GeneModel BLAST Result against human

BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA002074-TA|BGIBMGA002074-PA|IPR013769|HCO3- transporter,
cytoplasmic, IPR011531|HCO3-transporter, c-terminal, IPR003020|HCO3-
transporter, eukaryote, IPR001717|Anion exchange protein
         (853 letters)

Database: human 
           224,733 sequences; 73,234,838 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

AY142112-1|AAN34939.1| 1259|Homo sapiens anion exchanger SLC4A3 ...   627   e-179
U05596-1|AAA50748.1| 1232|Homo sapiens anion exchanger 3 brain i...   625   e-178
U76669-3|AAF19584.2| 1227|Homo sapiens anion exchanger 2 type b1...   612   e-174
U76669-2|AAF23240.1| 1232|Homo sapiens anion exchanger 2 type b2...   612   e-174
U76669-1|AAF19583.2| 1241|Homo sapiens anion exchanger 2 type a ...   612   e-174
U62531-1|AAC50964.1| 1241|Homo sapiens AE2 anion exchanger protein.   612   e-174
DQ149844-1|AAZ38724.1| 1241|Homo sapiens solute carrier family 4...   612   e-174
BC010069-1|AAH10069.1| 1087|Homo sapiens SLC4A2 protein protein.      612   e-174
BC009434-1|AAH09434.1| 1227|Homo sapiens SLC4A2 protein protein.      612   e-174
BC009386-1|AAH09386.1| 1227|Homo sapiens SLC4A2 protein protein.      612   e-174
BC004893-1|AAH04893.1| 1087|Homo sapiens SLC4A2 protein protein.      612   e-174
AB209158-1|BAD92395.1| 1244|Homo sapiens Anion exchanger 2 type ...   612   e-174
BC028601-1|AAH28601.1| 1159|Homo sapiens SLC4A2 protein protein.      610   e-174
L27213-1|AAB05850.1|  932|Homo sapiens anion exchange protein pr...   601   e-171
X62137-1|CAA44067.1| 1240|Homo sapiens anion exchange protein 2 ...   591   e-168
X03918-1|CAA27556.1|  865|Homo sapiens HKB3 (865 aa) protein.         591   e-168
X12609-1|CAA31128.1|  911|Homo sapiens protein ( H.sapiens mRNA ...   530   e-149
M27819-1|AAA35514.1|  911|Homo sapiens protein ( Human anion exc...   530   e-149
DQ072115-1|AAY57324.1|  911|Homo sapiens solute carrier family 4...   530   e-149
BC101574-1|AAI01575.1|  911|Homo sapiens solute carrier family 4...   530   e-149
BC101570-1|AAI01571.1|  911|Homo sapiens solute carrier family 4...   530   e-149
BC099629-1|AAH99629.1|  911|Homo sapiens solute carrier family 4...   530   e-149
BC099628-1|AAH99628.1|  911|Homo sapiens solute carrier family 4...   530   e-149
BC096107-1|AAH96107.1|  911|Homo sapiens solute carrier family 4...   530   e-149
BC096106-1|AAH96106.1|  911|Homo sapiens solute carrier family 4...   530   e-149
DQ419529-1|ABD74692.1|  911|Homo sapiens solute carrier family 4...   528   e-149
EF531618-1|ABQ43327.1| 1094|Homo sapiens solute carrier family 4...   474   e-133
AF310248-1|AAG47773.1| 1079|Homo sapiens sodium bicarbonate cotr...   474   e-133
AF069510-1|AAD42020.1| 1079|Homo sapiens sodium bicarbonate cotr...   474   e-133
AF011390-1|AAC39840.1| 1079|Homo sapiens pancreas sodium bicarbo...   474   e-133
AF007216-1|AAC51645.1| 1035|Homo sapiens sodium bicarbonate cotr...   474   e-133
AF053754-1|AAF21719.1| 1079|Homo sapiens electrogenic Na+ bicarb...   473   e-132
AF053753-1|AAF21718.1| 1079|Homo sapiens electrogenic Na+ bicarb...   469   e-131
AF293337-1|AAK97072.1| 1121|Homo sapiens sodium bicarbonate cotr...   430   e-119
AF452248-1|AAL48291.1| 1051|Homo sapiens sodium bicarbonate cotr...   425   e-118
AF243499-1|AAK26741.1| 1137|Homo sapiens sodium bicarbonate cotr...   411   e-114
AF332961-1|AAK69625.1|  959|Homo sapiens anion exchanger AE4 pro...   404   e-112
AF313465-1|AAK28832.1|  990|Homo sapiens sodium bicarbonate cotr...   404   e-112
AB032762-1|BAA93010.1|  957|Homo sapiens sodium bicarbonate cotr...   404   e-112
AF207661-1|AAG18492.1| 1074|Homo sapiens sodium bicarbonate cotr...   403   e-111
BC109221-1|AAI09222.1| 1019|Homo sapiens SLC4A5 protein protein.      399   e-110
AF336237-1|AAK16733.1|  945|Homo sapiens anion exchanger AE4 pro...   375   e-103
AF293338-1|AAK97073.1| 1040|Homo sapiens sodium bicarbonate cotr...   336   2e-91
AF157492-1|AAF80343.1|  995|Homo sapiens sodium bicarbonate cotr...   303   2e-81
AC073263-6|AAX93062.1|  714|Homo sapiens unknown protein.             299   3e-80
BC030977-1|AAH30977.1|  646|Homo sapiens SLC4A4 protein protein.      273   2e-72
AF004813-1|AAD31379.1|  670|Homo sapiens electrogenic Na+ bicarb...   273   2e-72
AF089726-1|AAG16773.1| 1090|Homo sapiens sodium bicarbonate cotr...   270   1e-71
AF047033-1|AAD38322.1| 1214|Homo sapiens sodium bicarbonate cotr...   270   1e-71
AB012130-1|BAA25898.1| 1018|Homo sapiens sodium bicarbonate cotr...   270   1e-71
AF053755-1|AAF21720.1| 1000|Homo sapiens bicarbonate transporter...   268   7e-71
AB209752-1|BAD92989.1|  906|Homo sapiens sodium bicarbonate tran...   258   5e-68
AY376402-1|AAQ83632.1| 1118|Homo sapiens solute carrier family 4...   258   8e-68
AB040457-1|BAB18301.1| 1088|Homo sapiens NCBE protein.                256   2e-67
DQ996537-1|ABJ91576.1|  991|Homo sapiens sodium bicarbonate cotr...   252   4e-66
DQ996398-1|ABJ91577.1|  991|Homo sapiens sodium bicarbonate cotr...   252   4e-66
DQ975204-1|ABJ09587.1| 1040|Homo sapiens sodium-driven chloride ...   252   4e-66
DQ063579-1|AAY79176.1| 1093|Homo sapiens Na+-driven Cl-HCO3 exch...   252   4e-66
BC025994-1|AAH25994.1|  691|Homo sapiens SLC4A8 protein protein.      252   4e-66
AF107099-1|AAD52981.1|  670|Homo sapiens sodium bicarbonate cotr...   252   4e-66
AF069512-1|AAC82380.1| 1044|Homo sapiens sodium bicarbonate cotr...   252   4e-66
AB018282-1|BAA34459.1| 1130|Homo sapiens KIAA0739 protein protein.    252   4e-66
AF453528-1|AAL50802.1|  760|Homo sapiens sodium bicarbonate cotr...   244   1e-63
X87211-1|CAA60670.1|  357|Homo sapiens anion exchange protein pr...   241   6e-63
X70797-1|CAA50067.1|  357|Homo sapiens anion exchange protein 3 ...   241   6e-63
AL109976-2|CAB90170.4|  918|Homo sapiens solute carrier family 4...   189   3e-47
AL109976-1|CAD55941.1|  891|Homo sapiens solute carrier family 4...   189   3e-47
AK075303-1|BAC11536.1|  633|Homo sapiens protein ( Homo sapiens ...   189   3e-47
AF336127-1|AAK16734.1|  891|Homo sapiens bicarbonate transporter...   189   3e-47
BC110540-1|AAI10541.1|  891|Homo sapiens solute carrier family 4...   187   2e-46
BC110541-1|AAI10542.1|  409|Homo sapiens SLC4A11 protein protein.     124   1e-27
AK128321-1|BAC87383.1|  329|Homo sapiens ember 8 (SLC4A8).  prot...    96   5e-19
AC103915-1|AAY14938.1|   80|Homo sapiens unknown protein.              84   2e-15
AC006030-1|AAF03523.2|  341|Homo sapiens unknown protein.              64   2e-09
AF226050-1|AAF86950.1|  319|Homo sapiens HCDI protein.                 33   5.7  
BC017710-1|AAH17710.1|  423|Homo sapiens zinc finger protein 271...    32   7.5  
BC004510-1|AAH04510.2|  272|Homo sapiens ZNF271 protein protein.       32   7.5  
AF159567-1|AAD43569.1|  423|Homo sapiens epstein-barr virus-indu...    32   7.5  
AF153201-1|AAD38056.1|  423|Homo sapiens zinc finger protein dp ...    32   7.5  
BC104759-1|AAI04760.1|  571|Homo sapiens ZNF181 protein protein.       32   9.9  
BC043228-1|AAH43228.1|  507|Homo sapiens zinc finger protein 181...    32   9.9  

>AY142112-1|AAN34939.1| 1259|Homo sapiens anion exchanger SLC4A3
            protein.
          Length = 1259

 Score =  627 bits (1548), Expect = e-179
 Identities = 341/769 (44%), Positives = 479/769 (62%), Gaps = 50/769 (6%)

Query: 92   ILKRIPDDAEATTVLVGAVGFLDQPTIAFVRLAEGIYMPSITEVPVPVRFMFILLGPGGA 151
            +L++IP+DAEAT VLVG V FL+QP  AFVRL E + + S+ EVPVPVRF+F++LGP   
Sbjct: 532  LLEKIPEDAEATVVLVGCVPFLEQPAAAFVRLNEAVLLESVLEVPVPVRFLFVMLGPSHT 591

Query: 152  DLDYHEVGRSISTLMSNPAFHSIAYKADDRRELLSAINEFLDDSIVLPPGDWERQALLPL 211
              DYHE+GRSI+TLMS+  FH  AYKADDR++LLSAI+EFLD SIV+PP + E + LL  
Sbjct: 592  STDYHELGRSIATLMSDKLFHEAAYKADDRQDLLSAISEFLDGSIVIPPSEVEGRDLLR- 650

Query: 212  EELRAKSEMIRRRKINALERKRIVADGDKPSDEKKALLAAEAGGMPPEEPDDPLSRTGRL 271
                 + E++R+R+     +  +   G   +  K+  L+ E GG      DDPL RTG +
Sbjct: 651  SVAAFQRELLRKRREREQTKVEMTTRGGYTAPGKE--LSLELGGSEATPEDDPLLRTGSV 708

Query: 272  FGGVIRDMKRRYPFYVSDFVDALNGQCVAATIFMYFAAVSSAITFGGLLAEKTYGKIGIS 331
            FGG++RD++RRYP Y SD  DAL+ QCVAA +F+YFAA+S AITFGGLL EKT G +G+S
Sbjct: 709  FGGLVRDVRRRYPHYPSDLRDALHSQCVAAVLFIYFAALSPAITFGGLLGEKTEGLMGVS 768

Query: 332  ETLSSGYVRSAVEGDLQVFTSAGGVLFALVAGQPMMITGATGPLLLLDESLANFCHSYGF 391
            E + S              T+  GVLF+L+  QP+++ G +GPLL+ +E+   FC +   
Sbjct: 769  ELIVS--------------TAVLGVLFSLLGAQPLLVVGFSGPLLVFEEAFFKFCRAQDL 814

Query: 392  DFLAARMYCGLWMIVIALCVASVEGSVAVKKITRFTEDXXXXXXXXXXXXEPITSTIAVY 451
            ++L  R++ GLW++V  L + + EGS  V+ I+ FT++            E       V+
Sbjct: 815  EYLTGRVWVGLWLVVFVLALVAAEGSFLVRYISPFTQEIFAFLISLIFIYETFYKLYKVF 874

Query: 452  RANPLGIDYCQFREVALSNSTVQPLLNSTSVGNSSVVAPA--PPVSRLPPQPNTALFCTM 509
               PL   Y    E AL  S     L++    N S + P   PP  R   QPNTAL   +
Sbjct: 875  TERPLLPFYPP--EGALEGS-----LDAGLEPNGSALPPTEGPPSPR--NQPNTALLSLI 925

Query: 510  LTLATFVLAYYLRIFRNGKFLGRSSATSRVQVTGRDGIQARRALGDFGVPIAIVLMVGIS 569
            L L TF +A++LR FRN +FLG                +ARR +GDFG+PI+I++MV + 
Sbjct: 926  LMLGTFFIAFFLRKFRNSRFLGG---------------KARRIIGDFGIPISILVMVLVD 970

Query: 570  -CLVPVKTETLVVPAGLNPTTV--RSWFVPLNPGLETIXXXXXXXXXXXXXXVYIIVFME 626
              +    T+ L VP GL+ T+   RSWF+P                      V I++FME
Sbjct: 971  YSITDTYTQKLTVPTGLSVTSPDKRSWFIPPLGSARPFPPWMMVAAAVPALLVLILIFME 1030

Query: 627  THIAELIIAKPERRLKKGSGFHMDIVIMSFVNALCGMFGAPWQCVATVRSVSHVSALTIM 686
            T I  LI+++  RRL KGSGFH+D++++  +  LCG+FG PW   ATVRS++HV+ALT+M
Sbjct: 1031 TQITALIVSQKARRLLKGSGFHLDLLLIGSLGGLCGLFGLPWLTAATVRSITHVNALTVM 1090

Query: 687  STTHAPGDKPHIVEVKEQRLTGLLVAVMVGISVLASGWLCLVPMAVLFGVFLYMGISALG 746
             T  APGDKP I EV+EQR+TG+L+A +VG+S++    L  +P+AVLFG+FLYMG+++L 
Sbjct: 1091 RTAIAPGDKPQIQEVREQRVTGVLIASLVGLSIVMGAVLRRIPLAVLFGIFLYMGVTSLS 1150

Query: 747  GIQFWDRCILLLKPVKHHPQLPYVRRVPTLKMHMYTLIQVGGVVVLYAVKSSRFSLALPF 806
            GIQ   R +L+L P KHHP+ PYV +V T +MH++T IQ+G + +L+ VKS+  SLA PF
Sbjct: 1151 GIQLSQRLLLILMPAKHHPEQPYVTKVKTWRMHLFTCIQLGCIALLWVVKSTAASLAFPF 1210

Query: 807  FLVLMVPLRMSLV-YIFTPLQLRALDG--AQKDIDKDDEPDFYEEAPIP 852
             L+L VPLR  L+  +F   +L+ALD   A+ + D+D + D Y E  +P
Sbjct: 1211 LLLLTVPLRHCLLPRLFQDRELQALDSEDAEPNFDEDGQ-DEYNELHMP 1258


>U05596-1|AAA50748.1| 1232|Homo sapiens anion exchanger 3 brain
            isoform protein.
          Length = 1232

 Score =  625 bits (1545), Expect = e-178
 Identities = 339/767 (44%), Positives = 478/767 (62%), Gaps = 46/767 (5%)

Query: 92   ILKRIPDDAEATTVLVGAVGFLDQPTIAFVRLAEGIYMPSITEVPVPVRFMFILLGPGGA 151
            +L++IP+DAEAT VLVG V FL+QP  AFVRL E + + S+ EVPVPVRF+F++LGP   
Sbjct: 505  LLEKIPEDAEATVVLVGCVPFLEQPAAAFVRLNEAVLLESVLEVPVPVRFLFVMLGPSHT 564

Query: 152  DLDYHEVGRSISTLMSNPAFHSIAYKADDRRELLSAINEFLDDSIVLPPGDWERQALLPL 211
              DYHE+GRSI+TLMS+  FH  AY+ADDR++LLSAI+EFLD SIV+PP + E + LL  
Sbjct: 565  STDYHELGRSIATLMSDKLFHEAAYQADDRQDLLSAISEFLDGSIVIPPSEVEGRDLLR- 623

Query: 212  EELRAKSEMIRRRKINALERKRIVADGDKPSDEKKALLAAEAGGMPPEEPDDPLSRTGRL 271
                 + E++R+R+     +  +   G   +  K+  L+ E GG      DDPL RTG +
Sbjct: 624  SVAAFQRELLRKRREREQTKVEMTTRGGYTAPGKE--LSLELGGSEATPEDDPLLRTGSV 681

Query: 272  FGGVIRDMKRRYPFYVSDFVDALNGQCVAATIFMYFAAVSSAITFGGLLAEKTYGKIGIS 331
            FGG++RD++RRYP Y SD  DAL+ QCVAA +F+YFAA+S AITFGGLL EKT G +G+S
Sbjct: 682  FGGLVRDVRRRYPHYPSDLRDALHSQCVAAVLFIYFAALSPAITFGGLLGEKTEGLMGVS 741

Query: 332  ETLSSGYVRSAVEGDLQVFTSAGGVLFALVAGQPMMITGATGPLLLLDESLANFCHSYGF 391
            E + S              T+  GVLF+L+  QP+++ G +GPLL+ +E+   FC +   
Sbjct: 742  ELIVS--------------TAVLGVLFSLLGAQPLLVVGFSGPLLVFEEAFFKFCRAQDL 787

Query: 392  DFLAARMYCGLWMIVIALCVASVEGSVAVKKITRFTEDXXXXXXXXXXXXEPITSTIAVY 451
            ++L  R++ GLW++V  L + + EGS  V+ I+ FT++            E       V+
Sbjct: 788  EYLTGRVWVGLWLVVFVLALVAAEGSFLVRYISPFTQEIFAFLISLIFIYETFYKLYKVF 847

Query: 452  RANPLGIDYCQFREVALSNSTVQPLLNSTSVGNSSVVAPAPPVSRLPPQPNTALFCTMLT 511
              +PL   Y    E AL  S    L  +   G++      PP  R   QPNTAL   +L 
Sbjct: 848  TEHPLLPFYPP--EGALEGSLAAGLEPN---GSALPPTEGPPSPR--NQPNTALLSLILM 900

Query: 512  LATFVLAYYLRIFRNGKFLGRSSATSRVQVTGRDGIQARRALGDFGVPIAIVLMVGIS-C 570
            L TF +A++LR FRN +FLG                +ARR +GDFG+PI+I++MV +   
Sbjct: 901  LGTFFIAFFLRKFRNSRFLGG---------------KARRIIGDFGIPISILVMVLVDYS 945

Query: 571  LVPVKTETLVVPAGLNPTTV--RSWFVPLNPGLETIXXXXXXXXXXXXXXVYIIVFMETH 628
            +    T+ L VP GL+ T+   RSWF+P                      V I++FMET 
Sbjct: 946  ITDTYTQKLTVPTGLSVTSPDKRSWFIPPLGSARPFPPWMMVAAAVPALLVLILIFMETQ 1005

Query: 629  IAELIIAKPERRLKKGSGFHMDIVIMSFVNALCGMFGAPWQCVATVRSVSHVSALTIMST 688
            I  LI+++  RRL KGSGFH+D++++  +  LCG+FG PW   ATVRSV+HV+ALT+M T
Sbjct: 1006 ITALIVSQKARRLLKGSGFHLDLLLIGSLGGLCGLFGLPWLTAATVRSVTHVNALTVMRT 1065

Query: 689  THAPGDKPHIVEVKEQRLTGLLVAVMVGISVLASGWLCLVPMAVLFGVFLYMGISALGGI 748
              APGDKP I EV+EQR+TG+L+A +VG+S++    L  +P+AVLFG+FLYMG+++L GI
Sbjct: 1066 AIAPGDKPQIQEVREQRVTGVLIASLVGLSIVMGAVLRRIPLAVLFGIFLYMGVTSLSGI 1125

Query: 749  QFWDRCILLLKPVKHHPQLPYVRRVPTLKMHMYTLIQVGGVVVLYAVKSSRFSLALPFFL 808
            Q   R +L+L P KHHP+ PYV +V T +MH++T IQ+G + +L+ VKS+  SLA PF L
Sbjct: 1126 QLSQRLLLILMPAKHHPEQPYVTKVKTWRMHLFTCIQLGCIALLWVVKSTAASLAFPFLL 1185

Query: 809  VLMVPLRMSLV-YIFTPLQLRALDG--AQKDIDKDDEPDFYEEAPIP 852
            +L VPLR  L+  +F   +L+ALD   A+ + D+D + D Y E  +P
Sbjct: 1186 LLTVPLRHCLLPRLFQDRELQALDSEDAEPNFDEDGQ-DEYNELHMP 1231


>U76669-3|AAF19584.2| 1227|Homo sapiens anion exchanger 2 type b1
            protein.
          Length = 1227

 Score =  612 bits (1511), Expect = e-174
 Identities = 337/777 (43%), Positives = 482/777 (62%), Gaps = 50/777 (6%)

Query: 88   HNDSILKRIPDDAEATTVLVGAVGFLDQPTIAFVRLAEGIYMPSITEVPVPVRFMFILLG 147
            H   +L++IP++AEAT VLVG V FL +PT+AFVRL E + + ++ EVPVPVRF+F+LLG
Sbjct: 488  HELKLLEKIPENAEATVVLVGCVEFLSRPTMAFVRLREAVELDAVLEVPVPVRFLFLLLG 547

Query: 148  PGGADLDYHEVGRSISTLMSNPAFHSIAYKADDRRELLSAINEFLDDSIVLPPGDWERQA 207
            P  A++DYHE+GRSISTLMS+  FH  AY AD+R +LL+AIN FLD S+VLPP + + + 
Sbjct: 548  PSSANMDYHEIGRSISTLMSDKQFHEAAYLADEREDLLTAINAFLDCSVVLPPSEVQGEE 607

Query: 208  LLPLEELRAKSEMIRRRKINALERKRIVADG----DKPSDEKKALLAAEAGGMPPEEPDD 263
            LL       + +M+++R+    E+ R++  G     K + +K  L   EA G      DD
Sbjct: 608  LLR-SVAHFQRQMLKKRE----EQGRLLPTGAGLEPKSAQDKALLQMVEAAGAAE---DD 659

Query: 264  PLSRTGRLFGGVIRDMKRRYPFYVSDFVDALNGQCVAATIFMYFAAVSSAITFGGLLAEK 323
            PL RTGR FGG+IRD++RRYP Y+SDF DAL+ QC+AA IF+YFAA+S AITFGGLL EK
Sbjct: 660  PLRRTGRPFGGLIRDVRRRYPHYLSDFRDALDPQCLAAVIFIYFAALSPAITFGGLLGEK 719

Query: 324  TYGKIGISETLSSGYVRSAVEGDLQVFTSAGGVLFALVAGQPMMITGATGPLLLLDESLA 383
            T   IG+SE + S              T+  GV+F L+  QP+++ G +GPLL+ +E+  
Sbjct: 720  TQDLIGVSELIMS--------------TALQGVVFCLLGAQPLLVIGFSGPLLVFEEAFF 765

Query: 384  NFCHSYGFDFLAARMYCGLWMIVIALCVASVEGSVAVKKITRFTEDXXXXXXXXXXXXEP 443
            +FC S   ++L  R++ G W++ +AL + ++EGS  V+ ++RFT++            E 
Sbjct: 766  SFCSSNHLEYLVGRVWIGFWLVFLALLMVALEGSFLVRFVSRFTQEIFAFLISLIFIYET 825

Query: 444  ITSTIAVYRANPL-GIDYCQFREV-ALSNSTVQPLLNSTSVGNSSVVAPAPPVSRLPPQP 501
                + +++ +PL G       EV    N T      +   GN S+   +    +   QP
Sbjct: 826  FYKLVKIFQEHPLHGCSASNSSEVDGGENMTWAGARPTLGPGNRSLAGQSGQ-GKPRGQP 884

Query: 502  NTALFCTMLTLATFVLAYYLRIFRNGKFLGRSSATSRVQVTGRDGIQARRALGDFGVPIA 561
            NTAL   +L   TF +A++LR F+N +F             GR     RR +GDFGVPIA
Sbjct: 885  NTALLSLVLMAGTFFIAFFLRKFKNSRFF-----------PGR----IRRVIGDFGVPIA 929

Query: 562  IVLMVGISCLVP-VKTETLVVPAGLNPTTV--RSWFVPLNPGLETIXXXXXXXXXXXXXX 618
            I++MV +   +    T+ L VP+G + T    R W +                       
Sbjct: 930  ILIMVLVDYSIEDTYTQKLSVPSGFSVTAPEKRGWVINPLGEKSPFPVWMMVASLLPAIL 989

Query: 619  VYIIVFMETHIAELIIAKPERRLKKGSGFHMDIVIMSFVNALCGMFGAPWQCVATVRSVS 678
            V+I++FMET I  LII+K ER L+KGSGFH+D++++  +  +C +FG PW   ATVRSV+
Sbjct: 990  VFILIFMETQITTLIISKKERMLQKGSGFHLDLLLIVAMGGICALFGLPWLAAATVRSVT 1049

Query: 679  HVSALTIMSTTHAPGDKPHIVEVKEQRLTGLLVAVMVGISVLASGWLCLVPMAVLFGVFL 738
            H +ALT+MS   APGDKP I EVKEQR+TGLLVA++VG+S++    L  +P+AVLFG+FL
Sbjct: 1050 HANALTVMSKAVAPGDKPKIQEVKEQRVTGLLVALLVGLSIVIGDLLRQIPLAVLFGIFL 1109

Query: 739  YMGISALGGIQFWDRCILLLKPVKHHPQLPYVRRVPTLKMHMYTLIQVGGVVVLYAVKSS 798
            YMG+++L GIQF++R  LLL P KHHP + YV++V TL+MH++T +Q+  + +L+AV S+
Sbjct: 1110 YMGVTSLNGIQFYERLHLLLMPPKHHPDVTYVKKVRTLRMHLFTALQLLCLALLWAVMST 1169

Query: 799  RFSLALPFFLVLMVPLRM-SLVYIFTPLQLRALDG--AQKDIDKDDEPDFYEEAPIP 852
              SLA PF L+L VPLRM  L  IFT  +++ LD   A+   D+ +  D Y E P+P
Sbjct: 1170 AASLAFPFILILTVPLRMVVLTRIFTDREMKCLDANEAEPVFDEREGVDEYNEMPMP 1226


>U76669-2|AAF23240.1| 1232|Homo sapiens anion exchanger 2 type b2
            protein.
          Length = 1232

 Score =  612 bits (1511), Expect = e-174
 Identities = 337/777 (43%), Positives = 482/777 (62%), Gaps = 50/777 (6%)

Query: 88   HNDSILKRIPDDAEATTVLVGAVGFLDQPTIAFVRLAEGIYMPSITEVPVPVRFMFILLG 147
            H   +L++IP++AEAT VLVG V FL +PT+AFVRL E + + ++ EVPVPVRF+F+LLG
Sbjct: 493  HELKLLEKIPENAEATVVLVGCVEFLSRPTMAFVRLREAVELDAVLEVPVPVRFLFLLLG 552

Query: 148  PGGADLDYHEVGRSISTLMSNPAFHSIAYKADDRRELLSAINEFLDDSIVLPPGDWERQA 207
            P  A++DYHE+GRSISTLMS+  FH  AY AD+R +LL+AIN FLD S+VLPP + + + 
Sbjct: 553  PSSANMDYHEIGRSISTLMSDKQFHEAAYLADEREDLLTAINAFLDCSVVLPPSEVQGEE 612

Query: 208  LLPLEELRAKSEMIRRRKINALERKRIVADG----DKPSDEKKALLAAEAGGMPPEEPDD 263
            LL       + +M+++R+    E+ R++  G     K + +K  L   EA G      DD
Sbjct: 613  LLR-SVAHFQRQMLKKRE----EQGRLLPTGAGLEPKSAQDKALLQMVEAAGAAE---DD 664

Query: 264  PLSRTGRLFGGVIRDMKRRYPFYVSDFVDALNGQCVAATIFMYFAAVSSAITFGGLLAEK 323
            PL RTGR FGG+IRD++RRYP Y+SDF DAL+ QC+AA IF+YFAA+S AITFGGLL EK
Sbjct: 665  PLRRTGRPFGGLIRDVRRRYPHYLSDFRDALDPQCLAAVIFIYFAALSPAITFGGLLGEK 724

Query: 324  TYGKIGISETLSSGYVRSAVEGDLQVFTSAGGVLFALVAGQPMMITGATGPLLLLDESLA 383
            T   IG+SE + S              T+  GV+F L+  QP+++ G +GPLL+ +E+  
Sbjct: 725  TQDLIGVSELIMS--------------TALQGVVFCLLGAQPLLVIGFSGPLLVFEEAFF 770

Query: 384  NFCHSYGFDFLAARMYCGLWMIVIALCVASVEGSVAVKKITRFTEDXXXXXXXXXXXXEP 443
            +FC S   ++L  R++ G W++ +AL + ++EGS  V+ ++RFT++            E 
Sbjct: 771  SFCSSNHLEYLVGRVWIGFWLVFLALLMVALEGSFLVRFVSRFTQEIFAFLISLIFIYET 830

Query: 444  ITSTIAVYRANPL-GIDYCQFREV-ALSNSTVQPLLNSTSVGNSSVVAPAPPVSRLPPQP 501
                + +++ +PL G       EV    N T      +   GN S+   +    +   QP
Sbjct: 831  FYKLVKIFQEHPLHGCSASNSSEVDGGENMTWAGARPTLGPGNRSLAGQSGQ-GKPRGQP 889

Query: 502  NTALFCTMLTLATFVLAYYLRIFRNGKFLGRSSATSRVQVTGRDGIQARRALGDFGVPIA 561
            NTAL   +L   TF +A++LR F+N +F             GR     RR +GDFGVPIA
Sbjct: 890  NTALLSLVLMAGTFFIAFFLRKFKNSRFF-----------PGR----IRRVIGDFGVPIA 934

Query: 562  IVLMVGISCLVP-VKTETLVVPAGLNPTTV--RSWFVPLNPGLETIXXXXXXXXXXXXXX 618
            I++MV +   +    T+ L VP+G + T    R W +                       
Sbjct: 935  ILIMVLVDYSIEDTYTQKLSVPSGFSVTAPEKRGWVINPLGEKSPFPVWMMVASLLPAIL 994

Query: 619  VYIIVFMETHIAELIIAKPERRLKKGSGFHMDIVIMSFVNALCGMFGAPWQCVATVRSVS 678
            V+I++FMET I  LII+K ER L+KGSGFH+D++++  +  +C +FG PW   ATVRSV+
Sbjct: 995  VFILIFMETQITTLIISKKERMLQKGSGFHLDLLLIVAMGGICALFGLPWLAAATVRSVT 1054

Query: 679  HVSALTIMSTTHAPGDKPHIVEVKEQRLTGLLVAVMVGISVLASGWLCLVPMAVLFGVFL 738
            H +ALT+MS   APGDKP I EVKEQR+TGLLVA++VG+S++    L  +P+AVLFG+FL
Sbjct: 1055 HANALTVMSKAVAPGDKPKIQEVKEQRVTGLLVALLVGLSIVIGDLLRQIPLAVLFGIFL 1114

Query: 739  YMGISALGGIQFWDRCILLLKPVKHHPQLPYVRRVPTLKMHMYTLIQVGGVVVLYAVKSS 798
            YMG+++L GIQF++R  LLL P KHHP + YV++V TL+MH++T +Q+  + +L+AV S+
Sbjct: 1115 YMGVTSLNGIQFYERLHLLLMPPKHHPDVTYVKKVRTLRMHLFTALQLLCLALLWAVMST 1174

Query: 799  RFSLALPFFLVLMVPLRM-SLVYIFTPLQLRALDG--AQKDIDKDDEPDFYEEAPIP 852
              SLA PF L+L VPLRM  L  IFT  +++ LD   A+   D+ +  D Y E P+P
Sbjct: 1175 AASLAFPFILILTVPLRMVVLTRIFTDREMKCLDANEAEPVFDEREGVDEYNEMPMP 1231


>U76669-1|AAF19583.2| 1241|Homo sapiens anion exchanger 2 type a
            protein.
          Length = 1241

 Score =  612 bits (1511), Expect = e-174
 Identities = 337/777 (43%), Positives = 482/777 (62%), Gaps = 50/777 (6%)

Query: 88   HNDSILKRIPDDAEATTVLVGAVGFLDQPTIAFVRLAEGIYMPSITEVPVPVRFMFILLG 147
            H   +L++IP++AEAT VLVG V FL +PT+AFVRL E + + ++ EVPVPVRF+F+LLG
Sbjct: 502  HELKLLEKIPENAEATVVLVGCVEFLSRPTMAFVRLREAVELDAVLEVPVPVRFLFLLLG 561

Query: 148  PGGADLDYHEVGRSISTLMSNPAFHSIAYKADDRRELLSAINEFLDDSIVLPPGDWERQA 207
            P  A++DYHE+GRSISTLMS+  FH  AY AD+R +LL+AIN FLD S+VLPP + + + 
Sbjct: 562  PSSANMDYHEIGRSISTLMSDKQFHEAAYLADEREDLLTAINAFLDCSVVLPPSEVQGEE 621

Query: 208  LLPLEELRAKSEMIRRRKINALERKRIVADG----DKPSDEKKALLAAEAGGMPPEEPDD 263
            LL       + +M+++R+    E+ R++  G     K + +K  L   EA G      DD
Sbjct: 622  LLR-SVAHFQRQMLKKRE----EQGRLLPTGAGLEPKSAQDKALLQMVEAAGAAE---DD 673

Query: 264  PLSRTGRLFGGVIRDMKRRYPFYVSDFVDALNGQCVAATIFMYFAAVSSAITFGGLLAEK 323
            PL RTGR FGG+IRD++RRYP Y+SDF DAL+ QC+AA IF+YFAA+S AITFGGLL EK
Sbjct: 674  PLRRTGRPFGGLIRDVRRRYPHYLSDFRDALDPQCLAAVIFIYFAALSPAITFGGLLGEK 733

Query: 324  TYGKIGISETLSSGYVRSAVEGDLQVFTSAGGVLFALVAGQPMMITGATGPLLLLDESLA 383
            T   IG+SE + S              T+  GV+F L+  QP+++ G +GPLL+ +E+  
Sbjct: 734  TQDLIGVSELIMS--------------TALQGVVFCLLGAQPLLVIGFSGPLLVFEEAFF 779

Query: 384  NFCHSYGFDFLAARMYCGLWMIVIALCVASVEGSVAVKKITRFTEDXXXXXXXXXXXXEP 443
            +FC S   ++L  R++ G W++ +AL + ++EGS  V+ ++RFT++            E 
Sbjct: 780  SFCSSNHLEYLVGRVWIGFWLVFLALLMVALEGSFLVRFVSRFTQEIFAFLISLIFIYET 839

Query: 444  ITSTIAVYRANPL-GIDYCQFREV-ALSNSTVQPLLNSTSVGNSSVVAPAPPVSRLPPQP 501
                + +++ +PL G       EV    N T      +   GN S+   +    +   QP
Sbjct: 840  FYKLVKIFQEHPLHGCSASNSSEVDGGENMTWAGARPTLGPGNRSLAGQSGQ-GKPRGQP 898

Query: 502  NTALFCTMLTLATFVLAYYLRIFRNGKFLGRSSATSRVQVTGRDGIQARRALGDFGVPIA 561
            NTAL   +L   TF +A++LR F+N +F             GR     RR +GDFGVPIA
Sbjct: 899  NTALLSLVLMAGTFFIAFFLRKFKNSRFF-----------PGR----IRRVIGDFGVPIA 943

Query: 562  IVLMVGISCLVP-VKTETLVVPAGLNPTTV--RSWFVPLNPGLETIXXXXXXXXXXXXXX 618
            I++MV +   +    T+ L VP+G + T    R W +                       
Sbjct: 944  ILIMVLVDYSIEDTYTQKLSVPSGFSVTAPEKRGWVINPLGEKSPFPVWMMVASLLPAIL 1003

Query: 619  VYIIVFMETHIAELIIAKPERRLKKGSGFHMDIVIMSFVNALCGMFGAPWQCVATVRSVS 678
            V+I++FMET I  LII+K ER L+KGSGFH+D++++  +  +C +FG PW   ATVRSV+
Sbjct: 1004 VFILIFMETQITTLIISKKERMLQKGSGFHLDLLLIVAMGGICALFGLPWLAAATVRSVT 1063

Query: 679  HVSALTIMSTTHAPGDKPHIVEVKEQRLTGLLVAVMVGISVLASGWLCLVPMAVLFGVFL 738
            H +ALT+MS   APGDKP I EVKEQR+TGLLVA++VG+S++    L  +P+AVLFG+FL
Sbjct: 1064 HANALTVMSKAVAPGDKPKIQEVKEQRVTGLLVALLVGLSIVIGDLLRQIPLAVLFGIFL 1123

Query: 739  YMGISALGGIQFWDRCILLLKPVKHHPQLPYVRRVPTLKMHMYTLIQVGGVVVLYAVKSS 798
            YMG+++L GIQF++R  LLL P KHHP + YV++V TL+MH++T +Q+  + +L+AV S+
Sbjct: 1124 YMGVTSLNGIQFYERLHLLLMPPKHHPDVTYVKKVRTLRMHLFTALQLLCLALLWAVMST 1183

Query: 799  RFSLALPFFLVLMVPLRM-SLVYIFTPLQLRALDG--AQKDIDKDDEPDFYEEAPIP 852
              SLA PF L+L VPLRM  L  IFT  +++ LD   A+   D+ +  D Y E P+P
Sbjct: 1184 AASLAFPFILILTVPLRMVVLTRIFTDREMKCLDANEAEPVFDEREGVDEYNEMPMP 1240


>U62531-1|AAC50964.1| 1241|Homo sapiens AE2 anion exchanger protein.
          Length = 1241

 Score =  612 bits (1511), Expect = e-174
 Identities = 337/777 (43%), Positives = 482/777 (62%), Gaps = 50/777 (6%)

Query: 88   HNDSILKRIPDDAEATTVLVGAVGFLDQPTIAFVRLAEGIYMPSITEVPVPVRFMFILLG 147
            H   +L++IP++AEAT VLVG V FL +PT+AFVRL E + + ++ EVPVPVRF+F+LLG
Sbjct: 502  HELKLLEKIPENAEATVVLVGCVEFLSRPTMAFVRLREAVELDAVLEVPVPVRFLFLLLG 561

Query: 148  PGGADLDYHEVGRSISTLMSNPAFHSIAYKADDRRELLSAINEFLDDSIVLPPGDWERQA 207
            P  A++DYHE+GRSISTLMS+  FH  AY AD+R +LL+AIN FLD S+VLPP + + + 
Sbjct: 562  PSSANMDYHEIGRSISTLMSDKQFHEAAYLADEREDLLTAINAFLDCSVVLPPSEVQGEE 621

Query: 208  LLPLEELRAKSEMIRRRKINALERKRIVADG----DKPSDEKKALLAAEAGGMPPEEPDD 263
            LL       + +M+++R+    E+ R++  G     K + +K  L   EA G      DD
Sbjct: 622  LLR-SVAHFQRQMLKKRE----EQGRLLPTGAGLEPKSAQDKALLQMVEAAGAAE---DD 673

Query: 264  PLSRTGRLFGGVIRDMKRRYPFYVSDFVDALNGQCVAATIFMYFAAVSSAITFGGLLAEK 323
            PL RTGR FGG+IRD++RRYP Y+SDF DAL+ QC+AA IF+YFAA+S AITFGGLL EK
Sbjct: 674  PLRRTGRPFGGLIRDVRRRYPHYLSDFRDALDPQCLAAVIFIYFAALSPAITFGGLLGEK 733

Query: 324  TYGKIGISETLSSGYVRSAVEGDLQVFTSAGGVLFALVAGQPMMITGATGPLLLLDESLA 383
            T   IG+SE + S              T+  GV+F L+  QP+++ G +GPLL+ +E+  
Sbjct: 734  TQDLIGVSELIMS--------------TALQGVVFCLLGAQPLLVIGFSGPLLVFEEAFF 779

Query: 384  NFCHSYGFDFLAARMYCGLWMIVIALCVASVEGSVAVKKITRFTEDXXXXXXXXXXXXEP 443
            +FC S   ++L  R++ G W++ +AL + ++EGS  V+ ++RFT++            E 
Sbjct: 780  SFCSSNHLEYLVGRVWIGFWLVFLALLMVALEGSFLVRFVSRFTQEIFAFLISLIFIYET 839

Query: 444  ITSTIAVYRANPL-GIDYCQFREV-ALSNSTVQPLLNSTSVGNSSVVAPAPPVSRLPPQP 501
                + +++ +PL G       EV    N T      +   GN S+   +    +   QP
Sbjct: 840  FYKLVKIFQEHPLHGCSASNSSEVDGGENMTWAGARPTLGPGNRSLAGQSGQ-GKPRGQP 898

Query: 502  NTALFCTMLTLATFVLAYYLRIFRNGKFLGRSSATSRVQVTGRDGIQARRALGDFGVPIA 561
            NTAL   +L   TF +A++LR F+N +F             GR     RR +GDFGVPIA
Sbjct: 899  NTALLSLVLMAGTFFIAFFLRKFKNSRFF-----------PGR----IRRVIGDFGVPIA 943

Query: 562  IVLMVGISCLVP-VKTETLVVPAGLNPTTV--RSWFVPLNPGLETIXXXXXXXXXXXXXX 618
            I++MV +   +    T+ L VP+G + T    R W +                       
Sbjct: 944  ILIMVLVDYSIEDTYTQKLSVPSGFSVTAPEKRGWVINPLGEKSPFPVWMMVASLLPAIL 1003

Query: 619  VYIIVFMETHIAELIIAKPERRLKKGSGFHMDIVIMSFVNALCGMFGAPWQCVATVRSVS 678
            V+I++FMET I  LII+K ER L+KGSGFH+D++++  +  +C +FG PW   ATVRSV+
Sbjct: 1004 VFILIFMETQITTLIISKKERMLQKGSGFHLDLLLIVAMGGICALFGLPWLAAATVRSVT 1063

Query: 679  HVSALTIMSTTHAPGDKPHIVEVKEQRLTGLLVAVMVGISVLASGWLCLVPMAVLFGVFL 738
            H +ALT+MS   APGDKP I EVKEQR+TGLLVA++VG+S++    L  +P+AVLFG+FL
Sbjct: 1064 HANALTVMSKAVAPGDKPKIQEVKEQRVTGLLVALLVGLSIVIGDLLRQIPLAVLFGIFL 1123

Query: 739  YMGISALGGIQFWDRCILLLKPVKHHPQLPYVRRVPTLKMHMYTLIQVGGVVVLYAVKSS 798
            YMG+++L GIQF++R  LLL P KHHP + YV++V TL+MH++T +Q+  + +L+AV S+
Sbjct: 1124 YMGVTSLNGIQFYERLHLLLMPPKHHPDVTYVKKVRTLRMHLFTALQLLCLALLWAVMST 1183

Query: 799  RFSLALPFFLVLMVPLRM-SLVYIFTPLQLRALDG--AQKDIDKDDEPDFYEEAPIP 852
              SLA PF L+L VPLRM  L  IFT  +++ LD   A+   D+ +  D Y E P+P
Sbjct: 1184 AASLAFPFILILTVPLRMVVLTRIFTDREMKCLDANEAEPVFDEREGVDEYNEMPMP 1240


>DQ149844-1|AAZ38724.1| 1241|Homo sapiens solute carrier family 4,
            anion exchanger, member 2 (erythrocyte membrane protei
            protein.
          Length = 1241

 Score =  612 bits (1511), Expect = e-174
 Identities = 337/777 (43%), Positives = 482/777 (62%), Gaps = 50/777 (6%)

Query: 88   HNDSILKRIPDDAEATTVLVGAVGFLDQPTIAFVRLAEGIYMPSITEVPVPVRFMFILLG 147
            H   +L++IP++AEAT VLVG V FL +PT+AFVRL E + + ++ EVPVPVRF+F+LLG
Sbjct: 502  HELKLLEKIPENAEATVVLVGCVEFLSRPTMAFVRLREAVELDAVLEVPVPVRFLFLLLG 561

Query: 148  PGGADLDYHEVGRSISTLMSNPAFHSIAYKADDRRELLSAINEFLDDSIVLPPGDWERQA 207
            P  A++DYHE+GRSISTLMS+  FH  AY AD+R +LL+AIN FLD S+VLPP + + + 
Sbjct: 562  PSSANMDYHEIGRSISTLMSDKQFHEAAYLADEREDLLTAINAFLDCSVVLPPSEVQGEE 621

Query: 208  LLPLEELRAKSEMIRRRKINALERKRIVADG----DKPSDEKKALLAAEAGGMPPEEPDD 263
            LL       + +M+++R+    E+ R++  G     K + +K  L   EA G      DD
Sbjct: 622  LLR-SVAHFQRQMLKKRE----EQGRLLPTGAGLEPKSAQDKALLQMVEAAGAAE---DD 673

Query: 264  PLSRTGRLFGGVIRDMKRRYPFYVSDFVDALNGQCVAATIFMYFAAVSSAITFGGLLAEK 323
            PL RTGR FGG+IRD++RRYP Y+SDF DAL+ QC+AA IF+YFAA+S AITFGGLL EK
Sbjct: 674  PLRRTGRPFGGLIRDVRRRYPHYLSDFRDALDPQCLAAVIFIYFAALSPAITFGGLLGEK 733

Query: 324  TYGKIGISETLSSGYVRSAVEGDLQVFTSAGGVLFALVAGQPMMITGATGPLLLLDESLA 383
            T   IG+SE + S              T+  GV+F L+  QP+++ G +GPLL+ +E+  
Sbjct: 734  TQDLIGVSELIMS--------------TALQGVVFCLLGAQPLLVIGFSGPLLVFEEAFF 779

Query: 384  NFCHSYGFDFLAARMYCGLWMIVIALCVASVEGSVAVKKITRFTEDXXXXXXXXXXXXEP 443
            +FC S   ++L  R++ G W++ +AL + ++EGS  V+ ++RFT++            E 
Sbjct: 780  SFCSSNHLEYLVGRVWIGFWLVFLALLMVALEGSFLVRFVSRFTQEIFAFLISLIFIYET 839

Query: 444  ITSTIAVYRANPL-GIDYCQFREV-ALSNSTVQPLLNSTSVGNSSVVAPAPPVSRLPPQP 501
                + +++ +PL G       EV    N T      +   GN S+   +    +   QP
Sbjct: 840  FYKLVKIFQEHPLHGCSASNSSEVDGGENMTWAGARPTLGPGNRSLAGQSGQ-GKPRGQP 898

Query: 502  NTALFCTMLTLATFVLAYYLRIFRNGKFLGRSSATSRVQVTGRDGIQARRALGDFGVPIA 561
            NTAL   +L   TF +A++LR F+N +F             GR     RR +GDFGVPIA
Sbjct: 899  NTALLSLVLMAGTFFIAFFLRKFKNSRFF-----------PGR----IRRVIGDFGVPIA 943

Query: 562  IVLMVGISCLVP-VKTETLVVPAGLNPTTV--RSWFVPLNPGLETIXXXXXXXXXXXXXX 618
            I++MV +   +    T+ L VP+G + T    R W +                       
Sbjct: 944  ILIMVLVDYSIEDTYTQKLSVPSGFSVTAPEKRGWVINPLGEKSPFPVWMMVASLLPAIL 1003

Query: 619  VYIIVFMETHIAELIIAKPERRLKKGSGFHMDIVIMSFVNALCGMFGAPWQCVATVRSVS 678
            V+I++FMET I  LII+K ER L+KGSGFH+D++++  +  +C +FG PW   ATVRSV+
Sbjct: 1004 VFILIFMETQITTLIISKKERMLQKGSGFHLDLLLIVAMGGICALFGLPWLAAATVRSVT 1063

Query: 679  HVSALTIMSTTHAPGDKPHIVEVKEQRLTGLLVAVMVGISVLASGWLCLVPMAVLFGVFL 738
            H +ALT+MS   APGDKP I EVKEQR+TGLLVA++VG+S++    L  +P+AVLFG+FL
Sbjct: 1064 HANALTVMSKAVAPGDKPKIQEVKEQRVTGLLVALLVGLSIVIGDLLRQIPLAVLFGIFL 1123

Query: 739  YMGISALGGIQFWDRCILLLKPVKHHPQLPYVRRVPTLKMHMYTLIQVGGVVVLYAVKSS 798
            YMG+++L GIQF++R  LLL P KHHP + YV++V TL+MH++T +Q+  + +L+AV S+
Sbjct: 1124 YMGVTSLNGIQFYERLHLLLMPPKHHPDVTYVKKVRTLRMHLFTALQLLCLALLWAVMST 1183

Query: 799  RFSLALPFFLVLMVPLRM-SLVYIFTPLQLRALDG--AQKDIDKDDEPDFYEEAPIP 852
              SLA PF L+L VPLRM  L  IFT  +++ LD   A+   D+ +  D Y E P+P
Sbjct: 1184 AASLAFPFILILTVPLRMVVLTRIFTDREMKCLDANEAEPVFDEREGVDEYNEMPMP 1240


>BC010069-1|AAH10069.1| 1087|Homo sapiens SLC4A2 protein protein.
          Length = 1087

 Score =  612 bits (1511), Expect = e-174
 Identities = 337/777 (43%), Positives = 482/777 (62%), Gaps = 50/777 (6%)

Query: 88   HNDSILKRIPDDAEATTVLVGAVGFLDQPTIAFVRLAEGIYMPSITEVPVPVRFMFILLG 147
            H   +L++IP++AEAT VLVG V FL +PT+AFVRL E + + ++ EVPVPVRF+F+LLG
Sbjct: 348  HELKLLEKIPENAEATVVLVGCVEFLSRPTMAFVRLREAVELDAVLEVPVPVRFLFLLLG 407

Query: 148  PGGADLDYHEVGRSISTLMSNPAFHSIAYKADDRRELLSAINEFLDDSIVLPPGDWERQA 207
            P  A++DYHE+GRSISTLMS+  FH  AY AD+R +LL+AIN FLD S+VLPP + + + 
Sbjct: 408  PSSANMDYHEIGRSISTLMSDKQFHEAAYLADEREDLLTAINAFLDCSVVLPPSEVQGEE 467

Query: 208  LLPLEELRAKSEMIRRRKINALERKRIVADG----DKPSDEKKALLAAEAGGMPPEEPDD 263
            LL       + +M+++R+    E+ R++  G     K + +K  L   EA G      DD
Sbjct: 468  LLR-SVAHFQRQMLKKRE----EQGRLLPTGAGLEPKSAQDKALLQMVEAAGAAE---DD 519

Query: 264  PLSRTGRLFGGVIRDMKRRYPFYVSDFVDALNGQCVAATIFMYFAAVSSAITFGGLLAEK 323
            PL RTGR FGG+IRD++RRYP Y+SDF DAL+ QC+AA IF+YFAA+S AITFGGLL EK
Sbjct: 520  PLRRTGRPFGGLIRDVRRRYPHYLSDFRDALDPQCLAAVIFIYFAALSPAITFGGLLGEK 579

Query: 324  TYGKIGISETLSSGYVRSAVEGDLQVFTSAGGVLFALVAGQPMMITGATGPLLLLDESLA 383
            T   IG+SE + S              T+  GV+F L+  QP+++ G +GPLL+ +E+  
Sbjct: 580  TQDLIGVSELIMS--------------TALQGVVFCLLGAQPLLVIGFSGPLLVFEEAFF 625

Query: 384  NFCHSYGFDFLAARMYCGLWMIVIALCVASVEGSVAVKKITRFTEDXXXXXXXXXXXXEP 443
            +FC S   ++L  R++ G W++ +AL + ++EGS  V+ ++RFT++            E 
Sbjct: 626  SFCSSNHLEYLVGRVWIGFWLVFLALLMVALEGSFLVRFVSRFTQEIFAFLISLIFIYET 685

Query: 444  ITSTIAVYRANPL-GIDYCQFREV-ALSNSTVQPLLNSTSVGNSSVVAPAPPVSRLPPQP 501
                + +++ +PL G       EV    N T      +   GN S+   +    +   QP
Sbjct: 686  FYKLVKIFQEHPLHGCSASNSSEVDGGENMTWAGARPTLGPGNRSLAGQSGQ-GKPRGQP 744

Query: 502  NTALFCTMLTLATFVLAYYLRIFRNGKFLGRSSATSRVQVTGRDGIQARRALGDFGVPIA 561
            NTAL   +L   TF +A++LR F+N +F             GR     RR +GDFGVPIA
Sbjct: 745  NTALLSLVLMAGTFFIAFFLRKFKNSRFF-----------PGR----IRRVIGDFGVPIA 789

Query: 562  IVLMVGISCLVP-VKTETLVVPAGLNPTTV--RSWFVPLNPGLETIXXXXXXXXXXXXXX 618
            I++MV +   +    T+ L VP+G + T    R W +                       
Sbjct: 790  ILIMVLVDYSIEDTYTQKLSVPSGFSVTAPEKRGWVINPLGEKSPFPVWMMVASLLPAIL 849

Query: 619  VYIIVFMETHIAELIIAKPERRLKKGSGFHMDIVIMSFVNALCGMFGAPWQCVATVRSVS 678
            V+I++FMET I  LII+K ER L+KGSGFH+D++++  +  +C +FG PW   ATVRSV+
Sbjct: 850  VFILIFMETQITTLIISKKERMLQKGSGFHLDLLLIVAMGGICALFGLPWLAAATVRSVT 909

Query: 679  HVSALTIMSTTHAPGDKPHIVEVKEQRLTGLLVAVMVGISVLASGWLCLVPMAVLFGVFL 738
            H +ALT+MS   APGDKP I EVKEQR+TGLLVA++VG+S++    L  +P+AVLFG+FL
Sbjct: 910  HANALTVMSKAVAPGDKPKIQEVKEQRVTGLLVALLVGLSIVIGDLLRQIPLAVLFGIFL 969

Query: 739  YMGISALGGIQFWDRCILLLKPVKHHPQLPYVRRVPTLKMHMYTLIQVGGVVVLYAVKSS 798
            YMG+++L GIQF++R  LLL P KHHP + YV++V TL+MH++T +Q+  + +L+AV S+
Sbjct: 970  YMGVTSLNGIQFYERLHLLLMPPKHHPDVTYVKKVRTLRMHLFTALQLLCLALLWAVMST 1029

Query: 799  RFSLALPFFLVLMVPLRM-SLVYIFTPLQLRALDG--AQKDIDKDDEPDFYEEAPIP 852
              SLA PF L+L VPLRM  L  IFT  +++ LD   A+   D+ +  D Y E P+P
Sbjct: 1030 AASLAFPFILILTVPLRMVVLTRIFTDREMKCLDANEAEPVFDEREGVDEYNEMPMP 1086


>BC009434-1|AAH09434.1| 1227|Homo sapiens SLC4A2 protein protein.
          Length = 1227

 Score =  612 bits (1511), Expect = e-174
 Identities = 337/777 (43%), Positives = 482/777 (62%), Gaps = 50/777 (6%)

Query: 88   HNDSILKRIPDDAEATTVLVGAVGFLDQPTIAFVRLAEGIYMPSITEVPVPVRFMFILLG 147
            H   +L++IP++AEAT VLVG V FL +PT+AFVRL E + + ++ EVPVPVRF+F+LLG
Sbjct: 488  HELKLLEKIPENAEATVVLVGCVEFLSRPTMAFVRLREAVELDAVLEVPVPVRFLFLLLG 547

Query: 148  PGGADLDYHEVGRSISTLMSNPAFHSIAYKADDRRELLSAINEFLDDSIVLPPGDWERQA 207
            P  A++DYHE+GRSISTLMS+  FH  AY AD+R +LL+AIN FLD S+VLPP + + + 
Sbjct: 548  PSSANMDYHEIGRSISTLMSDKQFHEAAYLADEREDLLTAINAFLDCSVVLPPSEVQGEE 607

Query: 208  LLPLEELRAKSEMIRRRKINALERKRIVADG----DKPSDEKKALLAAEAGGMPPEEPDD 263
            LL       + +M+++R+    E+ R++  G     K + +K  L   EA G      DD
Sbjct: 608  LLR-SVAHFQRQMLKKRE----EQGRLLPTGAGLEPKSAQDKALLQMVEAAGAAE---DD 659

Query: 264  PLSRTGRLFGGVIRDMKRRYPFYVSDFVDALNGQCVAATIFMYFAAVSSAITFGGLLAEK 323
            PL RTGR FGG+IRD++RRYP Y+SDF DAL+ QC+AA IF+YFAA+S AITFGGLL EK
Sbjct: 660  PLRRTGRPFGGLIRDVRRRYPHYLSDFRDALDPQCLAAVIFIYFAALSPAITFGGLLGEK 719

Query: 324  TYGKIGISETLSSGYVRSAVEGDLQVFTSAGGVLFALVAGQPMMITGATGPLLLLDESLA 383
            T   IG+SE + S              T+  GV+F L+  QP+++ G +GPLL+ +E+  
Sbjct: 720  TQDLIGVSELIMS--------------TALQGVVFCLLGAQPLLVIGFSGPLLVFEEAFF 765

Query: 384  NFCHSYGFDFLAARMYCGLWMIVIALCVASVEGSVAVKKITRFTEDXXXXXXXXXXXXEP 443
            +FC S   ++L  R++ G W++ +AL + ++EGS  V+ ++RFT++            E 
Sbjct: 766  SFCSSNHLEYLVGRVWIGFWLVFLALLMVALEGSFLVRFVSRFTQEIFAFLISLIFIYET 825

Query: 444  ITSTIAVYRANPL-GIDYCQFREV-ALSNSTVQPLLNSTSVGNSSVVAPAPPVSRLPPQP 501
                + +++ +PL G       EV    N T      +   GN S+   +    +   QP
Sbjct: 826  FYKLVKIFQEHPLHGCSASNSSEVDGGENMTWAGARPTLGPGNRSLAGQSGQ-GKPRGQP 884

Query: 502  NTALFCTMLTLATFVLAYYLRIFRNGKFLGRSSATSRVQVTGRDGIQARRALGDFGVPIA 561
            NTAL   +L   TF +A++LR F+N +F             GR     RR +GDFGVPIA
Sbjct: 885  NTALLSLVLMAGTFFIAFFLRKFKNSRFF-----------PGR----IRRVIGDFGVPIA 929

Query: 562  IVLMVGISCLVP-VKTETLVVPAGLNPTTV--RSWFVPLNPGLETIXXXXXXXXXXXXXX 618
            I++MV +   +    T+ L VP+G + T    R W +                       
Sbjct: 930  ILIMVLVDYSIEDTYTQKLSVPSGFSVTAPEKRGWVINPLGEKSPFPVWMMVASLLPAIL 989

Query: 619  VYIIVFMETHIAELIIAKPERRLKKGSGFHMDIVIMSFVNALCGMFGAPWQCVATVRSVS 678
            V+I++FMET I  LII+K ER L+KGSGFH+D++++  +  +C +FG PW   ATVRSV+
Sbjct: 990  VFILIFMETQITTLIISKKERMLQKGSGFHLDLLLIVAMGGICALFGLPWLAAATVRSVT 1049

Query: 679  HVSALTIMSTTHAPGDKPHIVEVKEQRLTGLLVAVMVGISVLASGWLCLVPMAVLFGVFL 738
            H +ALT+MS   APGDKP I EVKEQR+TGLLVA++VG+S++    L  +P+AVLFG+FL
Sbjct: 1050 HANALTVMSKAVAPGDKPKIQEVKEQRVTGLLVALLVGLSIVIGDLLRQIPLAVLFGIFL 1109

Query: 739  YMGISALGGIQFWDRCILLLKPVKHHPQLPYVRRVPTLKMHMYTLIQVGGVVVLYAVKSS 798
            YMG+++L GIQF++R  LLL P KHHP + YV++V TL+MH++T +Q+  + +L+AV S+
Sbjct: 1110 YMGVTSLNGIQFYERLHLLLMPPKHHPDVTYVKKVRTLRMHLFTALQLLCLALLWAVMST 1169

Query: 799  RFSLALPFFLVLMVPLRM-SLVYIFTPLQLRALDG--AQKDIDKDDEPDFYEEAPIP 852
              SLA PF L+L VPLRM  L  IFT  +++ LD   A+   D+ +  D Y E P+P
Sbjct: 1170 AASLAFPFILILTVPLRMVVLTRIFTDREMKCLDANEAEPVFDEREGVDEYNEMPMP 1226


>BC009386-1|AAH09386.1| 1227|Homo sapiens SLC4A2 protein protein.
          Length = 1227

 Score =  612 bits (1511), Expect = e-174
 Identities = 337/777 (43%), Positives = 482/777 (62%), Gaps = 50/777 (6%)

Query: 88   HNDSILKRIPDDAEATTVLVGAVGFLDQPTIAFVRLAEGIYMPSITEVPVPVRFMFILLG 147
            H   +L++IP++AEAT VLVG V FL +PT+AFVRL E + + ++ EVPVPVRF+F+LLG
Sbjct: 488  HELKLLEKIPENAEATVVLVGCVEFLSRPTMAFVRLREAVELDAVLEVPVPVRFLFLLLG 547

Query: 148  PGGADLDYHEVGRSISTLMSNPAFHSIAYKADDRRELLSAINEFLDDSIVLPPGDWERQA 207
            P  A++DYHE+GRSISTLMS+  FH  AY AD+R +LL+AIN FLD S+VLPP + + + 
Sbjct: 548  PSSANMDYHEIGRSISTLMSDKQFHEAAYLADEREDLLTAINAFLDCSVVLPPSEVQGEE 607

Query: 208  LLPLEELRAKSEMIRRRKINALERKRIVADG----DKPSDEKKALLAAEAGGMPPEEPDD 263
            LL       + +M+++R+    E+ R++  G     K + +K  L   EA G      DD
Sbjct: 608  LLR-SVAHFQRQMLKKRE----EQGRLLPTGAGLEPKSAQDKALLQMVEAAGAAE---DD 659

Query: 264  PLSRTGRLFGGVIRDMKRRYPFYVSDFVDALNGQCVAATIFMYFAAVSSAITFGGLLAEK 323
            PL RTGR FGG+IRD++RRYP Y+SDF DAL+ QC+AA IF+YFAA+S AITFGGLL EK
Sbjct: 660  PLRRTGRPFGGLIRDVRRRYPHYLSDFRDALDPQCLAAVIFIYFAALSPAITFGGLLGEK 719

Query: 324  TYGKIGISETLSSGYVRSAVEGDLQVFTSAGGVLFALVAGQPMMITGATGPLLLLDESLA 383
            T   IG+SE + S              T+  GV+F L+  QP+++ G +GPLL+ +E+  
Sbjct: 720  TQDLIGVSELIMS--------------TALQGVVFCLLGAQPLLVIGFSGPLLVFEEAFF 765

Query: 384  NFCHSYGFDFLAARMYCGLWMIVIALCVASVEGSVAVKKITRFTEDXXXXXXXXXXXXEP 443
            +FC S   ++L  R++ G W++ +AL + ++EGS  V+ ++RFT++            E 
Sbjct: 766  SFCSSNHLEYLVGRVWIGFWLVFLALLMVALEGSFLVRFVSRFTQEIFAFLISLIFIYET 825

Query: 444  ITSTIAVYRANPL-GIDYCQFREV-ALSNSTVQPLLNSTSVGNSSVVAPAPPVSRLPPQP 501
                + +++ +PL G       EV    N T      +   GN S+   +    +   QP
Sbjct: 826  FYKLVKIFQEHPLHGCSASNSSEVDGGENMTWAGARPTLGPGNRSLAGQSGQ-GKPRGQP 884

Query: 502  NTALFCTMLTLATFVLAYYLRIFRNGKFLGRSSATSRVQVTGRDGIQARRALGDFGVPIA 561
            NTAL   +L   TF +A++LR F+N +F             GR     RR +GDFGVPIA
Sbjct: 885  NTALLSLVLMAGTFFIAFFLRKFKNSRFF-----------PGR----IRRVIGDFGVPIA 929

Query: 562  IVLMVGISCLVP-VKTETLVVPAGLNPTTV--RSWFVPLNPGLETIXXXXXXXXXXXXXX 618
            I++MV +   +    T+ L VP+G + T    R W +                       
Sbjct: 930  ILIMVLVDYSIEDTYTQKLSVPSGFSVTAPEKRGWVINPLGEKSPFPVWMMVASLLPAIL 989

Query: 619  VYIIVFMETHIAELIIAKPERRLKKGSGFHMDIVIMSFVNALCGMFGAPWQCVATVRSVS 678
            V+I++FMET I  LII+K ER L+KGSGFH+D++++  +  +C +FG PW   ATVRSV+
Sbjct: 990  VFILIFMETQITTLIISKKERMLQKGSGFHLDLLLIVAMGGICALFGLPWLAAATVRSVT 1049

Query: 679  HVSALTIMSTTHAPGDKPHIVEVKEQRLTGLLVAVMVGISVLASGWLCLVPMAVLFGVFL 738
            H +ALT+MS   APGDKP I EVKEQR+TGLLVA++VG+S++    L  +P+AVLFG+FL
Sbjct: 1050 HANALTVMSKAVAPGDKPKIQEVKEQRVTGLLVALLVGLSIVIGDLLRQIPLAVLFGIFL 1109

Query: 739  YMGISALGGIQFWDRCILLLKPVKHHPQLPYVRRVPTLKMHMYTLIQVGGVVVLYAVKSS 798
            YMG+++L GIQF++R  LLL P KHHP + YV++V TL+MH++T +Q+  + +L+AV S+
Sbjct: 1110 YMGVTSLNGIQFYERLHLLLMPPKHHPDVTYVKKVRTLRMHLFTALQLLCLALLWAVMST 1169

Query: 799  RFSLALPFFLVLMVPLRM-SLVYIFTPLQLRALDG--AQKDIDKDDEPDFYEEAPIP 852
              SLA PF L+L VPLRM  L  IFT  +++ LD   A+   D+ +  D Y E P+P
Sbjct: 1170 AASLAFPFILILTVPLRMVVLTRIFTDREMKCLDANEAEPVFDEREGVDEYNEMPMP 1226


>BC004893-1|AAH04893.1| 1087|Homo sapiens SLC4A2 protein protein.
          Length = 1087

 Score =  612 bits (1511), Expect = e-174
 Identities = 337/777 (43%), Positives = 482/777 (62%), Gaps = 50/777 (6%)

Query: 88   HNDSILKRIPDDAEATTVLVGAVGFLDQPTIAFVRLAEGIYMPSITEVPVPVRFMFILLG 147
            H   +L++IP++AEAT VLVG V FL +PT+AFVRL E + + ++ EVPVPVRF+F+LLG
Sbjct: 348  HELKLLEKIPENAEATVVLVGCVEFLSRPTMAFVRLREAVELDAVLEVPVPVRFLFLLLG 407

Query: 148  PGGADLDYHEVGRSISTLMSNPAFHSIAYKADDRRELLSAINEFLDDSIVLPPGDWERQA 207
            P  A++DYHE+GRSISTLMS+  FH  AY AD+R +LL+AIN FLD S+VLPP + + + 
Sbjct: 408  PSSANMDYHEIGRSISTLMSDKQFHEAAYLADEREDLLTAINAFLDCSVVLPPSEVQGEE 467

Query: 208  LLPLEELRAKSEMIRRRKINALERKRIVADG----DKPSDEKKALLAAEAGGMPPEEPDD 263
            LL       + +M+++R+    E+ R++  G     K + +K  L   EA G      DD
Sbjct: 468  LLR-SVAHFQRQMLKKRE----EQGRLLPTGAGLEPKSAQDKALLQMVEAAGAAE---DD 519

Query: 264  PLSRTGRLFGGVIRDMKRRYPFYVSDFVDALNGQCVAATIFMYFAAVSSAITFGGLLAEK 323
            PL RTGR FGG+IRD++RRYP Y+SDF DAL+ QC+AA IF+YFAA+S AITFGGLL EK
Sbjct: 520  PLRRTGRPFGGLIRDVRRRYPHYLSDFRDALDPQCLAAVIFIYFAALSPAITFGGLLGEK 579

Query: 324  TYGKIGISETLSSGYVRSAVEGDLQVFTSAGGVLFALVAGQPMMITGATGPLLLLDESLA 383
            T   IG+SE + S              T+  GV+F L+  QP+++ G +GPLL+ +E+  
Sbjct: 580  TQDLIGVSELIMS--------------TALQGVVFCLLGAQPLLVIGFSGPLLVFEEAFF 625

Query: 384  NFCHSYGFDFLAARMYCGLWMIVIALCVASVEGSVAVKKITRFTEDXXXXXXXXXXXXEP 443
            +FC S   ++L  R++ G W++ +AL + ++EGS  V+ ++RFT++            E 
Sbjct: 626  SFCSSNHLEYLVGRVWIGFWLVFLALLMVALEGSFLVRFVSRFTQEIFAFLISLIFIYET 685

Query: 444  ITSTIAVYRANPL-GIDYCQFREV-ALSNSTVQPLLNSTSVGNSSVVAPAPPVSRLPPQP 501
                + +++ +PL G       EV    N T      +   GN S+   +    +   QP
Sbjct: 686  FYKLVKIFQEHPLHGCSASNSSEVDGGENMTWAGARPTLGPGNRSLAGQSGQ-GKPRGQP 744

Query: 502  NTALFCTMLTLATFVLAYYLRIFRNGKFLGRSSATSRVQVTGRDGIQARRALGDFGVPIA 561
            NTAL   +L   TF +A++LR F+N +F             GR     RR +GDFGVPIA
Sbjct: 745  NTALLSLVLMAGTFFIAFFLRKFKNSRFF-----------PGR----IRRVIGDFGVPIA 789

Query: 562  IVLMVGISCLVP-VKTETLVVPAGLNPTTV--RSWFVPLNPGLETIXXXXXXXXXXXXXX 618
            I++MV +   +    T+ L VP+G + T    R W +                       
Sbjct: 790  ILIMVLVDYSIEDTYTQKLSVPSGFSVTAPEKRGWVINPLGEKSPFPVWMMVASLLPAIL 849

Query: 619  VYIIVFMETHIAELIIAKPERRLKKGSGFHMDIVIMSFVNALCGMFGAPWQCVATVRSVS 678
            V+I++FMET I  LII+K ER L+KGSGFH+D++++  +  +C +FG PW   ATVRSV+
Sbjct: 850  VFILIFMETQITTLIISKKERMLQKGSGFHLDLLLIVAMGGICALFGLPWLAAATVRSVT 909

Query: 679  HVSALTIMSTTHAPGDKPHIVEVKEQRLTGLLVAVMVGISVLASGWLCLVPMAVLFGVFL 738
            H +ALT+MS   APGDKP I EVKEQR+TGLLVA++VG+S++    L  +P+AVLFG+FL
Sbjct: 910  HANALTVMSKAVAPGDKPKIQEVKEQRVTGLLVALLVGLSIVIGDLLRQIPLAVLFGIFL 969

Query: 739  YMGISALGGIQFWDRCILLLKPVKHHPQLPYVRRVPTLKMHMYTLIQVGGVVVLYAVKSS 798
            YMG+++L GIQF++R  LLL P KHHP + YV++V TL+MH++T +Q+  + +L+AV S+
Sbjct: 970  YMGVTSLNGIQFYERLHLLLMPPKHHPDVTYVKKVRTLRMHLFTALQLLCLALLWAVMST 1029

Query: 799  RFSLALPFFLVLMVPLRM-SLVYIFTPLQLRALDG--AQKDIDKDDEPDFYEEAPIP 852
              SLA PF L+L VPLRM  L  IFT  +++ LD   A+   D+ +  D Y E P+P
Sbjct: 1030 AASLAFPFILILTVPLRMVVLTRIFTDREMKCLDANEAEPVFDEREGVDEYNEMPMP 1086


>AB209158-1|BAD92395.1| 1244|Homo sapiens Anion exchanger 2 type a
            variant protein.
          Length = 1244

 Score =  612 bits (1511), Expect = e-174
 Identities = 337/777 (43%), Positives = 482/777 (62%), Gaps = 50/777 (6%)

Query: 88   HNDSILKRIPDDAEATTVLVGAVGFLDQPTIAFVRLAEGIYMPSITEVPVPVRFMFILLG 147
            H   +L++IP++AEAT VLVG V FL +PT+AFVRL E + + ++ EVPVPVRF+F+LLG
Sbjct: 505  HELKLLEKIPENAEATVVLVGCVEFLSRPTMAFVRLREAVELDAVLEVPVPVRFLFLLLG 564

Query: 148  PGGADLDYHEVGRSISTLMSNPAFHSIAYKADDRRELLSAINEFLDDSIVLPPGDWERQA 207
            P  A++DYHE+GRSISTLMS+  FH  AY AD+R +LL+AIN FLD S+VLPP + + + 
Sbjct: 565  PSSANMDYHEIGRSISTLMSDKQFHEAAYLADEREDLLTAINAFLDCSVVLPPSEVQGEE 624

Query: 208  LLPLEELRAKSEMIRRRKINALERKRIVADG----DKPSDEKKALLAAEAGGMPPEEPDD 263
            LL       + +M+++R+    E+ R++  G     K + +K  L   EA G      DD
Sbjct: 625  LLR-SVAHFQRQMLKKRE----EQGRLLPTGAGLEPKSAQDKALLQMVEAAGAAE---DD 676

Query: 264  PLSRTGRLFGGVIRDMKRRYPFYVSDFVDALNGQCVAATIFMYFAAVSSAITFGGLLAEK 323
            PL RTGR FGG+IRD++RRYP Y+SDF DAL+ QC+AA IF+YFAA+S AITFGGLL EK
Sbjct: 677  PLRRTGRPFGGLIRDVRRRYPHYLSDFRDALDPQCLAAVIFIYFAALSPAITFGGLLGEK 736

Query: 324  TYGKIGISETLSSGYVRSAVEGDLQVFTSAGGVLFALVAGQPMMITGATGPLLLLDESLA 383
            T   IG+SE + S              T+  GV+F L+  QP+++ G +GPLL+ +E+  
Sbjct: 737  TQDLIGVSELIMS--------------TALQGVVFCLLGAQPLLVIGFSGPLLVFEEAFF 782

Query: 384  NFCHSYGFDFLAARMYCGLWMIVIALCVASVEGSVAVKKITRFTEDXXXXXXXXXXXXEP 443
            +FC S   ++L  R++ G W++ +AL + ++EGS  V+ ++RFT++            E 
Sbjct: 783  SFCSSNHLEYLVGRVWIGFWLVFLALLMVALEGSFLVRFVSRFTQEIFAFLISLIFIYET 842

Query: 444  ITSTIAVYRANPL-GIDYCQFREV-ALSNSTVQPLLNSTSVGNSSVVAPAPPVSRLPPQP 501
                + +++ +PL G       EV    N T      +   GN S+   +    +   QP
Sbjct: 843  FYKLVKIFQEHPLHGCSASNSSEVDGGENMTWAGARPTLGPGNRSLAGQSGQ-GKPRGQP 901

Query: 502  NTALFCTMLTLATFVLAYYLRIFRNGKFLGRSSATSRVQVTGRDGIQARRALGDFGVPIA 561
            NTAL   +L   TF +A++LR F+N +F             GR     RR +GDFGVPIA
Sbjct: 902  NTALLSLVLMAGTFFIAFFLRKFKNSRFF-----------PGR----IRRVIGDFGVPIA 946

Query: 562  IVLMVGISCLVP-VKTETLVVPAGLNPTTV--RSWFVPLNPGLETIXXXXXXXXXXXXXX 618
            I++MV +   +    T+ L VP+G + T    R W +                       
Sbjct: 947  ILIMVLVDYSIEDTYTQKLSVPSGFSVTAPEKRGWVINPLGEKSPFPVWMMVASLLPAIL 1006

Query: 619  VYIIVFMETHIAELIIAKPERRLKKGSGFHMDIVIMSFVNALCGMFGAPWQCVATVRSVS 678
            V+I++FMET I  LII+K ER L+KGSGFH+D++++  +  +C +FG PW   ATVRSV+
Sbjct: 1007 VFILIFMETQITTLIISKKERMLQKGSGFHLDLLLIVAMGGICALFGLPWLAAATVRSVT 1066

Query: 679  HVSALTIMSTTHAPGDKPHIVEVKEQRLTGLLVAVMVGISVLASGWLCLVPMAVLFGVFL 738
            H +ALT+MS   APGDKP I EVKEQR+TGLLVA++VG+S++    L  +P+AVLFG+FL
Sbjct: 1067 HANALTVMSKAVAPGDKPKIQEVKEQRVTGLLVALLVGLSIVIGDLLRQIPLAVLFGIFL 1126

Query: 739  YMGISALGGIQFWDRCILLLKPVKHHPQLPYVRRVPTLKMHMYTLIQVGGVVVLYAVKSS 798
            YMG+++L GIQF++R  LLL P KHHP + YV++V TL+MH++T +Q+  + +L+AV S+
Sbjct: 1127 YMGVTSLNGIQFYERLHLLLMPPKHHPDVTYVKKVRTLRMHLFTALQLLCLALLWAVMST 1186

Query: 799  RFSLALPFFLVLMVPLRM-SLVYIFTPLQLRALDG--AQKDIDKDDEPDFYEEAPIP 852
              SLA PF L+L VPLRM  L  IFT  +++ LD   A+   D+ +  D Y E P+P
Sbjct: 1187 AASLAFPFILILTVPLRMVVLTRIFTDREMKCLDANEAEPVFDEREGVDEYNEMPMP 1243


>BC028601-1|AAH28601.1| 1159|Homo sapiens SLC4A2 protein protein.
          Length = 1159

 Score =  610 bits (1506), Expect = e-174
 Identities = 336/777 (43%), Positives = 481/777 (61%), Gaps = 50/777 (6%)

Query: 88   HNDSILKRIPDDAEATTVLVGAVGFLDQPTIAFVRLAEGIYMPSITEVPVPVRFMFILLG 147
            H   +L++IP++AEAT VLVG V FL +PT+AFVRL E + + ++ EVPVPVRF+F+LLG
Sbjct: 420  HELKLLEKIPENAEATVVLVGCVEFLSRPTMAFVRLREAVELDAVLEVPVPVRFLFLLLG 479

Query: 148  PGGADLDYHEVGRSISTLMSNPAFHSIAYKADDRRELLSAINEFLDDSIVLPPGDWERQA 207
            P  A++DYHE+GRSISTLMS+  FH  AY AD+R +LL+AIN FLD S+VLPP + + + 
Sbjct: 480  PSSANMDYHEIGRSISTLMSDKQFHEAAYLADEREDLLTAINAFLDCSVVLPPSEVQGEE 539

Query: 208  LLPLEELRAKSEMIRRRKINALERKRIVADG----DKPSDEKKALLAAEAGGMPPEEPDD 263
            LL       + +M+++R+    E+ R++  G     K + +K  L   EA G      DD
Sbjct: 540  LLR-SVAHFQRQMLKKRE----EQGRLLPTGAGLEPKSAQDKALLQMVEAAGAAE---DD 591

Query: 264  PLSRTGRLFGGVIRDMKRRYPFYVSDFVDALNGQCVAATIFMYFAAVSSAITFGGLLAEK 323
            PL RTGR FGG+IRD++RRYP Y+SDF DAL+ QC+AA IF+YFAA+S AITFGGLL EK
Sbjct: 592  PLRRTGRPFGGLIRDVRRRYPHYLSDFRDALDPQCLAAVIFIYFAALSPAITFGGLLGEK 651

Query: 324  TYGKIGISETLSSGYVRSAVEGDLQVFTSAGGVLFALVAGQPMMITGATGPLLLLDESLA 383
            T   IG+SE + S              T+  GV+F L+  QP+++ G +GPLL+ +E+  
Sbjct: 652  TQDLIGVSELIMS--------------TALQGVVFCLLGAQPLLVIGFSGPLLVFEEAFF 697

Query: 384  NFCHSYGFDFLAARMYCGLWMIVIALCVASVEGSVAVKKITRFTEDXXXXXXXXXXXXEP 443
            +FC S   ++L  R++ G W++ +AL + ++EGS  V+ ++RFT++            E 
Sbjct: 698  SFCSSNHLEYLVGRVWIGFWLVFLALLMVALEGSFLVRFVSRFTQEIFAFLISLIFIYET 757

Query: 444  ITSTIAVYRANPL-GIDYCQFREV-ALSNSTVQPLLNSTSVGNSSVVAPAPPVSRLPPQP 501
                + +++ +PL G       EV    N T      +   GN S+   +    +   QP
Sbjct: 758  FYKLVKIFQEHPLHGCSASNSSEVDGGENMTWAGARPTLGPGNRSLAGQSGQ-GKPRGQP 816

Query: 502  NTALFCTMLTLATFVLAYYLRIFRNGKFLGRSSATSRVQVTGRDGIQARRALGDFGVPIA 561
            NTAL   +L   TF +A++LR F+N +F             GR     RR +GDFGVPIA
Sbjct: 817  NTALLSLVLMAGTFFIAFFLRKFKNSRFF-----------PGR----IRRVIGDFGVPIA 861

Query: 562  IVLMVGISCLVP-VKTETLVVPAGLNPTTV--RSWFVPLNPGLETIXXXXXXXXXXXXXX 618
            I++MV +   +    T+ L VP+G + T    R W +                       
Sbjct: 862  ILIMVLVDYSIEDTYTQKLSVPSGFSVTAPEKRGWVINPLGEKSPFPVWMMVASLLPAIL 921

Query: 619  VYIIVFMETHIAELIIAKPERRLKKGSGFHMDIVIMSFVNALCGMFGAPWQCVATVRSVS 678
            V+I++FMET I  LII+K ER L+KGSGFH+D++++  +  +C +FG PW   ATVRSV+
Sbjct: 922  VFILIFMETQITTLIISKKERMLQKGSGFHLDLLLIVAMGGICALFGLPWLAAATVRSVT 981

Query: 679  HVSALTIMSTTHAPGDKPHIVEVKEQRLTGLLVAVMVGISVLASGWLCLVPMAVLFGVFL 738
            H +ALT+MS   APGDKP I EVKEQR+TGLLVA++VG+S++    L  +P+AVLFG+FL
Sbjct: 982  HANALTVMSKAVAPGDKPKIQEVKEQRVTGLLVALLVGLSIVIGDLLRQIPLAVLFGIFL 1041

Query: 739  YMGISALGGIQFWDRCILLLKPVKHHPQLPYVRRVPTLKMHMYTLIQVGGVVVLYAVKSS 798
            YMG+++L G QF++R  LLL P KHHP + YV++V TL+MH++T +Q+  + +L+AV S+
Sbjct: 1042 YMGVTSLNGTQFYERLHLLLMPPKHHPDVTYVKKVRTLRMHLFTALQLLCLALLWAVMST 1101

Query: 799  RFSLALPFFLVLMVPLRM-SLVYIFTPLQLRALDG--AQKDIDKDDEPDFYEEAPIP 852
              SLA PF L+L VPLRM  L  IFT  +++ LD   A+   D+ +  D Y E P+P
Sbjct: 1102 AASLAFPFILILTVPLRMVVLTRIFTDREMKCLDANEAEPVFDEREGVDEYNEMPMP 1158


>L27213-1|AAB05850.1|  932|Homo sapiens anion exchange protein
           protein.
          Length = 932

 Score =  601 bits (1485), Expect = e-171
 Identities = 330/767 (43%), Positives = 471/767 (61%), Gaps = 50/767 (6%)

Query: 92  ILKRIPDDAEATTVLVGAVGFLDQPTIAFVRLAEGIYMPSITEVPVPVRFMFILLGPGGA 151
           +L++IP+DAEAT VLVG V FL+QP  AFVRL E + + S+ EVPVPVRF+F++LGP   
Sbjct: 209 LLEKIPEDAEATVVLVGCVPFLEQPAAAFVRLNEAVLLESVLEVPVPVRFLFVMLGPSHT 268

Query: 152 DLDYHEVGRSISTLMSNPAFHSIAYKADDRRELLSAINEFLDDSIVLPPGDWERQALLPL 211
             DYHE+GRSI+TLMS+  FH  AY+ADDR++LLSAI+EFLD  IV+PP + E + LL  
Sbjct: 269 STDYHELGRSIATLMSDKLFHEAAYQADDRQDLLSAISEFLDGGIVIPPSEVEGRDLL-R 327

Query: 212 EELRAKSEMIRRRKINALERKRIVADGDKPSDEKKALLAAEAGGMPPEEPDDPLSRTGRL 271
                + E++R+R+     +  +   G   +  K+  L+ E GG      DDPL RTG +
Sbjct: 328 SVAAFQRELLRKRREREQTKVEMTTRGGYTAPGKE--LSLELGGSEATPEDDPLLRTGSV 385

Query: 272 FGGVIRDMKRRYPFYVSDFVDALNGQCVAATIFMYFAAVSSAITFGGLLAEKTYGKIGIS 331
           FGG++RD++RRYP Y SD   AL+ QCVAA +F+YFAA+S AITFGGLL EKT G +G+S
Sbjct: 386 FGGLVRDVRRRYPHYPSDLRAALHSQCVAAVLFIYFAALSPAITFGGLLGEKTEGLMGVS 445

Query: 332 ETLSSGYVRSAVEGDLQVFTSAGGVLFALVAGQPMMITGATGPLLLLDESLANFCHSYGF 391
           E              L V T+  GVLF+L+  QP+++ G +GPLL+ +E+   FC +   
Sbjct: 446 E--------------LIVSTAVLGVLFSLLGAQPLLVVGFSGPLLVFEEAFFKFCRAQDL 491

Query: 392 DFLAARMYCGLWMIVIALCVASVEGSVAVKKITRFTEDXXXXXXXXXXXXEPITSTIAVY 451
           ++L  R++ GLW++V  L + + E    V+ I+  T++            E       V+
Sbjct: 492 EYLTGRVWVGLWLVVFVLALVAAEFIFLVRYISPLTQEIFAFLISLIFIYETFYKLYKVF 551

Query: 452 RANPLGIDYCQFREVALSNSTVQPLLNSTSVGNSSVVAPAPPVSRLPPQPNTALFCTMLT 511
             +PL   Y    E +L ++ ++P        N   + P         QPNTAL   +  
Sbjct: 552 TEHPLLPFYPP--EGSL-DAGLEP--------NGCALPPTEGPPGPENQPNTALLSLIPM 600

Query: 512 LATFVLAYYLRIFRNGKFLGRSSATSRVQVTGRDGIQARRALGDFGVPIAIVLMVGIS-C 570
           L TF +A++LR FRN +FLG                +ARR +GDFG+PI+I++MV +   
Sbjct: 601 LGTFFIAFFLRKFRNSRFLGG---------------KARRIIGDFGIPISILVMVLVDYS 645

Query: 571 LVPVKTETLVVPAGLNPTT--VRSWFVPLNPGLETIXXXXXXXXXXXXXXVYIIVFMETH 628
           +    T+ L VP GL+ T+   RSWF+P                      V I++FMET 
Sbjct: 646 ITDTYTQKLTVPTGLSVTSPDKRSWFIPPLGSARPFPPWMMVAAAVPALLVLILIFMETQ 705

Query: 629 IAELIIAKPERRLKKGSGFHMDIVIMSFVNALCGMFGAPWQCVATVRSVSHVSALTIMST 688
           I  LI+++  RRL KGSGFH+D++++  +  LCG+FG PW   ATVRSV+HV+ALT+M T
Sbjct: 706 ITALIVSQKARRLLKGSGFHLDLLLIGSLGGLCGLFGLPWLTAATVRSVTHVNALTVMRT 765

Query: 689 THAPGDKPHIVEVKEQRLTGLLVAVMVGISVLASGWLCLVPMAVLFGVFLYMGISALGGI 748
             APGDKP I EV+EQR+TG+L+A +VG+S++    L  +P+AVLFG+FLYMG+++L GI
Sbjct: 766 AIAPGDKPQIQEVREQRVTGVLIASLVGLSMVMGAVLRRIPLAVLFGIFLYMGVTSLSGI 825

Query: 749 QFWDRCILLLKPVKHHPQLPYVRRVPTLKMHMYTLIQVGGVVVLYAVKSSRFSLALPFFL 808
           Q   R +L+L P KHHP+ PYV +V T +MH++T IQ+G + +L+ VKS+  SLA PF L
Sbjct: 826 QLSQRLLLILMPAKHHPEQPYVTKVKTWRMHLFTCIQLGCIALLWVVKSTAASLAFPFLL 885

Query: 809 VLMVPLRMSLV-YIFTPLQLRALDG--AQKDIDKDDEPDFYEEAPIP 852
           +L VPLR  L+  +F   +L+ALD   A+ + D+D + D Y E  +P
Sbjct: 886 LLTVPLRHCLLPRLFQDRELQALDSEDAEPNFDEDGQ-DEYNELHMP 931


>X62137-1|CAA44067.1| 1240|Homo sapiens anion exchange protein 2 (AE2)
            protein.
          Length = 1240

 Score =  591 bits (1460), Expect = e-168
 Identities = 330/777 (42%), Positives = 474/777 (61%), Gaps = 51/777 (6%)

Query: 88   HNDSILKRIPDDAEATTVLVGAVGFLDQPTIAFVRLAEGIYMPSITEVPVPVRFMFILLG 147
            H   +L++IP++AEAT VLVG V FL +PT+AFVRL E + + ++ EVPVPVRF+F+LLG
Sbjct: 502  HELKLLEKIPENAEATVVLVGCVEFLSRPTMAFVRLREAVELDAVLEVPVPVRFLFLLLG 561

Query: 148  PGGADLDYHEVGRSISTLMSNPAFHSIAYKADDRRELLSAINEFLDDSIVLPPGDWERQA 207
            P  A++DYHE+GRSISTLMS+  FH  AY AD+R +LL+AIN FLD S+VLPP + + + 
Sbjct: 562  PSSANMDYHEIGRSISTLMSDKQFHEAAYLADEREDLLTAINAFLDCSVVLPPSEVQGEE 621

Query: 208  LLPLEELRAKSEMIRRRKINALERKRIVADG----DKPSDEKKALLAAEAGGMPPEEPDD 263
            LL       + +M+++R+    E+ R++  G     K + +K  L   E  G     P  
Sbjct: 622  LLR-SVAHFQRQMLKKRE----EQGRLLPTGAGLEPKSAQDKALLQMVERQGQLKMIP-- 674

Query: 264  PLSRTGRLFGGVIRDMKRRYPFYVSDFVDALNGQCVAATIFMYFAAVSSAITFGGLLAEK 323
              S  G  FGG+IRD++RRYP Y+SDF DAL+ QC+AA IF+YFAA+S AITFGGLL EK
Sbjct: 675  --SADGAAFGGLIRDVRRRYPHYLSDFRDALDPQCLAAVIFIYFAALSPAITFGGLLGEK 732

Query: 324  TYGKIGISETLSSGYVRSAVEGDLQVFTSAGGVLFALVAGQPMMITGATGPLLLLDESLA 383
            T   IG+SE + S              T+  GV+F L+  QP+++ G +GPLL+ +E+  
Sbjct: 733  TQDLIGVSELIMS--------------TALQGVVFCLLGAQPLLVIGFSGPLLVFEEAFF 778

Query: 384  NFCHSYGFDFLAARMYCGLWMIVIALCVASVEGSVAVKKITRFTEDXXXXXXXXXXXXEP 443
            +FC S   ++L  R++ G W++ +AL + ++EGS  V+ ++RFT +            E 
Sbjct: 779  SFCSSNHLEYLVGRVWIGFWLVFLALLMVALEGSFLVRFVSRFTREIFAFLISLIFIYET 838

Query: 444  ITSTIAVYRANPL-GIDYCQFREV-ALSNSTVQPLLNSTSVGNSSVVAPAPPVSRLPPQP 501
                + +++ +PL G       EV    N T      +   GN S+   +    +   QP
Sbjct: 839  FYKLVKIFQEHPLHGCSASNSSEVDGGENMTWAGARPTLGPGNRSLAGQSGQ-GKPRGQP 897

Query: 502  NTALFCTMLTLATFVLAYYLRIFRNGKFLGRSSATSRVQVTGRDGIQARRALGDFGVPIA 561
            NTA    +L   TF +A++LR F+N +F             GR     RR +GDFGVPIA
Sbjct: 898  NTAPLSLVLMAGTFFIAFFLRKFKNSRFF-----------PGR----IRRVIGDFGVPIA 942

Query: 562  IVLMVGISCLVP-VKTETLVVPAGLNPTTV--RSWFVPLNPGLETIXXXXXXXXXXXXXX 618
            I++MV +   +    T+ L VP+G + T    R W +                       
Sbjct: 943  ILIMVLVDYSIEDTYTQKLSVPSGFSVTAPEKRGWVINPLGEKSPFPVWMMVASLLPAIL 1002

Query: 619  VYIIVFMETHIAELIIAKPERRLKKGSGFHMDIVIMSFVNALCGMFGAPWQCVATVRSVS 678
            V+I++FMET I  LII+K ER L+KGSGFH+D++++  +  +C +FG PW   ATVRSV+
Sbjct: 1003 VFILIFMETQITTLIISKKERMLQKGSGFHLDLLLIVAMGGICALFGLPWLAAATVRSVT 1062

Query: 679  HVSALTIMSTTHAPGDKPHIVEVKEQRLTGLLVAVMVGISVLASGWLCLVPMAVLFGVFL 738
            H +ALT+MS   APGDKP I EVKEQR+TGLLVA++VG+S++    L  +P+AVLFG+FL
Sbjct: 1063 HANALTVMSKAVAPGDKPKIQEVKEQRVTGLLVALLVGLSIVIGDLLRQIPLAVLFGIFL 1122

Query: 739  YMGISALGGIQFWDRCILLLKPVKHHPQLPYVRRVPTLKMHMYTLIQVGGVVVLYAVKSS 798
            YMG+++L GIQF++R  LLL P KHHP + YV++V TL+MH++T +Q+  + +L+AV S+
Sbjct: 1123 YMGVTSLNGIQFYERLHLLLMPPKHHPDVTYVKKVRTLRMHLFTALQLLCLALLWAVMST 1182

Query: 799  RFSLALPFFLVLMVPLRM-SLVYIFTPLQLRALDG--AQKDIDKDDEPDFYEEAPIP 852
              SLA PF L+L VPLRM  L  IFT  +++ LD   A+   D+ +  D Y E P+P
Sbjct: 1183 AASLAFPFILILTVPLRMVVLTRIFTDREMKCLDANEAEPVFDEREGVDEYNEMPMP 1239


>X03918-1|CAA27556.1|  865|Homo sapiens HKB3 (865 aa) protein.
          Length = 865

 Score =  591 bits (1460), Expect = e-168
 Identities = 330/777 (42%), Positives = 474/777 (61%), Gaps = 51/777 (6%)

Query: 88  HNDSILKRIPDDAEATTVLVGAVGFLDQPTIAFVRLAEGIYMPSITEVPVPVRFMFILLG 147
           H   +L++IP++AEAT VLVG V FL +PT+AFVRL E + + ++ EVPVPVRF+F+LLG
Sbjct: 127 HELKLLEKIPENAEATVVLVGCVEFLSRPTMAFVRLREAVELDAVLEVPVPVRFLFLLLG 186

Query: 148 PGGADLDYHEVGRSISTLMSNPAFHSIAYKADDRRELLSAINEFLDDSIVLPPGDWERQA 207
           P  A++DYHE+GRSISTLMS+  FH  AY AD+R +LL+AIN FLD S+VLPP + + + 
Sbjct: 187 PSSANMDYHEIGRSISTLMSDKQFHEAAYLADEREDLLTAINAFLDCSVVLPPSEVQGEE 246

Query: 208 LLPLEELRAKSEMIRRRKINALERKRIVADG----DKPSDEKKALLAAEAGGMPPEEPDD 263
           LL       + +M+++R+    E+ R++  G     K + +K  L   E  G     P  
Sbjct: 247 LLR-SVAHFQRQMLKKRE----EQGRLLPTGAGLEPKSAQDKALLQMVERQGQLKMIP-- 299

Query: 264 PLSRTGRLFGGVIRDMKRRYPFYVSDFVDALNGQCVAATIFMYFAAVSSAITFGGLLAEK 323
             S  G  FGG+IRD++RRYP Y+SDF DAL+ QC+AA IF+YFAA+S AITFGGLL EK
Sbjct: 300 --SADGAAFGGLIRDVRRRYPHYLSDFRDALDPQCLAAVIFIYFAALSPAITFGGLLGEK 357

Query: 324 TYGKIGISETLSSGYVRSAVEGDLQVFTSAGGVLFALVAGQPMMITGATGPLLLLDESLA 383
           T   IG+SE + S              T+  GV+F L+  QP+++ G +GPLL+ +E+  
Sbjct: 358 TQDLIGVSELIMS--------------TALQGVVFCLLGAQPLLVIGFSGPLLVFEEAFF 403

Query: 384 NFCHSYGFDFLAARMYCGLWMIVIALCVASVEGSVAVKKITRFTEDXXXXXXXXXXXXEP 443
           +FC S   ++L  R++ G W++ +AL + ++EGS  V+ ++RFT +            E 
Sbjct: 404 SFCSSNHLEYLVGRVWIGFWLVFLALLMVALEGSFLVRFVSRFTREIFAFLISLIFIYET 463

Query: 444 ITSTIAVYRANPL-GIDYCQFREV-ALSNSTVQPLLNSTSVGNSSVVAPAPPVSRLPPQP 501
               + +++ +PL G       EV    N T      +   GN S+   +    +   QP
Sbjct: 464 FYKLVKIFQEHPLHGCSASNSSEVDGGENMTWAGARPTLGPGNRSLAGQSGQ-GKPRGQP 522

Query: 502 NTALFCTMLTLATFVLAYYLRIFRNGKFLGRSSATSRVQVTGRDGIQARRALGDFGVPIA 561
           NTA    +L   TF +A++LR F+N +F             GR     RR +GDFGVPIA
Sbjct: 523 NTAPLSLVLMAGTFFIAFFLRKFKNSRFF-----------PGR----IRRVIGDFGVPIA 567

Query: 562 IVLMVGISCLVP-VKTETLVVPAGLNPTTV--RSWFVPLNPGLETIXXXXXXXXXXXXXX 618
           I++MV +   +    T+ L VP+G + T    R W +                       
Sbjct: 568 ILIMVLVDYSIEDTYTQKLSVPSGFSVTAPEKRGWVINPLGEKSPFPVWMMVASLLPAIL 627

Query: 619 VYIIVFMETHIAELIIAKPERRLKKGSGFHMDIVIMSFVNALCGMFGAPWQCVATVRSVS 678
           V+I++FMET I  LII+K ER L+KGSGFH+D++++  +  +C +FG PW   ATVRSV+
Sbjct: 628 VFILIFMETQITTLIISKKERMLQKGSGFHLDLLLIVAMGGICALFGLPWLAAATVRSVT 687

Query: 679 HVSALTIMSTTHAPGDKPHIVEVKEQRLTGLLVAVMVGISVLASGWLCLVPMAVLFGVFL 738
           H +ALT+MS   APGDKP I EVKEQR+TGLLVA++VG+S++    L  +P+AVLFG+FL
Sbjct: 688 HANALTVMSKAVAPGDKPKIQEVKEQRVTGLLVALLVGLSIVIGDLLRQIPLAVLFGIFL 747

Query: 739 YMGISALGGIQFWDRCILLLKPVKHHPQLPYVRRVPTLKMHMYTLIQVGGVVVLYAVKSS 798
           YMG+++L GIQF++R  LLL P KHHP + YV++V TL+MH++T +Q+  + +L+AV S+
Sbjct: 748 YMGVTSLNGIQFYERLHLLLMPPKHHPDVTYVKKVRTLRMHLFTALQLLCLALLWAVMST 807

Query: 799 RFSLALPFFLVLMVPLRM-SLVYIFTPLQLRALDG--AQKDIDKDDEPDFYEEAPIP 852
             SLA PF L+L VPLRM  L  IFT  +++ LD   A+   D+ +  D Y E P+P
Sbjct: 808 AASLAFPFILILTVPLRMVVLTRIFTDREMKCLDANEAEPVFDEREGVDEYNEMPMP 864


>X12609-1|CAA31128.1|  911|Homo sapiens protein ( H.sapiens mRNA for
           red cell anion exchanger (EPB3, AE1, Band3). ).
          Length = 911

 Score =  530 bits (1307), Expect = e-149
 Identities = 311/774 (40%), Positives = 456/774 (58%), Gaps = 83/774 (10%)

Query: 88  HNDS-ILKRIPDDAEATTVLVGAVGFLDQPTIAFVRLAEGIYMPSITEVPVPVRFMFILL 146
           H+ S IL++IP D+EAT VLVG   FL+QP + FVRL E   + ++ E+PVP+RF+F+LL
Sbjct: 211 HSPSGILEKIPPDSEATLVLVGRADFLEQPVLGFVRLQEAAELEAV-ELPVPIRFLFVLL 269

Query: 147 GPGGADLDYHEVGRSISTLMSNPAFHSIAYKADDRRELLSAINEFLDDSIVLPPGDW-ER 205
           GP    +DY ++GR+ +TLMS   F   AY A  R ELL ++  FLD S+VLPP D    
Sbjct: 270 GPEAPHIDYTQLGRAAATLMSERVFRIDAYMAQSRGELLHSLEGFLDCSLVLPPTDAPSE 329

Query: 206 QALLPLEELRAKSEMIRRRKINALERKRIVADGDKPSDEKKALLAAEAGGMPPEEPDDPL 265
           QALL L  +  + E++RRR           +   KP       L    G      PDDPL
Sbjct: 330 QALLSL--VPVQRELLRRR---------YQSSPAKPDSSFYKGLDLNGG------PDDPL 372

Query: 266 SRTGRLFGGVIRDMKRRYPFYVSDFVDALNGQCVAATIFMYFAAVSSAITFGGLLAEKTY 325
            +TG+LFGG++RD++RRYP+Y+SD  DA + Q +AA IF+YFAA+S AITFGGLL EKT 
Sbjct: 373 QQTGQLFGGLVRDIRRRYPYYLSDITDAFSPQVLAAVIFIYFAALSPAITFGGLLGEKTR 432

Query: 326 GKIGISETLSSGYVRSAVEGDLQVFTSAGGVLFALVAGQPMMITGATGPLLLLDESLANF 385
            ++G+SE L S              T+  G+LFAL+  QP+++ G +GPLL+ +E+  +F
Sbjct: 433 NQMGVSELLIS--------------TAVQGILFALLGAQPLLVVGFSGPLLVFEEAFFSF 478

Query: 386 CHSYGFDFLAARMYCGLWMIVIALCVASVEGSVAVKKITRFTEDXXXXXXXXXXXXEPIT 445
           C + G +++  R++ G W+I++ + V + EGS  V+ I+R+T++            E  +
Sbjct: 479 CETNGLEYIVGRVWIGFWLILLVVLVVAFEGSFLVRFISRYTQEIFSFLISLIFIYETFS 538

Query: 446 STIAVYRANPLGIDYCQFREVALSNSTVQPLLNSTSVGNSSVVAPAPPVSRLPPQPNTAL 505
             I +++ +PL   Y         N  V             ++ P P      P PNTAL
Sbjct: 539 KLIKIFQDHPLQKTY---------NYNV-------------LMVPKPQ----GPLPNTAL 572

Query: 506 FCTMLTLATFVLAYYLRIFRNGKFLGRSSATSRVQVTGRDGIQARRALGDFGVPIAIVLM 565
              +L   TF  A  LR F+N  +             G+     RR +GDFGVPI+I++M
Sbjct: 573 LSLVLMAGTFFFAMMLRKFKNSSYF-----------PGK----LRRVIGDFGVPISILIM 617

Query: 566 VGISCLV-PVKTETLVVPAG--LNPTTVRSWFV-PLNPGLETIXXXXXXXXXXXXXXVYI 621
           V +   +    T+ L VP G  ++ ++ R W + PL    E                V+I
Sbjct: 618 VLVDFFIQDTYTQKLSVPDGFKVSNSSARGWVIHPLGLRSE-FPIWMMFASALPALLVFI 676

Query: 622 IVFMETHIAELIIAKPERRLKKGSGFHMDIVIMSFVNALCGMFGAPWQCVATVRSVSHVS 681
           ++F+E+ I  LI++KPER++ KGSGFH+D++++  +  +  +FG PW    TVRSV+H +
Sbjct: 677 LIFLESQITTLIVSKPERKMVKGSGFHLDLLLVVGMGGVAALFGMPWLSATTVRSVTHAN 736

Query: 682 ALTIMSTTHAPGDKPHIVEVKEQRLTGLLVAVMVGISVLASGWLCLVPMAVLFGVFLYMG 741
           ALT+M     PG    I EVKEQR++GLLVAV+VG+S+L    L  +P+AVLFG+FLYMG
Sbjct: 737 ALTVMGKASTPGAAAQIQEVKEQRISGLLVAVLVGLSILMEPILSRIPLAVLFGIFLYMG 796

Query: 742 ISALGGIQFWDRCILLLKPVKHHPQLPYVRRVPTLKMHMYTLIQVGGVVVLYAVKSSRFS 801
           +++L GIQ +DR +LL KP K+HP +PYV+RV T +MH++T IQ+  + VL+ VKS+  S
Sbjct: 797 VTSLSGIQLFDRILLLFKPPKYHPDVPYVKRVKTWRMHLFTGIQIICLAVLWVVKSTPAS 856

Query: 802 LALPFFLVLMVPLRMSLV-YIFTPLQLRALDG--AQKDIDKDDEPDFYEEAPIP 852
           LALPF L+L VPLR  L+  IF  ++L+ LD   A+   D+++  D Y+E  +P
Sbjct: 857 LALPFVLILTVPLRRVLLPLIFRNVELQCLDADDAKATFDEEEGRDEYDEVAMP 910


>M27819-1|AAA35514.1|  911|Homo sapiens protein ( Human anion
           exchange protein 1 (AE1, band 3) mRNA, complete cds. ).
          Length = 911

 Score =  530 bits (1307), Expect = e-149
 Identities = 311/774 (40%), Positives = 456/774 (58%), Gaps = 83/774 (10%)

Query: 88  HNDS-ILKRIPDDAEATTVLVGAVGFLDQPTIAFVRLAEGIYMPSITEVPVPVRFMFILL 146
           H+ S IL++IP D+EAT VLVG   FL+QP + FVRL E   + ++ E+PVP+RF+F+LL
Sbjct: 211 HSPSGILEKIPPDSEATLVLVGRADFLEQPVLGFVRLQEAAELEAV-ELPVPIRFLFVLL 269

Query: 147 GPGGADLDYHEVGRSISTLMSNPAFHSIAYKADDRRELLSAINEFLDDSIVLPPGDW-ER 205
           GP    +DY ++GR+ +TLMS   F   AY A  R ELL ++  FLD S+VLPP D    
Sbjct: 270 GPEAPHIDYTQLGRAAATLMSERVFRIDAYMAQSRGELLHSLEGFLDCSLVLPPTDAPSE 329

Query: 206 QALLPLEELRAKSEMIRRRKINALERKRIVADGDKPSDEKKALLAAEAGGMPPEEPDDPL 265
           QALL L  +  + E++RRR           +   KP       L    G      PDDPL
Sbjct: 330 QALLSL--VPVQRELLRRR---------YQSSPAKPDSSFYKGLDLNGG------PDDPL 372

Query: 266 SRTGRLFGGVIRDMKRRYPFYVSDFVDALNGQCVAATIFMYFAAVSSAITFGGLLAEKTY 325
            +TG+LFGG++RD++RRYP+Y+SD  DA + Q +AA IF+YFAA+S AITFGGLL EKT 
Sbjct: 373 QQTGQLFGGLVRDIRRRYPYYLSDITDAFSPQVLAAVIFIYFAALSPAITFGGLLGEKTR 432

Query: 326 GKIGISETLSSGYVRSAVEGDLQVFTSAGGVLFALVAGQPMMITGATGPLLLLDESLANF 385
            ++G+SE L S              T+  G+LFAL+  QP+++ G +GPLL+ +E+  +F
Sbjct: 433 NQMGVSELLIS--------------TAVQGILFALLGAQPLLVVGFSGPLLVFEEAFFSF 478

Query: 386 CHSYGFDFLAARMYCGLWMIVIALCVASVEGSVAVKKITRFTEDXXXXXXXXXXXXEPIT 445
           C + G +++  R++ G W+I++ + V + EGS  V+ I+R+T++            E  +
Sbjct: 479 CETNGLEYIVGRVWIGFWLILLVVLVVAFEGSFLVRFISRYTQEIFSFLISLIFIYETFS 538

Query: 446 STIAVYRANPLGIDYCQFREVALSNSTVQPLLNSTSVGNSSVVAPAPPVSRLPPQPNTAL 505
             I +++ +PL   Y         N  V             ++ P P      P PNTAL
Sbjct: 539 KLIKIFQDHPLQKTY---------NYNV-------------LMVPKPQ----GPLPNTAL 572

Query: 506 FCTMLTLATFVLAYYLRIFRNGKFLGRSSATSRVQVTGRDGIQARRALGDFGVPIAIVLM 565
              +L   TF  A  LR F+N  +             G+     RR +GDFGVPI+I++M
Sbjct: 573 LSLVLMAGTFFFAMMLRKFKNSSYF-----------PGK----LRRVIGDFGVPISILIM 617

Query: 566 VGISCLV-PVKTETLVVPAG--LNPTTVRSWFV-PLNPGLETIXXXXXXXXXXXXXXVYI 621
           V +   +    T+ L VP G  ++ ++ R W + PL    E                V+I
Sbjct: 618 VLVDFFIQDTYTQKLSVPDGFKVSNSSARGWVIHPLGLRSE-FPIWMMFASALPALLVFI 676

Query: 622 IVFMETHIAELIIAKPERRLKKGSGFHMDIVIMSFVNALCGMFGAPWQCVATVRSVSHVS 681
           ++F+E+ I  LI++KPER++ KGSGFH+D++++  +  +  +FG PW    TVRSV+H +
Sbjct: 677 LIFLESQITTLIVSKPERKMVKGSGFHLDLLLVVGMGGVAALFGMPWLSATTVRSVTHAN 736

Query: 682 ALTIMSTTHAPGDKPHIVEVKEQRLTGLLVAVMVGISVLASGWLCLVPMAVLFGVFLYMG 741
           ALT+M     PG    I EVKEQR++GLLVAV+VG+S+L    L  +P+AVLFG+FLYMG
Sbjct: 737 ALTVMGKASTPGAAAQIQEVKEQRISGLLVAVLVGLSILMEPILSRIPLAVLFGIFLYMG 796

Query: 742 ISALGGIQFWDRCILLLKPVKHHPQLPYVRRVPTLKMHMYTLIQVGGVVVLYAVKSSRFS 801
           +++L GIQ +DR +LL KP K+HP +PYV+RV T +MH++T IQ+  + VL+ VKS+  S
Sbjct: 797 VTSLSGIQLFDRILLLFKPPKYHPDVPYVKRVKTWRMHLFTGIQIICLAVLWVVKSTPAS 856

Query: 802 LALPFFLVLMVPLRMSLV-YIFTPLQLRALDG--AQKDIDKDDEPDFYEEAPIP 852
           LALPF L+L VPLR  L+  IF  ++L+ LD   A+   D+++  D Y+E  +P
Sbjct: 857 LALPFVLILTVPLRRVLLPLIFRNVELQCLDADDAKATFDEEEGRDEYDEVAMP 910


>DQ072115-1|AAY57324.1|  911|Homo sapiens solute carrier family 4,
           anion exchanger, member 1 (erythrocyte membrane protei
           protein.
          Length = 911

 Score =  530 bits (1307), Expect = e-149
 Identities = 311/774 (40%), Positives = 456/774 (58%), Gaps = 83/774 (10%)

Query: 88  HNDS-ILKRIPDDAEATTVLVGAVGFLDQPTIAFVRLAEGIYMPSITEVPVPVRFMFILL 146
           H+ S IL++IP D+EAT VLVG   FL+QP + FVRL E   + ++ E+PVP+RF+F+LL
Sbjct: 211 HSPSGILEKIPPDSEATLVLVGRADFLEQPVLGFVRLQEAAELEAV-ELPVPIRFLFVLL 269

Query: 147 GPGGADLDYHEVGRSISTLMSNPAFHSIAYKADDRRELLSAINEFLDDSIVLPPGDW-ER 205
           GP    +DY ++GR+ +TLMS   F   AY A  R ELL ++  FLD S+VLPP D    
Sbjct: 270 GPEAPHIDYTQLGRAAATLMSERVFRIDAYMAQSRGELLHSLEGFLDCSLVLPPTDAPSE 329

Query: 206 QALLPLEELRAKSEMIRRRKINALERKRIVADGDKPSDEKKALLAAEAGGMPPEEPDDPL 265
           QALL L  +  + E++RRR           +   KP       L    G      PDDPL
Sbjct: 330 QALLSL--VPVQRELLRRR---------YQSSPAKPDSSFYKGLDLNGG------PDDPL 372

Query: 266 SRTGRLFGGVIRDMKRRYPFYVSDFVDALNGQCVAATIFMYFAAVSSAITFGGLLAEKTY 325
            +TG+LFGG++RD++RRYP+Y+SD  DA + Q +AA IF+YFAA+S AITFGGLL EKT 
Sbjct: 373 QQTGQLFGGLVRDIRRRYPYYLSDITDAFSPQVLAAVIFIYFAALSPAITFGGLLGEKTR 432

Query: 326 GKIGISETLSSGYVRSAVEGDLQVFTSAGGVLFALVAGQPMMITGATGPLLLLDESLANF 385
            ++G+SE L S              T+  G+LFAL+  QP+++ G +GPLL+ +E+  +F
Sbjct: 433 NQMGVSELLIS--------------TAVQGILFALLGAQPLLVVGFSGPLLVFEEAFFSF 478

Query: 386 CHSYGFDFLAARMYCGLWMIVIALCVASVEGSVAVKKITRFTEDXXXXXXXXXXXXEPIT 445
           C + G +++  R++ G W+I++ + V + EGS  V+ I+R+T++            E  +
Sbjct: 479 CETNGLEYIVGRVWIGFWLILLVVLVVAFEGSFLVRFISRYTQEIFSFLISLIFIYETFS 538

Query: 446 STIAVYRANPLGIDYCQFREVALSNSTVQPLLNSTSVGNSSVVAPAPPVSRLPPQPNTAL 505
             I +++ +PL   Y         N  V             ++ P P      P PNTAL
Sbjct: 539 KLIKIFQDHPLQKTY---------NYNV-------------LMVPKPQ----GPLPNTAL 572

Query: 506 FCTMLTLATFVLAYYLRIFRNGKFLGRSSATSRVQVTGRDGIQARRALGDFGVPIAIVLM 565
              +L   TF  A  LR F+N  +             G+     RR +GDFGVPI+I++M
Sbjct: 573 LSLVLMAGTFFFAMMLRKFKNSSYF-----------PGK----LRRVIGDFGVPISILIM 617

Query: 566 VGISCLV-PVKTETLVVPAG--LNPTTVRSWFV-PLNPGLETIXXXXXXXXXXXXXXVYI 621
           V +   +    T+ L VP G  ++ ++ R W + PL    E                V+I
Sbjct: 618 VLVDFFIQDTYTQKLSVPDGFKVSNSSARGWVIHPLGLRSE-FPIWMMFASALPALLVFI 676

Query: 622 IVFMETHIAELIIAKPERRLKKGSGFHMDIVIMSFVNALCGMFGAPWQCVATVRSVSHVS 681
           ++F+E+ I  LI++KPER++ KGSGFH+D++++  +  +  +FG PW    TVRSV+H +
Sbjct: 677 LIFLESQITTLIVSKPERKMVKGSGFHLDLLLVVGMGGVAALFGMPWLSATTVRSVTHAN 736

Query: 682 ALTIMSTTHAPGDKPHIVEVKEQRLTGLLVAVMVGISVLASGWLCLVPMAVLFGVFLYMG 741
           ALT+M     PG    I EVKEQR++GLLVAV+VG+S+L    L  +P+AVLFG+FLYMG
Sbjct: 737 ALTVMGKASTPGAAAQIQEVKEQRISGLLVAVLVGLSILMEPILSRIPLAVLFGIFLYMG 796

Query: 742 ISALGGIQFWDRCILLLKPVKHHPQLPYVRRVPTLKMHMYTLIQVGGVVVLYAVKSSRFS 801
           +++L GIQ +DR +LL KP K+HP +PYV+RV T +MH++T IQ+  + VL+ VKS+  S
Sbjct: 797 VTSLSGIQLFDRILLLFKPPKYHPDVPYVKRVKTWRMHLFTGIQIICLAVLWVVKSTPAS 856

Query: 802 LALPFFLVLMVPLRMSLV-YIFTPLQLRALDG--AQKDIDKDDEPDFYEEAPIP 852
           LALPF L+L VPLR  L+  IF  ++L+ LD   A+   D+++  D Y+E  +P
Sbjct: 857 LALPFVLILTVPLRRVLLPLIFRNVELQCLDADDAKATFDEEEGRDEYDEVAMP 910


>BC101574-1|AAI01575.1|  911|Homo sapiens solute carrier family 4,
           anion exchanger, member 1 (erythrocyte membrane protei
           protein.
          Length = 911

 Score =  530 bits (1307), Expect = e-149
 Identities = 311/774 (40%), Positives = 456/774 (58%), Gaps = 83/774 (10%)

Query: 88  HNDS-ILKRIPDDAEATTVLVGAVGFLDQPTIAFVRLAEGIYMPSITEVPVPVRFMFILL 146
           H+ S IL++IP D+EAT VLVG   FL+QP + FVRL E   + ++ E+PVP+RF+F+LL
Sbjct: 211 HSPSGILEKIPPDSEATLVLVGRADFLEQPVLGFVRLQEAAELEAV-ELPVPIRFLFVLL 269

Query: 147 GPGGADLDYHEVGRSISTLMSNPAFHSIAYKADDRRELLSAINEFLDDSIVLPPGDW-ER 205
           GP    +DY ++GR+ +TLMS   F   AY A  R ELL ++  FLD S+VLPP D    
Sbjct: 270 GPEAPHIDYTQLGRAAATLMSERVFRIDAYMAQSRGELLHSLEGFLDCSLVLPPTDAPSE 329

Query: 206 QALLPLEELRAKSEMIRRRKINALERKRIVADGDKPSDEKKALLAAEAGGMPPEEPDDPL 265
           QALL L  +  + E++RRR           +   KP       L    G      PDDPL
Sbjct: 330 QALLSL--VPVQRELLRRR---------YQSSPAKPDSSFYKGLDLNGG------PDDPL 372

Query: 266 SRTGRLFGGVIRDMKRRYPFYVSDFVDALNGQCVAATIFMYFAAVSSAITFGGLLAEKTY 325
            +TG+LFGG++RD++RRYP+Y+SD  DA + Q +AA IF+YFAA+S AITFGGLL EKT 
Sbjct: 373 QQTGQLFGGLVRDIRRRYPYYLSDITDAFSPQVLAAVIFIYFAALSPAITFGGLLGEKTR 432

Query: 326 GKIGISETLSSGYVRSAVEGDLQVFTSAGGVLFALVAGQPMMITGATGPLLLLDESLANF 385
            ++G+SE L S              T+  G+LFAL+  QP+++ G +GPLL+ +E+  +F
Sbjct: 433 NQMGVSELLIS--------------TAVQGILFALLGAQPLLVVGFSGPLLVFEEAFFSF 478

Query: 386 CHSYGFDFLAARMYCGLWMIVIALCVASVEGSVAVKKITRFTEDXXXXXXXXXXXXEPIT 445
           C + G +++  R++ G W+I++ + V + EGS  V+ I+R+T++            E  +
Sbjct: 479 CETNGLEYIVGRVWIGFWLILLVVLVVAFEGSFLVRFISRYTQEIFSFLISLIFIYETFS 538

Query: 446 STIAVYRANPLGIDYCQFREVALSNSTVQPLLNSTSVGNSSVVAPAPPVSRLPPQPNTAL 505
             I +++ +PL   Y         N  V             ++ P P      P PNTAL
Sbjct: 539 KLIKIFQDHPLQKTY---------NYNV-------------LMVPKPQ----GPLPNTAL 572

Query: 506 FCTMLTLATFVLAYYLRIFRNGKFLGRSSATSRVQVTGRDGIQARRALGDFGVPIAIVLM 565
              +L   TF  A  LR F+N  +             G+     RR +GDFGVPI+I++M
Sbjct: 573 LSLVLMAGTFFFAMMLRKFKNSSYF-----------PGK----LRRVIGDFGVPISILIM 617

Query: 566 VGISCLV-PVKTETLVVPAG--LNPTTVRSWFV-PLNPGLETIXXXXXXXXXXXXXXVYI 621
           V +   +    T+ L VP G  ++ ++ R W + PL    E                V+I
Sbjct: 618 VLVDFFIQDTYTQKLSVPDGFKVSNSSARGWVIHPLGLRSE-FPIWMMFASALPALLVFI 676

Query: 622 IVFMETHIAELIIAKPERRLKKGSGFHMDIVIMSFVNALCGMFGAPWQCVATVRSVSHVS 681
           ++F+E+ I  LI++KPER++ KGSGFH+D++++  +  +  +FG PW    TVRSV+H +
Sbjct: 677 LIFLESQITTLIVSKPERKMVKGSGFHLDLLLVVGMGGVAALFGMPWLSATTVRSVTHAN 736

Query: 682 ALTIMSTTHAPGDKPHIVEVKEQRLTGLLVAVMVGISVLASGWLCLVPMAVLFGVFLYMG 741
           ALT+M     PG    I EVKEQR++GLLVAV+VG+S+L    L  +P+AVLFG+FLYMG
Sbjct: 737 ALTVMGKASTPGAAAQIQEVKEQRISGLLVAVLVGLSILMEPILSRIPLAVLFGIFLYMG 796

Query: 742 ISALGGIQFWDRCILLLKPVKHHPQLPYVRRVPTLKMHMYTLIQVGGVVVLYAVKSSRFS 801
           +++L GIQ +DR +LL KP K+HP +PYV+RV T +MH++T IQ+  + VL+ VKS+  S
Sbjct: 797 VTSLSGIQLFDRILLLFKPPKYHPDVPYVKRVKTWRMHLFTGIQIICLAVLWVVKSTPAS 856

Query: 802 LALPFFLVLMVPLRMSLV-YIFTPLQLRALDG--AQKDIDKDDEPDFYEEAPIP 852
           LALPF L+L VPLR  L+  IF  ++L+ LD   A+   D+++  D Y+E  +P
Sbjct: 857 LALPFVLILTVPLRRVLLPLIFRNVELQCLDADDAKATFDEEEGRDEYDEVAMP 910


>BC101570-1|AAI01571.1|  911|Homo sapiens solute carrier family 4,
           anion exchanger, member 1 (erythrocyte membrane protei
           protein.
          Length = 911

 Score =  530 bits (1307), Expect = e-149
 Identities = 311/774 (40%), Positives = 456/774 (58%), Gaps = 83/774 (10%)

Query: 88  HNDS-ILKRIPDDAEATTVLVGAVGFLDQPTIAFVRLAEGIYMPSITEVPVPVRFMFILL 146
           H+ S IL++IP D+EAT VLVG   FL+QP + FVRL E   + ++ E+PVP+RF+F+LL
Sbjct: 211 HSPSGILEKIPPDSEATLVLVGRADFLEQPVLGFVRLQEAAELEAV-ELPVPIRFLFVLL 269

Query: 147 GPGGADLDYHEVGRSISTLMSNPAFHSIAYKADDRRELLSAINEFLDDSIVLPPGDW-ER 205
           GP    +DY ++GR+ +TLMS   F   AY A  R ELL ++  FLD S+VLPP D    
Sbjct: 270 GPEAPHIDYTQLGRAAATLMSERVFRIDAYMAQSRGELLHSLEGFLDCSLVLPPTDAPSE 329

Query: 206 QALLPLEELRAKSEMIRRRKINALERKRIVADGDKPSDEKKALLAAEAGGMPPEEPDDPL 265
           QALL L  +  + E++RRR           +   KP       L    G      PDDPL
Sbjct: 330 QALLSL--VPVQRELLRRR---------YQSSPAKPDSSFYKGLDLNGG------PDDPL 372

Query: 266 SRTGRLFGGVIRDMKRRYPFYVSDFVDALNGQCVAATIFMYFAAVSSAITFGGLLAEKTY 325
            +TG+LFGG++RD++RRYP+Y+SD  DA + Q +AA IF+YFAA+S AITFGGLL EKT 
Sbjct: 373 QQTGQLFGGLVRDIRRRYPYYLSDITDAFSPQVLAAVIFIYFAALSPAITFGGLLGEKTR 432

Query: 326 GKIGISETLSSGYVRSAVEGDLQVFTSAGGVLFALVAGQPMMITGATGPLLLLDESLANF 385
            ++G+SE L S              T+  G+LFAL+  QP+++ G +GPLL+ +E+  +F
Sbjct: 433 NQMGVSELLIS--------------TAVQGILFALLGAQPLLVVGFSGPLLVFEEAFFSF 478

Query: 386 CHSYGFDFLAARMYCGLWMIVIALCVASVEGSVAVKKITRFTEDXXXXXXXXXXXXEPIT 445
           C + G +++  R++ G W+I++ + V + EGS  V+ I+R+T++            E  +
Sbjct: 479 CETNGLEYIVGRVWIGFWLILLVVLVVAFEGSFLVRFISRYTQEIFSFLISLIFIYETFS 538

Query: 446 STIAVYRANPLGIDYCQFREVALSNSTVQPLLNSTSVGNSSVVAPAPPVSRLPPQPNTAL 505
             I +++ +PL   Y         N  V             ++ P P      P PNTAL
Sbjct: 539 KLIKIFQDHPLQKTY---------NYNV-------------LMVPKPQ----GPLPNTAL 572

Query: 506 FCTMLTLATFVLAYYLRIFRNGKFLGRSSATSRVQVTGRDGIQARRALGDFGVPIAIVLM 565
              +L   TF  A  LR F+N  +             G+     RR +GDFGVPI+I++M
Sbjct: 573 LSLVLMAGTFFFAMMLRKFKNSSYF-----------PGK----LRRVIGDFGVPISILIM 617

Query: 566 VGISCLV-PVKTETLVVPAG--LNPTTVRSWFV-PLNPGLETIXXXXXXXXXXXXXXVYI 621
           V +   +    T+ L VP G  ++ ++ R W + PL    E                V+I
Sbjct: 618 VLVDFFIQDTYTQKLSVPDGFKVSNSSARGWVIHPLGLRSE-FPIWMMFASALPALLVFI 676

Query: 622 IVFMETHIAELIIAKPERRLKKGSGFHMDIVIMSFVNALCGMFGAPWQCVATVRSVSHVS 681
           ++F+E+ I  LI++KPER++ KGSGFH+D++++  +  +  +FG PW    TVRSV+H +
Sbjct: 677 LIFLESQITTLIVSKPERKMVKGSGFHLDLLLVVGMGGVAALFGMPWLSATTVRSVTHAN 736

Query: 682 ALTIMSTTHAPGDKPHIVEVKEQRLTGLLVAVMVGISVLASGWLCLVPMAVLFGVFLYMG 741
           ALT+M     PG    I EVKEQR++GLLVAV+VG+S+L    L  +P+AVLFG+FLYMG
Sbjct: 737 ALTVMGKASTPGAAAQIQEVKEQRISGLLVAVLVGLSILMEPILSRIPLAVLFGIFLYMG 796

Query: 742 ISALGGIQFWDRCILLLKPVKHHPQLPYVRRVPTLKMHMYTLIQVGGVVVLYAVKSSRFS 801
           +++L GIQ +DR +LL KP K+HP +PYV+RV T +MH++T IQ+  + VL+ VKS+  S
Sbjct: 797 VTSLSGIQLFDRILLLFKPPKYHPDVPYVKRVKTWRMHLFTGIQIICLAVLWVVKSTPAS 856

Query: 802 LALPFFLVLMVPLRMSLV-YIFTPLQLRALDG--AQKDIDKDDEPDFYEEAPIP 852
           LALPF L+L VPLR  L+  IF  ++L+ LD   A+   D+++  D Y+E  +P
Sbjct: 857 LALPFVLILTVPLRRVLLPLIFRNVELQCLDADDAKATFDEEEGRDEYDEVAMP 910


>BC099629-1|AAH99629.1|  911|Homo sapiens solute carrier family 4,
           anion exchanger, member 1 (erythrocyte membrane protei
           protein.
          Length = 911

 Score =  530 bits (1307), Expect = e-149
 Identities = 311/774 (40%), Positives = 456/774 (58%), Gaps = 83/774 (10%)

Query: 88  HNDS-ILKRIPDDAEATTVLVGAVGFLDQPTIAFVRLAEGIYMPSITEVPVPVRFMFILL 146
           H+ S IL++IP D+EAT VLVG   FL+QP + FVRL E   + ++ E+PVP+RF+F+LL
Sbjct: 211 HSPSGILEKIPPDSEATLVLVGRADFLEQPVLGFVRLQEAAELEAV-ELPVPIRFLFVLL 269

Query: 147 GPGGADLDYHEVGRSISTLMSNPAFHSIAYKADDRRELLSAINEFLDDSIVLPPGDW-ER 205
           GP    +DY ++GR+ +TLMS   F   AY A  R ELL ++  FLD S+VLPP D    
Sbjct: 270 GPEAPHIDYTQLGRAAATLMSERVFRIDAYMAQSRGELLHSLEGFLDCSLVLPPTDAPSE 329

Query: 206 QALLPLEELRAKSEMIRRRKINALERKRIVADGDKPSDEKKALLAAEAGGMPPEEPDDPL 265
           QALL L  +  + E++RRR           +   KP       L    G      PDDPL
Sbjct: 330 QALLSL--VPVQRELLRRR---------YQSSPAKPDSSFYKGLDLNGG------PDDPL 372

Query: 266 SRTGRLFGGVIRDMKRRYPFYVSDFVDALNGQCVAATIFMYFAAVSSAITFGGLLAEKTY 325
            +TG+LFGG++RD++RRYP+Y+SD  DA + Q +AA IF+YFAA+S AITFGGLL EKT 
Sbjct: 373 QQTGQLFGGLVRDIRRRYPYYLSDITDAFSPQVLAAVIFIYFAALSPAITFGGLLGEKTR 432

Query: 326 GKIGISETLSSGYVRSAVEGDLQVFTSAGGVLFALVAGQPMMITGATGPLLLLDESLANF 385
            ++G+SE L S              T+  G+LFAL+  QP+++ G +GPLL+ +E+  +F
Sbjct: 433 NQMGVSELLIS--------------TAVQGILFALLGAQPLLVVGFSGPLLVFEEAFFSF 478

Query: 386 CHSYGFDFLAARMYCGLWMIVIALCVASVEGSVAVKKITRFTEDXXXXXXXXXXXXEPIT 445
           C + G +++  R++ G W+I++ + V + EGS  V+ I+R+T++            E  +
Sbjct: 479 CETNGLEYIVGRVWIGFWLILLVVLVVAFEGSFLVRFISRYTQEIFSFLISLIFIYETFS 538

Query: 446 STIAVYRANPLGIDYCQFREVALSNSTVQPLLNSTSVGNSSVVAPAPPVSRLPPQPNTAL 505
             I +++ +PL   Y         N  V             ++ P P      P PNTAL
Sbjct: 539 KLIKIFQDHPLQKTY---------NYNV-------------LMVPKPQ----GPLPNTAL 572

Query: 506 FCTMLTLATFVLAYYLRIFRNGKFLGRSSATSRVQVTGRDGIQARRALGDFGVPIAIVLM 565
              +L   TF  A  LR F+N  +             G+     RR +GDFGVPI+I++M
Sbjct: 573 LSLVLMAGTFFFAMMLRKFKNSSYF-----------PGK----LRRVIGDFGVPISILIM 617

Query: 566 VGISCLV-PVKTETLVVPAG--LNPTTVRSWFV-PLNPGLETIXXXXXXXXXXXXXXVYI 621
           V +   +    T+ L VP G  ++ ++ R W + PL    E                V+I
Sbjct: 618 VLVDFFIQDTYTQKLSVPDGFKVSNSSARGWVIHPLGLRSE-FPIWMMFASALPALLVFI 676

Query: 622 IVFMETHIAELIIAKPERRLKKGSGFHMDIVIMSFVNALCGMFGAPWQCVATVRSVSHVS 681
           ++F+E+ I  LI++KPER++ KGSGFH+D++++  +  +  +FG PW    TVRSV+H +
Sbjct: 677 LIFLESQITTLIVSKPERKMVKGSGFHLDLLLVVGMGGVAALFGMPWLSATTVRSVTHAN 736

Query: 682 ALTIMSTTHAPGDKPHIVEVKEQRLTGLLVAVMVGISVLASGWLCLVPMAVLFGVFLYMG 741
           ALT+M     PG    I EVKEQR++GLLVAV+VG+S+L    L  +P+AVLFG+FLYMG
Sbjct: 737 ALTVMGKASTPGAAAQIQEVKEQRISGLLVAVLVGLSILMEPILSRIPLAVLFGIFLYMG 796

Query: 742 ISALGGIQFWDRCILLLKPVKHHPQLPYVRRVPTLKMHMYTLIQVGGVVVLYAVKSSRFS 801
           +++L GIQ +DR +LL KP K+HP +PYV+RV T +MH++T IQ+  + VL+ VKS+  S
Sbjct: 797 VTSLSGIQLFDRILLLFKPPKYHPDVPYVKRVKTWRMHLFTGIQIICLAVLWVVKSTPAS 856

Query: 802 LALPFFLVLMVPLRMSLV-YIFTPLQLRALDG--AQKDIDKDDEPDFYEEAPIP 852
           LALPF L+L VPLR  L+  IF  ++L+ LD   A+   D+++  D Y+E  +P
Sbjct: 857 LALPFVLILTVPLRRVLLPLIFRNVELQCLDADDAKATFDEEEGRDEYDEVAMP 910


>BC099628-1|AAH99628.1|  911|Homo sapiens solute carrier family 4,
           anion exchanger, member 1 (erythrocyte membrane protei
           protein.
          Length = 911

 Score =  530 bits (1307), Expect = e-149
 Identities = 311/774 (40%), Positives = 456/774 (58%), Gaps = 83/774 (10%)

Query: 88  HNDS-ILKRIPDDAEATTVLVGAVGFLDQPTIAFVRLAEGIYMPSITEVPVPVRFMFILL 146
           H+ S IL++IP D+EAT VLVG   FL+QP + FVRL E   + ++ E+PVP+RF+F+LL
Sbjct: 211 HSPSGILEKIPPDSEATLVLVGRADFLEQPVLGFVRLQEAAELEAV-ELPVPIRFLFVLL 269

Query: 147 GPGGADLDYHEVGRSISTLMSNPAFHSIAYKADDRRELLSAINEFLDDSIVLPPGDW-ER 205
           GP    +DY ++GR+ +TLMS   F   AY A  R ELL ++  FLD S+VLPP D    
Sbjct: 270 GPEAPHIDYTQLGRAAATLMSERVFRIDAYMAQSRGELLHSLEGFLDCSLVLPPTDAPSE 329

Query: 206 QALLPLEELRAKSEMIRRRKINALERKRIVADGDKPSDEKKALLAAEAGGMPPEEPDDPL 265
           QALL L  +  + E++RRR           +   KP       L    G      PDDPL
Sbjct: 330 QALLSL--VPVQRELLRRR---------YQSSPAKPDSSFYKGLDLNGG------PDDPL 372

Query: 266 SRTGRLFGGVIRDMKRRYPFYVSDFVDALNGQCVAATIFMYFAAVSSAITFGGLLAEKTY 325
            +TG+LFGG++RD++RRYP+Y+SD  DA + Q +AA IF+YFAA+S AITFGGLL EKT 
Sbjct: 373 QQTGQLFGGLVRDIRRRYPYYLSDITDAFSPQVLAAVIFIYFAALSPAITFGGLLGEKTR 432

Query: 326 GKIGISETLSSGYVRSAVEGDLQVFTSAGGVLFALVAGQPMMITGATGPLLLLDESLANF 385
            ++G+SE L S              T+  G+LFAL+  QP+++ G +GPLL+ +E+  +F
Sbjct: 433 NQMGVSELLIS--------------TAVQGILFALLGAQPLLVVGFSGPLLVFEEAFFSF 478

Query: 386 CHSYGFDFLAARMYCGLWMIVIALCVASVEGSVAVKKITRFTEDXXXXXXXXXXXXEPIT 445
           C + G +++  R++ G W+I++ + V + EGS  V+ I+R+T++            E  +
Sbjct: 479 CETNGLEYIVGRVWIGFWLILLVVLVVAFEGSFLVRFISRYTQEIFSFLISLIFIYETFS 538

Query: 446 STIAVYRANPLGIDYCQFREVALSNSTVQPLLNSTSVGNSSVVAPAPPVSRLPPQPNTAL 505
             I +++ +PL   Y         N  V             ++ P P      P PNTAL
Sbjct: 539 KLIKIFQDHPLQKTY---------NYNV-------------LMVPKPQ----GPLPNTAL 572

Query: 506 FCTMLTLATFVLAYYLRIFRNGKFLGRSSATSRVQVTGRDGIQARRALGDFGVPIAIVLM 565
              +L   TF  A  LR F+N  +             G+     RR +GDFGVPI+I++M
Sbjct: 573 LSLVLMAGTFFFAMMLRKFKNSSYF-----------PGK----LRRVIGDFGVPISILIM 617

Query: 566 VGISCLV-PVKTETLVVPAG--LNPTTVRSWFV-PLNPGLETIXXXXXXXXXXXXXXVYI 621
           V +   +    T+ L VP G  ++ ++ R W + PL    E                V+I
Sbjct: 618 VLVDFFIQDTYTQKLSVPDGFKVSNSSARGWVIHPLGLRSE-FPIWMMFASALPALLVFI 676

Query: 622 IVFMETHIAELIIAKPERRLKKGSGFHMDIVIMSFVNALCGMFGAPWQCVATVRSVSHVS 681
           ++F+E+ I  LI++KPER++ KGSGFH+D++++  +  +  +FG PW    TVRSV+H +
Sbjct: 677 LIFLESQITTLIVSKPERKMVKGSGFHLDLLLVVGMGGVAALFGMPWLSATTVRSVTHAN 736

Query: 682 ALTIMSTTHAPGDKPHIVEVKEQRLTGLLVAVMVGISVLASGWLCLVPMAVLFGVFLYMG 741
           ALT+M     PG    I EVKEQR++GLLVAV+VG+S+L    L  +P+AVLFG+FLYMG
Sbjct: 737 ALTVMGKASTPGAAAQIQEVKEQRISGLLVAVLVGLSILMEPILSRIPLAVLFGIFLYMG 796

Query: 742 ISALGGIQFWDRCILLLKPVKHHPQLPYVRRVPTLKMHMYTLIQVGGVVVLYAVKSSRFS 801
           +++L GIQ +DR +LL KP K+HP +PYV+RV T +MH++T IQ+  + VL+ VKS+  S
Sbjct: 797 VTSLSGIQLFDRILLLFKPPKYHPDVPYVKRVKTWRMHLFTGIQIICLAVLWVVKSTPAS 856

Query: 802 LALPFFLVLMVPLRMSLV-YIFTPLQLRALDG--AQKDIDKDDEPDFYEEAPIP 852
           LALPF L+L VPLR  L+  IF  ++L+ LD   A+   D+++  D Y+E  +P
Sbjct: 857 LALPFVLILTVPLRRVLLPLIFRNVELQCLDADDAKATFDEEEGRDEYDEVAMP 910


>BC096107-1|AAH96107.1|  911|Homo sapiens solute carrier family 4,
           anion exchanger, member 1 (erythrocyte membrane protei
           protein.
          Length = 911

 Score =  530 bits (1307), Expect = e-149
 Identities = 311/774 (40%), Positives = 456/774 (58%), Gaps = 83/774 (10%)

Query: 88  HNDS-ILKRIPDDAEATTVLVGAVGFLDQPTIAFVRLAEGIYMPSITEVPVPVRFMFILL 146
           H+ S IL++IP D+EAT VLVG   FL+QP + FVRL E   + ++ E+PVP+RF+F+LL
Sbjct: 211 HSPSGILEKIPPDSEATLVLVGRADFLEQPVLGFVRLQEAAELEAV-ELPVPIRFLFVLL 269

Query: 147 GPGGADLDYHEVGRSISTLMSNPAFHSIAYKADDRRELLSAINEFLDDSIVLPPGDW-ER 205
           GP    +DY ++GR+ +TLMS   F   AY A  R ELL ++  FLD S+VLPP D    
Sbjct: 270 GPEAPHIDYTQLGRAAATLMSERVFRIDAYMAQSRGELLHSLEGFLDCSLVLPPTDAPSE 329

Query: 206 QALLPLEELRAKSEMIRRRKINALERKRIVADGDKPSDEKKALLAAEAGGMPPEEPDDPL 265
           QALL L  +  + E++RRR           +   KP       L    G      PDDPL
Sbjct: 330 QALLSL--VPVQRELLRRR---------YQSSPAKPDSSFYKGLDLNGG------PDDPL 372

Query: 266 SRTGRLFGGVIRDMKRRYPFYVSDFVDALNGQCVAATIFMYFAAVSSAITFGGLLAEKTY 325
            +TG+LFGG++RD++RRYP+Y+SD  DA + Q +AA IF+YFAA+S AITFGGLL EKT 
Sbjct: 373 QQTGQLFGGLVRDIRRRYPYYLSDITDAFSPQVLAAVIFIYFAALSPAITFGGLLGEKTR 432

Query: 326 GKIGISETLSSGYVRSAVEGDLQVFTSAGGVLFALVAGQPMMITGATGPLLLLDESLANF 385
            ++G+SE L S              T+  G+LFAL+  QP+++ G +GPLL+ +E+  +F
Sbjct: 433 NQMGVSELLIS--------------TAVQGILFALLGAQPLLVVGFSGPLLVFEEAFFSF 478

Query: 386 CHSYGFDFLAARMYCGLWMIVIALCVASVEGSVAVKKITRFTEDXXXXXXXXXXXXEPIT 445
           C + G +++  R++ G W+I++ + V + EGS  V+ I+R+T++            E  +
Sbjct: 479 CETNGLEYIVGRVWIGFWLILLVVLVVAFEGSFLVRFISRYTQEIFSFLISLIFIYETFS 538

Query: 446 STIAVYRANPLGIDYCQFREVALSNSTVQPLLNSTSVGNSSVVAPAPPVSRLPPQPNTAL 505
             I +++ +PL   Y         N  V             ++ P P      P PNTAL
Sbjct: 539 KLIKIFQDHPLQKTY---------NYNV-------------LMVPKPQ----GPLPNTAL 572

Query: 506 FCTMLTLATFVLAYYLRIFRNGKFLGRSSATSRVQVTGRDGIQARRALGDFGVPIAIVLM 565
              +L   TF  A  LR F+N  +             G+     RR +GDFGVPI+I++M
Sbjct: 573 LSLVLMAGTFFFAMMLRKFKNSSYF-----------PGK----LRRVIGDFGVPISILIM 617

Query: 566 VGISCLV-PVKTETLVVPAG--LNPTTVRSWFV-PLNPGLETIXXXXXXXXXXXXXXVYI 621
           V +   +    T+ L VP G  ++ ++ R W + PL    E                V+I
Sbjct: 618 VLVDFFIQDTYTQKLSVPDGFKVSNSSARGWVIHPLGLRSE-FPIWMMFASALPALLVFI 676

Query: 622 IVFMETHIAELIIAKPERRLKKGSGFHMDIVIMSFVNALCGMFGAPWQCVATVRSVSHVS 681
           ++F+E+ I  LI++KPER++ KGSGFH+D++++  +  +  +FG PW    TVRSV+H +
Sbjct: 677 LIFLESQITTLIVSKPERKMVKGSGFHLDLLLVVGMGGVAALFGMPWLSATTVRSVTHAN 736

Query: 682 ALTIMSTTHAPGDKPHIVEVKEQRLTGLLVAVMVGISVLASGWLCLVPMAVLFGVFLYMG 741
           ALT+M     PG    I EVKEQR++GLLVAV+VG+S+L    L  +P+AVLFG+FLYMG
Sbjct: 737 ALTVMGKASTPGAAAQIQEVKEQRISGLLVAVLVGLSILMEPILSRIPLAVLFGIFLYMG 796

Query: 742 ISALGGIQFWDRCILLLKPVKHHPQLPYVRRVPTLKMHMYTLIQVGGVVVLYAVKSSRFS 801
           +++L GIQ +DR +LL KP K+HP +PYV+RV T +MH++T IQ+  + VL+ VKS+  S
Sbjct: 797 VTSLSGIQLFDRILLLFKPPKYHPDVPYVKRVKTWRMHLFTGIQIICLAVLWVVKSTPAS 856

Query: 802 LALPFFLVLMVPLRMSLV-YIFTPLQLRALDG--AQKDIDKDDEPDFYEEAPIP 852
           LALPF L+L VPLR  L+  IF  ++L+ LD   A+   D+++  D Y+E  +P
Sbjct: 857 LALPFVLILTVPLRRVLLPLIFRNVELQCLDADDAKATFDEEEGRDEYDEVAMP 910


>BC096106-1|AAH96106.1|  911|Homo sapiens solute carrier family 4,
           anion exchanger, member 1 (erythrocyte membrane protei
           protein.
          Length = 911

 Score =  530 bits (1307), Expect = e-149
 Identities = 311/774 (40%), Positives = 456/774 (58%), Gaps = 83/774 (10%)

Query: 88  HNDS-ILKRIPDDAEATTVLVGAVGFLDQPTIAFVRLAEGIYMPSITEVPVPVRFMFILL 146
           H+ S IL++IP D+EAT VLVG   FL+QP + FVRL E   + ++ E+PVP+RF+F+LL
Sbjct: 211 HSPSGILEKIPPDSEATLVLVGRADFLEQPVLGFVRLQEAAELEAV-ELPVPIRFLFVLL 269

Query: 147 GPGGADLDYHEVGRSISTLMSNPAFHSIAYKADDRRELLSAINEFLDDSIVLPPGDW-ER 205
           GP    +DY ++GR+ +TLMS   F   AY A  R ELL ++  FLD S+VLPP D    
Sbjct: 270 GPEAPHIDYTQLGRAAATLMSERVFRIDAYMAQSRGELLHSLEGFLDCSLVLPPTDAPSE 329

Query: 206 QALLPLEELRAKSEMIRRRKINALERKRIVADGDKPSDEKKALLAAEAGGMPPEEPDDPL 265
           QALL L  +  + E++RRR           +   KP       L    G      PDDPL
Sbjct: 330 QALLSL--VPVQRELLRRR---------YQSSPAKPDSSFYKGLDLNGG------PDDPL 372

Query: 266 SRTGRLFGGVIRDMKRRYPFYVSDFVDALNGQCVAATIFMYFAAVSSAITFGGLLAEKTY 325
            +TG+LFGG++RD++RRYP+Y+SD  DA + Q +AA IF+YFAA+S AITFGGLL EKT 
Sbjct: 373 QQTGQLFGGLVRDIRRRYPYYLSDITDAFSPQVLAAVIFIYFAALSPAITFGGLLGEKTR 432

Query: 326 GKIGISETLSSGYVRSAVEGDLQVFTSAGGVLFALVAGQPMMITGATGPLLLLDESLANF 385
            ++G+SE L S              T+  G+LFAL+  QP+++ G +GPLL+ +E+  +F
Sbjct: 433 NQMGVSELLIS--------------TAVQGILFALLGAQPLLVVGFSGPLLVFEEAFFSF 478

Query: 386 CHSYGFDFLAARMYCGLWMIVIALCVASVEGSVAVKKITRFTEDXXXXXXXXXXXXEPIT 445
           C + G +++  R++ G W+I++ + V + EGS  V+ I+R+T++            E  +
Sbjct: 479 CETNGLEYIVGRVWIGFWLILLVVLVVAFEGSFLVRFISRYTQEIFSFLISLIFIYETFS 538

Query: 446 STIAVYRANPLGIDYCQFREVALSNSTVQPLLNSTSVGNSSVVAPAPPVSRLPPQPNTAL 505
             I +++ +PL   Y         N  V             ++ P P      P PNTAL
Sbjct: 539 KLIKIFQDHPLQKTY---------NYNV-------------LMVPKPQ----GPLPNTAL 572

Query: 506 FCTMLTLATFVLAYYLRIFRNGKFLGRSSATSRVQVTGRDGIQARRALGDFGVPIAIVLM 565
              +L   TF  A  LR F+N  +             G+     RR +GDFGVPI+I++M
Sbjct: 573 LSLVLMAGTFFFAMMLRKFKNSSYF-----------PGK----LRRVIGDFGVPISILIM 617

Query: 566 VGISCLV-PVKTETLVVPAG--LNPTTVRSWFV-PLNPGLETIXXXXXXXXXXXXXXVYI 621
           V +   +    T+ L VP G  ++ ++ R W + PL    E                V+I
Sbjct: 618 VLVDFFIQDTYTQKLSVPDGFKVSNSSARGWVIHPLGLRSE-FPIWMMFASALPALLVFI 676

Query: 622 IVFMETHIAELIIAKPERRLKKGSGFHMDIVIMSFVNALCGMFGAPWQCVATVRSVSHVS 681
           ++F+E+ I  LI++KPER++ KGSGFH+D++++  +  +  +FG PW    TVRSV+H +
Sbjct: 677 LIFLESQITTLIVSKPERKMVKGSGFHLDLLLVVGMGGVAALFGMPWLSATTVRSVTHAN 736

Query: 682 ALTIMSTTHAPGDKPHIVEVKEQRLTGLLVAVMVGISVLASGWLCLVPMAVLFGVFLYMG 741
           ALT+M     PG    I EVKEQR++GLLVAV+VG+S+L    L  +P+AVLFG+FLYMG
Sbjct: 737 ALTVMGKASTPGAAAQIQEVKEQRISGLLVAVLVGLSILMEPILSRIPLAVLFGIFLYMG 796

Query: 742 ISALGGIQFWDRCILLLKPVKHHPQLPYVRRVPTLKMHMYTLIQVGGVVVLYAVKSSRFS 801
           +++L GIQ +DR +LL KP K+HP +PYV+RV T +MH++T IQ+  + VL+ VKS+  S
Sbjct: 797 VTSLSGIQLFDRILLLFKPPKYHPDVPYVKRVKTWRMHLFTGIQIICLAVLWVVKSTPAS 856

Query: 802 LALPFFLVLMVPLRMSLV-YIFTPLQLRALDG--AQKDIDKDDEPDFYEEAPIP 852
           LALPF L+L VPLR  L+  IF  ++L+ LD   A+   D+++  D Y+E  +P
Sbjct: 857 LALPFVLILTVPLRRVLLPLIFRNVELQCLDADDAKATFDEEEGRDEYDEVAMP 910


>DQ419529-1|ABD74692.1|  911|Homo sapiens solute carrier family 4
           anion exchanger member 1 variant protein.
          Length = 911

 Score =  528 bits (1302), Expect = e-149
 Identities = 310/774 (40%), Positives = 455/774 (58%), Gaps = 83/774 (10%)

Query: 88  HNDS-ILKRIPDDAEATTVLVGAVGFLDQPTIAFVRLAEGIYMPSITEVPVPVRFMFILL 146
           H+ S IL++IP D+EAT VLVG   FL+QP + FVRL E   + ++ E+PVP+RF+F+LL
Sbjct: 211 HSPSGILEKIPPDSEATLVLVGRADFLEQPVLGFVRLQEAAELEAV-ELPVPIRFLFVLL 269

Query: 147 GPGGADLDYHEVGRSISTLMSNPAFHSIAYKADDRRELLSAINEFLDDSIVLPPGDW-ER 205
           GP    +DY ++GR+ +TLMS   F   AY A  R ELL ++  FLD S+VLPP D    
Sbjct: 270 GPEAPHIDYTQLGRAAATLMSERVFRIDAYMAQSRGELLHSLEGFLDCSLVLPPTDAPSE 329

Query: 206 QALLPLEELRAKSEMIRRRKINALERKRIVADGDKPSDEKKALLAAEAGGMPPEEPDDPL 265
           QALL L  +  + E++RRR           +   KP       L    G      PDDPL
Sbjct: 330 QALLSL--VPVQRELLRRR---------YQSSPAKPDSSFYKGLDLNGG------PDDPL 372

Query: 266 SRTGRLFGGVIRDMKRRYPFYVSDFVDALNGQCVAATIFMYFAAVSSAITFGGLLAEKTY 325
            +TG+LFGG++RD++RRYP+Y+SD  DA + Q +AA IF+YFAA+S AITFGGLL EKT 
Sbjct: 373 QQTGQLFGGLVRDIRRRYPYYLSDITDAFSPQVLAAVIFIYFAALSPAITFGGLLGEKTR 432

Query: 326 GKIGISETLSSGYVRSAVEGDLQVFTSAGGVLFALVAGQPMMITGATGPLLLLDESLANF 385
            ++G+SE L S              T+  G+LFAL+  QP+++ G +GPLL+ +E+  +F
Sbjct: 433 NQMGVSELLIS--------------TAVQGILFALLGAQPLLVVGFSGPLLVFEEAFFSF 478

Query: 386 CHSYGFDFLAARMYCGLWMIVIALCVASVEGSVAVKKITRFTEDXXXXXXXXXXXXEPIT 445
           C + G +++  R++ G W+I++ + V + EGS  V+ I+R+T++            E  +
Sbjct: 479 CETNGLEYIVGRVWIGFWLILLVVLVVAFEGSFLVRFISRYTQEIFSFLISLIFIYETFS 538

Query: 446 STIAVYRANPLGIDYCQFREVALSNSTVQPLLNSTSVGNSSVVAPAPPVSRLPPQPNTAL 505
             I +++ +PL   Y         N  V             ++ P P      P PNTAL
Sbjct: 539 KLIKIFQDHPLQKTY---------NYNV-------------LMVPKPQ----GPLPNTAL 572

Query: 506 FCTMLTLATFVLAYYLRIFRNGKFLGRSSATSRVQVTGRDGIQARRALGDFGVPIAIVLM 565
              +L   TF  A  LR F+N  +             G+     RR +GDFGVPI+I++M
Sbjct: 573 LSLVLMAGTFFFAMMLRKFKNSSYF-----------PGK----LRRVIGDFGVPISILIM 617

Query: 566 VGISCLV-PVKTETLVVPAG--LNPTTVRSWFV-PLNPGLETIXXXXXXXXXXXXXXVYI 621
           V +   +    T+ L VP G  ++ ++ R W + PL    E                V+I
Sbjct: 618 VLVDFFIQDTYTQKLSVPDGFKVSNSSARGWVIHPLGLRSE-FPIWMMFASALPALLVFI 676

Query: 622 IVFMETHIAELIIAKPERRLKKGSGFHMDIVIMSFVNALCGMFGAPWQCVATVRSVSHVS 681
           ++F+E+ I  LI++KPER++ KGSGFH+D++++  +  +  +FG PW    TVRSV+H +
Sbjct: 677 LIFLESQITTLIVSKPERKMVKGSGFHLDLLLVVGMGGVAALFGMPWLSATTVRSVTHAN 736

Query: 682 ALTIMSTTHAPGDKPHIVEVKEQRLTGLLVAVMVGISVLASGWLCLVPMAVLFGVFLYMG 741
           ALT+M     PG    I EVKE R++GLLVAV+VG+S+L    L  +P+AVLFG+FLYMG
Sbjct: 737 ALTVMGKASTPGAAAQIQEVKEHRISGLLVAVLVGLSILMEPILSRIPLAVLFGIFLYMG 796

Query: 742 ISALGGIQFWDRCILLLKPVKHHPQLPYVRRVPTLKMHMYTLIQVGGVVVLYAVKSSRFS 801
           +++L GIQ +DR +LL KP K+HP +PYV+RV T +MH++T IQ+  + VL+ VKS+  S
Sbjct: 797 VTSLSGIQLFDRILLLFKPPKYHPDVPYVKRVKTWRMHLFTGIQIICLAVLWVVKSTPAS 856

Query: 802 LALPFFLVLMVPLRMSLV-YIFTPLQLRALDG--AQKDIDKDDEPDFYEEAPIP 852
           LALPF L+L VPLR  L+  IF  ++L+ LD   A+   D+++  D Y+E  +P
Sbjct: 857 LALPFVLILTVPLRRVLLPLIFRNVELQCLDADDAKATFDEEEGRDEYDEVAMP 910


>EF531618-1|ABQ43327.1| 1094|Homo sapiens solute carrier family 4
            sodium bicarbonate cotransporter member 4 variant C
            protein.
          Length = 1094

 Score =  474 bits (1168), Expect = e-133
 Identities = 275/775 (35%), Positives = 425/775 (54%), Gaps = 50/775 (6%)

Query: 90   DSILKRIPDDAEATTVLVGAVGFLDQPTIAFVRLAEGIYMPSITEVPVPVRFMFILLGPG 149
            +  +K++P DAEA+ VLVG V FLD P IAFVRL + + + ++TEVPVP RF+FILLGP 
Sbjct: 272  NKFMKKLPRDAEASNVLVGEVDFLDTPFIAFVRLQQAVMLGALTEVPVPTRFLFILLGPK 331

Query: 150  GADLDYHEVGRSISTLMSNPAFHSIAYKADDRRELLSAINEFLDDSIVLPPGDWERQALL 209
            G    YHE+GR+I+TLMS+  FH IAYKA DR +L++ I+EFLD+ IVLPPG+W+    +
Sbjct: 332  GKAKSYHEIGRAIATLMSDEVFHDIAYKAKDRHDLIAGIDEFLDEVIVLPPGEWD--PAI 389

Query: 210  PLEELRAKSEMIRRRKINALERKRIVADGDKPSDEKKALLAAEAGGMPPEEPDDPLSRTG 269
             +E  ++     +R+ + +   + +  +GD P D          GG       + L RTG
Sbjct: 390  RIEPPKSLPSSDKRKNMYS-GGENVQMNGDTPHD------GGHGGG--GHGDCEELQRTG 440

Query: 270  RLFGGVIRDMKRRYPFYVSDFVDALNGQCVAATIFMYFAAVSSAITFGGLLAEKTYGKIG 329
            R  GG+I+D+KR+ PF+ SDF DALN Q ++A +F+Y A V++AITFGGLL + T    G
Sbjct: 441  RFCGGLIKDIKRKAPFFASDFYDALNIQALSAILFIYLATVTNAITFGGLLGDATDNMQG 500

Query: 330  ISETLSSGYVRSAVEGDLQVFTSAGGVLFALVAGQPMMITGATGPLLLLDESLANFCHSY 389
            + E+               + T+  G +F L AGQP+ I  +TGP+L+ +  L NF    
Sbjct: 501  VLESF--------------LGTAVSGAIFCLFAGQPLTILSSTGPVLVFERLLFNFSKDN 546

Query: 390  GFDFLAARMYCGLWMIVIALCVASVEGSVAVKKITRFTEDXXXXXXXXXXXXEPITSTIA 449
             FD+L  R++ GLW   + L + + + S  V+  TRFTE+            +     I 
Sbjct: 547  NFDYLEFRLWIGLWSAFLCLILVATDASFLVQYFTRFTEEGFSSLISFIFIYDAFKKMIK 606

Query: 450  VYRANPLGIDYCQFREVALSNSTVQPLLNSTSVGNSSVVAP--APPVSRLPPQPNTALFC 507
            +    P+  ++        S + V P   + S+ N + +AP   P +S      NT    
Sbjct: 607  LADYYPINSNFKVGYNTLFSCTCVPPDPANISISNDTTLAPEYLPTMSSTDMYHNTTFDW 666

Query: 508  TMLTL--------------ATFVLAYYLRIFRNGKFLG---RSSATSRVQVTGRDGIQAR 550
              L+                 FV    L  F    FLG    S A  + + +      AR
Sbjct: 667  AFLSKKECSKYGGNLVGNNCNFVPDITLMSFI--LFLGTYTSSMALKKFKTSPYFPTTAR 724

Query: 551  RALGDFGVPIAIVLMVGISCLVPVKTETLVVPAGLNPTTV-RSWFVPLNPGLETIXXXXX 609
            + + DF + ++I++   I  LV V T  L+VP+   PT+  R WFVP  P  E       
Sbjct: 725  KLISDFAIILSILIFCVIDALVGVDTPKLIVPSEFKPTSPNRGWFVP--PFGEN-PWWVC 781

Query: 610  XXXXXXXXXVYIIVFMETHIAELIIAKPERRLKKGSGFHMDIVIMSFVNALCGMFGAPWQ 669
                     V I++FM+  I  +I+ + E +LKKG+G+H+D+  ++ +  +C +   PW 
Sbjct: 782  LAAAIPALLVTILIFMDQQITAVIVNRKEHKLKKGAGYHLDLFWVAILMVICSLMALPWY 841

Query: 670  CVATVRSVSHVSALTIMSTTHAPGDKPHIVEVKEQRLTGLLVAVMVGISVLASGWLCLVP 729
              ATV S++H+ +L + + T APG++P  + V+EQR+TG LV ++ G+SV  +  L  +P
Sbjct: 842  VAATVISIAHIDSLKMETETSAPGEQPKFLGVREQRVTGTLVFILTGLSVFMAPILKFIP 901

Query: 730  MAVLFGVFLYMGISALGGIQFWDRCILLLKPVKHHPQLPYVRRVPTLKMHMYTLIQVGGV 789
            M VL+GVFLYMG+++L G+QF DR  LLL P+KH P   Y+R VP  ++H++T +QV  +
Sbjct: 902  MPVLYGVFLYMGVASLNGVQFMDRLKLLLMPLKHQPDFIYLRHVPLRRVHLFTFLQVLCL 961

Query: 790  VVLYAVKSSRFSLALPFFLVLMVPLRMSLVYIFTPLQLRALDGAQKDIDKDDEPD 844
             +L+ +KS+  ++  P  ++ +V +R  + Y+F+   L  LD    + DK  + D
Sbjct: 962  ALLWILKSTVAAIIFPVMILALVAVRKGMDYLFSQHDLSFLDDVIPEKDKKKKED 1016


>AF310248-1|AAG47773.1| 1079|Homo sapiens sodium bicarbonate
            cotransporter protein.
          Length = 1079

 Score =  474 bits (1168), Expect = e-133
 Identities = 275/775 (35%), Positives = 425/775 (54%), Gaps = 50/775 (6%)

Query: 90   DSILKRIPDDAEATTVLVGAVGFLDQPTIAFVRLAEGIYMPSITEVPVPVRFMFILLGPG 149
            +  +K++P DAEA+ VLVG V FLD P IAFVRL + + + ++TEVPVP RF+FILLGP 
Sbjct: 272  NKFMKKLPRDAEASNVLVGEVDFLDTPFIAFVRLQQAVMLGALTEVPVPTRFLFILLGPK 331

Query: 150  GADLDYHEVGRSISTLMSNPAFHSIAYKADDRRELLSAINEFLDDSIVLPPGDWERQALL 209
            G    YHE+GR+I+TLMS+  FH IAYKA DR +L++ I+EFLD+ IVLPPG+W+    +
Sbjct: 332  GKAKSYHEIGRAIATLMSDEVFHDIAYKAKDRHDLIAGIDEFLDEVIVLPPGEWD--PAI 389

Query: 210  PLEELRAKSEMIRRRKINALERKRIVADGDKPSDEKKALLAAEAGGMPPEEPDDPLSRTG 269
             +E  ++     +R+ + +   + +  +GD P D          GG       + L RTG
Sbjct: 390  RIEPPKSLPSSDKRKNMYS-GGENVQMNGDTPHD------GGHGGG--GHGDCEELQRTG 440

Query: 270  RLFGGVIRDMKRRYPFYVSDFVDALNGQCVAATIFMYFAAVSSAITFGGLLAEKTYGKIG 329
            R  GG+I+D+KR+ PF+ SDF DALN Q ++A +F+Y A V++AITFGGLL + T    G
Sbjct: 441  RFCGGLIKDIKRKAPFFASDFYDALNIQALSAILFIYLATVTNAITFGGLLGDATDNMQG 500

Query: 330  ISETLSSGYVRSAVEGDLQVFTSAGGVLFALVAGQPMMITGATGPLLLLDESLANFCHSY 389
            + E+               + T+  G +F L AGQP+ I  +TGP+L+ +  L NF    
Sbjct: 501  VLESF--------------LGTAVSGAIFCLFAGQPLTILSSTGPVLVFERLLFNFSKDN 546

Query: 390  GFDFLAARMYCGLWMIVIALCVASVEGSVAVKKITRFTEDXXXXXXXXXXXXEPITSTIA 449
             FD+L  R++ GLW   + L + + + S  V+  TRFTE+            +     I 
Sbjct: 547  NFDYLEFRLWIGLWSAFLCLILVATDASFLVQYFTRFTEEGFSSLISFIFIYDAFKKMIK 606

Query: 450  VYRANPLGIDYCQFREVALSNSTVQPLLNSTSVGNSSVVAP--APPVSRLPPQPNTALFC 507
            +    P+  ++        S + V P   + S+ N + +AP   P +S      NT    
Sbjct: 607  LADYYPINSNFKVGYNTLFSCTCVPPDPANISISNDTTLAPEYLPTMSSTDMYHNTTFDW 666

Query: 508  TMLTL--------------ATFVLAYYLRIFRNGKFLG---RSSATSRVQVTGRDGIQAR 550
              L+                 FV    L  F    FLG    S A  + + +      AR
Sbjct: 667  AFLSKKECSKYGGNLVGNNCNFVPDITLMSFI--LFLGTYTSSMALKKFKTSPYFPTTAR 724

Query: 551  RALGDFGVPIAIVLMVGISCLVPVKTETLVVPAGLNPTTV-RSWFVPLNPGLETIXXXXX 609
            + + DF + ++I++   I  LV V T  L+VP+   PT+  R WFVP  P  E       
Sbjct: 725  KLISDFAIILSILIFCVIDALVGVDTPKLIVPSEFKPTSPNRGWFVP--PFGEN-PWWVC 781

Query: 610  XXXXXXXXXVYIIVFMETHIAELIIAKPERRLKKGSGFHMDIVIMSFVNALCGMFGAPWQ 669
                     V I++FM+  I  +I+ + E +LKKG+G+H+D+  ++ +  +C +   PW 
Sbjct: 782  LAAAIPALLVTILIFMDRQITAVIVNRKEHKLKKGAGYHLDLFWVAILMVICSLMALPWY 841

Query: 670  CVATVRSVSHVSALTIMSTTHAPGDKPHIVEVKEQRLTGLLVAVMVGISVLASGWLCLVP 729
              ATV S++H+ +L + + T APG++P  + V+EQR+TG LV ++ G+SV  +  L  +P
Sbjct: 842  VAATVISIAHIDSLRMETETSAPGEQPKFLGVREQRVTGTLVFILTGLSVFMAPILKFIP 901

Query: 730  MAVLFGVFLYMGISALGGIQFWDRCILLLKPVKHHPQLPYVRRVPTLKMHMYTLIQVGGV 789
            M VL+GVFLYMG+++L G+QF DR  LLL P+KH P   Y+R VP  ++H++T +QV  +
Sbjct: 902  MPVLYGVFLYMGVASLNGVQFMDRLKLLLMPLKHQPDFIYLRHVPLRRVHLFTFLQVLCL 961

Query: 790  VVLYAVKSSRFSLALPFFLVLMVPLRMSLVYIFTPLQLRALDGAQKDIDKDDEPD 844
             +L+ +KS+  ++  P  ++ +V +R  + Y+F+   L  LD    + DK  + D
Sbjct: 962  ALLWILKSTVAAIIFPVMILALVAVRKGMDYLFSQHDLSFLDDVIPEKDKKKKED 1016


>AF069510-1|AAD42020.1| 1079|Homo sapiens sodium bicarbonate
            cotransporter protein.
          Length = 1079

 Score =  474 bits (1168), Expect = e-133
 Identities = 275/775 (35%), Positives = 425/775 (54%), Gaps = 50/775 (6%)

Query: 90   DSILKRIPDDAEATTVLVGAVGFLDQPTIAFVRLAEGIYMPSITEVPVPVRFMFILLGPG 149
            +  +K++P DAEA+ VLVG V FLD P IAFVRL + + + ++TEVPVP RF+FILLGP 
Sbjct: 272  NKFMKKLPRDAEASNVLVGEVDFLDTPFIAFVRLQQAVMLGALTEVPVPTRFLFILLGPK 331

Query: 150  GADLDYHEVGRSISTLMSNPAFHSIAYKADDRRELLSAINEFLDDSIVLPPGDWERQALL 209
            G    YHE+GR+I+TLMS+  FH IAYKA DR +L++ I+EFLD+ IVLPPG+W+    +
Sbjct: 332  GKAKSYHEIGRAIATLMSDEVFHDIAYKAKDRHDLIAGIDEFLDEVIVLPPGEWD--PAI 389

Query: 210  PLEELRAKSEMIRRRKINALERKRIVADGDKPSDEKKALLAAEAGGMPPEEPDDPLSRTG 269
             +E  ++     +R+ + +   + +  +GD P D          GG       + L RTG
Sbjct: 390  RIEPPKSLPSSDKRKNMYS-GGENVQMNGDTPHD------GGHGGG--GHGDCEELQRTG 440

Query: 270  RLFGGVIRDMKRRYPFYVSDFVDALNGQCVAATIFMYFAAVSSAITFGGLLAEKTYGKIG 329
            R  GG+I+D+KR+ PF+ SDF DALN Q ++A +F+Y A V++AITFGGLL + T    G
Sbjct: 441  RFCGGLIKDIKRKAPFFASDFYDALNIQALSAILFIYLATVTNAITFGGLLGDATDNMQG 500

Query: 330  ISETLSSGYVRSAVEGDLQVFTSAGGVLFALVAGQPMMITGATGPLLLLDESLANFCHSY 389
            + E+               + T+  G +F L AGQP+ I  +TGP+L+ +  L NF    
Sbjct: 501  VLESF--------------LGTAVSGAIFCLFAGQPLTILSSTGPVLVFERLLFNFSKDN 546

Query: 390  GFDFLAARMYCGLWMIVIALCVASVEGSVAVKKITRFTEDXXXXXXXXXXXXEPITSTIA 449
             FD+L  R++ GLW   + L + + + S  V+  TRFTE+            +     I 
Sbjct: 547  NFDYLEFRLWIGLWSAFLCLILVATDASFLVQYFTRFTEEGFSSLISFIFIYDAFKKMIK 606

Query: 450  VYRANPLGIDYCQFREVALSNSTVQPLLNSTSVGNSSVVAP--APPVSRLPPQPNTALFC 507
            +    P+  ++        S + V P   + S+ N + +AP   P +S      NT    
Sbjct: 607  LADYYPINSNFKVGYNTLFSCTCVPPDPANISISNDTTLAPEYLPTMSSTDMYHNTTFDW 666

Query: 508  TMLTL--------------ATFVLAYYLRIFRNGKFLG---RSSATSRVQVTGRDGIQAR 550
              L+                 FV    L  F    FLG    S A  + + +      AR
Sbjct: 667  AFLSKKECSKYGGNLVGNNCNFVPDITLMSFI--LFLGTYTSSMALKKFKTSPYFPTTAR 724

Query: 551  RALGDFGVPIAIVLMVGISCLVPVKTETLVVPAGLNPTTV-RSWFVPLNPGLETIXXXXX 609
            + + DF + ++I++   I  LV V T  L+VP+   PT+  R WFVP  P  E       
Sbjct: 725  KLISDFAIILSILIFCVIDALVGVDTPKLIVPSEFKPTSPNRGWFVP--PFGEN-PWWVC 781

Query: 610  XXXXXXXXXVYIIVFMETHIAELIIAKPERRLKKGSGFHMDIVIMSFVNALCGMFGAPWQ 669
                     V I++FM+  I  +I+ + E +LKKG+G+H+D+  ++ +  +C +   PW 
Sbjct: 782  LAAAIPALLVTILIFMDQQITAVIVNRKEHKLKKGAGYHLDLFWVAILMVICSLMALPWY 841

Query: 670  CVATVRSVSHVSALTIMSTTHAPGDKPHIVEVKEQRLTGLLVAVMVGISVLASGWLCLVP 729
              ATV S++H+ +L + + T APG++P  + V+EQR+TG LV ++ G+SV  +  L  +P
Sbjct: 842  VAATVISIAHIDSLKMETETSAPGEQPKFLGVREQRVTGTLVFILTGLSVFMAPILKFIP 901

Query: 730  MAVLFGVFLYMGISALGGIQFWDRCILLLKPVKHHPQLPYVRRVPTLKMHMYTLIQVGGV 789
            M VL+GVFLYMG+++L G+QF DR  LLL P+KH P   Y+R VP  ++H++T +QV  +
Sbjct: 902  MPVLYGVFLYMGVASLNGVQFMDRLKLLLMPLKHQPDFIYLRHVPLRRVHLFTFLQVLCL 961

Query: 790  VVLYAVKSSRFSLALPFFLVLMVPLRMSLVYIFTPLQLRALDGAQKDIDKDDEPD 844
             +L+ +KS+  ++  P  ++ +V +R  + Y+F+   L  LD    + DK  + D
Sbjct: 962  ALLWILKSTVAAIIFPVMILALVAVRKGMDYLFSQHDLSFLDDVIPEKDKKKKED 1016


>AF011390-1|AAC39840.1| 1079|Homo sapiens pancreas sodium bicarbonate
            cotransporter protein.
          Length = 1079

 Score =  474 bits (1168), Expect = e-133
 Identities = 275/775 (35%), Positives = 425/775 (54%), Gaps = 50/775 (6%)

Query: 90   DSILKRIPDDAEATTVLVGAVGFLDQPTIAFVRLAEGIYMPSITEVPVPVRFMFILLGPG 149
            +  +K++P DAEA+ VLVG V FLD P IAFVRL + + + ++TEVPVP RF+FILLGP 
Sbjct: 272  NKFMKKLPRDAEASNVLVGEVDFLDTPFIAFVRLQQAVMLGALTEVPVPTRFLFILLGPK 331

Query: 150  GADLDYHEVGRSISTLMSNPAFHSIAYKADDRRELLSAINEFLDDSIVLPPGDWERQALL 209
            G    YHE+GR+I+TLMS+  FH IAYKA DR +L++ I+EFLD+ IVLPPG+W+    +
Sbjct: 332  GKAKSYHEIGRAIATLMSDEVFHDIAYKAKDRHDLIAGIDEFLDEVIVLPPGEWD--PAI 389

Query: 210  PLEELRAKSEMIRRRKINALERKRIVADGDKPSDEKKALLAAEAGGMPPEEPDDPLSRTG 269
             +E  ++     +R+ + +   + +  +GD P D          GG       + L RTG
Sbjct: 390  RIEPPKSLPSSDKRKNMYS-GGENVQMNGDTPHD------GGHGGG--GHGDCEELQRTG 440

Query: 270  RLFGGVIRDMKRRYPFYVSDFVDALNGQCVAATIFMYFAAVSSAITFGGLLAEKTYGKIG 329
            R  GG+I+D+KR+ PF+ SDF DALN Q ++A +F+Y A V++AITFGGLL + T    G
Sbjct: 441  RFCGGLIKDIKRKAPFFASDFYDALNIQALSAILFIYLATVTNAITFGGLLGDATDNMQG 500

Query: 330  ISETLSSGYVRSAVEGDLQVFTSAGGVLFALVAGQPMMITGATGPLLLLDESLANFCHSY 389
            + E+               + T+  G +F L AGQP+ I  +TGP+L+ +  L NF    
Sbjct: 501  VLESF--------------LGTAVSGAIFCLFAGQPLTILSSTGPVLVFERLLFNFSKDN 546

Query: 390  GFDFLAARMYCGLWMIVIALCVASVEGSVAVKKITRFTEDXXXXXXXXXXXXEPITSTIA 449
             FD+L  R++ GLW   + L + + + S  V+  TRFTE+            +     I 
Sbjct: 547  NFDYLEFRLWIGLWSAFLCLILVATDASFLVQYFTRFTEEGFSSLISFIFIYDAFKKMIK 606

Query: 450  VYRANPLGIDYCQFREVALSNSTVQPLLNSTSVGNSSVVAP--APPVSRLPPQPNTALFC 507
            +    P+  ++        S + V P   + S+ N + +AP   P +S      NT    
Sbjct: 607  LADYYPINSNFKVGYNTLFSCTCVPPDPANISISNDTTLAPEYLPTMSSTDMYHNTTFDW 666

Query: 508  TMLTL--------------ATFVLAYYLRIFRNGKFLG---RSSATSRVQVTGRDGIQAR 550
              L+                 FV    L  F    FLG    S A  + + +      AR
Sbjct: 667  AFLSKKECSKYGGNLVGNNCNFVPDITLMSFI--LFLGTYTSSMALKKFKTSPYFPTTAR 724

Query: 551  RALGDFGVPIAIVLMVGISCLVPVKTETLVVPAGLNPTTV-RSWFVPLNPGLETIXXXXX 609
            + + DF + ++I++   I  LV V T  L+VP+   PT+  R WFVP  P  E       
Sbjct: 725  KLISDFAIILSILIFCVIDALVGVDTPKLIVPSEFKPTSPNRGWFVP--PFGEN-PWWVC 781

Query: 610  XXXXXXXXXVYIIVFMETHIAELIIAKPERRLKKGSGFHMDIVIMSFVNALCGMFGAPWQ 669
                     V I++FM+  I  +I+ + E +LKKG+G+H+D+  ++ +  +C +   PW 
Sbjct: 782  LAAAIPALLVTILIFMDQQITAVIVNRKEHKLKKGAGYHLDLFWVAILMVICSLMALPWY 841

Query: 670  CVATVRSVSHVSALTIMSTTHAPGDKPHIVEVKEQRLTGLLVAVMVGISVLASGWLCLVP 729
              ATV S++H+ +L + + T APG++P  + V+EQR+TG LV ++ G+SV  +  L  +P
Sbjct: 842  VAATVISIAHIDSLKMETETSAPGEQPKFLGVREQRVTGTLVFILTGLSVFMAPILKFIP 901

Query: 730  MAVLFGVFLYMGISALGGIQFWDRCILLLKPVKHHPQLPYVRRVPTLKMHMYTLIQVGGV 789
            M VL+GVFLYMG+++L G+QF DR  LLL P+KH P   Y+R VP  ++H++T +QV  +
Sbjct: 902  MPVLYGVFLYMGVASLNGVQFMDRLKLLLMPLKHQPDFIYLRHVPLRRVHLFTFLQVLCL 961

Query: 790  VVLYAVKSSRFSLALPFFLVLMVPLRMSLVYIFTPLQLRALDGAQKDIDKDDEPD 844
             +L+ +KS+  ++  P  ++ +V +R  + Y+F+   L  LD    + DK  + D
Sbjct: 962  ALLWILKSTVAAIIFPVMILALVAVRKGMDYLFSQHDLSFLDDVIPEKDKKKKED 1016


>AF007216-1|AAC51645.1| 1035|Homo sapiens sodium bicarbonate
           cotransporter protein.
          Length = 1035

 Score =  474 bits (1168), Expect = e-133
 Identities = 275/775 (35%), Positives = 425/775 (54%), Gaps = 50/775 (6%)

Query: 90  DSILKRIPDDAEATTVLVGAVGFLDQPTIAFVRLAEGIYMPSITEVPVPVRFMFILLGPG 149
           +  +K++P DAEA+ VLVG V FLD P IAFVRL + + + ++TEVPVP RF+FILLGP 
Sbjct: 228 NKFMKKLPRDAEASNVLVGEVDFLDTPFIAFVRLQQAVMLGALTEVPVPTRFLFILLGPK 287

Query: 150 GADLDYHEVGRSISTLMSNPAFHSIAYKADDRRELLSAINEFLDDSIVLPPGDWERQALL 209
           G    YHE+GR+I+TLMS+  FH IAYKA DR +L++ I+EFLD+ IVLPPG+W+    +
Sbjct: 288 GKAKSYHEIGRAIATLMSDEVFHDIAYKAKDRHDLIAGIDEFLDEVIVLPPGEWD--PAI 345

Query: 210 PLEELRAKSEMIRRRKINALERKRIVADGDKPSDEKKALLAAEAGGMPPEEPDDPLSRTG 269
            +E  ++     +R+ + +   + +  +GD P D          GG       + L RTG
Sbjct: 346 RIEPPKSLPSSDKRKNMYS-GGENVQMNGDTPHD------GGHGGG--GHGDCEELQRTG 396

Query: 270 RLFGGVIRDMKRRYPFYVSDFVDALNGQCVAATIFMYFAAVSSAITFGGLLAEKTYGKIG 329
           R  GG+I+D+KR+ PF+ SDF DALN Q ++A +F+Y A V++AITFGGLL + T    G
Sbjct: 397 RFCGGLIKDIKRKAPFFASDFYDALNIQALSAILFIYLATVTNAITFGGLLGDATDNMQG 456

Query: 330 ISETLSSGYVRSAVEGDLQVFTSAGGVLFALVAGQPMMITGATGPLLLLDESLANFCHSY 389
           + E+               + T+  G +F L AGQP+ I  +TGP+L+ +  L NF    
Sbjct: 457 VLESF--------------LGTAVSGAIFCLFAGQPLTILSSTGPVLVFERLLFNFSKDN 502

Query: 390 GFDFLAARMYCGLWMIVIALCVASVEGSVAVKKITRFTEDXXXXXXXXXXXXEPITSTIA 449
            FD+L  R++ GLW   + L + + + S  V+  TRFTE+            +     I 
Sbjct: 503 NFDYLEFRLWIGLWSAFLCLILVATDASFLVQYFTRFTEEGFSSLISFIFIYDAFKKMIK 562

Query: 450 VYRANPLGIDYCQFREVALSNSTVQPLLNSTSVGNSSVVAP--APPVSRLPPQPNTALFC 507
           +    P+  ++        S + V P   + S+ N + +AP   P +S      NT    
Sbjct: 563 LADYYPINSNFKVGYNTLFSCTCVPPDPANISISNDTTLAPEYLPTMSSTDMYHNTTFDW 622

Query: 508 TMLTL--------------ATFVLAYYLRIFRNGKFLG---RSSATSRVQVTGRDGIQAR 550
             L+                 FV    L  F    FLG    S A  + + +      AR
Sbjct: 623 AFLSKKECSKYGGNLVGNNCNFVPDITLMSFI--LFLGTYTSSMALKKFKTSPYFPTTAR 680

Query: 551 RALGDFGVPIAIVLMVGISCLVPVKTETLVVPAGLNPTTV-RSWFVPLNPGLETIXXXXX 609
           + + DF + ++I++   I  LV V T  L+VP+   PT+  R WFVP  P  E       
Sbjct: 681 KLISDFAIILSILIFCVIDALVGVDTPKLIVPSEFKPTSPNRGWFVP--PFGEN-PWWVC 737

Query: 610 XXXXXXXXXVYIIVFMETHIAELIIAKPERRLKKGSGFHMDIVIMSFVNALCGMFGAPWQ 669
                    V I++FM+  I  +I+ + E +LKKG+G+H+D+  ++ +  +C +   PW 
Sbjct: 738 LAAAIPALLVTILIFMDQQITAVIVNRKEHKLKKGAGYHLDLFWVAILMVICSLMALPWY 797

Query: 670 CVATVRSVSHVSALTIMSTTHAPGDKPHIVEVKEQRLTGLLVAVMVGISVLASGWLCLVP 729
             ATV S++H+ +L + + T APG++P  + V+EQR+TG LV ++ G+SV  +  L  +P
Sbjct: 798 VAATVISIAHIDSLKMETETSAPGEQPKFLGVREQRVTGTLVFILTGLSVFMAPILKFIP 857

Query: 730 MAVLFGVFLYMGISALGGIQFWDRCILLLKPVKHHPQLPYVRRVPTLKMHMYTLIQVGGV 789
           M VL+GVFLYMG+++L G+QF DR  LLL P+KH P   Y+R VP  ++H++T +QV  +
Sbjct: 858 MPVLYGVFLYMGVASLNGVQFMDRLKLLLMPLKHQPDFIYLRHVPLRRVHLFTFLQVLCL 917

Query: 790 VVLYAVKSSRFSLALPFFLVLMVPLRMSLVYIFTPLQLRALDGAQKDIDKDDEPD 844
            +L+ +KS+  ++  P  ++ +V +R  + Y+F+   L  LD    + DK  + D
Sbjct: 918 ALLWILKSTVAAIIFPVMILALVAVRKGMDYLFSQHDLSFLDDVIPEKDKKKKED 972


>AF053754-1|AAF21719.1| 1079|Homo sapiens electrogenic Na+ bicarbonate
            cotransporter form 2 protein.
          Length = 1079

 Score =  473 bits (1165), Expect = e-132
 Identities = 275/775 (35%), Positives = 425/775 (54%), Gaps = 50/775 (6%)

Query: 90   DSILKRIPDDAEATTVLVGAVGFLDQPTIAFVRLAEGIYMPSITEVPVPVRFMFILLGPG 149
            +  +K++P DAEA+ VLVG V FLD P IAFVRL + + + ++TEVPVP RF+FILLGP 
Sbjct: 272  NKFMKKLPRDAEASNVLVGEVDFLDTPFIAFVRLQQAVMLGALTEVPVPTRFLFILLGPK 331

Query: 150  GADLDYHEVGRSISTLMSNPAFHSIAYKADDRRELLSAINEFLDDSIVLPPGDWERQALL 209
            G    YHE+GR+I+TLMS+  FH IAYKA DRR+L++ I+EFLD+ IVLPPG+W+    +
Sbjct: 332  GKAKSYHEIGRAIATLMSDEVFHDIAYKAKDRRDLIAGIDEFLDEVIVLPPGEWD--PAI 389

Query: 210  PLEELRAKSEMIRRRKINALERKRIVADGDKPSDEKKALLAAEAGGMPPEEPDDPLSRTG 269
             +E  ++     +R+ + +   + +  +GD P D          GG       + L RTG
Sbjct: 390  RIEPPKSLPSSDKRKNMYS-GGENVQMNGDTPHD------GGHGGG--GHGDCEELQRTG 440

Query: 270  RLFGGVIRDMKRRYPFYVSDFVDALNGQCVAATIFMYFAAVSSAITFGGLLAEKTYGKIG 329
            R  GG+I+D+KR+ PF+ SDF DALN Q ++A +F+Y A V++AITFGGLL + T    G
Sbjct: 441  RFCGGLIKDIKRKAPFFASDFYDALNIQALSAILFIYLATVTNAITFGGLLGDATDNMQG 500

Query: 330  ISETLSSGYVRSAVEGDLQVFTSAGGVLFALVAGQPMMITGATGPLLLLDESLANFCHSY 389
            + E+               + T+  G +F L AGQP+ I  +TGP+L+ +  L NF    
Sbjct: 501  VLESF--------------LGTAVSGAIFCLFAGQPLTILSSTGPVLVFERLLFNFSKDN 546

Query: 390  GFDFLAARMYCGLWMIVIALCVASVEGSVAVKKITRFTEDXXXXXXXXXXXXEPITSTIA 449
             FD+L  R++ GLW   + L + + + S  V+  TRFTE+            +     I 
Sbjct: 547  NFDYLEFRLWIGLWSAFLCLILVATDASFLVQYFTRFTEEGFSSLISFIFIYDAFKKMIK 606

Query: 450  VYRANPLGIDYCQFREVALSNSTVQPLLNSTSVGNSSVVAP--APPVSRLPPQPNTALFC 507
            +    P+  ++        S + V P   + S+ N + +AP   P +S      NT    
Sbjct: 607  LADYYPINSNFKVGYNTLFSCTCVPPDPANISISNDTTLAPEYLPTMSSTDMYHNTTFDW 666

Query: 508  TMLTL--------------ATFVLAYYLRIFRNGKFLG---RSSATSRVQVTGRDGIQAR 550
              L+                 FV    L  F    FLG    S A  + + +      AR
Sbjct: 667  AFLSKKECSKYGGNLVGNNCNFVPDITLMSFI--LFLGTYTSSMALKKFKTSPYFPTTAR 724

Query: 551  RALGDFGVPIAIVLMVGISCLVPVKTETLVVPAGLNPTTV-RSWFVPLNPGLETIXXXXX 609
            + + DF + ++I++   I  LV V T  L+VP+   PT+  R WFVP  P  E       
Sbjct: 725  KLISDFAIILSILIFCVIDALVGVGTPKLIVPSEFKPTSPNRGWFVP--PFGEN-PWWVC 781

Query: 610  XXXXXXXXXVYIIVFMETHIAELIIAKPERRLKKGSGFHMDIVIMSFVNALCGMFGAPWQ 669
                     V I++FM+  I  +I+ + E +LKKG+G+H+D+  ++ +  +C +   PW 
Sbjct: 782  LAAAIPALLVTILIFMDQQITAVIVNRKEHKLKKGAGYHLDLFWVAILMVICSLMALPWY 841

Query: 670  CVATVRSVSHVSALTIMSTTHAPGDKPHIVEVKEQRLTGLLVAVMVGISVLASGWLCLVP 729
              ATV S++H+ +L + + T APG++P  + V+EQR+TG LV ++ G+SV  +  L  +P
Sbjct: 842  VAATVISIAHIDSLKMETETSAPGEQPKFLGVREQRVTGTLVFILTGLSVFMAPILKFIP 901

Query: 730  MAVLFGVFLYMGISALGGIQFWDRCILLLKPVKHHPQLPYVRRVPTLKMHMYTLIQVGGV 789
            M VL+GVFLYM +++L G+QF DR  LLL P+KH P   Y+R VP  ++H++T +QV  +
Sbjct: 902  MPVLYGVFLYMRVASLNGVQFMDRLKLLLMPLKHQPDFIYLRHVPLRRVHLFTFLQVLCL 961

Query: 790  VVLYAVKSSRFSLALPFFLVLMVPLRMSLVYIFTPLQLRALDGAQKDIDKDDEPD 844
             +L+ +KS+  ++  P  ++ +V +R  + Y+F+   L  LD    + DK  + D
Sbjct: 962  ALLWILKSTVAAIIFPVMILALVAVRKGMDYLFSQHDLSFLDDVISEKDKKKKED 1016


>AF053753-1|AAF21718.1| 1079|Homo sapiens electrogenic Na+ bicarbonate
            cotransporter protein.
          Length = 1079

 Score =  469 bits (1157), Expect = e-131
 Identities = 272/775 (35%), Positives = 423/775 (54%), Gaps = 50/775 (6%)

Query: 90   DSILKRIPDDAEATTVLVGAVGFLDQPTIAFVRLAEGIYMPSITEVPVPVRFMFILLGPG 149
            +  +K++P DAEA+ VLVG V FLD P IAFVRL + + + ++TEVPVP RF+FILLGP 
Sbjct: 272  NKFMKKLPRDAEASNVLVGEVDFLDTPFIAFVRLQQAVMLGALTEVPVPTRFLFILLGPK 331

Query: 150  GADLDYHEVGRSISTLMSNPAFHSIAYKADDRRELLSAINEFLDDSIVLPPGDWERQALL 209
            G    YHE+GR+I+TLMS+  FH IAYKA DR +L++ I+EFLD+ IVLPPG+W+    +
Sbjct: 332  GKAKSYHEIGRAIATLMSDEVFHDIAYKAKDRHDLIAGIDEFLDEVIVLPPGEWD--PAI 389

Query: 210  PLEELRAKSEMIRRRKINALERKRIVADGDKPSDEKKALLAAEAGGMPPEEPDDPLSRTG 269
             +E  ++     +R+ + +   + +  +GD P D          GG       + L RTG
Sbjct: 390  RIEPPKSLPSSDKRKNMYS-GGENVQMNGDTPHD------GGHGGG--GHGDCEELQRTG 440

Query: 270  RLFGGVIRDMKRRYPFYVSDFVDALNGQCVAATIFMYFAAVSSAITFGGLLAEKTYGKIG 329
            R  GG+I+D+KR+ PF+ SDF DALN Q ++A +F+Y A V++AITFGGLL + T    G
Sbjct: 441  RFCGGLIKDIKRKAPFFASDFYDALNIQALSAILFIYLATVTNAITFGGLLGDATDNMQG 500

Query: 330  ISETLSSGYVRSAVEGDLQVFTSAGGVLFALVAGQPMMITGATGPLLLLDESLANFCHSY 389
            + E+               + T+  G +F L AGQP+ I  +TGP+L+ +  L NF    
Sbjct: 501  VLESF--------------LGTAVSGAIFCLFAGQPLTILSSTGPVLVFERLLFNFSKDN 546

Query: 390  GFDFLAARMYCGLWMIVIALCVASVEGSVAVKKITRFTEDXXXXXXXXXXXXEPITSTIA 449
             FD+L  R++ GLW   + L + + + S  V+  TRFTE+            +     + 
Sbjct: 547  NFDYLEFRLWIGLWSAFLCLILVATDASFLVQYFTRFTEEGFSSLISFIFIYDAFKKMVK 606

Query: 450  VYRANPLGIDYCQFREVALSNSTVQPLLNSTSVGNSSVVAP--APPVSRLPPQPNTALFC 507
            +    P+  ++        S + V P   + S+ N + +AP   P +       NT    
Sbjct: 607  LADYYPINSNFKVGYNTLFSCTCVPPDPANISISNDTTLAPEYLPTMPSTDMYHNTTFDW 666

Query: 508  TMLTL--------------ATFVLAYYLRIFRNGKFLG---RSSATSRVQVTGRDGIQAR 550
              L+                 FV    L  F    FLG    S A  + + +      AR
Sbjct: 667  AFLSKKECSKYGGNLVGNNCNFVPDITLMSFI--LFLGTYTSSMALKKFKTSPYFPTTAR 724

Query: 551  RALGDFGVPIAIVLMVGISCLVPVKTETLVVPAGLNPTTV-RSWFVPLNPGLETIXXXXX 609
            + + DF + ++I++   I  LV V T  L+VP+   PT+  R WFVP  P  E       
Sbjct: 725  KLISDFAIILSILIFCVIDALVGVDTPKLIVPSEFKPTSPNRGWFVP--PFGEN-PWWVC 781

Query: 610  XXXXXXXXXVYIIVFMETHIAELIIAKPERRLKKGSGFHMDIVIMSFVNALCGMFGAPWQ 669
                     V I++FM+  I  +I+ + E +LKKG+G+H+D+  ++ +  +C +   PW 
Sbjct: 782  LAAAIPALLVTILIFMDQQITAVIVNRKEHKLKKGAGYHLDLFWVAILMVICSLMALPWY 841

Query: 670  CVATVRSVSHVSALTIMSTTHAPGDKPHIVEVKEQRLTGLLVAVMVGISVLASGWLCLVP 729
              ATV S++H+ +L + + T APG++P  + V+EQR+TG LV ++ G+SV  +  L  +P
Sbjct: 842  VAATVISIAHIDSLKMETETSAPGEQPKFLGVREQRVTGTLVFILTGLSVFMAPILKFIP 901

Query: 730  MAVLFGVFLYMGISALGGIQFWDRCILLLKPVKHHPQLPYVRRVPTLKMHMYTLIQVGGV 789
            M VL+GVFLY G+++L G+QF DR  LLL P+KH P   Y+R VP  ++H++T +QV  +
Sbjct: 902  MPVLYGVFLYRGVASLNGVQFMDRLKLLLMPLKHQPDFVYLRHVPLRRVHLFTFLQVLCL 961

Query: 790  VVLYAVKSSRFSLALPFFLVLMVPLRMSLVYIFTPLQLRALDGAQKDIDKDDEPD 844
             +L+ +KS+  ++  P  ++ +V +R  + Y+F+   L  LD    + DK  + D
Sbjct: 962  ALLWILKSTVAAIIFPVMILALVAVRKGMDYLFSQHDLSFLDDVIPEKDKKKKED 1016


>AF293337-1|AAK97072.1| 1121|Homo sapiens sodium bicarbonate
            cotransporter NBC4c protein.
          Length = 1121

 Score =  430 bits (1059), Expect = e-119
 Identities = 268/816 (32%), Positives = 431/816 (52%), Gaps = 69/816 (8%)

Query: 74   LAHA-SESQDELRRTHN-----DSILKRIPDDAEATTVLVGAVGFLDQPTIAFVRLAEGI 127
            L HA S S +++  T N     +  +K+IP D+EA+ VLVG V FLDQP IAFVRL +  
Sbjct: 270  LCHAQSRSMNDISLTPNTDQRKNKFMKKIPKDSEASNVLVGEVDFLDQPFIAFVRLIQSA 329

Query: 128  YMPSITEVPVPVRFMFILLGPGGADLDYHEVGRSISTLMSNPAFHSIAYKADDRRELLSA 187
             +  +TEVPVP RF+FILLGP G    Y+E+GR+I+TLM +  F  +AYKA +R +L++ 
Sbjct: 330  MLGGVTEVPVPTRFLFILLGPSGRAKSYNEIGRAIATLMVDDLFSDVAYKARNREDLIAG 389

Query: 188  INEFLDDSIVLPPGDWERQALLPLEELRAKSEMIRRRKINALE-----RKRIVADGDKPS 242
            I+EFLD+ IVLPPG+W+    + +E  +      +R+ + +L         +   G  P 
Sbjct: 390  IDEFLDEVIVLPPGEWDPN--IRIEPPKKVPSADKRKSVFSLAELGQMNGSVGGGGGAPG 447

Query: 243  DEKKALLAAEAGG-----------------MPP-EEPDDPLSRTGRLFGGVIRDMKRRYP 284
                      +GG                 MP   E  + L  TGR FGG+  D+KR+ P
Sbjct: 448  GGNGGGGGGGSGGGAGSGGAGGTSSGDDGEMPAMHEIGEELIWTGRFFGGLCLDIKRKLP 507

Query: 285  FYVSDFVDALNGQCVAATIFMYFAAVSSAITFGGLLAEKTYGKIGISETLSSGYVRSAVE 344
            ++ SDF D  + Q ++A +F+Y   +++AITFGGLL + T    G+ E+           
Sbjct: 508  WFPSDFYDGFHIQSISAILFIYLGCITNAITFGGLLGDATDNYQGVMESF---------- 557

Query: 345  GDLQVFTSAGGVLFALVAGQPMMITGATGPLLLLDESLANFCHSYGFDFLAARMYCGLWM 404
                + T+  G LF L +GQP++I  +TGP+L+ ++ L +F    G D++  R++ GL  
Sbjct: 558  ----LGTAMAGSLFCLFSGQPLIILSSTGPILIFEKLLFDFSKGNGLDYMEFRLWIGLHS 613

Query: 405  IVIALCVASVEGSVAVKKITRFTEDXXXXXXXXXXXXEPITSTIAVYRANPLGIDYCQFR 464
             V  L + + + S  +K ITRFTE+            + I   I  ++  P+ +D+    
Sbjct: 614  AVQCLILVATDASFIIKYITRFTEEGFSTLISFIFIYDAIKKMIGAFKYYPINMDFKPNF 673

Query: 465  EVALSNSTVQPLLNSTSVGNSSV-VAPAPPVSRLPPQPNTALFCTMLTLATFVLAYYLRI 523
                    V P   +T+V N+S  +AP    S       TAL  ++L+     L+Y  R+
Sbjct: 674  ITTYKCECVAPDTVNTTVFNASAPLAPDTNASLYNLLNLTALDWSLLSKKE-CLSYGGRL 732

Query: 524  FRNG-KFLGRSSATSRVQVTGRDGI---------------QARRALGDFGVPIAIVLMVG 567
              N  KF+   +  S +   G   +               + R  + DF +  +I++  G
Sbjct: 733  LGNSCKFIPDLALMSFILFFGTYSMTLTLKKFKFSRYFPTKVRALVADFSIVFSILMFCG 792

Query: 568  ISCLVPVKTETLVVPAGLNPTTV-RSWFV-PLNPGLETIXXXXXXXXXXXXXXVYIIVFM 625
            I     ++T  L VP+ + PT   R WFV P       +              V I++FM
Sbjct: 793  IDACFGLETPKLHVPSVIKPTRPDRGWFVAPFGKNPWWV----YPASILPALLVTILIFM 848

Query: 626  ETHIAELIIAKPERRLKKGSGFHMDIVIMSFVNALCGMFGAPWQCVATVRSVSHVSALTI 685
            +  I  +I+ + E +LKK +G+H+D+  +  + ALC   G PW   ATV S++H+ +L +
Sbjct: 849  DQQITAVIVNRKENKLKKAAGYHLDLFWVGILMALCSFMGLPWYVAATVISIAHIDSLKM 908

Query: 686  MSTTHAPGDKPHIVEVKEQRLTGLLVAVMVGISVLASGWLCLVPMAVLFGVFLYMGISAL 745
             + T APG++P  + V+EQR+TG++V ++ GISV  +  L  +P+ VL+GVFLYMG+++L
Sbjct: 909  ETETSAPGEQPQFLGVREQRVTGIIVFILTGISVFLAPILKCIPLPVLYGVFLYMGVASL 968

Query: 746  GGIQFWDRCILLLKPVKHHPQLPYVRRVPTLKMHMYTLIQVGGVVVLYAVKSSRFSLALP 805
             GIQFW+RC L L P KH P   ++R VP  ++H++TL+Q+  + VL+ +KS+  ++  P
Sbjct: 969  NGIQFWERCKLFLMPAKHQPDHAFLRHVPLRRIHLFTLVQILCLAVLWILKSTVAAIIFP 1028

Query: 806  FFLVLMVPLRMSLVYIFTPLQLRALDGAQKDIDKDD 841
              ++ ++ +R  L +IF+   L  +D    + +K +
Sbjct: 1029 VMILGLIIVRRLLDFIFSQHDLAWIDNILPEKEKKE 1064


>AF452248-1|AAL48291.1| 1051|Homo sapiens sodium bicarbonate
            cotransporter NBC4e protein.
          Length = 1051

 Score =  425 bits (1048), Expect = e-118
 Identities = 263/798 (32%), Positives = 423/798 (53%), Gaps = 69/798 (8%)

Query: 74   LAHA-SESQDELRRTHN-----DSILKRIPDDAEATTVLVGAVGFLDQPTIAFVRLAEGI 127
            L HA S S +++  T N     +  +K+IP D+EA+ VLVG V FLDQP IAFVRL +  
Sbjct: 270  LCHAQSRSMNDISLTPNTDQRKNKFMKKIPKDSEASNVLVGEVDFLDQPFIAFVRLIQSA 329

Query: 128  YMPSITEVPVPVRFMFILLGPGGADLDYHEVGRSISTLMSNPAFHSIAYKADDRRELLSA 187
             +  +TEVPVP RF+FILLGP G    Y+E+GR+I+TLM +  F  +AYKA +R +L++ 
Sbjct: 330  MLGGVTEVPVPTRFLFILLGPSGRAKSYNEIGRAIATLMVDDLFSDVAYKARNREDLIAG 389

Query: 188  INEFLDDSIVLPPGDWERQALLPLEELRAKSEMIRRRKINALE-----RKRIVADGDKPS 242
            I+EFLD+ IVLPPG+W+    + +E  +      +R+ + +L         +   G  P 
Sbjct: 390  IDEFLDEVIVLPPGEWDPN--IRIEPPKKVPSADKRKSVFSLAELGQMNGSVGGGGGAPG 447

Query: 243  DEKKALLAAEAGG-----------------MPP-EEPDDPLSRTGRLFGGVIRDMKRRYP 284
                      +GG                 MP   E  + L  TGR FGG+  D+KR+ P
Sbjct: 448  GGNGGGGGGGSGGGAGSGGAGGTSSGDDGEMPAMHEIGEELIWTGRFFGGLCLDIKRKLP 507

Query: 285  FYVSDFVDALNGQCVAATIFMYFAAVSSAITFGGLLAEKTYGKIGISETLSSGYVRSAVE 344
            ++ SDF D  + Q ++A +F+Y   +++AITFGGLL + T    G+ E+           
Sbjct: 508  WFPSDFYDGFHIQSISAILFIYLGCITNAITFGGLLGDATDNYQGVMESF---------- 557

Query: 345  GDLQVFTSAGGVLFALVAGQPMMITGATGPLLLLDESLANFCHSYGFDFLAARMYCGLWM 404
                + T+  G LF L +GQP++I  +TGP+L+ ++ L +F    G D++  R++ GL+ 
Sbjct: 558  ----LGTAMAGSLFCLFSGQPLIILSSTGPILIFEKLLFDFSKGNGLDYMEFRLWIGLYS 613

Query: 405  IVIALCVASVEGSVAVKKITRFTEDXXXXXXXXXXXXEPITSTIAVYRANPLGIDYCQFR 464
             V  L + + + S  +K ITRFTE+            + I   I  ++  P+ +D+    
Sbjct: 614  AVQCLILVATDASFIIKYITRFTEEGFSTLISFIFIYDAIKKMIGAFKYYPINMDFKPNF 673

Query: 465  EVALSNSTVQPLLNSTSVGNSSV-VAPAPPVSRLPPQPNTALFCTMLTLATFVLAYYLRI 523
                    V P   +T+V N+S  + P    S       TAL  ++L+     L+Y  R+
Sbjct: 674  ITTYKCECVAPDTVNTTVFNASAPLTPDTNASLYNLLNLTALDWSLLSKKE-CLSYGGRL 732

Query: 524  FRNG-KFLGRSSATSRVQVTGRDGI---------------QARRALGDFGVPIAIVLMVG 567
              N  KF+   +  S +   G   +               + R  + DF +  +I++  G
Sbjct: 733  LGNSCKFIPDLALMSFILFFGTYSMTLTLKKFKFSRYFPTKVRALVADFSIVFSILMFCG 792

Query: 568  ISCLVPVKTETLVVPAGLNPTTV-RSWFV-PLNPGLETIXXXXXXXXXXXXXXVYIIVFM 625
            I     ++T  L VP+ + PT   R WFV P       +              V I++FM
Sbjct: 793  IDACFGLETPKLHVPSVIKPTRPDRGWFVAPFGKNPWWV----YPASILPALLVTILIFM 848

Query: 626  ETHIAELIIAKPERRLKKGSGFHMDIVIMSFVNALCGMFGAPWQCVATVRSVSHVSALTI 685
            +  I  +I+ + E +LKK +G+H+D+  +  + ALC   G PW   A V S++H+ +L +
Sbjct: 849  DQQITAVIVNRKENKLKKAAGYHLDLFWVGILMALCSFMGLPWYVAAMVISIAHIDSLKM 908

Query: 686  MSTTHAPGDKPHIVEVKEQRLTGLLVAVMVGISVLASGWLCLVPMAVLFGVFLYMGISAL 745
             + T APG++P  + V+EQR+TG++V ++ GISV  +  L  +P+ VL+GVFLYMG+++L
Sbjct: 909  ETETSAPGEQPQFLRVREQRVTGIIVFILTGISVFLAPILKCIPLPVLYGVFLYMGVASL 968

Query: 746  GGIQFWDRCILLLKPVKHHPQLPYVRRVPTLKMHMYTLIQVGGVVVLYAVKSSRFSLALP 805
             GIQFW+RC L L P KH P   ++R VP  ++H++TL+Q+  + VL+ +KS+  ++  P
Sbjct: 969  NGIQFWERCKLFLMPAKHQPDHAFLRHVPLRRIHLFTLVQILCLAVLWILKSTVAAIIFP 1028

Query: 806  FFLVLMVPLRMSLVYIFT 823
              ++ ++ +R  L +IF+
Sbjct: 1029 VMILGLIIVRRLLDFIFS 1046


>AF243499-1|AAK26741.1| 1137|Homo sapiens sodium bicarbonate
            cotransporter NBC4a protein.
          Length = 1137

 Score =  411 bits (1012), Expect = e-114
 Identities = 267/832 (32%), Positives = 430/832 (51%), Gaps = 85/832 (10%)

Query: 74   LAHA-SESQDELRRTHN-----DSILKRIPDDAEATTVLVGAVGFLDQPTIAFVRLAEGI 127
            L HA S S +++  T N     +  +K+IP D+EA+ VLVG V FLDQP IAFVRL +  
Sbjct: 270  LCHAQSRSMNDISLTPNTDQRKNKFMKKIPKDSEASNVLVGEVDFLDQPFIAFVRLIQSA 329

Query: 128  YMPSITEVPVPVRFMFILLGPGGADLDYHEVGRSISTLMSNPAFHSIAYKADDRRELLSA 187
             +  +TEVPVP RF+FILLGP G    Y+E+GR+I+TLM +  F  +AYKA +R +L++ 
Sbjct: 330  MLGGVTEVPVPTRFLFILLGPSGRAKSYNEIGRAIATLMVDDLFSDVAYKARNREDLIAG 389

Query: 188  INEFLDDSIVLPPGDWERQALLPLEELRAKSEMIRRRKINALE-----RKRIVADGDKPS 242
            I+EFLD+ IVLPPG+W+    + +E  +      +R+ + +L         +   G  P 
Sbjct: 390  IDEFLDEVIVLPPGEWDPN--IRIEPPKKVPSADKRKSVFSLAELGQMNGSVGGGGGAPG 447

Query: 243  DEKKALLAAEAGG-----------------MPP-EEPDDPLSRTGRLFGGVIRDMKRRYP 284
                      +GG                 MP   E  + L  TGR FGG+  D+KR+ P
Sbjct: 448  GGNGGGGGGGSGGGAGSGGAGGTSSGDDGEMPAMHEIGEELIWTGRFFGGLCLDIKRKLP 507

Query: 285  FYVSDFVDALNGQCVAATIFMYFAAVSSAITFGGLLAEKTYGKIGISETLSSGYVRSAVE 344
            ++ SDF D  + Q ++A +F+Y   +++AITFGGLL + T    G+ E+           
Sbjct: 508  WFPSDFYDGFHIQSISAILFIYLGCITNAITFGGLLGDATDNYQGVMESF---------- 557

Query: 345  GDLQVFTSAGGVLFALVAGQPMMITGATGPLLLLDESLANFCHSYGFDFLAARMYCGLWM 404
                + T+  G LF L +GQP++I  +TGP+L+ ++ L +F    G D++  R++ GL  
Sbjct: 558  ----LGTAMAGSLFCLFSGQPLIILSSTGPILIFEKLLFDFSKGNGLDYMEFRLWIGLHS 613

Query: 405  IVIALCVASVEGSVAVKKITRFTEDXXXXXXXXXXXXEPITSTIAVYRANPLGIDYCQFR 464
             V  L + + + S  +K ITRFTE+            + I   I  ++  P+ +D+    
Sbjct: 614  AVQCLILVATDASFIIKYITRFTEEGFSTLISFIFIYDAIKKMIGAFKYYPINMDFKPNF 673

Query: 465  EVALSNSTVQPLLNSTSVGNSSV-VAPAPPVSRLPPQPNTALFCTMLTLATFVLAYYLRI 523
                    V P   +T+V N+S  +AP    S       TAL  ++L+     L+Y  R+
Sbjct: 674  ITTYKCECVAPDTVNTTVFNASAPLAPDTNASLYNLLNLTALDWSLLSKKE-CLSYGGRL 732

Query: 524  FRNG-KFLGRSSATSRVQVTGRDGI---------------QARRALGDFGVPIAIVLMVG 567
              N  KF+   +  S +   G   +               + R  + DF +  +I++  G
Sbjct: 733  LGNSCKFIPDLALMSFILFFGTYSMTLTLKKFKFSRYFPTKVRALVADFSIVFSILMFCG 792

Query: 568  ISCLVPVKTETLVVPAGLNPTTV-RSWFV-PLNPGLETIXXXXXXXXXXXXXXVYIIVFM 625
            I     ++T  L VP+ + P    R WFV P       +              V I++FM
Sbjct: 793  IDACFGLETPKLHVPSVIKPPRPDRGWFVAPFGKNPWWV----YPASILPALLVTILIFM 848

Query: 626  ETHIAELIIAKPERRLKKGSGFHMDIVIMSFVNALCGMFGAPWQCVATVRSVSHVSALTI 685
            +  I  +I+ + E +LKK +G+H+D+  +  + ALC   G PW   ATV S++H+ +L +
Sbjct: 849  DQQITAVIVNRKENKLKKAAGYHLDLFWVGILMALCSFMGLPWYVAATVISIAHIDSLKM 908

Query: 686  MSTTHAPGDKPHIVEVKEQRLTGLLVAVMVGISVLASGWLCLVPMAVLFGVFLYMGISAL 745
             + T APG++P  + V+EQR+TG++V ++ GISV  +  L  +P+ VL+GVFLYMG+++L
Sbjct: 909  ETETSAPGEQPQFLGVREQRVTGIIVFILTGISVFLAPILKCIPLPVLYGVFLYMGVASL 968

Query: 746  GGIQ----------------FWDRCILLLKPVKHHPQLPYVRRVPTLKMHMYTLIQVGGV 789
             GIQ                FW+RC L L P KH P   ++R VP  ++H++TL+Q+  +
Sbjct: 969  NGIQMGTGGSEFKIQKKLTPFWERCKLFLMPAKHQPDHAFLRHVPLRRIHLFTLVQILCL 1028

Query: 790  VVLYAVKSSRFSLALPFFLVLMVPLRMSLVYIFTPLQLRALDGAQKDIDKDD 841
             VL+ +KS+  ++  P  ++ ++ +R  L +IF+   L  +D    + +K +
Sbjct: 1029 AVLWILKSTVAAIIFPVMILGLIIVRRLLDFIFSQHDLAWIDNILPEKEKKE 1080


>AF332961-1|AAK69625.1|  959|Homo sapiens anion exchanger AE4
           protein.
          Length = 959

 Score =  404 bits (995), Expect = e-112
 Identities = 266/810 (32%), Positives = 428/810 (52%), Gaps = 70/810 (8%)

Query: 46  LLNLSERRRRSTHARPSAAGLDPREVEYLAHASESQDE-LRRTHNDSILKRIPDDAEATT 104
           LL   +   ++T  RP      PR+      AS++++  LR    + + +++P  AEA T
Sbjct: 151 LLQRPQHYNQTTGTRPCWGSTHPRK------ASDNEEAPLREQCQNPLRQKLPPGAEAGT 204

Query: 105 VLVGAVGFLDQPTIAFVRLAEGIYMPSITEVPVPVRFMFILLGPGGADLDYHEVGRSIST 164
           VL G +GFL QP  AFVRL   + + S+TEV +P RF  +LLGP      YHE+GR+ + 
Sbjct: 205 VLAGELGFLAQPLGAFVRLRNPVVLGSLTEVSLPSRFFCLLLGPCMLGKGYHEMGRAAAV 264

Query: 165 LMSNPAFHSIAYKADDRRELLSAINEFLDDSIVLPPGDWERQALLPLEE-LRAKSEMI-- 221
           L+S+P F     +A +  +LL+A++ FL++  VLPPG W+  A +P  + L ++ + +  
Sbjct: 265 LLSDPQFQWSVRRASNLHDLLAALDAFLEEVTVLPPGRWDPTARIPPPKCLPSQHKRLPS 324

Query: 222 RRRKINALERKRIVADGDKPSDEKKALLAAEAGGMPPEEPDDPLSRTGRLFGGVIRDMKR 281
           ++R+I      R+ +  D+              G     P+  L RTGRLFGG+I+D++R
Sbjct: 325 QQREIRGPAVPRLTSAEDR-----------HRHGPHAHSPE--LQRTGRLFGGLIQDVRR 371

Query: 282 RYPFYVSDFVDALNGQCVAATIFMYFAAVSSAITFGGLLAEKTYGKIGISETLSSGYVRS 341
           + P+Y SDF+DAL+ QC +A +++Y A V++AITFGGLL + T G  G+ E+        
Sbjct: 372 KVPWYPSDFLDALHLQCFSAVLYIYLATVTNAITFGGLLGDATDGAQGVLESFLG----- 426

Query: 342 AVEGDLQVFTSAGGVLFALVAGQPMMITGATGPLLLLDESLANFCHSYGFDFLAARMYCG 401
                    T+  G  F L+AGQP+ I  +TGP+L+ +  L +F   Y  D+L  R++ G
Sbjct: 427 ---------TAVAGAAFCLMAGQPLTILSSTGPVLVFERLLFSFSRDYSLDYLPFRLWVG 477

Query: 402 LWMIVIALCVASVEGSVAVKKITRFTEDXXXXXXXXXXXXEPITSTIAVYRANPL----G 457
           +W+    L + + E SV V+  TRFTE+            + +   + +    P+     
Sbjct: 478 IWVATFCLVLVATEASVLVRYFTRFTEEGFCALISLIFIYDAVGKMLNLTHTYPIQKPGS 537

Query: 458 IDY---CQFREVALSNST---VQPL----LNSTSVG--NSSVVAPAPPVSRLPPQPNTAL 505
             Y   CQ+     + S     +P     + S  +G  N+S++ P P  +R    P    
Sbjct: 538 SAYGCLCQYPGPGGNESQWIRTRPKDRDDIVSMDLGLINASLLPP-PECTRQGGHPRGPG 596

Query: 506 FCTMLTLATFVLAYYLRIFRNGKFLGRSSATSRVQVTGRDGIQARRALGDFGVPIAIVLM 565
             T+  +A F L  +L  F     L +   TSR   +       R+ L DF   +AI+L 
Sbjct: 597 CHTVPDIAFFSLLLFLTSFFFAMAL-KCVKTSRFFPS-----VVRKGLSDFSSVLAILLG 650

Query: 566 VGISCLVPVKTETLVVPAGLNPTTV-RSWFVP---LNPGLETIXXXXXXXXXXXXXXVYI 621
            G+   + + T  L+VP    PT   R W V     NP   ++                I
Sbjct: 651 CGLDAFLGLATPKLMVPREFKPTLPGRGWLVSPFGANPWWWSVAAALPALLLS------I 704

Query: 622 IVFMETHIAELIIAKPERRLKKGSGFHMDIVIMSFVNALCGMFGAPWQCVATVRSVSHVS 681
           ++FM+  I  +I+ + E RL+KG+GFH+D+  ++ +  L    G PW   ATV S++H+ 
Sbjct: 705 LIFMDQQITAVILNRMEYRLQKGAGFHLDLFCVAVLMLLTSALGLPWYVSATVISLAHMD 764

Query: 682 ALTIMSTTHAPGDKPHIVEVKEQRLTGLLVAVMVGISVLASGWLCLVPMAVLFGVFLYMG 741
           +L   S   APG++P+ + ++EQRLTGL+V ++ G S+  +  L  +PM VL+G+FLYMG
Sbjct: 765 SLRRESRACAPGERPNFLGIREQRLTGLVVFILTGASIFLAPVLKFIPMPVLYGIFLYMG 824

Query: 742 ISALGGIQFWDRCILLLKPVKHHPQLPYVRRVPTLKMHMYTLIQVGGVVVLYAVKSSRFS 801
           ++AL  IQF +R  LLL P KH P L  +R VP  ++H++T IQ+  + +L+ +KS+  +
Sbjct: 825 VAALSSIQFTNRVKLLLMPAKHQPDLLLLRHVPLTRVHLFTAIQLACLGLLWIIKSTPAA 884

Query: 802 LALPFFLVLMVPLRMSLVYIFTPLQLRALD 831
           +  P  L+ +V +R +L  +F+P +L  LD
Sbjct: 885 IIFPLMLLGLVGVRKALERVFSPQELLWLD 914


>AF313465-1|AAK28832.1|  990|Homo sapiens sodium bicarbonate
           cotransporter protein.
          Length = 990

 Score =  404 bits (995), Expect = e-112
 Identities = 266/810 (32%), Positives = 428/810 (52%), Gaps = 70/810 (8%)

Query: 46  LLNLSERRRRSTHARPSAAGLDPREVEYLAHASESQDE-LRRTHNDSILKRIPDDAEATT 104
           LL   +   ++T  RP      PR+      AS++++  LR    + + +++P  AEA T
Sbjct: 182 LLQRPQHYNQTTGTRPCWGSTHPRK------ASDNEEAPLREQCQNPLRQKLPPGAEAGT 235

Query: 105 VLVGAVGFLDQPTIAFVRLAEGIYMPSITEVPVPVRFMFILLGPGGADLDYHEVGRSIST 164
           VL G +GFL QP  AFVRL   + + S+TEV +P RF  +LLGP      YHE+GR+ + 
Sbjct: 236 VLAGELGFLAQPLGAFVRLRNPVVLGSLTEVSLPSRFFCLLLGPCMLGKGYHEMGRAAAV 295

Query: 165 LMSNPAFHSIAYKADDRRELLSAINEFLDDSIVLPPGDWERQALLPLEE-LRAKSEMI-- 221
           L+S+P F     +A +  +LL+A++ FL++  VLPPG W+  A +P  + L ++ + +  
Sbjct: 296 LLSDPQFQWSVRRASNLHDLLAALDAFLEEVTVLPPGRWDPTARIPPPKCLPSQHKRLPS 355

Query: 222 RRRKINALERKRIVADGDKPSDEKKALLAAEAGGMPPEEPDDPLSRTGRLFGGVIRDMKR 281
           ++R+I      R+ +  D+              G     P+  L RTGRLFGG+I+D++R
Sbjct: 356 QQREIRGPAVPRLTSAEDR-----------HRHGPHAHSPE--LQRTGRLFGGLIQDVRR 402

Query: 282 RYPFYVSDFVDALNGQCVAATIFMYFAAVSSAITFGGLLAEKTYGKIGISETLSSGYVRS 341
           + P+Y SDF+DAL+ QC +A +++Y A V++AITFGGLL + T G  G+ E+        
Sbjct: 403 KVPWYPSDFLDALHLQCFSAVLYIYLATVTNAITFGGLLGDATDGAQGVLESFLG----- 457

Query: 342 AVEGDLQVFTSAGGVLFALVAGQPMMITGATGPLLLLDESLANFCHSYGFDFLAARMYCG 401
                    T+  G  F L+AGQP+ I  +TGP+L+ +  L +F   Y  D+L  R++ G
Sbjct: 458 ---------TAVAGAAFCLMAGQPLTILSSTGPVLVFERLLFSFSRDYSLDYLPFRLWVG 508

Query: 402 LWMIVIALCVASVEGSVAVKKITRFTEDXXXXXXXXXXXXEPITSTIAVYRANPL----G 457
           +W+    L + + E SV V+  TRFTE+            + +   + +    P+     
Sbjct: 509 IWVATFCLVLVATEASVLVRYFTRFTEEGFCALISLIFIYDAVGKMLNLTHTYPIQKPGS 568

Query: 458 IDY---CQFREVALSNST---VQPL----LNSTSVG--NSSVVAPAPPVSRLPPQPNTAL 505
             Y   CQ+     + S     +P     + S  +G  N+S++ P P  +R    P    
Sbjct: 569 SAYGCLCQYPGPGGNESQWIRTRPKDRDDIVSMDLGLINASLLPP-PECTRQGGHPRGPG 627

Query: 506 FCTMLTLATFVLAYYLRIFRNGKFLGRSSATSRVQVTGRDGIQARRALGDFGVPIAIVLM 565
             T+  +A F L  +L  F     L +   TSR   +       R+ L DF   +AI+L 
Sbjct: 628 CHTVPDIAFFSLLLFLTSFFFAMAL-KCVKTSRFFPS-----VVRKGLSDFSSVLAILLG 681

Query: 566 VGISCLVPVKTETLVVPAGLNPTTV-RSWFVP---LNPGLETIXXXXXXXXXXXXXXVYI 621
            G+   + + T  L+VP    PT   R W V     NP   ++                I
Sbjct: 682 CGLDAFLGLATPKLMVPREFKPTLPGRGWLVSPFGANPWWWSVAAALPALLLS------I 735

Query: 622 IVFMETHIAELIIAKPERRLKKGSGFHMDIVIMSFVNALCGMFGAPWQCVATVRSVSHVS 681
           ++FM+  I  +I+ + E RL+KG+GFH+D+  ++ +  L    G PW   ATV S++H+ 
Sbjct: 736 LIFMDQQITAVILNRMEYRLQKGAGFHLDLFCVAVLMLLTSALGLPWYVSATVISLAHMD 795

Query: 682 ALTIMSTTHAPGDKPHIVEVKEQRLTGLLVAVMVGISVLASGWLCLVPMAVLFGVFLYMG 741
           +L   S   APG++P+ + ++EQRLTGL+V ++ G S+  +  L  +PM VL+G+FLYMG
Sbjct: 796 SLRRESRACAPGERPNFLGIREQRLTGLVVFILTGASIFLAPVLKFIPMPVLYGIFLYMG 855

Query: 742 ISALGGIQFWDRCILLLKPVKHHPQLPYVRRVPTLKMHMYTLIQVGGVVVLYAVKSSRFS 801
           ++AL  IQF +R  LLL P KH P L  +R VP  ++H++T IQ+  + +L+ +KS+  +
Sbjct: 856 VAALSSIQFTNRVKLLLMPAKHQPDLLLLRHVPLTRVHLFTAIQLACLGLLWIIKSTPAA 915

Query: 802 LALPFFLVLMVPLRMSLVYIFTPLQLRALD 831
           +  P  L+ +V +R +L  +F+P +L  LD
Sbjct: 916 IIFPLMLLGLVGVRKALERVFSPQELLWLD 945


>AB032762-1|BAA93010.1|  957|Homo sapiens sodium bicarbonate
           cotransporter 5 protein.
          Length = 957

 Score =  404 bits (995), Expect = e-112
 Identities = 266/810 (32%), Positives = 428/810 (52%), Gaps = 70/810 (8%)

Query: 46  LLNLSERRRRSTHARPSAAGLDPREVEYLAHASESQDE-LRRTHNDSILKRIPDDAEATT 104
           LL   +   ++T  RP      PR+      AS++++  LR    + + +++P  AEA T
Sbjct: 149 LLQRPQHYNQTTGTRPCWGSTHPRK------ASDNEEAPLREQCQNPLRQKLPPGAEAGT 202

Query: 105 VLVGAVGFLDQPTIAFVRLAEGIYMPSITEVPVPVRFMFILLGPGGADLDYHEVGRSIST 164
           VL G +GFL QP  AFVRL   + + S+TEV +P RF  +LLGP      YHE+GR+ + 
Sbjct: 203 VLAGELGFLAQPLGAFVRLRNPVVLGSLTEVSLPSRFFCLLLGPCMLGKGYHEMGRAAAV 262

Query: 165 LMSNPAFHSIAYKADDRRELLSAINEFLDDSIVLPPGDWERQALLPLEE-LRAKSEMI-- 221
           L+S+P F     +A +  +LL+A++ FL++  VLPPG W+  A +P  + L ++ + +  
Sbjct: 263 LLSDPQFQWSVRRASNLHDLLAALDAFLEEVTVLPPGRWDPTARIPPPKCLPSQHKRLPS 322

Query: 222 RRRKINALERKRIVADGDKPSDEKKALLAAEAGGMPPEEPDDPLSRTGRLFGGVIRDMKR 281
           ++R+I      R+ +  D+              G     P+  L RTGRLFGG+I+D++R
Sbjct: 323 QQREIRGPAVPRLTSAEDR-----------HRHGPHAHSPE--LQRTGRLFGGLIQDVRR 369

Query: 282 RYPFYVSDFVDALNGQCVAATIFMYFAAVSSAITFGGLLAEKTYGKIGISETLSSGYVRS 341
           + P+Y SDF+DAL+ QC +A +++Y A V++AITFGGLL + T G  G+ E+        
Sbjct: 370 KVPWYPSDFLDALHLQCFSAVLYIYLATVTNAITFGGLLGDATDGAQGVLESFLG----- 424

Query: 342 AVEGDLQVFTSAGGVLFALVAGQPMMITGATGPLLLLDESLANFCHSYGFDFLAARMYCG 401
                    T+  G  F L+AGQP+ I  +TGP+L+ +  L +F   Y  D+L  R++ G
Sbjct: 425 ---------TAVAGAAFCLMAGQPLTILSSTGPVLVFERLLFSFSRDYSLDYLPFRLWVG 475

Query: 402 LWMIVIALCVASVEGSVAVKKITRFTEDXXXXXXXXXXXXEPITSTIAVYRANPL----G 457
           +W+    L + + E SV V+  TRFTE+            + +   + +    P+     
Sbjct: 476 IWVATFCLVLVATEASVLVRYFTRFTEEGFCALISLIFIYDAVGKMLNLTHTYPIQKPGS 535

Query: 458 IDY---CQFREVALSNST---VQPL----LNSTSVG--NSSVVAPAPPVSRLPPQPNTAL 505
             Y   CQ+     + S     +P     + S  +G  N+S++ P P  +R    P    
Sbjct: 536 SAYGCLCQYPGPGGNESQWIRTRPKDRDDIVSMDLGLINASLLPP-PECTRQGGHPRGPG 594

Query: 506 FCTMLTLATFVLAYYLRIFRNGKFLGRSSATSRVQVTGRDGIQARRALGDFGVPIAIVLM 565
             T+  +A F L  +L  F     L +   TSR   +       R+ L DF   +AI+L 
Sbjct: 595 CHTVPDIAFFSLLLFLTSFFFAMAL-KCVKTSRFFPS-----VVRKGLSDFSSVLAILLG 648

Query: 566 VGISCLVPVKTETLVVPAGLNPTTV-RSWFVP---LNPGLETIXXXXXXXXXXXXXXVYI 621
            G+   + + T  L+VP    PT   R W V     NP   ++                I
Sbjct: 649 CGLDAFLGLATPKLMVPREFKPTLPGRGWLVSPFGANPWWWSVAAALPALLLS------I 702

Query: 622 IVFMETHIAELIIAKPERRLKKGSGFHMDIVIMSFVNALCGMFGAPWQCVATVRSVSHVS 681
           ++FM+  I  +I+ + E RL+KG+GFH+D+  ++ +  L    G PW   ATV S++H+ 
Sbjct: 703 LIFMDQQITAVILNRMEYRLQKGAGFHLDLFCVAVLMLLTSALGLPWYVSATVISLAHMD 762

Query: 682 ALTIMSTTHAPGDKPHIVEVKEQRLTGLLVAVMVGISVLASGWLCLVPMAVLFGVFLYMG 741
           +L   S   APG++P+ + ++EQRLTGL+V ++ G S+  +  L  +PM VL+G+FLYMG
Sbjct: 763 SLRRESRACAPGERPNFLGIREQRLTGLVVFILTGASIFLAPVLKFIPMPVLYGIFLYMG 822

Query: 742 ISALGGIQFWDRCILLLKPVKHHPQLPYVRRVPTLKMHMYTLIQVGGVVVLYAVKSSRFS 801
           ++AL  IQF +R  LLL P KH P L  +R VP  ++H++T IQ+  + +L+ +KS+  +
Sbjct: 823 VAALSSIQFTNRVKLLLMPAKHQPDLLLLRHVPLTRVHLFTAIQLACLGLLWIIKSTPAA 882

Query: 802 LALPFFLVLMVPLRMSLVYIFTPLQLRALD 831
           +  P  L+ +V +R +L  +F+P +L  LD
Sbjct: 883 IIFPLMLLGLVGVRKALERVFSPQELLWLD 912


>AF207661-1|AAG18492.1| 1074|Homo sapiens sodium bicarbonate
            cotransporter-like protein protein.
          Length = 1074

 Score =  403 bits (993), Expect = e-111
 Identities = 261/796 (32%), Positives = 413/796 (51%), Gaps = 85/796 (10%)

Query: 74   LAHA-SESQDELRRTHN-----DSILKRIPDDAEATTVLVGAVGFLDQPTIAFVRLAEGI 127
            L HA S S +++  T N     +  +K+IP D+EA+ VLVG V FLDQP IAFVRL +  
Sbjct: 270  LCHAQSRSMNDISLTPNTDQRKNKFMKKIPKDSEASNVLVGEVDFLDQPFIAFVRLIQSA 329

Query: 128  YMPSITEVPVPVRFMFILLGPGGADLDYHEVGRSISTLMSNPAFHSIAYKADDRRELLSA 187
             +  +TEVPVP RF+FILLGP G    Y+E+GR+I+TLM +  F  +AYKA +R +L++ 
Sbjct: 330  MLGGVTEVPVPTRFLFILLGPSGRAKSYNEIGRAIATLMVDDLFSDVAYKARNREDLIAG 389

Query: 188  INEFLDDSIVLPPGDWERQALLPLEELRAKSEMIRRRKINALE-----RKRIVADGDKPS 242
            I+EFLD+ IVLPPG+W+    + +E  +      +R+ + +L         +   G  P 
Sbjct: 390  IDEFLDEVIVLPPGEWDPN--IRIEPPKKVPSADKRKSVFSLAELGQMNGSVGGGGGAPG 447

Query: 243  DEKKALLAAEAGG-----------------MPP-EEPDDPLSRTGRLFGGVIRDMKRRYP 284
                      +GG                 MP   E  + L  TGR FGG+  D+KR+ P
Sbjct: 448  GGNGGGGGGGSGGGAGSGGAGGTSSGDDGEMPAMHEIGEELIWTGRFFGGLCLDIKRKLP 507

Query: 285  FYVSDFVDALNGQCVAATIFMYFAAVSSAITFGGLLAEKTYGKIGISETLSSGYVRSAVE 344
            ++ SDF D  + Q ++A +F+Y   +++AITFGGLL + T    G+ E+           
Sbjct: 508  WFPSDFYDGFHIQSISAILFIYLGCITNAITFGGLLGDATDNYQGVMESF---------- 557

Query: 345  GDLQVFTSAGGVLFALVAGQPMMITGATGPLLLLDESLANFCHSYGFDFLAARMYCGLWM 404
                + T+  G LF L +GQP++I  +TGP+L+ ++ L +F    G D++  R++ GL  
Sbjct: 558  ----LGTAMAGSLFCLFSGQPLIILSSTGPILIFEKLLFDFSKGNGLDYMEFRLWIGLHS 613

Query: 405  IVIALCVASVEGSVAVKKITRFTEDXXXXXXXXXXXXEPITSTIAVYRANPLGIDYCQFR 464
             V  L + + + S  +K ITRFTE+            + I   I  ++  P+ +D+    
Sbjct: 614  AVQCLILVATDASFIIKYITRFTEEGFSTLISFIFIYDAIKKMIGAFKYYPINMDFKPNF 673

Query: 465  EVALSNSTVQPLLNSTSVGNSSV-VAPAPPVSRLPPQPNTALFCTMLTLATFVLAYYLRI 523
                    V P   +T+V N+S  +AP    S       TAL  ++L+     L+Y  R+
Sbjct: 674  ITTYKCECVAPDTVNTTVFNASAPLAPDTNASLYNLLNLTALDWSLLSKKE-CLSYGGRL 732

Query: 524  FRNG-KFLGRSSATSRVQVTGRDGI---------------QARRALGDFGVPIAIVLMVG 567
              N  KF+   +  S +   G   +               + R  + DF +  +I++  G
Sbjct: 733  LGNSCKFIPDLALMSFILFFGTYSMTLTLKKFKFSRYFPTKVRALVADFSIVFSILMFCG 792

Query: 568  ISCLVPVKTETLVVPAGLNPTTV-RSWFV-PLNPGLETIXXXXXXXXXXXXXXVYIIVFM 625
            I     ++T  L VP+ + PT   R WFV P       +              V I++FM
Sbjct: 793  IDACFGLETPKLHVPSVIKPTRPDRGWFVAPFGKNPWWV----YPASILPALLVTILIFM 848

Query: 626  ETHIAELIIAKPERRLKKGSGFHMDIVIMSFVNALCGMFGAPWQCVATVRSVSHVSALTI 685
            +  I  +I+ + E +LKK +G+H+D+  +  + ALC   G PW   ATV S++H+ +L +
Sbjct: 849  DQQITAVIVNRKENKLKKAAGYHLDLFWVGILMALCSFMGLPWYVAATVISIAHIDSLKM 908

Query: 686  MSTTHAPGDKPHIVEVKEQRLTGLLVAVMVGISVLASGWLCLVPMAVLFGVFLYMGISAL 745
             + T APG++P  + V+EQR+TG++V ++ GISV  +  L  +P+ VL+GVFLYMG+++L
Sbjct: 909  ETETSAPGEQPQFLGVREQRVTGIIVFILTGISVFLAPILKCIPLPVLYGVFLYMGVASL 968

Query: 746  GGIQ----------------FWDRCILLLKPVKHHPQLPYVRRVPTLKMHMYTLIQVGGV 789
             GIQ                FW+RC L L P KH P   ++R VP  ++H++TL+Q+  +
Sbjct: 969  NGIQMGTGGSEFKIQKKLTPFWERCKLFLMPAKHQPDHAFLRHVPLRRIHLFTLVQILCL 1028

Query: 790  VVLYAVKSSRFSLALP 805
             VL+ +KS+  ++  P
Sbjct: 1029 AVLWILKSTVAAIIFP 1044


>BC109221-1|AAI09222.1| 1019|Homo sapiens SLC4A5 protein protein.
          Length = 1019

 Score =  399 bits (983), Expect = e-110
 Identities = 255/801 (31%), Positives = 412/801 (51%), Gaps = 77/801 (9%)

Query: 74  LAHA-SESQDELRRTHN-----DSILKRIPDDAEATTVLVGAVGFLDQPTIAFVRLAEGI 127
           L HA S S +++  T N     +  +K+IP D+EA+ VLVG V FLDQP IAFVRL +  
Sbjct: 206 LCHAQSRSMNDISLTPNTDQRKNKFMKKIPKDSEASNVLVGEVDFLDQPFIAFVRLIQSA 265

Query: 128 YMPSITEVPVPVRFMFILLGPGGADLDYHEVGRSISTLMSNPAFHSIAYKADDRRELLSA 187
            +  +TEVPVP RF+FILLGP G    Y+E+GR+I+TLM +  F  +AYKA +R +L++ 
Sbjct: 266 MLGGVTEVPVPTRFLFILLGPSGRAKSYNEIGRAIATLMVDDLFSDVAYKARNREDLIAG 325

Query: 188 INEFLDDSIVLPPGDWERQALLPLEELRAKSEMIRRRKINALE-----RKRIVADGDKPS 242
           I+EFLD+ IVLPPG+W+    + +E  +      +R+ + +L         +   G  P 
Sbjct: 326 IDEFLDEVIVLPPGEWDPN--IRIEPPKKVPSADKRKSVFSLAELGQMNGSVGGGGGAPG 383

Query: 243 DEKKALLAAEAGG-----------------MPP-EEPDDPLSRTGRLFGGVIRDMKRRYP 284
                     +GG                 MP   E  + L  TGR FGG+  D+KR+ P
Sbjct: 384 GGNGGGGGGGSGGGAGSGGAGGTSSGDDGEMPAMHEIGEELIWTGRFFGGLCLDIKRKLP 443

Query: 285 FYVSDFVDALNGQCVAATIFMYFAAVSSAITFGGLLAEKTYGKIGISETLSSGYVRSAVE 344
           ++ SDF D  + Q ++A +F+Y   +++AITFGGLL + T    G+ E+           
Sbjct: 444 WFPSDFYDGFHIQSISAILFIYLGCITNAITFGGLLGDATDNYQGVMESF---------- 493

Query: 345 GDLQVFTSAGGVLFALVAGQPMMITGATGPLLLLDESLANFCHSYGFDFLAARMYCGLWM 404
               + T+  G LF L +GQP++I  +TGP+L+ ++ L +F    G D++  R++ GL  
Sbjct: 494 ----LGTAMAGSLFCLFSGQPLIILSSTGPILIFEKLLFDFSKGNGLDYMEFRLWIGLHS 549

Query: 405 IVIALCVASVEGSVAVKKITRFTEDXXXXXXXXXXXXEPITSTIAVYRANPLGIDYCQFR 464
            V  L + + + S  +K ITRFTE+            + I   I  ++  P+ +D+    
Sbjct: 550 AVQCLILVATDASFIIKYITRFTEEGFSTLISFIFIYDAIKKMIGAFKYYPINMDFKPNF 609

Query: 465 EVALSNSTVQPLLNSTSVGNSSVVAPAPPVSRLPPQPNTALF--CTMLTLATFVLAYYLR 522
                   V P   +T+V N+S  AP      L P  N +L+    +  L   +L+    
Sbjct: 610 ITTYKCECVAPDTVNTTVFNAS--AP------LAPDTNASLYNLLNLTALDWSLLSKKEC 661

Query: 523 IFRNGKFLGRSSATSRVQVTGRDGIQARRALGDFGVPIAIVLMVGISCLVPVKTETLVVP 582
           +   G+ LG S                 + + D  +   I+     S  + +K       
Sbjct: 662 LSYGGRLLGNSC----------------KFIPDLALMSFILFFGTYSMTLTLKKFKFSRY 705

Query: 583 AGLNPTTV-RSWFV-PLNPGLETIXXXXXXXXXXXXXXVYIIVFMETHIAELIIAKPERR 640
               PT   R WFV P       +              +++    +  I  +I+ + E +
Sbjct: 706 FPTKPTRPDRGWFVAPFGKNPWWVYPASILPALLVTILIFM----DQQITAVIVNRKENK 761

Query: 641 LKKGSGFHMDIVIMSFVNALCGMFGAPWQCVATVRSVSHVSALTIMSTTHAPGDKPHIVE 700
           LKK +G+H+D+  +  + ALC   G PW   ATV S++H+ +L + + T APG++P  + 
Sbjct: 762 LKKAAGYHLDLFWVGILMALCSFMGLPWYVAATVISIAHIDSLKMETETSAPGEQPQFLG 821

Query: 701 VKEQRLTGLLVAVMVGISVLASGWLCLVPMAVLFGVFLYMGISALGGIQFWDRCILLLKP 760
           V+EQR+TG++V ++ GISV  +  L  +P+ VL+GVFLYMG+++L GIQFW+RC L L P
Sbjct: 822 VREQRVTGIIVFILTGISVFLAPILKCIPLPVLYGVFLYMGVASLNGIQFWERCKLFLMP 881

Query: 761 VKHHPQLPYVRRVPTLKMHMYTLIQVGGVVVLYAVKSSRFSLALPFFLVLMVPLRMSLVY 820
            KH P   ++R VP  ++H++TL+Q+  + VL+ +KS+  ++  P  ++ ++ +R  L +
Sbjct: 882 AKHQPDHAFLRHVPLRRIHLFTLVQILCLAVLWILKSTVAAIIFPVMILGLIIVRRLLDF 941

Query: 821 IFTPLQLRALDGAQKDIDKDD 841
           IF+   L  +D    + +K +
Sbjct: 942 IFSQHDLAWIDNILPEKEKKE 962


>AF336237-1|AAK16733.1|  945|Homo sapiens anion exchanger AE4
           protein.
          Length = 945

 Score =  375 bits (923), Expect = e-103
 Identities = 258/807 (31%), Positives = 416/807 (51%), Gaps = 78/807 (9%)

Query: 46  LLNLSERRRRSTHARPSAAGLDPREVEYLAHASESQDE-LRRTHNDSILKRIPDDAEATT 104
           LL   +   ++T  RP      PR+      AS++++  LR    + + +++P  AEA T
Sbjct: 151 LLQRPQHYNQTTGTRPCWGSTHPRK------ASDNEEAPLREQCQNPLRQKLPPGAEAGT 204

Query: 105 VLVGAVGFLDQPTIAFVRLAEGIYMPSITEVPVPVRFMFILLGPGGADLDYHEVGRSIST 164
           VL G +GFL QP  AFVRL   + + S+TEV +P RF  +LLGP      YHE+GR+ + 
Sbjct: 205 VLAGELGFLAQPLGAFVRLRNPVVLGSLTEVSLPSRFFCLLLGPCMLGKGYHEMGRAAAV 264

Query: 165 LMSNPAFHSIAYKADDRRELLSAINEFLDDSIVLPPGDWERQALLPLEE-LRAKSEMI-- 221
           L+S+P F     +A +  +LL+A++ FL++  VLPPG W+  A +P  + L ++ + +  
Sbjct: 265 LLSDPQFQWSVRRASNLHDLLAALDAFLEEVTVLPPGRWDPTARIPPPKCLPSQHKRLPS 324

Query: 222 RRRKINALERKRIVADGDKPSDEKKALLAAEAGGMPPEEPDDPLSRTGRLFGGVIRDMKR 281
           ++R+I      R+ +  D+              G     P+  L RTGR           
Sbjct: 325 QQREIRGPAVPRLTSAEDR-----------HRHGPHAHSPE--LQRTGR----------- 360

Query: 282 RYPFYVSDFVDALNGQCVAATIFMYFAAVSSAITFGGLLAEKTYGKIGISETLSSGYVRS 341
           + P+Y SDF+DAL+ QC +A +++Y A V++AITFGGLL + T G  G+ E+        
Sbjct: 361 KVPWYPSDFLDALHLQCFSAVLYIYLATVTNAITFGGLLGDATDGAQGVLESFLG----- 415

Query: 342 AVEGDLQVFTSAGGVLFALVAGQPMMITGATGPLLLLDESLANFCHSYGFDFLAARMYCG 401
                    T+  G  F L+AGQP+ I  +TGP+L+ +  L +F   Y  D+L  R++ G
Sbjct: 416 ---------TAMAGAAFCLMAGQPLTILSSTGPVLVFERLLFSFSRDYSLDYLPFRLWVG 466

Query: 402 LWMIVIALCVASVEGSVAVKKITRFTEDXXXXXXXXXXXXEPITSTIAVYRANPL----G 457
           +W+    L + + E SV V+  TRFTE+            + +   + +    P+     
Sbjct: 467 IWVATFCLVLVATEASVLVRYFTRFTEEGFCALISLIFIYDAVGKMLNLTHTYPIQKPGS 526

Query: 458 IDY---CQFREVALSNST---VQPL-LNSTSVG--NSSVVAPAPPVSRLPPQPNTALFCT 508
             Y   CQ+     + S     +P   +   +G  N+S++ P P  +R    P      T
Sbjct: 527 SAYGCLCQYPGPGGNESQWIRTRPKDRDDIDLGLINASLLPP-PECTRQGGHPRGPGCHT 585

Query: 509 MLTLATFVLAYYLRIFRNGKFLGRSSATSRVQVTGRDGIQARRALGDFGVPIAIVLMVGI 568
           +  +A F L  +L  F     L +   TSR   +       R+ L DF   +AI+L  G+
Sbjct: 586 VPDIAFFSLLLFLTSFFFAMAL-KCVKTSRFFPS-----VVRKGLSDFSSVLAILLGCGL 639

Query: 569 SCLVPVKTETLVVPAGLNPTTV-RSWFVP---LNPGLETIXXXXXXXXXXXXXXVYIIVF 624
              + + T  L+VP    PT   R W V     NP   ++                I++F
Sbjct: 640 DAFLGLATPKLMVPREFKPTLPGRGWLVSPFGANPWWWSVAAALPALLLS------ILIF 693

Query: 625 METHIAELIIAKPERRLKKGSGFHMDIVIMSFVNALCGMFGAPWQCVATVRSVSHVSALT 684
           M+  I  +I+ + E RL+KG+GFH+D+  ++ +  L    G PW   ATV S++H+ +L 
Sbjct: 694 MDQQITAVILNRMEYRLQKGAGFHLDLFCVAVLMLLTSALGLPWYVSATVISLAHMDSLR 753

Query: 685 IMSTTHAPGDKPHIVEVKEQRLTGLLVAVMVGISVLASGWLCLVPMAVLFGVFLYMGISA 744
             S   APG++P+ + ++EQRLTGL+V ++ G S+  +  L  +PM VL+G+FLYMG++A
Sbjct: 754 RESKACAPGERPNFLGIREQRLTGLVVFILTGASIFLAPVLKFIPMPVLYGIFLYMGVAA 813

Query: 745 LGGIQFWDRCILLLKPVKHHPQLPYVRRVPTLKMHMYTLIQVGGVVVLYAVKSSRFSLAL 804
           L  IQF +R  LLL P KH P L  +R VP  ++H++T IQ+  + +L+ +KS+  ++  
Sbjct: 814 LSSIQFTNRVKLLLMPAKHQPDLLLLRHVPLTRVHLFTAIQLACLGLLWIIKSTPAAIIF 873

Query: 805 PFFLVLMVPLRMSLVYIFTPLQLRALD 831
           P  L+ +V +R +L  +F+P +L  LD
Sbjct: 874 PLMLLGLVGVRKALERVFSPQELLWLD 900


>AF293338-1|AAK97073.1| 1040|Homo sapiens sodium bicarbonate
           cotransporter NBC4d protein.
          Length = 1040

 Score =  336 bits (826), Expect = 2e-91
 Identities = 225/708 (31%), Positives = 361/708 (50%), Gaps = 69/708 (9%)

Query: 74  LAHA-SESQDELRRTHN-----DSILKRIPDDAEATTVLVGAVGFLDQPTIAFVRLAEGI 127
           L HA S S +++  T N     +  +K+IP D+EA+ VLVG V FLDQP IAFVRL +  
Sbjct: 270 LCHAQSRSMNDISLTPNTDQRKNKFMKKIPKDSEASNVLVGEVDFLDQPFIAFVRLIQSA 329

Query: 128 YMPSITEVPVPVRFMFILLGPGGADLDYHEVGRSISTLMSNPAFHSIAYKADDRRELLSA 187
            +  +TEVPVP RF+FILLGP G    Y+E+GR+I+TLM +  F  +AYKA +R +L++ 
Sbjct: 330 MLGGVTEVPVPTRFLFILLGPSGRAKSYNEIGRAIATLMVDDLFSDVAYKARNREDLIAG 389

Query: 188 INEFLDDSIVLPPGDWERQALLPLEELRAKSEMIRRRKINALE-----RKRIVADGDKPS 242
           I+EFLD+ IVLPPG+W+    + +E  +      +R+ + +L         +   G  P 
Sbjct: 390 IDEFLDEVIVLPPGEWDPN--IRIEPPKKVPSADKRKSVFSLAELGQMNGSVGGGGGAPG 447

Query: 243 DEKKALLAAEAGG-----------------MPP-EEPDDPLSRTGRLFGGVIRDMKRRYP 284
                     +GG                 MP   E  + L  TGR FGG+  D+KR+ P
Sbjct: 448 GGNGGGGGGGSGGGAGSGGAGGTSSGDDGEMPAMHEIGEELIWTGRFFGGLCLDIKRKLP 507

Query: 285 FYVSDFVDALNGQCVAATIFMYFAAVSSAITFGGLLAEKTYGKIGISETLSSGYVRSAVE 344
           ++ SDF D  + Q ++A +F+Y   +++AITFGGLL + T    G+ E+           
Sbjct: 508 WFPSDFYDGFHIQSISAILFIYLGCITNAITFGGLLGDATDNYQGVMESF---------- 557

Query: 345 GDLQVFTSAGGVLFALVAGQPMMITGATGPLLLLDESLANFCHSYGFDFLAARMYCGLWM 404
               + T+  G LF L +GQP++I  +TGP+L+ ++ L +F    G D++  R++ GL  
Sbjct: 558 ----LGTAMAGSLFCLFSGQPLIILSSTGPILIFEKLLFDFSKGNGLDYMEFRLWIGLHS 613

Query: 405 IVIALCVASVEGSVAVKKITRFTEDXXXXXXXXXXXXEPITSTIAVYRANPLGIDYCQFR 464
            V  L + + + S  +K ITRFTE+            + I   I  ++  P+ +D+    
Sbjct: 614 AVQCLILVATDASFIIKYITRFTEEGFSTLISFIFIYDAIKKMIGAFKYYPINMDFKPNF 673

Query: 465 EVALSNSTVQPLLNSTSVGNSSV-VAPAPPVSRLPPQPNTALFCTMLTLATFVLAYYLRI 523
                   V P   +T+V N+S  +AP    S       TAL  ++L+     L+Y  R+
Sbjct: 674 ITTYKCECVAPDTVNTTVFNASAPLAPDTNASLYNLLNLTALDWSLLSKKE-CLSYGGRL 732

Query: 524 FRNG-KFLGRSSATSRVQVTGRDGI---------------QARRALGDFGVPIAIVLMVG 567
             N  KF+   +  S +   G   +               + R  + DF +  +I++  G
Sbjct: 733 LGNSCKFIPDLALMSFILFFGTYSMTLTLKKFKFSRYFPTKVRALVADFSIVFSILMFCG 792

Query: 568 ISCLVPVKTETLVVPAGLNPTTV-RSWFV-PLNPGLETIXXXXXXXXXXXXXXVYIIVFM 625
           I     ++T  L VP+ + PT   R WFV P       +              V I++FM
Sbjct: 793 IDACFGLETPKLHVPSVIKPTRPDRGWFVAPFGKNPWWV----YPASILPALLVTILIFM 848

Query: 626 ETHIAELIIAKPERRLKKGSGFHMDIVIMSFVNALCGMFGAPWQCVATVRSVSHVSALTI 685
           +  I  +I+ + E +LKK +G+H+D+  +  + ALC   G PW   ATV S++H+ +L +
Sbjct: 849 DQQITAVIVNRKENKLKKAAGYHLDLFWVGILMALCSFMGLPWYVAATVISIAHIDSLKM 908

Query: 686 MSTTHAPGDKPHIVEVKEQRLTGLLVAVMVGISVLASGWLCLVPMAVL 733
            + T APG++P  + V+EQR+TG++V ++ GISV  +  L ++ + ++
Sbjct: 909 ETETSAPGEQPQFLGVREQRVTGIIVFILTGISVFLAPILKILGLIIV 956


>AF157492-1|AAF80343.1|  995|Homo sapiens sodium bicarbonate
           cotransporter NBC1 protein.
          Length = 995

 Score =  303 bits (744), Expect = 2e-81
 Identities = 198/573 (34%), Positives = 295/573 (51%), Gaps = 50/573 (8%)

Query: 90  DSILKRIPDDAEATTVLVGAVGFLDQPTIAFVRLAEGIYMPSITEVPVPVRFMFILLGPG 149
           +  +K++P DAEA+ VLVG V FLD P IAFVRL + + + ++TEVPVP RF+FILLGP 
Sbjct: 272 NKFMKKLPRDAEASNVLVGEVDFLDTPFIAFVRLQQAVMLGALTEVPVPTRFLFILLGPK 331

Query: 150 GADLDYHEVGRSISTLMSNPAFHSIAYKADDRRELLSAINEFLDDSIVLPPGDWERQALL 209
           G    YHE+GR+I+TLMS+  FH IAYKA DR +L++ I+EFLD+ IVLPPG+W+    +
Sbjct: 332 GKAKSYHEIGRAIATLMSDEVFHDIAYKAKDRHDLIAGIDEFLDEVIVLPPGEWD--PAI 389

Query: 210 PLEELRAKSEMIRRRKINALERKRIVADGDKPSDEKKALLAAEAGGMPPEEPDDPLSRTG 269
            +E  ++     +R+ + +   + +  +GD P D          GG       + L RTG
Sbjct: 390 RIEPPKSLPSSDKRKNMYS-GGENVQMNGDTPHD------GGHGGG--GHGDCEELQRTG 440

Query: 270 RLFGGVIRDMKRRYPFYVSDFVDALNGQCVAATIFMYFAAVSSAITFGGLLAEKTYGKIG 329
           R  GG+I+D+KR+ PF+ SDF DALN Q ++A +F+Y A V++AITFGGLL + T    G
Sbjct: 441 RFCGGLIKDIKRKAPFFASDFYDALNIQALSAILFIYLATVTNAITFGGLLGDATDNMQG 500

Query: 330 ISETLSSGYVRSAVEGDLQVFTSAGGVLFALVAGQPMMITGATGPLLLLDESLANFCHSY 389
           + E+               + T+  G +F L AGQP+ I  +TGP+L+ +  L NF    
Sbjct: 501 VLESF--------------LGTAVSGAIFCLFAGQPLTILSSTGPVLVFERLLFNFSKDN 546

Query: 390 GFDFLAARMYCGLWMIVIALCVASVEGSVAVKKITRFTEDXXXXXXXXXXXXEPITSTIA 449
            FD+L  R++ GLW   + L + + + S  V+  TRFTE+            +     I 
Sbjct: 547 NFDYLEFRLWIGLWSAFLCLILVATDASFLVQYFTRFTEEGFSSLISFIFIYDAFKKMIK 606

Query: 450 VYRANPLGIDYCQFREVALSNSTVQPLLNSTSVGNSSVVAP--APPVSRLPPQPNTALFC 507
           +    P+  ++        S + V P   + S+ N + +AP   P +S      NT    
Sbjct: 607 LADYYPINSNFKVGYNTLFSCTCVPPDPANISISNDTTLAPEYLPTMSSTDMYHNTTFDW 666

Query: 508 TMLTL--------------ATFVLAYYLRIFRNGKFLG---RSSATSRVQVTGRDGIQAR 550
             L+                 FV    L  F    FLG    S A  + + +      AR
Sbjct: 667 AFLSKKECSKYGGNLVGNNCNFVPDITLMSFI--LFLGTYTSSMALKKFKTSPYFPTTAR 724

Query: 551 RALGDFGVPIAIVLMVGISCLVPVKTETLVVPAGLNPTTV-RSWFVPLNPGLETIXXXXX 609
           + + DF + ++I++   I  LV V T  L+VP+   PT+  R WFVP  P  E       
Sbjct: 725 KLISDFAIILSILIFCVIDALVGVDTPKLIVPSEFKPTSPNRGWFVP--PFGEN-PWWVC 781

Query: 610 XXXXXXXXXVYIIVFMETHIAELIIAKPERRLK 642
                    V I++FM+  I  +I+ + E +LK
Sbjct: 782 LAAAIPALLVTILIFMDQQITAVIVNRKEHKLK 814



 Score =  102 bits (245), Expect = 5e-21
 Identities = 47/120 (39%), Positives = 76/120 (63%)

Query: 725 LCLVPMAVLFGVFLYMGISALGGIQFWDRCILLLKPVKHHPQLPYVRRVPTLKMHMYTLI 784
           L  +PM VL+GVFLYMG+++L G+QF DR  LLL P+KH P   Y+R VP  ++H++T +
Sbjct: 813 LKFIPMPVLYGVFLYMGVASLNGVQFMDRLKLLLMPLKHQPDFIYLRHVPLRRVHLFTFL 872

Query: 785 QVGGVVVLYAVKSSRFSLALPFFLVLMVPLRMSLVYIFTPLQLRALDGAQKDIDKDDEPD 844
           QV  + +L+ +KS+  ++  P  ++ +V +R  + Y+F+   L  LD    + DK  + D
Sbjct: 873 QVLCLALLWILKSTVAAIIFPVMILALVAVRKGMDYLFSQHDLSFLDDVIPEKDKKKKED 932


>AC073263-6|AAX93062.1|  714|Homo sapiens unknown protein.
          Length = 714

 Score =  299 bits (733), Expect = 3e-80
 Identities = 191/628 (30%), Positives = 320/628 (50%), Gaps = 55/628 (8%)

Query: 250 AAEAGGMPP-EEPDDPLSRTGRLFGGVIRDMKRRYPFYVSDFVDALNGQCVAATIFMYFA 308
           + + G MP   E  + L  TGR FGG+  D+KR+ P++ SDF D  + Q ++A +F+Y  
Sbjct: 49  SGDDGEMPAMHEIGEELIWTGRFFGGLCLDIKRKLPWFPSDFYDGFHIQSISAILFIYLG 108

Query: 309 AVSSAITFGGLLAEKTYGKIGISETLSSGYVRSAVEGDLQVFTSAGGVLFALVAGQPMMI 368
            +++AITFGGLL + T    G+ E+                 T+  G LF L +GQP++I
Sbjct: 109 CITNAITFGGLLGDATDNYQGVMESFLG--------------TAMAGSLFCLFSGQPLII 154

Query: 369 TGATGPLLLLDESLANFCHSYGFDFLAARMYCGLWMIVIALCVASVEGSVAVKKITRFTE 428
             +TGP+L+ ++ L +F    G D++  R++ GL   V  L + + + S  +K ITRFTE
Sbjct: 155 LSSTGPILIFEKLLFDFSKGNGLDYMEFRLWIGLHSAVQCLILVATDASFIIKYITRFTE 214

Query: 429 DXXXXXXXXXXXXEPITSTIAVYRANPLGIDYCQFREVALSNSTVQPLLNSTSVGNSSV- 487
           +            + I   I  ++  P+ +D+            V P   +T+V N+S  
Sbjct: 215 EGFSTLISFIFIYDAIKKMIGAFKYYPINMDFKPNFITTYKCECVAPDTVNTTVFNASAP 274

Query: 488 VAPAPPVSRLPPQPNTALFCTMLTLATFVLAYYLRIFRNG-KFLGRSSATSRVQVTGRDG 546
           +AP    S       TAL  ++L+     L+Y  R+  N  KF+   +  S +   G   
Sbjct: 275 LAPDTNASLYNLLNLTALDWSLLSKKE-CLSYGGRLLGNSCKFIPDLALMSFILFFGTYS 333

Query: 547 I---------------QARRALGDFGVPIAIVLMVGISCLVPVKTETLVVPAGLNPTTV- 590
           +               + R  + DF +  +I++  GI     ++T  L VP+ + PT   
Sbjct: 334 MTLTLKKFKFSRYFPTKVRALVADFSIVFSILMFCGIDACFGLETPKLHVPSVIKPTRPD 393

Query: 591 RSWFV-PLNPGLETIXXXXXXXXXXXXXXVYIIVFMETHIAELIIAKPERRLKKGSGFHM 649
           R WFV P       +              V I++FM+  I  +I+ + E +LKK +G+H+
Sbjct: 394 RGWFVAPFGKNPWWVYPASILPALL----VTILIFMDQQITAVIVNRKENKLKKAAGYHL 449

Query: 650 DIVIMSFVNALCGMFGAPWQCVATVRSVSHVSALTIMSTTHAPGDKPHIVEVKEQRLTGL 709
           D+  +  + ALC   G PW   ATV S++H+ +L + + T APG++P  + V+EQR+TG+
Sbjct: 450 DLFWVGILMALCSFMGLPWYVAATVISIAHIDSLKMETETSAPGEQPQFLGVREQRVTGI 509

Query: 710 LVAVMVGISVLASGWLCLVPMAVLFGVFLYMGISALGGIQ----------------FWDR 753
           +V ++ GISV  +  L  +P+ VL+GVFLYMG+++L GIQ                FW+R
Sbjct: 510 IVFILTGISVFLAPILKCIPLPVLYGVFLYMGVASLNGIQMGTGGSEFKIQKKLTPFWER 569

Query: 754 CILLLKPVKHHPQLPYVRRVPTLKMHMYTLIQVGGVVVLYAVKSSRFSLALPFFLVLMVP 813
           C L L P KH P   ++R VP  ++H++TL+Q+  + VL+ +KS+  ++  P  ++ ++ 
Sbjct: 570 CKLFLMPAKHQPDHAFLRHVPLRRIHLFTLVQILCLAVLWILKSTVAAIIFPVMILGLII 629

Query: 814 LRMSLVYIFTPLQLRALDGAQKDIDKDD 841
           +R  L +IF+   L  +D    + +K +
Sbjct: 630 VRRLLDFIFSQHDLAWIDNILPEKEKKE 657


>BC030977-1|AAH30977.1|  646|Homo sapiens SLC4A4 protein protein.
          Length = 646

 Score =  273 bits (669), Expect = 2e-72
 Identities = 144/340 (42%), Positives = 209/340 (61%), Gaps = 25/340 (7%)

Query: 90  DSILKRIPDDAEATTVLVGAVGFLDQPTIAFVRLAEGIYMPSITEVPVPVRFMFILLGPG 149
           +  +K++P DAEA+ VLVG V FLD P IAFVRL + + + ++TEVPVP RF+FILLGP 
Sbjct: 228 NKFMKKLPRDAEASNVLVGEVDFLDTPFIAFVRLQQAVMLGALTEVPVPTRFLFILLGPK 287

Query: 150 GADLDYHEVGRSISTLMSNPAFHSIAYKADDRRELLSAINEFLDDSIVLPPGDWERQALL 209
           G    YHE+GR+I+TLMS+  FH IAYKA DR +L++ I+EFLD+ IVLPPG+W+    +
Sbjct: 288 GKAKSYHEIGRAIATLMSDEVFHDIAYKAKDRHDLIAGIDEFLDEVIVLPPGEWD--PAI 345

Query: 210 PLEELRAKSEMIRRRKINALERKRIVADGDKPSDEKKALLAAEAGGMPPEEPDDPLSRTG 269
            +E  ++     +R+ + +   + +  +GD P D          GG       + L RTG
Sbjct: 346 RIEPPKSLPSSDKRKNMYS-GGENVQMNGDTPHD------GGHGGG--GHGDCEELQRTG 396

Query: 270 RLFGGVIRDMKRRYPFYVSDFVDALNGQCVAATIFMYFAAVSSAITFGGLLAEKTYGKIG 329
           R  GG+I+D+KR+ PF+ SDF DALN Q ++A +F+Y A V++AITFGGLL + T    G
Sbjct: 397 RFCGGLIKDIKRKAPFFASDFYDALNIQALSAILFIYLATVTNAITFGGLLGDATDNMQG 456

Query: 330 ISETLSSGYVRSAVEGDLQVFTSAGGVLFALVAGQPMMITGATGPLLLLDESLANFCHSY 389
           + E+               + T+  G +F L AGQP+ I  +TGP+L+ +  L NF    
Sbjct: 457 VLESF--------------LGTAVSGAIFCLFAGQPLTILSSTGPVLVFERLLFNFSKDN 502

Query: 390 GFDFLAARMYCGLWMIVIALCVASVEGSVAVKKITRFTED 429
            FD+L  R++ GLW   + L + + + S  V+  TRFTE+
Sbjct: 503 NFDYLEFRLWIGLWSAFLCLILVATDASFLVQYFTRFTEE 542


>AF004813-1|AAD31379.1|  670|Homo sapiens electrogenic Na+
           bicarbonate cotransporter protein.
          Length = 670

 Score =  273 bits (669), Expect = 2e-72
 Identities = 144/340 (42%), Positives = 209/340 (61%), Gaps = 25/340 (7%)

Query: 90  DSILKRIPDDAEATTVLVGAVGFLDQPTIAFVRLAEGIYMPSITEVPVPVRFMFILLGPG 149
           +  +K++P DAEA+ VLVG V FLD P IAFVRL + + + ++TEVPVP RF+FILLGP 
Sbjct: 252 NKFMKKLPRDAEASNVLVGEVDFLDTPFIAFVRLQQAVMLGALTEVPVPTRFLFILLGPK 311

Query: 150 GADLDYHEVGRSISTLMSNPAFHSIAYKADDRRELLSAINEFLDDSIVLPPGDWERQALL 209
           G    YHE+GR+I+TLMS+  FH IAYKA DR +L++ I+EFLD+ IVLPPG+W+    +
Sbjct: 312 GKAKSYHEIGRAIATLMSDEVFHDIAYKAKDRHDLIAGIDEFLDEVIVLPPGEWD--PAI 369

Query: 210 PLEELRAKSEMIRRRKINALERKRIVADGDKPSDEKKALLAAEAGGMPPEEPDDPLSRTG 269
            +E  ++     +R+ + +   + +  +GD P D          GG       + L RTG
Sbjct: 370 RIEPPKSLPSSDKRKNMYS-GGENVQMNGDTPHD------GGHGGG--GHGDCEELQRTG 420

Query: 270 RLFGGVIRDMKRRYPFYVSDFVDALNGQCVAATIFMYFAAVSSAITFGGLLAEKTYGKIG 329
           R  GG+I+D+KR+ PF+ SDF DALN Q ++A +F+Y A V++AITFGGLL + T    G
Sbjct: 421 RFCGGLIKDIKRKAPFFASDFYDALNIQALSAILFIYLATVTNAITFGGLLGDATDNMQG 480

Query: 330 ISETLSSGYVRSAVEGDLQVFTSAGGVLFALVAGQPMMITGATGPLLLLDESLANFCHSY 389
           + E+               + T+  G +F L AGQP+ I  +TGP+L+ +  L NF    
Sbjct: 481 VLESF--------------LGTAVSGAIFCLFAGQPLTILSSTGPVLVFERLLFNFSKDN 526

Query: 390 GFDFLAARMYCGLWMIVIALCVASVEGSVAVKKITRFTED 429
            FD+L  R++ GLW   + L + + + S  V+  TRFTE+
Sbjct: 527 NFDYLEFRLWIGLWSAFLCLILVATDASFLVQYFTRFTEE 566


>AF089726-1|AAG16773.1| 1090|Homo sapiens sodium bicarbonate
           cotransporter 2b protein.
          Length = 1090

 Score =  270 bits (663), Expect = 1e-71
 Identities = 148/339 (43%), Positives = 206/339 (60%), Gaps = 30/339 (8%)

Query: 91  SILKRIPDDAEATTVLVGAVGFLDQPTIAFVRLAEGIYMPSITEVPVPVRFMFILLGPGG 150
           + +++IP  AEA+ VLVG V FL++P IAFVRLA  + +  +TEVPVP RF+F+LLGP G
Sbjct: 293 NFMRKIPTGAEASNVLVGEVDFLERPIIAFVRLAPAVLLTGLTEVPVPTRFLFLLLGPAG 352

Query: 151 ADLDYHEVGRSISTLMSNPAFHSIAYKADDRRELLSAINEFLDDSIVLPPGDWERQALLP 210
               YHE+GRSI+TLM++  FH +AYKA DR +LLS I+EFLD   VLPPG+W+    + 
Sbjct: 353 KAPQYHEIGRSIATLMTDEIFHDVAYKAKDRNDLLSGIDEFLDQVTVLPPGEWDPS--IR 410

Query: 211 LEELRAKSEMIRRRKINALERKRIVADGDKPSDEKKALLAAEAGGMPPEEPDDPLSRTGR 270
           +E  ++      +RKI           G+ P +      AA   G  PE     L RTGR
Sbjct: 411 IEPPKSVPSQ-EKRKIPVFHNGSTPTLGETPKE------AAHHAG--PE-----LQRTGR 456

Query: 271 LFGGVIRDMKRRYPFYVSDFVDALNGQCVAATIFMYFAAVSSAITFGGLLAEKTYGKIGI 330
           LFGG+I D+KR+ PF++SDF DAL+ QC+A+ +F+Y A +S  ITFGGLL E T G+I  
Sbjct: 457 LFGGLILDIKRKAPFFLSDFKDALSLQCLASILFLYCACMSPVITFGGLLGEATEGRISA 516

Query: 331 SETLSSGYVRSAVEGDLQVFTSAGGVLFALVAGQPMMITGATGPLLLLDESLANFCHSYG 390
            E+L                 S  G+ ++L AGQP+ I G+TGP+L+ ++ L  FC  Y 
Sbjct: 517 IESLFG--------------ASLTGIAYSLFAGQPLTILGSTGPVLVFEKILYKFCRDYQ 562

Query: 391 FDFLAARMYCGLWMIVIALCVASVEGSVAVKKITRFTED 429
             +L+ R   GLW   + + + + + S  V  ITRFTE+
Sbjct: 563 LSYLSLRTSIGLWTSFLCIVLVATDASSLVCYITRFTEE 601



 Score =  214 bits (523), Expect = 1e-54
 Identities = 121/351 (34%), Positives = 194/351 (55%), Gaps = 25/351 (7%)

Query: 498  PPQPNTALFCTMLTLATFVLAYYLRIFRNGKFLGRSSATSRVQVTGRDGIQARRALGDFG 557
            P  P+   +C +L   TF L+ +L+ F+  ++                  + R  + DF 
Sbjct: 695  PYIPDVLFWCVILFFTTFFLSSFLKQFKTKRYFPT---------------KVRSTISDFA 739

Query: 558  VPIAIVLMVGISCLVPVKTETLVVPAGLNPT-TVRSWFV-PL--NPGLETIXXXXXXXXX 613
            V + IV+MV I  LV V +  L VP    PT   R W + PL  NP    +         
Sbjct: 740  VFLTIVIMVTIDYLVGVPSPKLHVPEKFEPTHPERGWIISPLGDNPWWTLLIAAIPALLC 799

Query: 614  XXXXXVYIIVFMETHIAELIIAKPERRLKKGSGFHMDIVIMSFVNALCGMFGAPWQCVAT 673
                   I++FM+  I  +II + E +LKKG+G+H+D++++  +  +C + G PW   AT
Sbjct: 800  T------ILIFMDQQITAVIINRKEHKLKKGAGYHLDLLMVGVMLGVCSVMGLPWFVAAT 853

Query: 674  VRSVSHVSALTIMSTTHAPGDKPHIVEVKEQRLTGLLVAVMVGISVLASGWLCLVPMAVL 733
            V S+SHV++L + S   APG++P  + ++EQR+TGL++ +++G+SV  +  L  +PM VL
Sbjct: 854  VLSISHVNSLKVESECSAPGEQPKFLGIREQRVTGLMIFILMGLSVFMTSVLKFIPMPVL 913

Query: 734  FGVFLYMGISALGGIQFWDRCILLLKPVKHHPQLPYVRRVPTLKMHMYTLIQVGGVVVLY 793
            +GVFLYMG+S+L GIQ +DR  L   P KH P L Y+R VP  K+H++T+IQ+  +V+L+
Sbjct: 914  YGVFLYMGVSSLKGIQLFDRIKLFGMPAKHQPDLIYLRYVPLWKVHIFTVIQLTCLVLLW 973

Query: 794  AVKSSRFSLALPFFLVLMVPLRMSLVYIFTPLQLRALDGAQKDIDKDDEPD 844
             +K S  ++  P  ++ +V +R  +   FT  +L  LD    +  K  E D
Sbjct: 974  VIKVSAAAVVFPMMVLALVFVRKLMDLCFTKRELSWLDDLMPESKKKKEDD 1024


>AF047033-1|AAD38322.1| 1214|Homo sapiens sodium bicarbonate
           cotransporter 3 protein.
          Length = 1214

 Score =  270 bits (663), Expect = 1e-71
 Identities = 148/339 (43%), Positives = 206/339 (60%), Gaps = 30/339 (8%)

Query: 91  SILKRIPDDAEATTVLVGAVGFLDQPTIAFVRLAEGIYMPSITEVPVPVRFMFILLGPGG 150
           + +++IP  AEA+ VLVG V FL++P IAFVRLA  + +  +TEVPVP RF+F+LLGP G
Sbjct: 417 NFMRKIPTGAEASNVLVGEVDFLERPIIAFVRLAPAVLLTGLTEVPVPTRFLFLLLGPAG 476

Query: 151 ADLDYHEVGRSISTLMSNPAFHSIAYKADDRRELLSAINEFLDDSIVLPPGDWERQALLP 210
               YHE+GRSI+TLM++  FH +AYKA DR +LLS I+EFLD   VLPPG+W+    + 
Sbjct: 477 KAPQYHEIGRSIATLMTDEIFHDVAYKAKDRNDLLSGIDEFLDQVTVLPPGEWDPS--IR 534

Query: 211 LEELRAKSEMIRRRKINALERKRIVADGDKPSDEKKALLAAEAGGMPPEEPDDPLSRTGR 270
           +E  ++      +RKI           G+ P +      AA   G  PE     L RTGR
Sbjct: 535 IEPPKSVPSQ-EKRKIPVFHNGSTPTLGETPKE------AAHHAG--PE-----LQRTGR 580

Query: 271 LFGGVIRDMKRRYPFYVSDFVDALNGQCVAATIFMYFAAVSSAITFGGLLAEKTYGKIGI 330
           LFGG+I D+KR+ PF++SDF DAL+ QC+A+ +F+Y A +S  ITFGGLL E T G+I  
Sbjct: 581 LFGGLILDIKRKAPFFLSDFKDALSLQCLASILFLYCACMSPVITFGGLLGEATEGRISA 640

Query: 331 SETLSSGYVRSAVEGDLQVFTSAGGVLFALVAGQPMMITGATGPLLLLDESLANFCHSYG 390
            E+L                 S  G+ ++L AGQP+ I G+TGP+L+ ++ L  FC  Y 
Sbjct: 641 IESLFG--------------ASLTGIAYSLFAGQPLTILGSTGPVLVFEKILYKFCRDYQ 686

Query: 391 FDFLAARMYCGLWMIVIALCVASVEGSVAVKKITRFTED 429
             +L+ R   GLW   + + + + + S  V  ITRFTE+
Sbjct: 687 LSYLSLRTSIGLWTSFLCIVLVATDASSLVCYITRFTEE 725



 Score =  214 bits (523), Expect = 1e-54
 Identities = 121/351 (34%), Positives = 194/351 (55%), Gaps = 25/351 (7%)

Query: 498  PPQPNTALFCTMLTLATFVLAYYLRIFRNGKFLGRSSATSRVQVTGRDGIQARRALGDFG 557
            P  P+   +C +L   TF L+ +L+ F+  ++                  + R  + DF 
Sbjct: 819  PYIPDVLFWCVILFFTTFFLSSFLKQFKTKRYFPT---------------KVRSTISDFA 863

Query: 558  VPIAIVLMVGISCLVPVKTETLVVPAGLNPT-TVRSWFV-PL--NPGLETIXXXXXXXXX 613
            V + IV+MV I  LV V +  L VP    PT   R W + PL  NP    +         
Sbjct: 864  VFLTIVIMVTIDYLVGVPSPKLHVPEKFEPTHPERGWIISPLGDNPWWTLLIAAIPALLC 923

Query: 614  XXXXXVYIIVFMETHIAELIIAKPERRLKKGSGFHMDIVIMSFVNALCGMFGAPWQCVAT 673
                   I++FM+  I  +II + E +LKKG+G+H+D++++  +  +C + G PW   AT
Sbjct: 924  T------ILIFMDQQITAVIINRKEHKLKKGAGYHLDLLMVGVMLGVCSVMGLPWFVAAT 977

Query: 674  VRSVSHVSALTIMSTTHAPGDKPHIVEVKEQRLTGLLVAVMVGISVLASGWLCLVPMAVL 733
            V S+SHV++L + S   APG++P  + ++EQR+TGL++ +++G+SV  +  L  +PM VL
Sbjct: 978  VLSISHVNSLKVESECSAPGEQPKFLGIREQRVTGLMIFILMGLSVFMTSVLKFIPMPVL 1037

Query: 734  FGVFLYMGISALGGIQFWDRCILLLKPVKHHPQLPYVRRVPTLKMHMYTLIQVGGVVVLY 793
            +GVFLYMG+S+L GIQ +DR  L   P KH P L Y+R VP  K+H++T+IQ+  +V+L+
Sbjct: 1038 YGVFLYMGVSSLKGIQLFDRIKLFGMPAKHQPDLIYLRYVPLWKVHIFTVIQLTCLVLLW 1097

Query: 794  AVKSSRFSLALPFFLVLMVPLRMSLVYIFTPLQLRALDGAQKDIDKDDEPD 844
             +K S  ++  P  ++ +V +R  +   FT  +L  LD    +  K  E D
Sbjct: 1098 VIKVSAAAVVFPMMVLALVFVRKLMDLCFTKRELSWLDDLMPESKKKKEDD 1148


>AB012130-1|BAA25898.1| 1018|Homo sapiens sodium bicarbonate
           cotransporter2 protein.
          Length = 1018

 Score =  270 bits (663), Expect = 1e-71
 Identities = 148/339 (43%), Positives = 206/339 (60%), Gaps = 30/339 (8%)

Query: 91  SILKRIPDDAEATTVLVGAVGFLDQPTIAFVRLAEGIYMPSITEVPVPVRFMFILLGPGG 150
           + +++IP  AEA+ VLVG V FL++P IAFVRLA  + +  +TEVPVP RF+F+LLGP G
Sbjct: 203 NFMRKIPTGAEASNVLVGEVDFLERPIIAFVRLAPAVLLTGLTEVPVPTRFLFLLLGPAG 262

Query: 151 ADLDYHEVGRSISTLMSNPAFHSIAYKADDRRELLSAINEFLDDSIVLPPGDWERQALLP 210
               YHE+GRSI+TLM++  FH +AYKA DR +LLS I+EFLD   VLPPG+W+    + 
Sbjct: 263 KAPQYHEIGRSIATLMTDEIFHDVAYKAKDRNDLLSGIDEFLDQVTVLPPGEWDPS--IR 320

Query: 211 LEELRAKSEMIRRRKINALERKRIVADGDKPSDEKKALLAAEAGGMPPEEPDDPLSRTGR 270
           +E  ++      +RKI           G+ P +      AA   G  PE     L RTGR
Sbjct: 321 IEPPKSVPSQ-EKRKIPVFHNGSTPTLGETPKE------AAHHAG--PE-----LQRTGR 366

Query: 271 LFGGVIRDMKRRYPFYVSDFVDALNGQCVAATIFMYFAAVSSAITFGGLLAEKTYGKIGI 330
           LFGG+I D+KR+ PF++SDF DAL+ QC+A+ +F+Y A +S  ITFGGLL E T G+I  
Sbjct: 367 LFGGLILDIKRKAPFFLSDFKDALSLQCLASILFLYCACMSPVITFGGLLGEATEGRISA 426

Query: 331 SETLSSGYVRSAVEGDLQVFTSAGGVLFALVAGQPMMITGATGPLLLLDESLANFCHSYG 390
            E+L                 S  G+ ++L AGQP+ I G+TGP+L+ ++ L  FC  Y 
Sbjct: 427 IESLFG--------------ASLTGIAYSLFAGQPLTILGSTGPVLVFEKILYKFCRDYQ 472

Query: 391 FDFLAARMYCGLWMIVIALCVASVEGSVAVKKITRFTED 429
             +L+ R   GLW   + + + + + S  V  ITRFTE+
Sbjct: 473 LSYLSLRTSIGLWTSFLCIVLVATDASSLVCYITRFTEE 511



 Score =  214 bits (523), Expect = 1e-54
 Identities = 121/351 (34%), Positives = 194/351 (55%), Gaps = 25/351 (7%)

Query: 498 PPQPNTALFCTMLTLATFVLAYYLRIFRNGKFLGRSSATSRVQVTGRDGIQARRALGDFG 557
           P  P+   +C +L   TF L+ +L+ F+  ++                  + R  + DF 
Sbjct: 605 PYIPDVLFWCVILFFTTFFLSSFLKQFKTKRYFPT---------------KVRSTISDFA 649

Query: 558 VPIAIVLMVGISCLVPVKTETLVVPAGLNPT-TVRSWFV-PL--NPGLETIXXXXXXXXX 613
           V + IV+MV I  LV V +  L VP    PT   R W + PL  NP    +         
Sbjct: 650 VFLTIVIMVTIDYLVGVPSPKLHVPEKFEPTHPERGWIISPLGDNPWWTLLIAAIPALLC 709

Query: 614 XXXXXVYIIVFMETHIAELIIAKPERRLKKGSGFHMDIVIMSFVNALCGMFGAPWQCVAT 673
                  I++FM+  I  +II + E +LKKG+G+H+D++++  +  +C + G PW   AT
Sbjct: 710 T------ILIFMDQQITAVIINRKEHKLKKGAGYHLDLLMVGVMLGVCSVMGLPWFVAAT 763

Query: 674 VRSVSHVSALTIMSTTHAPGDKPHIVEVKEQRLTGLLVAVMVGISVLASGWLCLVPMAVL 733
           V S+SHV++L + S   APG++P  + ++EQR+TGL++ +++G+SV  +  L  +PM VL
Sbjct: 764 VLSISHVNSLKVESECSAPGEQPKFLGIREQRVTGLMIFILMGLSVFMTSVLKFIPMPVL 823

Query: 734 FGVFLYMGISALGGIQFWDRCILLLKPVKHHPQLPYVRRVPTLKMHMYTLIQVGGVVVLY 793
           +GVFLYMG+S+L GIQ +DR  L   P KH P L Y+R VP  K+H++T+IQ+  +V+L+
Sbjct: 824 YGVFLYMGVSSLKGIQLFDRIKLFGMPAKHQPDLIYLRYVPLWKVHIFTVIQLTCLVLLW 883

Query: 794 AVKSSRFSLALPFFLVLMVPLRMSLVYIFTPLQLRALDGAQKDIDKDDEPD 844
            +K S  ++  P  ++ +V +R  +   FT  +L  LD    +  K  E D
Sbjct: 884 VIKVSAAAVVFPMMVLALVFVRKLMDLCFTKRELSWLDDLMPESKKKKEDD 934


>AF053755-1|AAF21720.1| 1000|Homo sapiens bicarbonate transporter
           protein.
          Length = 1000

 Score =  268 bits (656), Expect = 7e-71
 Identities = 147/339 (43%), Positives = 205/339 (60%), Gaps = 30/339 (8%)

Query: 91  SILKRIPDDAEATTVLVGAVGFLDQPTIAFVRLAEGIYMPSITEVPVPVRFMFILLGPGG 150
           + +++IP  AEA+ VLVG V FL++P IAFVRLA  + +  +TEVPVP RF+F+LLGP G
Sbjct: 203 NFMRKIPTGAEASNVLVGEVDFLERPIIAFVRLAPAVLLTGLTEVPVPTRFLFLLLGPAG 262

Query: 151 ADLDYHEVGRSISTLMSNPAFHSIAYKADDRRELLSAINEFLDDSIVLPPGDWERQALLP 210
               YHE+GRSI+TLM++  FH +AYKA DR +LLS I+EFLD   VLPPG+W+    + 
Sbjct: 263 KAPQYHEIGRSIATLMTDEIFHDVAYKAKDRNDLLSGIDEFLDQVTVLPPGEWDPS--IR 320

Query: 211 LEELRAKSEMIRRRKINALERKRIVADGDKPSDEKKALLAAEAGGMPPEEPDDPLSRTGR 270
           +E  ++      +RKI           G+ P +      AA   G  PE     L RTGR
Sbjct: 321 IEPPKSVPSQ-EKRKIPVFHNGSTPTLGETPKE------AAHHAG--PE-----LQRTGR 366

Query: 271 LFGGVIRDMKRRYPFYVSDFVDALNGQCVAATIFMYFAAVSSAITFGGLLAEKTYGKIGI 330
           LFGG+I D+KR+ PF++SDF DAL+ QC+A+ +F+Y A +S  ITFGGLL E T G+I  
Sbjct: 367 LFGGLILDIKRKAPFFLSDFKDALSLQCLASILFLYCACMSPVITFGGLLGEATEGRISA 426

Query: 331 SETLSSGYVRSAVEGDLQVFTSAGGVLFALVAGQPMMITGATGPLLLLDESLANFCHSYG 390
            E+L                 S  G+ ++L AGQP+ I G+TGP+L+ ++ L  FC  Y 
Sbjct: 427 IESLFG--------------ASLTGIAYSLFAGQPLTILGSTGPVLVFEKILYKFCRDYQ 472

Query: 391 FDFLAARMYCGLWMIVIALCVASVEGSVAVKKITRFTED 429
             +L+ R    LW   + + + + + S  V  ITRFTE+
Sbjct: 473 LSYLSLRTSIXLWTSFLCIVLVATDASSLVCYITRFTEE 511



 Score =  214 bits (523), Expect = 1e-54
 Identities = 121/351 (34%), Positives = 194/351 (55%), Gaps = 25/351 (7%)

Query: 498 PPQPNTALFCTMLTLATFVLAYYLRIFRNGKFLGRSSATSRVQVTGRDGIQARRALGDFG 557
           P  P+   +C +L   TF L+ +L+ F+  ++                  + R  + DF 
Sbjct: 605 PYIPDVLFWCVILFFTTFFLSSFLKQFKTKRYFPT---------------KVRSTISDFA 649

Query: 558 VPIAIVLMVGISCLVPVKTETLVVPAGLNPT-TVRSWFV-PL--NPGLETIXXXXXXXXX 613
           V + IV+MV I  LV V +  L VP    PT   R W + PL  NP    +         
Sbjct: 650 VFLTIVIMVTIDYLVGVPSPKLHVPEKFEPTHPERGWIISPLGDNPWWTLLIAAIPALLC 709

Query: 614 XXXXXVYIIVFMETHIAELIIAKPERRLKKGSGFHMDIVIMSFVNALCGMFGAPWQCVAT 673
                  I++FM+  I  +II + E +LKKG+G+H+D++++  +  +C + G PW   AT
Sbjct: 710 T------ILIFMDQQITAVIINRKEHKLKKGAGYHLDLLMVGVMLGVCSVMGLPWFVAAT 763

Query: 674 VRSVSHVSALTIMSTTHAPGDKPHIVEVKEQRLTGLLVAVMVGISVLASGWLCLVPMAVL 733
           V S+SHV++L + S   APG++P  + ++EQR+TGL++ +++G+SV  +  L  +PM VL
Sbjct: 764 VLSISHVNSLKVESECSAPGEQPKFLGIREQRVTGLMIFILMGLSVFMTSVLKFIPMPVL 823

Query: 734 FGVFLYMGISALGGIQFWDRCILLLKPVKHHPQLPYVRRVPTLKMHMYTLIQVGGVVVLY 793
           +GVFLYMG+S+L GIQ +DR  L   P KH P L Y+R VP  K+H++T+IQ+  +V+L+
Sbjct: 824 YGVFLYMGVSSLKGIQLFDRIKLFGMPAKHQPDLIYLRYVPLWKVHIFTVIQLTCLVLLW 883

Query: 794 AVKSSRFSLALPFFLVLMVPLRMSLVYIFTPLQLRALDGAQKDIDKDDEPD 844
            +K S  ++  P  ++ +V +R  +   FT  +L  LD    +  K  E D
Sbjct: 884 VIKVSAAAVVFPMMVLALVFVRKLMDLCFTKRELSWLDDLMPESKKKKEDD 934


>AB209752-1|BAD92989.1|  906|Homo sapiens sodium bicarbonate
           transporter 4 isoform d variant protein.
          Length = 906

 Score =  258 bits (633), Expect = 5e-68
 Identities = 192/617 (31%), Positives = 301/617 (48%), Gaps = 69/617 (11%)

Query: 74  LAHA-SESQDELRRTHN-----DSILKRIPDDAEATTVLVGAVGFLDQPTIAFVRLAEGI 127
           L HA S S +++  T N     +  +K+IP D+EA+ VLVG V FLDQP IAFVRL +  
Sbjct: 183 LCHAQSRSMNDISLTPNTDQRKNKFMKKIPKDSEASNVLVGEVDFLDQPFIAFVRLIQSA 242

Query: 128 YMPSITEVPVPVRFMFILLGPGGADLDYHEVGRSISTLMSNPAFHSIAYKADDRRELLSA 187
            +  +TEVPVP RF+FILLGP G    Y+E+GR+I+TLM +  F  +AYKA +R +L++ 
Sbjct: 243 MLGGVTEVPVPTRFLFILLGPSGRAKSYNEIGRAIATLMVDDLFSDVAYKARNREDLIAG 302

Query: 188 INEFLDDSIVLPPGDWERQALLPLEELRAKSEMIRRRKINALE-----RKRIVADGDKPS 242
           I+EFLD+ IVLPPG+W+    + +E  +      +R+ + +L         +   G  P 
Sbjct: 303 IDEFLDEVIVLPPGEWDPN--IRIEPPKKVPSADKRKSVFSLAELGQMNGSVGGGGGAPG 360

Query: 243 DEKKALLAAEAGG-----------------MPP-EEPDDPLSRTGRLFGGVIRDMKRRYP 284
                     +GG                 MP   E  + L  TGR FGG+  D+KR+ P
Sbjct: 361 GGNGGGGGGGSGGGAGSGGAGGTSSGDDGEMPAMHEIGEELIWTGRFFGGLCLDIKRKLP 420

Query: 285 FYVSDFVDALNGQCVAATIFMYFAAVSSAITFGGLLAEKTYGKIGISETLSSGYVRSAVE 344
           ++ SDF D  + Q ++A +F+Y   +++AITFGGLL + T    G+ E+           
Sbjct: 421 WFPSDFYDGFHIQSISAILFIYLGCITNAITFGGLLGDATDNYQGVMESF---------- 470

Query: 345 GDLQVFTSAGGVLFALVAGQPMMITGATGPLLLLDESLANFCHSYGFDFLAARMYCGLWM 404
               + T+  G LF L +GQP++I  +TGP+L+ ++ L +F    G D++  R++ GL  
Sbjct: 471 ----LGTAMAGSLFCLFSGQPLIILSSTGPILIFEKLLFDFSKGNGLDYMEFRLWIGLHS 526

Query: 405 IVIALCVASVEGSVAVKKITRFTEDXXXXXXXXXXXXEPITSTIAVYRANPLGIDYCQFR 464
            V  L + + + S  +K ITRFTE+            + I   I  ++  P+ +D+    
Sbjct: 527 AVQCLILVATDASFIIKYITRFTEEGFSTLISFIFIYDAIKKMIGAFKYYPINMDFKPNF 586

Query: 465 EVALSNSTVQPLLNSTSVGNSSV-VAPAPPVSRLPPQPNTALFCTMLTLATFVLAYYLRI 523
                   V P   +T+V N+S  +AP    S       TAL  ++L+     L+Y  R+
Sbjct: 587 ITTYKCECVAPDTVNTTVFNASAPLAPDTNASLYNLLNLTALDWSLLSKKE-CLSYGGRL 645

Query: 524 FRNG-KFLGRSSATSRVQVTGRDGI---------------QARRALGDFGVPIAIVLMVG 567
             N  KF+   +  S +   G   +               + R  + DF +  +I++  G
Sbjct: 646 LGNSCKFIPDLALMSFILFFGTYSMTLTLKKFKFSRYFPTKVRALVADFSIVFSILMFCG 705

Query: 568 ISCLVPVKTETLVVPAGLNPTTV-RSWFV-PLNPGLETIXXXXXXXXXXXXXXVYIIVFM 625
           I     ++T  L VP+ + PT   R WFV P       +              V I++FM
Sbjct: 706 IDACFGLETPKLHVPSVIKPTRPDRGWFVAPFGKNPWWV----YPASILPALLVTILIFM 761

Query: 626 ETHIAELIIAKPERRLK 642
           +  I  +I+ + E +LK
Sbjct: 762 DQQITAVIVNRKENKLK 778


>AY376402-1|AAQ83632.1| 1118|Homo sapiens solute carrier family 4
           sodium bicarbonate cotransporter-like member 10 protein.
          Length = 1118

 Score =  258 bits (631), Expect = 8e-68
 Identities = 149/397 (37%), Positives = 216/397 (54%), Gaps = 38/397 (9%)

Query: 62  SAAGLDPREVEYLAHASESQDELRRTHNDSILKRIPDDAEATTVLVGAVGFLDQPTIAFV 121
           S  G+  R  +   H  E + +L        +K+IP  AEA+ +LVG + FLD+  +AFV
Sbjct: 297 SPCGMKQRHEKGPPHQQEREVDLH------FMKKIPPGAEASNILVGELEFLDRTVVAFV 350

Query: 122 RLAEGIYMPSITEVPVPVRFMFILLGPGGADLDYHEVGRSISTLMSNPAFHSIAYKADDR 181
           RL+  + +  + EVP+P RF+FILLGP G    YHE+GRSI+TLM++  FH +AYKA DR
Sbjct: 351 RLSPAVLLQGLAEVPIPTRFLFILLGPLGKGQQYHEIGRSIATLMTDEVFHDVAYKAKDR 410

Query: 182 RELLSAINEFLDDSIVLPPGDWERQALLPLEELRAKSEMIRRRKINALERKRIVADGDKP 241
            +L+S I+EFLD   VLPPG+W+    +   +     E   +RKI A      V +G   
Sbjct: 411 NDLVSGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQE---KRKIPA------VPNGTAA 461

Query: 242 SDEKKALLAAEAGGMPPEEPDDPLSRTGRLFGGVIRDMKRRYPFYVSDFVDALNGQCVAA 301
             E +       G   PE     L RTGR+FGG+I D+KR+ P++ SDF DA + QC+A+
Sbjct: 462 HGEAE----PHGGHSGPE-----LQRTGRIFGGLILDIKRKAPYFWSDFRDAFSLQCLAS 512

Query: 302 TIFMYFAAVSSAITFGGLLAEKTYGKIGISETLSSGYVRSAVEGDLQVFTSAGGVLFALV 361
            +F+Y A +S  ITFGGLL E T G+I   E+L                 S  G+ ++L 
Sbjct: 513 FLFLYCACMSPVITFGGLLGEATEGRISAIESLFG--------------ASMTGIAYSLF 558

Query: 362 AGQPMMITGATGPLLLLDESLANFCHSYGFDFLAARMYCGLWMIVIALCVASVEGSVAVK 421
            GQP+ I G+TGP+L+ ++ L  FC  YG  +L+ R   GLW   + + + + + S  V 
Sbjct: 559 GGQPLTILGSTGPVLVFEKILFKFCKEYGLSYLSLRASIGLWTATLCIILVATDASSLVC 618

Query: 422 KITRFTEDXXXXXXXXXXXXEPITSTIAVYRANPLGI 458
            ITRFTE+            E +     +  A P+ +
Sbjct: 619 YITRFTEEAFASLICIIFIYEALEKLFELSEAYPINM 655



 Score =  206 bits (504), Expect = 2e-52
 Identities = 108/303 (35%), Positives = 174/303 (57%), Gaps = 6/303 (1%)

Query: 548  QARRALGDFGVPIAIVLMVGISCLVPVKTETLVVPAGLNPTTV-RSWFV-PLNPGLETIX 605
            + R  + DF V + I+ MV I   + + +  L VP+   PT   R WFV PL P      
Sbjct: 755  KVRSIVSDFAVFLTILCMVLIDYAIGIPSPKLQVPSVFKPTRDDRGWFVTPLGPN----P 810

Query: 606  XXXXXXXXXXXXXVYIIVFMETHIAELIIAKPERRLKKGSGFHMDIVIMSFVNALCGMFG 665
                           I++FM+  I  +II + E +LKKG G+H+D+++++ +  +C + G
Sbjct: 811  WWTVIAAIIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMVAVMLGVCSIMG 870

Query: 666  APWQCVATVRSVSHVSALTIMSTTHAPGDKPHIVEVKEQRLTGLLVAVMVGISVLASGWL 725
             PW   ATV S++HV++L + S   APG++P  + ++EQR+TGL++ +++G SV  +  L
Sbjct: 871  LPWFVAATVLSITHVNSLKLESECSAPGEQPKFLGIREQRVTGLMIFILMGSSVFMTSIL 930

Query: 726  CLVPMAVLFGVFLYMGISALGGIQFWDRCILLLKPVKHHPQLPYVRRVPTLKMHMYTLIQ 785
              +PM VL+GVFLYMG S+L GIQF+DR  L   P KH P   Y+R VP  K+H++T+IQ
Sbjct: 931  KFIPMPVLYGVFLYMGASSLKGIQFFDRIKLFWMPAKHQPDFIYLRHVPLRKVHLFTIIQ 990

Query: 786  VGGVVVLYAVKSSRFSLALPFFLVLMVPLRMSLVYIFTPLQLRALDGAQKDIDKDDEPDF 845
            +  + +L+ +K SR ++  P  ++ +V +R  +  +FT  +L  LD    +  K    D 
Sbjct: 991  MSCLGLLWIIKVSRAAIVFPMMVLALVFVRKLMDLLFTKRELSWLDDLMPESKKKKLEDA 1050

Query: 846  YEE 848
             +E
Sbjct: 1051 EKE 1053


>AB040457-1|BAB18301.1| 1088|Homo sapiens NCBE protein.
          Length = 1088

 Score =  256 bits (627), Expect = 2e-67
 Identities = 142/366 (38%), Positives = 206/366 (56%), Gaps = 32/366 (8%)

Query: 93  LKRIPDDAEATTVLVGAVGFLDQPTIAFVRLAEGIYMPSITEVPVPVRFMFILLGPGGAD 152
           +K+IP  AEA+ +L+G + FLD+  +AFVRL+  + +  + EVP+P RF+FILLGP G  
Sbjct: 292 MKKIPPGAEASNILLGELEFLDRTVVAFVRLSPAVLLQGLAEVPIPTRFLFILLGPLGKG 351

Query: 153 LDYHEVGRSISTLMSNPAFHSIAYKADDRRELLSAINEFLDDSIVLPPGDWERQALLPLE 212
             YHE+GRSI+TLM++  FH +AYKA DR +L+S I+EFLD   VLPPG+W+    +   
Sbjct: 352 QQYHEIGRSIATLMTDEVFHDVAYKAKDRNDLVSGIDEFLDQVTVLPPGEWDPSIRIEPP 411

Query: 213 ELRAKSEMIRRRKINALERKRIVADGDKPSDEKKALLAAEAGGMPPEEPDDPLSRTGRLF 272
           +     E   +RKI A      V +G     E +       G   PE     L RTGR+F
Sbjct: 412 KNVPSQE---KRKIPA------VPNGTAAHGEAE----PHGGHSGPE-----LQRTGRIF 453

Query: 273 GGVIRDMKRRYPFYVSDFVDALNGQCVAATIFMYFAAVSSAITFGGLLAEKTYGKIGISE 332
           GG+I D+KR+ P++ SDF DA + QC+A+ +F+Y A +S  ITFGGLL E T G+I   E
Sbjct: 454 GGLILDIKRKAPYFWSDFRDAFSLQCLASFLFLYCACMSPVITFGGLLGEATEGRISAIE 513

Query: 333 TLSSGYVRSAVEGDLQVFTSAGGVLFALVAGQPMMITGATGPLLLLDESLANFCHSYGFD 392
           +L                 S  G+ ++L  GQP+ I G+TGP+L+ ++ L  FC  YG  
Sbjct: 514 SLFG--------------ASMTGIAYSLFGGQPLTILGSTGPVLVFEKILFKFCKEYGLS 559

Query: 393 FLAARMYCGLWMIVIALCVASVEGSVAVKKITRFTEDXXXXXXXXXXXXEPITSTIAVYR 452
           +L+ R   GLW   + + + + + S  V  ITRFTE+            E +     +  
Sbjct: 560 YLSLRASIGLWTATLCIILVATDASSLVCYITRFTEEAFASLICIIFIYEALEKLFELSE 619

Query: 453 ANPLGI 458
           A P+ +
Sbjct: 620 AYPINM 625



 Score =  204 bits (497), Expect = 1e-51
 Identities = 106/294 (36%), Positives = 171/294 (58%), Gaps = 6/294 (2%)

Query: 548  QARRALGDFGVPIAIVLMVGISCLVPVKTETLVVPAGLNPTTV-RSWFV-PLNPGLETIX 605
            + R  + DF V + I+ MV I   + + +  L VP+   PT   R WFV PL P      
Sbjct: 725  KVRSIVSDFAVFLTILCMVLIDYAIGIPSPKLQVPSVFKPTRDDRGWFVTPLGPN----P 780

Query: 606  XXXXXXXXXXXXXVYIIVFMETHIAELIIAKPERRLKKGSGFHMDIVIMSFVNALCGMFG 665
                           I++FM+  I  +II + E +LKKG G+H+D+++++ +  +C + G
Sbjct: 781  WWTVIAAIIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMVAVMLGVCSIMG 840

Query: 666  APWQCVATVRSVSHVSALTIMSTTHAPGDKPHIVEVKEQRLTGLLVAVMVGISVLASGWL 725
             PW   ATV S++HV++L + S   APG++P  + ++EQR+TGL++ +++G SV  +  L
Sbjct: 841  LPWFVAATVLSITHVNSLKLESECSAPGEQPKFLGIREQRVTGLMIFILMGSSVFMTSIL 900

Query: 726  CLVPMAVLFGVFLYMGISALGGIQFWDRCILLLKPVKHHPQLPYVRRVPTLKMHMYTLIQ 785
              +PM VL+GVFLYMG S+L GIQF+DR  L   P KH P   Y+R VP  K+H++T+IQ
Sbjct: 901  KFIPMPVLYGVFLYMGASSLKGIQFFDRIKLFWMPAKHQPDFIYLRHVPLRKVHLFTIIQ 960

Query: 786  VGGVVVLYAVKSSRFSLALPFFLVLMVPLRMSLVYIFTPLQLRALDGAQKDIDK 839
            +  + +L+ +K SR ++  P  ++ +V +R  +  +FT  +L  LD    +  K
Sbjct: 961  MSCLGLLWIIKVSRAAIVSPMMVLSLVFVRKLMDLLFTKRELCWLDDLMPESKK 1014


>DQ996537-1|ABJ91576.1|  991|Homo sapiens sodium bicarbonate
           cotransporter protein.
          Length = 991

 Score =  252 bits (617), Expect = 4e-66
 Identities = 140/364 (38%), Positives = 204/364 (56%), Gaps = 32/364 (8%)

Query: 93  LKRIPDDAEATTVLVGAVGFLDQPTIAFVRLAEGIYMPSITEVPVPVRFMFILLGPGGAD 152
           +K+IP  AEA+ VLVG V  LD+P +AFVRL+  + +  +TEVP+P RF+FILLGP G  
Sbjct: 238 MKKIPTGAEASNVLVGEVDILDRPIVAFVRLSPAVLLSGLTEVPIPTRFLFILLGPVGKG 297

Query: 153 LDYHEVGRSISTLMSNPAFHSIAYKADDRRELLSAINEFLDDSIVLPPGDWERQALLPLE 212
             YHE+GRS++T+M++  FH +AYKA +R +LL+ I+EFLD   VLPPG+W+    +   
Sbjct: 298 QQYHEIGRSMATIMTDEIFHDVAYKAKERDDLLAGIDEFLDQVTVLPPGEWDPSIRIEPP 357

Query: 213 ELRAKSEMIRRRKINALERKRIVADGDKPSDEKKALLAAEAGGMPPEEPDDPLSRTGRLF 272
           +     E   +RK+  +    +     +P            G   PE     L RTGRLF
Sbjct: 358 KNVPSQE---KRKMPGVPNGNVCHIEQEP----------HGGHSGPE-----LQRTGRLF 399

Query: 273 GGVIRDMKRRYPFYVSDFVDALNGQCVAATIFMYFAAVSSAITFGGLLAEKTYGKIGISE 332
           GG++ D+KR+ P+Y SD+ DAL+ QC+A+ +F+Y A +S  ITFGGLL E T G+I   E
Sbjct: 400 GGLVLDIKRKAPWYWSDYRDALSLQCLASFLFLYCACMSPVITFGGLLGEATEGRISAIE 459

Query: 333 TLSSGYVRSAVEGDLQVFTSAGGVLFALVAGQPMMITGATGPLLLLDESLANFCHSYGFD 392
           +L                 S  G+ ++L AGQ + I G+TGP+L+ ++ L  FC  Y   
Sbjct: 460 SLFG--------------ASMTGIAYSLFAGQALTILGSTGPVLVFEKILFKFCKDYALS 505

Query: 393 FLAARMYCGLWMIVIALCVASVEGSVAVKKITRFTEDXXXXXXXXXXXXEPITSTIAVYR 452
           +L+ R   GLW   + + + + + S  V  ITRFTE+            E I   I +  
Sbjct: 506 YLSLRACIGLWTAFLCIVLVATDASSLVCYITRFTEEAFASLICIIFIYEAIEKLIHLAE 565

Query: 453 ANPL 456
             P+
Sbjct: 566 TYPI 569



 Score =  207 bits (506), Expect = 1e-52
 Identities = 118/354 (33%), Positives = 194/354 (54%), Gaps = 21/354 (5%)

Query: 498 PPQPNTALFCTMLTLATFVLAYYLRIFRNGKFLGRSSATSRVQVTGRDGIQARRALGDFG 557
           P  P+   +  +L   TF+L+  L+ F+  ++       +RV          R  + DF 
Sbjct: 636 PYTPDVLFWSCILFFTTFILSSTLKTFKTSRYF-----PTRV----------RSMVSDFA 680

Query: 558 VPIAIVLMVGISCLVPVKTETLVVPAGLNPTTV-RSWFV-PLNPGLETIXXXXXXXXXXX 615
           V + I  MV I  L+ V +  L VP+   PT   R W + P+ P                
Sbjct: 681 VFLTIFTMVIIDFLIGVPSPKLQVPSVFKPTRDDRGWIINPIGPN----PWWTVIAAIIP 736

Query: 616 XXXVYIIVFMETHIAELIIAKPERRLKKGSGFHMDIVIMSFVNALCGMFGAPWQCVATVR 675
                I++FM+  I  +II + E +LKKG G+H+D+++++ +  +C + G PW   ATV 
Sbjct: 737 ALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMVAIMLGVCSIMGLPWFVAATVL 796

Query: 676 SVSHVSALTIMSTTHAPGDKPHIVEVKEQRLTGLLVAVMVGISVLASGWLCLVPMAVLFG 735
           S++HV++L + S   APG++P  + ++EQR+TGL++ V++G SV  +  L  +PM VL+G
Sbjct: 797 SITHVNSLKLESECSAPGEQPKFLGIREQRVTGLMIFVLMGCSVFMTAILKFIPMPVLYG 856

Query: 736 VFLYMGISALGGIQFWDRCILLLKPVKHHPQLPYVRRVPTLKMHMYTLIQVGGVVVLYAV 795
           VFLYMG+S+L GIQF+DR  L   P KH P   Y+R VP  K+H++TLIQ+  +V+L+ +
Sbjct: 857 VFLYMGVSSLQGIQFFDRLKLFGMPAKHQPDFIYLRHVPLRKVHLFTLIQLTCLVLLWVI 916

Query: 796 KSSRFSLALPFFLVLMVPLRMSLVYIFTPLQLRALDGAQKDIDKDDEPDFYEEA 849
           K+S  ++  P  ++ +V +R  +   F+  +L  LD    +  K    D  ++A
Sbjct: 917 KASPAAIVFPMMVLALVFVRKVMDLCFSKRELSWLDDLMPESKKKKLDDAKKKA 970


>DQ996398-1|ABJ91577.1|  991|Homo sapiens sodium bicarbonate
           cotransporter protein.
          Length = 991

 Score =  252 bits (617), Expect = 4e-66
 Identities = 140/364 (38%), Positives = 204/364 (56%), Gaps = 32/364 (8%)

Query: 93  LKRIPDDAEATTVLVGAVGFLDQPTIAFVRLAEGIYMPSITEVPVPVRFMFILLGPGGAD 152
           +K+IP  AEA+ VLVG V  LD+P +AFVRL+  + +  +TEVP+P RF+FILLGP G  
Sbjct: 238 MKKIPTGAEASNVLVGEVDILDRPIVAFVRLSPAVLLSGLTEVPIPTRFLFILLGPVGKG 297

Query: 153 LDYHEVGRSISTLMSNPAFHSIAYKADDRRELLSAINEFLDDSIVLPPGDWERQALLPLE 212
             YHE+GRS++T+M++  FH +AYKA +R +LL+ I+EFLD   VLPPG+W+    +   
Sbjct: 298 QQYHEIGRSMATIMTDEIFHDVAYKAKERDDLLAGIDEFLDQVTVLPPGEWDPSIRIEPP 357

Query: 213 ELRAKSEMIRRRKINALERKRIVADGDKPSDEKKALLAAEAGGMPPEEPDDPLSRTGRLF 272
           +     E   +RK+  +    +     +P            G   PE     L RTGRLF
Sbjct: 358 KNVPSQE---KRKMPGVPNGNVCHIEQEP----------HGGHSGPE-----LQRTGRLF 399

Query: 273 GGVIRDMKRRYPFYVSDFVDALNGQCVAATIFMYFAAVSSAITFGGLLAEKTYGKIGISE 332
           GG++ D+KR+ P+Y SD+ DAL+ QC+A+ +F+Y A +S  ITFGGLL E T G+I   E
Sbjct: 400 GGLVLDIKRKAPWYWSDYRDALSLQCLASFLFLYCACMSPVITFGGLLGEATEGRISAIE 459

Query: 333 TLSSGYVRSAVEGDLQVFTSAGGVLFALVAGQPMMITGATGPLLLLDESLANFCHSYGFD 392
           +L                 S  G+ ++L AGQ + I G+TGP+L+ ++ L  FC  Y   
Sbjct: 460 SLFG--------------ASMTGIAYSLFAGQALTILGSTGPVLVFEKILFKFCKDYALS 505

Query: 393 FLAARMYCGLWMIVIALCVASVEGSVAVKKITRFTEDXXXXXXXXXXXXEPITSTIAVYR 452
           +L+ R   GLW   + + + + + S  V  ITRFTE+            E I   I +  
Sbjct: 506 YLSLRACIGLWTAFLCIVLVATDASSLVCYITRFTEEAFASLICIIFIYEAIEKLIHLAE 565

Query: 453 ANPL 456
             P+
Sbjct: 566 TYPI 569



 Score =  207 bits (506), Expect = 1e-52
 Identities = 118/354 (33%), Positives = 194/354 (54%), Gaps = 21/354 (5%)

Query: 498 PPQPNTALFCTMLTLATFVLAYYLRIFRNGKFLGRSSATSRVQVTGRDGIQARRALGDFG 557
           P  P+   +  +L   TF+L+  L+ F+  ++       +RV          R  + DF 
Sbjct: 636 PYTPDVLFWSCILFFTTFILSSTLKTFKTSRYF-----PTRV----------RSMVSDFA 680

Query: 558 VPIAIVLMVGISCLVPVKTETLVVPAGLNPTTV-RSWFV-PLNPGLETIXXXXXXXXXXX 615
           V + I  MV I  L+ V +  L VP+   PT   R W + P+ P                
Sbjct: 681 VFLTIFTMVIIDFLIGVPSPKLQVPSVFKPTRDDRGWIINPIGPN----PWWTVIAAIIP 736

Query: 616 XXXVYIIVFMETHIAELIIAKPERRLKKGSGFHMDIVIMSFVNALCGMFGAPWQCVATVR 675
                I++FM+  I  +II + E +LKKG G+H+D+++++ +  +C + G PW   ATV 
Sbjct: 737 ALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMVAIMLGVCSIMGLPWFVAATVL 796

Query: 676 SVSHVSALTIMSTTHAPGDKPHIVEVKEQRLTGLLVAVMVGISVLASGWLCLVPMAVLFG 735
           S++HV++L + S   APG++P  + ++EQR+TGL++ V++G SV  +  L  +PM VL+G
Sbjct: 797 SITHVNSLKLESECSAPGEQPKFLGIREQRVTGLMIFVLMGCSVFMTAILKFIPMPVLYG 856

Query: 736 VFLYMGISALGGIQFWDRCILLLKPVKHHPQLPYVRRVPTLKMHMYTLIQVGGVVVLYAV 795
           VFLYMG+S+L GIQF+DR  L   P KH P   Y+R VP  K+H++TLIQ+  +V+L+ +
Sbjct: 857 VFLYMGVSSLQGIQFFDRLKLFGMPAKHQPDFIYLRHVPLRKVHLFTLIQLTCLVLLWVI 916

Query: 796 KSSRFSLALPFFLVLMVPLRMSLVYIFTPLQLRALDGAQKDIDKDDEPDFYEEA 849
           K+S  ++  P  ++ +V +R  +   F+  +L  LD    +  K    D  ++A
Sbjct: 917 KASPAAIVFPMMVLALVFVRKVMDLCFSKRELSWLDDLMPESKKKKLDDAKKKA 970


>DQ975204-1|ABJ09587.1| 1040|Homo sapiens sodium-driven chloride
           bicarbonate exchanger protein.
          Length = 1040

 Score =  252 bits (617), Expect = 4e-66
 Identities = 140/364 (38%), Positives = 204/364 (56%), Gaps = 32/364 (8%)

Query: 93  LKRIPDDAEATTVLVGAVGFLDQPTIAFVRLAEGIYMPSITEVPVPVRFMFILLGPGGAD 152
           +K+IP  AEA+ VLVG V  LD+P +AFVRL+  + +  +TEVP+P RF+FILLGP G  
Sbjct: 238 MKKIPTGAEASNVLVGEVDILDRPIVAFVRLSPAVLLSGLTEVPIPTRFLFILLGPVGKG 297

Query: 153 LDYHEVGRSISTLMSNPAFHSIAYKADDRRELLSAINEFLDDSIVLPPGDWERQALLPLE 212
             YHE+GRS++T+M++  FH +AYKA +R +LL+ I+EFLD   VLPPG+W+    +   
Sbjct: 298 QQYHEIGRSMATIMTDEIFHDVAYKAKERDDLLAGIDEFLDQVTVLPPGEWDPSIRIEPP 357

Query: 213 ELRAKSEMIRRRKINALERKRIVADGDKPSDEKKALLAAEAGGMPPEEPDDPLSRTGRLF 272
           +     E   +RK+  +    +     +P            G   PE     L RTGRLF
Sbjct: 358 KNVPSQE---KRKMPGVPNGNVCHIEQEP----------HGGHSGPE-----LQRTGRLF 399

Query: 273 GGVIRDMKRRYPFYVSDFVDALNGQCVAATIFMYFAAVSSAITFGGLLAEKTYGKIGISE 332
           GG++ D+KR+ P+Y SD+ DAL+ QC+A+ +F+Y A +S  ITFGGLL E T G+I   E
Sbjct: 400 GGLVLDIKRKAPWYWSDYRDALSLQCLASFLFLYCACMSPVITFGGLLGEATEGRISAIE 459

Query: 333 TLSSGYVRSAVEGDLQVFTSAGGVLFALVAGQPMMITGATGPLLLLDESLANFCHSYGFD 392
           +L                 S  G+ ++L AGQ + I G+TGP+L+ ++ L  FC  Y   
Sbjct: 460 SLFG--------------ASMTGIAYSLFAGQALTILGSTGPVLVFEKILFKFCKDYALS 505

Query: 393 FLAARMYCGLWMIVIALCVASVEGSVAVKKITRFTEDXXXXXXXXXXXXEPITSTIAVYR 452
           +L+ R   GLW   + + + + + S  V  ITRFTE+            E I   I +  
Sbjct: 506 YLSLRACIGLWTAFLCIVLVATDASSLVCYITRFTEEAFASLICIIFIYEAIEKLIHLAE 565

Query: 453 ANPL 456
             P+
Sbjct: 566 TYPI 569



 Score =  207 bits (506), Expect = 1e-52
 Identities = 118/354 (33%), Positives = 194/354 (54%), Gaps = 21/354 (5%)

Query: 498 PPQPNTALFCTMLTLATFVLAYYLRIFRNGKFLGRSSATSRVQVTGRDGIQARRALGDFG 557
           P  P+   +  +L   TF+L+  L+ F+  ++       +RV          R  + DF 
Sbjct: 636 PYTPDVLFWSCILFFTTFILSSTLKTFKTSRYF-----PTRV----------RSMVSDFA 680

Query: 558 VPIAIVLMVGISCLVPVKTETLVVPAGLNPTTV-RSWFV-PLNPGLETIXXXXXXXXXXX 615
           V + I  MV I  L+ V +  L VP+   PT   R W + P+ P                
Sbjct: 681 VFLTIFTMVIIDFLIGVPSPKLQVPSVFKPTRDDRGWIINPIGPN----PWWTVIAAIIP 736

Query: 616 XXXVYIIVFMETHIAELIIAKPERRLKKGSGFHMDIVIMSFVNALCGMFGAPWQCVATVR 675
                I++FM+  I  +II + E +LKKG G+H+D+++++ +  +C + G PW   ATV 
Sbjct: 737 ALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMVAIMLGVCSIMGLPWFVAATVL 796

Query: 676 SVSHVSALTIMSTTHAPGDKPHIVEVKEQRLTGLLVAVMVGISVLASGWLCLVPMAVLFG 735
           S++HV++L + S   APG++P  + ++EQR+TGL++ V++G SV  +  L  +PM VL+G
Sbjct: 797 SITHVNSLKLESECSAPGEQPKFLGIREQRVTGLMIFVLMGCSVFMTAILKFIPMPVLYG 856

Query: 736 VFLYMGISALGGIQFWDRCILLLKPVKHHPQLPYVRRVPTLKMHMYTLIQVGGVVVLYAV 795
           VFLYMG+S+L GIQF+DR  L   P KH P   Y+R VP  K+H++TLIQ+  +V+L+ +
Sbjct: 857 VFLYMGVSSLQGIQFFDRLKLFGMPAKHQPDFIYLRHVPLRKVHLFTLIQLTCLVLLWVI 916

Query: 796 KSSRFSLALPFFLVLMVPLRMSLVYIFTPLQLRALDGAQKDIDKDDEPDFYEEA 849
           K+S  ++  P  ++ +V +R  +   F+  +L  LD    +  K    D  ++A
Sbjct: 917 KASPAAIVFPMMVLALVFVRKVMDLCFSKRELSWLDDLMPESKKKKLDDAKKKA 970


>DQ063579-1|AAY79176.1| 1093|Homo sapiens Na+-driven Cl-HCO3
           exchanger protein.
          Length = 1093

 Score =  252 bits (617), Expect = 4e-66
 Identities = 140/364 (38%), Positives = 204/364 (56%), Gaps = 32/364 (8%)

Query: 93  LKRIPDDAEATTVLVGAVGFLDQPTIAFVRLAEGIYMPSITEVPVPVRFMFILLGPGGAD 152
           +K+IP  AEA+ VLVG V  LD+P +AFVRL+  + +  +TEVP+P RF+FILLGP G  
Sbjct: 291 MKKIPTGAEASNVLVGEVDILDRPIVAFVRLSPAVLLSGLTEVPIPTRFLFILLGPVGKG 350

Query: 153 LDYHEVGRSISTLMSNPAFHSIAYKADDRRELLSAINEFLDDSIVLPPGDWERQALLPLE 212
             YHE+GRS++T+M++  FH +AYKA +R +LL+ I+EFLD   VLPPG+W+    +   
Sbjct: 351 QQYHEIGRSMATIMTDEIFHDVAYKAKERDDLLAGIDEFLDQVTVLPPGEWDPSIRIEPP 410

Query: 213 ELRAKSEMIRRRKINALERKRIVADGDKPSDEKKALLAAEAGGMPPEEPDDPLSRTGRLF 272
           +     E   +RK+  +    +     +P            G   PE     L RTGRLF
Sbjct: 411 KNVPSQE---KRKMPGVPNGNVCHIEQEP----------HGGHSGPE-----LQRTGRLF 452

Query: 273 GGVIRDMKRRYPFYVSDFVDALNGQCVAATIFMYFAAVSSAITFGGLLAEKTYGKIGISE 332
           GG++ D+KR+ P+Y SD+ DAL+ QC+A+ +F+Y A +S  ITFGGLL E T G+I   E
Sbjct: 453 GGLVLDIKRKAPWYWSDYRDALSLQCLASFLFLYCACMSPVITFGGLLGEATEGRISAIE 512

Query: 333 TLSSGYVRSAVEGDLQVFTSAGGVLFALVAGQPMMITGATGPLLLLDESLANFCHSYGFD 392
           +L                 S  G+ ++L AGQ + I G+TGP+L+ ++ L  FC  Y   
Sbjct: 513 SLFG--------------ASMTGIAYSLFAGQALTILGSTGPVLVFEKILFKFCKDYALS 558

Query: 393 FLAARMYCGLWMIVIALCVASVEGSVAVKKITRFTEDXXXXXXXXXXXXEPITSTIAVYR 452
           +L+ R   GLW   + + + + + S  V  ITRFTE+            E I   I +  
Sbjct: 559 YLSLRACIGLWTAFLCIVLVATDASSLVCYITRFTEEAFASLICIIFIYEAIEKLIHLAE 618

Query: 453 ANPL 456
             P+
Sbjct: 619 TYPI 622



 Score =  207 bits (506), Expect = 1e-52
 Identities = 118/354 (33%), Positives = 194/354 (54%), Gaps = 21/354 (5%)

Query: 498  PPQPNTALFCTMLTLATFVLAYYLRIFRNGKFLGRSSATSRVQVTGRDGIQARRALGDFG 557
            P  P+   +  +L   TF+L+  L+ F+  ++       +RV          R  + DF 
Sbjct: 689  PYTPDVLFWSCILFFTTFILSSTLKTFKTSRYF-----PTRV----------RSMVSDFA 733

Query: 558  VPIAIVLMVGISCLVPVKTETLVVPAGLNPTTV-RSWFV-PLNPGLETIXXXXXXXXXXX 615
            V + I  MV I  L+ V +  L VP+   PT   R W + P+ P                
Sbjct: 734  VFLTIFTMVIIDFLIGVPSPKLQVPSVFKPTRDDRGWIINPIGPN----PWWTVIAAIIP 789

Query: 616  XXXVYIIVFMETHIAELIIAKPERRLKKGSGFHMDIVIMSFVNALCGMFGAPWQCVATVR 675
                 I++FM+  I  +II + E +LKKG G+H+D+++++ +  +C + G PW   ATV 
Sbjct: 790  ALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMVAIMLGVCSIMGLPWFVAATVL 849

Query: 676  SVSHVSALTIMSTTHAPGDKPHIVEVKEQRLTGLLVAVMVGISVLASGWLCLVPMAVLFG 735
            S++HV++L + S   APG++P  + ++EQR+TGL++ V++G SV  +  L  +PM VL+G
Sbjct: 850  SITHVNSLKLESECSAPGEQPKFLGIREQRVTGLMIFVLMGCSVFMTAILKFIPMPVLYG 909

Query: 736  VFLYMGISALGGIQFWDRCILLLKPVKHHPQLPYVRRVPTLKMHMYTLIQVGGVVVLYAV 795
            VFLYMG+S+L GIQF+DR  L   P KH P   Y+R VP  K+H++TLIQ+  +V+L+ +
Sbjct: 910  VFLYMGVSSLQGIQFFDRLKLFGMPAKHQPDFIYLRHVPLRKVHLFTLIQLTCLVLLWVI 969

Query: 796  KSSRFSLALPFFLVLMVPLRMSLVYIFTPLQLRALDGAQKDIDKDDEPDFYEEA 849
            K+S  ++  P  ++ +V +R  +   F+  +L  LD    +  K    D  ++A
Sbjct: 970  KASPAAIVFPMMVLALVFVRKVMDLCFSKRELSWLDDLMPESKKKKLDDAKKKA 1023


>BC025994-1|AAH25994.1|  691|Homo sapiens SLC4A8 protein protein.
          Length = 691

 Score =  252 bits (617), Expect = 4e-66
 Identities = 140/364 (38%), Positives = 204/364 (56%), Gaps = 32/364 (8%)

Query: 93  LKRIPDDAEATTVLVGAVGFLDQPTIAFVRLAEGIYMPSITEVPVPVRFMFILLGPGGAD 152
           +K+IP  AEA+ VLVG V  LD+P +AFVRL+  + +  +TEVP+P RF+FILLGP G  
Sbjct: 291 MKKIPTGAEASNVLVGEVDILDRPIVAFVRLSPAVLLSGLTEVPIPTRFLFILLGPVGKG 350

Query: 153 LDYHEVGRSISTLMSNPAFHSIAYKADDRRELLSAINEFLDDSIVLPPGDWERQALLPLE 212
             YHE+GRS++T+M++  FH +AYKA +R +LL+ I+EFLD   VLPPG+W+    +   
Sbjct: 351 QQYHEIGRSMATIMTDEIFHDVAYKAKERDDLLAGIDEFLDQVTVLPPGEWDPSIRIEPP 410

Query: 213 ELRAKSEMIRRRKINALERKRIVADGDKPSDEKKALLAAEAGGMPPEEPDDPLSRTGRLF 272
           +     E   +RK+  +    +     +P            G   PE     L RTGRLF
Sbjct: 411 KNVPSQE---KRKMPGVPNGNVCHIEQEP----------HGGHSGPE-----LQRTGRLF 452

Query: 273 GGVIRDMKRRYPFYVSDFVDALNGQCVAATIFMYFAAVSSAITFGGLLAEKTYGKIGISE 332
           GG++ D+KR+ P+Y SD+ DAL+ QC+A+ +F+Y A +S  ITFGGLL E T G+I   E
Sbjct: 453 GGLVLDIKRKAPWYWSDYRDALSLQCLASFLFLYCACMSPVITFGGLLGEATEGRISAIE 512

Query: 333 TLSSGYVRSAVEGDLQVFTSAGGVLFALVAGQPMMITGATGPLLLLDESLANFCHSYGFD 392
           +L                 S  G+ ++L AGQ + I G+TGP+L+ ++ L  FC  Y   
Sbjct: 513 SLFG--------------ASMTGIAYSLFAGQALTILGSTGPVLVFEKILFKFCKDYALS 558

Query: 393 FLAARMYCGLWMIVIALCVASVEGSVAVKKITRFTEDXXXXXXXXXXXXEPITSTIAVYR 452
           +L+ R   GLW   + + + + + S  V  ITRFTE+            E I   I +  
Sbjct: 559 YLSLRACIGLWTAFLCIVLVATDASSLVCYITRFTEEAFASLICIIFIYEAIEKLIHLAE 618

Query: 453 ANPL 456
             P+
Sbjct: 619 TYPI 622


>AF107099-1|AAD52981.1|  670|Homo sapiens sodium bicarbonate
           cotransporter isoform 3 protein.
          Length = 670

 Score =  252 bits (617), Expect = 4e-66
 Identities = 140/364 (38%), Positives = 204/364 (56%), Gaps = 32/364 (8%)

Query: 93  LKRIPDDAEATTVLVGAVGFLDQPTIAFVRLAEGIYMPSITEVPVPVRFMFILLGPGGAD 152
           +K+IP  AEA+ VLVG V  LD+P +AFVRL+  + +  +TEVP+P RF+FILLGP G  
Sbjct: 291 MKKIPTGAEASNVLVGEVDILDRPIVAFVRLSPAVLLSGLTEVPIPTRFLFILLGPVGKG 350

Query: 153 LDYHEVGRSISTLMSNPAFHSIAYKADDRRELLSAINEFLDDSIVLPPGDWERQALLPLE 212
             YHE+GRS++T+M++  FH +AYKA +R +LL+ I+EFLD   VLPPG+W+    +   
Sbjct: 351 QQYHEIGRSMATIMTDEIFHDVAYKAKERDDLLAGIDEFLDQVTVLPPGEWDPSIRIEPP 410

Query: 213 ELRAKSEMIRRRKINALERKRIVADGDKPSDEKKALLAAEAGGMPPEEPDDPLSRTGRLF 272
           +     E   +RK+  +    +     +P            G   PE     L RTGRLF
Sbjct: 411 KNVPSQE---KRKMPGVPNGNVCHIEQEP----------HGGHSGPE-----LQRTGRLF 452

Query: 273 GGVIRDMKRRYPFYVSDFVDALNGQCVAATIFMYFAAVSSAITFGGLLAEKTYGKIGISE 332
           GG++ D+KR+ P+Y SD+ DAL+ QC+A+ +F+Y A +S  ITFGGLL E T G+I   E
Sbjct: 453 GGLVLDIKRKAPWYWSDYRDALSLQCLASFLFLYCACMSPVITFGGLLGEATEGRISAIE 512

Query: 333 TLSSGYVRSAVEGDLQVFTSAGGVLFALVAGQPMMITGATGPLLLLDESLANFCHSYGFD 392
           +L                 S  G+ ++L AGQ + I G+TGP+L+ ++ L  FC  Y   
Sbjct: 513 SLFG--------------ASMTGIAYSLFAGQALTILGSTGPVLVFEKILFKFCKDYALS 558

Query: 393 FLAARMYCGLWMIVIALCVASVEGSVAVKKITRFTEDXXXXXXXXXXXXEPITSTIAVYR 452
           +L+ R   GLW   + + + + + S  V  ITRFTE+            E I   I +  
Sbjct: 559 YLSLRACIGLWTAFLCIVLVATDASSLVCYITRFTEEAFASLICIIFIYEAIEKLIHLAE 618

Query: 453 ANPL 456
             P+
Sbjct: 619 TYPI 622


>AF069512-1|AAC82380.1| 1044|Homo sapiens sodium bicarbonate
           cotransporter protein.
          Length = 1044

 Score =  252 bits (617), Expect = 4e-66
 Identities = 140/364 (38%), Positives = 204/364 (56%), Gaps = 32/364 (8%)

Query: 93  LKRIPDDAEATTVLVGAVGFLDQPTIAFVRLAEGIYMPSITEVPVPVRFMFILLGPGGAD 152
           +K+IP  AEA+ VLVG V  LD+P +AFVRL+  + +  +TEVP+P RF+FILLGP G  
Sbjct: 291 MKKIPTGAEASNVLVGEVDILDRPIVAFVRLSPAVLLSGLTEVPIPTRFLFILLGPVGKG 350

Query: 153 LDYHEVGRSISTLMSNPAFHSIAYKADDRRELLSAINEFLDDSIVLPPGDWERQALLPLE 212
             YHE+GRS++T+M++  FH +AYKA +R +LL+ I+EFLD   VLPPG+W+    +   
Sbjct: 351 QQYHEIGRSMATIMTDEIFHDVAYKAKERDDLLAGIDEFLDQVTVLPPGEWDPSIRIEPP 410

Query: 213 ELRAKSEMIRRRKINALERKRIVADGDKPSDEKKALLAAEAGGMPPEEPDDPLSRTGRLF 272
           +     E   +RK+  +    +     +P            G   PE     L RTGRLF
Sbjct: 411 KNVPSQE---KRKMPGVPNGNVCHIEQEP----------HGGHSGPE-----LQRTGRLF 452

Query: 273 GGVIRDMKRRYPFYVSDFVDALNGQCVAATIFMYFAAVSSAITFGGLLAEKTYGKIGISE 332
           GG++ D+KR+ P+Y SD+ DAL+ QC+A+ +F+Y A +S  ITFGGLL E T G+I   E
Sbjct: 453 GGLVLDIKRKAPWYWSDYRDALSLQCLASFLFLYCACMSPVITFGGLLGEATEGRISAIE 512

Query: 333 TLSSGYVRSAVEGDLQVFTSAGGVLFALVAGQPMMITGATGPLLLLDESLANFCHSYGFD 392
           +L                 S  G+ ++L AGQ + I G+TGP+L+ ++ L  FC  Y   
Sbjct: 513 SLFG--------------ASMTGIAYSLFAGQALTILGSTGPVLVFEKILFKFCKDYALS 558

Query: 393 FLAARMYCGLWMIVIALCVASVEGSVAVKKITRFTEDXXXXXXXXXXXXEPITSTIAVYR 452
           +L+ R   GLW   + + + + + S  V  ITRFTE+            E I   I +  
Sbjct: 559 YLSLRACIGLWTAFLCIVLVATDASSLVCYITRFTEEAFASLICIIFIYEAIEKLIHLAE 618

Query: 453 ANPL 456
             P+
Sbjct: 619 TYPI 622



 Score =  207 bits (505), Expect = 1e-52
 Identities = 118/354 (33%), Positives = 194/354 (54%), Gaps = 21/354 (5%)

Query: 498  PPQPNTALFCTMLTLATFVLAYYLRIFRNGKFLGRSSATSRVQVTGRDGIQARRALGDFG 557
            P  P+   +  +L   TF+L+  L+ F+  ++       +RV          R  + DF 
Sbjct: 689  PYTPDVLFWSCILFFTTFILSSTLKTFKTSRYF-----PTRV----------RSMVSDFA 733

Query: 558  VPIAIVLMVGISCLVPVKTETLVVPAGLNPTTV-RSWFV-PLNPGLETIXXXXXXXXXXX 615
            V + I  MV I  L+ V +  L VP+   PT   R W + P+ P                
Sbjct: 734  VFLTIFTMVIIDFLIGVPSPKLQVPSVFKPTRDDRGWIINPIGPN----PWWTVIAAIIP 789

Query: 616  XXXVYIIVFMETHIAELIIAKPERRLKKGSGFHMDIVIMSFVNALCGMFGAPWQCVATVR 675
                 I++FM+  I  +II + E +LKKG G+H+D+++++ +  +C + G PW   ATV 
Sbjct: 790  ALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMVAIMLGVCSIMGLPWFVAATVL 849

Query: 676  SVSHVSALTIMSTTHAPGDKPHIVEVKEQRLTGLLVAVMVGISVLASGWLCLVPMAVLFG 735
            S++HV++L + S   APG++P  + ++EQR+TGL++ V++G SV  +  L  +PM VL+G
Sbjct: 850  SITHVNSLKLESECSAPGEQPKFLGIREQRVTGLMIFVLMGCSVFMTAILKFIPMPVLYG 909

Query: 736  VFLYMGISALGGIQFWDRCILLLKPVKHHPQLPYVRRVPTLKMHMYTLIQVGGVVVLYAV 795
            VFLYMG+S+L GIQF+DR  L   P KH P   Y+R VP  K+H++TLIQ+  +V+L+ +
Sbjct: 910  VFLYMGVSSLQGIQFFDRLKLFGMPAKHQPDFIYLRHVPLRKVHLFTLIQLTCLVLLWVI 969

Query: 796  KSSRFSLALPFFLVLMVPLRMSLVYIFTPLQLRALDGAQKDIDKDDEPDFYEEA 849
            K+S  ++  P  ++ +V +R  +   F+  +L  LD    +  K    D  ++A
Sbjct: 970  KASPAAIVFPMMVLALVFVRKVMDLCFSKRELSWLDDLTPESKKKKLDDAKKKA 1023


>AB018282-1|BAA34459.1| 1130|Homo sapiens KIAA0739 protein protein.
          Length = 1130

 Score =  252 bits (617), Expect = 4e-66
 Identities = 140/364 (38%), Positives = 204/364 (56%), Gaps = 32/364 (8%)

Query: 93  LKRIPDDAEATTVLVGAVGFLDQPTIAFVRLAEGIYMPSITEVPVPVRFMFILLGPGGAD 152
           +K+IP  AEA+ VLVG V  LD+P +AFVRL+  + +  +TEVP+P RF+FILLGP G  
Sbjct: 377 MKKIPTGAEASNVLVGEVDILDRPIVAFVRLSPAVLLSGLTEVPIPTRFLFILLGPVGKG 436

Query: 153 LDYHEVGRSISTLMSNPAFHSIAYKADDRRELLSAINEFLDDSIVLPPGDWERQALLPLE 212
             YHE+GRS++T+M++  FH +AYKA +R +LL+ I+EFLD   VLPPG+W+    +   
Sbjct: 437 QQYHEIGRSMATIMTDEIFHDVAYKAKERDDLLAGIDEFLDQVTVLPPGEWDPSIRIEPP 496

Query: 213 ELRAKSEMIRRRKINALERKRIVADGDKPSDEKKALLAAEAGGMPPEEPDDPLSRTGRLF 272
           +     E   +RK+  +    +     +P            G   PE     L RTGRLF
Sbjct: 497 KNVPSQE---KRKMPGVPNGNVCHIEQEP----------HGGHSGPE-----LQRTGRLF 538

Query: 273 GGVIRDMKRRYPFYVSDFVDALNGQCVAATIFMYFAAVSSAITFGGLLAEKTYGKIGISE 332
           GG++ D+KR+ P+Y SD+ DAL+ QC+A+ +F+Y A +S  ITFGGLL E T G+I   E
Sbjct: 539 GGLVLDIKRKAPWYWSDYRDALSLQCLASFLFLYCACMSPVITFGGLLGEATEGRISAIE 598

Query: 333 TLSSGYVRSAVEGDLQVFTSAGGVLFALVAGQPMMITGATGPLLLLDESLANFCHSYGFD 392
           +L                 S  G+ ++L AGQ + I G+TGP+L+ ++ L  FC  Y   
Sbjct: 599 SLFG--------------ASMTGIAYSLFAGQALTILGSTGPVLVFEKILFKFCKDYALS 644

Query: 393 FLAARMYCGLWMIVIALCVASVEGSVAVKKITRFTEDXXXXXXXXXXXXEPITSTIAVYR 452
           +L+ R   GLW   + + + + + S  V  ITRFTE+            E I   I +  
Sbjct: 645 YLSLRACIGLWTAFLCIVLVATDASSLVCYITRFTEEAFASLICIIFIYEAIEKLIHLAE 704

Query: 453 ANPL 456
             P+
Sbjct: 705 TYPI 708



 Score =  207 bits (506), Expect = 1e-52
 Identities = 118/354 (33%), Positives = 194/354 (54%), Gaps = 21/354 (5%)

Query: 498  PPQPNTALFCTMLTLATFVLAYYLRIFRNGKFLGRSSATSRVQVTGRDGIQARRALGDFG 557
            P  P+   +  +L   TF+L+  L+ F+  ++       +RV          R  + DF 
Sbjct: 775  PYTPDVLFWSCILFFTTFILSSTLKTFKTSRYF-----PTRV----------RSMVSDFA 819

Query: 558  VPIAIVLMVGISCLVPVKTETLVVPAGLNPTTV-RSWFV-PLNPGLETIXXXXXXXXXXX 615
            V + I  MV I  L+ V +  L VP+   PT   R W + P+ P                
Sbjct: 820  VFLTIFTMVIIDFLIGVPSPKLQVPSVFKPTRDDRGWIINPIGPN----PWWTVIAAIIP 875

Query: 616  XXXVYIIVFMETHIAELIIAKPERRLKKGSGFHMDIVIMSFVNALCGMFGAPWQCVATVR 675
                 I++FM+  I  +II + E +LKKG G+H+D+++++ +  +C + G PW   ATV 
Sbjct: 876  ALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMVAIMLGVCSIMGLPWFVAATVL 935

Query: 676  SVSHVSALTIMSTTHAPGDKPHIVEVKEQRLTGLLVAVMVGISVLASGWLCLVPMAVLFG 735
            S++HV++L + S   APG++P  + ++EQR+TGL++ V++G SV  +  L  +PM VL+G
Sbjct: 936  SITHVNSLKLESECSAPGEQPKFLGIREQRVTGLMIFVLMGCSVFMTAILKFIPMPVLYG 995

Query: 736  VFLYMGISALGGIQFWDRCILLLKPVKHHPQLPYVRRVPTLKMHMYTLIQVGGVVVLYAV 795
            VFLYMG+S+L GIQF+DR  L   P KH P   Y+R VP  K+H++TLIQ+  +V+L+ +
Sbjct: 996  VFLYMGVSSLQGIQFFDRLKLFGMPAKHQPDFIYLRHVPLRKVHLFTLIQLTCLVLLWVI 1055

Query: 796  KSSRFSLALPFFLVLMVPLRMSLVYIFTPLQLRALDGAQKDIDKDDEPDFYEEA 849
            K+S  ++  P  ++ +V +R  +   F+  +L  LD    +  K    D  ++A
Sbjct: 1056 KASPAAIVFPMMVLALVFVRKVMDLCFSKRELSWLDDLMPESKKKKLDDAKKKA 1109


>AF453528-1|AAL50802.1|  760|Homo sapiens sodium bicarbonate
           cotransporter 4f protein.
          Length = 760

 Score =  244 bits (596), Expect = 1e-63
 Identities = 154/449 (34%), Positives = 236/449 (52%), Gaps = 47/449 (10%)

Query: 74  LAHA-SESQDELRRTHN-----DSILKRIPDDAEATTVLVGAVGFLDQPTIAFVRLAEGI 127
           L HA S S +++  T N     +  +K+IP D+EA+ VLVG V FLDQP IAFVRL +  
Sbjct: 270 LCHAQSRSMNDISLTPNTDQRKNKFMKKIPKDSEASNVLVGEVDFLDQPFIAFVRLIQSA 329

Query: 128 YMPSITEVPVPVRFMFILLGPGGADLDYHEVGRSISTLMSNPAFHSIAYKADDRRELLSA 187
            +  +TEVPVP RF+FILLGP G    Y+E+GR+I+TLM +  F  +AYKA +R +L++ 
Sbjct: 330 MLGGVTEVPVPTRFLFILLGPSGRAKSYNEIGRAIATLMVDDLFSDVAYKARNREDLIAG 389

Query: 188 INEFLDDSIVLPPGDWERQALLPLEELRAKSEMIRRRKINALE-----RKRIVADGDKPS 242
           I+EFLD+ IVLPPG+W+    + +E  +      +R+ + +L         +   G  P 
Sbjct: 390 IDEFLDEVIVLPPGEWDPN--IRIEPPKKVPSADKRKSVFSLAELGQMNGSVGGGGGAPG 447

Query: 243 DEKKALLAAEAGG-----------------MPP-EEPDDPLSRTGRLFGGVIRDMKRRYP 284
                     +GG                 MP   E  + L  TGR FGG+  D+KR+ P
Sbjct: 448 GGNGGGGGGGSGGGAGSGGAGGTSSGDDGEMPAMHEIGEELIWTGRFFGGLCLDIKRKLP 507

Query: 285 FYVSDFVDALNGQCVAATIFMYFAAVSSAITFGGLLAEKTYGKIGISETLSSGYVRSAVE 344
           ++ SDF D  + Q ++A +F+Y   +++AITFGGLL + T    G+ E+           
Sbjct: 508 WFPSDFYDGFHIQSISAILFIYLGCITNAITFGGLLGDATDNYQGVMESF---------- 557

Query: 345 GDLQVFTSAGGVLFALVAGQPMMITGATGPLLLLDESLANFCHSYGFDFLAARMYCGLWM 404
               + T+  G LF L +GQP++I  +TGP+L+ ++ L +F    G D++  R++ GL+ 
Sbjct: 558 ----LGTAMAGSLFCLFSGQPLIILSSTGPILIFEKLLFDFSKGNGLDYMEFRLWIGLYS 613

Query: 405 IVIALCVASVEGSVAVKKITRFTEDXXXXXXXXXXXXEPITSTIAVYRANPLGIDYCQFR 464
            V  L + + + S  +K ITRFTE+            + I   I  ++  P+ +D+    
Sbjct: 614 AVQCLILVATDASFIIKYITRFTEEGFSTLISFIFIYDAIKKMIGAFKYYPINMDFKPNF 673

Query: 465 EVALSNSTVQPLLNSTSVGNSSVVAPAPP 493
                   V P   +T+V N+S  AP  P
Sbjct: 674 ITTYKCECVAPDTVNTTVFNAS--APLAP 700


>X87211-1|CAA60670.1|  357|Homo sapiens anion exchange protein
           protein.
          Length = 357

 Score =  241 bits (591), Expect = 6e-63
 Identities = 138/383 (36%), Positives = 204/383 (53%), Gaps = 30/383 (7%)

Query: 385 FCHSYGFDFLAARMYCGLWMIVIALCVASVEGSVAVKKITRFTEDXXXXXXXXXXXXEPI 444
           FC +   ++L  R++ GLW++V  L + + E S  V+ I+ FT++            E  
Sbjct: 1   FCRAQDLEYLTGRVWVGLWLVVFVLALVAAERSFLVRYISPFTQEIFAFLISLIFIYETF 60

Query: 445 TSTIAVYRANPLGIDYCQFREVALSNSTVQPLLNSTSVGNSSVVAPAPPVSRLPP--QPN 502
                V+  +PL           L     +         + +     PP     P  QPN
Sbjct: 61  YKLYKVFTEHPL-----------LPFYPPEAPGGVPGCWSGAKWQALPPTEGPGPRNQPN 109

Query: 503 TALFCTMLTLATFVLAYYLRIFRNGKFLGRSSATSRVQVTGRDGIQARRALGDFGVPIAI 562
           TAL   +L L TF +A++LR FRN +F G                +ARR +GDFG+P  +
Sbjct: 110 TALLSLILILGTFFIAFFLRKFRNSRFWGG---------------KARRIIGDFGIPSIL 154

Query: 563 VLMVGISCLVPVKTETLVVPAGLNPTT--VRSWFVPLNPGLETIXXXXXXXXXXXXXXVY 620
           V+++    +    T  L VP GL+ T+   RSWF+P                      V 
Sbjct: 155 VMVLVDYSITDTYTGKLTVPTGLSVTSPDKRSWFIPPLGSARPFPPWMMVAAAVPALLVL 214

Query: 621 IIVFMETHIAELIIAKPERRLKKGSGFHMDIVIMSFVNALCGMFGAPWQCVATVRSVSHV 680
           I++FMET I  LI+++  RRL KGSGFH+D++++  +  L G+FG PW   ATVR V+HV
Sbjct: 215 ILIFMETQITALIVSQKARRLLKGSGFHLDLLLIGSLGGLRGLFGLPWLTAATVRHVTHV 274

Query: 681 SALTIMSTTHAPGDKPHIVEVKEQRLTGLLVAVMVGISVLASGWLCLVPMAVLFGVFLYM 740
           +ALT+M T  APGDKP I EV+EQR+TG+L+A +VG+S++    L  +P+AVLFG+FLYM
Sbjct: 275 NALTVMRTAIAPGDKPQIQEVREQRVTGVLIASLVGLSIVMGAVLRRIPLAVLFGIFLYM 334

Query: 741 GISALGGIQFWDRCILLLKPVKH 763
           G+++L GIQ   + +L+  P KH
Sbjct: 335 GVTSLSGIQLSQQLLLIFMPAKH 357


>X70797-1|CAA50067.1|  357|Homo sapiens anion exchange protein 3
           protein.
          Length = 357

 Score =  241 bits (591), Expect = 6e-63
 Identities = 138/383 (36%), Positives = 204/383 (53%), Gaps = 30/383 (7%)

Query: 385 FCHSYGFDFLAARMYCGLWMIVIALCVASVEGSVAVKKITRFTEDXXXXXXXXXXXXEPI 444
           FC +   ++L  R++ GLW++V  L + + E S  V+ I+ FT++            E  
Sbjct: 1   FCRAQDLEYLTGRVWVGLWLVVFVLALVAAERSFLVRYISPFTQEIFAFLISLIFIYETF 60

Query: 445 TSTIAVYRANPLGIDYCQFREVALSNSTVQPLLNSTSVGNSSVVAPAPPVSRLPP--QPN 502
                V+  +PL           L     +         + +     PP     P  QPN
Sbjct: 61  YKLYKVFTEHPL-----------LPFYPPEAPGGVPGCWSGAKWQALPPTEGPGPRNQPN 109

Query: 503 TALFCTMLTLATFVLAYYLRIFRNGKFLGRSSATSRVQVTGRDGIQARRALGDFGVPIAI 562
           TAL   +L L TF +A++LR FRN +F G                +ARR +GDFG+P  +
Sbjct: 110 TALLSLILMLGTFFIAFFLRKFRNSRFWGG---------------KARRIIGDFGIPSIL 154

Query: 563 VLMVGISCLVPVKTETLVVPAGLNPTT--VRSWFVPLNPGLETIXXXXXXXXXXXXXXVY 620
           V+++    +    T  L VP GL+ T+   RSWF+P                      V 
Sbjct: 155 VMVLVDYSITDTYTGKLTVPTGLSVTSPDKRSWFIPPLGSARPFPPWMMVAAAVPALLVL 214

Query: 621 IIVFMETHIAELIIAKPERRLKKGSGFHMDIVIMSFVNALCGMFGAPWQCVATVRSVSHV 680
           I++FMET I  LI+++  RRL KGSGFH+D++++  +  L G+FG PW   ATVR V+HV
Sbjct: 215 ILIFMETQITALIVSQKARRLLKGSGFHLDLLLIGSLGGLRGLFGLPWLTAATVRHVTHV 274

Query: 681 SALTIMSTTHAPGDKPHIVEVKEQRLTGLLVAVMVGISVLASGWLCLVPMAVLFGVFLYM 740
           +ALT+M T  APGDKP I EV+EQR+TG+L+A +VG+S++    L  +P+AVLFG+FLYM
Sbjct: 275 NALTVMRTAIAPGDKPQIQEVREQRVTGVLIASLVGLSIVMGAVLRRIPLAVLFGIFLYM 334

Query: 741 GISALGGIQFWDRCILLLKPVKH 763
           G+++L GIQ   + +L+  P KH
Sbjct: 335 GVTSLSGIQLSQQLLLIFMPAKH 357


>AL109976-2|CAB90170.4|  918|Homo sapiens solute carrier family 4,
           sodium bicarbonate transporter-like, member 11 protein.
          Length = 918

 Score =  189 bits (461), Expect = 3e-47
 Identities = 161/578 (27%), Positives = 259/578 (44%), Gaps = 54/578 (9%)

Query: 261 PDDPLSRTGRLFG-GVIRDMKRRYPFYVSDFVDALNGQ------CVAATIFMYFAAVSSA 313
           P+ P  +    FG G+  D+ RR+P Y  DF D + G+       +  T+F+YFA +   
Sbjct: 358 PEPPKCKDFVPFGKGIREDIARRFPLYPLDFTDGIIGKNKAVGKYITTTLFLYFACLLPT 417

Query: 314 ITFGGLLAEKTYGKIGISETLSSGYVRSAVEGDLQVFTSAGGVLFALVAGQPMMITGATG 373
           I FG L  E T G I + +T++                S GG+L+AL +GQP++I   T 
Sbjct: 418 IAFGSLNDENTDGAIDVQKTIAG--------------QSIGGLLYALFSGQPLVILLTTA 463

Query: 374 PLLLLDESLANFCHSYGFDFLAARMYCGLWMIVIALCVASVEGSVAVKKITRFTEDXXXX 433
           PL L  + +   C  Y  DF +   + GLW        A    S+ +    R TE+    
Sbjct: 464 PLALYIQVIRVICDDYDLDFNSFYAWTGLWNSFFLALYAFFNLSLVMSLFKRSTEEIIAL 523

Query: 434 XXXXXXXXEPITSTIAVYRANPLGI---DYCQFREVAL-SNSTVQPLLNS---TSVGNSS 486
                   + +  T+ ++     G    DY   R  +L S S +   LN+   T++  S 
Sbjct: 524 FISITFVLDAVKGTVKIFWKYYYGHYLDDYHTKRTSSLVSLSGLGASLNASLHTALNASF 583

Query: 487 VVAPAPPVSRLPPQPNTALFCTMLTLATFVLAYYLRIFRNGKFLGRSSATSRVQVTGRDG 546
           + +P    S       TA+   ++ L T  L Y L  F+   +L                
Sbjct: 584 LASPTELPSATHSGQATAVLSLLIMLGTLWLGYTLYQFKKSPYLHPC------------- 630

Query: 547 IQARRALGDFGVPIAIVLMVGISCLVPVKTETLVVPAGLNPTTVRSWFVPLNPGLETIXX 606
              R  L D  +PIA++    IS     + E  +     NP+   S F      ++++  
Sbjct: 631 --VREILSDCALPIAVLAFSLISSHGFREIE--MSKFRYNPS--ESPFAMAQ--IQSLSL 682

Query: 607 XXXXXXXXXXXXVYIIVFMETHIAELIIAKPERRLKKGSGFHMDIVIMSFVNALCGMFGA 666
                       + ++ F+E ++   ++  PE RL KG+ +H D+++++ +N    +FG 
Sbjct: 683 RAVSGAMGLGFLLSMLFFIEQNLVAALVNAPENRLVKGTAYHWDLLLLAIINTGLSLFGL 742

Query: 667 PWQCVATVRSVSHVSALTIMSTTHAPGD-KPHIVEVKEQRLTGLLVAVMVGISVLASGW- 724
           PW   A   S  HV AL ++      G     IV VKE RLT L  +V+VG+S+L     
Sbjct: 743 PWIHAAYPHSPLHVRALALVEERVENGHIYDTIVNVKETRLTSLGASVLVGLSLLLLPVP 802

Query: 725 LCLVPMAVLFGVFLYMGISALGGIQFWDRCILLLKPVKHHPQLPYVRRVPTLKMHMYTLI 784
           L  +P  VL+G+FLY+ +++L G Q   R  LLLK    +P   Y+RRVP  K+H +T +
Sbjct: 803 LQWIPKPVLYGLFLYIALTSLDGNQLVQRVALLLKEQTAYPPTHYIRRVPQRKIHYFTGL 862

Query: 785 QVGGVVVLYAVKSSR---FSLALPFFLVLMVPLRMSLV 819
           QV  +++L A   S      +  P  ++ M+P+R  L+
Sbjct: 863 QVLQLLLLCAFGMSSLPYMKMIFPLIMIAMIPIRYILL 900


>AL109976-1|CAD55941.1|  891|Homo sapiens solute carrier family 4,
           sodium bicarbonate transporter-like, member 11 protein.
          Length = 891

 Score =  189 bits (461), Expect = 3e-47
 Identities = 161/578 (27%), Positives = 259/578 (44%), Gaps = 54/578 (9%)

Query: 261 PDDPLSRTGRLFG-GVIRDMKRRYPFYVSDFVDALNGQ------CVAATIFMYFAAVSSA 313
           P+ P  +    FG G+  D+ RR+P Y  DF D + G+       +  T+F+YFA +   
Sbjct: 331 PEPPKCKDFVPFGKGIREDIARRFPLYPLDFTDGIIGKNKAVGKYITTTLFLYFACLLPT 390

Query: 314 ITFGGLLAEKTYGKIGISETLSSGYVRSAVEGDLQVFTSAGGVLFALVAGQPMMITGATG 373
           I FG L  E T G I + +T++                S GG+L+AL +GQP++I   T 
Sbjct: 391 IAFGSLNDENTDGAIDVQKTIAG--------------QSIGGLLYALFSGQPLVILLTTA 436

Query: 374 PLLLLDESLANFCHSYGFDFLAARMYCGLWMIVIALCVASVEGSVAVKKITRFTEDXXXX 433
           PL L  + +   C  Y  DF +   + GLW        A    S+ +    R TE+    
Sbjct: 437 PLALYIQVIRVICDDYDLDFNSFYAWTGLWNSFFLALYAFFNLSLVMSLFKRSTEEIIAL 496

Query: 434 XXXXXXXXEPITSTIAVYRANPLGI---DYCQFREVAL-SNSTVQPLLNS---TSVGNSS 486
                   + +  T+ ++     G    DY   R  +L S S +   LN+   T++  S 
Sbjct: 497 FISITFVLDAVKGTVKIFWKYYYGHYLDDYHTKRTSSLVSLSGLGASLNASLHTALNASF 556

Query: 487 VVAPAPPVSRLPPQPNTALFCTMLTLATFVLAYYLRIFRNGKFLGRSSATSRVQVTGRDG 546
           + +P    S       TA+   ++ L T  L Y L  F+   +L                
Sbjct: 557 LASPTELPSATHSGQATAVLSLLIMLGTLWLGYTLYQFKKSPYLHPC------------- 603

Query: 547 IQARRALGDFGVPIAIVLMVGISCLVPVKTETLVVPAGLNPTTVRSWFVPLNPGLETIXX 606
              R  L D  +PIA++    IS     + E  +     NP+   S F      ++++  
Sbjct: 604 --VREILSDCALPIAVLAFSLISSHGFREIE--MSKFRYNPS--ESPFAMAQ--IQSLSL 655

Query: 607 XXXXXXXXXXXXVYIIVFMETHIAELIIAKPERRLKKGSGFHMDIVIMSFVNALCGMFGA 666
                       + ++ F+E ++   ++  PE RL KG+ +H D+++++ +N    +FG 
Sbjct: 656 RAVSGAMGLGFLLSMLFFIEQNLVAALVNAPENRLVKGTAYHWDLLLLAIINTGLSLFGL 715

Query: 667 PWQCVATVRSVSHVSALTIMSTTHAPGD-KPHIVEVKEQRLTGLLVAVMVGISVLASGW- 724
           PW   A   S  HV AL ++      G     IV VKE RLT L  +V+VG+S+L     
Sbjct: 716 PWIHAAYPHSPLHVRALALVEERVENGHIYDTIVNVKETRLTSLGASVLVGLSLLLLPVP 775

Query: 725 LCLVPMAVLFGVFLYMGISALGGIQFWDRCILLLKPVKHHPQLPYVRRVPTLKMHMYTLI 784
           L  +P  VL+G+FLY+ +++L G Q   R  LLLK    +P   Y+RRVP  K+H +T +
Sbjct: 776 LQWIPKPVLYGLFLYIALTSLDGNQLVQRVALLLKEQTAYPPTHYIRRVPQRKIHYFTGL 835

Query: 785 QVGGVVVLYAVKSSR---FSLALPFFLVLMVPLRMSLV 819
           QV  +++L A   S      +  P  ++ M+P+R  L+
Sbjct: 836 QVLQLLLLCAFGMSSLPYMKMIFPLIMIAMIPIRYILL 873


>AK075303-1|BAC11536.1|  633|Homo sapiens protein ( Homo sapiens
           cDNA FLJ90822 fis, clone Y79AA1001426, weakly similar to
           ANION EXCHANGE PROTEIN 3. ).
          Length = 633

 Score =  189 bits (461), Expect = 3e-47
 Identities = 161/578 (27%), Positives = 259/578 (44%), Gaps = 54/578 (9%)

Query: 261 PDDPLSRTGRLFG-GVIRDMKRRYPFYVSDFVDALNGQ------CVAATIFMYFAAVSSA 313
           P+ P  +    FG G+  D+ RR+P Y  DF D + G+       +  T+F+YFA +   
Sbjct: 73  PEPPKCKDFVPFGKGIREDIARRFPLYPLDFTDGIIGKNKAVGKYITTTLFLYFACLLPT 132

Query: 314 ITFGGLLAEKTYGKIGISETLSSGYVRSAVEGDLQVFTSAGGVLFALVAGQPMMITGATG 373
           I FG L  E T G I + +T++                S GG+L+AL +GQP++I   T 
Sbjct: 133 IAFGSLNDENTDGAIDVQKTIAG--------------QSIGGLLYALFSGQPLVILLTTA 178

Query: 374 PLLLLDESLANFCHSYGFDFLAARMYCGLWMIVIALCVASVEGSVAVKKITRFTEDXXXX 433
           PL L  + +   C  Y  DF +   + GLW        A    S+ +    R TE+    
Sbjct: 179 PLALYIQVIRVICDDYDLDFNSFYAWTGLWNSFFLALYAFFNLSLVMSLFKRSTEEIIAL 238

Query: 434 XXXXXXXXEPITSTIAVYRANPLGI---DYCQFREVAL-SNSTVQPLLNS---TSVGNSS 486
                   + +  T+ ++     G    DY   R  +L S S +   LN+   T++  S 
Sbjct: 239 FISITFVLDAVKGTVKIFWKYYYGHYLDDYHTKRTSSLVSLSGLGASLNASLHTALNASF 298

Query: 487 VVAPAPPVSRLPPQPNTALFCTMLTLATFVLAYYLRIFRNGKFLGRSSATSRVQVTGRDG 546
           + +P    S       TA+   ++ L T  L Y L  F+   +L                
Sbjct: 299 LASPTELPSATHSGQATAVLSLLIMLGTLWLGYTLYQFKKSPYLHPC------------- 345

Query: 547 IQARRALGDFGVPIAIVLMVGISCLVPVKTETLVVPAGLNPTTVRSWFVPLNPGLETIXX 606
              R  L D  +PIA++    IS     + E  +     NP+   S F      ++++  
Sbjct: 346 --VREILSDCALPIAVLAFSLISSHGFREIE--MSKFRYNPS--ESPFAMAQ--IQSLSL 397

Query: 607 XXXXXXXXXXXXVYIIVFMETHIAELIIAKPERRLKKGSGFHMDIVIMSFVNALCGMFGA 666
                       + ++ F+E ++   ++  PE RL KG+ +H D+++++ +N    +FG 
Sbjct: 398 RAVSGAMGLGFLLSMLFFIEQNLVAALVNAPENRLVKGTAYHWDLLLLAIINTGLSLFGL 457

Query: 667 PWQCVATVRSVSHVSALTIMSTTHAPGD-KPHIVEVKEQRLTGLLVAVMVGISVLASGW- 724
           PW   A   S  HV AL ++      G     IV VKE RLT L  +V+VG+S+L     
Sbjct: 458 PWIHAAYPHSPLHVRALALVEERVENGHIYDTIVNVKETRLTSLGASVLVGLSLLLLPVP 517

Query: 725 LCLVPMAVLFGVFLYMGISALGGIQFWDRCILLLKPVKHHPQLPYVRRVPTLKMHMYTLI 784
           L  +P  VL+G+FLY+ +++L G Q   R  LLLK    +P   Y+RRVP  K+H +T +
Sbjct: 518 LQWIPKPVLYGLFLYIALTSLDGNQLVQRVALLLKEQTAYPPTHYIRRVPQRKIHYFTGL 577

Query: 785 QVGGVVVLYAVKSSR---FSLALPFFLVLMVPLRMSLV 819
           QV  +++L A   S      +  P  ++ M+P+R  L+
Sbjct: 578 QVLQLLLLCAFGMSSLPYMKMIFPLIMIAMIPIRYILL 615


>AF336127-1|AAK16734.1|  891|Homo sapiens bicarbonate
           transporter-related protein BTR1 protein.
          Length = 891

 Score =  189 bits (461), Expect = 3e-47
 Identities = 161/578 (27%), Positives = 259/578 (44%), Gaps = 54/578 (9%)

Query: 261 PDDPLSRTGRLFG-GVIRDMKRRYPFYVSDFVDALNGQ------CVAATIFMYFAAVSSA 313
           P+ P  +    FG G+  D+ RR+P Y  DF D + G+       +  T+F+YFA +   
Sbjct: 331 PEPPKCKDFVPFGKGIREDIARRFPLYPLDFTDGIIGKNKAVGKYITTTLFLYFACLLPT 390

Query: 314 ITFGGLLAEKTYGKIGISETLSSGYVRSAVEGDLQVFTSAGGVLFALVAGQPMMITGATG 373
           I FG L  E T G I + +T++                S GG+L+AL +GQP++I   T 
Sbjct: 391 IAFGSLNDENTDGAIDVQKTIAG--------------QSIGGLLYALFSGQPLVILLTTA 436

Query: 374 PLLLLDESLANFCHSYGFDFLAARMYCGLWMIVIALCVASVEGSVAVKKITRFTEDXXXX 433
           PL L  + +   C  Y  DF +   + GLW        A    S+ +    R TE+    
Sbjct: 437 PLALYIQVIRVICDDYDLDFNSFYAWTGLWNSFFLALYAFFNLSLVMSLFKRSTEEIIAL 496

Query: 434 XXXXXXXXEPITSTIAVYRANPLGI---DYCQFREVAL-SNSTVQPLLNS---TSVGNSS 486
                   + +  T+ ++     G    DY   R  +L S S +   LN+   T++  S 
Sbjct: 497 FISITFVLDAVKGTVKIFWKYYYGHYLDDYHTKRTSSLVSLSGLGASLNASLHTALNASF 556

Query: 487 VVAPAPPVSRLPPQPNTALFCTMLTLATFVLAYYLRIFRNGKFLGRSSATSRVQVTGRDG 546
           + +P    S       TA+   ++ L T  L Y L  F+   +L                
Sbjct: 557 LASPTELPSATHSGQATAVLSLLIMLGTLWLGYTLYQFKKSPYLHPC------------- 603

Query: 547 IQARRALGDFGVPIAIVLMVGISCLVPVKTETLVVPAGLNPTTVRSWFVPLNPGLETIXX 606
              R  L D  +PIA++    IS     + E  +     NP+   S F      ++++  
Sbjct: 604 --VREILSDCALPIAVLAFSLISSHGFREIE--MSKFRYNPS--ESPFAMAQ--IQSLSL 655

Query: 607 XXXXXXXXXXXXVYIIVFMETHIAELIIAKPERRLKKGSGFHMDIVIMSFVNALCGMFGA 666
                       + ++ F+E ++   ++  PE RL KG+ +H D+++++ +N    +FG 
Sbjct: 656 RAVSGAMGLGFLLSMLFFIEQNLVAALVNAPENRLVKGTAYHWDLLLLAIINTGLSLFGL 715

Query: 667 PWQCVATVRSVSHVSALTIMSTTHAPGD-KPHIVEVKEQRLTGLLVAVMVGISVLASGW- 724
           PW   A   S  HV AL ++      G     IV VKE RLT L  +V+VG+S+L     
Sbjct: 716 PWIHAAYPHSPLHVRALALVEERVENGHIYDTIVNVKETRLTSLGASVLVGLSLLLLPVP 775

Query: 725 LCLVPMAVLFGVFLYMGISALGGIQFWDRCILLLKPVKHHPQLPYVRRVPTLKMHMYTLI 784
           L  +P  VL+G+FLY+ +++L G Q   R  LLLK    +P   Y+RRVP  K+H +T +
Sbjct: 776 LQWIPKPVLYGLFLYIALTSLDGNQLVQRVALLLKEQTAYPPTHYIRRVPQRKIHYFTGL 835

Query: 785 QVGGVVVLYAVKSSR---FSLALPFFLVLMVPLRMSLV 819
           QV  +++L A   S      +  P  ++ M+P+R  L+
Sbjct: 836 QVLQLLLLCAFGMSSLPYMKMIFPLIMIAMIPIRYILL 873


>BC110540-1|AAI10541.1|  891|Homo sapiens solute carrier family 4,
           sodium bicarbonate transporter-like, member 11 protein.
          Length = 891

 Score =  187 bits (455), Expect = 2e-46
 Identities = 160/578 (27%), Positives = 258/578 (44%), Gaps = 54/578 (9%)

Query: 261 PDDPLSRTGRLFG-GVIRDMKRRYPFYVSDFVDALNGQ------CVAATIFMYFAAVSSA 313
           P+ P  +    FG G+  D+ RR+P Y  DF D + G+       +  T+F+YFA +   
Sbjct: 331 PEPPKCKDFVPFGKGIREDIARRFPLYPLDFTDGIIGKNKAVGKYITTTLFLYFACLLPT 390

Query: 314 ITFGGLLAEKTYGKIGISETLSSGYVRSAVEGDLQVFTSAGGVLFALVAGQPMMITGATG 373
           I FG L  E T G I + +T++                S GG+L+AL +GQP++I   T 
Sbjct: 391 IAFGSLNDENTDGAIDVQKTIAG--------------QSIGGLLYALFSGQPLVILLTTA 436

Query: 374 PLLLLDESLANFCHSYGFDFLAARMYCGLWMIVIALCVASVEGSVAVKKITRFTEDXXXX 433
           PL L  + +   C  Y  DF +   + GLW        A    S+ +    R TE+    
Sbjct: 437 PLALYIQVIRVICDDYDLDFNSFYAWTGLWNSFFLALYAFFNLSLVMSLFKRSTEEIIAL 496

Query: 434 XXXXXXXXEPITSTIAVYRANPLGI---DYCQFREVAL-SNSTVQPLLNS---TSVGNSS 486
                   + +  T+ ++     G    DY   R  +L S S +   LN+   T++  S 
Sbjct: 497 FISITFVLDAVKGTVKIFWKYYYGHYLDDYHTKRTSSLVSLSGLGASLNASLHTALNASF 556

Query: 487 VVAPAPPVSRLPPQPNTALFCTMLTLATFVLAYYLRIFRNGKFLGRSSATSRVQVTGRDG 546
           + +P    S       TA+   ++ L T  L Y L  F+   +L                
Sbjct: 557 LASPTELPSATHSGQATAVLSLLIMLGTLWLGYTLYQFKKSPYLHPC------------- 603

Query: 547 IQARRALGDFGVPIAIVLMVGISCLVPVKTETLVVPAGLNPTTVRSWFVPLNPGLETIXX 606
              R  L D  +PIA++    IS     + E  +     NP+   S F      ++++  
Sbjct: 604 --VREILSDCALPIAVLAFSLISSHGFREIE--MSKFRYNPS--ESPFAMAQ--IQSLSL 655

Query: 607 XXXXXXXXXXXXVYIIVFMETHIAELIIAKPERRLKKGSGFHMDIVIMSFVNALCGMFGA 666
                       + ++ F+E ++   ++  PE RL KG+ +H D+++++ +N    +FG 
Sbjct: 656 RAVSGAMGLGFLLSMLFFIEQNLVAALVNAPENRLVKGTAYHWDLLLLAIINTGLSLFGL 715

Query: 667 PWQCVATVRSVSHVSALTIMSTTHAPGD-KPHIVEVKEQRLTGLLVAVMVGISVLASGW- 724
           PW   A   S  HV AL ++      G     IV VKE RLT L  +V+VG+S+L     
Sbjct: 716 PWIHAAYPHSPLHVRALALVEERVENGHIYDTIVNVKETRLTSLGASVLVGLSLLLLPVP 775

Query: 725 LCLVPMAVLFGVFLYMGISALGGIQFWDRCILLLKPVKHHPQLPYVRRVPTLKMHMYTLI 784
           L  +P  V +G+FLY+ +++L G Q   R  LLLK    +P   Y+RRVP  K+H +T +
Sbjct: 776 LQWIPKPVRYGLFLYIALTSLDGNQLVQRVALLLKEQTAYPPTHYIRRVPQRKIHYFTGL 835

Query: 785 QVGGVVVLYAVKSSR---FSLALPFFLVLMVPLRMSLV 819
           QV  +++L A   S      +  P  ++ M+P+R  L+
Sbjct: 836 QVLQLLLLCAFGMSSLPYMKMIFPLIMIAMIPIRYILL 873


>BC110541-1|AAI10542.1|  409|Homo sapiens SLC4A11 protein protein.
          Length = 409

 Score =  124 bits (300), Expect = 1e-27
 Identities = 71/204 (34%), Positives = 114/204 (55%), Gaps = 5/204 (2%)

Query: 621 IIVFMETHIAELIIAKPERRLKKGSGFHMDIVIMSFVNALCGMFGAPWQCVATVRSVSHV 680
           ++ F+E ++   ++  PE RL KG+ +H D+++++ +N    +FG PW   A   S  HV
Sbjct: 188 MLFFIEQNLVAALVNAPENRLVKGTAYHWDLLLLAIINTGLSLFGLPWIHAAYPHSPLHV 247

Query: 681 SALTIMSTTHAPGD-KPHIVEVKEQRLTGLLVAVMVGISVLASGW-LCLVPMAVLFGVFL 738
            AL ++      G     IV VKE RLT L  +V+VG+S+L     L  +P  VL+G+FL
Sbjct: 248 RALALVEERVENGHIYDTIVNVKETRLTSLGASVLVGLSLLLLPVPLQWIPKPVLYGLFL 307

Query: 739 YMGISALGGIQFWDRCILLLKPVKHHPQLPYVRRVPTLKMHMYTLIQVGGVVVLYAVKSS 798
           Y+ +++L G Q   R  LLLK    +P   Y+RRVP  K+H +T +QV  +++L A   S
Sbjct: 308 YIALTSLDGNQLVQRVALLLKEQTAYPPTHYIRRVPQRKIHYFTGLQVLQLLLLCAFGMS 367

Query: 799 R---FSLALPFFLVLMVPLRMSLV 819
                 +  P  ++ M+P+R  L+
Sbjct: 368 SLPYMKMIFPLIMIAMIPIRYILL 391


>AK128321-1|BAC87383.1|  329|Homo sapiens ember 8 (SLC4A8).
           protein.
          Length = 329

 Score = 95.9 bits (228), Expect = 5e-19
 Identities = 41/76 (53%), Positives = 58/76 (76%)

Query: 93  LKRIPDDAEATTVLVGAVGFLDQPTIAFVRLAEGIYMPSITEVPVPVRFMFILLGPGGAD 152
           +K+IP  AEA+ VLVG V  LD+P +AFVRL+  + +  +TEVP+P RF+FILLGP G  
Sbjct: 238 MKKIPTGAEASNVLVGEVDILDRPIVAFVRLSPAVLLSGLTEVPIPTRFLFILLGPVGKG 297

Query: 153 LDYHEVGRSISTLMSN 168
             YHE+GRS++T+M++
Sbjct: 298 QQYHEIGRSMATIMTD 313


>AC103915-1|AAY14938.1|   80|Homo sapiens unknown protein.
          Length = 80

 Score = 83.8 bits (198), Expect = 2e-15
 Identities = 35/64 (54%), Positives = 50/64 (78%)

Query: 141 FMFILLGPGGADLDYHEVGRSISTLMSNPAFHSIAYKADDRRELLSAINEFLDDSIVLPP 200
           F+FILLGP G    Y+E+GR+I+TLM +  F  +AYKA +R +L++ I+EFLD+ IVLPP
Sbjct: 1   FLFILLGPSGRAKSYNEIGRAIATLMVDDLFSDVAYKARNREDLIAGIDEFLDEVIVLPP 60

Query: 201 GDWE 204
           G+W+
Sbjct: 61  GEWD 64


>AC006030-1|AAF03523.2|  341|Homo sapiens unknown protein.
          Length = 341

 Score = 64.1 bits (149), Expect = 2e-09
 Identities = 35/71 (49%), Positives = 46/71 (64%), Gaps = 6/71 (8%)

Query: 74  LAHA-SESQDELRRTHN-----DSILKRIPDDAEATTVLVGAVGFLDQPTIAFVRLAEGI 127
           L HA S S +++  T N     +  +K+IP D+EA+ VLVG V FLDQP IAFVRL +  
Sbjct: 270 LCHAQSRSMNDISLTPNTDQRKNKFMKKIPKDSEASNVLVGEVDFLDQPFIAFVRLIQSA 329

Query: 128 YMPSITEVPVP 138
            +  +TEVPVP
Sbjct: 330 MLGGVTEVPVP 340


>AF226050-1|AAF86950.1|  319|Homo sapiens HCDI protein.
          Length = 319

 Score = 32.7 bits (71), Expect = 5.7
 Identities = 28/99 (28%), Positives = 43/99 (43%), Gaps = 3/99 (3%)

Query: 37  AACRRHSVALLNLSERRRRSTHARPSAAGLDPREVEYLAHASESQDELRRTHNDSILKRI 96
           A C+RH V L++      R T    +A+GL   +           + LRR +     + +
Sbjct: 46  AECQRHEVTLVSRKPGPGRITWDELAASGLPSCDAAVNLAGENILNPLRRWNETFQKEVL 105

Query: 97  PDDAEATTVLVGAVGFLDQPTIAFVRLAEGI--YMPSIT 133
               E T +L  A+    QP  A+V L  G+  Y PS+T
Sbjct: 106 GSRLETTQLLAKAITKAPQPPKAWV-LVTGVAYYQPSLT 143


>BC017710-1|AAH17710.1|  423|Homo sapiens zinc finger protein 271
           protein.
          Length = 423

 Score = 32.3 bits (70), Expect = 7.5
 Identities = 14/37 (37%), Positives = 21/37 (56%)

Query: 667 PWQCVATVRSVSHVSALTIMSTTHAPGDKPHIVEVKE 703
           P+QCV   RS S +S LTI    H   D  +++ V++
Sbjct: 361 PYQCVQCSRSCSQLSELTIHEEVHCGEDSQNVMNVRK 397


>BC004510-1|AAH04510.2|  272|Homo sapiens ZNF271 protein protein.
          Length = 272

 Score = 32.3 bits (70), Expect = 7.5
 Identities = 14/37 (37%), Positives = 21/37 (56%)

Query: 667 PWQCVATVRSVSHVSALTIMSTTHAPGDKPHIVEVKE 703
           P+QCV   RS S +S LTI    H   D  +++ V++
Sbjct: 210 PYQCVQCSRSCSQLSELTIHEEVHCGEDSQNVMNVRK 246


>AF159567-1|AAD43569.1|  423|Homo sapiens epstein-barr virus-induced
           zinc finger protein protein.
          Length = 423

 Score = 32.3 bits (70), Expect = 7.5
 Identities = 14/37 (37%), Positives = 21/37 (56%)

Query: 667 PWQCVATVRSVSHVSALTIMSTTHAPGDKPHIVEVKE 703
           P+QCV   RS S +S LTI    H   D  +++ V++
Sbjct: 361 PYQCVQCSRSCSQLSELTIHEEVHCGEDSQNVMNVRK 397


>AF153201-1|AAD38056.1|  423|Homo sapiens zinc finger protein dp
           protein.
          Length = 423

 Score = 32.3 bits (70), Expect = 7.5
 Identities = 14/37 (37%), Positives = 21/37 (56%)

Query: 667 PWQCVATVRSVSHVSALTIMSTTHAPGDKPHIVEVKE 703
           P+QCV   RS S +S LTI    H   D  +++ V++
Sbjct: 361 PYQCVQCSRSCSQLSELTIHEEVHCGEDSQNVMNVRK 397


>BC104759-1|AAI04760.1|  571|Homo sapiens ZNF181 protein protein.
          Length = 571

 Score = 31.9 bits (69), Expect = 9.9
 Identities = 13/31 (41%), Positives = 22/31 (70%), Gaps = 1/31 (3%)

Query: 667 PWQCVATVRSVSHVSALTIMSTTHAPGDKPH 697
           P++C+   ++ SHVS+LT   +TH  G+KP+
Sbjct: 292 PYKCIECGKAFSHVSSLTNHQSTHT-GEKPY 321


>BC043228-1|AAH43228.1|  507|Homo sapiens zinc finger protein 181
           protein.
          Length = 507

 Score = 31.9 bits (69), Expect = 9.9
 Identities = 13/31 (41%), Positives = 22/31 (70%), Gaps = 1/31 (3%)

Query: 667 PWQCVATVRSVSHVSALTIMSTTHAPGDKPH 697
           P++C+   ++ SHVS+LT   +TH  G+KP+
Sbjct: 228 PYKCIECGKAFSHVSSLTNHQSTHT-GEKPY 257


  Database: human
    Posted date:  Oct 5, 2007 11:13 AM
  Number of letters in database: 73,234,838
  Number of sequences in database:  224,733
  
Lambda     K      H
   0.324    0.138    0.414 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 119,973,246
Number of Sequences: 224733
Number of extensions: 4795204
Number of successful extensions: 14914
Number of sequences better than 10.0: 81
Number of HSP's better than 10.0 without gapping: 78
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 14518
Number of HSP's gapped (non-prelim): 167
length of query: 853
length of database: 73,234,838
effective HSP length: 96
effective length of query: 757
effective length of database: 51,660,470
effective search space: 39106975790
effective search space used: 39106975790
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 40 (21.5 bits)
S2: 69 (31.9 bits)