Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA002071-TA|BGIBMGA002071-PA|IPR002698|5-
formyltetrahydrofolate cyclo-ligase
(196 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
L38928-1|AAC41945.1| 203|Homo sapiens 5,10-methenyltetrahydrofo... 165 1e-40
BC019921-1|AAH19921.1| 203|Homo sapiens 5,10-methenyltetrahydro... 165 1e-40
BC012417-1|AAH12417.1| 193|Homo sapiens MTHFS protein protein. 162 8e-40
BC037852-1|AAH37852.1| 94|Homo sapiens MTHFS protein protein. 78 2e-14
BC112059-1|AAI12060.1| 383|Homo sapiens methenyltetrahydrofolat... 38 0.030
BC112057-1|AAI12058.1| 383|Homo sapiens methenyltetrahydrofolat... 38 0.030
AK023955-1|BAB14739.1| 382|Homo sapiens protein ( Homo sapiens ... 38 0.030
AK023060-1|BAB14383.1| 371|Homo sapiens protein ( Homo sapiens ... 37 0.040
Z97054-12|CAI42656.1| 3407|Homo sapiens upstream regulatory elem... 32 1.1
Z97054-10|CAI42654.1| 4374|Homo sapiens upstream regulatory elem... 32 1.1
Z94044-4|CAI42354.1| 4374|Homo sapiens upstream regulatory eleme... 32 1.1
DQ097177-1|AAY98258.1| 4374|Homo sapiens Mcl-1 ubiquitin ligase ... 32 1.1
AY929612-1|AAX24125.1| 4374|Homo sapiens LASU1 protein. 32 1.1
AY772009-1|AAV90838.1| 4374|Homo sapiens ARF-binding protein 1 p... 32 1.1
AL592046-4|CAI39581.1| 3407|Homo sapiens upstream regulatory ele... 32 1.1
AL592046-3|CAI39580.1| 4374|Homo sapiens upstream regulatory ele... 32 1.1
AB071605-1|BAC06833.1| 3360|Homo sapiens HECT domain protein LAS... 32 1.1
AB002310-1|BAA20771.2| 3192|Homo sapiens KIAA0312 protein. 32 1.1
BC027886-1|AAH27886.1| 355|Homo sapiens guanine nucleotide bind... 31 2.0
AL355535-1|CAI14668.1| 355|Homo sapiens guanine nucleotide bind... 31 2.0
AL353794-1|CAH74055.1| 355|Homo sapiens guanine nucleotide bind... 31 2.0
AL158159-3|CAI40937.1| 355|Homo sapiens guanine nucleotide bind... 31 2.0
AF493903-1|AAM12617.1| 355|Homo sapiens guanine nucleotide bind... 31 2.0
AF105201-1|AAD17944.1| 355|Homo sapiens G-protein alpha subunit... 31 2.0
AL356504-1|CAI19595.1| 4061|Homo sapiens filaggrin protein. 30 4.6
M69013-1|AAA58624.1| 359|Homo sapiens guanine nucleotide-bindin... 30 6.0
CR457004-1|CAG33285.1| 359|Homo sapiens GNA11 protein. 30 6.0
BC096227-1|AAH96227.1| 359|Homo sapiens guanine nucleotide bind... 30 6.0
BC096226-1|AAH96226.1| 359|Homo sapiens guanine nucleotide bind... 30 6.0
BC096225-1|AAH96225.1| 359|Homo sapiens guanine nucleotide bind... 30 6.0
BC089041-1|AAH89041.1| 359|Homo sapiens guanine nucleotide bind... 30 6.0
AF493900-1|AAM12614.1| 359|Homo sapiens guanine nucleotide bind... 30 6.0
AF011497-1|AAB64303.1| 359|Homo sapiens guanine nucleotide bind... 30 6.0
AC005262-1|AAC25615.1| 359|Homo sapiens GB11_HUMAN protein. 30 6.0
AB209435-1|BAD92672.1| 357|Homo sapiens Guanine nucleotide-bind... 30 6.0
U43083-1|AAB06875.1| 359|Homo sapiens G alpha-q protein. 29 8.0
U40038-1|AAC50363.1| 359|Homo sapiens GTP-binding protein alpha... 29 8.0
L76256-1|AAB39498.1| 359|Homo sapiens G alpha q protein. 29 8.0
L40629-1|AAA99950.1| 94|Homo sapiens GAQ protein. 29 8.0
BX537685-1|CAD97811.1| 520|Homo sapiens hypothetical protein pr... 29 8.0
BC075097-1|AAH75097.1| 359|Homo sapiens guanine nucleotide bind... 29 8.0
BC075096-1|AAH75096.1| 359|Homo sapiens guanine nucleotide bind... 29 8.0
BC069520-1|AAH69520.1| 359|Homo sapiens guanine nucleotide bind... 29 8.0
BC067850-1|AAH67850.1| 359|Homo sapiens guanine nucleotide bind... 29 8.0
BC057777-1|AAH57777.1| 359|Homo sapiens guanine nucleotide bind... 29 8.0
AL355535-2|CAI14669.1| 359|Homo sapiens guanine nucleotide bind... 29 8.0
AL160278-2|CAI15999.1| 359|Homo sapiens guanine nucleotide bind... 29 8.0
AL160268-2|CAI12198.1| 359|Homo sapiens guanine nucleotide bind... 29 8.0
AF493896-1|AAM12610.1| 359|Homo sapiens guanine nucleotide bind... 29 8.0
AF329284-1|AAG61117.1| 359|Homo sapiens G alpha q protein protein. 29 8.0
AF011496-1|AAB64301.1| 359|Homo sapiens GTP-binding protein alp... 29 8.0
>L38928-1|AAC41945.1| 203|Homo sapiens
5,10-methenyltetrahydrofolate synthetase protein.
Length = 203
Score = 165 bits (400), Expect = 1e-40
Identities = 81/199 (40%), Positives = 125/199 (62%), Gaps = 3/199 (1%)
Query: 1 MSPIKPNPAKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTEN 60
M+ + AK LR E+ ++ A++ EE+ RQS+++ +KVI HS Y+ S RI++++S ++
Sbjct: 1 MAAAAVSSAKRSLRGELKQRLRAMSAEERLRQSRVLSQKVIAHSEYQKSKRISIFLSMQD 60
Query: 61 EIDTAPLIKHIQARGAAAFVPQYA--GGRMRMLHLETGDE-QTMPKTKHGISQHGKDQAR 117
EI+T +IK I RG F+P+Y M M+ +E+ +E +PKT I Q G+ R
Sbjct: 61 EIETEEIIKDIFQRGKICFIPRYRFQSNHMDMVRIESPEEISLLPKTSWNIPQPGEGDVR 120
Query: 118 DDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVV 177
++AL TGGLDLI PG+ F + G+RLG G GYYD ++ + E P +A+AF Q+
Sbjct: 121 EEALSTGGLDLIFMPGLGFDKHGNRLGRGKGYYDAYLKRCLQHQEVKPYTLALAFKEQIC 180
Query: 178 DEVPTNEQDQKVDEVIFAE 196
+VP NE D KVDEV++ +
Sbjct: 181 LQVPVNENDMKVDEVLYED 199
>BC019921-1|AAH19921.1| 203|Homo sapiens
5,10-methenyltetrahydrofolate synthetase
(5-formyltetrahydrofolate cyclo-ligase protein.
Length = 203
Score = 165 bits (400), Expect = 1e-40
Identities = 81/199 (40%), Positives = 125/199 (62%), Gaps = 3/199 (1%)
Query: 1 MSPIKPNPAKALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTEN 60
M+ + AK LR E+ ++ A++ EE+ RQS+++ +KVI HS Y+ S RI++++S ++
Sbjct: 1 MAAAAVSSAKRSLRGELKQRLRAMSAEERLRQSRVLSQKVIAHSEYQKSKRISIFLSMQD 60
Query: 61 EIDTAPLIKHIQARGAAAFVPQYA--GGRMRMLHLETGDE-QTMPKTKHGISQHGKDQAR 117
EI+T +IK I RG F+P+Y M M+ +E+ +E +PKT I Q G+ R
Sbjct: 61 EIETEEIIKDIFQRGKICFIPRYRFQSNHMDMVRIESPEEISLLPKTSWNIPQPGEGDVR 120
Query: 118 DDALETGGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVV 177
++AL TGGLDLI PG+ F + G+RLG G GYYD ++ + E P +A+AF Q+
Sbjct: 121 EEALSTGGLDLIFMPGLGFDKHGNRLGRGKGYYDAYLKRCLQHQEVKPYTLALAFKEQIC 180
Query: 178 DEVPTNEQDQKVDEVIFAE 196
+VP NE D KVDEV++ +
Sbjct: 181 LQVPVNENDMKVDEVLYED 199
>BC012417-1|AAH12417.1| 193|Homo sapiens MTHFS protein protein.
Length = 193
Score = 162 bits (393), Expect = 8e-40
Identities = 78/187 (41%), Positives = 120/187 (64%), Gaps = 3/187 (1%)
Query: 13 LRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQ 72
LR E+ ++ A++ EE+ RQS+++ +KVI HS Y+ S RI++++S ++EI+T +IK I
Sbjct: 3 LRGELKQRLRAMSAEERLRQSRVLSQKVIAHSEYQKSKRISIFLSMQDEIETEEIIKDIF 62
Query: 73 ARGAAAFVPQYA--GGRMRMLHLETGDE-QTMPKTKHGISQHGKDQARDDALETGGLDLI 129
RG F+P+Y M M+ +E+ +E +PKT I Q G+ R++AL TGGLDLI
Sbjct: 63 QRGKICFIPRYRFQSNHMDMVRIESPEEISLLPKTSWNIPQPGEGDVREEALSTGGLDLI 122
Query: 130 IAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTNEQDQKV 189
PG+ F + G+RLG G GYYD ++ + E P +A+AF Q+ +VP NE D KV
Sbjct: 123 FMPGLGFDKHGNRLGRGKGYYDAYLKRCLQHQEVKPYTLALAFKEQICLQVPVNENDMKV 182
Query: 190 DEVIFAE 196
DEV++ +
Sbjct: 183 DEVLYED 189
>BC037852-1|AAH37852.1| 94|Homo sapiens MTHFS protein protein.
Length = 94
Score = 77.8 bits (183), Expect = 2e-14
Identities = 34/73 (46%), Positives = 47/73 (64%)
Query: 124 GGLDLIIAPGVAFSRSGDRLGHGGGYYDKFITNLRLNPETAPKIVAVAFNCQVVDEVPTN 183
GGLDLI PG+ F + G+RLG G GYYD ++ + E P +A+AF Q+ +VP N
Sbjct: 18 GGLDLIFMPGLGFDKHGNRLGRGKGYYDAYLKRCLQHQEVKPYTLALAFKEQICLQVPVN 77
Query: 184 EQDQKVDEVIFAE 196
E D KVDEV++ +
Sbjct: 78 ENDMKVDEVLYED 90
>BC112059-1|AAI12060.1| 383|Homo sapiens methenyltetrahydrofolate
synthetase domain containing protein.
Length = 383
Score = 37.5 bits (83), Expect = 0.030
Identities = 25/74 (33%), Positives = 38/74 (51%), Gaps = 8/74 (10%)
Query: 126 LDLIIAPGVAFSRSGDRLGHGGGY----YDKFITNLRLNPETAPKIVAVAFNCQVVD--E 179
+DL++ VA S G R+G G GY Y ++ ++ ET +V + +CQVVD E
Sbjct: 134 VDLVVVGSVAVSEKGWRIGKGEGYADLEYAMMVSMGAVSKET--PVVTIVHDCQVVDIPE 191
Query: 180 VPTNEQDQKVDEVI 193
E D VD ++
Sbjct: 192 ELVEEHDITVDYIL 205
>BC112057-1|AAI12058.1| 383|Homo sapiens methenyltetrahydrofolate
synthetase domain containing protein.
Length = 383
Score = 37.5 bits (83), Expect = 0.030
Identities = 25/74 (33%), Positives = 38/74 (51%), Gaps = 8/74 (10%)
Query: 126 LDLIIAPGVAFSRSGDRLGHGGGY----YDKFITNLRLNPETAPKIVAVAFNCQVVD--E 179
+DL++ VA S G R+G G GY Y ++ ++ ET +V + +CQVVD E
Sbjct: 134 VDLVVVGSVAVSEKGWRIGKGEGYADLEYAMMVSMGAVSKET--PVVTIVHDCQVVDIPE 191
Query: 180 VPTNEQDQKVDEVI 193
E D VD ++
Sbjct: 192 ELVEEHDITVDYIL 205
>AK023955-1|BAB14739.1| 382|Homo sapiens protein ( Homo sapiens
cDNA FLJ13893 fis, clone THYRO1001661. ).
Length = 382
Score = 37.5 bits (83), Expect = 0.030
Identities = 25/74 (33%), Positives = 38/74 (51%), Gaps = 8/74 (10%)
Query: 126 LDLIIAPGVAFSRSGDRLGHGGGY----YDKFITNLRLNPETAPKIVAVAFNCQVVD--E 179
+DL++ VA S G R+G G GY Y ++ ++ ET +V + +CQVVD E
Sbjct: 133 VDLVVVGSVAVSEKGWRIGKGEGYADLEYAMMVSMGAVSKET--PVVTIVHDCQVVDIPE 190
Query: 180 VPTNEQDQKVDEVI 193
E D VD ++
Sbjct: 191 ELVEEHDITVDYIL 204
>AK023060-1|BAB14383.1| 371|Homo sapiens protein ( Homo sapiens
cDNA FLJ12998 fis, clone NT2RP3000267. ).
Length = 371
Score = 37.1 bits (82), Expect = 0.040
Identities = 25/74 (33%), Positives = 38/74 (51%), Gaps = 8/74 (10%)
Query: 126 LDLIIAPGVAFSRSGDRLGHGGGY----YDKFITNLRLNPETAPKIVAVAFNCQVVD--E 179
+DL++ VA S G R+G G GY Y ++ ++ ET +V + +CQVVD E
Sbjct: 134 VDLVVVGSVAASEKGWRIGKGEGYADLEYAMMVSMGAVSKET--PVVTIVHDCQVVDIPE 191
Query: 180 VPTNEQDQKVDEVI 193
E D VD ++
Sbjct: 192 ELVEEHDITVDYIL 205
>Z97054-12|CAI42656.1| 3407|Homo sapiens upstream regulatory element
binding protein 1 (UREB1) protein.
Length = 3407
Score = 32.3 bits (70), Expect = 1.1
Identities = 15/42 (35%), Positives = 27/42 (64%)
Query: 11 ALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRI 52
A++ +IAA+ AL E++ RQ Q+++E++ HS + S I
Sbjct: 2116 AVMPPDIAAEAQALRREQEARQRQLMHERLFGHSSTSALSAI 2157
>Z97054-10|CAI42654.1| 4374|Homo sapiens upstream regulatory element
binding protein 1 (UREB1) protein.
Length = 4374
Score = 32.3 bits (70), Expect = 1.1
Identities = 15/42 (35%), Positives = 27/42 (64%)
Query: 11 ALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRI 52
A++ +IAA+ AL E++ RQ Q+++E++ HS + S I
Sbjct: 3083 AVMPPDIAAEAQALRREQEARQRQLMHERLFGHSSTSALSAI 3124
>Z94044-4|CAI42354.1| 4374|Homo sapiens upstream regulatory element
binding protein 1 (UREB1) protein.
Length = 4374
Score = 32.3 bits (70), Expect = 1.1
Identities = 15/42 (35%), Positives = 27/42 (64%)
Query: 11 ALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRI 52
A++ +IAA+ AL E++ RQ Q+++E++ HS + S I
Sbjct: 3083 AVMPPDIAAEAQALRREQEARQRQLMHERLFGHSSTSALSAI 3124
>DQ097177-1|AAY98258.1| 4374|Homo sapiens Mcl-1 ubiquitin ligase
protein.
Length = 4374
Score = 32.3 bits (70), Expect = 1.1
Identities = 15/42 (35%), Positives = 27/42 (64%)
Query: 11 ALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRI 52
A++ +IAA+ AL E++ RQ Q+++E++ HS + S I
Sbjct: 3083 AVMPPDIAAEAQALRREQEARQRQLMHERLFGHSSTSALSAI 3124
>AY929612-1|AAX24125.1| 4374|Homo sapiens LASU1 protein.
Length = 4374
Score = 32.3 bits (70), Expect = 1.1
Identities = 15/42 (35%), Positives = 27/42 (64%)
Query: 11 ALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRI 52
A++ +IAA+ AL E++ RQ Q+++E++ HS + S I
Sbjct: 3083 AVMPPDIAAEAQALRREQEARQRQLMHERLFGHSSTSALSAI 3124
>AY772009-1|AAV90838.1| 4374|Homo sapiens ARF-binding protein 1
protein.
Length = 4374
Score = 32.3 bits (70), Expect = 1.1
Identities = 15/42 (35%), Positives = 27/42 (64%)
Query: 11 ALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRI 52
A++ +IAA+ AL E++ RQ Q+++E++ HS + S I
Sbjct: 3083 AVMPPDIAAEAQALRREQEARQRQLMHERLFGHSSTSALSAI 3124
>AL592046-4|CAI39581.1| 3407|Homo sapiens upstream regulatory element
binding protein 1 (UREB1) protein.
Length = 3407
Score = 32.3 bits (70), Expect = 1.1
Identities = 15/42 (35%), Positives = 27/42 (64%)
Query: 11 ALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRI 52
A++ +IAA+ AL E++ RQ Q+++E++ HS + S I
Sbjct: 2116 AVMPPDIAAEAQALRREQEARQRQLMHERLFGHSSTSALSAI 2157
>AL592046-3|CAI39580.1| 4374|Homo sapiens upstream regulatory element
binding protein 1 (UREB1) protein.
Length = 4374
Score = 32.3 bits (70), Expect = 1.1
Identities = 15/42 (35%), Positives = 27/42 (64%)
Query: 11 ALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRI 52
A++ +IAA+ AL E++ RQ Q+++E++ HS + S I
Sbjct: 3083 AVMPPDIAAEAQALRREQEARQRQLMHERLFGHSSTSALSAI 3124
>AB071605-1|BAC06833.1| 3360|Homo sapiens HECT domain protein LASU1
protein.
Length = 3360
Score = 32.3 bits (70), Expect = 1.1
Identities = 15/42 (35%), Positives = 27/42 (64%)
Query: 11 ALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRI 52
A++ +IAA+ AL E++ RQ Q+++E++ HS + S I
Sbjct: 2069 AVMPPDIAAEAQALRREQEARQRQLMHERLFGHSSTSALSAI 2110
>AB002310-1|BAA20771.2| 3192|Homo sapiens KIAA0312 protein.
Length = 3192
Score = 32.3 bits (70), Expect = 1.1
Identities = 15/42 (35%), Positives = 27/42 (64%)
Query: 11 ALLRNEIAAKIAALTNEEKKRQSQIVYEKVINHSWYKSSSRI 52
A++ +IAA+ AL E++ RQ Q+++E++ HS + S I
Sbjct: 1901 AVMPPDIAAEAQALRREQEARQRQLMHERLFGHSSTSALSAI 1942
>BC027886-1|AAH27886.1| 355|Homo sapiens guanine nucleotide binding
protein (G protein), alpha 14 protein.
Length = 355
Score = 31.5 bits (68), Expect = 2.0
Identities = 13/65 (20%), Positives = 37/65 (56%), Gaps = 6/65 (9%)
Query: 21 IAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQARGAAAFV 80
+A NE + +S+ +++ +I + W+ +SS + L+++ ++ ++ + H+ ++
Sbjct: 235 LAECDNENRMEESKALFKTIITYPWFLNSS-VILFLNKKDLLEEKIMYSHL-----ISYF 288
Query: 81 PQYAG 85
P+Y G
Sbjct: 289 PEYTG 293
>AL355535-1|CAI14668.1| 355|Homo sapiens guanine nucleotide binding
protein (G protein), alpha 14 protein.
Length = 355
Score = 31.5 bits (68), Expect = 2.0
Identities = 13/65 (20%), Positives = 37/65 (56%), Gaps = 6/65 (9%)
Query: 21 IAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQARGAAAFV 80
+A NE + +S+ +++ +I + W+ +SS + L+++ ++ ++ + H+ ++
Sbjct: 235 LAECDNENRMEESKALFKTIITYPWFLNSS-VILFLNKKDLLEEKIMYSHL-----ISYF 288
Query: 81 PQYAG 85
P+Y G
Sbjct: 289 PEYTG 293
>AL353794-1|CAH74055.1| 355|Homo sapiens guanine nucleotide binding
protein (G protein), alpha 14 protein.
Length = 355
Score = 31.5 bits (68), Expect = 2.0
Identities = 13/65 (20%), Positives = 37/65 (56%), Gaps = 6/65 (9%)
Query: 21 IAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQARGAAAFV 80
+A NE + +S+ +++ +I + W+ +SS + L+++ ++ ++ + H+ ++
Sbjct: 235 LAECDNENRMEESKALFKTIITYPWFLNSS-VILFLNKKDLLEEKIMYSHL-----ISYF 288
Query: 81 PQYAG 85
P+Y G
Sbjct: 289 PEYTG 293
>AL158159-3|CAI40937.1| 355|Homo sapiens guanine nucleotide binding
protein (G protein), alpha 14 protein.
Length = 355
Score = 31.5 bits (68), Expect = 2.0
Identities = 13/65 (20%), Positives = 37/65 (56%), Gaps = 6/65 (9%)
Query: 21 IAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQARGAAAFV 80
+A NE + +S+ +++ +I + W+ +SS + L+++ ++ ++ + H+ ++
Sbjct: 235 LAECDNENRMEESKALFKTIITYPWFLNSS-VILFLNKKDLLEEKIMYSHL-----ISYF 288
Query: 81 PQYAG 85
P+Y G
Sbjct: 289 PEYTG 293
>AF493903-1|AAM12617.1| 355|Homo sapiens guanine nucleotide binding
protein alpha 14 protein.
Length = 355
Score = 31.5 bits (68), Expect = 2.0
Identities = 13/65 (20%), Positives = 37/65 (56%), Gaps = 6/65 (9%)
Query: 21 IAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQARGAAAFV 80
+A NE + +S+ +++ +I + W+ +SS + L+++ ++ ++ + H+ ++
Sbjct: 235 LAECDNENRMEESKALFKTIITYPWFLNSS-VILFLNKKDLLEEKIMYSHL-----ISYF 288
Query: 81 PQYAG 85
P+Y G
Sbjct: 289 PEYTG 293
>AF105201-1|AAD17944.1| 355|Homo sapiens G-protein alpha subunit 14
protein.
Length = 355
Score = 31.5 bits (68), Expect = 2.0
Identities = 13/65 (20%), Positives = 37/65 (56%), Gaps = 6/65 (9%)
Query: 21 IAALTNEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQARGAAAFV 80
+A NE + +S+ +++ +I + W+ +SS + L+++ ++ ++ + H+ ++
Sbjct: 235 LAECDNENRMEESKALFKTIITYPWFLNSS-VILFLNKKDLLEEKIMYSHL-----ISYF 288
Query: 81 PQYAG 85
P+Y G
Sbjct: 289 PEYTG 293
>AL356504-1|CAI19595.1| 4061|Homo sapiens filaggrin protein.
Length = 4061
Score = 30.3 bits (65), Expect = 4.6
Identities = 23/81 (28%), Positives = 32/81 (39%), Gaps = 9/81 (11%)
Query: 70 HIQARGAAAFVPQYAGGRMRMLHLETGDEQTMPKTKHGISQHGKDQARDDALETGGLDLI 129
H Q+ A GGR R H EQ ++H SQ G+D R + G
Sbjct: 1772 HEQSESAHGRTGPSTGGRQRSRH-----EQARDSSRHSASQEGQDTIRGHPGSSRG---- 1822
Query: 130 IAPGVAFSRSGDRLGHGGGYY 150
G + +S D GH G ++
Sbjct: 1823 GRQGSHYEQSVDSSGHSGSHH 1843
>M69013-1|AAA58624.1| 359|Homo sapiens guanine nucleotide-binding
regulatory protein protein.
Length = 359
Score = 29.9 bits (64), Expect = 6.0
Identities = 10/46 (21%), Positives = 29/46 (63%), Gaps = 1/46 (2%)
Query: 26 NEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHI 71
NE + +S+ ++ +I + W+++SS + L+++ ++ ++ L H+
Sbjct: 244 NENRMEESKALFRTIITYPWFQNSS-VILFLNKKDLLEDKILYSHL 288
>CR457004-1|CAG33285.1| 359|Homo sapiens GNA11 protein.
Length = 359
Score = 29.9 bits (64), Expect = 6.0
Identities = 10/46 (21%), Positives = 29/46 (63%), Gaps = 1/46 (2%)
Query: 26 NEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHI 71
NE + +S+ ++ +I + W+++SS + L+++ ++ ++ L H+
Sbjct: 244 NENRMEESKALFRTIITYPWFQNSS-VILFLNKKDLLEDKILYSHL 288
>BC096227-1|AAH96227.1| 359|Homo sapiens guanine nucleotide binding
protein (G protein), alpha 11 (Gq class) protein.
Length = 359
Score = 29.9 bits (64), Expect = 6.0
Identities = 10/46 (21%), Positives = 29/46 (63%), Gaps = 1/46 (2%)
Query: 26 NEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHI 71
NE + +S+ ++ +I + W+++SS + L+++ ++ ++ L H+
Sbjct: 244 NENRMEESKALFRTIITYPWFQNSS-VILFLNKKDLLEDKILYSHL 288
>BC096226-1|AAH96226.1| 359|Homo sapiens guanine nucleotide binding
protein (G protein), alpha 11 (Gq class) protein.
Length = 359
Score = 29.9 bits (64), Expect = 6.0
Identities = 10/46 (21%), Positives = 29/46 (63%), Gaps = 1/46 (2%)
Query: 26 NEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHI 71
NE + +S+ ++ +I + W+++SS + L+++ ++ ++ L H+
Sbjct: 244 NENRMEESKALFRTIITYPWFQNSS-VILFLNKKDLLEDKILYSHL 288
>BC096225-1|AAH96225.1| 359|Homo sapiens guanine nucleotide binding
protein (G protein), alpha 11 (Gq class) protein.
Length = 359
Score = 29.9 bits (64), Expect = 6.0
Identities = 10/46 (21%), Positives = 29/46 (63%), Gaps = 1/46 (2%)
Query: 26 NEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHI 71
NE + +S+ ++ +I + W+++SS + L+++ ++ ++ L H+
Sbjct: 244 NENRMEESKALFRTIITYPWFQNSS-VILFLNKKDLLEDKILYSHL 288
>BC089041-1|AAH89041.1| 359|Homo sapiens guanine nucleotide binding
protein (G protein), alpha 11 (Gq class) protein.
Length = 359
Score = 29.9 bits (64), Expect = 6.0
Identities = 10/46 (21%), Positives = 29/46 (63%), Gaps = 1/46 (2%)
Query: 26 NEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHI 71
NE + +S+ ++ +I + W+++SS + L+++ ++ ++ L H+
Sbjct: 244 NENRMEESKALFRTIITYPWFQNSS-VILFLNKKDLLEDKILYSHL 288
>AF493900-1|AAM12614.1| 359|Homo sapiens guanine nucleotide binding
protein alpha 11 protein.
Length = 359
Score = 29.9 bits (64), Expect = 6.0
Identities = 10/46 (21%), Positives = 29/46 (63%), Gaps = 1/46 (2%)
Query: 26 NEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHI 71
NE + +S+ ++ +I + W+++SS + L+++ ++ ++ L H+
Sbjct: 244 NENRMEESKALFRTIITYPWFQNSS-VILFLNKKDLLEDKILYSHL 288
>AF011497-1|AAB64303.1| 359|Homo sapiens guanine nucleotide binding
protein alpha 11 subunit protein.
Length = 359
Score = 29.9 bits (64), Expect = 6.0
Identities = 10/46 (21%), Positives = 29/46 (63%), Gaps = 1/46 (2%)
Query: 26 NEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHI 71
NE + +S+ ++ +I + W+++SS + L+++ ++ ++ L H+
Sbjct: 244 NENRMEESKALFRTIITYPWFQNSS-VILFLNKKDLLEDKILYSHL 288
>AC005262-1|AAC25615.1| 359|Homo sapiens GB11_HUMAN protein.
Length = 359
Score = 29.9 bits (64), Expect = 6.0
Identities = 10/46 (21%), Positives = 29/46 (63%), Gaps = 1/46 (2%)
Query: 26 NEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHI 71
NE + +S+ ++ +I + W+++SS + L+++ ++ ++ L H+
Sbjct: 244 NENRMEESKALFRTIITYPWFQNSS-VILFLNKKDLLEDKILYSHL 288
>AB209435-1|BAD92672.1| 357|Homo sapiens Guanine nucleotide-binding
protein G, alpha subunit variant protein.
Length = 357
Score = 29.9 bits (64), Expect = 6.0
Identities = 10/46 (21%), Positives = 29/46 (63%), Gaps = 1/46 (2%)
Query: 26 NEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHI 71
NE + +S+ ++ +I + W+++SS + L+++ ++ ++ L H+
Sbjct: 242 NENRMEESKALFRTIITYPWFQNSS-VILFLNKKDLLEDKILYSHL 286
>U43083-1|AAB06875.1| 359|Homo sapiens G alpha-q protein.
Length = 359
Score = 29.5 bits (63), Expect = 8.0
Identities = 12/60 (20%), Positives = 34/60 (56%), Gaps = 6/60 (10%)
Query: 26 NEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQARGAAAFVPQYAG 85
NE + +S+ ++ +I + W+++SS + L+++ ++ ++ + H+ + P+Y G
Sbjct: 244 NENRMEESKALFRTIITYPWFQNSS-VILFLNKKDLLEEKIMYSHL-----VDYFPEYDG 297
>U40038-1|AAC50363.1| 359|Homo sapiens GTP-binding protein alpha q
subunit protein.
Length = 359
Score = 29.5 bits (63), Expect = 8.0
Identities = 12/60 (20%), Positives = 34/60 (56%), Gaps = 6/60 (10%)
Query: 26 NEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQARGAAAFVPQYAG 85
NE + +S+ ++ +I + W+++SS + L+++ ++ ++ + H+ + P+Y G
Sbjct: 244 NENRMEESKALFRTIITYPWFQNSS-VILFLNKKDLLEEKIMYSHL-----VDYFPEYDG 297
>L76256-1|AAB39498.1| 359|Homo sapiens G alpha q protein.
Length = 359
Score = 29.5 bits (63), Expect = 8.0
Identities = 12/60 (20%), Positives = 34/60 (56%), Gaps = 6/60 (10%)
Query: 26 NEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQARGAAAFVPQYAG 85
NE + +S+ ++ +I + W+++SS + L+++ ++ ++ + H+ + P+Y G
Sbjct: 244 NENRMEESKALFRTIITYPWFQNSS-VILFLNKKDLLEEKIMYSHL-----VDYFPEYDG 297
>L40629-1|AAA99950.1| 94|Homo sapiens GAQ protein.
Length = 94
Score = 29.5 bits (63), Expect = 8.0
Identities = 12/60 (20%), Positives = 34/60 (56%), Gaps = 6/60 (10%)
Query: 26 NEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQARGAAAFVPQYAG 85
NE + +S+ ++ +I + W+++SS + L+++ ++ ++ + H+ + P+Y G
Sbjct: 1 NENRMEESKALFRTIITYPWFQNSS-VILFLNKKDLLEEKIMYSHL-----VDYFPEYDG 54
>BX537685-1|CAD97811.1| 520|Homo sapiens hypothetical protein
protein.
Length = 520
Score = 29.5 bits (63), Expect = 8.0
Identities = 18/66 (27%), Positives = 33/66 (50%), Gaps = 5/66 (7%)
Query: 7 NPAKALLRNEIAAKIAALTNEEKKR-QSQIVYEKVINHSWYKSSSRIALYMSTENEIDTA 65
+PA LL +++ K NE+K +S Y + IN +W K + + + ++ T
Sbjct: 208 SPASRLLLDQVGMK----ENEDKYMCESSGFYPEAINITWEKQTQKFPHPIEISEDVITG 263
Query: 66 PLIKHI 71
P IK++
Sbjct: 264 PTIKNM 269
>BC075097-1|AAH75097.1| 359|Homo sapiens guanine nucleotide binding
protein (G protein), q polypeptide protein.
Length = 359
Score = 29.5 bits (63), Expect = 8.0
Identities = 12/60 (20%), Positives = 34/60 (56%), Gaps = 6/60 (10%)
Query: 26 NEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQARGAAAFVPQYAG 85
NE + +S+ ++ +I + W+++SS + L+++ ++ ++ + H+ + P+Y G
Sbjct: 244 NENRMEESKALFRTIITYPWFQNSS-VILFLNKKDLLEEKIMYSHL-----VDYFPEYDG 297
>BC075096-1|AAH75096.1| 359|Homo sapiens guanine nucleotide binding
protein (G protein), q polypeptide protein.
Length = 359
Score = 29.5 bits (63), Expect = 8.0
Identities = 12/60 (20%), Positives = 34/60 (56%), Gaps = 6/60 (10%)
Query: 26 NEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQARGAAAFVPQYAG 85
NE + +S+ ++ +I + W+++SS + L+++ ++ ++ + H+ + P+Y G
Sbjct: 244 NENRMEESKALFRTIITYPWFQNSS-VILFLNKKDLLEEKIMYSHL-----VDYFPEYDG 297
>BC069520-1|AAH69520.1| 359|Homo sapiens guanine nucleotide binding
protein (G protein), q polypeptide protein.
Length = 359
Score = 29.5 bits (63), Expect = 8.0
Identities = 12/60 (20%), Positives = 34/60 (56%), Gaps = 6/60 (10%)
Query: 26 NEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQARGAAAFVPQYAG 85
NE + +S+ ++ +I + W+++SS + L+++ ++ ++ + H+ + P+Y G
Sbjct: 244 NENRMEESKALFRTIITYPWFQNSS-VILFLNKKDLLEEKIMYSHL-----VDYFPEYDG 297
>BC067850-1|AAH67850.1| 359|Homo sapiens guanine nucleotide binding
protein (G protein), q polypeptide protein.
Length = 359
Score = 29.5 bits (63), Expect = 8.0
Identities = 12/60 (20%), Positives = 34/60 (56%), Gaps = 6/60 (10%)
Query: 26 NEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQARGAAAFVPQYAG 85
NE + +S+ ++ +I + W+++SS + L+++ ++ ++ + H+ + P+Y G
Sbjct: 244 NENRMEESKALFRTIITYPWFQNSS-VILFLNKKDLLEEKIMYSHL-----VDYFPEYDG 297
>BC057777-1|AAH57777.1| 359|Homo sapiens guanine nucleotide binding
protein (G protein), q polypeptide protein.
Length = 359
Score = 29.5 bits (63), Expect = 8.0
Identities = 12/60 (20%), Positives = 34/60 (56%), Gaps = 6/60 (10%)
Query: 26 NEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQARGAAAFVPQYAG 85
NE + +S+ ++ +I + W+++SS + L+++ ++ ++ + H+ + P+Y G
Sbjct: 244 NENRMEESKALFRTIITYPWFQNSS-VILFLNKKDLLEEKIMYSHL-----VDYFPEYDG 297
>AL355535-2|CAI14669.1| 359|Homo sapiens guanine nucleotide binding
protein (G protein), qc acid transporter 5) protein.
Length = 359
Score = 29.5 bits (63), Expect = 8.0
Identities = 12/60 (20%), Positives = 34/60 (56%), Gaps = 6/60 (10%)
Query: 26 NEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQARGAAAFVPQYAG 85
NE + +S+ ++ +I + W+++SS + L+++ ++ ++ + H+ + P+Y G
Sbjct: 244 NENRMEESKALFRTIITYPWFQNSS-VILFLNKKDLLEEKIMYSHL-----VDYFPEYDG 297
>AL160278-2|CAI15999.1| 359|Homo sapiens guanine nucleotide binding
protein (G protein), qnit G1 protein.
Length = 359
Score = 29.5 bits (63), Expect = 8.0
Identities = 12/60 (20%), Positives = 34/60 (56%), Gaps = 6/60 (10%)
Query: 26 NEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQARGAAAFVPQYAG 85
NE + +S+ ++ +I + W+++SS + L+++ ++ ++ + H+ + P+Y G
Sbjct: 244 NENRMEESKALFRTIITYPWFQNSS-VILFLNKKDLLEEKIMYSHL-----VDYFPEYDG 297
>AL160268-2|CAI12198.1| 359|Homo sapiens guanine nucleotide binding
protein (G protein), qontaining 2 (S. cerevisiae)
protein.
Length = 359
Score = 29.5 bits (63), Expect = 8.0
Identities = 12/60 (20%), Positives = 34/60 (56%), Gaps = 6/60 (10%)
Query: 26 NEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQARGAAAFVPQYAG 85
NE + +S+ ++ +I + W+++SS + L+++ ++ ++ + H+ + P+Y G
Sbjct: 244 NENRMEESKALFRTIITYPWFQNSS-VILFLNKKDLLEEKIMYSHL-----VDYFPEYDG 297
>AF493896-1|AAM12610.1| 359|Homo sapiens guanine nucleotide binding
protein alpha q protein.
Length = 359
Score = 29.5 bits (63), Expect = 8.0
Identities = 12/60 (20%), Positives = 34/60 (56%), Gaps = 6/60 (10%)
Query: 26 NEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQARGAAAFVPQYAG 85
NE + +S+ ++ +I + W+++SS + L+++ ++ ++ + H+ + P+Y G
Sbjct: 244 NENRMEESKALFRTIITYPWFQNSS-VILFLNKKDLLEEKIMYSHL-----VDYFPEYDG 297
>AF329284-1|AAG61117.1| 359|Homo sapiens G alpha q protein protein.
Length = 359
Score = 29.5 bits (63), Expect = 8.0
Identities = 12/60 (20%), Positives = 34/60 (56%), Gaps = 6/60 (10%)
Query: 26 NEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQARGAAAFVPQYAG 85
NE + +S+ ++ +I + W+++SS + L+++ ++ ++ + H+ + P+Y G
Sbjct: 244 NENRMEESKALFRTIITYPWFQNSS-VILFLNKKDLLEEKIMYSHL-----VDYFPEYDG 297
>AF011496-1|AAB64301.1| 359|Homo sapiens GTP-binding protein alpha
q protein.
Length = 359
Score = 29.5 bits (63), Expect = 8.0
Identities = 12/60 (20%), Positives = 34/60 (56%), Gaps = 6/60 (10%)
Query: 26 NEEKKRQSQIVYEKVINHSWYKSSSRIALYMSTENEIDTAPLIKHIQARGAAAFVPQYAG 85
NE + +S+ ++ +I + W+++SS + L+++ ++ ++ + H+ + P+Y G
Sbjct: 244 NENRMEESKALFRTIITYPWFQNSS-VILFLNKKDLLEEKIMYSHL-----VDYFPEYDG 297
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.315 0.132 0.376
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 28,250,511
Number of Sequences: 224733
Number of extensions: 1136585
Number of successful extensions: 1896
Number of sequences better than 10.0: 51
Number of HSP's better than 10.0 without gapping: 14
Number of HSP's successfully gapped in prelim test: 37
Number of HSP's that attempted gapping in prelim test: 1873
Number of HSP's gapped (non-prelim): 60
length of query: 196
length of database: 73,234,838
effective HSP length: 86
effective length of query: 110
effective length of database: 53,907,800
effective search space: 5929858000
effective search space used: 5929858000
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.6 bits)
S2: 63 (29.5 bits)
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