPICKEITCPDPSAQIKAGSGLLVVT 862
GAT + C+ ++L G C +G+ WS P C+EI CP P QI G +
Sbjct: 119 GATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAP-PQIDNGI-IQGER 176
Query: 863 STLSIGGEAHYQCERGYNLKGHQTRTCI---SKGQWNGTVPVC 902
Y C +G+ + G + C +G+W+G P C
Sbjct: 177 DHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPEC 219
Score = 76.6 bits (180), Expect = 5e-13
Identities = 52/184 (28%), Positives = 75/184 (40%), Gaps = 14/184 (7%)
Query: 375 IVYKCPEGHMLL-GDK-SRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRTTHG 432
I YKC E + + G+K S C K WS C +C I +G + + G
Sbjct: 61 ITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNQKSCPNPGEIRNGQID-VPGGILFG 119
Query: 433 ARALYSCRENFTLVGNPERTC---GDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKA 489
A +SC + L G+ C G W P C +CP PP + N +
Sbjct: 120 ATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHY 179
Query: 490 G--SLASYTCENGHILSGSTSVTCTLG---GAWSGVPPSCKYVNCGT---PTIHKGSFVL 541
G +Y C G + G S+ CT+ G WSG PP C+ + + PT+ K + V
Sbjct: 180 GYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTVQKPTTVN 239
Query: 542 INGT 545
+ T
Sbjct: 240 VPTT 243
Score = 75.4 bits (177), Expect = 1e-12
Identities = 57/201 (28%), Positives = 82/201 (40%), Gaps = 30/201 (14%)
Query: 591 PEVPSGG-YMEAFDYYVHST-INFHCEAGH-KLIGEPN-LVCQQDGEWSGDSPTCEYIDC 646
P+VP+ +E + T I + CE K+ GE + ++C + +WS C C
Sbjct: 40 PDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNQKSC 99
Query: 647 GKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCT---EEFQWSDSSPRCEE 703
+ G +++ G G+ I +SC T Y+L G C QWSD P C E
Sbjct: 100 PNPGEIRNGQIDVPGGIL-FGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECRE 158
Query: 704 IRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGES 763
I C P + I+ +R H Y V Y C KG+ +IGE
Sbjct: 159 IYCPAPPQIDNGIIQ---GERDH----------------YGYRQSVTYACNKGFTMIGEH 199
Query: 764 LSTC---EDNGQWSGTTPTCQ 781
C D G+WSG P C+
Sbjct: 200 SIYCTVNNDEGEWSGPPPECR 220
Score = 70.1 bits (164), Expect = 4e-11
Identities = 46/185 (24%), Positives = 77/185 (41%), Gaps = 11/185 (5%)
Query: 528 NCGTPTIHKGSFVLINGTTTY--GSIAQFTCEPDYWLNGAEE--LVCNRDGKWSYDIPSC 583
+CG P + + G T++ ++ + CE + E+ ++C + +WS C
Sbjct: 35 DCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFC 94
Query: 584 ELTSCPEP-EVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDG---EWSGDSP 639
SCP P E+ +G +TI+F C G+KL G + C G +WS P
Sbjct: 95 NQKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLP 154
Query: 640 TCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCT---EEFQWSD 696
C I C P + G ++ + Y+C + ++G CT +E +WS
Sbjct: 155 ECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSG 214
Query: 697 SSPRC 701
P C
Sbjct: 215 PPPEC 219
Score = 68.1 bits (159), Expect = 2e-10
Identities = 54/207 (26%), Positives = 82/207 (39%), Gaps = 31/207 (14%)
Query: 645 DCGKLPTLPYGTMELLNGTTHL--GSVIQYSCTTNYRLVGPVRRT--CTEEFQWSDSSPR 700
DCG P +P L G T +VI Y C ++ + + + C + QWSD
Sbjct: 35 DCGLPPDVP-NAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEF 93
Query: 701 CEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVI 760
C + C +P + V G GA + + C GYK+
Sbjct: 94 CNQKSCPNPGEIRNGQIDVPGG--------------------ILFGATISFSCNTGYKLF 133
Query: 761 GESLSTCEDNG---QWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENW 817
G + S C +G QWS P C+ + C P +I+NG + + Y + Y C++ +
Sbjct: 134 GSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGF 193
Query: 818 ELEGVIRRMCQEN---GTWSLEPPICK 841
+ G C N G WS PP C+
Sbjct: 194 TMIGEHSIYCTVNNDEGEWSGPPPECR 220
Score = 34.3 bits (75), Expect = 2.4
Identities = 17/60 (28%), Positives = 28/60 (46%), Gaps = 5/60 (8%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRG---DWTLEPPFC 58
C +P N ++ +P I+ G + C+ GY+LFG+ C + G W+ P C
Sbjct: 99 CPNPGEIRNGQIDVPG--GILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPEC 156
Score = 32.3 bits (70), Expect = 9.7
Identities = 16/59 (27%), Positives = 29/59 (49%), Gaps = 2/59 (3%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGY-ELFGARQRECTLRG-DWTLEPPFC 58
CG P PNA+ ++ + T+ Y+C+E + ++ G + L+G W+ FC
Sbjct: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFC 94
>AL391597-3|CAH72947.1| 317|Homo sapiens CD55 molecule, decay
accelerating factor for complement (Cromer blood group)
protein.
Length = 317
Score = 87.4 bits (207), Expect = 2e-16
Identities = 52/184 (28%), Positives = 81/184 (44%), Gaps = 13/184 (7%)
Query: 471 CPDPPAVSNASVTVNGHKA---GSLASYTCENGHI-LSGST-SVTCTLGGAWSGVPPSCK 525
C PP V NA + G + ++ +Y CE + + G SV C G WS + C
Sbjct: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCN 95
Query: 526 YVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDG---KWSYDIPS 582
+C P + + + G +G+ F+C Y L G+ C G +WS +P
Sbjct: 96 QKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPE 155
Query: 583 CELTSCP-EPEVPSGGYMEAFDYY-VHSTINFHCEAGHKLIGEPNLVC---QQDGEWSGD 637
C CP P++ +G D+Y ++ + C G +IGE ++ C +GEWSG
Sbjct: 156 CREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGP 215
Query: 638 SPTC 641
P C
Sbjct: 216 PPEC 219
Score = 84.6 bits (200), Expect = 2e-15
Identities = 56/191 (29%), Positives = 84/191 (43%), Gaps = 18/191 (9%)
Query: 784 DCGNPGRIENGKVTLPSNATFYGATAF-YQCDENW-----ELEGVIRRMCQENGTWSLEP 837
DCG P + N + L +F T Y+C+E++ E + VI C + WS
Sbjct: 35 DCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVI---CLKGSQWSDIE 91
Query: 838 PICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKG---Q 894
C + +CP+P +I+ +G + V + G + C GY L G + C+ G Q
Sbjct: 92 EFCNQKSCPNPG-EIR--NGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQ 148
Query: 895 WNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCL---D 951
W+ +P C I C +P I+NG I + SV Y C + +G C D
Sbjct: 149 WSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNND 208
Query: 952 DGRWSGEEPSC 962
+G WSG P C
Sbjct: 209 EGEWSGPPPEC 219
Score = 84.6 bits (200), Expect = 2e-15
Identities = 51/163 (31%), Positives = 75/163 (46%), Gaps = 11/163 (6%)
Query: 748 LVKYRCEKGY-KVIGESLST-CEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFY 805
++ Y+CE+ + K+ GE S C QWS C C NPG I NG++ +P F
Sbjct: 60 VITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNQKSCPNPGEIRNGQIDVPGGILF- 118
Query: 806 GATAFYQCDENWELEGVIRRMCQENGT---WSLEPPICKEITCPDPSAQIKAGSGLLVVT 862
GAT + C+ ++L G C +G+ WS P C+EI CP P QI G +
Sbjct: 119 GATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAP-PQIDNGI-IQGER 176
Query: 863 STLSIGGEAHYQCERGYNLKGHQTRTCI---SKGQWNGTVPVC 902
Y C +G+ + G + C +G+W+G P C
Sbjct: 177 DHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPEC 219
Score = 76.6 bits (180), Expect = 5e-13
Identities = 52/184 (28%), Positives = 75/184 (40%), Gaps = 14/184 (7%)
Query: 375 IVYKCPEGHMLL-GDK-SRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRTTHG 432
I YKC E + + G+K S C K WS C +C I +G + + G
Sbjct: 61 ITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNQKSCPNPGEIRNGQID-VPGGILFG 119
Query: 433 ARALYSCRENFTLVGNPERTC---GDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKA 489
A +SC + L G+ C G W P C +CP PP + N +
Sbjct: 120 ATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHY 179
Query: 490 G--SLASYTCENGHILSGSTSVTCTLG---GAWSGVPPSCKYVNCGT---PTIHKGSFVL 541
G +Y C G + G S+ CT+ G WSG PP C+ + + PT+ K + V
Sbjct: 180 GYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTVQKPTTVN 239
Query: 542 INGT 545
+ T
Sbjct: 240 VPTT 243
Score = 75.4 bits (177), Expect = 1e-12
Identities = 57/201 (28%), Positives = 82/201 (40%), Gaps = 30/201 (14%)
Query: 591 PEVPSGG-YMEAFDYYVHST-INFHCEAGH-KLIGEPN-LVCQQDGEWSGDSPTCEYIDC 646
P+VP+ +E + T I + CE K+ GE + ++C + +WS C C
Sbjct: 40 PDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNQKSC 99
Query: 647 GKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCT---EEFQWSDSSPRCEE 703
+ G +++ G G+ I +SC T Y+L G C QWSD P C E
Sbjct: 100 PNPGEIRNGQIDVPGGIL-FGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECRE 158
Query: 704 IRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGES 763
I C P + I+ +R H Y V Y C KG+ +IGE
Sbjct: 159 IYCPAPPQIDNGIIQ---GERDH----------------YGYRQSVTYACNKGFTMIGEH 199
Query: 764 LSTC---EDNGQWSGTTPTCQ 781
C D G+WSG P C+
Sbjct: 200 SIYCTVNNDEGEWSGPPPECR 220
Score = 70.1 bits (164), Expect = 4e-11
Identities = 46/185 (24%), Positives = 77/185 (41%), Gaps = 11/185 (5%)
Query: 528 NCGTPTIHKGSFVLINGTTTY--GSIAQFTCEPDYWLNGAEE--LVCNRDGKWSYDIPSC 583
+CG P + + G T++ ++ + CE + E+ ++C + +WS C
Sbjct: 35 DCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFC 94
Query: 584 ELTSCPEP-EVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDG---EWSGDSP 639
SCP P E+ +G +TI+F C G+KL G + C G +WS P
Sbjct: 95 NQKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLP 154
Query: 640 TCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCT---EEFQWSD 696
C I C P + G ++ + Y+C + ++G CT +E +WS
Sbjct: 155 ECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSG 214
Query: 697 SSPRC 701
P C
Sbjct: 215 PPPEC 219
Score = 68.1 bits (159), Expect = 2e-10
Identities = 54/207 (26%), Positives = 82/207 (39%), Gaps = 31/207 (14%)
Query: 645 DCGKLPTLPYGTMELLNGTTHL--GSVIQYSCTTNYRLVGPVRRT--CTEEFQWSDSSPR 700
DCG P +P L G T +VI Y C ++ + + + C + QWSD
Sbjct: 35 DCGLPPDVP-NAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEF 93
Query: 701 CEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVI 760
C + C +P + V G GA + + C GYK+
Sbjct: 94 CNQKSCPNPGEIRNGQIDVPGG--------------------ILFGATISFSCNTGYKLF 133
Query: 761 GESLSTCEDNG---QWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENW 817
G + S C +G QWS P C+ + C P +I+NG + + Y + Y C++ +
Sbjct: 134 GSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGF 193
Query: 818 ELEGVIRRMCQEN---GTWSLEPPICK 841
+ G C N G WS PP C+
Sbjct: 194 TMIGEHSIYCTVNNDEGEWSGPPPECR 220
Score = 34.3 bits (75), Expect = 2.4
Identities = 17/60 (28%), Positives = 28/60 (46%), Gaps = 5/60 (8%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRG---DWTLEPPFC 58
C +P N ++ +P I+ G + C+ GY+LFG+ C + G W+ P C
Sbjct: 99 CPNPGEIRNGQIDVPG--GILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPEC 156
Score = 32.3 bits (70), Expect = 9.7
Identities = 16/59 (27%), Positives = 29/59 (49%), Gaps = 2/59 (3%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGY-ELFGARQRECTLRG-DWTLEPPFC 58
CG P PNA+ ++ + T+ Y+C+E + ++ G + L+G W+ FC
Sbjct: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFC 94
>AL445493-5|CAH70779.1| 181|Homo sapiens complement component 4
binding protein, beta protein.
Length = 181
Score = 87.0 bits (206), Expect = 3e-16
Identities = 43/158 (27%), Positives = 65/158 (41%), Gaps = 1/158 (0%)
Query: 471 CPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCG 530
CP+ P V N+ + L +Y C G+ L G ++ C W C+ +C
Sbjct: 23 CPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCP 82
Query: 531 TPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPE 590
P + G F +G F C Y L G+ C D W+ P C+ C
Sbjct: 83 DPVLVNGEF-SSSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDP 141
Query: 591 PEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVC 628
P P GY E ++ + STI+++CE + L+G C
Sbjct: 142 PGNPVHGYFEGNNFTLGSTISYYCEDRYYLVGVQEQQC 179
Score = 75.4 bits (177), Expect = 1e-12
Identities = 42/140 (30%), Positives = 58/140 (41%), Gaps = 2/140 (1%)
Query: 551 IAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFDYYVHSTI 610
+ + C Y L G + L CN +W C L CP+P + +G + + V I
Sbjct: 44 LGTYVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKI 103
Query: 611 NFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVI 670
F C + L G C +D W+ P C+ DC +G E N T LGS I
Sbjct: 104 TFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFT--LGSTI 161
Query: 671 QYSCTTNYRLVGPVRRTCTE 690
Y C Y LVG + C +
Sbjct: 162 SYYCEDRYYLVGVQEQQCVD 181
Score = 72.1 bits (169), Expect = 1e-11
Identities = 45/172 (26%), Positives = 73/172 (42%), Gaps = 6/172 (3%)
Query: 719 VTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTP 778
V+ +D H L ++ V L Y C KGY ++G+ C + +W TT
Sbjct: 15 VSASDAEHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKEWDNTTT 74
Query: 779 TCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPP 838
C+ C +P + NG+ + S + C++++ L+G R C E+ TW+ P
Sbjct: 75 ECRLGHCPDPVLV-NGEFS-SSGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFP 132
Query: 839 ICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCI 890
ICK C P + + ++G Y CE Y L G Q + C+
Sbjct: 133 ICKSRDCDPPGNPVHG----YFEGNNFTLGSTISYYCEDRYYLVGVQEQQCV 180
Score = 68.1 bits (159), Expect = 2e-10
Identities = 40/141 (28%), Positives = 60/141 (42%), Gaps = 6/141 (4%)
Query: 811 YQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGE 870
Y C + + L G C + W C+ CPDP +G + +++ +
Sbjct: 47 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLV----NGEFSSSGPVNVSDK 102
Query: 871 AHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSS 930
+ C Y LKG C+ W P+C DC PGN +G N TL GS+
Sbjct: 103 ITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFE-GNNFTL-GST 160
Query: 931 VEYYCLSQYQRVGPFLRKCLD 951
+ YYC +Y VG ++C+D
Sbjct: 161 ISYYCEDRYYLVGVQEQQCVD 181
Score = 65.3 bits (152), Expect = 1e-09
Identities = 39/136 (28%), Positives = 53/136 (38%), Gaps = 5/136 (3%)
Query: 437 YSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGSLASYT 496
Y C + + LVG C WD C CPDP V+ + ++
Sbjct: 47 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLVNGEFSSSGPVNVSDKITFM 106
Query: 497 CENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTP--TIHKGSFVLINGTTTYGSIAQF 554
C + +IL GS C W+ P CK +C P +H G F T GS +
Sbjct: 107 CNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVH-GYFE--GNNFTLGSTISY 163
Query: 555 TCEPDYWLNGAEELVC 570
CE Y+L G +E C
Sbjct: 164 YCEDRYYLVGVQEQQC 179
Score = 59.7 bits (138), Expect = 6e-08
Identities = 45/193 (23%), Positives = 71/193 (36%), Gaps = 23/193 (11%)
Query: 577 SYDIPSCELTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSG 636
++ + + + CPE A + + C G+ L+G+ L C EW
Sbjct: 12 AWRVSASDAEHCPELPPVDNSIFVAKEVEGQILGTYVCIKGYHLVGKKTLFCNASKEWDN 71
Query: 637 DSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSD 696
+ C C P L G +G ++ I + C +Y L G R C E+ W+
Sbjct: 72 TTTECRLGHCPD-PVLVNGEFSS-SGPVNVSDKITFMCNDHYILKGSNRSQCLEDHTWAP 129
Query: 697 SSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKG 756
P C+ C P GN HG+ GN + +G+ + Y CE
Sbjct: 130 PFPICKSRDCDPP-----------GNP-VHGYF---------EGNNFTLGSTISYYCEDR 168
Query: 757 YKVIGESLSTCED 769
Y ++G C D
Sbjct: 169 YYLVGVQEQQCVD 181
Score = 48.8 bits (111), Expect = 1e-04
Identities = 30/135 (22%), Positives = 48/135 (35%), Gaps = 2/135 (1%)
Query: 377 YKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRTTHGARAL 436
Y C +G+ L+G K+ C W C+ +C P+ +
Sbjct: 47 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCP--DPVLVNGEFSSSGPVNVSDKIT 104
Query: 437 YSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKAGSLASYT 496
+ C +++ L G+ C ++ W P C C P + N GS SY
Sbjct: 105 FMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCDPPGNPVHGYFEGNNFTLGSTISYY 164
Query: 497 CENGHILSGSTSVTC 511
CE+ + L G C
Sbjct: 165 CEDRYYLVGVQEQQC 179
Score = 48.4 bits (110), Expect = 1e-04
Identities = 26/91 (28%), Positives = 41/91 (45%), Gaps = 2/91 (2%)
Query: 873 YQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVE 932
Y C +GY+L G +T C + +W+ T C C P + NG+ S+G +
Sbjct: 47 YVCIKGYHLVGKKTLFCNASKEWDNTTTECRLGHCPDPVLV-NGEFS-SSGPVNVSDKIT 104
Query: 933 YYCLSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
+ C Y G +CL+D W+ P C+
Sbjct: 105 FMCNDHYILKGSNRSQCLEDHTWAPPFPICK 135
Score = 42.3 bits (95), Expect = 0.009
Identities = 24/86 (27%), Positives = 37/86 (43%), Gaps = 2/86 (2%)
Query: 370 DVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRT 429
+V +I + C + ++L G C +D W+ P CK +C P N
Sbjct: 98 NVSDKITFMCNDHYILKGSNRSQCLEDHTWAPPFPICKSRDCD--PPGNPVHGYFEGNNF 155
Query: 430 THGARALYSCRENFTLVGNPERTCGD 455
T G+ Y C + + LVG E+ C D
Sbjct: 156 TLGSTISYYCEDRYYLVGVQEQQCVD 181
>BC109190-1|AAI09191.1| 181|Homo sapiens CR1L protein protein.
Length = 181
Score = 85.4 bits (202), Expect = 1e-15
Identities = 54/183 (29%), Positives = 79/183 (43%), Gaps = 9/183 (4%)
Query: 503 LSGSTSVTCTLGGAWSGVPPSCKYVNCGTP--TIHKGSFVLINGTTTYGSIAQFTCEPDY 560
+ G + V C W PSC V C P +H + G ++CEP Y
Sbjct: 1 MKGPSHVKCQALNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGY 59
Query: 561 WLNGAEELVCNRDGKWSYDIPSCELTSCPE--PEVPSGGYMEAFDYYVHSTINFHCEAGH 618
L G+ L C G WS P CE+ SC + ++P+G + + + + ++F C+ G
Sbjct: 60 DLRGSTYLHCTPQGDWSPAAPRCEVKSCDDFLGQLPNGHVLFPLNLQLGAKVDFVCDEGF 119
Query: 619 KLIGEPNLVCQQDGE---WSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCT 675
+L G C G W P CE C + P +P M + H+GS I YSCT
Sbjct: 120 QLKGSSASYCVLAGMESLWDSSVPVCERKSC-ETPPVPVNGMVHVITDIHVGSRINYSCT 178
Query: 676 TNY 678
T +
Sbjct: 179 TGF 181
Score = 83.0 bits (196), Expect = 5e-15
Identities = 50/183 (27%), Positives = 78/183 (42%), Gaps = 8/183 (4%)
Query: 761 GESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFY-GATAFYQCDENWEL 819
G S C+ +W P+C V C P + + + T F G FY C+ ++L
Sbjct: 3 GPSHVKCQALNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDL 61
Query: 820 EGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGY 879
G C G WS P C+ +C D Q+ G L + L +G + + C+ G+
Sbjct: 62 RGSTYLHCTPQGDWSPAAPRCEVKSCDDFLGQLPNGHVLFPLN--LQLGAKVDFVCDEGF 119
Query: 880 NLKGHQTRTCISKGQ---WNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCL 936
LKG C+ G W+ +VPVC C +P NG + + + GS + Y C
Sbjct: 120 QLKGSSASYCVLAGMESLWDSSVPVCERKSCETPPVPVNGMVHVITDIHV-GSRINYSCT 178
Query: 937 SQY 939
+ +
Sbjct: 179 TGF 181
Score = 81.8 bits (193), Expect = 1e-14
Identities = 52/167 (31%), Positives = 69/167 (41%), Gaps = 9/167 (5%)
Query: 459 WDGEAPRCLFDWCPDPPAVSNASVTV---NGHKAGSLASYTCENGHILSGSTSVTCTLGG 515
W+ E P C C PP V +A T + G Y+CE G+ L GST + CT G
Sbjct: 15 WEPELPSCS-RVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGSTYLHCTPQG 73
Query: 516 AWSGVPPSCKYVNCGTPTIH-KGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVC---N 571
WS P C+ +C VL G+ F C+ + L G+ C
Sbjct: 74 DWSPAAPRCEVKSCDDFLGQLPNGHVLFPLNLQLGAKVDFVCDEGFQLKGSSASYCVLAG 133
Query: 572 RDGKWSYDIPSCELTSCPEPEVPSGGYMEAF-DYYVHSTINFHCEAG 617
+ W +P CE SC P VP G + D +V S IN+ C G
Sbjct: 134 MESLWDSSVPVCERKSCETPPVPVNGMVHVITDIHVGSRINYSCTTG 180
Score = 80.6 bits (190), Expect = 3e-14
Identities = 51/187 (27%), Positives = 79/187 (42%), Gaps = 14/187 (7%)
Query: 697 SSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKG 756
S +C+ + +P + S V D H R DN + G V Y CE G
Sbjct: 5 SHVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDN------FSPGQEVFYSCEPG 58
Query: 757 YKVIGESLSTCEDNGQWSGTTPTCQYVDCGN-PGRIENGKVTLPSNATFYGATAFYQCDE 815
Y + G + C G WS P C+ C + G++ NG V P N GA + CDE
Sbjct: 59 YDLRGSTYLHCTPQGDWSPAAPRCEVKSCDDFLGQLPNGHVLFPLNLQL-GAKVDFVCDE 117
Query: 816 NWELEGVIRRMCQENG---TWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAH 872
++L+G C G W P+C+ +C P + +G++ V + + +G +
Sbjct: 118 GFQLKGSSASYCVLAGMESLWDSSVPVCERKSCETPPVPV---NGMVHVITDIHVGSRIN 174
Query: 873 YQCERGY 879
Y C G+
Sbjct: 175 YSCTTGF 181
Score = 72.5 bits (170), Expect = 7e-12
Identities = 43/139 (30%), Positives = 59/139 (42%), Gaps = 6/139 (4%)
Query: 367 NDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGG-LTPIEDGDVALI 425
+++ G + Y C G+ L G HC G WS A P C+ +C L + +G V L
Sbjct: 43 DNFSPGQEVFYSCEPGYDLRGSTYLHCTPQGDWSPAAPRCEVKSCDDFLGQLPNGHV-LF 101
Query: 426 DNRTTHGARALYSCRENFTLVGNPERTC---GDEGIWDGEAPRCLFDWCPDPPAVSNASV 482
GA+ + C E F L G+ C G E +WD P C C PP N V
Sbjct: 102 PLNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWDSSVPVCERKSCETPPVPVNGMV 161
Query: 483 -TVNGHKAGSLASYTCENG 500
+ GS +Y+C G
Sbjct: 162 HVITDIHVGSRINYSCTTG 180
Score = 71.7 bits (168), Expect = 1e-11
Identities = 46/164 (28%), Positives = 66/164 (40%), Gaps = 7/164 (4%)
Query: 562 LNGAEELVCNRDGKWSYDIPSCELTSCPEPEV--PSGGYMEAFDYYVHSTINFHCEAGHK 619
+ G + C KW ++PSC P P+V + ++ + + CE G+
Sbjct: 1 MKGPSHVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYD 60
Query: 620 LIGEPNLVCQQDGEWSGDSPTCEYIDCGK-LPTLPYGTMELLNGTTHLGSVIQYSCTTNY 678
L G L C G+WS +P CE C L LP G + L LG+ + + C +
Sbjct: 61 LRGSTYLHCTPQGDWSPAAPRCEVKSCDDFLGQLPNGHV-LFPLNLQLGAKVDFVCDEGF 119
Query: 679 RLVGPVRRTCT---EEFQWSDSSPRCEEIRCSDPIVAEKSIVSV 719
+L G C E W S P CE C P V +V V
Sbjct: 120 QLKGSSASYCVLAGMESLWDSSVPVCERKSCETPPVPVNGMVHV 163
Score = 60.1 bits (139), Expect = 4e-08
Identities = 40/149 (26%), Positives = 56/149 (37%), Gaps = 7/149 (4%)
Query: 819 LEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERG 878
++G CQ W E P C + P P + S G E Y CE G
Sbjct: 1 MKGPSHVKCQALNKWEPELPSCSRVCQPPPD--VLHAERTQRDKDNFSPGQEVFYSCEPG 58
Query: 879 YNLKGHQTRTCISKGQWNGTVPVCIPIDCRS-PGNIENGKIVISNGSTLFGSSVEYYCLS 937
Y+L+G C +G W+ P C C G + NG ++ L G+ V++ C
Sbjct: 59 YDLRGSTYLHCTPQGDWSPAAPRCEVKSCDDFLGQLPNGHVLFPLNLQL-GAKVDFVCDE 117
Query: 938 QYQRVGPFLRKCLDDGR---WSGEEPSCE 963
+Q G C+ G W P CE
Sbjct: 118 GFQLKGSSASYCVLAGMESLWDSSVPVCE 146
Score = 39.9 bits (89), Expect = 0.049
Identities = 18/57 (31%), Positives = 28/57 (49%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C P +A + +++N G Y C+ GY+L G+ CT +GDW+ P C
Sbjct: 26 CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGSTYLHCTPQGDWSPAAPRC 82
Score = 35.1 bits (77), Expect = 1.4
Identities = 21/85 (24%), Positives = 33/85 (38%), Gaps = 2/85 (2%)
Query: 881 LKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLF-GSSVEYYCLSQY 939
+KG C + +W +P C + C+ P ++ + + + G V Y C Y
Sbjct: 1 MKGPSHVKCQALNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGY 59
Query: 940 QRVGPFLRKCLDDGRWSGEEPSCEL 964
G C G WS P CE+
Sbjct: 60 DLRGSTYLHCTPQGDWSPAAPRCEV 84
>X04481-1|CAA28169.1| 752|Homo sapiens protein ( Human mRNA for
complement component C2. ).
Length = 752
Score = 85.0 bits (201), Expect = 1e-15
Identities = 55/173 (31%), Positives = 71/173 (41%), Gaps = 10/173 (5%)
Query: 362 TTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWS--GAPPS-----CKYVNCGGL 414
T L + + GS + Y CP+G + SR CK G W GA S CK V C
Sbjct: 34 TFTLSHGWAPGSLLTYSCPQG-LYPSPASRLCKSSGQWQTPGATRSLSKAVCKPVRCPAP 92
Query: 415 TPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL--FDWCP 472
E+G G + C + F L G+P R C G+WDGE C CP
Sbjct: 93 VSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWDGETAVCDNGAGHCP 152
Query: 473 DPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCK 525
+P A T G Y C + +L+GS+ C G WSG P C+
Sbjct: 153 NPGISLGAVRTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNGVWSGTEPICR 205
Score = 77.4 bits (182), Expect = 3e-13
Identities = 50/182 (27%), Positives = 72/182 (39%), Gaps = 12/182 (6%)
Query: 471 CPDPPAVSNASVTVN-GHKAGSLASYTCENGHILSGSTSVTCTLGGAWS--GVPPS---- 523
CP +S + T++ G GSL +Y+C G + S C G W G S
Sbjct: 24 CPQNVNISGGTFTLSHGWAPGSLLTYSCPQG-LYPSPASRLCKSSGQWQTPGATRSLSKA 82
Query: 524 -CKYVNCGTP-TIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIP 581
CK V C P + G + G+ G F CE + L G+ C +G W +
Sbjct: 83 VCKPVRCPAPVSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWDGETA 142
Query: 582 SCELTS--CPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSP 639
C+ + CP P + G F + + + C + L G CQ +G WSG P
Sbjct: 143 VCDNGAGHCPNPGISLGAVRTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNGVWSGTEP 202
Query: 640 TC 641
C
Sbjct: 203 IC 204
Score = 77.4 bits (182), Expect = 3e-13
Identities = 56/189 (29%), Positives = 78/189 (41%), Gaps = 19/189 (10%)
Query: 785 CGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTW-------SLEP 837
C I G TL S+ G+ Y C + R+C+ +G W SL
Sbjct: 24 CPQNVNISGGTFTL-SHGWAPGSLLTYSCPQGL-YPSPASRLCKSSGQWQTPGATRSLSK 81
Query: 838 PICKEITCPDPSAQIKAGSGLLVVT-STLSIGGEAHYQCERGYNLKGHQTRTCISKGQWN 896
+CK + CP P + +G+ + +GG ++CE G+ L+G R C G W+
Sbjct: 82 AVCKPVRCPAP---VSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWD 138
Query: 897 GTVPVCI--PIDCRSPGNIENGKIVISNGSTL-FGSSVEYYCLSQYQRVGPFLRKCLDDG 953
G VC C +PG I G + G G V Y C S G R+C +G
Sbjct: 139 GETAVCDNGAGHCPNPG-ISLG--AVRTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNG 195
Query: 954 RWSGEEPSC 962
WSG EP C
Sbjct: 196 VWSGTEPIC 204
Score = 76.2 bits (179), Expect = 6e-13
Identities = 48/166 (28%), Positives = 70/166 (42%), Gaps = 14/166 (8%)
Query: 746 GALVKYRCEKGYKVIGESLSTCEDNGQWS--GTTPT-----CQYVDCGNPGRIENGKVTL 798
G+L+ Y C +G S C+ +GQW G T + C+ V C P ENG T
Sbjct: 44 GSLLTYSCPQGLYPSPAS-RLCKSSGQWQTPGATRSLSKAVCKPVRCPAPVSFENGIYTP 102
Query: 799 PSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEIT--CPDPSAQIKAGS 856
+ G ++C++ + L G R C+ NG W E +C CP+P +
Sbjct: 103 RLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWDGETAVCDNGAGHCPNPGISL---- 158
Query: 857 GLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVC 902
G + G + Y+C L G R C G W+GT P+C
Sbjct: 159 GAVRTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNGVWSGTEPIC 204
Score = 74.1 bits (174), Expect = 2e-12
Identities = 61/206 (29%), Positives = 81/206 (39%), Gaps = 32/206 (15%)
Query: 646 CGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQW-------SDSS 698
C + + GT L +G GS++ YSC P R C QW S S
Sbjct: 24 CPQNVNISGGTFTLSHGWAP-GSLLTYSCPQGL-YPSPASRLCKSSGQWQTPGATRSLSK 81
Query: 699 PRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYK 758
C+ +RC P+ E I + +G+ Y +G V + CE G+
Sbjct: 82 AVCKPVRCPAPVSFENGIYTPR------------------LGS-YPVGGNVSFECEDGFI 122
Query: 759 VIGESLSTCEDNGQWSGTTPTCQ--YVDCGNPGRIENGKVTLPSNATFYGATAFYQCDEN 816
+ G + C NG W G T C C NPG I G V +G Y+C N
Sbjct: 123 LRGSPVRQCRPNGMWDGETAVCDNGAGHCPNPG-ISLGAVRTGFRFG-HGDKVRYRCSSN 180
Query: 817 WELEGVIRRMCQENGTWSLEPPICKE 842
L G R CQ NG WS PIC++
Sbjct: 181 LVLTGSSERECQGNGVWSGTEPICRQ 206
Score = 73.7 bits (173), Expect = 3e-12
Identities = 49/166 (29%), Positives = 68/166 (40%), Gaps = 11/166 (6%)
Query: 332 WNDVGCNLDYLHWICQYLPPTCGSPDKLLN---TTILGNDYDVGSRIVYKCPEGHMLLGD 388
W G +C+ P C +P N T LG+ Y VG + ++C +G +L G
Sbjct: 70 WQTPGATRSLSKAVCK--PVRCPAPVSFENGIYTPRLGS-YPVGGNVSFECEDGFILRGS 126
Query: 389 KSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDN--RTTHGARALYSCRENFTLV 446
R C+ +G W G C N G P + + R HG + Y C N L
Sbjct: 127 PVRQCRPNGMWDGETAVCD--NGAGHCPNPGISLGAVRTGFRFGHGDKVRYRCSSNLVLT 184
Query: 447 GNPERTCGDEGIWDGEAPRCLFDWCPD-PPAVSNASVTVNGHKAGS 491
G+ ER C G+W G P C + D P V+ A T H G+
Sbjct: 185 GSSERECQGNGVWSGTEPICRQPYSYDFPEDVAPALGTSFSHMLGA 230
Score = 67.7 bits (158), Expect = 2e-10
Identities = 50/181 (27%), Positives = 75/181 (41%), Gaps = 15/181 (8%)
Query: 534 IHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKW-------SYDIPSCELT 586
I G+F L +G GS+ ++C + + A L C G+W S C+
Sbjct: 30 ISGGTFTLSHGWAP-GSLLTYSCPQGLYPSPASRL-CKSSGQWQTPGATRSLSKAVCKPV 87
Query: 587 SCPEP-EVPSGGYMEAFDYY-VHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYI 644
CP P +G Y Y V ++F CE G L G P C+ +G W G++ C+
Sbjct: 88 RCPAPVSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWDGETAVCDN- 146
Query: 645 DCGKLPT--LPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCE 702
G P + G + H G ++Y C++N L G R C WS + P C
Sbjct: 147 GAGHCPNPGISLGAVRTGFRFGH-GDKVRYRCSSNLVLTGSSERECQGNGVWSGTEPICR 205
Query: 703 E 703
+
Sbjct: 206 Q 206
Score = 53.2 bits (122), Expect = 5e-06
Identities = 34/137 (24%), Positives = 53/137 (38%), Gaps = 8/137 (5%)
Query: 844 TCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNG------ 897
+ P + G ++ + G Y C +G +R C S GQW
Sbjct: 20 SAPSCPQNVNISGGTFTLSHGWAPGSLLTYSCPQGL-YPSPASRLCKSSGQWQTPGATRS 78
Query: 898 -TVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWS 956
+ VC P+ C +P + ENG GS G +V + C + G +R+C +G W
Sbjct: 79 LSKAVCKPVRCPAPVSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWD 138
Query: 957 GEEPSCELATNEAVDSG 973
GE C+ + G
Sbjct: 139 GETAVCDNGAGHCPNPG 155
>L09708-1|AAB97607.1| 752|Homo sapiens complement component C2
protein.
Length = 752
Score = 85.0 bits (201), Expect = 1e-15
Identities = 55/173 (31%), Positives = 71/173 (41%), Gaps = 10/173 (5%)
Query: 362 TTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWS--GAPPS-----CKYVNCGGL 414
T L + + GS + Y CP+G + SR CK G W GA S CK V C
Sbjct: 34 TFTLSHGWAPGSLLTYSCPQG-LYPSPASRLCKSSGQWQTPGATRSLSKAVCKPVRCPAP 92
Query: 415 TPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL--FDWCP 472
E+G G + C + F L G+P R C G+WDGE C CP
Sbjct: 93 VSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWDGETAVCDNGAGHCP 152
Query: 473 DPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCK 525
+P A T G Y C + +L+GS+ C G WSG P C+
Sbjct: 153 NPGISLGAVRTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNGVWSGTEPICR 205
Score = 77.4 bits (182), Expect = 3e-13
Identities = 50/182 (27%), Positives = 72/182 (39%), Gaps = 12/182 (6%)
Query: 471 CPDPPAVSNASVTVN-GHKAGSLASYTCENGHILSGSTSVTCTLGGAWS--GVPPS---- 523
CP +S + T++ G GSL +Y+C G + S C G W G S
Sbjct: 24 CPQNVNISGGTFTLSHGWAPGSLLTYSCPQG-LYPSPASRLCKSSGQWQTPGATRSLSKA 82
Query: 524 -CKYVNCGTP-TIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIP 581
CK V C P + G + G+ G F CE + L G+ C +G W +
Sbjct: 83 VCKPVRCPAPVSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWDGETA 142
Query: 582 SCELTS--CPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSP 639
C+ + CP P + G F + + + C + L G CQ +G WSG P
Sbjct: 143 VCDNGAGHCPNPGISLGAVRTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNGVWSGTEP 202
Query: 640 TC 641
C
Sbjct: 203 IC 204
Score = 77.4 bits (182), Expect = 3e-13
Identities = 56/189 (29%), Positives = 78/189 (41%), Gaps = 19/189 (10%)
Query: 785 CGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTW-------SLEP 837
C I G TL S+ G+ Y C + R+C+ +G W SL
Sbjct: 24 CPQNVNISGGTFTL-SHGWAPGSLLTYSCPQGL-YPSPASRLCKSSGQWQTPGATRSLSK 81
Query: 838 PICKEITCPDPSAQIKAGSGLLVVT-STLSIGGEAHYQCERGYNLKGHQTRTCISKGQWN 896
+CK + CP P + +G+ + +GG ++CE G+ L+G R C G W+
Sbjct: 82 AVCKPVRCPAP---VSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWD 138
Query: 897 GTVPVCI--PIDCRSPGNIENGKIVISNGSTL-FGSSVEYYCLSQYQRVGPFLRKCLDDG 953
G VC C +PG I G + G G V Y C S G R+C +G
Sbjct: 139 GETAVCDNGAGHCPNPG-ISLG--AVRTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNG 195
Query: 954 RWSGEEPSC 962
WSG EP C
Sbjct: 196 VWSGTEPIC 204
Score = 76.2 bits (179), Expect = 6e-13
Identities = 48/166 (28%), Positives = 70/166 (42%), Gaps = 14/166 (8%)
Query: 746 GALVKYRCEKGYKVIGESLSTCEDNGQWS--GTTPT-----CQYVDCGNPGRIENGKVTL 798
G+L+ Y C +G S C+ +GQW G T + C+ V C P ENG T
Sbjct: 44 GSLLTYSCPQGLYPSPAS-RLCKSSGQWQTPGATRSLSKAVCKPVRCPAPVSFENGIYTP 102
Query: 799 PSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEIT--CPDPSAQIKAGS 856
+ G ++C++ + L G R C+ NG W E +C CP+P +
Sbjct: 103 RLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWDGETAVCDNGAGHCPNPGISL---- 158
Query: 857 GLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVC 902
G + G + Y+C L G R C G W+GT P+C
Sbjct: 159 GAVRTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNGVWSGTEPIC 204
Score = 74.1 bits (174), Expect = 2e-12
Identities = 61/206 (29%), Positives = 81/206 (39%), Gaps = 32/206 (15%)
Query: 646 CGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQW-------SDSS 698
C + + GT L +G GS++ YSC P R C QW S S
Sbjct: 24 CPQNVNISGGTFTLSHGWAP-GSLLTYSCPQGL-YPSPASRLCKSSGQWQTPGATRSLSK 81
Query: 699 PRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYK 758
C+ +RC P+ E I + +G+ Y +G V + CE G+
Sbjct: 82 AVCKPVRCPAPVSFENGIYTPR------------------LGS-YPVGGNVSFECEDGFI 122
Query: 759 VIGESLSTCEDNGQWSGTTPTCQ--YVDCGNPGRIENGKVTLPSNATFYGATAFYQCDEN 816
+ G + C NG W G T C C NPG I G V +G Y+C N
Sbjct: 123 LRGSPVRQCRPNGMWDGETAVCDNGAGHCPNPG-ISLGAVRTGFRFG-HGDKVRYRCSSN 180
Query: 817 WELEGVIRRMCQENGTWSLEPPICKE 842
L G R CQ NG WS PIC++
Sbjct: 181 LVLTGSSERECQGNGVWSGTEPICRQ 206
Score = 73.7 bits (173), Expect = 3e-12
Identities = 49/166 (29%), Positives = 68/166 (40%), Gaps = 11/166 (6%)
Query: 332 WNDVGCNLDYLHWICQYLPPTCGSPDKLLN---TTILGNDYDVGSRIVYKCPEGHMLLGD 388
W G +C+ P C +P N T LG+ Y VG + ++C +G +L G
Sbjct: 70 WQTPGATRSLSKAVCK--PVRCPAPVSFENGIYTPRLGS-YPVGGNVSFECEDGFILRGS 126
Query: 389 KSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDN--RTTHGARALYSCRENFTLV 446
R C+ +G W G C N G P + + R HG + Y C N L
Sbjct: 127 PVRQCRPNGMWDGETAVCD--NGAGHCPNPGISLGAVRTGFRFGHGDKVRYRCSSNLVLT 184
Query: 447 GNPERTCGDEGIWDGEAPRCLFDWCPD-PPAVSNASVTVNGHKAGS 491
G+ ER C G+W G P C + D P V+ A T H G+
Sbjct: 185 GSSERECQGNGVWSGTEPICRQPYSYDFPEDVAPALGTSFSHMLGA 230
Score = 67.7 bits (158), Expect = 2e-10
Identities = 50/181 (27%), Positives = 75/181 (41%), Gaps = 15/181 (8%)
Query: 534 IHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKW-------SYDIPSCELT 586
I G+F L +G GS+ ++C + + A L C G+W S C+
Sbjct: 30 ISGGTFTLSHGWAP-GSLLTYSCPQGLYPSPASRL-CKSSGQWQTPGATRSLSKAVCKPV 87
Query: 587 SCPEP-EVPSGGYMEAFDYY-VHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYI 644
CP P +G Y Y V ++F CE G L G P C+ +G W G++ C+
Sbjct: 88 RCPAPVSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWDGETAVCDN- 146
Query: 645 DCGKLPT--LPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCE 702
G P + G + H G ++Y C++N L G R C WS + P C
Sbjct: 147 GAGHCPNPGISLGAVRTGFRFGH-GDKVRYRCSSNLVLTGSSERECQGNGVWSGTEPICR 205
Query: 703 E 703
+
Sbjct: 206 Q 206
Score = 53.2 bits (122), Expect = 5e-06
Identities = 34/137 (24%), Positives = 53/137 (38%), Gaps = 8/137 (5%)
Query: 844 TCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNG------ 897
+ P + G ++ + G Y C +G +R C S GQW
Sbjct: 20 SAPSCPQNVNISGGTFTLSHGWAPGSLLTYSCPQGL-YPSPASRLCKSSGQWQTPGATRS 78
Query: 898 -TVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWS 956
+ VC P+ C +P + ENG GS G +V + C + G +R+C +G W
Sbjct: 79 LSKAVCKPVRCPAPVSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWD 138
Query: 957 GEEPSCELATNEAVDSG 973
GE C+ + G
Sbjct: 139 GETAVCDNGAGHCPNPG 155
>BX005143-4|CAM25860.1| 752|Homo sapiens complement component 2
protein.
Length = 752
Score = 85.0 bits (201), Expect = 1e-15
Identities = 55/173 (31%), Positives = 71/173 (41%), Gaps = 10/173 (5%)
Query: 362 TTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWS--GAPPS-----CKYVNCGGL 414
T L + + GS + Y CP+G + SR CK G W GA S CK V C
Sbjct: 34 TFTLSHGWAPGSLLTYSCPQG-LYPSPASRLCKSSGQWQTPGATRSLSKAVCKPVRCPAP 92
Query: 415 TPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL--FDWCP 472
E+G G + C + F L G+P R C G+WDGE C CP
Sbjct: 93 VSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWDGETAVCDNGAGHCP 152
Query: 473 DPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCK 525
+P A T G Y C + +L+GS+ C G WSG P C+
Sbjct: 153 NPGISLGAVRTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNGVWSGTEPICR 205
Score = 77.4 bits (182), Expect = 3e-13
Identities = 50/182 (27%), Positives = 72/182 (39%), Gaps = 12/182 (6%)
Query: 471 CPDPPAVSNASVTVN-GHKAGSLASYTCENGHILSGSTSVTCTLGGAWS--GVPPS---- 523
CP +S + T++ G GSL +Y+C G + S C G W G S
Sbjct: 24 CPQNVNISGGTFTLSHGWAPGSLLTYSCPQG-LYPSPASRLCKSSGQWQTPGATRSLSKA 82
Query: 524 -CKYVNCGTP-TIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIP 581
CK V C P + G + G+ G F CE + L G+ C +G W +
Sbjct: 83 VCKPVRCPAPVSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWDGETA 142
Query: 582 SCELTS--CPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSP 639
C+ + CP P + G F + + + C + L G CQ +G WSG P
Sbjct: 143 VCDNGAGHCPNPGISLGAVRTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNGVWSGTEP 202
Query: 640 TC 641
C
Sbjct: 203 IC 204
Score = 77.4 bits (182), Expect = 3e-13
Identities = 56/189 (29%), Positives = 78/189 (41%), Gaps = 19/189 (10%)
Query: 785 CGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTW-------SLEP 837
C I G TL S+ G+ Y C + R+C+ +G W SL
Sbjct: 24 CPQNVNISGGTFTL-SHGWAPGSLLTYSCPQGL-YPSPASRLCKSSGQWQTPGATRSLSK 81
Query: 838 PICKEITCPDPSAQIKAGSGLLVVT-STLSIGGEAHYQCERGYNLKGHQTRTCISKGQWN 896
+CK + CP P + +G+ + +GG ++CE G+ L+G R C G W+
Sbjct: 82 AVCKPVRCPAP---VSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWD 138
Query: 897 GTVPVCI--PIDCRSPGNIENGKIVISNGSTL-FGSSVEYYCLSQYQRVGPFLRKCLDDG 953
G VC C +PG I G + G G V Y C S G R+C +G
Sbjct: 139 GETAVCDNGAGHCPNPG-ISLG--AVRTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNG 195
Query: 954 RWSGEEPSC 962
WSG EP C
Sbjct: 196 VWSGTEPIC 204
Score = 76.2 bits (179), Expect = 6e-13
Identities = 48/166 (28%), Positives = 70/166 (42%), Gaps = 14/166 (8%)
Query: 746 GALVKYRCEKGYKVIGESLSTCEDNGQWS--GTTPT-----CQYVDCGNPGRIENGKVTL 798
G+L+ Y C +G S C+ +GQW G T + C+ V C P ENG T
Sbjct: 44 GSLLTYSCPQGLYPSPAS-RLCKSSGQWQTPGATRSLSKAVCKPVRCPAPVSFENGIYTP 102
Query: 799 PSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEIT--CPDPSAQIKAGS 856
+ G ++C++ + L G R C+ NG W E +C CP+P +
Sbjct: 103 RLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWDGETAVCDNGAGHCPNPGISL---- 158
Query: 857 GLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVC 902
G + G + Y+C L G R C G W+GT P+C
Sbjct: 159 GAVRTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNGVWSGTEPIC 204
Score = 74.1 bits (174), Expect = 2e-12
Identities = 61/206 (29%), Positives = 81/206 (39%), Gaps = 32/206 (15%)
Query: 646 CGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQW-------SDSS 698
C + + GT L +G GS++ YSC P R C QW S S
Sbjct: 24 CPQNVNISGGTFTLSHGWAP-GSLLTYSCPQGL-YPSPASRLCKSSGQWQTPGATRSLSK 81
Query: 699 PRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYK 758
C+ +RC P+ E I + +G+ Y +G V + CE G+
Sbjct: 82 AVCKPVRCPAPVSFENGIYTPR------------------LGS-YPVGGNVSFECEDGFI 122
Query: 759 VIGESLSTCEDNGQWSGTTPTCQ--YVDCGNPGRIENGKVTLPSNATFYGATAFYQCDEN 816
+ G + C NG W G T C C NPG I G V +G Y+C N
Sbjct: 123 LRGSPVRQCRPNGMWDGETAVCDNGAGHCPNPG-ISLGAVRTGFRFG-HGDKVRYRCSSN 180
Query: 817 WELEGVIRRMCQENGTWSLEPPICKE 842
L G R CQ NG WS PIC++
Sbjct: 181 LVLTGSSERECQGNGVWSGTEPICRQ 206
Score = 73.7 bits (173), Expect = 3e-12
Identities = 49/166 (29%), Positives = 68/166 (40%), Gaps = 11/166 (6%)
Query: 332 WNDVGCNLDYLHWICQYLPPTCGSPDKLLN---TTILGNDYDVGSRIVYKCPEGHMLLGD 388
W G +C+ P C +P N T LG+ Y VG + ++C +G +L G
Sbjct: 70 WQTPGATRSLSKAVCK--PVRCPAPVSFENGIYTPRLGS-YPVGGNVSFECEDGFILRGS 126
Query: 389 KSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDN--RTTHGARALYSCRENFTLV 446
R C+ +G W G C N G P + + R HG + Y C N L
Sbjct: 127 PVRQCRPNGMWDGETAVCD--NGAGHCPNPGISLGAVRTGFRFGHGDKVRYRCSSNLVLT 184
Query: 447 GNPERTCGDEGIWDGEAPRCLFDWCPD-PPAVSNASVTVNGHKAGS 491
G+ ER C G+W G P C + D P V+ A T H G+
Sbjct: 185 GSSERECQGNGVWSGTEPICRQPYSYDFPEDVAPALGTSFSHMLGA 230
Score = 67.7 bits (158), Expect = 2e-10
Identities = 50/181 (27%), Positives = 75/181 (41%), Gaps = 15/181 (8%)
Query: 534 IHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKW-------SYDIPSCELT 586
I G+F L +G GS+ ++C + + A L C G+W S C+
Sbjct: 30 ISGGTFTLSHGWAP-GSLLTYSCPQGLYPSPASRL-CKSSGQWQTPGATRSLSKAVCKPV 87
Query: 587 SCPEP-EVPSGGYMEAFDYY-VHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYI 644
CP P +G Y Y V ++F CE G L G P C+ +G W G++ C+
Sbjct: 88 RCPAPVSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWDGETAVCDN- 146
Query: 645 DCGKLPT--LPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCE 702
G P + G + H G ++Y C++N L G R C WS + P C
Sbjct: 147 GAGHCPNPGISLGAVRTGFRFGH-GDKVRYRCSSNLVLTGSSERECQGNGVWSGTEPICR 205
Query: 703 E 703
+
Sbjct: 206 Q 206
Score = 53.2 bits (122), Expect = 5e-06
Identities = 34/137 (24%), Positives = 53/137 (38%), Gaps = 8/137 (5%)
Query: 844 TCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNG------ 897
+ P + G ++ + G Y C +G +R C S GQW
Sbjct: 20 SAPSCPQNVNISGGTFTLSHGWAPGSLLTYSCPQGL-YPSPASRLCKSSGQWQTPGATRS 78
Query: 898 -TVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWS 956
+ VC P+ C +P + ENG GS G +V + C + G +R+C +G W
Sbjct: 79 LSKAVCKPVRCPAPVSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWD 138
Query: 957 GEEPSCELATNEAVDSG 973
GE C+ + G
Sbjct: 139 GETAVCDNGAGHCPNPG 155
>BC043484-1|AAH43484.1| 752|Homo sapiens complement component 2
protein.
Length = 752
Score = 85.0 bits (201), Expect = 1e-15
Identities = 55/173 (31%), Positives = 71/173 (41%), Gaps = 10/173 (5%)
Query: 362 TTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWS--GAPPS-----CKYVNCGGL 414
T L + + GS + Y CP+G + SR CK G W GA S CK V C
Sbjct: 34 TFTLSHGWAPGSLLTYSCPQG-LYPSPASRLCKSSGQWQTPGATRSLSKAVCKPVRCPAP 92
Query: 415 TPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL--FDWCP 472
E+G G + C + F L G+P R C G+WDGE C CP
Sbjct: 93 VSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWDGETAVCDNGAGHCP 152
Query: 473 DPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCK 525
+P A T G Y C + +L+GS+ C G WSG P C+
Sbjct: 153 NPGISLGAVRTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNGVWSGTEPICR 205
Score = 77.4 bits (182), Expect = 3e-13
Identities = 50/182 (27%), Positives = 72/182 (39%), Gaps = 12/182 (6%)
Query: 471 CPDPPAVSNASVTVN-GHKAGSLASYTCENGHILSGSTSVTCTLGGAWS--GVPPS---- 523
CP +S + T++ G GSL +Y+C G + S C G W G S
Sbjct: 24 CPQNVNISGGTFTLSHGWAPGSLLTYSCPQG-LYPSPASRLCKSSGQWQTPGATRSLSKA 82
Query: 524 -CKYVNCGTP-TIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIP 581
CK V C P + G + G+ G F CE + L G+ C +G W +
Sbjct: 83 VCKPVRCPAPVSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWDGETA 142
Query: 582 SCELTS--CPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSP 639
C+ + CP P + G F + + + C + L G CQ +G WSG P
Sbjct: 143 VCDNGAGHCPNPGISLGAVRTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNGVWSGTEP 202
Query: 640 TC 641
C
Sbjct: 203 IC 204
Score = 77.4 bits (182), Expect = 3e-13
Identities = 56/189 (29%), Positives = 78/189 (41%), Gaps = 19/189 (10%)
Query: 785 CGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTW-------SLEP 837
C I G TL S+ G+ Y C + R+C+ +G W SL
Sbjct: 24 CPQNVNISGGTFTL-SHGWAPGSLLTYSCPQGL-YPSPASRLCKSSGQWQTPGATRSLSK 81
Query: 838 PICKEITCPDPSAQIKAGSGLLVVT-STLSIGGEAHYQCERGYNLKGHQTRTCISKGQWN 896
+CK + CP P + +G+ + +GG ++CE G+ L+G R C G W+
Sbjct: 82 AVCKPVRCPAP---VSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWD 138
Query: 897 GTVPVCI--PIDCRSPGNIENGKIVISNGSTL-FGSSVEYYCLSQYQRVGPFLRKCLDDG 953
G VC C +PG I G + G G V Y C S G R+C +G
Sbjct: 139 GETAVCDNGAGHCPNPG-ISLG--AVRTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNG 195
Query: 954 RWSGEEPSC 962
WSG EP C
Sbjct: 196 VWSGTEPIC 204
Score = 76.2 bits (179), Expect = 6e-13
Identities = 48/166 (28%), Positives = 70/166 (42%), Gaps = 14/166 (8%)
Query: 746 GALVKYRCEKGYKVIGESLSTCEDNGQWS--GTTPT-----CQYVDCGNPGRIENGKVTL 798
G+L+ Y C +G S C+ +GQW G T + C+ V C P ENG T
Sbjct: 44 GSLLTYSCPQGLYPSPAS-RLCKSSGQWQTPGATRSLSKAVCKPVRCPAPVSFENGIYTP 102
Query: 799 PSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEIT--CPDPSAQIKAGS 856
+ G ++C++ + L G R C+ NG W E +C CP+P +
Sbjct: 103 RLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWDGETAVCDNGAGHCPNPGISL---- 158
Query: 857 GLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVC 902
G + G + Y+C L G R C G W+GT P+C
Sbjct: 159 GAVRTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNGVWSGTEPIC 204
Score = 74.1 bits (174), Expect = 2e-12
Identities = 61/206 (29%), Positives = 81/206 (39%), Gaps = 32/206 (15%)
Query: 646 CGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQW-------SDSS 698
C + + GT L +G GS++ YSC P R C QW S S
Sbjct: 24 CPQNVNISGGTFTLSHGWAP-GSLLTYSCPQGL-YPSPASRLCKSSGQWQTPGATRSLSK 81
Query: 699 PRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYK 758
C+ +RC P+ E I + +G+ Y +G V + CE G+
Sbjct: 82 AVCKPVRCPAPVSFENGIYTPR------------------LGS-YPVGGNVSFECEDGFI 122
Query: 759 VIGESLSTCEDNGQWSGTTPTCQ--YVDCGNPGRIENGKVTLPSNATFYGATAFYQCDEN 816
+ G + C NG W G T C C NPG I G V +G Y+C N
Sbjct: 123 LRGSPVRQCRPNGMWDGETAVCDNGAGHCPNPG-ISLGAVRTGFRFG-HGDKVRYRCSSN 180
Query: 817 WELEGVIRRMCQENGTWSLEPPICKE 842
L G R CQ NG WS PIC++
Sbjct: 181 LVLTGSSERECQGNGVWSGTEPICRQ 206
Score = 73.7 bits (173), Expect = 3e-12
Identities = 49/166 (29%), Positives = 68/166 (40%), Gaps = 11/166 (6%)
Query: 332 WNDVGCNLDYLHWICQYLPPTCGSPDKLLN---TTILGNDYDVGSRIVYKCPEGHMLLGD 388
W G +C+ P C +P N T LG+ Y VG + ++C +G +L G
Sbjct: 70 WQTPGATRSLSKAVCK--PVRCPAPVSFENGIYTPRLGS-YPVGGNVSFECEDGFILRGS 126
Query: 389 KSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDN--RTTHGARALYSCRENFTLV 446
R C+ +G W G C N G P + + R HG + Y C N L
Sbjct: 127 PVRQCRPNGMWDGETAVCD--NGAGHCPNPGISLGAVRTGFRFGHGDKVRYRCSSNLVLT 184
Query: 447 GNPERTCGDEGIWDGEAPRCLFDWCPD-PPAVSNASVTVNGHKAGS 491
G+ ER C G+W G P C + D P V+ A T H G+
Sbjct: 185 GSSERECQGNGVWSGTEPICRQPYSYDFPEDVAPALGTSFSHMLGA 230
Score = 67.7 bits (158), Expect = 2e-10
Identities = 50/181 (27%), Positives = 75/181 (41%), Gaps = 15/181 (8%)
Query: 534 IHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKW-------SYDIPSCELT 586
I G+F L +G GS+ ++C + + A L C G+W S C+
Sbjct: 30 ISGGTFTLSHGWAP-GSLLTYSCPQGLYPSPASRL-CKSSGQWQTPGATRSLSKAVCKPV 87
Query: 587 SCPEP-EVPSGGYMEAFDYY-VHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYI 644
CP P +G Y Y V ++F CE G L G P C+ +G W G++ C+
Sbjct: 88 RCPAPVSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWDGETAVCDN- 146
Query: 645 DCGKLPT--LPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCE 702
G P + G + H G ++Y C++N L G R C WS + P C
Sbjct: 147 GAGHCPNPGISLGAVRTGFRFGH-GDKVRYRCSSNLVLTGSSERECQGNGVWSGTEPICR 205
Query: 703 E 703
+
Sbjct: 206 Q 206
Score = 53.2 bits (122), Expect = 5e-06
Identities = 34/137 (24%), Positives = 53/137 (38%), Gaps = 8/137 (5%)
Query: 844 TCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNG------ 897
+ P + G ++ + G Y C +G +R C S GQW
Sbjct: 20 SAPSCPQNVNISGGTFTLSHGWAPGSLLTYSCPQGL-YPSPASRLCKSSGQWQTPGATRS 78
Query: 898 -TVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWS 956
+ VC P+ C +P + ENG GS G +V + C + G +R+C +G W
Sbjct: 79 LSKAVCKPVRCPAPVSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWD 138
Query: 957 GEEPSCELATNEAVDSG 973
GE C+ + G
Sbjct: 139 GETAVCDNGAGHCPNPG 155
>BC029781-1|AAH29781.1| 328|Homo sapiens C2 protein protein.
Length = 328
Score = 85.0 bits (201), Expect = 1e-15
Identities = 55/173 (31%), Positives = 71/173 (41%), Gaps = 10/173 (5%)
Query: 362 TTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWS--GAPPS-----CKYVNCGGL 414
T L + + GS + Y CP+G + SR CK G W GA S CK V C
Sbjct: 34 TFTLSHGWAPGSLLTYSCPQG-LYPSPASRLCKSSGQWQTPGATRSLSKAVCKPVRCPAP 92
Query: 415 TPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL--FDWCP 472
E+G G + C + F L G+P R C G+WDGE C CP
Sbjct: 93 VSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWDGETAVCDNGAGHCP 152
Query: 473 DPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCK 525
+P A T G Y C + +L+GS+ C G WSG P C+
Sbjct: 153 NPGISLGAVRTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNGVWSGTEPICR 205
Score = 77.4 bits (182), Expect = 3e-13
Identities = 50/182 (27%), Positives = 72/182 (39%), Gaps = 12/182 (6%)
Query: 471 CPDPPAVSNASVTVN-GHKAGSLASYTCENGHILSGSTSVTCTLGGAWS--GVPPS---- 523
CP +S + T++ G GSL +Y+C G + S C G W G S
Sbjct: 24 CPQNVNISGGTFTLSHGWAPGSLLTYSCPQG-LYPSPASRLCKSSGQWQTPGATRSLSKA 82
Query: 524 -CKYVNCGTP-TIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIP 581
CK V C P + G + G+ G F CE + L G+ C +G W +
Sbjct: 83 VCKPVRCPAPVSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWDGETA 142
Query: 582 SCELTS--CPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSP 639
C+ + CP P + G F + + + C + L G CQ +G WSG P
Sbjct: 143 VCDNGAGHCPNPGISLGAVRTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNGVWSGTEP 202
Query: 640 TC 641
C
Sbjct: 203 IC 204
Score = 77.4 bits (182), Expect = 3e-13
Identities = 56/189 (29%), Positives = 78/189 (41%), Gaps = 19/189 (10%)
Query: 785 CGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTW-------SLEP 837
C I G TL S+ G+ Y C + R+C+ +G W SL
Sbjct: 24 CPQNVNISGGTFTL-SHGWAPGSLLTYSCPQGL-YPSPASRLCKSSGQWQTPGATRSLSK 81
Query: 838 PICKEITCPDPSAQIKAGSGLLVVT-STLSIGGEAHYQCERGYNLKGHQTRTCISKGQWN 896
+CK + CP P + +G+ + +GG ++CE G+ L+G R C G W+
Sbjct: 82 AVCKPVRCPAP---VSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWD 138
Query: 897 GTVPVCI--PIDCRSPGNIENGKIVISNGSTL-FGSSVEYYCLSQYQRVGPFLRKCLDDG 953
G VC C +PG I G + G G V Y C S G R+C +G
Sbjct: 139 GETAVCDNGAGHCPNPG-ISLG--AVRTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNG 195
Query: 954 RWSGEEPSC 962
WSG EP C
Sbjct: 196 VWSGTEPIC 204
Score = 76.2 bits (179), Expect = 6e-13
Identities = 48/166 (28%), Positives = 70/166 (42%), Gaps = 14/166 (8%)
Query: 746 GALVKYRCEKGYKVIGESLSTCEDNGQWS--GTTPT-----CQYVDCGNPGRIENGKVTL 798
G+L+ Y C +G S C+ +GQW G T + C+ V C P ENG T
Sbjct: 44 GSLLTYSCPQGLYPSPAS-RLCKSSGQWQTPGATRSLSKAVCKPVRCPAPVSFENGIYTP 102
Query: 799 PSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEIT--CPDPSAQIKAGS 856
+ G ++C++ + L G R C+ NG W E +C CP+P +
Sbjct: 103 RLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWDGETAVCDNGAGHCPNPGISL---- 158
Query: 857 GLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVC 902
G + G + Y+C L G R C G W+GT P+C
Sbjct: 159 GAVRTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNGVWSGTEPIC 204
Score = 74.1 bits (174), Expect = 2e-12
Identities = 61/206 (29%), Positives = 81/206 (39%), Gaps = 32/206 (15%)
Query: 646 CGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQW-------SDSS 698
C + + GT L +G GS++ YSC P R C QW S S
Sbjct: 24 CPQNVNISGGTFTLSHGWAP-GSLLTYSCPQGL-YPSPASRLCKSSGQWQTPGATRSLSK 81
Query: 699 PRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYK 758
C+ +RC P+ E I + +G+ Y +G V + CE G+
Sbjct: 82 AVCKPVRCPAPVSFENGIYTPR------------------LGS-YPVGGNVSFECEDGFI 122
Query: 759 VIGESLSTCEDNGQWSGTTPTCQ--YVDCGNPGRIENGKVTLPSNATFYGATAFYQCDEN 816
+ G + C NG W G T C C NPG I G V +G Y+C N
Sbjct: 123 LRGSPVRQCRPNGMWDGETAVCDNGAGHCPNPG-ISLGAVRTGFRFG-HGDKVRYRCSSN 180
Query: 817 WELEGVIRRMCQENGTWSLEPPICKE 842
L G R CQ NG WS PIC++
Sbjct: 181 LVLTGSSERECQGNGVWSGTEPICRQ 206
Score = 73.7 bits (173), Expect = 3e-12
Identities = 49/166 (29%), Positives = 68/166 (40%), Gaps = 11/166 (6%)
Query: 332 WNDVGCNLDYLHWICQYLPPTCGSPDKLLN---TTILGNDYDVGSRIVYKCPEGHMLLGD 388
W G +C+ P C +P N T LG+ Y VG + ++C +G +L G
Sbjct: 70 WQTPGATRSLSKAVCK--PVRCPAPVSFENGIYTPRLGS-YPVGGNVSFECEDGFILRGS 126
Query: 389 KSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDN--RTTHGARALYSCRENFTLV 446
R C+ +G W G C N G P + + R HG + Y C N L
Sbjct: 127 PVRQCRPNGMWDGETAVCD--NGAGHCPNPGISLGAVRTGFRFGHGDKVRYRCSSNLVLT 184
Query: 447 GNPERTCGDEGIWDGEAPRCLFDWCPD-PPAVSNASVTVNGHKAGS 491
G+ ER C G+W G P C + D P V+ A T H G+
Sbjct: 185 GSSERECQGNGVWSGTEPICRQPYSYDFPEDVAPALGTSFSHMLGA 230
Score = 67.7 bits (158), Expect = 2e-10
Identities = 50/181 (27%), Positives = 75/181 (41%), Gaps = 15/181 (8%)
Query: 534 IHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKW-------SYDIPSCELT 586
I G+F L +G GS+ ++C + + A L C G+W S C+
Sbjct: 30 ISGGTFTLSHGWAP-GSLLTYSCPQGLYPSPASRL-CKSSGQWQTPGATRSLSKAVCKPV 87
Query: 587 SCPEP-EVPSGGYMEAFDYY-VHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYI 644
CP P +G Y Y V ++F CE G L G P C+ +G W G++ C+
Sbjct: 88 RCPAPVSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWDGETAVCDN- 146
Query: 645 DCGKLPT--LPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCE 702
G P + G + H G ++Y C++N L G R C WS + P C
Sbjct: 147 GAGHCPNPGISLGAVRTGFRFGH-GDKVRYRCSSNLVLTGSSERECQGNGVWSGTEPICR 205
Query: 703 E 703
+
Sbjct: 206 Q 206
Score = 53.2 bits (122), Expect = 5e-06
Identities = 34/137 (24%), Positives = 53/137 (38%), Gaps = 8/137 (5%)
Query: 844 TCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNG------ 897
+ P + G ++ + G Y C +G +R C S GQW
Sbjct: 20 SAPSCPQNVNISGGTFTLSHGWAPGSLLTYSCPQGL-YPSPASRLCKSSGQWQTPGATRS 78
Query: 898 -TVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWS 956
+ VC P+ C +P + ENG GS G +V + C + G +R+C +G W
Sbjct: 79 LSKAVCKPVRCPAPVSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWD 138
Query: 957 GEEPSCELATNEAVDSG 973
GE C+ + G
Sbjct: 139 GETAVCDNGAGHCPNPG 155
>BA000025-1|BAB63292.1| 577|Homo sapiens C2 protein.
Length = 577
Score = 85.0 bits (201), Expect = 1e-15
Identities = 55/173 (31%), Positives = 71/173 (41%), Gaps = 10/173 (5%)
Query: 362 TTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWS--GAPPS-----CKYVNCGGL 414
T L + + GS + Y CP+G + SR CK G W GA S CK V C
Sbjct: 34 TFTLSHGWAPGSLLTYSCPQG-LYPSPASRLCKSSGQWQTPGATRSLSKAVCKPVRCPAP 92
Query: 415 TPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL--FDWCP 472
E+G G + C + F L G+P R C G+WDGE C CP
Sbjct: 93 VSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWDGETAVCDNGAGHCP 152
Query: 473 DPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCK 525
+P A T G Y C + +L+GS+ C G WSG P C+
Sbjct: 153 NPGISLGAVRTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNGVWSGTEPICR 205
Score = 77.4 bits (182), Expect = 3e-13
Identities = 50/182 (27%), Positives = 72/182 (39%), Gaps = 12/182 (6%)
Query: 471 CPDPPAVSNASVTVN-GHKAGSLASYTCENGHILSGSTSVTCTLGGAWS--GVPPS---- 523
CP +S + T++ G GSL +Y+C G + S C G W G S
Sbjct: 24 CPQNVNISGGTFTLSHGWAPGSLLTYSCPQG-LYPSPASRLCKSSGQWQTPGATRSLSKA 82
Query: 524 -CKYVNCGTP-TIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIP 581
CK V C P + G + G+ G F CE + L G+ C +G W +
Sbjct: 83 VCKPVRCPAPVSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWDGETA 142
Query: 582 SCELTS--CPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSP 639
C+ + CP P + G F + + + C + L G CQ +G WSG P
Sbjct: 143 VCDNGAGHCPNPGISLGAVRTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNGVWSGTEP 202
Query: 640 TC 641
C
Sbjct: 203 IC 204
Score = 77.4 bits (182), Expect = 3e-13
Identities = 56/189 (29%), Positives = 78/189 (41%), Gaps = 19/189 (10%)
Query: 785 CGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTW-------SLEP 837
C I G TL S+ G+ Y C + R+C+ +G W SL
Sbjct: 24 CPQNVNISGGTFTL-SHGWAPGSLLTYSCPQGL-YPSPASRLCKSSGQWQTPGATRSLSK 81
Query: 838 PICKEITCPDPSAQIKAGSGLLVVT-STLSIGGEAHYQCERGYNLKGHQTRTCISKGQWN 896
+CK + CP P + +G+ + +GG ++CE G+ L+G R C G W+
Sbjct: 82 AVCKPVRCPAP---VSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWD 138
Query: 897 GTVPVCI--PIDCRSPGNIENGKIVISNGSTL-FGSSVEYYCLSQYQRVGPFLRKCLDDG 953
G VC C +PG I G + G G V Y C S G R+C +G
Sbjct: 139 GETAVCDNGAGHCPNPG-ISLG--AVRTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNG 195
Query: 954 RWSGEEPSC 962
WSG EP C
Sbjct: 196 VWSGTEPIC 204
Score = 76.2 bits (179), Expect = 6e-13
Identities = 48/166 (28%), Positives = 70/166 (42%), Gaps = 14/166 (8%)
Query: 746 GALVKYRCEKGYKVIGESLSTCEDNGQWS--GTTPT-----CQYVDCGNPGRIENGKVTL 798
G+L+ Y C +G S C+ +GQW G T + C+ V C P ENG T
Sbjct: 44 GSLLTYSCPQGLYPSPAS-RLCKSSGQWQTPGATRSLSKAVCKPVRCPAPVSFENGIYTP 102
Query: 799 PSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEIT--CPDPSAQIKAGS 856
+ G ++C++ + L G R C+ NG W E +C CP+P +
Sbjct: 103 RLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWDGETAVCDNGAGHCPNPGISL---- 158
Query: 857 GLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVC 902
G + G + Y+C L G R C G W+GT P+C
Sbjct: 159 GAVRTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNGVWSGTEPIC 204
Score = 74.1 bits (174), Expect = 2e-12
Identities = 61/206 (29%), Positives = 81/206 (39%), Gaps = 32/206 (15%)
Query: 646 CGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQW-------SDSS 698
C + + GT L +G GS++ YSC P R C QW S S
Sbjct: 24 CPQNVNISGGTFTLSHGWAP-GSLLTYSCPQGL-YPSPASRLCKSSGQWQTPGATRSLSK 81
Query: 699 PRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYK 758
C+ +RC P+ E I + +G+ Y +G V + CE G+
Sbjct: 82 AVCKPVRCPAPVSFENGIYTPR------------------LGS-YPVGGNVSFECEDGFI 122
Query: 759 VIGESLSTCEDNGQWSGTTPTCQ--YVDCGNPGRIENGKVTLPSNATFYGATAFYQCDEN 816
+ G + C NG W G T C C NPG I G V +G Y+C N
Sbjct: 123 LRGSPVRQCRPNGMWDGETAVCDNGAGHCPNPG-ISLGAVRTGFRFG-HGDKVRYRCSSN 180
Query: 817 WELEGVIRRMCQENGTWSLEPPICKE 842
L G R CQ NG WS PIC++
Sbjct: 181 LVLTGSSERECQGNGVWSGTEPICRQ 206
Score = 73.7 bits (173), Expect = 3e-12
Identities = 49/166 (29%), Positives = 68/166 (40%), Gaps = 11/166 (6%)
Query: 332 WNDVGCNLDYLHWICQYLPPTCGSPDKLLN---TTILGNDYDVGSRIVYKCPEGHMLLGD 388
W G +C+ P C +P N T LG+ Y VG + ++C +G +L G
Sbjct: 70 WQTPGATRSLSKAVCK--PVRCPAPVSFENGIYTPRLGS-YPVGGNVSFECEDGFILRGS 126
Query: 389 KSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDN--RTTHGARALYSCRENFTLV 446
R C+ +G W G C N G P + + R HG + Y C N L
Sbjct: 127 PVRQCRPNGMWDGETAVCD--NGAGHCPNPGISLGAVRTGFRFGHGDKVRYRCSSNLVLT 184
Query: 447 GNPERTCGDEGIWDGEAPRCLFDWCPD-PPAVSNASVTVNGHKAGS 491
G+ ER C G+W G P C + D P V+ A T H G+
Sbjct: 185 GSSERECQGNGVWSGTEPICRQPYSYDFPEDVAPALGTSFSHMLGA 230
Score = 67.7 bits (158), Expect = 2e-10
Identities = 50/181 (27%), Positives = 75/181 (41%), Gaps = 15/181 (8%)
Query: 534 IHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKW-------SYDIPSCELT 586
I G+F L +G GS+ ++C + + A L C G+W S C+
Sbjct: 30 ISGGTFTLSHGWAP-GSLLTYSCPQGLYPSPASRL-CKSSGQWQTPGATRSLSKAVCKPV 87
Query: 587 SCPEP-EVPSGGYMEAFDYY-VHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYI 644
CP P +G Y Y V ++F CE G L G P C+ +G W G++ C+
Sbjct: 88 RCPAPVSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWDGETAVCDN- 146
Query: 645 DCGKLPT--LPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCE 702
G P + G + H G ++Y C++N L G R C WS + P C
Sbjct: 147 GAGHCPNPGISLGAVRTGFRFGH-GDKVRYRCSSNLVLTGSSERECQGNGVWSGTEPICR 205
Query: 703 E 703
+
Sbjct: 206 Q 206
Score = 53.2 bits (122), Expect = 5e-06
Identities = 34/137 (24%), Positives = 53/137 (38%), Gaps = 8/137 (5%)
Query: 844 TCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNG------ 897
+ P + G ++ + G Y C +G +R C S GQW
Sbjct: 20 SAPSCPQNVNISGGTFTLSHGWAPGSLLTYSCPQGL-YPSPASRLCKSSGQWQTPGATRS 78
Query: 898 -TVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWS 956
+ VC P+ C +P + ENG GS G +V + C + G +R+C +G W
Sbjct: 79 LSKAVCKPVRCPAPVSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWD 138
Query: 957 GEEPSCELATNEAVDSG 973
GE C+ + G
Sbjct: 139 GETAVCDNGAGHCPNPG 155
>AY349611-1|AAQ15273.1| 752|Homo sapiens complement component 2
protein.
Length = 752
Score = 85.0 bits (201), Expect = 1e-15
Identities = 55/173 (31%), Positives = 71/173 (41%), Gaps = 10/173 (5%)
Query: 362 TTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWS--GAPPS-----CKYVNCGGL 414
T L + + GS + Y CP+G + SR CK G W GA S CK V C
Sbjct: 34 TFTLSHGWAPGSLLTYSCPQG-LYPSPASRLCKSSGQWQTPGATRSLSKAVCKPVRCPAP 92
Query: 415 TPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL--FDWCP 472
E+G G + C + F L G+P R C G+WDGE C CP
Sbjct: 93 VSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWDGETAVCDNGAGHCP 152
Query: 473 DPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCK 525
+P A T G Y C + +L+GS+ C G WSG P C+
Sbjct: 153 NPGISLGAVRTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNGVWSGTEPICR 205
Score = 77.4 bits (182), Expect = 3e-13
Identities = 50/182 (27%), Positives = 72/182 (39%), Gaps = 12/182 (6%)
Query: 471 CPDPPAVSNASVTVN-GHKAGSLASYTCENGHILSGSTSVTCTLGGAWS--GVPPS---- 523
CP +S + T++ G GSL +Y+C G + S C G W G S
Sbjct: 24 CPQNVNISGGTFTLSHGWAPGSLLTYSCPQG-LYPSPASRLCKSSGQWQTPGATRSLSKA 82
Query: 524 -CKYVNCGTP-TIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIP 581
CK V C P + G + G+ G F CE + L G+ C +G W +
Sbjct: 83 VCKPVRCPAPVSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWDGETA 142
Query: 582 SCELTS--CPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSP 639
C+ + CP P + G F + + + C + L G CQ +G WSG P
Sbjct: 143 VCDNGAGHCPNPGISLGAVRTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNGVWSGTEP 202
Query: 640 TC 641
C
Sbjct: 203 IC 204
Score = 77.4 bits (182), Expect = 3e-13
Identities = 56/189 (29%), Positives = 78/189 (41%), Gaps = 19/189 (10%)
Query: 785 CGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTW-------SLEP 837
C I G TL S+ G+ Y C + R+C+ +G W SL
Sbjct: 24 CPQNVNISGGTFTL-SHGWAPGSLLTYSCPQGL-YPSPASRLCKSSGQWQTPGATRSLSK 81
Query: 838 PICKEITCPDPSAQIKAGSGLLVVT-STLSIGGEAHYQCERGYNLKGHQTRTCISKGQWN 896
+CK + CP P + +G+ + +GG ++CE G+ L+G R C G W+
Sbjct: 82 AVCKPVRCPAP---VSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWD 138
Query: 897 GTVPVCI--PIDCRSPGNIENGKIVISNGSTL-FGSSVEYYCLSQYQRVGPFLRKCLDDG 953
G VC C +PG I G + G G V Y C S G R+C +G
Sbjct: 139 GETAVCDNGAGHCPNPG-ISLG--AVRTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNG 195
Query: 954 RWSGEEPSC 962
WSG EP C
Sbjct: 196 VWSGTEPIC 204
Score = 76.2 bits (179), Expect = 6e-13
Identities = 48/166 (28%), Positives = 70/166 (42%), Gaps = 14/166 (8%)
Query: 746 GALVKYRCEKGYKVIGESLSTCEDNGQWS--GTTPT-----CQYVDCGNPGRIENGKVTL 798
G+L+ Y C +G S C+ +GQW G T + C+ V C P ENG T
Sbjct: 44 GSLLTYSCPQGLYPSPAS-RLCKSSGQWQTPGATRSLSKAVCKPVRCPAPVSFENGIYTP 102
Query: 799 PSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEIT--CPDPSAQIKAGS 856
+ G ++C++ + L G R C+ NG W E +C CP+P +
Sbjct: 103 RLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWDGETAVCDNGAGHCPNPGISL---- 158
Query: 857 GLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVC 902
G + G + Y+C L G R C G W+GT P+C
Sbjct: 159 GAVRTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNGVWSGTEPIC 204
Score = 74.1 bits (174), Expect = 2e-12
Identities = 61/206 (29%), Positives = 81/206 (39%), Gaps = 32/206 (15%)
Query: 646 CGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQW-------SDSS 698
C + + GT L +G GS++ YSC P R C QW S S
Sbjct: 24 CPQNVNISGGTFTLSHGWAP-GSLLTYSCPQGL-YPSPASRLCKSSGQWQTPGATRSLSK 81
Query: 699 PRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYK 758
C+ +RC P+ E I + +G+ Y +G V + CE G+
Sbjct: 82 AVCKPVRCPAPVSFENGIYTPR------------------LGS-YPVGGNVSFECEDGFI 122
Query: 759 VIGESLSTCEDNGQWSGTTPTCQ--YVDCGNPGRIENGKVTLPSNATFYGATAFYQCDEN 816
+ G + C NG W G T C C NPG I G V +G Y+C N
Sbjct: 123 LRGSPVRQCRPNGMWDGETAVCDNGAGHCPNPG-ISLGAVRTGFRFG-HGDKVRYRCSSN 180
Query: 817 WELEGVIRRMCQENGTWSLEPPICKE 842
L G R CQ NG WS PIC++
Sbjct: 181 LVLTGSSERECQGNGVWSGTEPICRQ 206
Score = 73.7 bits (173), Expect = 3e-12
Identities = 49/166 (29%), Positives = 68/166 (40%), Gaps = 11/166 (6%)
Query: 332 WNDVGCNLDYLHWICQYLPPTCGSPDKLLN---TTILGNDYDVGSRIVYKCPEGHMLLGD 388
W G +C+ P C +P N T LG+ Y VG + ++C +G +L G
Sbjct: 70 WQTPGATRSLSKAVCK--PVRCPAPVSFENGIYTPRLGS-YPVGGNVSFECEDGFILRGS 126
Query: 389 KSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDN--RTTHGARALYSCRENFTLV 446
R C+ +G W G C N G P + + R HG + Y C N L
Sbjct: 127 PVRQCRPNGMWDGETAVCD--NGAGHCPNPGISLGAVRTGFRFGHGDKVRYRCSSNLVLT 184
Query: 447 GNPERTCGDEGIWDGEAPRCLFDWCPD-PPAVSNASVTVNGHKAGS 491
G+ ER C G+W G P C + D P V+ A T H G+
Sbjct: 185 GSSERECQGNGVWSGTEPICRQPYSYDFPEDVAPALGTSFSHMLGA 230
Score = 67.7 bits (158), Expect = 2e-10
Identities = 50/181 (27%), Positives = 75/181 (41%), Gaps = 15/181 (8%)
Query: 534 IHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKW-------SYDIPSCELT 586
I G+F L +G GS+ ++C + + A L C G+W S C+
Sbjct: 30 ISGGTFTLSHGWAP-GSLLTYSCPQGLYPSPASRL-CKSSGQWQTPGATRSLSKAVCKPV 87
Query: 587 SCPEP-EVPSGGYMEAFDYY-VHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYI 644
CP P +G Y Y V ++F CE G L G P C+ +G W G++ C+
Sbjct: 88 RCPAPVSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWDGETAVCDN- 146
Query: 645 DCGKLPT--LPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCE 702
G P + G + H G ++Y C++N L G R C WS + P C
Sbjct: 147 GAGHCPNPGISLGAVRTGFRFGH-GDKVRYRCSSNLVLTGSSERECQGNGVWSGTEPICR 205
Query: 703 E 703
+
Sbjct: 206 Q 206
Score = 53.2 bits (122), Expect = 5e-06
Identities = 34/137 (24%), Positives = 53/137 (38%), Gaps = 8/137 (5%)
Query: 844 TCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNG------ 897
+ P + G ++ + G Y C +G +R C S GQW
Sbjct: 20 SAPSCPQNVNISGGTFTLSHGWAPGSLLTYSCPQGL-YPSPASRLCKSSGQWQTPGATRS 78
Query: 898 -TVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWS 956
+ VC P+ C +P + ENG GS G +V + C + G +R+C +G W
Sbjct: 79 LSKAVCKPVRCPAPVSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWD 138
Query: 957 GEEPSCELATNEAVDSG 973
GE C+ + G
Sbjct: 139 GETAVCDNGAGHCPNPG 155
>AL844853-9|CAI41858.1| 752|Homo sapiens complement component 2
protein.
Length = 752
Score = 85.0 bits (201), Expect = 1e-15
Identities = 55/173 (31%), Positives = 71/173 (41%), Gaps = 10/173 (5%)
Query: 362 TTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWS--GAPPS-----CKYVNCGGL 414
T L + + GS + Y CP+G + SR CK G W GA S CK V C
Sbjct: 34 TFTLSHGWAPGSLLTYSCPQG-LYPSPASRLCKSSGQWQTPGATRSLSKAVCKPVRCPAP 92
Query: 415 TPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL--FDWCP 472
E+G G + C + F L G+P R C G+WDGE C CP
Sbjct: 93 VSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWDGETAVCDNGAGHCP 152
Query: 473 DPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCK 525
+P A T G Y C + +L+GS+ C G WSG P C+
Sbjct: 153 NPGISLGAVRTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNGVWSGTEPICR 205
Score = 77.4 bits (182), Expect = 3e-13
Identities = 50/182 (27%), Positives = 72/182 (39%), Gaps = 12/182 (6%)
Query: 471 CPDPPAVSNASVTVN-GHKAGSLASYTCENGHILSGSTSVTCTLGGAWS--GVPPS---- 523
CP +S + T++ G GSL +Y+C G + S C G W G S
Sbjct: 24 CPQNVNISGGTFTLSHGWAPGSLLTYSCPQG-LYPSPASRLCKSSGQWQTPGATRSLSKA 82
Query: 524 -CKYVNCGTP-TIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIP 581
CK V C P + G + G+ G F CE + L G+ C +G W +
Sbjct: 83 VCKPVRCPAPVSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWDGETA 142
Query: 582 SCELTS--CPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSP 639
C+ + CP P + G F + + + C + L G CQ +G WSG P
Sbjct: 143 VCDNGAGHCPNPGISLGAVRTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNGVWSGTEP 202
Query: 640 TC 641
C
Sbjct: 203 IC 204
Score = 77.4 bits (182), Expect = 3e-13
Identities = 56/189 (29%), Positives = 78/189 (41%), Gaps = 19/189 (10%)
Query: 785 CGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTW-------SLEP 837
C I G TL S+ G+ Y C + R+C+ +G W SL
Sbjct: 24 CPQNVNISGGTFTL-SHGWAPGSLLTYSCPQGL-YPSPASRLCKSSGQWQTPGATRSLSK 81
Query: 838 PICKEITCPDPSAQIKAGSGLLVVT-STLSIGGEAHYQCERGYNLKGHQTRTCISKGQWN 896
+CK + CP P + +G+ + +GG ++CE G+ L+G R C G W+
Sbjct: 82 AVCKPVRCPAP---VSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWD 138
Query: 897 GTVPVCI--PIDCRSPGNIENGKIVISNGSTL-FGSSVEYYCLSQYQRVGPFLRKCLDDG 953
G VC C +PG I G + G G V Y C S G R+C +G
Sbjct: 139 GETAVCDNGAGHCPNPG-ISLG--AVRTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNG 195
Query: 954 RWSGEEPSC 962
WSG EP C
Sbjct: 196 VWSGTEPIC 204
Score = 76.2 bits (179), Expect = 6e-13
Identities = 48/166 (28%), Positives = 70/166 (42%), Gaps = 14/166 (8%)
Query: 746 GALVKYRCEKGYKVIGESLSTCEDNGQWS--GTTPT-----CQYVDCGNPGRIENGKVTL 798
G+L+ Y C +G S C+ +GQW G T + C+ V C P ENG T
Sbjct: 44 GSLLTYSCPQGLYPSPAS-RLCKSSGQWQTPGATRSLSKAVCKPVRCPAPVSFENGIYTP 102
Query: 799 PSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEIT--CPDPSAQIKAGS 856
+ G ++C++ + L G R C+ NG W E +C CP+P +
Sbjct: 103 RLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWDGETAVCDNGAGHCPNPGISL---- 158
Query: 857 GLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVC 902
G + G + Y+C L G R C G W+GT P+C
Sbjct: 159 GAVRTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNGVWSGTEPIC 204
Score = 74.1 bits (174), Expect = 2e-12
Identities = 61/206 (29%), Positives = 81/206 (39%), Gaps = 32/206 (15%)
Query: 646 CGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQW-------SDSS 698
C + + GT L +G GS++ YSC P R C QW S S
Sbjct: 24 CPQNVNISGGTFTLSHGWAP-GSLLTYSCPQGL-YPSPASRLCKSSGQWQTPGATRSLSK 81
Query: 699 PRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYK 758
C+ +RC P+ E I + +G+ Y +G V + CE G+
Sbjct: 82 AVCKPVRCPAPVSFENGIYTPR------------------LGS-YPVGGNVSFECEDGFI 122
Query: 759 VIGESLSTCEDNGQWSGTTPTCQ--YVDCGNPGRIENGKVTLPSNATFYGATAFYQCDEN 816
+ G + C NG W G T C C NPG I G V +G Y+C N
Sbjct: 123 LRGSPVRQCRPNGMWDGETAVCDNGAGHCPNPG-ISLGAVRTGFRFG-HGDKVRYRCSSN 180
Query: 817 WELEGVIRRMCQENGTWSLEPPICKE 842
L G R CQ NG WS PIC++
Sbjct: 181 LVLTGSSERECQGNGVWSGTEPICRQ 206
Score = 73.7 bits (173), Expect = 3e-12
Identities = 49/166 (29%), Positives = 68/166 (40%), Gaps = 11/166 (6%)
Query: 332 WNDVGCNLDYLHWICQYLPPTCGSPDKLLN---TTILGNDYDVGSRIVYKCPEGHMLLGD 388
W G +C+ P C +P N T LG+ Y VG + ++C +G +L G
Sbjct: 70 WQTPGATRSLSKAVCK--PVRCPAPVSFENGIYTPRLGS-YPVGGNVSFECEDGFILRGS 126
Query: 389 KSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDN--RTTHGARALYSCRENFTLV 446
R C+ +G W G C N G P + + R HG + Y C N L
Sbjct: 127 PVRQCRPNGMWDGETAVCD--NGAGHCPNPGISLGAVRTGFRFGHGDKVRYRCSSNLVLT 184
Query: 447 GNPERTCGDEGIWDGEAPRCLFDWCPD-PPAVSNASVTVNGHKAGS 491
G+ ER C G+W G P C + D P V+ A T H G+
Sbjct: 185 GSSERECQGNGVWSGTEPICRQPYSYDFPEDVAPALGTSFSHMLGA 230
Score = 67.7 bits (158), Expect = 2e-10
Identities = 50/181 (27%), Positives = 75/181 (41%), Gaps = 15/181 (8%)
Query: 534 IHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKW-------SYDIPSCELT 586
I G+F L +G GS+ ++C + + A L C G+W S C+
Sbjct: 30 ISGGTFTLSHGWAP-GSLLTYSCPQGLYPSPASRL-CKSSGQWQTPGATRSLSKAVCKPV 87
Query: 587 SCPEP-EVPSGGYMEAFDYY-VHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYI 644
CP P +G Y Y V ++F CE G L G P C+ +G W G++ C+
Sbjct: 88 RCPAPVSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWDGETAVCDN- 146
Query: 645 DCGKLPT--LPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCE 702
G P + G + H G ++Y C++N L G R C WS + P C
Sbjct: 147 GAGHCPNPGISLGAVRTGFRFGH-GDKVRYRCSSNLVLTGSSERECQGNGVWSGTEPICR 205
Query: 703 E 703
+
Sbjct: 206 Q 206
Score = 53.2 bits (122), Expect = 5e-06
Identities = 34/137 (24%), Positives = 53/137 (38%), Gaps = 8/137 (5%)
Query: 844 TCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNG------ 897
+ P + G ++ + G Y C +G +R C S GQW
Sbjct: 20 SAPSCPQNVNISGGTFTLSHGWAPGSLLTYSCPQGL-YPSPASRLCKSSGQWQTPGATRS 78
Query: 898 -TVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWS 956
+ VC P+ C +P + ENG GS G +V + C + G +R+C +G W
Sbjct: 79 LSKAVCKPVRCPAPVSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWD 138
Query: 957 GEEPSCELATNEAVDSG 973
GE C+ + G
Sbjct: 139 GETAVCDNGAGHCPNPG 155
>AL844853-8|CAI41857.1| 328|Homo sapiens complement component 2
protein.
Length = 328
Score = 85.0 bits (201), Expect = 1e-15
Identities = 55/173 (31%), Positives = 71/173 (41%), Gaps = 10/173 (5%)
Query: 362 TTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWS--GAPPS-----CKYVNCGGL 414
T L + + GS + Y CP+G + SR CK G W GA S CK V C
Sbjct: 34 TFTLSHGWAPGSLLTYSCPQG-LYPSPASRLCKSSGQWQTPGATRSLSKAVCKPVRCPAP 92
Query: 415 TPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL--FDWCP 472
E+G G + C + F L G+P R C G+WDGE C CP
Sbjct: 93 VSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWDGETAVCDNGAGHCP 152
Query: 473 DPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCK 525
+P A T G Y C + +L+GS+ C G WSG P C+
Sbjct: 153 NPGISLGAVRTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNGVWSGTEPICR 205
Score = 77.4 bits (182), Expect = 3e-13
Identities = 50/182 (27%), Positives = 72/182 (39%), Gaps = 12/182 (6%)
Query: 471 CPDPPAVSNASVTVN-GHKAGSLASYTCENGHILSGSTSVTCTLGGAWS--GVPPS---- 523
CP +S + T++ G GSL +Y+C G + S C G W G S
Sbjct: 24 CPQNVNISGGTFTLSHGWAPGSLLTYSCPQG-LYPSPASRLCKSSGQWQTPGATRSLSKA 82
Query: 524 -CKYVNCGTP-TIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIP 581
CK V C P + G + G+ G F CE + L G+ C +G W +
Sbjct: 83 VCKPVRCPAPVSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWDGETA 142
Query: 582 SCELTS--CPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSP 639
C+ + CP P + G F + + + C + L G CQ +G WSG P
Sbjct: 143 VCDNGAGHCPNPGISLGAVRTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNGVWSGTEP 202
Query: 640 TC 641
C
Sbjct: 203 IC 204
Score = 77.4 bits (182), Expect = 3e-13
Identities = 56/189 (29%), Positives = 78/189 (41%), Gaps = 19/189 (10%)
Query: 785 CGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTW-------SLEP 837
C I G TL S+ G+ Y C + R+C+ +G W SL
Sbjct: 24 CPQNVNISGGTFTL-SHGWAPGSLLTYSCPQGL-YPSPASRLCKSSGQWQTPGATRSLSK 81
Query: 838 PICKEITCPDPSAQIKAGSGLLVVT-STLSIGGEAHYQCERGYNLKGHQTRTCISKGQWN 896
+CK + CP P + +G+ + +GG ++CE G+ L+G R C G W+
Sbjct: 82 AVCKPVRCPAP---VSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWD 138
Query: 897 GTVPVCI--PIDCRSPGNIENGKIVISNGSTL-FGSSVEYYCLSQYQRVGPFLRKCLDDG 953
G VC C +PG I G + G G V Y C S G R+C +G
Sbjct: 139 GETAVCDNGAGHCPNPG-ISLG--AVRTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNG 195
Query: 954 RWSGEEPSC 962
WSG EP C
Sbjct: 196 VWSGTEPIC 204
Score = 76.2 bits (179), Expect = 6e-13
Identities = 48/166 (28%), Positives = 70/166 (42%), Gaps = 14/166 (8%)
Query: 746 GALVKYRCEKGYKVIGESLSTCEDNGQWS--GTTPT-----CQYVDCGNPGRIENGKVTL 798
G+L+ Y C +G S C+ +GQW G T + C+ V C P ENG T
Sbjct: 44 GSLLTYSCPQGLYPSPAS-RLCKSSGQWQTPGATRSLSKAVCKPVRCPAPVSFENGIYTP 102
Query: 799 PSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEIT--CPDPSAQIKAGS 856
+ G ++C++ + L G R C+ NG W E +C CP+P +
Sbjct: 103 RLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWDGETAVCDNGAGHCPNPGISL---- 158
Query: 857 GLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVC 902
G + G + Y+C L G R C G W+GT P+C
Sbjct: 159 GAVRTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNGVWSGTEPIC 204
Score = 74.1 bits (174), Expect = 2e-12
Identities = 61/206 (29%), Positives = 81/206 (39%), Gaps = 32/206 (15%)
Query: 646 CGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQW-------SDSS 698
C + + GT L +G GS++ YSC P R C QW S S
Sbjct: 24 CPQNVNISGGTFTLSHGWAP-GSLLTYSCPQGL-YPSPASRLCKSSGQWQTPGATRSLSK 81
Query: 699 PRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYK 758
C+ +RC P+ E I + +G+ Y +G V + CE G+
Sbjct: 82 AVCKPVRCPAPVSFENGIYTPR------------------LGS-YPVGGNVSFECEDGFI 122
Query: 759 VIGESLSTCEDNGQWSGTTPTCQ--YVDCGNPGRIENGKVTLPSNATFYGATAFYQCDEN 816
+ G + C NG W G T C C NPG I G V +G Y+C N
Sbjct: 123 LRGSPVRQCRPNGMWDGETAVCDNGAGHCPNPG-ISLGAVRTGFRFG-HGDKVRYRCSSN 180
Query: 817 WELEGVIRRMCQENGTWSLEPPICKE 842
L G R CQ NG WS PIC++
Sbjct: 181 LVLTGSSERECQGNGVWSGTEPICRQ 206
Score = 73.7 bits (173), Expect = 3e-12
Identities = 49/166 (29%), Positives = 68/166 (40%), Gaps = 11/166 (6%)
Query: 332 WNDVGCNLDYLHWICQYLPPTCGSPDKLLN---TTILGNDYDVGSRIVYKCPEGHMLLGD 388
W G +C+ P C +P N T LG+ Y VG + ++C +G +L G
Sbjct: 70 WQTPGATRSLSKAVCK--PVRCPAPVSFENGIYTPRLGS-YPVGGNVSFECEDGFILRGS 126
Query: 389 KSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDN--RTTHGARALYSCRENFTLV 446
R C+ +G W G C N G P + + R HG + Y C N L
Sbjct: 127 PVRQCRPNGMWDGETAVCD--NGAGHCPNPGISLGAVRTGFRFGHGDKVRYRCSSNLVLT 184
Query: 447 GNPERTCGDEGIWDGEAPRCLFDWCPD-PPAVSNASVTVNGHKAGS 491
G+ ER C G+W G P C + D P V+ A T H G+
Sbjct: 185 GSSERECQGNGVWSGTEPICRQPYSYDFPEDVAPALGTSFSHMLGA 230
Score = 67.7 bits (158), Expect = 2e-10
Identities = 50/181 (27%), Positives = 75/181 (41%), Gaps = 15/181 (8%)
Query: 534 IHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKW-------SYDIPSCELT 586
I G+F L +G GS+ ++C + + A L C G+W S C+
Sbjct: 30 ISGGTFTLSHGWAP-GSLLTYSCPQGLYPSPASRL-CKSSGQWQTPGATRSLSKAVCKPV 87
Query: 587 SCPEP-EVPSGGYMEAFDYY-VHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYI 644
CP P +G Y Y V ++F CE G L G P C+ +G W G++ C+
Sbjct: 88 RCPAPVSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWDGETAVCDN- 146
Query: 645 DCGKLPT--LPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCE 702
G P + G + H G ++Y C++N L G R C WS + P C
Sbjct: 147 GAGHCPNPGISLGAVRTGFRFGH-GDKVRYRCSSNLVLTGSSERECQGNGVWSGTEPICR 205
Query: 703 E 703
+
Sbjct: 206 Q 206
Score = 53.2 bits (122), Expect = 5e-06
Identities = 34/137 (24%), Positives = 53/137 (38%), Gaps = 8/137 (5%)
Query: 844 TCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNG------ 897
+ P + G ++ + G Y C +G +R C S GQW
Sbjct: 20 SAPSCPQNVNISGGTFTLSHGWAPGSLLTYSCPQGL-YPSPASRLCKSSGQWQTPGATRS 78
Query: 898 -TVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWS 956
+ VC P+ C +P + ENG GS G +V + C + G +R+C +G W
Sbjct: 79 LSKAVCKPVRCPAPVSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWD 138
Query: 957 GEEPSCELATNEAVDSG 973
GE C+ + G
Sbjct: 139 GETAVCDNGAGHCPNPG 155
>AL662849-4|CAI17451.1| 752|Homo sapiens complement component 2
protein.
Length = 752
Score = 85.0 bits (201), Expect = 1e-15
Identities = 55/173 (31%), Positives = 71/173 (41%), Gaps = 10/173 (5%)
Query: 362 TTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWS--GAPPS-----CKYVNCGGL 414
T L + + GS + Y CP+G + SR CK G W GA S CK V C
Sbjct: 34 TFTLSHGWAPGSLLTYSCPQG-LYPSPASRLCKSSGQWQTPGATRSLSKAVCKPVRCPAP 92
Query: 415 TPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL--FDWCP 472
E+G G + C + F L G+P R C G+WDGE C CP
Sbjct: 93 VSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWDGETAVCDNGAGHCP 152
Query: 473 DPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCK 525
+P A T G Y C + +L+GS+ C G WSG P C+
Sbjct: 153 NPGISLGAVRTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNGVWSGTEPICR 205
Score = 77.4 bits (182), Expect = 3e-13
Identities = 50/182 (27%), Positives = 72/182 (39%), Gaps = 12/182 (6%)
Query: 471 CPDPPAVSNASVTVN-GHKAGSLASYTCENGHILSGSTSVTCTLGGAWS--GVPPS---- 523
CP +S + T++ G GSL +Y+C G + S C G W G S
Sbjct: 24 CPQNVNISGGTFTLSHGWAPGSLLTYSCPQG-LYPSPASRLCKSSGQWQTPGATRSLSKA 82
Query: 524 -CKYVNCGTP-TIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIP 581
CK V C P + G + G+ G F CE + L G+ C +G W +
Sbjct: 83 VCKPVRCPAPVSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWDGETA 142
Query: 582 SCELTS--CPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSP 639
C+ + CP P + G F + + + C + L G CQ +G WSG P
Sbjct: 143 VCDNGAGHCPNPGISLGAVRTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNGVWSGTEP 202
Query: 640 TC 641
C
Sbjct: 203 IC 204
Score = 77.4 bits (182), Expect = 3e-13
Identities = 56/189 (29%), Positives = 78/189 (41%), Gaps = 19/189 (10%)
Query: 785 CGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTW-------SLEP 837
C I G TL S+ G+ Y C + R+C+ +G W SL
Sbjct: 24 CPQNVNISGGTFTL-SHGWAPGSLLTYSCPQGL-YPSPASRLCKSSGQWQTPGATRSLSK 81
Query: 838 PICKEITCPDPSAQIKAGSGLLVVT-STLSIGGEAHYQCERGYNLKGHQTRTCISKGQWN 896
+CK + CP P + +G+ + +GG ++CE G+ L+G R C G W+
Sbjct: 82 AVCKPVRCPAP---VSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWD 138
Query: 897 GTVPVCI--PIDCRSPGNIENGKIVISNGSTL-FGSSVEYYCLSQYQRVGPFLRKCLDDG 953
G VC C +PG I G + G G V Y C S G R+C +G
Sbjct: 139 GETAVCDNGAGHCPNPG-ISLG--AVRTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNG 195
Query: 954 RWSGEEPSC 962
WSG EP C
Sbjct: 196 VWSGTEPIC 204
Score = 76.2 bits (179), Expect = 6e-13
Identities = 48/166 (28%), Positives = 70/166 (42%), Gaps = 14/166 (8%)
Query: 746 GALVKYRCEKGYKVIGESLSTCEDNGQWS--GTTPT-----CQYVDCGNPGRIENGKVTL 798
G+L+ Y C +G S C+ +GQW G T + C+ V C P ENG T
Sbjct: 44 GSLLTYSCPQGLYPSPAS-RLCKSSGQWQTPGATRSLSKAVCKPVRCPAPVSFENGIYTP 102
Query: 799 PSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEIT--CPDPSAQIKAGS 856
+ G ++C++ + L G R C+ NG W E +C CP+P +
Sbjct: 103 RLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWDGETAVCDNGAGHCPNPGISL---- 158
Query: 857 GLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVC 902
G + G + Y+C L G R C G W+GT P+C
Sbjct: 159 GAVRTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNGVWSGTEPIC 204
Score = 74.1 bits (174), Expect = 2e-12
Identities = 61/206 (29%), Positives = 81/206 (39%), Gaps = 32/206 (15%)
Query: 646 CGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQW-------SDSS 698
C + + GT L +G GS++ YSC P R C QW S S
Sbjct: 24 CPQNVNISGGTFTLSHGWAP-GSLLTYSCPQGL-YPSPASRLCKSSGQWQTPGATRSLSK 81
Query: 699 PRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYK 758
C+ +RC P+ E I + +G+ Y +G V + CE G+
Sbjct: 82 AVCKPVRCPAPVSFENGIYTPR------------------LGS-YPVGGNVSFECEDGFI 122
Query: 759 VIGESLSTCEDNGQWSGTTPTCQ--YVDCGNPGRIENGKVTLPSNATFYGATAFYQCDEN 816
+ G + C NG W G T C C NPG I G V +G Y+C N
Sbjct: 123 LRGSPVRQCRPNGMWDGETAVCDNGAGHCPNPG-ISLGAVRTGFRFG-HGDKVRYRCSSN 180
Query: 817 WELEGVIRRMCQENGTWSLEPPICKE 842
L G R CQ NG WS PIC++
Sbjct: 181 LVLTGSSERECQGNGVWSGTEPICRQ 206
Score = 73.7 bits (173), Expect = 3e-12
Identities = 49/166 (29%), Positives = 68/166 (40%), Gaps = 11/166 (6%)
Query: 332 WNDVGCNLDYLHWICQYLPPTCGSPDKLLN---TTILGNDYDVGSRIVYKCPEGHMLLGD 388
W G +C+ P C +P N T LG+ Y VG + ++C +G +L G
Sbjct: 70 WQTPGATRSLSKAVCK--PVRCPAPVSFENGIYTPRLGS-YPVGGNVSFECEDGFILRGS 126
Query: 389 KSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDN--RTTHGARALYSCRENFTLV 446
R C+ +G W G C N G P + + R HG + Y C N L
Sbjct: 127 PVRQCRPNGMWDGETAVCD--NGAGHCPNPGISLGAVRTGFRFGHGDKVRYRCSSNLVLT 184
Query: 447 GNPERTCGDEGIWDGEAPRCLFDWCPD-PPAVSNASVTVNGHKAGS 491
G+ ER C G+W G P C + D P V+ A T H G+
Sbjct: 185 GSSERECQGNGVWSGTEPICRQPYSYDFPEDVAPALGTSFSHMLGA 230
Score = 67.7 bits (158), Expect = 2e-10
Identities = 50/181 (27%), Positives = 75/181 (41%), Gaps = 15/181 (8%)
Query: 534 IHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKW-------SYDIPSCELT 586
I G+F L +G GS+ ++C + + A L C G+W S C+
Sbjct: 30 ISGGTFTLSHGWAP-GSLLTYSCPQGLYPSPASRL-CKSSGQWQTPGATRSLSKAVCKPV 87
Query: 587 SCPEP-EVPSGGYMEAFDYY-VHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYI 644
CP P +G Y Y V ++F CE G L G P C+ +G W G++ C+
Sbjct: 88 RCPAPVSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWDGETAVCDN- 146
Query: 645 DCGKLPT--LPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCE 702
G P + G + H G ++Y C++N L G R C WS + P C
Sbjct: 147 GAGHCPNPGISLGAVRTGFRFGH-GDKVRYRCSSNLVLTGSSERECQGNGVWSGTEPICR 205
Query: 703 E 703
+
Sbjct: 206 Q 206
Score = 53.2 bits (122), Expect = 5e-06
Identities = 34/137 (24%), Positives = 53/137 (38%), Gaps = 8/137 (5%)
Query: 844 TCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNG------ 897
+ P + G ++ + G Y C +G +R C S GQW
Sbjct: 20 SAPSCPQNVNISGGTFTLSHGWAPGSLLTYSCPQGL-YPSPASRLCKSSGQWQTPGATRS 78
Query: 898 -TVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWS 956
+ VC P+ C +P + ENG GS G +V + C + G +R+C +G W
Sbjct: 79 LSKAVCKPVRCPAPVSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWD 138
Query: 957 GEEPSCELATNEAVDSG 973
GE C+ + G
Sbjct: 139 GETAVCDNGAGHCPNPG 155
>AL645922-5|CAI41722.1| 752|Homo sapiens complement component 2
protein.
Length = 752
Score = 85.0 bits (201), Expect = 1e-15
Identities = 55/173 (31%), Positives = 71/173 (41%), Gaps = 10/173 (5%)
Query: 362 TTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWS--GAPPS-----CKYVNCGGL 414
T L + + GS + Y CP+G + SR CK G W GA S CK V C
Sbjct: 34 TFTLSHGWAPGSLLTYSCPQG-LYPSPASRLCKSSGQWQTPGATRSLSKAVCKPVRCPAP 92
Query: 415 TPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL--FDWCP 472
E+G G + C + F L G+P R C G+WDGE C CP
Sbjct: 93 VSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWDGETAVCDNGAGHCP 152
Query: 473 DPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCK 525
+P A T G Y C + +L+GS+ C G WSG P C+
Sbjct: 153 NPGISLGAVRTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNGVWSGTEPICR 205
Score = 77.4 bits (182), Expect = 3e-13
Identities = 50/182 (27%), Positives = 72/182 (39%), Gaps = 12/182 (6%)
Query: 471 CPDPPAVSNASVTVN-GHKAGSLASYTCENGHILSGSTSVTCTLGGAWS--GVPPS---- 523
CP +S + T++ G GSL +Y+C G + S C G W G S
Sbjct: 24 CPQNVNISGGTFTLSHGWAPGSLLTYSCPQG-LYPSPASRLCKSSGQWQTPGATRSLSKA 82
Query: 524 -CKYVNCGTP-TIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIP 581
CK V C P + G + G+ G F CE + L G+ C +G W +
Sbjct: 83 VCKPVRCPAPVSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWDGETA 142
Query: 582 SCELTS--CPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSP 639
C+ + CP P + G F + + + C + L G CQ +G WSG P
Sbjct: 143 VCDNGAGHCPNPGISLGAVRTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNGVWSGTEP 202
Query: 640 TC 641
C
Sbjct: 203 IC 204
Score = 77.4 bits (182), Expect = 3e-13
Identities = 56/189 (29%), Positives = 78/189 (41%), Gaps = 19/189 (10%)
Query: 785 CGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTW-------SLEP 837
C I G TL S+ G+ Y C + R+C+ +G W SL
Sbjct: 24 CPQNVNISGGTFTL-SHGWAPGSLLTYSCPQGL-YPSPASRLCKSSGQWQTPGATRSLSK 81
Query: 838 PICKEITCPDPSAQIKAGSGLLVVT-STLSIGGEAHYQCERGYNLKGHQTRTCISKGQWN 896
+CK + CP P + +G+ + +GG ++CE G+ L+G R C G W+
Sbjct: 82 AVCKPVRCPAP---VSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWD 138
Query: 897 GTVPVCI--PIDCRSPGNIENGKIVISNGSTL-FGSSVEYYCLSQYQRVGPFLRKCLDDG 953
G VC C +PG I G + G G V Y C S G R+C +G
Sbjct: 139 GETAVCDNGAGHCPNPG-ISLG--AVRTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNG 195
Query: 954 RWSGEEPSC 962
WSG EP C
Sbjct: 196 VWSGTEPIC 204
Score = 76.2 bits (179), Expect = 6e-13
Identities = 48/166 (28%), Positives = 70/166 (42%), Gaps = 14/166 (8%)
Query: 746 GALVKYRCEKGYKVIGESLSTCEDNGQWS--GTTPT-----CQYVDCGNPGRIENGKVTL 798
G+L+ Y C +G S C+ +GQW G T + C+ V C P ENG T
Sbjct: 44 GSLLTYSCPQGLYPSPAS-RLCKSSGQWQTPGATRSLSKAVCKPVRCPAPVSFENGIYTP 102
Query: 799 PSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEIT--CPDPSAQIKAGS 856
+ G ++C++ + L G R C+ NG W E +C CP+P +
Sbjct: 103 RLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWDGETAVCDNGAGHCPNPGISL---- 158
Query: 857 GLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVC 902
G + G + Y+C L G R C G W+GT P+C
Sbjct: 159 GAVRTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNGVWSGTEPIC 204
Score = 74.1 bits (174), Expect = 2e-12
Identities = 61/206 (29%), Positives = 81/206 (39%), Gaps = 32/206 (15%)
Query: 646 CGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQW-------SDSS 698
C + + GT L +G GS++ YSC P R C QW S S
Sbjct: 24 CPQNVNISGGTFTLSHGWAP-GSLLTYSCPQGL-YPSPASRLCKSSGQWQTPGATRSLSK 81
Query: 699 PRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYK 758
C+ +RC P+ E I + +G+ Y +G V + CE G+
Sbjct: 82 AVCKPVRCPAPVSFENGIYTPR------------------LGS-YPVGGNVSFECEDGFI 122
Query: 759 VIGESLSTCEDNGQWSGTTPTCQ--YVDCGNPGRIENGKVTLPSNATFYGATAFYQCDEN 816
+ G + C NG W G T C C NPG I G V +G Y+C N
Sbjct: 123 LRGSPVRQCRPNGMWDGETAVCDNGAGHCPNPG-ISLGAVRTGFRFG-HGDKVRYRCSSN 180
Query: 817 WELEGVIRRMCQENGTWSLEPPICKE 842
L G R CQ NG WS PIC++
Sbjct: 181 LVLTGSSERECQGNGVWSGTEPICRQ 206
Score = 73.7 bits (173), Expect = 3e-12
Identities = 49/166 (29%), Positives = 68/166 (40%), Gaps = 11/166 (6%)
Query: 332 WNDVGCNLDYLHWICQYLPPTCGSPDKLLN---TTILGNDYDVGSRIVYKCPEGHMLLGD 388
W G +C+ P C +P N T LG+ Y VG + ++C +G +L G
Sbjct: 70 WQTPGATRSLSKAVCK--PVRCPAPVSFENGIYTPRLGS-YPVGGNVSFECEDGFILRGS 126
Query: 389 KSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDN--RTTHGARALYSCRENFTLV 446
R C+ +G W G C N G P + + R HG + Y C N L
Sbjct: 127 PVRQCRPNGMWDGETAVCD--NGAGHCPNPGISLGAVRTGFRFGHGDKVRYRCSSNLVLT 184
Query: 447 GNPERTCGDEGIWDGEAPRCLFDWCPD-PPAVSNASVTVNGHKAGS 491
G+ ER C G+W G P C + D P V+ A T H G+
Sbjct: 185 GSSERECQGNGVWSGTEPICRQPYSYDFPEDVAPALGTSFSHMLGA 230
Score = 67.7 bits (158), Expect = 2e-10
Identities = 50/181 (27%), Positives = 75/181 (41%), Gaps = 15/181 (8%)
Query: 534 IHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKW-------SYDIPSCELT 586
I G+F L +G GS+ ++C + + A L C G+W S C+
Sbjct: 30 ISGGTFTLSHGWAP-GSLLTYSCPQGLYPSPASRL-CKSSGQWQTPGATRSLSKAVCKPV 87
Query: 587 SCPEP-EVPSGGYMEAFDYY-VHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYI 644
CP P +G Y Y V ++F CE G L G P C+ +G W G++ C+
Sbjct: 88 RCPAPVSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWDGETAVCDN- 146
Query: 645 DCGKLPT--LPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCE 702
G P + G + H G ++Y C++N L G R C WS + P C
Sbjct: 147 GAGHCPNPGISLGAVRTGFRFGH-GDKVRYRCSSNLVLTGSSERECQGNGVWSGTEPICR 205
Query: 703 E 703
+
Sbjct: 206 Q 206
Score = 53.2 bits (122), Expect = 5e-06
Identities = 34/137 (24%), Positives = 53/137 (38%), Gaps = 8/137 (5%)
Query: 844 TCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNG------ 897
+ P + G ++ + G Y C +G +R C S GQW
Sbjct: 20 SAPSCPQNVNISGGTFTLSHGWAPGSLLTYSCPQGL-YPSPASRLCKSSGQWQTPGATRS 78
Query: 898 -TVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWS 956
+ VC P+ C +P + ENG GS G +V + C + G +R+C +G W
Sbjct: 79 LSKAVCKPVRCPAPVSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWD 138
Query: 957 GEEPSCELATNEAVDSG 973
GE C+ + G
Sbjct: 139 GETAVCDNGAGHCPNPG 155
>AK222783-1|BAD96503.1| 752|Homo sapiens complement component 2
precursor variant protein.
Length = 752
Score = 85.0 bits (201), Expect = 1e-15
Identities = 55/173 (31%), Positives = 71/173 (41%), Gaps = 10/173 (5%)
Query: 362 TTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWS--GAPPS-----CKYVNCGGL 414
T L + + GS + Y CP+G + SR CK G W GA S CK V C
Sbjct: 34 TFTLSHGWAPGSLLTYSCPQG-LYPSPASRLCKSSGQWQTPGATRSLSKAVCKPVRCPAP 92
Query: 415 TPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL--FDWCP 472
E+G G + C + F L G+P R C G+WDGE C CP
Sbjct: 93 VSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWDGETAVCDNGAGHCP 152
Query: 473 DPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCK 525
+P A T G Y C + +L+GS+ C G WSG P C+
Sbjct: 153 NPGISLGAVRTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNGVWSGTEPICR 205
Score = 77.4 bits (182), Expect = 3e-13
Identities = 50/182 (27%), Positives = 72/182 (39%), Gaps = 12/182 (6%)
Query: 471 CPDPPAVSNASVTVN-GHKAGSLASYTCENGHILSGSTSVTCTLGGAWS--GVPPS---- 523
CP +S + T++ G GSL +Y+C G + S C G W G S
Sbjct: 24 CPQNVNISGGTFTLSHGWAPGSLLTYSCPQG-LYPSPASRLCKSSGQWQTPGATRSLSKA 82
Query: 524 -CKYVNCGTP-TIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIP 581
CK V C P + G + G+ G F CE + L G+ C +G W +
Sbjct: 83 VCKPVRCPAPVSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWDGETA 142
Query: 582 SCELTS--CPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSP 639
C+ + CP P + G F + + + C + L G CQ +G WSG P
Sbjct: 143 VCDNGAGHCPNPGISLGAVRTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNGVWSGTEP 202
Query: 640 TC 641
C
Sbjct: 203 IC 204
Score = 77.4 bits (182), Expect = 3e-13
Identities = 56/189 (29%), Positives = 78/189 (41%), Gaps = 19/189 (10%)
Query: 785 CGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTW-------SLEP 837
C I G TL S+ G+ Y C + R+C+ +G W SL
Sbjct: 24 CPQNVNISGGTFTL-SHGWAPGSLLTYSCPQGL-YPSPASRLCKSSGQWQTPGATRSLSK 81
Query: 838 PICKEITCPDPSAQIKAGSGLLVVT-STLSIGGEAHYQCERGYNLKGHQTRTCISKGQWN 896
+CK + CP P + +G+ + +GG ++CE G+ L+G R C G W+
Sbjct: 82 AVCKPVRCPAP---VSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWD 138
Query: 897 GTVPVCI--PIDCRSPGNIENGKIVISNGSTL-FGSSVEYYCLSQYQRVGPFLRKCLDDG 953
G VC C +PG I G + G G V Y C S G R+C +G
Sbjct: 139 GETAVCDNGAGHCPNPG-ISLG--AVRTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNG 195
Query: 954 RWSGEEPSC 962
WSG EP C
Sbjct: 196 VWSGTEPIC 204
Score = 76.2 bits (179), Expect = 6e-13
Identities = 48/166 (28%), Positives = 70/166 (42%), Gaps = 14/166 (8%)
Query: 746 GALVKYRCEKGYKVIGESLSTCEDNGQWS--GTTPT-----CQYVDCGNPGRIENGKVTL 798
G+L+ Y C +G S C+ +GQW G T + C+ V C P ENG T
Sbjct: 44 GSLLTYSCPQGLYPSPAS-RLCKSSGQWQTPGATRSLSKAVCKPVRCPAPVSFENGIYTP 102
Query: 799 PSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEIT--CPDPSAQIKAGS 856
+ G ++C++ + L G R C+ NG W E +C CP+P +
Sbjct: 103 RLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWDGETAVCDNGAGHCPNPGISL---- 158
Query: 857 GLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVC 902
G + G + Y+C L G R C G W+GT P+C
Sbjct: 159 GAVRTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNGVWSGTEPIC 204
Score = 74.1 bits (174), Expect = 2e-12
Identities = 61/206 (29%), Positives = 81/206 (39%), Gaps = 32/206 (15%)
Query: 646 CGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQW-------SDSS 698
C + + GT L +G GS++ YSC P R C QW S S
Sbjct: 24 CPQNVNISGGTFTLSHGWAP-GSLLTYSCPQGL-YPSPASRLCKSSGQWQTPGATRSLSK 81
Query: 699 PRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYK 758
C+ +RC P+ E I + +G+ Y +G V + CE G+
Sbjct: 82 AVCKPVRCPAPVSFENGIYTPR------------------LGS-YPVGGNVSFECEDGFI 122
Query: 759 VIGESLSTCEDNGQWSGTTPTCQ--YVDCGNPGRIENGKVTLPSNATFYGATAFYQCDEN 816
+ G + C NG W G T C C NPG I G V +G Y+C N
Sbjct: 123 LRGSPVRQCRPNGMWDGETAVCDNGAGHCPNPG-ISLGAVRTGFRFG-HGDKVRYRCSSN 180
Query: 817 WELEGVIRRMCQENGTWSLEPPICKE 842
L G R CQ NG WS PIC++
Sbjct: 181 LVLTGSSERECQGNGVWSGTEPICRQ 206
Score = 72.1 bits (169), Expect = 1e-11
Identities = 48/166 (28%), Positives = 67/166 (40%), Gaps = 11/166 (6%)
Query: 332 WNDVGCNLDYLHWICQYLPPTCGSPDKLLN---TTILGNDYDVGSRIVYKCPEGHMLLGD 388
W G +C+ P C +P N T LG+ Y VG + ++C +G +L G
Sbjct: 70 WQTPGATRSLSKAVCK--PVRCPAPVSFENGIYTPRLGS-YPVGGNVSFECEDGFILRGS 126
Query: 389 KSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDN--RTTHGARALYSCRENFTLV 446
R C+ +G W G C N G P + + R HG + Y C N L
Sbjct: 127 PVRQCRPNGMWDGETAVCD--NGAGHCPNPGISLGAVRTGFRFGHGDKVRYRCSSNLVLT 184
Query: 447 GNPERTCGDEGIWDGEAPRCLFDWCPD-PPAVSNASVTVNGHKAGS 491
G+ ER C G+W G P C + D P + A T H G+
Sbjct: 185 GSSERECQGNGVWSGTEPICRQPYSYDFPEDAAPALGTSFSHMLGA 230
Score = 67.7 bits (158), Expect = 2e-10
Identities = 50/181 (27%), Positives = 75/181 (41%), Gaps = 15/181 (8%)
Query: 534 IHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKW-------SYDIPSCELT 586
I G+F L +G GS+ ++C + + A L C G+W S C+
Sbjct: 30 ISGGTFTLSHGWAP-GSLLTYSCPQGLYPSPASRL-CKSSGQWQTPGATRSLSKAVCKPV 87
Query: 587 SCPEP-EVPSGGYMEAFDYY-VHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYI 644
CP P +G Y Y V ++F CE G L G P C+ +G W G++ C+
Sbjct: 88 RCPAPVSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWDGETAVCDN- 146
Query: 645 DCGKLPT--LPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCE 702
G P + G + H G ++Y C++N L G R C WS + P C
Sbjct: 147 GAGHCPNPGISLGAVRTGFRFGH-GDKVRYRCSSNLVLTGSSERECQGNGVWSGTEPICR 205
Query: 703 E 703
+
Sbjct: 206 Q 206
Score = 53.2 bits (122), Expect = 5e-06
Identities = 34/137 (24%), Positives = 53/137 (38%), Gaps = 8/137 (5%)
Query: 844 TCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNG------ 897
+ P + G ++ + G Y C +G +R C S GQW
Sbjct: 20 SAPSCPQNVNISGGTFTLSHGWAPGSLLTYSCPQGL-YPSPASRLCKSSGQWQTPGATRS 78
Query: 898 -TVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWS 956
+ VC P+ C +P + ENG GS G +V + C + G +R+C +G W
Sbjct: 79 LSKAVCKPVRCPAPVSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWD 138
Query: 957 GEEPSCELATNEAVDSG 973
GE C+ + G
Sbjct: 139 GETAVCDNGAGHCPNPG 155
>AK222537-1|BAD96257.1| 752|Homo sapiens complement component 2
precursor variant protein.
Length = 752
Score = 85.0 bits (201), Expect = 1e-15
Identities = 55/173 (31%), Positives = 71/173 (41%), Gaps = 10/173 (5%)
Query: 362 TTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWS--GAPPS-----CKYVNCGGL 414
T L + + GS + Y CP+G + SR CK G W GA S CK V C
Sbjct: 34 TFTLSHGWAPGSLLTYSCPQG-LYPSPASRLCKSSGQWQTPGATRSLSKAVCKPVRCPAP 92
Query: 415 TPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL--FDWCP 472
E+G G + C + F L G+P R C G+WDGE C CP
Sbjct: 93 VSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWDGETAVCDNGAGHCP 152
Query: 473 DPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCK 525
+P A T G Y C + +L+GS+ C G WSG P C+
Sbjct: 153 NPGISLGAVRTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNGVWSGTEPICR 205
Score = 77.4 bits (182), Expect = 3e-13
Identities = 50/182 (27%), Positives = 72/182 (39%), Gaps = 12/182 (6%)
Query: 471 CPDPPAVSNASVTVN-GHKAGSLASYTCENGHILSGSTSVTCTLGGAWS--GVPPS---- 523
CP +S + T++ G GSL +Y+C G + S C G W G S
Sbjct: 24 CPQNVNISGGTFTLSHGWAPGSLLTYSCPQG-LYPSPASRLCKSSGQWQTPGATRSLSKA 82
Query: 524 -CKYVNCGTP-TIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIP 581
CK V C P + G + G+ G F CE + L G+ C +G W +
Sbjct: 83 VCKPVRCPAPVSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWDGETA 142
Query: 582 SCELTS--CPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSP 639
C+ + CP P + G F + + + C + L G CQ +G WSG P
Sbjct: 143 VCDNGAGHCPNPGISLGAVRTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNGVWSGTEP 202
Query: 640 TC 641
C
Sbjct: 203 IC 204
Score = 77.4 bits (182), Expect = 3e-13
Identities = 56/189 (29%), Positives = 78/189 (41%), Gaps = 19/189 (10%)
Query: 785 CGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTW-------SLEP 837
C I G TL S+ G+ Y C + R+C+ +G W SL
Sbjct: 24 CPQNVNISGGTFTL-SHGWAPGSLLTYSCPQGL-YPSPASRLCKSSGQWQTPGATRSLSK 81
Query: 838 PICKEITCPDPSAQIKAGSGLLVVT-STLSIGGEAHYQCERGYNLKGHQTRTCISKGQWN 896
+CK + CP P + +G+ + +GG ++CE G+ L+G R C G W+
Sbjct: 82 AVCKPVRCPAP---VSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWD 138
Query: 897 GTVPVCI--PIDCRSPGNIENGKIVISNGSTL-FGSSVEYYCLSQYQRVGPFLRKCLDDG 953
G VC C +PG I G + G G V Y C S G R+C +G
Sbjct: 139 GETAVCDNGAGHCPNPG-ISLG--AVRTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNG 195
Query: 954 RWSGEEPSC 962
WSG EP C
Sbjct: 196 VWSGTEPIC 204
Score = 76.2 bits (179), Expect = 6e-13
Identities = 48/166 (28%), Positives = 70/166 (42%), Gaps = 14/166 (8%)
Query: 746 GALVKYRCEKGYKVIGESLSTCEDNGQWS--GTTPT-----CQYVDCGNPGRIENGKVTL 798
G+L+ Y C +G S C+ +GQW G T + C+ V C P ENG T
Sbjct: 44 GSLLTYSCPQGLYPSPAS-RLCKSSGQWQTPGATRSLSKAVCKPVRCPAPVSFENGIYTP 102
Query: 799 PSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEIT--CPDPSAQIKAGS 856
+ G ++C++ + L G R C+ NG W E +C CP+P +
Sbjct: 103 RLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWDGETAVCDNGAGHCPNPGISL---- 158
Query: 857 GLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVC 902
G + G + Y+C L G R C G W+GT P+C
Sbjct: 159 GAVRTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNGVWSGTEPIC 204
Score = 74.1 bits (174), Expect = 2e-12
Identities = 61/206 (29%), Positives = 81/206 (39%), Gaps = 32/206 (15%)
Query: 646 CGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQW-------SDSS 698
C + + GT L +G GS++ YSC P R C QW S S
Sbjct: 24 CPQNVNISGGTFTLSHGWAP-GSLLTYSCPQGL-YPSPASRLCKSSGQWQTPGATRSLSK 81
Query: 699 PRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYK 758
C+ +RC P+ E I + +G+ Y +G V + CE G+
Sbjct: 82 AVCKPVRCPAPVSFENGIYTPR------------------LGS-YPVGGNVSFECEDGFI 122
Query: 759 VIGESLSTCEDNGQWSGTTPTCQ--YVDCGNPGRIENGKVTLPSNATFYGATAFYQCDEN 816
+ G + C NG W G T C C NPG I G V +G Y+C N
Sbjct: 123 LRGSPVRQCRPNGMWDGETAVCDNGAGHCPNPG-ISLGAVRTGFRFG-HGDKVRYRCSSN 180
Query: 817 WELEGVIRRMCQENGTWSLEPPICKE 842
L G R CQ NG WS PIC++
Sbjct: 181 LVLTGSSERECQGNGVWSGTEPICRQ 206
Score = 73.7 bits (173), Expect = 3e-12
Identities = 49/166 (29%), Positives = 68/166 (40%), Gaps = 11/166 (6%)
Query: 332 WNDVGCNLDYLHWICQYLPPTCGSPDKLLN---TTILGNDYDVGSRIVYKCPEGHMLLGD 388
W G +C+ P C +P N T LG+ Y VG + ++C +G +L G
Sbjct: 70 WQTPGATRSLSKAVCK--PVRCPAPVSFENGIYTPRLGS-YPVGGNVSFECEDGFILRGS 126
Query: 389 KSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDN--RTTHGARALYSCRENFTLV 446
R C+ +G W G C N G P + + R HG + Y C N L
Sbjct: 127 PVRQCRPNGMWDGETAVCD--NGAGHCPNPGISLGAVRTGFRFGHGDKVRYRCSSNLVLT 184
Query: 447 GNPERTCGDEGIWDGEAPRCLFDWCPD-PPAVSNASVTVNGHKAGS 491
G+ ER C G+W G P C + D P V+ A T H G+
Sbjct: 185 GSSERECQGNGVWSGTEPICRQPYSYDFPEDVAPALGTSFSHMLGA 230
Score = 67.7 bits (158), Expect = 2e-10
Identities = 50/181 (27%), Positives = 75/181 (41%), Gaps = 15/181 (8%)
Query: 534 IHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKW-------SYDIPSCELT 586
I G+F L +G GS+ ++C + + A L C G+W S C+
Sbjct: 30 ISGGTFTLSHGWAP-GSLLTYSCPQGLYPSPASRL-CKSSGQWQTPGATRSLSKAVCKPV 87
Query: 587 SCPEP-EVPSGGYMEAFDYY-VHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYI 644
CP P +G Y Y V ++F CE G L G P C+ +G W G++ C+
Sbjct: 88 RCPAPVSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWDGETAVCDN- 146
Query: 645 DCGKLPT--LPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCE 702
G P + G + H G ++Y C++N L G R C WS + P C
Sbjct: 147 GAGHCPNPGISLGAVRTGFRFGH-GDKVRYRCSSNLVLTGSSERECQGNGVWSGTEPICR 205
Query: 703 E 703
+
Sbjct: 206 Q 206
Score = 53.2 bits (122), Expect = 5e-06
Identities = 34/137 (24%), Positives = 53/137 (38%), Gaps = 8/137 (5%)
Query: 844 TCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNG------ 897
+ P + G ++ + G Y C +G +R C S GQW
Sbjct: 20 SAPSCPQNVNISGGTFTLSHGWAPGSLLTYSCPQGL-YPSPASRLCKSSGQWQTPGATRS 78
Query: 898 -TVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWS 956
+ VC P+ C +P + ENG GS G +V + C + G +R+C +G W
Sbjct: 79 LSKAVCKPVRCPAPVSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWD 138
Query: 957 GEEPSCELATNEAVDSG 973
GE C+ + G
Sbjct: 139 GETAVCDNGAGHCPNPG 155
>AF019413-9|AAB67975.1| 752|Homo sapiens complement component C2
protein.
Length = 752
Score = 85.0 bits (201), Expect = 1e-15
Identities = 55/173 (31%), Positives = 71/173 (41%), Gaps = 10/173 (5%)
Query: 362 TTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWS--GAPPS-----CKYVNCGGL 414
T L + + GS + Y CP+G + SR CK G W GA S CK V C
Sbjct: 34 TFTLSHGWAPGSLLTYSCPQG-LYPSPASRLCKSSGQWQTPGATRSLSKAVCKPVRCPAP 92
Query: 415 TPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL--FDWCP 472
E+G G + C + F L G+P R C G+WDGE C CP
Sbjct: 93 VSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWDGETAVCDNGAGHCP 152
Query: 473 DPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCK 525
+P A T G Y C + +L+GS+ C G WSG P C+
Sbjct: 153 NPGISLGAVRTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNGVWSGTEPICR 205
Score = 77.4 bits (182), Expect = 3e-13
Identities = 50/182 (27%), Positives = 72/182 (39%), Gaps = 12/182 (6%)
Query: 471 CPDPPAVSNASVTVN-GHKAGSLASYTCENGHILSGSTSVTCTLGGAWS--GVPPS---- 523
CP +S + T++ G GSL +Y+C G + S C G W G S
Sbjct: 24 CPQNVNISGGTFTLSHGWAPGSLLTYSCPQG-LYPSPASRLCKSSGQWQTPGATRSLSKA 82
Query: 524 -CKYVNCGTP-TIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIP 581
CK V C P + G + G+ G F CE + L G+ C +G W +
Sbjct: 83 VCKPVRCPAPVSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWDGETA 142
Query: 582 SCELTS--CPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSP 639
C+ + CP P + G F + + + C + L G CQ +G WSG P
Sbjct: 143 VCDNGAGHCPNPGISLGAVRTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNGVWSGTEP 202
Query: 640 TC 641
C
Sbjct: 203 IC 204
Score = 77.4 bits (182), Expect = 3e-13
Identities = 56/189 (29%), Positives = 78/189 (41%), Gaps = 19/189 (10%)
Query: 785 CGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTW-------SLEP 837
C I G TL S+ G+ Y C + R+C+ +G W SL
Sbjct: 24 CPQNVNISGGTFTL-SHGWAPGSLLTYSCPQGL-YPSPASRLCKSSGQWQTPGATRSLSK 81
Query: 838 PICKEITCPDPSAQIKAGSGLLVVT-STLSIGGEAHYQCERGYNLKGHQTRTCISKGQWN 896
+CK + CP P + +G+ + +GG ++CE G+ L+G R C G W+
Sbjct: 82 AVCKPVRCPAP---VSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWD 138
Query: 897 GTVPVCI--PIDCRSPGNIENGKIVISNGSTL-FGSSVEYYCLSQYQRVGPFLRKCLDDG 953
G VC C +PG I G + G G V Y C S G R+C +G
Sbjct: 139 GETAVCDNGAGHCPNPG-ISLG--AVRTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNG 195
Query: 954 RWSGEEPSC 962
WSG EP C
Sbjct: 196 VWSGTEPIC 204
Score = 76.2 bits (179), Expect = 6e-13
Identities = 48/166 (28%), Positives = 70/166 (42%), Gaps = 14/166 (8%)
Query: 746 GALVKYRCEKGYKVIGESLSTCEDNGQWS--GTTPT-----CQYVDCGNPGRIENGKVTL 798
G+L+ Y C +G S C+ +GQW G T + C+ V C P ENG T
Sbjct: 44 GSLLTYSCPQGLYPSPAS-RLCKSSGQWQTPGATRSLSKAVCKPVRCPAPVSFENGIYTP 102
Query: 799 PSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEIT--CPDPSAQIKAGS 856
+ G ++C++ + L G R C+ NG W E +C CP+P +
Sbjct: 103 RLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWDGETAVCDNGAGHCPNPGISL---- 158
Query: 857 GLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVC 902
G + G + Y+C L G R C G W+GT P+C
Sbjct: 159 GAVRTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNGVWSGTEPIC 204
Score = 74.1 bits (174), Expect = 2e-12
Identities = 61/206 (29%), Positives = 81/206 (39%), Gaps = 32/206 (15%)
Query: 646 CGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQW-------SDSS 698
C + + GT L +G GS++ YSC P R C QW S S
Sbjct: 24 CPQNVNISGGTFTLSHGWAP-GSLLTYSCPQGL-YPSPASRLCKSSGQWQTPGATRSLSK 81
Query: 699 PRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYK 758
C+ +RC P+ E I + +G+ Y +G V + CE G+
Sbjct: 82 AVCKPVRCPAPVSFENGIYTPR------------------LGS-YPVGGNVSFECEDGFI 122
Query: 759 VIGESLSTCEDNGQWSGTTPTCQ--YVDCGNPGRIENGKVTLPSNATFYGATAFYQCDEN 816
+ G + C NG W G T C C NPG I G V +G Y+C N
Sbjct: 123 LRGSPVRQCRPNGMWDGETAVCDNGAGHCPNPG-ISLGAVRTGFRFG-HGDKVRYRCSSN 180
Query: 817 WELEGVIRRMCQENGTWSLEPPICKE 842
L G R CQ NG WS PIC++
Sbjct: 181 LVLTGSSERECQGNGVWSGTEPICRQ 206
Score = 73.7 bits (173), Expect = 3e-12
Identities = 49/166 (29%), Positives = 68/166 (40%), Gaps = 11/166 (6%)
Query: 332 WNDVGCNLDYLHWICQYLPPTCGSPDKLLN---TTILGNDYDVGSRIVYKCPEGHMLLGD 388
W G +C+ P C +P N T LG+ Y VG + ++C +G +L G
Sbjct: 70 WQTPGATRSLSKAVCK--PVRCPAPVSFENGIYTPRLGS-YPVGGNVSFECEDGFILRGS 126
Query: 389 KSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDN--RTTHGARALYSCRENFTLV 446
R C+ +G W G C N G P + + R HG + Y C N L
Sbjct: 127 PVRQCRPNGMWDGETAVCD--NGAGHCPNPGISLGAVRTGFRFGHGDKVRYRCSSNLVLT 184
Query: 447 GNPERTCGDEGIWDGEAPRCLFDWCPD-PPAVSNASVTVNGHKAGS 491
G+ ER C G+W G P C + D P V+ A T H G+
Sbjct: 185 GSSERECQGNGVWSGTEPICRQPYSYDFPEDVAPALGTSFSHMLGA 230
Score = 67.7 bits (158), Expect = 2e-10
Identities = 50/181 (27%), Positives = 75/181 (41%), Gaps = 15/181 (8%)
Query: 534 IHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKW-------SYDIPSCELT 586
I G+F L +G GS+ ++C + + A L C G+W S C+
Sbjct: 30 ISGGTFTLSHGWAP-GSLLTYSCPQGLYPSPASRL-CKSSGQWQTPGATRSLSKAVCKPV 87
Query: 587 SCPEP-EVPSGGYMEAFDYY-VHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYI 644
CP P +G Y Y V ++F CE G L G P C+ +G W G++ C+
Sbjct: 88 RCPAPVSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWDGETAVCDN- 146
Query: 645 DCGKLPT--LPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCE 702
G P + G + H G ++Y C++N L G R C WS + P C
Sbjct: 147 GAGHCPNPGISLGAVRTGFRFGH-GDKVRYRCSSNLVLTGSSERECQGNGVWSGTEPICR 205
Query: 703 E 703
+
Sbjct: 206 Q 206
Score = 53.2 bits (122), Expect = 5e-06
Identities = 34/137 (24%), Positives = 53/137 (38%), Gaps = 8/137 (5%)
Query: 844 TCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNG------ 897
+ P + G ++ + G Y C +G +R C S GQW
Sbjct: 20 SAPSCPQNVNISGGTFTLSHGWAPGSLLTYSCPQGL-YPSPASRLCKSSGQWQTPGATRS 78
Query: 898 -TVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWS 956
+ VC P+ C +P + ENG GS G +V + C + G +R+C +G W
Sbjct: 79 LSKAVCKPVRCPAPVSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWD 138
Query: 957 GEEPSCELATNEAVDSG 973
GE C+ + G
Sbjct: 139 GETAVCDNGAGHCPNPG 155
>X72875-1|CAA51389.1| 764|Homo sapiens complement factor B protein.
Length = 764
Score = 83.0 bits (196), Expect = 5e-15
Identities = 64/214 (29%), Positives = 87/214 (40%), Gaps = 25/214 (11%)
Query: 534 IHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWS---------YDIPSCE 584
I GSF L+ G ++ C ++ + C G WS C
Sbjct: 44 IKGGSFRLLQE----GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECR 99
Query: 585 LTSCPEP-EVPSGGYMEAFDYY-VHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCE 642
CP P + +G Y YY V I+FHC G+ L G N CQ +G WSG + C+
Sbjct: 100 AIHCPRPHDFENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICD 159
Query: 643 YID--CGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPR 700
C P +P GT ++ L + Y C+ L G RRTC E WS + P
Sbjct: 160 NGAGYCSN-PGIPIGTRKV-GSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPS 217
Query: 701 CEEIRCSD--PIVAEKSIVSVT----GNDRSHGH 728
C++ D VAE + S+T G D GH
Sbjct: 218 CQDSFMYDTPQEVAEAFLSSLTETIEGVDAEDGH 251
Score = 80.2 bits (189), Expect = 4e-14
Identities = 54/178 (30%), Positives = 71/178 (39%), Gaps = 20/178 (11%)
Query: 740 GNTYRI---GALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPT----------CQYVDCG 786
G ++R+ G ++Y C G+ TC G WS T T C+ + C
Sbjct: 46 GGSFRLLQEGQALEYVCPSGFYPYPVQTRTCRSTGSWS-TLKTQDQKTVRKAECRAIHCP 104
Query: 787 NPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEIT-- 844
P ENG+ S + C + + L G R CQ NG WS + IC
Sbjct: 105 RPHDFENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGY 164
Query: 845 CPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVC 902
C +P I G V S + Y C RG L+G Q RTC G W+GT P C
Sbjct: 165 CSNPGIPI----GTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSC 218
Score = 72.1 bits (169), Expect = 1e-11
Identities = 41/165 (24%), Positives = 63/165 (38%), Gaps = 12/165 (7%)
Query: 490 GSLASYTCENGHILSGSTSVTCTLGGAWSGVPPS---------CKYVNCGTP-TIHKGSF 539
G Y C +G + TC G+WS + C+ ++C P G +
Sbjct: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEY 114
Query: 540 VLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTS--CPEPEVPSGG 597
+ F C Y L G+ C +G+WS C+ + C P +P G
Sbjct: 115 WPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIGT 174
Query: 598 YMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCE 642
Y + ++ +HC G L G CQ+ G WSG P+C+
Sbjct: 175 RKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQ 219
Score = 70.1 bits (164), Expect = 4e-11
Identities = 43/165 (26%), Positives = 65/165 (39%), Gaps = 11/165 (6%)
Query: 372 GSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPS---------CKYVNCGGLTPIEDGDV 422
G + Y CP G ++R C+ G WS C+ ++C E+G+
Sbjct: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEY 114
Query: 423 ALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL--FDWCPDPPAVSNA 480
+ C + +TL G+ RTC G W G+ C +C +P
Sbjct: 115 WPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIGT 174
Query: 481 SVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCK 525
+ ++ +Y C G L GS TC GG+WSG PSC+
Sbjct: 175 RKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQ 219
Score = 67.3 bits (157), Expect = 3e-10
Identities = 52/201 (25%), Positives = 77/201 (38%), Gaps = 15/201 (7%)
Query: 667 GSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSH 726
G ++Y C + + RTC WS ++ D K+ R H
Sbjct: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWST-------LKTQDQKTVRKAECRAIHCPRPH 107
Query: 727 GHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVD-- 784
+ Y + + + C GY + G + TC+ NG+WSG T C
Sbjct: 108 D---FENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGY 164
Query: 785 CGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEIT 844
C NPG I G + S + Y C L G RR CQE G+WS P C++
Sbjct: 165 CSNPG-IPIGTRKVGSQYRLEDSVT-YHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQDSF 222
Query: 845 CPDPSAQIKAGSGLLVVTSTL 865
D ++ A + L +T T+
Sbjct: 223 MYDTPQEV-AEAFLSSLTETI 242
Score = 66.5 bits (155), Expect = 5e-10
Identities = 49/169 (28%), Positives = 69/169 (40%), Gaps = 15/169 (8%)
Query: 806 GATAFYQCDENWELEGVIRRMCQENGTWS---------LEPPICKEITCPDPSAQIKAGS 856
G Y C + V R C+ G+WS + C+ I CP P + G
Sbjct: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPH-DFENGE 113
Query: 857 GLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPID--CRSPGNIE 914
+ ++ E + C GY L+G RTC G+W+G +C C +PG I
Sbjct: 114 -YWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPG-IP 171
Query: 915 NGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
G + + L SV Y+C G R C + G WSG EPSC+
Sbjct: 172 IGTRKVGSQYRL-EDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQ 219
Score = 54.4 bits (125), Expect = 2e-06
Identities = 34/111 (30%), Positives = 48/111 (43%), Gaps = 8/111 (7%)
Query: 369 YDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCK----YVNCGGLTPIEDGDVAL 424
Y+V I + C +G+ L G +R C+ +G WSG C Y + G+ PI V
Sbjct: 121 YNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGI-PIGTRKVG- 178
Query: 425 IDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPP 475
++ Y C TL G+ RTC + G W G P C + D P
Sbjct: 179 --SQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQDSFMYDTP 227
Score = 48.8 bits (111), Expect = 1e-04
Identities = 21/63 (33%), Positives = 31/63 (49%)
Query: 345 ICQYLPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPP 404
IC C +P + T +G+ Y + + Y C G L G + R C++ G WSG P
Sbjct: 157 ICDNGAGYCSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEP 216
Query: 405 SCK 407
SC+
Sbjct: 217 SCQ 219
Score = 32.7 bits (71), Expect = 7.4
Identities = 16/66 (24%), Positives = 28/66 (42%), Gaps = 3/66 (4%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTN 61
C +P +P R + ++ + Y C G L G+++R C G W+ P C +
Sbjct: 165 CSNPGIPIGTR-KVGSQYRLEDSV--TYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQDS 221
Query: 62 VAFRKP 67
+ P
Sbjct: 222 FMYDTP 227
>X00284-1|CAA25077.1| 244|Homo sapiens protein ( Human mRNA for
complement factor B Ba fragment. ).
Length = 244
Score = 83.0 bits (196), Expect = 5e-15
Identities = 64/214 (29%), Positives = 87/214 (40%), Gaps = 25/214 (11%)
Query: 534 IHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWS---------YDIPSCE 584
I GSF L+ G ++ C ++ + C G WS C
Sbjct: 29 IKGGSFRLLQE----GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECR 84
Query: 585 LTSCPEP-EVPSGGYMEAFDYY-VHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCE 642
CP P + +G Y YY V I+FHC G+ L G N CQ +G WSG + C+
Sbjct: 85 AIHCPRPHDFENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICD 144
Query: 643 YID--CGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPR 700
C P +P GT ++ L + Y C+ L G RRTC E WS + P
Sbjct: 145 NGAGYCSN-PGIPIGTRKV-GSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPS 202
Query: 701 CEEIRCSD--PIVAEKSIVSVT----GNDRSHGH 728
C++ D VAE + S+T G D GH
Sbjct: 203 CQDSFMYDTPQEVAEAFLSSLTETIEGVDAEDGH 236
Score = 80.2 bits (189), Expect = 4e-14
Identities = 54/178 (30%), Positives = 71/178 (39%), Gaps = 20/178 (11%)
Query: 740 GNTYRI---GALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPT----------CQYVDCG 786
G ++R+ G ++Y C G+ TC G WS T T C+ + C
Sbjct: 31 GGSFRLLQEGQALEYVCPSGFYPYPVQTRTCRSTGSWS-TLKTQDQKTVRKAECRAIHCP 89
Query: 787 NPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEIT-- 844
P ENG+ S + C + + L G R CQ NG WS + IC
Sbjct: 90 RPHDFENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGY 149
Query: 845 CPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVC 902
C +P I G V S + Y C RG L+G Q RTC G W+GT P C
Sbjct: 150 CSNPGIPI----GTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSC 203
Score = 72.1 bits (169), Expect = 1e-11
Identities = 41/165 (24%), Positives = 63/165 (38%), Gaps = 12/165 (7%)
Query: 490 GSLASYTCENGHILSGSTSVTCTLGGAWSGVPPS---------CKYVNCGTP-TIHKGSF 539
G Y C +G + TC G+WS + C+ ++C P G +
Sbjct: 40 GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEY 99
Query: 540 VLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTS--CPEPEVPSGG 597
+ F C Y L G+ C +G+WS C+ + C P +P G
Sbjct: 100 WPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIGT 159
Query: 598 YMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCE 642
Y + ++ +HC G L G CQ+ G WSG P+C+
Sbjct: 160 RKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQ 204
Score = 70.1 bits (164), Expect = 4e-11
Identities = 43/165 (26%), Positives = 65/165 (39%), Gaps = 11/165 (6%)
Query: 372 GSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPS---------CKYVNCGGLTPIEDGDV 422
G + Y CP G ++R C+ G WS C+ ++C E+G+
Sbjct: 40 GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEY 99
Query: 423 ALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL--FDWCPDPPAVSNA 480
+ C + +TL G+ RTC G W G+ C +C +P
Sbjct: 100 WPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIGT 159
Query: 481 SVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCK 525
+ ++ +Y C G L GS TC GG+WSG PSC+
Sbjct: 160 RKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQ 204
Score = 67.3 bits (157), Expect = 3e-10
Identities = 52/201 (25%), Positives = 77/201 (38%), Gaps = 15/201 (7%)
Query: 667 GSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSH 726
G ++Y C + + RTC WS ++ D K+ R H
Sbjct: 40 GQALEYVCPSGFYPYPVQTRTCRSTGSWST-------LKTQDQKTVRKAECRAIHCPRPH 92
Query: 727 GHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVD-- 784
+ Y + + + C GY + G + TC+ NG+WSG T C
Sbjct: 93 D---FENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGY 149
Query: 785 CGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEIT 844
C NPG I G + S + Y C L G RR CQE G+WS P C++
Sbjct: 150 CSNPG-IPIGTRKVGSQYRLEDSVT-YHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQDSF 207
Query: 845 CPDPSAQIKAGSGLLVVTSTL 865
D ++ A + L +T T+
Sbjct: 208 MYDTPQEV-AEAFLSSLTETI 227
Score = 66.5 bits (155), Expect = 5e-10
Identities = 49/169 (28%), Positives = 69/169 (40%), Gaps = 15/169 (8%)
Query: 806 GATAFYQCDENWELEGVIRRMCQENGTWS---------LEPPICKEITCPDPSAQIKAGS 856
G Y C + V R C+ G+WS + C+ I CP P + G
Sbjct: 40 GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPH-DFENGE 98
Query: 857 GLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPID--CRSPGNIE 914
+ ++ E + C GY L+G RTC G+W+G +C C +PG I
Sbjct: 99 -YWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPG-IP 156
Query: 915 NGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
G + + L SV Y+C G R C + G WSG EPSC+
Sbjct: 157 IGTRKVGSQYRL-EDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQ 204
Score = 54.4 bits (125), Expect = 2e-06
Identities = 34/111 (30%), Positives = 48/111 (43%), Gaps = 8/111 (7%)
Query: 369 YDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCK----YVNCGGLTPIEDGDVAL 424
Y+V I + C +G+ L G +R C+ +G WSG C Y + G+ PI V
Sbjct: 106 YNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGI-PIGTRKVG- 163
Query: 425 IDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPP 475
++ Y C TL G+ RTC + G W G P C + D P
Sbjct: 164 --SQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQDSFMYDTP 212
Score = 48.8 bits (111), Expect = 1e-04
Identities = 21/63 (33%), Positives = 31/63 (49%)
Query: 345 ICQYLPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPP 404
IC C +P + T +G+ Y + + Y C G L G + R C++ G WSG P
Sbjct: 142 ICDNGAGYCSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEP 201
Query: 405 SCK 407
SC+
Sbjct: 202 SCQ 204
Score = 32.7 bits (71), Expect = 7.4
Identities = 16/66 (24%), Positives = 28/66 (42%), Gaps = 3/66 (4%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTN 61
C +P +P R + ++ + Y C G L G+++R C G W+ P C +
Sbjct: 150 CSNPGIPIGTR-KVGSQYRLEDSV--TYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQDS 206
Query: 62 VAFRKP 67
+ P
Sbjct: 207 FMYDTP 212
>S67310-1|AAD13989.1| 764|Homo sapiens complement factor B protein.
Length = 764
Score = 83.0 bits (196), Expect = 5e-15
Identities = 64/214 (29%), Positives = 87/214 (40%), Gaps = 25/214 (11%)
Query: 534 IHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWS---------YDIPSCE 584
I GSF L+ G ++ C ++ + C G WS C
Sbjct: 44 IKGGSFRLLQE----GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECR 99
Query: 585 LTSCPEP-EVPSGGYMEAFDYY-VHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCE 642
CP P + +G Y YY V I+FHC G+ L G N CQ +G WSG + C+
Sbjct: 100 AIHCPRPHDFENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICD 159
Query: 643 YID--CGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPR 700
C P +P GT ++ L + Y C+ L G RRTC E WS + P
Sbjct: 160 NGAGYCSN-PGIPIGTRKV-GSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPS 217
Query: 701 CEEIRCSD--PIVAEKSIVSVT----GNDRSHGH 728
C++ D VAE + S+T G D GH
Sbjct: 218 CQDSFMYDTPQEVAEAFLSSLTETIEGVDAEDGH 251
Score = 80.2 bits (189), Expect = 4e-14
Identities = 54/178 (30%), Positives = 71/178 (39%), Gaps = 20/178 (11%)
Query: 740 GNTYRI---GALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPT----------CQYVDCG 786
G ++R+ G ++Y C G+ TC G WS T T C+ + C
Sbjct: 46 GGSFRLLQEGQALEYVCPSGFYPYPVQTRTCRSTGSWS-TLKTQDQKTVRKAECRAIHCP 104
Query: 787 NPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEIT-- 844
P ENG+ S + C + + L G R CQ NG WS + IC
Sbjct: 105 RPHDFENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGY 164
Query: 845 CPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVC 902
C +P I G V S + Y C RG L+G Q RTC G W+GT P C
Sbjct: 165 CSNPGIPI----GTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSC 218
Score = 72.1 bits (169), Expect = 1e-11
Identities = 41/165 (24%), Positives = 63/165 (38%), Gaps = 12/165 (7%)
Query: 490 GSLASYTCENGHILSGSTSVTCTLGGAWSGVPPS---------CKYVNCGTP-TIHKGSF 539
G Y C +G + TC G+WS + C+ ++C P G +
Sbjct: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEY 114
Query: 540 VLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTS--CPEPEVPSGG 597
+ F C Y L G+ C +G+WS C+ + C P +P G
Sbjct: 115 WPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIGT 174
Query: 598 YMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCE 642
Y + ++ +HC G L G CQ+ G WSG P+C+
Sbjct: 175 RKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQ 219
Score = 70.1 bits (164), Expect = 4e-11
Identities = 43/165 (26%), Positives = 65/165 (39%), Gaps = 11/165 (6%)
Query: 372 GSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPS---------CKYVNCGGLTPIEDGDV 422
G + Y CP G ++R C+ G WS C+ ++C E+G+
Sbjct: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEY 114
Query: 423 ALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL--FDWCPDPPAVSNA 480
+ C + +TL G+ RTC G W G+ C +C +P
Sbjct: 115 WPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIGT 174
Query: 481 SVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCK 525
+ ++ +Y C G L GS TC GG+WSG PSC+
Sbjct: 175 RKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQ 219
Score = 67.3 bits (157), Expect = 3e-10
Identities = 52/201 (25%), Positives = 77/201 (38%), Gaps = 15/201 (7%)
Query: 667 GSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSH 726
G ++Y C + + RTC WS ++ D K+ R H
Sbjct: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWST-------LKTQDQKTVRKAECRAIHCPRPH 107
Query: 727 GHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVD-- 784
+ Y + + + C GY + G + TC+ NG+WSG T C
Sbjct: 108 D---FENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGY 164
Query: 785 CGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEIT 844
C NPG I G + S + Y C L G RR CQE G+WS P C++
Sbjct: 165 CSNPG-IPIGTRKVGSQYRLEDSVT-YHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQDSF 222
Query: 845 CPDPSAQIKAGSGLLVVTSTL 865
D ++ A + L +T T+
Sbjct: 223 MYDTPQEV-AEAFLSSLTETI 242
Score = 66.5 bits (155), Expect = 5e-10
Identities = 49/169 (28%), Positives = 69/169 (40%), Gaps = 15/169 (8%)
Query: 806 GATAFYQCDENWELEGVIRRMCQENGTWS---------LEPPICKEITCPDPSAQIKAGS 856
G Y C + V R C+ G+WS + C+ I CP P + G
Sbjct: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPH-DFENGE 113
Query: 857 GLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPID--CRSPGNIE 914
+ ++ E + C GY L+G RTC G+W+G +C C +PG I
Sbjct: 114 -YWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPG-IP 171
Query: 915 NGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
G + + L SV Y+C G R C + G WSG EPSC+
Sbjct: 172 IGTRKVGSQYRL-EDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQ 219
Score = 54.4 bits (125), Expect = 2e-06
Identities = 34/111 (30%), Positives = 48/111 (43%), Gaps = 8/111 (7%)
Query: 369 YDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCK----YVNCGGLTPIEDGDVAL 424
Y+V I + C +G+ L G +R C+ +G WSG C Y + G+ PI V
Sbjct: 121 YNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGI-PIGTRKVG- 178
Query: 425 IDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPP 475
++ Y C TL G+ RTC + G W G P C + D P
Sbjct: 179 --SQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQDSFMYDTP 227
Score = 48.8 bits (111), Expect = 1e-04
Identities = 21/63 (33%), Positives = 31/63 (49%)
Query: 345 ICQYLPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPP 404
IC C +P + T +G+ Y + + Y C G L G + R C++ G WSG P
Sbjct: 157 ICDNGAGYCSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEP 216
Query: 405 SCK 407
SC+
Sbjct: 217 SCQ 219
Score = 32.7 bits (71), Expect = 7.4
Identities = 16/66 (24%), Positives = 28/66 (42%), Gaps = 3/66 (4%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTN 61
C +P +P R + ++ + Y C G L G+++R C G W+ P C +
Sbjct: 165 CSNPGIPIGTR-KVGSQYRLEDSV--TYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQDS 221
Query: 62 VAFRKP 67
+ P
Sbjct: 222 FMYDTP 227
>L15702-1|AAA16820.1| 764|Homo sapiens complement factor B protein.
Length = 764
Score = 83.0 bits (196), Expect = 5e-15
Identities = 64/214 (29%), Positives = 87/214 (40%), Gaps = 25/214 (11%)
Query: 534 IHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWS---------YDIPSCE 584
I GSF L+ G ++ C ++ + C G WS C
Sbjct: 44 IKGGSFRLLQE----GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECR 99
Query: 585 LTSCPEP-EVPSGGYMEAFDYY-VHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCE 642
CP P + +G Y YY V I+FHC G+ L G N CQ +G WSG + C+
Sbjct: 100 AIHCPRPHDFENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICD 159
Query: 643 YID--CGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPR 700
C P +P GT ++ L + Y C+ L G RRTC E WS + P
Sbjct: 160 NGAGYCSN-PGIPIGTRKV-GSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPS 217
Query: 701 CEEIRCSD--PIVAEKSIVSVT----GNDRSHGH 728
C++ D VAE + S+T G D GH
Sbjct: 218 CQDSFMYDTPQEVAEAFLSSLTETIEGVDAEDGH 251
Score = 80.2 bits (189), Expect = 4e-14
Identities = 54/178 (30%), Positives = 71/178 (39%), Gaps = 20/178 (11%)
Query: 740 GNTYRI---GALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPT----------CQYVDCG 786
G ++R+ G ++Y C G+ TC G WS T T C+ + C
Sbjct: 46 GGSFRLLQEGQALEYVCPSGFYPYPVQTRTCRSTGSWS-TLKTQDQKTVRKAECRAIHCP 104
Query: 787 NPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEIT-- 844
P ENG+ S + C + + L G R CQ NG WS + IC
Sbjct: 105 RPHDFENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGY 164
Query: 845 CPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVC 902
C +P I G V S + Y C RG L+G Q RTC G W+GT P C
Sbjct: 165 CSNPGIPI----GTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSC 218
Score = 72.1 bits (169), Expect = 1e-11
Identities = 41/165 (24%), Positives = 63/165 (38%), Gaps = 12/165 (7%)
Query: 490 GSLASYTCENGHILSGSTSVTCTLGGAWSGVPPS---------CKYVNCGTP-TIHKGSF 539
G Y C +G + TC G+WS + C+ ++C P G +
Sbjct: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEY 114
Query: 540 VLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTS--CPEPEVPSGG 597
+ F C Y L G+ C +G+WS C+ + C P +P G
Sbjct: 115 WPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIGT 174
Query: 598 YMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCE 642
Y + ++ +HC G L G CQ+ G WSG P+C+
Sbjct: 175 RKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQ 219
Score = 70.1 bits (164), Expect = 4e-11
Identities = 43/165 (26%), Positives = 65/165 (39%), Gaps = 11/165 (6%)
Query: 372 GSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPS---------CKYVNCGGLTPIEDGDV 422
G + Y CP G ++R C+ G WS C+ ++C E+G+
Sbjct: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEY 114
Query: 423 ALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL--FDWCPDPPAVSNA 480
+ C + +TL G+ RTC G W G+ C +C +P
Sbjct: 115 WPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIGT 174
Query: 481 SVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCK 525
+ ++ +Y C G L GS TC GG+WSG PSC+
Sbjct: 175 RKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQ 219
Score = 67.3 bits (157), Expect = 3e-10
Identities = 52/201 (25%), Positives = 77/201 (38%), Gaps = 15/201 (7%)
Query: 667 GSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSH 726
G ++Y C + + RTC WS ++ D K+ R H
Sbjct: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWST-------LKTQDQKTVRKAECRAIHCPRPH 107
Query: 727 GHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVD-- 784
+ Y + + + C GY + G + TC+ NG+WSG T C
Sbjct: 108 D---FENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGY 164
Query: 785 CGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEIT 844
C NPG I G + S + Y C L G RR CQE G+WS P C++
Sbjct: 165 CSNPG-IPIGTRKVGSQYRLEDSVT-YHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQDSF 222
Query: 845 CPDPSAQIKAGSGLLVVTSTL 865
D ++ A + L +T T+
Sbjct: 223 MYDTPQEV-AEAFLSSLTETI 242
Score = 66.5 bits (155), Expect = 5e-10
Identities = 49/169 (28%), Positives = 69/169 (40%), Gaps = 15/169 (8%)
Query: 806 GATAFYQCDENWELEGVIRRMCQENGTWS---------LEPPICKEITCPDPSAQIKAGS 856
G Y C + V R C+ G+WS + C+ I CP P + G
Sbjct: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPH-DFENGE 113
Query: 857 GLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPID--CRSPGNIE 914
+ ++ E + C GY L+G RTC G+W+G +C C +PG I
Sbjct: 114 -YWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPG-IP 171
Query: 915 NGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
G + + L SV Y+C G R C + G WSG EPSC+
Sbjct: 172 IGTRKVGSQYRL-EDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQ 219
Score = 54.4 bits (125), Expect = 2e-06
Identities = 34/111 (30%), Positives = 48/111 (43%), Gaps = 8/111 (7%)
Query: 369 YDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCK----YVNCGGLTPIEDGDVAL 424
Y+V I + C +G+ L G +R C+ +G WSG C Y + G+ PI V
Sbjct: 121 YNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGI-PIGTRKVG- 178
Query: 425 IDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPP 475
++ Y C TL G+ RTC + G W G P C + D P
Sbjct: 179 --SQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQDSFMYDTP 227
Score = 48.8 bits (111), Expect = 1e-04
Identities = 21/63 (33%), Positives = 31/63 (49%)
Query: 345 ICQYLPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPP 404
IC C +P + T +G+ Y + + Y C G L G + R C++ G WSG P
Sbjct: 157 ICDNGAGYCSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEP 216
Query: 405 SCK 407
SC+
Sbjct: 217 SCQ 219
Score = 32.7 bits (71), Expect = 7.4
Identities = 16/66 (24%), Positives = 28/66 (42%), Gaps = 3/66 (4%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTN 61
C +P +P R + ++ + Y C G L G+++R C G W+ P C +
Sbjct: 165 CSNPGIPIGTR-KVGSQYRLEDSV--TYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQDS 221
Query: 62 VAFRKP 67
+ P
Sbjct: 222 FMYDTP 227
>BX005143-8|CAM25864.1| 764|Homo sapiens complement factor B
protein.
Length = 764
Score = 83.0 bits (196), Expect = 5e-15
Identities = 64/214 (29%), Positives = 87/214 (40%), Gaps = 25/214 (11%)
Query: 534 IHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWS---------YDIPSCE 584
I GSF L+ G ++ C ++ + C G WS C
Sbjct: 44 IKGGSFRLLQE----GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECR 99
Query: 585 LTSCPEP-EVPSGGYMEAFDYY-VHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCE 642
CP P + +G Y YY V I+FHC G+ L G N CQ +G WSG + C+
Sbjct: 100 AIHCPRPHDFENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICD 159
Query: 643 YID--CGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPR 700
C P +P GT ++ L + Y C+ L G RRTC E WS + P
Sbjct: 160 NGAGYCSN-PGIPIGTRKV-GSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPS 217
Query: 701 CEEIRCSD--PIVAEKSIVSVT----GNDRSHGH 728
C++ D VAE + S+T G D GH
Sbjct: 218 CQDSFMYDTPQEVAEAFLSSLTETIEGVDAEDGH 251
Score = 80.2 bits (189), Expect = 4e-14
Identities = 54/178 (30%), Positives = 71/178 (39%), Gaps = 20/178 (11%)
Query: 740 GNTYRI---GALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPT----------CQYVDCG 786
G ++R+ G ++Y C G+ TC G WS T T C+ + C
Sbjct: 46 GGSFRLLQEGQALEYVCPSGFYPYPVQTRTCRSTGSWS-TLKTQDQKTVRKAECRAIHCP 104
Query: 787 NPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEIT-- 844
P ENG+ S + C + + L G R CQ NG WS + IC
Sbjct: 105 RPHDFENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGY 164
Query: 845 CPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVC 902
C +P I G V S + Y C RG L+G Q RTC G W+GT P C
Sbjct: 165 CSNPGIPI----GTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSC 218
Score = 72.1 bits (169), Expect = 1e-11
Identities = 41/165 (24%), Positives = 63/165 (38%), Gaps = 12/165 (7%)
Query: 490 GSLASYTCENGHILSGSTSVTCTLGGAWSGVPPS---------CKYVNCGTP-TIHKGSF 539
G Y C +G + TC G+WS + C+ ++C P G +
Sbjct: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEY 114
Query: 540 VLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTS--CPEPEVPSGG 597
+ F C Y L G+ C +G+WS C+ + C P +P G
Sbjct: 115 WPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIGT 174
Query: 598 YMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCE 642
Y + ++ +HC G L G CQ+ G WSG P+C+
Sbjct: 175 RKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQ 219
Score = 70.1 bits (164), Expect = 4e-11
Identities = 43/165 (26%), Positives = 65/165 (39%), Gaps = 11/165 (6%)
Query: 372 GSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPS---------CKYVNCGGLTPIEDGDV 422
G + Y CP G ++R C+ G WS C+ ++C E+G+
Sbjct: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEY 114
Query: 423 ALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL--FDWCPDPPAVSNA 480
+ C + +TL G+ RTC G W G+ C +C +P
Sbjct: 115 WPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIGT 174
Query: 481 SVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCK 525
+ ++ +Y C G L GS TC GG+WSG PSC+
Sbjct: 175 RKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQ 219
Score = 67.3 bits (157), Expect = 3e-10
Identities = 52/201 (25%), Positives = 77/201 (38%), Gaps = 15/201 (7%)
Query: 667 GSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSH 726
G ++Y C + + RTC WS ++ D K+ R H
Sbjct: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWST-------LKTQDQKTVRKAECRAIHCPRPH 107
Query: 727 GHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVD-- 784
+ Y + + + C GY + G + TC+ NG+WSG T C
Sbjct: 108 D---FENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGY 164
Query: 785 CGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEIT 844
C NPG I G + S + Y C L G RR CQE G+WS P C++
Sbjct: 165 CSNPG-IPIGTRKVGSQYRLEDSVT-YHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQDSF 222
Query: 845 CPDPSAQIKAGSGLLVVTSTL 865
D ++ A + L +T T+
Sbjct: 223 MYDTPQEV-AEAFLSSLTETI 242
Score = 66.5 bits (155), Expect = 5e-10
Identities = 49/169 (28%), Positives = 69/169 (40%), Gaps = 15/169 (8%)
Query: 806 GATAFYQCDENWELEGVIRRMCQENGTWS---------LEPPICKEITCPDPSAQIKAGS 856
G Y C + V R C+ G+WS + C+ I CP P + G
Sbjct: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPH-DFENGE 113
Query: 857 GLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPID--CRSPGNIE 914
+ ++ E + C GY L+G RTC G+W+G +C C +PG I
Sbjct: 114 -YWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPG-IP 171
Query: 915 NGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
G + + L SV Y+C G R C + G WSG EPSC+
Sbjct: 172 IGTRKVGSQYRL-EDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQ 219
Score = 54.4 bits (125), Expect = 2e-06
Identities = 34/111 (30%), Positives = 48/111 (43%), Gaps = 8/111 (7%)
Query: 369 YDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCK----YVNCGGLTPIEDGDVAL 424
Y+V I + C +G+ L G +R C+ +G WSG C Y + G+ PI V
Sbjct: 121 YNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGI-PIGTRKVG- 178
Query: 425 IDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPP 475
++ Y C TL G+ RTC + G W G P C + D P
Sbjct: 179 --SQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQDSFMYDTP 227
Score = 48.8 bits (111), Expect = 1e-04
Identities = 21/63 (33%), Positives = 31/63 (49%)
Query: 345 ICQYLPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPP 404
IC C +P + T +G+ Y + + Y C G L G + R C++ G WSG P
Sbjct: 157 ICDNGAGYCSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEP 216
Query: 405 SCK 407
SC+
Sbjct: 217 SCQ 219
Score = 32.7 bits (71), Expect = 7.4
Identities = 16/66 (24%), Positives = 28/66 (42%), Gaps = 3/66 (4%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTN 61
C +P +P R + ++ + Y C G L G+++R C G W+ P C +
Sbjct: 165 CSNPGIPIGTR-KVGSQYRLEDSV--TYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQDS 221
Query: 62 VAFRKP 67
+ P
Sbjct: 222 FMYDTP 227
>BC007990-1|AAH07990.1| 764|Homo sapiens complement factor B
protein.
Length = 764
Score = 83.0 bits (196), Expect = 5e-15
Identities = 64/214 (29%), Positives = 87/214 (40%), Gaps = 25/214 (11%)
Query: 534 IHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWS---------YDIPSCE 584
I GSF L+ G ++ C ++ + C G WS C
Sbjct: 44 IKGGSFRLLQE----GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECR 99
Query: 585 LTSCPEP-EVPSGGYMEAFDYY-VHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCE 642
CP P + +G Y YY V I+FHC G+ L G N CQ +G WSG + C+
Sbjct: 100 AIHCPRPHDFENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICD 159
Query: 643 YID--CGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPR 700
C P +P GT ++ L + Y C+ L G RRTC E WS + P
Sbjct: 160 NGAGYCSN-PGIPIGTRKV-GSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPS 217
Query: 701 CEEIRCSD--PIVAEKSIVSVT----GNDRSHGH 728
C++ D VAE + S+T G D GH
Sbjct: 218 CQDSFMYDTPQEVAEAFLSSLTETIEGVDAEDGH 251
Score = 80.2 bits (189), Expect = 4e-14
Identities = 54/178 (30%), Positives = 71/178 (39%), Gaps = 20/178 (11%)
Query: 740 GNTYRI---GALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPT----------CQYVDCG 786
G ++R+ G ++Y C G+ TC G WS T T C+ + C
Sbjct: 46 GGSFRLLQEGQALEYVCPSGFYPYPVQTRTCRSTGSWS-TLKTQDQKTVRKAECRAIHCP 104
Query: 787 NPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEIT-- 844
P ENG+ S + C + + L G R CQ NG WS + IC
Sbjct: 105 RPHDFENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGY 164
Query: 845 CPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVC 902
C +P I G V S + Y C RG L+G Q RTC G W+GT P C
Sbjct: 165 CSNPGIPI----GTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSC 218
Score = 72.1 bits (169), Expect = 1e-11
Identities = 41/165 (24%), Positives = 63/165 (38%), Gaps = 12/165 (7%)
Query: 490 GSLASYTCENGHILSGSTSVTCTLGGAWSGVPPS---------CKYVNCGTP-TIHKGSF 539
G Y C +G + TC G+WS + C+ ++C P G +
Sbjct: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEY 114
Query: 540 VLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTS--CPEPEVPSGG 597
+ F C Y L G+ C +G+WS C+ + C P +P G
Sbjct: 115 WPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIGT 174
Query: 598 YMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCE 642
Y + ++ +HC G L G CQ+ G WSG P+C+
Sbjct: 175 RKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQ 219
Score = 70.1 bits (164), Expect = 4e-11
Identities = 43/165 (26%), Positives = 65/165 (39%), Gaps = 11/165 (6%)
Query: 372 GSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPS---------CKYVNCGGLTPIEDGDV 422
G + Y CP G ++R C+ G WS C+ ++C E+G+
Sbjct: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEY 114
Query: 423 ALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL--FDWCPDPPAVSNA 480
+ C + +TL G+ RTC G W G+ C +C +P
Sbjct: 115 WPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIGT 174
Query: 481 SVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCK 525
+ ++ +Y C G L GS TC GG+WSG PSC+
Sbjct: 175 RKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQ 219
Score = 67.3 bits (157), Expect = 3e-10
Identities = 52/201 (25%), Positives = 77/201 (38%), Gaps = 15/201 (7%)
Query: 667 GSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSH 726
G ++Y C + + RTC WS ++ D K+ R H
Sbjct: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWST-------LKTQDQKTVRKAECRAIHCPRPH 107
Query: 727 GHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVD-- 784
+ Y + + + C GY + G + TC+ NG+WSG T C
Sbjct: 108 D---FENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGY 164
Query: 785 CGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEIT 844
C NPG I G + S + Y C L G RR CQE G+WS P C++
Sbjct: 165 CSNPG-IPIGTRKVGSQYRLEDSVT-YHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQDSF 222
Query: 845 CPDPSAQIKAGSGLLVVTSTL 865
D ++ A + L +T T+
Sbjct: 223 MYDTPQEV-AEAFLSSLTETI 242
Score = 66.5 bits (155), Expect = 5e-10
Identities = 49/169 (28%), Positives = 69/169 (40%), Gaps = 15/169 (8%)
Query: 806 GATAFYQCDENWELEGVIRRMCQENGTWS---------LEPPICKEITCPDPSAQIKAGS 856
G Y C + V R C+ G+WS + C+ I CP P + G
Sbjct: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPH-DFENGE 113
Query: 857 GLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPID--CRSPGNIE 914
+ ++ E + C GY L+G RTC G+W+G +C C +PG I
Sbjct: 114 -YWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPG-IP 171
Query: 915 NGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
G + + L SV Y+C G R C + G WSG EPSC+
Sbjct: 172 IGTRKVGSQYRL-EDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQ 219
Score = 54.4 bits (125), Expect = 2e-06
Identities = 34/111 (30%), Positives = 48/111 (43%), Gaps = 8/111 (7%)
Query: 369 YDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCK----YVNCGGLTPIEDGDVAL 424
Y+V I + C +G+ L G +R C+ +G WSG C Y + G+ PI V
Sbjct: 121 YNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGI-PIGTRKVG- 178
Query: 425 IDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPP 475
++ Y C TL G+ RTC + G W G P C + D P
Sbjct: 179 --SQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQDSFMYDTP 227
Score = 48.8 bits (111), Expect = 1e-04
Identities = 21/63 (33%), Positives = 31/63 (49%)
Query: 345 ICQYLPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPP 404
IC C +P + T +G+ Y + + Y C G L G + R C++ G WSG P
Sbjct: 157 ICDNGAGYCSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEP 216
Query: 405 SCK 407
SC+
Sbjct: 217 SCQ 219
Score = 32.7 bits (71), Expect = 7.4
Identities = 16/66 (24%), Positives = 28/66 (42%), Gaps = 3/66 (4%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTN 61
C +P +P R + ++ + Y C G L G+++R C G W+ P C +
Sbjct: 165 CSNPGIPIGTR-KVGSQYRLEDSV--TYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQDS 221
Query: 62 VAFRKP 67
+ P
Sbjct: 222 FMYDTP 227
>BC004143-1|AAH04143.1| 764|Homo sapiens complement factor B
protein.
Length = 764
Score = 83.0 bits (196), Expect = 5e-15
Identities = 64/214 (29%), Positives = 87/214 (40%), Gaps = 25/214 (11%)
Query: 534 IHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWS---------YDIPSCE 584
I GSF L+ G ++ C ++ + C G WS C
Sbjct: 44 IKGGSFRLLQE----GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECR 99
Query: 585 LTSCPEP-EVPSGGYMEAFDYY-VHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCE 642
CP P + +G Y YY V I+FHC G+ L G N CQ +G WSG + C+
Sbjct: 100 AIHCPRPHDFENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICD 159
Query: 643 YID--CGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPR 700
C P +P GT ++ L + Y C+ L G RRTC E WS + P
Sbjct: 160 NGAGYCSN-PGIPIGTRKV-GSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPS 217
Query: 701 CEEIRCSD--PIVAEKSIVSVT----GNDRSHGH 728
C++ D VAE + S+T G D GH
Sbjct: 218 CQDSFMYDTPQEVAEAFLSSLTETIEGVDAEDGH 251
Score = 80.2 bits (189), Expect = 4e-14
Identities = 54/178 (30%), Positives = 71/178 (39%), Gaps = 20/178 (11%)
Query: 740 GNTYRI---GALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPT----------CQYVDCG 786
G ++R+ G ++Y C G+ TC G WS T T C+ + C
Sbjct: 46 GGSFRLLQEGQALEYVCPSGFYPYPVQTRTCRSTGSWS-TLKTQDQKTVRKAECRAIHCP 104
Query: 787 NPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEIT-- 844
P ENG+ S + C + + L G R CQ NG WS + IC
Sbjct: 105 RPHDFENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGY 164
Query: 845 CPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVC 902
C +P I G V S + Y C RG L+G Q RTC G W+GT P C
Sbjct: 165 CSNPGIPI----GTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSC 218
Score = 72.1 bits (169), Expect = 1e-11
Identities = 41/165 (24%), Positives = 63/165 (38%), Gaps = 12/165 (7%)
Query: 490 GSLASYTCENGHILSGSTSVTCTLGGAWSGVPPS---------CKYVNCGTP-TIHKGSF 539
G Y C +G + TC G+WS + C+ ++C P G +
Sbjct: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEY 114
Query: 540 VLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTS--CPEPEVPSGG 597
+ F C Y L G+ C +G+WS C+ + C P +P G
Sbjct: 115 WPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIGT 174
Query: 598 YMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCE 642
Y + ++ +HC G L G CQ+ G WSG P+C+
Sbjct: 175 RKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQ 219
Score = 70.1 bits (164), Expect = 4e-11
Identities = 43/165 (26%), Positives = 65/165 (39%), Gaps = 11/165 (6%)
Query: 372 GSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPS---------CKYVNCGGLTPIEDGDV 422
G + Y CP G ++R C+ G WS C+ ++C E+G+
Sbjct: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEY 114
Query: 423 ALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL--FDWCPDPPAVSNA 480
+ C + +TL G+ RTC G W G+ C +C +P
Sbjct: 115 WPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIGT 174
Query: 481 SVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCK 525
+ ++ +Y C G L GS TC GG+WSG PSC+
Sbjct: 175 RKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQ 219
Score = 67.3 bits (157), Expect = 3e-10
Identities = 52/201 (25%), Positives = 77/201 (38%), Gaps = 15/201 (7%)
Query: 667 GSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSH 726
G ++Y C + + RTC WS ++ D K+ R H
Sbjct: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWST-------LKTQDQKTVRKAECRAIHCPRPH 107
Query: 727 GHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVD-- 784
+ Y + + + C GY + G + TC+ NG+WSG T C
Sbjct: 108 D---FENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGY 164
Query: 785 CGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEIT 844
C NPG I G + S + Y C L G RR CQE G+WS P C++
Sbjct: 165 CSNPG-IPIGTRKVGSQYRLEDSVT-YHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQDSF 222
Query: 845 CPDPSAQIKAGSGLLVVTSTL 865
D ++ A + L +T T+
Sbjct: 223 MYDTPQEV-AEAFLSSLTETI 242
Score = 66.5 bits (155), Expect = 5e-10
Identities = 49/169 (28%), Positives = 69/169 (40%), Gaps = 15/169 (8%)
Query: 806 GATAFYQCDENWELEGVIRRMCQENGTWS---------LEPPICKEITCPDPSAQIKAGS 856
G Y C + V R C+ G+WS + C+ I CP P + G
Sbjct: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPH-DFENGE 113
Query: 857 GLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPID--CRSPGNIE 914
+ ++ E + C GY L+G RTC G+W+G +C C +PG I
Sbjct: 114 -YWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPG-IP 171
Query: 915 NGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
G + + L SV Y+C G R C + G WSG EPSC+
Sbjct: 172 IGTRKVGSQYRL-EDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQ 219
Score = 54.4 bits (125), Expect = 2e-06
Identities = 34/111 (30%), Positives = 48/111 (43%), Gaps = 8/111 (7%)
Query: 369 YDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCK----YVNCGGLTPIEDGDVAL 424
Y+V I + C +G+ L G +R C+ +G WSG C Y + G+ PI V
Sbjct: 121 YNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGI-PIGTRKVG- 178
Query: 425 IDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPP 475
++ Y C TL G+ RTC + G W G P C + D P
Sbjct: 179 --SQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQDSFMYDTP 227
Score = 48.8 bits (111), Expect = 1e-04
Identities = 21/63 (33%), Positives = 31/63 (49%)
Query: 345 ICQYLPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPP 404
IC C +P + T +G+ Y + + Y C G L G + R C++ G WSG P
Sbjct: 157 ICDNGAGYCSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEP 216
Query: 405 SCK 407
SC+
Sbjct: 217 SCQ 219
Score = 32.7 bits (71), Expect = 7.4
Identities = 16/66 (24%), Positives = 28/66 (42%), Gaps = 3/66 (4%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTN 61
C +P +P R + ++ + Y C G L G+++R C G W+ P C +
Sbjct: 165 CSNPGIPIGTR-KVGSQYRLEDSV--TYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQDS 221
Query: 62 VAFRKP 67
+ P
Sbjct: 222 FMYDTP 227
>AL844853-12|CAI41860.1| 764|Homo sapiens B-factor, properdin
protein.
Length = 764
Score = 83.0 bits (196), Expect = 5e-15
Identities = 64/214 (29%), Positives = 87/214 (40%), Gaps = 25/214 (11%)
Query: 534 IHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWS---------YDIPSCE 584
I GSF L+ G ++ C ++ + C G WS C
Sbjct: 44 IKGGSFRLLQE----GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECR 99
Query: 585 LTSCPEP-EVPSGGYMEAFDYY-VHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCE 642
CP P + +G Y YY V I+FHC G+ L G N CQ +G WSG + C+
Sbjct: 100 AIHCPRPHDFENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICD 159
Query: 643 YID--CGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPR 700
C P +P GT ++ L + Y C+ L G RRTC E WS + P
Sbjct: 160 NGAGYCSN-PGIPIGTRKV-GSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPS 217
Query: 701 CEEIRCSD--PIVAEKSIVSVT----GNDRSHGH 728
C++ D VAE + S+T G D GH
Sbjct: 218 CQDSFMYDTPQEVAEAFLSSLTETIEGVDAEDGH 251
Score = 80.2 bits (189), Expect = 4e-14
Identities = 54/178 (30%), Positives = 71/178 (39%), Gaps = 20/178 (11%)
Query: 740 GNTYRI---GALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPT----------CQYVDCG 786
G ++R+ G ++Y C G+ TC G WS T T C+ + C
Sbjct: 46 GGSFRLLQEGQALEYVCPSGFYPYPVQTRTCRSTGSWS-TLKTQDQKTVRKAECRAIHCP 104
Query: 787 NPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEIT-- 844
P ENG+ S + C + + L G R CQ NG WS + IC
Sbjct: 105 RPHDFENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGY 164
Query: 845 CPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVC 902
C +P I G V S + Y C RG L+G Q RTC G W+GT P C
Sbjct: 165 CSNPGIPI----GTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSC 218
Score = 72.1 bits (169), Expect = 1e-11
Identities = 41/165 (24%), Positives = 63/165 (38%), Gaps = 12/165 (7%)
Query: 490 GSLASYTCENGHILSGSTSVTCTLGGAWSGVPPS---------CKYVNCGTP-TIHKGSF 539
G Y C +G + TC G+WS + C+ ++C P G +
Sbjct: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEY 114
Query: 540 VLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTS--CPEPEVPSGG 597
+ F C Y L G+ C +G+WS C+ + C P +P G
Sbjct: 115 WPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIGT 174
Query: 598 YMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCE 642
Y + ++ +HC G L G CQ+ G WSG P+C+
Sbjct: 175 RKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQ 219
Score = 70.1 bits (164), Expect = 4e-11
Identities = 43/165 (26%), Positives = 65/165 (39%), Gaps = 11/165 (6%)
Query: 372 GSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPS---------CKYVNCGGLTPIEDGDV 422
G + Y CP G ++R C+ G WS C+ ++C E+G+
Sbjct: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEY 114
Query: 423 ALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL--FDWCPDPPAVSNA 480
+ C + +TL G+ RTC G W G+ C +C +P
Sbjct: 115 WPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIGT 174
Query: 481 SVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCK 525
+ ++ +Y C G L GS TC GG+WSG PSC+
Sbjct: 175 RKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQ 219
Score = 67.3 bits (157), Expect = 3e-10
Identities = 52/201 (25%), Positives = 77/201 (38%), Gaps = 15/201 (7%)
Query: 667 GSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSH 726
G ++Y C + + RTC WS ++ D K+ R H
Sbjct: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWST-------LKTQDQKTVRKAECRAIHCPRPH 107
Query: 727 GHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVD-- 784
+ Y + + + C GY + G + TC+ NG+WSG T C
Sbjct: 108 D---FENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGY 164
Query: 785 CGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEIT 844
C NPG I G + S + Y C L G RR CQE G+WS P C++
Sbjct: 165 CSNPG-IPIGTRKVGSQYRLEDSVT-YHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQDSF 222
Query: 845 CPDPSAQIKAGSGLLVVTSTL 865
D ++ A + L +T T+
Sbjct: 223 MYDTPQEV-AEAFLSSLTETI 242
Score = 66.5 bits (155), Expect = 5e-10
Identities = 49/169 (28%), Positives = 69/169 (40%), Gaps = 15/169 (8%)
Query: 806 GATAFYQCDENWELEGVIRRMCQENGTWS---------LEPPICKEITCPDPSAQIKAGS 856
G Y C + V R C+ G+WS + C+ I CP P + G
Sbjct: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPH-DFENGE 113
Query: 857 GLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPID--CRSPGNIE 914
+ ++ E + C GY L+G RTC G+W+G +C C +PG I
Sbjct: 114 -YWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPG-IP 171
Query: 915 NGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
G + + L SV Y+C G R C + G WSG EPSC+
Sbjct: 172 IGTRKVGSQYRL-EDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQ 219
Score = 54.4 bits (125), Expect = 2e-06
Identities = 34/111 (30%), Positives = 48/111 (43%), Gaps = 8/111 (7%)
Query: 369 YDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCK----YVNCGGLTPIEDGDVAL 424
Y+V I + C +G+ L G +R C+ +G WSG C Y + G+ PI V
Sbjct: 121 YNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGI-PIGTRKVG- 178
Query: 425 IDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPP 475
++ Y C TL G+ RTC + G W G P C + D P
Sbjct: 179 --SQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQDSFMYDTP 227
Score = 48.8 bits (111), Expect = 1e-04
Identities = 21/63 (33%), Positives = 31/63 (49%)
Query: 345 ICQYLPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPP 404
IC C +P + T +G+ Y + + Y C G L G + R C++ G WSG P
Sbjct: 157 ICDNGAGYCSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEP 216
Query: 405 SCK 407
SC+
Sbjct: 217 SCQ 219
Score = 32.7 bits (71), Expect = 7.4
Identities = 16/66 (24%), Positives = 28/66 (42%), Gaps = 3/66 (4%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTN 61
C +P +P R + ++ + Y C G L G+++R C G W+ P C +
Sbjct: 165 CSNPGIPIGTR-KVGSQYRLEDSV--TYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQDS 221
Query: 62 VAFRKP 67
+ P
Sbjct: 222 FMYDTP 227
>AL844853-11|CAI41859.1| 621|Homo sapiens B-factor, properdin
protein.
Length = 621
Score = 83.0 bits (196), Expect = 5e-15
Identities = 64/214 (29%), Positives = 87/214 (40%), Gaps = 25/214 (11%)
Query: 534 IHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWS---------YDIPSCE 584
I GSF L+ G ++ C ++ + C G WS C
Sbjct: 44 IKGGSFRLLQE----GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECR 99
Query: 585 LTSCPEP-EVPSGGYMEAFDYY-VHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCE 642
CP P + +G Y YY V I+FHC G+ L G N CQ +G WSG + C+
Sbjct: 100 AIHCPRPHDFENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICD 159
Query: 643 YID--CGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPR 700
C P +P GT ++ L + Y C+ L G RRTC E WS + P
Sbjct: 160 NGAGYCSN-PGIPIGTRKV-GSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPS 217
Query: 701 CEEIRCSD--PIVAEKSIVSVT----GNDRSHGH 728
C++ D VAE + S+T G D GH
Sbjct: 218 CQDSFMYDTPQEVAEAFLSSLTETIEGVDAEDGH 251
Score = 80.2 bits (189), Expect = 4e-14
Identities = 54/178 (30%), Positives = 71/178 (39%), Gaps = 20/178 (11%)
Query: 740 GNTYRI---GALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPT----------CQYVDCG 786
G ++R+ G ++Y C G+ TC G WS T T C+ + C
Sbjct: 46 GGSFRLLQEGQALEYVCPSGFYPYPVQTRTCRSTGSWS-TLKTQDQKTVRKAECRAIHCP 104
Query: 787 NPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEIT-- 844
P ENG+ S + C + + L G R CQ NG WS + IC
Sbjct: 105 RPHDFENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGY 164
Query: 845 CPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVC 902
C +P I G V S + Y C RG L+G Q RTC G W+GT P C
Sbjct: 165 CSNPGIPI----GTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSC 218
Score = 72.1 bits (169), Expect = 1e-11
Identities = 41/165 (24%), Positives = 63/165 (38%), Gaps = 12/165 (7%)
Query: 490 GSLASYTCENGHILSGSTSVTCTLGGAWSGVPPS---------CKYVNCGTP-TIHKGSF 539
G Y C +G + TC G+WS + C+ ++C P G +
Sbjct: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEY 114
Query: 540 VLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTS--CPEPEVPSGG 597
+ F C Y L G+ C +G+WS C+ + C P +P G
Sbjct: 115 WPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIGT 174
Query: 598 YMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCE 642
Y + ++ +HC G L G CQ+ G WSG P+C+
Sbjct: 175 RKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQ 219
Score = 70.1 bits (164), Expect = 4e-11
Identities = 43/165 (26%), Positives = 65/165 (39%), Gaps = 11/165 (6%)
Query: 372 GSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPS---------CKYVNCGGLTPIEDGDV 422
G + Y CP G ++R C+ G WS C+ ++C E+G+
Sbjct: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEY 114
Query: 423 ALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL--FDWCPDPPAVSNA 480
+ C + +TL G+ RTC G W G+ C +C +P
Sbjct: 115 WPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIGT 174
Query: 481 SVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCK 525
+ ++ +Y C G L GS TC GG+WSG PSC+
Sbjct: 175 RKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQ 219
Score = 67.3 bits (157), Expect = 3e-10
Identities = 52/201 (25%), Positives = 77/201 (38%), Gaps = 15/201 (7%)
Query: 667 GSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSH 726
G ++Y C + + RTC WS ++ D K+ R H
Sbjct: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWST-------LKTQDQKTVRKAECRAIHCPRPH 107
Query: 727 GHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVD-- 784
+ Y + + + C GY + G + TC+ NG+WSG T C
Sbjct: 108 D---FENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGY 164
Query: 785 CGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEIT 844
C NPG I G + S + Y C L G RR CQE G+WS P C++
Sbjct: 165 CSNPG-IPIGTRKVGSQYRLEDSVT-YHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQDSF 222
Query: 845 CPDPSAQIKAGSGLLVVTSTL 865
D ++ A + L +T T+
Sbjct: 223 MYDTPQEV-AEAFLSSLTETI 242
Score = 66.5 bits (155), Expect = 5e-10
Identities = 49/169 (28%), Positives = 69/169 (40%), Gaps = 15/169 (8%)
Query: 806 GATAFYQCDENWELEGVIRRMCQENGTWS---------LEPPICKEITCPDPSAQIKAGS 856
G Y C + V R C+ G+WS + C+ I CP P + G
Sbjct: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPH-DFENGE 113
Query: 857 GLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPID--CRSPGNIE 914
+ ++ E + C GY L+G RTC G+W+G +C C +PG I
Sbjct: 114 -YWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPG-IP 171
Query: 915 NGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
G + + L SV Y+C G R C + G WSG EPSC+
Sbjct: 172 IGTRKVGSQYRL-EDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQ 219
Score = 54.4 bits (125), Expect = 2e-06
Identities = 34/111 (30%), Positives = 48/111 (43%), Gaps = 8/111 (7%)
Query: 369 YDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCK----YVNCGGLTPIEDGDVAL 424
Y+V I + C +G+ L G +R C+ +G WSG C Y + G+ PI V
Sbjct: 121 YNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGI-PIGTRKVG- 178
Query: 425 IDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPP 475
++ Y C TL G+ RTC + G W G P C + D P
Sbjct: 179 --SQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQDSFMYDTP 227
Score = 48.8 bits (111), Expect = 1e-04
Identities = 21/63 (33%), Positives = 31/63 (49%)
Query: 345 ICQYLPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPP 404
IC C +P + T +G+ Y + + Y C G L G + R C++ G WSG P
Sbjct: 157 ICDNGAGYCSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEP 216
Query: 405 SCK 407
SC+
Sbjct: 217 SCQ 219
Score = 32.7 bits (71), Expect = 7.4
Identities = 16/66 (24%), Positives = 28/66 (42%), Gaps = 3/66 (4%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTN 61
C +P +P R + ++ + Y C G L G+++R C G W+ P C +
Sbjct: 165 CSNPGIPIGTR-KVGSQYRLEDSV--TYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQDS 221
Query: 62 VAFRKP 67
+ P
Sbjct: 222 FMYDTP 227
>AL662849-6|CAI17456.1| 764|Homo sapiens complement factor B
protein.
Length = 764
Score = 83.0 bits (196), Expect = 5e-15
Identities = 64/214 (29%), Positives = 87/214 (40%), Gaps = 25/214 (11%)
Query: 534 IHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWS---------YDIPSCE 584
I GSF L+ G ++ C ++ + C G WS C
Sbjct: 44 IKGGSFRLLQE----GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECR 99
Query: 585 LTSCPEP-EVPSGGYMEAFDYY-VHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCE 642
CP P + +G Y YY V I+FHC G+ L G N CQ +G WSG + C+
Sbjct: 100 AIHCPRPHDFENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICD 159
Query: 643 YID--CGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPR 700
C P +P GT ++ L + Y C+ L G RRTC E WS + P
Sbjct: 160 NGAGYCSN-PGIPIGTRKV-GSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPS 217
Query: 701 CEEIRCSD--PIVAEKSIVSVT----GNDRSHGH 728
C++ D VAE + S+T G D GH
Sbjct: 218 CQDSFMYDTPQEVAEAFLSSLTETIEGVDAEDGH 251
Score = 80.2 bits (189), Expect = 4e-14
Identities = 54/178 (30%), Positives = 71/178 (39%), Gaps = 20/178 (11%)
Query: 740 GNTYRI---GALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPT----------CQYVDCG 786
G ++R+ G ++Y C G+ TC G WS T T C+ + C
Sbjct: 46 GGSFRLLQEGQALEYVCPSGFYPYPVQTRTCRSTGSWS-TLKTQDQKTVRKAECRAIHCP 104
Query: 787 NPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEIT-- 844
P ENG+ S + C + + L G R CQ NG WS + IC
Sbjct: 105 RPHDFENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGY 164
Query: 845 CPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVC 902
C +P I G V S + Y C RG L+G Q RTC G W+GT P C
Sbjct: 165 CSNPGIPI----GTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSC 218
Score = 72.1 bits (169), Expect = 1e-11
Identities = 41/165 (24%), Positives = 63/165 (38%), Gaps = 12/165 (7%)
Query: 490 GSLASYTCENGHILSGSTSVTCTLGGAWSGVPPS---------CKYVNCGTP-TIHKGSF 539
G Y C +G + TC G+WS + C+ ++C P G +
Sbjct: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEY 114
Query: 540 VLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTS--CPEPEVPSGG 597
+ F C Y L G+ C +G+WS C+ + C P +P G
Sbjct: 115 WPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIGT 174
Query: 598 YMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCE 642
Y + ++ +HC G L G CQ+ G WSG P+C+
Sbjct: 175 RKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQ 219
Score = 70.1 bits (164), Expect = 4e-11
Identities = 43/165 (26%), Positives = 65/165 (39%), Gaps = 11/165 (6%)
Query: 372 GSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPS---------CKYVNCGGLTPIEDGDV 422
G + Y CP G ++R C+ G WS C+ ++C E+G+
Sbjct: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEY 114
Query: 423 ALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL--FDWCPDPPAVSNA 480
+ C + +TL G+ RTC G W G+ C +C +P
Sbjct: 115 WPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIGT 174
Query: 481 SVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCK 525
+ ++ +Y C G L GS TC GG+WSG PSC+
Sbjct: 175 RKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQ 219
Score = 67.3 bits (157), Expect = 3e-10
Identities = 52/201 (25%), Positives = 77/201 (38%), Gaps = 15/201 (7%)
Query: 667 GSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSH 726
G ++Y C + + RTC WS ++ D K+ R H
Sbjct: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWST-------LKTQDQKTVRKAECRAIHCPRPH 107
Query: 727 GHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVD-- 784
+ Y + + + C GY + G + TC+ NG+WSG T C
Sbjct: 108 D---FENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGY 164
Query: 785 CGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEIT 844
C NPG I G + S + Y C L G RR CQE G+WS P C++
Sbjct: 165 CSNPG-IPIGTRKVGSQYRLEDSVT-YHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQDSF 222
Query: 845 CPDPSAQIKAGSGLLVVTSTL 865
D ++ A + L +T T+
Sbjct: 223 MYDTPQEV-AEAFLSSLTETI 242
Score = 66.5 bits (155), Expect = 5e-10
Identities = 49/169 (28%), Positives = 69/169 (40%), Gaps = 15/169 (8%)
Query: 806 GATAFYQCDENWELEGVIRRMCQENGTWS---------LEPPICKEITCPDPSAQIKAGS 856
G Y C + V R C+ G+WS + C+ I CP P + G
Sbjct: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPH-DFENGE 113
Query: 857 GLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPID--CRSPGNIE 914
+ ++ E + C GY L+G RTC G+W+G +C C +PG I
Sbjct: 114 -YWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPG-IP 171
Query: 915 NGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
G + + L SV Y+C G R C + G WSG EPSC+
Sbjct: 172 IGTRKVGSQYRL-EDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQ 219
Score = 54.4 bits (125), Expect = 2e-06
Identities = 34/111 (30%), Positives = 48/111 (43%), Gaps = 8/111 (7%)
Query: 369 YDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCK----YVNCGGLTPIEDGDVAL 424
Y+V I + C +G+ L G +R C+ +G WSG C Y + G+ PI V
Sbjct: 121 YNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGI-PIGTRKVG- 178
Query: 425 IDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPP 475
++ Y C TL G+ RTC + G W G P C + D P
Sbjct: 179 --SQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQDSFMYDTP 227
Score = 48.8 bits (111), Expect = 1e-04
Identities = 21/63 (33%), Positives = 31/63 (49%)
Query: 345 ICQYLPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPP 404
IC C +P + T +G+ Y + + Y C G L G + R C++ G WSG P
Sbjct: 157 ICDNGAGYCSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEP 216
Query: 405 SCK 407
SC+
Sbjct: 217 SCQ 219
Score = 32.7 bits (71), Expect = 7.4
Identities = 16/66 (24%), Positives = 28/66 (42%), Gaps = 3/66 (4%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTN 61
C +P +P R + ++ + Y C G L G+++R C G W+ P C +
Sbjct: 165 CSNPGIPIGTR-KVGSQYRLEDSV--TYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQDS 221
Query: 62 VAFRKP 67
+ P
Sbjct: 222 FMYDTP 227
>AL645922-7|CAI41725.2| 764|Homo sapiens complement factor B
protein.
Length = 764
Score = 83.0 bits (196), Expect = 5e-15
Identities = 64/214 (29%), Positives = 87/214 (40%), Gaps = 25/214 (11%)
Query: 534 IHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWS---------YDIPSCE 584
I GSF L+ G ++ C ++ + C G WS C
Sbjct: 44 IKGGSFRLLQE----GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECR 99
Query: 585 LTSCPEP-EVPSGGYMEAFDYY-VHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCE 642
CP P + +G Y YY V I+FHC G+ L G N CQ +G WSG + C+
Sbjct: 100 AIHCPRPHDFENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICD 159
Query: 643 YID--CGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPR 700
C P +P GT ++ L + Y C+ L G RRTC E WS + P
Sbjct: 160 NGAGYCSN-PGIPIGTRKV-GSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPS 217
Query: 701 CEEIRCSD--PIVAEKSIVSVT----GNDRSHGH 728
C++ D VAE + S+T G D GH
Sbjct: 218 CQDSFMYDTPQEVAEAFLSSLTETIEGVDAEDGH 251
Score = 80.2 bits (189), Expect = 4e-14
Identities = 54/178 (30%), Positives = 71/178 (39%), Gaps = 20/178 (11%)
Query: 740 GNTYRI---GALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPT----------CQYVDCG 786
G ++R+ G ++Y C G+ TC G WS T T C+ + C
Sbjct: 46 GGSFRLLQEGQALEYVCPSGFYPYPVQTRTCRSTGSWS-TLKTQDQKTVRKAECRAIHCP 104
Query: 787 NPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEIT-- 844
P ENG+ S + C + + L G R CQ NG WS + IC
Sbjct: 105 RPHDFENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGY 164
Query: 845 CPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVC 902
C +P I G V S + Y C RG L+G Q RTC G W+GT P C
Sbjct: 165 CSNPGIPI----GTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSC 218
Score = 72.1 bits (169), Expect = 1e-11
Identities = 41/165 (24%), Positives = 63/165 (38%), Gaps = 12/165 (7%)
Query: 490 GSLASYTCENGHILSGSTSVTCTLGGAWSGVPPS---------CKYVNCGTP-TIHKGSF 539
G Y C +G + TC G+WS + C+ ++C P G +
Sbjct: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEY 114
Query: 540 VLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTS--CPEPEVPSGG 597
+ F C Y L G+ C +G+WS C+ + C P +P G
Sbjct: 115 WPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIGT 174
Query: 598 YMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCE 642
Y + ++ +HC G L G CQ+ G WSG P+C+
Sbjct: 175 RKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQ 219
Score = 70.1 bits (164), Expect = 4e-11
Identities = 43/165 (26%), Positives = 65/165 (39%), Gaps = 11/165 (6%)
Query: 372 GSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPS---------CKYVNCGGLTPIEDGDV 422
G + Y CP G ++R C+ G WS C+ ++C E+G+
Sbjct: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEY 114
Query: 423 ALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL--FDWCPDPPAVSNA 480
+ C + +TL G+ RTC G W G+ C +C +P
Sbjct: 115 WPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIGT 174
Query: 481 SVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCK 525
+ ++ +Y C G L GS TC GG+WSG PSC+
Sbjct: 175 RKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQ 219
Score = 67.3 bits (157), Expect = 3e-10
Identities = 52/201 (25%), Positives = 77/201 (38%), Gaps = 15/201 (7%)
Query: 667 GSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSH 726
G ++Y C + + RTC WS ++ D K+ R H
Sbjct: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWST-------LKTQDQKTVRKAECRAIHCPRPH 107
Query: 727 GHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVD-- 784
+ Y + + + C GY + G + TC+ NG+WSG T C
Sbjct: 108 D---FENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGY 164
Query: 785 CGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEIT 844
C NPG I G + S + Y C L G RR CQE G+WS P C++
Sbjct: 165 CSNPG-IPIGTRKVGSQYRLEDSVT-YHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQDSF 222
Query: 845 CPDPSAQIKAGSGLLVVTSTL 865
D ++ A + L +T T+
Sbjct: 223 MYDTPQEV-AEAFLSSLTETI 242
Score = 66.5 bits (155), Expect = 5e-10
Identities = 49/169 (28%), Positives = 69/169 (40%), Gaps = 15/169 (8%)
Query: 806 GATAFYQCDENWELEGVIRRMCQENGTWS---------LEPPICKEITCPDPSAQIKAGS 856
G Y C + V R C+ G+WS + C+ I CP P + G
Sbjct: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPH-DFENGE 113
Query: 857 GLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPID--CRSPGNIE 914
+ ++ E + C GY L+G RTC G+W+G +C C +PG I
Sbjct: 114 -YWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPG-IP 171
Query: 915 NGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
G + + L SV Y+C G R C + G WSG EPSC+
Sbjct: 172 IGTRKVGSQYRL-EDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQ 219
Score = 54.4 bits (125), Expect = 2e-06
Identities = 34/111 (30%), Positives = 48/111 (43%), Gaps = 8/111 (7%)
Query: 369 YDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCK----YVNCGGLTPIEDGDVAL 424
Y+V I + C +G+ L G +R C+ +G WSG C Y + G+ PI V
Sbjct: 121 YNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGI-PIGTRKVG- 178
Query: 425 IDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPP 475
++ Y C TL G+ RTC + G W G P C + D P
Sbjct: 179 --SQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQDSFMYDTP 227
Score = 48.8 bits (111), Expect = 1e-04
Identities = 21/63 (33%), Positives = 31/63 (49%)
Query: 345 ICQYLPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPP 404
IC C +P + T +G+ Y + + Y C G L G + R C++ G WSG P
Sbjct: 157 ICDNGAGYCSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEP 216
Query: 405 SCK 407
SC+
Sbjct: 217 SCQ 219
Score = 32.7 bits (71), Expect = 7.4
Identities = 16/66 (24%), Positives = 28/66 (42%), Gaps = 3/66 (4%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTN 61
C +P +P R + ++ + Y C G L G+++R C G W+ P C +
Sbjct: 165 CSNPGIPIGTR-KVGSQYRLEDSV--TYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQDS 221
Query: 62 VAFRKP 67
+ P
Sbjct: 222 FMYDTP 227
>AK223400-1|BAD97120.1| 764|Homo sapiens complement factor B
preproprotein variant protein.
Length = 764
Score = 83.0 bits (196), Expect = 5e-15
Identities = 64/214 (29%), Positives = 87/214 (40%), Gaps = 25/214 (11%)
Query: 534 IHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWS---------YDIPSCE 584
I GSF L+ G ++ C ++ + C G WS C
Sbjct: 44 IKGGSFRLLQE----GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECR 99
Query: 585 LTSCPEP-EVPSGGYMEAFDYY-VHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCE 642
CP P + +G Y YY V I+FHC G+ L G N CQ +G WSG + C+
Sbjct: 100 AIHCPRPHDFENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICD 159
Query: 643 YID--CGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPR 700
C P +P GT ++ L + Y C+ L G RRTC E WS + P
Sbjct: 160 NGAGYCSN-PGIPIGTRKV-GSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPS 217
Query: 701 CEEIRCSD--PIVAEKSIVSVT----GNDRSHGH 728
C++ D VAE + S+T G D GH
Sbjct: 218 CQDSFMYDTPQEVAEAFLSSLTETIEGVDAEDGH 251
Score = 80.2 bits (189), Expect = 4e-14
Identities = 54/178 (30%), Positives = 71/178 (39%), Gaps = 20/178 (11%)
Query: 740 GNTYRI---GALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPT----------CQYVDCG 786
G ++R+ G ++Y C G+ TC G WS T T C+ + C
Sbjct: 46 GGSFRLLQEGQALEYVCPSGFYPYPVQTRTCRSTGSWS-TLKTQDQKTVRKAECRAIHCP 104
Query: 787 NPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEIT-- 844
P ENG+ S + C + + L G R CQ NG WS + IC
Sbjct: 105 RPHDFENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGY 164
Query: 845 CPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVC 902
C +P I G V S + Y C RG L+G Q RTC G W+GT P C
Sbjct: 165 CSNPGIPI----GTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSC 218
Score = 72.1 bits (169), Expect = 1e-11
Identities = 41/165 (24%), Positives = 63/165 (38%), Gaps = 12/165 (7%)
Query: 490 GSLASYTCENGHILSGSTSVTCTLGGAWSGVPPS---------CKYVNCGTP-TIHKGSF 539
G Y C +G + TC G+WS + C+ ++C P G +
Sbjct: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEY 114
Query: 540 VLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTS--CPEPEVPSGG 597
+ F C Y L G+ C +G+WS C+ + C P +P G
Sbjct: 115 WPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIGT 174
Query: 598 YMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCE 642
Y + ++ +HC G L G CQ+ G WSG P+C+
Sbjct: 175 RKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQ 219
Score = 70.1 bits (164), Expect = 4e-11
Identities = 43/165 (26%), Positives = 65/165 (39%), Gaps = 11/165 (6%)
Query: 372 GSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPS---------CKYVNCGGLTPIEDGDV 422
G + Y CP G ++R C+ G WS C+ ++C E+G+
Sbjct: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEY 114
Query: 423 ALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL--FDWCPDPPAVSNA 480
+ C + +TL G+ RTC G W G+ C +C +P
Sbjct: 115 WPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIGT 174
Query: 481 SVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCK 525
+ ++ +Y C G L GS TC GG+WSG PSC+
Sbjct: 175 RKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQ 219
Score = 67.3 bits (157), Expect = 3e-10
Identities = 52/201 (25%), Positives = 77/201 (38%), Gaps = 15/201 (7%)
Query: 667 GSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSH 726
G ++Y C + + RTC WS ++ D K+ R H
Sbjct: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWST-------LKTQDQKTVRKAECRAIHCPRPH 107
Query: 727 GHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVD-- 784
+ Y + + + C GY + G + TC+ NG+WSG T C
Sbjct: 108 D---FENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGY 164
Query: 785 CGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEIT 844
C NPG I G + S + Y C L G RR CQE G+WS P C++
Sbjct: 165 CSNPG-IPIGTRKVGSQYRLEDSVT-YHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQDSF 222
Query: 845 CPDPSAQIKAGSGLLVVTSTL 865
D ++ A + L +T T+
Sbjct: 223 MYDTPQEV-AEAFLSSLTETI 242
Score = 66.5 bits (155), Expect = 5e-10
Identities = 49/169 (28%), Positives = 69/169 (40%), Gaps = 15/169 (8%)
Query: 806 GATAFYQCDENWELEGVIRRMCQENGTWS---------LEPPICKEITCPDPSAQIKAGS 856
G Y C + V R C+ G+WS + C+ I CP P + G
Sbjct: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPH-DFENGE 113
Query: 857 GLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPID--CRSPGNIE 914
+ ++ E + C GY L+G RTC G+W+G +C C +PG I
Sbjct: 114 -YWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPG-IP 171
Query: 915 NGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
G + + L SV Y+C G R C + G WSG EPSC+
Sbjct: 172 IGTRKVGSQYRL-EDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQ 219
Score = 54.4 bits (125), Expect = 2e-06
Identities = 34/111 (30%), Positives = 48/111 (43%), Gaps = 8/111 (7%)
Query: 369 YDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCK----YVNCGGLTPIEDGDVAL 424
Y+V I + C +G+ L G +R C+ +G WSG C Y + G+ PI V
Sbjct: 121 YNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGI-PIGTRKVG- 178
Query: 425 IDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPP 475
++ Y C TL G+ RTC + G W G P C + D P
Sbjct: 179 --SQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQDSFMYDTP 227
Score = 48.8 bits (111), Expect = 1e-04
Identities = 21/63 (33%), Positives = 31/63 (49%)
Query: 345 ICQYLPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPP 404
IC C +P + T +G+ Y + + Y C G L G + R C++ G WSG P
Sbjct: 157 ICDNGAGYCSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEP 216
Query: 405 SCK 407
SC+
Sbjct: 217 SCQ 219
Score = 32.7 bits (71), Expect = 7.4
Identities = 16/66 (24%), Positives = 28/66 (42%), Gaps = 3/66 (4%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTN 61
C +P +P R + ++ + Y C G L G+++R C G W+ P C +
Sbjct: 165 CSNPGIPIGTR-KVGSQYRLEDSV--TYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQDS 221
Query: 62 VAFRKP 67
+ P
Sbjct: 222 FMYDTP 227
>AF551848-1|AAN71991.1| 764|Homo sapiens B-factor, properdin
protein.
Length = 764
Score = 83.0 bits (196), Expect = 5e-15
Identities = 64/214 (29%), Positives = 87/214 (40%), Gaps = 25/214 (11%)
Query: 534 IHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWS---------YDIPSCE 584
I GSF L+ G ++ C ++ + C G WS C
Sbjct: 44 IKGGSFRLLQE----GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECR 99
Query: 585 LTSCPEP-EVPSGGYMEAFDYY-VHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCE 642
CP P + +G Y YY V I+FHC G+ L G N CQ +G WSG + C+
Sbjct: 100 AIHCPRPHDFENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICD 159
Query: 643 YID--CGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPR 700
C P +P GT ++ L + Y C+ L G RRTC E WS + P
Sbjct: 160 NGAGYCSN-PGIPIGTRKV-GSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPS 217
Query: 701 CEEIRCSD--PIVAEKSIVSVT----GNDRSHGH 728
C++ D VAE + S+T G D GH
Sbjct: 218 CQDSFMYDTPQEVAEAFLSSLTETIEGVDAEDGH 251
Score = 80.2 bits (189), Expect = 4e-14
Identities = 54/178 (30%), Positives = 71/178 (39%), Gaps = 20/178 (11%)
Query: 740 GNTYRI---GALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPT----------CQYVDCG 786
G ++R+ G ++Y C G+ TC G WS T T C+ + C
Sbjct: 46 GGSFRLLQEGQALEYVCPSGFYPYPVQTRTCRSTGSWS-TLKTQDQKTVRKAECRAIHCP 104
Query: 787 NPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEIT-- 844
P ENG+ S + C + + L G R CQ NG WS + IC
Sbjct: 105 RPHDFENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGY 164
Query: 845 CPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVC 902
C +P I G V S + Y C RG L+G Q RTC G W+GT P C
Sbjct: 165 CSNPGIPI----GTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSC 218
Score = 72.1 bits (169), Expect = 1e-11
Identities = 41/165 (24%), Positives = 63/165 (38%), Gaps = 12/165 (7%)
Query: 490 GSLASYTCENGHILSGSTSVTCTLGGAWSGVPPS---------CKYVNCGTP-TIHKGSF 539
G Y C +G + TC G+WS + C+ ++C P G +
Sbjct: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEY 114
Query: 540 VLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTS--CPEPEVPSGG 597
+ F C Y L G+ C +G+WS C+ + C P +P G
Sbjct: 115 WPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIGT 174
Query: 598 YMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCE 642
Y + ++ +HC G L G CQ+ G WSG P+C+
Sbjct: 175 RKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQ 219
Score = 70.1 bits (164), Expect = 4e-11
Identities = 43/165 (26%), Positives = 65/165 (39%), Gaps = 11/165 (6%)
Query: 372 GSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPS---------CKYVNCGGLTPIEDGDV 422
G + Y CP G ++R C+ G WS C+ ++C E+G+
Sbjct: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEY 114
Query: 423 ALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL--FDWCPDPPAVSNA 480
+ C + +TL G+ RTC G W G+ C +C +P
Sbjct: 115 WPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIGT 174
Query: 481 SVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCK 525
+ ++ +Y C G L GS TC GG+WSG PSC+
Sbjct: 175 RKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQ 219
Score = 67.3 bits (157), Expect = 3e-10
Identities = 52/201 (25%), Positives = 77/201 (38%), Gaps = 15/201 (7%)
Query: 667 GSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSH 726
G ++Y C + + RTC WS ++ D K+ R H
Sbjct: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWST-------LKTQDQKTVRKAECRAIHCPRPH 107
Query: 727 GHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVD-- 784
+ Y + + + C GY + G + TC+ NG+WSG T C
Sbjct: 108 D---FENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGY 164
Query: 785 CGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEIT 844
C NPG I G + S + Y C L G RR CQE G+WS P C++
Sbjct: 165 CSNPG-IPIGTRKVGSQYRLEDSVT-YHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQDSF 222
Query: 845 CPDPSAQIKAGSGLLVVTSTL 865
D ++ A + L +T T+
Sbjct: 223 MYDTPQEV-AEAFLSSLTETI 242
Score = 66.5 bits (155), Expect = 5e-10
Identities = 49/169 (28%), Positives = 69/169 (40%), Gaps = 15/169 (8%)
Query: 806 GATAFYQCDENWELEGVIRRMCQENGTWS---------LEPPICKEITCPDPSAQIKAGS 856
G Y C + V R C+ G+WS + C+ I CP P + G
Sbjct: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPH-DFENGE 113
Query: 857 GLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPID--CRSPGNIE 914
+ ++ E + C GY L+G RTC G+W+G +C C +PG I
Sbjct: 114 -YWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPG-IP 171
Query: 915 NGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
G + + L SV Y+C G R C + G WSG EPSC+
Sbjct: 172 IGTRKVGSQYRL-EDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQ 219
Score = 54.4 bits (125), Expect = 2e-06
Identities = 34/111 (30%), Positives = 48/111 (43%), Gaps = 8/111 (7%)
Query: 369 YDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCK----YVNCGGLTPIEDGDVAL 424
Y+V I + C +G+ L G +R C+ +G WSG C Y + G+ PI V
Sbjct: 121 YNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGI-PIGTRKVG- 178
Query: 425 IDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPP 475
++ Y C TL G+ RTC + G W G P C + D P
Sbjct: 179 --SQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQDSFMYDTP 227
Score = 48.8 bits (111), Expect = 1e-04
Identities = 21/63 (33%), Positives = 31/63 (49%)
Query: 345 ICQYLPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPP 404
IC C +P + T +G+ Y + + Y C G L G + R C++ G WSG P
Sbjct: 157 ICDNGAGYCSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEP 216
Query: 405 SCK 407
SC+
Sbjct: 217 SCQ 219
Score = 32.7 bits (71), Expect = 7.4
Identities = 16/66 (24%), Positives = 28/66 (42%), Gaps = 3/66 (4%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTN 61
C +P +P R + ++ + Y C G L G+++R C G W+ P C +
Sbjct: 165 CSNPGIPIGTR-KVGSQYRLEDSV--TYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQDS 221
Query: 62 VAFRKP 67
+ P
Sbjct: 222 FMYDTP 227
>AF349679-1|AAK30167.1| 621|Homo sapiens factor B protein.
Length = 621
Score = 83.0 bits (196), Expect = 5e-15
Identities = 64/214 (29%), Positives = 87/214 (40%), Gaps = 25/214 (11%)
Query: 534 IHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWS---------YDIPSCE 584
I GSF L+ G ++ C ++ + C G WS C
Sbjct: 44 IKGGSFRLLQE----GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECR 99
Query: 585 LTSCPEP-EVPSGGYMEAFDYY-VHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCE 642
CP P + +G Y YY V I+FHC G+ L G N CQ +G WSG + C+
Sbjct: 100 AIHCPRPHDFENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICD 159
Query: 643 YID--CGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPR 700
C P +P GT ++ L + Y C+ L G RRTC E WS + P
Sbjct: 160 NGAGYCSN-PGIPIGTRKV-GSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPS 217
Query: 701 CEEIRCSD--PIVAEKSIVSVT----GNDRSHGH 728
C++ D VAE + S+T G D GH
Sbjct: 218 CQDSFMYDTPQEVAEAFLSSLTETIEGVDAEDGH 251
Score = 80.2 bits (189), Expect = 4e-14
Identities = 54/178 (30%), Positives = 71/178 (39%), Gaps = 20/178 (11%)
Query: 740 GNTYRI---GALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPT----------CQYVDCG 786
G ++R+ G ++Y C G+ TC G WS T T C+ + C
Sbjct: 46 GGSFRLLQEGQALEYVCPSGFYPYPVQTRTCRSTGSWS-TLKTQDQKTVRKAECRAIHCP 104
Query: 787 NPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEIT-- 844
P ENG+ S + C + + L G R CQ NG WS + IC
Sbjct: 105 RPHDFENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGY 164
Query: 845 CPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVC 902
C +P I G V S + Y C RG L+G Q RTC G W+GT P C
Sbjct: 165 CSNPGIPI----GTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSC 218
Score = 72.1 bits (169), Expect = 1e-11
Identities = 41/165 (24%), Positives = 63/165 (38%), Gaps = 12/165 (7%)
Query: 490 GSLASYTCENGHILSGSTSVTCTLGGAWSGVPPS---------CKYVNCGTP-TIHKGSF 539
G Y C +G + TC G+WS + C+ ++C P G +
Sbjct: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEY 114
Query: 540 VLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTS--CPEPEVPSGG 597
+ F C Y L G+ C +G+WS C+ + C P +P G
Sbjct: 115 WPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIGT 174
Query: 598 YMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCE 642
Y + ++ +HC G L G CQ+ G WSG P+C+
Sbjct: 175 RKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQ 219
Score = 70.1 bits (164), Expect = 4e-11
Identities = 43/165 (26%), Positives = 65/165 (39%), Gaps = 11/165 (6%)
Query: 372 GSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPS---------CKYVNCGGLTPIEDGDV 422
G + Y CP G ++R C+ G WS C+ ++C E+G+
Sbjct: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEY 114
Query: 423 ALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL--FDWCPDPPAVSNA 480
+ C + +TL G+ RTC G W G+ C +C +P
Sbjct: 115 WPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIGT 174
Query: 481 SVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCK 525
+ ++ +Y C G L GS TC GG+WSG PSC+
Sbjct: 175 RKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQ 219
Score = 67.3 bits (157), Expect = 3e-10
Identities = 52/201 (25%), Positives = 77/201 (38%), Gaps = 15/201 (7%)
Query: 667 GSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSH 726
G ++Y C + + RTC WS ++ D K+ R H
Sbjct: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWST-------LKTQDQKTVRKAECRAIHCPRPH 107
Query: 727 GHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVD-- 784
+ Y + + + C GY + G + TC+ NG+WSG T C
Sbjct: 108 D---FENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGY 164
Query: 785 CGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEIT 844
C NPG I G + S + Y C L G RR CQE G+WS P C++
Sbjct: 165 CSNPG-IPIGTRKVGSQYRLEDSVT-YHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQDSF 222
Query: 845 CPDPSAQIKAGSGLLVVTSTL 865
D ++ A + L +T T+
Sbjct: 223 MYDTPQEV-AEAFLSSLTETI 242
Score = 66.5 bits (155), Expect = 5e-10
Identities = 49/169 (28%), Positives = 69/169 (40%), Gaps = 15/169 (8%)
Query: 806 GATAFYQCDENWELEGVIRRMCQENGTWS---------LEPPICKEITCPDPSAQIKAGS 856
G Y C + V R C+ G+WS + C+ I CP P + G
Sbjct: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPH-DFENGE 113
Query: 857 GLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPID--CRSPGNIE 914
+ ++ E + C GY L+G RTC G+W+G +C C +PG I
Sbjct: 114 -YWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPG-IP 171
Query: 915 NGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
G + + L SV Y+C G R C + G WSG EPSC+
Sbjct: 172 IGTRKVGSQYRL-EDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQ 219
Score = 54.4 bits (125), Expect = 2e-06
Identities = 34/111 (30%), Positives = 48/111 (43%), Gaps = 8/111 (7%)
Query: 369 YDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCK----YVNCGGLTPIEDGDVAL 424
Y+V I + C +G+ L G +R C+ +G WSG C Y + G+ PI V
Sbjct: 121 YNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGI-PIGTRKVG- 178
Query: 425 IDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPP 475
++ Y C TL G+ RTC + G W G P C + D P
Sbjct: 179 --SQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQDSFMYDTP 227
Score = 48.8 bits (111), Expect = 1e-04
Identities = 21/63 (33%), Positives = 31/63 (49%)
Query: 345 ICQYLPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPP 404
IC C +P + T +G+ Y + + Y C G L G + R C++ G WSG P
Sbjct: 157 ICDNGAGYCSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEP 216
Query: 405 SCK 407
SC+
Sbjct: 217 SCQ 219
Score = 32.7 bits (71), Expect = 7.4
Identities = 16/66 (24%), Positives = 28/66 (42%), Gaps = 3/66 (4%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTN 61
C +P +P R + ++ + Y C G L G+++R C G W+ P C +
Sbjct: 165 CSNPGIPIGTR-KVGSQYRLEDSV--TYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQDS 221
Query: 62 VAFRKP 67
+ P
Sbjct: 222 FMYDTP 227
>AF019413-8|AAB67977.1| 764|Homo sapiens complement factor B
protein.
Length = 764
Score = 83.0 bits (196), Expect = 5e-15
Identities = 64/214 (29%), Positives = 87/214 (40%), Gaps = 25/214 (11%)
Query: 534 IHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWS---------YDIPSCE 584
I GSF L+ G ++ C ++ + C G WS C
Sbjct: 44 IKGGSFRLLQE----GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECR 99
Query: 585 LTSCPEP-EVPSGGYMEAFDYY-VHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCE 642
CP P + +G Y YY V I+FHC G+ L G N CQ +G WSG + C+
Sbjct: 100 AIHCPRPHDFENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICD 159
Query: 643 YID--CGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPR 700
C P +P GT ++ L + Y C+ L G RRTC E WS + P
Sbjct: 160 NGAGYCSN-PGIPIGTRKV-GSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPS 217
Query: 701 CEEIRCSD--PIVAEKSIVSVT----GNDRSHGH 728
C++ D VAE + S+T G D GH
Sbjct: 218 CQDSFMYDTPQEVAEAFLSSLTETIEGVDAEDGH 251
Score = 80.2 bits (189), Expect = 4e-14
Identities = 54/178 (30%), Positives = 71/178 (39%), Gaps = 20/178 (11%)
Query: 740 GNTYRI---GALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPT----------CQYVDCG 786
G ++R+ G ++Y C G+ TC G WS T T C+ + C
Sbjct: 46 GGSFRLLQEGQALEYVCPSGFYPYPVQTRTCRSTGSWS-TLKTQDQKTVRKAECRAIHCP 104
Query: 787 NPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEIT-- 844
P ENG+ S + C + + L G R CQ NG WS + IC
Sbjct: 105 RPHDFENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGY 164
Query: 845 CPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVC 902
C +P I G V S + Y C RG L+G Q RTC G W+GT P C
Sbjct: 165 CSNPGIPI----GTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSC 218
Score = 72.1 bits (169), Expect = 1e-11
Identities = 41/165 (24%), Positives = 63/165 (38%), Gaps = 12/165 (7%)
Query: 490 GSLASYTCENGHILSGSTSVTCTLGGAWSGVPPS---------CKYVNCGTP-TIHKGSF 539
G Y C +G + TC G+WS + C+ ++C P G +
Sbjct: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEY 114
Query: 540 VLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTS--CPEPEVPSGG 597
+ F C Y L G+ C +G+WS C+ + C P +P G
Sbjct: 115 WPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIGT 174
Query: 598 YMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCE 642
Y + ++ +HC G L G CQ+ G WSG P+C+
Sbjct: 175 RKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQ 219
Score = 70.1 bits (164), Expect = 4e-11
Identities = 43/165 (26%), Positives = 65/165 (39%), Gaps = 11/165 (6%)
Query: 372 GSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPS---------CKYVNCGGLTPIEDGDV 422
G + Y CP G ++R C+ G WS C+ ++C E+G+
Sbjct: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEY 114
Query: 423 ALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCL--FDWCPDPPAVSNA 480
+ C + +TL G+ RTC G W G+ C +C +P
Sbjct: 115 WPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIGT 174
Query: 481 SVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCK 525
+ ++ +Y C G L GS TC GG+WSG PSC+
Sbjct: 175 RKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQ 219
Score = 67.3 bits (157), Expect = 3e-10
Identities = 52/201 (25%), Positives = 77/201 (38%), Gaps = 15/201 (7%)
Query: 667 GSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSH 726
G ++Y C + + RTC WS ++ D K+ R H
Sbjct: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWST-------LKTQDQKTVRKAECRAIHCPRPH 107
Query: 727 GHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVD-- 784
+ Y + + + C GY + G + TC+ NG+WSG T C
Sbjct: 108 D---FENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGY 164
Query: 785 CGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEIT 844
C NPG I G + S + Y C L G RR CQE G+WS P C++
Sbjct: 165 CSNPG-IPIGTRKVGSQYRLEDSVT-YHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQDSF 222
Query: 845 CPDPSAQIKAGSGLLVVTSTL 865
D ++ A + L +T T+
Sbjct: 223 MYDTPQEV-AEAFLSSLTETI 242
Score = 66.5 bits (155), Expect = 5e-10
Identities = 49/169 (28%), Positives = 69/169 (40%), Gaps = 15/169 (8%)
Query: 806 GATAFYQCDENWELEGVIRRMCQENGTWS---------LEPPICKEITCPDPSAQIKAGS 856
G Y C + V R C+ G+WS + C+ I CP P + G
Sbjct: 55 GQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPH-DFENGE 113
Query: 857 GLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPID--CRSPGNIE 914
+ ++ E + C GY L+G RTC G+W+G +C C +PG I
Sbjct: 114 -YWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPG-IP 171
Query: 915 NGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCE 963
G + + L SV Y+C G R C + G WSG EPSC+
Sbjct: 172 IGTRKVGSQYRL-EDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQ 219
Score = 54.4 bits (125), Expect = 2e-06
Identities = 34/111 (30%), Positives = 48/111 (43%), Gaps = 8/111 (7%)
Query: 369 YDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCK----YVNCGGLTPIEDGDVAL 424
Y+V I + C +G+ L G +R C+ +G WSG C Y + G+ PI V
Sbjct: 121 YNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGI-PIGTRKVG- 178
Query: 425 IDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPP 475
++ Y C TL G+ RTC + G W G P C + D P
Sbjct: 179 --SQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQDSFMYDTP 227
Score = 48.8 bits (111), Expect = 1e-04
Identities = 21/63 (33%), Positives = 31/63 (49%)
Query: 345 ICQYLPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPP 404
IC C +P + T +G+ Y + + Y C G L G + R C++ G WSG P
Sbjct: 157 ICDNGAGYCSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEP 216
Query: 405 SCK 407
SC+
Sbjct: 217 SCQ 219
Score = 32.7 bits (71), Expect = 7.4
Identities = 16/66 (24%), Positives = 28/66 (42%), Gaps = 3/66 (4%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFCGTN 61
C +P +P R + ++ + Y C G L G+++R C G W+ P C +
Sbjct: 165 CSNPGIPIGTR-KVGSQYRLEDSV--TYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQDS 221
Query: 62 VAFRKP 67
+ P
Sbjct: 222 FMYDTP 227
>AJ640130-1|CAG26679.2| 578|Homo sapiens complement factor
H-related protein 4A precursor protein.
Length = 578
Score = 81.0 bits (191), Expect = 2e-14
Identities = 128/502 (25%), Positives = 187/502 (37%), Gaps = 65/502 (12%)
Query: 489 AGSLASYTCENGHIL-SGS--TSVTCTLGGAWSGVPPSCKYVNCGTPTIHKGSFVLINGT 545
AG SY C+ + SGS + CT G WS P + + I G +
Sbjct: 48 AGQSYSYYCDQNFVTPSGSYWDYIHCTQDG-WSPTVPCLRTCSKSDVEIENGFISESSSI 106
Query: 546 TTYGSIAQFTCEPDYWL---NGAEELVCNRDGKWSYDIPSCELTSCPEPEVP-SGGYMEA 601
Q+ C+P Y N + + C ++G WS P C + C P S
Sbjct: 107 YILNEETQYNCKPGYATADGNSSGSITCLQNG-WSTQ-PIC-IKFCDMPVFENSRAKSNG 163
Query: 602 FDYYVHSTINFHCEAGHKL-IGEP--NLVCQQDGEWSGDSPTC--EYIDCGKLPTLPYGT 656
+ +H T+++ C G++ G ++VC +DG WS PTC +CG P + G
Sbjct: 164 MWFKLHDTLDYECYDGYESSYGNTTDSIVCGEDG-WS-HLPTCYNSSENCGPPPPISNGD 221
Query: 657 MELLNGTTHLG-SVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIR-CSDPIVAEK 714
+L S ++Y C + Y L G TC+ WS+ PRC ++ C P +
Sbjct: 222 TTSFPQKVYLPWSRVEYQCQSYYELQGSKYVTCSNG-DWSE-PPRCISMKPCEFPEI--- 276
Query: 715 SIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGES---LSTCEDNG 771
HGH + + R G Y C++ + S C +G
Sbjct: 277 ----------QHGH--LYYENTRRPYFPVATGQSYSYYCDQNFVTPSGSYWDYIHCTQDG 324
Query: 772 QWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENW-----ELEGVIRRM 826
W T P C + IENG ++ S+ Y+C + G I
Sbjct: 325 -WLPTVP-CLRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSI--T 380
Query: 827 CQENGTWSLEPPICKEITCP-DPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQ 885
C +NG WS +P K P +++ K+ + TL Y+C GY +
Sbjct: 381 CLQNG-WSAQPICIKFCDMPVFENSRAKSNGMRFKLHDTLD------YECYDGYEISYGN 433
Query: 886 TRTCISKGQ--WNGTVPVCIPID--CRSPGNIENGKIVISNGSTLFGSS-VEYYCLSQYQ 940
T I G+ W+ P C C P I NG S VEY C S Y+
Sbjct: 434 TTGSIVCGEDGWS-HFPTCYNSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQSYYE 492
Query: 941 RVGPFLRKCLDDGRWSGEEPSC 962
G C +G WS E P C
Sbjct: 493 LQGSNYVTC-SNGEWS-EPPRC 512
Score = 73.7 bits (173), Expect = 3e-12
Identities = 123/535 (22%), Positives = 199/535 (37%), Gaps = 66/535 (12%)
Query: 437 YSCRENFTLVGNPERT---CGDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNG--HKAGS 491
Y C +NF C +G W P CL + N ++ + +
Sbjct: 54 YYCDQNFVTPSGSYWDYIHCTQDG-WSPTVP-CLRTCSKSDVEIENGFISESSSIYILNE 111
Query: 492 LASYTCENGHILS---GSTSVTCTLGGAWSGVPPSCKYVNCGTPTIHKGSFVLINGTT-T 547
Y C+ G+ + S S+TC G WS P K+ C P + + S NG
Sbjct: 112 ETQYNCKPGYATADGNSSGSITCLQNG-WSTQPICIKF--CDMP-VFENSRAKSNGMWFK 167
Query: 548 YGSIAQFTCEPDY---WLNGAEELVCNRDGKWSYDIPSCELTS--CPEPEVPSGGYMEAF 602
+ C Y + N + +VC DG WS+ +P+C +S C P S G +F
Sbjct: 168 LHDTLDYECYDGYESSYGNTTDSIVCGEDG-WSH-LPTCYNSSENCGPPPPISNGDTTSF 225
Query: 603 DYYVH---STINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMEL 659
V+ S + + C++ ++L G + C +G+WS + P C + + P + +G +
Sbjct: 226 PQKVYLPWSRVEYQCQSYYELQGSKYVTCS-NGDWS-EPPRCISMKPCEFPEIQHGHLYY 283
Query: 660 LNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDP--IVAEKSIV 717
N V + Y C + F + S + I C+ + +
Sbjct: 284 ENTRRPYFPVATGQSYSYY---------CDQNFV-TPSGSYWDYIHCTQDGWLPTVPCLR 333
Query: 718 SVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLS---TCEDNGQWS 774
+ + +D + I S + Y + ++Y+C+ GY + S TC NG WS
Sbjct: 334 TCSKSDIEIENGFISESSS-----IYILNKEIQYKCKPGYATADGNSSGSITCLQNG-WS 387
Query: 775 GTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELE-----GVIRRMCQE 829
P C C P EN + T Y+C + +E+ G I +C E
Sbjct: 388 AQ-PICIKF-CDMPV-FENSRAKSNGMRFKLHDTLDYECYDGYEISYGNTTGSI--VCGE 442
Query: 830 NGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTC 889
+G WS P P I G + YQC+ Y L+G TC
Sbjct: 443 DG-WSHFPTCYNSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQSYYELQGSNYVTC 501
Query: 890 ISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTL-----FGSSVEYYCLSQY 939
S G+W+ P CI + N+ I + S + G ++E+ C Y
Sbjct: 502 -SNGEWS-EPPRCIHPCIITEENMNKNNIQLKGKSDIKYYAKTGDTIEFMCKLGY 554
Score = 68.9 bits (161), Expect = 9e-11
Identities = 116/502 (23%), Positives = 185/502 (36%), Gaps = 71/502 (14%)
Query: 311 QPNNYNGEQNCVVLDGGRGWLWNDVGCNLDYLHWICQYLPPTCGSPDKLLNTTILGND-- 368
Q +Y +QN V G W+ + C D L TC D + +
Sbjct: 50 QSYSYYCDQNFVTPSGS---YWDYIHCTQDGWSPTVPCLR-TCSKSDVEIENGFISESSS 105
Query: 369 -YDVGSRIVYKCPEGHMLLGDKSRH---CKKDGFWSGAPPSCKYVNCGGLTPIEDGDVAL 424
Y + Y C G+ S C ++G WS P K+ + P+ + A
Sbjct: 106 IYILNEETQYNCKPGYATADGNSSGSITCLQNG-WSTQPICIKFCDM----PVFENSRAK 160
Query: 425 IDNRTTHGARAL-YSCRENF-TLVGNPERT--CGDEGIWDGEAPRCL--FDWCPDPPAVS 478
+ L Y C + + + GN + CG++G W P C + C PP +S
Sbjct: 161 SNGMWFKLHDTLDYECYDGYESSYGNTTDSIVCGEDG-WS-HLPTCYNSSENCGPPPPIS 218
Query: 479 NASVTVNGHKA---GSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTIH 535
N T K S Y C++ + L GS VTC+ G WS P C P I
Sbjct: 219 NGDTTSFPQKVYLPWSRVEYQCQSYYELQGSKYVTCS-NGDWSEPPRCISMKPCEFPEIQ 277
Query: 536 KGSFVLINGTTTYGSIA-----QFTCEPDYWL-NGA--EELVCNRDGKWSYDIPSCELTS 587
G N Y +A + C+ ++ +G+ + + C +DG W +P S
Sbjct: 278 HGHLYYENTRRPYFPVATGQSYSYYCDQNFVTPSGSYWDYIHCTQDG-WLPTVPCLRTCS 336
Query: 588 CPEPEVPSGGYMEAFDYYV-HSTINFHCEAGHKLI---GEPNLVCQQDGEWSGDSPTCEY 643
+ E+ +G E+ Y+ + I + C+ G+ ++ C Q+G WS P C
Sbjct: 337 KSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQNG-WSA-QPIC-- 392
Query: 644 IDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRL-VGPVRRT--CTEEFQWSDSSPR 700
I +P + L + Y C Y + G + C E+ WS P
Sbjct: 393 IKFCDMPVFENSRAKSNGMRFKLHDTLDYECYDGYEISYGNTTGSIVCGED-GWS-HFPT 450
Query: 701 C--EEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYK 758
C +C P ++ D + + +R V+Y+C+ Y+
Sbjct: 451 CYNSSEKCGPP-------PPISNGDTTSFLLKVYVPQSR-----------VEYQCQSYYE 492
Query: 759 VIGESLSTCEDNGQWSGTTPTC 780
+ G + TC NG+WS P C
Sbjct: 493 LQGSNYVTC-SNGEWS-EPPRC 512
Score = 33.1 bits (72), Expect = 5.6
Identities = 18/57 (31%), Positives = 28/57 (49%), Gaps = 2/57 (3%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
CG P N + ++ + + Y+C YEL G++ C+ GDW+ EPP C
Sbjct: 211 CGPPPPISNGDTTSFPQKVYLPWSRVEYQCQSYYELQGSKYVTCS-NGDWS-EPPRC 265
>M65292-1|AAA35946.1| 330|Homo sapiens factor H homologue protein.
Length = 330
Score = 80.6 bits (190), Expect = 3e-14
Identities = 87/289 (30%), Positives = 122/289 (42%), Gaps = 46/289 (15%)
Query: 667 GSVIQYSCTTNYRLVGP-----VRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTG 721
G V YSC Y V P R TCTEE WS + P+C + C P V
Sbjct: 48 GEVFYYSC--EYNFVSPSKSFWTRITCTEE-GWSPT-PKCLRL-CFFPFV---------- 92
Query: 722 NDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIG-ESLSTCEDNGQWSGTTPTC 780
+GH+ G T+ G V+ C GY++ E+ +C + G WS T P C
Sbjct: 93 ---ENGHS-------ESSGQTHLEGDTVQIICNTGYRLQNNENNISCVERG-WS-TPPKC 140
Query: 781 QYVD--CGNPGRIENGKVTLPSNATF-YGATAFYQCDENWELEGVIRRMCQENGTWSLEP 837
+ D C NP ++N + + + G YQC +E+ G MC NG W+ EP
Sbjct: 141 RSTDTSCVNPPTVQNAYIVSRQMSKYPSGERVRYQCRSPYEMFGDEEVMCL-NGNWT-EP 198
Query: 838 PICKEITCP-DPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWN 896
P CK+ T P I G S + YQC+ Y L+G++ TC GQW+
Sbjct: 199 PQCKDSTGKCGPPPPIDNGDITSFPLSVYAPASSVEYQCQNLYQLEGNKRITC-RNGQWS 257
Query: 897 GTVPVCIPIDCRSPGNIENGKIVI--SNGSTLF---GSSVEYYCLSQYQ 940
P C+ S +EN I + + L+ G S E+ C Y+
Sbjct: 258 -EPPKCLHPCVISREIMENYNIALRWTAKQKLYLRTGESAEFVCKRGYR 305
Score = 76.6 bits (180), Expect = 5e-13
Identities = 81/290 (27%), Positives = 118/290 (40%), Gaps = 45/290 (15%)
Query: 626 LVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHL-GSVIQYSCTTNYRLVGPV 684
+ C ++G WS PT + + P + G E +G THL G +Q C T YRL
Sbjct: 70 ITCTEEG-WS---PTPKCLRLCFFPFVENGHSES-SGQTHLEGDTVQIICNTGYRLQNNE 124
Query: 685 RRTCTEEFQWSDSSPRCE--EIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNT 742
E WS + P+C + C +P + + + +R +
Sbjct: 125 NNISCVERGWS-TPPKCRSTDTSCVNPPTVQNAYIV-----------------SRQMSK- 165
Query: 743 YRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVD--CGNPGRIENGKVT-LP 799
Y G V+Y+C Y++ G+ C NG W+ P C+ CG P I+NG +T P
Sbjct: 166 YPSGERVRYQCRSPYEMFGDEEVMCL-NGNWT-EPPQCKDSTGKCGPPPPIDNGDITSFP 223
Query: 800 SNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLL 859
+ ++ YQC ++LEG R C+ NG WS EPP C L
Sbjct: 224 LSVYAPASSVEYQCQNLYQLEGNKRITCR-NGQWS-EPPKCLHPCVISREIMENYNIALR 281
Query: 860 VVTST---LSIGGEAHYQCERGYNL--KGHQTRTCISKGQWNGTV--PVC 902
L G A + C+RGY L + H RT W+G + P C
Sbjct: 282 WTAKQKLYLRTGESAEFVCKRGYRLSSRSHTLRTTC----WDGKLEYPTC 327
Score = 68.5 bits (160), Expect = 1e-10
Identities = 57/223 (25%), Positives = 89/223 (39%), Gaps = 19/223 (8%)
Query: 490 GSLASYTCENGHILSGS---TSVTCTLGGAWSGVPPSCKYVNCGTPTIHKGSFVLINGTT 546
G + Y+CE + T +TCT G WS P + C P + G T
Sbjct: 48 GEVFYYSCEYNFVSPSKSFWTRITCTEEG-WSPTPKCLRL--CFFPFVENGHSESSGQTH 104
Query: 547 TYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELT--SCPEPEVPSGGYM---EA 601
G Q C Y L E + + WS P C T SC P Y+ +
Sbjct: 105 LEGDTVQIICNTGYRLQNNENNISCVERGWSTP-PKCRSTDTSCVNPPTVQNAYIVSRQM 163
Query: 602 FDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYID--CGKLPTLPYGTMEL 659
Y + + C + +++ G+ ++C +G W+ + P C+ CG P + G +
Sbjct: 164 SKYPSGERVRYQCRSPYEMFGDEEVMCL-NGNWT-EPPQCKDSTGKCGPPPPIDNGDITS 221
Query: 660 LNGTTHL-GSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRC 701
+ + S ++Y C Y+L G R TC QWS+ P+C
Sbjct: 222 FPLSVYAPASSVEYQCQNLYQLEGNKRITC-RNGQWSE-PPKC 262
Score = 64.9 bits (151), Expect = 1e-09
Identities = 59/235 (25%), Positives = 98/235 (41%), Gaps = 25/235 (10%)
Query: 366 GNDYDVGSRIVYKCPEGHMLLGDKSR-HCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVAL 424
G + G + C G+ L +++ C + G WS PP C+ + + P + +
Sbjct: 101 GQTHLEGDTVQIICNTGYRLQNNENNISCVERG-WS-TPPKCRSTDTSCVNPPTVQNAYI 158
Query: 425 IDNRTTH---GARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDW--CPDPPAVSN 479
+ + + G R Y CR + + G+ E C + G W E P+C C PP + N
Sbjct: 159 VSRQMSKYPSGERVRYQCRSPYEMFGDEEVMCLN-GNWT-EPPQCKDSTGKCGPPPPIDN 216
Query: 480 ASVT---VNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTIHK 536
+T ++ + S Y C+N + L G+ +TC G WS PP C + + I +
Sbjct: 217 GDITSFPLSVYAPASSVEYQCQNLYQLEGNKRITCR-NGQWS-EPPKCLHPCVISREIME 274
Query: 537 GSFVLINGTTTY------GSIAQFTCEPDYWLNGAEELVCNR--DGKWSYDIPSC 583
+ + T G A+F C+ Y L+ + DGK Y P+C
Sbjct: 275 NYNIALRWTAKQKLYLRTGESAEFVCKRGYRLSSRSHTLRTTCWDGKLEY--PTC 327
Score = 61.3 bits (142), Expect = 2e-08
Identities = 67/226 (29%), Positives = 92/226 (40%), Gaps = 20/226 (8%)
Query: 746 GALVKYRCEKGYKVIGESL---STCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNA 802
G + Y CE + +S TC + G WS TP C + C P +ENG
Sbjct: 48 GEVFYYSCEYNFVSPSKSFWTRITCTEEG-WS-PTPKCLRL-CFFPF-VENGHSESSGQT 103
Query: 803 TFYGATAFYQCDENWELEGVIRRM-CQENGTWSLEPPICK--EITCPDPSAQIKAGSGLL 859
G T C+ + L+ + C E G WS PP C+ + +C +P ++ +
Sbjct: 104 HLEGDTVQIICNTGYRLQNNENNISCVERG-WST-PPKCRSTDTSCVNPPT-VQNAYIVS 160
Query: 860 VVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPID--CRSPGNIENGK 917
S G YQC Y + G + C++ G W P C C P I+NG
Sbjct: 161 RQMSKYPSGERVRYQCRSPYEMFGDEEVMCLN-GNWTEP-PQCKDSTGKCGPPPPIDNGD 218
Query: 918 IVISNGSTLF-GSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
I S SSVEY C + YQ G C +G+WS E P C
Sbjct: 219 ITSFPLSVYAPASSVEYQCQNLYQLEGNKRITC-RNGQWS-EPPKC 262
Score = 37.9 bits (84), Expect = 0.20
Identities = 20/57 (35%), Positives = 27/57 (47%), Gaps = 2/57 (3%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C +P NA + +G Y+C YE+FG + C L G+WT EPP C
Sbjct: 147 CVNPPTVQNAYIVSRQMSKYPSGERVRYQCRSPYEMFGDEEVMC-LNGNWT-EPPQC 201
>AY038048-1|AAK71497.1| 996|Homo sapiens SEZ6 protein.
Length = 996
Score = 79.8 bits (188), Expect = 5e-14
Identities = 92/382 (24%), Positives = 139/382 (36%), Gaps = 45/382 (11%)
Query: 479 NASVTVNGHKAGSLASYTCENGHILS-GSTSVTCT--LGGAWSGVPPSCKYVNCGTPTIH 535
N S + + G+ ++C+ G+ L GS + C W+ P+C+ V G T
Sbjct: 543 NFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAVCSGEITDS 602
Query: 536 KGSFVLINGTTTYGS----IAQFTCEPD--YWLNGAEELVCNRDGKWSYDIPSCELTSCP 589
G + N YG I E D L+ + D YD
Sbjct: 603 AGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPGDVLTFYDGDDLTARVLG 662
Query: 590 EPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKL 649
+ P + + F TI F + G ++G Q G C +L
Sbjct: 663 QYSGPRS-HFKLFTSMADVTIQFQSDPGTSVLG------YQQGFVIHFFEVPRNDTCPEL 715
Query: 650 PTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEI-RCSD 708
P +P G G+V+ Y C Y++VG C + WS+ P C+ + C D
Sbjct: 716 PEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVTSCHD 775
Query: 709 PIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCE 768
P D H LI + + +GA V+Y C++G+ ++G S+ TC
Sbjct: 776 P------------GDVEHSRRLISSP-------KFPVGATVQYICDQGFVLMGSSILTCH 816
Query: 769 D----NGQWSGTTPTC---QYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEG 821
D + +WS P C Q C ENG + GAT + C + L+G
Sbjct: 817 DRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKG 876
Query: 822 VIRRMCQEN--GTWSLEPPICK 841
C WS PPIC+
Sbjct: 877 QASIKCVPGHPSHWSDPPPICR 898
Score = 77.4 bits (182), Expect = 3e-13
Identities = 51/176 (28%), Positives = 78/176 (44%), Gaps = 13/176 (7%)
Query: 372 GSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYV-NCGGLTPIEDGDVALIDNRTT 430
G+ + Y+C G+ ++G C+ D WS PSC+ V +C +E + +
Sbjct: 733 GTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVTSCHDPGDVEHSRRLISSPKFP 792
Query: 431 HGARALYSCRENFTLVGNPERTCGDEGI----WDGEAPRCLFDW---CPDPPAVSNA--S 481
GA Y C + F L+G+ TC D W AP+CL + C A N S
Sbjct: 793 VGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENGARS 852
Query: 482 VTVNGHKAGSLASYTCENGHILSGSTSVTCTLG--GAWSGVPPSCKYVNC-GTPTI 534
H AG+ ++C G++L G S+ C G WS PP C+ + G+ T+
Sbjct: 853 PEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPICRAASLDGSTTV 908
Score = 76.6 bits (180), Expect = 5e-13
Identities = 48/165 (29%), Positives = 70/165 (42%), Gaps = 8/165 (4%)
Query: 746 GALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYV-DCGNPGRIENGKVTLPSNATF 804
G +V Y+C GY+V+G S+ C+ + WS P+CQ V C +PG +E+ + + S
Sbjct: 733 GTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVTSCHDPGDVEHSRRLISSPKFP 792
Query: 805 YGATAFYQCDENWELEGVIRRMCQE----NGTWSLEPPIC-KEITCPDPSAQIKAGSGLL 859
GAT Y CD+ + L G C + + WS P C E P
Sbjct: 793 VGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENGARS 852
Query: 860 VVTSTLSIGGEAHYQCERGYNLKGHQTRTCI--SKGQWNGTVPVC 902
G H+ C GY LKG + C+ W+ P+C
Sbjct: 853 PEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPIC 897
Score = 64.5 bits (150), Expect = 2e-09
Identities = 49/192 (25%), Positives = 73/192 (38%), Gaps = 12/192 (6%)
Query: 785 CGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEIT 844
C I NG + +G YQC +++ G MCQ + TWS + P C+ +T
Sbjct: 712 CPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVT 771
Query: 845 -CPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTC----ISKGQWNGTV 899
C DP S L+ + +G Y C++G+ L G TC +W+
Sbjct: 772 SCHDPGD--VEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRA 829
Query: 900 PVCIPID---CRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCL--DDGR 954
P C+ C ENG G+++ + C Y G KC+
Sbjct: 830 PKCLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSH 889
Query: 955 WSGEEPSCELAT 966
WS P C A+
Sbjct: 890 WSDPPPICRAAS 901
Score = 60.5 bits (140), Expect = 3e-08
Identities = 49/190 (25%), Positives = 71/190 (37%), Gaps = 13/190 (6%)
Query: 411 CGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRC-LFD 469
C L I +G + HG Y C + +VG+ C + W + P C
Sbjct: 712 CPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVT 771
Query: 470 WCPDPPAVSNASVTVNGHK--AGSLASYTCENGHILSGSTSVTC--TLGGA--WSGVPPS 523
C DP V ++ ++ K G+ Y C+ G +L GS+ +TC G+ WS P
Sbjct: 772 SCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPK 831
Query: 524 C---KYVNC-GTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVC--NRDGKWS 577
C + C G G+ G+ F+C P Y L G + C WS
Sbjct: 832 CLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWS 891
Query: 578 YDIPSCELTS 587
P C S
Sbjct: 892 DPPPICRAAS 901
Score = 44.4 bits (100), Expect = 0.002
Identities = 27/65 (41%), Positives = 36/65 (55%), Gaps = 8/65 (12%)
Query: 860 VVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQ--WNGTVPVCIPIDCRSPGNIEN-- 915
V ++L GG A + C GY LKG + TC++ Q W+ PVCI +C PG I N
Sbjct: 370 VTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIG-EC--PGVIRNAT 426
Query: 916 -GKIV 919
G+IV
Sbjct: 427 TGRIV 431
Score = 39.1 bits (87), Expect = 0.085
Identities = 29/107 (27%), Positives = 44/107 (41%), Gaps = 9/107 (8%)
Query: 369 YDVGSRIVYKCPEGHMLLGDK--SRHCKKDGF--WSGAPPSC---KYVNCGGLTPIEDGD 421
+ VG+ + Y C +G +L+G + H ++ G WS P C + C GL+ E+G
Sbjct: 791 FPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENGA 850
Query: 422 VALIDNRTTHGARALYSCRENFTLVGNPERTC--GDEGIWDGEAPRC 466
+ GA +SC + L G C G W P C
Sbjct: 851 RSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPIC 897
Score = 37.1 bits (82), Expect = 0.34
Identities = 21/61 (34%), Positives = 27/61 (44%)
Query: 907 CRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCELAT 966
C I NG S + G+ V Y C YQ VG + C D WS + PSC+ T
Sbjct: 712 CPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVT 771
Query: 967 N 967
+
Sbjct: 772 S 772
Score = 35.9 bits (79), Expect = 0.79
Identities = 19/71 (26%), Positives = 33/71 (46%), Gaps = 4/71 (5%)
Query: 650 PTLPYGTMELLNGTTHLGSVIQYSCTTNYRL-VGPVRRTCTE--EFQWSDSSPRCEEIRC 706
P + YG T +G+ +++SC Y L G + C + + QW+++ P C + C
Sbjct: 537 PFVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAV-C 595
Query: 707 SDPIVAEKSIV 717
S I +V
Sbjct: 596 SGEITDSAGVV 606
Score = 35.9 bits (79), Expect = 0.79
Identities = 18/56 (32%), Positives = 29/56 (51%), Gaps = 3/56 (5%)
Query: 5 PAVP--PNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
P +P PN S P++ +V GT+ Y+C GY++ G+ C W+ + P C
Sbjct: 713 PELPEIPNGWKS-PSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSC 767
Score = 34.7 bits (76), Expect = 1.8
Identities = 17/59 (28%), Positives = 25/59 (42%), Gaps = 2/59 (3%)
Query: 585 LTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGE--WSGDSPTC 641
L SC P P+ G + + + FHC G++L G +L C + W P C
Sbjct: 356 LLSCHFPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVC 414
Score = 33.1 bits (72), Expect = 5.6
Identities = 17/59 (28%), Positives = 27/59 (45%), Gaps = 3/59 (5%)
Query: 528 NCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAE---ELVCNRDGKWSYDIPSC 583
+C P + G+F T G+ +F+C+P Y L E V D +W+ P+C
Sbjct: 533 HCYEPFVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPAC 591
>AK223620-1|BAD97340.1| 994|Homo sapiens seizure related 6 homolog
protein.
Length = 994
Score = 79.8 bits (188), Expect = 5e-14
Identities = 92/382 (24%), Positives = 139/382 (36%), Gaps = 45/382 (11%)
Query: 479 NASVTVNGHKAGSLASYTCENGHILS-GSTSVTCT--LGGAWSGVPPSCKYVNCGTPTIH 535
N S + + G+ ++C+ G+ L GS + C W+ P+C+ V G T
Sbjct: 541 NFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAVCSGEITDS 600
Query: 536 KGSFVLINGTTTYGS----IAQFTCEPD--YWLNGAEELVCNRDGKWSYDIPSCELTSCP 589
G + N YG I E D L+ + D YD
Sbjct: 601 AGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPGDVLTFYDGDDLTARVLG 660
Query: 590 EPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKL 649
+ P + + F TI F + G ++G Q G C +L
Sbjct: 661 QYSGPRS-HFKLFTSMADVTIQFQSDPGTSVLG------YQQGFVIHFFEVPRNDTCPEL 713
Query: 650 PTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEI-RCSD 708
P +P G G+V+ Y C Y++VG C + WS+ P C+ + C D
Sbjct: 714 PEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVTSCHD 773
Query: 709 PIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCE 768
P D H LI + + +GA V+Y C++G+ ++G S+ TC
Sbjct: 774 P------------GDVEHSRRLISSP-------KFPVGATVQYICDQGFVLMGSSILTCH 814
Query: 769 D----NGQWSGTTPTC---QYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEG 821
D + +WS P C Q C ENG + GAT + C + L+G
Sbjct: 815 DRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKG 874
Query: 822 VIRRMCQEN--GTWSLEPPICK 841
C WS PPIC+
Sbjct: 875 QASIKCVPGHPSHWSDPPPICR 896
Score = 77.0 bits (181), Expect = 3e-13
Identities = 49/166 (29%), Positives = 73/166 (43%), Gaps = 12/166 (7%)
Query: 372 GSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYV-NCGGLTPIEDGDVALIDNRTT 430
G+ + Y+C G+ ++G C+ D WS PSC+ V +C +E + +
Sbjct: 731 GTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVTSCHDPGDVEHSRRLISSPKFP 790
Query: 431 HGARALYSCRENFTLVGNPERTCGDEGI----WDGEAPRCLFDW---CPDPPAVSNA--S 481
GA Y C + F L+G+ TC D W AP+CL + C A N S
Sbjct: 791 VGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENGARS 850
Query: 482 VTVNGHKAGSLASYTCENGHILSGSTSVTCTLG--GAWSGVPPSCK 525
H AG+ ++C G++L G S+ C G WS PP C+
Sbjct: 851 PEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPICR 896
Score = 76.6 bits (180), Expect = 5e-13
Identities = 48/165 (29%), Positives = 70/165 (42%), Gaps = 8/165 (4%)
Query: 746 GALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYV-DCGNPGRIENGKVTLPSNATF 804
G +V Y+C GY+V+G S+ C+ + WS P+CQ V C +PG +E+ + + S
Sbjct: 731 GTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVTSCHDPGDVEHSRRLISSPKFP 790
Query: 805 YGATAFYQCDENWELEGVIRRMCQE----NGTWSLEPPIC-KEITCPDPSAQIKAGSGLL 859
GAT Y CD+ + L G C + + WS P C E P
Sbjct: 791 VGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENGARS 850
Query: 860 VVTSTLSIGGEAHYQCERGYNLKGHQTRTCI--SKGQWNGTVPVC 902
G H+ C GY LKG + C+ W+ P+C
Sbjct: 851 PEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPIC 895
Score = 65.7 bits (153), Expect = 9e-10
Identities = 55/195 (28%), Positives = 85/195 (43%), Gaps = 17/195 (8%)
Query: 462 EAPRCLFDWCPDPPAVSNASVTVNGHKA--GSLASYTCENGHILSGSTSVTCTLGGAWSG 519
E PR D CP+ P + N + + + G++ +Y C G+ + GS+ + C WS
Sbjct: 703 EVPRN--DTCPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSE 760
Query: 520 VPPSCKYV-NCGTPTIHKGSFVLINGTT-TYGSIAQFTCEPDYWLNGAEELVCN----RD 573
PSC+ V +C P + S LI+ G+ Q+ C+ + L G+ L C+
Sbjct: 761 DLPSCQRVTSCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGS 820
Query: 574 GKWSYDIPSC---ELTSCPEPEVPSGGYM--EAFDYYVHSTINFHCEAGHKLIGEPNLVC 628
KWS P C +L C P G E + +TI+F C G+ L G+ ++ C
Sbjct: 821 PKWSDRAPKCLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKC 880
Query: 629 --QQDGEWSGDSPTC 641
WS P C
Sbjct: 881 VPGHPSHWSDPPPIC 895
Score = 64.5 bits (150), Expect = 2e-09
Identities = 49/192 (25%), Positives = 73/192 (38%), Gaps = 12/192 (6%)
Query: 785 CGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEIT 844
C I NG + +G YQC +++ G MCQ + TWS + P C+ +T
Sbjct: 710 CPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVT 769
Query: 845 -CPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTC----ISKGQWNGTV 899
C DP S L+ + +G Y C++G+ L G TC +W+
Sbjct: 770 SCHDPGD--VEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRA 827
Query: 900 PVCIPID---CRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCL--DDGR 954
P C+ C ENG G+++ + C Y G KC+
Sbjct: 828 PKCLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSH 887
Query: 955 WSGEEPSCELAT 966
WS P C A+
Sbjct: 888 WSDPPPICRAAS 899
Score = 60.5 bits (140), Expect = 3e-08
Identities = 49/190 (25%), Positives = 71/190 (37%), Gaps = 13/190 (6%)
Query: 411 CGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRC-LFD 469
C L I +G + HG Y C + +VG+ C + W + P C
Sbjct: 710 CPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVT 769
Query: 470 WCPDPPAVSNASVTVNGHK--AGSLASYTCENGHILSGSTSVTC--TLGGA--WSGVPPS 523
C DP V ++ ++ K G+ Y C+ G +L GS+ +TC G+ WS P
Sbjct: 770 SCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPK 829
Query: 524 C---KYVNC-GTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVC--NRDGKWS 577
C + C G G+ G+ F+C P Y L G + C WS
Sbjct: 830 CLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWS 889
Query: 578 YDIPSCELTS 587
P C S
Sbjct: 890 DPPPICRAAS 899
Score = 43.2 bits (97), Expect = 0.005
Identities = 23/62 (37%), Positives = 31/62 (50%), Gaps = 2/62 (3%)
Query: 860 VVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQ--WNGTVPVCIPIDCRSPGNIENGK 917
V ++L GG A + C GY LKG + TC++ Q W+ PVCI N G+
Sbjct: 368 VTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIAACGGVIRNATTGR 427
Query: 918 IV 919
IV
Sbjct: 428 IV 429
Score = 39.1 bits (87), Expect = 0.085
Identities = 29/107 (27%), Positives = 44/107 (41%), Gaps = 9/107 (8%)
Query: 369 YDVGSRIVYKCPEGHMLLGDK--SRHCKKDGF--WSGAPPSC---KYVNCGGLTPIEDGD 421
+ VG+ + Y C +G +L+G + H ++ G WS P C + C GL+ E+G
Sbjct: 789 FPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENGA 848
Query: 422 VALIDNRTTHGARALYSCRENFTLVGNPERTC--GDEGIWDGEAPRC 466
+ GA +SC + L G C G W P C
Sbjct: 849 RSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPIC 895
Score = 37.1 bits (82), Expect = 0.34
Identities = 65/267 (24%), Positives = 100/267 (37%), Gaps = 43/267 (16%)
Query: 472 PDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGA--WSGVPPSCKYVNC 529
P PA + +VT + H GS A + C G+ L G+ +TC W P C C
Sbjct: 360 PRRPAYGDVTVT-SLHPGGS-ARFHCATGYQLKGARHLTCLNATQPFWDSKEPVC-IAAC 416
Query: 530 GTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPS------- 582
G V+ N TT G I P + N + L C+ W + P
Sbjct: 417 GG--------VIRNATT--GRIVS----PGFPGNYSNNLTCH----WLLEAPEGQRLHLH 458
Query: 583 CELTSCPEPE----VPSGGYMEAFDYYVHSTINFHCEAGHKLIGEP---NLVCQQDGEWS 635
E S E + + +G +EA Y + + G G+ L G +
Sbjct: 459 FEKVSLAEDDDRLIIRNGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAA 518
Query: 636 GDSPTCEYIDCGKL--PTLPYGTMELLNGTTHLGSVIQYSCTTNYRL-VGPVRRTCTE-- 690
G + E G P + YG T +G+ +++SC Y L G + C +
Sbjct: 519 GMALRYEAFQQGHCYEPFVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPH 578
Query: 691 EFQWSDSSPRCEEIRCSDPIVAEKSIV 717
+ QW+++ P C + CS I +V
Sbjct: 579 DPQWNETEPACRAV-CSGEITDSAGVV 604
Score = 37.1 bits (82), Expect = 0.34
Identities = 21/61 (34%), Positives = 27/61 (44%)
Query: 907 CRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCELAT 966
C I NG S + G+ V Y C YQ VG + C D WS + PSC+ T
Sbjct: 710 CPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVT 769
Query: 967 N 967
+
Sbjct: 770 S 770
Score = 35.9 bits (79), Expect = 0.79
Identities = 18/56 (32%), Positives = 29/56 (51%), Gaps = 3/56 (5%)
Query: 5 PAVP--PNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
P +P PN S P++ +V GT+ Y+C GY++ G+ C W+ + P C
Sbjct: 711 PELPEIPNGWKS-PSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSC 765
Score = 34.7 bits (76), Expect = 1.8
Identities = 17/59 (28%), Positives = 25/59 (42%), Gaps = 2/59 (3%)
Query: 585 LTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGE--WSGDSPTC 641
L SC P P+ G + + + FHC G++L G +L C + W P C
Sbjct: 354 LLSCHLPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVC 412
>AK091522-1|BAC03684.1| 869|Homo sapiens protein ( Homo sapiens
cDNA FLJ34203 fis, clone FCBBF3019784, highly similar to
Mouse mRNA for seizure-related gene product 6 type 2
precursor. ).
Length = 869
Score = 79.8 bits (188), Expect = 5e-14
Identities = 92/382 (24%), Positives = 139/382 (36%), Gaps = 45/382 (11%)
Query: 479 NASVTVNGHKAGSLASYTCENGHILS-GSTSVTCT--LGGAWSGVPPSCKYVNCGTPTIH 535
N S + + G+ ++C+ G+ L GS + C W+ P+C+ V G T
Sbjct: 416 NFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAVCSGEITDS 475
Query: 536 KGSFVLINGTTTYGS----IAQFTCEPD--YWLNGAEELVCNRDGKWSYDIPSCELTSCP 589
G + N YG I E D L+ + D YD
Sbjct: 476 AGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPGDVLTFYDGDDLTARVLG 535
Query: 590 EPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKL 649
+ P + + F TI F + G ++G Q G C +L
Sbjct: 536 QYSGPRS-HFKLFTSMADVTIQFQSDPGTSVLG------YQQGFVIHFFEVPRNDTCPEL 588
Query: 650 PTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEI-RCSD 708
P +P G G+V+ Y C Y++VG C + WS+ P C+ + C D
Sbjct: 589 PEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVTSCHD 648
Query: 709 PIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCE 768
P D H LI + + +GA V+Y C++G+ ++G S+ TC
Sbjct: 649 P------------GDVEHSRRLISSP-------KFPVGATVQYICDQGFVLMGSSILTCH 689
Query: 769 D----NGQWSGTTPTC---QYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEG 821
D + +WS P C Q C ENG + GAT + C + L+G
Sbjct: 690 DRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKG 749
Query: 822 VIRRMCQEN--GTWSLEPPICK 841
C WS PPIC+
Sbjct: 750 QASIKCVPGHPSHWSDPPPICR 771
Score = 77.0 bits (181), Expect = 3e-13
Identities = 49/166 (29%), Positives = 73/166 (43%), Gaps = 12/166 (7%)
Query: 372 GSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYV-NCGGLTPIEDGDVALIDNRTT 430
G+ + Y+C G+ ++G C+ D WS PSC+ V +C +E + +
Sbjct: 606 GTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVTSCHDPGDVEHSRRLISSPKFP 665
Query: 431 HGARALYSCRENFTLVGNPERTCGDEGI----WDGEAPRCLFDW---CPDPPAVSNA--S 481
GA Y C + F L+G+ TC D W AP+CL + C A N S
Sbjct: 666 VGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENGARS 725
Query: 482 VTVNGHKAGSLASYTCENGHILSGSTSVTCTLG--GAWSGVPPSCK 525
H AG+ ++C G++L G S+ C G WS PP C+
Sbjct: 726 PEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPICR 771
Score = 76.6 bits (180), Expect = 5e-13
Identities = 48/165 (29%), Positives = 70/165 (42%), Gaps = 8/165 (4%)
Query: 746 GALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYV-DCGNPGRIENGKVTLPSNATF 804
G +V Y+C GY+V+G S+ C+ + WS P+CQ V C +PG +E+ + + S
Sbjct: 606 GTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVTSCHDPGDVEHSRRLISSPKFP 665
Query: 805 YGATAFYQCDENWELEGVIRRMCQE----NGTWSLEPPIC-KEITCPDPSAQIKAGSGLL 859
GAT Y CD+ + L G C + + WS P C E P
Sbjct: 666 VGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENGARS 725
Query: 860 VVTSTLSIGGEAHYQCERGYNLKGHQTRTCI--SKGQWNGTVPVC 902
G H+ C GY LKG + C+ W+ P+C
Sbjct: 726 PEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPIC 770
Score = 65.7 bits (153), Expect = 9e-10
Identities = 55/195 (28%), Positives = 85/195 (43%), Gaps = 17/195 (8%)
Query: 462 EAPRCLFDWCPDPPAVSNASVTVNGHKA--GSLASYTCENGHILSGSTSVTCTLGGAWSG 519
E PR D CP+ P + N + + + G++ +Y C G+ + GS+ + C WS
Sbjct: 578 EVPRN--DTCPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSE 635
Query: 520 VPPSCKYV-NCGTPTIHKGSFVLINGTT-TYGSIAQFTCEPDYWLNGAEELVCN----RD 573
PSC+ V +C P + S LI+ G+ Q+ C+ + L G+ L C+
Sbjct: 636 DLPSCQRVTSCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGS 695
Query: 574 GKWSYDIPSC---ELTSCPEPEVPSGGYM--EAFDYYVHSTINFHCEAGHKLIGEPNLVC 628
KWS P C +L C P G E + +TI+F C G+ L G+ ++ C
Sbjct: 696 PKWSDRAPKCLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKC 755
Query: 629 --QQDGEWSGDSPTC 641
WS P C
Sbjct: 756 VPGHPSHWSDPPPIC 770
Score = 64.5 bits (150), Expect = 2e-09
Identities = 49/192 (25%), Positives = 73/192 (38%), Gaps = 12/192 (6%)
Query: 785 CGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEIT 844
C I NG + +G YQC +++ G MCQ + TWS + P C+ +T
Sbjct: 585 CPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVT 644
Query: 845 -CPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTC----ISKGQWNGTV 899
C DP S L+ + +G Y C++G+ L G TC +W+
Sbjct: 645 SCHDPGD--VEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRA 702
Query: 900 PVCIPID---CRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCL--DDGR 954
P C+ C ENG G+++ + C Y G KC+
Sbjct: 703 PKCLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSH 762
Query: 955 WSGEEPSCELAT 966
WS P C A+
Sbjct: 763 WSDPPPICRAAS 774
Score = 60.5 bits (140), Expect = 3e-08
Identities = 49/190 (25%), Positives = 71/190 (37%), Gaps = 13/190 (6%)
Query: 411 CGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRC-LFD 469
C L I +G + HG Y C + +VG+ C + W + P C
Sbjct: 585 CPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVT 644
Query: 470 WCPDPPAVSNASVTVNGHK--AGSLASYTCENGHILSGSTSVTC--TLGGA--WSGVPPS 523
C DP V ++ ++ K G+ Y C+ G +L GS+ +TC G+ WS P
Sbjct: 645 SCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPK 704
Query: 524 C---KYVNC-GTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVC--NRDGKWS 577
C + C G G+ G+ F+C P Y L G + C WS
Sbjct: 705 CLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWS 764
Query: 578 YDIPSCELTS 587
P C S
Sbjct: 765 DPPPICRAAS 774
Score = 43.2 bits (97), Expect = 0.005
Identities = 23/62 (37%), Positives = 31/62 (50%), Gaps = 2/62 (3%)
Query: 860 VVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQ--WNGTVPVCIPIDCRSPGNIENGK 917
V ++L GG A + C GY LKG + TC++ Q W+ PVCI N G+
Sbjct: 243 VTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIAACGGVIRNATTGR 302
Query: 918 IV 919
IV
Sbjct: 303 IV 304
Score = 39.1 bits (87), Expect = 0.085
Identities = 29/107 (27%), Positives = 44/107 (41%), Gaps = 9/107 (8%)
Query: 369 YDVGSRIVYKCPEGHMLLGDK--SRHCKKDGF--WSGAPPSC---KYVNCGGLTPIEDGD 421
+ VG+ + Y C +G +L+G + H ++ G WS P C + C GL+ E+G
Sbjct: 664 FPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENGA 723
Query: 422 VALIDNRTTHGARALYSCRENFTLVGNPERTC--GDEGIWDGEAPRC 466
+ GA +SC + L G C G W P C
Sbjct: 724 RSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPIC 770
Score = 37.5 bits (83), Expect = 0.26
Identities = 63/268 (23%), Positives = 96/268 (35%), Gaps = 41/268 (15%)
Query: 471 CPDPPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGA--WSGVPPSCKYVN 528
C P + VTV G A + C G+ L G+ +TC W P C
Sbjct: 232 CHFPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVC-IAA 290
Query: 529 CGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPS------ 582
CG V+ N TT G I P + N + L C+ W + P
Sbjct: 291 CGG--------VIRNATT--GRIVS----PGFPGNYSNNLTCH----WLLEAPEGQRLHL 332
Query: 583 -CELTSCPEPE----VPSGGYMEAFDYYVHSTINFHCEAGHKLIGEP---NLVCQQDGEW 634
E S E + + +G +EA Y + + G G+ L G
Sbjct: 333 HFEKVSLAEDDDRLIIRNGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAA 392
Query: 635 SGDSPTCEYIDCGKL--PTLPYGTMELLNGTTHLGSVIQYSCTTNYRL-VGPVRRTCTE- 690
+G + E G P + YG T +G+ +++SC Y L G + C +
Sbjct: 393 AGMALRYEAFQQGHCYEPFVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDP 452
Query: 691 -EFQWSDSSPRCEEIRCSDPIVAEKSIV 717
+ QW+++ P C + CS I +V
Sbjct: 453 HDPQWNETEPACRAV-CSGEITDSAGVV 479
Score = 37.1 bits (82), Expect = 0.34
Identities = 21/61 (34%), Positives = 27/61 (44%)
Query: 907 CRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCELAT 966
C I NG S + G+ V Y C YQ VG + C D WS + PSC+ T
Sbjct: 585 CPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVT 644
Query: 967 N 967
+
Sbjct: 645 S 645
Score = 35.9 bits (79), Expect = 0.79
Identities = 18/56 (32%), Positives = 29/56 (51%), Gaps = 3/56 (5%)
Query: 5 PAVP--PNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
P +P PN S P++ +V GT+ Y+C GY++ G+ C W+ + P C
Sbjct: 586 PELPEIPNGWKS-PSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSC 640
Score = 34.7 bits (76), Expect = 1.8
Identities = 17/59 (28%), Positives = 25/59 (42%), Gaps = 2/59 (3%)
Query: 585 LTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGE--WSGDSPTC 641
L SC P P+ G + + + FHC G++L G +L C + W P C
Sbjct: 229 LLSCHFPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVC 287
>AF502129-1|AAM22213.1| 996|Homo sapiens HSEZ6b protein protein.
Length = 996
Score = 79.8 bits (188), Expect = 5e-14
Identities = 92/382 (24%), Positives = 139/382 (36%), Gaps = 45/382 (11%)
Query: 479 NASVTVNGHKAGSLASYTCENGHILS-GSTSVTCT--LGGAWSGVPPSCKYVNCGTPTIH 535
N S + + G+ ++C+ G+ L GS + C W+ P+C+ V G T
Sbjct: 543 NFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAVCSGEITDS 602
Query: 536 KGSFVLINGTTTYGS----IAQFTCEPD--YWLNGAEELVCNRDGKWSYDIPSCELTSCP 589
G + N YG I E D L+ + D YD
Sbjct: 603 AGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPGDVLTFYDGDDLTARVLG 662
Query: 590 EPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKL 649
+ P + + F TI F + G ++G Q G C +L
Sbjct: 663 QYSGPRS-HFKLFTSMADVTIQFQSDPGTSVLG------YQQGFVIHFFEVPRNDTCPEL 715
Query: 650 PTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEI-RCSD 708
P +P G G+V+ Y C Y++VG C + WS+ P C+ + C D
Sbjct: 716 PEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVTSCHD 775
Query: 709 PIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCE 768
P D H LI + + +GA V+Y C++G+ ++G S+ TC
Sbjct: 776 P------------GDVEHSRRLISSP-------KFPVGATVQYICDQGFVLMGSSILTCH 816
Query: 769 D----NGQWSGTTPTC---QYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEG 821
D + +WS P C Q C ENG + GAT + C + L+G
Sbjct: 817 DRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKG 876
Query: 822 VIRRMCQEN--GTWSLEPPICK 841
C WS PPIC+
Sbjct: 877 QASIKCVPGHPSHWSDPPPICR 898
Score = 77.4 bits (182), Expect = 3e-13
Identities = 51/176 (28%), Positives = 78/176 (44%), Gaps = 13/176 (7%)
Query: 372 GSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYV-NCGGLTPIEDGDVALIDNRTT 430
G+ + Y+C G+ ++G C+ D WS PSC+ V +C +E + +
Sbjct: 733 GTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVTSCHDPGDVEHSRRLISSPKFP 792
Query: 431 HGARALYSCRENFTLVGNPERTCGDEGI----WDGEAPRCLFDW---CPDPPAVSNA--S 481
GA Y C + F L+G+ TC D W AP+CL + C A N S
Sbjct: 793 VGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENGARS 852
Query: 482 VTVNGHKAGSLASYTCENGHILSGSTSVTCTLG--GAWSGVPPSCKYVNC-GTPTI 534
H AG+ ++C G++L G S+ C G WS PP C+ + G+ T+
Sbjct: 853 PEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPICRAASLDGSTTV 908
Score = 76.6 bits (180), Expect = 5e-13
Identities = 48/165 (29%), Positives = 70/165 (42%), Gaps = 8/165 (4%)
Query: 746 GALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYV-DCGNPGRIENGKVTLPSNATF 804
G +V Y+C GY+V+G S+ C+ + WS P+CQ V C +PG +E+ + + S
Sbjct: 733 GTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVTSCHDPGDVEHSRRLISSPKFP 792
Query: 805 YGATAFYQCDENWELEGVIRRMCQE----NGTWSLEPPIC-KEITCPDPSAQIKAGSGLL 859
GAT Y CD+ + L G C + + WS P C E P
Sbjct: 793 VGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENGARS 852
Query: 860 VVTSTLSIGGEAHYQCERGYNLKGHQTRTCI--SKGQWNGTVPVC 902
G H+ C GY LKG + C+ W+ P+C
Sbjct: 853 PEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPIC 897
Score = 64.5 bits (150), Expect = 2e-09
Identities = 49/192 (25%), Positives = 73/192 (38%), Gaps = 12/192 (6%)
Query: 785 CGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEIT 844
C I NG + +G YQC +++ G MCQ + TWS + P C+ +T
Sbjct: 712 CPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVT 771
Query: 845 -CPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTC----ISKGQWNGTV 899
C DP S L+ + +G Y C++G+ L G TC +W+
Sbjct: 772 SCHDPGD--VEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRA 829
Query: 900 PVCIPID---CRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCL--DDGR 954
P C+ C ENG G+++ + C Y G KC+
Sbjct: 830 PKCLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSH 889
Query: 955 WSGEEPSCELAT 966
WS P C A+
Sbjct: 890 WSDPPPICRAAS 901
Score = 60.5 bits (140), Expect = 3e-08
Identities = 49/190 (25%), Positives = 71/190 (37%), Gaps = 13/190 (6%)
Query: 411 CGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRC-LFD 469
C L I +G + HG Y C + +VG+ C + W + P C
Sbjct: 712 CPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVT 771
Query: 470 WCPDPPAVSNASVTVNGHK--AGSLASYTCENGHILSGSTSVTC--TLGGA--WSGVPPS 523
C DP V ++ ++ K G+ Y C+ G +L GS+ +TC G+ WS P
Sbjct: 772 SCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPK 831
Query: 524 C---KYVNC-GTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVC--NRDGKWS 577
C + C G G+ G+ F+C P Y L G + C WS
Sbjct: 832 CLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWS 891
Query: 578 YDIPSCELTS 587
P C S
Sbjct: 892 DPPPICRAAS 901
Score = 44.4 bits (100), Expect = 0.002
Identities = 27/65 (41%), Positives = 36/65 (55%), Gaps = 8/65 (12%)
Query: 860 VVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQ--WNGTVPVCIPIDCRSPGNIEN-- 915
V ++L GG A + C GY LKG + TC++ Q W+ PVCI +C PG I N
Sbjct: 370 VTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIG-EC--PGVIRNAT 426
Query: 916 -GKIV 919
G+IV
Sbjct: 427 TGRIV 431
Score = 39.1 bits (87), Expect = 0.085
Identities = 29/107 (27%), Positives = 44/107 (41%), Gaps = 9/107 (8%)
Query: 369 YDVGSRIVYKCPEGHMLLGDK--SRHCKKDGF--WSGAPPSC---KYVNCGGLTPIEDGD 421
+ VG+ + Y C +G +L+G + H ++ G WS P C + C GL+ E+G
Sbjct: 791 FPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENGA 850
Query: 422 VALIDNRTTHGARALYSCRENFTLVGNPERTC--GDEGIWDGEAPRC 466
+ GA +SC + L G C G W P C
Sbjct: 851 RSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPIC 897
Score = 37.1 bits (82), Expect = 0.34
Identities = 21/61 (34%), Positives = 27/61 (44%)
Query: 907 CRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCELAT 966
C I NG S + G+ V Y C YQ VG + C D WS + PSC+ T
Sbjct: 712 CPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVT 771
Query: 967 N 967
+
Sbjct: 772 S 772
Score = 35.9 bits (79), Expect = 0.79
Identities = 19/71 (26%), Positives = 33/71 (46%), Gaps = 4/71 (5%)
Query: 650 PTLPYGTMELLNGTTHLGSVIQYSCTTNYRL-VGPVRRTCTE--EFQWSDSSPRCEEIRC 706
P + YG T +G+ +++SC Y L G + C + + QW+++ P C + C
Sbjct: 537 PFVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAV-C 595
Query: 707 SDPIVAEKSIV 717
S I +V
Sbjct: 596 SGEITDSAGVV 606
Score = 35.9 bits (79), Expect = 0.79
Identities = 18/56 (32%), Positives = 29/56 (51%), Gaps = 3/56 (5%)
Query: 5 PAVP--PNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
P +P PN S P++ +V GT+ Y+C GY++ G+ C W+ + P C
Sbjct: 713 PELPEIPNGWKS-PSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSC 767
Score = 34.7 bits (76), Expect = 1.8
Identities = 17/59 (28%), Positives = 25/59 (42%), Gaps = 2/59 (3%)
Query: 585 LTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGE--WSGDSPTC 641
L SC P P+ G + + + FHC G++L G +L C + W P C
Sbjct: 356 LLSCHFPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVC 414
Score = 33.1 bits (72), Expect = 5.6
Identities = 17/59 (28%), Positives = 27/59 (45%), Gaps = 3/59 (5%)
Query: 528 NCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAE---ELVCNRDGKWSYDIPSC 583
+C P + G+F T G+ +F+C+P Y L E V D +W+ P+C
Sbjct: 533 HCYEPFVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPAC 591
>M65293-1|AAA35947.1| 330|Homo sapiens factor H homologue protein.
Length = 330
Score = 79.0 bits (186), Expect = 9e-14
Identities = 86/290 (29%), Positives = 122/290 (42%), Gaps = 45/290 (15%)
Query: 626 LVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHL-GSVIQYSCTTNYRLVGPV 684
+ C ++G WS PT + + P + G E +G THL G +Q C T YRL
Sbjct: 70 ITCTEEG-WS---PTPKCLRLCFFPFVENGHSES-SGQTHLEGDTVQIICNTGYRLQNNE 124
Query: 685 RRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYR 744
E WS + P+C R +D V + H L R + Y
Sbjct: 125 NNISCVERGWS-TPPKC---RSTDTSCVNPPTV-------QNAHILSRQM------SKYP 167
Query: 745 IGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQ--YVDCGNPGRIENGKVT-LPSN 801
G V+Y C Y++ G+ C NG W+ P C+ CG P I+NG +T P +
Sbjct: 168 SGERVRYECRSPYEMFGDEEVMCL-NGNWT-EPPQCKDSTGKCGPPPPIDNGDITSFPLS 225
Query: 802 ATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVV 861
++ YQC ++LEG R C+ NG WS EPP C C S +I + +
Sbjct: 226 VYAPASSVEYQCQNLYQLEGNKRITCR-NGQWS-EPPKCLH-PCV-ISREIMENYNIALR 281
Query: 862 TST-----LSIGGEAHYQCERGYNL--KGHQTRTCISKGQWNGTV--PVC 902
+ L G A + C+RGY L + H RT W+G + P C
Sbjct: 282 WTAKQKLYLRTGESAEFVCKRGYRLSSRSHTLRTTC----WDGKLEYPTC 327
Score = 64.5 bits (150), Expect = 2e-09
Identities = 59/235 (25%), Positives = 98/235 (41%), Gaps = 25/235 (10%)
Query: 366 GNDYDVGSRIVYKCPEGHMLLGDKSR-HCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVAL 424
G + G + C G+ L +++ C + G WS PP C+ + + P + +
Sbjct: 101 GQTHLEGDTVQIICNTGYRLQNNENNISCVERG-WS-TPPKCRSTDTSCVNPPTVQNAHI 158
Query: 425 IDNRTTH---GARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDW--CPDPPAVSN 479
+ + + G R Y CR + + G+ E C + G W E P+C C PP + N
Sbjct: 159 LSRQMSKYPSGERVRYECRSPYEMFGDEEVMCLN-GNWT-EPPQCKDSTGKCGPPPPIDN 216
Query: 480 ASVT---VNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTIHK 536
+T ++ + S Y C+N + L G+ +TC G WS PP C + + I +
Sbjct: 217 GDITSFPLSVYAPASSVEYQCQNLYQLEGNKRITCR-NGQWS-EPPKCLHPCVISREIME 274
Query: 537 GSFVLINGTTTY------GSIAQFTCEPDYWLNGAEELVCNR--DGKWSYDIPSC 583
+ + T G A+F C+ Y L+ + DGK Y P+C
Sbjct: 275 NYNIALRWTAKQKLYLRTGESAEFVCKRGYRLSSRSHTLRTTCWDGKLEY--PTC 327
Score = 61.7 bits (143), Expect = 1e-08
Identities = 67/226 (29%), Positives = 92/226 (40%), Gaps = 20/226 (8%)
Query: 746 GALVKYRCEKGYKVIGESL---STCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNA 802
G + Y CE + +S TC + G WS TP C + C P +ENG
Sbjct: 48 GEVFYYSCEYNFVSPSKSFWTRITCTEEG-WS-PTPKCLRL-CFFPF-VENGHSESSGQT 103
Query: 803 TFYGATAFYQCDENWELEGVIRRM-CQENGTWSLEPPICK--EITCPDPSAQIKAGSGLL 859
G T C+ + L+ + C E G WS PP C+ + +C +P ++ L
Sbjct: 104 HLEGDTVQIICNTGYRLQNNENNISCVERG-WST-PPKCRSTDTSCVNPPT-VQNAHILS 160
Query: 860 VVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPID--CRSPGNIENGK 917
S G Y+C Y + G + C++ G W P C C P I+NG
Sbjct: 161 RQMSKYPSGERVRYECRSPYEMFGDEEVMCLN-GNWTEP-PQCKDSTGKCGPPPPIDNGD 218
Query: 918 IVISNGSTLF-GSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
I S SSVEY C + YQ G C +G+WS E P C
Sbjct: 219 ITSFPLSVYAPASSVEYQCQNLYQLEGNKRITC-RNGQWS-EPPKC 262
Score = 39.9 bits (89), Expect = 0.049
Identities = 21/57 (36%), Positives = 27/57 (47%), Gaps = 2/57 (3%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C +P NA + +G YEC YE+FG + C L G+WT EPP C
Sbjct: 147 CVNPPTVQNAHILSRQMSKYPSGERVRYECRSPYEMFGDEEVMC-LNGNWT-EPPQC 201
>BC107771-1|AAI07772.1| 330|Homo sapiens complement factor
H-related 1 protein.
Length = 330
Score = 79.0 bits (186), Expect = 9e-14
Identities = 86/290 (29%), Positives = 122/290 (42%), Gaps = 45/290 (15%)
Query: 626 LVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHL-GSVIQYSCTTNYRLVGPV 684
+ C ++G WS PT + + P + G E +G THL G +Q C T YRL
Sbjct: 70 ITCTEEG-WS---PTPKCLRLCFFPFVENGHSES-SGQTHLEGDTVQIICNTGYRLQNNE 124
Query: 685 RRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYR 744
E WS + P+C R +D V + H L R + Y
Sbjct: 125 NNISCVERGWS-TPPKC---RSTDTSCVNPPTV-------QNAHILSRQM------SKYP 167
Query: 745 IGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQ--YVDCGNPGRIENGKVT-LPSN 801
G V+Y C Y++ G+ C NG W+ P C+ CG P I+NG +T P +
Sbjct: 168 SGERVRYECRSPYEMFGDEEVMCL-NGNWT-EPPQCKDSTGKCGPPPPIDNGDITSFPLS 225
Query: 802 ATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVV 861
++ YQC ++LEG R C+ NG WS EPP C C S +I + +
Sbjct: 226 VYAPASSVEYQCQNLYQLEGNKRITCR-NGQWS-EPPKCLH-PCV-ISREIMENYNIALR 281
Query: 862 TST-----LSIGGEAHYQCERGYNL--KGHQTRTCISKGQWNGTV--PVC 902
+ L G A + C+RGY L + H RT W+G + P C
Sbjct: 282 WTAKQKLYLRTGESAEFVCKRGYRLSSRSHTLRTTC----WDGKLEYPTC 327
Score = 64.5 bits (150), Expect = 2e-09
Identities = 59/235 (25%), Positives = 98/235 (41%), Gaps = 25/235 (10%)
Query: 366 GNDYDVGSRIVYKCPEGHMLLGDKSR-HCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVAL 424
G + G + C G+ L +++ C + G WS PP C+ + + P + +
Sbjct: 101 GQTHLEGDTVQIICNTGYRLQNNENNISCVERG-WS-TPPKCRSTDTSCVNPPTVQNAHI 158
Query: 425 IDNRTTH---GARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDW--CPDPPAVSN 479
+ + + G R Y CR + + G+ E C + G W E P+C C PP + N
Sbjct: 159 LSRQMSKYPSGERVRYECRSPYEMFGDEEVMCLN-GNWT-EPPQCKDSTGKCGPPPPIDN 216
Query: 480 ASVT---VNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTIHK 536
+T ++ + S Y C+N + L G+ +TC G WS PP C + + I +
Sbjct: 217 GDITSFPLSVYAPASSVEYQCQNLYQLEGNKRITCR-NGQWS-EPPKCLHPCVISREIME 274
Query: 537 GSFVLINGTTTY------GSIAQFTCEPDYWLNGAEELVCNR--DGKWSYDIPSC 583
+ + T G A+F C+ Y L+ + DGK Y P+C
Sbjct: 275 NYNIALRWTAKQKLYLRTGESAEFVCKRGYRLSSRSHTLRTTCWDGKLEY--PTC 327
Score = 61.7 bits (143), Expect = 1e-08
Identities = 67/226 (29%), Positives = 92/226 (40%), Gaps = 20/226 (8%)
Query: 746 GALVKYRCEKGYKVIGESL---STCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNA 802
G + Y CE + +S TC + G WS TP C + C P +ENG
Sbjct: 48 GEVFYYSCEYNFVSPSKSFWTRITCTEEG-WS-PTPKCLRL-CFFPF-VENGHSESSGQT 103
Query: 803 TFYGATAFYQCDENWELEGVIRRM-CQENGTWSLEPPICK--EITCPDPSAQIKAGSGLL 859
G T C+ + L+ + C E G WS PP C+ + +C +P ++ L
Sbjct: 104 HLEGDTVQIICNTGYRLQNNENNISCVERG-WST-PPKCRSTDTSCVNPPT-VQNAHILS 160
Query: 860 VVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPID--CRSPGNIENGK 917
S G Y+C Y + G + C++ G W P C C P I+NG
Sbjct: 161 RQMSKYPSGERVRYECRSPYEMFGDEEVMCLN-GNWTEP-PQCKDSTGKCGPPPPIDNGD 218
Query: 918 IVISNGSTLF-GSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
I S SSVEY C + YQ G C +G+WS E P C
Sbjct: 219 ITSFPLSVYAPASSVEYQCQNLYQLEGNKRITC-RNGQWS-EPPKC 262
Score = 39.9 bits (89), Expect = 0.049
Identities = 21/57 (36%), Positives = 27/57 (47%), Gaps = 2/57 (3%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C +P NA + +G YEC YE+FG + C L G+WT EPP C
Sbjct: 147 CVNPPTVQNAHILSRQMSKYPSGERVRYECRSPYEMFGDEEVMC-LNGNWT-EPPQC 201
>BC016755-1|AAH16755.1| 330|Homo sapiens complement factor
H-related 1 protein.
Length = 330
Score = 79.0 bits (186), Expect = 9e-14
Identities = 86/290 (29%), Positives = 122/290 (42%), Gaps = 45/290 (15%)
Query: 626 LVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHL-GSVIQYSCTTNYRLVGPV 684
+ C ++G WS PT + + P + G E +G THL G +Q C T YRL
Sbjct: 70 ITCTEEG-WS---PTPKCLRLCFFPFVENGHSES-SGQTHLEGDTVQIICNTGYRLQNNE 124
Query: 685 RRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYR 744
E WS + P+C R +D V + H L R + Y
Sbjct: 125 NNISCVERGWS-TPPKC---RSTDTSCVNPPTV-------QNAHILSRQM------SKYP 167
Query: 745 IGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQ--YVDCGNPGRIENGKVT-LPSN 801
G V+Y C Y++ G+ C NG W+ P C+ CG P I+NG +T P +
Sbjct: 168 SGERVRYECRSPYEMFGDEEVMCL-NGNWT-EPPQCKDSTGKCGPPPPIDNGDITSFPLS 225
Query: 802 ATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVV 861
++ YQC ++LEG R C+ NG WS EPP C C S +I + +
Sbjct: 226 VYAPASSVEYQCQNLYQLEGNKRITCR-NGQWS-EPPKCLH-PCV-ISREIMENYNIALR 281
Query: 862 TST-----LSIGGEAHYQCERGYNL--KGHQTRTCISKGQWNGTV--PVC 902
+ L G A + C+RGY L + H RT W+G + P C
Sbjct: 282 WTAKQKLYLRTGESAEFVCKRGYRLSSRSHTLRTTC----WDGKLEYPTC 327
Score = 64.5 bits (150), Expect = 2e-09
Identities = 59/235 (25%), Positives = 98/235 (41%), Gaps = 25/235 (10%)
Query: 366 GNDYDVGSRIVYKCPEGHMLLGDKSR-HCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVAL 424
G + G + C G+ L +++ C + G WS PP C+ + + P + +
Sbjct: 101 GQTHLEGDTVQIICNTGYRLQNNENNISCVERG-WS-TPPKCRSTDTSCVNPPTVQNAHI 158
Query: 425 IDNRTTH---GARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDW--CPDPPAVSN 479
+ + + G R Y CR + + G+ E C + G W E P+C C PP + N
Sbjct: 159 LSRQMSKYPSGERVRYECRSPYEMFGDEEVMCLN-GNWT-EPPQCKDSTGKCGPPPPIDN 216
Query: 480 ASVT---VNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTIHK 536
+T ++ + S Y C+N + L G+ +TC G WS PP C + + I +
Sbjct: 217 GDITSFPLSVYAPASSVEYQCQNLYQLEGNKRITCR-NGQWS-EPPKCLHPCVISREIME 274
Query: 537 GSFVLINGTTTY------GSIAQFTCEPDYWLNGAEELVCNR--DGKWSYDIPSC 583
+ + T G A+F C+ Y L+ + DGK Y P+C
Sbjct: 275 NYNIALRWTAKQKLYLRTGESAEFVCKRGYRLSSRSHTLRTTCWDGKLEY--PTC 327
Score = 61.7 bits (143), Expect = 1e-08
Identities = 67/226 (29%), Positives = 92/226 (40%), Gaps = 20/226 (8%)
Query: 746 GALVKYRCEKGYKVIGESL---STCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNA 802
G + Y CE + +S TC + G WS TP C + C P +ENG
Sbjct: 48 GEVFYYSCEYNFVSPSKSFWTRITCTEEG-WS-PTPKCLRL-CFFPF-VENGHSESSGQT 103
Query: 803 TFYGATAFYQCDENWELEGVIRRM-CQENGTWSLEPPICK--EITCPDPSAQIKAGSGLL 859
G T C+ + L+ + C E G WS PP C+ + +C +P ++ L
Sbjct: 104 HLEGDTVQIICNTGYRLQNNENNISCVERG-WST-PPKCRSTDTSCVNPPT-VQNAHILS 160
Query: 860 VVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPID--CRSPGNIENGK 917
S G Y+C Y + G + C++ G W P C C P I+NG
Sbjct: 161 RQMSKYPSGERVRYECRSPYEMFGDEEVMCLN-GNWTEP-PQCKDSTGKCGPPPPIDNGD 218
Query: 918 IVISNGSTLF-GSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
I S SSVEY C + YQ G C +G+WS E P C
Sbjct: 219 ITSFPLSVYAPASSVEYQCQNLYQLEGNKRITC-RNGQWS-EPPKC 262
Score = 39.9 bits (89), Expect = 0.049
Identities = 21/57 (36%), Positives = 27/57 (47%), Gaps = 2/57 (3%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C +P NA + +G YEC YE+FG + C L G+WT EPP C
Sbjct: 147 CVNPPTVQNAHILSRQMSKYPSGERVRYECRSPYEMFGDEEVMC-LNGNWT-EPPQC 201
>AL049741-5|CAB53063.1| 330|Homo sapiens complement factor
H-related 1 protein.
Length = 330
Score = 79.0 bits (186), Expect = 9e-14
Identities = 86/290 (29%), Positives = 122/290 (42%), Gaps = 45/290 (15%)
Query: 626 LVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHL-GSVIQYSCTTNYRLVGPV 684
+ C ++G WS PT + + P + G E +G THL G +Q C T YRL
Sbjct: 70 ITCTEEG-WS---PTPKCLRLCFFPFVENGHSES-SGQTHLEGDTVQIICNTGYRLQNNE 124
Query: 685 RRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYR 744
E WS + P+C R +D V + H L R + Y
Sbjct: 125 NNISCVERGWS-TPPKC---RSTDTSCVNPPTV-------QNAHILSRQM------SKYP 167
Query: 745 IGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQ--YVDCGNPGRIENGKVT-LPSN 801
G V+Y C Y++ G+ C NG W+ P C+ CG P I+NG +T P +
Sbjct: 168 SGERVRYECRSPYEMFGDEEVMCL-NGNWT-EPPQCKDSTGKCGPPPPIDNGDITSFPLS 225
Query: 802 ATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVV 861
++ YQC ++LEG R C+ NG WS EPP C C S +I + +
Sbjct: 226 VYAPASSVEYQCQNLYQLEGNKRITCR-NGQWS-EPPKCLH-PCV-ISREIMENYNIALR 281
Query: 862 TST-----LSIGGEAHYQCERGYNL--KGHQTRTCISKGQWNGTV--PVC 902
+ L G A + C+RGY L + H RT W+G + P C
Sbjct: 282 WTAKQKLYLRTGESAEFVCKRGYRLSSRSHTLRTTC----WDGKLEYPTC 327
Score = 64.5 bits (150), Expect = 2e-09
Identities = 59/235 (25%), Positives = 98/235 (41%), Gaps = 25/235 (10%)
Query: 366 GNDYDVGSRIVYKCPEGHMLLGDKSR-HCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVAL 424
G + G + C G+ L +++ C + G WS PP C+ + + P + +
Sbjct: 101 GQTHLEGDTVQIICNTGYRLQNNENNISCVERG-WS-TPPKCRSTDTSCVNPPTVQNAHI 158
Query: 425 IDNRTTH---GARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDW--CPDPPAVSN 479
+ + + G R Y CR + + G+ E C + G W E P+C C PP + N
Sbjct: 159 LSRQMSKYPSGERVRYECRSPYEMFGDEEVMCLN-GNWT-EPPQCKDSTGKCGPPPPIDN 216
Query: 480 ASVT---VNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTIHK 536
+T ++ + S Y C+N + L G+ +TC G WS PP C + + I +
Sbjct: 217 GDITSFPLSVYAPASSVEYQCQNLYQLEGNKRITCR-NGQWS-EPPKCLHPCVISREIME 274
Query: 537 GSFVLINGTTTY------GSIAQFTCEPDYWLNGAEELVCNR--DGKWSYDIPSC 583
+ + T G A+F C+ Y L+ + DGK Y P+C
Sbjct: 275 NYNIALRWTAKQKLYLRTGESAEFVCKRGYRLSSRSHTLRTTCWDGKLEY--PTC 327
Score = 61.7 bits (143), Expect = 1e-08
Identities = 67/226 (29%), Positives = 92/226 (40%), Gaps = 20/226 (8%)
Query: 746 GALVKYRCEKGYKVIGESL---STCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNA 802
G + Y CE + +S TC + G WS TP C + C P +ENG
Sbjct: 48 GEVFYYSCEYNFVSPSKSFWTRITCTEEG-WS-PTPKCLRL-CFFPF-VENGHSESSGQT 103
Query: 803 TFYGATAFYQCDENWELEGVIRRM-CQENGTWSLEPPICK--EITCPDPSAQIKAGSGLL 859
G T C+ + L+ + C E G WS PP C+ + +C +P ++ L
Sbjct: 104 HLEGDTVQIICNTGYRLQNNENNISCVERG-WST-PPKCRSTDTSCVNPPT-VQNAHILS 160
Query: 860 VVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPID--CRSPGNIENGK 917
S G Y+C Y + G + C++ G W P C C P I+NG
Sbjct: 161 RQMSKYPSGERVRYECRSPYEMFGDEEVMCLN-GNWTEP-PQCKDSTGKCGPPPPIDNGD 218
Query: 918 IVISNGSTLF-GSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
I S SSVEY C + YQ G C +G+WS E P C
Sbjct: 219 ITSFPLSVYAPASSVEYQCQNLYQLEGNKRITC-RNGQWS-EPPKC 262
Score = 39.9 bits (89), Expect = 0.049
Identities = 21/57 (36%), Positives = 27/57 (47%), Gaps = 2/57 (3%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C +P NA + +G YEC YE+FG + C L G+WT EPP C
Sbjct: 147 CVNPPTVQNAHILSRQMSKYPSGERVRYECRSPYEMFGDEEVMC-LNGNWT-EPPQC 201
>X56209-1|CAA39666.1| 327|Homo sapiens FHR-1; complement factor
H-related Protein 1 protein.
Length = 327
Score = 78.6 bits (185), Expect = 1e-13
Identities = 86/289 (29%), Positives = 121/289 (41%), Gaps = 46/289 (15%)
Query: 667 GSVIQYSCTTNYRLVGP-----VRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTG 721
G V YSC Y V P R CTEE WS + P+C + C P V
Sbjct: 45 GEVFYYSC--EYNFVSPSKSFWTRINCTEE-GWSPT-PKCLRL-CFFPFV---------- 89
Query: 722 NDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIG-ESLSTCEDNGQWSGTTPTC 780
+GH+ G T+ G V+ C GY++ E+ +C + G WS T P C
Sbjct: 90 ---ENGHS-------ESSGQTHLEGDTVQIICNTGYRLQNNENNISCVERG-WS-TPPKC 137
Query: 781 QYVD--CGNPGRIENGKVTLPSNATF-YGATAFYQCDENWELEGVIRRMCQENGTWSLEP 837
+ D C NP ++N + + + G YQC +E+ G MC NG W+ EP
Sbjct: 138 RSTDTSCVNPPTVQNAYIVSRQMSKYPSGERVRYQCRSPYEMFGDEEVMCL-NGNWT-EP 195
Query: 838 PICKEITCP-DPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWN 896
P CK+ T P I G S + YQC+ Y L+G++ TC GQW+
Sbjct: 196 PQCKDSTGKCGPPPPIDNGDITSFPLSVYAPASSVEYQCQNLYQLEGNKRITC-RNGQWS 254
Query: 897 GTVPVCIPIDCRSPGNIENGKIVI--SNGSTLF---GSSVEYYCLSQYQ 940
P C+ S +EN I + + L+ G S E+ C Y+
Sbjct: 255 -EPPKCLHPCVISREIMENYNIALRWTAKQKLYLRTGESAEFVCKRGYR 302
Score = 75.8 bits (178), Expect = 8e-13
Identities = 81/288 (28%), Positives = 117/288 (40%), Gaps = 45/288 (15%)
Query: 628 CQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHL-GSVIQYSCTTNYRLVGPVRR 686
C ++G WS PT + + P + G E +G THL G +Q C T YRL
Sbjct: 69 CTEEG-WS---PTPKCLRLCFFPFVENGHSES-SGQTHLEGDTVQIICNTGYRLQNNENN 123
Query: 687 TCTEEFQWSDSSPRCE--EIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYR 744
E WS + P+C + C +P + + + +R + Y
Sbjct: 124 ISCVERGWS-TPPKCRSTDTSCVNPPTVQNAYIV-----------------SRQMSK-YP 164
Query: 745 IGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVD--CGNPGRIENGKVT-LPSN 801
G V+Y+C Y++ G+ C NG W+ P C+ CG P I+NG +T P +
Sbjct: 165 SGERVRYQCRSPYEMFGDEEVMCL-NGNWT-EPPQCKDSTGKCGPPPPIDNGDITSFPLS 222
Query: 802 ATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVV 861
++ YQC ++LEG R C+ NG WS EPP C L
Sbjct: 223 VYAPASSVEYQCQNLYQLEGNKRITCR-NGQWS-EPPKCLHPCVISREIMENYNIALRWT 280
Query: 862 TST---LSIGGEAHYQCERGYNL--KGHQTRTCISKGQWNGTV--PVC 902
L G A + C+RGY L + H RT W+G + P C
Sbjct: 281 AKQKLYLRTGESAEFVCKRGYRLSSRSHTLRTTC----WDGKLEYPTC 324
Score = 66.5 bits (155), Expect = 5e-10
Identities = 56/223 (25%), Positives = 88/223 (39%), Gaps = 19/223 (8%)
Query: 490 GSLASYTCENGHILSGS---TSVTCTLGGAWSGVPPSCKYVNCGTPTIHKGSFVLINGTT 546
G + Y+CE + T + CT G WS P + C P + G T
Sbjct: 45 GEVFYYSCEYNFVSPSKSFWTRINCTEEG-WSPTPKCLRL--CFFPFVENGHSESSGQTH 101
Query: 547 TYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELT--SCPEPEVPSGGYM---EA 601
G Q C Y L E + + WS P C T SC P Y+ +
Sbjct: 102 LEGDTVQIICNTGYRLQNNENNISCVERGWSTP-PKCRSTDTSCVNPPTVQNAYIVSRQM 160
Query: 602 FDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYID--CGKLPTLPYGTMEL 659
Y + + C + +++ G+ ++C +G W+ + P C+ CG P + G +
Sbjct: 161 SKYPSGERVRYQCRSPYEMFGDEEVMCL-NGNWT-EPPQCKDSTGKCGPPPPIDNGDITS 218
Query: 660 LNGTTHL-GSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRC 701
+ + S ++Y C Y+L G R TC QWS+ P+C
Sbjct: 219 FPLSVYAPASSVEYQCQNLYQLEGNKRITC-RNGQWSE-PPKC 259
Score = 64.9 bits (151), Expect = 1e-09
Identities = 59/235 (25%), Positives = 98/235 (41%), Gaps = 25/235 (10%)
Query: 366 GNDYDVGSRIVYKCPEGHMLLGDKSR-HCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVAL 424
G + G + C G+ L +++ C + G WS PP C+ + + P + +
Sbjct: 98 GQTHLEGDTVQIICNTGYRLQNNENNISCVERG-WS-TPPKCRSTDTSCVNPPTVQNAYI 155
Query: 425 IDNRTTH---GARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDW--CPDPPAVSN 479
+ + + G R Y CR + + G+ E C + G W E P+C C PP + N
Sbjct: 156 VSRQMSKYPSGERVRYQCRSPYEMFGDEEVMCLN-GNWT-EPPQCKDSTGKCGPPPPIDN 213
Query: 480 ASVT---VNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTIHK 536
+T ++ + S Y C+N + L G+ +TC G WS PP C + + I +
Sbjct: 214 GDITSFPLSVYAPASSVEYQCQNLYQLEGNKRITCR-NGQWS-EPPKCLHPCVISREIME 271
Query: 537 GSFVLINGTTTY------GSIAQFTCEPDYWLNGAEELVCNR--DGKWSYDIPSC 583
+ + T G A+F C+ Y L+ + DGK Y P+C
Sbjct: 272 NYNIALRWTAKQKLYLRTGESAEFVCKRGYRLSSRSHTLRTTCWDGKLEY--PTC 324
Score = 60.9 bits (141), Expect = 2e-08
Identities = 67/226 (29%), Positives = 92/226 (40%), Gaps = 20/226 (8%)
Query: 746 GALVKYRCEKGYKVIGESLST---CEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNA 802
G + Y CE + +S T C + G WS TP C + C P +ENG
Sbjct: 45 GEVFYYSCEYNFVSPSKSFWTRINCTEEG-WS-PTPKCLRL-CFFPF-VENGHSESSGQT 100
Query: 803 TFYGATAFYQCDENWELEGVIRRM-CQENGTWSLEPPICK--EITCPDPSAQIKAGSGLL 859
G T C+ + L+ + C E G WS PP C+ + +C +P ++ +
Sbjct: 101 HLEGDTVQIICNTGYRLQNNENNISCVERG-WST-PPKCRSTDTSCVNPPT-VQNAYIVS 157
Query: 860 VVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPID--CRSPGNIENGK 917
S G YQC Y + G + C++ G W P C C P I+NG
Sbjct: 158 RQMSKYPSGERVRYQCRSPYEMFGDEEVMCLN-GNWTEP-PQCKDSTGKCGPPPPIDNGD 215
Query: 918 IVISNGSTLF-GSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
I S SSVEY C + YQ G C +G+WS E P C
Sbjct: 216 ITSFPLSVYAPASSVEYQCQNLYQLEGNKRITC-RNGQWS-EPPKC 259
Score = 37.9 bits (84), Expect = 0.20
Identities = 20/57 (35%), Positives = 27/57 (47%), Gaps = 2/57 (3%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C +P NA + +G Y+C YE+FG + C L G+WT EPP C
Sbjct: 144 CVNPPTVQNAYIVSRQMSKYPSGERVRYQCRSPYEMFGDEEVMC-LNGNWT-EPPQC 198
>S82496-1|AAB37379.1| 451|Homo sapiens ETX1 protein.
Length = 451
Score = 78.6 bits (185), Expect = 1e-13
Identities = 71/279 (25%), Positives = 108/279 (38%), Gaps = 21/279 (7%)
Query: 574 GKWSYDIPSCELTSCPEPEV----PSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQ 629
G+ +D P C +V P GGY + + + + C+ G++L G L+CQ
Sbjct: 35 GESGHDTPWCSPIKVKYGDVYCRAPQGGYYKTA---LGTRCDIRCQKGYELHGSSLLICQ 91
Query: 630 QDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCT 689
+ WS D C+ C L G + ++G + S +Y C+ Y L G TC
Sbjct: 92 SNKRWS-DKVICKQKRCPTLAMPANGGFKCVDGA-YFNSRCEYYCSPGYTLKGERTVTCM 149
Query: 690 EEFQWSDSSPRC---EEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIG 746
+ WS C E R P V E+ + ++ T + RD +
Sbjct: 150 DNKAWSGRPASCVDMEPPRIKCPSVKER----IAEPNKLTVRVSWETPEGRDTADGILTD 205
Query: 747 ALVKYRCEKGYKVIGES--LSTCEDNGQWSGTTP---TCQYVDCGNPGRIENGKVTLPSN 801
++K G+ T D + GT + CG ENG + S+
Sbjct: 206 VILKGLPPGSNFPEGDHKIQYTVYDRAENKGTCKFRVKVRVKRCGKLNAPENGYMKCSSD 265
Query: 802 ATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPIC 840
YGAT + C +EL+G R+CQ N WS P C
Sbjct: 266 GDNYGATCEFSCIGGYELQGSPARVCQSNLAWSGTEPTC 304
Score = 74.9 bits (176), Expect = 1e-12
Identities = 61/239 (25%), Positives = 97/239 (40%), Gaps = 23/239 (9%)
Query: 745 IGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATF 804
+G RC+KGY++ G SL C+ N +WS C+ C NG A +
Sbjct: 68 LGTRCDIRCQKGYELHGSSLLICQSNKRWSDKV-ICKQKRCPTLAMPANGGFKCVDGA-Y 125
Query: 805 YGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKE-----ITCPDPSAQIKAGSGLL 859
+ + Y C + L+G C +N WS P C + I CP +I + L
Sbjct: 126 FNSRCEYYCSPGYTLKGERTVTCMDNKAWSGRPASCVDMEPPRIKCPSVKERIAEPNKLT 185
Query: 860 V-VTSTLSIGGEAHYQCERGYNLKG-----------HQTR-TCISKGQWNGTVPVCIPID 906
V V+ G + LKG H+ + T + + GT + +
Sbjct: 186 VRVSWETPEGRDTADGILTDVILKGLPPGSNFPEGDHKIQYTVYDRAENKGTCKFRVKVR 245
Query: 907 CRSPGNI---ENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
+ G + ENG + S+ +G++ E+ C+ Y+ G R C + WSG EP+C
Sbjct: 246 VKRCGKLNAPENGYMKCSSDGDNYGATCEFSCIGGYELQGSPARVCQSNLAWSGTEPTC 304
Score = 62.1 bits (144), Expect = 1e-08
Identities = 29/97 (29%), Positives = 47/97 (48%), Gaps = 2/97 (2%)
Query: 546 TTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFD-Y 604
T G+ C+ Y L+G+ L+C + +WS D C+ CP +P+ G + D
Sbjct: 66 TALGTRCDIRCQKGYELHGSSLLICQSNKRWS-DKVICKQKRCPTLAMPANGGFKCVDGA 124
Query: 605 YVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTC 641
Y +S ++C G+ L GE + C + WSG +C
Sbjct: 125 YFNSRCEYYCSPGYTLKGERTVTCMDNKAWSGRPASC 161
Score = 61.3 bits (142), Expect = 2e-08
Identities = 32/104 (30%), Positives = 46/104 (44%), Gaps = 4/104 (3%)
Query: 803 TFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVT 862
T G +C + +EL G +CQ N WS + ICK+ CP + + A G V
Sbjct: 66 TALGTRCDIRCQKGYELHGSSLLICQSNKRWS-DKVICKQKRCP--TLAMPANGGFKCVD 122
Query: 863 STLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPID 906
Y C GY LKG +T TC+ W+G C+ ++
Sbjct: 123 GAY-FNSRCEYYCSPGYTLKGERTVTCMDNKAWSGRPASCVDME 165
Score = 55.6 bits (128), Expect = 9e-07
Identities = 30/97 (30%), Positives = 43/97 (44%), Gaps = 2/97 (2%)
Query: 866 SIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGST 925
++G +C++GY L G C S +W+ V +C C + NG +G+
Sbjct: 67 ALGTRCDIRCQKGYELHGSSLLICQSNKRWSDKV-ICKQKRCPTLAMPANGGFKCVDGA- 124
Query: 926 LFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
F S EYYC Y G C+D+ WSG SC
Sbjct: 125 YFNSRCEYYCSPGYTLKGERTVTCMDNKAWSGRPASC 161
Score = 49.2 bits (112), Expect = 8e-05
Identities = 30/98 (30%), Positives = 40/98 (40%), Gaps = 2/98 (2%)
Query: 428 RTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVT-VNG 486
+T G R C++ + L G+ C W + C CP +N V+G
Sbjct: 65 KTALGTRCDIRCQKGYELHGSSLLICQSNKRWSDKVI-CKQKRCPTLAMPANGGFKCVDG 123
Query: 487 HKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSC 524
S Y C G+ L G +VTC AWSG P SC
Sbjct: 124 AYFNSRCEYYCSPGYTLKGERTVTCMDNKAWSGRPASC 161
Score = 48.0 bits (109), Expect = 2e-04
Identities = 30/107 (28%), Positives = 44/107 (41%), Gaps = 3/107 (2%)
Query: 490 GSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTIH-KGSFVLINGTTTY 548
G+ C+ G+ L GS+ + C WS CK C T + G F ++G +
Sbjct: 69 GTRCDIRCQKGYELHGSSLLICQSNKRWSD-KVICKQKRCPTLAMPANGGFKCVDGAY-F 126
Query: 549 GSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPS 595
S ++ C P Y L G + C + WS SC P + PS
Sbjct: 127 NSRCEYYCSPGYTLKGERTVTCMDNKAWSGRPASCVDMEPPRIKCPS 173
Score = 47.2 bits (107), Expect = 3e-04
Identities = 32/112 (28%), Positives = 46/112 (41%), Gaps = 5/112 (4%)
Query: 371 VGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRTT 430
+G+R +C +G+ L G C+ + WS CK C L +G +D
Sbjct: 68 LGTRCDIRCQKGYELHGSSLLICQSNKRWSDKV-ICKQKRCPTLAMPANGGFKCVDG-AY 125
Query: 431 HGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASV 482
+R Y C +TL G TC D W G C+ D +PP + SV
Sbjct: 126 FNSRCEYYCSPGYTLKGERTVTCMDNKAWSGRPASCV-DM--EPPRIKCPSV 174
Score = 40.3 bits (90), Expect = 0.037
Identities = 18/56 (32%), Positives = 25/56 (44%)
Query: 411 CGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRC 466
CG L E+G + + +GA +SC + L G+P R C W G P C
Sbjct: 249 CGKLNAPENGYMKCSSDGDNYGATCEFSCIGGYELQGSPARVCQSNLAWSGTEPTC 304
Score = 37.5 bits (83), Expect = 0.26
Identities = 15/44 (34%), Positives = 23/44 (52%)
Query: 485 NGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVN 528
+G G+ ++C G+ L GS + C AWSG P+C +N
Sbjct: 265 DGDNYGATCEFSCIGGYELQGSPARVCQSNLAWSGTEPTCAAMN 308
Score = 33.9 bits (74), Expect = 3.2
Identities = 15/45 (33%), Positives = 25/45 (55%), Gaps = 2/45 (4%)
Query: 366 GNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVN 410
G++Y G+ + C G+ L G +R C+ + WSG P+C +N
Sbjct: 266 GDNY--GATCEFSCIGGYELQGSPARVCQSNLAWSGTEPTCAAMN 308
>AK054913-1|BAB70826.1| 320|Homo sapiens protein ( Homo sapiens
cDNA FLJ30351 fis, clone BRACE2007641, highly similar to
Mouse mRNA for seizure-related gene product 6 type 2
precursor. ).
Length = 320
Score = 77.8 bits (183), Expect = 2e-13
Identities = 57/206 (27%), Positives = 83/206 (40%), Gaps = 29/206 (14%)
Query: 646 CGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEI- 704
C +LP +P G G+V+ Y C Y++VG C + WS+ P C+ +
Sbjct: 36 CPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVT 95
Query: 705 RCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESL 764
C DP D H LI + + +GA V+Y C++G+ + G S+
Sbjct: 96 SCHDP------------GDVEHSRRLISSP-------KFPVGATVQYICDQGFVLTGSSI 136
Query: 765 STCED----NGQWSGTTPTC---QYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENW 817
TC D + +WS P C Q C ENG + GAT + C +
Sbjct: 137 LTCHDRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSCAPGY 196
Query: 818 ELEGVIRRMCQEN--GTWSLEPPICK 841
L+G C WS PPIC+
Sbjct: 197 VLKGQASIKCVPGHPSHWSDPPPICR 222
Score = 77.0 bits (181), Expect = 3e-13
Identities = 48/165 (29%), Positives = 70/165 (42%), Gaps = 8/165 (4%)
Query: 746 GALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYV-DCGNPGRIENGKVTLPSNATF 804
G +V Y+C GY+V+G S+ C+ + WS P+CQ V C +PG +E+ + + S
Sbjct: 57 GTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVTSCHDPGDVEHSRRLISSPKFP 116
Query: 805 YGATAFYQCDENWELEGVIRRMCQE----NGTWSLEPPIC-KEITCPDPSAQIKAGSGLL 859
GAT Y CD+ + L G C + + WS P C E P
Sbjct: 117 VGATVQYICDQGFVLTGSSILTCHDRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENGARS 176
Query: 860 VVTSTLSIGGEAHYQCERGYNLKGHQTRTCI--SKGQWNGTVPVC 902
G H+ C GY LKG + C+ W+ P+C
Sbjct: 177 PEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPIC 221
Score = 76.6 bits (180), Expect = 5e-13
Identities = 49/166 (29%), Positives = 72/166 (43%), Gaps = 12/166 (7%)
Query: 372 GSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYV-NCGGLTPIEDGDVALIDNRTT 430
G+ + Y+C G+ ++G C+ D WS PSC+ V +C +E + +
Sbjct: 57 GTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVTSCHDPGDVEHSRRLISSPKFP 116
Query: 431 HGARALYSCRENFTLVGNPERTCGDEGI----WDGEAPRCLFDW---CPDPPAVSNA--S 481
GA Y C + F L G+ TC D W AP+CL + C A N S
Sbjct: 117 VGATVQYICDQGFVLTGSSILTCHDRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENGARS 176
Query: 482 VTVNGHKAGSLASYTCENGHILSGSTSVTCTLG--GAWSGVPPSCK 525
H AG+ ++C G++L G S+ C G WS PP C+
Sbjct: 177 PEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPICR 222
Score = 72.5 bits (170), Expect = 7e-12
Identities = 50/166 (30%), Positives = 75/166 (45%), Gaps = 12/166 (7%)
Query: 548 YGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCE-LTSCPEP-EVP-SGGYMEAFDY 604
+G++ + C P Y + G+ L+C D WS D+PSC+ +TSC +P +V S + + +
Sbjct: 56 HGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVTSCHDPGDVEHSRRLISSPKF 115
Query: 605 YVHSTINFHCEAGHKLIGEPNLVC--QQDG--EWSGDSPTC---EYIDCGKLPTLPYGTM 657
V +T+ + C+ G L G L C +Q G +WS +P C + C L G
Sbjct: 116 PVGATVQYICDQGFVLTGSSILTCHDRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENGAR 175
Query: 658 ELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCT--EEFQWSDSSPRC 701
G+ I +SC Y L G C WSD P C
Sbjct: 176 SPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPIC 221
Score = 66.5 bits (155), Expect = 5e-10
Identities = 55/195 (28%), Positives = 85/195 (43%), Gaps = 17/195 (8%)
Query: 462 EAPRCLFDWCPDPPAVSNASVTVNGHKA--GSLASYTCENGHILSGSTSVTCTLGGAWSG 519
E PR D CP+ P + N + + + G++ +Y C G+ + GS+ + C WS
Sbjct: 29 EVPRN--DTCPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSE 86
Query: 520 VPPSCKYV-NCGTPTIHKGSFVLINGTT-TYGSIAQFTCEPDYWLNGAEELVCN----RD 573
PSC+ V +C P + S LI+ G+ Q+ C+ + L G+ L C+
Sbjct: 87 DLPSCQRVTSCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLTGSSILTCHDRQAGS 146
Query: 574 GKWSYDIPSC---ELTSCPEPEVPSGGYM--EAFDYYVHSTINFHCEAGHKLIGEPNLVC 628
KWS P C +L C P G E + +TI+F C G+ L G+ ++ C
Sbjct: 147 PKWSDRAPKCLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKC 206
Query: 629 --QQDGEWSGDSPTC 641
WS P C
Sbjct: 207 VPGHPSHWSDPPPIC 221
Score = 64.5 bits (150), Expect = 2e-09
Identities = 49/192 (25%), Positives = 73/192 (38%), Gaps = 12/192 (6%)
Query: 785 CGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEIT 844
C I NG + +G YQC +++ G MCQ + TWS + P C+ +T
Sbjct: 36 CPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVT 95
Query: 845 -CPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTC----ISKGQWNGTV 899
C DP S L+ + +G Y C++G+ L G TC +W+
Sbjct: 96 SCHDPGD--VEHSRRLISSPKFPVGATVQYICDQGFVLTGSSILTCHDRQAGSPKWSDRA 153
Query: 900 PVCIPID---CRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCL--DDGR 954
P C+ C ENG G+++ + C Y G KC+
Sbjct: 154 PKCLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSH 213
Query: 955 WSGEEPSCELAT 966
WS P C A+
Sbjct: 214 WSDPPPICRAAS 225
Score = 61.3 bits (142), Expect = 2e-08
Identities = 49/190 (25%), Positives = 72/190 (37%), Gaps = 13/190 (6%)
Query: 411 CGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRC-LFD 469
C L I +G + HG Y C + +VG+ C + W + P C
Sbjct: 36 CPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVT 95
Query: 470 WCPDPPAVSNASVTVNGHK--AGSLASYTCENGHILSGSTSVTC--TLGGA--WSGVPPS 523
C DP V ++ ++ K G+ Y C+ G +L+GS+ +TC G+ WS P
Sbjct: 96 SCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLTGSSILTCHDRQAGSPKWSDRAPK 155
Query: 524 C---KYVNC-GTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVC--NRDGKWS 577
C + C G G+ G+ F+C P Y L G + C WS
Sbjct: 156 CLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWS 215
Query: 578 YDIPSCELTS 587
P C S
Sbjct: 216 DPPPICRAAS 225
Score = 37.9 bits (84), Expect = 0.20
Identities = 29/107 (27%), Positives = 43/107 (40%), Gaps = 9/107 (8%)
Query: 369 YDVGSRIVYKCPEGHMLLGDK--SRHCKKDGF--WSGAPPSC---KYVNCGGLTPIEDGD 421
+ VG+ + Y C +G +L G + H ++ G WS P C + C GL+ E+G
Sbjct: 115 FPVGATVQYICDQGFVLTGSSILTCHDRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENGA 174
Query: 422 VALIDNRTTHGARALYSCRENFTLVGNPERTC--GDEGIWDGEAPRC 466
+ GA +SC + L G C G W P C
Sbjct: 175 RSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPIC 221
Score = 37.1 bits (82), Expect = 0.34
Identities = 21/61 (34%), Positives = 27/61 (44%)
Query: 907 CRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCELAT 966
C I NG S + G+ V Y C YQ VG + C D WS + PSC+ T
Sbjct: 36 CPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVT 95
Query: 967 N 967
+
Sbjct: 96 S 96
Score = 35.9 bits (79), Expect = 0.79
Identities = 18/56 (32%), Positives = 29/56 (51%), Gaps = 3/56 (5%)
Query: 5 PAVP--PNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
P +P PN S P++ +V GT+ Y+C GY++ G+ C W+ + P C
Sbjct: 37 PELPEIPNGWKS-PSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSC 91
>U78093-1|AAB36685.1| 464|Homo sapiens sushi-repeat-containing
protein precursor protein.
Length = 464
Score = 77.4 bits (182), Expect = 3e-13
Identities = 66/255 (25%), Positives = 100/255 (39%), Gaps = 17/255 (6%)
Query: 594 PSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLP 653
P GGY + + + + C+ G++L G L+CQ + WS D C+ C L
Sbjct: 72 PQGGYYKTA---LGTRCDIRCQKGYELHGSSLLICQSNKRWS-DKVICKQKRCPTLAMPA 127
Query: 654 YGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRC---EEIRCSDPI 710
G + ++G + S +Y C+ Y L G TC + WS C E R P
Sbjct: 128 NGGFKCVDGA-YFNSRCEYYCSPGYTLKGERTVTCMDNKAWSGRPASCVDMEPPRIKCPS 186
Query: 711 VAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGES--LSTCE 768
V E+ + ++ T + RD + ++K G+ T
Sbjct: 187 VKER----IAEPNKLTVRVSWETPEGRDTADGILTDVILKGLPPGSNFPEGDHKIQYTVY 242
Query: 769 DNGQWSGTTP---TCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRR 825
D + GT + CG ENG + S+ YGAT + C +EL+G R
Sbjct: 243 DRAENKGTCKFRVKVRVKRCGKLNAPENGYMKCSSDGDNYGATCEFSCIGGYELQGSPAR 302
Query: 826 MCQENGTWSLEPPIC 840
+CQ N WS P C
Sbjct: 303 VCQSNLAWSGTEPTC 317
Score = 74.9 bits (176), Expect = 1e-12
Identities = 61/239 (25%), Positives = 97/239 (40%), Gaps = 23/239 (9%)
Query: 745 IGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATF 804
+G RC+KGY++ G SL C+ N +WS C+ C NG A +
Sbjct: 81 LGTRCDIRCQKGYELHGSSLLICQSNKRWSDKV-ICKQKRCPTLAMPANGGFKCVDGA-Y 138
Query: 805 YGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKE-----ITCPDPSAQIKAGSGLL 859
+ + Y C + L+G C +N WS P C + I CP +I + L
Sbjct: 139 FNSRCEYYCSPGYTLKGERTVTCMDNKAWSGRPASCVDMEPPRIKCPSVKERIAEPNKLT 198
Query: 860 V-VTSTLSIGGEAHYQCERGYNLKG-----------HQTR-TCISKGQWNGTVPVCIPID 906
V V+ G + LKG H+ + T + + GT + +
Sbjct: 199 VRVSWETPEGRDTADGILTDVILKGLPPGSNFPEGDHKIQYTVYDRAENKGTCKFRVKVR 258
Query: 907 CRSPGNI---ENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
+ G + ENG + S+ +G++ E+ C+ Y+ G R C + WSG EP+C
Sbjct: 259 VKRCGKLNAPENGYMKCSSDGDNYGATCEFSCIGGYELQGSPARVCQSNLAWSGTEPTC 317
Score = 62.1 bits (144), Expect = 1e-08
Identities = 29/97 (29%), Positives = 47/97 (48%), Gaps = 2/97 (2%)
Query: 546 TTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFD-Y 604
T G+ C+ Y L+G+ L+C + +WS D C+ CP +P+ G + D
Sbjct: 79 TALGTRCDIRCQKGYELHGSSLLICQSNKRWS-DKVICKQKRCPTLAMPANGGFKCVDGA 137
Query: 605 YVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTC 641
Y +S ++C G+ L GE + C + WSG +C
Sbjct: 138 YFNSRCEYYCSPGYTLKGERTVTCMDNKAWSGRPASC 174
Score = 61.3 bits (142), Expect = 2e-08
Identities = 32/104 (30%), Positives = 46/104 (44%), Gaps = 4/104 (3%)
Query: 803 TFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVT 862
T G +C + +EL G +CQ N WS + ICK+ CP + + A G V
Sbjct: 79 TALGTRCDIRCQKGYELHGSSLLICQSNKRWS-DKVICKQKRCP--TLAMPANGGFKCVD 135
Query: 863 STLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPID 906
Y C GY LKG +T TC+ W+G C+ ++
Sbjct: 136 GAY-FNSRCEYYCSPGYTLKGERTVTCMDNKAWSGRPASCVDME 178
Score = 55.6 bits (128), Expect = 9e-07
Identities = 30/97 (30%), Positives = 43/97 (44%), Gaps = 2/97 (2%)
Query: 866 SIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGST 925
++G +C++GY L G C S +W+ V +C C + NG +G+
Sbjct: 80 ALGTRCDIRCQKGYELHGSSLLICQSNKRWSDKV-ICKQKRCPTLAMPANGGFKCVDGA- 137
Query: 926 LFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
F S EYYC Y G C+D+ WSG SC
Sbjct: 138 YFNSRCEYYCSPGYTLKGERTVTCMDNKAWSGRPASC 174
Score = 49.2 bits (112), Expect = 8e-05
Identities = 30/98 (30%), Positives = 40/98 (40%), Gaps = 2/98 (2%)
Query: 428 RTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVT-VNG 486
+T G R C++ + L G+ C W + C CP +N V+G
Sbjct: 78 KTALGTRCDIRCQKGYELHGSSLLICQSNKRWSDKVI-CKQKRCPTLAMPANGGFKCVDG 136
Query: 487 HKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSC 524
S Y C G+ L G +VTC AWSG P SC
Sbjct: 137 AYFNSRCEYYCSPGYTLKGERTVTCMDNKAWSGRPASC 174
Score = 48.0 bits (109), Expect = 2e-04
Identities = 30/107 (28%), Positives = 44/107 (41%), Gaps = 3/107 (2%)
Query: 490 GSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTIH-KGSFVLINGTTTY 548
G+ C+ G+ L GS+ + C WS CK C T + G F ++G +
Sbjct: 82 GTRCDIRCQKGYELHGSSLLICQSNKRWSD-KVICKQKRCPTLAMPANGGFKCVDGAY-F 139
Query: 549 GSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPS 595
S ++ C P Y L G + C + WS SC P + PS
Sbjct: 140 NSRCEYYCSPGYTLKGERTVTCMDNKAWSGRPASCVDMEPPRIKCPS 186
Score = 47.2 bits (107), Expect = 3e-04
Identities = 32/112 (28%), Positives = 46/112 (41%), Gaps = 5/112 (4%)
Query: 371 VGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRTT 430
+G+R +C +G+ L G C+ + WS CK C L +G +D
Sbjct: 81 LGTRCDIRCQKGYELHGSSLLICQSNKRWSDKV-ICKQKRCPTLAMPANGGFKCVDG-AY 138
Query: 431 HGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASV 482
+R Y C +TL G TC D W G C+ D +PP + SV
Sbjct: 139 FNSRCEYYCSPGYTLKGERTVTCMDNKAWSGRPASCV-DM--EPPRIKCPSV 187
Score = 45.2 bits (102), Expect = 0.001
Identities = 23/57 (40%), Positives = 29/57 (50%), Gaps = 4/57 (7%)
Query: 588 CPEPEVPSGGYMEAF---DYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTC 641
C + P GYM+ D Y +T F C G++L G P VCQ + WSG PTC
Sbjct: 262 CGKLNAPENGYMKCSSDGDNY-GATCEFSCIGGYELQGSPARVCQSNLAWSGTEPTC 317
Score = 40.3 bits (90), Expect = 0.037
Identities = 18/56 (32%), Positives = 25/56 (44%)
Query: 411 CGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRC 466
CG L E+G + + +GA +SC + L G+P R C W G P C
Sbjct: 262 CGKLNAPENGYMKCSSDGDNYGATCEFSCIGGYELQGSPARVCQSNLAWSGTEPTC 317
Score = 37.5 bits (83), Expect = 0.26
Identities = 15/44 (34%), Positives = 23/44 (52%)
Query: 485 NGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVN 528
+G G+ ++C G+ L GS + C AWSG P+C +N
Sbjct: 278 DGDNYGATCEFSCIGGYELQGSPARVCQSNLAWSGTEPTCAAMN 321
Score = 33.9 bits (74), Expect = 3.2
Identities = 15/45 (33%), Positives = 25/45 (55%), Gaps = 2/45 (4%)
Query: 366 GNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVN 410
G++Y G+ + C G+ L G +R C+ + WSG P+C +N
Sbjct: 279 GDNY--GATCEFSCIGGYELQGSPARVCQSNLAWSGTEPTCAAMN 321
>S82496-2|AAB37378.1| 464|Homo sapiens X-linked retintis pigmentosa
candidate gene protein.
Length = 464
Score = 77.4 bits (182), Expect = 3e-13
Identities = 66/255 (25%), Positives = 100/255 (39%), Gaps = 17/255 (6%)
Query: 594 PSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLP 653
P GGY + + + + C+ G++L G L+CQ + WS D C+ C L
Sbjct: 72 PQGGYYKTA---LGTRCDIRCQKGYELHGSSLLICQSNKRWS-DKVICKQKRCPTLAMPA 127
Query: 654 YGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRC---EEIRCSDPI 710
G + ++G + S +Y C+ Y L G TC + WS C E R P
Sbjct: 128 NGGFKCVDGA-YFNSRCEYYCSPGYTLKGERTVTCMDNKAWSGRPASCVDMEPPRIKCPS 186
Query: 711 VAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGES--LSTCE 768
V E+ + ++ T + RD + ++K G+ T
Sbjct: 187 VKER----IAEPNKLTVRVSWETPEGRDTADGILTDVILKGLPPGSNFPEGDHKIQYTVY 242
Query: 769 DNGQWSGTTP---TCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRR 825
D + GT + CG ENG + S+ YGAT + C +EL+G R
Sbjct: 243 DRAENKGTCKFRVKVRVKRCGKLNAPENGYMKCSSDGDNYGATCEFSCIGGYELQGSPAR 302
Query: 826 MCQENGTWSLEPPIC 840
+CQ N WS P C
Sbjct: 303 VCQSNLAWSGTEPTC 317
Score = 74.9 bits (176), Expect = 1e-12
Identities = 61/239 (25%), Positives = 97/239 (40%), Gaps = 23/239 (9%)
Query: 745 IGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATF 804
+G RC+KGY++ G SL C+ N +WS C+ C NG A +
Sbjct: 81 LGTRCDIRCQKGYELHGSSLLICQSNKRWSDKV-ICKQKRCPTLAMPANGGFKCVDGA-Y 138
Query: 805 YGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKE-----ITCPDPSAQIKAGSGLL 859
+ + Y C + L+G C +N WS P C + I CP +I + L
Sbjct: 139 FNSRCEYYCSPGYTLKGERTVTCMDNKAWSGRPASCVDMEPPRIKCPSVKERIAEPNKLT 198
Query: 860 V-VTSTLSIGGEAHYQCERGYNLKG-----------HQTR-TCISKGQWNGTVPVCIPID 906
V V+ G + LKG H+ + T + + GT + +
Sbjct: 199 VRVSWETPEGRDTADGILTDVILKGLPPGSNFPEGDHKIQYTVYDRAENKGTCKFRVKVR 258
Query: 907 CRSPGNI---ENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
+ G + ENG + S+ +G++ E+ C+ Y+ G R C + WSG EP+C
Sbjct: 259 VKRCGKLNAPENGYMKCSSDGDNYGATCEFSCIGGYELQGSPARVCQSNLAWSGTEPTC 317
Score = 62.1 bits (144), Expect = 1e-08
Identities = 29/97 (29%), Positives = 47/97 (48%), Gaps = 2/97 (2%)
Query: 546 TTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFD-Y 604
T G+ C+ Y L+G+ L+C + +WS D C+ CP +P+ G + D
Sbjct: 79 TALGTRCDIRCQKGYELHGSSLLICQSNKRWS-DKVICKQKRCPTLAMPANGGFKCVDGA 137
Query: 605 YVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTC 641
Y +S ++C G+ L GE + C + WSG +C
Sbjct: 138 YFNSRCEYYCSPGYTLKGERTVTCMDNKAWSGRPASC 174
Score = 61.3 bits (142), Expect = 2e-08
Identities = 32/104 (30%), Positives = 46/104 (44%), Gaps = 4/104 (3%)
Query: 803 TFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVT 862
T G +C + +EL G +CQ N WS + ICK+ CP + + A G V
Sbjct: 79 TALGTRCDIRCQKGYELHGSSLLICQSNKRWS-DKVICKQKRCP--TLAMPANGGFKCVD 135
Query: 863 STLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPID 906
Y C GY LKG +T TC+ W+G C+ ++
Sbjct: 136 GAY-FNSRCEYYCSPGYTLKGERTVTCMDNKAWSGRPASCVDME 178
Score = 55.6 bits (128), Expect = 9e-07
Identities = 30/97 (30%), Positives = 43/97 (44%), Gaps = 2/97 (2%)
Query: 866 SIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGST 925
++G +C++GY L G C S +W+ V +C C + NG +G+
Sbjct: 80 ALGTRCDIRCQKGYELHGSSLLICQSNKRWSDKV-ICKQKRCPTLAMPANGGFKCVDGA- 137
Query: 926 LFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
F S EYYC Y G C+D+ WSG SC
Sbjct: 138 YFNSRCEYYCSPGYTLKGERTVTCMDNKAWSGRPASC 174
Score = 49.2 bits (112), Expect = 8e-05
Identities = 30/98 (30%), Positives = 40/98 (40%), Gaps = 2/98 (2%)
Query: 428 RTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVT-VNG 486
+T G R C++ + L G+ C W + C CP +N V+G
Sbjct: 78 KTALGTRCDIRCQKGYELHGSSLLICQSNKRWSDKVI-CKQKRCPTLAMPANGGFKCVDG 136
Query: 487 HKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSC 524
S Y C G+ L G +VTC AWSG P SC
Sbjct: 137 AYFNSRCEYYCSPGYTLKGERTVTCMDNKAWSGRPASC 174
Score = 48.0 bits (109), Expect = 2e-04
Identities = 30/107 (28%), Positives = 44/107 (41%), Gaps = 3/107 (2%)
Query: 490 GSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTIH-KGSFVLINGTTTY 548
G+ C+ G+ L GS+ + C WS CK C T + G F ++G +
Sbjct: 82 GTRCDIRCQKGYELHGSSLLICQSNKRWSD-KVICKQKRCPTLAMPANGGFKCVDGAY-F 139
Query: 549 GSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPS 595
S ++ C P Y L G + C + WS SC P + PS
Sbjct: 140 NSRCEYYCSPGYTLKGERTVTCMDNKAWSGRPASCVDMEPPRIKCPS 186
Score = 47.2 bits (107), Expect = 3e-04
Identities = 32/112 (28%), Positives = 46/112 (41%), Gaps = 5/112 (4%)
Query: 371 VGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRTT 430
+G+R +C +G+ L G C+ + WS CK C L +G +D
Sbjct: 81 LGTRCDIRCQKGYELHGSSLLICQSNKRWSDKV-ICKQKRCPTLAMPANGGFKCVDG-AY 138
Query: 431 HGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASV 482
+R Y C +TL G TC D W G C+ D +PP + SV
Sbjct: 139 FNSRCEYYCSPGYTLKGERTVTCMDNKAWSGRPASCV-DM--EPPRIKCPSV 187
Score = 45.2 bits (102), Expect = 0.001
Identities = 23/57 (40%), Positives = 29/57 (50%), Gaps = 4/57 (7%)
Query: 588 CPEPEVPSGGYMEAF---DYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTC 641
C + P GYM+ D Y +T F C G++L G P VCQ + WSG PTC
Sbjct: 262 CGKLNAPENGYMKCSSDGDNY-GATCEFSCIGGYELQGSPARVCQSNLAWSGTEPTC 317
Score = 40.3 bits (90), Expect = 0.037
Identities = 18/56 (32%), Positives = 25/56 (44%)
Query: 411 CGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRC 466
CG L E+G + + +GA +SC + L G+P R C W G P C
Sbjct: 262 CGKLNAPENGYMKCSSDGDNYGATCEFSCIGGYELQGSPARVCQSNLAWSGTEPTC 317
Score = 37.5 bits (83), Expect = 0.26
Identities = 15/44 (34%), Positives = 23/44 (52%)
Query: 485 NGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVN 528
+G G+ ++C G+ L GS + C AWSG P+C +N
Sbjct: 278 DGDNYGATCEFSCIGGYELQGSPARVCQSNLAWSGTEPTCAAMN 321
Score = 33.9 bits (74), Expect = 3.2
Identities = 15/45 (33%), Positives = 25/45 (55%), Gaps = 2/45 (4%)
Query: 366 GNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVN 410
G++Y G+ + C G+ L G +R C+ + WSG P+C +N
Sbjct: 279 GDNY--GATCEFSCIGGYELQGSPARVCQSNLAWSGTEPTCAAMN 321
>BC030816-1|AAH30816.1| 868|Homo sapiens Unknown (protein for
MGC:22782) protein.
Length = 868
Score = 77.4 bits (182), Expect = 3e-13
Identities = 44/163 (26%), Positives = 68/163 (41%), Gaps = 6/163 (3%)
Query: 752 RCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFY 811
RC G+ ++G S+ C NG WSG+ C+ C + + ++G ++ + Y T
Sbjct: 405 RCHPGFDLVGSSIILCLPNGLWSGSESYCRVRTCPHLRQPKHGHISCSTREMLYKTTCLV 464
Query: 812 QCDENWELEGVIRRMCQENGTWSLEPPICKEITCPD---PSAQIKAGSGLLVVTSTLSIG 868
CDE + LEG + CQ N W P C E C P I + G
Sbjct: 465 ACDEGYRLEGSDKLTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISPHN--CGKQPAKFG 522
Query: 869 GEAHYQCERGYNLKG-HQTRTCISKGQWNGTVPVCIPIDCRSP 910
+ C +G+ L G + C + G+WN V + D +P
Sbjct: 523 TICYVSCRQGFILSGVKEMLRCTTSGKWNVGVQAAVCKDVEAP 565
Score = 76.6 bits (180), Expect = 5e-13
Identities = 47/196 (23%), Positives = 76/196 (38%), Gaps = 7/196 (3%)
Query: 405 SCKYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAP 464
+C+ V+C L P E+G A C F LVG+ C G+W G
Sbjct: 372 TCELVHCPALKPPENGYFIQNTCNNHFNAACGVRCHPGFDLVGSSIILCLPNGLWSGSES 431
Query: 465 RCLFDWCPD--PPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPP 522
C CP P + S + + C+ G+ L GS +TC W G P
Sbjct: 432 YCRVRTCPHLRQPKHGHISCSTREMLYKTTCLVACDEGYRLEGSDKLTCQGNSQWDGPEP 491
Query: 523 SCKYVNCGTPTIHKGSFVLING----TTTYGSIAQFTCEPDYWLNGAEELV-CNRDGKWS 577
C +C T + K + + +G+I +C + L+G +E++ C GKW+
Sbjct: 492 RCVERHCSTFQMPKDVIISPHNCGKQPAKFGTICYVSCRQGFILSGVKEMLRCTTSGKWN 551
Query: 578 YDIPSCELTSCPEPEV 593
+ + P++
Sbjct: 552 VGVQAAVCKDVEAPQI 567
Score = 74.1 bits (174), Expect = 2e-12
Identities = 46/158 (29%), Positives = 68/158 (43%), Gaps = 8/158 (5%)
Query: 378 KCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRTTHGARALY 437
+C G L+G C +G WSG+ C+ C L + G ++ + L
Sbjct: 405 RCHPGFDLVGSSIILCLPNGLWSGSESYCRVRTCPHLRQPKHGHISCSTREMLYKTTCLV 464
Query: 438 SCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWC-----PDPPAVSNASVTVNGHKAGSL 492
+C E + L G+ + TC WDG PRC+ C P +S + K G++
Sbjct: 465 ACDEGYRLEGSDKLTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISPHNCGKQPAKFGTI 524
Query: 493 ASYTCENGHILSG-STSVTCTLGGAWS-GVPPS-CKYV 527
+C G ILSG + CT G W+ GV + CK V
Sbjct: 525 CYVSCRQGFILSGVKEMLRCTTSGKWNVGVQAAVCKDV 562
Score = 72.5 bits (170), Expect = 7e-12
Identities = 43/155 (27%), Positives = 64/155 (41%), Gaps = 4/155 (2%)
Query: 566 EELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYM--EAFDYYVHSTINFHCEAGHKLIGE 623
E+ VC R+G + +CEL CP + P GY + + ++ C G L+G
Sbjct: 358 EDCVC-REG-YRASGQTCELVHCPALKPPENGYFIQNTCNNHFNAACGVRCHPGFDLVGS 415
Query: 624 PNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGP 683
++C +G WSG C C L +G + + +C YRL G
Sbjct: 416 SIILCLPNGLWSGSESYCRVRTCPHLRQPKHGHISCSTREMLYKTTCLVACDEGYRLEGS 475
Query: 684 VRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVS 718
+ TC QW PRC E CS + + I+S
Sbjct: 476 DKLTCQGNSQWDGPEPRCVERHCSTFQMPKDVIIS 510
Score = 63.7 bits (148), Expect = 3e-09
Identities = 47/206 (22%), Positives = 78/206 (37%), Gaps = 8/206 (3%)
Query: 498 ENGHILSGSTSVT-CTLGGAWSGVPPSCKYVNC-GTPTIHKGSFVLINGTTTYGSIAQFT 555
EN GSTS C + +C+ V+C G F+ + +
Sbjct: 346 ENHTSPPGSTSPEDCVCREGYRASGQTCELVHCPALKPPENGYFIQNTCNNHFNAACGVR 405
Query: 556 CEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAF--DYYVHSTINFH 613
C P + L G+ ++C +G WS C + +CP P G++ + +T
Sbjct: 406 CHPGFDLVGSSIILCLPNGLWSGSESYCRVRTCPHLRQPKHGHISCSTREMLYKTTCLVA 465
Query: 614 CEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCG--KLP-TLPYGTMELLNGTTHLGSVI 670
C+ G++L G L CQ + +W G P C C ++P + G++
Sbjct: 466 CDEGYRLEGSDKLTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISPHNCGKQPAKFGTIC 525
Query: 671 QYSCTTNYRLVGPVRR-TCTEEFQWS 695
SC + L G CT +W+
Sbjct: 526 YVSCRQGFILSGVKEMLRCTTSGKWN 551
Score = 60.9 bits (141), Expect = 2e-08
Identities = 48/194 (24%), Positives = 73/194 (37%), Gaps = 8/194 (4%)
Query: 767 CEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRM 826
C + + SG T C+ V C ENG + + A +C ++L G +
Sbjct: 362 CREGYRASGQT--CELVHCPALKPPENGYFIQNTCNNHFNAACGVRCHPGFDLVGSSIIL 419
Query: 827 CQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQT 886
C NG WS C+ TCP Q K G + T + C+ GY L+G
Sbjct: 420 CLPNGLWSGSESYCRVRTCPH-LRQPKHGH-ISCSTREMLYKTTCLVACDEGYRLEGSDK 477
Query: 887 RTCISKGQWNGTVPVCIPIDC---RSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVG 943
TC QW+G P C+ C + P ++ FG+ C + G
Sbjct: 478 LTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISPHNCGKQPAKFGTICYVSCRQGFILSG 537
Query: 944 -PFLRKCLDDGRWS 956
+ +C G+W+
Sbjct: 538 VKEMLRCTTSGKWN 551
Score = 46.0 bits (104), Expect = 7e-04
Identities = 23/89 (25%), Positives = 37/89 (41%)
Query: 874 QCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEY 933
+C G++L G C+ G W+G+ C C ++G I S L+ ++
Sbjct: 405 RCHPGFDLVGSSIILCLPNGLWSGSESYCRVRTCPHLRQPKHGHISCSTREMLYKTTCLV 464
Query: 934 YCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
C Y+ G C + +W G EP C
Sbjct: 465 ACDEGYRLEGSDKLTCQGNSQWDGPEPRC 493
Score = 38.7 bits (86), Expect = 0.11
Identities = 19/78 (24%), Positives = 34/78 (43%)
Query: 889 CISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRK 948
C+ + + + C + C + ENG + + + F ++ C + VG +
Sbjct: 360 CVCREGYRASGQTCELVHCPALKPPENGYFIQNTCNNHFNAACGVRCHPGFDLVGSSIIL 419
Query: 949 CLDDGRWSGEEPSCELAT 966
CL +G WSG E C + T
Sbjct: 420 CLPNGLWSGSESYCRVRT 437
Score = 34.3 bits (75), Expect = 2.4
Identities = 18/57 (31%), Positives = 23/57 (40%), Gaps = 1/57 (1%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C H P + +S E + T V CDEGY L G+ + C W P C
Sbjct: 438 CPHLRQPKHGHISCSTREMLYKTTCLV-ACDEGYRLEGSDKLTCQGNSQWDGPEPRC 493
>BC020684-1|AAH20684.1| 464|Homo sapiens sushi-repeat-containing
protein, X-linked protein.
Length = 464
Score = 77.4 bits (182), Expect = 3e-13
Identities = 66/255 (25%), Positives = 100/255 (39%), Gaps = 17/255 (6%)
Query: 594 PSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLP 653
P GGY + + + + C+ G++L G L+CQ + WS D C+ C L
Sbjct: 72 PQGGYYKTA---LGTRCDIRCQKGYELHGSSLLICQSNKRWS-DKVICKQKRCPTLAMPA 127
Query: 654 YGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRC---EEIRCSDPI 710
G + ++G + S +Y C+ Y L G TC + WS C E R P
Sbjct: 128 NGGFKCVDGA-YFNSRCEYYCSPGYTLKGERTVTCMDNKAWSGRPASCVDMEPPRIKCPS 186
Query: 711 VAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGES--LSTCE 768
V E+ + ++ T + RD + ++K G+ T
Sbjct: 187 VKER----IAEPNKLTVRVSWETPEGRDTADGILTDVILKGLPPGSNFPEGDHKIQYTVY 242
Query: 769 DNGQWSGTTP---TCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRR 825
D + GT + CG ENG + S+ YGAT + C +EL+G R
Sbjct: 243 DRAENKGTCKFRVKVRVKRCGKLNAPENGYMKCSSDGDNYGATCEFSCIGGYELQGSPAR 302
Query: 826 MCQENGTWSLEPPIC 840
+CQ N WS P C
Sbjct: 303 VCQSNLAWSGTEPTC 317
Score = 74.9 bits (176), Expect = 1e-12
Identities = 61/239 (25%), Positives = 97/239 (40%), Gaps = 23/239 (9%)
Query: 745 IGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATF 804
+G RC+KGY++ G SL C+ N +WS C+ C NG A +
Sbjct: 81 LGTRCDIRCQKGYELHGSSLLICQSNKRWSDKV-ICKQKRCPTLAMPANGGFKCVDGA-Y 138
Query: 805 YGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKE-----ITCPDPSAQIKAGSGLL 859
+ + Y C + L+G C +N WS P C + I CP +I + L
Sbjct: 139 FNSRCEYYCSPGYTLKGERTVTCMDNKAWSGRPASCVDMEPPRIKCPSVKERIAEPNKLT 198
Query: 860 V-VTSTLSIGGEAHYQCERGYNLKG-----------HQTR-TCISKGQWNGTVPVCIPID 906
V V+ G + LKG H+ + T + + GT + +
Sbjct: 199 VRVSWETPEGRDTADGILTDVILKGLPPGSNFPEGDHKIQYTVYDRAENKGTCKFRVKVR 258
Query: 907 CRSPGNI---ENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
+ G + ENG + S+ +G++ E+ C+ Y+ G R C + WSG EP+C
Sbjct: 259 VKRCGKLNAPENGYMKCSSDGDNYGATCEFSCIGGYELQGSPARVCQSNLAWSGTEPTC 317
Score = 62.1 bits (144), Expect = 1e-08
Identities = 29/97 (29%), Positives = 47/97 (48%), Gaps = 2/97 (2%)
Query: 546 TTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFD-Y 604
T G+ C+ Y L+G+ L+C + +WS D C+ CP +P+ G + D
Sbjct: 79 TALGTRCDIRCQKGYELHGSSLLICQSNKRWS-DKVICKQKRCPTLAMPANGGFKCVDGA 137
Query: 605 YVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTC 641
Y +S ++C G+ L GE + C + WSG +C
Sbjct: 138 YFNSRCEYYCSPGYTLKGERTVTCMDNKAWSGRPASC 174
Score = 61.3 bits (142), Expect = 2e-08
Identities = 32/104 (30%), Positives = 46/104 (44%), Gaps = 4/104 (3%)
Query: 803 TFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVT 862
T G +C + +EL G +CQ N WS + ICK+ CP + + A G V
Sbjct: 79 TALGTRCDIRCQKGYELHGSSLLICQSNKRWS-DKVICKQKRCP--TLAMPANGGFKCVD 135
Query: 863 STLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPID 906
Y C GY LKG +T TC+ W+G C+ ++
Sbjct: 136 GAY-FNSRCEYYCSPGYTLKGERTVTCMDNKAWSGRPASCVDME 178
Score = 55.6 bits (128), Expect = 9e-07
Identities = 30/97 (30%), Positives = 43/97 (44%), Gaps = 2/97 (2%)
Query: 866 SIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGST 925
++G +C++GY L G C S +W+ V +C C + NG +G+
Sbjct: 80 ALGTRCDIRCQKGYELHGSSLLICQSNKRWSDKV-ICKQKRCPTLAMPANGGFKCVDGA- 137
Query: 926 LFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
F S EYYC Y G C+D+ WSG SC
Sbjct: 138 YFNSRCEYYCSPGYTLKGERTVTCMDNKAWSGRPASC 174
Score = 49.2 bits (112), Expect = 8e-05
Identities = 30/98 (30%), Positives = 40/98 (40%), Gaps = 2/98 (2%)
Query: 428 RTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVT-VNG 486
+T G R C++ + L G+ C W + C CP +N V+G
Sbjct: 78 KTALGTRCDIRCQKGYELHGSSLLICQSNKRWSDKVI-CKQKRCPTLAMPANGGFKCVDG 136
Query: 487 HKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSC 524
S Y C G+ L G +VTC AWSG P SC
Sbjct: 137 AYFNSRCEYYCSPGYTLKGERTVTCMDNKAWSGRPASC 174
Score = 48.0 bits (109), Expect = 2e-04
Identities = 30/107 (28%), Positives = 44/107 (41%), Gaps = 3/107 (2%)
Query: 490 GSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTIH-KGSFVLINGTTTY 548
G+ C+ G+ L GS+ + C WS CK C T + G F ++G +
Sbjct: 82 GTRCDIRCQKGYELHGSSLLICQSNKRWSD-KVICKQKRCPTLAMPANGGFKCVDGAY-F 139
Query: 549 GSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPS 595
S ++ C P Y L G + C + WS SC P + PS
Sbjct: 140 NSRCEYYCSPGYTLKGERTVTCMDNKAWSGRPASCVDMEPPRIKCPS 186
Score = 47.2 bits (107), Expect = 3e-04
Identities = 32/112 (28%), Positives = 46/112 (41%), Gaps = 5/112 (4%)
Query: 371 VGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRTT 430
+G+R +C +G+ L G C+ + WS CK C L +G +D
Sbjct: 81 LGTRCDIRCQKGYELHGSSLLICQSNKRWSDKV-ICKQKRCPTLAMPANGGFKCVDG-AY 138
Query: 431 HGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASV 482
+R Y C +TL G TC D W G C+ D +PP + SV
Sbjct: 139 FNSRCEYYCSPGYTLKGERTVTCMDNKAWSGRPASCV-DM--EPPRIKCPSV 187
Score = 45.2 bits (102), Expect = 0.001
Identities = 23/57 (40%), Positives = 29/57 (50%), Gaps = 4/57 (7%)
Query: 588 CPEPEVPSGGYMEAF---DYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTC 641
C + P GYM+ D Y +T F C G++L G P VCQ + WSG PTC
Sbjct: 262 CGKLNAPENGYMKCSSDGDNY-GATCEFSCIGGYELQGSPARVCQSNLAWSGTEPTC 317
Score = 40.3 bits (90), Expect = 0.037
Identities = 18/56 (32%), Positives = 25/56 (44%)
Query: 411 CGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRC 466
CG L E+G + + +GA +SC + L G+P R C W G P C
Sbjct: 262 CGKLNAPENGYMKCSSDGDNYGATCEFSCIGGYELQGSPARVCQSNLAWSGTEPTC 317
Score = 37.5 bits (83), Expect = 0.26
Identities = 15/44 (34%), Positives = 23/44 (52%)
Query: 485 NGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVN 528
+G G+ ++C G+ L GS + C AWSG P+C +N
Sbjct: 278 DGDNYGATCEFSCIGGYELQGSPARVCQSNLAWSGTEPTCAAMN 321
Score = 33.9 bits (74), Expect = 3.2
Identities = 15/45 (33%), Positives = 25/45 (55%), Gaps = 2/45 (4%)
Query: 366 GNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVN 410
G++Y G+ + C G+ L G +R C+ + WSG P+C +N
Sbjct: 279 GDNY--GATCEFSCIGGYELQGSPARVCQSNLAWSGTEPTCAAMN 321
>AL606748-1|CAI95406.1| 464|Homo sapiens sushi-repeat-containing
protein, X-linked protein.
Length = 464
Score = 77.4 bits (182), Expect = 3e-13
Identities = 66/255 (25%), Positives = 100/255 (39%), Gaps = 17/255 (6%)
Query: 594 PSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLP 653
P GGY + + + + C+ G++L G L+CQ + WS D C+ C L
Sbjct: 72 PQGGYYKTA---LGTRCDIRCQKGYELHGSSLLICQSNKRWS-DKVICKQKRCPTLAMPA 127
Query: 654 YGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRC---EEIRCSDPI 710
G + ++G + S +Y C+ Y L G TC + WS C E R P
Sbjct: 128 NGGFKCVDGA-YFNSRCEYYCSPGYTLKGERTVTCMDNKAWSGRPASCVDMEPPRIKCPS 186
Query: 711 VAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGES--LSTCE 768
V E+ + ++ T + RD + ++K G+ T
Sbjct: 187 VKER----IAEPNKLTVRVSWETPEGRDTADGILTDVILKGLPPGSNFPEGDHKIQYTVY 242
Query: 769 DNGQWSGTTP---TCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRR 825
D + GT + CG ENG + S+ YGAT + C +EL+G R
Sbjct: 243 DRAENKGTCKFRVKVRVKRCGKLNAPENGYMKCSSDGDNYGATCEFSCIGGYELQGSPAR 302
Query: 826 MCQENGTWSLEPPIC 840
+CQ N WS P C
Sbjct: 303 VCQSNLAWSGTEPTC 317
Score = 74.9 bits (176), Expect = 1e-12
Identities = 61/239 (25%), Positives = 97/239 (40%), Gaps = 23/239 (9%)
Query: 745 IGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATF 804
+G RC+KGY++ G SL C+ N +WS C+ C NG A +
Sbjct: 81 LGTRCDIRCQKGYELHGSSLLICQSNKRWSDKV-ICKQKRCPTLAMPANGGFKCVDGA-Y 138
Query: 805 YGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKE-----ITCPDPSAQIKAGSGLL 859
+ + Y C + L+G C +N WS P C + I CP +I + L
Sbjct: 139 FNSRCEYYCSPGYTLKGERTVTCMDNKAWSGRPASCVDMEPPRIKCPSVKERIAEPNKLT 198
Query: 860 V-VTSTLSIGGEAHYQCERGYNLKG-----------HQTR-TCISKGQWNGTVPVCIPID 906
V V+ G + LKG H+ + T + + GT + +
Sbjct: 199 VRVSWETPEGRDTADGILTDVILKGLPPGSNFPEGDHKIQYTVYDRAENKGTCKFRVKVR 258
Query: 907 CRSPGNI---ENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
+ G + ENG + S+ +G++ E+ C+ Y+ G R C + WSG EP+C
Sbjct: 259 VKRCGKLNAPENGYMKCSSDGDNYGATCEFSCIGGYELQGSPARVCQSNLAWSGTEPTC 317
Score = 62.1 bits (144), Expect = 1e-08
Identities = 29/97 (29%), Positives = 47/97 (48%), Gaps = 2/97 (2%)
Query: 546 TTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFD-Y 604
T G+ C+ Y L+G+ L+C + +WS D C+ CP +P+ G + D
Sbjct: 79 TALGTRCDIRCQKGYELHGSSLLICQSNKRWS-DKVICKQKRCPTLAMPANGGFKCVDGA 137
Query: 605 YVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTC 641
Y +S ++C G+ L GE + C + WSG +C
Sbjct: 138 YFNSRCEYYCSPGYTLKGERTVTCMDNKAWSGRPASC 174
Score = 61.3 bits (142), Expect = 2e-08
Identities = 32/104 (30%), Positives = 46/104 (44%), Gaps = 4/104 (3%)
Query: 803 TFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVT 862
T G +C + +EL G +CQ N WS + ICK+ CP + + A G V
Sbjct: 79 TALGTRCDIRCQKGYELHGSSLLICQSNKRWS-DKVICKQKRCP--TLAMPANGGFKCVD 135
Query: 863 STLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPID 906
Y C GY LKG +T TC+ W+G C+ ++
Sbjct: 136 GAY-FNSRCEYYCSPGYTLKGERTVTCMDNKAWSGRPASCVDME 178
Score = 55.6 bits (128), Expect = 9e-07
Identities = 30/97 (30%), Positives = 43/97 (44%), Gaps = 2/97 (2%)
Query: 866 SIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGST 925
++G +C++GY L G C S +W+ V +C C + NG +G+
Sbjct: 80 ALGTRCDIRCQKGYELHGSSLLICQSNKRWSDKV-ICKQKRCPTLAMPANGGFKCVDGA- 137
Query: 926 LFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
F S EYYC Y G C+D+ WSG SC
Sbjct: 138 YFNSRCEYYCSPGYTLKGERTVTCMDNKAWSGRPASC 174
Score = 49.2 bits (112), Expect = 8e-05
Identities = 30/98 (30%), Positives = 40/98 (40%), Gaps = 2/98 (2%)
Query: 428 RTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVT-VNG 486
+T G R C++ + L G+ C W + C CP +N V+G
Sbjct: 78 KTALGTRCDIRCQKGYELHGSSLLICQSNKRWSDKVI-CKQKRCPTLAMPANGGFKCVDG 136
Query: 487 HKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSC 524
S Y C G+ L G +VTC AWSG P SC
Sbjct: 137 AYFNSRCEYYCSPGYTLKGERTVTCMDNKAWSGRPASC 174
Score = 48.0 bits (109), Expect = 2e-04
Identities = 30/107 (28%), Positives = 44/107 (41%), Gaps = 3/107 (2%)
Query: 490 GSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTIH-KGSFVLINGTTTY 548
G+ C+ G+ L GS+ + C WS CK C T + G F ++G +
Sbjct: 82 GTRCDIRCQKGYELHGSSLLICQSNKRWSD-KVICKQKRCPTLAMPANGGFKCVDGAY-F 139
Query: 549 GSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPS 595
S ++ C P Y L G + C + WS SC P + PS
Sbjct: 140 NSRCEYYCSPGYTLKGERTVTCMDNKAWSGRPASCVDMEPPRIKCPS 186
Score = 47.2 bits (107), Expect = 3e-04
Identities = 32/112 (28%), Positives = 46/112 (41%), Gaps = 5/112 (4%)
Query: 371 VGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRTT 430
+G+R +C +G+ L G C+ + WS CK C L +G +D
Sbjct: 81 LGTRCDIRCQKGYELHGSSLLICQSNKRWSDKV-ICKQKRCPTLAMPANGGFKCVDG-AY 138
Query: 431 HGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASV 482
+R Y C +TL G TC D W G C+ D +PP + SV
Sbjct: 139 FNSRCEYYCSPGYTLKGERTVTCMDNKAWSGRPASCV-DM--EPPRIKCPSV 187
Score = 45.2 bits (102), Expect = 0.001
Identities = 23/57 (40%), Positives = 29/57 (50%), Gaps = 4/57 (7%)
Query: 588 CPEPEVPSGGYMEAF---DYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTC 641
C + P GYM+ D Y +T F C G++L G P VCQ + WSG PTC
Sbjct: 262 CGKLNAPENGYMKCSSDGDNY-GATCEFSCIGGYELQGSPARVCQSNLAWSGTEPTC 317
Score = 40.3 bits (90), Expect = 0.037
Identities = 18/56 (32%), Positives = 25/56 (44%)
Query: 411 CGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRC 466
CG L E+G + + +GA +SC + L G+P R C W G P C
Sbjct: 262 CGKLNAPENGYMKCSSDGDNYGATCEFSCIGGYELQGSPARVCQSNLAWSGTEPTC 317
Score = 37.5 bits (83), Expect = 0.26
Identities = 15/44 (34%), Positives = 23/44 (52%)
Query: 485 NGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVN 528
+G G+ ++C G+ L GS + C AWSG P+C +N
Sbjct: 278 DGDNYGATCEFSCIGGYELQGSPARVCQSNLAWSGTEPTCAAMN 321
Score = 33.9 bits (74), Expect = 3.2
Identities = 15/45 (33%), Positives = 25/45 (55%), Gaps = 2/45 (4%)
Query: 366 GNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVN 410
G++Y G+ + C G+ L G +R C+ + WSG P+C +N
Sbjct: 279 GDNY--GATCEFSCIGGYELQGSPARVCQSNLAWSGTEPTCAAMN 321
>AL592463-1|CAH73557.1| 845|Homo sapiens sushi, von Willebrand
factor type A, EGF and pentraxin domain containing 1
protein.
Length = 845
Score = 77.4 bits (182), Expect = 3e-13
Identities = 44/163 (26%), Positives = 68/163 (41%), Gaps = 6/163 (3%)
Query: 752 RCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFY 811
RC G+ ++G S+ C NG WSG+ C+ C + + ++G ++ + Y T
Sbjct: 382 RCHPGFDLVGSSIILCLPNGLWSGSESYCRVRTCPHLRQPKHGHISCSTREMLYKTTCLV 441
Query: 812 QCDENWELEGVIRRMCQENGTWSLEPPICKEITCPD---PSAQIKAGSGLLVVTSTLSIG 868
CDE + LEG + CQ N W P C E C P I + G
Sbjct: 442 ACDEGYRLEGSDKLTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISPHN--CGKQPAKFG 499
Query: 869 GEAHYQCERGYNLKG-HQTRTCISKGQWNGTVPVCIPIDCRSP 910
+ C +G+ L G + C + G+WN V + D +P
Sbjct: 500 TICYVSCRQGFILSGVKEMLRCTTSGKWNVGVQAAVCKDVEAP 542
Score = 76.6 bits (180), Expect = 5e-13
Identities = 47/196 (23%), Positives = 76/196 (38%), Gaps = 7/196 (3%)
Query: 405 SCKYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAP 464
+C+ V+C L P E+G A C F LVG+ C G+W G
Sbjct: 349 TCELVHCPALKPPENGYFIQNTCNNHFNAACGVRCHPGFDLVGSSIILCLPNGLWSGSES 408
Query: 465 RCLFDWCPD--PPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPP 522
C CP P + S + + C+ G+ L GS +TC W G P
Sbjct: 409 YCRVRTCPHLRQPKHGHISCSTREMLYKTTCLVACDEGYRLEGSDKLTCQGNSQWDGPEP 468
Query: 523 SCKYVNCGTPTIHKGSFVLING----TTTYGSIAQFTCEPDYWLNGAEELV-CNRDGKWS 577
C +C T + K + + +G+I +C + L+G +E++ C GKW+
Sbjct: 469 RCVERHCSTFQMPKDVIISPHNCGKQPAKFGTICYVSCRQGFILSGVKEMLRCTTSGKWN 528
Query: 578 YDIPSCELTSCPEPEV 593
+ + P++
Sbjct: 529 VGVQAAVCKDVEAPQI 544
Score = 74.1 bits (174), Expect = 2e-12
Identities = 46/158 (29%), Positives = 68/158 (43%), Gaps = 8/158 (5%)
Query: 378 KCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRTTHGARALY 437
+C G L+G C +G WSG+ C+ C L + G ++ + L
Sbjct: 382 RCHPGFDLVGSSIILCLPNGLWSGSESYCRVRTCPHLRQPKHGHISCSTREMLYKTTCLV 441
Query: 438 SCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWC-----PDPPAVSNASVTVNGHKAGSL 492
+C E + L G+ + TC WDG PRC+ C P +S + K G++
Sbjct: 442 ACDEGYRLEGSDKLTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISPHNCGKQPAKFGTI 501
Query: 493 ASYTCENGHILSG-STSVTCTLGGAWS-GVPPS-CKYV 527
+C G ILSG + CT G W+ GV + CK V
Sbjct: 502 CYVSCRQGFILSGVKEMLRCTTSGKWNVGVQAAVCKDV 539
Score = 72.5 bits (170), Expect = 7e-12
Identities = 43/155 (27%), Positives = 64/155 (41%), Gaps = 4/155 (2%)
Query: 566 EELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYM--EAFDYYVHSTINFHCEAGHKLIGE 623
E+ VC R+G + +CEL CP + P GY + + ++ C G L+G
Sbjct: 335 EDCVC-REG-YRASGQTCELVHCPALKPPENGYFIQNTCNNHFNAACGVRCHPGFDLVGS 392
Query: 624 PNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGP 683
++C +G WSG C C L +G + + +C YRL G
Sbjct: 393 SIILCLPNGLWSGSESYCRVRTCPHLRQPKHGHISCSTREMLYKTTCLVACDEGYRLEGS 452
Query: 684 VRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVS 718
+ TC QW PRC E CS + + I+S
Sbjct: 453 DKLTCQGNSQWDGPEPRCVERHCSTFQMPKDVIIS 487
Score = 63.7 bits (148), Expect = 3e-09
Identities = 47/206 (22%), Positives = 78/206 (37%), Gaps = 8/206 (3%)
Query: 498 ENGHILSGSTSVT-CTLGGAWSGVPPSCKYVNC-GTPTIHKGSFVLINGTTTYGSIAQFT 555
EN GSTS C + +C+ V+C G F+ + +
Sbjct: 323 ENHTSPPGSTSPEDCVCREGYRASGQTCELVHCPALKPPENGYFIQNTCNNHFNAACGVR 382
Query: 556 CEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAF--DYYVHSTINFH 613
C P + L G+ ++C +G WS C + +CP P G++ + +T
Sbjct: 383 CHPGFDLVGSSIILCLPNGLWSGSESYCRVRTCPHLRQPKHGHISCSTREMLYKTTCLVA 442
Query: 614 CEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCG--KLP-TLPYGTMELLNGTTHLGSVI 670
C+ G++L G L CQ + +W G P C C ++P + G++
Sbjct: 443 CDEGYRLEGSDKLTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISPHNCGKQPAKFGTIC 502
Query: 671 QYSCTTNYRLVGPVRR-TCTEEFQWS 695
SC + L G CT +W+
Sbjct: 503 YVSCRQGFILSGVKEMLRCTTSGKWN 528
Score = 60.9 bits (141), Expect = 2e-08
Identities = 48/194 (24%), Positives = 73/194 (37%), Gaps = 8/194 (4%)
Query: 767 CEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRM 826
C + + SG T C+ V C ENG + + A +C ++L G +
Sbjct: 339 CREGYRASGQT--CELVHCPALKPPENGYFIQNTCNNHFNAACGVRCHPGFDLVGSSIIL 396
Query: 827 CQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQT 886
C NG WS C+ TCP Q K G + T + C+ GY L+G
Sbjct: 397 CLPNGLWSGSESYCRVRTCPH-LRQPKHGH-ISCSTREMLYKTTCLVACDEGYRLEGSDK 454
Query: 887 RTCISKGQWNGTVPVCIPIDC---RSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVG 943
TC QW+G P C+ C + P ++ FG+ C + G
Sbjct: 455 LTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISPHNCGKQPAKFGTICYVSCRQGFILSG 514
Query: 944 -PFLRKCLDDGRWS 956
+ +C G+W+
Sbjct: 515 VKEMLRCTTSGKWN 528
Score = 46.0 bits (104), Expect = 7e-04
Identities = 23/89 (25%), Positives = 37/89 (41%)
Query: 874 QCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEY 933
+C G++L G C+ G W+G+ C C ++G I S L+ ++
Sbjct: 382 RCHPGFDLVGSSIILCLPNGLWSGSESYCRVRTCPHLRQPKHGHISCSTREMLYKTTCLV 441
Query: 934 YCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
C Y+ G C + +W G EP C
Sbjct: 442 ACDEGYRLEGSDKLTCQGNSQWDGPEPRC 470
Score = 38.7 bits (86), Expect = 0.11
Identities = 19/78 (24%), Positives = 34/78 (43%)
Query: 889 CISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRK 948
C+ + + + C + C + ENG + + + F ++ C + VG +
Sbjct: 337 CVCREGYRASGQTCELVHCPALKPPENGYFIQNTCNNHFNAACGVRCHPGFDLVGSSIIL 396
Query: 949 CLDDGRWSGEEPSCELAT 966
CL +G WSG E C + T
Sbjct: 397 CLPNGLWSGSESYCRVRT 414
Score = 34.3 bits (75), Expect = 2.4
Identities = 18/57 (31%), Positives = 23/57 (40%), Gaps = 1/57 (1%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C H P + +S E + T V CDEGY L G+ + C W P C
Sbjct: 415 CPHLRQPKHGHISCSTREMLYKTTCLV-ACDEGYRLEGSDKLTCQGNSQWDGPEPRC 470
>AL354982-1|CAH74138.1| 845|Homo sapiens sushi, von Willebrand
factor type A, EGF and pentraxin domain containing 1
protein.
Length = 845
Score = 77.4 bits (182), Expect = 3e-13
Identities = 44/163 (26%), Positives = 68/163 (41%), Gaps = 6/163 (3%)
Query: 752 RCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFY 811
RC G+ ++G S+ C NG WSG+ C+ C + + ++G ++ + Y T
Sbjct: 382 RCHPGFDLVGSSIILCLPNGLWSGSESYCRVRTCPHLRQPKHGHISCSTREMLYKTTCLV 441
Query: 812 QCDENWELEGVIRRMCQENGTWSLEPPICKEITCPD---PSAQIKAGSGLLVVTSTLSIG 868
CDE + LEG + CQ N W P C E C P I + G
Sbjct: 442 ACDEGYRLEGSDKLTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISPHN--CGKQPAKFG 499
Query: 869 GEAHYQCERGYNLKG-HQTRTCISKGQWNGTVPVCIPIDCRSP 910
+ C +G+ L G + C + G+WN V + D +P
Sbjct: 500 TICYVSCRQGFILSGVKEMLRCTTSGKWNVGVQAAVCKDVEAP 542
Score = 76.6 bits (180), Expect = 5e-13
Identities = 47/196 (23%), Positives = 76/196 (38%), Gaps = 7/196 (3%)
Query: 405 SCKYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAP 464
+C+ V+C L P E+G A C F LVG+ C G+W G
Sbjct: 349 TCELVHCPALKPPENGYFIQNTCNNHFNAACGVRCHPGFDLVGSSIILCLPNGLWSGSES 408
Query: 465 RCLFDWCPD--PPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPP 522
C CP P + S + + C+ G+ L GS +TC W G P
Sbjct: 409 YCRVRTCPHLRQPKHGHISCSTREMLYKTTCLVACDEGYRLEGSDKLTCQGNSQWDGPEP 468
Query: 523 SCKYVNCGTPTIHKGSFVLING----TTTYGSIAQFTCEPDYWLNGAEELV-CNRDGKWS 577
C +C T + K + + +G+I +C + L+G +E++ C GKW+
Sbjct: 469 RCVERHCSTFQMPKDVIISPHNCGKQPAKFGTICYVSCRQGFILSGVKEMLRCTTSGKWN 528
Query: 578 YDIPSCELTSCPEPEV 593
+ + P++
Sbjct: 529 VGVQAAVCKDVEAPQI 544
Score = 74.1 bits (174), Expect = 2e-12
Identities = 46/158 (29%), Positives = 68/158 (43%), Gaps = 8/158 (5%)
Query: 378 KCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRTTHGARALY 437
+C G L+G C +G WSG+ C+ C L + G ++ + L
Sbjct: 382 RCHPGFDLVGSSIILCLPNGLWSGSESYCRVRTCPHLRQPKHGHISCSTREMLYKTTCLV 441
Query: 438 SCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWC-----PDPPAVSNASVTVNGHKAGSL 492
+C E + L G+ + TC WDG PRC+ C P +S + K G++
Sbjct: 442 ACDEGYRLEGSDKLTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISPHNCGKQPAKFGTI 501
Query: 493 ASYTCENGHILSG-STSVTCTLGGAWS-GVPPS-CKYV 527
+C G ILSG + CT G W+ GV + CK V
Sbjct: 502 CYVSCRQGFILSGVKEMLRCTTSGKWNVGVQAAVCKDV 539
Score = 72.5 bits (170), Expect = 7e-12
Identities = 43/155 (27%), Positives = 64/155 (41%), Gaps = 4/155 (2%)
Query: 566 EELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYM--EAFDYYVHSTINFHCEAGHKLIGE 623
E+ VC R+G + +CEL CP + P GY + + ++ C G L+G
Sbjct: 335 EDCVC-REG-YRASGQTCELVHCPALKPPENGYFIQNTCNNHFNAACGVRCHPGFDLVGS 392
Query: 624 PNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGP 683
++C +G WSG C C L +G + + +C YRL G
Sbjct: 393 SIILCLPNGLWSGSESYCRVRTCPHLRQPKHGHISCSTREMLYKTTCLVACDEGYRLEGS 452
Query: 684 VRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVS 718
+ TC QW PRC E CS + + I+S
Sbjct: 453 DKLTCQGNSQWDGPEPRCVERHCSTFQMPKDVIIS 487
Score = 63.7 bits (148), Expect = 3e-09
Identities = 47/206 (22%), Positives = 78/206 (37%), Gaps = 8/206 (3%)
Query: 498 ENGHILSGSTSVT-CTLGGAWSGVPPSCKYVNC-GTPTIHKGSFVLINGTTTYGSIAQFT 555
EN GSTS C + +C+ V+C G F+ + +
Sbjct: 323 ENHTSPPGSTSPEDCVCREGYRASGQTCELVHCPALKPPENGYFIQNTCNNHFNAACGVR 382
Query: 556 CEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAF--DYYVHSTINFH 613
C P + L G+ ++C +G WS C + +CP P G++ + +T
Sbjct: 383 CHPGFDLVGSSIILCLPNGLWSGSESYCRVRTCPHLRQPKHGHISCSTREMLYKTTCLVA 442
Query: 614 CEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCG--KLP-TLPYGTMELLNGTTHLGSVI 670
C+ G++L G L CQ + +W G P C C ++P + G++
Sbjct: 443 CDEGYRLEGSDKLTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISPHNCGKQPAKFGTIC 502
Query: 671 QYSCTTNYRLVGPVRR-TCTEEFQWS 695
SC + L G CT +W+
Sbjct: 503 YVSCRQGFILSGVKEMLRCTTSGKWN 528
Score = 60.9 bits (141), Expect = 2e-08
Identities = 48/194 (24%), Positives = 73/194 (37%), Gaps = 8/194 (4%)
Query: 767 CEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRM 826
C + + SG T C+ V C ENG + + A +C ++L G +
Sbjct: 339 CREGYRASGQT--CELVHCPALKPPENGYFIQNTCNNHFNAACGVRCHPGFDLVGSSIIL 396
Query: 827 CQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQT 886
C NG WS C+ TCP Q K G + T + C+ GY L+G
Sbjct: 397 CLPNGLWSGSESYCRVRTCPH-LRQPKHGH-ISCSTREMLYKTTCLVACDEGYRLEGSDK 454
Query: 887 RTCISKGQWNGTVPVCIPIDC---RSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVG 943
TC QW+G P C+ C + P ++ FG+ C + G
Sbjct: 455 LTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISPHNCGKQPAKFGTICYVSCRQGFILSG 514
Query: 944 -PFLRKCLDDGRWS 956
+ +C G+W+
Sbjct: 515 VKEMLRCTTSGKWN 528
Score = 46.0 bits (104), Expect = 7e-04
Identities = 23/89 (25%), Positives = 37/89 (41%)
Query: 874 QCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEY 933
+C G++L G C+ G W+G+ C C ++G I S L+ ++
Sbjct: 382 RCHPGFDLVGSSIILCLPNGLWSGSESYCRVRTCPHLRQPKHGHISCSTREMLYKTTCLV 441
Query: 934 YCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
C Y+ G C + +W G EP C
Sbjct: 442 ACDEGYRLEGSDKLTCQGNSQWDGPEPRC 470
Score = 38.7 bits (86), Expect = 0.11
Identities = 19/78 (24%), Positives = 34/78 (43%)
Query: 889 CISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRK 948
C+ + + + C + C + ENG + + + F ++ C + VG +
Sbjct: 337 CVCREGYRASGQTCELVHCPALKPPENGYFIQNTCNNHFNAACGVRCHPGFDLVGSSIIL 396
Query: 949 CLDDGRWSGEEPSCELAT 966
CL +G WSG E C + T
Sbjct: 397 CLPNGLWSGSESYCRVRT 414
Score = 34.3 bits (75), Expect = 2.4
Identities = 18/57 (31%), Positives = 23/57 (40%), Gaps = 1/57 (1%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C H P + +S E + T V CDEGY L G+ + C W P C
Sbjct: 415 CPHLRQPKHGHISCSTREMLYKTTCLV-ACDEGYRLEGSDKLTCQGNSQWDGPEPRC 470
>U61374-1|AAB40715.1| 461|Homo sapiens protein ( Human novel
protein with short consensus repeats of six cysteines
mRNA, complete cds. ).
Length = 461
Score = 77.0 bits (181), Expect = 3e-13
Identities = 64/252 (25%), Positives = 98/252 (38%), Gaps = 13/252 (5%)
Query: 594 PSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLP 653
P GGY + + + + C+ G++L G L+CQ + WS D C+ C L
Sbjct: 71 PQGGYYKTA---LGTRCDIRCQKGYELHGSSLLICQSNKRWS-DKVICKQKRCPTLAMPA 126
Query: 654 YGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAE 713
G + ++G + S +Y C+ Y L G TC + WS +S C P +
Sbjct: 127 NGGFKCVDGA-YFNSRCEYYCSPGYTLKGERTVTCMDNKAWSGASLLC---GYGPPRIKC 182
Query: 714 KSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGES--LSTCEDNG 771
S+ + T + RD + ++K G+ T D
Sbjct: 183 PSVKERIAEPNKLTVRVWETPEGRDTADGILTDVILKGLPPGSNFPEGDHKIQYTVYDRA 242
Query: 772 QWSGTTP---TCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQ 828
+ GT + CG ENG + S+ YGAT + C +EL+G R+CQ
Sbjct: 243 ENKGTCKFRVKVRVKRCGKLNAPENGYMKCSSDGDNYGATCEFSCIGGYELQGSPARVCQ 302
Query: 829 ENGTWSLEPPIC 840
N WS P C
Sbjct: 303 SNLAWSGTEPTC 314
Score = 73.7 bits (173), Expect = 3e-12
Identities = 59/237 (24%), Positives = 94/237 (39%), Gaps = 21/237 (8%)
Query: 745 IGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATF 804
+G RC+KGY++ G SL C+ N +WS C+ C NG A +
Sbjct: 80 LGTRCDIRCQKGYELHGSSLLICQSNKRWSDKV-ICKQKRCPTLAMPANGGFKCVDGA-Y 137
Query: 805 YGATAFYQCDENWELEGVIRRMCQENGTWSLEPPIC----KEITCPDPSAQIKAGSGLLV 860
+ + Y C + L+G C +N WS +C I CP +I + L V
Sbjct: 138 FNSRCEYYCSPGYTLKGERTVTCMDNKAWSGASLLCGYGPPRIKCPSVKERIAEPNKLTV 197
Query: 861 VTSTLSIGGEAHYQCERGYNLKG-----------HQTR-TCISKGQWNGTVPVCIPIDCR 908
G + LKG H+ + T + + GT + + +
Sbjct: 198 RVWETPEGRDTADGILTDVILKGLPPGSNFPEGDHKIQYTVYDRAENKGTCKFRVKVRVK 257
Query: 909 SPGNI---ENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
G + ENG + S+ +G++ E+ C+ Y+ G R C + WSG EP+C
Sbjct: 258 RCGKLNAPENGYMKCSSDGDNYGATCEFSCIGGYELQGSPARVCQSNLAWSGTEPTC 314
Score = 64.5 bits (150), Expect = 2e-09
Identities = 31/99 (31%), Positives = 48/99 (48%), Gaps = 2/99 (2%)
Query: 546 TTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFD-Y 604
T G+ C+ Y L+G+ L+C + +WS D C+ CP +P+ G + D
Sbjct: 78 TALGTRCDIRCQKGYELHGSSLLICQSNKRWS-DKVICKQKRCPTLAMPANGGFKCVDGA 136
Query: 605 YVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEY 643
Y +S ++C G+ L GE + C + WSG S C Y
Sbjct: 137 YFNSRCEYYCSPGYTLKGERTVTCMDNKAWSGASLLCGY 175
Score = 60.1 bits (139), Expect = 4e-08
Identities = 32/100 (32%), Positives = 44/100 (44%), Gaps = 4/100 (4%)
Query: 803 TFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVT 862
T G +C + +EL G +CQ N WS + ICK+ CP + + A G V
Sbjct: 78 TALGTRCDIRCQKGYELHGSSLLICQSNKRWS-DKVICKQKRCP--TLAMPANGGFKCVD 134
Query: 863 STLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVC 902
Y C GY LKG +T TC+ W+G +C
Sbjct: 135 GAY-FNSRCEYYCSPGYTLKGERTVTCMDNKAWSGASLLC 173
Score = 52.4 bits (120), Expect = 9e-06
Identities = 29/97 (29%), Positives = 42/97 (43%), Gaps = 2/97 (2%)
Query: 866 SIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGST 925
++G +C++GY L G C S +W+ V +C C + NG +G+
Sbjct: 79 ALGTRCDIRCQKGYELHGSSLLICQSNKRWSDKV-ICKQKRCPTLAMPANGGFKCVDGA- 136
Query: 926 LFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
F S EYYC Y G C+D+ WSG C
Sbjct: 137 YFNSRCEYYCSPGYTLKGERTVTCMDNKAWSGASLLC 173
Score = 46.0 bits (104), Expect = 7e-04
Identities = 29/100 (29%), Positives = 39/100 (39%), Gaps = 2/100 (2%)
Query: 428 RTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVT-VNG 486
+T G R C++ + L G+ C W + C CP +N V+G
Sbjct: 77 KTALGTRCDIRCQKGYELHGSSLLICQSNKRWSDKVI-CKQKRCPTLAMPANGGFKCVDG 135
Query: 487 HKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKY 526
S Y C G+ L G +VTC AWSG C Y
Sbjct: 136 AYFNSRCEYYCSPGYTLKGERTVTCMDNKAWSGASLLCGY 175
Score = 45.2 bits (102), Expect = 0.001
Identities = 31/112 (27%), Positives = 45/112 (40%), Gaps = 6/112 (5%)
Query: 371 VGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRTT 430
+G+R +C +G+ L G C+ + WS CK C L +G +D
Sbjct: 80 LGTRCDIRCQKGYELHGSSLLICQSNKRWSD-KVICKQKRCPTLAMPANGGFKCVDG-AY 137
Query: 431 HGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASV 482
+R Y C +TL G TC D W G + C + PP + SV
Sbjct: 138 FNSRCEYYCSPGYTLKGERTVTCMDNKAWSGASLLCGY----GPPRIKCPSV 185
Score = 45.2 bits (102), Expect = 0.001
Identities = 23/57 (40%), Positives = 29/57 (50%), Gaps = 4/57 (7%)
Query: 588 CPEPEVPSGGYMEAF---DYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTC 641
C + P GYM+ D Y +T F C G++L G P VCQ + WSG PTC
Sbjct: 259 CGKLNAPENGYMKCSSDGDNY-GATCEFSCIGGYELQGSPARVCQSNLAWSGTEPTC 314
Score = 40.7 bits (91), Expect = 0.028
Identities = 44/179 (24%), Positives = 68/179 (37%), Gaps = 23/179 (12%)
Query: 373 SRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKY----VNCGGLTP--IEDGDVALID 426
SR Y C G+ L G+++ C + WSGA C Y + C + E + +
Sbjct: 140 SRCEYYCSPGYTLKGERTVTCMDNKAWSGASLLCGYGPPRIKCPSVKERIAEPNKLTVRV 199
Query: 427 NRTTHGARALYSCRENFTLVGNPERTCGDEG-------IWDGEAPR--CLF------DWC 471
T G + L G P + EG ++D + C F C
Sbjct: 200 WETPEGRDTADGILTDVILKGLPPGSNFPEGDHKIQYTVYDRAENKGTCKFRVKVRVKRC 259
Query: 472 PDPPAVSNASV--TVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVN 528
A N + + +G G+ ++C G+ L GS + C AWSG P+C +N
Sbjct: 260 GKLNAPENGYMKCSSDGDNYGATCEFSCIGGYELQGSPARVCQSNLAWSGTEPTCAAMN 318
Score = 33.9 bits (74), Expect = 3.2
Identities = 15/45 (33%), Positives = 25/45 (55%), Gaps = 2/45 (4%)
Query: 366 GNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVN 410
G++Y G+ + C G+ L G +R C+ + WSG P+C +N
Sbjct: 276 GDNY--GATCEFSCIGGYELQGSPARVCQSNLAWSGTEPTCAAMN 318
>AY055760-1|AAL25835.1| 419|Homo sapiens decay-accelerating factor
4ab protein.
Length = 419
Score = 77.0 bits (181), Expect = 3e-13
Identities = 45/143 (31%), Positives = 65/143 (45%), Gaps = 9/143 (6%)
Query: 766 TCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRR 825
TC N +WS C+ C NPG I NG++ +P F GAT + C+ ++L G
Sbjct: 15 TCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILF-GATISFSCNTGYKLFGSTSS 73
Query: 826 MCQENGT---WSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLK 882
C +G+ WS P C+EI CP P QI G + Y C +G+ +
Sbjct: 74 FCLISGSSVQWSDPLPECREIYCPAP-PQIDNGI-IQGERDHYGYRQSVTYACNKGFTMI 131
Query: 883 GHQTRTCI---SKGQWNGTVPVC 902
G + C +G+W+G P C
Sbjct: 132 GEHSIYCTVNNDEGEWSGPPPEC 154
Score = 77.0 bits (181), Expect = 3e-13
Identities = 44/142 (30%), Positives = 64/142 (45%), Gaps = 9/142 (6%)
Query: 827 CQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQT 886
C +N WS CK+ +CP+P +I+ +G + V + G + C GY L G +
Sbjct: 16 CLQNLKWSTAVEFCKKKSCPNPG-EIR--NGQIDVPGGILFGATISFSCNTGYKLFGSTS 72
Query: 887 RTCISKG---QWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVG 943
C+ G QW+ +P C I C +P I+NG I + SV Y C + +G
Sbjct: 73 SFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIG 132
Query: 944 PFLRKCL---DDGRWSGEEPSC 962
C D+G WSG P C
Sbjct: 133 EHSIYCTVNNDEGEWSGPPPEC 154
Score = 73.7 bits (173), Expect = 3e-12
Identities = 41/144 (28%), Positives = 63/144 (43%), Gaps = 8/144 (5%)
Query: 506 STSVTCTLGGAWSGVPPSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGA 565
S +TC WS CK +C P + + + G +G+ F+C Y L G+
Sbjct: 11 SPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGS 70
Query: 566 EELVCNRDG---KWSYDIPSCELTSCP-EPEVPSGGYMEAFDYY-VHSTINFHCEAGHKL 620
C G +WS +P C CP P++ +G D+Y ++ + C G +
Sbjct: 71 TSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTM 130
Query: 621 IGEPNLVC---QQDGEWSGDSPTC 641
IGE ++ C +GEWSG P C
Sbjct: 131 IGEHSIYCTVNNDEGEWSGPPPEC 154
Score = 72.5 bits (170), Expect = 7e-12
Identities = 49/164 (29%), Positives = 66/164 (40%), Gaps = 26/164 (15%)
Query: 624 PNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGP 683
P L C Q+ +WS C+ C + G +++ G G+ I +SC T Y+L G
Sbjct: 12 PKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGIL-FGATISFSCNTGYKLFGS 70
Query: 684 VRRTCT---EEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVG 740
C QWSD P C EI C P + I+ +R H
Sbjct: 71 TSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQ---GERDH-------------- 113
Query: 741 NTYRIGALVKYRCEKGYKVIGESLSTC---EDNGQWSGTTPTCQ 781
Y V Y C KG+ +IGE C D G+WSG P C+
Sbjct: 114 --YGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECR 155
Score = 68.9 bits (161), Expect = 9e-11
Identities = 40/142 (28%), Positives = 62/142 (43%), Gaps = 7/142 (4%)
Query: 567 ELVCNRDGKWSYDIPSCELTSCPEP-EVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPN 625
+L C ++ KWS + C+ SCP P E+ +G +TI+F C G+KL G +
Sbjct: 13 KLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTS 72
Query: 626 LVCQQDG---EWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVG 682
C G +WS P C I C P + G ++ + Y+C + ++G
Sbjct: 73 SFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIG 132
Query: 683 PVRRTCT---EEFQWSDSSPRC 701
CT +E +WS P C
Sbjct: 133 EHSIYCTVNNDEGEWSGPPPEC 154
Score = 66.1 bits (154), Expect = 6e-10
Identities = 45/157 (28%), Positives = 64/157 (40%), Gaps = 11/157 (7%)
Query: 448 NPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTV-NGHKAGSLASYTCENGHILSGS 506
+P+ TC W C CP+P + N + V G G+ S++C G+ L GS
Sbjct: 11 SPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGS 70
Query: 507 TSVTCTLGGA---WSGVPPSCKYVNC-GTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWL 562
TS C + G+ WS P C+ + C P I G Y + C + +
Sbjct: 71 TSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTM 130
Query: 563 NGAEELVC---NRDGKWSYDIPSC---ELTSCPEPEV 593
G + C N +G+WS P C LTS P V
Sbjct: 131 IGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTV 167
Score = 61.3 bits (142), Expect = 2e-08
Identities = 34/110 (30%), Positives = 51/110 (46%), Gaps = 6/110 (5%)
Query: 738 DVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNG---QWSGTTPTCQYVDCGNPGRIENG 794
DV GA + + C GYK+ G + S C +G QWS P C+ + C P +I+NG
Sbjct: 46 DVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNG 105
Query: 795 KVTLPSNATFYGATAFYQCDENWELEGVIRRMCQEN---GTWSLEPPICK 841
+ + Y + Y C++ + + G C N G WS PP C+
Sbjct: 106 IIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECR 155
Score = 56.4 bits (130), Expect = 5e-07
Identities = 33/122 (27%), Positives = 52/122 (42%), Gaps = 7/122 (5%)
Query: 352 TCGSPDKLLNTTI-LGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGF---WSGAPPSCK 407
+C +P ++ N I + G+ I + C G+ L G S C G WS P C+
Sbjct: 33 SCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECR 92
Query: 408 YVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTC---GDEGIWDGEAP 464
+ C I++G + + + Y+C + FT++G C DEG W G P
Sbjct: 93 EIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPP 152
Query: 465 RC 466
C
Sbjct: 153 EC 154
Score = 52.0 bits (119), Expect = 1e-05
Identities = 26/78 (33%), Positives = 39/78 (50%), Gaps = 4/78 (5%)
Query: 888 TCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLR 947
TC+ +W+ V C C +PG I NG+I + G LFG+++ + C + Y+ G
Sbjct: 15 TCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVP-GGILFGATISFSCNTGYKLFGSTSS 73
Query: 948 KCLDDG---RWSGEEPSC 962
CL G +WS P C
Sbjct: 74 FCLISGSSVQWSDPLPEC 91
Score = 40.7 bits (91), Expect = 0.028
Identities = 20/60 (33%), Positives = 31/60 (51%), Gaps = 5/60 (8%)
Query: 353 CGSPDKLLNTTILGNDYDVGSR--IVYKCPEGHMLLGDKSRHC---KKDGFWSGAPPSCK 407
C +P ++ N I G G R + Y C +G ++G+ S +C +G WSG PP C+
Sbjct: 96 CPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECR 155
Score = 34.3 bits (75), Expect = 2.4
Identities = 17/60 (28%), Positives = 28/60 (46%), Gaps = 5/60 (8%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRG---DWTLEPPFC 58
C +P N ++ +P I+ G + C+ GY+LFG+ C + G W+ P C
Sbjct: 34 CPNPGEIRNGQIDVPG--GILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPEC 91
>AY055759-1|AAL25834.1| 265|Homo sapiens decay-accelerating factor
3 protein.
Length = 265
Score = 77.0 bits (181), Expect = 3e-13
Identities = 45/143 (31%), Positives = 65/143 (45%), Gaps = 9/143 (6%)
Query: 766 TCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRR 825
TC N +WS C+ C NPG I NG++ +P F GAT + C+ ++L G
Sbjct: 15 TCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILF-GATISFSCNTGYKLFGSTSS 73
Query: 826 MCQENGT---WSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLK 882
C +G+ WS P C+EI CP P QI G + Y C +G+ +
Sbjct: 74 FCLISGSSVQWSDPLPECREIYCPAP-PQIDNGI-IQGERDHYGYRQSVTYACNKGFTMI 131
Query: 883 GHQTRTCI---SKGQWNGTVPVC 902
G + C +G+W+G P C
Sbjct: 132 GEHSIYCTVNNDEGEWSGPPPEC 154
Score = 77.0 bits (181), Expect = 3e-13
Identities = 44/142 (30%), Positives = 64/142 (45%), Gaps = 9/142 (6%)
Query: 827 CQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQT 886
C +N WS CK+ +CP+P +I+ +G + V + G + C GY L G +
Sbjct: 16 CLQNLKWSTAVEFCKKKSCPNPG-EIR--NGQIDVPGGILFGATISFSCNTGYKLFGSTS 72
Query: 887 RTCISKG---QWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVG 943
C+ G QW+ +P C I C +P I+NG I + SV Y C + +G
Sbjct: 73 SFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIG 132
Query: 944 PFLRKCL---DDGRWSGEEPSC 962
C D+G WSG P C
Sbjct: 133 EHSIYCTVNNDEGEWSGPPPEC 154
Score = 73.7 bits (173), Expect = 3e-12
Identities = 41/144 (28%), Positives = 63/144 (43%), Gaps = 8/144 (5%)
Query: 506 STSVTCTLGGAWSGVPPSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGA 565
S +TC WS CK +C P + + + G +G+ F+C Y L G+
Sbjct: 11 SPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGS 70
Query: 566 EELVCNRDG---KWSYDIPSCELTSCP-EPEVPSGGYMEAFDYY-VHSTINFHCEAGHKL 620
C G +WS +P C CP P++ +G D+Y ++ + C G +
Sbjct: 71 TSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTM 130
Query: 621 IGEPNLVC---QQDGEWSGDSPTC 641
IGE ++ C +GEWSG P C
Sbjct: 131 IGEHSIYCTVNNDEGEWSGPPPEC 154
Score = 72.5 bits (170), Expect = 7e-12
Identities = 49/164 (29%), Positives = 66/164 (40%), Gaps = 26/164 (15%)
Query: 624 PNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGP 683
P L C Q+ +WS C+ C + G +++ G G+ I +SC T Y+L G
Sbjct: 12 PKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGIL-FGATISFSCNTGYKLFGS 70
Query: 684 VRRTCT---EEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVG 740
C QWSD P C EI C P + I+ +R H
Sbjct: 71 TSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQ---GERDH-------------- 113
Query: 741 NTYRIGALVKYRCEKGYKVIGESLSTC---EDNGQWSGTTPTCQ 781
Y V Y C KG+ +IGE C D G+WSG P C+
Sbjct: 114 --YGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECR 155
Score = 68.9 bits (161), Expect = 9e-11
Identities = 40/142 (28%), Positives = 62/142 (43%), Gaps = 7/142 (4%)
Query: 567 ELVCNRDGKWSYDIPSCELTSCPEP-EVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPN 625
+L C ++ KWS + C+ SCP P E+ +G +TI+F C G+KL G +
Sbjct: 13 KLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTS 72
Query: 626 LVCQQDG---EWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVG 682
C G +WS P C I C P + G ++ + Y+C + ++G
Sbjct: 73 SFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIG 132
Query: 683 PVRRTCT---EEFQWSDSSPRC 701
CT +E +WS P C
Sbjct: 133 EHSIYCTVNNDEGEWSGPPPEC 154
Score = 66.1 bits (154), Expect = 6e-10
Identities = 45/157 (28%), Positives = 64/157 (40%), Gaps = 11/157 (7%)
Query: 448 NPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTV-NGHKAGSLASYTCENGHILSGS 506
+P+ TC W C CP+P + N + V G G+ S++C G+ L GS
Sbjct: 11 SPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGS 70
Query: 507 TSVTCTLGGA---WSGVPPSCKYVNC-GTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWL 562
TS C + G+ WS P C+ + C P I G Y + C + +
Sbjct: 71 TSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTM 130
Query: 563 NGAEELVC---NRDGKWSYDIPSC---ELTSCPEPEV 593
G + C N +G+WS P C LTS P V
Sbjct: 131 IGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTV 167
Score = 61.3 bits (142), Expect = 2e-08
Identities = 34/110 (30%), Positives = 51/110 (46%), Gaps = 6/110 (5%)
Query: 738 DVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNG---QWSGTTPTCQYVDCGNPGRIENG 794
DV GA + + C GYK+ G + S C +G QWS P C+ + C P +I+NG
Sbjct: 46 DVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNG 105
Query: 795 KVTLPSNATFYGATAFYQCDENWELEGVIRRMCQEN---GTWSLEPPICK 841
+ + Y + Y C++ + + G C N G WS PP C+
Sbjct: 106 IIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECR 155
Score = 56.4 bits (130), Expect = 5e-07
Identities = 33/122 (27%), Positives = 52/122 (42%), Gaps = 7/122 (5%)
Query: 352 TCGSPDKLLNTTI-LGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGF---WSGAPPSCK 407
+C +P ++ N I + G+ I + C G+ L G S C G WS P C+
Sbjct: 33 SCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECR 92
Query: 408 YVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTC---GDEGIWDGEAP 464
+ C I++G + + + Y+C + FT++G C DEG W G P
Sbjct: 93 EIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPP 152
Query: 465 RC 466
C
Sbjct: 153 EC 154
Score = 52.0 bits (119), Expect = 1e-05
Identities = 26/78 (33%), Positives = 39/78 (50%), Gaps = 4/78 (5%)
Query: 888 TCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLR 947
TC+ +W+ V C C +PG I NG+I + G LFG+++ + C + Y+ G
Sbjct: 15 TCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVP-GGILFGATISFSCNTGYKLFGSTSS 73
Query: 948 KCLDDG---RWSGEEPSC 962
CL G +WS P C
Sbjct: 74 FCLISGSSVQWSDPLPEC 91
Score = 40.7 bits (91), Expect = 0.028
Identities = 20/60 (33%), Positives = 31/60 (51%), Gaps = 5/60 (8%)
Query: 353 CGSPDKLLNTTILGNDYDVGSR--IVYKCPEGHMLLGDKSRHC---KKDGFWSGAPPSCK 407
C +P ++ N I G G R + Y C +G ++G+ S +C +G WSG PP C+
Sbjct: 96 CPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECR 155
Score = 34.3 bits (75), Expect = 2.4
Identities = 17/60 (28%), Positives = 28/60 (46%), Gaps = 5/60 (8%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRG---DWTLEPPFC 58
C +P N ++ +P I+ G + C+ GY+LFG+ C + G W+ P C
Sbjct: 34 CPNPGEIRNGQIDVPG--GILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPEC 91
>AY055758-1|AAL25833.1| 422|Homo sapiens decay-accelerating factor
1 ab protein.
Length = 422
Score = 77.0 bits (181), Expect = 3e-13
Identities = 45/143 (31%), Positives = 65/143 (45%), Gaps = 9/143 (6%)
Query: 766 TCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRR 825
TC N +WS C+ C NPG I NG++ +P F GAT + C+ ++L G
Sbjct: 15 TCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILF-GATISFSCNTGYKLFGSTSS 73
Query: 826 MCQENGT---WSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLK 882
C +G+ WS P C+EI CP P QI G + Y C +G+ +
Sbjct: 74 FCLISGSSVQWSDPLPECREIYCPAP-PQIDNGI-IQGERDHYGYRQSVTYACNKGFTMI 131
Query: 883 GHQTRTCI---SKGQWNGTVPVC 902
G + C +G+W+G P C
Sbjct: 132 GEHSIYCTVNNDEGEWSGPPPEC 154
Score = 77.0 bits (181), Expect = 3e-13
Identities = 44/142 (30%), Positives = 64/142 (45%), Gaps = 9/142 (6%)
Query: 827 CQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQT 886
C +N WS CK+ +CP+P +I+ +G + V + G + C GY L G +
Sbjct: 16 CLQNLKWSTAVEFCKKKSCPNPG-EIR--NGQIDVPGGILFGATISFSCNTGYKLFGSTS 72
Query: 887 RTCISKG---QWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVG 943
C+ G QW+ +P C I C +P I+NG I + SV Y C + +G
Sbjct: 73 SFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIG 132
Query: 944 PFLRKCL---DDGRWSGEEPSC 962
C D+G WSG P C
Sbjct: 133 EHSIYCTVNNDEGEWSGPPPEC 154
Score = 73.7 bits (173), Expect = 3e-12
Identities = 41/144 (28%), Positives = 63/144 (43%), Gaps = 8/144 (5%)
Query: 506 STSVTCTLGGAWSGVPPSCKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGA 565
S +TC WS CK +C P + + + G +G+ F+C Y L G+
Sbjct: 11 SPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGS 70
Query: 566 EELVCNRDG---KWSYDIPSCELTSCP-EPEVPSGGYMEAFDYY-VHSTINFHCEAGHKL 620
C G +WS +P C CP P++ +G D+Y ++ + C G +
Sbjct: 71 TSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTM 130
Query: 621 IGEPNLVC---QQDGEWSGDSPTC 641
IGE ++ C +GEWSG P C
Sbjct: 131 IGEHSIYCTVNNDEGEWSGPPPEC 154
Score = 72.5 bits (170), Expect = 7e-12
Identities = 49/164 (29%), Positives = 66/164 (40%), Gaps = 26/164 (15%)
Query: 624 PNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGP 683
P L C Q+ +WS C+ C + G +++ G G+ I +SC T Y+L G
Sbjct: 12 PKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGIL-FGATISFSCNTGYKLFGS 70
Query: 684 VRRTCT---EEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVG 740
C QWSD P C EI C P + I+ +R H
Sbjct: 71 TSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQ---GERDH-------------- 113
Query: 741 NTYRIGALVKYRCEKGYKVIGESLSTC---EDNGQWSGTTPTCQ 781
Y V Y C KG+ +IGE C D G+WSG P C+
Sbjct: 114 --YGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECR 155
Score = 68.9 bits (161), Expect = 9e-11
Identities = 40/142 (28%), Positives = 62/142 (43%), Gaps = 7/142 (4%)
Query: 567 ELVCNRDGKWSYDIPSCELTSCPEP-EVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPN 625
+L C ++ KWS + C+ SCP P E+ +G +TI+F C G+KL G +
Sbjct: 13 KLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTS 72
Query: 626 LVCQQDG---EWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVG 682
C G +WS P C I C P + G ++ + Y+C + ++G
Sbjct: 73 SFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIG 132
Query: 683 PVRRTCT---EEFQWSDSSPRC 701
CT +E +WS P C
Sbjct: 133 EHSIYCTVNNDEGEWSGPPPEC 154
Score = 66.1 bits (154), Expect = 6e-10
Identities = 45/157 (28%), Positives = 64/157 (40%), Gaps = 11/157 (7%)
Query: 448 NPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTV-NGHKAGSLASYTCENGHILSGS 506
+P+ TC W C CP+P + N + V G G+ S++C G+ L GS
Sbjct: 11 SPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGS 70
Query: 507 TSVTCTLGGA---WSGVPPSCKYVNC-GTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWL 562
TS C + G+ WS P C+ + C P I G Y + C + +
Sbjct: 71 TSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTM 130
Query: 563 NGAEELVC---NRDGKWSYDIPSC---ELTSCPEPEV 593
G + C N +G+WS P C LTS P V
Sbjct: 131 IGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTV 167
Score = 61.3 bits (142), Expect = 2e-08
Identities = 34/110 (30%), Positives = 51/110 (46%), Gaps = 6/110 (5%)
Query: 738 DVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNG---QWSGTTPTCQYVDCGNPGRIENG 794
DV GA + + C GYK+ G + S C +G QWS P C+ + C P +I+NG
Sbjct: 46 DVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNG 105
Query: 795 KVTLPSNATFYGATAFYQCDENWELEGVIRRMCQEN---GTWSLEPPICK 841
+ + Y + Y C++ + + G C N G WS PP C+
Sbjct: 106 IIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECR 155
Score = 56.4 bits (130), Expect = 5e-07
Identities = 33/122 (27%), Positives = 52/122 (42%), Gaps = 7/122 (5%)
Query: 352 TCGSPDKLLNTTI-LGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGF---WSGAPPSCK 407
+C +P ++ N I + G+ I + C G+ L G S C G WS P C+
Sbjct: 33 SCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECR 92
Query: 408 YVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTC---GDEGIWDGEAP 464
+ C I++G + + + Y+C + FT++G C DEG W G P
Sbjct: 93 EIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPP 152
Query: 465 RC 466
C
Sbjct: 153 EC 154
Score = 52.0 bits (119), Expect = 1e-05
Identities = 26/78 (33%), Positives = 39/78 (50%), Gaps = 4/78 (5%)
Query: 888 TCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLR 947
TC+ +W+ V C C +PG I NG+I + G LFG+++ + C + Y+ G
Sbjct: 15 TCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVP-GGILFGATISFSCNTGYKLFGSTSS 73
Query: 948 KCLDDG---RWSGEEPSC 962
CL G +WS P C
Sbjct: 74 FCLISGSSVQWSDPLPEC 91
Score = 40.7 bits (91), Expect = 0.028
Identities = 20/60 (33%), Positives = 31/60 (51%), Gaps = 5/60 (8%)
Query: 353 CGSPDKLLNTTILGNDYDVGSR--IVYKCPEGHMLLGDKSRHC---KKDGFWSGAPPSCK 407
C +P ++ N I G G R + Y C +G ++G+ S +C +G WSG PP C+
Sbjct: 96 CPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECR 155
Score = 34.3 bits (75), Expect = 2.4
Identities = 17/60 (28%), Positives = 28/60 (46%), Gaps = 5/60 (8%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRG---DWTLEPPFC 58
C +P N ++ +P I+ G + C+ GY+LFG+ C + G W+ P C
Sbjct: 34 CPNPGEIRNGQIDVPG--GILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPEC 91
>AK055383-1|BAB70912.1| 475|Homo sapiens protein ( Homo sapiens
cDNA FLJ30821 fis, clone FEBRA2001593, highly similar to
Mouse mRNA for seizure-related gene product 6 type 2
precursor. ).
Length = 475
Score = 77.0 bits (181), Expect = 3e-13
Identities = 91/382 (23%), Positives = 138/382 (36%), Gaps = 45/382 (11%)
Query: 479 NASVTVNGHKAGSLASYTCENGHILS-GSTSVTCT--LGGAWSGVPPSCKYVNCGTPTIH 535
N S + + G+ ++C+ G+ L GS + C W+ P+C+ V G T
Sbjct: 22 NFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAVCSGEITDS 81
Query: 536 KGSFVLINGTTTYGS----IAQFTCEPD--YWLNGAEELVCNRDGKWSYDIPSCELTSCP 589
G + N YG I E D L+ + D YD
Sbjct: 82 AGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPGDVLTFYDGDDLTARVLG 141
Query: 590 EPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKL 649
+ P + + F TI F + G ++G Q G C +L
Sbjct: 142 QYSGPRS-HFKLFTSMADVTIQFQSDPGTSVLG------YQQGFVIHFFEVPRNDTCPEL 194
Query: 650 PTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEI-RCSD 708
P +P G G+V+ Y C Y++VG C + WS+ P C+ + C D
Sbjct: 195 PEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVTSCHD 254
Query: 709 PIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCE 768
P D H LI + + +GA V+Y C++G+ ++G S+ TC
Sbjct: 255 P------------GDVEHSRRLISSP-------KFPVGATVQYICDQGFVLMGSSILTCH 295
Query: 769 ----DNGQWSGTTPTC---QYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEG 821
+ +WS P C Q C ENG + GAT + C + L+G
Sbjct: 296 GRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKG 355
Query: 822 VIRRMCQEN--GTWSLEPPICK 841
C WS PPIC+
Sbjct: 356 QASIKCVPGHPSHWSDPPPICR 377
Score = 76.2 bits (179), Expect = 6e-13
Identities = 49/165 (29%), Positives = 72/165 (43%), Gaps = 8/165 (4%)
Query: 746 GALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYV-DCGNPGRIENGKVTLPSNATF 804
G +V Y+C GY+V+G S+ C+ + WS P+CQ V C +PG +E+ + + S
Sbjct: 212 GTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVTSCHDPGDVEHSRRLISSPKFP 271
Query: 805 YGATAFYQCDENWELEGVIRRMC--QENGT--WSLEPPIC-KEITCPDPSAQIKAGSGLL 859
GAT Y CD+ + L G C ++ G+ WS P C E P
Sbjct: 272 VGATVQYICDQGFVLMGSSILTCHGRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENGARS 331
Query: 860 VVTSTLSIGGEAHYQCERGYNLKGHQTRTCI--SKGQWNGTVPVC 902
G H+ C GY LKG + C+ W+ P+C
Sbjct: 332 PEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPIC 376
Score = 74.1 bits (174), Expect = 2e-12
Identities = 48/166 (28%), Positives = 72/166 (43%), Gaps = 12/166 (7%)
Query: 372 GSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYV-NCGGLTPIEDGDVALIDNRTT 430
G+ + Y+C G+ ++G C+ D WS PSC+ V +C +E + +
Sbjct: 212 GTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVTSCHDPGDVEHSRRLISSPKFP 271
Query: 431 HGARALYSCRENFTLVGNPERTC----GDEGIWDGEAPRCLFDW---CPDPPAVSNA--S 481
GA Y C + F L+G+ TC W AP+CL + C A N S
Sbjct: 272 VGATVQYICDQGFVLMGSSILTCHGRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENGARS 331
Query: 482 VTVNGHKAGSLASYTCENGHILSGSTSVTCTLG--GAWSGVPPSCK 525
H AG+ ++C G++L G S+ C G WS PP C+
Sbjct: 332 PEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPICR 377
Score = 65.7 bits (153), Expect = 9e-10
Identities = 55/195 (28%), Positives = 85/195 (43%), Gaps = 17/195 (8%)
Query: 462 EAPRCLFDWCPDPPAVSNASVTVNGHKA--GSLASYTCENGHILSGSTSVTCTLGGAWSG 519
E PR D CP+ P + N + + + G++ +Y C G+ + GS+ + C WS
Sbjct: 184 EVPRN--DTCPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSE 241
Query: 520 VPPSCKYV-NCGTPTIHKGSFVLINGTT-TYGSIAQFTCEPDYWLNGAEELVCN----RD 573
PSC+ V +C P + S LI+ G+ Q+ C+ + L G+ L C+
Sbjct: 242 DLPSCQRVTSCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHGRQAGS 301
Query: 574 GKWSYDIPSC---ELTSCPEPEVPSGGYM--EAFDYYVHSTINFHCEAGHKLIGEPNLVC 628
KWS P C +L C P G E + +TI+F C G+ L G+ ++ C
Sbjct: 302 PKWSDRAPKCLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKC 361
Query: 629 --QQDGEWSGDSPTC 641
WS P C
Sbjct: 362 VPGHPSHWSDPPPIC 376
Score = 64.5 bits (150), Expect = 2e-09
Identities = 49/192 (25%), Positives = 73/192 (38%), Gaps = 12/192 (6%)
Query: 785 CGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEIT 844
C I NG + +G YQC +++ G MCQ + TWS + P C+ +T
Sbjct: 191 CPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVT 250
Query: 845 -CPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTC----ISKGQWNGTV 899
C DP S L+ + +G Y C++G+ L G TC +W+
Sbjct: 251 SCHDPGD--VEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHGRQAGSPKWSDRA 308
Query: 900 PVCIPID---CRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCL--DDGR 954
P C+ C ENG G+++ + C Y G KC+
Sbjct: 309 PKCLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSH 368
Query: 955 WSGEEPSCELAT 966
WS P C A+
Sbjct: 369 WSDPPPICRAAS 380
Score = 60.5 bits (140), Expect = 3e-08
Identities = 49/190 (25%), Positives = 71/190 (37%), Gaps = 13/190 (6%)
Query: 411 CGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRC-LFD 469
C L I +G + HG Y C + +VG+ C + W + P C
Sbjct: 191 CPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVT 250
Query: 470 WCPDPPAVSNASVTVNGHK--AGSLASYTCENGHILSGSTSVTC--TLGGA--WSGVPPS 523
C DP V ++ ++ K G+ Y C+ G +L GS+ +TC G+ WS P
Sbjct: 251 SCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHGRQAGSPKWSDRAPK 310
Query: 524 C---KYVNC-GTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAEELVC--NRDGKWS 577
C + C G G+ G+ F+C P Y L G + C WS
Sbjct: 311 CLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWS 370
Query: 578 YDIPSCELTS 587
P C S
Sbjct: 371 DPPPICRAAS 380
Score = 39.1 bits (87), Expect = 0.085
Identities = 29/107 (27%), Positives = 44/107 (41%), Gaps = 9/107 (8%)
Query: 369 YDVGSRIVYKCPEGHMLLGDK--SRHCKKDGF--WSGAPPSC---KYVNCGGLTPIEDGD 421
+ VG+ + Y C +G +L+G + H ++ G WS P C + C GL+ E+G
Sbjct: 270 FPVGATVQYICDQGFVLMGSSILTCHGRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENGA 329
Query: 422 VALIDNRTTHGARALYSCRENFTLVGNPERTC--GDEGIWDGEAPRC 466
+ GA +SC + L G C G W P C
Sbjct: 330 RSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPIC 376
Score = 37.1 bits (82), Expect = 0.34
Identities = 21/61 (34%), Positives = 27/61 (44%)
Query: 907 CRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCELAT 966
C I NG S + G+ V Y C YQ VG + C D WS + PSC+ T
Sbjct: 191 CPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVT 250
Query: 967 N 967
+
Sbjct: 251 S 251
Score = 35.9 bits (79), Expect = 0.79
Identities = 19/71 (26%), Positives = 33/71 (46%), Gaps = 4/71 (5%)
Query: 650 PTLPYGTMELLNGTTHLGSVIQYSCTTNYRL-VGPVRRTCTE--EFQWSDSSPRCEEIRC 706
P + YG T +G+ +++SC Y L G + C + + QW+++ P C + C
Sbjct: 16 PFVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAV-C 74
Query: 707 SDPIVAEKSIV 717
S I +V
Sbjct: 75 SGEITDSAGVV 85
Score = 35.9 bits (79), Expect = 0.79
Identities = 18/56 (32%), Positives = 29/56 (51%), Gaps = 3/56 (5%)
Query: 5 PAVP--PNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
P +P PN S P++ +V GT+ Y+C GY++ G+ C W+ + P C
Sbjct: 192 PELPEIPNGWKS-PSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSC 246
Score = 33.1 bits (72), Expect = 5.6
Identities = 17/59 (28%), Positives = 27/59 (45%), Gaps = 3/59 (5%)
Query: 528 NCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAE---ELVCNRDGKWSYDIPSC 583
+C P + G+F T G+ +F+C+P Y L E V D +W+ P+C
Sbjct: 12 HCYEPFVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPAC 70
>AK027870-1|BAB55420.1| 1316|Homo sapiens protein ( Homo sapiens
cDNA FLJ14964 fis, clone PLACE4000581, moderately
similar to FIBROPELLIN I PRECURSOR. ).
Length = 1316
Score = 76.6 bits (180), Expect = 5e-13
Identities = 44/163 (26%), Positives = 67/163 (41%), Gaps = 6/163 (3%)
Query: 752 RCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFY 811
RC G+ ++G S+ C NG WSG C+ C + + ++G ++ + Y T
Sbjct: 172 RCHPGFDLVGSSIILCLPNGLWSGLESYCRVRTCPHLRQPKHGHISCSTREMLYKTTCLV 231
Query: 812 QCDENWELEGVIRRMCQENGTWSLEPPICKEITCPD---PSAQIKAGSGLLVVTSTLSIG 868
CDE + LEG + CQ N W P C E C P I + G
Sbjct: 232 ACDEGYRLEGSDKLTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISPHN--CGKQPAKFG 289
Query: 869 GEAHYQCERGYNLKG-HQTRTCISKGQWNGTVPVCIPIDCRSP 910
+ C +G+ L G + C + G+WN V + D +P
Sbjct: 290 TICYVSCRQGFILSGVKEMLRCTTSGKWNVGVQAAVCKDVEAP 332
Score = 75.4 bits (177), Expect = 1e-12
Identities = 47/196 (23%), Positives = 76/196 (38%), Gaps = 7/196 (3%)
Query: 405 SCKYVNCGGLTPIEDGDVALIDNRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAP 464
+C+ V+C L P E+G A C F LVG+ C G+W G
Sbjct: 139 TCELVHCPALKPPENGYFIQNTCNNHFNAACGVRCHPGFDLVGSSIILCLPNGLWSGLES 198
Query: 465 RCLFDWCPD--PPAVSNASVTVNGHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPP 522
C CP P + S + + C+ G+ L GS +TC W G P
Sbjct: 199 YCRVRTCPHLRQPKHGHISCSTREMLYKTTCLVACDEGYRLEGSDKLTCQGNSQWDGPEP 258
Query: 523 SCKYVNCGTPTIHKGSFVLING----TTTYGSIAQFTCEPDYWLNGAEELV-CNRDGKWS 577
C +C T + K + + +G+I +C + L+G +E++ C GKW+
Sbjct: 259 RCVERHCSTFQMPKDVIISPHNCGKQPAKFGTICYVSCRQGFILSGVKEMLRCTTSGKWN 318
Query: 578 YDIPSCELTSCPEPEV 593
+ + P++
Sbjct: 319 VGVQAAVCKDVEAPQI 334
Score = 73.3 bits (172), Expect = 4e-12
Identities = 46/158 (29%), Positives = 67/158 (42%), Gaps = 8/158 (5%)
Query: 378 KCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVALIDNRTTHGARALY 437
+C G L+G C +G WSG C+ C L + G ++ + L
Sbjct: 172 RCHPGFDLVGSSIILCLPNGLWSGLESYCRVRTCPHLRQPKHGHISCSTREMLYKTTCLV 231
Query: 438 SCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWC-----PDPPAVSNASVTVNGHKAGSL 492
+C E + L G+ + TC WDG PRC+ C P +S + K G++
Sbjct: 232 ACDEGYRLEGSDKLTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISPHNCGKQPAKFGTI 291
Query: 493 ASYTCENGHILSG-STSVTCTLGGAWS-GVPPS-CKYV 527
+C G ILSG + CT G W+ GV + CK V
Sbjct: 292 CYVSCRQGFILSGVKEMLRCTTSGKWNVGVQAAVCKDV 329
Score = 70.9 bits (166), Expect = 2e-11
Identities = 43/155 (27%), Positives = 64/155 (41%), Gaps = 4/155 (2%)
Query: 566 EELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYM--EAFDYYVHSTINFHCEAGHKLIGE 623
E+ VC R+G + +CEL CP + P GY + + ++ C G L+G
Sbjct: 125 EDCVC-REG-YRASGQTCELVHCPALKPPENGYFIQNTCNNHFNAACGVRCHPGFDLVGS 182
Query: 624 PNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGP 683
++C +G WSG C C L +G + + +C YRL G
Sbjct: 183 SIILCLPNGLWSGLESYCRVRTCPHLRQPKHGHISCSTREMLYKTTCLVACDEGYRLEGS 242
Query: 684 VRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVS 718
+ TC QW PRC E CS + + I+S
Sbjct: 243 DKLTCQGNSQWDGPEPRCVERHCSTFQMPKDVIIS 277
Score = 62.1 bits (144), Expect = 1e-08
Identities = 47/206 (22%), Positives = 78/206 (37%), Gaps = 8/206 (3%)
Query: 498 ENGHILSGSTSVT-CTLGGAWSGVPPSCKYVNC-GTPTIHKGSFVLINGTTTYGSIAQFT 555
EN GSTS C + +C+ V+C G F+ + +
Sbjct: 113 ENHTSPPGSTSPEDCVCREGYRASGQTCELVHCPALKPPENGYFIQNTCNNHFNAACGVR 172
Query: 556 CEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAF--DYYVHSTINFH 613
C P + L G+ ++C +G WS C + +CP P G++ + +T
Sbjct: 173 CHPGFDLVGSSIILCLPNGLWSGLESYCRVRTCPHLRQPKHGHISCSTREMLYKTTCLVA 232
Query: 614 CEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCG--KLP-TLPYGTMELLNGTTHLGSVI 670
C+ G++L G L CQ + +W G P C C ++P + G++
Sbjct: 233 CDEGYRLEGSDKLTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISPHNCGKQPAKFGTIC 292
Query: 671 QYSCTTNYRLVGPVRR-TCTEEFQWS 695
SC + L G CT +W+
Sbjct: 293 YVSCRQGFILSGVKEMLRCTTSGKWN 318
Score = 59.7 bits (138), Expect = 6e-08
Identities = 48/194 (24%), Positives = 73/194 (37%), Gaps = 8/194 (4%)
Query: 767 CEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVIRRM 826
C + + SG T C+ V C ENG + + A +C ++L G +
Sbjct: 129 CREGYRASGQT--CELVHCPALKPPENGYFIQNTCNNHFNAACGVRCHPGFDLVGSSIIL 186
Query: 827 CQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQT 886
C NG WS C+ TCP Q K G + T + C+ GY L+G
Sbjct: 187 CLPNGLWSGLESYCRVRTCPH-LRQPKHGH-ISCSTREMLYKTTCLVACDEGYRLEGSDK 244
Query: 887 RTCISKGQWNGTVPVCIPIDC---RSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVG 943
TC QW+G P C+ C + P ++ FG+ C + G
Sbjct: 245 LTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISPHNCGKQPAKFGTICYVSCRQGFILSG 304
Query: 944 -PFLRKCLDDGRWS 956
+ +C G+W+
Sbjct: 305 VKEMLRCTTSGKWN 318
Score = 45.2 bits (102), Expect = 0.001
Identities = 23/89 (25%), Positives = 36/89 (40%)
Query: 874 QCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEY 933
+C G++L G C+ G W+G C C ++G I S L+ ++
Sbjct: 172 RCHPGFDLVGSSIILCLPNGLWSGLESYCRVRTCPHLRQPKHGHISCSTREMLYKTTCLV 231
Query: 934 YCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
C Y+ G C + +W G EP C
Sbjct: 232 ACDEGYRLEGSDKLTCQGNSQWDGPEPRC 260
Score = 37.5 bits (83), Expect = 0.26
Identities = 19/78 (24%), Positives = 34/78 (43%)
Query: 889 CISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLFGSSVEYYCLSQYQRVGPFLRK 948
C+ + + + C + C + ENG + + + F ++ C + VG +
Sbjct: 127 CVCREGYRASGQTCELVHCPALKPPENGYFIQNTCNNHFNAACGVRCHPGFDLVGSSIIL 186
Query: 949 CLDDGRWSGEEPSCELAT 966
CL +G WSG E C + T
Sbjct: 187 CLPNGLWSGLESYCRVRT 204
Score = 34.3 bits (75), Expect = 2.4
Identities = 18/57 (31%), Positives = 23/57 (40%), Gaps = 1/57 (1%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C H P + +S E + T V CDEGY L G+ + C W P C
Sbjct: 205 CPHLRQPKHGHISCSTREMLYKTTCLV-ACDEGYRLEGSDKLTCQGNSQWDGPEPRC 260
>AC005254-1|AAC25581.1| 315|Homo sapiens PGCN_HUMAN, PARTIAL CDS
protein.
Length = 315
Score = 76.6 bits (180), Expect = 5e-13
Identities = 48/182 (26%), Positives = 83/182 (45%), Gaps = 16/182 (8%)
Query: 222 FSRNCYEFNVARGGSFDEARKQCQSHGGDLIHGFQGATSSFLTQELERRKAQLKTQLVWI 281
F +CY + A ++++A K C+ G L SF+ + WI
Sbjct: 89 FQGHCYRY-FAHRRAWEDAEKDCRRRSGHLTSVHSPEEHSFINS--------FGHENTWI 139
Query: 282 GAQKEPGLTSRTWQWVDGELVSKPSWGKDQPNNY-NGEQNCVVLDGGRGWLWNDVGCNLD 340
G + R +QW D + +W ++QP+N+ G ++CVV+ WNDV CN +
Sbjct: 140 GLNDR--IVERDFQWTDNTGLQFENWRENQPDNFFAGGEDCVVMVAHESGRWNDVPCNYN 197
Query: 341 YLHWICQYLPPTCGSPDKLLNTTILG---NDYDVGSRIVYKCPEGHMLLGDKSRHCKKDG 397
L ++C+ CG P + N +++G Y+V + + Y+C EG + C+ +G
Sbjct: 198 -LPYVCKKGTVLCGPPPAVENASLIGARKAKYNVHATVRYQCNEGFAQHHVATIRCRSNG 256
Query: 398 FW 399
W
Sbjct: 257 KW 258
Score = 36.7 bits (81), Expect = 0.45
Identities = 18/57 (31%), Positives = 25/57 (43%), Gaps = 1/57 (1%)
Query: 785 CGNPGRIENGKVTLPSNATF-YGATAFYQCDENWELEGVIRRMCQENGTWSLEPPIC 840
CG P +EN + A + AT YQC+E + V C+ NG W +C
Sbjct: 209 CGPPPAVENASLIGARKAKYNVHATVRYQCNEGFAQHHVATIRCRSNGKWDRPQIVC 265
Score = 35.5 bits (78), Expect = 1.0
Identities = 25/99 (25%), Positives = 45/99 (45%), Gaps = 14/99 (14%)
Query: 557 EPDYWLNGAEE---LVCNRDGKWS-----YDIPS-CELTS--C-PEPEVPSGGYMEA--F 602
+PD + G E+ +V + G+W+ Y++P C+ + C P P V + + A
Sbjct: 167 QPDNFFAGGEDCVVMVAHESGRWNDVPCNYNLPYVCKKGTVLCGPPPAVENASLIGARKA 226
Query: 603 DYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTC 641
Y VH+T+ + C G + C+ +G+W C
Sbjct: 227 KYNVHATVRYQCNEGFAQHHVATIRCRSNGKWDRPQIVC 265
>AB210004-1|BAE06086.1| 1335|Homo sapiens CSPG3 variant protein
protein.
Length = 1335
Score = 76.6 bits (180), Expect = 5e-13
Identities = 48/182 (26%), Positives = 83/182 (45%), Gaps = 16/182 (8%)
Query: 222 FSRNCYEFNVARGGSFDEARKQCQSHGGDLIHGFQGATSSFLTQELERRKAQLKTQLVWI 281
F +CY + A ++++A K C+ G L SF+ + WI
Sbjct: 1109 FQGHCYRY-FAHRRAWEDAEKDCRRRSGHLTSVHSPEEHSFINS--------FGHENTWI 1159
Query: 282 GAQKEPGLTSRTWQWVDGELVSKPSWGKDQPNNY-NGEQNCVVLDGGRGWLWNDVGCNLD 340
G + R +QW D + +W ++QP+N+ G ++CVV+ WNDV CN +
Sbjct: 1160 GLNDR--IVERDFQWTDNTGLQFENWRENQPDNFFAGGEDCVVMVAHESGRWNDVPCNYN 1217
Query: 341 YLHWICQYLPPTCGSPDKLLNTTILG---NDYDVGSRIVYKCPEGHMLLGDKSRHCKKDG 397
L ++C+ CG P + N +++G Y+V + + Y+C EG + C+ +G
Sbjct: 1218 -LPYVCKKGTVLCGPPPAVENASLIGARKAKYNVHATVRYQCNEGFAQHHVATIRCRSNG 1276
Query: 398 FW 399
W
Sbjct: 1277 KW 1278
Score = 36.7 bits (81), Expect = 0.45
Identities = 18/57 (31%), Positives = 25/57 (43%), Gaps = 1/57 (1%)
Query: 785 CGNPGRIENGKVTLPSNATF-YGATAFYQCDENWELEGVIRRMCQENGTWSLEPPIC 840
CG P +EN + A + AT YQC+E + V C+ NG W +C
Sbjct: 1229 CGPPPAVENASLIGARKAKYNVHATVRYQCNEGFAQHHVATIRCRSNGKWDRPQIVC 1285
Score = 35.5 bits (78), Expect = 1.0
Identities = 25/99 (25%), Positives = 45/99 (45%), Gaps = 14/99 (14%)
Query: 557 EPDYWLNGAEE---LVCNRDGKWS-----YDIPS-CELTS--C-PEPEVPSGGYMEA--F 602
+PD + G E+ +V + G+W+ Y++P C+ + C P P V + + A
Sbjct: 1187 QPDNFFAGGEDCVVMVAHESGRWNDVPCNYNLPYVCKKGTVLCGPPPAVENASLIGARKA 1246
Query: 603 DYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTC 641
Y VH+T+ + C G + C+ +G+W C
Sbjct: 1247 KYNVHATVRYQCNEGFAQHHVATIRCRSNGKWDRPQIVC 1285
>AL359979-1|CAI12801.1| 490|Homo sapiens sushi domain containing 4
protein.
Length = 490
Score = 73.7 bits (173), Expect = 3e-12
Identities = 67/236 (28%), Positives = 99/236 (41%), Gaps = 28/236 (11%)
Query: 366 GNDYDVGSRIVYKCPEGHMLLGDKSRHCKK--DGFWSGAPPS---CKYVNCGGLTPIEDG 420
G + GS + C +G L G R C K +G P C +C + IED
Sbjct: 72 GGVFFEGSVARFHCQDGFKLKGATKRLCLKHFNGTLGWIPSDNSICVQEDCR-IPQIEDA 130
Query: 421 DVALIDNRT-THGARALYSCRENFTL----VGNPERTCGDEGIWDGEAPRCLFDWCPDPP 475
+ I N+T HG + + +C E F + + N C D+G W+ P C C P
Sbjct: 131 E---IHNKTYRHGEKLIITCHEGFKIRYPDLHNMVSLCRDDGTWNN-LPIC--QGCLRPL 184
Query: 476 AVSNASVTVN----GHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVN-CG 530
A SN V ++ G++ SY C G L GS + C WS PP C + C
Sbjct: 185 ASSNGYVNISELQTSFPVGTVISYRCFPGFKLDGSAYLECLQNLIWSSSPPRCLALEVCP 244
Query: 531 -TPTIHKGSFVLINGTT---TYGSIAQFTCEPDYWLNGAEELVCNRDGKW--SYDI 580
P + G FV +G++ +F C+P Y L + + + G+W SY +
Sbjct: 245 LPPMVSHGDFVCHPRPCERYNHGTVVEFYCDPGYSLTSDYKYITCQYGEWFPSYQV 300
Score = 69.3 bits (162), Expect = 7e-11
Identities = 62/247 (25%), Positives = 98/247 (39%), Gaps = 26/247 (10%)
Query: 471 CPDPPAVSNASVTVNGHK--AGSLASYTCENGHILSGSTSVTCT--LGGAWSGVPPS--- 523
C DP N T +G GS+A + C++G L G+T C G +P
Sbjct: 57 CADPGIPENGFRTPSGGVFFEGSVARFHCQDGFKLKGATKRLCLKHFNGTLGWIPSDNSI 116
Query: 524 CKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAE----ELVCNRDGKWSYD 579
C +C P I + N T +G TC + + + +C DG W+ +
Sbjct: 117 CVQEDCRIPQIEDAE--IHNKTYRHGEKLIITCHEGFKIRYPDLHNMVSLCRDDGTWN-N 173
Query: 580 IPSCELTSCPEPEVPSGGYMEAFD----YYVHSTINFHCEAGHKLIGEPNLVCQQDGEWS 635
+P C+ C P S GY+ + + V + I++ C G KL G L C Q+ WS
Sbjct: 174 LPICQ--GCLRPLASSNGYVNISELQTSFPVGTVISYRCFPGFKLDGSAYLECLQNLIWS 231
Query: 636 GDSPTCEYID-CGKLPTLPYGTM----ELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTE 690
P C ++ C P + +G H G+V+++ C Y L + +
Sbjct: 232 SSPPRCLALEVCPLPPMVSHGDFVCHPRPCERYNH-GTVVEFYCDPGYSLTSDYKYITCQ 290
Query: 691 EFQWSDS 697
+W S
Sbjct: 291 YGEWFPS 297
Score = 68.9 bits (161), Expect = 9e-11
Identities = 58/210 (27%), Positives = 87/210 (41%), Gaps = 21/210 (10%)
Query: 764 LSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVI 823
L+ C Q +G Q C +PG ENG T F G+ A + C + ++L+G
Sbjct: 38 LALCFGPAQLTGGFDDLQV--CADPGIPENGFRTPSGGVFFEGSVARFHCQDGFKLKGAT 95
Query: 824 RRMCQE--NGTWSLEP---PICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERG 878
+R+C + NGT P IC + C P QI+ + T G + C G
Sbjct: 96 KRLCLKHFNGTLGWIPSDNSICVQEDCRIP--QIEDAE---IHNKTYRHGEKLIITCHEG 150
Query: 879 YNLK----GHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLF--GSSVE 932
+ ++ + C G WN +P+C C P NG + IS T F G+ +
Sbjct: 151 FKIRYPDLHNMVSLCRDDGTWN-NLPIC--QGCLRPLASSNGYVNISELQTSFPVGTVIS 207
Query: 933 YYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
Y C ++ G +CL + WS P C
Sbjct: 208 YRCFPGFKLDGSAYLECLQNLIWSSSPPRC 237
Score = 65.7 bits (153), Expect = 9e-10
Identities = 56/265 (21%), Positives = 107/265 (40%), Gaps = 38/265 (14%)
Query: 584 ELTSCPEPEVPSGGYMEAFD--YYVHSTINFHCEAGHKLIGEPNLVCQQD-----GEWSG 636
+L C +P +P G+ ++ S FHC+ G KL G +C + G
Sbjct: 53 DLQVCADPGIPENGFRTPSGGVFFEGSVARFHCQDGFKLKGATKRLCLKHFNGTLGWIPS 112
Query: 637 DSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGP----VRRTCTEEF 692
D+ C DC ++P + E+ N T G + +C +++ P + C ++
Sbjct: 113 DNSICVQEDC-RIPQIE--DAEIHNKTYRHGEKLIITCHEGFKIRYPDLHNMVSLCRDDG 169
Query: 693 QWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYR 752
W++ P C+ C P+ + V+++ ++ ++ +G ++ YR
Sbjct: 170 TWNNL-PICQG--CLRPLASSNGYVNIS-----------------ELQTSFPVGTVISYR 209
Query: 753 CEKGYKVIGESLSTCEDNGQWSGTTPTCQYVD-CGNPGRIENGKVTL---PSNATFYGAT 808
C G+K+ G + C N WS + P C ++ C P + +G P +G
Sbjct: 210 CFPGFKLDGSAYLECLQNLIWSSSPPRCLALEVCPLPPMVSHGDFVCHPRPCERYNHGTV 269
Query: 809 AFYQCDENWELEGVIRRMCQENGTW 833
+ CD + L + + + G W
Sbjct: 270 VEFYCDPGYSLTSDYKYITCQYGEW 294
Score = 64.1 bits (149), Expect = 3e-09
Identities = 54/231 (23%), Positives = 97/231 (41%), Gaps = 23/231 (9%)
Query: 740 GNTYRIGALVKYRCEKGYKVIGESLSTC--EDNGQ--W-SGTTPTCQYVDCGNPGRIENG 794
G + G++ ++ C+ G+K+ G + C NG W C DC P +IE+
Sbjct: 72 GGVFFEGSVARFHCQDGFKLKGATKRLCLKHFNGTLGWIPSDNSICVQEDCRIP-QIEDA 130
Query: 795 KVTLPSNATF-YGATAFYQCDENW-----ELEGVIRRMCQENGTWSLEPPICKEITCPDP 848
++ N T+ +G C E + +L ++ +C+++GTW+ PIC+ C P
Sbjct: 131 EI---HNKTYRHGEKLIITCHEGFKIRYPDLHNMVS-LCRDDGTWN-NLPICQG--CLRP 183
Query: 849 SAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPID-C 907
A + + ++ +G Y+C G+ L G C+ W+ + P C+ ++ C
Sbjct: 184 LASSNGYVNISELQTSFPVGTVISYRCFPGFKLDGSAYLECLQNLIWSSSPPRCLALEVC 243
Query: 908 RSPGNIENGKIVISNGST---LFGSSVEYYCLSQYQRVGPFLRKCLDDGRW 955
P + +G V G+ VE+YC Y + G W
Sbjct: 244 PLPPMVSHGDFVCHPRPCERYNHGTVVEFYCDPGYSLTSDYKYITCQYGEW 294
Score = 61.3 bits (142), Expect = 2e-08
Identities = 64/258 (24%), Positives = 103/258 (39%), Gaps = 33/258 (12%)
Query: 529 CGTPTIHKGSFVLINGTTTY-GSIAQFTCEPDYWLNGAEELVCNRDGKWSYD-IPS---- 582
C P I + F +G + GS+A+F C+ + L GA + +C + + IPS
Sbjct: 57 CADPGIPENGFRTPSGGVFFEGSVARFHCQDGFKLKGATKRLCLKHFNGTLGWIPSDNSI 116
Query: 583 CELTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNL-----VCQQDGEWSGD 637
C C P++ Y + C G K I P+L +C+ DG W+ +
Sbjct: 117 CVQEDCRIPQIEDAEIHNK-TYRHGEKLIITCHEGFK-IRYPDLHNMVSLCRDDGTWN-N 173
Query: 638 SPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDS 697
P C+ + Y + L + +G+VI Y C ++L G C + WS S
Sbjct: 174 LPICQGCLRPLASSNGYVNISELQTSFPVGTVISYRCFPGFKLDGSAYLECLQNLIWSSS 233
Query: 698 SPRCEEIR-CSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKG 756
PRC + C P + SHG + Y G +V++ C+ G
Sbjct: 234 PPRCLALEVCPLPPMV------------SHGDFVCHPRP----CERYNHGTVVEFYCDPG 277
Query: 757 YKVIGE-SLSTCEDNGQW 773
Y + + TC+ G+W
Sbjct: 278 YSLTSDYKYITCQ-YGEW 294
Score = 44.4 bits (100), Expect = 0.002
Identities = 31/119 (26%), Positives = 47/119 (39%), Gaps = 4/119 (3%)
Query: 345 ICQYLPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPP 404
ICQ S + +N + L + VG+ I Y+C G L G C ++ WS +PP
Sbjct: 176 ICQGCLRPLASSNGYVNISELQTSFPVGTVISYRCFPGFKLDGSAYLECLQNLIWSSSPP 235
Query: 405 SCKYVNCGGLTP-IEDGDVALID---NRTTHGARALYSCRENFTLVGNPERTCGDEGIW 459
C + L P + GD R HG + C ++L + + G W
Sbjct: 236 RCLALEVCPLPPMVSHGDFVCHPRPCERYNHGTVVEFYCDPGYSLTSDYKYITCQYGEW 294
Score = 36.7 bits (81), Expect = 0.45
Identities = 18/58 (31%), Positives = 26/58 (44%), Gaps = 1/58 (1%)
Query: 2 CGHPAVPPNARVSIPN-EENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C P N V+I + + GT+ Y C G++L G+ EC W+ PP C
Sbjct: 180 CLRPLASSNGYVNISELQTSFPVGTVISYRCFPGFKLDGSAYLECLQNLIWSSSPPRC 237
Score = 33.9 bits (74), Expect = 3.2
Identities = 16/52 (30%), Positives = 26/52 (50%), Gaps = 1/52 (1%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTL 53
C P +P N P+ G++A + C +G++L GA +R C + TL
Sbjct: 57 CADPGIPENG-FRTPSGGVFFEGSVARFHCQDGFKLKGATKRLCLKHFNGTL 107
>AL359733-2|CAH73991.1| 490|Homo sapiens sushi domain containing 4
protein.
Length = 490
Score = 73.7 bits (173), Expect = 3e-12
Identities = 67/236 (28%), Positives = 99/236 (41%), Gaps = 28/236 (11%)
Query: 366 GNDYDVGSRIVYKCPEGHMLLGDKSRHCKK--DGFWSGAPPS---CKYVNCGGLTPIEDG 420
G + GS + C +G L G R C K +G P C +C + IED
Sbjct: 72 GGVFFEGSVARFHCQDGFKLKGATKRLCLKHFNGTLGWIPSDNSICVQEDCR-IPQIEDA 130
Query: 421 DVALIDNRT-THGARALYSCRENFTL----VGNPERTCGDEGIWDGEAPRCLFDWCPDPP 475
+ I N+T HG + + +C E F + + N C D+G W+ P C C P
Sbjct: 131 E---IHNKTYRHGEKLIITCHEGFKIRYPDLHNMVSLCRDDGTWNN-LPIC--QGCLRPL 184
Query: 476 AVSNASVTVN----GHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVN-CG 530
A SN V ++ G++ SY C G L GS + C WS PP C + C
Sbjct: 185 ASSNGYVNISELQTSFPVGTVISYRCFPGFKLDGSAYLECLQNLIWSSSPPRCLALEVCP 244
Query: 531 -TPTIHKGSFVLINGTT---TYGSIAQFTCEPDYWLNGAEELVCNRDGKW--SYDI 580
P + G FV +G++ +F C+P Y L + + + G+W SY +
Sbjct: 245 LPPMVSHGDFVCHPRPCERYNHGTVVEFYCDPGYSLTSDYKYITCQYGEWFPSYQV 300
Score = 69.3 bits (162), Expect = 7e-11
Identities = 62/247 (25%), Positives = 98/247 (39%), Gaps = 26/247 (10%)
Query: 471 CPDPPAVSNASVTVNGHK--AGSLASYTCENGHILSGSTSVTCT--LGGAWSGVPPS--- 523
C DP N T +G GS+A + C++G L G+T C G +P
Sbjct: 57 CADPGIPENGFRTPSGGVFFEGSVARFHCQDGFKLKGATKRLCLKHFNGTLGWIPSDNSI 116
Query: 524 CKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAE----ELVCNRDGKWSYD 579
C +C P I + N T +G TC + + + +C DG W+ +
Sbjct: 117 CVQEDCRIPQIEDAE--IHNKTYRHGEKLIITCHEGFKIRYPDLHNMVSLCRDDGTWN-N 173
Query: 580 IPSCELTSCPEPEVPSGGYMEAFD----YYVHSTINFHCEAGHKLIGEPNLVCQQDGEWS 635
+P C+ C P S GY+ + + V + I++ C G KL G L C Q+ WS
Sbjct: 174 LPICQ--GCLRPLASSNGYVNISELQTSFPVGTVISYRCFPGFKLDGSAYLECLQNLIWS 231
Query: 636 GDSPTCEYID-CGKLPTLPYGTM----ELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTE 690
P C ++ C P + +G H G+V+++ C Y L + +
Sbjct: 232 SSPPRCLALEVCPLPPMVSHGDFVCHPRPCERYNH-GTVVEFYCDPGYSLTSDYKYITCQ 290
Query: 691 EFQWSDS 697
+W S
Sbjct: 291 YGEWFPS 297
Score = 68.9 bits (161), Expect = 9e-11
Identities = 58/210 (27%), Positives = 87/210 (41%), Gaps = 21/210 (10%)
Query: 764 LSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVI 823
L+ C Q +G Q C +PG ENG T F G+ A + C + ++L+G
Sbjct: 38 LALCFGPAQLTGGFDDLQV--CADPGIPENGFRTPSGGVFFEGSVARFHCQDGFKLKGAT 95
Query: 824 RRMCQE--NGTWSLEP---PICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERG 878
+R+C + NGT P IC + C P QI+ + T G + C G
Sbjct: 96 KRLCLKHFNGTLGWIPSDNSICVQEDCRIP--QIEDAE---IHNKTYRHGEKLIITCHEG 150
Query: 879 YNLK----GHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLF--GSSVE 932
+ ++ + C G WN +P+C C P NG + IS T F G+ +
Sbjct: 151 FKIRYPDLHNMVSLCRDDGTWN-NLPIC--QGCLRPLASSNGYVNISELQTSFPVGTVIS 207
Query: 933 YYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
Y C ++ G +CL + WS P C
Sbjct: 208 YRCFPGFKLDGSAYLECLQNLIWSSSPPRC 237
Score = 65.7 bits (153), Expect = 9e-10
Identities = 56/265 (21%), Positives = 107/265 (40%), Gaps = 38/265 (14%)
Query: 584 ELTSCPEPEVPSGGYMEAFD--YYVHSTINFHCEAGHKLIGEPNLVCQQD-----GEWSG 636
+L C +P +P G+ ++ S FHC+ G KL G +C + G
Sbjct: 53 DLQVCADPGIPENGFRTPSGGVFFEGSVARFHCQDGFKLKGATKRLCLKHFNGTLGWIPS 112
Query: 637 DSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGP----VRRTCTEEF 692
D+ C DC ++P + E+ N T G + +C +++ P + C ++
Sbjct: 113 DNSICVQEDC-RIPQIE--DAEIHNKTYRHGEKLIITCHEGFKIRYPDLHNMVSLCRDDG 169
Query: 693 QWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYR 752
W++ P C+ C P+ + V+++ ++ ++ +G ++ YR
Sbjct: 170 TWNNL-PICQG--CLRPLASSNGYVNIS-----------------ELQTSFPVGTVISYR 209
Query: 753 CEKGYKVIGESLSTCEDNGQWSGTTPTCQYVD-CGNPGRIENGKVTL---PSNATFYGAT 808
C G+K+ G + C N WS + P C ++ C P + +G P +G
Sbjct: 210 CFPGFKLDGSAYLECLQNLIWSSSPPRCLALEVCPLPPMVSHGDFVCHPRPCERYNHGTV 269
Query: 809 AFYQCDENWELEGVIRRMCQENGTW 833
+ CD + L + + + G W
Sbjct: 270 VEFYCDPGYSLTSDYKYITCQYGEW 294
Score = 64.1 bits (149), Expect = 3e-09
Identities = 54/231 (23%), Positives = 97/231 (41%), Gaps = 23/231 (9%)
Query: 740 GNTYRIGALVKYRCEKGYKVIGESLSTC--EDNGQ--W-SGTTPTCQYVDCGNPGRIENG 794
G + G++ ++ C+ G+K+ G + C NG W C DC P +IE+
Sbjct: 72 GGVFFEGSVARFHCQDGFKLKGATKRLCLKHFNGTLGWIPSDNSICVQEDCRIP-QIEDA 130
Query: 795 KVTLPSNATF-YGATAFYQCDENW-----ELEGVIRRMCQENGTWSLEPPICKEITCPDP 848
++ N T+ +G C E + +L ++ +C+++GTW+ PIC+ C P
Sbjct: 131 EI---HNKTYRHGEKLIITCHEGFKIRYPDLHNMVS-LCRDDGTWN-NLPICQG--CLRP 183
Query: 849 SAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPID-C 907
A + + ++ +G Y+C G+ L G C+ W+ + P C+ ++ C
Sbjct: 184 LASSNGYVNISELQTSFPVGTVISYRCFPGFKLDGSAYLECLQNLIWSSSPPRCLALEVC 243
Query: 908 RSPGNIENGKIVISNGST---LFGSSVEYYCLSQYQRVGPFLRKCLDDGRW 955
P + +G V G+ VE+YC Y + G W
Sbjct: 244 PLPPMVSHGDFVCHPRPCERYNHGTVVEFYCDPGYSLTSDYKYITCQYGEW 294
Score = 61.3 bits (142), Expect = 2e-08
Identities = 64/258 (24%), Positives = 103/258 (39%), Gaps = 33/258 (12%)
Query: 529 CGTPTIHKGSFVLINGTTTY-GSIAQFTCEPDYWLNGAEELVCNRDGKWSYD-IPS---- 582
C P I + F +G + GS+A+F C+ + L GA + +C + + IPS
Sbjct: 57 CADPGIPENGFRTPSGGVFFEGSVARFHCQDGFKLKGATKRLCLKHFNGTLGWIPSDNSI 116
Query: 583 CELTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNL-----VCQQDGEWSGD 637
C C P++ Y + C G K I P+L +C+ DG W+ +
Sbjct: 117 CVQEDCRIPQIEDAEIHNK-TYRHGEKLIITCHEGFK-IRYPDLHNMVSLCRDDGTWN-N 173
Query: 638 SPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDS 697
P C+ + Y + L + +G+VI Y C ++L G C + WS S
Sbjct: 174 LPICQGCLRPLASSNGYVNISELQTSFPVGTVISYRCFPGFKLDGSAYLECLQNLIWSSS 233
Query: 698 SPRCEEIR-CSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKG 756
PRC + C P + SHG + Y G +V++ C+ G
Sbjct: 234 PPRCLALEVCPLPPMV------------SHGDFVCHPRP----CERYNHGTVVEFYCDPG 277
Query: 757 YKVIGE-SLSTCEDNGQW 773
Y + + TC+ G+W
Sbjct: 278 YSLTSDYKYITCQ-YGEW 294
Score = 44.4 bits (100), Expect = 0.002
Identities = 31/119 (26%), Positives = 47/119 (39%), Gaps = 4/119 (3%)
Query: 345 ICQYLPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPP 404
ICQ S + +N + L + VG+ I Y+C G L G C ++ WS +PP
Sbjct: 176 ICQGCLRPLASSNGYVNISELQTSFPVGTVISYRCFPGFKLDGSAYLECLQNLIWSSSPP 235
Query: 405 SCKYVNCGGLTP-IEDGDVALID---NRTTHGARALYSCRENFTLVGNPERTCGDEGIW 459
C + L P + GD R HG + C ++L + + G W
Sbjct: 236 RCLALEVCPLPPMVSHGDFVCHPRPCERYNHGTVVEFYCDPGYSLTSDYKYITCQYGEW 294
Score = 36.7 bits (81), Expect = 0.45
Identities = 18/58 (31%), Positives = 26/58 (44%), Gaps = 1/58 (1%)
Query: 2 CGHPAVPPNARVSIPN-EENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C P N V+I + + GT+ Y C G++L G+ EC W+ PP C
Sbjct: 180 CLRPLASSNGYVNISELQTSFPVGTVISYRCFPGFKLDGSAYLECLQNLIWSSSPPRC 237
Score = 33.9 bits (74), Expect = 3.2
Identities = 16/52 (30%), Positives = 26/52 (50%), Gaps = 1/52 (1%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTL 53
C P +P N P+ G++A + C +G++L GA +R C + TL
Sbjct: 57 CADPGIPENG-FRTPSGGVFFEGSVARFHCQDGFKLKGATKRLCLKHFNGTL 107
>AY367062-1|AAQ67702.1| 138|Homo sapiens E-selectin protein.
Length = 138
Score = 72.5 bits (170), Expect = 7e-12
Identities = 36/100 (36%), Positives = 47/100 (47%), Gaps = 1/100 (1%)
Query: 544 GTTTYGSIAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCELTSCPEPEVPSGGYMEAFD 603
G TY S F+CE + L G+ +L C G+W+ ++PSC++ C VP M
Sbjct: 13 GEFTYKSSCAFSCEEGFELYGSTQLECTSQGQWTEEVPSCQVVKCSSLAVPGKINMSCSG 72
Query: 604 YYVHSTI-NFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCE 642
V T+ F C G L G C G WSG PTCE
Sbjct: 73 EPVFGTVCKFACPEGWTLNGSAARTCGATGHWSGLLPTCE 112
Score = 72.5 bits (170), Expect = 7e-12
Identities = 31/94 (32%), Positives = 49/94 (52%)
Query: 491 SLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGTPTIHKGSFVLINGTTTYGS 550
S +++CE G L GST + CT G W+ PSC+ V C + + + +G +G+
Sbjct: 19 SSCAFSCEEGFELYGSTQLECTSQGQWTEEVPSCQVVKCSSLAVPGKINMSCSGEPVFGT 78
Query: 551 IAQFTCEPDYWLNGAEELVCNRDGKWSYDIPSCE 584
+ +F C + LNG+ C G WS +P+CE
Sbjct: 79 VCKFACPEGWTLNGSAARTCGATGHWSGLLPTCE 112
Score = 66.5 bits (155), Expect = 5e-10
Identities = 35/119 (29%), Positives = 56/119 (47%), Gaps = 2/119 (1%)
Query: 603 DYYVHSTINFHCEAGHKLIGEPNLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNG 662
++ S+ F CE G +L G L C G+W+ + P+C+ + C L +P +G
Sbjct: 14 EFTYKSSCAFSCEEGFELYGSTQLECTSQGQWTEEVPSCQVVKCSSL-AVPGKINMSCSG 72
Query: 663 TTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSD-PIVAEKSIVSVT 720
G+V +++C + L G RTC WS P CE S+ P+VA S ++
Sbjct: 73 EPVFGTVCKFACPEGWTLNGSAARTCGATGHWSGLLPTCEAPTESNIPLVAGLSAAGLS 131
Score = 65.3 bits (152), Expect = 1e-09
Identities = 29/97 (29%), Positives = 47/97 (48%), Gaps = 1/97 (1%)
Query: 430 THGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTVNGHKA 489
T+ + +SC E F L G+ + C +G W E P C C +++ +G
Sbjct: 16 TYKSSCAFSCEEGFELYGSTQLECTSQGQWTEEVPSCQVVKCSSLAVPGKINMSCSGEPV 75
Query: 490 -GSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCK 525
G++ + C G L+GS + TC G WSG+ P+C+
Sbjct: 76 FGTVCKFACPEGWTLNGSAARTCGATGHWSGLLPTCE 112
Score = 64.1 bits (149), Expect = 3e-09
Identities = 30/95 (31%), Positives = 44/95 (46%), Gaps = 3/95 (3%)
Query: 751 YRCEKGYKVIGESLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLP-SNATFYGATA 809
+ CE+G+++ G + C GQW+ P+CQ V C + GK+ + S +G
Sbjct: 23 FSCEEGFELYGSTQLECTSQGQWTEEVPSCQVVKCSS--LAVPGKINMSCSGEPVFGTVC 80
Query: 810 FYQCDENWELEGVIRRMCQENGTWSLEPPICKEIT 844
+ C E W L G R C G WS P C+ T
Sbjct: 81 KFACPEGWTLNGSAARTCGATGHWSGLLPTCEAPT 115
Score = 63.3 bits (147), Expect = 5e-09
Identities = 34/99 (34%), Positives = 47/99 (47%), Gaps = 3/99 (3%)
Query: 873 YQCERGYNLKGHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVIS-NGSTLFGSSV 931
+ CE G+ L G C S+GQW VP C + C S GKI +S +G +FG+
Sbjct: 23 FSCEEGFELYGSTQLECTSQGQWTEEVPSCQVVKCSSLA--VPGKINMSCSGEPVFGTVC 80
Query: 932 EYYCLSQYQRVGPFLRKCLDDGRWSGEEPSCELATNEAV 970
++ C + G R C G WSG P+CE T +
Sbjct: 81 KFACPEGWTLNGSAARTCGATGHWSGLLPTCEAPTESNI 119
Score = 61.7 bits (143), Expect = 1e-08
Identities = 31/100 (31%), Positives = 42/100 (42%), Gaps = 3/100 (3%)
Query: 368 DYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCKYVNCGGLTPIEDGDVAL-ID 426
++ S + C EG L G C G W+ PSC+ V C L G + +
Sbjct: 14 EFTYKSSCAFSCEEGFELYGSTQLECTSQGQWTEEVPSCQVVKCSSLA--VPGKINMSCS 71
Query: 427 NRTTHGARALYSCRENFTLVGNPERTCGDEGIWDGEAPRC 466
G ++C E +TL G+ RTCG G W G P C
Sbjct: 72 GEPVFGTVCKFACPEGWTLNGSAARTCGATGHWSGLLPTC 111
Score = 60.5 bits (140), Expect = 3e-08
Identities = 28/98 (28%), Positives = 45/98 (45%), Gaps = 3/98 (3%)
Query: 805 YGATAFYQCDENWELEGVIRRMCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTST 864
Y ++ + C+E +EL G + C G W+ E P C+ + C S+ G + +
Sbjct: 17 YKSSCAFSCEEGFELYGSTQLECTSQGQWTEEVPSCQVVKC---SSLAVPGKINMSCSGE 73
Query: 865 LSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVC 902
G + C G+ L G RTC + G W+G +P C
Sbjct: 74 PVFGTVCKFACPEGWTLNGSAARTCGATGHWSGLLPTC 111
Score = 56.8 bits (131), Expect = 4e-07
Identities = 30/110 (27%), Positives = 48/110 (43%), Gaps = 20/110 (18%)
Query: 672 YSCTTNYRLVGPVRRTCTEEFQWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLI 731
+SC + L G + CT + QW++ P C+ ++CS V K +S +G
Sbjct: 23 FSCEEGFELYGSTQLECTSQGQWTEEVPSCQVVKCSSLAVPGKINMSCSGEP-------- 74
Query: 732 RTSDNRDVGNTYRIGALVKYRCEKGYKVIGESLSTCEDNGQWSGTTPTCQ 781
G + K+ C +G+ + G + TC G WSG PTC+
Sbjct: 75 ------------VFGTVCKFACPEGWTLNGSAARTCGATGHWSGLLPTCE 112
Score = 45.6 bits (103), Expect = 0.001
Identities = 16/30 (53%), Positives = 22/30 (73%)
Query: 29 YECDEGYELFGARQRECTLRGDWTLEPPFC 58
+ C+EG+EL+G+ Q ECT +G WT E P C
Sbjct: 23 FSCEEGFELYGSTQLECTSQGQWTEEVPSC 52
Score = 38.3 bits (85), Expect = 0.15
Identities = 20/58 (34%), Positives = 27/58 (46%), Gaps = 2/58 (3%)
Query: 1 RCGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
+C AVP +S E V GT+ + C EG+ L G+ R C G W+ P C
Sbjct: 56 KCSSLAVPGKINMSCSGEP--VFGTVCKFACPEGWTLNGSAARTCGATGHWSGLLPTC 111
Score = 37.1 bits (82), Expect = 0.34
Identities = 15/36 (41%), Positives = 20/36 (55%)
Query: 372 GSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPPSCK 407
G+ + CPEG L G +R C G WSG P+C+
Sbjct: 77 GTVCKFACPEGWTLNGSAARTCGATGHWSGLLPTCE 112
>AY358495-1|AAQ88859.1| 490|Homo sapiens YHGM196 protein.
Length = 490
Score = 72.5 bits (170), Expect = 7e-12
Identities = 66/238 (27%), Positives = 98/238 (41%), Gaps = 30/238 (12%)
Query: 366 GNDYDVGSRIVYKCPEGHMLLGDKSRHCKK--DGFWSGAPPS---CKYVNCGGLTPIEDG 420
G + GS + C +G L G R C K +G P C +C + IED
Sbjct: 72 GGVFFEGSVARFHCQDGFKLKGATKRLCLKHFNGTLGWIPSDNSICVQEDCR-IPQIEDA 130
Query: 421 DVALIDNRT-THGARALYSCRENFTL----VGNPERTCGDEGIWDGEAPRCLFDWCPDPP 475
+ I N+T HG + + +C E F + + N C D+G W+ P C C P
Sbjct: 131 E---IHNKTYRHGEKLIITCHEGFKIRYPDLHNMVSLCRDDGTWNN-LPIC--QGCLRPL 184
Query: 476 AVSNASVTVN----GHKAGSLASYTCENGHILSGSTSVTCTLGGAWSGVPPSCKYVNCGT 531
A SN V ++ G++ SY C G L GS + C WS PP C +
Sbjct: 185 ASSNGYVNISELQTSFPVGTVISYRCFPGFKLDGSAYLECLQNLIWSSSPPRCLALEAQV 244
Query: 532 ----PTIHKGSFVLINGTT---TYGSIAQFTCEPDYWLNGAEELVCNRDGKW--SYDI 580
P + G FV +G++ +F C+P Y L + + + G+W SY +
Sbjct: 245 CPLPPMVSHGDFVCHPRPCERYNHGTVVEFYCDPGYSLTSDYKYITCQYGEWFPSYQV 302
Score = 68.9 bits (161), Expect = 9e-11
Identities = 58/210 (27%), Positives = 87/210 (41%), Gaps = 21/210 (10%)
Query: 764 LSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLPSNATFYGATAFYQCDENWELEGVI 823
L+ C Q +G Q C +PG ENG T F G+ A + C + ++L+G
Sbjct: 38 LALCFGPAQLTGGFDDLQV--CADPGIPENGFRTPSGGVFFEGSVARFHCQDGFKLKGAT 95
Query: 824 RRMCQE--NGTWSLEP---PICKEITCPDPSAQIKAGSGLLVVTSTLSIGGEAHYQCERG 878
+R+C + NGT P IC + C P QI+ + T G + C G
Sbjct: 96 KRLCLKHFNGTLGWIPSDNSICVQEDCRIP--QIEDAE---IHNKTYRHGEKLIITCHEG 150
Query: 879 YNLK----GHQTRTCISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGSTLF--GSSVE 932
+ ++ + C G WN +P+C C P NG + IS T F G+ +
Sbjct: 151 FKIRYPDLHNMVSLCRDDGTWN-NLPIC--QGCLRPLASSNGYVNISELQTSFPVGTVIS 207
Query: 933 YYCLSQYQRVGPFLRKCLDDGRWSGEEPSC 962
Y C ++ G +CL + WS P C
Sbjct: 208 YRCFPGFKLDGSAYLECLQNLIWSSSPPRC 237
Score = 67.7 bits (158), Expect = 2e-10
Identities = 62/249 (24%), Positives = 98/249 (39%), Gaps = 28/249 (11%)
Query: 471 CPDPPAVSNASVTVNGHK--AGSLASYTCENGHILSGSTSVTCT--LGGAWSGVPPS--- 523
C DP N T +G GS+A + C++G L G+T C G +P
Sbjct: 57 CADPGIPENGFRTPSGGVFFEGSVARFHCQDGFKLKGATKRLCLKHFNGTLGWIPSDNSI 116
Query: 524 CKYVNCGTPTIHKGSFVLINGTTTYGSIAQFTCEPDYWLNGAE----ELVCNRDGKWSYD 579
C +C P I + N T +G TC + + + +C DG W+ +
Sbjct: 117 CVQEDCRIPQIEDAE--IHNKTYRHGEKLIITCHEGFKIRYPDLHNMVSLCRDDGTWN-N 173
Query: 580 IPSCELTSCPEPEVPSGGYMEAFD----YYVHSTINFHCEAGHKLIGEPNLVCQQDGEWS 635
+P C+ C P S GY+ + + V + I++ C G KL G L C Q+ WS
Sbjct: 174 LPICQ--GCLRPLASSNGYVNISELQTSFPVGTVISYRCFPGFKLDGSAYLECLQNLIWS 231
Query: 636 GDSPTCEYID---CGKLPTLPYGTM----ELLNGTTHLGSVIQYSCTTNYRLVGPVRRTC 688
P C ++ C P + +G H G+V+++ C Y L +
Sbjct: 232 SSPPRCLALEAQVCPLPPMVSHGDFVCHPRPCERYNH-GTVVEFYCDPGYSLTSDYKYIT 290
Query: 689 TEEFQWSDS 697
+ +W S
Sbjct: 291 CQYGEWFPS 299
Score = 64.1 bits (149), Expect = 3e-09
Identities = 56/267 (20%), Positives = 107/267 (40%), Gaps = 40/267 (14%)
Query: 584 ELTSCPEPEVPSGGYMEAFD--YYVHSTINFHCEAGHKLIGEPNLVCQQD-----GEWSG 636
+L C +P +P G+ ++ S FHC+ G KL G +C + G
Sbjct: 53 DLQVCADPGIPENGFRTPSGGVFFEGSVARFHCQDGFKLKGATKRLCLKHFNGTLGWIPS 112
Query: 637 DSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGP----VRRTCTEEF 692
D+ C DC ++P + E+ N T G + +C +++ P + C ++
Sbjct: 113 DNSICVQEDC-RIPQIE--DAEIHNKTYRHGEKLIITCHEGFKIRYPDLHNMVSLCRDDG 169
Query: 693 QWSDSSPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYR 752
W++ P C+ C P+ + V+++ ++ ++ +G ++ YR
Sbjct: 170 TWNNL-PICQG--CLRPLASSNGYVNIS-----------------ELQTSFPVGTVISYR 209
Query: 753 CEKGYKVIGESLSTCEDNGQWSGTTPTCQYVD---CGNPGRIENGKVTL---PSNATFYG 806
C G+K+ G + C N WS + P C ++ C P + +G P +G
Sbjct: 210 CFPGFKLDGSAYLECLQNLIWSSSPPRCLALEAQVCPLPPMVSHGDFVCHPRPCERYNHG 269
Query: 807 ATAFYQCDENWELEGVIRRMCQENGTW 833
+ CD + L + + + G W
Sbjct: 270 TVVEFYCDPGYSLTSDYKYITCQYGEW 296
Score = 62.5 bits (145), Expect = 8e-09
Identities = 54/233 (23%), Positives = 97/233 (41%), Gaps = 25/233 (10%)
Query: 740 GNTYRIGALVKYRCEKGYKVIGESLSTC--EDNGQ--W-SGTTPTCQYVDCGNPGRIENG 794
G + G++ ++ C+ G+K+ G + C NG W C DC P +IE+
Sbjct: 72 GGVFFEGSVARFHCQDGFKLKGATKRLCLKHFNGTLGWIPSDNSICVQEDCRIP-QIEDA 130
Query: 795 KVTLPSNATF-YGATAFYQCDENW-----ELEGVIRRMCQENGTWSLEPPICKEITCPDP 848
++ N T+ +G C E + +L ++ +C+++GTW+ PIC+ C P
Sbjct: 131 EI---HNKTYRHGEKLIITCHEGFKIRYPDLHNMVS-LCRDDGTWN-NLPICQG--CLRP 183
Query: 849 SAQIKAGSGLLVVTSTLSIGGEAHYQCERGYNLKGHQTRTCISKGQWNGTVPVCIPID-- 906
A + + ++ +G Y+C G+ L G C+ W+ + P C+ ++
Sbjct: 184 LASSNGYVNISELQTSFPVGTVISYRCFPGFKLDGSAYLECLQNLIWSSSPPRCLALEAQ 243
Query: 907 -CRSPGNIENGKIVISNGST---LFGSSVEYYCLSQYQRVGPFLRKCLDDGRW 955
C P + +G V G+ VE+YC Y + G W
Sbjct: 244 VCPLPPMVSHGDFVCHPRPCERYNHGTVVEFYCDPGYSLTSDYKYITCQYGEW 296
Score = 61.7 bits (143), Expect = 1e-08
Identities = 64/257 (24%), Positives = 104/257 (40%), Gaps = 29/257 (11%)
Query: 529 CGTPTIHKGSFVLINGTTTY-GSIAQFTCEPDYWLNGAEELVCNRDGKWSYD-IPS---- 582
C P I + F +G + GS+A+F C+ + L GA + +C + + IPS
Sbjct: 57 CADPGIPENGFRTPSGGVFFEGSVARFHCQDGFKLKGATKRLCLKHFNGTLGWIPSDNSI 116
Query: 583 CELTSCPEPEVPSGGYMEAFDYYVHSTINFHCEAGHKLIGEPNL-----VCQQDGEWSGD 637
C C P++ Y + C G K I P+L +C+ DG W+ +
Sbjct: 117 CVQEDCRIPQIEDAEIHNK-TYRHGEKLIITCHEGFK-IRYPDLHNMVSLCRDDGTWN-N 173
Query: 638 SPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDS 697
P C+ + Y + L + +G+VI Y C ++L G C + WS S
Sbjct: 174 LPICQGCLRPLASSNGYVNISELQTSFPVGTVISYRCFPGFKLDGSAYLECLQNLIWSSS 233
Query: 698 SPRCEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGY 757
PRC +A ++ V SHG + Y G +V++ C+ GY
Sbjct: 234 PPRC---------LALEAQVCPLPPMVSHGDFVCHPRP----CERYNHGTVVEFYCDPGY 280
Query: 758 KVIGE-SLSTCEDNGQW 773
+ + TC+ G+W
Sbjct: 281 SLTSDYKYITCQ-YGEW 296
Score = 39.9 bits (89), Expect = 0.049
Identities = 30/121 (24%), Positives = 46/121 (38%), Gaps = 6/121 (4%)
Query: 345 ICQYLPPTCGSPDKLLNTTILGNDYDVGSRIVYKCPEGHMLLGDKSRHCKKDGFWSGAPP 404
ICQ S + +N + L + VG+ I Y+C G L G C ++ WS +PP
Sbjct: 176 ICQGCLRPLASSNGYVNISELQTSFPVGTVISYRCFPGFKLDGSAYLECLQNLIWSSSPP 235
Query: 405 SCKYVN---CGGLTPIEDGDVALID---NRTTHGARALYSCRENFTLVGNPERTCGDEGI 458
C + C + GD R HG + C ++L + + G
Sbjct: 236 RCLALEAQVCPLPPMVSHGDFVCHPRPCERYNHGTVVEFYCDPGYSLTSDYKYITCQYGE 295
Query: 459 W 459
W
Sbjct: 296 W 296
Score = 36.7 bits (81), Expect = 0.45
Identities = 18/58 (31%), Positives = 26/58 (44%), Gaps = 1/58 (1%)
Query: 2 CGHPAVPPNARVSIPN-EENIVAGTIAVYECDEGYELFGARQRECTLRGDWTLEPPFC 58
C P N V+I + + GT+ Y C G++L G+ EC W+ PP C
Sbjct: 180 CLRPLASSNGYVNISELQTSFPVGTVISYRCFPGFKLDGSAYLECLQNLIWSSSPPRC 237
Score = 33.9 bits (74), Expect = 3.2
Identities = 16/52 (30%), Positives = 26/52 (50%), Gaps = 1/52 (1%)
Query: 2 CGHPAVPPNARVSIPNEENIVAGTIAVYECDEGYELFGARQRECTLRGDWTL 53
C P +P N P+ G++A + C +G++L GA +R C + TL
Sbjct: 57 CADPGIPENG-FRTPSGGVFFEGSVARFHCQDGFKLKGATKRLCLKHFNGTL 107
>AF026547-1|AAC80576.1| 1321|Homo sapiens neurocan protein.
Length = 1321
Score = 72.5 bits (170), Expect = 7e-12
Identities = 47/182 (25%), Positives = 82/182 (45%), Gaps = 16/182 (8%)
Query: 222 FSRNCYEFNVARGGSFDEARKQCQSHGGDLIHGFQGATSSFLTQELERRKAQLKTQLVWI 281
F +CY + A ++++A K C+ G L SF+ + WI
Sbjct: 1095 FQGHCYRY-FAHRRAWEDAEKDCRRRSGHLTSVHSPEEHSFINS--------FGHENTWI 1145
Query: 282 GAQKEPGLTSRTWQWVDGELVSKPSWGKDQPNNY-NGEQNCVVLDGGRGWLWNDVGCNLD 340
G + R +QW D + +W ++QP+N+ G ++CVV+ WNDV CN +
Sbjct: 1146 GLNDR--IVERDFQWTDNTGLQFENWRENQPDNFFAGGEDCVVMVAHESGRWNDVPCNYN 1203
Query: 341 YLHWICQYLPPTCGSPDKLLNTTILG---NDYDVGSRIVYKCPEGHMLLGDKSRHCKKDG 397
L ++C+ CG P + N +++G +V + + Y+C EG + C+ +G
Sbjct: 1204 -LPYVCKKGTVLCGPPPAVENASLIGARKAKNNVHATVRYQCNEGFAQHHVVTIRCRSNG 1262
Query: 398 FW 399
W
Sbjct: 1263 KW 1264
Score = 36.3 bits (80), Expect = 0.60
Identities = 18/57 (31%), Positives = 25/57 (43%), Gaps = 1/57 (1%)
Query: 785 CGNPGRIENGKVTLPSNA-TFYGATAFYQCDENWELEGVIRRMCQENGTWSLEPPIC 840
CG P +EN + A AT YQC+E + V+ C+ NG W +C
Sbjct: 1215 CGPPPAVENASLIGARKAKNNVHATVRYQCNEGFAQHHVVTIRCRSNGKWDRPQIVC 1271
>BC078657-1|AAH78657.1| 1627|Homo sapiens pregnancy-associated plasma
protein A, pappalysin 1 protein.
Length = 1627
Score = 71.3 bits (167), Expect = 2e-11
Identities = 68/280 (24%), Positives = 113/280 (40%), Gaps = 34/280 (12%)
Query: 701 CEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVI 760
CE+ C + + E + ++ + +DR HG + V R L+K + V
Sbjct: 1210 CEKTDCPE-LAVENAYLNCSSSDRYHGAQCTVSCRTGYVLQIRRDDELIKSQTGPSVTV- 1267
Query: 761 GESLSTCEDNGQWSGTTPTCQYVDCGNPG--RIENGKVTLPSNATFYGATAFYQCDENWE 818
TC + G+W+ C+ VDC P ++ + P TF G+ +QC +
Sbjct: 1268 -----TCTE-GKWNKQV-ACEPVDCSIPDHHQVYAASFSCPEGTTF-GSQCSFQCRHPAQ 1319
Query: 819 LEGVIRRM-CQENGTWSLEPPICKEITC----PDPSAQIKAGSGLLVVTSTLSIGGEAHY 873
L+G + C E+G WS +C E+ C P P+A ++ + +G Y
Sbjct: 1320 LKGNNSLLTCMEDGLWSFPEALC-ELMCLAPPPVPNADLQTAR---CRENKHKVGSFCKY 1375
Query: 874 QCERGYNLKGHQTRT--------CISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGST 925
+C+ GY++ G ++ C G W C+P+ C P +G +NG
Sbjct: 1376 KCKPGYHVPGSSRKSKKRAFKTQCTQDGSWQEGA--CVPVTCDPPPPKFHGLYQCTNGFQ 1433
Query: 926 LFGSSVEYYCLSQ--YQRVGPFLRKCLDDGRWSGEEPSCE 963
F S C Q +G + C DG W+G C+
Sbjct: 1434 -FNSECRIKCEDSDASQGLGSNVIHCRKDGTWNGSFHVCQ 1472
Score = 67.3 bits (157), Expect = 3e-10
Identities = 63/224 (28%), Positives = 89/224 (39%), Gaps = 26/224 (11%)
Query: 506 STSVTCTLGGAWSGVPPSCKYVNCGTPTIHK---GSFVLINGTTTYGSIAQFTCEPDYWL 562
S +VTCT G W+ +C+ V+C P H+ SF GTT +GS F C L
Sbjct: 1264 SVTVTCT-EGKWNK-QVACEPVDCSIPDHHQVYAASFSCPEGTT-FGSQCSFQCRHPAQL 1320
Query: 563 NGAEELV-CNRDGKWSYDIPSCELTSCPEPEVPSGGYMEA----FDYYVHSTINFHCEAG 617
G L+ C DG WS+ CEL P VP+ A + V S + C+ G
Sbjct: 1321 KGNNSLLTCMEDGLWSFPEALCELMCLAPPPVPNADLQTARCRENKHKVGSFCKYKCKPG 1380
Query: 618 HKLIGEP--------NLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSV 669
+ + G C QDG W C + C P +G + NG S
Sbjct: 1381 YHVPGSSRKSKKRAFKTQCTQDGSW--QEGACVPVTCDPPPPKFHGLYQCTNG-FQFNSE 1437
Query: 670 IQYSCTTNYRLVGPVRRT--CTEEFQWSDSSPRCEEI--RCSDP 709
+ C + G C ++ W+ S C+E+ +CS P
Sbjct: 1438 CRIKCEDSDASQGLGSNVIHCRKDGTWNGSFHVCQEMQGQCSVP 1481
Score = 62.9 bits (146), Expect = 6e-09
Identities = 49/173 (28%), Positives = 70/173 (40%), Gaps = 21/173 (12%)
Query: 429 TTHGARALYSCRENFTLVGNPER-TCGDEGIWDGEAPRCLFDWCPDPPAVSNASVTV--- 484
TT G++ + CR L GN TC ++G+W C C PP V NA +
Sbjct: 1304 TTFGSQCSFQCRHPAQLKGNNSLLTCMEDGLWSFPEALCEL-MCLAPPPVPNADLQTARC 1362
Query: 485 --NGHKAGSLASYTCENGHILSGST--------SVTCTLGGAWSGVPPSCKYVNCG-TPT 533
N HK GS Y C+ G+ + GS+ CT G+W +C V C P
Sbjct: 1363 RENKHKVGSFCKYKCKPGYHVPGSSRKSKKRAFKTQCTQDGSWQ--EGACVPVTCDPPPP 1420
Query: 534 IHKGSFVLINGTTTYGSIAQFTCEPDYWLN--GAEELVCNRDGKWSYDIPSCE 584
G + NG + S + CE G+ + C +DG W+ C+
Sbjct: 1421 KFHGLYQCTNG-FQFNSECRIKCEDSDASQGLGSNVIHCRKDGTWNGSFHVCQ 1472
Score = 60.1 bits (139), Expect = 4e-08
Identities = 74/317 (23%), Positives = 123/317 (38%), Gaps = 40/317 (12%)
Query: 641 CEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPR 700
CE DC +L + + + + G+ SC T Y L +RR +E S + P
Sbjct: 1210 CEKTDCPEL-AVENAYLNCSSSDRYHGAQCTVSCRTGYVL--QIRRD--DELIKSQTGPS 1264
Query: 701 ----CEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKG 756
C E + + + E S+ + H + S + G T+ G+ ++C
Sbjct: 1265 VTVTCTEGKWNKQVACEPVDCSIPDH-----HQVYAASFSCPEGTTF--GSQCSFQCRHP 1317
Query: 757 YKVIGE-SLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLP---SNATFYGATAFYQ 812
++ G SL TC ++G WS C+ + C P + N + N G+ Y+
Sbjct: 1318 AQLKGNNSLLTCMEDGLWSFPEALCELM-CLAPPPVPNADLQTARCRENKHKVGSFCKYK 1376
Query: 813 CDENWELEGVIRR--------MCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTST 864
C + + G R+ C ++G+W + C +TC P + GL T+
Sbjct: 1377 CKPGYHVPGSSRKSKKRAFKTQCTQDGSW--QEGACVPVTCDPPPPKF---HGLYQCTNG 1431
Query: 865 LSIGGEAHYQCERGYNLKGHQTRT--CISKGQWNGTVPVCIPI--DCRSPGNI-ENGKIV 919
E +CE +G + C G WNG+ VC + C P + N K+
Sbjct: 1432 FQFNSECRIKCEDSDASQGLGSNVIHCRKDGTWNGSFHVCQEMQGQCSVPNELNSNLKLQ 1491
Query: 920 ISNGSTLFGSSVEYYCL 936
+G + GS CL
Sbjct: 1492 CPDGYAI-GSECATSCL 1507
Score = 46.8 bits (106), Expect = 4e-04
Identities = 30/82 (36%), Positives = 40/82 (48%), Gaps = 6/82 (7%)
Query: 886 TRTCISKGQWNGTVPVCIPIDCRSPGN--IENGKIVISNGSTLFGSSVEYYCLSQYQRVG 943
T TC ++G+WN V C P+DC P + + G+T FGS + C Q G
Sbjct: 1266 TVTC-TEGKWNKQV-ACEPVDCSIPDHHQVYAASFSCPEGTT-FGSQCSFQCRHPAQLKG 1322
Query: 944 P-FLRKCLDDGRWSGEEPSCEL 964
L C++DG WS E CEL
Sbjct: 1323 NNSLLTCMEDGLWSFPEALCEL 1344
Score = 32.3 bits (70), Expect = 9.7
Identities = 19/62 (30%), Positives = 26/62 (41%), Gaps = 3/62 (4%)
Query: 349 LPPTCGSPD-KLLNTTILGNDYDVGSRIVYKCPEGHML--LGDKSRHCKKDGFWSGAPPS 405
+P TC P K N + S KC + LG HC+KDG W+G+
Sbjct: 1411 VPVTCDPPPPKFHGLYQCTNGFQFNSECRIKCEDSDASQGLGSNVIHCRKDGTWNGSFHV 1470
Query: 406 CK 407
C+
Sbjct: 1471 CQ 1472
>X68280-1|CAA48341.1| 1551|Homo sapiens protein ( H.sapiens PAPP-A
mRNA for pregnancy associated plasma protein-A. ).
Length = 1551
Score = 70.9 bits (166), Expect = 2e-11
Identities = 68/280 (24%), Positives = 113/280 (40%), Gaps = 34/280 (12%)
Query: 701 CEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVI 760
CE+ C + + E + ++ + +DR HG + V R L+K + V
Sbjct: 1134 CEKTDCPE-LAVENASLNCSSSDRYHGAQCTVSCRTGYVLQIRRDDELIKSQTGPSVTV- 1191
Query: 761 GESLSTCEDNGQWSGTTPTCQYVDCGNPG--RIENGKVTLPSNATFYGATAFYQCDENWE 818
TC + G+W+ C+ VDC P ++ + P TF G+ +QC +
Sbjct: 1192 -----TCTE-GKWNKQV-ACEPVDCSIPDHHQVYAASFSCPEGTTF-GSQCSFQCRHPAQ 1243
Query: 819 LEGVIRRM-CQENGTWSLEPPICKEITC----PDPSAQIKAGSGLLVVTSTLSIGGEAHY 873
L+G + C E+G WS +C E+ C P P+A ++ + +G Y
Sbjct: 1244 LKGNNSLLTCMEDGLWSFPEALC-ELMCLAPPPVPNADLQTAR---CRENKHKVGSFCKY 1299
Query: 874 QCERGYNLKGHQTRT--------CISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGST 925
+C+ GY++ G ++ C G W C+P+ C P +G +NG
Sbjct: 1300 KCKPGYHVPGSSRKSKKRAFKTQCTQDGSWQEGA--CVPVTCDPPPPKFHGLYQCTNGFQ 1357
Query: 926 LFGSSVEYYCLSQ--YQRVGPFLRKCLDDGRWSGEEPSCE 963
F S C Q +G + C DG W+G C+
Sbjct: 1358 -FNSECRIKCEDSDASQGLGSNVIHCRKDGTWNGSFHVCQ 1396
Score = 68.9 bits (161), Expect = 9e-11
Identities = 74/274 (27%), Positives = 108/274 (39%), Gaps = 42/274 (15%)
Query: 471 CPDPPAVSNASVTVNGHKA--GSLASYTCENGHILS-------------GSTSVTCTLGG 515
CP+ AV NAS+ + G+ + +C G++L S +VTCT G
Sbjct: 1139 CPEL-AVENASLNCSSSDRYHGAQCTVSCRTGYVLQIRRDDELIKSQTGPSVTVTCT-EG 1196
Query: 516 AWSGVPPSCKYVNCGTPTIHK---GSFVLINGTTTYGSIAQFTCEPDYWLNGAEELV-CN 571
W+ +C+ V+C P H+ SF GTT +GS F C L G L+ C
Sbjct: 1197 KWNK-QVACEPVDCSIPDHHQVYAASFSCPEGTT-FGSQCSFQCRHPAQLKGNNSLLTCM 1254
Query: 572 RDGKWSYDIPSCELTSCPEPEVPSGGYMEA----FDYYVHSTINFHCEAGHKLIGEP--- 624
DG WS+ CEL P VP+ A + V S + C+ G+ + G
Sbjct: 1255 EDGLWSFPEALCELMCLAPPPVPNADLQTARCRENKHKVGSFCKYKCKPGYHVPGSSRKS 1314
Query: 625 -----NLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYR 679
C QDG W C + C P +G + NG S + C +
Sbjct: 1315 KKRAFKTQCTQDGSW--QEGACVPVTCDPPPPKFHGLYQCTNG-FQFNSECRIKCEDSDA 1371
Query: 680 LVGPVRRT--CTEEFQWSDSSPRCEEI--RCSDP 709
G C ++ W+ S C+E+ +CS P
Sbjct: 1372 SQGLGSNVIHCRKDGTWNGSFHVCQEMQGQCSVP 1405
Score = 61.3 bits (142), Expect = 2e-08
Identities = 74/317 (23%), Positives = 124/317 (39%), Gaps = 40/317 (12%)
Query: 641 CEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPR 700
CE DC +L + ++ + + G+ SC T Y L +RR +E S + P
Sbjct: 1134 CEKTDCPEL-AVENASLNCSSSDRYHGAQCTVSCRTGYVL--QIRRD--DELIKSQTGPS 1188
Query: 701 ----CEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKG 756
C E + + + E S+ + H + S + G T+ G+ ++C
Sbjct: 1189 VTVTCTEGKWNKQVACEPVDCSIPDH-----HQVYAASFSCPEGTTF--GSQCSFQCRHP 1241
Query: 757 YKVIGE-SLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLP---SNATFYGATAFYQ 812
++ G SL TC ++G WS C+ + C P + N + N G+ Y+
Sbjct: 1242 AQLKGNNSLLTCMEDGLWSFPEALCELM-CLAPPPVPNADLQTARCRENKHKVGSFCKYK 1300
Query: 813 CDENWELEGVIRR--------MCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTST 864
C + + G R+ C ++G+W + C +TC P + GL T+
Sbjct: 1301 CKPGYHVPGSSRKSKKRAFKTQCTQDGSW--QEGACVPVTCDPPPPKF---HGLYQCTNG 1355
Query: 865 LSIGGEAHYQCERGYNLKGHQTRT--CISKGQWNGTVPVCIPI--DCRSPGNI-ENGKIV 919
E +CE +G + C G WNG+ VC + C P + N K+
Sbjct: 1356 FQFNSECRIKCEDSDASQGLGSNVIHCRKDGTWNGSFHVCQEMQGQCSVPNELNSNLKLQ 1415
Query: 920 ISNGSTLFGSSVEYYCL 936
+G + GS CL
Sbjct: 1416 CPDGYAI-GSECATSCL 1431
Score = 46.8 bits (106), Expect = 4e-04
Identities = 30/82 (36%), Positives = 40/82 (48%), Gaps = 6/82 (7%)
Query: 886 TRTCISKGQWNGTVPVCIPIDCRSPGN--IENGKIVISNGSTLFGSSVEYYCLSQYQRVG 943
T TC ++G+WN V C P+DC P + + G+T FGS + C Q G
Sbjct: 1190 TVTC-TEGKWNKQV-ACEPVDCSIPDHHQVYAASFSCPEGTT-FGSQCSFQCRHPAQLKG 1246
Query: 944 P-FLRKCLDDGRWSGEEPSCEL 964
L C++DG WS E CEL
Sbjct: 1247 NNSLLTCMEDGLWSFPEALCEL 1268
Score = 32.3 bits (70), Expect = 9.7
Identities = 19/62 (30%), Positives = 26/62 (41%), Gaps = 3/62 (4%)
Query: 349 LPPTCGSPD-KLLNTTILGNDYDVGSRIVYKCPEGHML--LGDKSRHCKKDGFWSGAPPS 405
+P TC P K N + S KC + LG HC+KDG W+G+
Sbjct: 1335 VPVTCDPPPPKFHGLYQCTNGFQFNSECRIKCEDSDASQGLGSNVIHCRKDGTWNGSFHV 1394
Query: 406 CK 407
C+
Sbjct: 1395 CQ 1396
>U28727-1|AAC50543.1| 1627|Homo sapiens pregnancy-associated plasma
protein-A preproform protein.
Length = 1627
Score = 70.9 bits (166), Expect = 2e-11
Identities = 68/280 (24%), Positives = 113/280 (40%), Gaps = 34/280 (12%)
Query: 701 CEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVI 760
CE+ C + + E + ++ + +DR HG + V R L+K + V
Sbjct: 1210 CEKTDCPE-LAVENASLNCSSSDRYHGAQCTVSCRTGYVLQIRRDDELIKSQTGPSVTV- 1267
Query: 761 GESLSTCEDNGQWSGTTPTCQYVDCGNPG--RIENGKVTLPSNATFYGATAFYQCDENWE 818
TC + G+W+ C+ VDC P ++ + P TF G+ +QC +
Sbjct: 1268 -----TCTE-GKWNKQV-ACEPVDCSIPDHHQVYAASFSCPEGTTF-GSQCSFQCRHPAQ 1319
Query: 819 LEGVIRRM-CQENGTWSLEPPICKEITC----PDPSAQIKAGSGLLVVTSTLSIGGEAHY 873
L+G + C E+G WS +C E+ C P P+A ++ + +G Y
Sbjct: 1320 LKGNNSLLTCMEDGLWSFPEALC-ELMCLAPPPVPNADLQTAR---CRENKHKVGSFCKY 1375
Query: 874 QCERGYNLKGHQTRT--------CISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGST 925
+C+ GY++ G ++ C G W C+P+ C P +G +NG
Sbjct: 1376 KCKPGYHVPGSSRKSKKRAFKTQCTQDGSWQEGA--CVPVTCDPPPPKFHGLYQCTNGFQ 1433
Query: 926 LFGSSVEYYCLSQ--YQRVGPFLRKCLDDGRWSGEEPSCE 963
F S C Q +G + C DG W+G C+
Sbjct: 1434 -FNSECRIKCEDSDASQGLGSNVIHCRKDGTWNGSFHVCQ 1472
Score = 68.9 bits (161), Expect = 9e-11
Identities = 74/274 (27%), Positives = 108/274 (39%), Gaps = 42/274 (15%)
Query: 471 CPDPPAVSNASVTVNGHKA--GSLASYTCENGHILS-------------GSTSVTCTLGG 515
CP+ AV NAS+ + G+ + +C G++L S +VTCT G
Sbjct: 1215 CPEL-AVENASLNCSSSDRYHGAQCTVSCRTGYVLQIRRDDELIKSQTGPSVTVTCT-EG 1272
Query: 516 AWSGVPPSCKYVNCGTPTIHK---GSFVLINGTTTYGSIAQFTCEPDYWLNGAEELV-CN 571
W+ +C+ V+C P H+ SF GTT +GS F C L G L+ C
Sbjct: 1273 KWNK-QVACEPVDCSIPDHHQVYAASFSCPEGTT-FGSQCSFQCRHPAQLKGNNSLLTCM 1330
Query: 572 RDGKWSYDIPSCELTSCPEPEVPSGGYMEA----FDYYVHSTINFHCEAGHKLIGEP--- 624
DG WS+ CEL P VP+ A + V S + C+ G+ + G
Sbjct: 1331 EDGLWSFPEALCELMCLAPPPVPNADLQTARCRENKHKVGSFCKYKCKPGYHVPGSSRKS 1390
Query: 625 -----NLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYR 679
C QDG W C + C P +G + NG S + C +
Sbjct: 1391 KKRAFKTQCTQDGSW--QEGACVPVTCDPPPPKFHGLYQCTNG-FQFNSECRIKCEDSDA 1447
Query: 680 LVGPVRRT--CTEEFQWSDSSPRCEEI--RCSDP 709
G C ++ W+ S C+E+ +CS P
Sbjct: 1448 SQGLGSNVIHCRKDGTWNGSFHVCQEMQGQCSVP 1481
Score = 61.3 bits (142), Expect = 2e-08
Identities = 74/317 (23%), Positives = 124/317 (39%), Gaps = 40/317 (12%)
Query: 641 CEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPR 700
CE DC +L + ++ + + G+ SC T Y L +RR +E S + P
Sbjct: 1210 CEKTDCPEL-AVENASLNCSSSDRYHGAQCTVSCRTGYVL--QIRRD--DELIKSQTGPS 1264
Query: 701 ----CEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKG 756
C E + + + E S+ + H + S + G T+ G+ ++C
Sbjct: 1265 VTVTCTEGKWNKQVACEPVDCSIPDH-----HQVYAASFSCPEGTTF--GSQCSFQCRHP 1317
Query: 757 YKVIGE-SLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLP---SNATFYGATAFYQ 812
++ G SL TC ++G WS C+ + C P + N + N G+ Y+
Sbjct: 1318 AQLKGNNSLLTCMEDGLWSFPEALCELM-CLAPPPVPNADLQTARCRENKHKVGSFCKYK 1376
Query: 813 CDENWELEGVIRR--------MCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTST 864
C + + G R+ C ++G+W + C +TC P + GL T+
Sbjct: 1377 CKPGYHVPGSSRKSKKRAFKTQCTQDGSW--QEGACVPVTCDPPPPKF---HGLYQCTNG 1431
Query: 865 LSIGGEAHYQCERGYNLKGHQTRT--CISKGQWNGTVPVCIPI--DCRSPGNI-ENGKIV 919
E +CE +G + C G WNG+ VC + C P + N K+
Sbjct: 1432 FQFNSECRIKCEDSDASQGLGSNVIHCRKDGTWNGSFHVCQEMQGQCSVPNELNSNLKLQ 1491
Query: 920 ISNGSTLFGSSVEYYCL 936
+G + GS CL
Sbjct: 1492 CPDGYAI-GSECATSCL 1507
Score = 46.8 bits (106), Expect = 4e-04
Identities = 30/82 (36%), Positives = 40/82 (48%), Gaps = 6/82 (7%)
Query: 886 TRTCISKGQWNGTVPVCIPIDCRSPGN--IENGKIVISNGSTLFGSSVEYYCLSQYQRVG 943
T TC ++G+WN V C P+DC P + + G+T FGS + C Q G
Sbjct: 1266 TVTC-TEGKWNKQV-ACEPVDCSIPDHHQVYAASFSCPEGTT-FGSQCSFQCRHPAQLKG 1322
Query: 944 P-FLRKCLDDGRWSGEEPSCEL 964
L C++DG WS E CEL
Sbjct: 1323 NNSLLTCMEDGLWSFPEALCEL 1344
Score = 32.3 bits (70), Expect = 9.7
Identities = 19/62 (30%), Positives = 26/62 (41%), Gaps = 3/62 (4%)
Query: 349 LPPTCGSPD-KLLNTTILGNDYDVGSRIVYKCPEGHML--LGDKSRHCKKDGFWSGAPPS 405
+P TC P K N + S KC + LG HC+KDG W+G+
Sbjct: 1411 VPVTCDPPPPKFHGLYQCTNGFQFNSECRIKCEDSDASQGLGSNVIHCRKDGTWNGSFHV 1470
Query: 406 CK 407
C+
Sbjct: 1471 CQ 1472
>AL691426-1|CAI16715.1| 1627|Homo sapiens pregnancy-associated plasma
protein A, pappalysinadenine nucleotide translocato
protein.
Length = 1627
Score = 70.9 bits (166), Expect = 2e-11
Identities = 68/280 (24%), Positives = 113/280 (40%), Gaps = 34/280 (12%)
Query: 701 CEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVI 760
CE+ C + + E + ++ + +DR HG + V R L+K + V
Sbjct: 1210 CEKTDCPE-LAVENASLNCSSSDRYHGAQCTVSCRTGYVLQIRRDDELIKSQTGPSVTV- 1267
Query: 761 GESLSTCEDNGQWSGTTPTCQYVDCGNPG--RIENGKVTLPSNATFYGATAFYQCDENWE 818
TC + G+W+ C+ VDC P ++ + P TF G+ +QC +
Sbjct: 1268 -----TCTE-GKWNKQV-ACEPVDCSIPDHHQVYAASFSCPEGTTF-GSQCSFQCRHPAQ 1319
Query: 819 LEGVIRRM-CQENGTWSLEPPICKEITC----PDPSAQIKAGSGLLVVTSTLSIGGEAHY 873
L+G + C E+G WS +C E+ C P P+A ++ + +G Y
Sbjct: 1320 LKGNNSLLTCMEDGLWSFPEALC-ELMCLAPPPVPNADLQTAR---CRENKHKVGSFCKY 1375
Query: 874 QCERGYNLKGHQTRT--------CISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGST 925
+C+ GY++ G ++ C G W C+P+ C P +G +NG
Sbjct: 1376 KCKPGYHVPGSSRKSKKRAFKTQCTQDGSWQEGA--CVPVTCDPPPPKFHGLYQCTNGFQ 1433
Query: 926 LFGSSVEYYCLSQ--YQRVGPFLRKCLDDGRWSGEEPSCE 963
F S C Q +G + C DG W+G C+
Sbjct: 1434 -FNSECRIKCEDSDASQGLGSNVIHCRKDGTWNGSFHVCQ 1472
Score = 68.9 bits (161), Expect = 9e-11
Identities = 74/274 (27%), Positives = 108/274 (39%), Gaps = 42/274 (15%)
Query: 471 CPDPPAVSNASVTVNGHKA--GSLASYTCENGHILS-------------GSTSVTCTLGG 515
CP+ AV NAS+ + G+ + +C G++L S +VTCT G
Sbjct: 1215 CPEL-AVENASLNCSSSDRYHGAQCTVSCRTGYVLQIRRDDELIKSQTGPSVTVTCT-EG 1272
Query: 516 AWSGVPPSCKYVNCGTPTIHK---GSFVLINGTTTYGSIAQFTCEPDYWLNGAEELV-CN 571
W+ +C+ V+C P H+ SF GTT +GS F C L G L+ C
Sbjct: 1273 KWNK-QVACEPVDCSIPDHHQVYAASFSCPEGTT-FGSQCSFQCRHPAQLKGNNSLLTCM 1330
Query: 572 RDGKWSYDIPSCELTSCPEPEVPSGGYMEA----FDYYVHSTINFHCEAGHKLIGEP--- 624
DG WS+ CEL P VP+ A + V S + C+ G+ + G
Sbjct: 1331 EDGLWSFPEALCELMCLAPPPVPNADLQTARCRENKHKVGSFCKYKCKPGYHVPGSSRKS 1390
Query: 625 -----NLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYR 679
C QDG W C + C P +G + NG S + C +
Sbjct: 1391 KKRAFKTQCTQDGSW--QEGACVPVTCDPPPPKFHGLYQCTNG-FQFNSECRIKCEDSDA 1447
Query: 680 LVGPVRRT--CTEEFQWSDSSPRCEEI--RCSDP 709
G C ++ W+ S C+E+ +CS P
Sbjct: 1448 SQGLGSNVIHCRKDGTWNGSFHVCQEMQGQCSVP 1481
Score = 61.3 bits (142), Expect = 2e-08
Identities = 74/317 (23%), Positives = 124/317 (39%), Gaps = 40/317 (12%)
Query: 641 CEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPR 700
CE DC +L + ++ + + G+ SC T Y L +RR +E S + P
Sbjct: 1210 CEKTDCPEL-AVENASLNCSSSDRYHGAQCTVSCRTGYVL--QIRRD--DELIKSQTGPS 1264
Query: 701 ----CEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKG 756
C E + + + E S+ + H + S + G T+ G+ ++C
Sbjct: 1265 VTVTCTEGKWNKQVACEPVDCSIPDH-----HQVYAASFSCPEGTTF--GSQCSFQCRHP 1317
Query: 757 YKVIGE-SLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLP---SNATFYGATAFYQ 812
++ G SL TC ++G WS C+ + C P + N + N G+ Y+
Sbjct: 1318 AQLKGNNSLLTCMEDGLWSFPEALCELM-CLAPPPVPNADLQTARCRENKHKVGSFCKYK 1376
Query: 813 CDENWELEGVIRR--------MCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTST 864
C + + G R+ C ++G+W + C +TC P + GL T+
Sbjct: 1377 CKPGYHVPGSSRKSKKRAFKTQCTQDGSW--QEGACVPVTCDPPPPKF---HGLYQCTNG 1431
Query: 865 LSIGGEAHYQCERGYNLKGHQTRT--CISKGQWNGTVPVCIPI--DCRSPGNI-ENGKIV 919
E +CE +G + C G WNG+ VC + C P + N K+
Sbjct: 1432 FQFNSECRIKCEDSDASQGLGSNVIHCRKDGTWNGSFHVCQEMQGQCSVPNELNSNLKLQ 1491
Query: 920 ISNGSTLFGSSVEYYCL 936
+G + GS CL
Sbjct: 1492 CPDGYAI-GSECATSCL 1507
Score = 46.8 bits (106), Expect = 4e-04
Identities = 30/82 (36%), Positives = 40/82 (48%), Gaps = 6/82 (7%)
Query: 886 TRTCISKGQWNGTVPVCIPIDCRSPGN--IENGKIVISNGSTLFGSSVEYYCLSQYQRVG 943
T TC ++G+WN V C P+DC P + + G+T FGS + C Q G
Sbjct: 1266 TVTC-TEGKWNKQV-ACEPVDCSIPDHHQVYAASFSCPEGTT-FGSQCSFQCRHPAQLKG 1322
Query: 944 P-FLRKCLDDGRWSGEEPSCEL 964
L C++DG WS E CEL
Sbjct: 1323 NNSLLTCMEDGLWSFPEALCEL 1344
Score = 32.3 bits (70), Expect = 9.7
Identities = 19/62 (30%), Positives = 26/62 (41%), Gaps = 3/62 (4%)
Query: 349 LPPTCGSPD-KLLNTTILGNDYDVGSRIVYKCPEGHML--LGDKSRHCKKDGFWSGAPPS 405
+P TC P K N + S KC + LG HC+KDG W+G+
Sbjct: 1411 VPVTCDPPPPKFHGLYQCTNGFQFNSECRIKCEDSDASQGLGSNVIHCRKDGTWNGSFHV 1470
Query: 406 CK 407
C+
Sbjct: 1471 CQ 1472
>AL353141-1|CAI16083.1| 1627|Homo sapiens pregnancy-associated plasma
protein A, pappalysinmolog A (yeast) (TIMM17A) pseu
protein.
Length = 1627
Score = 70.9 bits (166), Expect = 2e-11
Identities = 68/280 (24%), Positives = 113/280 (40%), Gaps = 34/280 (12%)
Query: 701 CEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVI 760
CE+ C + + E + ++ + +DR HG + V R L+K + V
Sbjct: 1210 CEKTDCPE-LAVENASLNCSSSDRYHGAQCTVSCRTGYVLQIRRDDELIKSQTGPSVTV- 1267
Query: 761 GESLSTCEDNGQWSGTTPTCQYVDCGNPG--RIENGKVTLPSNATFYGATAFYQCDENWE 818
TC + G+W+ C+ VDC P ++ + P TF G+ +QC +
Sbjct: 1268 -----TCTE-GKWNKQV-ACEPVDCSIPDHHQVYAASFSCPEGTTF-GSQCSFQCRHPAQ 1319
Query: 819 LEGVIRRM-CQENGTWSLEPPICKEITC----PDPSAQIKAGSGLLVVTSTLSIGGEAHY 873
L+G + C E+G WS +C E+ C P P+A ++ + +G Y
Sbjct: 1320 LKGNNSLLTCMEDGLWSFPEALC-ELMCLAPPPVPNADLQTAR---CRENKHKVGSFCKY 1375
Query: 874 QCERGYNLKGHQTRT--------CISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGST 925
+C+ GY++ G ++ C G W C+P+ C P +G +NG
Sbjct: 1376 KCKPGYHVPGSSRKSKKRAFKTQCTQDGSWQEGA--CVPVTCDPPPPKFHGLYQCTNGFQ 1433
Query: 926 LFGSSVEYYCLSQ--YQRVGPFLRKCLDDGRWSGEEPSCE 963
F S C Q +G + C DG W+G C+
Sbjct: 1434 -FNSECRIKCEDSDASQGLGSNVIHCRKDGTWNGSFHVCQ 1472
Score = 68.9 bits (161), Expect = 9e-11
Identities = 74/274 (27%), Positives = 108/274 (39%), Gaps = 42/274 (15%)
Query: 471 CPDPPAVSNASVTVNGHKA--GSLASYTCENGHILS-------------GSTSVTCTLGG 515
CP+ AV NAS+ + G+ + +C G++L S +VTCT G
Sbjct: 1215 CPEL-AVENASLNCSSSDRYHGAQCTVSCRTGYVLQIRRDDELIKSQTGPSVTVTCT-EG 1272
Query: 516 AWSGVPPSCKYVNCGTPTIHK---GSFVLINGTTTYGSIAQFTCEPDYWLNGAEELV-CN 571
W+ +C+ V+C P H+ SF GTT +GS F C L G L+ C
Sbjct: 1273 KWNK-QVACEPVDCSIPDHHQVYAASFSCPEGTT-FGSQCSFQCRHPAQLKGNNSLLTCM 1330
Query: 572 RDGKWSYDIPSCELTSCPEPEVPSGGYMEA----FDYYVHSTINFHCEAGHKLIGEP--- 624
DG WS+ CEL P VP+ A + V S + C+ G+ + G
Sbjct: 1331 EDGLWSFPEALCELMCLAPPPVPNADLQTARCRENKHKVGSFCKYKCKPGYHVPGSSRKS 1390
Query: 625 -----NLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYR 679
C QDG W C + C P +G + NG S + C +
Sbjct: 1391 KKRAFKTQCTQDGSW--QEGACVPVTCDPPPPKFHGLYQCTNG-FQFNSECRIKCEDSDA 1447
Query: 680 LVGPVRRT--CTEEFQWSDSSPRCEEI--RCSDP 709
G C ++ W+ S C+E+ +CS P
Sbjct: 1448 SQGLGSNVIHCRKDGTWNGSFHVCQEMQGQCSVP 1481
Score = 61.3 bits (142), Expect = 2e-08
Identities = 74/317 (23%), Positives = 124/317 (39%), Gaps = 40/317 (12%)
Query: 641 CEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPR 700
CE DC +L + ++ + + G+ SC T Y L +RR +E S + P
Sbjct: 1210 CEKTDCPEL-AVENASLNCSSSDRYHGAQCTVSCRTGYVL--QIRRD--DELIKSQTGPS 1264
Query: 701 ----CEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKG 756
C E + + + E S+ + H + S + G T+ G+ ++C
Sbjct: 1265 VTVTCTEGKWNKQVACEPVDCSIPDH-----HQVYAASFSCPEGTTF--GSQCSFQCRHP 1317
Query: 757 YKVIGE-SLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLP---SNATFYGATAFYQ 812
++ G SL TC ++G WS C+ + C P + N + N G+ Y+
Sbjct: 1318 AQLKGNNSLLTCMEDGLWSFPEALCELM-CLAPPPVPNADLQTARCRENKHKVGSFCKYK 1376
Query: 813 CDENWELEGVIRR--------MCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTST 864
C + + G R+ C ++G+W + C +TC P + GL T+
Sbjct: 1377 CKPGYHVPGSSRKSKKRAFKTQCTQDGSW--QEGACVPVTCDPPPPKF---HGLYQCTNG 1431
Query: 865 LSIGGEAHYQCERGYNLKGHQTRT--CISKGQWNGTVPVCIPI--DCRSPGNI-ENGKIV 919
E +CE +G + C G WNG+ VC + C P + N K+
Sbjct: 1432 FQFNSECRIKCEDSDASQGLGSNVIHCRKDGTWNGSFHVCQEMQGQCSVPNELNSNLKLQ 1491
Query: 920 ISNGSTLFGSSVEYYCL 936
+G + GS CL
Sbjct: 1492 CPDGYAI-GSECATSCL 1507
Score = 46.8 bits (106), Expect = 4e-04
Identities = 30/82 (36%), Positives = 40/82 (48%), Gaps = 6/82 (7%)
Query: 886 TRTCISKGQWNGTVPVCIPIDCRSPGN--IENGKIVISNGSTLFGSSVEYYCLSQYQRVG 943
T TC ++G+WN V C P+DC P + + G+T FGS + C Q G
Sbjct: 1266 TVTC-TEGKWNKQV-ACEPVDCSIPDHHQVYAASFSCPEGTT-FGSQCSFQCRHPAQLKG 1322
Query: 944 P-FLRKCLDDGRWSGEEPSCEL 964
L C++DG WS E CEL
Sbjct: 1323 NNSLLTCMEDGLWSFPEALCEL 1344
Score = 32.3 bits (70), Expect = 9.7
Identities = 19/62 (30%), Positives = 26/62 (41%), Gaps = 3/62 (4%)
Query: 349 LPPTCGSPD-KLLNTTILGNDYDVGSRIVYKCPEGHML--LGDKSRHCKKDGFWSGAPPS 405
+P TC P K N + S KC + LG HC+KDG W+G+
Sbjct: 1411 VPVTCDPPPPKFHGLYQCTNGFQFNSECRIKCEDSDASQGLGSNVIHCRKDGTWNGSFHV 1470
Query: 406 CK 407
C+
Sbjct: 1471 CQ 1472
>AL137024-5|CAI14281.1| 1627|Homo sapiens pregnancy-associated plasma
protein A, pappalysin) (TERF1) pseudogene protein.
Length = 1627
Score = 70.9 bits (166), Expect = 2e-11
Identities = 68/280 (24%), Positives = 113/280 (40%), Gaps = 34/280 (12%)
Query: 701 CEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKGYKVI 760
CE+ C + + E + ++ + +DR HG + V R L+K + V
Sbjct: 1210 CEKTDCPE-LAVENASLNCSSSDRYHGAQCTVSCRTGYVLQIRRDDELIKSQTGPSVTV- 1267
Query: 761 GESLSTCEDNGQWSGTTPTCQYVDCGNPG--RIENGKVTLPSNATFYGATAFYQCDENWE 818
TC + G+W+ C+ VDC P ++ + P TF G+ +QC +
Sbjct: 1268 -----TCTE-GKWNKQV-ACEPVDCSIPDHHQVYAASFSCPEGTTF-GSQCSFQCRHPAQ 1319
Query: 819 LEGVIRRM-CQENGTWSLEPPICKEITC----PDPSAQIKAGSGLLVVTSTLSIGGEAHY 873
L+G + C E+G WS +C E+ C P P+A ++ + +G Y
Sbjct: 1320 LKGNNSLLTCMEDGLWSFPEALC-ELMCLAPPPVPNADLQTAR---CRENKHKVGSFCKY 1375
Query: 874 QCERGYNLKGHQTRT--------CISKGQWNGTVPVCIPIDCRSPGNIENGKIVISNGST 925
+C+ GY++ G ++ C G W C+P+ C P +G +NG
Sbjct: 1376 KCKPGYHVPGSSRKSKKRAFKTQCTQDGSWQEGA--CVPVTCDPPPPKFHGLYQCTNGFQ 1433
Query: 926 LFGSSVEYYCLSQ--YQRVGPFLRKCLDDGRWSGEEPSCE 963
F S C Q +G + C DG W+G C+
Sbjct: 1434 -FNSECRIKCEDSDASQGLGSNVIHCRKDGTWNGSFHVCQ 1472
Score = 68.9 bits (161), Expect = 9e-11
Identities = 74/274 (27%), Positives = 108/274 (39%), Gaps = 42/274 (15%)
Query: 471 CPDPPAVSNASVTVNGHKA--GSLASYTCENGHILS-------------GSTSVTCTLGG 515
CP+ AV NAS+ + G+ + +C G++L S +VTCT G
Sbjct: 1215 CPEL-AVENASLNCSSSDRYHGAQCTVSCRTGYVLQIRRDDELIKSQTGPSVTVTCT-EG 1272
Query: 516 AWSGVPPSCKYVNCGTPTIHK---GSFVLINGTTTYGSIAQFTCEPDYWLNGAEELV-CN 571
W+ +C+ V+C P H+ SF GTT +GS F C L G L+ C
Sbjct: 1273 KWNK-QVACEPVDCSIPDHHQVYAASFSCPEGTT-FGSQCSFQCRHPAQLKGNNSLLTCM 1330
Query: 572 RDGKWSYDIPSCELTSCPEPEVPSGGYMEA----FDYYVHSTINFHCEAGHKLIGEP--- 624
DG WS+ CEL P VP+ A + V S + C+ G+ + G
Sbjct: 1331 EDGLWSFPEALCELMCLAPPPVPNADLQTARCRENKHKVGSFCKYKCKPGYHVPGSSRKS 1390
Query: 625 -----NLVCQQDGEWSGDSPTCEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYR 679
C QDG W C + C P +G + NG S + C +
Sbjct: 1391 KKRAFKTQCTQDGSW--QEGACVPVTCDPPPPKFHGLYQCTNG-FQFNSECRIKCEDSDA 1447
Query: 680 LVGPVRRT--CTEEFQWSDSSPRCEEI--RCSDP 709
G C ++ W+ S C+E+ +CS P
Sbjct: 1448 SQGLGSNVIHCRKDGTWNGSFHVCQEMQGQCSVP 1481
Score = 61.3 bits (142), Expect = 2e-08
Identities = 74/317 (23%), Positives = 124/317 (39%), Gaps = 40/317 (12%)
Query: 641 CEYIDCGKLPTLPYGTMELLNGTTHLGSVIQYSCTTNYRLVGPVRRTCTEEFQWSDSSPR 700
CE DC +L + ++ + + G+ SC T Y L +RR +E S + P
Sbjct: 1210 CEKTDCPEL-AVENASLNCSSSDRYHGAQCTVSCRTGYVL--QIRRD--DELIKSQTGPS 1264
Query: 701 ----CEEIRCSDPIVAEKSIVSVTGNDRSHGHTLIRTSDNRDVGNTYRIGALVKYRCEKG 756
C E + + + E S+ + H + S + G T+ G+ ++C
Sbjct: 1265 VTVTCTEGKWNKQVACEPVDCSIPDH-----HQVYAASFSCPEGTTF--GSQCSFQCRHP 1317
Query: 757 YKVIGE-SLSTCEDNGQWSGTTPTCQYVDCGNPGRIENGKVTLP---SNATFYGATAFYQ 812
++ G SL TC ++G WS C+ + C P + N + N G+ Y+
Sbjct: 1318 AQLKGNNSLLTCMEDGLWSFPEALCELM-CLAPPPVPNADLQTARCRENKHKVGSFCKYK 1376
Query: 813 CDENWELEGVIRR--------MCQENGTWSLEPPICKEITCPDPSAQIKAGSGLLVVTST 864
C + + G R+ C ++G+W + C +TC P + GL T+
Sbjct: 1377 CKPGYHVPGSSRKSKKRAFKTQCTQDGSW--QEGACVPVTCDPPPPKF---HGLYQCTNG 1431
Query: 865 LSIGGEAHYQCERGYNLKGHQTRT--CISKGQWNGTVPVCIPI--DCRSPGNI-ENGKIV 919
E +CE +G + C G WNG+ VC + C P + N K+
Sbjct: 1432 FQFNSECRIKCEDSDASQGLGSNVIHCRKDGTWNGSFHVCQEMQGQCSVPNELNSNLKLQ 1491
Query: 920 ISNGSTLFGSSVEYYCL 936
+G + GS CL
Sbjct: 1492 CPDGYAI-GSECATSCL 1507
Score = 46.8 bits (106), Expect = 4e-04
Identities = 30/82 (36%), Positives = 40/82 (48%), Gaps = 6/82 (7%)
Query: 886 TRTCISKGQWNGTVPVCIPIDCRSPGN--IENGKIVISNGSTLFGSSVEYYCLSQYQRVG 943
T TC ++G+WN V C P+DC P + + G+T FGS + C Q G
Sbjct: 1266 TVTC-TEGKWNKQV-ACEPVDCSIPDHHQVYAASFSCPEGTT-FGSQCSFQCRHPAQLKG 1322
Query: 944 P-FLRKCLDDGRWSGEEPSCEL 964
L C++DG WS E CEL
Sbjct: 1323 NNSLLTCMEDGLWSFPEALCEL 1344
Score = 32.3 bits (70), Expect = 9.7
Identities = 19/62 (30%), Positives = 26/62 (41%), Gaps = 3/62 (4%)
Query: 349 LPPTCGSPD-KLLNTTILGNDYDVGSRIVYKCPEGHML--LGDKSRHCKKDGFWSGAPPS 405
+P TC P K N + S KC + LG HC+KDG W+G+
Sbjct: 1411 VPVTCDPPPPKFHGLYQCTNGFQFNSECRIKCEDSDASQGLGSNVIHCRKDGTWNGSFHV 1470
Query: 406 CK 407
C+
Sbjct: 1471 CQ 1472
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.317 0.135 0.439
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 189,945,988
Number of Sequences: 224733
Number of extensions: 9141609
Number of successful extensions: 38661
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 424
Number of HSP's successfully gapped in prelim test: 261
Number of HSP's that attempted gapping in prelim test: 16571
Number of HSP's gapped (non-prelim): 8639
length of query: 1091
length of database: 73,234,838
effective HSP length: 98
effective length of query: 993
effective length of database: 51,211,004
effective search space: 50852526972
effective search space used: 50852526972
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.6 bits)
S2: 70 (32.3 bits)
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