Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA002120-TA|BGIBMGA002120-PA|IPR001300|Peptidase C2,
calpain, IPR000834|Peptidase M14, carboxypeptidase A
(510 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC027993-1|AAH27993.1| 627|Homo sapiens CAPN9 protein protein. 168 4e-41
AY874864-1|AAW49735.1| 690|Homo sapiens calpain 9 protein. 168 4e-41
AL591291-2|CAI17214.1| 690|Homo sapiens calpain 9 protein. 168 4e-41
AL512328-3|CAI14865.1| 690|Homo sapiens calpain 9 protein. 168 4e-41
AF022799-1|AAB80762.1| 690|Homo sapiens digestive tract-specifi... 168 4e-41
X04366-1|CAA27881.1| 714|Homo sapiens protein ( Human mRNA for ... 158 5e-38
BC017200-1|AAH17200.1| 714|Homo sapiens calpain 1, (mu/I) large... 158 5e-38
AY796340-1|AAV41878.1| 714|Homo sapiens calpain 1, (mu/I) large... 158 5e-38
AY550975-1|AAT52221.1| 714|Homo sapiens cell proliferation-indu... 158 5e-38
BC075862-1|AAH75862.1| 714|Homo sapiens CAPN1 protein protein. 157 7e-38
BC008751-1|AAH08751.1| 714|Homo sapiens calpain 1, (mu/I) large... 157 7e-38
BC021303-1|AAH21303.1| 700|Homo sapiens calpain 2, (m/II) large... 149 2e-35
AY835586-1|AAV80421.1| 700|Homo sapiens calpain 2, (m/II) large... 149 2e-35
AL591291-1|CAI17215.1| 664|Homo sapiens calpain 9 protein. 149 2e-35
AL512328-2|CAI14866.1| 664|Homo sapiens calpain 9 protein. 149 2e-35
AB038463-1|BAA92137.1| 664|Homo sapiens GC36 protein. 149 2e-35
AB209855-1|BAD93092.1| 729|Homo sapiens Calpain 2, large [catal... 148 5e-35
M23254-1|AAA35645.1| 700|Homo sapiens neutral protease large su... 147 7e-35
AF261089-1|AAF99682.1| 700|Homo sapiens calpain large polypepti... 147 9e-35
BC011828-1|AAH11828.1| 610|Homo sapiens Unknown (protein for IM... 146 1e-34
BC007686-1|AAH07686.1| 610|Homo sapiens Unknown (protein for IM... 146 1e-34
AF127765-1|AAD28254.3| 729|Homo sapiens calpain 3 protein. 144 5e-34
BC033733-1|AAH33733.1| 702|Homo sapiens calpain 11 protein. 136 2e-31
AL365192-3|CAI20532.2| 739|Homo sapiens calpain 11 protein. 136 2e-31
AJ242832-1|CAB52137.1| 702|Homo sapiens calpain protein. 136 2e-31
X85030-1|CAA59403.1| 821|Homo sapiens calpain protein. 111 6e-24
AY902237-1|AAW69391.1| 821|Homo sapiens calpain 3, (p94) protein. 111 6e-24
AF209502-1|AAL40183.1| 821|Homo sapiens calpain protein. 111 6e-24
AF127764-1|AAD28253.1| 815|Homo sapiens calpain 3 protein. 111 6e-24
AB117940-1|BAD16649.1| 728|Homo sapiens hUp84 protein. 111 6e-24
CR628412-1|CAM28354.1| 437|Homo sapiens calpain 8 (nCL-2) protein. 99 2e-20
Y10552-1|CAA71584.1| 634|Homo sapiens CAPN5 protein protein. 88 6e-17
BC018123-1|AAH18123.1| 640|Homo sapiens calpain 5 protein. 88 6e-17
AB209087-1|BAD92324.1| 678|Homo sapiens Hypothetical protein FL... 88 8e-17
U94346-1|AAC51869.1| 639|Homo sapiens calpain-like protease pro... 87 1e-16
AK128124-1|BAC87282.1| 680|Homo sapiens protein ( Homo sapiens ... 86 2e-16
CR628412-2|CAM28355.1| 381|Homo sapiens calpain 8 (nCL-2) protein. 86 3e-16
AK127398-1|BAC86959.1| 719|Homo sapiens protein ( Homo sapiens ... 73 2e-12
AB117941-1|BAD16650.1| 426|Homo sapiens hUp49 protein. 73 2e-12
BC000730-1|AAH00730.1| 641|Homo sapiens calpain 6 protein. 69 3e-11
AY800242-1|AAV41896.1| 641|Homo sapiens calpain 6 protein. 69 3e-11
AL031117-4|CAA19965.1| 641|Homo sapiens calpain 6 protein. 69 3e-11
AJ000388-1|CAA04051.1| 641|Homo sapiens calpain-like protease, ... 69 3e-11
AF029232-1|AAB86605.1| 641|Homo sapiens calpamodulin protein. 69 3e-11
AF089090-1|AAG17968.1| 544|Homo sapiens calpain-like protease C... 65 6e-10
AK074807-1|BAC11220.1| 672|Homo sapiens protein ( Homo sapiens ... 64 1e-09
BC007553-1|AAH07553.2| 672|Homo sapiens calpain 10 protein. 63 2e-09
BC004260-1|AAH04260.1| 672|Homo sapiens calpain 10 protein. 63 2e-09
AF089092-1|AAG17970.1| 513|Homo sapiens calpain-like protease C... 63 2e-09
AF089088-1|AAG17966.1| 672|Homo sapiens calpain-like protease C... 63 2e-09
AC124862-2|AAX88944.1| 672|Homo sapiens unknown protein. 63 2e-09
AB058748-1|BAB47474.1| 705|Homo sapiens KIAA1845 protein protein. 63 2e-09
AK124751-1|BAC85936.1| 210|Homo sapiens protein ( Homo sapiens ... 59 4e-08
AF089091-1|AAG17969.1| 517|Homo sapiens calpain-like protease C... 58 7e-08
AF089093-1|AAG17971.1| 444|Homo sapiens calpain-like protease C... 54 2e-06
BC006000-1|AAH06000.1| 248|Homo sapiens calpain, small subunit ... 51 1e-05
BC005397-1|AAH05397.1| 248|Homo sapiens calpain, small subunit ... 51 1e-05
AY052551-1|AAL02241.1| 248|Homo sapiens calpain small subunit 2... 51 1e-05
BT007322-1|AAP35986.1| 309|Homo sapiens calpain 3, (p94) protein. 50 1e-05
BC003169-1|AAH03169.1| 309|Homo sapiens calpain 3, (p94) protein. 50 1e-05
BC117347-1|AAI17348.1| 669|Homo sapiens calpain 13 protein. 46 4e-04
BC117345-1|AAI17346.1| 669|Homo sapiens calpain 13 protein. 46 4e-04
Z97986-1|CAC14067.1| 1086|Homo sapiens small optic lobes homolog... 45 7e-04
U85647-1|AAC33822.1| 1086|Homo sapiens small optic lobes homolog... 45 7e-04
BC021854-1|AAH21854.1| 562|Homo sapiens Similar to small optic ... 45 7e-04
AE006464-1|AAK61233.1| 1086|Homo sapiens small optic lobes homol... 45 7e-04
X04106-1|CAA27726.1| 268|Homo sapiens protein ( Human mRNA for ... 40 0.028
M31511-1|AAA35646.1| 268|Homo sapiens protein ( Human calcium-a... 40 0.028
BT009775-1|AAP88777.1| 268|Homo sapiens calpain, small subunit ... 40 0.028
BC064998-1|AAH64998.1| 268|Homo sapiens CAPNS1 protein protein. 40 0.028
BC023643-1|AAH23643.1| 268|Homo sapiens calpain, small subunit ... 40 0.028
BC021933-1|AAH21933.1| 268|Homo sapiens calpain, small subunit ... 40 0.028
BC018931-1|AAH18931.1| 268|Homo sapiens calpain, small subunit ... 40 0.028
BC017308-1|AAH17308.1| 268|Homo sapiens calpain, small subunit ... 40 0.028
BC011903-1|AAH11903.1| 322|Homo sapiens CAPNS1 protein protein. 40 0.028
BC007779-1|AAH07779.1| 268|Homo sapiens calpain, small subunit ... 40 0.028
BC000592-1|AAH00592.1| 268|Homo sapiens calpain, small subunit ... 40 0.028
AY789642-1|AAV40829.1| 268|Homo sapiens calpain, small subunit ... 40 0.028
AD001527-4|AAB51183.1| 268|Homo sapiens calcium-dependent prote... 40 0.028
AC002984-1|AAB81546.1| 268|Homo sapiens CANS_Human protein. 40 0.028
BC128605-1|AAI28606.1| 156|Homo sapiens calpain 3, (p94) protein. 39 0.048
BC107791-1|AAI07792.1| 156|Homo sapiens CAPN3 protein protein. 39 0.048
BC100783-1|AAI00784.1| 174|Homo sapiens CAPN3 protein protein. 39 0.048
BC100782-1|AAI00783.1| 156|Homo sapiens calpain 3, (p94) protein. 39 0.048
BC067126-1|AAH67126.1| 156|Homo sapiens calpain 3, (p94) protein. 39 0.048
BC007810-1|AAH07810.3| 156|Homo sapiens calpain 3, (p94) protein. 39 0.048
BC004883-1|AAH04883.1| 156|Homo sapiens calpain 3, (p94) protein. 39 0.048
BC003521-1|AAH03521.1| 156|Homo sapiens calpain 3, (p94) protein. 39 0.048
BC100784-1|AAI00785.1| 156|Homo sapiens calpain 3, (p94) protein. 38 0.064
AK074418-1|BAB85075.1| 423|Homo sapiens protein ( Homo sapiens ... 35 0.78
AC092569-1|AAX82015.1| 423|Homo sapiens unknown protein. 35 0.78
AF089096-1|AAG17974.1| 138|Homo sapiens calpain-like protease C... 33 1.8
CR848842-2|CAM45846.1| 156|Homo sapiens calpain 8 (nCL-2) protein. 33 3.2
AB058743-1|BAB47469.2| 2443|Homo sapiens KIAA1840 protein protein. 32 5.5
>BC027993-1|AAH27993.1| 627|Homo sapiens CAPN9 protein protein.
Length = 627
Score = 168 bits (409), Expect = 4e-41
Identities = 146/491 (29%), Positives = 230/491 (46%), Gaps = 60/491 (12%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVMPELSDG--SALRTLLDTSSVVTAHYFPPV 106
+L+GSYEALK GS ++ + D TGG+ E+ E + L L S++ +
Sbjct: 116 KLNGSYEALKGGSAIEAMEDFTGGVAETFQTKEAPENFYEILEKALKRGSLLGCF----I 171
Query: 107 TIISVFFLSLPTGIRLVKIRLRRSVINIFQVDTTNEPVYLIRLRRPLGHGETPISHIVLD 166
S T L+K SV I QV + + LIR+R P G E S
Sbjct: 172 DTRSAAESEARTPFGLIKGHAY-SVTGIDQVSFRGQRIELIRIRNPWGQVEWNGSWSD-S 229
Query: 167 TALWKTIPQYERDRLMTASKG---VWMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQK 223
+ W+++ E+ RL + WM F DF+ F ++E+ +L + L K
Sbjct: 230 SPEWRSVGPAEQKRLCHTALDDGEFWMAFQDFKAHFDKVEICNLTPDA----LEEDAIHK 285
Query: 224 WQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPD------TVIISLNQHSIMEP 277
W++ +HQG W RG +AGGCRN+++ F TNPQ+++ L E D + +++L Q +
Sbjct: 286 WEVTVHQGSWVRGSTAGGCRNFLDTFWTNPQIKLSLTEKDEGQEECSFLVALMQKDRRKL 345
Query: 278 K-------VIGFSVYKMPKFLTETANQMFFKRIKSTINSQ-YTNSRQVSQRCQLESGAYL 329
K IG+++Y+ P E N+ FF+ S S+ + N R+VS R +L G Y+
Sbjct: 346 KRFGANVLTIGYAIYECPD-KDEHLNKDFFRYHASRARSKTFINLREVSDRFKLPPGEYI 404
Query: 330 IMPTTFEPREEAQFTLRIYSNKPLKMKVLDDPPQMTKAALVK-APPGSDSNGFFQYETLF 388
++P+TFEP +EA F LRI+S K + +D + K PP ++ ++ LF
Sbjct: 405 LIPSTFEPHQEADFCLRIFSEKKAITRDMDGNVDIDLPEPPKPTPPDQETEEEQRFRALF 464
Query: 389 LQLADAHRTIDIFELQELLDACLPNDY-IK-------SCVSI----DT------------ 424
Q+A + EL+ +L+A L IK SC +I DT
Sbjct: 465 EQVAGEDMEVTAEELEYVLNAVLQKKKDIKFKKLSLISCKNIISLMDTSGNGKLEFDEFK 524
Query: 425 -----LKHLQLVFKTHAREKMGVLRVERLRDALKDVGFIVPERVISLLVFRYMRKDGMLR 479
LK +F +K G + LR ALK GF + ++ L+V RY ++ L
Sbjct: 525 VFWDKLKQWINLFLRFDADKSGTMSTYELRTALKAAGFQLSSHLLQLIVLRYADEELQLD 584
Query: 480 FGDFVSAVMHL 490
F DF++ ++ L
Sbjct: 585 FDDFLNCLVRL 595
>AY874864-1|AAW49735.1| 690|Homo sapiens calpain 9 protein.
Length = 690
Score = 168 bits (409), Expect = 4e-41
Identities = 146/491 (29%), Positives = 230/491 (46%), Gaps = 60/491 (12%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVMPELSDG--SALRTLLDTSSVVTAHYFPPV 106
+L+GSYEALK GS ++ + D TGG+ E+ E + L L S++ +
Sbjct: 179 KLNGSYEALKGGSAIEAMEDFTGGVAETFQTKEAPENFYEILEKALKRGSLLGCF----I 234
Query: 107 TIISVFFLSLPTGIRLVKIRLRRSVINIFQVDTTNEPVYLIRLRRPLGHGETPISHIVLD 166
S T L+K SV I QV + + LIR+R P G E S
Sbjct: 235 DTRSAAESEARTPFGLIKGHAY-SVTGIDQVSFRGQRIELIRIRNPWGQVEWNGSWSD-S 292
Query: 167 TALWKTIPQYERDRLMTASKG---VWMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQK 223
+ W+++ E+ RL + WM F DF+ F ++E+ +L + L K
Sbjct: 293 SPEWRSVGPAEQKRLCHTALDDGEFWMAFKDFKAHFDKVEICNLTPDA----LEEDAIHK 348
Query: 224 WQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPD------TVIISLNQHSIMEP 277
W++ +HQG W RG +AGGCRN+++ F TNPQ+++ L E D + +++L Q +
Sbjct: 349 WEVTVHQGSWVRGSTAGGCRNFLDTFWTNPQIKLSLTEKDEGQEECSFLVALMQKDRRKL 408
Query: 278 K-------VIGFSVYKMPKFLTETANQMFFKRIKSTINSQ-YTNSRQVSQRCQLESGAYL 329
K IG+++Y+ P E N+ FF+ S S+ + N R+VS R +L G Y+
Sbjct: 409 KRFGANVLTIGYAIYECPD-KDEHLNKDFFRYHASRARSKTFINLREVSDRFKLPPGEYI 467
Query: 330 IMPTTFEPREEAQFTLRIYSNKPLKMKVLDDPPQMTKAALVK-APPGSDSNGFFQYETLF 388
++P+TFEP +EA F LRI+S K + +D + K PP ++ ++ LF
Sbjct: 468 LIPSTFEPHQEADFCLRIFSEKKAITRDMDGNVDIDLPEPPKPTPPDQETEEEQRFRALF 527
Query: 389 LQLADAHRTIDIFELQELLDACLPNDY-IK-------SCVSI----DT------------ 424
Q+A + EL+ +L+A L IK SC +I DT
Sbjct: 528 EQVAGEDMEVTAEELEYVLNAVLQKKKDIKFKKLSLISCKNIISLMDTSGNGKLEFDEFK 587
Query: 425 -----LKHLQLVFKTHAREKMGVLRVERLRDALKDVGFIVPERVISLLVFRYMRKDGMLR 479
LK +F +K G + LR ALK GF + ++ L+V RY ++ L
Sbjct: 588 VFWDKLKQWINLFLRFDADKSGTMSTYELRTALKAAGFQLSSHLLQLIVLRYADEELQLD 647
Query: 480 FGDFVSAVMHL 490
F DF++ ++ L
Sbjct: 648 FDDFLNCLVRL 658
Score = 35.5 bits (78), Expect = 0.45
Identities = 15/38 (39%), Positives = 22/38 (57%)
Query: 11 VGDKWLVSCLGVLYLCKGLFYRVVPADQRMDTSYAGVF 48
+GD WL++ + L L + RV+P DQ YAG+F
Sbjct: 94 LGDCWLLAAIASLTLNQKALARVIPQDQSFGPGYAGIF 131
>AL591291-2|CAI17214.1| 690|Homo sapiens calpain 9 protein.
Length = 690
Score = 168 bits (409), Expect = 4e-41
Identities = 146/491 (29%), Positives = 230/491 (46%), Gaps = 60/491 (12%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVMPELSDG--SALRTLLDTSSVVTAHYFPPV 106
+L+GSYEALK GS ++ + D TGG+ E+ E + L L S++ +
Sbjct: 179 KLNGSYEALKGGSAIEAMEDFTGGVAETFQTKEAPENFYEILEKALKRGSLLGCF----I 234
Query: 107 TIISVFFLSLPTGIRLVKIRLRRSVINIFQVDTTNEPVYLIRLRRPLGHGETPISHIVLD 166
S T L+K SV I QV + + LIR+R P G E S
Sbjct: 235 DTRSAAESEARTPFGLIKGHAY-SVTGIDQVSFRGQRIELIRIRNPWGQVEWNGSWSD-S 292
Query: 167 TALWKTIPQYERDRLMTASKG---VWMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQK 223
+ W+++ E+ RL + WM F DF+ F ++E+ +L + L K
Sbjct: 293 SPEWRSVGPAEQKRLCHTALDDGEFWMAFKDFKAHFDKVEICNLTPDA----LEEDAIHK 348
Query: 224 WQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPD------TVIISLNQHSIMEP 277
W++ +HQG W RG +AGGCRN+++ F TNPQ+++ L E D + +++L Q +
Sbjct: 349 WEVTVHQGSWVRGSTAGGCRNFLDTFWTNPQIKLSLTEKDEGQEECSFLVALMQKDRRKL 408
Query: 278 K-------VIGFSVYKMPKFLTETANQMFFKRIKSTINSQ-YTNSRQVSQRCQLESGAYL 329
K IG+++Y+ P E N+ FF+ S S+ + N R+VS R +L G Y+
Sbjct: 409 KRFGANVLTIGYAIYECPD-KDEHLNKDFFRYHASRARSKTFINLREVSDRFKLPPGEYI 467
Query: 330 IMPTTFEPREEAQFTLRIYSNKPLKMKVLDDPPQMTKAALVK-APPGSDSNGFFQYETLF 388
++P+TFEP +EA F LRI+S K + +D + K PP ++ ++ LF
Sbjct: 468 LIPSTFEPHQEADFCLRIFSEKKAITRDMDGNVDIDLPEPPKPTPPDQETEEEQRFRALF 527
Query: 389 LQLADAHRTIDIFELQELLDACLPNDY-IK-------SCVSI----DT------------ 424
Q+A + EL+ +L+A L IK SC +I DT
Sbjct: 528 EQVAGEDMEVTAEELEYVLNAVLQKKKDIKFKKLSLISCKNIISLMDTSGNGKLEFDEFK 587
Query: 425 -----LKHLQLVFKTHAREKMGVLRVERLRDALKDVGFIVPERVISLLVFRYMRKDGMLR 479
LK +F +K G + LR ALK GF + ++ L+V RY ++ L
Sbjct: 588 VFWDKLKQWINLFLRFDADKSGTMSTYELRTALKAAGFQLSSHLLQLIVLRYADEELQLD 647
Query: 480 FGDFVSAVMHL 490
F DF++ ++ L
Sbjct: 648 FDDFLNCLVRL 658
Score = 35.5 bits (78), Expect = 0.45
Identities = 15/38 (39%), Positives = 22/38 (57%)
Query: 11 VGDKWLVSCLGVLYLCKGLFYRVVPADQRMDTSYAGVF 48
+GD WL++ + L L + RV+P DQ YAG+F
Sbjct: 94 LGDCWLLAAIASLTLNQKALARVIPQDQSFGPGYAGIF 131
>AL512328-3|CAI14865.1| 690|Homo sapiens calpain 9 protein.
Length = 690
Score = 168 bits (409), Expect = 4e-41
Identities = 146/491 (29%), Positives = 230/491 (46%), Gaps = 60/491 (12%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVMPELSDG--SALRTLLDTSSVVTAHYFPPV 106
+L+GSYEALK GS ++ + D TGG+ E+ E + L L S++ +
Sbjct: 179 KLNGSYEALKGGSAIEAMEDFTGGVAETFQTKEAPENFYEILEKALKRGSLLGCF----I 234
Query: 107 TIISVFFLSLPTGIRLVKIRLRRSVINIFQVDTTNEPVYLIRLRRPLGHGETPISHIVLD 166
S T L+K SV I QV + + LIR+R P G E S
Sbjct: 235 DTRSAAESEARTPFGLIKGHAY-SVTGIDQVSFRGQRIELIRIRNPWGQVEWNGSWSD-S 292
Query: 167 TALWKTIPQYERDRLMTASKG---VWMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQK 223
+ W+++ E+ RL + WM F DF+ F ++E+ +L + L K
Sbjct: 293 SPEWRSVGPAEQKRLCHTALDDGEFWMAFKDFKAHFDKVEICNLTPDA----LEEDAIHK 348
Query: 224 WQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPD------TVIISLNQHSIMEP 277
W++ +HQG W RG +AGGCRN+++ F TNPQ+++ L E D + +++L Q +
Sbjct: 349 WEVTVHQGSWVRGSTAGGCRNFLDTFWTNPQIKLSLTEKDEGQEECSFLVALMQKDRRKL 408
Query: 278 K-------VIGFSVYKMPKFLTETANQMFFKRIKSTINSQ-YTNSRQVSQRCQLESGAYL 329
K IG+++Y+ P E N+ FF+ S S+ + N R+VS R +L G Y+
Sbjct: 409 KRFGANVLTIGYAIYECPD-KDEHLNKDFFRYHASRARSKTFINLREVSDRFKLPPGEYI 467
Query: 330 IMPTTFEPREEAQFTLRIYSNKPLKMKVLDDPPQMTKAALVK-APPGSDSNGFFQYETLF 388
++P+TFEP +EA F LRI+S K + +D + K PP ++ ++ LF
Sbjct: 468 LIPSTFEPHQEADFCLRIFSEKKAITRDMDGNVDIDLPEPPKPTPPDQETEEEQRFRALF 527
Query: 389 LQLADAHRTIDIFELQELLDACLPNDY-IK-------SCVSI----DT------------ 424
Q+A + EL+ +L+A L IK SC +I DT
Sbjct: 528 EQVAGEDMEVTAEELEYVLNAVLQKKKDIKFKKLSLISCKNIISLMDTSGNGKLEFDEFK 587
Query: 425 -----LKHLQLVFKTHAREKMGVLRVERLRDALKDVGFIVPERVISLLVFRYMRKDGMLR 479
LK +F +K G + LR ALK GF + ++ L+V RY ++ L
Sbjct: 588 VFWDKLKQWINLFLRFDADKSGTMSTYELRTALKAAGFQLSSHLLQLIVLRYADEELQLD 647
Query: 480 FGDFVSAVMHL 490
F DF++ ++ L
Sbjct: 648 FDDFLNCLVRL 658
Score = 35.5 bits (78), Expect = 0.45
Identities = 15/38 (39%), Positives = 22/38 (57%)
Query: 11 VGDKWLVSCLGVLYLCKGLFYRVVPADQRMDTSYAGVF 48
+GD WL++ + L L + RV+P DQ YAG+F
Sbjct: 94 LGDCWLLAAIASLTLNQKALARVIPQDQSFGPGYAGIF 131
>AF022799-1|AAB80762.1| 690|Homo sapiens digestive tract-specific
calpain protein.
Length = 690
Score = 168 bits (409), Expect = 4e-41
Identities = 146/491 (29%), Positives = 230/491 (46%), Gaps = 60/491 (12%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVMPELSDG--SALRTLLDTSSVVTAHYFPPV 106
+L+GSYEALK GS ++ + D TGG+ E+ E + L L S++ +
Sbjct: 179 KLNGSYEALKGGSAIEAMEDFTGGVAETFQTKEAPENFYEILEKALKRGSLLGCF----I 234
Query: 107 TIISVFFLSLPTGIRLVKIRLRRSVINIFQVDTTNEPVYLIRLRRPLGHGETPISHIVLD 166
S T L+K SV I QV + + LIR+R P G E S
Sbjct: 235 DTRSAAESEARTPFGLIKGHAY-SVTGIDQVSFRGQRIELIRIRNPWGQVEWNGSWSD-S 292
Query: 167 TALWKTIPQYERDRLMTASKG---VWMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQK 223
+ W+++ E+ RL + WM F DF+ F ++E+ +L + L K
Sbjct: 293 SPEWRSVGPAEQKRLCHTALDDGEFWMAFKDFKAHFDKVEICNLTPDA----LEEDAIHK 348
Query: 224 WQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPD------TVIISLNQHSIMEP 277
W++ +HQG W RG +AGGCRN+++ F TNPQ+++ L E D + +++L Q +
Sbjct: 349 WEVTVHQGSWVRGSTAGGCRNFLDTFWTNPQIKLSLTEKDEGQEECSFLVALMQKDRRKL 408
Query: 278 K-------VIGFSVYKMPKFLTETANQMFFKRIKSTINSQ-YTNSRQVSQRCQLESGAYL 329
K IG+++Y+ P E N+ FF+ S S+ + N R+VS R +L G Y+
Sbjct: 409 KRFGANVLTIGYAIYECPD-KDEHLNKDFFRYHASRARSKTFINLREVSDRFKLPPGEYI 467
Query: 330 IMPTTFEPREEAQFTLRIYSNKPLKMKVLDDPPQMTKAALVK-APPGSDSNGFFQYETLF 388
++P+TFEP +EA F LRI+S K + +D + K PP ++ ++ LF
Sbjct: 468 LIPSTFEPHQEADFCLRIFSEKKAITRDMDGNVDIDLPEPPKPTPPDQETEEEQRFRALF 527
Query: 389 LQLADAHRTIDIFELQELLDACLPNDY-IK-------SCVSI----DT------------ 424
Q+A + EL+ +L+A L IK SC +I DT
Sbjct: 528 EQVAGEDMEVTAEELEYVLNAVLQKKKDIKFKKLSLISCKNIISLMDTSGNGKLEFDEFK 587
Query: 425 -----LKHLQLVFKTHAREKMGVLRVERLRDALKDVGFIVPERVISLLVFRYMRKDGMLR 479
LK +F +K G + LR ALK GF + ++ L+V RY ++ L
Sbjct: 588 VFWDKLKQWINLFLRFDADKSGTMSTYELRTALKAAGFQLSSHLLQLIVLRYADEELQLD 647
Query: 480 FGDFVSAVMHL 490
F DF++ ++ L
Sbjct: 648 FDDFLNCLVRL 658
Score = 35.5 bits (78), Expect = 0.45
Identities = 15/38 (39%), Positives = 22/38 (57%)
Query: 11 VGDKWLVSCLGVLYLCKGLFYRVVPADQRMDTSYAGVF 48
+GD WL++ + L L + RV+P DQ YAG+F
Sbjct: 94 LGDCWLLAAIASLTLNQKALARVIPQDQSFGPGYAGIF 131
>X04366-1|CAA27881.1| 714|Homo sapiens protein ( Human mRNA for
calcium activated neutral protease large subunit
(muCANP, calpain, EC 3.4.22.17). ).
Length = 714
Score = 158 bits (383), Expect = 5e-38
Identities = 139/503 (27%), Positives = 226/503 (44%), Gaps = 70/503 (13%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVMPELSDG--SALRTLLDTSSVVTAHYFPPV 106
+++GSYEAL GS +G D TGG+TE + + + L+ S++ +
Sbjct: 197 KVNGSYEALSGGSTSEGFEDFTGGVTEWYELRKAPSDLYQIILKALERGSLLGCS----I 252
Query: 107 TIISVFFLSLPTGIRLVKIRLRRSVINIFQVDTTNEPVYLIRLRRPLGHGETPISHIVLD 166
I SV + T +LVK SV QV+ + V LIR+R P G E +
Sbjct: 253 DISSVLDMEAITFKKLVKGHAY-SVTGAKQVNYRGQVVSLIRMRNPWGEVEWTGAWSD-S 310
Query: 167 TALWKTIPQYERDRLMTASKG--VWMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQKW 224
++ W + YERD+L + WM F DF R F R+E+ +L + ++ +KW
Sbjct: 311 SSEWNNVDPYERDQLRVKMEDGEFWMSFRDFMREFTRLEICNLTPDALKSRTI----RKW 366
Query: 225 QMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPDT-------------VIISLNQ 271
+++G W+RG +AGGCRNY F NPQ +I L+E D V+ + +
Sbjct: 367 NTTLYEGTWRRGSTAGGCRNYPATFWVNPQFKIRLDETDDPDDYGDRESGCSFVLALMQK 426
Query: 272 HSIMEPK------VIGFSVYKMPKFL-----TETANQMFFKRIKSTINSQYTNSRQVSQR 320
H E + IGF+VY++P L F + Q+ N R+VS R
Sbjct: 427 HRRRERRFGRDMETIGFAVYEVPPELVGQPAVHLKRDFFLANASRARSEQFINLREVSTR 486
Query: 321 CQLESGAYLIMPTTFEPREEAQFTLRIYSNKPLKMKVLDDPPQMTKAALVKAPPGSDSNG 380
+L G Y+++P+TFEP +E F LR +S K LDD Q A L S+
Sbjct: 487 FRLPPGEYVVVPSTFEPNKEGDFVLRFFSEKSAGTVELDDQIQ---ANLPDEQVLSEEEI 543
Query: 381 FFQYETLFLQLADAHRTIDIFELQELLDACLPND--------YIKSCVSI---------- 422
++ LF QLA I + EL+ +L+ + ++SC S+
Sbjct: 544 DENFKALFRQLAGEDMEISVKELRTILNRIISKHKDLRTKGFSLESCRSMVNLMDRDGNG 603
Query: 423 -----------DTLKHLQLVFKTHAREKMGVLRVERLRDALKDVGFIVPERVISLLVFRY 471
+ +++ +F+ +K G + +R A++ GF + +++ L++ RY
Sbjct: 604 KLGLVEFNILWNRIRNYLSIFRKFDLDKSGSMSAYEMRMAIESAGFKLNKKLYELIITRY 663
Query: 472 MRKDGMLRFGDFVSAVMHLHRVF 494
D + F +FV ++ L +F
Sbjct: 664 SEPDLAVDFDNFVCCLVRLETMF 686
Score = 37.9 bits (84), Expect = 0.084
Identities = 19/58 (32%), Positives = 31/58 (53%), Gaps = 4/58 (6%)
Query: 11 VGDKWLVSCLGVLYLCKGLFYRVVPADQRMDTSYAGVFRLHGSYEALKYGSLLDGLAD 68
+GD WL++ + L L L +RVVP Q YAG+F ++ ++G +D + D
Sbjct: 112 LGDCWLLAAIASLTLNDTLLHRVVPHGQSFQNGYAGIFH----FQLWQFGEWVDVVVD 165
>BC017200-1|AAH17200.1| 714|Homo sapiens calpain 1, (mu/I) large
subunit protein.
Length = 714
Score = 158 bits (383), Expect = 5e-38
Identities = 139/503 (27%), Positives = 226/503 (44%), Gaps = 70/503 (13%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVMPELSDG--SALRTLLDTSSVVTAHYFPPV 106
+++GSYEAL GS +G D TGG+TE + + + L+ S++ +
Sbjct: 197 KVNGSYEALSGGSTSEGFEDFTGGVTEWYELRKAPSDLYQIILKALERGSLLGCS----I 252
Query: 107 TIISVFFLSLPTGIRLVKIRLRRSVINIFQVDTTNEPVYLIRLRRPLGHGETPISHIVLD 166
I SV + T +LVK SV QV+ + V LIR+R P G E +
Sbjct: 253 DISSVLDMEAITFKKLVKGHAY-SVTGAKQVNYRGQVVSLIRMRNPWGEVEWTGAWSD-S 310
Query: 167 TALWKTIPQYERDRLMTASKG--VWMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQKW 224
++ W + YERD+L + WM F DF R F R+E+ +L + ++ +KW
Sbjct: 311 SSEWNNVDPYERDQLRVKMEDGEFWMSFRDFMREFTRLEICNLTPDALKSRTI----RKW 366
Query: 225 QMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPDT-------------VIISLNQ 271
+++G W+RG +AGGCRNY F NPQ +I L+E D V+ + +
Sbjct: 367 NTTLYEGTWRRGSTAGGCRNYPATFWVNPQFKIRLDETDDPDDYGDRESGCSFVLALMQK 426
Query: 272 HSIMEPK------VIGFSVYKMPKFL-----TETANQMFFKRIKSTINSQYTNSRQVSQR 320
H E + IGF+VY++P L F + Q+ N R+VS R
Sbjct: 427 HRRRERRFGRDMETIGFAVYEVPPELVGQPAVHLKRDFFLANASRARSEQFINLREVSTR 486
Query: 321 CQLESGAYLIMPTTFEPREEAQFTLRIYSNKPLKMKVLDDPPQMTKAALVKAPPGSDSNG 380
+L G Y+++P+TFEP +E F LR +S K LDD Q A L S+
Sbjct: 487 FRLPPGEYVVVPSTFEPNKEGDFVLRFFSEKSAGTVELDDQIQ---ANLPDEQVLSEEEI 543
Query: 381 FFQYETLFLQLADAHRTIDIFELQELLDACLPND--------YIKSCVSI---------- 422
++ LF QLA I + EL+ +L+ + ++SC S+
Sbjct: 544 DENFKALFRQLAGEDMEISVKELRTILNRIISKHKDLRTKGFSLESCRSMVNLMDRDGNG 603
Query: 423 -----------DTLKHLQLVFKTHAREKMGVLRVERLRDALKDVGFIVPERVISLLVFRY 471
+ +++ +F+ +K G + +R A++ GF + +++ L++ RY
Sbjct: 604 KLGLVEFNILWNRIRNYLSIFRKFDLDKSGSMSAYEMRMAIESAGFKLNKKLYELIITRY 663
Query: 472 MRKDGMLRFGDFVSAVMHLHRVF 494
D + F +FV ++ L +F
Sbjct: 664 SEPDLAVDFDNFVCCLVRLETMF 686
Score = 37.9 bits (84), Expect = 0.084
Identities = 19/58 (32%), Positives = 31/58 (53%), Gaps = 4/58 (6%)
Query: 11 VGDKWLVSCLGVLYLCKGLFYRVVPADQRMDTSYAGVFRLHGSYEALKYGSLLDGLAD 68
+GD WL++ + L L L +RVVP Q YAG+F ++ ++G +D + D
Sbjct: 112 LGDCWLLAAIASLTLNDTLLHRVVPHGQSFQNGYAGIFH----FQLWQFGEWVDVVVD 165
>AY796340-1|AAV41878.1| 714|Homo sapiens calpain 1, (mu/I) large
subunit protein.
Length = 714
Score = 158 bits (383), Expect = 5e-38
Identities = 139/503 (27%), Positives = 226/503 (44%), Gaps = 70/503 (13%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVMPELSDG--SALRTLLDTSSVVTAHYFPPV 106
+++GSYEAL GS +G D TGG+TE + + + L+ S++ +
Sbjct: 197 KVNGSYEALSGGSTSEGFEDFTGGVTEWYELRKAPSDLYQIILKALERGSLLGCS----I 252
Query: 107 TIISVFFLSLPTGIRLVKIRLRRSVINIFQVDTTNEPVYLIRLRRPLGHGETPISHIVLD 166
I SV + T +LVK SV QV+ + V LIR+R P G E +
Sbjct: 253 DISSVLDMEAITFKKLVKGHAY-SVTGAKQVNYRGQVVSLIRMRNPWGEVEWTGAWSD-S 310
Query: 167 TALWKTIPQYERDRLMTASKG--VWMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQKW 224
++ W + YERD+L + WM F DF R F R+E+ +L + ++ +KW
Sbjct: 311 SSEWNNVDPYERDQLRVKMEDGEFWMSFRDFMREFTRLEICNLTPDALKSRTI----RKW 366
Query: 225 QMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPDT-------------VIISLNQ 271
+++G W+RG +AGGCRNY F NPQ +I L+E D V+ + +
Sbjct: 367 NTTLYEGTWRRGSTAGGCRNYPATFWVNPQFKIRLDETDDPDDYGDRESGCSFVLALMQK 426
Query: 272 HSIMEPK------VIGFSVYKMPKFL-----TETANQMFFKRIKSTINSQYTNSRQVSQR 320
H E + IGF+VY++P L F + Q+ N R+VS R
Sbjct: 427 HRRRERRFGRDMETIGFAVYEVPPELVGQPAVHLKRDFFLANASRARSEQFINLREVSTR 486
Query: 321 CQLESGAYLIMPTTFEPREEAQFTLRIYSNKPLKMKVLDDPPQMTKAALVKAPPGSDSNG 380
+L G Y+++P+TFEP +E F LR +S K LDD Q A L S+
Sbjct: 487 FRLPPGEYVVVPSTFEPNKEGDFVLRFFSEKSAGTVELDDQIQ---ANLPDEQVLSEEEI 543
Query: 381 FFQYETLFLQLADAHRTIDIFELQELLDACLPND--------YIKSCVSI---------- 422
++ LF QLA I + EL+ +L+ + ++SC S+
Sbjct: 544 DENFKALFRQLAGEDMEISVKELRTILNRIISKHKDLRTKGFSLESCRSMVNLMDRDGNG 603
Query: 423 -----------DTLKHLQLVFKTHAREKMGVLRVERLRDALKDVGFIVPERVISLLVFRY 471
+ +++ +F+ +K G + +R A++ GF + +++ L++ RY
Sbjct: 604 KLGLVEFNILWNRIRNYLSIFRKFDLDKSGSMSAYEMRMAIESAGFKLNKKLYELIITRY 663
Query: 472 MRKDGMLRFGDFVSAVMHLHRVF 494
D + F +FV ++ L +F
Sbjct: 664 SEPDLAVDFDNFVCCLVRLETMF 686
Score = 37.9 bits (84), Expect = 0.084
Identities = 19/58 (32%), Positives = 31/58 (53%), Gaps = 4/58 (6%)
Query: 11 VGDKWLVSCLGVLYLCKGLFYRVVPADQRMDTSYAGVFRLHGSYEALKYGSLLDGLAD 68
+GD WL++ + L L L +RVVP Q YAG+F ++ ++G +D + D
Sbjct: 112 LGDCWLLAAIASLTLNDTLLHRVVPHGQSFQNGYAGIFH----FQLWQFGEWVDVVVD 165
>AY550975-1|AAT52221.1| 714|Homo sapiens cell
proliferation-inducing protein 30 protein.
Length = 714
Score = 158 bits (383), Expect = 5e-38
Identities = 139/503 (27%), Positives = 226/503 (44%), Gaps = 70/503 (13%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVMPELSDG--SALRTLLDTSSVVTAHYFPPV 106
+++GSYEAL GS +G D TGG+TE + + + L+ S++ +
Sbjct: 197 KVNGSYEALSGGSTSEGFEDFTGGVTEWYELRKAPSDLYQIILKALERGSLLGCS----I 252
Query: 107 TIISVFFLSLPTGIRLVKIRLRRSVINIFQVDTTNEPVYLIRLRRPLGHGETPISHIVLD 166
I SV + T +LVK SV QV+ + V LIR+R P G E +
Sbjct: 253 DISSVLDMEAITFKKLVKGHAY-SVTGAKQVNYRGQVVSLIRMRNPWGEVEWTGAWSD-S 310
Query: 167 TALWKTIPQYERDRLMTASKG--VWMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQKW 224
++ W + YERD+L + WM F DF R F R+E+ +L + ++ +KW
Sbjct: 311 SSEWNNVDPYERDQLRVKMEDGEFWMSFRDFMREFTRLEICNLTPDALKSRTI----RKW 366
Query: 225 QMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPDT-------------VIISLNQ 271
+++G W+RG +AGGCRNY F NPQ +I L+E D V+ + +
Sbjct: 367 NTTLYEGTWRRGSTAGGCRNYPATFWVNPQFKIRLDETDDPDDYGDRESGCSFVLALMQK 426
Query: 272 HSIMEPK------VIGFSVYKMPKFL-----TETANQMFFKRIKSTINSQYTNSRQVSQR 320
H E + IGF+VY++P L F + Q+ N R+VS R
Sbjct: 427 HRRRERRFGRDMETIGFAVYEVPPELVGQPAVHLKRDFFLANASRARSEQFINLREVSTR 486
Query: 321 CQLESGAYLIMPTTFEPREEAQFTLRIYSNKPLKMKVLDDPPQMTKAALVKAPPGSDSNG 380
+L G Y+++P+TFEP +E F LR +S K LDD Q A L S+
Sbjct: 487 FRLPPGEYVVVPSTFEPNKEGDFVLRFFSEKSAGTVELDDQIQ---ANLPDEQVLSEEEI 543
Query: 381 FFQYETLFLQLADAHRTIDIFELQELLDACLPND--------YIKSCVSI---------- 422
++ LF QLA I + EL+ +L+ + ++SC S+
Sbjct: 544 DENFKALFRQLAGEDMEISVKELRTILNRIISKHKDLRTKGFSLESCRSMVNLMDRDGNG 603
Query: 423 -----------DTLKHLQLVFKTHAREKMGVLRVERLRDALKDVGFIVPERVISLLVFRY 471
+ +++ +F+ +K G + +R A++ GF + +++ L++ RY
Sbjct: 604 KLGLVEFNILWNRIRNYLSIFRKFDLDKSGSMSAYEMRMAIESAGFKLNKKLYELIITRY 663
Query: 472 MRKDGMLRFGDFVSAVMHLHRVF 494
D + F +FV ++ L +F
Sbjct: 664 SEPDLAVDFDNFVCCLVRLETMF 686
Score = 37.9 bits (84), Expect = 0.084
Identities = 19/58 (32%), Positives = 31/58 (53%), Gaps = 4/58 (6%)
Query: 11 VGDKWLVSCLGVLYLCKGLFYRVVPADQRMDTSYAGVFRLHGSYEALKYGSLLDGLAD 68
+GD WL++ + L L L +RVVP Q YAG+F ++ ++G +D + D
Sbjct: 112 LGDCWLLAAIASLTLNDTLLHRVVPHGQSFQNGYAGIFH----FQLWQFGEWVDVVVD 165
>BC075862-1|AAH75862.1| 714|Homo sapiens CAPN1 protein protein.
Length = 714
Score = 157 bits (382), Expect = 7e-38
Identities = 139/503 (27%), Positives = 226/503 (44%), Gaps = 70/503 (13%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVMPELSDG--SALRTLLDTSSVVTAHYFPPV 106
+++GSYEAL GS +G D TGG+TE + + + L+ S++ +
Sbjct: 197 KVNGSYEALSGGSTSEGFEDFTGGVTEWYELRKAPSDLYQIILKALERGSLLGCS----I 252
Query: 107 TIISVFFLSLPTGIRLVKIRLRRSVINIFQVDTTNEPVYLIRLRRPLGHGETPISHIVLD 166
I SV + T +LVK SV QV+ + V LIR+R P G E +
Sbjct: 253 DISSVLDMEAITFKKLVKGHAY-SVTGAKQVNYRGQVVSLIRMRNPWGEVEWTGAWSD-S 310
Query: 167 TALWKTIPQYERDRLMTASKG--VWMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQKW 224
++ W + YERD+L + WM F DF R F R+E+ +L + ++ +KW
Sbjct: 311 SSEWNNVDPYERDQLRVKMEDGEFWMSFRDFMREFTRLEICNLTPDALKSRTI----RKW 366
Query: 225 QMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPDT-------------VIISLNQ 271
+++G W+RG +AGGCRNY F NPQ +I L+E D V+ + +
Sbjct: 367 NTTLYEGTWRRGSTAGGCRNYPATFWVNPQFKIRLDETDDPDDYGDRESGCSFVLALMQK 426
Query: 272 HSIME------PKVIGFSVYKMPKFL-----TETANQMFFKRIKSTINSQYTNSRQVSQR 320
H E + IGF+VY++P L F + Q+ N R+VS R
Sbjct: 427 HRRRERPFGRDMETIGFAVYEVPPELVGQPAVHLKRDFFLANASRARSEQFINLREVSTR 486
Query: 321 CQLESGAYLIMPTTFEPREEAQFTLRIYSNKPLKMKVLDDPPQMTKAALVKAPPGSDSNG 380
+L G Y+++P+TFEP +E F LR +S K LDD Q A L S+
Sbjct: 487 FRLPPGEYVVVPSTFEPNKEGDFVLRFFSEKSAGTVELDDQIQ---ANLPDEQVLSEEEI 543
Query: 381 FFQYETLFLQLADAHRTIDIFELQELLDACLPND--------YIKSCVSI---------- 422
++ LF QLA I + EL+ +L+ + ++SC S+
Sbjct: 544 DENFKALFRQLAGEDMEISVKELRTILNRIISKHKDLRTKGFSLESCRSMVNLMDRDGNG 603
Query: 423 -----------DTLKHLQLVFKTHAREKMGVLRVERLRDALKDVGFIVPERVISLLVFRY 471
+ +++ +F+ +K G + +R A++ GF + +++ L++ RY
Sbjct: 604 KLGLVEFNILWNRIRNYLSIFRKFDLDKSGSMSAYEMRMAIESAGFKLNKKLYELIITRY 663
Query: 472 MRKDGMLRFGDFVSAVMHLHRVF 494
D + F +FV ++ L +F
Sbjct: 664 SEPDLAVDFDNFVCCLVRLETMF 686
Score = 37.9 bits (84), Expect = 0.084
Identities = 19/58 (32%), Positives = 31/58 (53%), Gaps = 4/58 (6%)
Query: 11 VGDKWLVSCLGVLYLCKGLFYRVVPADQRMDTSYAGVFRLHGSYEALKYGSLLDGLAD 68
+GD WL++ + L L L +RVVP Q YAG+F ++ ++G +D + D
Sbjct: 112 LGDCWLLAAIASLTLNDTLLHRVVPHGQSFQNGYAGIFH----FQLWQFGEWVDVVVD 165
>BC008751-1|AAH08751.1| 714|Homo sapiens calpain 1, (mu/I) large
subunit protein.
Length = 714
Score = 157 bits (382), Expect = 7e-38
Identities = 139/503 (27%), Positives = 225/503 (44%), Gaps = 70/503 (13%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVMPELSDG--SALRTLLDTSSVVTAHYFPPV 106
+++GSYEAL GS +G D TGG+TE + + + L+ S++ +
Sbjct: 197 KVNGSYEALSGGSTSEGFEDFTGGVTEWYELRKAPSDLYQIILKALERGSLLGCS----I 252
Query: 107 TIISVFFLSLPTGIRLVKIRLRRSVINIFQVDTTNEPVYLIRLRRPLGHGETPISHIVLD 166
I SV + T +LVK SV QV+ + V LIR+R P G E +
Sbjct: 253 DISSVLDMEAITFKKLVKGHAY-SVTGAKQVNYRGQVVSLIRMRNPWGEVEWTGAWSD-S 310
Query: 167 TALWKTIPQYERDRLMTASKG--VWMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQKW 224
++ W + YERD+L + WM F DF R F R+E+ +L + ++ +KW
Sbjct: 311 SSEWNNVDPYERDQLRVKMEDGEFWMSFRDFMREFTRLEICNLTPDALKSRTI----RKW 366
Query: 225 QMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPDT-------------VIISLNQ 271
+++G W+RG +AGGCRNY F NPQ +I L+E D V+ + +
Sbjct: 367 NTTLYEGTWRRGSTAGGCRNYPATFWVNPQFKIRLDETDDPDDYGDRESGCSFVLALMQK 426
Query: 272 HSIMEPK------VIGFSVYKMPKFL-----TETANQMFFKRIKSTINSQYTNSRQVSQR 320
H E + IGF+VY++P L F + Q+ N R+VS R
Sbjct: 427 HRRRERRFGRDMETIGFAVYEVPPELVGQPAVHLKRDFFLANASRARSEQFINLREVSTR 486
Query: 321 CQLESGAYLIMPTTFEPREEAQFTLRIYSNKPLKMKVLDDPPQMTKAALVKAPPGSDSNG 380
+L G Y+++P+TFEP +E F LR +S K LDD Q A L S+
Sbjct: 487 FRLPPGEYVVVPSTFEPNKEGDFVLRFFSEKSAGTVELDDQIQ---ANLPDEQVLSEEEI 543
Query: 381 FFQYETLFLQLADAHRTIDIFELQELLDACLPND--------YIKSCVSI---------- 422
+ LF QLA I + EL+ +L+ + ++SC S+
Sbjct: 544 DENFNALFRQLAGEDMEISVKELRTILNRIISKHKDLRTKGFSLESCRSMVNLMDRDGNG 603
Query: 423 -----------DTLKHLQLVFKTHAREKMGVLRVERLRDALKDVGFIVPERVISLLVFRY 471
+ +++ +F+ +K G + +R A++ GF + +++ L++ RY
Sbjct: 604 KLGLVEFNILWNRIRNYLSIFRKFDLDKSGSMSAYEMRMAIESAGFKLNKKLYELIITRY 663
Query: 472 MRKDGMLRFGDFVSAVMHLHRVF 494
D + F +FV ++ L +F
Sbjct: 664 SEPDLAVDFDNFVCCLVRLETMF 686
Score = 37.9 bits (84), Expect = 0.084
Identities = 19/58 (32%), Positives = 31/58 (53%), Gaps = 4/58 (6%)
Query: 11 VGDKWLVSCLGVLYLCKGLFYRVVPADQRMDTSYAGVFRLHGSYEALKYGSLLDGLAD 68
+GD WL++ + L L L +RVVP Q YAG+F ++ ++G +D + D
Sbjct: 112 LGDCWLLAAIASLTLNDTLLHRVVPHGQSFQNGYAGIFH----FQLWQFGEWVDVVVD 165
>BC021303-1|AAH21303.1| 700|Homo sapiens calpain 2, (m/II) large
subunit protein.
Length = 700
Score = 149 bits (362), Expect = 2e-35
Identities = 145/511 (28%), Positives = 233/511 (45%), Gaps = 70/511 (13%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITE--SIVMPELSDGSALRTLLDTSSVVTAHYFPPV 106
+++G YEAL G+ +G D TGGI E + P + ++ L S++ +
Sbjct: 187 KINGCYEALSGGATTEGFEDFTGGIAEWYELKKPPPNLFKIIQKALQKGSLLGCS----I 242
Query: 107 TIISVFFLSLPTGIRLVKIRLRRSVINIFQVDTTNEPVYLIRLRRPLGHGETPISHIVLD 166
I S T +LVK SV +V++ LIR+R P G E +
Sbjct: 243 DITSAADSEAITFQKLVKGHAY-SVTGAEEVESNGSLQKLIRIRNPWGEVEWT-GRWNDN 300
Query: 167 TALWKTIPQYERDRLMTASKG--VWMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQKW 224
W TI ER+RL + WM FSDF R + R+E+ +L +T L+ +KW
Sbjct: 301 CPSWNTIDPEERERLTRRHEDGEFWMSFSDFLRHYSRLEICNLTPDT----LTSDTYKKW 356
Query: 225 QMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPD----------TVIISLNQ-HS 273
++ G W+RG +AGGCRNY N F NPQ I L E D T ++ L Q H
Sbjct: 357 KLTKMDGNWRRGSTAGGCRNYPNTFWMNPQYLIKLEEEDEDEEDGESGCTFLVGLIQKHR 416
Query: 274 IMEPKV------IGFSVYKMPKFLTETAN----QMFFKRIKSTINSQ-YTNSRQVSQRCQ 322
+ K+ IGF +Y++P+ L+ N + FF ++ S + N R+V R +
Sbjct: 417 RRQRKMGEDMHTIGFGIYEVPEELSGQTNIHLSKNFFLTNRARERSDTFINLREVLNRFK 476
Query: 323 LESGAYLIMPTTFEPREEAQFTLRIYSNKPLKMKVLDDPPQMTKAALVKAPPGSDSNGFF 382
L G Y+++P+TFEP ++ F +R++S K + +DD + + D +GF
Sbjct: 477 LPPGEYILVPSTFEPNKDGDFCIRVFSEKKADYQAVDDEIEANLEEFDISEDDID-DGF- 534
Query: 383 QYETLFLQLADAHRTIDIFELQELLDACLP--NDYIKSCVSIDTLKHLQLVFKTHAREKM 440
LF QLA I FELQ +L L D SI+T K + + + K+
Sbjct: 535 --RRLFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKL 592
Query: 441 GV-------------------LRVER--------LRDALKDVGFIVPERVISLLVFRYMR 473
G+ + V+R +R AL++ GF +P ++ ++V R+
Sbjct: 593 GLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARFAD 652
Query: 474 KDGMLRFGDFVSAVMHLHRVFVQVYDFIQPE 504
++ F +FV ++ L +F +++ + PE
Sbjct: 653 DQLIIDFDNFVRCLVRLETLF-KIFKQLDPE 682
Score = 37.1 bits (82), Expect = 0.15
Identities = 18/58 (31%), Positives = 33/58 (56%), Gaps = 4/58 (6%)
Query: 11 VGDKWLVSCLGVLYLCKGLFYRVVPADQRMDTSYAGVFRLHGSYEALKYGSLLDGLAD 68
+GD WL++ + L L + + RVVP +Q +YAG+F ++ +YG ++ + D
Sbjct: 102 LGDCWLLAAIASLTLNEEILARVVPLNQSFQENYAGIFH----FQFWQYGEWVEVVVD 155
>AY835586-1|AAV80421.1| 700|Homo sapiens calpain 2, (m/II) large
subunit protein.
Length = 700
Score = 149 bits (362), Expect = 2e-35
Identities = 145/511 (28%), Positives = 233/511 (45%), Gaps = 70/511 (13%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITE--SIVMPELSDGSALRTLLDTSSVVTAHYFPPV 106
+++G YEAL G+ +G D TGGI E + P + ++ L S++ +
Sbjct: 187 KINGCYEALSGGATTEGFEDFTGGIAEWYELKKPPPNLFKIIQKALQKGSLLGCS----I 242
Query: 107 TIISVFFLSLPTGIRLVKIRLRRSVINIFQVDTTNEPVYLIRLRRPLGHGETPISHIVLD 166
I S T +LVK SV +V++ LIR+R P G E +
Sbjct: 243 DITSAADSEAITFQKLVKGHAY-SVTGAEEVESNGSLQKLIRIRNPWGEVEWT-GRWNDN 300
Query: 167 TALWKTIPQYERDRLMTASKG--VWMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQKW 224
W TI ER+RL + WM FSDF R + R+E+ +L +T L+ +KW
Sbjct: 301 CPSWNTIDPEERERLTRRHEDGEFWMSFSDFLRHYSRLEICNLTPDT----LTSDTYKKW 356
Query: 225 QMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPD----------TVIISLNQ-HS 273
++ G W+RG +AGGCRNY N F NPQ I L E D T ++ L Q H
Sbjct: 357 KLTKMDGNWRRGSTAGGCRNYPNTFWMNPQYLIKLEEEDEDEEDGESGCTFLVGLIQKHR 416
Query: 274 IMEPKV------IGFSVYKMPKFLTETAN----QMFFKRIKSTINSQ-YTNSRQVSQRCQ 322
+ K+ IGF +Y++P+ L+ N + FF ++ S + N R+V R +
Sbjct: 417 RRQRKMGEDMHTIGFGIYEVPEELSGQTNIHLSKNFFLTNRARERSDTFINLREVLNRFK 476
Query: 323 LESGAYLIMPTTFEPREEAQFTLRIYSNKPLKMKVLDDPPQMTKAALVKAPPGSDSNGFF 382
L G Y+++P+TFEP ++ F +R++S K + +DD + + D +GF
Sbjct: 477 LPPGEYILVPSTFEPNKDGDFCIRVFSEKKADYQAVDDEIEANLEEFDISEDDID-DGF- 534
Query: 383 QYETLFLQLADAHRTIDIFELQELLDACLP--NDYIKSCVSIDTLKHLQLVFKTHAREKM 440
LF QLA I FELQ +L L D SI+T K + + + K+
Sbjct: 535 --RRLFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKL 592
Query: 441 GV-------------------LRVER--------LRDALKDVGFIVPERVISLLVFRYMR 473
G+ + V+R +R AL++ GF +P ++ ++V R+
Sbjct: 593 GLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARFAD 652
Query: 474 KDGMLRFGDFVSAVMHLHRVFVQVYDFIQPE 504
++ F +FV ++ L +F +++ + PE
Sbjct: 653 DQLIIDFDNFVRCLVRLETLF-KIFKQLDPE 682
Score = 37.1 bits (82), Expect = 0.15
Identities = 18/58 (31%), Positives = 33/58 (56%), Gaps = 4/58 (6%)
Query: 11 VGDKWLVSCLGVLYLCKGLFYRVVPADQRMDTSYAGVFRLHGSYEALKYGSLLDGLAD 68
+GD WL++ + L L + + RVVP +Q +YAG+F ++ +YG ++ + D
Sbjct: 102 LGDCWLLAAIASLTLNEEILARVVPLNQSFQENYAGIFH----FQFWQYGEWVEVVVD 155
>AL591291-1|CAI17215.1| 664|Homo sapiens calpain 9 protein.
Length = 664
Score = 149 bits (361), Expect = 2e-35
Identities = 144/488 (29%), Positives = 222/488 (45%), Gaps = 80/488 (16%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVMPELSDG--SALRTLLDTSSVVTAHYFPPV 106
+L+GSYEALK GS ++ + D TGG+ E+ E + L L S++ +
Sbjct: 179 KLNGSYEALKGGSAIEAMEDFTGGVAETFQTKEAPENFYEILEKALKRGSLLGCF----I 234
Query: 107 TIISVFFLSLPTGIRLVKIRLRRSVINIFQVDTTNEPVYLIRLRRPLGHGETPISHIVLD 166
S T L+K SV I QV + + LIR+R P G E S
Sbjct: 235 DTRSAAESEARTPFGLIKGHAY-SVTGIDQVSFRGQRIELIRIRNPWGQVEWNGS----- 288
Query: 167 TALWKTIPQYERDRLMTASKGVWMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQKWQM 226
W DR M F DF+ F ++E+ +L + L KW++
Sbjct: 289 ---WS-------DR---------MAFKDFKAHFDKVEICNLTPDA----LEEDAIHKWEV 325
Query: 227 KMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPD------TVIISLNQHSIMEPK-- 278
+HQG W RG +AGGCRN+++ F TNPQ+++ L E D + +++L Q + K
Sbjct: 326 TVHQGSWVRGSTAGGCRNFLDTFWTNPQIKLSLTEKDEGQEECSFLVALMQKDRRKLKRF 385
Query: 279 -----VIGFSVYKMPKFLTETANQMFFKRIKSTINSQ-YTNSRQVSQRCQLESGAYLIMP 332
IG+++Y+ P E N+ FF+ S S+ + N R+VS R +L G Y+++P
Sbjct: 386 GANVLTIGYAIYECPD-KDEHLNKDFFRYHASRARSKTFINLREVSDRFKLPPGEYILIP 444
Query: 333 TTFEPREEAQFTLRIYSNKPLKMKVLDDPPQMTKAALVK-APPGSDSNGFFQYETLFLQL 391
+TFEP +EA F LRI+S K + +D + K PP ++ ++ LF Q+
Sbjct: 445 STFEPHQEADFCLRIFSEKKAITRDMDGNVDIDLPEPPKPTPPDQETEEEQRFRALFEQV 504
Query: 392 ADAHRTIDIFELQELLDACLPNDY-IK-------SCVSI----DT--------------- 424
A + EL+ +L+A L IK SC +I DT
Sbjct: 505 AGEDMEVTAEELEYVLNAVLQKKKDIKFKKLSLISCKNIISLMDTSGNGKLEFDEFKVFW 564
Query: 425 --LKHLQLVFKTHAREKMGVLRVERLRDALKDVGFIVPERVISLLVFRYMRKDGMLRFGD 482
LK +F +K G + LR ALK GF + ++ L+V RY ++ L F D
Sbjct: 565 DKLKQWINLFLRFDADKSGTMSTYELRTALKAAGFQLSSHLLQLIVLRYADEELQLDFDD 624
Query: 483 FVSAVMHL 490
F++ ++ L
Sbjct: 625 FLNCLVRL 632
Score = 35.5 bits (78), Expect = 0.45
Identities = 15/38 (39%), Positives = 22/38 (57%)
Query: 11 VGDKWLVSCLGVLYLCKGLFYRVVPADQRMDTSYAGVF 48
+GD WL++ + L L + RV+P DQ YAG+F
Sbjct: 94 LGDCWLLAAIASLTLNQKALARVIPQDQSFGPGYAGIF 131
>AL512328-2|CAI14866.1| 664|Homo sapiens calpain 9 protein.
Length = 664
Score = 149 bits (361), Expect = 2e-35
Identities = 144/488 (29%), Positives = 222/488 (45%), Gaps = 80/488 (16%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVMPELSDG--SALRTLLDTSSVVTAHYFPPV 106
+L+GSYEALK GS ++ + D TGG+ E+ E + L L S++ +
Sbjct: 179 KLNGSYEALKGGSAIEAMEDFTGGVAETFQTKEAPENFYEILEKALKRGSLLGCF----I 234
Query: 107 TIISVFFLSLPTGIRLVKIRLRRSVINIFQVDTTNEPVYLIRLRRPLGHGETPISHIVLD 166
S T L+K SV I QV + + LIR+R P G E S
Sbjct: 235 DTRSAAESEARTPFGLIKGHAY-SVTGIDQVSFRGQRIELIRIRNPWGQVEWNGS----- 288
Query: 167 TALWKTIPQYERDRLMTASKGVWMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQKWQM 226
W DR M F DF+ F ++E+ +L + L KW++
Sbjct: 289 ---WS-------DR---------MAFKDFKAHFDKVEICNLTPDA----LEEDAIHKWEV 325
Query: 227 KMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPD------TVIISLNQHSIMEPK-- 278
+HQG W RG +AGGCRN+++ F TNPQ+++ L E D + +++L Q + K
Sbjct: 326 TVHQGSWVRGSTAGGCRNFLDTFWTNPQIKLSLTEKDEGQEECSFLVALMQKDRRKLKRF 385
Query: 279 -----VIGFSVYKMPKFLTETANQMFFKRIKSTINSQ-YTNSRQVSQRCQLESGAYLIMP 332
IG+++Y+ P E N+ FF+ S S+ + N R+VS R +L G Y+++P
Sbjct: 386 GANVLTIGYAIYECPD-KDEHLNKDFFRYHASRARSKTFINLREVSDRFKLPPGEYILIP 444
Query: 333 TTFEPREEAQFTLRIYSNKPLKMKVLDDPPQMTKAALVK-APPGSDSNGFFQYETLFLQL 391
+TFEP +EA F LRI+S K + +D + K PP ++ ++ LF Q+
Sbjct: 445 STFEPHQEADFCLRIFSEKKAITRDMDGNVDIDLPEPPKPTPPDQETEEEQRFRALFEQV 504
Query: 392 ADAHRTIDIFELQELLDACLPNDY-IK-------SCVSI----DT--------------- 424
A + EL+ +L+A L IK SC +I DT
Sbjct: 505 AGEDMEVTAEELEYVLNAVLQKKKDIKFKKLSLISCKNIISLMDTSGNGKLEFDEFKVFW 564
Query: 425 --LKHLQLVFKTHAREKMGVLRVERLRDALKDVGFIVPERVISLLVFRYMRKDGMLRFGD 482
LK +F +K G + LR ALK GF + ++ L+V RY ++ L F D
Sbjct: 565 DKLKQWINLFLRFDADKSGTMSTYELRTALKAAGFQLSSHLLQLIVLRYADEELQLDFDD 624
Query: 483 FVSAVMHL 490
F++ ++ L
Sbjct: 625 FLNCLVRL 632
Score = 35.5 bits (78), Expect = 0.45
Identities = 15/38 (39%), Positives = 22/38 (57%)
Query: 11 VGDKWLVSCLGVLYLCKGLFYRVVPADQRMDTSYAGVF 48
+GD WL++ + L L + RV+P DQ YAG+F
Sbjct: 94 LGDCWLLAAIASLTLNQKALARVIPQDQSFGPGYAGIF 131
>AB038463-1|BAA92137.1| 664|Homo sapiens GC36 protein.
Length = 664
Score = 149 bits (361), Expect = 2e-35
Identities = 144/488 (29%), Positives = 222/488 (45%), Gaps = 80/488 (16%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVMPELSDG--SALRTLLDTSSVVTAHYFPPV 106
+L+GSYEALK GS ++ + D TGG+ E+ E + L L S++ +
Sbjct: 179 KLNGSYEALKGGSAIEAMEDFTGGVAETFQTKEAPENFYEILEKALKRGSLLGCF----I 234
Query: 107 TIISVFFLSLPTGIRLVKIRLRRSVINIFQVDTTNEPVYLIRLRRPLGHGETPISHIVLD 166
S T L+K SV I QV + + LIR+R P G E S
Sbjct: 235 DTRSAAESEARTPFGLIKGHAY-SVTGIDQVSFRGQRIELIRIRNPWGQVEWNGS----- 288
Query: 167 TALWKTIPQYERDRLMTASKGVWMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQKWQM 226
W DR M F DF+ F ++E+ +L + L KW++
Sbjct: 289 ---WS-------DR---------MAFKDFKAHFDKVEICNLTPDA----LEEDAIHKWEV 325
Query: 227 KMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPD------TVIISLNQHSIMEPK-- 278
+HQG W RG +AGGCRN+++ F TNPQ+++ L E D + +++L Q + K
Sbjct: 326 TVHQGSWVRGSTAGGCRNFLDTFWTNPQIKLSLTEKDEGQEECSFLVALMQKDRRKLKRF 385
Query: 279 -----VIGFSVYKMPKFLTETANQMFFKRIKSTINSQ-YTNSRQVSQRCQLESGAYLIMP 332
IG+++Y+ P E N+ FF+ S S+ + N R+VS R +L G Y+++P
Sbjct: 386 GANVLTIGYAIYECPD-KDEHLNKDFFRYHASRARSKTFINLREVSDRFKLPPGEYILIP 444
Query: 333 TTFEPREEAQFTLRIYSNKPLKMKVLDDPPQMTKAALVK-APPGSDSNGFFQYETLFLQL 391
+TFEP +EA F LRI+S K + +D + K PP ++ ++ LF Q+
Sbjct: 445 STFEPHQEADFCLRIFSEKKAITRDMDGNVDIDLPEPPKPTPPDQETEEEQRFRALFEQV 504
Query: 392 ADAHRTIDIFELQELLDACLPNDY-IK-------SCVSI----DT--------------- 424
A + EL+ +L+A L IK SC +I DT
Sbjct: 505 AGEDMEVTAEELEYVLNAVLQKKKDIKFKKLSLISCKNIISLMDTSGNGKLEFDEFKVFW 564
Query: 425 --LKHLQLVFKTHAREKMGVLRVERLRDALKDVGFIVPERVISLLVFRYMRKDGMLRFGD 482
LK +F +K G + LR ALK GF + ++ L+V RY ++ L F D
Sbjct: 565 DKLKQWINLFLRFDADKSGTMSTYELRTALKAAGFQLSSHLLQLIVLRYADEELQLDFDD 624
Query: 483 FVSAVMHL 490
F++ ++ L
Sbjct: 625 FLNCLVRL 632
Score = 35.5 bits (78), Expect = 0.45
Identities = 15/38 (39%), Positives = 22/38 (57%)
Query: 11 VGDKWLVSCLGVLYLCKGLFYRVVPADQRMDTSYAGVF 48
+GD WL++ + L L + RV+P DQ YAG+F
Sbjct: 94 LGDCWLLAAIASLTLNQKALARVIPQDQSFGPGYAGIF 131
>AB209855-1|BAD93092.1| 729|Homo sapiens Calpain 2, large
[catalytic] subunit precursor variant protein.
Length = 729
Score = 148 bits (358), Expect = 5e-35
Identities = 145/511 (28%), Positives = 232/511 (45%), Gaps = 70/511 (13%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITE--SIVMPELSDGSALRTLLDTSSVVTAHYFPPV 106
+++G YEAL G+ +G D TGGI E P + ++ L S++ +
Sbjct: 216 KINGCYEALSGGATTEGFEDFTGGIAEWYESKKPPPNLFKIIQKALQKGSLLGCS----I 271
Query: 107 TIISVFFLSLPTGIRLVKIRLRRSVINIFQVDTTNEPVYLIRLRRPLGHGETPISHIVLD 166
I S T +LVK SV +V++ LIR+R P G E +
Sbjct: 272 DITSAADSEAITFQKLVKGHAY-SVTGAEEVESNGSLQKLIRIRNPWGEVEWT-GRWNDN 329
Query: 167 TALWKTIPQYERDRLMTASKG--VWMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQKW 224
W TI ER+RL + WM FSDF R + R+E+ +L +T L+ +KW
Sbjct: 330 CPSWNTIDPEERERLTRRHEDGEFWMSFSDFLRHYSRLEICNLTPDT----LTSDTYKKW 385
Query: 225 QMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPD----------TVIISLNQ-HS 273
++ G W+RG +AGGCRNY N F NPQ I L E D T ++ L Q H
Sbjct: 386 KLTKMDGNWRRGSTAGGCRNYPNTFWMNPQYLIKLEEEDEDEEDGESGCTFLVGLIQKHR 445
Query: 274 IMEPKV------IGFSVYKMPKFLTETAN----QMFFKRIKSTINSQ-YTNSRQVSQRCQ 322
+ K+ IGF +Y++P+ L+ N + FF ++ S + N R+V R +
Sbjct: 446 RRQRKMGEDMHTIGFGIYEVPEELSGQTNIHLSKNFFLTNRARERSDTFINLREVLNRFK 505
Query: 323 LESGAYLIMPTTFEPREEAQFTLRIYSNKPLKMKVLDDPPQMTKAALVKAPPGSDSNGFF 382
L G Y+++P+TFEP ++ F +R++S K + +DD + + D +GF
Sbjct: 506 LPPGEYILVPSTFEPNKDGDFCIRVFSEKKADYQAVDDEIEANLEEFDISEDDID-DGF- 563
Query: 383 QYETLFLQLADAHRTIDIFELQELLDACLP--NDYIKSCVSIDTLKHLQLVFKTHAREKM 440
LF QLA I FELQ +L L D SI+T K + + + K+
Sbjct: 564 --RRLFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKL 621
Query: 441 GV-------------------LRVER--------LRDALKDVGFIVPERVISLLVFRYMR 473
G+ + V+R +R AL++ GF +P ++ ++V R+
Sbjct: 622 GLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARFAD 681
Query: 474 KDGMLRFGDFVSAVMHLHRVFVQVYDFIQPE 504
++ F +FV ++ L +F +++ + PE
Sbjct: 682 DQLIIDFDNFVRCLVRLETLF-KIFKQLDPE 711
Score = 36.3 bits (80), Expect = 0.26
Identities = 18/58 (31%), Positives = 33/58 (56%), Gaps = 4/58 (6%)
Query: 11 VGDKWLVSCLGVLYLCKGLFYRVVPADQRMDTSYAGVFRLHGSYEALKYGSLLDGLAD 68
+GD WL++ + L L + + RVVP +Q +YAG+F ++ +YG ++ + D
Sbjct: 131 LGDCWLLAAIASLTLNEEILARVVPLNQCFQENYAGIFH----FQFWQYGEWVEVVVD 184
>M23254-1|AAA35645.1| 700|Homo sapiens neutral protease large
subunit protein.
Length = 700
Score = 147 bits (357), Expect = 7e-35
Identities = 143/511 (27%), Positives = 230/511 (45%), Gaps = 70/511 (13%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITE--SIVMPELSDGSALRTLLDTSSVVTAHYFPPV 106
+++G YEAL G+ +G D TGGI E + P + ++ L S++ +
Sbjct: 187 KINGCYEALSGGATTEGFEDFTGGIAEWYELKKPPPNLFKIIQKALQKGSLLGCS----I 242
Query: 107 TIISVFFLSLPTGIRLVKIRLRRSVINIFQVDTTNEPVYLIRLRRPLGHGETPISHIVLD 166
I S T +LVK SV +V++ LIR+R P G E +
Sbjct: 243 DITSAADSEAITFQKLVKGHAY-SVTGAEEVESNGSLQKLIRIRNPWGEVEWT-GRWNDN 300
Query: 167 TALWKTIPQYERDRLMTASKG--VWMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQKW 224
W TI ER+RL + WM FSDF R + R+E+ +L +T L+ +KW
Sbjct: 301 CPSWNTIDPEERERLTRRHEDGEFWMSFSDFLRHYSRLEICNLTPDT----LTSDTYKKW 356
Query: 225 QMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPD----------TVIISLNQ-HS 273
++ G W+RG +AGGCRNY N F NPQ I L E D T ++ L Q H
Sbjct: 357 KLTKMDGNWRRGSTAGGCRNYPNTFWMNPQYLIKLEEEDEDEEDGESGCTFLVGLIQKHR 416
Query: 274 IMEPKV------IGFSVYKMPKFLTETAN----QMFFKRIKSTINSQ-YTNSRQVSQRCQ 322
+ K+ IGF +Y++P+ L+ N + FF ++ S + N R+V R +
Sbjct: 417 RRQRKMGEDMHTIGFGIYEVPEELSGQTNIHLSKNFFLTNRARERSDTFINLREVLNRFK 476
Query: 323 LESGAYLIMPTTFEPREEAQFTLRIYSNKPLKMKVLDDPPQMTKAALVKAPPGSDSNGFF 382
L G Y+++P+TFEP ++ F +R++S K + +DD + + D
Sbjct: 477 LPPGEYILVPSTFEPNKDGDFCIRVFSEKKADYQAVDDEIEANLEEFDISEDDIDDG--- 533
Query: 383 QYETLFLQLADAHRTIDIFELQELLDACLP--NDYIKSCVSIDTLKHLQLVFKTHAREKM 440
LF QLA I FELQ +L L D SI+T K + + + K+
Sbjct: 534 -VRRLFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKL 592
Query: 441 GV-------------------LRVER--------LRDALKDVGFIVPERVISLLVFRYMR 473
G+ + V+R +R AL++ GF +P ++ ++V R+
Sbjct: 593 GLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARFAD 652
Query: 474 KDGMLRFGDFVSAVMHLHRVFVQVYDFIQPE 504
++ F +FV ++ L +F +++ + PE
Sbjct: 653 DQLIIDFDNFVRCLVRLETLF-KIFKQLDPE 682
Score = 37.1 bits (82), Expect = 0.15
Identities = 18/58 (31%), Positives = 33/58 (56%), Gaps = 4/58 (6%)
Query: 11 VGDKWLVSCLGVLYLCKGLFYRVVPADQRMDTSYAGVFRLHGSYEALKYGSLLDGLAD 68
+GD WL++ + L L + + RVVP +Q +YAG+F ++ +YG ++ + D
Sbjct: 102 LGDCWLLAAIASLTLNEEILARVVPLNQSFQENYAGIFH----FQFWQYGEWVEVVVD 155
>AF261089-1|AAF99682.1| 700|Homo sapiens calpain large polypeptide
L2 protein.
Length = 700
Score = 147 bits (356), Expect = 9e-35
Identities = 143/511 (27%), Positives = 229/511 (44%), Gaps = 70/511 (13%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITE--SIVMPELSDGSALRTLLDTSSVVTAHYFPPV 106
+++G YEAL G+ +G D TGGI E + P + ++ L S++ +
Sbjct: 187 KINGCYEALSGGATTEGFEDFTGGIAEWYELKKPPPNLFKIIQKALQKGSLLGCS----I 242
Query: 107 TIISVFFLSLPTGIRLVKIRLRRSVINIFQVDTTNEPVYLIRLRRPLGHGETPISHIVLD 166
I S T +LVK SV +V++ LIR+R P G E
Sbjct: 243 DITSAADSEAITFKKLVKGHAY-SVTGAEEVESNGSLQKLIRIRNPWGEVEWT-GRWNDS 300
Query: 167 TALWKTIPQYERDRLMTASKG--VWMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQKW 224
W TI ER+RL + WM FSDF R + R+E+ +L +T L+ +KW
Sbjct: 301 CPSWNTIDPEERERLTRRHEDGEFWMSFSDFLRHYSRLEICNLTPDT----LTSDTYKKW 356
Query: 225 QMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPD----------TVIISLNQ-HS 273
++ G W+RG +AGGCRNY N F NPQ I L E D T ++ L Q H
Sbjct: 357 KLTKMDGNWRRGSTAGGCRNYPNTFWMNPQYLIKLEEEDEDEEDGESGCTFLVGLIQKHR 416
Query: 274 IMEPKV------IGFSVYKMPKFLTETAN----QMFFKRIKSTINSQ-YTNSRQVSQRCQ 322
+ K+ IGF +Y++P+ L+ N + FF ++ S + N R+V R +
Sbjct: 417 RRQRKMGEDMHTIGFGIYEVPEELSGQTNIHLSKNFFLTNRARERSDTFINLREVLNRFK 476
Query: 323 LESGAYLIMPTTFEPREEAQFTLRIYSNKPLKMKVLDDPPQMTKAALVKAPPGSDSNGFF 382
L G Y+++P+TFEP ++ F +R++S K + +DD + + D
Sbjct: 477 LPPGEYILVPSTFEPNKDGDFCIRVFSEKKADYQAVDDEIEANLEEFDISEDDIDDG--- 533
Query: 383 QYETLFLQLADAHRTIDIFELQELLDACLP--NDYIKSCVSIDTLKHLQLVFKTHAREKM 440
LF QLA I FELQ +L L D SI+T K + + + K+
Sbjct: 534 -VRRLFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKL 592
Query: 441 GV-------------------LRVER--------LRDALKDVGFIVPERVISLLVFRYMR 473
G+ + V+R +R AL++ GF +P ++ ++V R+
Sbjct: 593 GLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARFAD 652
Query: 474 KDGMLRFGDFVSAVMHLHRVFVQVYDFIQPE 504
++ F +FV ++ L +F +++ + PE
Sbjct: 653 DQLIIDFDNFVRCLVRLETLF-KIFKQLDPE 682
Score = 37.1 bits (82), Expect = 0.15
Identities = 18/58 (31%), Positives = 33/58 (56%), Gaps = 4/58 (6%)
Query: 11 VGDKWLVSCLGVLYLCKGLFYRVVPADQRMDTSYAGVFRLHGSYEALKYGSLLDGLAD 68
+GD WL++ + L L + + RVVP +Q +YAG+F ++ +YG ++ + D
Sbjct: 102 LGDCWLLAAIASLTLNEEILARVVPLNQSFQENYAGIFH----FQFWQYGEWVEVVVD 155
>BC011828-1|AAH11828.1| 610|Homo sapiens Unknown (protein for
IMAGE:3833113) protein.
Length = 610
Score = 146 bits (355), Expect = 1e-34
Identities = 128/422 (30%), Positives = 195/422 (46%), Gaps = 42/422 (9%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITE--SIVMPELSDGSALRTLLDTSSVVTAHYFPPV 106
+++G YEAL G+ +G D TGGI E + P + ++ L S++ +
Sbjct: 187 KINGCYEALSGGATTEGFEDFTGGIAEWYELKKPPPNLFKIIQKALQKGSLLGCS----I 242
Query: 107 TIISVFFLSLPTGIRLVKIRLRRSVINIFQVDTTNEPVYLIRLRRPLGHGETPISHIVLD 166
I S T +LVK SV +V++ LIR+R P G E +
Sbjct: 243 DITSAADSEAITFQKLVKGHAY-SVTGAEEVESNGSLQKLIRIRNPWGEVEWT-GRWNDN 300
Query: 167 TALWKTIPQYERDRLMTASKG--VWMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQKW 224
W TI ER+RL + WM FSDF R + R+E+ +L +T L+ +KW
Sbjct: 301 CPSWNTIDPEERERLTRRHEDGEFWMSFSDFLRHYSRLEICNLTPDT----LTSDTYKKW 356
Query: 225 QMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPD----------TVIISLNQ-HS 273
++ G W+RG +AGGCRNY N F NPQ I L E D T ++ L Q H
Sbjct: 357 KLTKMDGNWRRGSTAGGCRNYPNTFWMNPQYLIKLEEEDEDEEDGESGCTFLVGLIQKHR 416
Query: 274 IMEPKV------IGFSVYKMPKFLTETAN----QMFFKRIKSTINSQ-YTNSRQVSQRCQ 322
+ K+ IGF +Y++P+ L+ N + FF ++ S + N R+V R +
Sbjct: 417 RRQRKMGEDMHTIGFGIYEVPEELSGQTNIHLSKNFFLTNRARERSDTFINLREVLNRFK 476
Query: 323 LESGAYLIMPTTFEPREEAQFTLRIYSNKPLKMKVLDDPPQMTKAALVKAPPGSDSNGFF 382
L G Y+++P+TFEP ++ F +R++S K + +DD + + D +GF
Sbjct: 477 LPPGEYILVPSTFEPNKDGDFCIRVFSEKKADYQAVDDEIEANLEEFDISEDDID-DGF- 534
Query: 383 QYETLFLQLADAHRTIDIFELQELLDACLP--NDYIKSCVSIDTLKHLQLVFKTHAREKM 440
LF QLA I FELQ +L L D SI+T K + + + K+
Sbjct: 535 --RRLFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKL 592
Query: 441 GV 442
G+
Sbjct: 593 GL 594
Score = 37.1 bits (82), Expect = 0.15
Identities = 18/58 (31%), Positives = 33/58 (56%), Gaps = 4/58 (6%)
Query: 11 VGDKWLVSCLGVLYLCKGLFYRVVPADQRMDTSYAGVFRLHGSYEALKYGSLLDGLAD 68
+GD WL++ + L L + + RVVP +Q +YAG+F ++ +YG ++ + D
Sbjct: 102 LGDCWLLAAIASLTLNEEILARVVPLNQSFQENYAGIFH----FQFWQYGEWVEVVVD 155
>BC007686-1|AAH07686.1| 610|Homo sapiens Unknown (protein for
IMAGE:3637421) protein.
Length = 610
Score = 146 bits (355), Expect = 1e-34
Identities = 128/422 (30%), Positives = 195/422 (46%), Gaps = 42/422 (9%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITE--SIVMPELSDGSALRTLLDTSSVVTAHYFPPV 106
+++G YEAL G+ +G D TGGI E + P + ++ L S++ +
Sbjct: 187 KINGCYEALSGGATTEGFEDFTGGIAEWYELKKPPPNLFKIIQKALQKGSLLGCS----I 242
Query: 107 TIISVFFLSLPTGIRLVKIRLRRSVINIFQVDTTNEPVYLIRLRRPLGHGETPISHIVLD 166
I S T +LVK SV +V++ LIR+R P G E +
Sbjct: 243 DITSAADSEAITFQKLVKGHAY-SVTGAEEVESNGSLQKLIRIRNPWGEVEWT-GRWNDN 300
Query: 167 TALWKTIPQYERDRLMTASKG--VWMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQKW 224
W TI ER+RL + WM FSDF R + R+E+ +L +T L+ +KW
Sbjct: 301 CPSWNTIDPEERERLTRRHEDGEFWMSFSDFLRHYSRLEICNLTPDT----LTSDTYKKW 356
Query: 225 QMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPD----------TVIISLNQ-HS 273
++ G W+RG +AGGCRNY N F NPQ I L E D T ++ L Q H
Sbjct: 357 KLTKMDGNWRRGSTAGGCRNYPNTFWMNPQYLIKLEEEDEDEEDGESGCTFLVGLIQKHR 416
Query: 274 IMEPKV------IGFSVYKMPKFLTETAN----QMFFKRIKSTINSQ-YTNSRQVSQRCQ 322
+ K+ IGF +Y++P+ L+ N + FF ++ S + N R+V R +
Sbjct: 417 RRQRKMGEDMHTIGFGIYEVPEELSGQTNIHLSKNFFLTNRARERSDTFINLREVLNRFK 476
Query: 323 LESGAYLIMPTTFEPREEAQFTLRIYSNKPLKMKVLDDPPQMTKAALVKAPPGSDSNGFF 382
L G Y+++P+TFEP ++ F +R++S K + +DD + + D +GF
Sbjct: 477 LPPGEYILVPSTFEPNKDGDFCIRVFSEKKADYQAVDDEIEANLEEFDISEDDID-DGF- 534
Query: 383 QYETLFLQLADAHRTIDIFELQELLDACLP--NDYIKSCVSIDTLKHLQLVFKTHAREKM 440
LF QLA I FELQ +L L D SI+T K + + + K+
Sbjct: 535 --RRLFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKL 592
Query: 441 GV 442
G+
Sbjct: 593 GL 594
Score = 37.1 bits (82), Expect = 0.15
Identities = 18/58 (31%), Positives = 33/58 (56%), Gaps = 4/58 (6%)
Query: 11 VGDKWLVSCLGVLYLCKGLFYRVVPADQRMDTSYAGVFRLHGSYEALKYGSLLDGLAD 68
+GD WL++ + L L + + RVVP +Q +YAG+F ++ +YG ++ + D
Sbjct: 102 LGDCWLLAAIASLTLNEEILARVVPLNQSFQENYAGIFH----FQFWQYGEWVEVVVD 155
>AF127765-1|AAD28254.3| 729|Homo sapiens calpain 3 protein.
Length = 729
Score = 144 bits (350), Expect = 5e-34
Identities = 132/507 (26%), Positives = 233/507 (45%), Gaps = 65/507 (12%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVMPELSDG--SALRTLLDTSSVVTAHYFPPV 106
+LHGSYEALK G+ + + D TGG+ E + + ++ ++ S++
Sbjct: 211 KLHGSYEALKGGNTTEAMEDFTGGVAEFFEIRDAPSDMYKIMKKAIERGSLMGCSID--- 267
Query: 107 TIISVFFLSLPTGIRLVKIRLRRSVINIFQVDTTNEPVYLIRLRRPLGHGETPISHIVLD 166
TII V + LV+ SV + +V E V L+RLR P G E S
Sbjct: 268 TIIPVQY-ETRMACGLVRGHAY-SVTGLDEVPFKGEKVKLVRLRNPWGQVEWNGSWSDRW 325
Query: 167 TALWKTIPQYERDRL---MTASKGVWMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQK 223
W + + E+ RL +T WM + DF F ++E+ +L + +++ + Q
Sbjct: 326 KD-WSFVDKDEKARLQHQVTEDGEFWMSYEDFIYHFTKLEICNLTADALQSD----KLQT 380
Query: 224 WQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPD----------TVIISLNQHS 273
W + +++G W RG SAGGCRN+ + F TNPQ ++ L E D + +++L Q +
Sbjct: 381 WTVSVNEGRWVRGCSAGGCRNFPDTFWTNPQYRLKLLEEDDDPDDSEVICSFLVALMQKN 440
Query: 274 IMEPK-------VIGFSVYKMPKFLTETANQM---FFKRIKSTINSQ-YTNSRQVSQRCQ 322
+ + IGF++Y++PK + + FF S S+ Y N R+VSQR +
Sbjct: 441 RRKDRKLGASLFTIGFAIYEVPKEMHGNKQHLQKDFFLYNASKARSKTYINMREVSQRFR 500
Query: 323 LESGAYLIMPTTFEPREEAQFTLRIYSNKPLKMKVLDDPPQMTKAALVKAPPGSDSNGFF 382
L Y+I+P+T+EP +E +F LR++S K + +++ + + +S
Sbjct: 501 LPPSEYVIVPSTYEPHQEGEFILRVFSEKRNLSEEVENTISVDRPVPQPGSSDQESEEQQ 560
Query: 383 QYETLFLQLADAHRTIDIFELQELLDACLPND--------YIKSCVS----IDT------ 424
Q+ +F Q+A I EL+++L+ + ++SC S +DT
Sbjct: 561 QFRNIFKQIAGDDMEICADELKKVLNTVVNKHKDLKTHGFTLESCRSMIALMDTDGSGKL 620
Query: 425 -----------LKHLQLVFKTHAREKMGVLRVERLRDALKDVGFIVPERVISLLVFRYMR 473
+K Q +FK + ++ G + +R+A+ D GF + ++ ++ RY
Sbjct: 621 NLQEFHHLWNKIKAWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDIITMRYAD 680
Query: 474 KDGMLRFGDFVSAVMHLHRVFVQVYDF 500
K + F F+ + L +F + F
Sbjct: 681 KHMNIDFDSFICCFVRLEGMFRAFHAF 707
Score = 40.3 bits (90), Expect = 0.016
Identities = 19/58 (32%), Positives = 33/58 (56%), Gaps = 4/58 (6%)
Query: 11 VGDKWLVSCLGVLYLCKGLFYRVVPADQRMDTSYAGVFRLHGSYEALKYGSLLDGLAD 68
+GD W ++ + L L + L +RV+P DQ +YAG+F ++ +YG +D + D
Sbjct: 126 LGDCWFLAAIACLTLNQHLLFRVIPHDQSFIENYAGIFH----FQFWRYGEWVDVVID 179
>BC033733-1|AAH33733.1| 702|Homo sapiens calpain 11 protein.
Length = 702
Score = 136 bits (328), Expect = 2e-31
Identities = 140/505 (27%), Positives = 228/505 (45%), Gaps = 73/505 (14%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVM--PELSDGSALRTLLDTSSVVTAHYFPPV 106
+L GSYEAL GS ++GL D TGG+ +S + P + LR ++ SS++ +
Sbjct: 184 KLSGSYEALSGGSTMEGLEDFTGGVAQSFQLQRPPQNLLRLLRKAVERSSLMGCS----I 239
Query: 107 TIISVFFLSLPTGIRLVKIRLRRSVINIFQVDTTNEPVYLIRLRRPLGHGETPISHIVLD 166
+ S L T LV+ SV + V + LIR+R P G E + D
Sbjct: 240 EVTSDSELESMTDKMLVRGHAY-SVTGLQDVHYRGKMETLIRVRNPWGRIEW--NGAWSD 296
Query: 167 TAL-WKTIPQYERDRLM--TASKGVWMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQK 223
+A W+ + + +L+ T WM + DF F +E+ +L +T LS K
Sbjct: 297 SAREWEEVASDIQMQLLHKTEDGEFWMSYQDFLNNFTLLEICNLTPDT----LSGDYKSY 352
Query: 224 WQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPD-------------TVIISLN 270
W ++G W+RG SAGGCRN+ F TNPQ +I L E D T +++L
Sbjct: 353 WHTTFYEGSWRRGSSAGGCRNHPGTFWTNPQFKISLPEGDDPEDDAEGNVVACTCLVALM 412
Query: 271 Q----HSIMEP---KVIGFSVYKMPKFLTETAN-----QMFFKRIKSTINSQYTNSRQVS 318
Q H+ + + IGF +Y +PK + + F K + +TNSR+VS
Sbjct: 413 QKNWRHARQQGAQLQTIGFVLYAVPKEFQNIQDVHLKKEFFTKYQDHGFSEIFTNSREVS 472
Query: 319 QRCQLESGAYLIMPTTFEPREEAQFTLRIYSNKPLKMKVLDDPPQMTKAALVKAPPGSDS 378
+ +L G Y+I+P+TFEP +A F LR+++ K + LD+ + A ++ S+
Sbjct: 473 SQLRLPPGEYIIIPSTFEPHRDADFLLRVFTEKHSESWELDE---VNYAEQLQEEKVSED 529
Query: 379 NGFFQYETLFLQLADAHRTIDIFELQEL-----------------LDAC------LPND- 414
+ + LF +A + I ++ELQ L LDAC + D
Sbjct: 530 DMDQDFLHLFKIVAGEGKEIGVYELQRLLNRMAIKFKSFKTKGFGLDACRCMINLMDKDG 589
Query: 415 -----YIKSCVSIDTLKHLQLVFKTHAREKMGVLRVERLRDALKDVGFIVPERVISLLVF 469
++ + LK +F+ ++ G L +R ++ G + +V+ +LV
Sbjct: 590 SGKLGLLEFKILWKKLKKWMDIFRECDQDHSGTLNSYEMRLVIEKAGIKLNNKVMQVLVA 649
Query: 470 RYMRKDGMLRFGDFVSAVMHLHRVF 494
RY D ++ F F+S + L +F
Sbjct: 650 RYADDDLIIDFDSFISCFLRLKTMF 674
Score = 43.6 bits (98), Expect = 0.002
Identities = 18/38 (47%), Positives = 24/38 (63%)
Query: 11 VGDKWLVSCLGVLYLCKGLFYRVVPADQRMDTSYAGVF 48
+GD WL++ +G L C L YRVVP Q +YAG+F
Sbjct: 99 LGDCWLLAAIGSLTTCPKLLYRVVPRGQSFKKNYAGIF 136
>AL365192-3|CAI20532.2| 739|Homo sapiens calpain 11 protein.
Length = 739
Score = 136 bits (328), Expect = 2e-31
Identities = 140/505 (27%), Positives = 228/505 (45%), Gaps = 73/505 (14%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVM--PELSDGSALRTLLDTSSVVTAHYFPPV 106
+L GSYEAL GS ++GL D TGG+ +S + P + LR ++ SS++ +
Sbjct: 221 KLSGSYEALSGGSTMEGLEDFTGGVAQSFQLQRPPQNLLRLLRKAVERSSLMGCS----I 276
Query: 107 TIISVFFLSLPTGIRLVKIRLRRSVINIFQVDTTNEPVYLIRLRRPLGHGETPISHIVLD 166
+ S L T LV+ SV + V + LIR+R P G E + D
Sbjct: 277 EVTSDSELESMTDKMLVRGHAY-SVTGLQDVHYRGKMETLIRVRNPWGRIEW--NGAWSD 333
Query: 167 TAL-WKTIPQYERDRLM--TASKGVWMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQK 223
+A W+ + + +L+ T WM + DF F +E+ +L +T LS K
Sbjct: 334 SAREWEEVASDIQMQLLHKTEDGEFWMSYQDFLNNFTLLEICNLTPDT----LSGDYKSY 389
Query: 224 WQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPD-------------TVIISLN 270
W ++G W+RG SAGGCRN+ F TNPQ +I L E D T +++L
Sbjct: 390 WHTTFYEGSWRRGSSAGGCRNHPGTFWTNPQFKISLPEGDDPEDDAEGNVVVCTCLVALM 449
Query: 271 Q----HSIMEP---KVIGFSVYKMPKFLTETAN-----QMFFKRIKSTINSQYTNSRQVS 318
Q H+ + + IGF +Y +PK + + F K + +TNSR+VS
Sbjct: 450 QKNWRHARQQGAQLQTIGFVLYAVPKEFQNIQDVHLKKEFFTKYQDHGFSEIFTNSREVS 509
Query: 319 QRCQLESGAYLIMPTTFEPREEAQFTLRIYSNKPLKMKVLDDPPQMTKAALVKAPPGSDS 378
+ +L G Y+I+P+TFEP +A F LR+++ K + LD+ + A ++ S+
Sbjct: 510 SQLRLPPGEYIIIPSTFEPHRDADFLLRVFTEKHSESWELDE---VNYAEQLQEEKVSED 566
Query: 379 NGFFQYETLFLQLADAHRTIDIFELQEL-----------------LDAC------LPND- 414
+ + LF +A + I ++ELQ L LDAC + D
Sbjct: 567 DMDQDFLHLFKIVAGEGKEIGVYELQRLLNRMAIKFKSFKTKGFGLDACRCMINLMDKDG 626
Query: 415 -----YIKSCVSIDTLKHLQLVFKTHAREKMGVLRVERLRDALKDVGFIVPERVISLLVF 469
++ + LK +F+ ++ G L +R ++ G + +V+ +LV
Sbjct: 627 SGKLGLLEFKILWKKLKKWMDIFRECDQDHSGTLNSYEMRLVIEKAGIKLNNKVMQVLVA 686
Query: 470 RYMRKDGMLRFGDFVSAVMHLHRVF 494
RY D ++ F F+S + L +F
Sbjct: 687 RYADDDLIIDFDSFISCFLRLKTMF 711
Score = 43.6 bits (98), Expect = 0.002
Identities = 18/38 (47%), Positives = 24/38 (63%)
Query: 11 VGDKWLVSCLGVLYLCKGLFYRVVPADQRMDTSYAGVF 48
+GD WL++ +G L C L YRVVP Q +YAG+F
Sbjct: 136 LGDCWLLAAIGSLTTCPKLLYRVVPRGQSFKKNYAGIF 173
>AJ242832-1|CAB52137.1| 702|Homo sapiens calpain protein.
Length = 702
Score = 136 bits (328), Expect = 2e-31
Identities = 140/505 (27%), Positives = 228/505 (45%), Gaps = 73/505 (14%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVM--PELSDGSALRTLLDTSSVVTAHYFPPV 106
+L GSYEAL GS ++GL D TGG+ +S + P + LR ++ SS++ +
Sbjct: 184 KLSGSYEALSGGSTMEGLEDFTGGVAQSFQLQRPPQNLLRLLRKAVERSSLMGCS----I 239
Query: 107 TIISVFFLSLPTGIRLVKIRLRRSVINIFQVDTTNEPVYLIRLRRPLGHGETPISHIVLD 166
+ S L T LV+ SV + V + LIR+R P G E + D
Sbjct: 240 EVTSDSELESMTDKMLVRGHAY-SVTGLQDVHYRGKMETLIRVRNPWGRIEW--NGAWSD 296
Query: 167 TAL-WKTIPQYERDRLM--TASKGVWMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQK 223
+A W+ + + +L+ T WM + DF F +E+ +L +T LS K
Sbjct: 297 SAREWEEVASDIQMQLLHKTEDGEFWMSYQDFLNNFTLLEICNLTPDT----LSGDYKSY 352
Query: 224 WQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPD-------------TVIISLN 270
W ++G W+RG SAGGCRN+ F TNPQ +I L E D T +++L
Sbjct: 353 WHTTFYEGSWRRGSSAGGCRNHPGTFWTNPQFKISLPEGDDPEDDAEGNVVVCTCLVALM 412
Query: 271 Q----HSIMEP---KVIGFSVYKMPKFLTETAN-----QMFFKRIKSTINSQYTNSRQVS 318
Q H+ + + IGF +Y +PK + + F K + +TNSR+VS
Sbjct: 413 QKNWRHARQQGAQLQTIGFVLYAVPKEFQNIQDVHLKKEFFTKYQDHGFSEIFTNSREVS 472
Query: 319 QRCQLESGAYLIMPTTFEPREEAQFTLRIYSNKPLKMKVLDDPPQMTKAALVKAPPGSDS 378
+ +L G Y+I+P+TFEP +A F LR+++ K + LD+ + A ++ S+
Sbjct: 473 SQLRLPPGEYIIIPSTFEPHRDADFLLRVFTEKHSESWELDE---VNYAEQLQEEKVSED 529
Query: 379 NGFFQYETLFLQLADAHRTIDIFELQEL-----------------LDAC------LPND- 414
+ + LF +A + I ++ELQ L LDAC + D
Sbjct: 530 DMDQDFLHLFKIVAGEGKEIGVYELQRLLNRMAIKFKSFKTKGFGLDACRCMINLMDKDG 589
Query: 415 -----YIKSCVSIDTLKHLQLVFKTHAREKMGVLRVERLRDALKDVGFIVPERVISLLVF 469
++ + LK +F+ ++ G L +R ++ G + +V+ +LV
Sbjct: 590 SGKLGLLEFKILWKKLKKWMDIFRECDQDHSGTLNSYEMRLVIEKAGIKLNNKVMQVLVA 649
Query: 470 RYMRKDGMLRFGDFVSAVMHLHRVF 494
RY D ++ F F+S + L +F
Sbjct: 650 RYADDDLIIDFDSFISCFLRLKTMF 674
Score = 43.6 bits (98), Expect = 0.002
Identities = 18/38 (47%), Positives = 24/38 (63%)
Query: 11 VGDKWLVSCLGVLYLCKGLFYRVVPADQRMDTSYAGVF 48
+GD WL++ +G L C L YRVVP Q +YAG+F
Sbjct: 99 LGDCWLLAAIGSLTTCPKLLYRVVPRGQSFKKNYAGIF 136
>X85030-1|CAA59403.1| 821|Homo sapiens calpain protein.
Length = 821
Score = 111 bits (267), Expect = 6e-24
Identities = 78/246 (31%), Positives = 127/246 (51%), Gaps = 29/246 (11%)
Query: 130 SVINIFQVDTTNEPVYLIRLRRPLGHGETPISHIVLDTALWKTIPQYERDRL---MTASK 186
SV + +V E V L+RLR P G E S W + + E+ RL +T
Sbjct: 337 SVTGLDEVPFKGEKVKLVRLRNPWGQVEWNGSWSDRWKD-WSFVDKDEKARLQHQVTEDG 395
Query: 187 GVWMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQKWQMKMHQGGWKRGVSAGGCRNYV 246
WM + DF F ++E+ +L + +++ + Q W + +++G W RG SAGGCRN+
Sbjct: 396 EFWMSYEDFIYHFTKLEICNLTADALQSD----KLQTWTVSVNEGRWVRGCSAGGCRNFP 451
Query: 247 NFFHTNPQVQIMLNEPD----------TVIISLNQHSIMEPK-------VIGFSVYKMPK 289
+ F TNPQ ++ L E D + +++L Q + + + IGF++Y++PK
Sbjct: 452 DTFWTNPQYRLKLLEEDDDPDDSEVICSFLVALMQKNRRKDRKLGASLFTIGFAIYEVPK 511
Query: 290 FLTETANQM---FFKRIKSTINSQ-YTNSRQVSQRCQLESGAYLIMPTTFEPREEAQFTL 345
+ + FF S S+ Y N R+VSQR +L Y+I+P+T+EP +E +F L
Sbjct: 512 EMHGNKQHLQKDFFLYNASKARSKTYINMREVSQRFRLPPSEYVIVPSTYEPHQEGEFIL 571
Query: 346 RIYSNK 351
R++S K
Sbjct: 572 RVFSEK 577
Score = 40.3 bits (90), Expect = 0.016
Identities = 19/58 (32%), Positives = 33/58 (56%), Gaps = 4/58 (6%)
Query: 11 VGDKWLVSCLGVLYLCKGLFYRVVPADQRMDTSYAGVFRLHGSYEALKYGSLLDGLAD 68
+GD W ++ + L L + L +RV+P DQ +YAG+F ++ +YG +D + D
Sbjct: 126 LGDCWFLAAIACLTLNQHLLFRVIPHDQSFIENYAGIFH----FQFWRYGEWVDVVID 179
Score = 38.7 bits (86), Expect = 0.048
Identities = 18/76 (23%), Positives = 37/76 (48%)
Query: 425 LKHLQLVFKTHAREKMGVLRVERLRDALKDVGFIVPERVISLLVFRYMRKDGMLRFGDFV 484
+K Q +FK + ++ G + +R+A+ D GF + ++ ++ RY K + F F+
Sbjct: 724 IKAWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDIITMRYADKHMNIDFDSFI 783
Query: 485 SAVMHLHRVFVQVYDF 500
+ L +F + F
Sbjct: 784 CCFVRLEGMFRAFHAF 799
Score = 38.3 bits (85), Expect = 0.064
Identities = 15/27 (55%), Positives = 20/27 (74%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITE 75
+LHGSYEALK G+ + + D TGG+ E
Sbjct: 211 KLHGSYEALKGGNTTEAMEDFTGGVAE 237
>AY902237-1|AAW69391.1| 821|Homo sapiens calpain 3, (p94) protein.
Length = 821
Score = 111 bits (267), Expect = 6e-24
Identities = 78/246 (31%), Positives = 127/246 (51%), Gaps = 29/246 (11%)
Query: 130 SVINIFQVDTTNEPVYLIRLRRPLGHGETPISHIVLDTALWKTIPQYERDRL---MTASK 186
SV + +V E V L+RLR P G E S W + + E+ RL +T
Sbjct: 337 SVTGLDEVPFKGEKVKLVRLRNPWGQVEWNGSWSDRWKD-WSFVDKDEKARLQHQVTEDG 395
Query: 187 GVWMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQKWQMKMHQGGWKRGVSAGGCRNYV 246
WM + DF F ++E+ +L + +++ + Q W + +++G W RG SAGGCRN+
Sbjct: 396 EFWMSYEDFIYHFTKLEICNLTADALQSD----KLQTWTVSVNEGRWVRGCSAGGCRNFP 451
Query: 247 NFFHTNPQVQIMLNEPD----------TVIISLNQHSIMEPK-------VIGFSVYKMPK 289
+ F TNPQ ++ L E D + +++L Q + + + IGF++Y++PK
Sbjct: 452 DTFWTNPQYRLKLLEEDDDPDDSEVICSFLVALMQKNRRKDRKLGASLFTIGFAIYEVPK 511
Query: 290 FLTETANQM---FFKRIKSTINSQ-YTNSRQVSQRCQLESGAYLIMPTTFEPREEAQFTL 345
+ + FF S S+ Y N R+VSQR +L Y+I+P+T+EP +E +F L
Sbjct: 512 EMHGNKQHLQKDFFLYNASKARSKTYINMREVSQRFRLPPSEYVIVPSTYEPHQEGEFIL 571
Query: 346 RIYSNK 351
R++S K
Sbjct: 572 RVFSEK 577
Score = 40.3 bits (90), Expect = 0.016
Identities = 19/58 (32%), Positives = 33/58 (56%), Gaps = 4/58 (6%)
Query: 11 VGDKWLVSCLGVLYLCKGLFYRVVPADQRMDTSYAGVFRLHGSYEALKYGSLLDGLAD 68
+GD W ++ + L L + L +RV+P DQ +YAG+F ++ +YG +D + D
Sbjct: 126 LGDCWFLAAIACLTLNQHLLFRVIPHDQSFIENYAGIFH----FQFWRYGEWVDVVID 179
Score = 38.7 bits (86), Expect = 0.048
Identities = 18/76 (23%), Positives = 37/76 (48%)
Query: 425 LKHLQLVFKTHAREKMGVLRVERLRDALKDVGFIVPERVISLLVFRYMRKDGMLRFGDFV 484
+K Q +FK + ++ G + +R+A+ D GF + ++ ++ RY K + F F+
Sbjct: 724 IKAWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDIITMRYADKHMNIDFDSFI 783
Query: 485 SAVMHLHRVFVQVYDF 500
+ L +F + F
Sbjct: 784 CCFVRLEGMFRAFHAF 799
Score = 38.3 bits (85), Expect = 0.064
Identities = 15/27 (55%), Positives = 20/27 (74%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITE 75
+LHGSYEALK G+ + + D TGG+ E
Sbjct: 211 KLHGSYEALKGGNTTEAMEDFTGGVAE 237
>AF209502-1|AAL40183.1| 821|Homo sapiens calpain protein.
Length = 821
Score = 111 bits (267), Expect = 6e-24
Identities = 78/246 (31%), Positives = 127/246 (51%), Gaps = 29/246 (11%)
Query: 130 SVINIFQVDTTNEPVYLIRLRRPLGHGETPISHIVLDTALWKTIPQYERDRL---MTASK 186
SV + +V E V L+RLR P G E S W + + E+ RL +T
Sbjct: 337 SVTGLDEVPFKGEKVKLVRLRNPWGQVEWNGSWSDRWKD-WSFVDKDEKARLQHQVTEDG 395
Query: 187 GVWMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQKWQMKMHQGGWKRGVSAGGCRNYV 246
WM + DF F ++E+ +L + +++ + Q W + +++G W RG SAGGCRN+
Sbjct: 396 EFWMSYEDFIYHFTKLEICNLTADALQSD----KLQTWTVSVNEGRWVRGCSAGGCRNFP 451
Query: 247 NFFHTNPQVQIMLNEPD----------TVIISLNQHSIMEPK-------VIGFSVYKMPK 289
+ F TNPQ ++ L E D + +++L Q + + + IGF++Y++PK
Sbjct: 452 DTFWTNPQYRLKLLEEDDDPDDSEVICSFLVALMQKNRRKDRKLGASLFTIGFAIYEVPK 511
Query: 290 FLTETANQM---FFKRIKSTINSQ-YTNSRQVSQRCQLESGAYLIMPTTFEPREEAQFTL 345
+ + FF S S+ Y N R+VSQR +L Y+I+P+T+EP +E +F L
Sbjct: 512 EMHGNKQHLQKDFFLYNASKARSKTYINMREVSQRFRLPPSEYVIVPSTYEPHQEGEFIL 571
Query: 346 RIYSNK 351
R++S K
Sbjct: 572 RVFSEK 577
Score = 40.3 bits (90), Expect = 0.016
Identities = 19/58 (32%), Positives = 33/58 (56%), Gaps = 4/58 (6%)
Query: 11 VGDKWLVSCLGVLYLCKGLFYRVVPADQRMDTSYAGVFRLHGSYEALKYGSLLDGLAD 68
+GD W ++ + L L + L +RV+P DQ +YAG+F ++ +YG +D + D
Sbjct: 126 LGDCWFLAAIACLTLNQHLLFRVIPHDQSFIENYAGIFH----FQFWRYGEWVDVVID 179
Score = 38.7 bits (86), Expect = 0.048
Identities = 18/76 (23%), Positives = 37/76 (48%)
Query: 425 LKHLQLVFKTHAREKMGVLRVERLRDALKDVGFIVPERVISLLVFRYMRKDGMLRFGDFV 484
+K Q +FK + ++ G + +R+A+ D GF + ++ ++ RY K + F F+
Sbjct: 724 IKAWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDIITMRYADKHMNIDFDSFI 783
Query: 485 SAVMHLHRVFVQVYDF 500
+ L +F + F
Sbjct: 784 CCFVRLEGMFRAFHAF 799
Score = 38.3 bits (85), Expect = 0.064
Identities = 15/27 (55%), Positives = 20/27 (74%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITE 75
+LHGSYEALK G+ + + D TGG+ E
Sbjct: 211 KLHGSYEALKGGNTTEAMEDFTGGVAE 237
>AF127764-1|AAD28253.1| 815|Homo sapiens calpain 3 protein.
Length = 815
Score = 111 bits (267), Expect = 6e-24
Identities = 78/246 (31%), Positives = 127/246 (51%), Gaps = 29/246 (11%)
Query: 130 SVINIFQVDTTNEPVYLIRLRRPLGHGETPISHIVLDTALWKTIPQYERDRL---MTASK 186
SV + +V E V L+RLR P G E S W + + E+ RL +T
Sbjct: 337 SVTGLDEVPFKGEKVKLVRLRNPWGQVEWNGSWSDRWKD-WSFVDKDEKARLQHQVTEDG 395
Query: 187 GVWMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQKWQMKMHQGGWKRGVSAGGCRNYV 246
WM + DF F ++E+ +L + +++ + Q W + +++G W RG SAGGCRN+
Sbjct: 396 EFWMSYEDFIYHFTKLEICNLTADALQSD----KLQTWTVSVNEGRWVRGCSAGGCRNFP 451
Query: 247 NFFHTNPQVQIMLNEPD----------TVIISLNQHSIMEPK-------VIGFSVYKMPK 289
+ F TNPQ ++ L E D + +++L Q + + + IGF++Y++PK
Sbjct: 452 DTFWTNPQYRLKLLEEDDDPDDSEVICSFLVALMQKNRRKDRKLGASLFTIGFAIYEVPK 511
Query: 290 FLTETANQM---FFKRIKSTINSQ-YTNSRQVSQRCQLESGAYLIMPTTFEPREEAQFTL 345
+ + FF S S+ Y N R+VSQR +L Y+I+P+T+EP +E +F L
Sbjct: 512 EMHGNKQHLQKDFFLYNASKARSKTYINMREVSQRFRLPPSEYVIVPSTYEPHQEGEFIL 571
Query: 346 RIYSNK 351
R++S K
Sbjct: 572 RVFSEK 577
Score = 40.3 bits (90), Expect = 0.016
Identities = 19/58 (32%), Positives = 33/58 (56%), Gaps = 4/58 (6%)
Query: 11 VGDKWLVSCLGVLYLCKGLFYRVVPADQRMDTSYAGVFRLHGSYEALKYGSLLDGLAD 68
+GD W ++ + L L + L +RV+P DQ +YAG+F ++ +YG +D + D
Sbjct: 126 LGDCWFLAAIACLTLNQHLLFRVIPHDQSFIENYAGIFH----FQFWRYGEWVDVVID 179
Score = 38.7 bits (86), Expect = 0.048
Identities = 18/76 (23%), Positives = 37/76 (48%)
Query: 425 LKHLQLVFKTHAREKMGVLRVERLRDALKDVGFIVPERVISLLVFRYMRKDGMLRFGDFV 484
+K Q +FK + ++ G + +R+A+ D GF + ++ ++ RY K + F F+
Sbjct: 718 IKAWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDIITMRYADKHMNIDFDSFI 777
Query: 485 SAVMHLHRVFVQVYDF 500
+ L +F + F
Sbjct: 778 CCFVRLEGMFRAFHAF 793
Score = 38.3 bits (85), Expect = 0.064
Identities = 15/27 (55%), Positives = 20/27 (74%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITE 75
+LHGSYEALK G+ + + D TGG+ E
Sbjct: 211 KLHGSYEALKGGNTTEAMEDFTGGVAE 237
>AB117940-1|BAD16649.1| 728|Homo sapiens hUp84 protein.
Length = 728
Score = 111 bits (267), Expect = 6e-24
Identities = 78/246 (31%), Positives = 127/246 (51%), Gaps = 29/246 (11%)
Query: 130 SVINIFQVDTTNEPVYLIRLRRPLGHGETPISHIVLDTALWKTIPQYERDRL---MTASK 186
SV + +V E V L+RLR P G E S W + + E+ RL +T
Sbjct: 250 SVTELDEVPFKGEKVKLVRLRNPWGQVEWNGSWSDRWKD-WSFVDKDEKARLQHQVTEDG 308
Query: 187 GVWMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQKWQMKMHQGGWKRGVSAGGCRNYV 246
WM + DF F ++E+ +L + +++ + Q W + +++G W RG SAGGCRN+
Sbjct: 309 EFWMSYEDFIYHFTKLEICNLTADALQSD----KLQTWTVSVNEGRWVRGCSAGGCRNFP 364
Query: 247 NFFHTNPQVQIMLNEPD----------TVIISLNQHSIMEPK-------VIGFSVYKMPK 289
+ F TNPQ ++ L E D + +++L Q + + + IGF++Y++PK
Sbjct: 365 DTFWTNPQYRLKLLEEDDDPDDSEVICSFLVALMQKNRRKDRKLGASLFTIGFAIYEVPK 424
Query: 290 FLTETANQM---FFKRIKSTINSQ-YTNSRQVSQRCQLESGAYLIMPTTFEPREEAQFTL 345
+ + FF S S+ Y N R+VSQR +L Y+I+P+T+EP +E +F L
Sbjct: 425 EMHGNKQHLQKDFFLYNASKARSKTYINMREVSQRFRLPPSEYVIVPSTYEPHQEGEFIL 484
Query: 346 RIYSNK 351
R++S K
Sbjct: 485 RVFSEK 490
Score = 40.3 bits (90), Expect = 0.016
Identities = 19/58 (32%), Positives = 33/58 (56%), Gaps = 4/58 (6%)
Query: 11 VGDKWLVSCLGVLYLCKGLFYRVVPADQRMDTSYAGVFRLHGSYEALKYGSLLDGLAD 68
+GD W ++ + L L + L +RV+P DQ +YAG+F ++ +YG +D + D
Sbjct: 39 LGDCWFLAAIACLTLNQHLLFRVIPHDQSFIENYAGIFH----FQFWRYGEWVDVVID 92
Score = 38.7 bits (86), Expect = 0.048
Identities = 18/76 (23%), Positives = 37/76 (48%)
Query: 425 LKHLQLVFKTHAREKMGVLRVERLRDALKDVGFIVPERVISLLVFRYMRKDGMLRFGDFV 484
+K Q +FK + ++ G + +R+A+ D GF + ++ ++ RY K + F F+
Sbjct: 631 IKAWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDIITMRYADKHMNIDFDSFI 690
Query: 485 SAVMHLHRVFVQVYDF 500
+ L +F + F
Sbjct: 691 CCFVRLEGMFRAFHAF 706
Score = 38.3 bits (85), Expect = 0.064
Identities = 15/27 (55%), Positives = 20/27 (74%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITE 75
+LHGSYEALK G+ + + D TGG+ E
Sbjct: 124 KLHGSYEALKGGNTTEAMEDFTGGVAE 150
>CR628412-1|CAM28354.1| 437|Homo sapiens calpain 8 (nCL-2) protein.
Length = 437
Score = 99 bits (238), Expect = 2e-20
Identities = 73/219 (33%), Positives = 104/219 (47%), Gaps = 14/219 (6%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITE--SIVMPELSDGSALRTLLDTSSVVTAHYFPPV 106
+L+G YEAL GS ++G D TGGI+E + P + +R L S++ +
Sbjct: 187 KLNGCYEALAGGSTVEGFEDFTGGISEFYDLKKPPANLYQIIRKALCAGSLLGCS----I 242
Query: 107 TIISVFFLSLPTGIRLVKIRLRRSVINIFQVDTTNEPVYLIRLRRPLGHGETPISHIVLD 166
+ S T +LVK SV + +V+ P LIRLR P G E + D
Sbjct: 243 DVSSAAEAEAITSQKLVKSHAY-SVTGVEEVNFQGHPEKLIRLRNPWGEVEWSGAWSD-D 300
Query: 167 TALWKTIPQYERDRL--MTASKGVWMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQKW 224
W I ++ L WM SDF R F R+E+ +L ++ LS E KW
Sbjct: 301 APEWNHIDPRRKEELDKKVEDGEFWMSLSDFVRQFSRLEICNLSPDS----LSSEEVHKW 356
Query: 225 QMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPD 263
+ + G W RG +AGGC+NY + TNPQ +I L+E D
Sbjct: 357 NLVLFNGHWTRGSTAGGCQNYPATYWTNPQFKIRLDEVD 395
Score = 42.7 bits (96), Expect = 0.003
Identities = 21/58 (36%), Positives = 34/58 (58%), Gaps = 4/58 (6%)
Query: 11 VGDKWLVSCLGVLYLCKGLFYRVVPADQRMDTSYAGVFRLHGSYEALKYGSLLDGLAD 68
+GD WL++ + L L + L YRVVP DQ +YAG+F ++ +YG ++ + D
Sbjct: 102 LGDCWLLAAIASLTLNEELLYRVVPRDQDFQENYAGIFH----FQFWQYGEWVEVVID 155
>Y10552-1|CAA71584.1| 634|Homo sapiens CAPN5 protein protein.
Length = 634
Score = 88.2 bits (209), Expect = 6e-17
Identities = 97/362 (26%), Positives = 153/362 (42%), Gaps = 52/362 (14%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVMPE---LSDGSALRTLLDTSSVVTAH---Y 102
+L G Y+AL G+ D L D TGG++E I + E +D + L + V +
Sbjct: 169 KLAGCYQALDGGNTADALVDFTGGVSEPIDLTEGDFANDETKRNQLFERMLKVHSRGGLI 228
Query: 103 FPPVTIISVFFLSLPTGIRLVK-----------IRLRRSVINIFQVDTTNEPVYLIRLRR 151
+ ++ + LVK +RL ++ F+ +E + +IRLR
Sbjct: 229 SASIKAVTAADMEARLACGLVKGHAYAVTDVRKVRLGHGLLAFFK----SEKLDMIRLRN 284
Query: 152 PLGHGETPISHIVLDTAL-WKTIPQYERDRLMTASKG---VWMLFSDFQRLFPRIEMVHL 207
P G E + DT+ W+ + + ER+++ + WM F D R F I +
Sbjct: 285 PWGEREW--NGPWSDTSEEWQKVSKSEREKMGVTVQDDGEFWMTFEDVCRYFTDIIKCRV 342
Query: 208 DTETSRAELSLSEKQKWQMKMHQGGWK-----RGVSAGGCRNYVNFFHTNPQVQIMLNEP 262
TS LS + W+ G W R GGC N+ + F NPQ + +P
Sbjct: 343 -INTSH----LSIHKTWEEARLHGAWTLHEDPRQNRGGGCINHKDTFFQNPQYIFEVKKP 397
Query: 263 -DTVIISLNQHSIMEPK--------VIGFSVYKMPKFLTETANQMFFKRIKSTINSQYTN 313
D V+I + Q + IGF +YK+ + + + K S Y N
Sbjct: 398 EDEVLICIQQRPKRSTRREGKGENLAIGFDIYKVEENRQYRMHSLQHKAASSI----YIN 453
Query: 314 SRQVSQRCQLESGAYLIMPTTFEPREEAQFTLRIYSNKPLKMKV--LDDPPQMTKAALVK 371
SR V R G Y+I+PTTFEP +F LR++++ P + LD+PP ++L
Sbjct: 454 SRSVFLRTDQPEGRYVIIPTTFEPGHTGEFLLRVFTDVPSNCRELRLDEPPHTCWSSLCG 513
Query: 372 AP 373
P
Sbjct: 514 YP 515
>BC018123-1|AAH18123.1| 640|Homo sapiens calpain 5 protein.
Length = 640
Score = 88.2 bits (209), Expect = 6e-17
Identities = 97/362 (26%), Positives = 153/362 (42%), Gaps = 52/362 (14%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVMPE---LSDGSALRTLLDTSSVVTAH---Y 102
+L G Y+AL G+ D L D TGG++E I + E +D + L + V +
Sbjct: 169 KLAGCYQALDGGNTADALVDFTGGVSEPIDLTEGDFANDETKRNQLFERMLKVHSRGGLI 228
Query: 103 FPPVTIISVFFLSLPTGIRLVK-----------IRLRRSVINIFQVDTTNEPVYLIRLRR 151
+ ++ + LVK +RL ++ F+ +E + +IRLR
Sbjct: 229 SASIKAVTAADMEARLACGLVKGHAYAVTDVRKVRLGHGLLAFFK----SEKLDMIRLRN 284
Query: 152 PLGHGETPISHIVLDTAL-WKTIPQYERDRLMTASKG---VWMLFSDFQRLFPRIEMVHL 207
P G E + DT+ W+ + + ER+++ + WM F D R F I +
Sbjct: 285 PWGEREW--NGPWSDTSEEWQKVSKSEREKMGVTVQDDGEFWMTFEDVCRYFTDIIKCRV 342
Query: 208 DTETSRAELSLSEKQKWQMKMHQGGWK-----RGVSAGGCRNYVNFFHTNPQVQIMLNEP 262
TS LS + W+ G W R GGC N+ + F NPQ + +P
Sbjct: 343 -INTSH----LSIHKTWEEARLHGAWTLHEDPRQNRGGGCINHKDTFFQNPQYIFEVKKP 397
Query: 263 -DTVIISLNQHSIMEPK--------VIGFSVYKMPKFLTETANQMFFKRIKSTINSQYTN 313
D V+I + Q + IGF +YK+ + + + K S Y N
Sbjct: 398 EDEVLICIQQRPKRSTRREGKGENLAIGFDIYKVEENRQYRMHSLQHKAASSI----YIN 453
Query: 314 SRQVSQRCQLESGAYLIMPTTFEPREEAQFTLRIYSNKPLKMKV--LDDPPQMTKAALVK 371
SR V R G Y+I+PTTFEP +F LR++++ P + LD+PP ++L
Sbjct: 454 SRSVFLRTDQPEGRYVIIPTTFEPGHTGEFLLRVFTDVPSNCRELRLDEPPHTCWSSLCG 513
Query: 372 AP 373
P
Sbjct: 514 YP 515
>AB209087-1|BAD92324.1| 678|Homo sapiens Hypothetical protein
FLJ46245 variant protein.
Length = 678
Score = 87.8 bits (208), Expect = 8e-17
Identities = 97/362 (26%), Positives = 153/362 (42%), Gaps = 52/362 (14%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVMPE---LSDGSALRTLLDTSSVVTAH---Y 102
+L G Y+AL G+ D L D TGG++E I + E +D + L + V +
Sbjct: 207 KLAGCYQALDGGNTADALVDFTGGVSEPIDLTEGDFANDETKRNQLFERMLKVHSRGGLI 266
Query: 103 FPPVTIISVFFLSLPTGIRLVK-----------IRLRRSVINIFQVDTTNEPVYLIRLRR 151
+ ++ + LVK +RL ++ F+ +E + +IRLR
Sbjct: 267 SASIKAVTAADMEARLACGLVKGHAYAVTDVRKVRLGHGLLAFFK----SEKLDMIRLRN 322
Query: 152 PLGHGETPISHIVLDTAL-WKTIPQYERDRLMTASKG---VWMLFSDFQRLFPRIEMVHL 207
P G E + DT+ W+ + + ER+++ + WM F D R F I +
Sbjct: 323 PWGEREW--NGPWSDTSEEWQKVSKSEREKMGVTVQDDGEFWMTFEDVCRYFTDIIKCRV 380
Query: 208 DTETSRAELSLSEKQKWQMKMHQGGWK-----RGVSAGGCRNYVNFFHTNPQVQIMLNEP 262
TS LS + W+ G W R GGC N+ + F NPQ + +P
Sbjct: 381 -INTSH----LSIHKTWEEARLHGAWTLHEDPRQNRGGGCINHKDTFFQNPQYIFEVKKP 435
Query: 263 -DTVIISLNQHSIMEPK--------VIGFSVYKMPKFLTETANQMFFKRIKSTINSQYTN 313
D V+I + Q + IGF +YK+ + + + K S Y N
Sbjct: 436 EDEVLICIQQRPKRSTRREGKGENLAIGFDIYKVEENRQYRMHSLQHK----AAGSIYIN 491
Query: 314 SRQVSQRCQLESGAYLIMPTTFEPREEAQFTLRIYSNKPLKMKV--LDDPPQMTKAALVK 371
SR V R G Y+I+PTTFEP +F LR++++ P + LD+PP ++L
Sbjct: 492 SRSVFLRTDQPEGRYVIIPTTFEPGHTGEFLLRVFTDVPSNCRELRLDEPPHTCWSSLCG 551
Query: 372 AP 373
P
Sbjct: 552 YP 553
>U94346-1|AAC51869.1| 639|Homo sapiens calpain-like protease
protein.
Length = 639
Score = 87.0 bits (206), Expect = 1e-16
Identities = 97/362 (26%), Positives = 152/362 (41%), Gaps = 52/362 (14%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVMPE---LSDGSALRTLLDTSSVVTAH---Y 102
+L G Y+AL G+ D L D TGG++E I + E +D + L + V +
Sbjct: 168 KLAGCYQALDGGNTADALVDFTGGVSEPIDLTEGDFANDETKRNQLFERMLKVHSRGGLI 227
Query: 103 FPPVTIISVFFLSLPTGIRLVK-----------IRLRRSVINIFQVDTTNEPVYLIRLRR 151
+ ++ + LVK +RL ++ F+ +E + +IRLR
Sbjct: 228 SASIKAVTAADMEARLACGLVKGHAYAVTDVRKVRLGHGLLAFFK----SEKLDMIRLRN 283
Query: 152 PLGHGETPISHIVLDTAL-WKTIPQYERDRLMTASKG---VWMLFSDFQRLFPRIEMVHL 207
P G E + DT+ W+ + + ER+++ + WM F D R F I +
Sbjct: 284 PWGEREW--NGPWSDTSEEWQKVSKSEREKMGVTVQDDGEFWMTFEDVCRYFTDIIKCRV 341
Query: 208 DTETSRAELSLSEKQKWQMKMHQGGWK-----RGVSAGGCRNYVNFFHTNPQVQIMLNEP 262
TS LS + W+ G W R GGC N+ + F NPQ + +P
Sbjct: 342 -INTSH----LSIHKTWEEARLHGAWTLHEDPRQNRGGGCINHKDTFFQNPQYIFEVKKP 396
Query: 263 -DTVIISLNQHSIMEPK--------VIGFSVYKMPKFLTETANQMFFKRIKSTINSQYTN 313
D V+I + Q + IGF +YK+ + + + K S Y N
Sbjct: 397 EDEVLICIQQRPKRSTRREGKGENLAIGFDIYKVEENRQYRMHSLQHKAASSI----YIN 452
Query: 314 SRQVSQRCQLESGAYLIMPTTFEPREEAQFTLRIYSNKPLKMKV--LDDPPQMTKAALVK 371
SR V R G Y+I+PTTFEP +F LR++++ P + LD PP ++L
Sbjct: 453 SRSVFLRTDQPEGRYVIIPTTFEPGHTGEFLLRVFTDVPSNCRELRLDKPPHTCWSSLCG 512
Query: 372 AP 373
P
Sbjct: 513 YP 514
>AK128124-1|BAC87282.1| 680|Homo sapiens protein ( Homo sapiens
cDNA FLJ46245 fis, clone TESTI4020596, highly similar
to Homo sapiens calpain 5 (CAPN5). ).
Length = 680
Score = 86.2 bits (204), Expect = 2e-16
Identities = 96/362 (26%), Positives = 152/362 (41%), Gaps = 52/362 (14%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVMPE---LSDGSALRTLLDTSSVVTAH---Y 102
+L G Y+AL G+ D L D GG++E I + E +D + L + V +
Sbjct: 209 KLAGCYQALDGGNTADALVDFAGGVSEPIDLTEGDFANDETKRNQLFERMLKVHSRGGLI 268
Query: 103 FPPVTIISVFFLSLPTGIRLVK-----------IRLRRSVINIFQVDTTNEPVYLIRLRR 151
+ ++ + LVK +RL ++ F+ +E + +IRLR
Sbjct: 269 SASIKAVTAADMEARLACGLVKGHAYAVTDVRKVRLGHGLLAFFK----SEKMDMIRLRN 324
Query: 152 PLGHGETPISHIVLDTAL-WKTIPQYERDRLMTASKG---VWMLFSDFQRLFPRIEMVHL 207
P G E + DT+ W+ + + ER+++ + WM F D R F I +
Sbjct: 325 PWGEREW--NGPWSDTSEEWQKVSKSEREKMGVTVQDDGEFWMTFEDVCRYFTDIIKCRV 382
Query: 208 DTETSRAELSLSEKQKWQMKMHQGGWK-----RGVSAGGCRNYVNFFHTNPQVQIMLNEP 262
TS LS + W+ G W R GGC N+ + F NPQ + +P
Sbjct: 383 -INTSH----LSIHKTWEEARLHGAWTLHEDPRQNRGGGCINHKDTFFQNPQYIFEVKKP 437
Query: 263 -DTVIISLNQHSIMEPK--------VIGFSVYKMPKFLTETANQMFFKRIKSTINSQYTN 313
D V+I + Q + IGF +YK+ + + + K S Y N
Sbjct: 438 EDEVLICIQQRPKRSTRREGKGENLAIGFDIYKVEENRQYRMHSLQHKAASSI----YIN 493
Query: 314 SRQVSQRCQLESGAYLIMPTTFEPREEAQFTLRIYSNKPLKMKV--LDDPPQMTKAALVK 371
SR V R G Y+I+PTTFEP +F LR++++ P + LD+PP ++L
Sbjct: 494 SRSVFLRTDQPEGRYVIIPTTFEPGHTGEFLLRVFTDVPSNCRELRLDEPPHTCWSSLCG 553
Query: 372 AP 373
P
Sbjct: 554 YP 555
>CR628412-2|CAM28355.1| 381|Homo sapiens calpain 8 (nCL-2) protein.
Length = 381
Score = 85.8 bits (203), Expect = 3e-16
Identities = 65/201 (32%), Positives = 93/201 (46%), Gaps = 14/201 (6%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITE--SIVMPELSDGSALRTLLDTSSVVTAHYFPPV 106
+L+G YEAL GS ++G D TGGI+E + P + +R L S++ +
Sbjct: 187 KLNGCYEALAGGSTVEGFEDFTGGISEFYDLKKPPANLYQIIRKALCAGSLLGCS----I 242
Query: 107 TIISVFFLSLPTGIRLVKIRLRRSVINIFQVDTTNEPVYLIRLRRPLGHGETPISHIVLD 166
+ S T +LVK SV + +V+ P LIRLR P G E + D
Sbjct: 243 DVSSAAEAEAITSQKLVKSHAY-SVTGVEEVNFQGHPEKLIRLRNPWGEVEWSGAWSD-D 300
Query: 167 TALWKTIPQYERDRL--MTASKGVWMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQKW 224
W I ++ L WM SDF R F R+E+ +L ++ LS E KW
Sbjct: 301 APEWNHIDPRRKEELDKKVEDGEFWMSLSDFVRQFSRLEICNLSPDS----LSSEEVHKW 356
Query: 225 QMKMHQGGWKRGVSAGGCRNY 245
+ + G W RG +AGGC+NY
Sbjct: 357 NLVLFNGHWTRGSTAGGCQNY 377
Score = 42.7 bits (96), Expect = 0.003
Identities = 21/58 (36%), Positives = 34/58 (58%), Gaps = 4/58 (6%)
Query: 11 VGDKWLVSCLGVLYLCKGLFYRVVPADQRMDTSYAGVFRLHGSYEALKYGSLLDGLAD 68
+GD WL++ + L L + L YRVVP DQ +YAG+F ++ +YG ++ + D
Sbjct: 102 LGDCWLLAAIASLTLNEELLYRVVPRDQDFQENYAGIFH----FQFWQYGEWVEVVID 155
>AK127398-1|BAC86959.1| 719|Homo sapiens protein ( Homo sapiens
cDNA FLJ45489 fis, clone BRTHA2005448, highly similar
to Mus musculus calpain 12 (Capn12). ).
Length = 719
Score = 73.3 bits (172), Expect = 2e-12
Identities = 69/219 (31%), Positives = 96/219 (43%), Gaps = 16/219 (7%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVMPELSDG--SALRTLLDTSSVVTAHYFPPV 106
+LHGSYE ++ G + + D TGG+ E + + + S G SALR L S+V A
Sbjct: 187 KLHGSYEVMRGGHMNEAFVDFTGGVGEVLYLRQNSMGLFSALRHALAKESLVGA------ 240
Query: 107 TIISVFFLSLPTGIRLVKIRLRRSVINIFQVDTTNEPVYLIRLRRPLGHGETPISHIVLD 166
T +S T LVK S+ +V V L+RLR P G E +
Sbjct: 241 TALSDRG-EYRTEEGLVKGHAY-SITGTHKVFLGFTKVRLLRLRNPWGCVEWTGAWSD-S 297
Query: 167 TALWKTIPQYERDRLMTASKG--VWMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQKW 224
W T+P RD L+ + WM DF F +++ L E E W
Sbjct: 298 CPRWDTLPTECRDALLVKKEDGEFWMELRDFLLHFDTVQICSLSPEVLGPS---PEGGGW 354
Query: 225 QMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPD 263
+ QG W RG ++GG + F TNPQ ++ L EPD
Sbjct: 355 HVHTFQGRWVRGFNSGGSQPNAETFWTNPQFRLTLLEPD 393
Score = 54.0 bits (124), Expect = 1e-06
Identities = 65/250 (26%), Positives = 104/250 (41%), Gaps = 41/250 (16%)
Query: 280 IGFSVYKMPKFLT----ETANQMFFKRIKSTINSQYTNSRQVSQRCQLESGAYLIMPTTF 335
+GF V+++P+ L + R+ S + R V++RC L G YL++P+T
Sbjct: 448 VGFHVFQIPEELLGLWDSPRSHALLPRLLRADRSPLSARRDVTRRCCLRPGHYLVVPSTA 507
Query: 336 EPREEAQFTLRIYSNKPLKMKVLDDPPQMTKAALVKAPPGSDSNGFFQYETLFLQLADAH 395
+EA FTLR++S + +DD +A +++ G E LF +LA
Sbjct: 508 HAGDEADFTLRVFSERRHTAVEIDD----VISADLQSLQGPYLPLELGLEQLFQELAGEE 563
Query: 396 RTIDIFELQELLDACL---------PNDY-IKSCVSI---------DTLKHLQ------- 429
++ +LQ LL L P + +++C + L H Q
Sbjct: 564 EELNASQLQALLSIALEPARAHTSTPREIGLRTCEQLLQCFGHGQSLALHHFQQLWGYLL 623
Query: 430 ---LVFKTHAREKMGVLRVERLRDALKDVGFIVPERVISLLVFRYMRKDGMLR--FGDFV 484
+F + G + LR AL GF + ++ L RY +D LR F FV
Sbjct: 624 EWQAIFNKFDEDTSGTMNSYELRLALNAAGFHLNNQLTQTLTSRY--RDSRLRVDFERFV 681
Query: 485 SAVMHLHRVF 494
S V HL +F
Sbjct: 682 SCVAHLTCIF 691
Score = 31.9 bits (69), Expect = 5.5
Identities = 18/59 (30%), Positives = 29/59 (49%), Gaps = 4/59 (6%)
Query: 10 TVGDKWLVSCLGVLYLCKGLFYRVVPADQRMDTSYAGVFRLHGSYEALKYGSLLDGLAD 68
++G+ W ++ L L L RVVP Q YAGVF ++ ++G +D + D
Sbjct: 101 SLGNCWFLAAAASLTLYPRLLRRVVPPGQDFQHGYAGVFH----FQLWQFGRWMDVVVD 155
>AB117941-1|BAD16650.1| 426|Homo sapiens hUp49 protein.
Length = 426
Score = 72.9 bits (171), Expect = 2e-12
Identities = 46/137 (33%), Positives = 71/137 (51%), Gaps = 8/137 (5%)
Query: 130 SVINIFQVDTTNEPVYLIRLRRPLGHGETPISHIVLDTALWKTIPQYERDRL---MTASK 186
SV + +V E V L+RLR P G E S W + + E+ RL +T
Sbjct: 250 SVTELDEVPFKGEKVKLVRLRNPWGQVEWNGSWSDRWKD-WSFVDKDEKARLQHQVTEDG 308
Query: 187 GVWMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQKWQMKMHQGGWKRGVSAGGCRNYV 246
WM + DF F ++E+ +L + +++ + Q W + +++G W RG SAGGCRN+
Sbjct: 309 EFWMSYEDFIYHFTKLEICNLTADALQSD----KLQTWTVSVNEGRWVRGCSAGGCRNFP 364
Query: 247 NFFHTNPQVQIMLNEPD 263
+ F TNPQ ++ L E D
Sbjct: 365 DTFWTNPQYRLKLLEED 381
Score = 40.3 bits (90), Expect = 0.016
Identities = 19/58 (32%), Positives = 33/58 (56%), Gaps = 4/58 (6%)
Query: 11 VGDKWLVSCLGVLYLCKGLFYRVVPADQRMDTSYAGVFRLHGSYEALKYGSLLDGLAD 68
+GD W ++ + L L + L +RV+P DQ +YAG+F ++ +YG +D + D
Sbjct: 39 LGDCWFLAAIACLTLNQHLLFRVIPHDQSFIENYAGIFH----FQFWRYGEWVDVVID 92
Score = 38.3 bits (85), Expect = 0.064
Identities = 15/27 (55%), Positives = 20/27 (74%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITE 75
+LHGSYEALK G+ + + D TGG+ E
Sbjct: 124 KLHGSYEALKGGNTTEAMEDFTGGVAE 150
>BC000730-1|AAH00730.1| 641|Homo sapiens calpain 6 protein.
Length = 641
Score = 69.3 bits (162), Expect = 3e-11
Identities = 75/268 (27%), Positives = 120/268 (44%), Gaps = 31/268 (11%)
Query: 124 KIRLRRSVINIFQVDTTNEPVYLIRLRRPLGHGET--PISHIVLDTALWKTIPQYERDRL 181
KIRL ++ +F E VY++RLR PLG E P S I + W+ + +R L
Sbjct: 261 KIRLGERLVEVFSA----EKVYMVRLRNPLGRQEWSGPWSEISEE---WQQLTASDRKNL 313
Query: 182 ---MTASKGVWMLFSDFQRLFPRIEMVHLDTET--SRAELSLSEKQKWQMKMHQGGWKRG 236
M+ WM DF R F ++ + R EL S W + R
Sbjct: 314 GLVMSDDGEFWMSLEDFCRNFHKLNVCRNVNNPIFGRKELE-SVLGCWTVD-DDPLMNR- 370
Query: 237 VSAGGCRNYVNFFHTNPQVQIMLNEPD-TVIISLNQHSIMEPK--------VIGFSVYKM 287
+GGC N + F NPQ + E VI+SL Q + + +IGF ++K+
Sbjct: 371 --SGGCYNNRDTFLQNPQYIFTVPEDGHKVIMSLQQKDLRTYRRMGRPDNYIIGFELFKV 428
Query: 288 PKFLTETANQMFFKRIKSTINSQYTNSRQVSQRCQLESGAYLIMPTTFEPREEAQFTLRI 347
+ ++ + T S Y ++R V L+ G Y+++PT F+ ++F LRI
Sbjct: 429 EMNRKFRLHHLYIQERAGT--STYIDTRTVFLSKYLKKGNYVLVPTMFQHGRTSEFLLRI 486
Query: 348 YSNKPLKMKVLD-DPPQMTKAALVKAPP 374
+S P++++ L D P+M+ L + P
Sbjct: 487 FSEVPVQLRELTLDMPKMSCWNLARGYP 514
>AY800242-1|AAV41896.1| 641|Homo sapiens calpain 6 protein.
Length = 641
Score = 69.3 bits (162), Expect = 3e-11
Identities = 75/268 (27%), Positives = 120/268 (44%), Gaps = 31/268 (11%)
Query: 124 KIRLRRSVINIFQVDTTNEPVYLIRLRRPLGHGET--PISHIVLDTALWKTIPQYERDRL 181
KIRL ++ +F E VY++RLR PLG E P S I + W+ + +R L
Sbjct: 261 KIRLGERLVEVFSA----EKVYMVRLRNPLGRQEWSGPWSEISEE---WQQLTASDRKNL 313
Query: 182 ---MTASKGVWMLFSDFQRLFPRIEMVHLDTET--SRAELSLSEKQKWQMKMHQGGWKRG 236
M+ WM DF R F ++ + R EL S W + R
Sbjct: 314 GLVMSDDGEFWMSLEDFCRNFHKLNVCRNVNNPIFGRKELE-SVLGCWTVD-DDPLMNR- 370
Query: 237 VSAGGCRNYVNFFHTNPQVQIMLNEPD-TVIISLNQHSIMEPK--------VIGFSVYKM 287
+GGC N + F NPQ + E VI+SL Q + + +IGF ++K+
Sbjct: 371 --SGGCYNNRDTFLQNPQYIFTVPEDGHKVIMSLQQKDLRTYRRMGRPDNYIIGFELFKV 428
Query: 288 PKFLTETANQMFFKRIKSTINSQYTNSRQVSQRCQLESGAYLIMPTTFEPREEAQFTLRI 347
+ ++ + T S Y ++R V L+ G Y+++PT F+ ++F LRI
Sbjct: 429 EMNRKFRLHHLYIQERAGT--STYIDTRTVFLSKYLKKGNYVLVPTMFQHGRTSEFLLRI 486
Query: 348 YSNKPLKMKVLD-DPPQMTKAALVKAPP 374
+S P++++ L D P+M+ L + P
Sbjct: 487 FSEVPVQLRELTLDMPKMSCWNLARGYP 514
>AL031117-4|CAA19965.1| 641|Homo sapiens calpain 6 protein.
Length = 641
Score = 69.3 bits (162), Expect = 3e-11
Identities = 75/268 (27%), Positives = 120/268 (44%), Gaps = 31/268 (11%)
Query: 124 KIRLRRSVINIFQVDTTNEPVYLIRLRRPLGHGET--PISHIVLDTALWKTIPQYERDRL 181
KIRL ++ +F E VY++RLR PLG E P S I + W+ + +R L
Sbjct: 261 KIRLGERLVEVFSA----EKVYMVRLRNPLGRQEWSGPWSEISEE---WQQLTASDRKNL 313
Query: 182 ---MTASKGVWMLFSDFQRLFPRIEMVHLDTET--SRAELSLSEKQKWQMKMHQGGWKRG 236
M+ WM DF R F ++ + R EL S W + R
Sbjct: 314 GLVMSDDGEFWMSLEDFCRNFHKLNVCRNVNNPIFGRKELE-SVLGCWTVD-DDPLMNR- 370
Query: 237 VSAGGCRNYVNFFHTNPQVQIMLNEPD-TVIISLNQHSIMEPK--------VIGFSVYKM 287
+GGC N + F NPQ + E VI+SL Q + + +IGF ++K+
Sbjct: 371 --SGGCYNNRDTFLQNPQYIFTVPEDGHKVIMSLQQKDLRTYRRMGRPDNYIIGFELFKV 428
Query: 288 PKFLTETANQMFFKRIKSTINSQYTNSRQVSQRCQLESGAYLIMPTTFEPREEAQFTLRI 347
+ ++ + T S Y ++R V L+ G Y+++PT F+ ++F LRI
Sbjct: 429 EMNRKFRLHHLYIQERAGT--STYIDTRTVFLSKYLKKGNYVLVPTMFQHGRTSEFLLRI 486
Query: 348 YSNKPLKMKVLD-DPPQMTKAALVKAPP 374
+S P++++ L D P+M+ L + P
Sbjct: 487 FSEVPVQLRELTLDMPKMSCWNLARGYP 514
>AJ000388-1|CAA04051.1| 641|Homo sapiens calpain-like protease,
CANPX protein.
Length = 641
Score = 69.3 bits (162), Expect = 3e-11
Identities = 75/268 (27%), Positives = 120/268 (44%), Gaps = 31/268 (11%)
Query: 124 KIRLRRSVINIFQVDTTNEPVYLIRLRRPLGHGET--PISHIVLDTALWKTIPQYERDRL 181
KIRL ++ +F E VY++RLR PLG E P S I + W+ + +R L
Sbjct: 261 KIRLGERLVEVFSA----EKVYMVRLRNPLGRQEWSGPWSEISEE---WQQLTASDRKNL 313
Query: 182 ---MTASKGVWMLFSDFQRLFPRIEMVHLDTET--SRAELSLSEKQKWQMKMHQGGWKRG 236
M+ WM DF R F ++ + R EL S W + R
Sbjct: 314 GLVMSDDGEFWMSLEDFCRNFHKLNVCRNVNNPIFGRKELE-SVLGCWTVD-DDPLMNR- 370
Query: 237 VSAGGCRNYVNFFHTNPQVQIMLNEPD-TVIISLNQHSIMEPK--------VIGFSVYKM 287
+GGC N + F NPQ + E VI+SL Q + + +IGF ++K+
Sbjct: 371 --SGGCYNNRDTFLQNPQYIFTVPEDGHKVIMSLQQKDLRTYRRMGRPDNYIIGFELFKV 428
Query: 288 PKFLTETANQMFFKRIKSTINSQYTNSRQVSQRCQLESGAYLIMPTTFEPREEAQFTLRI 347
+ ++ + T S Y ++R V L+ G Y+++PT F+ ++F LRI
Sbjct: 429 EMNRKFRLHHLYIQERAGT--STYIDTRTVFLSKYLKKGNYVLVPTMFQHGRTSEFLLRI 486
Query: 348 YSNKPLKMKVLD-DPPQMTKAALVKAPP 374
+S P++++ L D P+M+ L + P
Sbjct: 487 FSEVPVQLRELTLDMPKMSCWNLARGYP 514
>AF029232-1|AAB86605.1| 641|Homo sapiens calpamodulin protein.
Length = 641
Score = 69.3 bits (162), Expect = 3e-11
Identities = 75/268 (27%), Positives = 120/268 (44%), Gaps = 31/268 (11%)
Query: 124 KIRLRRSVINIFQVDTTNEPVYLIRLRRPLGHGET--PISHIVLDTALWKTIPQYERDRL 181
KIRL ++ +F E VY++RLR PLG E P S I + W+ + +R L
Sbjct: 261 KIRLGERLVEVFSA----EKVYMVRLRNPLGRQEWSGPWSEISEE---WQQLTASDRKNL 313
Query: 182 ---MTASKGVWMLFSDFQRLFPRIEMVHLDTET--SRAELSLSEKQKWQMKMHQGGWKRG 236
M+ WM DF R F ++ + R EL S W + R
Sbjct: 314 GLVMSDDGEFWMSLEDFCRNFHKLNVCRNVNNPIFGRKELE-SVLGCWTVD-DDPLMNR- 370
Query: 237 VSAGGCRNYVNFFHTNPQVQIMLNEPD-TVIISLNQHSIMEPK--------VIGFSVYKM 287
+GGC N + F NPQ + E VI+SL Q + + +IGF ++K+
Sbjct: 371 --SGGCYNNRDTFLQNPQYIFTVPEDGHKVIMSLQQKDLRTYRRMGKTDNYIIGFELFKV 428
Query: 288 PKFLTETANQMFFKRIKSTINSQYTNSRQVSQRCQLESGAYLIMPTTFEPREEAQFTLRI 347
+ ++ + T S Y ++R V L+ G Y+++PT F+ ++F LRI
Sbjct: 429 EMNRKFRLHHLYIQERAGT--STYIDTRTVFLSKYLKKGNYVLVPTMFQHGRTSEFLLRI 486
Query: 348 YSNKPLKMKVLD-DPPQMTKAALVKAPP 374
+S P++++ L D P+M+ L + P
Sbjct: 487 FSEVPVQLRELTLDMPKMSCWNLARGYP 514
>AF089090-1|AAG17968.1| 544|Homo sapiens calpain-like protease
CAPN10b protein.
Length = 544
Score = 64.9 bits (151), Expect = 6e-10
Identities = 78/344 (22%), Positives = 137/344 (39%), Gaps = 38/344 (11%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVMPELSDGSALRTLLDTSSVVTAH---YFPP 105
++HGSYE L G + D L DLTGG+ E + ++ + T +
Sbjct: 157 KVHGSYEHLWAGQVADALVDLTGGLAERWNLKGVAGSGGQQDRPGRWEHRTCRQLLHLKD 216
Query: 106 VTIISVFFLSLPTGIRLVKIRLRRSVINIFQVD-TTNEPVYLIRLRRPLGHGETPISHIV 164
+IS LS G R + V ++ ++ + + L+R++ P G
Sbjct: 217 QCLISCCVLSPRAGARELGEFHAFIVSDLRELQGQAGQCILLLRIQNPWGRRCWQGLWRE 276
Query: 165 LDTALWKTIPQYERDRLMTA-SKG-VWMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQ 222
W + L++ +G W+ +F R F + + + TE + +E+
Sbjct: 277 GGEG-WSQVDAAVASELLSQLQEGEFWVEEEEFLREFDELTVGYPVTEAGHLQSLYTERL 335
Query: 223 KWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPDTVIISLNQ----------- 271
+ G W +G SAGGCRN F +NP+ + ++EP V I++ Q
Sbjct: 336 LCHTRALPGAWVKGQSAGGCRNNSGF-PSNPKFWLRVSEPSEVYIAVLQRSRLHAADWAG 394
Query: 272 ---------HSIMEP--------KVIGFSVYKMPKFLTETANQMFFKRIKSTINSQYTNS 314
H+ P + +G ++K+ K + + T Y
Sbjct: 395 RARALVGDSHTSWSPASIPGKHYQAVGLHLWKVEKRRVNLPRVLSMPPVAGTACHAY--D 452
Query: 315 RQVSQRCQLESGAYLIMPTTFEPREEAQFTLRIYSNKPLKMKVL 358
R+V RC+L G YL +P+TF +F LR++S + ++ L
Sbjct: 453 REVHLRCELSPGYYLAVPSTFLKDAPGEFLLRVFSTGRVSLRAL 496
>AK074807-1|BAC11220.1| 672|Homo sapiens protein ( Homo sapiens
cDNA FLJ90326 fis, clone NT2RP2001903, weakly similar to
CALPAIN, LARGE [CATALYTIC] SUBUNIT (EC 3.4.22.17). ).
Length = 672
Score = 63.7 bits (148), Expect = 1e-09
Identities = 77/344 (22%), Positives = 137/344 (39%), Gaps = 38/344 (11%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVMPELSDGSALRTLLDTSSVVTAH---YFPP 105
++HGSYE L G + D L DLTGG+ E + ++ + + T +
Sbjct: 157 KVHGSYEHLWAGQVADALVDLTGGLAERWNLKGVAGSGSQQDRPGRWEHRTCRQLLHLKD 216
Query: 106 VTIISVFFLSLPTGIRLVKIRLRRSVINIFQVD-TTNEPVYLIRLRRPLGHGETPISHIV 164
+IS LS G R + V ++ ++ + + L+R++ P G
Sbjct: 217 QCLISCCVLSPRAGARELGEFHAFIVSDLRELQGQAGQCILLLRIQNPWGRRCWQGLWRE 276
Query: 165 LDTALWKTIPQYERDRLMTA-SKG-VWMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQ 222
W + L++ +G W+ +F R F + + + TE + +E+
Sbjct: 277 GGEG-WSQVDAAVASELLSQLQEGEFWVEEEEFLREFDELTVGYPVTEAGHLQSLYTERL 335
Query: 223 KWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPDTVIISLNQ----------- 271
+ G W +G SAGGCRN F +NP+ + ++EP V I++ Q
Sbjct: 336 LCHTRALPGAWVKGQSAGGCRNNSGF-PSNPKFWLRVSEPSEVYIAVLQRSRLHAADWAG 394
Query: 272 ---------HSIMEP--------KVIGFSVYKMPKFLTETANQMFFKRIKSTINSQYTNS 314
H+ P + +G ++K+ K + + T Y
Sbjct: 395 RARALVGDSHTSWSPASIPGKHYQAVGLHLWKVEKRRVNLPRVLSMPPVAGTACHAY--D 452
Query: 315 RQVSQRCQLESGAYLIMPTTFEPREEAQFTLRIYSNKPLKMKVL 358
R+V RC+L G YL +P+TF +F LR++S + + +
Sbjct: 453 REVHLRCELSPGYYLAVPSTFLKDAPGEFLLRVFSTGRVSLSAI 496
Score = 60.1 bits (139), Expect = 2e-08
Identities = 41/133 (30%), Positives = 73/133 (54%), Gaps = 11/133 (8%)
Query: 223 KWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNE---PDTVIISLNQH---SIME 276
+W +G W+ G +AGG RN+ ++ TNP + E P V I+L+QH S E
Sbjct: 513 EWGTVQLRGSWRVGQTAGGSRNFASY-PTNPCFPFSVPEGPGPRCVRITLHQHCRPSDTE 571
Query: 277 PKVIGFSVYKMPKF-LTETANQMFFKR-IKSTINSQYTNSRQVSQRCQLESGAYLIMPTT 334
IGF ++++P+ ++ A + + + S + +Y +++VS+ C L +G Y ++P+T
Sbjct: 572 FHPIGFHIFQVPEGGRSQDAPPLLLQEPLLSCVPHRY--AQEVSRLCLLPAGTYKVVPST 629
Query: 335 FEPREEAQFTLRI 347
+ P E FT+ I
Sbjct: 630 YLPDTEGAFTVTI 642
>BC007553-1|AAH07553.2| 672|Homo sapiens calpain 10 protein.
Length = 672
Score = 63.3 bits (147), Expect = 2e-09
Identities = 77/344 (22%), Positives = 136/344 (39%), Gaps = 38/344 (11%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVMPELSDGSALRTLLDTSSVVTAH---YFPP 105
++HGSYE L G + D L DLTGG+ E + ++ + T +
Sbjct: 157 KVHGSYEHLWAGQVADALVDLTGGLAERWNLKGVAGSGGQQDRPGRWEHRTCRQLLHLKD 216
Query: 106 VTIISVFFLSLPTGIRLVKIRLRRSVINIFQVD-TTNEPVYLIRLRRPLGHGETPISHIV 164
+IS LS G R + V ++ ++ + + L+R++ P G
Sbjct: 217 QCLISCCVLSPRAGARELGEFHAFIVSDLRELQGQAGQCILLLRIQNPWGRRCWQGLWRE 276
Query: 165 LDTALWKTIPQYERDRLMTA-SKG-VWMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQ 222
W + L++ +G W+ +F R F + + + TE + +E+
Sbjct: 277 GGEG-WSQVDAAVASELLSQLQEGEFWVEEEEFLREFDELTVGYPVTEAGHLQSLYTERL 335
Query: 223 KWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPDTVIISLNQ----------- 271
+ G W +G SAGGCRN F +NP+ + ++EP V I++ Q
Sbjct: 336 LCHTRALPGAWVKGQSAGGCRNNSGF-PSNPKFWLRVSEPSEVYIAVLQRSRLHAADWAG 394
Query: 272 ---------HSIMEP--------KVIGFSVYKMPKFLTETANQMFFKRIKSTINSQYTNS 314
H+ P + +G ++K+ K + + T Y
Sbjct: 395 RARALVGDSHTSWSPASIPGKHYQAVGLHLWKVEKRRVNLPRVLSMPPVAGTACHAY--D 452
Query: 315 RQVSQRCQLESGAYLIMPTTFEPREEAQFTLRIYSNKPLKMKVL 358
R+V RC+L G YL +P+TF +F LR++S + + +
Sbjct: 453 REVHLRCELSPGYYLAVPSTFLKDAPGEFLLRVFSTGRVSLSAI 496
Score = 60.1 bits (139), Expect = 2e-08
Identities = 41/133 (30%), Positives = 73/133 (54%), Gaps = 11/133 (8%)
Query: 223 KWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNE---PDTVIISLNQH---SIME 276
+W +G W+ G +AGG RN+ ++ TNP + E P V I+L+QH S E
Sbjct: 513 EWGTVQLRGSWRVGQTAGGSRNFASY-PTNPCFPFSVPEGPGPRCVRITLHQHCRPSDTE 571
Query: 277 PKVIGFSVYKMPKF-LTETANQMFFKR-IKSTINSQYTNSRQVSQRCQLESGAYLIMPTT 334
IGF ++++P+ ++ A + + + S + +Y +++VS+ C L +G Y ++P+T
Sbjct: 572 FHPIGFHIFQVPEGGRSQDAPPLLLQEPLLSCVPHRY--AQEVSRLCLLPAGTYKVVPST 629
Query: 335 FEPREEAQFTLRI 347
+ P E FT+ I
Sbjct: 630 YLPDTEGAFTVTI 642
>BC004260-1|AAH04260.1| 672|Homo sapiens calpain 10 protein.
Length = 672
Score = 63.3 bits (147), Expect = 2e-09
Identities = 77/344 (22%), Positives = 136/344 (39%), Gaps = 38/344 (11%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVMPELSDGSALRTLLDTSSVVTAH---YFPP 105
++HGSYE L G + D L DLTGG+ E + ++ + T +
Sbjct: 157 KVHGSYEHLWAGQVADALVDLTGGLAERWNLKGVAGSGGQQDRPGRWEHRTCRQLLHLKD 216
Query: 106 VTIISVFFLSLPTGIRLVKIRLRRSVINIFQVD-TTNEPVYLIRLRRPLGHGETPISHIV 164
+IS LS G R + V ++ ++ + + L+R++ P G
Sbjct: 217 QCLISCCVLSPRAGARELGEFHAFIVSDLRELQGQAGQCILLLRIQNPWGRRCWQGLWRE 276
Query: 165 LDTALWKTIPQYERDRLMTA-SKG-VWMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQ 222
W + L++ +G W+ +F R F + + + TE + +E+
Sbjct: 277 GGEG-WSQVDAAVASELLSQLQEGEFWVEEEEFLREFDELTVGYPVTEAGHLQSLYTERL 335
Query: 223 KWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPDTVIISLNQ----------- 271
+ G W +G SAGGCRN F +NP+ + ++EP V I++ Q
Sbjct: 336 LCHTRALPGAWVKGQSAGGCRNNSGF-PSNPKFWLRVSEPSEVYIAVLQRSRLHAADWAG 394
Query: 272 ---------HSIMEP--------KVIGFSVYKMPKFLTETANQMFFKRIKSTINSQYTNS 314
H+ P + +G ++K+ K + + T Y
Sbjct: 395 RARALVGDSHTSWSPASIPGKHYQAVGLHLWKVEKRRVNLPRVLSMPPVAGTACHAY--D 452
Query: 315 RQVSQRCQLESGAYLIMPTTFEPREEAQFTLRIYSNKPLKMKVL 358
R+V RC+L G YL +P+TF +F LR++S + + +
Sbjct: 453 REVHLRCELSPGYYLAVPSTFLKDAPGEFLLRVFSTGRVSLSAI 496
Score = 60.1 bits (139), Expect = 2e-08
Identities = 41/133 (30%), Positives = 73/133 (54%), Gaps = 11/133 (8%)
Query: 223 KWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNE---PDTVIISLNQH---SIME 276
+W +G W+ G +AGG RN+ ++ TNP + E P V I+L+QH S E
Sbjct: 513 EWGTVQLRGSWRVGQTAGGSRNFASY-PTNPCFPFSVPEGPGPRCVRITLHQHCRPSDTE 571
Query: 277 PKVIGFSVYKMPKF-LTETANQMFFKR-IKSTINSQYTNSRQVSQRCQLESGAYLIMPTT 334
IGF ++++P+ ++ A + + + S + +Y +++VS+ C L +G Y ++P+T
Sbjct: 572 FHPIGFHIFQVPEGGRSQDAPPLLLQEPLLSCVPHRY--AQEVSRLCLLPAGTYKVVPST 629
Query: 335 FEPREEAQFTLRI 347
+ P E FT+ I
Sbjct: 630 YLPDTEGAFTVTI 642
>AF089092-1|AAG17970.1| 513|Homo sapiens calpain-like protease
CAPN10d protein.
Length = 513
Score = 63.3 bits (147), Expect = 2e-09
Identities = 77/342 (22%), Positives = 136/342 (39%), Gaps = 38/342 (11%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVMPELSDGSALRTLLDTSSVVTAH---YFPP 105
++HGSYE L G + D L DLTGG+ E + ++ + T +
Sbjct: 157 KVHGSYEHLWAGQVADALVDLTGGLAERWNLKGVAGSGGQQDRPGRWEHRTCRQLLHLKD 216
Query: 106 VTIISVFFLSLPTGIRLVKIRLRRSVINIFQVD-TTNEPVYLIRLRRPLGHGETPISHIV 164
+IS LS G R + V ++ ++ + + L+R++ P G
Sbjct: 217 QCLISCCVLSPRAGARELGEFHAFIVSDLRELQGQAGQCILLLRIQNPWGRRCWQGLWRE 276
Query: 165 LDTALWKTIPQYERDRLMTA-SKG-VWMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQ 222
W + L++ +G W+ +F R F + + + TE + +E+
Sbjct: 277 GGEG-WSQVDAAVASELLSQLQEGEFWVEEEEFLREFDELTVGYPVTEAGHLQSLYTERL 335
Query: 223 KWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPDTVIISLNQ----------- 271
+ G W +G SAGGCRN F +NP+ + ++EP V I++ Q
Sbjct: 336 LCHTRALPGAWVKGQSAGGCRNNSGF-PSNPKFWLRVSEPSEVYIAVLQRSRLHAADWAG 394
Query: 272 ---------HSIMEP--------KVIGFSVYKMPKFLTETANQMFFKRIKSTINSQYTNS 314
H+ P + +G ++K+ K + + T Y
Sbjct: 395 RARALVGDSHTSWSPASIPGKHYQAVGLHLWKVEKRRVNLPRVLSMPPVAGTACHAY--D 452
Query: 315 RQVSQRCQLESGAYLIMPTTFEPREEAQFTLRIYSNKPLKMK 356
R+V RC+L G YL +P+TF +F LR++S + ++
Sbjct: 453 REVHLRCELSPGYYLAVPSTFLKDAPGEFLLRVFSTGRVSLR 494
>AF089088-1|AAG17966.1| 672|Homo sapiens calpain-like protease
CAPN10a protein.
Length = 672
Score = 63.3 bits (147), Expect = 2e-09
Identities = 77/344 (22%), Positives = 136/344 (39%), Gaps = 38/344 (11%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVMPELSDGSALRTLLDTSSVVTAH---YFPP 105
++HGSYE L G + D L DLTGG+ E + ++ + T +
Sbjct: 157 KVHGSYEHLWAGQVADALVDLTGGLAERWNLKGVAGSGGQQDRPGRWEHRTCRQLLHLKD 216
Query: 106 VTIISVFFLSLPTGIRLVKIRLRRSVINIFQVD-TTNEPVYLIRLRRPLGHGETPISHIV 164
+IS LS G R + V ++ ++ + + L+R++ P G
Sbjct: 217 QCLISCCVLSPRAGARELGEFHAFIVSDLRELQGQAGQCILLLRIQNPWGRRCWQGLWRE 276
Query: 165 LDTALWKTIPQYERDRLMTA-SKG-VWMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQ 222
W + L++ +G W+ +F R F + + + TE + +E+
Sbjct: 277 GGEG-WSQVDAAVASELLSQLQEGEFWVEEEEFLREFDELTVGYPVTEAGHLQSLYTERL 335
Query: 223 KWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPDTVIISLNQ----------- 271
+ G W +G SAGGCRN F +NP+ + ++EP V I++ Q
Sbjct: 336 LCHTRALPGAWVKGQSAGGCRNNSGF-PSNPKFWLRVSEPSEVYIAVLQRSRLHAADWAG 394
Query: 272 ---------HSIMEP--------KVIGFSVYKMPKFLTETANQMFFKRIKSTINSQYTNS 314
H+ P + +G ++K+ K + + T Y
Sbjct: 395 RARALVGDSHTSWSPASIPGKHYQAVGLHLWKVEKRRVNLPRVLSMPPVAGTACHAY--D 452
Query: 315 RQVSQRCQLESGAYLIMPTTFEPREEAQFTLRIYSNKPLKMKVL 358
R+V RC+L G YL +P+TF +F LR++S + + +
Sbjct: 453 REVHLRCELSPGYYLAVPSTFLKDAPGEFLLRVFSTGRVSLSAI 496
Score = 60.1 bits (139), Expect = 2e-08
Identities = 41/133 (30%), Positives = 73/133 (54%), Gaps = 11/133 (8%)
Query: 223 KWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNE---PDTVIISLNQH---SIME 276
+W +G W+ G +AGG RN+ ++ TNP + E P V I+L+QH S E
Sbjct: 513 EWGTVQLRGSWRVGQTAGGSRNFASY-PTNPCFPFSVPEGPGPRCVRITLHQHCRPSDTE 571
Query: 277 PKVIGFSVYKMPKF-LTETANQMFFKR-IKSTINSQYTNSRQVSQRCQLESGAYLIMPTT 334
IGF ++++P+ ++ A + + + S + +Y +++VS+ C L +G Y ++P+T
Sbjct: 572 FHPIGFHIFQVPEGGRSQDAPPLLLQEPLLSCVPHRY--AQEVSRLCLLPAGTYKVVPST 629
Query: 335 FEPREEAQFTLRI 347
+ P E FT+ I
Sbjct: 630 YLPDTEGAFTVTI 642
>AC124862-2|AAX88944.1| 672|Homo sapiens unknown protein.
Length = 672
Score = 63.3 bits (147), Expect = 2e-09
Identities = 77/344 (22%), Positives = 136/344 (39%), Gaps = 38/344 (11%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVMPELSDGSALRTLLDTSSVVTAH---YFPP 105
++HGSYE L G + D L DLTGG+ E + ++ + T +
Sbjct: 157 KVHGSYEHLWAGQVADALVDLTGGLAERWNLKGVAGSGGQQDRPGRWEHRTCRQLLHLKD 216
Query: 106 VTIISVFFLSLPTGIRLVKIRLRRSVINIFQVD-TTNEPVYLIRLRRPLGHGETPISHIV 164
+IS LS G R + V ++ ++ + + L+R++ P G
Sbjct: 217 QCLISCCVLSPRAGARELGEFHAFIVSDLRELQGQAGQCILLLRIQNPWGRRCWQGLWRE 276
Query: 165 LDTALWKTIPQYERDRLMTA-SKG-VWMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQ 222
W + L++ +G W+ +F R F + + + TE + +E+
Sbjct: 277 GGEG-WSQVDAAVASELLSQLQEGEFWVEEEEFLREFDELTVGYPVTEAGHLQSLYTERL 335
Query: 223 KWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPDTVIISLNQ----------- 271
+ G W +G SAGGCRN F +NP+ + ++EP V I++ Q
Sbjct: 336 LCHTRALPGAWVKGQSAGGCRNNSGF-PSNPKFWLRVSEPSEVYIAVLQRSRLHAADWAG 394
Query: 272 ---------HSIMEP--------KVIGFSVYKMPKFLTETANQMFFKRIKSTINSQYTNS 314
H+ P + +G ++K+ K + + T Y
Sbjct: 395 RARALVGDSHTSWSPASIPGKHYQAVGLHLWKVEKRRVNLPRVLSMPPVAGTACHAY--D 452
Query: 315 RQVSQRCQLESGAYLIMPTTFEPREEAQFTLRIYSNKPLKMKVL 358
R+V RC+L G YL +P+TF +F LR++S + + +
Sbjct: 453 REVHLRCELSPGYYLAVPSTFLKDAPGEFLLRVFSTGRVSLSAI 496
Score = 60.1 bits (139), Expect = 2e-08
Identities = 41/133 (30%), Positives = 73/133 (54%), Gaps = 11/133 (8%)
Query: 223 KWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNE---PDTVIISLNQH---SIME 276
+W +G W+ G +AGG RN+ ++ TNP + E P V I+L+QH S E
Sbjct: 513 EWGTVQLRGSWRVGQTAGGSRNFASY-PTNPCFPFSVPEGPGPRCVRITLHQHCRPSDTE 571
Query: 277 PKVIGFSVYKMPKF-LTETANQMFFKR-IKSTINSQYTNSRQVSQRCQLESGAYLIMPTT 334
IGF ++++P+ ++ A + + + S + +Y +++VS+ C L +G Y ++P+T
Sbjct: 572 FHPIGFHIFQVPEGGRSQDAPPLLLQEPLLSCVPHRY--AQEVSRLCLLPAGTYKVVPST 629
Query: 335 FEPREEAQFTLRI 347
+ P E FT+ I
Sbjct: 630 YLPDTEGAFTVTI 642
>AB058748-1|BAB47474.1| 705|Homo sapiens KIAA1845 protein protein.
Length = 705
Score = 63.3 bits (147), Expect = 2e-09
Identities = 77/344 (22%), Positives = 136/344 (39%), Gaps = 38/344 (11%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVMPELSDGSALRTLLDTSSVVTAH---YFPP 105
++HGSYE L G + D L DLTGG+ E + ++ + T +
Sbjct: 190 KVHGSYEHLWAGQVADALVDLTGGLAERWNLKGVAGSGGQQDRPGRWEHRTCRQLLHLKD 249
Query: 106 VTIISVFFLSLPTGIRLVKIRLRRSVINIFQVD-TTNEPVYLIRLRRPLGHGETPISHIV 164
+IS LS G R + V ++ ++ + + L+R++ P G
Sbjct: 250 QCLISCCVLSPRAGARELGEFHAFIVSDLRELQGQAGQCILLLRIQNPWGRRCWQGLWRE 309
Query: 165 LDTALWKTIPQYERDRLMTA-SKG-VWMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQ 222
W + L++ +G W+ +F R F + + + TE + +E+
Sbjct: 310 GGEG-WSQVDAAVASELLSQLQEGEFWVEEEEFLREFDELTVGYPVTEAGHLQSLYTERL 368
Query: 223 KWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPDTVIISLNQ----------- 271
+ G W +G SAGGCRN F +NP+ + ++EP V I++ Q
Sbjct: 369 LCHTRALPGAWVKGQSAGGCRNNSGF-PSNPKFWLRVSEPSEVYIAVLQRSRLHAADWAG 427
Query: 272 ---------HSIMEP--------KVIGFSVYKMPKFLTETANQMFFKRIKSTINSQYTNS 314
H+ P + +G ++K+ K + + T Y
Sbjct: 428 RARALVGDSHTSWSPASIPGKHYQAVGLHLWKVEKRRVNLPRVLSMPPVAGTACHAY--D 485
Query: 315 RQVSQRCQLESGAYLIMPTTFEPREEAQFTLRIYSNKPLKMKVL 358
R+V RC+L G YL +P+TF +F LR++S + + +
Sbjct: 486 REVHLRCELSPGYYLAVPSTFLKDAPGEFLLRVFSTGRVSLSAI 529
Score = 60.1 bits (139), Expect = 2e-08
Identities = 41/133 (30%), Positives = 73/133 (54%), Gaps = 11/133 (8%)
Query: 223 KWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNE---PDTVIISLNQH---SIME 276
+W +G W+ G +AGG RN+ ++ TNP + E P V I+L+QH S E
Sbjct: 546 EWGTVQLRGSWRVGQTAGGSRNFASY-PTNPCFPFSVPEGPGPRCVRITLHQHCRPSDTE 604
Query: 277 PKVIGFSVYKMPKF-LTETANQMFFKR-IKSTINSQYTNSRQVSQRCQLESGAYLIMPTT 334
IGF ++++P+ ++ A + + + S + +Y +++VS+ C L +G Y ++P+T
Sbjct: 605 FHPIGFHIFQVPEGGRSQDAPPLLLQEPLLSCVPHRY--AQEVSRLCLLPAGTYKVVPST 662
Query: 335 FEPREEAQFTLRI 347
+ P E FT+ I
Sbjct: 663 YLPDTEGAFTVTI 675
>AK124751-1|BAC85936.1| 210|Homo sapiens protein ( Homo sapiens
cDNA FLJ42761 fis, clone BRAWH3002574, highly similar
to Calpain 2, large [catalytic] subunit precursor (EC
3.4.22.17). ).
Length = 210
Score = 58.8 bits (136), Expect = 4e-08
Identities = 40/134 (29%), Positives = 64/134 (47%), Gaps = 6/134 (4%)
Query: 311 YTNSRQVSQRCQLESGAYLIMPTTFEPREEAQFTLRIYSNKPLKMKVLDDPPQMTKAALV 370
+ N R+V R +L G Y+++P+TFEP ++ F +R++S K + +DD +
Sbjct: 48 FINLREVLNRFKLPPGEYILVPSTFEPNKDGDFCIRVFSEKKADYQAVDDEIEANLEEFD 107
Query: 371 KAPPGSDSNGFFQYETLFLQLADAHRTIDIFELQELLDACLP--NDYIKSCVSIDTLKHL 428
+ D +GF LF QLA I FELQ +L L D SI+T K +
Sbjct: 108 ISEDDID-DGF---RRLFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIM 163
Query: 429 QLVFKTHAREKMGV 442
+ + K+G+
Sbjct: 164 VDMLDSDGSGKLGL 177
>AF089091-1|AAG17969.1| 517|Homo sapiens calpain-like protease
CAPN10c protein.
Length = 517
Score = 58.0 bits (134), Expect = 7e-08
Identities = 75/335 (22%), Positives = 141/335 (42%), Gaps = 40/335 (11%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVMPELSDGSALRTLLDTSSVVTAH---YFPP 105
++HGSYE L G + D L DLTGG+ E + ++ + T +
Sbjct: 157 KVHGSYEHLWAGQVADALVDLTGGLAERWNLKGVAGSGGQQDRPGRWEHRTCRQLLHLKD 216
Query: 106 VTIISVFFLSLPTGIRLVKIRLRRSVINIFQVD-TTNEPVYLIRLRRPLGHGETPISHIV 164
+IS LS G R + V ++ ++ + + L+R++ P G
Sbjct: 217 QCLISCCVLSPRAGARELGEFHAFIVSDLRELQGQAGQCILLLRIQNPWGRRCWQGLWRE 276
Query: 165 LDTALWKTIPQYERDRLMTA-SKG-VWMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQ 222
W + L++ +G W+ +F R F + + + TE + +E+
Sbjct: 277 GGEG-WSQVDAAVASELLSQLQEGEFWVEEEEFLREFDELTVGYPVTEAGHLQSLYTERL 335
Query: 223 KWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPDTVIISLNQ----------- 271
+ G W +G SAGGCRN F +NP+ + +++P V I++ Q
Sbjct: 336 LCHTRALPGAWVKGQSAGGCRNNSGF-PSNPKFWLRVSKPSEVYIAVLQRSRLHAADWAG 394
Query: 272 ---------HSIMEP--------KVIGFSVYKMPKF-LTETANQMFFKR-IKSTINSQYT 312
H+ P + +G ++K+P+ ++ A + + + S + +Y
Sbjct: 395 RARALVGDSHTSWSPASIPGKHYQAVGLHLWKVPEGGRSQDAPPLLLQEPLLSCVPHRY- 453
Query: 313 NSRQVSQRCQLESGAYLIMPTTFEPREEAQFTLRI 347
+++VS+ C L +G Y ++P+T+ P E FT+ I
Sbjct: 454 -AQEVSRLCLLPAGTYKVVPSTYLPDTEGAFTVTI 487
>AF089093-1|AAG17971.1| 444|Homo sapiens calpain-like protease
CAPN10e protein.
Length = 444
Score = 53.6 bits (123), Expect = 2e-06
Identities = 55/231 (23%), Positives = 98/231 (42%), Gaps = 8/231 (3%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVMPELSDGSALRTLLDTSSVVTAH---YFPP 105
++HGSYE L G + D L DLTGG+ E + ++ + T +
Sbjct: 157 KVHGSYEHLWAGQVADALVDLTGGLAERWNLKGVAGSGGQQDRPGRWEHRTCRQLLHLKD 216
Query: 106 VTIISVFFLSLPTGIRLVKIRLRRSVINIFQVD-TTNEPVYLIRLRRPLGHGETPISHIV 164
+IS LS G R + V ++ ++ + + L+R++ P G
Sbjct: 217 QCLISCCVLSPRAGARELGEFHAFIVSDLRELQGQAGQCILLLRIQNPWGRRCWQGLWRE 276
Query: 165 LDTALWKTIPQYERDRLMTA-SKG-VWMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQ 222
W + L++ +G W+ +F R F + + + TE + +E+
Sbjct: 277 GGEG-WSQVDAAVASELLSQLQEGEFWVEEEEFLREFDELTVGYPVTEAGHLQSLYTERL 335
Query: 223 KWQMKMHQGGWKRGVSAGGCRNYVNFFHTNPQVQIMLNEPDTVIISLNQHS 273
+ G W +G SAGGCRN + F +NP+ + +++P V I++ Q S
Sbjct: 336 LCHTRALPGAWVKGQSAGGCRNN-SGFPSNPKFWLRVSKPSEVYIAVLQRS 385
>BC006000-1|AAH06000.1| 248|Homo sapiens calpain, small subunit 2
protein.
Length = 248
Score = 50.8 bits (116), Expect = 1e-05
Identities = 24/72 (33%), Positives = 43/72 (59%)
Query: 423 DTLKHLQLVFKTHAREKMGVLRVERLRDALKDVGFIVPERVISLLVFRYMRKDGMLRFGD 482
+ +K Q V+K + R+ G L +LR AL+ GF + E++ ++V RY +DG + F +
Sbjct: 149 NNIKKWQCVYKQYDRDHSGSLGSSQLRGALQAAGFQLNEQLYQMIVRRYANEDGDMDFNN 208
Query: 483 FVSAVMHLHRVF 494
F+S ++ L +F
Sbjct: 209 FISCLVRLDAMF 220
>BC005397-1|AAH05397.1| 248|Homo sapiens calpain, small subunit 2
protein.
Length = 248
Score = 50.8 bits (116), Expect = 1e-05
Identities = 24/72 (33%), Positives = 43/72 (59%)
Query: 423 DTLKHLQLVFKTHAREKMGVLRVERLRDALKDVGFIVPERVISLLVFRYMRKDGMLRFGD 482
+ +K Q V+K + R+ G L +LR AL+ GF + E++ ++V RY +DG + F +
Sbjct: 149 NNIKKWQCVYKQYDRDHSGSLGSSQLRGALQAAGFQLNEQLYQMIVRRYANEDGDMDFNN 208
Query: 483 FVSAVMHLHRVF 494
F+S ++ L +F
Sbjct: 209 FISCLVRLDAMF 220
>AY052551-1|AAL02241.1| 248|Homo sapiens calpain small subunit 2
protein.
Length = 248
Score = 50.8 bits (116), Expect = 1e-05
Identities = 24/72 (33%), Positives = 43/72 (59%)
Query: 423 DTLKHLQLVFKTHAREKMGVLRVERLRDALKDVGFIVPERVISLLVFRYMRKDGMLRFGD 482
+ +K Q V+K + R+ G L +LR AL+ GF + E++ ++V RY +DG + F +
Sbjct: 149 NNIKKWQCVYKQYDRDHSGSLGSSQLRGALQAAGFQLNEQLYQMIVRRYANEDGDMDFNN 208
Query: 483 FVSAVMHLHRVF 494
F+S ++ L +F
Sbjct: 209 FISCLVRLDAMF 220
>BT007322-1|AAP35986.1| 309|Homo sapiens calpain 3, (p94) protein.
Length = 309
Score = 50.4 bits (115), Expect = 1e-05
Identities = 20/41 (48%), Positives = 30/41 (73%)
Query: 311 YTNSRQVSQRCQLESGAYLIMPTTFEPREEAQFTLRIYSNK 351
Y N R+VSQR +L Y+I+P+T+EP +E +F LR++S K
Sbjct: 25 YINMREVSQRFRLPPSEYVIVPSTYEPHQEGEFILRVFSEK 65
Score = 38.7 bits (86), Expect = 0.048
Identities = 18/76 (23%), Positives = 37/76 (48%)
Query: 425 LKHLQLVFKTHAREKMGVLRVERLRDALKDVGFIVPERVISLLVFRYMRKDGMLRFGDFV 484
+K Q +FK + ++ G + +R+A+ D GF + ++ ++ RY K + F F+
Sbjct: 212 IKAWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDIITMRYADKHMNIDFDSFI 271
Query: 485 SAVMHLHRVFVQVYDF 500
+ L +F + F
Sbjct: 272 CCFVRLEGMFRAFHAF 287
>BC003169-1|AAH03169.1| 309|Homo sapiens calpain 3, (p94) protein.
Length = 309
Score = 50.4 bits (115), Expect = 1e-05
Identities = 20/41 (48%), Positives = 30/41 (73%)
Query: 311 YTNSRQVSQRCQLESGAYLIMPTTFEPREEAQFTLRIYSNK 351
Y N R+VSQR +L Y+I+P+T+EP +E +F LR++S K
Sbjct: 25 YINMREVSQRFRLPPSEYVIVPSTYEPHQEGEFILRVFSEK 65
Score = 38.7 bits (86), Expect = 0.048
Identities = 18/76 (23%), Positives = 37/76 (48%)
Query: 425 LKHLQLVFKTHAREKMGVLRVERLRDALKDVGFIVPERVISLLVFRYMRKDGMLRFGDFV 484
+K Q +FK + ++ G + +R+A+ D GF + ++ ++ RY K + F F+
Sbjct: 212 IKAWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDIITMRYADKHMNIDFDSFI 271
Query: 485 SAVMHLHRVFVQVYDF 500
+ L +F + F
Sbjct: 272 CCFVRLEGMFRAFHAF 287
>BC117347-1|AAI17348.1| 669|Homo sapiens calpain 13 protein.
Length = 669
Score = 45.6 bits (103), Expect = 4e-04
Identities = 87/370 (23%), Positives = 145/370 (39%), Gaps = 28/370 (7%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVM--PELSDGSALRTLLDTSSVVTAHYFPPV 106
+L GSY L YG L D L DLTGG+ +I + + A++T S++T
Sbjct: 175 KLLGSYSDLHYGFLEDALVDLTGGVITNIHLHSSPVDLVKAVKTATKAGSLITCATPSGP 234
Query: 107 TIISVFFLSLPTGIRLVKIRLRRSVINIFQVDTTNEPVYLIRLRRPLGHGETPISHIVLD 166
T + ++ G LV + +V Q+ +I L P G GET D
Sbjct: 235 TDTA---QAMENG--LVSLH-AYTVTGAEQIQYRRGWEEIISLWNPWGWGETEWRGRWSD 288
Query: 167 -TALWKTIPQYERDRLMTASKG--VWMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQK 223
+ W+ + +L + WM DFQ+ F I M + + +
Sbjct: 289 GSQEWEETCDPRKSQLHKKREDGEFWMSCQDFQQKF--IAMFICSEIPITLDHGNTLHEG 346
Query: 224 WQMKMHQGGWKRGVSAGGCRN--YVNFFHTNPQVQIMLNEPDTVIISLNQHSIMEPKV-I 280
W M + G +AGG RN NF P + TV ++ + + K +
Sbjct: 347 WSQIMFRKQVILGNTAGGPRNDAQFNFSVQEPMEGTNVVVCVTVAVTPSNLKAEDAKFPL 406
Query: 281 GFSVYKM-PKFLTETANQMFFKRIKSTINSQYTN-SRQVSQRCQLESGAYLIMPTTFEPR 338
F V + E +FF ++T+ S R + L G Y+++ T R
Sbjct: 407 DFQVILAGSQRFREKFPPVFFSSFRNTVQSSNNKFRRNFTMTYHLSPGNYVVVAQT--RR 464
Query: 339 EEAQFTLRIYSNKPLKMKVLDDPPQMTKAALVKAPPGSDSNGFFQYETLFLQLADAHRTI 398
+ A+F LRI+ +K+ D ++ ++ +G +++F + A I
Sbjct: 465 KSAEFLLRIF------LKMPDSDRHLSSHFNLRMKGSPSEHG--SQQSIFNRYAQQRLDI 516
Query: 399 DIFELQELLD 408
D +LQ LL+
Sbjct: 517 DATQLQGLLN 526
>BC117345-1|AAI17346.1| 669|Homo sapiens calpain 13 protein.
Length = 669
Score = 45.6 bits (103), Expect = 4e-04
Identities = 87/370 (23%), Positives = 145/370 (39%), Gaps = 28/370 (7%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVM--PELSDGSALRTLLDTSSVVTAHYFPPV 106
+L GSY L YG L D L DLTGG+ +I + + A++T S++T
Sbjct: 175 KLLGSYSDLHYGFLEDALVDLTGGVITNIHLHSSPVDLVKAVKTATKAGSLITCATPSGP 234
Query: 107 TIISVFFLSLPTGIRLVKIRLRRSVINIFQVDTTNEPVYLIRLRRPLGHGETPISHIVLD 166
T + ++ G LV + +V Q+ +I L P G GET D
Sbjct: 235 TDTA---QAMENG--LVSLH-AYTVTGAEQIQYRRGWEEIISLWNPWGWGETEWRGRWSD 288
Query: 167 -TALWKTIPQYERDRLMTASKG--VWMLFSDFQRLFPRIEMVHLDTETSRAELSLSEKQK 223
+ W+ + +L + WM DFQ+ F I M + + +
Sbjct: 289 GSQEWEETCDPRKSQLHKKREDGEFWMSCQDFQQKF--IAMFICSEIPITLDHGNTLHEG 346
Query: 224 WQMKMHQGGWKRGVSAGGCRN--YVNFFHTNPQVQIMLNEPDTVIISLNQHSIMEPKV-I 280
W M + G +AGG RN NF P + TV ++ + + K +
Sbjct: 347 WSQIMFRKQVILGNTAGGPRNDAQFNFSVQEPMEGTNVVVCVTVAVTPSNLKAEDAKFPL 406
Query: 281 GFSVYKM-PKFLTETANQMFFKRIKSTINSQYTN-SRQVSQRCQLESGAYLIMPTTFEPR 338
F V + E +FF ++T+ S R + L G Y+++ T R
Sbjct: 407 DFQVILAGSQRFREKFPPVFFSSFRNTVQSSNNKFRRNFTMTYHLSPGNYVVVAQT--RR 464
Query: 339 EEAQFTLRIYSNKPLKMKVLDDPPQMTKAALVKAPPGSDSNGFFQYETLFLQLADAHRTI 398
+ A+F LRI+ +K+ D ++ ++ +G +++F + A I
Sbjct: 465 KSAEFLLRIF------LKMPDSDRHLSSHFNLRMKGSPSEHG--SQQSIFNRYAQQRLDI 516
Query: 399 DIFELQELLD 408
D +LQ LL+
Sbjct: 517 DATQLQGLLN 526
>Z97986-1|CAC14067.1| 1086|Homo sapiens small optic lobes homolog
(Drosophila) protein.
Length = 1086
Score = 44.8 bits (101), Expect = 7e-04
Identities = 54/179 (30%), Positives = 81/179 (45%), Gaps = 19/179 (10%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVMPELSDGSALRTLLDTSSVVTAHYFPPVTI 108
+LHGSY AL+ G ++GLA LTG ES+ + +LS + +DT ++ A
Sbjct: 631 KLHGSYFALQAGRAIEGLATLTGAPCESLAL-QLSSTNPREEPVDT-DLIWAKMLSSKEA 688
Query: 109 ISVFFLSLPTGIRLV------KIRLR-RSVINIFQVDTTNEPVYLIRLRRPLGHGETPIS 161
+ S G V + LR R +I V + L+RLR P G S
Sbjct: 689 GFLMGASCGGGNMKVDDSAYESLGLRPRHAYSILDVRDV-QGTRLLRLRNPWGRFSWNGS 747
Query: 162 HIVLDTALWKTIPQYERDRLMT--ASKGV-WMLFSDFQRLFPRIEM--VHLDTETSRAE 215
+ W P + R LM +S+GV WM + DF R F +++ VH D + +R +
Sbjct: 748 W----SDEWPHWPGHLRGELMPHGSSEGVFWMEYGDFVRYFDSVDICKVHSDWQEARVQ 802
>U85647-1|AAC33822.1| 1086|Homo sapiens small optic lobes homolog
protein.
Length = 1086
Score = 44.8 bits (101), Expect = 7e-04
Identities = 54/179 (30%), Positives = 81/179 (45%), Gaps = 19/179 (10%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVMPELSDGSALRTLLDTSSVVTAHYFPPVTI 108
+LHGSY AL+ G ++GLA LTG ES+ + +LS + +DT ++ A
Sbjct: 631 KLHGSYFALQAGRAIEGLATLTGAPCESLAL-QLSSTNPREEPVDT-DLIWAKMLSSKEA 688
Query: 109 ISVFFLSLPTGIRLV------KIRLR-RSVINIFQVDTTNEPVYLIRLRRPLGHGETPIS 161
+ S G V + LR R +I V + L+RLR P G S
Sbjct: 689 GFLMGASCGGGNMKVDDSAYESLGLRPRHAYSILDVRDV-QGTRLLRLRNPWGRFSWNGS 747
Query: 162 HIVLDTALWKTIPQYERDRLMT--ASKGV-WMLFSDFQRLFPRIEM--VHLDTETSRAE 215
+ W P + R LM +S+GV WM + DF R F +++ VH D + +R +
Sbjct: 748 W----SDEWPHWPGHLRGELMPHGSSEGVFWMEYGDFVRYFDSVDICKVHSDWQEARVQ 802
>BC021854-1|AAH21854.1| 562|Homo sapiens Similar to small optic
lobes homolog (Drosophila) protein.
Length = 562
Score = 44.8 bits (101), Expect = 7e-04
Identities = 54/179 (30%), Positives = 81/179 (45%), Gaps = 19/179 (10%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVMPELSDGSALRTLLDTSSVVTAHYFPPVTI 108
+LHGSY AL+ G ++GLA LTG ES+ + +LS + +DT ++ A
Sbjct: 107 KLHGSYFALQAGRAIEGLATLTGAPCESLAL-QLSSTNPREEPVDT-DLIWAKMLSSKEA 164
Query: 109 ISVFFLSLPTGIRLV------KIRLR-RSVINIFQVDTTNEPVYLIRLRRPLGHGETPIS 161
+ S G V + LR R +I V + L+RLR P G S
Sbjct: 165 GFLMGASCGGGNMKVDDSAYESLGLRPRHAYSILDVRDV-QGTRLLRLRNPWGRFSWNGS 223
Query: 162 HIVLDTALWKTIPQYERDRLMT--ASKGV-WMLFSDFQRLFPRIEM--VHLDTETSRAE 215
+ W P + R LM +S+GV WM + DF R F +++ VH D + +R +
Sbjct: 224 W----SDEWPHWPGHLRGELMPHGSSEGVFWMEYGDFVRYFDSVDICKVHSDWQEARVQ 278
>AE006464-1|AAK61233.1| 1086|Homo sapiens small optic lobes homolog
protein.
Length = 1086
Score = 44.8 bits (101), Expect = 7e-04
Identities = 54/179 (30%), Positives = 81/179 (45%), Gaps = 19/179 (10%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESIVMPELSDGSALRTLLDTSSVVTAHYFPPVTI 108
+LHGSY AL+ G ++GLA LTG ES+ + +LS + +DT ++ A
Sbjct: 631 KLHGSYFALQAGRAIEGLATLTGAPCESLAL-QLSSTNPREEPVDT-DLIWAKMLSSKEA 688
Query: 109 ISVFFLSLPTGIRLV------KIRLR-RSVINIFQVDTTNEPVYLIRLRRPLGHGETPIS 161
+ S G V + LR R +I V + L+RLR P G S
Sbjct: 689 GFLMGASCGGGNMKVDDSAYESLGLRPRHAYSILDVRDV-QGTRLLRLRNPWGRFSWNGS 747
Query: 162 HIVLDTALWKTIPQYERDRLMT--ASKGV-WMLFSDFQRLFPRIEM--VHLDTETSRAE 215
+ W P + R LM +S+GV WM + DF R F +++ VH D + +R +
Sbjct: 748 W----SDEWPHWPGHLRGELMPHGSSEGVFWMEYGDFVRYFDSVDICKVHSDWQEARVQ 802
>X04106-1|CAA27726.1| 268|Homo sapiens protein ( Human mRNA for
calcium dependent protease (small subunit). ).
Length = 268
Score = 39.5 bits (88), Expect = 0.028
Identities = 17/72 (23%), Positives = 38/72 (52%)
Query: 423 DTLKHLQLVFKTHAREKMGVLRVERLRDALKDVGFIVPERVISLLVFRYMRKDGMLRFGD 482
+ +K Q ++K ++ G + L A + GF + E + ++++ RY + G + F +
Sbjct: 169 NNIKRWQAIYKQFDTDRSGTICSSELPGAFEAAGFHLNEHLYNMIIRRYSDESGNMDFDN 228
Query: 483 FVSAVMHLHRVF 494
F+S ++ L +F
Sbjct: 229 FISCLVRLDAMF 240
>M31511-1|AAA35646.1| 268|Homo sapiens protein ( Human
calcium-activated neutral protease small subunit gene,
exon 11. ).
Length = 268
Score = 39.5 bits (88), Expect = 0.028
Identities = 17/72 (23%), Positives = 38/72 (52%)
Query: 423 DTLKHLQLVFKTHAREKMGVLRVERLRDALKDVGFIVPERVISLLVFRYMRKDGMLRFGD 482
+ +K Q ++K ++ G + L A + GF + E + ++++ RY + G + F +
Sbjct: 169 NNIKRWQAIYKQFDTDRSGTICSSELPGAFEAAGFHLNEHLYNMIIRRYSDESGNMDFDN 228
Query: 483 FVSAVMHLHRVF 494
F+S ++ L +F
Sbjct: 229 FISCLVRLDAMF 240
>BT009775-1|AAP88777.1| 268|Homo sapiens calpain, small subunit 1
protein.
Length = 268
Score = 39.5 bits (88), Expect = 0.028
Identities = 17/72 (23%), Positives = 38/72 (52%)
Query: 423 DTLKHLQLVFKTHAREKMGVLRVERLRDALKDVGFIVPERVISLLVFRYMRKDGMLRFGD 482
+ +K Q ++K ++ G + L A + GF + E + ++++ RY + G + F +
Sbjct: 169 NNIKRWQAIYKQFDTDRSGTICSSELPGAFEAAGFHLNEHLYNMIIRRYSDESGNMDFDN 228
Query: 483 FVSAVMHLHRVF 494
F+S ++ L +F
Sbjct: 229 FISCLVRLDAMF 240
>BC064998-1|AAH64998.1| 268|Homo sapiens CAPNS1 protein protein.
Length = 268
Score = 39.5 bits (88), Expect = 0.028
Identities = 17/72 (23%), Positives = 38/72 (52%)
Query: 423 DTLKHLQLVFKTHAREKMGVLRVERLRDALKDVGFIVPERVISLLVFRYMRKDGMLRFGD 482
+ +K Q ++K ++ G + L A + GF + E + ++++ RY + G + F +
Sbjct: 169 NNIKRWQAIYKQFDTDRSGTICSSELPGAFEAAGFHLNEHLYNMIIRRYSDESGNMDFDN 228
Query: 483 FVSAVMHLHRVF 494
F+S ++ L +F
Sbjct: 229 FISCLVRLDAMF 240
>BC023643-1|AAH23643.1| 268|Homo sapiens calpain, small subunit 1
protein.
Length = 268
Score = 39.5 bits (88), Expect = 0.028
Identities = 17/72 (23%), Positives = 38/72 (52%)
Query: 423 DTLKHLQLVFKTHAREKMGVLRVERLRDALKDVGFIVPERVISLLVFRYMRKDGMLRFGD 482
+ +K Q ++K ++ G + L A + GF + E + ++++ RY + G + F +
Sbjct: 169 NNIKRWQAIYKQFDTDRSGTICSSELPGAFEAAGFHLNEHLYNMIIRRYSDESGNMDFDN 228
Query: 483 FVSAVMHLHRVF 494
F+S ++ L +F
Sbjct: 229 FISCLVRLDAMF 240
>BC021933-1|AAH21933.1| 268|Homo sapiens calpain, small subunit 1
protein.
Length = 268
Score = 39.5 bits (88), Expect = 0.028
Identities = 17/72 (23%), Positives = 38/72 (52%)
Query: 423 DTLKHLQLVFKTHAREKMGVLRVERLRDALKDVGFIVPERVISLLVFRYMRKDGMLRFGD 482
+ +K Q ++K ++ G + L A + GF + E + ++++ RY + G + F +
Sbjct: 169 NNIKRWQAIYKQFDTDRSGTICSSELPGAFEAAGFHLNEHLYNMIIRRYSDESGNMDFDN 228
Query: 483 FVSAVMHLHRVF 494
F+S ++ L +F
Sbjct: 229 FISCLVRLDAMF 240
>BC018931-1|AAH18931.1| 268|Homo sapiens calpain, small subunit 1
protein.
Length = 268
Score = 39.5 bits (88), Expect = 0.028
Identities = 17/72 (23%), Positives = 38/72 (52%)
Query: 423 DTLKHLQLVFKTHAREKMGVLRVERLRDALKDVGFIVPERVISLLVFRYMRKDGMLRFGD 482
+ +K Q ++K ++ G + L A + GF + E + ++++ RY + G + F +
Sbjct: 169 NNIKRWQAIYKQFDTDRSGTICSSELPGAFEAAGFHLNEHLYNMIIRRYSDESGNMDFDN 228
Query: 483 FVSAVMHLHRVF 494
F+S ++ L +F
Sbjct: 229 FISCLVRLDAMF 240
>BC017308-1|AAH17308.1| 268|Homo sapiens calpain, small subunit 1
protein.
Length = 268
Score = 39.5 bits (88), Expect = 0.028
Identities = 17/72 (23%), Positives = 38/72 (52%)
Query: 423 DTLKHLQLVFKTHAREKMGVLRVERLRDALKDVGFIVPERVISLLVFRYMRKDGMLRFGD 482
+ +K Q ++K ++ G + L A + GF + E + ++++ RY + G + F +
Sbjct: 169 NNIKRWQAIYKQFDTDRSGTICSSELPGAFEAAGFHLNEHLYNMIIRRYSDESGNMDFDN 228
Query: 483 FVSAVMHLHRVF 494
F+S ++ L +F
Sbjct: 229 FISCLVRLDAMF 240
>BC011903-1|AAH11903.1| 322|Homo sapiens CAPNS1 protein protein.
Length = 322
Score = 39.5 bits (88), Expect = 0.028
Identities = 17/72 (23%), Positives = 38/72 (52%)
Query: 423 DTLKHLQLVFKTHAREKMGVLRVERLRDALKDVGFIVPERVISLLVFRYMRKDGMLRFGD 482
+ +K Q ++K ++ G + L A + GF + E + ++++ RY + G + F +
Sbjct: 169 NNIKRWQAIYKQFDTDRSGTICSSELPGAFEAAGFHLNEHLYNMIIRRYSDESGNMDFDN 228
Query: 483 FVSAVMHLHRVF 494
F+S ++ L +F
Sbjct: 229 FISCLVRLDAMF 240
>BC007779-1|AAH07779.1| 268|Homo sapiens calpain, small subunit 1
protein.
Length = 268
Score = 39.5 bits (88), Expect = 0.028
Identities = 17/72 (23%), Positives = 38/72 (52%)
Query: 423 DTLKHLQLVFKTHAREKMGVLRVERLRDALKDVGFIVPERVISLLVFRYMRKDGMLRFGD 482
+ +K Q ++K ++ G + L A + GF + E + ++++ RY + G + F +
Sbjct: 169 NNIKRWQAIYKQFDTDRSGTICSSELPGAFEAAGFHLNEHLYNMIIRRYSDESGNMDFDN 228
Query: 483 FVSAVMHLHRVF 494
F+S ++ L +F
Sbjct: 229 FISCLVRLDAMF 240
>BC000592-1|AAH00592.1| 268|Homo sapiens calpain, small subunit 1
protein.
Length = 268
Score = 39.5 bits (88), Expect = 0.028
Identities = 17/72 (23%), Positives = 38/72 (52%)
Query: 423 DTLKHLQLVFKTHAREKMGVLRVERLRDALKDVGFIVPERVISLLVFRYMRKDGMLRFGD 482
+ +K Q ++K ++ G + L A + GF + E + ++++ RY + G + F +
Sbjct: 169 NNIKRWQAIYKQFDTDRSGTICSSELPGAFEAAGFHLNEHLYNMIIRRYSDESGNMDFDN 228
Query: 483 FVSAVMHLHRVF 494
F+S ++ L +F
Sbjct: 229 FISCLVRLDAMF 240
>AY789642-1|AAV40829.1| 268|Homo sapiens calpain, small subunit 1
protein.
Length = 268
Score = 39.5 bits (88), Expect = 0.028
Identities = 17/72 (23%), Positives = 38/72 (52%)
Query: 423 DTLKHLQLVFKTHAREKMGVLRVERLRDALKDVGFIVPERVISLLVFRYMRKDGMLRFGD 482
+ +K Q ++K ++ G + L A + GF + E + ++++ RY + G + F +
Sbjct: 169 NNIKRWQAIYKQFDTDRSGTICSSELPGAFEAAGFHLNEHLYNMIIRRYSDESGNMDFDN 228
Query: 483 FVSAVMHLHRVF 494
F+S ++ L +F
Sbjct: 229 FISCLVRLDAMF 240
>AD001527-4|AAB51183.1| 268|Homo sapiens calcium-dependent
protease, small (regulatory) subunit (calpain)
(calcium-activ protein.
Length = 268
Score = 39.5 bits (88), Expect = 0.028
Identities = 17/72 (23%), Positives = 38/72 (52%)
Query: 423 DTLKHLQLVFKTHAREKMGVLRVERLRDALKDVGFIVPERVISLLVFRYMRKDGMLRFGD 482
+ +K Q ++K ++ G + L A + GF + E + ++++ RY + G + F +
Sbjct: 169 NNIKRWQAIYKQFDTDRSGTICSSELPGAFEAAGFHLNEHLYNMIIRRYSDESGNMDFDN 228
Query: 483 FVSAVMHLHRVF 494
F+S ++ L +F
Sbjct: 229 FISCLVRLDAMF 240
>AC002984-1|AAB81546.1| 268|Homo sapiens CANS_Human protein.
Length = 268
Score = 39.5 bits (88), Expect = 0.028
Identities = 17/72 (23%), Positives = 38/72 (52%)
Query: 423 DTLKHLQLVFKTHAREKMGVLRVERLRDALKDVGFIVPERVISLLVFRYMRKDGMLRFGD 482
+ +K Q ++K ++ G + L A + GF + E + ++++ RY + G + F +
Sbjct: 169 NNIKRWQAIYKQFDTDRSGTICSSELPGAFEAAGFHLNEHLYNMIIRRYSDESGNMDFDN 228
Query: 483 FVSAVMHLHRVF 494
F+S ++ L +F
Sbjct: 229 FISCLVRLDAMF 240
>BC128605-1|AAI28606.1| 156|Homo sapiens calpain 3, (p94) protein.
Length = 156
Score = 38.7 bits (86), Expect = 0.048
Identities = 18/76 (23%), Positives = 37/76 (48%)
Query: 425 LKHLQLVFKTHAREKMGVLRVERLRDALKDVGFIVPERVISLLVFRYMRKDGMLRFGDFV 484
+K Q +FK + ++ G + +R+A+ D GF + ++ ++ RY K + F F+
Sbjct: 59 IKAWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDIITMRYADKHMNIDFDSFI 118
Query: 485 SAVMHLHRVFVQVYDF 500
+ L +F + F
Sbjct: 119 CCFVRLEGMFRAFHAF 134
>BC107791-1|AAI07792.1| 156|Homo sapiens CAPN3 protein protein.
Length = 156
Score = 38.7 bits (86), Expect = 0.048
Identities = 18/76 (23%), Positives = 37/76 (48%)
Query: 425 LKHLQLVFKTHAREKMGVLRVERLRDALKDVGFIVPERVISLLVFRYMRKDGMLRFGDFV 484
+K Q +FK + ++ G + +R+A+ D GF + ++ ++ RY K + F F+
Sbjct: 59 IKAWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDIITMRYADKHMNIDFDSFI 118
Query: 485 SAVMHLHRVFVQVYDF 500
+ L +F + F
Sbjct: 119 CCFVRLEGMFRAFHAF 134
>BC100783-1|AAI00784.1| 174|Homo sapiens CAPN3 protein protein.
Length = 174
Score = 38.7 bits (86), Expect = 0.048
Identities = 18/76 (23%), Positives = 37/76 (48%)
Query: 425 LKHLQLVFKTHAREKMGVLRVERLRDALKDVGFIVPERVISLLVFRYMRKDGMLRFGDFV 484
+K Q +FK + ++ G + +R+A+ D GF + ++ ++ RY K + F F+
Sbjct: 59 IKAWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDIITMRYADKHMNIDFDSFI 118
Query: 485 SAVMHLHRVFVQVYDF 500
+ L +F + F
Sbjct: 119 CCFVRLEGMFRAFHAF 134
>BC100782-1|AAI00783.1| 156|Homo sapiens calpain 3, (p94) protein.
Length = 156
Score = 38.7 bits (86), Expect = 0.048
Identities = 18/76 (23%), Positives = 37/76 (48%)
Query: 425 LKHLQLVFKTHAREKMGVLRVERLRDALKDVGFIVPERVISLLVFRYMRKDGMLRFGDFV 484
+K Q +FK + ++ G + +R+A+ D GF + ++ ++ RY K + F F+
Sbjct: 59 IKAWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDIITMRYADKHMNIDFDSFI 118
Query: 485 SAVMHLHRVFVQVYDF 500
+ L +F + F
Sbjct: 119 CCFVRLEGMFRAFHAF 134
>BC067126-1|AAH67126.1| 156|Homo sapiens calpain 3, (p94) protein.
Length = 156
Score = 38.7 bits (86), Expect = 0.048
Identities = 18/76 (23%), Positives = 37/76 (48%)
Query: 425 LKHLQLVFKTHAREKMGVLRVERLRDALKDVGFIVPERVISLLVFRYMRKDGMLRFGDFV 484
+K Q +FK + ++ G + +R+A+ D GF + ++ ++ RY K + F F+
Sbjct: 59 IKAWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDIITMRYADKHMNIDFDSFI 118
Query: 485 SAVMHLHRVFVQVYDF 500
+ L +F + F
Sbjct: 119 CCFVRLEGMFRAFHAF 134
>BC007810-1|AAH07810.3| 156|Homo sapiens calpain 3, (p94) protein.
Length = 156
Score = 38.7 bits (86), Expect = 0.048
Identities = 18/76 (23%), Positives = 37/76 (48%)
Query: 425 LKHLQLVFKTHAREKMGVLRVERLRDALKDVGFIVPERVISLLVFRYMRKDGMLRFGDFV 484
+K Q +FK + ++ G + +R+A+ D GF + ++ ++ RY K + F F+
Sbjct: 59 IKAWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDIITMRYADKHMNIDFDSFI 118
Query: 485 SAVMHLHRVFVQVYDF 500
+ L +F + F
Sbjct: 119 CCFVRLEGMFRAFHAF 134
>BC004883-1|AAH04883.1| 156|Homo sapiens calpain 3, (p94) protein.
Length = 156
Score = 38.7 bits (86), Expect = 0.048
Identities = 18/76 (23%), Positives = 37/76 (48%)
Query: 425 LKHLQLVFKTHAREKMGVLRVERLRDALKDVGFIVPERVISLLVFRYMRKDGMLRFGDFV 484
+K Q +FK + ++ G + +R+A+ D GF + ++ ++ RY K + F F+
Sbjct: 59 IKAWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDIITMRYADKHMNIDFDSFI 118
Query: 485 SAVMHLHRVFVQVYDF 500
+ L +F + F
Sbjct: 119 CCFVRLEGMFRAFHAF 134
>BC003521-1|AAH03521.1| 156|Homo sapiens calpain 3, (p94) protein.
Length = 156
Score = 38.7 bits (86), Expect = 0.048
Identities = 18/76 (23%), Positives = 37/76 (48%)
Query: 425 LKHLQLVFKTHAREKMGVLRVERLRDALKDVGFIVPERVISLLVFRYMRKDGMLRFGDFV 484
+K Q +FK + ++ G + +R+A+ D GF + ++ ++ RY K + F F+
Sbjct: 59 IKAWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDIITMRYADKHMNIDFDSFI 118
Query: 485 SAVMHLHRVFVQVYDF 500
+ L +F + F
Sbjct: 119 CCFVRLEGMFRAFHAF 134
>BC100784-1|AAI00785.1| 156|Homo sapiens calpain 3, (p94) protein.
Length = 156
Score = 38.3 bits (85), Expect = 0.064
Identities = 17/70 (24%), Positives = 35/70 (50%)
Query: 425 LKHLQLVFKTHAREKMGVLRVERLRDALKDVGFIVPERVISLLVFRYMRKDGMLRFGDFV 484
+K Q +FK + ++ G + +R+A+ D GF + ++ ++ RY K + F F+
Sbjct: 59 IKAWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDIITMRYADKHMNIDFDSFI 118
Query: 485 SAVMHLHRVF 494
+ L +F
Sbjct: 119 CCFVRLEGMF 128
>AK074418-1|BAB85075.1| 423|Homo sapiens protein ( Homo sapiens
cDNA FLJ23838 fis, clone KAT02256. ).
Length = 423
Score = 34.7 bits (76), Expect = 0.78
Identities = 16/29 (55%), Positives = 19/29 (65%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESI 77
+L GSY L YG L D L DLTGG+ +I
Sbjct: 175 KLLGSYSDLHYGFLEDALVDLTGGVITNI 203
>AC092569-1|AAX82015.1| 423|Homo sapiens unknown protein.
Length = 423
Score = 34.7 bits (76), Expect = 0.78
Identities = 16/29 (55%), Positives = 19/29 (65%)
Query: 49 RLHGSYEALKYGSLLDGLADLTGGITESI 77
+L GSY L YG L D L DLTGG+ +I
Sbjct: 175 KLLGSYSDLHYGFLEDALVDLTGGVITNI 203
>AF089096-1|AAG17974.1| 138|Homo sapiens calpain-like protease
CAPN10h protein.
Length = 138
Score = 33.5 bits (73), Expect = 1.8
Identities = 13/34 (38%), Positives = 23/34 (67%)
Query: 314 SRQVSQRCQLESGAYLIMPTTFEPREEAQFTLRI 347
+++VS+ C L +G Y ++P+T+ P E FT+ I
Sbjct: 75 AQEVSRLCLLPAGTYKVVPSTYLPDTEGAFTVTI 108
>CR848842-2|CAM45846.1| 156|Homo sapiens calpain 8 (nCL-2) protein.
Length = 156
Score = 32.7 bits (71), Expect = 3.2
Identities = 17/69 (24%), Positives = 33/69 (47%), Gaps = 1/69 (1%)
Query: 426 KHLQLVFKTHAREKMGVLRVERLRDALKDVGFIVPERVISLLVFRYMRKDGMLRFGDFVS 485
K+L++ ++T G + +R AL+ GF + +V + RY + F FV+
Sbjct: 62 KYLEIYWETDYNHS-GTIDAHEMRTALRKAGFTLNSQVQQTIALRYACSKLGINFDSFVA 120
Query: 486 AVMHLHRVF 494
++ L +F
Sbjct: 121 CMIRLETLF 129
>AB058743-1|BAB47469.2| 2443|Homo sapiens KIAA1840 protein protein.
Length = 2443
Score = 31.9 bits (69), Expect = 5.5
Identities = 30/112 (26%), Positives = 46/112 (41%), Gaps = 12/112 (10%)
Query: 98 VTAHYFPPVTIISVFFLSLPTGIRLVKIRLRRSVINIF-QVDTTNEPVYLIRLRRP---- 152
+++ + P + V FL L G+ +K+R+ V NI NE +R
Sbjct: 1242 LSSFHIPSIGAACVCFLEL-LGLDSLKLRVDMKVANIILSYKCRNEDAQYSFIRESVAEK 1300
Query: 153 ---LGHGETPISH---IVLDTALWKTIPQYERDRLMTASKGVWMLFSDFQRL 198
L GE + ++L+ W +I Q E RL + S W L F RL
Sbjct: 1301 LSKLADGEKTTTEELLVLLEEGTWNSIQQQEIKRLSSESSSQWALVVQFCRL 1352
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.325 0.139 0.415
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 72,488,105
Number of Sequences: 224733
Number of extensions: 2962567
Number of successful extensions: 12627
Number of sequences better than 10.0: 94
Number of HSP's better than 10.0 without gapping: 92
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 12248
Number of HSP's gapped (non-prelim): 229
length of query: 510
length of database: 73,234,838
effective HSP length: 93
effective length of query: 417
effective length of database: 52,334,669
effective search space: 21823556973
effective search space used: 21823556973
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 40 (21.6 bits)
S2: 67 (31.1 bits)
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