Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA002120-TA|BGIBMGA002120-PA|IPR001300|Peptidase C2,
calpain, IPR000834|Peptidase M14, carboxypeptidase A
(510 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI0000D559F4 Cluster: PREDICTED: similar to CG3692-PA;... 428 e-118
UniRef50_Q9VXH6 Cluster: Calpain-C; n=5; Diptera|Rep: Calpain-C ... 317 4e-85
UniRef50_Q5DC34 Cluster: SJCHGC01809 protein; n=2; Schistosoma j... 171 4e-41
UniRef50_O14815 Cluster: Calpain-9; n=23; Euteleostomi|Rep: Calp... 168 3e-40
UniRef50_A7RJ83 Cluster: Predicted protein; n=1; Nematostella ve... 158 4e-37
UniRef50_Q9VT65 Cluster: Calpain-B (EC 3.4.22.-) (Calcium-activa... 156 1e-36
UniRef50_Q5SYF1 Cluster: Calpain 9; n=12; Theria|Rep: Calpain 9 ... 149 2e-34
UniRef50_Q66HU4 Cluster: Calpain 3,; n=5; Danio rerio|Rep: Calpa... 147 5e-34
UniRef50_Q5C3R6 Cluster: SJCHGC08992 protein; n=1; Schistosoma j... 147 5e-34
UniRef50_A7S7W7 Cluster: Predicted protein; n=1; Nematostella ve... 145 2e-33
UniRef50_P20807-2 Cluster: Isoform II of P20807 ; n=24; Tetrapod... 144 4e-33
UniRef50_UPI0000ECB984 Cluster: Calpain-3 (EC 3.4.22.54) (Calpai... 142 3e-32
UniRef50_Q9UMQ6 Cluster: Calpain-11; n=214; Euteleostomi|Rep: Ca... 133 1e-29
UniRef50_Q17E36 Cluster: Calpain, putative; n=2; Culicidae|Rep: ... 132 3e-29
UniRef50_Q4SVI4 Cluster: Chromosome 18 SCAF13757, whole genome s... 131 4e-29
UniRef50_UPI00006A0B93 Cluster: Calpain-12 (EC 3.4.22.-).; n=3; ... 131 5e-29
UniRef50_Q17E35 Cluster: Calpain, putative; n=3; Culicidae|Rep: ... 131 5e-29
UniRef50_Q4SDQ1 Cluster: Chromosome 10 SCAF14634, whole genome s... 127 8e-28
UniRef50_P27730 Cluster: Calpain; n=9; Schistosoma|Rep: Calpain ... 127 8e-28
UniRef50_UPI000065EF2F Cluster: Homolog of Homo sapiens "Calpain... 124 7e-27
UniRef50_P34308 Cluster: Calpain clp-1; n=5; Caenorhabditis eleg... 122 3e-26
UniRef50_Q4T7L5 Cluster: Chromosome 14 SCAF8084, whole genome sh... 121 5e-26
UniRef50_Q58EB1 Cluster: CAPN1 protein; n=10; Clupeocephala|Rep:... 116 1e-24
UniRef50_P20807 Cluster: Calpain-3; n=55; Euteleostomi|Rep: Calp... 111 4e-23
UniRef50_Q8MQV0 Cluster: Muscle-specific calpain; n=3; Pleocyema... 109 2e-22
UniRef50_UPI0000D9D3A6 Cluster: PREDICTED: similar to Calpain-2 ... 105 3e-21
UniRef50_UPI0000EBD30A Cluster: PREDICTED: similar to calpain Lp... 103 1e-20
UniRef50_Q9N4B2 Cluster: Calpain family protein 6; n=2; Caenorha... 103 1e-20
UniRef50_Q4SYK3 Cluster: Chromosome 10 SCAF12030, whole genome s... 98 4e-19
UniRef50_Q4SUI7 Cluster: Chromosome 16 SCAF13910, whole genome s... 98 6e-19
UniRef50_A7SN59 Cluster: Predicted protein; n=1; Nematostella ve... 98 6e-19
UniRef50_UPI0000D56B6A Cluster: PREDICTED: similar to calpain 11... 95 3e-18
UniRef50_Q4T7F6 Cluster: Chromosome undetermined SCAF8104, whole... 94 7e-18
UniRef50_Q4SQP6 Cluster: Chromosome undetermined SCAF14531, whol... 93 2e-17
UniRef50_Q8IAA9 Cluster: Calpain family protein 4, isoform a; n=... 93 2e-17
UniRef50_UPI000065EB25 Cluster: Homolog of Homo sapiens "Calpain... 91 8e-17
UniRef50_UPI00005A06A9 Cluster: PREDICTED: similar to Calpain-9 ... 90 1e-16
UniRef50_Q5IW11 Cluster: Calpain T; n=1; Gecarcinus lateralis|Re... 90 1e-16
UniRef50_UPI0000E7FFED Cluster: PREDICTED: similar to calpain 3;... 89 3e-16
UniRef50_UPI0000E45FAF Cluster: PREDICTED: similar to MGC81349 p... 89 3e-16
UniRef50_O15484 Cluster: Calpain-5; n=32; Deuterostomia|Rep: Cal... 88 5e-16
UniRef50_UPI00004D856D Cluster: Calpain-6 (Calpamodulin) (CalpM)... 83 2e-14
UniRef50_Q61A54 Cluster: Putative uncharacterized protein CBG139... 82 4e-14
UniRef50_Q16WJ3 Cluster: Calpain; n=2; Culicidae|Rep: Calpain - ... 79 2e-13
UniRef50_Q5TMZ6 Cluster: ENSANGP00000028181; n=1; Anopheles gamb... 75 6e-12
UniRef50_Q4SFI9 Cluster: Chromosome 7 SCAF14601, whole genome sh... 74 1e-11
UniRef50_Q17E42 Cluster: Calpain, putative; n=1; Aedes aegypti|R... 73 1e-11
UniRef50_Q6ZSI9 Cluster: Calpain-12; n=18; Mammalia|Rep: Calpain... 73 1e-11
UniRef50_Q17E39 Cluster: Putative uncharacterized protein; n=1; ... 71 6e-11
UniRef50_A7RJ84 Cluster: Predicted protein; n=1; Nematostella ve... 69 2e-10
UniRef50_Q9Y6Q1 Cluster: Calpain-6; n=13; Eutheria|Rep: Calpain-... 69 2e-10
UniRef50_Q6NW69 Cluster: Zgc:85932; n=7; Clupeocephala|Rep: Zgc:... 67 9e-10
UniRef50_UPI000065D0F1 Cluster: Homolog of Gallus gallus "Calpai... 66 2e-09
UniRef50_Q9HC96 Cluster: Calpain-10; n=35; Amniota|Rep: Calpain-... 63 1e-08
UniRef50_Q32NI7 Cluster: LOC733407 protein; n=2; Xenopus|Rep: LO... 62 3e-08
UniRef50_Q8RVL2 Cluster: Calpain-like protein; n=16; Magnoliophy... 61 6e-08
UniRef50_UPI0000EB2C11 Cluster: Calpain-11 (EC 3.4.22.-) (Calciu... 58 6e-07
UniRef50_Q4RQ29 Cluster: Chromosome 17 SCAF15006, whole genome s... 56 2e-06
UniRef50_Q22036 Cluster: Calpain-5; n=2; Caenorhabditis|Rep: Cal... 56 2e-06
UniRef50_Q55FS2 Cluster: Calpain-like cysteine protease; n=1; Di... 55 5e-06
UniRef50_Q4SWM0 Cluster: Chromosome undetermined SCAF13608, whol... 54 9e-06
UniRef50_Q4S467 Cluster: Chromosome undetermined SCAF14743, whol... 54 9e-06
UniRef50_Q66JI2 Cluster: Calpb protein; n=5; Xenopus|Rep: Calpb ... 54 1e-05
UniRef50_UPI0000F1E7D5 Cluster: PREDICTED: hypothetical protein;... 52 5e-05
UniRef50_Q4ST20 Cluster: Chromosome undetermined SCAF14317, whol... 50 1e-04
UniRef50_Q55BR8 Cluster: Calpain-like cysteine protease; n=2; Di... 48 6e-04
UniRef50_UPI0000F2B702 Cluster: PREDICTED: hypothetical protein;... 46 0.002
UniRef50_UPI0000499EFD Cluster: protein kinase; n=1; Entamoeba h... 45 0.004
UniRef50_A0CK52 Cluster: Chromosome undetermined scaffold_2, who... 45 0.004
UniRef50_UPI0000ECC95E Cluster: Calpain-13 (EC 3.4.22.-).; n=2; ... 45 0.005
UniRef50_O75808 Cluster: Calpain-15; n=13; Euteleostomi|Rep: Cal... 45 0.005
UniRef50_Q640X7 Cluster: MGC84330 protein; n=3; Tetrapoda|Rep: M... 44 0.013
UniRef50_Q6MZZ7 Cluster: Calpain-13; n=20; Mammalia|Rep: Calpain... 44 0.013
UniRef50_Q4RRV7 Cluster: Chromosome 7 SCAF15001, whole genome sh... 43 0.017
UniRef50_UPI0000D56690 Cluster: PREDICTED: similar to calpain 8;... 43 0.022
UniRef50_Q4S4V6 Cluster: Chromosome 2 SCAF14738, whole genome sh... 43 0.022
UniRef50_Q7QGN5 Cluster: ENSANGP00000018264; n=6; Endopterygota|... 42 0.039
UniRef50_Q4SWZ8 Cluster: Chromosome undetermined SCAF13274, whol... 41 0.089
UniRef50_A3BVQ3 Cluster: Putative uncharacterized protein; n=3; ... 40 0.12
UniRef50_Q5DBK8 Cluster: SJCHGC07600 protein; n=1; Schistosoma j... 40 0.16
UniRef50_A2E7M7 Cluster: Putative uncharacterized protein; n=3; ... 40 0.21
UniRef50_UPI0000D55C5A Cluster: PREDICTED: similar to CG1391-PB,... 39 0.36
UniRef50_Q1RL55 Cluster: Zinc finger protein; n=6; Chordata|Rep:... 38 0.48
UniRef50_UPI0001555C79 Cluster: PREDICTED: similar to calpain 1,... 38 0.63
UniRef50_UPI0000D6828A Cluster: PREDICTED: hypothetical protein;... 38 0.83
UniRef50_Q0DH47 Cluster: Os05g0491900 protein; n=2; Oryza sativa... 38 0.83
UniRef50_Q4DSV7 Cluster: Calpain-like cysteine peptidase, putati... 38 0.83
UniRef50_Q6DCQ4 Cluster: Capn3-prov protein; n=2; Xenopus|Rep: C... 37 1.1
UniRef50_O29691 Cluster: Uncharacterized protein AF_0562; n=1; A... 37 1.1
UniRef50_Q7PZT3 Cluster: ENSANGP00000016570; n=1; Anopheles gamb... 36 1.9
UniRef50_A1CRW2 Cluster: Calpain-like protease, putative; n=1; A... 36 1.9
UniRef50_P27398 Cluster: Calpain-D; n=8; Eumetazoa|Rep: Calpain-... 36 1.9
UniRef50_UPI00015B504A Cluster: PREDICTED: similar to small opti... 36 2.5
UniRef50_UPI000051A8C7 Cluster: PREDICTED: similar to small opti... 36 2.5
UniRef50_UPI000049A315 Cluster: calpain-like cysteine protease; ... 36 2.5
UniRef50_Q9FYE4 Cluster: EF-hand Calcium binding protein-like; n... 36 2.5
UniRef50_Q96294 Cluster: Calcium-dependent protein kinase; n=5; ... 36 2.5
UniRef50_Q4RV78 Cluster: Chromosome 15 SCAF14992, whole genome s... 36 3.4
UniRef50_A7NZQ0 Cluster: Chromosome chr6 scaffold_3, whole genom... 36 3.4
UniRef50_A3C8D9 Cluster: Putative uncharacterized protein; n=3; ... 36 3.4
UniRef50_A6S7E5 Cluster: Putative uncharacterized protein; n=2; ... 36 3.4
UniRef50_Q17A99 Cluster: Adaptin, alpha/gamma/epsilon; n=2; Culi... 35 4.4
UniRef50_Q0U7G1 Cluster: Putative uncharacterized protein; n=1; ... 35 4.4
UniRef50_Q012Z6 Cluster: CG1391-PB, isoform B; n=2; Ostreococcus... 35 5.9
UniRef50_O65644 Cluster: Calcium-dependent serine/threonine prot... 35 5.9
UniRef50_UPI0000E480BA Cluster: PREDICTED: similar to toll-like ... 34 7.8
UniRef50_Q6AQY3 Cluster: Related to outer membrane (Agglutinatio... 34 7.8
UniRef50_Q8X0W5 Cluster: Related to micromolar calcium activated... 34 7.8
UniRef50_A2QVX3 Cluster: Contig An11c0110, complete genome; n=1;... 34 7.8
UniRef50_Q06850 Cluster: Calcium-dependent protein kinase isofor... 34 7.8
>UniRef50_UPI0000D559F4 Cluster: PREDICTED: similar to CG3692-PA;
n=3; Endopterygota|Rep: PREDICTED: similar to CG3692-PA
- Tribolium castaneum
Length = 697
Score = 428 bits (1055), Expect = e-118
Identities = 234/478 (48%), Positives = 303/478 (63%), Gaps = 35/478 (7%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVMPELSDGSA--LRTLLDTSSVVTAHYFPPV 106
+LHGSYEALKYGSLLDGLADLTGGITESI + + + A L LLD +S++T PP
Sbjct: 211 KLHGSYEALKYGSLLDGLADLTGGITESIPIRQDATTCARLLHKLLDMTSIITCTVQPPN 270
Query: 107 TIISVFFLSLPTGIRLVKIRLRRSVINIFQVDT-TNEPVYLIRLRRPLGHGETPISHIVL 165
+ LP GI+L V + +V+T + E V L++LR LG + +
Sbjct: 271 FQMRSSVEKLPNGIQL---GTNYRVYLVERVETYSGEAVQLVKLRNALGPASEYVGPWSI 327
Query: 166 DTALWKTIPQYERDRLMTA-SKG-VWMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQK 223
D+ W + +RL + S+G WM + DF + F +E++HLD++TSR E SL K
Sbjct: 328 DSPEWSEVSPNSLERLHSELSEGEFWMSYPDFIKTFTHMEVIHLDSDTSRDEPSLHNKNT 387
Query: 224 WQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPDTVIISLNQHSIMEPKVIGFS 283
WQM+++QG W +GVSAGGCRN FH NPQ+ ++L+E + V++SLNQHSIMEPKVIGF+
Sbjct: 388 WQMRLYQGNWLKGVSAGGCRNNPETFHINPQLHLLLSEMEEVVVSLNQHSIMEPKVIGFT 447
Query: 284 VYKMPKFLTETANQMFFKRIKSTINSQYTNSRQVSQRCQLESGAYLIMPTTFEPREEAQF 343
Y +PK TET + FFK KS NSQYTNSRQVS RC LE G YLI+PT FEP +E+ F
Sbjct: 448 AYSIPKSNTETIGKSFFKANKSLFNSQYTNSRQVSYRCYLEQGGYLIIPTIFEPGQESGF 507
Query: 344 TLRIYSNKPLKMKVLDDPPQMTKAALVKAPPGSDSNGFFQYETLFLQLADAHRTIDIFEL 403
TLR+YS+KPLK+K+LD P + K+A+VKAPP D F QYE +FLQLAD HRT++ FEL
Sbjct: 508 TLRVYSSKPLKLKLLDTVPLLLKSAIVKAPPLLDGKSFSQYEAVFLQLADEHRTVNAFEL 567
Query: 404 QELLDACLPNDYIKSCVSIDTLKHLQLVFKTHAREKMGVLRVERLRDALK---------- 453
QELLDACLPNDYIKSC SI+ + + L F T ++ + L +LK
Sbjct: 568 QELLDACLPNDYIKSCASIEVCRQVILTFDTSGTGRLKFSDFKDLMCSLKFWQTSFKNHT 627
Query: 454 --DVGFIVPER---------------VISLLVFRYMRKDGMLRFGDFVSAVMHLHRVF 494
G + ER V++ L+ RYMRKDG LRFGDFVSA++HL F
Sbjct: 628 KEKTGILKAERFRDALQAVGFQLSSDVLATLILRYMRKDGTLRFGDFVSAILHLTVAF 685
Score = 64.1 bits (149), Expect = 8e-09
Identities = 30/38 (78%), Positives = 32/38 (84%), Gaps = 1/38 (2%)
Query: 13 DKWLVSCLGVLYLCKGLFYRVVPADQRMD-TSYAGVFR 49
D+WLVSCLGVLYL KGLFYRVVPADQ + YAGVFR
Sbjct: 127 DRWLVSCLGVLYLNKGLFYRVVPADQSFNGDQYAGVFR 164
>UniRef50_Q9VXH6 Cluster: Calpain-C; n=5; Diptera|Rep: Calpain-C -
Drosophila melanogaster (Fruit fly)
Length = 681
Score = 317 bits (779), Expect = 4e-85
Identities = 198/500 (39%), Positives = 279/500 (55%), Gaps = 53/500 (10%)
Query: 47 VFRLHGSYEALKYGSLLDGLADLTGGITESIVMPELSDG---SALRTLLDTSSVVTAHYF 103
+ +LHGSYEALKYG+ DGL DL GG+ MP L+D L+ LL T+ +VT
Sbjct: 163 IAKLHGSYEALKYGTRSDGLTDLLGGVVRQ--MPILADNIRPQTLKELLTTTCIVTCLAD 220
Query: 104 PPVTIISVFFLS-LPTGIRLVKIRLRRSVINIFQVDTTNEPVYLIRLR-----RPLGHGE 157
T+ +P GI LV + R S ++ + + V L+ L+ +P G
Sbjct: 221 KSATVAKKNLAERMPNGI-LVNVNYRLSSLDKVKT-LMGDSVQLVCLKDTFSSKPFGEKT 278
Query: 158 TPISHIVLDTALWKTIPQYERDRLMTA-SKG-VWMLFSDFQRLFPRIEMVHLDTETSRAE 215
+ + W+ + Q ER RL+ G W+ F DF +F +E+V+LDTETS E
Sbjct: 279 HFLGDWSPMSKTWERVSQVERARLIRQLGPGEFWLSFCDFVEIFSTMEVVYLDTETSNDE 338
Query: 216 LSLSEKQ-KWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPDTVIISLNQHSI 274
L + W+MKMHQG WKRGV+AGGCRN+ +F H NPQ+ I + + ++I+LNQH+
Sbjct: 339 EMLKSRPLHWKMKMHQGQWKRGVTAGGCRNHESF-HINPQLLISVQDEQDLVIALNQHTA 397
Query: 275 MEPKVIGFSVYKMPK--FLTETANQMFFKRIKSTINSQYTNSRQVSQRCQLESGAYLIMP 332
+EPKVIGF++Y L+E + FFK S +NS Y N+R VS LE+G Y+++P
Sbjct: 398 VEPKVIGFTMYTWDGEYMLSECLQKDFFKNHVSYLNSDYGNTRHVSYHTHLEAGHYVLIP 457
Query: 333 TTFEPREEAQFTLRIYSNKPLKMKVLD-------DPPQMTKAALVKAPPGSDSNGFFQYE 385
TT+EP EEA FT+RI ++ L+ DP K+ + G QYE
Sbjct: 458 TTYEPAEEAHFTVRILGTGSFRLSCLETQTMILLDPFPALKSTDAERCGGPKVKSVCQYE 517
Query: 386 TLFLQLADAHRTIDIFELQELLDACLPNDYIKSCVSIDTLKHLQLV-------------F 432
+++QLAD ++TI+ FEL ELL+ACLPNDYIK C +ID + + + F
Sbjct: 518 PVYMQLADENKTINCFELHELLEACLPNDYIKGCANIDICRQVIALQDRSGSGRITFQQF 577
Query: 433 KT--------------HAREKMGVLRVERLRDALKDVGFIVPERVISLLVFRYMRKDGML 478
KT + +EK G+LR ERLRDAL D+GF + +++ L+ RY+RKDG L
Sbjct: 578 KTFMVNLKSWQGVFKMYTKEKAGILRAERLRDALCDIGFQLSTDIMNCLIQRYIRKDGTL 637
Query: 479 RFGDFVSAVMHLHRVFVQVY 498
R DFVSAV+HL F Q +
Sbjct: 638 RLSDFVSAVIHLTTAFNQFH 657
Score = 54.0 bits (124), Expect = 9e-06
Identities = 24/39 (61%), Positives = 32/39 (82%), Gaps = 1/39 (2%)
Query: 11 VGDKWLVSCLGVLYLCKGLFYRVVPADQRMDTSYAGVFR 49
+GD+WLVSCLG+L + LFYRVVPADQ + +++ GVFR
Sbjct: 81 MGDRWLVSCLGLLSSLRNLFYRVVPADQTLASAH-GVFR 118
>UniRef50_Q5DC34 Cluster: SJCHGC01809 protein; n=2; Schistosoma
japonicum|Rep: SJCHGC01809 protein - Schistosoma
japonicum (Blood fluke)
Length = 773
Score = 171 bits (416), Expect = 4e-41
Identities = 147/495 (29%), Positives = 233/495 (47%), Gaps = 56/495 (11%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVMPELSDGSALRTLLDTSSVVTAHYFPPVTI 108
+L GSYEALK G+ + L D TGGI E + + + L+ +L + + +
Sbjct: 258 KLCGSYEALKGGTTSEALEDFTGGIFEMFDLKNETPPNLLQVMLKSQELSSLMACSIQAD 317
Query: 109 ISVFFLSLPTGIRLVKIRLRRSVINIFQVDTTNEP--VYLIRLRRPLGHGETPISHIVLD 166
+ F LP G+ + SV + + N+ + L+R+R P G E+ D
Sbjct: 318 PNTFEARLPNGLIMGHAYSVTSV-KLLDISVPNKTGKIPLVRVRNPWGD-ESEWKGAWSD 375
Query: 167 TAL-WKTIPQYERDRL-MTASKG--VWMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQ 222
+ W I +R +L +T WM + DF F ++E+ HL + S E+ +
Sbjct: 376 KSKEWSLISPEQRQQLGLTFDDDGEFWMSYQDFVSNFEKLEICHLGPQ-SMGEMQ--GNR 432
Query: 223 KWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPD--------TVIISLNQHSI 274
W+M + +G WKR VSAGGCRN+++ F NPQ + + +PD T+I+ L Q +
Sbjct: 433 VWEMCIEEGCWKRRVSAGGCRNFLDTFWINPQYVVSVEDPDENDEENKGTLIVGLMQKNR 492
Query: 275 MEPK-------VIGFSVYKMPKFLTETANQMFFKRIKSTINS-QYTNSRQVSQRCQLESG 326
+ + IG++VYK+P+ T + FFK S S + N R+V R +L+ G
Sbjct: 493 RKMRQEGADLLTIGYAVYKLPEQHQGTLDMKFFKYNASVARSPAFINLREVCGRHRLDPG 552
Query: 327 AYLIMPTTFEPREEAQFTLRIYSNKPLKMKVLDDPPQMTKAALVKAPPGSDSNGFFQYET 386
Y ++P+TF+P EEA+F LRI+S + LDD T+ A V P +D +
Sbjct: 553 HYAVIPSTFQPNEEAEFMLRIFSEEKRSTHELDDEIGETQPATV-VKPLTDVQ-VEALQK 610
Query: 387 LFLQLADAHRTIDIFELQELLDACLPNDY------IKSCVSI------------------ 422
F ++A ID EL+++L+ D+ ++SC S+
Sbjct: 611 AFNKVAGDDGEIDADELRDILNCAFTRDFTFDGFSLESCRSMIAMMDFDRSGMLSFPEFR 670
Query: 423 ---DTLKHLQLVFKTHAREKMGVLRVERLRDALKDVGFIVPERVISLLVFRYMRKDGMLR 479
D L+ + FK +K G + LR+ALK VGF + V S LV R+ R+DG +
Sbjct: 671 KLWDLLRVWKSAFKQFDVDKSGSMNSIELRNALKHVGFSINNSVFSTLVMRFSRRDGSVP 730
Query: 480 FGDFVSAVMHLHRVF 494
F +V L +F
Sbjct: 731 FDSYVICCARLQTLF 745
Score = 39.5 bits (88), Expect = 0.21
Identities = 17/41 (41%), Positives = 24/41 (58%)
Query: 11 VGDKWLVSCLGVLYLCKGLFYRVVPADQRMDTSYAGVFRLH 51
+GD WL++ + L + K LF +VV DQ Y G+FR H
Sbjct: 173 LGDCWLLAAIACLSMDKKLFEQVVAIDQSFTKEYCGLFRFH 213
>UniRef50_O14815 Cluster: Calpain-9; n=23; Euteleostomi|Rep:
Calpain-9 - Homo sapiens (Human)
Length = 690
Score = 168 bits (409), Expect = 3e-40
Identities = 146/491 (29%), Positives = 230/491 (46%), Gaps = 60/491 (12%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVMPELSDG--SALRTLLDTSSVVTAHYFPPV 106
+L+GSYEALK GS ++ + D TGG+ E+ E + L L S++ +
Sbjct: 179 KLNGSYEALKGGSAIEAMEDFTGGVAETFQTKEAPENFYEILEKALKRGSLLGCF----I 234
Query: 107 TIISVFFLSLPTGIRLVKIRLRRSVINIFQVDTTNEPVYLIRLRRPLGHGETPISHIVLD 166
S T L+K SV I QV + + LIR+R P G E S
Sbjct: 235 DTRSAAESEARTPFGLIKGHAY-SVTGIDQVSFRGQRIELIRIRNPWGQVEWNGSWSD-S 292
Query: 167 TALWKTIPQYERDRLMTASKG---VWMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQK 223
+ W+++ E+ RL + WM F DF+ F ++E+ +L + L K
Sbjct: 293 SPEWRSVGPAEQKRLCHTALDDGEFWMAFKDFKAHFDKVEICNLTPDA----LEEDAIHK 348
Query: 224 WQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPD------TVIISLNQHSIMEP 277
W++ +HQG W RG +AGGCRN+++ F TNPQ+++ L E D + +++L Q +
Sbjct: 349 WEVTVHQGSWVRGSTAGGCRNFLDTFWTNPQIKLSLTEKDEGQEECSFLVALMQKDRRKL 408
Query: 278 K-------VIGFSVYKMPKFLTETANQMFFKRIKSTINSQ-YTNSRQVSQRCQLESGAYL 329
K IG+++Y+ P E N+ FF+ S S+ + N R+VS R +L G Y+
Sbjct: 409 KRFGANVLTIGYAIYECPD-KDEHLNKDFFRYHASRARSKTFINLREVSDRFKLPPGEYI 467
Query: 330 IMPTTFEPREEAQFTLRIYSNKPLKMKVLDDPPQMTKAALVK-APPGSDSNGFFQYETLF 388
++P+TFEP +EA F LRI+S K + +D + K PP ++ ++ LF
Sbjct: 468 LIPSTFEPHQEADFCLRIFSEKKAITRDMDGNVDIDLPEPPKPTPPDQETEEEQRFRALF 527
Query: 389 LQLADAHRTIDIFELQELLDACLPNDY-IK-------SCVSI----DT------------ 424
Q+A + EL+ +L+A L IK SC +I DT
Sbjct: 528 EQVAGEDMEVTAEELEYVLNAVLQKKKDIKFKKLSLISCKNIISLMDTSGNGKLEFDEFK 587
Query: 425 -----LKHLQLVFKTHAREKMGVLRVERLRDALKDVGFIVPERVISLLVFRYMRKDGMLR 479
LK +F +K G + LR ALK GF + ++ L+V RY ++ L
Sbjct: 588 VFWDKLKQWINLFLRFDADKSGTMSTYELRTALKAAGFQLSSHLLQLIVLRYADEELQLD 647
Query: 480 FGDFVSAVMHL 490
F DF++ ++ L
Sbjct: 648 FDDFLNCLVRL 658
Score = 35.5 bits (78), Expect = 3.4
Identities = 15/38 (39%), Positives = 22/38 (57%)
Query: 11 VGDKWLVSCLGVLYLCKGLFYRVVPADQRMDTSYAGVF 48
+GD WL++ + L L + RV+P DQ YAG+F
Sbjct: 94 LGDCWLLAAIASLTLNQKALARVIPQDQSFGPGYAGIF 131
>UniRef50_A7RJ83 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 652
Score = 158 bits (383), Expect = 4e-37
Identities = 131/498 (26%), Positives = 234/498 (46%), Gaps = 59/498 (11%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVMPELSDG--SALRTLLDTSSVVTAHYFPPV 106
+L GSYEA+ G + + L D+TGG+ E++ + G + + + S++
Sbjct: 162 KLCGSYEAMSLGRISEALQDMTGGMIENVDLQNPPHGLFNVMMKAYERQSLMGCSIEVKK 221
Query: 107 TIISVFFLSLPTGI---RLVKIR-LRRSVINIFQVDTTNEPVYLIRLRRPLGHGETPISH 162
+ +L G+ I LR++ ++ + V LIRLR P +
Sbjct: 222 YSSDQYEGTLENGLITRHAYSITGLRKATLSSLR---GRPEVDLIRLRNPHANSSEWRGA 278
Query: 163 IVLDTALWKTIPQYERDRL-MTASKG--VWMLFSDFQRLFPRIEMVHLDTETSRAELSLS 219
+ W + E+ L +T WM F DF F R+E+ L ++ + +
Sbjct: 279 WSDRSPEWNMLSSQEKRELNLTFDDDGEFWMSFDDFLNNFTRLEICMLTPDS----MEQN 334
Query: 220 EKQKWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPD-------TVIISL--- 269
+++KW ++ +G W++GV+AGGCRN++ F+TNPQ ++ L PD TVI+SL
Sbjct: 335 DRRKWDVQNEKGRWQKGVTAGGCRNFIASFYTNPQFRVCLKNPDDDDDELCTVIVSLMRV 394
Query: 270 -NQHSIMEP--KVIGFSVYKMPKFLT--ETANQMFFKRIKS-TINSQYTNSRQVSQRCQL 323
+ H + P IGF++YK P + + ++ FF+ K+ + + ++ R++S R +L
Sbjct: 395 DHSHRVKIPDRAPIGFAIYKAPSDMRKGDRLDRAFFEYNKAVAMTTSFSKLREISSRYRL 454
Query: 324 ESGAYLIMPTTFEPREEAQFTLRIYSNKPLKMKVLDDPPQMTKAALVKAPPGSDSNGFFQ 383
+G Y+++P+TF P +E F LRI+S +P +D +MT V + +
Sbjct: 455 HAGEYVVIPSTFNPGQEGDFLLRIFSERPQYASEIDQETKMTSGPKVVITQDDAKSIDHE 514
Query: 384 YETLFLQLADAHRTIDIFELQELLDACLPNDY------IKSCVSI----DT--------- 424
+ +F Q+A +D +ELQE+L + +++C S+ DT
Sbjct: 515 FWDVFHQMAGEDGEVDQYELQEILSKSFTRELNNNLFALEACRSMISMFDTDRSGALGYN 574
Query: 425 -LKHLQLV-------FKTHAREKMGVLRVERLRDALKDVGFIVPERVISLLVFRYMRKDG 476
+ L ++ F + R+ G + LRDAL +G+ + +S LV RY K G
Sbjct: 575 EFRALMILLEKWKNHFHKYDRDHSGDMNAYELRDALNGLGYQLSNSAMSSLVLRYHNKRG 634
Query: 477 MLRFGDFVSAVMHLHRVF 494
+ F F+ V+ + +F
Sbjct: 635 TISFDTFIQIVVRVVVMF 652
>UniRef50_Q9VT65 Cluster: Calpain-B (EC 3.4.22.-) (Calcium-activated
neutral proteinase B) (CANP B) [Contains: Calpain-B
catalytic subunit 1; Calpain-B catalytic subunit 2];
n=4; Sophophora|Rep: Calpain-B (EC 3.4.22.-)
(Calcium-activated neutral proteinase B) (CANP B)
[Contains: Calpain-B catalytic subunit 1; Calpain-B
catalytic subunit 2] - Drosophila melanogaster (Fruit
fly)
Length = 925
Score = 156 bits (379), Expect = 1e-36
Identities = 131/509 (25%), Positives = 224/509 (44%), Gaps = 63/509 (12%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVMPELSDG--SALRTLLDTSSVVTAHYFPPV 106
+LHGSYEALK G+ + + D TGG+TE + E S + + S++ P
Sbjct: 396 KLHGSYEALKGGTTCEAMEDFTGGVTEWYDIKEAPPNLFSIMMKAAERGSMMGCSLEPDP 455
Query: 107 TIISVFFLSLPTG-IRLVKIRLRRSVINIFQVDTTNEPVYLIRLRRPLGHGETPISHIVL 165
++ P G IR + + + + +IR+R P G+
Sbjct: 456 HVLEA---ETPQGLIRGHAYSITKVCLMDISTPNRQGKLPMIRMRNPWGNDAEWSGPWSD 512
Query: 166 DTALWKTIPQYERDRL---MTASKGVWMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQ 222
+ W+ IP++ ++ + WM F DF F R+E+ +L ++ + S ++
Sbjct: 513 SSPEWRFIPEHTKEEIGLNFDRDGEFWMSFQDFLNHFDRVEICNLSPDSLTEDQQHSSRR 572
Query: 223 KWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPD--------TVIISLNQHSI 274
KW+M M +G W GV+AGGCRN++ F NPQ I L +PD T I++L Q +
Sbjct: 573 KWEMSMFEGEWTSGVTAGGCRNFLETFWHNPQYIISLEDPDDEDDDGKCTAIVALMQKNR 632
Query: 275 MEPK-------VIGFSVYKMPKFLTETANQ--MFFKRIKSTINS-QYTNSRQVSQRCQLE 324
+ IGF++Y + + Q FFK S S + N+R+V R +L
Sbjct: 633 RSKRNVGIDCLTIGFAIYHLTDRDMQVKPQGLNFFKYRASVARSPHFINTREVCARFKLP 692
Query: 325 SGAYLIMPTTFEPREEAQFTLRIYSNKPLKMKVLDD-------PPQMTKAALVKAPPGSD 377
G YLI+P+TF+P EE +F +R++S M+ DD ++ + P D
Sbjct: 693 PGHYLIVPSTFDPNEEGEFIIRVFSETRNNMEENDDEVGFGETDDRIAPSLPPPTPKEED 752
Query: 378 SNGFFQYETLFLQLADAHRTIDIFELQELLDACL----------PNDYIKSCVS------ 421
LF +A + +D EL+ +LD + D ++S V+
Sbjct: 753 DPQRIALRRLFDSVAGSDEEVDWQELKRILDHSMRDVMVGSDGFSKDAVRSMVAMLDKDR 812
Query: 422 ------------IDTLKHLQLVFKTHAREKMGVLRVERLRDALKDVGFIVPERVISLLVF 469
+ + + VFK + + G + LR AL G+ + R+++ L
Sbjct: 813 SGRLGFEEFEALLTDIAKWRAVFKLYDTRRTGSIDGFHLRGALNSAGYHLNNRLLNALAH 872
Query: 470 RYMRKDGMLRFGDFVSAVMHLHRVFVQVY 498
RY ++G + F DF+ + + R F++++
Sbjct: 873 RYGSREGQIPFDDFLMCAIKV-RTFIEMF 900
Score = 38.3 bits (85), Expect = 0.48
Identities = 19/58 (32%), Positives = 32/58 (55%), Gaps = 4/58 (6%)
Query: 11 VGDKWLVSCLGVLYLCKGLFYRVVPADQRMDTSYAGVFRLHGSYEALKYGSLLDGLAD 68
+GD WL++ L LF+RV+P DQ +YAG+F ++ +YG ++ + D
Sbjct: 311 LGDCWLLAAAANLTQDSTLFFRVIPPDQDFQENYAGIFH----FKFWQYGKWVEVVID 364
>UniRef50_Q5SYF1 Cluster: Calpain 9; n=12; Theria|Rep: Calpain 9 -
Homo sapiens (Human)
Length = 664
Score = 149 bits (361), Expect = 2e-34
Identities = 144/488 (29%), Positives = 222/488 (45%), Gaps = 80/488 (16%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVMPELSDG--SALRTLLDTSSVVTAHYFPPV 106
+L+GSYEALK GS ++ + D TGG+ E+ E + L L S++ +
Sbjct: 179 KLNGSYEALKGGSAIEAMEDFTGGVAETFQTKEAPENFYEILEKALKRGSLLGCF----I 234
Query: 107 TIISVFFLSLPTGIRLVKIRLRRSVINIFQVDTTNEPVYLIRLRRPLGHGETPISHIVLD 166
S T L+K SV I QV + + LIR+R P G E S
Sbjct: 235 DTRSAAESEARTPFGLIKGHAY-SVTGIDQVSFRGQRIELIRIRNPWGQVEWNGS----- 288
Query: 167 TALWKTIPQYERDRLMTASKGVWMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQKWQM 226
W DR M F DF+ F ++E+ +L + L KW++
Sbjct: 289 ---WS-------DR---------MAFKDFKAHFDKVEICNLTPDA----LEEDAIHKWEV 325
Query: 227 KMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPD------TVIISLNQHSIMEPK-- 278
+HQG W RG +AGGCRN+++ F TNPQ+++ L E D + +++L Q + K
Sbjct: 326 TVHQGSWVRGSTAGGCRNFLDTFWTNPQIKLSLTEKDEGQEECSFLVALMQKDRRKLKRF 385
Query: 279 -----VIGFSVYKMPKFLTETANQMFFKRIKSTINSQ-YTNSRQVSQRCQLESGAYLIMP 332
IG+++Y+ P E N+ FF+ S S+ + N R+VS R +L G Y+++P
Sbjct: 386 GANVLTIGYAIYECPD-KDEHLNKDFFRYHASRARSKTFINLREVSDRFKLPPGEYILIP 444
Query: 333 TTFEPREEAQFTLRIYSNKPLKMKVLDDPPQMTKAALVK-APPGSDSNGFFQYETLFLQL 391
+TFEP +EA F LRI+S K + +D + K PP ++ ++ LF Q+
Sbjct: 445 STFEPHQEADFCLRIFSEKKAITRDMDGNVDIDLPEPPKPTPPDQETEEEQRFRALFEQV 504
Query: 392 ADAHRTIDIFELQELLDACLPNDY-IK-------SCVSI----DT--------------- 424
A + EL+ +L+A L IK SC +I DT
Sbjct: 505 AGEDMEVTAEELEYVLNAVLQKKKDIKFKKLSLISCKNIISLMDTSGNGKLEFDEFKVFW 564
Query: 425 --LKHLQLVFKTHAREKMGVLRVERLRDALKDVGFIVPERVISLLVFRYMRKDGMLRFGD 482
LK +F +K G + LR ALK GF + ++ L+V RY ++ L F D
Sbjct: 565 DKLKQWINLFLRFDADKSGTMSTYELRTALKAAGFQLSSHLLQLIVLRYADEELQLDFDD 624
Query: 483 FVSAVMHL 490
F++ ++ L
Sbjct: 625 FLNCLVRL 632
Score = 35.5 bits (78), Expect = 3.4
Identities = 15/38 (39%), Positives = 22/38 (57%)
Query: 11 VGDKWLVSCLGVLYLCKGLFYRVVPADQRMDTSYAGVF 48
+GD WL++ + L L + RV+P DQ YAG+F
Sbjct: 94 LGDCWLLAAIASLTLNQKALARVIPQDQSFGPGYAGIF 131
>UniRef50_Q66HU4 Cluster: Calpain 3,; n=5; Danio rerio|Rep: Calpain
3, - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 725
Score = 147 bits (357), Expect = 5e-34
Identities = 112/372 (30%), Positives = 184/372 (49%), Gaps = 37/372 (9%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVMPELSDG--SALRTLLDTSSVVTAHYFPPV 106
+LHGSYEALK G+ +G+ D TGG+TE M E ++ L+ S++ V
Sbjct: 192 KLHGSYEALKGGNTAEGMEDFTGGVTEFYEMKEAPKELYKIMQKALERGSLMGCSIDSLV 251
Query: 107 TIISVFFLSLPTGIRLVKIRLRRSVINIFQVDTTNEPVYLIRLRRPLGHGET--PISHIV 164
+ F TG+ +V Q V L+RLR P G E P S
Sbjct: 252 P--ARFETRTATGLVKGHAYSVTAVEECKQSQQKESRVRLVRLRNPWGQVEWNGPWSD-- 307
Query: 165 LDTALWKTIPQYERDRLM--TASKG-VWMLFSDFQRLFPRIEMVHLDTETSRAELSLSEK 221
++ W+++ + E+++L A G WM F DF++ + +IE+ +L + L +
Sbjct: 308 -NSKEWESLSKAEKEKLQQQNAEDGEFWMSFEDFKKNYTKIEICNLTPDA----LEDDKL 362
Query: 222 QKWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPD----------TVIISLNQ 271
KW + +++G W RG SAGGCRNY + F TNPQ ++ L E D T +++L Q
Sbjct: 363 HKWTVSVNEGRWVRGCSAGGCRNYPDTFWTNPQYRLRLLEEDDDPEDDEVACTFVVALMQ 422
Query: 272 HSIMEPK-------VIGFSVYKMPKFLTETANQM---FFKRIKSTINSQ-YTNSRQVSQR 320
+ + + IGFS+Y++PK + M FF + S+ Y N R+V+QR
Sbjct: 423 KNRRKERKLGANLLTIGFSIYEVPKEMHGNKQHMQKEFFMSTTAKARSRAYINLREVTQR 482
Query: 321 CQLESGAYLIMPTTFEPREEAQFTLRIYSNKPLKMKVLDDPPQMTKAALVKAPPGSDSNG 380
+L G Y+I+P+++EP +E +F LR++S K + +++ + A G +S
Sbjct: 483 FRLSPGEYVIIPSSYEPHQEGEFILRVFSEKRNTSEEIENRIEADHPVPSPASTGEESEE 542
Query: 381 FFQYETLFLQLA 392
Q+ ++F +A
Sbjct: 543 DQQFLSIFQHIA 554
Score = 42.7 bits (96), Expect = 0.022
Identities = 20/58 (34%), Positives = 32/58 (55%), Gaps = 4/58 (6%)
Query: 11 VGDKWLVSCLGVLYLCKGLFYRVVPADQRMDTSYAGVFRLHGSYEALKYGSLLDGLAD 68
+GD WL++ + L L L YRV+P +Q YAG+F ++ +YG +D + D
Sbjct: 107 LGDCWLLAAIACLTLNDKLLYRVIPQEQSFSEQYAGIFH----FQFWRYGDWVDVVVD 160
Score = 35.9 bits (79), Expect = 2.5
Identities = 16/70 (22%), Positives = 35/70 (50%)
Query: 425 LKHLQLVFKTHAREKMGVLRVERLRDALKDVGFIVPERVISLLVFRYMRKDGMLRFGDFV 484
+K Q +FK + + + +R+A+ D GF + ++ ++ RY + + F F+
Sbjct: 628 IKQWQEIFKRYDFDHNDTISSYEMRNAINDAGFRLNNQLYDIITMRYANESMNVDFESFI 687
Query: 485 SAVMHLHRVF 494
S ++ L +F
Sbjct: 688 SCLVRLEGMF 697
>UniRef50_Q5C3R6 Cluster: SJCHGC08992 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC08992 protein - Schistosoma
japonicum (Blood fluke)
Length = 404
Score = 147 bits (357), Expect = 5e-34
Identities = 108/375 (28%), Positives = 177/375 (47%), Gaps = 50/375 (13%)
Query: 170 WKTIPQYERDRL-MTASKG--VWMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQ---- 222
W++IP ER R+ +T + WM F DF R F R+E+ HL E+ S + +
Sbjct: 2 WRSIPPDERKRIGLTFDEDGEFWMSFDDFVRYFSRLELCHLGPESVAVSPSATGSRYATR 61
Query: 223 KWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPD--------TVIISLNQHSI 274
+W++ +G W R +AGGC N+ N F+ NPQ + + +PD T+++ L Q +
Sbjct: 62 RWKITCEEGEWLRNSTAGGCTNFPNTFYMNPQFHVQIVDPDESDDDGTGTLVVGLMQKGL 121
Query: 275 ----MEPKVIGFSVYKMPKFLT--ETANQMFFKRIKSTINSQ-YTNSRQVSQRCQLESGA 327
+EP VIG+SV++MP + ++ FF S S + N R+V R +L G
Sbjct: 122 REKHIEPHVIGYSVFRMPSSAQNDQLLDRRFFMTNSSVARSPVFINMREVCGRHKLRPGH 181
Query: 328 YLIMPTTFEPREEAQFTLRIYSNKPLKMKVLDDPPQMTKAALVKAP-PGSDSNGFFQYET 386
Y+I+P TF P EEA+F LRI+S + LDD Q++ L P +D + E
Sbjct: 182 YVIVPCTFNPNEEAKFILRIFSERACDSNELDDVTQISITNLPDQPIKAADDKLIEKLEI 241
Query: 387 LFLQLADAHRTIDIFELQELLDACLPNDYIKSCVSIDTLKHLQL---------------- 430
+F ++A A I +LQ++L+ D+ S +T + +
Sbjct: 242 VFNRIAGASGAITYTQLQDILNEAFTKDFPFDGFSRETARSMMALMDADLSGGLGFGEFK 301
Query: 431 -------VFKTHARE----KMGVLRVERLRDALKDVGFIVPERVISLLVFRYMRKDGMLR 479
V+KT ++ G L LR+ ++ +GF V + + RY + G +
Sbjct: 302 KLWMELRVWKTIFKKFDEGHTGSLEAFELRNVMRTIGFHVSNMIYKAIACRYANEKGRIS 361
Query: 480 FGDFVSAVMHLHRVF 494
F D++ ++ L VF
Sbjct: 362 FDDYILLLVRLSTVF 376
>UniRef50_A7S7W7 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 678
Score = 145 bits (352), Expect = 2e-33
Identities = 140/506 (27%), Positives = 222/506 (43%), Gaps = 80/506 (15%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVMPE---------LSDGSALRTLLDTSSVVT 99
+L+GSYE+LK G + L D TGG+ ES + + + L+ S
Sbjct: 159 KLNGSYESLKGGQTGEALEDFTGGLAESFDLNKNVPKDLFCIMQTAEKRHALMGCSIAAK 218
Query: 100 AHYFPPVTIISVF--FLSLPTGIRLVKIRLRRSVINIFQVDTTNEPVYLIRLRRPLGHGE 157
A+ + TG R VK + RR ++ V L+R+R P G+
Sbjct: 219 ANEIEAKLNNGLVKGHAYTVTGCRQVKAKTRRGDLD----------VELVRVRNPWGNER 268
Query: 158 TPISHIVLDTALWKTIPQYERDRLMTASKG---VWMLFSDFQRLFPRIEMVHLDTETSRA 214
++ W+ + YE+ + + WM F DF++ F +E+ L +++
Sbjct: 269 EWKGAWGDGSSEWQLLSDYEKKSIGLTFEDDGEFWMSFDDFKKHFTTLEICMLGADSAME 328
Query: 215 ELSLSEKQKWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPD-------TVII 267
S+ ++ + G W+RG++AGGCRN++ FH NPQ +I L + D TVII
Sbjct: 329 GSSVG----FESRSEHGMWRRGLTAGGCRNFIKTFHKNPQFRITLQDSDDDADDLCTVII 384
Query: 268 SLNQ--------HSIMEPKVIGFSVYKMPKFLTETAN--QMFFKRIKSTINSQ-YTNSRQ 316
+L Q H I P IGFS+YK+ + + N FF+ ST S + NSR+
Sbjct: 385 ALMQKDRRKEKKHGI-NPLTIGFSIYKLEEEKDKQGNLDMEFFQYHASTARSPVFINSRE 443
Query: 317 VSQRCQLESGAYLIMPTTFEPREEAQFTLRIYSNKPLKMKVLDD----PPQMTKAALVKA 372
V R L G Y+++PTTF P EE F LR+YS K K +D+ PQ + +
Sbjct: 444 VVGRYALPPGEYVVIPTTFNPNEEGNFVLRMYSEKAHKTCEVDEKTEFAPQHQRRVQISR 503
Query: 373 PPGSDSNGFFQYETLFLQLADAHRTIDIFELQELLDACLPNDYIKSCVSIDTLKHLQLVF 432
N +++ F L+ ID ELQ++L L ND S++ + + ++
Sbjct: 504 EQHDTLNS--KFKEFFDNLSGRDGEIDAKELQQILSTALKNDLGGKPFSLEGARSIISMY 561
Query: 433 KTHAREKMGV-------LRVER--------------------LRDALKDVGFIVPERVIS 465
A K+G L+V++ LR ALK+ GF + V+
Sbjct: 562 DEDASGKLGFEEFKETWLQVKKWMKIFQVFDEDKSGEMDTYELRGALKEAGFTLSNSVLY 621
Query: 466 LLVFRYMRKDGMLRFGDFVSAVMHLH 491
+ RY DG + DF+ + L+
Sbjct: 622 AVSARYSTGDGKVNVDDFMEILTRLN 647
>UniRef50_P20807-2 Cluster: Isoform II of P20807 ; n=24;
Tetrapoda|Rep: Isoform II of P20807 - Homo sapiens
(Human)
Length = 729
Score = 144 bits (350), Expect = 4e-33
Identities = 132/507 (26%), Positives = 233/507 (45%), Gaps = 65/507 (12%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVMPELSDG--SALRTLLDTSSVVTAHYFPPV 106
+LHGSYEALK G+ + + D TGG+ E + + ++ ++ S++
Sbjct: 211 KLHGSYEALKGGNTTEAMEDFTGGVAEFFEIRDAPSDMYKIMKKAIERGSLMGCSID--- 267
Query: 107 TIISVFFLSLPTGIRLVKIRLRRSVINIFQVDTTNEPVYLIRLRRPLGHGETPISHIVLD 166
TII V + LV+ SV + +V E V L+RLR P G E S
Sbjct: 268 TIIPVQY-ETRMACGLVRGHAY-SVTGLDEVPFKGEKVKLVRLRNPWGQVEWNGSWSDRW 325
Query: 167 TALWKTIPQYERDRL---MTASKGVWMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQK 223
W + + E+ RL +T WM + DF F ++E+ +L + +++ + Q
Sbjct: 326 KD-WSFVDKDEKARLQHQVTEDGEFWMSYEDFIYHFTKLEICNLTADALQSD----KLQT 380
Query: 224 WQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPD----------TVIISLNQHS 273
W + +++G W RG SAGGCRN+ + F TNPQ ++ L E D + +++L Q +
Sbjct: 381 WTVSVNEGRWVRGCSAGGCRNFPDTFWTNPQYRLKLLEEDDDPDDSEVICSFLVALMQKN 440
Query: 274 IMEPK-------VIGFSVYKMPKFLTETANQM---FFKRIKSTINSQ-YTNSRQVSQRCQ 322
+ + IGF++Y++PK + + FF S S+ Y N R+VSQR +
Sbjct: 441 RRKDRKLGASLFTIGFAIYEVPKEMHGNKQHLQKDFFLYNASKARSKTYINMREVSQRFR 500
Query: 323 LESGAYLIMPTTFEPREEAQFTLRIYSNKPLKMKVLDDPPQMTKAALVKAPPGSDSNGFF 382
L Y+I+P+T+EP +E +F LR++S K + +++ + + +S
Sbjct: 501 LPPSEYVIVPSTYEPHQEGEFILRVFSEKRNLSEEVENTISVDRPVPQPGSSDQESEEQQ 560
Query: 383 QYETLFLQLADAHRTIDIFELQELLDACLPND--------YIKSCVS----IDT------ 424
Q+ +F Q+A I EL+++L+ + ++SC S +DT
Sbjct: 561 QFRNIFKQIAGDDMEICADELKKVLNTVVNKHKDLKTHGFTLESCRSMIALMDTDGSGKL 620
Query: 425 -----------LKHLQLVFKTHAREKMGVLRVERLRDALKDVGFIVPERVISLLVFRYMR 473
+K Q +FK + ++ G + +R+A+ D GF + ++ ++ RY
Sbjct: 621 NLQEFHHLWNKIKAWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDIITMRYAD 680
Query: 474 KDGMLRFGDFVSAVMHLHRVFVQVYDF 500
K + F F+ + L +F + F
Sbjct: 681 KHMNIDFDSFICCFVRLEGMFRAFHAF 707
Score = 40.3 bits (90), Expect = 0.12
Identities = 19/58 (32%), Positives = 33/58 (56%), Gaps = 4/58 (6%)
Query: 11 VGDKWLVSCLGVLYLCKGLFYRVVPADQRMDTSYAGVFRLHGSYEALKYGSLLDGLAD 68
+GD W ++ + L L + L +RV+P DQ +YAG+F ++ +YG +D + D
Sbjct: 126 LGDCWFLAAIACLTLNQHLLFRVIPHDQSFIENYAGIFH----FQFWRYGEWVDVVID 179
>UniRef50_UPI0000ECB984 Cluster: Calpain-3 (EC 3.4.22.54) (Calpain
L3) (Calpain p94) (Calcium-activated neutral proteinase
3) (CANP 3) (Muscle-specific calcium-activated neutral
protease 3).; n=1; Gallus gallus|Rep: Calpain-3 (EC
3.4.22.54) (Calpain L3) (Calpain p94) (Calcium-activated
neutral proteinase 3) (CANP 3) (Muscle-specific
calcium-activated neutral protease 3). - Gallus gallus
Length = 727
Score = 142 bits (343), Expect = 3e-32
Identities = 116/426 (27%), Positives = 201/426 (47%), Gaps = 62/426 (14%)
Query: 130 SVINIFQVDTTNEPVYLIRLRRPLGHGET--PISHIVLDTALWKTIPQYERDRLM--TAS 185
SV + + E + L+RLR P G E P S + W I + E+ RL A
Sbjct: 287 SVTAVEETTYKGEKMRLVRLRNPWGQVEWNGPWSD---KSEEWNFIDEEEKTRLQHKIAE 343
Query: 186 KG-VWMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQKWQMKMHQGGWKRGVSAGGCRN 244
G W+ F DF R F ++E+ +L +T A+ + Q W + +++G W RG SAGGCRN
Sbjct: 344 DGEFWISFEDFMRHFTKLEICNLTPDTLEAD----KLQTWTVSVNEGRWVRGCSAGGCRN 399
Query: 245 YVNFFHTNPQVQIMLNEPD----------TVIISLNQHSIMEPK-------VIGFSVYKM 287
Y + F TNPQ ++ L E D + +++L Q + + + IGF++Y++
Sbjct: 400 YPDTFWTNPQYRLKLLEEDDDPEDEEVICSFLVALMQKNRRKERKLGANLYTIGFAIYEV 459
Query: 288 PKFLTETANQM---FFKRIKSTINSQ-YTNSRQVSQRCQLESGAYLIMPTTFEPREEAQF 343
PK + T + + FF S S+ Y N R++S+R +L Y+I+P+T+EP +E +F
Sbjct: 460 PKEMHGTKHHLQKDFFLYNASKARSKTYINMREISERFRLPPSEYVIIPSTYEPHQEGEF 519
Query: 344 TLRIYSNKPLKMKVLDDPPQMTKAALVKAPPGSDSNGFFQYETLFLQLADAHRTIDIFEL 403
LR++S K + +++ + + + A S Q+ +F Q+A I+ EL
Sbjct: 520 ILRVFSEKRSLSEEVENMIEADRPSRSSAKAREKSEEETQFRNIFRQIAGDDMEINAEEL 579
Query: 404 QELL--------DACLPNDYIKSC--------------VSIDTLKHL-------QLVFKT 434
+ +L D ++SC ++ D +HL Q +FK
Sbjct: 580 RNVLNNVVKKHKDLKTEGFELESCRSMIALMDTDGSGKINFDEFRHLWDKIKSWQKIFKH 639
Query: 435 HAREKMGVLRVERLRDALKDVGFIVPERVISLLVFRYMRKDGMLRFGDFVSAVMHLHRVF 494
+ + G + +R+A+KD GF + ++ ++ RY K+ + F F+ + L +F
Sbjct: 640 YDADHSGTINSYEMRNAVKDAGFRLNNQLYDIITMRYADKNMNIDFDSFICCFVRLDAMF 699
Query: 495 VQVYDF 500
+ F
Sbjct: 700 RAFHAF 705
Score = 40.3 bits (90), Expect = 0.12
Identities = 20/58 (34%), Positives = 32/58 (55%), Gaps = 4/58 (6%)
Query: 11 VGDKWLVSCLGVLYLCKGLFYRVVPADQRMDTSYAGVFRLHGSYEALKYGSLLDGLAD 68
+GD W ++ + L L K L RV+P DQ +YAG+F ++ +YG +D + D
Sbjct: 77 LGDCWFLAAIACLTLNKKLLCRVIPHDQSFIQNYAGIFH----FQFWRYGDWVDVIID 130
Score = 40.3 bits (90), Expect = 0.12
Identities = 16/27 (59%), Positives = 21/27 (77%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITE 75
+LHGSYEALK G+ + + D TGG+TE
Sbjct: 162 KLHGSYEALKGGNTTEAMEDFTGGVTE 188
>UniRef50_Q9UMQ6 Cluster: Calpain-11; n=214; Euteleostomi|Rep:
Calpain-11 - Homo sapiens (Human)
Length = 702
Score = 133 bits (321), Expect = 1e-29
Identities = 118/390 (30%), Positives = 186/390 (47%), Gaps = 44/390 (11%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVM--PELSDGSALRTLLDTSSVVTAHYFPPV 106
+L GSYEAL GS ++GL D TGG+ +S + P + LR ++ SS++ +
Sbjct: 184 KLSGSYEALSGGSTMEGLEDFTGGVAQSFQLQRPPQNLLRLLRKAVERSSLMGCS----I 239
Query: 107 TIISVFFLSLPTGIRLVKIRLRRSVINIFQVDTTNEPVYLIRLRRPLGHGETPISHIVLD 166
+ S L T LV+ SV + V + LIR+R P G E + D
Sbjct: 240 EVTSDSELESMTDKMLVRGHAY-SVTGLQDVHYRGKMETLIRVRNPWGRIEW--NGAWSD 296
Query: 167 TAL-WKTIPQYERDRLM--TASKGVWMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQK 223
+A W+ + + +L+ T WM + DF F +E+ +L +T LS K
Sbjct: 297 SAREWEEVASDIQMQLLHKTEDGEFWMSYQDFLNNFTLLEICNLTPDT----LSGDYKSY 352
Query: 224 WQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPD-------------TVIISLN 270
W ++G W+RG SAGGCRN+ F TNPQ +I L E D T +++L
Sbjct: 353 WHTTFYEGSWRRGSSAGGCRNHPGTFWTNPQFKISLPEGDDPEDDAEGNVVVCTCLVALM 412
Query: 271 Q----HSIMEP---KVIGFSVYKMPKFL-----TETANQMFFKRIKSTINSQYTNSRQVS 318
Q H+ + + IGF +Y +PK + F K + +TNSR+VS
Sbjct: 413 QKNWRHARQQGAQLQTIGFVLYAVPKEFQNIQDVHLKKEFFTKYQDHGFSEIFTNSREVS 472
Query: 319 QRCQLESGAYLIMPTTFEPREEAQFTLRIYSNKPLKMKVLDDPPQMTKAALVKAPPGSDS 378
+ +L G Y+I+P+TFEP +A F LR+++ K + LD ++ A ++ S+
Sbjct: 473 SQLRLPPGEYIIIPSTFEPHRDADFLLRVFTEKHSESWELD---EVNYAEQLQEEKVSED 529
Query: 379 NGFFQYETLFLQLADAHRTIDIFELQELLD 408
+ + LF +A + I ++ELQ LL+
Sbjct: 530 DMDQDFLHLFKIVAGEGKEIGVYELQRLLN 559
Score = 43.6 bits (98), Expect = 0.013
Identities = 18/38 (47%), Positives = 24/38 (63%)
Query: 11 VGDKWLVSCLGVLYLCKGLFYRVVPADQRMDTSYAGVF 48
+GD WL++ +G L C L YRVVP Q +YAG+F
Sbjct: 99 LGDCWLLAAIGSLTTCPKLLYRVVPRGQSFKKNYAGIF 136
>UniRef50_Q17E36 Cluster: Calpain, putative; n=2; Culicidae|Rep:
Calpain, putative - Aedes aegypti (Yellowfever mosquito)
Length = 751
Score = 132 bits (318), Expect = 3e-29
Identities = 118/384 (30%), Positives = 179/384 (46%), Gaps = 38/384 (9%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVM-----PELSDGSALRTLLDTSSVVTAHYF 103
+LHG YEAL G+ + + D TGGITES + P + + T S+ +
Sbjct: 204 KLHGCYEALNSGTAREAMQDFTGGITESYRLRGKEPPPDNLFEIIHTGFQRGSMFACNIL 263
Query: 104 PPVTIISVFFLSLPTGIRLVKIRLRRSVINIFQVDTTNEPVYLIRLRRPLGHGETPISHI 163
P I P G L+K SV + + TT LIRLR P G G
Sbjct: 264 PDPKIPEAH---TPQG--LLKGH-SYSVTKTYTMGTTK----LIRLRNPWGDGIEWNGAW 313
Query: 164 VLDTALWKTIPQYERDRL-MTASKG--VWMLFSDFQRLFPRIEMVHLDTETSRAELSLSE 220
+ W+ IP+ +R +L +T WM F DF R F R+E+ +L + + + +
Sbjct: 314 SDRSQEWQAIPKAQRKQLGLTIDNDGEFWMDFEDFLRYFDRVEICNLSPDP--LDDTEAS 371
Query: 221 KQKWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPD--------TVIISLNQH 272
K+ WQ+ G W +G ++GGC +Y+ F TNPQ I L++PD T++++L Q
Sbjct: 372 KRGWQVSTIDGEWVKGSTSGGCIDYMESFWTNPQYVIHLDKPDSDDPSGMCTIVVALMQK 431
Query: 273 ----SIMEPKVIGFSVYKMPK--FLTETANQMFFKR--IKSTINSQYTNSRQVSQRCQLE 324
+ IGF +Y++ + + FFK+ + S Y NSR+VS R +L
Sbjct: 432 FRRAEDLPSLTIGFVIYRVTEEHLRNKPVPMKFFKKNDYRIVARSIYINSREVSCRLRLN 491
Query: 325 SGAYLIMPTTFEPREEAQFTLRIYSNKPLKMKVLDDPPQM-TKAALVKAPPGSDSNGFFQ 383
G YL++PTT P EE +F +RI+S ++ D T V P D + + +
Sbjct: 492 PGIYLVVPTTLHPIEEGEFLIRIFSELRNCLEENDCTVCFGTMDDRVSGPLQEDED-WPK 550
Query: 384 YETLFLQLADAHRTIDIFELQELL 407
F +LAD +TID L +L
Sbjct: 551 MVRHFYELADRKKTIDHIALGAIL 574
>UniRef50_Q4SVI4 Cluster: Chromosome 18 SCAF13757, whole genome
shotgun sequence; n=3; Tetraodontidae|Rep: Chromosome 18
SCAF13757, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 701
Score = 131 bits (317), Expect = 4e-29
Identities = 125/419 (29%), Positives = 200/419 (47%), Gaps = 69/419 (16%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVMPELSDG--SALRTLLDTSSVVTAHYFPPV 106
+LHGSYE+LK GS L+ + D TGG+ E + S ++ LD S++ +
Sbjct: 185 KLHGSYESLKGGSTLEAMEDFTGGVGELYETKKAPGDLFSIMKKALDRGSMMGCSI--DI 242
Query: 107 TIISVFFLSLPTGIRLVKIRLRRSVINIFQVDTTNEPVYLIRLRRPLGHGET--PISH-- 162
T + L G LVK S+ + +V+ V LIR+R P G E P S
Sbjct: 243 TSSAESEAKLNNG--LVKGHAY-SITGMEEVNYRGGTVQLIRIRNPWGQVEWNGPWSDKY 299
Query: 163 ------IVLDTALWKTIPQYERDRLM---TASKGVWMLFSDFQRLFPRIEMVHLDTETSR 213
+ + W + E+ R++ T WM F DF+ + R+E+ ++ +
Sbjct: 300 DFFFFFLQPSSREWNYVDAAEKRRILQNSTEDGEFWMEFEDFKANYDRVEICNMTPDA-- 357
Query: 214 AELSLSEKQKWQMKMHQGGWKRGVSAGGCRNYVNF----------------------FHT 251
L+ S K+ W++ + +G W RG +AGGCRNY+ F T
Sbjct: 358 --LTESTKRHWEVNLFEGSWIRGSTAGGCRNYIGHKVMMKVTLRCPLIPLNLQSADTFWT 415
Query: 252 NPQVQIMLNEPD-------TVIISLNQHSI-------MEPKVIGFSVYKMPKFLTETANQ 297
NPQ ++ L + D +V+I+L Q + ++ + IGF+VY+ P+ + A++
Sbjct: 416 NPQFKLKLEDADDDDDDVCSVVIALMQKNRRKLRKEGLDMETIGFAVYEAPEH-EDQASK 474
Query: 298 MFFKRIKSTINSQ-YTNSRQVSQRCQLESGAYLIMPTTFEPREEAQFTLRIYSNKPLKMK 356
FF+ S S+ Y N+R+VS+R L G YL++PTTF+P EA F +R++S K K
Sbjct: 475 DFFRYHASKARSRTYINTREVSERFTLPPGEYLLVPTTFQPHHEADFLVRMFSEK--KAG 532
Query: 357 VLDDPPQMTKAALVKAPPGS----DSNGFFQYETLFLQLADAHRTIDIFELQELLDACL 411
+ + A L + PP S +S+ LF QLA + I + ELQ++L+ L
Sbjct: 533 AV-EMGSTVDADLPEPPPPSLPEEESDEEKGLRRLFDQLAGEDKAISVRELQQMLNGVL 590
Score = 38.3 bits (85), Expect = 0.48
Identities = 16/37 (43%), Positives = 22/37 (59%)
Query: 12 GDKWLVSCLGVLYLCKGLFYRVVPADQRMDTSYAGVF 48
GD WL++ + L L K +V+P DQ D YAG+F
Sbjct: 101 GDCWLLAAIASLTLKKDALAQVIPRDQEFDRRYAGIF 137
>UniRef50_UPI00006A0B93 Cluster: Calpain-12 (EC 3.4.22.-).; n=3;
Xenopus tropicalis|Rep: Calpain-12 (EC 3.4.22.-). -
Xenopus tropicalis
Length = 668
Score = 131 bits (316), Expect = 5e-29
Identities = 95/324 (29%), Positives = 159/324 (49%), Gaps = 29/324 (8%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVMPELSDGSALRTLLDTSSVVTAHYFPPVTI 108
+L+GSYEAL G + + D TGG+ E++ + L L++ + + + I
Sbjct: 161 KLNGSYEALNGGFMNEAFVDFTGGLDETVDLKVPPPN--LYHLIEKAVKKRSLMGASIQI 218
Query: 109 ISVFFLSLPTGIRLVKIRLRRSVINIFQVDTTNEPVYLIRLRRPLGHGETPISHIVLDTA 168
S + L T LVK S+I ++++ ++L+RLR P G E ++
Sbjct: 219 QSQYERELTTPEGLVKGHAY-SIIATWKMEQNGRTIHLLRLRNPWGKVEWN-GRWSDNSP 276
Query: 169 LWKTIPQYERDRLMTASKG--VWMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQKWQM 226
LW + R+++ + WM DF R F +E+ +L E+ + + + W
Sbjct: 277 LWSQVTFELREKMQVRGEDGEFWMQMEDFLRFFDILEVCNLTPESMKDKCA----HLWNT 332
Query: 227 KMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPD-------TVIISLNQHSIMEPK- 278
G W G +AGGCRNY F TNPQ + L E D T+++SL Q + + +
Sbjct: 333 NTFSGRWMMGHNAGGCRNYRATFWTNPQYIVTLTEEDEDSSDGCTLLVSLMQKNRRQYRS 392
Query: 279 ------VIGFSVYKMPKFLTETANQMFFKRIKSTINS-----QYTNSRQVSQRCQLESGA 327
V+GF +Y++PK +T+ +Q K + INS + R V++R QL G
Sbjct: 393 RGQDFLVVGFEIYQVPKEVTQHISQTLKKLSLTQINSVLQSIPFVAKRDVTERYQLPPGR 452
Query: 328 YLIMPTTFEPREEAQFTLRIYSNK 351
YL++P+TF+P +E+ F LR+++ K
Sbjct: 453 YLLIPSTFQPHQESDFILRVFTEK 476
>UniRef50_Q17E35 Cluster: Calpain, putative; n=3; Culicidae|Rep:
Calpain, putative - Aedes aegypti (Yellowfever mosquito)
Length = 799
Score = 131 bits (316), Expect = 5e-29
Identities = 113/406 (27%), Positives = 179/406 (44%), Gaps = 30/406 (7%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVMPEL-SDGSALRTLLDTSSVVTAHYFPPVT 107
+L GSYEAL+ GS + + D TGGI ES M ++ D + S + A P
Sbjct: 206 KLFGSYEALRGGSASEAMVDFTGGIAESYEMKDVPKDLFQIIEKGFRSHAMFACSLEPDP 265
Query: 108 IISVFFLSLPTG-IRLVKIRLRRSVINIFQVDTTNEPVYLIRLRRPLGHGETPISHIVLD 166
P G IR L + + Q + L+RLR P G+
Sbjct: 266 YKPE--AETPQGLIRGHAYSLTMAKMVDIQTPNVKGKIPLLRLRNPWGNANEWNGAWSDK 323
Query: 167 TALWKTIPQYERDRL---MTASKGVWMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQK 223
+ WK IP+ + + WM + DF + F RIEM ++ + + S
Sbjct: 324 SPEWKYIPEETKREIGLIFELDGEFWMSYQDFVKYFDRIEMCNMSPDCPI--IRQSGNYP 381
Query: 224 WQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPD--------TVIISLNQHSI- 274
W+ +G W G +AGGCRNY + F NPQ + L EPD T II+L Q +
Sbjct: 382 WKQSSFEGEWVIGSTAGGCRNYPDTFWHNPQYVVHLKEPDKDDAEGKATAIIALLQKNRR 441
Query: 275 ------MEPKVIGFSVYKMPK--FLTETANQMFFKRIKSTINSQYTNSRQVSQRCQLESG 326
M+ +G +Y++ + + + + FF R S S + N R+V+ R +++ G
Sbjct: 442 SKRNKGMDCLTVGLIIYRVTERDLIRKPLPKEFFLRNASIARSTFVNLREVTCRFRMDPG 501
Query: 327 AYLIMPTTFEPREEAQFTLRIYSNKPLKMKVLDD---PPQMTKAALVKAPPGSDSNGFFQ 383
Y+++P+TFEP E +F +R++S P M +D + +K P + + Q
Sbjct: 502 TYVVVPSTFEPNVEGEFMIRVFSECPDCMTENEDCVGECDLDPRIKMKVPDPTKPDPQRQ 561
Query: 384 -YETLFLQLADAHRTIDIFELQELLDACLPNDYIKSCVSIDTLKHL 428
E LFL +A +D EL+ +LD C +D + + H+
Sbjct: 562 AMEKLFLDVAGVDGEVDWMELKLVLDHCFRDDIAIAAKGVSRSYHV 607
Score = 39.1 bits (87), Expect = 0.27
Identities = 17/60 (28%), Positives = 35/60 (58%)
Query: 431 VFKTHAREKMGVLRVERLRDALKDVGFIVPERVISLLVFRYMRKDGMLRFGDFVSAVMHL 490
VFK + ++ G L LR AL+ G+ + ++++ L+ RY ++G + F DF++ + +
Sbjct: 710 VFKLYDTDRSGHLNPFELRAALQSAGYHLNSKILNSLMHRYGSREGEIWFDDFITCAVKI 769
>UniRef50_Q4SDQ1 Cluster: Chromosome 10 SCAF14634, whole genome
shotgun sequence; n=5; Euteleostomi|Rep: Chromosome 10
SCAF14634, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 844
Score = 127 bits (306), Expect = 8e-28
Identities = 105/349 (30%), Positives = 164/349 (46%), Gaps = 52/349 (14%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVMPELSDG--SALRTLLDTSSVVTAHYFPPV 106
+LHGSYEALK G+ + + D TGG+TE M E ++ LD S++ V
Sbjct: 192 KLHGSYEALKGGNTTEAMEDFTGGVTEFYEMKEAPKELYKIMKKALDRGSLMGCSIDSLV 251
Query: 107 TIISVFFLSLPTGIRLVKIRLRRSVINIFQVDTTNEPVYLIRLRRPLGHGE--------- 157
+ F TG+ +V V L+RLR P G E
Sbjct: 252 P--ARFETRTATGLVKGHAYSVTAVEECKPSQHKESKVRLVRLRNPWGQVEWNGPWSDKN 309
Query: 158 TPISHIVLDTALWKTIPQYERDRL--MTASKG-VWMLFSDFQRLFPRIEMVHLDTETSRA 214
P + + W T+ + E+++L +A G WM F DF++ + +IE+ +L +
Sbjct: 310 RPFRLLRNSSKEWSTLSKAEKEKLHHQSAEDGEFWMSFEDFKKNYTKIEICNLTPDA--- 366
Query: 215 ELSLSEKQKWQMKMHQGGWKRGVSAGGCRNY-----------VNFFHTNPQVQIMLNEPD 263
L + KW + +++G W RG SAGGCRNY + F TNPQ ++ L E D
Sbjct: 367 -LEDDKIHKWTVSVNEGRWVRGCSAGGCRNYPEGEEMLLKCPADTFWTNPQYRLRLLEED 425
Query: 264 ----------TVIISLNQHSIMEPK-------VIGFSVYKMPKFLTETANQM---FFKRI 303
T +++L Q + + + IGF++Y++PK + M FF
Sbjct: 426 DDPEENEVGCTFVVALMQKNRRKERKMGANLFTIGFAIYEVPKEMHGNKQHMQKDFFLYS 485
Query: 304 KSTINSQ-YTNSRQVSQRCQLESGAYLIMPTTFEPREEAQFTLRIYSNK 351
S + Y N R+V+QR +L G Y+I+P+T+EP +E +F LR++S K
Sbjct: 486 SSKARCKSYINLREVTQRFRLSPGEYVIVPSTYEPHQEGEFILRVFSEK 534
Score = 45.2 bits (102), Expect = 0.004
Identities = 22/58 (37%), Positives = 34/58 (58%), Gaps = 4/58 (6%)
Query: 11 VGDKWLVSCLGVLYLCKGLFYRVVPADQRMDTSYAGVFRLHGSYEALKYGSLLDGLAD 68
+GD WL++ + L L + L YRVVP +Q SYAG+F ++ +YG +D + D
Sbjct: 107 LGDCWLLAAIACLTLNEKLLYRVVPPEQSFSESYAGIFH----FQFWRYGDWVDVVID 160
>UniRef50_P27730 Cluster: Calpain; n=9; Schistosoma|Rep: Calpain -
Schistosoma mansoni (Blood fluke)
Length = 758
Score = 127 bits (306), Expect = 8e-28
Identities = 126/496 (25%), Positives = 215/496 (43%), Gaps = 54/496 (10%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVMPELSDGSALRTLLDTSSVVTAHYFPPVTI 108
+L+G Y L GS + + DLTGGI S+ EL+ L+D +
Sbjct: 239 KLNGCYAHLSGGSQSEAMEDLTGGICLSL---ELNQKERPSDLIDQLKIYAQRCCLMGCS 295
Query: 109 ISVFFLSLPTGIRLVKIRLRRSVINIFQVDTTNEPVYLIRLRRPLGHGETPISHIVLDTA 168
I + L+ S+ ++ V+ +L+RLR P G +
Sbjct: 296 IDSSVMEQKMDNGLIGSHAY-SLTGVYPVNYRGRTQWLMRLRNPWGDSHEWKGAWCDGSP 354
Query: 169 LWKTIPQYERDRL---MTASKGVWMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQKWQ 225
W+ I + E+ + TA WM + DF F R+E+ HL E+ + K++
Sbjct: 355 QWREISEQEKKNINLSFTADGEFWMSYEDFVTCFSRVEVCHLGLESLEYNQNFHGKRRLD 414
Query: 226 MKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPD--------TVIISLNQHSIMEP 277
+ G W+R V+AGGC N + T+PQ +I + +PD +V+I L Q I +
Sbjct: 415 EAIFSGQWQRNVNAGGCINNRTTYWTSPQFRITVEDPDPDDDDNKCSVLIGLMQTDIRKK 474
Query: 278 -----KVIGFSVYKMPKFLTETANQMFFKRIKSTINSQYTNSRQVSQRCQLESGAYLIMP 332
+ IGF VY P L ++ SQ+ N+R+V+ + ++ G+Y+++P
Sbjct: 475 VGADFQPIGFMVYNAPDDLNTLLSRAQLLTRSPIAKSQFINTREVTAQFRVPPGSYVVIP 534
Query: 333 TTFEPREEAQFTLRIYSNKPLKMKVLDD--PPQMTKAALVKAPPGSDS--NGFFQYETLF 388
+TF+P E F LR++S + + LD+ Q +++A D+ + + E F
Sbjct: 535 STFDPNIEVNFILRVFSQTSITEQELDEDNTNQGLPDDVIEALKLEDTLLDEDQEIEQKF 594
Query: 389 LQLADAH-RTIDIFELQELLDAC----LPN------DYIKSCV-SIDT--LKHLQL---- 430
L + D I+ +L ELL+ +PN + +S V S+D H++L
Sbjct: 595 LAIRDPKTNAINAVKLGELLNNSTLQDIPNFQGFNKELCRSMVASVDNNLTGHVELNEFM 654
Query: 431 -----------VFKTHAREKMGVLRVERLRDALKDVGFIVPERVISLLVFRYMRK-DGML 478
+F H ++ G R+AL D G+ V R+I+ ++ RY +
Sbjct: 655 DLWIQAKGWKHIFIKHDVDQSGYFSAYEFREALNDAGYHVSNRLINAIINRYQDPGTDKI 714
Query: 479 RFGDFVSAVMHLHRVF 494
F DF+ ++ L F
Sbjct: 715 SFEDFMLCMVRLKTAF 730
>UniRef50_UPI000065EF2F Cluster: Homolog of Homo sapiens "Calpain 2,
large [catalytic] subunit precursor; n=1; Takifugu
rubripes|Rep: Homolog of Homo sapiens "Calpain 2, large
[catalytic] subunit precursor - Takifugu rubripes
Length = 724
Score = 124 bits (298), Expect = 7e-27
Identities = 111/348 (31%), Positives = 157/348 (45%), Gaps = 51/348 (14%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITES------------IVMPELSDGSALRTLLDTSS 96
+++G YEAL GS +G D TGGI+E I+ L GS L +D S
Sbjct: 170 KVNGCYEALSGGSTTEGFEDFTGGISERHDLGNADPHLFHIIKKALERGSLLGCSIDVSF 229
Query: 97 VVTAHYFP-------------PVTIISVFFLSLPTGIRLVKIRLRRSVINIFQVDTTNEP 143
+ + P I + T +LVK SV QV+ E
Sbjct: 230 SLFFYVLRSDAVGFNLTGSSWPRQITNASDSEAVTYRKLVKGHAY-SVTGADQVEYGGEA 288
Query: 144 VYLIRLRRPLGHGETPISHIVLDTALWKTIPQYERDRLMTASKG--VWMLFSDFQRLFPR 201
V+LIR+R P G E + D++ W+ + +R RL S WM FSDF R + R
Sbjct: 289 VHLIRIRNPWGQVEWNGAWSD-DSSEWRYVSSDDRARLTNRSDDGEFWMSFSDFLRQYSR 347
Query: 202 IEMVHLDTETSRAELSLSEKQKWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNE 261
+E+ +L + L+ + +KW + W+RG SAGGCRNY N F NPQ I L E
Sbjct: 348 LEICNLTPDA----LTGDDYKKWAETEFEDTWRRGSSAGGCRNYPNSFWMNPQFVIKLEE 403
Query: 262 PD----------TVIISLNQHSIM-------EPKVIGFSVYKMPKFLTETANQMFFKRIK 304
D T I+ L Q + + + IGF++Y+ + FF R
Sbjct: 404 VDDDPDEGQEGCTFIVGLMQKNRRRMRKMGEDMETIGFAIYECSGLRNVHLKRDFFLRNA 463
Query: 305 STINSQ-YTNSRQVSQRCQLESGAYLIMPTTFEPREEAQFTLRIYSNK 351
S S+ + N R+V L G YLI+P+TFEP + A F LR++S K
Sbjct: 464 SAARSETFINLREVCNHFCLPPGEYLIIPSTFEPNKNADFYLRVFSEK 511
Score = 41.9 bits (94), Expect = 0.039
Identities = 21/58 (36%), Positives = 34/58 (58%), Gaps = 4/58 (6%)
Query: 11 VGDKWLVSCLGVLYLCKGLFYRVVPADQRMDTSYAGVFRLHGSYEALKYGSLLDGLAD 68
+GD WL++ + L L K + RVVP DQ + +YAG+F +E ++G +D + D
Sbjct: 85 LGDCWLLAAIASLTLNKQVLSRVVPHDQSFEDNYAGIFH----FEFWQFGEWVDVVVD 138
>UniRef50_P34308 Cluster: Calpain clp-1; n=5; Caenorhabditis
elegans|Rep: Calpain clp-1 - Caenorhabditis elegans
Length = 780
Score = 122 bits (293), Expect = 3e-26
Identities = 89/324 (27%), Positives = 153/324 (47%), Gaps = 26/324 (8%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVMPELSDGSALRTLLDTSSVVTAHYFPPVTI 108
+L GSYEALK G+ + L D+TGG+TE I + + ++ ++ + +
Sbjct: 453 KLFGSYEALKGGTTSEALEDMTGGLTEFIDLKN-PPRNLMQMMMRGFEMGSLFGCSIEAD 511
Query: 109 ISVFFLSLPTGIRLVKIRLRRSVINIFQVDTTNEPVYLIRLRRPLGHGETPISHIVLDTA 168
+V+ + G LVK S+ VD N ++R+R P G+ + ++
Sbjct: 512 PNVWEAKMSNG--LVKGHAY-SITGCRIVDGPNGQTCILRIRNPWGNEQEWNGPWSDNSR 568
Query: 169 LWKTIPQYERDRL---MTASKGVWMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQK-- 223
W+++P + + WM F DF R F ++E+ +L + ++ +
Sbjct: 569 EWRSVPDSVKQDMGLKFDHDGEFWMSFDDFMRNFEKMEICNLGPDVMDEVYQMTGVKAAG 628
Query: 224 --WQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPD--------TVIISLNQ-- 271
W H G W R +AGGCRNY+N F NPQ ++ L + D TVI ++ Q
Sbjct: 629 MVWAANTHDGAWVRNQTAGGCRNYINTFANNPQFRVQLTDSDPDDDDELCTVIFAVLQKY 688
Query: 272 -----HSIMEPKVIGFSVYKMPKFLTETANQMFFKRIKSTINSQYTNSRQVSQRCQLESG 326
++ IGF+VY + Q F + ++ + N R+++ R ++ G
Sbjct: 689 RRNLKQDGLDNVPIGFAVYDAGNNRGRLSKQFFAANKSAMRSAAFINLREMTGRFRVPPG 748
Query: 327 AYLIMPTTFEPREEAQFTLRIYSN 350
Y+++P+TFEP EEA+F LR+Y+N
Sbjct: 749 NYVVVPSTFEPNEEAEFMLRVYTN 772
Score = 44.4 bits (100), Expect = 0.007
Identities = 23/58 (39%), Positives = 33/58 (56%), Gaps = 4/58 (6%)
Query: 11 VGDKWLVSCLGVLYLCKGLFYRVVPADQRMDTSYAGVFRLHGSYEALKYGSLLDGLAD 68
+GD WL++ L L LFYRVVP DQ +YAG+F ++ +YG +D + D
Sbjct: 368 LGDCWLLAAAANLTLKDELFYRVVPPDQSFTENYAGIFH----FQFWQYGKWVDVVID 421
>UniRef50_Q4T7L5 Cluster: Chromosome 14 SCAF8084, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 14 SCAF8084, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 470
Score = 121 bits (291), Expect = 5e-26
Identities = 70/183 (38%), Positives = 104/183 (56%), Gaps = 25/183 (13%)
Query: 190 MLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQKWQMKMHQGGWKRGVSAGGCRNYVNFF 249
M FSDFQR F ++EM +L +T + + E+ W + ++QG W RG SAGGCRNY + F
Sbjct: 1 MSFSDFQRNFTKLEMCNLTPDTLQGD----ERHSWTVSVNQGRWVRGSSAGGCRNYPDTF 56
Query: 250 HTNPQVQIMLNEPD----------TVIISLNQHSIMEPK-------VIGFSVYKMPKFL- 291
TNPQ ++ L E D T++++L Q + +GFS+YK+P+ +
Sbjct: 57 WTNPQYRLKLYEEDDDSEGGQRTCTIVVALMQKGRRMQRQQGPRFLTVGFSIYKVPQEMC 116
Query: 292 --TETANQMFFKRIKSTIN-SQYTNSRQVSQRCQLESGAYLIMPTTFEPREEAQFTLRIY 348
T+ + FF ST Y N R+V++R L G Y+I+PTTFEP +E +F LR++
Sbjct: 117 GQTQHLQKDFFLYTASTAKIKSYINLREVTERFHLPPGEYVIIPTTFEPHQEGEFILRVF 176
Query: 349 SNK 351
S K
Sbjct: 177 SEK 179
Score = 35.5 bits (78), Expect = 3.4
Identities = 15/66 (22%), Positives = 35/66 (53%)
Query: 429 QLVFKTHAREKMGVLRVERLRDALKDVGFIVPERVISLLVFRYMRKDGMLRFGDFVSAVM 488
QL+FK ++++K + +R+A+ D GF + ++ ++ RY + + F ++ +
Sbjct: 382 QLIFKRYSKDKTCSISSFEMRNAVNDAGFHLNNQLYDIIAMRYADERLNISFDSYICCFV 441
Query: 489 HLHRVF 494
L +F
Sbjct: 442 RLEGMF 447
>UniRef50_Q58EB1 Cluster: CAPN1 protein; n=10; Clupeocephala|Rep:
CAPN1 protein - Danio rerio (Zebrafish) (Brachydanio
rerio)
Length = 727
Score = 116 bits (280), Expect = 1e-24
Identities = 112/414 (27%), Positives = 182/414 (43%), Gaps = 60/414 (14%)
Query: 130 SVINIFQVDTTNEPVYLIRLRRPLGHGETPISHIVLDTALWKTIPQYERDRLMTASKG-V 188
+V ++QV + PV L+RL P G E ++ LW T+ +R +L+ + G
Sbjct: 293 TVTKVYQVMSGRNPVQLVRLFNPWGDSEWN-GDWSDNSPLWNTVDDEDRKQLLVSDNGEF 351
Query: 189 WMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQKWQMKMHQGGWKRGVSAGGCRNYVNF 248
WM DF R F +++ + + + KW K H G W G +AGGC N+ +
Sbjct: 352 WMSMKDFLRTFDNMDICCNCPDFLEGKSAC----KWTSKSHNGSWVPGSTAGGCMNHPDT 407
Query: 249 FHTNPQVQIMLNEPD--------TVIISLNQ------HSIMEPKVIGFSVYKMPKFLTET 294
F TNPQ + +NE D V++SL Q + E IGF V+ +P +
Sbjct: 408 FCTNPQFWLRINEMDKTCDQGQNNVLVSLIQKPDKRNRRLAEHHGIGFCVFAVPPEMRSE 467
Query: 295 AN--QMFFKRIKSTINSQYTNSRQVSQRCQLESGAYLIMPTTFEPREEAQFTLRIYSNKP 352
FF R + + ++RQV + +LE G YLI+P+T+ P + A F L I
Sbjct: 468 GKFRSSFFNRKPVVTSGNFQDARQVMKFFRLEPGEYLIVPSTYLPNKNADFILSILCKND 527
Query: 353 LKMKVLDDPPQMTKAALVKAPPGSDSNGFFQYET-------LFLQLADAHRTIDIFELQE 405
++++ D + K LV S+S G + E LF Q +D ++ +D +LQ+
Sbjct: 528 IQIQ--KDTERTEKDFLVDLIGVSES-GCTEKEDEESKTKFLFRQYSDQYKVVDAEKLQQ 584
Query: 406 L----------------LDACLPNDYIKS-CVS-----------IDTLKHLQLVFKTHAR 437
L LD+C + CV+ D + + +F
Sbjct: 585 LLHENLLRGRKNAEGFGLDSCRSMIAMSDFCVTGRLQGSEFVRLWDRITTYRDIFYNMDS 644
Query: 438 EKMGVLRVERLRDALKDVGFIVPERVISLLVFRYMRKDGMLRFGDFVSAVMHLH 491
K GVL + L++AL+ G + E +++L+V RY + F+ VM L+
Sbjct: 645 SKDGVLSLNELQNALEKTGLHLNEDILNLMVVRYGGASEQISLEGFICLVMRLN 698
>UniRef50_P20807 Cluster: Calpain-3; n=55; Euteleostomi|Rep:
Calpain-3 - Homo sapiens (Human)
Length = 821
Score = 111 bits (267), Expect = 4e-23
Identities = 78/246 (31%), Positives = 127/246 (51%), Gaps = 29/246 (11%)
Query: 130 SVINIFQVDTTNEPVYLIRLRRPLGHGETPISHIVLDTALWKTIPQYERDRL---MTASK 186
SV + +V E V L+RLR P G E S W + + E+ RL +T
Sbjct: 337 SVTGLDEVPFKGEKVKLVRLRNPWGQVEWNGSWSDRWKD-WSFVDKDEKARLQHQVTEDG 395
Query: 187 GVWMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQKWQMKMHQGGWKRGVSAGGCRNYV 246
WM + DF F ++E+ +L + +++ + Q W + +++G W RG SAGGCRN+
Sbjct: 396 EFWMSYEDFIYHFTKLEICNLTADALQSD----KLQTWTVSVNEGRWVRGCSAGGCRNFP 451
Query: 247 NFFHTNPQVQIMLNEPD----------TVIISLNQHSIMEPK-------VIGFSVYKMPK 289
+ F TNPQ ++ L E D + +++L Q + + + IGF++Y++PK
Sbjct: 452 DTFWTNPQYRLKLLEEDDDPDDSEVICSFLVALMQKNRRKDRKLGASLFTIGFAIYEVPK 511
Query: 290 FLTETANQM---FFKRIKSTINSQ-YTNSRQVSQRCQLESGAYLIMPTTFEPREEAQFTL 345
+ + FF S S+ Y N R+VSQR +L Y+I+P+T+EP +E +F L
Sbjct: 512 EMHGNKQHLQKDFFLYNASKARSKTYINMREVSQRFRLPPSEYVIVPSTYEPHQEGEFIL 571
Query: 346 RIYSNK 351
R++S K
Sbjct: 572 RVFSEK 577
Score = 40.3 bits (90), Expect = 0.12
Identities = 19/58 (32%), Positives = 33/58 (56%), Gaps = 4/58 (6%)
Query: 11 VGDKWLVSCLGVLYLCKGLFYRVVPADQRMDTSYAGVFRLHGSYEALKYGSLLDGLAD 68
+GD W ++ + L L + L +RV+P DQ +YAG+F ++ +YG +D + D
Sbjct: 126 LGDCWFLAAIACLTLNQHLLFRVIPHDQSFIENYAGIFH----FQFWRYGEWVDVVID 179
Score = 38.7 bits (86), Expect = 0.36
Identities = 18/76 (23%), Positives = 37/76 (48%)
Query: 425 LKHLQLVFKTHAREKMGVLRVERLRDALKDVGFIVPERVISLLVFRYMRKDGMLRFGDFV 484
+K Q +FK + ++ G + +R+A+ D GF + ++ ++ RY K + F F+
Sbjct: 724 IKAWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDIITMRYADKHMNIDFDSFI 783
Query: 485 SAVMHLHRVFVQVYDF 500
+ L +F + F
Sbjct: 784 CCFVRLEGMFRAFHAF 799
Score = 38.3 bits (85), Expect = 0.48
Identities = 15/27 (55%), Positives = 20/27 (74%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITE 75
+LHGSYEALK G+ + + D TGG+ E
Sbjct: 211 KLHGSYEALKGGNTTEAMEDFTGGVAE 237
>UniRef50_Q8MQV0 Cluster: Muscle-specific calpain; n=3;
Pleocyemata|Rep: Muscle-specific calpain - Homarus
americanus (American lobster)
Length = 575
Score = 109 bits (262), Expect = 2e-22
Identities = 94/348 (27%), Positives = 156/348 (44%), Gaps = 47/348 (13%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVM--PELSDGSALRTLLDTSSVVTAHYFPPV 106
+L+G YE+L+ G++ + + DLTGG+ E I + P S L +++ P
Sbjct: 223 KLYGGYESLRGGNINESMVDLTGGVVEMIDLRNPPPKLFSTLWKAYRRGALIGTAIEPDQ 282
Query: 107 TIISV-FFLSLPTGIRLVKIRLRRSVINIFQV-DTTNEPVYLIRLRRPLGHGETPISHIV 164
+ I LS +R R + ++I V LIRL P G+
Sbjct: 283 SNIQAESILSNGLIMRHAYSITRVTTVDIKSVVPRLQGKAQLIRLHNPWGNEAEWKGSWS 342
Query: 165 LDTALWKTIPQYERDRLMTASKG---VWMLFSDFQRLFPRIEMVHL----------DTET 211
+ W +I E+ RL + WM F DF F +E+ + D E
Sbjct: 343 DKSPEWNSITPEEKQRLKLNFEDDGEFWMSFQDFASNFTTVEICDVTPEVFDHDDSDDEN 402
Query: 212 SRAELSLSEKQKWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPD-------- 263
++ S ++WQM M++G W SAGGCRN++N F +NPQ + L +PD
Sbjct: 403 GNTKMEESAPKRWQMVMYEGAWAAHHSAGGCRNFINTFASNPQFTVQLEDPDDDDDDDDD 462
Query: 264 ------------TVIISLNQHSIMEPK-------VIGFSVYKMPKFLT--ETANQMFFKR 302
T+++SL Q ++ + K IGF++Y +P + + + FFK
Sbjct: 463 DDDDDDDDRGQCTIVVSLMQKNVRQLKRYGVDYVPIGFTIYALPANMQPGQKLDTEFFKY 522
Query: 303 IKSTINSQ-YTNSRQVSQRCQLESGAYLIMPTTFEPREEAQFTLRIYS 349
S + N+R+++ R + G Y+I+P+TFEP +F +RI++
Sbjct: 523 NPSLAKVPFFLNTRELTTRFRFPPGLYVIIPSTFEPEMTGEFLIRIFT 570
Score = 35.1 bits (77), Expect = 4.4
Identities = 16/38 (42%), Positives = 23/38 (60%)
Query: 11 VGDKWLVSCLGVLYLCKGLFYRVVPADQRMDTSYAGVF 48
+GD WL++ + L L +F+ VVP DQ YAG+F
Sbjct: 138 LGDCWLLAAVSNLTLNPQMFHAVVPRDQGFIDLYAGIF 175
>UniRef50_UPI0000D9D3A6 Cluster: PREDICTED: similar to Calpain-2
catalytic subunit precursor (Calpain-2 large subunit)
(Calcium-activated neutral proteinase 2) (CANP 2)
(Calpain M-type) (M-calpain) (Millimolar-calpain)
(Calpain large polypeptide L2); n=1; Macaca mulatta|Rep:
PREDICTED: similar to Calpain-2 catalytic subunit
precursor (Calpain-2 large subunit) (Calcium-activated
neutral proteinase 2) (CANP 2) (Calpain M-type)
(M-calpain) (Millimolar-calpain) (Calpain large
polypeptide L2) - Macaca mulatta
Length = 884
Score = 105 bits (252), Expect = 3e-21
Identities = 124/469 (26%), Positives = 207/469 (44%), Gaps = 62/469 (13%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVMPELSDGSALRTLLDTSSVVTAHYFPPVTI 108
+L GSYE L+ G + + L D TGG+T +I + E A L D + T + T+
Sbjct: 336 KLSGSYEDLQSGQVSEALVDFTGGVTMTINLAE-----AHGNLWDILTKATYNR----TL 386
Query: 109 ISVFFLSLPTGIR---LVKIRLRRSVINIFQVDTTNEPVYLIRLRRPLGHGETPISHIVL 165
I S I LV+ +V I +V + P YL++LR P G E
Sbjct: 387 IGCQTHSGKEKILENGLVEGHAY-TVTGIRKVTCKHRPEYLVKLRNPWGQVEWK-GDWSD 444
Query: 166 DTALWKTIPQYERDRLMTASKG--VWMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQK 223
++ W+ + E+ L+ WM DF+ F + + L + LS QK
Sbjct: 445 SSSKWELLSPKEKILLLRKDNDGEFWMTLQDFKTHFVLLVICKL----TPGLLSQEAAQK 500
Query: 224 WQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPD---------TVIISLNQ--- 271
W M +G W++G +AGG R + F NPQ + + P+ +V++SL Q
Sbjct: 501 WTYTMREGRWEKGSTAGG-RRHPGTFWKNPQFLLSVWRPEEGRRSLRPCSVLVSLLQKPR 559
Query: 272 HSIMEPK---VIGFSVYKMPKFLTETAN---QMFFKRIKSTINSQYTNSRQVSQRCQLES 325
H + K IGF +Y++ K+ + + F + + ++ ++VSQ LE
Sbjct: 560 HRCRKRKPHLAIGFYLYRVNKYHDDQRRLPPEFFQRNTPLSQPDRFLKEKEVSQELCLEP 619
Query: 326 GAYLIMPTTFEPREEAQFTLRIYSNKPLKMKVLDDPPQMTKAALVKAPPGSDSNGFFQYE 385
G YLI+P T E ++++F LR++S K + ++ + + + G D FF
Sbjct: 620 GTYLIVPCTSEANQKSEFILRVFSRKHIFYEIGSNSGVVFSKEIEDQNEGQDE--FF--- 674
Query: 386 TLFLQLADAHRTIDIFELQELLDACLPNDYIKSCVSIDTLKHLQLVFKTHAREK-MGVLR 444
T F + +A T+ I E ++L LK Q VF H ++ G L
Sbjct: 675 TKFFEKLNASGTMSIQEFRDLW---------------KQLKLYQKVF--HKQDNGSGYLN 717
Query: 445 VERLRDALKDVGFIVPERVISLLVFRYMRKDGMLRFGDFVSAVMHLHRV 493
E+LR A+K+ G ++ + V L++ RY + F FV ++ + +
Sbjct: 718 WEQLRAAMKEAGIVLSDDVCQLMLVRYGCPRLQMGFVSFVHLMLRVENM 766
Score = 37.9 bits (84), Expect = 0.63
Identities = 17/39 (43%), Positives = 23/39 (58%)
Query: 11 VGDKWLVSCLGVLYLCKGLFYRVVPADQRMDTSYAGVFR 49
VGD W ++ L L L + + RVVP +Q YAG+FR
Sbjct: 250 VGDCWFLAALQALTLHQDILSRVVPLNQSFTEKYAGIFR 288
>UniRef50_UPI0000EBD30A Cluster: PREDICTED: similar to calpain Lp82;
n=8; Amniota|Rep: PREDICTED: similar to calpain Lp82 -
Bos taurus
Length = 906
Score = 103 bits (247), Expect = 1e-20
Identities = 123/487 (25%), Positives = 215/487 (44%), Gaps = 56/487 (11%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVMPELSDGSALRTLLDTSSVVTAHYFPPVTI 108
+L GSYE L+ G + + L D TGG+T +I + E D +L D V+T + I
Sbjct: 184 KLSGSYEDLQRGQVSEALVDFTGGVTMTIKLSEAPD-----SLWD---VLTRAMYSRTLI 235
Query: 109 ISVFFLSLPTGIRLVKIRLRRSVINIFQVDTTNEPVYLIRLRRPLGHGETPISHIVLDTA 168
T LV ++ + +V T + P YL+RLR P G E ++
Sbjct: 236 GCQTHCGARTPYGLVDGHAY-TLTGLRKVTTRHGPEYLVRLRNPWGKIEWK-GDWSDSSS 293
Query: 169 LWKTIPQYERDRLMTASKG--VWMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQKWQM 226
+W + E+ L+ WM DF+ F M+ + + S L+ QKW
Sbjct: 294 MWDLLSPKEKILLLRKDDDGEFWMSLQDFKAHF----MLLVICKLSPGLLTQEVGQKWSY 349
Query: 227 KMHQGGWKRGVSAGG-CRNYVNFFHTNPQVQIMLNEPD---------TVIISLNQ----- 271
M +G W+ G +AGG ++ + F NPQ + + P +V++SL Q
Sbjct: 350 TMLEGRWENGRTAGGQMKSPQDTFWKNPQFLLSVWRPQEGKRSQLLCSVLVSLLQKPRHR 409
Query: 272 HSIMEPKV-IGFSVYKMPKFLT---ETANQMFFKRIKSTINSQYTNSRQVSQRCQLESGA 327
H +P + IGF ++++ + + ++ F+K + + + ++VS+ LE G
Sbjct: 410 HRNWKPHLAIGFYLFRVNQIFDAQKKLPSEFFWKNASLSCRATFLTEKEVSRELWLEPGT 469
Query: 328 YLIMPTTFEPREEAQFTLRIYSNKPLKMKVLDDPPQMTKAALVKAPPGSD---SNGFFQY 384
Y+I+P T E +E++F LR++S K + ++ + + +V G D + F +Y
Sbjct: 470 YVIVPCTSEACQESEFVLRVFSRKHIFYEIGSNSRVIFSKEIVDQSEGKDEFFTKLFEKY 529
Query: 385 -ETLFLQLADAHRTI---DIFELQEL--LDAC-----LPNDYIKSCVSIDTLKHL----- 428
E +QL + + + Q L L+AC L + VSI + L
Sbjct: 530 PEINAIQLQNILNHMPWSGLGSKQPLFSLEACQGILALLDLNASGTVSIQEFRDLWKQLM 589
Query: 429 --QLVFKTHAREKMGVLRVERLRDALKDVGFIVPERVISLLVFRYMRKDGMLRFGDFVSA 486
Q VF + G L +LR A+++ G ++ + V L++ RY D + F FV
Sbjct: 590 FYQEVFHKQDTNRSGSLNWAQLRAAMREAGIMLSDDVCQLMLIRYGGPDLQMNFVRFVRL 649
Query: 487 VMHLHRV 493
++ + +
Sbjct: 650 MLRVENM 656
Score = 36.3 bits (80), Expect = 1.9
Identities = 16/39 (41%), Positives = 23/39 (58%)
Query: 11 VGDKWLVSCLGVLYLCKGLFYRVVPADQRMDTSYAGVFR 49
VGD W ++ L L L + + RVVP +Q YAG+F+
Sbjct: 98 VGDCWFLAALQALSLHQDILSRVVPLNQSFTKKYAGIFQ 136
>UniRef50_Q9N4B2 Cluster: Calpain family protein 6; n=2;
Caenorhabditis elegans|Rep: Calpain family protein 6 -
Caenorhabditis elegans
Length = 790
Score = 103 bits (246), Expect = 1e-20
Identities = 95/335 (28%), Positives = 148/335 (44%), Gaps = 45/335 (13%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVMPELSDGSALRTLLDTSSVVTAHYFPPVTI 108
+L+G+YE L G+ + L D TGG+TE + T D +++ A + +
Sbjct: 294 KLYGTYEHLDGGTTTEALEDFTGGLTEFYDL----------TSTD-KTMILAMIMKGMQM 342
Query: 109 ISVFFLSLPTGIRLVKIRLRR--------SVINIFQVDTTNEPVYLIRLRRPLGHGETPI 160
S+F S+ R + +L SV + V+T E V L+R+R P G E
Sbjct: 343 GSLFACSIDPDPREKEAQLANGLVRGHAYSVTGVHTVETDKEKVALLRIRNPWGDTEWN- 401
Query: 161 SHIVLDTALWKTIPQYERDRLMTASKG---VWMLFSDFQRLFPRIEMVHLDTE-----TS 212
++LW+ + Q +R+++ K WM DF F ++ +L + T
Sbjct: 402 GDWSDKSSLWEQVDQEQREKMEFRIKEDGEFWMCLDDFMAQFANLDCCNLSADVMHEITE 461
Query: 213 RAELSLSEKQ--KWQMKMHQGGW-KRGVSAGGCRNYVNFFHTNPQVQIML-------NEP 262
E+ + EKQ +W K G W R +AGGC N N F TNPQ + N+
Sbjct: 462 MTEIEVMEKQSKQWIQKSADGEWCSRKGTAGGCSNNENTFCTNPQYETYFRATSPSSNDK 521
Query: 263 DTVIISLNQ-------HSIMEPKVIGFSVYKMPKFLTETANQMFFKRIKSTINSQYTNSR 315
TVI ++ Q H ++ IG SVYKM + +M + + R
Sbjct: 522 CTVIAAVFQKYRRNQLHRGLDMLQIGLSVYKMSGPNEKVTAEMMKTHAPIASTKLFVDYR 581
Query: 316 QVSQRCQLESGAYLIMPTTFEPREEAQFTLRIYSN 350
+ R + G Y+I+P TFEP +A+F LR +SN
Sbjct: 582 EAVVRFTVPPGYYVIVPCTFEPNHDAEFLLRTFSN 616
Score = 40.3 bits (90), Expect = 0.12
Identities = 20/59 (33%), Positives = 32/59 (54%), Gaps = 4/59 (6%)
Query: 10 TVGDKWLVSCLGVLYLCKGLFYRVVPADQRMDTSYAGVFRLHGSYEALKYGSLLDGLAD 68
++G+ W ++ L LFYRVVP DQ +YAG+F ++ +YG +D + D
Sbjct: 208 SLGNCWFLAAAATLAQRDELFYRVVPPDQSFTENYAGIFH----FQFWRYGEWVDVVID 262
>UniRef50_Q4SYK3 Cluster: Chromosome 10 SCAF12030, whole genome
shotgun sequence; n=3; Clupeocephala|Rep: Chromosome 10
SCAF12030, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 881
Score = 98.3 bits (234), Expect = 4e-19
Identities = 91/332 (27%), Positives = 149/332 (44%), Gaps = 35/332 (10%)
Query: 40 MDTSYAGVFRLHGSYEALKYGSLLDGLADLTGGITESIVM--PELSDGSALRTLLDTSSV 97
M T R+ GSY + GS + L D TGG+ + + P L+ + + S+
Sbjct: 562 MHTEQLCPLRVCGSYADMNAGSPSEALVDFTGGVHICVQLSDPPLNLWELMYRAGNAGSL 621
Query: 98 VTAHYFPPVTIISVFFLSLPTGIRLVKIRLRRSVINIFQVDTTNEPVYLIRLRRPLGHGE 157
+ + +V LP G LV+ +V + QV + PV L+RL P G GE
Sbjct: 622 MGCGTQGETSTNTV----LPNG--LVQGHAY-TVTGVKQVSSQGRPVNLVRLWNPWGQGE 674
Query: 158 TPISHIVLDTALWKTIPQYERDRLMTASKG--VWMLFSDFQRLFPRIEMVHLDTETSRAE 215
+ LW T+ +R+ + WM DF++ + +++ L + +
Sbjct: 675 WN-GDWSDRSPLWSTVSTEDREMCLRVQDNGEFWMKLEDFRQFYNDLDICCLCPDFLDDD 733
Query: 216 LSLSEKQKWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNE-----------PDT 264
S W+ ++G W G+SAGGC N ++ F NPQ ++ ++E T
Sbjct: 734 ASCH----WKSYCYEGRWVAGISAGGCLNNIDSFWINPQYRVKVDELLSECSSGSSDEKT 789
Query: 265 VIISLNQ------HSIMEPKVIGFSVYKMPKFLTETANQMFFKRIKSTINSQ-YTNSRQV 317
+++SL Q ++ IGFSV++ K T FF+R S+ Y N+R+V
Sbjct: 790 MLVSLMQKPDKRNRRLVHNLHIGFSVFEY-KSHTGKFPDTFFRRNYPVAQSKTYVNAREV 848
Query: 318 SQRCQLESGAYLIMPTTFEPREEAQFTLRIYS 349
+ L G YLI+P+TF+P E A + L + S
Sbjct: 849 MELLALRPGEYLIVPSTFQPNETASYLLTVLS 880
Score = 37.9 bits (84), Expect = 0.63
Identities = 18/72 (25%), Positives = 38/72 (52%), Gaps = 1/72 (1%)
Query: 419 CVSIDTLKHLQLVFKTHAREKMGVLRVERLRDALKDVGFIVPERVISLLVFRYMRKDGML 478
C+ +K+ + + T + G L ++ LR+A +G ++ + ++SL+V RY G +
Sbjct: 489 CLWNKVIKYRDIFYLTDV-SRTGTLSLKELRNAFNTLGKMLSDDMLSLMVLRYGASSGHM 547
Query: 479 RFGDFVSAVMHL 490
F+S ++ L
Sbjct: 548 SLESFISLILRL 559
>UniRef50_Q4SUI7 Cluster: Chromosome 16 SCAF13910, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 16 SCAF13910, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 449
Score = 97.9 bits (233), Expect = 6e-19
Identities = 93/321 (28%), Positives = 142/321 (44%), Gaps = 33/321 (10%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVMPEL-SDGSALRT-LLDTSSVVT-AHYFPP 105
+L G Y AL G + + D+TGG+TE + + L D AL + LL +++ A+ P
Sbjct: 140 KLKGGYRALDMGFSHEAMVDMTGGVTEVLNVAALPGDLPALLSHLLSKGALINCANSQGP 199
Query: 106 VTIISVFFLSLPTGIRLVKIRLRRSVINIFQVDTTNEPVYLIRLRRPLGHGETPISHIVL 165
L G+ +V R S+ + +V T+ L+RL P G+ E L
Sbjct: 200 --------LEQKNGLGIV-FRHAYSLTAVEEVKTSRGTECLVRLLNPWGNTEWEGPWSDL 250
Query: 166 DTALWKTIPQYERDRLMTASKG---VWMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQ 222
W T+ E+ RL S+ WM SDF++ F +E+ HL T+ ++ S Q
Sbjct: 251 KGPEWNTVSFEEQKRLGRVSQDDGEFWMSVSDFRQNFGMMEVCHL-TQAFQS----SSMQ 305
Query: 223 KWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPD---------TVIISLNQHS 273
W MH G W ++AGG N F NPQ L++ D + I++L Q
Sbjct: 306 PWSCSMHHGNWVPSITAGG-PPIGNLFWQNPQFSFTLSDEDGSRRNSKTCSFILALMQKH 364
Query: 274 IMEPKV---IGFSVYKMPKFLTETANQMFFKRIKSTINSQYTNSRQVSQRCQLESGAYLI 330
+ I VY+ T + K + Y N R+V R L G Y+I
Sbjct: 365 QRRSGINLSIALHVYQALPEKTHLSPTDLSKMRPVLFSPHYANHREVVLRSSLPPGRYII 424
Query: 331 MPTTFEPREEAQFTLRIYSNK 351
+P+T EP ++ QF LR+ + K
Sbjct: 425 IPSTSEPNQQGQFLLRVLTEK 445
>UniRef50_A7SN59 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 645
Score = 97.9 bits (233), Expect = 6e-19
Identities = 90/340 (26%), Positives = 148/340 (43%), Gaps = 42/340 (12%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVMPE----------------LSDGSALRTLL 92
+L G+YEAL GS D L D TGG+ E+I + L G ++L+
Sbjct: 171 KLAGTYEALAAGSTADALVDFTGGVAEAISLSNGGYAEDQEKRLQLFKTLERGHKEKSLM 230
Query: 93 DTSSVVTAHYFPPVTIISVFFLSLPTGIRLVK-IRLRRSVINIFQVDTTNEPVYLIRLRR 151
S + + + G+ +VK + + ++++F + Y+IRLR
Sbjct: 231 SASIKINNRNEMEQRLDTGLIKGHAYGVTMVKKVTVGEGLLSLFN----KKHFYMIRLRN 286
Query: 152 PLGHGETPISHIVLDTALWKTIPQYERDRLMTASKG---VWMLFSDFQRLFPRIEMVHLD 208
P G E ++ WK + +R ++ + WM F DF R F + H+
Sbjct: 287 PWGEKEWN-GRWSDESEEWKKLKPGDRKKMGIVFENDGEFWMEFDDFCREFTDCTLCHV- 344
Query: 209 TETSRAELSLSEKQKWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIML--NEPDTVI 266
++A + KQ W + H W +G +AGGC + F NPQ + NE + +
Sbjct: 345 --INKAMIHKVFKQ-WHIYKHNYNWTQGQNAGGCVQNQDTFLKNPQYAFSITDNEGEDAM 401
Query: 267 ISLNQHSIMEPK-------VIGFSVYKMPKFLTETANQMFFKRIKSTINSQYTNSRQVSQ 319
+SL Q + K IGF + K+ + + MF K +S + N+R+V
Sbjct: 402 VSLMQEDRRKDKSKGVGNLTIGFYIMKVEENRKYRVHSMFPK----AGDSIFINAREVMN 457
Query: 320 RCQLESGAYLIMPTTFEPREEAQFTLRIYSNKPLKMKVLD 359
R L +G YL++P+T+EP F +RI++ K LD
Sbjct: 458 RFFLAAGRYLVVPSTYEPHTPGHFMMRIFTRKRSNAMFLD 497
>UniRef50_UPI0000D56B6A Cluster: PREDICTED: similar to calpain 11;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
calpain 11 - Tribolium castaneum
Length = 693
Score = 95.5 bits (227), Expect = 3e-18
Identities = 80/319 (25%), Positives = 145/319 (45%), Gaps = 19/319 (5%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVMPELSDGSALRTLLDTSSVVTAHYFPPVTI 108
+ +G YE L GS L DLTGGI +S + D +L+++ ++ VT
Sbjct: 182 KFYGCYENLAQGSTTRALQDLTGGIVQSFGLTH-QDRFLTFQVLNSAVPRSSLLIATVTQ 240
Query: 109 ISVFFLSLPTGIRLVKIRLRRSVINIFQVDTTNEPVYLIRLRRPLGHGETPISHIVLDTA 168
L L+ + SV + +V L+RLR P GE +
Sbjct: 241 EKENKRQLRLRNGLIT-QHAYSVTGLARVRGPQGETPLVRLRNPWARGEWTGAWSERSWE 299
Query: 169 LWKTIPQYERDRLMT--ASKG-VWMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQKWQ 225
W + +++ L A+ G WM F DF + F ++++VH+ + E +L KQ W+
Sbjct: 300 -WDGLSTRDKELLSVRVANDGEFWMSFEDFSKHFTQLDLVHIGPDDWMMESALHSKQPWR 358
Query: 226 MKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPDT----VIISLNQH---SIMEPK 278
+ + W+ G +AGG +YV+ NPQ + + + V++S+ Q S+ + K
Sbjct: 359 AVLARRRWRAGYNAGGGPSYVDTTSMNPQFHVQIPRTSSNKCHVVVSITQSYETSVADSK 418
Query: 279 ------VIGFSVYKMPKFLTETANQMFFKRIKSTINSQYTNSRQVSQRCQLESGAYLIMP 332
IGF+VY++P + ++K + ++ +R+V L G Y+++P
Sbjct: 419 KKKPLYAIGFAVYEVPHSMQRLTPHFVADKLKPLDVTNHSIAREVVTFFTLPPGDYIVVP 478
Query: 333 TTFEPREEAQFTLRIYSNK 351
T P + +F LR+++++
Sbjct: 479 QTNIPNLDGKFLLRVFTDE 497
Score = 36.7 bits (81), Expect = 1.5
Identities = 18/41 (43%), Positives = 24/41 (58%), Gaps = 2/41 (4%)
Query: 11 VGDKWLVSCLGVLYLCKGLFYRVVPADQRMDTS--YAGVFR 49
+GD+WL++ + L L R+VP DQ D S Y GVFR
Sbjct: 95 LGDQWLLAAVASLALTPRFLDRIVPPDQGFDNSHNYCGVFR 135
>UniRef50_Q4T7F6 Cluster: Chromosome undetermined SCAF8104, whole
genome shotgun sequence; n=2; Tetraodontidae|Rep:
Chromosome undetermined SCAF8104, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 788
Score = 94.3 bits (224), Expect = 7e-18
Identities = 102/358 (28%), Positives = 163/358 (45%), Gaps = 64/358 (17%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVMPE---LSDGSALRTLLDTSSVVTAHYFPP 105
+++G YEAL G+ D L D TGG++E + + E SD +A L + V+ H
Sbjct: 317 KVYGCYEALDGGNTADALVDFTGGVSEPVDLLEGQMASDEAARNQLFER--VLKVHNRDG 374
Query: 106 V-------TIISVFFLSLPTGI---------RLVKIRLRRSVINIFQVDTTNEPVYLIRL 149
+ T + L G+ + K+RL ++ F+ +E +++IR+
Sbjct: 375 LISCSIRATTVEDMEARLDCGLVKGHAYAVTDVRKVRLGHGLLAFFK----SEKLHMIRM 430
Query: 150 RRPLGHGET--PISHIVLDTALWKTIPQYERDRLMTASKG---VWMLFSDFQRLFPRIEM 204
R P G E P S + W + + ER++L + WM F DF + F + +
Sbjct: 431 RNPWGEKEWSGPWSD---SSEEWNKVSKSEREKLGVTVQDDGEFWMTFDDFCQYFTDLIL 487
Query: 205 VHLDTETSRAELSLSEKQKWQMKMHQGGWKRGVS-----AGGCRNYVNFFHTNPQVQIML 259
L TS LS + W+ ++ +G W +GGC N+ N F NPQ +
Sbjct: 488 CRL-INTSY----LSIHKTWEEEVMRGSWTLRQDPLRNRSGGCINHKNTFLQNPQYVFDV 542
Query: 260 NE-PDTVIISLNQH----SIMEPK----VIGFSVYKMP---KFLTETANQMFFKRIKSTI 307
+ D V+I L Q + E K IGF ++++ K+ + Q
Sbjct: 543 KKVEDEVLICLQQKEKRATAREGKGENLAIGFDIHRVELNRKYRVHSPQQ-------KVA 595
Query: 308 NSQYTNSRQVSQRCQLESGAYLIMPTTFEPREEAQFTLRIYSNKPLKMK--VLDDPPQ 363
S Y NSR V R +L+ G Y+I+PTTFEP ++ F LR++++ P K LD+PPQ
Sbjct: 596 GSIYINSRCVFLRKELKEGRYVIIPTTFEPGQQGDFLLRVFTDVPSDCKELTLDEPPQ 653
>UniRef50_Q4SQP6 Cluster: Chromosome undetermined SCAF14531, whole
genome shotgun sequence; n=3; Tetraodontidae|Rep:
Chromosome undetermined SCAF14531, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 722
Score = 93.1 bits (221), Expect = 2e-17
Identities = 71/222 (31%), Positives = 106/222 (47%), Gaps = 19/222 (8%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVMPELSDG--SALRTLLDTSSVVTAHYFPPV 106
+L+G YEAL GS +G D TGG+TE + + S + L+ S++ +
Sbjct: 194 KLNGCYEALSGGSTSEGFEDFTGGVTEMYELQKAPSDLYSIICRALERGSLLGCS----I 249
Query: 107 TIISVFFLSLPTGIRLVKIRLRRSVINIFQVDTTNEPVYLIRLRRPLGHGET--PISHIV 164
I S F + T +LVK SV +V P L+R+R P G E P S
Sbjct: 250 NITSKFDMEAVTFKKLVKGHAY-SVTAADEVAYRGTPTKLVRIRNPWGEVEWTGPWSD-- 306
Query: 165 LDTALWKTIPQYERDRLMTASKG--VWMLFSDFQ-RLFPRIEMVHLDTETSRAELSLSEK 221
++ W ++ + R RL S+ WM R F +E+ +L + L ++
Sbjct: 307 -NSREWDSVDRSVRGRLQNCSEDGEFWMSLQRLPLREFTTLEICNLTPDA----LQNAQL 361
Query: 222 QKWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPD 263
+KW ++QG W+RG +AGGCRNY F NPQ ++ML PD
Sbjct: 362 KKWSTSLYQGEWRRGSTAGGCRNYPATFWLNPQFKLMLKNPD 403
Score = 41.9 bits (94), Expect = 0.039
Identities = 18/72 (25%), Positives = 37/72 (51%)
Query: 423 DTLKHLQLVFKTHAREKMGVLRVERLRDALKDVGFIVPERVISLLVFRYMRKDGMLRFGD 482
+ +K +F+T +K G + +R AL+ GF + + L++ RY D + F +
Sbjct: 631 EKIKRYLTIFRTFDMDKSGTMSSYEMRMALESAGFKLTNNLFQLIILRYTEADMSVDFDN 690
Query: 483 FVSAVMHLHRVF 494
FV+ ++ L ++
Sbjct: 691 FVTCLVRLETMY 702
Score = 35.5 bits (78), Expect = 3.4
Identities = 19/58 (32%), Positives = 30/58 (51%), Gaps = 4/58 (6%)
Query: 11 VGDKWLVSCLGVLYLCKGLFYRVVPADQRMDTSYAGVFRLHGSYEALKYGSLLDGLAD 68
+GD WL++ + L L L +RVVP Q Y G+F ++ ++G LD + D
Sbjct: 109 LGDCWLLAAIASLTLNDNLLHRVVPHGQSFAHGYIGIFH----FQFWQFGEWLDVVID 162
>UniRef50_Q8IAA9 Cluster: Calpain family protein 4, isoform a; n=3;
Caenorhabditis|Rep: Calpain family protein 4, isoform a
- Caenorhabditis elegans
Length = 716
Score = 93.1 bits (221), Expect = 2e-17
Identities = 89/344 (25%), Positives = 151/344 (43%), Gaps = 38/344 (11%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVMPELSDGSALRTLLDTSSVVTAHYFPPVTI 108
+LHG YE L G+ + L D TGG+TE + + + L L+ + +
Sbjct: 377 KLHGGYENLDGGTTAEALEDFTGGLTEYFDLRKSEKAAVLAALVKGMEMGSLFGCSIDAD 436
Query: 109 ISVFFLSLPTGIRLVKIRLRRSVINIFQVDTTNEPVYLIRLRRPLGHGETPISHIVLDTA 168
++ L G+ S+ I + E L+RLR P G+ + ++
Sbjct: 437 ANIKEAQLRNGLVCGHAY---SITAIHSITYYGEDTTLLRLRNPWGNEKEWNGAWSDGSS 493
Query: 169 LWKTIPQYERDRL--MTASKG-VWMLFSDFQRLFPRIEMVHLDTE----------TSRAE 215
W I + + ++ A G WM F DF F ++E+ +L E +RA
Sbjct: 494 EWSKIDEATKKQIDVQFARDGEFWMSFEDFFSNFTQMEVCNLTAEIFDEIAEMTGVNRAT 553
Query: 216 LSLSEKQKWQMKMHQGGW--KRGVSAGGCRNYVNFFHTNPQVQIMLNEPD---------T 264
++ E+ +W M G W K+G +AGGC N + + NPQ P T
Sbjct: 554 ETVEEEHQWHEIMEDGEWSSKKG-TAGGCNNNPSTYPKNPQFSTFFTAPQSSIEADGNVT 612
Query: 265 VIISLNQHSIMEPKV-------IGFSVYKMPKFLTETA--NQMFFKRIKSTINSQ-YTNS 314
VI+++ Q E + IG S+Y + T + FF + + + + N+
Sbjct: 613 VIVAVLQKYRRELRSKGKDVLPIGVSIYSLGAEGTARSPLTAQFFSQNRPIARTTVFVNT 672
Query: 315 RQVSQRCQLESGAYLIMPTTFEPREEAQFTLRIYSNKPLKMKVL 358
R+V+ R ++ G Y+I+P TF+ ++A+F LR+Y+N LK +L
Sbjct: 673 REVTVRFRVPPGQYVIVPCTFDAYDDAEFLLRVYANGTLKSSLL 716
Score = 42.3 bits (95), Expect = 0.029
Identities = 20/58 (34%), Positives = 32/58 (55%), Gaps = 4/58 (6%)
Query: 11 VGDKWLVSCLGVLYLCKGLFYRVVPADQRMDTSYAGVFRLHGSYEALKYGSLLDGLAD 68
+GD W ++ L + L LFYR+VP +Q +YAG+F ++ YG +D + D
Sbjct: 292 LGDCWFLAALANITLYDALFYRIVPPNQSFTENYAGIFH----FQFWHYGKWVDVVVD 345
>UniRef50_UPI000065EB25 Cluster: Homolog of Homo sapiens "Calpain 2,
large [catalytic] subunit precursor; n=2; Takifugu
rubripes|Rep: Homolog of Homo sapiens "Calpain 2, large
[catalytic] subunit precursor - Takifugu rubripes
Length = 750
Score = 90.6 bits (215), Expect = 8e-17
Identities = 61/181 (33%), Positives = 88/181 (48%), Gaps = 22/181 (12%)
Query: 189 WMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQKWQMKMHQGGWKRGVSAGGCRNYVNF 248
WM FSDF R + RIE+ L +T L S K W + G W++G +AGGCRN+
Sbjct: 336 WMSFSDFLRHYSRIEVCTLTPDTI---LDDSVKH-WSVSKFDGTWRKGSTAGGCRNHPYT 391
Query: 249 FHTNPQVQIMLNEPD-------------TVIISLNQHSIMEP----KVIGFSVYKMPKFL 291
F NPQ I L E D +I N+ + + IGF++Y+
Sbjct: 392 FWMNPQFVINLQEEDDDPDDGEEGCSFVVGLIQKNRRKLRKQGEDMHTIGFAIYEFKGQR 451
Query: 292 TETANQMFFKRIKSTINSQ-YTNSRQVSQRCQLESGAYLIMPTTFEPREEAQFTLRIYSN 350
++ FF T S+ + N R+V R +L G YLI+P+TFEP + F +R++S
Sbjct: 452 EVHLDKNFFLSHAQTARSETFINLREVCSRFKLPPGEYLIVPSTFEPHQNGDFCIRVFSE 511
Query: 351 K 351
K
Sbjct: 512 K 512
Score = 40.3 bits (90), Expect = 0.12
Identities = 19/64 (29%), Positives = 32/64 (50%)
Query: 431 VFKTHAREKMGVLRVERLRDALKDVGFIVPERVISLLVFRYMRKDGMLRFGDFVSAVMHL 490
++K + + G + +R A KD GF + + LLV RY + + F +FV +M L
Sbjct: 670 IYKKNDIDNSGTMSTPEMRVAFKDAGFTLNNTIYQLLVARYSDPNMTIDFDNFVGCLMRL 729
Query: 491 HRVF 494
+F
Sbjct: 730 EMMF 733
Score = 37.5 bits (83), Expect = 0.83
Identities = 19/58 (32%), Positives = 33/58 (56%), Gaps = 4/58 (6%)
Query: 11 VGDKWLVSCLGVLYLCKGLFYRVVPADQRMDTSYAGVFRLHGSYEALKYGSLLDGLAD 68
+GD WL++ + L L + + RVVP+DQ YAG+F ++ ++G +D + D
Sbjct: 73 LGDCWLLAAIASLTLNEYVMARVVPSDQGFGDDYAGIFH----FQFWQFGEWVDVVID 126
>UniRef50_UPI00005A06A9 Cluster: PREDICTED: similar to Calpain-9
(Digestive tract-specific calpain) (nCL-4) (CG36
protein); n=1; Canis lupus familiaris|Rep: PREDICTED:
similar to Calpain-9 (Digestive tract-specific calpain)
(nCL-4) (CG36 protein) - Canis familiaris
Length = 520
Score = 90.2 bits (214), Expect = 1e-16
Identities = 66/213 (30%), Positives = 102/213 (47%), Gaps = 15/213 (7%)
Query: 280 IGFSVYKMPKFLTETANQMFFKRIKSTINSQ-YTNSRQVSQRCQLESGAYLIMPTTFEPR 338
IG+++Y+ P E N+ FF+ S S+ + N R+VS R +L G Y+++P+TFEP
Sbjct: 246 IGYAIYQSPS-KDEHLNKDFFRYHASQARSKTFINLREVSDRFKLPPGEYILIPSTFEPH 304
Query: 339 EEAQFTLRIYSNKPLKMKVLDDPPQMTKAALVK-APPGSDSNGFFQYETLFLQLADAHRT 397
+EA F LRI+S K + +D + L K P G ++ Q+ LF Q+A
Sbjct: 305 QEADFCLRIFSEKKAITRDMDGDVDIDLPELPKPTPAGQETEEELQFRALFDQIAGETSG 364
Query: 398 IDIFELQELLDACLPNDYIKSCVSIDTLKHLQLVFKTHAREKMGVLRVERLRDALKDVGF 457
E +E V D LK +F +K G + LR ALK GF
Sbjct: 365 NGKLEFKEFK------------VFWDKLKKWTNLFHQFDTDKSGTMSSYELRTALKATGF 412
Query: 458 IVPERVISLLVFRYMRKDGMLRFGDFVSAVMHL 490
+ ++ L+V RY + L F DF++ ++ L
Sbjct: 413 QLGCHLLQLIVLRYADEGLQLTFDDFLNCLVRL 445
Score = 59.7 bits (138), Expect = 2e-07
Identities = 52/194 (26%), Positives = 87/194 (44%), Gaps = 22/194 (11%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVMPELSDG--SALRTLLDTSSVVTAHYFPPV 106
+L+GSYEALK GS ++ + D TGG+ E+ E + L L S+V
Sbjct: 52 KLNGSYEALKGGSTIEAMEDFTGGVAETFATKEAPENFYEILEKALKRGSLVGCS----- 106
Query: 107 TIISVFFLSLPTGIRLVKIRLRRSVINIFQVDTTNEPVYLIRLRRPLGHGETPISHIVLD 166
I V F + L+++R + + V + L +G T +SH+ D
Sbjct: 107 --IDVNFRGQK--MELIRVRNPWGQVEWNGSWSDRREVLKVLLALQARYGLT-VSHLEGD 161
Query: 167 T---ALWKTIPQYERDRLMTASKG---VWMLFSDFQRLFPRIEMVHLDTETSRAELSLSE 220
+ + W+++ E+ RL + WM F DF+ F ++E+ +L + L
Sbjct: 162 SFRSSEWRSVGPAEQKRLCHTALDDGEFWMAFRDFKAHFDKVEICNLTPDA----LEEDA 217
Query: 221 KQKWQMKMHQGGWK 234
KW++ +HQG WK
Sbjct: 218 LHKWEVTVHQGSWK 231
>UniRef50_Q5IW11 Cluster: Calpain T; n=1; Gecarcinus lateralis|Rep:
Calpain T - Gecarcinus lateralis (Blackback land crab)
Length = 639
Score = 90.2 bits (214), Expect = 1e-16
Identities = 96/344 (27%), Positives = 145/344 (42%), Gaps = 35/344 (10%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVMP---ELSDGSALRTLLDT-SSVVTAHYFP 104
+L+GSYEAL+ G+L D L DLT G++ + + + D + L S + H
Sbjct: 167 KLYGSYEALEGGNLSDALVDLTSGVSAHLDLTIGGYVDDFEKRKQLFKMMSKEMNEHSLM 226
Query: 105 --PVTIISVFFLSLPTGIRLVK-----IRLRRSV----INIFQVDTTNEPVYLIRLRRPL 153
+T S + T + LVK I R + +F + + V ++RL+ P
Sbjct: 227 CCAITPHSHEEAEMRTNVGLVKGHAYGITACRKINIGDTGLFSIFKGAQKVRMVRLKNPW 286
Query: 154 GHGETPISHIVLDTALWKTIPQYERDRLMTASKG---VWMLFSDFQRLFPRIEMVHLDTE 210
G E + W + ER +L + WM F DF F + + L
Sbjct: 287 GEKEWN-GAFSDGSPEWSQVSASERQKLGLTFEDDGEFWMTFEDFLEHFTDLSICFLINT 345
Query: 211 TSRAELSLSEKQKWQMKMHQGGWKRGVS------AGGCRNYVNFFHTNPQVQIMLNEP-D 263
LS + W + GW GV AGGC N+ + F NPQ + + E D
Sbjct: 346 KF-----LSFSKTWHETVFFNGWTIGVRGHNSDRAGGCPNHKDTFLRNPQFRFDIKEETD 400
Query: 264 TVIISLNQHSIMEPKVIGFS--VYKMPKFLTETANQMFFKRIKSTI-NSQYTNSRQVSQR 320
V+ L Q E K G V E + RI + S Y +R + R
Sbjct: 401 DVVFQLMQKDARERKQEGMQNLVIGFHIMRVEENRKYRVHRIHDAVATSDYIRTRGIFLR 460
Query: 321 CQLESGAYLIMPTTFEPREEAQFTLRIYSNK-PLKMKVLDDPPQ 363
QL+ G Y+I+PTTF+P E +F LRI+++K P + + D P+
Sbjct: 461 EQLKQGRYVIIPTTFKPDETGEFLLRIFTSKDPDAKEPIRDQPK 504
>UniRef50_UPI0000E7FFED Cluster: PREDICTED: similar to calpain 3;
calcium activated neutral protease; CAPN3; CL1; n=1;
Gallus gallus|Rep: PREDICTED: similar to calpain 3;
calcium activated neutral protease; CAPN3; CL1 - Gallus
gallus
Length = 715
Score = 89.0 bits (211), Expect = 3e-16
Identities = 123/517 (23%), Positives = 218/517 (42%), Gaps = 65/517 (12%)
Query: 11 VGDKWLVSCLGVLYLCKGLFYRVVPADQRMDTSYAGVFRLHGSYEALKYGSLLDGLADLT 70
V D+ V+ G L + Y+ V ++ +YA +L+GSYE L+ G + + L D T
Sbjct: 144 VDDRLPVNEAGELVFVSSV-YKNVFWGALLEKAYA---KLYGSYEDLQIGQVSEALVDFT 199
Query: 71 GGITESIVMPELSDGSALRTLLDTSSVVTAHYFPPVTIISVFFLSLPTGIRLVKIRLRRS 130
GG+ I +P D ++T + S+ G+RL+ +L+
Sbjct: 200 GGVNIRIKLPAAPP--------DLWDILTRATYSR----SLMCCQTQLGVRLMVSQLQVF 247
Query: 131 VINIFQVDTTNEPVYLIRLRRPLGHGETPISHIVLDTALWKTIPQYERDRLMTASK---- 186
+ F + + L +G H T + K QY + L+
Sbjct: 248 PVK-FSSAELGTVIPRKKADTRLANGLVA-GHAYTVTGIRKVTCQYGPENLVRLRNPWGK 305
Query: 187 ----GVW---MLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQKWQMKMHQGGWKRGVSA 239
G W M DF+ F + + L + +S + +KW + G W +G +A
Sbjct: 306 IEWNGDWSDRMSLQDFKIHFVDVVICKLTPDL----VSQEDGKKWMYSLKNGRWVKGSTA 361
Query: 240 GGCRNYVN-FFHTNPQ--VQIMLNEPD-------TVIISLNQ-----HSIMEPKV-IGFS 283
GG + F NPQ + I+ +E +V+ISL Q H P + IGFS
Sbjct: 362 GGSLGFSKGMFWMNPQYWLNILASEDSRRNLGSCSVVISLMQKHSSKHRNRAPHLFIGFS 421
Query: 284 VYKMPKFLTETANQM---FFKRIKSTINSQ-YTNSRQVSQRCQLESGAYLIMPTTFEPRE 339
+YK+ + E ++ FF R + Q + + R+V+ LE G Y+I+P+T EP +
Sbjct: 422 LYKVARQQEEINQKLPPAFFTRHQPVNKRQVFLDEREVTCDFHLEPGVYVIVPSTLEPHQ 481
Query: 340 EAQFTLRIYSNKPLKMKVLDDPPQMTKAALVKAPPGSDSNGFFQYETLFLQLADAHRTID 399
E++F LR++S K + ++ + + +V G +E F + + + I+
Sbjct: 482 ESEFILRVFSRKHVLREMGGNSSFILSKEIVDRYEGK------IWEDFFTKHFEKNPEIN 535
Query: 400 IFELQELLDACLPNDY--IKSCVSIDT----LKHLQLVFKTHAREKMGVLRVERLRDALK 453
+LQ +L+ + + S+D L L VF+ + G L + LR A++
Sbjct: 536 AVQLQRILNNVSWRHFQSFRLSFSLDACQSILALLDEVFQKRDTSRSGKLDLVELRAAVQ 595
Query: 454 DVGFIVPERVISLLVFRYMRKDGMLRFGDFVSAVMHL 490
+ G + V +L+ RY D + F F+ ++ +
Sbjct: 596 ETGISLSNEVCNLMAIRYGDPDLKISFESFMCFMLRV 632
>UniRef50_UPI0000E45FAF Cluster: PREDICTED: similar to MGC81349
protein isoform 1; n=3; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to MGC81349 protein
isoform 1 - Strongylocentrotus purpuratus
Length = 642
Score = 88.6 bits (210), Expect = 3e-16
Identities = 94/343 (27%), Positives = 150/343 (43%), Gaps = 40/343 (11%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVM--PEL-SDGSALRTLLDTSSVVTAHYFP- 104
++ G YE L G+ D L D TGG+ E I + PE +D + + L + F
Sbjct: 172 KISGCYENLDGGNTADALVDFTGGVAEQINLADPEFQADQNKKKELHSQMKKYSERRFQM 231
Query: 105 --PVTIISVFFLSLPTGIRLVK-----IRLRRSVINIFQVDTTNEPVYLIRLRRPLGHGE 157
+ + + + T + LVK + +SV E YL+RLR P G E
Sbjct: 232 SASIKVTNAEEMEARTDVGLVKGHAYGVTAVKSVKLGSSGFFKKEKEYLVRLRNPWGEKE 291
Query: 158 T--PISHIVLDTALWKTIPQYERDRLMTASKG---VWMLFSDFQRLFPRIEMVHLDTETS 212
P S + W+ I + +R + ++ WM F F + F + + + +T
Sbjct: 292 WNGPWSD---GSPEWQNISESQRKSIGIVNEDDGEFWMPFDQFCQHFTTLVICRMPNKTY 348
Query: 213 RAELSLSEKQKWQMKMHQGGWKRGVS-----AGGCRNYVNFFHTNPQVQIMLN-EPDTVI 266
LS ++ W + WK + AGGC N F NPQ I ++ + D +I
Sbjct: 349 -----LSLQRTWHESLFISEWKYNSNSVLNRAGGCINVKETFLQNPQFLICVDADKDDII 403
Query: 267 ISLNQHSIM-----EPKVIGFSVYKMPKFLTETANQMFFKRIKSTINSQYTNSRQVSQRC 321
ISL+Q +PK IGF V ++ A+ + K T S Y NSR V +
Sbjct: 404 ISLSQPDTRADQSEDPKTIGFYVMEVESNRKHRAHTIKPK----TFMSAYINSRSVFAKS 459
Query: 322 QLESGAYLIMPTTFEPREEAQFTLRIYSNKPLKMKVL-DDPPQ 363
L G Y+++PT FE + E+ +R++S+ ++K L D P+
Sbjct: 460 TLLRGRYIVVPTIFEAKVESPLMIRVFSDSGAEVKELKKDHPE 502
>UniRef50_O15484 Cluster: Calpain-5; n=32; Deuterostomia|Rep:
Calpain-5 - Homo sapiens (Human)
Length = 640
Score = 88.2 bits (209), Expect = 5e-16
Identities = 97/362 (26%), Positives = 153/362 (42%), Gaps = 52/362 (14%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVMPE---LSDGSALRTLLDTSSVVTAH---Y 102
+L G Y+AL G+ D L D TGG++E I + E +D + L + V +
Sbjct: 169 KLAGCYQALDGGNTADALVDFTGGVSEPIDLTEGDFANDETKRNQLFERMLKVHSRGGLI 228
Query: 103 FPPVTIISVFFLSLPTGIRLVK-----------IRLRRSVINIFQVDTTNEPVYLIRLRR 151
+ ++ + LVK +RL ++ F+ +E + +IRLR
Sbjct: 229 SASIKAVTAADMEARLACGLVKGHAYAVTDVRKVRLGHGLLAFFK----SEKLDMIRLRN 284
Query: 152 PLGHGETPISHIVLDTAL-WKTIPQYERDRLMTASKG---VWMLFSDFQRLFPRIEMVHL 207
P G E + DT+ W+ + + ER+++ + WM F D R F I +
Sbjct: 285 PWGEREW--NGPWSDTSEEWQKVSKSEREKMGVTVQDDGEFWMTFEDVCRYFTDIIKCRV 342
Query: 208 DTETSRAELSLSEKQKWQMKMHQGGWK-----RGVSAGGCRNYVNFFHTNPQVQIMLNEP 262
TS LS + W+ G W R GGC N+ + F NPQ + +P
Sbjct: 343 -INTSH----LSIHKTWEEARLHGAWTLHEDPRQNRGGGCINHKDTFFQNPQYIFEVKKP 397
Query: 263 -DTVIISLNQHSIMEPK--------VIGFSVYKMPKFLTETANQMFFKRIKSTINSQYTN 313
D V+I + Q + IGF +YK+ + + + K S Y N
Sbjct: 398 EDEVLICIQQRPKRSTRREGKGENLAIGFDIYKVEENRQYRMHSLQHKAASSI----YIN 453
Query: 314 SRQVSQRCQLESGAYLIMPTTFEPREEAQFTLRIYSNKPLKMKV--LDDPPQMTKAALVK 371
SR V R G Y+I+PTTFEP +F LR++++ P + LD+PP ++L
Sbjct: 454 SRSVFLRTDQPEGRYVIIPTTFEPGHTGEFLLRVFTDVPSNCRELRLDEPPHTCWSSLCG 513
Query: 372 AP 373
P
Sbjct: 514 YP 515
>UniRef50_UPI00004D856D Cluster: Calpain-6 (Calpamodulin) (CalpM)
(Calpain-like protease X-linked).; n=1; Xenopus
tropicalis|Rep: Calpain-6 (Calpamodulin) (CalpM)
(Calpain-like protease X-linked). - Xenopus tropicalis
Length = 630
Score = 83.0 bits (196), Expect = 2e-14
Identities = 92/331 (27%), Positives = 151/331 (45%), Gaps = 38/331 (11%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVM------PELSDGSALRTLLDT---SSVVT 99
+L+GSYEAL GS + L D +GGI+E I + E + LL +S+++
Sbjct: 170 KLNGSYEALDGGSTAEALIDFSGGISEPIDLLGENFTSEEERKKLFKALLKAHSRASLIS 229
Query: 100 AHYFPPV--TIISVFFLSLPTG----IRLVK-IRLRRSVINIFQVDTTNEPVYLIRLRRP 152
A P ++ V L G + V+ I LR ++++F+ + L+RL+ P
Sbjct: 230 AAIRPTSGQSLEQVLASGLVIGHAYSVTSVRSITLRSGLLSLFRT----HKLRLVRLQNP 285
Query: 153 LGHGETPISHIVLDTALWKTIPQYERDRL-MTASKG--VWMLFSDFQRLFPRIEMVHLDT 209
G GE + + WK I + ER+++ +T S WM + DF F + +
Sbjct: 286 WGSGEWNGAWSD-GSEEWKRISRAEREKMGVTVSDDGDFWMSWGDFCTHFTDLTLCRR-V 343
Query: 210 ETSRAELSLSEKQKWQMKMHQGGWKRGVS-----AGGCRNYVNFFHTNPQVQIMLN-EPD 263
TS +LS + W + W+ +GGC NY + NPQ + + D
Sbjct: 344 NTS----TLSTHKTWTEESALSVWRPDADPLKDRSGGCPNYRETYLHNPQFSFDVTLDQD 399
Query: 264 TVIISLNQHSIMEPKVIGFSVYKMPKFLTET-ANQMF-FKRIKSTINSQ-YTNSRQVSQR 320
+IS+ Q + G + F+ + N+ F R + ++S Y NSR V R
Sbjct: 400 VALISVEQEDRRTQRSEGGENLPIGFFVFKVEVNRKFRLHRTATKVSSSTYINSRSVFLR 459
Query: 321 CQLESGAYLIMPTTFEPREEAQFTLRIYSNK 351
+L+ G Y+I+PTTF P F LR+Y+++
Sbjct: 460 TELQRGRYVILPTTFSPGLIGSFLLRLYTDR 490
>UniRef50_Q61A54 Cluster: Putative uncharacterized protein CBG13923;
n=1; Caenorhabditis briggsae|Rep: Putative
uncharacterized protein CBG13923 - Caenorhabditis
briggsae
Length = 774
Score = 81.8 bits (193), Expect = 4e-14
Identities = 92/339 (27%), Positives = 148/339 (43%), Gaps = 41/339 (12%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVMPELSDGSALRTLLDTSSVVTAHYFPPVTI 108
+L+G YE L G+ + L D TGG+TE + E D S + +L + + + +
Sbjct: 446 KLYGGYEHLDGGTTAEALEDFTGGLTEFFDL-EKGDKSTILAMLVRGMQMGSLFGCSIDA 504
Query: 109 I-SVFFLSLPTGIRLVKIRLRRSVINIFQVDTTNEPVYLIRLRRPLGHGETPISHIVLDT 167
+V L G LV+ S+ I V+T + L+R+R P G+ +
Sbjct: 505 DENVKEAQLTNG--LVRGHAY-SITAIQTVNTYSGQTPLLRIRNPWGNSKEWNGAWSDGA 561
Query: 168 ALWKTIPQYERDRLMT--ASKG-VWMLFSDFQRLFPRIEMVHLD-------TETSRAELS 217
+ W I +R+++ A G WM F DF F ++E +L +E + E+
Sbjct: 562 SEWNQIDPSQREQMNVQFAKDGEFWMSFDDFMSNFTQMECCNLSADVMDEISEMTGVEIH 621
Query: 218 LSEKQKWQMKMHQGGWK-RGVSAGGCRNYVNFFHTNPQVQIMLNEPD---------TVII 267
++ +W K G W R +AGGC+N + NPQ P TVI
Sbjct: 622 DKQRHQWVEKQEDGEWNSRQGTAGGCQNNDTYIQ-NPQYATAFQVPQDAVEHDGKCTVIA 680
Query: 268 SLNQHSIMEPKV-------IGFSVYKMPKF---LTETANQMFFKRIKSTINSQYTNSRQV 317
++ Q E + IGFS+Y+ L A Q R K IN R+V
Sbjct: 681 AVLQKYRREMRSKNLDNLPIGFSIYRSEGGGGPLQSIAGQKPVARTKVFINM-----REV 735
Query: 318 SQRCQLESGAYLIMPTTFEPREEAQFTLRIYSNKPLKMK 356
+ R ++ G Y+I+P TF+ ++A F LR+++N + K
Sbjct: 736 TVRFRVPPGQYVIVPCTFDAYDDASFLLRVFANAEFQTK 774
Score = 45.6 bits (103), Expect = 0.003
Identities = 23/58 (39%), Positives = 34/58 (58%), Gaps = 4/58 (6%)
Query: 11 VGDKWLVSCLGVLYLCKGLFYRVVPADQRMDTSYAGVFRLHGSYEALKYGSLLDGLAD 68
+GD WL++ + L L LFYRVVP DQ +YAG+F ++ +YG +D + D
Sbjct: 361 LGDCWLLAAVANLTLRDELFYRVVPPDQSFTENYAGIFH----FQFWRYGQWVDVVID 414
>UniRef50_Q16WJ3 Cluster: Calpain; n=2; Culicidae|Rep: Calpain -
Aedes aegypti (Yellowfever mosquito)
Length = 587
Score = 79.4 bits (187), Expect = 2e-13
Identities = 81/322 (25%), Positives = 148/322 (45%), Gaps = 26/322 (8%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVM--PELSDGSALRTLLDTSSVVTAHYFPPV 106
+L+G Y LK+G++ L DLTG + +S+ P L TLL S V
Sbjct: 74 KLYGGYAFLKFGTVGRALQDLTGAVVQSVPPSGPLLGGAVPRSTLLVAISGVEKETKRRR 133
Query: 107 T-IISVFFLSLPTGIRLVKIRLRRSVINIFQVDTTNEPVYLIRLRRPLGHGETP-ISHIV 164
+ ++S S+ TG+ R+R + + Q+ + LIRLR P GE +
Sbjct: 134 SGLLSEHPYSV-TGLA----RVRANSSDSSQISGQSGDTSLIRLRSPWIGGEWGGVWCGA 188
Query: 165 LDTALWKTIPQYERDRLMTASKG-----VWMLFSDFQRLFPRIEMVHLDTETSRAELSLS 219
W+ ERDR + +S+ WM S+F F I + H+ + E L
Sbjct: 189 WSERSWEWNALNERDRELLSSRSSNDCEFWMSVSEFLSRFVVIWLAHIGPDDWALEPGLH 248
Query: 220 EKQKWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQ--VQIMLNEPDT--VIISLNQ---- 271
+ W+ + W+ G +AGG ++ TNPQ +++ P V+++++Q
Sbjct: 249 TRTPWRAALAVRQWRAGFNAGGPHKFIETTATNPQFRIRVPAGHPAKAHVVVAVSQKYEC 308
Query: 272 --HSIMEPKVIGFSVYKMPKFLTETANQMFFKRIKSTINSQYTNSRQVSQRCQLESGAYL 329
E + IGF++Y++P + Q +++ + +N R+++ L +G ++
Sbjct: 309 YRSRNYEDEEIGFTIYEVPPGMQRVTPQYVSEQMPLDF-APLSNLREIATFFALPAGDFV 367
Query: 330 IMPTTFEPREEAQFTLRIYSNK 351
+MP + + R E +F LRI++++
Sbjct: 368 VMPHSQQHR-EGRFLLRIFADQ 388
>UniRef50_Q5TMZ6 Cluster: ENSANGP00000028181; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000028181 - Anopheles gambiae
str. PEST
Length = 538
Score = 74.5 bits (175), Expect = 6e-12
Identities = 93/327 (28%), Positives = 145/327 (44%), Gaps = 34/327 (10%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVMP--ELSD-GSALRTLLDTSSVVTA--HYF 103
+LHGSYEAL G+ +G+ DLTGGITE + E D L + L S++TA +
Sbjct: 204 KLHGSYEALDSGTGREGMVDLTGGITEFYQLKGNEPDDLFERLESNLARRSLITAGINGN 263
Query: 104 PPVTIISVFFLSLPTGIRLVKIRLRRSVINIFQVDTTNE-PVYLIRLRRPLGHGETPISH 162
+ SV + + K+ + +++ N V LI +R P G GE S
Sbjct: 264 ERERVQSVNLVP-QHEYSVTKVTRLDATLHMLDFGAGNAVDVRLICVRNPWGRGEW--SG 320
Query: 163 IVLDTAL-WKTIPQYERDRLMTASKG--VWMLFSDFQRLFPRIEMVHLDTETSRAELSLS 219
D +L W + + + L + WM F DF F + + + E L
Sbjct: 321 AWGDHSLEWIMVRDEKMEELNIVKEDGEFWMNFEDFVHHFDDVSVCYQCPGDMGKE--LR 378
Query: 220 EKQKWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIML-----NEPD---TVIISLNQ 271
+ +M G WKR +AGG N F +NPQ + L E D +V I L Q
Sbjct: 379 ARYPREMVSEMGEWKRSATAGGSDE--NSFWSNPQYVLKLAHHEGYEADSRISVTIGLMQ 436
Query: 272 --HSIMEPKVIGFS--VYKMPKFLTETANQM----FFKR-IKSTINSQYTNSRQVSQRCQ 322
H + V+ +P + T N+ FF I + + +R+V R +
Sbjct: 437 KHHRAKGTSFLSLRLLVFPIPNHVL-TGNRFLPKSFFDNVIPVETEANFETTREVVGRYK 495
Query: 323 LESGAYLIMPTTFEPREEAQFTLRIYS 349
L G Y+++P T++P++EA+F LRI++
Sbjct: 496 LPPGRYVVVPHTWKPQQEAEFMLRIFA 522
>UniRef50_Q4SFI9 Cluster: Chromosome 7 SCAF14601, whole genome
shotgun sequence; n=4; Clupeocephala|Rep: Chromosome 7
SCAF14601, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 656
Score = 73.7 bits (173), Expect = 1e-11
Identities = 74/257 (28%), Positives = 107/257 (41%), Gaps = 42/257 (16%)
Query: 124 KIRLRRSVINIFQVDTTNEPVYLIRLRRPLGHGETPISHIVLDTALWKTIPQYERDRL-- 181
K+RL ++ F+ NE + LIR+R P G E + + W + ER L
Sbjct: 260 KVRLGHGLVAYFK----NETIPLIRMRNPWGKTEWKGAWSD-SSPEWSKVGDTERGNLGI 314
Query: 182 MTASKG-VWMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQKWQMKMHQGGWKRGVS-- 238
A G WM F+D+ + F ++ L TS +S + W +H G W +
Sbjct: 315 TVADDGEFWMSFTDWCKFFTEADVCRL-INTSM----ISVHKTWHEVVHFGSWTKNAEPL 369
Query: 239 ---AGGCRNYVNFFHTNPQVQI--------------MLNEPDTVIISLNQHSIM------ 275
GGC N+ F NPQV + E D ++ISL Q +
Sbjct: 370 LNRCGGCANHRQTFLQNPQVLPPSPALQPIKEYLFDITKEADEMLISLQQKDLKALRKVG 429
Query: 276 --EPKVIGFSVYKMPKFLTETANQMFFKRIKSTINSQYTNSRQVSQRCQLESGAYLIMPT 333
E IGFSV+K+ L ++ + S Y N+R V R L G Y+I PT
Sbjct: 430 QGENLTIGFSVFKVE--LNRKYRMHDILTQEALVTSTYINARSVFLRYTLSLGRYVIFPT 487
Query: 334 TFEPREEAQFTLRIYSN 350
TF P F LR+Y++
Sbjct: 488 TFRPLTLGDFMLRVYTD 504
>UniRef50_Q17E42 Cluster: Calpain, putative; n=1; Aedes aegypti|Rep:
Calpain, putative - Aedes aegypti (Yellowfever mosquito)
Length = 632
Score = 73.3 bits (172), Expect = 1e-11
Identities = 50/170 (29%), Positives = 91/170 (53%), Gaps = 11/170 (6%)
Query: 189 WMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQKWQMKMHQGGWKRGVSAGGCRNYVNF 248
W+ +F F +E+ + T + S++ W ++G W G++AGG +++
Sbjct: 338 WLCIEEFMDRFDGVEICSI-TPDPLGDPEGSQRI-WNTSFYEGIWVSGLTAGGSKDHKVS 395
Query: 249 FHTNPQVQIMLNEPD--TVIISLNQHSIMEPKVIGFSVYKMPKFLTETANQMFFKRIKST 306
+ NP+++I L++PD T + SL S+M+ + G + + F ++N + R T
Sbjct: 396 YGMNPRIRIELSDPDNGTELCSL-VISLMQKQRTGMVLCLVIGFEVLSSNNITVAR---T 451
Query: 307 INSQYTNSRQVSQRCQLESGAYLIMPTTFEPREEAQFTLRIYSNKPLKMK 356
I Y+NSR+VS R QL G+Y I+P+T +P E F LRI++ ++ +
Sbjct: 452 I---YSNSREVSCRLQLPPGSYTIIPSTKQPDENGTFLLRIFTGPQVQQE 498
>UniRef50_Q6ZSI9 Cluster: Calpain-12; n=18; Mammalia|Rep: Calpain-12
- Homo sapiens (Human)
Length = 719
Score = 73.3 bits (172), Expect = 1e-11
Identities = 69/219 (31%), Positives = 96/219 (43%), Gaps = 16/219 (7%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVMPELSDG--SALRTLLDTSSVVTAHYFPPV 106
+LHGSYE ++ G + + D TGG+ E + + + S G SALR L S+V A
Sbjct: 187 KLHGSYEVMRGGHMNEAFVDFTGGVGEVLYLRQNSMGLFSALRHALAKESLVGA------ 240
Query: 107 TIISVFFLSLPTGIRLVKIRLRRSVINIFQVDTTNEPVYLIRLRRPLGHGETPISHIVLD 166
T +S T LVK S+ +V V L+RLR P G E +
Sbjct: 241 TALSDRG-EYRTEEGLVKGHAY-SITGTHKVFLGFTKVRLLRLRNPWGCVEWTGAWSD-S 297
Query: 167 TALWKTIPQYERDRLMTASKG--VWMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQKW 224
W T+P RD L+ + WM DF F +++ L E E W
Sbjct: 298 CPRWDTLPTECRDALLVKKEDGEFWMELRDFLLHFDTVQICSLSPEVLGPS---PEGGGW 354
Query: 225 QMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPD 263
+ QG W RG ++GG + F TNPQ ++ L EPD
Sbjct: 355 HVHTFQGRWVRGFNSGGSQPNAETFWTNPQFRLTLLEPD 393
Score = 54.0 bits (124), Expect = 9e-06
Identities = 65/250 (26%), Positives = 104/250 (41%), Gaps = 41/250 (16%)
Query: 280 IGFSVYKMPKFLT----ETANQMFFKRIKSTINSQYTNSRQVSQRCQLESGAYLIMPTTF 335
+GF V+++P+ L + R+ S + R V++RC L G YL++P+T
Sbjct: 448 VGFHVFQIPEELLGLWDSPRSHALLPRLLRADRSPLSARRDVTRRCCLRPGHYLVVPSTA 507
Query: 336 EPREEAQFTLRIYSNKPLKMKVLDDPPQMTKAALVKAPPGSDSNGFFQYETLFLQLADAH 395
+EA FTLR++S + +DD +A +++ G E LF +LA
Sbjct: 508 HAGDEADFTLRVFSERRHTAVEIDD----VISADLQSLQGPYLPLELGLEQLFQELAGEE 563
Query: 396 RTIDIFELQELLDACL---------PNDY-IKSCVSI---------DTLKHLQ------- 429
++ +LQ LL L P + +++C + L H Q
Sbjct: 564 EELNASQLQALLSIALEPARAHTSTPREIGLRTCEQLLQCFGHGQSLALHHFQQLWGYLL 623
Query: 430 ---LVFKTHAREKMGVLRVERLRDALKDVGFIVPERVISLLVFRYMRKDGMLR--FGDFV 484
+F + G + LR AL GF + ++ L RY +D LR F FV
Sbjct: 624 EWQAIFNKFDEDTSGTMNSYELRLALNAAGFHLNNQLTQTLTSRY--RDSRLRVDFERFV 681
Query: 485 SAVMHLHRVF 494
S V HL +F
Sbjct: 682 SCVAHLTCIF 691
>UniRef50_Q17E39 Cluster: Putative uncharacterized protein; n=1;
Aedes aegypti|Rep: Putative uncharacterized protein -
Aedes aegypti (Yellowfever mosquito)
Length = 292
Score = 71.3 bits (167), Expect = 6e-11
Identities = 59/205 (28%), Positives = 95/205 (46%), Gaps = 25/205 (12%)
Query: 218 LSEKQKWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPDTVIISLNQH---SI 274
LSE WQ+ +G W G +AGG ++ + F TNPQ + L PD + S + H S+
Sbjct: 5 LSEDYSWQLSCIEGSWVSGSTAGGSKDDLKSFWTNPQYLLQLTHPDELDNSDSCHVVISL 64
Query: 275 MEP------KVIGFSVYKMP--KFLTETANQMFFKR--IKSTINSQYTNSRQVSQRCQLE 324
M+ I F V+++P F T+T + K+ K + ++N+R+++ R ++
Sbjct: 65 MQKLHDTGYHPISFVVFQIPDEDFRTKTIPMSYSKKKLPKIIAHPTFSNAREITGRVRIS 124
Query: 325 SGAYLIMPTTFEPREEAQFTLRIYSNKPLKMKVLDDPPQMTKAALVKAPPGSDSNGFFQY 384
LI+P T + E F LRIYS KP + K V + P + +
Sbjct: 125 PSTLLIVPCTQKRNVEGDFFLRIYS-KPHR-----------KDVQVSSMPCTMGTNWSSI 172
Query: 385 ETLFLQLADAHRTIDIFELQELLDA 409
+F +D T+D L +LDA
Sbjct: 173 VRMFYSFSDTLGTVDHAALASILDA 197
>UniRef50_A7RJ84 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 625
Score = 69.3 bits (162), Expect = 2e-10
Identities = 42/130 (32%), Positives = 67/130 (51%), Gaps = 9/130 (6%)
Query: 132 INIFQVDTTNEPVYLIRLRRPLGHGETPISHIVLDTALWKTIPQYERDRL---MTASKGV 188
IN+F +T V LIR+R P G + + W+ + Q E+ L
Sbjct: 178 INVFL--STRGGVELIRIRNPWGDEKEWTGAWGDRSPEWQELSQDEKRSLDLEFDVDGEF 235
Query: 189 WMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQKWQMKMHQGGWKRGVSAGGCRNYVNF 248
WM F DF+ F ++E+ LD E + + +S + ++ G W++ VSAGGCRN++
Sbjct: 236 WMSFEDFKSHFDKLEVCMLDVENAIDKTQIS----FNSRLENGFWRKHVSAGGCRNFLET 291
Query: 249 FHTNPQVQIM 258
FHTNPQ +++
Sbjct: 292 FHTNPQFRLV 301
Score = 59.3 bits (137), Expect = 2e-07
Identities = 49/165 (29%), Positives = 78/165 (47%), Gaps = 14/165 (8%)
Query: 280 IGFSVYKMP-----KFLTETANQMFFKRIKSTINSQYTNSRQVSQRCQLESGAYLIMPTT 334
IGF++YK+ K+ ++ +F+ KST S + NSR+V R +L G Y+I+P+T
Sbjct: 393 IGFALYKIDDITKRKYGVSRLDKEYFQFNKSTERSTFINSREVVGRFELAPGEYVIVPST 452
Query: 335 FEPREEAQFTLRIYSNKPLKMKVLDDPPQMTKAAL--VKAPPGSDSNGF------FQYET 386
F EA F LRI+S K + L + + V +D+ F F E
Sbjct: 453 FIQNAEADFLLRIFSEKAVSSSALTESTFFGSLGIDQVDLKDMNDAEKFRVFFDKFAGEA 512
Query: 387 LFLQL-ADAHRTIDIFELQELLDACLPNDYIKSCVSIDTLKHLQL 430
+F + D +I+ FEL++ L P I +S+ + L L
Sbjct: 513 IFKRYDIDESGSIEAFELRQALFDAYPMLCIALTLSLTIIVELSL 557
Score = 38.7 bits (86), Expect = 0.36
Identities = 25/78 (32%), Positives = 42/78 (53%), Gaps = 6/78 (7%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVMPELSDGSALRTLLDTSSVVTAHYFPPVTI 108
++HGSYEALK G + L D TGG++E V+ + + L ++ + +A + +
Sbjct: 123 KIHGSYEALKGGLTGEALEDFTGGLSEVFVLEDAP--ANLFQIMQRAEKRSALMGCSINV 180
Query: 109 ISVFFLSLPTGIRLVKIR 126
FLS G+ L++IR
Sbjct: 181 ----FLSTRGGVELIRIR 194
>UniRef50_Q9Y6Q1 Cluster: Calpain-6; n=13; Eutheria|Rep: Calpain-6 -
Homo sapiens (Human)
Length = 641
Score = 69.3 bits (162), Expect = 2e-10
Identities = 75/268 (27%), Positives = 120/268 (44%), Gaps = 31/268 (11%)
Query: 124 KIRLRRSVINIFQVDTTNEPVYLIRLRRPLGHGET--PISHIVLDTALWKTIPQYERDRL 181
KIRL ++ +F E VY++RLR PLG E P S I + W+ + +R L
Sbjct: 261 KIRLGERLVEVFSA----EKVYMVRLRNPLGRQEWSGPWSEISEE---WQQLTASDRKNL 313
Query: 182 ---MTASKGVWMLFSDFQRLFPRIEMVHLDTET--SRAELSLSEKQKWQMKMHQGGWKRG 236
M+ WM DF R F ++ + R EL S W + R
Sbjct: 314 GLVMSDDGEFWMSLEDFCRNFHKLNVCRNVNNPIFGRKELE-SVLGCWTVD-DDPLMNR- 370
Query: 237 VSAGGCRNYVNFFHTNPQVQIMLNEPD-TVIISLNQHSIMEPK--------VIGFSVYKM 287
+GGC N + F NPQ + E VI+SL Q + + +IGF ++K+
Sbjct: 371 --SGGCYNNRDTFLQNPQYIFTVPEDGHKVIMSLQQKDLRTYRRMGRPDNYIIGFELFKV 428
Query: 288 PKFLTETANQMFFKRIKSTINSQYTNSRQVSQRCQLESGAYLIMPTTFEPREEAQFTLRI 347
+ ++ + T S Y ++R V L+ G Y+++PT F+ ++F LRI
Sbjct: 429 EMNRKFRLHHLYIQERAGT--STYIDTRTVFLSKYLKKGNYVLVPTMFQHGRTSEFLLRI 486
Query: 348 YSNKPLKMKVLD-DPPQMTKAALVKAPP 374
+S P++++ L D P+M+ L + P
Sbjct: 487 FSEVPVQLRELTLDMPKMSCWNLARGYP 514
>UniRef50_Q6NW69 Cluster: Zgc:85932; n=7; Clupeocephala|Rep:
Zgc:85932 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 671
Score = 67.3 bits (157), Expect = 9e-10
Identities = 71/310 (22%), Positives = 131/310 (42%), Gaps = 23/310 (7%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVMPEL--SDGSALRTLLDTSSVVT-AHYFPP 105
+L G Y AL G + + D+TGGITE ++ L + GS LR+LL+ +++ A+ P
Sbjct: 176 KLKGGYSALNMGFPHEAMVDMTGGITEVFMVASLPRALGSFLRSLLEKGALINCANSQGP 235
Query: 106 VTIISVFFLSLPTGIRLVKIRLRRSVINIFQVDTTNEPVYLIRLRRPLGHGETPISHIVL 165
+ + F GI R SV + V +T PV L+R+R P G E
Sbjct: 236 LEKSNEF------GI---LFRHAYSVTALETVKSTIGPVQLVRIRNPWGKAEWEGPWSDK 286
Query: 166 DTALWKTIPQYER---DRLMTASKGVWMLFSDFQRLFPRIEMVHLDTET-SRAELSLSEK 221
W + E+ R+ WM +DF++ F +E+ HL +T S ++ K
Sbjct: 287 KGIEWHMVTAEEQRRVQRIQQEDGEFWMSLADFRQNFELMEVCHLSEDTLSEGDV----K 342
Query: 222 QKWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPDTVIISLNQHSIMEPKVIG 281
+ W+ H G W G + + + ++ + +H+ ++
Sbjct: 343 KPWKCTSHHGQWT--PLQGSPQYNLTLLEEDDDPSDPELTCSFLLALMQKHTRQRGTLLS 400
Query: 282 FSVYKMPKFLTETANQMFFKRIKSTINSQYTNSRQVSQRCQLESGAYLIMPTTFEPREEA 341
+++ + K + + +T + + ++ R +L G Y+I+P E +
Sbjct: 401 IALH-IYKARDHGVSSRESPLLSTTKDQGFQQRPELVLRSRLAPGHYIIIPAIQETNQSG 459
Query: 342 QFTLRIYSNK 351
+F LR+ + K
Sbjct: 460 EFLLRVLTEK 469
>UniRef50_UPI000065D0F1 Cluster: Homolog of Gallus gallus "Calpain 3
large subunit (EC 3.4.22.-) (Calpain L3) (Calpain p94,
large [catalytic] subunit) (Calcium-activated neutral
proteinase 3) (CANP 3) (Muscle-specific
calcium-activated neutral protease 3 large subunit).;
n=1; Takifugu rubripes|Rep: Homolog of Gallus gallus
"Calpain 3 large subunit (EC 3.4.22.-) (Calpain L3)
(Calpain p94, large [catalytic] subunit)
(Calcium-activated neutral proteinase 3) (CANP 3)
(Muscle-specific calcium-activated neutral protease 3
large subunit). - Takifugu rubripes
Length = 427
Score = 66.5 bits (155), Expect = 2e-09
Identities = 70/301 (23%), Positives = 126/301 (41%), Gaps = 29/301 (9%)
Query: 135 FQVDTTNEPVYLIRLRRPLGHGET--PISHIVLDTALWKTIPQYERDRLMTASKG---VW 189
FQV + L+RLR P G E P S + W + + E++++ K W
Sbjct: 41 FQVLNASVETLLLRLRNPWGFVEYRGPWSDKAKE---WDDVDKAEKEKIELIKKEDGEFW 97
Query: 190 MLFSDFQRLFPRIEMVHLDTETSRAELSLSE-----KQKWQMKMHQGGWKRGVSAGGCRN 244
+ D RLF +E+ ++ +T E + W + H+G W G SAGG R
Sbjct: 98 ISVEDLSRLFDVVELCSVNPDTLTEENPPASPVPPPSSTWTISEHEGFWVPGSSAGGSRK 157
Query: 245 YVNFF------HTNPQVQIMLNEPDTVIISLNQHSIMEPKVIGFS--VYKMPKFLTETAN 296
Y + + + ++ TV++ L Q + + + F + + KF +
Sbjct: 158 YKHDSDEETAKEERAEKRKQKSKRCTVLVELLQKNRRQRDKVHFLYIAFHVYKFQSACLT 217
Query: 297 QMFFKRIKSTINS-QYTNSRQVSQRCQLESGAYLIMPTTFEPREEAQFTLRIYSNKPLKM 355
+ FF + S +Y R V ++ L+ G Y+++ +T+ P + +F +RI+S +
Sbjct: 218 RSFFMKNSPVGRSGKYRAQRGVWRKLLLDPGRYIVVASTYRPNQSGEFFVRIFSKTGNTL 277
Query: 356 K------VLDDPPQMTKAALVKAPPGSDSNGFFQYETLFLQL-ADAHRTIDIFELQELLD 408
D P +A+L + + Q + +F Q D+ T+ FEL L+
Sbjct: 278 GKNDFSCSFDFLPTKGRASLSRKQAETLLTSLRQLQAIFFQFDEDSSGTMSPFELSAALE 337
Query: 409 A 409
A
Sbjct: 338 A 338
>UniRef50_Q9HC96 Cluster: Calpain-10; n=35; Amniota|Rep: Calpain-10
- Homo sapiens (Human)
Length = 672
Score = 63.3 bits (147), Expect = 1e-08
Identities = 77/344 (22%), Positives = 136/344 (39%), Gaps = 38/344 (11%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVMPELSDGSALRTLLDTSSVVTAH---YFPP 105
++HGSYE L G + D L DLTGG+ E + ++ + T +
Sbjct: 157 KVHGSYEHLWAGQVADALVDLTGGLAERWNLKGVAGSGGQQDRPGRWEHRTCRQLLHLKD 216
Query: 106 VTIISVFFLSLPTGIRLVKIRLRRSVINIFQVD-TTNEPVYLIRLRRPLGHGETPISHIV 164
+IS LS G R + V ++ ++ + + L+R++ P G
Sbjct: 217 QCLISCCVLSPRAGARELGEFHAFIVSDLRELQGQAGQCILLLRIQNPWGRRCWQGLWRE 276
Query: 165 LDTALWKTIPQYERDRLMTA-SKG-VWMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQ 222
W + L++ +G W+ +F R F + + + TE + +E+
Sbjct: 277 GGEG-WSQVDAAVASELLSQLQEGEFWVEEEEFLREFDELTVGYPVTEAGHLQSLYTERL 335
Query: 223 KWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPDTVIISLNQ----------- 271
+ G W +G SAGGCRN F +NP+ + ++EP V I++ Q
Sbjct: 336 LCHTRALPGAWVKGQSAGGCRNNSGF-PSNPKFWLRVSEPSEVYIAVLQRSRLHAADWAG 394
Query: 272 ---------HSIMEP--------KVIGFSVYKMPKFLTETANQMFFKRIKSTINSQYTNS 314
H+ P + +G ++K+ K + + T Y
Sbjct: 395 RARALVGDSHTSWSPASIPGKHYQAVGLHLWKVEKRRVNLPRVLSMPPVAGTACHAY--D 452
Query: 315 RQVSQRCQLESGAYLIMPTTFEPREEAQFTLRIYSNKPLKMKVL 358
R+V RC+L G YL +P+TF +F LR++S + + +
Sbjct: 453 REVHLRCELSPGYYLAVPSTFLKDAPGEFLLRVFSTGRVSLSAI 496
Score = 60.1 bits (139), Expect = 1e-07
Identities = 41/133 (30%), Positives = 73/133 (54%), Gaps = 11/133 (8%)
Query: 223 KWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNE---PDTVIISLNQH---SIME 276
+W +G W+ G +AGG RN+ ++ TNP + E P V I+L+QH S E
Sbjct: 513 EWGTVQLRGSWRVGQTAGGSRNFASY-PTNPCFPFSVPEGPGPRCVRITLHQHCRPSDTE 571
Query: 277 PKVIGFSVYKMPKF-LTETANQMFFKR-IKSTINSQYTNSRQVSQRCQLESGAYLIMPTT 334
IGF ++++P+ ++ A + + + S + +Y +++VS+ C L +G Y ++P+T
Sbjct: 572 FHPIGFHIFQVPEGGRSQDAPPLLLQEPLLSCVPHRY--AQEVSRLCLLPAGTYKVVPST 629
Query: 335 FEPREEAQFTLRI 347
+ P E FT+ I
Sbjct: 630 YLPDTEGAFTVTI 642
>UniRef50_Q32NI7 Cluster: LOC733407 protein; n=2; Xenopus|Rep:
LOC733407 protein - Xenopus laevis (African clawed frog)
Length = 654
Score = 62.5 bits (145), Expect = 3e-08
Identities = 82/325 (25%), Positives = 135/325 (41%), Gaps = 34/325 (10%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVMPELSDGSALRTLLDTSSVVTAHYFPPVTI 108
+LHG YEAL G + D L DLTGG+ E + D S L S +V+
Sbjct: 164 KLHGCYEALWAGQVADALVDLTGGLVERWFLGS-EDESGREKLF--SKLVSLK-----DR 215
Query: 109 ISVFFLSLPTGIRLVKIRLRRS--VINIFQVDTTN-EPVYLIRLRRPLGHGETPISHIVL 165
++ L R+V++ + + +I V T + + L+RL P G S
Sbjct: 216 CAMCCSVLHNRERVVELGEPHAYTITDIQHVVTKGCKDLLLLRLHNPWGRSSWAGSWCKG 275
Query: 166 DTALWKTIPQYERDRLMTA-SKG-VWMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQK 223
D W + + +L++ +G W+ +F + F + + + + ++
Sbjct: 276 DDG-WNDLDPKDSTQLLSGVQEGEFWVEKQEFLQEFDEVTIAFPCSHEGHLQSIWTDSLL 334
Query: 224 WQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPDTVIISLNQ--HSIMEPKVIG 281
+ G W +G SAGG RN + F NP+ + + EP V +SL Q H +E
Sbjct: 335 LYKQQIYGSWVKGHSAGGSRNNIT-FSENPKFWLRVKEPSEVFLSLMQIPHGGVEIPEPV 393
Query: 282 FSVYKMPKFLTETA-NQMFFK---------RIKSTIN-------SQYTNSRQVSQRCQLE 324
VY+ L TA N + F +++ T++ S + RQ+ C L
Sbjct: 394 HGVYRRNLRLNRTAFNAVGFHVWKVEKRRFKLQKTLSSLPLAGTSSHCYDRQLHLCCNLS 453
Query: 325 SGAYLIMPTTFEPREEAQFTLRIYS 349
G +L++P+ F E F L I S
Sbjct: 454 PGYHLLIPSIFLREAEGNFLLHILS 478
Score = 57.2 bits (132), Expect = 1e-06
Identities = 37/126 (29%), Positives = 66/126 (52%), Gaps = 7/126 (5%)
Query: 224 WQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNE--PDTVIISLNQHSIMEPKVIG 281
W+ + +G WK+G +AGG RN+ + + NP + + P + QHS + IG
Sbjct: 505 WETQELRGQWKKGSNAGGSRNF-DSYTINPCFPFSVPDGAPQIRLTLRQQHSGEKCHAIG 563
Query: 282 FSVYKMPKFLTETANQMFFKRIKSTINSQYTNSRQVSQRCQLESGAYLIMPTTFEPREEA 341
F VY + + +N + +K +S + ++VS+ C L G Y ++P+T+ P +E+
Sbjct: 564 FHVYSVTSNESVISNSLE-PCVKCIPHS---HCQEVSKLCVLPPGQYTLVPSTYLPDQES 619
Query: 342 QFTLRI 347
FT+ I
Sbjct: 620 NFTVTI 625
>UniRef50_Q8RVL2 Cluster: Calpain-like protein; n=16;
Magnoliophyta|Rep: Calpain-like protein - Arabidopsis
thaliana (Mouse-ear cress)
Length = 2151
Score = 61.3 bits (142), Expect = 6e-08
Identities = 86/339 (25%), Positives = 140/339 (41%), Gaps = 56/339 (16%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESI------VMPELSDGSALRTLL--DTSSVVTA 100
+LHGSYEAL+ G + D L DLTGG E I +L+ G LL +
Sbjct: 1840 KLHGSYEALEGGLVQDALVDLTGGAGEEIDLRSAQAQIDLASGRLWSQLLRFKQEGFLLG 1899
Query: 101 HYFPPVTIISVFFLSLPTGIRLVKIRLRRSVINIFQVDTTNEPVYLIRLRRPLGHGETPI 160
P + + V + G SV+ + +VD L+++R P + E
Sbjct: 1900 AGSPSGSDVHVSSSGIVQGHAY-------SVLQVREVDGHR----LVQIRNPWAN-EVEW 1947
Query: 161 SHIVLDTA-LWKTIPQYERDRLMTASKGV-WMLFSDFQRLFPRIEMVHLDTETSRAELSL 218
+ D++ W +++ + + +G+ WM + DFQ F I + + R ++
Sbjct: 1948 NGPWSDSSPEWTDRMKHKLKHVPQSKEGIFWMSWQDFQIHFRSIYVCRVYPREMRYSVN- 2006
Query: 219 SEKQKWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPDT-----VIISLNQHS 273
G W RG SAGGC++Y + +H NPQ ++ D V I+L Q
Sbjct: 2007 ------------GQW-RGYSAGGCQDY-SSWHQNPQFRLRATGSDASLPIHVFITLTQGV 2052
Query: 274 IMEPKVIGFSVYKMP----------KFLTETANQMFFKRI--KSTINSQYTNSRQVSQRC 321
GF Y+ + L + + +S + Y NSR++S
Sbjct: 2053 GFSRTTPGFRNYQSSHDSQLFYIGLRILKTRGRRAAYNIFLHESVGGTDYVNSREISCEM 2112
Query: 322 QLESG--AYLIMPTTFEPREEAQFTLRIYSNKPLKMKVL 358
L+ Y I+PTT P EEA F L +++ + ++ L
Sbjct: 2113 VLDPDPKGYTIVPTTIHPGEEAPFVLSVFTKASIVLEAL 2151
>UniRef50_UPI0000EB2C11 Cluster: Calpain-11 (EC 3.4.22.-)
(Calcium-activated neutral proteinase 11) (CANP 11).;
n=1; Canis lupus familiaris|Rep: Calpain-11 (EC
3.4.22.-) (Calcium-activated neutral proteinase 11)
(CANP 11). - Canis familiaris
Length = 752
Score = 58.0 bits (134), Expect = 6e-07
Identities = 35/99 (35%), Positives = 59/99 (59%), Gaps = 4/99 (4%)
Query: 311 YTNSRQVSQRCQLESGAYLIMPTTFEPREEAQFTLRIYSNKPLKMKVLDDPPQMTKAALV 370
+TNSR+VS QL G Y+I+P+TFEP ++A F LR+++ K + LD + A L+
Sbjct: 514 FTNSREVSSHLQLPPGEYVIIPSTFEPHKDADFLLRVFTEKHSESWELD---EANYAELL 570
Query: 371 KAPPGSDSNGFFQYETLFLQLADAH-RTIDIFELQELLD 408
+ S+++ + LF +A + I ++ELQ+LL+
Sbjct: 571 QEEHFSENDVDQDFIHLFEIVAGGEGKEIGMYELQKLLN 609
Score = 43.2 bits (97), Expect = 0.017
Identities = 37/111 (33%), Positives = 56/111 (50%), Gaps = 7/111 (6%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVM--PELSDGSALRTLLDTSSVVTAHYFPPV 106
+L+GSYEAL GS ++G D TGG+T +I + P + LR ++ SS++ +
Sbjct: 239 KLNGSYEALSGGSTVEGFEDFTGGVTYTIQLQKPPRNLLRMLRKAVERSSLMGC----SI 294
Query: 107 TIISVFFLSLPTGIRLVKIRLRRSVINIFQVDTTNEPVYLIRLRRPLGHGE 157
I+S L T LV+ SV ++ +V LIR+R P G E
Sbjct: 295 EIVSESELETMTQKMLVRGH-AYSVTDLQEVWYQGRTETLIRVRNPWGRVE 344
Score = 42.3 bits (95), Expect = 0.029
Identities = 20/58 (34%), Positives = 33/58 (56%), Gaps = 4/58 (6%)
Query: 11 VGDKWLVSCLGVLYLCKGLFYRVVPADQRMDTSYAGVFRLHGSYEALKYGSLLDGLAD 68
+GD WL++ +G L C L +RVVP Q +YAG+F ++ ++G +D + D
Sbjct: 154 LGDCWLLAAIGSLTTCPKLLHRVVPKGQSFRKNYAGIFH----FQFWQFGQWVDVVVD 207
Score = 34.7 bits (76), Expect = 5.9
Identities = 17/64 (26%), Positives = 32/64 (50%)
Query: 431 VFKTHAREKMGVLRVERLRDALKDVGFIVPERVISLLVFRYMRKDGMLRFGDFVSAVMHL 490
+F+ + G L +R A++ G + +V +LV RY +D ++ F F+S + L
Sbjct: 661 IFRECDEDHSGSLNSYEMRLAIEKAGIKLSNKVTQVLVARYSNEDMIVDFDSFISCFLRL 720
Query: 491 HRVF 494
+F
Sbjct: 721 KAMF 724
>UniRef50_Q4RQ29 Cluster: Chromosome 17 SCAF15006, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 17 SCAF15006, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 575
Score = 56.4 bits (130), Expect = 2e-06
Identities = 45/134 (33%), Positives = 60/134 (44%), Gaps = 28/134 (20%)
Query: 130 SVINIFQVDTTNEPVYLIRLRRPLGHGETPISHIVLDTALWKTIPQYERDRLMTASKGVW 189
SV +FQV E V LIR+R P G E T W S G
Sbjct: 192 SVPFVFQVSYRGEQVQLIRVRNPWGQVEW--------TGAW--------------SDG-- 227
Query: 190 MLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQKWQMKMHQGGWKRGVSAGGCRNYVNFF 249
M FSDF R F ++E+ +L +T L + W ++G W+ G +AGGC NY F
Sbjct: 228 MSFSDFTRQFSQLEICNLTPDT----LESDDVGHWNHYQYEGAWRVGSTAGGCLNYAATF 283
Query: 250 HTNPQVQIMLNEPD 263
+NPQ + L + D
Sbjct: 284 TSNPQFLVHLEDVD 297
Score = 48.4 bits (110), Expect = 4e-04
Identities = 20/54 (37%), Positives = 33/54 (61%)
Query: 307 INSQYTNSRQVSQRCQLESGAYLIMPTTFEPREEAQFTLRIYSNKPLKMKVLDD 360
++S + N+R+V R L G Y I+P+TF+P + F LR++S K K L++
Sbjct: 443 MSSAFINTREVCDRFTLPPGEYAIVPSTFQPHKNGSFILRVFSEKQAKTSPLEE 496
Score = 37.1 bits (82), Expect = 1.1
Identities = 18/47 (38%), Positives = 28/47 (59%), Gaps = 2/47 (4%)
Query: 11 VGDKWLVSCLGVLYLCKGLFYRVVPADQRMDTSYAGV--FRLHGSYE 55
+GD WL++ + L L + + RVVP DQ YAG+ F++ +YE
Sbjct: 102 LGDCWLLAAIASLTLDQRILARVVPPDQTFAEDYAGIFHFQITSAYE 148
>UniRef50_Q22036 Cluster: Calpain-5; n=2; Caenorhabditis|Rep:
Calpain-5 - Caenorhabditis elegans
Length = 648
Score = 56.4 bits (130), Expect = 2e-06
Identities = 55/179 (30%), Positives = 76/179 (42%), Gaps = 10/179 (5%)
Query: 189 WMLFSDFQRLFPRIEMVHLDTETSRAELSLS-EKQKWQMKMHQGGWKRGVS---AGGCRN 244
WM + F F I + L TS S S ++Q + G K G AGGC N
Sbjct: 334 WMPWESFVHYFTDISLCQL-FNTSVFSFSRSYDEQIVFSEWTTNGKKSGAPDDRAGGCHN 392
Query: 245 YVNFFHTNPQVQIMLNEPD-TVIISLNQHSIME--PKVIGFSVYKMPKFLTETANQMFFK 301
+ F NPQ + P+ +V+ +L Q+ E K F M E Q
Sbjct: 393 FKATFCNNPQYIFDIPSPNCSVMFALIQNDPSEGLKKREPFVTIGMHVMKVENNRQYRVH 452
Query: 302 RIKSTIN-SQYTNSRQVSQRCQ-LESGAYLIMPTTFEPREEAQFTLRIYSNKPLKMKVL 358
I S Y + R V Q L G YL++PTTF P+E+ F LR+YS++ + L
Sbjct: 453 TAMHPIAISDYASGRSVYLHLQSLPRGRYLLIPTTFAPKEQTLFMLRVYSDEHIHFSPL 511
>UniRef50_Q55FS2 Cluster: Calpain-like cysteine protease; n=1;
Dictyostelium discoideum AX4|Rep: Calpain-like cysteine
protease - Dictyostelium discoideum AX4
Length = 1105
Score = 54.8 bits (126), Expect = 5e-06
Identities = 43/146 (29%), Positives = 63/146 (43%), Gaps = 14/146 (9%)
Query: 209 TETSRAELSLSEKQKWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPDTVIIS 268
T +S L +S G W G SAGGC N + NPQ + + T+ I+
Sbjct: 534 TSSSSLPLPMSPSVYLSPTRVSGIWS-GESAGGCAN-TTLWRKNPQYLLQITATTTIRIT 591
Query: 269 LNQHSIMEPKVIGFSVYKMPKFLTETANQMFFKRIKST-------INSQYTNSRQVSQRC 321
L Q K++ Y AN F +RI T ++ + S +VS +
Sbjct: 592 LRQTG---DKLVHIGFYFARS--NTGANDQFRRRITLTKEYLVPGLDITFLKSTEVSAKI 646
Query: 322 QLESGAYLIMPTTFEPREEAQFTLRI 347
+E G Y+I+P TFEP +E F L +
Sbjct: 647 TMEPGYYVIIPATFEPNQEGSFELDV 672
Score = 52.0 bits (119), Expect = 4e-05
Identities = 43/142 (30%), Positives = 68/142 (47%), Gaps = 11/142 (7%)
Query: 215 ELSLSEKQKWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQI--MLNEPDTVIISLNQH 272
+L LSE Q+ G W RG ++GGC N+ + N Q I + P V I L Q
Sbjct: 832 KLDLSE----QILTVHGEW-RGATSGGCLNHTTW-RNNAQYLIHNTSSSPTKVTIMLEQL 885
Query: 273 SIMEPKVIGFSVYKMPKFLTETANQMFFKRIKSTI--NSQYTNSRQVSQRCQLESG-AYL 329
M+ + + F + + K T ++ F I N+++ N QV +E +Y+
Sbjct: 886 EKMDNQQLPFVGFYVAKSPTPNLDKKLFSLTPKDIVGNTEFINDYQVHFTSIMEPNTSYI 945
Query: 330 IMPTTFEPREEAQFTLRIYSNK 351
I+P+TF P E F LR+ +N+
Sbjct: 946 IIPSTFTPGIEYPFNLRVITNQ 967
Score = 49.2 bits (112), Expect = 3e-04
Identities = 44/147 (29%), Positives = 71/147 (48%), Gaps = 15/147 (10%)
Query: 212 SRAELSLSE---KQKWQMKMHQGGWKRGVSAGGCRNYVNF-FHTNPQVQIMLNEPDTVII 267
S + LSE + W++ + W RG SAGG + + + NP+ + I
Sbjct: 685 SNNNIKLSEIKGDRDWRIISDRFEW-RGSSAGGSFSGSSATWKDNPKFFFETTQTSNTTI 743
Query: 268 SLNQHS-IMEPKVIGFSVYKMPK---FLTETANQMFFKRIKSTINSQYTNSRQVSQRCQL 323
L + S I + IGF ++K K F++ TAN ++ K S +N V + Q+
Sbjct: 744 VLGKLSDIPKETYIGFYIFKADKNCPFISLTANNLYSKT--SFVNG----IEVVHTQQQM 797
Query: 324 ESGAYLIMPTTFEPREEAQFTLRIYSN 350
G Y+I+P T++ R+E FTL YS+
Sbjct: 798 PPGCYIIVPCTYDSRQEGSFTLTCYSD 824
Score = 35.1 bits (77), Expect = 4.4
Identities = 33/136 (24%), Positives = 53/136 (38%), Gaps = 12/136 (8%)
Query: 216 LSLSEKQKWQMKMHQGGWKRGVSAGG-CRNYVNFFHTNPQVQIMLNEPDTVIISLNQHSI 274
+ +S +W + G W RG S GG N + + NP+ + L I L Q
Sbjct: 971 IQISRLPEWSTRKLSGEW-RGQSCGGRYSNTSSSWTLNPRFRFNLPRGGRFTIILAQAE- 1028
Query: 275 MEPKVIGFSVYKMPKFLTETANQMFFKRIKSTINSQYTNSRQVSQRCQLESGAY-LIMPT 333
+P G Y T + K S + +++ + G +++P+
Sbjct: 1029 -KPSYNGIGFYYFKTLQDGTLREFVCK-------SGFICGKEIVLESSINEGVTGVVIPS 1080
Query: 334 TFEPREEAQFTLRIYS 349
TFEP + F L IYS
Sbjct: 1081 TFEPNIQDSFNLTIYS 1096
>UniRef50_Q4SWM0 Cluster: Chromosome undetermined SCAF13608, whole
genome shotgun sequence; n=1; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF13608,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 354
Score = 54.0 bits (124), Expect = 9e-06
Identities = 33/99 (33%), Positives = 52/99 (52%), Gaps = 5/99 (5%)
Query: 280 IGFSVYKMPKF-LTETANQMFFKRI--KSTINSQYTNSRQVSQRCQLESGAYLIMPTTFE 336
IGF ++K+ L N+++ + + S Y NSR V +R L G Y+++PTTFE
Sbjct: 133 IGFDIHKVWLCRLQVELNRVYRMHVAQQKVGGSVYINSRSVFKRTDLTEGRYVVIPTTFE 192
Query: 337 PREEAQFTLRIYSNKPLKMK--VLDDPPQMTKAALVKAP 373
P E F LR++++ P + LD+PP + L P
Sbjct: 193 PGLEGDFLLRVFTDVPSHCQELTLDEPPPTCWSGLCGFP 231
>UniRef50_Q4S467 Cluster: Chromosome undetermined SCAF14743, whole
genome shotgun sequence; n=4; Euteleostomi|Rep:
Chromosome undetermined SCAF14743, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 922
Score = 54.0 bits (124), Expect = 9e-06
Identities = 38/128 (29%), Positives = 59/128 (46%), Gaps = 9/128 (7%)
Query: 231 GGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPDTVIISLNQHSIMEPKVIGFSVYKMPKF 290
G WK G+SAGGC NY + + NP Q+ L P ++I L +GF + +
Sbjct: 803 GQWK-GLSAGGCGNYKDSYKHNPIYQVNLERPGPLLIELRG---SRQYSVGFEMVTV-ST 857
Query: 291 LTETANQMFFKRIKSTINSQYTNSRQVSQRCQLESGAYLIMPTTFEPREEAQFTLRIYSN 350
+ + + F K+ + Y + + +G Y + PTTF P++E F L S
Sbjct: 858 VGDPGSSTFHKK----NSGDYRCGFCYMEVEHVPAGIYNVTPTTFLPKQEGPFFLDFAST 913
Query: 351 KPLKMKVL 358
PLK+ L
Sbjct: 914 SPLKVSQL 921
>UniRef50_Q66JI2 Cluster: Calpb protein; n=5; Xenopus|Rep: Calpb
protein - Xenopus tropicalis (Western clawed frog)
(Silurana tropicalis)
Length = 763
Score = 53.6 bits (123), Expect = 1e-05
Identities = 59/246 (23%), Positives = 106/246 (43%), Gaps = 25/246 (10%)
Query: 130 SVINIFQVDTTNEPVYLIRLRRPLGHGETPISHIVLDTALWKTIPQYERDRLMTASKG-- 187
+V + QV+ N L+R+ P G GE + W + R +L
Sbjct: 264 TVTDATQVEYKNGTEDLVRVWNPWGKGEWN-GRWSDNAPQWDRVRADVRQKLNVQKNDGE 322
Query: 188 VWMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQKWQMKMHQGGWKRGVSAGGCRNYVN 247
WM DF + F + T + K+ WQ + W RG +A GC + +
Sbjct: 323 FWMSCQDFLQNF---SCASICNHTPAYFDFDNPKRTWQTLTYFSRWVRGSTAAGCSSKED 379
Query: 248 FFHTNPQVQIMLNEPD------TVIISL-----NQHSIMEPKV-IGFSVYKMPKFLTETA 295
+ NPQ I +++ + V ++L N+H + + IGF++ ++ +
Sbjct: 380 LWR-NPQFVISVSDSEGMKRGYNVTVALMQSLENEHKYSQRWMGIGFALCRVASMGVKGI 438
Query: 296 NQMFF--KRIKSTINSQYTNSRQVSQRCQLESGAYLIMPTTFEPREEAQFTLRIYSNKPL 353
+Q + K+ IN++ SR+V++ G Y+++P T +E++F LRI+ L
Sbjct: 439 SQQNYSAKQAMDVINTEIQISREVTRSFMAPPGTYVVIPFTESKGQESEFLLRIF----L 494
Query: 354 KMKVLD 359
K K +D
Sbjct: 495 KTKEID 500
>UniRef50_UPI0000F1E7D5 Cluster: PREDICTED: hypothetical protein;
n=4; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 929
Score = 51.6 bits (118), Expect = 5e-05
Identities = 45/159 (28%), Positives = 74/159 (46%), Gaps = 24/159 (15%)
Query: 221 KQKWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIML-NEPDTVIISLNQHSIM---- 275
+ +W+M++ R GGC N+ + F NPQ L + V+I L Q
Sbjct: 641 EMRWEMQID-----RRTRCGGCINHRDTFLHNPQFLFELFGGGEEVLICLQQEDRRMKRR 695
Query: 276 ----EPKVIGFSVYKMPK--------FLTETANQMFFKRI--KSTINSQYTNSRQVSQRC 321
E IGF V + + FL N++ + + T +S Y +SR V+ R
Sbjct: 696 EGSGENLPIGFEVLRTARYNVSSYFAFLQVEVNRVCRVQCLCEQTASSVYMDSRSVTLRV 755
Query: 322 QLESGAYLIMPTTFEPREEAQFTLRIYSNKPLKMKVLDD 360
L G Y+I+PTTF+P +F LR +S+ ++++ L +
Sbjct: 756 TLGPGRYVILPTTFQPGATGRFLLRFFSHSHVRLRELKE 794
Score = 40.7 bits (91), Expect = 0.089
Identities = 65/243 (26%), Positives = 104/243 (42%), Gaps = 34/243 (13%)
Query: 11 VGDKWLVSCLGVLYLCKGLFYRVVPADQRMDTSYAGVFRLHGSYEALKYGSLLDGLADLT 70
V D+ VS G L C+ R + ++ +YA +L+G YEAL+ G+ + L D T
Sbjct: 326 VDDRLPVSGDGTLLFCRSATPREFWS-ALLEKAYA---KLNGCYEALEGGNTAEALVDFT 381
Query: 71 GGITE--SIVMPELSDGSALRTLL--------DTSSVVTAHYFPP--VTIISVFFLSL-- 116
GG++E S+ EL S R +L +++T P + SV L
Sbjct: 382 GGVSEPLSLNQEELIQHSDHRKILFQTLAHAHSHKALITCSIRPAEGEALESVLDCGLIK 441
Query: 117 --PTGIRLVKIRLRRSVINIFQVDTTNEPVYLIRLRRPLGHGETPISHIVLDTALWKTIP 174
G+ VK +LR S + + +Y++R+R P G + L + W+
Sbjct: 442 GHAYGVTAVK-KLRMSETLHSMCNASR--LYMVRIRNPWGTTDW-TGAWGLGSPEWQQFN 497
Query: 175 QYERDRLMTASKGV---WMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQK-WQMKMHQ 230
+ E++++ + V WM F DF R F + + L AE SL Q W+
Sbjct: 498 RKEKEKMGLIVRDVGEFWMEFEDFCRYFTDMVVCRL------AEKSLLWPQSHWREVCCH 551
Query: 231 GGW 233
G W
Sbjct: 552 GAW 554
>UniRef50_Q4ST20 Cluster: Chromosome undetermined SCAF14317, whole
genome shotgun sequence; n=2; Tetraodontidae|Rep:
Chromosome undetermined SCAF14317, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 675
Score = 50.0 bits (114), Expect = 1e-04
Identities = 37/112 (33%), Positives = 57/112 (50%), Gaps = 10/112 (8%)
Query: 254 QVQIMLNEPDTVIISLNQHSIMEPKVIGFSVYKMPKFLTETANQMFFKRIKS-TINSQYT 312
+V I L + D I +H E IGF V K+ E +R++ +S Y
Sbjct: 439 EVLICLQQEDRRIH--RKHGGGENLPIGFEVLKV-----EVNRSSRVQRVEEKAASSVYM 491
Query: 313 NSRQVSQRCQLESGAYLIMPTTFEPREEAQFTLRIYSNKPLKMKVL--DDPP 362
+SR V+ R L G Y+I+PTTF P +F LR++ + P++++ L D PP
Sbjct: 492 DSRSVTLRAALAPGRYVILPTTFLPGATGRFLLRVFCHAPVRLRELREDLPP 543
Score = 38.3 bits (85), Expect = 0.48
Identities = 29/78 (37%), Positives = 42/78 (53%), Gaps = 8/78 (10%)
Query: 11 VGDKWLVSCLGVLYLCKGLFYRVVPADQRMDTSYAGVFRLHGSYEALKYGSLLDGLADLT 70
V D+ VS GVL C+ R + ++ +YA +L+G YEAL+ G+ + L D T
Sbjct: 157 VDDRLPVSGDGVLLFCRSATPREFWS-ALLEKAYA---KLNGCYEALEGGNTTEALIDFT 212
Query: 71 GGITESIVMPELSDGSAL 88
GG++E P DG AL
Sbjct: 213 GGVSE----PLRLDGGAL 226
>UniRef50_Q55BR8 Cluster: Calpain-like cysteine protease; n=2;
Dictyostelium discoideum|Rep: Calpain-like cysteine
protease - Dictyostelium discoideum AX4
Length = 649
Score = 48.0 bits (109), Expect = 6e-04
Identities = 37/141 (26%), Positives = 67/141 (47%), Gaps = 8/141 (5%)
Query: 225 QMKMHQGGWKRGVSAGGCRNYVNFFHTNPQ--VQIMLNEPDTVI-ISLNQHSIMEPKVIG 281
+++ +G W G SAGG N FF+ NPQ +++ ++ D VI + L Q S + + IG
Sbjct: 498 EVEQVKGTWV-GKSAGGSPNQPTFFN-NPQFHLKVPASDKDEVIAVQLIQDSTIADEGIG 555
Query: 282 FSVYKMPKFLTETANQMFFKRIKSTINSQYTNSRQVSQRCQLESGA---YLIMPTTFEPR 338
F V Q F + T S + + R ++ + + I+P+TF+P
Sbjct: 556 FIVLSRDSHSEPLTAQDFQNEMVFTKTSNWEKRNDIVCRLHVKPESPREFTIIPSTFDPS 615
Query: 339 EEAQFTLRIYSNKPLKMKVLD 359
F L++YS+ + + ++
Sbjct: 616 VNRSFKLQVYSDVSISLDEIE 636
Score = 39.1 bits (87), Expect = 0.27
Identities = 31/135 (22%), Positives = 59/135 (43%), Gaps = 7/135 (5%)
Query: 216 LSLSEKQKWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPDTVIISLNQHSIM 275
L S++Q W G W + GG N + + NPQ L + + L+Q
Sbjct: 356 LPKSQEQAWNEITVDGLWTTATNGGGDINILGWTK-NPQYSFTLTKKSRACVLLSQDD-- 412
Query: 276 EPKVIGFSVYKMPKFLTETANQMFFKRIKSTINSQYTNSRQVSQRCQLESGAYLIMPTTF 335
K +GF V K F +++ T + +++ S + L+ G Y+++P+T+
Sbjct: 413 NDKSVGFYVIKQLDAGKRAIE--FREQVGKTESFKFSCSTGCT--LTLDEGTYIVIPSTY 468
Query: 336 EPREEAQFTLRIYSN 350
+ E F L ++++
Sbjct: 469 DHGIEGAFHLTLFTD 483
>UniRef50_UPI0000F2B702 Cluster: PREDICTED: hypothetical protein;
n=1; Monodelphis domestica|Rep: PREDICTED: hypothetical
protein - Monodelphis domestica
Length = 624
Score = 46.0 bits (104), Expect = 0.002
Identities = 58/218 (26%), Positives = 91/218 (41%), Gaps = 11/218 (5%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVM--PELSDGSALRTLLDTSSVVTAHYFPPV 106
+LHGSY L GSL D L +LTG I +I + +L+ L+ S++T V
Sbjct: 262 KLHGSYSNLHSGSLADSLVELTGWIVTAIDLKKADLNMVQNLKVAEQCGSIITCG-IENV 320
Query: 107 TIISVFFLSLPTGIRLVKIRLRRSVINIFQVDTTNEPVYLIRLRRPLGHG-ETPISHIVL 165
+ S + LV +V +V P LI+L P G G E +
Sbjct: 321 SSRSEMEQAEALQFGLVN-NHAYAVTGTAEVHLGTGPEELIQLWNPWGWGCEEWLGRWSD 379
Query: 166 DTALWKTIPQYERDRLMT--ASKGVWMLFSDFQRLFPRIEMVHLD-TETSRAELSLSEKQ 222
+ W I ER RL + A WM F DFQ F I + + + E + +L+
Sbjct: 380 KSEEWWKIQDSERTRLYSNKADGEFWMSFQDFQMKFSHIYICYQEPMELNNGDLTNGTWI 439
Query: 223 KWQMKMHQGGWKRGVSAGGCRNYVNF-FHTNPQVQIML 259
+ K+ + + ++ GG + F H +P+ + L
Sbjct: 440 QIPCKVQK--IQENINPGGSSGSLPFRLHYSPESECFL 475
>UniRef50_UPI0000499EFD Cluster: protein kinase; n=1; Entamoeba
histolytica HM-1:IMSS|Rep: protein kinase - Entamoeba
histolytica HM-1:IMSS
Length = 978
Score = 45.2 bits (102), Expect = 0.004
Identities = 36/140 (25%), Positives = 71/140 (50%), Gaps = 10/140 (7%)
Query: 212 SRAELSLSEKQKWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPDTVIISL-- 269
S +++S+S+ + G W ++AGGC N N+ N Q + + E VI L
Sbjct: 746 SMSDISMSQHIPTKTSWISGEWNE-LTAGGCFNSGNW-RKNQQFVLRVKENTRVIAELVY 803
Query: 270 NQHSIMEPKVIGFSVYKMPKFLTETANQMF-FKRIKSTINSQYTNSRQVSQRCQLESGAY 328
++ S + +G ++ K T++ ++F F+ + ++ +TN+ +S+ +L G Y
Sbjct: 804 DKGSPEDKMSMGMTMIK-----TDSNTKIFGFEYQQVVFSTNFTNASYMSKAVELVPGQY 858
Query: 329 LIMPTTFEPREEAQFTLRIY 348
+I+P T P +FT+ I+
Sbjct: 859 VIIPMTILPNLFGKFTIVIH 878
Score = 44.4 bits (100), Expect = 0.007
Identities = 38/153 (24%), Positives = 70/153 (45%), Gaps = 6/153 (3%)
Query: 231 GGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPDTVIISLNQHSIMEPKVIGFSVYKMPKF 290
G W RGV+AGGC + ++ N Q+ + + T+ ISL Q + E + ++Y
Sbjct: 491 GEW-RGVTAGGCHVFPSW-RNNIQISVHVLYKTTIRISLEQIA-EEGNLTHIALYVFTAN 547
Query: 291 LTETANQMFFKRIKSTINSQYTNS--RQVSQRCQLESGAYLIMPTTFEPREEAQFTLRI- 347
E +M I T S R++ Q + G Y+I T++P E ++ + I
Sbjct: 548 EIEDKQRMLDIVDDCVIGEGTTFSLKRKIEQTIDFDKGWYIIFGCTYQPAIERRYLMEIE 607
Query: 348 YSNKPLKMKVLDDPPQMTKAALVKAPPGSDSNG 380
Y + ++K+L++ K + + + +NG
Sbjct: 608 YPDGSAQVKILNESETDWKLYQINSEWNNKNNG 640
Score = 37.5 bits (83), Expect = 0.83
Identities = 38/173 (21%), Positives = 69/173 (39%), Gaps = 7/173 (4%)
Query: 186 KGVWMLFS-DFQRLFPRIEMVHLDTETSRAELSLSEKQKWQMKMHQ--GGWKRGVSAGGC 242
KG +++F +Q R ++ ++ A++ + + + K++Q W + G
Sbjct: 584 KGWYIIFGCTYQPAIERRYLMEIEYPDGSAQVKILNESETDWKLYQINSEWNNKNNGGRI 643
Query: 243 RNYVNFFHTNPQVQIMLNEPDTVIISLNQHSIMEPKVIGFSVYKMPKFLTETANQMFFKR 302
+ + NP+ I P ++ I L I E IGF+++K T A +
Sbjct: 644 KRNSYQWCDNPKFIISSTHPTSLFILLVALGIDEDTEIGFALFKTKDDETPLA-VLTPGN 702
Query: 303 IKSTINSQYTNSRQVSQRCQLESGAYLIMPTTFEPREEAQFTLRIYSNKPLKM 355
IK T S + SG Y+++P + F L IYS + M
Sbjct: 703 IKEESEENDTTSSALVDNV---SGTYILIPYIRGNQSRTSFKLMIYSMSDISM 752
>UniRef50_A0CK52 Cluster: Chromosome undetermined scaffold_2, whole
genome shotgun sequence; n=3; Oligohymenophorea|Rep:
Chromosome undetermined scaffold_2, whole genome shotgun
sequence - Paramecium tetraurelia
Length = 920
Score = 45.2 bits (102), Expect = 0.004
Identities = 41/162 (25%), Positives = 71/162 (43%), Gaps = 19/162 (11%)
Query: 212 SRAELSLSEKQKWQMKMHQGGWKRGVSAGGCRNYVNFFHT---------NPQVQIMLNEP 262
S E+ L++ + + ++H G W++ +S GGC Y + + NP+ + EP
Sbjct: 762 SNQEVELTKLDETKNQVHIGKWEQDISDGGCHLYEDPYEKDTSKRTWTMNPKYSLQFFEP 821
Query: 263 DTVIISL-----NQHSIMEPKVIGF-SVYKMPKFLTETANQMFFKRIKSTINSQYTNSRQ 316
+ I+L N S + V G VY + K + N++ ++I N N Q
Sbjct: 822 IHITITLCIAEKNWKSKTKNTVGGMIGVYLIEK----SENKITTQQIVRVPNFLPINEIQ 877
Query: 317 VSQRCQLESGAYLIMPTTFEPREEAQFTLRIYSNKPLKMKVL 358
Q Y IMPTT++ + QF L + +K ++ L
Sbjct: 878 EEFDLQPTKNGYYIMPTTYQSKIHGQFILAVQGDKEFTLQAL 919
Score = 37.9 bits (84), Expect = 0.63
Identities = 19/37 (51%), Positives = 26/37 (70%), Gaps = 2/37 (5%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITE--SIVMPELS 83
+LHG+YE + G + +GL DLTGGI E S+ P+LS
Sbjct: 257 KLHGNYETICDGHIGEGLVDLTGGIAEINSLRDPQLS 293
>UniRef50_UPI0000ECC95E Cluster: Calpain-13 (EC 3.4.22.-).; n=2;
Gallus gallus|Rep: Calpain-13 (EC 3.4.22.-). - Gallus
gallus
Length = 759
Score = 44.8 bits (101), Expect = 0.005
Identities = 79/324 (24%), Positives = 126/324 (38%), Gaps = 45/324 (13%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVM----PELSD----GSALRTLLDTSSVVTA 100
+L GSY+ L G + D L D TGG+ + P+L D S R L+ S+ +
Sbjct: 187 KLQGSYQNLHGGYISDALVDFTGGVQMQFSLKDPPPDLEDVLKAASKSRCLMGCST--SG 244
Query: 101 HYFPPVTIISVFFLSLPTGIRLVKIRLRRSVINIFQVDTTNEPVYLIRLRRPLGHGET-- 158
V + T VKIR + N+ ++IR+ P GHGE
Sbjct: 245 WMRNTVLRNGIVQGHAYTVTGAVKIRFK------------NQWEHIIRVWNPWGHGEWRG 292
Query: 159 PISHIVLDTALWKTI-PQYERDRLMTASKG-VWMLFSDFQRLFPRIEMVHLDTETSRAEL 216
P S + W + P+ + + + G WM + +F+ F + + + T T +
Sbjct: 293 PWSD---GSPEWDYVEPEIKEELYRKKNDGEFWMSYENFREQFSWLCVCNC-TPTF-LDF 347
Query: 217 SLSEKQKWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPD----TVIISLNQ- 271
W ++ H W ++ G NPQ + + D V+ISL Q
Sbjct: 348 GDQRHTGWSVERHINLWSPLLATGRSNWSSGAVSKNPQYFFKVTKHDPKSYNVVISLIQK 407
Query: 272 -----HSIMEPKVIGFSVYKMPKFLTETANQMFF--KRIKSTINSQYTNSRQVSQRCQLE 324
H + K IGF + + + + F K + ++ +R VS L
Sbjct: 408 NAEGVHDAQKLK-IGFFITTVSTVALNSLSVHSFAPKENSKVLKQDFSLARDVSSCFNLS 466
Query: 325 SGAYLIMPTTFEPREEAQFTLRIY 348
G Y + P T E R E +F LRI+
Sbjct: 467 PGTYAVTPATTEDR-EFEFVLRIF 489
Score = 39.1 bits (87), Expect = 0.27
Identities = 16/43 (37%), Positives = 25/43 (58%)
Query: 6 IFGSTVGDKWLVSCLGVLYLCKGLFYRVVPADQRMDTSYAGVF 48
I +GD W+++ LG L + K +V+P DQ + YAG+F
Sbjct: 97 IIQGEIGDCWMLAALGSLTMQKQFLEKVLPKDQGFQSDYAGIF 139
Score = 38.7 bits (86), Expect = 0.36
Identities = 20/67 (29%), Positives = 35/67 (52%)
Query: 424 TLKHLQLVFKTHAREKMGVLRVERLRDALKDVGFIVPERVISLLVFRYMRKDGMLRFGDF 483
++ + Q +F+ R G L V L+ A++ G V E+++ L+ RY + F DF
Sbjct: 662 SVTNFQDLFRREDRNCSGFLDVYELKSAIQTAGLPVNEQILHLMALRYGNVYKRMGFADF 721
Query: 484 VSAVMHL 490
VS ++ L
Sbjct: 722 VSCMLRL 728
>UniRef50_O75808 Cluster: Calpain-15; n=13; Euteleostomi|Rep:
Calpain-15 - Homo sapiens (Human)
Length = 1086
Score = 44.8 bits (101), Expect = 0.005
Identities = 54/179 (30%), Positives = 81/179 (45%), Gaps = 19/179 (10%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVMPELSDGSALRTLLDTSSVVTAHYFPPVTI 108
+LHGSY AL+ G ++GLA LTG ES+ + +LS + +DT ++ A
Sbjct: 631 KLHGSYFALQAGRAIEGLATLTGAPCESLAL-QLSSTNPREEPVDT-DLIWAKMLSSKEA 688
Query: 109 ISVFFLSLPTGIRLV------KIRLR-RSVINIFQVDTTNEPVYLIRLRRPLGHGETPIS 161
+ S G V + LR R +I V + L+RLR P G S
Sbjct: 689 GFLMGASCGGGNMKVDDSAYESLGLRPRHAYSILDVRDV-QGTRLLRLRNPWGRFSWNGS 747
Query: 162 HIVLDTALWKTIPQYERDRLMT--ASKGV-WMLFSDFQRLFPRIEM--VHLDTETSRAE 215
+ W P + R LM +S+GV WM + DF R F +++ VH D + +R +
Sbjct: 748 W----SDEWPHWPGHLRGELMPHGSSEGVFWMEYGDFVRYFDSVDICKVHSDWQEARVQ 802
>UniRef50_Q640X7 Cluster: MGC84330 protein; n=3; Tetrapoda|Rep:
MGC84330 protein - Xenopus laevis (African clawed frog)
Length = 332
Score = 43.6 bits (98), Expect = 0.013
Identities = 21/72 (29%), Positives = 39/72 (54%)
Query: 423 DTLKHLQLVFKTHAREKMGVLRVERLRDALKDVGFIVPERVISLLVFRYMRKDGMLRFGD 482
+ +K Q ++K E+ G + + L ALK GF + +++ LL RY + G + F
Sbjct: 233 NNIKKWQCIYKQFDTERSGYINCQALPGALKAAGFDLHDQLHVLLARRYADESGNINFDS 292
Query: 483 FVSAVMHLHRVF 494
F+SA++ L ++
Sbjct: 293 FISALVRLDAMY 304
>UniRef50_Q6MZZ7 Cluster: Calpain-13; n=20; Mammalia|Rep: Calpain-13
- Homo sapiens (Human)
Length = 669
Score = 43.6 bits (98), Expect = 0.013
Identities = 86/370 (23%), Positives = 144/370 (38%), Gaps = 28/370 (7%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVM--PELSDGSALRTLLDTSSVVTAHYFPPV 106
+L GSY L YG L D L DLTGG+ +I + + A++T S++T
Sbjct: 175 KLLGSYSDLHYGFLEDALVDLTGGVITNIHLHSSPVDLVKAVKTATKAGSLITCATPSGP 234
Query: 107 TIISVFFLSLPTGIRLVKIRLRRSVINIFQVDTTNEPVYLIRLRRPLGHGETPISHIVLD 166
T + ++ G LV + +V Q+ +I L P G GE D
Sbjct: 235 TDTA---QAMENG--LVSLH-AYTVTGAEQIQYRRGWEEIISLWNPWGWGEAEWRGRWSD 288
Query: 167 -TALWKTIPQYERDRLMTASKG--VWMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQK 223
+ W+ + +L + WM DFQ+ F I M + + +
Sbjct: 289 GSQEWEETCDPRKSQLHKKREDGEFWMSCQDFQQKF--IAMFICSEIPITLDHGNTLHEG 346
Query: 224 WQMKMHQGGWKRGVSAGGCRN--YVNFFHTNPQVQIMLNEPDTVIISLNQHSIMEPKV-I 280
W M + G +AGG RN NF P + TV ++ + + K +
Sbjct: 347 WSQIMFRKQVILGNTAGGPRNDAQFNFSVQEPMEGTNVVVCVTVAVTPSNLKAEDAKFPL 406
Query: 281 GFSVYKM-PKFLTETANQMFFKRIKSTINSQYTN-SRQVSQRCQLESGAYLIMPTTFEPR 338
F V + E +FF ++T+ S R + L G Y+++ T R
Sbjct: 407 DFQVILAGSQRFREKFPPVFFSSFRNTVQSSNNKFRRNFTMTYHLSPGNYVVVAQT--RR 464
Query: 339 EEAQFTLRIYSNKPLKMKVLDDPPQMTKAALVKAPPGSDSNGFFQYETLFLQLADAHRTI 398
+ A+F LRI+ +K+ D ++ ++ +G +++F + A I
Sbjct: 465 KSAEFLLRIF------LKMPDSDRHLSSHFNLRMKGSPSEHG--SQQSIFNRYAQQRLDI 516
Query: 399 DIFELQELLD 408
D +LQ LL+
Sbjct: 517 DATQLQGLLN 526
>UniRef50_Q4RRV7 Cluster: Chromosome 7 SCAF15001, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 7
SCAF15001, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 584
Score = 43.2 bits (97), Expect = 0.017
Identities = 59/235 (25%), Positives = 100/235 (42%), Gaps = 30/235 (12%)
Query: 130 SVINIFQVDTTNEPVYLIRLRRPLGHGETPISHIVLDTALWKTIPQYERDRLMTASKG-V 188
+V + +V+ V L+RL P G E ++ W + ++ + G
Sbjct: 259 AVTGVTEVNCFGCDVKLVRLMNPWGRQEWN-GKWSDGSSEWDKLSAEDQKKCNKKEDGEF 317
Query: 189 WMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQKWQMKMHQGGWKRGVSAGG-CRNYVN 247
WM DF + +M+ + E + + W+ + ++G W G +AGG +Y
Sbjct: 318 WMELEDFCYYY---QMLFICCENP-SFIDRDVDCGWKYQTYEGSWVAGKTAGGDLSDYT- 372
Query: 248 FFHTNPQVQIMLNEPD-------TVIISLNQHSIMEPK------VIGFSVYKMPKFLTET 294
FH NPQ +I + E + V+ SL Q + IG +++K P E+
Sbjct: 373 -FHQNPQYRIQVAEENEEEKGSRNVLFSLMQKPQRSRRNKSRFFPIGLNIFKTPDGQLES 431
Query: 295 ANQMFFKRIKSTINSQ-YTNSRQVSQRCQLESGAYLIMPTTFE---PREEAQFTL 345
+FFK ++ Q Y R++++ LE G Y+I PT E P EE+ L
Sbjct: 432 ---VFFKNNQTVKEGQMYYFERELTEFYNLEPGEYVI-PTDEEEEQPMEESAICL 482
>UniRef50_UPI0000D56690 Cluster: PREDICTED: similar to calpain 8;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
calpain 8 - Tribolium castaneum
Length = 433
Score = 42.7 bits (96), Expect = 0.022
Identities = 46/191 (24%), Positives = 85/191 (44%), Gaps = 21/191 (10%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITE--SIVMPELSDGSALRTLLDTSSVVTAHYFPPV 106
+ +GSY++++ G + + L DL GG++E PEL + ++ + S F
Sbjct: 210 KFYGSYKSIEGGRINEALEDLCGGLSEVYDTRNPELYE--IIQMSYNKGS------FMGC 261
Query: 107 TIISVFFLSLPTGIRLVKIRLRRSVINIFQVDTTNEPVYLIRLRRPLGHGET--PISHIV 164
+I S + LV + S+ ++ N ++LIR+R P G E P S
Sbjct: 262 SIPSQNDGNGKRSDGLV-VNHAYSITGLYTSQLKNVTIHLIRVRNPWGSVEWNGPWSD-- 318
Query: 165 LDTALWKTIPQYERDRLMTASKG--VWMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQ 222
++ W +P+ + +L + WM F+DF F IE+ HL+ + + +
Sbjct: 319 -NSVCWSLVPKETKQKLWVKREDGEFWMNFTDFTEKFIFIEICHLN---PTFQTNTFQTN 374
Query: 223 KWQMKMHQGGW 233
W++ M + W
Sbjct: 375 NWKVYMFEDSW 385
>UniRef50_Q4S4V6 Cluster: Chromosome 2 SCAF14738, whole genome shotgun
sequence; n=8; Euteleostomi|Rep: Chromosome 2 SCAF14738,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 1345
Score = 42.7 bits (96), Expect = 0.022
Identities = 50/179 (27%), Positives = 83/179 (46%), Gaps = 19/179 (10%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVMPELSDGSALRTLLDTSSVVTAHYFPPVTI 108
+LHGSY AL+ G ++GLA LTG +S+++ ++S + +DT ++ A
Sbjct: 887 KLHGSYFALQAGRAIEGLATLTGAPCDSLML-QVSSTNPREEPIDT-DLIWAKMLSSKEA 944
Query: 109 ISVFFLSLPTGIRLV------KIRLR-RSVINIFQVDTTNEPVYLIRLRRPLGHGETPIS 161
+ S G V + LR R ++ V + L+RLR P G S
Sbjct: 945 GFLMGASCGGGNMKVDDAVYESLGLRPRHAYSVLDVRDV-QGYRLLRLRNPWGRFSWNGS 1003
Query: 162 HIVLDTALWKTIPQYERDRLMT--ASKGV-WMLFSDFQRLFPRIEM--VHLDTETSRAE 215
+ W PQ+ R LM +S+GV WM ++DF + F +++ +H D + R +
Sbjct: 1004 W----SDEWADWPQHLRHELMAHGSSEGVFWMEYTDFIKYFDSVDICKIHSDWQEVRLQ 1058
>UniRef50_Q7QGN5 Cluster: ENSANGP00000018264; n=6;
Endopterygota|Rep: ENSANGP00000018264 - Anopheles
gambiae str. PEST
Length = 737
Score = 41.9 bits (94), Expect = 0.039
Identities = 32/121 (26%), Positives = 55/121 (45%), Gaps = 11/121 (9%)
Query: 231 GGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPDTVIISLNQHSIMEPKV--IGFSVYKMP 288
G WK G +AGGC+N+ + NP ++ + DT + + + PKV +G + +
Sbjct: 616 GEWK-GRTAGGCQNHPLTYKNNPLYRLHIGPADTSDLVIE---LRGPKVYQVGLEL-TVV 670
Query: 289 KFLTETANQMFFKRIKSTINSQYTNSRQVSQRCQLESGAYLIMPTTFEPREEAQFTLRIY 348
ET F + S + V + +G Y + P+TF P +E+ F L++
Sbjct: 671 SLADETVTAPFVSQKTGVYRSGFC----VLDLAGIPAGVYQVRPSTFLPDQESPFFLKVK 726
Query: 349 S 349
S
Sbjct: 727 S 727
>UniRef50_Q4SWZ8 Cluster: Chromosome undetermined SCAF13274, whole
genome shotgun sequence; n=4; Euteleostomi|Rep:
Chromosome undetermined SCAF13274, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 168
Score = 40.7 bits (91), Expect = 0.089
Identities = 20/58 (34%), Positives = 34/58 (58%), Gaps = 4/58 (6%)
Query: 11 VGDKWLVSCLGVLYLCKGLFYRVVPADQRMDTSYAGVFRLHGSYEALKYGSLLDGLAD 68
+GD WL++ + L L K + RVVP DQ + +YAG+F ++ ++G +D + D
Sbjct: 58 LGDCWLLAAIASLTLNKQVLSRVVPHDQSFEENYAGIFH----FQFWQFGEWVDVVVD 111
>UniRef50_A3BVQ3 Cluster: Putative uncharacterized protein; n=3;
Oryza sativa|Rep: Putative uncharacterized protein -
Oryza sativa subsp. japonica (Rice)
Length = 304
Score = 40.3 bits (90), Expect = 0.12
Identities = 21/65 (32%), Positives = 36/65 (55%), Gaps = 3/65 (4%)
Query: 427 HLQLVFKTHAREKMGVLRVERLRDALKDVGFIVPERVISLLVFRY---MRKDGMLRFGDF 483
++Q +F + R+ G + + LR+AL+ +G+ VP V+ LL+ Y + G L F +F
Sbjct: 203 NIQGIFDRYDRDGSGKIEKDELREALRSLGYAVPPSVLELLIANYNNGVSSRGALDFDNF 262
Query: 484 VSAVM 488
V M
Sbjct: 263 VECGM 267
>UniRef50_Q5DBK8 Cluster: SJCHGC07600 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC07600 protein - Schistosoma
japonicum (Blood fluke)
Length = 125
Score = 39.9 bits (89), Expect = 0.16
Identities = 23/77 (29%), Positives = 44/77 (57%), Gaps = 3/77 (3%)
Query: 424 TLKHLQLVFKTHAREKMGVLRVERLRDALKDVGFIVPERVISLLVFRYM-RKDGMLRFGD 482
+++ L FK + ++ G ++ +LRD L++ G+ V RV S L RY+ K G + + +
Sbjct: 27 SIRGWSLAFKKYD-DRRGCVKSAKLRDLLRNAGYTVSNRVYSALAHRYVDLKSGRINYEN 85
Query: 483 FVSAVMHLHRVF-VQVY 498
F+ + ++ + F V VY
Sbjct: 86 FLYCMANVKQAFEVVVY 102
>UniRef50_A2E7M7 Cluster: Putative uncharacterized protein; n=3;
Trichomonas vaginalis G3|Rep: Putative uncharacterized
protein - Trichomonas vaginalis G3
Length = 2043
Score = 39.5 bits (88), Expect = 0.21
Identities = 30/126 (23%), Positives = 53/126 (42%), Gaps = 2/126 (1%)
Query: 297 QMFFKRIKSTINSQYTNSRQVSQRCQLESGAYLIMPTTFEPREEAQFTLRIYSNKPLKMK 356
QMF + + + S+ S + Q +L S + +++ R F+ R ++K
Sbjct: 1213 QMFMQVLMKLLLSK--KSMEAMQALELFSDSSIVVSLVHFYRSVELFSFRRTEKVLPQLK 1270
Query: 357 VLDDPPQMTKAALVKAPPGSDSNGFFQYETLFLQLADAHRTIDIFELQELLDACLPNDYI 416
+ L P + FFQ L ++L A I +F ELLD C +D++
Sbjct: 1271 EKLSQATIEDDLLGSVPVDVIKDSFFQMNDLLIKLCSARSQIHVFRFLELLDGCPVSDFL 1330
Query: 417 KSCVSI 422
K V++
Sbjct: 1331 KPRVAL 1336
>UniRef50_UPI0000D55C5A Cluster: PREDICTED: similar to CG1391-PB,
isoform B; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG1391-PB, isoform B - Tribolium castaneum
Length = 1124
Score = 38.7 bits (86), Expect = 0.36
Identities = 21/51 (41%), Positives = 28/51 (54%)
Query: 47 VFRLHGSYEALKYGSLLDGLADLTGGITESIVMPELSDGSALRTLLDTSSV 97
V ++HG YEAL G ++GLA LTG ESI + S + LDT +
Sbjct: 685 VAKIHGCYEALVSGRAIEGLATLTGAPCESIPLQASSIPAPAEEELDTDLI 735
>UniRef50_Q1RL55 Cluster: Zinc finger protein; n=6; Chordata|Rep:
Zinc finger protein - Ciona intestinalis (Transparent
sea squirt)
Length = 672
Score = 38.3 bits (85), Expect = 0.48
Identities = 39/163 (23%), Positives = 65/163 (39%), Gaps = 8/163 (4%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVMPELSDGSALR---TLLDTSSVVTAHYFPP 105
+LHG YEAL+ G ++GLA LTG ES+ + + + + + S + A Y
Sbjct: 220 KLHGCYEALQAGRSIEGLATLTGYPCESLALQQSCPETEVEEDMVWVKLLSSMEAGYLMG 279
Query: 106 VTIISVFFLSLPTGIRLVKIRLRR--SVINIFQVDTTNEPVYLIRLRRPLGHGETPISHI 163
+ + + +R R SV+ + L++LR P GH
Sbjct: 280 ASCGGGNMDTNDEEYNQIGLRPRHAYSVLRVTSEYNIKFIFRLVQLRNPWGHFSWK-GDW 338
Query: 164 VLDTALWKTIPQYERDRLM-TASKGV-WMLFSDFQRLFPRIEM 204
++ LW+ PQ A G WM D + F +++
Sbjct: 339 SNESVLWQQNPQLANQLFQRNADNGTFWMCLEDMMKYFDSVDI 381
>UniRef50_UPI0001555C79 Cluster: PREDICTED: similar to calpain 1,
partial; n=1; Ornithorhynchus anatinus|Rep: PREDICTED:
similar to calpain 1, partial - Ornithorhynchus anatinus
Length = 550
Score = 37.9 bits (84), Expect = 0.63
Identities = 16/41 (39%), Positives = 22/41 (53%)
Query: 8 GSTVGDKWLVSCLGVLYLCKGLFYRVVPADQRMDTSYAGVF 48
G GD WL++ + L L + +RVVP Q YAG+F
Sbjct: 252 GPAAGDCWLLAAIASLTLNDAILHRVVPHGQSFQNGYAGIF 292
>UniRef50_UPI0000D6828A Cluster: PREDICTED: hypothetical protein;
n=1; Mus musculus|Rep: PREDICTED: hypothetical protein -
Mus musculus
Length = 217
Score = 37.5 bits (83), Expect = 0.83
Identities = 18/53 (33%), Positives = 30/53 (56%)
Query: 438 EKMGVLRVERLRDALKDVGFIVPERVISLLVFRYMRKDGMLRFGDFVSAVMHL 490
+K G + LR ALK GF + ++ L+V RY +D L F D+++ ++ L
Sbjct: 133 DKSGTMSSYELRTALKAAGFQLGGHLLQLIVLRYADEDLQLDFDDYLNCLVRL 185
>UniRef50_Q0DH47 Cluster: Os05g0491900 protein; n=2; Oryza
sativa|Rep: Os05g0491900 protein - Oryza sativa subsp.
japonica (Rice)
Length = 547
Score = 37.5 bits (83), Expect = 0.83
Identities = 21/79 (26%), Positives = 42/79 (53%), Gaps = 1/79 (1%)
Query: 416 IKSCVSIDTLKHLQLVFKTHAREKMGVLRVERLRDALKDVGFIVPE-RVISLLVFRYMRK 474
I C+S + ++ L+ +FK+ + G + V+ LR L G + E V L+
Sbjct: 387 IAGCLSEEEIRGLKEMFKSMDSDNSGTITVDELRKGLAKKGTKLTEAEVQQLMEAADADG 446
Query: 475 DGMLRFGDFVSAVMHLHRV 493
+G + + +F++A MH++R+
Sbjct: 447 NGTIDYEEFITATMHMNRM 465
>UniRef50_Q4DSV7 Cluster: Calpain-like cysteine peptidase, putative;
n=3; Trypanosoma|Rep: Calpain-like cysteine peptidase,
putative - Trypanosoma cruzi
Length = 1067
Score = 37.5 bits (83), Expect = 0.83
Identities = 18/53 (33%), Positives = 29/53 (54%), Gaps = 1/53 (1%)
Query: 218 LSEKQKWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPDTVIISLN 270
+ + Q + QG W++GVS GG R + F NPQ + L++P + + LN
Sbjct: 755 IPQSQLKHCTVRQGKWEKGVSCGG-RTSLQTFAYNPQYLLTLSKPSMLSVRLN 806
>UniRef50_Q6DCQ4 Cluster: Capn3-prov protein; n=2; Xenopus|Rep:
Capn3-prov protein - Xenopus laevis (African clawed
frog)
Length = 704
Score = 37.1 bits (82), Expect = 1.1
Identities = 14/43 (32%), Positives = 26/43 (60%)
Query: 6 IFGSTVGDKWLVSCLGVLYLCKGLFYRVVPADQRMDTSYAGVF 48
I + +GD W++S +G + + L +++PADQ +Y G+F
Sbjct: 88 ILQNKIGDCWVLSTIGSVTQKQNLLIKIIPADQGFTKNYIGIF 130
>UniRef50_O29691 Cluster: Uncharacterized protein AF_0562; n=1;
Archaeoglobus fulgidus|Rep: Uncharacterized protein
AF_0562 - Archaeoglobus fulgidus
Length = 126
Score = 37.1 bits (82), Expect = 1.1
Identities = 16/44 (36%), Positives = 25/44 (56%)
Query: 347 IYSNKPLKMKVLDDPPQMTKAALVKAPPGSDSNGFFQYETLFLQ 390
+Y++KPL K+L+ PP + L+ PP S +Y LFL+
Sbjct: 69 LYAHKPLPFKLLNHPPHRRNSYLLPCPPLQPSTFLSEYSPLFLK 112
>UniRef50_Q7PZT3 Cluster: ENSANGP00000016570; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000016570 - Anopheles gambiae
str. PEST
Length = 200
Score = 36.3 bits (80), Expect = 1.9
Identities = 20/58 (34%), Positives = 29/58 (50%), Gaps = 4/58 (6%)
Query: 11 VGDKWLVSCLGVLYLCKGLFYRVVPADQRMDTSYAGVFRLHGSYEALKYGSLLDGLAD 68
+GD WL++ L +F RVVP D + YAGVF + +YG +D + D
Sbjct: 140 LGDCWLLAACANLTQDHKMFLRVVPEDNSFEDGYAGVFH----FRFWQYGKWVDVVID 193
>UniRef50_A1CRW2 Cluster: Calpain-like protease, putative; n=1;
Aspergillus clavatus|Rep: Calpain-like protease,
putative - Aspergillus clavatus
Length = 836
Score = 36.3 bits (80), Expect = 1.9
Identities = 31/129 (24%), Positives = 55/129 (42%), Gaps = 8/129 (6%)
Query: 230 QGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPDTVIISLNQHSIMEPKVIGFSVYKMPK 289
QG W + G + + NPQ +ML++ + I L + S E + + K
Sbjct: 574 QGAWTPSTAGGNAESAR--YPLNPQFSLMLSKATDISILL-ESSDTELAIHAKLFHSNGK 630
Query: 290 FLTETANQMFFKRIKSTINSQYTNSRQVSQRCQLESGAYLIMPTTFEPREEAQFTLRIYS 349
++ N+ T + Y +++ LE G Y I+ +TF + +FTL + S
Sbjct: 631 RVSRVRNRDII-----TDSGDYRRGAALAETKHLEKGVYTIVCSTFASDQLGRFTLWVSS 685
Query: 350 NKPLKMKVL 358
P ++K L
Sbjct: 686 MVPCEVKPL 694
>UniRef50_P27398 Cluster: Calpain-D; n=8; Eumetazoa|Rep: Calpain-D -
Drosophila melanogaster (Fruit fly)
Length = 1594
Score = 36.3 bits (80), Expect = 1.9
Identities = 17/31 (54%), Positives = 21/31 (67%)
Query: 47 VFRLHGSYEALKYGSLLDGLADLTGGITESI 77
V ++HG YEAL G ++GLA LTG ESI
Sbjct: 1156 VAKIHGCYEALVSGRAIEGLATLTGAPCESI 1186
>UniRef50_UPI00015B504A Cluster: PREDICTED: similar to small optic
lobes protein; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to small optic lobes protein - Nasonia
vitripennis
Length = 2116
Score = 35.9 bits (79), Expect = 2.5
Identities = 16/31 (51%), Positives = 21/31 (67%)
Query: 47 VFRLHGSYEALKYGSLLDGLADLTGGITESI 77
V ++HG YEAL G ++GLA LTG ES+
Sbjct: 1676 VAKIHGCYEALVSGRAIEGLATLTGAPCESV 1706
>UniRef50_UPI000051A8C7 Cluster: PREDICTED: similar to small optic
lobes CG1391-PB, isoform B; n=1; Apis mellifera|Rep:
PREDICTED: similar to small optic lobes CG1391-PB,
isoform B - Apis mellifera
Length = 1343
Score = 35.9 bits (79), Expect = 2.5
Identities = 16/31 (51%), Positives = 21/31 (67%)
Query: 47 VFRLHGSYEALKYGSLLDGLADLTGGITESI 77
V ++HG YEAL G ++GLA LTG ES+
Sbjct: 903 VAKIHGCYEALVSGRAIEGLATLTGAPCESV 933
>UniRef50_UPI000049A315 Cluster: calpain-like cysteine protease;
n=1; Entamoeba histolytica HM-1:IMSS|Rep: calpain-like
cysteine protease - Entamoeba histolytica HM-1:IMSS
Length = 591
Score = 35.9 bits (79), Expect = 2.5
Identities = 29/133 (21%), Positives = 58/133 (43%), Gaps = 6/133 (4%)
Query: 216 LSLSEKQKWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPDTVIISLNQHSIM 275
+ + ++W+ W + + G R F+ N Q I + + I++ Q
Sbjct: 307 IPIDYNKEWKFFEDSKKWTQTSNGGADRGSPYEFYHNYQYVIETKKDTKMSITMEQPD-- 364
Query: 276 EPKVIGFSVYKMPKFLTETANQMFFKRIKSTINSQYTNSRQVSQRCQLESGAYLIMPTTF 335
IGF +++ + T+ F + ++ T N ++ V + +L G Y+++P T
Sbjct: 365 NKNKIGFYLFETKQ--TDRKEIDFGELVEETTN--LISNVCVGKNFKLREGKYILVPCTS 420
Query: 336 EPREEAQFTLRIY 348
E E +F L+IY
Sbjct: 421 EAGEVGEFKLKIY 433
Score = 34.3 bits (75), Expect = 7.8
Identities = 29/117 (24%), Positives = 52/117 (44%), Gaps = 5/117 (4%)
Query: 220 EKQKWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPDTVIISLNQHSIMEPKV 279
E++K + +G WK+G AG + ++ NPQ + L + + L Q +I +V
Sbjct: 161 EEKKLDGIVLEGEWKKGFDAGNIISNPKWYE-NPQFLLTLTGKLHIKVCLKQDNINN-RV 218
Query: 280 IGFSVYKMPKFLTETANQMFFKRIKSTINSQYTN---SRQVSQRCQLESGAYLIMPT 333
F V F +F I+ + N S + +L++G+Y+I+PT
Sbjct: 219 TFFIVKYDQVFYENRPLTLFDPNEVIKIDENFLNTMASDNIEHSFELDAGSYVIIPT 275
>UniRef50_Q9FYE4 Cluster: EF-hand Calcium binding protein-like;
n=16; Magnoliophyta|Rep: EF-hand Calcium binding
protein-like - Arabidopsis thaliana (Mouse-ear cress)
Length = 354
Score = 35.9 bits (79), Expect = 2.5
Identities = 18/56 (32%), Positives = 33/56 (58%)
Query: 424 TLKHLQLVFKTHAREKMGVLRVERLRDALKDVGFIVPERVISLLVFRYMRKDGMLR 479
+L++ + +F+ +++ G + V LRDAL +GF V V+ LLV ++ + G R
Sbjct: 250 SLQNWRSIFERSDKDRSGRIDVNELRDALLSLGFSVSPVVLDLLVSKFDKSGGKNR 305
>UniRef50_Q96294 Cluster: Calcium-dependent protein kinase; n=5;
Magnoliophyta|Rep: Calcium-dependent protein kinase -
Arabidopsis thaliana (Mouse-ear cress)
Length = 503
Score = 35.9 bits (79), Expect = 2.5
Identities = 18/78 (23%), Positives = 41/78 (52%), Gaps = 1/78 (1%)
Query: 416 IKSCVSIDTLKHLQLVFKTHAREKMGVLRVERLRDALKDVGFIVPERVISLLVFRYMRKD 475
I +S + ++ ++++F + G++ +E L+ L+D + E + +L+ K
Sbjct: 348 IAEFLSTEEVEDIKVMFNKMDTDNDGIVSIEELKAGLRDFSTQLAESEVQMLIEAVDTKG 407
Query: 476 -GMLRFGDFVSAVMHLHR 492
G L +G+FV+ +HL +
Sbjct: 408 KGTLDYGEFVAVSLHLQK 425
>UniRef50_Q4RV78 Cluster: Chromosome 15 SCAF14992, whole genome
shotgun sequence; n=3; Clupeocephala|Rep: Chromosome 15
SCAF14992, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 496
Score = 35.5 bits (78), Expect = 3.4
Identities = 27/106 (25%), Positives = 46/106 (43%), Gaps = 11/106 (10%)
Query: 189 WMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQKWQMKMHQGGWKRGVSAGGCRNYVNF 248
W+ ++F+ F I + + + + ++ Q W QG W G +AGG RN+ +
Sbjct: 314 WLDETEFRSQFEDITVGYPSSVEGHLKSIYTDGQ-WDSTYFQGSWAEGRTAGGSRNFRSH 372
Query: 249 FHTNPQVQIMLNEPDT----VIISLNQHSIMEPKV----IGFSVYK 286
F NP + + ++ +N H P+ IGF VYK
Sbjct: 373 FQ-NPHFPFTVCDDSATSSGTVVRINLHQ-KRPETDLHPIGFHVYK 416
>UniRef50_A7NZQ0 Cluster: Chromosome chr6 scaffold_3, whole genome
shotgun sequence; n=5; Magnoliophyta|Rep: Chromosome
chr6 scaffold_3, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 520
Score = 35.5 bits (78), Expect = 3.4
Identities = 17/75 (22%), Positives = 41/75 (54%), Gaps = 1/75 (1%)
Query: 420 VSIDTLKHLQLVFKTHAREKMGVLRVERLRDALKDVGFIVPERVISLLV-FRYMRKDGML 478
+S++ + ++ FKT G + ++ LR L+ +G +P+ + +L+ + DG L
Sbjct: 347 LSMEEVAGIKEAFKTMDINNRGQINLDELRSGLQKLGQPIPDSDLQILMEAADLDGDGTL 406
Query: 479 RFGDFVSAVMHLHRV 493
+ +FV+ +H+ ++
Sbjct: 407 NYAEFVAVSIHIKKI 421
>UniRef50_A3C8D9 Cluster: Putative uncharacterized protein; n=3;
Oryza sativa|Rep: Putative uncharacterized protein -
Oryza sativa subsp. japonica (Rice)
Length = 487
Score = 35.5 bits (78), Expect = 3.4
Identities = 19/79 (24%), Positives = 43/79 (54%), Gaps = 1/79 (1%)
Query: 416 IKSCVSIDTLKHLQLVFKTHAREKMGVLRVERLRDALKDVGFIVPERVI-SLLVFRYMRK 474
I C+S + +K L+ +FK ++ G + +E L++ L G + I L+
Sbjct: 343 IAGCLSEEEIKGLKEMFKNIDKDNSGTITLEELKNGLAKQGTKFSDNEIEQLMEAADADG 402
Query: 475 DGMLRFGDFVSAVMHLHRV 493
+G++ + +FV+A +H++++
Sbjct: 403 NGIIDYEEFVTATVHMNKM 421
>UniRef50_A6S7E5 Cluster: Putative uncharacterized protein; n=2;
Sclerotiniaceae|Rep: Putative uncharacterized protein -
Botryotinia fuckeliana B05.10
Length = 1034
Score = 35.5 bits (78), Expect = 3.4
Identities = 14/36 (38%), Positives = 22/36 (61%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVMPELSD 84
+ HG Y A++ G +GL DLTGG+T + ++ D
Sbjct: 279 KAHGDYAAIEGGHTGEGLEDLTGGVTTEVFSTDILD 314
>UniRef50_Q17A99 Cluster: Adaptin, alpha/gamma/epsilon; n=2;
Culicidae|Rep: Adaptin, alpha/gamma/epsilon - Aedes
aegypti (Yellowfever mosquito)
Length = 872
Score = 35.1 bits (77), Expect = 4.4
Identities = 24/79 (30%), Positives = 41/79 (51%), Gaps = 3/79 (3%)
Query: 91 LLDTSSVVTAHYFPPVTIISVFFLSLPTGIRLVKIRLRRSVINIFQVDTTNEP---VYLI 147
L+ T ++VT +++ F S+PT +R +K + V+ ++P V ++
Sbjct: 252 LISTITLVTEMCEQSPVVLNYFKSSIPTLVRTLKTLIVSGYSPEHVVNGVSDPFLQVKIL 311
Query: 148 RLRRPLGHGETPISHIVLD 166
RL R LGHG+T S I+ D
Sbjct: 312 RLLRILGHGDTAQSEIMND 330
>UniRef50_Q0U7G1 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 1095
Score = 35.1 bits (77), Expect = 4.4
Identities = 13/36 (36%), Positives = 22/36 (61%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVMPELSD 84
+ HG Y A+ G + +G+ DLTGG+T + ++ D
Sbjct: 311 KAHGDYSAIDGGFVGEGIEDLTGGVTSEVFATDILD 346
>UniRef50_Q012Z6 Cluster: CG1391-PB, isoform B; n=2;
Ostreococcus|Rep: CG1391-PB, isoform B - Ostreococcus
tauri
Length = 841
Score = 34.7 bits (76), Expect = 5.9
Identities = 15/29 (51%), Positives = 19/29 (65%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESI 77
+ HGSY A+ G + +GL DLTG TE I
Sbjct: 349 KAHGSYSAISGGYVSEGLHDLTGSATEQI 377
>UniRef50_O65644 Cluster: Calcium-dependent serine/threonine protein
kinase; n=33; Magnoliophyta|Rep: Calcium-dependent
serine/threonine protein kinase - Arabidopsis thaliana
(Mouse-ear cress)
Length = 536
Score = 34.7 bits (76), Expect = 5.9
Identities = 23/76 (30%), Positives = 42/76 (55%), Gaps = 2/76 (2%)
Query: 420 VSIDTLKHLQLVFKTHAREKMGVLRVERLRDAL-KDVGFIVPE-RVISLLVFRYMRKDGM 477
++ D L L+ F +K G + +E +R AL KDV + + + RV +L DG+
Sbjct: 368 INEDELDDLRDQFDAIDIDKNGSISLEEMRQALAKDVPWKLKDARVAEILQANDSNTDGL 427
Query: 478 LRFGDFVSAVMHLHRV 493
+ F +FV A +H++++
Sbjct: 428 VDFTEFVVAALHVNQL 443
>UniRef50_UPI0000E480BA Cluster: PREDICTED: similar to toll-like
receptor Tlr1.1; n=4; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to toll-like receptor Tlr1.1 -
Strongylocentrotus purpuratus
Length = 688
Score = 34.3 bits (75), Expect = 7.8
Identities = 22/70 (31%), Positives = 35/70 (50%), Gaps = 1/70 (1%)
Query: 16 LVSCLGVLYLCKGLFYRVVPADQRMDTSYAGVFRLHGSYEALKYGSLLDGLADLTGGITE 75
L++ Y G+ +R P+ QR+D S + + R H + +L SL DGL +L + E
Sbjct: 241 LIASASADYFKSGITFRGTPSLQRLDLSDSNI-RSHHLWNSLTSTSLFDGLDNLAHLLLE 299
Query: 76 SIVMPELSDG 85
+ EL G
Sbjct: 300 GNRISELLQG 309
>UniRef50_Q6AQY3 Cluster: Related to outer membrane (Agglutination)
protein; n=1; Desulfotalea psychrophila|Rep: Related to
outer membrane (Agglutination) protein - Desulfotalea
psychrophila
Length = 554
Score = 34.3 bits (75), Expect = 7.8
Identities = 23/88 (26%), Positives = 38/88 (43%), Gaps = 3/88 (3%)
Query: 248 FFHTNPQVQIMLNEPDTVIISLNQHSIMEPKVIGFSVYKMPKFLTETANQMFFKRIKSTI 307
F P QI P+T+ I+ N H + KV +++ + ++ E AN F + +
Sbjct: 253 FITPEPTYQIPATLPETIEIAFNTHPAL--KVAKYNI-QTKRYAYEKANAADFPTLDFEV 309
Query: 308 NSQYTNSRQVSQRCQLESGAYLIMPTTF 335
QY + + + GAYL TF
Sbjct: 310 KGQYRDEIDGKEGDTTQVGAYLTFNYTF 337
>UniRef50_Q8X0W5 Cluster: Related to micromolar calcium activated
neutral protease 1; n=2; Neurospora crassa|Rep: Related
to micromolar calcium activated neutral protease 1 -
Neurospora crassa
Length = 1266
Score = 34.3 bits (75), Expect = 7.8
Identities = 13/36 (36%), Positives = 22/36 (61%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVMPELSD 84
+ HG Y A++ G +G+ DLTGG+T + ++ D
Sbjct: 320 KAHGDYAAIEGGFTGEGIEDLTGGVTSGLYTADILD 355
>UniRef50_A2QVX3 Cluster: Contig An11c0110, complete genome; n=1;
Aspergillus niger|Rep: Contig An11c0110, complete genome
- Aspergillus niger
Length = 793
Score = 34.3 bits (75), Expect = 7.8
Identities = 13/36 (36%), Positives = 22/36 (61%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVMPELSD 84
+ HG Y A++ G + + L DLTGG+T ++ + D
Sbjct: 252 KAHGDYSAIEGGFVGEALEDLTGGVTSDVLTSNILD 287
>UniRef50_Q06850 Cluster: Calcium-dependent protein kinase isoform
AK1; n=37; Viridiplantae|Rep: Calcium-dependent protein
kinase isoform AK1 - Arabidopsis thaliana (Mouse-ear
cress)
Length = 610
Score = 34.3 bits (75), Expect = 7.8
Identities = 19/79 (24%), Positives = 41/79 (51%), Gaps = 1/79 (1%)
Query: 416 IKSCVSIDTLKHLQLVFKTHAREKMGVLRVERLRDALKDVGFIVPE-RVISLLVFRYMRK 474
I +S + + L+ +F +K G + E L+ LK VG + E ++ L+ +
Sbjct: 444 IAESLSEEEIAGLKEMFNMIDADKSGQITFEELKAGLKRVGANLKESEILDLMQAADVDN 503
Query: 475 DGMLRFGDFVSAVMHLHRV 493
G + + +F++A +HL+++
Sbjct: 504 SGTIDYKEFIAATLHLNKI 522
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.325 0.139 0.415
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 553,385,379
Number of Sequences: 1657284
Number of extensions: 22517658
Number of successful extensions: 64034
Number of sequences better than 10.0: 110
Number of HSP's better than 10.0 without gapping: 89
Number of HSP's successfully gapped in prelim test: 21
Number of HSP's that attempted gapping in prelim test: 63619
Number of HSP's gapped (non-prelim): 296
length of query: 510
length of database: 575,637,011
effective HSP length: 104
effective length of query: 406
effective length of database: 403,279,475
effective search space: 163731466850
effective search space used: 163731466850
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 40 (21.6 bits)
S2: 75 (34.3 bits)
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