Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA002079-TA|BGIBMGA002079-PA|IPR013032|EGF-like region,
IPR003961|Fibronectin, type III, IPR001660|Sterile alpha motif SAM,
IPR000719|Protein kinase, IPR008266|Tyrosine protein kinase, active
site, IPR001426|Receptor tyrosine kinase, class V, IPR001090|Ephrin
receptor, ligand binding, IPR001245|Tyrosine protein kinase,
IPR003962|Fibronectin, type III subdomain, IPR011009|Protein
kinase-like, IPR008979|Galactose-binding like, IPR008957|Fibronectin,
type III-like fold, IPR010993|Sterile alpha motif homology
(945 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q6VU50 Cluster: Eph receptor; n=3; Endopterygota|Rep: E... 1690 0.0
UniRef50_Q5D184 Cluster: Ephrin receptor; n=2; Apocrita|Rep: Eph... 1253 0.0
UniRef50_Q9V4E5 Cluster: CG1511-PC, isoform C; n=12; Diptera|Rep... 992 0.0
UniRef50_P54756 Cluster: Ephrin type-A receptor 5 precursor; n=1... 792 0.0
UniRef50_P29322 Cluster: Ephrin type-A receptor 8 precursor; n=2... 710 0.0
UniRef50_P29317 Cluster: Ephrin type-A receptor 2 precursor; n=3... 682 0.0
UniRef50_UPI0000660568 Cluster: Ephrin type-B receptor 2 precurs... 671 0.0
UniRef50_UPI000065F647 Cluster: Ephrin type-B receptor 2 precurs... 663 0.0
UniRef50_Q4H3M5 Cluster: Ephrin receptor; n=1; Ciona intestinali... 646 0.0
UniRef50_Q4SUM3 Cluster: Ephrin receptor; n=4; Tetraodon nigrovi... 632 e-179
UniRef50_UPI0000E47549 Cluster: PREDICTED: similar to Cek8; n=2;... 621 e-176
UniRef50_Q15375 Cluster: Ephrin type-A receptor 7 precursor; n=5... 550 e-155
UniRef50_P29323 Cluster: Ephrin type-B receptor 2 precursor; n=3... 543 e-153
UniRef50_Q4SWL0 Cluster: Ephrin receptor; n=3; Tetraodontidae|Re... 542 e-152
UniRef50_Q6PFV6 Cluster: Ephrin receptor; n=11; Tetrapoda|Rep: E... 521 e-146
UniRef50_Q4SQX3 Cluster: Chromosome 11 SCAF14528, whole genome s... 520 e-146
UniRef50_UPI000069DB6A Cluster: Ephrin type-A receptor 6 precurs... 519 e-145
UniRef50_Q4SFJ9 Cluster: Chromosome 7 SCAF14601, whole genome sh... 504 e-141
UniRef50_Q4T272 Cluster: Chromosome undetermined SCAF10323, whol... 489 e-136
UniRef50_Q4SC90 Cluster: Chromosome undetermined SCAF14659, whol... 482 e-134
UniRef50_Q4RXA0 Cluster: Chromosome 11 SCAF14979, whole genome s... 479 e-133
UniRef50_A2CG59 Cluster: Eph receptor B1; n=23; Euteleostomi|Rep... 477 e-133
UniRef50_Q4RV12 Cluster: Ephrin receptor; n=2; Tetraodontidae|Re... 469 e-130
UniRef50_Q4H3M4 Cluster: Ephrin receptor; n=2; Ciona intestinali... 454 e-126
UniRef50_Q4SP88 Cluster: Ephrin receptor; n=2; Tetraodon nigrovi... 451 e-125
UniRef50_Q4SMF1 Cluster: Chromosome 8 SCAF14552, whole genome sh... 444 e-123
UniRef50_Q98TD0 Cluster: Ephrin receptor; n=6; Amniota|Rep: Ephr... 441 e-122
UniRef50_UPI000065E56D Cluster: EPHB1_HUMAN Isoform 3 of P54762 ... 440 e-121
UniRef50_P21709 Cluster: Ephrin type-A receptor 1 precursor; n=1... 414 e-114
UniRef50_Q4H3M7 Cluster: Ephrin receptor; n=3; Ciona|Rep: Ephrin... 412 e-113
UniRef50_UPI000065E468 Cluster: Homolog of Gallus gallus "Ephrin... 406 e-111
UniRef50_Q9Y1Y3 Cluster: Protein tyrosine kinase; n=1; Ephydatia... 402 e-110
UniRef50_Q4H3M3 Cluster: Ephrin receptor like protein; n=1; Cion... 396 e-108
UniRef50_Q9UF33 Cluster: Ephrin type-A receptor 6 precursor; n=5... 378 e-103
UniRef50_Q5JZY3 Cluster: Ephrin type-A receptor 10 precursor; n=... 367 e-100
UniRef50_O15197 Cluster: Ephrin type-B receptor 6 precursor; n=2... 360 9e-98
UniRef50_UPI00005A2D48 Cluster: PREDICTED: similar to EPH recept... 341 7e-92
UniRef50_O61460 Cluster: Ephrin receptor 1 precursor; n=3; Caeno... 333 1e-89
UniRef50_UPI00006A241E Cluster: UPI00006A241E related cluster; n... 331 5e-89
UniRef50_UPI000065CB69 Cluster: Homolog of Homo sapiens "Ephrin ... 330 8e-89
UniRef50_Q4SFK0 Cluster: Chromosome 7 SCAF14601, whole genome sh... 314 1e-83
UniRef50_Q4RVA1 Cluster: Chromosome 15 SCAF14992, whole genome s... 310 2e-82
UniRef50_Q96HF4 Cluster: EPHA2 protein; n=3; Amniota|Rep: EPHA2 ... 308 4e-82
UniRef50_UPI000155CF4D Cluster: PREDICTED: similar to EPH recept... 303 2e-80
UniRef50_UPI000065F2B9 Cluster: Ephrin type-A receptor 8 precurs... 273 1e-71
UniRef50_Q4TFI7 Cluster: Chromosome undetermined SCAF4439, whole... 268 5e-70
UniRef50_Q4SI07 Cluster: Ephrin receptor; n=8; Clupeocephala|Rep... 260 2e-67
UniRef50_P42686 Cluster: Tyrosine-protein kinase isoform SRK1; n... 243 2e-62
UniRef50_P08631 Cluster: Tyrosine-protein kinase HCK; n=32; Eute... 241 6e-62
UniRef50_A7SFD8 Cluster: Predicted protein; n=2; Nematostella ve... 237 1e-60
UniRef50_UPI0000E814D8 Cluster: PREDICTED: similar to Ephrin typ... 236 2e-60
UniRef50_Q66I04 Cluster: Zgc:92124; n=1; Danio rerio|Rep: Zgc:92... 233 2e-59
UniRef50_P07947 Cluster: Proto-oncogene tyrosine-protein kinase ... 233 2e-59
UniRef50_Q7QAK4 Cluster: ENSANGP00000020257; n=1; Anopheles gamb... 232 4e-59
UniRef50_P42685 Cluster: Tyrosine-protein kinase FRK; n=27; Fung... 227 8e-58
UniRef50_P18106 Cluster: Tyrosine-protein kinase Fps85D; n=12; E... 227 8e-58
UniRef50_Q2VXS7 Cluster: Proto-oncogene c-fes variant 4; n=77; E... 224 8e-57
UniRef50_P00522 Cluster: Tyrosine-protein kinase Abl; n=5; Eumet... 221 5e-56
UniRef50_UPI00015B4B0F Cluster: PREDICTED: similar to proto-onco... 220 2e-55
UniRef50_UPI0000519AF4 Cluster: PREDICTED: similar to Abl tyrosi... 220 2e-55
UniRef50_Q05397 Cluster: Focal adhesion kinase 1; n=111; Euteleo... 220 2e-55
UniRef50_Q573B4 Cluster: Proto-oncogene tyrosine-protein kinase ... 218 5e-55
UniRef50_Q24488 Cluster: Tyrosine-protein kinase transmembrane r... 218 5e-55
UniRef50_Q8T6F8 Cluster: SRC-1; n=3; Caenorhabditis|Rep: SRC-1 -... 218 7e-55
UniRef50_P16591 Cluster: Proto-oncogene tyrosine-protein kinase ... 217 9e-55
UniRef50_Q70DV1 Cluster: Src tyrosine kinase; n=1; Schistosoma m... 216 3e-54
UniRef50_Q9Y1Z0 Cluster: Protein tyrosine kinase; n=1; Ephydatia... 215 4e-54
UniRef50_Q8WPV5 Cluster: Tyrosine kinase; n=2; Eumetazoa|Rep: Ty... 215 4e-54
UniRef50_Q9NH62 Cluster: Tyrosine kinase 5; n=2; Schistosoma man... 215 5e-54
UniRef50_Q6R1Y3 Cluster: Src family kinase; n=6; Fungi/Metazoa g... 215 5e-54
UniRef50_P42680 Cluster: Tyrosine-protein kinase Tec; n=86; Coel... 215 5e-54
UniRef50_Q7Q5T3 Cluster: Tyrosine-protein kinase receptor; n=3; ... 215 6e-54
UniRef50_Q17C76 Cluster: Focal adhesion kinase; n=2; Culicidae|R... 214 1e-53
UniRef50_P00519 Cluster: Proto-oncogene tyrosine-protein kinase ... 213 1e-53
UniRef50_UPI0000D577C3 Cluster: PREDICTED: similar to CG8874-PB,... 213 2e-53
UniRef50_P00521 Cluster: Tyrosine-protein kinase transforming pr... 212 3e-53
UniRef50_Q5IJ68 Cluster: Trk-like receptor tyrosine kinase; n=1;... 212 4e-53
UniRef50_UPI0000F1EB7D Cluster: PREDICTED: hypothetical protein;... 211 6e-53
UniRef50_P10447 Cluster: Tyrosine-protein kinase transforming pr... 211 8e-53
UniRef50_Q7YZX2 Cluster: Bruton's tyrosine kinase-like protein; ... 210 1e-52
UniRef50_P51451 Cluster: Tyrosine-protein kinase BLK; n=5; Eutel... 210 1e-52
UniRef50_Q4S351 Cluster: Chromosome 4 SCAF14752, whole genome sh... 210 1e-52
UniRef50_Q9Y1Y2 Cluster: Protein tyrosine kinase; n=1; Ephydatia... 210 1e-52
UniRef50_O76978 Cluster: Tyrosine kinase; n=1; Sycon raphanus|Re... 210 2e-52
UniRef50_Q16XX9 Cluster: Tyrosine-protein kinase shark; n=2; Cul... 209 3e-52
UniRef50_Q06187 Cluster: Tyrosine-protein kinase BTK; n=54; Gnat... 209 3e-52
UniRef50_P03949 Cluster: Tyrosine-protein kinase abl-1; n=5; Cae... 209 3e-52
UniRef50_Q5MCM8 Cluster: Protein-tyrosine kinase; n=2; Anthomedu... 208 5e-52
UniRef50_Q52V39 Cluster: Tyrosine-protein kinase receptor; n=2; ... 207 1e-51
UniRef50_Q170Z1 Cluster: Tyrosine-protein kinase receptor; n=1; ... 207 1e-51
UniRef50_P00528 Cluster: Tyrosine-protein kinase Src64B; n=6; En... 206 2e-51
UniRef50_Q7Z1D3 Cluster: Focal adhesion kinase; n=1; Lytechinus ... 206 3e-51
UniRef50_O77440 Cluster: Protein-tyrosine kinase HTK98; n=1; Hyd... 206 3e-51
UniRef50_UPI0000D569CE Cluster: PREDICTED: similar to CG10023-PA... 205 4e-51
UniRef50_UPI00015A7C25 Cluster: UPI00015A7C25 related cluster; n... 205 4e-51
UniRef50_Q4RY69 Cluster: Chromosome 3 SCAF14978, whole genome sh... 205 5e-51
UniRef50_Q9Y1Y9 Cluster: Protein tyrosine kinase; n=3; Metazoa|R... 205 5e-51
UniRef50_Q9Y1Y6 Cluster: Protein tyrosine kinase; n=1; Ephydatia... 205 5e-51
UniRef50_Q9Y1Y1 Cluster: Protein tyrosine kinase; n=2; cellular ... 205 5e-51
UniRef50_Q0PDJ5 Cluster: Protein tyrosine kinase CSK; n=1; Monos... 205 5e-51
UniRef50_P08922 Cluster: Proto-oncogene tyrosine-protein kinase ... 204 7e-51
UniRef50_Q7YZH7 Cluster: MBRTK2; n=1; Monosiga brevicollis|Rep: ... 204 9e-51
UniRef50_Q8WRF4 Cluster: Receptor tyrosine kinase; n=1; Monosiga... 203 2e-50
UniRef50_Q14289 Cluster: Protein tyrosine kinase 2 beta; n=47; E... 203 2e-50
UniRef50_P42684 Cluster: Tyrosine-protein kinase ABL2; n=38; Eut... 203 2e-50
UniRef50_Q7YSY1 Cluster: Fes-like tyrosine kinase protein; n=1; ... 202 3e-50
UniRef50_Q16620 Cluster: BDNF/NT-3 growth factors receptor precu... 202 3e-50
UniRef50_P43403 Cluster: Tyrosine-protein kinase ZAP-70; n=55; E... 202 4e-50
UniRef50_UPI0000DB7330 Cluster: PREDICTED: similar to Ack CG1499... 202 5e-50
UniRef50_Q9U531 Cluster: Focal adhesion kinase homolog DFak56; n... 202 5e-50
UniRef50_Q4H3N2 Cluster: Epidermal growth factor receptor; n=1; ... 202 5e-50
UniRef50_P41240 Cluster: Tyrosine-protein kinase CSK; n=21; Deut... 202 5e-50
UniRef50_Q9H3Y6 Cluster: Tyrosine-protein kinase Srms; n=17; Amn... 201 6e-50
UniRef50_Q01973 Cluster: Tyrosine-protein kinase transmembrane r... 201 6e-50
UniRef50_Q91987 Cluster: BDNF/NT-3 growth factors receptor precu... 201 8e-50
UniRef50_Q08881 Cluster: Tyrosine-protein kinase ITK/TSK; n=18; ... 201 8e-50
UniRef50_P08630 Cluster: Tyrosine-protein kinase Btk29A; n=10; E... 200 1e-49
UniRef50_UPI00015A61DF Cluster: UPI00015A61DF related cluster; n... 200 1e-49
UniRef50_O76148 Cluster: Tyrosine-protein kinase receptor; n=1; ... 200 1e-49
UniRef50_UPI0000F1FB23 Cluster: PREDICTED: similar to tyrosine p... 199 2e-49
UniRef50_P00529 Cluster: Tyrosine-protein kinase transforming pr... 198 4e-49
UniRef50_Q01974 Cluster: Tyrosine-protein kinase transmembrane r... 198 4e-49
UniRef50_UPI00015B5971 Cluster: PREDICTED: similar to leukocyte ... 198 6e-49
UniRef50_UPI0000E48523 Cluster: PREDICTED: similar to protein-ty... 198 6e-49
UniRef50_A7RHT9 Cluster: Predicted protein; n=1; Nematostella ve... 198 6e-49
UniRef50_UPI00015B5A01 Cluster: PREDICTED: similar to protein ki... 198 8e-49
UniRef50_Q910A2 Cluster: Spleen protein tyrosine kinase; n=2; Da... 197 1e-48
UniRef50_Q4H3B8 Cluster: Tyrosine-protein kinase receptor; n=1; ... 197 1e-48
UniRef50_P04629 Cluster: High affinity nerve growth factor recep... 197 1e-48
UniRef50_Q4T351 Cluster: Chromosome undetermined SCAF10118, whol... 196 2e-48
UniRef50_Q9BKL8 Cluster: Tyrosine-protein kinase receptor; n=2; ... 196 2e-48
UniRef50_Q5TUS8 Cluster: Tyrosine-protein kinase receptor; n=1; ... 196 2e-48
UniRef50_Q25410 Cluster: Putative molluscan insulin-related pept... 196 3e-48
UniRef50_UPI0000DB7F8D Cluster: PREDICTED: similar to Cad96Ca CG... 195 4e-48
UniRef50_UPI0000DB6D22 Cluster: PREDICTED: similar to Alk CG8250... 195 4e-48
UniRef50_UPI0000D57520 Cluster: PREDICTED: similar to CG8250-PA;... 195 4e-48
UniRef50_UPI00006A20DD Cluster: UPI00006A20DD related cluster; n... 195 4e-48
UniRef50_Q4SK07 Cluster: Tyrosine-protein kinase receptor; n=2; ... 195 4e-48
UniRef50_Q12866 Cluster: Proto-oncogene tyrosine-protein kinase ... 195 4e-48
UniRef50_Q9PVZ4 Cluster: Insulin receptor precursor (EC 2.7.10.1... 195 4e-48
UniRef50_Q9Y1X9 Cluster: Protein tyrosine kinase; n=1; Ephydatia... 194 7e-48
UniRef50_UPI000065F6B2 Cluster: Receptor tyrosine-protein kinase... 194 9e-48
UniRef50_Q8JFV0 Cluster: Tyrosine-protein kinase receptor; n=5; ... 194 9e-48
UniRef50_Q9Y1Y0 Cluster: Protein tyrosine kinase; n=1; Ephydatia... 194 9e-48
UniRef50_Q9BL77 Cluster: C-terminal src kinase protein 1; n=2; C... 194 9e-48
UniRef50_Q8INU0 Cluster: CG14396-PD, isoform D; n=10; Sophophora... 194 9e-48
UniRef50_P53356 Cluster: Tyrosine-protein kinase HTK16; n=1; Hyd... 194 9e-48
UniRef50_Q15303 Cluster: Receptor tyrosine-protein kinase erbB-4... 194 9e-48
UniRef50_A6P4V4 Cluster: Tyrosine-protein kinase receptor; n=2; ... 194 1e-47
UniRef50_P51813 Cluster: Cytoplasmic tyrosine-protein kinase BMX... 194 1e-47
UniRef50_Q9UM73 Cluster: ALK tyrosine kinase receptor precursor;... 194 1e-47
UniRef50_UPI00015B51DA Cluster: PREDICTED: similar to ENSANGP000... 193 2e-47
UniRef50_UPI0000F2052A Cluster: PREDICTED: similar to anaplastic... 193 2e-47
UniRef50_Q4SS18 Cluster: Chromosome undetermined SCAF14482, whol... 193 2e-47
UniRef50_Q9Y1X8 Cluster: Protein tyrosine kinase; n=1; Ephydatia... 193 2e-47
UniRef50_Q7YT64 Cluster: Tyrosine-protein kinase receptor; n=1; ... 193 2e-47
UniRef50_Q2LC18 Cluster: Tyrosine-protein kinase receptor; n=2; ... 193 2e-47
UniRef50_O77132 Cluster: Non-receptor protein-tyrosine kinase CS... 193 2e-47
UniRef50_P06213 Cluster: Insulin receptor precursor (EC 2.7.10.1... 193 2e-47
UniRef50_UPI0000DB6DD4 Cluster: PREDICTED: similar to Insulin-li... 193 2e-47
UniRef50_P04626 Cluster: Receptor tyrosine-protein kinase erbB-2... 193 2e-47
UniRef50_UPI0000DB6C99 Cluster: PREDICTED: similar to proto-onco... 192 3e-47
UniRef50_Q60I21 Cluster: TEC family protein tyrosine kinase; n=1... 192 3e-47
UniRef50_O73798 Cluster: Insulin-like growth factor 1 receptor p... 192 3e-47
UniRef50_UPI0000E4736E Cluster: PREDICTED: similar to src-family... 192 4e-47
UniRef50_UPI0000D5603D Cluster: PREDICTED: similar to Insulin re... 192 4e-47
UniRef50_Q08BY6 Cluster: Zgc:153964; n=3; Danio rerio|Rep: Zgc:1... 192 4e-47
UniRef50_P08069 Cluster: Insulin-like growth factor 1 receptor p... 192 4e-47
UniRef50_Q16832 Cluster: Discoidin domain-containing receptor 2 ... 192 4e-47
UniRef50_UPI0000D55B96 Cluster: PREDICTED: similar to Tyrosine-p... 192 5e-47
UniRef50_Q8JG38 Cluster: Fibroblast growth factor receptor 2 pre... 192 5e-47
UniRef50_A3EXK5 Cluster: Fibroblast growth factor receptor b; n=... 191 7e-47
UniRef50_P00534 Cluster: Tyrosine-protein kinase transforming pr... 191 7e-47
UniRef50_Q7PYY7 Cluster: ENSANGP00000019144; n=1; Anopheles gamb... 191 9e-47
UniRef50_P00533 Cluster: Epidermal growth factor receptor precur... 191 9e-47
UniRef50_Q9VBW3 Cluster: Tyrosine kinase receptor Cad96Ca precur... 191 9e-47
UniRef50_UPI00004D7E5F Cluster: Proto-oncogene tyrosine-protein ... 190 1e-46
UniRef50_UPI0000D56EE8 Cluster: PREDICTED: similar to CG14992-PA... 190 2e-46
UniRef50_Q17MF5 Cluster: Tyrosine-protein kinase; n=2; Culicidae... 190 2e-46
UniRef50_P08923 Cluster: Leukocyte tyrosine kinase receptor prec... 190 2e-46
UniRef50_Q4SII9 Cluster: Chromosome 5 SCAF14581, whole genome sh... 190 2e-46
UniRef50_Q5K4G5 Cluster: Receptor tyrosine kinase; n=1; Suberite... 190 2e-46
UniRef50_Q008W6 Cluster: Gamma-carboxyglutamic acid protein 1; n... 190 2e-46
UniRef50_P42679 Cluster: Megakaryocyte-associated tyrosine-prote... 190 2e-46
UniRef50_Q6NP28 Cluster: LP09923p; n=6; Endopterygota|Rep: LP099... 189 4e-46
UniRef50_Q9XVQ7 Cluster: Putative uncharacterized protein; n=2; ... 188 5e-46
UniRef50_UPI00015B6133 Cluster: PREDICTED: similar to protein ty... 188 6e-46
UniRef50_UPI00004D86FC Cluster: Tyrosine-protein kinase Tec (EC ... 188 6e-46
UniRef50_Q16UV1 Cluster: Protein kinase protein; n=3; Culicidae|... 188 6e-46
UniRef50_Q8IXC7 Cluster: Isoform of FGFR2; n=23; Euteleostomi|Re... 188 6e-46
UniRef50_UPI0000ECD739 Cluster: Cytoplasmic tyrosine-protein kin... 188 8e-46
UniRef50_UPI00015B5959 Cluster: PREDICTED: similar to insulin re... 187 1e-45
UniRef50_A6NNJ8 Cluster: Uncharacterized protein LTK; n=12; Euar... 187 1e-45
UniRef50_P43405 Cluster: Tyrosine-protein kinase SYK; n=23; Ther... 187 1e-45
UniRef50_A7SZN9 Cluster: Predicted protein; n=3; Nematostella ve... 187 1e-45
UniRef50_A7RNB1 Cluster: Predicted protein; n=1; Nematostella ve... 187 1e-45
UniRef50_UPI0000DB7735 Cluster: PREDICTED: similar to Insulin re... 186 2e-45
UniRef50_Q7KJ08 Cluster: Receptor protein tyrosine kinase ALK sp... 186 2e-45
UniRef50_UPI0000D57178 Cluster: PREDICTED: similar to CG14396-PA... 186 2e-45
UniRef50_A7RGW8 Cluster: Predicted protein; n=1; Nematostella ve... 186 2e-45
UniRef50_O76997 Cluster: Putative neurotrophin receptor LTRK 1 p... 186 2e-45
UniRef50_Q13882 Cluster: Tyrosine-protein kinase 6; n=11; Mammal... 186 2e-45
UniRef50_UPI0000E49FB6 Cluster: PREDICTED: similar to RE05926p, ... 186 3e-45
UniRef50_P42687 Cluster: Tyrosine-protein kinase SPK-1; n=1; Gir... 186 3e-45
UniRef50_O15146 Cluster: Muscle, skeletal receptor tyrosine prot... 185 4e-45
UniRef50_Q9YI66 Cluster: Developmental receptor tyrosine kinase;... 185 6e-45
UniRef50_P04412 Cluster: Epidermal growth factor receptor precur... 185 6e-45
UniRef50_UPI0000E47068 Cluster: PREDICTED: similar to tyrosine p... 184 8e-45
UniRef50_Q9YGM5 Cluster: Plasminogen related growth factor recep... 184 8e-45
UniRef50_Q9U5A8 Cluster: Insulin receptor-like protein precursor... 184 8e-45
UniRef50_UPI0000D57699 Cluster: PREDICTED: similar to CG18247-PA... 184 1e-44
UniRef50_UPI0000D57494 Cluster: PREDICTED: similar to insulin re... 184 1e-44
UniRef50_Q07912 Cluster: Activated CDC42 kinase 1; n=24; Euteleo... 184 1e-44
UniRef50_O02742 Cluster: Activated CDC42 kinase 2; n=13; Euteleo... 183 2e-44
UniRef50_Q24145 Cluster: Tyrosine-protein kinase shark; n=2; Sop... 183 2e-44
UniRef50_P08581 Cluster: Hepatocyte growth factor receptor precu... 183 2e-44
UniRef50_Q86PM4 Cluster: Fibroblast growth factor receptor precu... 183 2e-44
UniRef50_UPI000051AB92 Cluster: PREDICTED: similar to Fak-like t... 182 3e-44
UniRef50_O97191 Cluster: Tyrosine-protein kinase receptor; n=1; ... 182 3e-44
UniRef50_P23049 Cluster: Tyrosine-protein kinase transforming pr... 182 3e-44
UniRef50_A7RL50 Cluster: Predicted protein; n=1; Nematostella ve... 182 4e-44
UniRef50_A0JMM7 Cluster: Zgc:154019; n=2; Danio rerio|Rep: Zgc:1... 182 5e-44
UniRef50_A3EXK6 Cluster: Fibroblast growth factor receptor c; n=... 182 5e-44
UniRef50_Q8AXY6 Cluster: Muscle, skeletal receptor tyrosine prot... 182 5e-44
UniRef50_P11362 Cluster: Basic fibroblast growth factor receptor... 182 5e-44
UniRef50_UPI00015B4221 Cluster: PREDICTED: similar to tyrosine-p... 181 7e-44
UniRef50_A7RZ71 Cluster: Predicted protein; n=1; Nematostella ve... 181 7e-44
UniRef50_Q02763 Cluster: Angiopoietin-1 receptor precursor; n=41... 181 7e-44
UniRef50_Q9V6K3 Cluster: Tyrosine-protein kinase transmembrane r... 181 7e-44
UniRef50_UPI00015B4CAE Cluster: PREDICTED: similar to ENSANGP000... 181 9e-44
UniRef50_UPI0000DB6B52 Cluster: PREDICTED: similar to Ror CG4926... 181 9e-44
UniRef50_P79950 Cluster: Tyrosine kinase receptor; n=3; Xenopus|... 181 9e-44
UniRef50_Q7Q0F6 Cluster: Tyrosine-protein kinase receptor; n=2; ... 181 9e-44
UniRef50_Q7PWP1 Cluster: ENSANGP00000013218; n=2; Culicidae|Rep:... 181 9e-44
UniRef50_P35590 Cluster: Tyrosine-protein kinase receptor Tie-1 ... 181 9e-44
UniRef50_P13368 Cluster: Protein sevenless; n=20; Eumetazoa|Rep:... 181 9e-44
UniRef50_Q9VZI2 Cluster: CG14992-PA; n=3; Sophophora|Rep: CG1499... 180 1e-43
UniRef50_Q4H3N3 Cluster: Epidermal growth factor receptor; n=1; ... 180 1e-43
UniRef50_P30530 Cluster: Tyrosine-protein kinase receptor UFO pr... 180 1e-43
UniRef50_UPI0000E47617 Cluster: PREDICTED: similar to muscle spe... 180 2e-43
UniRef50_UPI0000D55449 Cluster: PREDICTED: similar to CG7223-PA,... 180 2e-43
UniRef50_Q17JW1 Cluster: Tyrosine protein kinase; n=2; Culicidae... 180 2e-43
UniRef50_Q59F30 Cluster: Fibroblast growth factor receptor 4 var... 180 2e-43
UniRef50_Q3TJ05 Cluster: 14 days pregnant adult female placenta ... 179 3e-43
UniRef50_Q5RIU8 Cluster: Novel protein similar to vertebrate dis... 179 4e-43
UniRef50_Q17J18 Cluster: Tyrosine-protein kinase; n=4; Endoptery... 178 5e-43
UniRef50_Q06418 Cluster: Tyrosine-protein kinase receptor TYRO3 ... 178 5e-43
UniRef50_Q64GK4 Cluster: C-Met receptor tyrosine kinase; n=9; Cl... 178 7e-43
UniRef50_Q1JUB8 Cluster: Fibroblast growth factor receptor; n=2;... 178 7e-43
UniRef50_Q93105 Cluster: Insulin-like receptor precursor (EC 2.7... 178 7e-43
UniRef50_P22182 Cluster: Fibroblast growth factor receptor 1 pre... 178 7e-43
UniRef50_Q4RPK6 Cluster: Chromosome 12 SCAF15007, whole genome s... 177 9e-43
UniRef50_Q4RJ67 Cluster: Chromosome 1 SCAF15039, whole genome sh... 177 9e-43
UniRef50_Q17LF1 Cluster: Muscle-specific tyrosine kinase recepto... 177 9e-43
UniRef50_A3EXK4 Cluster: Fibroblast growth factor receptor a; n=... 177 9e-43
UniRef50_UPI0000D56AE3 Cluster: PREDICTED: similar to CG1594-PA;... 177 1e-42
UniRef50_UPI0000D563AD Cluster: PREDICTED: similar to CG3969-PA,... 177 1e-42
UniRef50_UPI0000D55DFF Cluster: PREDICTED: similar to Insulin-li... 177 1e-42
UniRef50_Q4SQ93 Cluster: Tyrosine-protein kinase receptor; n=2; ... 177 1e-42
UniRef50_Q08345 Cluster: Epithelial discoidin domain-containing ... 177 1e-42
UniRef50_Q26614 Cluster: Fibroblast growth factor receptor precu... 177 2e-42
UniRef50_Q95YD4 Cluster: Protein kinase protein 32, isoform a; n... 176 2e-42
UniRef50_Q03142 Cluster: Fibroblast growth factor receptor 4 pre... 176 2e-42
UniRef50_Q4S1S8 Cluster: Chromosome undetermined SCAF14764, whol... 176 3e-42
UniRef50_P07949 Cluster: Proto-oncogene tyrosine-protein kinase ... 176 3e-42
UniRef50_P09208 Cluster: Insulin-like receptor precursor (EC 2.7... 176 3e-42
UniRef50_Q6SAJ2 Cluster: Epidermal growth factor receptor; n=11;... 175 4e-42
UniRef50_Q2VJ45 Cluster: HOOK3-RET fusion protein; n=3; Eutheria... 175 5e-42
UniRef50_Q86MD7 Cluster: EGF receptor; n=1; Echinococcus multilo... 175 6e-42
UniRef50_P14616 Cluster: Insulin receptor-related protein precur... 175 6e-42
UniRef50_UPI0000E47C0F Cluster: PREDICTED: similar to focal adhe... 174 8e-42
UniRef50_Q4TEC1 Cluster: Chromosome undetermined SCAF5507, whole... 174 1e-41
UniRef50_UPI0000E471D0 Cluster: PREDICTED: similar to p80 protei... 173 1e-41
UniRef50_Q0P4R9 Cluster: Discoidin domain receptor family, membe... 173 1e-41
UniRef50_Q179Z3 Cluster: Tyrosine-protein kinase; n=1; Aedes aeg... 173 1e-41
UniRef50_Q24592 Cluster: Tyrosine-protein kinase hopscotch; n=2;... 173 1e-41
UniRef50_UPI000065FEDC Cluster: Activated CDC42 kinase 1 (EC 2.7... 173 2e-41
UniRef50_Q9GRH2 Cluster: Tyrosine-protein kinase receptor; n=1; ... 173 2e-41
UniRef50_Q9BLY1 Cluster: Receptor tyrosine kinase; n=5; Caenorha... 172 3e-41
UniRef50_UPI00015B6363 Cluster: PREDICTED: similar to tyrosine p... 172 4e-41
UniRef50_Q7Z1L9 Cluster: Neurite outgrowth regulated kinase; n=1... 172 4e-41
UniRef50_O45232 Cluster: Putative uncharacterized protein ark-1;... 171 6e-41
UniRef50_Q25177 Cluster: Receptor protein-tyrosine kinase; n=2; ... 171 1e-40
UniRef50_UPI0000DB7B4C Cluster: PREDICTED: similar to hopscotch ... 170 1e-40
UniRef50_A7SAX2 Cluster: Predicted protein; n=3; Nematostella ve... 170 1e-40
UniRef50_Q5BXN9 Cluster: SJCHGC05493 protein; n=1; Schistosoma j... 170 2e-40
UniRef50_Q8MY86 Cluster: Fibroblast growth factor receptor 1 pre... 170 2e-40
UniRef50_Q4TBR4 Cluster: Chromosome undetermined SCAF7099, whole... 169 2e-40
UniRef50_Q7PT15 Cluster: ENSANGP00000009263; n=2; Culicidae|Rep:... 169 2e-40
UniRef50_Q6SAA3 Cluster: Epidermal growth factor receptor; n=39;... 169 2e-40
UniRef50_UPI000065E2FA Cluster: Homolog of Homo sapiens "Tyrosin... 169 3e-40
UniRef50_Q4SR43 Cluster: Chromosome 11 SCAF14528, whole genome s... 169 3e-40
UniRef50_UPI00006A1E7A Cluster: Non-receptor tyrosine-protein ki... 168 5e-40
UniRef50_Q04912 Cluster: Macrophage-stimulating protein receptor... 168 5e-40
UniRef50_Q5I4E2 Cluster: Bm-DAF-2 precursor; n=1; Brugia malayi|... 167 9e-40
UniRef50_Q6DTW4 Cluster: Tyrosine kinase receptor ron; n=6; Eume... 167 1e-39
UniRef50_Q9Y1Y5 Cluster: Protein tyrosine kinase; n=1; Ephydatia... 167 1e-39
UniRef50_O76411 Cluster: Suppressor of constitutive dauer format... 167 1e-39
UniRef50_UPI000065F9C5 Cluster: Epithelial discoidin domain-cont... 166 2e-39
UniRef50_Q4RL31 Cluster: Chromosome undetermined SCAF15024, whol... 165 5e-39
UniRef50_Q09147 Cluster: Fibroblast growth factor receptor homol... 165 5e-39
UniRef50_Q7YXV8 Cluster: Protein tyrosine kinase; n=1; Ephydatia... 165 7e-39
UniRef50_Q8NFA8 Cluster: Transmembrane receptor PTK7-2; n=18; Eu... 165 7e-39
UniRef50_Q13308 Cluster: Tyrosine-protein kinase-like 7 precurso... 165 7e-39
UniRef50_Q9Y1Y8 Cluster: Protein tyrosine kinase; n=2; Metazoa|R... 164 9e-39
UniRef50_Q70W11 Cluster: Receptor tyrosine kinase X; n=1; Ciona ... 164 9e-39
UniRef50_UPI0000E48069 Cluster: PREDICTED: hypothetical protein;... 164 1e-38
UniRef50_Q95ZV7 Cluster: Putative uncharacterized protein; n=3; ... 163 2e-38
UniRef50_Q5G254 Cluster: Erbb3; n=6; Danio rerio|Rep: Erbb3 - Da... 163 2e-38
UniRef50_P24348 Cluster: Receptor tyrosine-protein kinase let-23... 163 3e-38
UniRef50_Q4S1M5 Cluster: Chromosome 6 SCAF14768, whole genome sh... 162 4e-38
UniRef50_Q61B52 Cluster: Putative uncharacterized protein CBG134... 162 4e-38
UniRef50_Q26566 Cluster: Epidermal growth factor receptor precur... 162 4e-38
UniRef50_O17391 Cluster: Protein kinase protein 9, isoform b; n=... 162 4e-38
UniRef50_A7SE14 Cluster: Predicted protein; n=4; Nematostella ve... 162 4e-38
UniRef50_A7RGV3 Cluster: Predicted protein; n=1; Nematostella ve... 162 5e-38
UniRef50_Q10925-2 Cluster: Isoform b of Q10925 ; n=2; Caenorhabd... 161 6e-38
UniRef50_Q9Y1Y7 Cluster: Protein tyrosine kinase; n=1; Ephydatia... 161 6e-38
UniRef50_Q17HL3 Cluster: Discoidin domain receptor; n=3; Culicid... 161 6e-38
UniRef50_Q10925 Cluster: Probable tyrosine-protein kinase kin-25... 161 6e-38
UniRef50_Q07407 Cluster: Fibroblast growth factor receptor homol... 161 6e-38
UniRef50_Q9N3S5 Cluster: Putative uncharacterized protein; n=4; ... 161 8e-38
UniRef50_Q7YZW6 Cluster: Putative uncharacterized protein; n=3; ... 161 8e-38
UniRef50_Q674V1 Cluster: Vascular endothelial growth factor rece... 161 8e-38
UniRef50_UPI00015A3FB5 Cluster: hypothetical protein LOC553690; ... 160 1e-37
UniRef50_Q86LZ8 Cluster: Insulin receptor protein kinase; n=2; S... 160 1e-37
UniRef50_Q13470 Cluster: Non-receptor tyrosine-protein kinase TN... 160 1e-37
UniRef50_Q25197 Cluster: Putative insulin-like peptide receptor ... 160 2e-37
UniRef50_Q68KJ7 Cluster: HER2; n=3; Amniota|Rep: HER2 - Felis si... 159 2e-37
UniRef50_Q8WSM2 Cluster: Receptor tyrosine kinase; n=1; Schistos... 159 2e-37
UniRef50_Q70W09 Cluster: Receptor tyrosine kinase VIII; n=1; Cio... 159 3e-37
UniRef50_A7SL46 Cluster: Predicted protein; n=2; Eumetazoa|Rep: ... 159 3e-37
UniRef50_A1IKE0 Cluster: Receptor tyrosine kinase-like orphan re... 159 3e-37
UniRef50_Q9XYS4 Cluster: Tyrosine kinase receptor HTK32; n=1; Hy... 159 4e-37
UniRef50_Q7YZH5 Cluster: MBTK3; n=1; Monosiga brevicollis|Rep: M... 159 4e-37
UniRef50_Q6W5B1 Cluster: TEL/JAK2 fusion protein; n=4; Danio rer... 157 1e-36
UniRef50_Q6SAW1 Cluster: Epidermal growth factor receptor; n=70;... 157 2e-36
UniRef50_P23458 Cluster: Tyrosine-protein kinase JAK1; n=55; Eut... 157 2e-36
UniRef50_Q4SF69 Cluster: Chromosome undetermined SCAF14608, whol... 156 2e-36
UniRef50_P21860 Cluster: Receptor tyrosine-protein kinase erbB-3... 156 3e-36
UniRef50_Q59DZ7 Cluster: CG33531-PA; n=6; Sophophora|Rep: CG3353... 155 4e-36
UniRef50_Q20933 Cluster: Putative uncharacterized protein; n=1; ... 153 2e-35
UniRef50_UPI00015B6067 Cluster: PREDICTED: similar to tyrosine p... 153 3e-35
UniRef50_A7S5K7 Cluster: Predicted protein; n=1; Nematostella ve... 153 3e-35
UniRef50_Q4RXB0 Cluster: Chromosome 11 SCAF14979, whole genome s... 152 4e-35
UniRef50_Q4RQT4 Cluster: Chromosome 2 SCAF15004, whole genome sh... 152 4e-35
UniRef50_Q9TX48 Cluster: 220 kDa ABL-related protein tyrosine ki... 152 4e-35
UniRef50_Q70W05 Cluster: Src protein; n=1; Ciona intestinalis|Re... 152 5e-35
UniRef50_Q25198 Cluster: Receptor tyrosine kinase 90; n=1; Hydra... 152 5e-35
UniRef50_UPI0000E257E1 Cluster: PREDICTED: similar to tyrosine k... 150 2e-34
UniRef50_Q22489 Cluster: Putative uncharacterized protein; n=4; ... 150 2e-34
UniRef50_A7SAX6 Cluster: Predicted protein; n=2; Nematostella ve... 150 2e-34
UniRef50_P04049 Cluster: RAF proto-oncogene serine/threonine-pro... 149 3e-34
UniRef50_A7RVU0 Cluster: Predicted protein; n=1; Nematostella ve... 149 3e-34
UniRef50_Q8MY85 Cluster: Fibroblast growth factor receptor 2 pre... 149 3e-34
UniRef50_UPI0000E48358 Cluster: PREDICTED: hypothetical protein;... 149 5e-34
UniRef50_Q27HR1 Cluster: Ret tyrosine-kinase receptor; n=1; Bran... 149 5e-34
UniRef50_Q23554 Cluster: Putative uncharacterized protein; n=1; ... 149 5e-34
UniRef50_Q9I9L1 Cluster: Arg protein-tyrosine kinase; n=12; Tetr... 148 6e-34
UniRef50_Q5Z986 Cluster: EDR1-like; n=3; Magnoliophyta|Rep: EDR1... 148 6e-34
UniRef50_A7S4Y9 Cluster: Predicted protein; n=1; Nematostella ve... 148 6e-34
UniRef50_Q4T1R9 Cluster: Chromosome 4 SCAF10492, whole genome sh... 148 8e-34
UniRef50_Q16RK6 Cluster: Receptor protein tyrosine kinase; n=1; ... 148 8e-34
UniRef50_UPI00006A26D5 Cluster: UPI00006A26D5 related cluster; n... 147 1e-33
UniRef50_Q9TYX4 Cluster: Putative uncharacterized protein R11E3.... 147 1e-33
UniRef50_UPI0000E47A46 Cluster: PREDICTED: similar to ret protei... 146 2e-33
UniRef50_O12990 Cluster: Tyrosine-protein kinase Jak1; n=8; Eute... 146 2e-33
UniRef50_Q4RU24 Cluster: Chromosome 12 SCAF14996, whole genome s... 146 2e-33
UniRef50_Q4SMB8 Cluster: Chromosome 3 SCAF14553, whole genome sh... 146 3e-33
UniRef50_A4RXI8 Cluster: Predicted protein; n=2; Ostreococcus|Re... 146 3e-33
UniRef50_A7S934 Cluster: Predicted protein; n=4; Nematostella ve... 146 3e-33
UniRef50_A7RNB2 Cluster: Predicted protein; n=1; Nematostella ve... 146 3e-33
UniRef50_Q5DM52 Cluster: Receptor tyrosine kinase Torso-like pro... 145 6e-33
UniRef50_Q0MQ66 Cluster: Putative uncharacterized protein; n=5; ... 144 8e-33
UniRef50_Q4RWP2 Cluster: Tyrosine-protein kinase receptor; n=1; ... 144 1e-32
UniRef50_Q6SAX5 Cluster: Epidermal growth factor receptor; n=14;... 144 1e-32
UniRef50_O76385 Cluster: Putative uncharacterized protein; n=3; ... 144 1e-32
UniRef50_O60674 Cluster: Tyrosine-protein kinase JAK2; n=48; Eut... 144 1e-32
UniRef50_UPI00015B629F Cluster: PREDICTED: similar to CG33531-PA... 143 2e-32
UniRef50_Q9BI25 Cluster: SHK1 protein; n=2; Dictyostelium discoi... 143 2e-32
UniRef50_A7SI92 Cluster: Predicted protein; n=2; Nematostella ve... 143 2e-32
UniRef50_P15056 Cluster: B-Raf proto-oncogene serine/threonine-p... 143 2e-32
UniRef50_Q10656-2 Cluster: Isoform b of Q10656 ; n=4; Caenorhabd... 142 3e-32
UniRef50_Q012D5 Cluster: Tyrosine kinase specific for activated ... 142 3e-32
UniRef50_Q16LR4 Cluster: Tyrosine protein kinase; n=5; Coelomata... 142 3e-32
UniRef50_Q10656 Cluster: Myoblast growth factor receptor egl-15 ... 142 3e-32
UniRef50_O02466 Cluster: Insulin-like peptide receptor precursor... 142 4e-32
UniRef50_Q95YM9 Cluster: Fibroblast growth factor receptor precu... 142 4e-32
UniRef50_Q8I7I5 Cluster: Roller: helically twisted, animals roll... 141 7e-32
UniRef50_Q8UVR8 Cluster: Macrophage colony-stimulating factor 1 ... 141 7e-32
UniRef50_O01325 Cluster: Putative uncharacterized protein; n=2; ... 141 9e-32
UniRef50_Q19238 Cluster: Putative tyrosine-protein kinase F09A5.... 141 9e-32
UniRef50_Q17IF1 Cluster: Receptor protein tyrosine kinase; n=1; ... 140 1e-31
UniRef50_P34925 Cluster: Tyrosine-protein kinase RYK precursor; ... 140 1e-31
UniRef50_UPI00015B4DC3 Cluster: PREDICTED: similar to receptor t... 140 2e-31
UniRef50_Q25199 Cluster: Tyrosine kinase receptor; n=7; Hydra|Re... 140 2e-31
UniRef50_P34265 Cluster: Probable tyrosine-protein kinase kin-31... 140 2e-31
UniRef50_Q4RXV8 Cluster: Chromosome 11 SCAF14979, whole genome s... 140 2e-31
UniRef50_Q4L0H7 Cluster: Insulin receptor tyrosine kinase; n=2; ... 140 2e-31
UniRef50_Q4RH14 Cluster: Chromosome undetermined SCAF15074, whol... 139 3e-31
UniRef50_Q640T5 Cluster: Tyrosine-protein kinase receptor; n=2; ... 139 4e-31
UniRef50_O02064 Cluster: Putative uncharacterized protein; n=1; ... 139 4e-31
UniRef50_P09619 Cluster: Beta-type platelet-derived growth facto... 139 4e-31
UniRef50_UPI0000D8BE91 Cluster: UPI0000D8BE91 related cluster; n... 138 5e-31
UniRef50_Q7ZTR8 Cluster: Serine/Threonine protein kinase RAF1; n... 138 5e-31
UniRef50_Q7T6Y2 Cluster: Putative serine/threonine-protein kinas... 138 5e-31
UniRef50_Q1HTP1 Cluster: Tyrosine-protein kinase receptor; n=1; ... 138 7e-31
UniRef50_Q5YKK5 Cluster: CTR1-like protein kinase; n=12; core eu... 138 7e-31
UniRef50_Q18865 Cluster: Putative uncharacterized protein; n=5; ... 138 7e-31
UniRef50_O76809 Cluster: Receptor tyrosine kinase HTK30; n=1; Hy... 138 7e-31
UniRef50_Q8T0W6 Cluster: Putative insulin receptor precursor; n=... 138 9e-31
UniRef50_UPI0000519EF1 Cluster: PREDICTED: similar to CG31640-PA... 137 1e-30
UniRef50_P35968 Cluster: Vascular endothelial growth factor rece... 137 1e-30
UniRef50_P18475 Cluster: Tyrosine-protein kinase receptor torso ... 137 1e-30
UniRef50_Q8JFR5 Cluster: Mast/stem cell growth factor receptor p... 137 1e-30
UniRef50_UPI0000E470E3 Cluster: PREDICTED: similar to Fer, parti... 137 2e-30
UniRef50_Q8IQ00 Cluster: CG3277-PB, isoform B; n=3; Sophophora|R... 137 2e-30
UniRef50_Q01JS4 Cluster: OSIGBa0152L12.10 protein; n=4; Oryza sa... 136 2e-30
UniRef50_Q8AXB3 Cluster: Vascular endothelial growth factor rece... 136 2e-30
UniRef50_Q4SJQ3 Cluster: Tyrosine-protein kinase receptor; n=1; ... 136 3e-30
UniRef50_Q9XW34 Cluster: Putative uncharacterized protein; n=3; ... 136 3e-30
UniRef50_Q9U8U8 Cluster: VEGFR-like; n=1; Branchiostoma belcheri... 136 3e-30
UniRef50_O17755 Cluster: Putative uncharacterized protein; n=3; ... 136 3e-30
UniRef50_Q9M085 Cluster: Protein kinase-like protein; n=22; Magn... 135 5e-30
UniRef50_Q54Y55 Cluster: SH2 domain-containing protein; n=1; Dic... 135 5e-30
UniRef50_A2FI59 Cluster: TKL family protein kinase; n=1; Trichom... 135 5e-30
UniRef50_Q7T6X2 Cluster: Putative serine/threonine-protein kinas... 135 5e-30
UniRef50_Q9C833 Cluster: Protein kinase, putative; 42705-46677; ... 135 6e-30
UniRef50_Q19726 Cluster: Putative uncharacterized protein kin-14... 135 6e-30
UniRef50_O01798 Cluster: Defective spermatogenesis protein 8; n=... 135 6e-30
UniRef50_P17948 Cluster: Vascular endothelial growth factor rece... 135 6e-30
UniRef50_UPI0000E49AD1 Cluster: PREDICTED: similar to mixed line... 134 8e-30
UniRef50_Q259N0 Cluster: H0723C07.13 protein; n=4; Oryza sativa|... 134 8e-30
UniRef50_P07333 Cluster: Macrophage colony-stimulating factor 1 ... 134 8e-30
UniRef50_Q9GZG1 Cluster: Putative uncharacterized protein; n=6; ... 134 1e-29
UniRef50_Q54TM7 Cluster: Leucine-rich repeat-containing protein;... 134 1e-29
UniRef50_Q17833 Cluster: Putative uncharacterized protein old-1;... 134 1e-29
UniRef50_P16234 Cluster: Alpha-type platelet-derived growth fact... 134 1e-29
UniRef50_UPI0000E468FC Cluster: PREDICTED: similar to KLG; n=3; ... 134 1e-29
UniRef50_Q61CN6 Cluster: Putative uncharacterized protein CBG128... 134 1e-29
UniRef50_P10721 Cluster: Mast/stem cell growth factor receptor p... 133 2e-29
UniRef50_Q4H3A3 Cluster: Janus kinase; n=1; Ciona intestinalis|R... 133 2e-29
UniRef50_Q15516 Cluster: Tyrosine kinase; n=1; Homo sapiens|Rep:... 133 2e-29
UniRef50_UPI0000E468CF Cluster: PREDICTED: similar to Ephrin typ... 132 3e-29
UniRef50_Q5FBD1 Cluster: Serine/threonine protein kinase ARAF; n... 132 4e-29
UniRef50_Q9Y1Z4 Cluster: Protein tyrosine kinase 37; n=1; Hydra ... 132 4e-29
UniRef50_P42159 Cluster: Class II receptor tyrosine kinase; n=5;... 132 4e-29
UniRef50_Q7Q0U2 Cluster: ENSANGP00000012311; n=1; Anopheles gamb... 132 6e-29
UniRef50_A7R2R7 Cluster: Chromosome chr4 scaffold_443, whole gen... 131 7e-29
UniRef50_A4S2A1 Cluster: Predicted protein; n=1; Ostreococcus lu... 131 7e-29
UniRef50_Q9I8N6 Cluster: Macrophage colony-stimulating factor 1 ... 131 7e-29
UniRef50_UPI00006A0D3B Cluster: Tyrosine protein-kinase STYK1 (E... 131 1e-28
UniRef50_P34891 Cluster: Receptor-like tyrosine-protein kinase k... 131 1e-28
UniRef50_Q05609 Cluster: Serine/threonine-protein kinase CTR1; n... 131 1e-28
UniRef50_Q6ER39 Cluster: CTR1-like kinase kinase kinase-like; n=... 130 1e-28
UniRef50_Q0DDD4 Cluster: Os06g0232100 protein; n=5; Oryza sativa... 130 1e-28
UniRef50_A2YAZ9 Cluster: Putative uncharacterized protein; n=1; ... 130 1e-28
UniRef50_P91360 Cluster: Putative uncharacterized protein; n=1; ... 130 1e-28
UniRef50_UPI0000DB72A0 Cluster: PREDICTED: similar to R151.4a; n... 130 2e-28
UniRef50_Q613B1 Cluster: Putative uncharacterized protein CBG164... 130 2e-28
UniRef50_P35916 Cluster: Vascular endothelial growth factor rece... 130 2e-28
UniRef50_UPI00015B54DC Cluster: PREDICTED: similar to vascular e... 129 3e-28
UniRef50_UPI0000F1FDC5 Cluster: PREDICTED: similar to ENSANGP000... 128 5e-28
UniRef50_Q9U8U9 Cluster: PDGFR-like; n=1; Eptatretus burgeri|Rep... 128 5e-28
UniRef50_Q4RNL0 Cluster: Chromosome 21 SCAF15012, whole genome s... 128 5e-28
UniRef50_Q4H2M8 Cluster: Tyrosine-protein kinase receptor; n=1; ... 128 5e-28
UniRef50_A2E1W1 Cluster: TKL family protein kinase; n=1; Trichom... 128 5e-28
UniRef50_P79749 Cluster: Beta-type platelet-derived growth facto... 128 5e-28
UniRef50_UPI00015B4F3C Cluster: PREDICTED: similar to CG2845-PA;... 128 7e-28
UniRef50_UPI0000D576E5 Cluster: PREDICTED: similar to CG33531-PA... 128 7e-28
UniRef50_Q9LMF8 Cluster: F16A14.22; n=9; Magnoliophyta|Rep: F16A... 128 7e-28
UniRef50_O43283 Cluster: Mitogen-activated protein kinase kinase... 128 7e-28
UniRef50_A0C299 Cluster: Chromosome undetermined scaffold_144, w... 128 9e-28
UniRef50_Q5GIT4 Cluster: Vascular endothelial growth factor rece... 128 9e-28
UniRef50_Q4JDD5 Cluster: Tyrosine-protein kinase receptor; n=5; ... 127 1e-27
UniRef50_Q1HTP2 Cluster: Tyrosine-protein kinase receptor; n=4; ... 127 1e-27
UniRef50_Q5XTZ4 Cluster: Salt-inducible protein kinase; n=2; Poa... 127 1e-27
UniRef50_Q27324 Cluster: Tyrosine-protein kinase Drl precursor; ... 127 1e-27
UniRef50_Q4S5N1 Cluster: Chromosome 9 SCAF14729, whole genome sh... 127 2e-27
UniRef50_Q1SMZ9 Cluster: Protein kinase; n=3; Viridiplantae|Rep:... 127 2e-27
UniRef50_Q12852 Cluster: Mitogen-activated protein kinase kinase... 127 2e-27
UniRef50_UPI00015B4B9F Cluster: PREDICTED: similar to prenylcyst... 126 2e-27
UniRef50_Q94AB2 Cluster: AT3g58640/F14P22_230; n=13; Magnoliophy... 126 2e-27
UniRef50_Q9VLQ8 Cluster: CG8222-PA, isoform A; n=8; Sophophora|R... 126 2e-27
UniRef50_Q8T4M0 Cluster: VEGFR-A splice form A; n=4; Diptera|Rep... 126 2e-27
UniRef50_Q55A09 Cluster: Kelch repeat-containing protein; n=4; D... 126 2e-27
UniRef50_Q9FKL3 Cluster: Similarity to protein kinase; n=1; Arab... 126 4e-27
UniRef50_A7PH50 Cluster: Chromosome chr17 scaffold_16, whole gen... 126 4e-27
UniRef50_A7RWY4 Cluster: Predicted protein; n=1; Nematostella ve... 126 4e-27
UniRef50_Q2MHE4 Cluster: Serine/threonine-protein kinase HT1; n=... 126 4e-27
UniRef50_UPI0000F1F986 Cluster: PREDICTED: similar to mixed line... 125 5e-27
UniRef50_UPI0000DB7A0A Cluster: PREDICTED: similar to FMS-like t... 125 5e-27
UniRef50_UPI000049A16F Cluster: protein kinase; n=1; Entamoeba h... 125 5e-27
UniRef50_Q0DE32 Cluster: Os06g0181200 protein; n=5; Oryza sativa... 125 7e-27
UniRef50_A7Q6K4 Cluster: Chromosome chr11 scaffold_56, whole gen... 125 7e-27
UniRef50_Q54XQ2 Cluster: RGS domain-containing protein; n=2; Dic... 125 7e-27
UniRef50_Q54H46 Cluster: Protein kinase, TKL group; n=1; Dictyos... 125 7e-27
UniRef50_Q23102 Cluster: Putative uncharacterized protein; n=1; ... 125 7e-27
UniRef50_P34892 Cluster: Receptor-like tyrosine-protein kinase k... 125 7e-27
UniRef50_UPI0000D560EA Cluster: PREDICTED: similar to CG31127-PA... 124 9e-27
>UniRef50_Q6VU50 Cluster: Eph receptor; n=3; Endopterygota|Rep: Eph
receptor - Manduca sexta (Tobacco hawkmoth) (Tobacco
hornworm)
Length = 1011
Score = 1690 bits (4189), Expect = 0.0
Identities = 779/904 (86%), Positives = 826/904 (91%), Gaps = 3/904 (0%)
Query: 44 GNALSCKETFSLLYYEFDVATREQPPWEPESYKLVGRIAAGEGRFNTNSEVDINTEVKSI 103
GNALSCKETFSLLYYEFDVATREQPPWEPESYKLVGRIAAGEGRFNTNSEVDINTEVKSI
Sbjct: 109 GNALSCKETFSLLYYEFDVATREQPPWEPESYKLVGRIAAGEGRFNTNSEVDINTEVKSI 168
Query: 104 AVTKKGVYFAFRDQGACISILAVKVYYITCPDVNINFARFPATPTGREVTVIEQANGTCV 163
AVTK+GVYFAFRDQGACISILAVKVYYITCP+V INFARFPATPTGREVTVIEQANGTCV
Sbjct: 169 AVTKRGVYFAFRDQGACISILAVKVYYITCPEVTINFARFPATPTGREVTVIEQANGTCV 228
Query: 164 ANAEVAPGEKAPVYLCKGDGKWTLPSGSCKCRAGFEPDHNNQICTECAPGKFKSHTGDEH 223
NAE+APGE PVYLCKGDGKWTLPSGSCKCRAGFEPDHNNQ CTEC PGKFK+HTGD+H
Sbjct: 229 ENAEIAPGEAPPVYLCKGDGKWTLPSGSCKCRAGFEPDHNNQACTECPPGKFKAHTGDDH 288
Query: 224 CIPCPDHSESTIYAAAECKCTPKYYRAKKDPKTIPCTQPPSAPDNLTVTFADQFSISLTW 283
CIPCPDHS+ST AA+EC+C PKYYRAKKDPK IPCTQPPSAPDNLTVTFADQFSISL W
Sbjct: 289 CIPCPDHSQSTAIAASECRCAPKYYRAKKDPKNIPCTQPPSAPDNLTVTFADQFSISLAW 348
Query: 284 QPPHNTGGRSDITYKISCANCGPTVEFRPGETGLNSTRVTISGLDPVTEYKFQVYAENGV 343
+PPHNTGGR+D+TY++ C NCGP+VE+RP TGLN+TRVT+ GLDPVTEYKFQV+AENGV
Sbjct: 349 RPPHNTGGRNDVTYRVYCLNCGPSVEYRPAATGLNNTRVTVMGLDPVTEYKFQVFAENGV 408
Query: 344 SELSPDPANHIEITAVTEAXXXXXXXKLRILNTESDRLTIAWNPPQVDLTDPDDTIESYE 403
+E + DP +++ITA+TEA KLR+LN E D++++AWNPP VDLTDPDDTIESYE
Sbjct: 409 TEFTSDPPKYVDITAITEASVVSVVTKLRVLNVEVDKISLAWNPPPVDLTDPDDTIESYE 468
Query: 404 VKCFPKDSQDKNTNTTLRITKDPQVTITGLRKDTEYGIRVRAKMKRGWGEFSGIVYARTN 463
VKCFPKD+ +KN NTTL+ITK+P I GL+KDTEYGIRVRAKMKRGWGEFS IVYART
Sbjct: 469 VKCFPKDNLEKNANTTLKITKEPHTIIMGLKKDTEYGIRVRAKMKRGWGEFSSIVYARTG 528
Query: 464 SVTETSFI-DEEGAQXXXXXXXXXXXXXXXXXXXXXXXXFLRSRADDECDKKQPSDCNAL 522
++ ET+++ +EEGAQ FLRSR +DECDKKQP DCNAL
Sbjct: 529 NLLETTYVNEEEGAQVRLVAGVMVAVVVLSVVAIIATVLFLRSRTEDECDKKQPGDCNAL 588
Query: 523 NYRNGEVYTGPDRPAKTSSNATTPLFAGTGSRTYIDPHTYEDPNQAVREFAREIDASCIT 582
NYRNGEVY+GP+RPAKTSSNATTPLFAGTGSRTYIDPHTYEDPNQAVREFAREIDASCIT
Sbjct: 589 NYRNGEVYSGPERPAKTSSNATTPLFAGTGSRTYIDPHTYEDPNQAVREFAREIDASCIT 648
Query: 583 IEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEASIMGQFEHP 642
IEAIIGGGEFGDVCRGKLKL ASCG EIDVAIKTLKPGSTERARRDFLAEASIMGQFEHP
Sbjct: 649 IEAIIGGGEFGDVCRGKLKL-ASCGQEIDVAIKTLKPGSTERARRDFLAEASIMGQFEHP 707
Query: 643 NVIFLQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFRVLQLVGMLRGIATGMQYLSEM 702
NVIFLQGVVTKCNPIMIITEFMENGSLDTFLRANDGKF VLQLVGMLRGIATGMQYLSEM
Sbjct: 708 NVIFLQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFMVLQLVGMLRGIATGMQYLSEM 767
Query: 703 NYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGGKIPVRWTAPEAIAFRK 762
NYIHRDLAARNVLVNS LVCKIADFGLSREIESTADGAYTTRGGKIPVRWTAPEAIAFRK
Sbjct: 768 NYIHRDLAARNVLVNSHLVCKIADFGLSREIESTADGAYTTRGGKIPVRWTAPEAIAFRK 827
Query: 763 FTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEAVYQLMLDC 822
FTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEAVYQLMLDC
Sbjct: 828 FTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEAVYQLMLDC 887
Query: 823 WQKERTHRPTFSSIVKTLDKLIRCPDTLRKIAQNRS-ADPLAGDTPDLIQFTSVEEWLEC 881
WQKERTHRPTF+SIVKTLDKLI PDTLRK AQNRS ADPLAGDTPDLIQF SVEEWLEC
Sbjct: 888 WQKERTHRPTFASIVKTLDKLIGYPDTLRKKAQNRSGADPLAGDTPDLIQFASVEEWLEC 947
Query: 882 IKMSRYIEKFRAAGISDMDAVVDLTVHQLASLGVTLVGHQKKIMNSVQSMRAQIRGSGPY 941
IKMSRY+EKFRA G++DMDAVVDLTV QLASLGVTLVGHQKKIMNSVQSMRA IRGSGPY
Sbjct: 948 IKMSRYVEKFRAGGVTDMDAVVDLTVLQLASLGVTLVGHQKKIMNSVQSMRAHIRGSGPY 1007
Query: 942 GFLV 945
GFLV
Sbjct: 1008 GFLV 1011
>UniRef50_Q5D184 Cluster: Ephrin receptor; n=2; Apocrita|Rep: Ephrin
receptor - Apis mellifera (Honeybee)
Length = 996
Score = 1253 bits (3103), Expect = 0.0
Identities = 586/902 (64%), Positives = 688/902 (76%), Gaps = 7/902 (0%)
Query: 44 GNALSCKETFSLLYYEFDVATREQPPWEPESYKLVGRIAAGEGRFNTNSEVDINTEVKSI 103
GNALSCKETFSLLYYEFDVAT+E PPWE +SYKL+GRIAAGEGRFNTN+EV INTEVKSI
Sbjct: 102 GNALSCKETFSLLYYEFDVATKEPPPWETDSYKLIGRIAAGEGRFNTNTEVVINTEVKSI 161
Query: 104 AVTKKGVYFAFRDQGACISILAVKVYYITCPDVNINFARFPATPTGREVTVIEQANGTCV 163
VTKKGVYFAFRDQGACISILA+KVYYI+CP++++NFA FPATPTGREV +IEQ GTCV
Sbjct: 162 PVTKKGVYFAFRDQGACISILAIKVYYISCPEISVNFAHFPATPTGREVALIEQTIGTCV 221
Query: 164 ANAEVAPGEKAPVYLCKGDGKWTLPSGSCKCRAGFEPDHNNQICTECAPGKFKSHTGDEH 223
ANA V + P +LCKGDGKW LPSG C C+ G++ D Q CTEC GKFK G
Sbjct: 222 ANAVVI---EQPTFLCKGDGKWYLPSGGCHCKPGYQADVEKQECTECPIGKFKHEAGSHS 278
Query: 224 CIPCPDHSESTIYAAAECKCTPKYYRAKKDPKTIPCTQPPSAPDNLTVTFADQFSISLTW 283
C CP HS+S+ Y EC+C P Y+RA+KDPK +PCTQPPSAP NLTV F DQ ++ L+W
Sbjct: 279 CEACPAHSKSSDYGFTECRCDPGYFRAEKDPKKMPCTQPPSAPQNLTVNFVDQSTVFLSW 338
Query: 284 QPPHNTGGRSDITYKISCANCGPTVEFRPGETGLNSTRVTISGLDPVTEYKFQVYAENGV 343
PH GGR+D TY++ C C V++ P N T++TI+GL+ VT Y+FQV+AENGV
Sbjct: 339 NAPHMLGGRTDTTYRVVCDACSMGVKYIPNTEVFNDTKITITGLNAVTTYRFQVFAENGV 398
Query: 344 SELSPDPANHIEITAVTEAXXXXXXXKLRILNTESDRLTIAWNPPQVDLTDPDDTIESYE 403
S L+ + +++IT T+A +RI + +S L+I+W+ P ++ D +E YE
Sbjct: 399 SALA-GKSEYVDITVTTDASVPSLVSNVRITSVKSSELSISWDAPITEIGGDSDLVERYE 457
Query: 404 VKCFPKDSQDKNTNTTLRITKDPQVTITGLRKDTEYGIRVRAKMKRGWGEFSGIVYARTN 463
V+C+P+ D TN T+ T + T GL+ T+Y I+VRAK RGWGE++ +VY +T
Sbjct: 458 VRCYPR--YDDATNATVIQTSELSATFKGLKPSTDYAIQVRAKTTRGWGEYTPVVYKKTP 515
Query: 464 SVTETSFIDEEGAQXXXXXXXXXXXXXXXXXXXXXXXXFLRSRADDECDKKQPSDCNALN 523
++ E+ + RA DEC+KKQPSDC+ L
Sbjct: 516 HAMGLDYVGEDDNMQVRIIAGAIVAVVVLLVIIIIMTVLILRRASDECNKKQPSDCDTLE 575
Query: 524 YRNGEVYTGPDRPAKTSSNATTPLFAGTGSRTYIDPHTYEDPNQAVREFAREIDASCITI 583
YRNGEV T PA + A+ G G+R+Y+DPHTYEDPNQAVREFAREIDA ITI
Sbjct: 576 YRNGEVTTPLFTPAVGVAAASAGGAGGGGARSYVDPHTYEDPNQAVREFAREIDAGYITI 635
Query: 584 EAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEASIMGQFEHPN 643
EAIIGGGEFGDVCRGKLKLP EIDVAIKTLKPGS ++AR DFL EASIMGQFEHPN
Sbjct: 636 EAIIGGGEFGDVCRGKLKLPPDGRTEIDVAIKTLKPGSADKARNDFLTEASIMGQFEHPN 695
Query: 644 VIFLQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFRVLQLVGMLRGIATGMQYLSEMN 703
VIFLQGVVTK NP+MIITEFMENGSLDTFLRANDGKF+VLQLVGMLRGIA+GMQYL+EMN
Sbjct: 696 VIFLQGVVTKSNPVMIITEFMENGSLDTFLRANDGKFQVLQLVGMLRGIASGMQYLAEMN 755
Query: 704 YIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGGKIPVRWTAPEAIAFRKF 763
Y+HRDLAARNVLVN+ LVCKIADFGLSREIES +GAYTTRGGKIPVRWTAPEAIAFRKF
Sbjct: 756 YVHRDLAARNVLVNAALVCKIADFGLSREIESATEGAYTTRGGKIPVRWTAPEAIAFRKF 815
Query: 764 TSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEAVYQLMLDCW 823
TSASDVWSMGIVCWEVMS+GERPYWNWSNQDVIKSIEKGYRLPAPMDCPEA+YQLMLDCW
Sbjct: 816 TSASDVWSMGIVCWEVMSYGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEAIYQLMLDCW 875
Query: 824 QKERTHRPTFSSIVKTLDKLIRCPDTLRKIAQNRSADPLAGDTPDLIQFTSVEEWLECIK 883
QKERTHRPTF+++ +TLDKLIR PDTLRKIAQNR +PLA D DL Q TSV EWL IK
Sbjct: 876 QKERTHRPTFANLTQTLDKLIRSPDTLRKIAQNRGTNPLAPDAVDLTQLTSVSEWLASIK 935
Query: 884 MSRYIEKFRAAGISDMDAVVDLTVHQLASLGVTLVGHQKKIMNSVQSMRAQIRGSGPYGF 943
MSRY E F +G++ ++A +TV +L +LGVTLVGHQKKIMNSV ++RAQ+ + GF
Sbjct: 936 MSRYAESFERSGVTTLEAAARVTVQELTALGVTLVGHQKKIMNSVTALRAQMSATS-QGF 994
Query: 944 LV 945
LV
Sbjct: 995 LV 996
>UniRef50_Q9V4E5 Cluster: CG1511-PC, isoform C; n=12; Diptera|Rep:
CG1511-PC, isoform C - Drosophila melanogaster (Fruit
fly)
Length = 1096
Score = 992 bits (2455), Expect = 0.0
Identities = 511/936 (54%), Positives = 625/936 (66%), Gaps = 63/936 (6%)
Query: 44 GNALSCKETFSLLYYEFDVATREQPPWEPESYKLVGRIAAGEGRFNTNSEVDINTEVKSI 103
GNALSCKETFSLL+YEFD ATRE PPW+ +SY+L+ RIAAGEGRFN NS+VDINTEVKSI
Sbjct: 172 GNALSCKETFSLLFYEFDAATREPPPWQTDSYRLIARIAAGEGRFNQNSDVDINTEVKSI 231
Query: 104 AVTKKGVYFAFRDQGACISILAVKVYYITCPDVNINFARFPATPTGREVTVIEQANGTCV 163
AV KKGVYFAFRDQGACIS+LAVKVYYITCP V NFA F TPTGRE+T+IE+ NGTCV
Sbjct: 232 AVNKKGVYFAFRDQGACISVLAVKVYYITCPAVTENFAHFNETPTGREITIIEKQNGTCV 291
Query: 164 ANAEVAPGEKAPVYLCKGDGKWTLPSGSCKCRAGFEPDHNNQICTECAPGKFKSHTGDEH 223
NAE P E P YLCKGDGKWT+ +G C+C+AG+EP++ N+ CTEC G FKS +
Sbjct: 292 DNAE--PYE-TPTYLCKGDGKWTILTGGCRCKAGYEPNYTNKTCTECPLGTFKSPEVTK- 347
Query: 224 CIPCPDHSESTIYAAAECKCTPKYYRAKKDPKTIPCTQPPSAPDNLTVTFADQFSISLTW 283
C PCP +S ++ + CKC +YR D + +PC PP+AP NLT+ F DQ S ++W
Sbjct: 348 CTPCPPNSNASKTGSPFCKCASGFYRHPNDGRHMPCYSPPAAPTNLTLLFVDQTSAIISW 407
Query: 284 QPP-------HNTGGR---SDITYKISCANCGPTVEFRPG-----ETGLNSTRV------ 322
P T + SDI YKI C C P V + P ET + T +
Sbjct: 408 SAPAKNESFSSETNSKIYHSDIVYKIKCNICSPNVVYNPSTDTFNETKITLTNLEPVTTY 467
Query: 323 -----TISGLDPVTEYKFQ------------VYAENGVSELSPD----PANHIEITAVTE 361
I+ + + E+K V++ + + D EI TE
Sbjct: 468 TVQIHAINSVSHINEFKRHSNESSLVAVSDIVFSNTSLLNIPLDLNEVKTGQAEIVFTTE 527
Query: 362 AXXXXXXXKLRILNTESDRLTIAWNPPQVDLTDPDDTIESYEVKCFPKDSQDKNTNTTLR 421
+ LRIL + + W+ P D +E YEV+ FPK D + L
Sbjct: 528 SVLLSTVFNLRILAITNKDADLEWDKP----VQSDFPLEFYEVRWFPKVELDAINKSALN 583
Query: 422 ITKDPQVTITGLRKDTEYGIRVRAKMKRGWGEFSGIVYARTNSVTETSFIDEEGAQXXXX 481
TK+ + I GL ++TEYG +VR K G+G +S ++YA+T + + ++ Q
Sbjct: 584 -TKETKAHIVGLLENTEYGFQVRCKTNNGFGSYSNMIYAQT--LQSVGSVYDDSVQIRFI 640
Query: 482 XXXXXXXXXXXXXXXXXXXXFLRSRADDECDKKQPSDCNA-LNYRNGEVYTGPDRPA--K 538
F+RS+ D+ DKK + L+Y + EV + P K
Sbjct: 641 AGAIVTGVLFLVIFIIATVYFMRSKHQDDLDKKSTNHLPLPLDYASNEVNSMDTTPIVKK 700
Query: 539 TSSNATTPLFAGTGSRTYIDPHTYEDPNQAVREFAREIDASCITIEAIIGGGEFGDVCRG 598
N TTPLF SR+Y+DPHTYEDPNQA+REFAREIDA+ ITIEAIIGGGEFGDVCRG
Sbjct: 701 LHLNVTTPLFGN--SRSYVDPHTYEDPNQAIREFAREIDANYITIEAIIGGGEFGDVCRG 758
Query: 599 KLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEASIMGQFEHPNVIFLQGVVTKCNPIM 658
+LK+P + +IDVAIKTLKPGS+E+AR DFL EASIMGQF+HPNVI+LQGVVT+ NP+M
Sbjct: 759 RLKIPPNFVQDIDVAIKTLKPGSSEKARCDFLTEASIMGQFDHPNVIYLQGVVTRSNPVM 818
Query: 659 IITEFMENGSLDTFLRANDGKFRVLQLVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNS 718
IITE+MENGSLDTFLR NDGKF+ LQL+ MLRGIA+GM YLS+MNY+HRDLAARNVLVN+
Sbjct: 819 IITEYMENGSLDTFLRVNDGKFQTLQLIVMLRGIASGMSYLSDMNYVHRDLAARNVLVNA 878
Query: 719 QLVCKIADFGLSREIESTADGAYTTRGGKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWE 778
QL+CKIADFGLSREIE+ +D AYTTRGGKIPVRWTAPEAIAFRKFTSASDVWS G+V WE
Sbjct: 879 QLICKIADFGLSREIENASD-AYTTRGGKIPVRWTAPEAIAFRKFTSASDVWSYGVVLWE 937
Query: 779 VMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVK 838
VMS+GERPYWNWSNQDVIKSIEKGYRLPAPMDCPEA+YQLMLDCWQK+RTHRPTF+SIV
Sbjct: 938 VMSYGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEALYQLMLDCWQKQRTHRPTFASIVS 997
Query: 839 TLDKLIRCPDTLRKIAQNRSADP---LAGDTPDLIQFTSVEEWLECIKMSRYIEKFRAAG 895
TLD L R P +L + +D L G I F S + WLE IKMSRY F+ A
Sbjct: 998 TLDNLARQPQSLLTTRPSPESDGNHILDGQRGQNI-FISTDLWLEHIKMSRYCHHFKEAN 1056
Query: 896 ISDMDAVVDLTVHQLASLGVTLVGHQKKIMNSVQSM 931
+ + + LT QL+ +G+TLVGHQKKI++ + +
Sbjct: 1057 LINAQQISRLTAQQLSDMGITLVGHQKKILHQARQL 1092
>UniRef50_P54756 Cluster: Ephrin type-A receptor 5 precursor; n=103;
Euteleostomi|Rep: Ephrin type-A receptor 5 precursor -
Homo sapiens (Human)
Length = 1037
Score = 792 bits (1959), Expect = 0.0
Identities = 421/912 (46%), Positives = 552/912 (60%), Gaps = 43/912 (4%)
Query: 44 GNALSCKETFSLLYYEFDVATREQPPWEPESYKLVGRIAAGEG--RFNTNSEV-DINTEV 100
G +CKETF++ Y+E D + Y + IAA E + V +NTEV
Sbjct: 142 GGLGTCKETFNMYYFESDDQNGRNI--KENQYIKIDTIAADESFTELDLGDRVMKLNTEV 199
Query: 101 KSIA-VTKKGVYFAFRDQGACISILAVKVYYITCPDVNINFARFPATPTGREVTVIEQAN 159
+ + ++KKG Y AF+D GACI++++V+VYY CP V + A FP T TG + + + + +
Sbjct: 200 RDVGPLSKKGFYLAFQDVGACIALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVS 259
Query: 160 GTCVANAEVAPGEKAPVYLCKGDGKWTLPSGSCKCRAGFEPDHNNQICTECAPGKFKSHT 219
G+CV N V ++ P C +G+W +P G C C+AG+E N C C PG FK+
Sbjct: 260 GSCV-NHSVT--DEPPKMHCSAEGEWLVPIGKCMCKAGYE--EKNGTCQVCRPGFFKASP 314
Query: 220 GDEHCIPCPDHSESTIYAAAECKCTPKYYRAKKDPKTIPCTQPPSAPDNLTVTFADQFSI 279
+ C CP HS + A+ C C Y+R + DP T+ CT+PPSAP N ++ ++ S+
Sbjct: 315 HIQSCGKCPPHSYTHEEASTSCVCEKDYFRRESDPPTMACTRPPSAPRN-AISNVNETSV 373
Query: 280 SLTWQPPHNTGGRSDITYKISCANC----------GPTVEFRPGETGLNSTRVTISGLDP 329
L W PP +TGGR D++Y I+C C G V + P ++GL +T V + L
Sbjct: 374 FLEWIPPADTGGRKDVSYYIACKKCNSHAGVCEECGGHVRYLPRQSGLKNTSVMMVDLLA 433
Query: 330 VTEYKFQVYAENGVSELSPDPANHIEITAVTEAXXXXXXXKLRILNTESDRLTIAWNPPQ 389
T Y F++ A NGVS+LSP ++ + T ++ + ++++W P
Sbjct: 434 HTNYTFEIEAVNGVSDLSPGARQYVSVNVTTNQAAPSPVTNVKKGKIAKNSISLSWQEPD 493
Query: 390 VDLTDPDDTIESYEVKCFPKDSQDKNTNTTLRITKDPQVTITGLRKDTEYGIRVRAKMKR 449
P+ I YE+K F KD + T+ T+ +K+ +T GL+ + Y ++RA+
Sbjct: 494 ----RPNGIILEYEIKHFEKDQE---TSYTIIKSKETTITAEGLKPASVYVFQIRARTAA 546
Query: 450 GWGEFSGIVYARTNSVTETSFIDEEGAQXXXXXXXXXXXXXXXXXXXXXXXXFLR---SR 506
G+G FS T V S D+ R
Sbjct: 547 GYGVFSRRFEFETTPVFAASS-DQSQIPVIAVSVTVGVILLAVVIGVLLSGSCCECGCGR 605
Query: 507 ADDECDKKQPSDCNALNYRNGEVYTGPDRPAKTSSNATTPLFAGTGSRTYIDPHTYEDPN 566
A C P Y + P+ N L G RTYIDPHTYEDPN
Sbjct: 606 ASSLCAVAHPILIWRCGYSKAK--QDPEEEKMHFHNGHIKL---PGVRTYIDPHTYEDPN 660
Query: 567 QAVREFAREIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERAR 626
QAV EFA+EI+ASCITIE +IG GEFG+VC G+LKLP E+ VAIKTLK G TE+ R
Sbjct: 661 QAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGK--RELPVAIKTLKVGYTEKQR 718
Query: 627 RDFLAEASIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFRVLQLV 686
RDFL EASIMGQF+HPN+I L+GVVTK P+MI+TE+MENGSLDTFL+ NDG+F V+QLV
Sbjct: 719 RDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLV 778
Query: 687 GMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGG 746
GMLRGI+ GM+YLS+M Y+HRDLAARN+L+NS LVCK++DFGLSR +E + AYTTRGG
Sbjct: 779 GMLRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGG 838
Query: 747 KIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLP 806
KIP+RWTAPEAIAFRKFTSASDVWS GIV WEV+S+GERPYW +NQDVIK++E+GYRLP
Sbjct: 839 KIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLP 898
Query: 807 APMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLIRCPDTLRKI--AQNRSADPLAG 864
+PMDCP A+YQLMLDCWQKER RP F IV LDKLIR P +L+ + A R ++ LA
Sbjct: 899 SPMDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKLIRNPSSLKTLVNASCRVSNLLAE 958
Query: 865 DTP-DLIQFTSVEEWLECIKMSRYIEKFRAAGISDMDAVVDLTVHQLASLGVTLVGHQKK 923
+P + SV EWLE IKM RY E F G S MDAV +T+ L LGVTLVGHQKK
Sbjct: 959 HSPLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSMDAVAQVTLEDLRRLGVTLVGHQKK 1018
Query: 924 IMNSVQSMRAQI 935
IMNS+Q M+ Q+
Sbjct: 1019 IMNSLQEMKVQL 1030
>UniRef50_P29322 Cluster: Ephrin type-A receptor 8 precursor; n=22;
Euteleostomi|Rep: Ephrin type-A receptor 8 precursor -
Homo sapiens (Human)
Length = 1005
Score = 710 bits (1755), Expect = 0.0
Identities = 389/918 (42%), Positives = 527/918 (57%), Gaps = 58/918 (6%)
Query: 48 SCKETFSLLYYEFDVATREQPPWEPESYKL-VGRIAAGEGRFNTNSEV---DINTEVKSI 103
+CKETF+L Y E D R+ ES L + IAA E + V +NTEV+S+
Sbjct: 117 TCKETFNLYYLESD---RDLGASTQESQFLKIDTIAADESFTGADLGVRRLKLNTEVRSV 173
Query: 104 A-VTKKGVYFAFRDQGACISILAVKVYYITCPDVNINFARFPATPTGREVTVIEQANGTC 162
++K+G Y AF+D GAC++IL++++YY CP + N A F TG + + + + G C
Sbjct: 174 GPLSKRGFYLAFQDIGACLAILSLRIYYKKCPAMVRNLAAFSEAVTGADSSSLVEVRGQC 233
Query: 163 VANAEVAPGEKAPVYLCKGDGKWTLPSGSCKCRAGFEPDHNNQICTECAPGKFKSHTGDE 222
V ++E P C +G+W +P G C C AG+E C C G +KS GD+
Sbjct: 234 VRHSEE---RDTPKMYCSAEGEWLVPIGKCVCSAGYE--ERRDACVACELGFYKSAPGDQ 288
Query: 223 HCIPCPDHSESTIYAAAECKCTPKYYRAKKDPKTIPCTQPPSAPDNLTVTFADQFSISLT 282
C CP HS S AA C C YYRA DP + CT+PPSAP NL ++ + S++L
Sbjct: 289 LCARCPPHSHSAAPAAQACHCDLSYYRAALDPPSSACTRPPSAPVNL-ISSVNGTSVTLE 347
Query: 283 WQPPHNTGGRSDITYKISCANC----------GPTVEFRPGETGLNSTRVTISGLDPVTE 332
W PP + GGRSDITY C C G F P +T L + ++ L
Sbjct: 348 WAPPLDPGGRSDITYNAVCRRCPWALSRCEACGSGTRFVPQQTSLVQASLLVANLLAHMN 407
Query: 333 YKFQVYAENGVSELSPDPANHIEITAVTEAXXXXXXXKLRILNTESDRLTIAWNPPQVDL 392
Y F + A NGVS+LSP+P + T +R +++ W P+
Sbjct: 408 YSFWIEAVNGVSDLSPEPRRAAVVNITTNQAAPSQVVVIRQERAGQTSVSLLWQEPE--- 464
Query: 393 TDPDDTIESYEVKCFPKDSQDKNTNTTLRITKDPQVTITGLRKDTEYGIRVRAKMKRGWG 452
P+ I YE+K + KD + ++ +T +T + T++GL+ T Y +VRA+ G G
Sbjct: 465 -QPNGIILEYEIKYYEKDKEMQSYSTLKAVTT--RATVSGLKPGTRYVFQVRARTSAGCG 521
Query: 453 EFSGIVYARTNSVTETSFIDEEGAQXXXXXXXXXXXXXXXXXXXXXXXXFLRSRADDECD 512
FS + T + + + R
Sbjct: 522 RFSQAMEVETG---------KPRPRYDTRTIVWICLTLITGLVVLLLLLICKKRHCGYSK 572
Query: 513 KKQPSDCNALNYRNGEVYTGPDRPAK-TSSNATTPLFAGTGSRTYIDPHTYEDPNQAVRE 571
Q SD ++Y+NG+ P P F Y +PHTYE+P +A R
Sbjct: 573 AFQDSDEEKMHYQNGQAPPPVFLPLHHPPGKLPEPQF-------YAEPHTYEEPGRAGRS 625
Query: 572 FAREIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLA 631
F REI+AS I IE IIG G+ G+VC G+L++P ++ VAIK LK G TER RRDFL+
Sbjct: 626 FTREIEASRIHIEKIIGSGDSGEVCYGRLRVPGQ--RDVPVAIKALKAGYTERQRRDFLS 683
Query: 632 EASIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFRVLQLVGMLRG 691
EASIMGQF+HPN+I L+GVVT+ MI+TE+MENGSLDTFLR +DG+F ++QLVGMLRG
Sbjct: 684 EASIMGQFDHPNIIRLEGVVTRGRLAMIVTEYMENGSLDTFLRTHDGQFTIMQLVGMLRG 743
Query: 692 IATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGGKIPVR 751
+ GM+YLS++ Y+HRDLAARNVLV+S LVCK++DFGLSR +E D AYTT GGKIP+R
Sbjct: 744 VGAGMRYLSDLGYVHRDLAARNVLVDSNLVCKVSDFGLSRVLEDDPDAAYTTTGGKIPIR 803
Query: 752 WTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDC 811
WTAPEAIAFR F+SASDVWS G+V WEV+++GERPYWN +N+DVI S+E+GYRLPAPM C
Sbjct: 804 WTAPEAIAFRTFSSASDVWSFGVVMWEVLAYGERPYWNMTNRDVISSVEEGYRLPAPMGC 863
Query: 812 PEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLIRCPDTLRKIAQNRSADPLA--GDTPDL 869
P A++QLMLDCW K+R RP FS IV LD LIR P++LR A P A DL
Sbjct: 864 PHALHQLMLDCWHKDRAQRPRFSQIVSVLDALIRSPESLRATATVSRCPPPAFVRSCFDL 923
Query: 870 IQFT------SVEEWLECIKMSRYIEKFRAAGISDMDAVVDLTVHQLASLGVTLVGHQKK 923
+ +V +WL+ I+M RY + F A G S + V+ + + +LG+TL+GHQKK
Sbjct: 924 RGGSGGGGGLTVGDWLDSIRMGRYRDHFAAGGYSSLGMVLRMNAQDVRALGITLMGHQKK 983
Query: 924 IMNSVQSMRAQIRGS-GP 940
I+ S+Q+MRAQ+ + GP
Sbjct: 984 ILGSIQTMRAQLTSTQGP 1001
>UniRef50_P29317 Cluster: Ephrin type-A receptor 2 precursor; n=32;
Euteleostomi|Rep: Ephrin type-A receptor 2 precursor -
Homo sapiens (Human)
Length = 976
Score = 682 bits (1686), Expect = 0.0
Identities = 382/915 (41%), Positives = 522/915 (57%), Gaps = 70/915 (7%)
Query: 44 GNALSCKETFSLLYYEFDVATREQPPWEPESYKLVGRIAAGEGRFNTNSE---VDINTEV 100
G A SCKETF+L Y E D+ ++ + + IA E +++ E V +N E
Sbjct: 110 GGASSCKETFNLYYAESDLDYGTN--FQKRLFTKIDTIAPDEITVSSDFEARHVKLNVEE 167
Query: 101 KSIA-VTKKGVYFAFRDQGACISILAVKVYYITCPDVNINFARFPATPTGREVTVIEQAN 159
+S+ +T+KG Y AF+D GAC+++L+V+VYY CP++ A FP T G + +
Sbjct: 168 RSVGPLTRKGFYLAFQDIGACVALLSVRVYYKKCPELLQGLAHFPETIAGSDAPSLATVA 227
Query: 160 GTCVANAEVAPGEKAPVYLCKGDGKWTLPSGSCKCRAGFEPDHNNQICTECAPGKFKSHT 219
GTCV +A V PG + P C DG+W +P G C C+AG+E + C C+PG FK
Sbjct: 228 GTCVDHAVVPPGGEEPRMHCAVDGEWLVPIGQCLCQAGYEKVED--ACQACSPGFFKFEA 285
Query: 220 GDEHCIPCPDHSESTIYAAAECKCTPKYYRAKKDPKTIPCTQPPSAPDNLTVTFADQFSI 279
+ C+ CP+H+ + A C+C ++RA +DP ++PCT+PPSAP LT +
Sbjct: 286 SESPCLECPEHTLPSPEGATSCECEEGFFRAPQDPASMPCTRPPSAPHYLTAVGMGA-KV 344
Query: 280 SLTWQPPHNTGGRSDITYKISCANCGP----------TVEFRPGETGLNSTRVTISGLDP 329
L W PP ++GGR DI Y ++C C P +V + GL T VT+S L+P
Sbjct: 345 ELRWTPPQDSGGREDIVYSVTCEQCWPESGECGPCEASVRYSEPPHGLTRTSVTVSDLEP 404
Query: 330 VTEYKFQVYAENGVSELSPDPANHIEITAVTEAXXXXXXXKLRILNTESDRLTIAWN--P 387
Y F V A NGVS L + ++ + K+R+ + L+++W+ P
Sbjct: 405 HMNYTFTVEARNGVSGLVTSRSFRTASVSINQ----TEPPKVRLEGRSTTSLSVSWSIPP 460
Query: 388 PQVDLTDPDDTIESYEVKCFPKDSQDKNTNTTLRITKDPQVTITGLRKDTEYGIRVRAKM 447
PQ + YEV + K + N +R T+ VT+ L DT Y ++V+A
Sbjct: 461 PQ------QSRVWKYEV-TYRKKGDSNSYN--VRRTEGFSVTLDDLAPDTTYLVQVQALT 511
Query: 448 KRGWGEFSGIVYARTNSVTETSFIDEEGAQXXXXXXXXXXXXXXXXXXXXXXXXFLRSRA 507
+ G G S V E + EG+ F+ R
Sbjct: 512 QEGQGAGS--------KVHEFQTLSPEGS-GNLAVIGGVAVGVVLLLVLAGVGFFIHRRR 562
Query: 508 DDECDKKQPSDCNALNYRNGEVYTGPDRPAKTSSNATTPLFAGTGSRTYIDPHTYEDPNQ 567
++ ++ P D VY + S PL TY D PNQ
Sbjct: 563 KNQRARQSPED----------VYF-------SKSEQLKPLKTYVDPHTYED------PNQ 599
Query: 568 AVREFAREIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARR 627
AV +F EI SC+T + +IG GEFG+V +G LK +S E+ VAIKTLK G TE+ R
Sbjct: 600 AVLKFTTEIHPSCVTRQKVIGAGEFGEVYKGMLK-TSSGKKEVPVAIKTLKAGYTEKQRV 658
Query: 628 DFLAEASIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFRVLQLVG 687
DFL EA IMGQF H N+I L+GV++K P+MIITE+MENG+LD FLR DG+F VLQLVG
Sbjct: 659 DFLGEAGIMGQFSHHNIIRLEGVISKYKPMMIITEYMENGALDKFLREKDGEFSVLQLVG 718
Query: 688 MLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGGK 747
MLRGIA GM+YL+ MNY+HRDLAARN+LVNS LVCK++DFGLSR +E + YTT GGK
Sbjct: 719 MLRGIAAGMKYLANMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEATYTTSGGK 778
Query: 748 IPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPA 807
IP+RWTAPEAI++RKFTSASDVWS GIV WEVM++GERPYW SN +V+K+I G+RLP
Sbjct: 779 IPIRWTAPEAISYRKFTSASDVWSFGIVMWEVMTYGERPYWELSNHEVMKAINDGFRLPT 838
Query: 808 PMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLIRCPDTLRKIA--QNRSADPLAGD 865
PMDCP A+YQLM+ CWQ+ER RP F+ IV LDKLIR PD+L+ +A R + L
Sbjct: 839 PMDCPSAIYQLMMQCWQQERARRPKFADIVSILDKLIRAPDSLKTLADFDPRVSIRLPST 898
Query: 866 T-PDLIQFTSVEEWLECIKMSRYIEKFRAAGISDMDAVVDLTVHQLASLGVTLVGHQKKI 924
+ + + F +V EWLE IKM +Y E F AAG + ++ VV +T + +GV L GHQK+I
Sbjct: 899 SGSEGVPFRTVSEWLESIKMQQYTEHFMAAGYTAIEKVVQMTNDDIKRIGVRLPGHQKRI 958
Query: 925 MNSVQSMRAQIRGSG 939
S+ ++ Q+ G
Sbjct: 959 AYSLLGLKDQVNTVG 973
>UniRef50_UPI0000660568 Cluster: Ephrin type-B receptor 2 precursor
(EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3)
(DRT) (Receptor protein-tyrosine kinase HEK5) (ERK)
(Renal carcinoma antigen NY-REN-47).; n=2; Takifugu
rubripes|Rep: Ephrin type-B receptor 2 precursor (EC
2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (DRT)
(Receptor protein-tyrosine kinase HEK5) (ERK) (Renal
carcinoma antigen NY-REN-47). - Takifugu rubripes
Length = 1071
Score = 671 bits (1657), Expect = 0.0
Identities = 356/747 (47%), Positives = 455/747 (60%), Gaps = 37/747 (4%)
Query: 210 CAPGKFKSHTGDEHCIPCPDHSESTIYAAAECKCTPKYYRAKKDPKTIPCTQPPSAPDNL 269
C G FK+ GDE C CP +S +T A C C YYR DP+ +PCT PSAP ++
Sbjct: 340 CLSGFFKAAQGDEKCQQCPMNSRTTNEGATNCVCRSGYYRTDADPQQMPCTTVPSAPRSV 399
Query: 270 TVTFADQFSISLTWQPPHNTGGRSDITYKI----------SCANCGPTVEFRPGETGLNS 319
++ ++ S+ L W PP GGR D+ Y I C CG V+F P + GL
Sbjct: 400 -ISIVNETSLRLEWSPPQEGGGREDVVYNIICKSCGSGRGGCTRCGDNVQFVPRQLGLMD 458
Query: 320 TRVTISGLDPVTEYKFQVYAENGVSELSPDPANHIEITAVTEAXXXXXXXKLRILNTESD 379
T V IS L T+Y F++ A NGVS+ SP + T + +N
Sbjct: 459 THVHISDLLAHTQYTFEIQAVNGVSDQSPYSPQFASVNITTNQAAPSAVSIIHQVNRSPT 518
Query: 380 RLTIAWNPPQVDLTDPDDTIESYEVKCFPKDSQDKNTNTTLRITKDPQVTITGLRKDTEY 439
+T++W+ P P+ I YE++ + K+ + N + T T I GL+ T Y
Sbjct: 519 SITLSWSQPD----QPNGVILEYELQYYEKNQAEWNASLTKSQTNT--AVIRGLKSGTIY 572
Query: 440 GIRVRAKMKRGWGEFSGIVYARTNSVTE-TSFIDEEGAQXXXXXXXXXXXXXXXXXXXXX 498
+VRA+ G+G FSG +Y +T + E S I E+
Sbjct: 573 VFQVRARTVAGFGRFSGKMYFQTMTEEEYNSSIHEKLPLIIGSAAAGLVFIIAVTVLIIV 632
Query: 499 XXXFLRSRADDE-CDKKQP------SDCNALNYRNGEVYTGPDRPAKTSSNATTPLFA-- 549
R D E DK Q S L + + SS LF
Sbjct: 633 CRRRSSERTDSEYTDKLQQHYTSGHSKAEVLLVELQLLLLLSVARSLYSSCCLFRLFVEV 692
Query: 550 GTGSRTYIDPHTYEDPNQAVREFAREIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPE 609
G + YIDP TYEDPN+AVREFA+EID SC+ IE +IG GEFG+VC G L+ P E
Sbjct: 693 SPGMKIYIDPFTYEDPNEAVREFAKEIDISCVKIEQVIGAGEFGEVCSGNLRQPGK--RE 750
Query: 610 IDVAIKTLKPGSTERARRDFLAEASIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSL 669
I VAIKTLK G TER RRDFL+EASIMGQF+HPN+I L+GVVTK +P+MIITEFMENGSL
Sbjct: 751 ILVAIKTLKVGYTERQRRDFLSEASIMGQFDHPNIIHLEGVVTKSSPVMIITEFMENGSL 810
Query: 670 DTFLRANDGKFRVLQLVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGL 729
D+FLR NDG+F V+QLVGMLRGIA G++YL +MNY+HRDLAARN+LVNS LVCK++DFGL
Sbjct: 811 DSFLRQNDGQFTVIQLVGMLRGIAAGVKYLCDMNYVHRDLAARNILVNSNLVCKVSDFGL 870
Query: 730 SREIE-STADGAYTTR-GGKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPY 787
SR +E T+D YT+ GGKIP+RWTAPEAI +RKFTS+SD WS GIV WEVMS+GERPY
Sbjct: 871 SRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRKFTSSSDCWSYGIVMWEVMSYGERPY 930
Query: 788 WNWSNQDVIKSIEKGYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLIRCP 847
W+ SNQDVI +IE+ YRLP PMDCP A++QLMLDCWQKER +RP FS IV TLDK+IR P
Sbjct: 931 WDMSNQDVINAIEQDYRLPPPMDCPSALHQLMLDCWQKERNNRPKFSQIVSTLDKMIRNP 990
Query: 848 DTLRKIAQNRSADPLAGDTPDLIQFTSVEEWLECIKMSRYIEKFRAAGISDMDAVVDLTV 907
++L+ + PL+ TPD F++V+EWL+ IKM +Y E F + G + + V +T+
Sbjct: 991 NSLKAMT------PLSSSTPDFSSFSTVDEWLDAIKMGQYKENFASEGFTSFEMVSQMTM 1044
Query: 908 HQLASLGVTLVGHQKKIMNSVQSMRAQ 934
+ +GVTL GHQKKI+NS+Q MRAQ
Sbjct: 1045 EDILRVGVTLAGHQKKILNSIQLMRAQ 1071
Score = 132 bits (319), Expect = 4e-29
Identities = 72/167 (43%), Positives = 96/167 (57%), Gaps = 10/167 (5%)
Query: 48 SCKETFSLLYYEFD--VATREQPPWEPESYKLVGRIAAGEG--RFNTNSEV-DINTEVKS 102
SCKETF+L YYE D AT PPW + V IAA E + + + IN+EV+S
Sbjct: 72 SCKETFNLYYYESDSDTATPSSPPWMENPWVKVDTIAADESFSQVDLGGRIMKINSEVRS 131
Query: 103 IA-VTKKGVYFAFRDQGACISILAVKVYYITCPDVNINFARFPATPTGREVTVIEQANGT 161
V++ G Y AF+D GAC+S++AV+V+Y CP V N A FP T +G E T + A G
Sbjct: 132 FGPVSRNGFYLAFQDYGACMSLIAVRVFYRKCPRVIQNGAVFPETLSGAESTSLVAARGV 191
Query: 162 CVANAEVAPGEKAPVYL-CKGDGKWTLPSGSCKCRAGFEPDHNNQIC 207
CV N E P+ L C G+G+W +P G C C+AG++P N C
Sbjct: 192 CVPNGEEV---DVPIKLYCNGEGEWMVPIGRCMCKAGYQPVENATAC 235
>UniRef50_UPI000065F647 Cluster: Ephrin type-B receptor 2 precursor
(EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3)
(DRT) (Receptor protein-tyrosine kinase HEK5) (ERK)
(Renal carcinoma antigen NY-REN-47).; n=1; Takifugu
rubripes|Rep: Ephrin type-B receptor 2 precursor (EC
2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (DRT)
(Receptor protein-tyrosine kinase HEK5) (ERK) (Renal
carcinoma antigen NY-REN-47). - Takifugu rubripes
Length = 986
Score = 663 bits (1638), Expect = 0.0
Identities = 351/745 (47%), Positives = 461/745 (61%), Gaps = 50/745 (6%)
Query: 206 ICTECAPGKFKSHTGDEHCIPCPDHSESTIYAAAECKCTPKYYRAKKDPKTIPCTQPPSA 265
+ C G FK GDE C+ CP +S +T A C C YYR DP +PCT PSA
Sbjct: 276 VVMSCPSGFFKPTQGDEPCMQCPINSRTTSEGAINCVCRNGYYRTDSDPLQMPCTTVPSA 335
Query: 266 PDNLTVTFADQFSISLTWQPPHNTGGRSDITYKI----------SCANCGPTVEFRPGET 315
P ++ ++ ++ S+ L W PP ++GGR D+ + I C CG V+F P +
Sbjct: 336 PQSV-ISSVNETSVMLEWLPPRDSGGREDVVFNIICKSCGGGRGGCTRCGDNVQFLPRQL 394
Query: 316 GLNSTRVTISGLDPVTEYKFQVYAENGVSELSPDPANHIEITAVTEAXXXXXXXKLRILN 375
GL TRV IS L T+Y F+V A NGVS+ SP + + T R +
Sbjct: 395 GLTETRVYISDLLAHTQYTFEVQAVNGVSDQSPYSPQYASVNITTNQAVSIMHQVSRTV- 453
Query: 376 TESDRLTIAWNPPQVDLTDPDDTIESYEVKCFPKDSQDKNTNTTLRITKDPQVTITGLRK 435
D +T++W+ P P+ I YE++ + KD + N+ T +R + V I GL++
Sbjct: 454 ---DSITLSWSQPD----QPNGVILDYELQYYEKDHSELNS-TVIRSPTNT-VVIRGLKQ 504
Query: 436 DTEYGIRVRAKMKRGWGEFSGIVYARTNSVTETSFIDEEGAQXXXXXXXXXXXXXXXXXX 495
T Y +VRA+ G+G +SG +Y +T + E SF+ GA
Sbjct: 505 GTIYVFQVRARTVAGFGRYSGKLYFQTMTEGENSFLTFRGATQVFHFYAMTHLITRCDRS 564
Query: 496 XXXXXXFLRSRADDECDKKQPS----DCNALNYRNGEVYTGPDRPAKTSSNATTPLFAGT 551
R + QP + ++ + +G+++ P + TP
Sbjct: 565 STAKVTSSEWRL--RLEPSQPGFTLPNSSSCSVASGQIFVTPSLFFQV-----TP----- 612
Query: 552 GSRTYIDPHTYEDPNQAVREFAREIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEID 611
G + YIDP TYEDPN+AVREFA+EID SC+ IE +IG GEFG+VC G LKLP E+
Sbjct: 613 GMKIYIDPFTYEDPNEAVREFAKEIDISCVKIEQVIGAGEFGEVCSGNLKLPGK--REMF 670
Query: 612 VAIKTLKPGSTERARRDFLAEASIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDT 671
VAIKTLK G TE+ RRDFL+EASIMGQF+HPNVI L+GVVTK +P+MIITEFMENGSLD
Sbjct: 671 VAIKTLKTGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSSPVMIITEFMENGSLDA 730
Query: 672 FLRANDGKFRVLQLVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSR 731
FLR + QLVGMLRGIA+GM+YL++MNY+HRDLAARN+LVNS LVCK++DFGLSR
Sbjct: 731 FLRVS---IHGDQLVGMLRGIASGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSR 787
Query: 732 EIES-TADGAYTTR-GGKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWN 789
+E T+D YT+ GGKIP+RWTAPEAI +RKFTSASDVWS GIV WEVMS+GERPYW+
Sbjct: 788 FLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWD 847
Query: 790 WSNQDVIKSIEKGYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLIRCPDT 849
+NQDVI +IE+ YRLP PMDCP ++QLMLDCWQK+R +RP FS IV LDK+IR P+T
Sbjct: 848 MTNQDVINAIEQDYRLPPPMDCPSTLHQLMLDCWQKDRNNRPKFSQIVNNLDKMIRNPNT 907
Query: 850 LRKIAQNRSADPLAGDTPDLIQFTSVEEWLECIKMSRYIEKFRAAGISDMDAVVDLTVHQ 909
L+ + PL+ PD F++V+EWL+ IKM +Y + F +A + D V +T+
Sbjct: 908 LKAMT------PLSSGIPDFSSFSTVDEWLDAIKMGQYKDSFASADFTTFDVVSQMTMED 961
Query: 910 LASLGVTLVGHQKKIMNSVQSMRAQ 934
+ +GVTL GHQKKI+NSVQ MRAQ
Sbjct: 962 ILRVGVTLAGHQKKILNSVQMMRAQ 986
Score = 130 bits (313), Expect = 2e-28
Identities = 72/167 (43%), Positives = 94/167 (56%), Gaps = 10/167 (5%)
Query: 48 SCKETFSLLYYEFDV--ATREQPPWEPESYKLVGRIAAGEG--RFNTNSEV-DINTEVKS 102
SCKETF+L YYE D ATR P W + V IAA E + + V INTEV+S
Sbjct: 65 SCKETFNLFYYESDADTATRTSPAWMENPWIKVDTIAADESFSQVDLGGRVMKINTEVRS 124
Query: 103 IA-VTKKGVYFAFRDQGACISILAVKVYYITCPDVNINFARFPATPTGREVTVIEQANGT 161
V++ G Y AF+D G C+S++AV+V+Y CP + N A F T +G E T + A G
Sbjct: 125 FGPVSRNGFYLAFQDYGGCMSLIAVRVFYRKCPRIITNGALFQETLSGAESTSLVAARGV 184
Query: 162 CVANAEVAPGEKAPVYL-CKGDGKWTLPSGSCKCRAGFEPDHNNQIC 207
C+ NAE P+ L C GDG+W +P G C C+AG E N +C
Sbjct: 185 CIPNAEEV---DVPIKLYCNGDGEWMVPIGRCVCKAGNEAVENGTVC 228
>UniRef50_Q4H3M5 Cluster: Ephrin receptor; n=1; Ciona
intestinalis|Rep: Ephrin receptor - Ciona intestinalis
(Transparent sea squirt)
Length = 1002
Score = 646 bits (1595), Expect = 0.0
Identities = 359/905 (39%), Positives = 512/905 (56%), Gaps = 53/905 (5%)
Query: 49 CKETFSLLYY--EFDVATREQPPWEPESYKLVGRIAAGEGRFNTNSEVDINTEVKSIAV- 105
C+ETF+L YY D AT PPW Y + +AAGE RF++ + K++ +
Sbjct: 99 CRETFALYYYPSSSDTATTTFPPWRENPYIKIDTLAAGE-RFDSETVGAEGINKKTLVIG 157
Query: 106 --TKKGVYFAFRDQGACISILAVKVYYITCPDVNINFARFPATPTGREVTVIEQANGTCV 163
+++G Y A +DQGAC+SI+++K+YY C + N A FP T +G + + +G CV
Sbjct: 158 PLSRRGFYIAAQDQGACMSIMSLKLYYYHCEETTHNLAYFPNTISGGGIAELVSQSGKCV 217
Query: 164 ANAEVAPGEKAPVYLCKGDGKWTLPSGSCKCRAGFEPDHNNQICTECAPGKFKSHTGDEH 223
+N+ A + P Y C G+W +P+GSC+CRAG+EP+ CT C GK+KS G+
Sbjct: 218 SNSVYA--NEVPKYRCNIYGEWQVPTGSCQCRAGYEPNTQLTACTGCMVGKYKSTNGNTP 275
Query: 224 CIPCPDHSESTIYAAAECKCTPKYYRAKKDPKTIPCTQPPSAPDNLTVTFADQFSISLTW 283
C CP HS + +A+ C C +YRA+ DP + CT+PP+ P N+T ++ S+ L+W
Sbjct: 276 CQVCPQHSVTHSTSASHCTCVAGHYRAENDPISQACTRPPTKPRNVTHV-QNKTSLLLSW 334
Query: 284 QPPHNTGGRSDITYKISCA-------NCGPT---VEFRPGE-TGLNSTRVTISGLDPVTE 332
PP TGGR+DI Y ISC NC P V++RP +T + +S L+P +
Sbjct: 335 VPPSTTGGRTDIYYSISCELCDSEHENCQPCNVDVQYRPSNHQHTTTTYMEVSNLNPFSC 394
Query: 333 YKFQVYAENGVSELSPDPANHIEITAVTEAXXXXXXXKLRILNTESDRLTIAWNPPQVDL 392
YKF+V + NGVS +S +P I T A L+ + T++W PP
Sbjct: 395 YKFKVSSSNGVSRVSVEPEQFELIKICTNAAAPSAVTGLKFIWIGEVSATLSWLPPT--- 451
Query: 393 TDPDDTIESYEVKCFPKDSQDKNTNTTLRITKDPQVTITGLRKDTEYGIRVRAKMKRGWG 452
+ I YEV+ F + + K T + P VTI GL +Y + VRA G G
Sbjct: 452 --HSNKIVGYEVQLFQNNQRLKLTK--IMEVSTPNVTINGLNPGWKYVVMVRACNNDGCG 507
Query: 453 EFSGIVYARTNSVTETSFIDEEGAQXXXXXXXXXXXXXXXXXXXXXXXXFLRSRADDECD 512
+FS + VT + E ++ R + D
Sbjct: 508 QFS----EKLQLVTYDKGSEPESIVEGSTTWIGGVIGGVLVIVIIIIVVMIKRR---QTD 560
Query: 513 KKQPSDCNALNYRNGEVYTGPDRPAKTSSNATTPLFAGTGSRTYIDPHTYEDPNQAVREF 572
KK+ + A N + + F T RTY+D Y DP+ V+E
Sbjct: 561 KKKRKEIQARTKLN-----------ENTQQLNQSSFLQTAGRTYVD---YRDPHNGVKEI 606
Query: 573 AREIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAE 632
A EID + I I+++IG GEFG+VCRGK+ + VA+K LK G++ +FL E
Sbjct: 607 ATEIDQTRIKIDSVIGRGEFGEVCRGKMLTGKTT---TSVAVKRLKHGASLIDHTNFLRE 663
Query: 633 ASIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFRVLQLVGMLRGI 692
A M QF+ PN+I L+GVVTK P MIITEFME+GSLD FL+A G+ VLQL+ MLRGI
Sbjct: 664 ACTMAQFKDPNIIQLKGVVTKSIPAMIITEFMEHGSLDKFLQARSGQPTVLQLLEMLRGI 723
Query: 693 ATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGGKIPVRW 752
A+GM+YLS M Y+HRDLAARN+LVNSQLVCK++DFGLSR +E+ YTT+GGKI +RW
Sbjct: 724 ASGMKYLSSMKYVHRDLAARNILVNSQLVCKVSDFGLSRTLENDPQATYTTQGGKIALRW 783
Query: 753 TAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCP 812
TAPE+I R+FTSASDVWS GIV WEVMS+GE+PYW+ SN+ V + +E GYRLP+P CP
Sbjct: 784 TAPESIRCRQFTSASDVWSYGIVMWEVMSYGEKPYWDMSNEVVTEVLEDGYRLPSPEGCP 843
Query: 813 EAVYQLMLDCWQKERTHRPTFSSIVKTLDKLIRCPDTLR-KIAQNRSADPLAGDTPDLIQ 871
V+ LML CW E RPT I+KTLD I+ P +L+ + + SA L D+P+ IQ
Sbjct: 844 TPVHSLMLKCWSYEPKRRPTLLEIIKTLDHFIKQPSSLQDDMEADASAPLLKPDSPNSIQ 903
Query: 872 -FTSVEEWLECIKMSRYIEKFRAAGISDMDAVVDLTVHQLASLGVTLVGHQKKIMNSVQS 930
++++EWL+ +K+ RY F GI+D++++ ++ +L LG+ H+ ++ + +
Sbjct: 904 DVSTLDEWLDMVKLGRYRRSFHNNGINDLESLAHISESELDRLGIASPSHRTRLQGGINT 963
Query: 931 MRAQI 935
+R +
Sbjct: 964 LRQHL 968
>UniRef50_Q4SUM3 Cluster: Ephrin receptor; n=4; Tetraodon
nigroviridis|Rep: Ephrin receptor - Tetraodon
nigroviridis (Green puffer)
Length = 1173
Score = 632 bits (1562), Expect = e-179
Identities = 358/813 (44%), Positives = 464/813 (57%), Gaps = 54/813 (6%)
Query: 48 SCKETFSLLYYEFD--VATREQPPWEPESYKLVGRIAAGEG--RFNTNSEV-DINTEVKS 102
SCKETF+L YYE D A+ P W + V IAA E + + + IN+EV+S
Sbjct: 88 SCKETFNLYYYESDSDTASGSSPAWMENPWVKVDTIAADESFSQVDLGGRIMKINSEVRS 147
Query: 103 IA-VTKKGVYFAFRDQGACISILAVKVYYITCPDVNINFARFPATPTGREVTVIEQANGT 161
V++ G Y AF+D GAC+S++AV+V+Y CP V N A F T +G E T + A G
Sbjct: 148 FGPVSRNGFYLAFQDYGACMSLIAVRVFYRKCPRVIQNGAVFAETLSGAESTSLVAARGV 207
Query: 162 CVANAEVAPGEKAPVYL-CKGDGKWTLPSGSCKCRAGFEPDHNNQICTECAPGKFKSHTG 220
CV N E P+ L C GDG+W +P G C CRAGF+P N C C G FK+ G
Sbjct: 208 CVPNGEEVD---VPIKLYCNGDGEWMVPIGRCMCRAGFQPVENATACRACPSGFFKAAQG 264
Query: 221 DEHCIPCPDHSESTIYAAAECKCTPKYYRAKKDPKTIPCTQPPSAPDNLTVTFADQFSIS 280
D+ C CP +S ++ A C C YYR DP+ +PCT PSAP ++ ++ ++ S+
Sbjct: 265 DDRCQQCPLNSRTSSEGATSCVCRSGYYRTDADPQQMPCTTVPSAPRSV-ISMVNETSLR 323
Query: 281 LTWQPPHNTGGRSDITYKI----------SCANCGPTVEFRPGETGLNSTRVTISGLDPV 330
L W PP GGR D+ Y I C CG V+F P + GL TRV +S L
Sbjct: 324 LEWSPPQEGGGREDVVYNIICKSCGSGRGGCTRCGDNVQFVPRQLGLTDTRVHVSELLAH 383
Query: 331 TEYKFQVYAENGVSELSPDPANHIEITAVTEAXXXXXXXKLRILNTESDRLTIAWNPP-Q 389
T+Y F++ A NGVS+ SP + + T + ++ +T++W+ P Q
Sbjct: 384 TQYTFEIQAVNGVSDQSPYSPQYASVNITTNQAAPSAVSIIHQVSRSPTSITLSWSQPDQ 443
Query: 390 VDLTDPDDTIESYEVKCFPKDSQDKNT----------------NTTLRITKDPQVTITGL 433
+ + ++ YE C + +T N ++ ++ I GL
Sbjct: 444 PNGVILEYELQYYEKVCHTRAHTRMHTHPGVQQLICLQNQAEWNASVTTSQTNTAVIRGL 503
Query: 434 RKDTEYGIRVRAKMKRGWGEFSGIVYARTNSVTETSFIDEEGAQXXXXXXXXXXXXXXXX 493
R + Y +VRA+ G+G FSG +Y +T + E + +E
Sbjct: 504 RPGSIYVFQVRARTVAGFGRFSGKMYFQTMTEEEYNSSIQEKLPLIIGSAAAGLVFVLAV 563
Query: 494 XXXXXXXXFLRS--RADDE-CDKKQ----PSDCNALNYRNGEVYTG-PDRPAKTSSNATT 545
RS R D E DK Q L G G RP +S
Sbjct: 564 TVLIIVCRSRRSSDRTDSEYTDKLQQHYTSGRSKCLQLLRGCSRPGCSSRPCLDTSRCLL 623
Query: 546 PLF--AGTGSRTYIDPHTYEDPNQAVREFAREIDASCITIEAIIGGGEFGDVCRGKLKLP 603
PL A G + YIDP TYEDPN+AVREFA+EID SC+ IE +IG GEFG+VC G L+ P
Sbjct: 624 PLCVEASPGMKIYIDPFTYEDPNEAVREFAKEIDISCVKIEQVIGAGEFGEVCSGNLRQP 683
Query: 604 ASCGPEIDVAIKTLKPGSTERARRDFLAEASIMGQFEHPNVIFLQGVVTKCNPIMIITEF 663
EI VAIKTLK G TER RRDFL+EASIMGQF+HPN+I L+GVVTK +P+MIITEF
Sbjct: 684 GK--REILVAIKTLKVGYTERQRRDFLSEASIMGQFDHPNIIHLEGVVTKSSPVMIITEF 741
Query: 664 MENGSLDTFLRANDGKFRVLQLVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCK 723
MENGSLD+FLR NDG+F V+QLVGMLRGIA G++YL +MNY+HRDLAARN+LVNS LVCK
Sbjct: 742 MENGSLDSFLRQNDGQFTVIQLVGMLRGIAAGVKYLCDMNYVHRDLAARNILVNSNLVCK 801
Query: 724 IADFGLSREIE-STADGAYTTR-GGKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMS 781
++DFGLSR +E T+D YT+ GGKIP+RWTAPEAI +RKFTS+SD WS GIV WEVMS
Sbjct: 802 VSDFGLSRFLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRKFTSSSDCWSYGIVMWEVMS 861
Query: 782 FGERPYWNWSNQDVIKSIEKG--YRLPAPMDCP 812
+GERPYW+ SNQDV ++ G YRL P P
Sbjct: 862 YGERPYWDMSNQDVSRNAGLGSVYRLTGPRAPP 894
>UniRef50_UPI0000E47549 Cluster: PREDICTED: similar to Cek8; n=2;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
Cek8 - Strongylocentrotus purpuratus
Length = 775
Score = 621 bits (1535), Expect = e-176
Identities = 334/748 (44%), Positives = 438/748 (58%), Gaps = 30/748 (4%)
Query: 209 ECAPGKFKSHTGDEHCIPCPDHSESTIYAAAECKCTPKYYRAKKDPKTIPCTQPPSAPDN 268
+C G FKS G C PCP S + A C C P YYRA + + PCT PPSAP +
Sbjct: 29 KCQIGTFKSDIGTTECSPCPAKSHADTVAVTRCTCIPDYYRAPGEEASSPCTAPPSAPTS 88
Query: 269 LTVTFADQFS-ISLTWQPPHNTGGRSDITYKISCANCGPTVEFRPGETGLNSTRVTISGL 327
LT ++ S ++LTW+ P N GGR+DI ++I C C V+F + V +S L
Sbjct: 89 LTAVVDEKSSVVTLTWRNPENLGGRTDIDFRIDCKRCPADVQFSSIQRIGQGYEVNVSRL 148
Query: 328 DPVTEYKFQVYAENGVSELSPDPANHIEITAVTEAXXXXXXXKLRIL--NTESDRLTIAW 385
T Y+F+V++ N VS N+ + A T + L+++ + + + + W
Sbjct: 149 SSHTTYEFKVHSYNEVSS-QGTVDNYAGVNATTFSSVPSAVRDLKVVEDDVNDESIKLRW 207
Query: 386 NPPQVDLTDPDDTIESYEVKCFPKDSQDKNTNTTLRITKDPQV---TITGLRKDTEYGIR 442
P P+ I +Y+V +N + D +V T+ GL TEY
Sbjct: 208 RQPLF----PNGEITNYQVIYRTSAETQENVKYHYQAVLDGEVQETTVHGLVPGTEYVFE 263
Query: 443 VRAKMKRGWGEFSGIVYARTN---SVTETSFIDEEGAQXXXXXXXXXXXXXXXXXXXXXX 499
V A G G +S V A ++ + + I
Sbjct: 264 VAANTASGVGAYSQQVLATSSGSGGQSVPTVILAAAVSAIFIIVVLVAVVIFLVFWRRKS 323
Query: 500 XXFLRSRADDECDKKQPSDCNALNYRNGEVYTGPDRPAKTSSNATTPLFAGTGSR-TYID 558
LR + A ++ T P R + + L G+ I
Sbjct: 324 LKQLRKGMSQTGPDASKARWKAKQQLYYQISTLPPRKKEVPPSENGHLIYANGTNGEVIL 383
Query: 559 PH-----TYED------PNQAVREFAREIDASCITIEAIIGGGEFGDVCRGKLKLPASCG 607
PH TY D PNQAV+EFA EIDA+ I I +IGGGEFGDVC G + +P
Sbjct: 384 PHIKKVKTYVDPFTYEDPNQAVKEFATEIDATQIRILEVIGGGEFGDVCSGLMLMPDK-- 441
Query: 608 PEIDVAIKTLKPGSTERARRDFLAEASIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENG 667
I VA+KTLK G+T++ R DFL+EASIMGQF+HPNVI L GVVTK P MI+TEFMENG
Sbjct: 442 TTIKVAVKTLKTGATDKDRSDFLSEASIMGQFDHPNVIKLLGVVTKTRPAMIVTEFMENG 501
Query: 668 SLDTFLRANDGKFRVLQLVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADF 727
SLD +LR NDG+F V QL+GM+RG+ GM++LSEMN++HRDLAARN+LVN LVCK+ADF
Sbjct: 502 SLDKYLRENDGRFTVTQLLGMMRGVGFGMRFLSEMNFVHRDLAARNILVNEHLVCKVADF 561
Query: 728 GLSREIESTADGAYTTRGGKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPY 787
GLSR E DGAY TRGGKIP+RWTAPEAI ++KFTSASDVWS+G+V WE+MS+GERPY
Sbjct: 562 GLSRRKE--LDGAYETRGGKIPIRWTAPEAIGYKKFTSASDVWSLGVVMWEIMSYGERPY 619
Query: 788 WNWSNQDVIKSIEKGYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLIRCP 847
WNW NQDVIK++EKGYRLP PM+CPEA++QLMLDCWQ++R HRPTF++IV TLD+LIR P
Sbjct: 620 WNWPNQDVIKAVEKGYRLPPPMECPEAIHQLMLDCWQRDRNHRPTFTTIVSTLDRLIRNP 679
Query: 848 DTLRKIAQNRSADPLAGDTPDLIQFTSVEEWLECIKMSRYIEKFRAAGISDMDAVVDLTV 907
+ LR +A+N S L+ DL +F SV +WL+ +KM RY + F AAG ++ + L+
Sbjct: 680 NALRPLAKNGSPLGLSSSLNDLSRFNSVSDWLDSLKMGRYKDSFTAAGYVRLEDIARLSQ 739
Query: 908 HQLASLGVTLVGHQKKIMNSVQSMRAQI 935
L LGVTL GHQKKIM + S+RAQ+
Sbjct: 740 SDLPRLGVTLAGHQKKIMKGIHSIRAQL 767
>UniRef50_Q15375 Cluster: Ephrin type-A receptor 7 precursor; n=51;
Euteleostomi|Rep: Ephrin type-A receptor 7 precursor -
Homo sapiens (Human)
Length = 998
Score = 550 bits (1357), Expect = e-155
Identities = 255/391 (65%), Positives = 312/391 (79%), Gaps = 5/391 (1%)
Query: 548 FAGTGSRTYIDPHTYEDPNQAVREFAREIDASCITIEAIIGGGEFGDVCRGKLKLPASCG 607
F G++TYIDP TYEDPN+AV +FA+E+DASCI IE +IG GEFG+VC G+LKLP
Sbjct: 600 FKFPGTKTYIDPETYEDPNRAVHQFAKELDASCIKIERVIGAGEFGEVCSGRLKLPGK-- 657
Query: 608 PEIDVAIKTLKPGSTERARRDFLAEASIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENG 667
++ VAIKTLK G TE+ RRDFL EASIMGQF+HPNV+ L+GVVT+ P+MI+ EFMENG
Sbjct: 658 RDVAVAIKTLKVGYTEKQRRDFLCEASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENG 717
Query: 668 SLDTFLRANDGKFRVLQLVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADF 727
+LD FLR +DG+F V+QLVGMLRGIA GM+YL++M Y+HRDLAARN+LVNS LVCK++DF
Sbjct: 718 ALDAFLRKHDGQFTVIQLVGMLRGIAAGMRYLADMGYVHRDLAARNILVNSNLVCKVSDF 777
Query: 728 GLSREIESTADGAYTTRGGKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPY 787
GLSR IE + YTT GGKIPVRWTAPEAI +RKFTSASDVWS GIV WEVMS+GERPY
Sbjct: 778 GLSRVIEDDPEAVYTTTGGKIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPY 837
Query: 788 WNWSNQDVIKSIEKGYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLIRCP 847
W+ SNQDVIK+IE+GYRLPAPMDCP ++QLMLDCWQKER RP F IV LDK+IR P
Sbjct: 838 WDMSNQDVIKAIEEGYRLPAPMDCPAGLHQLMLDCWQKERAERPKFEQIVGILDKMIRNP 897
Query: 848 DTLRKI--AQNRSADPLAG-DTPDLIQFTSVEEWLECIKMSRYIEKFRAAGISDMDAVVD 904
++L+ +R PL +TPD F SV EWL+ IKM RY + F AAG + +++V
Sbjct: 898 NSLKTPLGTCSRPISPLLDQNTPDFTTFCSVGEWLQAIKMERYKDNFTAAGYNSLESVAR 957
Query: 905 LTVHQLASLGVTLVGHQKKIMNSVQSMRAQI 935
+T+ + SLG+TLVGHQKKIM+S+Q+MRAQ+
Sbjct: 958 MTIEDVMSLGITLVGHQKKIMSSIQTMRAQM 988
Score = 263 bits (644), Expect = 2e-68
Identities = 149/422 (35%), Positives = 218/422 (51%), Gaps = 26/422 (6%)
Query: 48 SCKETFSLLYYEFDVATREQPPWEPESYKLVGRIAAGEGRFNTN---SEVDINTEVKSIA 104
+CKETF+L YYE D T Y + IAA E + ++ +NTEV+ I
Sbjct: 118 TCKETFNLYYYETDYDTGRNI--RENLYVKIDTIAADESFTQGDLGERKMKLNTEVREIG 175
Query: 105 -VTKKGVYFAFRDQGACISILAVKVYYITCPDVNINFARFPATPTGREVTVIEQANGTCV 163
++KKG Y AF+D GACI++++VKVYY C + N A FP T TG E + + + GTCV
Sbjct: 176 PLSKKGFYLAFQDVGACIALVSVKVYYKKCWSIIENLAIFPDTVTGSEFSSLVEVRGTCV 235
Query: 164 ANAEVAPGEKAPVYLCKGDGKWTLPSGSCKCRAGFEPDHNNQICTECAPGKFKSHTGDEH 223
++AE E AP C +G+W +P G C C+AG++ C C G +KS + D
Sbjct: 236 SSAE-EEAENAPRMHCSAEGEWLVPIGKCICKAGYQ--QKGDTCEPCGRGFYKSSSQDLQ 292
Query: 224 CIPCPDHSESTIYAAAECKCTPKYYRAKKDPKTIPCTQPPSAPDNLTVTFADQFSISLTW 283
C CP HS S ++ C+C YYRA DP + CT+PPSAP NL +Q ++SL W
Sbjct: 293 CSRCPTHSFSDKEGSSRCECEDGYYRAPSDPPYVACTRPPSAPQNLIFNI-NQTTVSLEW 351
Query: 284 QPPHNTGGRSDITYKI----------SCANCGPTVEFRPGETGLNSTRVTISGLDPVTEY 333
PP + GGR+D+TY+I C CG + + P +TGL VT+ L Y
Sbjct: 352 SPPADNGGRNDVTYRILCKRCSWEQGECVPCGSNIGYMPQQTGLEDNYVTVMDLLAHANY 411
Query: 334 KFQVYAENGVSELSPDPANHIEITAVTEAXXXXXXXKLRILNTESDRLTIAWNPPQVDLT 393
F+V A NGVS+LS ++ T + + ++W P+
Sbjct: 412 TFEVEAVNGVSDLSRSQRLFAAVSITTGQAAPSQVSGVMKERVLQRSVELSWQEPE---- 467
Query: 394 DPDDTIESYEVKCFPKDSQDKNTNTTLRITKDPQVTITGLRKDTEYGIRVRAKMKRGWGE 453
P+ I YE+K + KD +++ T +T++ TK +I L+ T Y ++RA G+G
Sbjct: 468 HPNGVITEYEIKYYEKDQRER-TYSTVK-TKSTSASINNLKPGTVYVFQIRAFTAAGYGN 525
Query: 454 FS 455
+S
Sbjct: 526 YS 527
>UniRef50_P29323 Cluster: Ephrin type-B receptor 2 precursor; n=311;
Eumetazoa|Rep: Ephrin type-B receptor 2 precursor - Homo
sapiens (Human)
Length = 1055
Score = 543 bits (1341), Expect = e-153
Identities = 258/389 (66%), Positives = 308/389 (79%), Gaps = 7/389 (1%)
Query: 552 GSRTYIDPHTYEDPNQAVREFAREIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEID 611
G + YIDP TYEDPN+AVREFA+EID SC+ IE +IG GEFG+VC G LKLP EI
Sbjct: 592 GMKIYIDPFTYEDPNEAVREFAKEIDISCVKIEQVIGAGEFGEVCSGHLKLPGK--REIF 649
Query: 612 VAIKTLKPGSTERARRDFLAEASIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDT 671
VAIKTLK G TE+ RRDFL+EASIMGQF+HPNVI L+GVVTK P+MIITEFMENGSLD+
Sbjct: 650 VAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDS 709
Query: 672 FLRANDGKFRVLQLVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSR 731
FLR NDG+F V+QLVGMLRGIA GM+YL++MNY+HRDLAARN+LVNS LVCK++DFGLSR
Sbjct: 710 FLRQNDGQFTVIQLVGMLRGIAAGMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSR 769
Query: 732 EIE-STADGAYTTR-GGKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWN 789
+E T+D YT+ GGKIP+RWTAPEAI +RKFTSASDVWS GIV WEVMS+GERPYW+
Sbjct: 770 FLEDDTSDPTYTSALGGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWD 829
Query: 790 WSNQDVIKSIEKGYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLIRCPDT 849
+NQDVI +IE+ YRLP PMDCP A++QLMLDCWQK+R HRP F IV TLDK+IR P++
Sbjct: 830 MTNQDVINAIEQDYRLPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTLDKMIRNPNS 889
Query: 850 LRKIAQNRSAD--PLAGDT-PDLIQFTSVEEWLECIKMSRYIEKFRAAGISDMDAVVDLT 906
L+ +A S PL T PD F +V+EWLE IKM +Y E F AG + D V +
Sbjct: 890 LKAMAPLSSGINLPLLDRTIPDYTSFNTVDEWLEAIKMGQYKESFANAGFTSFDVVSQMM 949
Query: 907 VHQLASLGVTLVGHQKKIMNSVQSMRAQI 935
+ + +GVTL GHQKKI+NS+Q MRAQ+
Sbjct: 950 MEDILRVGVTLAGHQKKILNSIQVMRAQM 978
Score = 289 bits (708), Expect = 3e-76
Identities = 160/437 (36%), Positives = 230/437 (52%), Gaps = 27/437 (6%)
Query: 48 SCKETFSLLYYE--FDVATREQPPWEPESYKLVGRIAAGEG--RFNTNSEV-DINTEVKS 102
SCKETF+L YYE FD AT+ P W + V IAA E + + V INTEV+S
Sbjct: 106 SCKETFNLYYYEADFDSATKTFPNWMENPWVKVDTIAADESFSQVDLGGRVMKINTEVRS 165
Query: 103 IA-VTKKGVYFAFRDQGACISILAVKVYYITCPDVNINFARFPATPTGREVTVIEQANGT 161
V++ G Y AF+D G C+S++AV+V+Y CP + N A F T +G E T + A G+
Sbjct: 166 FGPVSRSGFYLAFQDYGGCMSLIAVRVFYRKCPRIIQNGAIFQETLSGAESTSLVAARGS 225
Query: 162 CVANAEVAPGEKAPVYL-CKGDGKWTLPSGSCKCRAGFEPDHNNQICTECAPGKFKSHTG 220
C+ANAE P+ L C GDG+W +P G C C+AGFE N +C C G FK++ G
Sbjct: 226 CIANAEEVD---VPIKLYCNGDGEWLVPIGRCMCKAGFEAVENGTVCRGCPSGTFKANQG 282
Query: 221 DEHCIPCPDHSESTIYAAAECKCTPKYYRAKKDPKTIPCTQPPSAPDNLTVTFADQFSIS 280
DE C CP +S +T A C C YYRA DP +PCT PSAP ++ ++ S+
Sbjct: 283 DEACTHCPINSRTTSEGATNCVCRNGYYRADLDPLDMPCTTIPSAP-QAVISSVNETSLM 341
Query: 281 LTWQPPHNTGGRSDITYKI----------SCANCGPTVEFRPGETGLNSTRVTISGLDPV 330
L W PP ++GGR D+ Y I +C CG V++ P + GL R+ IS L
Sbjct: 342 LEWTPPRDSGGREDLVYNIICKSCGSGRGACTRCGDNVQYAPRQLGLTEPRIYISDLLAH 401
Query: 331 TEYKFQVYAENGVSELSPDPANHIEITAVTEAXXXXXXXKLRILNTESDRLTIAWNPPQV 390
T+Y F++ A NGV++ SP + T + ++ D +T++W+ P
Sbjct: 402 TQYTFEIQAVNGVTDQSPFSPQFASVNITTNQAAPSAVSIMHQVSRTVDSITLSWSQPD- 460
Query: 391 DLTDPDDTIESYEVKCFPKDSQDKNTNTTLRITKDPQVTITGLRKDTEYGIRVRAKMKRG 450
P+ I YE++ + K+ + N T VT+ GL+ Y +VRA+ G
Sbjct: 461 ---QPNGVILDYELQYYEKELSEYNATAIKSPTN--TVTVQGLKAGAIYVFQVRARTVAG 515
Query: 451 WGEFSGIVYARTNSVTE 467
+G +SG +Y +T + E
Sbjct: 516 YGRYSGKMYFQTMTEAE 532
>UniRef50_Q4SWL0 Cluster: Ephrin receptor; n=3; Tetraodontidae|Rep:
Ephrin receptor - Tetraodon nigroviridis (Green puffer)
Length = 1072
Score = 542 bits (1337), Expect = e-152
Identities = 249/384 (64%), Positives = 317/384 (82%), Gaps = 7/384 (1%)
Query: 552 GSRTYIDPHTYEDPNQAVREFAREIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEID 611
GSRTYI PHTYEDPNQA+R+FA+EIDAS I IE +IG GEFG+VC G+L++ EI
Sbjct: 694 GSRTYIHPHTYEDPNQAIRDFAKEIDASNIRIERVIGAGEFGEVCSGRLRVQGK--REIY 751
Query: 612 VAIKTLKPGSTERARRDFLAEASIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDT 671
VAIK+LK G +++ RRDFL+EASIMGQF+HPN+I L+GVVT+C P+MIITEFMENGSLDT
Sbjct: 752 VAIKSLKAGYSDKQRRDFLSEASIMGQFDHPNIIRLEGVVTRCKPVMIITEFMENGSLDT 811
Query: 672 FLRANDGKFRVLQLVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSR 731
FL+ +DG+F V+QLVGMLRGIA+GM+YLS+M+Y+HRDLAARN+LVNS LVCK++DFGLSR
Sbjct: 812 FLKKHDGQFTVIQLVGMLRGIASGMKYLSDMSYVHRDLAARNILVNSNLVCKVSDFGLSR 871
Query: 732 EIESTADGAYTTRGGKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWS 791
+E + AYTTRGGKIP+RWTAPEAIA+RKFTSASDVWS GIV WEV+S+GERPYW S
Sbjct: 872 VLEDDPEAAYTTRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVISYGERPYWEMS 931
Query: 792 NQDVIKSIEKGYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLIRCPDTLR 851
NQDVIK+I++GYRLPAPMDCP ++QLMLDCW+K R+ RP F IV LDKLIR P +LR
Sbjct: 932 NQDVIKAIDEGYRLPAPMDCPVVLHQLMLDCWEKGRSDRPKFGQIVTILDKLIRNPASLR 991
Query: 852 KIAQNRS-ADPLAGDTPDLIQFTSVEEWLECIKMSRYIEKFRAAGISDMDAVVDLTVHQL 910
++A + + DP A D + +V+EWLE IKM +Y + F ++G +++V+ ++V +L
Sbjct: 992 ELANSSAWEDPTASD----VSVNTVDEWLEAIKMGQYKDNFSSSGYVSLESVLYISVSEL 1047
Query: 911 ASLGVTLVGHQKKIMNSVQSMRAQ 934
A +GVTL GHQKKI++SVQ+++ Q
Sbjct: 1048 AKMGVTLAGHQKKILSSVQNLQTQ 1071
Score = 174 bits (424), Expect = 8e-42
Identities = 96/264 (36%), Positives = 143/264 (54%), Gaps = 21/264 (7%)
Query: 210 CAPGKFKSHTGDEHCIPCPDHSESTIYAAAECKCTPKYYRAKKDPKTIPCTQPPSAPDNL 269
C PG +K+ D +C CP HS S A EC C +YRA+ DP+++ CT+PPS P+N
Sbjct: 325 CRPGTYKASATDAYCTKCPPHSSSPQDQAVECTCEKGFYRAETDPRSMACTRPPSPPEN- 383
Query: 270 TVTFADQFSISLTWQPPHNTGGRSDITYKI----------SCANCGPTVEFRPGETGLNS 319
++ ++ ++L W P +TGGR D+TY I CA CG +V F P + GL +
Sbjct: 384 PISTVNETCVTLEWTLPRDTGGRGDVTYSIHCRKCSGDGRKCAPCGSSVHFVPRQYGLAT 443
Query: 320 TRVTISGLDPVTEYKFQVYAENGVSELSPDPANHIEITAVTEAXXXXXXXKLRILNTESD 379
T V I+ L P + Y F V ++NGVS+LSP P + I VT + K R D
Sbjct: 444 TTVQITDLQPDSNYSFTVESQNGVSDLSPTPRGTV-IVNVTTSQTVSVVLKER---RSKD 499
Query: 380 RLTIAWNPPQVDLTDPDDTIESYEVKCFPKDSQDKNTNTTLRITKDPQVTITGLRKDTEY 439
+T+AW P+ P+ I YEV + K+ +++N T L+ T+ +T+ GL+ T Y
Sbjct: 500 SVTLAWQGPE----RPNGVIVEYEVIYYEKNQREQN-YTVLK-TRSNMMTVEGLKPGTTY 553
Query: 440 GIRVRAKMKRGWGEFSGIVYARTN 463
RVRA+ G+G + G + T+
Sbjct: 554 VFRVRARTDGGYGSYGGEIELETS 577
Score = 110 bits (264), Expect = 2e-22
Identities = 66/174 (37%), Positives = 96/174 (55%), Gaps = 18/174 (10%)
Query: 48 SCKETFSLLYYEFDVATREQPPW--EPESYKLVGRIAAGEG--RFNTNSEV-DINTEVKS 102
+CKETF++ YYE + A W + Y + IAA E + + V +NTEV+
Sbjct: 74 TCKETFNMYYYESNNANL----WFIKESQYVKIDTIAADESFTQVDVGDRVMKLNTEVRD 129
Query: 103 IA-VTKKGVYFAFRDQGACISILAVKVYYITCPDVNINFARFPATPTGREVTVIEQANGT 161
I+ ++KKG Y AF+D GACI++++V+V+Y CP +N A+FP T TG + ++E +G
Sbjct: 130 ISNLSKKGFYLAFQDLGACIALVSVRVFYKKCPLTVLNLAQFPDTITGGDTALVE-VHGV 188
Query: 162 CVANAEVAPGEKAPVYLCKGDGKWTLPSGSCKCRAGFEPDHNNQICTECAPGKF 215
CV +E + P C DG W +P G C C+ GFE N C PG F
Sbjct: 189 CVNASEEF---EVPKMYCSADGGWLVPIGRCVCKPGFE--ENKDFCQR--PGSF 235
>UniRef50_Q6PFV6 Cluster: Ephrin receptor; n=11; Tetrapoda|Rep:
Ephrin receptor - Mus musculus (Mouse)
Length = 819
Score = 521 bits (1286), Expect = e-146
Identities = 243/359 (67%), Positives = 286/359 (79%), Gaps = 5/359 (1%)
Query: 552 GSRTYIDPHTYEDPNQAVREFAREIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEID 611
G RTYIDPHTYEDPNQAV EFA+EI+ASCITIE +IG GEFG+VC G+LKLP E+
Sbjct: 462 GVRTYIDPHTYEDPNQAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGK--RELP 519
Query: 612 VAIKTLKPGSTERARRDFLAEASIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDT 671
VAIKTLK G TE+ RRDFL EASIMGQF+HPN+I L+GVVTK P+MI+TE+MENGSLDT
Sbjct: 520 VAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDT 579
Query: 672 FLRANDGKFRVLQLVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSR 731
FL+ NDG+F V+QLVGMLRGIA GM+YLS+M Y+HRDLAARN+L+NS LVCK++DFGLSR
Sbjct: 580 FLKKNDGQFTVIQLVGMLRGIAAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSR 639
Query: 732 EIESTADGAYTTRGGKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWS 791
+E + AYTTRGGKIP+RWTAPEAIAFRKFTS+SDVWS GIV WEV+S+GERPYW +
Sbjct: 640 VLEDDPEAAYTTRGGKIPIRWTAPEAIAFRKFTSSSDVWSYGIVMWEVVSYGERPYWEMT 699
Query: 792 NQDVIKSIEKGYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLIRCPDTLR 851
NQDVIK++E+GYRLP+PMDCP A+YQLMLDCWQK+R RP F IV LDKLIR P +L+
Sbjct: 700 NQDVIKAVEEGYRLPSPMDCPAALYQLMLDCWQKDRNSRPKFDEIVNMLDKLIRNPSSLK 759
Query: 852 KIAQNRS-ADPLAGDTPDLIQ--FTSVEEWLECIKMSRYIEKFRAAGISDMDAVVDLTV 907
+ S L + L + SV EWLE IKM RY E F G S MDAV +T+
Sbjct: 760 TLVNASSRVSTLLAEHGSLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSMDAVAQVTL 818
Score = 107 bits (256), Expect = 2e-21
Identities = 62/173 (35%), Positives = 94/173 (54%), Gaps = 11/173 (6%)
Query: 44 GNALSCKETFSLLYYEFDVATREQPPWEPESYKLVGRIAAGEG--RFNTNSEV-DINTEV 100
G +CKETF++ Y+E D + Y + IAA E + V +NTEV
Sbjct: 144 GGLGTCKETFNMYYFESDDENGRSI--KENQYIKIDTIAADESFTELDLGDRVMKLNTEV 201
Query: 101 KSIA-VTKKGVYFAFRDQGACISILAVKVYYITCPDVNINFARFPATPTGREVTVIEQAN 159
+ + ++KKG Y AF+D GACI++++V+VYY CP V + A FP T TG + + + + +
Sbjct: 202 RDVGPLSKKGFYLAFQDVGACIALVSVRVYYKKCPSVVRHLAIFPDTITGADSSQLLEVS 261
Query: 160 GTCVANAEVAPGEKAPVYLCKGDGKWTLPSGSCKCRAGFEPDHNNQICTECAP 212
G+CV N V + P C +G+W +P G C C+AG+E N C +P
Sbjct: 262 GSCV-NHSVT--DDPPKMHCSAEGEWLVPIGKCMCKAGYE--EKNGTCQAPSP 309
Score = 42.7 bits (96), Expect = 0.045
Identities = 23/75 (30%), Positives = 41/75 (54%), Gaps = 7/75 (9%)
Query: 381 LTIAWNPPQVDLTDPDDTIESYEVKCFPKDSQDKNTNTTLRITKDPQVTITGLRKDTEYG 440
++++W P P+ I YE+K F KD + T+ T+ +K+ +T GL+ + Y
Sbjct: 323 ISLSWQEPD----RPNGIILEYEIKYFEKDQE---TSYTIIKSKETSITAEGLKPASVYV 375
Query: 441 IRVRAKMKRGWGEFS 455
++RA+ G+G FS
Sbjct: 376 FQIRARTAAGYGVFS 390
>UniRef50_Q4SQX3 Cluster: Chromosome 11 SCAF14528, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 11 SCAF14528, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 780
Score = 520 bits (1283), Expect = e-146
Identities = 249/386 (64%), Positives = 298/386 (77%), Gaps = 5/386 (1%)
Query: 553 SRTYIDPHTYEDPNQAVREFAREIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDV 612
+R YIDPHTYEDP QAV EFAREI+AS I IE IIG GEFG+VC G+++LP +I V
Sbjct: 387 ARFYIDPHTYEDPCQAVHEFAREIEASRIKIEKIIGSGEFGEVCYGRMRLPGK--RDIPV 444
Query: 613 AIKTLKPGSTERARRDFLAEASIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTF 672
A+KTLK G TE+ +RDFLAEASIM QF+HPNVI L+GVVT P+MIITE+MENGSLD+F
Sbjct: 445 ALKTLKVGYTEKQKRDFLAEASIMAQFDHPNVIRLEGVVTHSKPVMIITEYMENGSLDSF 504
Query: 673 LRANDGKFRVLQLVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSRE 732
LR +DG+F ++QLVG+LRGIA GM YLS++ YIHRDLAARN+LVNS LVCK++DFGLSR
Sbjct: 505 LRRHDGQFTIIQLVGLLRGIAAGMTYLSDLGYIHRDLAARNILVNSNLVCKVSDFGLSRV 564
Query: 733 IESTADGAYTTRGGKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSN 792
+E D AYTT GGKIP+RWTAPEAI FRKF+S+SDVWS G+V WEV S+GERPYWN +N
Sbjct: 565 LEDDPDAAYTTSGGKIPIRWTAPEAITFRKFSSSSDVWSYGVVMWEVTSYGERPYWNLTN 624
Query: 793 QDVIKSIEKGYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLIRCPDTLRK 852
+DVIKS+E+GYRLPAPM CP A++ LMLDCWQK+R RP F IV LDKLIR P+ L+
Sbjct: 625 RDVIKSVEEGYRLPAPMGCPAALHTLMLDCWQKDRNERPRFCQIVTVLDKLIRNPENLKS 684
Query: 853 IAQNRSAD--PLAGDT-PDLIQFTSVEEWLECIKMSRYIEKFRAAGISDMDAVVDLTVHQ 909
+ S D PL PDL SV EWL+ IKMSRY + F A G + V+ +
Sbjct: 685 MDTLCSLDSPPLMERAIPDLSSCNSVNEWLDTIKMSRYKDHFAAGGYHTLGHVLGMNQGD 744
Query: 910 LASLGVTLVGHQKKIMNSVQSMRAQI 935
+ LGVTL+GHQKKIM SVQ MRAQ+
Sbjct: 745 IQRLGVTLMGHQKKIMTSVQLMRAQV 770
Score = 105 bits (253), Expect = 4e-21
Identities = 77/280 (27%), Positives = 116/280 (41%), Gaps = 32/280 (11%)
Query: 210 CAPGKFKSHTGDEHCIPCPDHSESTIYAAAECKCTPKYYRAKKDPKTIPCTQPPSAPDNL 269
C G +K GD C CP HS S AA C C YYRA DP PC++PPS P N+
Sbjct: 2 CEVGFYKPVAGDGLCAKCPQHSHSETRAALSCPCDSSYYRAADDPPAAPCSRPPSCPLNV 61
Query: 270 TVTFADQFSISLTWQPPHNTGGRSDITYKISCANC----GP--TVEFRPGETGLNSTRVT 323
++ + S+ L W P +TGGRSD+ Y I C C GP + + PG T +
Sbjct: 62 -ISSVNGTSVHLEWDRPLDTGGRSDLQYSIMCQKCSGEGGPCESCDSHPGGTSAGRMGAS 120
Query: 324 I-SGLDPVTEYKFQVYAENGVSELSPDPANHIEITAVTEAXXXXXXXKLRILNTESDRLT 382
+ +G + E V + + V + NT + +T
Sbjct: 121 VAAGSGGMVERSGTVAIRFIPRQSGLTQPWVTVLNLVAHSNYSFRILATNAENTSQNSVT 180
Query: 383 IAWNPPQVDLTDPDDTIESYEVKCFPKDSQDKNTNTTLRI-------------------- 422
+ W+ P P+ I Y++K + K + +N + L +
Sbjct: 181 LQWHEPD----QPNGVILEYDIKYYEKRMKSQNVGSGLLMFEAVPSDLKDSEEHIYSTLK 236
Query: 423 TKDPQVTITGLRKDTEYGIRVRAKMKRGWGEFSGIVYART 462
+K+ + GL+ T+Y +VRA+ G G FS V +T
Sbjct: 237 SKNTTARVAGLKPGTKYIFQVRARTSAGCGRFSQNVEIQT 276
>UniRef50_UPI000069DB6A Cluster: Ephrin type-A receptor 6 precursor
(EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2)
(EPH homology kinase 2).; n=2; Xenopus tropicalis|Rep:
Ephrin type-A receptor 6 precursor (EC 2.7.10.1)
(Tyrosine-protein kinase receptor EHK-2) (EPH homology
kinase 2). - Xenopus tropicalis
Length = 952
Score = 519 bits (1280), Expect = e-145
Identities = 245/396 (61%), Positives = 300/396 (75%), Gaps = 4/396 (1%)
Query: 552 GSRTYIDPHTYEDPNQAVREFAREIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEID 611
G +TYIDP TYEDP+ AV EFA+EID S I IE +IG GEFG+VC G+LK PA EI
Sbjct: 559 GVKTYIDPDTYEDPSLAVHEFAKEIDPSRIRIERVIGAGEFGEVCSGRLKTPAK--KEIP 616
Query: 612 VAIKTLKPGSTERARRDFLAEASIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDT 671
VAIKTLK G +R R+DFL EASIMGQF+HPN+I L+GVVTK P+MI+ E+MENGSLD+
Sbjct: 617 VAIKTLKGGYVDRQRKDFLREASIMGQFDHPNIIRLEGVVTKSRPVMIVVEYMENGSLDS 676
Query: 672 FLRANDGKFRVLQLVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSR 731
FLR +DG+F V+QLVGMLRGIA+GM+YLS+M Y+HRDLAARN+LVNS LVCK++DFGLSR
Sbjct: 677 FLRKHDGQFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILVNSNLVCKVSDFGLSR 736
Query: 732 EIESTADGAYTTRGGKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWS 791
+E D AYTT GGKIP+RWTAPEAIAFRKF+SASD WS GIV WEVMS+GERPYW S
Sbjct: 737 VLEDDPDAAYTTTGGKIPIRWTAPEAIAFRKFSSASDAWSYGIVMWEVMSYGERPYWEMS 796
Query: 792 NQDVIKSIEKGYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLIRCPDTLR 851
NQDVI SIE+GYRLPAPM CP +++QLML CWQK+R RP FS IV LDKLIR P L
Sbjct: 797 NQDVILSIEEGYRLPAPMGCPVSLHQLMLHCWQKDRNIRPKFSDIVGFLDKLIRNPSALH 856
Query: 852 KIAQN--RSADPLAGDTPDLIQFTSVEEWLECIKMSRYIEKFRAAGISDMDAVVDLTVHQ 909
+ ++ GD P+ +V EWLE IKM +Y F A+G + +D V +T+
Sbjct: 857 ILVEDILGRMPESPGDAPEYHFVVTVSEWLESIKMGQYAHNFMASGFTTLDMVSRMTIDD 916
Query: 910 LASLGVTLVGHQKKIMNSVQSMRAQIRGSGPYGFLV 945
+ +G+TL+GHQ++I+ S+Q++R QI GF V
Sbjct: 917 IRRIGITLIGHQRRIVTSIQTLRLQIMHIQEKGFHV 952
Score = 249 bits (609), Expect = 3e-64
Identities = 140/420 (33%), Positives = 214/420 (50%), Gaps = 26/420 (6%)
Query: 48 SCKETFSLLYYEFDVATREQPPWEPESYKLVGRIAAGEG--RFNTNSEV-DINTEVKSIA 104
+CKETF+L Y E D A + ++P Y + IAA E + + + +NTEV+ +
Sbjct: 86 TCKETFNLHYMESDDAHAVK--FKPTQYSKIDTIAADESFTQMDLGDRILKLNTEVREVG 143
Query: 105 -VTKKGVYFAFRDQGACISILAVKVYYITCPDVNINFARFPATPTGREVTVIEQANGTCV 163
+TKKG Y AF+D GACI++++V+VYY CP + N A FP T + + + + G+C+
Sbjct: 144 PITKKGFYLAFQDIGACIALVSVRVYYKKCPYMVRNLAMFPDTIPRVDSSSLVEVRGSCI 203
Query: 164 ANAEVAPGEKAPVYLCKGDGKWTLPSGSCKCRAGFEPDHNNQICTECAPGKFKSHTGDEH 223
AE P C DG W +P G C C G+E + C C PG +KS G+
Sbjct: 204 KYAEE---RDTPKLYCGADGDWLVPLGRCVCSIGYEEVDGS--CHACRPGFYKSFAGNIK 258
Query: 224 CIPCPDHSESTIYAAAECKCTPKYYRAKKDPKTIPCTQPPSAPDNLTVTFADQFSISLTW 283
C CP HS + A C+C +YRA+KDP ++ CT+PPSAP N+ ++ ++ L W
Sbjct: 259 CSKCPPHSFTYAEATTVCQCEKGFYRAEKDPPSMACTKPPSAPRNVNFNM-NETALYLEW 317
Query: 284 QPPHNTGGRSDITYKISCANCGPT--------VEFRPGETGLNSTRVTISGLDPVTEYKF 335
PP +TGGR D+ Y + C C P+ + + P +GL + VT+ Y F
Sbjct: 318 SPPIDTGGRKDVVYNVLCKKCDPSQCELCGGGIRYVPAHSGLQNASVTVLDFLSHVNYTF 377
Query: 336 QVYAENGVSELSPDPANHIEITAVTEAXXXXXXXKLRILNTESDRLTIAWNPPQVDLTDP 395
+ A NGVSELS P + I T+ +R + + ++W P P
Sbjct: 378 DIEATNGVSELSFLPKPYTSIMITTDQEAPSLIGMVRKDWASQNSIALSWQEPDY----P 433
Query: 396 DDTIESYEVKCFPKDSQDKNTNTTLRITKDPQVTITGLRKDTEYGIRVRAKMKRGWGEFS 455
I YE+K + K+ + + ++T +K P V ITGL+ T+Y +R + G+ +S
Sbjct: 434 KGLIVDYEIKYYEKEHEQLSYSSTR--SKAPSVIITGLKPATKYIFHIRVRTTAGYSAYS 491
>UniRef50_Q4SFJ9 Cluster: Chromosome 7 SCAF14601, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 7 SCAF14601, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 761
Score = 504 bits (1243), Expect = e-141
Identities = 240/384 (62%), Positives = 300/384 (78%), Gaps = 8/384 (2%)
Query: 552 GSRTYIDPHTYEDPNQAVREFAREIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEID 611
G + YIDP TYEDPN+AVREFA+EID S + IE +IG GEFG+VCRG+LK+P E
Sbjct: 380 GVKVYIDPFTYEDPNEAVREFAKEIDVSFVKIEEVIGAGEFGEVCRGRLKIPGK--KENY 437
Query: 612 VAIKTLKPGSTERARRDFLAEASIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDT 671
VAIKTLK G T++ RRDFL+EASIMGQF+HPN+I L+GV+T P+MI+TEFMENG+LD+
Sbjct: 438 VAIKTLKGGYTDKQRRDFLSEASIMGQFQHPNIIHLEGVITASCPVMILTEFMENGALDS 497
Query: 672 FLRANDGKFRVLQLVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSR 731
FLR ND +F +QLVGMLRGIA+GM+YLSEM+Y+HRDLAARN+L+NS LVCK++DFGLSR
Sbjct: 498 FLRLNDSQFTPIQLVGMLRGIASGMKYLSEMSYVHRDLAARNILINSNLVCKVSDFGLSR 557
Query: 732 EI-ESTADGAYTTR-GGKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWN 789
+ E+++D YT+ GGKIP+RWTAPEAIAFRKFTSASDVWS GIV WEVMSFGERPYW+
Sbjct: 558 FLQENSSDPTYTSSLGGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVMSFGERPYWD 617
Query: 790 WSNQDVIKSIEKGYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLIRCPDT 849
SNQDVI +IE+ YRLP P DCP ++QLMLDCWQK+R+ RP F+ +V LDKLIR P +
Sbjct: 618 MSNQDVINAIEQDYRLPPPPDCPTHLHQLMLDCWQKDRSARPRFADLVSALDKLIRNPAS 677
Query: 850 LRKIAQNR--SADPLAGDTPDLI--QFTSVEEWLECIKMSRYIEKFRAAGISDMDAVVDL 905
L+ +AQ+R + PL L SV EWL IKM RY + F AG+S +D + +
Sbjct: 678 LKIVAQDRVGPSYPLLDQRAPLALSGCASVGEWLRTIKMERYEDSFLQAGLSTVDQLAQI 737
Query: 906 TVHQLASLGVTLVGHQKKIMNSVQ 929
+ L +GVTL GHQ+KI++S+Q
Sbjct: 738 STQDLLHMGVTLAGHQRKILSSIQ 761
Score = 96.3 bits (229), Expect = 3e-18
Identities = 69/206 (33%), Positives = 105/206 (50%), Gaps = 20/206 (9%)
Query: 262 PPSAPDNLTVTFADQFSISLTWQPPHNTGGRSDITYKISCA----------NCGPTVEFR 311
PPSAP ++ VT + ++ L W P +GGR+D++Y I C +CG +V R
Sbjct: 1 PPSAPRSI-VTQMNDSTLGLEWNRPLESGGRTDLSYSIRCTVCRAAGAPCLSCGDSVTHR 59
Query: 312 PGETGLNSTRVTISGLDPVTEYKFQVYAENGVSEL-SPDPAN-HIEITAVTEAXXXXXXX 369
P + GL RV + GL P Y F + A NGVS+L S +PA+ + IT +
Sbjct: 60 PTQYGLVERRVEVWGLLPQATYIFTIQALNGVSQLSSKEPASKSVNITTTHDVPSLVSLI 119
Query: 370 KLRILNTESDRLTIAWNPPQVDLTDPDDTIESYEVKCFPKDSQDKNTNTTLRITKDPQVT 429
+ RI +TES LT+ W+ P P TI Y+++ KD + ++ ++ Q
Sbjct: 120 Q-RIDSTESS-LTLHWSVPD----HPRYTILRYQIRYCEKDRRSEDQCHHTESNRN-QAV 172
Query: 430 ITGLRKDTEYGIRVRAKMKRGWGEFS 455
+T LR+ T Y ++VR G+G FS
Sbjct: 173 LTDLRRATPYEVQVRVHTAAGYGSFS 198
>UniRef50_Q4T272 Cluster: Chromosome undetermined SCAF10323, whole
genome shotgun sequence; n=1; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF10323,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 815
Score = 489 bits (1205), Expect = e-136
Identities = 237/385 (61%), Positives = 284/385 (73%), Gaps = 18/385 (4%)
Query: 551 TGSRTYIDPHTYEDPNQAVREFAREIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEI 610
TG RTY+DP TYEDPNQAV +FA+EI S I+IE IIG GEFG+VC G L+LP EI
Sbjct: 448 TGLRTYVDPLTYEDPNQAVHQFAQEIHLSSISIERIIGAGEFGEVCSGPLRLPGK--REI 505
Query: 611 DVAIKTLKPGSTERARRDFLAEASIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLD 670
VAIKTLK G TE+ RRDFL EASIMGQF HPN+I L+GVVTK P+MIITE+MENGSLD
Sbjct: 506 LVAIKTLKAGYTEQQRRDFLWEASIMGQFNHPNIIRLEGVVTKSKPVMIITEYMENGSLD 565
Query: 671 TFLRANDGKFRVLQLVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLS 730
TFL+ NDG+F V+QLVGMLRGIA+GM+YLS+M Y+HRDLAARN+LV+ LVCK++DFGLS
Sbjct: 566 TFLKKNDGQFTVIQLVGMLRGIASGMRYLSDMGYVHRDLAARNILVDGHLVCKVSDFGLS 625
Query: 731 REIESTADGAYTTRGGKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNW 790
R +E + AYTT+GGKIP+RWTAPEAIA+RKFTSASDVWS G+V WEVMS+GERPYW+
Sbjct: 626 RALEDDPEAAYTTQGGKIPIRWTAPEAIAYRKFTSASDVWSYGVVMWEVMSYGERPYWDM 685
Query: 791 SNQDVIKSIEKGYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLIRCPDTL 850
SNQDVIK++E+ YRLP PMDCPE++YQLM DCWQ+ERT P S++ CP
Sbjct: 686 SNQDVIKAVEENYRLPGPMDCPESLYQLMTDCWQRERT-SPAQVSVLWP-----ECPTCW 739
Query: 851 RKIAQNRSADPLAGDTPDLIQFTSVEEWLECIKMSRYIEKFRAAGISDMDAVVDLTVHQL 910
N + +V EWL+ IKM RY E F G S +D V +T L
Sbjct: 740 WNTLVNAGGG----------RRQTVAEWLDSIKMGRYTELFLEGGYSSLDTVAHMTSEDL 789
Query: 911 ASLGVTLVGHQKKIMNSVQSMRAQI 935
+GV L GHQKKI +S+Q MR +
Sbjct: 790 RRVGVNLAGHQKKIFSSIQEMRVHL 814
Score = 138 bits (333), Expect = 9e-31
Identities = 82/246 (33%), Positives = 122/246 (49%), Gaps = 19/246 (7%)
Query: 210 CAPGKFKSHTGDEHCIPCPDHSESTIYAAAECKCTPKYYRAKKDPKTIPCTQPPSAPDNL 269
C G ++S C CP HS S A C C P YYR + D ++ CT+PPSAP N
Sbjct: 46 CRVGFYRSLLESPSCSRCPPHSVSRQPGALSCPCEPSYYRTQADAPSMACTRPPSAPHN- 104
Query: 270 TVTFADQFSISLTWQPPHNTGGRSDITYKISC----------ANCGPTVEFRPGETGLNS 319
++ ++ S+ L W P TGGR D+ Y + C CGP+V F PG GL +
Sbjct: 105 AMSNVNETSVFLEWSVPVETGGRKDLRYNVLCRQALPEGRGLEECGPSVRFLPGRVGLTN 164
Query: 320 TRVTISGLDPVTEYKFQVYAENGVSELSPDPA-NHIEITAVTEAXXXXXXXKLRILNTES 378
T V ++ L T Y F + A NGVSEL+ A +H+ + T +R +T
Sbjct: 165 TSVMVADLQSHTNYSFLLEAVNGVSELADAHAQHHVTLNVTTNQAAPSAVSVVRKGHTGK 224
Query: 379 DRLTIAWNPPQVDLTDPDDTIESYEVKCFPKDSQDKNTNTTLRITKDPQVTITGLRKDTE 438
+ ++W P P+ I YE+K F K+ QD ++ T +R +K+ Q+ + L+ +
Sbjct: 225 SSMALSWAEPD----RPNGVILEYEIKYFEKE-QD-SSYTIIR-SKELQMVVEDLKPSSL 277
Query: 439 YGIRVR 444
Y +VR
Sbjct: 278 YVFQVR 283
>UniRef50_Q4SC90 Cluster: Chromosome undetermined SCAF14659, whole
genome shotgun sequence; n=3; Tetraodontidae|Rep:
Chromosome undetermined SCAF14659, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 712
Score = 482 bits (1189), Expect = e-134
Identities = 239/413 (57%), Positives = 294/413 (71%), Gaps = 11/413 (2%)
Query: 525 RNGEVYTGPDRPAKTSSNATTPLFAGTGSRTYIDPHTYEDPNQAVREFAREIDASCITIE 584
RN + GP+ +SS PL +TY+DPHTYEDPN AV +FA EI S I E
Sbjct: 302 RNPHIRQGPEDTYFSSSEQLKPL------KTYVDPHTYEDPNTAVMKFATEIHPSHIAKE 355
Query: 585 AIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEASIMGQFEHPNV 644
+IG GEFG+V RG LK+P E VAIKTLKPG TE+ R+DFL+EASIMGQF H N+
Sbjct: 356 KVIGAGEFGEVYRGILKVPGR--KESAVAIKTLKPGYTEKQRQDFLSEASIMGQFAHQNI 413
Query: 645 IFLQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFRVLQLVGMLRGIATGMQYLSEMNY 704
I L+GVVTK MIITE+MENG+LD +LR +DG+F QLVGMLRGIA GM+YLS+M+Y
Sbjct: 414 IRLEGVVTKFKHAMIITEYMENGALDRYLRDHDGEFTSFQLVGMLRGIAAGMKYLSDMSY 473
Query: 705 IHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGGKIPVRWTAPEAIAFRKFT 764
+HRDLAARN+LVN+ L CK++DFGLSR +E +G YTT GGKIP+RWTAPEAIA+RKF
Sbjct: 474 VHRDLAARNILVNNTLECKVSDFGLSRVLEDDPEGTYTTSGGKIPIRWTAPEAIAYRKFA 533
Query: 765 SASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEAVYQLMLDCWQ 824
SASDVWS GIV WEVM+FGERPYW+ SN +V+K+I + +RLPAPMDCP AVYQLML CW
Sbjct: 534 SASDVWSFGIVMWEVMAFGERPYWDMSNHEVMKAINEAFRLPAPMDCPSAVYQLMLQCWL 593
Query: 825 KERTHRPTFSSIVKTLDKLIRCPDTLRKIA--QNRSADPLAGDT-PDLIQFTSVEEWLEC 881
+R RP F IV LDKL+R PD+L+ IA R + L + D F SV EWLE
Sbjct: 594 HDRAKRPRFGDIVNLLDKLLRSPDSLKTIADFDPRVSIRLPSTSGSDGSPFRSVSEWLES 653
Query: 882 IKMSRYIEKFRAAGISDMDAVVDLTVHQLASLGVTLVGHQKKIMNSVQSMRAQ 934
IKMS+Y E F AG+ MD V+ + + ++GV L GH K+I S+ ++ Q
Sbjct: 654 IKMSQYSENFSRAGVVTMDQVLQMKNEDIKNIGVRLPGHLKRIAYSILGLKDQ 706
Score = 118 bits (285), Expect = 6e-25
Identities = 81/249 (32%), Positives = 116/249 (46%), Gaps = 20/249 (8%)
Query: 213 GKFKSHTGDEHCIPCPDHSESTIYAAAECKCTPKYYRAKKDPKTIPCTQPPSAPDNLTVT 272
G FK E C PCP +++ A C C +YRA DP T PC+ PSAP +L T
Sbjct: 2 GFFKGEASGEKCKPCPANTQRLNSGALFCPCMDGFYRAPTDPLTGPCSGLPSAPRDLKAT 61
Query: 273 FADQFSISLTWQPPHNTGGRSDITYKIS--------CANCGPTVEFRPGETGLNSTRVTI 324
+ + L+W PP +TGGR+DITYKI C +CG + + P GL T+V +
Sbjct: 62 -TNAGKLHLSWSPPADTGGRTDITYKIECQRCEGTVCQSCGEKIHYEPASVGLTDTKVLV 120
Query: 325 SGLDPVTEYKFQVYAENGVS---ELSPDPANH-IEITAVTEAXXXXXXXK---LRILNTE 377
S LD Y F V A++G+S +P + +A+T + K +R++
Sbjct: 121 SDLDAHLNYTFTVEAQSGISLFISQAPQQVKRPVSTSALTTSLLYTDPPKITTMRLVAKT 180
Query: 378 SDRLTIAWN-PPQVDLTDPDDTIESYEVKCFPKDSQDKNTNTTLRITKDPQVTITGLRKD 436
S L+++W+ P+ P YE+ KD T T+ I + V I L
Sbjct: 181 STSLSLSWDVSPRPRAHSPP---IRYELTYRKKDDNLDVTTYTVLILEKNSVQIFELAPG 237
Query: 437 TEYGIRVRA 445
T Y RV A
Sbjct: 238 TAYLFRVLA 246
>UniRef50_Q4RXA0 Cluster: Chromosome 11 SCAF14979, whole genome
shotgun sequence; n=5; Euteleostomi|Rep: Chromosome 11
SCAF14979, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 1042
Score = 479 bits (1181), Expect = e-133
Identities = 226/382 (59%), Positives = 288/382 (75%), Gaps = 5/382 (1%)
Query: 554 RTYIDPHTYEDPNQAVREFAREIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVA 613
++Y+DPH YEDPN A+++F EID S I+ + +IG GEFG+V RG +K E++VA
Sbjct: 655 KSYVDPHMYEDPNIAIQKFVTEIDPSAISKQKVIGVGEFGEVFRGVMKTRGQ--GEVNVA 712
Query: 614 IKTLKPGSTERARRDFLAEASIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFL 673
IKTLKPG +E+ R DFL+EASIMGQF HPN+I L+GVVTK IMI+TE+M+NG+LDT+L
Sbjct: 713 IKTLKPGYSEKQRLDFLSEASIMGQFSHPNIIHLEGVVTKFKHIMIVTEYMDNGALDTYL 772
Query: 674 RANDGKFRVLQLVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREI 733
+ DG+ QLVGMLRGIA GMQYLS M+Y+HRDLAARN+LVNS L CK++DFGLSR +
Sbjct: 773 KGRDGEIPPYQLVGMLRGIAAGMQYLSNMSYVHRDLAARNILVNSNLECKVSDFGLSRVL 832
Query: 734 ESTADGAYTTRGGKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQ 793
E +G YTTRGGKIP+RWTAPEAIA+RKFTSASDVWS GIV WEVM+FGERPYW+ SN
Sbjct: 833 EDDDEGTYTTRGGKIPIRWTAPEAIAYRKFTSASDVWSFGIVMWEVMAFGERPYWDMSNH 892
Query: 794 DVIKSIEKGYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLIRCPDTLRKI 853
+V+K+I + +RLPAPMDCP A+YQLML CWQ +R+ RP FS IV LDKL+R P++L+ I
Sbjct: 893 EVMKAINEAFRLPAPMDCPSAIYQLMLQCWQHDRSKRPRFSDIVSFLDKLLRSPESLKTI 952
Query: 854 A--QNRSADPLAGDTP-DLIQFTSVEEWLECIKMSRYIEKFRAAGISDMDAVVDLTVHQL 910
A R + L + D F SV EWLE I+MS+Y E F AGI+ M+ V+ L +
Sbjct: 953 ADFDPRVSIRLPSTSGCDGTLFRSVPEWLESIRMSQYSESFARAGITSMEQVLALRHEDI 1012
Query: 911 ASLGVTLVGHQKKIMNSVQSMR 932
++GV L GH K+I S+ ++
Sbjct: 1013 KNIGVRLPGHMKRIAYSILGLK 1034
Score = 188 bits (458), Expect = 6e-46
Identities = 111/342 (32%), Positives = 169/342 (49%), Gaps = 25/342 (7%)
Query: 43 NGNALSCKETFSLLYYEFDVATREQPPWEPESYKLVGRIAAGEGRFNTNSEVDINTEVKS 102
+G +++CKETF+L E D + ++ V IA E + +NTE ++
Sbjct: 79 DGASVACKETFNLYISEADADVGTN--FRKGQFRKVATIAPDE--VTHGRVLKVNTETRT 134
Query: 103 IA-VTKKGVYFAFRDQGACISILAVKVYYITCPDVNINFARFPATPTGREVTVIEQANGT 161
+ ++++G Y +F+D GAC+++L+ +VYY TCP + A FP T +++ G
Sbjct: 135 VGPLSRRGFYLSFQDMGACVALLSTRVYYKTCPSTVQSLAEFPET----VADALKEVEGA 190
Query: 162 CVANAEVAPGEKAPVYLCKGDGKWTLPSGSCKCRAGFEPDHNNQICTECAPGKFKSHTGD 221
CV NA A P C DG+W +P G C+C AG+E ++ C C PG FK+
Sbjct: 191 CVENAISA---TTPRIYCSADGEWVVPVGQCQCLAGYESTGDS--CQACKPGYFKASAES 245
Query: 222 EHCIPCPDHSESTIYAAAECKCTPKYYRAKKDPKTIPCTQPPSAPDNLTVT-FADQFSIS 280
+ C CPD++ + A +C+C P P PPSAP +L+ + + + +
Sbjct: 246 KFCQVCPDNTRPSEAGATQCQCEEGPGDVHCGP--CPPPAPPSAPRDLSSSALSAEGRLQ 303
Query: 281 LTWQPPHNTGGRSDITYKISCAN--------CGPTVEFRPGETGLNSTRVTISGLDPVTE 332
L+W PP TGGR D+TY ++CA+ CG + F PG L TRV ++ LD
Sbjct: 304 LSWSPPLVTGGRRDLTYSVACAHCSEGQCVPCGEKIRFEPGPADLQETRVVVTDLDAHLN 363
Query: 333 YKFQVYAENGVSELSPDPANHIEITAVTEAXXXXXXXKLRIL 374
Y F V A +GVS+ S A TA+ LR L
Sbjct: 364 YTFTVEAHSGVSQFSSGKAVASITTALDHTGELGPTPALRFL 405
>UniRef50_A2CG59 Cluster: Eph receptor B1; n=23; Euteleostomi|Rep:
Eph receptor B1 - Mus musculus (Mouse)
Length = 943
Score = 477 bits (1176), Expect = e-133
Identities = 229/356 (64%), Positives = 279/356 (78%), Gaps = 7/356 (1%)
Query: 588 GGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEASIMGQFEHPNVIFL 647
G GEFG+V +G+LKLP EI VAIKTLK G +E+ RRDFL+EASIMGQF+HPN+I L
Sbjct: 585 GRGEFGEVYKGRLKLPGK--REIYVAIKTLKAGYSEKQRRDFLSEASIMGQFDHPNIIRL 642
Query: 648 QGVVTKCNPIMIITEFMENGSLDTFLRANDGKFRVLQLVGMLRGIATGMQYLSEMNYIHR 707
+GVVTK P+MIITEFMENG+LD+FLR NDG+F V+QLVGMLRGIA GM+YLSEMNY+HR
Sbjct: 643 EGVVTKSRPVMIITEFMENGALDSFLRQNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHR 702
Query: 708 DLAARNVLVNSQLVCKIADFGLSREI-ESTADGAYTTR-GGKIPVRWTAPEAIAFRKFTS 765
DLAARN+LVNS LVCK++DFGLSR + + T+D YT+ GGKIPVRWTAPEAIA+RKFTS
Sbjct: 703 DLAARNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTSSLGGKIPVRWTAPEAIAYRKFTS 762
Query: 766 ASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEAVYQLMLDCWQK 825
ASDVWS GIV WEVMSFGERPYW+ SNQDVI +IE+ YRLP PMDCP A++QLMLDCWQK
Sbjct: 763 ASDVWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYRLPPPMDCPAALHQLMLDCWQK 822
Query: 826 ERTHRPTFSSIVKTLDKLIRCPDTLRKIAQNRS--ADPLAG-DTPDLIQFTSVEEWLECI 882
+R RP F+ IV TLDK+IR P +L+ +A + + PL PD FT+V++WL I
Sbjct: 823 DRNSRPRFAEIVNTLDKMIRNPASLKTVATITAVPSQPLLDRSIPDFTAFTTVDDWLSAI 882
Query: 883 KMSRYIEKFRAAGISDMDAVVDLTVHQLASLGVTLVGHQKKIMNSVQSMRAQIRGS 938
KM +Y + F AG + + V +T L +GVTL GHQKKI++S+ SMR Q+ S
Sbjct: 883 KMVQYRDSFLTAGFTSLQLVTQMTSEDLLRIGVTLAGHQKKILSSIHSMRVQMNQS 938
Score = 291 bits (714), Expect = 6e-77
Identities = 162/426 (38%), Positives = 226/426 (53%), Gaps = 28/426 (6%)
Query: 48 SCKETFSLLYYEFD--VATREQPPWEPESYKLVGRIAAGEGRFNTNSE---VDINTEVKS 102
SCKETF+L YYE D +AT++ W Y V IAA E + + +NTEV+S
Sbjct: 105 SCKETFNLYYYETDSVIATKKSAFWSEAPYLKVDTIAADESFSQVDFGGRLMKVNTEVRS 164
Query: 103 IA-VTKKGVYFAFRDQGACISILAVKVYYITCPDVNINFARFPATPTGREVTVIEQANGT 161
+T+ G Y AF+D GAC+S+L+V+V++ CP + NFA FP T TG E T + A GT
Sbjct: 165 FGPLTRNGFYLAFQDYGACMSLLSVRVFFKKCPSIVQNFAVFPETMTGAESTSLVIARGT 224
Query: 162 CVANAEVAPGEKAPVYL-CKGDGKWTLPSGSCKCRAGFEPDHNNQICTECAPGKFKSHTG 220
C+ NAE P+ L C GDG+W +P G C C+ G+EP+ N+ C C G FK+
Sbjct: 225 CIPNAEEV---DVPIKLYCNGDGEWMVPIGRCTCKPGYEPE-NSVACKACPAGTFKASQE 280
Query: 221 DEHCIPCPDHSESTIYAAAECKCTPKYYRAKKDPKTIPCTQPPSAPDNLTVTFADQFSIS 280
E C CP +S S A+ C C YYRA DP + CT PS P N+ ++ ++ SI
Sbjct: 281 AEGCSHCPSNSRSPSEASPICTCRTGYYRADFDPPEVACTSVPSGPRNV-ISIVNETSII 339
Query: 281 LTWQPPHNTGGRSDITYKI----------SCANCGPTVEFRPGETGLNSTRVTISGLDPV 330
L W PP TGGR D+TY I SC+ C VEF P + GL RV+IS L
Sbjct: 340 LEWHPPRETGGRDDVTYNIICKKCRADRRSCSRCDDNVEFVPRQLGLTECRVSISSLWAH 399
Query: 331 TEYKFQVYAENGVSELSPDPANHIEITAVTEAXXXXXXXKLRILNTESDRLTIAWNPPQV 390
T Y F + A NGVS SP P H+ + T + ++ +T++W P+
Sbjct: 400 TPYTFDIQAINGVSSKSPFPPQHVSVNITTNQAAPSTVPIMHQVSATMRSITLSWPQPE- 458
Query: 391 DLTDPDDTIESYEVKCFPKDSQDKNTNTTLRITKDPQVTITGLRKDTEYGIRVRAKMKRG 450
P+ I YE++ + K+ + N++ T + I GLR Y ++VRA+ G
Sbjct: 459 ---QPNGIILDYEIRYYEKEHNEFNSSMARSQTNTAR--IDGLRPGMVYVVQVRARTVAG 513
Query: 451 WGEFSG 456
+G+FSG
Sbjct: 514 YGKFSG 519
>UniRef50_Q4RV12 Cluster: Ephrin receptor; n=2; Tetraodontidae|Rep:
Ephrin receptor - Tetraodon nigroviridis (Green puffer)
Length = 1006
Score = 469 bits (1156), Expect = e-130
Identities = 227/393 (57%), Positives = 294/393 (74%), Gaps = 23/393 (5%)
Query: 537 AKTSSNATTPLFAGTGSRTYIDPHTYEDPNQAVREFAREIDASCITIEAIIGGGEFGDVC 596
+KT ++ G + Y+DP TYEDP+QA+ EFA+EID S I IE +IG GEFG+VC
Sbjct: 617 SKTKQDSEEEKHLNPGVKIYVDPFTYEDPDQAIHEFAKEIDVSSIHIERVIGMGEFGEVC 676
Query: 597 RGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEASIMGQFEHPNVIFLQGVVTKCNP 656
G+L++ EI VAIK+LK G +++ RRDFL+EASIMGQF+HPN+I L+GVVT+C P
Sbjct: 677 SGRLRVQGK--REIYVAIKSLKAGYSDKQRRDFLSEASIMGQFDHPNIIRLEGVVTRCKP 734
Query: 657 IMIITEFMENGSLDTFLRANDGKFRVLQLVGMLRGIATGMQYLSEMNYIHRDLAARNVLV 716
+MIITE+MENGSLD FLR +DG+F V+QLVGMLRGIA+GM+YLS+M+Y+HRDLAARN+LV
Sbjct: 735 LMIITEYMENGSLDAFLRKHDGQFTVIQLVGMLRGIASGMKYLSDMSYVHRDLAARNILV 794
Query: 717 NSQLVCKIADFGLSREIESTADGAYTTR---------GGKIPVRWTAPEAIAFRKFTSAS 767
NS LVCK++DFGLSR +E + AYTTR GGKIP+RWTAPEAIA+RKFT+AS
Sbjct: 795 NSNLVCKVSDFGLSRVLEDDPEAAYTTRENTGTYLSPGGKIPIRWTAPEAIAYRKFTTAS 854
Query: 768 DVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEAVYQLMLDCWQKER 827
DVWS GIV WEV+S+GERPYW+ +NQDVIK+IE+GYRLPAPMDCP ++QLMLDCW++ER
Sbjct: 855 DVWSYGIVMWEVVSYGERPYWDMNNQDVIKAIEEGYRLPAPMDCPLVLHQLMLDCWERER 914
Query: 828 THRPTFSSIVKTLDKLIRCPDTLRKIAQNR----------SADPLAGDTPDL-IQFTSVE 876
RPTFS I+ LDKLIR P TLR+ +R ++ P++ + SV
Sbjct: 915 AERPTFSQILNMLDKLIRNPGTLRRTGGDRPTGTVLETGVGSEVCVSVVPEVCLSEWSVC 974
Query: 877 EWLECIKMSRYIEKFRAAGISDMDAVVDLTVHQ 909
WL+ + + RY + AAG + M++++ LT HQ
Sbjct: 975 LWLQSVGLDRYRDTLAAAGYTSMESLLTLT-HQ 1006
Score = 190 bits (462), Expect = 2e-46
Identities = 98/261 (37%), Positives = 146/261 (55%), Gaps = 12/261 (4%)
Query: 48 SCKETFSLLYYEFDVATREQPPWEPESYKLVGRIAAGEG--RFNTNSEV-DINTEVKSIA 104
+CKETF+L Y+E + RE E S+ V +AA E + + + +NTEV+ +
Sbjct: 95 TCKETFNLYYHESN-EERESYIRE-SSFIKVDTVAADESFTQVDVGDRIMKLNTEVRDVR 152
Query: 105 VT-KKGVYFAFRDQGACISILAVKVYYITCPDVNINFARFPATPTGREVTVIEQANGTCV 163
VT +KG Y AF+D GACI++++V+V+Y TCP N A FP T TG + + + + G+CV
Sbjct: 153 VTTRKGFYLAFQDVGACIALVSVRVFYKTCPLTIRNLATFPDTITGADTSSLVEVRGSCV 212
Query: 164 ANAEVAPGEKAPVYLCKGDGKWTLPSGSCKCRAGFEPDHNNQICTECAPGKFKSHTGDEH 223
+E + P C DG+W +P G C C G++ + C C+ G +K+ + D
Sbjct: 213 NQSE---EREEPKMYCGADGEWLVPIGGCLCNPGYQ--EKSGACQACSAGFYKARSSDAA 267
Query: 224 CIPCPDHSESTIYAAAECKCTPKYYRAKKDPKTIPCTQPPSAPDNLTVTFADQFSISLTW 283
C CP HS + A C C ++RA DP ++ CTQPPSAP L ++ ++ S+ L W
Sbjct: 268 CSKCPPHSYALRDRATVCDCHSGFFRADSDPPSMACTQPPSAPQQL-ISAVNETSVVLEW 326
Query: 284 QPPHNTGGRSDITYKISCANC 304
PP GGRSD +Y + C C
Sbjct: 327 APPRRLGGRSDTSYSLECLIC 347
Score = 87.0 bits (206), Expect = 2e-15
Identities = 57/181 (31%), Positives = 82/181 (45%), Gaps = 7/181 (3%)
Query: 285 PPHNTGGRSDITYKISCANCGPTVEFRPGETGLNSTRVTISGLDPVTEYKFQVYAENGVS 344
PP G S + C CG V F P +TGL +T+V +S L T Y F V+A NGVS
Sbjct: 400 PPGEDPGLSPDSASQLCLPCGADVLFSPSQTGLKTTKVVVSELRAHTHYTFIVHARNGVS 459
Query: 345 ELSPDPANH-IEITAVTEAXXXXXXXKLRILNTESDRLTIAWNPPQVDLTDPDDTIESYE 403
+ A+ +T T +++ + L++AW P P+ I YE
Sbjct: 460 QAGGVGASQSASVTVTTNQAAPSPVSSIQVTDVTRHSLSLAWQQPD----RPNGVILEYE 515
Query: 404 VKCFPKDSQDKNTNTTLRITKDPQVTITGLRKDTEYGIRVRAKMKRGWGEFSGIVYARTN 463
VK + KD +++ ++ V TGL T Y VRA+ G+G+FS TN
Sbjct: 516 VKFYEKDQKERAYRIMRTFSRGADV--TGLSPLTVYVFHVRARTAAGYGDFSTPFEFSTN 573
Query: 464 S 464
S
Sbjct: 574 S 574
>UniRef50_Q4H3M4 Cluster: Ephrin receptor; n=2; Ciona
intestinalis|Rep: Ephrin receptor - Ciona intestinalis
(Transparent sea squirt)
Length = 1048
Score = 454 bits (1119), Expect = e-126
Identities = 207/303 (68%), Positives = 252/303 (83%), Gaps = 1/303 (0%)
Query: 552 GSRTYIDPHTYEDPNQAVREFAREIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEID 611
G +TYIDP TYEDP +AV +F +EIDAS I IE +IGGGEFG+VC G+++LP S E D
Sbjct: 614 GHKTYIDPTTYEDPARAVLDFTKEIDASYIGIEEVIGGGEFGEVCLGRMRLPNS-KKEHD 672
Query: 612 VAIKTLKPGSTERARRDFLAEASIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDT 671
VAIKTLK G + + + DFL EASIMGQF+HPNVI L+GVVTK P MIITE+MENGSLDT
Sbjct: 673 VAIKTLKAGYSTQQKLDFLGEASIMGQFDHPNVIRLEGVVTKSQPHMIITEYMENGSLDT 732
Query: 672 FLRANDGKFRVLQLVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSR 731
FLR +DG+F V+QLVG+LR IA GM+YLS+M Y+HRDLAARN+LVN+QL+CK++DFGLSR
Sbjct: 733 FLRKHDGEFTVIQLVGILRNIAAGMKYLSDMGYVHRDLAARNILVNAQLICKVSDFGLSR 792
Query: 732 EIESTADGAYTTRGGKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWS 791
+E ++D YTTRGGKIP+RWTAPEAI +RKFTSASDVWS GIV WEVMS+GERPYW S
Sbjct: 793 VLEESSDSTYTTRGGKIPIRWTAPEAINYRKFTSASDVWSYGIVMWEVMSYGERPYWGMS 852
Query: 792 NQDVIKSIEKGYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLIRCPDTLR 851
NQDVI ++ GYRLPAPMDCP+ ++LMLDCW+K+R RP FS +V TLD++IR P+ L+
Sbjct: 853 NQDVIHAVGTGYRLPAPMDCPQVQHELMLDCWKKDRNERPKFSQVVATLDRMIREPEQLK 912
Query: 852 KIA 854
IA
Sbjct: 913 VIA 915
Score = 272 bits (667), Expect = 3e-71
Identities = 150/427 (35%), Positives = 217/427 (50%), Gaps = 24/427 (5%)
Query: 45 NALSCKETFSLLYYEFD--VATREQPPWEPESYKLVGRIAAGEGRFNTNSEVDINTEVKS 102
N +CKETF+L YYE D AT PPW +Y V IAA + RF S + N E +
Sbjct: 115 NVATCKETFNLYYYETDRDEATSTFPPWREGAYIKVDTIAADK-RFKPGS-AERNFETRD 172
Query: 103 IA-VTKKGVYFAFRDQGACISILAVKVYYITCPDVNINFARFPATPTGREVTVIEQANGT 161
I +TK+GVY A +D GAC++++ V+VYY C N A F T G + + +ANGT
Sbjct: 173 IGPLTKRGVYLAIQDTGACMALMHVRVYYKYCAPTESNLANFGRTTAGPYMASLVEANGT 232
Query: 162 CVANAEVAPGEKAPVYLCKGDGKWTLPSGSCKCRAGFEPDHNNQICTECAPGKFKSHTGD 221
CV N+ +A + + C +G+W +P GSC C G+ PD+ + C EC G +KS G+
Sbjct: 233 CVDNS-LADNDDRATFRCNSEGEWIVPKGSCLCDRGYGPDYTSTSCQECGRGFYKSSVGN 291
Query: 222 EHCIPCPDHSESTIYAAAECKCTPKYYRAKKDPKTIPCTQPPSAPDNLTVTFADQFSISL 281
C+ CP +SES + EC+C P YYRA D PC+QPPS P N+ + +Q I+L
Sbjct: 292 GGCVRCPAYSESQSDGSTECQCMPGYYRALSDDAAKPCSQPPSKPVNV-LAIVNQTKITL 350
Query: 282 TWQPPHNTGGRSDITYKIS----------CANCGPTVEFRPGETGLNSTRVTISGLDPVT 331
TW+ P N GGR DITY+I CA C V+F P + L T+V + L
Sbjct: 351 TWERPFNDGGRDDITYRIECQRCQVGFDHCAPCPQGVDFEPRQRDLVVTKVVVRDLSSYA 410
Query: 332 EYKFQVYAENG---VSELSPDPANHIEITAVTEAXXXXXXXKLRILNTESDRLTIAWNPP 388
Y+F+++A NG V++LSP + E+T T +R+ + + W+ P
Sbjct: 411 YYRFKIFAINGVTWVAQLSPSEVEYAEVTVETNEAAPSMVLGVRVTDLSETSAILTWDTP 470
Query: 389 QVDLTDPDDTIESYEVKCFPKDSQDKNTNTTLRITKDPQVTITGLRKDTEYGIRVRAKMK 448
+ I SY V T + + GL+++ Y ++VRA
Sbjct: 471 ----AKVNGLIRSYVVSLGLVYQGQVTDMRMFNSTSKRSMRLDGLKQNNMYAVKVRASTD 526
Query: 449 RGWGEFS 455
G+G +S
Sbjct: 527 AGFGPYS 533
Score = 47.2 bits (107), Expect = 0.002
Identities = 21/60 (35%), Positives = 35/60 (58%)
Query: 873 TSVEEWLECIKMSRYIEKFRAAGISDMDAVVDLTVHQLASLGVTLVGHQKKIMNSVQSMR 932
+S+ WL+ + + Y E F +AG S +D V+ ++ LASLG+ Q +M S+ S+R
Sbjct: 967 SSLGVWLDGLGLGNYKENFVSAGYSSLDQVLQMSPSDLASLGIVETNQQNAVMESISSIR 1026
>UniRef50_Q4SP88 Cluster: Ephrin receptor; n=2; Tetraodon
nigroviridis|Rep: Ephrin receptor - Tetraodon
nigroviridis (Green puffer)
Length = 950
Score = 451 bits (1112), Expect = e-125
Identities = 211/317 (66%), Positives = 255/317 (80%), Gaps = 4/317 (1%)
Query: 548 FAGTGSRTYIDPHTYEDPNQAVREFAREIDASCITIEAIIGGGEFGDVCRGKLKLPASCG 607
+ G + YIDP TYEDPN AV EFA+EID SC+ IE +IG GEFG+VCRG+LK
Sbjct: 603 YISPGVKVYIDPFTYEDPNDAVHEFAKEIDISCVKIEEVIGAGEFGEVCRGRLKQAGR-- 660
Query: 608 PEIDVAIKTLKPGSTERARRDFLAEASIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENG 667
E+ VAIKTLK G TER RRDFLAEASIMGQF+HPNVI L+GV+T+ P++IITEFMENG
Sbjct: 661 REMVVAIKTLKAGYTERQRRDFLAEASIMGQFDHPNVIRLEGVLTRSCPVLIITEFMENG 720
Query: 668 SLDTFLRANDGKFRVLQLVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADF 727
+LD+FLR NDG+F + QLVGMLRG+A GM+YLS+MNY+HRDLAARN+LVNS LVCK++DF
Sbjct: 721 ALDSFLRLNDGRFTMTQLVGMLRGVAAGMKYLSDMNYVHRDLAARNILVNSNLVCKVSDF 780
Query: 728 GLSREIEST-ADGAYTTR-GGKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGER 785
GLSR ++ T AD YT+ GGKIP+RWTAPEAIAFRKFT+ASDVWS GIV WEV+S+GER
Sbjct: 781 GLSRFLDDTSADPTYTSSLGGKIPIRWTAPEAIAFRKFTTASDVWSYGIVMWEVVSYGER 840
Query: 786 PYWNWSNQDVIKSIEKGYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLIR 845
PYW+ SNQDV+ ++E+ YRLP PMDCP ++QLML+CW KER RP FS IV TLDKL+R
Sbjct: 841 PYWDMSNQDVMTAVEQDYRLPPPMDCPMVLHQLMLECWMKERNLRPKFSRIVGTLDKLLR 900
Query: 846 CPDTLRKIAQNRSADPL 862
L+ + + S D L
Sbjct: 901 NAACLKMVTSSYSGDLL 917
Score = 252 bits (618), Expect = 3e-65
Identities = 154/440 (35%), Positives = 219/440 (49%), Gaps = 45/440 (10%)
Query: 48 SCKETFSLLYYEFD--VATREQPPWEPESYKLVGRIAAGEGRFNTNSEVDINTEVKSIA- 104
SCKETF+L YYE D AT P W Y V IA E F+ INT+V+S
Sbjct: 86 SCKETFNLFYYESDGDTATDASPQWRENPYVKVDTIAPDES-FSLLEAGRINTKVRSFGP 144
Query: 105 VTKKGVYFAFRDQGACISILAVKVYYITCPDVNINFARFPATPTGREVTVIEQANGTCVA 164
++K G Y AF+D GAC+S+++V+V++ C NFA FP T TG E T + A G CV+
Sbjct: 145 LSKAGFYLAFQDLGACMSLISVRVFFKKCSTTIANFAVFPETATGAEATSLVIAPGACVS 204
Query: 165 NA-EVAPGEKAPVYLCKGDGKWTLPSGSCKCRAGFEPDHNNQICTECAPGKFKSHTGDEH 223
NA EV+ K +Y C GDG+W +P GSC C +G+EP +N C C PG FK GD
Sbjct: 205 NAMEVSVPLK--LY-CNGDGEWMVPVGSCTCVSGYEPSPDNTQCQACFPGTFKPKLGDGS 261
Query: 224 CIPCPDHSESTIYAAAECKCTPKYYRAKKDPKTIPCTQPPSAPDNLTVTFADQFSISLTW 283
C CP +S S++ ++ C C ++RA DP CT PSAP NL ++ ++ S+SL W
Sbjct: 262 CTLCPANSHSSVRGSSVCSCRSGFHRADSDPSESVCTTIPSAPRNL-ISSVNETSLSLEW 320
Query: 284 QPPHNTGGRSDITYKI----------SCANCGPTVEFRPGETGLNSTRVTISGLDPVTEY 333
P +TGGRSD+ Y + C C V+ P GL +V + L T Y
Sbjct: 321 DEPEDTGGRSDLVYNVVCKKCLWDRSPCTRCDDNVDVAPRRLGLRQRKVVVRNLQAHTRY 380
Query: 334 KFQVYAENGVS-------ELSPDPANH-----------IEITAVTEAXXXXXXXKLRILN 375
F+V A NGVS +L +H + + + ++
Sbjct: 381 SFEVQAVNGVSGKKSAFAQLLHRQHHHQPGRQRRRLKRLLVLVCPPTAAPSAVPTVHLMR 440
Query: 376 TESDRLTIAWNPPQVDLTDPDDTIESYEVKCFPKDSQDKNTNTTLRITKDPQVTITGLRK 435
+ +D L+++W PP P+ I YE+K + +T T + + GLR
Sbjct: 441 STADTLSLSWLPPD----KPNGVILDYEIKYHERGKAMSHTVT----AQHSSARVEGLRA 492
Query: 436 DTEYGIRVRAKMKRGWGEFS 455
T Y ++VRA+ G+G +S
Sbjct: 493 ATPYVVQVRARTVAGYGRYS 512
>UniRef50_Q4SMF1 Cluster: Chromosome 8 SCAF14552, whole genome
shotgun sequence; n=8; Clupeocephala|Rep: Chromosome 8
SCAF14552, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 714
Score = 444 bits (1093), Expect = e-123
Identities = 209/388 (53%), Positives = 284/388 (73%), Gaps = 6/388 (1%)
Query: 552 GSRTYIDPHTYEDPNQAVREFAREIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEID 611
G + Y+DP TYEDP++AV+EFAREID + + IE +IG +FG+V RG+ + P E+
Sbjct: 324 GVKYYVDPSTYEDPSEAVKEFAREIDPTHLKIEEVIGAAQFGEVSRGRYR-PLG-RREVL 381
Query: 612 VAIKTLKPGSTERARRDFLAEASIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDT 671
VA+KTL+ G+++R + FL+EA ++GQF+HPNV+ L+GV+T+ P I+TEFMENG LD+
Sbjct: 382 VAVKTLRWGASDREKGMFLSEAGVLGQFDHPNVLKLEGVITRTPPERIVTEFMENGPLDS 441
Query: 672 FLRANDGKFRVLQLVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSR 731
FLR N+G+F VLQLVGMLRGI GM+YL+E N++HRDLAARNVLVNS LVCK++DFGLSR
Sbjct: 442 FLRENEGQFSVLQLVGMLRGIGAGMRYLAERNFVHRDLAARNVLVNSNLVCKVSDFGLSR 501
Query: 732 EIESTADG--AYT-TRGGKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYW 788
+ YT + G KIPVRWTAPEA RKF+SASDVWS G++ WEVMS+GERPYW
Sbjct: 502 LMRGLDHNIPTYTASLGSKIPVRWTAPEAFQHRKFSSASDVWSFGVLMWEVMSYGERPYW 561
Query: 789 NWSNQDVIKSIEKGYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLIRCPD 848
+ SNQ+V+K++ YRLPAP CP A++ LML CWQ +R RP F +++ +LD+LIR P
Sbjct: 562 DMSNQEVMKAVADQYRLPAPHSCPPALHSLMLQCWQADRGDRPAFETLLSSLDRLIRHPA 621
Query: 849 TLRKIAQNRSADPLAGDTP-DLIQFTSVEEWLECIKMSRYIEKFRAAGISDMDAVVDLTV 907
+L+ + PL TP DL ++V EWL ++M RY E+F A + +D V LT+
Sbjct: 622 SLKTEPSRSCSQPLLSPTPTDLSAVSTVHEWLRALRMERYQEEFDRAHLDTLDRVSLLTM 681
Query: 908 HQLASLGVTLVGHQKKIMNSVQSMRAQI 935
+ +LGVTL+GHQ+KI+N+ Q +RA +
Sbjct: 682 EDIQNLGVTLLGHQRKILNAAQQLRAYL 709
Score = 144 bits (349), Expect = 1e-32
Identities = 90/275 (32%), Positives = 135/275 (49%), Gaps = 21/275 (7%)
Query: 210 CAPGKFKSHTGDEHCIPCPDHSESTIYAAAECKCTPKYYRAKKDPKTIPCTQPPSAPDNL 269
C G FKS +G C CP +S ++ + C+C +YRA +D + CT PPSAP +L
Sbjct: 1 CPVGYFKSVSGSVPCSVCPSNSRTSQEGSTACECRSGFYRAARDANSSACTTPPSAPVSL 60
Query: 270 TVTF-ADQFSISLTWQPPHNTGGRSDITYKI--------------SCANCGPTVEFRPGE 314
T + + +SL W+ P + GGRS++ Y I SC+ CG V F P +
Sbjct: 61 TWEYESGDGGVSLRWRHPVDMGGRSEVWYGIVCRICPSATITNPASCSWCGEGVTFSPSQ 120
Query: 315 TGLNSTRVTISGLDPVTEYKFQVYAENGVSELSPDPANHIEITAVTEAXXXXXXXKLRIL 374
T L T+VT++ L Y QV A N VS LSP PA + I T + +L
Sbjct: 121 TNLKQTKVTLNNLLTRVTYLIQVQAMNEVSALSPFPARYTSINFTTSQSVPSTVPMMHLL 180
Query: 375 NTESDRLTIAWNPPQVDLTDPDDTIESYEVKCFPKDSQDKNTNTTLRITKDPQVTITGLR 434
+ D +T++W PQ D P+ I Y+++ + K S + + T VT+ L
Sbjct: 181 SQAPDSITLSW--PQPD--RPNGDILEYQLRYYDKGSDVDSAASVYSETN--TVTVRSLI 234
Query: 435 KDTEYGIRVRAKMKRGWGEFSGIVYARTNSVTETS 469
+ Y ++RA+ +RG+G +S VY T + E S
Sbjct: 235 AGSIYAFQIRARNERGYGPYSNTVYFTTLPLEEHS 269
>UniRef50_Q98TD0 Cluster: Ephrin receptor; n=6; Amniota|Rep: Ephrin
receptor - Gallus gallus (Chicken)
Length = 969
Score = 441 bits (1087), Expect = e-122
Identities = 209/382 (54%), Positives = 270/382 (70%), Gaps = 5/382 (1%)
Query: 554 RTYIDPHTYEDPNQAVREFAREIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVA 613
+ Y+D Y+DP++ V EF +E+D SC+T+E +IG GEFG+V RG L+LP I VA
Sbjct: 589 KPYVDLQPYDDPSRGVLEFIKELDVSCVTMENVIGEGEFGEVYRGSLRLPGK--ERIVVA 646
Query: 614 IKTLKPGSTERARRDFLAEASIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFL 673
IKTLK ++ +FL EA+IMGQF HPN++ L+GVVTK P+MIITE+MENG+LDTFL
Sbjct: 647 IKTLKSTYSDSQWWNFLREATIMGQFNHPNIVHLEGVVTKRRPMMIITEYMENGALDTFL 706
Query: 674 RANDGKFRVLQLVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREI 733
R N+ KF +QLV ML+GIA+GM YLSE NY+HRDLAARN+LV L CK++DFGLSR +
Sbjct: 707 RENEEKFSPVQLVNMLQGIASGMTYLSEHNYVHRDLAARNILVTRSLQCKVSDFGLSRIL 766
Query: 734 ESTADGAYTTRGGKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQ 793
E+ A+G Y T+GGKIP+RWTAPEAIA R FTSASDVWS GIV WEV+SFG++PY N +NQ
Sbjct: 767 ENDAEGTYETKGGKIPIRWTAPEAIAHRIFTSASDVWSFGIVMWEVLSFGDKPYGNMTNQ 826
Query: 794 DVIKSIEKGYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLIRCPDTLRKI 853
+V+KS+E GYRLP P+DCP +Y+LM CW +R RP F I L P LR +
Sbjct: 827 EVMKSLEDGYRLPPPVDCPSILYELMKSCWSHDRMRRPHFQEIRAQLQHFSSSPHLLRCV 886
Query: 854 AQNRSADPL---AGDTPDLIQFTSVEEWLECIKMSRYIEKFRAAGISDMDAVVDLTVHQL 910
A L + D I + S+ EWLE I M RYI FR AG+ M++++DLT L
Sbjct: 887 ADFDPRVTLRLPSCSGSDGIPYRSIPEWLESIPMKRYISNFRTAGLDTMESILDLTAEDL 946
Query: 911 ASLGVTLVGHQKKIMNSVQSMR 932
+GV+L GHQK+I+ S+Q +
Sbjct: 947 KQMGVSLPGHQKRILCSIQGFK 968
Score = 236 bits (577), Expect = 2e-60
Identities = 147/425 (34%), Positives = 208/425 (48%), Gaps = 28/425 (6%)
Query: 44 GNALSCKETFSLLYYEFDVATREQPPWEPESYKLVGRIAAGEGRFNTNSE---VDINTEV 100
G A++CKETF+L Y E + Q P KL +AA N + E + +NTEV
Sbjct: 113 GEAVTCKETFNLYYMESEQDVGIQFR-RPMFIKL-NTVAADRSFTNRDIESGAMQLNTEV 170
Query: 101 KSIA-VTKKGVYFAFRDQGACISILAVKVYYITCPDVNINFARFPATPTGREVTVIEQAN 159
I ++++G Y AF++ GAC+++++V+VYY TCP+ ARFP T G E + +
Sbjct: 171 CPIGKLSRRGFYLAFQNSGACVAMVSVRVYYKTCPEAVQGLARFPETLAGLEG--LTEVP 228
Query: 160 GTCVANAEVAPGEKAPVYLCKGDGKWTLPSGSCKCRAGFEPDHNNQICTECAPGKFKSHT 219
G CV A G ++ C DG+W +P G C C GFE + C C G ++
Sbjct: 229 GVCVEYAAEETGSPPRMH-CSTDGEWLVPMGRCLCAVGFEEVDGS--CVACQRGFYRHSL 285
Query: 220 GDEHCIPCPDHSESTIYAAAECKCTPKYYRAKKDPKTIPCTQPPSAPDNLTVTFADQFSI 279
+ C+ CP +S S A C C +YRA + + I CT+PPSAP N++ + +
Sbjct: 286 ETKRCLKCPPNSLSNELGATSCSCNAGFYRAPSEGQNIACTRPPSAPRNVSFSLTGT-QL 344
Query: 280 SLTWQPPHNTGGRSDITYKI--------SCANCGPTVEFRPGETGLNSTRVTISGLDPVT 331
SL WQPP + GGR D+TY + SC C P V F P +GL T V + GL+ T
Sbjct: 345 SLWWQPPSDHGGRKDLTYTVFCQRCHFLSCDPCEPGVVFSPSSSGLTKTAVDVDGLEAYT 404
Query: 332 EYKFQVYAENGVSELSPDPANHIEITAVTEAXXXXXXXKLRILNTESD-RLTIAWNPPQV 390
Y F V A NGVS + P P V IL D L+++W P+
Sbjct: 405 NYTFAVEAHNGVSGMGPAPQRTAPAVWVAVGHAAPVTVSQFILTQRDDSSLSVSWLAPR- 463
Query: 391 DLTDPDDTIESYEVKCFPKDSQDKNTNTTLRITKDPQVTITGLRKDTEYGIRVRAKMKRG 450
T YEV F K + T++ +P VT+T L+ DT Y +RVR+ G
Sbjct: 464 ---QRSRTSVEYEVMFFEKGEE---ARYTVKHLLEPNVTLTDLQPDTTYLLRVRSITPLG 517
Query: 451 WGEFS 455
G +S
Sbjct: 518 PGPYS 522
>UniRef50_UPI000065E56D Cluster: EPHB1_HUMAN Isoform 3 of P54762 -
Homo sapiens (Human); n=1; Takifugu rubripes|Rep:
EPHB1_HUMAN Isoform 3 of P54762 - Homo sapiens (Human) -
Takifugu rubripes
Length = 983
Score = 440 bits (1083), Expect = e-121
Identities = 226/392 (57%), Positives = 280/392 (71%), Gaps = 35/392 (8%)
Query: 552 GSRTYIDPHTYEDPNQAVREFAREIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEID 611
G + YIDP TYEDPN+AVREFA+EID S + IE +IG GEFG+V +G+LKLP E+
Sbjct: 617 GMKIYIDPFTYEDPNEAVREFAKEIDVSTVKIEEVIGAGEFGEVYKGRLKLPGK--RELY 674
Query: 612 VAIKTLKPGSTERARRDFLAEASIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDT 671
VAIKTLK G E+ RRDFL+EASIMGQF+HPN+I L+GVVTK P++
Sbjct: 675 VAIKTLKSGYVEKQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPLV------------- 721
Query: 672 FLRANDGKFRVLQLVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSR 731
G R G+ G+ +YLSEMNY+HRDLAARN+LVNS LVCK++DFGLSR
Sbjct: 722 ------GMMR-----GISAGM----KYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSR 766
Query: 732 EI-ESTADGAYTTR-GGKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWN 789
+ E T+D +YT+ GGKIPVRWTAPEAIA+RKFTSASDVWS GIV WEVMSFGERPYW+
Sbjct: 767 YLQEDTSDPSYTSSLGGKIPVRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSFGERPYWD 826
Query: 790 WSNQDVIKSIEKGYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLIRCPDT 849
SNQDVI +IE+ YRLP PMDCP ++QLMLDCWQK+R RP F+ IV TLDK+IR P +
Sbjct: 827 MSNQDVINAIEQDYRLPPPMDCPSTLHQLMLDCWQKDRNVRPRFADIVSTLDKMIRNPTS 886
Query: 850 LRKIAQNRS--ADPLAG-DTPDLIQFTSVEEWLECIKMSRYIEKFRAAGISDMDAVVDLT 906
L+ +A S + PL PD F+SVE+WL IKMS+Y + F +G + + V +T
Sbjct: 887 LKAVANIPSVPSQPLLDRSIPDFNTFSSVEDWLGAIKMSQYRDNFLNSGFTSLQLVAQMT 946
Query: 907 VHQLASLGVTLVGHQKKIMNSVQSMRAQIRGS 938
L +GVTL GHQKKI++++QSMR Q+ S
Sbjct: 947 SEDLLRIGVTLAGHQKKILSNIQSMRVQMSQS 978
Score = 139 bits (336), Expect = 4e-31
Identities = 75/167 (44%), Positives = 100/167 (59%), Gaps = 11/167 (6%)
Query: 48 SCKETFSLLYYEFD--VATREQPPWEPESYKLVGRIAAGEGRFNTNSE---VDINTEVKS 102
SCKETF+ YYE D +AT+ W Y V IAA E + + + +NTEV+S
Sbjct: 69 SCKETFNFYYYETDAVIATKSTAFWMEAPYLKVDTIAADESFSQVDFDGRLMKVNTEVRS 128
Query: 103 IA-VTKKGVYFAFRDQGACISILAVKVYYITCPDVNINFARFPATPTGREVTVIEQANGT 161
++K G Y AF+D GAC+S+L+V+V+Y CP V NFA FP T TG E T + A G
Sbjct: 129 FGPLSKNGFYLAFQDYGACMSLLSVRVFYKKCPSVVQNFAIFPETMTGAESTSLVIARGI 188
Query: 162 CVANAEVAPGEKAPVYL-CKGDGKWTLPSGSCKCRAGFEPDHNNQIC 207
C+ N+E P+ L C GDG+W +P GSC C+AGFE D+ N +C
Sbjct: 189 CIPNSEEV---DVPIKLYCNGDGEWMVPIGSCTCKAGFEHDNGN-VC 231
Score = 124 bits (298), Expect = 2e-26
Identities = 83/261 (31%), Positives = 116/261 (44%), Gaps = 45/261 (17%)
Query: 206 ICTECAPGKFKSHTGDEHCIPCPDHSESTIYAAAECKCTPKYYRAKKDPKTIPCTQP--- 262
+ T C PG FKS G C+ CP +S ST AA C C YYR D PCT
Sbjct: 266 VFTACPPGTFKSTQGPGLCLQCPPNSRSTAEAATVCVCRNGYYRGDADQPDEPCTSRSVM 325
Query: 263 --------------------PSAPDNLTVTFADQFSISLTWQPPHNTGGRSDITYKI--- 299
PS+P N+ ++ ++ S+ L W PP TGGR D+ Y I
Sbjct: 326 MTAFPCCTWTVASSFLSAGVPSSPRNV-ISIVNETSVILEWHPPRETGGRGDVVYNIVCK 384
Query: 300 -------SCANCGPTVEFRPGETGLNSTRVTISGLDPVTEYKFQVYAENGVSELSPDPAN 352
+C++C V+F P + GL TRV IS L T Y F++ A NGVS SP PA
Sbjct: 385 KCRADRRACSHCDDNVDFVPRQLGLTETRVFISNLLAHTLYSFEIQAVNGVSNKSPYPAQ 444
Query: 353 HIEITAVTEAXXXXXXXKLRILNTESDRLTIAWNPPQVDLTDPDDTIESYEVKCF----P 408
H+ I T + +++ + T++W P+ P+ I YE++ + P
Sbjct: 445 HVSIDITTNQAAPSIVPIMHQISSTMNSFTLSWPQPE----QPNGIILDYELRYYEKVRP 500
Query: 409 KDSQDKNTNTTLRI---TKDP 426
S N T + + T DP
Sbjct: 501 ATSASSNNATAVAVSHGTADP 521
>UniRef50_P21709 Cluster: Ephrin type-A receptor 1 precursor; n=19;
Mammalia|Rep: Ephrin type-A receptor 1 precursor - Homo
sapiens (Human)
Length = 976
Score = 414 bits (1019), Expect = e-114
Identities = 203/385 (52%), Positives = 266/385 (69%), Gaps = 12/385 (3%)
Query: 554 RTYIDPHTYEDPNQAVREFAREIDASCITIEAIIGGGEFGDVCRGKLKLPAS-CGPEIDV 612
+ Y+D YEDP Q +F RE+D + + ++ +IG GEFG+V RG L+LP+ C V
Sbjct: 597 KPYVDLQAYEDPAQGALDFTRELDPAWLMVDTVIGEGEFGEVYRGTLRLPSQDCKT---V 653
Query: 613 AIKTLKPGSTERARRDFLAEASIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTF 672
AIKTLK S +FL EA+IMGQF HP+++ L+GVVTK PIMIITEFMENG+LD F
Sbjct: 654 AIKTLKDTSPGGQWWNFLREATIMGQFSHPHILHLEGVVTKRKPIMIITEFMENGALDAF 713
Query: 673 LRANDGKFRVLQLVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSRE 732
LR + + QLV ML+GIA+GM YLS NY+HRDLAARN+LVN L CK++DFGL+R
Sbjct: 714 LREREDQLVPGQLVAMLQGIASGMNYLSNHNYVHRDLAARNILVNQNLCCKVSDFGLTRL 773
Query: 733 IESTADGAYTTRGGKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSN 792
++ DG Y T+GGKIP+RWTAPEAIA R FT+ASDVWS GIV WEV+SFG++PY SN
Sbjct: 774 LDDF-DGTYETQGGKIPIRWTAPEAIAHRIFTTASDVWSFGIVMWEVLSFGDKPYGEMSN 832
Query: 793 QDVIKSIEKGYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLIRCPDTLRK 852
Q+V+KSIE GYRLP P+DCP +Y+LM +CW +R RP F + L++L+ P +LR
Sbjct: 833 QEVMKSIEDGYRLPPPVDCPAPLYELMKNCWAYDRARRPHFQKLQAHLEQLLANPHSLRT 892
Query: 853 IAQ-----NRSADPLAGDTPDLIQFTSVEEWLECIKMSRYIEKFRAAGISDMDAVVDLTV 907
IA L+G D I + +V EWLE I+M RYI F +AG+ M+ V++LT
Sbjct: 893 IANFDPRVTLRLPSLSGS--DGIPYRTVSEWLESIRMKRYILHFHSAGLDTMECVLELTA 950
Query: 908 HQLASLGVTLVGHQKKIMNSVQSMR 932
L +G+TL GHQK+I+ S+Q +
Sbjct: 951 EDLTQMGITLPGHQKRILCSIQGFK 975
Score = 226 bits (552), Expect = 3e-57
Identities = 138/427 (32%), Positives = 209/427 (48%), Gaps = 32/427 (7%)
Query: 47 LSCKETFSLLYYEFDVATREQPPWEPESYKLVGRIAAGEG---RFNTNSEVDINTEVKSI 103
L CKETF+LLY E D Q ++ V +AA + R + V +N E S+
Sbjct: 116 LGCKETFNLLYMESDQDVGIQ--LRRPLFQKVTTVAADQSFTIRDLASGSVKLNVERCSL 173
Query: 104 A-VTKKGVYFAFRDQGACISILAVKVYYITCPDVNINFARFPATPTGREVTVIEQANGTC 162
+T++G+Y AF + GAC+++++V+V+Y CP+ A+FP T G ++E A GTC
Sbjct: 174 GRLTRRGLYLAFHNPGACVALVSVRVFYQRCPETLNGLAQFPDTLPG-PAGLVEVA-GTC 231
Query: 163 VANAEVAPGEK-APVYLCKGDGKWTLPSGSCKCRAGFEPDHNNQICTECAPGKFKSHTGD 221
+ +A +P AP C DG+W +P G C C G+E + + C C G ++
Sbjct: 232 LPHARASPRPSGAPRMHCSPDGEWLVPVGRCHCEPGYEEGGSGEACVACPSGSYRMDMDT 291
Query: 222 EHCIPCPDHSESTIYAAAECKCTPKYYRAKKDPKTIPCTQPPSAPDNLTVTFADQFSISL 281
HC+ CP S + A C C +YRA + + CT PPSAP NL+ + A +SL
Sbjct: 292 PHCLTCPQQSTAESEGATICTCESGHYRAPGEGPQVACTGPPSAPRNLSFS-ASGTQLSL 350
Query: 282 TWQPPHNTGGRSDITYKISCANC-------GPT------VEFRPGETGLNSTRVTISGLD 328
W+PP +TGGR D+ Y + C+ C GP V F PG GL + V ++GL+
Sbjct: 351 RWEPPADTGGRQDVRYSVRCSQCQGTAQDGGPCQPCGVGVHFSPGARGLTTPAVHVNGLE 410
Query: 329 PVTEYKFQVYAENGVSELSPDPANHIEITAVTEAXXXXXXXKLRILNTESDRLTIAWNPP 388
P Y F V A+NGVS L ++ LR++ E +L + W
Sbjct: 411 PYANYTFNVEAQNGVSGLGSSGHASTSVSISMGHAESLSGLSLRLVKKEPRQLELTWAGS 470
Query: 389 QVDLTDPDDTIESYEVKCFPKDSQDKNTNTTLRITKDPQVTITGLRKDTEYGIRVRAKMK 448
+ P + +YE+ +D + ++ +P+V +T L+ DT Y +RVR
Sbjct: 471 RP--RSPGANL-TYELHVLNQDEE------RYQMVLEPRVLLTELQPDTTYIVRVRMLTP 521
Query: 449 RGWGEFS 455
G G FS
Sbjct: 522 LGPGPFS 528
>UniRef50_Q4H3M7 Cluster: Ephrin receptor; n=3; Ciona|Rep: Ephrin
receptor - Ciona intestinalis (Transparent sea squirt)
Length = 1006
Score = 412 bits (1015), Expect = e-113
Identities = 201/396 (50%), Positives = 258/396 (65%), Gaps = 10/396 (2%)
Query: 553 SRTYIDPHTYEDPNQAVREFAREIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDV 612
+RTY+DP TYEDP AV+EFA+EID + IE +IG GEFG+VC+G C V
Sbjct: 618 TRTYVDPSTYEDPYNAVKEFAKEIDFKLVNIEQVIGRGEFGEVCKGTFF--NKC-----V 670
Query: 613 AIKTLKPGSTERARRDFLAEASIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTF 672
AIKTLK G + R DFL EASIMGQF+HPNVI L+GVVTK P+MIITEFMENGSLD F
Sbjct: 671 AIKTLKVGYNTQERSDFLGEASIMGQFDHPNVIRLEGVVTKSRPLMIITEFMENGSLDAF 730
Query: 673 LRANDGKFRVLQLVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSRE 732
LR +GK QL ML IA GM+YLS M Y+HRDLAARN+LVNS LVCK++DFGLSR
Sbjct: 731 LRNQEGKIPSAQLTEMLLSIAQGMEYLSNMGYVHRDLAARNILVNSNLVCKVSDFGLSRV 790
Query: 733 IESTAD---GAYTTRGGKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWN 789
+E + YTTRGG IP+RWT+PEAI R F+++SDVWS GIV WEVMSFGERPYW
Sbjct: 791 LEQLEEDDVAMYTTRGGMIPIRWTSPEAITMRTFSTSSDVWSFGIVMWEVMSFGERPYWE 850
Query: 790 WSNQDVIKSIEKGYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLIRCPDT 849
SNQDV++ ++ GYRLP P CP ++ +ML+CW+++RT RP FS +V LD+ + D
Sbjct: 851 MSNQDVVQFVDSGYRLPPPCYCPRIIHSVMLECWKRDRTQRPNFSHLVTLLDRFLLEADC 910
Query: 850 LRKIAQNRSADPLAGDTPDLIQFTSVEEWLECIKMSRYIEKFRAAGISDMDAVVDLTVHQ 909
L NR P+++ +S+ +WLE + M +Y G + ++ LT
Sbjct: 911 LTDTINNRPFRDQDDCIPEMLDLSSLGQWLEQMHMLKYKPTMMRHGCVTAEQIIRLTASG 970
Query: 910 LASLGVTLVGHQKKIMNSVQSMRAQIRGSGPYGFLV 945
LA +G + + ++ +R +I G G V
Sbjct: 971 LAHMGFSDMNDVNIVLREADLLRQKIEEVGNVGVAV 1006
Score = 262 bits (643), Expect = 2e-68
Identities = 148/435 (34%), Positives = 223/435 (51%), Gaps = 24/435 (5%)
Query: 47 LSCKETFSLLYYEFD-VATREQPPWEPESYKLVGRIAAGEGRFNTNSEVDINTEVKSIA- 104
+SCKETF+L Y E + + R ++Y V IAA E RF ++ V+ NTE + I+
Sbjct: 107 VSCKETFNLYYLESNHMNDRRSLRLNEDTYTKVDTIAADE-RFKPDTRVEANTETRMISP 165
Query: 105 VTKKGVYFAFRDQGACISILAVKVYYITCPDVNINFARFPATPTGREVTVIEQANGTCVA 164
+ +G+Y AF+D GAC+SI+ V+VYY +C + A FP T +G +T + G CV
Sbjct: 166 IRSRGLYIAFQDTGACMSIMHVRVYYKSCQETLRGLAIFPPTVSGPMMTSLVDVPGQCVP 225
Query: 165 NAEVAPGEKAPVYLCKGDGKWTLPSGSCKCRAGFEPDHNNQICTECAPGKFKSHTGDEHC 224
N+ KAP C G+G+W +P+GSC C G+EP++ C +C G+FK G+ C
Sbjct: 226 NSATMKNTKAPSLHCNGEGEWLVPTGSCSCNPGYEPNNQLTECNQCRVGRFKHEVGNVPC 285
Query: 225 IPCPDHSESTIYAAAECKCTPKYYRAKKDPKTIPCTQPPSAPDNLTVTFADQFSISLTWQ 284
PCP S + +A+ C C YYR+ D PCT+ PS P L + ++ S+ LTW
Sbjct: 286 QPCPARSFNVNFASTMCMCISGYYRSPGDRPDAPCTRTPSKPSTLE-SSVNKTSVKLTWV 344
Query: 285 PPHNTGGRSDITYKIS----------CANCGPTVEFRPGETGLNSTRVTISGLDPVTEYK 334
P GGR+DITY ++ C+ CG +F PG T L + + L P T+YK
Sbjct: 345 EPRKNGGRTDITYSVTCERCDATYTLCSRCGEGADFIPGRTRLTKGSLLVRDLAPHTDYK 404
Query: 335 FQVYAENGVSELSPDPANHIEITAVTEAXXXXXXXKLRILNTESDRLTIAWNPPQVDLTD 394
F+VY+ NGVS +S EI T +R++ S + + W+PP+
Sbjct: 405 FKVYSFNGVSGVSGLRPAFAEIRIRTNQAAPSAVQPVRVVMATSAEVLLQWSPPRYS--- 461
Query: 395 PDDTIESYEVKCFPKDSQDKNTNTTLRITKDPQVTITGLRKDTEYGIRVRAKMKRGWGEF 454
+ I Y+++ TN T + T ++ L T Y ++VRA+ K G+G +
Sbjct: 462 -SNPILDYQIQY--SSIHGLFTNVTTKTT----YKLSNLSPSTSYIVQVRARSKVGYGLY 514
Query: 455 SGIVYARTNSVTETS 469
S RT V ++
Sbjct: 515 SRASAFRTKPVKSST 529
>UniRef50_UPI000065E468 Cluster: Homolog of Gallus gallus "Ephrin
type-A receptor 7 precursor (EC 2.7.1.112)
(Tyrosine-protein kinase receptor CEPHA7)
(Tyrosine-protein kinase receptor CEK11).; n=5;
Euteleostomi|Rep: Homolog of Gallus gallus "Ephrin type-A
receptor 7 precursor (EC 2.7.1.112) (Tyrosine-protein
kinase receptor CEPHA7) (Tyrosine-protein kinase receptor
CEK11). - Takifugu rubripes
Length = 1037
Score = 406 bits (1000), Expect = e-111
Identities = 207/399 (51%), Positives = 272/399 (68%), Gaps = 21/399 (5%)
Query: 554 RTYIDPHTYEDPNQAVREFAREIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVA 613
RTYIDP T ED QAV FA+E+D S I IE I+ G+FG+VCRG LKLP+ E+ VA
Sbjct: 633 RTYIDPETCEDLLQAVHAFAKELDNSSIKIERIVHTGDFGEVCRGCLKLPSK--RELPVA 690
Query: 614 IKTLKPGSTERARRDFLAEASIMGQFEHPNVIFLQGVVTK----------CNP----IMI 659
IKTL+ G +++ RR FL+EA I+GQF+H N+I L+GV+T C P +MI
Sbjct: 691 IKTLRAGCSDKQRRSFLSEAGILGQFDHTNIIRLEGVITTVLLLHAPLSFCAPAGNTMMI 750
Query: 660 ITEFMENGSLDTFLRANDGKFRVLQLVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQ 719
I E M NG+LD+FLR ++G+ V+QL+ ML G+A+GM+YL+EM ++H+ LAA VLVNS
Sbjct: 751 IEESMSNGALDSFLRKHEGQLSVMQLMDMLTGVASGMKYLTEMGFVHKRLAAHKVLVNSN 810
Query: 720 LVCKIADFGLSREIESTADGAYTT-RGGKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWE 778
L CK++ F +E + YTT GGK V WTAPEAI + +F+SASDVWS GIV WE
Sbjct: 811 LGCKVSGFRPLQE--DKIEAIYTTLHGGKSVVLWTAPEAIQYHRFSSASDVWSFGIVMWE 868
Query: 779 VMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVK 838
VMS+GERPYW+ NQDVIK+IE G+RLPAP++CP ++QLMLDCWQKERT RP+FS I
Sbjct: 869 VMSYGERPYWDMGNQDVIKAIEDGFRLPAPVNCPPHLHQLMLDCWQKERTERPSFSQIHS 928
Query: 839 TLDKLIRCPDTLRKIAQNRSADPLAGD--TPDLIQFTSVEEWLECIKMSRYIEKFRAAGI 896
L K IR PD + RS+ D P F SV EWL+ + M RY + F AAG
Sbjct: 929 ALSKSIRSPDGIGSSTLARSSSITLADRPLPSFPAFNSVGEWLDAVDMGRYKDNFTAAGY 988
Query: 897 SDMDAVVDLTVHQLASLGVTLVGHQKKIMNSVQSMRAQI 935
+++V +TV + SLG+T + HQK I+ ++QS+RAQ+
Sbjct: 989 CYLESVARMTVQDVLSLGITSLEHQKLILAAIQSLRAQV 1027
Score = 215 bits (524), Expect = 6e-54
Identities = 122/335 (36%), Positives = 176/335 (52%), Gaps = 26/335 (7%)
Query: 42 VNGNALSCKETFSLLYYEFDV----ATREQPPWEPESYKLVGRIAAGEGRFNTN---SEV 94
+ G A +CKETF+LLY E D TRE + Y + IAA E + ++
Sbjct: 81 IPGVAGTCKETFNLLYVESDRDLGGVTRE------DRYTKIDTIAADESFTQGDLGERKM 134
Query: 95 DINTEVKSIA-VTKKGVYFAFRDQGACISILAVKVYYITCPDVNINFARFPATPTGREVT 153
+NTEV+ I + +KG + AF+D GAC++++AV+VYY C N A FP T +
Sbjct: 135 KLNTEVREIGHLNRKGFHLAFQDVGACVALVAVRVYYKRCLATVQNLAVFPDTVSEAAFA 194
Query: 154 VIEQANGTCVANAEVAPGEKAPVYLCKGDGKWTLPSGSCKCRAGFEPDHNNQICTECAPG 213
+ + G+CV N+EV + P C +G+W +P G C C AG+E H++ C C PG
Sbjct: 195 TLVEVRGSCVNNSEVDT-DSPPRMHCSAEGEWLVPIGKCSCSAGYEEGHSS--CEACPPG 251
Query: 214 KFKSHTGDEHCIPCPDHSESTIYAAAECKCTPKYYRAKKDPKTIPCTQPPSAPDNLTVTF 273
+K + + C PCP +S + + C C ++R D + PCT+PPS P +L T
Sbjct: 252 SYKMSSRQQECFPCPANSVADEDGSVVCVCKEDHFRTPLDTPSAPCTRPPSPPRDLICTL 311
Query: 274 ADQFSISLTWQPPHNTGGRSDITYKISCAN--------CGPTVEFRPGETGLNSTRVTIS 325
Q ++ L W P +TGGRSD+TY ++C CG +V F P + GL VT+
Sbjct: 312 -KQSTLILEWAAPSDTGGRSDLTYSVACQRCMTRHCEPCGSSVGFVPQQVGLTERTVTVV 370
Query: 326 GLDPVTEYKFQVYAENGVSELSPDPANHIEITAVT 360
L P T Y F V A NGVSEL P+ ++ T
Sbjct: 371 NLLPNTNYTFTVEALNGVSELLPNKRFFTQVNVST 405
>UniRef50_Q9Y1Y3 Cluster: Protein tyrosine kinase; n=1; Ephydatia
fluviatilis|Rep: Protein tyrosine kinase - Ephydatia
fluviatilis
Length = 893
Score = 402 bits (989), Expect = e-110
Identities = 197/388 (50%), Positives = 254/388 (65%), Gaps = 10/388 (2%)
Query: 552 GSRTYIDPHTYEDPNQAVREFAREIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEID 611
G+R Y+DP TY+ QAV A EI I + IGGGEFG V +G P +
Sbjct: 506 GTRMYVDPRTYQSTTQAVSTVATEIPPKYIKLVEEIGGGEFGTVYKGMWN---ERKPPVP 562
Query: 612 VAIKTLKPGSTERARRDFLAEASIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDT 671
+A+KTLKPGS+++ R DFL EASIMGQF HPNVI L GV+TK P MII EFM+NGSL
Sbjct: 563 IAVKTLKPGSSDKMRDDFLTEASIMGQFHHPNVIKLYGVITKVEPAMIIMEFMDNGSLYY 622
Query: 672 FLRANDGKFRVLQLVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSR 731
+LR ND K + QL+ M G+A GMQYLSE+ Y+HRDLAARN+LV+ VCK+ADFGLSR
Sbjct: 623 YLRHNDEKLSLQQLLKMACGVAAGMQYLSEVGYVHRDLAARNILVSKDEVCKVADFGLSR 682
Query: 732 EIESTADGAYTTRGGKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWS 791
E+T D +GGKIPVRWTAPEAI++RKFT+ASDVWS G++ WEVMS+G++PY +W
Sbjct: 683 --ETTNDEYDVKKGGKIPVRWTAPEAISYRKFTTASDVWSYGVLLWEVMSYGQQPYEDWD 740
Query: 792 NQDVIKSIEKGYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLIRCPD--- 848
NQ V+ +E GYRL P DCP VY+LM CW E T RPTF +V+ LD ++ +
Sbjct: 741 NQMVLDKLESGYRLQKPKDCPSTVYELMQSCWSAEHTDRPTFKELVRLLDAMLESNNKDA 800
Query: 849 TLRKIAQNRSADPLAGDTPDLIQFTSVEEWLECIKMSRYIEKFRAAGISDMDAVVDLTVH 908
+ K R L TP + + S+E WLE IKM RY++ F + G+ + V+ L
Sbjct: 801 PIPKPRTRRGTFGLGRKTP--LDYQSIEAWLEAIKMDRYVQNFHSQGLKSIQDVLLLAEE 858
Query: 909 QLASLGVTLVGHQKKIMNSVQSMRAQIR 936
L +GV + GH KIM+SV+ Q++
Sbjct: 859 DLRGMGVAIPGHVNKIMSSVRGAHQQMQ 886
Score = 152 bits (369), Expect = 4e-35
Identities = 81/257 (31%), Positives = 126/257 (49%), Gaps = 13/257 (5%)
Query: 109 GVYFAFRDQGACISILAVKVYYITCPDVNINFARFPATPTGREVTVIEQANGTCVANAEV 168
G+Y A ++ G C+SI + V++ CP +NF +P + +T + CV+ A +
Sbjct: 195 GMYLAAQETGTCVSISRLIVFHYMCPQQVVNFISYPMAMSNGAITQL-----ACVSGASL 249
Query: 169 APGEKAPVYLCKGDGKWTLPSGSCKCRAGFEPDHNNQICTECAPGKFKSHTGDEHCIPCP 228
G + P+ C G W P+G C C G+ Q C C PG +KS G C+PCP
Sbjct: 250 V-GVQLPLATCGSQGVWGAPNGGCSCNFGYTSI--GQSCQSCPPGTYKSVQGSSVCLPCP 306
Query: 229 DHSESTIYAAAECKCTPKYYRAKKDPKTIPC--TQPPSAPDNLTVTFADQFSISLTWQPP 286
+S S++ +++C C P YYR C ++PPSAP NL A S+ L+W PP
Sbjct: 307 SNSNSSVNGSSQCPCLPGYYRPASSGADSDCIASRPPSAPQNLNKGAASATSVVLSWSPP 366
Query: 287 HNTGGRSDITYKISC-ANCGPTVEFRPGETGLNSTRVTISGLDPVTEYKFQVYAENGVSE 345
++GG + Y + A ++ G + +T VT++ L P TEY V A+NG
Sbjct: 367 QDSGGTGIVLYTVYYQAIISGSLRMTWG--NVTTTSVTVTNLLPATEYIMTVVAQNGEPG 424
Query: 346 LSPDPANHIEITAVTEA 362
D + + +T + A
Sbjct: 425 DEADRSVSLRVTTLNTA 441
>UniRef50_Q4H3M3 Cluster: Ephrin receptor like protein; n=1; Ciona
intestinalis|Rep: Ephrin receptor like protein - Ciona
intestinalis (Transparent sea squirt)
Length = 1085
Score = 396 bits (976), Expect = e-108
Identities = 293/908 (32%), Positives = 422/908 (46%), Gaps = 104/908 (11%)
Query: 33 VEVHVGYEHVNGNALSCKETFSLLYYEFDVATREQPPWEPESYKLVGRIAAGEGRFNTNS 92
VE++ C ETF + YY E P + + +AA + ++NS
Sbjct: 112 VELNFWMRECENKDTICPETFKI-YYAITSHQSEVPQLNESVFTKIDTVAAEDQFADSNS 170
Query: 93 EVD--INTEV------KSIAVTKKGVYFAFRDQGACISILAVKVYYITCPDVNINFARFP 144
+ +NTE+ +SI ++ GVY A D+GACI++++V+VY I CP + A FP
Sbjct: 171 DWTEVLNTEIVNIEIPQSIDISHAGVYVAIVDKGACIALVSVRVYSIVCPMEIQSLAIFP 230
Query: 145 ATPTGREVTVIEQANGTCVANAEVAPGEKA--PVYLCKGDGKWTLPSGSCKCRAGFEPDH 202
T TG T + + NG+CV + A E + PV C DG+W + +G+C C AG++PDH
Sbjct: 231 ETLTGELDTSLVKVNGSCVERSHPANSEVSSQPVNHCTSDGRWNVRTGACYCEAGYQPDH 290
Query: 203 N-----------------NQICTECAPGKFKSHTGDEHCIPCPDHSESTIYAAAECKCTP 245
N N CT+C + H G C+ H ST Y C P
Sbjct: 291 NMRTCQPCPRNMYKPTSGNLNCTKCPSVSYTHHVGSISCVCSDGHLVSTSYLDG-CGVCP 349
Query: 246 KYYRAKKDPKTIPCTQPPSA-------PDNL------------TVTFADQFSISLTWQPP 286
+ K I T P A P + V + S SL+ Q
Sbjct: 350 QLPSPPLKLKVIKSTTVPGAARLEWEKPQDFGNCQKIFYCVLCQVHSINHASTSLSKQNN 409
Query: 287 HNT-GGRSDITYKISCANCGPTVEFRPGETGLNSTRVTISGLDPVTEYKFQVYAENGVSE 345
+++ +SD T + V + P + L + V + L Y FQV A N V+
Sbjct: 410 NSSLFKQSDPTQPSYTVDACDGVLYYPHQCSLKTNFVDMHNLTGHGLYTFQVVATNAVTH 469
Query: 346 ----------------LSPDPANHIE--ITAVTEAXXXXXXXKLRILNTESDRLTIAWNP 387
L+P +N +T + L ++++ +TI WNP
Sbjct: 470 KHADSITGQDAVRNKMLNPKVSNTSSAFVTFSIDKFHPSTPTNLHMIHSNYTSVTIQWNP 529
Query: 388 PQVDLTDPDDTIESYEVKCFPKDSQDKNTNTTLRITKDPQ----VTITG-----LRKDTE 438
P T D SY++ +++K L+ T P V +T L
Sbjct: 530 PVY--TSGDQI--SYKIVWVENQARNKTAILQLKSTTLPTSHMLVNVTRAHLAQLNSGVN 585
Query: 439 YGIRVRAKMKRGWGEFSGIVYARTNSVTETSFIDEEGAQXXXXXXXXXXXXXXXXXXXXX 498
Y I V+A G +S ++ RT S TS +
Sbjct: 586 YYIAVQALSTAGQSNYSSVLEVRTMSSDLTSKPTGKPNNSNDSLYVYLVAVVSVLLFGGF 645
Query: 499 XXXFLRSRADDECDKKQPSDCNALNYRNGEVYTGPDRPAKTSSNATTPLFAGT---GSRT 555
FL R K++ C D+P ++SS T RT
Sbjct: 646 VFFFLWRRCRGTSGKQKSKPCL-------------DKPLQSSSEECDGFTVCTELSDQRT 692
Query: 556 YIDPHTYEDPNQAVREFAREIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPE--IDVA 613
Y+DP + P Q +F+ E D ++I +IG GEFG+V +G L L + G IDVA
Sbjct: 693 YVDPFSC-GPIQT-HKFSCETDPDLVSINKVIGCGEFGEVYQGSLTLTDTGGKRKVIDVA 750
Query: 614 IKTLKPGSTERARRDFLAEASIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFL 673
IK L + DFL EA + +F+HPN++ L+ VV P MI+TE M NG L FL
Sbjct: 751 IKQLHAQCQPNEQIDFLHEAKALERFQHPNIVKLEAVVMASRPFMIVTELMVNGCLGKFL 810
Query: 674 RANDGK---FRVLQLVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLS 730
R + G F+ LV ML G+A GM YLS+M Y+HRDLAARNVL+N++LVCK+ADFGL
Sbjct: 811 RHHRGAKRYFKPTVLVRMLHGVAKGMAYLSKMCYVHRDLAARNVLINNELVCKVADFGLI 870
Query: 731 REIESTADGAYTTRGGKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNW 790
R I T+GGKI +RWTAPEA+A++ ++ ASDVWS G+ WEV+++GE+PYW+
Sbjct: 871 RHI-GEKKSTVNTKGGKISLRWTAPEAVAYQAYSQASDVWSFGVFAWEVITYGEKPYWSL 929
Query: 791 SNQDVIKSIEKGYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLIRCPDTL 850
+NQ V+++I GYRLPAP DCP ++QLML+CW +++ RPTF +V LD +I L
Sbjct: 930 TNQQVLQAINDGYRLPAPEDCPSVLHQLMLECWHRDKNTRPTFEQVVTRLDAMINQRGVL 989
Query: 851 RKIAQNRS 858
+A S
Sbjct: 990 DTLASPAS 997
>UniRef50_Q9UF33 Cluster: Ephrin type-A receptor 6 precursor; n=57;
Euteleostomi|Rep: Ephrin type-A receptor 6 precursor -
Homo sapiens (Human)
Length = 1035
Score = 378 bits (931), Expect = e-103
Identities = 171/291 (58%), Positives = 221/291 (75%), Gaps = 1/291 (0%)
Query: 656 PIMIITEFMENGSLDTFLRANDGKFRVLQLVGMLRGIATGMQYLSEMNYIHRDLAARNVL 715
P+MI+ E+MENGSLD+FLR +DG F V+QLVGMLRGIA+GM+YLS+M Y+HRDLAARN+L
Sbjct: 745 PVMIVVEYMENGSLDSFLRKHDGHFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNIL 804
Query: 716 VNSQLVCKIADFGLSREIESTADGAYTTRGGKIPVRWTAPEAIAFRKFTSASDVWSMGIV 775
VNS LVCK++DFGLSR +E + AYTT GGKIP+RWTAPEAIA+RKF+SASD WS GIV
Sbjct: 805 VNSNLVCKVSDFGLSRVLEDDPEAAYTTTGGKIPIRWTAPEAIAYRKFSSASDAWSYGIV 864
Query: 776 CWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSS 835
WEVMS+GERPYW SNQDVI SIE+GYRLPAPM CP +++QLML CWQKER HRP F+
Sbjct: 865 MWEVMSYGERPYWEMSNQDVILSIEEGYRLPAPMGCPASLHQLMLHCWQKERNHRPKFTD 924
Query: 836 IVKTLDKLIRCPDTLRKIAQNRSADPLA-GDTPDLIQFTSVEEWLECIKMSRYIEKFRAA 894
IV LDKLIR P L + ++ P + G+ P+ F +V +WL+ IKM +Y F AA
Sbjct: 925 IVSFLDKLIRNPSALHTLVEDILVMPESPGEVPEYPLFVTVGDWLDSIKMGQYKNNFVAA 984
Query: 895 GISDMDAVVDLTVHQLASLGVTLVGHQKKIMNSVQSMRAQIRGSGPYGFLV 945
G + D + +++ + +GV L+GHQ++I++S+Q++R + GF V
Sbjct: 985 GFTTFDLISRMSIEDIRRIGVILIGHQRRIVSSIQTLRLHMMHIQEKGFHV 1035
Score = 242 bits (593), Expect = 3e-62
Identities = 137/422 (32%), Positives = 214/422 (50%), Gaps = 28/422 (6%)
Query: 48 SCKETFSLLYYEFDVATREQPPWEPESYKLVGRIAAGEG--RFNTNSEV-DINTEVKSIA 104
+CKETF+L Y E D + + ++P Y + IAA E + + + +NTE++ +
Sbjct: 119 TCKETFNLFYMESDESHGIK--FKPNQYTKIDTIAADESFTQMDLGDRILKLNTEIREVG 176
Query: 105 -VTKKGVYFAFRDQGACISILAVKVYYITCPDVNINFARFPATPTGREVTVIEQANGTCV 163
+ +KG Y AF+D GACI++++V+V+Y CP N A FP T + + + + G+CV
Sbjct: 177 PIERKGFYLAFQDIGACIALVSVRVFYKKCPFTVRNLAMFPDTIPRVDSSSLVEVRGSCV 236
Query: 164 ANAEVAPGEKAPVYLCKGDGKWTLPSGSCKCRAGFEPDHNNQICTECAPGKFKSHTGDEH 223
+AE P C DG W +P G C C G+E + C C PG +K+ G+
Sbjct: 237 KSAEE---RDTPKLYCGADGDWLVPLGRCICSTGYEEIEGS--CHACRPGFYKAFAGNTK 291
Query: 224 CIPCPDHSESTIYAAAECKCTPKYYRAKKDPKTIPCTQPPSAPDNLTVTFADQFSISLTW 283
C CP HS + + A + C+C Y+RA+KDP ++ CT PPSAP N+ ++ ++ L W
Sbjct: 292 CSKCPPHSLTYMEATSVCQCEKGYFRAEKDPPSMACTGPPSAPRNVVFNI-NETALILEW 350
Query: 284 QPPHNTGGRSDITYKI----------SCANCGPTVEFRPGETGLNSTRVTISGLDPVTEY 333
PP +TGGR D+TY + C +CG + F P TGL + V + Y
Sbjct: 351 SPPSDTGGRKDLTYSVICKKCGLDTSQCEDCGGGLRFIPRHTGLINNSVIVLDFVSHVNY 410
Query: 334 KFQVYAENGVSELSPDPANHIEITAVTEAXXXXXXXKLRILNTESDRLTIAWNPPQVDLT 393
F++ A NGVSELS P IT T+ +R + + ++W P
Sbjct: 411 TFEIEAMNGVSELSFSPKPFTAITVTTDHDAPSLIGMMRKDWASQNSIALSWQAPAFS-- 468
Query: 394 DPDDTIESYEVKCFPKDSQDKNTNTTLRITKDPQVTITGLRKDTEYGIRVRAKMKRGWGE 453
+ I YE+K + K+ + ++T +K P V ITGL+ T+Y +R + G+
Sbjct: 469 --NGAILDYEIKYYEKEHEQLTYSSTR--SKAPSVIITGLKPATKYVFHIRVRTATGYSG 524
Query: 454 FS 455
+S
Sbjct: 525 YS 526
Score = 140 bits (340), Expect = 1e-31
Identities = 69/102 (67%), Positives = 79/102 (77%), Gaps = 2/102 (1%)
Query: 552 GSRTYIDPHTYEDPNQAVREFAREIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEID 611
G +TYIDP TYEDP+ AV EFA+EID S I IE +IG GEFG+VC G+LK P EI
Sbjct: 601 GIKTYIDPDTYEDPSLAVHEFAKEIDPSRIRIERVIGAGEFGEVCSGRLKTPGK--REIP 658
Query: 612 VAIKTLKPGSTERARRDFLAEASIMGQFEHPNVIFLQGVVTK 653
VAIKTLK G +R RRDFL EASIMGQF+HPN+I L+GVVTK
Sbjct: 659 VAIKTLKGGHMDRQRRDFLREASIMGQFDHPNIIRLEGVVTK 700
>UniRef50_Q5JZY3 Cluster: Ephrin type-A receptor 10 precursor; n=10;
Eutheria|Rep: Ephrin type-A receptor 10 precursor - Homo
sapiens (Human)
Length = 1008
Score = 367 bits (904), Expect = e-100
Identities = 177/392 (45%), Positives = 260/392 (66%), Gaps = 10/392 (2%)
Query: 554 RTYIDPHTYEDPNQAVREFAREIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVA 613
RT++DP + D QAV FA+E+DA +T+E +GGG FG++C G L+LP E+ VA
Sbjct: 618 RTFLDPQSCGDLLQAVHLFAKELDAKSVTLERSLGGGRFGELCCGCLQLPGR--QELLVA 675
Query: 614 IKTLKPGSTERARRDFLAEASIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFL 673
+ L+ +++ R FLAEA +GQF+H +++ L+GVVT+ + +MI+TE+M +G+LD FL
Sbjct: 676 VHMLRDSASDSQRLGFLAEALTLGQFDHSHIVRLEGVVTRGSTLMIVTEYMSHGALDGFL 735
Query: 674 RANDGKFRVLQLVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREI 733
R ++G+ QL+G+L G+A+ M+YLSEM Y+HR LAAR+VLV+S LVCKI+ FG R
Sbjct: 736 RRHEGQLVAGQLMGLLPGLASAMKYLSEMGYVHRGLAARHVLVSSDLVCKISGFG--RGP 793
Query: 734 ESTADGAYTTRGGKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQ 793
++ YTT G+ P W APE + F F+SASDVWS GI+ WEVM+FGERPYW+ S Q
Sbjct: 794 RDRSEAVYTTMSGRSPALWAAPETLQFGHFSSASDVWSFGIIMWEVMAFGERPYWDMSGQ 853
Query: 794 DVIKSIEKGYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLIRCPDTLRKI 853
DVIK++E G+RLP P +CP +++LMLDCWQK+ RP FS I L K+++ P+ +
Sbjct: 854 DVIKAVEDGFRLPPPRNCPNLLHRLMLDCWQKDPGERPRFSQIHSILSKMVQDPEPPKCA 913
Query: 854 AQN--RSADPLAGDT-PDLIQFTSVEEWLECIKMSRYIEKFRAAGISDMDAVVDLTVHQL 910
R PLA F SV WLE + + RY + F AAG ++AV ++T L
Sbjct: 914 LTTCPRPPTPLADRAFSTFPSFGSVGAWLEALDLCRYKDSFAAAGYGSLEAVAEMTAQDL 973
Query: 911 ASLGVTLVGHQKKIMNSVQSMRA---QIRGSG 939
SLG++L H++ +++ + +++A Q++G G
Sbjct: 974 VSLGISLAEHREALLSGISALQARVLQLQGQG 1005
Score = 223 bits (544), Expect = 2e-56
Identities = 133/423 (31%), Positives = 209/423 (49%), Gaps = 25/423 (5%)
Query: 42 VNGNALSCKETFSLLYYEFDVAT-REQPPWEPESYKLVGRIAAGEGRFNTN---SEVDIN 97
+ G A +CKETF++ Y E + R +P + + IAA E + ++ +N
Sbjct: 115 IPGAAGTCKETFNVYYLETEADLGRGRPRLGGSRPRKIDTIAADESFTQGDLGERKMKLN 174
Query: 98 TEVKSIA-VTKKGVYFAFRDQGACISILAVKVYYITCPDVNINFARFPATPTGREVTVIE 156
TEV+ I ++++G + AF+D GAC+++++V+VYY C A FPAT + +
Sbjct: 175 TEVREIGPLSRRGFHLAFQDVGACVALVSVRVYYKQCRATVRGLATFPATAAESAFSTLV 234
Query: 157 QANGTCVANAEVAPGEKAPVYLCKGDGKWTLPSGSCKCRAGFEPDHNNQICTECAPGKFK 216
+ GTCVA++E PG ++ C DG+W +P G C C AGF+ C C PG +K
Sbjct: 235 EVAGTCVAHSEGEPGSPPRMH-CGADGEWLVPVGRCSCSAGFQ--ERGDFCEACPPGFYK 291
Query: 217 SHTGDEHCIPCPDHSESTIYAAAECKCTPKYYRAKKDPKTIPCTQPPSAPDNLTVTFA-D 275
C PCP+HS + A+ C C Y R+ DP + CT+PPSAP +L + +
Sbjct: 292 VSPRRPLCSPCPEHSRALENASTFCVCQDSYARSPTDPPSASCTRPPSAPRDLQYSLSRS 351
Query: 276 QFSISLTWQPPHNTGGRSDITYKI------------SCANCGPTVEFRPGETGLNSTRVT 323
+ L W PP ++GGRSD+TY + +C CGP V F P + GL T
Sbjct: 352 PLVLRLRWLPPADSGGRSDVTYSLLCLRCGREGPAGACEPCGPRVAFLPRQAGLRERAAT 411
Query: 324 ISGLDPVTEYKFQVYAENGVS-ELSPDPANHIEITAVTEAXXXXXXXKLRILNTESDRLT 382
+ L P Y +V A NGVS + + ++T T ++R E ++
Sbjct: 412 LLHLRPGARYTVRVAALNGVSGPAAAAGTTYAQVTVSTGPGAPWEEGEIRRDRVEPQSVS 471
Query: 383 IAWNPPQVDLTDPDDTIESYEVKCFPKDSQDKNTNTTLRITKDPQVTITGLRKDTEYGIR 442
++W P + P YE++ + K Q + + ++ T P VT+T L+ T Y +
Sbjct: 472 LSWREP-IPAGAPGANDTEYEIRYYEK-GQSEQAYSMVK-TGAPTVTVTNLKPATRYVFQ 528
Query: 443 VRA 445
+RA
Sbjct: 529 IRA 531
>UniRef50_O15197 Cluster: Ephrin type-B receptor 6 precursor; n=25;
Amniota|Rep: Ephrin type-B receptor 6 precursor - Homo
sapiens (Human)
Length = 1006
Score = 360 bits (886), Expect = 9e-98
Identities = 181/393 (46%), Positives = 247/393 (62%), Gaps = 17/393 (4%)
Query: 550 GTGSRTYIDPHTYEDPNQAVREFAREIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPE 609
G G + YIDP TYEDP QA+RE ARE+D + I IE +IG G FG+V +G+L+ P E
Sbjct: 624 GLGVKYYIDPSTYEDPCQAIRELAREVDPAYIKIEEVIGTGSFGEVRQGRLQ-PRG-RRE 681
Query: 610 IDVAIKTLKPGSTERARRDFLAEASIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSL 669
VAI+ L G E + FL A+++GQF+HPN++ L+GVVTK P+M++TEFME G L
Sbjct: 682 QTVAIQALWAGGAESLQMTFLGRAAVLGQFQHPNILRLEGVVTKSRPLMVLTEFMELGPL 741
Query: 670 DTFLRANDGKFRVLQLVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGL 729
D+FLR +G+F LQLV M RG+A MQYLS ++HR L+A +VLVNS LVCK+A G
Sbjct: 742 DSFLRQREGQFSSLQLVAMQRGVAAAMQYLSSFAFVHRSLSAHSVLVNSHLVCKVARLG- 800
Query: 730 SREIESTADGAYTTRGGKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWN 789
++ +G +RW APE IA K T++SDVWS GI+ WEVMS+GERPYW+
Sbjct: 801 -----------HSPQGPSCLLRWAAPEVIAHGKHTTSSDVWSFGILMWEVMSYGERPYWD 849
Query: 790 WSNQDVIKSIEKGYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLIRCPDT 849
S Q+V+ +IE+ +RLP P CP ++ LMLD WQK+R RP F +V DK+IR PDT
Sbjct: 850 MSEQEVLNAIEQEFRLPPPPGCPPGLHLLMLDTWQKDRARRPHFDQLVAAFDKMIRKPDT 909
Query: 850 LRKIAQNRSADPLAGDTPDLIQF---TSVEEWLECIKMSRYIEKFRAAGISDMDAVVDLT 906
L+ A TP + F S + WL I + Y + F G+ V L+
Sbjct: 910 LQAGGDPGERPSQALLTPVALDFPCLDSPQAWLSAIGLECYQDNFSKFGLCTFSDVAQLS 969
Query: 907 VHQLASLGVTLVGHQKKIMNSVQSMRAQIRGSG 939
+ L +LG+TL GHQKK+++ +Q ++ +R G
Sbjct: 970 LEDLPALGITLAGHQKKLLHHIQLLQQHLRQQG 1002
Score = 221 bits (540), Expect = 7e-56
Identities = 135/407 (33%), Positives = 202/407 (49%), Gaps = 33/407 (8%)
Query: 82 AAGEGRFNTNSEVDINTEVKSIA-VTKKGVYFAFRDQGACISILAVKVYYITCPDVNINF 140
A G + + +N + +S +T++G Y AF+D GAC++++AV+++ TCP V +F
Sbjct: 165 AVGPHGAGQRAGLQLNVKERSFGPLTQRGFYVAFQDTGACLALVAVRLFSYTCPAVLRSF 224
Query: 141 ARFPATP-TGREVTVIEQANGTCVANAEVAP-------GEKAPVYLCKGDGKWTLPSGSC 192
A FP T +G + A GTCVA+AE G P C G+GKW + G C
Sbjct: 225 ASFPETQASGAGGASLVAAVGTCVAHAEPEEDGVGGQAGGSPPRLHCNGEGKWMVAVGGC 284
Query: 193 KCRAGFEPDHNNQICTECAPGKFKSHTGDEHCIPCPDHSESTIYAAAECKCTPKYYRAKK 252
+C+ G++P ++ C C G +KS G+ C PCP S + AA C C +YRA
Sbjct: 285 RCQPGYQPARGDKACQACPRGLYKSSAGNAPCSPCPARSHAPNPAAPVCPCLEGFYRASS 344
Query: 253 DPKTIPCTQPPSAPDNLTVTFADQFSISLTWQPPHNTGGRSDITYKISCANC-------- 304
DP PCT PPSAP L ++ L W+ P GGR D+ + + C C
Sbjct: 345 DPPEAPCTGPPSAPQELWFEVQGS-ALMLHWRLPRELGGRGDLLFNVVCKECEGRQEPAS 403
Query: 305 --GPT-------VEFRPGETGLNSTRVTISGLDPVTEYKFQVYAENGVSELSPDPANHIE 355
G T V F P + GL +RV + GL Y +V A NGVSELSPDP
Sbjct: 404 GGGGTCHRCRDEVHFDPRQRGLTESRVLVGGLRAHVPYILEVQAVNGVSELSPDPPQAAA 463
Query: 356 ITAVTEAXXXXXXXKLRILNTESDRLTIAWNPPQVDLTDPDDTIESYEVKCFPKDSQDKN 415
I T + ++ S+ +T++W PQ D T + I Y+++ + + ++D++
Sbjct: 464 INVSTSHEVPSAVPVVHQVSRASNSITVSW--PQPDQT--NGNILDYQLRYYDQ-AEDES 518
Query: 416 TNTTLRITKDPQVTITGLRKDTEYGIRVRAKMKRGWGEFSGIVYART 462
+ TL ++ T+T L YG +VRA+ G G + G VY +T
Sbjct: 519 HSFTL-TSETNTATVTQLSPGHIYGFQVRARTAAGHGPYGGKVYFQT 564
>UniRef50_UPI00005A2D48 Cluster: PREDICTED: similar to EPH receptor
A10 isoform 1; n=2; Eutheria|Rep: PREDICTED: similar to
EPH receptor A10 isoform 1 - Canis familiaris
Length = 861
Score = 341 bits (837), Expect = 7e-92
Identities = 173/394 (43%), Positives = 248/394 (62%), Gaps = 12/394 (3%)
Query: 554 RTYIDPHTYEDPNQAVREFAREIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVA 613
RT++DP + DP QAV FAR C+ G FG++ G L+LP E+ VA
Sbjct: 449 RTFLDPQSCGDPLQAVHLFART-PGDCLRCS--FPTGRFGELSFGCLQLPGR--QELPVA 503
Query: 614 IKTLKPGSTERARRDFLAEASIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFL 673
+ TL+ G ++ R FLAEA +GQF+H +V+ L+GV+T+ + +MI+TE+M +G+LD FL
Sbjct: 504 VHTLRDGCSDSQRLSFLAEALTLGQFDHSHVVRLEGVITRGSTLMIVTEYMSHGALDGFL 563
Query: 674 RANDGKFRVLQLVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREI 733
R ++G+ QL+G+L G+A+ M+YLSEM Y+HR LAAR VLV S L+CKI+ FG R
Sbjct: 564 RRHEGQLAAGQLLGLLPGLASAMKYLSEMGYVHRGLAARRVLVTSGLICKISGFG--RGP 621
Query: 734 ESTADGAYTTRGGKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQ 793
A+ YTT G+ P W APE + F F+SASDVWS G+V WEVM+FGERPYW+ S Q
Sbjct: 622 RDRAEAVYTTMSGRSPALWAAPETLQFGHFSSASDVWSFGVVMWEVMAFGERPYWDMSGQ 681
Query: 794 DVIKSIEKGYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLIRCPDTLR-K 852
DVIK++E G+RLP P CP +++LMLDCWQK+ RP FS I L K+++ P+ +
Sbjct: 682 DVIKAVEDGFRLPPPRHCPSLLHRLMLDCWQKDPGERPRFSQIHSILSKMVQDPEPPKCA 741
Query: 853 IAQ--NRSADPLAGDT-PDLIQFTSVEEWLECIKMSRYIEKFRAAGISDMDAVVDLTVHQ 909
IA R PLA F SV WL+ + + RY + F A G ++AV +
Sbjct: 742 IAPLLPRPPTPLADRAFSTFPSFGSVGAWLDALDLGRYKDSFAAGGYGSLEAVAAMAAQD 801
Query: 910 LASLGVTLVGHQKKIMNSVQSMRAQIRG-SGPYG 942
L +LG++ H++ +++ + ++RA++ G SG G
Sbjct: 802 LLNLGISSAEHREALLSGISALRARLLGDSGRSG 835
Score = 99.1 bits (236), Expect = 5e-19
Identities = 55/163 (33%), Positives = 89/163 (54%), Gaps = 6/163 (3%)
Query: 42 VNGNALSCKETFSLLYYEFDVAT-REQPPWEPESYKLVGRIAAGEGRFNTN---SEVDIN 97
+ G A +CKETF++ Y E + R +P + + IAA E + ++ +N
Sbjct: 115 IPGAAGTCKETFNVYYLETEADLGRGRPRPGGSRARKIDTIAADESFTQGDLGERKMKLN 174
Query: 98 TEVKSIA-VTKKGVYFAFRDQGACISILAVKVYYITCPDVNINFARFPATPTGREVTVIE 156
TEV+ + ++++G + AF+D GAC+++++V+VYY C A FPAT + +
Sbjct: 175 TEVREVGPLSRRGFHLAFQDVGACVALVSVRVYYKQCRATVRGLAAFPATAAESAFSTLV 234
Query: 157 QANGTCVANAEVAPGEKAPVYLCKGDGKWTLPSGSCKCRAGFE 199
+ GTCVA++E PG P C DG+W +P G C AGF+
Sbjct: 235 EVTGTCVAHSEGEPG-SPPRMHCGADGEWLVPVGRRSCSAGFQ 276
Score = 35.9 bits (79), Expect = 5.2
Identities = 22/76 (28%), Positives = 39/76 (51%), Gaps = 3/76 (3%)
Query: 370 KLRILNTESDRLTIAWNPPQVDLTDPDDTIESYEVKCFPKDSQDKNTNTTLRITKDPQVT 429
++R E ++++W P V P YE++ + K Q + T +T++ T P VT
Sbjct: 290 EIRRDRVEPQSVSLSWREP-VPAGAPGANGTEYEIRYYEK-GQSEQTYSTVK-TGAPAVT 346
Query: 430 ITGLRKDTEYGIRVRA 445
+T L+ T Y ++RA
Sbjct: 347 VTNLKPATRYVFQIRA 362
>UniRef50_O61460 Cluster: Ephrin receptor 1 precursor; n=3;
Caenorhabditis|Rep: Ephrin receptor 1 precursor -
Caenorhabditis elegans
Length = 1122
Score = 333 bits (819), Expect = 1e-89
Identities = 173/327 (52%), Positives = 216/327 (66%), Gaps = 33/327 (10%)
Query: 554 RTYIDPHTYEDPNQAVREFAREIDASCITIEAIIGGGEFGDVCRGKLKL--PASCG---- 607
+TY+DP TYEDP QA+ EF +I + + I +IGGGEFGDVC G L PA+
Sbjct: 665 KTYVDPTTYEDPYQALIEFTFDISPNDVFITQVIGGGEFGDVCLGGLSKNSPAAAKWSVS 724
Query: 608 ----------------PEIDVAIKTLKPGSTERARRDFLAEASIMGQFEHPNVIFLQGVV 651
P VAIKTLK GS+ +A+ +FL EA+IMGQF HPNVI L GVV
Sbjct: 725 NTTMGRGGGGGGYESEPYETVAIKTLKSGSSAKAKAEFLTEATIMGQFSHPNVIRLIGVV 784
Query: 652 TKCNPIMIITEFMENGSLDTFLRANDGKFRVL---QLVGMLRGIATGMQYLSEMNYIHR- 707
T P+MI+ E+M NGSLD FLR D + + ++ ML GIA+GM+YL++M Y+HR
Sbjct: 785 TSAEPVMIVAEYMANGSLDQFLRNTDQRGEKVHWEKITEMLYGIASGMKYLTDMGYVHRV 844
Query: 708 ----DLAARNVLVNSQLVCKIADFGLSREIES---TADGAYTTRGGKIPVRWTAPEAIAF 760
DLAARNVL++ +L CKIADFGLSR + S + + YTT GGKIPVRWTAPEAI
Sbjct: 845 SFLRDLAARNVLLDMELRCKIADFGLSRGVRSEGSSVEPEYTTNGGKIPVRWTAPEAITH 904
Query: 761 RKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEAVYQLML 820
RKFT +SDVWS G+V WEV SFGERPYW+W+NQ VI + GYRLP PMDCP +Y++
Sbjct: 905 RKFTPSSDVWSFGVVIWEVCSFGERPYWDWTNQKVISEVMIGYRLPPPMDCPMGLYRIAQ 964
Query: 821 DCWQKERTHRPTFSSIVKTLDKLIRCP 847
CW+ ER RPTF+ ++ T K I P
Sbjct: 965 WCWKMERHERPTFTQLLATFHKYILQP 991
Score = 198 bits (482), Expect = 8e-49
Identities = 139/456 (30%), Positives = 220/456 (48%), Gaps = 44/456 (9%)
Query: 45 NALSCKETFSLLYYEFDVAT-------REQPPWEPESYKLVGRIAAGEGRFNTNS-EVDI 96
N SCKETFS+ +F + +E+ + +++K +GR+A T + ++I
Sbjct: 123 NPKSCKETFSVYLKQFKTSRPGSTKIEKERFSEDIDNWKNIGRLARSNSNMTTETLGMEI 182
Query: 97 NTEVKSIAVTKKGVYFAFRDQGACISILAVKVYYITCPDVNINFARFPATPTGREVTVIE 156
+++ K+I + AF +QG C+S+L VK+YY C + F TG + T +
Sbjct: 183 DSDTKTIRI-------AFEEQGICLSLLNVKIYYRICDEFTDQLVYFRPQVTGPKETDMV 235
Query: 157 QANGTCVANA-EVAPGEKAPVYLCKGDGKWTLPSGSCKCRAGFEP--DHNNQICTECAPG 213
+ NG+C+ NA + PG + LC G SG C C +G+ D N C C
Sbjct: 236 RMNGSCIPNASKKIPGVDL-IGLCMSTGSGIKTSGECVCDSGYSQIADSNGARCESCPTN 294
Query: 214 KFKSHTGDEHCIPCPDHSESTIYAAAECKCTPKYYRAKKDPKTIPCTQPPSAPDNLTVTF 273
+K G C CP +S S+ AA+ C+C Y+RA+ + ++PCTQPPS P L
Sbjct: 295 TYKPK-GQSLCKSCPSNSISS-EAASSCRCLNGYFRAEDELISMPCTQPPSRPIKLVANA 352
Query: 274 ADQFSISLTWQPPHNTGGRSDITYKISCA---NCGPTVEFRPGETGLNSTRVTISGLDPV 330
S L+W P + GGR +I Y++ C+ CG TV PG+ L++ V I+GL P
Sbjct: 353 ITATSTRLSWNEPSSLGGRPEIWYEVKCSGRGECG-TVVMTPGDKKLSTRSVQINGLRPS 411
Query: 331 TEYKFQVYAENGVSELSPDPANH---IEITAVTEAXXXXXXXKLRILNTESDRLTIAWNP 387
++Y F V+A+N VS P+ + I+I +E LR+ ++SD +TIAW+
Sbjct: 412 SDYTFLVFAKNKVSAQFPEFSEKNAVIDIRTRSEEEDVPPVSHLRVDASQSDGITIAWSV 471
Query: 388 PQVDLTDPDDTIESYEVKCFPKDSQDKNTNTTLRITKDPQVTITGLRKDTEYGIRVRAKM 447
D++D +EV+ P + + T R T GL +T Y RVR +
Sbjct: 472 SDSDVSD-------FEVEVRPAIVKKRTFET--RHVNMTYTTFIGLNPETVYQFRVRIRD 522
Query: 448 KRGWGEFSGIVYAR-------TNSVTETSFIDEEGA 476
W + R +N V E+ F+++ G+
Sbjct: 523 DLRWSQPISYQLGRGLMSSPSSNEVEESQFLNQTGS 558
>UniRef50_UPI00006A241E Cluster: UPI00006A241E related cluster; n=1;
Xenopus tropicalis|Rep: UPI00006A241E UniRef100 entry -
Xenopus tropicalis
Length = 704
Score = 331 bits (814), Expect = 5e-89
Identities = 181/398 (45%), Positives = 250/398 (62%), Gaps = 17/398 (4%)
Query: 556 YIDPHTYEDPNQAVREF---AREIDASCITIEAIIG-GGEFGDVCRGKLKLPASCGPEID 611
Y D +TY +PN V E A+ + IIG G+FG+VCRG+L LP+ E+
Sbjct: 310 YCDTNTYMEPNDLVGESHTGAQSLGGGIPHWSPIIGPAGDFGEVCRGRLCLPSK--REVA 367
Query: 612 VAIKTLKPGSTERARRDFLAEASIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDT 671
V I+TL+ GS E+ R +FL+EA IMGQF+HPNV+ L+G VT+ PIMI+TE MENG+LD
Sbjct: 368 VCIRTLRTGSGEKERAEFLSEAGIMGQFDHPNVVHLEGAVTRSRPIMILTEHMENGALDA 427
Query: 672 FLRANDGKFRVLQLVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSR 731
FLR +G F LQ+V MLRG+A GM+YLS+ +Y HR+L A NVLVN QLVCK++
Sbjct: 428 FLRQCEGGFSTLQMVSMLRGVAAGMRYLSDRSYNHRNLTAHNVLVNGQLVCKVSGL-RPP 486
Query: 732 EIEST----ADG-AYTTRGGKIPVRWTAPEAIAFRKFTSASDVWSMGIV-CWEVMSFGER 785
E EST +DG A T G + +RW AP+ ++ S + I C V + G R
Sbjct: 487 EQESTIINKSDGKAVMTGGARQSLRWAAPDRCSYMSQQLGSRLVPRCISGCQAVPTLG-R 545
Query: 786 PYWNWSNQDVIKSIEKGYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLIR 845
P + V++++E+ YRLP P DCP A++ LMLDCWQ+ER RP F IV +LD++IR
Sbjct: 546 PRLMLLYEPVLEALEQDYRLPPPPDCPSALHLLMLDCWQRERAQRPRFEQIVSSLDRMIR 605
Query: 846 CPDTLRK--IAQNRSADPLAGD-TPDLIQFTSVEEWLECIKMSRYIEKFRAAGISDMDAV 902
P+ L+ ++ +R + PL + PDL +S EWLE IKM RY E F AG + ++A+
Sbjct: 606 NPNCLKSVGVSSSRPSQPLLSNCPPDLPSLSSPHEWLEAIKMQRYKENFDQAGYTTLEAI 665
Query: 903 VDLTVHQLASLGVTLVGHQKKIMNSVQSMRAQIRGSGP 940
LT + +GVTL GHQKKI+ S+Q ++A ++ P
Sbjct: 666 SRLTAEDIRIIGVTLSGHQKKILGSIQLLKAHLQPLEP 703
Score = 120 bits (289), Expect = 2e-25
Identities = 65/207 (31%), Positives = 96/207 (46%), Gaps = 14/207 (6%)
Query: 210 CAPGKFKSHTGD-EHCIPCPDHSESTIYAAAECKCTPKYYRAKKDPKTIPCTQPPSAPDN 268
C PG ++ C+PCP +S + A C C YYR ++ PCT PPSAP +
Sbjct: 2 CPPGTYRPPDSPISRCLPCPSNSNTITSGALGCVCDKGYYRTPEENPQSPCTGPPSAPWD 61
Query: 269 LTVTFADQFSISLTWQPPHNTGGRSDITYKIS--------CANCGPTVEFRPGETGLNST 320
L ++S +W+ P + GGR ++ Y ++ C CG V FRP + GL T
Sbjct: 62 LNYEVTGPGAVSASWRAPKDLGGRPEVLYSVACKECMGGRCLRCGEGVTFRPSQVGLIHT 121
Query: 321 RVTISGLDPVTEYKFQVYAENGVSELSPDPANHIEITAVTEAXXXXXXXKLRILNTESDR 380
RV +SGL P Y +V A N VSELSP+ H + + L+
Sbjct: 122 RVHLSGLLPGVPYTLEVQAVNQVSELSPEQPKHSSLNLSISQSVPSAVPIMHQLHRSKQS 181
Query: 381 LTIAWNPPQVDLTDPDDTIESYEVKCF 407
+T+ W P+ P+ I Y++ C+
Sbjct: 182 ITLTWPEPE----QPNGKILDYQL-CY 203
>UniRef50_UPI000065CB69 Cluster: Homolog of Homo sapiens "Ephrin
type-A receptor 4 precursor; n=1; Takifugu rubripes|Rep:
Homolog of Homo sapiens "Ephrin type-A receptor 4
precursor - Takifugu rubripes
Length = 1039
Score = 330 bits (812), Expect = 8e-89
Identities = 176/389 (45%), Positives = 245/389 (62%), Gaps = 14/389 (3%)
Query: 551 TGSRTYIDPHTYEDPNQAVREFAREIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEI 610
+G +TY+DP TYEDP QAV EF +EID+SCI I+ +IG GEFG+VCRG+L P +I
Sbjct: 661 SGIKTYVDPDTYEDPTQAVEEFTKEIDSSCIGIDRVIGAGEFGEVCRGRLHTPGRM--DI 718
Query: 611 DVAIKTLKPGSTERARRDFLAEASIMGQFEHPNVIFLQGVVT--KCNPIMIITEFMENGS 668
VAIKTL+ G E+ RR+FL EASI+GQF N+I L+GVVT K +T + G
Sbjct: 719 TVAIKTLRAGQGEQQRREFLREASILGQFSSSNIIRLEGVVTKSKLKDRRRMTYLSDMGY 778
Query: 669 LDTFLRANDGKFRVLQLVGMLRGIAT-GMQYLSEMNYIHRDLAARNVLVNSQLVCKIADF 727
+ L A + +L + ++ GM + E + V + +
Sbjct: 779 IHRDLAARN----ILVDENLACKVSDFGMSRVLEDE--GEEAYTATVSIGQLHPHILMAS 832
Query: 728 GLSREIESTADG-AYTTRGGKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERP 786
G + T D +GGKIP+RWTAPE+IA+ KF++ASDVWS GIV WEVMS+GERP
Sbjct: 833 GQPTGLFLTTDHLCVPCQGGKIPIRWTAPESIAYGKFSTASDVWSYGIVMWEVMSYGERP 892
Query: 787 YWNWSNQDVIKSIEKGYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLIRC 846
YW SNQDVI SIE+GYRLPAP+ CP ++QLML WQKE + RP FS+++ LDKLI
Sbjct: 893 YWEMSNQDVILSIEEGYRLPAPVGCPVTLHQLMLHSWQKEASQRPRFSNVLSFLDKLIVN 952
Query: 847 PDTLRKIAQNRSADPLAGDTPDLIQFTSVEEWLECIKMSRYIEKFRAAGISDMDAVVDLT 906
P +L + Q+ S P D PD F S+ +WL+ IKM +Y F AAG + +D++ ++
Sbjct: 953 PSSLMEDVQSFSESP--DDLPDYPLFISIGDWLDSIKMCQYKNNFLAAGYTTLDSISTMS 1010
Query: 907 VHQLASLGVTLVGHQKKIMNSVQSMRAQI 935
+ + +G+ L+GHQ++I++S+QS+R Q+
Sbjct: 1011 MDDIRRIGICLLGHQRRIISSIQSLRLQL 1039
Score = 111 bits (267), Expect = 9e-23
Identities = 75/225 (33%), Positives = 99/225 (44%), Gaps = 30/225 (13%)
Query: 210 CAPGKFKSHTGDEHCIPCPDHSESTIYAAAECKCTPKYYRAKKDPKTIPCTQ-------- 261
C PG FK++ G+ C CP HS S A C C +YRA +D T CT
Sbjct: 290 CKPGFFKAYAGNHKCSICPLHSSSHDQAGTICHCEKGFYRAIQDSSTTACTTITMLHLFS 349
Query: 262 --PPSAPDNLTVTFADQFSISLTWQPPHNTGGRSDITYKISCANCG-------------- 305
PPSAP NL V+ + ++ L W PPH++GGR DITY I C C
Sbjct: 350 SGPPSAPRNL-VSLINDTALILQWMPPHDSGGRKDITYNIFCQRCDGSADISGIIQCEPC 408
Query: 306 -PTVEFRPGETGLNSTRVTISGLDPVTEYKFQVYAENGVSELSPDPANHIEITAVTEAXX 364
P + F P GL T V I Y F V A NGVS L + +T T
Sbjct: 409 EPDLRFIPRPLGLTGTSVAILDFAMHVSYTFHVEAVNGVSALGVAARPLVNVTVNTHHAG 468
Query: 365 XXXXXKLRILNTESDRLTIAWNPPQVDLTDPDDTIESYEVKCFPK 409
++R + + + ++W+ QV+ P I YEVK + K
Sbjct: 469 PALVGEVRKDSASHNSIALSWS--QVE--QPPSNIVDYEVKYYEK 509
Score = 97.1 bits (231), Expect = 2e-18
Identities = 63/160 (39%), Positives = 84/160 (52%), Gaps = 14/160 (8%)
Query: 48 SCKETFSLLYYEFD----VATREQPPWEPESYKLVGRIAAGEGRFNTN---SEVDINTEV 100
+CKETF+L Y + D TR +K V IAA E T+ + +NTEV
Sbjct: 64 TCKETFNLFYLQRDEPLPAGTRACTNDGFFGFK-VDTIAADESFTQTDLGDRVLRLNTEV 122
Query: 101 KSIA-VTKKGVYFAFRDQGACISILAVKVYYITCPDVNINFARFPATPTGREVTVIEQAN 159
+ + VT+KG Y AF+D GACI++++VKV+Y CP N A FP T + V +
Sbjct: 123 REVGPVTQKGFYLAFQDVGACIALVSVKVFYKRCPPTVRNLAAFPDTVPHMDSLV--EVR 180
Query: 160 GTCVANAEVAPGEKAPVYLCKGDGKWTLPSGSCKCRAGFE 199
G+CV NAE + P C DG W +P G C C AG E
Sbjct: 181 GSCVENAE---ERETPKLYCGADGDWLVPLGRCVCSAGHE 217
>UniRef50_Q4SFK0 Cluster: Chromosome 7 SCAF14601, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 7
SCAF14601, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 993
Score = 314 bits (770), Expect = 1e-83
Identities = 151/251 (60%), Positives = 191/251 (76%), Gaps = 6/251 (2%)
Query: 687 GMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREI-ESTADGAYTTR- 744
G +RGIA+GM+YLSEM+Y+HRDLAARN+L+NS LVCK++DFGLSR + E+++D YT+
Sbjct: 731 GDVRGIASGMKYLSEMSYVHRDLAARNILINSNLVCKVSDFGLSRFLQENSSDPTYTSSL 790
Query: 745 GGKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYR 804
GGKIP+RWTAPEAIAFRKFTSASDVWS GIV WEVMSFGERPYW+ SNQDVI +IE+ YR
Sbjct: 791 GGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQDYR 850
Query: 805 LPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLIRCPDTLRKIAQN--RSADPL 862
LP P DCP ++QLMLDCWQK+R+ RP F+ +V LDKLIR P +L+ +AQ+ + PL
Sbjct: 851 LPPPPDCPTHLHQLMLDCWQKDRSARPRFADLVSALDKLIRNPASLKIVAQDGVGPSYPL 910
Query: 863 AGDTPDLI--QFTSVEEWLECIKMSRYIEKFRAAGISDMDAVVDLTVHQLASLGVTLVGH 920
L SV EWL IKM RY + F AG+S +D + ++ L +GVTL GH
Sbjct: 911 LDQRAPLALSGCASVGEWLRTIKMERYEDSFLQAGLSTVDQLSQISTQDLLHMGVTLAGH 970
Query: 921 QKKIMNSVQSM 931
Q+KI++S+QSM
Sbjct: 971 QRKILSSIQSM 981
Score = 176 bits (428), Expect = 3e-42
Identities = 81/125 (64%), Positives = 101/125 (80%), Gaps = 2/125 (1%)
Query: 552 GSRTYIDPHTYEDPNQAVREFAREIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEID 611
G + YIDP TYEDPN+AVREFA+EID S + IE +IG GEFG+VCRG+LK+P E
Sbjct: 570 GVKVYIDPFTYEDPNEAVREFAKEIDVSFVKIEEVIGAGEFGEVCRGRLKIPGK--KENY 627
Query: 612 VAIKTLKPGSTERARRDFLAEASIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDT 671
V IKTLK G T++ RRDFL+EASIMGQF+HPN+I L+GV+T P+MI+TEFMENG+LD+
Sbjct: 628 VPIKTLKGGYTDKQRRDFLSEASIMGQFQHPNIIHLEGVITASCPVMILTEFMENGALDS 687
Query: 672 FLRAN 676
FLR +
Sbjct: 688 FLRVS 692
Score = 105 bits (251), Expect = 7e-21
Identities = 74/241 (30%), Positives = 118/241 (48%), Gaps = 23/241 (9%)
Query: 227 CPDHSESTIYAAAECKCTPKYYRAKKDPKTIPCTQPPSAPDNLTVTFADQFSISLTWQPP 286
C + + C C P + A+ + C +PPSAP ++ VT + ++ L W P
Sbjct: 222 CGEDGQWVGQPTTSCACLPGFEPAEGQKR---CREPPSAPRSI-VTQMNDSTLGLEWNEP 277
Query: 287 HNTGGRSDITYKISCA----------NCGPTVEFRPGETGLNSTRVTISGLDPVTEYKFQ 336
+GGR+D++Y I C +CG +V +RP + GL RV + GL P Y F
Sbjct: 278 LESGGRTDLSYSIRCTVCRAAGAPCLSCGDSVSYRPTQYGLVERRVEVWGLLPQATYIFT 337
Query: 337 VYAENGVSEL-SPDPAN-HIEITAVTEAXXXXXXXKLRILNTESDRLTIAWNPPQVDLTD 394
+ A NGVS+L S +PA+ + IT + + RI +TES LT+ W+ P
Sbjct: 338 IQALNGVSQLSSKEPASKSVNITTTHDVPSLVSLIQ-RIDSTESS-LTLHWSVPD----H 391
Query: 395 PDDTIESYEVKCFPKDSQDKNTNTTLRITKDPQVTITGLRKDTEYGIRVRAKMKRGWGEF 454
P TI Y+++ K+ + ++ ++ Q +T LR+ T Y ++VR G+G F
Sbjct: 392 PRYTILRYQIRYCEKERRSEDQCHHTESNRN-QAVLTDLRRATPYEVQVRVHTAAGYGSF 450
Query: 455 S 455
S
Sbjct: 451 S 451
Score = 102 bits (244), Expect = 5e-20
Identities = 58/167 (34%), Positives = 87/167 (52%), Gaps = 9/167 (5%)
Query: 48 SCKETFSLLYYEFDV--ATREQPPWEPESYKLVGRIAAGEGRFNTNSEVDINTEVKSIA- 104
SCKETF+L YY+ D AT PPW Y V +AA + E N + +
Sbjct: 91 SCKETFNLYYYQTDSDDATSAYPPWMENPYTKVDTVAA-DFLLREGGEKKFNMKTFKLGP 149
Query: 105 VTKKGVYFAFRDQGACISILAVKVYYITCPDVNINFARFPATPTGREVTVIEQANGTCVA 164
++K+G Y AF+ QG C+++L+V+V++ CP + + FP T T++++A G CV
Sbjct: 150 LSKRGFYLAFQAQGTCMALLSVRVFFKKCPALVSALSSFPETVPR---TLVQEAQGVCVE 206
Query: 165 NA-EVAPGEKAPVYLCKGDGKWT-LPSGSCKCRAGFEPDHNNQICTE 209
+A + + P C DG+W P+ SC C GFEP + C E
Sbjct: 207 HATQHGLRPRPPKLFCGEDGQWVGQPTTSCACLPGFEPAEGQKRCRE 253
>UniRef50_Q4RVA1 Cluster: Chromosome 15 SCAF14992, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 15 SCAF14992, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 885
Score = 310 bits (760), Expect = 2e-82
Identities = 173/376 (46%), Positives = 236/376 (62%), Gaps = 16/376 (4%)
Query: 374 LNTESDRLTIAWNPPQVDLTDPDDTIESYEVKCFPKDSQDKNTNTTLRITKDPQVTITGL 433
+++ + T++W P+ P+ I YE++ + KD ++ N+ T LR ++ + L
Sbjct: 223 ISSTMNSFTLSWPQPE----QPNGIILDYELRYYEKDHEEINS-TVLR-SQTNTARVEAL 276
Query: 434 RKDTEYGIRVRAKMKRGWGEFSGIVYARTNSVTETSFIDEEGAQXXXXXXXXXXXXXXXX 493
R T Y ++VRA+ G+G++S + +T +T+ F E Q
Sbjct: 277 RPGTVYVVQVRARTVAGFGKYSSKMCFQT--LTDDDFKSELREQLPLIAGSAAAGVVFIV 334
Query: 494 XXXXXXXXFLRSRADDECDKKQPSDCNALNYRNG-EVYTGPDRPAKTSSNATTPLFAGT- 551
R RA K+ +Y G E+ D +S F+G+
Sbjct: 335 SLVAISIICSRKRA---YSKEAVYSDKLQHYSTGRELSLRADMSNCSSPLGCPTHFSGSP 391
Query: 552 GSRTYIDPHTYEDPNQAVREFAREIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEID 611
G + YIDP TYEDPN+AVREFA+EID S + IE +IG GEFG+V +G+LKLP EI
Sbjct: 392 GMKIYIDPFTYEDPNEAVREFAKEIDVSTVKIEEVIGAGEFGEVYKGRLKLPGK--REIY 449
Query: 612 VAIKTLKPGSTERARRDFLAEASIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDT 671
VAIKTLK G E+ RRDFL+EASIMGQF+HPN+I L+GVVTK P+MI+TEFMENG+LD+
Sbjct: 450 VAIKTLKSGYVEKQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIVTEFMENGALDS 509
Query: 672 FLRANDGKFRVLQLVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSR 731
FLR NDG+F V+QLVGM+RGI+ GM+YLSEMNY+HRDLAARN+LVNS LVCK++DFGLSR
Sbjct: 510 FLRQNDGQFTVIQLVGMMRGISAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSR 569
Query: 732 EI-ESTADGAYTTRGG 746
+ E T+D +YT+ G
Sbjct: 570 YLQEDTSDPSYTSSLG 585
Score = 257 bits (630), Expect = 9e-67
Identities = 122/199 (61%), Positives = 148/199 (74%), Gaps = 3/199 (1%)
Query: 743 TRGGKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKG 802
T+GGKIPVRWTAPEAIA+RKFTSASDVWS GIV WEVMSFGERPYW+ SNQDVI +IE+
Sbjct: 682 TKGGKIPVRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQD 741
Query: 803 YRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLIRCPDTLRKIAQNRS--AD 860
YRLP PMDCP ++QLMLDCWQK+R RP F+ IV TLDK+IR P +L+ IA S +
Sbjct: 742 YRLPPPMDCPSTLHQLMLDCWQKDRNVRPRFADIVSTLDKMIRNPTSLKAIANIPSVPSQ 801
Query: 861 PLAG-DTPDLIQFTSVEEWLECIKMSRYIEKFRAAGISDMDAVVDLTVHQLASLGVTLVG 919
PL PD F+SVE+WL IKMS+Y + F +G + + V +T L +GVTL G
Sbjct: 802 PLLDRSIPDFNTFSSVEDWLGAIKMSQYRDNFLNSGFTSLQLVAQMTSEDLLRIGVTLAG 861
Query: 920 HQKKIMNSVQSMRAQIRGS 938
HQKKI+++VQSMR Q+ S
Sbjct: 862 HQKKILSNVQSMRVQMSQS 880
Score = 131 bits (316), Expect = 1e-28
Identities = 67/161 (41%), Positives = 86/161 (53%), Gaps = 11/161 (6%)
Query: 210 CAPGKFKSHTGDEHCIPCPDHSESTIYAAAECKCTPKYYRAKKDPKTIPCTQPPSAPDNL 269
C PG FKS G C+ CP +S ST AA C C YYR D PCT PS+P N+
Sbjct: 22 CPPGTFKSTQGPGLCLQCPPNSRSTAEAATVCVCRNGYYRGDADQPDEPCTSVPSSPRNV 81
Query: 270 TVTFADQFSISLTWQPPHNTGGRSDITYKI----------SCANCGPTVEFRPGETGLNS 319
++ ++ S+ L W PP TGGR D+ Y I +C++C V+F P + GL
Sbjct: 82 -ISVVNETSVILEWHPPRETGGRGDVVYNIVCKKCRADRRACSHCEDNVDFVPRQLGLTE 140
Query: 320 TRVTISGLDPVTEYKFQVYAENGVSELSPDPANHIEITAVT 360
+RV IS L T Y F++ A NGVS SP PA H+ I T
Sbjct: 141 SRVLISNLLAHTLYSFEIQAVNGVSNKSPYPAQHVSIDITT 181
>UniRef50_Q96HF4 Cluster: EPHA2 protein; n=3; Amniota|Rep: EPHA2
protein - Homo sapiens (Human)
Length = 253
Score = 308 bits (757), Expect = 4e-82
Identities = 141/250 (56%), Positives = 182/250 (72%), Gaps = 3/250 (1%)
Query: 693 ATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGGKIPVRW 752
A GM+YL+ MNY+HRDLAARN+LVNS LVCK++DFGLSR +E + YTT GGKIP+RW
Sbjct: 1 AAGMKYLANMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEATYTTSGGKIPIRW 60
Query: 753 TAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCP 812
TAPEAI++RKFTSASDVWS GIV WEVM++GERPYW SN +V+K+I G+RLP PMDCP
Sbjct: 61 TAPEAISYRKFTSASDVWSFGIVMWEVMTYGERPYWELSNHEVMKAINDGFRLPTPMDCP 120
Query: 813 EAVYQLMLDCWQKERTHRPTFSSIVKTLDKLIRCPDTLRKIA--QNRSADPLAGDT-PDL 869
A+YQLM+ CWQ+ER RP F+ IV LDKLIR PD+L+ +A R + L + +
Sbjct: 121 SAIYQLMMQCWQQERARRPKFADIVSILDKLIRAPDSLKTLADFDPRVSIRLPSTSGSEG 180
Query: 870 IQFTSVEEWLECIKMSRYIEKFRAAGISDMDAVVDLTVHQLASLGVTLVGHQKKIMNSVQ 929
+ F +V EWLE IKM +Y E F AAG + ++ VV +T + +GV L GHQK+I S+
Sbjct: 181 VPFRTVSEWLESIKMQQYTEHFMAAGYTAIEKVVQMTNDDIKRIGVRLPGHQKRIAYSLL 240
Query: 930 SMRAQIRGSG 939
++ Q+ G
Sbjct: 241 GLKDQVNTVG 250
>UniRef50_UPI000155CF4D Cluster: PREDICTED: similar to EPH receptor
A10; n=1; Ornithorhynchus anatinus|Rep: PREDICTED:
similar to EPH receptor A10 - Ornithorhynchus anatinus
Length = 578
Score = 303 bits (743), Expect = 2e-80
Identities = 168/399 (42%), Positives = 234/399 (58%), Gaps = 36/399 (9%)
Query: 554 RTYIDPHTYEDPNQAVREFAREIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVA 613
RTY+DP + EDP QAV FA+E+D S I IE +IG G G + PA G
Sbjct: 189 RTYVDPESCEDPLQAVHLFAKELDNSSIKIERVIGTGN-GPPRHRRGSNPAGFGM----- 242
Query: 614 IKTLKPGSTERAR-RDFLAEASIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTF 672
R R FL G + G + + + +M +TEFM NG+LD+F
Sbjct: 243 ----------RGRGNSFLRSQGRSGSLTISELPNGSGSLER-STLMTVTEFMGNGALDSF 291
Query: 673 LRANDGKFRVLQLVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSRE 732
LR ++G+ +L+G+L G+A+GMQYLSEM Y+HR LAAR VLV+ LVCKI+ G R
Sbjct: 292 LRKHEGQLSSGELMGLLPGVASGMQYLSEMGYVHRSLAARCVLVSHSLVCKIS--GFRRN 349
Query: 733 IESTADGAYTTRGGKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSN 792
++ A+ ++T G+ P W APEA+ F+SASDVWS G+V WEVMSFGERPYW+ S+
Sbjct: 350 VDDKAETVFSTLSGRSPALWAAPEAVQLGHFSSASDVWSFGVVMWEVMSFGERPYWDMSS 409
Query: 793 QDVIKSIEKGYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLIRCPD---- 848
QDV+K+IE G+RLPAP CP ++QLMLDCWQ++ RP F I L K+ + PD
Sbjct: 410 QDVVKAIEDGFRLPAPRTCPGPLHQLMLDCWQRDPNERPKFLQIYALLSKMAKIPDPPTS 469
Query: 849 ----TLRKIAQNRSADPLAGDTPDLIQ--------FTSVEEWLECIKMSRYIEKFRAAGI 896
R A A + G + L F+SV EWLE I++ RY + F AAG
Sbjct: 470 NAAPCPRPHAPGSPAPRVPGPSLSLADHPFSAFPCFSSVGEWLEAIELERYKDNFAAAGY 529
Query: 897 SDMDAVVDLTVHQLASLGVTLVGHQKKIMNSVQSMRAQI 935
++ V LT+ +A+LG+T + HQ++++ +Q++R Q+
Sbjct: 530 RSLEFVARLTIQDVANLGITTMEHQRQLLAGIQALRTQM 568
>UniRef50_UPI000065F2B9 Cluster: Ephrin type-A receptor 8 precursor
(EC 2.7.10.1) (Tyrosine-protein kinase receptor EEK)
(EPH- and ELK-related kinase) (HEK3).; n=1; Takifugu
rubripes|Rep: Ephrin type-A receptor 8 precursor (EC
2.7.10.1) (Tyrosine-protein kinase receptor EEK) (EPH-
and ELK-related kinase) (HEK3). - Takifugu rubripes
Length = 957
Score = 273 bits (670), Expect = 1e-71
Identities = 150/295 (50%), Positives = 188/295 (63%), Gaps = 15/295 (5%)
Query: 656 PIMIITEFMENGSLDTFLRA-ND---GKFRVLQLV----GMLRGIATG-MQYLSEMNYIH 706
P+MIITE+MENGSLD+FLR ND K+ + L +L+ T + L +N +
Sbjct: 661 PVMIITEYMENGSLDSFLRVRNDLMLHKYVFICLTFNNPHLLQSDDTSDISPLHSLNLLS 720
Query: 707 RDLAARNVLVNSQLVCKIADFGLSREI--ESTADGAYTT----RGGKIPVRWTAPEAIAF 760
R R L A G R E++ DG T+ +GGKIP+RWTAPEAIAF
Sbjct: 721 RVSERRPEWRGEALQTVPALSGPQRRTLHENSRDGIRTSACLRQGGKIPIRWTAPEAIAF 780
Query: 761 RKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEAVYQLML 820
RKF+S+SDVWS G+V WEV S+GERPYWN +N+DVIKS+E+GYRLPAPM CP A++ LML
Sbjct: 781 RKFSSSSDVWSYGVVMWEVTSYGERPYWNLTNRDVIKSVEEGYRLPAPMGCPAALHTLML 840
Query: 821 DCWQKERTHRPTFSSIVKTLDKLIRCPDTLRKIAQNRSADPLAGDTPDLIQFTSVEEWLE 880
DCWQK+R RP F IV LDKLIR P+ L+ + RS + PDL SV EWL+
Sbjct: 841 DCWQKDRNERPRFCQIVTVLDKLIRNPENLKSMDTLRSPPLMERAMPDLSSCNSVNEWLD 900
Query: 881 CIKMSRYIEKFRAAGISDMDAVVDLTVHQLASLGVTLVGHQKKIMNSVQSMRAQI 935
IKMSRY + F A G + V+ + + LGVTL+GHQKKIM SVQ MRAQ+
Sbjct: 901 TIKMSRYKDHFAAGGYHTLGHVIGMNQGDIQRLGVTLMGHQKKIMTSVQMMRAQV 955
Score = 145 bits (352), Expect = 4e-33
Identities = 72/109 (66%), Positives = 86/109 (78%), Gaps = 2/109 (1%)
Query: 553 SRTYIDPHTYEDPNQAVREFAREIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDV 612
+R YIDPHTYEDP QAV EFAREI+AS I IE IIG GEFG+VC G+++LP +I V
Sbjct: 532 ARFYIDPHTYEDPCQAVHEFAREIEASRIKIEKIIGSGEFGEVCYGRMRLPGK--RDIPV 589
Query: 613 AIKTLKPGSTERARRDFLAEASIMGQFEHPNVIFLQGVVTKCNPIMIIT 661
A+KTLK G TE+ +RDFLAEASIM QF+HPNVI L+GVVT+ I I+T
Sbjct: 590 ALKTLKVGYTEKQKRDFLAEASIMAQFDHPNVIRLEGVVTQSTLIRILT 638
Score = 105 bits (252), Expect = 6e-21
Identities = 61/170 (35%), Positives = 88/170 (51%), Gaps = 10/170 (5%)
Query: 48 SCKETFSLLYYEFDVATREQPPWEPESYKLVGRIAAGEGRFNTNSEV---DINTEVKSIA 104
+CKETF+L YYE D A + + IAA E + V +NTEV+ +
Sbjct: 65 TCKETFNLYYYESDRAVGSTV--RENQFIKIDTIAADESFTGVDLGVRRLKLNTEVRGVG 122
Query: 105 -VTKKGVYFAFRDQGACISILAVKVYYITCPDVNINFARFPATPTGREVTVIEQANGTCV 163
+TK+G Y AF+D GACI++ +V+VYY C V+ N A F TG + + + + G CV
Sbjct: 123 PLTKRGFYLAFQDIGACIALTSVRVYYKRCVGVSRNLAVFTDVVTGADSSSLVEVRGQCV 182
Query: 164 ANAEVAPGEKAPVYLCKGDGKWTLPSGSCKCRAGFEPDHNNQICTECAPG 213
+AE P C +G+W +P G C C AGFE +H + + G
Sbjct: 183 DHAE---ERDTPKMYCSAEGEWLVPIGRCVCSAGFE-EHRDSCVSRSGTG 228
Score = 54.0 bits (124), Expect = 2e-05
Identities = 43/170 (25%), Positives = 75/170 (44%), Gaps = 20/170 (11%)
Query: 308 VEFRPGETGLNSTRVTISGLDPVTEYKFQVYAENGVSELSPDPANHIEITAVTEAXXXXX 367
+ F P ++GL VT+ L + Y F++ A N V+ S +P+ + T
Sbjct: 327 IRFIPRQSGLTEPWVTVLNLVAHSNYSFRILATNAVTLQSNEPSLYAIANITTNQAAPSE 386
Query: 368 XXKLRILNTESDRLTIAWNPPQVDLTDPDDTIESYEVKCFPK-------------DSQDK 414
+R N + +T+ W+ P P+ I Y++K + K +S D
Sbjct: 387 VLAVRQENASQNSVTLQWHEPD----QPNGVILEYDIKYYEKVWTPLEPRAKQEAESLDN 442
Query: 415 NTN--TTLRITKDPQVTITGLRKDTEYGIRVRAKMKRGWGEFSGIVYART 462
+ +TL+ +K+ + GL+ T+Y +VRA+ G G FS V +T
Sbjct: 443 EEHIYSTLK-SKNTTARVLGLKPGTKYIFQVRARTSAGCGRFSQNVEIQT 491
>UniRef50_Q4TFI7 Cluster: Chromosome undetermined SCAF4439, whole
genome shotgun sequence; n=3; Tetraodontidae|Rep:
Chromosome undetermined SCAF4439, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 179
Score = 268 bits (657), Expect = 5e-70
Identities = 122/177 (68%), Positives = 147/177 (83%), Gaps = 2/177 (1%)
Query: 673 LRANDGKFRVLQLVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSRE 732
L+ NDG+F + QLVGMLRG+A M+YLS+MNY+HRDLAARN+LVNS LVCK++DFGLSR
Sbjct: 1 LQLNDGRFTMTQLVGMLRGVAGVMKYLSDMNYVHRDLAARNILVNSNLVCKVSDFGLSRF 60
Query: 733 IEST-ADGAYTTR-GGKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNW 790
++ T AD YT+ GGKIP+RWTAPEAIAFRKFT+ASDVWS GIV WEV+S+GERPYW+
Sbjct: 61 LDDTSADPTYTSSLGGKIPIRWTAPEAIAFRKFTTASDVWSYGIVMWEVVSYGERPYWDM 120
Query: 791 SNQDVIKSIEKGYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLIRCP 847
SNQDV+ ++E+ YRLP PMDCP ++QLML+CW KER RP FS IV TLDKL P
Sbjct: 121 SNQDVMTAVEQDYRLPPPMDCPMVLHQLMLECWMKERNLRPKFSRIVGTLDKLCATP 177
>UniRef50_Q4SI07 Cluster: Ephrin receptor; n=8; Clupeocephala|Rep:
Ephrin receptor - Tetraodon nigroviridis (Green puffer)
Length = 912
Score = 260 bits (636), Expect = 2e-67
Identities = 129/283 (45%), Positives = 183/283 (64%), Gaps = 32/283 (11%)
Query: 678 GKFRVLQLVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTA 737
G+F ++ L G+ T M YIHRDLAARN+LV+ L+CK++DFG+SR +E +
Sbjct: 633 GQFNNTNII-RLEGVVT-----KNMGYIHRDLAARNILVDENLLCKVSDFGMSRVLEDDS 686
Query: 738 DGAYTTRGGKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQD--- 794
+ AYT GGKIP+RWTAPE+IA+ KF++ASDVWS GIV WEVMS+GERPYW SNQD
Sbjct: 687 EEAYTATGGKIPIRWTAPESIAYGKFSTASDVWSYGIVMWEVMSYGERPYWEMSNQDVSS 746
Query: 795 ----------------------VIKSIEKGYRLPAPMDCPEAVYQLMLDCWQKERTHRPT 832
V+ SIE+GYRLPAP+ CP ++QLML CWQKE + RP
Sbjct: 747 RPSNSIQNEASCVFHLVCVSAQVVLSIEEGYRLPAPVGCPVTLHQLMLHCWQKEASQRPR 806
Query: 833 FSSIVKTLDKLIRCPDTLRKIAQNRSADPLAGDTPDLIQFTSVEEWLECIKMSRYIEKFR 892
FS+++ LDKLI P +L Q+ + + PD F S+ +WL+ IKM +Y F
Sbjct: 807 FSNVLSFLDKLIVNPSSLVDDEQSSFCES-PDELPDYPLFISIGDWLDSIKMCQYKNNFL 865
Query: 893 AAGISDMDAVVDLTVHQLASLGVTLVGHQKKIMNSVQSMRAQI 935
AAG + +D++ +++ + +G+ L+GHQ++I++S+QS+R Q+
Sbjct: 866 AAGYTTLDSISTMSIDDIRRIGICLLGHQRRILSSIQSLRLQL 908
Score = 245 bits (600), Expect = 4e-63
Identities = 151/427 (35%), Positives = 211/427 (49%), Gaps = 33/427 (7%)
Query: 48 SCKETFSLLYYEFDVATREQPPWEPESYKLVGRIAAGEGRFNTN---SEVDINTEVKSIA 104
+CKETF+L Y + D + P Y V IAA E T+ + +NTEV+ +
Sbjct: 64 TCKETFNLFYLQRDEPLPLSTRFRPTDYAKVDTIAADESFTQTDLGDRVLRLNTEVREVG 123
Query: 105 -VTKKGVYFAFRDQGACISILAVKVYYITCPDVNINFARFPATPTGREVTVIEQANGTCV 163
VT+KG Y AF+D GACI++++VKV+Y CP + N A FP T + V + G+CV
Sbjct: 124 PVTQKGFYLAFQDVGACIALVSVKVFYKRCPPIVRNLAAFPDTVPHMDSLV--EVRGSCV 181
Query: 164 ANAEVAPGEKAPVYLCKGDGKWTLPSGSCKCRAGFEPDHNNQICTECAPGKFKSHTGDEH 223
E + + P C DG W +P G C C AG E ++ C C PG FK++ G+
Sbjct: 182 ---EYSEERETPKLYCGADGDWLVPLGRCVCSAGHE--ESDGYCEACKPGFFKAYAGNHK 236
Query: 224 CIPCPDHSESTIYAAAECKCTPKYYRAKKDPKTIPCTQPPSAPDNLTVTFADQFSISLTW 283
C CP HS S AA C C +YRA +D T CT+PPSAP NL V+ + ++ L W
Sbjct: 237 CSICPLHSSSHDQAATICHCDKGFYRAIQDSSTTSCTRPPSAPRNL-VSLINDTALILQW 295
Query: 284 QPPHNTGGRSDITYKISCANCG---------------PTVEFRPGETGLNSTRVTISGLD 328
PPH++GGR DITY + C C P + F P GL T V I
Sbjct: 296 MPPHDSGGRKDITYNVFCQRCDESAGVSSTTQCEPCEPDLRFIPRPLGLTGTSVAILDFA 355
Query: 329 PVTEYKFQVYAENGVSELSPDPANHIEITAVTEAXXXXXXXKLRILNTESDRLTIAWNPP 388
Y F V A NGVS L + +T T ++R + + + ++W+
Sbjct: 356 MHASYTFHVEAVNGVSLLGVAARPLVNVTVNTHHAGPALVGEVRKDSASHNSIALSWS-- 413
Query: 389 QVDLTDPDDTIESYEVKCFPKDSQDKNTNTTLRITKDPQVTITGLRKDTEYGIRVRAKMK 448
+ P I YEVK + K +Q++ + +++R TK P V ITGLR T Y VR
Sbjct: 414 --RVEQPPSNIVDYEVKYYEK-AQERLSYSSIR-TKTPSVVITGLRPSTVYVFHVRVHTA 469
Query: 449 RGWGEFS 455
G+ +S
Sbjct: 470 DGYTTYS 476
Score = 131 bits (317), Expect = 7e-29
Identities = 60/103 (58%), Positives = 81/103 (78%), Gaps = 2/103 (1%)
Query: 551 TGSRTYIDPHTYEDPNQAVREFAREIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEI 610
+G +TY+DP TYEDP QAV EFA+EID+S I+I+ +IG GEFG+VCRG+L +P +I
Sbjct: 549 SGIKTYVDPDTYEDPTQAVEEFAKEIDSSYISIDRVIGAGEFGEVCRGRLHMPGRM--DI 606
Query: 611 DVAIKTLKPGSTERARRDFLAEASIMGQFEHPNVIFLQGVVTK 653
VAIKTL+ G E+ +R+FL EAS++GQF + N+I L+GVVTK
Sbjct: 607 TVAIKTLRAGQREQQKREFLREASVIGQFNNTNIIRLEGVVTK 649
>UniRef50_P42686 Cluster: Tyrosine-protein kinase isoform SRK1;
n=11; Metazoa|Rep: Tyrosine-protein kinase isoform SRK1
- Spongilla lacustris (Freshwater sponge)
Length = 505
Score = 243 bits (595), Expect = 2e-62
Identities = 118/268 (44%), Positives = 173/268 (64%), Gaps = 10/268 (3%)
Query: 575 EIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEAS 634
EI+ + I + +G G+FG+V G S VA+KTLKPG+ + +FL EAS
Sbjct: 234 EIEKTQIKLLRRLGAGQFGEVWEGLWNGTTS------VAVKTLKPGTM--SVEEFLQEAS 285
Query: 635 IMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFRVLQLVGMLRGIAT 694
IM + HP +I L V TK PI I+TE M+ GSL +LR DG ++ QLV + +A+
Sbjct: 286 IMKRLRHPKLIQLYAVCTKEEPIYIVTELMKYGSLLEYLRGEDGVLKIEQLVDVAAQVAS 345
Query: 695 GMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGGKIPVRWTA 754
GM YL + NYIHRDLAARN+LV +CK+ADFGL+R I+ A+T G K P++WTA
Sbjct: 346 GMSYLEQQNYIHRDLAARNILVGEHGICKVADFGLARVIDEEIYEAHT--GAKFPIKWTA 403
Query: 755 PEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEA 814
PEA + +FT SDVWS G+V +E++++G PY +N +V++ I++ YR+P P +CP+
Sbjct: 404 PEAAMYNRFTIKSDVWSFGVVLYEIITYGRFPYPGMTNPEVLEKIQQNYRMPCPANCPKQ 463
Query: 815 VYQLMLDCWQKERTHRPTFSSIVKTLDK 842
+ +MLDCW+++ RPTF ++ L++
Sbjct: 464 FHDIMLDCWREDPASRPTFETLQWQLEE 491
>UniRef50_P08631 Cluster: Tyrosine-protein kinase HCK; n=32;
Euteleostomi|Rep: Tyrosine-protein kinase HCK - Homo
sapiens (Human)
Length = 526
Score = 241 bits (590), Expect = 6e-62
Identities = 127/279 (45%), Positives = 175/279 (62%), Gaps = 14/279 (5%)
Query: 565 PNQAVREFAREIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTER 624
P + + A EI + +E +G G+FG+V A+ VA+KT+KPGS
Sbjct: 246 PQKPWEKDAWEIPRESLKLEKKLGAGQFGEVWM------ATYNKHTKVAVKTMKPGSM-- 297
Query: 625 ARRDFLAEASIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFRVL- 683
+ FLAEA++M +H ++ L VVTK PI IITEFM GSL FL++++G + L
Sbjct: 298 SVEAFLAEANVMKTLQHDKLVKLHAVVTK-EPIYIITEFMAKGSLLDFLKSDEGSKQPLP 356
Query: 684 QLVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTT 743
+L+ IA GM ++ + NYIHRDL A N+LV++ LVCKIADFGL+R IE D YT
Sbjct: 357 KLIDFSAQIAEGMAFIEQRNYIHRDLRAANILVSASLVCKIADFGLARVIE---DNEYTA 413
Query: 744 R-GGKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKG 802
R G K P++WTAPEAI F FT SDVWS GI+ E++++G PY SN +VI+++E+G
Sbjct: 414 REGAKFPIKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPEVIRALERG 473
Query: 803 YRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLD 841
YR+P P +CPE +Y +M+ CW+ RPTF I LD
Sbjct: 474 YRMPRPENCPEELYNIMMRCWKNRPEERPTFEYIQSVLD 512
>UniRef50_A7SFD8 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 229
Score = 237 bits (580), Expect = 1e-60
Identities = 112/223 (50%), Positives = 157/223 (70%), Gaps = 11/223 (4%)
Query: 610 IDVAIKTLKPGSTERARRDFLAEASIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSL 669
+ VA+K L+ S R FL EA+IM QF H NV+++ GVVT NPIMI+ E M G+L
Sbjct: 1 VQVAVKMLRDSSDSEDRVKFLQEAAIMRQFTHRNVVYMYGVVTNSNPIMIVLEHMSLGNL 60
Query: 670 DTFL---RANDGKFRVL------QLVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQL 720
+L R GK VL QL+GM+R IA GMQYL + ++HRDLAARN+L++S +
Sbjct: 61 RNYLLNLRLKYGKEVVLCLDTRSQLLGMIRDIAAGMQYLHSLGFVHRDLAARNILLDSDM 120
Query: 721 VCKIADFGLSREIESTADGAYTTRGGKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVM 780
+CKI DFG+SR++ D YT+RGG+IPV+WTAPEAI + +++SASDVWS G++ +E+
Sbjct: 121 ICKIGDFGMSRDL-MICD-YYTSRGGRIPVKWTAPEAINYGRYSSASDVWSYGVLLFEIW 178
Query: 781 SFGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEAVYQLMLDCW 823
S G++PY N N +V++++ +GYRLP P CP +Y+LM+DCW
Sbjct: 179 SLGDKPYANLDNNEVVEAVSRGYRLPPPDHCPTMIYRLMVDCW 221
>UniRef50_UPI0000E814D8 Cluster: PREDICTED: similar to Ephrin type-A
receptor 2 precursor (Tyrosine-protein kinase receptor
ECK) (Epithelial cell kinase); n=2; Gallus gallus|Rep:
PREDICTED: similar to Ephrin type-A receptor 2 precursor
(Tyrosine-protein kinase receptor ECK) (Epithelial cell
kinase) - Gallus gallus
Length = 373
Score = 236 bits (578), Expect = 2e-60
Identities = 113/212 (53%), Positives = 146/212 (68%), Gaps = 3/212 (1%)
Query: 731 REIESTADGAYTTRGGKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNW 790
RE T GGKIP+RWTAPEAI++RKFTSASDVWS GIV WEVMS+GERPYW
Sbjct: 159 RECPKTTHIFPKKHGGKIPIRWTAPEAISYRKFTSASDVWSYGIVMWEVMSYGERPYWEL 218
Query: 791 SNQDVIKSIEKGYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLIRCPDTL 850
SN +V+K+I +G+RLPAP+DCP AVYQLM+ CWQ+ER RP F+ IV LDKL+R PD+L
Sbjct: 219 SNHEVMKAINEGFRLPAPLDCPSAVYQLMMQCWQQERARRPKFADIVSILDKLVRAPDSL 278
Query: 851 RKIA--QNRSADPLAGDT-PDLIQFTSVEEWLECIKMSRYIEKFRAAGISDMDAVVDLTV 907
+ +A R + L + D + F SV EWLE IKM +Y E F AAG S ++ V+ +T
Sbjct: 279 KALADFDPRVSIRLPSTSGSDGVPFRSVPEWLESIKMHQYAEHFAAAGYSTIEKVLQMTS 338
Query: 908 HQLASLGVTLVGHQKKIMNSVQSMRAQIRGSG 939
L +GV L GH+K+I S+ ++ Q+ +G
Sbjct: 339 DDLKKIGVRLPGHKKRIAYSLLGLQEQLCPAG 370
Score = 120 bits (289), Expect = 2e-25
Identities = 60/100 (60%), Positives = 74/100 (74%), Gaps = 3/100 (3%)
Query: 554 RTYIDPHTYEDPNQAVREFAREIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVA 613
+TY+DPHTYEDPNQA+ +F EI S IT + +IG GEFG+V +G LK E+ VA
Sbjct: 62 KTYVDPHTYEDPNQAMLKFTTEISPSSITRQKVIGAGEFGEVYKGTLKQGKK---EVPVA 118
Query: 614 IKTLKPGSTERARRDFLAEASIMGQFEHPNVIFLQGVVTK 653
IKTLK G TE+ R DFL+EASIMGQF H N+I L+GVV+K
Sbjct: 119 IKTLKVGYTEKQRVDFLSEASIMGQFCHHNIIRLEGVVSK 158
>UniRef50_Q66I04 Cluster: Zgc:92124; n=1; Danio rerio|Rep: Zgc:92124
- Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 510
Score = 233 bits (569), Expect = 2e-59
Identities = 121/271 (44%), Positives = 169/271 (62%), Gaps = 13/271 (4%)
Query: 573 AREIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAE 632
A EI I + +G G+FG+V A VA+KTLKPG+ + FL E
Sbjct: 237 AWEISKDSIKMVKKLGAGQFGEVWM------AFYNNSTKVAVKTLKPGTM--SVEAFLEE 288
Query: 633 ASIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRANDG-KFRVLQLVGMLRG 691
A++M +H ++ L VVTK PI IITE+M NGSL FL++ G K ++ +L+
Sbjct: 289 ANLMKTLQHDRLVRLYAVVTKTEPIYIITEYMANGSLLDFLKSQAGSKIQLPKLIDFSAQ 348
Query: 692 IATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTR-GGKIPV 750
IA GM Y+ + NYIHRDL A NVLV+ L+CKIADFGL+R IE D YT R G K P+
Sbjct: 349 IAEGMAYIEKKNYIHRDLRAANVLVSEMLLCKIADFGLARVIE---DDQYTAREGAKFPI 405
Query: 751 RWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMD 810
+WTAPEAI + FT SD+WS G++ +E++++G+ PY SN +V+ S+++GYR+P P +
Sbjct: 406 KWTAPEAINYGSFTIKSDMWSFGVLLYEIITYGKIPYPGMSNSEVMSSVQRGYRMPRPEN 465
Query: 811 CPEAVYQLMLDCWQKERTHRPTFSSIVKTLD 841
CP +Y++M CW+ + RPTF I LD
Sbjct: 466 CPVELYEIMTTCWKNKPEDRPTFDYIQSVLD 496
>UniRef50_P07947 Cluster: Proto-oncogene tyrosine-protein kinase
Yes; n=422; root|Rep: Proto-oncogene tyrosine-protein
kinase Yes - Homo sapiens (Human)
Length = 543
Score = 233 bits (569), Expect = 2e-59
Identities = 129/283 (45%), Positives = 171/283 (60%), Gaps = 14/283 (4%)
Query: 561 TYEDPNQAVREFAREIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPG 620
T + Q + + A EI + +E +G G FG+V G + VAIKTLKPG
Sbjct: 257 TVKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMG------TWNGTTKVAIKTLKPG 310
Query: 621 STERARRDFLAEASIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRANDGKF 680
+ FL EA IM + H ++ L VV++ PI I+TEFM GSL FL+ DGK+
Sbjct: 311 TM--MPEAFLQEAQIMKKLRHDKLVPLYAVVSE-EPIYIVTEFMSKGSLLDFLKEGDGKY 367
Query: 681 RVL-QLVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADG 739
L QLV M IA GM Y+ MNYIHRDL A N+LV LVCKIADFGL+R IE D
Sbjct: 368 LKLPQLVDMAAQIADGMAYIERMNYIHRDLRAANILVGENLVCKIADFGLARLIE---DN 424
Query: 740 AYTTR-GGKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKS 798
YT R G K P++WTAPEA + +FT SDVWS GI+ E+++ G PY N++V++
Sbjct: 425 EYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILQTELVTKGRVPYPGMVNREVLEQ 484
Query: 799 IEKGYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLD 841
+E+GYR+P P CPE++++LM CW+K+ RPTF I L+
Sbjct: 485 VERGYRMPCPQGCPESLHELMNLCWKKDPDERPTFEYIQSFLE 527
>UniRef50_Q7QAK4 Cluster: ENSANGP00000020257; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000020257 - Anopheles gambiae
str. PEST
Length = 1192
Score = 232 bits (567), Expect = 4e-59
Identities = 119/262 (45%), Positives = 156/262 (59%), Gaps = 11/262 (4%)
Query: 587 IGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEASIMGQFEHPNVIF 646
IG G FGDV + KLK VA+KT + E +R FL E I+ Q++HPN++
Sbjct: 937 IGRGNFGDVYKAKLK----SSKNTLVAVKTCRMTLPEEQKRKFLQEGRILKQYDHPNIVK 992
Query: 647 LQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFRVLQLVGMLRGIATGMQYLSEMNYIH 706
L G+ + PIMI+ E + GSL FLR N Q++GM R A GM+YL N IH
Sbjct: 993 LIGICVQKQPIMIVMELVAGGSLLMFLRKNASTLGQRQMMGMCRDAAAGMRYLESKNCIH 1052
Query: 707 RDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGG--KIPVRWTAPEAIAFRKFT 764
RDLAARN L+ S+ + KI+DFG+SRE E Y GG +IP++WTAPEA+ F K+T
Sbjct: 1053 RDLAARNCLIGSENIVKISDFGMSREEEE-----YIVSGGMKQIPIKWTAPEALNFGKYT 1107
Query: 765 SASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEAVYQLMLDCWQ 824
S DVWS GI+ WE+ S G+ PY SN + I++GYR+PAP P +Y+LML CW
Sbjct: 1108 SLCDVWSYGILVWEIFSRGDTPYSGMSNSMARERIDEGYRMPAPEGAPPEMYRLMLKCWS 1167
Query: 825 KERTHRPTFSSIVKTLDKLIRC 846
E RP F I +D L+ C
Sbjct: 1168 YEPESRPHFDEICSVVDALLLC 1189
>UniRef50_P42685 Cluster: Tyrosine-protein kinase FRK; n=27;
Fungi/Metazoa group|Rep: Tyrosine-protein kinase FRK -
Homo sapiens (Human)
Length = 505
Score = 227 bits (556), Expect = 8e-58
Identities = 120/264 (45%), Positives = 163/264 (61%), Gaps = 10/264 (3%)
Query: 575 EIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEAS 634
EID + I + +G G+FG+V G L + P VA+KTLKPGS + DFL EA
Sbjct: 228 EIDRNSIQLLKRLGSGQFGEVWEG---LWNNTTP---VAVKTLKPGSMDP--NDFLREAQ 279
Query: 635 IMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRANDG-KFRVLQLVGMLRGIA 693
IM HP +I L V T +PI IITE M +GSL +L+ + G K + Q V M +A
Sbjct: 280 IMKNLRHPKLIQLYAVCTLEDPIYIITELMRHGSLQEYLQNDTGSKIHLTQQVDMAAQVA 339
Query: 694 TGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGG-KIPVRW 752
+GM YL NYIHRDLAARNVLV + K+ADFGL+R + + Y +R K+PV+W
Sbjct: 340 SGMAYLESRNYIHRDLAARNVLVGEHNIYKVADFGLARVFKVDNEDIYESRHEIKLPVKW 399
Query: 753 TAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCP 812
TAPEAI KF+ SDVWS GI+ +E++++G+ PY + VI+ + + YRLP P +CP
Sbjct: 400 TAPEAIRSNKFSIKSDVWSFGILLYEIITYGKMPYSGMTGAQVIQMLAQNYRLPQPSNCP 459
Query: 813 EAVYQLMLDCWQKERTHRPTFSSI 836
+ Y +ML+CW E RPTF ++
Sbjct: 460 QQFYNIMLECWNAEPKERPTFETL 483
>UniRef50_P18106 Cluster: Tyrosine-protein kinase Fps85D; n=12;
Eumetazoa|Rep: Tyrosine-protein kinase Fps85D -
Drosophila melanogaster (Fruit fly)
Length = 1325
Score = 227 bits (556), Expect = 8e-58
Identities = 117/260 (45%), Positives = 156/260 (60%), Gaps = 12/260 (4%)
Query: 587 IGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEASIMGQFEHPNVIF 646
IG G FGDV + KLK ++DVA+KT + + +R FL E I+ Q++HPN++
Sbjct: 1069 IGRGNFGDVYKAKLK-----STKLDVAVKTCRMTLPDEQKRKFLQEGRILKQYDHPNIVK 1123
Query: 647 LQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFRVLQLVGMLRGIATGMQYLSEMNYIH 706
L G+ + PIMI+ E + GSL T+LR N Q +GM R A GM+YL N IH
Sbjct: 1124 LIGICVQKQPIMIVMELVLGGSLLTYLRKNSNGLTTRQQMGMCRDAAAGMRYLESKNCIH 1183
Query: 707 RDLAARNVLVNSQLVCKIADFGLSREIES--TADGAYTTRGGKIPVRWTAPEAIAFRKFT 764
RDLAARN LV+ + KI+DFG+SRE E +DG +IPV+WTAPEA+ F K+T
Sbjct: 1184 RDLAARNCLVDLEHSVKISDFGMSREEEEYIVSDGM-----KQIPVKWTAPEALNFGKYT 1238
Query: 765 SASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEAVYQLMLDCWQ 824
S DVWS GI+ WE+ S G+ PY +N + I+ GYR+P P PE +Y+LML CW
Sbjct: 1239 SLCDVWSYGILMWEIFSKGDTPYSGMTNSRARERIDTGYRMPTPKSTPEEMYRLMLQCWA 1298
Query: 825 KERTHRPTFSSIVKTLDKLI 844
+ RP F I +D LI
Sbjct: 1299 ADAESRPHFDEIYNVVDALI 1318
>UniRef50_Q2VXS7 Cluster: Proto-oncogene c-fes variant 4; n=77;
Eutheria|Rep: Proto-oncogene c-fes variant 4 - Homo
sapiens (Human)
Length = 752
Score = 224 bits (548), Expect = 8e-57
Identities = 116/259 (44%), Positives = 157/259 (60%), Gaps = 10/259 (3%)
Query: 587 IGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEASIMGQFEHPNVIF 646
IG G FG+V G+L+ + VA+K+ + + FL EA I+ Q+ HPN++
Sbjct: 497 IGRGNFGEVFSGRLRADNTL-----VAVKSCRETLPPDLKAKFLQEARILKQYSHPNIVR 551
Query: 647 LQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFRVLQLVGMLRGIATGMQYLSEMNYIH 706
L GV T+ PI I+ E ++ G TFLR + RV L+ M+ A GM+YL IH
Sbjct: 552 LIGVCTQKQPIYIVMELVQGGDFLTFLRTEGARLRVKTLLQMVGDAAAGMEYLESKCCIH 611
Query: 707 RDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGG--KIPVRWTAPEAIAFRKFT 764
RDLAARN LV + V KI+DFG+SRE ADG Y GG ++PV+WTAPEA+ + +++
Sbjct: 612 RDLAARNCLVTEKNVLKISDFGMSRE---EADGVYAASGGSRQVPVKWTAPEALNYGRYS 668
Query: 765 SASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEAVYQLMLDCWQ 824
S SDVWS GI+ WE S G PY N SNQ + +EKG RLP P CP+AV++LM CW
Sbjct: 669 SESDVWSFGILLWETFSLGASPYPNLSNQQTREFVEKGGRLPCPELCPDAVFRLMEQCWA 728
Query: 825 KERTHRPTFSSIVKTLDKL 843
E RP+FS+I + L +
Sbjct: 729 YEPGQRPSFSTIYQELQSI 747
>UniRef50_P00522 Cluster: Tyrosine-protein kinase Abl; n=5;
Eumetazoa|Rep: Tyrosine-protein kinase Abl - Drosophila
melanogaster (Fruit fly)
Length = 1620
Score = 221 bits (541), Expect = 5e-56
Identities = 119/273 (43%), Positives = 164/273 (60%), Gaps = 12/273 (4%)
Query: 575 EIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEAS 634
EI + I ++ +GGG++G+V K + VA+KTLK + A +DFL EA+
Sbjct: 365 EICRTDIMMKHKLGGGQYGEVYEAVWKRYGNT-----VAVKTLKEDTM--ALKDFLEEAA 417
Query: 635 IMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLR-ANDGKFRVLQLVGMLRGIA 693
IM + +HPN++ L GV T+ P IITEFM +G+L FLR A + L+ M IA
Sbjct: 418 IMKEMKHPNLVQLIGVCTREPPFYIITEFMSHGNLLDFLRSAGRETLDAVALLYMATQIA 477
Query: 694 TGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGG-KIPVRW 752
+GM YL NYIHRDLAARN LV + K+ADFGL+R + D YT G K P++W
Sbjct: 478 SGMSYLESRNYIHRDLAARNCLVGDNKLVKVADFGLARLMR---DDTYTAHAGAKFPIKW 534
Query: 753 TAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCP 812
TAPE +A+ KF++ SDVW+ G++ WE+ ++G PY DV ++KGYR+ P CP
Sbjct: 535 TAPEGLAYNKFSTKSDVWAFGVLLWEIATYGMSPYPAIDLTDVYHKLDKGYRMERPPGCP 594
Query: 813 EAVYQLMLDCWQKERTHRPTFSSIVKTLDKLIR 845
VY LM CWQ + T RPTF SI L+ + +
Sbjct: 595 PEVYDLMRQCWQWDATDRPTFKSIHHALEHMFQ 627
>UniRef50_UPI00015B4B0F Cluster: PREDICTED: similar to
proto-oncogene tyrosine-protein kinase abl1; n=1;
Nasonia vitripennis|Rep: PREDICTED: similar to
proto-oncogene tyrosine-protein kinase abl1 - Nasonia
vitripennis
Length = 1522
Score = 220 bits (537), Expect = 2e-55
Identities = 118/274 (43%), Positives = 166/274 (60%), Gaps = 14/274 (5%)
Query: 575 EIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEAS 634
EI+ + I + +GGG++GDV K + VA+KTLK + A +DFL EA+
Sbjct: 284 EINRTDIVMRHKLGGGQYGDVYEAVWKRY-----NMTVAVKTLKEDTM--ALKDFLEEAA 336
Query: 635 IMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFRV--LQLVGMLRGI 692
IM + +H N++ L GV T+ P IITEFM G+L +LR N+ K ++ + L+ M I
Sbjct: 337 IMKEMKHRNLVQLIGVCTREPPFYIITEFMSKGNLLDYLR-NESKHQINAVVLMHMATQI 395
Query: 693 ATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGG-KIPVR 751
A+GM YL N+IHRDLAARN LV + K+ADFGL+R + D YT G K P++
Sbjct: 396 ASGMSYLESRNFIHRDLAARNCLVGESHLVKVADFGLARLMR---DDTYTAHAGAKFPIK 452
Query: 752 WTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDC 811
WTAPE +A+ KF++ SDVW+ GI+ WE+ ++G PY DV +EKGYR+ P C
Sbjct: 453 WTAPEGLAYNKFSTKSDVWAFGILLWEIATYGMSPYPGVDLTDVYHMLEKGYRMECPPGC 512
Query: 812 PEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLIR 845
P VY+LM CWQ + RPTF I +L+ + +
Sbjct: 513 PPKVYELMRQCWQWSASDRPTFKEIHHSLENMFQ 546
>UniRef50_UPI0000519AF4 Cluster: PREDICTED: similar to Abl tyrosine
kinase CG4032-PA; n=1; Apis mellifera|Rep: PREDICTED:
similar to Abl tyrosine kinase CG4032-PA - Apis
mellifera
Length = 1439
Score = 220 bits (537), Expect = 2e-55
Identities = 118/274 (43%), Positives = 165/274 (60%), Gaps = 14/274 (5%)
Query: 575 EIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEAS 634
EI+ + I + +GGG++GDV K + VA+KTLK + A +DFL EA+
Sbjct: 283 EINRTDIVMRHKLGGGQYGDVYEAVWKRY-----NMTVAVKTLKEDTM--ALKDFLEEAA 335
Query: 635 IMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFRV--LQLVGMLRGI 692
IM + +H N++ L GV T+ P IITEFM G+L +LR N+ K ++ + L+ M I
Sbjct: 336 IMKEMKHRNLVQLLGVCTREPPFYIITEFMSKGNLLDYLR-NESKHQINAVVLMHMATQI 394
Query: 693 ATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGG-KIPVR 751
A+GM YL N+IHRDLAARN LV + K+ADFGL+R + D YT G K P++
Sbjct: 395 ASGMSYLESRNFIHRDLAARNCLVGENHLVKVADFGLARLMR---DDTYTAHAGAKFPIK 451
Query: 752 WTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDC 811
WTAPE +A+ KF++ SDVW+ GI+ WE+ ++G PY DV +EKGYR+ P C
Sbjct: 452 WTAPEGLAYNKFSTKSDVWAFGILLWEIATYGMSPYPGVDLTDVYHMLEKGYRMECPPGC 511
Query: 812 PEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLIR 845
P VY+LM CWQ RPTF I +L+ + +
Sbjct: 512 PPKVYELMRQCWQWSAADRPTFKEIHHSLENMFQ 545
>UniRef50_Q05397 Cluster: Focal adhesion kinase 1; n=111;
Euteleostomi|Rep: Focal adhesion kinase 1 - Homo sapiens
(Human)
Length = 1052
Score = 220 bits (537), Expect = 2e-55
Identities = 111/270 (41%), Positives = 158/270 (58%), Gaps = 5/270 (1%)
Query: 575 EIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEAS 634
EI I + IG G+FGDV +G P + P + VAIKT K +++ R FL EA
Sbjct: 416 EIQRERIELGRCIGEGQFGDVHQGIYMSPEN--PALAVAIKTCKNCTSDSVREKFLQEAL 473
Query: 635 IMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFRVLQLVGMLRGIAT 694
M QF+HP+++ L GV+T+ NP+ II E G L +FL+ + L+ ++T
Sbjct: 474 TMRQFDHPHIVKLIGVITE-NPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLST 532
Query: 695 GMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGGKIPVRWTA 754
+ YL ++HRD+AARNVLV+S K+ DFGLSR +E + Y GK+P++W A
Sbjct: 533 ALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDST--YYKASKGKLPIKWMA 590
Query: 755 PEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEA 814
PE+I FR+FTSASDVW G+ WE++ G +P+ N DVI IE G RLP P +CP
Sbjct: 591 PESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPT 650
Query: 815 VYQLMLDCWQKERTHRPTFSSIVKTLDKLI 844
+Y LM CW + + RP F+ + L ++
Sbjct: 651 LYSLMTKCWAYDPSRRPRFTELKAQLSTIL 680
>UniRef50_Q573B4 Cluster: Proto-oncogene tyrosine-protein kinase
LCK; n=11; Coelomata|Rep: Proto-oncogene
tyrosine-protein kinase LCK - Homo sapiens (Human)
Length = 516
Score = 218 bits (533), Expect = 5e-55
Identities = 114/232 (49%), Positives = 152/232 (65%), Gaps = 8/232 (3%)
Query: 612 VAIKTLKPGSTERARRDFLAEASIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDT 671
VA+K+LK GS FLAEA++M Q +H ++ L VVT+ PI IITE+MENGSL
Sbjct: 277 VAVKSLKQGSMSPDA--FLAEANLMKQLQHQRLVRLYAVVTQ-EPIYIITEYMENGSLVD 333
Query: 672 FLRANDG-KFRVLQLVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLS 730
FL+ G K + +L+ M IA GM ++ E NYIHRDL A N+LV+ L CKIADFGL+
Sbjct: 334 FLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLA 393
Query: 731 REIESTADGAYTTR-GGKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWN 789
R IE D YT R G K P++WTAPEAI + FT SDVWS GI+ E+++ G PY
Sbjct: 394 RLIE---DNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPG 450
Query: 790 WSNQDVIKSIEKGYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLD 841
+N +VI+++E+GYR+ P +CPE +YQLM CW++ RPTF + L+
Sbjct: 451 MTNPEVIQNLERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLE 502
>UniRef50_Q24488 Cluster: Tyrosine-protein kinase transmembrane
receptor Ror precursor; n=1; Drosophila
melanogaster|Rep: Tyrosine-protein kinase transmembrane
receptor Ror precursor - Drosophila melanogaster (Fruit
fly)
Length = 685
Score = 218 bits (533), Expect = 5e-55
Identities = 113/258 (43%), Positives = 158/258 (61%), Gaps = 7/258 (2%)
Query: 587 IGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEASIMGQFEHPNVIF 646
+G G FG V +G+L P I VAIK LK ++ + ++DF E ++ +H N++
Sbjct: 416 LGEGAFGKVYKGQLLQPNKT--TITVAIKALKENASVKTQQDFKREIELISDLKHQNIVC 473
Query: 647 LQGVVTKCNPIMIITEFMENGSLDTFLRAN---DGK-FRVLQLVGMLRGIATGMQYLSEM 702
+ GVV P ++ E+M NG L FL +N +GK L+ + + I+ GMQYLS
Sbjct: 474 ILGVVLNKEPYCMLFEYMANGDLHEFLISNSPTEGKSLSQLEFLQIALQISEGMQYLSAH 533
Query: 703 NYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGGKIPVRWTAPEAIAFRK 762
+Y+HRDLAARN LVN LV KI+DFGLSR+I S+ D +PVRW E+I + K
Sbjct: 534 HYVHRDLAARNCLVNEGLVVKISDFGLSRDIYSS-DYYRVQSKSLLPVRWMPSESILYGK 592
Query: 763 FTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEAVYQLMLDC 822
FT+ SDVWS G+V WE+ S+G +PY+ +SNQ+VI I L AP +CP AVY LM++C
Sbjct: 593 FTTESDVWSFGVVLWEIYSYGMQPYYGFSNQEVINLIRSRQLLSAPENCPTAVYSLMIEC 652
Query: 823 WQKERTHRPTFSSIVKTL 840
W ++ RPTF+ I L
Sbjct: 653 WHEQSVKRPTFTDISNRL 670
>UniRef50_Q8T6F8 Cluster: SRC-1; n=3; Caenorhabditis|Rep: SRC-1 -
Caenorhabditis elegans
Length = 533
Score = 218 bits (532), Expect = 7e-55
Identities = 117/273 (42%), Positives = 164/273 (60%), Gaps = 16/273 (5%)
Query: 575 EIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEAS 634
EI + + ++ +G G FG+V GK + ++VAIKT+KPG+ + FL EA
Sbjct: 256 EIPRNQLHLKRKLGDGNFGEVWYGKWR------GIVEVAIKTMKPGTM--SPEAFLQEAQ 307
Query: 635 IMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFRVLQLVGMLRGIAT 694
IM Q +HPN++ L V T+ P IITE+M NGSL +LR + + LV M IA
Sbjct: 308 IMKQCDHPNLVKLYAVCTREEPFYIITEYMINGSLLQYLRTDGSTLGIQALVDMAAQIAN 367
Query: 695 GMQYLSEMNYIHRDLAARNVLVNSQL----VCKIADFGLSREIESTADGAYTTR-GGKIP 749
GM YL E +HRDLAARNVLV ++ V K+ADFGL+R++ + Y R G K P
Sbjct: 368 GMMYLEERKLVHRDLAARNVLVGDKISGVPVVKVADFGLARKL--MEEDIYEARTGAKFP 425
Query: 750 VRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPM 809
++WTAPEA FT SDVWS GI+ +E+M+ G+ PY N++V++ +E GYR+P P
Sbjct: 426 IKWTAPEAATCGNFTVKSDVWSYGILLYEIMTKGQVPYPGMHNREVVEQVELGYRMPMPR 485
Query: 810 DCPEAVY-QLMLDCWQKERTHRPTFSSIVKTLD 841
CPE +Y +++L CW K RPTF ++ D
Sbjct: 486 GCPEQIYEEVLLKCWDKTPDRRPTFDTLYHFFD 518
>UniRef50_P16591 Cluster: Proto-oncogene tyrosine-protein kinase
FER; n=109; root|Rep: Proto-oncogene tyrosine-protein
kinase FER - Homo sapiens (Human)
Length = 822
Score = 217 bits (531), Expect = 9e-55
Identities = 110/261 (42%), Positives = 156/261 (59%), Gaps = 10/261 (3%)
Query: 581 ITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEASIMGQFE 640
+ + ++G G FG+V +G LK S VA+KT K + + FL EA I+ Q++
Sbjct: 563 VILGELLGKGNFGEVYKGTLKDKTS------VAVKTCKEDLPQELKIKFLQEAKILKQYD 616
Query: 641 HPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFRVLQLVGMLRGIATGMQYLS 700
HPN++ L GV T+ P+ II E + G TFLR + ++ QLV A GM YL
Sbjct: 617 HPNIVKLIGVCTQRQPVYIIMELVSGGDFLTFLRRKKDELKLKQLVKFSLDAAAGMLYLE 676
Query: 701 EMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGGK-IPVRWTAPEAIA 759
N IHRDLAARN LV V KI+DFG+SR+ + G Y++ G K IP++WTAPEA+
Sbjct: 677 SKNCIHRDLAARNCLVGENNVLKISDFGMSRQEDG---GVYSSSGLKQIPIKWTAPEALN 733
Query: 760 FRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEAVYQLM 819
+ +++S SDVWS GI+ WE S G PY +NQ + +E+GYR+ AP CPE + ++M
Sbjct: 734 YGRYSSESDVWSFGILLWETFSLGVCPYPGMTNQQAREQVERGYRMSAPQHCPEDISKIM 793
Query: 820 LDCWQKERTHRPTFSSIVKTL 840
+ CW + +RP FS + K L
Sbjct: 794 MKCWDYKPENRPKFSELQKEL 814
>UniRef50_Q70DV1 Cluster: Src tyrosine kinase; n=1; Schistosoma
mansoni|Rep: Src tyrosine kinase - Schistosoma mansoni
(Blood fluke)
Length = 647
Score = 216 bits (527), Expect = 3e-54
Identities = 116/275 (42%), Positives = 163/275 (59%), Gaps = 13/275 (4%)
Query: 575 EIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEAS 634
EI S I ++ IG G+FG+V + A VA+KTLKP S + A DFL EA
Sbjct: 340 EIPKSSIILKEKIGQGQFGEVFK------AVWNKTTIVAVKTLKPSSCDAA--DFLREAQ 391
Query: 635 IMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFRVLQ-LVGMLRGIA 693
M + HPN+I L V T+ P I+TE+M GSL +L++ +G +Q L+ M IA
Sbjct: 392 TMKRLHHPNLIQLYAVCTQTEPFYIVTEYMSKGSLLNYLQSPEGNALNMQCLIMMAAKIA 451
Query: 694 TGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGGKIPVRWT 753
GM YL +IHRDLAARNVLV Q KIADFGL+R I + A+ G + P++WT
Sbjct: 452 PGMAYLESRRHIHRDLAARNVLVGEQHAVKIADFGLARMIHNREYVAHA--GARFPIKWT 509
Query: 754 APEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCPE 813
+PEA + +FT SDVWS GI+ E++++G PY N +V++ ++ GYR+ P CP
Sbjct: 510 SPEAANYSRFTIKSDVWSFGILLTEIVTYGRSPYPGMHNAEVLRQVDAGYRMSKPPGCPP 569
Query: 814 AVYQLMLDCWQKERTHRPTFSSIVKTLDKLIRCPD 848
+Y LML+CW + RP+F++I L++ C D
Sbjct: 570 ELYDLMLECWAADENKRPSFATIHFRLEQF--CED 602
>UniRef50_Q9Y1Z0 Cluster: Protein tyrosine kinase; n=1; Ephydatia
fluviatilis|Rep: Protein tyrosine kinase - Ephydatia
fluviatilis
Length = 485
Score = 215 bits (526), Expect = 4e-54
Identities = 107/262 (40%), Positives = 160/262 (61%), Gaps = 14/262 (5%)
Query: 584 EAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPG-STERARRDFLAEASIMGQFEHP 642
+++IG GEFG+V G + G + VA+K++K E+A+ FLAEAS+M HP
Sbjct: 229 KSLIGKGEFGEVWLGDYE-----GKK--VAMKSMKDHLKDEKAKTQFLAEASVMTTLRHP 281
Query: 643 NVIFLQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFRVLQ-LVGMLRGIATGMQYLSE 701
N++ L G+ NPI +ITEFM GSL +LR+ Q + R + GM YL
Sbjct: 282 NLVCLIGISLDDNPIYLITEFMAKGSLIDYLRSRGRAVITKQNQIDFARDVVKGMVYLES 341
Query: 702 MNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGGKIPVRWTAPEAIAFR 761
N++HRDLAARNVL+ V K++DFGL++ + G K+PV+WTAPEA+
Sbjct: 342 QNFVHRDLAARNVLIAEDNVAKVSDFGLAKSSSNVKQ-----EGAKLPVKWTAPEALREN 396
Query: 762 KFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEAVYQLMLD 821
KF++ +DVWS G++ WE+ S+G PY +DV +E GYR+ +P CP+ +Y++M+D
Sbjct: 397 KFSNKTDVWSFGVLLWEIYSYGRVPYPRVPVEDVANHVENGYRMESPDGCPDQIYKIMMD 456
Query: 822 CWQKERTHRPTFSSIVKTLDKL 843
CW+K+ + RP F+ I K L+ +
Sbjct: 457 CWEKDPSQRPNFTRIEKALESV 478
>UniRef50_Q8WPV5 Cluster: Tyrosine kinase; n=2; Eumetazoa|Rep:
Tyrosine kinase - Schistosoma mansoni (Blood fluke)
Length = 1264
Score = 215 bits (526), Expect = 4e-54
Identities = 104/271 (38%), Positives = 161/271 (59%), Gaps = 5/271 (1%)
Query: 576 IDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERA-RRDFLAEAS 634
+++ +T++ +GGG FG V +G + P+ G E+ VA+KTLKP + R+ LAEA
Sbjct: 883 LNSQTVTLKERLGGGNFGHVVKGLYRTPS--GQEVPVAVKTLKPNQIANSGEREILAEAR 940
Query: 635 IMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFRVLQLVGMLRGIAT 694
M Q +H +++ L GV K M++ E G ++ +L+ V L ++ +A
Sbjct: 941 TMAQLKHRHIVRLIGVC-KEEQFMLVLELAPLGPINKYLKKRPD-VSVHTLTELMHQVAL 998
Query: 695 GMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGGKIPVRWTA 754
GM YL ++HRDLAARNVL+ ++ KI+DFG+S+ + +D GK P++W A
Sbjct: 999 GMAYLESCKFVHRDLAARNVLLVTRHFAKISDFGMSKALNFGSDYYRAATAGKWPLKWYA 1058
Query: 755 PEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEA 814
PE I + +F S SDVWS GI WEV S+GERPY + ++ +++G RL P CPE+
Sbjct: 1059 PECIYYFRFDSKSDVWSYGITLWEVYSYGERPYRDMKGAQILAMLDQGLRLSRPSRCPES 1118
Query: 815 VYQLMLDCWQKERTHRPTFSSIVKTLDKLIR 845
+Y +M CW E HRPTF+ +V T+ +++R
Sbjct: 1119 IYSIMQQCWNFEGVHRPTFAELVLTISRILR 1149
>UniRef50_Q9NH62 Cluster: Tyrosine kinase 5; n=2; Schistosoma
mansoni|Rep: Tyrosine kinase 5 - Schistosoma mansoni
(Blood fluke)
Length = 647
Score = 215 bits (525), Expect = 5e-54
Identities = 115/283 (40%), Positives = 166/283 (58%), Gaps = 10/283 (3%)
Query: 575 EIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEAS 634
EI S I + +G G+FG+V +G + +VA+KTLK G+ + DFL EA
Sbjct: 298 EISKSSIVLIEKLGAGQFGEVWKG------TWNGTTEVAVKTLKQGTM--TKEDFLKEAR 349
Query: 635 IMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFRVL-QLVGMLRGIA 693
IM +HP ++ L V T+ +PI I+TE M NGSL +LR GK ++ QLV M+ IA
Sbjct: 350 IMRAAQHPKLVRLYAVCTE-DPIYIVTELMCNGSLLQYLRDGPGKNLLINQLVDMMAQIA 408
Query: 694 TGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGGKIPVRWT 753
GM YL + +YIHRDLAARN+LV K+ADFGL+R +E + K P++WT
Sbjct: 409 NGMAYLEKEHYIHRDLAARNILVGENNCVKVADFGLARMVEDHYCTYMAQKSTKFPIKWT 468
Query: 754 APEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCPE 813
APEA +FT SDVWS GIV +E+++ G+ PY + +N + + + GYR+P P++CP+
Sbjct: 469 APEAALMGRFTIKSDVWSFGIVIYELITLGQVPYPSMNNTETLHQVSTGYRMPRPVNCPQ 528
Query: 814 AVYQLMLDCWQKERTHRPTFSSIVKTLDKLIRCPDTLRKIAQN 856
+Y ++L W RPTFSS+ + + D K A +
Sbjct: 529 PIYDMLLRIWDSCPEKRPTFSSLFEFFEDYFVTSDANYKHANS 571
>UniRef50_Q6R1Y3 Cluster: Src family kinase; n=6; Fungi/Metazoa
group|Rep: Src family kinase - Asterina miniata (Bat
star) (Patiria miniata)
Length = 563
Score = 215 bits (525), Expect = 5e-54
Identities = 112/268 (41%), Positives = 156/268 (58%), Gaps = 12/268 (4%)
Query: 575 EIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEAS 634
EI I +E +G G+FG+V G + + VA+KTLK G+ + FL EA+
Sbjct: 296 EIPRRSIKLERKLGNGQFGEVWEG------TWNGTVRVAVKTLKEGAMDPTA--FLQEAN 347
Query: 635 IMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRANDGK-FRVLQLVGMLRGIA 693
IM + HP ++ L V ++ PI I+TE M NG L +L +GK R +L+ + +A
Sbjct: 348 IMKKLRHPKLVALLAVCSEGEPIYIVTELMTNGCLLDYLHEGEGKQLREPELIDITAQVA 407
Query: 694 TGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGGKIPVRWT 753
GM YL ++HRDLAARN+LV CK+ADFGLSR IE D G K+P++WT
Sbjct: 408 DGMAYLESQRFVHRDLAARNILVGDLRNCKVADFGLSRIIE---DEYIAKEGAKMPIKWT 464
Query: 754 APEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCPE 813
APEAI F KFT SDVWS GI+ +EV++ G PY N++V+ + +GYR+P P +CP+
Sbjct: 465 APEAINFGKFTIKSDVWSFGILIYEVITKGRVPYPGMVNREVLDQVSRGYRMPKPPECPD 524
Query: 814 AVYQLMLDCWQKERTHRPTFSSIVKTLD 841
+Y + CW RPTF + LD
Sbjct: 525 QLYDITKQCWDAVPEKRPTFEFLHSFLD 552
>UniRef50_P42680 Cluster: Tyrosine-protein kinase Tec; n=86;
Coelomata|Rep: Tyrosine-protein kinase Tec - Homo
sapiens (Human)
Length = 631
Score = 215 bits (525), Expect = 5e-54
Identities = 109/276 (39%), Positives = 164/276 (59%), Gaps = 12/276 (4%)
Query: 575 EIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEAS 634
EI+ S +T +G G FG V GK + + VAIK ++ G+ DF+ EA
Sbjct: 364 EINPSELTFMRELGSGLFGVVRLGKWRA------QYKVAIKAIREGAM--CEEDFIEEAK 415
Query: 635 IMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFRVLQLVGMLRGIAT 694
+M + HP ++ L GV T+ PI I+TEFME G L FLR G F L+ M + +
Sbjct: 416 VMMKLTHPKLVQLYGVCTQQKPIYIVTEFMERGCLLNFLRQRQGHFSRDVLLSMCQDVCE 475
Query: 695 GMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGG-KIPVRWT 753
GM+YL ++IHRDLAARN LV+ V K++DFG++R + D YT+ G K PV+W
Sbjct: 476 GMEYLERNSFIHRDLAARNCLVSEAGVVKVSDFGMARYV---LDDQYTSSSGAKFPVKWC 532
Query: 754 APEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCPE 813
PE + +F+S SDVWS G++ WEV + G P+ ++N +V+ + +G+RL P
Sbjct: 533 PPEVFNYSRFSSKSDVWSFGVLMWEVFTEGRMPFEKYTNYEVVTMVTRGHRLYQPKLASN 592
Query: 814 AVYQLMLDCWQKERTHRPTFSSIVKTLDKLIRCPDT 849
VY++ML CWQ++ RP+F +++T+D+L+ C +T
Sbjct: 593 YVYEVMLRCWQEKPEGRPSFEDLLRTIDELVECEET 628
>UniRef50_Q7Q5T3 Cluster: Tyrosine-protein kinase receptor; n=3;
Endopterygota|Rep: Tyrosine-protein kinase receptor -
Anopheles gambiae str. PEST
Length = 646
Score = 215 bits (524), Expect = 6e-54
Identities = 108/254 (42%), Positives = 153/254 (60%), Gaps = 7/254 (2%)
Query: 587 IGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEASIMGQFEHPNVIF 646
+G G FG V +G+L G I VA+K LK ++ + + DF E ++ +H N++
Sbjct: 380 LGEGAFGKVYKGELT--QKNGERIFVAVKALKENASAKTQADFKREIELISDLKHDNIVC 437
Query: 647 LQGVVTKCNPIMIITEFMENGSLDTFLRAN---DGK-FRVLQLVGMLRGIATGMQYLSEM 702
+ GVV K P+ ++ E+M G L FL AN +GK LQ + + + I GM+YL+
Sbjct: 438 ILGVVLKEEPLCMLFEYMAQGDLHEFLIANSPNEGKSLSQLQFLLIAQQICDGMEYLASH 497
Query: 703 NYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGGKIPVRWTAPEAIAFRK 762
+Y+HRDLAARN LV L KI+DFGLSR+I S+ D +PVRW E+I + K
Sbjct: 498 HYVHRDLAARNCLVGDNLTVKISDFGLSRDIYSS-DYYRVQSKSLLPVRWMPSESILYGK 556
Query: 763 FTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEAVYQLMLDC 822
FT+ SDVWS G+V WE+ S+G +PY+ +SNQ+VI + LP P CP AVY LM++C
Sbjct: 557 FTTESDVWSFGVVLWEIYSYGLQPYYGYSNQEVINMVRARQLLPCPESCPSAVYSLMVEC 616
Query: 823 WQKERTHRPTFSSI 836
W ++ RPTF I
Sbjct: 617 WHEQAVRRPTFPEI 630
>UniRef50_Q17C76 Cluster: Focal adhesion kinase; n=2; Culicidae|Rep:
Focal adhesion kinase - Aedes aegypti (Yellowfever
mosquito)
Length = 1092
Score = 214 bits (522), Expect = 1e-53
Identities = 130/352 (36%), Positives = 185/352 (52%), Gaps = 30/352 (8%)
Query: 514 KQPSDCNALNYRNGEVYTGPDRPAKTSSNATTPLFAGTGSRTYIDPH-TYEDPNQAVREF 572
KQ S ++ + N V+ D A TSSN L D Y P A R +
Sbjct: 372 KQDSTRSSSDKLNNSVHN--DLEASTSSNNKPTLNEDYAELGMCDEEGDYSTP--AARNY 427
Query: 573 AREIDASCITIEAIIGGGEFGDVCRGKLKLPASC--------------------GPEIDV 612
E+D + IT+ IIG G+FGDV G +LP+ I V
Sbjct: 428 --ELDRNHITLNEIIGVGQFGDVHIGSCRLPSKSTLFDELSLSGENNNSEVQQKSGHIQV 485
Query: 613 AIKTLKPGSTERARRDFLAEASIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTF 672
A+KT K + FL EA IM +FEHP++I L G+ + +PI I+ E G L +
Sbjct: 486 AVKTCKADADLATSEKFLEEAYIMQKFEHPHIIKLIGICSG-SPIWIVMELARLGELRAY 544
Query: 673 LRANDGKFRVLQLVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSRE 732
L+ N K ++ L+ ++T + YL ++HRD+AARNVLV+S K+ADFGLSR
Sbjct: 545 LKKNGSKLKLGTLLLYSYQLSTALSYLESKKFVHRDIAARNVLVSSPTCIKLADFGLSRW 604
Query: 733 IESTADGAYTTRGGKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSN 792
+E + YT+ G +P++W APE+I FR+FT+ASDVW G+ WE++ G +P+ N
Sbjct: 605 VEDQS--YYTSTKGMLPIKWMAPESINFRRFTTASDVWMFGVCTWEILMLGVKPFQGIKN 662
Query: 793 QDVIKSIEKGYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLI 844
DVI +E G RLP P +CP +Y LM CW E RP F +I + L +++
Sbjct: 663 CDVIGKLENGERLPLPPNCPPRLYSLMSQCWSYEPHKRPNFKNIKEVLYEIL 714
>UniRef50_P00519 Cluster: Proto-oncogene tyrosine-protein kinase
ABL1; n=35; root|Rep: Proto-oncogene tyrosine-protein
kinase ABL1 - Homo sapiens (Human)
Length = 1130
Score = 213 bits (521), Expect = 1e-53
Identities = 113/298 (37%), Positives = 175/298 (58%), Gaps = 10/298 (3%)
Query: 575 EIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEAS 634
E++ + IT++ +GGG++G+V G K + + VA+KTLK + E +FL EA+
Sbjct: 236 EMERTDITMKHKLGGGQYGEVYEGVWKKYS-----LTVAVKTLKEDTMEV--EEFLKEAA 288
Query: 635 IMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLR-ANDGKFRVLQLVGMLRGIA 693
+M + +HPN++ L GV T+ P IITEFM G+L +LR N + + L+ M I+
Sbjct: 289 VMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQIS 348
Query: 694 TGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGGKIPVRWT 753
+ M+YL + N+IHRDLAARN LV + K+ADFGLSR + T D G K P++WT
Sbjct: 349 SAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLM--TGDTYTAHAGAKFPIKWT 406
Query: 754 APEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCPE 813
APE++A+ KF+ SDVW+ G++ WE+ ++G PY V + +EK YR+ P CPE
Sbjct: 407 APESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPE 466
Query: 814 AVYQLMLDCWQKERTHRPTFSSIVKTLDKLIRCPDTLRKIAQNRSADPLAGDTPDLIQ 871
VY+LM CWQ + RP+F+ I + + + + ++ + + G L+Q
Sbjct: 467 KVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSISDEVEKELGKQGVRGAVSTLLQ 524
>UniRef50_UPI0000D577C3 Cluster: PREDICTED: similar to CG8874-PB,
isoform B; n=3; Endopterygota|Rep: PREDICTED: similar to
CG8874-PB, isoform B - Tribolium castaneum
Length = 801
Score = 213 bits (520), Expect = 2e-53
Identities = 115/259 (44%), Positives = 152/259 (58%), Gaps = 13/259 (5%)
Query: 587 IGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEASIMGQFEHPNVIF 646
IG G FGDV R +LK VA+KT + E ++ FL E I+ Q++HPN++
Sbjct: 545 IGRGNFGDVYRAQLKNSNDV-----VAVKTCRVTLPEDHKKKFLQEGRILKQYDHPNIVK 599
Query: 647 LQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFRVLQLVGMLRGIATGMQYLSEMNYIH 706
L G+ + PIMI+ E + GSL TFLR QL+ M A GM+YL N IH
Sbjct: 600 LIGICVQKQPIMIVMELVPGGSLLTFLRKKTA-LTDAQLMKMCLDAAAGMRYLESKNCIH 658
Query: 707 RDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGG--KIPVRWTAPEAIAFRKFT 764
RDLAARN LV V KI+DFG+SRE E Y G +IP++WTAPEA+ F K+T
Sbjct: 659 RDLAARNCLVGYNNVVKISDFGMSREEEE-----YIVSDGMKQIPIKWTAPEALNFGKYT 713
Query: 765 SASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEAVYQLMLDCWQ 824
S DVWS GI+CWE+ S G PY SN + I+ GYR+PAP + P+ +Y+LML CW+
Sbjct: 714 SLCDVWSYGILCWEIFSRGGTPYSGLSNSKAREKIDAGYRMPAPDNTPDEMYRLMLRCWE 773
Query: 825 KERTHRPTFSSIVKTLDKL 843
+ +RP F I ++ L
Sbjct: 774 YKPENRPNFEQIYTVVETL 792
>UniRef50_P00521 Cluster: Tyrosine-protein kinase transforming
protein Abl; n=15; root|Rep: Tyrosine-protein kinase
transforming protein Abl - Abelson murine leukemia virus
Length = 746
Score = 212 bits (518), Expect = 3e-53
Identities = 110/272 (40%), Positives = 167/272 (61%), Gaps = 10/272 (3%)
Query: 575 EIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEAS 634
E++ + IT++ +GGG++G+V G K + + VA+KTLK + E +FL EA+
Sbjct: 122 EMERTDITMKHKLGGGQYGEVYEGVWKKYS-----LTVAVKTLKEDTMEV--EEFLKEAA 174
Query: 635 IMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLR-ANDGKFRVLQLVGMLRGIA 693
+M + +HPN++ L GV T+ P IITEFM G+L +LR N + + L+ M I+
Sbjct: 175 VMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVSAVVLLYMATQIS 234
Query: 694 TGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGGKIPVRWT 753
+ M+YL + N+IHRDLAARN LV + K+ADFGLSR + T D G K P++WT
Sbjct: 235 SAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLM--TGDTYTAHAGAKFPIKWT 292
Query: 754 APEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCPE 813
APE++A+ KF+ SDVW+ G++ WE+ ++G PY V + +EK YR+ P CPE
Sbjct: 293 APESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPE 352
Query: 814 AVYQLMLDCWQKERTHRPTFSSIVKTLDKLIR 845
VY+LM CWQ + RP+F+ I + + + +
Sbjct: 353 KVYELMRACWQWNPSDRPSFAEIHQAFETMFQ 384
>UniRef50_Q5IJ68 Cluster: Trk-like receptor tyrosine kinase; n=1;
Aplysia californica|Rep: Trk-like receptor tyrosine
kinase - Aplysia californica (California sea hare)
Length = 865
Score = 212 bits (517), Expect = 4e-53
Identities = 127/336 (37%), Positives = 189/336 (56%), Gaps = 32/336 (9%)
Query: 561 TYEDPN--QAVREFAREIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLK 618
TY P+ A R +E+ A C+T+ ++G G FG V RG+L+ A G VA+K LK
Sbjct: 273 TYFSPSGASARRHAVQEVPADCLTLIEVVGEGAFGQVFRGELR-SAEGGACHQVAVKVLK 331
Query: 619 PGSTERARRDFLAEASIMGQFEHPNVIFLQGVVTKC---NPIMIITEFMENGSLDTFLRA 675
G++ A DF E IM F+H N++ L G+V + P M+ E+ME+G L LR
Sbjct: 332 DGASPDAHEDFEREVEIMSAFDHDNILKLLGIVVQGVEGAPYMVF-EYMEHGDLSELLRR 390
Query: 676 NDGKFRVLQ----------LVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQ-----L 720
ND R LV + IATGM+YL+ ++HRDLA RN LV + L
Sbjct: 391 NDPHLRSADSKTFRLNKSDLVEISVQIATGMRYLAAQRFVHRDLATRNCLVGTAPPGAGL 450
Query: 721 VCKIADFGLSREIESTADGAYTTRGGK-IPVRWTAPEAIAFRKFTSASDVWSMGIVCWEV 779
+ KI+DFG+SR+I + + Y G + +P+RW +PEAI + +FT SDVW+ G+V WE+
Sbjct: 451 LVKISDFGMSRDIYT--NDYYKIGGSRMLPIRWMSPEAIKYGRFTCESDVWAYGVVLWEI 508
Query: 780 MSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKT 839
S+G +PY+ SN++VI +++G L P DCP VY +ML CW+ + R F ++K
Sbjct: 509 FSYGRQPYFGHSNEEVIHFLDQGILLQRPEDCPSTVYHVMLGCWKGDPRQRIVFDRLLKY 568
Query: 840 L----DKLIRCPDTLRKIAQNRSADPLA--GDTPDL 869
L D+L + P +++ +R A GD+P +
Sbjct: 569 LTDYRDRLNK-PTHCQQMPMSRPVADCAQLGDSPSV 603
>UniRef50_UPI0000F1EB7D Cluster: PREDICTED: hypothetical protein;
n=3; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 510
Score = 211 bits (516), Expect = 6e-53
Identities = 112/276 (40%), Positives = 161/276 (58%), Gaps = 13/276 (4%)
Query: 575 EIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEAS 634
E+ T+E +G G F DV RGK K ++VAIK LK S R+F+ E
Sbjct: 237 ELPKEEFTLEEELGKGFFADVYRGKWK------GMVNVAIKILKNDSINH--REFMLETQ 288
Query: 635 IMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRANDGK-FRVLQLVGMLRGIA 693
I+ + H ++I L V T +P IITE ME G L + L+ +G+ L M +A
Sbjct: 289 ILKKLRHKHLIALFAVCTSSSPFYIITELMEKGDLLSLLKGKEGQDLNAQMLTEMASQVA 348
Query: 694 TGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGGKIPVRWT 753
GM YL E N IHRDLAARNVLV + +CK+AD GL+R ++ + Y++ +IP +W+
Sbjct: 349 DGMAYLEEQNSIHRDLAARNVLVGANYICKVADLGLARIVK---ESVYSSEDAQIPYKWS 405
Query: 754 APEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCPE 813
APEAI+ +F++ SDVWS G++ +E+ ++G PY +SN +V I GYR+PAP +CP
Sbjct: 406 APEAISHGRFSNKSDVWSFGVLLYEMFTYGGVPYPAFSNIEVYNMITSGYRMPAPPNCPS 465
Query: 814 AVYQLMLDCWQKERTHRPTFSSIVKTL-DKLIRCPD 848
+Y +ML CW+ RP FS +++ L D C D
Sbjct: 466 HIYDIMLMCWRYSAEERPDFSELLRLLEDYCAPCTD 501
>UniRef50_P10447 Cluster: Tyrosine-protein kinase transforming
protein Abl; n=57; root|Rep: Tyrosine-protein kinase
transforming protein Abl - Feline sarcoma virus (strain
Hardy-Zuckerman 2)
Length = 439
Score = 211 bits (515), Expect = 8e-53
Identities = 112/264 (42%), Positives = 164/264 (62%), Gaps = 12/264 (4%)
Query: 575 EIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEAS 634
E++ + IT++ +GGG++G+V G K + + VA+KTLK + E +FL EA+
Sbjct: 185 EMERTDITMKHKLGGGQYGEVYEGVWKKYS-----LTVAVKTLKEDTMEV--EEFLKEAA 237
Query: 635 IMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLR-ANDGKFRVLQLVGMLRGIA 693
+M + +HPN++ L GV T+ P IITEFM G+L +LR N + + L+ M I+
Sbjct: 238 VMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQIS 297
Query: 694 TGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGG-KIPVRW 752
+ M+YL + N+IHRDLAARN LV + K+ADFGLSR + T D YT G K P++W
Sbjct: 298 SAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLM--TGD-TYTAHAGTKFPIKW 354
Query: 753 TAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCP 812
TAPE++A+ KF+ SDVW+ G++ WE+ ++G PY V + +EK YR+ P CP
Sbjct: 355 TAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCP 414
Query: 813 EAVYQLMLDCWQKERTHRPTFSSI 836
E VY+LM CWQ + RP F+ I
Sbjct: 415 EKVYELMRACWQWNPSDRPAFAEI 438
>UniRef50_Q7YZX2 Cluster: Bruton's tyrosine kinase-like protein;
n=1; Suberites domuncula|Rep: Bruton's tyrosine
kinase-like protein - Suberites domuncula (Sponge)
Length = 700
Score = 210 bits (514), Expect = 1e-52
Identities = 114/273 (41%), Positives = 156/273 (57%), Gaps = 13/273 (4%)
Query: 573 AREIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAE 632
A EID +++ +G G+FG V GK K +IDVAIK ++ G+ DF+ E
Sbjct: 425 AWEIDKVSLSLGKELGSGQFGRVVSGKWK------GKIDVAIKMMREGAMNED--DFIEE 476
Query: 633 ASIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFRVLQLV-GMLRG 691
A +M QF+H N++ L GV TK PI I+ E M NG L FLR +++ M
Sbjct: 477 AKVMKQFQHENLVKLYGVCTKNGPIFIVQELMVNGCLLQFLRQRKELVEKTEIILDMATQ 536
Query: 692 IATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYT-TRGGKIPV 750
I + M+YL E +IHRDLAARN LV + V K+ADFGL+R + D YT + G K P+
Sbjct: 537 ICSAMKYLEESGFIHRDLAARNCLVGERNVVKVADFGLARFV---VDDEYTASEGTKFPI 593
Query: 751 RWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMD 810
+W APE I KF+S SDVWS GI+ WE+ + G+ PY ++N V+ + GYRL P
Sbjct: 594 KWAAPEVITHAKFSSKSDVWSFGILLWELWTGGKTPYPTFTNSQVLDEVLMGYRLDRPKQ 653
Query: 811 CPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKL 843
CP VY LM CW RP F ++ +L ++
Sbjct: 654 CPPEVYALMGKCWLTNSDDRPQFKTLSSSLGQM 686
>UniRef50_P51451 Cluster: Tyrosine-protein kinase BLK; n=5;
Euteleostomi|Rep: Tyrosine-protein kinase BLK - Homo
sapiens (Human)
Length = 505
Score = 210 bits (514), Expect = 1e-52
Identities = 114/270 (42%), Positives = 164/270 (60%), Gaps = 16/270 (5%)
Query: 575 EIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEAS 634
EI + + +G G+FG+V G K + VAIKTLK G+ + FL EA+
Sbjct: 235 EIPRQSLRLVRKLGSGQFGEVWMGYYK------NNMKVAIKTLKEGTM--SPEAFLGEAN 286
Query: 635 IMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRANDG-KFRVLQLVGMLRGIA 693
+M +H ++ L VVTK PI I+TE+M G L FL+ ++G + + +L+ M IA
Sbjct: 287 VMKALQHERLVRLYAVVTK-EPIYIVTEYMARGCLLDFLKTDEGSRLSLPRLIDMSAQIA 345
Query: 694 TGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTR-GGKIPVRW 752
GM Y+ MN IHRDL A N+LV+ L CKIADFGL+R I+S YT + G K P++W
Sbjct: 346 EGMAYIERMNSIHRDLRAANILVSEALCCKIADFGLARIIDSE----YTAQEGAKFPIKW 401
Query: 753 TAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCP 812
TAPEAI F FT +DVWS G++ EV+++G PY SN +VI+++E+GYR+P P CP
Sbjct: 402 TAPEAIHFGVFTIKADVWSFGVLLMEVVTYGRVPYPGMSNPEVIRNLERGYRMPRPDTCP 461
Query: 813 EAVYQ-LMLDCWQKERTHRPTFSSIVKTLD 841
+Y+ ++ +CW+ RPTF + L+
Sbjct: 462 PELYRGVIAECWRSRPEERPTFEFLQSVLE 491
>UniRef50_Q4S351 Cluster: Chromosome 4 SCAF14752, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 4 SCAF14752, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 810
Score = 210 bits (513), Expect = 1e-52
Identities = 108/276 (39%), Positives = 159/276 (57%), Gaps = 9/276 (3%)
Query: 566 NQAVREFAREIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERA 625
N V++ ++ + + ++G G FG+V +G L+ + VA+KT K
Sbjct: 537 NPVVKDKKWILNHEDVVLGELLGKGNFGEVFKGTLQRDKT-----PVAVKTCKEDLPSEL 591
Query: 626 RRDFLAEASIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFRVLQL 685
+ FL+EA I+ Q++HPN++ L GV T+ PI I+ E + G ++LR + + QL
Sbjct: 592 KIRFLSEARILKQYDHPNIVKLIGVCTQRQPIYIVMELVPGGDFLSYLRKKKDELKTKQL 651
Query: 686 VGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRG 745
+ A GM YL N IHRDLAARN LV KI+DFG+SR+ + DG Y++ G
Sbjct: 652 LRFAVDAAAGMAYLESKNCIHRDLAARNCLVGDNNALKISDFGMSRQED---DGIYSSSG 708
Query: 746 GK-IPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYR 804
K IP++WTAPEA+ + +++S SDVWS GI+ WE S G PY +NQ + +EKGYR
Sbjct: 709 LKQIPIKWTAPEALNYGRYSSESDVWSYGILLWETFSLGMCPYPGMTNQQAREQVEKGYR 768
Query: 805 LPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTL 840
+ P CP+ VY++M CWQ RP FS + + L
Sbjct: 769 MACPQRCPDDVYKVMQRCWQYNPEDRPKFSELQRDL 804
>UniRef50_Q9Y1Y2 Cluster: Protein tyrosine kinase; n=1; Ephydatia
fluviatilis|Rep: Protein tyrosine kinase - Ephydatia
fluviatilis
Length = 743
Score = 210 bits (513), Expect = 1e-52
Identities = 108/259 (41%), Positives = 154/259 (59%), Gaps = 5/259 (1%)
Query: 585 AIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEASIMGQFEHPNV 644
A +G GEFG V +G K + G +I+VA+KTL+ S ++F EA IM HP +
Sbjct: 469 AELGQGEFGSVLKGLYK--GADGKKIEVAVKTLRLDSQGHGEKEFAREAGIMVTLNHPCI 526
Query: 645 IFLQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFR-VLQLVGMLRGIATGMQYLSEMN 703
+ L G+ T P+M++ E + G+L +L VL L IA+GM YL
Sbjct: 527 VKLIGI-TNGKPMMMVQELISMGALVDYLYERKQPIPDVLTLKLWAAEIASGMMYLETKR 585
Query: 704 YIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGGKIPVRWTAPEAIAFRKF 763
++HRDLAARN+LV S KI+DFGLSR + + +D ++GG+ PV+W APE+I F F
Sbjct: 586 FVHRDLAARNILVQSMKQVKISDFGLSRAVGANSDYYKASQGGRWPVKWYAPESINFGTF 645
Query: 764 TSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEK-GYRLPAPMDCPEAVYQLMLDC 822
+ ASDVWS GI WE+ SFG+ PY + + +V+ +E YRL P DCP ++Y+LML C
Sbjct: 646 SHASDVWSYGITLWEMFSFGDAPYGDMTGAEVLDRVENLNYRLECPRDCPSSIYELMLRC 705
Query: 823 WQKERTHRPTFSSIVKTLD 841
W E RPTF+ + + +
Sbjct: 706 WSLEPNERPTFAQLYDSFE 724
>UniRef50_O76978 Cluster: Tyrosine kinase; n=1; Sycon raphanus|Rep:
Tyrosine kinase - Sycon raphanus
Length = 879
Score = 210 bits (512), Expect = 2e-52
Identities = 112/263 (42%), Positives = 157/263 (59%), Gaps = 12/263 (4%)
Query: 581 ITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEASIMGQFE 640
I I IG G FGDV +G LK ++VA+K+ + ++ FL EA I+ Q+
Sbjct: 620 ILIGEKIGKGNFGDVFKGYLKTH-----NMEVAVKSCRSEDFPDKQK-FLQEAEILKQYR 673
Query: 641 HPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRANDGK-FRVLQLVGMLRGIATGMQYL 699
HPN++ L GV + P+ II E M G+ +FLR +GK +V L M A GM +L
Sbjct: 674 HPNIVELIGVCAEKEPLYIIMELMAGGNFLSFLRGPEGKRLKVNNLTEMCVEAAAGMVFL 733
Query: 700 SEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGG--KIPVRWTAPEA 757
+ N IHRDLAARN LV V KI+DFG+SRE + DG YT G +IP++WT+PEA
Sbjct: 734 EQRNCIHRDLAARNCLVGDNNVLKISDFGMSREED---DGIYTVSSGLKQIPIKWTSPEA 790
Query: 758 IAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEAVYQ 817
+ + ++T+ SDVWS GI+ WE ++G PY +N++ + IE YR+P P CP VY+
Sbjct: 791 LNYGRYTTQSDVWSYGILLWETYTYGSGPYPGMNNRETRERIESNYRMPRPELCPHPVYK 850
Query: 818 LMLDCWQKERTHRPTFSSIVKTL 840
LML CW+ + RP+F+ I L
Sbjct: 851 LMLSCWEYDPDKRPSFAEIYDKL 873
>UniRef50_Q16XX9 Cluster: Tyrosine-protein kinase shark; n=2;
Culicidae|Rep: Tyrosine-protein kinase shark - Aedes
aegypti (Yellowfever mosquito)
Length = 939
Score = 209 bits (510), Expect = 3e-52
Identities = 114/289 (39%), Positives = 166/289 (57%), Gaps = 7/289 (2%)
Query: 576 IDASCITIEAIIGGGEFGDVCRGKLKL--PASCGPEIDVAIKTLKPGSTERARRDFLAEA 633
I CI + ++G GEFG V +G L+ P+ C P +AIK L + +R R DFL EA
Sbjct: 653 IPKECILTQKVLGRGEFGYVYQGLLRPQEPSDCTP---IAIKQLVESTGKRNRVDFLREA 709
Query: 634 SIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFRV-LQLVGMLRGI 692
S+M + H ++ L G+ K P+M++ E + GS+ ++ AN G L+LV I
Sbjct: 710 SVMIRLRHHCIVKLIGIC-KGPPLMMVEELVPLGSMLDYIIANKGTINPKLELVIWAAQI 768
Query: 693 ATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGGKIPVRW 752
A GMQYL + +++HRDLAARN+L+ S+ KI+DFGLSR I + D ++GGK P++W
Sbjct: 769 ACGMQYLEQHHFVHRDLAARNILLASRNQAKISDFGLSRAIGAGDDYYRASQGGKWPIKW 828
Query: 753 TAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCP 812
APE+ + F+ ASDVWS G+ WE+ S G PY + DVIK IE G RL P CP
Sbjct: 829 YAPESFNYGTFSHASDVWSFGVTMWEMYSLGAPPYQDMKGVDVIKLIENGQRLSQPDLCP 888
Query: 813 EAVYQLMLDCWQKERTHRPTFSSIVKTLDKLIRCPDTLRKIAQNRSADP 861
E V+++M +CW RPTF + + I+ + + + +P
Sbjct: 889 ENVFEVMKNCWNYNPKSRPTFKFLTRFFTDDIKYQNLQELVQSGKEINP 937
>UniRef50_Q06187 Cluster: Tyrosine-protein kinase BTK; n=54;
Gnathostomata|Rep: Tyrosine-protein kinase BTK - Homo
sapiens (Human)
Length = 659
Score = 209 bits (510), Expect = 3e-52
Identities = 108/267 (40%), Positives = 155/267 (58%), Gaps = 12/267 (4%)
Query: 575 EIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEAS 634
EID +T +G G+FG V GK + + DVAIK +K GS + +F+ EA
Sbjct: 396 EIDPKDLTFLKELGTGQFGVVKYGKWR------GQYDVAIKMIKEGSM--SEDEFIEEAK 447
Query: 635 IMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFRVLQLVGMLRGIAT 694
+M H ++ L GV TK PI IITE+M NG L +LR +F+ QL+ M + +
Sbjct: 448 VMMNLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLREMRHRFQTQQLLEMCKDVCE 507
Query: 695 GMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTR-GGKIPVRWT 753
M+YL ++HRDLAARN LVN Q V K++DFGLSR + D YT+ G K PVRW+
Sbjct: 508 AMEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGLSRYV---LDDEYTSSVGSKFPVRWS 564
Query: 754 APEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCPE 813
PE + + KF+S SD+W+ G++ WE+ S G+ PY ++N + + I +G RL P E
Sbjct: 565 PPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLYRPHLASE 624
Query: 814 AVYQLMLDCWQKERTHRPTFSSIVKTL 840
VY +M CW ++ RPTF ++ +
Sbjct: 625 KVYTIMYSCWHEKADERPTFKILLSNI 651
>UniRef50_P03949 Cluster: Tyrosine-protein kinase abl-1; n=5;
Caenorhabditis|Rep: Tyrosine-protein kinase abl-1 -
Caenorhabditis elegans
Length = 1224
Score = 209 bits (510), Expect = 3e-52
Identities = 114/271 (42%), Positives = 157/271 (57%), Gaps = 10/271 (3%)
Query: 575 EIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEAS 634
E+D S I + +GGG++GDV G K + +A+K LK + +FLAEA+
Sbjct: 305 ELDRSEIIMHNKLGGGQYGDVYEGYWKRH-----DCTIAVKALKEDAMPL--HEFLAEAA 357
Query: 635 IMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFRV-LQLVGMLRGIA 693
IM H N++ L GV T P IITEFM NG+L +LR D + LV M IA
Sbjct: 358 IMKDLHHKNLVRLLGVCTHEAPFYIITEFMCNGNLLEYLRRTDKSLLPPIILVQMASQIA 417
Query: 694 TGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGGKIPVRWT 753
+GM YL ++IHRDLAARN LV+ + KIADFGL+R ++ A+ G K P++WT
Sbjct: 418 SGMSYLEARHFIHRDLAARNCLVSEHNIVKIADFGLARFMKEDTYTAHA--GAKFPIKWT 475
Query: 754 APEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCPE 813
APE +AF F+S SDVW+ G++ WE+ ++G PY +V +E G+R+ P CP
Sbjct: 476 APEGLAFNTFSSKSDVWAFGVLLWEIATYGMAPYPGVELSNVYGLLENGFRMDGPQGCPP 535
Query: 814 AVYQLMLDCWQKERTHRPTFSSIVKTLDKLI 844
+VY+LML CW + RP F I L+ LI
Sbjct: 536 SVYRLMLQCWNWSPSDRPRFRDIHFNLENLI 566
>UniRef50_Q5MCM8 Cluster: Protein-tyrosine kinase; n=2;
Anthomedusae|Rep: Protein-tyrosine kinase - Hydractinia
echinata (Snail fur) (Hermit crab hydroid)
Length = 1162
Score = 208 bits (508), Expect = 5e-52
Identities = 109/275 (39%), Positives = 161/275 (58%), Gaps = 10/275 (3%)
Query: 575 EIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRD------ 628
E+ +T++ IIG G+FGDV +G K S EI VA+KT K ++ + D
Sbjct: 423 EVARDDLTLDEIIGQGQFGDVYQGTFKSKIS-SVEIPVAVKTYKI-ELDKEQEDGTRAEK 480
Query: 629 FLAEASIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFRVLQLVGM 688
FL EA +M QF+HP+VI L G+V+ +P II E G L ++L+ + +L+
Sbjct: 481 FLEEAYLMQQFDHPHVIKLIGIVSD-SPSYIIMELASYGELRSYLQQYRTQTESERLLTY 539
Query: 689 LRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGGKI 748
+ ++T + YL N++HRD+AARN+L K+ADFGLSR I+ Y GK+
Sbjct: 540 IYQLSTALSYLESRNFVHRDIAARNILAADPHTIKLADFGLSRWIDEE-QSYYKASKGKL 598
Query: 749 PVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAP 808
P++W APE+I FR+F+SASDVW G+ CWE++ +G +P+ N+ VI IE G RLP P
Sbjct: 599 PIKWMAPESINFRRFSSASDVWMFGVCCWEILMYGVKPFQGVPNEKVIGKIENGERLPLP 658
Query: 809 MDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKL 843
+C +Y LM + W E + RPTF + L ++
Sbjct: 659 PNCAPTLYHLMTESWHYEPSKRPTFQELKSRLSQI 693
>UniRef50_Q52V39 Cluster: Tyrosine-protein kinase receptor; n=2;
Branchiostoma floridae|Rep: Tyrosine-protein kinase
receptor - Branchiostoma floridae (Florida lancelet)
(Amphioxus)
Length = 797
Score = 207 bits (505), Expect = 1e-51
Identities = 117/303 (38%), Positives = 172/303 (56%), Gaps = 21/303 (6%)
Query: 560 HTYEDPN--QAVREFA-REIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKT 616
H E+PN + +E R I I +G G FG V GK + VA+KT
Sbjct: 486 HVVENPNYFRDSKELVIRHIQRDTIHFVGELGEGAFGRVYLGKCEKLKPDEDASLVAVKT 545
Query: 617 LKPGSTERARRDFLAEASIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRAN 676
LK S E AR+DF EA ++ +H N++ GV T+ P ++I E+MENG L+ +LR++
Sbjct: 546 LKEMSVEDARKDFDREAELLTNMQHENIVKFYGVCTEGEPWLMIFEYMENGDLNNYLRSH 605
Query: 677 --DGKFRV--------LQLVGMLR---GIATGMQYLSEMNYIHRDLAARNVLVNSQLVCK 723
D F + L +V +L+ +A+G++Y++ +++HRDLA RN LV +LV K
Sbjct: 606 GPDAAFLIKNPATHKELSIVELLQISVQVASGVEYMASQHFVHRDLATRNCLVGDKLVVK 665
Query: 724 IADFGLSREIESTADGAYTTRGGK--IPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMS 781
I DFG+SR+I ST Y GG +PVRW PE++ +RKFT SD+WS G+V WE+ +
Sbjct: 666 IGDFGMSRDIYSTD---YYRVGGHTMLPVRWMPPESVLYRKFTIESDIWSFGVVLWEIFT 722
Query: 782 FGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLD 841
FG++P++ +N +VI+ I G L P CP V LML CW+K R I K L
Sbjct: 723 FGKQPWYELANHEVIECITSGRLLGCPRGCPRNVRALMLGCWKKTPAQRTNIQDIHKKLK 782
Query: 842 KLI 844
+++
Sbjct: 783 EML 785
>UniRef50_Q170Z1 Cluster: Tyrosine-protein kinase receptor; n=1; Aedes
aegypti|Rep: Tyrosine-protein kinase receptor - Aedes
aegypti (Yellowfever mosquito)
Length = 2073
Score = 207 bits (505), Expect = 1e-51
Identities = 108/264 (40%), Positives = 158/264 (59%), Gaps = 14/264 (5%)
Query: 581 ITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEASIMGQFE 640
+T +G G FG+V G +K E VAIKTL+ G+TE+ + +FL EA +M F+
Sbjct: 1812 MTSSPFLGSGAFGEVYEGIVK-GVGGEAETRVAIKTLRKGATEQEKAEFLQEAHLMSNFK 1870
Query: 641 HPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRAN------DGKFRVLQLVGMLRGIAT 694
H +++ L GV + + I+ E M+ G L ++LR+N +L L+ M +AT
Sbjct: 1871 HKHILKLIGVCLDLDSLYIVMELMQGGDLLSYLRSNRPTPGNPSMLTLLDLISMCVDVAT 1930
Query: 695 GMQYLSEMNYIHRDLAARNVLVNS----QLVCKIADFGLSREIESTADGAYTTRG-GKIP 749
G +YL EM+++HRDLA RN LV+S + V KI DFGL+R+I + Y G G +P
Sbjct: 1931 GCRYLEEMHFVHRDLACRNCLVSSMDPRERVVKIGDFGLARDIYK--NDYYRKEGEGLLP 1988
Query: 750 VRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPM 809
VRW +PE++ FTS SD+W+ G++ WE+M+ G++PY +N +V+ + G RL P
Sbjct: 1989 VRWMSPESLVDGVFTSQSDIWAFGVLLWEIMTLGQQPYPARNNVEVLHYVRDGGRLTRPQ 2048
Query: 810 DCPEAVYQLMLDCWQKERTHRPTF 833
DCPE +YQLML CW RPTF
Sbjct: 2049 DCPEELYQLMLKCWSYSPEDRPTF 2072
>UniRef50_P00528 Cluster: Tyrosine-protein kinase Src64B; n=6;
Endopterygota|Rep: Tyrosine-protein kinase Src64B -
Drosophila melanogaster (Fruit fly)
Length = 552
Score = 206 bits (504), Expect = 2e-51
Identities = 114/263 (43%), Positives = 161/263 (61%), Gaps = 15/263 (5%)
Query: 575 EIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEAS 634
EI S I + +G G FG+V GK + IDVA+KTL+ G+ A FL EA+
Sbjct: 278 EIPRSEIQLLRKLGRGNFGEVFYGKWR------NSIDVAVKTLREGTMSTAA--FLQEAA 329
Query: 635 IMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFRVLQ-LVGMLRGIA 693
IM +F H ++ L V ++ PI I+ E+M GSL FLR DG++ + L+ + +A
Sbjct: 330 IMKKFRHNRLVALYAVCSQEEPIYIVQEYMSKGSLLDFLREGDGRYLHFEDLIYIATQVA 389
Query: 694 TGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTR-GGKIPVRW 752
+GM+YL IHRDLAARNVL+ V KI DFGL+R I AD Y + G + PV+W
Sbjct: 390 SGMEYLESKQLIHRDLAARNVLIGENNVAKICDFGLARVI---ADDEYCPKQGSRFPVKW 446
Query: 753 TAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMD-- 810
TAPEAI + KF+ SDVWS GI+ E+ ++G+ PY +++VI++IE+G+R+P P +
Sbjct: 447 TAPEAIIYGKFSIKSDVWSYGILLMELFTYGQVPYPGMHSREVIENIERGFRMPKPTNHY 506
Query: 811 CPEAVYQLMLDCWQKERTHRPTF 833
P+ +YQL+L CW RPTF
Sbjct: 507 FPDNIYQLLLQCWDAVPEKRPTF 529
>UniRef50_Q7Z1D3 Cluster: Focal adhesion kinase; n=1; Lytechinus
variegatus|Rep: Focal adhesion kinase - Lytechinus
variegatus (Sea urchin)
Length = 1006
Score = 206 bits (502), Expect = 3e-51
Identities = 108/288 (37%), Positives = 163/288 (56%), Gaps = 10/288 (3%)
Query: 557 IDPHTYEDPNQAVREFAREIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKT 616
+D Y P E +RE+ +T+ IG G+FGDV +G + +++VA+KT
Sbjct: 418 VDDDDYAMPAAKDYEISREL----VTLVETIGQGQFGDVHKG---IYIDQDEKVEVAVKT 470
Query: 617 LKPGSTERARRDFLAEASIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRAN 676
K ST+ FL EA IM QF+HP++I L GV T PI I+ E G + FL+ +
Sbjct: 471 CKVESTQALGERFLEEAYIMKQFDHPHIIKLIGVCTD-PPIWIVMELAPFGEMRMFLQTH 529
Query: 677 DGKFRVLQLVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIEST 736
+ + L+ ++ + YL ++HRD+AARN+LV ++ K+ DFGLSR +
Sbjct: 530 KEELTLASLILYAYQLSMALSYLESKKFVHRDIAARNLLVVAKDNVKLGDFGLSRLLHDH 589
Query: 737 ADGAYTTRGGKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVI 796
+ Y GK+P++W APE+I FR+FTSASDVW G+ WE++ +G +P+ N +VI
Sbjct: 590 S--YYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMYGVKPFQGVKNNEVI 647
Query: 797 KSIEKGYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLI 844
IE G RLP P CP +Y +M CW E + RP F + L++++
Sbjct: 648 GRIENGERLPMPAACPPTLYSVMTLCWSYEPSKRPNFKDLKTRLNEIL 695
>UniRef50_O77440 Cluster: Protein-tyrosine kinase HTK98; n=1; Hydra
vulgaris|Rep: Protein-tyrosine kinase HTK98 - Hydra
attenuata (Hydra) (Hydra vulgaris)
Length = 624
Score = 206 bits (502), Expect = 3e-51
Identities = 106/284 (37%), Positives = 160/284 (56%), Gaps = 5/284 (1%)
Query: 553 SRTYIDPHTYEDPNQAVREFAREIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDV 612
S+ + +++P + +E E+D + +E +G G FG V +G L + + V
Sbjct: 330 SKDIVKKEGFKNPFET-QERETELDPKRLRLEHELGHGNFGSVVKGVYLLKNN--KSVAV 386
Query: 613 AIKTLKPGSTERARRDFLAEASIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTF 672
A+KTLK + + + EA IM + +HPN++ L GV T+ M++ E G L F
Sbjct: 387 AVKTLKEEDIPGQKSEIVKEAEIMSKLDHPNIVRLIGV-TQSPGFMLVMELAPQGPLHKF 445
Query: 673 LRANDGKFRVLQLVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSRE 732
L+ N VL ++ ++ + GM YL +++HRDLAARNVLV S+ KI+DFG+SR
Sbjct: 446 LKKNRN-MNVLDILVLMLQVDEGMNYLESQHFVHRDLAARNVLVVSENFVKISDFGMSRA 504
Query: 733 IESTADGAYTTRGGKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSN 792
+ + R GK P++W APE I + KF+S DVWS GI WE +S+G +PY
Sbjct: 505 MGVGNEYYRAERAGKWPLKWYAPECIYYHKFSSKGDVWSYGITMWEAVSYGGKPYQGMRG 564
Query: 793 QDVIKSIEKGYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSI 836
+++ +E GYRLP P +C +AVY LML CW+ RP+F I
Sbjct: 565 PVIVEKLESGYRLPKPDNCSDAVYTLMLKCWETNPDDRPSFMEI 608
>UniRef50_UPI0000D569CE Cluster: PREDICTED: similar to CG10023-PA,
isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG10023-PA, isoform A - Tribolium castaneum
Length = 1106
Score = 205 bits (501), Expect = 4e-51
Identities = 103/270 (38%), Positives = 156/270 (57%), Gaps = 4/270 (1%)
Query: 575 EIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEAS 634
E+ I + I+G G+FGDV +G K A G I VA+KT K + FL EA
Sbjct: 422 ELQRDQIQLGEILGEGQFGDVHKGTYK--AKDGSLIPVAVKTCKREADLNTTEKFLEEAY 479
Query: 635 IMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFRVLQLVGMLRGIAT 694
IM +F+H ++I L GV ++ +P+ I+ E + G L +L+ N + L+ ++T
Sbjct: 480 IMQKFDHQHIIKLIGVCSE-SPVWIVMELAKLGELRAYLQNNKDDLDLATLLLYAFQLST 538
Query: 695 GMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGGKIPVRWTA 754
+ YL ++HRD+AARNVLV+S K+ DFGLSR + Y GK+P++W +
Sbjct: 539 ALSYLESKKFVHRDIAARNVLVSSHTSVKLGDFGLSRSMNDD-QSYYKASKGKLPIKWMS 597
Query: 755 PEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEA 814
PE+I FR+FT ASDVW G+ WE++ +G +P+ N +V+ IE G RL P +CP
Sbjct: 598 PESINFRRFTIASDVWMFGVCMWEILMYGIKPFQGVKNNEVLTKIENGERLALPPNCPPR 657
Query: 815 VYQLMLDCWQKERTHRPTFSSIVKTLDKLI 844
+Y LM CW E + RP+F I + L++++
Sbjct: 658 LYSLMSQCWSYEPSKRPSFKEIKEILNEIL 687
>UniRef50_UPI00015A7C25 Cluster: UPI00015A7C25 related cluster; n=3;
Danio rerio|Rep: UPI00015A7C25 UniRef100 entry - Danio
rerio
Length = 759
Score = 205 bits (501), Expect = 4e-51
Identities = 109/267 (40%), Positives = 154/267 (57%), Gaps = 17/267 (6%)
Query: 587 IGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEAS-IMGQFEHPNVI 645
IG G FG+V G+L+ VA+K + + FL EA+ I+ Q++HPN++
Sbjct: 497 IGRGNFGEVFSGRLR-----SDNTPVAVKACRENLPAEHKNKFLMEAARILKQYDHPNIV 551
Query: 646 FLQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFRVLQLVGMLRGIATGMQYLSEMNYI 705
L GV T+ PI II E ++ G TFLR + L+ M +A+G+ YL I
Sbjct: 552 KLIGVCTQKQPIYIIMELVQGGDFLTFLRTEGHNLKSSMLIRMAENVASGLAYLESKKCI 611
Query: 706 HRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGG--KIPVRWTAPEAIAF--- 760
HRD+AARN LV + V KI+DFG+SRE + DG Y+ GG +IPV+WTAPEA+ +
Sbjct: 612 HRDVAARNCLVGEESVVKISDFGMSREEQ---DGVYSATGGMKQIPVKWTAPEALNYGSP 668
Query: 761 RKFTSASDVWSMGIVCWEVMSFGERPY---WNWSNQDVIKSIEKGYRLPAPMDCPEAVYQ 817
++T+ SDVWS G++ WE S G PY SNQ +E+GYR+PAP +CP+ +Y
Sbjct: 669 GRYTTESDVWSFGVLLWETFSRGVTPYTIPTVMSNQQTRDEVERGYRMPAPNNCPDEIYT 728
Query: 818 LMLDCWQKERTHRPTFSSIVKTLDKLI 844
LM CWQ + RP+F + L L+
Sbjct: 729 LMCQCWQYDPRKRPSFLKLKADLGALL 755
>UniRef50_Q4RY69 Cluster: Chromosome 3 SCAF14978, whole genome
shotgun sequence; n=3; Fungi/Metazoa group|Rep:
Chromosome 3 SCAF14978, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 958
Score = 205 bits (500), Expect = 5e-51
Identities = 104/271 (38%), Positives = 152/271 (56%), Gaps = 6/271 (2%)
Query: 575 EIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEAS 634
+I I + I+G G FG+V G K G + VAIKT K S + + FL+EAS
Sbjct: 381 KISRDDIIVGQILGEGFFGEVHNGVYK--TQTGENLSVAIKTCKNCSAD-VKEKFLSEAS 437
Query: 635 IMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFRVLQLVGMLRGIAT 694
+M +HP+++ L GV+ + +P+ I+ E E+G L +L + L+ I
Sbjct: 438 VMKNLDHPHIVRLIGVI-EADPVWIVMELYEHGELGKYLVEQQYSLTTVMLITYCLQICK 496
Query: 695 GMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGGKIPVRWTA 754
+ YL +N +HRD+A RN+LV S L K+ DFGLSR IE + Y ++P++W A
Sbjct: 497 ALAYLEGLNVVHRDIAVRNILVASPLCVKLGDFGLSRYIEE--EEYYKASASRLPIKWMA 554
Query: 755 PEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEA 814
PE+I FR+FT+ASDVW G+ WE+ S ++P++ N VI +E G RLP P CP
Sbjct: 555 PESINFRRFTTASDVWMFGVCVWEIFSMAQQPFFWLENSQVIDQLESGIRLPKPQLCPPT 614
Query: 815 VYQLMLDCWQKERTHRPTFSSIVKTLDKLIR 845
VY L+ CW E RP FS + +L ++ R
Sbjct: 615 VYSLVSSCWSHEPHLRPQFSHLACSLSEIHR 645
>UniRef50_Q9Y1Y9 Cluster: Protein tyrosine kinase; n=3; Metazoa|Rep:
Protein tyrosine kinase - Ephydatia fluviatilis
Length = 2069
Score = 205 bits (500), Expect = 5e-51
Identities = 120/310 (38%), Positives = 181/310 (58%), Gaps = 23/310 (7%)
Query: 571 EFAREIDASCITIEAIIGGGEFGDVCRGKLK--LPASCGPEIDVAIKTLKPGSTERARRD 628
E ++ + +E I GEFG+V +G L GP I VA+KTL+ G+ ++
Sbjct: 1692 ELLQKFPRGNLKLENFIDRGEFGEVFQGTATDILGPGTGP-IPVAVKTLRKGAIIEEQKK 1750
Query: 629 FLAEASIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFR------- 681
FLAEA++MG F HPN++ + GV + +P+ II E M G L FLR D K
Sbjct: 1751 FLAEAALMGNFNHPNIVKVLGVCVENDPVYIIMELMPGGDLLHFLR--DAKVERGPPLLT 1808
Query: 682 VLQLVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQ---LVCKIADFGLSREIESTAD 738
V +L+ + +A G YL + ++IHRDLAARN LV+S+ V KI DFGL++++ S+
Sbjct: 1809 VKELIQIALDVAQGCHYLQQTHFIHRDLAARNCLVSSKGADRVVKIGDFGLAKDLYSS-- 1866
Query: 739 GAYTTRGG-KIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIK 797
Y G K+PVRW APEA+ KF SDVWS G++ WE+M+FG +PY +NQ+V++
Sbjct: 1867 DYYQVEGQRKLPVRWMAPEALLQGKFNMESDVWSFGVLMWEIMTFGNQPYPALNNQEVLQ 1926
Query: 798 SIEKGYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLIRCPDTLRK--IAQ 855
+ RL P +CP +YQLM +CW+K + R F I + L+ + + LR+ ++
Sbjct: 1927 FVTAEGRLQKPENCPGKIYQLMQNCWKKVASERLHFDVIKEILNNYL---EHLRRDSVSS 1983
Query: 856 NRSADPLAGD 865
+ +D +AG+
Sbjct: 1984 DGDSDDMAGN 1993
>UniRef50_Q9Y1Y6 Cluster: Protein tyrosine kinase; n=1; Ephydatia
fluviatilis|Rep: Protein tyrosine kinase - Ephydatia
fluviatilis
Length = 948
Score = 205 bits (500), Expect = 5e-51
Identities = 107/285 (37%), Positives = 161/285 (56%), Gaps = 18/285 (6%)
Query: 575 EIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEAS 634
E+D + E +G G FG V + + VA+K LK G++ + +++F EA+
Sbjct: 611 EVDRDKVRYEGDLGQGHFGLVVKATALGVVPGRDQCIVAVKILKEGASLQTKKEFFHEAA 670
Query: 635 IMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFRVLQL--------- 685
+M F+HPN++ L GV + P+ +I EFM+ G L+ FLR N K++
Sbjct: 671 LMHSFDHPNIVKLIGVCVEQEPLCMIFEFMQLGDLNNFLRHNSPKWQESSASCAKYGGPK 730
Query: 686 --------VGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTA 737
V M I G+ YL++ +YIHRDLA RN LV+ L KI+DFGLS++I ST
Sbjct: 731 CDITTPIQVAMSLDITAGLAYLADNHYIHRDLATRNCLVSGDLRIKISDFGLSQDIYST- 789
Query: 738 DGAYTTRGGKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIK 797
D ++ +P+RW PEAI F +FT+ SDVWS+G+V WE+ S+G +PY++ SN+ VI
Sbjct: 790 DYCRLSQSELLPIRWMPPEAILFARFTTQSDVWSLGVVLWELFSYGIQPYYSMSNEQVIA 849
Query: 798 SIEKGYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDK 842
+ G + P CP +Y LM+DCW + RPT + + L +
Sbjct: 850 HVRDGNVMNCPDGCPSEIYDLMVDCWNMDPGQRPTAADVNVALQR 894
>UniRef50_Q9Y1Y1 Cluster: Protein tyrosine kinase; n=2; cellular
organisms|Rep: Protein tyrosine kinase - Ephydatia
fluviatilis
Length = 893
Score = 205 bits (500), Expect = 5e-51
Identities = 109/260 (41%), Positives = 154/260 (59%), Gaps = 14/260 (5%)
Query: 587 IGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRD-FLAEASIMGQFEHPNVI 645
+G G FGDV LK VA+KT + ST+ R+ FL EA I+ Q++HPN++
Sbjct: 640 LGKGAFGDVWEAALKGQGK------VAVKTCR--STDVPDREKFLQEAEILKQYDHPNIV 691
Query: 646 FLQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFRVLQLVGMLRGIATGMQYLSEMNYI 705
L GV P++I+ E M GSL +LR + +L+ M GM+YL N I
Sbjct: 692 KLIGVSWDTEPVLIVMELMPGGSLLDYLRKKAAQMTKGKLLHMSIDACGGMEYLESKNCI 751
Query: 706 HRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGG--KIPVRWTAPEAIAFRKF 763
HRDLAARN LV + KI+DFG+SRE E G YT + G +IP++WTAPEA+ + ++
Sbjct: 752 HRDLAARNCLVGENDIVKISDFGMSREEEG---GMYTVQSGTRQIPIKWTAPEALNYGRY 808
Query: 764 TSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEAVYQLMLDCW 823
TSASDVWS G++ +EV S G PY SN + ++ GYR+P P CP ++Q+M CW
Sbjct: 809 TSASDVWSFGVLLYEVFSGGSTPYPGMSNAETRTQVDSGYRMPPPQGCPAEIHQIMQLCW 868
Query: 824 QKERTHRPTFSSIVKTLDKL 843
+ RP F +++++L KL
Sbjct: 869 AYDAEDRPKFGAVLESLKKL 888
>UniRef50_Q0PDJ5 Cluster: Protein tyrosine kinase CSK; n=1; Monosiga
ovata|Rep: Protein tyrosine kinase CSK - Monosiga ovata
Length = 468
Score = 205 bits (500), Expect = 5e-51
Identities = 112/277 (40%), Positives = 163/277 (58%), Gaps = 16/277 (5%)
Query: 570 REFAR-EIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRD 628
R+F EI I A IG G+FGDV G + G + VAIKTLK + A
Sbjct: 203 RKFVNWEISPREIVKSAQIGSGQFGDVFEGLYR-----GQK--VAIKTLKDVQGD-AIDQ 254
Query: 629 FLAEASIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRAND-GKFRVLQLVG 687
FL EA M + H N++ L GV T+ +PIMI++EFM G L +LR+ + +G
Sbjct: 255 FLLEADTMTRLRHKNLVQLIGVCTQGSPIMIVSEFMGKGCLLDYLRSRGRAVINLATQLG 314
Query: 688 MLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGGK 747
R I M+YL E ++HRDLAARN+L++ V K+ADFGL+++ + T GK
Sbjct: 315 FCRDICAAMEYLEEQKFVHRDLAARNILLSDDGVAKVADFGLAKDSQLGV-----TDIGK 369
Query: 748 IPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPA 807
+P++WTAPEAI + TS SDVWS G+V WE+ +FG PY ++V+ ++ KGYR+
Sbjct: 370 LPIKWTAPEAIRLKVSTSKSDVWSFGVVLWEIFAFGRAPYPRMGQKEVVDAVVKGYRMEC 429
Query: 808 PMDCPEAVY-QLMLDCWQKERTHRPTFSSIVKTLDKL 843
P CP+ VY ++M+ CW+ + RPTF ++++ L +
Sbjct: 430 PDTCPKEVYDKIMMACWEIDPVKRPTFKTLMRALSSI 466
>UniRef50_P08922 Cluster: Proto-oncogene tyrosine-protein kinase ROS
precursor; n=20; Eumetazoa|Rep: Proto-oncogene
tyrosine-protein kinase ROS precursor - Homo sapiens
(Human)
Length = 2347
Score = 204 bits (499), Expect = 7e-51
Identities = 115/269 (42%), Positives = 158/269 (58%), Gaps = 15/269 (5%)
Query: 581 ITIEAIIGGGEFGDVCRGKLKLPASCGP-EIDVAIKTLKPGSTERARRDFLAEASIMGQF 639
+T+ ++G G FG+V G G EI VA+KTLK GST++ + +FL EA +M +F
Sbjct: 1945 LTLRLLLGSGAFGEVYEGTAVDILGVGSGEIKVAVKTLKKGSTDQEKIEFLKEAHLMSKF 2004
Query: 640 EHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLR-ANDGKF-----RVLQLVGMLRGIA 693
HPN++ GV P II E ME G L T+LR A F ++ LV + I+
Sbjct: 2005 NHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMATFYGPLLTLVDLVDLCVDIS 2064
Query: 694 TGMQYLSEMNYIHRDLAARNVLVN-----SQLVCKIADFGLSREIESTADGAYTTRG-GK 747
G YL M++IHRDLAARN LV+ S + KI DFGL+R+I + Y RG G
Sbjct: 2065 KGCVYLERMHFIHRDLAARNCLVSVKDYTSPRIVKIGDFGLARDIYK--NDYYRKRGEGL 2122
Query: 748 IPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPA 807
+PVRW APE++ FT+ SDVWS GI+ WE+++ G +PY SN DV+ ++ G RL
Sbjct: 2123 LPVRWMAPESLMDGIFTTQSDVWSFGILIWEILTLGHQPYPAHSNLDVLNYVQTGGRLEP 2182
Query: 808 PMDCPEAVYQLMLDCWQKERTHRPTFSSI 836
P +CP+ ++ LM CW +E RPTF I
Sbjct: 2183 PRNCPDDLWNLMTQCWAQEPDQRPTFHRI 2211
>UniRef50_Q7YZH7 Cluster: MBRTK2; n=1; Monosiga brevicollis|Rep:
MBRTK2 - Monosiga brevicollis
Length = 759
Score = 204 bits (498), Expect = 9e-51
Identities = 112/278 (40%), Positives = 154/278 (55%), Gaps = 11/278 (3%)
Query: 575 EIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEAS 634
E++ + + +G G FG V R S G E A K LKPG+ RAR+DFL+E +
Sbjct: 354 EVERRSVRLGEKLGNGAFGQVFRAWFCNRHS-GEERSCAAKALKPGAPFRARQDFLSEMT 412
Query: 635 IMGQF-EHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLR---ANDGKFRVL---QLVG 687
+M + HPN+I + G + P +++ E E G+L +LR + K ++L QL
Sbjct: 413 VMKEIGAHPNIIGIFGHCLRDEPHILLVELAELGNLRDYLRKCRTSQSKPQLLGSRQLAD 472
Query: 688 MLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGGK 747
IA+GM +L N IHRDLAARNVL++ L CKI DFGL+R IE+ Y T K
Sbjct: 473 FCLQIASGMSFLERKNVIHRDLAARNVLLSQSLACKICDFGLARSIENED---YETTATK 529
Query: 748 IPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPA 807
+PV+W APE++ +R +TS SDVWS G+ WE+ S G PY N D++ + GYRLP
Sbjct: 530 LPVKWMAPESLGYRIYTSKSDVWSFGVTMWEIFSLGGTPYVKHRNVDILSLLADGYRLPK 589
Query: 808 PMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLIR 845
P P + CW E +RPTF +V L IR
Sbjct: 590 PRQAPGQADAIARMCWMHEADNRPTFLELVDLLTAFIR 627
>UniRef50_Q8WRF4 Cluster: Receptor tyrosine kinase; n=1; Monosiga
brevicollis|Rep: Receptor tyrosine kinase - Monosiga
brevicollis
Length = 1476
Score = 203 bits (496), Expect = 2e-50
Identities = 109/277 (39%), Positives = 156/277 (56%), Gaps = 11/277 (3%)
Query: 575 EIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEAS 634
E+D C+ + +G G FG+V + ++ S G A KTLKP + R+DFL+E +
Sbjct: 720 EVDRQCVRLGEELGHGAFGEVFQAWIRNSYS-GKVRRCAAKTLKPDVSFEHRQDFLSEMT 778
Query: 635 IMGQF-EHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRA------NDGKFRVLQLVG 687
+M + HPNVI + G + P +++ E E G++ +LR N RV Q+
Sbjct: 779 VMKEIGAHPNVIGIIGHCLRETPQILLVELAEFGNMRDYLRGCRATQENPQTIRVDQMAD 838
Query: 688 MLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGGK 747
IA GM +L + N IHRDLAARNVLV+ CKI+DFGL+R IE G Y T K
Sbjct: 839 FCLQIARGMAFLEQKNVIHRDLAARNVLVDKNFECKISDFGLARSIEG---GEYKTTATK 895
Query: 748 IPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPA 807
+PV+W APE++ R +T+ SDVWS G+ WE+ S G PY N+DV+ +E G+RLP+
Sbjct: 896 LPVKWMAPESLKSRIYTTKSDVWSFGVTMWEIFSLGGTPYKEHQNRDVLSFLESGHRLPS 955
Query: 808 PMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLI 844
P P + CW E + RP+FS +V L ++
Sbjct: 956 PRQAPVEFDDIARMCWVLEASDRPSFSELVDLLADIV 992
>UniRef50_Q14289 Cluster: Protein tyrosine kinase 2 beta; n=47;
Euteleostomi|Rep: Protein tyrosine kinase 2 beta - Homo
sapiens (Human)
Length = 1009
Score = 203 bits (495), Expect = 2e-50
Identities = 110/297 (37%), Positives = 168/297 (56%), Gaps = 9/297 (3%)
Query: 581 ITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEASIMGQFE 640
+ + I+G G FG+V G G +I+VA+KT K T + F++EA IM +
Sbjct: 425 VVLNRILGEGFFGEVYEGVYTNHK--GEKINVAVKTCKKDCTLDNKEKFMSEAVIMKNLD 482
Query: 641 HPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFRVLQLVGMLRGIATGMQYLS 700
HP+++ L G++ + P II E G L +L N +VL LV I M YL
Sbjct: 483 HPHIVKLIGIIEE-EPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYLE 541
Query: 701 EMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGGKIPVRWTAPEAIAF 760
+N +HRD+A RN+LV S K+ DFGLSR IE + Y ++P++W +PE+I F
Sbjct: 542 SINCVHRDIAVRNILVASPECVKLGDFGLSRYIED--EDYYKASVTRLPIKWMSPESINF 599
Query: 761 RKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEAVYQLML 820
R+FT+ASDVW + WE++SFG++P++ N+DVI +EKG RLP P CP +Y LM
Sbjct: 600 RRFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMT 659
Query: 821 DCWQKERTHRPTFSSIVKTLDKLIRCPDTLRKIAQNRSADPLAGDTPDLIQFTSVEE 877
CW + + RP F+ +V +L + + + + Q R+A TP +++ T+ +E
Sbjct: 660 RCWDYDPSDRPRFTELVCSLSDVYQMEKDI-AMEQERNA---RYRTPKILEPTAFQE 712
>UniRef50_P42684 Cluster: Tyrosine-protein kinase ABL2; n=38;
Euteleostomi|Rep: Tyrosine-protein kinase ABL2 - Homo
sapiens (Human)
Length = 1182
Score = 203 bits (495), Expect = 2e-50
Identities = 107/282 (37%), Positives = 165/282 (58%), Gaps = 10/282 (3%)
Query: 575 EIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEAS 634
E++ + IT++ +GGG++G+V G K + + VA+KTLK + E +FL EA+
Sbjct: 282 EMERTDITMKHKLGGGQYGEVYVGVWKKYS-----LTVAVKTLKEDTMEV--EEFLKEAA 334
Query: 635 IMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLR-ANDGKFRVLQLVGMLRGIA 693
+M + +HPN++ L GV T P I+TE+M G+L +LR N + + L+ M I+
Sbjct: 335 VMKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLRECNREEVTAVVLLYMATQIS 394
Query: 694 TGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGGKIPVRWT 753
+ M+YL + N+IHRDLAARN LV V K+ADFGLSR + T D G K P++WT
Sbjct: 395 SAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLM--TGDTYTAHAGAKFPIKWT 452
Query: 754 APEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCPE 813
APE++A+ F+ SDVW+ G++ WE+ ++G PY V +EKGYR+ P CP
Sbjct: 453 APESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRMEQPEGCPP 512
Query: 814 AVYQLMLDCWQKERTHRPTFSSIVKTLDKLIRCPDTLRKIAQ 855
VY+LM CW+ RP+F+ + + + ++A+
Sbjct: 513 KVYELMRACWKWSPADRPSFAETHQAFETMFHDSSISEEVAE 554
>UniRef50_Q7YSY1 Cluster: Fes-like tyrosine kinase protein; n=1;
Schistosoma mansoni|Rep: Fes-like tyrosine kinase protein
- Schistosoma mansoni (Blood fluke)
Length = 1259
Score = 202 bits (494), Expect = 3e-50
Identities = 112/263 (42%), Positives = 150/263 (57%), Gaps = 11/263 (4%)
Query: 575 EIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTER-ARRDFLAEA 633
E+D + + IG G FGDV RG C +VA+KT + T RR FL
Sbjct: 955 ELDNRDVQLLQKIGQGNFGDVYRGVYN---GC----EVAVKTCRVDMTASDLRRKFLQGE 1007
Query: 634 SIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFRVLQLVGMLRGIA 693
+ F HPN++ L G+ + PIMI+ E++ GSL LR + V++L+ M A
Sbjct: 1008 TTALNFNHPNIVKLVGIAVQSYPIMIVMEYVPGGSLLNHLRKSKNALPVMKLLQMSLDAA 1067
Query: 694 TGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGGKIPVRWT 753
GM YL N IHRDLAARN L++ KIADFG+SRE E + + + G+IP++WT
Sbjct: 1068 NGMMYLEARNCIHRDLAARNCLISDDGQLKIADFGMSRE-EHIYE--LSDKRGQIPIKWT 1124
Query: 754 APEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCPE 813
APEA+ ++T DVWS G++ WE+ +FG+ PY NWSNQ IE GYRLPAP P
Sbjct: 1125 APEALRTGRYTIKCDVWSYGVLLWEIFTFGDVPYRNWSNQQTRDMIESGYRLPAPDLMPV 1184
Query: 814 AVYQLMLDCWQKERTHRPTFSSI 836
+ LM CW E +RP+FS I
Sbjct: 1185 WLRTLMNHCWHDEPMNRPSFSKI 1207
>UniRef50_Q16620 Cluster: BDNF/NT-3 growth factors receptor
precursor; n=73; Gnathostomata|Rep: BDNF/NT-3 growth
factors receptor precursor - Homo sapiens (Human)
Length = 822
Score = 202 bits (494), Expect = 3e-50
Identities = 115/334 (34%), Positives = 183/334 (54%), Gaps = 22/334 (6%)
Query: 529 VYTGPDRPAKTSSNATTPLFAGTGSRTYIDPHTYEDPNQAVRE--FAREIDASCITIEAI 586
+ G + P+ + + T +P + N ++ F + I I ++
Sbjct: 484 ISNGSNTPSSSEGGPDAVIIGMTKIPVIENPQYFGITNSQLKPDTFVQHIKRHNIVLKRE 543
Query: 587 IGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEASIMGQFEHPNVIF 646
+G G FG V + +I VA+KTLK S + AR+DF EA ++ +H +++
Sbjct: 544 LGEGAFGKVFLAECYNLCPEQDKILVAVKTLKDAS-DNARKDFHREAELLTNLQHEHIVK 602
Query: 647 LQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFRVL-------------QLVGMLRGIA 693
GV + +P++++ E+M++G L+ FLRA+ G VL Q++ + + IA
Sbjct: 603 FYGVCVEGDPLIMVFEYMKHGDLNKFLRAH-GPDAVLMAEGNPPTELTQSQMLHIAQQIA 661
Query: 694 TGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGGK--IPVR 751
GM YL+ +++HRDLA RN LV L+ KI DFG+SR++ ST Y GG +P+R
Sbjct: 662 AGMVYLASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDVYSTD---YYRVGGHTMLPIR 718
Query: 752 WTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDC 811
W PE+I +RKFT+ SDVWS+G+V WE+ ++G++P++ SN +VI+ I +G L P C
Sbjct: 719 WMPPESIMYRKFTTESDVWSLGVVLWEIFTYGKQPWYQLSNNEVIECITQGRVLQRPRTC 778
Query: 812 PEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLIR 845
P+ VY+LML CWQ+E R I L L +
Sbjct: 779 PQEVYELMLGCWQREPHMRKNIKGIHTLLQNLAK 812
>UniRef50_P43403 Cluster: Tyrosine-protein kinase ZAP-70; n=55;
Euteleostomi|Rep: Tyrosine-protein kinase ZAP-70 - Homo
sapiens (Human)
Length = 619
Score = 202 bits (493), Expect = 4e-50
Identities = 114/312 (36%), Positives = 173/312 (55%), Gaps = 11/312 (3%)
Query: 526 NGEVYTGPDRPAKTSSNATTPLFAGTGSRTYIDPHTYEDPNQAVREFAREIDASCITIEA 585
N + YT P+ TS + P+ T Y P++ + + + F + + IE
Sbjct: 288 NSDGYT-PEPARITSPDKPRPMPMDTS--VYESPYSDPEELKDKKLFLKRDNLLIADIE- 343
Query: 586 IIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEASIMGQFEHPNVI 645
+G G FG V +G ++ +IDVAIK LK G+ + + + EA IM Q ++P ++
Sbjct: 344 -LGCGNFGSVRQGVYRMRKK---QIDVAIKVLKQGTEKADTEEMMREAQIMHQLDNPYIV 399
Query: 646 FLQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFRVLQLVGMLRGIATGMQYLSEMNYI 705
L GV + +M++ E G L FL + V + +L ++ GM+YL E N++
Sbjct: 400 RLIGVC-QAEALMLVMEMAGGGPLHKFLVGKREEIPVSNVAELLHQVSMGMKYLEEKNFV 458
Query: 706 HRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTR-GGKIPVRWTAPEAIAFRKFT 764
HRDLAARNVL+ ++ KI+DFGLS+ + D YT R GK P++W APE I FRKF+
Sbjct: 459 HRDLAARNVLLVNRHYAKISDFGLSKAL-GADDSYYTARSAGKWPLKWYAPECINFRKFS 517
Query: 765 SASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEAVYQLMLDCWQ 824
S SDVWS G+ WE +S+G++PY +V+ IE+G R+ P +CP +Y LM DCW
Sbjct: 518 SRSDVWSYGVTMWEALSYGQKPYKKMKGPEVMAFIEQGKRMECPPECPPELYALMSDCWI 577
Query: 825 KERTHRPTFSSI 836
+ RP F ++
Sbjct: 578 YKWEDRPDFLTV 589
>UniRef50_UPI0000DB7330 Cluster: PREDICTED: similar to Ack
CG14992-PA; n=1; Apis mellifera|Rep: PREDICTED: similar
to Ack CG14992-PA - Apis mellifera
Length = 1302
Score = 202 bits (492), Expect = 5e-50
Identities = 107/282 (37%), Positives = 160/282 (56%), Gaps = 6/282 (2%)
Query: 581 ITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEASIMGQFE 640
+T+ +G G FG V RG+ P+ G ++ VA+K LK + +F++E +M +
Sbjct: 110 VTLSDQLGDGSFGIVRRGEWTSPS--GRKLPVAVKVLKADAQPSVIENFVSEVQVMHTLD 167
Query: 641 HPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFRVLQLVGMLRGIATGMQYLS 700
H N+I L GVV P+M++TE G+L +LR G+ VL L +ATGM YL
Sbjct: 168 HQNLIRLYGVVLS-QPMMMVTELASLGALLDYLRKQCGQISVLTLCDYALQVATGMAYLE 226
Query: 701 EMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGGKIPVRWTAPEAIAF 760
++HRDLA RNVL++S KI DFGL R + D + K+P W APE++
Sbjct: 227 AKRFLHRDLACRNVLLSSIDKVKIGDFGLMRALPQQEDCYVMSEHKKVPFPWCAPESLKR 286
Query: 761 RKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEK-GYRLPAPMDCPEAVYQLM 819
RKFT ASDVW G+ WE+++FGE P+ ++++ I+K G RL P P +YQLM
Sbjct: 287 RKFTHASDVWMFGVTLWEMLTFGEEPWVGLKGSEILRKIDKEGERLHEPEATPPEMYQLM 346
Query: 820 LDCWQKERTHRPTFSSIVKTLDKLIRCPDTLRKIAQNRSADP 861
L CW + + RPTF+S+ +L ++ P ++ I+ +DP
Sbjct: 347 LRCWACDPSERPTFASLRVSLTSMV--PTVMKAISSFAVSDP 386
>UniRef50_Q9U531 Cluster: Focal adhesion kinase homolog DFak56;
n=15; Sophophora|Rep: Focal adhesion kinase homolog
DFak56 - Drosophila melanogaster (Fruit fly)
Length = 1200
Score = 202 bits (492), Expect = 5e-50
Identities = 114/292 (39%), Positives = 160/292 (54%), Gaps = 24/292 (8%)
Query: 575 EIDASCITIEAIIGGGEFGDVCRGKLKLP---------------------ASCGPE-IDV 612
E+D S IT A IG G+FGDV G LP A P+ I V
Sbjct: 451 ELDRSLITPSAKIGVGQFGDVYVGTYTLPKLGKGKNLAGNGKNSNSDQRNADSRPDVIQV 510
Query: 613 AIKTLKPGSTERARRDFLAEASIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTF 672
AIKT K +FLAEA IM +F+HP++I L G+ + PI I+ E + G L +
Sbjct: 511 AIKTCKANDDPEKTENFLAEAYIMQKFDHPHIIRLIGICSVM-PIWIVMELAKLGELRAY 569
Query: 673 LRANDGKFRVLQLVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSRE 732
L+ N + L+ ++T + YL ++HRD+AARNVLV+S K+ADFGLSR
Sbjct: 570 LKTNSERLSHGTLLKYCYQLSTALSYLESKKFVHRDIAARNVLVSSPTCVKLADFGLSRW 629
Query: 733 IESTADGAYTTRGGKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSN 792
+ S ++T +P++W +PE+I FR+FT+ASDVW G+ WE++ G +P+ N
Sbjct: 630 V-SDQSYYHSTPTVALPIKWMSPESINFRRFTTASDVWMFGVCIWEILMLGVKPFQGVKN 688
Query: 793 QDVIKSIEKGYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLI 844
DVI +E G RLP P +CP +Y LM CW E RP F I +TL +++
Sbjct: 689 SDVILKLENGERLPLPPNCPPRLYSLMSQCWAYEPLKRPNFKRIKETLHEIL 740
>UniRef50_Q4H3N2 Cluster: Epidermal growth factor receptor; n=1;
Ciona intestinalis|Rep: Epidermal growth factor receptor
- Ciona intestinalis (Transparent sea squirt)
Length = 878
Score = 202 bits (492), Expect = 5e-50
Identities = 114/287 (39%), Positives = 164/287 (57%), Gaps = 10/287 (3%)
Query: 565 PNQAVREFAREIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPE---IDVAIKTLKPGS 621
PNQA +E + + I I+G G FG V +G +P E + VAIK L+ S
Sbjct: 110 PNQAQLRIVKEAE---LRIGKILGSGAFGTVHKGYW-IPDLAPRERVKVPVAIKVLRDES 165
Query: 622 TERARRDFLAEASIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFR 681
++ A + L EA +M EHPN++ L G+ + IM+IT+ M G+L ++R N
Sbjct: 166 SQVASNEILDEAFVMASCEHPNLVRLLGI-SLSQRIMLITQLMPLGNLLEYVRDNKDNIG 224
Query: 682 VLQLVGMLRGIATGMQYLSEMNY-IHRDLAARNVLVNSQLVCKIADFGLSREIESTADGA 740
L+ IA GM+YLSE + +HRDLAARNVLV S +I DFGL++ ++ D
Sbjct: 225 SQHLLNWSLQIAKGMKYLSEEKHLVHRDLAARNVLVKSPNHVRITDFGLAKLLDVKED-V 283
Query: 741 YTTRGGKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIE 800
Y GGK+P++W A E+I R FT SDVWS G+ WE+M+FG++PY + ++V +E
Sbjct: 284 YRAEGGKMPIKWLALESIQHRIFTQKSDVWSFGVTMWELMTFGKKPYESVPAREVHTLLE 343
Query: 801 KGYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLIRCP 847
+G RLP P C +Y L++ CW + RPTF + + L KL R P
Sbjct: 344 RGERLPQPYICTIDIYMLLIKCWTVDAEARPTFKELTEELSKLARDP 390
>UniRef50_P41240 Cluster: Tyrosine-protein kinase CSK; n=21;
Deuterostomia|Rep: Tyrosine-protein kinase CSK - Homo
sapiens (Human)
Length = 450
Score = 202 bits (492), Expect = 5e-50
Identities = 117/292 (40%), Positives = 169/292 (57%), Gaps = 21/292 (7%)
Query: 557 IDPHTYEDPNQAVREFARE---IDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVA 613
I P E A EF R ++ + + IG GEFGDV G + G + VA
Sbjct: 168 IKPKVMEGTVAAQDEFYRSGWALNMKELKLLQTIGKGEFGDVMLGDYR-----GNK--VA 220
Query: 614 IKTLKPGSTERARRDFLAEASIMGQFEHPNVIFLQGVVTK-CNPIMIITEFMENGSLDTF 672
+K +K +T +A FLAEAS+M Q H N++ L GV+ + + I+TE+M GSL +
Sbjct: 221 VKCIKNDATAQA---FLAEASVMTQLRHSNLVQLLGVIVEEKGGLYIVTEYMAKGSLVDY 277
Query: 673 LRANDGKFRVLQ-LVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSR 731
LR+ L+ + M+YL N++HRDLAARNVLV+ V K++DFGL++
Sbjct: 278 LRSRGRSVLGGDCLLKFSLDVCEAMEYLEGNNFVHRDLAARNVLVSEDNVAKVSDFGLTK 337
Query: 732 EIESTADGAYTTRGGKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWS 791
E ST D GK+PV+WTAPEA+ +KF++ SDVWS GI+ WE+ SFG PY
Sbjct: 338 EASSTQDT------GKLPVKWTAPEALREKKFSTKSDVWSFGILLWEIYSFGRVPYPRIP 391
Query: 792 NQDVIKSIEKGYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKL 843
+DV+ +EKGY++ AP CP AVY++M +CW + RP+F + + L+ +
Sbjct: 392 LKDVVPRVEKGYKMDAPDGCPPAVYEVMKNCWHLDAAMRPSFLQLREQLEHI 443
>UniRef50_Q9H3Y6 Cluster: Tyrosine-protein kinase Srms; n=17;
Amniota|Rep: Tyrosine-protein kinase Srms - Homo sapiens
(Human)
Length = 488
Score = 201 bits (491), Expect = 6e-50
Identities = 112/284 (39%), Positives = 160/284 (56%), Gaps = 13/284 (4%)
Query: 565 PNQAVREFAREIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTER 624
P +A R+ E S + +G G FG+V G L L + + VAIK +K S
Sbjct: 214 PQKAPRQDVWERPHSEFALGRKLGEGYFGEVWEG-LWLGS-----LPVAIKVIK--SANM 265
Query: 625 ARRDFLAEASIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRANDGK-FRVL 683
D E + H +I L V + P+ I+TE M G+L FL +G+ R+
Sbjct: 266 KLTDLAKEIQTLKGLRHERLIRLHAVCSGGEPVYIVTELMRKGNLQAFLGTPEGRALRLP 325
Query: 684 QLVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYT- 742
L+G +A GM YL E +HRDLAARNVLV+ L CK+ADFGL+R ++ D Y+
Sbjct: 326 PLLGFACQVAEGMSYLEEQRVVHRDLAARNVLVDDGLACKVADFGLARLLK---DDIYSP 382
Query: 743 TRGGKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKG 802
+ KIPV+WTAPEA +R F+ SDVWS G++ EV ++G+ PY +N + ++ I +G
Sbjct: 383 SSSSKIPVKWTAPEAANYRVFSQKSDVWSFGVLLHEVFTYGQCPYEGMTNHETLQQIMRG 442
Query: 803 YRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLIRC 846
YRLP P CP VY LML+CW+ RP+F+++ + L + RC
Sbjct: 443 YRLPRPAACPAEVYVLMLECWRSSPEERPSFATLREKLHAIHRC 486
>UniRef50_Q01973 Cluster: Tyrosine-protein kinase transmembrane
receptor ROR1 precursor; n=21; Euteleostomi|Rep:
Tyrosine-protein kinase transmembrane receptor ROR1
precursor - Homo sapiens (Human)
Length = 937
Score = 201 bits (491), Expect = 6e-50
Identities = 109/280 (38%), Positives = 157/280 (56%), Gaps = 18/280 (6%)
Query: 573 AREIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAE 632
A+E+ S + +G FG + +G L LP ++ VAIKTLK + + +F E
Sbjct: 465 AKELPLSAVRFMEELGECAFGKIYKGHLYLPGMDHAQL-VAIKTLKDYNNPQQWTEFQQE 523
Query: 633 ASIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFL------------RANDGKF 680
AS+M + HPN++ L G VT+ P+ ++ E++ G L FL DG
Sbjct: 524 ASLMAELHHPNIVCLLGAVTQEQPVCMLFEYINQGDLHEFLIMRSPHSDVGCSSDEDGTV 583
Query: 681 RVL----QLVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIEST 736
+ + + IA GM+YLS ++H+DLAARN+L+ QL KI+D GLSREI S
Sbjct: 584 KSSLDHGDFLHIAIQIAAGMEYLSSHFFVHKDLAARNILIGEQLHVKISDLGLSREIYS- 642
Query: 737 ADGAYTTRGGKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVI 796
AD +P+RW PEAI + KF+S SD+WS G+V WE+ SFG +PY+ +SNQ+VI
Sbjct: 643 ADYYRVQSKSLLPIRWMPPEAIMYGKFSSDSDIWSFGVVLWEIFSFGLQPYYGFSNQEVI 702
Query: 797 KSIEKGYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSI 836
+ + K LP DCP +Y LM +CW + + RP F I
Sbjct: 703 EMVRKRQLLPCSEDCPPRMYSLMTECWNEIPSRRPRFKDI 742
>UniRef50_Q91987 Cluster: BDNF/NT-3 growth factors receptor
precursor; n=17; Euteleostomi|Rep: BDNF/NT-3 growth
factors receptor precursor - Gallus gallus (Chicken)
Length = 818
Score = 201 bits (490), Expect = 8e-50
Identities = 115/334 (34%), Positives = 182/334 (54%), Gaps = 22/334 (6%)
Query: 529 VYTGPDRPAKTSSNATTPLFAGTGSRTYIDPHTYEDPNQAVRE--FAREIDASCITIEAI 586
+ G + P+ + + T +P + N ++ F + I I ++
Sbjct: 480 ISNGSNTPSSSEGGPDAVIIGMTKIPVIENPQYFGITNSQLKPDTFVQHIKRHNIVLKRE 539
Query: 587 IGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEASIMGQFEHPNVIF 646
+G G FG V + +I VA+KTLK S + AR+DF EA ++ +H +++
Sbjct: 540 LGEGAFGKVFLAECYNLCPEQDKILVAVKTLKDAS-DNARKDFHREAELLTNLQHEHIVK 598
Query: 647 LQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFRVL-------------QLVGMLRGIA 693
GV + +P++++ E+M++G L+ FLRA+ G VL Q++ + + IA
Sbjct: 599 FYGVCVEGDPLIMVFEYMKHGDLNKFLRAH-GPDAVLMAEGNRPAELTQSQMLHIAQQIA 657
Query: 694 TGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGGK--IPVR 751
GM YL+ +++HRDLA RN LV L+ KI DFG+SR++ ST Y GG +P+R
Sbjct: 658 AGMVYLASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDVYSTD---YYRVGGHTMLPIR 714
Query: 752 WTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDC 811
W PE+I +RKFT+ SDVWS+G+V WE+ ++G++P++ SN +VI+ I +G L P C
Sbjct: 715 WMPPESIMYRKFTTESDVWSLGVVLWEIFTYGKQPWYQLSNNEVIECITQGRVLQRPRTC 774
Query: 812 PEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLIR 845
P+ VY LML CWQ+E R I L L +
Sbjct: 775 PKEVYDLMLGCWQREPHMRLNIKEIHSLLQNLAK 808
>UniRef50_Q08881 Cluster: Tyrosine-protein kinase ITK/TSK; n=18;
Euteleostomi|Rep: Tyrosine-protein kinase ITK/TSK - Homo
sapiens (Human)
Length = 620
Score = 201 bits (490), Expect = 8e-50
Identities = 109/269 (40%), Positives = 155/269 (57%), Gaps = 12/269 (4%)
Query: 576 IDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEASI 635
ID S +T IG G+FG V G + VAIKT++ G+ + DF+ EA +
Sbjct: 358 IDPSELTFVQEIGSGQFGLVHLGYWL------NKDKVAIKTIREGAM--SEEDFIEEAEV 409
Query: 636 MGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFRVLQLVGMLRGIATG 695
M + HP ++ L GV + PI ++ EFME+G L +LR G F L+GM + G
Sbjct: 410 MMKLSHPKLVQLYGVCLEQAPICLVFEFMEHGCLSDYLRTQRGLFAAETLLGMCLDVCEG 469
Query: 696 MQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGG-KIPVRWTA 754
M YL E IHRDLAARN LV V K++DFG++R + D YT+ G K PV+W +
Sbjct: 470 MAYLEEACVIHRDLAARNCLVGENQVIKVSDFGMTRFV---LDDQYTSSTGTKFPVKWAS 526
Query: 755 PEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEA 814
PE +F +++S SDVWS G++ WEV S G+ PY N SN +V++ I G+RL P
Sbjct: 527 PEVFSFSRYSSKSDVWSFGVLMWEVFSEGKIPYENRSNSEVVEDISTGFRLYKPRLASTH 586
Query: 815 VYQLMLDCWQKERTHRPTFSSIVKTLDKL 843
VYQ+M CW++ RP FS +++ L ++
Sbjct: 587 VYQIMNHCWKERPEDRPAFSRLLRQLAEI 615
>UniRef50_P08630 Cluster: Tyrosine-protein kinase Btk29A; n=10;
Endopterygota|Rep: Tyrosine-protein kinase Btk29A -
Drosophila melanogaster (Fruit fly)
Length = 786
Score = 200 bits (489), Expect = 1e-49
Identities = 101/257 (39%), Positives = 154/257 (59%), Gaps = 14/257 (5%)
Query: 587 IGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEASIMGQFEHPNVIF 646
+G G+FG V RGK + ID A+K +K G+ + DF+ EA +M + +HPN++
Sbjct: 532 LGSGQFGVVRRGKWR------GSIDTAVKMMKEGTM--SEDDFIEEAKVMTKLQHPNLVQ 583
Query: 647 LQGVVTKCNPIMIITEFMENGSLDTFLRANDGKF--RVLQLVGMLRGIATGMQYLSEMNY 704
L GV +K PI I+TE+M++GSL +LR ++ + L+ M ++ GM YL NY
Sbjct: 584 LYGVCSKHRPIYIVTEYMKHGSLLNYLRRHEKTLIGNMGLLLDMCIQVSKGMTYLERHNY 643
Query: 705 IHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGG-KIPVRWTAPEAIAFRKF 763
IHRDLAARN LV S+ V K+ADFGL+R + D YT+ GG K P++W PE + + +F
Sbjct: 644 IHRDLAARNCLVGSENVVKVADFGLARYV---LDDQYTSSGGTKFPIKWAPPEVLNYTRF 700
Query: 764 TSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEAVYQLMLDCW 823
+S SDVW+ G++ WE+ + G+ PY N +V++ +++G L P C + +Y +M CW
Sbjct: 701 SSKSDVWAYGVLMWEIFTCGKMPYGRLKNTEVVERVQRGIILEKPKSCAKEIYDVMKLCW 760
Query: 824 QKERTHRPTFSSIVKTL 840
RP F ++ L
Sbjct: 761 SHGPEERPAFRVLMDQL 777
>UniRef50_UPI00015A61DF Cluster: UPI00015A61DF related cluster; n=2;
Danio rerio|Rep: UPI00015A61DF UniRef100 entry - Danio
rerio
Length = 985
Score = 200 bits (488), Expect = 1e-49
Identities = 101/262 (38%), Positives = 155/262 (59%), Gaps = 6/262 (2%)
Query: 576 IDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEASI 635
I + I + I+G G FG+V G K + G ++VA+KT K S + + F++EA I
Sbjct: 357 ISRNDIVLGRILGEGFFGEVHDGIYK--SKSGERVNVAVKTCKDCSAD-VKEKFMSEALI 413
Query: 636 MGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFRVLQLVGMLRGIATG 695
M + +HP+++ L G++ + +P+ I+ E G L+ +L+ N K + L+ I+
Sbjct: 414 MKKLDHPHIVRLIGIIEE-DPVWIVMELYPFGELENYLKDNQNKLTNVTLILYSLQISKA 472
Query: 696 MQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGGKIPVRWTAP 755
+ YL +N +HRD+A RNVLV K+ DFGLSR IE + Y ++P++W AP
Sbjct: 473 LAYLEGVNMVHRDIAVRNVLVAKVDCVKLGDFGLSRYIEE--EEYYKASVTRLPIKWMAP 530
Query: 756 EAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEAV 815
E+I FR+FTSASDVW + WE+MS G++P++ N+DVI +E+G RLP P CP +
Sbjct: 531 ESINFRRFTSASDVWMFAVCMWEIMSGGQQPFFWLENKDVINQLEQGMRLPKPERCPPTL 590
Query: 816 YQLMLDCWQKERTHRPTFSSIV 837
Y LM CW RP+F+ +V
Sbjct: 591 YSLMTRCWSYSPRDRPSFTELV 612
>UniRef50_O76148 Cluster: Tyrosine-protein kinase receptor; n=1;
Anopheles sp.|Rep: Tyrosine-protein kinase receptor -
Anopheles sp
Length = 863
Score = 200 bits (488), Expect = 1e-49
Identities = 106/284 (37%), Positives = 166/284 (58%), Gaps = 15/284 (5%)
Query: 576 IDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEASI 635
+D + +++G G FG+V G +K E VAIKTLK G+ +++FL EA +
Sbjct: 446 LDQIFMASSSLLGSGAFGEVYEGVVK-GVDGEAETRVAIKTLKKGAKLHEKQEFLQEAQL 504
Query: 636 MGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRAND-----GKFRVLQLVGMLR 690
M F+H ++ L GV + + ++II E M+ G L ++L A + +L L+ M +
Sbjct: 505 MSNFKHKHITRLLGVCLEADALLIIMELMQGGDLLSYLPAQPLPGQAARLTMLDLISMCQ 564
Query: 691 GIATGMQYLSEMNYIHRDLAARNVLVNS----QLVCKIADFGLSREIESTADGAYTTRG- 745
+A+G +YL EM+++HRDLA RN LV+S V KI DFGL+R+I + Y G
Sbjct: 565 DVASGCRYLEEMHFVHRDLACRNCLVSSTDPRDRVVKIGDFGLARDIYK--NDYYRKEGE 622
Query: 746 GKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRL 805
G +PVRW +PE++ FTS SD+W+ G++ WE+M+ GE+PY +N +V+ + +G L
Sbjct: 623 GLLPVRWMSPESLVDGVFTSQSDIWAFGVLLWEIMTLGEQPYQAKNNVEVLNHVREGGHL 682
Query: 806 PAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLIRCPDT 849
P CP +Y+LM CW+ RPTF ++ L++ RC +T
Sbjct: 683 DRPKVCPNEMYELMKYCWKFSPEERPTFRYCLEVLER--RCQNT 724
>UniRef50_UPI0000F1FB23 Cluster: PREDICTED: similar to tyrosine
protein kinase BTK; n=1; Danio rerio|Rep: PREDICTED:
similar to tyrosine protein kinase BTK - Danio rerio
Length = 596
Score = 199 bits (486), Expect = 2e-49
Identities = 106/271 (39%), Positives = 155/271 (57%), Gaps = 12/271 (4%)
Query: 575 EIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEAS 634
EID +T +G G+FG V GK + DVAIK +K GS + DF+ EA
Sbjct: 331 EIDPRQLTFIRELGNGQFGVVKYGKWQ------GRHDVAIKMVKEGSM--SEDDFIEEAK 382
Query: 635 IMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFRVLQLVGMLRGIAT 694
+M + H N++ L GV TK PI I+TE++ NG L +L+ + L+ M + ++
Sbjct: 383 VMMKLCHGNLVQLYGVCTKQRPIYIVTEYLANGCLLNYLQEGLLNPTSIALLEMCKDVSE 442
Query: 695 GMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTR-GGKIPVRWT 753
GM+YL +IHRDLAARN LV+S K+ DFGLSR + D YT+ G K PVRW+
Sbjct: 443 GMKYLEANQFIHRDLAARNCLVDSNGTIKVTDFGLSRYV---LDDEYTSSVGSKFPVRWS 499
Query: 754 APEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCPE 813
PE + + KF+S SD+W+ G++ WE+ + G PY W+N ++++ I G+RL P E
Sbjct: 500 PPEVLLYCKFSSKSDIWAFGVLMWEIYTQGRMPYDRWNNTEIVEKISAGHRLYRPQMANE 559
Query: 814 AVYQLMLDCWQKERTHRPTFSSIVKTLDKLI 844
V+ +M CW + RPTF +V + L+
Sbjct: 560 NVFAIMNSCWHERPDERPTFQELVGVIKDLL 590
>UniRef50_P00529 Cluster: Tyrosine-protein kinase transforming
protein ros; n=3; root|Rep: Tyrosine-protein kinase
transforming protein ros - Avian sarcoma virus (strain
UR2)
Length = 402
Score = 198 bits (484), Expect = 4e-49
Identities = 113/297 (38%), Positives = 169/297 (56%), Gaps = 16/297 (5%)
Query: 565 PNQAVREFAREIDASCITIEAIIGGGEFGDVCRGK-LKLPASCGPEIDVAIKTLKPGSTE 623
P+QA E + + ++G G FG+V G L + A E VA+KTLK G+T+
Sbjct: 82 PSQAEIESLPAFPRDKLNLHKLLGSGAFGEVYEGTALDILADGSGESRVAVKTLKRGATD 141
Query: 624 RARRDFLAEASIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLR-ANDGKFR- 681
+ + +FL EA +M +F+HP+++ L GV P +I E ME G L ++LR A KF+
Sbjct: 142 QEKSEFLKEAHLMSKFDHPHILKLLGVCLLNEPQYLILELMEGGDLLSYLRGARKQKFQS 201
Query: 682 ----VLQLVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQL------VCKIADFGLSR 731
+ L+ + I G YL +M +IHRDLAARN LV+ + V KI DFGL+R
Sbjct: 202 PLLTLTDLLDICLDICKGCVYLEKMRFIHRDLAARNCLVSEKQYGSCSRVVKIGDFGLAR 261
Query: 732 EIESTADGAYTTRG-GKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNW 790
+I + Y RG G +PVRW APE++ FT+ SDVW+ G++ WE ++ G++PY
Sbjct: 262 DIYK--NDYYRKRGEGLLPVRWMAPESLIDGVFTNHSDVWAFGVLVWETLTLGQQPYPGL 319
Query: 791 SNQDVIKSIEKGYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLIRCP 847
SN +V+ + G RL +P +CP+ + LM CW ++ +RPTF I L ++ P
Sbjct: 320 SNIEVLHHVRSGGRLESPNNCPDDIRDLMTRCWAQDPHNRPTFFYIQHKLQEIRHSP 376
>UniRef50_Q01974 Cluster: Tyrosine-protein kinase transmembrane
receptor ROR2 precursor; n=36; Euteleostomi|Rep:
Tyrosine-protein kinase transmembrane receptor ROR2
precursor - Homo sapiens (Human)
Length = 943
Score = 198 bits (484), Expect = 4e-49
Identities = 113/286 (39%), Positives = 153/286 (53%), Gaps = 16/286 (5%)
Query: 566 NQAVREFAREIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERA 625
NQ + +EI S + +G FG V +G L PA VAIKTLK +
Sbjct: 458 NQHKQAKLKEISLSAVRFMEELGEDRFGKVYKGHLFGPAPGEQTQAVAIKTLKDKAEGPL 517
Query: 626 RRDFLAEASIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFL------------ 673
R +F EA + + +HPNV+ L GVVTK P+ +I + +G L FL
Sbjct: 518 REEFRHEAMLRARLQHPNVVCLLGVVTKDQPLSMIFSYCSHGDLHEFLVMRSPHSDVGST 577
Query: 674 ---RANDGKFRVLQLVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLS 730
R V ++ IA GM+YLS + +H+DLA RNVLV +L KI+D GL
Sbjct: 578 DDDRTVKSALEPPDFVHLVAQIAAGMEYLSSHHVVHKDLATRNVLVYDKLNVKISDLGLF 637
Query: 731 REIESTADGAYTTRGGKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNW 790
RE+ + AD +P+RW APEAI + KF+ SD+WS G+V WEV S+G +PY +
Sbjct: 638 REVYA-ADYYKLLGNSLLPIRWMAPEAIMYGKFSIDSDIWSYGVVLWEVFSYGLQPYCGY 696
Query: 791 SNQDVIKSIEKGYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSI 836
SNQDV++ I LP P DCP VY LM++CW + + RP F I
Sbjct: 697 SNQDVVEMIRNRQVLPCPDDCPAWVYALMIECWNEFPSRRPRFKDI 742
>UniRef50_UPI00015B5971 Cluster: PREDICTED: similar to leukocyte
receptor tyrosine protein kinase; n=1; Nasonia
vitripennis|Rep: PREDICTED: similar to leukocyte receptor
tyrosine protein kinase - Nasonia vitripennis
Length = 1472
Score = 198 bits (483), Expect = 6e-49
Identities = 107/299 (35%), Positives = 164/299 (54%), Gaps = 16/299 (5%)
Query: 575 EIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEAS 634
+I +T+ +G G FG+V +G K S E VA+KTL ST +A DF+ EA
Sbjct: 914 QIPRDSVTLVKPLGQGAFGEVFQGVYKYSRS--EEHPVAVKTLPSVSTSQAEADFMMEAL 971
Query: 635 IMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRANDGK------FRVLQLVGM 688
IM +FEHPN++ G+ +P I+ E + G L FLR + + L+
Sbjct: 972 IMSKFEHPNIVQFIGISFDKHPRYIVLELLAGGDLKNFLREERPRPDRPTTLTMQSLIMC 1031
Query: 689 LRGIATGMQYLSEMNYIHRDLAARNVLVNSQ---LVCKIADFGLSREIESTADGAYTTRG 745
+A G +Y+ E +IHRD+AARN L++ + V KIADFG++R+I + Y +G
Sbjct: 1032 AYDVAKGCKYMEEARFIHRDIAARNCLLSCKGPGRVVKIADFGMARDIYRSD---YYRKG 1088
Query: 746 GK--IPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGY 803
GK +P++W PE+ FT+ +DVW+ G++ WE+MSFG PY +N++V+ + G
Sbjct: 1089 GKAMLPIKWMPPESFLDGIFTTKTDVWAFGVLLWEIMSFGYMPYTGCANREVMSMVTSGG 1148
Query: 804 RLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLIRCPDTLRKIAQNRSADPL 862
RL P CP+ +Y +M CW RP+FSSIV+ + ++ PD + N P+
Sbjct: 1149 RLERPAGCPDPIYGIMTRCWHPHPEERPSFSSIVERIGYCLQDPDVINHPTPNYDLLPI 1207
>UniRef50_UPI0000E48523 Cluster: PREDICTED: similar to
protein-tyrosine kinase; n=3; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to protein-tyrosine
kinase - Strongylocentrotus purpuratus
Length = 837
Score = 198 bits (483), Expect = 6e-49
Identities = 108/261 (41%), Positives = 151/261 (57%), Gaps = 6/261 (2%)
Query: 576 IDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEASI 635
IDAS I IG GEFG V GK K + VA+KTL + +++FL EA +
Sbjct: 558 IDASLIERGNEIGQGEFGSVLEGKYKEKDRW---VKVALKTLHADHLQTGQKEFLREAKV 614
Query: 636 MGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFRVLQLVGMLRGIATG 695
M +HP ++ L GV P+M++ E + G+L FL+ ND L IA+G
Sbjct: 615 MCGLDHPCIVKLMGVCLG-PPMMLVQELVSQGALLDFLQ-NDS-ITASDLKLWATQIASG 671
Query: 696 MQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGGKIPVRWTAP 755
M YL ++HRDLAARN+L+ ++ KI+DFGLSR + D +T GG+ PV+W AP
Sbjct: 672 MMYLEGKKFVHRDLAARNILLENKGQAKISDFGLSRATGANNDYYRSTTGGRWPVKWYAP 731
Query: 756 EAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEAV 815
E+I + F+ +SDVW G+ WE+ S G +PY + +VIK IE G+RL P CP+ V
Sbjct: 732 ESIYYGTFSHSSDVWGFGVTLWEMNSRGAQPYGEKTGAEVIKQIENGHRLNRPEGCPQNV 791
Query: 816 YQLMLDCWQKERTHRPTFSSI 836
YQ+M CW + +RPTFS +
Sbjct: 792 YQIMNKCWSYKPCNRPTFSQL 812
>UniRef50_A7RHT9 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 295
Score = 198 bits (483), Expect = 6e-49
Identities = 100/280 (35%), Positives = 161/280 (57%), Gaps = 16/280 (5%)
Query: 581 ITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEASIMGQFE 640
+ ++G G FG V + + C + VA+K +K ++ ARRD +AE ++ +
Sbjct: 9 VKTSVVLGSGAFGVVMKADAQGIKGCVGSLPVAVKIVKENDSDTARRDLMAELDLLKLID 68
Query: 641 -HPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLR----ANDGKFRVLQLVGMLR----- 690
HPNVI L G T+ +P+M+I EF + G L ++LR D + + +V +
Sbjct: 69 PHPNVIGLLGCCTRGDPLMVIVEFCQYGDLQSYLRHCRGIEDKYYEQIYMVPEKKLTAKD 128
Query: 691 ----GI--ATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTR 744
GI A GM +L+ M +HRDLAARN+L++ + VCK++DFG +R+I T+
Sbjct: 129 LLSFGIQAARGMAHLASMKVVHRDLAARNILIDEKSVCKVSDFGFARDIYVEDHYTRKTQ 188
Query: 745 GGKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYR 804
GG+ P++W A E++ T+ SDVWS G++ WE+++ G PY ++Q+VI ++ GYR
Sbjct: 189 GGRFPIKWMAIESLLDGVSTTKSDVWSYGVLLWEIVTLGASPYPGMNSQEVINFLQDGYR 248
Query: 805 LPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLI 844
+ P C + +Y +MLDCWQ RPTF I + L+K++
Sbjct: 249 MDKPKHCLDELYAVMLDCWQLSAQRRPTFVEISRLLNKML 288
>UniRef50_UPI00015B5A01 Cluster: PREDICTED: similar to protein
kinase protein; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to protein kinase protein - Nasonia vitripennis
Length = 1337
Score = 198 bits (482), Expect = 8e-49
Identities = 108/284 (38%), Positives = 160/284 (56%), Gaps = 10/284 (3%)
Query: 581 ITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERAR--RDFLAEASIMGQ 638
+T+ +G G FG V RG+ P G + VA+K LK + + DF++E M
Sbjct: 139 VTLSVKLGDGSFGVVRRGEWTSPT--GRTLPVAVKVLKADALNQPNVVEDFVSEVQSMHM 196
Query: 639 FEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFRVLQLVGMLRGIATGMQY 698
+H N+I L GVV P+M++TE G+L +LR G VL L +ATGM Y
Sbjct: 197 LDHHNLIRLYGVVLS-QPMMMVTELAPLGALLDYLRKQCGHISVLTLCNYALQVATGMAY 255
Query: 699 LSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGGKIPVRWTAPEAI 758
L ++HRDLA RNVL++S KI DFGL R + D T K+P W APE++
Sbjct: 256 LEAKRFLHRDLACRNVLLSSVDKIKIGDFGLMRALPQQEDCYVMTEHKKVPFPWCAPESL 315
Query: 759 AFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEK-GYRLPAPMDCPEAVYQ 817
R+F+ ASDVW G+ WE+++FGE P+ + +++K I++ G RL P P A++Q
Sbjct: 316 KARQFSHASDVWMFGVTLWEMLTFGEEPWVGLNGSEILKKIDREGERLHEPEASPPAMFQ 375
Query: 818 LMLDCWQKERTHRPTFSSIVKTLDKLIRCPDTLRKIAQNRSADP 861
LML CW ++ RPTF+S+ ++L ++ P ++ A NR +P
Sbjct: 376 LMLHCWARDPAERPTFASLKESLTGMV--PSVMK--ALNRFDEP 415
>UniRef50_Q910A2 Cluster: Spleen protein tyrosine kinase; n=2; Danio
rerio|Rep: Spleen protein tyrosine kinase - Danio rerio
(Zebrafish) (Brachydanio rerio)
Length = 586
Score = 197 bits (481), Expect = 1e-48
Identities = 108/284 (38%), Positives = 165/284 (58%), Gaps = 10/284 (3%)
Query: 557 IDPHTYEDPNQAVREF-AREIDASCITIE-AIIGGGEFGDVCRGKLKLPASCGPEIDVAI 614
+D YE P E + +++ S +T+E +G G FG V RG ++ + + VA+
Sbjct: 296 MDTQVYESPYADPDELRSTKVNRSDLTLEDGELGSGNFGTVLRGVYQMKKT---QKVVAV 352
Query: 615 KTLKPGSTERARRD-FLAEASIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFL 673
K LK A +D L EA++M Q ++P ++ + G+ N +M++ E E G L FL
Sbjct: 353 KILKNDDDNAAVKDEMLREANVMQQLDNPYIVRMIGICEAEN-LMLVMELAELGPLHKFL 411
Query: 674 RANDGKFRVLQLVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREI 733
+ N V L ++ ++ GM+YL E N++HRDLAARNVL+ +Q KI+DFGLS+ +
Sbjct: 412 QKNK-HITVKNLTELVHQVSMGMKYLEEHNFVHRDLAARNVLLVTQHYAKISDFGLSKAL 470
Query: 734 ESTADGAYTTRG-GKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSN 792
+ + Y +G GK P++W APE + + KF+S SDVWS G++ WE S+G++PY
Sbjct: 471 -TEDENYYKAKGHGKWPLKWYAPECMNYLKFSSKSDVWSFGVLMWEAFSYGQKPYKGMKG 529
Query: 793 QDVIKSIEKGYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSI 836
+VI+ IE G R+ AP DCP +Y LM CW + RP FS +
Sbjct: 530 NEVIQMIENGQRMSAPPDCPPEMYDLMKKCWTYKPDERPGFSVV 573
>UniRef50_Q4H3B8 Cluster: Tyrosine-protein kinase receptor; n=1;
Ciona intestinalis|Rep: Tyrosine-protein kinase receptor
- Ciona intestinalis (Transparent sea squirt)
Length = 465
Score = 197 bits (481), Expect = 1e-48
Identities = 112/274 (40%), Positives = 149/274 (54%), Gaps = 9/274 (3%)
Query: 575 EIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEAS 634
EI + + IG G FG V G K P+ VA+KTL + R +FL EAS
Sbjct: 93 EIPEENVELMDEIGHGHFGKVYEGLAKQVVKGQPKTKVAVKTLHGNESISKRMEFLKEAS 152
Query: 635 IMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRAN--DGKFR------VLQLV 686
+M F +V+ L GVV+ M+I EFM G L T+LR+ D + R + Q +
Sbjct: 153 VMKAFNSHHVVRLLGVVSMSKRPMVIMEFMAKGDLKTYLRSTRPDAEIRKGDPPSLQQKL 212
Query: 687 GMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGG 746
M IA GM YLSE Y+HRDLAARN LV+ L KI DFGL+R++ T +RG
Sbjct: 213 QMCGEIADGMSYLSETKYVHRDLAARNCLVHEDLTVKIGDFGLTRDVYETDYYRIDSRG- 271
Query: 747 KIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLP 806
+PVRW APE++ F S SDVWS GIV WE+ + E+PY + V + + G +
Sbjct: 272 ILPVRWMAPESLKDGVFDSRSDVWSFGIVLWEIATLAEQPYQGQQHDQVTRFVIDGGYME 331
Query: 807 APMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTL 840
P +CP +Y +ML CW + RPTF IV +L
Sbjct: 332 QPKECPSKLYDMMLMCWHYSPSMRPTFLEIVASL 365
>UniRef50_P04629 Cluster: High affinity nerve growth factor receptor
precursor; n=28; Eumetazoa|Rep: High affinity nerve
growth factor receptor precursor - Homo sapiens (Human)
Length = 796
Score = 197 bits (480), Expect = 1e-48
Identities = 109/312 (34%), Positives = 169/312 (54%), Gaps = 20/312 (6%)
Query: 552 GSRTYIDPHTYEDPNQAVREFAREIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEID 611
G + + H E+P I I ++ +G G FG V + ++
Sbjct: 481 GKGSGLQGHIIENPQYFSDACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKML 540
Query: 612 VAIKTLKPGSTERARRDFLAEASIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDT 671
VA+K LK S E AR+DF EA ++ +H +++ GV T+ P++++ E+M +G L+
Sbjct: 541 VAVKALKEAS-ESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNR 599
Query: 672 FLRANDGKFRVL--------------QLVGMLRGIATGMQYLSEMNYIHRDLAARNVLVN 717
FLR++ ++L QL+ + +A GM YL+ ++++HRDLA RN LV
Sbjct: 600 FLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVG 659
Query: 718 SQLVCKIADFGLSREIESTADGAYTTRGGK--IPVRWTAPEAIAFRKFTSASDVWSMGIV 775
LV KI DFG+SR+I ST Y GG+ +P+RW PE+I +RKFT+ SDVWS G+V
Sbjct: 660 QGLVVKIGDFGMSRDIYSTD---YYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVV 716
Query: 776 CWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSS 835
WE+ ++G++P++ SN + I I +G L P CP VY +M CWQ+E R +
Sbjct: 717 LWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQRHSIKD 776
Query: 836 IVKTLDKLIRCP 847
+ L L + P
Sbjct: 777 VHARLQALAQAP 788
>UniRef50_Q4T351 Cluster: Chromosome undetermined SCAF10118, whole
genome shotgun sequence; n=2; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF10118,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 1168
Score = 196 bits (479), Expect = 2e-48
Identities = 104/269 (38%), Positives = 147/269 (54%), Gaps = 13/269 (4%)
Query: 45 NALSCKETFSLLYY--EFDVATREQPPWEPESYKLVGRIAAGE-GRFNTNSEVDINTEVK 101
N C+ETF+L YY E D AT P W Y +AA ++ S + + ++
Sbjct: 58 NQRHCRETFTLYYYPAERDEATPTHPAWMENPYVKAATVAADHLSGYDKRSNIKL---LR 114
Query: 102 SIAVTKKGVYFAFRDQGACISILAVKVYYITCPDVNINFARFPAT-PTG--REVTVIEQA 158
+ K G+Y AF+ QGAC+++LAV+V+Y CP + FA FP T P + + QA
Sbjct: 115 LEQLRKAGLYLAFQSQGACMALLAVRVFYRKCPPLRRAFASFPETVPHSLVEQSRCVLQA 174
Query: 159 NGTCVANAEVAPGEKAPV--YLCKGDGKWT-LPSGSCKCRAGFEPDHNNQICTECAPGKF 215
G CV NA P E +P LC DG+W P+ SC CR G+E + C C G F
Sbjct: 175 QGVCVENAVAPPTEHSPPPRMLCGEDGQWVGQPTSSCACRPGYEAQDTDVRCRACPSGHF 234
Query: 216 KSHTGDEHCIPCPDHSESTIYAAAECKCTPKYYRAKKDPKTIPCTQPPSAPDNLTVTFAD 275
K +G C PCP S + + +A C C+P+YYRA DP CT+PPSAP ++ V+ +
Sbjct: 235 KVGSGPGGCEPCPASSNTLVPGSAYCPCSPRYYRADADPAHAACTRPPSAPRSI-VSQLN 293
Query: 276 QFSISLTWQPPHNTGGRSDITYKISCANC 304
S++L W P + GGRSD+TY++ C+ C
Sbjct: 294 DTSVTLEWSEPLDRGGRSDLTYRLLCSVC 322
Score = 177 bits (430), Expect = 2e-42
Identities = 86/142 (60%), Positives = 108/142 (76%), Gaps = 5/142 (3%)
Query: 550 GTGSRTYIDPHTYEDPNQAVREFAREIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPE 609
G + YIDP TYEDPN+AVREFA+EI+AS + IE +IG GEFG+VCRG+L++P E
Sbjct: 655 GQTMKVYIDPFTYEDPNEAVREFAKEIEASFVKIEEVIGAGEFGEVCRGRLRVPGR--KE 712
Query: 610 IDVAIKTLKPGSTERARRDFLAEASIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSL 669
VAIKTLK G TE+ RRDFL+EASIMGQF+HPN+I L+GV+T P+MI+TEFMENG+L
Sbjct: 713 NYVAIKTLKGGYTEKQRRDFLSEASIMGQFQHPNIIHLEGVITTSCPVMILTEFMENGAL 772
Query: 670 DTFLRANDGKFRVLQLVGMLRG 691
D+FLR + VG +RG
Sbjct: 773 DSFLRVRRAE---AAAVGRVRG 791
Score = 39.9 bits (89), Expect = 0.32
Identities = 25/85 (29%), Positives = 41/85 (48%), Gaps = 4/85 (4%)
Query: 371 LRILNTESDRLTIAWNPPQVDLTDPDDTIESYEVKCFPKDSQDKNTNTTLRITKDPQVTI 430
LR L++ WN P V P I Y+++ KD ++ + +K V +
Sbjct: 487 LRRTAASETSLSLEWNVPFVQNQHP---ILDYQLRYSTKDGEEAGRWRYVS-SKSSSVVV 542
Query: 431 TGLRKDTEYGIRVRAKMKRGWGEFS 455
TGL+ +Y ++VRA+ G+G FS
Sbjct: 543 TGLQGALQYQVQVRARSGAGYGSFS 567
Score = 35.5 bits (78), Expect = 6.8
Identities = 14/23 (60%), Positives = 20/23 (86%)
Query: 910 LASLGVTLVGHQKKIMNSVQSMR 932
L +GVTL GHQKKI++S+Q++R
Sbjct: 1145 LLRVGVTLAGHQKKILSSIQTLR 1167
>UniRef50_Q9BKL8 Cluster: Tyrosine-protein kinase receptor; n=2;
Eumetazoa|Rep: Tyrosine-protein kinase receptor -
Aplysia californica (California sea hare)
Length = 1145
Score = 196 bits (479), Expect = 2e-48
Identities = 111/290 (38%), Positives = 157/290 (54%), Gaps = 20/290 (6%)
Query: 564 DPNQAVREFAREIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTE 623
+P A R ARE I +G G FG V +G+L VAIKTLK +
Sbjct: 556 NPKSASR--AREFPMPNIRFLQELGEGAFGKVYKGELVGLYGESSVTTVAIKTLKENALP 613
Query: 624 RARRDFLAEASIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRAND------ 677
+ + DF E +M HPN++ L GV K P+ ++ E+M G L +L ++
Sbjct: 614 KVQNDFRREVDLMSDMRHPNIVCLLGVCMKQEPMCMLFEYMAQGDLHEYLLSHSPHSDVT 673
Query: 678 --------GKFRVLQLVGMLR---GIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIAD 726
G +L+ ML +A GM+YL+ +++HRDLAARN+LV L KI+D
Sbjct: 674 AAEDDSGTGGGHILEYSEMLHVSTQVAAGMEYLASHHFVHRDLAARNILVADGLTVKISD 733
Query: 727 FGLSREIESTADGAYTTRGGKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERP 786
FGLSR++ S+ D +PVRW PEAI + KFT+ SDVW+ G+V WEV S+G +P
Sbjct: 734 FGLSRDVYSS-DYYRVQSKSLLPVRWMPPEAILYGKFTTDSDVWAFGVVLWEVFSYGLQP 792
Query: 787 YWNWSNQDVIKSIEKGYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSI 836
Y+ +SNQ+VI+ I L P +CP +Y LM++CW + RP F I
Sbjct: 793 YYGFSNQEVIEMIRSRQILGCPEECPARIYGLMVECWHEMPARRPPFREI 842
>UniRef50_Q5TUS8 Cluster: Tyrosine-protein kinase receptor; n=1;
Anopheles gambiae str. PEST|Rep: Tyrosine-protein kinase
receptor - Anopheles gambiae str. PEST
Length = 2075
Score = 196 bits (479), Expect = 2e-48
Identities = 104/279 (37%), Positives = 162/279 (58%), Gaps = 14/279 (5%)
Query: 576 IDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEASI 635
+D + +++G G FG+V G +K E VAIKTLK G+ +++FL EA +
Sbjct: 1800 LDQIFMASSSLLGSGAFGEVYEGVVK-GVDGEAETRVAIKTLKKGAKLHEKQEFLQEAQL 1858
Query: 636 MGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRANDG------KFRVLQLVGML 689
M F+H ++ L GV + + ++II E M+ G L ++LR + + +L L+ M
Sbjct: 1859 MSNFKHKHITRLLGVCLEADALLIIMELMQGGDLLSYLRRSRSLPGQAARLTMLDLISMC 1918
Query: 690 RGIATGMQYLSEMNYIHRDLAARNVLVNS----QLVCKIADFGLSREIESTADGAYTTRG 745
+ +A+G +YL EM+++HRDLA RN LV+S V KI DFGL+R+I + Y G
Sbjct: 1919 QDVASGCRYLEEMHFVHRDLACRNCLVSSTDPRDRVVKIGDFGLARDIYK--NDYYRKEG 1976
Query: 746 -GKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYR 804
G +PVRW +PE++ FTS SD+W+ G++ WE+M+ GE+PY +N +V+ + +G
Sbjct: 1977 EGLLPVRWMSPESLVDGVFTSQSDIWAFGVLLWEIMTLGEQPYQAKNNVEVLNHVREGGH 2036
Query: 805 LPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKL 843
L P CP +Y+LM CW+ RPTF ++ L L
Sbjct: 2037 LDRPKVCPNEMYELMKYCWKFSPEERPTFRYCLEVLRAL 2075
>UniRef50_Q25410 Cluster: Putative molluscan insulin-related
peptide(s) receptor precursor (EC 2.7.10.1) [Contains:
Putative molluscan insulin-related peptide(s) receptor
alpha chain; Putative molluscan insulin-related
peptide(s) receptor beta chain]; n=2; Coelomata|Rep:
Putative molluscan insulin-related peptide(s) receptor
precursor (EC 2.7.10.1) [Contains: Putative molluscan
insulin-related peptide(s) receptor alpha chain; Putative
molluscan insulin-related peptide(s) receptor beta chain]
- Lymnaea stagnalis (Great pond snail)
Length = 1607
Score = 196 bits (477), Expect = 3e-48
Identities = 109/277 (39%), Positives = 159/277 (57%), Gaps = 14/277 (5%)
Query: 575 EIDASCITIEAIIGGGEFGDVCRGKLK-LPASCGPEIDVAIKTLKPGSTERARRDFLAEA 633
E+D I + +G G FG V G K + EI VA+KT+ ++ RR+FL EA
Sbjct: 1031 EVDRDKIKLIKELGQGSFGMVYEGVAKGIRDDPNEEIPVAVKTVNDRASFSDRREFLKEA 1090
Query: 634 SIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRAN------DGKF--RVLQL 685
+ M +F +V+ L GVV+ P ++I E M G L +LR + G +L +
Sbjct: 1091 TTMKEFHCHHVVKLLGVVSTGQPALVIMELMALGDLKNYLRGHRPDEDHPGVMPPHLLDI 1150
Query: 686 VGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRG 745
+ M IA GM YL++ ++HRDLAARN +V+ + KI DFG++R+I T Y +G
Sbjct: 1151 LQMAGEIADGMAYLADKKFVHRDLAARNCMVSEERTVKIGDFGMTRDIYETD---YYRKG 1207
Query: 746 GK--IPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGY 803
GK +PVRW APE++ FTS SDVWS G+V WE+++ +PY SN++V+K I GY
Sbjct: 1208 GKGMLPVRWMAPESLKDGVFTSLSDVWSYGVVMWEMVTLAAQPYQGLSNEEVVKFISDGY 1267
Query: 804 RLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTL 840
+ P +CP + LM CW K+ RPTF +I++ L
Sbjct: 1268 IMELPENCPNEMAYLMQHCWAKKPNQRPTFKAIIEYL 1304
>UniRef50_UPI0000DB7F8D Cluster: PREDICTED: similar to Cad96Ca
CG10244-PA; n=3; Endopterygota|Rep: PREDICTED: similar
to Cad96Ca CG10244-PA - Apis mellifera
Length = 657
Score = 195 bits (476), Expect = 4e-48
Identities = 103/269 (38%), Positives = 155/269 (57%), Gaps = 13/269 (4%)
Query: 586 IIGGGEFGDVCRGK-LKLPASCGPEIDVAIKTLKPGSTERARRDFLAEASIMGQFE-HPN 643
I+G G FG V + + L + G I VA+KTLK +TER R D E +M + HPN
Sbjct: 364 ILGEGCFGQVWKCEALDIDGKSGAII-VAVKTLKENATERERLDLAQELRVMKNLDPHPN 422
Query: 644 VIFLQGVVTKCNPIMIITEFMENGSLDTFLRA-----NDGK--FRVLQLVGMLRGIATGM 696
V+ L G T+ P+ +I E++ G L +FLRA N G L G + IA GM
Sbjct: 423 VVRLLGCCTEREPMFVILEYVSGGKLQSFLRASREERNHGGPGLTSRDLTGFVYQIAKGM 482
Query: 697 QYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRG-GKIPVRWTAP 755
+YL+ IHRDLAARN+L++ CK+ADFG +R++ A+ Y + G++P+RW AP
Sbjct: 483 EYLASKGIIHRDLAARNILIDENRACKVADFGFARDV--AANQIYERKSEGRLPIRWMAP 540
Query: 756 EAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEAV 815
E++ F+ SD+WS G++ WE+++ G PY + +V++ I++GYRL P C +
Sbjct: 541 ESLYDNIFSVKSDIWSFGVLIWEIVTLGSTPYPGLAAAEVMRRIKEGYRLDRPEHCKREL 600
Query: 816 YQLMLDCWQKERTHRPTFSSIVKTLDKLI 844
Y +M CW K+ RP+F +V + L+
Sbjct: 601 YNIMYYCWDKDPACRPSFGELVSLTEGLL 629
>UniRef50_UPI0000DB6D22 Cluster: PREDICTED: similar to Alk CG8250-PA;
n=1; Apis mellifera|Rep: PREDICTED: similar to Alk
CG8250-PA - Apis mellifera
Length = 1436
Score = 195 bits (476), Expect = 4e-48
Identities = 122/382 (31%), Positives = 190/382 (49%), Gaps = 22/382 (5%)
Query: 575 EIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEAS 634
+I CIT+ +G G FG+V +G + + E VA+K + S + DF+ EA
Sbjct: 882 QIPRECITLIRPLGQGAFGEVFQGVYRYRRN--QEQPVAVKAIPSSSRPQTEADFMMEAL 939
Query: 635 IMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRANDGK------FRVLQLVGM 688
IM +F HPN++ GV + NP I+ E + G+L FLR + R+ L+
Sbjct: 940 IMSKFNHPNIVHFIGVSFERNPKYIVLELLAGGNLKNFLREERPRADRPTSLRMQDLIMC 999
Query: 689 LRGIATGMQYLSEMNYIHRDLAARNVLVNSQ---LVCKIADFGLSREIESTADGAYTTRG 745
+A G +Y+ E +IHRD+AARN L+ S+ + KIADFG++++I + Y +G
Sbjct: 1000 GFDVANGCKYMEEARFIHRDIAARNCLLTSKGPGRIVKIADFGMAKDIYRSD---YYRKG 1056
Query: 746 GK--IPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGY 803
GK +P++W PE+ FT+ +DVW+ G++ WE+MSFG PY +N++ + + G
Sbjct: 1057 GKAMLPIKWMPPESFLDGIFTTKTDVWAFGVLLWEIMSFGYIPYTGCTNREAMTMVTLGG 1116
Query: 804 RLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLIRCPDTLRKIAQNRSADPLA 863
RL P CP+ +Y LM CW RP+F++IV+ + ++ PD + N P+
Sbjct: 1117 RLEKPAGCPDPIYGLMTRCWHPRPEDRPSFATIVERIGYCLQDPDVINHPTPNFDILPIC 1176
Query: 864 GDTPDLIQFTSVEEWLECIKMSRYIEK--FRAAGISDMDAVVDLTVHQLASLGVTLVGHQ 921
D I E ECI + ++ + I D + +AS L
Sbjct: 1177 -DREVTIMRPDPE--TECINVQSELDACGYMQPRIIDSRSASQRMAQAIASNNPNLRNEN 1233
Query: 922 KKIMNSVQSMRAQIR-GSGPYG 942
MNS + Q R S PYG
Sbjct: 1234 PNRMNSNERNNTQARFQSIPYG 1255
>UniRef50_UPI0000D57520 Cluster: PREDICTED: similar to CG8250-PA; n=1;
Tribolium castaneum|Rep: PREDICTED: similar to CG8250-PA
- Tribolium castaneum
Length = 1284
Score = 195 bits (476), Expect = 4e-48
Identities = 105/288 (36%), Positives = 161/288 (55%), Gaps = 14/288 (4%)
Query: 574 REIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEA 633
++I + + +G G FG+V +G + E+ VA+KTL ST +A DFL EA
Sbjct: 813 KDIPREQLRLVKALGQGAFGEVYQGFYRQRPCDTVEMPVAVKTLPEMSTSQAEMDFLMEA 872
Query: 634 SIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRANDGK------FRVLQLVG 687
IM +F HPN++ GV +P I+ E + G L FLR + K + LV
Sbjct: 873 LIMSKFNHPNIVHFIGVCFDKHPRFIVLELLAGGDLKNFLRESRPKPERGSPLTMKDLVL 932
Query: 688 MLRGIATGMQYLSEMNYIHRDLAARNVLVNSQ---LVCKIADFGLSREIESTADGAYTTR 744
+ +A G +YL + +IHRD+AARN L+ ++ V KIADFG+SR++ + Y +
Sbjct: 933 IAVDVAKGCKYLEDNRFIHRDIAARNCLLTTKGPGRVVKIADFGMSRDVYRSD---YYRK 989
Query: 745 GGK--IPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKG 802
GGK +P++W PEA FTS +DVWS G++ WE+MS G PY +N++V++ + G
Sbjct: 990 GGKAMLPIKWMPPEAFLDGIFTSKTDVWSFGVLLWEIMSMGYMPYTGCANREVMQLVTSG 1049
Query: 803 YRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLIRCPDTL 850
RL P +CP +Y +M CW RPTF++I++ L ++ P +
Sbjct: 1050 GRLDPPANCPGPIYGIMTQCWHPTPEQRPTFATILERLGYCLQDPQVM 1097
>UniRef50_UPI00006A20DD Cluster: UPI00006A20DD related cluster; n=1;
Xenopus tropicalis|Rep: UPI00006A20DD UniRef100 entry -
Xenopus tropicalis
Length = 693
Score = 195 bits (476), Expect = 4e-48
Identities = 142/431 (32%), Positives = 204/431 (47%), Gaps = 36/431 (8%)
Query: 48 SCKETFSLLYYE--FDVATREQPPWEPESYKLVGRIAAGE-GRFNTN-SEVDINTEVKSI 103
SCKETF+L YY+ D+A PPW + V +AA GR N S VK++
Sbjct: 97 SCKETFNLYYYQANHDLANDHFPPWMENPWVRVDTVAADFLGRPNRRGSPGSTRLNVKTL 156
Query: 104 AV---TKKGVYFAFRDQGACISILAVKVYYITCPDVNINFARFPATPTGREVTVIEQANG 160
+ + G Y AF+DQGAC+++LAV+V+Y CP V + A FP T + E V+ A G
Sbjct: 157 RIGPLSGDGFYLAFQDQGACMALLAVRVFYRVCPAVVASLASFPKTVS--EGLVV-SAEG 213
Query: 161 TCVANAEVAPGEKAPVYLCKGDGKWTLPS-GSCKCRAGFEPDHNNQICTECAPGKFKSHT 219
+CV AE G K +Y C+ DG+W P+ G C C AG E CT G ++
Sbjct: 214 SCVEGAEGPLGRKPTMY-CREDGEWAKPAVGECACVAGREEKDGRTKCT--GKGAPQAPV 270
Query: 220 GDEHCIPCPDHSESTIYAAAECKCTPKYYRAKKDPKTIPCTQPPSAPDNLTVTFADQFSI 279
G E C+ CP S ST + +Y PPSAP ++ V + +
Sbjct: 271 GRERCMLCPRASASTAQGGSSSVIYIFFY----------SLAPPSAPRSI-VARVNGSGV 319
Query: 280 SLTWQPPHNTGGRSDITYKISCANC---GPTV-----EFRPGETGLNSTRVTISGLDPVT 331
L W P + GGR D+ Y++ C+ C GP + F P L R+ ++GL P
Sbjct: 320 DLEWSEPLDAGGRGDLYYEVQCSECAGGGPCIPCSRLNFTPRPQRLVDRRLRVAGLRPRV 379
Query: 332 EYKFQVYAENGVSELSPDPANHIEITAVTEAXXXXXXXKLRILNTESDRLTIAWNPPQVD 391
Y F+V A NGVSE S A E+ T+ ++ + LT+ W P +
Sbjct: 380 TYNFRVLALNGVSERSTSGALGEEVNVTTDRDVPLPVSGIQQMAASETTLTLRWATP-LH 438
Query: 392 LTDPDDTIESYEVKCFPKDSQDKNTNTTLRITKDPQVTITGLRKDTEYGIRVRAKMKRGW 451
I YEVK + KD Q+K ++ T + + + L T Y ++VRA+ + G+
Sbjct: 439 SAPTKGNILDYEVKYYAKD-QEKPLIKFMKTTSN-EALLAELLSGTVYVVQVRARTEAGY 496
Query: 452 GEFSGIVYART 462
G FSG +T
Sbjct: 497 GAFSGDTLVQT 507
Score = 182 bits (442), Expect = 5e-44
Identities = 87/132 (65%), Positives = 105/132 (79%), Gaps = 5/132 (3%)
Query: 550 GTGSRTYIDPHTYEDPNQAVREFAREIDASCITIEAIIGG---GEFGDVCRGKLKLPASC 606
G S+ YIDP TYEDPN+AVREFA+EID SC+ IE +IG GEFG+VCRG+LK+P
Sbjct: 564 GHNSKVYIDPFTYEDPNEAVREFAKEIDVSCVKIEEVIGAAPTGEFGEVCRGRLKVPGK- 622
Query: 607 GPEIDVAIKTLKPGSTERARRDFLAEASIMGQFEHPNVIFLQGVVTKCNPIMIITEFMEN 666
E VAIKTLK G TER RR+FL+EASIMGQF HPN+I L+GV+T P+MIITE+MEN
Sbjct: 623 -KENYVAIKTLKGGYTERQRREFLSEASIMGQFNHPNIIHLEGVITNNCPVMIITEYMEN 681
Query: 667 GSLDTFLRANDG 678
G+LD+FLR +DG
Sbjct: 682 GALDSFLRVSDG 693
>UniRef50_Q4SK07 Cluster: Tyrosine-protein kinase receptor; n=2;
Tetraodontidae|Rep: Tyrosine-protein kinase receptor -
Tetraodon nigroviridis (Green puffer)
Length = 1084
Score = 195 bits (476), Expect = 4e-48
Identities = 105/280 (37%), Positives = 159/280 (56%), Gaps = 16/280 (5%)
Query: 574 REIDASCITIEAIIGGGEFGDVCRG-KLKLPASCGPEIDVAIKTLKPGSTERARRDFLAE 632
+E+ I++ +G G FG+V G + +P P + VA+KTL +E+ DFL E
Sbjct: 492 KEVSRRNISLTRGLGHGAFGEVYEGLAVGIPGEPSP-LQVAVKTLPEVCSEQDELDFLME 550
Query: 633 ASIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRA------NDGKFRVLQLV 686
A I+ +F H N++ GV + P I+ E M G L TF+R + ++ L+
Sbjct: 551 ALIISKFSHQNIVRCVGVSLQAMPRFILLELMTGGDLKTFMRETRPRPEHPSSLTMVDLL 610
Query: 687 GMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQ---LVCKIADFGLSREIESTADGAYTT 743
+ R IA G QYL E +IHRD+AARN L+ + V KI DFG++R+I + Y
Sbjct: 611 NIARDIAKGCQYLEENQFIHRDIAARNCLLTCKGPGRVAKIGDFGMARDIYRAS---YYR 667
Query: 744 RGGK--IPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEK 801
+GG+ +PV+W PEA FTS +D WS G++ WE+ S G PY + SNQ+V++ +
Sbjct: 668 KGGRAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSRSNQEVLEFVTN 727
Query: 802 GYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLD 841
G R+ P +CP VY++M CWQ + RP FS+I++ +D
Sbjct: 728 GGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFSTILERID 767
>UniRef50_Q12866 Cluster: Proto-oncogene tyrosine-protein kinase MER
precursor; n=30; root|Rep: Proto-oncogene
tyrosine-protein kinase MER precursor - Homo sapiens
(Human)
Length = 999
Score = 195 bits (476), Expect = 4e-48
Identities = 115/287 (40%), Positives = 166/287 (57%), Gaps = 19/287 (6%)
Query: 576 IDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLK-PGSTERARRDFLAEAS 634
ID + + + I+G GEFG V G LK G + VA+KT+K S+ R +FL+EA+
Sbjct: 582 IDRNLLILGKILGEGEFGSVMEGNLK--QEDGTSLKVAVKTMKLDNSSHREIEEFLSEAA 639
Query: 635 IMGQFEHPNVIFLQGVVTKCNPI-----MIITEFMENGSLDTFL---RANDGKFRV-LQ- 684
M F HPNVI L GV + + M+I FM+ G L T+L R G + LQ
Sbjct: 640 CMKDFSHPNVIRLLGVCIEMSSQGIPKPMVILPFMKYGDLHTYLLYSRLETGPKHIPLQT 699
Query: 685 LVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTR 744
L+ + IA GM+YLS N++HRDLAARN ++ + +ADFGLS++I S G Y +
Sbjct: 700 LLKFMVDIALGMEYLSNRNFLHRDLAARNCMLRDDMTVCVADFGLSKKIYS---GDYYRQ 756
Query: 745 G--GKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKG 802
G K+PV+W A E++A R +TS SDVW+ G+ WE+ + G PY N ++ + G
Sbjct: 757 GRIAKMPVKWIAIESLADRVYTSKSDVWAFGVTMWEIRTRGMTPYPGVQNHEMYDYLLHG 816
Query: 803 YRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLIR-CPD 848
+RL P DC + +Y++M CW+ + RPTFS + L+KL+ PD
Sbjct: 817 HRLKQPEDCLDELYEIMYSCWRTDPLDRPTFSVLRLQLEKLLESLPD 863
>UniRef50_Q9PVZ4 Cluster: Insulin receptor precursor (EC 2.7.10.1)
(IR) (Xe-InsR) (XTK-1b) [Contains: Insulin receptor
subunit alpha; Insulin receptor subunit beta]; n=6;
Euteleostomi|Rep: Insulin receptor precursor (EC
2.7.10.1) (IR) (Xe-InsR) (XTK-1b) [Contains: Insulin
receptor subunit alpha; Insulin receptor subunit beta] -
Xenopus laevis (African clawed frog)
Length = 1362
Score = 195 bits (476), Expect = 4e-48
Identities = 116/314 (36%), Positives = 173/314 (55%), Gaps = 17/314 (5%)
Query: 575 EIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEAS 634
E+ I + +G G FG V G K PE+ VA+KT+ ++ R R +FL EAS
Sbjct: 1006 EVPRDKINLLRELGQGSFGMVYEGIAKDIIKGEPEVRVAVKTVNESASLRERIEFLNEAS 1065
Query: 635 IMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRA-------NDGKFR--VLQL 685
+M F +V+ L GVV+K P ++I E M +G L ++LR+ N G+ + ++
Sbjct: 1066 VMKAFNCHHVVRLLGVVSKGQPTLVIMELMAHGDLKSYLRSLRPDAENNPGRLAPTLKEI 1125
Query: 686 VGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRG 745
+ M I+ GM YL+ ++HRDLAARN +V KI DFG++R+I T Y +G
Sbjct: 1126 IQMAAEISDGMAYLNAKKFVHRDLAARNCMVADDYAVKIGDFGMTRDIYETD---YYRKG 1182
Query: 746 GK--IPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGY 803
GK +PVRW +PE++ FT+ SDVWS G+V WE+ S E+PY SN+ V+K + G
Sbjct: 1183 GKGLLPVRWMSPESLKDGVFTAFSDVWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGG 1242
Query: 804 RLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLIRCPDTLRKIAQNRSADPLA 863
L P +CP ++ LM CWQ RPTF I+ L +R + + ++ S +
Sbjct: 1243 SLDHPENCPPRLHSLMQMCWQYNPKMRPTFLEIIDMLKDDLR--PSFQDVSFYYSDENKP 1300
Query: 864 GDTPDL-IQFTSVE 876
+T DL I F ++E
Sbjct: 1301 PETDDLEIDFENME 1314
>UniRef50_Q9Y1X9 Cluster: Protein tyrosine kinase; n=1; Ephydatia
fluviatilis|Rep: Protein tyrosine kinase - Ephydatia
fluviatilis
Length = 573
Score = 194 bits (474), Expect = 7e-48
Identities = 101/273 (36%), Positives = 151/273 (55%), Gaps = 4/273 (1%)
Query: 569 VREFAREIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGST-ERARR 627
V+ R I+ S ++ + +G G FG V G + P + PE+ A+K LK +
Sbjct: 274 VKHGPRRIEDSELSTQGELGAGTFGTVRLGVYR-PKNGEPEVQCALKYLKQSEELPNQKA 332
Query: 628 DFLAEASIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFRVLQLVG 687
+ L EA M +H N++ L G+ +PI ++ E G L+ FLR F V++++
Sbjct: 333 EILREADAMAALDHCNIVRLFGICVG-DPICLVMELARQGPLNKFLRKRP-TFPVIKILN 390
Query: 688 MLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGGK 747
M ++ GM YL E+ ++HRDLAARNVLV KI+DFG+SR I + ++ G+
Sbjct: 391 MALQVSRGMAYLEEVRFVHRDLAARNVLVVDDDNVKISDFGMSRAIGAGSEYYKAETAGR 450
Query: 748 IPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPA 807
P++W APE I + KF S SDVWS G+ WE SFG +PY QD+++ +E RL +
Sbjct: 451 WPLKWYAPECIYYAKFDSKSDVWSYGVTVWEAFSFGAKPYAGLKGQDIMQMLEGNQRLDS 510
Query: 808 PMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTL 840
P CP+ +Y +ML CW RP+FS + L
Sbjct: 511 PEKCPQPIYDIMLRCWAWRPEDRPSFSELSSML 543
>UniRef50_UPI000065F6B2 Cluster: Receptor tyrosine-protein kinase
erbB-4 precursor (EC 2.7.10.1) (p180erbB4) (Tyrosine
kinase-type cell surface receptor HER4).; n=1; Takifugu
rubripes|Rep: Receptor tyrosine-protein kinase erbB-4
precursor (EC 2.7.10.1) (p180erbB4) (Tyrosine
kinase-type cell surface receptor HER4). - Takifugu
rubripes
Length = 1236
Score = 194 bits (473), Expect = 9e-48
Identities = 106/283 (37%), Positives = 153/283 (54%), Gaps = 6/283 (2%)
Query: 565 PNQAVREFAREIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTER 624
PNQA +E + + + +G G FG V +G + +P +I VA+K L + +
Sbjct: 657 PNQAQLRILKETELKRVKV---LGSGAFGTVYKG-IWVPEGEKVKIPVAVKILNEATGPK 712
Query: 625 ARRDFLAEASIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFRVLQ 684
A +F+ EA IM EHP+++ L GV I ++T+ M +G L ++ +
Sbjct: 713 ANVEFMDEALIMASMEHPHLVRLLGVCLSPT-IQLVTQLMPHGCLLDYVHEHKDNIGSQL 771
Query: 685 LVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTR 744
L+ IA GM YL E +HRDLAARNVLV S KI DFGL+R ++ + Y
Sbjct: 772 LLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHIKITDFGLARLLDVN-EKEYNAD 830
Query: 745 GGKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYR 804
GGK+ ++W A E I +RKFT SDVWS G+ WE+M+FG +PY S +D+ +EKG R
Sbjct: 831 GGKMAIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGKPYDGISTRDIPDLLEKGER 890
Query: 805 LPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLIRCP 847
LP P C VY +M+ CW + RP F + ++ R P
Sbjct: 891 LPQPPICTIDVYMVMVKCWMIDADSRPKFKELAAEFTRMARDP 933
>UniRef50_Q8JFV0 Cluster: Tyrosine-protein kinase receptor; n=5;
Euteleostomi|Rep: Tyrosine-protein kinase receptor -
Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 1161
Score = 194 bits (473), Expect = 9e-48
Identities = 106/288 (36%), Positives = 159/288 (55%), Gaps = 14/288 (4%)
Query: 574 REIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEA 633
+E+ IT+ +G G FG+V G++ + VAIKTL +E+ DFL EA
Sbjct: 559 KEVPRKNITLLRALGHGAFGEVYEGQVLGMNGENTAMQVAIKTLPEICSEQDEMDFLMEA 618
Query: 634 SIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRAN------DGKFRVLQLVG 687
IM +F H N++ GV + P I+ E M G + +FLR N +L+L+
Sbjct: 619 LIMSKFSHQNIVRCIGVSLQILPRFILLELMTGGDMKSFLRLNRPRTNHSSSLSMLELLH 678
Query: 688 MLRGIATGMQYLSEMNYIHRDLAARNVLVNS---QLVCKIADFGLSREIESTADGAYTTR 744
M R IA G +YL E ++IHRD+AARN L+ V KI DFG++R+I + Y +
Sbjct: 679 MARDIALGCRYLEENHFIHRDIAARNCLLTCPGPDRVAKIGDFGMARDIYRAS---YYRK 735
Query: 745 GGK--IPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKG 802
GG+ +PV+W PEA FT +D WS G++ WE+ S G PY +NQ+V++ + G
Sbjct: 736 GGRAMLPVKWMPPEAFLEGIFTCKTDTWSFGVLLWEIFSLGYMPYPCKTNQEVLEFVTGG 795
Query: 803 YRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLIRCPDTL 850
R+ P CP VY++M CWQ HRP F++I++ ++ + PD +
Sbjct: 796 GRMDPPKSCPGPVYRIMTQCWQHCPEHRPNFTTILERINYCTQDPDVI 843
>UniRef50_Q9Y1Y0 Cluster: Protein tyrosine kinase; n=1; Ephydatia
fluviatilis|Rep: Protein tyrosine kinase - Ephydatia
fluviatilis
Length = 472
Score = 194 bits (473), Expect = 9e-48
Identities = 108/289 (37%), Positives = 156/289 (53%), Gaps = 5/289 (1%)
Query: 553 SRTYIDPHTYEDPNQAVREFAREIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDV 612
S + +DP A E I S ++ IG G+FG+V R L E+ V
Sbjct: 179 SASLVDPSGSLTSLVADMENTFYISPSALSDLVPIGHGQFGEVFRATLH--KGTPGEVLV 236
Query: 613 AIKTLKPGSTERARRDFLAEASIMGQFEHPNVIFLQGVVTKC-NPIMIITEFMENGSLDT 671
A+KT K S+E+ R DF+ E ++M HPN++ GVV K + +I+ E++ G L +
Sbjct: 237 AVKTTKKDSSEKDRADFMKEMAVMSTLLHPNIVRFYGVVHKAVDSDLIVLEYLPFGDLKS 296
Query: 672 FLRANDGKFRVLQLVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSR 731
+L + QLV + +ATGM Y+SE +HRDLAARNVLV VCK+ADFGL R
Sbjct: 297 YLTKTTHSRK--QLVKYMIDVATGMHYISEKGLVHRDLAARNVLVGENEVCKVADFGLLR 354
Query: 732 EIESTADGAYTTRGGKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWS 791
E+ D ++ P++W PE+I KF+ ASDVWS G++ WE+ + + PY S
Sbjct: 355 ELPEDGDIYFSMHNIPCPIKWMPPESIDGGKFSVASDVWSFGVLMWEMFNPSKPPYQGMS 414
Query: 792 NQDVIKSIEKGYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTL 840
N + ++ KGYRLP P P + ++M CW + RP F I+ L
Sbjct: 415 NMECAVAVCKGYRLPLPRGIPSILAKVMESCWHQNPHKRPGFLIILSLL 463
>UniRef50_Q9BL77 Cluster: C-terminal src kinase protein 1; n=2;
Caenorhabditis|Rep: C-terminal src kinase protein 1 -
Caenorhabditis elegans
Length = 539
Score = 194 bits (473), Expect = 9e-48
Identities = 114/300 (38%), Positives = 161/300 (53%), Gaps = 16/300 (5%)
Query: 545 TPLFAGTGSRTYIDPHTY--EDPNQAVREFAREIDASCITIEAIIGGGEFGDVCRGKLKL 602
T F+ GS ++ T ED R I ++ I + IG GEFGDV G K
Sbjct: 245 TATFSSNGSSSFGSSSTVDLEDRTSVFRHAGLVISSNDIDVGDTIGHGEFGDVRLGTYK- 303
Query: 603 PASCGPEIDVAIKTLKPGSTERARRDFLAEASIMGQFEHPNVIFLQGVVTKCNPIMIITE 662
VA+K K L EA M HPN++ L GVV + +ITE
Sbjct: 304 ------NRKVALKVSKRHGNGMLD-SLLDEAKFMVGLSHPNLVTLVGVVLDDVNVYMITE 356
Query: 663 FMENGSLDTFLRANDGKFRV--LQLVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQL 720
+M NG+L LR+ G+ + QL+ I GM YL +HRDLAARNVL++ L
Sbjct: 357 YMANGNLIDLLRSR-GRHALERRQLMMFAMDICQGMCYLESKQIVHRDLAARNVLLDDDL 415
Query: 721 VCKIADFGLSREIESTADGAYTTRGGKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVM 780
V K++DFGL+++ S + + + GK P++WTAPEA+ +FT+ SDVWS GI+ WE+
Sbjct: 416 VAKVSDFGLAKKANSQS---HDSASGKFPIKWTAPEALRHSQFTTKSDVWSFGILLWEIF 472
Query: 781 SFGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTL 840
SFG PY QDV++ IEKGYR+ AP CP ++++M + W RP+F +++ L
Sbjct: 473 SFGRVPYPRIPIQDVVRYIEKGYRMEAPEGCPPEIFKVMNETWALSAQDRPSFGQVLQRL 532
>UniRef50_Q8INU0 Cluster: CG14396-PD, isoform D; n=10; Sophophora|Rep:
CG14396-PD, isoform D - Drosophila melanogaster (Fruit
fly)
Length = 1237
Score = 194 bits (473), Expect = 9e-48
Identities = 110/305 (36%), Positives = 164/305 (53%), Gaps = 17/305 (5%)
Query: 581 ITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEASIMGQFE 640
+ ++ ++G GEFG V +G A VA+K LK GS L+E ++ +
Sbjct: 773 LQLDTVLGEGEFGQVLKGFATEIAGLPGITTVAVKMLKKGSNSVEYMALLSEFQLLQEVS 832
Query: 641 HPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRAN-----------DG--KFRVLQLVG 687
HPNVI L G T ++I E+ GSL ++LR + DG V ++
Sbjct: 833 HPNVIKLLGACTSSEAPLLIIEYARYGSLRSYLRLSRKIECAGVDFADGVEPVNVKMVLT 892
Query: 688 MLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRG-G 746
I GM YLSE+ +HRDLAARNVL+ +CKI+DFGL+R++ D AY R
Sbjct: 893 FAWQICKGMAYLSELKLVHRDLAARNVLLADGKICKISDFGLTRDVYE--DDAYLKRSRD 950
Query: 747 KIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLP 806
++PV+W APE++A +TS SDVWS G++CWE+++ G PY + Q++ ++ GYR+
Sbjct: 951 RVPVKWMAPESLADHVYTSKSDVWSFGVLCWELITLGASPYPGIAPQNLWSLLKTGYRMD 1010
Query: 807 APMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLIRCPDTLRKIAQNRSADPL-AGD 865
P +C EAVY ++ CW E RP+F + +KL+ + N ++PL GD
Sbjct: 1011 RPENCSEAVYSIVRTCWADEPNGRPSFKFLASEFEKLLGNNAKYIDLETNAVSNPLYCGD 1070
Query: 866 TPDLI 870
LI
Sbjct: 1071 DSALI 1075
>UniRef50_P53356 Cluster: Tyrosine-protein kinase HTK16; n=1; Hydra
vulgaris|Rep: Tyrosine-protein kinase HTK16 - Hydra
attenuata (Hydra) (Hydra vulgaris)
Length = 757
Score = 194 bits (473), Expect = 9e-48
Identities = 99/253 (39%), Positives = 147/253 (58%), Gaps = 3/253 (1%)
Query: 587 IGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEASIMGQFEHPNVIF 646
+G GEFG V +G P G EI+VA+KTL + ++FL EA +M Q HP ++
Sbjct: 490 LGVGEFGSVIKGIWLSPG--GKEINVAMKTLHKDKMVQGEKEFLREALVMSQLNHPCIVS 547
Query: 647 LQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFRVLQLVGMLRGIATGMQYLSEMNYIH 706
L GV P++++ E +E G+L +L + + + L IA GM YL ++H
Sbjct: 548 LLGVCLG-PPMILVQELVEMGALLDYLMDYQPEIQEVDLKLWASQIAFGMMYLELKRFVH 606
Query: 707 RDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGGKIPVRWTAPEAIAFRKFTSA 766
RDLAARN+L+ ++ KI+DFGLSR + + +D +GG+ PVRW APE+I + F++
Sbjct: 607 RDLAARNILLANKKQVKISDFGLSRAVGTGSDYYQAKQGGRWPVRWYAPESINYGTFSTK 666
Query: 767 SDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEAVYQLMLDCWQKE 826
SDVWS GI WE+ +FG+ PY + +V+ +E RL P +CP Y +ML CW +
Sbjct: 667 SDVWSYGITLWEMFTFGDLPYGEMTGNEVVSFLEHCGRLEKPDECPIHTYSIMLSCWHID 726
Query: 827 RTHRPTFSSIVKT 839
RPTF+ + T
Sbjct: 727 PNKRPTFNELHST 739
>UniRef50_Q15303 Cluster: Receptor tyrosine-protein kinase erbB-4
precursor; n=58; Euteleostomi|Rep: Receptor
tyrosine-protein kinase erbB-4 precursor - Homo sapiens
(Human)
Length = 1308
Score = 194 bits (473), Expect = 9e-48
Identities = 106/283 (37%), Positives = 153/283 (54%), Gaps = 6/283 (2%)
Query: 565 PNQAVREFAREIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTER 624
PNQA +E + + + +G G FG V +G + +P +I VAIK L + +
Sbjct: 705 PNQAQLRILKETELKRVKV---LGSGAFGTVYKG-IWVPEGETVKIPVAIKILNETTGPK 760
Query: 625 ARRDFLAEASIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFRVLQ 684
A +F+ EA IM +HP+++ L GV I ++T+ M +G L ++ +
Sbjct: 761 ANVEFMDEALIMASMDHPHLVRLLGVCLSPT-IQLVTQLMPHGCLLEYVHEHKDNIGSQL 819
Query: 685 LVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTR 744
L+ IA GM YL E +HRDLAARNVLV S KI DFGL+R +E + Y
Sbjct: 820 LLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHVKITDFGLARLLEGD-EKEYNAD 878
Query: 745 GGKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYR 804
GGK+P++W A E I +RKFT SDVWS G+ WE+M+FG +PY +++ +EKG R
Sbjct: 879 GGKMPIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLEKGER 938
Query: 805 LPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLIRCP 847
LP P C VY +M+ CW + RP F + ++ R P
Sbjct: 939 LPQPPICTIDVYMVMVKCWMIDADSRPKFKELAAEFSRMARDP 981
>UniRef50_A6P4V4 Cluster: Tyrosine-protein kinase receptor; n=2; Homo
sapiens|Rep: Tyrosine-protein kinase receptor - Homo
sapiens (Human)
Length = 1310
Score = 194 bits (472), Expect = 1e-47
Identities = 107/289 (37%), Positives = 162/289 (56%), Gaps = 16/289 (5%)
Query: 574 REIDASCITIEAIIGGGEFGDVCRGKLK-LPASCGPEIDVAIKTLKPGSTERARRDFLAE 632
+E+ IT+ +G G FG+V G++ +P P + VA+KTL +E+ DFL E
Sbjct: 799 KEVPRKNITLIRGLGHGAFGEVYEGQVSGMPNDPSP-LQVAVKTLPEVCSEQDELDFLME 857
Query: 633 ASIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLR------ANDGKFRVLQLV 686
A I+ +F H N++ GV + P I+ E M G L +FLR + +L L+
Sbjct: 858 ALIISKFNHQNIVRCIGVSLQSLPRFILLELMAGGDLKSFLRETRPRPSQPSSLAMLDLL 917
Query: 687 GMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQ---LVCKIADFGLSREIESTADGAYTT 743
+ R IA G QYL E ++IHRD+AARN L+ V KI DFG++R+I + Y
Sbjct: 918 HVARDIACGCQYLEENHFIHRDIAARNCLLTCPGPGRVAKIGDFGMARDIYRAS---YYR 974
Query: 744 RGG--KIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEK 801
+GG +PV+W PEA FTS +D WS G++ WE+ S G PY + SNQ+V++ +
Sbjct: 975 KGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTS 1034
Query: 802 GYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLIRCPDTL 850
G R+ P +CP VY++M CWQ + RP F+ I++ ++ + PD +
Sbjct: 1035 GGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIILERIEYCTQDPDVI 1083
>UniRef50_P51813 Cluster: Cytoplasmic tyrosine-protein kinase BMX;
n=36; Euteleostomi|Rep: Cytoplasmic tyrosine-protein
kinase BMX - Homo sapiens (Human)
Length = 675
Score = 194 bits (472), Expect = 1e-47
Identities = 100/269 (37%), Positives = 154/269 (57%), Gaps = 10/269 (3%)
Query: 575 EIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEAS 634
E+ IT+ +G G+FG V GK K + DVA+K +K GS + +F EA
Sbjct: 411 ELKREEITLLKELGSGQFGVVQLGKWK------GQYDVAVKMIKEGSM--SEDEFFQEAQ 462
Query: 635 IMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFRVLQLVGMLRGIAT 694
M + HP ++ GV +K PI I+TE++ NG L +LR++ QL+ M +
Sbjct: 463 TMMKLSHPKLVKFYGVCSKEYPIYIVTEYISNGCLLNYLRSHGKGLEPSQLLEMCYDVCE 522
Query: 695 GMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGGKIPVRWTA 754
GM +L +IHRDLAARN LV+ L K++DFG++R + D ++ G K PV+W+A
Sbjct: 523 GMAFLESHQFIHRDLAARNCLVDRDLCVKVSDFGMTRYVLD--DQYVSSVGTKFPVKWSA 580
Query: 755 PEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEA 814
PE + K++S SDVW+ GI+ WEV S G++PY + N V+ + +G+RL P +
Sbjct: 581 PEVFHYFKYSSKSDVWAFGILMWEVFSLGKQPYDLYDNSQVVLKVSQGHRLYRPHLASDT 640
Query: 815 VYQLMLDCWQKERTHRPTFSSIVKTLDKL 843
+YQ+M CW + RPTF ++ +++ L
Sbjct: 641 IYQIMYSCWHELPEKRPTFQQLLSSIEPL 669
>UniRef50_Q9UM73 Cluster: ALK tyrosine kinase receptor precursor;
n=37; Euteleostomi|Rep: ALK tyrosine kinase receptor
precursor - Homo sapiens (Human)
Length = 1620
Score = 194 bits (472), Expect = 1e-47
Identities = 107/289 (37%), Positives = 162/289 (56%), Gaps = 16/289 (5%)
Query: 574 REIDASCITIEAIIGGGEFGDVCRGKLK-LPASCGPEIDVAIKTLKPGSTERARRDFLAE 632
+E+ IT+ +G G FG+V G++ +P P + VA+KTL +E+ DFL E
Sbjct: 1109 KEVPRKNITLIRGLGHGAFGEVYEGQVSGMPNDPSP-LQVAVKTLPEVCSEQDELDFLME 1167
Query: 633 ASIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLR------ANDGKFRVLQLV 686
A I+ +F H N++ GV + P I+ E M G L +FLR + +L L+
Sbjct: 1168 ALIISKFNHQNIVRCIGVSLQSLPRFILLELMAGGDLKSFLRETRPRPSQPSSLAMLDLL 1227
Query: 687 GMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQ---LVCKIADFGLSREIESTADGAYTT 743
+ R IA G QYL E ++IHRD+AARN L+ V KI DFG++R+I + Y
Sbjct: 1228 HVARDIACGCQYLEENHFIHRDIAARNCLLTCPGPGRVAKIGDFGMARDIYRAS---YYR 1284
Query: 744 RGG--KIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEK 801
+GG +PV+W PEA FTS +D WS G++ WE+ S G PY + SNQ+V++ +
Sbjct: 1285 KGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTS 1344
Query: 802 GYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLIRCPDTL 850
G R+ P +CP VY++M CWQ + RP F+ I++ ++ + PD +
Sbjct: 1345 GGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIILERIEYCTQDPDVI 1393
>UniRef50_UPI00015B51DA Cluster: PREDICTED: similar to
ENSANGP00000013218; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to ENSANGP00000013218 - Nasonia
vitripennis
Length = 972
Score = 193 bits (471), Expect = 2e-47
Identities = 105/287 (36%), Positives = 164/287 (57%), Gaps = 19/287 (6%)
Query: 575 EIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEAS 634
E S ++IE ++G GEFG V R K + A + VA+KTLK ++ D L+E
Sbjct: 495 EFPRSRLSIEQVLGEGEFGRVLRAKAQDIAGWQGQTTVAVKTLKEDASASELADLLSEYQ 554
Query: 635 IMGQFEHPNVIFLQGVVTKCN-PIMIITEFMENGSLDTFLRAN-----DGKFRV------ 682
++ + +HPNVI L G T PI +I EF E GSL +LR + +G+ +
Sbjct: 555 LLKEAQHPNVIRLLGACTTAGGPIYLIIEFAEFGSLRNYLRRSRHLESEGRPSIDPVVNY 614
Query: 683 ----LQLVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTAD 738
++ I+ GM YL+++ +HRDLAARNVL+ + VCKI+DFGL+R++ D
Sbjct: 615 TITPRDILSFAWQISKGMAYLADIKLVHRDLAARNVLLGAGKVCKISDFGLTRDVYE--D 672
Query: 739 GAYTTRG-GKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIK 797
AY R G++PV+W APE++A +TS SDVWS G++ WE+++ G PY ++
Sbjct: 673 DAYLKRSKGRVPVKWMAPESLADHVYTSKSDVWSFGVLLWELVTLGASPYPGVDVHNLYN 732
Query: 798 SIEKGYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLI 844
++ GYR+ P +C +Y+LM+ CW E RP+F + ++++
Sbjct: 733 LLKAGYRMEKPANCSHQLYKLMVSCWHDEPGMRPSFKELTCHWERML 779
>UniRef50_UPI0000F2052A Cluster: PREDICTED: similar to anaplastic
lymphoma kinase (Ki-1),; n=1; Danio rerio|Rep: PREDICTED:
similar to anaplastic lymphoma kinase (Ki-1), - Danio
rerio
Length = 1387
Score = 193 bits (471), Expect = 2e-47
Identities = 106/289 (36%), Positives = 163/289 (56%), Gaps = 16/289 (5%)
Query: 574 REIDASCITIEAIIGGGEFGDVCRG-KLKLPASCGPEIDVAIKTLKPGSTERARRDFLAE 632
+E+ I++ +G G FG+V G + +P P + VA+KTL +E+ DFL E
Sbjct: 788 KEVPRRNISLTRGLGHGAFGEVYEGLAVGIPGEPSP-MQVAVKTLPEVCSEQDELDFLME 846
Query: 633 ASIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRA------NDGKFRVLQLV 686
A I+ +F H N++ GV + P I+ E M G L +FLR + ++ L+
Sbjct: 847 ALIISKFSHQNIVRCIGVSLQALPHFILLELMAGGDLKSFLRETRPRLEHPSSLTMVDLL 906
Query: 687 GMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQ---LVCKIADFGLSREIESTADGAYTT 743
+ R IA G QYL E +IHRD+AARN L+ + V KI DFG++R+I + Y
Sbjct: 907 NIARDIARGCQYLEENQFIHRDIAARNCLLTCKGPGRVAKIGDFGMARDIYRAS---YYR 963
Query: 744 RGGK--IPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEK 801
+GG+ +PV+W PEA FTS +D WS G++ WE+ S G PY + SNQ+V++ +
Sbjct: 964 KGGRAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSRSNQEVLEFVTN 1023
Query: 802 GYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLIRCPDTL 850
G R+ P +CP VY++M WQ + RP FS+I++ +D ++ PD +
Sbjct: 1024 GGRMDPPKNCPGPVYRIMTQSWQHQPEDRPNFSTILERIDYCLQDPDVV 1072
>UniRef50_Q4SS18 Cluster: Chromosome undetermined SCAF14482, whole
genome shotgun sequence; n=2; Tetraodontidae|Rep:
Chromosome undetermined SCAF14482, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 621
Score = 193 bits (471), Expect = 2e-47
Identities = 114/327 (34%), Positives = 180/327 (55%), Gaps = 13/327 (3%)
Query: 514 KQPSDCNALNYRNGEVYTGPDRPAKTSSNATTPLFAGTGSRTYIDPHTYEDPNQAVREF- 572
+ PS+ +L +T P+ P + P +GT + +D YE P E
Sbjct: 291 RSPSNRMSLTQTWVARHTAPENPNPYETRL--PNTSGTDAMP-MDTEVYESPYADPDELR 347
Query: 573 AREIDASCITIE-AIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERA-RRDFL 630
+ +D S + +E +G G FG V +G K+ + E VA+K LK + R + L
Sbjct: 348 SSTVDRSQLFLEDGELGSGNFGTVMKGIYKMKKT---EKTVAVKILKNDEDNLSVREEML 404
Query: 631 AEASIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFRVLQLVGMLR 690
EA++M Q ++P ++ + G+ N +M++ E E G L FL+ + + + + ++
Sbjct: 405 REANVMQQLDNPYIVRMIGICEAEN-LMLVMELAELGPLHKFLQKHK-QISMKNITELVH 462
Query: 691 GIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRG-GKIP 749
++ GM+YL E N++HRDLAARNVL+ +Q KI+DFGLS+ + + Y +G GK P
Sbjct: 463 QVSVGMKYLEEHNFVHRDLAARNVLLVTQHYAKISDFGLSKAV-AEDKSYYKAKGHGKWP 521
Query: 750 VRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPM 809
V+W APE I + KF+S SDVWS G++ WE SFG++PY +V++ IE G R+ AP
Sbjct: 522 VKWYAPECINYFKFSSKSDVWSFGVLMWEAFSFGQKPYKGMKGNEVMQMIESGQRMEAPA 581
Query: 810 DCPEAVYQLMLDCWQKERTHRPTFSSI 836
+CP + LM CW + RP+FS +
Sbjct: 582 NCPSEMSDLMQACWTYKVEDRPSFSVV 608
>UniRef50_Q9Y1X8 Cluster: Protein tyrosine kinase; n=1; Ephydatia
fluviatilis|Rep: Protein tyrosine kinase - Ephydatia
fluviatilis
Length = 1193
Score = 193 bits (471), Expect = 2e-47
Identities = 102/292 (34%), Positives = 166/292 (56%), Gaps = 5/292 (1%)
Query: 586 IIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGS-TERARRDFLAEASIMGQFEHPNV 644
++G G FG V +G + P +VAIK LK + T +++ + L E ++M +H NV
Sbjct: 846 VLGSGAFGTVYKGHWR-PEGDPNCYEVAIKVLKEETATPQSQTELLREGAVMATMDHINV 904
Query: 645 IFLQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFRVLQLVGMLRGIATGMQYLSEMNY 704
+ L V +M+ITEF+ GSL ++L+ N ++ R IA GM YL E
Sbjct: 905 VRLY-CVCMGKQMMLITEFVRLGSLLSYLKNNQATLDAYSMLNFSRQIADGMAYLEEKRM 963
Query: 705 IHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGGKIPVRWTAPEAIAFRKFT 764
+HRDLAARNVLV++ + KI DFGL+R I+ + Y GG +P+RW APE+I ++T
Sbjct: 964 VHRDLAARNVLVHTPQLVKITDFGLTRIID-VGESHYKATGGMVPLRWMAPESIFLFEYT 1022
Query: 765 SASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEAVYQLMLDCWQ 824
SDVWS G+ WE+++FG PY + ++V + ++ G +L P C +Y L+ CW
Sbjct: 1023 HKSDVWSFGVTIWEILTFGRLPYKGKNGKEVSQLVKNGQQLERPATCDANLYHLLEQCWL 1082
Query: 825 KERTHRPTFSSIVKTLDKLIRCPDT-LRKIAQNRSADPLAGDTPDLIQFTSV 875
++T RP+FS++ +L+ ++ P ++ +A S + L L+++ +
Sbjct: 1083 HDQTKRPSFSALSNSLNVMLNDPTRYIQTVAMVASYEELKFLQDGLVKYEEI 1134
>UniRef50_Q7YT64 Cluster: Tyrosine-protein kinase receptor; n=1;
Crassostrea gigas|Rep: Tyrosine-protein kinase receptor
- Crassostrea gigas (Pacific oyster) (Crassostrea
angulata)
Length = 804
Score = 193 bits (471), Expect = 2e-47
Identities = 111/287 (38%), Positives = 160/287 (55%), Gaps = 24/287 (8%)
Query: 575 EIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEAS 634
E++ I + +G G FG V G + G EI VA+KT+ +T R R +FL+EAS
Sbjct: 329 EVERDKIQLIRELGQGSFGMVYEGVARDLYGKGGEIKVAVKTVNEHATYRERMEFLSEAS 388
Query: 635 IMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRAN-------DGKFR------ 681
M F +V+ L GVV+ P ++I E ME G L FLR + D F
Sbjct: 389 RMKAFSCNHVVRLLGVVSDGQPALLIMELMEKGDLKNFLRMHRPVEEDIDSTFAGIKEHI 448
Query: 682 ------VLQLVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIES 735
+ +++ M IA GM YL++ ++HRDLAARN +V L KIADFG++R+I
Sbjct: 449 SRTPPTIKRIIQMAGEIADGMAYLADKKFVHRDLAARNCMVAEDLTVKIADFGMTRDIYE 508
Query: 736 TADGAYTTRGGK--IPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQ 793
T Y +GGK +PVRW APE++ FTS SDVWS G+V WE+ + +PY SN+
Sbjct: 509 TD---YYRKGGKALLPVRWMAPESLKDGIFTSLSDVWSYGVVLWEMATLAAQPYQGLSNE 565
Query: 794 DVIKSIEKGYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTL 840
+V++ + G + P DCP+ +++LM CW+ RPTF I++ L
Sbjct: 566 EVLRYVLNGRVMEKPEDCPDRLFELMQKCWRYRPKQRPTFKEILEEL 612
>UniRef50_Q2LC18 Cluster: Tyrosine-protein kinase receptor; n=2;
Strongylocentrotus purpuratus|Rep: Tyrosine-protein
kinase receptor - Strongylocentrotus purpuratus (Purple
sea urchin)
Length = 1072
Score = 193 bits (471), Expect = 2e-47
Identities = 107/263 (40%), Positives = 154/263 (58%), Gaps = 10/263 (3%)
Query: 587 IGGGEFGDVCRGKLKLPASCGPEID-VAIKTLKPGSTERARRDFLAEASIMGQFEHPNVI 645
+G G FG V G K EI VAIK+++ ++ R R +FL EAS+M + NV+
Sbjct: 705 LGKGSFGMVYEGLAKGILPEEEEISRVAIKSVQANASMRDRIEFLNEASVMKLIDAHNVV 764
Query: 646 FLQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFR--------VLQLVGMLRGIATGMQ 697
L GVV+K P +I EFM G L +LRA + + + QL+ M IA GM
Sbjct: 765 RLLGVVSKGQPTYVIMEFMAQGDLKNWLRARRPENQQDLPSVPTLEQLLNMAAEIADGMS 824
Query: 698 YLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGGKIPVRWTAPEA 757
+L+ Y+HRDL+ARN LV+ + CK+ADFGL+R+I + D RGG +P+RW APE+
Sbjct: 825 FLAARKYVHRDLSARNCLVSGEGTCKVADFGLARDIYQS-DYYRKERGGMLPIRWMAPES 883
Query: 758 IAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEAVYQ 817
+ F ++SDVWS GI+ WE+ + GE PY SN++ + I+ G L P +CPE + +
Sbjct: 884 VKDGVFQASSDVWSFGILLWEMATLGELPYQGLSNEEAGEYIKGGNVLRPPENCPEKMQE 943
Query: 818 LMLDCWQKERTHRPTFSSIVKTL 840
+M+ CWQ + RP F I+ L
Sbjct: 944 IMMACWQYQEKLRPLFGEIILNL 966
>UniRef50_O77132 Cluster: Non-receptor protein-tyrosine kinase CSK;
n=1; Hydra vulgaris|Rep: Non-receptor protein-tyrosine
kinase CSK - Hydra attenuata (Hydra) (Hydra vulgaris)
Length = 467
Score = 193 bits (471), Expect = 2e-47
Identities = 101/257 (39%), Positives = 148/257 (57%), Gaps = 16/257 (6%)
Query: 581 ITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEASIMGQFE 640
+ + +IG GEFG+V +G + VAIK L+ S + + LAEAS+M +
Sbjct: 213 VEFKELIGKGEFGNVYKG-------VWAKKTVAIKKLRDDS--KTAQSLLAEASVMTTLQ 263
Query: 641 HPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFRVLQ-LVGMLRGIATGMQYL 699
H N++ L + + + I+I+TE+ E G L +LR L+ G + GM+YL
Sbjct: 264 HKNLVVLVAISFQGDSILILTEYCEKGVLVEYLRTRGRAVITLEEQKGFAIDVCNGMRYL 323
Query: 700 SEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGGKIPVRWTAPEAIA 759
E N IHRDLAARNVL++ +L K++DFGL++++E GK PV+WTAPEAI
Sbjct: 324 EEKNIIHRDLAARNVLLSDELCAKVSDFGLAKDVEQEL------ASGKFPVKWTAPEAIE 377
Query: 760 FRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEAVYQLM 819
+ F++ SDVWS GI+ WE+ SFG PY +++ I+ YR+ P CP VYQLM
Sbjct: 378 LKIFSTKSDVWSFGILLWEIFSFGRNPYPREPLDELLTKIKSNYRMECPEKCPPFVYQLM 437
Query: 820 LDCWQKERTHRPTFSSI 836
L CW + + RP+F +
Sbjct: 438 LKCWDADPSRRPSFKQL 454
>UniRef50_P06213 Cluster: Insulin receptor precursor (EC 2.7.10.1)
(IR) (CD220 antigen) [Contains: Insulin receptor subunit
alpha; Insulin receptor subunit beta]; n=100;
Euteleostomi|Rep: Insulin receptor precursor (EC
2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin
receptor subunit alpha; Insulin receptor subunit beta] -
Homo sapiens (Human)
Length = 1382
Score = 193 bits (471), Expect = 2e-47
Identities = 110/277 (39%), Positives = 156/277 (56%), Gaps = 14/277 (5%)
Query: 575 EIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEAS 634
E+ IT+ +G G FG V G + E VA+KT+ ++ R R +FL EAS
Sbjct: 1017 EVSREKITLLRELGQGSFGMVYEGNARDIIKGEAETRVAVKTVNESASLRERIEFLNEAS 1076
Query: 635 IMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRA-------NDGKF--RVLQL 685
+M F +V+ L GVV+K P +++ E M +G L ++LR+ N G+ + ++
Sbjct: 1077 VMKGFTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSYLRSLRPEAENNPGRPPPTLQEM 1136
Query: 686 VGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRG 745
+ M IA GM YL+ ++HRDLAARN +V KI DFG++R+I T Y +G
Sbjct: 1137 IQMAAEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETD---YYRKG 1193
Query: 746 GK--IPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGY 803
GK +PVRW APE++ FT++SD+WS G+V WE+ S E+PY SN+ V+K + G
Sbjct: 1194 GKGLLPVRWMAPESLKDGVFTTSSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGG 1253
Query: 804 RLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTL 840
L P +CPE V LM CWQ RPTF IV L
Sbjct: 1254 YLDQPDNCPERVTDLMRMCWQFNPKMRPTFLEIVNLL 1290
>UniRef50_UPI0000DB6DD4 Cluster: PREDICTED: similar to Insulin-like
growth factor 1 receptor precursor (Insulin-like growth
factor I receptor) (IGF-I receptor); n=1; Apis
mellifera|Rep: PREDICTED: similar to Insulin-like growth
factor 1 receptor precursor (Insulin-like growth factor
I receptor) (IGF-I receptor) - Apis mellifera
Length = 855
Score = 193 bits (470), Expect = 2e-47
Identities = 107/279 (38%), Positives = 161/279 (57%), Gaps = 12/279 (4%)
Query: 575 EIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEAS 634
E+ I + +G G FG V G K E+ A+KT+ +T+R R +FL EAS
Sbjct: 324 EVPREKIEMLRSLGTGTFGMVYEGIAKDIVKGKSEVRCAVKTVNKDATDRERIEFLNEAS 383
Query: 635 IMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRAN-------DGKFRVLQLVG 687
+M F+ +V+ L GVVT+ P ++I E M NG L +LR++ + ++ +++
Sbjct: 384 VMKGFDAHHVVKLLGVVTRGQPTLVIMELMVNGDLKRYLRSHRPCENMSNAPPKLDRILQ 443
Query: 688 MLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGGK 747
M IA GM YLS ++HRDLAARN +V L K+ DFG++R+I + Y +G K
Sbjct: 444 MAIEIADGMAYLSTKKFVHRDLAARNCMVAEDLTVKVGDFGMTRDIY---ERDYYRKGSK 500
Query: 748 --IPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRL 805
+PVRW APE++ F+S SDVWS G+V WE+++F +PY SN+ V++ + +G +
Sbjct: 501 GLLPVRWMAPESLKDGVFSSYSDVWSYGVVLWEMVTFASQPYQGLSNEQVLRYVIEGGVM 560
Query: 806 PAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLI 844
P +CPE +Y+LM W+ + T RPTF I L K I
Sbjct: 561 ERPENCPELLYELMKRTWRHKATRRPTFMDIASMLLKHI 599
>UniRef50_P04626 Cluster: Receptor tyrosine-protein kinase erbB-2
precursor; n=36; Euteleostomi|Rep: Receptor
tyrosine-protein kinase erbB-2 precursor - Homo sapiens
(Human)
Length = 1255
Score = 193 bits (470), Expect = 2e-47
Identities = 107/297 (36%), Positives = 159/297 (53%), Gaps = 7/297 (2%)
Query: 565 PNQAVREFAREIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTER 624
PNQA +E + + + +G G FG V +G + +P +I VAIK L+ ++ +
Sbjct: 707 PNQAQMRILKETELRKVKV---LGSGAFGTVYKG-IWIPDGENVKIPVAIKVLRENTSPK 762
Query: 625 ARRDFLAEASIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFRVLQ 684
A ++ L EA +M P V L G+ + + ++T+ M G L +R N G+
Sbjct: 763 ANKEILDEAYVMAGVGSPYVSRLLGICLT-STVQLVTQLMPYGCLLDHVRENRGRLGSQD 821
Query: 685 LVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTR 744
L+ IA GM YL ++ +HRDLAARNVLV S KI DFGL+R ++ + Y
Sbjct: 822 LLNWCMQIAKGMSYLEDVRLVHRDLAARNVLVKSPNHVKITDFGLARLLDID-ETEYHAD 880
Query: 745 GGKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYR 804
GGK+P++W A E+I R+FT SDVWS G+ WE+M+FG +PY +++ +EKG R
Sbjct: 881 GGKVPIKWMALESILRRRFTHQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGER 940
Query: 805 LPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLIRCPDTLRKIAQNRSADP 861
LP P C VY +M+ CW + RP F +V ++ R P + QN P
Sbjct: 941 LPQPPICTIDVYMIMVKCWMIDSECRPRFRELVSEFSRMARDPQRF-VVIQNEDLGP 996
>UniRef50_UPI0000DB6C99 Cluster: PREDICTED: similar to proto-oncogene
c-ros-1 protein precursor; n=1; Apis mellifera|Rep:
PREDICTED: similar to proto-oncogene c-ros-1 protein
precursor - Apis mellifera
Length = 2105
Score = 192 bits (469), Expect = 3e-47
Identities = 107/275 (38%), Positives = 162/275 (58%), Gaps = 16/275 (5%)
Query: 581 ITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEASIMGQFE 640
IT+ +G G FG+V +G K G VAIKTL+ G++ + + +FL EA +M F
Sbjct: 1807 ITLAKFLGSGAFGEVFQGNAKDLERPGIT-PVAIKTLRKGASAQEKTEFLQEARLMSHFR 1865
Query: 641 HPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRANDG-------KFRVLQLVGMLRGIA 693
H +V+ L GV +P +++ E ME G L ++LRA+ R+ L+ M +A
Sbjct: 1866 HKHVLRLLGVCLDTDPPLLVLELMEAGDLLSYLRASRSLQPSDSHALRLQDLLAMCEDVA 1925
Query: 694 TGMQYLSEMNYIHRDLAARNVLVNSQ----LVCKIADFGLSREIESTADGAYTTRG-GKI 748
G +YL E++++HRDLA RN LV+++ V KI DFGL+R+I + Y G G +
Sbjct: 1926 RGCRYLEELHFVHRDLACRNCLVSAKDRENRVVKIGDFGLARDIYK--NDYYRKEGEGLL 1983
Query: 749 PVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAP 808
PVRW APE++ FTS SDVW+ G++ WE+ S G++PY +N +V+ + G RL P
Sbjct: 1984 PVRWMAPESLVDGVFTSQSDVWAFGVLMWEITSLGQQPYPARTNIEVLHHVRAGGRLSKP 2043
Query: 809 MDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKL 843
++CP A++QLML CW T RP+F ++ + L
Sbjct: 2044 LNCPLALHQLMLRCWSDVDT-RPSFKVCLENIVSL 2077
>UniRef50_Q60I21 Cluster: TEC family protein tyrosine kinase; n=1;
Eptatretus burgeri|Rep: TEC family protein tyrosine
kinase - Eptatretus burgeri (Inshore hagfish)
Length = 636
Score = 192 bits (469), Expect = 3e-47
Identities = 107/284 (37%), Positives = 156/284 (54%), Gaps = 13/284 (4%)
Query: 563 EDPNQAVREFAR-EIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGS 621
E P+ A + + E+DA +T +G G G V G + G +AI+ L G
Sbjct: 359 ELPSTAGLSYGKWELDALELTSLRELGRGALGVVQLGMWR-----GVR-HIAIRMLHEGV 412
Query: 622 TERARRDFLAEASIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFR 681
A DF E +M Q HPN++ L GVVT+ P+ I+ E++ G L TFL+A GK
Sbjct: 413 L--AEDDFFHEVKLMMQLSHPNLVQLYGVVTRYRPLRIVMEYLALGCLRTFLQARPGKLG 470
Query: 682 VLQLVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAY 741
L+ + M YL +++HRDLAAR+ LV K++DFG++R + D Y
Sbjct: 471 SAWLLEACSDVCKAMVYLESNSFLHRDLAARHCLVGEDFSIKVSDFGMARYV---LDDQY 527
Query: 742 T-TRGGKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIE 800
T ++G + PV+W+ PE +F+S SDVWS G+V WEV S G PY WSN +V++S+
Sbjct: 528 TCSQGARFPVKWSPPEVFDRGRFSSKSDVWSFGVVMWEVFSEGTLPYDGWSNGEVVESVH 587
Query: 801 KGYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLI 844
GY+LP P P VY +M DCWQ + RP F +++ + L+
Sbjct: 588 AGYQLPQPTLAPTPVYTIMCDCWQPDPEKRPYFMKLLELITDLM 631
>UniRef50_O73798 Cluster: Insulin-like growth factor 1 receptor
precursor (EC 2.7.10.1) (xIGF- 1R) (xIGFR) [Contains:
Insulin-like growth factor 1 receptor alpha chain;
Insulin-like growth factor 1 receptor beta chain]; n=25;
Euteleostomi|Rep: Insulin-like growth factor 1 receptor
precursor (EC 2.7.10.1) (xIGF- 1R) (xIGFR) [Contains:
Insulin-like growth factor 1 receptor alpha chain;
Insulin-like growth factor 1 receptor beta chain] -
Xenopus laevis (African clawed frog)
Length = 1358
Score = 192 bits (469), Expect = 3e-47
Identities = 105/277 (37%), Positives = 159/277 (57%), Gaps = 14/277 (5%)
Query: 575 EIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEAS 634
E+ IT+ +G G FG V G K E VAIKT+ ++ R R +FL EAS
Sbjct: 989 EVPREKITMNRELGQGSFGMVYEGIAKGVVKDEAETKVAIKTVNEAASMRERIEFLNEAS 1048
Query: 635 IMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRA-------NDGKFR--VLQL 685
+M +F +V+ L GVV++ P ++I E M G L ++LR+ N G+ + ++
Sbjct: 1049 VMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSLRPDTESNSGQPTPSLKKM 1108
Query: 686 VGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRG 745
+ M IA GM YL+ ++HRDLAARN +V KI DFG++R+I T Y +G
Sbjct: 1109 IQMAGEIADGMSYLNANKFVHRDLAARNCMVTEDFTVKIGDFGMTRDIYETD---YYRKG 1165
Query: 746 GK--IPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGY 803
GK +PVRW +PE++ FT+ SDVWS G+V WE+ + E+PY SN+ V++ + +G
Sbjct: 1166 GKGLLPVRWMSPESLKDGVFTTNSDVWSFGVVLWEIATLAEQPYQGMSNEQVLRFVMEGG 1225
Query: 804 RLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTL 840
L P +CP+ +++LM CWQ RP+F I+ ++
Sbjct: 1226 LLEKPDNCPDMLFELMRMCWQFNPKMRPSFLEIISSI 1262
>UniRef50_UPI0000E4736E Cluster: PREDICTED: similar to src-family
protein tyrosine kinase; n=2; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to src-family protein
tyrosine kinase - Strongylocentrotus purpuratus
Length = 387
Score = 192 bits (468), Expect = 4e-47
Identities = 103/248 (41%), Positives = 146/248 (58%), Gaps = 11/248 (4%)
Query: 587 IGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEASIMGQFEHPNVIF 646
+G G+FG+V +G VA+KTLK + A FLAEA++M + H ++
Sbjct: 132 LGEGKFGEVWQGVWN------GNTPVAVKTLKERTMSPAA--FLAEANVMKKLRHEGIVQ 183
Query: 647 LQGVVTKCNPIMIITEFMENGSLDTFLRANDGK-FRVLQLVGMLRGIATGMQYLSEMNYI 705
L V + PI I+TE M NG L T+L+++ K ++ L+ M IA+GM YL N +
Sbjct: 184 LYAVCSDKEPIYIVTELMSNGDLRTYLKSDKCKNTKMTTLIDMGAHIASGMDYLGSKNVV 243
Query: 706 HRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGGKIPVRWTAPEAIAFRKFTS 765
HRDLAARNVLV V KIADFG ++ +E D G K+P++WTAPEA+ +FT
Sbjct: 244 HRDLAARNVLVGKGNVVKIADFGRAQLMEK--DVYVGEEGAKLPLKWTAPEAVLHGRFTI 301
Query: 766 ASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEAVYQLMLDCWQK 825
SDVWS GI+ E+++FG PY ++V K + GYR+P C +++Y +ML CW K
Sbjct: 302 KSDVWSFGILMTEMVTFGGYPYKKMRTREVTKKVANGYRMPKMDHCTDSLYMIMLKCWHK 361
Query: 826 ERTHRPTF 833
+ RPTF
Sbjct: 362 DPQQRPTF 369
>UniRef50_UPI0000D5603D Cluster: PREDICTED: similar to Insulin
receptor precursor (IR); n=1; Tribolium castaneum|Rep:
PREDICTED: similar to Insulin receptor precursor (IR) -
Tribolium castaneum
Length = 1293
Score = 192 bits (468), Expect = 4e-47
Identities = 107/288 (37%), Positives = 163/288 (56%), Gaps = 14/288 (4%)
Query: 564 DPNQAVREFAREIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTE 623
+P+Q EI + + I +G G FG V G+ P + VA+KTLK GS+
Sbjct: 884 NPSQITDLDKWEIPRNSVVINRKLGEGAFGTVYGGEANFPDKGW--VAVAVKTLKVGSST 941
Query: 624 RARRDFLAEASIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRA-----ND- 677
+ DFL+EA +M +F+H N+I L GV TK PI I EFM G L TFL A ND
Sbjct: 942 EEKLDFLSEAEVMKRFDHKNIIKLLGVCTKEEPIYTIMEFMLYGDLKTFLLARRHLVNDK 1001
Query: 678 -----GKFRVLQLVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSRE 732
+ +L M +A G+ YL+++ Y+HRD+A+RN L+N+Q + K+ADFG++R
Sbjct: 1002 TIEESDEISSKKLTMMALDVARGLSYLAQLKYVHRDVASRNCLINAQRIVKLADFGMTRP 1061
Query: 733 IESTADGAYTTRGGKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSN 792
+ D TR G +PVRW +PE++A FT +SDVWS G++ +E+++FG PY +N
Sbjct: 1062 MFEN-DYYKFTRKGMLPVRWMSPESLALGVFTPSSDVWSYGVLLYEIITFGSFPYQGMTN 1120
Query: 793 QDVIKSIEKGYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTL 840
+V++ ++ G+ + P + L+ CW ++ R S IV+ L
Sbjct: 1121 GEVLEYVKNGHTVTIPQGVKTQLRGLLKSCWHQDPKMRTRASEIVEFL 1168
>UniRef50_Q08BY6 Cluster: Zgc:153964; n=3; Danio rerio|Rep:
Zgc:153964 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 511
Score = 192 bits (468), Expect = 4e-47
Identities = 111/261 (42%), Positives = 148/261 (56%), Gaps = 12/261 (4%)
Query: 583 IEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEASIMGQFEHP 642
+E +G G F DV GK K + VAIK LK + R+F E IM + H
Sbjct: 250 LENQLGSGHFADVYSGKWKNHSK------VAIKILK-NNDALVLREFQLEVQIMKRLRHK 302
Query: 643 NVIFLQGVVTKCNPIMIITEFMENGSLDTFLRANDGK-FRVLQLVGMLRGIATGMQYLSE 701
++I L V T +P IITE +E G L FLR +G+ ++ L+ M +A GM YL
Sbjct: 303 HLISLFAVCTSSSPFYIITELIEKGDLLHFLRNPEGRSLQMESLIDMAAQVADGMAYLEA 362
Query: 702 MNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGGKIPVRWTAPEAIAFR 761
N IHRDLAARNVLV VCKIADFGL+R I+ + Y + KIP +WTAPEAI
Sbjct: 363 NNSIHRDLAARNVLVGDGYVCKIADFGLARIIK---EPVYLSDDKKIPYKWTAPEAIGHG 419
Query: 762 KFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEK-GYRLPAPMDCPEAVYQLML 820
++S SDVWS GI+ +E+++ G PY + +V I K YR+P+P CP+A+Y +M
Sbjct: 420 TYSSKSDVWSFGILLYEIVTHGGIPYPGVNTGEVYDLITKENYRMPSPPKCPQAIYNIMR 479
Query: 821 DCWQKERTHRPTFSSIVKTLD 841
CW+ E RP F + LD
Sbjct: 480 ACWRIESVDRPNFKVLKDELD 500
>UniRef50_P08069 Cluster: Insulin-like growth factor 1 receptor
precursor (EC 2.7.10.1) (Insulin-like growth factor I
receptor) (IGF-I receptor) (CD221 antigen) [Contains:
Insulin-like growth factor 1 receptor alpha chain;
Insulin-like growth factor 1 receptor beta chain]; n=47;
Euteleostomi|Rep: Insulin-like growth factor 1 receptor
precursor (EC 2.7.10.1) (Insulin-like growth factor I
receptor) (IGF-I receptor) (CD221 antigen) [Contains:
Insulin-like growth factor 1 receptor alpha chain;
Insulin-like growth factor 1 receptor beta chain] - Homo
sapiens (Human)
Length = 1367
Score = 192 bits (468), Expect = 4e-47
Identities = 104/277 (37%), Positives = 158/277 (57%), Gaps = 14/277 (5%)
Query: 575 EIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEAS 634
E+ IT+ +G G FG V G K PE VAIKT+ ++ R R +FL EAS
Sbjct: 993 EVAREKITMSRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVNEAASMRERIEFLNEAS 1052
Query: 635 IMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFR---------VLQL 685
+M +F +V+ L GVV++ P ++I E M G L ++LR+ + + ++
Sbjct: 1053 VMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSLRPEMENNPVLAPPSLSKM 1112
Query: 686 VGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRG 745
+ M IA GM YL+ ++HRDLAARN +V KI DFG++R+I T Y +G
Sbjct: 1113 IQMAGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDFGMTRDIYETD---YYRKG 1169
Query: 746 GK--IPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGY 803
GK +PVRW +PE++ FT+ SDVWS G+V WE+ + E+PY SN+ V++ + +G
Sbjct: 1170 GKGLLPVRWMSPESLKDGVFTTYSDVWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGG 1229
Query: 804 RLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTL 840
L P +CP+ +++LM CWQ RP+F I+ ++
Sbjct: 1230 LLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISSI 1266
>UniRef50_Q16832 Cluster: Discoidin domain-containing receptor 2
precursor; n=54; Euteleostomi|Rep: Discoidin
domain-containing receptor 2 precursor - Homo sapiens
(Human)
Length = 855
Score = 192 bits (468), Expect = 4e-47
Identities = 122/320 (38%), Positives = 177/320 (55%), Gaps = 41/320 (12%)
Query: 551 TGSRTYIDPHTYED----PNQAVREFAREIDASCITIEAIIGGGEFGDV--CR----GKL 600
TG TY P D + AV EF R++ +T + +G G+FG+V C K
Sbjct: 533 TGGNTYSVPAVTMDLLSGKDVAVEEFPRKL----LTFKEKLGEGQFGEVHLCEVEGMEKF 588
Query: 601 K-----LPASCGPEIDVAIKTLKPGSTERARRDFLAEASIMGQFEHPNVIFLQGVVTKCN 655
K L S + VA+K L+ + + AR DFL E IM + + PN+I L V +
Sbjct: 589 KDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLSVCITDD 648
Query: 656 PIMIITEFMENGSLDTFL------RANDGKFRVL---QLVGMLRGIATGMQYLSEMNYIH 706
P+ +ITE+MENG L+ FL ++ R + L M IA+GM+YLS +N++H
Sbjct: 649 PLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVH 708
Query: 707 RDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGGK--IPVRWTAPEAIAFRKFT 764
RDLA RN LV KIADFG+SR + S G Y G+ +P+RW + E+I KFT
Sbjct: 709 RDLATRNCLVGKNYTIKIADFGMSRNLYS---GDYYRIQGRAVLPIRWMSWESILLGKFT 765
Query: 765 SASDVWSMGIVCWEVMSF-GERPYWNWSNQDVIKSIEKGYR-------LPAPMDCPEAVY 816
+ASDVW+ G+ WE +F E+PY S++ VI++ + +R LP P CP++VY
Sbjct: 766 TASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVY 825
Query: 817 QLMLDCWQKERTHRPTFSSI 836
+LML CW+++ +RP+F I
Sbjct: 826 KLMLSCWRRDTKNRPSFQEI 845
>UniRef50_UPI0000D55B96 Cluster: PREDICTED: similar to
Tyrosine-protein kinase Src64B (Dsrc64) isoform 2; n=1;
Tribolium castaneum|Rep: PREDICTED: similar to
Tyrosine-protein kinase Src64B (Dsrc64) isoform 2 -
Tribolium castaneum
Length = 473
Score = 192 bits (467), Expect = 5e-47
Identities = 100/228 (43%), Positives = 141/228 (61%), Gaps = 9/228 (3%)
Query: 610 IDVAIKTLKPGSTERARRDFLAEASIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSL 669
I+VA+K L+ G+ + + FL EA+IM +F H ++ L GV ++ PI I+ E+M GSL
Sbjct: 228 IEVAVKMLREGTM--STQAFLQEAAIMKKFRHKRLVTLFGVCSEHEPIYIVQEYMSKGSL 285
Query: 670 DTFLRANDGK-FRVLQLVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFG 728
FLR ++GK LV + +A+GM+YL IHRDLAARNVL+ + KI DFG
Sbjct: 286 LDFLRKDEGKELEFEDLVYIAFQVASGMEYLESKQLIHRDLAARNVLIGENNIAKICDFG 345
Query: 729 LSREIESTADGAYTTR-GGKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPY 787
L+R IE D Y + G + PV+WTAPEAI + KF+ SDVWS GI E+ ++G+ PY
Sbjct: 346 LARVIE---DNEYCPKQGSRFPVKWTAPEAIVYGKFSIKSDVWSYGIFLMELFTYGQVPY 402
Query: 788 WNWSNQDVIKSIEKGYRLPAPMD--CPEAVYQLMLDCWQKERTHRPTF 833
++VI +EKGYR+ P P+ +Y +ML CW + +RPTF
Sbjct: 403 PGMHGREVIDMVEKGYRMGKPTSHVLPDEIYSIMLQCWDAKPENRPTF 450
>UniRef50_Q8JG38 Cluster: Fibroblast growth factor receptor 2
precursor; n=11; Eumetazoa|Rep: Fibroblast growth factor
receptor 2 precursor - Danio rerio (Zebrafish)
(Brachydanio rerio)
Length = 817
Score = 192 bits (467), Expect = 5e-47
Identities = 115/329 (34%), Positives = 178/329 (54%), Gaps = 26/329 (7%)
Query: 537 AKTSSNATTPLFAGTGSRT--YIDP-HTYEDPNQAVREFAREIDASCITIEAIIGGGEFG 593
+ +S +++TPL T R+ + DP Y+ P EF+R+ +T+ +G G FG
Sbjct: 434 SSSSMSSSTPLVRITTRRSSAHDDPIPEYDLPEDPRWEFSRDK----LTLGKPLGEGCFG 489
Query: 594 DVCRGK-LKLPASCGPE-IDVAIKTLKPGSTERARRDFLAEASIMGQF-EHPNVIFLQGV 650
V + L + E + VA+K LK +TE+ D ++E +M H N+I L G
Sbjct: 490 QVVMAEALGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGRHKNIINLLGA 549
Query: 651 VTKCNPIMIITEFMENGSLDTFLRA---------------NDGKFRVLQLVGMLRGIATG 695
T+ P+ +I E+ G+L +LRA +D LV +A G
Sbjct: 550 CTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDIARVSDEPLTFKDLVSCTYQVARG 609
Query: 696 MQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGGKIPVRWTAP 755
M+YL+ IHRDLAARNVLV V KIADFGL+R++ + D T G++PV+W AP
Sbjct: 610 MEYLASQKCIHRDLAARNVLVTESNVMKIADFGLARDVHNI-DYYKKTTNGRLPVKWMAP 668
Query: 756 EAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEAV 815
EA+ R +T SDVWS G++ WE+ + G PY +++ K +++G+R+ P +C +
Sbjct: 669 EALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNEL 728
Query: 816 YQLMLDCWQKERTHRPTFSSIVKTLDKLI 844
Y +M DCW +HRPTF +V+ LD+++
Sbjct: 729 YMMMKDCWHAISSHRPTFKQLVEDLDRIL 757
>UniRef50_A3EXK5 Cluster: Fibroblast growth factor receptor b; n=1;
Nematostella vectensis|Rep: Fibroblast growth factor
receptor b - Nematostella vectensis
Length = 591
Score = 191 bits (466), Expect = 7e-47
Identities = 108/283 (38%), Positives = 160/283 (56%), Gaps = 18/283 (6%)
Query: 575 EIDASCITIEAIIGGGEFGDVCRGK-LKLPASCGPEIDVAIKTLKPGSTERARRDFLAEA 633
E+D S I++ I+G G FG V + + LP + +VA+K L +TE D ++E
Sbjct: 268 ELDRSQISLLGILGEGAFGRVVKADAIGLP-NMPYRCNVAVKMLXEDATEHELADLVSEM 326
Query: 634 SIMGQF-EHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRANDG-------------- 678
+M +H N+I L G T+ P+ ++ E+ G+L FLRA
Sbjct: 327 EVMKTIGQHVNIINLIGACTQKGPLFVVVEYASQGNLRQFLRARRPIPEYANPLTEPPRE 386
Query: 679 KFRVLQLVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTAD 738
K +++ LV +A GM+YL IHRDLAARNVLV+ V KIADFGL+R+I D
Sbjct: 387 KLKLVDLVSFSYQVARGMEYLESKKCIHRDLAARNVLVSDNHVIKIADFGLARDIHDI-D 445
Query: 739 GAYTTRGGKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKS 798
T G++PV+W A EA+ R +T+ SDVW+ GI+ WE+++FG PY + +
Sbjct: 446 YYRKTTDGRLPVKWMALEALFDRVYTAQSDVWAYGILMWEIVTFGGSPYPGIPLWKLFEL 505
Query: 799 IEKGYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLD 841
+++GYR+ P++C + VY LML CW + RPTF+ IVK +D
Sbjct: 506 LKEGYRMEQPVNCQDDVYALMLRCWHENPNQRPTFAEIVKEMD 548
>UniRef50_P00534 Cluster: Tyrosine-protein kinase transforming
protein erbB; n=8; root|Rep: Tyrosine-protein kinase
transforming protein erbB - Avian leukosis virus (ALV)
Length = 634
Score = 191 bits (466), Expect = 7e-47
Identities = 106/296 (35%), Positives = 160/296 (54%), Gaps = 8/296 (2%)
Query: 554 RTYIDPHTY--EDPNQAVREFAREIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEID 611
R ++P T E PNQA +E + + + +G G FG V +G L +P +I
Sbjct: 106 RELVEPLTPSGEAPNQAHLRILKETEFKKVKV---LGSGAFGTVYKG-LWIPEGEKVKIP 161
Query: 612 VAIKTLKPGSTERARRDFLAEASIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDT 671
VAIK L+ ++ +A ++ L EA +M ++P+V L G+ + + +IT+ M G L
Sbjct: 162 VAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLT-STVQLITQLMPYGCLLD 220
Query: 672 FLRANDGKFRVLQLVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSR 731
++R + L+ IA GM YL E +HRDLAARNVLV + KI DFGL++
Sbjct: 221 YIREHKDNIGSQYLLNWCVQIAKGMNYLEERRLVHRDLAARNVLVKTPQHVKITDFGLAK 280
Query: 732 EIESTADGAYTTRGGKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWS 791
+ + + Y GGK+P++W A E+I R +T SDVWS G+ WE+M+FG +PY
Sbjct: 281 LLGAD-EKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIP 339
Query: 792 NQDVIKSIEKGYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLIRCP 847
++ +EKG RLP P C VY +M+ CW + RP F ++ K+ R P
Sbjct: 340 ASEISSVLEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIAEFSKMARDP 395
>UniRef50_Q7PYY7 Cluster: ENSANGP00000019144; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000019144 - Anopheles gambiae
str. PEST
Length = 687
Score = 191 bits (465), Expect = 9e-47
Identities = 108/325 (33%), Positives = 169/325 (52%), Gaps = 18/325 (5%)
Query: 536 PAKTSSNATTPLFAGTGSRTYIDPHTYEDPNQAVREFAREIDASCITIEAIIGGGEFGDV 595
P S+ T+P T E+ N ++ + E + + I+G G FG V
Sbjct: 339 PMAFSNRYTSPWERDTNGHLQATSQLSEESNGSIVKDRWEFPRHRLKVFNILGEGAFGQV 398
Query: 596 CRGKLK-LPASCGPEIDVAIKTLKPGSTERARRDFLAEASIMGQFE-HPNVIFLQGVVTK 653
R + + G + A+KTLK ++E R D L+E ++ E H NV+ L G T+
Sbjct: 399 WRCEATDIDGHEGVSV-TAVKTLKENASEAERNDLLSELQVLKSLEPHINVVRLLGCCTE 457
Query: 654 CNPIMIITEFMENGSLDTFLRAN---------DGKFRVL---QLVGMLRGIATGMQYLSE 701
+PI +I E++ G L TFLR + GK ++L L + +A GM +L+
Sbjct: 458 KDPIFVILEYVNMGKLQTFLRNSRVEKHYGNTHGKSKILTSGDLTSFMYQVARGMDFLTS 517
Query: 702 MNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRG-GKIPVRWTAPEAIAF 760
IHRDLAARN+L+ CK+ADFG +R+I ++ Y + G++P+RW A E++
Sbjct: 518 RGIIHRDLAARNILITDDHTCKVADFGFARDIVTSK--VYERKSEGRLPIRWMATESLYD 575
Query: 761 RKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEAVYQLML 820
FT SD+WS GI+ WE+++ G PY + DV++ + GYRL P C +Y +M
Sbjct: 576 NIFTVKSDIWSFGILMWEIVTLGSTPYPGIAAADVMRKVRDGYRLEKPEHCRRELYNIMF 635
Query: 821 DCWQKERTHRPTFSSIVKTLDKLIR 845
CW + RP F +V+ LD+L++
Sbjct: 636 YCWAADPNERPGFPEVVEMLDRLLQ 660
>UniRef50_P00533 Cluster: Epidermal growth factor receptor
precursor; n=124; root|Rep: Epidermal growth factor
receptor precursor - Homo sapiens (Human)
Length = 1210
Score = 191 bits (465), Expect = 9e-47
Identities = 106/296 (35%), Positives = 160/296 (54%), Gaps = 8/296 (2%)
Query: 554 RTYIDPHTY--EDPNQAVREFAREIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEID 611
R ++P T E PNQA+ +E + I + +G G FG V +G L +P +I
Sbjct: 686 RELVEPLTPSGEAPNQALLRILKETEFKKIKV---LGSGAFGTVYKG-LWIPEGEKVKIP 741
Query: 612 VAIKTLKPGSTERARRDFLAEASIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDT 671
VAIK L+ ++ +A ++ L EA +M ++P+V L G+ + + +IT+ M G L
Sbjct: 742 VAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLT-STVQLITQLMPFGCLLD 800
Query: 672 FLRANDGKFRVLQLVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSR 731
++R + L+ IA GM YL + +HRDLAARNVLV + KI DFGL++
Sbjct: 801 YVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAK 860
Query: 732 EIESTADGAYTTRGGKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWS 791
+ + Y GGK+P++W A E+I R +T SDVWS G+ WE+M+FG +PY
Sbjct: 861 LL-GAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIP 919
Query: 792 NQDVIKSIEKGYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLIRCP 847
++ +EKG RLP P C VY +M+ CW + RP F ++ K+ R P
Sbjct: 920 ASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDP 975
>UniRef50_Q9VBW3 Cluster: Tyrosine kinase receptor Cad96Ca
precursor; n=2; Diptera|Rep: Tyrosine kinase receptor
Cad96Ca precursor - Drosophila melanogaster (Fruit fly)
Length = 773
Score = 191 bits (465), Expect = 9e-47
Identities = 103/273 (37%), Positives = 150/273 (54%), Gaps = 16/273 (5%)
Query: 586 IIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEASIMGQFE-HPNV 644
I+G G FG V R + VA+KTLK +TE R+D L+E +M E H NV
Sbjct: 475 ILGEGAFGQVWRCEATNINGNEGITTVAVKTLKESATEVDRKDLLSELEVMKSLEPHINV 534
Query: 645 IFLQGVVTKCNPIMIITEFMENGSLDTFLRAN---------DGKFRVL---QLVGMLRGI 692
+ L G T +P +I E++ G L T+LR++ GK VL L + +
Sbjct: 535 VHLLGCCTDKDPTFVILEYVNRGKLQTYLRSSRAERHYGNTHGKSNVLTSCDLTSFMYQV 594
Query: 693 ATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRG-GKIPVR 751
A GM YL+ IHRDLAARN+L+ CK+ADFG +R++ ++ Y + GK+P+R
Sbjct: 595 AKGMDYLTSRGIIHRDLAARNILITDDHTCKVADFGFARDVITSK--IYERKSEGKLPIR 652
Query: 752 WTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDC 811
W A E++ F+ SD+WS GI+ WE+++ G PY S DV++ + GYRL P C
Sbjct: 653 WMATESLYDNIFSVKSDIWSFGILMWEIVTLGSTPYPGISAADVMRKVRDGYRLEKPEHC 712
Query: 812 PEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLI 844
+Y +M CW + RP F+ I++ LDKL+
Sbjct: 713 RRELYNIMYYCWSHDPQERPLFAEIIQMLDKLL 745
>UniRef50_UPI00004D7E5F Cluster: Proto-oncogene tyrosine-protein
kinase MER precursor (EC 2.7.10.1) (C- mer) (Receptor
tyrosine kinase MerTK).; n=1; Xenopus tropicalis|Rep:
Proto-oncogene tyrosine-protein kinase MER precursor (EC
2.7.10.1) (C- mer) (Receptor tyrosine kinase MerTK). -
Xenopus tropicalis
Length = 763
Score = 190 bits (464), Expect = 1e-46
Identities = 107/282 (37%), Positives = 165/282 (58%), Gaps = 18/282 (6%)
Query: 576 IDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGS-TERARRDFLAEAS 634
++ + + + ++G GEFG V G+L+ S G VA+KT+K + ++R +FL+EA+
Sbjct: 466 VERNLLNLGKVLGEGEFGSVMEGELQY--SDGTNHKVAVKTMKMDNFSQREIEEFLSEAA 523
Query: 635 IMGQFEHPNVIFLQGVVTKCNPI-----MIITEFMENGSLDTFL---RANDGKFRV--LQ 684
M F HPNVI L GV + P M+I FM+ G L +FL R G V
Sbjct: 524 CMKDFNHPNVIRLLGVCLEVGPRRIPKPMVILPFMKYGDLHSFLLSSRIGSGPQHVPLRT 583
Query: 685 LVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTR 744
LV + IATGM+YLS N++HRDLAARN ++ + +ADFGLS++I S G Y +
Sbjct: 584 LVKFMIDIATGMEYLSSRNFLHRDLAARNCMLRDDMTVCVADFGLSKKIYS---GDYYRQ 640
Query: 745 G--GKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKG 802
G K+PV+W A E++A R +T SDVW+ G+ WE+ + G PY N ++ + G
Sbjct: 641 GRIAKMPVKWIAVESLADRIYTVKSDVWAFGVTMWEISTRGMTPYPGVQNHEIYDYLLVG 700
Query: 803 YRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLI 844
+RL P +C + +Y +M CW + T RP+F+++ + L+K++
Sbjct: 701 HRLKQPPECLDDLYTVMYQCWLSDPTCRPSFTALRENLEKIV 742
>UniRef50_UPI0000D56EE8 Cluster: PREDICTED: similar to CG14992-PA;
n=3; Tribolium castaneum|Rep: PREDICTED: similar to
CG14992-PA - Tribolium castaneum
Length = 1000
Score = 190 bits (463), Expect = 2e-46
Identities = 105/264 (39%), Positives = 143/264 (54%), Gaps = 6/264 (2%)
Query: 576 IDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERAR--RDFLAEA 633
I S IT+ +G G FG V RG+ P G + VA+K LK + + DF+ E
Sbjct: 106 IPESNITLSIKLGDGSFGVVRRGEWTSPN--GRVLPVAVKILKADALSQPGVFEDFIKEV 163
Query: 634 SIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFRVLQLVGMLRGIA 693
M HPN+I L GVV P+M++TE GSL +LR + V L +A
Sbjct: 164 QAMHVLSHPNLIRLYGVVLS-QPMMMVTELANLGSLLDYLRKQCQQTPVPMLCEYATQVA 222
Query: 694 TGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGGKIPVRWT 753
TGM YL ++HRDLA RNVL+ S KI DFGL R + D T K+P W
Sbjct: 223 TGMAYLESKRFLHRDLACRNVLLASADKIKIGDFGLMRALPQEEDCYVMTEHKKVPFPWC 282
Query: 754 APEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEK-GYRLPAPMDCP 812
APE++ R+F+ ASD W G+ WE+ +FGE P+ ++++ I+K G RL P CP
Sbjct: 283 APESLRSRQFSHASDTWMFGVTVWEMFTFGEDPWMGLIGSEILRKIDKEGERLHQPEACP 342
Query: 813 EAVYQLMLDCWQKERTHRPTFSSI 836
AVY ++L CW K T RPTF+++
Sbjct: 343 PAVYSILLQCWLKNPTERPTFAAL 366
>UniRef50_Q17MF5 Cluster: Tyrosine-protein kinase; n=2;
Culicidae|Rep: Tyrosine-protein kinase - Aedes aegypti
(Yellowfever mosquito)
Length = 747
Score = 190 bits (463), Expect = 2e-46
Identities = 106/268 (39%), Positives = 154/268 (57%), Gaps = 18/268 (6%)
Query: 575 EIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEAS 634
EI + ++ IG GEFGDV G LK G + VA+K LK RA FLAEA
Sbjct: 483 EIKMEDLQLKENIGKGEFGDVMLGILK-----GEK--VAVKVLKDAG--RASNKFLAEAG 533
Query: 635 IMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFRVLQL--VGMLRGI 692
+M EH N++ G+V I ++TE+M GSL +LR+ G+ + + +
Sbjct: 534 VMTTLEHENLVKFIGLVFHDKYIYLVTEYMSKGSLVDYLRSR-GRQHITRRDQINFAFDT 592
Query: 693 ATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGGKIPVRW 752
+GM+YL IHRDLAARNVL++ + V K++DFGL+R+ TAD + K+P++W
Sbjct: 593 CSGMEYLEMKKVIHRDLAARNVLISEECVAKVSDFGLARDERYTADIS------KLPIKW 646
Query: 753 TAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCP 812
TAPEA+ KF++ +D+WS GI+ WE+ SFG PY DV+K + GY++ AP CP
Sbjct: 647 TAPEALKEGKFSNKTDMWSFGILLWEIYSFGRVPYPRIPLADVVKHVGSGYKMEAPEGCP 706
Query: 813 EAVYQLMLDCWQKERTHRPTFSSIVKTL 840
+Y++M W RPTF+ + + L
Sbjct: 707 PEIYEMMRQAWDLVPEKRPTFAELKRRL 734
>UniRef50_P08923 Cluster: Leukocyte tyrosine kinase receptor
precursor; n=8; Amniota|Rep: Leukocyte tyrosine kinase
receptor precursor - Mus musculus (Mouse)
Length = 888
Score = 190 bits (463), Expect = 2e-46
Identities = 106/288 (36%), Positives = 162/288 (56%), Gaps = 16/288 (5%)
Query: 575 EIDASCITIEAIIGGGEFGDVCRGKLK-LPASCGPEIDVAIKTLKPGSTERARRDFLAEA 633
E+ + +T+ +G G FG+V G + LP P + VAIKTL + + DFL EA
Sbjct: 500 EVSPANVTLLRALGHGAFGEVYEGLVTGLPGDSSP-LPVAIKTLPELCSHQDELDFLMEA 558
Query: 634 SIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLR---ANDGKFRVLQLVGMLR 690
I+ +F H N++ G+ + P +I+ E M G + +FLR + G+ L + +L+
Sbjct: 559 LIISKFSHQNIVRCVGLSFRSAPRLILLELMSGGDMKSFLRHSRPHPGQLAPLTMQDLLQ 618
Query: 691 ---GIATGMQYLSEMNYIHRDLAARNVLVN---SQLVCKIADFGLSREIESTADGAYTTR 744
IA G YL E ++IHRD+AARN L++ + V KI DFG++R+I + Y +
Sbjct: 619 LAQDIAQGCHYLEENHFIHRDIAARNCLLSCSGASRVAKIGDFGMARDIYQAS---YYRK 675
Query: 745 GGK--IPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKG 802
GG+ +PV+W PEA+ FTS +D WS G++ WE+ S G PY +NQ+V+ I G
Sbjct: 676 GGRTLLPVKWMPPEALLEGLFTSKTDSWSFGVLLWEIFSLGYMPYPGHTNQEVLDFIATG 735
Query: 803 YRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLIRCPDTL 850
R+ P +CP VY++M CWQ + RP F SI++ + + PD L
Sbjct: 736 NRMDPPRNCPGPVYRIMTQCWQHQPELRPDFGSILERIQYCTQDPDVL 783
>UniRef50_Q4SII9 Cluster: Chromosome 5 SCAF14581, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 5
SCAF14581, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 921
Score = 190 bits (462), Expect = 2e-46
Identities = 92/205 (44%), Positives = 128/205 (62%), Gaps = 6/205 (2%)
Query: 635 IMGQFEHPNVIFLQGVVTKCNPIMIITEFME-NGSLDTFLRANDGKFRVLQLVGMLRGIA 693
I+ Q++HPNV+ L GV T+ PI I+ E ++ +G TFLR + LV M +A
Sbjct: 710 ILKQYDHPNVVKLIGVCTQKQPIYIVMELIQGSGDFLTFLRNQGRDLKPKALVKMAENVA 769
Query: 694 TGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGG--KIPVR 751
+GM YL IHRDLAARN LV KI+DFG+SR+ + DG Y GG +IP++
Sbjct: 770 SGMAYLESKKCIHRDLAARNCLVAENNSVKISDFGMSRQDD---DGVYLAEGGLRQIPIK 826
Query: 752 WTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDC 811
WTAPEA+ + ++T+ SDVWS GI+ WE S G PY + SNQ +EKGYR+PAP C
Sbjct: 827 WTAPEALNYGRYTTQSDVWSFGILLWETFSLGLTPYMSMSNQQTRDEVEKGYRMPAPHAC 886
Query: 812 PEAVYQLMLDCWQKERTHRPTFSSI 836
P + ++M +CWQ + +RP+F +
Sbjct: 887 PVEIARIMNNCWQYDPQNRPSFKKL 911
>UniRef50_Q5K4G5 Cluster: Receptor tyrosine kinase; n=1; Suberites
domuncula|Rep: Receptor tyrosine kinase - Suberites
domuncula (Sponge)
Length = 715
Score = 190 bits (462), Expect = 2e-46
Identities = 102/263 (38%), Positives = 145/263 (55%), Gaps = 9/263 (3%)
Query: 587 IGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEASIMGQF-EHPNVI 645
+G G FG V + +L P S I VA+K LK ++ +D + E ++ EH NV+
Sbjct: 393 LGSGAFGVVKKAELFDPISQTTSI-VAVKMLKESASTEDEKDIIMELKVLYHVGEHCNVV 451
Query: 646 FLQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFR----VLQLVGMLRGIATGMQYLSE 701
G + +I E+ E G+L FLR+ G + V V + +A GM YL+
Sbjct: 452 SFLGASVHKGKLHLIVEYCERGNLLQFLRSKRGDMKSPLSVQNQVAIASQVANGMAYLAS 511
Query: 702 MNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGGKIPVRWTAPEAIAFR 761
IHRDLAARNVL+ L K+ADFGL+R++ S+ Y G ++P++W APE I
Sbjct: 512 KRCIHRDLAARNVLITKDLTLKVADFGLARKMYSSV---YRPSGKRLPIKWMAPEGILDG 568
Query: 762 KFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEAVYQLMLD 821
TS SDVWS GI+ WE+M+ G PY S VI+ IE GYR+P P CP+ +Y +M
Sbjct: 569 VCTSKSDVWSFGILLWEIMTLGRTPYPGRSAHWVIRDIENGYRMPQPDGCPDKLYSVMKC 628
Query: 822 CWQKERTHRPTFSSIVKTLDKLI 844
CWQ RP F+ + +LD ++
Sbjct: 629 CWQMNPIARPEFTELTNSLDNVV 651
>UniRef50_Q008W6 Cluster: Gamma-carboxyglutamic acid protein 1; n=2;
Ascidiacea|Rep: Gamma-carboxyglutamic acid protein 1 -
Ciona intestinalis (Transparent sea squirt)
Length = 556
Score = 190 bits (462), Expect = 2e-46
Identities = 101/277 (36%), Positives = 156/277 (56%), Gaps = 11/277 (3%)
Query: 576 IDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEASI 635
++ + + +I G FGDV RGKL+ + DVA+K+LK FL E +
Sbjct: 167 VERERLQLGEVITSGNFGDVYRGKLRSRQNTWH--DVAVKSLKSLENHEDVEKFLREGVM 224
Query: 636 MGQFEHPNVIFLQGVVT-------KCNPIMIITEFMENGSLDTFLRANDGKFRVLQLVGM 688
M +H NV+ L GV + +P++I+ FMENG L TFLR + VL+L+
Sbjct: 225 MRGLDHRNVLALIGVCVDGEVERLQTSPLIILP-FMENGDLRTFLRDGNNVLTVLKLLKF 283
Query: 689 LRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGGKI 748
+ +A GM+YL+E ++HRDLAARN +V+ K+ADFGLSR++ D ++ ++
Sbjct: 284 CKDVAMGMEYLAEKKFVHRDLAARNCMVDKNWCVKVADFGLSRDLFDR-DYYRSSVKTQL 342
Query: 749 PVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAP 808
P++W PE+I + ++ SDVWS GIVCWE+M+ G PY +++ + +G R+ P
Sbjct: 343 PLKWMPPESIKYGRYGEKSDVWSYGIVCWEIMTRGAIPYPTVQAVAILQYLSEGNRMERP 402
Query: 809 MDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLIR 845
CP +Y+ M CW + RPTF +V K++R
Sbjct: 403 ECCPHKLYKTMEKCWLDDTERRPTFEELVTITTKIVR 439
>UniRef50_P42679 Cluster: Megakaryocyte-associated tyrosine-protein
kinase; n=38; Euteleostomi|Rep: Megakaryocyte-associated
tyrosine-protein kinase - Homo sapiens (Human)
Length = 507
Score = 190 bits (462), Expect = 2e-46
Identities = 109/293 (37%), Positives = 161/293 (54%), Gaps = 21/293 (7%)
Query: 557 IDPHTYEDPNQAVREFARE---IDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVA 613
+ P A E AR ++ +T+ A IG GEFG V +G+ G + VA
Sbjct: 208 VRPKRKHGTKSAEEELARAGWLLNLQHLTLGAQIGEGEFGAVLQGEY-----LGQK--VA 260
Query: 614 IKTLKPGSTERARRDFLAEASIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFL 673
+K +K T +A FL E ++M + +H N++ L GV+ + I+ E + G+L FL
Sbjct: 261 VKNIKCDVTAQA---FLDETAVMTKMQHENLVRLLGVILH-QGLYIVMEHVSKGNLVNFL 316
Query: 674 RANDGKF-RVLQLVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSRE 732
R QL+ +A GM+YL +HRDLAARN+LV+ LV K++DFGL++
Sbjct: 317 RTRGRALVNTAQLLQFSLHVAEGMEYLESKKLVHRDLAARNILVSEDLVAKVSDFGLAKA 376
Query: 733 IESTADGAYTTRGGKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSN 792
D + ++PV+WTAPEA+ KFTS SDVWS G++ WEV S+G PY S
Sbjct: 377 ERKGLDSS------RLPVKWTAPEALKHGKFTSKSDVWSFGVLLWEVFSYGRAPYPKMSL 430
Query: 793 QDVIKSIEKGYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLIR 845
++V +++EKGYR+ P CP V+ LM CW+ E RP F + + L + +R
Sbjct: 431 KEVSEAVEKGYRMEPPEGCPGPVHVLMSSCWEAEPARRPPFRKLAEKLARELR 483
>UniRef50_Q6NP28 Cluster: LP09923p; n=6; Endopterygota|Rep: LP09923p
- Drosophila melanogaster (Fruit fly)
Length = 847
Score = 189 bits (460), Expect = 4e-46
Identities = 104/259 (40%), Positives = 149/259 (57%), Gaps = 19/259 (7%)
Query: 587 IGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEASIMGQFEHPNVIF 646
IG GEFGDV G L+ VA+K LK E A + FLAEAS+M EH N++
Sbjct: 601 IGKGEFGDVMLGILR-------NEKVAVKMLKD---EGAVQKFLAEASVMTTLEHDNLVK 650
Query: 647 LQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFRVLQLVGMLRGI--ATGMQYLSEMNY 704
G+V + ++TE+M GSL +LR+ G+ + + ++ A+GM+YL
Sbjct: 651 FIGLVFTSKHLYLVTEYMSKGSLVDYLRSR-GRQHITKKDQIIFAYDTASGMEYLEAKKV 709
Query: 705 IHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGGKIPVRWTAPEAIAFRKFT 764
+HRDLAARNVL++ V K++DFGL+RE Y GK+P++WTAPEA+ +F+
Sbjct: 710 VHRDLAARNVLISEDCVAKVSDFGLARE------ECYNLDVGKLPIKWTAPEALKNGRFS 763
Query: 765 SASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEAVYQLMLDCWQ 824
+ SD+WS GI+ WE+ SFG PY DV+K +E GY++ AP CP +Y++M W
Sbjct: 764 NKSDMWSFGILLWEIYSFGRVPYPRIPLADVVKHVEVGYKMEAPEGCPPEIYEMMRQAWD 823
Query: 825 KERTHRPTFSSIVKTLDKL 843
RPTF+ + L L
Sbjct: 824 LNPAKRPTFAELKVKLQLL 842
>UniRef50_Q9XVQ7 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 442
Score = 188 bits (459), Expect = 5e-46
Identities = 102/280 (36%), Positives = 163/280 (58%), Gaps = 16/280 (5%)
Query: 576 IDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERAR-----RDFL 630
+ + + +E I+G G FG+V RG+++ PA G I VA+KTLK ERAR FL
Sbjct: 131 LPSEAVVLETIVGKGYFGNVYRGRMRDPA--GRLIPVAVKTLKG---ERARDIAHIEKFL 185
Query: 631 AEASIMGQFEHPNVIFLQGV-VTKCNPIMIITEFMENGSLDTFLRANDGKFRVLQLVGML 689
E +M +HP+V+ L G+ ++ ++ +ME G L T++ + VL+L+
Sbjct: 186 REGVVMKHLDHPHVLSLLGISISPAGNPWVVLPYMEGGDLKTYIADPNRALCVLELLDFA 245
Query: 690 RGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREI---ESTADGAYTTRGG 746
+A GM YL+ +++HRDLAARN ++++ + K+ADFGL+ ++ ES D + T
Sbjct: 246 HQVAQGMSYLAAQHFVHRDLAARNCMISADRIVKVADFGLAVDLLDKESYIDES-ETGPA 304
Query: 747 KIPVRWTAPEAIAFRK-FTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRL 805
++P++W APE++ R+ F+SA+DVWS G++ WE+++ PY SN V +E G RL
Sbjct: 305 RLPLKWLAPESLRDRRVFSSATDVWSFGVLMWELLTRAASPYGEVSNTKVRHYLETGMRL 364
Query: 806 PAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLIR 845
P P CP+ +Y LM CW+ RP F + L L++
Sbjct: 365 PQPTHCPDIIYDLMQCCWRSTPEDRPDFVFLSHRLRALLQ 404
>UniRef50_UPI00015B6133 Cluster: PREDICTED: similar to protein
tyrosine kinase; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to protein tyrosine kinase - Nasonia
vitripennis
Length = 739
Score = 188 bits (458), Expect = 6e-46
Identities = 106/280 (37%), Positives = 153/280 (54%), Gaps = 5/280 (1%)
Query: 559 PHTYEDPNQAVREFAREIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLK 618
P E+ N+ V + I + ++G GEFG V G P+ G + VAIK L+
Sbjct: 442 PAIIENDNETVPLTQVFVPGENIILGEVLGEGEFGAVYEGLFDSPS--GTQEPVAIKMLR 499
Query: 619 PGSTERARRDFLAEASIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRANDG 678
R +FL EA +M F H ++ L G ++ P++++ E + GS+ +L
Sbjct: 500 DTHNIATREEFLREARLMMTFNHHCIVKLIGF-SEGPPLLMVQELVSLGSMLAYLLEFPD 558
Query: 679 KFRV-LQLVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTA 737
+ +L IA GM+YL E+ +HRDLAARN+L+ S+ KI+DFGLSR S
Sbjct: 559 RINPNYELKVWASQIACGMKYLEEIRLVHRDLAARNILLASKHQAKISDFGLSRTFGSN- 617
Query: 738 DGAYTTRGGKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIK 797
D T GGK P++W APE+ + F+ ASDVWS GI WE+ S+GE+PY + +VI
Sbjct: 618 DYYKATAGGKWPIKWYAPESYNYGTFSHASDVWSYGITLWEMFSYGEQPYGDRRGTEVID 677
Query: 798 SIEKGYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIV 837
+EKG RL P CP+ VY++M CW RPTF ++
Sbjct: 678 LVEKGDRLAQPEQCPDHVYKVMQKCWSYSPADRPTFQELL 717
>UniRef50_UPI00004D86FC Cluster: Tyrosine-protein kinase Tec (EC
2.7.10.2).; n=1; Xenopus tropicalis|Rep:
Tyrosine-protein kinase Tec (EC 2.7.10.2). - Xenopus
tropicalis
Length = 647
Score = 188 bits (458), Expect = 6e-46
Identities = 98/252 (38%), Positives = 150/252 (59%), Gaps = 12/252 (4%)
Query: 575 EIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEAS 634
EI+ S +T +G G FG V GK + + VAIK ++ G+ + DF+ EA
Sbjct: 406 EINPSELTFMKELGSGLFGVVRLGKWRA------QYKVAIKAIREGAM--SEEDFIEEAK 457
Query: 635 IMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFRVLQLVGMLRGIAT 694
+M + H ++ L GV T+ PI I+TEFME+G L +LR G+F L+ M + +
Sbjct: 458 VMMKLTHLKLVQLYGVCTQQRPIYIVTEFMEHGCLLNYLRQRHGQFSPDILLSMCQDVCE 517
Query: 695 GMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTR-GGKIPVRWT 753
M YL + N+IHRDLAARN LVN V K++DFG++R + D YT+ G K PV+W+
Sbjct: 518 AMSYLEQNNFIHRDLAARNCLVNDAGVVKVSDFGMTRYV---LDDQYTSSCGAKFPVKWS 574
Query: 754 APEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCPE 813
PE + +F+S SDVWS G++ WEV + G+ P+ ++SN +V++ + +G RL P +
Sbjct: 575 PPEVFNYSRFSSKSDVWSFGVLMWEVFTEGKMPFESYSNVEVVEMVTRGERLYRPKLATK 634
Query: 814 AVYQLMLDCWQK 825
+Y +M+ CW +
Sbjct: 635 IIYSVMVACWHE 646
>UniRef50_Q16UV1 Cluster: Protein kinase protein; n=3;
Culicidae|Rep: Protein kinase protein - Aedes aegypti
(Yellowfever mosquito)
Length = 1081
Score = 188 bits (458), Expect = 6e-46
Identities = 105/283 (37%), Positives = 146/283 (51%), Gaps = 9/283 (3%)
Query: 581 ITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERAR--RDFLAEASIMGQ 638
+T+ +G G FG V RG+ P G + VA+K LK + + DF E M
Sbjct: 119 VTMSVKLGDGSFGVVRRGEWNAPG--GQIVPVAVKILKADTLAQPGVIEDFFKEVQAMHT 176
Query: 639 FEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFRVLQLVGMLRGIATGMQY 698
HPN++ L GVV P+M++TE NGSL LR + + +ATGM Y
Sbjct: 177 LNHPNLVRLHGVVLS-QPMMMVTELAANGSLLDTLRKQCKNTSLTTIWNWSVQVATGMAY 235
Query: 699 LSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGGKIPVRWTAPEAI 758
L ++HRDLA RNVL+ S KI DFGL R + D T K+P W APE++
Sbjct: 236 LESKRFLHRDLACRNVLLASGNKIKIGDFGLMRALPQQEDCYVMTEHKKVPFPWCAPESL 295
Query: 759 AFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEK-GYRLPAPMDCPEAVYQ 817
+R+F+ ASD W + WE+ +FGE P+ + +++ I++ G RL P CP VYQ
Sbjct: 296 RYRQFSHASDTWMFAVTLWEMFTFGEDPWVGLNGSQILRKIDREGERLHHPDACPPDVYQ 355
Query: 818 LMLDCWQKERTHRPTFSSIVKTLDKLIRCPDTLRKIAQNRSAD 860
LML CW K RPTF++I + L P + + N AD
Sbjct: 356 LMLQCWDKSPAERPTFAAIKEFLS---ATPPPIYRAVMNYKAD 395
>UniRef50_Q8IXC7 Cluster: Isoform of FGFR2; n=23; Euteleostomi|Rep:
Isoform of FGFR2 - Homo sapiens (Human)
Length = 709
Score = 188 bits (458), Expect = 6e-46
Identities = 113/325 (34%), Positives = 170/325 (52%), Gaps = 31/325 (9%)
Query: 538 KTSSNATTPLFAGTGSRTYIDPHTYEDPNQAVREFAREIDASCITIEAIIGGGEFGDVCR 597
+ SS A TP+ AG YE P EF R+ +T+ +G G FG V
Sbjct: 338 RLSSTADTPMLAGVSE--------YELPEDPKWEFPRDK----LTLGKPLGEGCFGQVVM 385
Query: 598 GKLKLPASCGPE--IDVAIKTLKPGSTERARRDFLAEASIMGQF-EHPNVIFLQGVVTKC 654
+ P+ + VA+K LK +TE+ D ++E +M +H N+I L G T+
Sbjct: 386 AEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQD 445
Query: 655 NPIMIITEFMENGSLDTFLRAN---------------DGKFRVLQLVGMLRGIATGMQYL 699
P+ +I E+ G+L +LRA + + LV +A GM+YL
Sbjct: 446 GPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYL 505
Query: 700 SEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGGKIPVRWTAPEAIA 759
+ IHRDLAARNVLV V KIADFGL+R+I + D T G++PV+W APEA+
Sbjct: 506 ASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNI-DYYKKTTNGRLPVKWMAPEALF 564
Query: 760 FRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEAVYQLM 819
R +T SDVWS G++ WE+ + G PY +++ K +++G+R+ P +C +Y +M
Sbjct: 565 DRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMM 624
Query: 820 LDCWQKERTHRPTFSSIVKTLDKLI 844
DCW + RPTF +V+ LD+++
Sbjct: 625 RDCWHAVPSQRPTFKQLVEDLDRIL 649
>UniRef50_UPI0000ECD739 Cluster: Cytoplasmic tyrosine-protein kinase
BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in
chromosome X protein) (Epithelial and endothelial
tyrosine kinase) (ETK) (NTK38).; n=2; Gallus gallus|Rep:
Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2)
(Bone marrow tyrosine kinase gene in chromosome X
protein) (Epithelial and endothelial tyrosine kinase)
(ETK) (NTK38). - Gallus gallus
Length = 633
Score = 188 bits (457), Expect = 8e-46
Identities = 96/259 (37%), Positives = 149/259 (57%), Gaps = 12/259 (4%)
Query: 587 IGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEASIMGQFEHPNVIF 646
+G G+FG V GK K DVA+K +K G + +F+ EA M + HP ++
Sbjct: 378 LGSGQFGAVHLGKWK------GLYDVAVKMIKEGVV--SEDEFVEEAQTMMKLNHPKLVR 429
Query: 647 LQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFRVLQLVGMLRGIATGMQYLSEMNYIH 706
L GV +K PI ++ E+M NGSL ++L+ + + + LQL+ + + M +L IH
Sbjct: 430 LYGVCSKLYPIYLVMEYMPNGSLLSYLQIHGKELQPLQLLEICYDVCDAMAFLESCQLIH 489
Query: 707 RDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTR-GGKIPVRWTAPEAIAFRKFTS 765
RDLAARN LV+S L K++DFG+++ + D Y + G K PV+W+APE + KF+S
Sbjct: 490 RDLAARNCLVDSNLTVKLSDFGMTKYV---LDDLYVSSLGTKFPVKWSAPEVFHYTKFSS 546
Query: 766 ASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEAVYQLMLDCWQK 825
SDVW+ GI+ WEV + G++PY + N VI+ + +GYRL P + YQ+M +CW +
Sbjct: 547 KSDVWAFGILMWEVFTLGKQPYELYDNMQVIEKVSQGYRLYRPQLVSDITYQIMYNCWHE 606
Query: 826 ERTHRPTFSSIVKTLDKLI 844
RP F ++ + +
Sbjct: 607 LPEKRPAFHQLLSFFEDAV 625
>UniRef50_UPI00015B5959 Cluster: PREDICTED: similar to insulin
receptor; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to insulin receptor - Nasonia vitripennis
Length = 1714
Score = 187 bits (456), Expect = 1e-45
Identities = 100/263 (38%), Positives = 150/263 (57%), Gaps = 10/263 (3%)
Query: 587 IGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEASIMGQFEHPNVIF 646
+G G FG V G K PE+ A+KT+ +T+R R +FL EAS+M F +V+
Sbjct: 1135 LGNGSFGMVYEGIAKDVVKGKPEMRCAVKTVNENATDRERVEFLNEASVMKGFNTHHVVR 1194
Query: 647 LQGVVTKCNPIMIITEFMENGSLDTFLRANDGKF---------RVLQLVGMLRGIATGMQ 697
L GVV++ P +++ E M NG L T+LR++ + +++ M IA GM
Sbjct: 1195 LLGVVSQGQPTLVVMELMVNGDLKTYLRSHRPDVCENFSRQPPTLNRIMRMALEIADGMA 1254
Query: 698 YLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGGKIPVRWTAPEA 757
YL+ ++HRDLAARN +V+ L KI DFG++R++ T T+G +PVRW APE+
Sbjct: 1255 YLAAKKFVHRDLAARNCMVSDDLTVKIGDFGMTRDVYETDYYRKGTKG-LLPVRWMAPES 1313
Query: 758 IAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEAVYQ 817
+ FTS SDVWS G+V WE+++ +PY SN V++ + G + P +CP+ +Y
Sbjct: 1314 LKDGVFTSFSDVWSYGVVLWEMVTLASQPYQGLSNDQVLRYVIDGGVMERPENCPDILYG 1373
Query: 818 LMLDCWQKERTHRPTFSSIVKTL 840
+M W + T RPTF I + L
Sbjct: 1374 MMRQTWCHKATRRPTFIDIEREL 1396
>UniRef50_A6NNJ8 Cluster: Uncharacterized protein LTK; n=12;
Euarchontoglires|Rep: Uncharacterized protein LTK - Homo
sapiens (Human)
Length = 803
Score = 187 bits (456), Expect = 1e-45
Identities = 105/291 (36%), Positives = 158/291 (54%), Gaps = 16/291 (5%)
Query: 575 EIDASCITIEAIIGGGEFGDVCRGK-LKLPASCGPEIDVAIKTLKPGSTERARRDFLAEA 633
E+ + +T+ +G G FG+V G + LP P + VAIKTL + + DFL EA
Sbjct: 443 EVSPANVTLLRALGHGAFGEVYEGLVIGLPGDSSP-LQVAIKTLPELCSPQDELDFLMEA 501
Query: 634 SIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLR------ANDGKFRVLQLVG 687
I+ +F H N++ G+ + P +I+ E M G + +FLR + L+
Sbjct: 502 LIISKFRHQNIVRCVGLSLRATPRLILLELMSGGDMKSFLRHSRPHLGQPSPLVMRDLLQ 561
Query: 688 MLRGIATGMQYLSEMNYIHRDLAARNVLVNS---QLVCKIADFGLSREIESTADGAYTTR 744
+ + IA G YL E ++IHRD+AARN L++ V KI DFG++R+I + Y R
Sbjct: 562 LAQDIAQGCHYLEENHFIHRDIAARNCLLSCAGPSRVAKIGDFGMARDIYRAS---YYRR 618
Query: 745 GGK--IPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKG 802
G + +PV+W PEA FTS +D WS G++ WE+ S G PY +NQ+V+ + G
Sbjct: 619 GDRALLPVKWMPPEAFLEGIFTSKTDSWSFGVLLWEIFSLGYMPYPGRTNQEVLDFVVGG 678
Query: 803 YRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLIRCPDTLRKI 853
R+ P CP VY++M CWQ E RP+F+SI++ L + PD L +
Sbjct: 679 GRMDPPRGCPGPVYRIMTQCWQHEPELRPSFASILERLQYCTQDPDVLNSL 729
>UniRef50_P43405 Cluster: Tyrosine-protein kinase SYK; n=23;
Theria|Rep: Tyrosine-protein kinase SYK - Homo sapiens
(Human)
Length = 635
Score = 187 bits (456), Expect = 1e-45
Identities = 99/277 (35%), Positives = 160/277 (57%), Gaps = 8/277 (2%)
Query: 562 YEDPNQAVREFAREIDASCITIE-AIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPG 620
Y DP + +R +D +T+E +G G FG V +G ++ VA+K LK
Sbjct: 352 YADPEE-IRPKEVYLDRKLLTLEDKELGSGNFGTVKKGYYQMKKVVKT---VAVKILKNE 407
Query: 621 STERARRD-FLAEASIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRANDGK 679
+ + A +D LAEA++M Q ++P ++ + G+ + M++ E E G L+ +L+ N
Sbjct: 408 ANDPALKDELLAEANVMQQLDNPYIVRMIGIC-EAESWMLVMEMAELGPLNKYLQQNR-H 465
Query: 680 FRVLQLVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADG 739
+ ++ ++ ++ GM+YL E N++HRDLAARNVL+ +Q KI+DFGLS+ + + +
Sbjct: 466 VKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENY 525
Query: 740 AYTTRGGKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSI 799
GK PV+W APE I + KF+S SDVWS G++ WE S+G++PY +V +
Sbjct: 526 YKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAML 585
Query: 800 EKGYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSI 836
EKG R+ P CP +Y LM CW + +RP F+++
Sbjct: 586 EKGERMGCPAGCPREMYDLMNLCWTYDVENRPGFAAV 622
>UniRef50_A7SZN9 Cluster: Predicted protein; n=3; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 283
Score = 187 bits (455), Expect = 1e-45
Identities = 110/282 (39%), Positives = 158/282 (56%), Gaps = 16/282 (5%)
Query: 575 EIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEAS 634
+I + + +G GEFG V G + P G + A+K LK +TE +D L E
Sbjct: 1 QIPREAVELGRTLGEGEFGKVIEGNVTEPD--GTRVHCAVKKLKRTATESDWKDLLNELD 58
Query: 635 IMGQF-EHPNVIFLQGVVTKCN-PIMIITEFMENGSLDTFLRANDGKFR------VLQLV 686
IM Q EHPN++ L G + P+M+I EF NG+L +L+ N K VL +
Sbjct: 59 IMVQVGEHPNIVNLIGACSDPEGPLMVIVEFCGNGNLLHYLQKNSNKNYSNLHEYVLTIP 118
Query: 687 GMLR-----GIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAY 741
R +A+GM +L +M +HRDLAARNVL++ L K++DFGLSR+I + +
Sbjct: 119 ARERLRIAADVASGMAHLEKMRCVHRDLAARNVLLDEALTAKVSDFGLSRDIYTNSVYEK 178
Query: 742 TTRGGKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEK 801
TT GGK+P +W A E+I +TS SD WS G++ WE+ + G PY ++ Q+++ S++K
Sbjct: 179 TT-GGKLPAKWMAIESIEAGLYTSHSDAWSFGVLLWEIETGGCIPYPTFTVQEMLNSLKK 237
Query: 802 GYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKL 843
GYRL P C E +Y LML CW + RP F I L +L
Sbjct: 238 GYRLEKPPYCLEPLYTLMLSCWSADPALRPHFVEICARLKQL 279
>UniRef50_A7RNB1 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 280
Score = 187 bits (455), Expect = 1e-45
Identities = 106/283 (37%), Positives = 155/283 (54%), Gaps = 18/283 (6%)
Query: 575 EIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEAS 634
EI + ++ +G GEFG V G+L + + VAIK LK + +D L E
Sbjct: 2 EIPRDRVVLKDKLGEGEFGIVMEGELLIEEEAPRK--VAIKMLKSDADRTDHKDMLRELD 59
Query: 635 IM-GQFEHPNVIFLQGVVTKCNPIMIITEFMENGSL-----------DTFLRAN-DGKFR 681
+ G +H NV+ L G T P+ IITEF+ G+L +++ AN K
Sbjct: 60 MFKGIGQHENVVSLIGACTLGMPLYIITEFIAGGTLLELLRESRCITSSYVNANLVSKLS 119
Query: 682 VLQLVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAY 741
L+ + G A GM+++S ++HRDLA RNVLV L KI DFGLSR+I S DG Y
Sbjct: 120 GKDLLKLALGAARGMRHISGNRFVHRDLATRNVLVTEDLTAKITDFGLSRDIYS--DGIY 177
Query: 742 -TTRGGKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIE 800
+GGK+P++W APE++ +T+ SD+WS G++ WEV SFG PY +++ +
Sbjct: 178 LNAKGGKLPLKWMAPESLLDYVYTTQSDIWSFGVLMWEVWSFGAMPYSAVVPNELLSMLM 237
Query: 801 KGYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKL 843
G+RL P CPE +Y +M+ CW E RP+F+ + L+ L
Sbjct: 238 SGFRLSRPPLCPEEIYDVMMSCWNAEPEVRPSFAKLCTVLESL 280
>UniRef50_UPI0000DB7735 Cluster: PREDICTED: similar to Insulin
receptor precursor (IR); n=1; Apis mellifera|Rep:
PREDICTED: similar to Insulin receptor precursor (IR) -
Apis mellifera
Length = 1374
Score = 186 bits (454), Expect = 2e-45
Identities = 104/277 (37%), Positives = 151/277 (54%), Gaps = 14/277 (5%)
Query: 575 EIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEAS 634
EI + I +G G FG V G+ P + VA+KTLK GS+ + DFL+E
Sbjct: 936 EIPRHRVVINRKLGEGAFGTVYGGEAFFPEKGW--LAVAVKTLKIGSSTEEKLDFLSEVE 993
Query: 635 IMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRA-----NDGKFRVL------ 683
+M QFEH N+I L GV K P++ + EFM G L T+L A ND +
Sbjct: 994 VMKQFEHKNIIKLLGVCIKSEPVLTVMEFMLYGDLKTYLLARRHLVNDNSYEDSDEISNK 1053
Query: 684 QLVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTT 743
+L M +A + YL++ Y+HRD+A+RN LVN+Q V K+ DFG++R + D
Sbjct: 1054 KLTAMALDVARALSYLAQSKYVHRDIASRNCLVNAQRVVKLGDFGMTRLMYEN-DYYKFN 1112
Query: 744 RGGKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGY 803
R G +PVRW APE++ F+ ASDVWS G++ +E+++FG P+ SN +V+ ++ G
Sbjct: 1113 RRGMLPVRWMAPESLGLGIFSPASDVWSYGVLLYEIITFGSFPFQGMSNIEVLNHVKSGN 1172
Query: 804 RLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTL 840
L P + LM CW+ + RPT IV+ L
Sbjct: 1173 SLMVPKGVKIQLENLMYSCWRLDHIKRPTAPEIVEFL 1209
>UniRef50_Q7KJ08 Cluster: Receptor protein tyrosine kinase ALK splice
variant A; n=9; Diptera|Rep: Receptor protein tyrosine
kinase ALK splice variant A - Drosophila melanogaster
(Fruit fly)
Length = 1701
Score = 186 bits (454), Expect = 2e-45
Identities = 101/265 (38%), Positives = 146/265 (55%), Gaps = 14/265 (5%)
Query: 587 IGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEASIMGQFEHPNVIF 646
+G G FG+V + E+ VA+KTL+ DFL EA+IM +F HPN++
Sbjct: 1199 LGKGAFGEVYMALYRHRDGDAVEMGVAVKTLREDPKREKEEDFLKEAAIMAKFNHPNMVH 1258
Query: 647 LQGVVTKCNPIMIITEFMENGSLDTFLRANDGK------FRVLQLVGMLRGIATGMQYLS 700
L GV P I+ E + G L FLR N + L+ +A G +Y+
Sbjct: 1259 LIGVCFDRQPYYIVLELLAGGDLQKFLRENRNTPERPSLLTMKDLLFCALDVAKGCRYME 1318
Query: 701 EMNYIHRDLAARNVLVNSQ---LVCKIADFGLSREIESTADGAYTTRGGK--IPVRWTAP 755
+IHRD+AARN L++S+ V KIADFG+SR+I + Y +GGK +P++W P
Sbjct: 1319 SKRFIHRDIAARNCLLSSKGPGRVVKIADFGMSRDIYRSD---YYRKGGKAMLPIKWMPP 1375
Query: 756 EAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEAV 815
EA FTS +DVWS GI+ WEV S G PY N V++ + +G RL +P +CP ++
Sbjct: 1376 EAFLDGIFTSKTDVWSFGILLWEVFSLGRSPYPGQHNTQVMELVVRGGRLGSPTECPVSI 1435
Query: 816 YQLMLDCWQKERTHRPTFSSIVKTL 840
Y++M DCW RPTF ++++ L
Sbjct: 1436 YKVMADCWNPTPEDRPTFITLLEHL 1460
>UniRef50_UPI0000D57178 Cluster: PREDICTED: similar to CG14396-PA,
isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG14396-PA, isoform A - Tribolium castaneum
Length = 1065
Score = 186 bits (453), Expect = 2e-45
Identities = 111/299 (37%), Positives = 161/299 (53%), Gaps = 32/299 (10%)
Query: 575 EIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEID-VAIKTLKPGSTERARRDFLAEA 633
E + + IE +G GEFG V R K L S P + VA+KTLK + E D L+E
Sbjct: 737 EFPRNRLIIEQTLGEGEFGKVLRAKA-LNISGQPGLTTVAVKTLKDDARESELNDLLSEY 795
Query: 634 SIMGQFEHPNVIFLQGVVTKCN-PIMIITEFMENGSLDTFLRA----------------- 675
++ + HPNVI L GV T PI +I EF E+GSL +LR
Sbjct: 796 QLLKEVSHPNVIRLLGVCTAPGGPIYLIIEFAEHGSLRNYLRRSRHLKSECGRLPSSTVD 855
Query: 676 ---------NDGKFRVLQLVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIAD 726
N K +++ I GM YLSE+ +HRDLAARNVL+ + +CKI+D
Sbjct: 856 ENDVHYDEPNISKVTPKEILSFAWQICKGMAYLSEIKLVHRDLAARNVLLAADQICKISD 915
Query: 727 FGLSREIESTADGAYTTRG-GKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGER 785
FGL+R+I D AY R G++PV+W APE+++ +T+ SDVWS GI+ WE+++ G
Sbjct: 916 FGLTRDIYE--DDAYFKRSKGRVPVKWMAPESLSDHIYTNKSDVWSFGILVWELVTLGAT 973
Query: 786 PYWNWSNQDVIKSIEKGYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLI 844
PY + Q++ + +GYR+ P +C +Y +M CW + RPTF + +K++
Sbjct: 974 PYPGIAVQNLFHLLRQGYRMERPDNCSPTLYNIMRSCWHIDPEQRPTFQELAALWEKML 1032
>UniRef50_A7RGW8 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 337
Score = 186 bits (453), Expect = 2e-45
Identities = 105/294 (35%), Positives = 159/294 (54%), Gaps = 18/294 (6%)
Query: 575 EIDASCITIEAIIGGGEFGDVCRGKLK-LPASC-GPEIDVAIKTLKPGSTERARRDFLAE 632
E+D S I ++G G FG V + + LP E VA+K L +T RR+FL+E
Sbjct: 12 EVDYSSIAFGEVVGSGAFGKVTKATIVGLPGGPENKETVVAVKKLNAMATMEDRRNFLSE 71
Query: 633 ASIMGQF-EHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRANDGKF----------- 680
+M Q +H N++ + G VT + +ITE+ G L +LRA K
Sbjct: 72 IEMMKQLGKHLNIVSILGCVTHAGQLCLITEYCPYGDLRNYLRAIRDKVSTRDSLAGRAP 131
Query: 681 -RVL---QLVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIEST 736
R L L+ R IA GM+YLS+ ++HRDLAARN+L+ + KI+DFGL+R++ +
Sbjct: 132 GRELTQNDLLSFARQIAVGMEYLSQKMFVHRDLAARNILICEDNLVKISDFGLTRDVYES 191
Query: 737 ADGAYTTRGGKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVI 796
++ GK+P++W APEAI T+ SDVW+ G+V WE+++ G PY S ++
Sbjct: 192 SEYHKMHNTGKLPLKWMAPEAIFQNVHTTKSDVWAFGVVLWEIVTLGGSPYPGQSGKEFY 251
Query: 797 KSIEKGYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLIRCPDTL 850
K ++ GYR+ P C +Y +M CW RPTF+ + L++L+ D L
Sbjct: 252 KKLKNGYRMEKPDMCSPELYAMMRSCWASSPEDRPTFTKLRNQLEQLMDREDEL 305
>UniRef50_O76997 Cluster: Putative neurotrophin receptor LTRK 1
precursor; n=2; Lymnaea stagnalis|Rep: Putative
neurotrophin receptor LTRK 1 precursor - Lymnaea
stagnalis (Great pond snail)
Length = 794
Score = 186 bits (453), Expect = 2e-45
Identities = 102/278 (36%), Positives = 155/278 (55%), Gaps = 20/278 (7%)
Query: 581 ITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEASIMGQFE 640
I + +IG G FG V G VA+KTLK ++ +RDF EA ++ E
Sbjct: 504 ILLMRVIGEGAFGRVFLGTCAHLIQKNEFAIVAVKTLKGSCSDSLKRDFEREAEMLATIE 563
Query: 641 HPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLR----------------ANDGKFRVLQ 684
H N++ GV T+ + M+I EFMENG L+ +LR +++G+ Q
Sbjct: 564 HANIVTFYGVCTESDQWMMIFEFMENGDLNKYLRMHGPDAAFLKDRDSMDSDEGQLTREQ 623
Query: 685 LVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTR 744
L+ ++ IA+ M+YL+ +++HRDLA RN LV LV K+ DFG+SR++ +T Y
Sbjct: 624 LMKIVLQIASAMEYLALQHFVHRDLATRNCLVGCDLVVKLGDFGMSRDVYTT--DYYRVE 681
Query: 745 G-GKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGY 803
G +PVRW PE+I +R FT+ SDVWS G+ WEV ++G++P++ +SN +VI+ I+
Sbjct: 682 GTAMLPVRWMPPESIIYRTFTTESDVWSFGVTLWEVFTYGKQPWFEYSNSEVIEHIKNSR 741
Query: 804 RLP-APMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTL 840
L P C + VY++M CW+ R T I + L
Sbjct: 742 TLKRPPRTCTDGVYRVMQGCWKPNPQDRLTMKDIAELL 779
>UniRef50_Q13882 Cluster: Tyrosine-protein kinase 6; n=11;
Mammalia|Rep: Tyrosine-protein kinase 6 - Homo sapiens
(Human)
Length = 451
Score = 186 bits (453), Expect = 2e-45
Identities = 98/255 (38%), Positives = 147/255 (57%), Gaps = 11/255 (4%)
Query: 587 IGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEASIMGQFEHPNVIF 646
+G G FG+V G K + VAIK + + + +E M + H +++
Sbjct: 197 LGSGYFGEVFEGLWK------DRVQVAIKVISRDNLLHQQM-LQSEIQAMKKLRHKHILA 249
Query: 647 LQGVVTKCNPIMIITEFMENGSLDTFLRANDGK-FRVLQLVGMLRGIATGMQYLSEMNYI 705
L VV+ +P+ IITE M GSL LR +D K V +L+ + +A GM YL NYI
Sbjct: 250 LYAVVSVGDPVYIITELMAKGSLLELLRDSDEKVLPVSELLDIAWQVAEGMCYLESQNYI 309
Query: 706 HRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGGKIPVRWTAPEAIAFRKFTS 765
HRDLAARN+LV +CK+ DFGL+R I+ + Y + IP +WTAPEA++ +++
Sbjct: 310 HRDLAARNILVGENTLCKVGDFGLARLIK---EDVYLSHDHNIPYKWTAPEALSRGHYST 366
Query: 766 ASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEAVYQLMLDCWQK 825
SDVWS GI+ E+ S G+ PY SN + ++ GYR+P P++CP +V++LML CW +
Sbjct: 367 KSDVWSFGILLHEMFSRGQVPYPGMSNHEAFLRVDAGYRMPCPLECPPSVHKLMLTCWCR 426
Query: 826 ERTHRPTFSSIVKTL 840
+ RP F ++ + L
Sbjct: 427 DPEQRPCFKALRERL 441
>UniRef50_UPI0000E49FB6 Cluster: PREDICTED: similar to RE05926p,
partial; n=2; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to RE05926p, partial -
Strongylocentrotus purpuratus
Length = 859
Score = 186 bits (452), Expect = 3e-45
Identities = 104/288 (36%), Positives = 158/288 (54%), Gaps = 21/288 (7%)
Query: 575 EIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEAS 634
E + +T+ +G G F DV + + + + VA+K LK +TE + D E S
Sbjct: 307 EFPRNRLTLFNKLGSGSFADVYKAEAVGIITKEEKTIVAVKRLKETATENDKSDLSKELS 366
Query: 635 IMGQFE-HPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRA------------NDGKFR 681
+ + HPN++ + G T +P II E++ N +L +LR N K +
Sbjct: 367 LYMYLDPHPNIVNILGCCTDSDPWYIIMEYLPNNNLQGYLRQIRTGESMTADYRNVKKQK 426
Query: 682 VLQLVGMLR---GIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTAD 738
+ +L IA GM+YL+ IHRDLAARN+L+ VCK++DFGL+R++E D
Sbjct: 427 DIPPNDLLTFGVQIARGMEYLASRQCIHRDLAARNILLGEGYVCKVSDFGLARDLE---D 483
Query: 739 G-AYTTRG-GKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVI 796
G Y + G++PVRW +PE++ +TS SDVWS I+ WE+++ G PY S++ V+
Sbjct: 484 GQTYEMKSQGRVPVRWMSPESLLHNTYTSQSDVWSFAILIWEIVTLGSHPYPGMSSKQVV 543
Query: 797 KSIEKGYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLI 844
K I GYRLP P C + +Y LM +CW E RPTFS + L+ ++
Sbjct: 544 KEISAGYRLPKPEHCSQDIYNLMKECWAYEAEERPTFSQVKVRLENML 591
Score = 35.5 bits (78), Expect = 6.8
Identities = 23/83 (27%), Positives = 39/83 (46%), Gaps = 1/83 (1%)
Query: 571 EFAREIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFL 630
E E + +T+ +G G F DV + + + + VA+K LK +TE + D
Sbjct: 128 ETKMEFPRNRLTLLNKLGSGSFADVYKAEALGIITKEQKTIVAVKRLKDTATENDKSDLS 187
Query: 631 AEASIMGQFE-HPNVIFLQGVVT 652
E S+ + HPN++ + G T
Sbjct: 188 KELSLYMYLDPHPNIVNILGCCT 210
>UniRef50_P42687 Cluster: Tyrosine-protein kinase SPK-1; n=1;
Girardia tigrina|Rep: Tyrosine-protein kinase SPK-1 -
Dugesia tigrina (Planarian)
Length = 497
Score = 186 bits (452), Expect = 3e-45
Identities = 110/279 (39%), Positives = 159/279 (56%), Gaps = 18/279 (6%)
Query: 575 EIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEAS 634
EI+ I I IG G FG V R K G +VA K L+ ER + F+ EA
Sbjct: 214 EINRENIEILNEIGRGFFGSVHRAKW------GRSYEVAAKMLQSSKAEREK--FVLEAK 265
Query: 635 IMGQFEHPNVIFLQGVVTKCN--PIMIITEFMENGSLDTFLRANDGKFRVL-QLVGMLRG 691
IM + H ++ L GV T+ P++II E+M+NGSL +L+ DGK L Q+V M+
Sbjct: 266 IMHKLRHRKIVELLGVCTEPQDMPMLIIVEYMKNGSLKEYLKTPDGKKTNLNQMVHMMAE 325
Query: 692 IATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGGKIPVR 751
I+ GM YL +HRDL A N+LV + L K+ADFGL+ E+ + G + + P +
Sbjct: 326 ISEGMAYLESEKVVHRDLRADNILVANDLTRKVADFGLT-ELTDGSLGDQEKKTLRFPYK 384
Query: 752 WTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAP--- 808
WTAPEA + FTS SDVWS GIV +E++++ PY + ++VI+ + KGYR+P P
Sbjct: 385 WTAPEAAKSKVFTSKSDVWSYGIVMFEILTWASSPYPDIPAKEVIEKVSKGYRMPNPEKF 444
Query: 809 ---MDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLI 844
+ CP+ +Y++M+ CW RPTF + + +D LI
Sbjct: 445 ITGVCCPDEIYKIMIWCWDANPEKRPTFLVLQEKMDLLI 483
>UniRef50_O15146 Cluster: Muscle, skeletal receptor tyrosine protein
kinase precursor; n=53; Euteleostomi|Rep: Muscle,
skeletal receptor tyrosine protein kinase precursor -
Homo sapiens (Human)
Length = 869
Score = 185 bits (451), Expect = 4e-45
Identities = 103/280 (36%), Positives = 155/280 (55%), Gaps = 24/280 (8%)
Query: 587 IGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEASIMGQFEHPNVIF 646
IG G FG V + + P VA+K LK ++ + DF EA++M +F++PN++
Sbjct: 581 IGEGAFGRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVK 640
Query: 647 LQGVVTKCNPIMIITEFMENGSLDTFLRA-----------NDGKFRV------------L 683
L GV P+ ++ E+M G L+ FLR+ +D R
Sbjct: 641 LLGVCAVGKPMCLLFEYMAYGDLNEFLRSMSPHTVCSLSHSDLSMRAQVSSPGPPPLSCA 700
Query: 684 QLVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTT 743
+ + + R +A GM YLSE ++HRDLA RN LV +V KIADFGLSR I S AD
Sbjct: 701 EQLCIARQVAAGMAYLSERKFVHRDLATRNCLVGENMVVKIADFGLSRNIYS-ADYYKAN 759
Query: 744 RGGKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGY 803
IP+RW PE+I + ++T+ SDVW+ G+V WE+ S+G +PY+ ++++VI + G
Sbjct: 760 ENDAIPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYVRDGN 819
Query: 804 RLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKL 843
L P +CP +Y LM CW K RP+F+SI + L+++
Sbjct: 820 ILSCPENCPVELYNLMRLCWSKLPADRPSFTSIHRILERM 859
>UniRef50_Q9YI66 Cluster: Developmental receptor tyrosine kinase;
n=6; Bilateria|Rep: Developmental receptor tyrosine
kinase - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 874
Score = 185 bits (450), Expect = 6e-45
Identities = 111/277 (40%), Positives = 156/277 (56%), Gaps = 19/277 (6%)
Query: 581 ITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERAR-RDFLAEASIMGQF 639
+T+ ++G GEFG V LK + G + VA+K LK + L EA+ M F
Sbjct: 497 LTLGRMLGKGEFGSVREAFLKSENNSGQK--VAVKVLKTDINSSSDIEQCLKEAAYMKDF 554
Query: 640 EHPNVIFLQGV-----VTKCNPI-MIITEFMENGSLDTFL---RANDGKFRVLQ--LVGM 688
HPNVI L GV + PI M+I FM++G L TFL R D F V Q L+
Sbjct: 555 HHPNVIQLIGVSLHRRAQQRLPIPMVILPFMKHGDLHTFLLMSRLGDEPFTVSQQILIQF 614
Query: 689 LRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGG-- 746
+ IA GM+YLS N IHRDLAARN ++N + +ADFGLS++I S G Y +G
Sbjct: 615 MLDIARGMEYLSNKNIIHRDLAARNCMLNENMSVCVADFGLSKKIYS---GDYYRQGSVS 671
Query: 747 KIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLP 806
K+PV+W A E++A +T+ SDVW+ G+ WE+M+ G+ PY N ++ + + KG RL
Sbjct: 672 KLPVKWIALESLADNVYTTQSDVWAFGVTMWEIMTRGQTPYPGVENSEIYEYLIKGERLK 731
Query: 807 APMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKL 843
P DCP +Y++M CW RP+F ++ L+ L
Sbjct: 732 QPPDCPADIYEIMHSCWSPVPKCRPSFQHLIDQLELL 768
>UniRef50_P04412 Cluster: Epidermal growth factor receptor precursor;
n=129; Endopterygota|Rep: Epidermal growth factor
receptor precursor - Drosophila melanogaster (Fruit fly)
Length = 1426
Score = 185 bits (450), Expect = 6e-45
Identities = 101/262 (38%), Positives = 145/262 (55%), Gaps = 3/262 (1%)
Query: 586 IIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEASIMGQFEHPNVI 645
++G G FG V +G + +P +I VAIK L + + +FL EA IM EH N++
Sbjct: 943 VLGMGAFGRVYKG-VWVPEGENVKIPVAIKELLKSTGAESSEEFLREAYIMASEEHVNLL 1001
Query: 646 FLQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFRVLQLVGMLRGIATGMQYLSEMNYI 705
L V + +M+IT+ M G L ++R N K L+ IA GM YL E +
Sbjct: 1002 KLLAVCMS-SQMMLITQLMPLGCLLDYVRNNRDKIGSKALLNWSTQIAKGMSYLEEKRLV 1060
Query: 706 HRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGGKIPVRWTAPEAIAFRKFTS 765
HRDLAARNVLV + + KI DFGL++ + S ++ Y GGK+P++W A E I R FTS
Sbjct: 1061 HRDLAARNVLVQTPSLVKITDFGLAKLLSSDSN-EYKAAGGKMPIKWLALECIRNRVFTS 1119
Query: 766 ASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEAVYQLMLDCWQK 825
SDVW+ G+ WE+++FG+RP+ N +D+ IE G +L P C +Y +L CW
Sbjct: 1120 KSDVWAFGVTIWELLTFGQRPHENIPAKDIPDLIEVGLKLEQPEICSLDIYCTLLSCWHL 1179
Query: 826 ERTHRPTFSSIVKTLDKLIRCP 847
+ RPTF + + R P
Sbjct: 1180 DAAMRPTFKQLTTVFAEFARDP 1201
>UniRef50_UPI0000E47068 Cluster: PREDICTED: similar to tyrosine
protein kinase; n=2; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to tyrosine protein kinase -
Strongylocentrotus purpuratus
Length = 1566
Score = 184 bits (449), Expect = 8e-45
Identities = 104/274 (37%), Positives = 153/274 (55%), Gaps = 15/274 (5%)
Query: 575 EIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEAS 634
E+ + + +G G FG V G+ L + VA+KTLK G++ + DFL+EA
Sbjct: 1014 EMPRENVVLNRKLGEGAFGTVYGGEALLDDNKWAA--VAVKTLKLGASVEEKLDFLSEAE 1071
Query: 635 IMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFL-----RANDGKF----RVL-- 683
+M +F H N++ L GV T+ P+ + EFM G L TFL +G + V+
Sbjct: 1072 VMKRFNHKNIVNLLGVCTRGEPMYAVMEFMLYGDLKTFLLGRRHLVGEGVYERNQHVMCP 1131
Query: 684 -QLVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYT 742
QL M+ IA+G+ YL+ +NY+HRDLA RN LV++ KI DFG++R + +D
Sbjct: 1132 DQLTSMVSDIASGLSYLASINYVHRDLACRNCLVDASYTVKIGDFGMTRALYD-SDYYRL 1190
Query: 743 TRGGKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKG 802
+ K+PVRW APE++ FT+ SDVWS+G+V +EV++FG PY SN +V+ I
Sbjct: 1191 GKRSKLPVRWMAPESLTEGIFTTMSDVWSLGVVIYEVVTFGSFPYQELSNAEVLDYIRNR 1250
Query: 803 YRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSI 836
L P C A+ LM+ CW + HRPT +
Sbjct: 1251 NSLRPPEGCSPALGALMMQCWAIQPQHRPTAKDV 1284
>UniRef50_Q9YGM5 Cluster: Plasminogen related growth factor receptor
2; n=11; Clupeocephala|Rep: Plasminogen related growth
factor receptor 2 - Fugu rubripes (Japanese pufferfish)
(Takifugu rubripes)
Length = 1375
Score = 184 bits (449), Expect = 8e-45
Identities = 98/275 (35%), Positives = 154/275 (56%), Gaps = 6/275 (2%)
Query: 576 IDASCITIE--AIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEA 633
I A + IE +IG G FG V G L S E A+K+L + + FL E
Sbjct: 1058 IPADMLRIEDRQVIGKGHFGTVYHGYLI--DSNKQETHCAVKSLNRITDLKDVDHFLREG 1115
Query: 634 SIMGQFEHPNVIFLQGVVTKCNPI-MIITEFMENGSLDTFLRANDGKFRVLQLVGMLRGI 692
IM F+HPN++ L G++ + +++ +M++G + F+R+ V L+G +
Sbjct: 1116 LIMKGFDHPNILSLLGIMLPKEGLPLVVLPYMKHGDVRHFIRSEKRNPTVKDLIGFGLQV 1175
Query: 693 ATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREI-ESTADGAYTTRGGKIPVR 751
A GM+YL++ ++HRDLAARN +++ K+ADFG++R+I + + K+PV+
Sbjct: 1176 AKGMEYLAQKKFVHRDLAARNCMLDETYTVKVADFGMARDIYDKEYYSIQDHKQVKLPVK 1235
Query: 752 WTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDC 811
W A E++ +KFTS SDVWS GI+ WE+++ G PY + D+ + KG RLP P C
Sbjct: 1236 WMAIESLQTQKFTSKSDVWSYGILMWELLTRGASPYPDVDPYDITNYLLKGRRLPQPQFC 1295
Query: 812 PEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLIRC 846
P +Y +ML CW E RP+FSS+ + ++ C
Sbjct: 1296 PNTLYSIMLSCWDPEPDFRPSFSSLASDVQHILLC 1330
>UniRef50_Q9U5A8 Cluster: Insulin receptor-like protein precursor;
n=1; Bombyx mori|Rep: Insulin receptor-like protein
precursor - Bombyx mori (Silk moth)
Length = 1472
Score = 184 bits (449), Expect = 8e-45
Identities = 103/266 (38%), Positives = 151/266 (56%), Gaps = 13/266 (4%)
Query: 587 IGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEASIMGQFEHPNVIF 646
+G G FG V G K PE AIKT+ +T+R R +FL EAS+M F+ +V+
Sbjct: 1088 LGQGSFGMVYEGIAKEIVKGKPETRCAIKTVNEHATDRERIEFLNEASVMKAFDTFHVVR 1147
Query: 647 LQGVVTKCNPIMIITEFMENGSLDTFLRAN----DGKFR-------VLQ-LVGMLRGIAT 694
L GVV++ P +++ E ME G L T+LR+ +G LQ ++ M IA
Sbjct: 1148 LLGVVSRGQPTLVVMELMERGDLKTYLRSMRPDAEGSLPSSPPVPPTLQNILQMAIEIAD 1207
Query: 695 GMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGGKIPVRWTA 754
GM YLS ++HRDLAARN +V L K+ DFG++R+I T T+G +PVRW +
Sbjct: 1208 GMAYLSAKKFVHRDLAARNCMVAGDLTVKVGDFGMTRDIYETDYYRKGTKG-LMPVRWMS 1266
Query: 755 PEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEA 814
PE++ F+S+SD WS G+V WE+ + +PY SN+ V++ + +G + P CP+
Sbjct: 1267 PESLKDGVFSSSSDAWSYGVVLWEMATLAMQPYQGLSNEQVLRYVVEGGVMERPEQCPDR 1326
Query: 815 VYQLMLDCWQKERTHRPTFSSIVKTL 840
+Y+LM CW + RPTF +V L
Sbjct: 1327 LYELMRACWTHRPSARPTFLQLVADL 1352
>UniRef50_UPI0000D57699 Cluster: PREDICTED: similar to CG18247-PA;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG18247-PA - Tribolium castaneum
Length = 725
Score = 184 bits (447), Expect = 1e-44
Identities = 99/254 (38%), Positives = 144/254 (56%), Gaps = 5/254 (1%)
Query: 586 IIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEASIMGQFEHPNVI 645
+IG GEFG V G G EI VAIKT++ E + L EA +M + H V+
Sbjct: 455 VIGEGEFGSVYEGTYT--KRNGEEIKVAIKTVRHEQIETSNA-ILKEAHVMMRLNHHCVV 511
Query: 646 FLQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFRVLQLVGMLRG-IATGMQYLSEMNY 704
L G+ +K P++++ E + GS+ ++ N + IA GM YL E +
Sbjct: 512 KLIGL-SKGRPLLMVQELVALGSMLNYIILNKESINPNSEFKIWAAQIACGMNYLEEQRF 570
Query: 705 IHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGGKIPVRWTAPEAIAFRKFT 764
IHRDLAARN+L+ SQ KI+DFGLSR + + + +GGK P++W APE+ + +F+
Sbjct: 571 IHRDLAARNILLASQHQAKISDFGLSRALAADHEYYRALQGGKWPLKWYAPESYNYGQFS 630
Query: 765 SASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEAVYQLMLDCWQ 824
SDVWS G+ WE+ SFG+ PY D IK IE G RL P CP+ +Y++M CW+
Sbjct: 631 HKSDVWSFGVAIWEMYSFGDVPYGELKGSDAIKIIEDGERLKQPDACPDHIYEIMRRCWE 690
Query: 825 KERTHRPTFSSIVK 838
+ +RPTF +++
Sbjct: 691 YDAENRPTFKELLE 704
>UniRef50_UPI0000D57494 Cluster: PREDICTED: similar to insulin
receptor; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to insulin receptor - Tribolium castaneum
Length = 1351
Score = 184 bits (447), Expect = 1e-44
Identities = 105/278 (37%), Positives = 152/278 (54%), Gaps = 14/278 (5%)
Query: 575 EIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEAS 634
E+ I + +G G FG V G + +I A+KT+ +T R R +FL EAS
Sbjct: 974 EVPRKKIELIRELGQGSFGMVYEG-IAQDVRGKAQIKCAVKTVNEHATNRERLEFLNEAS 1032
Query: 635 IMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFRVL----------- 683
+M F+ +V+ L GVV++ P ++I E M NG L T+LR++ V
Sbjct: 1033 VMKAFDTAHVVRLLGVVSQGQPTLVIMELMANGDLKTYLRSHRPDAEVYDPATAKQPPTL 1092
Query: 684 -QLVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYT 742
Q++ M IA GM YLS ++HRDLAARN +V L KI DFG++R+I T
Sbjct: 1093 KQILQMAIEIADGMAYLSAKKFVHRDLAARNCMVAEDLTVKIGDFGMTRDIYETDYYRKG 1152
Query: 743 TRGGKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKG 802
T+G +PVRW APE++ FTS SDVWS G+V WE+ + +PY SN V++ + G
Sbjct: 1153 TKG-LLPVRWMAPESLKDGVFTSNSDVWSYGVVLWEMATLASQPYQGLSNDQVLRYVIDG 1211
Query: 803 YRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTL 840
+ P +CP+ +Y LM CWQ + + RP+F + L
Sbjct: 1212 GVMERPENCPDKLYTLMRYCWQHKPSARPSFLKLCSLL 1249
>UniRef50_Q07912 Cluster: Activated CDC42 kinase 1; n=24;
Euteleostomi|Rep: Activated CDC42 kinase 1 - Homo
sapiens (Human)
Length = 1036
Score = 184 bits (447), Expect = 1e-44
Identities = 105/287 (36%), Positives = 151/287 (52%), Gaps = 8/287 (2%)
Query: 587 IGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPG--STERARRDFLAEASIMGQFEHPNV 644
+G G FG V RG+ P+ G + VA+K LKP S A DF+ E + M +H N+
Sbjct: 132 LGDGSFGVVRRGEWDAPS--GKTVSVAVKCLKPDVLSQPEAMDDFIREVNAMHSLDHRNL 189
Query: 645 IFLQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFRVLQLVGMLRGIATGMQYLSEMNY 704
I L GVV P+ ++TE GSL LR + G F + L +A GM YL +
Sbjct: 190 IRLYGVVLT-PPMKMVTELAPLGSLLDRLRKHQGHFLLGTLSRYAVQVAEGMGYLESKRF 248
Query: 705 IHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGGKIPVRWTAPEAIAFRKFT 764
IHRDLAARN+L+ ++ + KI DFGL R + D K+P W APE++ R F+
Sbjct: 249 IHRDLAARNLLLATRDLVKIGDFGLMRALPQNDDHYVMQEHRKVPFAWCAPESLKTRTFS 308
Query: 765 SASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEK-GYRLPAPMDCPEAVYQLMLDCW 823
ASD W G+ WE+ ++G+ P+ + ++ I+K G RLP P DCP+ +Y +M+ CW
Sbjct: 309 HASDTWMFGVTLWEMFTYGQEPWIGLNGSQILHKIDKEGERLPRPEDCPQDIYNVMVQCW 368
Query: 824 QKERTHRPTFSSIVKTLDKLIRCPDTLRKIAQNRSADPLAGDTPDLI 870
+ RPTF ++ L L P +R + D L D+I
Sbjct: 369 AHKPEDRPTFVALRDFL--LEAQPTDMRALQDFEEPDKLHIQMNDVI 413
>UniRef50_O02742 Cluster: Activated CDC42 kinase 2; n=13;
Euteleostomi|Rep: Activated CDC42 kinase 2 - Bos taurus
(Bovine)
Length = 747
Score = 183 bits (446), Expect = 2e-44
Identities = 105/287 (36%), Positives = 151/287 (52%), Gaps = 8/287 (2%)
Query: 587 IGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPG--STERARRDFLAEASIMGQFEHPNV 644
+G G FG V RG+ P+ G + VA+K LKP S A DF+ E + M +H N+
Sbjct: 132 LGDGSFGVVRRGEWDAPS--GKTVSVAVKCLKPDVLSQPEAMDDFIREVNAMHSLDHRNL 189
Query: 645 IFLQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFRVLQLVGMLRGIATGMQYLSEMNY 704
I L GVV P+ ++TE GSL LR + G F + L +A GM YL +
Sbjct: 190 IRLYGVVLT-PPMKMVTELAPLGSLLDRLRKHQGHFLLGTLSRYAVQVAEGMGYLEAKRF 248
Query: 705 IHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGGKIPVRWTAPEAIAFRKFT 764
IHRDLAARN+L+ ++ + KI DFGL R + D K+P W APE++ R F+
Sbjct: 249 IHRDLAARNLLLATRDLVKIGDFGLMRALPQNDDHYVMQEHRKVPFAWCAPESLKTRTFS 308
Query: 765 SASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEK-GYRLPAPMDCPEAVYQLMLDCW 823
ASD W G+ WE+ ++G+ P+ + ++ I+K G RLP P DCP+ +Y +M+ CW
Sbjct: 309 HASDTWMFGVTLWEMFTYGQEPWIGLNGSQILHKIDKEGERLPRPEDCPQDIYNVMVQCW 368
Query: 824 QKERTHRPTFSSIVKTLDKLIRCPDTLRKIAQNRSADPLAGDTPDLI 870
+ RPTF ++ L L P +R + D L D+I
Sbjct: 369 AHKPEDRPTFVALRDFL--LEAQPTDMRALQDFEEPDKLHIQMNDVI 413
>UniRef50_Q24145 Cluster: Tyrosine-protein kinase shark; n=2;
Sophophora|Rep: Tyrosine-protein kinase shark -
Drosophila melanogaster (Fruit fly)
Length = 939
Score = 183 bits (445), Expect = 2e-44
Identities = 98/261 (37%), Positives = 147/261 (56%), Gaps = 6/261 (2%)
Query: 576 IDASCITIEAIIGGGEFGDVCRGKLKLPASCGPE--IDVAIKTLKPGSTERARRDFLAEA 633
I+ + ++ IG GEFG V G L + G E ++VAIK L + + ++FL EA
Sbjct: 657 IEPEKLVLDREIGHGEFGSVHSGWLLRKSGAGEESRLEVAIKMLSDEHSNK--QEFLREA 714
Query: 634 SIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFRV-LQLVGMLRGI 692
S+M + EH ++ L G+ K +M++ E GS+ ++ + + +L I
Sbjct: 715 SVMMRLEHKCIVRLIGIA-KGEMLMMVQELAPLGSMLQYILDHGHEITANAELKVWASQI 773
Query: 693 ATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGGKIPVRW 752
A GM YL +++HRDLAARN+L+ ++ KI+DFG+SR + + T+GG+ P+RW
Sbjct: 774 ACGMHYLESQHFVHRDLAARNILLTARHQAKISDFGMSRSLRPGSTEYQFTQGGRWPIRW 833
Query: 753 TAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCP 812
APE+ F+ ASDVWS G+ WE+ S G PY SN D IK ++ G RLP P CP
Sbjct: 834 YAPESFNLGIFSHASDVWSFGVTIWEMFSLGAPPYGEISNVDAIKLVDSGERLPQPNLCP 893
Query: 813 EAVYQLMLDCWQKERTHRPTF 833
+Y +M CW++ RPTF
Sbjct: 894 AYIYAVMQSCWKERPKDRPTF 914
>UniRef50_P08581 Cluster: Hepatocyte growth factor receptor precursor;
n=81; Tetrapoda|Rep: Hepatocyte growth factor receptor
precursor - Homo sapiens (Human)
Length = 1390
Score = 183 bits (445), Expect = 2e-44
Identities = 96/279 (34%), Positives = 154/279 (55%), Gaps = 4/279 (1%)
Query: 567 QAVREFAREIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERAR 626
QAV+ + + +IG G FG V G L + G +I A+K+L +
Sbjct: 1064 QAVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLL--DNDGKKIHCAVKSLNRITDIGEV 1121
Query: 627 RDFLAEASIMGQFEHPNVIFLQGVVTKCNPI-MIITEFMENGSLDTFLRANDGKFRVLQL 685
FL E IM F HPNV+ L G+ + +++ +M++G L F+R V L
Sbjct: 1122 SQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDL 1181
Query: 686 VGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREI-ESTADGAYTTR 744
+G +A GM+YL+ ++HRDLAARN +++ + K+ADFGL+R++ + +
Sbjct: 1182 IGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKT 1241
Query: 745 GGKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYR 804
G K+PV+W A E++ +KFT+ SDVWS G+V WE+M+ G PY + + D+ + +G R
Sbjct: 1242 GAKLPVKWMALESLQTQKFTTKSDVWSFGVVLWELMTRGAPPYPDVNTFDITVYLLQGRR 1301
Query: 805 LPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKL 843
L P CP+ +Y++ML CW + RP+FS +V + +
Sbjct: 1302 LLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAI 1340
>UniRef50_Q86PM4 Cluster: Fibroblast growth factor receptor
precursor; n=1; Hydra vulgaris|Rep: Fibroblast growth
factor receptor precursor - Hydra attenuata (Hydra)
(Hydra vulgaris)
Length = 816
Score = 183 bits (445), Expect = 2e-44
Identities = 98/284 (34%), Positives = 163/284 (57%), Gaps = 14/284 (4%)
Query: 573 AREIDASCITIEAIIGGGEFGDVCRGKLK-LPASCGPEIDVAIKTLKPGSTERARRDFLA 631
A EI + + ++G G FG V R + LP G + VA+K LK E+ +DF++
Sbjct: 466 AWEIKLEQLETDCLLGEGAFGRVFRATARDLPNHTGVQT-VAVKMLKEDCCEQDLKDFIS 524
Query: 632 EASIMGQF-EHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRAN----------DGKF 680
E +M +H N++ L V ++ + I+ E+ +G+L +FL+ N K
Sbjct: 525 EIEVMKSIGKHINILNLLAVSSQQGKLYIVVEYCRHGNLRSFLKDNRPVMQANSVITKKI 584
Query: 681 RVLQLVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGA 740
+ L +A GM +L+ IHRD+AARNVLV + KIADFGL+R+I D
Sbjct: 585 TLYDLTSFCLQVARGMNFLASKKCIHRDIAARNVLVGEGYLMKIADFGLARDIHEQ-DYY 643
Query: 741 YTTRGGKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIE 800
G++PV+W A EA+ R +T+ SD+WS GI+ WE+++FG PY + + + ++
Sbjct: 644 RKCTDGRLPVKWMAIEALFDRVYTTQSDIWSFGILAWEIVTFGGSPYPGIALEKLFDLLK 703
Query: 801 KGYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLI 844
+GYR+ P++C + +Y LML+CW++ + RPTFS +++ L++++
Sbjct: 704 QGYRMERPLNCTDDMYTLMLNCWKEIPSKRPTFSQLIEDLERML 747
>UniRef50_UPI000051AB92 Cluster: PREDICTED: similar to Fak-like
tyrosine kinase CG3969-PA, isoform A; n=1; Apis
mellifera|Rep: PREDICTED: similar to Fak-like tyrosine
kinase CG3969-PA, isoform A - Apis mellifera
Length = 1270
Score = 182 bits (444), Expect = 3e-44
Identities = 117/326 (35%), Positives = 168/326 (51%), Gaps = 12/326 (3%)
Query: 551 TGSRTYIDPHTYEDPNQAVREFAREIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEI 610
TG+ T + + P V I A I + +G GEFG V +G + + G I
Sbjct: 87 TGALTMLPEERQDRPPIRVPN-KHMIPADAIIVNKELGTGEFGVVQQG---VWTNDGERI 142
Query: 611 DVAIKTLKPGSTERARRDFLAEASIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLD 670
VAIK L + +FL EA+IM +H +++ L GVV N +M++TE SL
Sbjct: 143 QVAIKCLSRERMQNNPIEFLKEAAIMYAIDHEHIVRLYGVVLDTNSLMLVTELAPLRSLL 202
Query: 671 TFLRAND--GKFRVLQLVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFG 728
L+ F VL L IA GMQYL IHRDLAARN+LV S+ KI+DFG
Sbjct: 203 ECLKEPSLRSSFPVLSLCDFSVQIADGMQYLEAKRLIHRDLAARNILVFSKNKVKISDFG 262
Query: 729 LSREIESTADGAYTTRGG--KIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERP 786
LSR + D T K+P+ W APE I++ KFTSASDVW+ G+ WE+ S+G +P
Sbjct: 263 LSRALGVGKDYYQTNFNVNLKLPIAWCAPECISYLKFTSASDVWAYGVTLWEMFSYGFQP 322
Query: 787 YWNWSNQDVIKSIE--KGYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLI 844
+ + ++++I+ RL P CP+ + LM CWQ E + RP FS ++ L L
Sbjct: 323 WAALTGHQILEAIDDPNFQRLEQPECCPKEYFSLMQQCWQHEPSKRPKFSELINLLPDL- 381
Query: 845 RCPDTLRKIAQNRSADPLAGDTPDLI 870
P+ ++ + + + L D+I
Sbjct: 382 -KPEQVQAVQDSMETNQLVYRQGDVI 406
>UniRef50_O97191 Cluster: Tyrosine-protein kinase receptor; n=1;
Geodia cydonium|Rep: Tyrosine-protein kinase receptor -
Geodia cydonium (Sponge)
Length = 570
Score = 182 bits (444), Expect = 3e-44
Identities = 109/275 (39%), Positives = 154/275 (56%), Gaps = 22/275 (8%)
Query: 587 IGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEASIMGQFEHPNVIF 646
+G G FG V +G +K ++VAIKTLK S + +F+ E+ +M F HPNV+
Sbjct: 275 LGEGAFGRVYKGSMKTGDDDDRTVEVAIKTLKDISQQENIDNFVQESILMLGFNHPNVLE 334
Query: 647 LQGV---VTKCNPIMIITEFMENGSLDTFLRAN-----DGKFRVL-------QLVGMLRG 691
L GV T +P +I+ FM NG L ++L + KF + + M
Sbjct: 335 LLGVCFDTTDRHP-LIVLPFMANGDLRSYLMSKRDPSVTTKFTHFPQGLDEERALVMCLE 393
Query: 692 IATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGGK--IP 749
+A GM+YLS +++HRDLAARN +V+ +L ++ADFGLSR++ S Y G K +P
Sbjct: 394 VARGMEYLSNSSFVHRDLAARNCMVSGELTVRVADFGLSRDVYSK---DYYRMGTKTMLP 450
Query: 750 VRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPM 809
V+W APE++A FT SDVWS G+VCWEV S PY N ++ I G RL P
Sbjct: 451 VKWMAPESLADNIFTVKSDVWSFGVVCWEVFSL-VAPYPGIGNHEMSDYIGGGRRLKIPR 509
Query: 810 DCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLI 844
CP +Y+LM CW +E RP FS +V L+++I
Sbjct: 510 LCPREIYELMEQCWNEESNKRPNFSELVSQLERVI 544
>UniRef50_P23049 Cluster: Tyrosine-protein kinase transforming
protein SEA; n=6; root|Rep: Tyrosine-protein kinase
transforming protein SEA - Avian erythroblastosis virus
(strain S13)
Length = 370
Score = 182 bits (444), Expect = 3e-44
Identities = 93/261 (35%), Positives = 149/261 (57%), Gaps = 4/261 (1%)
Query: 586 IIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEASIMGQFEHPNVI 645
+IG G FG V G P + A+K+L + +FL E +M F HP V+
Sbjct: 65 VIGRGHFGSVYHGTYMDPLL--GNLHCAVKSLHRITYLEEVEEFLREGILMKGFHHPQVL 122
Query: 646 FLQGVVTKCNPI-MIITEFMENGSLDTFLRANDGKFRVLQLVGMLRGIATGMQYLSEMNY 704
L GV + + +++ +M +G L F+RA + V +L+G +A GM+YL++ +
Sbjct: 123 SLLGVCLPRHGLPLVVLPYMRHGDLRHFVRAQERSPTVKELIGFGLQVALGMEYLAQKKF 182
Query: 705 IHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTT-RGGKIPVRWTAPEAIAFRKF 763
+HRDLAARN +++ L K+ADFGL+R++ + R K+PVRW A E++ +KF
Sbjct: 183 VHRDLAARNCMLDETLTVKVADFGLARDVFGKEYYSIRQHRHAKLPVRWMALESLQTQKF 242
Query: 764 TSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEAVYQLMLDCW 823
T+ SDVWS G++ WE+++ G PY D+ + + +G RLP P CP+ +Y +ML CW
Sbjct: 243 TTKSDVWSFGVLMWELLTRGASPYPEVDPYDMARYLLRGRRLPQPQPCPDTLYGVMLSCW 302
Query: 824 QKERTHRPTFSSIVKTLDKLI 844
RP+FS +V L++++
Sbjct: 303 APTPEERPSFSGLVCELERVL 323
>UniRef50_A7RL50 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 438
Score = 182 bits (443), Expect = 4e-44
Identities = 114/315 (36%), Positives = 169/315 (53%), Gaps = 18/315 (5%)
Query: 576 IDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTE---RARRDFLAE 632
I S + + +IG G FG V +G+ G ++DVA+K LK + + + DF+ E
Sbjct: 111 ITESSLVLYEMIGDGAFGYVRKGQWT--TDTGTKVDVAVKCLKFSADAAFIQMQTDFIKE 168
Query: 633 ASIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFRVLQLVGMLRGI 692
A+ M +HP++I L G+V P+M++TE G L T LR N +F V L + +
Sbjct: 169 ANSMALLDHPHIIRLFGIVLS-TPMMLVTELAPLGCLLTALRNNRQRFMVSTLCDFMIQV 227
Query: 693 ATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTR-GGKIPVR 751
A+GM YL +IHRDLAARNVL+ S KI DFGL R + S D YT GK+P
Sbjct: 228 ASGMAYLESKRFIHRDLAARNVLLESNEKVKIGDFGLMRAL-SVEDDYYTMNPKGKVPFA 286
Query: 752 WTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGY--RLPAPM 809
W PEA+ +RKF+ ASDVWS GI E+ S+GE P+ + ++ ++ R P
Sbjct: 287 WCPPEALKYRKFSHASDVWSFGICVIELFSYGEEPWPGLNGAQILAKVDMPLCERPLKPS 346
Query: 810 DCPEAVYQLMLD-CWQKERTHRPTFSSIVKTLDKLIRCPDTLRKIAQNRSADPL-----A 863
CP +Y L++ CW + ++R FS + K+L++ +R P +R + S P
Sbjct: 347 HCPSLIYSLLVSLCWAHDPSNRAGFSELKKSLEQ-VR-PHDVRAVHGYDSKSPQNLCFEE 404
Query: 864 GDTPDLIQFTSVEEW 878
GD LI+ ++ W
Sbjct: 405 GDKITLIEASADTSW 419
>UniRef50_A0JMM7 Cluster: Zgc:154019; n=2; Danio rerio|Rep:
Zgc:154019 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 732
Score = 182 bits (442), Expect = 5e-44
Identities = 97/251 (38%), Positives = 141/251 (56%), Gaps = 6/251 (2%)
Query: 587 IGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEASIMGQFEHPNVIF 646
+G G FG V + + P G + VA+KTL+ G + DFL E + M +HPN+I
Sbjct: 117 LGSGSFGVVRKAEWHTPT--GRVLPVAVKTLRSGQVDLVS-DFLQEVTSMQSLDHPNIIH 173
Query: 647 LQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFRVLQLVGMLRGIATGMQYLSEMNYIH 706
L GVV +P+ ++TE GSL LR G++ + +L IA GM+YL +IH
Sbjct: 174 LYGVVLT-HPLKMVTELAPLGSLYDTLRLRHGEYPLSRLWLFSTQIAAGMEYLESRRFIH 232
Query: 707 RDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGGKIPVRWTAPEAIAFRKFTSA 766
RDLAARNVL+ ++ KI DFGL R ++ D T +IP W APE++ F+ A
Sbjct: 233 RDLAARNVLLAAREQVKIGDFGLMRGLDD-RDHYIMTAHRRIPFAWCAPESLRTGSFSHA 291
Query: 767 SDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEK-GYRLPAPMDCPEAVYQLMLDCWQK 825
SDVW G+ WE+ ++ E P+ S + ++ +E+ G RL P DCP+ +Y +M CW
Sbjct: 292 SDVWMFGVTLWEMFTYCEEPWLGLSGRQILYRVEREGERLERPPDCPQELYAVMRKCWAC 351
Query: 826 ERTHRPTFSSI 836
T RPTF+ +
Sbjct: 352 NSTERPTFAQL 362
>UniRef50_A3EXK6 Cluster: Fibroblast growth factor receptor c; n=2;
Nematostella vectensis|Rep: Fibroblast growth factor
receptor c - Nematostella vectensis
Length = 297
Score = 182 bits (442), Expect = 5e-44
Identities = 111/288 (38%), Positives = 156/288 (54%), Gaps = 23/288 (7%)
Query: 576 IDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEASI 635
I S I + +G GEFG V RG++ G +D A+K++K ++E A RD + E +
Sbjct: 11 IPTSNIILHEYLGSGEFGVVTRGEMT--TDDGRTVDCAVKSIKGFASEEALRDLVQELEL 68
Query: 636 MGQF-EHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRANDGKF---RVLQ------- 684
M H N++ L G T +MII EF +G L L G R+ Q
Sbjct: 69 MHSVGHHRNLLNLIGACTDSEKLMIIVEFANDGCLLDLLHQARGDLQSPRIYQNIEPRHS 128
Query: 685 --LVGMLR------GIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIEST 736
++G R +A GM YL+ +HRDLAARNVL+ + V K+ADFGLSR I T
Sbjct: 129 EVVLGQTRRLEIALDVAQGMDYLASKRCVHRDLAARNVLI-ADGVAKVADFGLSRNIYET 187
Query: 737 ADGAYTTRGGKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVI 796
+ TTR GK+P RW + E++ RKFT SDVWS G++ WE+ + G P + +++I
Sbjct: 188 GEYEKTTR-GKLPTRWMSLESLETRKFTLESDVWSYGVLLWEIETRGLTPNAGLNYREMI 246
Query: 797 KSIEKGYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLI 844
KGYRL P DC + +Y++M CW RPTFS IV+ L +L+
Sbjct: 247 ARYRKGYRLERPPDCDQGLYEIMRRCWLAIPKSRPTFSDIVEQLTELL 294
>UniRef50_Q8AXY6 Cluster: Muscle, skeletal receptor tyrosine protein
kinase precursor; n=18; Gnathostomata|Rep: Muscle,
skeletal receptor tyrosine protein kinase precursor -
Gallus gallus (Chicken)
Length = 947
Score = 182 bits (442), Expect = 5e-44
Identities = 100/278 (35%), Positives = 151/278 (54%), Gaps = 22/278 (7%)
Query: 587 IGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEASIMGQFEHPNVIF 646
IG G FG V + + P VA+K LK ++ + DF EA++M +F++PN++
Sbjct: 661 IGEGAFGRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVK 720
Query: 647 LQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFRVLQLVGMLRG--------------- 691
L GV P+ ++ E+M G L+ +LR + + G L
Sbjct: 721 LLGVCAVGKPMCLLFEYMAYGDLNEYLRDRSPRNLCSLVQGGLEARACLLNPLALCCTSQ 780
Query: 692 ------IATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRG 745
+A GM YLSE ++HRDLA RN LV +V KIADFGLSR + S AD
Sbjct: 781 LCIAKQVAAGMAYLSERKFVHRDLATRNCLVGENMVVKIADFGLSRNMYS-ADYYKANEN 839
Query: 746 GKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRL 805
IP+RW PE+I + ++T+ SDVW+ G+V WE+ S+G +PY+ ++++VI + G L
Sbjct: 840 DAIPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSYGMQPYYGMAHEEVIYYVRDGNIL 899
Query: 806 PAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKL 843
P +CP +Y LM CW K RP+F+SI + L+++
Sbjct: 900 SCPDNCPLELYNLMRLCWSKLPADRPSFASIHRILERM 937
>UniRef50_P11362 Cluster: Basic fibroblast growth factor receptor 1
precursor; n=310; Euteleostomi|Rep: Basic fibroblast
growth factor receptor 1 precursor - Homo sapiens
(Human)
Length = 822
Score = 182 bits (442), Expect = 5e-44
Identities = 115/357 (32%), Positives = 178/357 (49%), Gaps = 42/357 (11%)
Query: 535 RPAKTSSNATTPLFAGTGSRTYIDPHTYEDPNQAVREFAREIDASCITIEAIIGGGEFGD 594
RP++ SS+ T P+ AG YE P E R+ ++ G G+
Sbjct: 445 RPSRLSSSGT-PMLAGVSE--------YELPEDPRWELPRD---------RLVLGKPLGE 486
Query: 595 VCRGKLKLPASCGPEID-------VAIKTLKPGSTERARRDFLAEASIMGQF-EHPNVIF 646
C G++ L + G + D VA+K LK +TE+ D ++E +M +H N+I
Sbjct: 487 GCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIIN 546
Query: 647 LQGVVTKCNPIMIITEFMENGSLDTFLRAN---------------DGKFRVLQLVGMLRG 691
L G T+ P+ +I E+ G+L +L+A + + LV
Sbjct: 547 LLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQ 606
Query: 692 IATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGGKIPVR 751
+A GM+YL+ IHRDLAARNVLV V KIADFGL+R+I D T G++PV+
Sbjct: 607 VARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHI-DYYKKTTNGRLPVK 665
Query: 752 WTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDC 811
W APEA+ R +T SDVWS G++ WE+ + G PY +++ K +++G+R+ P +C
Sbjct: 666 WMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNC 725
Query: 812 PEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLIRCPDTLRKIAQNRSADPLAGDTPD 868
+Y +M DCW + RPTF +V+ LD+++ + + D + PD
Sbjct: 726 TNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPD 782
>UniRef50_UPI00015B4221 Cluster: PREDICTED: similar to
tyrosine-protein kinase pr2; n=1; Nasonia
vitripennis|Rep: PREDICTED: similar to tyrosine-protein
kinase pr2 - Nasonia vitripennis
Length = 1345
Score = 181 bits (441), Expect = 7e-44
Identities = 113/301 (37%), Positives = 159/301 (52%), Gaps = 11/301 (3%)
Query: 576 IDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEASI 635
I A I + +G GEFG V +G + + G I VAIK L + +FL EA+I
Sbjct: 169 IPADAIIVNKELGTGEFGVVQQG---VWTNDGERIQVAIKCLSRERMQNNPIEFLKEAAI 225
Query: 636 MGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRAND--GKFRVLQLVGMLRGIA 693
M +H +++ L GVV N +M++TE SL L+ F V L IA
Sbjct: 226 MHSIDHEHIVRLYGVVLDTNSLMLVTELAPLRSLLECLKEPSLRASFPVPSLCDFSVQIA 285
Query: 694 TGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGG--KIPVR 751
GMQYL IHRDLAARN+LV S+ KI+DFGLSR + D T K+P+
Sbjct: 286 DGMQYLEAKRLIHRDLAARNILVFSKNKVKISDFGLSRALGVGKDYYQTNFNVNLKLPIA 345
Query: 752 WTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKG--YRLPAPM 809
W APE I++ KFTSASDVW+ G+ WE+ S+G +P+ + ++++I++ RL P
Sbjct: 346 WCAPECISYLKFTSASDVWAYGVTLWEMFSYGFQPWAALTGHQILEAIDEPNFQRLEQPD 405
Query: 810 DCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLIRCPDTLRKIAQNRSADPLAGDTPDL 869
CP+ + LM CWQ E T RP FS ++ L L P+ ++ + N L D+
Sbjct: 406 CCPKDYFSLMQQCWQHEPTKRPKFSELICLLPDL--KPEQVQAVQDNSEIGQLTYRQGDV 463
Query: 870 I 870
I
Sbjct: 464 I 464
>UniRef50_A7RZ71 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 624
Score = 181 bits (441), Expect = 7e-44
Identities = 108/322 (33%), Positives = 161/322 (50%), Gaps = 18/322 (5%)
Query: 540 SSNATTPLFAGTGSRTYIDPHTYEDPNQAVREFAREIDASCITIEAIIGGGEFGDVCRGK 599
S+N++TPL T ++ D + + EID S ITI+ +G G FG V + +
Sbjct: 293 SANSSTPLIRYRNVTTSSIEESFLDFYELPIDEDWEIDRSQITIKEQLGEGAFGLVMKAE 352
Query: 600 LKLPASCGPEIDVAIKTLKPGSTERARRDFLAEASIMGQF-EHPNVIFLQGVVTKCNPIM 658
VA+K LK +TE D L+E M H N+I L G T+ P+
Sbjct: 353 ALGLTDMPYRHTVAVKMLKADATENELADLLSEMDTMKNIGSHKNIINLIGACTQNGPLY 412
Query: 659 IITEFMENGSLDTFLRA----------------NDGKFRVLQLVGMLRGIATGMQYLSEM 702
++ EF +G+L FLR + V + IA GM+YLS
Sbjct: 413 VVVEFAPHGNLRQFLRERRPSDYHRSRSDSSTHSQPSLIVRDFISFAFQIARGMEYLSFK 472
Query: 703 NYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGGKIPVRWTAPEAIAFRK 762
IHRDLAARN+LV V KIADFGL+R + D G++P++W A EA+ R
Sbjct: 473 KCIHRDLAARNILVGEDYVMKIADFGLARNVRDM-DYYRKATDGRLPIKWLAIEALFDRV 531
Query: 763 FTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEAVYQLMLDC 822
+T+ SDVW+ GI+ WE+ + G PY + + + ++ GYR+ P CP+ +Y +ML C
Sbjct: 532 YTTQSDVWTFGILLWEIFTLGGSPYPGIPVEKLFELLKSGYRMQMPQKCPDKMYDIMLSC 591
Query: 823 WQKERTHRPTFSSIVKTLDKLI 844
W + RP+F+ + DK++
Sbjct: 592 WNENPNARPSFTELRAEFDKML 613
>UniRef50_Q02763 Cluster: Angiopoietin-1 receptor precursor; n=41;
Euteleostomi|Rep: Angiopoietin-1 receptor precursor -
Homo sapiens (Human)
Length = 1124
Score = 181 bits (441), Expect = 7e-44
Identities = 101/286 (35%), Positives = 161/286 (56%), Gaps = 25/286 (8%)
Query: 576 IDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEASI 635
+D + I + +IG G FG V + ++K G +D AIK +K +++ RDF E +
Sbjct: 819 LDWNDIKFQDVIGEGNFGQVLKARIKKD---GLRMDAAIKRMKEYASKDDHRDFAGELEV 875
Query: 636 MGQF-EHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRAN-----DGKFRVL------ 683
+ + HPN+I L G + + E+ +G+L FLR + D F +
Sbjct: 876 LCKLGHHPNIINLLGACEHRGYLYLAIEYAPHGNLLDFLRKSRVLETDPAFAIANSTAST 935
Query: 684 ----QLVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADG 739
QL+ +A GM YLS+ +IHRDLAARN+LV V KIADFGLSR E
Sbjct: 936 LSSQQLLHFAADVARGMDYLSQKQFIHRDLAARNILVGENYVAKIADFGLSRGQE----- 990
Query: 740 AYTTRG-GKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKS 798
Y + G++PVRW A E++ + +T+ SDVWS G++ WE++S G PY + ++ +
Sbjct: 991 VYVKKTMGRLPVRWMAIESLNYSVYTTNSDVWSYGVLLWEIVSLGGTPYCGMTCAELYEK 1050
Query: 799 IEKGYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLI 844
+ +GYRL P++C + VY LM CW+++ RP+F+ I+ +L++++
Sbjct: 1051 LPQGYRLEKPLNCDDEVYDLMRQCWREKPYERPSFAQILVSLNRML 1096
>UniRef50_Q9V6K3 Cluster: Tyrosine-protein kinase transmembrane
receptor Ror2 precursor; n=2; Sophophora|Rep:
Tyrosine-protein kinase transmembrane receptor Ror2
precursor - Drosophila melanogaster (Fruit fly)
Length = 724
Score = 181 bits (441), Expect = 7e-44
Identities = 99/262 (37%), Positives = 146/262 (55%), Gaps = 13/262 (4%)
Query: 587 IGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEASIMGQFEHPNVIF 646
+G G FG V + + ++ VA+K LK ++++ + DF EA ++ +F+HPN++
Sbjct: 447 LGQGAFGRVFQARAPGLVPDQEDLLVAVKMLKDDASDQMQMDFEREACLLAEFDHPNIVR 506
Query: 647 LQGVVTKCNPIMIITEFMENGSLDTFLRANDG------------KFRVLQLVGMLRGIAT 694
L GV P+ ++ E+M G L FLRA + L L+ M IA
Sbjct: 507 LLGVCALGRPMCLLFEYMAPGDLSEFLRACSPYATHQAPTQDRLQLNELHLLQMAANIAA 566
Query: 695 GMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGGKIPVRWTA 754
GM YLSE ++HRDLA RN L+N + KIADFGLS +I D IP+RW
Sbjct: 567 GMLYLSERKFVHRDLATRNCLINEHMAVKIADFGLSHKIY-LQDYYKGDENDFIPIRWMP 625
Query: 755 PEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEA 814
E+I + KF+ SDVW+ GI WEV SF +PY+ ++++VIK I++G L P + P +
Sbjct: 626 LESILYNKFSLESDVWAYGICLWEVFSFALQPYFGLTHEEVIKYIKEGNVLGCPDNTPLS 685
Query: 815 VYQLMLDCWQKERTHRPTFSSI 836
VY LM CW ++ + RP F+ I
Sbjct: 686 VYALMRRCWNRKPSERPGFAEI 707
>UniRef50_UPI00015B4CAE Cluster: PREDICTED: similar to
ENSANGP00000019144; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to ENSANGP00000019144 - Nasonia
vitripennis
Length = 1220
Score = 181 bits (440), Expect = 9e-44
Identities = 100/297 (33%), Positives = 162/297 (54%), Gaps = 19/297 (6%)
Query: 565 PNQAVREFAREIDASCITIEAIIGGGEFGDVCRGKLK-LPASCGPEIDVAIKTLKPGSTE 623
P + +E E + ++ ++G G FG V + + L G VA+KT+K G+++
Sbjct: 906 PPPSSQESRWEFPRDKLRLQTVLGEGNFGQVWKAEADDLTGHQGTTRLVAVKTVKEGASD 965
Query: 624 RARRDFLAEASIMGQF-EHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRANDGK--- 679
R + D + E IM + HPNV+ L G T+ P +I E++ G L +LR + +
Sbjct: 966 REKEDLVRELEIMQRVGSHPNVVTLLGCCTEQEPHYLILEYVMYGKLLAYLRDHRTRQDF 1025
Query: 680 -----------FRVLQLVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFG 728
R L + G +A GM+YL+ IHRDLAARNVLV+ +CKIADFG
Sbjct: 1026 YNFSEDSAALTSRDLTVFGYC--VARGMEYLASKKIIHRDLAARNVLVDHNKLCKIADFG 1083
Query: 729 LSREIESTADGAYTTRG-GKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPY 787
+SR + T G +P+RW APE++ + FT+ +DVWS GI+ WE+++ G PY
Sbjct: 1084 MSRFANEDGEVIETRHGRNALPIRWMAPESLIYSLFTTKTDVWSFGILMWEIVTLGSTPY 1143
Query: 788 WNWSNQDVIKSIEKGYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLI 844
+ + ++V++S++ GYRL P C +++++ CW + RP F + + L +L+
Sbjct: 1144 PDMTAREVMRSVQSGYRLERPSHCRSELFRVIARCWHADPDRRPEFQLLRRDLAQLL 1200
>UniRef50_UPI0000DB6B52 Cluster: PREDICTED: similar to Ror
CG4926-PA; n=3; Endopterygota|Rep: PREDICTED: similar to
Ror CG4926-PA - Apis mellifera
Length = 529
Score = 181 bits (440), Expect = 9e-44
Identities = 115/302 (38%), Positives = 168/302 (55%), Gaps = 26/302 (8%)
Query: 587 IGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEASIMGQFEHPNVIF 646
IG G FG V +G+L + S EI VAIK LK + A DF+ E IM F H N++
Sbjct: 211 IGEGCFGKVYKGELCIGDS--KEI-VAIKVLKETAPREAEEDFMREVDIMSTFGHRNILS 267
Query: 647 LQGVVTK---CNPIMIITEFMENGSLDTFLRANDGKFR-----VLQ------LVGMLRGI 692
L+G V + +P M+ E+M G L LR+N +F +Q L + I
Sbjct: 268 LKGAVLREGNSSPWMVF-EYMPYGDLAEVLRSNSRQFNRSPKPEMQPLTEESLHWITIQI 326
Query: 693 ATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGGKI-PVR 751
A GM YLS ++HRDLA RN LV + KIADFG+SR++ T D Y +G ++ P+R
Sbjct: 327 AAGMTYLSGQRFVHRDLACRNCLVGYDFIVKIADFGMSRDVY-TCD-YYKIKGSRLLPIR 384
Query: 752 WTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQD---VIKSIEKGYRLPAP 808
W +PE++ + +FT SDVWS G+V WEV SFG++PY+ +N++ V+K I +G L P
Sbjct: 385 WMSPESVMYGRFTLESDVWSFGVVLWEVYSFGKQPYYGHNNEEVSKVVKLIFQGIMLIPP 444
Query: 809 MDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLIRCPDTLRKIAQNRSADPLAGDTPD 868
CP V Q+M +CW+ + R F I++ L+K+ T++ P+ TPD
Sbjct: 445 EGCPPFVCQIMRECWKTDPKDRIKFPEILERLEKV--KVKTIQDTLPRPPQGPVTIRTPD 502
Query: 869 LI 870
++
Sbjct: 503 VL 504
>UniRef50_P79950 Cluster: Tyrosine kinase receptor; n=3; Xenopus|Rep:
Tyrosine kinase receptor - Xenopus laevis (African clawed
frog)
Length = 1369
Score = 181 bits (440), Expect = 9e-44
Identities = 93/270 (34%), Positives = 149/270 (55%), Gaps = 6/270 (2%)
Query: 576 IDASCITI--EAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEA 633
I C+T + IIG G FG V G E+ A+K+L + +FL E
Sbjct: 1050 IPERCLTTHRDRIIGKGHFGSVYHGTYVDEDQ--QEVHCAVKSLNRITDLEEVEEFLREG 1107
Query: 634 SIMGQFEHPNVIFLQGVVTKCNPI-MIITEFMENGSLDTFLRANDGKFRVLQLVGMLRGI 692
+M F HPNV+ L G+ + +++ FM++G L F+R+ + V LVG +
Sbjct: 1108 ILMKSFHHPNVLSLIGICLPQEGLPLVVLPFMKHGDLRHFIRSEERNPTVKDLVGFGLQV 1167
Query: 693 ATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREI-ESTADGAYTTRGGKIPVR 751
+ GM+YL+ ++HRDLAARN +++ K+ADFGL+R++ + + ++PV+
Sbjct: 1168 SRGMEYLANRKFVHRDLAARNCMLDESFHVKVADFGLARDVFDKEYYSVRRHKNARLPVK 1227
Query: 752 WTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDC 811
W A E++ +KFT+ SDVWS G++ WE+M+ G PY + D+ + + +G RL P C
Sbjct: 1228 WMAMESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVDAYDITRYLFRGRRLAQPEYC 1287
Query: 812 PEAVYQLMLDCWQKERTHRPTFSSIVKTLD 841
P +Y LML CW + RPTF+ +V ++
Sbjct: 1288 PNPLYSLMLSCWNPQPVERPTFTQLVSDME 1317
>UniRef50_Q7Q0F6 Cluster: Tyrosine-protein kinase receptor; n=2;
Cellia|Rep: Tyrosine-protein kinase receptor - Anopheles
gambiae str. PEST
Length = 1318
Score = 181 bits (440), Expect = 9e-44
Identities = 101/267 (37%), Positives = 153/267 (57%), Gaps = 17/267 (6%)
Query: 587 IGGGEFGDVCRGKLKLPASCGPEIDV--AIKTLKPGSTERARRDFLAEASIMGQFEHPNV 644
+G G FG V +G + G +++V AIKT+ +TER R FL EA+IM +F +V
Sbjct: 999 LGQGSFGMVYKG---IMTKLGNDVNVPCAIKTVTENATERERDSFLIEATIMKEFHTHHV 1055
Query: 645 IFLQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFR-----------VLQLVGMLRGIA 693
+ L GVV+ P ++I E M NG L ++LR + + + Q+ M IA
Sbjct: 1056 VRLYGVVSVGQPTLVIMELMANGDLKSYLRRHRPDYENGEESSPQPPTLKQIYQMAIEIA 1115
Query: 694 TGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGGKIPVRWT 753
GM YL+ ++HRDLAARN +V L KI DFG++R+I T T+G +PVRW
Sbjct: 1116 DGMAYLAAKKFVHRDLAARNCMVAEDLTVKIGDFGMTRDIYETDYYRKGTKGF-LPVRWM 1174
Query: 754 APEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCPE 813
APE++ F+S+SDV+S G+V WE+ + +PY +N V++ + G + P +CP+
Sbjct: 1175 APESLKDGMFSSSSDVFSYGVVLWEMATLASQPYQGLTNDQVLRYVIDGGVMERPENCPD 1234
Query: 814 AVYQLMLDCWQKERTHRPTFSSIVKTL 840
+Y+LM CWQ + RP+F I++ L
Sbjct: 1235 KLYELMRICWQHRASARPSFIDIIRML 1261
>UniRef50_Q7PWP1 Cluster: ENSANGP00000013218; n=2; Culicidae|Rep:
ENSANGP00000013218 - Anopheles gambiae str. PEST
Length = 861
Score = 181 bits (440), Expect = 9e-44
Identities = 102/304 (33%), Positives = 166/304 (54%), Gaps = 20/304 (6%)
Query: 575 EIDASCITIEAIIGGGEFGDVCRG-KLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEA 633
E + + ++A +G GEFG V +G LP G VA+K LK G+ L+E
Sbjct: 481 EFPRTNLILDATLGEGEFGKVLKGFATDLPEKPGITT-VAVKMLKTGANSVELLALLSEY 539
Query: 634 SIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFRVLQ--------- 684
++ + HPNVI L G TK + ++I E+ + GSL +LR + K VL
Sbjct: 540 QLLQEVNHPNVIRLLGACTKGDSPLLIIEYCQYGSLKNYLRLSR-KLEVLNADYENAVEP 598
Query: 685 -----LVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADG 739
++ I+ GM YL+++ +HRDLAARNVL+ VCKI+DFGL+R++ D
Sbjct: 599 ITVKDILSFAWQISKGMAYLTDIKLVHRDLAARNVLLAEGKVCKISDFGLTRDVYE--DD 656
Query: 740 AYTTRG-GKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKS 798
AY + ++PV+W APE++A +T+ SDVW+ G++CWE+++ G PY Q++
Sbjct: 657 AYLKKSKDRVPVKWMAPESLADHIYTTKSDVWAFGVLCWELITLGASPYPGIPPQNLYNL 716
Query: 799 IEKGYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLIRCPDTLRKIAQNRS 858
+++GYR+ P +C E +Y ++ CW + RP+F + + L+ + QN
Sbjct: 717 LKQGYRMECPKNCSEEIYGIVRLCWADDPKQRPSFKHLAGQFELLLGRSAKYLDMEQNSI 776
Query: 859 ADPL 862
++P+
Sbjct: 777 SNPV 780
>UniRef50_P35590 Cluster: Tyrosine-protein kinase receptor Tie-1
precursor; n=37; Deuterostomia|Rep: Tyrosine-protein
kinase receptor Tie-1 precursor - Homo sapiens (Human)
Length = 1138
Score = 181 bits (440), Expect = 9e-44
Identities = 107/281 (38%), Positives = 151/281 (53%), Gaps = 25/281 (8%)
Query: 581 ITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEASIMGQF- 639
IT E +IG G FG V R +K G +++ AIK LK ++E RDF E ++ +
Sbjct: 839 ITFEDLIGEGNFGQVIRAMIKKD---GLKMNAAIKMLKEYASENDHRDFAGELEVLCKLG 895
Query: 640 EHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRAN------------DGKFRVL---Q 684
HPN+I L G + I E+ G+L FLR + G L Q
Sbjct: 896 HHPNIINLLGACKNRGYLYIAIEYAPYGNLLDFLRKSRVLETDPAFAREHGTASTLSSRQ 955
Query: 685 LVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTR 744
L+ A GMQYLSE +IHRDLAARNVLV L KIADFGLSR E Y +
Sbjct: 956 LLRFASDAANGMQYLSEKQFIHRDLAARNVLVGENLASKIADFGLSRGEE-----VYVKK 1010
Query: 745 G-GKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGY 803
G++PVRW A E++ + +T+ SDVWS G++ WE++S G PY + ++ + + +GY
Sbjct: 1011 TMGRLPVRWMAIESLNYSVYTTKSDVWSFGVLLWEIVSLGGTPYCGMTCAELYEKLPQGY 1070
Query: 804 RLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLI 844
R+ P +C + VY+LM CW+ RP F+ I L +++
Sbjct: 1071 RMEQPRNCDDEVYELMRQCWRDRPYERPPFAQIALQLGRML 1111
>UniRef50_P13368 Cluster: Protein sevenless; n=20; Eumetazoa|Rep:
Protein sevenless - Drosophila melanogaster (Fruit fly)
Length = 2554
Score = 181 bits (440), Expect = 9e-44
Identities = 111/322 (34%), Positives = 173/322 (53%), Gaps = 33/322 (10%)
Query: 575 EIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEAS 634
+I+ S + + +G G FG+V G+LK S P+ VAIK+L+ G++E A + L EA
Sbjct: 2203 QINWSQLKLLRFLGSGAFGEVYEGQLKTEDSEEPQ-RVAIKSLRKGASEFA--ELLQEAQ 2259
Query: 635 IMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRANDGK----------FRVLQ 684
+M F+H N++ L G+ I +I E ME G L ++LRA + +
Sbjct: 2260 LMSNFKHENIVCLVGICFDTESISLIMEHMEAGDLLSYLRAARATSTQEPQPTAGLSLSE 2319
Query: 685 LVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQL-------VCKIADFGLSREIESTA 737
L+ M +A G YL +M+++HRDLA RN LV KI DFGL+R+I +
Sbjct: 2320 LLAMCIDVANGCSYLEDMHFVHRDLACRNCLVTESTGSTDRRRTVKIGDFGLARDIYKS- 2378
Query: 738 DGAYTTRG-GKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVI 796
Y G G +PVRW +PE++ FT+ SDVW+ G++CWE+++ G++PY +N +V+
Sbjct: 2379 -DYYRKEGEGLLPVRWMSPESLVDGLFTTQSDVWAFGVLCWEILTLGQQPYAARNNFEVL 2437
Query: 797 KSIEKGYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLIRCPDTLRKIAQN 856
+++G RL P C E +Y L+L CW+ + RP+F RC +TL I+ +
Sbjct: 2438 AHVKEGGRLQQPPMCTEKLYSLLLLCWRTDPWERPSFR----------RCYNTLHAISTD 2487
Query: 857 RSADPLAGDTPDLIQFTSVEEW 878
+A T D + S E+
Sbjct: 2488 LRRTQMASATADTVVSCSRPEF 2509
>UniRef50_Q9VZI2 Cluster: CG14992-PA; n=3; Sophophora|Rep:
CG14992-PA - Drosophila melanogaster (Fruit fly)
Length = 1073
Score = 180 bits (439), Expect = 1e-43
Identities = 108/306 (35%), Positives = 154/306 (50%), Gaps = 7/306 (2%)
Query: 581 ITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERAR--RDFLAEASIMGQ 638
IT+ +G G FG V RG+ + G I VA+K LK + + DF E M
Sbjct: 123 ITMGLKLGDGSFGVVRRGEWSA-SPAGKVIPVAVKVLKSDNLTQPGIIDDFFREVQAMHA 181
Query: 639 FEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRANDGKFRVLQLVGMLRGIATGMQY 698
+H N++ L GVV P+M+ITE E GSL LR + + I TGM Y
Sbjct: 182 LDHANLVRLYGVVLS-QPMMMITELAERGSLLDTLRKQCRHTSLTIIWNWSVQIVTGMAY 240
Query: 699 LSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGGKIPVRWTAPEAI 758
L + ++HRDLA RNVL+ + KI DFGL R + D + K+P W APE++
Sbjct: 241 LEQKRFLHRDLACRNVLLAAGNKIKIGDFGLMRALPQEDDCYVMSEHKKVPFPWCAPESL 300
Query: 759 AFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEK-GYRLPAPMDCPEAVYQ 817
FR+F+ ASD W G+ WE+ SFGE P+ + +++ I++ G RL P CP VY
Sbjct: 301 RFRQFSHASDTWMFGVTLWEMFSFGEDPWVGLNGSQILRKIDREGERLHQPDACPPDVYA 360
Query: 818 LMLDCWQKERTHRPTFSSIVKTLDKLIRCPDTLRKIAQNRSADPLAGDTPDLIQFTSVEE 877
+ML CW K RPTF+++ + L + P +R + + L + D I
Sbjct: 361 MMLQCWDKTPAERPTFAALKEYLASM--SPPVMRASRSHHESKGLQIEPGDTIAIIDGRH 418
Query: 878 WLECIK 883
L+ IK
Sbjct: 419 ELKLIK 424
>UniRef50_Q4H3N3 Cluster: Epidermal growth factor receptor; n=1; Ciona
intestinalis|Rep: Epidermal growth factor receptor -
Ciona intestinalis (Transparent sea squirt)
Length = 1462
Score = 180 bits (439), Expect = 1e-43
Identities = 107/306 (34%), Positives = 164/306 (53%), Gaps = 13/306 (4%)
Query: 552 GSRTYIDPHTYE-DPNQAVREFA--REIDASCITIEAIIGGGEFGDVCRGKLKLPASCGP 608
G R ++P P+ A A R + S + ++G G FG V + + P +
Sbjct: 803 GERIPLEPEAVPLTPSGAAPNVAQLRIVKESELEFRKMLGSGAFGTVQKA-IWTPLNIQG 861
Query: 609 E---IDVAIKTLKPGST--ERARRDFLAEASIMGQFEHPNVIFLQGVVTKCNPIMIITEF 663
E I VA+KTLK + A + + EA +M E P ++ L G+ + + +IT+
Sbjct: 862 EKVKIAVAVKTLKTSEDLLQSANNEIMDEAYMMASVECPYLVRLLGI-SMTEQVALITQL 920
Query: 664 MENGSLDTFLR--ANDGKFRVLQLVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLV 721
M GSL ++R R Q++ IA GM+YL E + +HRDLAARNVLV +
Sbjct: 921 MPLGSLLEYVRNPTTRDSIRSRQILSWCVQIAKGMKYLEEKHLVHRDLAARNVLVKTPNH 980
Query: 722 CKIADFGLSREIESTADGAYTTRGGKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMS 781
KI DFGL++ ++ T + Y GGK+P++W A E I R+F+ SDVW+ G+ CWE+++
Sbjct: 981 VKITDFGLAKMLD-TKEEIYHAEGGKLPIKWLAIECITEREFSHLSDVWAFGVTCWELLT 1039
Query: 782 FGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLD 841
FG RPY DV+ +E+G RLP P +Y +++ CW +R RP+FS++V
Sbjct: 1040 FGARPYEGVRAVDVLSLLERGDRLPQPATSTIDIYMVLVKCWMVDRLCRPSFSNLVDEFS 1099
Query: 842 KLIRCP 847
K+ P
Sbjct: 1100 KMAADP 1105
>UniRef50_P30530 Cluster: Tyrosine-protein kinase receptor UFO
precursor; n=37; Euteleostomi|Rep: Tyrosine-protein
kinase receptor UFO precursor - Homo sapiens (Human)
Length = 887
Score = 180 bits (439), Expect = 1e-43
Identities = 106/285 (37%), Positives = 163/285 (57%), Gaps = 22/285 (7%)
Query: 576 IDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERAR-RDFLAEAS 634
+D + + +G GEFG V G+L S + VA+KT+K R+ DFL+EA
Sbjct: 524 VDRHKVALGKTLGEGEFGAVMEGQLNQDDSI---LKVAVKTMKIAICTRSELEDFLSEAV 580
Query: 635 IMGQFEHPNVIFLQGVVTKCN-------PIMIITEFMENGSLDTFL---RANDGKFRV-- 682
M +F+HPNV+ L GV + + P++I+ FM++G L +FL R D +
Sbjct: 581 CMKEFDHPNVMRLIGVCFQGSERESFPAPVVILP-FMKHGDLHSFLLYSRLGDQPVYLPT 639
Query: 683 LQLVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYT 742
LV + IA+GM+YLS +IHRDLAARN ++N + +ADFGLS++I + G Y
Sbjct: 640 QMLVKFMADIASGMEYLSTKRFIHRDLAARNCMLNENMSVCVADFGLSKKIYN---GDYY 696
Query: 743 TRG--GKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIE 800
+G K+PV+W A E++A R +TS SDVWS G+ WE+ + G+ PY N ++ +
Sbjct: 697 RQGRIAKMPVKWIAIESLADRVYTSKSDVWSFGVTMWEIATRGQTPYPGVENSEIYDYLR 756
Query: 801 KGYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLIR 845
+G RL P DC + +Y LM CW+ RP+F+ + + L+ ++
Sbjct: 757 QGNRLKQPADCLDGLYALMSRCWELNPQDRPSFTELREDLENTLK 801
>UniRef50_UPI0000E47617 Cluster: PREDICTED: similar to muscle
specific tyrosine kinase receptor; n=1;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
muscle specific tyrosine kinase receptor -
Strongylocentrotus purpuratus
Length = 827
Score = 180 bits (437), Expect = 2e-43
Identities = 99/279 (35%), Positives = 152/279 (54%), Gaps = 14/279 (5%)
Query: 575 EIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEAS 634
E + + + E IG G FG V + E VA+K LK + + F EA
Sbjct: 533 EYNRNNVIYEKDIGEGAFGRVFMASAPKLVAGEAETSVAVKMLKATADKVVTEYFNREAQ 592
Query: 635 IMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFL------RAND-------GKFR 681
++ +F H N++ L GV P+ ++ E+M G L+ +L R+N +
Sbjct: 593 MIARFSHQNIVKLLGVCFVGRPLCLLLEYMSEGDLEDYLHSRSPHRSNSRTSNSPGSGLK 652
Query: 682 VLQLVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAY 741
+ + M + IA GM YL+EM ++HRD+A RN L+NS+ KI+DFGL+R + +
Sbjct: 653 TYEKLNMAKQIACGMAYLNEMMFVHRDIATRNCLINSRTDVKISDFGLARYV-GHKECFV 711
Query: 742 TTRGGKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEK 801
+ IP+RWTAPEA+ +FT ASDVWS G++ WE+ S+ E+PY N S++DV +
Sbjct: 712 GHKEEHIPIRWTAPEALWDYQFTYASDVWSFGVLLWELFSYAEQPYLNLSHEDVFLHTRQ 771
Query: 802 GYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTL 840
GYRL + + P+ V+Q+M +CWQ RP F + +L
Sbjct: 772 GYRLSSLENTPQKVHQIMGECWQANPADRPFFKQLQDSL 810
>UniRef50_UPI0000D55449 Cluster: PREDICTED: similar to CG7223-PA,
isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG7223-PA, isoform A - Tribolium castaneum
Length = 861
Score = 180 bits (437), Expect = 2e-43
Identities = 104/288 (36%), Positives = 156/288 (54%), Gaps = 19/288 (6%)
Query: 575 EIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEAS 634
EI S + + +G G FG V + + G VA+K LK G T+ D ++E
Sbjct: 527 EIPRSMLCLGKSLGEGAFGKVVKAEAVGLLKPGASSIVAVKMLKEGHTDNEMMDLVSEME 586
Query: 635 IMGQF-EHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRAN-------------DGKF 680
+M +H N+I L G T+ P+ ++ E+ G+L FLR + + +
Sbjct: 587 MMKMIGKHNNIINLLGCCTQGGPLYVVVEYAPYGNLRDFLRQHRPSSGYEPAIGLEEKEK 646
Query: 681 RVL---QLVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTA 737
+ L LV +A GM+YL+ IHRDLAARNVLV+ KIADFGL+R+I
Sbjct: 647 KTLTQKDLVSFAYQVARGMEYLASRRCIHRDLAARNVLVSDDYFLKIADFGLARDIHCN- 705
Query: 738 DGAYTTRGGKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNW-SNQDVI 796
D T G++PV+W APEA+ R +T+ SDVWS GI+ WE+M+ G PY + S + +
Sbjct: 706 DYYRKTTDGRLPVKWMAPEALFHRVYTTQSDVWSYGILLWEIMTLGGTPYPSVPSVEKLF 765
Query: 797 KSIEKGYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLI 844
+ + G+R+ P C +Y LM +CW + RPTFS +V+ LD+++
Sbjct: 766 QLLRNGHRMEKPPCCSLEIYMLMRECWSYKPNERPTFSQLVEDLDRIL 813
>UniRef50_Q17JW1 Cluster: Tyrosine protein kinase; n=2;
Culicidae|Rep: Tyrosine protein kinase - Aedes aegypti
(Yellowfever mosquito)
Length = 722
Score = 180 bits (437), Expect = 2e-43
Identities = 103/274 (37%), Positives = 147/274 (53%), Gaps = 17/274 (6%)
Query: 575 EIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPE--IDVAIKTLKPGSTERARRDFLAE 632
E+ + I +G G FG V G+ A G E VA+KTLK GST + DFL+E
Sbjct: 287 EVPKDRVVINRRLGEGAFGTVYGGE----AQIGDEGWTAVAVKTLKIGSTTEDKVDFLSE 342
Query: 633 ASIMGQFEHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRAN----------DGKFRV 682
A M +F+H N++ L GV + P+ I EFM G L T+L A D
Sbjct: 343 AEAMKRFDHNNIVKLLGVCLQTEPVYTIMEFMLYGDLKTYLLARRHLVNSKQSEDSDISP 402
Query: 683 LQLVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYT 742
+L M ++ + YL+E Y+HRDLA RN +VN+Q V K+ DFG++R D
Sbjct: 403 KRLTMMALDVSRALSYLAEQKYVHRDLACRNCMVNAQRVVKLGDFGMARPTFEN-DYYRF 461
Query: 743 TRGGKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKG 802
R G +PVRW APE++A FT ASDVWS G++ +E++SFG PY +N V++ +++G
Sbjct: 462 NRKGMLPVRWMAPESLALGIFTPASDVWSYGVLLYEIISFGSFPYQGMTNNQVLEHVKEG 521
Query: 803 YRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSI 836
L P + LM CW ++ RP+ S +
Sbjct: 522 NCLTIPTGVKPQLEGLMKACWNQDYKKRPSASEV 555
>UniRef50_Q59F30 Cluster: Fibroblast growth factor receptor 4
variant; n=28; Eumetazoa|Rep: Fibroblast growth factor
receptor 4 variant - Homo sapiens (Human)
Length = 1034
Score = 180 bits (437), Expect = 2e-43
Identities = 104/276 (37%), Positives = 146/276 (52%), Gaps = 19/276 (6%)
Query: 587 IGGGEFGDVCRGKL--KLPASCGPEIDVAIKTLKPGSTERARRDFLAEASIMGQF-EHPN 643
+G G FG V R + PA VA+K LK ++++ D ++E +M H N
Sbjct: 705 LGEGCFGQVVRAEAFGMDPARPDQASTVAVKMLKDNASDKDLADLVSEMEVMKLIGRHKN 764
Query: 644 VIFLQGVVTKCNPIMIITEFMENGSLDTFLRA---------------NDGKFRVLQLVGM 688
+I L GV T+ P+ +I E G+L FLRA ++G LV
Sbjct: 765 IINLLGVCTQEGPLYVIVECAAKGNLREFLRARRPPGPDLSPDGPRSSEGPLSFPVLVSC 824
Query: 689 LRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGGKI 748
+A GMQYL IHRDLAARNVLV V KIADFGL+R + D T G++
Sbjct: 825 AYQVARGMQYLESRKCIHRDLAARNVLVTEDNVMKIADFGLARGVHHI-DYYKKTSNGRL 883
Query: 749 PVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAP 808
PV+W APEA+ R +T SDVWS GI+ WE+ + G PY +++ + +G+R+ P
Sbjct: 884 PVKWMAPEALFDRVYTHQSDVWSFGILLWEIFTLGGSPYPGIPVEELFSLLREGHRMDRP 943
Query: 809 MDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLI 844
CP +Y LM +CW + RPTF +V+ LDK++
Sbjct: 944 PHCPPELYGLMRECWHAAPSQRPTFKQLVEALDKVL 979
>UniRef50_Q3TJ05 Cluster: 14 days pregnant adult female placenta
cDNA, RIKEN full-length enriched library,
clone:I530025O09 product:fibroblast growth factor
receptor 1, full insert sequence; n=18; Eumetazoa|Rep:
14 days pregnant adult female placenta cDNA, RIKEN
full-length enriched library, clone:I530025O09
product:fibroblast growth factor receptor 1, full insert
sequence - Mus musculus (Mouse)
Length = 386
Score = 179 bits (436), Expect = 3e-43
Identities = 114/357 (31%), Positives = 177/357 (49%), Gaps = 42/357 (11%)
Query: 535 RPAKTSSNATTPLFAGTGSRTYIDPHTYEDPNQAVREFAREIDASCITIEAIIGGGEFGD 594
RP++ SS+ T P+ AG YE P E R+ ++ G G+
Sbjct: 9 RPSRLSSSGT-PMLAGVSE--------YELPEDPRWELPRD---------RLVLGKPLGE 50
Query: 595 VCRGKLKLPASCGPEID-------VAIKTLKPGSTERARRDFLAEASIMGQF-EHPNVIF 646
C G++ L + G + D VA+K LK +TE+ D ++E +M +H N+I
Sbjct: 51 GCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIIN 110
Query: 647 LQGVVTKCNPIMIITEFMENGSLDTFLRAN---------------DGKFRVLQLVGMLRG 691
L G T+ P+ +I E+ G+L +L+A + + LV
Sbjct: 111 LLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQ 170
Query: 692 IATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGGKIPVR 751
+A GM+YL+ IHRDLAARN LV V KIADFGL+R+I D T G++PV+
Sbjct: 171 VARGMEYLASKKCIHRDLAARNALVTEDNVMKIADFGLARDIHHI-DYYKKTTNGRLPVK 229
Query: 752 WTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDC 811
W APEA+ R +T SDVWS G++ WE+ + G PY +++ K +++G+R+ P +C
Sbjct: 230 WMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNC 289
Query: 812 PEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLIRCPDTLRKIAQNRSADPLAGDTPD 868
+Y +M DCW + RPTF +V+ LD+++ + + D + PD
Sbjct: 290 TNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSIPLDQYSPSFPD 346
>UniRef50_Q5RIU8 Cluster: Novel protein similar to vertebrate
discoidin domain receptor family, member 2; n=4; Danio
rerio|Rep: Novel protein similar to vertebrate discoidin
domain receptor family, member 2 - Danio rerio
(Zebrafish) (Brachydanio rerio)
Length = 804
Score = 179 bits (435), Expect = 4e-43
Identities = 111/321 (34%), Positives = 172/321 (53%), Gaps = 33/321 (10%)
Query: 551 TGSRTYIDPHTYEDPNQAVREFAREIDASCITIEAIIGGGEFGDV--CRGK--------- 599
TGS Y P D E + +G G+FG+V C +
Sbjct: 479 TGSNMYSVPALTVDSLTRKDISVAEFPRQRLLFREKLGEGQFGEVHLCEAEGLAEFLGEG 538
Query: 600 LKLPASCGPEIDVAIKTLKPGSTERARRDFLAEASIMGQFEHPNVIFLQGVVTKCNPIMI 659
LP G + VA+K L+ +T AR DFL E IM + +PN+I L V +P+ +
Sbjct: 539 APLPEQDGRPVLVAVKQLRADATSNARNDFLKEIKIMSRLNNPNIIQLLCVCVSSDPLCM 598
Query: 660 ITEFMENGSLDTFL----------RAND-GKFRVLQLVGMLRGIATGMQYLSEMNYIHRD 708
+TE+MENG L+ FL AN+ + L+ M I++GM+YL+ +N++HRD
Sbjct: 599 VTEYMENGDLNMFLSQREIESTLTHANNIPSVSIADLLHMSVQISSGMKYLASLNFVHRD 658
Query: 709 LAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRG-GKIPVRWTAPEAIAFRKFTSAS 767
LA RN L++ L KI+DFG+SR + S+ Y +G +P+RW A E+I KFT+AS
Sbjct: 659 LATRNCLLDRHLTIKISDFGMSRNLYSS--DYYRIQGRAVLPIRWMAWESILLGKFTTAS 716
Query: 768 DVWSMGIVCWEVMSF-GERPYWNWSNQDVIKSIEKGYR-------LPAPMDCPEAVYQLM 819
DVW+ G+ WE+ + E+PY S++ VI++ + +R L AP CP ++++LM
Sbjct: 717 DVWAFGVTLWEIFTLCKEQPYSLLSDEQVIENTGEFFRNQGRQIFLSAPPLCPSSLFKLM 776
Query: 820 LDCWQKERTHRPTFSSIVKTL 840
+ CW ++ T RP+F+ + + L
Sbjct: 777 MRCWSRDITDRPSFNKLHQAL 797
>UniRef50_Q17J18 Cluster: Tyrosine-protein kinase; n=4;
Endopterygota|Rep: Tyrosine-protein kinase - Aedes
aegypti (Yellowfever mosquito)
Length = 959
Score = 178 bits (434), Expect = 5e-43
Identities = 111/303 (36%), Positives = 162/303 (53%), Gaps = 27/303 (8%)
Query: 562 YEDPNQAVREFAREIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGS 621
YE P EF R S + + +G G FG V + VA+K LK G
Sbjct: 611 YEFPIDLNWEFPR----SKLVLGKSLGEGAFGKVVMAEANGLVKGQASTVVAVKMLKEGH 666
Query: 622 TERARRDFLAEASIMGQF-EHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLRAN---- 676
T+ +D + E +M +H N+I L G K P+ +I E+ +G+L FLR++
Sbjct: 667 TDADVKDLVCEMEVMKMIGKHVNIINLLGCCCKDGPLYVIVEYAPHGNLKDFLRSHRFGT 726
Query: 677 ---------DGKFRVL---QLVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKI 724
+ + ++L +L+ IA GM++L+ IHRDLAARNVLV+ V KI
Sbjct: 727 ANYEDMISGEKEKKILTQKELISFAYQIARGMEHLASRRCIHRDLAARNVLVSDGYVMKI 786
Query: 725 ADFGLSREIESTADGAYTTRGGKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGE 784
ADFGL+R+I S TT GK+P+RW APE++ + + S SDVWS G++ WE+M+ G
Sbjct: 787 ADFGLARDIHSQEYYRKTTT-GKLPIRWMAPESLEEKFYDSQSDVWSFGVLLWEIMTLGG 845
Query: 785 RPYWN---WSNQDVIKSIEKGYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLD 841
PY + W N +++ ++KG RL P C +Y M +CW RPTFS IV+ LD
Sbjct: 846 NPYSSIPTWDN--LLEHLKKGKRLEQPPLCSIDIYLFMRECWHYRPEERPTFSEIVQHLD 903
Query: 842 KLI 844
+L+
Sbjct: 904 RLV 906
>UniRef50_Q06418 Cluster: Tyrosine-protein kinase receptor TYRO3
precursor; n=30; Tetrapoda|Rep: Tyrosine-protein kinase
receptor TYRO3 precursor - Homo sapiens (Human)
Length = 890
Score = 178 bits (434), Expect = 5e-43
Identities = 107/277 (38%), Positives = 156/277 (56%), Gaps = 19/277 (6%)
Query: 582 TIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERAR-RDFLAEASIMGQFE 640
T+ ++G GEFG V +LK G + VA+K LK + +FL EA+ M +F+
Sbjct: 519 TLGRMLGKGEFGSVREAQLK--QEDGSFVKVAVKMLKADIIASSDIEEFLREAACMKEFD 576
Query: 641 HPNVIFLQGVVTKCN-----PI-MIITEFMENGSLDTFL---RANDGKFRV-LQ-LVGML 689
HP+V L GV + PI M+I FM++G L FL R + F + LQ L+ +
Sbjct: 577 HPHVAKLVGVSLRSRAKGRLPIPMVILPFMKHGDLHAFLLASRIGENPFNLPLQTLIRFM 636
Query: 690 RGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRG--GK 747
IA GM+YLS N+IHRDLAARN ++ + +ADFGLSR+I S G Y +G K
Sbjct: 637 VDIACGMEYLSSRNFIHRDLAARNCMLAEDMTVCVADFGLSRKIYS---GDYYRQGCASK 693
Query: 748 IPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPA 807
+PV+W A E++A +T SDVW+ G+ WE+M+ G+ PY N ++ + G RL
Sbjct: 694 LPVKWLALESLADNLYTVQSDVWAFGVTMWEIMTRGQTPYAGIENAEIYNYLIGGNRLKQ 753
Query: 808 PMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLI 844
P +C E VY LM CW + RP+F+ + L+ ++
Sbjct: 754 PPECMEDVYDLMYQCWSADPKQRPSFTCLRMELENIL 790
>UniRef50_Q64GK4 Cluster: C-Met receptor tyrosine kinase; n=9;
Clupeocephala|Rep: C-Met receptor tyrosine kinase - Danio
rerio (Zebrafish) (Brachydanio rerio)
Length = 1382
Score = 178 bits (433), Expect = 7e-43
Identities = 93/264 (35%), Positives = 150/264 (56%), Gaps = 6/264 (2%)
Query: 583 IEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEASIMGQFEHP 642
+ IIG G FG V G L P G + AIK+L + FL E I+ F HP
Sbjct: 1081 VNEIIGRGHFGCVFHGTLLEPD--GQKQHCAIKSLNRITDIEEVSQFLKEGIIVKDFSHP 1138
Query: 643 NVIFLQGVV--TKCNPIMIITEFMENGSLDTFLRANDGKFRVLQLVGMLRGIATGMQYLS 700
NV+ L G+ ++ +P++++ +M++G L F+R V L+G +A GM+YL+
Sbjct: 1139 NVLSLLGICLPSEGSPLVVLP-YMKHGDLRNFIRDESHNPTVKDLMGFGLQVAKGMEYLA 1197
Query: 701 EMNYIHRDLAARNVLVNSQLVCKIADFGLSREI-ESTADGAYTTRGGKIPVRWTAPEAIA 759
++HRDLAARN +++ K+AD GL+R++ + + G K+PV+W A E++
Sbjct: 1198 SKKFVHRDLAARNCMLDESYTVKVADVGLARDVYDKEYYSVHNKHGVKLPVKWMALESLQ 1257
Query: 760 FRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEAVYQLM 819
KFT+ SDVWS G++ WE+M+ G PY + ++ D+ + +G RL P CP+A+Y +M
Sbjct: 1258 THKFTTKSDVWSFGVLLWELMTRGAPPYSDVNSFDITVFLLQGRRLLQPEFCPDALYNVM 1317
Query: 820 LDCWQKERTHRPTFSSIVKTLDKL 843
++CW + RPTF +V + +
Sbjct: 1318 IECWHPKPERRPTFLELVSRISAI 1341
>UniRef50_Q1JUB8 Cluster: Fibroblast growth factor receptor; n=2;
Obtectomera|Rep: Fibroblast growth factor receptor -
Bombyx mori (Silk moth)
Length = 856
Score = 178 bits (433), Expect = 7e-43
Identities = 101/286 (35%), Positives = 156/286 (54%), Gaps = 17/286 (5%)
Query: 575 EIDASCITIEAIIGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEAS 634
E+ +++ ++G GEFG V + + G + VA+K LK G T+ ++E
Sbjct: 534 EVPRESLSLGKVLGEGEFGKVVKAECIGILKPGLQSVVAVKMLKEGHTDAEMMALVSEME 593
Query: 635 IMGQF-EHPNVIFLQGVVTKCNPIMIITEFMENGSLDTFLR----------ANDG---KF 680
+M +H N+I L G T+ P+ +I E+ NG+L FLR N+ K
Sbjct: 594 MMKMIGKHVNIINLLGCCTQDGPLYVIVEYAPNGNLREFLRNHRPGNRYESPNEDLKEKK 653
Query: 681 RVLQ--LVGMLRGIATGMQYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTAD 738
+ Q LV +A GM+YL+ IHRD AARNVLV+ V KIADFGL++++ S D
Sbjct: 654 TLTQKDLVSFSYQVARGMEYLASRRCIHRDSAARNVLVSDDCVLKIADFGLAKDVHSN-D 712
Query: 739 GAYTTRGGKIPVRWTAPEAIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKS 798
G++PVRW APE++ + FT+ +DVWS G++ WE+M+ G PY Q + +
Sbjct: 713 YYRKKTEGRLPVRWMAPESLYHKVFTTQTDVWSFGVLLWEIMTLGGTPYPTVPGQYMYQH 772
Query: 799 IEKGYRLPAPMDCPEAVYQLMLDCWQKERTHRPTFSSIVKTLDKLI 844
+ G+R+ P C +Y LM +CW RP+F+ +V+ LDK++
Sbjct: 773 LSAGHRMEKPPCCSLEIYMLMRECWSFSPGDRPSFTELVEDLDKIL 818
>UniRef50_Q93105 Cluster: Insulin-like receptor precursor (EC
2.7.10.1) (MIR) [Contains: Insulin-like receptor alpha
chain; Insulin-like receptor beta chain]; n=2; Aedes
aegypti|Rep: Insulin-like receptor precursor (EC
2.7.10.1) (MIR) [Contains: Insulin-like receptor alpha
chain; Insulin-like receptor beta chain] - Aedes aegypti
(Yellowfever mosquito)
Length = 1390
Score = 178 bits (433), Expect = 7e-43
Identities = 101/264 (38%), Positives = 149/264 (56%), Gaps = 11/264 (4%)
Query: 587 IGGGEFGDVCRGKLKLPASCGPEIDVAIKTLKPGSTERARRDFLAEASIMGQFEHPNVIF 646
+G G FG V +G L AIKT+ +T R + FL EAS+M QF +V+
Sbjct: 1031 LGQGSFGMVYKGILTQLRGEKCNQPCAIKTVNESATAREKDSFLLEASVMKQFNTHHVVR 1090
Query: 647 LQGVVTKCNPIMIITEFMENGSLDTFLRAN--DGKFR--------VLQLVGMLRGIATGM 696
L GVV++ +P ++I E M NG L ++LR + D + R + Q++ M IA G+
Sbjct: 1091 LLGVVSQGDPTLVIMELMANGDLKSYLRRHRPDYEMRRSIRQPPTLRQIIQMAIEIADGI 1150
Query: 697 QYLSEMNYIHRDLAARNVLVNSQLVCKIADFGLSREIESTADGAYTTRGGKIPVRWTAPE 756
LS ++HRDLAARN +V + KI DFG++R+I T T+G +PVRW APE
Sbjct: 1151 GVLSAKKFVHRDLAARNCMVADDMTVKIGDFGMTRDIYETDYYRKGTKGF-LPVRWMAPE 1209
Query: 757 AIAFRKFTSASDVWSMGIVCWEVMSFGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEAVY 816
++ F+S+SDV+S G+V WE+ + +PY +N V++ + G + P +CP+ +Y
Sbjct: 1210 SLKDGIFSSSSDVFSYGVVLWEMATLASQPYQGLTNDQVLRYVIDGGVMERPENCPDNLY 1269
Query: 817 QLMLDCWQKERTHRPTFSSIVKTL 840
LM CWQ T RPTF I+ L
Sbjct: 1270 NLMRRCWQHRPTARPTFMEIISEL 1293
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.413
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 1,083,781,748
Number of Sequences: 1657284
Number of extensions: 46715297
Number of successful extensions: 127479
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 4486
Number of HSP's successfully gapped in prelim test: 5744
Number of HSP's that attempted gapping in prelim test: 105217
Number of HSP's gapped (non-prelim): 15847
length of query: 945
length of database: 575,637,011
effective HSP length: 108
effective length of query: 837
effective length of database: 396,650,339
effective search space: 331996333743
effective search space used: 331996333743
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 77 (35.1 bits)
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