Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA002071-TA|BGIBMGA002071-PA|IPR002698|5-
formyltetrahydrofolate cyclo-ligase
(196 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI0000D569A3 Cluster: PREDICTED: similar to 5-formylte... 176 2e-43
UniRef50_P49914 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 165 8e-40
UniRef50_A7SFC3 Cluster: Predicted protein; n=1; Nematostella ve... 153 2e-36
UniRef50_P80405 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 148 1e-34
UniRef50_Q9XWE6 Cluster: Putative 5-formyltetrahydrofolate cyclo... 137 2e-31
UniRef50_Q16S54 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 134 2e-30
UniRef50_Q9W1R6 Cluster: CG11079-PA, isoform A; n=6; Diptera|Rep... 130 2e-29
UniRef50_UPI0000E47106 Cluster: PREDICTED: hypothetical protein;... 122 4e-27
UniRef50_Q4AQ84 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 100 3e-20
UniRef50_Q18VM6 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 99 8e-20
UniRef50_A6LQ49 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 99 8e-20
UniRef50_Q97K31 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 98 1e-19
UniRef50_A3LUI4 Cluster: 5,10-methenyltetrahydrofolate synthetas... 97 2e-19
UniRef50_A5Z6A8 Cluster: Putative uncharacterized protein; n=1; ... 97 2e-19
UniRef50_Q3AE50 Cluster: 5-formyltetrahydrofolate cyclo-ligase f... 96 4e-19
UniRef50_A5DWB9 Cluster: Putative uncharacterized protein; n=1; ... 96 4e-19
UniRef50_A5DQN3 Cluster: Putative uncharacterized protein; n=1; ... 96 6e-19
UniRef50_Q9KD02 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 93 3e-18
UniRef50_Q1AWE3 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 93 3e-18
UniRef50_Q65HC6 Cluster: YqgN; n=1; Bacillus licheniformis ATCC ... 93 4e-18
UniRef50_Q83F82 Cluster: 5-formyltetrahydrofolate cyclo-ligase f... 92 7e-18
UniRef50_A3IGL7 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 92 7e-18
UniRef50_Q97NE8 Cluster: 5-formyltetrahydrofolate cyclo-ligase f... 92 9e-18
UniRef50_A5N8A1 Cluster: 5-formyltetrahydrofolate cyclo-ligase-r... 91 1e-17
UniRef50_Q7MTT7 Cluster: 5-formyltetrahydrofolate cyclo-ligase f... 90 3e-17
UniRef50_A0L5J2 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 90 4e-17
UniRef50_Q896J3 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 89 6e-17
UniRef50_A6TVJ5 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 89 9e-17
UniRef50_A1SSJ1 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 89 9e-17
UniRef50_Q6CAN2 Cluster: Similar to sp|P40099 Saccharomyces cere... 88 1e-16
UniRef50_Q2RGK7 Cluster: 5-formyltetrahydrofolate cyclo-ligase p... 87 2e-16
UniRef50_Q7URX2 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 86 6e-16
UniRef50_Q03Y24 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 85 8e-16
UniRef50_Q5WH98 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 85 1e-15
UniRef50_Q41FV0 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 84 2e-15
UniRef50_A5VKU2 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 84 2e-15
UniRef50_A3DEZ8 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 84 2e-15
UniRef50_A4SLF4 Cluster: 5-formyltetrahydrofolate cyclo-ligase f... 83 3e-15
UniRef50_A6VM34 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 83 6e-15
UniRef50_Q72F49 Cluster: 5-formyltetrahydrofolate cyclo-ligase f... 82 7e-15
UniRef50_Q2ADA7 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 81 1e-14
UniRef50_P0AC29 Cluster: Uncharacterized protein ygfA; n=23; Ent... 81 1e-14
UniRef50_Q0SQM2 Cluster: 5-formyltetrahydrofolate cyclo-ligase f... 81 2e-14
UniRef50_A6CNU5 Cluster: Possible 5-formyltetrahydrofolate cyclo... 81 2e-14
UniRef50_A4J8I3 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 81 2e-14
UniRef50_A1WW94 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 81 2e-14
UniRef50_A7I701 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 81 2e-14
UniRef50_Q6CX89 Cluster: Similarities with sp|P40099 Saccharomyc... 80 3e-14
UniRef50_Q603N0 Cluster: 5-formyltetrahydrofolate cyclo-ligase f... 80 4e-14
UniRef50_Q6AQJ8 Cluster: Probable 5-formyltetrahydrofolate cyclo... 79 7e-14
UniRef50_A4WE63 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 79 7e-14
UniRef50_Q3AS61 Cluster: 5-formyltetrahydrofolate cyclo-ligase, ... 78 1e-13
UniRef50_A3EWC9 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 78 1e-13
UniRef50_Q3XWC2 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 77 2e-13
UniRef50_Q1WUH7 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 77 2e-13
UniRef50_A5KR22 Cluster: Putative uncharacterized protein; n=1; ... 77 2e-13
UniRef50_Q9FYA5 Cluster: 5-formyltetrahydrofolate cyclo-ligase-l... 77 2e-13
UniRef50_Q81LX0 Cluster: 5-formyltetrahydrofolate cyclo-ligase f... 77 3e-13
UniRef50_A1IE08 Cluster: 5-formyltetrahydrofolate cyclo-ligase f... 77 3e-13
UniRef50_Q67Q66 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 77 4e-13
UniRef50_P44905 Cluster: Uncharacterized protein HI0858; n=16; G... 77 4e-13
UniRef50_Q0HZ35 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 76 5e-13
UniRef50_Q1YVJ4 Cluster: 5-formyltetrahydrofolate cyclo-ligase f... 76 6e-13
UniRef50_Q011H2 Cluster: Predicted methyltransferase; n=2; Ostre... 76 6e-13
UniRef50_Q8RF22 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 75 9e-13
UniRef50_Q74E28 Cluster: 5-formyltetrahydrofolate cyclo-ligase f... 75 9e-13
UniRef50_Q4K404 Cluster: 5-formyltetrahydrofolate cyclo-ligase f... 75 9e-13
UniRef50_A6BE49 Cluster: Putative uncharacterized protein; n=1; ... 75 9e-13
UniRef50_Q5KX52 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 75 1e-12
UniRef50_Q3SFD5 Cluster: 5-formyltetrahydrofolate cyclo-ligase f... 75 1e-12
UniRef50_Q0VL96 Cluster: 5-formyltetrahydrofolate cyclo-ligase f... 75 1e-12
UniRef50_Q55ZD6 Cluster: Putative uncharacterized protein; n=1; ... 75 1e-12
UniRef50_A6NRP0 Cluster: Putative uncharacterized protein; n=1; ... 74 2e-12
UniRef50_Q0KWG0 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 74 3e-12
UniRef50_A6L8H7 Cluster: Putative 5-formyltetrahydrofolate cyclo... 74 3e-12
UniRef50_Q8DC92 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 73 3e-12
UniRef50_Q5HNZ9 Cluster: 5-formyltetrahydrofolate cyclo-ligase f... 73 3e-12
UniRef50_Q180V5 Cluster: Putative 5-formyltetrahydrofolate cyclo... 73 5e-12
UniRef50_A6QH93 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 73 5e-12
UniRef50_A0W837 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 73 5e-12
UniRef50_P54491 Cluster: Uncharacterized protein yqgN; n=2; Baci... 72 8e-12
UniRef50_Q2B5W6 Cluster: Possible 5-formyltetrahydrofolate cyclo... 72 1e-11
UniRef50_A7H9A8 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 72 1e-11
UniRef50_Q1MZK4 Cluster: 5-formyltetrahydrofolate cyclo-ligase f... 71 1e-11
UniRef50_A6EYV6 Cluster: 5-formyltetrahydrofolate cyclo-ligase f... 71 1e-11
UniRef50_Q89ZW3 Cluster: Putative 5-formyltetrahydrofolate cyclo... 71 2e-11
UniRef50_Q7P0R7 Cluster: Probable 5-formyltetrahydrofolate cyclo... 71 2e-11
UniRef50_Q03RP0 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 71 2e-11
UniRef50_A2U6F2 Cluster: 5-formyltetrahydrofolate cyclo-ligase p... 71 2e-11
UniRef50_Q9P7W2 Cluster: Putative 5-formyltetrahydrofolate cyclo... 71 2e-11
UniRef50_A0V3Q2 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 71 2e-11
UniRef50_Q21EV7 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 70 3e-11
UniRef50_Q08SB2 Cluster: 5,10-methenyltetrahydrofolate synthetas... 70 3e-11
UniRef50_A7DEJ5 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 70 3e-11
UniRef50_A7B2U8 Cluster: Putative uncharacterized protein; n=1; ... 70 3e-11
UniRef50_A1S972 Cluster: 5-formyltetrahydrofolate cyclo-ligase f... 70 3e-11
UniRef50_UPI0000DAE4A8 Cluster: hypothetical protein Rgryl_01000... 70 4e-11
UniRef50_Q14L13 Cluster: Putative 5-formyltetrahydrofolate cyclo... 70 4e-11
UniRef50_Q0A5K9 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 70 4e-11
UniRef50_A4A119 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 70 4e-11
UniRef50_A0NJT9 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 70 4e-11
UniRef50_Q4P9A6 Cluster: Putative uncharacterized protein; n=1; ... 70 4e-11
UniRef50_O67621 Cluster: Putative uncharacterized protein; n=1; ... 69 6e-11
UniRef50_Q2BL70 Cluster: Putative uncharacterized protein; n=1; ... 69 6e-11
UniRef50_Q041X5 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 69 6e-11
UniRef50_Q1JZM9 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 69 7e-11
UniRef50_A1HT82 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 69 7e-11
UniRef50_Q0YQW9 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 69 1e-10
UniRef50_Q049I2 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 69 1e-10
UniRef50_Q31FB9 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 68 1e-10
UniRef50_A5ZYS6 Cluster: Putative uncharacterized protein; n=3; ... 68 1e-10
UniRef50_A4B9S4 Cluster: Putative carbon-nitrogen ligase; n=1; R... 68 1e-10
UniRef50_Q0ALV8 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 68 2e-10
UniRef50_Q03G82 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 68 2e-10
UniRef50_A1U687 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 68 2e-10
UniRef50_Q3A217 Cluster: Putative ligase; n=1; Pelobacter carbin... 67 2e-10
UniRef50_Q1FEZ7 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 67 2e-10
UniRef50_A7HUZ2 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 67 2e-10
UniRef50_A4XKH5 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 67 2e-10
UniRef50_A3CVT9 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 67 2e-10
UniRef50_A4E9T0 Cluster: Putative uncharacterized protein; n=1; ... 66 4e-10
UniRef50_A3MYI1 Cluster: Putative uncharacterized protein; n=1; ... 66 5e-10
UniRef50_P40099 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 66 5e-10
UniRef50_Q0YHK3 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 66 7e-10
UniRef50_A4BS87 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 66 7e-10
UniRef50_A4ABX0 Cluster: 5-formyltetrahydrofolate cyclo-ligase f... 66 7e-10
UniRef50_Q1DNE6 Cluster: Putative uncharacterized protein; n=2; ... 66 7e-10
UniRef50_Q88WQ3 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 65 9e-10
UniRef50_Q44SK2 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 65 9e-10
UniRef50_A6VUD0 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 65 9e-10
UniRef50_Q6FTS7 Cluster: Similar to sp|P40099 Saccharomyces cere... 65 9e-10
UniRef50_A7DNA8 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 65 9e-10
UniRef50_Q38VZ7 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 65 1e-09
UniRef50_A7IJU7 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 65 1e-09
UniRef50_A5P2B9 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 65 1e-09
UniRef50_A4B8C7 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 65 1e-09
UniRef50_A0Y9S2 Cluster: 5-formyltetrahydrofolate cyclo-ligase f... 65 1e-09
UniRef50_Q8G439 Cluster: Putative uncharacterized protein; n=1; ... 64 2e-09
UniRef50_Q830J1 Cluster: 5-formyltetrahydrofolate cyclo-ligase f... 64 2e-09
UniRef50_Q8Y7E7 Cluster: Lmo1336 protein; n=13; Listeria|Rep: Lm... 64 2e-09
UniRef50_Q5ZXY7 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 64 2e-09
UniRef50_A1BG38 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 64 2e-09
UniRef50_A6S3W0 Cluster: Putative uncharacterized protein; n=5; ... 64 2e-09
UniRef50_A1CDT2 Cluster: 5-formyltetrahydrofolate cyclo-ligase, ... 64 2e-09
UniRef50_Q5FIZ8 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 63 4e-09
UniRef50_Q1MQA3 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 63 4e-09
UniRef50_A4AI88 Cluster: 5-formyltetrahydrofolate cyclo-ligase-r... 63 4e-09
UniRef50_A1KWH4 Cluster: Putative uncharacterized protein; n=4; ... 63 4e-09
UniRef50_A2SSS2 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 63 4e-09
UniRef50_Q7VRG0 Cluster: Ligase;5-formyltetrahydrofolate cycloli... 63 5e-09
UniRef50_A7JX05 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 63 5e-09
UniRef50_A4SEK3 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 63 5e-09
UniRef50_Q03UF8 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 62 8e-09
UniRef50_A3VP85 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 62 8e-09
UniRef50_Q8NS05 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 62 1e-08
UniRef50_A6G5C7 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 62 1e-08
UniRef50_Q89AD6 Cluster: Uncharacterized protein bbp_370; n=1; B... 62 1e-08
UniRef50_Q5QVB4 Cluster: 5-formyltetrahydrofolate cyclo-ligase f... 61 1e-08
UniRef50_Q8K9E3 Cluster: Uncharacterized protein BUsg_396; n=1; ... 61 1e-08
UniRef50_Q8EQ05 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 61 2e-08
UniRef50_A2RHQ0 Cluster: 5-formyltetrahydrofolate cyclo-ligase f... 61 2e-08
UniRef50_Q2SN29 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 60 3e-08
UniRef50_Q3VT50 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 60 3e-08
UniRef50_Q1V201 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 60 3e-08
UniRef50_A1AXM1 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 60 3e-08
UniRef50_A5IZ16 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 60 3e-08
UniRef50_A0RTU2 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 60 3e-08
UniRef50_UPI0000E0F49C Cluster: hypothetical 5-formyltetrahydrof... 60 5e-08
UniRef50_Q1LSJ3 Cluster: 5-formyltetrahydrofolate cyclo-ligase f... 59 6e-08
UniRef50_Q47T07 Cluster: Putative uncharacterized protein; n=1; ... 59 8e-08
UniRef50_Q2NB11 Cluster: Possible 5-formyltetrahydrofolate cyclo... 59 8e-08
UniRef50_A5CYV1 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 59 8e-08
UniRef50_Q40JH2 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 58 1e-07
UniRef50_Q3DVF9 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 58 1e-07
UniRef50_Q73P08 Cluster: 5-formyltetrahydrofolate cyclo-ligase f... 58 2e-07
UniRef50_Q5PAS2 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 58 2e-07
UniRef50_Q57BF7 Cluster: 5-formyltetrahydrofolate cyclo-ligase f... 58 2e-07
UniRef50_O83692 Cluster: 5,10-methenyltetrahydrofolate synthetas... 58 2e-07
UniRef50_A6PRD6 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 58 2e-07
UniRef50_Q2FMV3 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 58 2e-07
UniRef50_Q9A3F9 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 57 2e-07
UniRef50_Q7NBA0 Cluster: Putative uncharacterized protein; n=1; ... 57 3e-07
UniRef50_Q9F7S8 Cluster: Predicted 5-formyltetrahydrofolate cycl... 57 3e-07
UniRef50_A4CIN4 Cluster: Putative uncharacterized protein; n=1; ... 57 3e-07
UniRef50_UPI0001553191 Cluster: PREDICTED: hypothetical protein;... 56 4e-07
UniRef50_Q6N1F2 Cluster: Antifreeze protein, type I:5-formyltetr... 56 4e-07
UniRef50_O68985 Cluster: Putative uncharacterized protein; n=1; ... 56 4e-07
UniRef50_Q1NDJ9 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 56 4e-07
UniRef50_UPI0000384628 Cluster: COG0212: 5-formyltetrahydrofolat... 56 6e-07
UniRef50_Q7NMK6 Cluster: Glr0759 protein; n=1; Gloeobacter viola... 56 6e-07
UniRef50_Q31NN9 Cluster: Putative uncharacterized protein; n=2; ... 56 6e-07
UniRef50_Q0EWY4 Cluster: 5-formyltetrahydrofolate cyclo-ligase f... 56 6e-07
UniRef50_A6RBY2 Cluster: Predicted protein; n=1; Ajellomyces cap... 56 6e-07
UniRef50_Q11X92 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 56 7e-07
UniRef50_A3K0D8 Cluster: 5-formyltetrahydrofolate cyclo-ligase f... 56 7e-07
UniRef50_P73038 Cluster: Sll1643 protein; n=1; Synechocystis sp.... 55 1e-06
UniRef50_Q1GFD0 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 55 1e-06
UniRef50_A1A037 Cluster: Putative uncharacterized protein; n=2; ... 55 1e-06
UniRef50_Q8DK86 Cluster: Tll0980 protein; n=1; Synechococcus elo... 55 1e-06
UniRef50_Q0F944 Cluster: Putative 5-formyltetrahydrofolate cyclo... 55 1e-06
UniRef50_Q0AVU2 Cluster: 5-formyltetrahydrofolate cyclo-ligase f... 55 1e-06
UniRef50_A3V9L4 Cluster: 5-formyltetrahydrofolate cyclo-ligase f... 55 1e-06
UniRef50_A0JYX4 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 55 1e-06
UniRef50_Q0RC09 Cluster: Putative ligase; n=1; Frankia alni ACN1... 54 2e-06
UniRef50_A1SES9 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 54 2e-06
UniRef50_A1FY99 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 54 2e-06
UniRef50_Q2J5Q1 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 54 2e-06
UniRef50_Q1NVQ1 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 54 2e-06
UniRef50_A4F7U0 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 54 2e-06
UniRef50_Q6SHV0 Cluster: 5-formyltetrahydrofolate cyclo-ligase f... 54 3e-06
UniRef50_Q15Q29 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 54 3e-06
UniRef50_Q8YMV1 Cluster: All4825 protein; n=8; Cyanobacteria|Rep... 53 4e-06
UniRef50_A6EDM4 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 53 4e-06
UniRef50_A6DB91 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 53 4e-06
UniRef50_A4TWG6 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 53 4e-06
UniRef50_A1URD6 Cluster: 5,10-methenyltetrahydrofolate synthetas... 53 4e-06
UniRef50_Q2JU73 Cluster: 5-formyltetrahydrofolate cyclo-ligase f... 53 5e-06
UniRef50_UPI00006CBD0D Cluster: 5-formyltetrahydrofolate cyclo-l... 52 7e-06
UniRef50_Q82Y32 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 52 7e-06
UniRef50_Q03B49 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 52 7e-06
UniRef50_Q6F1L6 Cluster: 5-formyltetrahydrofolate cyclo-ligase f... 52 9e-06
UniRef50_Q6AAH0 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 52 9e-06
UniRef50_Q5FUD7 Cluster: 5-Formyltetrahydrofolate cyclo-ligase; ... 52 9e-06
UniRef50_Q83FP9 Cluster: Putative uncharacterized protein; n=2; ... 52 1e-05
UniRef50_Q2S230 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 52 1e-05
UniRef50_Q0BZ02 Cluster: 5-formyltetrahydrofolate cyclo-ligase f... 51 2e-05
UniRef50_A5EXF0 Cluster: 5-formyltetrahydrofolate cyclo-ligase f... 51 2e-05
UniRef50_A1B1U2 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 51 2e-05
UniRef50_Q5SHW9 Cluster: 5-formyltetrahydrofolate cyclo-ligase f... 51 2e-05
UniRef50_Q3B454 Cluster: 5-formyltetrahydrofolate cyclo-ligase, ... 51 2e-05
UniRef50_A6DHI6 Cluster: Putative uncharacterized protein; n=1; ... 51 2e-05
UniRef50_A3UGX7 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 51 2e-05
UniRef50_Q75BE9 Cluster: ADL385Cp; n=1; Eremothecium gossypii|Re... 50 3e-05
UniRef50_Q4FR52 Cluster: Possible 5-formyltetrahydrofolate cyclo... 50 4e-05
UniRef50_A0LR79 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 50 4e-05
UniRef50_UPI000050F91E Cluster: COG0212: 5-formyltetrahydrofolat... 50 5e-05
UniRef50_Q6NIB6 Cluster: Putative uncharacterized protein; n=1; ... 50 5e-05
UniRef50_Q4E7I6 Cluster: Protein; n=5; Wolbachia|Rep: Protein - ... 49 6e-05
UniRef50_Q1GTI6 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 49 6e-05
UniRef50_A5CEL8 Cluster: 5-Formyltetrahydrofolate cyclo-ligase; ... 49 6e-05
UniRef50_A0NNE7 Cluster: Putative uncharacterized protein; n=1; ... 49 6e-05
UniRef50_Q89U90 Cluster: Blr1527 protein; n=1; Bradyrhizobium ja... 49 8e-05
UniRef50_Q477X4 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 49 8e-05
UniRef50_A7B9R4 Cluster: Putative uncharacterized protein; n=1; ... 49 8e-05
UniRef50_A2U3L0 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 49 8e-05
UniRef50_Q1IX36 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 48 1e-04
UniRef50_UPI0000E87FAB Cluster: 5-formyltetrahydrofolate cyclo-l... 48 1e-04
UniRef50_Q6FD61 Cluster: Putative ligase; n=3; Acinetobacter|Rep... 48 1e-04
UniRef50_A5V9J0 Cluster: 5-formyltetrahydrofolate cyclo-ligase p... 48 1e-04
UniRef50_Q2G6W2 Cluster: 5-formyltetrahydrofolate cyclo-ligase p... 48 2e-04
UniRef50_Q3AZ02 Cluster: Putative uncharacterized protein; n=2; ... 47 3e-04
UniRef50_O26306 Cluster: Conserved protein; n=1; Methanothermoba... 47 3e-04
UniRef50_A3J2X7 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 47 3e-04
UniRef50_Q30SA8 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 46 5e-04
UniRef50_A6UKG2 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 46 5e-04
UniRef50_A2BIS5 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 46 5e-04
UniRef50_Q2RVG0 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 46 6e-04
UniRef50_Q2CK01 Cluster: Putative uncharacterized protein; n=6; ... 46 6e-04
UniRef50_Q4D2J6 Cluster: Putative uncharacterized protein; n=2; ... 46 6e-04
UniRef50_Q9Z7E3 Cluster: Formyltetrahydrofolate Cycloligase; n=4... 46 8e-04
UniRef50_Q92HS7 Cluster: Similarity to 5-formyltetrahydrofolate ... 46 8e-04
UniRef50_Q7VIL6 Cluster: Putative uncharacterized protein; n=1; ... 46 8e-04
UniRef50_Q7D907 Cluster: 5-formyltetrahydrofolate cyclo-ligase-r... 46 8e-04
UniRef50_Q6MNQ4 Cluster: InterPro: 5-formyltetrahydrofolate cycl... 45 0.001
UniRef50_Q6J6A2 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 45 0.001
UniRef50_Q1VME8 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 45 0.001
UniRef50_A5GM63 Cluster: Putative uncharacterized protein SynWH7... 45 0.001
UniRef50_A1ZJP2 Cluster: 5,10-methenyltetrahydrofolate synthetas... 45 0.001
UniRef50_Q1VH78 Cluster: Probable 5-formyltetrahydrofolate cyclo... 45 0.001
UniRef50_Q4JBH0 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 45 0.001
UniRef50_UPI0000DB6C87 Cluster: PREDICTED: similar to CG14648-PA... 44 0.002
UniRef50_Q7W1Z1 Cluster: 5-formyltetrahydrofolate cyclo-ligase f... 44 0.002
UniRef50_A7GY22 Cluster: 5,10-methenyltetrahydrofolate synthetas... 44 0.002
UniRef50_A3YY34 Cluster: Putative uncharacterized protein; n=1; ... 44 0.002
UniRef50_Q2H2V3 Cluster: Putative uncharacterized protein; n=1; ... 44 0.002
UniRef50_A3U5R6 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 44 0.002
UniRef50_A1G3P7 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 44 0.002
UniRef50_Q57W74 Cluster: Putative uncharacterized protein; n=1; ... 44 0.002
UniRef50_Q4JU08 Cluster: Putative uncharacterized protein; n=1; ... 44 0.003
UniRef50_Q4QB50 Cluster: Putative uncharacterized protein; n=3; ... 44 0.003
UniRef50_Q4ULB4 Cluster: 5-Formyltetrahydrofolate cyclo-ligase; ... 43 0.004
UniRef50_A2C833 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 43 0.004
UniRef50_Q8I4Y1 Cluster: Putative uncharacterized protein; n=1; ... 43 0.006
UniRef50_UPI00015BCCCB Cluster: UPI00015BCCCB related cluster; n... 42 0.010
UniRef50_Q9KEL6 Cluster: BH0836 protein; n=1; Bacillus haloduran... 42 0.010
UniRef50_Q5NR15 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 42 0.010
UniRef50_Q0BT60 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 42 0.010
UniRef50_A6GU56 Cluster: Putative uncharacterized protein; n=1; ... 42 0.010
UniRef50_A4KQQ5 Cluster: 5-formyltetrahydroformate cycloligase; ... 42 0.010
UniRef50_Q39C40 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 42 0.013
UniRef50_A2SL05 Cluster: Putative uncharacterized protein; n=1; ... 42 0.013
UniRef50_Q2GER3 Cluster: 5,10-methenyltetrahydrofolate synthetas... 41 0.017
UniRef50_A0Z2P3 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 41 0.017
UniRef50_Q8TUZ6 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 41 0.017
UniRef50_Q46JY7 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 41 0.022
UniRef50_A3HW78 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 41 0.022
UniRef50_A1HAT0 Cluster: 5-formyltetrahydrofolate cyclo-ligase-l... 41 0.022
UniRef50_Q0P948 Cluster: Putative 5-formyltetrahydrofolate cyclo... 40 0.030
UniRef50_A6T2Y6 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 40 0.030
UniRef50_A7I2Y8 Cluster: 5,10-methenyltetrahydrofolate synthetas... 40 0.052
UniRef50_A7BS36 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 40 0.052
UniRef50_A3S249 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 40 0.052
UniRef50_Q9VN21 Cluster: CG14648-PA, isoform A; n=4; Sophophora|... 40 0.052
UniRef50_A0LFH5 Cluster: 5-formyltetrahydrofolate cyclo-ligase-l... 39 0.068
UniRef50_A0CQE5 Cluster: Chromosome undetermined scaffold_24, wh... 39 0.068
UniRef50_Q9PLS7 Cluster: 5-formyltetrahydrofolate cyclo-ligase, ... 39 0.090
UniRef50_A1BBF7 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 39 0.090
UniRef50_A0RNB2 Cluster: 5,10-methenyltetrahydrofolate synthetas... 39 0.090
UniRef50_Q0TWV8 Cluster: Predicted protein; n=1; Phaeosphaeria n... 39 0.090
UniRef50_A6WEB4 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 38 0.12
UniRef50_A4T0E7 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 38 0.12
UniRef50_Q98N02 Cluster: Mll0364 protein; n=4; Rhizobiales|Rep: ... 38 0.16
UniRef50_A2BRN1 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 38 0.16
UniRef50_Q17J32 Cluster: Putative uncharacterized protein; n=2; ... 38 0.16
UniRef50_Q2JBX8 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 38 0.21
UniRef50_Q12FT0 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 38 0.21
UniRef50_Q2M296 Cluster: Methenyltetrahydrofolate synthetase dom... 38 0.21
UniRef50_Q5UXE1 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 37 0.28
UniRef50_Q2KI24 Cluster: Methenyltetrahydrofolate synthetase dom... 37 0.28
UniRef50_A0NLR0 Cluster: Putative uncharacterized protein; n=1; ... 37 0.37
UniRef50_A5GRX1 Cluster: 5-formyltetrahydrofolate cyclo-ligase f... 36 0.48
UniRef50_A1K2Q9 Cluster: , complete genome; n=2; Azoarcus|Rep: ,... 36 0.48
UniRef50_Q7MSV4 Cluster: Putative uncharacterized protein; n=1; ... 36 0.64
UniRef50_Q0S4X5 Cluster: Putative uncharacterized protein; n=1; ... 36 0.64
UniRef50_A3TPS1 Cluster: Putative ligase; n=1; Janibacter sp. HT... 36 0.64
UniRef50_UPI00015B44D2 Cluster: PREDICTED: similar to RH35990p; ... 36 0.84
UniRef50_Q7VBE7 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 36 0.84
UniRef50_Q0IBL5 Cluster: 5-formyltetrahydrofolate cyclo-ligase f... 36 0.84
UniRef50_A6Q7U9 Cluster: Putative uncharacterized protein; n=1; ... 36 0.84
UniRef50_UPI00015B8B29 Cluster: UPI00015B8B29 related cluster; n... 35 1.1
UniRef50_UPI0000D56FA8 Cluster: PREDICTED: similar to CG14648-PA... 35 1.1
UniRef50_Q0V4P7 Cluster: Putative uncharacterized protein; n=1; ... 35 1.1
UniRef50_Q1LS15 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 35 1.5
UniRef50_A6X384 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 35 1.5
UniRef50_A4RB99 Cluster: Putative uncharacterized protein; n=2; ... 35 1.5
UniRef50_A7D5P9 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 35 1.5
UniRef50_P47487 Cluster: Uncharacterized protein MG245; n=2; Myc... 35 1.5
UniRef50_Q8F6Q4 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 33 4.5
UniRef50_A3U2I5 Cluster: Calcium binding hemolysin protein, puta... 33 4.5
UniRef50_Q88UD8 Cluster: ATP phosphoribosyltransferase regulator... 33 4.5
UniRef50_UPI00004990B3 Cluster: predicted protein; n=62; Entamoe... 33 5.9
UniRef50_Q8TY79 Cluster: Uncharacterized protein; n=1; Methanopy... 33 5.9
UniRef50_A1RWD1 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 33 5.9
UniRef50_Q1VSI9 Cluster: Deoxyribodipyrimidine photolyase-like p... 32 7.9
UniRef50_A6X380 Cluster: 5-formyltetrahydrofolate cyclo-ligase; ... 32 7.9
UniRef50_Q9LF59 Cluster: Glycine/proline-rich protein; n=12; Euk... 32 7.9
UniRef50_Q7PRT0 Cluster: ENSANGP00000019134; n=1; Anopheles gamb... 32 7.9
UniRef50_Q7Z6Z7 Cluster: E3 ubiquitin-protein ligase HUWE1; n=36... 32 7.9
>UniRef50_UPI0000D569A3 Cluster: PREDICTED: similar to
5-formyltetrahydrofolate cyclo-ligase
(5,10-methenyl-tetrahydrofolate synthetase)
(Methenyl-THF synthetase) (MTHFS); n=1; Tribolium
castaneum|Rep: PREDICTED: similar to
5-formyltetrahydrofolate cyclo-ligase
(5,10-methenyl-tetrahydrofolate synthetase)
(Methenyl-THF synthetase) (MTHFS) - Tribolium castaneum
Length = 197
Score = 176 bits (429), Expect = 2e-43
Identities = 84/191 (43%), Positives = 126/191 (65%), Gaps = 5/191 (2%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 69
K +R EI+ ++ LT+EEK+ QS+IV+EK++N ++ S R++ Y+S +NEIDT P+++
Sbjct: 8 KEAVRREISERLKHLTSEEKQTQSKIVFEKLLNLPSFQKSKRVSTYLSIDNEIDTEPIVR 67
Query: 70 HIQARGAAAFVPQY----AGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGG 125
I G FVP+Y AG M +H D +T+P T GI Q G + R+DAL+TGG
Sbjct: 68 KIFETGKECFVPRYRYSKAGMEMVKIH-SYQDWETLPVTSWGIKQPGLKEQREDALKTGG 126
Query: 126 LDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQ 185
LD ++ PGV F+ G RLGHGGGYYD+++ +LR N + P +V +AF Q+ D++P E
Sbjct: 127 LDFVVVPGVGFTAKGLRLGHGGGYYDRYMADLRKNQDVPPALVGLAFKEQICDDLPVTEL 186
Query: 186 DQKVDEVIFAE 196
D ++D V+F E
Sbjct: 187 DVQIDLVLFPE 197
>UniRef50_P49914 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=16; Euteleostomi|Rep: 5-formyltetrahydrofolate
cyclo-ligase - Homo sapiens (Human)
Length = 203
Score = 165 bits (400), Expect = 8e-40
Identities = 81/199 (40%), Positives = 125/199 (62%), Gaps = 3/199 (1%)
Query: 1 MSPIKPNPAKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTEN 60
M+ + AK LR E+ ++ A++ EE+ RQS+++ +KVI HS Y+ S RI++++S ++
Sbjct: 1 MAAAAVSSAKRSLRGELKQRLRAMSAEERLRQSRVLSQKVIAHSEYQKSKRISIFLSMQD 60
Query: 61 EIDTAPLIKHIQARGAAAFVPQYA--GGRMRMLHLETGDE-QTMPKTKHGISQHGKDQAR 117
EI+T +IK I RG F+P+Y M M+ +E+ +E +PKT I Q G+ R
Sbjct: 61 EIETEEIIKDIFQRGKICFIPRYRFQSNHMDMVRIESPEEISLLPKTSWNIPQPGEGDVR 120
Query: 118 DDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVV 177
++AL TGGLDLI PG+ F + G+RLG G GYYD ++ + E P +A+AF Q+
Sbjct: 121 EEALSTGGLDLIFMPGLGFDKHGNRLGRGKGYYDAYLKRCLQHQEVKPYTLALAFKEQIC 180
Query: 178 DEVPTNEQDQKVDEVIFAE 196
+VP NE D KVDEV++ +
Sbjct: 181 LQVPVNENDMKVDEVLYED 199
>UniRef50_A7SFC3 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 205
Score = 153 bits (372), Expect = 2e-36
Identities = 73/189 (38%), Positives = 116/189 (61%), Gaps = 1/189 (0%)
Query: 9 AKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLI 68
AK LLR +I +I A++ E K+++S ++ EK++ YKSS RI++Y+S +E+ T ++
Sbjct: 10 AKKLLRRQIKKRILAMSEEAKRKESAMITEKLLAMEEYKSSHRISVYLSMPSEVSTFDIL 69
Query: 69 KHIQARGAAAFVPQYAGGRMRMLHLET-GDEQTMPKTKHGISQHGKDQARDDALETGGLD 127
+ I ++P+Y G +M ML L + D Q++P T I Q D R++AL TGGLD
Sbjct: 70 RDIFNSNKKCYIPRYIGHQMDMLRLHSLEDMQSLPLTPWNIHQPADDDIREEALNTGGLD 129
Query: 128 LIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQ 187
+I+ PG+ FS++G RLG G GYYD +I P ++ +AF+ Q+ D+VP E D
Sbjct: 130 VILVPGLGFSKNGQRLGRGKGYYDNYIQKCIELCHKKPHLIGLAFSTQMYDQVPVTENDM 189
Query: 188 KVDEVIFAE 196
+D V+F +
Sbjct: 190 TLDHVVFCQ 198
>UniRef50_P80405 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=12; Euteleostomi|Rep: 5-formyltetrahydrofolate
cyclo-ligase - Oryctolagus cuniculus (Rabbit)
Length = 201
Score = 148 bits (358), Expect = 1e-34
Identities = 73/191 (38%), Positives = 115/191 (60%), Gaps = 3/191 (1%)
Query: 9 AKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLI 68
AK LR E+ ++ A++ EE+ R +++ +KVI H Y+ S RI++++S +EI+T +I
Sbjct: 9 AKRSLRAELKQRLRAISAEERLRCQRLLTQKVIAHRQYQKSQRISIFLSMPDEIETEEII 68
Query: 69 KHIQARGAAAFVPQYA--GGRMRMLHLETGDE-QTMPKTKHGISQHGKDQARDDALETGG 125
K I +G F+P+Y M M+ L + DE ++PKT I Q + R++AL TGG
Sbjct: 69 KDIFQQGKVCFIPRYRLQSNHMDMVKLASADEISSLPKTSWNIHQPSESDTREEALATGG 128
Query: 126 LDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQ 185
LDLI PG+ F R+G+RLG G GYYD ++ P +A+AF Q+ +VP ++
Sbjct: 129 LDLIFMPGLGFDRNGNRLGRGRGYYDTYLQRCLQQQGAKPYTIALAFREQICPQVPVDDT 188
Query: 186 DQKVDEVIFAE 196
D VDEV++ +
Sbjct: 189 DVSVDEVLYVD 199
>UniRef50_Q9XWE6 Cluster: Putative 5-formyltetrahydrofolate
cyclo-ligase; n=2; Caenorhabditis|Rep: Putative
5-formyltetrahydrofolate cyclo-ligase - Caenorhabditis
elegans
Length = 206
Score = 137 bits (331), Expect = 2e-31
Identities = 75/198 (37%), Positives = 112/198 (56%), Gaps = 6/198 (3%)
Query: 1 MSPIKPNPAKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTEN 60
MS IK K+ LR + + ++ EE +RQ++ V+EK+I W++ S R+++Y+ST
Sbjct: 1 MSAIKE--VKSELRQFMKTLLGKISKEETQRQTEAVFEKIIESKWFQESKRLSVYVSTSG 58
Query: 61 EIDTAPLIKHIQARGAAAFVPQYAGGRMRMLHLETGDE---QTMPKTKHGISQHGKDQAR 117
EI T +I+ G F+PQ+ G M + D+ +P T GI Q
Sbjct: 59 EIQTDSIIQKALEMGKEVFIPQFTKGSTAMDMVRVPDQTAFDNLPSTLWGIRQPEPKWKW 118
Query: 118 DDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFI-TNLRLNPETAPKIVAVAFNCQV 176
ETG LDLI+APGVAFS G R GHG GYYD+F T+ + PE +PK + +A Q+
Sbjct: 119 QSYHETGPLDLILAPGVAFSPYGLRCGHGKGYYDRFFSTHHKHFPENSPKKIGLALREQI 178
Query: 177 VDEVPTNEQDQKVDEVIF 194
+ +P +E D ++DEVI+
Sbjct: 179 IGTIPISETDVELDEVIY 196
>UniRef50_Q16S54 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=3; Culicidae|Rep: 5-formyltetrahydrofolate
cyclo-ligase - Aedes aegypti (Yellowfever mosquito)
Length = 208
Score = 134 bits (323), Expect = 2e-30
Identities = 78/199 (39%), Positives = 116/199 (58%), Gaps = 10/199 (5%)
Query: 7 NPAKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAP 66
NPAK LR ++ ++ +++ + QS+I+ KV +Y S RI +Y+STE E++T P
Sbjct: 6 NPAKVALRQQLKTVMSNMSSTARITQSKIIANKVQQLPFYHDSQRICIYLSTEREVNTVP 65
Query: 67 LIKHIQARGAAAFVPQYAGGRMRMLHL-ETGDEQTMPKTKHGISQ-HGKDQARDDALETG 124
L++ + R FVP Y MRM+ + + D +P T I Q + D +R+D L T
Sbjct: 66 LLQDMFHRSKEVFVPTYNRTAMRMVKINDMVDYDRLPTTSWNIKQPNFGDNSREDCLAT- 124
Query: 125 GLDLIIAPGVAFSRSGDRLGHGGGYYDKFITN-LRLNPETAPK----IVAVAFNCQVV-- 177
GLD+II PGV F+RSG RLGHGGGYYD+F+ + P + +V VAF Q+V
Sbjct: 125 GLDMIILPGVGFTRSGHRLGHGGGYYDRFLLEYFKKFPNASDNRKTYLVGVAFREQIVPE 184
Query: 178 DEVPTNEQDQKVDEVIFAE 196
D++P E D +D VI+ +
Sbjct: 185 DQLPIAEHDFPLDMVIWPD 203
>UniRef50_Q9W1R6 Cluster: CG11079-PA, isoform A; n=6; Diptera|Rep:
CG11079-PA, isoform A - Drosophila melanogaster (Fruit
fly)
Length = 318
Score = 130 bits (314), Expect = 2e-29
Identities = 71/192 (36%), Positives = 109/192 (56%), Gaps = 5/192 (2%)
Query: 7 NPAKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAP 66
N K LR + + + E RQSQ V KV+ ++ + R+++Y+ST +E+DT
Sbjct: 124 NTLKVALRKRMKDALKGIDAEAIARQSQAVTAKVLQSEIFRQAQRVSIYLSTASELDTTA 183
Query: 67 LIKHIQARGAAAFVPQYAGGRMRMLHLETGDE-QTMPKTKHGISQHGKDQARDDALETG- 124
L+ + FVP Y G RM+M+ L +E +++P TK I Q +AR+DA+ G
Sbjct: 184 LLSEMFRLEKMVFVPTYEGSRMKMVRLRGMEEYESLPLTKWNIKQPDFKEAREDAMTNGH 243
Query: 125 GLDLIIAPGVAFSRSGDRLGHGGGYYDKFI-TNLRLNPETAPKIVAVAFNCQVV--DEVP 181
G+DL I PGVAF+R G R+GHG GYYDKF+ + P ++A++ N Q+V +E+P
Sbjct: 244 GIDLFIVPGVAFTRCGARMGHGMGYYDKFLKQHAEKYPHKKISLMALSLNEQIVSNEELP 303
Query: 182 TNEQDQKVDEVI 193
D ++ VI
Sbjct: 304 MESHDVRLHSVI 315
>UniRef50_UPI0000E47106 Cluster: PREDICTED: hypothetical protein;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 161
Score = 122 bits (295), Expect = 4e-27
Identities = 58/158 (36%), Positives = 94/158 (59%), Gaps = 2/158 (1%)
Query: 41 INHSWYKSSSRIALYMSTENE-IDTAPLIKHIQARGAAAFVPQYAGGRMRMLHLET-GDE 98
+ H Y+ S RI++Y++ + E +DT +++ + ++ +VPQY G +M M+ + + D
Sbjct: 1 MEHPAYQKSQRISVYLAMKKEEVDTDGILRKMFSQNKLCYVPQYIGPKMNMMKMSSMEDY 60
Query: 99 QTMPKTKHGISQHGKDQARDDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLR 158
+ +P+TK I Q D R+DAL+TGGLDLII PG+ FS+ G RLG G GYYD +
Sbjct: 61 EALPETKWKIKQPADDDVREDALKTGGLDLIIIPGLGFSKEGHRLGRGKGYYDIYQNRCV 120
Query: 159 LNPETAPKIVAVAFNCQVVDEVPTNEQDQKVDEVIFAE 196
P +A+AF Q+ + +P E D +D V++ +
Sbjct: 121 EETGVKPVTIALAFKEQICESIPITENDVTIDYVLYGD 158
>UniRef50_Q4AQ84 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Chlorobium phaeobacteroides BS1|Rep:
5-formyltetrahydrofolate cyclo-ligase - Chlorobium
phaeobacteroides BS1
Length = 194
Score = 100 bits (239), Expect = 3e-20
Identities = 65/188 (34%), Positives = 100/188 (53%), Gaps = 10/188 (5%)
Query: 9 AKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTEN--EIDTAP 66
+K +R E + A++ +EE + S ++ E V ++ + + +Y+S E+DTAP
Sbjct: 6 SKERIRRECRERRASMDSEEWRSASSLIAENVAGIQEFREARTVMMYLSMNERREVDTAP 65
Query: 67 LIKHIQARG-AAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGG 125
LI + G ++ +VP G + M+ GDE T + G + D D L
Sbjct: 66 LISLCASFGNSSLYVPVTRGETLCMVPFNEGDEVT--DGRFGQPEPVSDNGCADVLP--- 120
Query: 126 LDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQ 185
D++I P VA R G RLG+G GYYD+FI LRL T P +AVAF+ Q+V VP +
Sbjct: 121 -DVVILPVVAVDREGRRLGYGKGYYDRFIAGLRLQGAT-PFTLAVAFSFQLVSHVPEDPW 178
Query: 186 DQKVDEVI 193
D+K+D V+
Sbjct: 179 DEKIDCVV 186
>UniRef50_Q18VM6 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=2; Desulfitobacterium hafniense|Rep:
5-formyltetrahydrofolate cyclo-ligase -
Desulfitobacterium hafniense (strain DCB-2)
Length = 194
Score = 98.7 bits (235), Expect = 8e-20
Identities = 63/185 (34%), Positives = 98/185 (52%), Gaps = 8/185 (4%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 69
K LLR + + +ALT EE+ +SQ + V ++ + I L+M+ +E++T L +
Sbjct: 5 KRLLREHVLSLRSALTPEERASKSQRIRAIVTQTREFQEAGTIMLFMNFRDEVETTELAQ 64
Query: 70 HIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARD-DALETGGLDL 128
+ G +P+ A + + L + + GI + K + + D LE G
Sbjct: 65 KVLDLGKRLVLPRCAPKGVLIPALIGDLAKDIESGMWGIREPKKQELTEVDPLEIDG--- 121
Query: 129 IIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQK 188
I PG AF G+RLG+GGGYYD+F +R E PKI A+AF+CQ+VD +P D+K
Sbjct: 122 IFVPGAAFDGQGNRLGYGGGYYDRFFERVR---EGTPKI-ALAFHCQIVDRIPVEVYDKK 177
Query: 189 VDEVI 193
VD +I
Sbjct: 178 VDMLI 182
>UniRef50_A6LQ49 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Clostridium beijerinckii NCIMB 8052|Rep:
5-formyltetrahydrofolate cyclo-ligase - Clostridium
beijerinckii NCIMB 8052
Length = 196
Score = 98.7 bits (235), Expect = 8e-20
Identities = 58/186 (31%), Positives = 99/186 (53%), Gaps = 7/186 (3%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 69
K +LR EI K + EK++ + + E V + +YK + I +Y+S + EI+T IK
Sbjct: 7 KKILRKEILDKRKKIDVTEKEKMDERILETVYSSEYYKLAKNIFVYISFDTEINTRDFIK 66
Query: 70 HIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLI 129
+VP+ M +E + ++ +GI + D ++ LDLI
Sbjct: 67 ESLNNNKRIYVPRTEIKTRLMDAVEIKSLDNLSESSYGIPE---PSINDPYIDPNELDLI 123
Query: 130 IAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKI--VAVAFNCQVVDEVPTNEQDQ 187
I PGVAF + G R+G+G G+YD++ ++N + +I +A+A++ QV+D+VPT+ D
Sbjct: 124 IVPGVAFDKRGGRVGYGAGFYDRYFK--KVNKDNIKRITKLALAYDFQVLDKVPTSYHDV 181
Query: 188 KVDEVI 193
VD +I
Sbjct: 182 PVDYII 187
>UniRef50_Q97K31 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Clostridium acetobutylicum|Rep:
5-formyltetrahydrofolate cyclo-ligase - Clostridium
acetobutylicum
Length = 182
Score = 97.9 bits (233), Expect = 1e-19
Identities = 58/185 (31%), Positives = 103/185 (55%), Gaps = 8/185 (4%)
Query: 9 AKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLI 68
+K LR + K +L + K + ++Y KVIN YKS++ I +++S ++E+DT +I
Sbjct: 4 SKKELRKNMVLKRDSLEPDLKSIKDNMIYNKVINSIQYKSANNIFVFVSYKSEVDTHNII 63
Query: 69 KHIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDL 128
+ A G FVP+ M E + K+ +GI + + +E ++L
Sbjct: 64 RTAIADGKKVFVPKVISKEKGMEAAEIRGFFDLEKSAYGI----LEPKSSNYIEPESIEL 119
Query: 129 IIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQK 188
++ PG+AF SG R+G+GGG+YD++++ L ++A K V + ++ QV+D+V N D
Sbjct: 120 LLVPGLAFDESGGRIGYGGGFYDRYMS---LLDKSAVK-VGICYDFQVIDKVIMNINDVP 175
Query: 189 VDEVI 193
VD++I
Sbjct: 176 VDKII 180
>UniRef50_A3LUI4 Cluster: 5,10-methenyltetrahydrofolate synthetase;
n=3; Saccharomycetales|Rep:
5,10-methenyltetrahydrofolate synthetase - Pichia
stipitis (Yeast)
Length = 207
Score = 97.5 bits (232), Expect = 2e-19
Identities = 60/205 (29%), Positives = 106/205 (51%), Gaps = 14/205 (6%)
Query: 1 MSPIKPNPAKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMST-E 59
MS +K AK LR +I + A++ E + QS +++K++ H ++ +++IALYM+ +
Sbjct: 1 MSSLKQ--AKTQLRRQIKESLRAISQESLQTQSNDIHKKLLGHPVFQKATKIALYMNMPD 58
Query: 60 NEIDTAPLIKHIQARGAAAFVP----QYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQ 115
+E+ T +I G ++P + GR + HL + K + GK Q
Sbjct: 59 SEVKTDAIIHSCYQMGKQVYLPRCKTEVVEGR-KNCHLVMLRVPSYEDVK-ALKPQGKYQ 116
Query: 116 ARD-----DALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAV 170
+ DA++ G LD++I PGV FS + R+GHG G+YD+FI P ++ +
Sbjct: 117 LLEPIEGVDAMDEGDLDVVIVPGVVFSTTKQRMGHGAGFYDEFIKFYNSKHNRRPYLIGL 176
Query: 171 AFNCQVVDEVPTNEQDQKVDEVIFA 195
+ Q V+ +PT E D +D ++ +
Sbjct: 177 GLHQQFVNSLPTEEHDWDLDSLVIS 201
>UniRef50_A5Z6A8 Cluster: Putative uncharacterized protein; n=1;
Eubacterium ventriosum ATCC 27560|Rep: Putative
uncharacterized protein - Eubacterium ventriosum ATCC
27560
Length = 175
Score = 97.1 bits (231), Expect = 2e-19
Identities = 59/184 (32%), Positives = 98/184 (53%), Gaps = 14/184 (7%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 69
K LR E+ AK +T+EE ++S + +++N+S Y S I Y S E+D P IK
Sbjct: 4 KKQLRKELIAKRKKMTDEEFSKKSLRICNRLLNNSQYLKSKVIYCYYSVNKEVDLLPFIK 63
Query: 70 HIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLI 129
G P+ G M +++ +E + G + A + DLI
Sbjct: 64 QALEDGKIIAFPKVKGQNMDFFEVKSLEE-----LEPGYFNIPEPPETTPAPKG---DLI 115
Query: 130 IAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQKV 189
I PGVAFS+ G+RLG+GGG+YD+F+ + ++ + VA++ Q+++ +PT E D+K+
Sbjct: 116 IVPGVAFSKKGERLGYGGGFYDRFLEHHKV------YTIGVAYDFQIMNSLPTEEHDRKL 169
Query: 190 DEVI 193
+E+I
Sbjct: 170 NEII 173
>UniRef50_Q3AE50 Cluster: 5-formyltetrahydrofolate cyclo-ligase
family protein; n=1; Carboxydothermus hydrogenoformans
Z-2901|Rep: 5-formyltetrahydrofolate cyclo-ligase family
protein - Carboxydothermus hydrogenoformans (strain
Z-2901 / DSM 6008)
Length = 192
Score = 96.3 bits (229), Expect = 4e-19
Identities = 60/187 (32%), Positives = 99/187 (52%), Gaps = 6/187 (3%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 69
K +LR EI K AA T E +S + + + Y+ + + +Y+ E+ T +I+
Sbjct: 4 KKVLRKEILNKRAAQTPAEIAAKSSRILTLLKAFAPYQQARTVMVYLDFRGEVKTREIIR 63
Query: 70 HIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLI 129
+ A G +P ++L + D + + +GI + K++AR A E +DL+
Sbjct: 64 DLWAYGKKVVIPVTVLSEKKLLPVYLRDFGDLVEGTYGILEP-KEEARTIA-EPEVIDLV 121
Query: 130 IAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQKV 189
+ PGVAF G+RLG+G G+YD+F+ NL + A K VA+AF Q+V ++PT D +
Sbjct: 122 LVPGVAFDLKGNRLGYGAGFYDRFLPNL----QPAVKKVALAFELQIVPKIPTGPHDIPM 177
Query: 190 DEVIFAE 196
D +I E
Sbjct: 178 DYIITEE 184
>UniRef50_A5DWB9 Cluster: Putative uncharacterized protein; n=1;
Lodderomyces elongisporus NRRL YB-4239|Rep: Putative
uncharacterized protein - Lodderomyces elongisporus
(Yeast) (Saccharomyces elongisporus)
Length = 216
Score = 96.3 bits (229), Expect = 4e-19
Identities = 59/198 (29%), Positives = 112/198 (56%), Gaps = 16/198 (8%)
Query: 9 AKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTEN-EIDTAPL 67
AK LLR +I K+A ++ E +QSQ + ++++ +K++ ++AL+M+ + E+ T P+
Sbjct: 10 AKKLLRVKIKHKLATISQESLSQQSQEILDRLVQSPIFKNAQKVALFMNMPDLEVKTLPI 69
Query: 68 IKHIQARGAAAFVPQY----AGGRMR----MLHLETGDE--QTMPKTKHGISQHGKDQAR 117
I+ + ++P+ R R ML++ T + + P+ K+ + + + +
Sbjct: 70 IQECYNQKKEVYLPRCNTISVPNRKRNYLSMLNVPTFQDILELRPQGKYQLLEPIEGK-- 127
Query: 118 DDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVV 177
DAL++G LDLI+ PGVAF++ +RLGHG G+YD+++ + E P +V +A Q+
Sbjct: 128 -DALDSGDLDLILMPGVAFNQQRERLGHGAGFYDEYLYTYKTKWEHLPLLVGLALEEQIT 186
Query: 178 DE--VPTNEQDQKVDEVI 193
+P D K+D++I
Sbjct: 187 TNGLIPVELHDFKLDQII 204
>UniRef50_A5DQN3 Cluster: Putative uncharacterized protein; n=1;
Pichia guilliermondii|Rep: Putative uncharacterized
protein - Pichia guilliermondii (Yeast) (Candida
guilliermondii)
Length = 214
Score = 95.9 bits (228), Expect = 6e-19
Identities = 61/200 (30%), Positives = 108/200 (54%), Gaps = 15/200 (7%)
Query: 9 AKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTEN-EIDTAPL 67
AK LR+ + ++ +T+ QS +V ++ ++S+ + +YM+ E+ T +
Sbjct: 5 AKRDLRSRVRKVLSGVTSGSLHGQSTVVCRTLLESEQFRSAKSVGVYMNMPTMEVQTESI 64
Query: 68 IKHIQARGAAAFVPQYAG-----GR----MRMLHLET-GDEQTM-PKTKHGISQHGKDQA 116
IK + A F+P+ + GR M M+H+ + GD + P+ K+ + + +
Sbjct: 65 IKACFDQQKAVFLPKCSSNARCEGRKKNYMSMIHVPSLGDVHNLEPQGKYRLLEPTEGT- 123
Query: 117 RDDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQV 176
+ T GLDL+I PG+AF++SG RLGHG G+YD+F+T + + P +V +A Q+
Sbjct: 124 --EVFNTAGLDLLILPGMAFTKSGRRLGHGAGFYDEFLTVYQSHFARVPYLVGLALLEQI 181
Query: 177 VDEVPTNEQDQKVDEVIFAE 196
VD++P E D +D +I E
Sbjct: 182 VDDIPHEEHDWDLDCIISQE 201
>UniRef50_Q9KD02 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Bacillus halodurans|Rep: 5-formyltetrahydrofolate
cyclo-ligase - Bacillus halodurans
Length = 186
Score = 93.5 bits (222), Expect = 3e-18
Identities = 53/184 (28%), Positives = 97/184 (52%), Gaps = 8/184 (4%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 69
K LRN I + + +++K SQ V + + + + + I + +S +E+ T +I
Sbjct: 4 KKALRNRIKKLLRSQPEQQRKEGSQRVADILFSLPEWNEAHAIGITISLPHEVQTELIIS 63
Query: 70 HIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLI 129
G VP+ G +M E + T G+ + + R ++ LDL+
Sbjct: 64 RGWEEGKQIAVPRVKKGTTQMTFYEIHSFSVLEDTFFGLREPKPSECRQ--IDGQELDLL 121
Query: 130 IAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQKV 189
+ PGVAF + G+RLG+GGGYYD+F+ + + K +A+A++ Q+V+ VPT+E+D++V
Sbjct: 122 LVPGVAFDQKGNRLGYGGGYYDRFLHSYK------GKTIALAYSQQLVESVPTDERDERV 175
Query: 190 DEVI 193
++
Sbjct: 176 QMIV 179
>UniRef50_Q1AWE3 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Rubrobacter xylanophilus DSM 9941|Rep:
5-formyltetrahydrofolate cyclo-ligase - Rubrobacter
xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 196
Score = 93.5 bits (222), Expect = 3e-18
Identities = 56/186 (30%), Positives = 93/186 (50%), Gaps = 9/186 (4%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 69
KA +R E + AL ++R + V +V+ Y+++ + Y +E+DTA ++
Sbjct: 7 KAEIREEALRRREALGGVLRRRLGEEVLGRVLGLGEYRAAGVVLAYAGVGSELDTAGFMR 66
Query: 70 HIQARGAAAFVPQY--AGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLD 127
+ G +P+ R+ + +E + + +P GI + ++AR LE ++
Sbjct: 67 EVLGGGRRLVLPRVDREARRLELYEVEDPERELVPGV-WGIPEPNPERARRVGLEE--VE 123
Query: 128 LIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQ 187
++ PGVAF R G RLGHG GYYD+ + R P +VA AF Q+V+ VP D
Sbjct: 124 FVLVPGVAFDRRGGRLGHGAGYYDRLLGGAR----RLPPLVAAAFEAQIVERVPMEPHDV 179
Query: 188 KVDEVI 193
VD V+
Sbjct: 180 PVDLVV 185
>UniRef50_Q65HC6 Cluster: YqgN; n=1; Bacillus licheniformis ATCC
14580|Rep: YqgN - Bacillus licheniformis (strain DSM 13
/ ATCC 14580)
Length = 190
Score = 93.1 bits (221), Expect = 4e-18
Identities = 50/184 (27%), Positives = 93/184 (50%), Gaps = 8/184 (4%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 69
K LR+E+ ++A + +E +++ ++ K+ +K +S IAL +S E+ T P+I+
Sbjct: 2 KRSLRSEVRKRLANMPEQEFHLKAEAIHRKLFQSKQWKKASVIALTVSRNREVPTKPIIE 61
Query: 70 HIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLI 129
+ G +P+ +M DE + G+ + + + +E +D I
Sbjct: 62 QARLEGKTVCIPKCMPETKKMHFRSYQDESDLEVVYFGLQE--PIVHKTERMEPEDIDFI 119
Query: 130 IAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQKV 189
+ PG+ + R G R+G+GGGYYD+++ +TA ++AF CQV+ VP D V
Sbjct: 120 LVPGICYDRRGYRIGYGGGYYDRYLAG--FTKDTA----SLAFECQVIGHVPNEPHDIPV 173
Query: 190 DEVI 193
+V+
Sbjct: 174 KQVL 177
>UniRef50_Q83F82 Cluster: 5-formyltetrahydrofolate cyclo-ligase
family protein; n=3; Coxiella burnetii|Rep:
5-formyltetrahydrofolate cyclo-ligase family protein -
Coxiella burnetii
Length = 197
Score = 92.3 bits (219), Expect = 7e-18
Identities = 54/186 (29%), Positives = 97/186 (52%), Gaps = 3/186 (1%)
Query: 9 AKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLI 68
+K LR+++ + L+ +EK + S+I+ +K++ S +KSS R+A Y+S + E+D +
Sbjct: 6 SKKQLRDQLRQRRNELSFQEKNKASEIICKKIMGLSIFKSSERLAFYLSHDGEVDIRIAL 65
Query: 69 KHIQARGAAAFVPQYAGGRMRMLHLETGD-EQTMPKTKHGISQHGKDQARDDALETGGLD 127
A F+P L + + + K + GI + D R+ + T LD
Sbjct: 66 SKALEVKKACFLPLLHCTLDHHLDFYSYHLKSELIKNRFGIGE--PDPTRETPIATKELD 123
Query: 128 LIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQ 187
LI P VAF + G+RLG G GYYD+ + L+ + PK++ VA+ Q ++ + + D
Sbjct: 124 LIFLPLVAFDKDGNRLGRGAGYYDRALAFLKDSNAQKPKLIGVAYEFQKINSITAEKWDI 183
Query: 188 KVDEVI 193
++ V+
Sbjct: 184 PLNSVV 189
>UniRef50_A3IGL7 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Bacillus sp. B14905|Rep: 5-formyltetrahydrofolate
cyclo-ligase - Bacillus sp. B14905
Length = 197
Score = 92.3 bits (219), Expect = 7e-18
Identities = 52/184 (28%), Positives = 99/184 (53%), Gaps = 7/184 (3%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 69
K LRN++ +A + +E +RQS+ V ++V+ + ++ I + +S + E+DT LI+
Sbjct: 3 KTTLRNKVRETLAIMNDEVYRRQSKAVVKRVLQEPYIIEANTIGITISNQPEVDTILLIE 62
Query: 70 HIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLI 129
+ G VP+ + R + + +T + + R + ++ +D+I
Sbjct: 63 ELWQLGKKVAVPK-CHPKTREMTFYAIESFAQLETVY-MHLREPIPERCELVDANEMDII 120
Query: 130 IAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQKV 189
+ PGV F R G R+G+GGGYYD+++ N + K++++ F+ Q+V+ VPT E D V
Sbjct: 121 LVPGVVFDRLGYRIGYGGGYYDRYVLNYKKG-----KLMSLLFDEQIVNRVPTEEHDCPV 175
Query: 190 DEVI 193
D ++
Sbjct: 176 DIIV 179
>UniRef50_Q97NE8 Cluster: 5-formyltetrahydrofolate cyclo-ligase
family protein; n=29; Streptococcus|Rep:
5-formyltetrahydrofolate cyclo-ligase family protein -
Streptococcus pneumoniae
Length = 179
Score = 91.9 bits (218), Expect = 9e-18
Identities = 55/188 (29%), Positives = 100/188 (53%), Gaps = 14/188 (7%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 69
K+ LR ++ ++ A++ E+K+ Q + E+++ H +Y+ + IA Y+S +E T LI+
Sbjct: 2 KSELRKQVLHEMKAISQEQKQAIDQALTERLLQHPFYQEAKVIATYLSFSHEFQTQELIE 61
Query: 70 HIQARGAAAFVPQ-YAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDL 128
G +P+ Y GRM + D Q + KT + + D + ++ +DL
Sbjct: 62 QALKDGKKVLIPKTYPKGRMDFV---VYDPQQLVKTFFALLELQGDL---EVVDASQIDL 115
Query: 129 IIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQK 188
I PG+AF+ G R+G+GGGYYD+++ + + + ++ + CQ+ D +P N D
Sbjct: 116 IHVPGLAFTTKGYRIGYGGGYYDRYLEHF------SGRTLSTIYPCQIQDFIPEN-HDIP 168
Query: 189 VDEVIFAE 196
V EV+ E
Sbjct: 169 VQEVLIDE 176
>UniRef50_A5N8A1 Cluster: 5-formyltetrahydrofolate
cyclo-ligase-related protein; n=1; Clostridium kluyveri
DSM 555|Rep: 5-formyltetrahydrofolate
cyclo-ligase-related protein - Clostridium kluyveri DSM
555
Length = 181
Score = 91.5 bits (217), Expect = 1e-17
Identities = 57/186 (30%), Positives = 97/186 (52%), Gaps = 11/186 (5%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 69
K +R + K L N +K++ I++EKVI Y + + +++S ++E DT +IK
Sbjct: 3 KFYIRKIMKEKRDNLCNWQKEKLDSIIFEKVIKSEEYNKAKSVFIFVSYKSEADTHNIIK 62
Query: 70 HIQARGAAAFVPQ--YAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLD 127
G VP+ Y G M + + +E K G + + Q + +E +D
Sbjct: 63 AALKDGKLVCVPKVMYKSGYMEAVGIYDFNE-----LKEGAYKILEPQNTNLKVEETSID 117
Query: 128 LIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQ 187
+ PG+AF +SG R+G+GGGYYD+F+ LR K + +A++ Q++D+VP + D
Sbjct: 118 ICYVPGLAFDKSGGRVGYGGGYYDRFLKKLR----NDSKKIGLAYSFQILDKVPMGKYDV 173
Query: 188 KVDEVI 193
+D VI
Sbjct: 174 CMDGVI 179
>UniRef50_Q7MTT7 Cluster: 5-formyltetrahydrofolate cyclo-ligase
family protein; n=1; Porphyromonas gingivalis|Rep:
5-formyltetrahydrofolate cyclo-ligase family protein -
Porphyromonas gingivalis (Bacteroides gingivalis)
Length = 185
Score = 90.2 bits (214), Expect = 3e-17
Identities = 53/171 (30%), Positives = 94/171 (54%), Gaps = 12/171 (7%)
Query: 24 LTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK-HIQARGAAAFVPQ 82
L E ++R SQ + E++ + + RI LY + +E D L++ ++Q + F+P+
Sbjct: 18 LAAENRERWSQSIIERIRRLDIFADAKRIGLYHALPDEPDLTGLLREYVQTK--QLFIPR 75
Query: 83 YAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLIIAPGVAFSRSGDR 142
G + + TG+ + +GI++ D A A+ LDL++ PGVAF R G R
Sbjct: 76 VEGDDIAF-YAYTGEADLEAEGAYGIAEPTADAAT--AILPSSLDLLLVPGVAFDRKGSR 132
Query: 143 LGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQKVDEVI 193
+G G GYYD+F+ P T +++ V F+ ++++E+PT+ D+ +D VI
Sbjct: 133 MGRGKGYYDRFL------PATQVRLIGVTFSYRLLEELPTDPWDRPMDGVI 177
>UniRef50_A0L5J2 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Magnetococcus sp. MC-1|Rep:
5-formyltetrahydrofolate cyclo-ligase - Magnetococcus
sp. (strain MC-1)
Length = 196
Score = 89.8 bits (213), Expect = 4e-17
Identities = 53/185 (28%), Positives = 90/185 (48%), Gaps = 10/185 (5%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 69
K LR + A AL + + +++H+W + R+ALY + E+D APL+
Sbjct: 6 KEALRKTLLAWRGALDPAWRASANAAAVAHLLSHAWLGQAERVALYCAIRGELDPAPLLA 65
Query: 70 HIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLI 129
+ G ++P+ G ++ + + GI Q G D+A+ +E G +DL+
Sbjct: 66 PLWQMGKILYLPRLEAGASQIRFARHQQGEVWQRGPFGIPQPGPDRAQ---IEPGAVDLM 122
Query: 130 IAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPK-IVAVAFNCQVVDEVPTNEQDQK 188
+ P V F G RLG+GGG+YD+ + R PK +V + F Q V+ +P + D
Sbjct: 123 LVPLVGFDAQGGRLGYGGGFYDRTLAGQR------PKLLVGLGFAGQQVEHLPRADHDIP 176
Query: 189 VDEVI 193
+D V+
Sbjct: 177 LDAVV 181
>UniRef50_Q896J3 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=6; Clostridium|Rep: 5-formyltetrahydrofolate
cyclo-ligase - Clostridium tetani
Length = 183
Score = 89.0 bits (211), Expect = 6e-17
Identities = 54/187 (28%), Positives = 96/187 (51%), Gaps = 7/187 (3%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 69
K LR + K L+ ++ ++E+VI +YK ++ I +++S ++E+ T +IK
Sbjct: 4 KKELREKSMVKRDGLSKDKINEYDGNIFERVIESKYYKEANCIFIFVSYKSEVHTHEIIK 63
Query: 70 HIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLI 129
VP+ + M +E + + GI + + D +E +D++
Sbjct: 64 RALKDNKRVCVPKIISLKDGMEVIEIKSFSELKPGEKGILEPVDFSRKVDPME---IDIV 120
Query: 130 IAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQKV 189
PG+AF G RLG+GGG+YDKF L+ + PK V +A++ Q+VD VP E D ++
Sbjct: 121 FTPGLAFDNKGGRLGYGGGFYDKFFKRLK---KDTPK-VGLAYSFQIVDFVPMYEWDVRI 176
Query: 190 DEVIFAE 196
+++I E
Sbjct: 177 NDIIVNE 183
>UniRef50_A6TVJ5 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=2; Clostridiaceae|Rep: 5-formyltetrahydrofolate
cyclo-ligase - Alkaliphilus metalliredigens QYMF
Length = 192
Score = 88.6 bits (210), Expect = 9e-17
Identities = 57/185 (30%), Positives = 97/185 (52%), Gaps = 7/185 (3%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 69
K LR ++ A+ L++ + +SQ V + N S YK + + LY+S E+ T +I+
Sbjct: 2 KNTLRKQLLAQREILSSVHMETKSQQVRSSLFNFSPYKKAQHVMLYVSFGKEVITRGIIQ 61
Query: 70 HIQARGAAAFVPQYAGGRMRMLHLETGD-EQTMPKTKHGISQHGKDQARDDALETGGLDL 128
+ + F+P ++ E D ++ + G+ + K+ R ++ LD
Sbjct: 62 DLLDQNKRVFIPVCVPKTKELIISELLDFDEDLEIGHFGVLEPKKEALRP--VDPKILDF 119
Query: 129 IIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQK 188
II PG+AF G R+G+GGGYYD+F+ + + PK V++AF+ V+D VPT+ D
Sbjct: 120 IIVPGLAFDSQGYRIGYGGGYYDRFLPKI---SDKVPK-VSLAFDEFVIDSVPTDSFDIP 175
Query: 189 VDEVI 193
VD +I
Sbjct: 176 VDFII 180
>UniRef50_A1SSJ1 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=3; Gammaproteobacteria|Rep: 5-formyltetrahydrofolate
cyclo-ligase - Psychromonas ingrahamii (strain 37)
Length = 196
Score = 88.6 bits (210), Expect = 9e-17
Identities = 51/182 (28%), Positives = 95/182 (52%), Gaps = 4/182 (2%)
Query: 13 LRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQ 72
+R++I L+ ++K+ + ++ ++I HS + + +I++ ++ + EIDT ++
Sbjct: 10 IRHQIRTARRDLSGLQQKQDADSLFSRLIKHSRVQQAGKISVTLAYDGEIDTLRFVEWCW 69
Query: 73 ARGAAAFVPQ-YAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLIIA 131
+ ++P + + +L LE + M +HGI + +Q DA LDLI
Sbjct: 70 QKNKKIYLPVIHPFNKGHLLFLEYTTKTEMVLNQHGIFEPKLNQL--DACPMKELDLIFT 127
Query: 132 PGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQKVDE 191
P VAF G+R+G GGGYYD+ + +T P + +A +CQ V ++P E D + E
Sbjct: 128 PLVAFDTQGNRIGMGGGYYDRMLAPW-FKDKTGPYPIGLAHDCQQVQQLPVEEWDVPLPE 186
Query: 192 VI 193
+I
Sbjct: 187 II 188
>UniRef50_Q6CAN2 Cluster: Similar to sp|P40099 Saccharomyces
cerevisiae YER183c FAU1 similarity to human 5; n=1;
Yarrowia lipolytica|Rep: Similar to sp|P40099
Saccharomyces cerevisiae YER183c FAU1 similarity to
human 5 - Yarrowia lipolytica (Candida lipolytica)
Length = 212
Score = 88.2 bits (209), Expect = 1e-16
Identities = 64/202 (31%), Positives = 104/202 (51%), Gaps = 19/202 (9%)
Query: 8 PAKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTEN-EIDTAP 66
PAK LR IA ++A ++ + ++QS + + YKS+ IA YM+ ++ E++T
Sbjct: 4 PAKQQLRKLIAQRVADVSKDSIQKQSLATTAALRTLNEYKSAQNIAFYMNMDSGELETMD 63
Query: 67 LIKHIQARGAAAFVPQYAG-------------GRMRMLHL-ETGDEQTM-PKTKHGISQH 111
+I++ F+P+ +RML + + D Q + P+ + + +
Sbjct: 64 MIRNAFEDKKRVFLPRIEKLADTADKIHPCQKSELRMLEIVDFKDVQNLQPRGPYKLKEP 123
Query: 112 GKDQARDDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVA 171
KD D LE+GGL LI+ PGVA + RLGHG G+YD +I + PK+V V
Sbjct: 124 TKDAK--DVLESGGLGLIVLPGVAMTPQCARLGHGVGFYDAYI-HKHEKLLGVPKLVGVC 180
Query: 172 FNCQVVDEVPTNEQDQKVDEVI 193
Q+VDE+P E D+ +D V+
Sbjct: 181 LREQLVDELPLEEHDRLLDVVV 202
>UniRef50_Q2RGK7 Cluster: 5-formyltetrahydrofolate cyclo-ligase
precursor; n=1; Moorella thermoacetica ATCC 39073|Rep:
5-formyltetrahydrofolate cyclo-ligase precursor -
Moorella thermoacetica (strain ATCC 39073)
Length = 202
Score = 87.4 bits (207), Expect = 2e-16
Identities = 58/186 (31%), Positives = 98/186 (52%), Gaps = 9/186 (4%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 69
K LR +I + +L+ ++ +S ++ +V+ ++ + + Y+S +E+ T LI+
Sbjct: 2 KKQLRRQIITRRNSLSQAAREEKSAVITRRVLGLPAWEKARLVMCYVSFGSEVLTPSLIQ 61
Query: 70 HIQARGAAAFVPQYAGGRMRMLHLETGD--EQTMPKTKHGISQHGKDQARDDALETGGLD 127
++G VP R+L E D P T GI + + R ++ G +D
Sbjct: 62 AALSQGKRVTVPLCIPEGRRLLASEVLDFPGDLQPGT-WGILEPRPETLRP--VDPGDID 118
Query: 128 LIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQ 187
L++ PGVAF R+G+RLG+GGGYYD+F+ LR T +A+AF Q+V +V D+
Sbjct: 119 LVLVPGVAFDRAGNRLGYGGGYYDRFLATLRPGALT----IALAFAEQIVADVYPEVHDR 174
Query: 188 KVDEVI 193
VD V+
Sbjct: 175 PVDMVV 180
>UniRef50_Q7URX2 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Pirellula sp.|Rep: 5-formyltetrahydrofolate
cyclo-ligase - Rhodopirellula baltica
Length = 205
Score = 85.8 bits (203), Expect = 6e-16
Identities = 51/179 (28%), Positives = 91/179 (50%), Gaps = 10/179 (5%)
Query: 18 AAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQARGAA 77
AA+ A +K SQ++ + Y+ + + Y+ +E+ T + G
Sbjct: 21 AAQAARREQADKGGLSQLIVNAITQLPVYQEAECVMWYIDVRSEVRTRHALPLAIDSGKR 80
Query: 78 AFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARD---DALETGGLDLIIAPGV 134
VP G + + LE+ DE + + + I + +++ RD + + + LD+++ PGV
Sbjct: 81 IVVPFCLDGELELFRLESMDE--LAEGMYEILEP-REELRDLVPNRVRSSDLDVVLVPGV 137
Query: 135 AFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQKVDEVI 193
AF R G R+GHG GYYDK + N+R + +++ +AF CQ+V VP D ++D V+
Sbjct: 138 AFDRHGGRVGHGKGYYDKLLGNVR----SDTRLIGLAFECQMVGAVPVQAHDIRMDMVV 192
>UniRef50_Q03Y24 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Leuconostoc mesenteroides subsp. mesenteroides ATCC
8293|Rep: 5-formyltetrahydrofolate cyclo-ligase -
Leuconostoc mesenteroides subsp. mesenteroides (strain
ATCC 8293 /NCDO 523)
Length = 178
Score = 85.4 bits (202), Expect = 8e-16
Identities = 55/187 (29%), Positives = 100/187 (53%), Gaps = 12/187 (6%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 69
K+ LR + A +A ++KR+ + +Y + ++S+ IA+ +S E E++T+P+I
Sbjct: 4 KSELRIQQKAALARENLMKRKREEEQLYALLFQTPEWQSADSIAVTLSMEFELNTSPIII 63
Query: 70 HIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLI 129
+ VP+ +M + + D T +T G+ ++ D+ LDL+
Sbjct: 64 KAWEKSKRVLVPKIINHKMIFVEI---DSNTRYQT--GMLNI-REPLIDNYQAVEQLDLV 117
Query: 130 IAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQKV 189
I PG+AF+ SG RLG G GYYD+F+ + A ++VA + Q++D++PT DQ V
Sbjct: 118 IVPGLAFTVSGKRLGFGAGYYDRFLEHY------AGHTISVALSTQLLDDLPTENHDQTV 171
Query: 190 DEVIFAE 196
+++A+
Sbjct: 172 QRILYAK 178
>UniRef50_Q5WH98 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Bacillus clausii KSM-K16|Rep:
5-formyltetrahydrofolate cyclo-ligase - Bacillus clausii
(strain KSM-K16)
Length = 187
Score = 85.0 bits (201), Expect = 1e-15
Identities = 51/185 (27%), Positives = 97/185 (52%), Gaps = 8/185 (4%)
Query: 9 AKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLI 68
+K +RN+++ ++ L K++S + + ++ + ++ IAL +S E++TAPLI
Sbjct: 3 SKQNIRNDVSKQLNMLPAHVYKQRSTRLADLLMQQDVWNQATTIALTVSRFPEVETAPLI 62
Query: 69 KHIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDL 128
A +P+ M + + + K+G+ + +++A + L+L
Sbjct: 63 AGALAENKKVVLPRINMKERTMAFFYITSTEELVENKYGLFEPKQEEAC--LVRPDELEL 120
Query: 129 IIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQK 188
I+ PGVAF+++G RLG GGG+YD+F+ P + VA+ F Q+ ++PT D
Sbjct: 121 IVVPGVAFTKAGKRLGLGGGFYDRFL------PSCSGLTVALCFREQLFSDLPTEPHDVL 174
Query: 189 VDEVI 193
+D+VI
Sbjct: 175 IDKVI 179
>UniRef50_Q41FV0 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Exiguobacterium sibiricum 255-15|Rep:
5-formyltetrahydrofolate cyclo-ligase - Exiguobacterium
sibiricum 255-15
Length = 182
Score = 84.2 bits (199), Expect = 2e-15
Identities = 56/184 (30%), Positives = 95/184 (51%), Gaps = 13/184 (7%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 69
K +R I ++ L N E+K+Q +Y+++ +K++ IA+ +S NE T P+I
Sbjct: 3 KQEIRRWITDQLNRLENREQKQQQ--IYDQLFELPEWKNAQSIAVTLSFRNECATDPIIL 60
Query: 70 HIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLI 129
G +P+ M+ E + +TK GI + DQA + +L + +DL
Sbjct: 61 KAWQLGKQVVIPKVIQQEMKFF--EYVPNSPLIETKMGIREPD-DQANEQSLRS--VDLC 115
Query: 130 IAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQKV 189
+ PG AF+R+G R+G GGG+YD+ +T + VAV F+CQ+V + DQ V
Sbjct: 116 LVPGRAFTRAGYRIGWGGGFYDRALT------DYPGHTVAVTFDCQLVSDFEVEPFDQPV 169
Query: 190 DEVI 193
+++
Sbjct: 170 QKIV 173
>UniRef50_A5VKU2 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=2; Lactobacillus reuteri|Rep: 5-formyltetrahydrofolate
cyclo-ligase - Lactobacillus reuteri F275
Length = 184
Score = 84.2 bits (199), Expect = 2e-15
Identities = 57/190 (30%), Positives = 101/190 (53%), Gaps = 17/190 (8%)
Query: 9 AKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLI 68
+K LR A++ L + + + + + + + + IA+ +S EIDTAP+I
Sbjct: 4 SKKELRQAYIARLQQLDLNTRLYEERKLASLLYDQPEWTGAKTIAVTLSQSFEIDTAPII 63
Query: 69 KHIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQ--HGKDQARDDALETGGL 126
H + +G +P+ R +M +E ++ +T GI + GK + D+ +
Sbjct: 64 LHARHKGQQIVIPRTLPHR-QMEFVELNEDTDFDETSFGILEPHDGKVYSPDE------I 116
Query: 127 DLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVD--EVPTNE 184
DL++ PGVAF+ SG+RLG GGGYYD+++ N + PK V++A Q+ + E E
Sbjct: 117 DLMVVPGVAFTASGNRLGFGGGYYDRYLKNYK-----GPK-VSMALTTQLAEENEWEPEE 170
Query: 185 QDQKVDEVIF 194
DQ++D+V++
Sbjct: 171 FDQRIDKVLY 180
>UniRef50_A3DEZ8 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Clostridium thermocellum ATCC 27405|Rep:
5-formyltetrahydrofolate cyclo-ligase - Clostridium
thermocellum (strain ATCC 27405 / DSM 1237)
Length = 191
Score = 83.8 bits (198), Expect = 2e-15
Identities = 58/187 (31%), Positives = 94/187 (50%), Gaps = 9/187 (4%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 69
K LR E L+ EE +S+++ EK+I+ + +S + YM +NE+ T LI+
Sbjct: 4 KRELRKEALNIRKGLSEEEIIEKSKLITEKLISLDGFYNSKCVMAYMDFKNEVMTRFLIE 63
Query: 70 HIQARGAAAFVP--QYAGGRMRMLHLE-TGDEQTMPKTKHGISQHGKDQARDDALETGGL 126
H G +P G ++ E T E + +GI + K+ +R ++ +
Sbjct: 64 HCLNLGKIVALPLIDCVDGVKKIFPYELTNQEGCLKPGTYGILEPVKEFSRK--IDPKDI 121
Query: 127 DLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQD 186
DL++ PGVAF G R+G+G GYYD F+ +R + KI +AF+ QV +P E D
Sbjct: 122 DLVVVPGVAFDVKGGRIGYGAGYYDIFLREVR---KDCLKI-GIAFDIQVFPSIPKEEHD 177
Query: 187 QKVDEVI 193
+D V+
Sbjct: 178 ILMDAVV 184
>UniRef50_A4SLF4 Cluster: 5-formyltetrahydrofolate cyclo-ligase
family protein; n=10; Gammaproteobacteria|Rep:
5-formyltetrahydrofolate cyclo-ligase family protein -
Aeromonas salmonicida (strain A449)
Length = 202
Score = 83.4 bits (197), Expect = 3e-15
Identities = 53/182 (29%), Positives = 93/182 (51%), Gaps = 4/182 (2%)
Query: 13 LRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQ 72
LR I + +L+ E++ +Q + + HS ++ RIALY++ + E++ P I +
Sbjct: 15 LRQLIRLRRKSLSQAEQQEAAQQLVAQFKQHSEILAARRIALYLANDGELNPLPAIHWLW 74
Query: 73 ARGAAAFVPQ-YAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLIIA 131
A+ ++P + +L L M + ++GI++ D ++ + LDLI
Sbjct: 75 AQQKEVYLPVLHPFTPGHLLFLRYTATSPMTRNRYGIAEPELDMSQ--VVPHSTLDLICT 132
Query: 132 PGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQKVDE 191
P VAF G+RLG GGGYYD+ + + PK + +A +CQ VD VP + D + +
Sbjct: 133 PLVAFDAEGNRLGMGGGYYDRTLACWH-EHKLGPKPLGLAHDCQQVDAVPQEQWDVPLPQ 191
Query: 192 VI 193
+I
Sbjct: 192 II 193
>UniRef50_A6VM34 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=3; Pasteurellaceae|Rep: 5-formyltetrahydrofolate
cyclo-ligase - Actinobacillus succinogenes 130Z
Length = 189
Score = 82.6 bits (195), Expect = 6e-15
Identities = 59/187 (31%), Positives = 92/187 (49%), Gaps = 10/187 (5%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 69
+A LR +I LT E+ R +Q V +K +N + + I LY+S + EI T PLI
Sbjct: 8 RAQLRRQIRKTRQNLTALEQIRAAQTVTQKALNLIAQRHAEHIGLYLSFDGEISTRPLID 67
Query: 70 HIQARGAAAFVP---QYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGL 126
+ A+ ++P + G M LH T + + MP +G+ + L L
Sbjct: 68 ALWAQRKNVYLPVLHPFCKGYMLFLHY-TPETELMP---NGLGIPEPRLNVKNILPINRL 123
Query: 127 DLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQD 186
D+I P VAF + G+RLG GGG+YD+ + + A V +A CQ VDE+P D
Sbjct: 124 DIIFTPLVAFDKQGNRLGMGGGFYDRTLQDWHEKNFIA---VGLAHQCQQVDELPVENWD 180
Query: 187 QKVDEVI 193
+ +++
Sbjct: 181 IPLFDIL 187
>UniRef50_Q72F49 Cluster: 5-formyltetrahydrofolate cyclo-ligase
family protein; n=2; Desulfovibrio vulgaris subsp.
vulgaris|Rep: 5-formyltetrahydrofolate cyclo-ligase
family protein - Desulfovibrio vulgaris (strain
Hildenborough / ATCC 29579 / NCIMB8303)
Length = 283
Score = 82.2 bits (194), Expect = 7e-15
Identities = 55/191 (28%), Positives = 91/191 (47%), Gaps = 6/191 (3%)
Query: 9 AKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLI 68
AK LR E+ + L EE +R + ++ H + ++ ++ LY++ NE+DT L+
Sbjct: 91 AKTALRREMLQRRRDLDREEAQRHGALAQAALLAHPAWVTARQVVLYVAVRNELDTDLLL 150
Query: 69 KHIQARGAAAFVPQYAGGRMRMLHLETG-DEQTMPKTKHGISQHGKDQAR--DDALETGG 125
+ G +P+ ++ L + HGI + + D T
Sbjct: 151 RTAWEAGKEVLLPRCDPACSGVMCLAPCLCAADLGPGSHGIPEPSPLRCPPVDPQSPTFA 210
Query: 126 LDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQ 185
DL I PGVAF R G+RLG+GGGYYD+F++ + +A +V A Q+VD +P
Sbjct: 211 PDLAIIPGVAFDRQGNRLGYGGGYYDRFLSTPGM---SATPLVGFAHAFQIVDALPAEAW 267
Query: 186 DQKVDEVIFAE 196
D+ V+ + E
Sbjct: 268 DRPVNALCTEE 278
>UniRef50_Q2ADA7 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Halothermothrix orenii H 168|Rep:
5-formyltetrahydrofolate cyclo-ligase - Halothermothrix
orenii H 168
Length = 193
Score = 81.4 bits (192), Expect = 1e-14
Identities = 57/185 (30%), Positives = 88/185 (47%), Gaps = 9/185 (4%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 69
KA LR +++ E + S + K +N + I Y+ST +E++T LI
Sbjct: 4 KAELRKLFMGFRSSINPERRHELSISINNKFLNLREVSVAQEIMCYVSTGSEVETRDLIT 63
Query: 70 HIQARGAAAFVPQYAGGRMRMLHLETGD-EQTMPKTKHGISQHGKDQARDDALETGGLDL 128
+ G VP + + D E + + +GI + Q R D GLD+
Sbjct: 64 KLIGYGKQVLVPYCITDKKEIKISPIKDLENDLVEGAYGIPE---PQNRVDT-PLKGLDI 119
Query: 129 IIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQK 188
+I PG+ FSR G R+G+GGGYYD+F+ L N T V ++ ++D +P + DQ
Sbjct: 120 VIVPGIVFSRDGYRIGYGGGYYDRFLVKLPDNVLT----VGFTYHALLLDNLPIDRYDQP 175
Query: 189 VDEVI 193
VD VI
Sbjct: 176 VDMVI 180
>UniRef50_P0AC29 Cluster: Uncharacterized protein ygfA; n=23;
Enterobacteriaceae|Rep: Uncharacterized protein ygfA -
Escherichia coli O157:H7
Length = 182
Score = 81.4 bits (192), Expect = 1e-14
Identities = 52/174 (29%), Positives = 90/174 (51%), Gaps = 10/174 (5%)
Query: 23 ALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQARGAAAFVP- 81
ALT E+++ Q +++ + + +A+++S + E+DT PLI+ + G ++P
Sbjct: 8 ALTPEQQQEMGQQAATRMMTYPPVVMAHTVAVFLSFDGELDTQPLIEQLWRAGKRVYLPV 67
Query: 82 --QYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLIIAPGVAFSRS 139
++ G + L+ E M + K K RD L LD++I P VAF
Sbjct: 68 LHPFSAGNLLFLNYHPQSELVMNRLK---IHEPKLDVRD-VLPLSRLDVLITPLVAFDEY 123
Query: 140 GDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQKVDEVI 193
G RLG GGG+YD+ + N + + +T P V A +CQ+V+++P E D + V+
Sbjct: 124 GQRLGMGGGFYDRTLQNWQ-HYKTQP--VGYAHDCQLVEKLPVEEWDIPLPAVV 174
>UniRef50_Q0SQM2 Cluster: 5-formyltetrahydrofolate cyclo-ligase
family protein; n=3; Clostridium perfringens|Rep:
5-formyltetrahydrofolate cyclo-ligase family protein -
Clostridium perfringens (strain SM101 / Type A)
Length = 192
Score = 81.0 bits (191), Expect = 2e-14
Identities = 53/191 (27%), Positives = 99/191 (51%), Gaps = 13/191 (6%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 69
K LR EI K + K + + + ++ YK+S + +Y++ ++E++T +IK
Sbjct: 3 KGELRKEIKLKRENIDRNTKLMADEKIRKTLLESEIYKNSKVVFIYVNMDSEVNTVEIIK 62
Query: 70 HIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGL--- 126
+ A VP+ ++ ++ ++ + +++ G + ++E +
Sbjct: 63 ELLASDKKVAVPKVIPVSLKERQMKALKIDSLLQ----LNESGAFGILEPSIECKDISEE 118
Query: 127 -DLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQ 185
DLII PG+AF G+RLG+GGG+YD+F++ P + K VA+ ++ QV DE+P
Sbjct: 119 VDLIIIPGLAFDLKGNRLGYGGGFYDRFLSKY---PNS--KRVALCYDFQVFDEIPHEFF 173
Query: 186 DQKVDEVIFAE 196
D+KVD +I E
Sbjct: 174 DEKVDLIISEE 184
>UniRef50_A6CNU5 Cluster: Possible 5-formyltetrahydrofolate
cyclo-ligase; n=1; Bacillus sp. SG-1|Rep: Possible
5-formyltetrahydrofolate cyclo-ligase - Bacillus sp.
SG-1
Length = 187
Score = 81.0 bits (191), Expect = 2e-14
Identities = 52/184 (28%), Positives = 91/184 (49%), Gaps = 8/184 (4%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 69
K LR + A ++AL + +S ++ ++ +K S IA+ +S E+DT +I+
Sbjct: 3 KKELRKKQKALLSALERHVYEHKSYLIASRLYETEEWKRSETIAVTVSNFPEVDTWQIIR 62
Query: 70 HIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLI 129
G VP+ + + K +G+ + + ++ + +DL+
Sbjct: 63 KGWEEGKRMLVPKCVPMDKELNFYYLDSFAGLEKVFYGLFEPAPE--KNILADPADIDLV 120
Query: 130 IAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQKV 189
I PG+AF SG RLG GGGYYD+F+ N + +++AF Q+V+EVP E D V
Sbjct: 121 IVPGLAFMNSGYRLGFGGGYYDRFLVNYQ------GSTLSLAFQEQLVEEVPVQEFDIPV 174
Query: 190 DEVI 193
D+++
Sbjct: 175 DKIV 178
>UniRef50_A4J8I3 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Desulfotomaculum reducens MI-1|Rep:
5-formyltetrahydrofolate cyclo-ligase - Desulfotomaculum
reducens MI-1
Length = 191
Score = 81.0 bits (191), Expect = 2e-14
Identities = 55/184 (29%), Positives = 87/184 (47%), Gaps = 9/184 (4%)
Query: 13 LRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQ 72
+R ++ +AL E +S ++ E++++ Y+ + I +Y+ E+ T LI H
Sbjct: 6 IRKKVLEVRSALKKSEVADKSSVIVERLVSFEPYRRAKTIMVYLDFRKEVKTESLINHAL 65
Query: 73 ARGAAAFVPQY-AGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLIIA 131
G VP A R L + +GI + + R +E LDLI+
Sbjct: 66 RSGKRVTVPVVNAVDRSMTPSLLVDFPGDLSIGSYGILEPAPENLRP--VEVQELDLIVV 123
Query: 132 PGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVD--EVPTNEQDQKV 189
PG F G+R+G+GGGYYD+FI LR + T VA+AF QV + V + DQ V
Sbjct: 124 PGTVFDHQGNRMGYGGGYYDRFIPRLRKDAVT----VALAFEFQVRENFSVLMGKYDQPV 179
Query: 190 DEVI 193
++
Sbjct: 180 QFIV 183
>UniRef50_A1WW94 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Halorhodospira halophila SL1|Rep:
5-formyltetrahydrofolate cyclo-ligase - Halorhodospira
halophila (strain DSM 244 / SL1)
(Ectothiorhodospirahalophila (strain DSM 244 / SL1))
Length = 203
Score = 81.0 bits (191), Expect = 2e-14
Identities = 51/185 (27%), Positives = 88/185 (47%), Gaps = 2/185 (1%)
Query: 9 AKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLI 68
AK +R + + + E++R + ++ + + R+A Y+ + E T ++
Sbjct: 3 AKRDIRRRLRNRRRRIPAGERRRAELRLRDETLRLVETQGVQRVAGYLDADGEAPTGAIL 62
Query: 69 KHIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDL 128
+ RG A ++P RM E + ++G+ + A + L LDL
Sbjct: 63 NALHQRGQAIYLPALRRQCRRMGFRRWAPEAPLRPNRYGVPEPPPGLAAE--LPVRDLDL 120
Query: 129 IIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQK 188
++AP VAF +G RLG GGG+YD LR P P+IV +AF+ Q V ++P + D
Sbjct: 121 VLAPLVAFDPAGRRLGMGGGFYDATFARLRRYPWHPPRIVGLAFSSQEVAQLPGDAWDLP 180
Query: 189 VDEVI 193
++ VI
Sbjct: 181 LEGVI 185
>UniRef50_A7I701 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Candidatus Methanoregula boonei 6A8|Rep:
5-formyltetrahydrofolate cyclo-ligase - Methanoregula
boonei (strain 6A8)
Length = 188
Score = 80.6 bits (190), Expect = 2e-14
Identities = 53/186 (28%), Positives = 100/186 (53%), Gaps = 14/186 (7%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 69
KA +R+ + A+ A+T +E+ +S++V ++ + + ++ S E E++T PLI+
Sbjct: 5 KARVRDILRARKEAMTQQERLEKSELVARHLM--LLIATGQTVMVFTSKEKEVNTQPLIE 62
Query: 70 HIQARGAAAFVP--QYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLD 127
+ A VP Q A +R+ +L T +P T G+ + + + + +D
Sbjct: 63 ALFAEKNPVVVPIIQKADVSLRLSYLRTM-AALVPST-FGVPEPIGSEIPANPKD---VD 117
Query: 128 LIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQ 187
+I+ P + F R+G R+G+G GYYD+F+ NP+ + VAF CQ ++ +P +E D
Sbjct: 118 VIVLPMLGFDRTGGRIGYGAGYYDRFLAQ---NPDLVK--IGVAFGCQEMEHLPVDENDI 172
Query: 188 KVDEVI 193
K+D ++
Sbjct: 173 KMDLIV 178
>UniRef50_Q6CX89 Cluster: Similarities with sp|P40099 Saccharomyces
cerevisiae YER183c FAU1 singleton; n=1; Kluyveromyces
lactis|Rep: Similarities with sp|P40099 Saccharomyces
cerevisiae YER183c FAU1 singleton - Kluyveromyces lactis
(Yeast) (Candida sphaerica)
Length = 291
Score = 80.2 bits (189), Expect = 3e-14
Identities = 56/201 (27%), Positives = 102/201 (50%), Gaps = 21/201 (10%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTEN-EIDTAPLI 68
K +LR ++ A + L+ E RQS+IV ++ K + IA +++ ++ E+ T PL+
Sbjct: 79 KQVLRTQVKAMLRGLSQAELARQSEIVSRHALSLVNAKGFTHIACFLNMDHSEMKTEPLV 138
Query: 69 KHIQARGAAAFVPQYAG------------GRMRMLHLETGDEQTMPKTKHGISQHGKDQA 116
+ + +G ++P+ + G ++ HL ++ + + + GK +
Sbjct: 139 ESLFKQGKTVYLPRCSSTSVSKQVDLRQDGALKRPHLVFYRFDSLAQVQ-ALQPQGKYKL 197
Query: 117 RD------DALETGGLDLIIAPGVAF-SRSGDRLGHGGGYYDKFITNLRLNPETAPKIVA 169
R+ + L T L++I+ PGVAF ++G R+GHG GYYD +I+ P +V
Sbjct: 198 REPVRTDPEPLPTPALEVILMPGVAFCKKNGARMGHGAGYYDDYISRHIHYTGKKPLLVG 257
Query: 170 VAFNCQVVDEVPTNEQDQKVD 190
+A Q+VD+VP + D VD
Sbjct: 258 LALEEQLVDDVPLEQHDYTVD 278
>UniRef50_Q603N0 Cluster: 5-formyltetrahydrofolate cyclo-ligase
family protein; n=1; Methylococcus capsulatus|Rep:
5-formyltetrahydrofolate cyclo-ligase family protein -
Methylococcus capsulatus
Length = 221
Score = 79.8 bits (188), Expect = 4e-14
Identities = 50/166 (30%), Positives = 82/166 (49%), Gaps = 7/166 (4%)
Query: 30 KRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQARGAAAFVPQYAGGRMR 89
+R S ++ + I+ W ++R+A Y+ + E+DT L ++++ RG AF+P +
Sbjct: 45 RRTSLLIAGRCIDAGWLDGAARMAAYLPNDGEVDTTVLFEYLRERGRTAFIPLLRKHTL- 103
Query: 90 MLHLETGDEQTMPKTKHGISQHGKD-QARDDALETGGLDLIIAPGVAFSRSGDRLGHGGG 148
G P ++GI + D + DA E LDL+ P VAF G RLG GGG
Sbjct: 104 WFGPYVGPAALRP-NRYGIPEPAIDGRMITDARE---LDLVFVPLVAFDPRGHRLGMGGG 159
Query: 149 YYDK-FITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQKVDEVI 193
YYD+ F L +P+++ +AF Q V+ + D +D +
Sbjct: 160 YYDRTFAFRLAEPARASPRLIGLAFEGQKVERLEARPWDVPLDTAV 205
>UniRef50_Q6AQJ8 Cluster: Probable 5-formyltetrahydrofolate
cyclo-ligase; n=1; Desulfotalea psychrophila|Rep:
Probable 5-formyltetrahydrofolate cyclo-ligase -
Desulfotalea psychrophila
Length = 191
Score = 79.0 bits (186), Expect = 7e-14
Identities = 46/185 (24%), Positives = 95/185 (51%), Gaps = 8/185 (4%)
Query: 12 LLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHI 71
LLR E+ K L++ E+ QS+ +K+ + + + + +Y+S E++T L+ +
Sbjct: 4 LLRREVLIKRKNLSDAERFEQSKRAVQKLSD--FLAEAQTVFVYLSYNGEVETFELVDKL 61
Query: 72 QARGAAAFVPQYAGGRMRMLHLETGDEQ---TMPKTKHGISQHGKDQARDDALETGGLDL 128
ARG +P + +++ +E + + + +GISQ +++L +D+
Sbjct: 62 LARGFRVTIPWTSLVDKKIIPVEIFENNFRMLLEEGPYGISQPSSTYMEENSLLAEEIDV 121
Query: 129 IIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQK 188
+I PG F R G R+G+GGG+YD+F++ + K + + F Q+ D + + D K
Sbjct: 122 VICPGSLFDRRGGRMGYGGGFYDRFLSGEKAQ---NMKKIGLCFQFQLFDIIEQEDHDVK 178
Query: 189 VDEVI 193
++ ++
Sbjct: 179 MNYIV 183
>UniRef50_A4WE63 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=25; Gammaproteobacteria|Rep: 5-formyltetrahydrofolate
cyclo-ligase - Enterobacter sp. 638
Length = 198
Score = 79.0 bits (186), Expect = 7e-14
Identities = 56/197 (28%), Positives = 99/197 (50%), Gaps = 11/197 (5%)
Query: 1 MSPIKPNPA-KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTE 59
M+ + PA + +R I + LT +++ +Q +++ +S + +AL++S +
Sbjct: 1 MTQLSEVPASRQEIRQFIRKQRRTLTPDQQAHFAQQASARMMAYSPVVMAHTVALFLSFD 60
Query: 60 NEIDTAPLIKHIQARGAAAFVP---QYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQA 116
E+DT PLI+ + G ++P ++ G + LH E + + K I++ D
Sbjct: 61 GELDTQPLIEQLWRAGKKVYLPVLHPFSPGNLLFLHYHPHSELVVNRLK--ITEPKLDVR 118
Query: 117 RDDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQV 176
D L LD++I P VAF R G RLG GGG+YD+ + N + + + V A +CQ
Sbjct: 119 --DVLPLNELDVLITPLVAFDRYGQRLGMGGGFYDRTLQNWQ---QHGLQPVGYAHDCQG 173
Query: 177 VDEVPTNEQDQKVDEVI 193
VD +P + D + V+
Sbjct: 174 VDMLPVEKWDIPLPAVV 190
>UniRef50_Q3AS61 Cluster: 5-formyltetrahydrofolate cyclo-ligase,
putative; n=1; Chlorobium chlorochromatii CaD3|Rep:
5-formyltetrahydrofolate cyclo-ligase, putative -
Chlorobium chlorochromatii (strain CaD3)
Length = 194
Score = 78.2 bits (184), Expect = 1e-13
Identities = 54/189 (28%), Positives = 91/189 (48%), Gaps = 11/189 (5%)
Query: 8 PAKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTE--NEIDTA 65
P+K LR + K AL E+ S + E+V+ + + ++ Y+S E+ T
Sbjct: 6 PSKQALRLAMREKRLALAESERMAMSVAIAEQVVALPMVQEARQVHCYLSIAALGEVSTE 65
Query: 66 PLIKHIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQA-RDDALETG 124
PL++ + A G VP G + L E +MP I + G+ + R +
Sbjct: 66 PLLQALHAMGKKLLVPVVQGKEL----LSVCYEPSMPLR---IGRFGQPEPERAIPADAA 118
Query: 125 GLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNE 184
LD+++ P +AF G RLG+G GYYD+ + L+ T P + +AF+ Q V +P +
Sbjct: 119 QLDVVVLPLLAFDEKGQRLGYGKGYYDRMLERFTLHHVT-PYCIGLAFSLQQVAALPADF 177
Query: 185 QDQKVDEVI 193
D+ +D V+
Sbjct: 178 WDKPLDAVV 186
>UniRef50_A3EWC9 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Leptospirillum sp. Group II UBA|Rep:
5-formyltetrahydrofolate cyclo-ligase - Leptospirillum
sp. Group II UBA
Length = 206
Score = 78.2 bits (184), Expect = 1e-13
Identities = 57/186 (30%), Positives = 94/186 (50%), Gaps = 16/186 (8%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSS--SRIALYMSTENEIDTAPL 67
KA R+ + ++ ++ +K +S ++ +KV+ SW K+S + L++S E DT PL
Sbjct: 21 KAHFRSHLRNLRDSIPDKLRKEKSALIGQKVL--SWVKNSPAKTLHLFLSFGTEPDTHPL 78
Query: 68 IKHIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLD 127
+ + + A VP + + E G + GI + A + G+D
Sbjct: 79 VSALLDKKFALVVPVIREASLVLTSFERGTP--LRPGPFGILE----PAVVHPVAPEGVD 132
Query: 128 LIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQ 187
L PG+ F R G R+G+G GYYD+ + N TAP ++A+AF Q+VD VP +E D
Sbjct: 133 LFFLPGLGFDRRGGRIGYGRGYYDRLLRN-----TTAP-LIALAFQEQIVDRVPLSETDI 186
Query: 188 KVDEVI 193
VD ++
Sbjct: 187 LVDTIL 192
>UniRef50_Q3XWC2 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Enterococcus faecium DO|Rep:
5-formyltetrahydrofolate cyclo-ligase - Enterococcus
faecium DO
Length = 180
Score = 77.4 bits (182), Expect = 2e-13
Identities = 47/184 (25%), Positives = 93/184 (50%), Gaps = 12/184 (6%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQS-QIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLI 68
K LR + K+ L KK++ Q +Y+++ ++KS+ I +S E E+DT P+I
Sbjct: 5 KVRLRRKGIEKLKNLAKSGKKKEKEQRIYKQLFASEYWKSAKVIGTTLSNEFELDTQPVI 64
Query: 69 KHIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDL 128
+ + VP+ R +M E ++ + ++ G+ + ++ + +DL
Sbjct: 65 QRAEKEQKKIVVPKTLPKR-QMAFYEMDEQSVLVRSSFGVLEPQSEKLYLPEM----IDL 119
Query: 129 IIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQK 188
+I PG+ ++R+G R+G GGGYYD+++ N K ++ F Q+ ++ DQK
Sbjct: 120 LIVPGIIYNRAGYRIGFGGGYYDRYLNNFH------KKTCSLVFREQLNEQWQPESFDQK 173
Query: 189 VDEV 192
+ ++
Sbjct: 174 IQQL 177
>UniRef50_Q1WUH7 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Lactobacillus salivarius subsp. salivarius
UCC118|Rep: 5-formyltetrahydrofolate cyclo-ligase -
Lactobacillus salivarius subsp. salivarius (strain
UCC118)
Length = 182
Score = 77.4 bits (182), Expect = 2e-13
Identities = 46/152 (30%), Positives = 84/152 (55%), Gaps = 7/152 (4%)
Query: 10 KALLRNEIAAKIAALTNE-EKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLI 68
K +N+I K+ L+ EKK +Y+++ + ++ + +A+ +S + E+DT P+I
Sbjct: 6 KEFRKNQIQ-KLQKLSKTWEKKLDELNLYKELFKTTEWEKADNVAITLSEDFELDTFPII 64
Query: 69 KHIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDL 128
Q + VP+ RM M +E + + +TK G+ + ++ + +DL
Sbjct: 65 STAQQQNKKVLVPKTFPNRM-MEFVELTPDVKIVRTKFGVLE----PESENYVNKENIDL 119
Query: 129 IIAPGVAFSRSGDRLGHGGGYYDKFITNLRLN 160
II PG+AF+ +G RLG GGG+YDK++++ R N
Sbjct: 120 IIVPGLAFAENGARLGFGGGFYDKYLSDYRGN 151
>UniRef50_A5KR22 Cluster: Putative uncharacterized protein; n=1;
Ruminococcus torques ATCC 27756|Rep: Putative
uncharacterized protein - Ruminococcus torques ATCC
27756
Length = 194
Score = 77.4 bits (182), Expect = 2e-13
Identities = 52/181 (28%), Positives = 89/181 (49%), Gaps = 9/181 (4%)
Query: 13 LRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQ 72
+R + A AA++ +E+ +I+ ++ + Y+ + + Y S +E+ T +I+
Sbjct: 7 IRKMMTALRAAMSEKERAEAGRIIAARLFSSKVYEDAGTVCCYASFGSEVPTEEIIEESL 66
Query: 73 ARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLIIAP 132
RG A VP+ G + +M + HGI + + R+ + G L+I P
Sbjct: 67 RRGKCAAVPKVTG-KQKMKFALIHSMADLKAGFHGIPEP-ESWCREIP-KCGSKLLVIVP 123
Query: 133 GVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQKVDEV 192
GV F R+G+R+G+GGGYYD + L K V VAF+ Q V+++ D VD +
Sbjct: 124 GVVFDRAGNRIGYGGGYYDSY-----LKQADCIK-VGVAFDFQCVEQIVPEVHDVPVDYI 177
Query: 193 I 193
I
Sbjct: 178 I 178
>UniRef50_Q9FYA5 Cluster: 5-formyltetrahydrofolate cyclo-ligase-like
protein; n=10; Magnoliophyta|Rep:
5-formyltetrahydrofolate cyclo-ligase-like protein -
Arabidopsis thaliana (Mouse-ear cress)
Length = 287
Score = 77.4 bits (182), Expect = 2e-13
Identities = 53/204 (25%), Positives = 100/204 (49%), Gaps = 22/204 (10%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTE--NEIDTAPL 67
K ++R+ + + A+ + +Q + + + V+ W+KS + Y+S + NE+DT+ +
Sbjct: 18 KRVVRSTVRKSLKAMDPSLRTQQDEAIQKTVLEAPWFKSCKGLCAYISCKSLNEVDTSKI 77
Query: 68 IKHIQARGAA-----AFVP--QYAGGRMRMLHLETGDEQTMPKTK----HGISQHGKDQA 116
+ I + +VP + MRMLH+ ++ + G D
Sbjct: 78 LSEILQHPDSNTQKKLYVPWVEDKNSNMRMLHISHMEDLVANSMNILEPAPVDAQGND-- 135
Query: 117 RDDALETGG-LDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETA----PKIVAVA 171
R+D L+ +DL I PG+AF R G RLG GGGYYD F+ + + P +VA++
Sbjct: 136 REDVLQADEPIDLFILPGLAFDRCGRRLGRGGGYYDTFLKRYQDRAKEKGWRYPLMVALS 195
Query: 172 FNCQVVDE--VPTNEQDQKVDEVI 193
++ Q++++ +P D +D ++
Sbjct: 196 YSPQILEDGSIPVTPNDVLIDALV 219
>UniRef50_Q81LX0 Cluster: 5-formyltetrahydrofolate cyclo-ligase
family protein; n=11; Bacillus cereus group|Rep:
5-formyltetrahydrofolate cyclo-ligase family protein -
Bacillus anthracis
Length = 192
Score = 77.0 bits (181), Expect = 3e-13
Identities = 48/185 (25%), Positives = 93/185 (50%), Gaps = 10/185 (5%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQS-QIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLI 68
K LR +I + +L+ E S QIV+ W ++ + I + +S ENE++T P+I
Sbjct: 5 KLRLRKQIIEHMNSLSKERYTTLSEQIVFSLYEQKEWAEAKT-IGITLSMENEVNTYPII 63
Query: 69 KHIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDL 128
+ G VP+ M + + + + + A + + +DL
Sbjct: 64 EKAWKEGKRVVVPKCNKETRTMSFRQISNFDQLETVYMNLRE--PIPALTEEVNADEIDL 121
Query: 129 IIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQK 188
I PGVA++ G+R+G+GGGYYD+++ + + K +++A++ Q+V+ +P D+
Sbjct: 122 QIVPGVAYTERGERIGYGGGYYDRYLVHYK------GKTLSLAYSFQMVEHIPVEPFDKN 175
Query: 189 VDEVI 193
V+++I
Sbjct: 176 VEKII 180
>UniRef50_A1IE08 Cluster: 5-formyltetrahydrofolate cyclo-ligase
family protein; n=1; Candidatus Desulfococcus oleovorans
Hxd3|Rep: 5-formyltetrahydrofolate cyclo-ligase family
protein - Candidatus Desulfococcus oleovorans Hxd3
Length = 195
Score = 77.0 bits (181), Expect = 3e-13
Identities = 53/181 (29%), Positives = 89/181 (49%), Gaps = 13/181 (7%)
Query: 17 IAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQARGA 76
+ KI A T +E ++S+ + ++ + + + + +Y++ E+DT +IKH +
Sbjct: 15 VVKKIGAFTKDELSQKSRQILTRLFGFANFMEARVVFIYLNKPGEVDTRSIIKHCFSCNK 74
Query: 77 AAFVPQYAGGR--MRMLHLE--TGDEQTMPKTKHGISQHGKDQARDDALETGGLDLIIAP 132
A VP R +R+L L + D T P+ + D R + +++ I P
Sbjct: 75 VAVVPYDDTNRKDLRLLKLNDPSADFITGPR-----GETVADPNRCRVVPIDSVEIAIIP 129
Query: 133 GVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQKVDEV 192
G+ F G R+G G GYYDK I L P T K V++AF Q++ +VP D+ VD +
Sbjct: 130 GLVFDEKGARIGLGTGYYDKLIPKL---PATTRK-VSLAFEDQIIAQVPKGSIDRHVDII 185
Query: 193 I 193
I
Sbjct: 186 I 186
>UniRef50_Q67Q66 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Symbiobacterium thermophilum|Rep:
5-formyltetrahydrofolate cyclo-ligase - Symbiobacterium
thermophilum
Length = 197
Score = 76.6 bits (180), Expect = 4e-13
Identities = 50/183 (27%), Positives = 83/183 (45%), Gaps = 9/183 (4%)
Query: 9 AKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLI 68
+K LR + A AL E+ R S V+ + + + LY+ E+DTA L
Sbjct: 4 SKQELRRRMIAARQALDPAERARLSGRAQRAVLAAPEWARARTVLLYIPVRGEVDTAALA 63
Query: 69 KHIQARGAAAFVPQYAGGRMRM-LHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLD 127
+ G +P+ + LH G + + + +GI + D ++D +D
Sbjct: 64 AAGRQAGKRLLLPRVERAERGLRLHRWDGTPEQLVRGAYGIPEPRPDLPQEDPR---AVD 120
Query: 128 LIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQ 187
L++ PGVAF R G RLG+GGGYYD+ + L + + + Q+V+ +P D
Sbjct: 121 LVVVPGVAFDRRGRRLGYGGGYYDRLLPQL-----ARAAAIGLGYGFQLVERLPAEAHDV 175
Query: 188 KVD 190
+D
Sbjct: 176 PLD 178
>UniRef50_P44905 Cluster: Uncharacterized protein HI0858; n=16;
Gammaproteobacteria|Rep: Uncharacterized protein HI0858
- Haemophilus influenzae
Length = 187
Score = 76.6 bits (180), Expect = 4e-13
Identities = 52/182 (28%), Positives = 91/182 (50%), Gaps = 6/182 (3%)
Query: 13 LRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQ 72
+R EI A LT ++ + Q V + +N + + IALY S + EI T LI+ +
Sbjct: 9 IRTEIRKIRANLTALQQHQAEQSVTQHALNLIEQRQAKNIALYFSFDGEISTKALIQSLW 68
Query: 73 ARGAAAFVPQ-YAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLIIA 131
+ ++P + + +L L + M + + GI + + + L LD++
Sbjct: 69 MQNKNVYLPVLHPFTKHYLLFLRYLPDTPMKQNQFGIWEPKLNV--QNVLPLNELDILFT 126
Query: 132 PGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQKVDE 191
P VAF + G+RLG GGG+YD+ + N + N P V +A+ CQ V+ +PT D + +
Sbjct: 127 PLVAFDKKGNRLGMGGGFYDRTLQNWQ-NKSFIP--VGLAYQCQQVENLPTEHWDVPLFD 183
Query: 192 VI 193
++
Sbjct: 184 IL 185
>UniRef50_Q0HZ35 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=10; Gammaproteobacteria|Rep: 5-formyltetrahydrofolate
cyclo-ligase - Shewanella sp. (strain MR-7)
Length = 228
Score = 76.2 bits (179), Expect = 5e-13
Identities = 52/197 (26%), Positives = 96/197 (48%), Gaps = 10/197 (5%)
Query: 1 MSP-IKPNPAKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTE 59
+SP + P ++A LR +I +L E + S +++ ++ +ALY++ +
Sbjct: 30 LSPNLSPTLSRAELRKQIRLARRSLPIEVQTEASLAAGLRMLEKLSALNAQHVALYLTHD 89
Query: 60 NEIDTAPLIKHIQARGAAAFVPQ---YAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQA 116
E+ TAPLI+ + +G ++P+ + G++ LH + M + GI + D
Sbjct: 90 GELATAPLIEALWQQGIQTYLPRLHPFNAGQLLFLHYHA--DSPMQPNQFGILEPKLDVR 147
Query: 117 RDDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQV 176
+E +D+++ P VAF G+R+G GGGYYD+ + N + P + A +CQ
Sbjct: 148 AVMPIEH--IDVVVTPLVAFDIKGNRMGMGGGYYDRTLANWHAKGKPLP--MGYAHDCQQ 203
Query: 177 VDEVPTNEQDQKVDEVI 193
V +P D + +I
Sbjct: 204 VTTLPCEHWDVPLPAII 220
>UniRef50_Q1YVJ4 Cluster: 5-formyltetrahydrofolate cyclo-ligase
family protein; n=1; gamma proteobacterium HTCC2207|Rep:
5-formyltetrahydrofolate cyclo-ligase family protein -
gamma proteobacterium HTCC2207
Length = 195
Score = 75.8 bits (178), Expect = 6e-13
Identities = 51/178 (28%), Positives = 88/178 (49%), Gaps = 10/178 (5%)
Query: 13 LRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQ 72
+R+ I K AL +++ S+ + + + +++ + RI +Y++ + EID + ++
Sbjct: 6 IRSNIREKRRALNPSQQRTASEQLAKLLCRQDFFQRAKRIGIYLANDGEIDPSAIVTAAF 65
Query: 73 ARGAAAFVPQYAGGRMRMLHL---ETGDEQTMPKTKHGISQHGKDQARDDALETG-GLDL 128
A F+P + LH + GD T+ K + GI + Q R A+ LDL
Sbjct: 66 RAKKACFLPLIDPLKANSLHFAEYQLGD--TLHKNRFGILE---PQFRSTAITPPWSLDL 120
Query: 129 IIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQD 186
I+ P VAF R+G+RLG GGG+YD+ + P K++ +A CQ V + D
Sbjct: 121 ILLPLVAFDRAGNRLGMGGGFYDRTLAPRPGKPNNV-KLIGLAHQCQEVSGLSPQSWD 177
>UniRef50_Q011H2 Cluster: Predicted methyltransferase; n=2;
Ostreococcus|Rep: Predicted methyltransferase -
Ostreococcus tauri
Length = 515
Score = 75.8 bits (178), Expect = 6e-13
Identities = 58/168 (34%), Positives = 87/168 (51%), Gaps = 23/168 (13%)
Query: 47 KSSSRIALYMSTEN--EIDTAPLIKHIQARG-AAAFVPQYAGGR---MRMLHLETGDEQT 100
+ + R+A Y+++E E T+ ++ A G FVP + MRML +E E
Sbjct: 24 RDARRVAAYLASERLRECATSGFVRRALASGNTRVFVPLVSDASTSSMRMLEIED-PETD 82
Query: 101 MPKTKHGISQHGKDQA----RDDALE----TGGLDLIIAPGVAFSRSGDRLGHGGGYYDK 152
+ + +G+ + +A R DALE G LD+II PG AF G RLG GGGYYD
Sbjct: 83 VERGAYGLPEPRATRADGSRRVDALEDIETVGALDVIIVPGFAFGEDGRRLGRGGGYYDA 142
Query: 153 FITN-----LRLNPETAPKIVAVAFNCQVVDE--VPTNEQDQKVDEVI 193
F+ +R+N + P +VA+A+ CQ+ VP + D+ VD V+
Sbjct: 143 FLARYADACVRVN-ASPPLVVALAYECQICPPGVVPIDAHDRIVDVVV 189
>UniRef50_Q8RF22 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=3; Fusobacterium nucleatum|Rep:
5-formyltetrahydrofolate cyclo-ligase - Fusobacterium
nucleatum subsp. nucleatum
Length = 181
Score = 75.4 bits (177), Expect = 9e-13
Identities = 48/162 (29%), Positives = 86/162 (53%), Gaps = 15/162 (9%)
Query: 33 SQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQARGAAAFVPQYAGGRMRMLH 92
S ++EK++ + +K+ + YM +NE+ T + I+ G +P+ + M+
Sbjct: 27 SDKIFEKLLQNEDFKNVKTVMSYMDFKNEVKTDRINTFIKNSGKILVLPKVVD-KETMIV 85
Query: 93 LETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDK 152
+E K ++ +S G + + + G +D+II PGVAF R +R+G G GYYD+
Sbjct: 86 IED-------KNQYIVSPFGNKEPDGEEYK-GSIDVIITPGVAFDRDKNRVGFGRGYYDR 137
Query: 153 FITNLRLNPETAPKIVAVAFNCQVVDE-VPTNEQDQKVDEVI 193
F + K +A+AF Q++DE + T++ D+KVD +I
Sbjct: 138 FFVK-----QPNAKKIAIAFEKQIIDEGIETDKYDKKVDILI 174
>UniRef50_Q74E28 Cluster: 5-formyltetrahydrofolate cyclo-ligase
family protein; n=2; Geobacter|Rep:
5-formyltetrahydrofolate cyclo-ligase family protein -
Geobacter sulfurreducens
Length = 187
Score = 75.4 bits (177), Expect = 9e-13
Identities = 50/187 (26%), Positives = 90/187 (48%), Gaps = 15/187 (8%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 69
K +LR + A +L E + S+ + + ++++ IALY E+DT+ +++
Sbjct: 3 KRVLRQSMLALRKSLAPVEARWASEAIQRSFVESEGFRNARVIALYAPIRGEVDTSDVLR 62
Query: 70 HIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQH---GKDQARDDALETGGL 126
+G +P G +R + E D + GI + GK A D A
Sbjct: 63 LALDQGKTVLLPAVCGDELRFI--EVTDPAGLRSGSFGIPEPCLTGKAVAPDCA------ 114
Query: 127 DLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQD 186
D+I+ PGVAF +G R+G+G G+YD+ + +L E ++V ++ Q+VDE+ D
Sbjct: 115 DIIVVPGVAFDLAGHRIGYGKGFYDRALHHL----EGTGRLVGFCYDFQLVDEIRGEPHD 170
Query: 187 QKVDEVI 193
+D ++
Sbjct: 171 VALDLIV 177
>UniRef50_Q4K404 Cluster: 5-formyltetrahydrofolate cyclo-ligase
family protein; n=16; Pseudomonadaceae|Rep:
5-formyltetrahydrofolate cyclo-ligase family protein -
Pseudomonas fluorescens (strain Pf-5 / ATCC BAA-477)
Length = 230
Score = 75.4 bits (177), Expect = 9e-13
Identities = 50/179 (27%), Positives = 91/179 (50%), Gaps = 5/179 (2%)
Query: 5 KPNP-AKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEID 63
+P P ++ LR + AL+ E+++ + +Y ++ ++ + ++LY+ T+ EID
Sbjct: 32 EPAPLSRPQLRRMLRKARRALSPAEQRQAALGLYRQLAQDPVFRRARHLSLYLPTDGEID 91
Query: 64 TAPLIKHIQARGAAAFVPQY-AGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALE 122
L++ Q RG A ++P A R +M+ +T+ + I + + AR +
Sbjct: 92 PRLLLRAAQRRGKATYLPVLSAWPRTKMVFQRVLPGETLRPNRFRILEPRVNCARQR--K 149
Query: 123 TGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNL-RLNPETAPKIVAVAFNCQVVDEV 180
LDL++ P V F G RLG GGG+YD+ + L R PK++ +A CQ V ++
Sbjct: 150 VWALDLVLLPLVGFDEEGGRLGMGGGFYDRSLAYLARRQNWRKPKLLGLAHECQKVGKL 208
>UniRef50_A6BE49 Cluster: Putative uncharacterized protein; n=1;
Dorea longicatena DSM 13814|Rep: Putative
uncharacterized protein - Dorea longicatena DSM 13814
Length = 174
Score = 75.4 bits (177), Expect = 9e-13
Identities = 48/158 (30%), Positives = 80/158 (50%), Gaps = 12/158 (7%)
Query: 36 VYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQARGAAAFVPQYAGGRMRMLHLET 95
+ E+VINH + + I Y + E+ T+ +++ G + + P+ G M +E+
Sbjct: 13 ITERVINHPRFLEETDIYCYANYNGEVGTSSIMEEAWKLGKSVWFPRIEGSEMNFYLVES 72
Query: 96 GDEQTMPKTKHGISQHGKDQARDDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFIT 155
D+ + +GI + D D E G L+I PGVAF R+G+GGG+YDK+
Sbjct: 73 KDD--LQPGAYGILEPTGDHIADG--EDG---LLIMPGVAFDEECHRIGYGGGFYDKY-- 123
Query: 156 NLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQKVDEVI 193
L +P +A+AF Q+ E+P E D K ++V+
Sbjct: 124 -LEKHPNL--HAIAIAFELQMYRELPFEEHDIKPEKVV 158
>UniRef50_Q5KX52 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=2; Geobacillus|Rep: 5-formyltetrahydrofolate
cyclo-ligase - Geobacillus kaustophilus
Length = 190
Score = 74.9 bits (176), Expect = 1e-12
Identities = 46/180 (25%), Positives = 87/180 (48%), Gaps = 8/180 (4%)
Query: 14 RNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQA 73
R + ++ L EK+ + + + ++++ IA+ +S E E++T P+++
Sbjct: 9 RQRMLNQLRQLKAAEKEMYDRQIAAHLYRWPLWQTARTIAMTVSRETEVNTLPIMEQAWR 68
Query: 74 RGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLIIAPG 133
G VP+ M + K G+ + + Q ++ DLII PG
Sbjct: 69 EGKTIGVPKCDPRAKTMSFRRLESFAQLEKAYAGLFEPIEKQTTP--IDRDEFDLIIVPG 126
Query: 134 VAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQKVDEVI 193
V F+++G R+G+GGGYYD+++ P + A+A++ QV+D++P E D V +I
Sbjct: 127 VCFAKTGYRIGYGGGYYDRYL------PGASAVTAALAYSFQVMDDIPAEEHDVPVKFII 180
>UniRef50_Q3SFD5 Cluster: 5-formyltetrahydrofolate cyclo-ligase
family protein; n=1; Thiobacillus denitrificans ATCC
25259|Rep: 5-formyltetrahydrofolate cyclo-ligase family
protein - Thiobacillus denitrificans (strain ATCC 25259)
Length = 199
Score = 74.9 bits (176), Expect = 1e-12
Identities = 54/187 (28%), Positives = 82/187 (43%), Gaps = 9/187 (4%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 69
K LR ++ A AL ++ ++ + H + RI Y+ E D PL+
Sbjct: 3 KYALRRQLKAARNALRPTARRHAARGALRLALRHGLLLRAQRIGFYLPQGGEFDAHPLLD 62
Query: 70 HIQARGAAAFVPQYA--GGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLD 127
H A A ++P G MR L M ++GI + + L LD
Sbjct: 63 HALAMRRACYLPVVPRRGRVMRFGRLHRATR--MSPNRYGIPEPLDPRP----LRARELD 116
Query: 128 LIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPE-TAPKIVAVAFNCQVVDEVPTNEQD 186
L++ P V F G RLG GGGYYD + ++ P++V VA+ CQ VD +P + D
Sbjct: 117 LLLMPLVGFDTDGYRLGMGGGYYDATLAFMQHRRHWRKPRLVGVAYECQRVDTLPHDPWD 176
Query: 187 QKVDEVI 193
+D V+
Sbjct: 177 MPLDAVL 183
>UniRef50_Q0VL96 Cluster: 5-formyltetrahydrofolate cyclo-ligase
family protein; n=1; Alcanivorax borkumensis SK2|Rep:
5-formyltetrahydrofolate cyclo-ligase family protein -
Alcanivorax borkumensis (strain SK2 / ATCC 700651 / DSM
11573)
Length = 193
Score = 74.5 bits (175), Expect = 1e-12
Identities = 52/186 (27%), Positives = 90/186 (48%), Gaps = 7/186 (3%)
Query: 13 LRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQ 72
LR ++ + L+ +++R S + ++ + +A+Y+ + E+D P + H +
Sbjct: 9 LRRQLRQRRRTLSKGQRRRASIRFGPALARAIQHRPARHVAIYLPNDGELDLQPALHHPR 68
Query: 73 ARGAAAFVPQYAGGRMRMLHLETGDEQ-TMPKTKHGISQHGKDQARDDALETGGLDLIIA 131
+ A ++P R+ L M +GI Q + R AL LD+II
Sbjct: 69 FQQATTYLPFVDPLRLGYLQFRLWHHHHPMRPNAYGI-QEPAVRYRGRAL--WALDVIIL 125
Query: 132 PGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVD--EVPTNEQDQKV 189
P VAF +G RLG GGGYYD+ + L P P+++A ++ Q ++ E+P DQ V
Sbjct: 126 PAVAFDEAGYRLGMGGGYYDRTLEQLTRYPR-RPRLIAAGYDFQKMEQGELPVAPWDQPV 184
Query: 190 DEVIFA 195
D ++ A
Sbjct: 185 DCIVTA 190
>UniRef50_Q55ZD6 Cluster: Putative uncharacterized protein; n=1;
Filobasidiella neoformans|Rep: Putative uncharacterized
protein - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 234
Score = 74.5 bits (175), Expect = 1e-12
Identities = 58/216 (26%), Positives = 106/216 (49%), Gaps = 33/216 (15%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMS-TENEIDTAPLI 68
KA LR + + +++ E +QS+ V+ +++ +++K ++ + Y+S + E+ T ++
Sbjct: 8 KATLRKTMLRTLKGMSDSEIDKQSRDVFRTLLDQNFFKKANSVGCYLSMAQGELRTDLIV 67
Query: 69 KHIQARGAAAFVPQY-------------------AGGRMRMLHL-ETGDEQTMPKTKHGI 108
H+ RG + + P A MRML L T D + P + GI
Sbjct: 68 DHLLKRGTSLYTPYIPAPPSRTHNPSAPSLSSPSAEQDMRMLRLYSTQDLENCPLDRWGI 127
Query: 109 SQHGKDQA------RDDALETGG--LDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLN 160
G ++ R+DA+ +DLI+ PGVAF +RLG G YYD+F+ + +
Sbjct: 128 VDPGVERRDMDKSFREDAMSPKAPPMDLILIPGVAFDEECNRLGRGKAYYDRFLQSY-TS 186
Query: 161 PETAPKIVAVAFNCQVV---DEVPTNEQDQKVDEVI 193
P ++A+A Q++ + VPT + D ++D +I
Sbjct: 187 TRPRPLLMAIALEPQILPHGERVPTWDWDFQLDGII 222
>UniRef50_A6NRP0 Cluster: Putative uncharacterized protein; n=1;
Bacteroides capillosus ATCC 29799|Rep: Putative
uncharacterized protein - Bacteroides capillosus ATCC
29799
Length = 186
Score = 74.1 bits (174), Expect = 2e-12
Identities = 41/149 (27%), Positives = 77/149 (51%), Gaps = 4/149 (2%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 69
KA LR + A+++A++ EE++ I++ + + ++ R+ L+ E DTA LI
Sbjct: 10 KAALRRVVRARLSAMSPEEREESDGILFRRFLALPEVAAADRVLLFYGMGAEPDTARLIP 69
Query: 70 HIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLI 129
+ G +P+ G + ++ + + ++G+ + G+D + +DLI
Sbjct: 70 VLLDMGKQVLLPRCLPGH-GLEARRVAEKSVLIRHRYGMLEPGEDCP---VVPREAIDLI 125
Query: 130 IAPGVAFSRSGDRLGHGGGYYDKFITNLR 158
+ PG+ F R G RLG GGGYYD+++ R
Sbjct: 126 LVPGLCFDRLGYRLGQGGGYYDRYLAGYR 154
>UniRef50_Q0KWG0 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=4; Shewanella baltica|Rep: 5-formyltetrahydrofolate
cyclo-ligase - Shewanella baltica OS195
Length = 235
Score = 73.7 bits (173), Expect = 3e-12
Identities = 49/184 (26%), Positives = 90/184 (48%), Gaps = 9/184 (4%)
Query: 13 LRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQ 72
LR I +L+ E+ + S +++++ +++ +ALY++ + E+ T PLI +
Sbjct: 50 LRKSIRTARKSLSETEQIQASLSASQRMLDALQAQNAQHVALYLTHDGELATPPLIAALW 109
Query: 73 ARGAAAFVPQ---YAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLI 129
G ++P+ + G++ LH + M + GI + D + LD++
Sbjct: 110 QLGIRTYLPRLHPFNAGQLLFLHYSA--DTPMQANQFGILEPKLDVRA--IIPVTELDVV 165
Query: 130 IAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQKV 189
I P VAF G+R+G GGGYYD+ + N +L + P + A +CQ V +P D +
Sbjct: 166 ITPLVAFDLMGNRMGMGGGYYDRTLANWQLKGKPLP--MGYAHDCQQVVSLPCEHWDVPL 223
Query: 190 DEVI 193
+I
Sbjct: 224 PFII 227
>UniRef50_A6L8H7 Cluster: Putative 5-formyltetrahydrofolate
cyclo-ligase; n=2; Parabacteroides|Rep: Putative
5-formyltetrahydrofolate cyclo-ligase - Parabacteroides
distasonis (strain ATCC 8503 / DSM 20701 / NCTC11152)
Length = 184
Score = 73.7 bits (173), Expect = 3e-12
Identities = 56/185 (30%), Positives = 91/185 (49%), Gaps = 12/185 (6%)
Query: 9 AKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLI 68
AK LR ++A++ + S + +++ ++++S IALY + E+ TA I
Sbjct: 6 AKQALRKDMASRKKEYSRITLCELSDKIMDRLEQTELFQAASCIALYHAIPGEVQTAGFI 65
Query: 69 KHIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDL 128
+ + +P G +R+L E G E P GI + D E +DL
Sbjct: 66 EKWYQK-KKLLLPLIVGDDLRLLLYE-GPESLKPGP-FGILEPKADGIEVPKNE---IDL 119
Query: 129 IIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQK 188
II PGVAF + +R+G G G+YD+ ++ L APK V + F Q++ +VP D+K
Sbjct: 120 IIVPGVAFDKDKNRMGRGRGFYDRLLSTL-----NAPK-VGICFGFQMIPQVPVEPLDKK 173
Query: 189 VDEVI 193
+D VI
Sbjct: 174 MDYVI 178
>UniRef50_Q8DC92 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=5; Vibrio|Rep: 5-formyltetrahydrofolate cyclo-ligase -
Vibrio vulnificus
Length = 199
Score = 73.3 bits (172), Expect = 3e-12
Identities = 44/148 (29%), Positives = 76/148 (51%), Gaps = 8/148 (5%)
Query: 49 SSRIALYMSTENEIDTAPLIKHIQARGAAAFVP---QYAGGRMRMLHLETGDEQTMPKTK 105
+ IALY+S + E+DT PLI+ + G ++P ++ G++ LH + + +
Sbjct: 45 AQHIALYLSADGELDTKPLIEWLWELGKQVYLPVIHPFSKGQLLFLHYHRHTD--LIYNR 102
Query: 106 HGISQHGKDQARDDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAP 165
+GI + D+ + LDLI P VAF +G RLG GGGYYD+ +
Sbjct: 103 YGILEPKLDKRH--IIPLAELDLICTPLVAFDSTGQRLGMGGGYYDRTLERW-FRTGLGA 159
Query: 166 KIVAVAFNCQVVDEVPTNEQDQKVDEVI 193
K + +A +CQ V+++P D + +++
Sbjct: 160 KPIGIAHDCQHVEQLPCEVWDIPLPKIV 187
>UniRef50_Q5HNZ9 Cluster: 5-formyltetrahydrofolate cyclo-ligase
family protein; n=4; Staphylococcus|Rep:
5-formyltetrahydrofolate cyclo-ligase family protein -
Staphylococcus epidermidis (strain ATCC 35984 / RP62A)
Length = 183
Score = 73.3 bits (172), Expect = 3e-12
Identities = 42/148 (28%), Positives = 72/148 (48%), Gaps = 5/148 (3%)
Query: 13 LRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQ 72
LR I K+ + E+K + + +K+ Y+ ++ I +S +E++T P+I H
Sbjct: 6 LRRNIIKKMKSYDKEQKYLADEWLAKKLYQSEAYRKANTIGFVLSMPHEVNTYPIITHSL 65
Query: 73 ARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLIIAP 132
FVP+ + M + + + K GI H T +DL++ P
Sbjct: 66 NNNKKIFVPETNYQQQDMTFKQLLSIEDIEKDSKGI-YHSISPVGT----TNKMDLVVVP 120
Query: 133 GVAFSRSGDRLGHGGGYYDKFITNLRLN 160
GVAF + G R+G+GGGYYD+F++ + N
Sbjct: 121 GVAFDKLGYRIGYGGGYYDRFLSQHKCN 148
>UniRef50_Q180V5 Cluster: Putative 5-formyltetrahydrofolate
cyclo-ligase; n=2; Clostridium difficile|Rep: Putative
5-formyltetrahydrofolate cyclo-ligase - Clostridium
difficile (strain 630)
Length = 189
Score = 72.9 bits (171), Expect = 5e-12
Identities = 42/162 (25%), Positives = 84/162 (51%), Gaps = 8/162 (4%)
Query: 33 SQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQARGAAAFVPQYAGGRMRMLH 92
S ++ EK++ ++++ I LY++ NE+ T LIK + + P ++
Sbjct: 25 SNLITEKLLQMEDIRNATNIMLYLNFNNEVQTDNLIKKLLSLKKIVSSPITIKENHTLIP 84
Query: 93 LETGD-EQTMPKTKHGISQHGKDQARDDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYD 151
+ D ++ + +GI + + + ++ LD++I P VA+ RLG+GGG+YD
Sbjct: 85 TQITDLKEGLRIGAYGIREPNE---KSPTIDIKALDVVIVPAVAYDIHCYRLGYGGGFYD 141
Query: 152 KFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQKVDEVI 193
+F+ NLR + T + +AF+ Q+ D +P D ++D ++
Sbjct: 142 RFLENLRKDAIT----IGIAFDFQIFDSIPKETHDAQLDYIV 179
>UniRef50_A6QH93 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=12; Staphylococcus aureus|Rep:
5-formyltetrahydrofolate cyclo-ligase - Staphylococcus
aureus (strain Newman)
Length = 197
Score = 72.9 bits (171), Expect = 5e-12
Identities = 51/193 (26%), Positives = 87/193 (45%), Gaps = 12/193 (6%)
Query: 1 MSPIKPNPAKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTEN 60
++ + N K +R I K+ EK++ + + YK ++ IAL +S +
Sbjct: 12 LNKVGDNVTKNEIRKYILHKMKNFNKAEKRKADTWLRNQFFATEEYKEANAIALVLSFNH 71
Query: 61 EIDTAPLIKHIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDA 120
E+DT +I+ FVP +M L+ + ++ + G
Sbjct: 72 EVDTFSIIEQALMDHKRIFVP-----KMDYLNHQMTFKEIFNLKDIDVDNKGIYYPTSKG 126
Query: 121 LETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEV 180
T LDLI+ PGV F G R+G+GGGYYD+F+ N + K +++ ++ Q+
Sbjct: 127 ETTNNLDLIVVPGVGFQDDGYRIGYGGGYYDRFLANYQ------TKTISLLYDFQITSFE 180
Query: 181 PTNEQDQKVDEVI 193
P DQ VD++I
Sbjct: 181 P-ESFDQPVDKLI 192
>UniRef50_A0W837 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=2; Desulfuromonadales|Rep: 5-formyltetrahydrofolate
cyclo-ligase - Geobacter lovleyi SZ
Length = 197
Score = 72.9 bits (171), Expect = 5e-12
Identities = 51/184 (27%), Positives = 90/184 (48%), Gaps = 9/184 (4%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 69
K LR+++ A A+ + + S ++I+ ++ ++ IALY + EIDT L
Sbjct: 3 KKSLRSDLLAHRRAIDHALWQDASTAAQLRLISLEAFQRAACIALYSPIQREIDTGLLFS 62
Query: 70 HIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLI 129
+++G P G ++ + EQ P GI + + D ALET DLI
Sbjct: 63 KARSKGKRVLYPLVCGATLQFREVNA-PEQCTPGA-FGILEPCR-LGEDHALETA--DLI 117
Query: 130 IAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQKV 189
+ PGVAF G R+G G GYYD+ ++ L+ + +V + + Q+++ +P D ++
Sbjct: 118 VVPGVAFDLQGHRIGFGKGYYDRCLSQLQRH----GVLVGLCHDFQLLERIPAEGHDIRM 173
Query: 190 DEVI 193
+I
Sbjct: 174 QHII 177
>UniRef50_P54491 Cluster: Uncharacterized protein yqgN; n=2;
Bacillus|Rep: Uncharacterized protein yqgN - Bacillus
subtilis
Length = 187
Score = 72.1 bits (169), Expect = 8e-12
Identities = 46/184 (25%), Positives = 93/184 (50%), Gaps = 8/184 (4%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 69
K+ LR + ++AL+NE+ ++++ +Y+ + + ++++ IA+ +S EI T P+I+
Sbjct: 2 KSQLRKKTLEALSALSNEDILQKTERMYKYLFSLPEWQNAGTIAVTISRGLEIPTRPVIE 61
Query: 70 HIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLI 129
G +P+ +M + + G+ + ++ ++ + +DL+
Sbjct: 62 QAWEEGKQVCIPKCHPDTKKMQFRTYQTDDQLETVYAGLLEPVIEKTKE--VNPSQIDLM 119
Query: 130 IAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQKV 189
I PGV F +G R+G GGGYYD++++ E K V++ CQ+ VP D V
Sbjct: 120 IVPGVCFDVNGFRVGFGGGYYDRYLS------EYEGKTVSLLLECQLFAHVPRLPHDIPV 173
Query: 190 DEVI 193
++I
Sbjct: 174 HKLI 177
>UniRef50_Q2B5W6 Cluster: Possible 5-formyltetrahydrofolate
cyclo-ligase; n=1; Bacillus sp. NRRL B-14911|Rep:
Possible 5-formyltetrahydrofolate cyclo-ligase -
Bacillus sp. NRRL B-14911
Length = 175
Score = 71.7 bits (168), Expect = 1e-11
Identities = 45/176 (25%), Positives = 84/176 (47%), Gaps = 8/176 (4%)
Query: 20 KIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQARGAAAF 79
K++ +T +E ++ S + +++ N +K + I + +S E DT +I+ G
Sbjct: 4 KLSEITKQEYEQWSYQLAQRLYNEESWKKADTIGITVSRFPEPDTLQIIRRAWEEGKRVA 63
Query: 80 VPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLIIAPGVAFSRS 139
VP+ +M + +G+ + +A + +E L+I PG+A+
Sbjct: 64 VPKCFPADRKMEFRRLTSFLELESVYYGLLE--PIEALTEKIEPEEFGLMIVPGLAYCSG 121
Query: 140 GDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQKVDEVIFA 195
G RLG GGGYYD+++ +++AF Q+V E+P D+K+D +I A
Sbjct: 122 GLRLGFGGGYYDRWLAGY------GGDTISLAFRMQMVPEMPVEPHDKKIDMIITA 171
>UniRef50_A7H9A8 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=2; Anaeromyxobacter|Rep: 5-formyltetrahydrofolate
cyclo-ligase - Anaeromyxobacter sp. Fw109-5
Length = 205
Score = 71.7 bits (168), Expect = 1e-11
Identities = 48/190 (25%), Positives = 84/190 (44%), Gaps = 9/190 (4%)
Query: 4 IKPNPAKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEID 63
+ P K LR + A +AL ++ +S + +++ ++ + +ALY + E+D
Sbjct: 12 LTPVEEKRALRAAVLAARSALPAADRLERSHAIAQRLEEVPCFRDARTLALYAALGAEVD 71
Query: 64 TAPLIKHIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALET 123
+ + +RG P+ G R+ E + + + A +
Sbjct: 72 ASGIAAGAASRGVLLVYPRIVPGDRRLAFARCAPEALVRGPMGAL----EPPAEAPPVPR 127
Query: 124 GGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTN 183
+D ++ PGVAFS G RLG GGGYYD L P A V +AF+ Q+V +P
Sbjct: 128 DAVDCVLMPGVAFSPDGHRLGRGGGYYD---ATLEAMPRAAR--VGLAFDLQLVPALPAE 182
Query: 184 EQDQKVDEVI 193
D ++D ++
Sbjct: 183 GHDARLDALV 192
>UniRef50_Q1MZK4 Cluster: 5-formyltetrahydrofolate cyclo-ligase
family protein; n=1; Oceanobacter sp. RED65|Rep:
5-formyltetrahydrofolate cyclo-ligase family protein -
Oceanobacter sp. RED65
Length = 239
Score = 71.3 bits (167), Expect = 1e-11
Identities = 41/184 (22%), Positives = 92/184 (50%), Gaps = 5/184 (2%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 69
+ L+R + K +L+++++ + ++ + + ++ +++ + IA+Y++ + E + L +
Sbjct: 53 RQLIRQAMRGKRQSLSDQQQLKHAKAIAKHAMSANFFTRAQTIAIYLANDGEANPVVLAE 112
Query: 70 HIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLI 129
RG +P + L + +P+ K+ ++ + ++ LDL+
Sbjct: 113 KSLYRGKQCVLPILHPTKKGFLQFA---DYRLPRKKNKFGI--EEPISREFVKAQQLDLV 167
Query: 130 IAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQKV 189
P VAF + G RLG GGG+YD+ LR + PK++ +A + Q V+ +P E D +
Sbjct: 168 FMPLVAFDQQGGRLGMGGGFYDRSFEFLRHSTLPKPKLIGLAHSFQQVESLPIEEWDVPM 227
Query: 190 DEVI 193
++
Sbjct: 228 HAIV 231
>UniRef50_A6EYV6 Cluster: 5-formyltetrahydrofolate cyclo-ligase
family protein; n=2; Gammaproteobacteria|Rep:
5-formyltetrahydrofolate cyclo-ligase family protein -
Marinobacter algicola DG893
Length = 216
Score = 71.3 bits (167), Expect = 1e-11
Identities = 49/188 (26%), Positives = 87/188 (46%), Gaps = 7/188 (3%)
Query: 9 AKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLI 68
+++ LR + K +L+ EE++ + + ++ H + +A+Y+ + EID +
Sbjct: 19 SRSNLRKALRKKRRSLSVEEQQIAADQLALNLLKHPDLFRARHVAVYLPNDGEIDPQVYV 78
Query: 69 KHIQARGAAAFVP---QYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGG 125
+ RG ++P GR+ G E T + GI + + +
Sbjct: 79 HVARRRGIQFYLPVLHPVHRGRLVFSPFTNGTELTA--NRFGIPEPPFHKGLERP--PWA 134
Query: 126 LDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQ 185
LD ++ P V F G RLG GGG+YD+ R+ P APK++ +A +CQ V E+P
Sbjct: 135 LDAVLFPLVGFDGFGGRLGMGGGFYDRTFAFTRIRPRLAPKLIGLAHDCQKVLELPLEPW 194
Query: 186 DQKVDEVI 193
D + V+
Sbjct: 195 DIPLHSVV 202
>UniRef50_Q89ZW3 Cluster: Putative 5-formyltetrahydrofolate
cyclo-ligase; n=6; Bacteroides|Rep: Putative
5-formyltetrahydrofolate cyclo-ligase - Bacteroides
thetaiotaomicron
Length = 196
Score = 70.9 bits (166), Expect = 2e-11
Identities = 54/184 (29%), Positives = 87/184 (47%), Gaps = 12/184 (6%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 69
K L + + KI ++ +K QS + + H +++++ + LY S ++E+DT I+
Sbjct: 5 KELRKLMASLKIRHASSTLQKLQSAKILAALEAHPAFRAATTVLLYHSLKDEVDTHAFIR 64
Query: 70 HIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLI 129
+ +P G + L L TG E T +GI + + D A +D I
Sbjct: 65 K-WSNEKRILLPVVVGDELE-LRLYTGPEDMATGT-YGIEEPVGETFTDYA----DIDFI 117
Query: 130 IAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQKV 189
PGVAF R G+RLG G GYYD+ + + A + F Q+V+EVP D +
Sbjct: 118 AVPGVAFDRKGNRLGRGKGYYDRLLPRI-----PAAYKAGICFPFQIVEEVPAEAFDICM 172
Query: 190 DEVI 193
D +I
Sbjct: 173 DIII 176
>UniRef50_Q7P0R7 Cluster: Probable 5-formyltetrahydrofolate
cyclo-ligase; n=1; Chromobacterium violaceum|Rep:
Probable 5-formyltetrahydrofolate cyclo-ligase -
Chromobacterium violaceum
Length = 203
Score = 70.9 bits (166), Expect = 2e-11
Identities = 44/147 (29%), Positives = 75/147 (51%), Gaps = 9/147 (6%)
Query: 47 KSSSRIALYMSTENEIDTAPLIKHIQARGAAAFVPQYA--GGRMRMLHLETGDEQTMPKT 104
K R+ Y++ +E+D A ++ RGAA ++PQ G R+ L+ D +
Sbjct: 45 KRGKRVGGYLAAGSELDLAEVMNAALWRGAAVYLPQIPKRGRRLWFTRLDAADRWYL-HP 103
Query: 105 KHGISQHGKDQARDDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETA 164
++ I ++ + R + L D++ P + R G R+G GGG+YD + R + +
Sbjct: 104 RYRILEYAGARLRAERL-----DVVFVPLLGVDRDGYRMGQGGGFYDSTLAFRRRHALSG 158
Query: 165 -PKIVAVAFNCQVVDEVPTNEQDQKVD 190
P +V VAF+CQ+VD VP D ++D
Sbjct: 159 KPLLVGVAFDCQLVDAVPREAWDVRLD 185
>UniRef50_Q03RP0 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Lactobacillus brevis ATCC 367|Rep:
5-formyltetrahydrofolate cyclo-ligase - Lactobacillus
brevis (strain ATCC 367 / JCM 1170)
Length = 182
Score = 70.9 bits (166), Expect = 2e-11
Identities = 53/186 (28%), Positives = 90/186 (48%), Gaps = 15/186 (8%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 69
K LR + + A+ ++++ ++ ++ ++ + ++ + +A +S + E+ TAP+I
Sbjct: 4 KKHLRQQTIQALMAMPADQRQHATRDLHHQLWSSLAWQQAKTVATTISGDFELATAPIID 63
Query: 70 HIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDAL-ETGGLDL 128
QA G VP R H+ D QT T S G + + A+ DL
Sbjct: 64 RAQAEGKTIAVPTTLPNRQMAFHVV--DNQTNFAT----SPFGLQEPTNGAIIAPATFDL 117
Query: 129 IIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVV--DEVPTNEQD 186
+I PG+ F+ SG+RLG GGGYYD+++ +T VA+A Q V P E D
Sbjct: 118 LIVPGLVFAASGERLGFGGGYYDRYLV------KTTGTKVALALPAQWVATPTWPVAEYD 171
Query: 187 QKVDEV 192
+DE+
Sbjct: 172 VLLDEI 177
>UniRef50_A2U6F2 Cluster: 5-formyltetrahydrofolate cyclo-ligase
precursor; n=1; Bacillus coagulans 36D1|Rep:
5-formyltetrahydrofolate cyclo-ligase precursor -
Bacillus coagulans 36D1
Length = 191
Score = 70.9 bits (166), Expect = 2e-11
Identities = 45/184 (24%), Positives = 89/184 (48%), Gaps = 8/184 (4%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 69
KA +R E+ ++ L EK+ + + + + + +K S + + +S E DT +I+
Sbjct: 3 KAEMRREMIGRLKRLDLNEKQAIEEKLQQILFSSDIWKISGTVGVTVSQHFEWDTRRIIE 62
Query: 70 HIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLI 129
A+G VP+ ++ + D + K+ + + ++ +E +DL+
Sbjct: 63 TGWAQGKTICVPKCVPKEKALVFYQLDDFTQLKKSFFNLLEPEPEETVK--IEKQAIDLL 120
Query: 130 IAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQKV 189
I PG+ F + G R+G GGGYYD+F+ P + V++ +CQ+ VP+ D V
Sbjct: 121 IVPGLVFDKKGFRIGFGGGYYDRFLAGF---PN---QTVSLIHSCQLKAHVPSESYDIPV 174
Query: 190 DEVI 193
+++
Sbjct: 175 RQIV 178
>UniRef50_Q9P7W2 Cluster: Putative 5-formyltetrahydrofolate
cyclo-ligase; n=1; Schizosaccharomyces pombe|Rep:
Putative 5-formyltetrahydrofolate cyclo-ligase -
Schizosaccharomyces pombe (Fission yeast)
Length = 204
Score = 70.9 bits (166), Expect = 2e-11
Identities = 53/195 (27%), Positives = 93/195 (47%), Gaps = 9/195 (4%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMST-ENEIDTAPLI 68
K LR + + + L + QS + ++V+ +K + LYM+ + E+ T LI
Sbjct: 5 KNQLRAILNSSLGKLADHIIDSQSISICKQVVELPEWKRCKNVCLYMNMPKKEVRTRCLI 64
Query: 69 KHIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDL 128
G F+P+ G + ++ +++ K GI++ + + ET +L
Sbjct: 65 DVAFKEGKNVFIPKCIGSHVMEMYQVFEKTESLTINKWGIAEPNGESRKIMDDETD-CEL 123
Query: 129 IIAPGVAFSRSGDRLGHGGGYYDKFITNLR---LNPETAPKI--VAVAFNCQVVD--EVP 181
II PGVAF RLGHG GYYD +I+ + L E+ + V + Q++ E+P
Sbjct: 124 IIVPGVAFDEKLSRLGHGKGYYDNYISKYQSWALQKESRANMFKVGICLKEQILPNREIP 183
Query: 182 TNEQDQKVDEVIFAE 196
+ +DQK+D ++ E
Sbjct: 184 MDTRDQKLDALVTPE 198
>UniRef50_A0V3Q2 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Clostridium cellulolyticum H10|Rep:
5-formyltetrahydrofolate cyclo-ligase - Clostridium
cellulolyticum H10
Length = 182
Score = 70.5 bits (165), Expect = 2e-11
Identities = 44/175 (25%), Positives = 93/175 (53%), Gaps = 7/175 (4%)
Query: 23 ALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQARGAAAFVPQ 82
+++++ + +SQI+ +K+ + K + + Y+S +E+ T +I ++ VP+
Sbjct: 11 SISSDNLQLKSQIIADKLNELDFVKRADTLMCYVSFGSEVYTHGIINAWFSQDKEVCVPR 70
Query: 83 YAGGRMRMLH-LETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLIIAPGVAFSRSGD 141
G+ R + ++ + + + G+ + +Q + + +D++I PG AF + +
Sbjct: 71 VLKGKGRAMEAVKISSLEELEQGTFGVLEPPLEQK--NIITPASIDVVIVPGCAFDLNRN 128
Query: 142 RLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQKVDEVIFAE 196
R+G+G GYYD+F L+L K V +AF+ Q++ ++P NE D +D +I E
Sbjct: 129 RMGYGAGYYDRF---LKLISHNCLK-VGIAFDFQIMGKIPCNELDIPMDILITEE 179
>UniRef50_Q21EV7 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Saccharophagus degradans 2-40|Rep:
5-formyltetrahydrofolate cyclo-ligase - Saccharophagus
degradans (strain 2-40 / ATCC 43961 / DSM 17024)
Length = 194
Score = 70.1 bits (164), Expect = 3e-11
Identities = 42/142 (29%), Positives = 74/142 (52%), Gaps = 4/142 (2%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 69
K LR + AK ALT ++ S+ V + S Y+ ++ IA Y++ + E+D P +K
Sbjct: 3 KDTLRQTMRAKRNALTPSQQAFASEQVATHLAQSSDYQQATHIAFYLACDGELDLTPALK 62
Query: 70 HIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLI 129
A A ++P A R ++ + ++ ++GI++ D + ++ LDL+
Sbjct: 63 QALADNKACYLPVIAPNR-QLRFRRYNEGCSLVTNRYGIAEPSAD---NPEIQPNRLDLV 118
Query: 130 IAPGVAFSRSGDRLGHGGGYYD 151
+AP V F + +RLG GGG+YD
Sbjct: 119 LAPLVGFDSNFNRLGMGGGFYD 140
>UniRef50_Q08SB2 Cluster: 5,10-methenyltetrahydrofolate synthetase;
n=2; Cystobacterineae|Rep: 5,10-methenyltetrahydrofolate
synthetase - Stigmatella aurantiaca DW4/3-1
Length = 245
Score = 70.1 bits (164), Expect = 3e-11
Identities = 50/185 (27%), Positives = 83/185 (44%), Gaps = 9/185 (4%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAP-LI 68
K LR+E+ A+ A+T + + V + + +Y+ + +ALY E+ T LI
Sbjct: 51 KQSLRDELTARRKAMTPDLIDGRGLKVQSRFLASPYYQKARTVALYAPIRGEVPTRDILI 110
Query: 69 KHIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDL 128
+Q + + GR+ + + P + G+ + D + +DL
Sbjct: 111 AALQDEKIVCYPLSHVHGRILSFRAIKSEAELEPG-RLGVREPTNSS---DLVPVDQIDL 166
Query: 129 IIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQK 188
+ PG+ F+R G RLG GGGYYD LR + V + FN QVV +P N D
Sbjct: 167 FVVPGLGFTRDGKRLGRGGGYYD---ATLRA-ASARSRRVGLGFNDQVVPWLPVNGDDVD 222
Query: 189 VDEVI 193
+D ++
Sbjct: 223 MDLIV 227
>UniRef50_A7DEJ5 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=2; Methylobacterium extorquens PA1|Rep:
5-formyltetrahydrofolate cyclo-ligase - Methylobacterium
extorquens PA1
Length = 262
Score = 70.1 bits (164), Expect = 3e-11
Identities = 52/184 (28%), Positives = 80/184 (43%), Gaps = 10/184 (5%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 69
KA LR E ++ AL+ E +K S E + + + + +EID PLI+
Sbjct: 78 KASLRAEALSRRDALSPEARKAGSLRAAETIAAIPELAEAPLVGAFWPIRSEIDPRPLIE 137
Query: 70 HIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLI 129
+ ARG +P+ + G+E G + RDD LI
Sbjct: 138 RLFARGQRVALPKVTKQGLVFREWRAGEELVS-------GGFGLSEPRDDLPPLDPTALI 190
Query: 130 IAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQKV 189
+ P AF R+G R+G+G GYYD+ I L N V +AF+ Q + VP D+ +
Sbjct: 191 V-PLAAFDRAGQRIGYGAGYYDQAIERLSKNGPVL--TVGIAFSVQEIAHVPAEPHDRPL 247
Query: 190 DEVI 193
D ++
Sbjct: 248 DHLV 251
>UniRef50_A7B2U8 Cluster: Putative uncharacterized protein; n=1;
Ruminococcus gnavus ATCC 29149|Rep: Putative
uncharacterized protein - Ruminococcus gnavus ATCC 29149
Length = 179
Score = 70.1 bits (164), Expect = 3e-11
Identities = 45/172 (26%), Positives = 87/172 (50%), Gaps = 10/172 (5%)
Query: 24 LTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQARGAAAFVPQY 83
LT+ E + S + E+V++H + + I Y+S E+ T ++ G VP+
Sbjct: 8 LTDREWETYSDRITEQVVSHPLFVQAKEIWCYVSMGKEVCTEQILVSAWRAGKRTAVPKV 67
Query: 84 AGGR-MRMLHLETGDEQTMPKTKHGISQHGKDQ-ARDDALETGGLDLIIAPGVAFSRSGD 141
G R M+ ++E+ ++ + GI + +++ D LE L L++ PGV+F +G
Sbjct: 68 TGKREMKFYYIESLND--LETGAFGILEPKEEKKGADCCLEKSDL-LMLVPGVSFDPAGR 124
Query: 142 RLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQKVDEVI 193
R+G+GGG+YD ++ + +AF Q+ D++P D +++ V+
Sbjct: 125 RIGYGGGFYDTYLQKME-----GCHTFGLAFEVQMADQIPAEAHDIRMEYVM 171
>UniRef50_A1S972 Cluster: 5-formyltetrahydrofolate cyclo-ligase
family protein; n=1; Shewanella amazonensis SB2B|Rep:
5-formyltetrahydrofolate cyclo-ligase family protein -
Shewanella amazonensis (strain ATCC BAA-1098 / SB2B)
Length = 228
Score = 70.1 bits (164), Expect = 3e-11
Identities = 50/195 (25%), Positives = 93/195 (47%), Gaps = 13/195 (6%)
Query: 2 SPIKPNPAKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENE 61
S I N +++ +R + A L+ + + + + ++ + R+ALY+ + E
Sbjct: 32 SGISANSSRSAIRKHVRALRRTLSGDVQTAAAIQAAQHLLTE--LADARRVALYLENDGE 89
Query: 62 IDTAPLIKHIQARGAAAFVP---QYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARD 118
I T PLI+ + +G ++P +A G + + + E M +GI + A
Sbjct: 90 ISTRPLIEALWQQGVEVYLPVLHPFAEGHLLFIRYDKHSE--MRDNLYGIPE--PVMACH 145
Query: 119 DALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVD 178
LD II P VAF SG+RLG GGG+YD+ + L P++ +++ +A +CQ +
Sbjct: 146 RLCPAYRLDAIITPLVAFDDSGNRLGMGGGFYDRTLAQL---PDST-RVIGLAHDCQRLP 201
Query: 179 EVPTNEQDQKVDEVI 193
+P D + ++
Sbjct: 202 ALPVEAWDVPLTTIV 216
>UniRef50_UPI0000DAE4A8 Cluster: hypothetical protein
Rgryl_01000426; n=1; Rickettsiella grylli|Rep:
hypothetical protein Rgryl_01000426 - Rickettsiella
grylli
Length = 195
Score = 69.7 bits (163), Expect = 4e-11
Identities = 44/185 (23%), Positives = 86/185 (46%), Gaps = 5/185 (2%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 69
+ L R ++ + A ++++++K S ++ EK+ H + S IA Y + NEID + LI
Sbjct: 4 RQLSRKKLQQQRAKISSDDQKIASALLVEKLSRHPLFFQSQTIASYHAIHNEIDPSALIH 63
Query: 70 HIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLI 129
+ ++P G ++ E + + K + I + +R + +DL+
Sbjct: 64 NAWQHKKKCYLPVVQGEQLIFCSFEI--DTLLKKNQFNIPE--PPLSRTTCIAAAAIDLV 119
Query: 130 IAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPE-TAPKIVAVAFNCQVVDEVPTNEQDQK 188
P + F+ G RLG G G+YDK + L P + P ++ +A+ Q + D
Sbjct: 120 FVPLLGFTEKGQRLGRGAGFYDKSFSFLLHPPRPSRPFLLGLAYEWQKLTNFTDKSWDVP 179
Query: 189 VDEVI 193
++ +I
Sbjct: 180 LNAII 184
>UniRef50_Q14L13 Cluster: Putative 5-formyltetrahydrofolate
cyclo-ligase protein; n=1; Spiroplasma citri|Rep:
Putative 5-formyltetrahydrofolate cyclo-ligase protein -
Spiroplasma citri
Length = 183
Score = 69.7 bits (163), Expect = 4e-11
Identities = 46/187 (24%), Positives = 92/187 (49%), Gaps = 10/187 (5%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 69
K +R E + +++E ++++ +++ H ++S IALY S +NE++T +IK
Sbjct: 6 KQEIRQEKLLARSKISSELRQQKETKIFDTFFQHPGVQNSKTIALYYSIKNEVNTLLIIK 65
Query: 70 HIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLI 129
+ A +P+ G ++ H+ + + + +A + +D++
Sbjct: 66 RLFALKVNILLPRMDGNNLKFYHITNLTTDLEFNLRFNLYEPLNSLPIINAEK---IDVL 122
Query: 130 IAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVV-DEVPTNEQDQK 188
+ P VAF ++ RLG+G GYYD+F+ N ++ +AF Q+V +P E D K
Sbjct: 123 VVPIVAFDQNNFRLGYGKGYYDRFLKNYH------HLVIGLAFIEQLVPTPLPVEEHDVK 176
Query: 189 VDEVIFA 195
++ +I A
Sbjct: 177 IEIIISA 183
>UniRef50_Q0A5K9 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Alkalilimnicola ehrlichei MLHE-1|Rep:
5-formyltetrahydrofolate cyclo-ligase - Alkalilimnicola
ehrlichei (strain MLHE-1)
Length = 209
Score = 69.7 bits (163), Expect = 4e-11
Identities = 45/170 (26%), Positives = 82/170 (48%), Gaps = 3/170 (1%)
Query: 13 LRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQ 72
+R+ + A+ A ++ ++ + +V H ++ R+A +M + E+D PL++ +
Sbjct: 15 VRHAMRARRRAQPMAVRRWAARQLARRVARHPLLRNVRRLAAFMPADGEMDPLPLMRRLH 74
Query: 73 ARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLIIAP 132
RG ++P G + + + + GI + + + L LDL++ P
Sbjct: 75 RRGITLYLPVVRPGSRVLRFRAWCPGRPLRPNRFGIPEPLPNSS--PLLRPRDLDLVLTP 132
Query: 133 GVAFSRSGDRLGHGGGYYDKFITNL-RLNPETAPKIVAVAFNCQVVDEVP 181
VAF G RLG GGG+YD L R T P+++ VA++ Q V E+P
Sbjct: 133 LVAFDHRGGRLGMGGGFYDASFAFLGRWRWRTHPRLLGVAWSFQHVPELP 182
>UniRef50_A4A119 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Blastopirellula marina DSM 3645|Rep:
5-formyltetrahydrofolate cyclo-ligase - Blastopirellula
marina DSM 3645
Length = 197
Score = 69.7 bits (163), Expect = 4e-11
Identities = 45/167 (26%), Positives = 82/167 (49%), Gaps = 7/167 (4%)
Query: 28 EKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQARGAAAFVPQYAGGR 87
++ +S + ++ N +S++ + Y++ E+DT L+ + A VP
Sbjct: 25 DRSERSVRIQARISNWLPQQSAATLLCYVNARCEVDTRSLLHQLLADERRVVVPYCLDDN 84
Query: 88 MRMLHLETGDEQTMPKTKHGISQHGKDQARDDA-LETGGLDLIIAPGVAFSRSGDRLGHG 146
L L + + + + GI + + Q RD + +DL I PGVAF G+RLG+G
Sbjct: 85 HLGLFLLSNMSE-LATGRFGILEP-RHQLRDSKRISPVEIDLAILPGVAFDLHGNRLGYG 142
Query: 147 GGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQKVDEVI 193
GY+D+ ++ +R T A+AF CQ+ ++PT D +D ++
Sbjct: 143 KGYFDRLLSEMRPQAVTC----ALAFECQLTAQIPTEPHDLPIDYLV 185
>UniRef50_A0NJT9 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=2; Oenococcus oeni|Rep: 5-formyltetrahydrofolate
cyclo-ligase - Oenococcus oeni ATCC BAA-1163
Length = 182
Score = 69.7 bits (163), Expect = 4e-11
Identities = 41/184 (22%), Positives = 93/184 (50%), Gaps = 12/184 (6%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 69
K LR + ++ + ++KK QS ++Y+ + + + +S IA+ +S E++T P++K
Sbjct: 7 KQKLRRQQKKRLDSYDPDDKKDQSILLYQALFESNDWLNSETIAVTLSLPLELNTKPIVK 66
Query: 70 HIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLI 129
VP+ +M + + + P H + + + +E L+
Sbjct: 67 QAWELDKRVLVPKIIDKKMIFVEFDE-TSKLAPGKFHTLEPETSVEIPKEEIE-----LM 120
Query: 130 IAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQKV 189
I PG+AF++SG RLG G G+YD+++ + + + V++ Q+++ +P ++ D ++
Sbjct: 121 IVPGLAFTKSGKRLGFGAGFYDRYLA------DYSGRTVSLVLKDQLLENIPNDKLDIRI 174
Query: 190 DEVI 193
+++
Sbjct: 175 KKIL 178
>UniRef50_Q4P9A6 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 254
Score = 69.7 bits (163), Expect = 4e-11
Identities = 66/226 (29%), Positives = 108/226 (47%), Gaps = 41/226 (18%)
Query: 9 AKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTE-NEIDTAPL 67
+K LR +A +A + +E QSQ V E+V+ Y + I++Y++ + E+ T +
Sbjct: 13 SKRQLRKSMAQTLANMRPDEIASQSQKVAEQVLKSQTYARARSISVYINMDVGEVKTDEI 72
Query: 68 IKHIQARG--------AAAFVPQYAGGR----------------MRMLHLETGDE-QTMP 102
+ + G A+ P A G M ML L + E ++M
Sbjct: 73 CRSVLKDGKKLYVPLFASPAAPVTASGPTVSSAPVQVKTEFATDMIMLRLRSVAEYESMA 132
Query: 103 KTKHGISQHG--------KDQARDDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFI 154
+ GI + ++QA D+ GLDLI+APGVAF ++G RLGHG GYYD+++
Sbjct: 133 VNRWGIREPPLTYADGTIREQALDETTGGDGLDLILAPGVAFDQTGGRLGHGKGYYDRYL 192
Query: 155 TNLR----LNPETAPKIVAVAFNCQVV---DEVPTNEQDQKVDEVI 193
T + P +A+A QV+ + VP +E+D+ +D +I
Sbjct: 193 TRAEEWASQCGASPPVTMALALREQVLPASERVPADERDRVLDGII 238
>UniRef50_O67621 Cluster: Putative uncharacterized protein; n=1;
Aquifex aeolicus|Rep: Putative uncharacterized protein -
Aquifex aeolicus
Length = 186
Score = 69.3 bits (162), Expect = 6e-11
Identities = 49/185 (26%), Positives = 87/185 (47%), Gaps = 15/185 (8%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 69
K+ LR ++ K L+ EE++R S+ V + + +K S ++ALY + E+D PL
Sbjct: 3 KSELRKKVLHKRINLSEEERRRLSEKVISNLKSLPEFKKSKKVALYCPIKGEVDLTPLFP 62
Query: 70 HIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHG-KDQARDDALETGGLDL 128
+ + +P+ G + + + + P G+ G + + + +D
Sbjct: 63 EV-LKEKELILPKVEGNEISLYRVHS------PACL-GVGAFGIMEPVEGERVNPEDVDF 114
Query: 129 IIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQK 188
I PGVAF G RLG G GYYD+ + ++ V VA++ QV + +P + D
Sbjct: 115 IAVPGVAFDLEGYRLGFGKGYYDRLLKRVK------GLKVGVAYSFQVFERLPRDAWDIP 168
Query: 189 VDEVI 193
VD ++
Sbjct: 169 VDVLV 173
>UniRef50_Q2BL70 Cluster: Putative uncharacterized protein; n=1;
Neptuniibacter caesariensis|Rep: Putative
uncharacterized protein - Neptuniibacter caesariensis
Length = 194
Score = 69.3 bits (162), Expect = 6e-11
Identities = 47/183 (25%), Positives = 84/183 (45%), Gaps = 4/183 (2%)
Query: 13 LRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQ 72
LR +I + +LT ++ +Q + + ++ + IA+Y+ + EID PLIK
Sbjct: 7 LRKQIRSLRRSLTPSQQNTAAQALLRNMRTRQDFRRAKSIAMYLPNDGEIDPTPLIKLCW 66
Query: 73 ARGAAAFVPQ-YAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLIIA 131
G ++P + R+ + + M + + I + + R A LDL++
Sbjct: 67 KLGKEVYLPVLHPILHNRLWFVPYTQKTPMVRNIYSIREPKLEPGRRKA--AWALDLVLL 124
Query: 132 PGVAFSRSGDRLGHGGGYYDKFITNLRLNP-ETAPKIVAVAFNCQVVDEVPTNEQDQKVD 190
P VAF G+R+G GGGYYD+ L P ++ +A Q V+E+P D +
Sbjct: 125 PLVAFDPKGNRMGMGGGYYDRTFAFKGLKKGMRGPDLIGLAHEIQRVEELPVEGWDIPLT 184
Query: 191 EVI 193
++
Sbjct: 185 TIV 187
>UniRef50_Q041X5 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=2; Lactobacillus|Rep: 5-formyltetrahydrofolate
cyclo-ligase - Lactobacillus gasseri (strain ATCC 33323
/ DSM 20243)
Length = 195
Score = 69.3 bits (162), Expect = 6e-11
Identities = 45/149 (30%), Positives = 76/149 (51%), Gaps = 9/149 (6%)
Query: 9 AKALLRNEIAAKIAALTNEEKK-RQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPL 67
+K LR K+ N ++K + +I+ EK++ S + I + +S E++TAP+
Sbjct: 15 SKKELRKLQIKKLTEFANSKQKLSEDKILKEKLLRSSLLTKAESIGISVSMPIEVNTAPI 74
Query: 68 IKHIQARGAAAFVPQYAGGRMRMLHLETGDEQT-MPKTKHGISQHGKDQARDDALETGGL 126
I + G ++P+ R + D+ T + KTK G+ ++ +A+ L
Sbjct: 75 IASLWKMGKRVYIPRCL--PKRKMEFTLYDKNTILVKTKFGVLENHD----SEAIVNNNL 128
Query: 127 DLIIAPGVAFSRS-GDRLGHGGGYYDKFI 154
DLII PG+A+ RLG GGGYYD+F+
Sbjct: 129 DLIIVPGLAYGLDRNSRLGFGGGYYDRFL 157
>UniRef50_Q1JZM9 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Desulfuromonas acetoxidans DSM 684|Rep:
5-formyltetrahydrofolate cyclo-ligase - Desulfuromonas
acetoxidans DSM 684
Length = 184
Score = 68.9 bits (161), Expect = 7e-11
Identities = 49/175 (28%), Positives = 85/175 (48%), Gaps = 12/175 (6%)
Query: 23 ALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKH-IQARGAAAFVP 81
+L +E +R S+ +++++ + + IALY +E++T L + + AR F P
Sbjct: 16 SLAVDEYRRLSRCAQQRLLSLPQFDQAQTIALYSPIRHEVETTLLFEAALDARKCVVF-P 74
Query: 82 QYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLIIAPGVAFSRSGD 141
Q GRM T D + G+ + Q + LDL++ PGVAF R G
Sbjct: 75 QVKDGRMSFAI--TPDTHSFCPGCFGVLEPTGCQQ----VAVNQLDLVVVPGVAFGRCGS 128
Query: 142 RLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQKVDEVIFAE 196
RLG+G G+YD+ + P + +V + F+ Q+ D++P D +D ++ E
Sbjct: 129 RLGYGKGFYDQ---TFEVRPSSC-LLVGLGFSFQLEDDLPKESHDIGLDYIVTDE 179
>UniRef50_A1HT82 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Thermosinus carboxydivorans Nor1|Rep:
5-formyltetrahydrofolate cyclo-ligase - Thermosinus
carboxydivorans Nor1
Length = 197
Score = 68.9 bits (161), Expect = 7e-11
Identities = 51/190 (26%), Positives = 83/190 (43%), Gaps = 7/190 (3%)
Query: 7 NPAKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAP 66
N KA LR + A+ L + QS+ ++ ++N Y+++ I LY++ +E T
Sbjct: 5 NNRKAALRQHMLAQRRRLAPQWVDEQSRKIHSHLLNWPLYRAARTIMLYLAMADEPQTDA 64
Query: 67 LIKHIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGL 126
+I VP M + + G+ D A ++ +
Sbjct: 65 IIIDALKTDKTVCVPVLGQQYGIMEAAVISGLDDLVTGRLGLRM--PDPACAKNIDPARI 122
Query: 127 DLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQD 186
DL+ PGVAF R G+RLG G GYYD+F+T V +A++ QV D VP D
Sbjct: 123 DLVFVPGVAFDREGNRLGMGAGYYDRFLTR-----ALQALFVGMAWSFQVADAVPAATHD 177
Query: 187 QKVDEVIFAE 196
++ ++ E
Sbjct: 178 ISMNYLLTEE 187
>UniRef50_Q0YQW9 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=2; Chlorobium/Pelodictyon group|Rep:
5-formyltetrahydrofolate cyclo-ligase - Chlorobium
ferrooxidans DSM 13031
Length = 207
Score = 68.5 bits (160), Expect = 1e-10
Identities = 51/189 (26%), Positives = 92/189 (48%), Gaps = 9/189 (4%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALY--MSTENEIDTAPL 67
K R +A + A++ E ++ S+ + V++ S+ IALY + E++T PL
Sbjct: 20 KEATRALMAERRGAISAERRRIMSETISAHVLSLPEVMSARLIALYIPLPAHPEVNTWPL 79
Query: 68 IKHIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLD 127
++ + VP + G+ + + G + D+A+ LD
Sbjct: 80 VEALTLLDKQLAVPVVQDQELCSALYRKGEP--LRGARFGQPEPEVLVKADEAM----LD 133
Query: 128 LIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQ 187
+++ P +AF RSG RLG+G G+YD+F+ L L P + +AF+ Q++D VP + D+
Sbjct: 134 VVLIPLLAFDRSGYRLGYGKGFYDRFLHRLSLE-GFRPLRIGLAFSMQMIDTVPHDSWDE 192
Query: 188 KVDEVIFAE 196
+D V+ E
Sbjct: 193 PLDGVVHEE 201
>UniRef50_Q049I2 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Lactobacillus delbrueckii subsp. bulgaricus ATCC
BAA-365|Rep: 5-formyltetrahydrofolate cyclo-ligase -
Lactobacillus delbrueckii subsp. bulgaricus (strain ATCC
BAA-365)
Length = 190
Score = 68.5 bits (160), Expect = 1e-10
Identities = 49/170 (28%), Positives = 86/170 (50%), Gaps = 13/170 (7%)
Query: 29 KKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQARGAAAFVPQ-YAGGR 87
KKRQ Q + + H + + +I L + E+D LIK ++ G ++ + + G +
Sbjct: 27 KKRQDQELTSLALQHPLVQEAKKIGLTLPMLLEVDINGLIKELRGEGKELYLAKCHPGWQ 86
Query: 88 MRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLIIAPGVAFSRSG-DRLGHG 146
+ L + G + +TK G+ + +++ D+A LDL+ PG+AFS +G R+G G
Sbjct: 87 LDFLKWDEG--APLMQTKFGVWELAEEKEADNA-----LDLLFVPGLAFSPAGKSRIGFG 139
Query: 147 GGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQKVDEVIFAE 196
GGYYD+F+ + A A+ F V P + DQ +D++I +
Sbjct: 140 GGYYDRFLAQNSVQ-TLALVNSAMYFKTPV---WPMEDHDQAMDDLIIVK 185
>UniRef50_Q31FB9 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Thiomicrospira crunogena XCL-2|Rep:
5-formyltetrahydrofolate cyclo-ligase - Thiomicrospira
crunogena (strain XCL-2)
Length = 192
Score = 68.1 bits (159), Expect = 1e-10
Identities = 49/185 (26%), Positives = 82/185 (44%), Gaps = 7/185 (3%)
Query: 13 LRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQ 72
LRN K L+ E++ ++ ++ +W + RIA+Y S + E+ T LI +
Sbjct: 3 LRNTCREKRNQLSPEQQFHHAKKASRLLLRSNWLQRPKRIAVYFSQDGELSTESLIDALW 62
Query: 73 ARGAAAFVPQYAGGRMR-MLHLETGDEQTMPKTKHGISQHGKDQARDDALETG-GLDLII 130
R F+P R R M E + + + GI + Q ++ TG LDL++
Sbjct: 63 QRNHQVFLPVLKTLRGRHMAFAEYTPQSVLASNRFGILE---PQVQNQHHLTGQQLDLVL 119
Query: 131 APGVAFSRSGDRLGHGGGYYDKFITNLR--LNPETAPKIVAVAFNCQVVDEVPTNEQDQK 188
P F G R G GGG+YD+ R + PK++ A CQ V+ + D
Sbjct: 120 MPLTCFDLEGHRTGMGGGFYDRTFQFKRWQTHRHNRPKLIGWAHECQQVEHIQPEPWDIP 179
Query: 189 VDEVI 193
++ ++
Sbjct: 180 LEGLV 184
>UniRef50_A5ZYS6 Cluster: Putative uncharacterized protein; n=3;
Bacteria|Rep: Putative uncharacterized protein -
Ruminococcus obeum ATCC 29174
Length = 249
Score = 68.1 bits (159), Expect = 1e-10
Identities = 58/187 (31%), Positives = 89/187 (47%), Gaps = 13/187 (6%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 69
K ++R ++ A A T+++ S+ + E V Y +S RI Y +E+ T +I+
Sbjct: 71 KKVIRKKVFAARKAHTDQQIDDWSRKIAETVTALPEYSNSRRILAYADYNHEVMTKYIIE 130
Query: 70 HIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLI 129
G VP+ G M+ + D + K GI + AR + ++ L+
Sbjct: 131 AAWNDGKEVAVPKVVG--QDMVFYKLTDFAQLEKGYFGIPE----PARGEIVQWEEA-LM 183
Query: 130 IAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQKV 189
I PGVAF R R+G+GGG+YD+F L +P VAVAF Q++ EVP D
Sbjct: 184 IMPGVAFDRQNHRVGYGGGFYDRF---LEKHPYITR--VAVAFEFQMMSEVPVEPTDIS- 237
Query: 190 DEVIFAE 196
E+I E
Sbjct: 238 PEIIVTE 244
>UniRef50_A4B9S4 Cluster: Putative carbon-nitrogen ligase; n=1;
Reinekea sp. MED297|Rep: Putative carbon-nitrogen ligase
- Reinekea sp. MED297
Length = 196
Score = 68.1 bits (159), Expect = 1e-10
Identities = 38/184 (20%), Positives = 84/184 (45%), Gaps = 5/184 (2%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 69
K LR ++ + +L+ + +++ V E+++N++ + +++A+Y++ + E+D +
Sbjct: 7 KQQLRRDLRQRRQSLSAQVQEQARYAVVEQLLNNALFPLPAKVAVYIAQDGELDLCAFVA 66
Query: 70 HIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLI 129
RG ++P + M + + + GI + + + LD +
Sbjct: 67 LCWERGIEVYLPVLHADKPEMWFAGYQPDSALTPNRFGI----PEPTSESVIAPTELDWV 122
Query: 130 IAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQKV 189
+ P V F G RLG GGG+YD+ + + P+ P ++ VA Q +P D +
Sbjct: 123 LMPLVGFDEQGGRLGMGGGFYDRTFEHAQTWPK-PPTLIGVAHESQKTQIIPRESWDISL 181
Query: 190 DEVI 193
++
Sbjct: 182 HAIV 185
>UniRef50_Q0ALV8 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Maricaulis maris MCS10|Rep:
5-formyltetrahydrofolate cyclo-ligase - Maricaulis maris
(strain MCS10)
Length = 199
Score = 67.7 bits (158), Expect = 2e-10
Identities = 43/151 (28%), Positives = 74/151 (49%), Gaps = 9/151 (5%)
Query: 44 SWYKSSSR-IALYMSTENEIDTAPLIKHIQARGAAAFVPQYAGGRMRMLHLETGDEQTMP 102
+W ++ +A Y ++E+D PL+K + G + +P G + ++ D +
Sbjct: 39 AWLPAAGEPVAGYWPLDSELDPRPLMKRLNDLGHSLCLPVVQGHGLPLVFRGWADGDALE 98
Query: 103 KTKHGISQHGKDQARDDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPE 162
G+ + D+ A G L++ P +A RSG+RLG G GYYD + LR +
Sbjct: 99 CRAMGVMEPRDDRP---AFRPG---LVLVPLLACDRSGNRLGFGKGYYDYTLAALRAAGQ 152
Query: 163 TAPKIVAVAFNCQVVDEVPTNEQDQKVDEVI 193
+ V +AF+CQV+ +P DQ +D V+
Sbjct: 153 V--RAVGLAFDCQVLATIPAERHDQALDGVV 181
>UniRef50_Q03G82 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Pediococcus pentosaceus ATCC 25745|Rep:
5-formyltetrahydrofolate cyclo-ligase - Pediococcus
pentosaceus (strain ATCC 25745 / 183-1w)
Length = 187
Score = 67.7 bits (158), Expect = 2e-10
Identities = 51/171 (29%), Positives = 85/171 (49%), Gaps = 12/171 (7%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 69
K + R ++ + K+ + ++ E + K++ ++A+ MS E+DTAP+I+
Sbjct: 3 KNIFRQTQIKRLNQIDITSKRAKEALILESFFDQHEVKNARKLAITMSHGFELDTAPIIQ 62
Query: 70 HIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLI 129
+ G +VP+ R + PK + + G + R +A LDLI
Sbjct: 63 RLIENGKCVYVPRTLPERQMEFVEYNLNTPMQPKFQGILEPVGGNVVRPEA-----LDLI 117
Query: 130 IAPGVAFSRS-GDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDE 179
I PG+A+ S G RLG GGGYYD++ L+ P A KIV +AF+ Q+ +
Sbjct: 118 IVPGLAYEVSNGYRLGFGGGYYDRY---LKKTP--ASKIV-LAFSEQIYSD 162
>UniRef50_A1U687 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=4; Gammaproteobacteria|Rep: 5-formyltetrahydrofolate
cyclo-ligase - Marinobacter aquaeolei (strain ATCC
700491 / DSM 11845 / VT8)(Marinobacter
hydrocarbonoclasticus (strain DSM 11845))
Length = 211
Score = 67.7 bits (158), Expect = 2e-10
Identities = 46/189 (24%), Positives = 92/189 (48%), Gaps = 9/189 (4%)
Query: 9 AKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLI 68
+++ LR + K +LT E++ + S+ + ++ + + I +Y++ + EID + I
Sbjct: 18 SRSELRRHLRHKRRSLTFEQQTQASENLALNLLKNPDLHRARHIGIYLANDGEIDPSLYI 77
Query: 69 KHIQARGAAAFVPQ----YAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETG 124
+ +G ++P Y G +++ D + + GI + ++R
Sbjct: 78 DLARKKGIHFYLPILHPIYPG---KLVFSPYFDGVQLTANRFGIPEPPFPRSRRKP--AW 132
Query: 125 GLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNE 184
LD ++ P V F +G RLG GGG+YD+ R+ P APK++ +A + Q V+++P
Sbjct: 133 ALDAVLFPLVGFDETGGRLGMGGGFYDRTFAFSRIRPGMAPKLIGLAHDFQRVEQLPVEP 192
Query: 185 QDQKVDEVI 193
D + V+
Sbjct: 193 WDVPLHGVV 201
>UniRef50_Q3A217 Cluster: Putative ligase; n=1; Pelobacter
carbinolicus DSM 2380|Rep: Putative ligase - Pelobacter
carbinolicus (strain DSM 2380 / Gra Bd 1)
Length = 195
Score = 67.3 bits (157), Expect = 2e-10
Identities = 50/187 (26%), Positives = 85/187 (45%), Gaps = 10/187 (5%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 69
K LR + A+ L E S V ++V+ ++ + +ALY NE+ T +
Sbjct: 3 KKSLREIMLARRKHLAAEVCLGHSLRVQQRVLALPAFEQAKAVALYSPIFNEVFTEEIFH 62
Query: 70 HIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLI 129
RG P+ G ++ + L +Q P + G + + LDL+
Sbjct: 63 EALHRGKTVAYPRVRGDQLDFV-LVASPQQLSPGAFGVLEPTGSA-----TIPSSALDLV 116
Query: 130 IAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQKV 189
+ PGVAF G+RLG+G G+YD+ + P + V ++F Q+V+ +P + DQ +
Sbjct: 117 LVPGVAFDLEGNRLGYGKGFYDRVLCGSG-RPALS---VGLSFESQLVERLPVEDHDQCL 172
Query: 190 DEVIFAE 196
D +I E
Sbjct: 173 DLLITEE 179
>UniRef50_Q1FEZ7 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Clostridium phytofermentans ISDg|Rep:
5-formyltetrahydrofolate cyclo-ligase - Clostridium
phytofermentans ISDg
Length = 190
Score = 67.3 bits (157), Expect = 2e-10
Identities = 45/185 (24%), Positives = 90/185 (48%), Gaps = 8/185 (4%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 69
K LR + + ++ EE K +S + ++++ + + + ++S E+DT LI
Sbjct: 4 KYTLREKNRTQRNQMSEEESKVKSSTILDQLLRLPDFMMADDLFTFVSFGKEVDTHGLIT 63
Query: 70 HIQARGAAAFVPQYAGGR-MRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDL 128
G +VP+ + M +ET +E +P T + K+ + ++ +
Sbjct: 64 GALLSGKRVYVPKVLDKKFMEFYQIETLEE-LLPGTLGILEPEPKNMGQ---MKEDRNQI 119
Query: 129 IIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQK 188
+I PG+AF G+R+G+GGGYYD++ +P K VA+A++ Q+ + T + D
Sbjct: 120 MIVPGLAFDLMGNRIGYGGGYYDRYFIE---HPNPNLKKVAIAYDFQIEKVLQTEQFDVP 176
Query: 189 VDEVI 193
+ ++
Sbjct: 177 MHRIV 181
>UniRef50_A7HUZ2 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Parvibaculum lavamentivorans DS-1|Rep:
5-formyltetrahydrofolate cyclo-ligase - Parvibaculum
lavamentivorans DS-1
Length = 199
Score = 67.3 bits (157), Expect = 2e-10
Identities = 45/160 (28%), Positives = 75/160 (46%), Gaps = 9/160 (5%)
Query: 35 IVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQARGAAAFVPQYAG-GRMRMLHL 93
++ + H + S IA Y++ E D A LI+ + A+G +P+ A + H
Sbjct: 31 LIARHFLRHVPLSTGSCIAGYVAMMGEADPAELIERLSAQGHVCALPRVAAMNEPLVFHR 90
Query: 94 ETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKF 153
+P HG + + DA D+++ P +AF G RLG+GGGYYD+
Sbjct: 91 WRAGNVLLP------GAHGTREPQPDA-PVCRPDIVLVPLLAFDSVGRRLGYGGGYYDRT 143
Query: 154 ITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQKVDEVI 193
+ LR V VAF+ Q ++P + D+++D V+
Sbjct: 144 LAALR-EDRAGVLAVGVAFSAQEAQDLPEEQFDERLDWVV 182
>UniRef50_A4XKH5 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Caldicellulosiruptor saccharolyticus DSM 8903|Rep:
5-formyltetrahydrofolate cyclo-ligase -
Caldicellulosiruptor saccharolyticus (strain ATCC 43494
/ DSM 8903)
Length = 199
Score = 67.3 bits (157), Expect = 2e-10
Identities = 46/184 (25%), Positives = 92/184 (50%), Gaps = 9/184 (4%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 69
K +R I + ++N +K +VY + + + + +YMS E+DT+ +I
Sbjct: 3 KKKIRKIIGIRRRLISNFQKLHLDILVYLNLKKFLSKLNFNTVFVYMSLPYEVDTSRIIN 62
Query: 70 HIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLI 129
++ +G VP+ ++RM+ E + + + + GI + K+ + +D+
Sbjct: 63 YLSVKGKRICVPKIVD-KIRMIAGEYRKDGKLKRNRFGILEP-KETIE---VNPSDIDVC 117
Query: 130 IAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQKV 189
I P +AF ++ +R+G G GYYD+F+ + P V VA++ Q V ++P+ D K+
Sbjct: 118 IIPLLAFDQNLNRIGFGKGYYDRFLK--EVGPSCLK--VGVAYHFQKVPKIPSERHDVKL 173
Query: 190 DEVI 193
D ++
Sbjct: 174 DVIV 177
>UniRef50_A3CVT9 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Methanoculleus marisnigri JR1|Rep:
5-formyltetrahydrofolate cyclo-ligase - Methanoculleus
marisnigri (strain ATCC 35101 / DSM 1498 / JR1)
Length = 203
Score = 67.3 bits (157), Expect = 2e-10
Identities = 46/184 (25%), Positives = 81/184 (44%), Gaps = 10/184 (5%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 69
KA LR A L+ E+ S + EK++ + + +Y + E +T LI
Sbjct: 17 KAALRLRAKEARALLSPEDVAAYSASIEEKLLG--LLDGFTTVMVYAAKAPEAETKNLIA 74
Query: 70 HIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLI 129
+ RG VP + D + + + + + G ++ +
Sbjct: 75 ALNRRGVRVVVPIIERDTCSLRLSYLPDPSVLVPSTFDVPE---PIGHELPARPGDVEAV 131
Query: 130 IAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQKV 189
+ P +AF G+RLG+G GYYD+F L+ PK + +AF+CQ + +P +E D K+
Sbjct: 132 VIPMLAFDAEGNRLGYGAGYYDRF-----LHRYPHPKKIGIAFSCQQAERIPADENDVKM 186
Query: 190 DEVI 193
D ++
Sbjct: 187 DYIV 190
>UniRef50_A4E9T0 Cluster: Putative uncharacterized protein; n=1;
Collinsella aerofaciens ATCC 25986|Rep: Putative
uncharacterized protein - Collinsella aerofaciens ATCC
25986
Length = 198
Score = 66.5 bits (155), Expect = 4e-10
Identities = 56/200 (28%), Positives = 91/200 (45%), Gaps = 18/200 (9%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVI---NHSWYKSSSRIALYMSTENEIDTAP 66
KA LR + A+ AL + + +S I+ +++ + S + +A+Y + +E D A
Sbjct: 3 KAELRRAVIAQRDALDLDVRTAKSTIICARLVELLDRSDSAAPRTVAVYAAMGSEADPAA 62
Query: 67 LIKHIQARGAAAFVP--------QYAGGRMRMLHLETGDEQTMPKTKH---GISQHGKDQ 115
RG P G RM M + D P H + D
Sbjct: 63 FAAAAAVRGWRVAYPCMLSAIDAAACGQRMCMRAVAADDASAAPFIAHPTRAFAATDIDS 122
Query: 116 ARDDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQ 175
+ LD+I+ P VAF ++G RLG+GGG YD+++ L+P A +I+ +AF+ Q
Sbjct: 123 NHFPIVPAEALDMIVVPLVAFDQTGARLGYGGGCYDRYLP--MLSP--ACQIIGIAFDEQ 178
Query: 176 VVDEVPTNEQDQKVDEVIFA 195
VD VPT+ D + ++ A
Sbjct: 179 RVDRVPTDAHDLPLPHIVSA 198
>UniRef50_A3MYI1 Cluster: Putative uncharacterized protein; n=1;
Actinobacillus pleuropneumoniae L20|Rep: Putative
uncharacterized protein - Actinobacillus
pleuropneumoniae serotype 5b (strain L20)
Length = 191
Score = 66.1 bits (154), Expect = 5e-10
Identities = 51/185 (27%), Positives = 89/185 (48%), Gaps = 8/185 (4%)
Query: 13 LRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQ 72
LR I + A L E++ S + + + + IALY+ +EI PLI+ +Q
Sbjct: 12 LRQSILNERAKLALEQQSIASFNLIPQALALINQYHTEHIALYLPFNSEISPLPLIERLQ 71
Query: 73 ARGAAAFVPQYAGGRMRMLHLETGDEQTMPKT-KHGISQHGKDQARDDALETGGLDLIIA 131
+ + ++P L + D +T+ T K G+ Q D + L +++I
Sbjct: 72 QQNKSLYLPILHPFAKGHLFFQQYDAETLFITHKFGMQQPKPDVRKVKPLNE--IEMIFT 129
Query: 132 PGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQKVDE 191
P +A +SG+RLG+GGG+YD+ L L P+ V +A+ Q V+ +PT D ++
Sbjct: 130 PLLACDKSGNRLGYGGGFYDR---TLALTPQAIS--VGLAYPFQFVENLPTEPWDIPLNH 184
Query: 192 VIFAE 196
+I +
Sbjct: 185 LIIGD 189
>UniRef50_P40099 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=2; Saccharomyces cerevisiae|Rep:
5-formyltetrahydrofolate cyclo-ligase - Saccharomyces
cerevisiae (Baker's yeast)
Length = 211
Score = 66.1 bits (154), Expect = 5e-10
Identities = 55/198 (27%), Positives = 91/198 (45%), Gaps = 14/198 (7%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTEN-EIDTAPLI 68
K LLR +I I AL + +S + + V + +S R+A YMS + E+ T +I
Sbjct: 4 KQLLRRQIKRVINALDYDIIAAESHTISQAVRSLIASANSRRVACYMSMDKGEVTTGEII 63
Query: 69 KHIQARGAAAFVPQYAGG------RMRMLHLETGDEQTMPKTK--HGISQHGKDQARDDA 120
K++ G F+P+ ++R H M K + G Q ++
Sbjct: 64 KNLFQDGQEVFLPRCTHTSESKHFKLREDHHPHLIFHRMSSLKMVRDLKPQGPYQLKEPE 123
Query: 121 L---ETGGLDLIIAPGVAFS-RSGDRLGHGGGYYDKFITNLR-LNPETAPKIVAVAFNCQ 175
E+ LD+++ PGVAF ++G R+GHG GYYD F + L+ P +V + Q
Sbjct: 124 PHIEESDILDVVLVPGVAFDIKTGARMGHGAGYYDDFFQRYKILHEGQKPLLVGLCLMEQ 183
Query: 176 VVDEVPTNEQDQKVDEVI 193
V +P + D +D ++
Sbjct: 184 VASPIPLEKHDYSMDCIV 201
>UniRef50_Q0YHK3 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=3; Geobacter|Rep: 5-formyltetrahydrofolate
cyclo-ligase - Geobacter sp. FRC-32
Length = 201
Score = 65.7 bits (153), Expect = 7e-10
Identities = 50/187 (26%), Positives = 87/187 (46%), Gaps = 10/187 (5%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 69
K LR + +K AL+ E + S + + + S + + +ALY +E+DT L +
Sbjct: 19 KHSLRRLMLSKRRALSPLEVEAHSLRIQQSFMGSSEFLRAESLALYAPIHHEVDTVALQR 78
Query: 70 HIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLI 129
G P G ++ + + + GI + G+ ET +D+
Sbjct: 79 RSFFLGKKVLYPVVDGNKLTFRQIHAASD--LENGAFGIEEPGEKNIIH-LPET--IDIF 133
Query: 130 IAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQKV 189
+ PGVAF +G R+G+G G+YD+ + L E K V + ++ Q+VDE+ D +
Sbjct: 134 VIPGVAFDINGRRIGYGKGFYDRTLHLL----EGCGKFVGLCYDFQLVDEIVGEPHDVTM 189
Query: 190 DEVIFAE 196
D +IF+E
Sbjct: 190 D-LIFSE 195
>UniRef50_A4BS87 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Nitrococcus mobilis Nb-231|Rep:
5-formyltetrahydrofolate cyclo-ligase - Nitrococcus
mobilis Nb-231
Length = 210
Score = 65.7 bits (153), Expect = 7e-10
Identities = 48/181 (26%), Positives = 81/181 (44%), Gaps = 5/181 (2%)
Query: 9 AKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLI 68
+KA LR+ + + L E+ R ++ + + WY S RIA Y + + E+D +
Sbjct: 3 SKAELRHRMRRQRRQLGLCERTRAARQLTAVLRRSRWYHHSHRIACYWAMDGEMDLGAFL 62
Query: 69 KHIQARGAAAFVPQYAGGRMRMLHL-ETGDEQTMPKTKHGISQHGKDQARDDALETGGLD 127
+ G ++P + L + + + + GI + QA A LD
Sbjct: 63 QRAHQDGRVIYLPVLQKKPTKSLRFYQYRPGERLRANRFGIPEPRPRQANRIACRD--LD 120
Query: 128 LIIAPGVAFSRSGDRLGHGGGYYDKFITNLR--LNPETAPKIVAVAFNCQVVDEVPTNEQ 185
L++ P VAF + G RLG G G+YD LR P+++ +AF+ Q + E+P
Sbjct: 121 LVLVPLVAFDQQGHRLGMGAGFYDHTFAFLRHQRGRWRRPRLLGIAFSFQRIVELPVEPW 180
Query: 186 D 186
D
Sbjct: 181 D 181
>UniRef50_A4ABX0 Cluster: 5-formyltetrahydrofolate cyclo-ligase
family protein; n=1; Congregibacter litoralis KT71|Rep:
5-formyltetrahydrofolate cyclo-ligase family protein -
Congregibacter litoralis KT71
Length = 217
Score = 65.7 bits (153), Expect = 7e-10
Identities = 50/194 (25%), Positives = 91/194 (46%), Gaps = 13/194 (6%)
Query: 2 SPIKPNPAKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENE 61
S P ++ R+ + + A+ + + V + N S++ S+ IALY++ + E
Sbjct: 26 SAANPTLSRQACRSHLRQQRRAIAPSYAREAGERVAHYLRNSSFW-SADHIALYLANDGE 84
Query: 62 IDTAPLIKHIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDAL 121
+D A + + ++ G ++P M T DE P ++ G + +
Sbjct: 85 LDPAVIARAARSSGKHLYLPVITAEAMAFCEWRT-DEPLRP------NRFGIGEPTGTPV 137
Query: 122 ETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVP 181
L L+I P V ++ G RLG GGGYYD+F + ++ K VA+A++CQ D +
Sbjct: 138 PPRDLQLVILPTVGWTARGFRLGMGGGYYDRFFGS---KQASSAKRVALAYDCQRDDALE 194
Query: 182 TNEQ--DQKVDEVI 193
++ DQ +D V+
Sbjct: 195 QLKEAWDQPLDAVL 208
>UniRef50_Q1DNE6 Cluster: Putative uncharacterized protein; n=2;
Pezizomycotina|Rep: Putative uncharacterized protein -
Coccidioides immitis
Length = 233
Score = 65.7 bits (153), Expect = 7e-10
Identities = 62/220 (28%), Positives = 102/220 (46%), Gaps = 38/220 (17%)
Query: 9 AKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTEN-EIDTAPL 67
AK LR+ I ++ L+ E + + +++ Y+++ R+++Y++ + E+ TA +
Sbjct: 7 AKKELRSRIKTVLSGLSGESP---ASTITNALLSLPEYQAAKRLSVYLAMPSGEVQTADI 63
Query: 68 IKHIQARGAAAFVPQY-------AGGR---MRMLHLET-GDEQTMPKTKHGISQ------ 110
++ ++G +VP GR M ML L + D +++ K GI
Sbjct: 64 VRDAFSQGKQVYVPYIYQLDPVSTQGRKSVMEMLALRSIEDYESLQPDKWGIPSLDAGSL 123
Query: 111 ---------HGKDQARDDALETG--GLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLR- 158
+G + ET GLDLI+ PG+AF S RLGHG GYYD F R
Sbjct: 124 ATRENCFGGYGLRGLSHPSTETSKAGLDLIVVPGLAFDESFGRLGHGKGYYDHFFMRCRD 183
Query: 159 --LNPETAPKIVAVAFNCQVV---DEVPTNEQDQKVDEVI 193
+ P + A+A Q++ + VP EQD VD +I
Sbjct: 184 DTTSTSRKPYLAALALQEQILPPPERVPAGEQDYPVDALI 223
>UniRef50_Q88WQ3 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Lactobacillus plantarum|Rep:
5-formyltetrahydrofolate cyclo-ligase - Lactobacillus
plantarum
Length = 188
Score = 65.3 bits (152), Expect = 9e-10
Identities = 44/189 (23%), Positives = 95/189 (50%), Gaps = 14/189 (7%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 69
K R + +++ +T +++RQ+Q + ++ ++++ IA+ +S++ E+ T PLI+
Sbjct: 3 KKAFRKQQLGRLSQMTPADRQRQNQALQTQLFASPTWQTAQVIAMTISSDIEVATRPLIE 62
Query: 70 HIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLI 129
A G +P+ R + ++ + +T GI + + + +DLI
Sbjct: 63 QAWAEGKMVVIPKTLPHRQMAFYPYQATDR-LERTSFGI----PEPVTGEPVAKQQIDLI 117
Query: 130 IAPGVAFSRSGD-RLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVD--EVPTNEQD 186
+ PG+ +SR R+G GGGYYD+++ + K + +A++ + E P ++ D
Sbjct: 118 LVPGLGYSRDRHARIGFGGGYYDRYLA------DYPGKKLTLAYDEMAFEHAEWPVDQYD 171
Query: 187 QKVDEVIFA 195
+DE++ A
Sbjct: 172 VLLDELLVA 180
>UniRef50_Q44SK2 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Chlorobium limicola DSM 245|Rep:
5-formyltetrahydrofolate cyclo-ligase - Chlorobium
limicola DSM 245
Length = 195
Score = 65.3 bits (152), Expect = 9e-10
Identities = 46/187 (24%), Positives = 87/187 (46%), Gaps = 9/187 (4%)
Query: 9 AKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTEN--EIDTAP 66
+K LLR E+ + + E +S ++ +V+N + I +Y+S + E+ T
Sbjct: 7 SKQLLRKELLVRRKMMPEREWFEKSALIASEVLNIREVVEAEHILVYLSIDETREVYTGE 66
Query: 67 LIKHIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGL 126
L+ + G VP R+ + E G K + GI + ++ ++ L
Sbjct: 67 LVSGLLEAGKRLSVPVVDQRRLLAVRYEPGQ-----KLRRGIFGQSEPESIRP-VDASLL 120
Query: 127 DLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQD 186
+++ P VA G R+G+G G+YD+F+ L + + P +AF Q+V E+P + D
Sbjct: 121 QVVLLPLVAVDERGCRMGYGMGFYDRFLAEL-ASHKCFPCRAGLAFRLQIVPELPCDSWD 179
Query: 187 QKVDEVI 193
+ +D +
Sbjct: 180 EPLDYAV 186
>UniRef50_A6VUD0 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=2; Marinomonas|Rep: 5-formyltetrahydrofolate
cyclo-ligase - Marinomonas sp. MWYL1
Length = 194
Score = 65.3 bits (152), Expect = 9e-10
Identities = 43/184 (23%), Positives = 85/184 (46%), Gaps = 11/184 (5%)
Query: 13 LRNEIAAKIAALTNEEKKRQSQIV---YEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 69
LR ++ L++EE+ + + + Y +++ + R+ALY+S + EI L +
Sbjct: 11 LRRQLRQSRRNLSSEEQLKAADSLIHSYNEILEQLTIQPPKRVALYLSNDGEISPHLLCE 70
Query: 70 HIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLI 129
+ + ++P G ++ + + + GI K+ + + LD++
Sbjct: 71 YFWQQQIETYLPVVQGKQLTFACYSSAT--IWQENQFGI----KEPLTSEYVAGNELDIV 124
Query: 130 IAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQKV 189
+ P V F G RLG GGG+YD+ N R + + P ++ +A +CQ V +P D +
Sbjct: 125 LLPLVGFDSKGGRLGMGGGFYDRTFENKRADQK--PLLIGLAHDCQEVKSLPVEGWDVPL 182
Query: 190 DEVI 193
+I
Sbjct: 183 QAII 186
>UniRef50_Q6FTS7 Cluster: Similar to sp|P40099 Saccharomyces
cerevisiae YER183c FAU1; n=2; Saccharomycetales|Rep:
Similar to sp|P40099 Saccharomyces cerevisiae YER183c
FAU1 - Candida glabrata (Yeast) (Torulopsis glabrata)
Length = 229
Score = 65.3 bits (152), Expect = 9e-10
Identities = 51/213 (23%), Positives = 97/213 (45%), Gaps = 29/213 (13%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTEN-EIDTAPLI 68
K LR + + ++ EE QS+ + + ++ + +A YMS + E+DT +I
Sbjct: 8 KQQLRKHMGQTLGKISREEIISQSECIRDNLM--PILEGKQNVACYMSMDTGELDTGNII 65
Query: 69 KHIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPK--------TKHGISQH--------- 111
+ + G ++P+ ++ H++ ++ P T H + H
Sbjct: 66 ESLFEAGKKVYLPRCTHTKLTG-HVQLRNDSKNPGNMKDHPHLTFHEMDSHDHVLSLSPK 124
Query: 112 GKDQARDDALETGGL-------DLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRL-NPET 163
GK ++ +E L D I+ PGVAF+ RLGHG GYYD F + +L +
Sbjct: 125 GKYNLKEPDIEDEKLSPLPPMLDAILVPGVAFTSGCSRLGHGAGYYDDFFSRYKLQHSNQ 184
Query: 164 APKIVAVAFNCQVVDEVPTNEQDQKVDEVIFAE 196
P ++ +A Q+V+++P + D +D ++ +
Sbjct: 185 LPLLIGIALKQQIVEDIPMDAHDYFLDCILVGD 217
>UniRef50_A7DNA8 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Candidatus Nitrosopumilus maritimus SCM1|Rep:
5-formyltetrahydrofolate cyclo-ligase - Candidatus
Nitrosopumilus maritimus SCM1
Length = 187
Score = 65.3 bits (152), Expect = 9e-10
Identities = 44/187 (23%), Positives = 88/187 (47%), Gaps = 13/187 (6%)
Query: 7 NPAKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAP 66
N K LRN + K + + K S+ + +K+ ++ + +I Y +E+ T
Sbjct: 4 NSEKKSLRNLLLEKRDGTSFDLMKIASEKISKKLKKIKTFRDAQKIGAYYPIGSEVPTQD 63
Query: 67 LIKHIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGL 126
+I+ + + G F+P+ +G M + D ++ I + + D L
Sbjct: 64 IIQELLSDGKEVFLPRVSGENMDFKKIS--DFSSLESGSFEIME-----PKIDCETENNL 116
Query: 127 DLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQD 186
D+I+ P V + G RLG+G G+YD+F++N +++ +++ QVV +P ++ D
Sbjct: 117 DVILVPTVGITPKGIRLGYGHGFYDRFLSNHKIS------TISLTLEKQVVKNIPKSDHD 170
Query: 187 QKVDEVI 193
+D V+
Sbjct: 171 ILIDWVV 177
>UniRef50_Q38VZ7 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Lactobacillus sakei subsp. sakei 23K|Rep:
5-formyltetrahydrofolate cyclo-ligase - Lactobacillus
sakei subsp. sakei (strain 23K)
Length = 180
Score = 64.9 bits (151), Expect = 1e-09
Identities = 43/153 (28%), Positives = 80/153 (52%), Gaps = 9/153 (5%)
Query: 10 KALLRNEIAAKIAALTNE--EKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPL 67
K +R + A + L + K++Q I+ +K+I+ + ++S++ I + ++ E+ T P+
Sbjct: 4 KQQVRQQGLAALQRLAQQPANKQQQEAILLQKLIDSAAFQSATVIGMTLNQPIEVATQPI 63
Query: 68 IKHIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLD 127
I+ QA G VP+ R +M E + ++ G+ + Q + + D
Sbjct: 64 IEATQAAGKRIVVPRTLPKR-QMAFYELTPTTVLERSHFGVLE---PQITGEPIVP---D 116
Query: 128 LIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLN 160
L+I PGV FS G R+G GGGYYD+++ ++N
Sbjct: 117 LMIVPGVVFSLDGWRVGFGGGYYDRYLAAHQMN 149
>UniRef50_A7IJU7 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Xanthobacter autotrophicus Py2|Rep:
5-formyltetrahydrofolate cyclo-ligase - Xanthobacter sp.
(strain Py2)
Length = 195
Score = 64.9 bits (151), Expect = 1e-09
Identities = 44/144 (30%), Positives = 70/144 (48%), Gaps = 11/144 (7%)
Query: 52 IALYMSTENEIDTAPLIKHIQARGAAAFVPQYAGGRMRMLHLETGDEQT--MPKTKHGIS 109
+AL+ +EIDTAPL ++ GA +P R + L D+ T +P I
Sbjct: 49 VALFAPFRDEIDTAPLADALREAGAILALPVIIA-RDQPLLFRRWDQDTPLVPTGAFRIP 107
Query: 110 QHGKDQARDDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVA 169
+ G + +L++ P AF R G R+G+G G+YD+ + LR + + +
Sbjct: 108 EPGPEAPEIIP------ELLLVPLAAFDRRGFRIGYGAGFYDRTLALLR--AQRPVRAIG 159
Query: 170 VAFNCQVVDEVPTNEQDQKVDEVI 193
AF CQ VD+VP D+ VD ++
Sbjct: 160 FAFACQEVDQVPVETHDEPVDMMV 183
>UniRef50_A5P2B9 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=2; Methylobacterium sp. 4-46|Rep:
5-formyltetrahydrofolate cyclo-ligase - Methylobacterium
sp. 4-46
Length = 260
Score = 64.9 bits (151), Expect = 1e-09
Identities = 48/184 (26%), Positives = 84/184 (45%), Gaps = 10/184 (5%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 69
KA LR E A+ L + S+ + E V+ + ++ Y +E+D PLI
Sbjct: 69 KASLRREALARRDGLDAAYRAEASRRIAEAVLALPALAGAGLVSAYWPIRSEVDVRPLIA 128
Query: 70 HIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLI 129
++ RG A +PQ ++ + ++ + G+S+ G +A E L+
Sbjct: 129 ALRDRGQAVALPQVTPA--GLVFRQVAEDDALSAGGFGLSEPG-----PEAAEVRPRALL 181
Query: 130 IAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQKV 189
+ P AF R R+G+G GYYD+ + + L+ + V VAF Q + +VP D +
Sbjct: 182 V-PLAAFDRRLHRIGYGKGYYDRALAD--LSRDGPILTVGVAFAVQEIAQVPEGPHDHSL 238
Query: 190 DEVI 193
D ++
Sbjct: 239 DHIV 242
>UniRef50_A4B8C7 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=17; Gammaproteobacteria|Rep: 5-formyltetrahydrofolate
cyclo-ligase - Alteromonas macleodii 'Deep ecotype'
Length = 229
Score = 64.9 bits (151), Expect = 1e-09
Identities = 50/195 (25%), Positives = 96/195 (49%), Gaps = 12/195 (6%)
Query: 9 AKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLI 68
A+ +LR ++ AL+ ++++ +Q V +++ + ++ ++ IA Y+ + E+D I
Sbjct: 25 ARTILRKQLREARRALSPQQQRDAAQGVVKQLCSLNFLIEANTIAGYLVNDGEVDLKDYI 84
Query: 69 K-HIQARGAAAF-VPQ-YAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGG 125
+ QA A F +P + + +L L + K K+ I + + T
Sbjct: 85 EMQWQAPQAKQFALPVLHPICKGHLLFLSYTQHTALVKNKYNIEEPAL--VCPSVIPTSQ 142
Query: 126 LDLIIAPGVAFSRSGDRLGHGGGYYDKFI--TNLRLNPE-----TAPKIVAVAFNCQVVD 178
D+I+ P V F +G+RLG GGGYYD+ + T + P+ PK+V +A + Q V+
Sbjct: 143 CDVILMPLVGFDTNGNRLGMGGGYYDRTLAFTQRNVYPQKNISSNKPKLVGIAHDMQEVE 202
Query: 179 EVPTNEQDQKVDEVI 193
+P D +D ++
Sbjct: 203 ALPVASWDVPLDAIV 217
>UniRef50_A0Y9S2 Cluster: 5-formyltetrahydrofolate cyclo-ligase
family protein; n=1; marine gamma proteobacterium
HTCC2143|Rep: 5-formyltetrahydrofolate cyclo-ligase
family protein - marine gamma proteobacterium HTCC2143
Length = 197
Score = 64.9 bits (151), Expect = 1e-09
Identities = 44/187 (23%), Positives = 84/187 (44%), Gaps = 7/187 (3%)
Query: 9 AKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLI 68
++A LR + + L+ ++ + + +++ +K + IA Y + EID + +
Sbjct: 6 SRAKLRRTLRNRRRNLSAGQQLHAAGQISQRINQQRMFKRNKAIAFYWPNDGEIDPSIAL 65
Query: 69 KHIQARGAAAFVPQYA-GGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLD 127
K +G ++P G R+ G + + + GI + +A L
Sbjct: 66 KKASEKGYHCYLPVLMPGNRLWFARYLPGAQ--LKNNRFGIPE---PRAPRQYRRAWSLG 120
Query: 128 LIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPE-TAPKIVAVAFNCQVVDEVPTNEQD 186
L+ P V F R G RLG GGG+YD+ N R P + P+++ +A +CQ V + + D
Sbjct: 121 LVFLPLVGFDRQGGRLGMGGGFYDRTFANTRSAPAMSKPQLIGLAHHCQEVPSLQLAQWD 180
Query: 187 QKVDEVI 193
+ ++
Sbjct: 181 IPLTAIV 187
>UniRef50_Q8G439 Cluster: Putative uncharacterized protein; n=1;
Bifidobacterium longum|Rep: Putative uncharacterized
protein - Bifidobacterium longum
Length = 249
Score = 64.5 bits (150), Expect = 2e-09
Identities = 53/203 (26%), Positives = 90/203 (44%), Gaps = 21/203 (10%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 69
KA LR+ I ++ + EE+ +++ + H + +A Y+S +EI+T PL++
Sbjct: 28 KATLRHHILSRRKRVPAEERGAAGELLVRRFPAHM-IQDGPTVAAYVSMGSEIETRPLLR 86
Query: 70 HIQARGAAAFVPQYAGG------------RMRMLHLETGDEQTMPKTKHGISQHGKDQAR 117
++A G VP+ G +R + G + H D+
Sbjct: 87 WLRAHGCHVLVPRLGSGLEIGWSVLDSLESLRSMDAVGGANNAGSCSSPSTVHHRPDEPT 146
Query: 118 DDALETGGL---DLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNC 174
L L DL+IAP +A G+RLG G G+YD+ + R P A ++AV +
Sbjct: 147 GAVLPPEALEKADLVIAPALAVDPQGNRLGRGAGWYDRALA--RRKP--ACPLIAVCWPW 202
Query: 175 QVVD-EVPTNEQDQKVDEVIFAE 196
+V+D ++P D D V+ E
Sbjct: 203 EVLDIDLPAEPHDVPADGVLTPE 225
>UniRef50_Q830J1 Cluster: 5-formyltetrahydrofolate cyclo-ligase
family protein; n=1; Enterococcus faecalis|Rep:
5-formyltetrahydrofolate cyclo-ligase family protein -
Enterococcus faecalis (Streptococcus faecalis)
Length = 180
Score = 64.5 bits (150), Expect = 2e-09
Identities = 36/131 (27%), Positives = 65/131 (49%), Gaps = 10/131 (7%)
Query: 27 EEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQARGAAAFVPQ-YAG 85
E K+ + +YE++ ++ + I + S E+ T P+ + VP+ + G
Sbjct: 22 EIKQHKESSLYEQLFASQQWQQAQTIGMIRSLPLELSTQPIFERAMQESKQVAVPRTFKG 81
Query: 86 GRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALE--TGGLDLIIAPGVAFSRSGDRL 143
G+M Q P+T + S G ++ A E +DL+I PG+ F+R+G R+
Sbjct: 82 GKMHFY-------QVFPETVYDTSAFGVEEPPLTAAEITATAIDLLIVPGIVFNRAGYRI 134
Query: 144 GHGGGYYDKFI 154
G GGG+YD+++
Sbjct: 135 GFGGGFYDRYL 145
>UniRef50_Q8Y7E7 Cluster: Lmo1336 protein; n=13; Listeria|Rep:
Lmo1336 protein - Listeria monocytogenes
Length = 179
Score = 64.1 bits (149), Expect = 2e-09
Identities = 36/149 (24%), Positives = 77/149 (51%), Gaps = 3/149 (2%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 69
K L+R +I + ++ E + +S + EK+ ++++ + + ++ EI+T +I
Sbjct: 4 KRLIREKILRNLNSIDKVEHRERSIKLAEKLFLLPEWENAKVVGITLARHPEIETEAIIL 63
Query: 70 HIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLI 129
+ G +P+ +M + + K+K GI + + + ++ +DL+
Sbjct: 64 QAKKEGKTILIPKTYYPSRKMEFKKMDSIHPLIKSKFGILEPNE---LAETVDKKVIDLL 120
Query: 130 IAPGVAFSRSGDRLGHGGGYYDKFITNLR 158
I PGVAF++ R+G GGG+YD+F+T+ +
Sbjct: 121 IVPGVAFNKDHYRIGFGGGFYDRFLTDFQ 149
>UniRef50_Q5ZXY7 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=4; Legionella pneumophila|Rep:
5-formyltetrahydrofolate cyclo-ligase - Legionella
pneumophila subsp. pneumophila (strain Philadelphia 1
/ATCC 33152 / DSM 7513)
Length = 193
Score = 64.1 bits (149), Expect = 2e-09
Identities = 52/184 (28%), Positives = 78/184 (42%), Gaps = 8/184 (4%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 69
K LRN I + L+ + S + ++ + Y+ + RIALY + E+D L K
Sbjct: 6 KVALRNTIKQVRSKLSVPYRTASSNQICTRIRSLEQYRQAKRIALYFAVNGEVDLTFLWK 65
Query: 70 HIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLI 129
+G + P + L K+ I + D + AL LDLI
Sbjct: 66 SAPLQGKYCYFP-VLNNDSTLSFLPATPSTPFKTNKYDIPEPDVDI--ELALPIDELDLI 122
Query: 130 IAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQKV 189
I P VAF RLG G GYYD+ + N ++ ++ VA+ Q VD + D +
Sbjct: 123 IMPLVAFDAHCTRLGMGSGYYDRTLAN-----KSKAHLLGVAYQFQRVDYIEPRPWDVPL 177
Query: 190 DEVI 193
D VI
Sbjct: 178 DAVI 181
>UniRef50_A1BG38 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Chlorobium phaeobacteroides DSM 266|Rep:
5-formyltetrahydrofolate cyclo-ligase - Chlorobium
phaeobacteroides (strain DSM 266)
Length = 216
Score = 64.1 bits (149), Expect = 2e-09
Identities = 48/186 (25%), Positives = 85/186 (45%), Gaps = 9/186 (4%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYM--STENEIDTAPL 67
K LR +I A+ LT E ++S+ + + V + + Y+ + E+DT+ L
Sbjct: 26 KQTLRKKILAERLLLTEEVWLQKSREIADAVQRLPEFPLFRHVLGYLPLADRREVDTSEL 85
Query: 68 IKHIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLD 127
+ G +P AGG + + D + + G S+ + D+ LD
Sbjct: 86 FALLARFGKQVSIPVIAGGEL--VTAAYRDHEPLTTGIFGQSEPLRPVMSDER----SLD 139
Query: 128 LIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQ 187
++ P VA G RLG+G G+YD+F + L E P + +AF Q++ +P + DQ
Sbjct: 140 AVLVPVVAADHRGYRLGYGKGFYDRFFSRL-AKAECNPLRIGLAFYMQILPRIPVDPWDQ 198
Query: 188 KVDEVI 193
+D ++
Sbjct: 199 PLDYIV 204
>UniRef50_A6S3W0 Cluster: Putative uncharacterized protein; n=5;
Pezizomycotina|Rep: Putative uncharacterized protein -
Botryotinia fuckeliana B05.10
Length = 246
Score = 64.1 bits (149), Expect = 2e-09
Identities = 54/173 (31%), Positives = 82/173 (47%), Gaps = 23/173 (13%)
Query: 9 AKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTEN-EIDTAPL 67
+K LR I ++ +TNE QS V ++IN Y+ + RI +Y++ E+ T +
Sbjct: 10 SKKELRLSIKKLLSTVTNESVHAQSAAVLHRLINFQPYQQAKRIGIYLAMPTGELQTDAI 69
Query: 68 IKHIQARGAAAFVP-----QYAG-----GRMRMLHLET-GDEQTMPKTKHGISQHGKDQA 116
++H G FVP Y M M+ L + D + + + GI +
Sbjct: 70 VRHALESGKQVFVPYLHKSSYQSPDTPRSVMDMVDLRSLADFEALKRDSWGIPTIPAETV 129
Query: 117 --RDDALET----GGLDLIIAPGVAFS---RSG--DRLGHGGGYYDKFITNLR 158
R+ L+T GGLD+I+ PGVAF +S RLGHG G+YD F+ R
Sbjct: 130 GERESILKTVSSKGGLDMILLPGVAFDIDPKSSFIRRLGHGKGFYDYFLHRYR 182
>UniRef50_A1CDT2 Cluster: 5-formyltetrahydrofolate cyclo-ligase,
putative; n=6; Trichocomaceae|Rep:
5-formyltetrahydrofolate cyclo-ligase, putative -
Aspergillus clavatus
Length = 243
Score = 64.1 bits (149), Expect = 2e-09
Identities = 63/228 (27%), Positives = 103/228 (45%), Gaps = 40/228 (17%)
Query: 9 AKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTEN-EIDTAPL 67
AK LR +I + + QS++ +K+ + + Y+++ RI +Y+S + E+ T +
Sbjct: 8 AKRDLRKKIRDVLQNTPTDSIINQSRVAADKLFSLTEYQNAKRIGVYLSMPSGELSTTAI 67
Query: 68 IKHIQARGAAAFVP-----------QYAGGRMRMLHLETGDEQT-MPKTKHGISQHGKDQ 115
++ + G FVP Q M ML L++ E T + K GI K Q
Sbjct: 68 VQDALSNGKEVFVPYIHSVESASSAQQKTSIMDMLVLQSMHEFTSLEPDKWGIPSLTKTQ 127
Query: 116 ARD--------------DALETG---GLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNL- 157
+ + + T GLDLI+ PG+AF + RLGHG GYYD F+T
Sbjct: 128 VANKRNCFGEIGVSTTPEEVSTASLEGLDLIVMPGMAFDQGFRRLGHGKGYYDHFLTRYS 187
Query: 158 ------RLNPETAPKIVAVAFNCQVV---DEVPTNEQDQKVDEVIFAE 196
+ P +VA+A Q++ +E+P + D VD +I +
Sbjct: 188 KKQAKSKTTTSKMPLLVALALKEQMLPLTEEIPVADHDWPVDMLIVGD 235
>UniRef50_Q5FIZ8 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Lactobacillus acidophilus|Rep:
5-formyltetrahydrofolate cyclo-ligase - Lactobacillus
acidophilus
Length = 187
Score = 63.3 bits (147), Expect = 4e-09
Identities = 44/141 (31%), Positives = 71/141 (50%), Gaps = 8/141 (5%)
Query: 25 TNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQARGAAAFVPQYA 84
T EEKK + ++ EK++ + K+S I + S E+DT+ LI + G ++ +
Sbjct: 19 TTEEKKIEDAVLLEKLMGTNLIKNSQTIGVTASMPFEVDTSELIARLWDLGKEVYLAKAR 78
Query: 85 GGRMRML-HLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLIIAPGVAFSR-SGDR 142
+ L L + K+K G+ ++ A A LDL+I PG+ F+ S R
Sbjct: 79 TDQNHTLDFLHYTYMSKLVKSKFGV----EEIADKSAKVNNELDLVIVPGLLFATDSHVR 134
Query: 143 LGHGGGYYDKFITNLRLNPET 163
+G GGGYYD+F+ + NP T
Sbjct: 135 IGFGGGYYDRFLA--KYNPRT 153
>UniRef50_Q1MQA3 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Lawsonia intracellularis PHE/MN1-00|Rep:
5-formyltetrahydrofolate cyclo-ligase - Lawsonia
intracellularis (strain PHE/MN1-00)
Length = 193
Score = 63.3 bits (147), Expect = 4e-09
Identities = 43/148 (29%), Positives = 70/148 (47%), Gaps = 4/148 (2%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 69
K +RN + AL++EE S+I+ K+ N ++ + +ALY S +NE+ T L++
Sbjct: 6 KDFVRNSCIIRRQALSSEEVHSASRIIAAKLFNDDVWRRARSVALYSSIKNEVSTESLLR 65
Query: 70 HIQARGAAAFVPQ-YAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGL-D 127
G +P+ G + + + GI + D R A+ L +
Sbjct: 66 QAWQEGKQVLLPRCILSGEPELEFALCRGWEELVVGPFGILE--PDYKRCIAVSGKNLPE 123
Query: 128 LIIAPGVAFSRSGDRLGHGGGYYDKFIT 155
LII P V + G RLG+G GYYDK ++
Sbjct: 124 LIIVPAVGLTSFGARLGYGKGYYDKLLS 151
>UniRef50_A4AI88 Cluster: 5-formyltetrahydrofolate
cyclo-ligase-related protein; n=3; Actinobacteria
(class)|Rep: 5-formyltetrahydrofolate
cyclo-ligase-related protein - marine actinobacterium
PHSC20C1
Length = 196
Score = 63.3 bits (147), Expect = 4e-09
Identities = 51/185 (27%), Positives = 81/185 (43%), Gaps = 10/185 (5%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 69
K LR E+ + T +E+ V +I + S+ +A Y+ST +E T ++
Sbjct: 9 KRALRAELRERRRICTAKERDESEAGVTANLIELATRLGSTSVAAYLSTTDEPQTRGFLR 68
Query: 70 HIQARGAAAFVP-QYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDL 128
+P A G + + G+E+ K I + +DL
Sbjct: 69 WACEHDIRVLLPISRADGLLDWAPYD-GEEED----KDLIGMPAPTSEVLGPIAINDVDL 123
Query: 129 IIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQK 188
II P + R+G R+G G GY+DK + ++ ET P I AV F + VD VPT DQ
Sbjct: 124 IIVPAASVDRTGMRMGWGRGYFDKTLGSM----ETKPPIYAVIFESEYVDAVPTELHDQP 179
Query: 189 VDEVI 193
V+ ++
Sbjct: 180 VNGIV 184
>UniRef50_A1KWH4 Cluster: Putative uncharacterized protein; n=4;
Neisseria|Rep: Putative uncharacterized protein -
Neisseria meningitidis serogroup C / serotype 2a (strain
ATCC 700532 /FAM18)
Length = 219
Score = 63.3 bits (147), Expect = 4e-09
Identities = 45/185 (24%), Positives = 80/185 (43%), Gaps = 6/185 (3%)
Query: 7 NPAKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAP 66
N K LR E+ + + + + + + + +++ + K +I +Y E+
Sbjct: 29 NEEKHALRRELRGRRSQM-GWDVRAAATVKINRLLKR-YIKHGRKIGVYWPMGKELRLDG 86
Query: 67 LIKHIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTK-HGISQHGKDQARDDALETGG 125
++ Q RGA ++P Y R R + E M + + G ++ Q + G
Sbjct: 87 FVRAAQKRGAKLYLP-YIEPRSRRMWFTPYPESGMERERIRGRARLNVPQFAGRKIRVHG 145
Query: 126 LDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQ 185
L +++ P V R G RLG GGYYD + ++ + K V V F CQ+VD +
Sbjct: 146 LSVLLVPLVGIDREGYRLGQAGGYYDATLAAMKYRLQA--KTVGVGFACQLVDRLSVEAH 203
Query: 186 DQKVD 190
D +D
Sbjct: 204 DLPLD 208
>UniRef50_A2SSS2 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Methanocorpusculum labreanum Z|Rep:
5-formyltetrahydrofolate cyclo-ligase -
Methanocorpusculum labreanum (strain ATCC 43576 / DSM
4855 / Z)
Length = 196
Score = 63.3 bits (147), Expect = 4e-09
Identities = 46/186 (24%), Positives = 90/186 (48%), Gaps = 14/186 (7%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 69
KA LR + + AL+ +++ + + ++ K + Y++ + E+++ ++
Sbjct: 4 KAELRTILKERREALSLGDRREKGYYITCRL--QELLKPYHTVLAYIAKDPEVESMVIVN 61
Query: 70 HIQARGAAAFVP--QYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLD 127
+ G VP + +R+ +L T +Q P G + + + +D
Sbjct: 62 CLLEEGKTVVVPIIEKETHTLRLSYL-TSMDQLEP----GTFRVPEPLTHEQPAPASSID 116
Query: 128 LIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQ 187
+++ P V F R+G RLG+G GYYD+F NP+ P+I +A+ CQ V+ +PT D
Sbjct: 117 VVLVPMVGFDRAGHRLGYGAGYYDRFFEK---NPD-IPRI-GMAYACQEVELIPTEPFDA 171
Query: 188 KVDEVI 193
++D V+
Sbjct: 172 RMDYVV 177
>UniRef50_Q7VRG0 Cluster: Ligase;5-formyltetrahydrofolate
cycloligase family; n=2; Candidatus Blochmannia|Rep:
Ligase;5-formyltetrahydrofolate cycloligase family -
Blochmannia floridanus
Length = 195
Score = 62.9 bits (146), Expect = 5e-09
Identities = 40/146 (27%), Positives = 71/146 (48%), Gaps = 2/146 (1%)
Query: 7 NPAKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAP 66
N K +R+ I + +L E+ + +Q++ K+IN ++ I +Y+S + EI T
Sbjct: 2 NLNKKAIRSYIRSLRQSLNYSEQYKSAQLITNKIINLDCIHKATHIGIYISFDGEIYTDL 61
Query: 67 LIKHIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGL 126
LIK + + ++P + +L + P ++ ++ + D + L
Sbjct: 62 LIKFLLSMKKKIYIPVLLHKQQHLLFAPY--TLSTPTIQNYLNVYEPKYNIIDLISLDKL 119
Query: 127 DLIIAPGVAFSRSGDRLGHGGGYYDK 152
D+I P VAF G+RLG GGG+YDK
Sbjct: 120 DIIFIPLVAFDDHGNRLGMGGGFYDK 145
>UniRef50_A7JX05 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=2; Pasteurellaceae|Rep: 5-formyltetrahydrofolate
cyclo-ligase - Mannheimia haemolytica PHL213
Length = 192
Score = 62.9 bits (146), Expect = 5e-09
Identities = 46/189 (24%), Positives = 92/189 (48%), Gaps = 16/189 (8%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 69
++ LR + K +LT ++ + ++ + + ++ +S IA Y+ EI PL++
Sbjct: 10 RSQLRQSMRLKRQSLTAGQQTQAAESIIPQALSLIESYQASHIAFYLPFNGEISPIPLME 69
Query: 70 HIQARGAAAFVP---QYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGL 126
+ +G ++P + G++ L + + + + GI + D + L L
Sbjct: 70 QLLQQGKKLYLPLLHPFTSGQL--LFVNYNCKTILKFNRLGIQEPILDVR--NILPLQEL 125
Query: 127 DLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAV--AFNCQVVDEVPTNE 184
++I P VA ++G+RLG GGG+YD+ + AP +++V A CQ V+++P
Sbjct: 126 EMIFTPLVACDKAGNRLGMGGGFYDRTLAQ-------APHLISVGLAHECQQVEQLPIES 178
Query: 185 QDQKVDEVI 193
D +D +I
Sbjct: 179 WDMPLDHII 187
>UniRef50_A4SEK3 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Prosthecochloris vibrioformis DSM 265|Rep:
5-formyltetrahydrofolate cyclo-ligase - Prosthecochloris
vibrioformis DSM 265
Length = 200
Score = 62.9 bits (146), Expect = 5e-09
Identities = 46/142 (32%), Positives = 69/142 (48%), Gaps = 7/142 (4%)
Query: 52 IALYMSTENEIDTAPLIKHIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQH 111
I L M + E+DTAPLI+ + A VP G M LE E + + G Q
Sbjct: 50 IYLPMKAKGELDTAPLIELLLAMKKTVMVPVVKGSDMVSAILEASVE--LQPSPLGNLQP 107
Query: 112 GKDQARDDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVA 171
D++ LD ++ P VA R G RLG G GYYD+F++ L P + A
Sbjct: 108 CHLVPADESR----LDAVLLPLVAVDRCGRRLGFGKGYYDRFLSRLS-REGFRPWRIGYA 162
Query: 172 FNCQVVDEVPTNEQDQKVDEVI 193
++ Q+ D +P++ DQ +D ++
Sbjct: 163 YSFQMTDCIPSDPWDQNLDILV 184
>UniRef50_Q03UF8 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Leuconostoc mesenteroides subsp. mesenteroides ATCC
8293|Rep: 5-formyltetrahydrofolate cyclo-ligase -
Leuconostoc mesenteroides subsp. mesenteroides (strain
ATCC 8293 /NCDO 523)
Length = 177
Score = 62.1 bits (144), Expect = 8e-09
Identities = 36/124 (29%), Positives = 69/124 (55%), Gaps = 9/124 (7%)
Query: 28 EKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQARGAAAFVPQYAGGR 87
E++R I++ K +++ +S+ +A+ +S E+E+ T +I+ VP+ + G+
Sbjct: 26 EEERLQAILFSK----AYWNNSNSVAVTISMEHELSTDVIIQEALRSHKKVVVPRVSSGK 81
Query: 88 MRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLIIAPGVAFSRSGDRLGHGG 147
+ E M K+K GI + +D+ + L+ G+DL++ PGVAFS R+G+G
Sbjct: 82 LLWFDYI---ESLMSKSKFGILEPTQDENQAQNLK--GIDLMVVPGVAFSEDNYRIGYGA 136
Query: 148 GYYD 151
G++D
Sbjct: 137 GFFD 140
>UniRef50_A3VP85 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Parvularcula bermudensis HTCC2503|Rep:
5-formyltetrahydrofolate cyclo-ligase - Parvularcula
bermudensis HTCC2503
Length = 159
Score = 62.1 bits (144), Expect = 8e-09
Identities = 43/141 (30%), Positives = 63/141 (44%), Gaps = 7/141 (4%)
Query: 50 SRIALYMSTENEIDTAPLIKHIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGIS 109
S IALY E+DTAPL K + RG A +P + ++ + + + GI
Sbjct: 10 SAIALYAPKGQELDTAPLAKRLSERGHAILLPVVTAQDAPLEFRLWEIDRPLVEGRFGIP 69
Query: 110 QHGKDQARDDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVA 169
D + +I+ P +A G RLGHGGGYYD+ ++ LR A +
Sbjct: 70 VPPADSPKRLP------QIIVTPLLAVRPDGARLGHGGGYYDRTLSALRTEGPGA-LAIG 122
Query: 170 VAFNCQVVDEVPTNEQDQKVD 190
+ QV+D P DQ +D
Sbjct: 123 YGYEGQVMDRFPVETHDQFLD 143
>UniRef50_Q8NS05 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=3; Corynebacterium|Rep: 5-formyltetrahydrofolate
cyclo-ligase - Corynebacterium glutamicum
(Brevibacterium flavum)
Length = 190
Score = 61.7 bits (143), Expect = 1e-08
Identities = 51/184 (27%), Positives = 84/184 (45%), Gaps = 12/184 (6%)
Query: 14 RNEIAAKIA-ALTNEEKKRQSQIVYEKVINHSWY---KSSSRIALYMSTENEIDTAPLIK 69
+ E+ K+ A TN ++ +++ + N S+Y K RIA Y+ E L+
Sbjct: 5 KQELRTKLREARTNMDEASRTRENAAIIANVSYYIRSKQPKRIAAYVPVRTEPGGRLLLD 64
Query: 70 HIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLI 129
+ A +A +P R L G +P GI + G + +AL DL+
Sbjct: 65 ALHAETSALILPVSLEDRRLDWALYEGPTSLVPGA-FGIQEPGGTRLGPEALNF--CDLV 121
Query: 130 IAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQKV 189
IAP +A + SG RLG GGG+YD+ L ++ + FN ++ D++ E D V
Sbjct: 122 IAPALACTPSGIRLGKGGGFYDR-----ALATGVKADVITLLFNGEIRDDIEVEEHDLPV 176
Query: 190 DEVI 193
+ +I
Sbjct: 177 NVII 180
>UniRef50_A6G5C7 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Plesiocystis pacifica SIR-1|Rep:
5-formyltetrahydrofolate cyclo-ligase - Plesiocystis
pacifica SIR-1
Length = 214
Score = 61.7 bits (143), Expect = 1e-08
Identities = 42/151 (27%), Positives = 75/151 (49%), Gaps = 11/151 (7%)
Query: 10 KALLRNEIAAKIAALTNEEKK----RQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTA 65
K LR + A+ L E + +++V + + + W +++ +A ++ E DT
Sbjct: 8 KIALRQRVLARRKQLRRAEPEVLASASARLVAQVLADARW-RAARGVAAFVGVRGEPDTW 66
Query: 66 PLIKHIQARGAAAFVPQYAGGRMRMLHL-ETGDEQTMPKTKHGI---SQHGKDQARDDAL 121
L++ + G ++P+ G RM L E D + + + K G+ ++ G+
Sbjct: 67 ALLEQTLSAGKGLWLPRVDGPRMVFWELREPADLEALERRKMGLREPAERGRSSPAPGPA 126
Query: 122 ETGGLDLIIAPGVAFSRSGDRLGHGGGYYDK 152
E G+DLI+ PG+AFS G RLG G G+YD+
Sbjct: 127 E--GVDLILVPGLAFSPGGLRLGFGAGHYDR 155
>UniRef50_Q89AD6 Cluster: Uncharacterized protein bbp_370; n=1;
Buchnera aphidicola (Baizongia pistaciae)|Rep:
Uncharacterized protein bbp_370 - Buchnera aphidicola
subsp. Baizongia pistaciae
Length = 195
Score = 61.7 bits (143), Expect = 1e-08
Identities = 40/153 (26%), Positives = 78/153 (50%), Gaps = 5/153 (3%)
Query: 24 LTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQARGAAAFVPQY 83
+ N+ +++ + + +K+ + S IA++ S + EIDT PLI + + ++P
Sbjct: 20 INNKIREQLAISISKKIFYCNILDSVKNIAIFCSFDGEIDTYPLILKLWRQNYNVYLPII 79
Query: 84 AGGRMRML-HLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLIIAPGVAFSRSGDR 142
++L ++ ++ K + I + D R + +++ LD++ P VAF G R
Sbjct: 80 NYNYKKILGFMKYLPNTSLIKNRFNILEPVFD--RKNFIQSDDLDIMFVPLVAFDEFGYR 137
Query: 143 LGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQ 175
LG GGG+YD+ + N + P + +AF+CQ
Sbjct: 138 LGMGGGFYDRILINYDIKKSFFP--IGLAFDCQ 168
>UniRef50_Q5QVB4 Cluster: 5-formyltetrahydrofolate cyclo-ligase
family protein; n=2; Idiomarina|Rep:
5-formyltetrahydrofolate cyclo-ligase family protein -
Idiomarina loihiensis
Length = 195
Score = 61.3 bits (142), Expect = 1e-08
Identities = 43/189 (22%), Positives = 84/189 (44%), Gaps = 9/189 (4%)
Query: 12 LLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSS------SRIALYMSTENEIDTA 65
+ R+ + K+ + Q Q +V N + S + +A+Y S + E+ T
Sbjct: 1 MTRHNLRRKLQQIRRNLPAEQQQTAAREVANRLQQRLSHLQPEQTTVAVYKSFDGELPTF 60
Query: 66 PLIKHIQARGAAAFVPQ-YAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETG 124
P+I+ + G +P + + +L L + M K+GI + + + +
Sbjct: 61 PVIETLWQLGFNTVLPVLHPFAKGHLLFLRYTPDTPMTLNKYGIQE--PELNVQNMVPLS 118
Query: 125 GLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNE 184
+ +++ P V F ++G+RLG GGGYYD+ + + +++N Q V+ +P
Sbjct: 119 NIQILLMPLVGFDQNGNRLGMGGGYYDRTLAQWHNGNRPNLFPIGLSYNQQQVEHIPVES 178
Query: 185 QDQKVDEVI 193
D + EVI
Sbjct: 179 WDIPLPEVI 187
>UniRef50_Q8K9E3 Cluster: Uncharacterized protein BUsg_396; n=1;
Buchnera aphidicola (Schizaphis graminum)|Rep:
Uncharacterized protein BUsg_396 - Buchnera aphidicola
subsp. Schizaphis graminum
Length = 199
Score = 61.3 bits (142), Expect = 1e-08
Identities = 50/175 (28%), Positives = 84/175 (48%), Gaps = 6/175 (3%)
Query: 13 LRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQ 72
+R+ I ++T +K +S + N + ++ IA ++S + EI+T PLI +
Sbjct: 12 IRSYIRIVRNSVTLTKKYDESNKIVRTAFNCNIIYNAKNIACFLSFDGEINTYPLILKLW 71
Query: 73 ARGAAAFVPQYAGGRMRMLHLETGD-EQTMPKTKHGISQHGKDQARDDALETGGLDLIIA 131
F+P + R L + + ++ I Q + +D LE+ LDLII
Sbjct: 72 LNNKNVFLPIVSSSYSRKLFFVPFTCKSILYYNQYNILQPFYNM-KDIILESD-LDLIIV 129
Query: 132 PGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQD 186
P VAF G RLG GGG+YD+F+ N + P + +A++ Q V+ +P D
Sbjct: 130 PLVAFDCRGVRLGMGGGFYDQFLKNWE-RKKFIP--IGMAYDFQFVNYIPRQPWD 181
>UniRef50_Q8EQ05 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Oceanobacillus iheyensis|Rep:
5-formyltetrahydrofolate cyclo-ligase - Oceanobacillus
iheyensis
Length = 186
Score = 60.9 bits (141), Expect = 2e-08
Identities = 46/185 (24%), Positives = 85/185 (45%), Gaps = 10/185 (5%)
Query: 10 KALLRNEIAAKIAALTNEEKKR-QSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLI 68
K +LR + ++ L+ + +K QS+ + +H W K+S I + +S E DT +I
Sbjct: 3 KQILRKNMIQQLNELSQDRRKSIQSKQQHLLFHSHLW-KNSLTIGITVSKGFEWDTKQII 61
Query: 69 KHIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDL 128
+ VP+ M + + + + GI + + LE L L
Sbjct: 62 QQGWKENKVIAVPKCNPIDKTMTYRQITSFEQLEVVYAGIEEPIMEHT--SPLENELLGL 119
Query: 129 IIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQK 188
I PG+ F ++G R+G GGGYYD+ + +++ AP + ++ Q++ +P D
Sbjct: 120 CIVPGIVFDKNGYRIGFGGGYYDRILPSIQ-----APTL-SICSEVQIISSIPKESHDLS 173
Query: 189 VDEVI 193
VD ++
Sbjct: 174 VDYLL 178
>UniRef50_A2RHQ0 Cluster: 5-formyltetrahydrofolate cyclo-ligase
family protein; n=2; Lactococcus lactis|Rep:
5-formyltetrahydrofolate cyclo-ligase family protein -
Lactococcus lactis subsp. cremoris (strain MG1363)
Length = 177
Score = 60.9 bits (141), Expect = 2e-08
Identities = 41/143 (28%), Positives = 75/143 (52%), Gaps = 11/143 (7%)
Query: 14 RNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQA 73
R +I + ++ EK Q++ V E++ S +KS+ +IALYMS E + L Q+
Sbjct: 8 RKKILQMLKKFSDYEKGCQNKEVLEQLTASSDWKSAKKIALYMSMPIEFNLTELFD--QS 65
Query: 74 RGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLIIAPG 133
+P+ R +M+ + D++ + ++K G+ + D A + D I+ PG
Sbjct: 66 DDKEILIPKCLPQR-QMIFAKY-DKENLVRSKFGLLEPKSDLAIEP-------DFILVPG 116
Query: 134 VAFSRSGDRLGHGGGYYDKFITN 156
+ ++ G R+G GGGYYD+++ N
Sbjct: 117 LIWNDEGHRIGFGGGYYDRYLAN 139
>UniRef50_Q2SN29 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Hahella chejuensis KCTC 2396|Rep:
5-formyltetrahydrofolate cyclo-ligase - Hahella
chejuensis (strain KCTC 2396)
Length = 190
Score = 60.5 bits (140), Expect = 3e-08
Identities = 45/170 (26%), Positives = 82/170 (48%), Gaps = 8/170 (4%)
Query: 20 KIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQARGAAAF 79
K ALT +++ + + + + + S+R LY++ + EI+ P I+ + R A +
Sbjct: 4 KRRALTPAQQRSAASGLQKSLSSAIHLSRSARWGLYLANDGEINPLPTIQRLWRRKKACY 63
Query: 80 VP---QYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLIIAPGVAF 136
+P R+ + E G + + K+GI + A+ + L ++ P VAF
Sbjct: 64 LPVLHPLYHNRLWFVRYEPGTK--LKPNKYGIPEPVLRGAK--RVPPWSLHVVCFPLVAF 119
Query: 137 SRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQD 186
+ G+RLG GGGYYD+ + R+ + PK++ A + Q E+P D
Sbjct: 120 DKQGNRLGMGGGYYDRTFADRRVIIK-RPKLIGFAHHFQQFPELPHEPWD 168
>UniRef50_Q3VT50 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Prosthecochloris aestuarii DSM 271|Rep:
5-formyltetrahydrofolate cyclo-ligase - Prosthecochloris
aestuarii DSM 271
Length = 197
Score = 60.5 bits (140), Expect = 3e-08
Identities = 47/186 (25%), Positives = 87/186 (46%), Gaps = 10/186 (5%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMS--TENEIDTAPL 67
K+ +R + A +AL+ + + +S+ + K++ + ++ +Y+ E+DT+
Sbjct: 11 KSAVRRRMIALRSALSRHDWELRSRALTAKLLCLDSVVRAEQVMIYLPFVARREVDTSMF 70
Query: 68 IKHIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLD 127
+ ++A VP G + GD + G G+ + D
Sbjct: 71 MSWLEAEQKTVSVPVVKGKDLVASRFHVGD-----RIVSGC--FGQPEPAIVRPLPVVAD 123
Query: 128 LIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQ 187
+II P VA RSG R+G+G G YD+F L+ T P V + F+ QV+D +P + D+
Sbjct: 124 VIIVPLVAADRSGTRIGYGAGCYDRFFAALQKRGFT-PHAVGICFSFQVLDTLPFDPWDR 182
Query: 188 KVDEVI 193
K+D ++
Sbjct: 183 KLDCIV 188
>UniRef50_Q1V201 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=2; Candidatus Pelagibacter ubique|Rep:
5-formyltetrahydrofolate cyclo-ligase - Candidatus
Pelagibacter ubique HTCC1002
Length = 182
Score = 60.5 bits (140), Expect = 3e-08
Identities = 27/67 (40%), Positives = 44/67 (65%), Gaps = 2/67 (2%)
Query: 127 DLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQD 186
D+++ P VAF ++ +RLG+GGGYYD+ I L + +AF+ Q +D+VPTN D
Sbjct: 111 DVLLIPLVAFDKNLNRLGYGGGYYDRLIEKLSKKKNIIK--IGLAFSIQEIDKVPTNMYD 168
Query: 187 QKVDEVI 193
+K+D ++
Sbjct: 169 KKLDYIV 175
>UniRef50_A1AXM1 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=3; Bacteria|Rep: 5-formyltetrahydrofolate cyclo-ligase
- Ruthia magnifica subsp. Calyptogena magnifica
Length = 185
Score = 60.5 bits (140), Expect = 3e-08
Identities = 40/182 (21%), Positives = 85/182 (46%), Gaps = 9/182 (4%)
Query: 13 LRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQ 72
LR + K A+ + +++ ++ + + +K +IA+Y+ + EIDT + ++
Sbjct: 4 LRLTLRQKRRAINHSNREKLAKRLLSQTQRLVTFKHGQKIAIYLPNDGEIDTKYIYNFLK 63
Query: 73 ARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLIIAP 132
+G + ++P ++ + + K I K+ L +++I P
Sbjct: 64 RQGFSIYLPILVNKSLKFSKIN----KHFKKNIFSI----KEPVFTQILSAKQINIIFMP 115
Query: 133 GVAFSRSGDRLGHGGGYYDKFITNLRLNPE-TAPKIVAVAFNCQVVDEVPTNEQDQKVDE 191
V F ++ +R+G GGG+YD+ +T + PK+ +AF+CQ V + N D ++
Sbjct: 116 LVGFDKNKNRIGMGGGFYDRTLTFKKPQQNYKNPKLYGLAFDCQKVYRLNANPWDVPLNA 175
Query: 192 VI 193
+I
Sbjct: 176 II 177
>UniRef50_A5IZ16 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=3; Mycoplasma|Rep: 5-formyltetrahydrofolate
cyclo-ligase - Mycoplasma agalactiae
Length = 184
Score = 60.1 bits (139), Expect = 3e-08
Identities = 49/185 (26%), Positives = 85/185 (45%), Gaps = 11/185 (5%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 69
K LR + AK LT E K + + VI +I +Y+ T+ E DT+ +I+
Sbjct: 3 KRELRKLMIAKRKELTPEYKTNANLAISTSVIYFINKNRFKQICIYLPTKYETDTSKIIE 62
Query: 70 HIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDAL-ETGGLDL 128
+VP+ ++ L +T + ++ ++++ D L +D
Sbjct: 63 WCLHNNIKVYVPKVLEDNKMVMTLIDN------RTDYQLNLFNINESKSDILCNIEEIDC 116
Query: 129 IIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQK 188
+ P VAF S +R+G G G+YD+F + N KI + FN Q+V+++ + DQ
Sbjct: 117 VFTPLVAFDNSLNRIGMGKGFYDRFFSE---NNGNYLKI-GLCFNDQLVEKIESETSDQM 172
Query: 189 VDEVI 193
+D VI
Sbjct: 173 LDLVI 177
>UniRef50_A0RTU2 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Cenarchaeum symbiosum|Rep: 5-formyltetrahydrofolate
cyclo-ligase - Cenarchaeum symbiosum
Length = 173
Score = 60.1 bits (139), Expect = 3e-08
Identities = 44/148 (29%), Positives = 70/148 (47%), Gaps = 13/148 (8%)
Query: 46 YKSSSRIALYMSTENEIDTAPLIKHIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTK 105
+ + +A Y S +E+ T L++ + G +P G + + E D + K
Sbjct: 31 FAKARSVACYYSMGSEVPTHTLMQGLLDSGRKVCLPSIPGEDL--VFREVRDLGRLESGK 88
Query: 106 HGISQHGKDQARDDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAP 165
I + R+D E D+II P V +R G RLG+G GYYD+F+ L + P
Sbjct: 89 FDIME-----PRNDCEECIDPDVIIVPAVGTARDGSRLGYGRGYYDRFLAGLDI-----P 138
Query: 166 KIVAVAFNCQVVDEVPTNEQDQKVDEVI 193
IV ++ Q+V VPT E D V+ ++
Sbjct: 139 SIVP-CYSKQLVKSVPTEEHDIPVNWIV 165
>UniRef50_UPI0000E0F49C Cluster: hypothetical
5-formyltetrahydrofolatecyclo-ligase-family protein;
n=1; alpha proteobacterium HTCC2255|Rep: hypothetical
5-formyltetrahydrofolatecyclo-ligase-family protein -
alpha proteobacterium HTCC2255
Length = 211
Score = 59.7 bits (138), Expect = 5e-08
Identities = 45/195 (23%), Positives = 87/195 (44%), Gaps = 14/195 (7%)
Query: 9 AKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLI 68
A+ LR E+ AK AL+ +E+ Q + + + + ++ IA Y+ + EI LI
Sbjct: 10 ARQALRAELRAKRRALSEQEQCHAQQQLLTQASD--FIHNADIIAAYLPNDGEISPQTLI 67
Query: 69 KHIQARGAAAFVPQ-YAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLD 127
+ A +P + +L + + M K K GI + D + ++
Sbjct: 68 DYAWAHNKTVALPVLHPFHPQTLLFVRYTSQSNMTKNKFGIPE--PQLTTQDIIPIHTIN 125
Query: 128 LIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPE---------TAPKIVAVAFNCQVVD 178
I P V F G+R+G GGG+YD+ + + + + T P ++ +A + Q++D
Sbjct: 126 RIFVPLVGFDDQGNRMGMGGGFYDRTLAPITESHQVGYVSFKISTPPTLIGLAHDVQMLD 185
Query: 179 EVPTNEQDQKVDEVI 193
+P + D + ++
Sbjct: 186 SIPCAQWDIPMSHIL 200
>UniRef50_Q1LSJ3 Cluster: 5-formyltetrahydrofolate cyclo-ligase
family protein; n=1; Baumannia cicadellinicola str. Hc
(Homalodisca coagulata)|Rep: 5-formyltetrahydrofolate
cyclo-ligase family protein - Baumannia cicadellinicola
subsp. Homalodisca coagulata
Length = 202
Score = 59.3 bits (137), Expect = 6e-08
Identities = 45/185 (24%), Positives = 91/185 (49%), Gaps = 9/185 (4%)
Query: 13 LRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQ 72
+R+ + + LT +++ + ++++ + + + ++++A+++S +NEI+T LI +
Sbjct: 10 IRDNVRMQRRMLTKKQQYQYAKMLALRALKDKRIQRANKLAIFLSFDNEINTNLLINMLW 69
Query: 73 ARGAAAFVP---QYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLI 129
++P +A G + L ++ + + I + D L LD+
Sbjct: 70 KETKIVYLPVLHPFAPGHL--LFMQYNPNTPLVINRLNIYEPQLDVTT--LLLLNQLDIC 125
Query: 130 IAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDE-VPTNEQDQK 188
P VAF G+RLG GGG+YD+ + + T I +A++CQ E +PT + D
Sbjct: 126 FIPLVAFDNYGNRLGMGGGFYDRMLYSWYTGEFTFCPI-GLAYDCQYQTEAIPTEKWDIP 184
Query: 189 VDEVI 193
+ EVI
Sbjct: 185 LPEVI 189
>UniRef50_Q47T07 Cluster: Putative uncharacterized protein; n=1;
Thermobifida fusca YX|Rep: Putative uncharacterized
protein - Thermobifida fusca (strain YX)
Length = 214
Score = 58.8 bits (136), Expect = 8e-08
Identities = 48/185 (25%), Positives = 81/185 (43%), Gaps = 7/185 (3%)
Query: 9 AKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLI 68
+K LR I A A + +E+ + + V+ S +A Y + +E DT L+
Sbjct: 25 SKRELRRRILAARRARSAQERAAAGLRIRDAVLELCAATGSPTVAAYYAVGSEPDTRSLV 84
Query: 69 KHIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDL 128
+ ARG +P + TG E P HG+ + + DA+ +
Sbjct: 85 AALAARGHRVLLPIVTPSGDLDWAVYTGPESLAP-AGHGLLEPTGTRLGADAVAEARV-- 141
Query: 129 IIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQK 188
++ P +A R+G RLG G G YD+ + +T +AV ++ ++VD VP D+
Sbjct: 142 LVCPALAADRAGYRLGRGAGCYDRVLA--AAGEQTLS--LAVVYDDELVDAVPVEPHDRP 197
Query: 189 VDEVI 193
V V+
Sbjct: 198 VRAVV 202
>UniRef50_Q2NB11 Cluster: Possible 5-formyltetrahydrofolate
cyclo-ligase; n=1; Erythrobacter litoralis HTCC2594|Rep:
Possible 5-formyltetrahydrofolate cyclo-ligase -
Erythrobacter litoralis (strain HTCC2594)
Length = 180
Score = 58.8 bits (136), Expect = 8e-08
Identities = 39/145 (26%), Positives = 72/145 (49%), Gaps = 14/145 (9%)
Query: 52 IALYMSTENEIDTAPLIKHIQARGAAAFVPQYAGGRMRML---HLETGDEQTMPKTKHGI 108
I LY +T +E T K RG +P+++ M H + DE + +
Sbjct: 38 IGLYHATADEAPTTSYTKFFYERGHRIALPRFSSANEPMTFAEHTDPFDESDLVAGPFEL 97
Query: 109 SQHGKDQARDDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIV 168
Q +D R LE D ++ P + F+ +G+RLG GGG+YD+++ + + + +
Sbjct: 98 RQPVEDAPR---LEP---DCLLIPLIGFTATGERLGQGGGHYDQWLADHQGRTK-----I 146
Query: 169 AVAFNCQVVDEVPTNEQDQKVDEVI 193
+A++ Q+V+ +P DQ++D V+
Sbjct: 147 GLAWDVQLVESLPIEPHDQRLDAVV 171
>UniRef50_A5CYV1 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Pelotomaculum thermopropionicum SI|Rep:
5-formyltetrahydrofolate cyclo-ligase - Pelotomaculum
thermopropionicum SI
Length = 203
Score = 58.8 bits (136), Expect = 8e-08
Identities = 40/143 (27%), Positives = 63/143 (44%), Gaps = 3/143 (2%)
Query: 13 LRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQ 72
LR ++ AAL +S + ++++ Y+ + I Y+ E+ T LI
Sbjct: 18 LRKKMLKARAALAPAGAAEKSARIVKRLVAMDEYRQARTIMSYVDFRGEVQTGDLIVRAM 77
Query: 73 ARGAAAFVPQY-AGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLIIA 131
A G VP GR L + GI + R ++ GLDL++
Sbjct: 78 ADGKRVAVPVTDMAGRQLKPSLLVDFPGDLEPNAWGIMEPKPRCLR--FVDPAGLDLVVV 135
Query: 132 PGVAFSRSGDRLGHGGGYYDKFI 154
PG+AF G RLG+G G+YD+F+
Sbjct: 136 PGLAFDLKGYRLGYGSGFYDRFL 158
>UniRef50_Q40JH2 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=5; canis group|Rep: 5-formyltetrahydrofolate
cyclo-ligase - Ehrlichia chaffeensis str. Sapulpa
Length = 180
Score = 58.0 bits (134), Expect = 1e-07
Identities = 29/67 (43%), Positives = 43/67 (64%), Gaps = 4/67 (5%)
Query: 127 DLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQD 186
+++I P +AF + +RLG GGGYYD I+ L+ N K++ VA++ Q+ D VPT D
Sbjct: 109 NILIVPLIAFDKCLNRLGFGGGYYDNTISKLKPN----CKVIGVAYDIQLCDIVPTESHD 164
Query: 187 QKVDEVI 193
Q +D VI
Sbjct: 165 QILDMVI 171
>UniRef50_Q3DVF9 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=2; Chloroflexus|Rep: 5-formyltetrahydrofolate
cyclo-ligase - Chloroflexus aurantiacus J-10-fl
Length = 193
Score = 58.0 bits (134), Expect = 1e-07
Identities = 55/185 (29%), Positives = 82/185 (44%), Gaps = 13/185 (7%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 69
KA LR + A+ AL + +++ S + V + + ++ I Y+ +E+DT PLI
Sbjct: 8 KAALRALMQARRDALADRDQR--SVRICALVQSLPVFTAARAIHCYVPMRSEVDTRPLIV 65
Query: 70 HIQARGAAAFVPQYAGGR-MRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDL 128
A G A VP G R +R + + E+ + G + R G L
Sbjct: 66 AALAAGKAVAVPVVGGQRELRHSWIASLSEEDWVPGRFGTRR----PRRLMPAYPGEWSL 121
Query: 129 IIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQK 188
I P +AF R RLG+GGGYYD + + V VAF Q V E+P D
Sbjct: 122 TIVPLLAFDRDLYRLGYGGGYYDALLAT------ASTVAVGVAFADQEVAELPREAHDYP 175
Query: 189 VDEVI 193
+D V+
Sbjct: 176 LDLVV 180
>UniRef50_Q73P08 Cluster: 5-formyltetrahydrofolate cyclo-ligase
family protein; n=1; Treponema denticola|Rep:
5-formyltetrahydrofolate cyclo-ligase family protein -
Treponema denticola
Length = 229
Score = 57.6 bits (133), Expect = 2e-07
Identities = 27/67 (40%), Positives = 42/67 (62%), Gaps = 1/67 (1%)
Query: 128 LIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVA-VAFNCQVVDEVPTNEQD 186
LI+ PG AFS+ G+R+G GGG+YD+F L + + +A + F+ Q++D +P E D
Sbjct: 153 LILVPGRAFSKKGERMGRGGGFYDRFFEKLFKSIKKEEVCLAGLCFSGQILDTIPMGEFD 212
Query: 187 QKVDEVI 193
VD V+
Sbjct: 213 HPVDLVV 219
>UniRef50_Q5PAS2 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=2; Anaplasma|Rep: 5-formyltetrahydrofolate
cyclo-ligase - Anaplasma marginale (strain St. Maries)
Length = 178
Score = 57.6 bits (133), Expect = 2e-07
Identities = 45/164 (27%), Positives = 77/164 (46%), Gaps = 21/164 (12%)
Query: 30 KRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQARGAAAFVPQYAGGRMR 89
++ ++++ E + + + +A Y+ + EID PL++ ++ G VP G R
Sbjct: 22 RKAAEMLKENCMRNVKLRKGGTVAGYIPRDGEIDVLPLMQFVKEEGNTVLVPVVQQGS-R 80
Query: 90 MLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLIIAPGVAFSRSGDRLGHGGGY 149
+L + + G+ ET +++ P VAF RS +RLG GGGY
Sbjct: 81 LLAFK----------RWNCYASGE--------ETIIPEVLFVPLVAFDRSLNRLGFGGGY 122
Query: 150 YDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQKVDEVI 193
YD I R + + VA+N Q+ ++P E DQK+D +I
Sbjct: 123 YDYTIAFFRRSFRCL--CIGVAYNAQLHHKIPVTEHDQKLDLII 164
>UniRef50_Q57BF7 Cluster: 5-formyltetrahydrofolate cyclo-ligase
family protein; n=15; Rhizobiales|Rep:
5-formyltetrahydrofolate cyclo-ligase family protein -
Brucella abortus
Length = 198
Score = 57.6 bits (133), Expect = 2e-07
Identities = 38/142 (26%), Positives = 64/142 (45%), Gaps = 8/142 (5%)
Query: 52 IALYMSTENEIDTAPLIKHIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQH 111
IA Y +EID PL+ +A+GA +P + D + +P G
Sbjct: 54 IAGYWPIRSEIDPRPLLSAFRAKGARLCLPVVLDAETIVFREFLPDAELVPT---GFGTM 110
Query: 112 GKDQARDDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVA 171
G D+ ++ +++ P F R G RLG+G G+YD+ + P ++ +A
Sbjct: 111 GPDE-HAPLVDPA---IMLMPLAGFDRLGHRLGYGAGHYDRALARF-AERGLQPLLIGMA 165
Query: 172 FNCQVVDEVPTNEQDQKVDEVI 193
F+CQ VD VP D + +++
Sbjct: 166 FDCQEVDYVPNEPHDIALHQIL 187
>UniRef50_O83692 Cluster: 5,10-methenyltetrahydrofolate synthetase,
putative; n=1; Treponema pallidum|Rep:
5,10-methenyltetrahydrofolate synthetase, putative -
Treponema pallidum
Length = 225
Score = 57.6 bits (133), Expect = 2e-07
Identities = 25/67 (37%), Positives = 40/67 (59%), Gaps = 1/67 (1%)
Query: 128 LIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLN-PETAPKIVAVAFNCQVVDEVPTNEQD 186
LI+ P +AFS +G RLG GGG+YD+F+ + P + + + F+CQ++ +P D
Sbjct: 139 LIVVPALAFSTNGARLGRGGGHYDRFLARIAATIPAGSYYTLGLCFDCQIMAVIPQEAHD 198
Query: 187 QKVDEVI 193
Q V V+
Sbjct: 199 QSVHAVL 205
>UniRef50_A6PRD6 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Victivallis vadensis ATCC BAA-548|Rep:
5-formyltetrahydrofolate cyclo-ligase - Victivallis
vadensis ATCC BAA-548
Length = 195
Score = 57.6 bits (133), Expect = 2e-07
Identities = 47/189 (24%), Positives = 86/189 (45%), Gaps = 14/189 (7%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 69
K LR A A+ E++ + + + Y+ S +A+Y + E D L
Sbjct: 7 KRELRERFLALRRAIAPAERREKDAAICRNIRALECYRRSECVAIYATDGEEPDLFGLWG 66
Query: 70 HIQARGAAAFVPQYAGGRMRMLHLETGD-EQTMPKTKHGISQHGKDQARDDALETGGLDL 128
+ F+P+Y R +E D E+ + K+G+ + + A A E +L
Sbjct: 67 EKRF-----FLPRYRADLKRYELVEVADRERELVAGKYGLLEPRPELAAA-APEFAAREL 120
Query: 129 I-IAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQ 187
+ + P VA +++G RLG GGG+YD+ + + P ++ V + CQ+ + +P D+
Sbjct: 121 LFLTPAVACTKAGVRLGRGGGFYDRMLAG-AVRP-----VIGVIYCCQLAEALPVEAHDR 174
Query: 188 KVDEVIFAE 196
V+ V+ E
Sbjct: 175 PVEVVVTEE 183
>UniRef50_Q2FMV3 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Methanospirillum hungatei JF-1|Rep:
5-formyltetrahydrofolate cyclo-ligase - Methanospirillum
hungatei (strain JF-1 / DSM 864)
Length = 193
Score = 57.6 bits (133), Expect = 2e-07
Identities = 41/144 (28%), Positives = 70/144 (48%), Gaps = 12/144 (8%)
Query: 52 IALYMSTENEIDTAPLIKHIQARGAAAFVP--QYAGGRMRMLHLETGDEQTMPKTKHGIS 109
+ +Y + E E++TA I H+ + VP + +R+ ++ T D P T H
Sbjct: 45 VLVYCAKEPEVETAWFIDHLLHQERKVIVPIIEEEDIGLRLSYINTRDV-LKPSTFHVPE 103
Query: 110 QHGKDQARDDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVA 169
G + D T I P + F RSG R+G+G GYYD+F++ +P K +
Sbjct: 104 PVGCELPADPHHVT----CAIIPMLGFDRSGGRIGYGAGYYDRFLSE---HPHI--KRIG 154
Query: 170 VAFNCQVVDEVPTNEQDQKVDEVI 193
VA++ Q V +P + D ++D ++
Sbjct: 155 VAYSVQEVPTIPVQDHDIRMDIIV 178
>UniRef50_Q9A3F9 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=2; Caulobacter|Rep: 5-formyltetrahydrofolate
cyclo-ligase - Caulobacter crescentus (Caulobacter
vibrioides)
Length = 214
Score = 57.2 bits (132), Expect = 2e-07
Identities = 41/144 (28%), Positives = 68/144 (47%), Gaps = 13/144 (9%)
Query: 53 ALYMSTENEIDTAPLIKHIQARGAAAFVPQYA---GGRMRMLHLETGDEQTMPKTKHGIS 109
ALY +EI L + + G +P+ GG+M G Q + + K G+
Sbjct: 68 ALYHGLGSEISPLILAEQMAEAGWTLALPKVVNPDGGKMIFRRWTPG--QPLKRDKIGLL 125
Query: 110 QHGKDQARDDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVA 169
G++Q DL++ P +AF R G RLG GGGYYD+ + LR ++
Sbjct: 126 APGREQPMIVP------DLVVTPLLAFQRDGVRLGQGGGYYDRALAFLRSRRPVF--VLG 177
Query: 170 VAFNCQVVDEVPTNEQDQKVDEVI 193
+A++ Q + +P DQ++D ++
Sbjct: 178 LAYSGQQAENLPHEAHDQRLDAIL 201
>UniRef50_Q7NBA0 Cluster: Putative uncharacterized protein; n=1;
Mycoplasma gallisepticum|Rep: Putative uncharacterized
protein - Mycoplasma gallisepticum
Length = 186
Score = 56.8 bits (131), Expect = 3e-07
Identities = 45/188 (23%), Positives = 84/188 (44%), Gaps = 11/188 (5%)
Query: 6 PNPAKALLRNEIAAKIAALTNEEKKR-QSQIVYEKVINHSWYKSSSRIALYMSTENEIDT 64
P +K ++R ++ + KK+ Q + + V K +I ++ S E DT
Sbjct: 2 PMQSKQIVRKQLIELAKQFASTPKKQIVDQQLTKLVYQFIKTKDYQKIGVFSSLFYEYDT 61
Query: 65 APLIKHIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETG 124
+ LI + ++P+ M ++ D K+ I Q ++ L
Sbjct: 62 SELINLLLEEDYQIYLPRVDNNEMNFYQIKQLDFSF--DLKYQIKQ----PLVNEQLLNN 115
Query: 125 GLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNE 184
LDL I P V ++ + RLGHG GYYD+F NL+ + ++VA++ + ++ +
Sbjct: 116 HLDLFIVPLVGYNSNQLRLGHGKGYYDRFFNNLKYSNYK----ISVAYDFMLNNQFQAQD 171
Query: 185 QDQKVDEV 192
D K+D++
Sbjct: 172 HDVKIDKI 179
>UniRef50_Q9F7S8 Cluster: Predicted 5-formyltetrahydrofolate
cyclo-ligase; n=1; uncultured marine gamma
proteobacterium EBAC31A08|Rep: Predicted
5-formyltetrahydrofolate cyclo-ligase -
Gamma-proteobacterium EBAC31A08
Length = 191
Score = 56.8 bits (131), Expect = 3e-07
Identities = 48/189 (25%), Positives = 86/189 (45%), Gaps = 11/189 (5%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 69
K +R + + ++++ K S ++ E V+ IALY NE++T LI+
Sbjct: 3 KNKIRKSLFEQGQSISDLSKSNISFLIQENVLEKINTHEMQNIALYFPFRNEVNTNLLIQ 62
Query: 70 HIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHG-KDQARDDALETGGLDL 128
++P+ M +L DEQ I+Q G K+ +D + +DL
Sbjct: 63 AFTKLKKNIYIPKVIDDEMMAFNLL--DEQP----NFFINQFGIKEVKSEDYVNINEIDL 116
Query: 129 IIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETA-PKIVAVAFNCQVVDEVPTNEQDQ 187
+ P +G RLG+G GY+D+ I + +N E + P +V + + Q+ + + D
Sbjct: 117 MFIPMTGVDLNGYRLGYGSGYFDRIIGS--INEEVSRPLLVGLCYQYQICNMHFGEKHDL 174
Query: 188 KVDEVIFAE 196
K D +F+E
Sbjct: 175 KYD-YVFSE 182
>UniRef50_A4CIN4 Cluster: Putative uncharacterized protein; n=1;
Robiginitalea biformata HTCC2501|Rep: Putative
uncharacterized protein - Robiginitalea biformata
HTCC2501
Length = 186
Score = 56.8 bits (131), Expect = 3e-07
Identities = 38/129 (29%), Positives = 66/129 (51%), Gaps = 10/129 (7%)
Query: 33 SQIVYEKVINHSWYKSSSRIALYMS--TENEIDTAPLIKHIQARGAAAFVPQYAGGRMRM 90
S+ + E+V H +R L++ ++ EIDTA L ++ RG +P+ G + +
Sbjct: 26 SKAIAERVF-HLPVSGKTRFHLFLPIRSKKEIDTAYLQAELRKRGKEIVIPRVVG-KGEL 83
Query: 91 LHLETGDEQTMPKTKHGISQ-HGKDQARDDALETGGLDLIIAPGVAFSRSGDRLGHGGGY 149
H T E + GI + G ++ ++L D++ P +AF G R+G+GGGY
Sbjct: 84 KHYLTTPETRFITSPWGIPEPEGAEEVPPESL-----DVVFIPLLAFDAGGHRVGYGGGY 138
Query: 150 YDKFITNLR 158
YD+F+ + R
Sbjct: 139 YDRFLQHCR 147
>UniRef50_UPI0001553191 Cluster: PREDICTED: hypothetical protein;
n=1; Mus musculus|Rep: PREDICTED: hypothetical protein
- Mus musculus
Length = 86
Score = 56.4 bits (130), Expect = 4e-07
Identities = 25/64 (39%), Positives = 46/64 (71%)
Query: 1 MSPIKPNPAKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTEN 60
M+ + N AK LR E+ ++ AL+ EE+ RQS ++ +KVI H+ Y++S RI++++S ++
Sbjct: 1 MAAVTVNSAKRGLRAELKQRLRALSAEERLRQSLLLTQKVIAHNQYQNSKRISIFLSMQD 60
Query: 61 EIDT 64
E++T
Sbjct: 61 EVET 64
>UniRef50_Q6N1F2 Cluster: Antifreeze protein, type
I:5-formyltetrahydrofolate cyclo-ligase; n=10;
Bradyrhizobiaceae|Rep: Antifreeze protein, type
I:5-formyltetrahydrofolate cyclo-ligase -
Rhodopseudomonas palustris
Length = 197
Score = 56.4 bits (130), Expect = 4e-07
Identities = 44/188 (23%), Positives = 79/188 (42%), Gaps = 9/188 (4%)
Query: 6 PNPAKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTA 65
P+ AK LR A+ +AL+ ++ + + + + + +A Y E+D
Sbjct: 8 PSDAKTALRAAALARRSALSQGDRSAAAAAIAARGLPVP-LPDGAIVAGYAPIRGELDPL 66
Query: 66 PLIKHIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGG 125
PL+ + A GA +P ++ + +P++ GI + D
Sbjct: 67 PLMHTLAAHGARLALPVVTRQGTPLVFRAWREGDALPRSALGIREPSSDAPEVTP----- 121
Query: 126 LDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQ 185
D+++ P AF SG R+G+G G+YD + LR + +AF Q + VP
Sbjct: 122 -DIVLVPLAAFDASGHRIGYGAGHYDCTLEYLRARGLVV--AIGLAFAMQQIPAVPAAAH 178
Query: 186 DQKVDEVI 193
D +D V+
Sbjct: 179 DVVLDYVL 186
>UniRef50_O68985 Cluster: Putative uncharacterized protein; n=1;
Chlorobaculum tepidum|Rep: Putative uncharacterized
protein - Chlorobium tepidum
Length = 199
Score = 56.4 bits (130), Expect = 4e-07
Identities = 45/191 (23%), Positives = 85/191 (44%), Gaps = 17/191 (8%)
Query: 9 AKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTEN--EIDTAP 66
+K LR + A+ A+T E S+ + + + ++R+ Y+S E+ E T
Sbjct: 7 SKPELRKRLLARRRAMTLERWLSDSEKIQAHAASLPKLREAARVHCYVSMEHDREARTLE 66
Query: 67 LIKHIQARGAAAFVPQYAGGRMRMLHLETGDE----QTMPKTKHGISQHGKDQARDDALE 122
L++ + G A ++P G M+ + + + P T + G+++
Sbjct: 67 LLEKLALEGKAVYMPYIEQGIMKTSIYHSAQKFRISVSAPPTPEPLVLSGEER------- 119
Query: 123 TGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPT 182
+++ P F R G R+G G G+YD+F + L P + +AF+ Q V VP
Sbjct: 120 ---FEVVFVPLTGFDRRGGRIGFGKGWYDRFFSRLS-GHGIHPVKIGLAFSFQEVPSVPC 175
Query: 183 NEQDQKVDEVI 193
+ D+ +D V+
Sbjct: 176 DPWDEPLDMVV 186
>UniRef50_Q1NDJ9 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Sphingomonas sp. SKA58|Rep:
5-formyltetrahydrofolate cyclo-ligase - Sphingomonas sp.
SKA58
Length = 196
Score = 56.4 bits (130), Expect = 4e-07
Identities = 47/147 (31%), Positives = 70/147 (47%), Gaps = 21/147 (14%)
Query: 52 IALYMSTENEIDTAPLIKHIQARGAAAFVPQYAG--GRMRMLHLETGDEQTMPKTKHGIS 109
+ALYM ++E L ++A G A +P+ G M + D+ +P
Sbjct: 55 VALYMGLDDEAPAQRLAPQLKAMGKAIALPRVIDRLGSMEFIAWNA-DDVLVPGLYR--- 110
Query: 110 QHGKDQARDDALETGGL---DLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPK 166
H D TGG+ D+I+ P VAF RS +RLG GGGYYD+ + PE
Sbjct: 111 THHPDP-------TGGVVSPDVIVTPLVAFDRSMNRLGQGGGYYDRALARF---PEALR- 159
Query: 167 IVAVAFNCQVVDEVPTNEQDQKVDEVI 193
+ VA++ Q +D VP + D +D V+
Sbjct: 160 -IGVAWSAQELDAVPADPWDLPLDMVL 185
>UniRef50_UPI0000384628 Cluster: COG0212: 5-formyltetrahydrofolate
cyclo-ligase; n=1; Magnetospirillum magnetotacticum
MS-1|Rep: COG0212: 5-formyltetrahydrofolate cyclo-ligase
- Magnetospirillum magnetotacticum MS-1
Length = 193
Score = 56.0 bits (129), Expect = 6e-07
Identities = 43/143 (30%), Positives = 69/143 (48%), Gaps = 13/143 (9%)
Query: 52 IALYMSTENEIDTAPLIKHIQARGAAAFVPQYAGGRMRMLHLETGDE-QTMPKTKHGISQ 110
+A Y + E+D PL++ + A G +P ETG + P T + +
Sbjct: 50 VAGYWPLKGEMDPLPLMEALAAEGHLLALPAVT---------ETGGTLEFRPWTPGEVLE 100
Query: 111 HGKDQARDDALETGGL-DLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVA 169
G R + + + ++ P +AF R G RLG+GGGYYD+ +++LR A +
Sbjct: 101 PGPHGTRHPSAASPIVPQALLVPLLAFDRRGFRLGYGGGYYDRTLSDLR--RRGAVPAIG 158
Query: 170 VAFNCQVVDEVPTNEQDQKVDEV 192
+AF Q V+ VPT+ D +D V
Sbjct: 159 LAFAAQEVERVPTDPWDIALDLV 181
>UniRef50_Q7NMK6 Cluster: Glr0759 protein; n=1; Gloeobacter
violaceus|Rep: Glr0759 protein - Gloeobacter violaceus
Length = 184
Score = 56.0 bits (129), Expect = 6e-07
Identities = 50/185 (27%), Positives = 84/185 (45%), Gaps = 19/185 (10%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIAL-YMSTENEIDTAPLI 68
KA LR + + AL+ E +R S+ + + +S+ R L Y+ NE D PL
Sbjct: 3 KADLRVQCLGRRRALSPEACERMSERIRAYLSGR--LESTDRCILAYLPFRNEPDLRPLF 60
Query: 69 KHIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDL 128
A VP+ AG + E G + G + + +A++ G
Sbjct: 61 ----ADSRTWAVPRVAGTELTWHRYEPG------RVGRGAMGPPEPEPDCEAVDPAGAAW 110
Query: 129 IIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQK 188
++ P VA R G R+G+GGGYYD+F+ L +AV ++ V ++VPT+ D+
Sbjct: 111 VLVPVVACDRRGYRIGYGGGYYDRFLARYAL------PAIAVGYSEFVYEQVPTDPWDRP 164
Query: 189 VDEVI 193
+ ++
Sbjct: 165 MGGIV 169
>UniRef50_Q31NN9 Cluster: Putative uncharacterized protein; n=2;
Synechococcus elongatus|Rep: Putative uncharacterized
protein - Synechococcus sp. (strain PCC 7942) (Anacystis
nidulans R2)
Length = 189
Score = 56.0 bits (129), Expect = 6e-07
Identities = 52/179 (29%), Positives = 88/179 (49%), Gaps = 16/179 (8%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 69
KA LR ++ A+ +L+ E+++ SQ + + S ++ ++ + Y E D L+
Sbjct: 9 KASLRRQLLAERRSLSVVERQQYSQAIAVHLQASSLFQRATTVLSYWPLGAEPDLRSLL- 67
Query: 70 HIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLI 129
+Q + A +P+ R+ + EQ + K G+ D E +DL+
Sbjct: 68 -LQPKQWA--LPRCQNQRLYAHCYQF--EQPLAKDCAGVLAPLADSLTVSPAE---IDLL 119
Query: 130 IAPGVAFSRSGDRLGHGGGYYDKFITNLRLNP--ETAPKIVAVAFNCQVVDEVPTNEQD 186
I P VA + G RLG+GGGYYD+ LR +P + P IV VA+ Q++ E+P + D
Sbjct: 120 IVPAVAVDKEGYRLGYGGGYYDR----LRADPAWRSIPAIV-VAYAAQIMSELPHDPWD 173
>UniRef50_Q0EWY4 Cluster: 5-formyltetrahydrofolate cyclo-ligase
family protein; n=1; Mariprofundus ferrooxydans
PV-1|Rep: 5-formyltetrahydrofolate cyclo-ligase family
protein - Mariprofundus ferrooxydans PV-1
Length = 190
Score = 56.0 bits (129), Expect = 6e-07
Identities = 46/186 (24%), Positives = 81/186 (43%), Gaps = 14/186 (7%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 69
K +LR+ + L+ E++ S+ + ++ + Y S NE+DT PL +
Sbjct: 6 KNVLRSSALSARRELSPEQRSAYSRTICLRLHEILAAAQPDCLLAYRSLPNEVDTTPLFQ 65
Query: 70 HIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDAL--ETGGLD 127
+ YA H+E + T G D+ ++ L G
Sbjct: 66 DTATQ-------LYAPVTHHHEHMEW--RKICRDTVWHAGVFGVDEPQEGPLWSAASGHT 116
Query: 128 LIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQ 187
+++ P VAF + G+RLG G G +D ++ R + +++ +AF+CQ V EVP D
Sbjct: 117 ILVCPLVAFDQRGNRLGMGKGCFDFWLAQYR---SSIDQVIGLAFSCQQVAEVPAERHDM 173
Query: 188 KVDEVI 193
+D +I
Sbjct: 174 PMDFII 179
>UniRef50_A6RBY2 Cluster: Predicted protein; n=1; Ajellomyces
capsulatus NAm1|Rep: Predicted protein - Ajellomyces
capsulatus NAm1
Length = 262
Score = 56.0 bits (129), Expect = 6e-07
Identities = 32/85 (37%), Positives = 46/85 (54%), Gaps = 13/85 (15%)
Query: 122 ETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETA----------PKIVAVA 171
E+ GLDL++ PG+AF RLGHG GYYD FI L+ N + P +VA+A
Sbjct: 163 ESSGLDLVVMPGLAFDEQLQRLGHGKGYYDHFINRLKGNRQNGGEENKAGMRRPHLVALA 222
Query: 172 FNCQVV---DEVPTNEQDQKVDEVI 193
Q++ ++P + D VD +I
Sbjct: 223 LTEQLLPSGKKIPVADHDCSVDSLI 247
>UniRef50_Q11X92 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Cytophaga hutchinsonii ATCC 33406|Rep:
5-formyltetrahydrofolate cyclo-ligase - Cytophaga
hutchinsonii (strain ATCC 33406 / NCIMB 9469)
Length = 193
Score = 55.6 bits (128), Expect = 7e-07
Identities = 43/149 (28%), Positives = 74/149 (49%), Gaps = 8/149 (5%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTEN--EIDTAPL 67
K +R + AK L+ + K++S+ + E I +K+ I +++S E+DT+ L
Sbjct: 3 KDAIRKQYIAKRNGLSETQVKQKSKAISETFIASEIWKTCRVIHIFISIPGKAEVDTSDL 62
Query: 68 IK--HIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGG 125
I + Q A + +LH E T K I + + A ++ ET
Sbjct: 63 IDFFYTQHPEIKLCTSILAENNIDLLHTHITPETTYLPNKWNIPEPVERNAVNE--ET-- 118
Query: 126 LDLIIAPGVAFSRSGDRLGHGGGYYDKFI 154
+DLI+ P VAF +G+R+G+G G+YD+F+
Sbjct: 119 IDLILLPLVAFDATGNRVGYGKGFYDRFL 147
>UniRef50_A3K0D8 Cluster: 5-formyltetrahydrofolate cyclo-ligase
family protein; n=1; Sagittula stellata E-37|Rep:
5-formyltetrahydrofolate cyclo-ligase family protein -
Sagittula stellata E-37
Length = 136
Score = 55.6 bits (128), Expect = 7e-07
Identities = 26/67 (38%), Positives = 42/67 (62%), Gaps = 2/67 (2%)
Query: 127 DLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQD 186
+++I P VAFSRSG RLG+GGG+YD+ + +R T + AF Q + ++P + D
Sbjct: 64 EILIVPLVAFSRSGGRLGYGGGFYDRTLERMRAKRPTL--AIGFAFAGQEMVDLPLEDTD 121
Query: 187 QKVDEVI 193
Q +D ++
Sbjct: 122 QPLDLIV 128
>UniRef50_P73038 Cluster: Sll1643 protein; n=1; Synechocystis sp.
PCC 6803|Rep: Sll1643 protein - Synechocystis sp.
(strain PCC 6803)
Length = 188
Score = 55.2 bits (127), Expect = 1e-06
Identities = 47/184 (25%), Positives = 86/184 (46%), Gaps = 9/184 (4%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 69
KA LR ++ + L+ + ++QS + ++ S ++ +SRI Y ST+ E D PL
Sbjct: 3 KAQLRAQLLQERRQLSEAQWQQQSLELCAQLQQWSVFQQASRICAYCSTQREADLQPLFD 62
Query: 70 HIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLI 129
+ + +P+ + + G Q + +GI DQ + T +DL+
Sbjct: 63 RL-GKAKVWVLPRCVQKSLVWHPWQWG--QPLTTGAYGIKVPA-DQTEIWSPNT--VDLL 116
Query: 130 IAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQKV 189
+ P +A R G RLG+GGGYYD+ + PK V + F + +++P + D +
Sbjct: 117 LVPCLAGDRQGYRLGYGGGYYDRLFADPLW--RAVPK-VGILFEAGLREKLPHDPWDMPL 173
Query: 190 DEVI 193
++
Sbjct: 174 QTLV 177
>UniRef50_Q1GFD0 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=20; Rhodobacterales|Rep: 5-formyltetrahydrofolate
cyclo-ligase - Silicibacter sp. (strain TM1040)
Length = 195
Score = 55.2 bits (127), Expect = 1e-06
Identities = 40/142 (28%), Positives = 64/142 (45%), Gaps = 10/142 (7%)
Query: 52 IALYMSTENEIDTAPLIKHIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQH 111
+A YM EID ++ A G VP G + + E + G
Sbjct: 53 LAGYMPIRTEIDPLGVMAEAAAHGPVG-VPVIQGAGLPLKFSRWQPEGALRDGPFG---- 107
Query: 112 GKDQARDDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVA 171
K DD + +++I P VAF +G+RLG+GGG+YD+ + RL + A + A
Sbjct: 108 AKVPEVDDYFDP---EILIVPLVAFDAAGNRLGYGGGFYDRTLD--RLRAQRATLAIGFA 162
Query: 172 FNCQVVDEVPTNEQDQKVDEVI 193
F+ Q + +P DQ +D ++
Sbjct: 163 FDAQEAEGLPLEPTDQPLDMIV 184
>UniRef50_A1A037 Cluster: Putative uncharacterized protein; n=2;
Bifidobacterium adolescentis|Rep: Putative
uncharacterized protein - Bifidobacterium adolescentis
(strain ATCC 15703 / DSM 20083)
Length = 206
Score = 55.2 bits (127), Expect = 1e-06
Identities = 46/173 (26%), Positives = 78/173 (45%), Gaps = 10/173 (5%)
Query: 27 EEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQARGAAAFVPQY-AG 85
++++ +++ E + S + S +A + S +EI PL++ + VP+ AG
Sbjct: 28 DQRREAGRLLAEHALEASLIRPRSTVAAFASMGSEISMMPLLEAMFDTDCRVLVPRLGAG 87
Query: 86 GRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALE----TGGLDLIIAPGVAFSRSGD 141
+ L D+ + G + Q ++A E +LII P A G
Sbjct: 88 MEVGWSELNGLDDLRDQRNADGSINTHRPQEPENAAEGPEVLTSAELIIVPAFAVDEHGF 147
Query: 142 RLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDE-VPTNEQDQKVDEVI 193
RLG GGG+YD+ + + TA ++VAV + + DE VP D VD V+
Sbjct: 148 RLGRGGGWYDRALEH---RSSTA-RVVAVCWPWEPTDETVPHEPHDIPVDGVL 196
>UniRef50_Q8DK86 Cluster: Tll0980 protein; n=1; Synechococcus
elongatus|Rep: Tll0980 protein - Synechococcus elongatus
(Thermosynechococcus elongatus)
Length = 190
Score = 54.8 bits (126), Expect = 1e-06
Identities = 41/169 (24%), Positives = 77/169 (45%), Gaps = 11/169 (6%)
Query: 24 LTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQARGAAAFVPQY 83
L++ E + +S+ + +++ +H ++ ++ + Y+ E D L + G V
Sbjct: 23 LSDREWQDRSRRICQQLFDHPQFQQATTVLTYVPHRREPDLRSLWSVPKQWGLPRVV--- 79
Query: 84 AGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLIIAPGVAFSRSGDRL 143
GR H G E T+ + +G+ Q D ++ G+DL + P VA R G RL
Sbjct: 80 --GRNLQWHCFDGKEDTLQQGPYGLWQPSPDAP---PIDPAGVDLCLIPAVACDRRGYRL 134
Query: 144 GHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQKVDEV 192
G+G G++D+ + IV F VV+E+P + D ++ +
Sbjct: 135 GYGAGFFDRLFAHPDWQHVCRWGIV---FEAAVVEELPHDPWDLRLQAI 180
>UniRef50_Q0F944 Cluster: Putative 5-formyltetrahydrofolate
cyclo-ligase; n=1; alpha proteobacterium HTCC2255|Rep:
Putative 5-formyltetrahydrofolate cyclo-ligase - alpha
proteobacterium HTCC2255
Length = 188
Score = 54.8 bits (126), Expect = 1e-06
Identities = 45/143 (31%), Positives = 60/143 (41%), Gaps = 11/143 (7%)
Query: 52 IALYMSTENEIDTAPLIKHIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQH 111
IA YM EI P + I RG VP + E E M G
Sbjct: 48 IAAYMPIRTEISPLPAMTKISKRGHKICVPVVVKDGTPLKFFEWTPETKMVSGAFGALIP 107
Query: 112 GKDQARDDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNL-RLNPETAPKIVAV 170
K D+II P AF +G RLG+GGG+YD+ + +L TA V
Sbjct: 108 EKSNRLIP-------DIIITPLAAFDMNGYRLGYGGGFYDRSFEEITKLKEITA---VGF 157
Query: 171 AFNCQVVDEVPTNEQDQKVDEVI 193
A++ Q V VP+ D K+D++I
Sbjct: 158 AYSSQEVLAVPSEPTDYKLDQII 180
>UniRef50_Q0AVU2 Cluster: 5-formyltetrahydrofolate cyclo-ligase
family protein; n=1; Syntrophomonas wolfei subsp. wolfei
str. Goettingen|Rep: 5-formyltetrahydrofolate
cyclo-ligase family protein - Syntrophomonas wolfei
subsp. wolfei (strain Goettingen)
Length = 194
Score = 54.8 bits (126), Expect = 1e-06
Identities = 39/168 (23%), Positives = 76/168 (45%), Gaps = 12/168 (7%)
Query: 13 LRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQ 72
LR + +T E + S+ + ++ + + I + S +NE+D P ++ +
Sbjct: 11 LRKRMLEARNVMTASEAEELSRRIGCRLEELESLRQAKSIMGFASVKNEVDLRPFMEQQR 70
Query: 73 ARGAAAFVPQY-AGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLIIA 131
+G F+P+ + G+M + G QT G + A+ +D+++
Sbjct: 71 GQGKRIFLPRVESAGKMVAVEFR-GWGQTAS------GPFGIREPLGPAVPAAEIDVVLV 123
Query: 132 PGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDE 179
PG+ F G RLG+G GYYD+F+ + E + V + Q++D+
Sbjct: 124 PGLVFDTRGYRLGYGKGYYDRFLAGM----EERVFLCGVCYEFQIIDD 167
>UniRef50_A3V9L4 Cluster: 5-formyltetrahydrofolate cyclo-ligase
family protein; n=1; Rhodobacterales bacterium
HTCC2654|Rep: 5-formyltetrahydrofolate cyclo-ligase
family protein - Rhodobacterales bacterium HTCC2654
Length = 182
Score = 54.8 bits (126), Expect = 1e-06
Identities = 27/67 (40%), Positives = 42/67 (62%), Gaps = 4/67 (5%)
Query: 128 LIIAPGVAFSRSGDRLGHGGGYYDKFITNLR-LNPETAPKIVAVAFNCQVVDEVPTNEQD 186
++I P VAF R+G+RLG+GGG+YD+ + LR L P A + AF Q + ++P D
Sbjct: 110 VLIVPLVAFDRAGNRLGYGGGFYDRTLAALRALRPTLA---IGYAFAAQELPDLPLEPTD 166
Query: 187 QKVDEVI 193
Q +D ++
Sbjct: 167 QPLDAIV 173
>UniRef50_A0JYX4 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=2; Arthrobacter|Rep: 5-formyltetrahydrofolate
cyclo-ligase - Arthrobacter sp. (strain FB24)
Length = 198
Score = 54.8 bits (126), Expect = 1e-06
Identities = 40/142 (28%), Positives = 62/142 (43%), Gaps = 5/142 (3%)
Query: 50 SRIALYMSTENEIDTAPLIKHIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGIS 109
S A+Y+ E T PLI + G +P R T + + + I
Sbjct: 47 STFAVYLGVGFEPPTLPLITALHGTGHRVLLPVCGPDRALSWVYWTPATEFVRSSYAPIE 106
Query: 110 QHGKDQARDDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVA 169
+ +Q +A++ G+ I P A SG+R+G GGGYYDKF+ L P A
Sbjct: 107 EPVGEQHGSEAMD--GVAGIFVPATAVDLSGNRIGQGGGYYDKFLAGLEAAGRPVP-AAA 163
Query: 170 VAFNCQVV--DEVPTNEQDQKV 189
V F+ +++ +P D+KV
Sbjct: 164 VVFDGEILPAGTIPAESFDRKV 185
>UniRef50_Q0RC09 Cluster: Putative ligase; n=1; Frankia alni
ACN14a|Rep: Putative ligase - Frankia alni (strain
ACN14a)
Length = 262
Score = 54.4 bits (125), Expect = 2e-06
Identities = 38/142 (26%), Positives = 65/142 (45%), Gaps = 10/142 (7%)
Query: 52 IALYMSTENEIDTAPLIKHIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQH 111
+A Y+ E D A L+ + ARG +P L+ + G
Sbjct: 108 VAAYVGLPGEPDLADLLARLLARGTRVLLPVVRAD------LDLDFREYAGTLIPGALGT 161
Query: 112 GKDQARDDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVA 171
+ A + + D +I P +A R+G RLG GGG YD+ + R+ P+ ++AV
Sbjct: 162 REPPAAAPSGDLSAADAVIIPALAVDRAGRRLGRGGGSYDRALR--RVAPDV--PVIAVL 217
Query: 172 FNCQVVDEVPTNEQDQKVDEVI 193
++ +++D VPT E D+ V ++
Sbjct: 218 YDQELLDLVPTEEHDRSVKIIV 239
>UniRef50_A1SES9 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=3; Actinomycetales|Rep: 5-formyltetrahydrofolate
cyclo-ligase - Nocardioides sp. (strain BAA-499 / JS614)
Length = 194
Score = 54.4 bits (125), Expect = 2e-06
Identities = 41/183 (22%), Positives = 85/183 (46%), Gaps = 7/183 (3%)
Query: 7 NPAKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAP 66
+PAK+ +R+ + E ++ + E ++ + ++ +A Y+S +E + P
Sbjct: 6 SPAKSAVRDRLLTTRHRRPLAEVGVAARAIAEHLLALPEVRRAATVAAYVSVGSEPGSGP 65
Query: 67 LIKHIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGL 126
L+ ++A G +P G + +P + G+ + ++ +A+ T
Sbjct: 66 LLAGLRAAGKRVLLPVVLPDLDLDWAAYDGPDHLVP-ARRGLLEPDAERLGPEAIGTA-- 122
Query: 127 DLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQD 186
D+++ PG+A S SG RLG GGG YD+ + + + T + ++ +V +VP D
Sbjct: 123 DVVLTPGLAVSPSGVRLGRGGGCYDRALGRVPVGTFTC----VLLYDGEVGLDVPVEPHD 178
Query: 187 QKV 189
+ V
Sbjct: 179 RPV 181
>UniRef50_A1FY99 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=12; Xanthomonadaceae|Rep: 5-formyltetrahydrofolate
cyclo-ligase - Stenotrophomonas maltophilia R551-3
Length = 197
Score = 54.4 bits (125), Expect = 2e-06
Identities = 46/186 (24%), Positives = 82/186 (44%), Gaps = 7/186 (3%)
Query: 7 NPAKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAP 66
+P +AL R+++ + L+ E+ ++ + + ++ + +A Y + + EI
Sbjct: 3 DPRQAL-RHDLRQRRRDLSAGERIAAAESLADALLALPFAPCEGAVAGYWALDGEIALHR 61
Query: 67 LIKHIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGL 126
+ G +P AG +R G Q + ++GI + D +D LE +
Sbjct: 62 WQLQLP-EGLTYCLPVLAGDVLRFAPWRPG--QPLTSNRYGIPE--PDVTVEDTLEPAQM 116
Query: 127 DLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQD 186
L++ P V F RLG GGG+YD+ R + P +V AF Q V+ +P D
Sbjct: 117 ALVVTPLVGFDTQCRRLGMGGGWYDRSFA-FRHDRPAPPWLVGAAFAVQQVESLPVASWD 175
Query: 187 QKVDEV 192
VD +
Sbjct: 176 VPVDAI 181
>UniRef50_Q2J5Q1 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=2; Frankia|Rep: 5-formyltetrahydrofolate cyclo-ligase
- Frankia sp. (strain CcI3)
Length = 259
Score = 54.0 bits (124), Expect = 2e-06
Identities = 40/142 (28%), Positives = 62/142 (43%), Gaps = 10/142 (7%)
Query: 52 IALYMSTENEIDTAPLIKHIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQH 111
+A Y+ E DTA L+ + ARG +P G T+ G +
Sbjct: 105 VAAYVGLPGEPDTAELLDRLLARGVRVLLPALRADLDLDFREHVG---TLVPGALGTREP 161
Query: 112 GKDQARDDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVA 171
R E D++I P +A R+G RLG GGG YD+ + R+ + ++AV
Sbjct: 162 PAAAPRGVLAEA---DVVIIPALAVDRTGRRLGRGGGSYDRVLA--RVGADV--PVIAVL 214
Query: 172 FNCQVVDEVPTNEQDQKVDEVI 193
+ +V+DE+P D V +I
Sbjct: 215 HDQEVLDEIPMESHDHNVKIII 236
>UniRef50_Q1NVQ1 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=2; delta proteobacterium MLMS-1|Rep:
5-formyltetrahydrofolate cyclo-ligase - delta
proteobacterium MLMS-1
Length = 199
Score = 54.0 bits (124), Expect = 2e-06
Identities = 49/188 (26%), Positives = 93/188 (49%), Gaps = 10/188 (5%)
Query: 12 LLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAP-LIKH 70
L +N++AA+ L+ ++ +S+ ++ + + + +Y+ +E++T P L +
Sbjct: 9 LRQNKLAAR-DRLSPARRQSKSRAIHAALGGLEAVARARWLLVYLHFRSEVETLPALAAN 67
Query: 71 IQAR-GAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLI 129
+ +R AA A ++R+ L + + GI + D A ++ LD++
Sbjct: 68 LPSRCQIAAPRTLVATKQLRLYQLADPRQPAVKPGYCGIPE--PDPAHCLPVDPRALDVV 125
Query: 130 IAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDE-VPTNEQDQK 188
+ PG F R G RLG+GGGYYD+F L + A +I +AF QV ++ + DQ
Sbjct: 126 LVPGSVFDRRGGRLGYGGGYYDRF---LAVEAPQAIRI-GLAFALQVQNQPLALALHDQP 181
Query: 189 VDEVIFAE 196
+D ++ E
Sbjct: 182 LDYLVTEE 189
>UniRef50_A4F7U0 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=3; Actinomycetales|Rep: 5-formyltetrahydrofolate
cyclo-ligase - Saccharopolyspora erythraea (strain NRRL
23338)
Length = 301
Score = 54.0 bits (124), Expect = 2e-06
Identities = 43/186 (23%), Positives = 81/186 (43%), Gaps = 11/186 (5%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 69
KA R ++ + A + ++ + E V+ + + + Y+ E + L+
Sbjct: 114 KAQWRRKLLDRRGATNGTTRSAEAAALGEAVLRWLDDRPGATVCAYVPVGGEPGSPELLD 173
Query: 70 HIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLI 129
++A+G +P TG + P +G+ + + +A+ G D +
Sbjct: 174 ELRAKGHRVLLPVVVRSSPLDWAAYTGPDSLEP-AGYGLLEPSGARLGPEAI--GEADAV 230
Query: 130 IAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAP--KIVAVAFNCQVVDEVPTNEQDQ 187
+ P +A R G RLG G GYYD+ + P AP +VAV + + V+E+P + D
Sbjct: 231 LVPALAVDRRGVRLGRGAGYYDRSL------PMAAPAAALVAVVRDEEFVEELPGEDHDV 284
Query: 188 KVDEVI 193
+V V+
Sbjct: 285 RVGAVL 290
>UniRef50_Q6SHV0 Cluster: 5-formyltetrahydrofolate cyclo-ligase
family protein; n=1; uncultured bacterium 311|Rep:
5-formyltetrahydrofolate cyclo-ligase family protein -
uncultured bacterium 311
Length = 192
Score = 53.6 bits (123), Expect = 3e-06
Identities = 40/145 (27%), Positives = 62/145 (42%), Gaps = 8/145 (5%)
Query: 51 RIALYMSTENEIDTAPLIKHIQARGAAAFVPQYAG--GRMRMLHLETGDEQTMPKTKHGI 108
++++Y+ NE+ T +I+ I F+P M E E + K K I
Sbjct: 45 KVSIYIPIHNEVPTKRIIQLIIGSNTKCFLPVINQDLNNKNMRFAEFNHETALVKNKFDI 104
Query: 109 SQHGKDQARDDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIV 168
S+ + LDL++ P VAF G RLG G GYYD ++N + P
Sbjct: 105 SEPISGTFEN----ASQLDLVVIPLVAFDNEGFRLGMGKGYYDFTFGTSKINRK--PLFW 158
Query: 169 AVAFNCQVVDEVPTNEQDQKVDEVI 193
++++ Q D E D K+ VI
Sbjct: 159 GLSYDFQKTDSCYPEEHDLKMQAVI 183
>UniRef50_Q15Q29 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Pseudoalteromonas atlantica T6c|Rep:
5-formyltetrahydrofolate cyclo-ligase -
Pseudoalteromonas atlantica (strain T6c / BAA-1087)
Length = 198
Score = 53.6 bits (123), Expect = 3e-06
Identities = 41/169 (24%), Positives = 75/169 (44%), Gaps = 8/169 (4%)
Query: 14 RNEIAAKIAALTNEEKKRQSQIVYEKVINH----SWYKSSSRIALYMSTENEIDTAPLIK 69
RN++ N + Q E+++ + Y+++ +A Y++ + EI PLI
Sbjct: 7 RNQLRRHFRQARNNLSQAQQTFASEQLLMQCSALTEYQNAHVVACYLAQDGEIALTPLIN 66
Query: 70 HIQARGAAAFVPQ-YAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDL 128
+G +P + + ++ + M + GI + + D + LD+
Sbjct: 67 DAWLKGKTVCLPVLHPFCKGHLVFVRYRQNSKMQTNRFGILEPKLNAC--DIVPIAKLDV 124
Query: 129 IIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVV 177
I P VAF + RLG GGG+YD+ + + + E +I VA +CQ V
Sbjct: 125 IFTPLVAFDDTAQRLGMGGGFYDRTLAPVTRH-EIPLQIYGVAHDCQKV 172
>UniRef50_Q8YMV1 Cluster: All4825 protein; n=8; Cyanobacteria|Rep:
All4825 protein - Anabaena sp. (strain PCC 7120)
Length = 193
Score = 53.2 bits (122), Expect = 4e-06
Identities = 45/187 (24%), Positives = 84/187 (44%), Gaps = 17/187 (9%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 69
K+ LR + +++ E + +S + + + + + S+ I Y S E D + L
Sbjct: 12 KSQLRRSLIKTRQSMSIGEWREKSDRISCLLQSSTLFTQSTTILAYFSFRQEPDLSSLFA 71
Query: 70 HIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDA--LETGGLD 127
H R P+ +R +PK I+ +G + A ++ +D
Sbjct: 72 HTHHRWG---FPRCVDQSLRW-------HSWIPKDSLNINAYGIKEPDPQAPTIDPEEVD 121
Query: 128 LIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPK-IVAVAFNCQVVDEVPTNEQD 186
LI+ P VA + G RLG+GGGYYD+ ++ +PE + K + + F+ + ++P D
Sbjct: 122 LILVPSVACNYQGYRLGYGGGYYDRLLS----SPEWSTKPSIGIVFDFAYLPQLPIENWD 177
Query: 187 QKVDEVI 193
Q + V+
Sbjct: 178 QPLQAVL 184
>UniRef50_A6EDM4 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Pedobacter sp. BAL39|Rep: 5-formyltetrahydrofolate
cyclo-ligase - Pedobacter sp. BAL39
Length = 191
Score = 53.2 bits (122), Expect = 4e-06
Identities = 54/191 (28%), Positives = 90/191 (47%), Gaps = 16/191 (8%)
Query: 10 KALLRNEIAAKIAALTNEEKKR-QSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLI 68
K+ +R EI + AL+ E + ++ + I +S I L + +NE DT +I
Sbjct: 3 KSEIRKEIMVRRTALSKAEMVEINASLLRQFSILDFTEINSIHIFLPIVEKNEPDTFLMI 62
Query: 69 KHIQARGAAA--FVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGL 126
++A VP+ M + ++ + + + I + K AL TG +
Sbjct: 63 DWLKAHQPQIKIIVPKADFDTALMTNHHYEGKEDLQENLYKILEPQKG-----ALHTGDV 117
Query: 127 DLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFN-CQVVDEVPTNEQ 185
D++I P +AF SG+R+G+G G+YD+F L P KI F+ V+D+V N
Sbjct: 118 DMVIIPLLAFDMSGNRVGYGKGFYDRF-----LQPMGTRKIGLSLFSELTVIDDV--NVH 170
Query: 186 DQKVDEVIFAE 196
D K+DE + E
Sbjct: 171 DVKLDECLTPE 181
>UniRef50_A6DB91 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Caminibacter mediatlanticus TB-2|Rep:
5-formyltetrahydrofolate cyclo-ligase - Caminibacter
mediatlanticus TB-2
Length = 203
Score = 53.2 bits (122), Expect = 4e-06
Identities = 48/171 (28%), Positives = 74/171 (43%), Gaps = 18/171 (10%)
Query: 27 EEKKRQSQIVYEKVINHSWY---KSSSRIALYMSTENEIDTAPLIKHIQARGAAAFVPQY 83
+E + ++ ++ K+I+ Y K I L++ ENE D PLIK ++ FVP
Sbjct: 16 KENLKINRYLFSKIISKELYNISKEYKNILLFIPLENEADIKPLIKKLRREKKNIFVPFM 75
Query: 84 AGGRMRMLHLETGDEQTMPKTKHGISQ-HGKDQARDDALETGGLDLIIAPGVAFSRSGDR 142
G +M+ + K K I + H K++ + +DL I P + R
Sbjct: 76 EGLSFKMVKYSL----PLKKKKFSIIEPHNKNKTLEK------IDLAIVPVLGVDSDFRR 125
Query: 143 LGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQKVDEVI 193
+G G G YD+F +L PKIV V ++E D K DE I
Sbjct: 126 IGFGKGMYDRFFESLGYK----PKIVFVQIRPCFSKIKVSDEYDIKADEYI 172
>UniRef50_A4TWG6 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=3; Alphaproteobacteria|Rep: 5-formyltetrahydrofolate
cyclo-ligase - Magnetospirillum gryphiswaldense
Length = 200
Score = 53.2 bits (122), Expect = 4e-06
Identities = 39/142 (27%), Positives = 62/142 (43%), Gaps = 8/142 (5%)
Query: 52 IALYMSTENEIDTAPLIKHIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQH 111
+A Y +EID PL++ + RG +P + + + + HG +
Sbjct: 56 VAGYWPMGDEIDPLPLLEALGGRGCTLALPVVSARGQPLTFRAWSMGEALEPGPHGTNH- 114
Query: 112 GKDQARDDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVA 171
A L +++ P +AF +G RLG+GGGYYD+ + LR + VA
Sbjct: 115 --PLAVAPMLIP---QVLLLPLLAFDAAGYRLGYGGGYYDRTLDQLRRQSHVT--AIGVA 167
Query: 172 FNCQVVDEVPTNEQDQKVDEVI 193
F Q V VP DQ +D ++
Sbjct: 168 FAAQRVGAVPRGPHDQTLDLIL 189
>UniRef50_A1URD6 Cluster: 5,10-methenyltetrahydrofolate synthetase;
n=3; Bartonella|Rep: 5,10-methenyltetrahydrofolate
synthetase - Bartonella bacilliformis (strain ATCC 35685
/ KC583)
Length = 212
Score = 53.2 bits (122), Expect = 4e-06
Identities = 38/145 (26%), Positives = 65/145 (44%), Gaps = 9/145 (6%)
Query: 52 IALYMSTENEIDTAPLIKHIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQH 111
+A Y +E+D P ++++ +RG +P M+ + + + H
Sbjct: 71 VAGYWPIRSELDPGPFLEYVVSRGGRLALPAVIDDET-MVFRAYSPHTPLERARF----H 125
Query: 112 GKDQARDDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVA 171
A+ T I+ P +AF R +RLG+G GYYD+ I L+ + +
Sbjct: 126 TMSPGASSAVVTP--TFILVPLLAFDRQYNRLGYGKGYYDRAIAALKAEGHCI-DLFGLG 182
Query: 172 FNCQVVDEVPTNEQDQKVDEVIFAE 196
F+CQ V+ +P+ E D V + IF E
Sbjct: 183 FSCQEVESIPSTEHD-LVLQGIFTE 206
>UniRef50_Q2JU73 Cluster: 5-formyltetrahydrofolate cyclo-ligase
family protein; n=2; Synechococcus|Rep:
5-formyltetrahydrofolate cyclo-ligase family protein -
Synechococcus sp. (strain JA-3-3Ab) (Cyanobacteria
bacteriumYellowstone A-Prime)
Length = 210
Score = 52.8 bits (121), Expect = 5e-06
Identities = 27/72 (37%), Positives = 40/72 (55%), Gaps = 2/72 (2%)
Query: 121 LETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEV 180
++ G DLI+ P +A R G RLG+GGGYYD+F+ L PK V C + +
Sbjct: 127 IDPGKADLILVPALACDRWGRRLGYGGGYYDRFLA--ALPDPGVPKWGIVPQACLLEQPL 184
Query: 181 PTNEQDQKVDEV 192
P + DQ++D +
Sbjct: 185 PQDPWDQRLDGI 196
>UniRef50_UPI00006CBD0D Cluster: 5-formyltetrahydrofolate
cyclo-ligase family protein; n=1; Tetrahymena
thermophila SB210|Rep: 5-formyltetrahydrofolate
cyclo-ligase family protein - Tetrahymena thermophila
SB210
Length = 186
Score = 52.4 bits (120), Expect = 7e-06
Identities = 41/186 (22%), Positives = 87/186 (46%), Gaps = 15/186 (8%)
Query: 9 AKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLI 68
+K LR+++ K A + + Q + + E V S + + ++EI+ +I
Sbjct: 7 SKITLRSQLKQKRADFVKSQTQSQLKQIEEDV--------SKNLQSFYPIQSEINCIEVI 58
Query: 69 KHIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDL 128
K++Q + A + ++ L+ + T+ I + +D+ + ++
Sbjct: 59 KNLQDQYTCALPVHFKNEELKPLYFR----EFKSDTQLIIGHYNIPIPSEDSPQVIP-NI 113
Query: 129 IIAPGVAFSR-SGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQ 187
I+ P + F + + R+G GGG++D+ I + N + K V + F CQ + ++P EQD+
Sbjct: 114 ILTPFLGFDKLTLQRIGFGGGHFDRTIKYFKEN-QIKLKFVGIGFQCQYIQDLPAEEQDE 172
Query: 188 KVDEVI 193
+D +I
Sbjct: 173 PLDCII 178
>UniRef50_Q82Y32 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=3; Nitrosomonadaceae|Rep: 5-formyltetrahydrofolate
cyclo-ligase - Nitrosomonas europaea
Length = 208
Score = 52.4 bits (120), Expect = 7e-06
Identities = 39/148 (26%), Positives = 64/148 (43%), Gaps = 11/148 (7%)
Query: 46 YKSSSRIALYMSTENEIDTAPLIKHIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTK 105
+ + RI Y + E D P + ++ RGA +P+ + +E E M K
Sbjct: 46 FLENQRIGFYWPHQGEYDPIPAMTFLRTRGATLALPEVISKDEPLRFIEWWPEAPMKKDI 105
Query: 106 HGISQHGKDQARDDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAP 165
+GI D R + D II P + F G RLG+G GY+D+ T ++P P
Sbjct: 106 YGIPF--PDNTRGITV-----DSIIIPLLGFDEQGYRLGYGSGYFDR--TLAAMSPR--P 154
Query: 166 KIVAVAFNCQVVDEVPTNEQDQKVDEVI 193
+ VAF + + + D +D ++
Sbjct: 155 LAIGVAFEILRLPTIHPQQHDIPMDYIV 182
>UniRef50_Q03B49 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Lactobacillus casei ATCC 334|Rep:
5-formyltetrahydrofolate cyclo-ligase - Lactobacillus
casei (strain ATCC 334)
Length = 186
Score = 52.4 bits (120), Expect = 7e-06
Identities = 40/152 (26%), Positives = 71/152 (46%), Gaps = 7/152 (4%)
Query: 8 PAKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPL 67
P+KA R ++ A + + ++ V W ++ S I + +S E+ T P+
Sbjct: 2 PSKAEFRPLQLKRLKAAQKATQAASAALLAALVQTPMWQRAHS-IGVTVSGPFEVPTEPI 60
Query: 68 IKHIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLD 127
I+ A ++P+ R +M+ L + + + GI + + D + D
Sbjct: 61 IQAAHDANKAVYLPRVMPKR-QMVFLPDPGKDKLITSAFGIPE---PPYQADQIHAAP-D 115
Query: 128 LIIAPGVAFSRSGD-RLGHGGGYYDKFITNLR 158
LI+ PG+ FS + R+G GGGYYD+F+T R
Sbjct: 116 LILVPGIGFSLADKYRIGFGGGYYDRFLTTYR 147
>UniRef50_Q6F1L6 Cluster: 5-formyltetrahydrofolate cyclo-ligase
family protein; n=1; Mesoplasma florum|Rep:
5-formyltetrahydrofolate cyclo-ligase family protein -
Mesoplasma florum (Acholeplasma florum)
Length = 215
Score = 52.0 bits (119), Expect = 9e-06
Identities = 45/185 (24%), Positives = 83/185 (44%), Gaps = 6/185 (3%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIK 69
K +R + + L+ K+ ++I+ KV ++ + + A+Y+STENE +T +I+
Sbjct: 4 KNQIREKFLKTRSFLSKSYKEEVNKIIERKVNHYIDRYNLEKYAIYLSTENEPNTLNIIE 63
Query: 70 HIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGG-LDL 128
+G +VP T E + + K + + ++ LE G ++
Sbjct: 64 TSLKKGIEVYVPLIIEDNKMEFKKITNLETDLEQNK--VLNILQPKSTCSTLENGNYINT 121
Query: 129 IIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQK 188
+ P VAF + +R+G G G+YD+++ N KI A + + +E D K
Sbjct: 122 MFIPLVAFDKQLNRVGMGKGFYDRWLNE---NDYIGYKIGLSASTQLSNESIDADEFDVK 178
Query: 189 VDEVI 193
D VI
Sbjct: 179 FDNVI 183
>UniRef50_Q6AAH0 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Propionibacterium acnes|Rep:
5-formyltetrahydrofolate cyclo-ligase -
Propionibacterium acnes
Length = 195
Score = 52.0 bits (119), Expect = 9e-06
Identities = 46/185 (24%), Positives = 80/185 (43%), Gaps = 7/185 (3%)
Query: 6 PNPAKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTA 65
P K LR A AAL + + + E ++ + + ++ALY+S +E DT
Sbjct: 3 PPSGKEELRRRCLAHRAALDHRTRMSRDDRRTEHAMSRLLW--AHKVALYLSRGDEPDTV 60
Query: 66 PLIKHIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARD-DALETG 124
L + G P G R LH + G+ Q + A A
Sbjct: 61 DLADTLIMMGKKVLAPVLTDGHGRSLHEPAWAWYDSKNIRTGLWQIPEPIAPILPASAID 120
Query: 125 GLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNE 184
+++++ + RSG R+G GGG+YD+ + + + P + AV + +++DEVP +
Sbjct: 121 QVEVVLCSALFVDRSGYRVGVGGGWYDRVLVH---RADDVP-VWAVVNDDEILDEVPHDP 176
Query: 185 QDQKV 189
D+ V
Sbjct: 177 WDEPV 181
>UniRef50_Q5FUD7 Cluster: 5-Formyltetrahydrofolate cyclo-ligase;
n=1; Gluconobacter oxydans|Rep: 5-Formyltetrahydrofolate
cyclo-ligase - Gluconobacter oxydans (Gluconobacter
suboxydans)
Length = 195
Score = 52.0 bits (119), Expect = 9e-06
Identities = 43/182 (23%), Positives = 72/182 (39%), Gaps = 14/182 (7%)
Query: 12 LLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHI 71
LL+ ++ K+A L + + ++ + + RIA E+D PL +
Sbjct: 11 LLKKDLRLKMAQLRQAASPDDEAALRKFLLKEILARPAHRIAAVWPLAGEVDLRPLCHAL 70
Query: 72 QARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLIIA 131
A G +P+ ++ T GI G+ E DL++
Sbjct: 71 SASGRQVLLPETTPKGSPLIFRRW--------TPAGIMTAGRFGTSHPEGEIDIPDLVLV 122
Query: 132 PGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQKVDE 191
P +AF SG RLG+GGGYYD+ + L + + F Q V+ VP D +
Sbjct: 123 PFLAFDASGYRLGYGGGYYDRTLAMLDV------PAIGFGFAGQQVERVPRGPYDIPIPA 176
Query: 192 VI 193
++
Sbjct: 177 IV 178
>UniRef50_Q83FP9 Cluster: Putative uncharacterized protein; n=2;
Tropheryma whipplei|Rep: Putative uncharacterized
protein - Tropheryma whipplei (strain Twist) (Whipple's
bacillus)
Length = 203
Score = 51.6 bits (118), Expect = 1e-05
Identities = 23/67 (34%), Positives = 42/67 (62%), Gaps = 4/67 (5%)
Query: 127 DLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQD 186
D+++ P A + G RLG G GYYD+++ ++ + P + AV F+ ++ DE+P N+ D
Sbjct: 120 DVMLIPAAAVDKRGYRLGWGKGYYDRYLARVK---RSIP-VFAVVFDNEIFDEIPINDWD 175
Query: 187 QKVDEVI 193
+K+ V+
Sbjct: 176 KKLTGVV 182
>UniRef50_Q2S230 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Salinibacter ruber DSM 13855|Rep:
5-formyltetrahydrofolate cyclo-ligase - Salinibacter
ruber (strain DSM 13855)
Length = 195
Score = 51.6 bits (118), Expect = 1e-05
Identities = 38/187 (20%), Positives = 77/187 (41%), Gaps = 9/187 (4%)
Query: 9 AKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALY--MSTENEIDTAP 66
AK R + +L+ + +S ++ + + + + +Y ++ + E+DT P
Sbjct: 8 AKTSWRRRFRSYRRSLSARSCRARSSLIVHRALGAPPVAPAQVVHVYWPITAQREVDTRP 67
Query: 67 LIKHIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGL 126
LI ++AR +P LE P + ++ + + G +
Sbjct: 68 LIALLRARDVEVVLPVVTSFEAETPTLEHR-RYDGPGSLTANRWDIREPKHTERVPPGAI 126
Query: 127 DLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQD 186
D++ P + + G R+GHG GYYD F+ ++ A VA+ + +V +P D
Sbjct: 127 DVVFVPALGVGQDGHRIGHGSGYYDAFLQSV------ACLRVALTYEACLVPSLPNASHD 180
Query: 187 QKVDEVI 193
V ++
Sbjct: 181 VPVTTIV 187
>UniRef50_Q0BZ02 Cluster: 5-formyltetrahydrofolate cyclo-ligase
family protein; n=1; Hyphomonas neptunium ATCC
15444|Rep: 5-formyltetrahydrofolate cyclo-ligase family
protein - Hyphomonas neptunium (strain ATCC 15444)
Length = 207
Score = 51.2 bits (117), Expect = 2e-05
Identities = 36/139 (25%), Positives = 64/139 (46%), Gaps = 10/139 (7%)
Query: 55 YMSTENEIDTAPLIKHIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKD 114
Y++ E+D PL++ + GA +P+ + G+ + + G+S+ D
Sbjct: 51 YVAINEELDPFPLMERLARAGAELCLPRMEETGISWRLWSPGEP--LDRRPFGLSEPSAD 108
Query: 115 QARDDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNC 174
+ T L++ P +A+ G+RLG+G G+YD + LR A+A+
Sbjct: 109 AP--EVTPT----LVLTPLLAYDTLGNRLGYGRGHYDAALEKLRAKGRAF--ACAIAYAA 160
Query: 175 QVVDEVPTNEQDQKVDEVI 193
Q +D+VP DQ +D I
Sbjct: 161 QQIDKVPCEPHDQPLDWAI 179
>UniRef50_A5EXF0 Cluster: 5-formyltetrahydrofolate cyclo-ligase
family protein; n=1; Dichelobacter nodosus VCS1703A|Rep:
5-formyltetrahydrofolate cyclo-ligase family protein -
Dichelobacter nodosus (strain VCS1703A)
Length = 193
Score = 51.2 bits (117), Expect = 2e-05
Identities = 45/180 (25%), Positives = 79/180 (43%), Gaps = 9/180 (5%)
Query: 14 RNEIAAKIAALTNEEKKRQSQIVYEKVINH-SWYKSSSRIALYMSTENEIDTAPLIKHIQ 72
R E+ AK AA+ + +SQ + ++ + I L++S EIDT LI+ +
Sbjct: 8 RKEVRAKRAAICGAVRATKSQQASQFILEFMQQIEPVEEIGLFLSIAEEIDTHYLIETLF 67
Query: 73 ARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLD-LIIA 131
R F+P + +T+ +G ++DA + +++A
Sbjct: 68 QRQKKLFLPIVTAKGAALQWRAYYQGETL---NNGALNIPVPAPKNDAPDRQNPPKMVVA 124
Query: 132 PGVAFSRSGDRLGHGGGYYDK-FITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQKVD 190
P VA+ G R+G GGG+YD+ F +R AP ++ +A+ CQ + D +D
Sbjct: 125 PLVAYDACGHRIGMGGGFYDRSFAGKVR---GQAPYLIGMAYACQEIPLFTAERWDIPLD 181
>UniRef50_A1B1U2 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Paracoccus denitrificans PD1222|Rep:
5-formyltetrahydrofolate cyclo-ligase - Paracoccus
denitrificans (strain Pd 1222)
Length = 194
Score = 51.2 bits (117), Expect = 2e-05
Identities = 23/67 (34%), Positives = 38/67 (56%), Gaps = 2/67 (2%)
Query: 127 DLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQD 186
+++I P F R+G RLG+GGG+YD+ + LR A + +A+ Q + +P D
Sbjct: 106 EVLIVPLAGFDRAGHRLGYGGGFYDRTLAGLRAQRPVA--AIGLAYAVQEIRAIPAEATD 163
Query: 187 QKVDEVI 193
Q +D +I
Sbjct: 164 QPLDLII 170
>UniRef50_Q5SHW9 Cluster: 5-formyltetrahydrofolate cyclo-ligase
family protein; n=2; Thermus thermophilus|Rep:
5-formyltetrahydrofolate cyclo-ligase family protein -
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
Length = 184
Score = 50.8 bits (116), Expect = 2e-05
Identities = 19/33 (57%), Positives = 26/33 (78%)
Query: 126 LDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLR 158
LDL++ PG+AF R G RLGHG G+YD+F+ +R
Sbjct: 103 LDLVVVPGLAFDREGYRLGHGQGFYDRFLKEVR 135
>UniRef50_Q3B454 Cluster: 5-formyltetrahydrofolate cyclo-ligase,
putative; n=1; Pelodictyon luteolum DSM 273|Rep:
5-formyltetrahydrofolate cyclo-ligase, putative -
Pelodictyon luteolum (strain DSM 273) (Chlorobium
luteolum (strain DSM273))
Length = 213
Score = 50.8 bits (116), Expect = 2e-05
Identities = 42/151 (27%), Positives = 68/151 (45%), Gaps = 8/151 (5%)
Query: 47 KSSSRIALY--MSTENEIDTAPLIKHIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKT 104
K + + LY M E+DTA L + A VP G E G
Sbjct: 43 KGARAVHLYLPMKAAVEMDTASLACGLAAMDIPLMVPVIDCGNDYRNEDEEGGRLVSVVY 102
Query: 105 KHGI----SQHGKDQARDDAL-ETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRL 159
+ G+ S G + + +L + +D ++ P VA RSG RLG+G G+YD+F+ L+
Sbjct: 103 RPGMPLVRSCFGSPEPLERSLGDEYMIDAVVVPLVAVDRSGYRLGYGKGFYDRFLARLQ- 161
Query: 160 NPETAPKIVAVAFNCQVVDEVPTNEQDQKVD 190
+ P + F+ Q+ D +P + D+ +D
Sbjct: 162 HMGVRPCRIGFGFSMQLHDRLPCDPWDEPLD 192
>UniRef50_A6DHI6 Cluster: Putative uncharacterized protein; n=1;
Lentisphaera araneosa HTCC2155|Rep: Putative
uncharacterized protein - Lentisphaera araneosa HTCC2155
Length = 181
Score = 50.8 bits (116), Expect = 2e-05
Identities = 23/72 (31%), Positives = 39/72 (54%), Gaps = 5/72 (6%)
Query: 122 ETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVP 181
E +D P +AF R G+RLG GGG+YD+ + + + V V ++ Q++ EVP
Sbjct: 103 ELPAIDFCFIPALAFDRRGNRLGRGGGFYDRLLAKYSIGVK-----VGVCYDFQLIGEVP 157
Query: 182 TNEQDQKVDEVI 193
+ D +D ++
Sbjct: 158 KEDHDFTMDFIL 169
>UniRef50_A3UGX7 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Oceanicaulis alexandrii HTCC2633|Rep:
5-formyltetrahydrofolate cyclo-ligase - Oceanicaulis
alexandrii HTCC2633
Length = 191
Score = 50.8 bits (116), Expect = 2e-05
Identities = 40/157 (25%), Positives = 69/157 (43%), Gaps = 10/157 (6%)
Query: 38 EKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQARGAAAFVPQYAGGRMRMLHLETGD 97
E+ + W K +A Y + +EID PL++ A +P ++
Sbjct: 34 EQFPDRLWPKVRQVVAGYAAIGDEIDPLPLLETFALEQARIALPCVVAKDQPLIFRSWTL 93
Query: 98 EQTMPKTKHGISQHGKDQARDDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNL 157
+Q + G + A L L++ P V F G RLG+GGG+YD+ + L
Sbjct: 94 DQLLEPGAFGTRE---PAATHPELTP---SLVLVPLVGFDLKGRRLGYGGGFYDRTLEAL 147
Query: 158 RL-NPETAPKIVAVAFNCQVVDEVPTNEQDQKVDEVI 193
+ P T +V +A+ Q +++VP D ++D V+
Sbjct: 148 KAQGPLT---VVGLAYEAQRLNKVPAESHDVRMDWVV 181
>UniRef50_Q75BE9 Cluster: ADL385Cp; n=1; Eremothecium gossypii|Rep:
ADL385Cp - Ashbya gossypii (Yeast) (Eremothecium
gossypii)
Length = 218
Score = 50.4 bits (115), Expect = 3e-05
Identities = 35/115 (30%), Positives = 56/115 (48%), Gaps = 8/115 (6%)
Query: 84 AGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETG-----GLDLIIAPGVAF-S 137
AG MR HL Q+M + + GK R+ E +D+++ PG+ F +
Sbjct: 86 AGSHMRR-HLTFYHMQSMAAVR-ALRPQGKYGLREPPAEAPPPALPDVDVVLMPGLGFCA 143
Query: 138 RSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQKVDEV 192
+G RLG G GYYD +++ + P +V +A + Q++ VP DQ +D V
Sbjct: 144 DTGARLGRGAGYYDNYVSRTQQLHGRRPLLVGLALSQQLMLHVPLEPHDQCLDAV 198
>UniRef50_Q4FR52 Cluster: Possible 5-formyltetrahydrofolate
cyclo-ligase; n=3; Psychrobacter|Rep: Possible
5-formyltetrahydrofolate cyclo-ligase - Psychrobacter
arcticum
Length = 230
Score = 50.0 bits (114), Expect = 4e-05
Identities = 37/149 (24%), Positives = 62/149 (41%), Gaps = 7/149 (4%)
Query: 50 SRIALYMSTENEIDTAPLIKHIQARGAAAFVPQYAG-----GRMRMLHLETGDEQTMPKT 104
+RI LY E+ T PL+ Q G ++P R+R + + +P
Sbjct: 76 ARIGLYYDGFGELPTQPLLDWCQRLGYLPYLPVVGSLGQHDKRLRFVPIYHAKLLNIPTR 135
Query: 105 KHGISQHGKDQARDDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETA 164
H + R L LD+II P A ++G+R+G G G+YD +
Sbjct: 136 IHSLGMKQNHHRR--LLWAAELDVIICPLTAVDKNGNRMGMGSGFYDTTLGKSYQAGAKK 193
Query: 165 PKIVAVAFNCQVVDEVPTNEQDQKVDEVI 193
P + ++ QVV+++ D +D +I
Sbjct: 194 PLKIGWCYDFQVVEQLDRQPWDVPLDGLI 222
>UniRef50_A0LR79 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Acidothermus cellulolyticus 11B|Rep:
5-formyltetrahydrofolate cyclo-ligase - Acidothermus
cellulolyticus (strain ATCC 43068 / 11B)
Length = 202
Score = 50.0 bits (114), Expect = 4e-05
Identities = 50/186 (26%), Positives = 81/186 (43%), Gaps = 8/186 (4%)
Query: 9 AKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLI 68
AKA LR + A A T ++ + + + S + A+Y++ E T LI
Sbjct: 10 AKAGLRRTLLAARAQRTPAARREAGRRIAAAAADLLGDWSPAVAAVYLAIGTEPPTDQLI 69
Query: 69 KHIQARGAAAFVPQYAG-GRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLD 127
+ RG VP G + D T P + + +A+ T D
Sbjct: 70 AVLADRGCRLIVPILRDDGDLDWTPYHPADP-TEPGLRGTLIPTQPRALGVEAVSTA--D 126
Query: 128 LIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQ 187
LI+ P +A +G RLG GGG YD+ + R +P + VAV ++ ++V +P + DQ
Sbjct: 127 LIVVPALAVDPTGVRLGRGGGGYDRALR--RRSPGSL--TVAVIYDDELVPSLPEADHDQ 182
Query: 188 KVDEVI 193
+VD +
Sbjct: 183 RVDAAL 188
>UniRef50_UPI000050F91E Cluster: COG0212: 5-formyltetrahydrofolate
cyclo-ligase; n=1; Brevibacterium linens BL2|Rep:
COG0212: 5-formyltetrahydrofolate cyclo-ligase -
Brevibacterium linens BL2
Length = 224
Score = 49.6 bits (113), Expect = 5e-05
Identities = 32/101 (31%), Positives = 42/101 (41%), Gaps = 3/101 (2%)
Query: 55 YMSTENEIDTAPLIKHIQARGAAAFVPQYAG-GRMRMLHLETGDEQTM-PKTKHGISQHG 112
Y + E D P I A G ++P G M TG T+ P+ K GI +
Sbjct: 53 YAALAGEPDLDPTIDRFLAHGGTVYLPVVTSVGHALMFGAVTGSMSTLEPRGKWGIREPS 112
Query: 113 KDQARDDALETG-GLDLIIAPGVAFSRSGDRLGHGGGYYDK 152
L DLI P + F G RLG+GGG+YD+
Sbjct: 113 PSLTASALLAAEVAPDLIFVPALGFGPGGARLGNGGGFYDR 153
>UniRef50_Q6NIB6 Cluster: Putative uncharacterized protein; n=1;
Corynebacterium diphtheriae|Rep: Putative
uncharacterized protein - Corynebacterium diphtheriae
Length = 194
Score = 49.6 bits (113), Expect = 5e-05
Identities = 46/189 (24%), Positives = 77/189 (40%), Gaps = 11/189 (5%)
Query: 9 AKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLI 68
AK RN I A A + + + + ++ +++R A YM E
Sbjct: 10 AKKNARNRIRAARLARSTADLHADNAAILNQLTALIRTINATRAAAYMPEVTEPGGVDFA 69
Query: 69 KHIQARGAAAFVPQYAGGRMRML-HLETGDEQTMPKTKHGISQHGKDQARDDALETGGLD 127
++ + ++P+ R + H GD ++ + GI + D L +D
Sbjct: 70 DNLTGILSELWIPKSLPNRQLVWGHYSGGD--SVERGTFGILEPTTPSRSSDILHD--VD 125
Query: 128 LIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQ 187
LII P + + SG RLG G GYYD+ + + A VA+ F+ +V +P D
Sbjct: 126 LIIVPALGITPSGRRLGQGAGYYDRALAGV------ATPTVAILFDSEVNTTIPFEPHDA 179
Query: 188 KVDEVIFAE 196
D +I E
Sbjct: 180 TCDWIITPE 188
>UniRef50_Q4E7I6 Cluster: Protein; n=5; Wolbachia|Rep: Protein -
Wolbachia endosymbiont of Drosophila simulans
Length = 183
Score = 49.2 bits (112), Expect = 6e-05
Identities = 26/67 (38%), Positives = 35/67 (52%), Gaps = 3/67 (4%)
Query: 127 DLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQD 186
D II P +AF +RLG GGG+YD I LR + VA+ Q +P + D
Sbjct: 101 DTIITPVIAFDDHFNRLGFGGGWYDTMIKKLR---PLGKIFIGVAYEKQYCKNLPVEQHD 157
Query: 187 QKVDEVI 193
QK+D +I
Sbjct: 158 QKLDIII 164
>UniRef50_Q1GTI6 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Sphingopyxis alaskensis|Rep:
5-formyltetrahydrofolate cyclo-ligase - Sphingopyxis
alaskensis (Sphingomonas alaskensis)
Length = 197
Score = 49.2 bits (112), Expect = 6e-05
Identities = 35/142 (24%), Positives = 60/142 (42%), Gaps = 12/142 (8%)
Query: 52 IALYMSTENEIDTAPLIKHIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQH 111
+ Y++ +E D P++ + A GA A +P +AG M +++ G Q
Sbjct: 56 VGAYVAHGDEPDVLPMLADLAATGALA-LPHHAGRVAEMRFRRWRPGESLVTGPWGTRQP 114
Query: 112 GKDQARDDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVA 171
DD I P V F R G R+G GGG+YD++ A + +
Sbjct: 115 ------DDGAPLAEPHAIFCPLVGFDRRGGRIGQGGGHYDRYFA-----AHPAALRIGIG 163
Query: 172 FNCQVVDEVPTNEQDQKVDEVI 193
++ Q +D P + D +D ++
Sbjct: 164 WSVQEIDACPRDSADIALDAIL 185
>UniRef50_A5CEL8 Cluster: 5-Formyltetrahydrofolate cyclo-ligase;
n=1; Orientia tsutsugamushi Boryong|Rep:
5-Formyltetrahydrofolate cyclo-ligase - Orientia
tsutsugamushi (strain Boryong) (Rickettsia
tsutsugamushi)
Length = 190
Score = 49.2 bits (112), Expect = 6e-05
Identities = 24/66 (36%), Positives = 40/66 (60%), Gaps = 3/66 (4%)
Query: 129 IIAPGVAFSRSGDRLGHGGGYYDKFITNLR-LNPETAPKIVAVAFNCQVVDEVPTNEQDQ 187
++ PG+ F +G R+G G GYYD++I+ +R +N + V F+ Q+ + VP DQ
Sbjct: 119 LLVPGLVFDVAGYRIGFGKGYYDQYISQVRSINSNNI--AIGVCFDVQLRNFVPRELHDQ 176
Query: 188 KVDEVI 193
K+D +I
Sbjct: 177 KMDYII 182
>UniRef50_A0NNE7 Cluster: Putative uncharacterized protein; n=1;
Stappia aggregata IAM 12614|Rep: Putative
uncharacterized protein - Stappia aggregata IAM 12614
Length = 192
Score = 49.2 bits (112), Expect = 6e-05
Identities = 36/143 (25%), Positives = 65/143 (45%), Gaps = 12/143 (8%)
Query: 52 IALYMSTENEIDTAPLIKHIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQH 111
+A + +EID PL+ ++ G +P G + LE E + G S+
Sbjct: 52 VAGFWPIRDEIDPRPLMDRLRQLGHPLCLPVMTGPSLIFRRLERDTE--LVSAGFGTSEP 109
Query: 112 GKDQARDDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKI-VAV 170
G E D+++ P F G R+G+G +YD I L+ ++ P + + +
Sbjct: 110 GPSS------EEVRPDVLLMPLAGFDGRGTRIGYGKAFYDTTIAKLQ---QSGPLLCIGL 160
Query: 171 AFNCQVVDEVPTNEQDQKVDEVI 193
AF+ Q VD VP+ D+ ++ ++
Sbjct: 161 AFSVQEVDHVPSEAHDKPLNGIL 183
>UniRef50_Q89U90 Cluster: Blr1527 protein; n=1; Bradyrhizobium
japonicum|Rep: Blr1527 protein - Bradyrhizobium
japonicum
Length = 244
Score = 48.8 bits (111), Expect = 8e-05
Identities = 45/186 (24%), Positives = 86/186 (46%), Gaps = 11/186 (5%)
Query: 9 AKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLI 68
+KA LR + AK AL+ +++ + + ++ + S ++ Y +EID L+
Sbjct: 50 SKAELRAKALAKRDALSEKKRAAAATKLAKRGLPFKLLPGSI-VSGYSPIRSEIDPMQLL 108
Query: 69 KHIQARGAAAFVPQY-AGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLD 127
+ + GA +P A G+ + + +++ M GI + A + + D
Sbjct: 109 RKLAEEGARLALPCVTARGQSLVFRIFHPNDRLMLGPL-GIPE--PSPAASEVIP----D 161
Query: 128 LIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQ 187
+++ P AF R G R+G+G G+YD +LR + + +AF Q ++ VP D
Sbjct: 162 IMLTPLAAFDRLGHRIGYGAGHYDFTFAHLRKTKQIVG--IGLAFAAQEIEAVPALSHDV 219
Query: 188 KVDEVI 193
+D V+
Sbjct: 220 ALDYVL 225
>UniRef50_Q477X4 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=1; Dechloromonas aromatica RCB|Rep:
5-formyltetrahydrofolate cyclo-ligase - Dechloromonas
aromatica (strain RCB)
Length = 192
Score = 48.8 bits (111), Expect = 8e-05
Identities = 48/194 (24%), Positives = 86/194 (44%), Gaps = 14/194 (7%)
Query: 1 MSPIKPNPA-KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTE 59
+ P + N A + +LR E+ A+ AL++ E S + E+++ + + A +
Sbjct: 2 VEPNEDNTAWRRVLRREMVARRGALSDAEHAGLSARIVEQLL--AALPTPRVFAFCWPIK 59
Query: 60 NEIDTAPLIKHIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDD 119
+E D +++ RGA A +P + E + ++GI A D
Sbjct: 60 HEPDVRAVVESWAMRGAQAALPVVMAEDTPLAFRLWTPEMVLEMDRYGIPT---PTAGDL 116
Query: 120 ALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDE 179
+ D+I+ P F +G RLG+GGGY+D+ T L+P P V V F +
Sbjct: 117 VVP----DMILLPLNGFDAAGYRLGYGGGYFDR--TLAALSPR--PLAVGVGFEVNRLAS 168
Query: 180 VPTNEQDQKVDEVI 193
+ DQ++D ++
Sbjct: 169 IRPEVHDQRLDWIV 182
>UniRef50_A7B9R4 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 214
Score = 48.8 bits (111), Expect = 8e-05
Identities = 27/69 (39%), Positives = 42/69 (60%), Gaps = 6/69 (8%)
Query: 127 DLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDE--VPTNE 184
DLI+ P +A S G RLG GGG+YD+ +T+ +P T +VAV F+ +V++ +P
Sbjct: 139 DLIVIPALAASADGTRLGQGGGWYDRALTH--RSPGT--PVVAVIFDDEVLEAEIIPAEP 194
Query: 185 QDQKVDEVI 193
D VD ++
Sbjct: 195 HDVPVDGIV 203
>UniRef50_A2U3L0 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=2; Polaribacter|Rep: 5-formyltetrahydrofolate
cyclo-ligase - Polaribacter dokdonensis MED152
Length = 183
Score = 48.8 bits (111), Expect = 8e-05
Identities = 48/188 (25%), Positives = 88/188 (46%), Gaps = 13/188 (6%)
Query: 10 KALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYK-SSSRIALYMSTENEIDTAPLI 68
K+ LR K L+ ++ + +YE+V N + ++ I L + EIDT P+I
Sbjct: 3 KSELRKIYKEKRQQLSANVIQQFTSNIYEQVYNLDISQVKTAHIFLTLKKFKEIDTTPII 62
Query: 69 KHIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDL 128
++++ V + + H + + K+ I + K+ + A ET LDL
Sbjct: 63 DYLRSENIKIVVSKSDFTNNTLSHFYLEKDTQIELNKYEIPEP-KNAIQ--AKETD-LDL 118
Query: 129 IIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFN-CQVVDEV-PTNEQD 186
+ P + + R+G+G G+YD+F+ R + ++ V N + VDE+ NE D
Sbjct: 119 VFVPLLISDENNFRVGYGKGFYDRFLAKCRKD------VITVGLNFFKPVDEITDKNEFD 172
Query: 187 QKVDEVIF 194
+D+VI+
Sbjct: 173 IPLDKVIY 180
>UniRef50_Q1IX36 Cluster: 5-formyltetrahydrofolate cyclo-ligase;
n=2; Deinococcus|Rep: 5-formyltetrahydrofolate
cyclo-ligase - Deinococcus geothermalis (strain DSM
11300)
Length = 184
Score = 48.4 bits (110), Expect = 1e-04
Identities = 31/84 (36%), Positives = 43/84 (51%), Gaps = 8/84 (9%)
Query: 108 ISQHGKDQARDDALETG--GLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAP 165
+S+ G Q DA G +D ++ P +AF R G RLG+GGG+YD RL P
Sbjct: 93 VSRFGALQPPADAPRVGLEMVDAVLLPALAFDRRGVRLGYGGGFYD------RLLPGFTG 146
Query: 166 KIVAVAFNCQVVDEVPTNEQDQKV 189
V V VVD++P+ D +V
Sbjct: 147 LTVGVVGEALVVDKLPSEAHDLRV 170
>UniRef50_UPI0000E87FAB Cluster: 5-formyltetrahydrofolate
cyclo-ligase family protein; n=1; Methylophilales
bacterium HTCC2181|Rep: 5-formyltetrahydrofolate
cyclo-ligase family protein - Methylophilales bacterium
HTCC2181
Length = 188
Score = 48.0 bits (109), Expect = 1e-04
Identities = 34/133 (25%), Positives = 62/133 (46%), Gaps = 11/133 (8%)
Query: 29 KKRQSQIVYEKVINHSWYKSSS-RIALYMSTENEIDTAPLIKHIQARGAAAFVP--QYAG 85
++ S++V+ + YK L + + EI+T +I++ VP +A
Sbjct: 23 EEESSKLVHNSIALIEHYKPKCMHCFLPIHSRGEINTTAIIQYCWENNIKVLVPVSNFAD 82
Query: 86 GRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGG-LDLIIAPGVAFSRSGDRLG 144
G ++ + Q P TK + + + D E G +D++I P +AF G R+G
Sbjct: 83 GTLK-------NAQFSPHTKISQTHYNITEPIDPVWEEGNDIDMVITPLLAFDCKGYRVG 135
Query: 145 HGGGYYDKFITNL 157
+G G+YD+F +L
Sbjct: 136 YGKGFYDRFFASL 148
>UniRef50_Q6FD61 Cluster: Putative ligase; n=3; Acinetobacter|Rep:
Putative ligase - Acinetobacter sp. (strain ADP1)
Length = 211
Score = 48.0 bits (109), Expect = 1e-04
Identities = 36/161 (22%), Positives = 68/161 (42%), Gaps = 5/161 (3%)
Query: 37 YEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQARGAAAFVPQYAGGRMRMLHLETG 96
+ + + ++ SS I LY+ EI T +I G ++P ++ +E
Sbjct: 48 FRQFLKNTRLTSSQNIGLYLHAFGEIYTRKIILECFKLGKKVYLPMICNVNQTLVWIEIT 107
Query: 97 DEQTMPKTKHGISQHGKDQARDDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITN 156
Q + + + K+ LDL++ P VA G R+G GGG+YD+ +
Sbjct: 108 KTQYFNRRFYHHALGMKEPMASRGHHVSHLDLLLMPLVACDDQGTRMGMGGGFYDRTL-- 165
Query: 157 LRLNPETAPKIVAVAFNCQVVDEVPTNEQ-DQKVDEVIFAE 196
+ P + +A + Q +D+ + DQ +D ++ E
Sbjct: 166 --VTSSHTPFRLGLAHSFQYLDQKLFRQSWDQPLDALLTPE 204
>UniRef50_A5V9J0 Cluster: 5-formyltetrahydrofolate cyclo-ligase
precursor; n=1; Sphingomonas wittichii RW1|Rep:
5-formyltetrahydrofolate cyclo-ligase precursor -
Sphingomonas wittichii RW1
Length = 206
Score = 48.0 bits (109), Expect = 1e-04
Identities = 44/156 (28%), Positives = 70/156 (44%), Gaps = 16/156 (10%)
Query: 3 PIKPNPAKALLRNEIAAK----IAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMST 58
P+ P+K LR E+ A + L E+ R + + ++ + S IA Y++
Sbjct: 14 PMAAEPSKPALRAELRAVRDAFVLDLAPGERARLEALAADHLMRVAGGARS--IAFYVAM 71
Query: 59 ENEIDTAPLIKHIQARGAAAFVP--QYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQA 116
+E+ A I ARG A +P + MR L GD + G+SQ + A
Sbjct: 72 GSEMGCAAAIAATAARGIAVALPHVESRSAPMRFLRWTPGDP--LETGWRGLSQPAAESA 129
Query: 117 RDDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDK 152
D DLI+AP + F + +R+G G G+YD+
Sbjct: 130 GIDP------DLIVAPLLGFDSALNRIGQGAGFYDR 159
>UniRef50_Q2G6W2 Cluster: 5-formyltetrahydrofolate cyclo-ligase
precursor; n=3; Sphingomonadales|Rep:
5-formyltetrahydrofolate cyclo-ligase precursor -
Novosphingobium aromaticivorans (strain DSM 12444)
Length = 195
Score = 47.6 bits (108), Expect = 2e-04
Identities = 22/67 (32%), Positives = 37/67 (55%), Gaps = 5/67 (7%)
Query: 127 DLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQD 186
+++ P V F G RLG GGG+YD++I A + +A++CQ+VD +P D
Sbjct: 121 EVVFVPLVGFDAEGGRLGQGGGHYDRWI-----EAHPAAVRIGLAWDCQLVDRLPRETHD 175
Query: 187 QKVDEVI 193
+ + V+
Sbjct: 176 RALHAVV 182
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.315 0.132 0.376
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 226,509,387
Number of Sequences: 1657284
Number of extensions: 9401185
Number of successful extensions: 22106
Number of sequences better than 10.0: 348
Number of HSP's better than 10.0 without gapping: 307
Number of HSP's successfully gapped in prelim test: 41
Number of HSP's that attempted gapping in prelim test: 21506
Number of HSP's gapped (non-prelim): 376
length of query: 196
length of database: 575,637,011
effective HSP length: 97
effective length of query: 99
effective length of database: 414,880,463
effective search space: 41073165837
effective search space used: 41073165837
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.6 bits)
S2: 70 (32.3 bits)
- SilkBase 1999-2023 -