Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA002094-TA|BGIBMGA002094-PA|IPR000719|Protein kinase,
IPR011009|Protein kinase-like, IPR008271|Serine/threonine protein
kinase, active site, IPR002290|Serine/threonine protein kinase
(715 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC132833-1|AAI32834.1| 388|Homo sapiens hypothetical protein LO... 137 1e-31
BC132831-1|AAI32832.1| 388|Homo sapiens hypothetical protein LO... 137 1e-31
AL139092-1|CAH73662.1| 388|Homo sapiens protein ( Human DNA seq... 137 1e-31
AL138876-2|CAI12221.2| 388|Homo sapiens protein ( Human DNA seq... 137 1e-31
X90870-1|CAA62378.1| 458|Homo sapiens myosin-light-chain kinase... 136 2e-31
U48959-1|AAC18423.2| 1914|Homo sapiens myosin light chain kinase... 136 2e-31
AY339601-1|AAQ02673.1| 1914|Homo sapiens long myosin light chain... 136 2e-31
AF069601-1|AAD15921.2| 1845|Homo sapiens myosin light chain kina... 136 2e-31
AB037663-1|BAB21504.1| 992|Homo sapiens myosin light chain kina... 136 2e-31
AY424270-1|AAR29062.1| 1914|Homo sapiens myosin lignt chain poly... 135 6e-31
AY424269-1|AAR29061.1| 1845|Homo sapiens myosin light chain poly... 135 6e-31
X85337-1|CAA59685.1| 991|Homo sapiens myosin light chain kinase... 131 7e-30
BC047696-1|AAH47696.1| 414|Homo sapiens serine/threonine kinase... 130 2e-29
BC023508-1|AAH23508.2| 414|Homo sapiens serine/threonine kinase... 130 2e-29
AB011420-1|BAA34126.1| 414|Homo sapiens DRAK1 protein. 130 2e-29
BC032787-1|AAH32787.1| 476|Homo sapiens calcium/calmodulin-depe... 130 2e-29
AY212935-1|AAP29964.1| 460|Homo sapiens CLICK III protein. 130 2e-29
AL049688-1|CAB41259.1| 481|Homo sapiens hypothetical protein pr... 130 2e-29
AL023754-3|CAI19991.1| 476|Homo sapiens calcium/calmodulin-depe... 130 2e-29
AF428261-1|AAL28100.1| 476|Homo sapiens calcium/calmodulin-depe... 130 2e-29
CR542225-1|CAG47021.1| 372|Homo sapiens STK17B protein. 125 6e-28
BC016040-1|AAH16040.1| 372|Homo sapiens serine/threonine kinase... 124 8e-28
AC114760-2|AAY14982.1| 372|Homo sapiens unknown protein. 124 8e-28
AB011421-1|BAA34127.1| 372|Homo sapiens DRAK2 protein. 124 8e-28
BC109097-1|AAI09098.2| 795|Homo sapiens MLCK protein protein. 124 1e-27
AJ247087-1|CAC42766.1| 795|Homo sapiens myosin light chain kina... 124 1e-27
CR542210-1|CAG47006.1| 372|Homo sapiens STK17B protein. 122 6e-27
BC126432-1|AAI26433.1| 454|Homo sapiens death-associated protei... 121 8e-27
BC126430-1|AAI26431.1| 454|Homo sapiens death-associated protei... 121 8e-27
AB022341-1|BAA81746.1| 454|Homo sapiens ZIP kinase protein. 121 8e-27
AB007144-1|BAA24955.1| 454|Homo sapiens ZIP-kinase protein. 121 8e-27
L41816-1|AAA99458.1| 370|Homo sapiens cam kinase I protein. 120 2e-26
BC106755-1|AAI06756.1| 370|Homo sapiens calcium/calmodulin-depe... 120 2e-26
BC106754-1|AAI06755.1| 370|Homo sapiens calcium/calmodulin-depe... 120 2e-26
X90568-1|CAA62188.1|26926|Homo sapiens titin protein. 117 1e-25
X69490-1|CAA49245.1| 4650|Homo sapiens titin protein. 117 1e-25
X64697-1|CAA45938.1| 3100|Homo sapiens titin protein. 117 1e-25
BC035745-1|AAH35745.1| 385|Homo sapiens calcium/calmodulin-depe... 117 1e-25
AL731559-2|CAI14675.1| 385|Homo sapiens calcium/calmodulin-depe... 117 1e-25
AL731559-1|CAI14674.1| 357|Homo sapiens calcium/calmodulin-depe... 117 1e-25
AL512783-2|CAH74036.1| 385|Homo sapiens calcium/calmodulin-depe... 117 1e-25
AL512783-1|CAH74035.1| 357|Homo sapiens calcium/calmodulin-depe... 117 1e-25
AL512284-2|CAH71694.1| 385|Homo sapiens calcium/calmodulin-depe... 117 1e-25
AL512284-1|CAH71693.1| 357|Homo sapiens calcium/calmodulin-depe... 117 1e-25
AL391314-2|CAI14410.1| 385|Homo sapiens calcium/calmodulin-depe... 117 1e-25
AL391314-1|CAI14409.1| 357|Homo sapiens calcium/calmodulin-depe... 117 1e-25
AJ277892-1|CAD12455.1|26926|Homo sapiens N2B-Titin Isoform protein. 117 1e-25
AF286366-1|AAG00534.1| 357|Homo sapiens CamKI-like protein kina... 117 1e-25
AB081726-1|BAC19846.1| 385|Homo sapiens CaM-kinase I delta prot... 117 1e-25
X76104-1|CAA53712.1| 1431|Homo sapiens DAP-kinase protein. 117 2e-25
DQ436495-1|ABD96827.1| 1430|Homo sapiens death-associated protei... 117 2e-25
BT006935-1|AAP35581.1| 367|Homo sapiens death-associated protei... 117 2e-25
BC113660-1|AAI13661.1| 1430|Homo sapiens death-associated protei... 117 2e-25
AL591852-1|CAH71696.1| 1455|Homo sapiens death-associated protei... 117 2e-25
AL161787-1|CAH73544.1| 1455|Homo sapiens death-associated protei... 117 2e-25
AL160279-1|CAI16306.1| 1455|Homo sapiens death-associated protei... 117 2e-25
AB208871-1|BAD92108.1| 1433|Homo sapiens Hypothetical protein DK... 117 2e-25
BC062616-1|AAH62616.1| 424|Homo sapiens protein serine kinase H... 116 4e-25
AJ272212-1|CAB91984.1| 424|Homo sapiens protein serine kinase p... 116 4e-25
L07597-1|AAC82497.1| 735|Homo sapiens ribosomal protein S6 kina... 115 7e-25
BC014966-1|AAH14966.1| 735|Homo sapiens ribosomal protein S6 ki... 115 7e-25
AL627313-6|CAI14649.1| 735|Homo sapiens ribosomal protein S6 ki... 115 7e-25
AL627313-4|CAI14647.1| 578|Homo sapiens ribosomal protein S6 ki... 115 7e-25
BC127622-1|AAI27623.1| 596|Homo sapiens myosin light chain kina... 114 9e-25
BC092413-1|AAH92413.1| 596|Homo sapiens myosin light chain kina... 114 9e-25
BC069627-1|AAH69627.1| 596|Homo sapiens skeletal myosin light c... 114 9e-25
AL160175-10|CAC10006.1| 596|Homo sapiens myosin light chain kin... 114 9e-25
AJ272502-1|CAC81354.1| 596|Homo sapiens skeletal muscle-specifi... 114 9e-25
AF325549-1|AAK15494.1| 596|Homo sapiens skeletal myosin light c... 114 9e-25
BC114506-1|AAI14507.1| 370|Homo sapiens death-associated protei... 113 2e-24
AF052941-1|AAC35001.1| 370|Homo sapiens DAP-kinase related prot... 113 2e-24
AB018001-1|BAA88063.1| 370|Homo sapiens Death-associated protei... 113 2e-24
CR456418-1|CAG30304.1| 586|Homo sapiens CHEK2 protein. 112 5e-24
BC004207-1|AAH04207.1| 543|Homo sapiens CHK2 checkpoint homolog... 112 5e-24
AY800241-1|AAV41895.1| 543|Homo sapiens CHK2 checkpoint homolog... 112 5e-24
AY551303-1|AAS58464.1| 452|Homo sapiens protein kinase Chk2 tra... 112 5e-24
AY551297-1|AAS58458.1| 586|Homo sapiens protein kinase Chk2 tra... 112 5e-24
AL121825-1|CAH73823.1| 543|Homo sapiens CHK2 checkpoint homolog... 112 5e-24
AL117330-1|CAH73875.1| 543|Homo sapiens CHK2 checkpoint homolog... 112 5e-24
AJ131197-1|CAA10319.1| 543|Homo sapiens protein kinase protein. 112 5e-24
AF174135-1|AAD48504.1| 543|Homo sapiens protein kinase CHK2 pro... 112 5e-24
AF096279-1|AAD11784.1| 543|Homo sapiens HuCds1 kinase protein. 112 5e-24
AF086904-1|AAC83693.1| 543|Homo sapiens protein kinase Chk2 pro... 112 5e-24
Z98049-1|CAI20579.1| 733|Homo sapiens ribosomal protein S6 kina... 111 1e-23
X85106-1|CAA59427.1| 733|Homo sapiens ribosomal S6 kinase protein. 111 1e-23
BC002363-1|AAH02363.1| 733|Homo sapiens ribosomal protein S6 ki... 111 1e-23
AL022069-2|CAI19651.1| 733|Homo sapiens ribosomal protein S6 ki... 111 1e-23
AB209116-1|BAD92353.1| 806|Homo sapiens ribosomal protein S6 ki... 111 1e-23
AF217975-1|AAG17218.1| 322|Homo sapiens unknown protein. 110 1e-23
U08316-1|AAA81952.1| 740|Homo sapiens insulin-stimulated protei... 110 2e-23
L24959-1|AAA18251.1| 473|Homo sapiens calcium/calmodulin depend... 110 2e-23
L17000-1|AAA35639.1| 473|Homo sapiens calcium/calmodulin-depend... 110 2e-23
D30742-1|BAA06403.1| 473|Homo sapiens calmodulin-dependent prot... 110 2e-23
BC096303-1|AAH96303.1| 740|Homo sapiens ribosomal protein S6 ki... 110 2e-23
BC096302-1|AAH96302.1| 740|Homo sapiens ribosomal protein S6 ki... 110 2e-23
BC096301-1|AAH96301.1| 740|Homo sapiens ribosomal protein S6 ki... 110 2e-23
BC025687-1|AAH25687.1| 473|Homo sapiens calcium/calmodulin-depe... 110 2e-23
BC016695-1|AAH16695.2| 503|Homo sapiens CAMK4 protein protein. 110 2e-23
AL807772-3|CAI39687.1| 740|Homo sapiens ribosomal protein S6 ki... 110 2e-23
AL732366-2|CAI40548.1| 740|Homo sapiens ribosomal protein S6 ki... 110 2e-23
AL670729-4|CAH71670.2| 2582|Homo sapiens obscurin, cytoskeletal ... 110 2e-23
AL353593-4|CAM27610.1| 2582|Homo sapiens obscurin, cytoskeletal ... 110 2e-23
AB208933-1|BAD92170.1| 806|Homo sapiens ribosomal protein S6 ki... 110 2e-23
AB102662-1|BAC81131.1| 726|Homo sapiens RPS6KA3 protein. 110 2e-23
AB046859-1|BAB13465.2| 2584|Homo sapiens KIAA1639 protein protein. 110 2e-23
AF069604-1|AAD15924.1| 560|Homo sapiens myosin light chain kina... 109 3e-23
AF069603-1|AAD15923.1| 1793|Homo sapiens myosin light chain kina... 109 3e-23
AF069602-1|AAD15922.1| 1862|Homo sapiens myosin light chain kina... 109 3e-23
AF080000-1|AAD23915.1| 802|Homo sapiens RSK-like protein kinase... 109 4e-23
AF074393-1|AAC31171.1| 802|Homo sapiens nuclear mitogen- and st... 109 4e-23
AM231061-1|CAJ76912.1| 1960|Homo sapiens obscurin isoform B prot... 108 8e-23
BC040457-1|AAH40457.1| 478|Homo sapiens calcium/calmodulin-depe... 105 4e-22
AF090421-1|AAC69577.1| 809|Homo sapiens ribosome S6 protein kin... 105 7e-22
AF145711-1|AAD30559.1| 489|Homo sapiens calcium/calmodulin-depe... 104 1e-21
AF145710-1|AAD30558.1| 478|Homo sapiens calcium/calmodulin-depe... 104 1e-21
AF091486-1|AAD55815.1| 478|Homo sapiens calmodulin-dependent pr... 104 1e-21
AB023185-1|BAA76812.1| 527|Homo sapiens KIAA0968 protein protein. 104 1e-21
AB011422-1|BAA76314.1| 1289|Homo sapiens Trad protein. 104 1e-21
CR536566-1|CAG38803.1| 745|Homo sapiens RPS6KA6 protein. 103 2e-21
AL389887-1|CAC16111.2| 745|Homo sapiens ribosomal protein S6 ki... 103 2e-21
AL354653-1|CAD13486.2| 745|Homo sapiens ribosomal protein S6 ki... 103 2e-21
AF184965-1|AAF13190.1| 745|Homo sapiens ribosomal S6 kinase pro... 103 2e-21
X97630-1|CAA66229.1| 745|Homo sapiens serine/threonine protein ... 103 2e-21
BT007342-1|AAP36006.1| 755|Homo sapiens MAP/microtubule affinit... 103 2e-21
BC084540-1|AAH84540.1| 724|Homo sapiens MAP/microtubule affinit... 103 2e-21
BC008771-1|AAH08771.2| 778|Homo sapiens MARK2 protein protein. 103 2e-21
AF387638-1|AAK82368.1| 691|Homo sapiens Ser/Thr protein kinase ... 103 2e-21
AB188493-1|BAD37141.1| 719|Homo sapiens serine/threonine kinase... 103 2e-21
AB051552-1|BAB21856.1| 608|Homo sapiens KIAA1765 protein protein. 103 2e-21
BC007753-1|AAH07753.1| 242|Homo sapiens Unknown (protein for IM... 103 3e-21
L07598-1|AAC82496.1| 540|Homo sapiens ribosomal protein S6 kina... 100 2e-20
BC032784-1|AAH32784.1| 478|Homo sapiens calcium/calmodulin-depe... 100 2e-20
AB209288-1|BAD92525.1| 522|Homo sapiens calcium/calmodulin-depe... 100 2e-20
AY987011-1|AAX88806.1| 489|Homo sapiens calcium/calmodulin-depe... 100 2e-20
D79997-1|BAA11492.2| 656|Homo sapiens KIAA0175 protein. 100 4e-20
BC014039-1|AAH14039.1| 651|Homo sapiens maternal embryonic leuc... 100 4e-20
AL442063-1|CAI16995.2| 651|Homo sapiens maternal embryonic leuc... 100 4e-20
AL354932-1|CAI11034.2| 651|Homo sapiens maternal embryonic leuc... 100 4e-20
AK222811-1|BAD96531.1| 651|Homo sapiens maternal embryonic leuc... 100 4e-20
AF071569-1|AAD20442.1| 499|Homo sapiens multifunctional calcium... 99 5e-20
AL834498-1|CAD39156.1| 716|Homo sapiens hypothetical protein pr... 99 6e-20
AC093748-1|AAY40983.1| 443|Homo sapiens unknown protein. 99 6e-20
AB209181-1|BAD92418.1| 796|Homo sapiens Hypothetical protein DK... 99 6e-20
AL136373-4|CAI14764.1| 424|Homo sapiens MAP kinase interacting ... 98 8e-20
AB000409-1|BAA19885.1| 424|Homo sapiens MNK1 protein. 98 8e-20
U66064-1|AAB80848.1| 315|Homo sapiens calcium/calmodulin-depend... 98 1e-19
BC069823-1|AAH69823.1| 552|Homo sapiens AMP-activated protein k... 98 1e-19
BC069740-1|AAH69740.1| 552|Homo sapiens AMP-activated protein k... 98 1e-19
BC069680-1|AAH69680.1| 552|Homo sapiens protein kinase, AMP-act... 98 1e-19
AL713896-5|CAI13788.1| 516|Homo sapiens calcium/calmodulin-depe... 98 1e-19
AL713896-4|CAI13789.1| 495|Homo sapiens calcium/calmodulin-depe... 98 1e-19
AL713896-3|CAI13790.1| 529|Homo sapiens calcium/calmodulin-depe... 98 1e-19
AL713896-2|CAI13791.1| 527|Homo sapiens calcium/calmodulin-depe... 98 1e-19
AL596247-5|CAI13967.1| 516|Homo sapiens calcium/calmodulin-depe... 98 1e-19
AL596247-4|CAI13966.1| 495|Homo sapiens calcium/calmodulin-depe... 98 1e-19
AL596247-3|CAI13965.1| 529|Homo sapiens calcium/calmodulin-depe... 98 1e-19
AL596247-2|CAI13968.1| 527|Homo sapiens calcium/calmodulin-depe... 98 1e-19
AL035705-2|CAC17574.2| 552|Homo sapiens protein kinase, AMP-act... 98 1e-19
U06454-1|AAA64745.1| 552|Homo sapiens AMP-activated protein kin... 97 1e-19
EF056019-1|ABK30810.1| 552|Homo sapiens AMP-activated alpha 2 s... 97 1e-19
BC126182-1|AAI26183.1| 385|Homo sapiens protein serine kinase H... 97 1e-19
BC126180-1|AAI26181.1| 385|Homo sapiens protein serine kinase H... 97 1e-19
BC022558-1|AAH22558.1| 344|Homo sapiens CAMK2D protein protein. 97 1e-19
AY355461-1|AAQ84219.1| 347|Homo sapiens MNK1-like kinase 1b pro... 97 1e-19
AY037806-1|AAK59985.1| 385|Homo sapiens serine/threonine kinase... 97 1e-19
BC034044-1|AAH34044.1| 527|Homo sapiens calcium/calmodulin-depe... 97 2e-19
U12779-1|AAA20851.1| 370|Homo sapiens MAP kinase activated prot... 96 4e-19
BC114478-1|AAI14479.1| 795|Homo sapiens MARK1 protein protein. 96 4e-19
BC113869-1|AAI13870.1| 795|Homo sapiens MARK1 protein protein. 96 4e-19
BC052584-1|AAH52584.1| 400|Homo sapiens mitogen-activated prote... 96 4e-19
BC037303-1|AAH37303.1| 550|Homo sapiens PRKAA1 protein protein. 96 4e-19
BC036060-1|AAH36060.2| 400|Homo sapiens mitogen-activated prote... 96 4e-19
AL592406-3|CAH72463.1| 795|Homo sapiens MAP/microtubule affinit... 96 4e-19
AL591846-12|CAI13544.1| 400|Homo sapiens mitogen-activated prot... 96 4e-19
AL591846-11|CAI13543.1| 370|Homo sapiens mitogen-activated prot... 96 4e-19
AF154845-1|AAF72103.1| 795|Homo sapiens MARK protein. 96 4e-19
BC017306-1|AAH17306.1| 628|Homo sapiens NUAK family, SNF1-like ... 95 6e-19
AK074830-1|BAC11234.1| 628|Homo sapiens protein ( Homo sapiens ... 95 6e-19
AJ271722-1|CAB71146.1| 714|Homo sapiens putative serine/threoni... 95 6e-19
AB019245-1|BAA37145.1| 481|Homo sapiens S6 kinase b protein. 95 8e-19
U64205-1|AAC15093.1| 729|Homo sapiens Cdc25C associated protein... 95 1e-18
M80359-1|AAA59991.1| 713|Homo sapiens protein p78 protein. 95 1e-18
BC024773-1|AAH24773.1| 729|Homo sapiens MAP/microtubule affinit... 95 1e-18
BC006106-1|AAH06106.3| 482|Homo sapiens ribosomal protein S6 ki... 95 1e-18
BC000094-1|AAH00094.3| 482|Homo sapiens ribosomal protein S6 ki... 95 1e-18
AF465413-1|AAL69982.1| 753|Homo sapiens MAP/microtubule affinit... 95 1e-18
AF387637-1|AAK82367.1| 744|Homo sapiens Ser/Thr protein kinase ... 95 1e-18
AF099739-1|AAD20990.1| 482|Homo sapiens S6 kinase-related kinas... 95 1e-18
AF076931-1|AAD46063.1| 482|Homo sapiens serine/threonine kinase... 95 1e-18
AB016869-1|BAA34402.1| 495|Homo sapiens p70 ribosomal S6 kinase... 95 1e-18
AY603755-1|AAT80901.1| 3094|Homo sapiens striated muscle prefere... 94 1e-18
AB037718-1|BAA92535.1| 2242|Homo sapiens KIAA1297 protein protein. 94 1e-18
AB022017-1|BAA36547.1| 550|Homo sapiens AMP-activated protein k... 94 1e-18
D43636-1|BAA07744.2| 766|Homo sapiens KIAA0096 protein. 94 2e-18
AF415197-1|AAM33514.1| 566|Homo sapiens calcium/calmodulin-depe... 94 2e-18
BC020479-1|AAH20479.1| 466|Homo sapiens AKT3 protein protein. 93 3e-18
AY005799-1|AAF91073.1| 465|Homo sapiens protein kinase B gamma ... 93 3e-18
AL662889-3|CAH73073.1| 479|Homo sapiens v-akt murine thymoma vi... 93 3e-18
AL662889-2|CAH73072.1| 465|Homo sapiens v-akt murine thymoma vi... 93 3e-18
AL592151-2|CAH72892.1| 479|Homo sapiens v-akt murine thymoma vi... 93 3e-18
AL592151-1|CAH72891.1| 465|Homo sapiens v-akt murine thymoma vi... 93 3e-18
AL591721-2|CAH71867.1| 479|Homo sapiens v-akt murine thymoma vi... 93 3e-18
AL591721-1|CAH71866.1| 465|Homo sapiens v-akt murine thymoma vi... 93 3e-18
AL023754-2|CAI19990.1| 245|Homo sapiens calcium/calmodulin-depe... 93 3e-18
AJ245709-1|CAB53537.1| 479|Homo sapiens Akt-3 protein protein. 93 3e-18
AJ010119-1|CAA09009.1| 772|Homo sapiens Ribosomal protein kinas... 93 3e-18
AF135794-1|AAD24196.1| 479|Homo sapiens AKT3 protein kinase pro... 93 3e-18
AF124141-1|AAD29089.1| 479|Homo sapiens protein kinase B gamma ... 93 3e-18
AF085234-1|AAL40392.1| 479|Homo sapiens STK-2 protein. 93 3e-18
AF074715-1|AAC67395.1| 705|Homo sapiens mitogen- and stress-act... 93 3e-18
L07599-1|AAC82495.1| 580|Homo sapiens ribosomal protein S6 kina... 93 4e-18
BC071567-1|AAH71567.1| 765|Homo sapiens SNRK protein protein. 93 4e-18
BC021269-1|AAH21269.2| 453|Homo sapiens CAMK2G protein protein. 93 4e-18
AL713896-1|CAI13787.1| 453|Homo sapiens calcium/calmodulin-depe... 93 4e-18
AL596247-1|CAI13964.1| 453|Homo sapiens calcium/calmodulin-depe... 93 4e-18
M34181-1|AAA60170.1| 351|Homo sapiens cAMP-dependent protein ki... 92 5e-18
DQ667174-1|ABG25919.1| 398|Homo sapiens protein kinase, cAMP-de... 92 5e-18
BC121154-1|AAI21155.1| 465|Homo sapiens v-akt murine thymoma vi... 92 5e-18
BC016285-1|AAH16285.1| 257|Homo sapiens protein kinase, cAMP-de... 92 5e-18
AY120867-1|AAM55491.1| 752|Homo sapiens MAP/microtubule affinit... 92 5e-18
AY057448-1|AAL23683.1| 752|Homo sapiens MARK4 serine/threonine ... 92 5e-18
AL450063-11|CAI16854.1| 264|Homo sapiens protein kinase, cAMP-d... 92 5e-18
AL450063-7|CAI16850.1| 245|Homo sapiens protein kinase, cAMP-de... 92 5e-18
AL450063-3|CAI16846.1| 398|Homo sapiens protein kinase, cAMP-de... 92 5e-18
AL450063-2|CAI16845.1| 351|Homo sapiens protein kinase, cAMP-de... 92 5e-18
AL450063-1|CAI16844.1| 257|Homo sapiens protein kinase, cAMP-de... 92 5e-18
AL359504-2|CAI14541.1| 351|Homo sapiens protein kinase, cAMP-de... 92 5e-18
AL359504-1|CAI14540.1| 257|Homo sapiens protein kinase, cAMP-de... 92 5e-18
AK075272-1|BAC11510.1| 752|Homo sapiens protein ( Homo sapiens ... 92 5e-18
AB209189-1|BAD92426.1| 365|Homo sapiens cAMP-dependent protein ... 92 5e-18
AB058763-1|BAB47489.1| 689|Homo sapiens KIAA1860 protein protein. 92 5e-18
AB011109-1|BAA25463.2| 698|Homo sapiens KIAA0537 protein protein. 92 5e-18
U23460-1|AAC99802.1| 664|Homo sapiens proline rich calmodulin-d... 91 9e-18
L07043-1|AAB61379.1| 306|Homo sapiens calcium/calmodulin-depend... 91 9e-18
BC019070-1|AAH19070.1| 503|Homo sapiens calcium/calmodulin-depe... 91 9e-18
AK222703-1|BAD96423.1| 542|Homo sapiens calcium/calmodulin-depe... 91 9e-18
AJ252238-1|CAB65122.1| 518|Homo sapiens calcium/calmodulin depe... 91 9e-18
AJ252237-1|CAB65121.1| 479|Homo sapiens calcium/calmodulin depe... 91 9e-18
AJ252236-1|CAB65120.1| 503|Homo sapiens calcium/calmodulin depe... 91 9e-18
AF140350-1|AAD42070.1| 449|Homo sapiens calcium/calmodulin-depe... 91 9e-18
AF083419-1|AAD42038.1| 517|Homo sapiens calcium/calmodulin-depe... 91 9e-18
AF081924-1|AAD42037.1| 492|Homo sapiens calcium/calmodulin-depe... 91 9e-18
AF081572-1|AAD42036.1| 503|Homo sapiens calcium/calmodulin-depe... 91 9e-18
AF078803-1|AAD42035.1| 542|Homo sapiens calcium/calmodulin-depe... 91 9e-18
M95936-1|AAA58364.1| 481|Homo sapiens protein serine/threonine ... 91 1e-17
M77198-1|AAA36585.1| 520|Homo sapiens rac protein kinase-beta p... 91 1e-17
BC120994-1|AAI20995.1| 481|Homo sapiens v-akt murine thymoma vi... 91 1e-17
AF112472-1|AAD03744.1| 542|Homo sapiens calcium/calmodulin-depe... 91 1e-17
AF112471-1|AAD03743.1| 517|Homo sapiens calcium/calmodulin-depe... 91 1e-17
Y11950-1|CAA72694.1| 406|Homo sapiens phosphorylase kinase gamm... 90 2e-17
U43784-1|AAC50428.1| 382|Homo sapiens mitogen activated protein... 90 2e-17
U09578-1|AAD09136.1| 382|Homo sapiens MAPKAP kinase protein. 90 2e-17
M31606-1|AAA36442.1| 406|Homo sapiens phosphorylase kinase prot... 90 2e-17
BC032709-1|AAH32709.1| 344|Homo sapiens Unknown (protein for IM... 90 2e-17
BC010407-1|AAH10407.1| 382|Homo sapiens mitogen-activated prote... 90 2e-17
BC007591-1|AAH07591.1| 382|Homo sapiens mitogen-activated prote... 90 2e-17
BC002541-1|AAH02541.1| 406|Homo sapiens phosphorylase kinase, g... 90 2e-17
BC001662-1|AAH01662.1| 382|Homo sapiens mitogen-activated prote... 90 2e-17
AK223561-1|BAD97281.1| 765|Homo sapiens ribosomal protein S6 ki... 90 2e-17
AB088047-1|BAC03375.1| 752|Homo sapiens microtubule affinity-re... 90 2e-17
AB049127-1|BAB39380.1| 688|Homo sapiens MAP/microtubule affinit... 90 2e-17
U42390-1|AAC34245.1| 2861|Homo sapiens Trio protein. 90 3e-17
BC017268-1|AAH17268.1| 383|Homo sapiens TRIO protein protein. 90 3e-17
AK131423-1|BAD18570.1| 596|Homo sapiens protein ( Homo sapiens ... 90 3e-17
AF226044-1|AAF86944.1| 765|Homo sapiens HSNFRK protein. 90 3e-17
AF091395-1|AAC43042.1| 3038|Homo sapiens Trio isoform protein. 90 3e-17
BC015472-1|AAH15472.1| 363|Homo sapiens PRKD2 protein protein. 89 4e-17
AK075266-1|BAC11508.1| 721|Homo sapiens protein ( Homo sapiens ... 89 4e-17
AK074673-1|BAC11127.1| 721|Homo sapiens protein ( Homo sapiens ... 89 4e-17
AF309082-1|AAK01149.1| 878|Homo sapiens protein kinase D2 protein. 89 4e-17
M60725-1|AAA36411.1| 502|Homo sapiens p70 ribosomal S6 kinase a... 89 7e-17
M60724-1|AAA36410.1| 525|Homo sapiens p70 ribosomal S6 kinase a... 89 7e-17
BC117183-1|AAI17184.1| 926|Homo sapiens SNF1-like kinase 2 prot... 89 7e-17
BC113459-1|AAI13460.1| 926|Homo sapiens SNF1-like kinase 2 prot... 89 7e-17
BC053365-1|AAH53365.1| 451|Homo sapiens RPS6KB1 protein protein. 89 7e-17
BC035058-1|AAH35058.1| 351|Homo sapiens protein kinase, cAMP-de... 89 7e-17
AB084424-1|BAB91442.1| 346|Homo sapiens KIAA0781 protein protein. 89 7e-17
AB018324-1|BAA34501.3| 950|Homo sapiens KIAA0781 protein protein. 89 7e-17
X75346-1|CAA53094.1| 396|Homo sapiens MAP kinase activated prot... 88 9e-17
BC047896-1|AAH47896.1| 524|Homo sapiens RPS6KA4 protein protein. 88 9e-17
BC028079-1|AAH28079.1| 556|Homo sapiens Unknown (protein for IM... 88 9e-17
AC007390-1|AAY14817.1| 890|Homo sapiens unknown protein. 88 9e-17
AB015982-1|BAA36514.1| 890|Homo sapiens serine/threonine kinase... 88 9e-17
BC017575-1|AAH17575.1| 476|Homo sapiens CHK1 checkpoint homolog... 88 1e-16
BC004202-1|AAH04202.1| 476|Homo sapiens CHEK1 protein protein. 88 1e-16
AF527555-1|AAM78553.1| 476|Homo sapiens CHK1 checkpoint homolog... 88 1e-16
AF032874-1|AAB88852.1| 476|Homo sapiens protein kinase protein. 88 1e-16
AF016582-1|AAC51736.1| 476|Homo sapiens Chk1 protein. 88 1e-16
AB032387-1|BAA84577.1| 476|Homo sapiens checkpoint kinase protein. 88 1e-16
BC117311-1|AAI17312.1| 898|Homo sapiens CASK protein protein. 87 2e-16
AY705392-1|AAU10527.1| 921|Homo sapiens calcium/calmodulin-depe... 87 2e-16
AL627402-6|CAH71241.1| 590|Homo sapiens calcium/calmodulin-depe... 87 2e-16
AL627402-5|CAH71238.1| 897|Homo sapiens calcium/calmodulin-depe... 87 2e-16
AL627402-4|CAH71237.1| 909|Homo sapiens calcium/calmodulin-depe... 87 2e-16
AL627402-3|CAH71240.1| 926|Homo sapiens calcium/calmodulin-depe... 87 2e-16
AL627402-2|CAH71239.1| 921|Homo sapiens calcium/calmodulin-depe... 87 2e-16
AL603754-6|CAI41638.1| 590|Homo sapiens calcium/calmodulin-depe... 87 2e-16
AL603754-5|CAI41635.1| 926|Homo sapiens calcium/calmodulin-depe... 87 2e-16
AL603754-4|CAI41636.1| 921|Homo sapiens calcium/calmodulin-depe... 87 2e-16
AL603754-3|CAI41637.1| 897|Homo sapiens calcium/calmodulin-depe... 87 2e-16
AL603754-2|CAI41634.1| 909|Homo sapiens calcium/calmodulin-depe... 87 2e-16
AL445239-7|CAI41096.1| 590|Homo sapiens calcium/calmodulin-depe... 87 2e-16
AL445239-6|CAI41093.1| 926|Homo sapiens calcium/calmodulin-depe... 87 2e-16
AL445239-5|CAI41094.1| 921|Homo sapiens calcium/calmodulin-depe... 87 2e-16
AL445239-4|CAI41095.1| 897|Homo sapiens calcium/calmodulin-depe... 87 2e-16
AL445239-3|CAI41092.1| 909|Homo sapiens calcium/calmodulin-depe... 87 2e-16
AL353691-7|CAI42248.1| 590|Homo sapiens calcium/calmodulin-depe... 87 2e-16
AL353691-6|CAI42245.1| 926|Homo sapiens calcium/calmodulin-depe... 87 2e-16
AL353691-5|CAI42246.1| 921|Homo sapiens calcium/calmodulin-depe... 87 2e-16
AL353691-4|CAI42247.1| 897|Homo sapiens calcium/calmodulin-depe... 87 2e-16
AL353691-3|CAI42244.1| 909|Homo sapiens calcium/calmodulin-depe... 87 2e-16
AL158144-5|CAI42766.1| 590|Homo sapiens calcium/calmodulin-depe... 87 2e-16
AL158144-4|CAI42763.1| 926|Homo sapiens calcium/calmodulin-depe... 87 2e-16
AL158144-3|CAI42764.1| 921|Homo sapiens calcium/calmodulin-depe... 87 2e-16
AL158144-2|CAI42765.1| 897|Homo sapiens calcium/calmodulin-depe... 87 2e-16
AL158144-1|CAI42762.1| 909|Homo sapiens calcium/calmodulin-depe... 87 2e-16
AF035582-1|AAB88198.1| 897|Homo sapiens CASK protein. 87 2e-16
AF032119-1|AAB88125.1| 921|Homo sapiens hCASK protein. 87 2e-16
AB208859-1|BAD92096.1| 917|Homo sapiens calcium/calmodulin-depe... 87 2e-16
BC027464-1|AAH27464.1| 403|Homo sapiens aurora kinase A protein. 87 2e-16
BC006423-1|AAH06423.1| 403|Homo sapiens aurora kinase A protein. 87 2e-16
BC002499-1|AAH02499.1| 403|Homo sapiens AURKA protein protein. 87 2e-16
BC001280-1|AAH01280.1| 403|Homo sapiens aurora kinase A protein. 87 2e-16
AL121914-3|CAC12717.1| 403|Homo sapiens aurora kinase A protein. 87 2e-16
AF195947-1|AAF29508.1| 403|Homo sapiens STK15 serine/threonine ... 87 2e-16
AF011468-1|AAC63902.1| 403|Homo sapiens serine/threonine kinase... 87 2e-16
AF008551-1|AAC12708.1| 403|Homo sapiens aurora-related kinase 1... 87 2e-16
X80590-1|CAA56681.1| 387|Homo sapiens phosphorylase kinase prot... 87 3e-16
X07767-1|CAA30597.1| 351|Homo sapiens protein ( Human mRNA for ... 87 3e-16
DQ667173-1|ABG25918.1| 351|Homo sapiens protein kinase, cAMP-de... 87 3e-16
BC108259-1|AAI08260.1| 351|Homo sapiens protein kinase, cAMP-de... 87 3e-16
BC074753-1|AAH74753.1| 387|Homo sapiens phosphorylase kinase, g... 87 3e-16
BC069754-1|AAH69754.1| 387|Homo sapiens phosphorylase kinase, g... 87 3e-16
BC069738-1|AAH69738.1| 387|Homo sapiens phosphorylase kinase, g... 87 3e-16
BC069679-1|AAH69679.1| 387|Homo sapiens phosphorylase kinase, g... 87 3e-16
BC051327-1|AAH51327.1| 387|Homo sapiens phosphorylase kinase, g... 87 3e-16
BC039846-1|AAH39846.1| 351|Homo sapiens protein kinase, cAMP-de... 87 3e-16
AL390029-2|CAI15721.1| 740|Homo sapiens doublecortin and CaM ki... 87 3e-16
AL390029-1|CAI15720.1| 729|Homo sapiens doublecortin and CaM ki... 87 3e-16
AL160392-2|CAH70261.1| 740|Homo sapiens doublecortin and CaM ki... 87 3e-16
AL160392-1|CAH70262.1| 729|Homo sapiens doublecortin and CaM ki... 87 3e-16
AL157760-4|CAH70170.1| 433|Homo sapiens doublecortin and CaM ki... 87 3e-16
AL157760-2|CAH70168.1| 729|Homo sapiens doublecortin and CaM ki... 87 3e-16
AL157760-1|CAH70167.1| 740|Homo sapiens doublecortin and CaM ki... 87 3e-16
AL157694-2|CAH70657.1| 729|Homo sapiens doublecortin and CaM ki... 87 3e-16
AL157694-1|CAH70656.1| 740|Homo sapiens doublecortin and CaM ki... 87 3e-16
AF254253-1|AAL36972.1| 387|Homo sapiens phosphorylase kinase ga... 87 3e-16
AC092101-3|AAS07453.1| 387|Homo sapiens unknown protein. 87 3e-16
AB002367-1|BAA20824.2| 794|Homo sapiens KIAA0369 protein. 87 3e-16
AY505124-1|AAS86442.1| 778|Homo sapiens protein kinase SAD-B pr... 86 4e-16
AY458602-1|AAS10354.1| 778|Homo sapiens SAD1 kinase protein. 86 4e-16
AL807772-1|CAI39684.1| 227|Homo sapiens ribosomal protein S6 ki... 86 4e-16
AF479827-1|AAL87698.1| 778|Homo sapiens protein kinase-like pro... 86 4e-16
AF479826-1|AAL87697.1| 794|Homo sapiens putative serine/threoni... 86 4e-16
AY874862-1|AAX59898.1| 424|Homo sapiens SH3-binding kinase prot... 86 5e-16
AF125532-1|AAF17226.1| 414|Homo sapiens map kinase-interacting ... 86 5e-16
L33881-1|AAB17011.1| 587|Homo sapiens protein kinase C iota pro... 85 6e-16
L18964-1|AAA60171.1| 587|Homo sapiens protein kinase C iota pro... 85 6e-16
L14283-1|AAA36488.1| 592|Homo sapiens protein kinase C zeta pro... 85 6e-16
BC022016-1|AAH22016.3| 587|Homo sapiens protein kinase C, iota ... 85 6e-16
BC017187-1|AAH17187.1| 549|Homo sapiens ribosomal protein S6 ki... 85 6e-16
M34182-1|AAC41690.1| 360|Homo sapiens protein kinase A gamma-su... 85 8e-16
DQ667175-1|ABG25920.1| 351|Homo sapiens protein kinase, cAMP-de... 85 8e-16
BC039888-1|AAH39888.1| 351|Homo sapiens protein kinase, cAMP-de... 85 8e-16
AL162730-1|CAH71828.1| 351|Homo sapiens protein kinase, cAMP-de... 85 8e-16
AJ001597-1|CAA04863.1| 351|Homo sapiens cAMP-dependent protein ... 85 8e-16
Z15108-1|CAA78813.1| 584|Homo sapiens protein kinase C zeta pro... 85 1e-15
BT007082-1|AAP35745.1| 592|Homo sapiens protein kinase C, zeta ... 85 1e-15
BC073140-1|AAH73140.1| 414|Homo sapiens MAP kinase interacting ... 85 1e-15
BC039825-1|AAH39825.1| 457|Homo sapiens MAK protein protein. 85 1e-15
BC038504-1|AAH38504.1| 783|Homo sapiens SNF1-like kinase protein. 85 1e-15
BC014270-1|AAH14270.1| 592|Homo sapiens protein kinase C, zeta ... 85 1e-15
BC008058-1|AAH08058.1| 592|Homo sapiens protein kinase C, zeta ... 85 1e-15
AL645703-1|CAI21535.1| 592|Homo sapiens protein kinase C, zeta ... 85 1e-15
AL590822-6|CAI12484.1| 592|Homo sapiens protein kinase C, zeta ... 85 1e-15
AL391845-5|CAI15438.1| 592|Homo sapiens protein kinase C, zeta ... 85 1e-15
AL024498-4|CAB75823.1| 623|Homo sapiens protein ( Human DNA seq... 85 1e-15
AK131076-1|BAC85126.1| 764|Homo sapiens FLJ00263 protein protein. 85 1e-15
AF505623-1|AAN16405.1| 623|Homo sapiens male germ cell-associat... 85 1e-15
AF237776-1|AAG26337.1| 414|Homo sapiens MAP kinase-interacting ... 85 1e-15
AF237775-1|AAG26336.1| 465|Homo sapiens MAP kinase-interacting ... 85 1e-15
AC007136-1|AAD21217.1| 472|Homo sapiens Putative map kinase int... 85 1e-15
AB047786-1|BAD74070.1| 783|Homo sapiens serine/threonine protei... 85 1e-15
X75756-1|CAA53384.1| 912|Homo sapiens protein kinase C mu protein. 84 1e-15
U24153-1|AAA65442.1| 525|Homo sapiens p21-activated protein kin... 84 1e-15
DQ485452-1|ABE96833.1| 914|Homo sapiens protein kinase D1 protein. 84 1e-15
AF262405-1|AAF72667.1| 871|Homo sapiens calcium/calmodulin-depe... 84 1e-15
AF059681-1|AAC77369.1| 275|Homo sapiens serine/threonine kinase... 84 1e-15
BC036422-1|AAH36422.1| 436|Homo sapiens hypothetical protein MG... 83 3e-15
AB058714-1|BAB47440.1| 715|Homo sapiens KIAA1811 protein protein. 83 3e-15
D84212-1|BAA23592.1| 402|Homo sapiens aurora/IPL1-related kinas... 82 6e-15
BC125199-1|AAI25200.1| 936|Homo sapiens PKN2 protein protein. 82 6e-15
BC069655-1|AAH69655.1| 390|Homo sapiens PHKG1 protein protein. 82 6e-15
U33052-1|AAC50208.1| 984|Homo sapiens PRK2 protein. 82 8e-15
S75548-1|AAB33346.1| 984|Homo sapiens protein kinase PRK2 protein. 82 8e-15
BC075064-1|AAH75064.2| 275|Homo sapiens AURKC protein protein. 82 8e-15
BC062558-1|AAH62558.1| 889|Homo sapiens protein kinase N3 protein. 82 8e-15
BC035807-1|AAH35807.1| 292|Homo sapiens ICK protein protein. 82 8e-15
BC031231-1|AAH31231.1| 514|Homo sapiens serine/threonine kinase... 82 8e-15
AY714054-1|AAU04399.1| 306|Homo sapiens aurora-C protein. 82 8e-15
AY661554-1|AAT64422.1| 290|Homo sapiens aurora/Ipl1-related kin... 82 8e-15
AL441992-1|CAI15401.1| 889|Homo sapiens protein kinase N3 protein. 82 8e-15
AL162581-2|CAI19518.1| 632|Homo sapiens RP1-132F22.1 protein. 82 8e-15
AL136381-3|CAI23271.1| 984|Homo sapiens protein kinase N2 protein. 82 8e-15
AL031178-1|CAI20261.1| 632|Homo sapiens RP1-132F22.1 protein. 82 8e-15
AK093251-1|BAC04109.1| 514|Homo sapiens protein ( Homo sapiens ... 82 8e-15
AJ303380-1|CAC29064.1| 514|Homo sapiens serine/threonine kinase... 82 8e-15
AF152469-1|AAG43364.1| 632|Homo sapiens MAK-related kinase prot... 82 8e-15
AB023153-1|BAA76780.2| 640|Homo sapiens KIAA0936 protein protein. 82 8e-15
AB017332-1|BAA76292.1| 309|Homo sapiens Aurora/Ipl1-related kin... 82 8e-15
Z84486-1|CAI21678.1| 526|Homo sapiens serum/glucocorticoid regu... 81 1e-14
Y10032-1|CAA71138.1| 431|Homo sapiens serine/threonine protein ... 81 1e-14
M63167-1|AAA36539.1| 480|Homo sapiens rac protein kinase-alpha ... 81 1e-14
D87931-1|BAA75636.1| 1388|Homo sapiens Rho kinase protein. 81 1e-14
BC084538-1|AAH84538.1| 480|Homo sapiens v-akt murine thymoma vi... 81 1e-14
BC001263-1|AAH01263.1| 431|Homo sapiens serum/glucocorticoid re... 81 1e-14
BC000479-1|AAH00479.1| 480|Homo sapiens v-akt murine thymoma vi... 81 1e-14
AL355881-2|CAH72579.1| 526|Homo sapiens serum/glucocorticoid re... 81 1e-14
AL135839-4|CAI19721.1| 526|Homo sapiens serum/glucocorticoid re... 81 1e-14
AL135839-3|CAI19720.1| 445|Homo sapiens serum/glucocorticoid re... 81 1e-14
AL135839-2|CAI19719.1| 431|Homo sapiens serum/glucocorticoid re... 81 1e-14
AL135839-1|CAI19718.1| 421|Homo sapiens serum/glucocorticoid re... 81 1e-14
AJ000512-1|CAA04146.1| 431|Homo sapiens serine/threonine protei... 81 1e-14
AF283830-1|AAL55732.1| 480|Homo sapiens AKT1 protein. 81 1e-14
AF153609-1|AAD41091.1| 431|Homo sapiens serine/threonine protei... 81 1e-14
AF054621-1|AAC25955.1| 309|Homo sapiens serine/threonine kinase... 81 1e-14
X80229-1|CAA56515.1| 479|Homo sapiens serine/threonine protein ... 81 1e-14
AB019692-1|BAA85625.1| 889|Homo sapiens protein kinase PKNbeta ... 81 1e-14
BC037268-1|AAH37268.1| 683|Homo sapiens protein kinase C, eta p... 81 2e-14
AL450063-10|CAI16853.1| 209|Homo sapiens protein kinase, cAMP-d... 81 2e-14
AL450063-9|CAI16852.1| 197|Homo sapiens protein kinase, cAMP-de... 81 2e-14
AL450063-8|CAI16851.1| 206|Homo sapiens protein kinase, cAMP-de... 81 2e-14
AL450063-6|CAI16849.1| 214|Homo sapiens protein kinase, cAMP-de... 81 2e-14
U33053-1|AAC50209.1| 942|Homo sapiens PRK1 protein. 80 2e-14
S75546-1|AAB33345.1| 942|Homo sapiens protein kinase PRK1 protein. 80 2e-14
M55284-1|AAA60100.1| 682|Homo sapiens protein kinase C-L protein. 80 2e-14
D26181-1|BAA05169.1| 942|Homo sapiens PKN protein. 80 2e-14
BC040061-1|AAH40061.1| 942|Homo sapiens protein kinase N1 protein. 80 2e-14
AC093645-1|AAP22356.1| 161|Homo sapiens unknown protein. 80 2e-14
AC018463-2|AAX93049.1| 1337|Homo sapiens unknown protein. 80 2e-14
AB014519-1|BAA31594.2| 1428|Homo sapiens KIAA0619 protein protein. 80 2e-14
X85545-1|CAA59733.1| 358|Homo sapiens protein kinase protein. 80 3e-14
BC114491-1|AAI14492.1| 1189|Homo sapiens NEK1 protein protein. 80 3e-14
BC041073-1|AAH41073.1| 358|Homo sapiens protein kinase, X-linke... 80 3e-14
BC015147-1|AAH15147.1| 403|Homo sapiens Unknown (protein for IM... 80 3e-14
AB067488-1|BAB67794.1| 1265|Homo sapiens KIAA1901 protein protein. 80 3e-14
AB011446-1|BAA82709.1| 343|Homo sapiens Aik2 protein. 80 3e-14
BC065499-1|AAH65499.1| 1797|Homo sapiens microtubule associated ... 79 4e-14
BC015816-1|AAH15816.2| 792|Homo sapiens MAST2 protein protein. 79 4e-14
BC012622-1|AAH12622.1| 207|Homo sapiens PRKAA1 protein protein. 79 4e-14
BC006166-1|AAH06166.1| 792|Homo sapiens MAST2 protein protein. 79 4e-14
AL645480-2|CAH73245.1| 792|Homo sapiens microtubule associated ... 79 4e-14
AL645480-1|CAH73244.1| 1798|Homo sapiens microtubule associated ... 79 4e-14
AL603888-3|CAI16563.1| 792|Homo sapiens microtubule associated ... 79 4e-14
AL603888-2|CAI16562.1| 1798|Homo sapiens microtubule associated ... 79 4e-14
AL603882-2|CAI16217.1| 1798|Homo sapiens microtubule associated ... 79 4e-14
AL357774-2|CAI40843.1| 544|Homo sapiens p21 (CDKN1A)-activated ... 79 4e-14
AL357774-1|CAI40844.1| 559|Homo sapiens p21 (CDKN1A)-activated ... 79 4e-14
AL117326-3|CAI43168.1| 559|Homo sapiens p21 (CDKN1A)-activated ... 79 4e-14
AL117326-2|CAI43167.1| 544|Homo sapiens p21 (CDKN1A)-activated ... 79 4e-14
AL031117-6|CAI43157.1| 544|Homo sapiens p21 (CDKN1A)-activated ... 79 4e-14
AL031117-5|CAI43158.1| 559|Homo sapiens p21 (CDKN1A)-activated ... 79 4e-14
AF225919-1|AAF37278.1| 632|Homo sapiens intestinal cell kinase ... 79 4e-14
AF155651-1|AAF67008.1| 544|Homo sapiens P21-activated kinase 3 ... 79 4e-14
AF068864-1|AAC36097.1| 544|Homo sapiens p21-activated kinase 3 ... 79 4e-14
AB102659-1|BAC81128.1| 559|Homo sapiens p21-activated kinase 3 ... 79 4e-14
Z98752-8|CAI42315.1| 366|Homo sapiens serum/glucocorticoid regu... 79 5e-14
U22456-1|AAA64850.1| 174|Homo sapiens AMP-activated protein kin... 79 5e-14
BT019534-1|AAV38341.1| 344|Homo sapiens serine/threonine kinase... 79 5e-14
BC080581-1|AAH80581.1| 344|Homo sapiens aurora kinase B protein. 79 5e-14
BC024179-1|AAH24179.1| 719|Homo sapiens p21(CDKN1A)-activated k... 79 5e-14
BC000442-1|AAH00442.3| 344|Homo sapiens aurora kinase B protein. 79 5e-14
AL353612-1|CAI23529.1| 719|Homo sapiens p21(CDKN1A)-activated k... 79 5e-14
AL135935-1|CAH71126.1| 719|Homo sapiens p21(CDKN1A)-activated k... 79 5e-14
AL031652-1|CAI42211.1| 719|Homo sapiens p21(CDKN1A)-activated k... 79 5e-14
AF008552-1|AAC12709.1| 344|Homo sapiens aurora-related kinase 2... 79 5e-14
AB040812-1|BAA94194.1| 719|Homo sapiens protein kinase PAK5 pro... 79 5e-14
AB033090-1|BAA86578.1| 753|Homo sapiens KIAA1264 protein protein. 79 5e-14
AB011450-1|BAA32136.1| 344|Homo sapiens aurora and IPL1-like mi... 79 5e-14
BC056423-1|AAH56423.1| 214|Homo sapiens ULK3 protein protein. 79 7e-14
BC036117-1|AAH36117.1| 214|Homo sapiens ULK3 protein protein. 79 7e-14
BC013300-1|AAH13300.2| 371|Homo sapiens AURKB protein protein. 79 7e-14
BC009751-1|AAH09751.1| 344|Homo sapiens aurora kinase B protein. 79 7e-14
AY033608-1|AAK52330.1| 335|Homo sapiens extracellular signal-re... 79 7e-14
AP001751-1|BAA95536.1| 786|Homo sapiens SNF1LK protein. 79 7e-14
X61037-1|CAA43372.1| 417|Homo sapiens human protein kinase B p... 78 9e-14
X52479-1|CAA36718.1| 672|Homo sapiens protein ( Human PKC alpha... 78 9e-14
BC128510-1|AAI28511.1| 1203|Homo sapiens KIAA0999 protein protein. 78 9e-14
BC109274-1|AAI09275.1| 672|Homo sapiens protein kinase C, alpha... 78 9e-14
BC109273-1|AAI09274.1| 672|Homo sapiens protein kinase C, alpha... 78 9e-14
AY633609-1|AAV33302.1| 672|Homo sapiens aging-associated gene 6... 78 9e-14
AB023216-1|BAA76843.2| 1371|Homo sapiens KIAA0999 protein protein. 78 9e-14
BC064422-1|AAH64422.1| 241|Homo sapiens PNCK protein protein. 78 1e-13
AL136373-3|CAI14763.1| 266|Homo sapiens MAP kinase interacting ... 78 1e-13
AJ252239-1|CAB65123.1| 243|Homo sapiens calcium/calmodulin depe... 78 1e-13
U25975-1|AAA75468.1| 493|Homo sapiens hPAK65 protein. 77 2e-13
BT020098-1|AAV38901.1| 367|Homo sapiens serum/glucocorticoid re... 77 2e-13
BC069613-1|AAH69613.1| 524|Homo sapiens p21-activated kinase 2 ... 77 2e-13
BC053536-1|AAH53536.1| 231|Homo sapiens RAGE protein protein. 77 2e-13
AB022694-1|BAA81688.1| 419|Homo sapiens MOK protein kinase prot... 77 2e-13
>BC132833-1|AAI32834.1| 388|Homo sapiens hypothetical protein
LOC340156 protein.
Length = 388
Score = 137 bits (332), Expect = 1e-31
Identities = 79/269 (29%), Positives = 143/269 (53%), Gaps = 10/269 (3%)
Query: 230 KLIGSGVYGKVMLIRSNA-GKQFVAKTVISQYQTNSMEEYSTLRILRNTP--NIVKLIEC 286
+++G G +G+V A G + AK + ++ + E + + ++ N+++L +
Sbjct: 110 EILGGGRFGQVHKCEETATGLKLAAKIIKTRGMKDKEEVKNEISVMNQLDHANLIQLYDA 169
Query: 287 YSDGLNWVFVMENLWGGNLFDRFKHHQC-ISERDIKIYLRQVCSGLQYIHNNGLIHFDIK 345
+ + V VME + GG LFDR ++E D ++++Q+C G++++H ++H D+K
Sbjct: 170 FESKNDIVLVMEYVDGGELFDRIIDESYNLTELDTILFMKQICEGIRHMHQMYILHLDLK 229
Query: 346 PENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLTTAYDMWSV 405
PEN++C + + IKIIDFGL + + R + NFG +APE+ + + ++ DMWSV
Sbjct: 230 PENILCVNRDAKQIKIIDFGLARRYKPREKLKVNFGTPEFLAPEVVNYDFVSFPTDMWSV 289
Query: 406 GILMGIGLLGYTPRIIGKRSRRLSVVFT------SQEYLCISGAALHFFGKCLHTNPSRR 459
G++ + L G +P + + L+ + +E+ IS A F K L S R
Sbjct: 290 GVIAYMLLSGLSPFLGDNDAETLNNILACRWDLEDEEFQDISEEAKEFISKLLIKEKSWR 349
Query: 460 LTAAQALNHPWMFDTCPHPLSWKKPSKNR 488
++A++AL HPW+ D H + KNR
Sbjct: 350 ISASEALKHPWLSDHKLHSRLNAQKKKNR 378
>BC132831-1|AAI32832.1| 388|Homo sapiens hypothetical protein
LOC340156 protein.
Length = 388
Score = 137 bits (332), Expect = 1e-31
Identities = 79/269 (29%), Positives = 143/269 (53%), Gaps = 10/269 (3%)
Query: 230 KLIGSGVYGKVMLIRSNA-GKQFVAKTVISQYQTNSMEEYSTLRILRNTP--NIVKLIEC 286
+++G G +G+V A G + AK + ++ + E + + ++ N+++L +
Sbjct: 110 EILGGGRFGQVHKCEETATGLKLAAKIIKTRGMKDKEEVKNEISVMNQLDHANLIQLYDA 169
Query: 287 YSDGLNWVFVMENLWGGNLFDRFKHHQC-ISERDIKIYLRQVCSGLQYIHNNGLIHFDIK 345
+ + V VME + GG LFDR ++E D ++++Q+C G++++H ++H D+K
Sbjct: 170 FESKNDIVLVMEYVDGGELFDRIIDESYNLTELDTILFMKQICEGIRHMHQMYILHLDLK 229
Query: 346 PENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLTTAYDMWSV 405
PEN++C + + IKIIDFGL + + R + NFG +APE+ + + ++ DMWSV
Sbjct: 230 PENILCVNRDAKQIKIIDFGLARRYKPREKLKVNFGTPEFLAPEVVNYDFVSFPTDMWSV 289
Query: 406 GILMGIGLLGYTPRIIGKRSRRLSVVFT------SQEYLCISGAALHFFGKCLHTNPSRR 459
G++ + L G +P + + L+ + +E+ IS A F K L S R
Sbjct: 290 GVIAYMLLSGLSPFLGDNDAETLNNILACRWDLEDEEFQDISEEAKEFISKLLIKEKSWR 349
Query: 460 LTAAQALNHPWMFDTCPHPLSWKKPSKNR 488
++A++AL HPW+ D H + KNR
Sbjct: 350 ISASEALKHPWLSDHKLHSRLNAQKKKNR 378
>AL139092-1|CAH73662.1| 388|Homo sapiens protein ( Human DNA
sequence from clone RP11-420G6 on chromosome 6. ).
Length = 388
Score = 137 bits (332), Expect = 1e-31
Identities = 79/269 (29%), Positives = 143/269 (53%), Gaps = 10/269 (3%)
Query: 230 KLIGSGVYGKVMLIRSNA-GKQFVAKTVISQYQTNSMEEYSTLRILRNTP--NIVKLIEC 286
+++G G +G+V A G + AK + ++ + E + + ++ N+++L +
Sbjct: 110 EILGGGRFGQVHKCEETATGLKLAAKIIKTRGMKDKEEVKNEISVMNQLDHANLIQLYDA 169
Query: 287 YSDGLNWVFVMENLWGGNLFDRFKHHQC-ISERDIKIYLRQVCSGLQYIHNNGLIHFDIK 345
+ + V VME + GG LFDR ++E D ++++Q+C G++++H ++H D+K
Sbjct: 170 FESKNDIVLVMEYVDGGELFDRIIDESYNLTELDTILFMKQICEGIRHMHQMYILHLDLK 229
Query: 346 PENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLTTAYDMWSV 405
PEN++C + + IKIIDFGL + + R + NFG +APE+ + + ++ DMWSV
Sbjct: 230 PENILCVNRDAKQIKIIDFGLARRYKPREKLKVNFGTPEFLAPEVVNYDFVSFPTDMWSV 289
Query: 406 GILMGIGLLGYTPRIIGKRSRRLSVVFT------SQEYLCISGAALHFFGKCLHTNPSRR 459
G++ + L G +P + + L+ + +E+ IS A F K L S R
Sbjct: 290 GVIAYMLLSGLSPFLGDNDAETLNNILACRWDLEDEEFQDISEEAKEFISKLLIKEKSWR 349
Query: 460 LTAAQALNHPWMFDTCPHPLSWKKPSKNR 488
++A++AL HPW+ D H + KNR
Sbjct: 350 ISASEALKHPWLSDHKLHSRLNAQKKKNR 378
>AL138876-2|CAI12221.2| 388|Homo sapiens protein ( Human DNA
sequence from clone RP11-145H9 on chromosome 6. ).
Length = 388
Score = 137 bits (332), Expect = 1e-31
Identities = 79/269 (29%), Positives = 143/269 (53%), Gaps = 10/269 (3%)
Query: 230 KLIGSGVYGKVMLIRSNA-GKQFVAKTVISQYQTNSMEEYSTLRILRNTP--NIVKLIEC 286
+++G G +G+V A G + AK + ++ + E + + ++ N+++L +
Sbjct: 110 EILGGGRFGQVHKCEETATGLKLAAKIIKTRGMKDKEEVKNEISVMNQLDHANLIQLYDA 169
Query: 287 YSDGLNWVFVMENLWGGNLFDRFKHHQC-ISERDIKIYLRQVCSGLQYIHNNGLIHFDIK 345
+ + V VME + GG LFDR ++E D ++++Q+C G++++H ++H D+K
Sbjct: 170 FESKNDIVLVMEYVDGGELFDRIIDESYNLTELDTILFMKQICEGIRHMHQMYILHLDLK 229
Query: 346 PENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLTTAYDMWSV 405
PEN++C + + IKIIDFGL + + R + NFG +APE+ + + ++ DMWSV
Sbjct: 230 PENILCVNRDAKQIKIIDFGLARRYKPREKLKVNFGTPEFLAPEVVNYDFVSFPTDMWSV 289
Query: 406 GILMGIGLLGYTPRIIGKRSRRLSVVFT------SQEYLCISGAALHFFGKCLHTNPSRR 459
G++ + L G +P + + L+ + +E+ IS A F K L S R
Sbjct: 290 GVIAYMLLSGLSPFLGDNDAETLNNILACRWDLEDEEFQDISEEAKEFISKLLIKEKSWR 349
Query: 460 LTAAQALNHPWMFDTCPHPLSWKKPSKNR 488
++A++AL HPW+ D H + KNR
Sbjct: 350 ISASEALKHPWLSDHKLHSRLNAQKKKNR 378
>X90870-1|CAA62378.1| 458|Homo sapiens myosin-light-chain kinase
protein.
Length = 458
Score = 136 bits (330), Expect = 2e-31
Identities = 86/277 (31%), Positives = 142/277 (51%), Gaps = 14/277 (5%)
Query: 232 IGSGVYGKVM-LIRSNAGKQFVAK---TVISQYQTNSMEEYSTLRILRNTPNIVKLIECY 287
+GSG +G+V L+ K + K ++ + N +E S + L + P +V+ ++ +
Sbjct: 15 LGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIMNCLHH-PKLVQCVDAF 73
Query: 288 SDGLNWVFVMENLWGGNLFDRFKHHQC-ISERDIKIYLRQVCSGLQYIHNNGLIHFDIKP 346
+ N V V+E + GG LF+R ++ER+ Y+RQ+ G++YIH G++H D+KP
Sbjct: 74 EEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYIHKQGIVHLDLKP 133
Query: 347 ENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLTTAYDMWSVG 406
EN+MC + IK+IDFGL + + + FG VAPE+ + + A DMWS+G
Sbjct: 134 ENIMCVNKTGTRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVINYEPIGYATDMWSIG 193
Query: 407 ILMGIGLLGYTPRIIGKRSRRLSVV------FTSQEYLCISGAALHFFGKCLHTNPSRRL 460
++ I + G +P + + L+ V F + + IS A F L + RL
Sbjct: 194 VICYILVSGLSPFMGDNDNETLANVTSATWDFDDEAFDEISDDAKDFISNLLKKDMKNRL 253
Query: 461 TAAQALNHPWMFDTCPHPLSWKKPSKNRRYNRYMGQR 497
Q L HPW+ + + KK SK+ R +YM +R
Sbjct: 254 DCTQCLQHPWLMKDTKN-MEAKKLSKD-RMKKYMARR 288
>U48959-1|AAC18423.2| 1914|Homo sapiens myosin light chain kinase
protein.
Length = 1914
Score = 136 bits (330), Expect = 2e-31
Identities = 86/277 (31%), Positives = 142/277 (51%), Gaps = 14/277 (5%)
Query: 232 IGSGVYGKVM-LIRSNAGKQFVAK---TVISQYQTNSMEEYSTLRILRNTPNIVKLIECY 287
+GSG +G+V L+ K + K ++ + N +E S + L + P +V+ ++ +
Sbjct: 1470 LGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIMNCLHH-PKLVQCVDAF 1528
Query: 288 SDGLNWVFVMENLWGGNLFDRFKHHQC-ISERDIKIYLRQVCSGLQYIHNNGLIHFDIKP 346
+ N V V+E + GG LF+R ++ER+ Y+RQ+ G++YIH G++H D+KP
Sbjct: 1529 EEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYIHKQGIVHLDLKP 1588
Query: 347 ENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLTTAYDMWSVG 406
EN+MC + IK+IDFGL + + + FG VAPE+ + + A DMWS+G
Sbjct: 1589 ENIMCVNKTGTRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVINYEPIGYATDMWSIG 1648
Query: 407 ILMGIGLLGYTPRIIGKRSRRLSVV------FTSQEYLCISGAALHFFGKCLHTNPSRRL 460
++ I + G +P + + L+ V F + + IS A F L + RL
Sbjct: 1649 VICYILVSGLSPFMGDNDNETLANVTSATWDFDDEAFDEISDDAKDFISNLLKKDMKNRL 1708
Query: 461 TAAQALNHPWMFDTCPHPLSWKKPSKNRRYNRYMGQR 497
Q L HPW+ + + KK SK+ R +YM +R
Sbjct: 1709 DCTQCLQHPWLMKDTKN-MEAKKLSKD-RMKKYMARR 1743
>AY339601-1|AAQ02673.1| 1914|Homo sapiens long myosin light chain
kinase protein.
Length = 1914
Score = 136 bits (330), Expect = 2e-31
Identities = 86/277 (31%), Positives = 142/277 (51%), Gaps = 14/277 (5%)
Query: 232 IGSGVYGKVM-LIRSNAGKQFVAK---TVISQYQTNSMEEYSTLRILRNTPNIVKLIECY 287
+GSG +G+V L+ K + K ++ + N +E S + L + P +V+ ++ +
Sbjct: 1470 LGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIMNCLHH-PKLVQCVDAF 1528
Query: 288 SDGLNWVFVMENLWGGNLFDRFKHHQC-ISERDIKIYLRQVCSGLQYIHNNGLIHFDIKP 346
+ N V V+E + GG LF+R ++ER+ Y+RQ+ G++YIH G++H D+KP
Sbjct: 1529 EEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYIHKQGIVHLDLKP 1588
Query: 347 ENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLTTAYDMWSVG 406
EN+MC + IK+IDFGL + + + FG VAPE+ + + A DMWS+G
Sbjct: 1589 ENIMCVNKTGTRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVINYEPIGYATDMWSIG 1648
Query: 407 ILMGIGLLGYTPRIIGKRSRRLSVV------FTSQEYLCISGAALHFFGKCLHTNPSRRL 460
++ I + G +P + + L+ V F + + IS A F L + RL
Sbjct: 1649 VICYILVSGLSPFMGDNDNETLANVTSATWDFDDEAFDEISDDAKDFISNLLKKDMKNRL 1708
Query: 461 TAAQALNHPWMFDTCPHPLSWKKPSKNRRYNRYMGQR 497
Q L HPW+ + + KK SK+ R +YM +R
Sbjct: 1709 DCTQCLQHPWLMKDTKN-MEAKKLSKD-RMKKYMARR 1743
>AF069601-1|AAD15921.2| 1845|Homo sapiens myosin light chain kinase
isoform 2 protein.
Length = 1845
Score = 136 bits (330), Expect = 2e-31
Identities = 86/277 (31%), Positives = 142/277 (51%), Gaps = 14/277 (5%)
Query: 232 IGSGVYGKVM-LIRSNAGKQFVAK---TVISQYQTNSMEEYSTLRILRNTPNIVKLIECY 287
+GSG +G+V L+ K + K ++ + N +E S + L + P +V+ ++ +
Sbjct: 1401 LGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIMNCLHH-PKLVQCVDAF 1459
Query: 288 SDGLNWVFVMENLWGGNLFDRFKHHQC-ISERDIKIYLRQVCSGLQYIHNNGLIHFDIKP 346
+ N V V+E + GG LF+R ++ER+ Y+RQ+ G++YIH G++H D+KP
Sbjct: 1460 EEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYIHKQGIVHLDLKP 1519
Query: 347 ENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLTTAYDMWSVG 406
EN+MC + IK+IDFGL + + + FG VAPE+ + + A DMWS+G
Sbjct: 1520 ENIMCVNKTGTRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVINYEPIGYATDMWSIG 1579
Query: 407 ILMGIGLLGYTPRIIGKRSRRLSVV------FTSQEYLCISGAALHFFGKCLHTNPSRRL 460
++ I + G +P + + L+ V F + + IS A F L + RL
Sbjct: 1580 VICYILVSGLSPFMGDNDNETLANVTSATWDFDDEAFDEISDDAKDFISNLLKKDMKNRL 1639
Query: 461 TAAQALNHPWMFDTCPHPLSWKKPSKNRRYNRYMGQR 497
Q L HPW+ + + KK SK+ R +YM +R
Sbjct: 1640 DCTQCLQHPWLMKDTKN-MEAKKLSKD-RMKKYMARR 1674
>AB037663-1|BAB21504.1| 992|Homo sapiens myosin light chain kinase
protein.
Length = 992
Score = 136 bits (330), Expect = 2e-31
Identities = 86/277 (31%), Positives = 142/277 (51%), Gaps = 14/277 (5%)
Query: 232 IGSGVYGKVM-LIRSNAGKQFVAK---TVISQYQTNSMEEYSTLRILRNTPNIVKLIECY 287
+GSG +G+V L+ K + K ++ + N +E S + L + P +V+ ++ +
Sbjct: 548 LGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIMNCLHH-PKLVQCVDAF 606
Query: 288 SDGLNWVFVMENLWGGNLFDRFKHHQC-ISERDIKIYLRQVCSGLQYIHNNGLIHFDIKP 346
+ N V V+E + GG LF+R ++ER+ Y+RQ+ G++YIH G++H D+KP
Sbjct: 607 EEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYIHKQGIVHLDLKP 666
Query: 347 ENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLTTAYDMWSVG 406
EN+MC + IK+IDFGL + + + FG VAPE+ + + A DMWS+G
Sbjct: 667 ENIMCVNKTGTRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVINYEPIGYATDMWSIG 726
Query: 407 ILMGIGLLGYTPRIIGKRSRRLSVV------FTSQEYLCISGAALHFFGKCLHTNPSRRL 460
++ I + G +P + + L+ V F + + IS A F L + RL
Sbjct: 727 VICYILVSGLSPFMGDNDNETLANVTSATWDFDDEAFDEISDDAKDFISNLLKKDMKNRL 786
Query: 461 TAAQALNHPWMFDTCPHPLSWKKPSKNRRYNRYMGQR 497
Q L HPW+ + + KK SK+ R +YM +R
Sbjct: 787 DCTQCLQHPWLMKDTKN-MEAKKLSKD-RMKKYMARR 821
>AY424270-1|AAR29062.1| 1914|Homo sapiens myosin lignt chain
polypeptide kinase isoform 1 protein.
Length = 1914
Score = 135 bits (326), Expect = 6e-31
Identities = 86/277 (31%), Positives = 141/277 (50%), Gaps = 14/277 (5%)
Query: 232 IGSGVYGKVM-LIRSNAGKQFVAK---TVISQYQTNSMEEYSTLRILRNTPNIVKLIECY 287
+GSG +G+V L+ K + K ++ + N +E S + L + P +V+ ++ +
Sbjct: 1470 LGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIMNCL-HPPKLVQCVDAF 1528
Query: 288 SDGLNWVFVMENLWGGNLFDRFKHHQC-ISERDIKIYLRQVCSGLQYIHNNGLIHFDIKP 346
+ N V V+E + GG LF+R ++ER+ Y+RQ+ G++YIH G++H D+KP
Sbjct: 1529 EEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYIHKQGIVHLDLKP 1588
Query: 347 ENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLTTAYDMWSVG 406
EN+MC + IK+IDFGL + + + FG VAPE+ + A DMWS+G
Sbjct: 1589 ENIMCVNKTGTRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVIIYEPIGYATDMWSIG 1648
Query: 407 ILMGIGLLGYTPRIIGKRSRRLSVV------FTSQEYLCISGAALHFFGKCLHTNPSRRL 460
++ I + G +P + + L+ V F + + IS A F L + RL
Sbjct: 1649 VICYILVSGLSPFMGDNDNETLANVTSPTWDFDDEAFDEISDDAKDFISNLLKKDMKNRL 1708
Query: 461 TAAQALNHPWMFDTCPHPLSWKKPSKNRRYNRYMGQR 497
Q L HPW+ + + KK SK+ R +YM +R
Sbjct: 1709 DCTQCLQHPWLMKDTKN-MEAKKLSKD-RMKKYMARR 1743
>AY424269-1|AAR29061.1| 1845|Homo sapiens myosin light chain
polypeptide kinase isoform 2 protein.
Length = 1845
Score = 135 bits (326), Expect = 6e-31
Identities = 86/277 (31%), Positives = 141/277 (50%), Gaps = 14/277 (5%)
Query: 232 IGSGVYGKVM-LIRSNAGKQFVAK---TVISQYQTNSMEEYSTLRILRNTPNIVKLIECY 287
+GSG +G+V L+ K + K ++ + N +E S + L + P +V+ ++ +
Sbjct: 1401 LGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIMNCL-HPPKLVQCVDAF 1459
Query: 288 SDGLNWVFVMENLWGGNLFDRFKHHQC-ISERDIKIYLRQVCSGLQYIHNNGLIHFDIKP 346
+ N V V+E + GG LF+R ++ER+ Y+RQ+ G++YIH G++H D+KP
Sbjct: 1460 EEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYIHKQGIVHLDLKP 1519
Query: 347 ENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLTTAYDMWSVG 406
EN+MC + IK+IDFGL + + + FG VAPE+ + A DMWS+G
Sbjct: 1520 ENIMCVNKTGTRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVIIYEPIGYATDMWSIG 1579
Query: 407 ILMGIGLLGYTPRIIGKRSRRLSVV------FTSQEYLCISGAALHFFGKCLHTNPSRRL 460
++ I + G +P + + L+ V F + + IS A F L + RL
Sbjct: 1580 VICYILVSGLSPFMGDNDNETLANVTSPTWDFDDEAFDEISDDAKDFISNLLKKDMKNRL 1639
Query: 461 TAAQALNHPWMFDTCPHPLSWKKPSKNRRYNRYMGQR 497
Q L HPW+ + + KK SK+ R +YM +R
Sbjct: 1640 DCTQCLQHPWLMKDTKN-MEAKKLSKD-RMKKYMARR 1674
>X85337-1|CAA59685.1| 991|Homo sapiens myosin light chain kinase
protein.
Length = 991
Score = 131 bits (317), Expect = 7e-30
Identities = 85/277 (30%), Positives = 140/277 (50%), Gaps = 14/277 (5%)
Query: 232 IGSGVYGKVM-LIRSNAGKQFVAK---TVISQYQTNSMEEYSTLRILRNTPNIVKLIECY 287
+GSG +G+ L+ K + K ++ + N +E S + L + P +V+ ++ +
Sbjct: 548 LGSGKFGQCFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIMNCLHH-PKLVQCVDAF 606
Query: 288 SDGLNWVFVMENLWGGNLFDRFKHHQC-ISERDIKIYLRQVCSGLQYIHNNGLIHFDIKP 346
+ N V V+E + GG LF+R ++ER+ Y+RQ+ G++YIH G++H D+KP
Sbjct: 607 EEKANIVMVLEIVSGGELFERIIDEDFELTERECTKYMRQISEGVEYIHKQGIVHLDLKP 666
Query: 347 ENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLTTAYDMWSVG 406
EN+MC + IK+IDFGL + + + FG VAPE+ + + A DMWS+
Sbjct: 667 ENIMCVNKTGTRIKLIDFGLPRRLENAGSLKVLFGTPEFVAPEVINYEPIRYATDMWSIR 726
Query: 407 ILMGIGLLGYTPRIIGKRSRRLSVV------FTSQEYLCISGAALHFFGKCLHTNPSRRL 460
++ I + G P + + L+ V F + + IS A F L + RL
Sbjct: 727 VICYILVSGPFPFMGDNDNETLANVTSATWDFDDEAFDEISDDAKDFISNLLKKDMKNRL 786
Query: 461 TAAQALNHPWMFDTCPHPLSWKKPSKNRRYNRYMGQR 497
AQ L HPW+ + + KK SK+ R +YM +R
Sbjct: 787 DLAQCLQHPWLMKDTKN-MEAKKLSKD-RMKKYMARR 821
>BC047696-1|AAH47696.1| 414|Homo sapiens serine/threonine kinase
17a protein.
Length = 414
Score = 130 bits (314), Expect = 2e-29
Identities = 74/259 (28%), Positives = 139/259 (53%), Gaps = 15/259 (5%)
Query: 228 PLKLIGSGVYGKVM-LIRSNAGKQFVAKTVISQY--QTNSME---EYSTLRILRNTPNIV 281
P + +G G + V I+ ++GK+F AK + + Q ME E + L + ++ P ++
Sbjct: 63 PGRELGRGKFAVVRKCIKKDSGKEFAAKFMRKRRKGQDCRMEIIHEIAVLELAQDNPWVI 122
Query: 282 KLIECYSDGLNWVFVMENLWGGNLFDRF--KHHQCISERDIKIYLRQVCSGLQYIHNNGL 339
L E Y + V+E GG +FD+ + E+D++ +RQ+ G+ ++H +
Sbjct: 123 NLHEVYETASEMILVLEYAAGGEIFDQCVADREEAFKEKDVQRLMRQILEGVHFLHTRDV 182
Query: 340 IHFDIKPENVMCCSLNCL-NIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLTT 398
+H D+KP+N++ S + L +IKI+DFGL++ ++ + G VAPE+ S + ++
Sbjct: 183 VHLDLKPQNILLTSESPLGDIKIVDFGLSRILKNSEELREIMGTPEYVAPEILSYDPISM 242
Query: 399 AYDMWSVGILMGIGLLGYTPRIIGKRSR------RLSVVFTSQEYLCISGAALHFFGKCL 452
A DMWS+G+L + L G +P + + ++++ ++ +E+ +S +A+ F L
Sbjct: 243 ATDMWSIGVLTYVMLTGISPFLGNDKQETFLNISQMNLSYSEEEFDVLSESAVDFIRTLL 302
Query: 453 HTNPSRRLTAAQALNHPWM 471
P R TA + L HPW+
Sbjct: 303 VKKPEDRATAEECLKHPWL 321
>BC023508-1|AAH23508.2| 414|Homo sapiens serine/threonine kinase
17a protein.
Length = 414
Score = 130 bits (314), Expect = 2e-29
Identities = 74/259 (28%), Positives = 139/259 (53%), Gaps = 15/259 (5%)
Query: 228 PLKLIGSGVYGKVM-LIRSNAGKQFVAKTVISQY--QTNSME---EYSTLRILRNTPNIV 281
P + +G G + V I+ ++GK+F AK + + Q ME E + L + ++ P ++
Sbjct: 63 PGRELGRGKFAVVRKCIKKDSGKEFAAKFMRKRRKGQDCRMEIIHEIAVLELAQDNPWVI 122
Query: 282 KLIECYSDGLNWVFVMENLWGGNLFDRF--KHHQCISERDIKIYLRQVCSGLQYIHNNGL 339
L E Y + V+E GG +FD+ + E+D++ +RQ+ G+ ++H +
Sbjct: 123 NLHEVYETASEMILVLEYAAGGEIFDQCVADREEAFKEKDVQRLMRQILEGVHFLHTRDV 182
Query: 340 IHFDIKPENVMCCSLNCL-NIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLTT 398
+H D+KP+N++ S + L +IKI+DFGL++ ++ + G VAPE+ S + ++
Sbjct: 183 VHLDLKPQNILLTSESPLGDIKIVDFGLSRILKNSEELREIMGTPEYVAPEILSYDPISM 242
Query: 399 AYDMWSVGILMGIGLLGYTPRIIGKRSR------RLSVVFTSQEYLCISGAALHFFGKCL 452
A DMWS+G+L + L G +P + + ++++ ++ +E+ +S +A+ F L
Sbjct: 243 ATDMWSIGVLTYVMLTGISPFLGNDKQETFLNISQMNLSYSEEEFDVLSESAVDFIRTLL 302
Query: 453 HTNPSRRLTAAQALNHPWM 471
P R TA + L HPW+
Sbjct: 303 VKKPEDRATAEECLKHPWL 321
>AB011420-1|BAA34126.1| 414|Homo sapiens DRAK1 protein.
Length = 414
Score = 130 bits (314), Expect = 2e-29
Identities = 74/259 (28%), Positives = 139/259 (53%), Gaps = 15/259 (5%)
Query: 228 PLKLIGSGVYGKVM-LIRSNAGKQFVAKTVISQY--QTNSME---EYSTLRILRNTPNIV 281
P + +G G + V I+ ++GK+F AK + + Q ME E + L + ++ P ++
Sbjct: 63 PGRELGRGKFAVVRKCIKKDSGKEFAAKFMRKRRKGQDCRMEIIHEIAVLELAQDNPWVI 122
Query: 282 KLIECYSDGLNWVFVMENLWGGNLFDRF--KHHQCISERDIKIYLRQVCSGLQYIHNNGL 339
L E Y + V+E GG +FD+ + E+D++ +RQ+ G+ ++H +
Sbjct: 123 NLHEVYETASEMILVLEYAAGGEIFDQCVADREEAFKEKDVQRLMRQILEGVHFLHTRDV 182
Query: 340 IHFDIKPENVMCCSLNCL-NIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLTT 398
+H D+KP+N++ S + L +IKI+DFGL++ ++ + G VAPE+ S + ++
Sbjct: 183 VHLDLKPQNILLTSESPLGDIKIVDFGLSRILKNSEELREIMGTPEYVAPEILSYDPISM 242
Query: 399 AYDMWSVGILMGIGLLGYTPRIIGKRSR------RLSVVFTSQEYLCISGAALHFFGKCL 452
A DMWS+G+L + L G +P + + ++++ ++ +E+ +S +A+ F L
Sbjct: 243 ATDMWSIGVLTYVMLTGISPFLGNDKQETFLNISQMNLSYSEEEFDVLSESAVDFIRTLL 302
Query: 453 HTNPSRRLTAAQALNHPWM 471
P R TA + L HPW+
Sbjct: 303 VKKPEDRATAEECLKHPWL 321
>BC032787-1|AAH32787.1| 476|Homo sapiens
calcium/calmodulin-dependent protein kinase IG protein.
Length = 476
Score = 130 bits (313), Expect = 2e-29
Identities = 82/266 (30%), Positives = 141/266 (53%), Gaps = 13/266 (4%)
Query: 217 KSLQNFYRDFLPLKLIGSGVYGKVMLIRSN-AGKQFVAKTVISQ--YQTNSME-EYSTLR 272
K N + F+ ++++GSG + +V L++ GK F K + ++ +S+E E + L+
Sbjct: 14 KQTTNIRKTFIFMEVLGSGAFSEVFLVKQRLTGKLFALKCIKKSPAFRDSSLENEIAVLK 73
Query: 273 ILRNTPNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQ 332
+++ NIV L + Y ++ VM+ + GG LFDR +E+D + ++QV S ++
Sbjct: 74 KIKHE-NIVTLEDIYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVK 132
Query: 333 YIHNNGLIHFDIKPENVMCCS-LNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELY 391
Y+H NG++H D+KPEN++ + I I DFGL+K ++ ++ G VAPE+
Sbjct: 133 YLHENGIVHRDLKPENLLYLTPEENSKIMITDFGLSKMEQNGI-MSTACGTPGYVAPEVL 191
Query: 392 SGNVLTTAYDMWSVGILMGIGLLGYTPRIIGKRSRRLSVV------FTSQEYLCISGAAL 445
+ + A D WS+G++ I L GY P S+ + F S + IS +A
Sbjct: 192 AQKPYSKAVDCWSIGVITYILLCGYPPFYEETESKLFEKIKEGYYEFESPFWDDISESAK 251
Query: 446 HFFGKCLHTNPSRRLTAAQALNHPWM 471
F L +P+ R T +AL+HPW+
Sbjct: 252 DFICHLLEKDPNERYTCEKALSHPWI 277
>AY212935-1|AAP29964.1| 460|Homo sapiens CLICK III protein.
Length = 460
Score = 130 bits (313), Expect = 2e-29
Identities = 82/266 (30%), Positives = 141/266 (53%), Gaps = 13/266 (4%)
Query: 217 KSLQNFYRDFLPLKLIGSGVYGKVMLIRSN-AGKQFVAKTVISQ--YQTNSME-EYSTLR 272
K N + F+ ++++GSG + +V L++ GK F K + ++ +S+E E + L+
Sbjct: 14 KQTTNIRKTFIFMEVLGSGAFSEVFLVKQRLTGKLFALKCIKKSPAFRDSSLENEIAVLK 73
Query: 273 ILRNTPNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQ 332
+++ NIV L + Y ++ VM+ + GG LFDR +E+D + ++QV S ++
Sbjct: 74 KIKHE-NIVTLEDIYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVK 132
Query: 333 YIHNNGLIHFDIKPENVMCCS-LNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELY 391
Y+H NG++H D+KPEN++ + I I DFGL+K ++ ++ G VAPE+
Sbjct: 133 YLHENGIVHRDLKPENLLYLTPEENSKIMITDFGLSKMEQNGI-MSTACGTPGYVAPEVL 191
Query: 392 SGNVLTTAYDMWSVGILMGIGLLGYTPRIIGKRSRRLSVV------FTSQEYLCISGAAL 445
+ + A D WS+G++ I L GY P S+ + F S + IS +A
Sbjct: 192 AQKPYSKAVDCWSIGVITYILLCGYPPFYEETESKLFEKIKEGYYEFESPFWDDISESAK 251
Query: 446 HFFGKCLHTNPSRRLTAAQALNHPWM 471
F L +P+ R T +AL+HPW+
Sbjct: 252 DFICHLLEKDPNERYTCEKALSHPWI 277
>AL049688-1|CAB41259.1| 481|Homo sapiens hypothetical protein
protein.
Length = 481
Score = 130 bits (313), Expect = 2e-29
Identities = 82/266 (30%), Positives = 141/266 (53%), Gaps = 13/266 (4%)
Query: 217 KSLQNFYRDFLPLKLIGSGVYGKVMLIRSN-AGKQFVAKTVISQ--YQTNSME-EYSTLR 272
K N + F+ ++++GSG + +V L++ GK F K + ++ +S+E E + L+
Sbjct: 19 KQTTNIRKTFIFMEVLGSGAFSEVFLVKQRLTGKLFALKCIKKSPAFRDSSLENEIAVLK 78
Query: 273 ILRNTPNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQ 332
+++ NIV L + Y ++ VM+ + GG LFDR +E+D + ++QV S ++
Sbjct: 79 KIKHE-NIVTLEDIYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVK 137
Query: 333 YIHNNGLIHFDIKPENVMCCS-LNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELY 391
Y+H NG++H D+KPEN++ + I I DFGL+K ++ ++ G VAPE+
Sbjct: 138 YLHENGIVHRDLKPENLLYLTPEENSKIMITDFGLSKMEQNGI-MSTACGTPGYVAPEVL 196
Query: 392 SGNVLTTAYDMWSVGILMGIGLLGYTPRIIGKRSRRLSVV------FTSQEYLCISGAAL 445
+ + A D WS+G++ I L GY P S+ + F S + IS +A
Sbjct: 197 AQKPYSKAVDCWSIGVITYILLCGYPPFYEETESKLFEKIKEGYYEFESPFWDDISESAK 256
Query: 446 HFFGKCLHTNPSRRLTAAQALNHPWM 471
F L +P+ R T +AL+HPW+
Sbjct: 257 DFICHLLEKDPNERYTCEKALSHPWI 282
>AL023754-3|CAI19991.1| 476|Homo sapiens
calcium/calmodulin-dependent protein kinase IG protein.
Length = 476
Score = 130 bits (313), Expect = 2e-29
Identities = 82/266 (30%), Positives = 141/266 (53%), Gaps = 13/266 (4%)
Query: 217 KSLQNFYRDFLPLKLIGSGVYGKVMLIRSN-AGKQFVAKTVISQ--YQTNSME-EYSTLR 272
K N + F+ ++++GSG + +V L++ GK F K + ++ +S+E E + L+
Sbjct: 14 KQTTNIRKTFIFMEVLGSGAFSEVFLVKQRLTGKLFALKCIKKSPAFRDSSLENEIAVLK 73
Query: 273 ILRNTPNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQ 332
+++ NIV L + Y ++ VM+ + GG LFDR +E+D + ++QV S ++
Sbjct: 74 KIKHE-NIVTLEDIYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVK 132
Query: 333 YIHNNGLIHFDIKPENVMCCS-LNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELY 391
Y+H NG++H D+KPEN++ + I I DFGL+K ++ ++ G VAPE+
Sbjct: 133 YLHENGIVHRDLKPENLLYLTPEENSKIMITDFGLSKMEQNGI-MSTACGTPGYVAPEVL 191
Query: 392 SGNVLTTAYDMWSVGILMGIGLLGYTPRIIGKRSRRLSVV------FTSQEYLCISGAAL 445
+ + A D WS+G++ I L GY P S+ + F S + IS +A
Sbjct: 192 AQKPYSKAVDCWSIGVITYILLCGYPPFYEETESKLFEKIKEGYYEFESPFWDDISESAK 251
Query: 446 HFFGKCLHTNPSRRLTAAQALNHPWM 471
F L +P+ R T +AL+HPW+
Sbjct: 252 DFICHLLEKDPNERYTCEKALSHPWI 277
>AF428261-1|AAL28100.1| 476|Homo sapiens
calcium/calmodulin-dependent protein kinase I gamma
protein.
Length = 476
Score = 130 bits (313), Expect = 2e-29
Identities = 82/266 (30%), Positives = 141/266 (53%), Gaps = 13/266 (4%)
Query: 217 KSLQNFYRDFLPLKLIGSGVYGKVMLIRSN-AGKQFVAKTVISQ--YQTNSME-EYSTLR 272
K N + F+ ++++GSG + +V L++ GK F K + ++ +S+E E + L+
Sbjct: 14 KQTTNIRKTFIFMEVLGSGAFSEVFLVKQRLTGKLFALKCIKKSPAFRDSSLENEIAVLK 73
Query: 273 ILRNTPNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQ 332
+++ NIV L + Y ++ VM+ + GG LFDR +E+D + ++QV S ++
Sbjct: 74 KIKHE-NIVTLEDIYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVK 132
Query: 333 YIHNNGLIHFDIKPENVMCCS-LNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELY 391
Y+H NG++H D+KPEN++ + I I DFGL+K ++ ++ G VAPE+
Sbjct: 133 YLHENGIVHRDLKPENLLYLTPEENSKIMITDFGLSKMEQNGI-MSTACGTPGYVAPEVL 191
Query: 392 SGNVLTTAYDMWSVGILMGIGLLGYTPRIIGKRSRRLSVV------FTSQEYLCISGAAL 445
+ + A D WS+G++ I L GY P S+ + F S + IS +A
Sbjct: 192 AQKPYSKAVDCWSIGVITYILLCGYPPFYEETESKLFEKIKEGYYEFESPFWDDISESAK 251
Query: 446 HFFGKCLHTNPSRRLTAAQALNHPWM 471
F L +P+ R T +AL+HPW+
Sbjct: 252 DFICHLLEKDPNERYTCEKALSHPWI 277
>CR542225-1|CAG47021.1| 372|Homo sapiens STK17B protein.
Length = 372
Score = 125 bits (301), Expect = 6e-28
Identities = 79/304 (25%), Positives = 155/304 (50%), Gaps = 22/304 (7%)
Query: 209 LITSPQYLKSLQNFYRDF-LPLKLIGSGVYGKV-MLIRSNAGKQFVAKTVISQYQTNS-- 264
L T+PQ ++NF + L K +G G + V I + G+++ AK + + +
Sbjct: 15 LTTTPQIPIKMENFNNFYILTSKELGRGKFAVVRQCISKSTGQEYAAKFLKKRRRGQDCR 74
Query: 265 ---MEEYSTLRILRNTPNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHH--QCISERD 319
+ E + L + ++ P ++ L E Y + + ++E GG +F + +SE D
Sbjct: 75 AEILHEIAVLELAKSCPRVINLHEVYENTSEIILILEYAAGGEIFSLCLPELAEMVSEND 134
Query: 320 IKIYLRQVCSGLQYIHNNGLIHFDIKPENVMCCSLNCL-NIKIIDFGLTKCARSRTPINR 378
+ ++Q+ G+ Y+H N ++H D+KP+N++ S+ L +IKI+DFG+++ +
Sbjct: 135 VIRLIKQILEGVHYLHQNNIVHLDLKPQNILLSSIYPLGDIKIVDFGMSRKIGHACELRE 194
Query: 379 NFGFFSSVAPELYSGNVLTTAYDMWSVGILMGIGLLGYTPRIIGKRSR-------RLSVV 431
G +APE+ + + +TTA DMW++GI+ + LL +T +G+ ++ +++V
Sbjct: 195 IMGTPEYLAPEILNYDPITTATDMWNIGIIAYM-LLTHTSPFVGEDNQETYLNISQVNVD 253
Query: 432 FTSQEYLCISGAALHFFGKCLHTNPSRRLTAAQALNHPWM----FDTCPHPLSWKKPSKN 487
++ + + +S A F L NP +R TA L+H W+ F+ HP S+
Sbjct: 254 YSEETFSSVSQLATDFIQSLLVKNPEKRPTAEICLSHSWLQQWDFENLFHPEETSSSSQT 313
Query: 488 RRYN 491
+ ++
Sbjct: 314 QDHS 317
>BC016040-1|AAH16040.1| 372|Homo sapiens serine/threonine kinase
17b protein.
Length = 372
Score = 124 bits (300), Expect = 8e-28
Identities = 79/304 (25%), Positives = 155/304 (50%), Gaps = 22/304 (7%)
Query: 209 LITSPQYLKSLQNFYRDF-LPLKLIGSGVYGKV-MLIRSNAGKQFVAKTVISQYQTNS-- 264
L T+PQ ++NF + L K +G G + V I + G+++ AK + + +
Sbjct: 15 LTTTPQIPIKMENFNNFYILTSKELGRGKFAVVRQCISKSTGQEYAAKFLKKRRRGQDCR 74
Query: 265 ---MEEYSTLRILRNTPNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHH--QCISERD 319
+ E + L + ++ P ++ L E Y + + ++E GG +F + +SE D
Sbjct: 75 AEILHEIAVLELAKSCPRVINLHEVYENTSEIILILEYAAGGEIFSLCLPELAEMVSEND 134
Query: 320 IKIYLRQVCSGLQYIHNNGLIHFDIKPENVMCCSLNCL-NIKIIDFGLTKCARSRTPINR 378
+ ++Q+ G+ Y+H N ++H D+KP+N++ S+ L +IKI+DFG+++ +
Sbjct: 135 VIRLIKQILEGVYYLHQNNIVHLDLKPQNILLSSIYPLGDIKIVDFGMSRKIGHACELRE 194
Query: 379 NFGFFSSVAPELYSGNVLTTAYDMWSVGILMGIGLLGYTPRIIGKRSR-------RLSVV 431
G +APE+ + + +TTA DMW++GI+ + LL +T +G+ ++ +++V
Sbjct: 195 IMGTPEYLAPEILNYDPITTATDMWNIGIIAYM-LLTHTSPFVGEDNQETYLNISQVNVD 253
Query: 432 FTSQEYLCISGAALHFFGKCLHTNPSRRLTAAQALNHPWM----FDTCPHPLSWKKPSKN 487
++ + + +S A F L NP +R TA L+H W+ F+ HP S+
Sbjct: 254 YSEETFSSVSQLATDFIQSLLVKNPEKRPTAEICLSHSWLQQWDFENLFHPEETSSSSQT 313
Query: 488 RRYN 491
+ ++
Sbjct: 314 QDHS 317
>AC114760-2|AAY14982.1| 372|Homo sapiens unknown protein.
Length = 372
Score = 124 bits (300), Expect = 8e-28
Identities = 79/304 (25%), Positives = 155/304 (50%), Gaps = 22/304 (7%)
Query: 209 LITSPQYLKSLQNFYRDF-LPLKLIGSGVYGKV-MLIRSNAGKQFVAKTVISQYQTNS-- 264
L T+PQ ++NF + L K +G G + V I + G+++ AK + + +
Sbjct: 15 LTTTPQIPIKMENFNNFYILTSKELGRGKFAVVRQCISKSTGQEYAAKFLKKRRRGQDCR 74
Query: 265 ---MEEYSTLRILRNTPNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHH--QCISERD 319
+ E + L + ++ P ++ L E Y + + ++E GG +F + +SE D
Sbjct: 75 AEILHEIAVLELAKSCPRVINLHEVYENTSEIILILEYAAGGEIFSLCLPELAEMVSEND 134
Query: 320 IKIYLRQVCSGLQYIHNNGLIHFDIKPENVMCCSLNCL-NIKIIDFGLTKCARSRTPINR 378
+ ++Q+ G+ Y+H N ++H D+KP+N++ S+ L +IKI+DFG+++ +
Sbjct: 135 VIRLIKQILEGVYYLHQNNIVHLDLKPQNILLSSIYPLGDIKIVDFGMSRKIGHACELRE 194
Query: 379 NFGFFSSVAPELYSGNVLTTAYDMWSVGILMGIGLLGYTPRIIGKRSR-------RLSVV 431
G +APE+ + + +TTA DMW++GI+ + LL +T +G+ ++ +++V
Sbjct: 195 IMGTPEYLAPEILNYDPITTATDMWNIGIIAYM-LLTHTSPFVGEDNQETYLNISQVNVD 253
Query: 432 FTSQEYLCISGAALHFFGKCLHTNPSRRLTAAQALNHPWM----FDTCPHPLSWKKPSKN 487
++ + + +S A F L NP +R TA L+H W+ F+ HP S+
Sbjct: 254 YSEETFSSVSQLATDFIQSLLVKNPEKRPTAEICLSHSWLQQWDFENLFHPEETSSSSQT 313
Query: 488 RRYN 491
+ ++
Sbjct: 314 QDHS 317
>AB011421-1|BAA34127.1| 372|Homo sapiens DRAK2 protein.
Length = 372
Score = 124 bits (300), Expect = 8e-28
Identities = 79/304 (25%), Positives = 155/304 (50%), Gaps = 22/304 (7%)
Query: 209 LITSPQYLKSLQNFYRDF-LPLKLIGSGVYGKV-MLIRSNAGKQFVAKTVISQYQTNS-- 264
L T+PQ ++NF + L K +G G + V I + G+++ AK + + +
Sbjct: 15 LTTTPQIPIKMENFNNFYILTSKELGRGKFAVVRQCISKSTGQEYAAKFLKKRRRGQDCR 74
Query: 265 ---MEEYSTLRILRNTPNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHH--QCISERD 319
+ E + L + ++ P ++ L E Y + + ++E GG +F + +SE D
Sbjct: 75 AEILHEIAVLELAKSCPRVINLHEVYENTSEIILILEYAAGGEIFSLCLPELAEMVSEND 134
Query: 320 IKIYLRQVCSGLQYIHNNGLIHFDIKPENVMCCSLNCL-NIKIIDFGLTKCARSRTPINR 378
+ ++Q+ G+ Y+H N ++H D+KP+N++ S+ L +IKI+DFG+++ +
Sbjct: 135 VIRLIKQILEGVYYLHQNNIVHLDLKPQNILLSSIYPLGDIKIVDFGMSRKIGHACELRE 194
Query: 379 NFGFFSSVAPELYSGNVLTTAYDMWSVGILMGIGLLGYTPRIIGKRSR-------RLSVV 431
G +APE+ + + +TTA DMW++GI+ + LL +T +G+ ++ +++V
Sbjct: 195 IMGTPEYLAPEILNYDPITTATDMWNIGIIAYM-LLTHTSPFVGEDNQETYLNISQVNVD 253
Query: 432 FTSQEYLCISGAALHFFGKCLHTNPSRRLTAAQALNHPWM----FDTCPHPLSWKKPSKN 487
++ + + +S A F L NP +R TA L+H W+ F+ HP S+
Sbjct: 254 YSEETFSSVSQLATDFIQSLLVKNPEKRPTAEICLSHSWLQQWDFENLFHPEETSSSSQT 313
Query: 488 RRYN 491
+ ++
Sbjct: 314 QDHS 317
>BC109097-1|AAI09098.2| 795|Homo sapiens MLCK protein protein.
Length = 795
Score = 124 bits (298), Expect = 1e-27
Identities = 72/254 (28%), Positives = 132/254 (51%), Gaps = 14/254 (5%)
Query: 230 KLIGSGVYGKV-MLIRSNAGKQFVAKTVISQYQTNSMEEYSTLRILRNTP--NIVKLIEC 286
+++G G +G+V + G AK + + + + + + I+ N+++L +
Sbjct: 495 EVLGGGRFGQVHRCTEKSTGLPLAAKIIKVKSAKDREDVKNEINIMNQLSHVNLIQLYDA 554
Query: 287 YSDGLNWVFVMENLWGGNLFDRF---KHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFD 343
+ + VME + GG LFDR K+H ++E D+ ++ RQ+C G+ Y+H + ++H D
Sbjct: 555 FESKHSCTLVMEYVDGGELFDRITDEKYH--LTELDVVLFTRQICEGVHYLHQHYILHLD 612
Query: 344 IKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLTTAYDMW 403
+KPEN++C + IKIIDFGL + + R + NFG +APE+ + ++ DMW
Sbjct: 613 LKPENILCVNQTGHQIKIIDFGLARRYKPREKLKVNFGTPEFLAPEVVNYEFVSFPTDMW 672
Query: 404 SVGILMGIGLLGYTPRIIGKRSRRLSVV------FTSQEYLCISGAALHFFGKCLHTNPS 457
SVG++ + L G +P + + ++ + F + + +S A F + L S
Sbjct: 673 SVGVITYMLLSGLSPFLGETDAETMNFIVNCSWDFDADTFEGLSEEAKDFVSRLLVKEKS 732
Query: 458 RRLTAAQALNHPWM 471
R++A Q L H W+
Sbjct: 733 CRMSATQCLKHEWL 746
>AJ247087-1|CAC42766.1| 795|Homo sapiens myosin light chain kinase
(MLCK) protein.
Length = 795
Score = 124 bits (298), Expect = 1e-27
Identities = 72/254 (28%), Positives = 132/254 (51%), Gaps = 14/254 (5%)
Query: 230 KLIGSGVYGKV-MLIRSNAGKQFVAKTVISQYQTNSMEEYSTLRILRNTP--NIVKLIEC 286
+++G G +G+V + G AK + + + + + + I+ N+++L +
Sbjct: 495 EVLGGGRFGQVHRCTEKSTGLPLAAKIIKVKSAKDREDVKNEINIMNQLSHVNLIQLYDA 554
Query: 287 YSDGLNWVFVMENLWGGNLFDRF---KHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFD 343
+ + VME + GG LFDR K+H ++E D+ ++ RQ+C G+ Y+H + ++H D
Sbjct: 555 FESKHSCTLVMEYVDGGELFDRITDEKYH--LTELDVVLFTRQICEGVHYLHQHYILHLD 612
Query: 344 IKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLTTAYDMW 403
+KPEN++C + IKIIDFGL + + R + NFG +APE+ + ++ DMW
Sbjct: 613 LKPENILCVNQTGHQIKIIDFGLARRYKPREKLKVNFGTPEFLAPEVVNYEFVSFPTDMW 672
Query: 404 SVGILMGIGLLGYTPRIIGKRSRRLSVV------FTSQEYLCISGAALHFFGKCLHTNPS 457
SVG++ + L G +P + + ++ + F + + +S A F + L S
Sbjct: 673 SVGVITYMLLSGLSPFLGETDAETMNFIVNCSWDFDADTFEGLSEEAKDFVSRLLVKEKS 732
Query: 458 RRLTAAQALNHPWM 471
R++A Q L H W+
Sbjct: 733 CRMSATQCLKHEWL 746
>CR542210-1|CAG47006.1| 372|Homo sapiens STK17B protein.
Length = 372
Score = 122 bits (293), Expect = 6e-27
Identities = 78/304 (25%), Positives = 154/304 (50%), Gaps = 22/304 (7%)
Query: 209 LITSPQYLKSLQNFYRDF-LPLKLIGSGVYGKV-MLIRSNAGKQFVAKTVISQYQTNS-- 264
L T+PQ ++NF + L K +G G + V I + G+++ AK + + +
Sbjct: 15 LTTTPQIPIKMENFNNFYILTSKELGRGKFAVVRQCISKSTGQEYAAKFLKKRRRGQDCR 74
Query: 265 ---MEEYSTLRILRNTPNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHH--QCISERD 319
+ E + L + ++ P ++ L E Y + + ++E GG +F + +SE D
Sbjct: 75 AEILHEIAVLELAKSCPRVINLHEVYENTSEIILILEYAAGGEIFSLCLPELAEMVSEND 134
Query: 320 IKIYLRQVCSGLQYIHNNGLIHFDIKPENVMCCSLNCL-NIKIIDFGLTKCARSRTPINR 378
+ ++Q+ G+ Y+H N ++H D+KP+N++ S+ L +IKI+DFG+++ +
Sbjct: 135 VIRLIKQILEGVYYLHQNNIVHLDLKPQNILLSSIYPLGDIKIVDFGMSRKIGHACELRE 194
Query: 379 NFGFFSSVAPELYSGNVLTTAYDMWSVGILMGIGLLGYTPRIIGKRSR-------RLSVV 431
G +APE+ + + +TTA DMW++GI+ + LL +T +G+ ++ +++V
Sbjct: 195 IMGTPEYLAPEILNYDPITTATDMWNIGIIAYM-LLTHTSPFVGEDNQETYLNISQVNVD 253
Query: 432 FTSQEYLCISGAALHFFGKCLHTNPSRRLTAAQALNHPWM----FDTCPHPLSWKKPSKN 487
++ + + +S A F L NP + TA L+H W+ F+ HP S+
Sbjct: 254 YSEETFSSVSQLATDFIQSLLVKNPEKGPTAEICLSHSWLQQWDFENLFHPEETSSSSQT 313
Query: 488 RRYN 491
+ ++
Sbjct: 314 QDHS 317
>BC126432-1|AAI26433.1| 454|Homo sapiens death-associated protein
kinase 3 protein.
Length = 454
Score = 121 bits (292), Expect = 8e-27
Identities = 78/258 (30%), Positives = 130/258 (50%), Gaps = 19/258 (7%)
Query: 232 IGSGVYGKVMLIRSNA-GKQFVAKTVISQYQTNSME---------EYSTLRILRNTPNIV 281
+GSG + V R GK++ AK + + ++S E + LR +R+ PNI+
Sbjct: 19 LGSGQFAIVRKCRQKGTGKEYAAKFIKKRRLSSSRRGVSREEIEREVNILREIRH-PNII 77
Query: 282 KLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIH 341
L + + + + V ++E + GG LFD + ++E + +L+Q+ G+ Y+H+ + H
Sbjct: 78 TLHDIFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQILDGVHYLHSKRIAH 137
Query: 342 FDIKPENVMCCSLNCLN--IKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLTTA 399
FD+KPEN+M N N IK+IDFG+ + FG VAPE+ + L
Sbjct: 138 FDLKPENIMLLDKNVPNPRIKLIDFGIAHKIEAGNEFKNIFGTPEFVAPEIVNYEPLGLE 197
Query: 400 YDMWSVGILMGIGLLGYTPRIIGKRSRRLSVV------FTSQEYLCISGAALHFFGKCLH 453
DMWS+G++ I L G +P + + L+ + F + + S A F + L
Sbjct: 198 ADMWSIGVITYILLSGASPFLGETKQETLTNISAVNYDFDEEYFSNTSELAKDFIRRLLV 257
Query: 454 TNPSRRLTAAQALNHPWM 471
+P RR+T AQ+L H W+
Sbjct: 258 KDPKRRMTIAQSLEHSWI 275
>BC126430-1|AAI26431.1| 454|Homo sapiens death-associated protein
kinase 3 protein.
Length = 454
Score = 121 bits (292), Expect = 8e-27
Identities = 78/258 (30%), Positives = 130/258 (50%), Gaps = 19/258 (7%)
Query: 232 IGSGVYGKVMLIRSNA-GKQFVAKTVISQYQTNSME---------EYSTLRILRNTPNIV 281
+GSG + V R GK++ AK + + ++S E + LR +R+ PNI+
Sbjct: 19 LGSGQFAIVRKCRQKGTGKEYAAKFIKKRRLSSSRRGVSREEIEREVNILREIRH-PNII 77
Query: 282 KLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIH 341
L + + + + V ++E + GG LFD + ++E + +L+Q+ G+ Y+H+ + H
Sbjct: 78 TLHDIFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQILDGVHYLHSKRIAH 137
Query: 342 FDIKPENVMCCSLNCLN--IKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLTTA 399
FD+KPEN+M N N IK+IDFG+ + FG VAPE+ + L
Sbjct: 138 FDLKPENIMLLDKNVPNPRIKLIDFGIAHKIEAGNEFKNIFGTPEFVAPEIVNYEPLGLE 197
Query: 400 YDMWSVGILMGIGLLGYTPRIIGKRSRRLSVV------FTSQEYLCISGAALHFFGKCLH 453
DMWS+G++ I L G +P + + L+ + F + + S A F + L
Sbjct: 198 ADMWSIGVITYILLSGASPFLGETKQETLTNISAVNYDFDEEYFSNTSELAKDFIRRLLV 257
Query: 454 TNPSRRLTAAQALNHPWM 471
+P RR+T AQ+L H W+
Sbjct: 258 KDPKRRMTIAQSLEHSWI 275
>AB022341-1|BAA81746.1| 454|Homo sapiens ZIP kinase protein.
Length = 454
Score = 121 bits (292), Expect = 8e-27
Identities = 78/258 (30%), Positives = 130/258 (50%), Gaps = 19/258 (7%)
Query: 232 IGSGVYGKVMLIRSNA-GKQFVAKTVISQYQTNSME---------EYSTLRILRNTPNIV 281
+GSG + V R GK++ AK + + ++S E + LR +R+ PNI+
Sbjct: 19 LGSGQFAIVRKCRQKGTGKEYAAKFIKKRRLSSSRRGVSREEIEREVNILREIRH-PNII 77
Query: 282 KLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIH 341
L + + + + V ++E + GG LFD + ++E + +L+Q+ G+ Y+H+ + H
Sbjct: 78 TLHDIFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQILDGVHYLHSKRIAH 137
Query: 342 FDIKPENVMCCSLNCLN--IKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLTTA 399
FD+KPEN+M N N IK+IDFG+ + FG VAPE+ + L
Sbjct: 138 FDLKPENIMLLDKNVPNPRIKLIDFGIAHKIEAGNEFKNIFGTPEFVAPEIVNYEPLGLE 197
Query: 400 YDMWSVGILMGIGLLGYTPRIIGKRSRRLSVV------FTSQEYLCISGAALHFFGKCLH 453
DMWS+G++ I L G +P + + L+ + F + + S A F + L
Sbjct: 198 ADMWSIGVITYILLSGASPFLGETKQETLTNISAVNYDFDEEYFSNTSELAKDFIRRLLV 257
Query: 454 TNPSRRLTAAQALNHPWM 471
+P RR+T AQ+L H W+
Sbjct: 258 KDPKRRMTIAQSLEHSWI 275
>AB007144-1|BAA24955.1| 454|Homo sapiens ZIP-kinase protein.
Length = 454
Score = 121 bits (292), Expect = 8e-27
Identities = 78/258 (30%), Positives = 130/258 (50%), Gaps = 19/258 (7%)
Query: 232 IGSGVYGKVMLIRSNA-GKQFVAKTVISQYQTNSME---------EYSTLRILRNTPNIV 281
+GSG + V R GK++ AK + + ++S E + LR +R+ PNI+
Sbjct: 19 LGSGQFAIVRKCRQKGTGKEYAAKFIKKRRLSSSRRGVSREEIEREVNILREIRH-PNII 77
Query: 282 KLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIH 341
L + + + + V ++E + GG LFD + ++E + +L+Q+ G+ Y+H+ + H
Sbjct: 78 TLHDIFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQILDGVHYLHSKRIAH 137
Query: 342 FDIKPENVMCCSLNCLN--IKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLTTA 399
FD+KPEN+M N N IK+IDFG+ + FG VAPE+ + L
Sbjct: 138 FDLKPENIMLLDKNVPNPRIKLIDFGIAHKIEAGNEFKNIFGTPEFVAPEIVNYEPLGLE 197
Query: 400 YDMWSVGILMGIGLLGYTPRIIGKRSRRLSVV------FTSQEYLCISGAALHFFGKCLH 453
DMWS+G++ I L G +P + + L+ + F + + S A F + L
Sbjct: 198 ADMWSIGVITYILLSGASPFLGETKQETLTNISAVNYDFDEEYFSNTSELAKDFIRRLLV 257
Query: 454 TNPSRRLTAAQALNHPWM 471
+P RR+T AQ+L H W+
Sbjct: 258 KDPKRRMTIAQSLEHSWI 275
>L41816-1|AAA99458.1| 370|Homo sapiens cam kinase I protein.
Length = 370
Score = 120 bits (288), Expect = 2e-26
Identities = 79/253 (31%), Positives = 131/253 (51%), Gaps = 13/253 (5%)
Query: 231 LIGSGVYGKVMLIRSNAGKQFVAKTVISQY----QTNSME-EYSTLRILRNTPNIVKLIE 285
++G+G + +V+L ++ VA I++ + SME E + L +++ PNIV L +
Sbjct: 25 VLGTGAFSEVILAEDKRTQKLVAIKCIAKEALEGKEGSMENEIAVLHKIKH-PNIVALDD 83
Query: 286 CYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFDIK 345
Y G + +M+ + GG LFDR +ERD + QV ++Y+H+ G++H D+K
Sbjct: 84 IYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLGIVHRDLK 143
Query: 346 PENVMCCSLN-CLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLTTAYDMWS 404
PEN++ SL+ I I DFGL+K + ++ G VAPE+ + + A D WS
Sbjct: 144 PENLLYYSLDEDSKIMISDFGLSKMEDPGSVLSTACGTPGYVAPEVLAQKPYSKAVDCWS 203
Query: 405 VGILMGIGLLGYTP------RIIGKRSRRLSVVFTSQEYLCISGAALHFFGKCLHTNPSR 458
+G++ I L GY P + ++ + F S + IS +A F + +P +
Sbjct: 204 IGVIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDISDSAKDFIRHLMEKDPEK 263
Query: 459 RLTAAQALNHPWM 471
R T QAL HPW+
Sbjct: 264 RFTCEQALQHPWI 276
>BC106755-1|AAI06756.1| 370|Homo sapiens
calcium/calmodulin-dependent protein kinase I protein.
Length = 370
Score = 120 bits (288), Expect = 2e-26
Identities = 79/253 (31%), Positives = 131/253 (51%), Gaps = 13/253 (5%)
Query: 231 LIGSGVYGKVMLIRSNAGKQFVAKTVISQY----QTNSME-EYSTLRILRNTPNIVKLIE 285
++G+G + +V+L ++ VA I++ + SME E + L +++ PNIV L +
Sbjct: 25 VLGTGAFSEVILAEDKRTQKLVAIKCIAKEALEGKEGSMENEIAVLHKIKH-PNIVALDD 83
Query: 286 CYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFDIK 345
Y G + +M+ + GG LFDR +ERD + QV ++Y+H+ G++H D+K
Sbjct: 84 IYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLGIVHRDLK 143
Query: 346 PENVMCCSLN-CLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLTTAYDMWS 404
PEN++ SL+ I I DFGL+K + ++ G VAPE+ + + A D WS
Sbjct: 144 PENLLYYSLDEDSKIMISDFGLSKMEDPGSVLSTACGTPGYVAPEVLAQKPYSKAVDCWS 203
Query: 405 VGILMGIGLLGYTP------RIIGKRSRRLSVVFTSQEYLCISGAALHFFGKCLHTNPSR 458
+G++ I L GY P + ++ + F S + IS +A F + +P +
Sbjct: 204 IGVIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDISDSAKDFIRHLMEKDPEK 263
Query: 459 RLTAAQALNHPWM 471
R T QAL HPW+
Sbjct: 264 RFTCEQALQHPWI 276
>BC106754-1|AAI06755.1| 370|Homo sapiens
calcium/calmodulin-dependent protein kinase I protein.
Length = 370
Score = 120 bits (288), Expect = 2e-26
Identities = 79/253 (31%), Positives = 131/253 (51%), Gaps = 13/253 (5%)
Query: 231 LIGSGVYGKVMLIRSNAGKQFVAKTVISQY----QTNSME-EYSTLRILRNTPNIVKLIE 285
++G+G + +V+L ++ VA I++ + SME E + L +++ PNIV L +
Sbjct: 25 VLGTGAFSEVILAEDKRTQKLVAIKCIAKEALEGKEGSMENEIAVLHKIKH-PNIVALDD 83
Query: 286 CYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFDIK 345
Y G + +M+ + GG LFDR +ERD + QV ++Y+H+ G++H D+K
Sbjct: 84 IYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLGIVHRDLK 143
Query: 346 PENVMCCSLN-CLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLTTAYDMWS 404
PEN++ SL+ I I DFGL+K + ++ G VAPE+ + + A D WS
Sbjct: 144 PENLLYYSLDEDSKIMISDFGLSKMEDPGSVLSTACGTPGYVAPEVLAQKPYSKAVDCWS 203
Query: 405 VGILMGIGLLGYTP------RIIGKRSRRLSVVFTSQEYLCISGAALHFFGKCLHTNPSR 458
+G++ I L GY P + ++ + F S + IS +A F + +P +
Sbjct: 204 IGVIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDISDSAKDFIRHLMEKDPEK 263
Query: 459 RLTAAQALNHPWM 471
R T QAL HPW+
Sbjct: 264 RFTCEQALQHPWI 276
>X90568-1|CAA62188.1|26926|Homo sapiens titin protein.
Length = 26926
Score = 117 bits (282), Expect = 1e-25
Identities = 79/264 (29%), Positives = 134/264 (50%), Gaps = 11/264 (4%)
Query: 218 SLQNFYRDFLPLKLIGSGVYGKV-MLIRSNAGKQFVAK--TVISQYQTNSMEEYSTLRIL 274
S + Y ++ + +G G +G V + +++ K ++AK V Q +E S L I
Sbjct: 24746 STKELYEKYMIAEDLGRGEFGIVHRCVETSSKKTYMAKFVKVKGTDQVLVKKEISILNIA 24805
Query: 275 RNTPNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQC-ISERDIKIYLRQVCSGLQY 333
R+ NI+ L E + V + E + G ++F+R ++ER+I Y+ QVC LQ+
Sbjct: 24806 RHR-NILHLHESFESMEELVMIFEFISGLDIFERINTSAFELNEREIVSYVHQVCEALQF 24864
Query: 334 IHNNGLIHFDIKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSG 393
+H++ + HFDI+PEN++ + IKII+FG + + F APE++
Sbjct: 24865 LHSHNIGHFDIRPENIIYQTRRSSTIKIIEFGQARQLKPGDNFRLLFTAPEYYAPEVHQH 24924
Query: 394 NVLTTAYDMWSVGILMGIGLLGYTPRI------IGKRSRRLSVVFTSQEYLCISGAALHF 447
+V++TA DMWS+G L+ + L G P + I + F + + IS A+ F
Sbjct: 24925 DVVSTATDMWSLGTLVYVLLSGINPFLAETNQQIIENIMNAEYTFDEEAFKEISIEAMDF 24984
Query: 448 FGKCLHTNPSRRLTAAQALNHPWM 471
+ L R+TA++AL HPW+
Sbjct: 24985 VDRLLVKERKSRMTASEALQHPWL 25008
>X69490-1|CAA49245.1| 4650|Homo sapiens titin protein.
Length = 4650
Score = 117 bits (282), Expect = 1e-25
Identities = 79/264 (29%), Positives = 134/264 (50%), Gaps = 11/264 (4%)
Query: 218 SLQNFYRDFLPLKLIGSGVYGKV-MLIRSNAGKQFVAK--TVISQYQTNSMEEYSTLRIL 274
S + Y ++ + +G G +G V + +++ K ++AK V Q +E S L I
Sbjct: 2470 STKELYEKYMIAEDLGRGEFGIVHRCVETSSKKTYMAKFVKVKGTDQVLVKKEISILNIA 2529
Query: 275 RNTPNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQC-ISERDIKIYLRQVCSGLQY 333
R+ NI+ L E + V + E + G ++F+R ++ER+I Y+ QVC LQ+
Sbjct: 2530 RHR-NILHLHESFESMEELVMIFEFISGLDIFERINTSAFELNEREIVSYVHQVCEALQF 2588
Query: 334 IHNNGLIHFDIKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSG 393
+H++ + HFDI+PEN++ + IKII+FG + + F APE++
Sbjct: 2589 LHSHNIGHFDIRPENIIYQTRRSSTIKIIEFGQARQLKPGDNFRLLFTAPEYYAPEVHQH 2648
Query: 394 NVLTTAYDMWSVGILMGIGLLGYTPRI------IGKRSRRLSVVFTSQEYLCISGAALHF 447
+V++TA DMWS+G L+ + L G P + I + F + + IS A+ F
Sbjct: 2649 DVVSTATDMWSLGTLVYVLLSGINPFLAETNQQIIENIMNAEYTFDEEAFKEISIEAMDF 2708
Query: 448 FGKCLHTNPSRRLTAAQALNHPWM 471
+ L R+TA++AL HPW+
Sbjct: 2709 VDRLLVKERKSRMTASEALQHPWL 2732
>X64697-1|CAA45938.1| 3100|Homo sapiens titin protein.
Length = 3100
Score = 117 bits (282), Expect = 1e-25
Identities = 79/264 (29%), Positives = 134/264 (50%), Gaps = 11/264 (4%)
Query: 218 SLQNFYRDFLPLKLIGSGVYGKV-MLIRSNAGKQFVAK--TVISQYQTNSMEEYSTLRIL 274
S + Y ++ + +G G +G V + +++ K ++AK V Q +E S L I
Sbjct: 2470 STKELYEKYMIAEDLGRGEFGIVHRCVETSSKKTYMAKFVKVKGTDQVLVKKEISILNIA 2529
Query: 275 RNTPNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQC-ISERDIKIYLRQVCSGLQY 333
R+ NI+ L E + V + E + G ++F+R ++ER+I Y+ QVC LQ+
Sbjct: 2530 RHR-NILHLHESFESMEELVMIFEFISGLDIFERINTSAFELNEREIVSYVHQVCEALQF 2588
Query: 334 IHNNGLIHFDIKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSG 393
+H++ + HFDI+PEN++ + IKII+FG + + F APE++
Sbjct: 2589 LHSHNIGHFDIRPENIIYQTRRSSTIKIIEFGQARQLKPGDNFRLLFTAPEYYAPEVHQH 2648
Query: 394 NVLTTAYDMWSVGILMGIGLLGYTPRI------IGKRSRRLSVVFTSQEYLCISGAALHF 447
+V++TA DMWS+G L+ + L G P + I + F + + IS A+ F
Sbjct: 2649 DVVSTATDMWSLGTLVYVLLSGINPFLAETNQQIIENIMNAEYTFDEEAFKEISIEAMDF 2708
Query: 448 FGKCLHTNPSRRLTAAQALNHPWM 471
+ L R+TA++AL HPW+
Sbjct: 2709 VDRLLVKERKSRMTASEALQHPWL 2732
>BC035745-1|AAH35745.1| 385|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 385
Score = 117 bits (282), Expect = 1e-25
Identities = 82/273 (30%), Positives = 135/273 (49%), Gaps = 13/273 (4%)
Query: 211 TSPQYLKSLQNFYRDFLPLKLIGSGVYGKVMLIRSNA-GKQFVAKTVISQY---QTNSME 266
+S + K ++ + F + +G+G + +V+L A GK F K + + + +S+E
Sbjct: 8 SSSSWKKQAEDIKKIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKESSIE 67
Query: 267 -EYSTLRILRNTPNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLR 325
E + LR +++ NIV L + Y + VM+ + GG LFDR +E+D +R
Sbjct: 68 NEIAVLRKIKHE-NIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIR 126
Query: 326 QVCSGLQYIHNNGLIHFDIKPENVMCCSLN-CLNIKIIDFGLTKCARSRTPINRNFGFFS 384
QV + Y+H G++H D+KPEN++ S + I I DFGL+K ++ G
Sbjct: 127 QVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGDVMSTACGTPG 186
Query: 385 SVAPELYSGNVLTTAYDMWSVGILMGIGLLGYTPRIIGKRSRRLSVV------FTSQEYL 438
VAPE+ + + A D WS+G++ I L GY P S+ + F S +
Sbjct: 187 YVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWD 246
Query: 439 CISGAALHFFGKCLHTNPSRRLTAAQALNHPWM 471
IS +A F + +P++R T QA HPW+
Sbjct: 247 DISDSAKDFIRNLMEKDPNKRYTCEQAARHPWI 279
>AL731559-2|CAI14675.1| 385|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 385
Score = 117 bits (282), Expect = 1e-25
Identities = 82/273 (30%), Positives = 135/273 (49%), Gaps = 13/273 (4%)
Query: 211 TSPQYLKSLQNFYRDFLPLKLIGSGVYGKVMLIRSNA-GKQFVAKTVISQY---QTNSME 266
+S + K ++ + F + +G+G + +V+L A GK F K + + + +S+E
Sbjct: 8 SSSSWKKQAEDIKKIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKESSIE 67
Query: 267 -EYSTLRILRNTPNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLR 325
E + LR +++ NIV L + Y + VM+ + GG LFDR +E+D +R
Sbjct: 68 NEIAVLRKIKHE-NIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIR 126
Query: 326 QVCSGLQYIHNNGLIHFDIKPENVMCCSLN-CLNIKIIDFGLTKCARSRTPINRNFGFFS 384
QV + Y+H G++H D+KPEN++ S + I I DFGL+K ++ G
Sbjct: 127 QVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGDVMSTACGTPG 186
Query: 385 SVAPELYSGNVLTTAYDMWSVGILMGIGLLGYTPRIIGKRSRRLSVV------FTSQEYL 438
VAPE+ + + A D WS+G++ I L GY P S+ + F S +
Sbjct: 187 YVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWD 246
Query: 439 CISGAALHFFGKCLHTNPSRRLTAAQALNHPWM 471
IS +A F + +P++R T QA HPW+
Sbjct: 247 DISDSAKDFIRNLMEKDPNKRYTCEQAARHPWI 279
>AL731559-1|CAI14674.1| 357|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 357
Score = 117 bits (282), Expect = 1e-25
Identities = 82/273 (30%), Positives = 135/273 (49%), Gaps = 13/273 (4%)
Query: 211 TSPQYLKSLQNFYRDFLPLKLIGSGVYGKVMLIRSNA-GKQFVAKTVISQY---QTNSME 266
+S + K ++ + F + +G+G + +V+L A GK F K + + + +S+E
Sbjct: 8 SSSSWKKQAEDIKKIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKESSIE 67
Query: 267 -EYSTLRILRNTPNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLR 325
E + LR +++ NIV L + Y + VM+ + GG LFDR +E+D +R
Sbjct: 68 NEIAVLRKIKHE-NIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIR 126
Query: 326 QVCSGLQYIHNNGLIHFDIKPENVMCCSLN-CLNIKIIDFGLTKCARSRTPINRNFGFFS 384
QV + Y+H G++H D+KPEN++ S + I I DFGL+K ++ G
Sbjct: 127 QVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGDVMSTACGTPG 186
Query: 385 SVAPELYSGNVLTTAYDMWSVGILMGIGLLGYTPRIIGKRSRRLSVV------FTSQEYL 438
VAPE+ + + A D WS+G++ I L GY P S+ + F S +
Sbjct: 187 YVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWD 246
Query: 439 CISGAALHFFGKCLHTNPSRRLTAAQALNHPWM 471
IS +A F + +P++R T QA HPW+
Sbjct: 247 DISDSAKDFIRNLMEKDPNKRYTCEQAARHPWI 279
>AL512783-2|CAH74036.1| 385|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 385
Score = 117 bits (282), Expect = 1e-25
Identities = 82/273 (30%), Positives = 135/273 (49%), Gaps = 13/273 (4%)
Query: 211 TSPQYLKSLQNFYRDFLPLKLIGSGVYGKVMLIRSNA-GKQFVAKTVISQY---QTNSME 266
+S + K ++ + F + +G+G + +V+L A GK F K + + + +S+E
Sbjct: 8 SSSSWKKQAEDIKKIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKESSIE 67
Query: 267 -EYSTLRILRNTPNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLR 325
E + LR +++ NIV L + Y + VM+ + GG LFDR +E+D +R
Sbjct: 68 NEIAVLRKIKHE-NIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIR 126
Query: 326 QVCSGLQYIHNNGLIHFDIKPENVMCCSLN-CLNIKIIDFGLTKCARSRTPINRNFGFFS 384
QV + Y+H G++H D+KPEN++ S + I I DFGL+K ++ G
Sbjct: 127 QVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGDVMSTACGTPG 186
Query: 385 SVAPELYSGNVLTTAYDMWSVGILMGIGLLGYTPRIIGKRSRRLSVV------FTSQEYL 438
VAPE+ + + A D WS+G++ I L GY P S+ + F S +
Sbjct: 187 YVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWD 246
Query: 439 CISGAALHFFGKCLHTNPSRRLTAAQALNHPWM 471
IS +A F + +P++R T QA HPW+
Sbjct: 247 DISDSAKDFIRNLMEKDPNKRYTCEQAARHPWI 279
>AL512783-1|CAH74035.1| 357|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 357
Score = 117 bits (282), Expect = 1e-25
Identities = 82/273 (30%), Positives = 135/273 (49%), Gaps = 13/273 (4%)
Query: 211 TSPQYLKSLQNFYRDFLPLKLIGSGVYGKVMLIRSNA-GKQFVAKTVISQY---QTNSME 266
+S + K ++ + F + +G+G + +V+L A GK F K + + + +S+E
Sbjct: 8 SSSSWKKQAEDIKKIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKESSIE 67
Query: 267 -EYSTLRILRNTPNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLR 325
E + LR +++ NIV L + Y + VM+ + GG LFDR +E+D +R
Sbjct: 68 NEIAVLRKIKHE-NIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIR 126
Query: 326 QVCSGLQYIHNNGLIHFDIKPENVMCCSLN-CLNIKIIDFGLTKCARSRTPINRNFGFFS 384
QV + Y+H G++H D+KPEN++ S + I I DFGL+K ++ G
Sbjct: 127 QVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGDVMSTACGTPG 186
Query: 385 SVAPELYSGNVLTTAYDMWSVGILMGIGLLGYTPRIIGKRSRRLSVV------FTSQEYL 438
VAPE+ + + A D WS+G++ I L GY P S+ + F S +
Sbjct: 187 YVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWD 246
Query: 439 CISGAALHFFGKCLHTNPSRRLTAAQALNHPWM 471
IS +A F + +P++R T QA HPW+
Sbjct: 247 DISDSAKDFIRNLMEKDPNKRYTCEQAARHPWI 279
>AL512284-2|CAH71694.1| 385|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 385
Score = 117 bits (282), Expect = 1e-25
Identities = 82/273 (30%), Positives = 135/273 (49%), Gaps = 13/273 (4%)
Query: 211 TSPQYLKSLQNFYRDFLPLKLIGSGVYGKVMLIRSNA-GKQFVAKTVISQY---QTNSME 266
+S + K ++ + F + +G+G + +V+L A GK F K + + + +S+E
Sbjct: 8 SSSSWKKQAEDIKKIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKESSIE 67
Query: 267 -EYSTLRILRNTPNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLR 325
E + LR +++ NIV L + Y + VM+ + GG LFDR +E+D +R
Sbjct: 68 NEIAVLRKIKHE-NIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIR 126
Query: 326 QVCSGLQYIHNNGLIHFDIKPENVMCCSLN-CLNIKIIDFGLTKCARSRTPINRNFGFFS 384
QV + Y+H G++H D+KPEN++ S + I I DFGL+K ++ G
Sbjct: 127 QVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGDVMSTACGTPG 186
Query: 385 SVAPELYSGNVLTTAYDMWSVGILMGIGLLGYTPRIIGKRSRRLSVV------FTSQEYL 438
VAPE+ + + A D WS+G++ I L GY P S+ + F S +
Sbjct: 187 YVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWD 246
Query: 439 CISGAALHFFGKCLHTNPSRRLTAAQALNHPWM 471
IS +A F + +P++R T QA HPW+
Sbjct: 247 DISDSAKDFIRNLMEKDPNKRYTCEQAARHPWI 279
>AL512284-1|CAH71693.1| 357|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 357
Score = 117 bits (282), Expect = 1e-25
Identities = 82/273 (30%), Positives = 135/273 (49%), Gaps = 13/273 (4%)
Query: 211 TSPQYLKSLQNFYRDFLPLKLIGSGVYGKVMLIRSNA-GKQFVAKTVISQY---QTNSME 266
+S + K ++ + F + +G+G + +V+L A GK F K + + + +S+E
Sbjct: 8 SSSSWKKQAEDIKKIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKESSIE 67
Query: 267 -EYSTLRILRNTPNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLR 325
E + LR +++ NIV L + Y + VM+ + GG LFDR +E+D +R
Sbjct: 68 NEIAVLRKIKHE-NIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIR 126
Query: 326 QVCSGLQYIHNNGLIHFDIKPENVMCCSLN-CLNIKIIDFGLTKCARSRTPINRNFGFFS 384
QV + Y+H G++H D+KPEN++ S + I I DFGL+K ++ G
Sbjct: 127 QVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGDVMSTACGTPG 186
Query: 385 SVAPELYSGNVLTTAYDMWSVGILMGIGLLGYTPRIIGKRSRRLSVV------FTSQEYL 438
VAPE+ + + A D WS+G++ I L GY P S+ + F S +
Sbjct: 187 YVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWD 246
Query: 439 CISGAALHFFGKCLHTNPSRRLTAAQALNHPWM 471
IS +A F + +P++R T QA HPW+
Sbjct: 247 DISDSAKDFIRNLMEKDPNKRYTCEQAARHPWI 279
>AL391314-2|CAI14410.1| 385|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 385
Score = 117 bits (282), Expect = 1e-25
Identities = 82/273 (30%), Positives = 135/273 (49%), Gaps = 13/273 (4%)
Query: 211 TSPQYLKSLQNFYRDFLPLKLIGSGVYGKVMLIRSNA-GKQFVAKTVISQY---QTNSME 266
+S + K ++ + F + +G+G + +V+L A GK F K + + + +S+E
Sbjct: 8 SSSSWKKQAEDIKKIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKESSIE 67
Query: 267 -EYSTLRILRNTPNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLR 325
E + LR +++ NIV L + Y + VM+ + GG LFDR +E+D +R
Sbjct: 68 NEIAVLRKIKHE-NIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIR 126
Query: 326 QVCSGLQYIHNNGLIHFDIKPENVMCCSLN-CLNIKIIDFGLTKCARSRTPINRNFGFFS 384
QV + Y+H G++H D+KPEN++ S + I I DFGL+K ++ G
Sbjct: 127 QVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGDVMSTACGTPG 186
Query: 385 SVAPELYSGNVLTTAYDMWSVGILMGIGLLGYTPRIIGKRSRRLSVV------FTSQEYL 438
VAPE+ + + A D WS+G++ I L GY P S+ + F S +
Sbjct: 187 YVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWD 246
Query: 439 CISGAALHFFGKCLHTNPSRRLTAAQALNHPWM 471
IS +A F + +P++R T QA HPW+
Sbjct: 247 DISDSAKDFIRNLMEKDPNKRYTCEQAARHPWI 279
>AL391314-1|CAI14409.1| 357|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 357
Score = 117 bits (282), Expect = 1e-25
Identities = 82/273 (30%), Positives = 135/273 (49%), Gaps = 13/273 (4%)
Query: 211 TSPQYLKSLQNFYRDFLPLKLIGSGVYGKVMLIRSNA-GKQFVAKTVISQY---QTNSME 266
+S + K ++ + F + +G+G + +V+L A GK F K + + + +S+E
Sbjct: 8 SSSSWKKQAEDIKKIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKESSIE 67
Query: 267 -EYSTLRILRNTPNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLR 325
E + LR +++ NIV L + Y + VM+ + GG LFDR +E+D +R
Sbjct: 68 NEIAVLRKIKHE-NIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIR 126
Query: 326 QVCSGLQYIHNNGLIHFDIKPENVMCCSLN-CLNIKIIDFGLTKCARSRTPINRNFGFFS 384
QV + Y+H G++H D+KPEN++ S + I I DFGL+K ++ G
Sbjct: 127 QVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGDVMSTACGTPG 186
Query: 385 SVAPELYSGNVLTTAYDMWSVGILMGIGLLGYTPRIIGKRSRRLSVV------FTSQEYL 438
VAPE+ + + A D WS+G++ I L GY P S+ + F S +
Sbjct: 187 YVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWD 246
Query: 439 CISGAALHFFGKCLHTNPSRRLTAAQALNHPWM 471
IS +A F + +P++R T QA HPW+
Sbjct: 247 DISDSAKDFIRNLMEKDPNKRYTCEQAARHPWI 279
>AJ277892-1|CAD12455.1|26926|Homo sapiens N2B-Titin Isoform protein.
Length = 26926
Score = 117 bits (282), Expect = 1e-25
Identities = 79/264 (29%), Positives = 134/264 (50%), Gaps = 11/264 (4%)
Query: 218 SLQNFYRDFLPLKLIGSGVYGKV-MLIRSNAGKQFVAK--TVISQYQTNSMEEYSTLRIL 274
S + Y ++ + +G G +G V + +++ K ++AK V Q +E S L I
Sbjct: 24746 STKELYEKYMIAEDLGRGEFGIVHRCVETSSKKTYMAKFVKVKGTDQVLVKKEISILNIA 24805
Query: 275 RNTPNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQC-ISERDIKIYLRQVCSGLQY 333
R+ NI+ L E + V + E + G ++F+R ++ER+I Y+ QVC LQ+
Sbjct: 24806 RHR-NILHLHESFESMEELVMIFEFISGLDIFERINTSAFELNEREIVSYVHQVCEALQF 24864
Query: 334 IHNNGLIHFDIKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSG 393
+H++ + HFDI+PEN++ + IKII+FG + + F APE++
Sbjct: 24865 LHSHNIGHFDIRPENIIYQTRRSSTIKIIEFGQARQLKPGDNFRLLFTAPEYYAPEVHQH 24924
Query: 394 NVLTTAYDMWSVGILMGIGLLGYTPRI------IGKRSRRLSVVFTSQEYLCISGAALHF 447
+V++TA DMWS+G L+ + L G P + I + F + + IS A+ F
Sbjct: 24925 DVVSTATDMWSLGTLVYVLLSGINPFLAETNQQIIENIMNAEYTFDEEAFKEISIEAMDF 24984
Query: 448 FGKCLHTNPSRRLTAAQALNHPWM 471
+ L R+TA++AL HPW+
Sbjct: 24985 VDRLLVKERKSRMTASEALQHPWL 25008
>AF286366-1|AAG00534.1| 357|Homo sapiens CamKI-like protein kinase
protein.
Length = 357
Score = 117 bits (282), Expect = 1e-25
Identities = 82/273 (30%), Positives = 135/273 (49%), Gaps = 13/273 (4%)
Query: 211 TSPQYLKSLQNFYRDFLPLKLIGSGVYGKVMLIRSNA-GKQFVAKTVISQY---QTNSME 266
+S + K ++ + F + +G+G + +V+L A GK F K + + + +S+E
Sbjct: 8 SSSSWKKQAEDIKKIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKESSIE 67
Query: 267 -EYSTLRILRNTPNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLR 325
E + LR +++ NIV L + Y + VM+ + GG LFDR +E+D +R
Sbjct: 68 NEIAVLRKIKHE-NIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIR 126
Query: 326 QVCSGLQYIHNNGLIHFDIKPENVMCCSLN-CLNIKIIDFGLTKCARSRTPINRNFGFFS 384
QV + Y+H G++H D+KPEN++ S + I I DFGL+K ++ G
Sbjct: 127 QVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGDVMSTACGTPG 186
Query: 385 SVAPELYSGNVLTTAYDMWSVGILMGIGLLGYTPRIIGKRSRRLSVV------FTSQEYL 438
VAPE+ + + A D WS+G++ I L GY P S+ + F S +
Sbjct: 187 YVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWD 246
Query: 439 CISGAALHFFGKCLHTNPSRRLTAAQALNHPWM 471
IS +A F + +P++R T QA HPW+
Sbjct: 247 DISDSAKDFIRNLMEKDPNKRYTCEQAARHPWI 279
>AB081726-1|BAC19846.1| 385|Homo sapiens CaM-kinase I delta
protein.
Length = 385
Score = 117 bits (282), Expect = 1e-25
Identities = 82/273 (30%), Positives = 135/273 (49%), Gaps = 13/273 (4%)
Query: 211 TSPQYLKSLQNFYRDFLPLKLIGSGVYGKVMLIRSNA-GKQFVAKTVISQY---QTNSME 266
+S + K ++ + F + +G+G + +V+L A GK F K + + + +S+E
Sbjct: 8 SSSSWKKQAEDIKKIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKESSIE 67
Query: 267 -EYSTLRILRNTPNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLR 325
E + LR +++ NIV L + Y + VM+ + GG LFDR +E+D +R
Sbjct: 68 NEIAVLRKIKHE-NIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIR 126
Query: 326 QVCSGLQYIHNNGLIHFDIKPENVMCCSLN-CLNIKIIDFGLTKCARSRTPINRNFGFFS 384
QV + Y+H G++H D+KPEN++ S + I I DFGL+K ++ G
Sbjct: 127 QVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGDVMSTACGTPG 186
Query: 385 SVAPELYSGNVLTTAYDMWSVGILMGIGLLGYTPRIIGKRSRRLSVV------FTSQEYL 438
VAPE+ + + A D WS+G++ I L GY P S+ + F S +
Sbjct: 187 YVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWD 246
Query: 439 CISGAALHFFGKCLHTNPSRRLTAAQALNHPWM 471
IS +A F + +P++R T QA HPW+
Sbjct: 247 DISDSAKDFIRNLMEKDPNKRYTCEQAARHPWI 279
>X76104-1|CAA53712.1| 1431|Homo sapiens DAP-kinase protein.
Length = 1431
Score = 117 bits (281), Expect = 2e-25
Identities = 77/257 (29%), Positives = 123/257 (47%), Gaps = 17/257 (6%)
Query: 232 IGSGVYGKVMLIRSNA-GKQFVAKTVISQYQTNSMEEYSTLRILRNT--------PNIVK 282
+GSG + V R + G Q+ AK + + +S S I R PN++
Sbjct: 19 LGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRRGVSREDIEREVSILKEIQHPNVIT 78
Query: 283 LIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHF 342
L E Y + + + ++E + GG LFD + ++E + +L+Q+ +G+ Y+H+ + HF
Sbjct: 79 LHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATEFLKQILNGVYYLHSLQIAHF 138
Query: 343 DIKPENVMCCSLNC--LNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLTTAY 400
D+KPEN+M N IKIIDFGL FG VAPE+ + L
Sbjct: 139 DLKPENIMLLDRNVPKPRIKIIDFGLAHKIDFGNEFKNIFGTPEFVAPEIVNYEPLGLEA 198
Query: 401 DMWSVGILMGIGLLGYTPRIIGKRSRRLSVV------FTSQEYLCISGAALHFFGKCLHT 454
DMWS+G++ I L G +P + + L+ V F + + S A F + L
Sbjct: 199 DMWSIGVITYILLSGASPFLGDTKQETLANVSAVNYEFEDEYFSNTSALAKDFIRRLLVK 258
Query: 455 NPSRRLTAAQALNHPWM 471
+P +R+T +L HPW+
Sbjct: 259 DPKKRMTIQDSLQHPWI 275
>DQ436495-1|ABD96827.1| 1430|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1430
Score = 117 bits (281), Expect = 2e-25
Identities = 77/257 (29%), Positives = 123/257 (47%), Gaps = 17/257 (6%)
Query: 232 IGSGVYGKVMLIRSNA-GKQFVAKTVISQYQTNSMEEYSTLRILRNT--------PNIVK 282
+GSG + V R + G Q+ AK + + +S S I R PN++
Sbjct: 19 LGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRRGVSREDIEREVSILKEIQHPNVIT 78
Query: 283 LIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHF 342
L E Y + + + ++E + GG LFD + ++E + +L+Q+ +G+ Y+H+ + HF
Sbjct: 79 LHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATEFLKQILNGVYYLHSLQIAHF 138
Query: 343 DIKPENVMCCSLNC--LNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLTTAY 400
D+KPEN+M N IKIIDFGL FG VAPE+ + L
Sbjct: 139 DLKPENIMLLDRNVPKPRIKIIDFGLAHKIDFGNEFKNIFGTPEFVAPEIVNYEPLGLEA 198
Query: 401 DMWSVGILMGIGLLGYTPRIIGKRSRRLSVV------FTSQEYLCISGAALHFFGKCLHT 454
DMWS+G++ I L G +P + + L+ V F + + S A F + L
Sbjct: 199 DMWSIGVITYILLSGASPFLGDTKQETLANVSAVNYEFEDEYFSNTSALAKDFIRRLLVK 258
Query: 455 NPSRRLTAAQALNHPWM 471
+P +R+T +L HPW+
Sbjct: 259 DPKKRMTIQDSLQHPWI 275
>BT006935-1|AAP35581.1| 367|Homo sapiens death-associated protein
kinase 1 protein.
Length = 367
Score = 117 bits (281), Expect = 2e-25
Identities = 77/257 (29%), Positives = 123/257 (47%), Gaps = 17/257 (6%)
Query: 232 IGSGVYGKVMLIRSNA-GKQFVAKTVISQYQTNSMEEYSTLRILRNT--------PNIVK 282
+GSG + V R + G Q+ AK + + +S S I R PN++
Sbjct: 19 LGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRRGVSREDIEREVSILKEIQHPNVIT 78
Query: 283 LIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHF 342
L E Y + + + ++E + GG LFD + ++E + +L+Q+ +G+ Y+H+ + HF
Sbjct: 79 LHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATEFLKQILNGVYYLHSLQIAHF 138
Query: 343 DIKPENVMCCSLNC--LNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLTTAY 400
D+KPEN+M N IKIIDFGL FG VAPE+ + L
Sbjct: 139 DLKPENIMLLDRNVPKPRIKIIDFGLAHKIDFGNEFKNIFGTPEFVAPEIVNYEPLGLEA 198
Query: 401 DMWSVGILMGIGLLGYTPRIIGKRSRRLSVV------FTSQEYLCISGAALHFFGKCLHT 454
DMWS+G++ I L G +P + + L+ V F + + S A F + L
Sbjct: 199 DMWSIGVITYILLSGASPFLGDTKQETLANVSAVNYEFEDEYFSNTSALAKDFIRRLLVK 258
Query: 455 NPSRRLTAAQALNHPWM 471
+P +R+T +L HPW+
Sbjct: 259 DPKKRMTIQDSLQHPWI 275
>BC113660-1|AAI13661.1| 1430|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1430
Score = 117 bits (281), Expect = 2e-25
Identities = 77/257 (29%), Positives = 123/257 (47%), Gaps = 17/257 (6%)
Query: 232 IGSGVYGKVMLIRSNA-GKQFVAKTVISQYQTNSMEEYSTLRILRNT--------PNIVK 282
+GSG + V R + G Q+ AK + + +S S I R PN++
Sbjct: 19 LGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRRGVSREDIEREVSILKEIQHPNVIT 78
Query: 283 LIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHF 342
L E Y + + + ++E + GG LFD + ++E + +L+Q+ +G+ Y+H+ + HF
Sbjct: 79 LHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATEFLKQILNGVYYLHSLQIAHF 138
Query: 343 DIKPENVMCCSLNC--LNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLTTAY 400
D+KPEN+M N IKIIDFGL FG VAPE+ + L
Sbjct: 139 DLKPENIMLLDRNVPKPRIKIIDFGLAHKIDFGNEFKNIFGTPEFVAPEIVNYEPLGLEA 198
Query: 401 DMWSVGILMGIGLLGYTPRIIGKRSRRLSVV------FTSQEYLCISGAALHFFGKCLHT 454
DMWS+G++ I L G +P + + L+ V F + + S A F + L
Sbjct: 199 DMWSIGVITYILLSGASPFLGDTKQETLANVSAVNYEFEDEYFSNTSALAKDFIRRLLVK 258
Query: 455 NPSRRLTAAQALNHPWM 471
+P +R+T +L HPW+
Sbjct: 259 DPKKRMTIQDSLQHPWI 275
>AL591852-1|CAH71696.1| 1455|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1455
Score = 117 bits (281), Expect = 2e-25
Identities = 77/257 (29%), Positives = 123/257 (47%), Gaps = 17/257 (6%)
Query: 232 IGSGVYGKVMLIRSNA-GKQFVAKTVISQYQTNSMEEYSTLRILRNT--------PNIVK 282
+GSG + V R + G Q+ AK + + +S S I R PN++
Sbjct: 19 LGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRRGVSREDIEREVSILKEIQHPNVIT 78
Query: 283 LIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHF 342
L E Y + + + ++E + GG LFD + ++E + +L+Q+ +G+ Y+H+ + HF
Sbjct: 79 LHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATEFLKQILNGVYYLHSLQIAHF 138
Query: 343 DIKPENVMCCSLNC--LNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLTTAY 400
D+KPEN+M N IKIIDFGL FG VAPE+ + L
Sbjct: 139 DLKPENIMLLDRNVPKPRIKIIDFGLAHKIDFGNEFKNIFGTPEFVAPEIVNYEPLGLEA 198
Query: 401 DMWSVGILMGIGLLGYTPRIIGKRSRRLSVV------FTSQEYLCISGAALHFFGKCLHT 454
DMWS+G++ I L G +P + + L+ V F + + S A F + L
Sbjct: 199 DMWSIGVITYILLSGASPFLGDTKQETLANVSAVNYEFEDEYFSNTSALAKDFIRRLLVK 258
Query: 455 NPSRRLTAAQALNHPWM 471
+P +R+T +L HPW+
Sbjct: 259 DPKKRMTIQDSLQHPWI 275
>AL161787-1|CAH73544.1| 1455|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1455
Score = 117 bits (281), Expect = 2e-25
Identities = 77/257 (29%), Positives = 123/257 (47%), Gaps = 17/257 (6%)
Query: 232 IGSGVYGKVMLIRSNA-GKQFVAKTVISQYQTNSMEEYSTLRILRNT--------PNIVK 282
+GSG + V R + G Q+ AK + + +S S I R PN++
Sbjct: 19 LGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRRGVSREDIEREVSILKEIQHPNVIT 78
Query: 283 LIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHF 342
L E Y + + + ++E + GG LFD + ++E + +L+Q+ +G+ Y+H+ + HF
Sbjct: 79 LHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATEFLKQILNGVYYLHSLQIAHF 138
Query: 343 DIKPENVMCCSLNC--LNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLTTAY 400
D+KPEN+M N IKIIDFGL FG VAPE+ + L
Sbjct: 139 DLKPENIMLLDRNVPKPRIKIIDFGLAHKIDFGNEFKNIFGTPEFVAPEIVNYEPLGLEA 198
Query: 401 DMWSVGILMGIGLLGYTPRIIGKRSRRLSVV------FTSQEYLCISGAALHFFGKCLHT 454
DMWS+G++ I L G +P + + L+ V F + + S A F + L
Sbjct: 199 DMWSIGVITYILLSGASPFLGDTKQETLANVSAVNYEFEDEYFSNTSALAKDFIRRLLVK 258
Query: 455 NPSRRLTAAQALNHPWM 471
+P +R+T +L HPW+
Sbjct: 259 DPKKRMTIQDSLQHPWI 275
>AL160279-1|CAI16306.1| 1455|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1455
Score = 117 bits (281), Expect = 2e-25
Identities = 77/257 (29%), Positives = 123/257 (47%), Gaps = 17/257 (6%)
Query: 232 IGSGVYGKVMLIRSNA-GKQFVAKTVISQYQTNSMEEYSTLRILRNT--------PNIVK 282
+GSG + V R + G Q+ AK + + +S S I R PN++
Sbjct: 19 LGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRRGVSREDIEREVSILKEIQHPNVIT 78
Query: 283 LIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHF 342
L E Y + + + ++E + GG LFD + ++E + +L+Q+ +G+ Y+H+ + HF
Sbjct: 79 LHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATEFLKQILNGVYYLHSLQIAHF 138
Query: 343 DIKPENVMCCSLNC--LNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLTTAY 400
D+KPEN+M N IKIIDFGL FG VAPE+ + L
Sbjct: 139 DLKPENIMLLDRNVPKPRIKIIDFGLAHKIDFGNEFKNIFGTPEFVAPEIVNYEPLGLEA 198
Query: 401 DMWSVGILMGIGLLGYTPRIIGKRSRRLSVV------FTSQEYLCISGAALHFFGKCLHT 454
DMWS+G++ I L G +P + + L+ V F + + S A F + L
Sbjct: 199 DMWSIGVITYILLSGASPFLGDTKQETLANVSAVNYEFEDEYFSNTSALAKDFIRRLLVK 258
Query: 455 NPSRRLTAAQALNHPWM 471
+P +R+T +L HPW+
Sbjct: 259 DPKKRMTIQDSLQHPWI 275
>AB208871-1|BAD92108.1| 1433|Homo sapiens Hypothetical protein
DKFZp781I035 variant protein.
Length = 1433
Score = 117 bits (281), Expect = 2e-25
Identities = 77/257 (29%), Positives = 123/257 (47%), Gaps = 17/257 (6%)
Query: 232 IGSGVYGKVMLIRSNA-GKQFVAKTVISQYQTNSMEEYSTLRILRNT--------PNIVK 282
+GSG + V R + G Q+ AK + + +S S I R PN++
Sbjct: 22 LGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRRGVSREDIEREVSILKEIQHPNVIT 81
Query: 283 LIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHF 342
L E Y + + + ++E + GG LFD + ++E + +L+Q+ +G+ Y+H+ + HF
Sbjct: 82 LHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATEFLKQILNGVYYLHSLQIAHF 141
Query: 343 DIKPENVMCCSLNC--LNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLTTAY 400
D+KPEN+M N IKIIDFGL FG VAPE+ + L
Sbjct: 142 DLKPENIMLLDRNVPKPRIKIIDFGLAHKIDFGNEFKNIFGTPEFVAPEIVNYEPLGLEA 201
Query: 401 DMWSVGILMGIGLLGYTPRIIGKRSRRLSVV------FTSQEYLCISGAALHFFGKCLHT 454
DMWS+G++ I L G +P + + L+ V F + + S A F + L
Sbjct: 202 DMWSIGVITYILLSGASPFLGDTKQETLANVSAVNYEFEDEYFSNTSALAKDFIRRLLVK 261
Query: 455 NPSRRLTAAQALNHPWM 471
+P +R+T +L HPW+
Sbjct: 262 DPKKRMTIQDSLQHPWI 278
>BC062616-1|AAH62616.1| 424|Homo sapiens protein serine kinase H1
protein.
Length = 424
Score = 116 bits (278), Expect = 4e-25
Identities = 87/300 (29%), Positives = 141/300 (47%), Gaps = 17/300 (5%)
Query: 231 LIGSGVYGKVMLIRSNAGKQ-FVAKTVISQYQTNSMEEYSTLRILRNT--PNIVKLIECY 287
LIG G + +V+ + A +Q + K + ++Y+ S LR+LR NI++L+E +
Sbjct: 103 LIGRGSFSRVVRVEHRATRQPYAIKMIETKYREGREVCESELRVLRRVRHANIIQLVEVF 162
Query: 288 SDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFDIKPE 347
VME GG LFDR +ERD L+ V G++Y+H G+ H D+KPE
Sbjct: 163 ETQERVYMVMELATGGELFDRIIAKGSFTERDATRVLQMVLDGVRYLHALGITHRDLKPE 222
Query: 348 NVMCCSLNC-LNIKIIDFGLTKCARSRTP--INRNFGFFSSVAPELYSGNVLTTAYDMWS 404
N++ I I DFGL + + G +APE+ T + DMW+
Sbjct: 223 NLLYYHPGTDSKIIITDFGLASARKKGDDCLMKTTCGTPEYIAPEVLVRKPYTNSVDMWA 282
Query: 405 VGILMGIGLLGYTPRIIGKRSR------RLSVVFTSQEYLCISGAALHFFGKCLHTNPSR 458
+G++ I L G P R+R R ++ + + +S A F + L +P
Sbjct: 283 LGVIAYILLSGTMPFEDDNRTRLYRQILRGKYSYSGEPWPSVSNLAKDFIDRLLTVDPGA 342
Query: 459 RLTAAQALNHPWMFDTCPHPLSWKKPSKNRRYNRYMGQRSSYGCDYLKLMETFLLRNSKS 518
R+TA QAL HPW+ S + +R ++ + +R+S C K ++ R+S+S
Sbjct: 343 RMTALQALRHPWVVSMA---ASSSMKNLHRSISQNLLKRASSRCQSTKSAQS--TRSSRS 397
>AJ272212-1|CAB91984.1| 424|Homo sapiens protein serine kinase
protein.
Length = 424
Score = 116 bits (278), Expect = 4e-25
Identities = 87/300 (29%), Positives = 141/300 (47%), Gaps = 17/300 (5%)
Query: 231 LIGSGVYGKVMLIRSNAGKQ-FVAKTVISQYQTNSMEEYSTLRILRNT--PNIVKLIECY 287
LIG G + +V+ + A +Q + K + ++Y+ S LR+LR NI++L+E +
Sbjct: 103 LIGRGSFSRVVRVEHRATRQPYAIKMIETKYREGREVCESELRVLRRVRHANIIQLVEVF 162
Query: 288 SDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFDIKPE 347
VME GG LFDR +ERD L+ V G++Y+H G+ H D+KPE
Sbjct: 163 ETQERVYMVMELATGGELFDRIIAKGSFTERDATRVLQMVLDGVRYLHALGITHRDLKPE 222
Query: 348 NVMCCSLNC-LNIKIIDFGLTKCARSRTP--INRNFGFFSSVAPELYSGNVLTTAYDMWS 404
N++ I I DFGL + + G +APE+ T + DMW+
Sbjct: 223 NLLYYHPGTDSKIIITDFGLASARKKGDDCLMKTTCGTPEYIAPEVLVRKPYTNSVDMWA 282
Query: 405 VGILMGIGLLGYTPRIIGKRSR------RLSVVFTSQEYLCISGAALHFFGKCLHTNPSR 458
+G++ I L G P R+R R ++ + + +S A F + L +P
Sbjct: 283 LGVIAYILLSGTMPFEDDNRTRLYRQILRGKYSYSGEPWPSVSNLAKDFIDRLLTVDPGA 342
Query: 459 RLTAAQALNHPWMFDTCPHPLSWKKPSKNRRYNRYMGQRSSYGCDYLKLMETFLLRNSKS 518
R+TA QAL HPW+ S + +R ++ + +R+S C K ++ R+S+S
Sbjct: 343 RMTALQALRHPWVVSMA---ASSSMKNLHRSISQNLLKRASSRCQSTKSAQS--TRSSRS 397
>L07597-1|AAC82497.1| 735|Homo sapiens ribosomal protein S6 kinase
1 protein.
Length = 735
Score = 115 bits (276), Expect = 7e-25
Identities = 86/284 (30%), Positives = 131/284 (46%), Gaps = 14/284 (4%)
Query: 202 RPYATE-PLITSPQYLKSLQNFYRD-FLPLKLIGSGVYGKVMLIRSNAGKQFVAKTVISQ 259
+P A + PL + Q L + D ++ + IG G Y + A A VI +
Sbjct: 392 KPRAPQAPLHSVVQQLHGKNLVFSDGYVVKETIGVGSYSECKRCVHKATNMEYAVKVIDK 451
Query: 260 YQTNSMEEYSTLRILRNTPNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERD 319
+ + EE L PNI+ L + Y DG + V E + GG L D+ + SER+
Sbjct: 452 SKRDPSEEIEILLRYGQHPNIITLKDVYDDGKHVYLVTELMRGGELLDKILRQKFFSERE 511
Query: 320 IKIYLRQVCSGLQYIHNNGLIHFDIKPENVMCC--SLNCLNIKIIDFGLTKCARSRTPIN 377
L + ++Y+H+ G++H D+KP N++ S N ++I DFG K R+ +
Sbjct: 512 ASFVLHTIGKTVEYLHSQGVVHRDLKPSNILYVDESGNPECLRICDFGFAKQLRAENGLL 571
Query: 378 RNFGFFSS-VAPELYSGNVLTTAYDMWSVGILMGIGLLGYTPRIIGKR-------SRRLS 429
+ ++ VAPE+ D+WS+GIL+ L GYTP G +R S
Sbjct: 572 MTPCYTANFVAPEVLKRQGYDEGCDIWSLGILLYTMLAGYTPFANGPSDTPEEILTRIGS 631
Query: 430 VVFT--SQEYLCISGAALHFFGKCLHTNPSRRLTAAQALNHPWM 471
FT + +S A K LH +P +RLTA Q L HPW+
Sbjct: 632 GKFTLSGGNWNTVSETAKDLVSKMLHVDPHQRLTAKQVLQHPWV 675
Score = 88.6 bits (210), Expect = 7e-17
Identities = 69/244 (28%), Positives = 118/244 (48%), Gaps = 15/244 (6%)
Query: 229 LKLIGSGVYGKVMLIRS----NAGKQFVAK-----TVISQYQTNSMEEYSTLRILRNTPN 279
LK++G G +GKV L+R ++G + K T+ + + + E L + N P
Sbjct: 65 LKVLGQGSFGKVFLVRKVTRPDSGHLYAMKVLKKATLKVRDRVRTKMERDILADV-NHPF 123
Query: 280 IVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGL 339
+VKL + +++ L GG+LF R +E D+K YL ++ GL ++H+ G+
Sbjct: 124 VVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLHSLGI 183
Query: 340 IHFDIKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNF-GFFSSVAPELYSGNVLTT 398
I+ D+KPEN++ +IK+ DFGL+K A +F G +APE+ + +
Sbjct: 184 IYRDLKPENILLDEEG--HIKLTDFGLSKEAIDHEKKAYSFCGTVEYMAPEVVNRQGHSH 241
Query: 399 AYDMWSVGILMGIGLLGYTPRIIGKRSRRLSVVFTSQEYL--CISGAALHFFGKCLHTNP 456
+ D WS G+LM L G P R ++++ ++ + +S A NP
Sbjct: 242 SADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLGMPQFLSTEAQSLLRALFKRNP 301
Query: 457 SRRL 460
+ RL
Sbjct: 302 ANRL 305
>BC014966-1|AAH14966.1| 735|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 1 protein.
Length = 735
Score = 115 bits (276), Expect = 7e-25
Identities = 86/284 (30%), Positives = 131/284 (46%), Gaps = 14/284 (4%)
Query: 202 RPYATE-PLITSPQYLKSLQNFYRD-FLPLKLIGSGVYGKVMLIRSNAGKQFVAKTVISQ 259
+P A + PL + Q L + D ++ + IG G Y + A A VI +
Sbjct: 392 KPRAPQAPLHSVVQQLHGKNLVFSDGYVVKETIGVGSYSECKRCVHKATNMEYAVKVIDK 451
Query: 260 YQTNSMEEYSTLRILRNTPNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERD 319
+ + EE L PNI+ L + Y DG + V E + GG L D+ + SER+
Sbjct: 452 SKRDPSEEIEILLRYGQHPNIITLKDVYDDGKHVYLVTELMRGGELLDKILRQKFFSERE 511
Query: 320 IKIYLRQVCSGLQYIHNNGLIHFDIKPENVMCC--SLNCLNIKIIDFGLTKCARSRTPIN 377
L + ++Y+H+ G++H D+KP N++ S N ++I DFG K R+ +
Sbjct: 512 ASFVLHTIGKTVEYLHSQGVVHRDLKPSNILYVDESGNPECLRICDFGFAKQLRAENGLL 571
Query: 378 RNFGFFSS-VAPELYSGNVLTTAYDMWSVGILMGIGLLGYTPRIIGKR-------SRRLS 429
+ ++ VAPE+ D+WS+GIL+ L GYTP G +R S
Sbjct: 572 MTPCYTANFVAPEVLKRQGYDEGCDIWSLGILLYTMLAGYTPFANGPSDTPEEILTRIGS 631
Query: 430 VVFT--SQEYLCISGAALHFFGKCLHTNPSRRLTAAQALNHPWM 471
FT + +S A K LH +P +RLTA Q L HPW+
Sbjct: 632 GKFTLSGGNWNTVSETAKDLVSKMLHVDPHQRLTAKQVLQHPWV 675
Score = 88.6 bits (210), Expect = 7e-17
Identities = 69/244 (28%), Positives = 118/244 (48%), Gaps = 15/244 (6%)
Query: 229 LKLIGSGVYGKVMLIRS----NAGKQFVAK-----TVISQYQTNSMEEYSTLRILRNTPN 279
LK++G G +GKV L+R ++G + K T+ + + + E L + N P
Sbjct: 65 LKVLGQGSFGKVFLVRKVTRPDSGHLYAMKVLKKATLKVRDRVRTKMERDILADV-NHPF 123
Query: 280 IVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGL 339
+VKL + +++ L GG+LF R +E D+K YL ++ GL ++H+ G+
Sbjct: 124 VVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLHSLGI 183
Query: 340 IHFDIKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNF-GFFSSVAPELYSGNVLTT 398
I+ D+KPEN++ +IK+ DFGL+K A +F G +APE+ + +
Sbjct: 184 IYRDLKPENILLDEEG--HIKLTDFGLSKEAIDHEKKAYSFCGTVEYMAPEVVNRQGHSH 241
Query: 399 AYDMWSVGILMGIGLLGYTPRIIGKRSRRLSVVFTSQEYL--CISGAALHFFGKCLHTNP 456
+ D WS G+LM L G P R ++++ ++ + +S A NP
Sbjct: 242 SADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLGMPQFLSTEAQSLLRALFKRNP 301
Query: 457 SRRL 460
+ RL
Sbjct: 302 ANRL 305
>AL627313-6|CAI14649.1| 735|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 1 protein.
Length = 735
Score = 115 bits (276), Expect = 7e-25
Identities = 86/284 (30%), Positives = 131/284 (46%), Gaps = 14/284 (4%)
Query: 202 RPYATE-PLITSPQYLKSLQNFYRD-FLPLKLIGSGVYGKVMLIRSNAGKQFVAKTVISQ 259
+P A + PL + Q L + D ++ + IG G Y + A A VI +
Sbjct: 392 KPRAPQAPLHSVVQQLHGKNLVFSDGYVVKETIGVGSYSECKRCVHKATNMEYAVKVIDK 451
Query: 260 YQTNSMEEYSTLRILRNTPNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERD 319
+ + EE L PNI+ L + Y DG + V E + GG L D+ + SER+
Sbjct: 452 SKRDPSEEIEILLRYGQHPNIITLKDVYDDGKHVYLVTELMRGGELLDKILRQKFFSERE 511
Query: 320 IKIYLRQVCSGLQYIHNNGLIHFDIKPENVMCC--SLNCLNIKIIDFGLTKCARSRTPIN 377
L + ++Y+H+ G++H D+KP N++ S N ++I DFG K R+ +
Sbjct: 512 ASFVLHTIGKTVEYLHSQGVVHRDLKPSNILYVDESGNPECLRICDFGFAKQLRAENGLL 571
Query: 378 RNFGFFSS-VAPELYSGNVLTTAYDMWSVGILMGIGLLGYTPRIIGKR-------SRRLS 429
+ ++ VAPE+ D+WS+GIL+ L GYTP G +R S
Sbjct: 572 MTPCYTANFVAPEVLKRQGYDEGCDIWSLGILLYTMLAGYTPFANGPSDTPEEILTRIGS 631
Query: 430 VVFT--SQEYLCISGAALHFFGKCLHTNPSRRLTAAQALNHPWM 471
FT + +S A K LH +P +RLTA Q L HPW+
Sbjct: 632 GKFTLSGGNWNTVSETAKDLVSKMLHVDPHQRLTAKQVLQHPWV 675
Score = 88.6 bits (210), Expect = 7e-17
Identities = 69/244 (28%), Positives = 118/244 (48%), Gaps = 15/244 (6%)
Query: 229 LKLIGSGVYGKVMLIRS----NAGKQFVAK-----TVISQYQTNSMEEYSTLRILRNTPN 279
LK++G G +GKV L+R ++G + K T+ + + + E L + N P
Sbjct: 65 LKVLGQGSFGKVFLVRKVTRPDSGHLYAMKVLKKATLKVRDRVRTKMERDILADV-NHPF 123
Query: 280 IVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGL 339
+VKL + +++ L GG+LF R +E D+K YL ++ GL ++H+ G+
Sbjct: 124 VVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLHSLGI 183
Query: 340 IHFDIKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNF-GFFSSVAPELYSGNVLTT 398
I+ D+KPEN++ +IK+ DFGL+K A +F G +APE+ + +
Sbjct: 184 IYRDLKPENILLDEEG--HIKLTDFGLSKEAIDHEKKAYSFCGTVEYMAPEVVNRQGHSH 241
Query: 399 AYDMWSVGILMGIGLLGYTPRIIGKRSRRLSVVFTSQEYL--CISGAALHFFGKCLHTNP 456
+ D WS G+LM L G P R ++++ ++ + +S A NP
Sbjct: 242 SADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLGMPQFLSTEAQSLLRALFKRNP 301
Query: 457 SRRL 460
+ RL
Sbjct: 302 ANRL 305
>AL627313-4|CAI14647.1| 578|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 1 protein.
Length = 578
Score = 115 bits (276), Expect = 7e-25
Identities = 86/284 (30%), Positives = 131/284 (46%), Gaps = 14/284 (4%)
Query: 202 RPYATE-PLITSPQYLKSLQNFYRD-FLPLKLIGSGVYGKVMLIRSNAGKQFVAKTVISQ 259
+P A + PL + Q L + D ++ + IG G Y + A A VI +
Sbjct: 235 KPRAPQAPLHSVVQQLHGKNLVFSDGYVVKETIGVGSYSECKRCVHKATNMEYAVKVIDK 294
Query: 260 YQTNSMEEYSTLRILRNTPNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERD 319
+ + EE L PNI+ L + Y DG + V E + GG L D+ + SER+
Sbjct: 295 SKRDPSEEIEILLRYGQHPNIITLKDVYDDGKHVYLVTELMRGGELLDKILRQKFFSERE 354
Query: 320 IKIYLRQVCSGLQYIHNNGLIHFDIKPENVMCC--SLNCLNIKIIDFGLTKCARSRTPIN 377
L + ++Y+H+ G++H D+KP N++ S N ++I DFG K R+ +
Sbjct: 355 ASFVLHTIGKTVEYLHSQGVVHRDLKPSNILYVDESGNPECLRICDFGFAKQLRAENGLL 414
Query: 378 RNFGFFSS-VAPELYSGNVLTTAYDMWSVGILMGIGLLGYTPRIIGKR-------SRRLS 429
+ ++ VAPE+ D+WS+GIL+ L GYTP G +R S
Sbjct: 415 MTPCYTANFVAPEVLKRQGYDEGCDIWSLGILLYTMLAGYTPFANGPSDTPEEILTRIGS 474
Query: 430 VVFT--SQEYLCISGAALHFFGKCLHTNPSRRLTAAQALNHPWM 471
FT + +S A K LH +P +RLTA Q L HPW+
Sbjct: 475 GKFTLSGGNWNTVSETAKDLVSKMLHVDPHQRLTAKQVLQHPWV 518
Score = 65.3 bits (152), Expect = 7e-10
Identities = 44/148 (29%), Positives = 75/148 (50%), Gaps = 5/148 (3%)
Query: 316 SERDIKIYLRQVCSGLQYIHNNGLIHFDIKPENVMCCSLNCLNIKIIDFGLTKCARSRTP 375
+E D+K YL ++ GL ++H+ G+I+ D+KPEN++ +IK+ DFGL+K A
Sbjct: 3 TEEDVKFYLAELALGLDHLHSLGIIYRDLKPENILLDEEG--HIKLTDFGLSKEAIDHEK 60
Query: 376 INRNF-GFFSSVAPELYSGNVLTTAYDMWSVGILMGIGLLGYTPRIIGKRSRRLSVVFTS 434
+F G +APE+ + + + D WS G+LM L G P R ++++ +
Sbjct: 61 KAYSFCGTVEYMAPEVVNRQGHSHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKA 120
Query: 435 QEYL--CISGAALHFFGKCLHTNPSRRL 460
+ + +S A NP+ RL
Sbjct: 121 KLGMPQFLSTEAQSLLRALFKRNPANRL 148
>BC127622-1|AAI27623.1| 596|Homo sapiens myosin light chain kinase
2, skeletal muscle protein.
Length = 596
Score = 114 bits (275), Expect = 9e-25
Identities = 68/250 (27%), Positives = 121/250 (48%), Gaps = 10/250 (4%)
Query: 232 IGSGVYGKVMLIRSNA-GKQFVAKTVISQYQTNSMEEYSTLRILR--NTPNIVKLIECYS 288
+G G +G V A G + AK + Q + + ++ N N+++L
Sbjct: 291 LGGGKFGAVCTCMEKATGLKLAAKVIKKQTPKDKEMVLLEIEVMNQLNHRNLIQLYAAIE 350
Query: 289 DGLNWVFVMENLWGGNLFDRFKHHQC-ISERDIKIYLRQVCSGLQYIHNNGLIHFDIKPE 347
V ME + GG LF+R ++E D +++RQ+C G+ ++H ++H D+KPE
Sbjct: 351 TPHEIVLFMEYIEGGELFERIVDEDYHLTEVDTMVFVRQICDGILFMHKMRVLHLDLKPE 410
Query: 348 NVMCCSLNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLTTAYDMWSVGI 407
N++C + +KIIDFGL + + NFG ++PE+ + + ++ DMWS+G+
Sbjct: 411 NILCVNTTGHLVKIIDFGLARRYNPNEKLKVNFGTPEFLSPEVVNYDQISDKTDMWSMGV 470
Query: 408 LMGIGLLGYTPRIIGKRSRRLSVV------FTSQEYLCISGAALHFFGKCLHTNPSRRLT 461
+ + L G +P + + L+ V F + + +S A F + + R+
Sbjct: 471 ITYMLLSGLSPFLGDDDTETLNNVLSGNWYFDEETFEAVSDEAKDFVSNLIVKDQRARMN 530
Query: 462 AAQALNHPWM 471
AAQ L HPW+
Sbjct: 531 AAQCLAHPWL 540
>BC092413-1|AAH92413.1| 596|Homo sapiens myosin light chain kinase
2, skeletal muscle protein.
Length = 596
Score = 114 bits (275), Expect = 9e-25
Identities = 68/250 (27%), Positives = 121/250 (48%), Gaps = 10/250 (4%)
Query: 232 IGSGVYGKVMLIRSNA-GKQFVAKTVISQYQTNSMEEYSTLRILR--NTPNIVKLIECYS 288
+G G +G V A G + AK + Q + + ++ N N+++L
Sbjct: 291 LGGGKFGAVCTCMEKATGLKLAAKVIKKQTPKDKEMVLLEIEVMNQLNHRNLIQLYAAIE 350
Query: 289 DGLNWVFVMENLWGGNLFDRFKHHQC-ISERDIKIYLRQVCSGLQYIHNNGLIHFDIKPE 347
V ME + GG LF+R ++E D +++RQ+C G+ ++H ++H D+KPE
Sbjct: 351 TPHEIVLFMEYIEGGELFERIVDEDYHLTEVDTMVFVRQICDGILFMHKMRVLHLDLKPE 410
Query: 348 NVMCCSLNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLTTAYDMWSVGI 407
N++C + +KIIDFGL + + NFG ++PE+ + + ++ DMWS+G+
Sbjct: 411 NILCVNTTGHLVKIIDFGLARRYNPNEKLKVNFGTPEFLSPEVVNYDQISDKTDMWSMGV 470
Query: 408 LMGIGLLGYTPRIIGKRSRRLSVV------FTSQEYLCISGAALHFFGKCLHTNPSRRLT 461
+ + L G +P + + L+ V F + + +S A F + + R+
Sbjct: 471 ITYMLLSGLSPFLGDDDTETLNNVLSGNWYFDEETFEAVSDEAKDFVSNLIVKDQRARMN 530
Query: 462 AAQALNHPWM 471
AAQ L HPW+
Sbjct: 531 AAQCLAHPWL 540
>BC069627-1|AAH69627.1| 596|Homo sapiens skeletal myosin light
chain kinase protein.
Length = 596
Score = 114 bits (275), Expect = 9e-25
Identities = 68/250 (27%), Positives = 121/250 (48%), Gaps = 10/250 (4%)
Query: 232 IGSGVYGKVMLIRSNA-GKQFVAKTVISQYQTNSMEEYSTLRILR--NTPNIVKLIECYS 288
+G G +G V A G + AK + Q + + ++ N N+++L
Sbjct: 291 LGGGKFGAVCTCMEKATGLKLAAKVIKKQTPKDKEMVLLEIEVMNQLNHRNLIQLYAAIE 350
Query: 289 DGLNWVFVMENLWGGNLFDRFKHHQC-ISERDIKIYLRQVCSGLQYIHNNGLIHFDIKPE 347
V ME + GG LF+R ++E D +++RQ+C G+ ++H ++H D+KPE
Sbjct: 351 TPHEIVLFMEYIEGGELFERIVDEDYHLTEVDTMVFVRQICDGILFMHKMRVLHLDLKPE 410
Query: 348 NVMCCSLNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLTTAYDMWSVGI 407
N++C + +KIIDFGL + + NFG ++PE+ + + ++ DMWS+G+
Sbjct: 411 NILCVNTTGHLVKIIDFGLARRYNPNEKLKVNFGTPEFLSPEVVNYDQISDKTDMWSMGV 470
Query: 408 LMGIGLLGYTPRIIGKRSRRLSVV------FTSQEYLCISGAALHFFGKCLHTNPSRRLT 461
+ + L G +P + + L+ V F + + +S A F + + R+
Sbjct: 471 ITYMLLSGLSPFLGDDDTETLNNVLSGNWYFDEETFEAVSDEAKDFVSNLIVKDQRARMN 530
Query: 462 AAQALNHPWM 471
AAQ L HPW+
Sbjct: 531 AAQCLAHPWL 540
>AL160175-10|CAC10006.1| 596|Homo sapiens myosin light chain kinase
2, skeletal muscle protein.
Length = 596
Score = 114 bits (275), Expect = 9e-25
Identities = 68/250 (27%), Positives = 121/250 (48%), Gaps = 10/250 (4%)
Query: 232 IGSGVYGKVMLIRSNA-GKQFVAKTVISQYQTNSMEEYSTLRILR--NTPNIVKLIECYS 288
+G G +G V A G + AK + Q + + ++ N N+++L
Sbjct: 291 LGGGKFGAVCTCMEKATGLKLAAKVIKKQTPKDKEMVLLEIEVMNQLNHRNLIQLYAAIE 350
Query: 289 DGLNWVFVMENLWGGNLFDRFKHHQC-ISERDIKIYLRQVCSGLQYIHNNGLIHFDIKPE 347
V ME + GG LF+R ++E D +++RQ+C G+ ++H ++H D+KPE
Sbjct: 351 TPHEIVLFMEYIEGGELFERIVDEDYHLTEVDTMVFVRQICDGILFMHKMRVLHLDLKPE 410
Query: 348 NVMCCSLNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLTTAYDMWSVGI 407
N++C + +KIIDFGL + + NFG ++PE+ + + ++ DMWS+G+
Sbjct: 411 NILCVNTTGHLVKIIDFGLARRYNPNEKLKVNFGTPEFLSPEVVNYDQISDKTDMWSMGV 470
Query: 408 LMGIGLLGYTPRIIGKRSRRLSVV------FTSQEYLCISGAALHFFGKCLHTNPSRRLT 461
+ + L G +P + + L+ V F + + +S A F + + R+
Sbjct: 471 ITYMLLSGLSPFLGDDDTETLNNVLSGNWYFDEETFEAVSDEAKDFVSNLIVKDQRARMN 530
Query: 462 AAQALNHPWM 471
AAQ L HPW+
Sbjct: 531 AAQCLAHPWL 540
>AJ272502-1|CAC81354.1| 596|Homo sapiens skeletal muscle-specific
myosin light chain kinase protein.
Length = 596
Score = 114 bits (275), Expect = 9e-25
Identities = 68/250 (27%), Positives = 121/250 (48%), Gaps = 10/250 (4%)
Query: 232 IGSGVYGKVMLIRSNA-GKQFVAKTVISQYQTNSMEEYSTLRILR--NTPNIVKLIECYS 288
+G G +G V A G + AK + Q + + ++ N N+++L
Sbjct: 291 LGGGKFGAVCTCMEKATGLKLAAKVIKKQTPKDKEMVLLEIEVMNQLNHRNLIQLYAAIE 350
Query: 289 DGLNWVFVMENLWGGNLFDRFKHHQC-ISERDIKIYLRQVCSGLQYIHNNGLIHFDIKPE 347
V ME + GG LF+R ++E D +++RQ+C G+ ++H ++H D+KPE
Sbjct: 351 TPHEIVLFMEYIEGGELFERIVDEDYHLTEVDTMVFVRQICDGILFMHKMRVLHLDLKPE 410
Query: 348 NVMCCSLNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLTTAYDMWSVGI 407
N++C + +KIIDFGL + + NFG ++PE+ + + ++ DMWS+G+
Sbjct: 411 NILCVNTTGHLVKIIDFGLARRYNPNEKLKVNFGTPEFLSPEVVNYDQISDKTDMWSMGV 470
Query: 408 LMGIGLLGYTPRIIGKRSRRLSVV------FTSQEYLCISGAALHFFGKCLHTNPSRRLT 461
+ + L G +P + + L+ V F + + +S A F + + R+
Sbjct: 471 ITYMLLSGLSPFLGDDDTETLNNVLSGNWYFDEETFEAVSDEAKDFVSNLIVKDQRARMN 530
Query: 462 AAQALNHPWM 471
AAQ L HPW+
Sbjct: 531 AAQCLAHPWL 540
>AF325549-1|AAK15494.1| 596|Homo sapiens skeletal myosin light
chain kinase protein.
Length = 596
Score = 114 bits (275), Expect = 9e-25
Identities = 68/250 (27%), Positives = 121/250 (48%), Gaps = 10/250 (4%)
Query: 232 IGSGVYGKVMLIRSNA-GKQFVAKTVISQYQTNSMEEYSTLRILR--NTPNIVKLIECYS 288
+G G +G V A G + AK + Q + + ++ N N+++L
Sbjct: 291 LGGGKFGAVCTCMEKATGLKLAAKVIKKQTPKDKEMVLLEIEVMNQLNHRNLIQLYAAIE 350
Query: 289 DGLNWVFVMENLWGGNLFDRFKHHQC-ISERDIKIYLRQVCSGLQYIHNNGLIHFDIKPE 347
V ME + GG LF+R ++E D +++RQ+C G+ ++H ++H D+KPE
Sbjct: 351 TPHEIVLFMEYIEGGELFERIVDEDYHLTEVDTMVFVRQICDGILFMHKMRVLHLDLKPE 410
Query: 348 NVMCCSLNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLTTAYDMWSVGI 407
N++C + +KIIDFGL + + NFG ++PE+ + + ++ DMWS+G+
Sbjct: 411 NILCVNTTGHLVKIIDFGLARRYNPNEKLKVNFGTPEFLSPEVVNYDQISDKTDMWSMGV 470
Query: 408 LMGIGLLGYTPRIIGKRSRRLSVV------FTSQEYLCISGAALHFFGKCLHTNPSRRLT 461
+ + L G +P + + L+ V F + + +S A F + + R+
Sbjct: 471 ITYMLLSGLSPFLGDDDTETLNNVLSGNWYFDEETFEAVSDEAKDFVSNLIVKDQRARMN 530
Query: 462 AAQALNHPWM 471
AAQ L HPW+
Sbjct: 531 AAQCLAHPWL 540
>BC114506-1|AAI14507.1| 370|Homo sapiens death-associated protein
kinase 2 protein.
Length = 370
Score = 113 bits (272), Expect = 2e-24
Identities = 80/278 (28%), Positives = 126/278 (45%), Gaps = 18/278 (6%)
Query: 212 SPQYLKSLQNFYRDFLPL-KLIGSGVYGKVMLIRSNA-GKQFVAKTVISQYQTNSMEEYS 269
SP Q DF + + +GSG + V R + G ++ AK + + S S
Sbjct: 8 SPNMEPFKQQKVEDFYDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGVS 67
Query: 270 TLRILRNTP--------NIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIK 321
I R N++ L + Y + + V ++E + GG LFD + +SE +
Sbjct: 68 REEIEREVSILRQVLHHNVITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEEEAT 127
Query: 322 IYLRQVCSGLQYIHNNGLIHFDIKPENVMCCSLN--CLNIKIIDFGLTKCARSRTPINRN 379
+++Q+ G+ Y+H + HFD+KPEN+M N +IK+IDFGL
Sbjct: 128 SFIKQILDGVNYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIEDGVEFKNI 187
Query: 380 FGFFSSVAPELYSGNVLTTAYDMWSVGILMGIGLLGYTPRIIGKRSRRLSVV------FT 433
FG VAPE+ + L DMWS+G++ I L G +P + + L+ + F
Sbjct: 188 FGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANITAVSYDFD 247
Query: 434 SQEYLCISGAALHFFGKCLHTNPSRRLTAAQALNHPWM 471
+ + S A F K L +RLT +AL HPW+
Sbjct: 248 EEFFSQTSELAKDFIRKLLVKETRKRLTIQEALRHPWI 285
>AF052941-1|AAC35001.1| 370|Homo sapiens DAP-kinase related protein
1 protein.
Length = 370
Score = 113 bits (272), Expect = 2e-24
Identities = 80/278 (28%), Positives = 126/278 (45%), Gaps = 18/278 (6%)
Query: 212 SPQYLKSLQNFYRDFLPL-KLIGSGVYGKVMLIRSNA-GKQFVAKTVISQYQTNSMEEYS 269
SP Q DF + + +GSG + V R + G ++ AK + + S S
Sbjct: 8 SPNMEPFKQQKVEDFYDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGVS 67
Query: 270 TLRILRNTP--------NIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIK 321
I R N++ L + Y + + V ++E + GG LFD + +SE +
Sbjct: 68 REEIEREVSILRQVLHHNVITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEEEAT 127
Query: 322 IYLRQVCSGLQYIHNNGLIHFDIKPENVMCCSLN--CLNIKIIDFGLTKCARSRTPINRN 379
+++Q+ G+ Y+H + HFD+KPEN+M N +IK+IDFGL
Sbjct: 128 SFIKQILDGVNYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIEDGVEFKNI 187
Query: 380 FGFFSSVAPELYSGNVLTTAYDMWSVGILMGIGLLGYTPRIIGKRSRRLSVV------FT 433
FG VAPE+ + L DMWS+G++ I L G +P + + L+ + F
Sbjct: 188 FGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANITSVSYDFD 247
Query: 434 SQEYLCISGAALHFFGKCLHTNPSRRLTAAQALNHPWM 471
+ + S A F K L +RLT +AL HPW+
Sbjct: 248 EEFFSHTSELAKDFIRKLLVKETRKRLTIQEALRHPWI 285
>AB018001-1|BAA88063.1| 370|Homo sapiens Death-associated protein
kinase 2 protein.
Length = 370
Score = 113 bits (272), Expect = 2e-24
Identities = 80/278 (28%), Positives = 126/278 (45%), Gaps = 18/278 (6%)
Query: 212 SPQYLKSLQNFYRDFLPL-KLIGSGVYGKVMLIRSNA-GKQFVAKTVISQYQTNSMEEYS 269
SP Q DF + + +GSG + V R + G ++ AK + + S S
Sbjct: 8 SPNMEPFKQQKVEDFYDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGVS 67
Query: 270 TLRILRNTP--------NIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIK 321
I R N++ L + Y + + V ++E + GG LFD + +SE +
Sbjct: 68 REEIEREVSILRQVLHHNVITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEEEAT 127
Query: 322 IYLRQVCSGLQYIHNNGLIHFDIKPENVMCCSLN--CLNIKIIDFGLTKCARSRTPINRN 379
+++Q+ G+ Y+H + HFD+KPEN+M N +IK+IDFGL
Sbjct: 128 SFIKQILDGVNYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIEDGVEFKNI 187
Query: 380 FGFFSSVAPELYSGNVLTTAYDMWSVGILMGIGLLGYTPRIIGKRSRRLSVV------FT 433
FG VAPE+ + L DMWS+G++ I L G +P + + L+ + F
Sbjct: 188 FGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANITAVSYDFD 247
Query: 434 SQEYLCISGAALHFFGKCLHTNPSRRLTAAQALNHPWM 471
+ + S A F K L +RLT +AL HPW+
Sbjct: 248 EEFFSQTSELAKDFIRKLLVKETRKRLTIQEALRHPWI 285
>CR456418-1|CAG30304.1| 586|Homo sapiens CHEK2 protein.
Length = 586
Score = 112 bits (269), Expect = 5e-24
Identities = 93/283 (32%), Positives = 143/283 (50%), Gaps = 30/283 (10%)
Query: 215 YLKSLQNFYRDFLPLKLIGSGVYGKVMLIRSNAGKQFVAKTVISQ--YQTNSMEEY---- 268
Y K+L++ +++ K +GSG G+V L + VA +IS+ + S E
Sbjct: 255 YPKALRD---EYIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREADPAL 311
Query: 269 ---STLRILR--NTPNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIY 323
+ + IL+ N P I+K I+ + D ++ V+E + GG LFD+ ++ + E K+Y
Sbjct: 312 NVETEIEILKKLNHPCIIK-IKNFFDAEDYYIVLELMEGGELFDKVVGNKRLKEATCKLY 370
Query: 324 LRQVCSGLQYIHNNGLIHFDIKPENVMCCSL--NCLNIKIIDFGLTKCARSRTPINRNFG 381
Q+ +QY+H NG+IH D+KPENV+ S +CL IKI DFG +K + + G
Sbjct: 371 FYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCL-IKITDFGHSKILGETSLMRTLCG 429
Query: 382 FFSSVAPELYSGNVLTTAY----DMWSVGILMGIGLLGYTPRIIGKRSRRLSVVFTSQEY 437
+ +APE+ +V T Y D WS+G+++ I L GY P + L TS +Y
Sbjct: 430 TPTYLAPEVLV-SVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKY 488
Query: 438 LCI-------SGAALHFFGKCLHTNPSRRLTAAQALNHPWMFD 473
I S AL K L +P R T +AL HPW+ D
Sbjct: 489 NFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQD 531
>BC004207-1|AAH04207.1| 543|Homo sapiens CHK2 checkpoint homolog
(S. pombe) protein.
Length = 543
Score = 112 bits (269), Expect = 5e-24
Identities = 93/283 (32%), Positives = 143/283 (50%), Gaps = 30/283 (10%)
Query: 215 YLKSLQNFYRDFLPLKLIGSGVYGKVMLIRSNAGKQFVAKTVISQ--YQTNSMEEY---- 268
Y K+L++ +++ K +GSG G+V L + VA +IS+ + S E
Sbjct: 212 YPKALRD---EYIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREADPAL 268
Query: 269 ---STLRILR--NTPNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIY 323
+ + IL+ N P I+K I+ + D ++ V+E + GG LFD+ ++ + E K+Y
Sbjct: 269 NVETEIEILKKLNHPCIIK-IKNFFDAEDYYIVLELMEGGELFDKVVGNKRLKEATCKLY 327
Query: 324 LRQVCSGLQYIHNNGLIHFDIKPENVMCCSL--NCLNIKIIDFGLTKCARSRTPINRNFG 381
Q+ +QY+H NG+IH D+KPENV+ S +CL IKI DFG +K + + G
Sbjct: 328 FYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCL-IKITDFGHSKILGETSLMRTLCG 386
Query: 382 FFSSVAPELYSGNVLTTAY----DMWSVGILMGIGLLGYTPRIIGKRSRRLSVVFTSQEY 437
+ +APE+ +V T Y D WS+G+++ I L GY P + L TS +Y
Sbjct: 387 TPTYLAPEVLV-SVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKY 445
Query: 438 LCI-------SGAALHFFGKCLHTNPSRRLTAAQALNHPWMFD 473
I S AL K L +P R T +AL HPW+ D
Sbjct: 446 NFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQD 488
>AY800241-1|AAV41895.1| 543|Homo sapiens CHK2 checkpoint homolog
(S. pombe) protein.
Length = 543
Score = 112 bits (269), Expect = 5e-24
Identities = 93/283 (32%), Positives = 143/283 (50%), Gaps = 30/283 (10%)
Query: 215 YLKSLQNFYRDFLPLKLIGSGVYGKVMLIRSNAGKQFVAKTVISQ--YQTNSMEEY---- 268
Y K+L++ +++ K +GSG G+V L + VA +IS+ + S E
Sbjct: 212 YPKALRD---EYIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREADPAL 268
Query: 269 ---STLRILR--NTPNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIY 323
+ + IL+ N P I+K I+ + D ++ V+E + GG LFD+ ++ + E K+Y
Sbjct: 269 NVETEIEILKKLNHPCIIK-IKNFFDAEDYYIVLELMEGGELFDKVVGNKRLKEATCKLY 327
Query: 324 LRQVCSGLQYIHNNGLIHFDIKPENVMCCSL--NCLNIKIIDFGLTKCARSRTPINRNFG 381
Q+ +QY+H NG+IH D+KPENV+ S +CL IKI DFG +K + + G
Sbjct: 328 FYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCL-IKITDFGHSKILGETSLMRTLCG 386
Query: 382 FFSSVAPELYSGNVLTTAY----DMWSVGILMGIGLLGYTPRIIGKRSRRLSVVFTSQEY 437
+ +APE+ +V T Y D WS+G+++ I L GY P + L TS +Y
Sbjct: 387 TPTYLAPEVLV-SVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKY 445
Query: 438 LCI-------SGAALHFFGKCLHTNPSRRLTAAQALNHPWMFD 473
I S AL K L +P R T +AL HPW+ D
Sbjct: 446 NFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQD 488
>AY551303-1|AAS58464.1| 452|Homo sapiens protein kinase Chk2
transcript variant del2-3 protein.
Length = 452
Score = 112 bits (269), Expect = 5e-24
Identities = 93/283 (32%), Positives = 143/283 (50%), Gaps = 30/283 (10%)
Query: 215 YLKSLQNFYRDFLPLKLIGSGVYGKVMLIRSNAGKQFVAKTVISQ--YQTNSMEEY---- 268
Y K+L++ +++ K +GSG G+V L + VA +IS+ + S E
Sbjct: 121 YPKALRD---EYIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREADPAL 177
Query: 269 ---STLRILR--NTPNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIY 323
+ + IL+ N P I+K I+ + D ++ V+E + GG LFD+ ++ + E K+Y
Sbjct: 178 NVETEIEILKKLNHPCIIK-IKNFFDAEDYYIVLELMEGGELFDKVVGNKRLKEATCKLY 236
Query: 324 LRQVCSGLQYIHNNGLIHFDIKPENVMCCSL--NCLNIKIIDFGLTKCARSRTPINRNFG 381
Q+ +QY+H NG+IH D+KPENV+ S +CL IKI DFG +K + + G
Sbjct: 237 FYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCL-IKITDFGHSKILGETSLMRTLCG 295
Query: 382 FFSSVAPELYSGNVLTTAY----DMWSVGILMGIGLLGYTPRIIGKRSRRLSVVFTSQEY 437
+ +APE+ +V T Y D WS+G+++ I L GY P + L TS +Y
Sbjct: 296 TPTYLAPEVLV-SVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKY 354
Query: 438 LCI-------SGAALHFFGKCLHTNPSRRLTAAQALNHPWMFD 473
I S AL K L +P R T +AL HPW+ D
Sbjct: 355 NFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQD 397
>AY551297-1|AAS58458.1| 586|Homo sapiens protein kinase Chk2
transcript variant insX protein.
Length = 586
Score = 112 bits (269), Expect = 5e-24
Identities = 93/283 (32%), Positives = 143/283 (50%), Gaps = 30/283 (10%)
Query: 215 YLKSLQNFYRDFLPLKLIGSGVYGKVMLIRSNAGKQFVAKTVISQ--YQTNSMEEY---- 268
Y K+L++ +++ K +GSG G+V L + VA +IS+ + S E
Sbjct: 255 YPKALRD---EYIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREADPAL 311
Query: 269 ---STLRILR--NTPNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIY 323
+ + IL+ N P I+K I+ + D ++ V+E + GG LFD+ ++ + E K+Y
Sbjct: 312 NVETEIEILKKLNHPCIIK-IKNFFDAEDYYIVLELMEGGELFDKVVGNKRLKEATCKLY 370
Query: 324 LRQVCSGLQYIHNNGLIHFDIKPENVMCCSL--NCLNIKIIDFGLTKCARSRTPINRNFG 381
Q+ +QY+H NG+IH D+KPENV+ S +CL IKI DFG +K + + G
Sbjct: 371 FYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCL-IKITDFGHSKILGETSLMRTLCG 429
Query: 382 FFSSVAPELYSGNVLTTAY----DMWSVGILMGIGLLGYTPRIIGKRSRRLSVVFTSQEY 437
+ +APE+ +V T Y D WS+G+++ I L GY P + L TS +Y
Sbjct: 430 TPTYLAPEVLV-SVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKY 488
Query: 438 LCI-------SGAALHFFGKCLHTNPSRRLTAAQALNHPWMFD 473
I S AL K L +P R T +AL HPW+ D
Sbjct: 489 NFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQD 531
>AL121825-1|CAH73823.1| 543|Homo sapiens CHK2 checkpoint homolog
(S. pombe) protein.
Length = 543
Score = 112 bits (269), Expect = 5e-24
Identities = 93/283 (32%), Positives = 143/283 (50%), Gaps = 30/283 (10%)
Query: 215 YLKSLQNFYRDFLPLKLIGSGVYGKVMLIRSNAGKQFVAKTVISQ--YQTNSMEEY---- 268
Y K+L++ +++ K +GSG G+V L + VA +IS+ + S E
Sbjct: 212 YPKALRD---EYIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREADPAL 268
Query: 269 ---STLRILR--NTPNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIY 323
+ + IL+ N P I+K I+ + D ++ V+E + GG LFD+ ++ + E K+Y
Sbjct: 269 NVETEIEILKKLNHPCIIK-IKNFFDAEDYYIVLELMEGGELFDKVVGNKRLKEATCKLY 327
Query: 324 LRQVCSGLQYIHNNGLIHFDIKPENVMCCSL--NCLNIKIIDFGLTKCARSRTPINRNFG 381
Q+ +QY+H NG+IH D+KPENV+ S +CL IKI DFG +K + + G
Sbjct: 328 FYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCL-IKITDFGHSKILGETSLMRTLCG 386
Query: 382 FFSSVAPELYSGNVLTTAY----DMWSVGILMGIGLLGYTPRIIGKRSRRLSVVFTSQEY 437
+ +APE+ +V T Y D WS+G+++ I L GY P + L TS +Y
Sbjct: 387 TPTYLAPEVLV-SVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKY 445
Query: 438 LCI-------SGAALHFFGKCLHTNPSRRLTAAQALNHPWMFD 473
I S AL K L +P R T +AL HPW+ D
Sbjct: 446 NFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQD 488
>AL117330-1|CAH73875.1| 543|Homo sapiens CHK2 checkpoint homolog
(S. pombe) protein.
Length = 543
Score = 112 bits (269), Expect = 5e-24
Identities = 93/283 (32%), Positives = 143/283 (50%), Gaps = 30/283 (10%)
Query: 215 YLKSLQNFYRDFLPLKLIGSGVYGKVMLIRSNAGKQFVAKTVISQ--YQTNSMEEY---- 268
Y K+L++ +++ K +GSG G+V L + VA +IS+ + S E
Sbjct: 212 YPKALRD---EYIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREADPAL 268
Query: 269 ---STLRILR--NTPNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIY 323
+ + IL+ N P I+K I+ + D ++ V+E + GG LFD+ ++ + E K+Y
Sbjct: 269 NVETEIEILKKLNHPCIIK-IKNFFDAEDYYIVLELMEGGELFDKVVGNKRLKEATCKLY 327
Query: 324 LRQVCSGLQYIHNNGLIHFDIKPENVMCCSL--NCLNIKIIDFGLTKCARSRTPINRNFG 381
Q+ +QY+H NG+IH D+KPENV+ S +CL IKI DFG +K + + G
Sbjct: 328 FYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCL-IKITDFGHSKILGETSLMRTLCG 386
Query: 382 FFSSVAPELYSGNVLTTAY----DMWSVGILMGIGLLGYTPRIIGKRSRRLSVVFTSQEY 437
+ +APE+ +V T Y D WS+G+++ I L GY P + L TS +Y
Sbjct: 387 TPTYLAPEVLV-SVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKY 445
Query: 438 LCI-------SGAALHFFGKCLHTNPSRRLTAAQALNHPWMFD 473
I S AL K L +P R T +AL HPW+ D
Sbjct: 446 NFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQD 488
>AJ131197-1|CAA10319.1| 543|Homo sapiens protein kinase protein.
Length = 543
Score = 112 bits (269), Expect = 5e-24
Identities = 93/283 (32%), Positives = 143/283 (50%), Gaps = 30/283 (10%)
Query: 215 YLKSLQNFYRDFLPLKLIGSGVYGKVMLIRSNAGKQFVAKTVISQ--YQTNSMEEY---- 268
Y K+L++ +++ K +GSG G+V L + VA +IS+ + S E
Sbjct: 212 YPKALRD---EYIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREADPAL 268
Query: 269 ---STLRILR--NTPNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIY 323
+ + IL+ N P I+K I+ + D ++ V+E + GG LFD+ ++ + E K+Y
Sbjct: 269 NVETEIEILKKLNHPCIIK-IKNFFDAEDYYIVLELMEGGELFDKVVGNKRLKEATCKLY 327
Query: 324 LRQVCSGLQYIHNNGLIHFDIKPENVMCCSL--NCLNIKIIDFGLTKCARSRTPINRNFG 381
Q+ +QY+H NG+IH D+KPENV+ S +CL IKI DFG +K + + G
Sbjct: 328 FYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCL-IKITDFGHSKILGETSLMRTLCG 386
Query: 382 FFSSVAPELYSGNVLTTAY----DMWSVGILMGIGLLGYTPRIIGKRSRRLSVVFTSQEY 437
+ +APE+ +V T Y D WS+G+++ I L GY P + L TS +Y
Sbjct: 387 TPTYLAPEVLV-SVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKY 445
Query: 438 LCI-------SGAALHFFGKCLHTNPSRRLTAAQALNHPWMFD 473
I S AL K L +P R T +AL HPW+ D
Sbjct: 446 NFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQD 488
>AF174135-1|AAD48504.1| 543|Homo sapiens protein kinase CHK2
protein.
Length = 543
Score = 112 bits (269), Expect = 5e-24
Identities = 93/283 (32%), Positives = 143/283 (50%), Gaps = 30/283 (10%)
Query: 215 YLKSLQNFYRDFLPLKLIGSGVYGKVMLIRSNAGKQFVAKTVISQ--YQTNSMEEY---- 268
Y K+L++ +++ K +GSG G+V L + VA +IS+ + S E
Sbjct: 212 YPKALRD---EYIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREADPAL 268
Query: 269 ---STLRILR--NTPNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIY 323
+ + IL+ N P I+K I+ + D ++ V+E + GG LFD+ ++ + E K+Y
Sbjct: 269 NVETEIEILKKLNHPCIIK-IKNFFDAEDYYIVLELMEGGELFDKVVGNKRLKEATCKLY 327
Query: 324 LRQVCSGLQYIHNNGLIHFDIKPENVMCCSL--NCLNIKIIDFGLTKCARSRTPINRNFG 381
Q+ +QY+H NG+IH D+KPENV+ S +CL IKI DFG +K + + G
Sbjct: 328 FYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCL-IKITDFGHSKILGETSLMRTLCG 386
Query: 382 FFSSVAPELYSGNVLTTAY----DMWSVGILMGIGLLGYTPRIIGKRSRRLSVVFTSQEY 437
+ +APE+ +V T Y D WS+G+++ I L GY P + L TS +Y
Sbjct: 387 TPTYLAPEVLV-SVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKY 445
Query: 438 LCI-------SGAALHFFGKCLHTNPSRRLTAAQALNHPWMFD 473
I S AL K L +P R T +AL HPW+ D
Sbjct: 446 NFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQD 488
>AF096279-1|AAD11784.1| 543|Homo sapiens HuCds1 kinase protein.
Length = 543
Score = 112 bits (269), Expect = 5e-24
Identities = 93/283 (32%), Positives = 143/283 (50%), Gaps = 30/283 (10%)
Query: 215 YLKSLQNFYRDFLPLKLIGSGVYGKVMLIRSNAGKQFVAKTVISQ--YQTNSMEEY---- 268
Y K+L++ +++ K +GSG G+V L + VA +IS+ + S E
Sbjct: 212 YPKALRD---EYIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREADPAL 268
Query: 269 ---STLRILR--NTPNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIY 323
+ + IL+ N P I+K I+ + D ++ V+E + GG LFD+ ++ + E K+Y
Sbjct: 269 NVETEIEILKKLNHPCIIK-IKNFFDAEDYYIVLELMEGGELFDKVVGNKRLKEATCKLY 327
Query: 324 LRQVCSGLQYIHNNGLIHFDIKPENVMCCSL--NCLNIKIIDFGLTKCARSRTPINRNFG 381
Q+ +QY+H NG+IH D+KPENV+ S +CL IKI DFG +K + + G
Sbjct: 328 FYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCL-IKITDFGHSKILGETSLMRTLCG 386
Query: 382 FFSSVAPELYSGNVLTTAY----DMWSVGILMGIGLLGYTPRIIGKRSRRLSVVFTSQEY 437
+ +APE+ +V T Y D WS+G+++ I L GY P + L TS +Y
Sbjct: 387 TPTYLAPEVLV-SVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKY 445
Query: 438 LCI-------SGAALHFFGKCLHTNPSRRLTAAQALNHPWMFD 473
I S AL K L +P R T +AL HPW+ D
Sbjct: 446 NFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQD 488
>AF086904-1|AAC83693.1| 543|Homo sapiens protein kinase Chk2
protein.
Length = 543
Score = 112 bits (269), Expect = 5e-24
Identities = 93/283 (32%), Positives = 143/283 (50%), Gaps = 30/283 (10%)
Query: 215 YLKSLQNFYRDFLPLKLIGSGVYGKVMLIRSNAGKQFVAKTVISQ--YQTNSMEEY---- 268
Y K+L++ +++ K +GSG G+V L + VA +IS+ + S E
Sbjct: 212 YPKALRD---EYIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREADPAL 268
Query: 269 ---STLRILR--NTPNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIY 323
+ + IL+ N P I+K I+ + D ++ V+E + GG LFD+ ++ + E K+Y
Sbjct: 269 NVETEIEILKKLNHPCIIK-IKNFFDAEDYYIVLELMEGGELFDKVVGNKRLKEATCKLY 327
Query: 324 LRQVCSGLQYIHNNGLIHFDIKPENVMCCSL--NCLNIKIIDFGLTKCARSRTPINRNFG 381
Q+ +QY+H NG+IH D+KPENV+ S +CL IKI DFG +K + + G
Sbjct: 328 FYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCL-IKITDFGHSKILGETSLMRTLCG 386
Query: 382 FFSSVAPELYSGNVLTTAY----DMWSVGILMGIGLLGYTPRIIGKRSRRLSVVFTSQEY 437
+ +APE+ +V T Y D WS+G+++ I L GY P + L TS +Y
Sbjct: 387 TPTYLAPEVLV-SVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKY 445
Query: 438 LCI-------SGAALHFFGKCLHTNPSRRLTAAQALNHPWMFD 473
I S AL K L +P R T +AL HPW+ D
Sbjct: 446 NFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQD 488
>Z98049-1|CAI20579.1| 733|Homo sapiens ribosomal protein S6 kinase,
90kDa, polypeptide 2 protein.
Length = 733
Score = 111 bits (266), Expect = 1e-23
Identities = 79/252 (31%), Positives = 117/252 (46%), Gaps = 12/252 (4%)
Query: 232 IGSGVYGKVMLIRSNAGKQFVAKTVISQYQTNSMEEYSTLRILRNTPNIVKLIECYSDGL 291
IG G Y A A +I + + + EE L PNI+ L + Y DG
Sbjct: 421 IGVGSYSVCKRCVHKATDTEYAVKIIDKSKRDPSEEIEILLRYGQHPNIITLKDVYDDGK 480
Query: 292 NWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFDIKPENVMC 351
VME + GG L DR + SER+ L + + Y+H+ G++H D+KP N++
Sbjct: 481 FVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLHSQGVVHRDLKPSNILY 540
Query: 352 C--SLNCLNIKIIDFGLTKCARSRTPINRNFGFFSS-VAPELYSGNVLTTAYDMWSVGIL 408
S + +I++ DFG K R+ + + ++ VAPE+ A D+WS+GIL
Sbjct: 541 RDESGSPESIRVCDFGFAKQLRAGNGLLMTPCYTANFVAPEVLKRQGYDAACDIWSLGIL 600
Query: 409 MGIGLLGYTPRIIGKRSRRLSVV--FTSQEYL-------CISGAALHFFGKCLHTNPSRR 459
+ L G+TP G ++ S +Y IS AA K LH +P +R
Sbjct: 601 LYTMLAGFTPFANGPDDTPEEILARIGSGKYALSGGNWDSISDAAKDVVSKMLHVDPHQR 660
Query: 460 LTAAQALNHPWM 471
LTA Q L HPW+
Sbjct: 661 LTAMQVLKHPWV 672
Score = 99.5 bits (237), Expect = 4e-20
Identities = 77/246 (31%), Positives = 120/246 (48%), Gaps = 15/246 (6%)
Query: 229 LKLIGSGVYGKVMLIR----SNAGKQFVAK-----TVISQYQTNSMEEYSTLRILRNTPN 279
LK++G G YGKV L+R S+AG+ + K T+ + + S E L + N P
Sbjct: 62 LKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRVRSKMERDILAEV-NHPF 120
Query: 280 IVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGL 339
IVKL + +++ L GG+LF R +E D+K YL ++ L ++H+ G+
Sbjct: 121 IVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLGI 180
Query: 340 IHFDIKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNF-GFFSSVAPELYSGNVLTT 398
I+ D+KPEN++ +IKI DFGL+K A +F G +APE+ + T
Sbjct: 181 IYRDLKPENILLDEEG--HIKITDFGLSKEAIDHDKRAYSFCGTIEYMAPEVVNRRGHTQ 238
Query: 399 AYDMWSVGILMGIGLLGYTPRIIGKRSRRLSVVFTSQEYL--CISGAALHFFGKCLHTNP 456
+ D WS G+LM L G P R ++++ ++ + +SG A NP
Sbjct: 239 SADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKAKLGMPQFLSGEAQSLLRALFKRNP 298
Query: 457 SRRLTA 462
RL A
Sbjct: 299 CNRLGA 304
>X85106-1|CAA59427.1| 733|Homo sapiens ribosomal S6 kinase protein.
Length = 733
Score = 111 bits (266), Expect = 1e-23
Identities = 79/252 (31%), Positives = 117/252 (46%), Gaps = 12/252 (4%)
Query: 232 IGSGVYGKVMLIRSNAGKQFVAKTVISQYQTNSMEEYSTLRILRNTPNIVKLIECYSDGL 291
IG G Y A A +I + + + EE L PNI+ L + Y DG
Sbjct: 421 IGVGSYSVCKRCVHKATDTEYAVKIIDKSKRDPSEEIEILLRYGQHPNIITLKDVYDDGK 480
Query: 292 NWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFDIKPENVMC 351
VME + GG L DR + SER+ L + + Y+H+ G++H D+KP N++
Sbjct: 481 FVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLHSQGVVHRDLKPSNILY 540
Query: 352 C--SLNCLNIKIIDFGLTKCARSRTPINRNFGFFSS-VAPELYSGNVLTTAYDMWSVGIL 408
S + +I++ DFG K R+ + + ++ VAPE+ A D+WS+GIL
Sbjct: 541 RDESGSPESIRVCDFGFAKQLRAGNGLLMTPCYTANFVAPEVLKRQGYDAACDIWSLGIL 600
Query: 409 MGIGLLGYTPRIIGKRSRRLSVV--FTSQEYL-------CISGAALHFFGKCLHTNPSRR 459
+ L G+TP G ++ S +Y IS AA K LH +P +R
Sbjct: 601 LYTMLAGFTPFANGPDDTPEEILARIGSGKYALSGGNWDSISDAAKDVVSKMLHVDPHQR 660
Query: 460 LTAAQALNHPWM 471
LTA Q L HPW+
Sbjct: 661 LTAMQVLKHPWV 672
Score = 99.5 bits (237), Expect = 4e-20
Identities = 77/246 (31%), Positives = 120/246 (48%), Gaps = 15/246 (6%)
Query: 229 LKLIGSGVYGKVMLIR----SNAGKQFVAK-----TVISQYQTNSMEEYSTLRILRNTPN 279
LK++G G YGKV L+R S+AG+ + K T+ + + S E L + N P
Sbjct: 62 LKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRVRSKMERDILAEV-NHPF 120
Query: 280 IVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGL 339
IVKL + +++ L GG+LF R +E D+K YL ++ L ++H+ G+
Sbjct: 121 IVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLGI 180
Query: 340 IHFDIKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNF-GFFSSVAPELYSGNVLTT 398
I+ D+KPEN++ +IKI DFGL+K A +F G +APE+ + T
Sbjct: 181 IYRDLKPENILLDEEG--HIKITDFGLSKEAIDHDKRAYSFCGTIEYMAPEVVNRRGHTQ 238
Query: 399 AYDMWSVGILMGIGLLGYTPRIIGKRSRRLSVVFTSQEYL--CISGAALHFFGKCLHTNP 456
+ D WS G+LM L G P R ++++ ++ + +SG A NP
Sbjct: 239 SADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKAKLGMPQFLSGEAQSLLRALFKRNP 298
Query: 457 SRRLTA 462
RL A
Sbjct: 299 CNRLGA 304
>BC002363-1|AAH02363.1| 733|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 2 protein.
Length = 733
Score = 111 bits (266), Expect = 1e-23
Identities = 79/252 (31%), Positives = 117/252 (46%), Gaps = 12/252 (4%)
Query: 232 IGSGVYGKVMLIRSNAGKQFVAKTVISQYQTNSMEEYSTLRILRNTPNIVKLIECYSDGL 291
IG G Y A A +I + + + EE L PNI+ L + Y DG
Sbjct: 421 IGVGSYSVCKRCVHKATDTEYAVKIIDKSKRDPSEEIEILLRYGQHPNIITLKDVYDDGK 480
Query: 292 NWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFDIKPENVMC 351
VME + GG L DR + SER+ L + + Y+H+ G++H D+KP N++
Sbjct: 481 FVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLHSQGVVHRDLKPSNILY 540
Query: 352 C--SLNCLNIKIIDFGLTKCARSRTPINRNFGFFSS-VAPELYSGNVLTTAYDMWSVGIL 408
S + +I++ DFG K R+ + + ++ VAPE+ A D+WS+GIL
Sbjct: 541 RDESGSPESIRVCDFGFAKQLRAGNGLLMTPCYTANFVAPEVLKRQGYDAACDIWSLGIL 600
Query: 409 MGIGLLGYTPRIIGKRSRRLSVV--FTSQEYL-------CISGAALHFFGKCLHTNPSRR 459
+ L G+TP G ++ S +Y IS AA K LH +P +R
Sbjct: 601 LYTMLAGFTPFANGPDDTPEEILARIGSGKYALSGGNWDSISDAAKDVVSKMLHVDPHQR 660
Query: 460 LTAAQALNHPWM 471
LTA Q L HPW+
Sbjct: 661 LTAMQVLKHPWV 672
Score = 99.5 bits (237), Expect = 4e-20
Identities = 77/246 (31%), Positives = 120/246 (48%), Gaps = 15/246 (6%)
Query: 229 LKLIGSGVYGKVMLIR----SNAGKQFVAK-----TVISQYQTNSMEEYSTLRILRNTPN 279
LK++G G YGKV L+R S+AG+ + K T+ + + S E L + N P
Sbjct: 62 LKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRVRSKMERDILAEV-NHPF 120
Query: 280 IVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGL 339
IVKL + +++ L GG+LF R +E D+K YL ++ L ++H+ G+
Sbjct: 121 IVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLGI 180
Query: 340 IHFDIKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNF-GFFSSVAPELYSGNVLTT 398
I+ D+KPEN++ +IKI DFGL+K A +F G +APE+ + T
Sbjct: 181 IYRDLKPENILLDEEG--HIKITDFGLSKEAIDHDKRAYSFCGTIEYMAPEVVNRRGHTQ 238
Query: 399 AYDMWSVGILMGIGLLGYTPRIIGKRSRRLSVVFTSQEYL--CISGAALHFFGKCLHTNP 456
+ D WS G+LM L G P R ++++ ++ + +SG A NP
Sbjct: 239 SADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKAKLGMPQFLSGEAQSLLRALFKRNP 298
Query: 457 SRRLTA 462
RL A
Sbjct: 299 CNRLGA 304
>AL022069-2|CAI19651.1| 733|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 2 protein.
Length = 733
Score = 111 bits (266), Expect = 1e-23
Identities = 79/252 (31%), Positives = 117/252 (46%), Gaps = 12/252 (4%)
Query: 232 IGSGVYGKVMLIRSNAGKQFVAKTVISQYQTNSMEEYSTLRILRNTPNIVKLIECYSDGL 291
IG G Y A A +I + + + EE L PNI+ L + Y DG
Sbjct: 421 IGVGSYSVCKRCVHKATDTEYAVKIIDKSKRDPSEEIEILLRYGQHPNIITLKDVYDDGK 480
Query: 292 NWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFDIKPENVMC 351
VME + GG L DR + SER+ L + + Y+H+ G++H D+KP N++
Sbjct: 481 FVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLHSQGVVHRDLKPSNILY 540
Query: 352 C--SLNCLNIKIIDFGLTKCARSRTPINRNFGFFSS-VAPELYSGNVLTTAYDMWSVGIL 408
S + +I++ DFG K R+ + + ++ VAPE+ A D+WS+GIL
Sbjct: 541 RDESGSPESIRVCDFGFAKQLRAGNGLLMTPCYTANFVAPEVLKRQGYDAACDIWSLGIL 600
Query: 409 MGIGLLGYTPRIIGKRSRRLSVV--FTSQEYL-------CISGAALHFFGKCLHTNPSRR 459
+ L G+TP G ++ S +Y IS AA K LH +P +R
Sbjct: 601 LYTMLAGFTPFANGPDDTPEEILARIGSGKYALSGGNWDSISDAAKDVVSKMLHVDPHQR 660
Query: 460 LTAAQALNHPWM 471
LTA Q L HPW+
Sbjct: 661 LTAMQVLKHPWV 672
Score = 99.5 bits (237), Expect = 4e-20
Identities = 77/246 (31%), Positives = 120/246 (48%), Gaps = 15/246 (6%)
Query: 229 LKLIGSGVYGKVMLIR----SNAGKQFVAK-----TVISQYQTNSMEEYSTLRILRNTPN 279
LK++G G YGKV L+R S+AG+ + K T+ + + S E L + N P
Sbjct: 62 LKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRVRSKMERDILAEV-NHPF 120
Query: 280 IVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGL 339
IVKL + +++ L GG+LF R +E D+K YL ++ L ++H+ G+
Sbjct: 121 IVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLGI 180
Query: 340 IHFDIKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNF-GFFSSVAPELYSGNVLTT 398
I+ D+KPEN++ +IKI DFGL+K A +F G +APE+ + T
Sbjct: 181 IYRDLKPENILLDEEG--HIKITDFGLSKEAIDHDKRAYSFCGTIEYMAPEVVNRRGHTQ 238
Query: 399 AYDMWSVGILMGIGLLGYTPRIIGKRSRRLSVVFTSQEYL--CISGAALHFFGKCLHTNP 456
+ D WS G+LM L G P R ++++ ++ + +SG A NP
Sbjct: 239 SADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKAKLGMPQFLSGEAQSLLRALFKRNP 298
Query: 457 SRRLTA 462
RL A
Sbjct: 299 CNRLGA 304
>AB209116-1|BAD92353.1| 806|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 2 isoform b variant protein.
Length = 806
Score = 111 bits (266), Expect = 1e-23
Identities = 79/252 (31%), Positives = 117/252 (46%), Gaps = 12/252 (4%)
Query: 232 IGSGVYGKVMLIRSNAGKQFVAKTVISQYQTNSMEEYSTLRILRNTPNIVKLIECYSDGL 291
IG G Y A A +I + + + EE L PNI+ L + Y DG
Sbjct: 494 IGVGSYSVCKRCVHKATDTEYAVKIIDKSKRDPSEEIEILLRYGQHPNIITLKDVYDDGK 553
Query: 292 NWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFDIKPENVMC 351
VME + GG L DR + SER+ L + + Y+H+ G++H D+KP N++
Sbjct: 554 FVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLHSQGVVHRDLKPSNILY 613
Query: 352 C--SLNCLNIKIIDFGLTKCARSRTPINRNFGFFSS-VAPELYSGNVLTTAYDMWSVGIL 408
S + +I++ DFG K R+ + + ++ VAPE+ A D+WS+GIL
Sbjct: 614 RDESGSPESIRVCDFGFAKQLRAGNGLLMTPCYTANFVAPEVLKRQGYDAACDIWSLGIL 673
Query: 409 MGIGLLGYTPRIIGKRSRRLSVV--FTSQEYL-------CISGAALHFFGKCLHTNPSRR 459
+ L G+TP G ++ S +Y IS AA K LH +P +R
Sbjct: 674 LYTMLAGFTPFANGPDDTPEEILARIGSGKYALSGGNWDSISDAAKDVVSKMLHVDPHQR 733
Query: 460 LTAAQALNHPWM 471
LTA Q L HPW+
Sbjct: 734 LTAMQVLKHPWV 745
Score = 99.5 bits (237), Expect = 4e-20
Identities = 77/246 (31%), Positives = 120/246 (48%), Gaps = 15/246 (6%)
Query: 229 LKLIGSGVYGKVMLIR----SNAGKQFVAK-----TVISQYQTNSMEEYSTLRILRNTPN 279
LK++G G YGKV L+R S+AG+ + K T+ + + S E L + N P
Sbjct: 135 LKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRVRSKMERDILAEV-NHPF 193
Query: 280 IVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGL 339
IVKL + +++ L GG+LF R +E D+K YL ++ L ++H+ G+
Sbjct: 194 IVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLGI 253
Query: 340 IHFDIKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNF-GFFSSVAPELYSGNVLTT 398
I+ D+KPEN++ +IKI DFGL+K A +F G +APE+ + T
Sbjct: 254 IYRDLKPENILLDEEG--HIKITDFGLSKEAIDHDKRAYSFCGTIEYMAPEVVNRRGHTQ 311
Query: 399 AYDMWSVGILMGIGLLGYTPRIIGKRSRRLSVVFTSQEYL--CISGAALHFFGKCLHTNP 456
+ D WS G+LM L G P R ++++ ++ + +SG A NP
Sbjct: 312 SADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKAKLGMPQFLSGEAQSLLRALFKRNP 371
Query: 457 SRRLTA 462
RL A
Sbjct: 372 CNRLGA 377
>AF217975-1|AAG17218.1| 322|Homo sapiens unknown protein.
Length = 322
Score = 110 bits (265), Expect = 1e-23
Identities = 90/268 (33%), Positives = 134/268 (50%), Gaps = 27/268 (10%)
Query: 230 KLIGSGVYGKVMLIRSNAGKQFVAKTVISQ--YQTNSMEEY-------STLRILR--NTP 278
K +GSG G+V L + VA +IS+ + S E + + IL+ N P
Sbjct: 3 KTLGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREADPALNVETEIEILKKLNHP 62
Query: 279 NIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNG 338
I+K I+ + D ++ V+E + GG LFD+ ++ + E K+Y Q+ +QY+H NG
Sbjct: 63 CIIK-IKNFFDAEDYYIVLELMEGGELFDKVVGNKRLKEATCKLYFYQMLLAVQYLHENG 121
Query: 339 LIHFDIKPENVMCCSL--NCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVL 396
+IH D+KPENV+ S +CL IKI DFG +K + + G + +APE+ +V
Sbjct: 122 IIHRDLKPENVLLSSQEEDCL-IKITDFGHSKILGETSLMRTLCGTPTYLAPEVLV-SVG 179
Query: 397 TTAY----DMWSVGILMGIGLLGYTPRIIGKRSRRLSVVFTSQEYLCI-------SGAAL 445
T Y D WS+G+++ I L GY P + L TS +Y I S AL
Sbjct: 180 TAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNFIPEVWAEVSEKAL 239
Query: 446 HFFGKCLHTNPSRRLTAAQALNHPWMFD 473
K L +P R T +AL HPW+ D
Sbjct: 240 DLVKKLLVVDPKARFTTEEALRHPWLQD 267
>U08316-1|AAA81952.1| 740|Homo sapiens insulin-stimulated protein
kinase 1 protein.
Length = 740
Score = 110 bits (264), Expect = 2e-23
Identities = 75/252 (29%), Positives = 114/252 (45%), Gaps = 12/252 (4%)
Query: 232 IGSGVYGKVMLIRSNAGKQFVAKTVISQYQTNSMEEYSTLRILRNTPNIVKLIECYSDGL 291
IG G Y A A +I + + + EE L PNI+ L + Y DG
Sbjct: 428 IGVGSYSVCKRCIHKATNMEFAVKIIDKSKRDPTEEIEILLRYGQHPNIITLKDVYDDGK 487
Query: 292 NWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFDIKPENVMC 351
V E + GG L D+ + SER+ L + ++Y+H G++H D+KP N++
Sbjct: 488 YVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQGVVHRDLKPSNILY 547
Query: 352 C--SLNCLNIKIIDFGLTKCARSRTPINRNFGFFSS-VAPELYSGNVLTTAYDMWSVGIL 408
S N +I+I DFG K R+ + + ++ VAPE+ A D+WS+G+L
Sbjct: 548 VDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDAACDIWSLGVL 607
Query: 409 MGIGLLGYTPRIIGKRSRRLSVV---------FTSQEYLCISGAALHFFGKCLHTNPSRR 459
+ L GYTP G ++ + + +S A K LH +P +R
Sbjct: 608 LYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNSVSDTAKDLVSKMLHVDPHQR 667
Query: 460 LTAAQALNHPWM 471
LTAA L HPW+
Sbjct: 668 LTAALVLRHPWI 679
Score = 92.7 bits (220), Expect = 4e-18
Identities = 69/245 (28%), Positives = 117/245 (47%), Gaps = 13/245 (5%)
Query: 229 LKLIGSGVYGKVMLIRSNAG---KQFVAKTVISQYQTNSMEEYST-----LRILRNTPNI 280
LK++G G +GKV L++ +G +Q A V+ + + T + + N P I
Sbjct: 71 LKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKMERDILVEVNHPFI 130
Query: 281 VKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLI 340
VKL + +++ L GG+LF R +E D+K YL ++ L ++H+ G+I
Sbjct: 131 VKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLGII 190
Query: 341 HFDIKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNF-GFFSSVAPELYSGNVLTTA 399
+ D+KPEN++ +IK+ DFGL+K + +F G +APE+ + T +
Sbjct: 191 YRDLKPENILLDEEG--HIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVVNRRGHTQS 248
Query: 400 YDMWSVGILMGIGLLGYTPRIIGKRSRRLSVVFTSQEYL--CISGAALHFFGKCLHTNPS 457
D WS G+LM L G P R ++++ ++ + +S A NP+
Sbjct: 249 ADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEAQSLLRMLFKRNPA 308
Query: 458 RRLTA 462
RL A
Sbjct: 309 NRLGA 313
>L24959-1|AAA18251.1| 473|Homo sapiens calcium/calmodulin dependent
protein kinase protein.
Length = 473
Score = 110 bits (264), Expect = 2e-23
Identities = 68/202 (33%), Positives = 99/202 (49%), Gaps = 8/202 (3%)
Query: 278 PNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNN 337
PNI+KL E + V+E + GG LFDR SERD ++Q+ + Y+H N
Sbjct: 99 PNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAADAVKQILEAVAYLHEN 158
Query: 338 GLIHFDIKPENVMCCS-LNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVL 396
G++H D+KPEN++ + +KI DFGL+K + + G APE+ G
Sbjct: 159 GIVHRDLKPENLLYATPAPDAPLKIADFGLSKIVEHQVLMKTVCGTPGYCAPEILRGCAY 218
Query: 397 TTAYDMWSVGILMGIGLLGYTP-------RIIGKRSRRLSVVFTSQEYLCISGAALHFFG 449
DMWSVGI+ I L G+ P + + +R F S + +S A
Sbjct: 219 GPEVDMWSVGIITYILLCGFEPFYDERGDQFMFRRILNCEYYFISPWWDEVSLNAKDLVR 278
Query: 450 KCLHTNPSRRLTAAQALNHPWM 471
K + +P +RLT QAL HPW+
Sbjct: 279 KLIVLDPKKRLTTFQALQHPWV 300
>L17000-1|AAA35639.1| 473|Homo sapiens calcium/calmodulin-dependent
protein kinase protein.
Length = 473
Score = 110 bits (264), Expect = 2e-23
Identities = 68/202 (33%), Positives = 99/202 (49%), Gaps = 8/202 (3%)
Query: 278 PNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNN 337
PNI+KL E + V+E + GG LFDR SERD ++Q+ + Y+H N
Sbjct: 99 PNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAADAVKQILEAVAYLHEN 158
Query: 338 GLIHFDIKPENVMCCS-LNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVL 396
G++H D+KPEN++ + +KI DFGL+K + + G APE+ G
Sbjct: 159 GIVHRDLKPENLLYATPAPDAPLKIADFGLSKIVEHQVLMKTVCGTPGYCAPEILRGCAY 218
Query: 397 TTAYDMWSVGILMGIGLLGYTP-------RIIGKRSRRLSVVFTSQEYLCISGAALHFFG 449
DMWSVGI+ I L G+ P + + +R F S + +S A
Sbjct: 219 GPEVDMWSVGIITYILLCGFEPFYDERGDQFMFRRILNCEYYFISPWWDEVSLNAKDLVR 278
Query: 450 KCLHTNPSRRLTAAQALNHPWM 471
K + +P +RLT QAL HPW+
Sbjct: 279 KLIVLDPKKRLTTFQALQHPWV 300
>D30742-1|BAA06403.1| 473|Homo sapiens calmodulin-dependent protein
kinase IV protein.
Length = 473
Score = 110 bits (264), Expect = 2e-23
Identities = 68/202 (33%), Positives = 99/202 (49%), Gaps = 8/202 (3%)
Query: 278 PNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNN 337
PNI+KL E + V+E + GG LFDR SERD ++Q+ + Y+H N
Sbjct: 99 PNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAADAVKQILEAVAYLHEN 158
Query: 338 GLIHFDIKPENVMCCS-LNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVL 396
G++H D+KPEN++ + +KI DFGL+K + + G APE+ G
Sbjct: 159 GIVHRDLKPENLLYATPAPDAPLKIADFGLSKIVEHQVLMKTVCGTPGYCAPEILRGCAY 218
Query: 397 TTAYDMWSVGILMGIGLLGYTP-------RIIGKRSRRLSVVFTSQEYLCISGAALHFFG 449
DMWSVGI+ I L G+ P + + +R F S + +S A
Sbjct: 219 GPEVDMWSVGIITYILLCGFEPFYDERGDQFMFRRILNCEYYFISPWWDEVSLNAKDLVR 278
Query: 450 KCLHTNPSRRLTAAQALNHPWM 471
K + +P +RLT QAL HPW+
Sbjct: 279 KLIVLDPKKRLTTFQALQHPWV 300
>BC096303-1|AAH96303.1| 740|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 protein.
Length = 740
Score = 110 bits (264), Expect = 2e-23
Identities = 75/252 (29%), Positives = 114/252 (45%), Gaps = 12/252 (4%)
Query: 232 IGSGVYGKVMLIRSNAGKQFVAKTVISQYQTNSMEEYSTLRILRNTPNIVKLIECYSDGL 291
IG G Y A A +I + + + EE L PNI+ L + Y DG
Sbjct: 428 IGVGSYSVCKRCIHKATNMEFAVKIIDKSKRDPTEEIEILLRYGQHPNIITLKDVYDDGK 487
Query: 292 NWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFDIKPENVMC 351
V E + GG L D+ + SER+ L + ++Y+H G++H D+KP N++
Sbjct: 488 YVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQGVVHRDLKPSNILY 547
Query: 352 C--SLNCLNIKIIDFGLTKCARSRTPINRNFGFFSS-VAPELYSGNVLTTAYDMWSVGIL 408
S N +I+I DFG K R+ + + ++ VAPE+ A D+WS+G+L
Sbjct: 548 VDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDAACDIWSLGVL 607
Query: 409 MGIGLLGYTPRIIGKRSRRLSVV---------FTSQEYLCISGAALHFFGKCLHTNPSRR 459
+ L GYTP G ++ + + +S A K LH +P +R
Sbjct: 608 LYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNSVSDTAKDLVSKMLHVDPHQR 667
Query: 460 LTAAQALNHPWM 471
LTAA L HPW+
Sbjct: 668 LTAALVLRHPWI 679
Score = 91.9 bits (218), Expect = 7e-18
Identities = 69/245 (28%), Positives = 116/245 (47%), Gaps = 13/245 (5%)
Query: 229 LKLIGSGVYGKVMLIRSNAG---KQFVAKTVISQYQTNSMEEYST-----LRILRNTPNI 280
LK++G G +GKV L++ G +Q A V+ + + T + + N P I
Sbjct: 71 LKVLGQGSFGKVFLVKKILGSDARQLYAMKVLKKATLKVRDRVRTKMERDILVEVNHPFI 130
Query: 281 VKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLI 340
VKL + +++ L GG+LF R +E D+K YL ++ L ++H+ G+I
Sbjct: 131 VKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLGII 190
Query: 341 HFDIKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNF-GFFSSVAPELYSGNVLTTA 399
+ D+KPEN++ +IK+ DFGL+K + +F G +APE+ + T +
Sbjct: 191 YRDLKPENILLDEEG--HIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVVNRRGHTQS 248
Query: 400 YDMWSVGILMGIGLLGYTPRIIGKRSRRLSVVFTSQEYL--CISGAALHFFGKCLHTNPS 457
D WS G+LM L G P R ++++ ++ + +S A NP+
Sbjct: 249 ADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEAQSLLRMLFKRNPA 308
Query: 458 RRLTA 462
RL A
Sbjct: 309 NRLGA 313
>BC096302-1|AAH96302.1| 740|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 protein.
Length = 740
Score = 110 bits (264), Expect = 2e-23
Identities = 75/252 (29%), Positives = 114/252 (45%), Gaps = 12/252 (4%)
Query: 232 IGSGVYGKVMLIRSNAGKQFVAKTVISQYQTNSMEEYSTLRILRNTPNIVKLIECYSDGL 291
IG G Y A A +I + + + EE L PNI+ L + Y DG
Sbjct: 428 IGVGSYSVCKRCIHKATNMEFAVKIIDKSKRDPTEEIEILLRYGQHPNIITLKDVYDDGK 487
Query: 292 NWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFDIKPENVMC 351
V E + GG L D+ + SER+ L + ++Y+H G++H D+KP N++
Sbjct: 488 YVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQGVVHRDLKPSNILY 547
Query: 352 C--SLNCLNIKIIDFGLTKCARSRTPINRNFGFFSS-VAPELYSGNVLTTAYDMWSVGIL 408
S N +I+I DFG K R+ + + ++ VAPE+ A D+WS+G+L
Sbjct: 548 VDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDAACDIWSLGVL 607
Query: 409 MGIGLLGYTPRIIGKRSRRLSVV---------FTSQEYLCISGAALHFFGKCLHTNPSRR 459
+ L GYTP G ++ + + +S A K LH +P +R
Sbjct: 608 LYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNSVSDTAKDLVSKMLHVDPHQR 667
Query: 460 LTAAQALNHPWM 471
LTAA L HPW+
Sbjct: 668 LTAALVLRHPWI 679
Score = 92.7 bits (220), Expect = 4e-18
Identities = 69/245 (28%), Positives = 117/245 (47%), Gaps = 13/245 (5%)
Query: 229 LKLIGSGVYGKVMLIRSNAG---KQFVAKTVISQYQTNSMEEYST-----LRILRNTPNI 280
LK++G G +GKV L++ +G +Q A V+ + + T + + N P I
Sbjct: 71 LKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKMERDILVEVNHPFI 130
Query: 281 VKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLI 340
VKL + +++ L GG+LF R +E D+K YL ++ L ++H+ G+I
Sbjct: 131 VKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLGII 190
Query: 341 HFDIKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNF-GFFSSVAPELYSGNVLTTA 399
+ D+KPEN++ +IK+ DFGL+K + +F G +APE+ + T +
Sbjct: 191 YRDLKPENILLDEEG--HIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVVNRRGHTQS 248
Query: 400 YDMWSVGILMGIGLLGYTPRIIGKRSRRLSVVFTSQEYL--CISGAALHFFGKCLHTNPS 457
D WS G+LM L G P R ++++ ++ + +S A NP+
Sbjct: 249 ADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEAQSLLRMLFKRNPA 308
Query: 458 RRLTA 462
RL A
Sbjct: 309 NRLGA 313
>BC096301-1|AAH96301.1| 740|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 protein.
Length = 740
Score = 110 bits (264), Expect = 2e-23
Identities = 75/252 (29%), Positives = 114/252 (45%), Gaps = 12/252 (4%)
Query: 232 IGSGVYGKVMLIRSNAGKQFVAKTVISQYQTNSMEEYSTLRILRNTPNIVKLIECYSDGL 291
IG G Y A A +I + + + EE L PNI+ L + Y DG
Sbjct: 428 IGVGSYSVCKRCIHKATNMEFAVKIIDKSKRDPTEEIEILLRYGQHPNIITLKDVYDDGK 487
Query: 292 NWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFDIKPENVMC 351
V E + GG L D+ + SER+ L + ++Y+H G++H D+KP N++
Sbjct: 488 YVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQGVVHRDLKPSNILY 547
Query: 352 C--SLNCLNIKIIDFGLTKCARSRTPINRNFGFFSS-VAPELYSGNVLTTAYDMWSVGIL 408
S N +I+I DFG K R+ + + ++ VAPE+ A D+WS+G+L
Sbjct: 548 VDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDAACDIWSLGVL 607
Query: 409 MGIGLLGYTPRIIGKRSRRLSVV---------FTSQEYLCISGAALHFFGKCLHTNPSRR 459
+ L GYTP G ++ + + +S A K LH +P +R
Sbjct: 608 LYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNSVSDTAKDLVSKMLHVDPHQR 667
Query: 460 LTAAQALNHPWM 471
LTAA L HPW+
Sbjct: 668 LTAALVLRHPWI 679
Score = 92.7 bits (220), Expect = 4e-18
Identities = 69/245 (28%), Positives = 117/245 (47%), Gaps = 13/245 (5%)
Query: 229 LKLIGSGVYGKVMLIRSNAG---KQFVAKTVISQYQTNSMEEYST-----LRILRNTPNI 280
LK++G G +GKV L++ +G +Q A V+ + + T + + N P I
Sbjct: 71 LKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKMERDILVEVNHPFI 130
Query: 281 VKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLI 340
VKL + +++ L GG+LF R +E D+K YL ++ L ++H+ G+I
Sbjct: 131 VKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLGII 190
Query: 341 HFDIKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNF-GFFSSVAPELYSGNVLTTA 399
+ D+KPEN++ +IK+ DFGL+K + +F G +APE+ + T +
Sbjct: 191 YRDLKPENILLDEEG--HIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVVNRRGHTQS 248
Query: 400 YDMWSVGILMGIGLLGYTPRIIGKRSRRLSVVFTSQEYL--CISGAALHFFGKCLHTNPS 457
D WS G+LM L G P R ++++ ++ + +S A NP+
Sbjct: 249 ADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEAQSLLRMLFKRNPA 308
Query: 458 RRLTA 462
RL A
Sbjct: 309 NRLGA 313
>BC025687-1|AAH25687.1| 473|Homo sapiens
calcium/calmodulin-dependent protein kinase IV protein.
Length = 473
Score = 110 bits (264), Expect = 2e-23
Identities = 68/202 (33%), Positives = 99/202 (49%), Gaps = 8/202 (3%)
Query: 278 PNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNN 337
PNI+KL E + V+E + GG LFDR SERD ++Q+ + Y+H N
Sbjct: 99 PNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAADAVKQILEAVAYLHEN 158
Query: 338 GLIHFDIKPENVMCCS-LNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVL 396
G++H D+KPEN++ + +KI DFGL+K + + G APE+ G
Sbjct: 159 GIVHRDLKPENLLYATPAPDAPLKIADFGLSKIVEHQVLMKTVCGTPGYCAPEILRGCAY 218
Query: 397 TTAYDMWSVGILMGIGLLGYTP-------RIIGKRSRRLSVVFTSQEYLCISGAALHFFG 449
DMWSVGI+ I L G+ P + + +R F S + +S A
Sbjct: 219 GPEVDMWSVGIITYILLCGFEPFYDERGDQFMFRRILNCEYYFISPWWDEVSLNAKDLVR 278
Query: 450 KCLHTNPSRRLTAAQALNHPWM 471
K + +P +RLT QAL HPW+
Sbjct: 279 KLIVLDPKKRLTTFQALQHPWV 300
>BC016695-1|AAH16695.2| 503|Homo sapiens CAMK4 protein protein.
Length = 503
Score = 110 bits (264), Expect = 2e-23
Identities = 68/202 (33%), Positives = 99/202 (49%), Gaps = 8/202 (3%)
Query: 278 PNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNN 337
PNI+KL E + V+E + GG LFDR SERD ++Q+ + Y+H N
Sbjct: 129 PNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAADAVKQILEAVAYLHEN 188
Query: 338 GLIHFDIKPENVMCCS-LNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVL 396
G++H D+KPEN++ + +KI DFGL+K + + G APE+ G
Sbjct: 189 GIVHRDLKPENLLYATPAPDAPLKIADFGLSKIVEHQVLMKTVCGTPGYCAPEILRGCAY 248
Query: 397 TTAYDMWSVGILMGIGLLGYTP-------RIIGKRSRRLSVVFTSQEYLCISGAALHFFG 449
DMWSVGI+ I L G+ P + + +R F S + +S A
Sbjct: 249 GPEVDMWSVGIITYILLCGFEPFYDERGDQFMFRRILNCEYYFISPWWDEVSLNAKDLVR 308
Query: 450 KCLHTNPSRRLTAAQALNHPWM 471
K + +P +RLT QAL HPW+
Sbjct: 309 KLIVLDPKKRLTTFQALQHPWV 330
>AL807772-3|CAI39687.1| 740|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 protein.
Length = 740
Score = 110 bits (264), Expect = 2e-23
Identities = 75/252 (29%), Positives = 114/252 (45%), Gaps = 12/252 (4%)
Query: 232 IGSGVYGKVMLIRSNAGKQFVAKTVISQYQTNSMEEYSTLRILRNTPNIVKLIECYSDGL 291
IG G Y A A +I + + + EE L PNI+ L + Y DG
Sbjct: 428 IGVGSYSVCKRCIHKATNMEFAVKIIDKSKRDPTEEIEILLRYGQHPNIITLKDVYDDGK 487
Query: 292 NWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFDIKPENVMC 351
V E + GG L D+ + SER+ L + ++Y+H G++H D+KP N++
Sbjct: 488 YVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQGVVHRDLKPSNILY 547
Query: 352 C--SLNCLNIKIIDFGLTKCARSRTPINRNFGFFSS-VAPELYSGNVLTTAYDMWSVGIL 408
S N +I+I DFG K R+ + + ++ VAPE+ A D+WS+G+L
Sbjct: 548 VDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDAACDIWSLGVL 607
Query: 409 MGIGLLGYTPRIIGKRSRRLSVV---------FTSQEYLCISGAALHFFGKCLHTNPSRR 459
+ L GYTP G ++ + + +S A K LH +P +R
Sbjct: 608 LYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNSVSDTAKDLVSKMLHVDPHQR 667
Query: 460 LTAAQALNHPWM 471
LTAA L HPW+
Sbjct: 668 LTAALVLRHPWI 679
Score = 92.7 bits (220), Expect = 4e-18
Identities = 69/245 (28%), Positives = 117/245 (47%), Gaps = 13/245 (5%)
Query: 229 LKLIGSGVYGKVMLIRSNAG---KQFVAKTVISQYQTNSMEEYST-----LRILRNTPNI 280
LK++G G +GKV L++ +G +Q A V+ + + T + + N P I
Sbjct: 71 LKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKMERDILVEVNHPFI 130
Query: 281 VKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLI 340
VKL + +++ L GG+LF R +E D+K YL ++ L ++H+ G+I
Sbjct: 131 VKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLGII 190
Query: 341 HFDIKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNF-GFFSSVAPELYSGNVLTTA 399
+ D+KPEN++ +IK+ DFGL+K + +F G +APE+ + T +
Sbjct: 191 YRDLKPENILLDEEG--HIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVVNRRGHTQS 248
Query: 400 YDMWSVGILMGIGLLGYTPRIIGKRSRRLSVVFTSQEYL--CISGAALHFFGKCLHTNPS 457
D WS G+LM L G P R ++++ ++ + +S A NP+
Sbjct: 249 ADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEAQSLLRMLFKRNPA 308
Query: 458 RRLTA 462
RL A
Sbjct: 309 NRLGA 313
>AL732366-2|CAI40548.1| 740|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 protein.
Length = 740
Score = 110 bits (264), Expect = 2e-23
Identities = 75/252 (29%), Positives = 114/252 (45%), Gaps = 12/252 (4%)
Query: 232 IGSGVYGKVMLIRSNAGKQFVAKTVISQYQTNSMEEYSTLRILRNTPNIVKLIECYSDGL 291
IG G Y A A +I + + + EE L PNI+ L + Y DG
Sbjct: 428 IGVGSYSVCKRCIHKATNMEFAVKIIDKSKRDPTEEIEILLRYGQHPNIITLKDVYDDGK 487
Query: 292 NWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFDIKPENVMC 351
V E + GG L D+ + SER+ L + ++Y+H G++H D+KP N++
Sbjct: 488 YVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQGVVHRDLKPSNILY 547
Query: 352 C--SLNCLNIKIIDFGLTKCARSRTPINRNFGFFSS-VAPELYSGNVLTTAYDMWSVGIL 408
S N +I+I DFG K R+ + + ++ VAPE+ A D+WS+G+L
Sbjct: 548 VDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDAACDIWSLGVL 607
Query: 409 MGIGLLGYTPRIIGKRSRRLSVV---------FTSQEYLCISGAALHFFGKCLHTNPSRR 459
+ L GYTP G ++ + + +S A K LH +P +R
Sbjct: 608 LYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNSVSDTAKDLVSKMLHVDPHQR 667
Query: 460 LTAAQALNHPWM 471
LTAA L HPW+
Sbjct: 668 LTAALVLRHPWI 679
Score = 92.7 bits (220), Expect = 4e-18
Identities = 69/245 (28%), Positives = 117/245 (47%), Gaps = 13/245 (5%)
Query: 229 LKLIGSGVYGKVMLIRSNAG---KQFVAKTVISQYQTNSMEEYST-----LRILRNTPNI 280
LK++G G +GKV L++ +G +Q A V+ + + T + + N P I
Sbjct: 71 LKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKMERDILVEVNHPFI 130
Query: 281 VKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLI 340
VKL + +++ L GG+LF R +E D+K YL ++ L ++H+ G+I
Sbjct: 131 VKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLGII 190
Query: 341 HFDIKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNF-GFFSSVAPELYSGNVLTTA 399
+ D+KPEN++ +IK+ DFGL+K + +F G +APE+ + T +
Sbjct: 191 YRDLKPENILLDEEG--HIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVVNRRGHTQS 248
Query: 400 YDMWSVGILMGIGLLGYTPRIIGKRSRRLSVVFTSQEYL--CISGAALHFFGKCLHTNPS 457
D WS G+LM L G P R ++++ ++ + +S A NP+
Sbjct: 249 ADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEAQSLLRMLFKRNPA 308
Query: 458 RRLTA 462
RL A
Sbjct: 309 NRLGA 313
>AL670729-4|CAH71670.2| 2582|Homo sapiens obscurin, cytoskeletal
calmodulin and titin-interacting RhoGEF protein.
Length = 2582
Score = 110 bits (264), Expect = 2e-23
Identities = 78/282 (27%), Positives = 134/282 (47%), Gaps = 19/282 (6%)
Query: 207 EPLITSPQYLKSLQNFYRDFLPLKLIGSGVYGKVMLIRSNAGKQFVAKTVISQYQTNSME 266
EP + + L +FY + IG GV+G V ++ K A I +
Sbjct: 1068 EPDSEKQSHRRKLHSFYE---VKEEIGRGVFGFVKRVQHKGNKILCAAKFIPLRSRTRAQ 1124
Query: 267 EYSTLRILR--NTPNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYL 324
Y IL + P + L++ + + ++E L DR ++E ++K+Y+
Sbjct: 1125 AYRERDILAALSHPLVTGLLDQFETRKTLILILELCSSEELLDRLYRKGVVTEAEVKVYI 1184
Query: 325 RQVCSGLQYIHNNGLIHFDIKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNFGFFS 384
+Q+ GL Y+H++G++H DIKP N++ +IKI DFG A++ TP F +
Sbjct: 1185 QQLVEGLHYLHSHGVLHLDIKPSNILMVHPAREDIKICDFGF---AQNITPAELQFSQYG 1241
Query: 385 S---VAPELYSGNVLTTAYDMWSVGILMGIGLLGYTPRIIGK--RSRRLSVV-----FTS 434
S V+PE+ N ++ A D+W++G++ + L +P G+ R+ L+V+ ++S
Sbjct: 1242 SPEFVSPEIIQQNPVSEASDIWAMGVISYLSLTCSSP-FAGESDRATLLNVLEGRVSWSS 1300
Query: 435 QEYLCISGAALHFFGKCLHTNPSRRLTAAQALNHPWMFDTCP 476
+S A F L P R +AAQ L+HPW + P
Sbjct: 1301 PMAAHLSEDAKDFIKATLQRAPQARPSAAQCLSHPWFLKSMP 1342
Score = 80.6 bits (190), Expect = 2e-14
Identities = 61/223 (27%), Positives = 101/223 (45%), Gaps = 12/223 (5%)
Query: 261 QTNSMEEYSTLRILRNTPNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDI 320
+T + EY L+ LR+ P++ +L Y + V ++E G L SE ++
Sbjct: 2326 KTAVLREYEALKGLRH-PHLAQLHAAYLSPRHLVLILELCSGPELLPCLAERASYSESEV 2384
Query: 321 KIYLRQVCSGLQYIHNNGLIHFDIKPENVMCCSLNCLNIKIIDFGLTKCARSR--TPINR 378
K YL Q+ S QY+HN ++H D++ EN++ N L K++D G + P ++
Sbjct: 2385 KDYLWQMLSATQYLHNQHILHLDLRSENMIITEYNLL--KVVDLGNAQSLSQEKVLPSDK 2442
Query: 379 NFGFFSSVAPELYSGNVLTTAYDMWSVGILMGIGLLG-YTPRIIG----KRSRRLSVVFT 433
+ ++ EL G D+W++G+ I L Y G +R R +V
Sbjct: 2443 FKDYLETM--ELLEGQGAVPQTDIWAIGVTAFIMLSAEYPVSSEGARDLQRGLRKGLVRL 2500
Query: 434 SQEYLCISGAALHFFGKCLHTNPSRRLTAAQALNHPWMFDTCP 476
S+ Y +SG A+ F L P R A+ L PW+ + P
Sbjct: 2501 SRCYAGLSGGAVAFLRSTLCAQPWGRPCASSCLQCPWLTEEGP 2543
>AL353593-4|CAM27610.1| 2582|Homo sapiens obscurin, cytoskeletal
calmodulin and titin-interacting RhoGEF protein.
Length = 2582
Score = 110 bits (264), Expect = 2e-23
Identities = 78/282 (27%), Positives = 134/282 (47%), Gaps = 19/282 (6%)
Query: 207 EPLITSPQYLKSLQNFYRDFLPLKLIGSGVYGKVMLIRSNAGKQFVAKTVISQYQTNSME 266
EP + + L +FY + IG GV+G V ++ K A I +
Sbjct: 1068 EPDSEKQSHRRKLHSFYE---VKEEIGRGVFGFVKRVQHKGNKILCAAKFIPLRSRTRAQ 1124
Query: 267 EYSTLRILR--NTPNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYL 324
Y IL + P + L++ + + ++E L DR ++E ++K+Y+
Sbjct: 1125 AYRERDILAALSHPLVTGLLDQFETRKTLILILELCSSEELLDRLYRKGVVTEAEVKVYI 1184
Query: 325 RQVCSGLQYIHNNGLIHFDIKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNFGFFS 384
+Q+ GL Y+H++G++H DIKP N++ +IKI DFG A++ TP F +
Sbjct: 1185 QQLVEGLHYLHSHGVLHLDIKPSNILMVHPAREDIKICDFGF---AQNITPAELQFSQYG 1241
Query: 385 S---VAPELYSGNVLTTAYDMWSVGILMGIGLLGYTPRIIGK--RSRRLSVV-----FTS 434
S V+PE+ N ++ A D+W++G++ + L +P G+ R+ L+V+ ++S
Sbjct: 1242 SPEFVSPEIIQQNPVSEASDIWAMGVISYLSLTCSSP-FAGESDRATLLNVLEGRVSWSS 1300
Query: 435 QEYLCISGAALHFFGKCLHTNPSRRLTAAQALNHPWMFDTCP 476
+S A F L P R +AAQ L+HPW + P
Sbjct: 1301 PMAAHLSEDAKDFIKATLQRAPQARPSAAQCLSHPWFLKSMP 1342
Score = 80.6 bits (190), Expect = 2e-14
Identities = 61/223 (27%), Positives = 101/223 (45%), Gaps = 12/223 (5%)
Query: 261 QTNSMEEYSTLRILRNTPNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDI 320
+T + EY L+ LR+ P++ +L Y + V ++E G L SE ++
Sbjct: 2326 KTAVLREYEALKGLRH-PHLAQLHAAYLSPRHLVLILELCSGPELLPCLAERASYSESEV 2384
Query: 321 KIYLRQVCSGLQYIHNNGLIHFDIKPENVMCCSLNCLNIKIIDFGLTKCARSR--TPINR 378
K YL Q+ S QY+HN ++H D++ EN++ N L K++D G + P ++
Sbjct: 2385 KDYLWQMLSATQYLHNQHILHLDLRSENMIITEYNLL--KVVDLGNAQSLSQEKVLPSDK 2442
Query: 379 NFGFFSSVAPELYSGNVLTTAYDMWSVGILMGIGLLG-YTPRIIG----KRSRRLSVVFT 433
+ ++ EL G D+W++G+ I L Y G +R R +V
Sbjct: 2443 FKDYLETM--ELLEGQGAVPQTDIWAIGVTAFIMLSAEYPVSSEGARDLQRGLRKGLVRL 2500
Query: 434 SQEYLCISGAALHFFGKCLHTNPSRRLTAAQALNHPWMFDTCP 476
S+ Y +SG A+ F L P R A+ L PW+ + P
Sbjct: 2501 SRCYAGLSGGAVAFLRSTLCAQPWGRPCASSCLQCPWLTEEGP 2543
>AB208933-1|BAD92170.1| 806|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 variant protein.
Length = 806
Score = 110 bits (264), Expect = 2e-23
Identities = 75/252 (29%), Positives = 114/252 (45%), Gaps = 12/252 (4%)
Query: 232 IGSGVYGKVMLIRSNAGKQFVAKTVISQYQTNSMEEYSTLRILRNTPNIVKLIECYSDGL 291
IG G Y A A +I + + + EE L PNI+ L + Y DG
Sbjct: 494 IGVGSYSVCKRCIHKATNMEFAVKIIDKSKRDPTEEIEILLRYGQHPNIITLKDVYDDGK 553
Query: 292 NWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFDIKPENVMC 351
V E + GG L D+ + SER+ L + ++Y+H G++H D+KP N++
Sbjct: 554 YVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQGVVHRDLKPSNILY 613
Query: 352 C--SLNCLNIKIIDFGLTKCARSRTPINRNFGFFSS-VAPELYSGNVLTTAYDMWSVGIL 408
S N +I+I DFG K R+ + + ++ VAPE+ A D+WS+G+L
Sbjct: 614 VDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDAACDIWSLGVL 673
Query: 409 MGIGLLGYTPRIIGKRSRRLSVV---------FTSQEYLCISGAALHFFGKCLHTNPSRR 459
+ L GYTP G ++ + + +S A K LH +P +R
Sbjct: 674 LYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNSVSDTAKDLVSKMLHVDPHQR 733
Query: 460 LTAAQALNHPWM 471
LTAA L HPW+
Sbjct: 734 LTAALVLRHPWI 745
Score = 92.7 bits (220), Expect = 4e-18
Identities = 69/245 (28%), Positives = 117/245 (47%), Gaps = 13/245 (5%)
Query: 229 LKLIGSGVYGKVMLIRSNAG---KQFVAKTVISQYQTNSMEEYST-----LRILRNTPNI 280
LK++G G +GKV L++ +G +Q A V+ + + T + + N P I
Sbjct: 138 LKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKMERDILVEVNHPFI 197
Query: 281 VKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLI 340
VKL + +++ L GG+LF R +E D+K YL ++ L ++H+ G+I
Sbjct: 198 VKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLGII 257
Query: 341 HFDIKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNF-GFFSSVAPELYSGNVLTTA 399
+ D+KPEN++ +IK+ DFGL+K + +F G +APE+ + T +
Sbjct: 258 YRDLKPENILLDEEG--HIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVVNRRGHTQS 315
Query: 400 YDMWSVGILMGIGLLGYTPRIIGKRSRRLSVVFTSQEYL--CISGAALHFFGKCLHTNPS 457
D WS G+LM L G P R ++++ ++ + +S A NP+
Sbjct: 316 ADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEAQSLLRMLFKRNPA 375
Query: 458 RRLTA 462
RL A
Sbjct: 376 NRLGA 380
>AB102662-1|BAC81131.1| 726|Homo sapiens RPS6KA3 protein.
Length = 726
Score = 110 bits (264), Expect = 2e-23
Identities = 75/252 (29%), Positives = 114/252 (45%), Gaps = 12/252 (4%)
Query: 232 IGSGVYGKVMLIRSNAGKQFVAKTVISQYQTNSMEEYSTLRILRNTPNIVKLIECYSDGL 291
IG G Y A A +I + + + EE L PNI+ L + Y DG
Sbjct: 414 IGVGSYSVCKRCIHKATNMEFAVKIIDKSKRDPTEEIEILLRYGQHPNIITLKDVYDDGK 473
Query: 292 NWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFDIKPENVMC 351
V E + GG L D+ + SER+ L + ++Y+H G++H D+KP N++
Sbjct: 474 YVYVVTELMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQGVVHRDLKPSNILY 533
Query: 352 C--SLNCLNIKIIDFGLTKCARSRTPINRNFGFFSS-VAPELYSGNVLTTAYDMWSVGIL 408
S N +I+I DFG K R+ + + ++ VAPE+ A D+WS+G+L
Sbjct: 534 VDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDAACDIWSLGVL 593
Query: 409 MGIGLLGYTPRIIGKRSRRLSVV---------FTSQEYLCISGAALHFFGKCLHTNPSRR 459
+ L GYTP G ++ + + +S A K LH +P +R
Sbjct: 594 LYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWNSVSDTAKDLVSKMLHVDPHQR 653
Query: 460 LTAAQALNHPWM 471
LTAA L HPW+
Sbjct: 654 LTAALVLRHPWI 665
Score = 92.7 bits (220), Expect = 4e-18
Identities = 69/245 (28%), Positives = 117/245 (47%), Gaps = 13/245 (5%)
Query: 229 LKLIGSGVYGKVMLIRSNAG---KQFVAKTVISQYQTNSMEEYST-----LRILRNTPNI 280
LK++G G +GKV L++ +G +Q A V+ + + T + + N P I
Sbjct: 57 LKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKMERDILVEVNHPFI 116
Query: 281 VKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLI 340
VKL + +++ L GG+LF R +E D+K YL ++ L ++H+ G+I
Sbjct: 117 VKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLGII 176
Query: 341 HFDIKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNF-GFFSSVAPELYSGNVLTTA 399
+ D+KPEN++ +IK+ DFGL+K + +F G +APE+ + T +
Sbjct: 177 YRDLKPENILLDEEG--HIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVVNRRGHTQS 234
Query: 400 YDMWSVGILMGIGLLGYTPRIIGKRSRRLSVVFTSQEYL--CISGAALHFFGKCLHTNPS 457
D WS G+LM L G P R ++++ ++ + +S A NP+
Sbjct: 235 ADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEAQSLLRMLFKRNPA 294
Query: 458 RRLTA 462
RL A
Sbjct: 295 NRLGA 299
>AB046859-1|BAB13465.2| 2584|Homo sapiens KIAA1639 protein protein.
Length = 2584
Score = 110 bits (264), Expect = 2e-23
Identities = 78/282 (27%), Positives = 134/282 (47%), Gaps = 19/282 (6%)
Query: 207 EPLITSPQYLKSLQNFYRDFLPLKLIGSGVYGKVMLIRSNAGKQFVAKTVISQYQTNSME 266
EP + + L +FY + IG GV+G V ++ K A I +
Sbjct: 1068 EPDSEKQSHRRKLHSFYE---VKEEIGRGVFGFVKRVQHKGNKILCAAKFIPLRSRTRAQ 1124
Query: 267 EYSTLRILR--NTPNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYL 324
Y IL + P + L++ + + ++E L DR ++E ++K+Y+
Sbjct: 1125 AYRERDILAALSHPLVTGLLDQFETRKTLILILELCSSEELLDRLYRKGVVTEAEVKVYI 1184
Query: 325 RQVCSGLQYIHNNGLIHFDIKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNFGFFS 384
+Q+ GL Y+H++G++H DIKP N++ +IKI DFG A++ TP F +
Sbjct: 1185 QQLVEGLHYLHSHGVLHLDIKPSNILMVHPAREDIKICDFGF---AQNITPAELQFSQYG 1241
Query: 385 S---VAPELYSGNVLTTAYDMWSVGILMGIGLLGYTPRIIGK--RSRRLSVV-----FTS 434
S V+PE+ N ++ A D+W++G++ + L +P G+ R+ L+V+ ++S
Sbjct: 1242 SPEFVSPEIIQQNPVSEASDIWAMGVISYLSLTCSSP-FAGESDRATLLNVLEGRVSWSS 1300
Query: 435 QEYLCISGAALHFFGKCLHTNPSRRLTAAQALNHPWMFDTCP 476
+S A F L P R +AAQ L+HPW + P
Sbjct: 1301 PMAAHLSEDAKDFIKATLQRAPQARPSAAQCLSHPWFLKSMP 1342
Score = 90.2 bits (214), Expect = 2e-17
Identities = 63/223 (28%), Positives = 103/223 (46%), Gaps = 10/223 (4%)
Query: 261 QTNSMEEYSTLRILRNTPNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDI 320
+T + EY L+ LR+ P++ +L Y + V ++E G L SE ++
Sbjct: 2326 KTAVLREYEALKGLRH-PHLAQLHAAYLSPRHLVLILELCSGPELLPCLAERASYSESEV 2384
Query: 321 KIYLRQVCSGLQYIHNNGLIHFDIKPENVMCCSLNCLNIKIIDFGLTKCARSR--TPINR 378
K YL Q+ S QY+HN ++H D++ EN++ N L K++D G + P ++
Sbjct: 2385 KDYLWQMLSATQYLHNQHILHLDLRSENMIITEYNLL--KVVDLGNAQSLSQEKVLPSDK 2442
Query: 379 NFGFFSSVAPELYSGNVLTTAYDMWSVGILMGIGLLG-YTPRIIG----KRSRRLSVVFT 433
+ ++APEL G D+W++G+ I L Y G +R R +V
Sbjct: 2443 FKDYLETMAPELLEGQGAVPQTDIWAIGVTAFIMLSAEYPVSSEGARDLQRGLRKGLVRL 2502
Query: 434 SQEYLCISGAALHFFGKCLHTNPSRRLTAAQALNHPWMFDTCP 476
S+ Y +SG A+ F L P R A+ L PW+ + P
Sbjct: 2503 SRCYAGLSGGAVAFLRSTLCAQPWGRPCASSCLQCPWLTEEGP 2545
>AF069604-1|AAD15924.1| 560|Homo sapiens myosin light chain kinase
isoform 4 protein.
Length = 560
Score = 109 bits (262), Expect = 3e-23
Identities = 67/202 (33%), Positives = 105/202 (51%), Gaps = 10/202 (4%)
Query: 303 GNLFDRFKHHQC-ISERDIKIYLRQVCSGLQYIHNNGLIHFDIKPENVMCCSLNCLNIKI 361
G+LF+R ++ER+ Y+RQ+ G++YIH G++H D+KPEN+MC + IK+
Sbjct: 191 GSLFERIIDEDFELTERECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKL 250
Query: 362 IDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLTTAYDMWSVGILMGIGLLGYTPRII 421
IDFGL + + + FG VAPE+ + + A DMWS+G++ I + G +P +
Sbjct: 251 IDFGLARRLENAGSLKVLFGTPEFVAPEVINYEPI-DATDMWSIGVICYILVSGLSPFMG 309
Query: 422 GKRSRRLSVV------FTSQEYLCISGAALHFFGKCLHTNPSRRLTAAQALNHPWMFDTC 475
+ L+ V F + + IS A F L + RL Q L HPW+
Sbjct: 310 DNDNETLANVTSATWDFDDEAFDEISDDAKDFISNLLKKDMKNRLDCTQCLQHPWLMKDT 369
Query: 476 PHPLSWKKPSKNRRYNRYMGQR 497
+ + KK SK+ R +YM +R
Sbjct: 370 KN-MEAKKLSKD-RMKKYMARR 389
>AF069603-1|AAD15923.1| 1793|Homo sapiens myosin light chain kinase
isoform 3B protein.
Length = 1793
Score = 109 bits (262), Expect = 3e-23
Identities = 59/182 (32%), Positives = 102/182 (56%), Gaps = 7/182 (3%)
Query: 232 IGSGVYGKVM-LIRSNAGKQFVAK---TVISQYQTNSMEEYSTLRILRNTPNIVKLIECY 287
+GSG +G+V L+ K + K ++ + N +E + + L + P +V+ ++ +
Sbjct: 1401 LGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEITIMNCLHH-PKLVQCVDAF 1459
Query: 288 SDGLNWVFVMENLWGGNLFDRFKHHQC-ISERDIKIYLRQVCSGLQYIHNNGLIHFDIKP 346
+ N V V+E + GG LF+R ++ER+ Y+RQ+ G++YIH G++H D+KP
Sbjct: 1460 EEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYIHKQGIVHLDLKP 1519
Query: 347 ENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLTTAYDMWSVG 406
EN+MC + IK+IDFGL + + + FG VAPE+ + + A DMWS+G
Sbjct: 1520 ENIMCVNKTGTRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVINYEPI-DATDMWSIG 1578
Query: 407 IL 408
++
Sbjct: 1579 VI 1580
>AF069602-1|AAD15922.1| 1862|Homo sapiens myosin light chain kinase
isoform 3A protein.
Length = 1862
Score = 109 bits (262), Expect = 3e-23
Identities = 59/182 (32%), Positives = 102/182 (56%), Gaps = 7/182 (3%)
Query: 232 IGSGVYGKVM-LIRSNAGKQFVAK---TVISQYQTNSMEEYSTLRILRNTPNIVKLIECY 287
+GSG +G+V L+ K + K ++ + N +E + + L + P +V+ ++ +
Sbjct: 1470 LGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEITIMNCLHH-PKLVQCVDAF 1528
Query: 288 SDGLNWVFVMENLWGGNLFDRFKHHQC-ISERDIKIYLRQVCSGLQYIHNNGLIHFDIKP 346
+ N V V+E + GG LF+R ++ER+ Y+RQ+ G++YIH G++H D+KP
Sbjct: 1529 EEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYIHKQGIVHLDLKP 1588
Query: 347 ENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLTTAYDMWSVG 406
EN+MC + IK+IDFGL + + + FG VAPE+ + + A DMWS+G
Sbjct: 1589 ENIMCVNKTGTRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVINYEPI-DATDMWSIG 1647
Query: 407 IL 408
++
Sbjct: 1648 VI 1649
>AF080000-1|AAD23915.1| 802|Homo sapiens RSK-like protein kinase
RLPK protein.
Length = 802
Score = 109 bits (261), Expect = 4e-23
Identities = 58/178 (32%), Positives = 95/178 (53%), Gaps = 2/178 (1%)
Query: 243 IRSNAGKQFVAKTVISQYQTNSMEEYSTLRILRNTPNIVKLIECYSDGLNWVFVMENLWG 302
+ + + F K + + + N+ +E + L++ PNIVKL E + D L+ VME L G
Sbjct: 444 VHKKSNQAFAVKIISKRMEANTQKEITALKLCEGHPNIVKLHEVFHDQLHTFLVMELLNG 503
Query: 303 GNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFDIKPENVMCCSLN-CLNIKI 361
G LF+R K + SE + +R++ S + ++H+ G++H D+KPEN++ N L IKI
Sbjct: 504 GELFERIKKKKHFSETEASYIMRKLVSAVSHMHDVGVVHRDLKPENLLFTDENDNLEIKI 563
Query: 362 IDFGLTKC-ARSRTPINRNFGFFSSVAPELYSGNVLTTAYDMWSVGILMGIGLLGYTP 418
IDFG + P+ APEL + N + D+WS+G+++ L G P
Sbjct: 564 IDFGFARLKPPDNQPLKTPCFTLHYAAPELLNQNGYDESCDLWSLGVILYTMLSGQVP 621
Score = 85.4 bits (202), Expect = 6e-16
Identities = 60/209 (28%), Positives = 108/209 (51%), Gaps = 17/209 (8%)
Query: 225 DFLPLKLIGSGVYGKVMLIRS----NAGKQFVAK-----TVISQYQT--NSMEEYSTLRI 273
+F LK++G+G YGKV L+R + GK + K T++ + +T ++ E L
Sbjct: 48 NFELLKVLGTGAYGKVFLVRKISGHDTGKLYAMKVLKKATIVQKAKTTEHTRTERQVLEH 107
Query: 274 LRNTPNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQY 333
+R +P +V L + +++ + GG LF + +E +++IY+ ++ L++
Sbjct: 108 IRQSPFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIVLALEH 167
Query: 334 IHNNGLIHFDIKPENVMCCSLNCLNIKIIDFGLTK-CARSRTPINRNF-GFFSSVAPELY 391
+H G+I+ DIK EN++ S ++ + DFGL+K T +F G +AP++
Sbjct: 168 LHKLGIIYRDIKLENILLDSNG--HVVLTDFGLSKEFVADETERAYSFCGTIEYMAPDIV 225
Query: 392 SG--NVLTTAYDMWSVGILMGIGLLGYTP 418
G + A D WS+G+LM L G +P
Sbjct: 226 RGGDSGHDKAVDWWSLGVLMYELLTGASP 254
>AF074393-1|AAC31171.1| 802|Homo sapiens nuclear mitogen- and
stress-activated protein kinase-1 protein.
Length = 802
Score = 109 bits (261), Expect = 4e-23
Identities = 58/178 (32%), Positives = 95/178 (53%), Gaps = 2/178 (1%)
Query: 243 IRSNAGKQFVAKTVISQYQTNSMEEYSTLRILRNTPNIVKLIECYSDGLNWVFVMENLWG 302
+ + + F K + + + N+ +E + L++ PNIVKL E + D L+ VME L G
Sbjct: 444 VHKKSNQAFAVKIISKRMEANTQKEITALKLCEGHPNIVKLHEVFHDQLHTFLVMELLNG 503
Query: 303 GNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFDIKPENVMCCSLN-CLNIKI 361
G LF+R K + SE + +R++ S + ++H+ G++H D+KPEN++ N L IKI
Sbjct: 504 GELFERIKKKKHFSETEASYIMRKLVSAVSHMHDVGVVHRDLKPENLLFTDENDNLEIKI 563
Query: 362 IDFGLTKC-ARSRTPINRNFGFFSSVAPELYSGNVLTTAYDMWSVGILMGIGLLGYTP 418
IDFG + P+ APEL + N + D+WS+G+++ L G P
Sbjct: 564 IDFGFARLKPPDNQPLKTPCFTLHYAAPELLNQNGYDESCDLWSLGVILYTMLSGQVP 621
Score = 85.4 bits (202), Expect = 6e-16
Identities = 60/209 (28%), Positives = 108/209 (51%), Gaps = 17/209 (8%)
Query: 225 DFLPLKLIGSGVYGKVMLIRS----NAGKQFVAK-----TVISQYQT--NSMEEYSTLRI 273
+F LK++G+G YGKV L+R + GK + K T++ + +T ++ E L
Sbjct: 48 NFELLKVLGTGAYGKVFLVRKISGHDTGKLYAMKVLKKATIVQKAKTTEHTRTERQVLEH 107
Query: 274 LRNTPNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQY 333
+R +P +V L + +++ + GG LF + +E +++IY+ ++ L++
Sbjct: 108 IRQSPFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIVLALEH 167
Query: 334 IHNNGLIHFDIKPENVMCCSLNCLNIKIIDFGLTK-CARSRTPINRNF-GFFSSVAPELY 391
+H G+I+ DIK EN++ S ++ + DFGL+K T +F G +AP++
Sbjct: 168 LHKLGIIYRDIKLENILLDSNG--HVVLTDFGLSKEFVADETERAYSFCGTIEYMAPDIV 225
Query: 392 SG--NVLTTAYDMWSVGILMGIGLLGYTP 418
G + A D WS+G+LM L G +P
Sbjct: 226 RGGDSGHDKAVDWWSLGVLMYELLTGASP 254
>AM231061-1|CAJ76912.1| 1960|Homo sapiens obscurin isoform B
protein.
Length = 1960
Score = 108 bits (259), Expect = 8e-23
Identities = 77/282 (27%), Positives = 133/282 (47%), Gaps = 19/282 (6%)
Query: 207 EPLITSPQYLKSLQNFYRDFLPLKLIGSGVYGKVMLIRSNAGKQFVAKTVISQYQTNSME 266
EP + + L +FY + IG GV+G V ++ K A I +
Sbjct: 444 EPDSEKQSHRRKLHSFYE---VKEEIGRGVFGFVKRVQHKGNKILCAAKFIPLRSRTRAQ 500
Query: 267 EYSTLRILR--NTPNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYL 324
Y IL + P + L++ + + ++E L DR ++E ++K+Y+
Sbjct: 501 AYRERDILAALSHPLVTGLLDQFETRKTLILILELCSSEELLDRLYRKGVVTEAEVKVYI 560
Query: 325 RQVCSGLQYIHNNGLIHFDIKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNFGFFS 384
+++ GL Y+H++G++H DIKP N++ +IKI DFG A++ TP F +
Sbjct: 561 QELVEGLHYLHSHGVLHLDIKPSNILMVHPAREDIKICDFGF---AQNITPAELQFSQYG 617
Query: 385 S---VAPELYSGNVLTTAYDMWSVGILMGIGLLGYTPRIIGK--RSRRLSVV-----FTS 434
S V+PE+ N ++ A D+W++G++ + L +P G+ R+ L+V+ ++S
Sbjct: 618 SPEFVSPEIIQQNPVSEASDIWAMGVISYLSLTCSSP-FAGESDRATLLNVLEGRVSWSS 676
Query: 435 QEYLCISGAALHFFGKCLHTNPSRRLTAAQALNHPWMFDTCP 476
+S A F L P R AAQ L+HPW + P
Sbjct: 677 PMAAHLSEDAKDFIKATLQRAPQARSGAAQCLSHPWFLKSMP 718
Score = 90.2 bits (214), Expect = 2e-17
Identities = 63/223 (28%), Positives = 103/223 (46%), Gaps = 10/223 (4%)
Query: 261 QTNSMEEYSTLRILRNTPNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDI 320
+T + EY L+ LR+ P++ +L Y + V ++E G L SE ++
Sbjct: 1702 KTAVLREYEALKGLRH-PHLAQLHAAYLSPRHLVLILELCSGPELLPCLAERASYSESEV 1760
Query: 321 KIYLRQVCSGLQYIHNNGLIHFDIKPENVMCCSLNCLNIKIIDFGLTKCARSR--TPINR 378
K YL Q+ S QY+HN ++H D++ EN++ N L K++D G + P ++
Sbjct: 1761 KDYLWQMLSATQYLHNQHILHLDLRSENMIITEYNLL--KVVDLGNAQSLSQEKVLPSDK 1818
Query: 379 NFGFFSSVAPELYSGNVLTTAYDMWSVGILMGIGLLG-YTPRIIG----KRSRRLSVVFT 433
+ ++APEL G D+W++G+ I L Y G +R R +V
Sbjct: 1819 FKDYLETMAPELLEGQGAVPQTDIWAIGVTAFIMLSAEYPVSSEGARDLQRGLRKGLVRL 1878
Query: 434 SQEYLCISGAALHFFGKCLHTNPSRRLTAAQALNHPWMFDTCP 476
S+ Y +SG A+ F L P R A+ L PW+ + P
Sbjct: 1879 SRCYAGLSGGAVAFLRSTLCAQPWGRPCASSCLQCPWLTEEGP 1921
>BC040457-1|AAH40457.1| 478|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II alpha protein.
Length = 478
Score = 105 bits (253), Expect = 4e-22
Identities = 71/263 (26%), Positives = 128/263 (48%), Gaps = 13/263 (4%)
Query: 222 FYRDFLPLKLIGSGVYGKVM-LIRSNAGKQFVAKTV----ISQYQTNSMEEYSTLRILRN 276
F ++ + +G G + V ++ AG+++ AK + +S +E + + L
Sbjct: 9 FTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLK 68
Query: 277 TPNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHN 336
PNIV+L + S+ + + + + GG LF+ + SE D ++Q+ + + H
Sbjct: 69 HPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQ 128
Query: 337 NGLIHFDIKPENVMCCS-LNCLNIKIIDFGLTKCARSRTPINRNF-GFFSSVAPELYSGN 394
G++H D+KPEN++ S L +K+ DFGL F G ++PE+ +
Sbjct: 129 MGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRKD 188
Query: 395 VLTTAYDMWSVGILMGIGLLGYTP------RIIGKRSRRLSVVFTSQEYLCISGAALHFF 448
D+W+ G+++ I L+GY P + K+ + + F S E+ ++ A
Sbjct: 189 PYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYKQIKAGAYDFPSPEWDTVTPEAKDLI 248
Query: 449 GKCLHTNPSRRLTAAQALNHPWM 471
K L NPS+R+TAA+AL HPW+
Sbjct: 249 NKMLTINPSKRITAAEALKHPWI 271
>AF090421-1|AAC69577.1| 809|Homo sapiens ribosome S6 protein kinase
protein.
Length = 809
Score = 105 bits (251), Expect = 7e-22
Identities = 57/178 (32%), Positives = 93/178 (52%), Gaps = 2/178 (1%)
Query: 243 IRSNAGKQFVAKTVISQYQTNSMEEYSTLRILRNTPNIVKLIECYSDGLNWVFVMENLWG 302
+ + + K + + + N+ +E + L++ PNIVKL E + D L+ VME L G
Sbjct: 444 VHKKSNQALQVKIISKRMEANTQKEITALKLCEGHPNIVKLHEVFHDQLHTFLVMELLNG 503
Query: 303 GNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFDIKPENVMCCSLN-CLNIKI 361
G LFD + + SE + +R++ S L ++H+ G++H D+KPEN++ N L IKI
Sbjct: 504 GELFDALRKKKHFSETEASYIMRKLVSALSHMHDLGVVHRDLKPENLLFTDENDNLEIKI 563
Query: 362 IDFGLTKC-ARSRTPINRNFGFFSSVAPELYSGNVLTTAYDMWSVGILMGIGLLGYTP 418
IDFG + P+ S PEL + N + D+WS+G+++ L G P
Sbjct: 564 IDFGFARLKPPDNQPLKTPCFTLHSCRPELLNQNGYDESCDLWSLGVILYTMLSGQVP 621
Score = 85.4 bits (202), Expect = 6e-16
Identities = 60/209 (28%), Positives = 108/209 (51%), Gaps = 17/209 (8%)
Query: 225 DFLPLKLIGSGVYGKVMLIRS----NAGKQFVAK-----TVISQYQT--NSMEEYSTLRI 273
+F LK++G+G YGKV L+R + GK + K T++ + +T ++ E L
Sbjct: 48 NFELLKVLGTGAYGKVFLVRKISGHDTGKLYAMKVLKKATIVQKAKTTEHTRTERQVLEH 107
Query: 274 LRNTPNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQY 333
+R +P +V L + +++ + GG LF + +E +++IY+ ++ L++
Sbjct: 108 IRQSPFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIVLALEH 167
Query: 334 IHNNGLIHFDIKPENVMCCSLNCLNIKIIDFGLTK-CARSRTPINRNF-GFFSSVAPELY 391
+H G+I+ DIK EN++ S ++ + DFGL+K T +F G +AP++
Sbjct: 168 LHKLGIIYRDIKLENILLDSNG--HVVLTDFGLSKEFVADETERAYSFCGTIEYMAPDIV 225
Query: 392 SG--NVLTTAYDMWSVGILMGIGLLGYTP 418
G + A D WS+G+LM L G +P
Sbjct: 226 RGGDSGHDKAVDWWSLGVLMYELLTGASP 254
>AF145711-1|AAD30559.1| 489|Homo sapiens
calcium/calmodulin-dependent protein kinase II alpha-B
subunit protein.
Length = 489
Score = 104 bits (250), Expect = 1e-21
Identities = 71/263 (26%), Positives = 126/263 (47%), Gaps = 13/263 (4%)
Query: 222 FYRDFLPLKLIGSGVYGKVM-LIRSNAGKQFVAKTV----ISQYQTNSMEEYSTLRILRN 276
F ++ + +G G + V ++ AG+++ AK + +S +E + + L
Sbjct: 9 FTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLK 68
Query: 277 TPNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHN 336
PNIV+L + S+ + + + + GG LF+ + SE D ++Q+ + + H
Sbjct: 69 HPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQ 128
Query: 337 NGLIHFDIKPENVMCCS-LNCLNIKIIDFGLTKCARSRTPINRNF-GFFSSVAPELYSGN 394
G++H D+KPEN++ S L +K+ DFGL F G ++PE+ +
Sbjct: 129 MGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRKD 188
Query: 395 VLTTAYDMWSVGILMGIGLLGYTPRIIGKRSRRLSVV------FTSQEYLCISGAALHFF 448
D+W+ G+++ I L+GY P + R + F S E+ ++ A
Sbjct: 189 PYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLI 248
Query: 449 GKCLHTNPSRRLTAAQALNHPWM 471
K L NPS+R+TAA+AL HPW+
Sbjct: 249 NKMLTINPSKRITAAEALKHPWI 271
>AF145710-1|AAD30558.1| 478|Homo sapiens
calcium/calmodulin-dependent protein kinase II alpha
subunit protein.
Length = 478
Score = 104 bits (250), Expect = 1e-21
Identities = 71/263 (26%), Positives = 126/263 (47%), Gaps = 13/263 (4%)
Query: 222 FYRDFLPLKLIGSGVYGKVM-LIRSNAGKQFVAKTV----ISQYQTNSMEEYSTLRILRN 276
F ++ + +G G + V ++ AG+++ AK + +S +E + + L
Sbjct: 9 FTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLK 68
Query: 277 TPNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHN 336
PNIV+L + S+ + + + + GG LF+ + SE D ++Q+ + + H
Sbjct: 69 HPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQ 128
Query: 337 NGLIHFDIKPENVMCCS-LNCLNIKIIDFGLTKCARSRTPINRNF-GFFSSVAPELYSGN 394
G++H D+KPEN++ S L +K+ DFGL F G ++PE+ +
Sbjct: 129 MGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRKD 188
Query: 395 VLTTAYDMWSVGILMGIGLLGYTPRIIGKRSRRLSVV------FTSQEYLCISGAALHFF 448
D+W+ G+++ I L+GY P + R + F S E+ ++ A
Sbjct: 189 PYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLI 248
Query: 449 GKCLHTNPSRRLTAAQALNHPWM 471
K L NPS+R+TAA+AL HPW+
Sbjct: 249 NKMLTINPSKRITAAEALKHPWI 271
>AF091486-1|AAD55815.1| 478|Homo sapiens calmodulin-dependent
protein kinase II alpha protein.
Length = 478
Score = 104 bits (250), Expect = 1e-21
Identities = 71/263 (26%), Positives = 126/263 (47%), Gaps = 13/263 (4%)
Query: 222 FYRDFLPLKLIGSGVYGKVM-LIRSNAGKQFVAKTV----ISQYQTNSMEEYSTLRILRN 276
F ++ + +G G + V ++ AG+++ AK + +S +E + + L
Sbjct: 9 FTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLK 68
Query: 277 TPNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHN 336
PNIV+L + S+ + + + + GG LF+ + SE D ++Q+ + + H
Sbjct: 69 HPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQ 128
Query: 337 NGLIHFDIKPENVMCCS-LNCLNIKIIDFGLTKCARSRTPINRNF-GFFSSVAPELYSGN 394
G++H D+KPEN++ S L +K+ DFGL F G ++PE+ +
Sbjct: 129 MGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRKD 188
Query: 395 VLTTAYDMWSVGILMGIGLLGYTPRIIGKRSRRLSVV------FTSQEYLCISGAALHFF 448
D+W+ G+++ I L+GY P + R + F S E+ ++ A
Sbjct: 189 PYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLI 248
Query: 449 GKCLHTNPSRRLTAAQALNHPWM 471
K L NPS+R+TAA+AL HPW+
Sbjct: 249 NKMLTINPSKRITAAEALKHPWI 271
>AB023185-1|BAA76812.1| 527|Homo sapiens KIAA0968 protein protein.
Length = 527
Score = 104 bits (250), Expect = 1e-21
Identities = 71/263 (26%), Positives = 126/263 (47%), Gaps = 13/263 (4%)
Query: 222 FYRDFLPLKLIGSGVYGKVM-LIRSNAGKQFVAKTV----ISQYQTNSMEEYSTLRILRN 276
F ++ + +G G + V ++ AG+++ AK + +S +E + + L
Sbjct: 58 FTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLLK 117
Query: 277 TPNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHN 336
PNIV+L + S+ + + + + GG LF+ + SE D ++Q+ + + H
Sbjct: 118 HPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQ 177
Query: 337 NGLIHFDIKPENVMCCS-LNCLNIKIIDFGLTKCARSRTPINRNF-GFFSSVAPELYSGN 394
G++H D+KPEN++ S L +K+ DFGL F G ++PE+ +
Sbjct: 178 MGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYLSPEVLRKD 237
Query: 395 VLTTAYDMWSVGILMGIGLLGYTPRIIGKRSRRLSVV------FTSQEYLCISGAALHFF 448
D+W+ G+++ I L+GY P + R + F S E+ ++ A
Sbjct: 238 PYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLI 297
Query: 449 GKCLHTNPSRRLTAAQALNHPWM 471
K L NPS+R+TAA+AL HPW+
Sbjct: 298 NKMLTINPSKRITAAEALKHPWI 320
>AB011422-1|BAA76314.1| 1289|Homo sapiens Trad protein.
Length = 1289
Score = 104 bits (250), Expect = 1e-21
Identities = 75/274 (27%), Positives = 122/274 (44%), Gaps = 14/274 (5%)
Query: 220 QNFYRDFLPLKLIGSGVYGKVMLIRSNAGKQFVAKTVISQYQTNSMEEYSTLRILRNT-- 277
+NF + L IG G + V A ++ VA +S+ + +L++
Sbjct: 981 ENFDSAYTELNEIGRGRFSIVKKCIHKATRKDVAVKFVSKKMKKKEQAAHEAALLQHLQH 1040
Query: 278 PNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNN 337
P + L + Y +++ ++E + G L D +H + E + Y+R + LQY+HN
Sbjct: 1041 PQYITLHDTYESPTSYILILELMDDGRLLDYLMNHDELMEEKVAFYIRDIMEALQYLHNC 1100
Query: 338 GLIHFDIKPENVMC-CSLNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVL 396
+ H DIKPEN++ + +K+ID I+ G APE+ G +
Sbjct: 1101 RVAHLDIKPENLLIDLRIPVPRVKLIDLEDAVQISGHFHIHHLLGNPEFAAPEVIQGIPV 1160
Query: 397 TTAYDMWSVGILMGIGLLGYTPRIIGKRSR------RLSVVFTSQEYLC-ISGAALHFFG 449
+ D+WS+G+L + L G +P + + R+ F EY C +S AA F
Sbjct: 1161 SLGTDIWSIGVLTYVMLSGVSPFLDESKEETCINVCRVDFSF-PHEYFCGVSNAARDFIN 1219
Query: 450 KCLHTNPSRRLTAAQALNHPWMFDTCPHPLSWKK 483
L + RR TAA L HPW+ PH S+ K
Sbjct: 1220 VILQEDFRRRPTAATCLQHPWL---QPHNGSYSK 1250
>CR536566-1|CAG38803.1| 745|Homo sapiens RPS6KA6 protein.
Length = 745
Score = 103 bits (248), Expect = 2e-21
Identities = 73/253 (28%), Positives = 112/253 (44%), Gaps = 14/253 (5%)
Query: 232 IGSGVYGKVM-LIRSNAGKQFVAKTVISQYQTNSMEEYSTLRILRNTPNIVKLIECYSDG 290
IG G Y I + +F K +I + + + EE L PNI+ L + + DG
Sbjct: 432 IGVGSYSVCKRCIHATTNMEFAVK-IIDKSKRDPSEEIEILMRYGQHPNIITLKDVFDDG 490
Query: 291 LNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFDIKPENVM 350
V + + GG L DR +C SER+ L + + Y+H G++H D+KP N++
Sbjct: 491 RYVYLVTDLMKGGELLDRILKQKCFSEREASDILYVISKTVDYLHCQGVVHRDLKPSNIL 550
Query: 351 CC--SLNCLNIKIIDFGLTKCARSRTPINRNFGFFSS-VAPELYSGNVLTTAYDMWSVGI 407
S + +I+I DFG K R + + ++ VAPE+ A D+WS+G+
Sbjct: 551 YMDESASADSIRICDFGFAKQLRGENGLLLTPCYTANFVAPEVLMQQGYDAACDIWSLGV 610
Query: 408 LMGIGLLGYTPRIIGKRSRRLSVV---------FTSQEYLCISGAALHFFGKCLHTNPSR 458
L L GYTP G ++ + + IS A LH +P +
Sbjct: 611 LFYTMLAGYTPFANGPNDTPEEILLRIGNGKFSLSGGNWDNISDGAKDLLSHMLHMDPHQ 670
Query: 459 RLTAAQALNHPWM 471
R TA Q L H W+
Sbjct: 671 RYTAEQILKHSWI 683
Score = 91.9 bits (218), Expect = 7e-18
Identities = 66/243 (27%), Positives = 115/243 (47%), Gaps = 13/243 (5%)
Query: 229 LKLIGSGVYGKVMLIRSNAGK---QFVAKTVISQYQTNSMEEYST-----LRILRNTPNI 280
LK++G G +GKV L+R G Q A V+ + T + + N P I
Sbjct: 76 LKVLGQGSFGKVFLVRKKTGPDAGQLYAMKVLKKASLKVRGRVRTKMERDILVEVNHPFI 135
Query: 281 VKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLI 340
VKL + +++ L GG++F R +E D+K YL ++ L ++H G++
Sbjct: 136 VKLHYAFQTEGKLYLILDFLRGGDVFTRLSKEVLFTEEDVKFYLAELALALDHLHQLGIV 195
Query: 341 HFDIKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNF-GFFSSVAPELYSGNVLTTA 399
+ D+KPEN++ + +IK+ DFGL+K + + +F G +APE+ + + +
Sbjct: 196 YRDLKPENILLDEIG--HIKLTDFGLSKESVDQEKKAYSFCGTVEYMAPEVVNRRGHSQS 253
Query: 400 YDMWSVGILMGIGLLGYTPRIIGKRSRRLSVVFTSQEYL--CISGAALHFFGKCLHTNPS 457
D WS G+LM L G P R+ ++++ ++ + +S A NP+
Sbjct: 254 ADWWSYGVLMFEMLTGTLPFQGKDRNETMNMILKAKLGMPQLLSAEAQSLLRMLFKRNPA 313
Query: 458 RRL 460
RL
Sbjct: 314 NRL 316
>AL389887-1|CAC16111.2| 745|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 6 protein.
Length = 745
Score = 103 bits (248), Expect = 2e-21
Identities = 73/253 (28%), Positives = 112/253 (44%), Gaps = 14/253 (5%)
Query: 232 IGSGVYGKVM-LIRSNAGKQFVAKTVISQYQTNSMEEYSTLRILRNTPNIVKLIECYSDG 290
IG G Y I + +F K +I + + + EE L PNI+ L + + DG
Sbjct: 432 IGVGSYSVCKRCIHATTNMEFAVK-IIDKSKRDPSEEIEILMRYGQHPNIITLKDVFDDG 490
Query: 291 LNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFDIKPENVM 350
V + + GG L DR +C SER+ L + + Y+H G++H D+KP N++
Sbjct: 491 RYVYLVTDLMKGGELLDRILKQKCFSEREASDILYVISKTVDYLHCQGVVHRDLKPSNIL 550
Query: 351 CC--SLNCLNIKIIDFGLTKCARSRTPINRNFGFFSS-VAPELYSGNVLTTAYDMWSVGI 407
S + +I+I DFG K R + + ++ VAPE+ A D+WS+G+
Sbjct: 551 YMDESASADSIRICDFGFAKQLRGENGLLLTPCYTANFVAPEVLMQQGYDAACDIWSLGV 610
Query: 408 LMGIGLLGYTPRIIGKRSRRLSVV---------FTSQEYLCISGAALHFFGKCLHTNPSR 458
L L GYTP G ++ + + IS A LH +P +
Sbjct: 611 LFYTMLAGYTPFANGPNDTPEEILLRIGNGKFSLSGGNWDNISDGAKDLLSHMLHMDPHQ 670
Query: 459 RLTAAQALNHPWM 471
R TA Q L H W+
Sbjct: 671 RYTAEQILKHSWI 683
Score = 93.1 bits (221), Expect = 3e-18
Identities = 66/243 (27%), Positives = 116/243 (47%), Gaps = 13/243 (5%)
Query: 229 LKLIGSGVYGKVMLIRSNAGK---QFVAKTVISQYQTNSMEEYST-----LRILRNTPNI 280
LK++G G +GKV L+R G Q A V+ + + T + + N P I
Sbjct: 76 LKVLGQGSFGKVFLVRKKTGPDAGQLYAMKVLKKASLKVRDRVRTKMERDILVEVNHPFI 135
Query: 281 VKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLI 340
VKL + +++ L GG++F R +E D+K YL ++ L ++H G++
Sbjct: 136 VKLHYAFQTEGKLYLILDFLRGGDVFTRLSKEVLFTEEDVKFYLAELALALDHLHQLGIV 195
Query: 341 HFDIKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNF-GFFSSVAPELYSGNVLTTA 399
+ D+KPEN++ + +IK+ DFGL+K + + +F G +APE+ + + +
Sbjct: 196 YRDLKPENILLDEIG--HIKLTDFGLSKESVDQEKKAYSFCGTVEYMAPEVVNRRGHSQS 253
Query: 400 YDMWSVGILMGIGLLGYTPRIIGKRSRRLSVVFTSQEYL--CISGAALHFFGKCLHTNPS 457
D WS G+LM L G P R+ ++++ ++ + +S A NP+
Sbjct: 254 ADWWSYGVLMFEMLTGTLPFQGKDRNETMNMILKAKLGMPQFLSAEAQSLLRMLFKRNPA 313
Query: 458 RRL 460
RL
Sbjct: 314 NRL 316
>AL354653-1|CAD13486.2| 745|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 6 protein.
Length = 745
Score = 103 bits (248), Expect = 2e-21
Identities = 73/253 (28%), Positives = 112/253 (44%), Gaps = 14/253 (5%)
Query: 232 IGSGVYGKVM-LIRSNAGKQFVAKTVISQYQTNSMEEYSTLRILRNTPNIVKLIECYSDG 290
IG G Y I + +F K +I + + + EE L PNI+ L + + DG
Sbjct: 432 IGVGSYSVCKRCIHATTNMEFAVK-IIDKSKRDPSEEIEILMRYGQHPNIITLKDVFDDG 490
Query: 291 LNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFDIKPENVM 350
V + + GG L DR +C SER+ L + + Y+H G++H D+KP N++
Sbjct: 491 RYVYLVTDLMKGGELLDRILKQKCFSEREASDILYVISKTVDYLHCQGVVHRDLKPSNIL 550
Query: 351 CC--SLNCLNIKIIDFGLTKCARSRTPINRNFGFFSS-VAPELYSGNVLTTAYDMWSVGI 407
S + +I+I DFG K R + + ++ VAPE+ A D+WS+G+
Sbjct: 551 YMDESASADSIRICDFGFAKQLRGENGLLLTPCYTANFVAPEVLMQQGYDAACDIWSLGV 610
Query: 408 LMGIGLLGYTPRIIGKRSRRLSVV---------FTSQEYLCISGAALHFFGKCLHTNPSR 458
L L GYTP G ++ + + IS A LH +P +
Sbjct: 611 LFYTMLAGYTPFANGPNDTPEEILLRIGNGKFSLSGGNWDNISDGAKDLLSHMLHMDPHQ 670
Query: 459 RLTAAQALNHPWM 471
R TA Q L H W+
Sbjct: 671 RYTAEQILKHSWI 683
Score = 93.1 bits (221), Expect = 3e-18
Identities = 66/243 (27%), Positives = 116/243 (47%), Gaps = 13/243 (5%)
Query: 229 LKLIGSGVYGKVMLIRSNAGK---QFVAKTVISQYQTNSMEEYST-----LRILRNTPNI 280
LK++G G +GKV L+R G Q A V+ + + T + + N P I
Sbjct: 76 LKVLGQGSFGKVFLVRKKTGPDAGQLYAMKVLKKASLKVRDRVRTKMERDILVEVNHPFI 135
Query: 281 VKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLI 340
VKL + +++ L GG++F R +E D+K YL ++ L ++H G++
Sbjct: 136 VKLHYAFQTEGKLYLILDFLRGGDVFTRLSKEVLFTEEDVKFYLAELALALDHLHQLGIV 195
Query: 341 HFDIKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNF-GFFSSVAPELYSGNVLTTA 399
+ D+KPEN++ + +IK+ DFGL+K + + +F G +APE+ + + +
Sbjct: 196 YRDLKPENILLDEIG--HIKLTDFGLSKESVDQEKKAYSFCGTVEYMAPEVVNRRGHSQS 253
Query: 400 YDMWSVGILMGIGLLGYTPRIIGKRSRRLSVVFTSQEYL--CISGAALHFFGKCLHTNPS 457
D WS G+LM L G P R+ ++++ ++ + +S A NP+
Sbjct: 254 ADWWSYGVLMFEMLTGTLPFQGKDRNETMNMILKAKLGMPQFLSAEAQSLLRMLFKRNPA 313
Query: 458 RRL 460
RL
Sbjct: 314 NRL 316
>AF184965-1|AAF13190.1| 745|Homo sapiens ribosomal S6 kinase
protein.
Length = 745
Score = 103 bits (248), Expect = 2e-21
Identities = 73/253 (28%), Positives = 112/253 (44%), Gaps = 14/253 (5%)
Query: 232 IGSGVYGKVM-LIRSNAGKQFVAKTVISQYQTNSMEEYSTLRILRNTPNIVKLIECYSDG 290
IG G Y I + +F K +I + + + EE L PNI+ L + + DG
Sbjct: 432 IGVGSYSVCKRCIHATTNMEFAVK-IIDKSKRDPSEEIEILMRYGQHPNIITLKDVFDDG 490
Query: 291 LNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFDIKPENVM 350
V + + GG L DR +C SER+ L + + Y+H G++H D+KP N++
Sbjct: 491 RYVYLVTDLMKGGELLDRILKQKCFSEREASDILYVISKTVDYLHCQGVVHRDLKPSNIL 550
Query: 351 CC--SLNCLNIKIIDFGLTKCARSRTPINRNFGFFSS-VAPELYSGNVLTTAYDMWSVGI 407
S + +I+I DFG K R + + ++ VAPE+ A D+WS+G+
Sbjct: 551 YMDESASADSIRICDFGFAKQLRGENGLLLTPCYTANFVAPEVLMQQGYDAACDIWSLGV 610
Query: 408 LMGIGLLGYTPRIIGKRSRRLSVV---------FTSQEYLCISGAALHFFGKCLHTNPSR 458
L L GYTP G ++ + + IS A LH +P +
Sbjct: 611 LFYTMLAGYTPFANGPNDTPEEILLRIGNGKFSLSGGNWDNISDGAKDLLSHMLHMDPHQ 670
Query: 459 RLTAAQALNHPWM 471
R TA Q L H W+
Sbjct: 671 RYTAEQILKHSWI 683
Score = 93.1 bits (221), Expect = 3e-18
Identities = 66/243 (27%), Positives = 116/243 (47%), Gaps = 13/243 (5%)
Query: 229 LKLIGSGVYGKVMLIRSNAGK---QFVAKTVISQYQTNSMEEYST-----LRILRNTPNI 280
LK++G G +GKV L+R G Q A V+ + + T + + N P I
Sbjct: 76 LKVLGQGSFGKVFLVRKKTGPDAGQLYAMKVLKKASLKVRDRVRTKMERDILVEVNHPFI 135
Query: 281 VKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLI 340
VKL + +++ L GG++F R +E D+K YL ++ L ++H G++
Sbjct: 136 VKLHYAFQTEGKLYLILDFLRGGDVFTRLSKEVLFTEEDVKFYLAELALALDHLHQLGIV 195
Query: 341 HFDIKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNF-GFFSSVAPELYSGNVLTTA 399
+ D+KPEN++ + +IK+ DFGL+K + + +F G +APE+ + + +
Sbjct: 196 YRDLKPENILLDEIG--HIKLTDFGLSKESVDQEKKAYSFCGTVEYMAPEVVNRRGHSQS 253
Query: 400 YDMWSVGILMGIGLLGYTPRIIGKRSRRLSVVFTSQEYL--CISGAALHFFGKCLHTNPS 457
D WS G+LM L G P R+ ++++ ++ + +S A NP+
Sbjct: 254 ADWWSYGVLMFEMLTGTLPFQGKDRNETMNMILKAKLGMPQFLSAEAQSLLRMLFKRNPA 313
Query: 458 RRL 460
RL
Sbjct: 314 NRL 316
>X97630-1|CAA66229.1| 745|Homo sapiens serine/threonine protein
kinase protein.
Length = 745
Score = 103 bits (247), Expect = 2e-21
Identities = 95/313 (30%), Positives = 143/313 (45%), Gaps = 26/313 (8%)
Query: 229 LKLIGSGVYGKVMLIRSNAGKQFVAKTVISQYQTNS---MEEYSTLRILR--NTPNIVKL 283
LK IG G + KV L R + VA +I + Q NS + + +RI++ N PNIVKL
Sbjct: 23 LKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVLNHPNIVKL 82
Query: 284 IECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFD 343
E VME GG +FD H + E++ + RQ+ S +QY H ++H D
Sbjct: 83 FEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRD 142
Query: 344 IKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLT-TAYDM 402
+K EN++ + +NIKI DFG + ++ G APEL+ G D+
Sbjct: 143 LKAENLLLDA--DMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDGPEVDV 200
Query: 403 WSVGILMGIGLLGYTPRIIGKRSRRLSVVFTSQEY---LCISGAALHFFGKCLHTNPSRR 459
WS+G+++ + G P G+ + L +Y +S + K L NPS+R
Sbjct: 201 WSLGVILYTLVSGSLP-FDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPSKR 259
Query: 460 LTAAQALNHPWM------FDTCPH--PL-SWKKPSK-----NRRYNRYMGQRSSYGCDYL 505
T Q + WM + P+ PL +K P + + Y R Q S G Y
Sbjct: 260 GTLEQIMKDRWMNVGHEDDELKPYVEPLPDYKDPRRTELMVSMGYTREEIQDSLVGQRYN 319
Query: 506 KLMETFLLRNSKS 518
++M T+LL KS
Sbjct: 320 EVMATYLLLGYKS 332
>BT007342-1|AAP36006.1| 755|Homo sapiens MAP/microtubule
affinity-regulating kinase 2 protein.
Length = 755
Score = 103 bits (247), Expect = 2e-21
Identities = 95/313 (30%), Positives = 143/313 (45%), Gaps = 26/313 (8%)
Query: 229 LKLIGSGVYGKVMLIRSNAGKQFVAKTVISQYQTNS---MEEYSTLRILR--NTPNIVKL 283
LK IG G + KV L R + VA +I + Q NS + + +RI++ N PNIVKL
Sbjct: 23 LKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVLNHPNIVKL 82
Query: 284 IECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFD 343
E VME GG +FD H + E++ + RQ+ S +QY H ++H D
Sbjct: 83 FEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRD 142
Query: 344 IKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLT-TAYDM 402
+K EN++ + +NIKI DFG + ++ G APEL+ G D+
Sbjct: 143 LKAENLLLDA--DMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDGPEVDV 200
Query: 403 WSVGILMGIGLLGYTPRIIGKRSRRLSVVFTSQEY---LCISGAALHFFGKCLHTNPSRR 459
WS+G+++ + G P G+ + L +Y +S + K L NPS+R
Sbjct: 201 WSLGVILYTLVSGSLP-FDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPSKR 259
Query: 460 LTAAQALNHPWM------FDTCPH--PL-SWKKPSK-----NRRYNRYMGQRSSYGCDYL 505
T Q + WM + P+ PL +K P + + Y R Q S G Y
Sbjct: 260 GTLEQIMKDRWMNVGHEDDELKPYVEPLPDYKDPRRTELMVSMGYTREEIQDSLVGQRYN 319
Query: 506 KLMETFLLRNSKS 518
++M T+LL KS
Sbjct: 320 EVMATYLLLGYKS 332
>BC084540-1|AAH84540.1| 724|Homo sapiens MAP/microtubule
affinity-regulating kinase 2 protein.
Length = 724
Score = 103 bits (247), Expect = 2e-21
Identities = 95/313 (30%), Positives = 143/313 (45%), Gaps = 26/313 (8%)
Query: 229 LKLIGSGVYGKVMLIRSNAGKQFVAKTVISQYQTNS---MEEYSTLRILR--NTPNIVKL 283
LK IG G + KV L R + VA +I + Q NS + + +RI++ N PNIVKL
Sbjct: 56 LKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVLNHPNIVKL 115
Query: 284 IECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFD 343
E VME GG +FD H + E++ + RQ+ S +QY H ++H D
Sbjct: 116 FEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRD 175
Query: 344 IKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLT-TAYDM 402
+K EN++ + +NIKI DFG + ++ G APEL+ G D+
Sbjct: 176 LKAENLLLDA--DMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDGPEVDV 233
Query: 403 WSVGILMGIGLLGYTPRIIGKRSRRLSVVFTSQEY---LCISGAALHFFGKCLHTNPSRR 459
WS+G+++ + G P G+ + L +Y +S + K L NPS+R
Sbjct: 234 WSLGVILYTLVSGSLP-FDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPSKR 292
Query: 460 LTAAQALNHPWM------FDTCPH--PL-SWKKPSK-----NRRYNRYMGQRSSYGCDYL 505
T Q + WM + P+ PL +K P + + Y R Q S G Y
Sbjct: 293 GTLEQIMKDRWMNVGHEDDELKPYVEPLPDYKDPRRTELMVSMGYTREEIQDSLVGQRYN 352
Query: 506 KLMETFLLRNSKS 518
++M T+LL KS
Sbjct: 353 EVMATYLLLGYKS 365
>BC008771-1|AAH08771.2| 778|Homo sapiens MARK2 protein protein.
Length = 778
Score = 103 bits (247), Expect = 2e-21
Identities = 95/313 (30%), Positives = 143/313 (45%), Gaps = 26/313 (8%)
Query: 229 LKLIGSGVYGKVMLIRSNAGKQFVAKTVISQYQTNS---MEEYSTLRILR--NTPNIVKL 283
LK IG G + KV L R + VA +I + Q NS + + +RI++ N PNIVKL
Sbjct: 46 LKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVLNHPNIVKL 105
Query: 284 IECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFD 343
E VME GG +FD H + E++ + RQ+ S +QY H ++H D
Sbjct: 106 FEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRD 165
Query: 344 IKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLT-TAYDM 402
+K EN++ + +NIKI DFG + ++ G APEL+ G D+
Sbjct: 166 LKAENLLLDA--DMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDGPEVDV 223
Query: 403 WSVGILMGIGLLGYTPRIIGKRSRRLSVVFTSQEY---LCISGAALHFFGKCLHTNPSRR 459
WS+G+++ + G P G+ + L +Y +S + K L NPS+R
Sbjct: 224 WSLGVILYTLVSGSLP-FDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPSKR 282
Query: 460 LTAAQALNHPWM------FDTCPH--PL-SWKKPSK-----NRRYNRYMGQRSSYGCDYL 505
T Q + WM + P+ PL +K P + + Y R Q S G Y
Sbjct: 283 GTLEQIMKDRWMNVGHEDDELKPYVEPLPDYKDPRRTELMVSMGYTREEIQDSLVGQRYN 342
Query: 506 KLMETFLLRNSKS 518
++M T+LL KS
Sbjct: 343 EVMATYLLLGYKS 355
>AF387638-1|AAK82368.1| 691|Homo sapiens Ser/Thr protein kinase
PAR-1Balpha protein.
Length = 691
Score = 103 bits (247), Expect = 2e-21
Identities = 95/313 (30%), Positives = 143/313 (45%), Gaps = 26/313 (8%)
Query: 229 LKLIGSGVYGKVMLIRSNAGKQFVAKTVISQYQTNS---MEEYSTLRILR--NTPNIVKL 283
LK IG G + KV L R + VA +I + Q NS + + +RI++ N PNIVKL
Sbjct: 23 LKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVLNHPNIVKL 82
Query: 284 IECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFD 343
E VME GG +FD H + E++ + RQ+ S +QY H ++H D
Sbjct: 83 FEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRD 142
Query: 344 IKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLT-TAYDM 402
+K EN++ + +NIKI DFG + ++ G APEL+ G D+
Sbjct: 143 LKAENLLLDA--DMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDGPEVDV 200
Query: 403 WSVGILMGIGLLGYTPRIIGKRSRRLSVVFTSQEY---LCISGAALHFFGKCLHTNPSRR 459
WS+G+++ + G P G+ + L +Y +S + K L NPS+R
Sbjct: 201 WSLGVILYTLVSGSLP-FDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPSKR 259
Query: 460 LTAAQALNHPWM------FDTCPH--PL-SWKKPSK-----NRRYNRYMGQRSSYGCDYL 505
T Q + WM + P+ PL +K P + + Y R Q S G Y
Sbjct: 260 GTLEQIMKDRWMNVGHEDDELKPYVEPLPDYKDPRRTELMVSMGYTREEIQDSLVGQRYN 319
Query: 506 KLMETFLLRNSKS 518
++M T+LL KS
Sbjct: 320 EVMATYLLLGYKS 332
>AB188493-1|BAD37141.1| 719|Homo sapiens serine/threonine kinase
protein.
Length = 719
Score = 103 bits (247), Expect = 2e-21
Identities = 95/313 (30%), Positives = 143/313 (45%), Gaps = 26/313 (8%)
Query: 229 LKLIGSGVYGKVMLIRSNAGKQFVAKTVISQYQTNS---MEEYSTLRILR--NTPNIVKL 283
LK IG G + KV L R + VA +I + Q NS + + +RI++ N PNIVKL
Sbjct: 56 LKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVLNHPNIVKL 115
Query: 284 IECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFD 343
E VME GG +FD H + E++ + RQ+ S +QY H ++H D
Sbjct: 116 FEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRD 175
Query: 344 IKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLT-TAYDM 402
+K EN++ + +NIKI DFG + ++ G APEL+ G D+
Sbjct: 176 LKAENLLLDA--DMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDGPEVDV 233
Query: 403 WSVGILMGIGLLGYTPRIIGKRSRRLSVVFTSQEY---LCISGAALHFFGKCLHTNPSRR 459
WS+G+++ + G P G+ + L +Y +S + K L NPS+R
Sbjct: 234 WSLGVILYTLVSGSLP-FDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPSKR 292
Query: 460 LTAAQALNHPWM------FDTCPH--PL-SWKKPSK-----NRRYNRYMGQRSSYGCDYL 505
T Q + WM + P+ PL +K P + + Y R Q S G Y
Sbjct: 293 GTLEQIMKDRWMNVGHEDDELKPYVEPLPDYKDPRRTELMVSMGYTREEIQDSLVGQRYN 352
Query: 506 KLMETFLLRNSKS 518
++M T+LL KS
Sbjct: 353 EVMATYLLLGYKS 365
>AB051552-1|BAB21856.1| 608|Homo sapiens KIAA1765 protein protein.
Length = 608
Score = 103 bits (247), Expect = 2e-21
Identities = 74/256 (28%), Positives = 121/256 (47%), Gaps = 16/256 (6%)
Query: 230 KLIGSGVYGKVMLIRSNAGKQFVAKTVISQYQTNSMEEY--STLRILRNT--PNIVKLIE 285
++IG G + V R +Q A +I + + E+ S + I+++ PNIVKL E
Sbjct: 320 RVIGDGNFAVVKECRHRETRQAYAMKIIDKSRLKGKEDMVDSEILIIQSLSHPNIVKLHE 379
Query: 286 CYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFDIK 345
Y + ++E + GG+LFD E D + + +C L ++H+ ++H D+K
Sbjct: 380 VYETDMEIYLILEYVQGGDLFDAIIESVKFPEPDAALMIMDLCKALVHMHDKSIVHRDLK 439
Query: 346 PENVMC--CSLNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLTTAYDMW 403
PEN++ +K+ DFGL K PI G + VAPE+ S DMW
Sbjct: 440 PENLLVQRNEDKSTTLKLADFGLAK--HVVRPIFTVCGTPTYVAPEILSEKGYGLEVDMW 497
Query: 404 SVGILMGIGLLGYTPRIIGKRSR--RLSVV------FTSQEYLCISGAALHFFGKCLHTN 455
+ G+++ I L G+ P +R + +++ F + IS AA + L +
Sbjct: 498 AAGVILYILLCGFPPFRSPERDQDELFNIIQLGHFEFLPPYWDNISDAAKDLVSRLLVVD 557
Query: 456 PSRRLTAAQALNHPWM 471
P +R TA Q L HPW+
Sbjct: 558 PKKRYTAHQVLQHPWI 573
>BC007753-1|AAH07753.1| 242|Homo sapiens Unknown (protein for
IMAGE:4110141) protein.
Length = 242
Score = 103 bits (246), Expect = 3e-21
Identities = 53/177 (29%), Positives = 94/177 (53%), Gaps = 7/177 (3%)
Query: 302 GGNLFDRFKHHQC-ISERDIKIYLRQVCSGLQYIHNNGLIHFDIKPENVMCCSLNCLNIK 360
GG LF+R ++E D +++RQ+C G+ ++H ++H D+KPEN++C + +K
Sbjct: 10 GGELFERIVDEDYHLTEVDTMVFVRQICDGILFMHKMRVLHLDLKPENILCVNTTGHLVK 69
Query: 361 IIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLTTAYDMWSVGILMGIGLLGYTPRI 420
IIDFGL + + NFG ++PE+ + + ++ DMWS+G++ + L G +P +
Sbjct: 70 IIDFGLARRYNPNEKLKVNFGTPEFLSPEVVNYDQISDKTDMWSMGVITYMLLSGLSPFL 129
Query: 421 IGKRSRRLSVV------FTSQEYLCISGAALHFFGKCLHTNPSRRLTAAQALNHPWM 471
+ L+ V F + + +S A F + + R+ AAQ L HPW+
Sbjct: 130 GDDDTETLNNVLSGNWYFDEETFEAVSDEAKDFVSNLIVKDQRARMNAAQCLAHPWL 186
>L07598-1|AAC82496.1| 540|Homo sapiens ribosomal protein S6 kinase
2 protein.
Length = 540
Score = 100 bits (240), Expect = 2e-20
Identities = 78/246 (31%), Positives = 120/246 (48%), Gaps = 15/246 (6%)
Query: 229 LKLIGSGVYGKVMLIR----SNAGKQFVAK-----TVISQYQTNSMEEYSTLRILRNTPN 279
LK++G G YGKV L+R S+AG+ + K T+ + + S E L + N P
Sbjct: 63 LKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRVRSKMERDILAEV-NHPF 121
Query: 280 IVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGL 339
IVKL + +++ L GG+LF R +E D+K YL ++ L ++H+ G+
Sbjct: 122 IVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLGI 181
Query: 340 IHFDIKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNF-GFFSSVAPELYSGNVLTT 398
I+ D+KPEN++ +IKI DFGL+K A +F G +APE+ + T
Sbjct: 182 IYRDLKPENILLDEEG--HIKITDFGLSKEAIDHDKRAYSFCGTIEYMAPEVVNRRGHTQ 239
Query: 399 AYDMWSVGILMGIGLLGYTPRIIGKRSRRLSVVFTSQEYL--CISGAALHFFGKCLHTNP 456
+ D WS G+LM L G P R +S++ ++ + +SG A NP
Sbjct: 240 SADWWSFGVLMFEMLTGALPFQGKDRKETMSLILKAKLGMPQFLSGEAQSLLRALFKRNP 299
Query: 457 SRRLTA 462
RL A
Sbjct: 300 CNRLGA 305
Score = 66.1 bits (154), Expect = 4e-10
Identities = 37/119 (31%), Positives = 55/119 (46%)
Query: 232 IGSGVYGKVMLIRSNAGKQFVAKTVISQYQTNSMEEYSTLRILRNTPNIVKLIECYSDGL 291
IG G Y A A +I + + + EE L PNI+ L + Y DG
Sbjct: 422 IGVGSYSVCKRCVHKATDTEYAVKIIGKSKRDPSEEIEILLRYGQHPNIITLKDVYDDGK 481
Query: 292 NWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFDIKPENVM 350
VME + GG L DR + SER+ L + + Y+H+ G++H D+KP N++
Sbjct: 482 FVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLHSQGVVHRDLKPSNIL 540
>BC032784-1|AAH32784.1| 478|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II delta protein.
Length = 478
Score = 100 bits (240), Expect = 2e-20
Identities = 70/255 (27%), Positives = 124/255 (48%), Gaps = 17/255 (6%)
Query: 232 IGSGVYGKVM-LIRSNAGKQFVAKTV----ISQYQTNSMEEYSTLRILRNTPNIVKLIEC 286
+G G + V ++ G+++ AK + +S +E + + L PNIV+L +
Sbjct: 20 LGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDS 79
Query: 287 YSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFDIKP 346
S+ V + + GG LF+ + SE D ++Q+ + + H NG++H D+KP
Sbjct: 80 ISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGIVHRDLKP 139
Query: 347 ENVMCCSLN-CLNIKIIDFGLTKCARSRTPINRNFGFFSS---VAPELYSGNVLTTAYDM 402
EN++ S + +K+ DFGL + FGF + ++PE+ + DM
Sbjct: 140 ENLLLASKSKGAAVKLADFGL--AIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPVDM 197
Query: 403 WSVGILMGIGLLGYTPRIIGKRSRRLSVV------FTSQEYLCISGAALHFFGKCLHTNP 456
W+ G+++ I L+GY P + R + F S E+ ++ A K L NP
Sbjct: 198 WACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINP 257
Query: 457 SRRLTAAQALNHPWM 471
++R+TA++AL HPW+
Sbjct: 258 AKRITASEALKHPWI 272
>AB209288-1|BAD92525.1| 522|Homo sapiens
calcium/calmodulin-dependent protein kinase II delta
isoform 1 variant protein.
Length = 522
Score = 100 bits (240), Expect = 2e-20
Identities = 70/255 (27%), Positives = 124/255 (48%), Gaps = 17/255 (6%)
Query: 232 IGSGVYGKVM-LIRSNAGKQFVAKTV----ISQYQTNSMEEYSTLRILRNTPNIVKLIEC 286
+G G + V ++ G+++ AK + +S +E + + L PNIV+L +
Sbjct: 50 LGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDS 109
Query: 287 YSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFDIKP 346
S+ V + + GG LF+ + SE D ++Q+ + + H NG++H D+KP
Sbjct: 110 ISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGIVHRDLKP 169
Query: 347 ENVMCCSLN-CLNIKIIDFGLTKCARSRTPINRNFGFFSS---VAPELYSGNVLTTAYDM 402
EN++ S + +K+ DFGL + FGF + ++PE+ + DM
Sbjct: 170 ENLLLASKSKGAAVKLADFGL--AIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPVDM 227
Query: 403 WSVGILMGIGLLGYTPRIIGKRSRRLSVV------FTSQEYLCISGAALHFFGKCLHTNP 456
W+ G+++ I L+GY P + R + F S E+ ++ A K L NP
Sbjct: 228 WACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINP 287
Query: 457 SRRLTAAQALNHPWM 471
++R+TA++AL HPW+
Sbjct: 288 AKRITASEALKHPWI 302
>AY987011-1|AAX88806.1| 489|Homo sapiens
calcium/calmodulin-dependent protein kinase II delta
protein.
Length = 489
Score = 100 bits (239), Expect = 2e-20
Identities = 70/254 (27%), Positives = 123/254 (48%), Gaps = 17/254 (6%)
Query: 232 IGSGVYGKVM-LIRSNAGKQFVAKTV----ISQYQTNSMEEYSTLRILRNTPNIVKLIEC 286
+G G + V ++ G+++ AK + +S +E + + L PNIV+L +
Sbjct: 20 LGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDS 79
Query: 287 YSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFDIKP 346
S+ V + + GG LF+ + SE D ++Q+ + + H NG++H D+KP
Sbjct: 80 ISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGIVHRDLKP 139
Query: 347 ENVMCCSLN-CLNIKIIDFGLTKCARSRTPINRNFGFFSS---VAPELYSGNVLTTAYDM 402
EN++ S + +K+ DFGL + FGF + ++PE+ + DM
Sbjct: 140 ENLLLASKSKGAAVKLADFGL--AIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPVDM 197
Query: 403 WSVGILMGIGLLGYTPRIIGKRSRRLSVV------FTSQEYLCISGAALHFFGKCLHTNP 456
W+ G+++ I L+GY P + R + F S E+ ++ A K L NP
Sbjct: 198 WACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINP 257
Query: 457 SRRLTAAQALNHPW 470
++R+TA++AL HPW
Sbjct: 258 AKRITASEALKHPW 271
>D79997-1|BAA11492.2| 656|Homo sapiens KIAA0175 protein.
Length = 656
Score = 99.5 bits (237), Expect = 4e-20
Identities = 75/272 (27%), Positives = 133/272 (48%), Gaps = 27/272 (9%)
Query: 232 IGSGVYGKVMLIRSNAGKQFVAKTVISQYQTNS-----MEEYSTLRILRNTPNIVKLIEC 286
IG+G + KV L + VA ++ + S E L+ LR+ +I +L
Sbjct: 22 IGTGGFAKVKLACHILTGEMVAIKIMDKNTLGSDLPRIKTEIEALKNLRHQ-HICQLYHV 80
Query: 287 YSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFDIKP 346
V+E GG LFD +SE + ++ RQ+ S + Y+H+ G H D+KP
Sbjct: 81 LETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKP 140
Query: 347 ENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNF------GFFSSVAPELYSG-NVLTTA 399
EN++ + +K+IDFGL CA+ + N+++ G + APEL G + L +
Sbjct: 141 ENLLFDEYH--KLKLIDFGL--CAKPKG--NKDYHLQTCCGSLAYAAPELIQGKSYLGSE 194
Query: 400 YDMWSVGILMGIGLLGYTP----RIIGKRSRRLSVVFTSQEYLCISGAALHFFGKCLHTN 455
D+WS+GIL+ + + G+ P ++ + + + ++L S +++ + L +
Sbjct: 195 ADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRGKYDVPKWL--SPSSILLLQQMLQVD 252
Query: 456 PSRRLTAAQALNHPWMFDTCPHPLSWKKPSKN 487
P +R++ LNHPW+ +P+ W+ SKN
Sbjct: 253 PKKRISMKNLLNHPWIMQDYNYPVEWQ--SKN 282
>BC014039-1|AAH14039.1| 651|Homo sapiens maternal embryonic leucine
zipper kinase protein.
Length = 651
Score = 99.5 bits (237), Expect = 4e-20
Identities = 75/272 (27%), Positives = 133/272 (48%), Gaps = 27/272 (9%)
Query: 232 IGSGVYGKVMLIRSNAGKQFVAKTVISQYQTNS-----MEEYSTLRILRNTPNIVKLIEC 286
IG+G + KV L + VA ++ + S E L+ LR+ +I +L
Sbjct: 17 IGTGGFAKVKLACHILTGEMVAIKIMDKNTLGSDLPRIKTEIEALKNLRHQ-HICQLYHV 75
Query: 287 YSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFDIKP 346
V+E GG LFD +SE + ++ RQ+ S + Y+H+ G H D+KP
Sbjct: 76 LETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKP 135
Query: 347 ENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNF------GFFSSVAPELYSG-NVLTTA 399
EN++ + +K+IDFGL CA+ + N+++ G + APEL G + L +
Sbjct: 136 ENLLFDEYH--KLKLIDFGL--CAKPKG--NKDYHLQTCCGSLAYAAPELIQGKSYLGSE 189
Query: 400 YDMWSVGILMGIGLLGYTP----RIIGKRSRRLSVVFTSQEYLCISGAALHFFGKCLHTN 455
D+WS+GIL+ + + G+ P ++ + + + ++L S +++ + L +
Sbjct: 190 ADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRGKYDVPKWL--SPSSILLLQQMLQVD 247
Query: 456 PSRRLTAAQALNHPWMFDTCPHPLSWKKPSKN 487
P +R++ LNHPW+ +P+ W+ SKN
Sbjct: 248 PKKRISMKNLLNHPWIMQDYNYPVEWQ--SKN 277
>AL442063-1|CAI16995.2| 651|Homo sapiens maternal embryonic leucine
zipper kinase protein.
Length = 651
Score = 99.5 bits (237), Expect = 4e-20
Identities = 75/272 (27%), Positives = 133/272 (48%), Gaps = 27/272 (9%)
Query: 232 IGSGVYGKVMLIRSNAGKQFVAKTVISQYQTNS-----MEEYSTLRILRNTPNIVKLIEC 286
IG+G + KV L + VA ++ + S E L+ LR+ +I +L
Sbjct: 17 IGTGGFAKVKLACHILTGEMVAIKIMDKNTLGSDLPRIKTEIEALKNLRHQ-HICQLYHV 75
Query: 287 YSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFDIKP 346
V+E GG LFD +SE + ++ RQ+ S + Y+H+ G H D+KP
Sbjct: 76 LETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKP 135
Query: 347 ENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNF------GFFSSVAPELYSG-NVLTTA 399
EN++ + +K+IDFGL CA+ + N+++ G + APEL G + L +
Sbjct: 136 ENLLFDEYH--KLKLIDFGL--CAKPKG--NKDYHLQTCCGSLAYAAPELIQGKSYLGSE 189
Query: 400 YDMWSVGILMGIGLLGYTP----RIIGKRSRRLSVVFTSQEYLCISGAALHFFGKCLHTN 455
D+WS+GIL+ + + G+ P ++ + + + ++L S +++ + L +
Sbjct: 190 ADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRGKYDVPKWL--SPSSILLLQQMLQVD 247
Query: 456 PSRRLTAAQALNHPWMFDTCPHPLSWKKPSKN 487
P +R++ LNHPW+ +P+ W+ SKN
Sbjct: 248 PKKRISMKNLLNHPWIMQDYNYPVEWQ--SKN 277
>AL354932-1|CAI11034.2| 651|Homo sapiens maternal embryonic leucine
zipper kinase protein.
Length = 651
Score = 99.5 bits (237), Expect = 4e-20
Identities = 75/272 (27%), Positives = 133/272 (48%), Gaps = 27/272 (9%)
Query: 232 IGSGVYGKVMLIRSNAGKQFVAKTVISQYQTNS-----MEEYSTLRILRNTPNIVKLIEC 286
IG+G + KV L + VA ++ + S E L+ LR+ +I +L
Sbjct: 17 IGTGGFAKVKLACHILTGEMVAIKIMDKNTLGSDLPRIKTEIEALKNLRHQ-HICQLYHV 75
Query: 287 YSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFDIKP 346
V+E GG LFD +SE + ++ RQ+ S + Y+H+ G H D+KP
Sbjct: 76 LETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKP 135
Query: 347 ENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNF------GFFSSVAPELYSG-NVLTTA 399
EN++ + +K+IDFGL CA+ + N+++ G + APEL G + L +
Sbjct: 136 ENLLFDEYH--KLKLIDFGL--CAKPKG--NKDYHLQTCCGSLAYAAPELIQGKSYLGSE 189
Query: 400 YDMWSVGILMGIGLLGYTP----RIIGKRSRRLSVVFTSQEYLCISGAALHFFGKCLHTN 455
D+WS+GIL+ + + G+ P ++ + + + ++L S +++ + L +
Sbjct: 190 ADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRGKYDVPKWL--SPSSILLLQQMLQVD 247
Query: 456 PSRRLTAAQALNHPWMFDTCPHPLSWKKPSKN 487
P +R++ LNHPW+ +P+ W+ SKN
Sbjct: 248 PKKRISMKNLLNHPWIMQDYNYPVEWQ--SKN 277
>AK222811-1|BAD96531.1| 651|Homo sapiens maternal embryonic leucine
zipper kinase variant protein.
Length = 651
Score = 99.5 bits (237), Expect = 4e-20
Identities = 75/272 (27%), Positives = 133/272 (48%), Gaps = 27/272 (9%)
Query: 232 IGSGVYGKVMLIRSNAGKQFVAKTVISQYQTNS-----MEEYSTLRILRNTPNIVKLIEC 286
IG+G + KV L + VA ++ + S E L+ LR+ +I +L
Sbjct: 17 IGTGGFAKVKLACHILTGEMVAIKIMDKNTLGSDLPRIKTEIEALKNLRHQ-HICQLYHV 75
Query: 287 YSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFDIKP 346
V+E GG LFD +SE + ++ RQ+ S + Y+H+ G H D+KP
Sbjct: 76 LETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKP 135
Query: 347 ENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNF------GFFSSVAPELYSG-NVLTTA 399
EN++ + +K+IDFGL CA+ + N+++ G + APEL G + L +
Sbjct: 136 ENLLFDEYH--KLKLIDFGL--CAKPKG--NKDYHLQTCCGSLAYAAPELIQGKSYLGSE 189
Query: 400 YDMWSVGILMGIGLLGYTP----RIIGKRSRRLSVVFTSQEYLCISGAALHFFGKCLHTN 455
D+WS+GIL+ + + G+ P ++ + + + ++L S +++ + L +
Sbjct: 190 ADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRGKYDVPKWL--SPSSILLLQQMLQVD 247
Query: 456 PSRRLTAAQALNHPWMFDTCPHPLSWKKPSKN 487
P +R++ LNHPW+ +P+ W+ SKN
Sbjct: 248 PKKRISMKNLLNHPWIMQDYNYPVEWQ--SKN 277
>AF071569-1|AAD20442.1| 499|Homo sapiens multifunctional
calcium/calmodulin-dependent protein kinase II delta2
isoform protein.
Length = 499
Score = 99.1 bits (236), Expect = 5e-20
Identities = 70/255 (27%), Positives = 123/255 (48%), Gaps = 17/255 (6%)
Query: 232 IGSGVYGKVM-LIRSNAGKQFVAKTV----ISQYQTNSMEEYSTLRILRNTPNIVKLIEC 286
+G G + V ++ G+ + AK + +S +E + + L PNIV+L +
Sbjct: 20 LGKGAFSVVRRCMKIPTGQGYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDS 79
Query: 287 YSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFDIKP 346
S+ V + + GG LF+ + SE D ++Q+ + + H NG++H D+KP
Sbjct: 80 ISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGIVHRDLKP 139
Query: 347 ENVMCCSLN-CLNIKIIDFGLTKCARSRTPINRNFGFFSS---VAPELYSGNVLTTAYDM 402
EN++ S + +K+ DFGL + FGF + ++PE+ + DM
Sbjct: 140 ENLLLASKSKGAAVKLADFGL--AIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPVDM 197
Query: 403 WSVGILMGIGLLGYTPRIIGKRSRRLSVV------FTSQEYLCISGAALHFFGKCLHTNP 456
W+ G+++ I L+GY P + R + F S E+ ++ A K L NP
Sbjct: 198 WACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINP 257
Query: 457 SRRLTAAQALNHPWM 471
++R+TA++AL HPW+
Sbjct: 258 AKRITASEALKHPWI 272
>AL834498-1|CAD39156.1| 716|Homo sapiens hypothetical protein
protein.
Length = 716
Score = 98.7 bits (235), Expect = 6e-20
Identities = 77/260 (29%), Positives = 121/260 (46%), Gaps = 20/260 (7%)
Query: 230 KLIGSGVYGKVM-LIRSNAGKQFVAKTVISQYQTNSME-----EYSTLRILRNTPNIVKL 283
K+IG G + V I + GK+F K +I + + E E S LR +++ PNI+ L
Sbjct: 348 KVIGDGNFAVVKECIDRSTGKEFALK-IIDKAKCCGKEHLIENEVSILRRVKH-PNIIML 405
Query: 284 IECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFD 343
+E VME + GG+LFD +ERD + + + L+Y+H ++H D
Sbjct: 406 VEEMETATELFLVMELVKGGDLFDAITSSTKYTERDGSAMVYNLANALRYLHGLSIVHRD 465
Query: 344 IKPENVMCCSL--NCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLTTAYD 401
IKPEN++ C ++K+ DFGL P+ G + VAPE+ + D
Sbjct: 466 IKPENLLVCEYPDGTKSLKLGDFGLATVVEG--PLYTVCGTPTYVAPEIIAETGYGLKVD 523
Query: 402 MWSVGILMGIGLLGYTP-RIIGKRSRRL-------SVVFTSQEYLCISGAALHFFGKCLH 453
+W+ G++ I L G+ P R L + F + + I+ +A + L
Sbjct: 524 IWAAGVITYILLCGFPPFRSENNLQEDLFDQILAGKLEFPAPYWDNITDSAKELISQMLQ 583
Query: 454 TNPSRRLTAAQALNHPWMFD 473
N R TA Q L+HPW+ D
Sbjct: 584 VNVEARCTAGQILSHPWVSD 603
>AC093748-1|AAY40983.1| 443|Homo sapiens unknown protein.
Length = 443
Score = 98.7 bits (235), Expect = 6e-20
Identities = 77/260 (29%), Positives = 121/260 (46%), Gaps = 20/260 (7%)
Query: 230 KLIGSGVYGKVM-LIRSNAGKQFVAKTVISQYQTNSME-----EYSTLRILRNTPNIVKL 283
K+IG G + V I + GK+F K +I + + E E S LR +++ PNI+ L
Sbjct: 145 KVIGDGNFAVVKECIDRSTGKEFALK-IIDKAKCCGKEHLIENEVSILRRVKH-PNIIML 202
Query: 284 IECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFD 343
+E VME + GG+LFD +ERD + + + L+Y+H ++H D
Sbjct: 203 VEEMETATELFLVMELVKGGDLFDAITSSTKYTERDGSAMVYNLANALRYLHGLSIVHRD 262
Query: 344 IKPENVMCCSL--NCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLTTAYD 401
IKPEN++ C ++K+ DFGL P+ G + VAPE+ + D
Sbjct: 263 IKPENLLVCEYPDGTKSLKLGDFGLATVVEG--PLYTVCGTPTYVAPEIIAETGYGLKVD 320
Query: 402 MWSVGILMGIGLLGYTP-RIIGKRSRRL-------SVVFTSQEYLCISGAALHFFGKCLH 453
+W+ G++ I L G+ P R L + F + + I+ +A + L
Sbjct: 321 IWAAGVITYILLCGFPPFRSENNLQEDLFDQILAGKLEFPAPYWDNITDSAKELISQMLQ 380
Query: 454 TNPSRRLTAAQALNHPWMFD 473
N R TA Q L+HPW+ D
Sbjct: 381 VNVEARCTAGQILSHPWVSD 400
>AB209181-1|BAD92418.1| 796|Homo sapiens Hypothetical protein
DKFZp761I032 variant protein.
Length = 796
Score = 98.7 bits (235), Expect = 6e-20
Identities = 77/260 (29%), Positives = 121/260 (46%), Gaps = 20/260 (7%)
Query: 230 KLIGSGVYGKVM-LIRSNAGKQFVAKTVISQYQTNSME-----EYSTLRILRNTPNIVKL 283
K+IG G + V I + GK+F K +I + + E E S LR +++ PNI+ L
Sbjct: 428 KVIGDGNFAVVKECIDRSTGKEFALK-IIDKAKCCGKEHLIENEVSILRRVKH-PNIIML 485
Query: 284 IECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFD 343
+E VME + GG+LFD +ERD + + + L+Y+H ++H D
Sbjct: 486 VEEMETATELFLVMELVKGGDLFDAITSSTKYTERDGSAMVYNLANALRYLHGLSIVHRD 545
Query: 344 IKPENVMCCSL--NCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLTTAYD 401
IKPEN++ C ++K+ DFGL P+ G + VAPE+ + D
Sbjct: 546 IKPENLLVCEYPDGTKSLKLGDFGLATVVEG--PLYTVCGTPTYVAPEIIAETGYGLKVD 603
Query: 402 MWSVGILMGIGLLGYTP-RIIGKRSRRL-------SVVFTSQEYLCISGAALHFFGKCLH 453
+W+ G++ I L G+ P R L + F + + I+ +A + L
Sbjct: 604 IWAAGVITYILLCGFPPFRSENNLQEDLFDQILAGKLEFPAPYWDNITDSAKELISQMLQ 663
Query: 454 TNPSRRLTAAQALNHPWMFD 473
N R TA Q L+HPW+ D
Sbjct: 664 VNVEARCTAGQILSHPWVSD 683
>AL136373-4|CAI14764.1| 424|Homo sapiens MAP kinase interacting
serine/threonine kinase 1 protein.
Length = 424
Score = 98.3 bits (234), Expect = 8e-20
Identities = 80/300 (26%), Positives = 130/300 (43%), Gaps = 41/300 (13%)
Query: 218 SLQNFYRDFLPL--KLIGSGVYGKVM-LIRSNAGKQFVAKTVISQY---QTNSMEEYSTL 271
SL + D L +L+G G Y KV + GK++ K + Q ++ E TL
Sbjct: 39 SLPGKFEDMYKLTSELLGEGAYAKVQGAVSLQNGKEYAVKIIEKQAGHSRSRVFREVETL 98
Query: 272 RILRNTPNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGL 331
+ NI++LIE + D + V E L GG++ + + +ER+ +R V + L
Sbjct: 99 YQCQGNKNILELIEFFEDDTRFYLVFEKLQGGSILAHIQKQKHFNEREASRVVRDVAAAL 158
Query: 332 QYIHNNGLIHFDIKPENVMCCSLNCLN-IKIIDFGL-------TKCARSRTP-INRNFGF 382
++H G+ H D+KPEN++C S ++ +KI DF L C TP + G
Sbjct: 159 DFLHTKGIAHRDLKPENILCESPEKVSPVKICDFDLGSGMKLNNSCTPITTPELTTPCGS 218
Query: 383 FSSVAPELY-----SGNVLTTAYDMWSVGILMGIGLLGYTPRI----------------- 420
+APE+ D+WS+G+++ I L GY P +
Sbjct: 219 AEYMAPEVVEVFTDQATFYDKRCDLWSLGVVLYIMLSGYPPFVGHCGADCGWDRGEVCRV 278
Query: 421 ----IGKRSRRLSVVFTSQEYLCISGAALHFFGKCLHTNPSRRLTAAQALNHPWMFDTCP 476
+ + + F +++ IS A K L + +RL+AAQ L HPW+ P
Sbjct: 279 CQNKLFESIQEGKYEFPDKDWAHISSEAKDLISKLLVRDAKQRLSAAQVLQHPWVQGQAP 338
>AB000409-1|BAA19885.1| 424|Homo sapiens MNK1 protein.
Length = 424
Score = 98.3 bits (234), Expect = 8e-20
Identities = 80/300 (26%), Positives = 130/300 (43%), Gaps = 41/300 (13%)
Query: 218 SLQNFYRDFLPL--KLIGSGVYGKVM-LIRSNAGKQFVAKTVISQY---QTNSMEEYSTL 271
SL + D L +L+G G Y KV + GK++ K + Q ++ E TL
Sbjct: 39 SLPGKFEDMYKLTSELLGEGAYAKVQGAVSLQNGKEYAVKIIEKQAGHSRSRVFREVETL 98
Query: 272 RILRNTPNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGL 331
+ NI++LIE + D + V E L GG++ + + +ER+ +R V + L
Sbjct: 99 YQCQGNKNILELIEFFEDDTRFYLVFEKLQGGSILAHIQKQKHFNEREASRVVRDVAAAL 158
Query: 332 QYIHNNGLIHFDIKPENVMCCSLNCLN-IKIIDFGL-------TKCARSRTP-INRNFGF 382
++H G+ H D+KPEN++C S ++ +KI DF L C TP + G
Sbjct: 159 DFLHTKGIAHRDLKPENILCESPEKVSPVKICDFDLGSGMKLNNSCTPITTPELTTPCGS 218
Query: 383 FSSVAPELY-----SGNVLTTAYDMWSVGILMGIGLLGYTPRI----------------- 420
+APE+ D+WS+G+++ I L GY P +
Sbjct: 219 AEYMAPEVVEVFTDQATFYDKRCDLWSLGVVLYIMLSGYPPFVGHCGADCGWDRGEVCRV 278
Query: 421 ----IGKRSRRLSVVFTSQEYLCISGAALHFFGKCLHTNPSRRLTAAQALNHPWMFDTCP 476
+ + + F +++ IS A K L + +RL+AAQ L HPW+ P
Sbjct: 279 CQNKLFESIQEGKYEFPDKDWAHISSEAKDLISKLLVRDAKQRLSAAQVLQHPWVQGQAP 338
>U66064-1|AAB80848.1| 315|Homo sapiens calcium/calmodulin-dependent
protein kinase II protein.
Length = 315
Score = 97.9 bits (233), Expect = 1e-19
Identities = 68/264 (25%), Positives = 127/264 (48%), Gaps = 15/264 (5%)
Query: 222 FYRDFLPLKLIGSGVYGKVM-LIRSNAGKQFVAKTV----ISQYQTNSMEEYSTLRILRN 276
F D+ + +G G + V ++ + +++ AK + +S +E + + L
Sbjct: 10 FTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLK 69
Query: 277 TPNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHN 336
PNIV+L + S+ V + + GG LF+ + SE D + Q+ + +IH
Sbjct: 70 HPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQ 129
Query: 337 NGLIHFDIKPENVMCCSLNCLN--IKIIDFGLTKCARSRTPINRNF-GFFSSVAPELYSG 393
+ ++H D+KPEN++ S C +K+ DFGL + F G ++PE+
Sbjct: 130 HDIVHRDLKPENLLLAS-KCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRK 188
Query: 394 NVLTTAYDMWSVGILMGIGLLGYTP------RIIGKRSRRLSVVFTSQEYLCISGAALHF 447
+ D+W+ G+++ I L+GY P + ++ + + F S E+ ++ A +
Sbjct: 189 DPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNL 248
Query: 448 FGKCLHTNPSRRLTAAQALNHPWM 471
+ L NP++R+TA QAL HPW+
Sbjct: 249 INQMLTINPAKRITADQALKHPWV 272
>BC069823-1|AAH69823.1| 552|Homo sapiens AMP-activated protein
kinase alpha 2 catalytic subunit protein.
Length = 552
Score = 97.9 bits (233), Expect = 1e-19
Identities = 75/266 (28%), Positives = 122/266 (45%), Gaps = 17/266 (6%)
Query: 232 IGSGVYGKVMLIRSNAGKQFVAKTVISQYQTNSME-------EYSTLRILRNTPNIVKLI 284
+G G +GKV + VA ++++ + S++ E L++ R+ P+I+KL
Sbjct: 22 LGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRH-PHIIKLY 80
Query: 285 ECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFDI 344
+ S ++ VME + GG LFD H + E + + +Q+ S + Y H + ++H D+
Sbjct: 81 QVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHRHMVVHRDL 140
Query: 345 KPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLT-TAYDMW 403
KPENV+ + +N KI DFGL+ + + G + APE+ SG + D+W
Sbjct: 141 KPENVLLDA--HMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIW 198
Query: 404 SVGILMGIGLLGYTP----RIIGKRSRRLSVVFTSQEYLCISGAALHFFGKCLHTNPSRR 459
S G+++ L G P + + VF EYL S A L L +P +R
Sbjct: 199 SCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRSVATL--LMHMLQVDPLKR 256
Query: 460 LTAAQALNHPWMFDTCPHPLSWKKPS 485
T H W P L + PS
Sbjct: 257 ATIKDIREHEWFKQDLPSYLFPEDPS 282
>BC069740-1|AAH69740.1| 552|Homo sapiens AMP-activated protein
kinase alpha 2 catalytic subunit protein.
Length = 552
Score = 97.9 bits (233), Expect = 1e-19
Identities = 75/266 (28%), Positives = 122/266 (45%), Gaps = 17/266 (6%)
Query: 232 IGSGVYGKVMLIRSNAGKQFVAKTVISQYQTNSME-------EYSTLRILRNTPNIVKLI 284
+G G +GKV + VA ++++ + S++ E L++ R+ P+I+KL
Sbjct: 22 LGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRH-PHIIKLY 80
Query: 285 ECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFDI 344
+ S ++ VME + GG LFD H + E + + +Q+ S + Y H + ++H D+
Sbjct: 81 QVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHRHMVVHRDL 140
Query: 345 KPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLT-TAYDMW 403
KPENV+ + +N KI DFGL+ + + G + APE+ SG + D+W
Sbjct: 141 KPENVLLDA--HMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIW 198
Query: 404 SVGILMGIGLLGYTP----RIIGKRSRRLSVVFTSQEYLCISGAALHFFGKCLHTNPSRR 459
S G+++ L G P + + VF EYL S A L L +P +R
Sbjct: 199 SCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRSVATL--LMHMLQVDPLKR 256
Query: 460 LTAAQALNHPWMFDTCPHPLSWKKPS 485
T H W P L + PS
Sbjct: 257 ATIKDIREHEWFKQDLPSYLFPEDPS 282
>BC069680-1|AAH69680.1| 552|Homo sapiens protein kinase,
AMP-activated, alpha 2 catalytic subunit protein.
Length = 552
Score = 97.9 bits (233), Expect = 1e-19
Identities = 75/266 (28%), Positives = 122/266 (45%), Gaps = 17/266 (6%)
Query: 232 IGSGVYGKVMLIRSNAGKQFVAKTVISQYQTNSME-------EYSTLRILRNTPNIVKLI 284
+G G +GKV + VA ++++ + S++ E L++ R+ P+I+KL
Sbjct: 22 LGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRH-PHIIKLY 80
Query: 285 ECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFDI 344
+ S ++ VME + GG LFD H + E + + +Q+ S + Y H + ++H D+
Sbjct: 81 QVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHRHMVVHRDL 140
Query: 345 KPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLT-TAYDMW 403
KPENV+ + +N KI DFGL+ + + G + APE+ SG + D+W
Sbjct: 141 KPENVLLDA--HMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIW 198
Query: 404 SVGILMGIGLLGYTP----RIIGKRSRRLSVVFTSQEYLCISGAALHFFGKCLHTNPSRR 459
S G+++ L G P + + VF EYL S A L L +P +R
Sbjct: 199 SCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRSVATL--LMHMLQVDPLKR 256
Query: 460 LTAAQALNHPWMFDTCPHPLSWKKPS 485
T H W P L + PS
Sbjct: 257 ATIKDIREHEWFKQDLPSYLFPEDPS 282
>AL713896-5|CAI13788.1| 516|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II gamma protein.
Length = 516
Score = 97.9 bits (233), Expect = 1e-19
Identities = 68/264 (25%), Positives = 127/264 (48%), Gaps = 15/264 (5%)
Query: 222 FYRDFLPLKLIGSGVYGKVM-LIRSNAGKQFVAKTV----ISQYQTNSMEEYSTLRILRN 276
F D+ + +G G + V ++ + +++ AK + +S +E + + L
Sbjct: 10 FTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLK 69
Query: 277 TPNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHN 336
PNIV+L + S+ V + + GG LF+ + SE D + Q+ + +IH
Sbjct: 70 HPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQ 129
Query: 337 NGLIHFDIKPENVMCCSLNCLN--IKIIDFGLTKCARSRTPINRNF-GFFSSVAPELYSG 393
+ ++H D+KPEN++ S C +K+ DFGL + F G ++PE+
Sbjct: 130 HDIVHRDLKPENLLLAS-KCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRK 188
Query: 394 NVLTTAYDMWSVGILMGIGLLGYTP------RIIGKRSRRLSVVFTSQEYLCISGAALHF 447
+ D+W+ G+++ I L+GY P + ++ + + F S E+ ++ A +
Sbjct: 189 DPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNL 248
Query: 448 FGKCLHTNPSRRLTAAQALNHPWM 471
+ L NP++R+TA QAL HPW+
Sbjct: 249 INQMLTINPAKRITADQALKHPWV 272
>AL713896-4|CAI13789.1| 495|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II gamma protein.
Length = 495
Score = 97.9 bits (233), Expect = 1e-19
Identities = 68/264 (25%), Positives = 127/264 (48%), Gaps = 15/264 (5%)
Query: 222 FYRDFLPLKLIGSGVYGKVM-LIRSNAGKQFVAKTV----ISQYQTNSMEEYSTLRILRN 276
F D+ + +G G + V ++ + +++ AK + +S +E + + L
Sbjct: 10 FTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLK 69
Query: 277 TPNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHN 336
PNIV+L + S+ V + + GG LF+ + SE D + Q+ + +IH
Sbjct: 70 HPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQ 129
Query: 337 NGLIHFDIKPENVMCCSLNCLN--IKIIDFGLTKCARSRTPINRNF-GFFSSVAPELYSG 393
+ ++H D+KPEN++ S C +K+ DFGL + F G ++PE+
Sbjct: 130 HDIVHRDLKPENLLLAS-KCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRK 188
Query: 394 NVLTTAYDMWSVGILMGIGLLGYTP------RIIGKRSRRLSVVFTSQEYLCISGAALHF 447
+ D+W+ G+++ I L+GY P + ++ + + F S E+ ++ A +
Sbjct: 189 DPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNL 248
Query: 448 FGKCLHTNPSRRLTAAQALNHPWM 471
+ L NP++R+TA QAL HPW+
Sbjct: 249 INQMLTINPAKRITADQALKHPWV 272
>AL713896-3|CAI13790.1| 529|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II gamma protein.
Length = 529
Score = 97.9 bits (233), Expect = 1e-19
Identities = 68/264 (25%), Positives = 127/264 (48%), Gaps = 15/264 (5%)
Query: 222 FYRDFLPLKLIGSGVYGKVM-LIRSNAGKQFVAKTV----ISQYQTNSMEEYSTLRILRN 276
F D+ + +G G + V ++ + +++ AK + +S +E + + L
Sbjct: 10 FTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLK 69
Query: 277 TPNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHN 336
PNIV+L + S+ V + + GG LF+ + SE D + Q+ + +IH
Sbjct: 70 HPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQ 129
Query: 337 NGLIHFDIKPENVMCCSLNCLN--IKIIDFGLTKCARSRTPINRNF-GFFSSVAPELYSG 393
+ ++H D+KPEN++ S C +K+ DFGL + F G ++PE+
Sbjct: 130 HDIVHRDLKPENLLLAS-KCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRK 188
Query: 394 NVLTTAYDMWSVGILMGIGLLGYTP------RIIGKRSRRLSVVFTSQEYLCISGAALHF 447
+ D+W+ G+++ I L+GY P + ++ + + F S E+ ++ A +
Sbjct: 189 DPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNL 248
Query: 448 FGKCLHTNPSRRLTAAQALNHPWM 471
+ L NP++R+TA QAL HPW+
Sbjct: 249 INQMLTINPAKRITADQALKHPWV 272
>AL713896-2|CAI13791.1| 527|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II gamma protein.
Length = 527
Score = 97.9 bits (233), Expect = 1e-19
Identities = 68/264 (25%), Positives = 127/264 (48%), Gaps = 15/264 (5%)
Query: 222 FYRDFLPLKLIGSGVYGKVM-LIRSNAGKQFVAKTV----ISQYQTNSMEEYSTLRILRN 276
F D+ + +G G + V ++ + +++ AK + +S +E + + L
Sbjct: 10 FTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLK 69
Query: 277 TPNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHN 336
PNIV+L + S+ V + + GG LF+ + SE D + Q+ + +IH
Sbjct: 70 HPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQ 129
Query: 337 NGLIHFDIKPENVMCCSLNCLN--IKIIDFGLTKCARSRTPINRNF-GFFSSVAPELYSG 393
+ ++H D+KPEN++ S C +K+ DFGL + F G ++PE+
Sbjct: 130 HDIVHRDLKPENLLLAS-KCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRK 188
Query: 394 NVLTTAYDMWSVGILMGIGLLGYTP------RIIGKRSRRLSVVFTSQEYLCISGAALHF 447
+ D+W+ G+++ I L+GY P + ++ + + F S E+ ++ A +
Sbjct: 189 DPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNL 248
Query: 448 FGKCLHTNPSRRLTAAQALNHPWM 471
+ L NP++R+TA QAL HPW+
Sbjct: 249 INQMLTINPAKRITADQALKHPWV 272
>AL596247-5|CAI13967.1| 516|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II gamma protein.
Length = 516
Score = 97.9 bits (233), Expect = 1e-19
Identities = 68/264 (25%), Positives = 127/264 (48%), Gaps = 15/264 (5%)
Query: 222 FYRDFLPLKLIGSGVYGKVM-LIRSNAGKQFVAKTV----ISQYQTNSMEEYSTLRILRN 276
F D+ + +G G + V ++ + +++ AK + +S +E + + L
Sbjct: 10 FTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLK 69
Query: 277 TPNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHN 336
PNIV+L + S+ V + + GG LF+ + SE D + Q+ + +IH
Sbjct: 70 HPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQ 129
Query: 337 NGLIHFDIKPENVMCCSLNCLN--IKIIDFGLTKCARSRTPINRNF-GFFSSVAPELYSG 393
+ ++H D+KPEN++ S C +K+ DFGL + F G ++PE+
Sbjct: 130 HDIVHRDLKPENLLLAS-KCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRK 188
Query: 394 NVLTTAYDMWSVGILMGIGLLGYTP------RIIGKRSRRLSVVFTSQEYLCISGAALHF 447
+ D+W+ G+++ I L+GY P + ++ + + F S E+ ++ A +
Sbjct: 189 DPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNL 248
Query: 448 FGKCLHTNPSRRLTAAQALNHPWM 471
+ L NP++R+TA QAL HPW+
Sbjct: 249 INQMLTINPAKRITADQALKHPWV 272
>AL596247-4|CAI13966.1| 495|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II gamma protein.
Length = 495
Score = 97.9 bits (233), Expect = 1e-19
Identities = 68/264 (25%), Positives = 127/264 (48%), Gaps = 15/264 (5%)
Query: 222 FYRDFLPLKLIGSGVYGKVM-LIRSNAGKQFVAKTV----ISQYQTNSMEEYSTLRILRN 276
F D+ + +G G + V ++ + +++ AK + +S +E + + L
Sbjct: 10 FTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLK 69
Query: 277 TPNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHN 336
PNIV+L + S+ V + + GG LF+ + SE D + Q+ + +IH
Sbjct: 70 HPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQ 129
Query: 337 NGLIHFDIKPENVMCCSLNCLN--IKIIDFGLTKCARSRTPINRNF-GFFSSVAPELYSG 393
+ ++H D+KPEN++ S C +K+ DFGL + F G ++PE+
Sbjct: 130 HDIVHRDLKPENLLLAS-KCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRK 188
Query: 394 NVLTTAYDMWSVGILMGIGLLGYTP------RIIGKRSRRLSVVFTSQEYLCISGAALHF 447
+ D+W+ G+++ I L+GY P + ++ + + F S E+ ++ A +
Sbjct: 189 DPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNL 248
Query: 448 FGKCLHTNPSRRLTAAQALNHPWM 471
+ L NP++R+TA QAL HPW+
Sbjct: 249 INQMLTINPAKRITADQALKHPWV 272
>AL596247-3|CAI13965.1| 529|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II gamma protein.
Length = 529
Score = 97.9 bits (233), Expect = 1e-19
Identities = 68/264 (25%), Positives = 127/264 (48%), Gaps = 15/264 (5%)
Query: 222 FYRDFLPLKLIGSGVYGKVM-LIRSNAGKQFVAKTV----ISQYQTNSMEEYSTLRILRN 276
F D+ + +G G + V ++ + +++ AK + +S +E + + L
Sbjct: 10 FTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLK 69
Query: 277 TPNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHN 336
PNIV+L + S+ V + + GG LF+ + SE D + Q+ + +IH
Sbjct: 70 HPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQ 129
Query: 337 NGLIHFDIKPENVMCCSLNCLN--IKIIDFGLTKCARSRTPINRNF-GFFSSVAPELYSG 393
+ ++H D+KPEN++ S C +K+ DFGL + F G ++PE+
Sbjct: 130 HDIVHRDLKPENLLLAS-KCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRK 188
Query: 394 NVLTTAYDMWSVGILMGIGLLGYTP------RIIGKRSRRLSVVFTSQEYLCISGAALHF 447
+ D+W+ G+++ I L+GY P + ++ + + F S E+ ++ A +
Sbjct: 189 DPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNL 248
Query: 448 FGKCLHTNPSRRLTAAQALNHPWM 471
+ L NP++R+TA QAL HPW+
Sbjct: 249 INQMLTINPAKRITADQALKHPWV 272
>AL596247-2|CAI13968.1| 527|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II gamma protein.
Length = 527
Score = 97.9 bits (233), Expect = 1e-19
Identities = 68/264 (25%), Positives = 127/264 (48%), Gaps = 15/264 (5%)
Query: 222 FYRDFLPLKLIGSGVYGKVM-LIRSNAGKQFVAKTV----ISQYQTNSMEEYSTLRILRN 276
F D+ + +G G + V ++ + +++ AK + +S +E + + L
Sbjct: 10 FTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLK 69
Query: 277 TPNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHN 336
PNIV+L + S+ V + + GG LF+ + SE D + Q+ + +IH
Sbjct: 70 HPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQ 129
Query: 337 NGLIHFDIKPENVMCCSLNCLN--IKIIDFGLTKCARSRTPINRNF-GFFSSVAPELYSG 393
+ ++H D+KPEN++ S C +K+ DFGL + F G ++PE+
Sbjct: 130 HDIVHRDLKPENLLLAS-KCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRK 188
Query: 394 NVLTTAYDMWSVGILMGIGLLGYTP------RIIGKRSRRLSVVFTSQEYLCISGAALHF 447
+ D+W+ G+++ I L+GY P + ++ + + F S E+ ++ A +
Sbjct: 189 DPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNL 248
Query: 448 FGKCLHTNPSRRLTAAQALNHPWM 471
+ L NP++R+TA QAL HPW+
Sbjct: 249 INQMLTINPAKRITADQALKHPWV 272
>AL035705-2|CAC17574.2| 552|Homo sapiens protein kinase,
AMP-activated, alpha 2 catalytic subunit protein.
Length = 552
Score = 97.9 bits (233), Expect = 1e-19
Identities = 75/266 (28%), Positives = 122/266 (45%), Gaps = 17/266 (6%)
Query: 232 IGSGVYGKVMLIRSNAGKQFVAKTVISQYQTNSME-------EYSTLRILRNTPNIVKLI 284
+G G +GKV + VA ++++ + S++ E L++ R+ P+I+KL
Sbjct: 22 LGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRH-PHIIKLY 80
Query: 285 ECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFDI 344
+ S ++ VME + GG LFD H + E + + +Q+ S + Y H + ++H D+
Sbjct: 81 QVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHRHMVVHRDL 140
Query: 345 KPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLT-TAYDMW 403
KPENV+ + +N KI DFGL+ + + G + APE+ SG + D+W
Sbjct: 141 KPENVLLDA--HMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIW 198
Query: 404 SVGILMGIGLLGYTP----RIIGKRSRRLSVVFTSQEYLCISGAALHFFGKCLHTNPSRR 459
S G+++ L G P + + VF EYL S A L L +P +R
Sbjct: 199 SCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRSVATL--LMHMLQVDPLKR 256
Query: 460 LTAAQALNHPWMFDTCPHPLSWKKPS 485
T H W P L + PS
Sbjct: 257 ATIKDIREHEWFKQDLPSYLFPEDPS 282
>U06454-1|AAA64745.1| 552|Homo sapiens AMP-activated protein kinase
protein.
Length = 552
Score = 97.5 bits (232), Expect = 1e-19
Identities = 75/266 (28%), Positives = 122/266 (45%), Gaps = 17/266 (6%)
Query: 232 IGSGVYGKVMLIRSNAGKQFVAKTVISQYQTNSME-------EYSTLRILRNTPNIVKLI 284
+G G +GKV + VA ++++ + S++ E L++ R+ P+I+KL
Sbjct: 22 LGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRH-PHIIKLY 80
Query: 285 ECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFDI 344
+ S ++ VME + GG LFD H + E + + +Q+ S + Y H + ++H D+
Sbjct: 81 QVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHRHMVVHRDL 140
Query: 345 KPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLT-TAYDMW 403
KPENV+ + +N KI DFGL+ + + G + APE+ SG + D+W
Sbjct: 141 KPENVLLDA--HMNAKIADFGLSNMMSDGEFLRTSCGSPNYTAPEVISGRLYAGPEVDIW 198
Query: 404 SVGILMGIGLLGYTP----RIIGKRSRRLSVVFTSQEYLCISGAALHFFGKCLHTNPSRR 459
S G+++ L G P + + VF EYL S A L L +P +R
Sbjct: 199 SCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRSVATL--LMHMLQVDPLKR 256
Query: 460 LTAAQALNHPWMFDTCPHPLSWKKPS 485
T H W P L + PS
Sbjct: 257 ATIKDIREHEWFKQGLPSYLFPEDPS 282
>EF056019-1|ABK30810.1| 552|Homo sapiens AMP-activated alpha 2
subunit protein.
Length = 552
Score = 97.5 bits (232), Expect = 1e-19
Identities = 75/266 (28%), Positives = 122/266 (45%), Gaps = 17/266 (6%)
Query: 232 IGSGVYGKVMLIRSNAGKQFVAKTVISQYQTNSME-------EYSTLRILRNTPNIVKLI 284
+G G +GKV + VA ++++ + S++ E L++ R+ P+I+KL
Sbjct: 22 LGVGTFGKVNIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRH-PHIIKLY 80
Query: 285 ECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFDI 344
+ S ++ VME + GG LFD H + E + + +Q+ S + Y H + ++H D+
Sbjct: 81 QVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHRHMVVHRDL 140
Query: 345 KPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLT-TAYDMW 403
KPENV+ + +N KI DFGL+ + + G + APE+ SG + D+W
Sbjct: 141 KPENVLLDA--HMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIW 198
Query: 404 SVGILMGIGLLGYTP----RIIGKRSRRLSVVFTSQEYLCISGAALHFFGKCLHTNPSRR 459
S G+++ L G P + + VF EYL S A L L +P +R
Sbjct: 199 SCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRSVATL--LMHMLQVDPLKR 256
Query: 460 LTAAQALNHPWMFDTCPHPLSWKKPS 485
T H W P L + PS
Sbjct: 257 ATIKDIREHEWFKQDLPSYLFPEDPS 282
>BC126182-1|AAI26183.1| 385|Homo sapiens protein serine kinase H2
protein.
Length = 385
Score = 97.5 bits (232), Expect = 1e-19
Identities = 82/281 (29%), Positives = 129/281 (45%), Gaps = 15/281 (5%)
Query: 231 LIGSGVYGKVMLIRSNAGKQFVAKTVISQYQTNSMEE-YSTLRILRNTPN--IVKLIECY 287
LIG+G + +V+ + K+ A V+ + E S L +LR + IV+L+E +
Sbjct: 68 LIGTGSFSRVVRVEQKTTKKPFAIKVMETREREGREACVSELSVLRRVSHRYIVQLMEIF 127
Query: 288 SDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFDIKPE 347
VME GG LFDR +ERD L+ V G++Y+H + H ++KPE
Sbjct: 128 ETEDQVYMVMELATGGELFDRLIAQGSFTERDAVRILQMVADGIRYLHALQITHRNLKPE 187
Query: 348 NVMCCSL-NCLNIKIIDFGLTKCARSR--TPINRNFGFFSSVAPELYSGNVLTTAYDMWS 404
N++ I I DFGL + + G +APE+ T+A DMW+
Sbjct: 188 NLLYYHPGEESKILITDFGLAYSGKKSGDWTMKTLCGTPEYIAPEVLLRKPYTSAVDMWA 247
Query: 405 VGILMGIGLLGYTPRIIGKRSRRLSVV------FTSQEYLCISGAALHFFGKCLHTNPSR 458
+G++ L G+ P ++R + +T + + IS A F K L
Sbjct: 248 LGVITYALLSGFLPFDDESQTRLYRKILKGKYNYTGEPWPSISHLAKDFIDKLLILEAGH 307
Query: 459 RLTAAQALNHPWMFDTCPHPLSWKKPSKNRRYNRYMGQRSS 499
R++A QAL+HPW+ T S K + R +R + QR+S
Sbjct: 308 RMSAGQALDHPWVI-TMAAGSSMK--NLQRAISRNLMQRAS 345
>BC126180-1|AAI26181.1| 385|Homo sapiens protein serine kinase H2
protein.
Length = 385
Score = 97.5 bits (232), Expect = 1e-19
Identities = 82/281 (29%), Positives = 129/281 (45%), Gaps = 15/281 (5%)
Query: 231 LIGSGVYGKVMLIRSNAGKQFVAKTVISQYQTNSMEE-YSTLRILRNTPN--IVKLIECY 287
LIG+G + +V+ + K+ A V+ + E S L +LR + IV+L+E +
Sbjct: 68 LIGTGSFSRVVRVEQKTTKKPFAIKVMETREREGREACVSELSVLRRVSHRYIVQLMEIF 127
Query: 288 SDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFDIKPE 347
VME GG LFDR +ERD L+ V G++Y+H + H ++KPE
Sbjct: 128 ETEDQVYMVMELATGGELFDRLIAQGSFTERDAVRILQMVADGIRYLHALQITHRNLKPE 187
Query: 348 NVMCCSL-NCLNIKIIDFGLTKCARSR--TPINRNFGFFSSVAPELYSGNVLTTAYDMWS 404
N++ I I DFGL + + G +APE+ T+A DMW+
Sbjct: 188 NLLYYHPGEESKILITDFGLAYSGKKSGDWTMKTLCGTPEYIAPEVLLRKPYTSAVDMWA 247
Query: 405 VGILMGIGLLGYTPRIIGKRSRRLSVV------FTSQEYLCISGAALHFFGKCLHTNPSR 458
+G++ L G+ P ++R + +T + + IS A F K L
Sbjct: 248 LGVITYALLSGFLPFDDESQTRLYRKILKGKYNYTGEPWPSISHLAKDFIDKLLILEAGH 307
Query: 459 RLTAAQALNHPWMFDTCPHPLSWKKPSKNRRYNRYMGQRSS 499
R++A QAL+HPW+ T S K + R +R + QR+S
Sbjct: 308 RMSAGQALDHPWVI-TMAAGSSMK--NLQRAISRNLMQRAS 345
>BC022558-1|AAH22558.1| 344|Homo sapiens CAMK2D protein protein.
Length = 344
Score = 97.5 bits (232), Expect = 1e-19
Identities = 69/255 (27%), Positives = 123/255 (48%), Gaps = 17/255 (6%)
Query: 232 IGSGVYGKVM-LIRSNAGKQFVAKTV----ISQYQTNSMEEYSTLRILRNTPNIVKLIEC 286
+G G + V ++ G+++ AK + +S +E + + L PNIV+L +
Sbjct: 20 LGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDS 79
Query: 287 YSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFDIKP 346
S+ V + + GG LF+ + SE D ++Q+ + + H G++H D+KP
Sbjct: 80 ISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKP 139
Query: 347 ENVMCCSLN-CLNIKIIDFGLTKCARSRTPINRNFGFFSS---VAPELYSGNVLTTAYDM 402
EN++ S + +K+ DFGL + FGF + ++PE+ + DM
Sbjct: 140 ENLLLASKSKGAAVKLADFGL--AIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPVDM 197
Query: 403 WSVGILMGIGLLGYTPRIIGKRSRRLSVV------FTSQEYLCISGAALHFFGKCLHTNP 456
W+ G+++ I L+GY P + R + F S E+ ++ A K L NP
Sbjct: 198 WACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINP 257
Query: 457 SRRLTAAQALNHPWM 471
++R+TA++AL HPW+
Sbjct: 258 AKRITASEALKHPWI 272
>AY355461-1|AAQ84219.1| 347|Homo sapiens MNK1-like kinase 1b
protein.
Length = 347
Score = 97.5 bits (232), Expect = 1e-19
Identities = 79/295 (26%), Positives = 129/295 (43%), Gaps = 41/295 (13%)
Query: 218 SLQNFYRDFLPL--KLIGSGVYGKVM-LIRSNAGKQFVAKTVISQY---QTNSMEEYSTL 271
SL + D L +L+G G Y KV + GK++ K + Q ++ E TL
Sbjct: 39 SLPGKFEDMYKLTSELLGEGAYAKVQGAVSLQNGKEYAVKIIEKQAGHSRSRVFREVETL 98
Query: 272 RILRNTPNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGL 331
+ NI++LIE + D + V E L GG++ + + +ER+ +R V + L
Sbjct: 99 YQCQGNKNILELIEFFEDDTRFYLVFEKLQGGSILAHIQKQKHFNEREASRVVRDVAAAL 158
Query: 332 QYIHNNGLIHFDIKPENVMCCSLNCLN-IKIIDFGL-------TKCARSRTP-INRNFGF 382
++H G+ H D+KPEN++C S ++ +KI DF L C TP + G
Sbjct: 159 DFLHTKGIAHRDLKPENILCESPEKVSPVKICDFDLGSGMKLNNSCTPITTPELTTPCGS 218
Query: 383 FSSVAPELY-----SGNVLTTAYDMWSVGILMGIGLLGYTPRI----------------- 420
+APE+ D+WS+G+++ I L GY P +
Sbjct: 219 AEYMAPEVVEVFTDQATFYDKRCDLWSLGVVLYIMLSGYPPFVGHCGADCGWDRGEVCRV 278
Query: 421 ----IGKRSRRLSVVFTSQEYLCISGAALHFFGKCLHTNPSRRLTAAQALNHPWM 471
+ + + F +++ IS A K L + +RL+AAQ L HPW+
Sbjct: 279 CQNKLFESIQEGKYEFPDKDWAHISSEAKDLISKLLVRDAKQRLSAAQVLQHPWV 333
>AY037806-1|AAK59985.1| 385|Homo sapiens serine/threonine kinase
PSKH2 protein.
Length = 385
Score = 97.5 bits (232), Expect = 1e-19
Identities = 82/281 (29%), Positives = 129/281 (45%), Gaps = 15/281 (5%)
Query: 231 LIGSGVYGKVMLIRSNAGKQFVAKTVISQYQTNSMEE-YSTLRILRNTPN--IVKLIECY 287
LIG+G + +V+ + K+ A V+ + E S L +LR + IV+L+E +
Sbjct: 68 LIGTGSFSRVVRVEQKTTKKPFAIKVMETREREGREACVSELSVLRRVSHRYIVQLMEIF 127
Query: 288 SDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFDIKPE 347
VME GG LFDR +ERD L+ V G++Y+H + H ++KPE
Sbjct: 128 ETEDQVYMVMELATGGELFDRLIAQGSFTERDAVRILQMVADGIRYLHALQITHRNLKPE 187
Query: 348 NVMCCSL-NCLNIKIIDFGLTKCARSR--TPINRNFGFFSSVAPELYSGNVLTTAYDMWS 404
N++ I I DFGL + + G +APE+ T+A DMW+
Sbjct: 188 NLLYYHPGEESKILITDFGLAYSGKKSGDWTMKTLCGTPEYIAPEVLLRKPYTSAVDMWA 247
Query: 405 VGILMGIGLLGYTPRIIGKRSRRLSVV------FTSQEYLCISGAALHFFGKCLHTNPSR 458
+G++ L G+ P ++R + +T + + IS A F K L
Sbjct: 248 LGVITYALLSGFLPFDDESQTRLYRKILKGKYNYTGEPWPSISHLAKDFIDKLLILEAGH 307
Query: 459 RLTAAQALNHPWMFDTCPHPLSWKKPSKNRRYNRYMGQRSS 499
R++A QAL+HPW+ T S K + R +R + QR+S
Sbjct: 308 RMSAGQALDHPWVI-TMAAGSSMK--NLQRAISRNLMQRAS 345
>BC034044-1|AAH34044.1| 527|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II gamma protein.
Length = 527
Score = 97.1 bits (231), Expect = 2e-19
Identities = 68/264 (25%), Positives = 126/264 (47%), Gaps = 15/264 (5%)
Query: 222 FYRDFLPLKLIGSGVYGKVM-LIRSNAGKQFVAKTV----ISQYQTNSMEEYSTLRILRN 276
F D+ + +G G + V ++ +++ AK + +S +E + + L
Sbjct: 10 FTDDYQLFEELGKGAFSVVRRCVKKTPTQEYAAKIINTKKLSARDHQKLEREARICRLLK 69
Query: 277 TPNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHN 336
PNIV+L + S+ V + + GG LF+ + SE D + Q+ + +IH
Sbjct: 70 HPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQ 129
Query: 337 NGLIHFDIKPENVMCCSLNCLN--IKIIDFGLTKCARSRTPINRNF-GFFSSVAPELYSG 393
+ ++H D+KPEN++ S C +K+ DFGL + F G ++PE+
Sbjct: 130 HDIVHRDLKPENLLLAS-KCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRK 188
Query: 394 NVLTTAYDMWSVGILMGIGLLGYTP------RIIGKRSRRLSVVFTSQEYLCISGAALHF 447
+ D+W+ G+++ I L+GY P + ++ + + F S E+ ++ A +
Sbjct: 189 DPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNL 248
Query: 448 FGKCLHTNPSRRLTAAQALNHPWM 471
+ L NP++R+TA QAL HPW+
Sbjct: 249 INQMLTINPAKRITADQALKHPWV 272
>U12779-1|AAA20851.1| 370|Homo sapiens MAP kinase activated protein
kinase 2 protein.
Length = 370
Score = 95.9 bits (228), Expect = 4e-19
Identities = 73/267 (27%), Positives = 124/267 (46%), Gaps = 20/267 (7%)
Query: 230 KLIGSGVYGKVMLIRSNAGKQFVAKTVISQYQTNSMEEYSTLRILRNTPNIVKLIECYSD 289
+++G G+ GKV+ I + ++ A ++ E R + P+IV++++ Y +
Sbjct: 68 QVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQ-CPHIVRIVDVYEN 126
Query: 290 ---GLNWVF-VMENLWGGNLFDRFKHH--QCISERDIKIYLRQVCSGLQYIHNNGLIHFD 343
G + VME L GG LF R + Q +ER+ ++ + +QY+H+ + H D
Sbjct: 127 LYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRD 186
Query: 344 IKPENVMCCSL--NCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLTTAYD 401
+KPEN++ S N + +K+ DFG K S + VAPE+ + D
Sbjct: 187 VKPENLLYTSKRPNAI-LKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCD 245
Query: 402 MWSVGILMGIGLLGYTPRI----------IGKRSRRLSVVFTSQEYLCISGAALHFFGKC 451
MWS+G++M I L GY P + R R F + E+ +S
Sbjct: 246 MWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNL 305
Query: 452 LHTNPSRRLTAAQALNHPWMFDTCPHP 478
L T P++R+T + +NHPW+ + P
Sbjct: 306 LKTEPTQRMTITEFMNHPWIMQSTKVP 332
>BC114478-1|AAI14479.1| 795|Homo sapiens MARK1 protein protein.
Length = 795
Score = 95.9 bits (228), Expect = 4e-19
Identities = 75/251 (29%), Positives = 117/251 (46%), Gaps = 12/251 (4%)
Query: 230 KLIGSGVYGKVMLIRSNAGKQFVAKTVISQYQTN--SMEE-YSTLRILR--NTPNIVKLI 284
K IG G + KV L R + VA +I + Q N S+++ + +RI++ N PNIVKL
Sbjct: 64 KTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVKLF 123
Query: 285 ECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFDI 344
E VME GG +FD H + E++ + RQ+ S +QY H ++H D+
Sbjct: 124 EVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIVHRDL 183
Query: 345 KPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLT-TAYDMW 403
K EN++ +NIKI DFG + ++ G APEL+ G D+W
Sbjct: 184 KAENLLLD--GDMNIKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVW 241
Query: 404 SVGILMGIGLLGYTPRIIGKRSRRLSVVFTSQEY---LCISGAALHFFGKCLHTNPSRRL 460
S+G+++ + G P G+ + L +Y +S + K L NP +R
Sbjct: 242 SLGVILYTLVSGSLP-FDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKLLVLNPIKRG 300
Query: 461 TAAQALNHPWM 471
+ Q + WM
Sbjct: 301 SLEQIMKDRWM 311
>BC113869-1|AAI13870.1| 795|Homo sapiens MARK1 protein protein.
Length = 795
Score = 95.9 bits (228), Expect = 4e-19
Identities = 75/251 (29%), Positives = 117/251 (46%), Gaps = 12/251 (4%)
Query: 230 KLIGSGVYGKVMLIRSNAGKQFVAKTVISQYQTN--SMEE-YSTLRILR--NTPNIVKLI 284
K IG G + KV L R + VA +I + Q N S+++ + +RI++ N PNIVKL
Sbjct: 64 KTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVKLF 123
Query: 285 ECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFDI 344
E VME GG +FD H + E++ + RQ+ S +QY H ++H D+
Sbjct: 124 EVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIVHRDL 183
Query: 345 KPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLT-TAYDMW 403
K EN++ +NIKI DFG + ++ G APEL+ G D+W
Sbjct: 184 KAENLLLD--GDMNIKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVW 241
Query: 404 SVGILMGIGLLGYTPRIIGKRSRRLSVVFTSQEY---LCISGAALHFFGKCLHTNPSRRL 460
S+G+++ + G P G+ + L +Y +S + K L NP +R
Sbjct: 242 SLGVILYTLVSGSLP-FDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKLLVLNPIKRG 300
Query: 461 TAAQALNHPWM 471
+ Q + WM
Sbjct: 301 SLEQIMKDRWM 311
>BC052584-1|AAH52584.1| 400|Homo sapiens mitogen-activated protein
kinase-activated protein kinase 2 protein.
Length = 400
Score = 95.9 bits (228), Expect = 4e-19
Identities = 73/267 (27%), Positives = 124/267 (46%), Gaps = 20/267 (7%)
Query: 230 KLIGSGVYGKVMLIRSNAGKQFVAKTVISQYQTNSMEEYSTLRILRNTPNIVKLIECYSD 289
+++G G+ GKV+ I + ++ A ++ E R + P+IV++++ Y +
Sbjct: 68 QVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQ-CPHIVRIVDVYEN 126
Query: 290 ---GLNWVF-VMENLWGGNLFDRFKHH--QCISERDIKIYLRQVCSGLQYIHNNGLIHFD 343
G + VME L GG LF R + Q +ER+ ++ + +QY+H+ + H D
Sbjct: 127 LYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRD 186
Query: 344 IKPENVMCCSL--NCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLTTAYD 401
+KPEN++ S N + +K+ DFG K S + VAPE+ + D
Sbjct: 187 VKPENLLYTSKRPNAI-LKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCD 245
Query: 402 MWSVGILMGIGLLGYTPRI----------IGKRSRRLSVVFTSQEYLCISGAALHFFGKC 451
MWS+G++M I L GY P + R R F + E+ +S
Sbjct: 246 MWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNL 305
Query: 452 LHTNPSRRLTAAQALNHPWMFDTCPHP 478
L T P++R+T + +NHPW+ + P
Sbjct: 306 LKTEPTQRMTITEFMNHPWIMQSTKVP 332
>BC037303-1|AAH37303.1| 550|Homo sapiens PRKAA1 protein protein.
Length = 550
Score = 95.9 bits (228), Expect = 4e-19
Identities = 70/266 (26%), Positives = 125/266 (46%), Gaps = 17/266 (6%)
Query: 232 IGSGVYGKVMLIRSNAGKQFVAKTVISQYQTNSME-------EYSTLRILRNTPNIVKLI 284
+G G +GKV + + VA ++++ + S++ E L++ R+ P+I+KL
Sbjct: 24 LGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRH-PHIIKLY 82
Query: 285 ECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFDI 344
+ S + VME + GG LFD + + E++ + +Q+ SG+ Y H + ++H D+
Sbjct: 83 QVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHMVVHRDL 142
Query: 345 KPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLT-TAYDMW 403
KPENV+ + +N KI DFGL+ + + G + APE+ SG + D+W
Sbjct: 143 KPENVLLDA--HMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIW 200
Query: 404 SVGILMGIGLLGYTP----RIIGKRSRRLSVVFTSQEYLCISGAALHFFGKCLHTNPSRR 459
S G+++ L G P + + +F + +YL + + + L +P +R
Sbjct: 201 SSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYL--NPSVISLLKHMLQVDPMKR 258
Query: 460 LTAAQALNHPWMFDTCPHPLSWKKPS 485
T H W P L + PS
Sbjct: 259 ATIKDIREHEWFKQDLPKYLFPEDPS 284
>BC036060-1|AAH36060.2| 400|Homo sapiens mitogen-activated protein
kinase-activated protein kinase 2 protein.
Length = 400
Score = 95.9 bits (228), Expect = 4e-19
Identities = 73/267 (27%), Positives = 124/267 (46%), Gaps = 20/267 (7%)
Query: 230 KLIGSGVYGKVMLIRSNAGKQFVAKTVISQYQTNSMEEYSTLRILRNTPNIVKLIECYSD 289
+++G G+ GKV+ I + ++ A ++ E R + P+IV++++ Y +
Sbjct: 68 QVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQ-CPHIVRIVDVYEN 126
Query: 290 ---GLNWVF-VMENLWGGNLFDRFKHH--QCISERDIKIYLRQVCSGLQYIHNNGLIHFD 343
G + VME L GG LF R + Q +ER+ ++ + +QY+H+ + H D
Sbjct: 127 LYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRD 186
Query: 344 IKPENVMCCSL--NCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLTTAYD 401
+KPEN++ S N + +K+ DFG K S + VAPE+ + D
Sbjct: 187 VKPENLLYTSKRPNAI-LKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCD 245
Query: 402 MWSVGILMGIGLLGYTPRI----------IGKRSRRLSVVFTSQEYLCISGAALHFFGKC 451
MWS+G++M I L GY P + R R F + E+ +S
Sbjct: 246 MWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNL 305
Query: 452 LHTNPSRRLTAAQALNHPWMFDTCPHP 478
L T P++R+T + +NHPW+ + P
Sbjct: 306 LKTEPTQRMTITEFMNHPWIMQSTKVP 332
>AL592406-3|CAH72463.1| 795|Homo sapiens MAP/microtubule
affinity-regulating kinase 1 protein.
Length = 795
Score = 95.9 bits (228), Expect = 4e-19
Identities = 75/251 (29%), Positives = 117/251 (46%), Gaps = 12/251 (4%)
Query: 230 KLIGSGVYGKVMLIRSNAGKQFVAKTVISQYQTN--SMEE-YSTLRILR--NTPNIVKLI 284
K IG G + KV L R + VA +I + Q N S+++ + +RI++ N PNIVKL
Sbjct: 64 KTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVKLF 123
Query: 285 ECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFDI 344
E VME GG +FD H + E++ + RQ+ S +QY H ++H D+
Sbjct: 124 EVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIVHRDL 183
Query: 345 KPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLT-TAYDMW 403
K EN++ +NIKI DFG + ++ G APEL+ G D+W
Sbjct: 184 KAENLLLD--GDMNIKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVW 241
Query: 404 SVGILMGIGLLGYTPRIIGKRSRRLSVVFTSQEY---LCISGAALHFFGKCLHTNPSRRL 460
S+G+++ + G P G+ + L +Y +S + K L NP +R
Sbjct: 242 SLGVILYTLVSGSLP-FDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKLLVLNPIKRG 300
Query: 461 TAAQALNHPWM 471
+ Q + WM
Sbjct: 301 SLEQIMKDRWM 311
>AL591846-12|CAI13544.1| 400|Homo sapiens mitogen-activated protein
kinase-activated protein kinase 2 protein.
Length = 400
Score = 95.9 bits (228), Expect = 4e-19
Identities = 73/267 (27%), Positives = 124/267 (46%), Gaps = 20/267 (7%)
Query: 230 KLIGSGVYGKVMLIRSNAGKQFVAKTVISQYQTNSMEEYSTLRILRNTPNIVKLIECYSD 289
+++G G+ GKV+ I + ++ A ++ E R + P+IV++++ Y +
Sbjct: 68 QVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQ-CPHIVRIVDVYEN 126
Query: 290 ---GLNWVF-VMENLWGGNLFDRFKHH--QCISERDIKIYLRQVCSGLQYIHNNGLIHFD 343
G + VME L GG LF R + Q +ER+ ++ + +QY+H+ + H D
Sbjct: 127 LYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRD 186
Query: 344 IKPENVMCCSL--NCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLTTAYD 401
+KPEN++ S N + +K+ DFG K S + VAPE+ + D
Sbjct: 187 VKPENLLYTSKRPNAI-LKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCD 245
Query: 402 MWSVGILMGIGLLGYTPRI----------IGKRSRRLSVVFTSQEYLCISGAALHFFGKC 451
MWS+G++M I L GY P + R R F + E+ +S
Sbjct: 246 MWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNL 305
Query: 452 LHTNPSRRLTAAQALNHPWMFDTCPHP 478
L T P++R+T + +NHPW+ + P
Sbjct: 306 LKTEPTQRMTITEFMNHPWIMQSTKVP 332
>AL591846-11|CAI13543.1| 370|Homo sapiens mitogen-activated protein
kinase-activated protein kinase 2 protein.
Length = 370
Score = 95.9 bits (228), Expect = 4e-19
Identities = 73/267 (27%), Positives = 124/267 (46%), Gaps = 20/267 (7%)
Query: 230 KLIGSGVYGKVMLIRSNAGKQFVAKTVISQYQTNSMEEYSTLRILRNTPNIVKLIECYSD 289
+++G G+ GKV+ I + ++ A ++ E R + P+IV++++ Y +
Sbjct: 68 QVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQ-CPHIVRIVDVYEN 126
Query: 290 ---GLNWVF-VMENLWGGNLFDRFKHH--QCISERDIKIYLRQVCSGLQYIHNNGLIHFD 343
G + VME L GG LF R + Q +ER+ ++ + +QY+H+ + H D
Sbjct: 127 LYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRD 186
Query: 344 IKPENVMCCSL--NCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLTTAYD 401
+KPEN++ S N + +K+ DFG K S + VAPE+ + D
Sbjct: 187 VKPENLLYTSKRPNAI-LKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCD 245
Query: 402 MWSVGILMGIGLLGYTPRI----------IGKRSRRLSVVFTSQEYLCISGAALHFFGKC 451
MWS+G++M I L GY P + R R F + E+ +S
Sbjct: 246 MWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNL 305
Query: 452 LHTNPSRRLTAAQALNHPWMFDTCPHP 478
L T P++R+T + +NHPW+ + P
Sbjct: 306 LKTEPTQRMTITEFMNHPWIMQSTKVP 332
>AF154845-1|AAF72103.1| 795|Homo sapiens MARK protein.
Length = 795
Score = 95.9 bits (228), Expect = 4e-19
Identities = 75/251 (29%), Positives = 117/251 (46%), Gaps = 12/251 (4%)
Query: 230 KLIGSGVYGKVMLIRSNAGKQFVAKTVISQYQTN--SMEE-YSTLRILR--NTPNIVKLI 284
K IG G + KV L R + VA +I + Q N S+++ + +RI++ N PNIVKL
Sbjct: 64 KTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVKLF 123
Query: 285 ECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFDI 344
E VME GG +FD H + E++ + RQ+ S +QY H ++H D+
Sbjct: 124 EVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIVHRDL 183
Query: 345 KPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLT-TAYDMW 403
K EN++ +NIKI DFG + ++ G APEL+ G D+W
Sbjct: 184 KAENLLLD--GDMNIKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVW 241
Query: 404 SVGILMGIGLLGYTPRIIGKRSRRLSVVFTSQEY---LCISGAALHFFGKCLHTNPSRRL 460
S+G+++ + G P G+ + L +Y +S + K L NP +R
Sbjct: 242 SLGVILYTLVSGSLP-FDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKLLVLNPIKRG 300
Query: 461 TAAQALNHPWM 471
+ Q + WM
Sbjct: 301 SLEQIMKDRWM 311
>BC017306-1|AAH17306.1| 628|Homo sapiens NUAK family, SNF1-like
kinase, 2 protein.
Length = 628
Score = 95.5 bits (227), Expect = 6e-19
Identities = 71/251 (28%), Positives = 116/251 (46%), Gaps = 11/251 (4%)
Query: 229 LKLIGSGVYGKVMLIRSNAGKQFVAKTVISQY---QTNSMEEYSTLRILR--NTPNIVKL 283
L+ +G G YGKV R ++G+ K++ + + M + I+ N P+I+ +
Sbjct: 56 LETLGKGTYGKVKKARESSGRLVAIKSIRKDKIKDEQDLMHIRREIEIMSSLNHPHIIAI 115
Query: 284 IECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFD 343
E + + V VME G+L+D Q +SER+ + + RQ+ S + Y H N ++H D
Sbjct: 116 HEVFENSSKIVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSAVHYCHQNRVVHRD 175
Query: 344 IKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLT-TAYDM 402
+K EN++ + NIKI DFGL+ + G +PE+ +G T D
Sbjct: 176 LKLENILLDANG--NIKIADFGLSNLYHQGKFLQTFCGSPLYASPEIVNGKPYTGPEVDS 233
Query: 403 WSVGILMGIGLLGYTPRIIGKRSRRLSVVFTSQEYL--CISGAALHFFGKCLHTNPSRRL 460
WS+G+L+ I + G P G + L ++ Y A L NP+RR
Sbjct: 234 WSLGVLLYILVHGTMP-FDGHDHKILVKQISNGAYREPPKPSDACGLIRWLLMVNPTRRA 292
Query: 461 TAAQALNHPWM 471
T +H W+
Sbjct: 293 TLEDVASHWWV 303
>AK074830-1|BAC11234.1| 628|Homo sapiens protein ( Homo sapiens
cDNA FLJ90349 fis, clone NT2RP2003179, weakly similar to
PUTATIVE SERINE/THREONINE-PROTEIN KINASE EMK (EC
2.7.1.-). ).
Length = 628
Score = 95.5 bits (227), Expect = 6e-19
Identities = 71/251 (28%), Positives = 116/251 (46%), Gaps = 11/251 (4%)
Query: 229 LKLIGSGVYGKVMLIRSNAGKQFVAKTVISQY---QTNSMEEYSTLRILR--NTPNIVKL 283
L+ +G G YGKV R ++G+ K++ + + M + I+ N P+I+ +
Sbjct: 56 LETLGKGTYGKVKKARESSGRLVAIKSIRKDKIKDEQDLMHIRREIEIMSSLNHPHIIAI 115
Query: 284 IECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFD 343
E + + V VME G+L+D Q +SER+ + + RQ+ S + Y H N ++H D
Sbjct: 116 HEVFENSSKIVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSAVHYCHQNRVVHRD 175
Query: 344 IKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLT-TAYDM 402
+K EN++ + NIKI DFGL+ + G +PE+ +G T D
Sbjct: 176 LKLENILLDANG--NIKIADFGLSNLYHQGKFLQTFCGSPLYASPEIVNGKPYTGPEVDS 233
Query: 403 WSVGILMGIGLLGYTPRIIGKRSRRLSVVFTSQEYL--CISGAALHFFGKCLHTNPSRRL 460
WS+G+L+ I + G P G + L ++ Y A L NP+RR
Sbjct: 234 WSLGVLLYILVHGTMP-FDGHDHKILVKQISNGAYREPPKPSDACGLIRWLLMVNPTRRA 292
Query: 461 TAAQALNHPWM 471
T +H W+
Sbjct: 293 TLEDVASHWWV 303
>AJ271722-1|CAB71146.1| 714|Homo sapiens putative serine/threonine
protein kinase MAK-V protein.
Length = 714
Score = 95.5 bits (227), Expect = 6e-19
Identities = 64/220 (29%), Positives = 106/220 (48%), Gaps = 10/220 (4%)
Query: 260 YQTNSMEEYSTLRILRNTPNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERD 319
Y T ++ ++ + PNI +L++ ++ VME GGNL + + + E +
Sbjct: 103 YVTKNLRREGQIQQMIRHPNITQLLDILETENSYYLVMELCPGGNLMHKIYEKKRLEESE 162
Query: 320 IKIYLRQVCSGLQYIHNNGLIHFDIKPENVMCCSLNCLNIKIIDFGLTKCA---RSRTPI 376
+ Y+RQ+ S ++++H G++H D+K EN++ N NIK+IDFGL+ CA P
Sbjct: 163 ARRYIRQLISAVEHLHRAGVVHRDLKIENLLLDEDN--NIKLIDFGLSNCAGILGYSDPF 220
Query: 377 NRNFGFFSSVAPELYSGNVLTTAYDMWSVGILMGIGLLGYTPRIIGKRS-RRLSVVFTSQ 435
+ G + APEL + D+WS+G+ M L G P + S R L +
Sbjct: 221 STQCGSPAYAAPELLARKKYGPKIDVWSIGVNMYAMLTGTLPFTVEPFSLRALYQKMVDK 280
Query: 436 EY----LCISGAALHFFGKCLHTNPSRRLTAAQALNHPWM 471
E +S A+ F L +P +R QAL + W+
Sbjct: 281 EMNPLPTQLSTGAISFLRSLLEPDPVKRPNIQQALANRWL 320
>AB019245-1|BAA37145.1| 481|Homo sapiens S6 kinase b protein.
Length = 481
Score = 95.1 bits (226), Expect = 8e-19
Identities = 75/259 (28%), Positives = 116/259 (44%), Gaps = 19/259 (7%)
Query: 229 LKLIGSGVYGKVMLIRS---NAGKQFVAKTVISQYQTNSMEEYSTLRILRNT------PN 279
L+++G G YGKV +R N GK + K + + ++ + R RN P
Sbjct: 70 LRVLGKGGYGKVFQVRKVQGNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNILESVKHPF 129
Query: 280 IVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGL 339
IV+L + G ++E L GG LF + E YL ++ L ++H+ G+
Sbjct: 130 IVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITLALGHLHSQGI 189
Query: 340 IHFDIKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNF-GFFSSVAPELYSGNVLTT 398
I+ D+KPEN+M S +IK+ DFGL K + + F G +APE+ +
Sbjct: 190 IYRDLKPENIMLSSQG--HIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEILVRSGHNR 247
Query: 399 AYDMWSVGILMGIGLLGYTPRIIGKRSRRLSVVFTSQEYL--CISGAALHFFGKCLHTNP 456
A D WS+G LM L G P R + + + + L ++ A K L NP
Sbjct: 248 AVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLALPPYLTPDARDLVKKFLKRNP 307
Query: 457 SRRL-----TAAQALNHPW 470
S+R+ AA HP+
Sbjct: 308 SQRIGGGPGDAADVQRHPF 326
>U64205-1|AAC15093.1| 729|Homo sapiens Cdc25C associated protein
kinase C-TAK1 protein.
Length = 729
Score = 94.7 bits (225), Expect = 1e-18
Identities = 74/252 (29%), Positives = 119/252 (47%), Gaps = 12/252 (4%)
Query: 229 LKLIGSGVYGKVMLIRSNAGKQFVAKTVISQYQTN--SMEE-YSTLRILR--NTPNIVKL 283
LK IG G + KV L R + VA +I + Q N S+++ + +RI++ N PNIVKL
Sbjct: 59 LKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVKL 118
Query: 284 IECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFD 343
E +ME GG +FD H + E++ + RQ+ S +QY H ++H D
Sbjct: 119 FEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIVHRD 178
Query: 344 IKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLT-TAYDM 402
+K EN++ + +NIKI DFG + ++ G APEL+ G D+
Sbjct: 179 LKAENLLLDA--DMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEVDV 236
Query: 403 WSVGILMGIGLLGYTPRIIGKRSRRLSVVFTSQEY---LCISGAALHFFGKCLHTNPSRR 459
WS+G+++ + G P G+ + L +Y +S + + L NP +R
Sbjct: 237 WSLGVILYTLVSGSLP-FDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPIKR 295
Query: 460 LTAAQALNHPWM 471
T Q + W+
Sbjct: 296 GTLEQIMKDRWI 307
>M80359-1|AAA59991.1| 713|Homo sapiens protein p78 protein.
Length = 713
Score = 94.7 bits (225), Expect = 1e-18
Identities = 74/252 (29%), Positives = 119/252 (47%), Gaps = 12/252 (4%)
Query: 229 LKLIGSGVYGKVMLIRSNAGKQFVAKTVISQYQTN--SMEE-YSTLRILR--NTPNIVKL 283
LK IG G + KV L R + VA +I + Q N S+++ + +RI++ N PNIVKL
Sbjct: 59 LKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVKL 118
Query: 284 IECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFD 343
E +ME GG +FD H + E++ + RQ+ S +QY H ++H D
Sbjct: 119 FEVIETQKTLYLIMEYASGGKVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIVHRD 178
Query: 344 IKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLT-TAYDM 402
+K EN++ + +NIKI DFG + ++ G APEL+ G D+
Sbjct: 179 LKAENLLLDA--DMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEVDV 236
Query: 403 WSVGILMGIGLLGYTPRIIGKRSRRLSVVFTSQEY---LCISGAALHFFGKCLHTNPSRR 459
WS+G+++ + G P G+ + L +Y +S + + L NP +R
Sbjct: 237 WSLGVILYTLVSGSLP-FDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPIKR 295
Query: 460 LTAAQALNHPWM 471
T Q + W+
Sbjct: 296 GTLEQIMKDRWI 307
>BC024773-1|AAH24773.1| 729|Homo sapiens MAP/microtubule
affinity-regulating kinase 3 protein.
Length = 729
Score = 94.7 bits (225), Expect = 1e-18
Identities = 74/252 (29%), Positives = 119/252 (47%), Gaps = 12/252 (4%)
Query: 229 LKLIGSGVYGKVMLIRSNAGKQFVAKTVISQYQTN--SMEE-YSTLRILR--NTPNIVKL 283
LK IG G + KV L R + VA +I + Q N S+++ + +RI++ N PNIVKL
Sbjct: 59 LKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVKL 118
Query: 284 IECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFD 343
E +ME GG +FD H + E++ + RQ+ S +QY H ++H D
Sbjct: 119 FEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIVHRD 178
Query: 344 IKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLT-TAYDM 402
+K EN++ + +NIKI DFG + ++ G APEL+ G D+
Sbjct: 179 LKAENLLLDA--DMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEVDV 236
Query: 403 WSVGILMGIGLLGYTPRIIGKRSRRLSVVFTSQEY---LCISGAALHFFGKCLHTNPSRR 459
WS+G+++ + G P G+ + L +Y +S + + L NP +R
Sbjct: 237 WSLGVILYTLVSGSLP-FDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPIKR 295
Query: 460 LTAAQALNHPWM 471
T Q + W+
Sbjct: 296 GTLEQIMKDRWI 307
>BC006106-1|AAH06106.3| 482|Homo sapiens ribosomal protein S6
kinase, 70kDa, polypeptide 2 protein.
Length = 482
Score = 94.7 bits (225), Expect = 1e-18
Identities = 75/260 (28%), Positives = 117/260 (45%), Gaps = 20/260 (7%)
Query: 229 LKLIGSGVYGKVMLIR----SNAGKQFVAKTVISQYQTNSMEEYSTLRILRNT------P 278
L+++G G YGKV +R +N GK + K + + ++ + R RN P
Sbjct: 70 LRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNILESVKHP 129
Query: 279 NIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNG 338
IV+L + G ++E L GG LF + E YL ++ L ++H+ G
Sbjct: 130 FIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITLALGHLHSQG 189
Query: 339 LIHFDIKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNF-GFFSSVAPELYSGNVLT 397
+I+ D+KPEN+M S +IK+ DFGL K + + F G +APE+ +
Sbjct: 190 IIYRDLKPENIMLSSQG--HIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEILVRSGHN 247
Query: 398 TAYDMWSVGILMGIGLLGYTPRIIGKRSRRLSVVFTSQEYL--CISGAALHFFGKCLHTN 455
A D WS+G LM L G P R + + + + L ++ A K L N
Sbjct: 248 RAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLALPPYLTPDARDLVKKFLKRN 307
Query: 456 PSRRL-----TAAQALNHPW 470
PS+R+ AA HP+
Sbjct: 308 PSQRIGGGPGDAADVQRHPF 327
>BC000094-1|AAH00094.3| 482|Homo sapiens ribosomal protein S6
kinase, 70kDa, polypeptide 2 protein.
Length = 482
Score = 94.7 bits (225), Expect = 1e-18
Identities = 75/260 (28%), Positives = 117/260 (45%), Gaps = 20/260 (7%)
Query: 229 LKLIGSGVYGKVMLIR----SNAGKQFVAKTVISQYQTNSMEEYSTLRILRNT------P 278
L+++G G YGKV +R +N GK + K + + ++ + R RN P
Sbjct: 70 LRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNILESVKHP 129
Query: 279 NIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNG 338
IV+L + G ++E L GG LF + E YL ++ L ++H+ G
Sbjct: 130 FIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITLALGHLHSQG 189
Query: 339 LIHFDIKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNF-GFFSSVAPELYSGNVLT 397
+I+ D+KPEN+M S +IK+ DFGL K + + F G +APE+ +
Sbjct: 190 IIYRDLKPENIMLSSQG--HIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEILVRSGHN 247
Query: 398 TAYDMWSVGILMGIGLLGYTPRIIGKRSRRLSVVFTSQEYL--CISGAALHFFGKCLHTN 455
A D WS+G LM L G P R + + + + L ++ A K L N
Sbjct: 248 RAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLALPPYLTPDARDLVKKFLKRN 307
Query: 456 PSRRL-----TAAQALNHPW 470
PS+R+ AA HP+
Sbjct: 308 PSQRIGGGPGDAADVQRHPF 327
>AF465413-1|AAL69982.1| 753|Homo sapiens MAP/microtubule
affinity-regulating kinase 3 long isoform protein.
Length = 753
Score = 94.7 bits (225), Expect = 1e-18
Identities = 74/252 (29%), Positives = 119/252 (47%), Gaps = 12/252 (4%)
Query: 229 LKLIGSGVYGKVMLIRSNAGKQFVAKTVISQYQTN--SMEE-YSTLRILR--NTPNIVKL 283
LK IG G + KV L R + VA +I + Q N S+++ + +RI++ N PNIVKL
Sbjct: 59 LKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVKL 118
Query: 284 IECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFD 343
E +ME GG +FD H + E++ + RQ+ S +QY H ++H D
Sbjct: 119 FEVIETEKTLYLIMEYASGGKVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIVHRD 178
Query: 344 IKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLT-TAYDM 402
+K EN++ + +NIKI DFG + ++ G APEL+ G D+
Sbjct: 179 LKAENLLLDA--DMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEVDV 236
Query: 403 WSVGILMGIGLLGYTPRIIGKRSRRLSVVFTSQEY---LCISGAALHFFGKCLHTNPSRR 459
WS+G+++ + G P G+ + L +Y +S + + L NP +R
Sbjct: 237 WSLGVILYTLVSGSLP-FDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPIKR 295
Query: 460 LTAAQALNHPWM 471
T Q + W+
Sbjct: 296 GTLEQIMKDRWI 307
>AF387637-1|AAK82367.1| 744|Homo sapiens Ser/Thr protein kinase
PAR-1A protein.
Length = 744
Score = 94.7 bits (225), Expect = 1e-18
Identities = 74/252 (29%), Positives = 119/252 (47%), Gaps = 12/252 (4%)
Query: 229 LKLIGSGVYGKVMLIRSNAGKQFVAKTVISQYQTN--SMEE-YSTLRILR--NTPNIVKL 283
LK IG G + KV L R + VA +I + Q N S+++ + +RI++ N PNIVKL
Sbjct: 59 LKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVKL 118
Query: 284 IECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFD 343
E +ME GG +FD H + E++ + RQ+ S +QY H ++H D
Sbjct: 119 FEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIVHRD 178
Query: 344 IKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLT-TAYDM 402
+K EN++ + +NIKI DFG + ++ G APEL+ G D+
Sbjct: 179 LKAENLLLDA--DMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEVDV 236
Query: 403 WSVGILMGIGLLGYTPRIIGKRSRRLSVVFTSQEY---LCISGAALHFFGKCLHTNPSRR 459
WS+G+++ + G P G+ + L +Y +S + + L NP +R
Sbjct: 237 WSLGVILYTLVSGSLP-FDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPIKR 295
Query: 460 LTAAQALNHPWM 471
T Q + W+
Sbjct: 296 GTLEQIMKDRWI 307
>AF099739-1|AAD20990.1| 482|Homo sapiens S6 kinase-related kinase
protein.
Length = 482
Score = 94.7 bits (225), Expect = 1e-18
Identities = 75/260 (28%), Positives = 117/260 (45%), Gaps = 20/260 (7%)
Query: 229 LKLIGSGVYGKVMLIR----SNAGKQFVAKTVISQYQTNSMEEYSTLRILRNT------P 278
L+++G G YGKV +R +N GK + K + + ++ + R RN P
Sbjct: 70 LRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNILESVKHP 129
Query: 279 NIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNG 338
IV+L + G ++E L GG LF + E YL ++ L ++H+ G
Sbjct: 130 FIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITLALGHLHSQG 189
Query: 339 LIHFDIKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNF-GFFSSVAPELYSGNVLT 397
+I+ D+KPEN+M S +IK+ DFGL K + + F G +APE+ +
Sbjct: 190 IIYRDLKPENIMLSSQG--HIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEILVRSGHN 247
Query: 398 TAYDMWSVGILMGIGLLGYTPRIIGKRSRRLSVVFTSQEYL--CISGAALHFFGKCLHTN 455
A D WS+G LM L G P R + + + + L ++ A K L N
Sbjct: 248 RAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLALPPYLTPDARDLVKKFLKRN 307
Query: 456 PSRRL-----TAAQALNHPW 470
PS+R+ AA HP+
Sbjct: 308 PSQRIGGGPGDAADVQRHPF 327
>AF076931-1|AAD46063.1| 482|Homo sapiens serine/threonine kinase 14
beta protein.
Length = 482
Score = 94.7 bits (225), Expect = 1e-18
Identities = 75/260 (28%), Positives = 117/260 (45%), Gaps = 20/260 (7%)
Query: 229 LKLIGSGVYGKVMLIR----SNAGKQFVAKTVISQYQTNSMEEYSTLRILRNT------P 278
L+++G G YGKV +R +N GK + K + + ++ + R RN P
Sbjct: 70 LRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNILESVKHP 129
Query: 279 NIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNG 338
IV+L + G ++E L GG LF + E YL ++ L ++H+ G
Sbjct: 130 FIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITLALGHLHSQG 189
Query: 339 LIHFDIKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNF-GFFSSVAPELYSGNVLT 397
+I+ D+KPEN+M S +IK+ DFGL K + + F G +APE+ +
Sbjct: 190 IIYRDLKPENIMLSSQG--HIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEILVRSGHN 247
Query: 398 TAYDMWSVGILMGIGLLGYTPRIIGKRSRRLSVVFTSQEYL--CISGAALHFFGKCLHTN 455
A D WS+G LM L G P R + + + + L ++ A K L N
Sbjct: 248 RAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLALPPYLTPDARDLVKKFLKRN 307
Query: 456 PSRRL-----TAAQALNHPW 470
PS+R+ AA HP+
Sbjct: 308 PSQRIGGGPGDAADVQRHPF 327
>AB016869-1|BAA34402.1| 495|Homo sapiens p70 ribosomal S6 kinase
beta protein.
Length = 495
Score = 94.7 bits (225), Expect = 1e-18
Identities = 75/260 (28%), Positives = 117/260 (45%), Gaps = 20/260 (7%)
Query: 229 LKLIGSGVYGKVMLIR----SNAGKQFVAKTVISQYQTNSMEEYSTLRILRNT------P 278
L+++G G YGKV +R +N GK + K + + ++ + R RN P
Sbjct: 83 LRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNILESVKHP 142
Query: 279 NIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNG 338
IV+L + G ++E L GG LF + E YL ++ L ++H+ G
Sbjct: 143 FIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITLALGHLHSQG 202
Query: 339 LIHFDIKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNF-GFFSSVAPELYSGNVLT 397
+I+ D+KPEN+M S +IK+ DFGL K + + F G +APE+ +
Sbjct: 203 IIYRDLKPENIMLSSQG--HIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEILVRSGHN 260
Query: 398 TAYDMWSVGILMGIGLLGYTPRIIGKRSRRLSVVFTSQEYL--CISGAALHFFGKCLHTN 455
A D WS+G LM L G P R + + + + L ++ A K L N
Sbjct: 261 RAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLALPPYLTPDARDLVKKFLKRN 320
Query: 456 PSRRL-----TAAQALNHPW 470
PS+R+ AA HP+
Sbjct: 321 PSQRIGGGPGDAADVQRHPF 340
>AY603755-1|AAT80901.1| 3094|Homo sapiens striated muscle
preferentially expressed protein protein.
Length = 3094
Score = 94.3 bits (224), Expect = 1e-18
Identities = 74/244 (30%), Positives = 115/244 (47%), Gaps = 13/244 (5%)
Query: 235 GVYGKVMLIRSNA-GKQFVAKTV--ISQYQTNSMEEYSTLRILRNTPNIVKLIECYSDGL 291
G +G V R NA G+ FVAK V ++ + ++EY LR L + I+ L E Y
Sbjct: 2846 GRFGVVRACRENATGRTFVAKIVPYAAEGKPRVLQEYEVLRTLHHE-RIMSLHEAYITPR 2904
Query: 292 NWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFDIKPENVMC 351
V + E+ L SE D+ Y+ Q+ GL Y+H + ++H DIKP+N++
Sbjct: 2905 YLVLIAESCGNRELLCGLSDRFRYSEDDVATYMVQLLQGLDYLHGHHVLHLDIKPDNLLL 2964
Query: 352 CSLNCLNIKIIDFGLTK--CARSRTPINRNFGFFSSVAPELYSGNVLTTAYDMWSVGILM 409
N L KI+DFG + ++ P+ G +APE+ G + +A D+W G+L
Sbjct: 2965 APDNAL--KIVDFGSAQPYNPQALRPLGHRTGTLEFMAPEMVKGEPIGSATDIWGAGVLT 3022
Query: 410 GIGLLG----YTPRIIGKRSRRLSVVFTS-QEYLCISGAALHFFGKCLHTNPSRRLTAAQ 464
I L G Y P +R + F + Q Y S +A F K L +P R ++
Sbjct: 3023 YIMLSGRSPFYEPDPQETEARIVGGRFDAFQLYPNTSQSATLFLRKVLSVHPWSRPSSCL 3082
Query: 465 ALNH 468
++ H
Sbjct: 3083 SVCH 3086
Score = 91.5 bits (217), Expect = 9e-18
Identities = 63/249 (25%), Positives = 113/249 (45%), Gaps = 12/249 (4%)
Query: 232 IGSGVYGKVM-LIRSNAGKQFVAKTVISQYQTNSMEEYSTLRILRNTPNIVKLIECYSDG 290
IG G + + ++ ++G +F AK + SQ + + + R + V +
Sbjct: 1478 IGRGAFSYLRRIVERSSGLEFAAKFIPSQAKPKASARREARLLARLQHDCVLYFHEAFER 1537
Query: 291 LNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFDIKPENVM 350
+ ++ L L +R + E +I+ Y+RQV G+ Y+H + ++H D+KPEN++
Sbjct: 1538 RRGLVIVTELCTEELLERIARKPTVCESEIRAYMRQVLEGIHYLHQSHVLHLDVKPENLL 1597
Query: 351 CC--SLNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLTTAYDMWSVGIL 408
+ ++I DFG + P +G VAPE+ + + ++ D+W VG++
Sbjct: 1598 VWDGAAGEQQVRICDFGNAQELTPGEPQYCQYGTPEFVAPEIVNQSPVSGVTDIWPVGVV 1657
Query: 409 MGIGLLGYTPRIIGKRS-------RRLSVVFTSQEYLCISGAALHFFGKCLHTNPSRRLT 461
+ L G +P +G+ R +V F +L +S A F K L R T
Sbjct: 1658 AFLCLTGISP-FVGENDRTTLMNIRNYNVAFEETTFLSLSREARGFLIKVL-VQDRLRPT 1715
Query: 462 AAQALNHPW 470
A + L HPW
Sbjct: 1716 AEETLEHPW 1724
>AB037718-1|BAA92535.1| 2242|Homo sapiens KIAA1297 protein protein.
Length = 2242
Score = 94.3 bits (224), Expect = 1e-18
Identities = 74/244 (30%), Positives = 115/244 (47%), Gaps = 13/244 (5%)
Query: 235 GVYGKVMLIRSNA-GKQFVAKTV--ISQYQTNSMEEYSTLRILRNTPNIVKLIECYSDGL 291
G +G V R NA G+ FVAK V ++ + ++EY LR L + I+ L E Y
Sbjct: 1994 GRFGVVRACRENATGRTFVAKIVPYAAEGKPRVLQEYEVLRTLHHE-RIMSLHEAYITPR 2052
Query: 292 NWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFDIKPENVMC 351
V + E+ L SE D+ Y+ Q+ GL Y+H + ++H DIKP+N++
Sbjct: 2053 YLVLIAESCGNRELLCGLSDRFRYSEDDVATYMVQLLQGLDYLHGHHVLHLDIKPDNLLL 2112
Query: 352 CSLNCLNIKIIDFGLTK--CARSRTPINRNFGFFSSVAPELYSGNVLTTAYDMWSVGILM 409
N L KI+DFG + ++ P+ G +APE+ G + +A D+W G+L
Sbjct: 2113 APDNAL--KIVDFGSAQPYNPQALRPLGHRTGTLEFMAPEMVKGEPIGSATDIWGAGVLT 2170
Query: 410 GIGLLG----YTPRIIGKRSRRLSVVFTS-QEYLCISGAALHFFGKCLHTNPSRRLTAAQ 464
I L G Y P +R + F + Q Y S +A F K L +P R ++
Sbjct: 2171 YIMLSGRSPFYEPDPQETEARIVGGRFDAFQLYPNTSQSATLFLRKVLSVHPWSRPSSCL 2230
Query: 465 ALNH 468
++ H
Sbjct: 2231 SVCH 2234
Score = 91.5 bits (217), Expect = 9e-18
Identities = 63/249 (25%), Positives = 113/249 (45%), Gaps = 12/249 (4%)
Query: 232 IGSGVYGKVM-LIRSNAGKQFVAKTVISQYQTNSMEEYSTLRILRNTPNIVKLIECYSDG 290
IG G + + ++ ++G +F AK + SQ + + + R + V +
Sbjct: 626 IGRGAFSYLRRIVERSSGLEFAAKFIPSQAKPKASARREARLLARLQHDCVLYFHEAFER 685
Query: 291 LNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFDIKPENVM 350
+ ++ L L +R + E +I+ Y+RQV G+ Y+H + ++H D+KPEN++
Sbjct: 686 RRGLVIVTELCTEELLERIARKPTVCESEIRAYMRQVLEGIHYLHQSHVLHLDVKPENLL 745
Query: 351 CC--SLNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLTTAYDMWSVGIL 408
+ ++I DFG + P +G VAPE+ + + ++ D+W VG++
Sbjct: 746 VWDGAAGEQQVRICDFGNAQELTPGEPQYCQYGTPEFVAPEIVNQSPVSGVTDIWPVGVV 805
Query: 409 MGIGLLGYTPRIIGKRS-------RRLSVVFTSQEYLCISGAALHFFGKCLHTNPSRRLT 461
+ L G +P +G+ R +V F +L +S A F K L R T
Sbjct: 806 AFLCLTGISP-FVGENDRTTLMNIRNYNVAFEETTFLSLSREARGFLIKVL-VQDRLRPT 863
Query: 462 AAQALNHPW 470
A + L HPW
Sbjct: 864 AEETLEHPW 872
>AB022017-1|BAA36547.1| 550|Homo sapiens AMP-activated protein
kinase alpha-1 protein.
Length = 550
Score = 94.3 bits (224), Expect = 1e-18
Identities = 69/266 (25%), Positives = 125/266 (46%), Gaps = 17/266 (6%)
Query: 232 IGSGVYGKVMLIRSNAGKQFVAKTVISQYQTNSME-------EYSTLRILRNTPNIVKLI 284
+G G +GKV + + VA ++++ + S++ E L++ R+ P+I+KL
Sbjct: 24 LGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRH-PHIIKLY 82
Query: 285 ECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFDI 344
+ S + VME + GG LFD + + E++ + +Q+ SG+ Y H + ++H D+
Sbjct: 83 QVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHMVVHRDL 142
Query: 345 KPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLT-TAYDMW 403
KPENV+ + +N KI DFGL+ + + G + APE+ SG + D+W
Sbjct: 143 KPENVLLDA--HMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIW 200
Query: 404 SVGILMGIGLLGYTP----RIIGKRSRRLSVVFTSQEYLCISGAALHFFGKCLHTNPSRR 459
S G+++ L G P + + +F + +YL + + + L +P +R
Sbjct: 201 SSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYL--NPSVISLLKHMLQVDPMKR 258
Query: 460 LTAAQALNHPWMFDTCPHPLSWKKPS 485
+ H W P L + PS
Sbjct: 259 ASIKDIREHEWFKQDLPKYLFPEDPS 284
>D43636-1|BAA07744.2| 766|Homo sapiens KIAA0096 protein.
Length = 766
Score = 93.9 bits (223), Expect = 2e-18
Identities = 67/259 (25%), Positives = 123/259 (47%), Gaps = 12/259 (4%)
Query: 230 KLIGSGVYGKVMLIRSNAGKQFVAKTVISQYQTNSM------EEYSTLRILRNTPNIVKL 283
K +G G + V L R + VA VI + + +++ +E ++++++ PNIV+L
Sbjct: 21 KTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKLDTLATGHLFQEVRCMKLVQH-PNIVRL 79
Query: 284 IECYSDGLNWVFVMENLWGGNLFDRF-KHHQCISERDIKIYLRQVCSGLQYIHNNGLIHF 342
E ++E GG++FD KH + ++E K Y Q+ + Y H ++H
Sbjct: 80 YEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAISYCHKLHVVHR 139
Query: 343 DIKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVL-TTAYD 401
D+KPENV+ L +K+ DFG + + + + G + APE+ G+ A D
Sbjct: 140 DLKPENVVFFEKQGL-VKLTDFGFSNKFQPGKKLTTSCGSLAYSAPEILLGDEYDAPAVD 198
Query: 402 MWSVGILMGIGLLGYTPRIIGKRSRRLSVVFTSQEYL--CISGAALHFFGKCLHTNPSRR 459
+WS+G+++ + + G P S L+++ + + +S + L +P RR
Sbjct: 199 IWSLGVILFMLVCGQPPFQEANDSETLTMIMDCKYTVPSHVSKECKDLITRMLQRDPKRR 258
Query: 460 LTAAQALNHPWMFDTCPHP 478
+ + NHPW+ P P
Sbjct: 259 ASLEEIENHPWLQGVDPSP 277
>AF415197-1|AAM33514.1| 566|Homo sapiens
calcium/calmodulin-dependent protein kinase II gamma
protein.
Length = 566
Score = 93.9 bits (223), Expect = 2e-18
Identities = 63/242 (26%), Positives = 118/242 (48%), Gaps = 14/242 (5%)
Query: 243 IRSNAGKQFVAKTV----ISQYQTNSMEEYSTLRILRNTPNIVKLIECYSDGLNWVFVME 298
++ + +++ AK + +S +E + + L PNIV+L + S+ V +
Sbjct: 10 VKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFD 69
Query: 299 NLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFDIKPENVMCCSLNCLN 358
+ GG LF+ + SE D + Q+ + +IH + ++H D+KPEN++ S C
Sbjct: 70 LVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHDIVHRDLKPENLLLAS-KCKG 128
Query: 359 --IKIIDFGLTKCARSRTPINRNF-GFFSSVAPELYSGNVLTTAYDMWSVGILMGIGLLG 415
+K+ DFGL + F G ++PE+ + D+W+ G+++ I L+G
Sbjct: 129 AAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDIWACGVILYILLVG 188
Query: 416 YTP------RIIGKRSRRLSVVFTSQEYLCISGAALHFFGKCLHTNPSRRLTAAQALNHP 469
Y P + ++ + + F S E+ ++ A + + L NP++R+TA QAL HP
Sbjct: 189 YPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITADQALKHP 248
Query: 470 WM 471
W+
Sbjct: 249 WV 250
>BC020479-1|AAH20479.1| 466|Homo sapiens AKT3 protein protein.
Length = 466
Score = 93.1 bits (221), Expect = 3e-18
Identities = 64/201 (31%), Positives = 101/201 (50%), Gaps = 9/201 (4%)
Query: 225 DFLPLKLIGSGVYGKVMLIRSNAGKQFVAKTVISQYQTNSMEEYS-TL---RILRNT--P 278
DF LKL+G G +GKV+L+R A ++ A ++ + + +E + TL R+L+NT P
Sbjct: 147 DFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHP 206
Query: 279 NIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNG 338
+ L + FVME + GG LF + SE + Y ++ S L Y+H+
Sbjct: 207 FLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSGK 266
Query: 339 LIHFDIKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNF-GFFSSVAPELYSGNVLT 397
+++ D+K EN+M +IKI DFGL K + + F G +APE+ N
Sbjct: 267 IVYRDLKLENLMLDKDG--HIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDYG 324
Query: 398 TAYDMWSVGILMGIGLLGYTP 418
A D W +G++M + G P
Sbjct: 325 RAVDWWGLGVVMYEMMCGRLP 345
>AY005799-1|AAF91073.1| 465|Homo sapiens protein kinase B gamma 1
protein.
Length = 465
Score = 93.1 bits (221), Expect = 3e-18
Identities = 64/201 (31%), Positives = 101/201 (50%), Gaps = 9/201 (4%)
Query: 225 DFLPLKLIGSGVYGKVMLIRSNAGKQFVAKTVISQYQTNSMEEYS-TL---RILRNT--P 278
DF LKL+G G +GKV+L+R A ++ A ++ + + +E + TL R+L+NT P
Sbjct: 147 DFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHP 206
Query: 279 NIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNG 338
+ L + FVME + GG LF + SE + Y ++ S L Y+H+
Sbjct: 207 FLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSGK 266
Query: 339 LIHFDIKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNF-GFFSSVAPELYSGNVLT 397
+++ D+K EN+M +IKI DFGL K + + F G +APE+ N
Sbjct: 267 IVYRDLKLENLMLDKDG--HIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDYG 324
Query: 398 TAYDMWSVGILMGIGLLGYTP 418
A D W +G++M + G P
Sbjct: 325 RAVDWWGLGVVMYEMMCGRLP 345
>AL662889-3|CAH73073.1| 479|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 479
Score = 93.1 bits (221), Expect = 3e-18
Identities = 64/201 (31%), Positives = 101/201 (50%), Gaps = 9/201 (4%)
Query: 225 DFLPLKLIGSGVYGKVMLIRSNAGKQFVAKTVISQYQTNSMEEYS-TL---RILRNT--P 278
DF LKL+G G +GKV+L+R A ++ A ++ + + +E + TL R+L+NT P
Sbjct: 147 DFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHP 206
Query: 279 NIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNG 338
+ L + FVME + GG LF + SE + Y ++ S L Y+H+
Sbjct: 207 FLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSGK 266
Query: 339 LIHFDIKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNF-GFFSSVAPELYSGNVLT 397
+++ D+K EN+M +IKI DFGL K + + F G +APE+ N
Sbjct: 267 IVYRDLKLENLMLDKDG--HIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDYG 324
Query: 398 TAYDMWSVGILMGIGLLGYTP 418
A D W +G++M + G P
Sbjct: 325 RAVDWWGLGVVMYEMMCGRLP 345
>AL662889-2|CAH73072.1| 465|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 465
Score = 93.1 bits (221), Expect = 3e-18
Identities = 64/201 (31%), Positives = 101/201 (50%), Gaps = 9/201 (4%)
Query: 225 DFLPLKLIGSGVYGKVMLIRSNAGKQFVAKTVISQYQTNSMEEYS-TL---RILRNT--P 278
DF LKL+G G +GKV+L+R A ++ A ++ + + +E + TL R+L+NT P
Sbjct: 147 DFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHP 206
Query: 279 NIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNG 338
+ L + FVME + GG LF + SE + Y ++ S L Y+H+
Sbjct: 207 FLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSGK 266
Query: 339 LIHFDIKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNF-GFFSSVAPELYSGNVLT 397
+++ D+K EN+M +IKI DFGL K + + F G +APE+ N
Sbjct: 267 IVYRDLKLENLMLDKDG--HIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDYG 324
Query: 398 TAYDMWSVGILMGIGLLGYTP 418
A D W +G++M + G P
Sbjct: 325 RAVDWWGLGVVMYEMMCGRLP 345
>AL592151-2|CAH72892.1| 479|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 479
Score = 93.1 bits (221), Expect = 3e-18
Identities = 64/201 (31%), Positives = 101/201 (50%), Gaps = 9/201 (4%)
Query: 225 DFLPLKLIGSGVYGKVMLIRSNAGKQFVAKTVISQYQTNSMEEYS-TL---RILRNT--P 278
DF LKL+G G +GKV+L+R A ++ A ++ + + +E + TL R+L+NT P
Sbjct: 147 DFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHP 206
Query: 279 NIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNG 338
+ L + FVME + GG LF + SE + Y ++ S L Y+H+
Sbjct: 207 FLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSGK 266
Query: 339 LIHFDIKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNF-GFFSSVAPELYSGNVLT 397
+++ D+K EN+M +IKI DFGL K + + F G +APE+ N
Sbjct: 267 IVYRDLKLENLMLDKDG--HIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDYG 324
Query: 398 TAYDMWSVGILMGIGLLGYTP 418
A D W +G++M + G P
Sbjct: 325 RAVDWWGLGVVMYEMMCGRLP 345
>AL592151-1|CAH72891.1| 465|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 465
Score = 93.1 bits (221), Expect = 3e-18
Identities = 64/201 (31%), Positives = 101/201 (50%), Gaps = 9/201 (4%)
Query: 225 DFLPLKLIGSGVYGKVMLIRSNAGKQFVAKTVISQYQTNSMEEYS-TL---RILRNT--P 278
DF LKL+G G +GKV+L+R A ++ A ++ + + +E + TL R+L+NT P
Sbjct: 147 DFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHP 206
Query: 279 NIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNG 338
+ L + FVME + GG LF + SE + Y ++ S L Y+H+
Sbjct: 207 FLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSGK 266
Query: 339 LIHFDIKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNF-GFFSSVAPELYSGNVLT 397
+++ D+K EN+M +IKI DFGL K + + F G +APE+ N
Sbjct: 267 IVYRDLKLENLMLDKDG--HIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDYG 324
Query: 398 TAYDMWSVGILMGIGLLGYTP 418
A D W +G++M + G P
Sbjct: 325 RAVDWWGLGVVMYEMMCGRLP 345
>AL591721-2|CAH71867.1| 479|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 479
Score = 93.1 bits (221), Expect = 3e-18
Identities = 64/201 (31%), Positives = 101/201 (50%), Gaps = 9/201 (4%)
Query: 225 DFLPLKLIGSGVYGKVMLIRSNAGKQFVAKTVISQYQTNSMEEYS-TL---RILRNT--P 278
DF LKL+G G +GKV+L+R A ++ A ++ + + +E + TL R+L+NT P
Sbjct: 147 DFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHP 206
Query: 279 NIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNG 338
+ L + FVME + GG LF + SE + Y ++ S L Y+H+
Sbjct: 207 FLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSGK 266
Query: 339 LIHFDIKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNF-GFFSSVAPELYSGNVLT 397
+++ D+K EN+M +IKI DFGL K + + F G +APE+ N
Sbjct: 267 IVYRDLKLENLMLDKDG--HIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDYG 324
Query: 398 TAYDMWSVGILMGIGLLGYTP 418
A D W +G++M + G P
Sbjct: 325 RAVDWWGLGVVMYEMMCGRLP 345
>AL591721-1|CAH71866.1| 465|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 465
Score = 93.1 bits (221), Expect = 3e-18
Identities = 64/201 (31%), Positives = 101/201 (50%), Gaps = 9/201 (4%)
Query: 225 DFLPLKLIGSGVYGKVMLIRSNAGKQFVAKTVISQYQTNSMEEYS-TL---RILRNT--P 278
DF LKL+G G +GKV+L+R A ++ A ++ + + +E + TL R+L+NT P
Sbjct: 147 DFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHP 206
Query: 279 NIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNG 338
+ L + FVME + GG LF + SE + Y ++ S L Y+H+
Sbjct: 207 FLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSGK 266
Query: 339 LIHFDIKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNF-GFFSSVAPELYSGNVLT 397
+++ D+K EN+M +IKI DFGL K + + F G +APE+ N
Sbjct: 267 IVYRDLKLENLMLDKDG--HIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDYG 324
Query: 398 TAYDMWSVGILMGIGLLGYTP 418
A D W +G++M + G P
Sbjct: 325 RAVDWWGLGVVMYEMMCGRLP 345
>AL023754-2|CAI19990.1| 245|Homo sapiens
calcium/calmodulin-dependent protein kinase IG protein.
Length = 245
Score = 93.1 bits (221), Expect = 3e-18
Identities = 51/157 (32%), Positives = 91/157 (57%), Gaps = 6/157 (3%)
Query: 217 KSLQNFYRDFLPLKLIGSGVYGKVMLIRSN-AGKQFVAKTVISQ--YQTNSME-EYSTLR 272
K N + F+ ++++GSG + +V L++ GK F K + ++ +S+E E + L+
Sbjct: 14 KQTTNIRKTFIFMEVLGSGAFSEVFLVKQRLTGKLFALKCIKKSPAFRDSSLENEIAVLK 73
Query: 273 ILRNTPNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQ 332
+++ NIV L + Y ++ VM+ + GG LFDR +E+D + ++QV S ++
Sbjct: 74 KIKHE-NIVTLEDIYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVK 132
Query: 333 YIHNNGLIHFDIKPENVMCCS-LNCLNIKIIDFGLTK 368
Y+H NG++H D+KPEN++ + I I DFGL+K
Sbjct: 133 YLHENGIVHRDLKPENLLYLTPEENSKIMITDFGLSK 169
>AJ245709-1|CAB53537.1| 479|Homo sapiens Akt-3 protein protein.
Length = 479
Score = 93.1 bits (221), Expect = 3e-18
Identities = 64/201 (31%), Positives = 101/201 (50%), Gaps = 9/201 (4%)
Query: 225 DFLPLKLIGSGVYGKVMLIRSNAGKQFVAKTVISQYQTNSMEEYS-TL---RILRNT--P 278
DF LKL+G G +GKV+L+R A ++ A ++ + + +E + TL R+L+NT P
Sbjct: 147 DFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHP 206
Query: 279 NIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNG 338
+ L + FVME + GG LF + SE + Y ++ S L Y+H+
Sbjct: 207 FLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSGK 266
Query: 339 LIHFDIKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNF-GFFSSVAPELYSGNVLT 397
+++ D+K EN+M +IKI DFGL K + + F G +APE+ N
Sbjct: 267 IVYRDLKLENLMLDKDG--HIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDYG 324
Query: 398 TAYDMWSVGILMGIGLLGYTP 418
A D W +G++M + G P
Sbjct: 325 RAVDWWGLGVVMYEMMCGRLP 345
>AJ010119-1|CAA09009.1| 772|Homo sapiens Ribosomal protein kinase B
(RSK-B) protein.
Length = 772
Score = 93.1 bits (221), Expect = 3e-18
Identities = 54/192 (28%), Positives = 95/192 (49%), Gaps = 5/192 (2%)
Query: 232 IGSGVYGKVMLIRSN-AGKQFVAKTVISQYQTNSMEEYSTLRILRNTPNIVKLIECYSDG 290
+G G + R +G++F K + + + N+ E + LR+ ++ PN+V L E + D
Sbjct: 417 LGQGSFSVCRRCRQRQSGQEFAVKILSRRLEANTQREVAALRLCQSHPNVVNLHEVHHDQ 476
Query: 291 LNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNN-GLIHFDIKPENV 349
L+ V+E L GG L + + + SE + LR + S + ++H G++H D+KPEN+
Sbjct: 477 LHTYLVLELLRGGELLEHIRKKRHFSESEASQILRSLVSAVSFMHEEAGVVHRDLKPENI 536
Query: 350 MCC-SLNCLNIKIIDFGLTKCARSR--TPINRNFGFFSSVAPELYSGNVLTTAYDMWSVG 406
+ +KIIDFG + P+ APEL + + D+WS+G
Sbjct: 537 LYADDTPGAPVKIIDFGFARLRPQSPGVPMQTPCFTLQYAAPELLAQQGYDESCDLWSLG 596
Query: 407 ILMGIGLLGYTP 418
+++ + L G P
Sbjct: 597 VILYMMLSGQVP 608
Score = 88.2 bits (209), Expect = 9e-17
Identities = 70/241 (29%), Positives = 121/241 (50%), Gaps = 23/241 (9%)
Query: 206 TEPLITSPQYLKSLQNFYRDFLPLKLIGSGVYGKVMLIRS----NAGKQFVAKTVI---- 257
TE +T + S++NF LK++G+G YGKV L+R +AGK + K +
Sbjct: 17 TEANLTGHEEKVSVENFEL----LKVLGTGAYGKVFLVRKAGGHDAGKLYAMKVLRKAAL 72
Query: 258 ---SQYQTNSMEEYSTLRILRNTPNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQC 314
++ Q ++ E S L ++R P +V L + +++ + GG +F Q
Sbjct: 73 VQRAKTQEHTRTERSVLELVRQAPFLVTLHYAFQTDAKLHLILDYVSGGEMFTHLYQRQY 132
Query: 315 ISERDIKIYLRQVCSGLQYIHNNGLIHFDIKPENVMCCSLNCLNIKIIDFGLTKCARSRT 374
E ++++Y ++ L+++H G+I+ D+K ENV+ S +I + DFGL+K +
Sbjct: 133 FKEAEVRVYGGEIVLALEHLHKLGIIYRDLKLENVLLDSEG--HIVLTDFGLSKEFLTEE 190
Query: 375 PINRNFGFFSSV---APELY-SGNVLTTAYDMWSVGILMGIGLLGYTP-RIIGKRSRRLS 429
R F F ++ APE+ S A D WS+GIL+ L G +P + G+R+ +
Sbjct: 191 K-ERTFSFCGTIEYMAPEIIRSKTGHGKAVDWWSLGILLFELLTGASPFTLEGERNTQAE 249
Query: 430 V 430
V
Sbjct: 250 V 250
>AF135794-1|AAD24196.1| 479|Homo sapiens AKT3 protein kinase
protein.
Length = 479
Score = 93.1 bits (221), Expect = 3e-18
Identities = 64/201 (31%), Positives = 101/201 (50%), Gaps = 9/201 (4%)
Query: 225 DFLPLKLIGSGVYGKVMLIRSNAGKQFVAKTVISQYQTNSMEEYS-TL---RILRNT--P 278
DF LKL+G G +GKV+L+R A ++ A ++ + + +E + TL R+L+NT P
Sbjct: 147 DFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHP 206
Query: 279 NIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNG 338
+ L + FVME + GG LF + SE + Y ++ S L Y+H+
Sbjct: 207 FLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSGK 266
Query: 339 LIHFDIKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNF-GFFSSVAPELYSGNVLT 397
+++ D+K EN+M +IKI DFGL K + + F G +APE+ N
Sbjct: 267 IVYRDLKLENLMLDKDG--HIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDYG 324
Query: 398 TAYDMWSVGILMGIGLLGYTP 418
A D W +G++M + G P
Sbjct: 325 RAVDWWGLGVVMYEMMCGRLP 345
>AF124141-1|AAD29089.1| 479|Homo sapiens protein kinase B gamma
protein.
Length = 479
Score = 93.1 bits (221), Expect = 3e-18
Identities = 64/201 (31%), Positives = 101/201 (50%), Gaps = 9/201 (4%)
Query: 225 DFLPLKLIGSGVYGKVMLIRSNAGKQFVAKTVISQYQTNSMEEYS-TL---RILRNT--P 278
DF LKL+G G +GKV+L+R A ++ A ++ + + +E + TL R+L+NT P
Sbjct: 147 DFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHP 206
Query: 279 NIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNG 338
+ L + FVME + GG LF + SE + Y ++ S L Y+H+
Sbjct: 207 FLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSGK 266
Query: 339 LIHFDIKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNF-GFFSSVAPELYSGNVLT 397
+++ D+K EN+M +IKI DFGL K + + F G +APE+ N
Sbjct: 267 IVYRDLKLENLMLDKDG--HIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDYG 324
Query: 398 TAYDMWSVGILMGIGLLGYTP 418
A D W +G++M + G P
Sbjct: 325 RAVDWWGLGVVMYEMMCGRLP 345
>AF085234-1|AAL40392.1| 479|Homo sapiens STK-2 protein.
Length = 479
Score = 93.1 bits (221), Expect = 3e-18
Identities = 64/201 (31%), Positives = 101/201 (50%), Gaps = 9/201 (4%)
Query: 225 DFLPLKLIGSGVYGKVMLIRSNAGKQFVAKTVISQYQTNSMEEYS-TL---RILRNT--P 278
DF LKL+G G +GKV+L+R A ++ A ++ + + +E + TL R+L+NT P
Sbjct: 147 DFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHP 206
Query: 279 NIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNG 338
+ L + FVME + GG LF + SE + Y ++ S L Y+H+
Sbjct: 207 FLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSGK 266
Query: 339 LIHFDIKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNF-GFFSSVAPELYSGNVLT 397
+++ D+K EN+M +IKI DFGL K + + F G +APE+ N
Sbjct: 267 IVYRDLKLENLMLDKDG--HIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDYG 324
Query: 398 TAYDMWSVGILMGIGLLGYTP 418
A D W +G++M + G P
Sbjct: 325 RAVDWWGLGVVMYEMMCGRLP 345
>AF074715-1|AAC67395.1| 705|Homo sapiens mitogen- and
stress-activated protein kinase-2 protein.
Length = 705
Score = 93.1 bits (221), Expect = 3e-18
Identities = 54/192 (28%), Positives = 95/192 (49%), Gaps = 5/192 (2%)
Query: 232 IGSGVYGKVMLIRSN-AGKQFVAKTVISQYQTNSMEEYSTLRILRNTPNIVKLIECYSDG 290
+G G + R +G++F K + + + N+ E + LR+ ++ PN+V L E + D
Sbjct: 395 LGQGSFSVCRRCRQRQSGQEFAVKILSRRLEANTQREVAALRLCQSHPNVVNLHEVHHDQ 454
Query: 291 LNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNN-GLIHFDIKPENV 349
L+ V+E L GG L + + + SE + LR + S + ++H G++H D+KPEN+
Sbjct: 455 LHTYLVLELLRGGELLEHIRKKRHFSESEASQILRSLVSAVSFMHEEAGVVHRDLKPENI 514
Query: 350 MCC-SLNCLNIKIIDFGLTKCARSR--TPINRNFGFFSSVAPELYSGNVLTTAYDMWSVG 406
+ +KIIDFG + P+ APEL + + D+WS+G
Sbjct: 515 LYADDTPGAPVKIIDFGFARLRPQSPGVPMQTPCFTLQYAAPELLAQQGYDESCDLWSLG 574
Query: 407 ILMGIGLLGYTP 418
+++ + L G P
Sbjct: 575 VILYMMLSGQVP 586
Score = 88.2 bits (209), Expect = 9e-17
Identities = 70/241 (29%), Positives = 121/241 (50%), Gaps = 23/241 (9%)
Query: 206 TEPLITSPQYLKSLQNFYRDFLPLKLIGSGVYGKVMLIRS----NAGKQFVAKTVI---- 257
TE +T + S++NF LK++G+G YGKV L+R +AGK + K +
Sbjct: 1 TEANLTGHEEKVSVENFEL----LKVLGTGAYGKVFLVRKAGGHDAGKLYAMKVLRKAAL 56
Query: 258 ---SQYQTNSMEEYSTLRILRNTPNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQC 314
++ Q ++ E S L ++R P +V L + +++ + GG +F Q
Sbjct: 57 VQRAKTQEHTRTERSVLELVRQAPFLVTLHYAFQTDAKLHLILDYVSGGEMFTHLYQRQY 116
Query: 315 ISERDIKIYLRQVCSGLQYIHNNGLIHFDIKPENVMCCSLNCLNIKIIDFGLTKCARSRT 374
E ++++Y ++ L+++H G+I+ D+K ENV+ S +I + DFGL+K +
Sbjct: 117 FKEAEVRVYGGEIVLALEHLHKLGIIYRDLKLENVLLDSEG--HIVLTDFGLSKEFLTEE 174
Query: 375 PINRNFGFFSSV---APELY-SGNVLTTAYDMWSVGILMGIGLLGYTP-RIIGKRSRRLS 429
R F F ++ APE+ S A D WS+GIL+ L G +P + G+R+ +
Sbjct: 175 K-ERTFSFCGTIEYMAPEIIRSKTGHGKAVDWWSLGILLFELLTGASPFTLEGERNTQAE 233
Query: 430 V 430
V
Sbjct: 234 V 234
>L07599-1|AAC82495.1| 580|Homo sapiens ribosomal protein S6 kinase
3 protein.
Length = 580
Score = 92.7 bits (220), Expect = 4e-18
Identities = 69/245 (28%), Positives = 117/245 (47%), Gaps = 13/245 (5%)
Query: 229 LKLIGSGVYGKVMLIRSNAG---KQFVAKTVISQYQTNSMEEYST-----LRILRNTPNI 280
LK++G G +GKV L++ +G +Q A V+ + + T + + N P I
Sbjct: 70 LKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKMERDILVEVNHPFI 129
Query: 281 VKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLI 340
VKL + +++ L GG+LF R +E D+K YL ++ L ++H+ G+I
Sbjct: 130 VKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLGII 189
Query: 341 HFDIKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNF-GFFSSVAPELYSGNVLTTA 399
+ D+KPEN++ +IK+ DFGL+K + +F G +APE+ + T +
Sbjct: 190 YRDLKPENILLDEEG--HIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVVNRRGHTQS 247
Query: 400 YDMWSVGILMGIGLLGYTPRIIGKRSRRLSVVFTSQEYL--CISGAALHFFGKCLHTNPS 457
D WS G+LM L G P R ++++ ++ + +S A NP+
Sbjct: 248 ADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEAQSLLRMLFKRNPA 307
Query: 458 RRLTA 462
RL A
Sbjct: 308 NRLGA 312
Score = 72.1 bits (169), Expect = 6e-12
Identities = 44/143 (30%), Positives = 69/143 (48%), Gaps = 3/143 (2%)
Query: 232 IGSGVYGKVMLIRSNAGKQFVAKTVISQYQTNSMEEYSTLRILRNTPNIVKLIECYSDGL 291
IG G Y A A +I + + + EE L PNI+ L + Y DG
Sbjct: 427 IGVGSYSVCKRCIHKATNMEFAVKIIDKSKRDPTEEIEILLRYGQHPNIITLNDVYDDG- 485
Query: 292 NWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFDIKPENVMC 351
+V+V+ + GG L D+ + SER+ L + ++Y+H G++H D+KP N++
Sbjct: 486 KYVYVVTLMKGGELLDKILRQKFFSEREASAVLFTITKTVEYLHAQGVVHRDLKPSNILY 545
Query: 352 C--SLNCLNIKIIDFGLTKCARS 372
S N +I+I DFG K R+
Sbjct: 546 VDESGNPESIRICDFGFAKQLRA 568
>BC071567-1|AAH71567.1| 765|Homo sapiens SNRK protein protein.
Length = 765
Score = 92.7 bits (220), Expect = 4e-18
Identities = 67/259 (25%), Positives = 122/259 (47%), Gaps = 12/259 (4%)
Query: 230 KLIGSGVYGKVMLIRSNAGKQFVAKTVISQYQTNSM------EEYSTLRILRNTPNIVKL 283
K +G G + V L R + VA VI + + +++ +E ++++++ PNIV+L
Sbjct: 20 KTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKLDTLATGHLFQEVRCMKLVQH-PNIVRL 78
Query: 284 IECYSDGLNWVFVMENLWGGNLFDRF-KHHQCISERDIKIYLRQVCSGLQYIHNNGLIHF 342
E ++E GG++FD KH + ++E K Y Q+ + Y H ++H
Sbjct: 79 YEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAISYCHKLHVVHR 138
Query: 343 DIKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVL-TTAYD 401
D+KPENV+ L +K+ DFG + + + + G + APE+ G+ A D
Sbjct: 139 DLKPENVVFFEKQGL-VKLTDFGFSNKFQPGKKLTTSCGSLAYSAPEILLGDEYDAPAVD 197
Query: 402 MWSVGILMGIGLLGYTPRIIGKRSRRLSVVFTSQEYL--CISGAALHFFGKCLHTNPSRR 459
+WS+G+++ + + G P S L+++ + + +S + L +P RR
Sbjct: 198 IWSLGVILFMLVCGQPPFQEANDSETLTMIMDCKYTVPSHVSKECKDLITRMLQRDPKRR 257
Query: 460 LTAAQALNHPWMFDTCPHP 478
+ NHPW+ P P
Sbjct: 258 AYLEEIENHPWLQGVDPSP 276
>BC021269-1|AAH21269.2| 453|Homo sapiens CAMK2G protein protein.
Length = 453
Score = 92.7 bits (220), Expect = 4e-18
Identities = 60/209 (28%), Positives = 107/209 (51%), Gaps = 11/209 (5%)
Query: 272 RILRNTPNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGL 331
R+L++ PNIV+L + S+ V + + GG LF+ + SE D + Q+ +
Sbjct: 1 RLLKH-PNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESV 59
Query: 332 QYIHNNGLIHFDIKPENVMCCSLNCLN--IKIIDFGLTKCARSRTPINRNF-GFFSSVAP 388
+IH + ++H D+KPEN++ S C +K+ DFGL + F G ++P
Sbjct: 60 NHIHQHDIVHRDLKPENLLLAS-KCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSP 118
Query: 389 ELYSGNVLTTAYDMWSVGILMGIGLLGYTP------RIIGKRSRRLSVVFTSQEYLCISG 442
E+ + D+W+ G+++ I L+GY P + ++ + + F S E+ ++
Sbjct: 119 EVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTP 178
Query: 443 AALHFFGKCLHTNPSRRLTAAQALNHPWM 471
A + + L NP++R+TA QAL HPW+
Sbjct: 179 EAKNLINQMLTINPAKRITADQALKHPWV 207
>AL713896-1|CAI13787.1| 453|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II gamma protein.
Length = 453
Score = 92.7 bits (220), Expect = 4e-18
Identities = 60/209 (28%), Positives = 107/209 (51%), Gaps = 11/209 (5%)
Query: 272 RILRNTPNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGL 331
R+L++ PNIV+L + S+ V + + GG LF+ + SE D + Q+ +
Sbjct: 1 RLLKH-PNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESV 59
Query: 332 QYIHNNGLIHFDIKPENVMCCSLNCLN--IKIIDFGLTKCARSRTPINRNF-GFFSSVAP 388
+IH + ++H D+KPEN++ S C +K+ DFGL + F G ++P
Sbjct: 60 NHIHQHDIVHRDLKPENLLLAS-KCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSP 118
Query: 389 ELYSGNVLTTAYDMWSVGILMGIGLLGYTP------RIIGKRSRRLSVVFTSQEYLCISG 442
E+ + D+W+ G+++ I L+GY P + ++ + + F S E+ ++
Sbjct: 119 EVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTP 178
Query: 443 AALHFFGKCLHTNPSRRLTAAQALNHPWM 471
A + + L NP++R+TA QAL HPW+
Sbjct: 179 EAKNLINQMLTINPAKRITADQALKHPWV 207
>AL596247-1|CAI13964.1| 453|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II gamma protein.
Length = 453
Score = 92.7 bits (220), Expect = 4e-18
Identities = 60/209 (28%), Positives = 107/209 (51%), Gaps = 11/209 (5%)
Query: 272 RILRNTPNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGL 331
R+L++ PNIV+L + S+ V + + GG LF+ + SE D + Q+ +
Sbjct: 1 RLLKH-PNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESV 59
Query: 332 QYIHNNGLIHFDIKPENVMCCSLNCLN--IKIIDFGLTKCARSRTPINRNF-GFFSSVAP 388
+IH + ++H D+KPEN++ S C +K+ DFGL + F G ++P
Sbjct: 60 NHIHQHDIVHRDLKPENLLLAS-KCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSP 118
Query: 389 ELYSGNVLTTAYDMWSVGILMGIGLLGYTP------RIIGKRSRRLSVVFTSQEYLCISG 442
E+ + D+W+ G+++ I L+GY P + ++ + + F S E+ ++
Sbjct: 119 EVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTP 178
Query: 443 AALHFFGKCLHTNPSRRLTAAQALNHPWM 471
A + + L NP++R+TA QAL HPW+
Sbjct: 179 EAKNLINQMLTINPAKRITADQALKHPWV 207
>M34181-1|AAA60170.1| 351|Homo sapiens cAMP-dependent protein
kinase catalytic subunit protein.
Length = 351
Score = 92.3 bits (219), Expect = 5e-18
Identities = 61/200 (30%), Positives = 101/200 (50%), Gaps = 10/200 (5%)
Query: 225 DFLPLKLIGSGVYGKVMLIRSNAGKQFVAKTVISQYQTNSMEEYS-TL---RILR--NTP 278
DF K +G+G +G+VML++ A +Q+ A ++ + + +++ TL RIL+ N P
Sbjct: 43 DFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFP 102
Query: 279 NIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNG 338
+V+L + D N VME + GG +F + SE + Y Q+ +Y+H+
Sbjct: 103 FLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLD 162
Query: 339 LIHFDIKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLTT 398
LI+ D+KPEN++ I++ DFG K + RT G +APE+
Sbjct: 163 LIYRDLKPENLLIDHQG--YIQVTDFGFAKRVKGRT--WTLCGTPEYLAPEIILSKGYNK 218
Query: 399 AYDMWSVGILMGIGLLGYTP 418
A D W++G+L+ GY P
Sbjct: 219 AVDWWALGVLIYEMAAGYPP 238
>DQ667174-1|ABG25919.1| 398|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 398
Score = 92.3 bits (219), Expect = 5e-18
Identities = 61/200 (30%), Positives = 101/200 (50%), Gaps = 10/200 (5%)
Query: 225 DFLPLKLIGSGVYGKVMLIRSNAGKQFVAKTVISQYQTNSMEEYS-TL---RILR--NTP 278
DF K +G+G +G+VML++ A +Q+ A ++ + + +++ TL RIL+ N P
Sbjct: 90 DFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFP 149
Query: 279 NIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNG 338
+V+L + D N VME + GG +F + SE + Y Q+ +Y+H+
Sbjct: 150 FLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLD 209
Query: 339 LIHFDIKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLTT 398
LI+ D+KPEN++ I++ DFG K + RT G +APE+
Sbjct: 210 LIYRDLKPENLLIDHQG--YIQVTDFGFAKRVKGRT--WTLCGTPEYLAPEIILSKGYNK 265
Query: 399 AYDMWSVGILMGIGLLGYTP 418
A D W++G+L+ GY P
Sbjct: 266 AVDWWALGVLIYEMAAGYPP 285
>BC121154-1|AAI21155.1| 465|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 465
Score = 92.3 bits (219), Expect = 5e-18
Identities = 64/201 (31%), Positives = 101/201 (50%), Gaps = 9/201 (4%)
Query: 225 DFLPLKLIGSGVYGKVMLIRSNAGKQFVAKTVISQYQTNSMEEYS-TL---RILRNT--P 278
DF LKL+G G +GKV+L+R A ++ A ++ + + +E + TL R+L+NT P
Sbjct: 147 DFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHP 206
Query: 279 NIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNG 338
+ L + FVME + GG LF + SE + Y ++ S L Y+H+
Sbjct: 207 FLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSGK 266
Query: 339 LIHFDIKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNF-GFFSSVAPELYSGNVLT 397
+++ D+K EN+M +IKI DFGL K + + F G +APE+ N
Sbjct: 267 IVYRDLKLENLMRDKDG--HIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDYG 324
Query: 398 TAYDMWSVGILMGIGLLGYTP 418
A D W +G++M + G P
Sbjct: 325 RAVDWWGLGVVMYEMMCGRLP 345
>BC016285-1|AAH16285.1| 257|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 257
Score = 92.3 bits (219), Expect = 5e-18
Identities = 61/200 (30%), Positives = 101/200 (50%), Gaps = 10/200 (5%)
Query: 225 DFLPLKLIGSGVYGKVMLIRSNAGKQFVAKTVISQYQTNSMEEYS-TL---RILR--NTP 278
DF K +G+G +G+VML++ A +Q+ A ++ + + +++ TL RIL+ N P
Sbjct: 43 DFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFP 102
Query: 279 NIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNG 338
+V+L + D N VME + GG +F + SE + Y Q+ +Y+H+
Sbjct: 103 FLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLD 162
Query: 339 LIHFDIKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLTT 398
LI+ D+KPEN++ I++ DFG K + RT G +APE+
Sbjct: 163 LIYRDLKPENLLIDHQG--YIQVTDFGFAKRVKGRT--WTLCGTPEYLAPEIILSKGYNK 218
Query: 399 AYDMWSVGILMGIGLLGYTP 418
A D W++G+L+ GY P
Sbjct: 219 AVDWWALGVLIYEMAAGYPP 238
>AY120867-1|AAM55491.1| 752|Homo sapiens MAP/microtubule
affinity-regulating kinase-like 1 protein.
Length = 752
Score = 92.3 bits (219), Expect = 5e-18
Identities = 72/252 (28%), Positives = 116/252 (46%), Gaps = 12/252 (4%)
Query: 229 LKLIGSGVYGKVMLIRSNAGKQFVAKTVISQYQTN--SMEE-YSTLRILR--NTPNIVKL 283
L+ IG G + KV L R + VA +I + Q N S+++ + +RI++ N PNIVKL
Sbjct: 62 LRTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPSSLQKLFREVRIMKGLNHPNIVKL 121
Query: 284 IECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFD 343
E VME G +FD H + E++ + RQ+ S + Y H ++H D
Sbjct: 122 FEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIVHRD 181
Query: 344 IKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLT-TAYDM 402
+K EN++ + NIKI DFG + + ++ G APEL+ G D+
Sbjct: 182 LKAENLLLDAE--ANIKIADFGFSNEFTLGSKLDTFCGSPPYAAPELFQGKKYDGPEVDI 239
Query: 403 WSVGILMGIGLLGYTPRIIGKRSRRLSVVFTSQEY---LCISGAALHFFGKCLHTNPSRR 459
WS+G+++ + G P G + L +Y +S + L NP++R
Sbjct: 240 WSLGVILYTLVSGSLP-FDGHNLKELRERVLRGKYRVPFYMSTDCESILRRFLVLNPAKR 298
Query: 460 LTAAQALNHPWM 471
T Q + W+
Sbjct: 299 CTLEQIMKDKWI 310
>AY057448-1|AAL23683.1| 752|Homo sapiens MARK4 serine/threonine
protein kinase protein.
Length = 752
Score = 92.3 bits (219), Expect = 5e-18
Identities = 72/252 (28%), Positives = 116/252 (46%), Gaps = 12/252 (4%)
Query: 229 LKLIGSGVYGKVMLIRSNAGKQFVAKTVISQYQTN--SMEE-YSTLRILR--NTPNIVKL 283
L+ IG G + KV L R + VA +I + Q N S+++ + +RI++ N PNIVKL
Sbjct: 62 LRTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPSSLQKLFREVRIMKGLNHPNIVKL 121
Query: 284 IECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFD 343
E VME G +FD H + E++ + RQ+ S + Y H ++H D
Sbjct: 122 FEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIVHRD 181
Query: 344 IKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLT-TAYDM 402
+K EN++ + NIKI DFG + + ++ G APEL+ G D+
Sbjct: 182 LKAENLLLDAE--ANIKIADFGFSNEFTLGSKLDTFCGSPPYAAPELFQGKKYDGPEVDI 239
Query: 403 WSVGILMGIGLLGYTPRIIGKRSRRLSVVFTSQEY---LCISGAALHFFGKCLHTNPSRR 459
WS+G+++ + G P G + L +Y +S + L NP++R
Sbjct: 240 WSLGVILYTLVSGSLP-FDGHNLKELRERVLRGKYRVPFYMSTDCESILRRFLVLNPAKR 298
Query: 460 LTAAQALNHPWM 471
T Q + W+
Sbjct: 299 CTLEQIMKDKWI 310
>AL450063-11|CAI16854.1| 264|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 264
Score = 92.3 bits (219), Expect = 5e-18
Identities = 61/200 (30%), Positives = 101/200 (50%), Gaps = 10/200 (5%)
Query: 225 DFLPLKLIGSGVYGKVMLIRSNAGKQFVAKTVISQYQTNSMEEYS-TL---RILR--NTP 278
DF K +G+G +G+VML++ A +Q+ A ++ + + +++ TL RIL+ N P
Sbjct: 49 DFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFP 108
Query: 279 NIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNG 338
+V+L + D N VME + GG +F + SE + Y Q+ +Y+H+
Sbjct: 109 FLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLD 168
Query: 339 LIHFDIKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLTT 398
LI+ D+KPEN++ I++ DFG K + RT G +APE+
Sbjct: 169 LIYRDLKPENLLIDHQG--YIQVTDFGFAKRVKGRT--WTLCGTPEYLAPEIILSKGYNK 224
Query: 399 AYDMWSVGILMGIGLLGYTP 418
A D W++G+L+ GY P
Sbjct: 225 AVDWWALGVLIYEMAAGYPP 244
>AL450063-7|CAI16850.1| 245|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 245
Score = 92.3 bits (219), Expect = 5e-18
Identities = 61/200 (30%), Positives = 101/200 (50%), Gaps = 10/200 (5%)
Query: 225 DFLPLKLIGSGVYGKVMLIRSNAGKQFVAKTVISQYQTNSMEEYS-TL---RILR--NTP 278
DF K +G+G +G+VML++ A +Q+ A ++ + + +++ TL RIL+ N P
Sbjct: 31 DFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFP 90
Query: 279 NIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNG 338
+V+L + D N VME + GG +F + SE + Y Q+ +Y+H+
Sbjct: 91 FLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLD 150
Query: 339 LIHFDIKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLTT 398
LI+ D+KPEN++ I++ DFG K + RT G +APE+
Sbjct: 151 LIYRDLKPENLLIDHQG--YIQVTDFGFAKRVKGRT--WTLCGTPEYLAPEIILSKGYNK 206
Query: 399 AYDMWSVGILMGIGLLGYTP 418
A D W++G+L+ GY P
Sbjct: 207 AVDWWALGVLIYEMAAGYPP 226
>AL450063-3|CAI16846.1| 398|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 398
Score = 92.3 bits (219), Expect = 5e-18
Identities = 61/200 (30%), Positives = 101/200 (50%), Gaps = 10/200 (5%)
Query: 225 DFLPLKLIGSGVYGKVMLIRSNAGKQFVAKTVISQYQTNSMEEYS-TL---RILR--NTP 278
DF K +G+G +G+VML++ A +Q+ A ++ + + +++ TL RIL+ N P
Sbjct: 90 DFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFP 149
Query: 279 NIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNG 338
+V+L + D N VME + GG +F + SE + Y Q+ +Y+H+
Sbjct: 150 FLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLD 209
Query: 339 LIHFDIKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLTT 398
LI+ D+KPEN++ I++ DFG K + RT G +APE+
Sbjct: 210 LIYRDLKPENLLIDHQG--YIQVTDFGFAKRVKGRT--WTLCGTPEYLAPEIILSKGYNK 265
Query: 399 AYDMWSVGILMGIGLLGYTP 418
A D W++G+L+ GY P
Sbjct: 266 AVDWWALGVLIYEMAAGYPP 285
>AL450063-2|CAI16845.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 351
Score = 92.3 bits (219), Expect = 5e-18
Identities = 61/200 (30%), Positives = 101/200 (50%), Gaps = 10/200 (5%)
Query: 225 DFLPLKLIGSGVYGKVMLIRSNAGKQFVAKTVISQYQTNSMEEYS-TL---RILR--NTP 278
DF K +G+G +G+VML++ A +Q+ A ++ + + +++ TL RIL+ N P
Sbjct: 43 DFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFP 102
Query: 279 NIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNG 338
+V+L + D N VME + GG +F + SE + Y Q+ +Y+H+
Sbjct: 103 FLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLD 162
Query: 339 LIHFDIKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLTT 398
LI+ D+KPEN++ I++ DFG K + RT G +APE+
Sbjct: 163 LIYRDLKPENLLIDHQG--YIQVTDFGFAKRVKGRT--WTLCGTPEYLAPEIILSKGYNK 218
Query: 399 AYDMWSVGILMGIGLLGYTP 418
A D W++G+L+ GY P
Sbjct: 219 AVDWWALGVLIYEMAAGYPP 238
>AL450063-1|CAI16844.1| 257|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 257
Score = 92.3 bits (219), Expect = 5e-18
Identities = 61/200 (30%), Positives = 101/200 (50%), Gaps = 10/200 (5%)
Query: 225 DFLPLKLIGSGVYGKVMLIRSNAGKQFVAKTVISQYQTNSMEEYS-TL---RILR--NTP 278
DF K +G+G +G+VML++ A +Q+ A ++ + + +++ TL RIL+ N P
Sbjct: 43 DFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFP 102
Query: 279 NIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNG 338
+V+L + D N VME + GG +F + SE + Y Q+ +Y+H+
Sbjct: 103 FLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLD 162
Query: 339 LIHFDIKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLTT 398
LI+ D+KPEN++ I++ DFG K + RT G +APE+
Sbjct: 163 LIYRDLKPENLLIDHQG--YIQVTDFGFAKRVKGRT--WTLCGTPEYLAPEIILSKGYNK 218
Query: 399 AYDMWSVGILMGIGLLGYTP 418
A D W++G+L+ GY P
Sbjct: 219 AVDWWALGVLIYEMAAGYPP 238
>AL359504-2|CAI14541.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 351
Score = 92.3 bits (219), Expect = 5e-18
Identities = 61/200 (30%), Positives = 101/200 (50%), Gaps = 10/200 (5%)
Query: 225 DFLPLKLIGSGVYGKVMLIRSNAGKQFVAKTVISQYQTNSMEEYS-TL---RILR--NTP 278
DF K +G+G +G+VML++ A +Q+ A ++ + + +++ TL RIL+ N P
Sbjct: 43 DFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFP 102
Query: 279 NIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNG 338
+V+L + D N VME + GG +F + SE + Y Q+ +Y+H+
Sbjct: 103 FLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLD 162
Query: 339 LIHFDIKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLTT 398
LI+ D+KPEN++ I++ DFG K + RT G +APE+
Sbjct: 163 LIYRDLKPENLLIDHQG--YIQVTDFGFAKRVKGRT--WTLCGTPEYLAPEIILSKGYNK 218
Query: 399 AYDMWSVGILMGIGLLGYTP 418
A D W++G+L+ GY P
Sbjct: 219 AVDWWALGVLIYEMAAGYPP 238
>AL359504-1|CAI14540.1| 257|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 257
Score = 92.3 bits (219), Expect = 5e-18
Identities = 61/200 (30%), Positives = 101/200 (50%), Gaps = 10/200 (5%)
Query: 225 DFLPLKLIGSGVYGKVMLIRSNAGKQFVAKTVISQYQTNSMEEYS-TL---RILR--NTP 278
DF K +G+G +G+VML++ A +Q+ A ++ + + +++ TL RIL+ N P
Sbjct: 43 DFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFP 102
Query: 279 NIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNG 338
+V+L + D N VME + GG +F + SE + Y Q+ +Y+H+
Sbjct: 103 FLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLD 162
Query: 339 LIHFDIKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLTT 398
LI+ D+KPEN++ I++ DFG K + RT G +APE+
Sbjct: 163 LIYRDLKPENLLIDHQG--YIQVTDFGFAKRVKGRT--WTLCGTPEYLAPEIILSKGYNK 218
Query: 399 AYDMWSVGILMGIGLLGYTP 418
A D W++G+L+ GY P
Sbjct: 219 AVDWWALGVLIYEMAAGYPP 238
>AK075272-1|BAC11510.1| 752|Homo sapiens protein ( Homo sapiens
cDNA FLJ90791 fis, clone THYRO1001593, moderately
similar to PUTATIVE SERINE/THREONINE-PROTEIN KINASE P78
(EC 2.7.1.-). ).
Length = 752
Score = 92.3 bits (219), Expect = 5e-18
Identities = 72/252 (28%), Positives = 116/252 (46%), Gaps = 12/252 (4%)
Query: 229 LKLIGSGVYGKVMLIRSNAGKQFVAKTVISQYQTN--SMEE-YSTLRILR--NTPNIVKL 283
L+ IG G + KV L R + VA +I + Q N S+++ + +RI++ N PNIVKL
Sbjct: 62 LRTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPSSLQKLFREVRIMKGLNHPNIVKL 121
Query: 284 IECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFD 343
E VME G +FD H + E++ + RQ+ S + Y H ++H D
Sbjct: 122 FEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIVHRD 181
Query: 344 IKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLT-TAYDM 402
+K EN++ + NIKI DFG + + ++ G APEL+ G D+
Sbjct: 182 LKAENLLLDAE--ANIKIADFGFSNEFTLGSKLDTFCGSPPYAAPELFQGKKYDGPEVDI 239
Query: 403 WSVGILMGIGLLGYTPRIIGKRSRRLSVVFTSQEY---LCISGAALHFFGKCLHTNPSRR 459
WS+G+++ + G P G + L +Y +S + L NP++R
Sbjct: 240 WSLGVILYTLVSGSLP-FDGHNLKELRERVLRGKYRVPFYMSTDCESILRRFLVLNPAKR 298
Query: 460 LTAAQALNHPWM 471
T Q + W+
Sbjct: 299 CTLEQIMKDKWI 310
>AB209189-1|BAD92426.1| 365|Homo sapiens cAMP-dependent protein
kinase catalytic subunit beta isoform 2 variant protein.
Length = 365
Score = 92.3 bits (219), Expect = 5e-18
Identities = 61/200 (30%), Positives = 101/200 (50%), Gaps = 10/200 (5%)
Query: 225 DFLPLKLIGSGVYGKVMLIRSNAGKQFVAKTVISQYQTNSMEEYS-TL---RILR--NTP 278
DF K +G+G +G+VML++ A +Q+ A ++ + + +++ TL RIL+ N P
Sbjct: 69 DFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFP 128
Query: 279 NIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNG 338
+V+L + D N VME + GG +F + SE + Y Q+ +Y+H+
Sbjct: 129 FLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLD 188
Query: 339 LIHFDIKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLTT 398
LI+ D+KPEN++ I++ DFG K + RT G +APE+
Sbjct: 189 LIYRDLKPENLLIDHQG--YIQVTDFGFAKRVKGRT--WTLCGTPEYLAPEIILSKGYNK 244
Query: 399 AYDMWSVGILMGIGLLGYTP 418
A D W++G+L+ GY P
Sbjct: 245 AVDWWALGVLIYEMAAGYPP 264
>AB058763-1|BAB47489.1| 689|Homo sapiens KIAA1860 protein protein.
Length = 689
Score = 92.3 bits (219), Expect = 5e-18
Identities = 72/252 (28%), Positives = 116/252 (46%), Gaps = 12/252 (4%)
Query: 229 LKLIGSGVYGKVMLIRSNAGKQFVAKTVISQYQTN--SMEE-YSTLRILR--NTPNIVKL 283
L+ IG G + KV L R + VA +I + Q N S+++ + +RI++ N PNIVKL
Sbjct: 63 LRTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPSSLQKLFREVRIMKGLNHPNIVKL 122
Query: 284 IECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFD 343
E VME G +FD H + E++ + RQ+ S + Y H ++H D
Sbjct: 123 FEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIVHRD 182
Query: 344 IKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLT-TAYDM 402
+K EN++ + NIKI DFG + + ++ G APEL+ G D+
Sbjct: 183 LKAENLLLDAE--ANIKIADFGFSNEFTLGSKLDTFCGSPPYAAPELFQGKKYDGPEVDI 240
Query: 403 WSVGILMGIGLLGYTPRIIGKRSRRLSVVFTSQEY---LCISGAALHFFGKCLHTNPSRR 459
WS+G+++ + G P G + L +Y +S + L NP++R
Sbjct: 241 WSLGVILYTLVSGSLP-FDGHNLKELRERVLRGKYRVPFYMSTDCESILRRFLVLNPAKR 299
Query: 460 LTAAQALNHPWM 471
T Q + W+
Sbjct: 300 CTLEQIMKDKWI 311
>AB011109-1|BAA25463.2| 698|Homo sapiens KIAA0537 protein protein.
Length = 698
Score = 92.3 bits (219), Expect = 5e-18
Identities = 71/249 (28%), Positives = 112/249 (44%), Gaps = 12/249 (4%)
Query: 232 IGSGVYGKVMLIRSNAGKQFVAKTVISQYQTNSMEEYSTLR----ILR--NTPNIVKLIE 285
+G G YGKV + VA I + + ++ +R I+ N P+I+ + E
Sbjct: 98 LGKGTYGKVKRATERFSGRVVAIKSIRKDKIKDEQDMVHIRREIEIMSSLNHPHIISIYE 157
Query: 286 CYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFDIK 345
+ + V +ME G L+D + +SER+ + + RQ+ S + Y H NG++H D+K
Sbjct: 158 VFENKDKIVIIMEYASKGELYDYISERRRLSERETRHFFRQIVSAVHYCHKNGVVHRDLK 217
Query: 346 PENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVAPELYSGNVLT-TAYDMWS 404
EN++ NC NIKI DFGL+ + + G +PE+ +G D W+
Sbjct: 218 LENILLDD-NC-NIKIADFGLSNLYQKDKFLQTFCGSPLYASPEIVNGRPYRGPEVDSWA 275
Query: 405 VGILMGIGLLGYTPRIIGKRSRRLSVVFTSQEYL--CISGAALHFFGKCLHTNPSRRLTA 462
+G+L+ + G P G + L +S EY A L NP RR T
Sbjct: 276 LGVLLYTLVYGTMP-FDGFDHKNLIRQISSGEYREPTQPSDARGLIRWMLMVNPDRRATI 334
Query: 463 AQALNHPWM 471
NH W+
Sbjct: 335 EDIANHWWV 343
>U23460-1|AAC99802.1| 664|Homo sapiens proline rich
calmodulin-dependent protein kinase protein.
Length = 664
Score = 91.5 bits (217), Expect = 9e-18
Identities = 67/256 (26%), Positives = 122/256 (47%), Gaps = 19/256 (7%)
Query: 232 IGSGVYGKVM-LIRSNAGKQFVAKTV----ISQYQTNSMEEYSTLRILRNTPNIVKLIEC 286
IG G + V ++ G ++ AK + +S +E + + L NIV+L +
Sbjct: 20 IGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKHSNIVRLHDS 79
Query: 287 YSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFDIKP 346
S+ V + + GG LF+ + SE D ++Q+ + + H G++H D+KP
Sbjct: 80 ISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKP 139
Query: 347 ENVMCCSLNCLN--IKIIDFGLTKCARSRTPINRNFGFFSS---VAPELYSGNVLTTAYD 401
EN++ S C +K+ DFGL + FGF + ++PE+ D
Sbjct: 140 ENLLLAS-KCKGAAVKLADFGL--AIEVQGDQQAWFGFAGTPGYLSPEVLRKEAYGKPVD 196
Query: 402 MWSVGILMGIGLLGYTP------RIIGKRSRRLSVVFTSQEYLCISGAALHFFGKCLHTN 455
+W+ G+++ I L+GY P + ++ + + F S E+ ++ A + + L N
Sbjct: 197 IWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTIN 256
Query: 456 PSRRLTAAQALNHPWM 471
P++R+TA +AL HPW+
Sbjct: 257 PAKRITAHEALKHPWV 272
>L07043-1|AAB61379.1| 306|Homo sapiens calcium/calmodulin-dependent
protein kinase isoform A protein.
Length = 306
Score = 91.5 bits (217), Expect = 9e-18
Identities = 58/203 (28%), Positives = 102/203 (50%), Gaps = 10/203 (4%)
Query: 278 PNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNN 337
PNIV+L + S+ V + + GG LF+ + SE D + Q+ + +IH +
Sbjct: 4 PNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQH 63
Query: 338 GLIHFDIKPENVMCCSLNCLN--IKIIDFGLTKCARSRTPINRNF-GFFSSVAPELYSGN 394
++H D+KPEN++ S C +K+ DFGL + F G ++PE+ +
Sbjct: 64 DIVHRDLKPENLLLAS-KCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGYLSPEVLRKD 122
Query: 395 VLTTAYDMWSVGILMGIGLLGYTP------RIIGKRSRRLSVVFTSQEYLCISGAALHFF 448
D+W+ G+++ I L+GY P + ++ + + F S E+ ++ A +
Sbjct: 123 PYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGTYDFPSPEWDTVTPEAKNLI 182
Query: 449 GKCLHTNPSRRLTAAQALNHPWM 471
+ L NP++R+TA QAL HPW+
Sbjct: 183 NQMLTINPAKRITADQALKHPWV 205
>BC019070-1|AAH19070.1| 503|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II beta protein.
Length = 503
Score = 91.5 bits (217), Expect = 9e-18
Identities = 67/256 (26%), Positives = 122/256 (47%), Gaps = 19/256 (7%)
Query: 232 IGSGVYGKVM-LIRSNAGKQFVAKTV----ISQYQTNSMEEYSTLRILRNTPNIVKLIEC 286
IG G + V ++ G ++ AK + +S +E + + L NIV+L +
Sbjct: 20 IGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKHSNIVRLHDS 79
Query: 287 YSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFDIKP 346
S+ V + + GG LF+ + SE D ++Q+ + + H G++H D+KP
Sbjct: 80 ISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKP 139
Query: 347 ENVMCCSLNCLN--IKIIDFGLTKCARSRTPINRNFGFFSS---VAPELYSGNVLTTAYD 401
EN++ S C +K+ DFGL + FGF + ++PE+ D
Sbjct: 140 ENLLLAS-KCKGAAVKLADFGL--AIEVQGDQQAWFGFAGTPGYLSPEVLRKEAYGKPVD 196
Query: 402 MWSVGILMGIGLLGYTP------RIIGKRSRRLSVVFTSQEYLCISGAALHFFGKCLHTN 455
+W+ G+++ I L+GY P + ++ + + F S E+ ++ A + + L N
Sbjct: 197 IWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTIN 256
Query: 456 PSRRLTAAQALNHPWM 471
P++R+TA +AL HPW+
Sbjct: 257 PAKRITAHEALKHPWV 272
>AK222703-1|BAD96423.1| 542|Homo sapiens
calcium/calmodulin-dependent protein kinase IIB isoform
2 variant protein.
Length = 542
Score = 91.5 bits (217), Expect = 9e-18
Identities = 67/256 (26%), Positives = 122/256 (47%), Gaps = 19/256 (7%)
Query: 232 IGSGVYGKVM-LIRSNAGKQFVAKTV----ISQYQTNSMEEYSTLRILRNTPNIVKLIEC 286
IG G + V ++ G ++ AK + +S +E + + L NIV+L +
Sbjct: 20 IGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKHSNIVRLHDS 79
Query: 287 YSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFDIKP 346
S+ V + + GG LF+ + SE D ++Q+ + + H G++H D+KP
Sbjct: 80 ISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKP 139
Query: 347 ENVMCCSLNCLN--IKIIDFGLTKCARSRTPINRNFGFFSS---VAPELYSGNVLTTAYD 401
EN++ S C +K+ DFGL + FGF + ++PE+ D
Sbjct: 140 ENLLLAS-KCKGAAVKLADFGL--AIEVQGDQQAWFGFAGTPGYLSPEVLRKEAYGKPVD 196
Query: 402 MWSVGILMGIGLLGYTP------RIIGKRSRRLSVVFTSQEYLCISGAALHFFGKCLHTN 455
+W+ G+++ I L+GY P + ++ + + F S E+ ++ A + + L N
Sbjct: 197 IWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTIN 256
Query: 456 PSRRLTAAQALNHPWM 471
P++R+TA +AL HPW+
Sbjct: 257 PAKRITAHEALKHPWV 272
>AJ252238-1|CAB65122.1| 518|Homo sapiens calcium/calmodulin
dependent protein kinase II beta 4 protein.
Length = 518
Score = 91.5 bits (217), Expect = 9e-18
Identities = 67/256 (26%), Positives = 122/256 (47%), Gaps = 19/256 (7%)
Query: 232 IGSGVYGKVM-LIRSNAGKQFVAKTV----ISQYQTNSMEEYSTLRILRNTPNIVKLIEC 286
IG G + V ++ G ++ AK + +S +E + + L NIV+L +
Sbjct: 20 IGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKHSNIVRLHDS 79
Query: 287 YSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFDIKP 346
S+ V + + GG LF+ + SE D ++Q+ + + H G++H D+KP
Sbjct: 80 ISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKP 139
Query: 347 ENVMCCSLNCLN--IKIIDFGLTKCARSRTPINRNFGFFSS---VAPELYSGNVLTTAYD 401
EN++ S C +K+ DFGL + FGF + ++PE+ D
Sbjct: 140 ENLLLAS-KCKGAAVKLADFGL--AIEVQGDQQAWFGFAGTPGYLSPEVLRKEAYGKPVD 196
Query: 402 MWSVGILMGIGLLGYTP------RIIGKRSRRLSVVFTSQEYLCISGAALHFFGKCLHTN 455
+W+ G+++ I L+GY P + ++ + + F S E+ ++ A + + L N
Sbjct: 197 IWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTIN 256
Query: 456 PSRRLTAAQALNHPWM 471
P++R+TA +AL HPW+
Sbjct: 257 PAKRITAHEALKHPWV 272
>AJ252237-1|CAB65121.1| 479|Homo sapiens calcium/calmodulin
dependent protein kinase II beta 2 protein.
Length = 479
Score = 91.5 bits (217), Expect = 9e-18
Identities = 67/256 (26%), Positives = 122/256 (47%), Gaps = 19/256 (7%)
Query: 232 IGSGVYGKVM-LIRSNAGKQFVAKTV----ISQYQTNSMEEYSTLRILRNTPNIVKLIEC 286
IG G + V ++ G ++ AK + +S +E + + L NIV+L +
Sbjct: 20 IGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKHSNIVRLHDS 79
Query: 287 YSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFDIKP 346
S+ V + + GG LF+ + SE D ++Q+ + + H G++H D+KP
Sbjct: 80 ISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKP 139
Query: 347 ENVMCCSLNCLN--IKIIDFGLTKCARSRTPINRNFGFFSS---VAPELYSGNVLTTAYD 401
EN++ S C +K+ DFGL + FGF + ++PE+ D
Sbjct: 140 ENLLLAS-KCKGAAVKLADFGL--AIEVQGDQQAWFGFAGTPGYLSPEVLRKEAYGKPVD 196
Query: 402 MWSVGILMGIGLLGYTP------RIIGKRSRRLSVVFTSQEYLCISGAALHFFGKCLHTN 455
+W+ G+++ I L+GY P + ++ + + F S E+ ++ A + + L N
Sbjct: 197 IWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTIN 256
Query: 456 PSRRLTAAQALNHPWM 471
P++R+TA +AL HPW+
Sbjct: 257 PAKRITAHEALKHPWV 272
>AJ252236-1|CAB65120.1| 503|Homo sapiens calcium/calmodulin
dependent protein kinase II beta 1 protein.
Length = 503
Score = 91.5 bits (217), Expect = 9e-18
Identities = 67/256 (26%), Positives = 122/256 (47%), Gaps = 19/256 (7%)
Query: 232 IGSGVYGKVM-LIRSNAGKQFVAKTV----ISQYQTNSMEEYSTLRILRNTPNIVKLIEC 286
IG G + V ++ G ++ AK + +S +E + + L NIV+L +
Sbjct: 20 IGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKHSNIVRLHDS 79
Query: 287 YSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFDIKP 346
S+ V + + GG LF+ + SE D ++Q+ + + H G++H D+KP
Sbjct: 80 ISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKP 139
Query: 347 ENVMCCSLNCLN--IKIIDFGLTKCARSRTPINRNFGFFSS---VAPELYSGNVLTTAYD 401
EN++ S C +K+ DFGL + FGF + ++PE+ D
Sbjct: 140 ENLLLAS-KCKGAAVKLADFGL--AIEVQGDQQAWFGFAGTPGYLSPEVLRKEAYGKPVD 196
Query: 402 MWSVGILMGIGLLGYTP------RIIGKRSRRLSVVFTSQEYLCISGAALHFFGKCLHTN 455
+W+ G+++ I L+GY P + ++ + + F S E+ ++ A + + L N
Sbjct: 197 IWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTIN 256
Query: 456 PSRRLTAAQALNHPWM 471
P++R+TA +AL HPW+
Sbjct: 257 PAKRITAHEALKHPWV 272
>AF140350-1|AAD42070.1| 449|Homo sapiens
calcium/calmodulin-dependent protein kinase II beta 7
subunit protein.
Length = 449
Score = 91.5 bits (217), Expect = 9e-18
Identities = 67/256 (26%), Positives = 122/256 (47%), Gaps = 19/256 (7%)
Query: 232 IGSGVYGKVM-LIRSNAGKQFVAKTV----ISQYQTNSMEEYSTLRILRNTPNIVKLIEC 286
IG G + V ++ G ++ AK + +S +E + + L NIV+L +
Sbjct: 20 IGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKHSNIVRLHDS 79
Query: 287 YSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFDIKP 346
S+ V + + GG LF+ + SE D ++Q+ + + H G++H D+KP
Sbjct: 80 ISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKP 139
Query: 347 ENVMCCSLNCLN--IKIIDFGLTKCARSRTPINRNFGFFSS---VAPELYSGNVLTTAYD 401
EN++ S C +K+ DFGL + FGF + ++PE+ D
Sbjct: 140 ENLLLAS-KCKGAAVKLADFGL--AIEVQGDQQAWFGFAGTPGYLSPEVLRKEAYGKPVD 196
Query: 402 MWSVGILMGIGLLGYTP------RIIGKRSRRLSVVFTSQEYLCISGAALHFFGKCLHTN 455
+W+ G+++ I L+GY P + ++ + + F S E+ ++ A + + L N
Sbjct: 197 IWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTIN 256
Query: 456 PSRRLTAAQALNHPWM 471
P++R+TA +AL HPW+
Sbjct: 257 PAKRITAHEALKHPWV 272
>AF083419-1|AAD42038.1| 517|Homo sapiens
calcium/calmodulin-dependent protein kinase II beta e
subunit protein.
Length = 517
Score = 91.5 bits (217), Expect = 9e-18
Identities = 67/256 (26%), Positives = 122/256 (47%), Gaps = 19/256 (7%)
Query: 232 IGSGVYGKVM-LIRSNAGKQFVAKTV----ISQYQTNSMEEYSTLRILRNTPNIVKLIEC 286
IG G + V ++ G ++ AK + +S +E + + L NIV+L +
Sbjct: 20 IGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKHSNIVRLHDS 79
Query: 287 YSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFDIKP 346
S+ V + + GG LF+ + SE D ++Q+ + + H G++H D+KP
Sbjct: 80 ISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKP 139
Query: 347 ENVMCCSLNCLN--IKIIDFGLTKCARSRTPINRNFGFFSS---VAPELYSGNVLTTAYD 401
EN++ S C +K+ DFGL + FGF + ++PE+ D
Sbjct: 140 ENLLLAS-KCKGAAVKLADFGL--AIEVQGDQQAWFGFAGTPGYLSPEVLRKEAYGKPVD 196
Query: 402 MWSVGILMGIGLLGYTP------RIIGKRSRRLSVVFTSQEYLCISGAALHFFGKCLHTN 455
+W+ G+++ I L+GY P + ++ + + F S E+ ++ A + + L N
Sbjct: 197 IWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTIN 256
Query: 456 PSRRLTAAQALNHPWM 471
P++R+TA +AL HPW+
Sbjct: 257 PAKRITAHEALKHPWV 272
>AF081924-1|AAD42037.1| 492|Homo sapiens
calcium/calmodulin-dependent protein kinase II beta 6
subunit protein.
Length = 492
Score = 91.5 bits (217), Expect = 9e-18
Identities = 67/256 (26%), Positives = 122/256 (47%), Gaps = 19/256 (7%)
Query: 232 IGSGVYGKVM-LIRSNAGKQFVAKTV----ISQYQTNSMEEYSTLRILRNTPNIVKLIEC 286
IG G + V ++ G ++ AK + +S +E + + L NIV+L +
Sbjct: 20 IGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKHSNIVRLHDS 79
Query: 287 YSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFDIKP 346
S+ V + + GG LF+ + SE D ++Q+ + + H G++H D+KP
Sbjct: 80 ISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKP 139
Query: 347 ENVMCCSLNCLN--IKIIDFGLTKCARSRTPINRNFGFFSS---VAPELYSGNVLTTAYD 401
EN++ S C +K+ DFGL + FGF + ++PE+ D
Sbjct: 140 ENLLLAS-KCKGAAVKLADFGL--AIEVQGDQQAWFGFAGTPGYLSPEVLRKEAYGKPVD 196
Query: 402 MWSVGILMGIGLLGYTP------RIIGKRSRRLSVVFTSQEYLCISGAALHFFGKCLHTN 455
+W+ G+++ I L+GY P + ++ + + F S E+ ++ A + + L N
Sbjct: 197 IWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTIN 256
Query: 456 PSRRLTAAQALNHPWM 471
P++R+TA +AL HPW+
Sbjct: 257 PAKRITAHEALKHPWV 272
>AF081572-1|AAD42036.1| 503|Homo sapiens
calcium/calmodulin-dependent protein kinase II beta e'
subunit protein.
Length = 503
Score = 91.5 bits (217), Expect = 9e-18
Identities = 67/256 (26%), Positives = 122/256 (47%), Gaps = 19/256 (7%)
Query: 232 IGSGVYGKVM-LIRSNAGKQFVAKTV----ISQYQTNSMEEYSTLRILRNTPNIVKLIEC 286
IG G + V ++ G ++ AK + +S +E + + L NIV+L +
Sbjct: 20 IGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKHSNIVRLHDS 79
Query: 287 YSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFDIKP 346
S+ V + + GG LF+ + SE D ++Q+ + + H G++H D+KP
Sbjct: 80 ISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKP 139
Query: 347 ENVMCCSLNCLN--IKIIDFGLTKCARSRTPINRNFGFFSS---VAPELYSGNVLTTAYD 401
EN++ S C +K+ DFGL + FGF + ++PE+ D
Sbjct: 140 ENLLLAS-KCKGAAVKLADFGL--AIEVQGDQQAWFGFAGTPGYLSPEVLRKEAYGKPVD 196
Query: 402 MWSVGILMGIGLLGYTP------RIIGKRSRRLSVVFTSQEYLCISGAALHFFGKCLHTN 455
+W+ G+++ I L+GY P + ++ + + F S E+ ++ A + + L N
Sbjct: 197 IWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTIN 256
Query: 456 PSRRLTAAQALNHPWM 471
P++R+TA +AL HPW+
Sbjct: 257 PAKRITAHEALKHPWV 272
>AF078803-1|AAD42035.1| 542|Homo sapiens
calcium/calmodulin-dependent protein kinase II beta
subunit protein.
Length = 542
Score = 91.5 bits (217), Expect = 9e-18
Identities = 67/256 (26%), Positives = 122/256 (47%), Gaps = 19/256 (7%)
Query: 232 IGSGVYGKVM-LIRSNAGKQFVAKTV----ISQYQTNSMEEYSTLRILRNTPNIVKLIEC 286
IG G + V ++ G ++ AK + +S +E + + L NIV+L +
Sbjct: 20 IGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKHSNIVRLHDS 79
Query: 287 YSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFDIKP 346
S+ V + + GG LF+ + SE D ++Q+ + + H G++H D+KP
Sbjct: 80 ISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKP 139
Query: 347 ENVMCCSLNCLN--IKIIDFGLTKCARSRTPINRNFGFFSS---VAPELYSGNVLTTAYD 401
EN++ S C +K+ DFGL + FGF + ++PE+ D
Sbjct: 140 ENLLLAS-KCKGAAVKLADFGL--AIEVQGDQQAWFGFAGTPGYLSPEVLRKEAYGKPVD 196
Query: 402 MWSVGILMGIGLLGYTP------RIIGKRSRRLSVVFTSQEYLCISGAALHFFGKCLHTN 455
+W+ G+++ I L+GY P + ++ + + F S E+ ++ A + + L N
Sbjct: 197 IWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTIN 256
Query: 456 PSRRLTAAQALNHPWM 471
P++R+TA +AL HPW+
Sbjct: 257 PAKRITAHEALKHPWV 272
>M95936-1|AAA58364.1| 481|Homo sapiens protein serine/threonine
kinase protein.
Length = 481
Score = 91.1 bits (216), Expect = 1e-17
Identities = 63/201 (31%), Positives = 99/201 (49%), Gaps = 9/201 (4%)
Query: 225 DFLPLKLIGSGVYGKVMLIRSNAGKQFVAKTVISQYQTNSMEEYSTL----RILRNT--P 278
DF LKL+G G +GKV+L+R A ++ A ++ + + +E + R+L+NT P
Sbjct: 151 DFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQNTRHP 210
Query: 279 NIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNG 338
+ L + FVME GG LF + +E + Y ++ S L+Y+H+
Sbjct: 211 FLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEIVSALEYLHSRD 270
Query: 339 LIHFDIKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNF-GFFSSVAPELYSGNVLT 397
+++ DIK EN+M +IKI DFGL K S + F G +APE+ N
Sbjct: 271 VVYRDIKLENLMLDKDG--HIKITDFGLCKEGISDGATMKTFCGTPEYLAPEVLEDNDYG 328
Query: 398 TAYDMWSVGILMGIGLLGYTP 418
A D W +G++M + G P
Sbjct: 329 RAVDWWGLGVVMYEMMCGRLP 349
>M77198-1|AAA36585.1| 520|Homo sapiens rac protein kinase-beta
protein.
Length = 520
Score = 91.1 bits (216), Expect = 1e-17
Identities = 63/201 (31%), Positives = 99/201 (49%), Gaps = 9/201 (4%)
Query: 225 DFLPLKLIGSGVYGKVMLIRSNAGKQFVAKTVISQYQTNSMEEYSTL----RILRNT--P 278
DF LKL+G G +GKV+L+R A ++ A ++ + + +E + R+L+NT P
Sbjct: 151 DFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQNTRHP 210
Query: 279 NIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNG 338
+ L + FVME GG LF + +E + Y ++ S L+Y+H+
Sbjct: 211 FLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEIVSALEYLHSRD 270
Query: 339 LIHFDIKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNF-GFFSSVAPELYSGNVLT 397
+++ DIK EN+M +IKI DFGL K S + F G +APE+ N
Sbjct: 271 VVYRDIKLENLMLDKDG--HIKITDFGLCKEGISDGATMKTFCGTPEYLAPEVLEDNDYG 328
Query: 398 TAYDMWSVGILMGIGLLGYTP 418
A D W +G++M + G P
Sbjct: 329 RAVDWWGLGVVMYEMMCGRLP 349
>BC120994-1|AAI20995.1| 481|Homo sapiens v-akt murine thymoma viral
oncogene homolog 2 protein.
Length = 481
Score = 91.1 bits (216), Expect = 1e-17
Identities = 63/201 (31%), Positives = 99/201 (49%), Gaps = 9/201 (4%)
Query: 225 DFLPLKLIGSGVYGKVMLIRSNAGKQFVAKTVISQYQTNSMEEYSTL----RILRNT--P 278
DF LKL+G G +GKV+L+R A ++ A ++ + + +E + R+L+NT P
Sbjct: 151 DFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQNTRHP 210
Query: 279 NIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNG 338
+ L + FVME GG LF + +E + Y ++ S L+Y+H+
Sbjct: 211 FLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEIVSALEYLHSRD 270
Query: 339 LIHFDIKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNF-GFFSSVAPELYSGNVLT 397
+++ DIK EN+M +IKI DFGL K S + F G +APE+ N
Sbjct: 271 VVYRDIKLENLMLDKDG--HIKITDFGLCKEGISDGATMKTFCGTPEYLAPEVLEDNDYG 328
Query: 398 TAYDMWSVGILMGIGLLGYTP 418
A D W +G++M + G P
Sbjct: 329 RAVDWWGLGVVMYEMMCGRLP 349
>AF112472-1|AAD03744.1| 542|Homo sapiens
calcium/calmodulin-dependent protein kinase II beta
subunit protein.
Length = 542
Score = 91.1 bits (216), Expect = 1e-17
Identities = 67/256 (26%), Positives = 122/256 (47%), Gaps = 19/256 (7%)
Query: 232 IGSGVYGKVM-LIRSNAGKQFVAKTV----ISQYQTNSMEEYSTLRILRNTPNIVKLIEC 286
IG G + V ++ G ++ AK + +S +E + + L NIV+L +
Sbjct: 20 IGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLVKHSNIVRLHDS 79
Query: 287 YSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFDIKP 346
S+ V + + GG LF+ + SE D ++Q+ + + H G++H D+KP
Sbjct: 80 ISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILXAVLHCHQMGVVHRDLKP 139
Query: 347 ENVMCCSLNCLN--IKIIDFGLTKCARSRTPINRNFGFFSS---VAPELYSGNVLTTAYD 401
EN++ S C +K+ DFGL + FGF + ++PE+ D
Sbjct: 140 ENLLLAS-KCKGAAVKLADFGL--AIEVQGDQQAWFGFAGTPGYLSPEVLRKEAYGKPVD 196
Query: 402 MWSVGILMGIGLLGYTP------RIIGKRSRRLSVVFTSQEYLCISGAALHFFGKCLHTN 455
+W+ G+++ I L+GY P + ++ + + F S E+ ++ A + + L N
Sbjct: 197 IWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTIN 256
Query: 456 PSRRLTAAQALNHPWM 471
P++R+TA +AL HPW+
Sbjct: 257 PAKRITAHEALKHPWV 272
>AF112471-1|AAD03743.1| 517|Homo sapiens
calcium/calmodulin-dependent protein kinase II beta
subunit protein.
Length = 517
Score = 91.1 bits (216), Expect = 1e-17
Identities = 67/256 (26%), Positives = 122/256 (47%), Gaps = 19/256 (7%)
Query: 232 IGSGVYGKVM-LIRSNAGKQFVAKTV----ISQYQTNSMEEYSTLRILRNTPNIVKLIEC 286
IG G + V ++ G ++ AK + +S +E + + L NIV+L +
Sbjct: 20 IGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLVKHSNIVRLHDS 79
Query: 287 YSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQVCSGLQYIHNNGLIHFDIKP 346
S+ V + + GG LF+ + SE D ++Q+ + + H G++H D+KP
Sbjct: 80 ISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILXAVLHCHQMGVVHRDLKP 139
Query: 347 ENVMCCSLNCLN--IKIIDFGLTKCARSRTPINRNFGFFSS---VAPELYSGNVLTTAYD 401
EN++ S C +K+ DFGL + FGF + ++PE+ D
Sbjct: 140 ENLLLAS-KCKGAAVKLADFGL--AIEVQGDQQAWFGFAGTPGYLSPEVLRKEAYGKPVD 196
Query: 402 MWSVGILMGIGLLGYTP------RIIGKRSRRLSVVFTSQEYLCISGAALHFFGKCLHTN 455
+W+ G+++ I L+GY P + ++ + + F S E+ ++ A + + L N
Sbjct: 197 IWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTIN 256
Query: 456 PSRRLTAAQALNHPWM 471
P++R+TA +AL HPW+
Sbjct: 257 PAKRITAHEALKHPWV 272
>Y11950-1|CAA72694.1| 406|Homo sapiens phosphorylase kinase gamma
subunit protein.
Length = 406
Score = 90.2 bits (214), Expect = 2e-17
Identities = 73/293 (24%), Positives = 128/293 (43%), Gaps = 27/293 (9%)
Query: 220 QNFYRDFLPLKLIGSGVYGKVM-LIRSNAGKQFVAKTVISQYQTNSMEEYSTLR------ 272
+ FY+ + P +IG GV V + G +F K + + S E+ +R
Sbjct: 18 KEFYQKYDPKDVIGRGVSSVVRRCVHRATGHEFAVKIMEVTAERLSPEQLEEVREATRRE 77
Query: 273 --ILRNT---PNIVKLIECYSDGLNWVFVMENLWGGNLFDRFKHHQCISERDIKIYLRQV 327
ILR P+I+ LI+ Y V + + G LFD +SE++ + +R +
Sbjct: 78 THILRQVAGHPHIITLIDSYESSSFMFLVFDLMRKGELFDYLTEKVALSEKETRSIMRSL 137
Query: 328 CSGLQYIHNNGLIHFDIKPENVMCCSLNCLNIKIIDFGLTKCARSRTPINRNFGFFSSVA 387
+ ++H N ++H D+KPEN++ + + I++ DFG + + G +A
Sbjct: 138 LEAVSFLHANNIVHRDLKPENILLD--DNMQIRLSDFGFSCHLEPGEKLRELCGTPGYLA 195
Query: 388 PELYSGNVLTT------AYDMWSVGILMGIGLLGYTPRIIGKRSRRLSVV------FTSQ 435
PE+ ++ T D+W+ G+++ L G P ++ L ++ F+S
Sbjct: 196 PEILKCSMDETHPGYGKEVDLWACGVILFTLLAGSPPFWHRRQILMLRMIMEGQYQFSSP 255
Query: 436 EYLCISGAALHFFGKCLHTNPSRRLTAAQALNHPWMFDTCPHPLSWKKPSKNR 488
E+ S + L +P RLTA QAL HP+ F+ C W + R
Sbjct: 256 EWDDRSSTVKDLISRLLQVDPEARLTAEQALQHPF-FERCEGSQPWNLTPRQR 307
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.323 0.136 0.423
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 101,077,581
Number of Sequences: 224733
Number of extensions: 4224602
Number of successful extensions: 16730
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 1533
Number of HSP's successfully gapped in prelim test: 991
Number of HSP's that attempted gapping in prelim test: 11600
Number of HSP's gapped (non-prelim): 3408
length of query: 715
length of database: 73,234,838
effective HSP length: 95
effective length of query: 620
effective length of database: 51,885,203
effective search space: 32168825860
effective search space used: 32168825860
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (22.0 bits)
S2: 69 (31.9 bits)
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