Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA002069-TA|BGIBMGA002069-PA|IPR001452|Src homology-3,
IPR000980|SH2 motif, IPR001245|Tyrosine protein kinase,
IPR011009|Protein kinase-like, IPR000719|Protein kinase,
IPR008266|Tyrosine protein kinase, active site, IPR001720|PI3 kinase,
P85 regulatory subunit
(473 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X16416-1|CAA34438.1| 1130|Homo sapiens protein ( Human c-abl mRN... 686 0.0
U07563-2|AAB60394.1| 1130|Homo sapiens proto-oncogene tyrosine-p... 686 0.0
U07563-1|AAB60393.1| 1149|Homo sapiens proto-oncogene tyrosine-p... 686 0.0
DQ145721-1|AAZ38718.1| 1149|Homo sapiens v-abl Abelson murine le... 686 0.0
BC117451-1|AAI17452.1| 1149|Homo sapiens v-abl Abelson murine le... 686 0.0
AL359092-11|CAM45752.1| 1149|Homo sapiens v-abl Abelson murine l... 686 0.0
AL161733-3|CAM45756.1| 1149|Homo sapiens v-abl Abelson murine le... 686 0.0
AL161733-1|CAM45754.1| 1130|Homo sapiens v-abl Abelson murine le... 686 0.0
AB209456-1|BAD92693.1| 1167|Homo sapiens v-abl Abelson murine le... 686 0.0
M14752-1|AAA51561.1| 1130|Homo sapiens ABL1 protein. 679 0.0
M35296-1|AAA35553.1| 1182|Homo sapiens protein ( Human tyrosine ... 658 0.0
DQ009672-1|AAY16984.1| 1182|Homo sapiens v-abl Abelson murine le... 658 0.0
BX538317-1|CAD98092.1| 1092|Homo sapiens hypothetical protein pr... 658 0.0
BC065912-1|AAH65912.1| 1167|Homo sapiens ABL2 protein protein. 658 0.0
AL512326-6|CAI13570.1| 1182|Homo sapiens v-abl Abelson murine le... 658 0.0
AL512326-2|CAI13566.1| 1064|Homo sapiens v-abl Abelson murine le... 658 0.0
AL359179-2|CAI15585.1| 1182|Homo sapiens v-abl Abelson murine le... 658 0.0
AL359179-1|CAI15584.1| 1064|Homo sapiens v-abl Abelson murine le... 658 0.0
AL139132-5|CAH70925.1| 1182|Homo sapiens v-abl Abelson murine le... 658 0.0
AL139132-1|CAH70921.1| 1064|Homo sapiens v-abl Abelson murine le... 658 0.0
AB209642-1|BAD92879.1| 949|Homo sapiens Proto-oncogene tyrosine... 354 4e-97
Z97989-4|CAI22300.1| 537|Homo sapiens FYN oncogene related to S... 353 1e-96
M14333-1|AAC08285.1| 537|Homo sapiens protein ( Homo sapiens c-... 353 1e-96
M14676-1|AAA36615.1| 537|Homo sapiens protein ( Human src-like ... 352 1e-96
K03218-1|AAA60584.1| 536|Homo sapiens SRC protein. 347 7e-95
BC051270-1|AAH51270.2| 536|Homo sapiens v-src sarcoma (Schmidt-... 347 7e-95
BC011566-1|AAH11566.1| 536|Homo sapiens SRC protein protein. 347 7e-95
AL133293-1|CAC34523.1| 536|Homo sapiens v-src sarcoma (Schmidt-... 347 7e-95
Z97989-5|CAI22301.1| 534|Homo sapiens FYN oncogene related to S... 346 9e-95
S74774-1|AAB33113.2| 534|Homo sapiens tyrosine kinase p59fyn(T)... 345 2e-94
M19722-1|AAA52451.1| 529|Homo sapiens FGR protein. 343 1e-93
BC064382-1|AAH64382.1| 529|Homo sapiens Gardner-Rasheed feline ... 343 1e-93
AL031729-3|CAB62998.1| 529|Homo sapiens Gardner-Rasheed feline ... 343 1e-93
M15990-1|AAA35735.1| 543|Homo sapiens protein ( Human c-yes-1 m... 342 1e-93
BC048960-1|AAH48960.1| 543|Homo sapiens v-yes-1 Yamaguchi sarco... 342 1e-93
AL133293-2|CAC10573.1| 542|Homo sapiens v-src sarcoma (Schmidt-... 341 3e-93
U22322-1|AAC50116.1| 505|Homo sapiens Rak protein. 337 5e-92
U00803-1|AAA18284.1| 505|Homo sapiens SRC-like tyrosine kinase ... 336 7e-92
BC012916-1|AAH12916.1| 505|Homo sapiens fyn-related kinase prot... 336 7e-92
AL357141-2|CAI16469.1| 505|Homo sapiens fyn-related kinase prot... 336 7e-92
AL121963-8|CAB87592.2| 505|Homo sapiens fyn-related kinase prot... 336 7e-92
AL353092-1|CAI19695.1| 504|Homo sapiens hemopoietic cell kinase... 332 2e-90
AL049539-2|CAI22967.1| 504|Homo sapiens hemopoietic cell kinase... 332 2e-90
M16592-1|AAA52644.1| 505|Homo sapiens HCK protein. 331 3e-90
M16591-1|AAA52643.1| 505|Homo sapiens HCK protein. 331 3e-90
BC114463-1|AAI14464.2| 526|Homo sapiens hemopoietic cell kinase... 331 3e-90
BC108931-1|AAI08932.2| 526|Homo sapiens hemopoietic cell kinase... 331 3e-90
BC108930-1|AAI08931.2| 526|Homo sapiens hemopoietic cell kinase... 331 3e-90
BC094847-1|AAH94847.2| 526|Homo sapiens hemopoietic cell kinase... 331 3e-90
BC014435-1|AAH14435.2| 526|Homo sapiens hemopoietic cell kinase... 331 3e-90
AL353092-2|CAI19694.1| 505|Homo sapiens hemopoietic cell kinase... 331 3e-90
AL049539-1|CAI22966.1| 505|Homo sapiens hemopoietic cell kinase... 331 3e-90
AM491362-1|CAM33012.1| 585|Homo sapiens bcr-abl1 e6a2 chimeric ... 330 5e-90
BC113854-1|AAI13855.2| 504|Homo sapiens HCK protein protein. 330 8e-90
AM491363-1|CAM33013.1| 498|Homo sapiens bcr-abl1 e19a2 chimeric... 329 1e-89
AK026432-1|BAB15482.1| 505|Homo sapiens protein ( Homo sapiens ... 326 1e-88
U07236-1|AAA18225.1| 512|Homo sapiens lymphocyte-specific prote... 321 3e-87
X14055-1|CAA32211.1| 509|Homo sapiens protein ( Human lymphocyt... 320 9e-87
AL121991-2|CAI22320.1| 496|Homo sapiens lymphocyte-specific pro... 320 9e-87
AF228313-1|AAF34794.1| 496|Homo sapiens tyrosine kinase LCK pro... 320 9e-87
M79321-1|AAB50019.1| 491|Homo sapiens Lyn B protein protein. 319 1e-86
M16038-1|AAA59540.1| 512|Homo sapiens LYN protein. 319 1e-86
BC126458-1|AAI26459.1| 512|Homo sapiens LYN protein protein. 319 1e-86
BC126456-1|AAI26457.1| 512|Homo sapiens LYN protein protein. 319 1e-86
BC075002-1|AAH75002.1| 512|Homo sapiens v-yes-1 Yamaguchi sarco... 319 1e-86
BC075001-1|AAH75001.1| 512|Homo sapiens v-yes-1 Yamaguchi sarco... 319 1e-86
BC068551-1|AAH68551.1| 582|Homo sapiens LYN protein protein. 319 1e-86
BC059394-1|AAH59394.1| 582|Homo sapiens LYN protein protein. 319 1e-86
BC032413-1|AAH32413.1| 505|Homo sapiens B lymphoid tyrosine kin... 318 2e-86
BC018703-1|AAH18703.1| 599|Homo sapiens Unknown (protein for IM... 318 2e-86
BC007371-1|AAH07371.1| 505|Homo sapiens B lymphoid tyrosine kin... 318 2e-86
Z33998-1|CAA83965.1| 505|Homo sapiens Protein-Tyrosine Kinase p... 318 4e-86
X13529-1|CAA31884.1| 509|Homo sapiens protein ( Human lck mRNA ... 317 5e-86
S76617-1|AAB33265.1| 505|Homo sapiens blk protein. 317 5e-86
M36881-1|AAA59502.1| 509|Homo sapiens lymphocyte-specific prote... 315 3e-85
BC101713-1|AAI01714.1| 631|Homo sapiens tec protein tyrosine ki... 315 3e-85
BC101711-1|AAI01712.1| 631|Homo sapiens tec protein tyrosine ki... 315 3e-85
D29767-1|BAA06171.1| 631|Homo sapiens Tec protein-tyrosine kina... 314 3e-85
AJ131467-1|CAA10377.1| 307|Homo sapiens BCR/ABL chimeric fusion... 313 1e-84
AJ131466-1|CAA10376.1| 332|Homo sapiens BCR/ABL (major breakpoi... 313 1e-84
AF113911-1|AAD04633.1| 359|Homo sapiens BCR-ABL minor breakpoin... 313 1e-84
X58957-1|CAA41728.1| 659|Homo sapiens agammaglobulinaemia tyros... 301 2e-81
U78027-4|AAB64205.1| 659|Homo sapiens Bruton's tyrosine kinase ... 301 2e-81
U10087-1|AAB60639.1| 659|Homo sapiens Bruton agammaglobulinemia... 301 2e-81
L31572-1|AAA61479.1| 659|Homo sapiens Bruton agammaglobulinemia... 301 2e-81
BC109080-1|AAI09081.1| 659|Homo sapiens Bruton agammaglobulinem... 301 2e-81
BC109079-1|AAI09080.1| 659|Homo sapiens Bruton agammaglobulinem... 301 2e-81
AL035422-3|CAB55876.1| 659|Homo sapiens Bruton agammaglobulinem... 301 2e-81
X05027-1|CAA28691.1| 507|Homo sapiens protein ( Human T cell-sp... 298 2e-80
U13433-1|AAC51347.1| 657|Homo sapiens Bruton's agammaglobulinem... 295 2e-79
L27071-1|AAA74557.1| 527|Homo sapiens tyrosine kinase protein. 289 2e-77
U34379-1|AAB60412.1| 527|Homo sapiens tyrosine kinase protein. 287 4e-77
L10717-1|AAA36748.1| 620|Homo sapiens tyrosine kinase protein. 287 8e-77
D13720-1|BAA02873.1| 620|Homo sapiens ITK protein. 287 8e-77
BC109078-1|AAI09079.1| 620|Homo sapiens IL2-inducible T-cell ki... 287 8e-77
BC109077-1|AAI09078.1| 620|Homo sapiens IL2-inducible T-cell ki... 287 8e-77
Z97989-6|CAI22299.1| 485|Homo sapiens FYN oncogene related to S... 285 2e-76
AL121829-14|CAC15526.1| 488|Homo sapiens protein ( Human DNA se... 285 3e-76
X74765-1|CAB58562.1| 450|Homo sapiens protein tyrosine kinase p... 284 4e-76
X60114-1|CAA42713.1| 450|Homo sapiens put. cytoplasmic tyrosine... 284 4e-76
X59932-1|CAA42556.1| 450|Homo sapiens c-src-kinase protein. 284 4e-76
S65186-1|AAB28072.2| 620|Homo sapiens EMT protein. 284 4e-76
DQ075211-1|AAY57329.1| 450|Homo sapiens c-src tyrosine kinase p... 284 4e-76
CR541960-1|CAG46758.1| 450|Homo sapiens CSK protein. 284 4e-76
BC106073-1|AAI06074.1| 450|Homo sapiens c-src tyrosine kinase p... 284 4e-76
BC104875-1|AAI04876.1| 450|Homo sapiens c-src tyrosine kinase p... 284 4e-76
BC104847-1|AAI04848.1| 450|Homo sapiens c-src tyrosine kinase p... 284 4e-76
AK223626-1|BAD97346.1| 449|Homo sapiens c-src tyrosine kinase v... 284 5e-76
AM491361-1|CAM33011.1| 313|Homo sapiens bcr-abl1 e1a3 chimeric ... 280 7e-75
AM491359-1|CAM33009.1| 235|Homo sapiens bcr-abl1 e13a3 chimeric... 280 7e-75
AM491360-1|CAM33010.1| 260|Homo sapiens bcr-abl1 e14a3 chimeric... 277 6e-74
X83107-1|CAA58169.1| 675|Homo sapiens bmx protein. 270 7e-72
BC016652-1|AAH16652.1| 675|Homo sapiens BMX non-receptor tyrosi... 270 7e-72
X78549-1|CAA55295.1| 451|Homo sapiens tyrosine kinase protein. 268 4e-71
U61412-1|AAC34935.1| 451|Homo sapiens non-receptor type protein... 268 4e-71
BC035843-1|AAH35843.1| 451|Homo sapiens PTK6 protein tyrosine k... 268 4e-71
AL121829-13|CAC15525.1| 451|Homo sapiens Ptk6 protein. 268 4e-71
AF045459-1|AAC08966.1| 697|Homo sapiens Etk/Bmx cytosolic tyros... 267 7e-71
X02647-1|CAA26485.1| 351|Homo sapiens c-src protein. 263 1e-69
X58741-1|CAA41565.2| 348|Homo sapiens tyrosine kinase protein. 259 2e-68
M12724-1|AAA52762.1| 306|Homo sapiens FGR protein. 246 1e-64
AM051276-1|CAJ19682.1| 319|Homo sapiens dominant-negative kinas... 245 2e-64
J03358-1|AAA61190.1| 822|Homo sapiens FER protein. 240 7e-63
X52192-1|CAA36438.1| 822|Homo sapiens c-fes protein. 231 4e-60
AY513656-1|AAS82868.1| 764|Homo sapiens proto-oncogene c-fes va... 231 4e-60
X06292-1|CAA29619.1| 822|Homo sapiens NCP92 protein. 230 7e-60
BC035357-1|AAH35357.1| 822|Homo sapiens feline sarcoma oncogene... 230 7e-60
X77278-1|CAA54493.1| 507|Homo sapiens HYL tyrosine kinase protein. 229 1e-59
S75164-1|AAC60645.1| 507|Homo sapiens megakaryocyte-associated ... 229 1e-59
BC003109-1|AAH03109.1| 507|Homo sapiens megakaryocyte-associate... 229 1e-59
BC000114-1|AAH00114.1| 507|Homo sapiens megakaryocyte-associate... 229 1e-59
AC005777-1|AAC62843.1| 507|Homo sapiens MATK_HUMAN protein. 229 1e-59
L18974-1|AAA16703.1| 527|Homo sapiens tyrosine kinase protein. 225 2e-58
S71669-1|AAB30995.1| 465|Homo sapiens lsk protein. 223 1e-57
BC032496-1|AAH32496.1| 482|Homo sapiens FYN oncogene related to... 212 3e-54
AY513657-1|AAS82869.1| 752|Homo sapiens proto-oncogene c-fes va... 210 6e-54
AY513654-1|AAS82866.1| 694|Homo sapiens proto-oncogene c-fes va... 210 6e-54
AK024281-1|BAB14871.1| 251|Homo sapiens protein ( Homo sapiens ... 208 2e-53
BC013200-1|AAH13200.1| 539|Homo sapiens LCK protein protein. 206 1e-52
AL121991-3|CAI22321.1| 526|Homo sapiens lymphocyte-specific pro... 206 1e-52
AJ865079-1|CAI23831.1| 516|Homo sapiens proto-oncogene tyrosine... 200 1e-50
L40636-1|AAB08520.1| 984|Homo sapiens protein tyrosine kinase p... 192 2e-48
BC111744-1|AAI11745.1| 984|Homo sapiens EPH receptor B1 protein. 191 5e-48
AF037332-1|AAD02031.1| 973|Homo sapiens Eph-like receptor tyros... 191 5e-48
L36643-1|AAA74244.1| 970|Homo sapiens receptor protein-tyrosine... 190 7e-48
AF037331-1|AAD02030.1| 984|Homo sapiens Eph-like receptor tyros... 189 2e-47
L41939-1|AAA99310.1| 987|Homo sapiens protein-tyrosine kinase p... 188 4e-47
D37827-1|BAA07073.1| 478|Homo sapiens large erk/cek5 tyrosine k... 188 4e-47
D31661-1|BAA06506.1| 981|Homo sapiens tyrosine kinase precursor... 188 4e-47
AL512444-4|CAI16429.1| 1055|Homo sapiens EPH receptor B2 protein. 188 4e-47
AL512444-3|CAI16428.1| 987|Homo sapiens EPH receptor B2 protein. 188 4e-47
AL512444-2|CAI16430.2| 986|Homo sapiens EPH receptor B2 protein. 188 4e-47
AL512444-1|CAI16427.1| 946|Homo sapiens EPH receptor B2 protein. 188 4e-47
AL158086-8|CAI22898.1| 1055|Homo sapiens EPH receptor B2 protein. 188 4e-47
AL158086-7|CAI22899.2| 986|Homo sapiens EPH receptor B2 protein. 188 4e-47
AL158086-6|CAI22897.1| 987|Homo sapiens EPH receptor B2 protein. 188 4e-47
AL035704-4|CAI22646.1| 1055|Homo sapiens EPH receptor B2 protein. 188 4e-47
AL035704-3|CAI22645.1| 987|Homo sapiens EPH receptor B2 protein. 188 4e-47
AL035704-2|CAI22647.2| 986|Homo sapiens EPH receptor B2 protein. 188 4e-47
AL035704-1|CAI22644.1| 946|Homo sapiens EPH receptor B2 protein. 188 4e-47
AF025304-1|AAB94602.1| 1055|Homo sapiens protein-tyrosine kinase... 188 4e-47
AB210018-1|BAE06100.1| 1004|Homo sapiens EPHB2 variant protein p... 188 4e-47
Z27409-1|CAA81796.1| 691|Homo sapiens receptor tyrosine kinase ... 186 1e-46
BC130291-1|AAI30292.1| 976|Homo sapiens EPH receptor A1 protein. 186 1e-46
AF101171-1|AAD43440.1| 976|Homo sapiens receptor tyrosine kinas... 186 1e-46
AC092214-2|AAS07458.1| 976|Homo sapiens unknown protein. 186 1e-46
X75208-1|CAA53021.1| 998|Homo sapiens protein tyrosine kinase-r... 186 2e-46
M83941-1|AAA58633.1| 983|Homo sapiens receptor protein kinase p... 186 2e-46
BC063282-1|AAH63282.1| 983|Homo sapiens EPH receptor A3 protein. 186 2e-46
BC052968-1|AAH52968.1| 998|Homo sapiens EPH receptor B3 protein. 186 2e-46
AF213459-1|AAG43576.1| 983|Homo sapiens ephrin receptor EPHA3 c... 186 2e-46
U23852-1|AAC50287.1| 363|Homo sapiens p56lck protein. 185 3e-46
M18391-1|AAA36747.1| 984|Homo sapiens protein ( Human tyrosine ... 184 8e-46
L36645-1|AAA74246.1| 986|Homo sapiens receptor protein-tyrosine... 183 1e-45
BC105002-1|AAI05003.1| 986|Homo sapiens ephrin receptor EphA4 p... 183 1e-45
BC105000-1|AAI05001.1| 986|Homo sapiens EPH receptor A4 protein. 183 1e-45
BC026327-1|AAH26327.1| 949|Homo sapiens EPHA4 protein protein. 183 1e-45
AC010899-2|AAY24284.1| 711|Homo sapiens unknown protein. 183 1e-45
Y13901-1|CAA74200.1| 802|Homo sapiens fibroblast growth factor ... 183 1e-45
X57205-1|CAA40490.1| 802|Homo sapiens fibroblast growth factor ... 183 1e-45
L03840-1|AAB59389.1| 802|Homo sapiens fibroblast growth factor ... 183 1e-45
EF571596-1|ABQ01235.1| 802|Homo sapiens fibroblast growth facto... 183 1e-45
BC011847-1|AAH11847.1| 802|Homo sapiens fibroblast growth facto... 183 1e-45
AF487555-1|AAM13666.1| 802|Homo sapiens fibroblast growth facto... 183 1e-45
AF359246-1|AAK51435.1| 592|Homo sapiens fibroblast growth facto... 183 1e-45
AF202063-1|AAF27432.1| 762|Homo sapiens fibroblast growth facto... 183 1e-45
AB209631-1|BAD92868.1| 1034|Homo sapiens Fibroblast growth facto... 183 1e-45
L08961-1|AAC41766.1| 600|Homo sapiens tyrosine kinase protein. 180 7e-45
AF041811-1|AAC12728.2| 408|Homo sapiens ETS related protein-gro... 180 7e-45
X57019-1|CAA40338.1| 894|Homo sapiens protein ( H.sapiens mRNA ... 180 1e-44
U07695-1|AAA20598.1| 987|Homo sapiens tyrosine kinase protein. 180 1e-44
S65125-1|AAB20305.1| 894|Homo sapiens UFO protein. 180 1e-44
BC052804-1|AAH52804.1| 987|Homo sapiens EPH receptor B4 protein. 180 1e-44
BC004264-1|AAH04264.1| 845|Homo sapiens EPHB4 protein protein. 180 1e-44
AY056048-1|AAL14195.1| 935|Homo sapiens receptor protein tyrosi... 180 1e-44
AY056047-1|AAL14194.1| 987|Homo sapiens receptor protein tyrosi... 180 1e-44
AL031729-2|CAI19617.1| 313|Homo sapiens Gardner-Rasheed feline ... 180 1e-44
AF312032-8|AAK21010.1| 987|Homo sapiens ephrin type-B receptor ... 180 1e-44
AB209644-1|BAD92881.1| 986|Homo sapiens ephrin receptor EphB4 p... 180 1e-44
BC032229-1|AAH32229.1| 894|Homo sapiens AXL receptor tyrosine k... 180 1e-44
AF125808-1|AAF19762.1| 318|Homo sapiens ETS related protein-neu... 180 1e-44
M76125-1|AAA61243.1| 885|Homo sapiens tyrosine kinase receptor ... 179 2e-44
AK222718-1|BAD96438.1| 820|Homo sapiens fibroblast growth facto... 179 2e-44
Z71929-1|CAA96492.1| 821|Homo sapiens FGFR2 protein. 179 2e-44
Y00665-1|CAA68679.1| 622|Homo sapiens tyrosine kinase protein. 179 2e-44
X66945-1|CAA47375.1| 822|Homo sapiens fibroblast growth factor ... 179 2e-44
X57122-1|CAA40404.1| 731|Homo sapiens Fibroblast Growth Factor ... 179 2e-44
X57121-1|CAA40403.1| 822|Homo sapiens Fibroblast Growth Factor ... 179 2e-44
X57120-1|CAA40402.1| 820|Homo sapiens Fibroblast Growth Factor ... 179 2e-44
X57119-1|CAA40401.1| 733|Homo sapiens Fibroblast Growth Factor ... 179 2e-44
X56191-1|CAA39654.1| 769|Homo sapiens fibroblast growth factor ... 179 2e-44
X52833-1|CAA37015.1| 822|Homo sapiens protein ( Human flg mRNA ... 179 2e-44
X52832-1|CAA37014.1| 821|Homo sapiens protein ( Human bek mRNA ... 179 2e-44
X51803-1|CAA36101.1| 822|Homo sapiens protein ( Human mRNA for ... 179 2e-44
M97193-1|AAA52449.1| 822|Homo sapiens fibroblast growth factor ... 179 2e-44
M87771-1|AAA59471.1| 705|Homo sapiens fibroblast growth factor ... 179 2e-44
M87770-1|AAA59470.1| 821|Homo sapiens fibroblast growth factor ... 179 2e-44
M63887-1|AAA35958.1| 822|Homo sapiens heparin-binding growth fa... 179 2e-44
M60485-1|AAA35840.1| 820|Homo sapiens fibroblast growth factor ... 179 2e-44
M55614-1|AAA61188.1| 822|Homo sapiens TK14 protein protein. 179 2e-44
M35718-1|AAA36152.1| 682|Homo sapiens protein ( Human heparin-b... 179 2e-44
M34641-1|AAA35835.1| 820|Homo sapiens protein ( Human fibroblas... 179 2e-44
M34186-1|AAA35837.1| 731|Homo sapiens protein ( Human fibroblas... 179 2e-44
M34185-1|AAA35836.1| 733|Homo sapiens protein ( Human fibroblas... 179 2e-44
DQ493927-1|ABE96832.1| 785|Homo sapiens fibroblast growth facto... 179 2e-44
BC091494-1|AAH91494.1| 731|Homo sapiens fibroblast growth facto... 179 2e-44
BC039243-1|AAH39243.2| 704|Homo sapiens FGFR2 protein protein. 179 2e-44
BC018128-1|AAH18128.1| 820|Homo sapiens fibroblast growth facto... 179 2e-44
BC015035-1|AAH15035.1| 820|Homo sapiens FGFR1 protein protein. 179 2e-44
AY585209-1|AAS79322.1| 822|Homo sapiens fibroblast growth facto... 179 2e-44
AF487553-1|AAM74056.1| 822|Homo sapiens fibroblast growth facto... 179 2e-44
AF360695-4|AAK94208.1| 766|Homo sapiens keratinocyte growth fac... 179 2e-44
AF360695-3|AAK94209.1| 785|Homo sapiens keratinocyte growth fac... 179 2e-44
AF360695-2|AAK94205.1| 819|Homo sapiens keratinocyte growth fac... 179 2e-44
AF360695-1|AAK94206.1| 820|Homo sapiens keratinocyte growth fac... 179 2e-44
AF097353-2|AAD31561.1| 554|Homo sapiens fibroblast growth facto... 179 2e-44
AF097353-1|AAD31560.1| 555|Homo sapiens fibroblast growth recep... 179 2e-44
AB208919-1|BAD92156.1| 814|Homo sapiens fibroblast growth facto... 179 2e-44
AB084153-1|BAC45037.1| 709|Homo sapiens isoform of FGFR2 protein. 179 2e-44
X95425-1|CAA64700.1| 1037|Homo sapiens EHK-1 receptor tyrosine k... 178 3e-44
U05012-1|AAA75374.1| 825|Homo sapiens TrkC protein. 178 3e-44
M37722-1|AAA75007.1| 731|Homo sapiens basic fibroblast growth f... 178 3e-44
L36644-1|AAA74245.1| 991|Homo sapiens receptor protein-tyrosine... 178 3e-44
AB209375-1|BAD92612.1| 1017|Homo sapiens ephrin receptor EphA5 i... 178 3e-44
X04434-1|CAA28030.1| 1367|Homo sapiens IGF-I receptor protein. 177 7e-44
U12140-1|AAC51371.1| 822|Homo sapiens tyrosine kinase receptor ... 177 7e-44
S76473-1|AAB33109.1| 822|Homo sapiens trkB protein. 177 7e-44
L07868-1|AAB59446.1| 1308|Homo sapiens receptor tyrosine kinase ... 177 7e-44
BC114918-1|AAI14919.1| 823|Homo sapiens MERTK protein protein. 177 7e-44
BC114917-1|AAI14918.1| 823|Homo sapiens MERTK protein protein. 177 7e-44
BC113612-1|AAI13613.1| 1367|Homo sapiens insulin-like growth fac... 177 7e-44
BC113610-1|AAI13611.1| 1367|Homo sapiens insulin-like growth fac... 177 7e-44
BC112199-1|AAI12200.1| 1308|Homo sapiens v-erb-a erythroblastic ... 177 7e-44
AY332722-1|AAP81165.1| 1367|Homo sapiens insulin-like growth fac... 177 7e-44
AL596132-4|CAH72315.1| 822|Homo sapiens neurotrophic tyrosine k... 177 7e-44
AL596132-3|CAH72316.1| 838|Homo sapiens neurotrophic tyrosine k... 177 7e-44
AL445532-2|CAH71817.1| 822|Homo sapiens neurotrophic tyrosine k... 177 7e-44
AL445532-1|CAH71816.1| 838|Homo sapiens neurotrophic tyrosine k... 177 7e-44
AL390777-4|CAH72196.1| 822|Homo sapiens neurotrophic tyrosine k... 177 7e-44
AL390777-3|CAH72195.1| 838|Homo sapiens neurotrophic tyrosine k... 177 7e-44
AF410899-1|AAL67965.1| 838|Homo sapiens neurotrophin receptor t... 177 7e-44
AF400441-1|AAK92490.1| 822|Homo sapiens neurotrophic tyrosine k... 177 7e-44
AF260529-1|AAG33129.1| 978|Homo sapiens MER receptor tyrosine k... 177 7e-44
AC093675-1|AAY24213.1| 567|Homo sapiens unknown protein. 177 7e-44
AB209697-1|BAD92934.1| 892|Homo sapiens v-erb-a erythroblastic ... 177 7e-44
M59371-1|AAA53375.1| 976|Homo sapiens protein-tyrosine kinase p... 177 9e-44
BC037166-1|AAH37166.1| 976|Homo sapiens EPH receptor A2 protein. 177 9e-44
AL451042-1|CAH71943.1| 976|Homo sapiens EPH receptor A2 protein. 177 9e-44
L36642-1|AAA74243.1| 998|Homo sapiens receptor protein-tyrosine... 176 2e-43
L13616-1|AAA58469.1| 1052|Homo sapiens focal adhesion kinase pro... 176 2e-43
BC126151-1|AAI26152.1| 998|Homo sapiens EPH receptor A7 protein. 176 2e-43
BC126125-1|AAI26126.1| 998|Homo sapiens EPH receptor A7 protein. 176 2e-43
BC035404-1|AAH35404.1| 1006|Homo sapiens PTK2 protein protein. 176 2e-43
BC028733-1|AAH28733.1| 680|Homo sapiens PTK2 protein protein. 176 2e-43
AL591036-1|CAH73650.1| 998|Homo sapiens EPH receptor A7 protein. 176 2e-43
AL354857-1|CAH72780.1| 998|Homo sapiens EPH receptor A7 protein. 176 2e-43
AL121966-2|CAI19722.1| 998|Homo sapiens EPH receptor A7 protein. 176 2e-43
AK094999-1|BAC04470.1| 720|Homo sapiens protein ( Homo sapiens ... 176 2e-43
AB209269-1|BAD92506.1| 1000|Homo sapiens ephrin receptor EphA7 v... 176 2e-43
AB209083-1|BAD92320.1| 1007|Homo sapiens PTK2 protein tyrosine k... 176 2e-43
AB209071-1|BAD92308.1| 975|Homo sapiens PTK2 protein tyrosine k... 176 2e-43
M80634-1|AAA36147.1| 822|Homo sapiens keratinocyte growth facto... 175 2e-43
M64347-1|AAA58470.1| 731|Homo sapiens fgflr protein. 175 2e-43
M58051-1|AAA52450.1| 806|Homo sapiens fibroblast growth factor ... 175 2e-43
D14717-1|BAA03537.1| 347|Homo sapiens large erk kinase protein. 175 2e-43
BC128610-1|AAI28611.1| 480|Homo sapiens FGFR3 protein protein. 175 2e-43
BC121175-1|AAI21176.1| 480|Homo sapiens FGFR3 protein protein. 175 2e-43
AY768549-1|AAU89726.1| 806|Homo sapiens fibroblast growth facto... 175 2e-43
AF487554-2|AAM22078.1| 769|Homo sapiens fibroblast growth facto... 175 2e-43
AF487554-1|AAM22079.1| 771|Homo sapiens fibroblast growth facto... 175 2e-43
AF245114-1|AAF63380.1| 694|Homo sapiens fibroblast growth facto... 175 2e-43
AB030078-1|BAA89301.1| 768|Homo sapiens K-sam-IIO3 protein. 175 2e-43
AB030077-1|BAA89300.1| 817|Homo sapiens K-sam-IIO2 protein. 175 2e-43
AB030076-1|BAA89299.1| 771|Homo sapiens K-sam-IIO1 protein. 175 2e-43
AB030075-1|BAA89298.1| 830|Homo sapiens K-sam-IIH3 protein. 175 2e-43
AB030074-1|BAA89297.1| 819|Homo sapiens K-sam-IIH2 protein. 175 2e-43
AB030073-1|BAA89296.1| 819|Homo sapiens K-sam-IIH1 protein. 175 2e-43
U08023-1|AAB60430.1| 999|Homo sapiens c-mer protein. 175 3e-43
BX537946-1|CAD97914.1| 969|Homo sapiens hypothetical protein pr... 175 3e-43
Z98880-3|CAI42375.1| 2341|Homo sapiens v-ros UR2 sarcoma virus o... 171 3e-42
Z98880-2|CAI42374.1| 2347|Homo sapiens v-ros UR2 sarcoma virus o... 171 3e-42
M34353-1|AAA60278.1| 2347|Homo sapiens ROS1 protein. 171 3e-42
M13880-1|AAA36580.1| 494|Homo sapiens protein ( Human mcf3 (rea... 171 3e-42
M13599-1|AAA60277.1| 471|Homo sapiens ROS1 protein. 171 3e-42
AL132671-5|CAI23378.1| 2347|Homo sapiens v-ros UR2 sarcoma virus... 171 3e-42
AL132671-4|CAI23379.1| 2341|Homo sapiens v-ros UR2 sarcoma virus... 171 3e-42
X62947-1|CAA44719.1| 503|Homo sapiens 55 kd protein protein. 171 6e-42
X06704-1|CAA29888.1| 439|Homo sapiens protein ( Human mRNA for ... 171 6e-42
X03541-1|CAA27243.1| 641|Homo sapiens protein ( Human mRNA of t... 171 6e-42
M23102-1|AAA36770.1| 790|Homo sapiens protein ( Human trk proto... 171 6e-42
L13738-1|AAA53570.2| 1036|Homo sapiens activated p21cdc42Hs kina... 171 6e-42
BC062580-1|AAH62580.1| 795|Homo sapiens NTRK1 protein protein. 171 6e-42
BC028164-1|AAH28164.1| 528|Homo sapiens TNK2 protein protein. 171 6e-42
AL158169-4|CAH70010.1| 790|Homo sapiens neurotrophic tyrosine k... 171 6e-42
AK131539-1|BAD18675.1| 1086|Homo sapiens protein ( Homo sapiens ... 171 6e-42
AB019488-1|BAA34355.1| 796|Homo sapiens TRKA protein. 171 6e-42
X85960-1|CAA59936.1| 591|Homo sapiens p68 TRK-T3 oncoprotein pr... 170 8e-42
M25946-1|AAA35697.1| 156|Homo sapiens bcr/c-abl oncogene protei... 170 8e-42
U19348-1|AAA92686.1| 523|Homo sapiens tpr-met fusion protein pr... 170 1e-41
U08818-1|AAB60323.1| 455|Homo sapiens activated met oncogene pr... 170 1e-41
BC130420-1|AAI30421.1| 1390|Homo sapiens met proto-oncogene (hep... 170 1e-41
AB209898-1|BAD93135.1| 712|Homo sapiens met proto-oncogene prec... 170 1e-41
U18934-1|AAC50070.1| 882|Homo sapiens receptor tyrosine kinase ... 169 1e-41
U05682-1|AAA19236.1| 890|Homo sapiens Rse protein. 169 1e-41
D50479-1|BAA21781.1| 884|Homo sapiens protein-tyrosine kinase p... 169 1e-41
D17517-1|BAA04467.1| 890|Homo sapiens Sky protein. 169 1e-41
BC109099-1|AAI09100.1| 773|Homo sapiens MUSK protein protein. 169 1e-41
BC109098-1|AAI09099.1| 783|Homo sapiens MUSK protein protein. 169 1e-41
BC051756-1|AAH51756.1| 890|Homo sapiens TYRO3 protein tyrosine ... 169 1e-41
BC049368-1|AAH49368.1| 890|Homo sapiens TYRO3 protein tyrosine ... 169 1e-41
BC029925-1|AAH29925.2| 518|Homo sapiens TYRO3 protein protein. 169 1e-41
AL513328-2|CAI17350.1| 867|Homo sapiens muscle, skeletal, recep... 169 1e-41
AL513328-1|CAI17349.1| 875|Homo sapiens muscle, skeletal, recep... 169 1e-41
AL157881-3|CAH69978.1| 867|Homo sapiens muscle, skeletal, recep... 169 1e-41
AL157881-2|CAH69977.1| 875|Homo sapiens muscle, skeletal, recep... 169 1e-41
AL035703-1|CAB81612.1| 1005|Homo sapiens EPH receptor A8 protein. 169 1e-41
AF006464-1|AAB63044.1| 869|Homo sapiens muscle specific tyrosin... 169 1e-41
AB209431-1|BAD92668.1| 951|Homo sapiens TYRO3 protein tyrosine ... 169 1e-41
AB040892-1|BAA95983.1| 853|Homo sapiens KIAA1459 protein protein. 169 1e-41
X72886-1|CAA51396.1| 272|Homo sapiens TYRO3 protein. 169 2e-41
X54559-1|CAB56793.1| 1390|Homo sapiens proto-oncogene protein. 169 2e-41
X02160-1|CAA26096.1| 1370|Homo sapiens protein ( Human mRNA for ... 168 3e-41
M32972-1|AAA59452.1| 1382|Homo sapiens insulin receptor protein. 168 3e-41
M10051-1|AAA59174.1| 1382|Homo sapiens INSR protein. 168 3e-41
BC117172-1|AAI17173.1| 1370|Homo sapiens insulin receptor protein. 168 3e-41
AB208861-1|BAD92098.1| 833|Homo sapiens insulin receptor varian... 168 3e-41
Z29630-1|CAA82737.1| 612|Homo sapiens protein-tyrosine kinase p... 167 6e-41
X73568-1|CAA51970.1| 630|Homo sapiens protein tyrosin kinase pr... 167 6e-41
L28824-1|AAA36526.1| 635|Homo sapiens protein tyrosine kinase p... 167 6e-41
BC011399-1|AAH11399.1| 612|Homo sapiens SYK protein protein. 167 6e-41
BC002962-1|AAH02962.1| 635|Homo sapiens spleen tyrosine kinase ... 167 6e-41
BC001645-1|AAH01645.1| 635|Homo sapiens spleen tyrosine kinase ... 167 6e-41
AL354862-3|CAI16875.1| 612|Homo sapiens spleen tyrosine kinase ... 167 6e-41
AL354862-2|CAI16876.1| 635|Homo sapiens spleen tyrosine kinase ... 167 6e-41
U43522-1|AAC05330.1| 1009|Homo sapiens cell adhesion kinase beta... 167 1e-40
U33284-1|AAC50203.1| 1009|Homo sapiens PYK2 protein. 166 1e-40
S80542-1|AAB35701.1| 1009|Homo sapiens related adhesion focal ty... 166 1e-40
L49207-1|AAB47217.1| 1009|Homo sapiens focal adhesion kinase pro... 166 1e-40
J02958-1|AAA59591.1| 1408|Homo sapiens MET protein. 166 1e-40
BC042599-1|AAH42599.1| 1009|Homo sapiens PTK2B protein tyrosine ... 166 1e-40
BC036651-1|AAH36651.1| 1009|Homo sapiens PTK2B protein tyrosine ... 166 1e-40
AK128371-1|BAC87404.1| 596|Homo sapiens protein ( Homo sapiens ... 166 1e-40
AB209085-1|BAD92322.1| 802|Homo sapiens PTK2B protein tyrosine ... 166 1e-40
S76475-1|AAB33111.1| 839|Homo sapiens trkC protein. 166 2e-40
M25949-1|AAA35593.1| 144|Homo sapiens bcr/c-abl oncogene protei... 166 2e-40
M13099-1|AAA51896.1| 119|Homo sapiens c-abl protein. 166 2e-40
AJ224521-1|CAA12029.1| 839|Homo sapiens TRKC protein. 166 2e-40
J05046-1|AAC31759.1| 1268|Homo sapiens insulin receptor-related ... 165 2e-40
AL158169-3|CAH70009.1| 1297|Homo sapiens insulin receptor-relate... 165 2e-40
U02566-1|AAA17407.1| 723|Homo sapiens receptor tyrosine kinase ... 165 3e-40
X00663-1|CAA25282.1| 800|Homo sapiens protein ( Human mRNA frag... 164 5e-40
X00588-1|CAA25240.1| 1210|Homo sapiens epidermal growth factor r... 164 5e-40
BC094761-1|AAH94761.1| 1091|Homo sapiens EGFR protein protein. 164 5e-40
AY588246-1|AAS83109.1| 1210|Homo sapiens epidermal growth factor... 164 5e-40
AY550966-1|AAT52212.1| 1210|Homo sapiens cell growth inhibiting ... 164 5e-40
AF288738-1|AAG35789.1| 1210|Homo sapiens p170 epidermal growth f... 164 5e-40
AB209442-1|BAD92679.1| 1081|Homo sapiens epidermal growth factor... 164 5e-40
L06139-1|AAA61139.1| 1124|Homo sapiens receptor protein-tyrosine... 163 1e-39
BC035514-1|AAH35514.2| 1124|Homo sapiens TEK tyrosine kinase, en... 163 1e-39
AL133411-1|CAI16055.1| 1124|Homo sapiens TEK tyrosine kinase, en... 163 1e-39
AB208796-1|BAD92033.1| 1157|Homo sapiens TEK tyrosine kinase var... 163 1e-39
AB209338-1|BAD92575.1| 400|Homo sapiens Hypothetical protein FL... 163 2e-39
X60957-1|CAA43290.1| 1138|Homo sapiens receptor tyrosine kinase ... 162 2e-39
BC038239-1|AAH38239.1| 1138|Homo sapiens tyrosine kinase with im... 162 2e-39
AL139289-10|CAI23385.1| 1138|Homo sapiens tyrosine kinase with i... 162 2e-39
AL139289-9|CAI23386.1| 541|Homo sapiens tyrosine kinase with im... 162 2e-39
AF217976-1|AAG17219.1| 421|Homo sapiens unknown protein. 162 2e-39
M14209-1|AAA52441.1| 211|Homo sapiens fes/fps proto-oncogene pr... 162 3e-39
X70040-1|CAA49634.1| 1400|Homo sapiens tyrosine kinase protein. 161 6e-39
X03363-1|CAA27060.1| 1255|Homo sapiens protein ( Human c-erb-B-2... 160 1e-38
M97675-1|AAA60275.1| 937|Homo sapiens transmembrane receptor pr... 160 1e-38
M11730-1|AAA75493.1| 1255|Homo sapiens protein ( Human tyrosine ... 160 1e-38
BC128386-1|AAI28387.1| 940|Homo sapiens ROR1 protein protein. 160 1e-38
AY208911-1|AAO18082.1| 1255|Homo sapiens v-erb-b2 erythroblastic... 160 1e-38
AL445205-2|CAH71706.1| 937|Homo sapiens receptor tyrosine kinas... 160 1e-38
AL161742-2|CAI21932.1| 937|Homo sapiens receptor tyrosine kinas... 160 1e-38
AL137859-2|CAI21732.1| 937|Homo sapiens receptor tyrosine kinas... 160 1e-38
Z29093-1|CAA82335.1| 876|Homo sapiens receptor tyrosine kinase ... 159 3e-38
X98208-1|CAA66871.1| 913|Homo sapiens discoidin receptor tyrosi... 159 3e-38
X74979-1|CAA52915.1| 876|Homo sapiens TrkE protein. 159 3e-38
L57508-1|AAB05208.1| 876|Homo sapiens receptor kinase protein. 159 3e-38
L20817-1|AAA18019.1| 913|Homo sapiens tyrosine protein kinase p... 159 3e-38
BC070070-1|AAH70070.1| 876|Homo sapiens DDR1 protein protein. 159 3e-38
BC013400-1|AAH13400.1| 876|Homo sapiens discoidin domain recept... 159 3e-38
BC008716-1|AAH08716.1| 876|Homo sapiens discoidin domain recept... 159 3e-38
BA000025-66|BAB63318.1| 913|Homo sapiens Receptor tyrosine kina... 159 3e-38
AL773589-2|CAI18534.1| 876|Homo sapiens discoidin domain recept... 159 3e-38
AL773589-1|CAI18533.1| 913|Homo sapiens discoidin domain recept... 159 3e-38
AL773541-2|CAI18450.1| 876|Homo sapiens discoidin domain recept... 159 3e-38
AL773541-1|CAI18451.1| 913|Homo sapiens discoidin domain recept... 159 3e-38
AL662870-7|CAI18442.1| 913|Homo sapiens discoidin domain recept... 159 3e-38
AL662870-6|CAI18441.1| 876|Homo sapiens discoidin domain recept... 159 3e-38
AL662854-7|CAI17433.1| 913|Homo sapiens discoidin domain recept... 159 3e-38
AL662854-6|CAI17434.1| 876|Homo sapiens discoidin domain recept... 159 3e-38
AB210021-1|BAE06103.1| 894|Homo sapiens DDR1 variant protein pr... 159 3e-38
AB202100-1|BAE78621.1| 876|Homo sapiens discoidin domain recept... 159 3e-38
AB103608-1|BAF31270.1| 913|Homo sapiens DDR protein protein. 159 3e-38
AB088102-1|BAC54935.1| 913|Homo sapiens receptor tyrosine kinas... 159 3e-38
X74764-1|CAA52777.1| 855|Homo sapiens protein-tyrosine kinase p... 158 5e-38
BC052998-1|AAH52998.1| 855|Homo sapiens discoidin domain recept... 158 5e-38
AL445197-3|CAI15941.1| 855|Homo sapiens discoidin domain recept... 158 5e-38
U48705-1|AAC50917.1| 913|Homo sapiens tyrosine kinase DDR protein. 157 6e-38
L11315-1|AAA02866.1| 913|Homo sapiens receptor tyrosine kinase ... 157 6e-38
AY513655-1|AAS82867.1| 681|Homo sapiens proto-oncogene c-fes va... 157 6e-38
BC053878-1|AAH53878.1| 619|Homo sapiens zeta-chain (TCR) associ... 157 1e-37
BC039039-1|AAH39039.1| 493|Homo sapiens ZAP70 protein protein. 157 1e-37
AC016699-1|AAX93187.1| 493|Homo sapiens unknown protein. 157 1e-37
AB083211-1|BAC43747.1| 312|Homo sapiens truncated ZAP kinase pr... 157 1e-37
X52213-1|CAA36460.1| 464|Homo sapiens ltk protein. 153 1e-36
AL662870-9|CAM25688.1| 377|Homo sapiens discoidin domain recept... 153 1e-36
AL662854-9|CAM24839.1| 377|Homo sapiens discoidin domain recept... 153 1e-36
X60702-1|CAA43113.1| 803|Homo sapiens tyrosine kinase protein. 153 2e-36
D16105-1|BAA03679.1| 864|Homo sapiens leukocyte tyrosine kinase... 153 2e-36
U66559-1|AAC51104.1| 1620|Homo sapiens anaplastic lymphoma kinas... 151 7e-36
U62540-1|AAB71619.1| 1620|Homo sapiens anaplastic lymphoma kinas... 151 7e-36
U04946-1|AAA58698.1| 680|Homo sapiens nucleophosmin-anaplastic ... 151 7e-36
D45915-1|BAA08343.1| 680|Homo sapiens p80 protein protein. 151 7e-36
AF390893-1|AAM17922.1| 803|Homo sapiens TRK-fused gene/anaplast... 151 7e-36
AF143407-1|AAF27292.1| 756|Homo sapiens TRK-fused gene/anaplast... 151 7e-36
AF125093-1|AAF42734.1| 701|Homo sapiens TRK-fused gene-anaplast... 151 7e-36
AC074096-1|AAY15027.1| 1192|Homo sapiens unknown protein. 151 7e-36
AB209477-1|BAD92714.1| 1626|Homo sapiens anaplastic lymphoma kin... 151 7e-36
M11767-1|AAA35808.1| 295|Homo sapiens protooncogene protein pro... 149 2e-35
L05186-1|AAA35819.1| 879|Homo sapiens focal adhesion kinase pro... 149 2e-35
AF037333-1|AAB94627.1| 943|Homo sapiens Eph-like receptor tyros... 143 1e-33
M34309-1|AAA35979.1| 1342|Homo sapiens protein ( Human epidermal... 141 6e-33
M29366-1|AAA35790.1| 1342|Homo sapiens protein ( Human epidermal... 141 6e-33
BC082992-1|AAH82992.1| 1342|Homo sapiens v-erb-b2 erythroblastic... 141 6e-33
AM051278-1|CAJ19684.1| 197|Homo sapiens dominant-negative kinas... 140 1e-32
U40271-1|AAC50484.2| 1070|Homo sapiens transmembrane receptor pr... 139 2e-32
BC071557-1|AAH71557.1| 1070|Homo sapiens PTK7 protein tyrosine k... 139 2e-32
AM051280-1|CAJ19686.1| 208|Homo sapiens dominant-negative kinas... 139 2e-32
AL355385-4|CAI13783.1| 1070|Homo sapiens PTK7 protein tyrosine k... 139 2e-32
AF531871-1|AAN04865.1| 1014|Homo sapiens transmembrane receptor ... 139 2e-32
AF531870-1|AAN04864.1| 940|Homo sapiens transmembrane receptor ... 139 2e-32
AF531869-1|AAN04863.1| 1030|Homo sapiens transmembrane receptor ... 139 2e-32
AF531868-1|AAN04862.1| 1070|Homo sapiens transmembrane receptor ... 139 2e-32
AF447176-1|AAL39062.1| 1070|Homo sapiens protein tyrosine kinase... 139 2e-32
AL157486-1|CAB75674.1| 364|Homo sapiens hypothetical protein pr... 137 7e-32
BC112933-1|AAI12934.1| 387|Homo sapiens Unknown (protein for MG... 137 9e-32
AJ872185-1|CAI43321.1| 1008|Homo sapiens Ephrin type-A receptor ... 137 9e-32
AF153764-1|AAF37341.1| 172|Homo sapiens Bruton's tyrosine kinas... 136 1e-31
AF153364-1|AAF61477.1| 149|Homo sapiens Bruton's tyrosine kinas... 136 1e-31
AK131215-1|BAD18404.1| 543|Homo sapiens protein ( Homo sapiens ... 135 4e-31
AF153762-1|AAF37339.1| 174|Homo sapiens Bruton's tyrosine kinas... 135 4e-31
AF153761-1|AAF37338.1| 174|Homo sapiens Bruton's tyrosine kinas... 134 6e-31
AF153758-1|AAF37335.1| 174|Homo sapiens Bruton's tyrosine kinas... 134 6e-31
AF153760-1|AAF37337.1| 174|Homo sapiens Bruton's tyrosine kinas... 134 8e-31
AF153759-1|AAF37336.1| 174|Homo sapiens Bruton's tyrosine kinas... 134 8e-31
AF153757-1|AAF37334.1| 174|Homo sapiens Bruton's tyrosine kinas... 134 8e-31
AF153756-1|AAF37333.1| 174|Homo sapiens Bruton's tyrosine kinas... 134 8e-31
AC004416-1|AAF66137.2| 583|Homo sapiens unknown protein. 134 8e-31
AB001872-1|BAA24817.1| 966|Homo sapiens leucine zipper bearing ... 131 4e-30
BC039695-1|AAH39695.1| 1129|Homo sapiens JAK2 protein protein. 130 1e-29
AY973034-1|AAY22962.1| 1132|Homo sapiens Janus kinase 2 protein. 130 1e-29
AL161450-1|CAD13329.1| 1132|Homo sapiens Janus kinase 2 (a prote... 130 1e-29
AF058925-1|AAC23982.1| 1132|Homo sapiens Jak2 kinase protein. 130 1e-29
AF005216-1|AAB82092.1| 1132|Homo sapiens receptor-associated tyr... 130 1e-29
AF001362-1|AAC23653.1| 1132|Homo sapiens Jak2 kinase protein. 130 1e-29
U33635-1|AAA87565.1| 1070|Homo sapiens colon carcinoma kinase-4 ... 130 1e-29
BC133706-1|AAI33707.1| 1104|Homo sapiens MAP3K9 protein protein. 129 2e-29
BC111407-1|AAI11408.1| 1103|Homo sapiens MAP3K9 protein protein. 129 2e-29
AY327900-1|AAQ23054.1| 1104|Homo sapiens mixed-lineage protein k... 129 2e-29
AF251442-1|AAG44591.1| 1066|Homo sapiens mixed lineage kinase ML... 129 2e-29
U07358-1|AAA67343.1| 859|Homo sapiens serine/threonine protein ... 128 4e-29
BC050050-1|AAH50050.1| 567|Homo sapiens MAP3K12 protein protein. 128 4e-29
AF283475-1|AAL67158.1| 859|Homo sapiens zipper protein kinase p... 128 4e-29
Z26652-1|CAA81393.1| 993|Homo sapiens FLT3 receptor tyrosine ki... 127 1e-28
U02687-1|AAA18947.1| 993|Homo sapiens serine/threonine protein ... 127 1e-28
L36162-1|AAA35487.1| 160|Homo sapiens receptor tyrosine kinase ... 127 1e-28
BC126350-1|AAI26351.1| 993|Homo sapiens fms-related tyrosine ki... 127 1e-28
M64174-1|AAA36527.1| 1142|Homo sapiens protein-tyrosine kinase p... 126 1e-28
BC132729-1|AAI32730.1| 1154|Homo sapiens Janus kinase 1 (a prote... 126 2e-28
AB209057-1|BAD92294.1| 1154|Homo sapiens janus kinase 1 variant ... 126 2e-28
U43408-1|AAC50427.1| 666|Homo sapiens tyrosine kinase protein. 126 2e-28
Z48615-1|CAA88531.1| 953|Homo sapiens serine/threonine kinase w... 125 4e-28
X90846-1|CAA62351.1| 954|Homo sapiens mixed lineage kinase 2 pr... 125 4e-28
BC035782-1|AAH35782.1| 661|Homo sapiens TNK1 protein protein. 125 4e-28
AF097738-1|AAC99412.1| 661|Homo sapiens non-receptor tyosine ki... 125 4e-28
AB209118-1|BAD92355.1| 781|Homo sapiens BDNF/NT-3 growth factor... 125 4e-28
>X16416-1|CAA34438.1| 1130|Homo sapiens protein ( Human c-abl mRNA
encoding p150 protein. ).
Length = 1130
Score = 686 bits (1696), Expect = 0.0
Identities = 315/412 (76%), Positives = 361/412 (87%), Gaps = 3/412 (0%)
Query: 53 ANRWTSKENLLAHHEEDDPQLFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHT 112
A RW SKENLLA E+DP LFVALYDF A G+N L++ KGE++R++ YN +GEWCEA T
Sbjct: 45 AARWNSKENLLAGPSENDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQT 104
Query: 113 LTGAVGWVPSNYVTPVNSLEKHSWYHGPISRNAAEYLLSSGINGSFLVRESESSPGQRSI 172
G GWVPSNY+TPVNSLEKHSWYHGP+SRNAAEYLLSSGINGSFLVRESESSPGQRSI
Sbjct: 105 KNGQ-GWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSI 163
Query: 173 SLRYEGRVYHYRINEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKP 232
SLRYEGRVYHYRIN +DGK+YV+SES+F TLAELVHHHS DGLIT L YPAPKR+KP
Sbjct: 164 SLRYEGRVYHYRINTASDGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRNKP 223
Query: 233 TVFPLAPP-DHWEIDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDF 291
TV+ ++P D WE++RTDI MKHKLGGGQYG+VYE WK+ ++TVAVKTLK+DTM +++F
Sbjct: 224 TVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEF 283
Query: 292 LEEASIMKEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMY 351
L+EA++MKE++HPNLVQLLGVCTREPPFYIITEFM+ GNLL+YLR R+ V AVVL+Y
Sbjct: 284 LKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEV-NAVVLLY 342
Query: 352 MATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFP 411
MATQI+S M YLE ++FIHRDLAARNCLVGENHLVKVADFGL+RLM DTYTAHAGAKFP
Sbjct: 343 MATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFP 402
Query: 412 IKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
IKWTAPE LAYN FS KSDVWAFG+LLWEIATYGMSPYPG+DL+ VY +LEK
Sbjct: 403 IKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEK 454
>U07563-2|AAB60394.1| 1130|Homo sapiens proto-oncogene
tyrosine-protein kinase protein.
Length = 1130
Score = 686 bits (1696), Expect = 0.0
Identities = 315/412 (76%), Positives = 361/412 (87%), Gaps = 3/412 (0%)
Query: 53 ANRWTSKENLLAHHEEDDPQLFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHT 112
A RW SKENLLA E+DP LFVALYDF A G+N L++ KGE++R++ YN +GEWCEA T
Sbjct: 45 AARWNSKENLLAGPSENDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQT 104
Query: 113 LTGAVGWVPSNYVTPVNSLEKHSWYHGPISRNAAEYLLSSGINGSFLVRESESSPGQRSI 172
G GWVPSNY+TPVNSLEKHSWYHGP+SRNAAEYLLSSGINGSFLVRESESSPGQRSI
Sbjct: 105 KNGQ-GWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSI 163
Query: 173 SLRYEGRVYHYRINEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKP 232
SLRYEGRVYHYRIN +DGK+YV+SES+F TLAELVHHHS DGLIT L YPAPKR+KP
Sbjct: 164 SLRYEGRVYHYRINTASDGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRNKP 223
Query: 233 TVFPLAPP-DHWEIDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDF 291
TV+ ++P D WE++RTDI MKHKLGGGQYG+VYE WK+ ++TVAVKTLK+DTM +++F
Sbjct: 224 TVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEF 283
Query: 292 LEEASIMKEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMY 351
L+EA++MKE++HPNLVQLLGVCTREPPFYIITEFM+ GNLL+YLR R+ V AVVL+Y
Sbjct: 284 LKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEV-NAVVLLY 342
Query: 352 MATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFP 411
MATQI+S M YLE ++FIHRDLAARNCLVGENHLVKVADFGL+RLM DTYTAHAGAKFP
Sbjct: 343 MATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFP 402
Query: 412 IKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
IKWTAPE LAYN FS KSDVWAFG+LLWEIATYGMSPYPG+DL+ VY +LEK
Sbjct: 403 IKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEK 454
>U07563-1|AAB60393.1| 1149|Homo sapiens proto-oncogene
tyrosine-protein kinase protein.
Length = 1149
Score = 686 bits (1696), Expect = 0.0
Identities = 315/412 (76%), Positives = 361/412 (87%), Gaps = 3/412 (0%)
Query: 53 ANRWTSKENLLAHHEEDDPQLFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHT 112
A RW SKENLLA E+DP LFVALYDF A G+N L++ KGE++R++ YN +GEWCEA T
Sbjct: 64 AARWNSKENLLAGPSENDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQT 123
Query: 113 LTGAVGWVPSNYVTPVNSLEKHSWYHGPISRNAAEYLLSSGINGSFLVRESESSPGQRSI 172
G GWVPSNY+TPVNSLEKHSWYHGP+SRNAAEYLLSSGINGSFLVRESESSPGQRSI
Sbjct: 124 KNGQ-GWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSI 182
Query: 173 SLRYEGRVYHYRINEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKP 232
SLRYEGRVYHYRIN +DGK+YV+SES+F TLAELVHHHS DGLIT L YPAPKR+KP
Sbjct: 183 SLRYEGRVYHYRINTASDGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRNKP 242
Query: 233 TVFPLAPP-DHWEIDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDF 291
TV+ ++P D WE++RTDI MKHKLGGGQYG+VYE WK+ ++TVAVKTLK+DTM +++F
Sbjct: 243 TVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEF 302
Query: 292 LEEASIMKEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMY 351
L+EA++MKE++HPNLVQLLGVCTREPPFYIITEFM+ GNLL+YLR R+ V AVVL+Y
Sbjct: 303 LKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEV-NAVVLLY 361
Query: 352 MATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFP 411
MATQI+S M YLE ++FIHRDLAARNCLVGENHLVKVADFGL+RLM DTYTAHAGAKFP
Sbjct: 362 MATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFP 421
Query: 412 IKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
IKWTAPE LAYN FS KSDVWAFG+LLWEIATYGMSPYPG+DL+ VY +LEK
Sbjct: 422 IKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEK 473
>DQ145721-1|AAZ38718.1| 1149|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 protein.
Length = 1149
Score = 686 bits (1696), Expect = 0.0
Identities = 315/412 (76%), Positives = 361/412 (87%), Gaps = 3/412 (0%)
Query: 53 ANRWTSKENLLAHHEEDDPQLFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHT 112
A RW SKENLLA E+DP LFVALYDF A G+N L++ KGE++R++ YN +GEWCEA T
Sbjct: 64 AARWNSKENLLAGPSENDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQT 123
Query: 113 LTGAVGWVPSNYVTPVNSLEKHSWYHGPISRNAAEYLLSSGINGSFLVRESESSPGQRSI 172
G GWVPSNY+TPVNSLEKHSWYHGP+SRNAAEYLLSSGINGSFLVRESESSPGQRSI
Sbjct: 124 KNGQ-GWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSI 182
Query: 173 SLRYEGRVYHYRINEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKP 232
SLRYEGRVYHYRIN +DGK+YV+SES+F TLAELVHHHS DGLIT L YPAPKR+KP
Sbjct: 183 SLRYEGRVYHYRINTASDGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRNKP 242
Query: 233 TVFPLAPP-DHWEIDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDF 291
TV+ ++P D WE++RTDI MKHKLGGGQYG+VYE WK+ ++TVAVKTLK+DTM +++F
Sbjct: 243 TVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEF 302
Query: 292 LEEASIMKEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMY 351
L+EA++MKE++HPNLVQLLGVCTREPPFYIITEFM+ GNLL+YLR R+ V AVVL+Y
Sbjct: 303 LKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEV-NAVVLLY 361
Query: 352 MATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFP 411
MATQI+S M YLE ++FIHRDLAARNCLVGENHLVKVADFGL+RLM DTYTAHAGAKFP
Sbjct: 362 MATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFP 421
Query: 412 IKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
IKWTAPE LAYN FS KSDVWAFG+LLWEIATYGMSPYPG+DL+ VY +LEK
Sbjct: 422 IKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEK 473
>BC117451-1|AAI17452.1| 1149|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 protein.
Length = 1149
Score = 686 bits (1696), Expect = 0.0
Identities = 315/412 (76%), Positives = 361/412 (87%), Gaps = 3/412 (0%)
Query: 53 ANRWTSKENLLAHHEEDDPQLFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHT 112
A RW SKENLLA E+DP LFVALYDF A G+N L++ KGE++R++ YN +GEWCEA T
Sbjct: 64 AARWNSKENLLAGPSENDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQT 123
Query: 113 LTGAVGWVPSNYVTPVNSLEKHSWYHGPISRNAAEYLLSSGINGSFLVRESESSPGQRSI 172
G GWVPSNY+TPVNSLEKHSWYHGP+SRNAAEYLLSSGINGSFLVRESESSPGQRSI
Sbjct: 124 KNGQ-GWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSI 182
Query: 173 SLRYEGRVYHYRINEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKP 232
SLRYEGRVYHYRIN +DGK+YV+SES+F TLAELVHHHS DGLIT L YPAPKR+KP
Sbjct: 183 SLRYEGRVYHYRINTASDGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRNKP 242
Query: 233 TVFPLAPP-DHWEIDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDF 291
TV+ ++P D WE++RTDI MKHKLGGGQYG+VYE WK+ ++TVAVKTLK+DTM +++F
Sbjct: 243 TVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEF 302
Query: 292 LEEASIMKEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMY 351
L+EA++MKE++HPNLVQLLGVCTREPPFYIITEFM+ GNLL+YLR R+ V AVVL+Y
Sbjct: 303 LKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEV-NAVVLLY 361
Query: 352 MATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFP 411
MATQI+S M YLE ++FIHRDLAARNCLVGENHLVKVADFGL+RLM DTYTAHAGAKFP
Sbjct: 362 MATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFP 421
Query: 412 IKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
IKWTAPE LAYN FS KSDVWAFG+LLWEIATYGMSPYPG+DL+ VY +LEK
Sbjct: 422 IKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEK 473
>AL359092-11|CAM45752.1| 1149|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 protein.
Length = 1149
Score = 686 bits (1696), Expect = 0.0
Identities = 315/412 (76%), Positives = 361/412 (87%), Gaps = 3/412 (0%)
Query: 53 ANRWTSKENLLAHHEEDDPQLFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHT 112
A RW SKENLLA E+DP LFVALYDF A G+N L++ KGE++R++ YN +GEWCEA T
Sbjct: 64 AARWNSKENLLAGPSENDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQT 123
Query: 113 LTGAVGWVPSNYVTPVNSLEKHSWYHGPISRNAAEYLLSSGINGSFLVRESESSPGQRSI 172
G GWVPSNY+TPVNSLEKHSWYHGP+SRNAAEYLLSSGINGSFLVRESESSPGQRSI
Sbjct: 124 KNGQ-GWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSI 182
Query: 173 SLRYEGRVYHYRINEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKP 232
SLRYEGRVYHYRIN +DGK+YV+SES+F TLAELVHHHS DGLIT L YPAPKR+KP
Sbjct: 183 SLRYEGRVYHYRINTASDGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRNKP 242
Query: 233 TVFPLAPP-DHWEIDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDF 291
TV+ ++P D WE++RTDI MKHKLGGGQYG+VYE WK+ ++TVAVKTLK+DTM +++F
Sbjct: 243 TVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEF 302
Query: 292 LEEASIMKEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMY 351
L+EA++MKE++HPNLVQLLGVCTREPPFYIITEFM+ GNLL+YLR R+ V AVVL+Y
Sbjct: 303 LKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEV-NAVVLLY 361
Query: 352 MATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFP 411
MATQI+S M YLE ++FIHRDLAARNCLVGENHLVKVADFGL+RLM DTYTAHAGAKFP
Sbjct: 362 MATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFP 421
Query: 412 IKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
IKWTAPE LAYN FS KSDVWAFG+LLWEIATYGMSPYPG+DL+ VY +LEK
Sbjct: 422 IKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEK 473
>AL161733-3|CAM45756.1| 1149|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 protein.
Length = 1149
Score = 686 bits (1696), Expect = 0.0
Identities = 315/412 (76%), Positives = 361/412 (87%), Gaps = 3/412 (0%)
Query: 53 ANRWTSKENLLAHHEEDDPQLFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHT 112
A RW SKENLLA E+DP LFVALYDF A G+N L++ KGE++R++ YN +GEWCEA T
Sbjct: 64 AARWNSKENLLAGPSENDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQT 123
Query: 113 LTGAVGWVPSNYVTPVNSLEKHSWYHGPISRNAAEYLLSSGINGSFLVRESESSPGQRSI 172
G GWVPSNY+TPVNSLEKHSWYHGP+SRNAAEYLLSSGINGSFLVRESESSPGQRSI
Sbjct: 124 KNGQ-GWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSI 182
Query: 173 SLRYEGRVYHYRINEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKP 232
SLRYEGRVYHYRIN +DGK+YV+SES+F TLAELVHHHS DGLIT L YPAPKR+KP
Sbjct: 183 SLRYEGRVYHYRINTASDGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRNKP 242
Query: 233 TVFPLAPP-DHWEIDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDF 291
TV+ ++P D WE++RTDI MKHKLGGGQYG+VYE WK+ ++TVAVKTLK+DTM +++F
Sbjct: 243 TVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEF 302
Query: 292 LEEASIMKEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMY 351
L+EA++MKE++HPNLVQLLGVCTREPPFYIITEFM+ GNLL+YLR R+ V AVVL+Y
Sbjct: 303 LKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEV-NAVVLLY 361
Query: 352 MATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFP 411
MATQI+S M YLE ++FIHRDLAARNCLVGENHLVKVADFGL+RLM DTYTAHAGAKFP
Sbjct: 362 MATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFP 421
Query: 412 IKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
IKWTAPE LAYN FS KSDVWAFG+LLWEIATYGMSPYPG+DL+ VY +LEK
Sbjct: 422 IKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEK 473
>AL161733-1|CAM45754.1| 1130|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 protein.
Length = 1130
Score = 686 bits (1696), Expect = 0.0
Identities = 315/412 (76%), Positives = 361/412 (87%), Gaps = 3/412 (0%)
Query: 53 ANRWTSKENLLAHHEEDDPQLFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHT 112
A RW SKENLLA E+DP LFVALYDF A G+N L++ KGE++R++ YN +GEWCEA T
Sbjct: 45 AARWNSKENLLAGPSENDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQT 104
Query: 113 LTGAVGWVPSNYVTPVNSLEKHSWYHGPISRNAAEYLLSSGINGSFLVRESESSPGQRSI 172
G GWVPSNY+TPVNSLEKHSWYHGP+SRNAAEYLLSSGINGSFLVRESESSPGQRSI
Sbjct: 105 KNGQ-GWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSI 163
Query: 173 SLRYEGRVYHYRINEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKP 232
SLRYEGRVYHYRIN +DGK+YV+SES+F TLAELVHHHS DGLIT L YPAPKR+KP
Sbjct: 164 SLRYEGRVYHYRINTASDGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRNKP 223
Query: 233 TVFPLAPP-DHWEIDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDF 291
TV+ ++P D WE++RTDI MKHKLGGGQYG+VYE WK+ ++TVAVKTLK+DTM +++F
Sbjct: 224 TVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEF 283
Query: 292 LEEASIMKEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMY 351
L+EA++MKE++HPNLVQLLGVCTREPPFYIITEFM+ GNLL+YLR R+ V AVVL+Y
Sbjct: 284 LKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEV-NAVVLLY 342
Query: 352 MATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFP 411
MATQI+S M YLE ++FIHRDLAARNCLVGENHLVKVADFGL+RLM DTYTAHAGAKFP
Sbjct: 343 MATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFP 402
Query: 412 IKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
IKWTAPE LAYN FS KSDVWAFG+LLWEIATYGMSPYPG+DL+ VY +LEK
Sbjct: 403 IKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEK 454
>AB209456-1|BAD92693.1| 1167|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 isoform b variant
protein.
Length = 1167
Score = 686 bits (1696), Expect = 0.0
Identities = 315/412 (76%), Positives = 361/412 (87%), Gaps = 3/412 (0%)
Query: 53 ANRWTSKENLLAHHEEDDPQLFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHT 112
A RW SKENLLA E+DP LFVALYDF A G+N L++ KGE++R++ YN +GEWCEA T
Sbjct: 82 AARWNSKENLLAGPSENDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQT 141
Query: 113 LTGAVGWVPSNYVTPVNSLEKHSWYHGPISRNAAEYLLSSGINGSFLVRESESSPGQRSI 172
G GWVPSNY+TPVNSLEKHSWYHGP+SRNAAEYLLSSGINGSFLVRESESSPGQRSI
Sbjct: 142 KNGQ-GWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSI 200
Query: 173 SLRYEGRVYHYRINEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKP 232
SLRYEGRVYHYRIN +DGK+YV+SES+F TLAELVHHHS DGLIT L YPAPKR+KP
Sbjct: 201 SLRYEGRVYHYRINTASDGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRNKP 260
Query: 233 TVFPLAPP-DHWEIDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDF 291
TV+ ++P D WE++RTDI MKHKLGGGQYG+VYE WK+ ++TVAVKTLK+DTM +++F
Sbjct: 261 TVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEF 320
Query: 292 LEEASIMKEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMY 351
L+EA++MKE++HPNLVQLLGVCTREPPFYIITEFM+ GNLL+YLR R+ V AVVL+Y
Sbjct: 321 LKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEV-NAVVLLY 379
Query: 352 MATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFP 411
MATQI+S M YLE ++FIHRDLAARNCLVGENHLVKVADFGL+RLM DTYTAHAGAKFP
Sbjct: 380 MATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFP 439
Query: 412 IKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
IKWTAPE LAYN FS KSDVWAFG+LLWEIATYGMSPYPG+DL+ VY +LEK
Sbjct: 440 IKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEK 491
>M14752-1|AAA51561.1| 1130|Homo sapiens ABL1 protein.
Length = 1130
Score = 679 bits (1677), Expect = 0.0
Identities = 312/412 (75%), Positives = 358/412 (86%), Gaps = 3/412 (0%)
Query: 53 ANRWTSKENLLAHHEEDDPQLFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHT 112
A RW SKENLLA E+DP LFVALYDF A G+N L++ KGE++R++ YN +GEWCEA T
Sbjct: 45 AARWNSKENLLAGPSENDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQT 104
Query: 113 LTGAVGWVPSNYVTPVNSLEKHSWYHGPISRNAAEYLLSSGINGSFLVRESESSPGQRSI 172
G GWVPSNY+TPVNSLEKHSWYHGP+SRNAAEY LSSGINGSFLVRESESSP QRSI
Sbjct: 105 KNGQ-GWVPSNYITPVNSLEKHSWYHGPVSRNAAEYPLSSGINGSFLVRESESSPSQRSI 163
Query: 173 SLRYEGRVYHYRINEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKP 232
SLRYEGRVYHYRIN +DGK+YV+SES+F TLAELVHHHS DGLIT L YPAPKR+KP
Sbjct: 164 SLRYEGRVYHYRINTASDGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRNKP 223
Query: 233 TVFPLAPP-DHWEIDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDF 291
TV+ ++P D WE++RTDI MKHKLGGGQYG+VYE WK+ ++TVAVKTLK+DTM +++F
Sbjct: 224 TVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEF 283
Query: 292 LEEASIMKEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMY 351
L+EA++MKE++HPNLVQLLGVCTREPPFYIITEFM+ GNLL+YLR R+ V AVVL+Y
Sbjct: 284 LKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEV-NAVVLLY 342
Query: 352 MATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFP 411
MATQI+S M YLE ++FIHRDLAARNCLVGENHLVKVADFGL+RLM DTYTAHAGAKFP
Sbjct: 343 MATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFP 402
Query: 412 IKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
IKWTAPE LAYN FS KSDVWAFG+LLWEIATYGMSPYPG+D + VY +LEK
Sbjct: 403 IKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDRSQVYELLEK 454
>M35296-1|AAA35553.1| 1182|Homo sapiens protein ( Human tyrosine
kinase arg gene mRNA. ).
Length = 1182
Score = 658 bits (1626), Expect = 0.0
Identities = 305/412 (74%), Positives = 354/412 (85%), Gaps = 4/412 (0%)
Query: 53 ANRWTSKENLLAHHEEDDPQLFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHT 112
A RW+SKENLL E DP LFVALYDF A G+N L++ KGE++R++ YN++GEW E +
Sbjct: 92 AIRWSSKENLLGA-TESDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNQNGEWSEVRS 150
Query: 113 LTGAVGWVPSNYVTPVNSLEKHSWYHGPISRNAAEYLLSSGINGSFLVRESESSPGQRSI 172
G GWVPSNY+TPVNSLEKHSWYHGP+SR+AAEYLLSS INGSFLVRESESSPGQ SI
Sbjct: 151 KNGQ-GWVPSNYITPVNSLEKHSWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSI 209
Query: 173 SLRYEGRVYHYRINEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKP 232
SLRYEGRVYHYRIN ADGKVYVT+ES+F TLAELVHHHS DGL+T L YPAPK +KP
Sbjct: 210 SLRYEGRVYHYRINTTADGKVYVTAESRFSTLAELVHHHSTVADGLVTTLHYPAPKCNKP 269
Query: 233 TVFPLAP-PDHWEIDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDF 291
TV+ ++P D WE++RTDI MKHKLGGGQYG+VY WK+ ++TVAVKTLK+DTM +++F
Sbjct: 270 TVYGVSPIHDKWEMERTDITMKHKLGGGQYGEVYVGVWKKYSLTVAVKTLKEDTMEVEEF 329
Query: 292 LEEASIMKEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMY 351
L+EA++MKE++HPNLVQLLGVCT EPPFYI+TE+M GNLL+YLR RE V AVVL+Y
Sbjct: 330 LKEAAVMKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLRECNREEVT-AVVLLY 388
Query: 352 MATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFP 411
MATQI+S M YLE ++FIHRDLAARNCLVGENH+VKVADFGL+RLM DTYTAHAGAKFP
Sbjct: 389 MATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLMTGDTYTAHAGAKFP 448
Query: 412 IKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
IKWTAPE LAYNTFS KSDVWAFG+LLWEIATYGMSPYPG+DL+ VY +LEK
Sbjct: 449 IKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEK 500
>DQ009672-1|AAY16984.1| 1182|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1182
Score = 658 bits (1626), Expect = 0.0
Identities = 305/412 (74%), Positives = 354/412 (85%), Gaps = 4/412 (0%)
Query: 53 ANRWTSKENLLAHHEEDDPQLFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHT 112
A RW+SKENLL E DP LFVALYDF A G+N L++ KGE++R++ YN++GEW E +
Sbjct: 92 AIRWSSKENLLGA-TESDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNQNGEWSEVRS 150
Query: 113 LTGAVGWVPSNYVTPVNSLEKHSWYHGPISRNAAEYLLSSGINGSFLVRESESSPGQRSI 172
G GWVPSNY+TPVNSLEKHSWYHGP+SR+AAEYLLSS INGSFLVRESESSPGQ SI
Sbjct: 151 KNGQ-GWVPSNYITPVNSLEKHSWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSI 209
Query: 173 SLRYEGRVYHYRINEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKP 232
SLRYEGRVYHYRIN ADGKVYVT+ES+F TLAELVHHHS DGL+T L YPAPK +KP
Sbjct: 210 SLRYEGRVYHYRINTTADGKVYVTAESRFSTLAELVHHHSTVADGLVTTLHYPAPKCNKP 269
Query: 233 TVFPLAP-PDHWEIDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDF 291
TV+ ++P D WE++RTDI MKHKLGGGQYG+VY WK+ ++TVAVKTLK+DTM +++F
Sbjct: 270 TVYGVSPIHDKWEMERTDITMKHKLGGGQYGEVYVGVWKKYSLTVAVKTLKEDTMEVEEF 329
Query: 292 LEEASIMKEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMY 351
L+EA++MKE++HPNLVQLLGVCT EPPFYI+TE+M GNLL+YLR RE V AVVL+Y
Sbjct: 330 LKEAAVMKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLRECNREEVT-AVVLLY 388
Query: 352 MATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFP 411
MATQI+S M YLE ++FIHRDLAARNCLVGENH+VKVADFGL+RLM DTYTAHAGAKFP
Sbjct: 389 MATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLMTGDTYTAHAGAKFP 448
Query: 412 IKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
IKWTAPE LAYNTFS KSDVWAFG+LLWEIATYGMSPYPG+DL+ VY +LEK
Sbjct: 449 IKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEK 500
>BX538317-1|CAD98092.1| 1092|Homo sapiens hypothetical protein
protein.
Length = 1092
Score = 658 bits (1626), Expect = 0.0
Identities = 305/412 (74%), Positives = 354/412 (85%), Gaps = 4/412 (0%)
Query: 53 ANRWTSKENLLAHHEEDDPQLFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHT 112
A RW+SKENLL E DP LFVALYDF A G+N L++ KGE++R++ YN++GEW E +
Sbjct: 105 AIRWSSKENLLGA-TESDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNQNGEWSEVRS 163
Query: 113 LTGAVGWVPSNYVTPVNSLEKHSWYHGPISRNAAEYLLSSGINGSFLVRESESSPGQRSI 172
G GWVPSNY+TPVNSLEKHSWYHGP+SR+AAEYLLSS INGSFLVRESESSPGQ SI
Sbjct: 164 KNGQ-GWVPSNYITPVNSLEKHSWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSI 222
Query: 173 SLRYEGRVYHYRINEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKP 232
SLRYEGRVYHYRIN ADGKVYVT+ES+F TLAELVHHHS DGL+T L YPAPK +KP
Sbjct: 223 SLRYEGRVYHYRINTTADGKVYVTAESRFSTLAELVHHHSTVADGLVTTLHYPAPKCNKP 282
Query: 233 TVFPLAP-PDHWEIDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDF 291
TV+ ++P D WE++RTDI MKHKLGGGQYG+VY WK+ ++TVAVKTLK+DTM +++F
Sbjct: 283 TVYGVSPIHDKWEMERTDITMKHKLGGGQYGEVYVGVWKKYSLTVAVKTLKEDTMEVEEF 342
Query: 292 LEEASIMKEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMY 351
L+EA++MKE++HPNLVQLLGVCT EPPFYI+TE+M GNLL+YLR RE V AVVL+Y
Sbjct: 343 LKEAAVMKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLRECNREEVT-AVVLLY 401
Query: 352 MATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFP 411
MATQI+S M YLE ++FIHRDLAARNCLVGENH+VKVADFGL+RLM DTYTAHAGAKFP
Sbjct: 402 MATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLMTGDTYTAHAGAKFP 461
Query: 412 IKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
IKWTAPE LAYNTFS KSDVWAFG+LLWEIATYGMSPYPG+DL+ VY +LEK
Sbjct: 462 IKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEK 513
>BC065912-1|AAH65912.1| 1167|Homo sapiens ABL2 protein protein.
Length = 1167
Score = 658 bits (1626), Expect = 0.0
Identities = 305/412 (74%), Positives = 354/412 (85%), Gaps = 4/412 (0%)
Query: 53 ANRWTSKENLLAHHEEDDPQLFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHT 112
A RW+SKENLL E DP LFVALYDF A G+N L++ KGE++R++ YN++GEW E +
Sbjct: 77 AIRWSSKENLLGA-TESDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNQNGEWSEVRS 135
Query: 113 LTGAVGWVPSNYVTPVNSLEKHSWYHGPISRNAAEYLLSSGINGSFLVRESESSPGQRSI 172
G GWVPSNY+TPVNSLEKHSWYHGP+SR+AAEYLLSS INGSFLVRESESSPGQ SI
Sbjct: 136 KNGQ-GWVPSNYITPVNSLEKHSWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSI 194
Query: 173 SLRYEGRVYHYRINEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKP 232
SLRYEGRVYHYRIN ADGKVYVT+ES+F TLAELVHHHS DGL+T L YPAPK +KP
Sbjct: 195 SLRYEGRVYHYRINTTADGKVYVTAESRFSTLAELVHHHSTVADGLVTTLHYPAPKCNKP 254
Query: 233 TVFPLAP-PDHWEIDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDF 291
TV+ ++P D WE++RTDI MKHKLGGGQYG+VY WK+ ++TVAVKTLK+DTM +++F
Sbjct: 255 TVYGVSPIHDKWEMERTDITMKHKLGGGQYGEVYVGVWKKYSLTVAVKTLKEDTMEVEEF 314
Query: 292 LEEASIMKEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMY 351
L+EA++MKE++HPNLVQLLGVCT EPPFYI+TE+M GNLL+YLR RE V AVVL+Y
Sbjct: 315 LKEAAVMKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLRECNREEVT-AVVLLY 373
Query: 352 MATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFP 411
MATQI+S M YLE ++FIHRDLAARNCLVGENH+VKVADFGL+RLM DTYTAHAGAKFP
Sbjct: 374 MATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLMTGDTYTAHAGAKFP 433
Query: 412 IKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
IKWTAPE LAYNTFS KSDVWAFG+LLWEIATYGMSPYPG+DL+ VY +LEK
Sbjct: 434 IKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEK 485
>AL512326-6|CAI13570.1| 1182|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1182
Score = 658 bits (1626), Expect = 0.0
Identities = 305/412 (74%), Positives = 354/412 (85%), Gaps = 4/412 (0%)
Query: 53 ANRWTSKENLLAHHEEDDPQLFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHT 112
A RW+SKENLL E DP LFVALYDF A G+N L++ KGE++R++ YN++GEW E +
Sbjct: 92 AIRWSSKENLLGA-TESDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNQNGEWSEVRS 150
Query: 113 LTGAVGWVPSNYVTPVNSLEKHSWYHGPISRNAAEYLLSSGINGSFLVRESESSPGQRSI 172
G GWVPSNY+TPVNSLEKHSWYHGP+SR+AAEYLLSS INGSFLVRESESSPGQ SI
Sbjct: 151 KNGQ-GWVPSNYITPVNSLEKHSWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSI 209
Query: 173 SLRYEGRVYHYRINEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKP 232
SLRYEGRVYHYRIN ADGKVYVT+ES+F TLAELVHHHS DGL+T L YPAPK +KP
Sbjct: 210 SLRYEGRVYHYRINTTADGKVYVTAESRFSTLAELVHHHSTVADGLVTTLHYPAPKCNKP 269
Query: 233 TVFPLAP-PDHWEIDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDF 291
TV+ ++P D WE++RTDI MKHKLGGGQYG+VY WK+ ++TVAVKTLK+DTM +++F
Sbjct: 270 TVYGVSPIHDKWEMERTDITMKHKLGGGQYGEVYVGVWKKYSLTVAVKTLKEDTMEVEEF 329
Query: 292 LEEASIMKEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMY 351
L+EA++MKE++HPNLVQLLGVCT EPPFYI+TE+M GNLL+YLR RE V AVVL+Y
Sbjct: 330 LKEAAVMKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLRECNREEVT-AVVLLY 388
Query: 352 MATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFP 411
MATQI+S M YLE ++FIHRDLAARNCLVGENH+VKVADFGL+RLM DTYTAHAGAKFP
Sbjct: 389 MATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLMTGDTYTAHAGAKFP 448
Query: 412 IKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
IKWTAPE LAYNTFS KSDVWAFG+LLWEIATYGMSPYPG+DL+ VY +LEK
Sbjct: 449 IKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEK 500
>AL512326-2|CAI13566.1| 1064|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1064
Score = 658 bits (1626), Expect = 0.0
Identities = 305/412 (74%), Positives = 354/412 (85%), Gaps = 4/412 (0%)
Query: 53 ANRWTSKENLLAHHEEDDPQLFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHT 112
A RW+SKENLL E DP LFVALYDF A G+N L++ KGE++R++ YN++GEW E +
Sbjct: 77 AIRWSSKENLLGA-TESDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNQNGEWSEVRS 135
Query: 113 LTGAVGWVPSNYVTPVNSLEKHSWYHGPISRNAAEYLLSSGINGSFLVRESESSPGQRSI 172
G GWVPSNY+TPVNSLEKHSWYHGP+SR+AAEYLLSS INGSFLVRESESSPGQ SI
Sbjct: 136 KNGQ-GWVPSNYITPVNSLEKHSWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSI 194
Query: 173 SLRYEGRVYHYRINEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKP 232
SLRYEGRVYHYRIN ADGKVYVT+ES+F TLAELVHHHS DGL+T L YPAPK +KP
Sbjct: 195 SLRYEGRVYHYRINTTADGKVYVTAESRFSTLAELVHHHSTVADGLVTTLHYPAPKCNKP 254
Query: 233 TVFPLAP-PDHWEIDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDF 291
TV+ ++P D WE++RTDI MKHKLGGGQYG+VY WK+ ++TVAVKTLK+DTM +++F
Sbjct: 255 TVYGVSPIHDKWEMERTDITMKHKLGGGQYGEVYVGVWKKYSLTVAVKTLKEDTMEVEEF 314
Query: 292 LEEASIMKEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMY 351
L+EA++MKE++HPNLVQLLGVCT EPPFYI+TE+M GNLL+YLR RE V AVVL+Y
Sbjct: 315 LKEAAVMKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLRECNREEVT-AVVLLY 373
Query: 352 MATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFP 411
MATQI+S M YLE ++FIHRDLAARNCLVGENH+VKVADFGL+RLM DTYTAHAGAKFP
Sbjct: 374 MATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLMTGDTYTAHAGAKFP 433
Query: 412 IKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
IKWTAPE LAYNTFS KSDVWAFG+LLWEIATYGMSPYPG+DL+ VY +LEK
Sbjct: 434 IKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEK 485
>AL359179-2|CAI15585.1| 1182|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1182
Score = 658 bits (1626), Expect = 0.0
Identities = 305/412 (74%), Positives = 354/412 (85%), Gaps = 4/412 (0%)
Query: 53 ANRWTSKENLLAHHEEDDPQLFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHT 112
A RW+SKENLL E DP LFVALYDF A G+N L++ KGE++R++ YN++GEW E +
Sbjct: 92 AIRWSSKENLLGA-TESDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNQNGEWSEVRS 150
Query: 113 LTGAVGWVPSNYVTPVNSLEKHSWYHGPISRNAAEYLLSSGINGSFLVRESESSPGQRSI 172
G GWVPSNY+TPVNSLEKHSWYHGP+SR+AAEYLLSS INGSFLVRESESSPGQ SI
Sbjct: 151 KNGQ-GWVPSNYITPVNSLEKHSWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSI 209
Query: 173 SLRYEGRVYHYRINEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKP 232
SLRYEGRVYHYRIN ADGKVYVT+ES+F TLAELVHHHS DGL+T L YPAPK +KP
Sbjct: 210 SLRYEGRVYHYRINTTADGKVYVTAESRFSTLAELVHHHSTVADGLVTTLHYPAPKCNKP 269
Query: 233 TVFPLAP-PDHWEIDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDF 291
TV+ ++P D WE++RTDI MKHKLGGGQYG+VY WK+ ++TVAVKTLK+DTM +++F
Sbjct: 270 TVYGVSPIHDKWEMERTDITMKHKLGGGQYGEVYVGVWKKYSLTVAVKTLKEDTMEVEEF 329
Query: 292 LEEASIMKEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMY 351
L+EA++MKE++HPNLVQLLGVCT EPPFYI+TE+M GNLL+YLR RE V AVVL+Y
Sbjct: 330 LKEAAVMKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLRECNREEVT-AVVLLY 388
Query: 352 MATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFP 411
MATQI+S M YLE ++FIHRDLAARNCLVGENH+VKVADFGL+RLM DTYTAHAGAKFP
Sbjct: 389 MATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLMTGDTYTAHAGAKFP 448
Query: 412 IKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
IKWTAPE LAYNTFS KSDVWAFG+LLWEIATYGMSPYPG+DL+ VY +LEK
Sbjct: 449 IKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEK 500
>AL359179-1|CAI15584.1| 1064|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1064
Score = 658 bits (1626), Expect = 0.0
Identities = 305/412 (74%), Positives = 354/412 (85%), Gaps = 4/412 (0%)
Query: 53 ANRWTSKENLLAHHEEDDPQLFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHT 112
A RW+SKENLL E DP LFVALYDF A G+N L++ KGE++R++ YN++GEW E +
Sbjct: 77 AIRWSSKENLLGA-TESDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNQNGEWSEVRS 135
Query: 113 LTGAVGWVPSNYVTPVNSLEKHSWYHGPISRNAAEYLLSSGINGSFLVRESESSPGQRSI 172
G GWVPSNY+TPVNSLEKHSWYHGP+SR+AAEYLLSS INGSFLVRESESSPGQ SI
Sbjct: 136 KNGQ-GWVPSNYITPVNSLEKHSWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSI 194
Query: 173 SLRYEGRVYHYRINEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKP 232
SLRYEGRVYHYRIN ADGKVYVT+ES+F TLAELVHHHS DGL+T L YPAPK +KP
Sbjct: 195 SLRYEGRVYHYRINTTADGKVYVTAESRFSTLAELVHHHSTVADGLVTTLHYPAPKCNKP 254
Query: 233 TVFPLAP-PDHWEIDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDF 291
TV+ ++P D WE++RTDI MKHKLGGGQYG+VY WK+ ++TVAVKTLK+DTM +++F
Sbjct: 255 TVYGVSPIHDKWEMERTDITMKHKLGGGQYGEVYVGVWKKYSLTVAVKTLKEDTMEVEEF 314
Query: 292 LEEASIMKEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMY 351
L+EA++MKE++HPNLVQLLGVCT EPPFYI+TE+M GNLL+YLR RE V AVVL+Y
Sbjct: 315 LKEAAVMKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLRECNREEVT-AVVLLY 373
Query: 352 MATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFP 411
MATQI+S M YLE ++FIHRDLAARNCLVGENH+VKVADFGL+RLM DTYTAHAGAKFP
Sbjct: 374 MATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLMTGDTYTAHAGAKFP 433
Query: 412 IKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
IKWTAPE LAYNTFS KSDVWAFG+LLWEIATYGMSPYPG+DL+ VY +LEK
Sbjct: 434 IKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEK 485
>AL139132-5|CAH70925.1| 1182|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1182
Score = 658 bits (1626), Expect = 0.0
Identities = 305/412 (74%), Positives = 354/412 (85%), Gaps = 4/412 (0%)
Query: 53 ANRWTSKENLLAHHEEDDPQLFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHT 112
A RW+SKENLL E DP LFVALYDF A G+N L++ KGE++R++ YN++GEW E +
Sbjct: 92 AIRWSSKENLLGA-TESDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNQNGEWSEVRS 150
Query: 113 LTGAVGWVPSNYVTPVNSLEKHSWYHGPISRNAAEYLLSSGINGSFLVRESESSPGQRSI 172
G GWVPSNY+TPVNSLEKHSWYHGP+SR+AAEYLLSS INGSFLVRESESSPGQ SI
Sbjct: 151 KNGQ-GWVPSNYITPVNSLEKHSWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSI 209
Query: 173 SLRYEGRVYHYRINEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKP 232
SLRYEGRVYHYRIN ADGKVYVT+ES+F TLAELVHHHS DGL+T L YPAPK +KP
Sbjct: 210 SLRYEGRVYHYRINTTADGKVYVTAESRFSTLAELVHHHSTVADGLVTTLHYPAPKCNKP 269
Query: 233 TVFPLAP-PDHWEIDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDF 291
TV+ ++P D WE++RTDI MKHKLGGGQYG+VY WK+ ++TVAVKTLK+DTM +++F
Sbjct: 270 TVYGVSPIHDKWEMERTDITMKHKLGGGQYGEVYVGVWKKYSLTVAVKTLKEDTMEVEEF 329
Query: 292 LEEASIMKEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMY 351
L+EA++MKE++HPNLVQLLGVCT EPPFYI+TE+M GNLL+YLR RE V AVVL+Y
Sbjct: 330 LKEAAVMKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLRECNREEVT-AVVLLY 388
Query: 352 MATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFP 411
MATQI+S M YLE ++FIHRDLAARNCLVGENH+VKVADFGL+RLM DTYTAHAGAKFP
Sbjct: 389 MATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLMTGDTYTAHAGAKFP 448
Query: 412 IKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
IKWTAPE LAYNTFS KSDVWAFG+LLWEIATYGMSPYPG+DL+ VY +LEK
Sbjct: 449 IKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEK 500
>AL139132-1|CAH70921.1| 1064|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1064
Score = 658 bits (1626), Expect = 0.0
Identities = 305/412 (74%), Positives = 354/412 (85%), Gaps = 4/412 (0%)
Query: 53 ANRWTSKENLLAHHEEDDPQLFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHT 112
A RW+SKENLL E DP LFVALYDF A G+N L++ KGE++R++ YN++GEW E +
Sbjct: 77 AIRWSSKENLLGA-TESDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNQNGEWSEVRS 135
Query: 113 LTGAVGWVPSNYVTPVNSLEKHSWYHGPISRNAAEYLLSSGINGSFLVRESESSPGQRSI 172
G GWVPSNY+TPVNSLEKHSWYHGP+SR+AAEYLLSS INGSFLVRESESSPGQ SI
Sbjct: 136 KNGQ-GWVPSNYITPVNSLEKHSWYHGPVSRSAAEYLLSSLINGSFLVRESESSPGQLSI 194
Query: 173 SLRYEGRVYHYRINEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKP 232
SLRYEGRVYHYRIN ADGKVYVT+ES+F TLAELVHHHS DGL+T L YPAPK +KP
Sbjct: 195 SLRYEGRVYHYRINTTADGKVYVTAESRFSTLAELVHHHSTVADGLVTTLHYPAPKCNKP 254
Query: 233 TVFPLAP-PDHWEIDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDF 291
TV+ ++P D WE++RTDI MKHKLGGGQYG+VY WK+ ++TVAVKTLK+DTM +++F
Sbjct: 255 TVYGVSPIHDKWEMERTDITMKHKLGGGQYGEVYVGVWKKYSLTVAVKTLKEDTMEVEEF 314
Query: 292 LEEASIMKEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMY 351
L+EA++MKE++HPNLVQLLGVCT EPPFYI+TE+M GNLL+YLR RE V AVVL+Y
Sbjct: 315 LKEAAVMKEIKHPNLVQLLGVCTLEPPFYIVTEYMPYGNLLDYLRECNREEVT-AVVLLY 373
Query: 352 MATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFP 411
MATQI+S M YLE ++FIHRDLAARNCLVGENH+VKVADFGL+RLM DTYTAHAGAKFP
Sbjct: 374 MATQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLMTGDTYTAHAGAKFP 433
Query: 412 IKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
IKWTAPE LAYNTFS KSDVWAFG+LLWEIATYGMSPYPG+DL+ VY +LEK
Sbjct: 434 IKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEK 485
>AB209642-1|BAD92879.1| 949|Homo sapiens Proto-oncogene
tyrosine-protein kinase ABL1 variant protein.
Length = 949
Score = 354 bits (870), Expect = 4e-97
Identities = 161/207 (77%), Positives = 186/207 (89%), Gaps = 1/207 (0%)
Query: 257 GGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASIMKEMRHPNLVQLLGVCTRE 316
GGGQYG+VYE WK+ ++TVAVKTLK+DTM +++FL+EA++MKE++HPNLVQLLGVCTRE
Sbjct: 68 GGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTRE 127
Query: 317 PPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIASGMSYLESRSFIHRDLAAR 376
PPFYIITEFM+ GNLL+YLR R+ V AVVL+YMATQI+S M YLE ++FIHRDLAAR
Sbjct: 128 PPFYIITEFMTYGNLLDYLRECNRQEV-NAVVLLYMATQISSAMEYLEKKNFIHRDLAAR 186
Query: 377 NCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEGLAYNTFSTKSDVWAFGI 436
NCLVGENHLVKVADFGL+RLM DTYTAHAGAKFPIKWTAPE LAYN FS KSDVWAFG+
Sbjct: 187 NCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGV 246
Query: 437 LLWEIATYGMSPYPGVDLADVYHMLEK 463
LLWEIATYGMSPYPG+DL+ VY +LEK
Sbjct: 247 LLWEIATYGMSPYPGIDLSQVYELLEK 273
>Z97989-4|CAI22300.1| 537|Homo sapiens FYN oncogene related to SRC,
FGR, YES protein.
Length = 537
Score = 353 bits (867), Expect = 1e-96
Identities = 184/400 (46%), Positives = 263/400 (65%), Gaps = 13/400 (3%)
Query: 73 LFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTLT-GAVGWVPSNYVTPVNSL 131
LFVALYD++A E+ L+ KGE+ +I++ + G+W EA +LT G G++PSNYV PV+S+
Sbjct: 86 LFVALYDYEARTEDDLSFHKGEKFQILN-SSEGDWWEARSLTTGETGYIPSNYVAPVDSI 144
Query: 132 EKHSWYHGPISRNAAE-YLLSSGI-NGSFLVRESESSPGQRSISLR----YEG-RVYHYR 184
+ WY G + R AE LLS G G+FL+RESE++ G S+S+R +G V HY+
Sbjct: 145 QAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGDHVKHYK 204
Query: 185 INEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPK-RSKPTVFPLAPPDHW 243
I + +G Y+T+ ++F TL +LV H+S GL +L+ P K + T + D W
Sbjct: 205 IRKLDNGGYYITTRAQFETLQQLVQHYSERAAGLCCRLVVPCHKGMPRLTDLSVKTKDVW 264
Query: 244 EIDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASIMKEMRH 303
EI R + + +LG GQ+G+V+ W GN VA+KTLK TM+ + FLEEA IMK+++H
Sbjct: 265 EIPRESLQLIKRLGNGQFGEVWMGTWN-GNTKVAIKTLKPGTMSPESFLEEAQIMKKLKH 323
Query: 304 PNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIASGMSYL 363
LVQL V + EP YI+TE+M++G+LL++L+ G + L+ MA Q+A+GM+Y+
Sbjct: 324 DKLVQLYAVVSEEP-IYIVTEYMNKGSLLDFLKDGEGRALK-LPNLVDMAAQVAAGMAYI 381
Query: 364 ESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEGLAYN 423
E ++IHRDL + N LVG + K+ADFGLARL+ D+ YTA GAKFPIKWTAPE Y
Sbjct: 382 ERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYG 441
Query: 424 TFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
F+ KSDVW+FGILL E+ T G PYPG++ +V +E+
Sbjct: 442 RFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVER 481
>M14333-1|AAC08285.1| 537|Homo sapiens protein ( Homo sapiens c-syn
protooncogene mRNA, complete cds. ).
Length = 537
Score = 353 bits (867), Expect = 1e-96
Identities = 184/400 (46%), Positives = 263/400 (65%), Gaps = 13/400 (3%)
Query: 73 LFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTLT-GAVGWVPSNYVTPVNSL 131
LFVALYD++A E+ L+ KGE+ +I++ + G+W EA +LT G G++PSNYV PV+S+
Sbjct: 86 LFVALYDYEARTEDDLSFHKGEKFQILN-SSEGDWWEARSLTTGETGYIPSNYVAPVDSI 144
Query: 132 EKHSWYHGPISRNAAE-YLLSSGI-NGSFLVRESESSPGQRSISLR----YEG-RVYHYR 184
+ WY G + R AE LLS G G+FL+RESE++ G S+S+R +G V HY+
Sbjct: 145 QAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGDHVKHYK 204
Query: 185 INEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPK-RSKPTVFPLAPPDHW 243
I + +G Y+T+ ++F TL +LV H+S GL +L+ P K + T + D W
Sbjct: 205 IRKLDNGGYYITTRAQFETLQQLVQHYSERAAGLCCRLVVPCHKGMPRLTDLSVKTKDVW 264
Query: 244 EIDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASIMKEMRH 303
EI R + + +LG GQ+G+V+ W GN VA+KTLK TM+ + FLEEA IMK+++H
Sbjct: 265 EIPRESLQLIKRLGNGQFGEVWMGTWN-GNTKVAIKTLKPGTMSPESFLEEAQIMKKLKH 323
Query: 304 PNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIASGMSYL 363
LVQL V + EP YI+TE+M++G+LL++L+ G + L+ MA Q+A+GM+Y+
Sbjct: 324 DKLVQLYAVVSEEP-IYIVTEYMNKGSLLDFLKDGEGRALK-LPNLVDMAAQVAAGMAYI 381
Query: 364 ESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEGLAYN 423
E ++IHRDL + N LVG + K+ADFGLARL+ D+ YTA GAKFPIKWTAPE Y
Sbjct: 382 ERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYG 441
Query: 424 TFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
F+ KSDVW+FGILL E+ T G PYPG++ +V +E+
Sbjct: 442 RFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVER 481
>M14676-1|AAA36615.1| 537|Homo sapiens protein ( Human src-like
kinase (slk) mRNA, complete cds. ).
Length = 537
Score = 352 bits (866), Expect = 1e-96
Identities = 184/400 (46%), Positives = 263/400 (65%), Gaps = 13/400 (3%)
Query: 73 LFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTLT-GAVGWVPSNYVTPVNSL 131
LFVALYD++A E+ L+ KGE+ +I++ + G+W EA +LT G G++PSNYV PV+S+
Sbjct: 86 LFVALYDYEARTEDDLSFHKGEKFQILN-SSEGDWWEARSLTTGETGYIPSNYVAPVDSI 144
Query: 132 EKHSWYHGPISRNAAE-YLLSSGI-NGSFLVRESESSPGQRSISLR----YEG-RVYHYR 184
+ WY G + R AE LLS G G+FL+RESE++ G S+S+R +G V HY+
Sbjct: 145 QAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGSYSLSIRDWDDMKGDHVKHYK 204
Query: 185 INEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPK-RSKPTVFPLAPPDHW 243
I + +G Y+T+ ++F TL +LV H+S GL +L+ P K + T + D W
Sbjct: 205 IRKLDNGGYYITTRAQFETLQQLVQHYSERAAGLCCRLVVPCHKGMPRLTDLSVKTKDVW 264
Query: 244 EIDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASIMKEMRH 303
EI R + + +LG GQ+G+V+ W GN VA+KTLK TM+ + FLEEA IMK+++H
Sbjct: 265 EIPRESLQLIKRLGNGQFGEVWMGTWN-GNTKVAIKTLKPGTMSPESFLEEAQIMKKLKH 323
Query: 304 PNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIASGMSYL 363
LVQL V + EP YI+TE+M++G+LL++L+ G + L+ MA Q+A+GM+Y+
Sbjct: 324 DKLVQLYAVVSEEP-IYIVTEYMNKGSLLDFLKDGEGRALK-LPNLVDMAAQVAAGMAYI 381
Query: 364 ESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEGLAYN 423
E ++IHRDL + N LVG + K+ADFGLARL+ D+ YTA GAKFPIKWTAPE Y
Sbjct: 382 ERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPERALYG 441
Query: 424 TFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
F+ KSDVW+FGILL E+ T G PYPG++ +V +E+
Sbjct: 442 RFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVER 481
>K03218-1|AAA60584.1| 536|Homo sapiens SRC protein.
Length = 536
Score = 347 bits (852), Expect = 7e-95
Identities = 187/398 (46%), Positives = 261/398 (65%), Gaps = 14/398 (3%)
Query: 74 FVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTL-TGAVGWVPSNYVTPVNSLE 132
FVALYD+++ E L+ KKGE+++I++ N G+W AH+L TG G++PSNYV P +S++
Sbjct: 89 FVALYDYESRTETDLSFKKGERLQIVN-NTEGDWWLAHSLSTGQTGYIPSNYVAPSDSIQ 147
Query: 133 KHSWYHGPISRNAAEYLLSSGIN--GSFLVRESESSPGQRSISL----RYEG-RVYHYRI 185
WY G I+R +E LL + N G+FLVRESE++ G +S+ +G V HY+I
Sbjct: 148 AEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKI 207
Query: 186 NEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKPTVFPLAPPDHWEI 245
+ G Y+TS ++F +L +LV ++S DGL +L P SKP LA D WEI
Sbjct: 208 RKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPT-SKPQTQGLAK-DAWEI 265
Query: 246 DRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASIMKEMRHPN 305
R + ++ KLG G +G+V+ W G VA+KTLK TM+ + FL+EA +MK++RH
Sbjct: 266 PRESLRLEVKLGQGCFGEVWMGTWN-GTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEK 324
Query: 306 LVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIASGMSYLES 365
LVQL V + EP YI+TE+MS+G+LL++L+ + + L+ MA QIASGM+Y+E
Sbjct: 325 LVQLYAVVSEEP-IYIVTEYMSKGSLLDFLKGETGKYLR-LPQLVDMAAQIASGMAYVER 382
Query: 366 RSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEGLAYNTF 425
+++HRDL A N LVGEN + KVADFGLARL+ D+ YTA GAKFPIKWTAPE Y F
Sbjct: 383 MNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRF 442
Query: 426 STKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
+ KSDVW+FGILL E+ T G PYPG+ +V +E+
Sbjct: 443 TIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVER 480
>BC051270-1|AAH51270.2| 536|Homo sapiens v-src sarcoma
(Schmidt-Ruppin A-2) viral oncogene homolog (avian)
protein.
Length = 536
Score = 347 bits (852), Expect = 7e-95
Identities = 187/398 (46%), Positives = 261/398 (65%), Gaps = 14/398 (3%)
Query: 74 FVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTL-TGAVGWVPSNYVTPVNSLE 132
FVALYD+++ E L+ KKGE+++I++ N G+W AH+L TG G++PSNYV P +S++
Sbjct: 89 FVALYDYESRTETDLSFKKGERLQIVN-NTEGDWWLAHSLSTGQTGYIPSNYVAPSDSIQ 147
Query: 133 KHSWYHGPISRNAAEYLLSSGIN--GSFLVRESESSPGQRSISL----RYEG-RVYHYRI 185
WY G I+R +E LL + N G+FLVRESE++ G +S+ +G V HY+I
Sbjct: 148 AEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKI 207
Query: 186 NEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKPTVFPLAPPDHWEI 245
+ G Y+TS ++F +L +LV ++S DGL +L P SKP LA D WEI
Sbjct: 208 RKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPT-SKPQTQGLAK-DAWEI 265
Query: 246 DRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASIMKEMRHPN 305
R + ++ KLG G +G+V+ W G VA+KTLK TM+ + FL+EA +MK++RH
Sbjct: 266 PRESLRLEVKLGQGCFGEVWMGTWN-GTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEK 324
Query: 306 LVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIASGMSYLES 365
LVQL V + EP YI+TE+MS+G+LL++L+ + + L+ MA QIASGM+Y+E
Sbjct: 325 LVQLYAVVSEEP-IYIVTEYMSKGSLLDFLKGETGKYLR-LPQLVDMAAQIASGMAYVER 382
Query: 366 RSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEGLAYNTF 425
+++HRDL A N LVGEN + KVADFGLARL+ D+ YTA GAKFPIKWTAPE Y F
Sbjct: 383 MNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRF 442
Query: 426 STKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
+ KSDVW+FGILL E+ T G PYPG+ +V +E+
Sbjct: 443 TIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVER 480
>BC011566-1|AAH11566.1| 536|Homo sapiens SRC protein protein.
Length = 536
Score = 347 bits (852), Expect = 7e-95
Identities = 187/398 (46%), Positives = 261/398 (65%), Gaps = 14/398 (3%)
Query: 74 FVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTL-TGAVGWVPSNYVTPVNSLE 132
FVALYD+++ E L+ KKGE+++I++ N G+W AH+L TG G++PSNYV P +S++
Sbjct: 89 FVALYDYESRTETDLSFKKGERLQIVN-NTEGDWWLAHSLSTGQTGYIPSNYVAPSDSIQ 147
Query: 133 KHSWYHGPISRNAAEYLLSSGIN--GSFLVRESESSPGQRSISL----RYEG-RVYHYRI 185
WY G I+R +E LL + N G+FLVRESE++ G +S+ +G V HY+I
Sbjct: 148 AEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKI 207
Query: 186 NEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKPTVFPLAPPDHWEI 245
+ G Y+TS ++F +L +LV ++S DGL +L P SKP LA D WEI
Sbjct: 208 RKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPT-SKPQTQGLAK-DAWEI 265
Query: 246 DRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASIMKEMRHPN 305
R + ++ KLG G +G+V+ W G VA+KTLK TM+ + FL+EA +MK++RH
Sbjct: 266 PRESLRLEVKLGQGCFGEVWMGTWN-GTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEK 324
Query: 306 LVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIASGMSYLES 365
LVQL V + EP YI+TE+MS+G+LL++L+ + + L+ MA QIASGM+Y+E
Sbjct: 325 LVQLYAVVSEEP-IYIVTEYMSKGSLLDFLKGETGKYLR-LPQLVDMAAQIASGMAYVER 382
Query: 366 RSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEGLAYNTF 425
+++HRDL A N LVGEN + KVADFGLARL+ D+ YTA GAKFPIKWTAPE Y F
Sbjct: 383 MNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRF 442
Query: 426 STKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
+ KSDVW+FGILL E+ T G PYPG+ +V +E+
Sbjct: 443 TIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVER 480
>AL133293-1|CAC34523.1| 536|Homo sapiens v-src sarcoma
(Schmidt-Ruppin A-2) viral oncogenem exchanger), member
2 protein.
Length = 536
Score = 347 bits (852), Expect = 7e-95
Identities = 187/398 (46%), Positives = 261/398 (65%), Gaps = 14/398 (3%)
Query: 74 FVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTL-TGAVGWVPSNYVTPVNSLE 132
FVALYD+++ E L+ KKGE+++I++ N G+W AH+L TG G++PSNYV P +S++
Sbjct: 89 FVALYDYESRTETDLSFKKGERLQIVN-NTEGDWWLAHSLSTGQTGYIPSNYVAPSDSIQ 147
Query: 133 KHSWYHGPISRNAAEYLLSSGIN--GSFLVRESESSPGQRSISL----RYEG-RVYHYRI 185
WY G I+R +E LL + N G+FLVRESE++ G +S+ +G V HY+I
Sbjct: 148 AEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKI 207
Query: 186 NEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKPTVFPLAPPDHWEI 245
+ G Y+TS ++F +L +LV ++S DGL +L P SKP LA D WEI
Sbjct: 208 RKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPT-SKPQTQGLAK-DAWEI 265
Query: 246 DRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASIMKEMRHPN 305
R + ++ KLG G +G+V+ W G VA+KTLK TM+ + FL+EA +MK++RH
Sbjct: 266 PRESLRLEVKLGQGCFGEVWMGTWN-GTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEK 324
Query: 306 LVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIASGMSYLES 365
LVQL V + EP YI+TE+MS+G+LL++L+ + + L+ MA QIASGM+Y+E
Sbjct: 325 LVQLYAVVSEEP-IYIVTEYMSKGSLLDFLKGETGKYLR-LPQLVDMAAQIASGMAYVER 382
Query: 366 RSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEGLAYNTF 425
+++HRDL A N LVGEN + KVADFGLARL+ D+ YTA GAKFPIKWTAPE Y F
Sbjct: 383 MNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRF 442
Query: 426 STKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
+ KSDVW+FGILL E+ T G PYPG+ +V +E+
Sbjct: 443 TIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVER 480
>Z97989-5|CAI22301.1| 534|Homo sapiens FYN oncogene related to SRC,
FGR, YES protein.
Length = 534
Score = 346 bits (851), Expect = 9e-95
Identities = 184/399 (46%), Positives = 261/399 (65%), Gaps = 14/399 (3%)
Query: 73 LFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTLT-GAVGWVPSNYVTPVNSL 131
LFVALYD++A E+ L+ KGE+ +I++ + G+W EA +LT G G++PSNYV PV+S+
Sbjct: 86 LFVALYDYEARTEDDLSFHKGEKFQILN-SSEGDWWEARSLTTGETGYIPSNYVAPVDSI 144
Query: 132 EKHSWYHGPISRNAAE-YLLSSGI-NGSFLVRESESSPGQRSISLR----YEG-RVYHYR 184
+ WY G + R AE LLS G G+FL+RESE++ G S+S+R +G V HY+
Sbjct: 145 QAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGDHVKHYK 204
Query: 185 INEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKPTVFPLAPPDHWE 244
I + +G Y+T+ ++F TL +LV H+S DGL L A + P LA D WE
Sbjct: 205 IRKLDNGGYYITTRAQFETLQQLVQHYSEKADGLCFNLTVIASSCT-PQTSGLAK-DAWE 262
Query: 245 IDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASIMKEMRHP 304
+ R + ++ KLG G + +V+ W GN VA+KTLK TM+ + FLEEA IMK+++H
Sbjct: 263 VARRSLCLEKKLGQGCFAEVWLGTWN-GNTKVAIKTLKPGTMSPESFLEEAQIMKKLKHD 321
Query: 305 NLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIASGMSYLE 364
LVQL V + EP YI+TE+M++G+LL++L+ G + L+ MA Q+A+GM+Y+E
Sbjct: 322 KLVQLYAVVSEEP-IYIVTEYMNKGSLLDFLKDGEGRALK-LPNLVDMAAQVAAGMAYIE 379
Query: 365 SRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEGLAYNT 424
++IHRDL + N LVG + K+ADFGLARL+ D+ YTA GAKFPIKWTAPE Y
Sbjct: 380 RMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGR 439
Query: 425 FSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
F+ KSDVW+FGILL E+ T G PYPG++ +V +E+
Sbjct: 440 FTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVER 478
>S74774-1|AAB33113.2| 534|Homo sapiens tyrosine kinase p59fyn(T)
protein.
Length = 534
Score = 345 bits (849), Expect = 2e-94
Identities = 184/399 (46%), Positives = 261/399 (65%), Gaps = 14/399 (3%)
Query: 73 LFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTLT-GAVGWVPSNYVTPVNSL 131
LFVALYD++A E+ L+ KGE+ +I++ + G+W EA +LT G G++PSNYV PV+S+
Sbjct: 86 LFVALYDYEARTEDDLSFHKGEKFQILN-SSEGDWWEARSLTTGETGYIPSNYVAPVDSI 144
Query: 132 EKHSWYHGPISRNAAE-YLLSSGI-NGSFLVRESESSPGQRSISLR----YEG-RVYHYR 184
+ WY G + R AE LLS G G+FL+RESE++ G S+S+R +G V HY+
Sbjct: 145 QAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGDHVKHYK 204
Query: 185 INEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKPTVFPLAPPDHWE 244
I + +G Y+T+ ++F TL +LV H+S DGL L A + P LA D WE
Sbjct: 205 IRKLDNGGYYITTRAQFETLQQLVQHYSEKADGLCFNLTVIASSCT-PQTSGLAK-DAWE 262
Query: 245 IDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASIMKEMRHP 304
+ R + ++ KLG G + +V+ W GN VA+KTLK TM+ + FLEEA IMK+++H
Sbjct: 263 VARRSLCLEKKLGQGCFAEVWLGTWN-GNTKVAIKTLKPGTMSPESFLEEAQIMKKLKHD 321
Query: 305 NLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIASGMSYLE 364
LVQL V + EP YI+TE+M++G+LL++L+ G + L+ MA Q+A+GM+Y+E
Sbjct: 322 KLVQLYAVVSEEP-IYIVTEYMNKGSLLDFLKDGEGRALK-LPNLVDMAAQVAAGMAYIE 379
Query: 365 SRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEGLAYNT 424
++IHRDL + N LVG + K+ADFGLARL+ D+ YTA GAKFPIKWTAPE Y
Sbjct: 380 RMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPERALYGR 439
Query: 425 FSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
F+ KSDVW+FGILL E+ T G PYPG++ +V +E+
Sbjct: 440 FTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVER 478
>M19722-1|AAA52451.1| 529|Homo sapiens FGR protein.
Length = 529
Score = 343 bits (842), Expect = 1e-93
Identities = 186/399 (46%), Positives = 252/399 (63%), Gaps = 14/399 (3%)
Query: 73 LFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTLT-GAVGWVPSNYVTPVNSL 131
LF+ALYD++A E+ LT KGE+ I++ N G+W EA +L+ G G +PSNYV PV+S+
Sbjct: 81 LFIALYDYEARTEDDLTFTKGEKFHILN-NTEGDWWEARSLSSGKTGCIPSNYVAPVDSI 139
Query: 132 EKHSWYHGPISRNAAE-YLLSSGI-NGSFLVRESESSPGQRSISLR-----YEGRVYHYR 184
+ WY G I R AE LLS G G+FL+RESE++ G S+S+R V HY+
Sbjct: 140 QAEEWYFGKIGRKDAERQLLSPGNPQGAFLIRESETTKGAYSLSIRDWDQTRGDHVKHYK 199
Query: 185 INEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKPTVFPLAPPDHWE 244
I + G Y+T+ +F ++ ELV H+ DGL L+ P KP LA D WE
Sbjct: 200 IRKLDMGGYYITTRVQFNSVQELVQHYMEVNDGLCNLLIAPCTIM-KPQTLGLAK-DAWE 257
Query: 245 IDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASIMKEMRHP 304
I R+ I ++ +LG G +GDV+ W G+ VAVKTLK TM+ K FLEEA +MK +RH
Sbjct: 258 ISRSSITLERRLGTGCFGDVWLGTWN-GSTKVAVKTLKPGTMSPKAFLEEAQVMKLLRHD 316
Query: 305 NLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIASGMSYLE 364
LVQL V + EP YI+TEFM G+LL++L+ + + L+ MA Q+A GM+Y+E
Sbjct: 317 KLVQLYAVVSEEP-IYIVTEFMCHGSLLDFLKNPEGQDLR-LPQLVDMAAQVAEGMAYME 374
Query: 365 SRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEGLAYNT 424
++IHRDL A N LVGE K+ADFGLARL++DD Y G+KFPIKWTAPE +
Sbjct: 375 RMNYIHRDLRAANILVGERLACKIADFGLARLIKDDEYNPCQGSKFPIKWTAPEAALFGR 434
Query: 425 FSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
F+ KSDVW+FGILL E+ T G PYPG++ +V +E+
Sbjct: 435 FTIKSDVWSFGILLTELITKGRIPYPGMNKREVLEQVEQ 473
>BC064382-1|AAH64382.1| 529|Homo sapiens Gardner-Rasheed feline
sarcoma viral (v-fgr) oncogene homolog protein.
Length = 529
Score = 343 bits (842), Expect = 1e-93
Identities = 186/399 (46%), Positives = 252/399 (63%), Gaps = 14/399 (3%)
Query: 73 LFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTLT-GAVGWVPSNYVTPVNSL 131
LF+ALYD++A E+ LT KGE+ I++ N G+W EA +L+ G G +PSNYV PV+S+
Sbjct: 81 LFIALYDYEARTEDDLTFTKGEKFHILN-NTEGDWWEARSLSSGKTGCIPSNYVAPVDSI 139
Query: 132 EKHSWYHGPISRNAAE-YLLSSGI-NGSFLVRESESSPGQRSISLR-----YEGRVYHYR 184
+ WY G I R AE LLS G G+FL+RESE++ G S+S+R V HY+
Sbjct: 140 QAEEWYFGKIGRKDAERQLLSPGNPQGAFLIRESETTKGAYSLSIRDWDQTRGDHVKHYK 199
Query: 185 INEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKPTVFPLAPPDHWE 244
I + G Y+T+ +F ++ ELV H+ DGL L+ P KP LA D WE
Sbjct: 200 IRKLDMGGYYITTRVQFNSVQELVQHYMEVNDGLCNLLIAPCTIM-KPQTLGLAK-DAWE 257
Query: 245 IDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASIMKEMRHP 304
I R+ I ++ +LG G +GDV+ W G+ VAVKTLK TM+ K FLEEA +MK +RH
Sbjct: 258 ISRSSITLERRLGTGCFGDVWLGTWN-GSTKVAVKTLKPGTMSPKAFLEEAQVMKLLRHD 316
Query: 305 NLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIASGMSYLE 364
LVQL V + EP YI+TEFM G+LL++L+ + + L+ MA Q+A GM+Y+E
Sbjct: 317 KLVQLYAVVSEEP-IYIVTEFMCHGSLLDFLKNPEGQDLR-LPQLVDMAAQVAEGMAYME 374
Query: 365 SRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEGLAYNT 424
++IHRDL A N LVGE K+ADFGLARL++DD Y G+KFPIKWTAPE +
Sbjct: 375 RMNYIHRDLRAANILVGERLACKIADFGLARLIKDDEYNPCQGSKFPIKWTAPEAALFGR 434
Query: 425 FSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
F+ KSDVW+FGILL E+ T G PYPG++ +V +E+
Sbjct: 435 FTIKSDVWSFGILLTELITKGRIPYPGMNKREVLEQVEQ 473
>AL031729-3|CAB62998.1| 529|Homo sapiens Gardner-Rasheed feline
sarcoma viral (v-fgr) oncogene homolog protein.
Length = 529
Score = 343 bits (842), Expect = 1e-93
Identities = 186/399 (46%), Positives = 252/399 (63%), Gaps = 14/399 (3%)
Query: 73 LFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTLT-GAVGWVPSNYVTPVNSL 131
LF+ALYD++A E+ LT KGE+ I++ N G+W EA +L+ G G +PSNYV PV+S+
Sbjct: 81 LFIALYDYEARTEDDLTFTKGEKFHILN-NTEGDWWEARSLSSGKTGCIPSNYVAPVDSI 139
Query: 132 EKHSWYHGPISRNAAE-YLLSSGI-NGSFLVRESESSPGQRSISLR-----YEGRVYHYR 184
+ WY G I R AE LLS G G+FL+RESE++ G S+S+R V HY+
Sbjct: 140 QAEEWYFGKIGRKDAERQLLSPGNPQGAFLIRESETTKGAYSLSIRDWDQTRGDHVKHYK 199
Query: 185 INEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKPTVFPLAPPDHWE 244
I + G Y+T+ +F ++ ELV H+ DGL L+ P KP LA D WE
Sbjct: 200 IRKLDMGGYYITTRVQFNSVQELVQHYMEVNDGLCNLLIAPCTIM-KPQTLGLAK-DAWE 257
Query: 245 IDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASIMKEMRHP 304
I R+ I ++ +LG G +GDV+ W G+ VAVKTLK TM+ K FLEEA +MK +RH
Sbjct: 258 ISRSSITLERRLGTGCFGDVWLGTWN-GSTKVAVKTLKPGTMSPKAFLEEAQVMKLLRHD 316
Query: 305 NLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIASGMSYLE 364
LVQL V + EP YI+TEFM G+LL++L+ + + L+ MA Q+A GM+Y+E
Sbjct: 317 KLVQLYAVVSEEP-IYIVTEFMCHGSLLDFLKNPEGQDLR-LPQLVDMAAQVAEGMAYME 374
Query: 365 SRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEGLAYNT 424
++IHRDL A N LVGE K+ADFGLARL++DD Y G+KFPIKWTAPE +
Sbjct: 375 RMNYIHRDLRAANILVGERLACKIADFGLARLIKDDEYNPCQGSKFPIKWTAPEAALFGR 434
Query: 425 FSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
F+ KSDVW+FGILL E+ T G PYPG++ +V +E+
Sbjct: 435 FTIKSDVWSFGILLTELITKGRIPYPGMNKREVLEQVEQ 473
>M15990-1|AAA35735.1| 543|Homo sapiens protein ( Human c-yes-1
mRNA. ).
Length = 543
Score = 342 bits (841), Expect = 1e-93
Identities = 187/399 (46%), Positives = 256/399 (64%), Gaps = 14/399 (3%)
Query: 73 LFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTL-TGAVGWVPSNYVTPVNSL 131
+FVALYD++A L+ KKGE+ +I++ N G+W EA ++ TG G++PSNYV P +S+
Sbjct: 95 IFVALYDYEARTTEDLSFKKGERFQIIN-NTEGDWWEARSIATGKNGYIPSNYVAPADSI 153
Query: 132 EKHSWYHGPISRNAAEYLLSSGIN--GSFLVRESESSPGQRSISLR----YEG-RVYHYR 184
+ WY G + R AE LL + N G FLVRESE++ G S+S+R G V HY+
Sbjct: 154 QAEEWYFGKMGRKDAERLLLNPGNQRGIFLVRESETTKGAYSLSIRDWDEIRGDNVKHYK 213
Query: 185 INEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKPTVFPLAPPDHWE 244
I + +G Y+T+ ++F TL +LV H++ DGL +L P KP LA D WE
Sbjct: 214 IRKLDNGGYYITTRAQFDTLQKLVKHYTEHADGLCHKLTTVCPT-VKPQTQGLAK-DAWE 271
Query: 245 IDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASIMKEMRHP 304
I R + ++ KLG G +G+V+ W G VA+KTLK TM + FL+EA IMK++RH
Sbjct: 272 IPRESLRLEVKLGQGCFGEVWMGTWN-GTTKVAIKTLKPGTMMPEAFLQEAQIMKKLRHD 330
Query: 305 NLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIASGMSYLE 364
LV L V + EP YI+TEFMS+G+LL++L+ G + + L+ MA QIA GM+Y+E
Sbjct: 331 KLVPLYAVVSEEP-IYIVTEFMSKGSLLDFLKEGDGKYLK-LPQLVDMAAQIADGMAYIE 388
Query: 365 SRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEGLAYNT 424
++IHRDL A N LVGEN + K+ADFGLARL+ D+ YTA GAKFPIKWTAPE Y
Sbjct: 389 RMNYIHRDLRAANILVGENLVCKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGR 448
Query: 425 FSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
F+ KSDVW+FGIL E+ T G PYPG+ +V +E+
Sbjct: 449 FTIKSDVWSFGILQTELVTKGRVPYPGMVNREVLEQVER 487
>BC048960-1|AAH48960.1| 543|Homo sapiens v-yes-1 Yamaguchi sarcoma
viral oncogene homolog 1 protein.
Length = 543
Score = 342 bits (841), Expect = 1e-93
Identities = 187/399 (46%), Positives = 256/399 (64%), Gaps = 14/399 (3%)
Query: 73 LFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTL-TGAVGWVPSNYVTPVNSL 131
+FVALYD++A L+ KKGE+ +I++ N G+W EA ++ TG G++PSNYV P +S+
Sbjct: 95 IFVALYDYEARTTEDLSFKKGERFQIIN-NTEGDWWEARSIATGKNGYIPSNYVAPADSI 153
Query: 132 EKHSWYHGPISRNAAEYLLSSGIN--GSFLVRESESSPGQRSISLR----YEG-RVYHYR 184
+ WY G + R AE LL + N G FLVRESE++ G S+S+R G V HY+
Sbjct: 154 QAEEWYFGKMGRKDAERLLLNPGNQRGIFLVRESETTKGAYSLSIRDWDEIRGDNVKHYK 213
Query: 185 INEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKPTVFPLAPPDHWE 244
I + +G Y+T+ ++F TL +LV H++ DGL +L P KP LA D WE
Sbjct: 214 IRKLDNGGYYITTRAQFDTLQKLVKHYTEHADGLCHKLTTVCPT-VKPQTQGLAK-DAWE 271
Query: 245 IDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASIMKEMRHP 304
I R + ++ KLG G +G+V+ W G VA+KTLK TM + FL+EA IMK++RH
Sbjct: 272 IPRESLRLEVKLGQGCFGEVWMGTWN-GTTKVAIKTLKPGTMMPEAFLQEAQIMKKLRHD 330
Query: 305 NLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIASGMSYLE 364
LV L V + EP YI+TEFMS+G+LL++L+ G + + L+ MA QIA GM+Y+E
Sbjct: 331 KLVPLYAVVSEEP-IYIVTEFMSKGSLLDFLKEGDGKYLK-LPQLVDMAAQIADGMAYIE 388
Query: 365 SRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEGLAYNT 424
++IHRDL A N LVGEN + K+ADFGLARL+ D+ YTA GAKFPIKWTAPE Y
Sbjct: 389 RMNYIHRDLRAANILVGENLVCKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGR 448
Query: 425 FSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
F+ KSDVW+FGIL E+ T G PYPG+ +V +E+
Sbjct: 449 FTIKSDVWSFGILQTELVTKGRVPYPGMVNREVLEQVER 487
>AL133293-2|CAC10573.1| 542|Homo sapiens v-src sarcoma
(Schmidt-Ruppin A-2) viral oncogenem exchanger), member
2 protein.
Length = 542
Score = 341 bits (839), Expect = 3e-93
Identities = 186/403 (46%), Positives = 261/403 (64%), Gaps = 18/403 (4%)
Query: 74 FVALYDFQAGGENQLTLKKGEQVRIMSYNKS-----GEWCEAHTL-TGAVGWVPSNYVTP 127
FVALYD+++ E L+ KKGE+++I++ + G+W AH+L TG G++PSNYV P
Sbjct: 89 FVALYDYESRTETDLSFKKGERLQIVNNTRKVDVREGDWWLAHSLSTGQTGYIPSNYVAP 148
Query: 128 VNSLEKHSWYHGPISRNAAEYLLSSGIN--GSFLVRESESSPGQRSISL----RYEG-RV 180
+S++ WY G I+R +E LL + N G+FLVRESE++ G +S+ +G V
Sbjct: 149 SDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNV 208
Query: 181 YHYRINEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKPTVFPLAPP 240
HY+I + G Y+TS ++F +L +LV ++S DGL +L P SKP LA
Sbjct: 209 KHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPT-SKPQTQGLAK- 266
Query: 241 DHWEIDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASIMKE 300
D WEI R + ++ KLG G +G+V+ W G VA+KTLK TM+ + FL+EA +MK+
Sbjct: 267 DAWEIPRESLRLEVKLGQGCFGEVWMGTWN-GTTRVAIKTLKPGTMSPEAFLQEAQVMKK 325
Query: 301 MRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIASGM 360
+RH LVQL V + EP YI+TE+MS+G+LL++L+ + + L+ MA QIASGM
Sbjct: 326 LRHEKLVQLYAVVSEEP-IYIVTEYMSKGSLLDFLKGETGKYLR-LPQLVDMAAQIASGM 383
Query: 361 SYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEGL 420
+Y+E +++HRDL A N LVGEN + KVADFGLARL+ D+ YTA GAKFPIKWTAPE
Sbjct: 384 AYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAA 443
Query: 421 AYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
Y F+ KSDVW+FGILL E+ T G PYPG+ +V +E+
Sbjct: 444 LYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVER 486
>U22322-1|AAC50116.1| 505|Homo sapiens Rak protein.
Length = 505
Score = 337 bits (828), Expect = 5e-92
Identities = 184/402 (45%), Positives = 240/402 (59%), Gaps = 16/402 (3%)
Query: 74 FVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAH-------TLTGAVGWVPSNYVT 126
FVAL+D+QA L+ + G++++++ G W H + G++PSNYV
Sbjct: 47 FVALFDYQARTAEDLSFRAGDKLQVLDTLHEGWWFARHLEKRRDGSSQQLQGYIPSNYVA 106
Query: 127 PVNSLEKHSWYHGPISRNAAE--YLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYR 184
SL+ +W+ G I R+ AE L S GSFL+RESES G+ S+S+ V HYR
Sbjct: 107 EDRSLQAEAWFFGAIRRSDAEKQLLYSENKTGSFLIRESESQKGEFSLSVLDGAVVKHYR 166
Query: 185 INEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKPTVFPLA--PPDH 242
I +G ++T F TL E V H++ DGL +L P K P F L+ D
Sbjct: 167 IKRLDEGGFFLTRRRIFSTLNEFVSHYTKTSDGLCVKLGKPCLKIQVPAPFDLSYKTVDQ 226
Query: 243 WEIDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASIMKEMR 302
WEIDR I + +LG GQ+G+V+E W VAVKTLK +M DFL EA IMK +R
Sbjct: 227 WEIDRNSIQLLKRLGSGQFGEVWEGLWNN-TTPVAVKTLKPGSMDPNDFLREAQIMKNLR 285
Query: 303 HPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIASGMSY 362
HP L+QL VCT E P YIITE M G+L EYL+ + + MA Q+ASGM+Y
Sbjct: 286 HPKLIQLYAVCTLEDPIYIITELMRHGSLQEYLQNDTGSKI-HLTQQVDMAAQVASGMAY 344
Query: 363 LESRSFIHRDLAARNCLVGENHLVKVADFGLARLMR---DDTYTAHAGAKFPIKWTAPEG 419
LESR++IHRDLAARN LVGE+++ KVADFGLAR+ + +D Y + K P+KWTAPE
Sbjct: 345 LESRNYIHRDLAARNVLVGEHNIYKVADFGLARVFKVDNEDIYESRHEIKLPVKWTAPEA 404
Query: 420 LAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHML 461
+ N FS KSDVW+FGILL+EI TYG PY G+ A V ML
Sbjct: 405 IRSNKFSIKSDVWSFGILLYEIITYGKMPYSGMTGAQVIQML 446
>U00803-1|AAA18284.1| 505|Homo sapiens SRC-like tyrosine kinase
protein.
Length = 505
Score = 336 bits (827), Expect = 7e-92
Identities = 184/402 (45%), Positives = 239/402 (59%), Gaps = 16/402 (3%)
Query: 74 FVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAH-------TLTGAVGWVPSNYVT 126
FVAL+D+QA L+ + G++++++ G W H + G++PSNYV
Sbjct: 47 FVALFDYQARTAEDLSFRAGDKLQVLDTLHEGWWFARHLEKRRDGSSQQLQGYIPSNYVA 106
Query: 127 PVNSLEKHSWYHGPISRNAAE--YLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYR 184
SL+ W+ G I R+ AE L S GSFL+RESES G+ S+S+ V HYR
Sbjct: 107 EDRSLQAEPWFFGAIGRSDAEKQLLYSENKTGSFLIRESESQKGEFSLSVLDGAVVKHYR 166
Query: 185 INEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKPTVFPLA--PPDH 242
I +G ++T F TL E V H++ DGL +L P K P F L+ D
Sbjct: 167 IKRLDEGGFFLTRRRIFSTLNEFVSHYTKTSDGLCVKLGKPCLKIQVPAPFDLSYKTVDQ 226
Query: 243 WEIDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASIMKEMR 302
WEIDR I + +LG GQ+G+V+E W VAVKTLK +M DFL EA IMK +R
Sbjct: 227 WEIDRNSIQLLKRLGSGQFGEVWEGLWNN-TTPVAVKTLKPGSMDPNDFLREAQIMKNLR 285
Query: 303 HPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIASGMSY 362
HP L+QL VCT E P YIITE M G+L EYL+ + + MA Q+ASGM+Y
Sbjct: 286 HPKLIQLYAVCTLEDPIYIITELMRHGSLQEYLQNDTGSKI-HLTQQVDMAAQVASGMAY 344
Query: 363 LESRSFIHRDLAARNCLVGENHLVKVADFGLARLMR---DDTYTAHAGAKFPIKWTAPEG 419
LESR++IHRDLAARN LVGE+++ KVADFGLAR+ + +D Y + K P+KWTAPE
Sbjct: 345 LESRNYIHRDLAARNVLVGEHNIYKVADFGLARVFKVDNEDIYESRHEIKLPVKWTAPEA 404
Query: 420 LAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHML 461
+ N FS KSDVW+FGILL+EI TYG PY G+ A V ML
Sbjct: 405 IRSNKFSIKSDVWSFGILLYEIITYGKMPYSGMTGAQVIQML 446
>BC012916-1|AAH12916.1| 505|Homo sapiens fyn-related kinase
protein.
Length = 505
Score = 336 bits (827), Expect = 7e-92
Identities = 184/402 (45%), Positives = 239/402 (59%), Gaps = 16/402 (3%)
Query: 74 FVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAH-------TLTGAVGWVPSNYVT 126
FVAL+D+QA L+ + G++++++ G W H + G++PSNYV
Sbjct: 47 FVALFDYQARTAEDLSFRAGDKLQVLDTLHEGWWFARHLEKRRDGSSQQLQGYIPSNYVA 106
Query: 127 PVNSLEKHSWYHGPISRNAAE--YLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYR 184
SL+ W+ G I R+ AE L S GSFL+RESES G+ S+S+ V HYR
Sbjct: 107 EDRSLQAEPWFFGAIGRSDAEKQLLYSENKTGSFLIRESESQKGEFSLSVLDGAVVKHYR 166
Query: 185 INEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKPTVFPLA--PPDH 242
I +G ++T F TL E V H++ DGL +L P K P F L+ D
Sbjct: 167 IKRLDEGGFFLTRRRIFSTLNEFVSHYTKTSDGLCVKLGKPCLKIQVPAPFDLSYKTVDQ 226
Query: 243 WEIDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASIMKEMR 302
WEIDR I + +LG GQ+G+V+E W VAVKTLK +M DFL EA IMK +R
Sbjct: 227 WEIDRNSIQLLKRLGSGQFGEVWEGLWNN-TTPVAVKTLKPGSMDPNDFLREAQIMKNLR 285
Query: 303 HPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIASGMSY 362
HP L+QL VCT E P YIITE M G+L EYL+ + + MA Q+ASGM+Y
Sbjct: 286 HPKLIQLYAVCTLEDPIYIITELMRHGSLQEYLQNDTGSKI-HLTQQVDMAAQVASGMAY 344
Query: 363 LESRSFIHRDLAARNCLVGENHLVKVADFGLARLMR---DDTYTAHAGAKFPIKWTAPEG 419
LESR++IHRDLAARN LVGE+++ KVADFGLAR+ + +D Y + K P+KWTAPE
Sbjct: 345 LESRNYIHRDLAARNVLVGEHNIYKVADFGLARVFKVDNEDIYESRHEIKLPVKWTAPEA 404
Query: 420 LAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHML 461
+ N FS KSDVW+FGILL+EI TYG PY G+ A V ML
Sbjct: 405 IRSNKFSIKSDVWSFGILLYEIITYGKMPYSGMTGAQVIQML 446
>AL357141-2|CAI16469.1| 505|Homo sapiens fyn-related kinase
protein.
Length = 505
Score = 336 bits (827), Expect = 7e-92
Identities = 184/402 (45%), Positives = 239/402 (59%), Gaps = 16/402 (3%)
Query: 74 FVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAH-------TLTGAVGWVPSNYVT 126
FVAL+D+QA L+ + G++++++ G W H + G++PSNYV
Sbjct: 47 FVALFDYQARTAEDLSFRAGDKLQVLDTLHEGWWFARHLEKRRDGSSQQLQGYIPSNYVA 106
Query: 127 PVNSLEKHSWYHGPISRNAAE--YLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYR 184
SL+ W+ G I R+ AE L S GSFL+RESES G+ S+S+ V HYR
Sbjct: 107 EDRSLQAEPWFFGAIGRSDAEKQLLYSENKTGSFLIRESESQKGEFSLSVLDGAVVKHYR 166
Query: 185 INEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKPTVFPLA--PPDH 242
I +G ++T F TL E V H++ DGL +L P K P F L+ D
Sbjct: 167 IKRLDEGGFFLTRRRIFSTLNEFVSHYTKTSDGLCVKLGKPCLKIQVPAPFDLSYKTVDQ 226
Query: 243 WEIDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASIMKEMR 302
WEIDR I + +LG GQ+G+V+E W VAVKTLK +M DFL EA IMK +R
Sbjct: 227 WEIDRNSIQLLKRLGSGQFGEVWEGLWNN-TTPVAVKTLKPGSMDPNDFLREAQIMKNLR 285
Query: 303 HPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIASGMSY 362
HP L+QL VCT E P YIITE M G+L EYL+ + + MA Q+ASGM+Y
Sbjct: 286 HPKLIQLYAVCTLEDPIYIITELMRHGSLQEYLQNDTGSKI-HLTQQVDMAAQVASGMAY 344
Query: 363 LESRSFIHRDLAARNCLVGENHLVKVADFGLARLMR---DDTYTAHAGAKFPIKWTAPEG 419
LESR++IHRDLAARN LVGE+++ KVADFGLAR+ + +D Y + K P+KWTAPE
Sbjct: 345 LESRNYIHRDLAARNVLVGEHNIYKVADFGLARVFKVDNEDIYESRHEIKLPVKWTAPEA 404
Query: 420 LAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHML 461
+ N FS KSDVW+FGILL+EI TYG PY G+ A V ML
Sbjct: 405 IRSNKFSIKSDVWSFGILLYEIITYGKMPYSGMTGAQVIQML 446
>AL121963-8|CAB87592.2| 505|Homo sapiens fyn-related kinase
protein.
Length = 505
Score = 336 bits (827), Expect = 7e-92
Identities = 184/402 (45%), Positives = 239/402 (59%), Gaps = 16/402 (3%)
Query: 74 FVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAH-------TLTGAVGWVPSNYVT 126
FVAL+D+QA L+ + G++++++ G W H + G++PSNYV
Sbjct: 47 FVALFDYQARTAEDLSFRAGDKLQVLDTLHEGWWFARHLEKRRDGSSQQLQGYIPSNYVA 106
Query: 127 PVNSLEKHSWYHGPISRNAAE--YLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYR 184
SL+ W+ G I R+ AE L S GSFL+RESES G+ S+S+ V HYR
Sbjct: 107 EDRSLQAEPWFFGAIGRSDAEKQLLYSENKTGSFLIRESESQKGEFSLSVLDGAVVKHYR 166
Query: 185 INEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKPTVFPLA--PPDH 242
I +G ++T F TL E V H++ DGL +L P K P F L+ D
Sbjct: 167 IKRLDEGGFFLTRRRIFSTLNEFVSHYTKTSDGLCVKLGKPCLKIQVPAPFDLSYKTVDQ 226
Query: 243 WEIDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASIMKEMR 302
WEIDR I + +LG GQ+G+V+E W VAVKTLK +M DFL EA IMK +R
Sbjct: 227 WEIDRNSIQLLKRLGSGQFGEVWEGLWNN-TTPVAVKTLKPGSMDPNDFLREAQIMKNLR 285
Query: 303 HPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIASGMSY 362
HP L+QL VCT E P YIITE M G+L EYL+ + + MA Q+ASGM+Y
Sbjct: 286 HPKLIQLYAVCTLEDPIYIITELMRHGSLQEYLQNDTGSKI-HLTQQVDMAAQVASGMAY 344
Query: 363 LESRSFIHRDLAARNCLVGENHLVKVADFGLARLMR---DDTYTAHAGAKFPIKWTAPEG 419
LESR++IHRDLAARN LVGE+++ KVADFGLAR+ + +D Y + K P+KWTAPE
Sbjct: 345 LESRNYIHRDLAARNVLVGEHNIYKVADFGLARVFKVDNEDIYESRHEIKLPVKWTAPEA 404
Query: 420 LAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHML 461
+ N FS KSDVW+FGILL+EI TYG PY G+ A V ML
Sbjct: 405 IRSNKFSIKSDVWSFGILLYEIITYGKMPYSGMTGAQVIQML 446
>AL353092-1|CAI19695.1| 504|Homo sapiens hemopoietic cell kinase
protein.
Length = 504
Score = 332 bits (815), Expect = 2e-90
Identities = 183/407 (44%), Positives = 268/407 (65%), Gaps = 20/407 (4%)
Query: 67 EEDDPQLFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTL-TGAVGWVPSNYV 125
E + + VALYD++A L+ +KG+Q+ ++ +SGEW +A +L T G++PSNYV
Sbjct: 54 EGSEDIIVVALYDYEAIHHEDLSFQKGDQMVVLE--ESGEWWKARSLATRKEGYIPSNYV 111
Query: 126 TPVNSLEKHSWYHGPISRNAAE-YLLSSG-INGSFLVRESESSPGQRSISLR-YEGR--- 179
V+SLE W+ ISR AE LL+ G + GSF++R+SE++ G S+S+R Y+ R
Sbjct: 112 ARVDSLETEEWFFKGISRKDAERQLLAPGNMLGSFMIRDSETTKGSYSLSVRDYDPRQGD 171
Query: 180 -VYHYRINEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKPTVFPLA 238
V HY+I +G Y++ S F TL ELV H+ DGL +L P SKP P
Sbjct: 172 TVKHYKIRTLDNGGFYISPRSTFSTLQELVDHYKKGNDGLCQKLSVPCMS-SKPQK-PWE 229
Query: 239 PPDHWEIDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASIM 298
D WEI R + ++ KLG GQ+G+V+ A + + + VAVKT+K +M+++ FL EA++M
Sbjct: 230 K-DAWEIPRESLKLEKKLGAGQFGEVWMATYNK-HTKVAVKTMKPGSMSVEAFLAEANVM 287
Query: 299 KEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRA--GARECVPGAVVLMYMATQI 356
K ++H LV+L V T+EP YIITEFM++G+LL++L++ G+++ +P L+ + QI
Sbjct: 288 KTLQHDKLVKLHAVVTKEP-IYIITEFMAKGSLLDFLKSDEGSKQPLPK---LIDFSAQI 343
Query: 357 ASGMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWTA 416
A GM+++E R++IHRDL A N LV + + K+ADFGLAR++ D+ YTA GAKFPIKWTA
Sbjct: 344 AEGMAFIEQRNYIHRDLRAANILVSASLVCKIADFGLARVIEDNEYTAREGAKFPIKWTA 403
Query: 417 PEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
PE + + +F+ KSDVW+FGILL EI TYG PYPG+ +V LE+
Sbjct: 404 PEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPEVIRALER 450
>AL049539-2|CAI22967.1| 504|Homo sapiens hemopoietic cell kinase
protein.
Length = 504
Score = 332 bits (815), Expect = 2e-90
Identities = 183/407 (44%), Positives = 268/407 (65%), Gaps = 20/407 (4%)
Query: 67 EEDDPQLFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTL-TGAVGWVPSNYV 125
E + + VALYD++A L+ +KG+Q+ ++ +SGEW +A +L T G++PSNYV
Sbjct: 54 EGSEDIIVVALYDYEAIHHEDLSFQKGDQMVVLE--ESGEWWKARSLATRKEGYIPSNYV 111
Query: 126 TPVNSLEKHSWYHGPISRNAAE-YLLSSG-INGSFLVRESESSPGQRSISLR-YEGR--- 179
V+SLE W+ ISR AE LL+ G + GSF++R+SE++ G S+S+R Y+ R
Sbjct: 112 ARVDSLETEEWFFKGISRKDAERQLLAPGNMLGSFMIRDSETTKGSYSLSVRDYDPRQGD 171
Query: 180 -VYHYRINEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKPTVFPLA 238
V HY+I +G Y++ S F TL ELV H+ DGL +L P SKP P
Sbjct: 172 TVKHYKIRTLDNGGFYISPRSTFSTLQELVDHYKKGNDGLCQKLSVPCMS-SKPQK-PWE 229
Query: 239 PPDHWEIDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASIM 298
D WEI R + ++ KLG GQ+G+V+ A + + + VAVKT+K +M+++ FL EA++M
Sbjct: 230 K-DAWEIPRESLKLEKKLGAGQFGEVWMATYNK-HTKVAVKTMKPGSMSVEAFLAEANVM 287
Query: 299 KEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRA--GARECVPGAVVLMYMATQI 356
K ++H LV+L V T+EP YIITEFM++G+LL++L++ G+++ +P L+ + QI
Sbjct: 288 KTLQHDKLVKLHAVVTKEP-IYIITEFMAKGSLLDFLKSDEGSKQPLPK---LIDFSAQI 343
Query: 357 ASGMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWTA 416
A GM+++E R++IHRDL A N LV + + K+ADFGLAR++ D+ YTA GAKFPIKWTA
Sbjct: 344 AEGMAFIEQRNYIHRDLRAANILVSASLVCKIADFGLARVIEDNEYTAREGAKFPIKWTA 403
Query: 417 PEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
PE + + +F+ KSDVW+FGILL EI TYG PYPG+ +V LE+
Sbjct: 404 PEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPEVIRALER 450
>M16592-1|AAA52644.1| 505|Homo sapiens HCK protein.
Length = 505
Score = 331 bits (814), Expect = 3e-90
Identities = 182/401 (45%), Positives = 266/401 (66%), Gaps = 20/401 (4%)
Query: 73 LFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTL-TGAVGWVPSNYVTPVNSL 131
+ VALYD++A L+ +KG+Q+ ++ +SGEW +A +L T G++PSNYV V+SL
Sbjct: 61 IVVALYDYEAIHHEDLSFQKGDQMVVLE--ESGEWWKARSLATRKEGYIPSNYVARVDSL 118
Query: 132 EKHSWYHGPISRNAAE-YLLSSG-INGSFLVRESESSPGQRSISLR-YEGR----VYHYR 184
E W+ ISR AE LL+ G + GSF++R+SE++ G S+S+R Y+ R V HY+
Sbjct: 119 ETEEWFFKGISRKDAERQLLAPGNMLGSFMIRDSETTKGSYSLSVRDYDPRQGDTVKHYK 178
Query: 185 INEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKPTVFPLAPPDHWE 244
I +G Y++ S F TL ELV H+ DGL +L P SKP P D WE
Sbjct: 179 IRTLDNGGFYISPRSTFSTLQELVDHYKKGNDGLCQKLSVPCMS-SKPQK-PWEK-DAWE 235
Query: 245 IDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASIMKEMRHP 304
I R + ++ KLG GQ+G+V+ A + + + VAVKT+K +M+++ FL EA++MK ++H
Sbjct: 236 IPRESLKLEKKLGAGQFGEVWMATYNK-HTKVAVKTMKPGSMSVEAFLAEANVMKTLQHD 294
Query: 305 NLVQLLGVCTREPPFYIITEFMSRGNLLEYLRA--GARECVPGAVVLMYMATQIASGMSY 362
LV+L V T+EP YIITEFM++G+LL++L++ G+++ +P L+ + QIA GM++
Sbjct: 295 KLVKLHAVVTKEP-IYIITEFMAKGSLLDFLKSDEGSKQPLPK---LIDFSAQIAEGMAF 350
Query: 363 LESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEGLAY 422
+E R++IHRDL A N LV + + K+ADFGLAR++ D+ YTA GAKFPIKWTAPE + +
Sbjct: 351 IEQRNYIHRDLRAANILVSASLVCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINF 410
Query: 423 NTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
+F+ KSDVW+FGILL EI TYG PYPG+ +V LE+
Sbjct: 411 GSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPEVIRALER 451
>M16591-1|AAA52643.1| 505|Homo sapiens HCK protein.
Length = 505
Score = 331 bits (814), Expect = 3e-90
Identities = 182/401 (45%), Positives = 266/401 (66%), Gaps = 20/401 (4%)
Query: 73 LFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTL-TGAVGWVPSNYVTPVNSL 131
+ VALYD++A L+ +KG+Q+ ++ +SGEW +A +L T G++PSNYV V+SL
Sbjct: 61 IVVALYDYEAIHHEDLSFQKGDQMVVLE--ESGEWWKARSLATRKEGYIPSNYVARVDSL 118
Query: 132 EKHSWYHGPISRNAAE-YLLSSG-INGSFLVRESESSPGQRSISLR-YEGR----VYHYR 184
E W+ ISR AE LL+ G + GSF++R+SE++ G S+S+R Y+ R V HY+
Sbjct: 119 ETEEWFFKGISRKDAERQLLAPGNMLGSFMIRDSETTKGSYSLSVRDYDPRQGDTVKHYK 178
Query: 185 INEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKPTVFPLAPPDHWE 244
I +G Y++ S F TL ELV H+ DGL +L P SKP P D WE
Sbjct: 179 IRTLDNGGFYISPRSTFSTLQELVDHYKKGNDGLCQKLSVPCMS-SKPQK-PWEK-DAWE 235
Query: 245 IDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASIMKEMRHP 304
I R + ++ KLG GQ+G+V+ A + + + VAVKT+K +M+++ FL EA++MK ++H
Sbjct: 236 IPRESLKLEKKLGAGQFGEVWMATYNK-HTKVAVKTMKPGSMSVEAFLAEANVMKTLQHD 294
Query: 305 NLVQLLGVCTREPPFYIITEFMSRGNLLEYLRA--GARECVPGAVVLMYMATQIASGMSY 362
LV+L V T+EP YIITEFM++G+LL++L++ G+++ +P L+ + QIA GM++
Sbjct: 295 KLVKLHAVVTKEP-IYIITEFMAKGSLLDFLKSDEGSKQPLPK---LIDFSAQIAEGMAF 350
Query: 363 LESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEGLAY 422
+E R++IHRDL A N LV + + K+ADFGLAR++ D+ YTA GAKFPIKWTAPE + +
Sbjct: 351 IEQRNYIHRDLRAANILVSASLVCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINF 410
Query: 423 NTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
+F+ KSDVW+FGILL EI TYG PYPG+ +V LE+
Sbjct: 411 GSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPEVIRALER 451
>BC114463-1|AAI14464.2| 526|Homo sapiens hemopoietic cell kinase
protein.
Length = 526
Score = 331 bits (814), Expect = 3e-90
Identities = 182/401 (45%), Positives = 266/401 (66%), Gaps = 20/401 (4%)
Query: 73 LFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTL-TGAVGWVPSNYVTPVNSL 131
+ VALYD++A L+ +KG+Q+ ++ +SGEW +A +L T G++PSNYV V+SL
Sbjct: 82 IVVALYDYEAIHHEDLSFQKGDQMVVLE--ESGEWWKARSLATRKEGYIPSNYVARVDSL 139
Query: 132 EKHSWYHGPISRNAAE-YLLSSG-INGSFLVRESESSPGQRSISLR-YEGR----VYHYR 184
E W+ ISR AE LL+ G + GSF++R+SE++ G S+S+R Y+ R V HY+
Sbjct: 140 ETEEWFFKGISRKDAERQLLAPGNMLGSFMIRDSETTKGSYSLSVRDYDPRQGDTVKHYK 199
Query: 185 INEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKPTVFPLAPPDHWE 244
I +G Y++ S F TL ELV H+ DGL +L P SKP P D WE
Sbjct: 200 IRTLDNGGFYISPRSTFSTLQELVDHYKKGNDGLCQKLSVPCMS-SKPQK-PWEK-DAWE 256
Query: 245 IDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASIMKEMRHP 304
I R + ++ KLG GQ+G+V+ A + + + VAVKT+K +M+++ FL EA++MK ++H
Sbjct: 257 IPRESLKLEKKLGAGQFGEVWMATYNK-HTKVAVKTMKPGSMSVEAFLAEANVMKTLQHD 315
Query: 305 NLVQLLGVCTREPPFYIITEFMSRGNLLEYLRA--GARECVPGAVVLMYMATQIASGMSY 362
LV+L V T+EP YIITEFM++G+LL++L++ G+++ +P L+ + QIA GM++
Sbjct: 316 KLVKLHAVVTKEP-IYIITEFMAKGSLLDFLKSDEGSKQPLPK---LIDFSAQIAEGMAF 371
Query: 363 LESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEGLAY 422
+E R++IHRDL A N LV + + K+ADFGLAR++ D+ YTA GAKFPIKWTAPE + +
Sbjct: 372 IEQRNYIHRDLRAANILVSASLVCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINF 431
Query: 423 NTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
+F+ KSDVW+FGILL EI TYG PYPG+ +V LE+
Sbjct: 432 GSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPEVIRALER 472
>BC108931-1|AAI08932.2| 526|Homo sapiens hemopoietic cell kinase
protein.
Length = 526
Score = 331 bits (814), Expect = 3e-90
Identities = 182/401 (45%), Positives = 266/401 (66%), Gaps = 20/401 (4%)
Query: 73 LFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTL-TGAVGWVPSNYVTPVNSL 131
+ VALYD++A L+ +KG+Q+ ++ +SGEW +A +L T G++PSNYV V+SL
Sbjct: 82 IVVALYDYEAIHHEDLSFQKGDQMVVLE--ESGEWWKARSLATRKEGYIPSNYVARVDSL 139
Query: 132 EKHSWYHGPISRNAAE-YLLSSG-INGSFLVRESESSPGQRSISLR-YEGR----VYHYR 184
E W+ ISR AE LL+ G + GSF++R+SE++ G S+S+R Y+ R V HY+
Sbjct: 140 ETEEWFFKGISRKDAERQLLAPGNMLGSFMIRDSETTKGSYSLSVRDYDPRQGDTVKHYK 199
Query: 185 INEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKPTVFPLAPPDHWE 244
I +G Y++ S F TL ELV H+ DGL +L P SKP P D WE
Sbjct: 200 IRTLDNGGFYISPRSTFSTLQELVDHYKKGNDGLCQKLSVPCMS-SKPQK-PWEK-DAWE 256
Query: 245 IDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASIMKEMRHP 304
I R + ++ KLG GQ+G+V+ A + + + VAVKT+K +M+++ FL EA++MK ++H
Sbjct: 257 IPRESLKLEKKLGAGQFGEVWMATYNK-HTKVAVKTMKPGSMSVEAFLAEANVMKTLQHD 315
Query: 305 NLVQLLGVCTREPPFYIITEFMSRGNLLEYLRA--GARECVPGAVVLMYMATQIASGMSY 362
LV+L V T+EP YIITEFM++G+LL++L++ G+++ +P L+ + QIA GM++
Sbjct: 316 KLVKLHAVVTKEP-IYIITEFMAKGSLLDFLKSDEGSKQPLPK---LIDFSAQIAEGMAF 371
Query: 363 LESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEGLAY 422
+E R++IHRDL A N LV + + K+ADFGLAR++ D+ YTA GAKFPIKWTAPE + +
Sbjct: 372 IEQRNYIHRDLRAANILVSASLVCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINF 431
Query: 423 NTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
+F+ KSDVW+FGILL EI TYG PYPG+ +V LE+
Sbjct: 432 GSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPEVIRALER 472
>BC108930-1|AAI08931.2| 526|Homo sapiens hemopoietic cell kinase
protein.
Length = 526
Score = 331 bits (814), Expect = 3e-90
Identities = 182/401 (45%), Positives = 266/401 (66%), Gaps = 20/401 (4%)
Query: 73 LFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTL-TGAVGWVPSNYVTPVNSL 131
+ VALYD++A L+ +KG+Q+ ++ +SGEW +A +L T G++PSNYV V+SL
Sbjct: 82 IVVALYDYEAIHHEDLSFQKGDQMVVLE--ESGEWWKARSLATRKEGYIPSNYVARVDSL 139
Query: 132 EKHSWYHGPISRNAAE-YLLSSG-INGSFLVRESESSPGQRSISLR-YEGR----VYHYR 184
E W+ ISR AE LL+ G + GSF++R+SE++ G S+S+R Y+ R V HY+
Sbjct: 140 ETEEWFFKGISRKDAERQLLAPGNMLGSFMIRDSETTKGSYSLSVRDYDPRQGDTVKHYK 199
Query: 185 INEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKPTVFPLAPPDHWE 244
I +G Y++ S F TL ELV H+ DGL +L P SKP P D WE
Sbjct: 200 IRTLDNGGFYISPRSTFSTLQELVDHYKKGNDGLCQKLSVPCMS-SKPQK-PWEK-DAWE 256
Query: 245 IDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASIMKEMRHP 304
I R + ++ KLG GQ+G+V+ A + + + VAVKT+K +M+++ FL EA++MK ++H
Sbjct: 257 IPRESLKLEKKLGAGQFGEVWMATYNK-HTKVAVKTMKPGSMSVEAFLAEANVMKTLQHD 315
Query: 305 NLVQLLGVCTREPPFYIITEFMSRGNLLEYLRA--GARECVPGAVVLMYMATQIASGMSY 362
LV+L V T+EP YIITEFM++G+LL++L++ G+++ +P L+ + QIA GM++
Sbjct: 316 KLVKLHAVVTKEP-IYIITEFMAKGSLLDFLKSDEGSKQPLPK---LIDFSAQIAEGMAF 371
Query: 363 LESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEGLAY 422
+E R++IHRDL A N LV + + K+ADFGLAR++ D+ YTA GAKFPIKWTAPE + +
Sbjct: 372 IEQRNYIHRDLRAANILVSASLVCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINF 431
Query: 423 NTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
+F+ KSDVW+FGILL EI TYG PYPG+ +V LE+
Sbjct: 432 GSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPEVIRALER 472
>BC094847-1|AAH94847.2| 526|Homo sapiens hemopoietic cell kinase
protein.
Length = 526
Score = 331 bits (814), Expect = 3e-90
Identities = 182/401 (45%), Positives = 266/401 (66%), Gaps = 20/401 (4%)
Query: 73 LFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTL-TGAVGWVPSNYVTPVNSL 131
+ VALYD++A L+ +KG+Q+ ++ +SGEW +A +L T G++PSNYV V+SL
Sbjct: 82 IVVALYDYEAIHHEDLSFQKGDQMVVLE--ESGEWWKARSLATRKEGYIPSNYVARVDSL 139
Query: 132 EKHSWYHGPISRNAAE-YLLSSG-INGSFLVRESESSPGQRSISLR-YEGR----VYHYR 184
E W+ ISR AE LL+ G + GSF++R+SE++ G S+S+R Y+ R V HY+
Sbjct: 140 ETEEWFFKGISRKDAERQLLAPGNMLGSFMIRDSETTKGSYSLSVRDYDPRQGDTVKHYK 199
Query: 185 INEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKPTVFPLAPPDHWE 244
I +G Y++ S F TL ELV H+ DGL +L P SKP P D WE
Sbjct: 200 IRTLDNGGFYISPRSTFSTLQELVDHYKKGNDGLCQKLSVPCMS-SKPQK-PWEK-DAWE 256
Query: 245 IDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASIMKEMRHP 304
I R + ++ KLG GQ+G+V+ A + + + VAVKT+K +M+++ FL EA++MK ++H
Sbjct: 257 IPRESLKLEKKLGAGQFGEVWMATYNK-HTKVAVKTMKPGSMSVEAFLAEANVMKTLQHD 315
Query: 305 NLVQLLGVCTREPPFYIITEFMSRGNLLEYLRA--GARECVPGAVVLMYMATQIASGMSY 362
LV+L V T+EP YIITEFM++G+LL++L++ G+++ +P L+ + QIA GM++
Sbjct: 316 KLVKLHAVVTKEP-IYIITEFMAKGSLLDFLKSDEGSKQPLPK---LIDFSAQIAEGMAF 371
Query: 363 LESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEGLAY 422
+E R++IHRDL A N LV + + K+ADFGLAR++ D+ YTA GAKFPIKWTAPE + +
Sbjct: 372 IEQRNYIHRDLRAANILVSASLVCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINF 431
Query: 423 NTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
+F+ KSDVW+FGILL EI TYG PYPG+ +V LE+
Sbjct: 432 GSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPEVIRALER 472
>BC014435-1|AAH14435.2| 526|Homo sapiens hemopoietic cell kinase
protein.
Length = 526
Score = 331 bits (814), Expect = 3e-90
Identities = 182/401 (45%), Positives = 266/401 (66%), Gaps = 20/401 (4%)
Query: 73 LFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTL-TGAVGWVPSNYVTPVNSL 131
+ VALYD++A L+ +KG+Q+ ++ +SGEW +A +L T G++PSNYV V+SL
Sbjct: 82 IVVALYDYEAIHHEDLSFQKGDQMVVLE--ESGEWWKARSLATRKEGYIPSNYVARVDSL 139
Query: 132 EKHSWYHGPISRNAAE-YLLSSG-INGSFLVRESESSPGQRSISLR-YEGR----VYHYR 184
E W+ ISR AE LL+ G + GSF++R+SE++ G S+S+R Y+ R V HY+
Sbjct: 140 ETEEWFFKGISRKDAERQLLAPGNMLGSFMIRDSETTKGSYSLSVRDYDPRQGDTVKHYK 199
Query: 185 INEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKPTVFPLAPPDHWE 244
I +G Y++ S F TL ELV H+ DGL +L P SKP P D WE
Sbjct: 200 IRTLDNGGFYISPRSTFSTLQELVDHYKKGNDGLCQKLSVPCMS-SKPQK-PWEK-DAWE 256
Query: 245 IDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASIMKEMRHP 304
I R + ++ KLG GQ+G+V+ A + + + VAVKT+K +M+++ FL EA++MK ++H
Sbjct: 257 IPRESLKLEKKLGAGQFGEVWMATYNK-HTKVAVKTMKPGSMSVEAFLAEANVMKTLQHD 315
Query: 305 NLVQLLGVCTREPPFYIITEFMSRGNLLEYLRA--GARECVPGAVVLMYMATQIASGMSY 362
LV+L V T+EP YIITEFM++G+LL++L++ G+++ +P L+ + QIA GM++
Sbjct: 316 KLVKLHAVVTKEP-IYIITEFMAKGSLLDFLKSDEGSKQPLPK---LIDFSAQIAEGMAF 371
Query: 363 LESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEGLAY 422
+E R++IHRDL A N LV + + K+ADFGLAR++ D+ YTA GAKFPIKWTAPE + +
Sbjct: 372 IEQRNYIHRDLRAANILVSASLVCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINF 431
Query: 423 NTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
+F+ KSDVW+FGILL EI TYG PYPG+ +V LE+
Sbjct: 432 GSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPEVIRALER 472
>AL353092-2|CAI19694.1| 505|Homo sapiens hemopoietic cell kinase
protein.
Length = 505
Score = 331 bits (814), Expect = 3e-90
Identities = 182/401 (45%), Positives = 266/401 (66%), Gaps = 20/401 (4%)
Query: 73 LFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTL-TGAVGWVPSNYVTPVNSL 131
+ VALYD++A L+ +KG+Q+ ++ +SGEW +A +L T G++PSNYV V+SL
Sbjct: 61 IVVALYDYEAIHHEDLSFQKGDQMVVLE--ESGEWWKARSLATRKEGYIPSNYVARVDSL 118
Query: 132 EKHSWYHGPISRNAAE-YLLSSG-INGSFLVRESESSPGQRSISLR-YEGR----VYHYR 184
E W+ ISR AE LL+ G + GSF++R+SE++ G S+S+R Y+ R V HY+
Sbjct: 119 ETEEWFFKGISRKDAERQLLAPGNMLGSFMIRDSETTKGSYSLSVRDYDPRQGDTVKHYK 178
Query: 185 INEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKPTVFPLAPPDHWE 244
I +G Y++ S F TL ELV H+ DGL +L P SKP P D WE
Sbjct: 179 IRTLDNGGFYISPRSTFSTLQELVDHYKKGNDGLCQKLSVPCMS-SKPQK-PWEK-DAWE 235
Query: 245 IDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASIMKEMRHP 304
I R + ++ KLG GQ+G+V+ A + + + VAVKT+K +M+++ FL EA++MK ++H
Sbjct: 236 IPRESLKLEKKLGAGQFGEVWMATYNK-HTKVAVKTMKPGSMSVEAFLAEANVMKTLQHD 294
Query: 305 NLVQLLGVCTREPPFYIITEFMSRGNLLEYLRA--GARECVPGAVVLMYMATQIASGMSY 362
LV+L V T+EP YIITEFM++G+LL++L++ G+++ +P L+ + QIA GM++
Sbjct: 295 KLVKLHAVVTKEP-IYIITEFMAKGSLLDFLKSDEGSKQPLPK---LIDFSAQIAEGMAF 350
Query: 363 LESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEGLAY 422
+E R++IHRDL A N LV + + K+ADFGLAR++ D+ YTA GAKFPIKWTAPE + +
Sbjct: 351 IEQRNYIHRDLRAANILVSASLVCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINF 410
Query: 423 NTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
+F+ KSDVW+FGILL EI TYG PYPG+ +V LE+
Sbjct: 411 GSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPEVIRALER 451
>AL049539-1|CAI22966.1| 505|Homo sapiens hemopoietic cell kinase
protein.
Length = 505
Score = 331 bits (814), Expect = 3e-90
Identities = 182/401 (45%), Positives = 266/401 (66%), Gaps = 20/401 (4%)
Query: 73 LFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTL-TGAVGWVPSNYVTPVNSL 131
+ VALYD++A L+ +KG+Q+ ++ +SGEW +A +L T G++PSNYV V+SL
Sbjct: 61 IVVALYDYEAIHHEDLSFQKGDQMVVLE--ESGEWWKARSLATRKEGYIPSNYVARVDSL 118
Query: 132 EKHSWYHGPISRNAAE-YLLSSG-INGSFLVRESESSPGQRSISLR-YEGR----VYHYR 184
E W+ ISR AE LL+ G + GSF++R+SE++ G S+S+R Y+ R V HY+
Sbjct: 119 ETEEWFFKGISRKDAERQLLAPGNMLGSFMIRDSETTKGSYSLSVRDYDPRQGDTVKHYK 178
Query: 185 INEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKPTVFPLAPPDHWE 244
I +G Y++ S F TL ELV H+ DGL +L P SKP P D WE
Sbjct: 179 IRTLDNGGFYISPRSTFSTLQELVDHYKKGNDGLCQKLSVPCMS-SKPQK-PWEK-DAWE 235
Query: 245 IDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASIMKEMRHP 304
I R + ++ KLG GQ+G+V+ A + + + VAVKT+K +M+++ FL EA++MK ++H
Sbjct: 236 IPRESLKLEKKLGAGQFGEVWMATYNK-HTKVAVKTMKPGSMSVEAFLAEANVMKTLQHD 294
Query: 305 NLVQLLGVCTREPPFYIITEFMSRGNLLEYLRA--GARECVPGAVVLMYMATQIASGMSY 362
LV+L V T+EP YIITEFM++G+LL++L++ G+++ +P L+ + QIA GM++
Sbjct: 295 KLVKLHAVVTKEP-IYIITEFMAKGSLLDFLKSDEGSKQPLPK---LIDFSAQIAEGMAF 350
Query: 363 LESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEGLAY 422
+E R++IHRDL A N LV + + K+ADFGLAR++ D+ YTA GAKFPIKWTAPE + +
Sbjct: 351 IEQRNYIHRDLRAANILVSASLVCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINF 410
Query: 423 NTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
+F+ KSDVW+FGILL EI TYG PYPG+ +V LE+
Sbjct: 411 GSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPEVIRALER 451
>AM491362-1|CAM33012.1| 585|Homo sapiens bcr-abl1 e6a2 chimeric
protein protein.
Length = 585
Score = 330 bits (812), Expect = 5e-90
Identities = 151/203 (74%), Positives = 173/203 (85%), Gaps = 2/203 (0%)
Query: 53 ANRWTSKENLLAHHEEDDPQLFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHT 112
A RW SKE+LLA E+DP LFVALYDF A G+N L++ KGE++R++ YN +GEWCEA T
Sbjct: 384 AARWNSKEDLLAGPSENDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQT 443
Query: 113 LTGAVGWVPSNYVTPVNSLEKHSWYHGPISRNAAEYLLSSGINGSFLVRESESSPGQRSI 172
G GWVPSNY+TPVNSLEKHSWYHGP+SRNAAEYLLSSGINGSFLVRESESSPGQRSI
Sbjct: 444 KNGQ-GWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSI 502
Query: 173 SLRYEGRVYHYRINEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKP 232
SLRYEGRVYHYRIN +DGK+YV+SES+F TLAELVHHHS DGLIT L YPAPKR+KP
Sbjct: 503 SLRYEGRVYHYRINTASDGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRNKP 562
Query: 233 TVFPLAPP-DHWEIDRTDIVMKH 254
TV+ ++P D WE++RTDI MKH
Sbjct: 563 TVYGVSPNYDKWEMERTDITMKH 585
>BC113854-1|AAI13855.2| 504|Homo sapiens HCK protein protein.
Length = 504
Score = 330 bits (810), Expect = 8e-90
Identities = 182/407 (44%), Positives = 267/407 (65%), Gaps = 20/407 (4%)
Query: 67 EEDDPQLFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTL-TGAVGWVPSNYV 125
E + + VALYD++A L+ +KG+Q+ ++ +SGEW +A +L T G++PSNYV
Sbjct: 54 EGSEDIIVVALYDYEAIHHEDLSFQKGDQMVVLE--ESGEWWKARSLATRKEGYIPSNYV 111
Query: 126 TPVNSLEKHSWYHGPISRNAAE-YLLSSG-INGSFLVRESESSPGQRSISLR-YEGR--- 179
V+SLE W+ ISR AE LL+ G + GSF++R+SE++ G S+S+R Y+ R
Sbjct: 112 ARVDSLETEEWFFKGISRKDAERQLLAPGNMLGSFMIRDSETTKGSYSLSVRDYDPRQGD 171
Query: 180 -VYHYRINEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKPTVFPLA 238
V HY+I +G Y++ S F TL ELV H+ DGL +L P SKP P
Sbjct: 172 TVKHYKIRTLDNGGFYISPRSTFSTLQELVDHYKKGNDGLCQKLSVPCMS-SKPQK-PWE 229
Query: 239 PPDHWEIDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASIM 298
D WEI R + ++ KLG GQ+G+V+ A + + + VAVKT+K +M+++ FL EA++M
Sbjct: 230 K-DAWEIPRESLKLEKKLGAGQFGEVWMATYNK-HTKVAVKTMKPGSMSVEAFLAEANVM 287
Query: 299 KEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRA--GARECVPGAVVLMYMATQI 356
K ++H LV+L V T+EP YIITEFM++G+LL++L++ G+++ +P L+ + QI
Sbjct: 288 KTLQHDKLVKLHAVVTKEP-IYIITEFMAKGSLLDFLKSDEGSKQPLPK---LIDFSAQI 343
Query: 357 ASGMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWTA 416
A GM+++E R++ HRDL A N LV + + K+ADFGLAR++ D+ YTA GAKFPIKWTA
Sbjct: 344 AEGMAFIEQRNYTHRDLRAANILVSASLVCKIADFGLARVIEDNEYTAREGAKFPIKWTA 403
Query: 417 PEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
PE + + +F+ KSDVW+FGILL EI TYG PYPG+ +V LE+
Sbjct: 404 PEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPEVIRALER 450
>AM491363-1|CAM33013.1| 498|Homo sapiens bcr-abl1 e19a2 chimeric
protein protein.
Length = 498
Score = 329 bits (808), Expect = 1e-89
Identities = 150/203 (73%), Positives = 173/203 (85%), Gaps = 2/203 (0%)
Query: 53 ANRWTSKENLLAHHEEDDPQLFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHT 112
A RW SKENLLA E+DP LFVALYDF A G+N L++ KGE++R++ YN +GEWCEA T
Sbjct: 297 AARWNSKENLLAGPSENDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQT 356
Query: 113 LTGAVGWVPSNYVTPVNSLEKHSWYHGPISRNAAEYLLSSGINGSFLVRESESSPGQRSI 172
G GWVPSNY+TPVNSLEKHSWYHGP+SRNAAE+LLSSGINGSFLVRESESSPGQRSI
Sbjct: 357 KNGQ-GWVPSNYITPVNSLEKHSWYHGPVSRNAAEHLLSSGINGSFLVRESESSPGQRSI 415
Query: 173 SLRYEGRVYHYRINEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKP 232
SLRYEGRVYHYRIN +DGK+YV+SES+F TLAELVHHHS DGLIT L YPAPKR+KP
Sbjct: 416 SLRYEGRVYHYRINTASDGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRNKP 475
Query: 233 TVFPLAPP-DHWEIDRTDIVMKH 254
+V+ ++P D WE++RTDI MKH
Sbjct: 476 SVYGVSPNYDKWEMERTDITMKH 498
>AK026432-1|BAB15482.1| 505|Homo sapiens protein ( Homo sapiens
cDNA: FLJ22779 fis, clone KAIA1741. ).
Length = 505
Score = 326 bits (800), Expect = 1e-88
Identities = 181/401 (45%), Positives = 265/401 (66%), Gaps = 20/401 (4%)
Query: 73 LFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTL-TGAVGWVPSNYVTPVNSL 131
+ VALYD++A L+ +KG+Q+ ++ +SGEW +A +L T G++PSNYV V+SL
Sbjct: 61 IVVALYDYEAIHHEDLSFQKGDQMVVLE--ESGEWWKARSLATRKEGYIPSNYVARVDSL 118
Query: 132 EKHSWYHGPISRNAAE-YLLSSG-INGSFLVRESESSPGQRSISLR-YEGR----VYHYR 184
E + ISR AE LL+ G + GSF++R+SE++ G S+S+R Y+ R V HY+
Sbjct: 119 ETEERFFKGISRKDAERQLLAPGNMLGSFMIRDSETTKGSYSLSVRDYDPRQGDTVKHYK 178
Query: 185 INEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKPTVFPLAPPDHWE 244
I +G Y++ S F TL ELV H+ DGL +L P SKP P D WE
Sbjct: 179 IRTLDNGGFYISPRSTFSTLQELVDHYKKGNDGLCQKLSVPCMS-SKPQK-PWEK-DAWE 235
Query: 245 IDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASIMKEMRHP 304
I R + ++ KLG GQ+G+V+ A + + + VAVKT+K +M+++ FL EA++MK ++H
Sbjct: 236 IPRESLKLEKKLGAGQFGEVWMATYNK-HTKVAVKTMKPGSMSVEAFLAEANVMKTLQHD 294
Query: 305 NLVQLLGVCTREPPFYIITEFMSRGNLLEYLRA--GARECVPGAVVLMYMATQIASGMSY 362
LV+L V T+EP YIITEFM++G+LL++L++ G+++ +P L+ + QIA GM++
Sbjct: 295 KLVKLHAVVTKEP-IYIITEFMAKGSLLDFLKSDEGSKQPLPK---LIDFSAQIAEGMAF 350
Query: 363 LESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEGLAY 422
+E R++IHRDL A N LV + + K+ADFGLAR++ D+ YTA GAKFPIKWTAPE + +
Sbjct: 351 IEQRNYIHRDLRAANILVSASLVCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINF 410
Query: 423 NTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
+F+ KSDVW+FGILL EI TYG PYPG+ +V LE+
Sbjct: 411 GSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPEVIRALER 451
>U07236-1|AAA18225.1| 512|Homo sapiens lymphocyte-specific protein
tyrosine kinase protein.
Length = 512
Score = 321 bits (789), Expect = 3e-87
Identities = 181/403 (44%), Positives = 256/403 (63%), Gaps = 21/403 (5%)
Query: 73 LFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTLT-GAVGWVPSNYVTPVNSL 131
L +AL+ ++ + L +KGEQ+RI+ +SGEW +A +LT G G++P N+V NSL
Sbjct: 65 LVIALHSYEPSHDGDLGFEKGEQLRILE--QSGEWWKAQSLTTGQEGFIPFNFVAKANSL 122
Query: 132 EKHSWYHGPISRNAAE-YLLSSG-INGSFLVRESESSPGQRSISLR----YEGRVY-HYR 184
E W+ +SR AE LL+ G +GSFL+RESES+ G S+S+R +G V HY+
Sbjct: 123 EPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQNQGEVVKHYK 182
Query: 185 INEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKPTVFPLAP--PDH 242
I +G Y++ F L ELV H++ A DGL T+L P + KP P P D
Sbjct: 183 IRNLDNGGFYISPRITFPGLHELVRHYTNASDGLCTRLSRPC-QTQKPQK-PQKPWWEDE 240
Query: 243 WEIDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASIMKEMR 302
WE+ R + + +LG GQ+G+V+ + G+ VAVK+LK +M+ FL EA++MK+++
Sbjct: 241 WEVPRETLKLVERLGAGQFGEVW-MGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQ 299
Query: 303 HPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLR--AGARECVPGAVVLMYMATQIASGM 360
H LV+L V T+EP YIITE+M G+L+++L+ +G + + L+ MA QIA GM
Sbjct: 300 HQRLVRLYAVVTQEP-IYIITEYMENGSLVDFLKTPSGIKLTINK---LLDMAAQIAEGM 355
Query: 361 SYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEGL 420
++E R++IHRDL A N LV + K+ADFGLARL+ D+ YTA GAKFPIKWTAPE +
Sbjct: 356 VFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAI 415
Query: 421 AYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
Y TF+ KSDVW+FGILL EI T+G PYPG+ +V LE+
Sbjct: 416 NYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNLEVIQNLER 458
>X14055-1|CAA32211.1| 509|Homo sapiens protein ( Human
lymphocyte-specific protein tyrosine kinase (lck) gene,
exon 12. ).
Length = 509
Score = 320 bits (785), Expect = 9e-87
Identities = 179/403 (44%), Positives = 255/403 (63%), Gaps = 24/403 (5%)
Query: 73 LFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTLT-GAVGWVPSNYVTPVNSL 131
L +AL+ ++ + L +KGEQ+RI+ +SGEW +A +LT G G++P N+V NSL
Sbjct: 65 LVIALHSYEPSHDGDLGFEKGEQLRILE--QSGEWWKAQSLTTGQEGFIPFNFVAKANSL 122
Query: 132 EKHSWYHGPISRNAAE-YLLSSG-INGSFLVRESESSPGQRSISLR----YEGRVY-HYR 184
E W+ +SR AE LL+ G +GSFL+RESES+ G S+S+R +G V HY+
Sbjct: 123 EPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQNQGEVVKHYK 182
Query: 185 INEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKPTVFPLAP--PDH 242
I +G Y++ F L ELV H++ A DGL T+L P + P P D
Sbjct: 183 IRNLDNGGFYISPRITFPGLHELVRHYTNASDGLCTRLSRPCQTQK-----PQKPWWEDE 237
Query: 243 WEIDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASIMKEMR 302
WE+ R + + +LG GQ+G+V+ + G+ VAVK+LK +M+ FL EA++MK+++
Sbjct: 238 WEVPRETLKLVERLGAGQFGEVW-MGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQ 296
Query: 303 HPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLR--AGARECVPGAVVLMYMATQIASGM 360
H LV+L V T+EP YIITE+M G+L+++L+ +G + + L+ MA QIA GM
Sbjct: 297 HQRLVRLYAVVTQEP-IYIITEYMENGSLVDFLKTPSGIKLTINK---LLDMAAQIAEGM 352
Query: 361 SYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEGL 420
+++E R++IHRDL A N LV + K+ADFGLARL+ D+ YTA GAKFPIKWTAPE +
Sbjct: 353 AFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAI 412
Query: 421 AYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
Y TF+ KSDVW+FGILL EI T+G PYPG+ +V LE+
Sbjct: 413 NYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLER 455
>AL121991-2|CAI22320.1| 496|Homo sapiens lymphocyte-specific
protein tyrosine kinase protein.
Length = 496
Score = 320 bits (785), Expect = 9e-87
Identities = 179/403 (44%), Positives = 255/403 (63%), Gaps = 24/403 (5%)
Query: 73 LFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTLT-GAVGWVPSNYVTPVNSL 131
L +AL+ ++ + L +KGEQ+RI+ +SGEW +A +LT G G++P N+V NSL
Sbjct: 52 LVIALHSYEPSHDGDLGFEKGEQLRILE--QSGEWWKAQSLTTGQEGFIPFNFVAKANSL 109
Query: 132 EKHSWYHGPISRNAAE-YLLSSG-INGSFLVRESESSPGQRSISLR----YEGRVY-HYR 184
E W+ +SR AE LL+ G +GSFL+RESES+ G S+S+R +G V HY+
Sbjct: 110 EPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQNQGEVVKHYK 169
Query: 185 INEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKPTVFPLAP--PDH 242
I +G Y++ F L ELV H++ A DGL T+L P + P P D
Sbjct: 170 IRNLDNGGFYISPRITFPGLHELVRHYTNASDGLCTRLSRPCQTQK-----PQKPWWEDE 224
Query: 243 WEIDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASIMKEMR 302
WE+ R + + +LG GQ+G+V+ + G+ VAVK+LK +M+ FL EA++MK+++
Sbjct: 225 WEVPRETLKLVERLGAGQFGEVW-MGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQ 283
Query: 303 HPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLR--AGARECVPGAVVLMYMATQIASGM 360
H LV+L V T+EP YIITE+M G+L+++L+ +G + + L+ MA QIA GM
Sbjct: 284 HQRLVRLYAVVTQEP-IYIITEYMENGSLVDFLKTPSGIKLTINK---LLDMAAQIAEGM 339
Query: 361 SYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEGL 420
+++E R++IHRDL A N LV + K+ADFGLARL+ D+ YTA GAKFPIKWTAPE +
Sbjct: 340 AFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAI 399
Query: 421 AYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
Y TF+ KSDVW+FGILL EI T+G PYPG+ +V LE+
Sbjct: 400 NYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLER 442
>AF228313-1|AAF34794.1| 496|Homo sapiens tyrosine kinase LCK
protein.
Length = 496
Score = 320 bits (785), Expect = 9e-87
Identities = 179/403 (44%), Positives = 255/403 (63%), Gaps = 24/403 (5%)
Query: 73 LFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTLT-GAVGWVPSNYVTPVNSL 131
L +AL+ ++ + L +KGEQ+RI+ +SGEW +A +LT G G++P N+V NSL
Sbjct: 52 LVIALHSYEPSHDGDLGFEKGEQLRILE--QSGEWWKAQSLTTGQEGFIPFNFVAKANSL 109
Query: 132 EKHSWYHGPISRNAAE-YLLSSG-INGSFLVRESESSPGQRSISLR----YEGRVY-HYR 184
E W+ +SR AE LL+ G +GSFL+RESES+ G S+S+R +G V HY+
Sbjct: 110 EPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQNQGEVVKHYK 169
Query: 185 INEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKPTVFPLAP--PDH 242
I +G Y++ F L ELV H++ A DGL T+L P + P P D
Sbjct: 170 IRNLDNGGFYISPRITFPGLHELVRHYTNASDGLCTRLSRPCQTQK-----PQKPWWEDE 224
Query: 243 WEIDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASIMKEMR 302
WE+ R + + +LG GQ+G+V+ + G+ VAVK+LK +M+ FL EA++MK+++
Sbjct: 225 WEVPRETLKLVERLGAGQFGEVW-MGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQ 283
Query: 303 HPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLR--AGARECVPGAVVLMYMATQIASGM 360
H LV+L V T+EP YIITE+M G+L+++L+ +G + + L+ MA QIA GM
Sbjct: 284 HQRLVRLYAVVTQEP-IYIITEYMENGSLVDFLKTPSGIKLTINK---LLDMAAQIAEGM 339
Query: 361 SYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEGL 420
+++E R++IHRDL A N LV + K+ADFGLARL+ D+ YTA GAKFPIKWTAPE +
Sbjct: 340 AFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAI 399
Query: 421 AYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
Y TF+ KSDVW+FGILL EI T+G PYPG+ +V LE+
Sbjct: 400 NYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLER 442
>M79321-1|AAB50019.1| 491|Homo sapiens Lyn B protein protein.
Length = 491
Score = 319 bits (784), Expect = 1e-86
Identities = 175/408 (42%), Positives = 258/408 (63%), Gaps = 23/408 (5%)
Query: 68 EDDPQLFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTL-TGAVGWVPSNYVT 126
E+ + VALY + + L+ KKGE+++++ + GEW +A +L T G++PSNYV
Sbjct: 41 EEQGDIVVALYPYDGIHPDDLSFKKGEKMKVLE--EHGEWWKAKSLLTKKEGFIPSNYVA 98
Query: 127 PVNSLEKHSWYHGPISRNAAE-YLLSSGIN-GSFLVRESESSPGQRSISLRYEGRVY--- 181
+N+LE W+ I+R AE LL+ G + G+FL+RESE+ G S+S+R V+
Sbjct: 99 KLNTLETEEWFFKDITRKDAERQLLAPGNSAGAFLIRESETLKGSFSLSVRDFDPVHGDV 158
Query: 182 --HYRINEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYP--APKRSKPTVFPL 237
HY+I +G Y++ F +++++ H+ DGL +L +PK KP
Sbjct: 159 IKHYKIRSLDNGGYYISPRITFPCISDMIKHYQKQADGLCRRLEKACISPKPQKPW---- 214
Query: 238 APPDHWEIDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASI 297
D WEI R I + +LG GQ+G+V+ + + VAVKTLK TM+++ FLEEA++
Sbjct: 215 -DKDAWEIPRESIKLVKRLGAGQFGEVW-MGYYNNSTKVAVKTLKPGTMSVQAFLEEANL 272
Query: 298 MKEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRA--GARECVPGAVVLMYMATQ 355
MK ++H LV+L V TRE P YIITE+M++G+LL++L++ G + +P L+ + Q
Sbjct: 273 MKTLQHDKLVRLYAVVTREEPIYIITEYMAKGSLLDFLKSDEGGKVLLPK---LIDFSAQ 329
Query: 356 IASGMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWT 415
IA GM+Y+E +++IHRDL A N LV E+ + K+ADFGLAR++ D+ YTA GAKFPIKWT
Sbjct: 330 IAEGMAYIERKNYIHRDLRAANVLVSESLMCKIADFGLARVIEDNEYTAREGAKFPIKWT 389
Query: 416 APEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
APE + + F+ KSDVW+FGILL+EI TYG PYPG ADV L +
Sbjct: 390 APEAINFGCFTIKSDVWSFGILLYEIVTYGKIPYPGRTNADVMTALSQ 437
>M16038-1|AAA59540.1| 512|Homo sapiens LYN protein.
Length = 512
Score = 319 bits (784), Expect = 1e-86
Identities = 175/408 (42%), Positives = 258/408 (63%), Gaps = 23/408 (5%)
Query: 68 EDDPQLFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTL-TGAVGWVPSNYVT 126
E+ + VALY + + L+ KKGE+++++ + GEW +A +L T G++PSNYV
Sbjct: 62 EEQGDIVVALYPYDGIHPDDLSFKKGEKMKVLE--EHGEWWKAKSLLTKKEGFIPSNYVA 119
Query: 127 PVNSLEKHSWYHGPISRNAAE-YLLSSGIN-GSFLVRESESSPGQRSISLRYEGRVY--- 181
+N+LE W+ I+R AE LL+ G + G+FL+RESE+ G S+S+R V+
Sbjct: 120 KLNTLETEEWFFKDITRKDAERQLLAPGNSAGAFLIRESETLKGSFSLSVRDFDPVHGDV 179
Query: 182 --HYRINEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYP--APKRSKPTVFPL 237
HY+I +G Y++ F +++++ H+ DGL +L +PK KP
Sbjct: 180 IKHYKIRSLDNGGYYISPRITFPCISDMIKHYQKQADGLCRRLEKACISPKPQKPW---- 235
Query: 238 APPDHWEIDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASI 297
D WEI R I + +LG GQ+G+V+ + + VAVKTLK TM+++ FLEEA++
Sbjct: 236 -DKDAWEIPRESIKLVKRLGAGQFGEVW-MGYYNNSTKVAVKTLKPGTMSVQAFLEEANL 293
Query: 298 MKEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRA--GARECVPGAVVLMYMATQ 355
MK ++H LV+L V TRE P YIITE+M++G+LL++L++ G + +P L+ + Q
Sbjct: 294 MKTLQHDKLVRLYAVVTREEPIYIITEYMAKGSLLDFLKSDEGGKVLLPK---LIDFSAQ 350
Query: 356 IASGMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWT 415
IA GM+Y+E +++IHRDL A N LV E+ + K+ADFGLAR++ D+ YTA GAKFPIKWT
Sbjct: 351 IAEGMAYIERKNYIHRDLRAANVLVSESLMCKIADFGLARVIEDNEYTAREGAKFPIKWT 410
Query: 416 APEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
APE + + F+ KSDVW+FGILL+EI TYG PYPG ADV L +
Sbjct: 411 APEAINFGCFTIKSDVWSFGILLYEIVTYGKIPYPGRTNADVMTALSQ 458
>BC126458-1|AAI26459.1| 512|Homo sapiens LYN protein protein.
Length = 512
Score = 319 bits (784), Expect = 1e-86
Identities = 175/408 (42%), Positives = 258/408 (63%), Gaps = 23/408 (5%)
Query: 68 EDDPQLFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTL-TGAVGWVPSNYVT 126
E+ + VALY + + L+ KKGE+++++ + GEW +A +L T G++PSNYV
Sbjct: 62 EEQGDIVVALYPYDGIHPDDLSFKKGEKMKVLE--EHGEWWKAKSLLTKKEGFIPSNYVA 119
Query: 127 PVNSLEKHSWYHGPISRNAAE-YLLSSGIN-GSFLVRESESSPGQRSISLRYEGRVY--- 181
+N+LE W+ I+R AE LL+ G + G+FL+RESE+ G S+S+R V+
Sbjct: 120 KLNTLETEEWFFKDITRKDAERQLLAPGNSAGAFLIRESETLKGSFSLSVRDFDPVHGDV 179
Query: 182 --HYRINEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYP--APKRSKPTVFPL 237
HY+I +G Y++ F +++++ H+ DGL +L +PK KP
Sbjct: 180 IKHYKIRSLDNGGYYISPRITFPCISDMIKHYQKQADGLCRRLEKACISPKPQKPW---- 235
Query: 238 APPDHWEIDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASI 297
D WEI R I + +LG GQ+G+V+ + + VAVKTLK TM+++ FLEEA++
Sbjct: 236 -DKDAWEIPRESIKLVKRLGAGQFGEVW-MGYYNNSTKVAVKTLKPGTMSVQAFLEEANL 293
Query: 298 MKEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRA--GARECVPGAVVLMYMATQ 355
MK ++H LV+L V TRE P YIITE+M++G+LL++L++ G + +P L+ + Q
Sbjct: 294 MKTLQHDKLVRLYAVVTREEPIYIITEYMAKGSLLDFLKSDEGGKVLLPK---LIDFSAQ 350
Query: 356 IASGMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWT 415
IA GM+Y+E +++IHRDL A N LV E+ + K+ADFGLAR++ D+ YTA GAKFPIKWT
Sbjct: 351 IAEGMAYIERKNYIHRDLRAANVLVSESLMCKIADFGLARVIEDNEYTAREGAKFPIKWT 410
Query: 416 APEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
APE + + F+ KSDVW+FGILL+EI TYG PYPG ADV L +
Sbjct: 411 APEAINFGCFTIKSDVWSFGILLYEIVTYGKIPYPGRTNADVMTALSQ 458
>BC126456-1|AAI26457.1| 512|Homo sapiens LYN protein protein.
Length = 512
Score = 319 bits (784), Expect = 1e-86
Identities = 175/408 (42%), Positives = 258/408 (63%), Gaps = 23/408 (5%)
Query: 68 EDDPQLFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTL-TGAVGWVPSNYVT 126
E+ + VALY + + L+ KKGE+++++ + GEW +A +L T G++PSNYV
Sbjct: 62 EEQGDIVVALYPYDGIHPDDLSFKKGEKMKVLE--EHGEWWKAKSLLTKKEGFIPSNYVA 119
Query: 127 PVNSLEKHSWYHGPISRNAAE-YLLSSGIN-GSFLVRESESSPGQRSISLRYEGRVY--- 181
+N+LE W+ I+R AE LL+ G + G+FL+RESE+ G S+S+R V+
Sbjct: 120 KLNTLETEEWFFKDITRKDAERQLLAPGNSAGAFLIRESETLKGSFSLSVRDFDPVHGDV 179
Query: 182 --HYRINEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYP--APKRSKPTVFPL 237
HY+I +G Y++ F +++++ H+ DGL +L +PK KP
Sbjct: 180 IKHYKIRSLDNGGYYISPRITFPCISDMIKHYQKQADGLCRRLEKACISPKPQKPW---- 235
Query: 238 APPDHWEIDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASI 297
D WEI R I + +LG GQ+G+V+ + + VAVKTLK TM+++ FLEEA++
Sbjct: 236 -DKDAWEIPRESIKLVKRLGAGQFGEVW-MGYYNNSTKVAVKTLKPGTMSVQAFLEEANL 293
Query: 298 MKEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRA--GARECVPGAVVLMYMATQ 355
MK ++H LV+L V TRE P YIITE+M++G+LL++L++ G + +P L+ + Q
Sbjct: 294 MKTLQHDKLVRLYAVVTREEPIYIITEYMAKGSLLDFLKSDEGGKVLLPK---LIDFSAQ 350
Query: 356 IASGMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWT 415
IA GM+Y+E +++IHRDL A N LV E+ + K+ADFGLAR++ D+ YTA GAKFPIKWT
Sbjct: 351 IAEGMAYIERKNYIHRDLRAANVLVSESLMCKIADFGLARVIEDNEYTAREGAKFPIKWT 410
Query: 416 APEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
APE + + F+ KSDVW+FGILL+EI TYG PYPG ADV L +
Sbjct: 411 APEAINFGCFTIKSDVWSFGILLYEIVTYGKIPYPGRTNADVMTALSQ 458
>BC075002-1|AAH75002.1| 512|Homo sapiens v-yes-1 Yamaguchi sarcoma
viral related oncogene homolog protein.
Length = 512
Score = 319 bits (784), Expect = 1e-86
Identities = 175/408 (42%), Positives = 258/408 (63%), Gaps = 23/408 (5%)
Query: 68 EDDPQLFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTL-TGAVGWVPSNYVT 126
E+ + VALY + + L+ KKGE+++++ + GEW +A +L T G++PSNYV
Sbjct: 62 EEQGDIVVALYPYDGIHPDDLSFKKGEKMKVLE--EHGEWWKAKSLLTKKEGFIPSNYVA 119
Query: 127 PVNSLEKHSWYHGPISRNAAE-YLLSSGIN-GSFLVRESESSPGQRSISLRYEGRVY--- 181
+N+LE W+ I+R AE LL+ G + G+FL+RESE+ G S+S+R V+
Sbjct: 120 KLNTLETEEWFFKDITRKDAERQLLAPGNSAGAFLIRESETLKGSFSLSVRDFDPVHGDV 179
Query: 182 --HYRINEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYP--APKRSKPTVFPL 237
HY+I +G Y++ F +++++ H+ DGL +L +PK KP
Sbjct: 180 IKHYKIRSLDNGGYYISPRITFPCISDMIKHYQKQADGLCRRLEKACISPKPQKPW---- 235
Query: 238 APPDHWEIDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASI 297
D WEI R I + +LG GQ+G+V+ + + VAVKTLK TM+++ FLEEA++
Sbjct: 236 -DKDAWEIPRESIKLVKRLGAGQFGEVW-MGYYNNSTKVAVKTLKPGTMSVQAFLEEANL 293
Query: 298 MKEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRA--GARECVPGAVVLMYMATQ 355
MK ++H LV+L V TRE P YIITE+M++G+LL++L++ G + +P L+ + Q
Sbjct: 294 MKTLQHDKLVRLYAVVTREEPIYIITEYMAKGSLLDFLKSDEGGKVLLPK---LIDFSAQ 350
Query: 356 IASGMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWT 415
IA GM+Y+E +++IHRDL A N LV E+ + K+ADFGLAR++ D+ YTA GAKFPIKWT
Sbjct: 351 IAEGMAYIERKNYIHRDLRAANVLVSESLMCKIADFGLARVIEDNEYTAREGAKFPIKWT 410
Query: 416 APEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
APE + + F+ KSDVW+FGILL+EI TYG PYPG ADV L +
Sbjct: 411 APEAINFGCFTIKSDVWSFGILLYEIVTYGKIPYPGRTNADVMTALSQ 458
>BC075001-1|AAH75001.1| 512|Homo sapiens v-yes-1 Yamaguchi sarcoma
viral related oncogene homolog protein.
Length = 512
Score = 319 bits (784), Expect = 1e-86
Identities = 175/408 (42%), Positives = 258/408 (63%), Gaps = 23/408 (5%)
Query: 68 EDDPQLFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTL-TGAVGWVPSNYVT 126
E+ + VALY + + L+ KKGE+++++ + GEW +A +L T G++PSNYV
Sbjct: 62 EEQGDIVVALYPYDGIHPDDLSFKKGEKMKVLE--EHGEWWKAKSLLTKKEGFIPSNYVA 119
Query: 127 PVNSLEKHSWYHGPISRNAAE-YLLSSGIN-GSFLVRESESSPGQRSISLRYEGRVY--- 181
+N+LE W+ I+R AE LL+ G + G+FL+RESE+ G S+S+R V+
Sbjct: 120 KLNTLETEEWFFKDITRKDAERQLLAPGNSAGAFLIRESETLKGSFSLSVRDFDPVHGDV 179
Query: 182 --HYRINEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYP--APKRSKPTVFPL 237
HY+I +G Y++ F +++++ H+ DGL +L +PK KP
Sbjct: 180 IKHYKIRSLDNGGYYISPRITFPCISDMIKHYQKQADGLCRRLEKACISPKPQKPW---- 235
Query: 238 APPDHWEIDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASI 297
D WEI R I + +LG GQ+G+V+ + + VAVKTLK TM+++ FLEEA++
Sbjct: 236 -DKDAWEIPRESIKLVKRLGAGQFGEVW-MGYYNNSTKVAVKTLKPGTMSVQAFLEEANL 293
Query: 298 MKEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRA--GARECVPGAVVLMYMATQ 355
MK ++H LV+L V TRE P YIITE+M++G+LL++L++ G + +P L+ + Q
Sbjct: 294 MKTLQHDKLVRLYAVVTREEPIYIITEYMAKGSLLDFLKSDEGGKVLLPK---LIDFSAQ 350
Query: 356 IASGMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWT 415
IA GM+Y+E +++IHRDL A N LV E+ + K+ADFGLAR++ D+ YTA GAKFPIKWT
Sbjct: 351 IAEGMAYIERKNYIHRDLRAANVLVSESLMCKIADFGLARVIEDNEYTAREGAKFPIKWT 410
Query: 416 APEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
APE + + F+ KSDVW+FGILL+EI TYG PYPG ADV L +
Sbjct: 411 APEAINFGCFTIKSDVWSFGILLYEIVTYGKIPYPGRTNADVMTALSQ 458
>BC068551-1|AAH68551.1| 582|Homo sapiens LYN protein protein.
Length = 582
Score = 319 bits (784), Expect = 1e-86
Identities = 175/408 (42%), Positives = 258/408 (63%), Gaps = 23/408 (5%)
Query: 68 EDDPQLFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTL-TGAVGWVPSNYVT 126
E+ + VALY + + L+ KKGE+++++ + GEW +A +L T G++PSNYV
Sbjct: 132 EEQGDIVVALYPYDGIHPDDLSFKKGEKMKVLE--EHGEWWKAKSLLTKKEGFIPSNYVA 189
Query: 127 PVNSLEKHSWYHGPISRNAAE-YLLSSGIN-GSFLVRESESSPGQRSISLRYEGRVY--- 181
+N+LE W+ I+R AE LL+ G + G+FL+RESE+ G S+S+R V+
Sbjct: 190 KLNTLETEEWFFKDITRKDAERQLLAPGNSAGAFLIRESETLKGSFSLSVRDFDPVHGDV 249
Query: 182 --HYRINEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYP--APKRSKPTVFPL 237
HY+I +G Y++ F +++++ H+ DGL +L +PK KP
Sbjct: 250 IKHYKIRSLDNGGYYISPRITFPCISDMIKHYQKQADGLCRRLEKACISPKPQKPW---- 305
Query: 238 APPDHWEIDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASI 297
D WEI R I + +LG GQ+G+V+ + + VAVKTLK TM+++ FLEEA++
Sbjct: 306 -DKDAWEIPRESIKLVKRLGAGQFGEVW-MGYYNNSTKVAVKTLKPGTMSVQAFLEEANL 363
Query: 298 MKEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRA--GARECVPGAVVLMYMATQ 355
MK ++H LV+L V TRE P YIITE+M++G+LL++L++ G + +P L+ + Q
Sbjct: 364 MKTLQHDKLVRLYAVVTREEPIYIITEYMAKGSLLDFLKSDEGGKVLLPK---LIDFSAQ 420
Query: 356 IASGMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWT 415
IA GM+Y+E +++IHRDL A N LV E+ + K+ADFGLAR++ D+ YTA GAKFPIKWT
Sbjct: 421 IAEGMAYIERKNYIHRDLRAANVLVSESLMCKIADFGLARVIEDNEYTAREGAKFPIKWT 480
Query: 416 APEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
APE + + F+ KSDVW+FGILL+EI TYG PYPG ADV L +
Sbjct: 481 APEAINFGCFTIKSDVWSFGILLYEIVTYGKIPYPGRTNADVMTALSQ 528
>BC059394-1|AAH59394.1| 582|Homo sapiens LYN protein protein.
Length = 582
Score = 319 bits (784), Expect = 1e-86
Identities = 175/408 (42%), Positives = 258/408 (63%), Gaps = 23/408 (5%)
Query: 68 EDDPQLFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTL-TGAVGWVPSNYVT 126
E+ + VALY + + L+ KKGE+++++ + GEW +A +L T G++PSNYV
Sbjct: 132 EEQGDIVVALYPYDGIHPDDLSFKKGEKMKVLE--EHGEWWKAKSLLTKKEGFIPSNYVA 189
Query: 127 PVNSLEKHSWYHGPISRNAAE-YLLSSGIN-GSFLVRESESSPGQRSISLRYEGRVY--- 181
+N+LE W+ I+R AE LL+ G + G+FL+RESE+ G S+S+R V+
Sbjct: 190 KLNTLETEEWFFKDITRKDAERQLLAPGNSAGAFLIRESETLKGSFSLSVRDFDPVHGDV 249
Query: 182 --HYRINEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYP--APKRSKPTVFPL 237
HY+I +G Y++ F +++++ H+ DGL +L +PK KP
Sbjct: 250 IKHYKIRSLDNGGYYISPRITFPCISDMIKHYQKQADGLCRRLEKACISPKPQKPW---- 305
Query: 238 APPDHWEIDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASI 297
D WEI R I + +LG GQ+G+V+ + + VAVKTLK TM+++ FLEEA++
Sbjct: 306 -DKDAWEIPRESIKLVKRLGAGQFGEVW-MGYYNNSTKVAVKTLKPGTMSVQAFLEEANL 363
Query: 298 MKEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRA--GARECVPGAVVLMYMATQ 355
MK ++H LV+L V TRE P YIITE+M++G+LL++L++ G + +P L+ + Q
Sbjct: 364 MKTLQHDKLVRLYAVVTREEPIYIITEYMAKGSLLDFLKSDEGGKVLLPK---LIDFSAQ 420
Query: 356 IASGMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWT 415
IA GM+Y+E +++IHRDL A N LV E+ + K+ADFGLAR++ D+ YTA GAKFPIKWT
Sbjct: 421 IAEGMAYIERKNYIHRDLRAANVLVSESLMCKIADFGLARVIEDNEYTAREGAKFPIKWT 480
Query: 416 APEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
APE + + F+ KSDVW+FGILL+EI TYG PYPG ADV L +
Sbjct: 481 APEAINFGCFTIKSDVWSFGILLYEIVTYGKIPYPGRTNADVMTALSQ 528
>BC032413-1|AAH32413.1| 505|Homo sapiens B lymphoid tyrosine kinase
protein.
Length = 505
Score = 318 bits (782), Expect = 2e-86
Identities = 178/407 (43%), Positives = 255/407 (62%), Gaps = 20/407 (4%)
Query: 66 HEEDDPQLFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTL-TGAVGWVPSNY 124
H ++D VALYD+ A + L + KGE+++++ +G+W A +L TG G+VPSN+
Sbjct: 55 HLDEDKHFVVALYDYTAMNDRDLQMLKGEKLQVLK--GTGDWWLARSLVTGREGYVPSNF 112
Query: 125 VTPVNSLEKHSWYHGPISRNAAEYLLSSGIN--GSFLVRESESSPGQRSISLR---YEGR 179
V V SLE W+ R AE L + IN GSFL+RESE++ G S+S++ +G
Sbjct: 113 VARVESLEMERWFFRSQGRKEAERQLLAPINKAGSFLIRESETNKGAFSLSVKDVTTQGE 172
Query: 180 -VYHYRINEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKPTVFPLA 238
+ HY+I +G Y++ F +L LV H+S GDGL +L P + + P A
Sbjct: 173 LIKHYKIRCLDEGGYYISPRITFPSLQALVQHYSKKGDGLCQRLTLPCVRPAPQN--PWA 230
Query: 239 PPDHWEIDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASIM 298
D WEI R + + KLG GQ+G+V+ +K N+ VA+KTLK+ TM+ + FL EA++M
Sbjct: 231 Q-DEWEIPRQSLRLVRKLGSGQFGEVWMGYYKN-NMKVAIKTLKEGTMSPEAFLGEANVM 288
Query: 299 KEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRA--GARECVPGAVVLMYMATQI 356
K ++H LV+L V T+EP YI+TE+M+RG LL++L+ G+R +P L+ M+ QI
Sbjct: 289 KALQHERLVRLYAVVTKEP-IYIVTEYMARGCLLDFLKTDEGSRLSLPR---LIDMSAQI 344
Query: 357 ASGMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWTA 416
A GM+Y+E + IHRDL A N LV E K+ADFGLAR++ D YTA GAKFPIKWTA
Sbjct: 345 AEGMAYIERMNSIHRDLRAANILVSEALCCKIADFGLARII-DSEYTAQEGAKFPIKWTA 403
Query: 417 PEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
PE + + F+ K+DVW+FG+LL E+ TYG PYPG+ +V LE+
Sbjct: 404 PEAIHFGVFTIKADVWSFGVLLMEVVTYGRVPYPGMSNPEVIRNLER 450
>BC018703-1|AAH18703.1| 599|Homo sapiens Unknown (protein for
IMAGE:4574968) protein.
Length = 599
Score = 318 bits (782), Expect = 2e-86
Identities = 178/407 (43%), Positives = 255/407 (62%), Gaps = 20/407 (4%)
Query: 66 HEEDDPQLFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTL-TGAVGWVPSNY 124
H ++D VALYD+ A + L + KGE+++++ +G+W A +L TG G+VPSN+
Sbjct: 55 HLDEDKHFVVALYDYTAMNDRDLQMLKGEKLQVLK--GTGDWWLARSLVTGREGYVPSNF 112
Query: 125 VTPVNSLEKHSWYHGPISRNAAEYLLSSGIN--GSFLVRESESSPGQRSISLR---YEGR 179
V V SLE W+ R AE L + IN GSFL+RESE++ G S+S++ +G
Sbjct: 113 VARVESLEMERWFFRSQGRKEAERQLLAPINKAGSFLIRESETNKGAFSLSVKDVTTQGE 172
Query: 180 -VYHYRINEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKPTVFPLA 238
+ HY+I +G Y++ F +L LV H+S GDGL +L P + + P A
Sbjct: 173 LIKHYKIRCLDEGGYYISPRITFPSLQALVQHYSKKGDGLCQRLTLPCVRPAPQN--PWA 230
Query: 239 PPDHWEIDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASIM 298
D WEI R + + KLG GQ+G+V+ +K N+ VA+KTLK+ TM+ + FL EA++M
Sbjct: 231 Q-DEWEIPRQSLRLVRKLGSGQFGEVWMGYYKN-NMKVAIKTLKEGTMSPEAFLGEANVM 288
Query: 299 KEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRA--GARECVPGAVVLMYMATQI 356
K ++H LV+L V T+EP YI+TE+M+RG LL++L+ G+R +P L+ M+ QI
Sbjct: 289 KALQHERLVRLYAVVTKEP-IYIVTEYMARGCLLDFLKTDEGSRLSLPR---LIDMSAQI 344
Query: 357 ASGMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWTA 416
A GM+Y+E + IHRDL A N LV E K+ADFGLAR++ D YTA GAKFPIKWTA
Sbjct: 345 AEGMAYIERMNSIHRDLRAANILVSEALCCKIADFGLARII-DSEYTAQEGAKFPIKWTA 403
Query: 417 PEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
PE + + F+ K+DVW+FG+LL E+ TYG PYPG+ +V LE+
Sbjct: 404 PEAIHFGVFTIKADVWSFGVLLMEVVTYGRVPYPGMSNPEVIRNLER 450
>BC007371-1|AAH07371.1| 505|Homo sapiens B lymphoid tyrosine kinase
protein.
Length = 505
Score = 318 bits (782), Expect = 2e-86
Identities = 178/407 (43%), Positives = 255/407 (62%), Gaps = 20/407 (4%)
Query: 66 HEEDDPQLFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTL-TGAVGWVPSNY 124
H ++D VALYD+ A + L + KGE+++++ +G+W A +L TG G+VPSN+
Sbjct: 55 HLDEDKHFVVALYDYTAMNDRDLQMLKGEKLQVLK--GTGDWWLARSLVTGREGYVPSNF 112
Query: 125 VTPVNSLEKHSWYHGPISRNAAEYLLSSGIN--GSFLVRESESSPGQRSISLR---YEGR 179
V V SLE W+ R AE L + IN GSFL+RESE++ G S+S++ +G
Sbjct: 113 VARVESLEMERWFFRSQGRKEAERQLLAPINKAGSFLIRESETNKGAFSLSVKDVTTQGE 172
Query: 180 -VYHYRINEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKPTVFPLA 238
+ HY+I +G Y++ F +L LV H+S GDGL +L P + + P A
Sbjct: 173 LIKHYKIRCLDEGGYYISPRITFPSLQALVQHYSKKGDGLCQRLTLPCVRPAPQN--PWA 230
Query: 239 PPDHWEIDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASIM 298
D WEI R + + KLG GQ+G+V+ +K N+ VA+KTLK+ TM+ + FL EA++M
Sbjct: 231 Q-DEWEIPRQSLRLVRKLGSGQFGEVWMGYYKN-NMKVAIKTLKEGTMSPEAFLGEANVM 288
Query: 299 KEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRA--GARECVPGAVVLMYMATQI 356
K ++H LV+L V T+EP YI+TE+M+RG LL++L+ G+R +P L+ M+ QI
Sbjct: 289 KALQHERLVRLYAVVTKEP-IYIVTEYMARGCLLDFLKTDEGSRLSLPR---LIDMSAQI 344
Query: 357 ASGMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWTA 416
A GM+Y+E + IHRDL A N LV E K+ADFGLAR++ D YTA GAKFPIKWTA
Sbjct: 345 AEGMAYIERMNSIHRDLRAANILVSEALCCKIADFGLARII-DSEYTAQEGAKFPIKWTA 403
Query: 417 PEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
PE + + F+ K+DVW+FG+LL E+ TYG PYPG+ +V LE+
Sbjct: 404 PEAIHFGVFTIKADVWSFGVLLMEVVTYGRVPYPGMSNPEVIRNLER 450
>Z33998-1|CAA83965.1| 505|Homo sapiens Protein-Tyrosine Kinase
protein.
Length = 505
Score = 318 bits (780), Expect = 4e-86
Identities = 178/407 (43%), Positives = 255/407 (62%), Gaps = 20/407 (4%)
Query: 66 HEEDDPQLFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTL-TGAVGWVPSNY 124
H ++D VALYD+ A + L + KGE+++++ +G+W A +L TG G+VPSN+
Sbjct: 55 HLDEDKHFVVALYDYTAMNDRDLQMLKGEKLQVLK--GTGDWWLARSLVTGREGYVPSNF 112
Query: 125 VTPVNSLEKHSWYHGPISRNAAEYLLSSGIN--GSFLVRESESSPGQRSISLR---YEGR 179
V V SLE W+ R AE L + IN GSFL+RESE++ G S+S++ +G
Sbjct: 113 VARVESLEMERWFFRSQGRKEAERQLLAPINKAGSFLIRESETNKGAFSLSVKDVTTQGE 172
Query: 180 -VYHYRINEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKPTVFPLA 238
+ HY+I +G Y++ F +L LV H+S GDGL +L P + + P A
Sbjct: 173 LIKHYKIRCLDEGGYYISPRITFPSLQALVQHYSKKGDGLCQRLTLPCVRPAPQN--PWA 230
Query: 239 PPDHWEIDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASIM 298
D WEI R + + KLG GQ+G+V+ +K N+ VA+KTLK+ TM+ + FL EA++M
Sbjct: 231 Q-DEWEIPRQSLRLVRKLGSGQFGEVWMGYYKN-NMKVAIKTLKEGTMSPEAFLGEANMM 288
Query: 299 KEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRA--GARECVPGAVVLMYMATQI 356
K ++H LV+L V T+EP YI+TE+M+RG LL++L+ G+R +P L+ M+ QI
Sbjct: 289 KALQHERLVRLYAVVTKEP-IYIVTEYMARGCLLDFLKTDEGSRLSLPR---LIDMSAQI 344
Query: 357 ASGMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWTA 416
A GM+Y+E + IHRDL A N LV E K+ADFGLAR++ D YTA GAKFPIKWTA
Sbjct: 345 AEGMAYIERMNSIHRDLRAANILVSEALCCKIADFGLARII-DSEYTAQEGAKFPIKWTA 403
Query: 417 PEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
PE + + F+ K+DVW+FG+LL E+ TYG PYPG+ +V LE+
Sbjct: 404 PEAIHFGVFTIKADVWSFGVLLMEVVTYGRVPYPGMSNPEVIRNLER 450
>X13529-1|CAA31884.1| 509|Homo sapiens protein ( Human lck mRNA for
membrane associated protein tyrosine kinase. ).
Length = 509
Score = 317 bits (779), Expect = 5e-86
Identities = 178/403 (44%), Positives = 254/403 (63%), Gaps = 24/403 (5%)
Query: 73 LFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTLT-GAVGWVPSNYVTPVNSL 131
L +AL+ ++ + L +KGE +RI+ +SGEW +A +LT G G++P N+V NSL
Sbjct: 65 LVIALHSYEPSHDGDLGFEKGEPLRILE--QSGEWWKAQSLTTGQEGFIPFNFVAKANSL 122
Query: 132 EKHSWYHGPISRNAAE-YLLSSG-INGSFLVRESESSPGQRSISLR----YEGRVY-HYR 184
E W+ +SR AE LL+ G +GSFL+RESES+ G S+S+R +G V HY+
Sbjct: 123 EPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQNQGEVVKHYK 182
Query: 185 INEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKPTVFPLAP--PDH 242
I +G Y++ F L ELV H++ A DGL T+L P + P P D
Sbjct: 183 IRNLDNGGFYISPRITFPGLHELVRHYTNASDGLCTRLSRPCQTQK-----PQKPWWEDE 237
Query: 243 WEIDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASIMKEMR 302
WE+ R + + +LG GQ+G+V+ + G+ VAVK+LK +M+ FL EA++MK+++
Sbjct: 238 WEVPRETLKLVERLGAGQFGEVW-MGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQ 296
Query: 303 HPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLR--AGARECVPGAVVLMYMATQIASGM 360
H LV+L V T+EP YIITE+M G+L+++L+ +G + + L+ MA QIA GM
Sbjct: 297 HQRLVRLYAVVTQEP-IYIITEYMENGSLVDFLKTPSGIKLTINK---LLDMAAQIAEGM 352
Query: 361 SYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEGL 420
+++E R++IHRDL A N LV + K+ADFGLARL+ D+ YTA GAKFPIKWTAPE +
Sbjct: 353 AFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAI 412
Query: 421 AYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
Y TF+ KSDVW+FGILL EI T+G PYPG+ +V LE+
Sbjct: 413 NYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLER 455
>S76617-1|AAB33265.1| 505|Homo sapiens blk protein.
Length = 505
Score = 317 bits (779), Expect = 5e-86
Identities = 178/407 (43%), Positives = 254/407 (62%), Gaps = 20/407 (4%)
Query: 66 HEEDDPQLFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTL-TGAVGWVPSNY 124
H ++D VALYD+ A + L + KGE+++++ +G+W A +L TG G+VPSN+
Sbjct: 55 HLDEDKHFVVALYDYTAMNDRDLQMLKGEKLQVLK--GTGDWWLARSLVTGREGYVPSNF 112
Query: 125 VTPVNSLEKHSWYHGPISRNAAEYLLSSGIN--GSFLVRESESSPGQRSISLR---YEGR 179
V V SLE W+ R AE L + IN GSFL+RESE++ G S+S++ +G
Sbjct: 113 VARVESLEMERWFFRSQGRKEAERQLLAPINKAGSFLIRESETNKGAFSLSVKDVTTQGE 172
Query: 180 -VYHYRINEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKPTVFPLA 238
+ HY+I +G Y++ F +L LV H+S GDGL +L P + + P A
Sbjct: 173 LIKHYKIRCLDEGGYYISPRITFPSLQALVQHYSKKGDGLCQRLTLPCVRPAPQN--PWA 230
Query: 239 PPDHWEIDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASIM 298
D WEI R + + KLG GQ+G+V+ +K N+ VA+KTLK+ TM+ + FL EA++M
Sbjct: 231 Q-DEWEIPRQSLRLVRKLGSGQFGEVWMGYYKN-NMKVAIKTLKEGTMSPEAFLGEANVM 288
Query: 299 KEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRA--GARECVPGAVVLMYMATQI 356
K ++H LV+L V T+EP YI+TE+M+RG LL++L+ G+R +P L+ M+ QI
Sbjct: 289 KALQHERLVRLYAVVTKEP-IYIVTEYMARGCLLDFLKTDEGSRLSLPR---LIDMSAQI 344
Query: 357 ASGMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWTA 416
A GM+Y+E + IHRDL A N LV E K+ADFGLAR++ D YTA GAKFPIKWTA
Sbjct: 345 AEGMAYIERMNSIHRDLRAANILVSEALCCKIADFGLARII-DSEYTAQEGAKFPIKWTA 403
Query: 417 PEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
PE + F+ K+DVW+FG+LL E+ TYG PYPG+ +V LE+
Sbjct: 404 PEAYHFGVFTIKADVWSFGVLLMEVVTYGRVPYPGMSNPEVIRNLER 450
>M36881-1|AAA59502.1| 509|Homo sapiens lymphocyte-specific protein
tyrosine kinase protein.
Length = 509
Score = 315 bits (773), Expect = 3e-85
Identities = 177/403 (43%), Positives = 253/403 (62%), Gaps = 24/403 (5%)
Query: 73 LFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTLT-GAVGWVPSNYVTPVNSL 131
L +AL+ ++ + L +KGE +RI+ +SGEW +A +LT G G++P N+V NSL
Sbjct: 65 LVIALHSYEPSHDGDLGFEKGEPLRILE--QSGEWWKAQSLTTGQEGFIPFNFVAKANSL 122
Query: 132 EKHSWYHGPISRNAAE-YLLSSG-INGSFLVRESESSPGQRSISLR----YEGRVY-HYR 184
E W+ +SR AE LL+ G +GSFL+RESES+ G S+S+R +G V HY+
Sbjct: 123 EPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQNQGEVVKHYK 182
Query: 185 INEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKPTVFPLAP--PDH 242
I +G Y++ F L ELV H++ A DGL T+L P + P P D
Sbjct: 183 IRNLDNGGFYISPRITFPGLHELVRHYTNASDGLCTRLSRPCQTQK-----PQKPWWEDE 237
Query: 243 WEIDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASIMKEMR 302
WE+ R + + +LG Q+G+V+ + G+ VAVK+LK +M+ FL EA++MK+++
Sbjct: 238 WEVPRETLKLVERLGAAQFGEVW-MGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQ 296
Query: 303 HPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLR--AGARECVPGAVVLMYMATQIASGM 360
H LV+L V T+EP YIITE+M G+L+++L+ +G + + L+ MA QIA GM
Sbjct: 297 HQRLVRLYAVVTQEP-IYIITEYMENGSLVDFLKTPSGIKLTINK---LLDMAAQIAEGM 352
Query: 361 SYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEGL 420
+++E R++IHRDL A N LV + K+ADFGLARL+ D+ YTA GAKFPIKWTAPE +
Sbjct: 353 AFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAI 412
Query: 421 AYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
Y TF+ KSDVW+FGILL EI T+G PYPG+ +V LE+
Sbjct: 413 NYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLER 455
>BC101713-1|AAI01714.1| 631|Homo sapiens tec protein tyrosine
kinase protein.
Length = 631
Score = 315 bits (773), Expect = 3e-85
Identities = 166/396 (41%), Positives = 242/396 (61%), Gaps = 19/396 (4%)
Query: 67 EEDDPQLFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTLTGAVGWVPSNYVT 126
E++ ++ VA+YDFQA + L L++G++ I+ N W A G G++PSNYVT
Sbjct: 177 EDNSEEIVVAMYDFQAAEGHDLRLERGQEYLILEKNDV-HWWRARDKYGNEGYIPSNYVT 235
Query: 127 --PVNSLEKHSWYHGPISRNAAEYLL-SSGINGSFLVRESESSPGQRSISL--RYEG--- 178
N+L+++ WY ++R+ AE LL S G F+VR+S S PG ++SL ++ G
Sbjct: 236 GKKSNNLDQYEWYCRNMNRSKAEQLLRSEDKEGGFMVRDS-SQPGLYTVSLYTKFGGEGS 294
Query: 179 ---RVYHYRINEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSK--PT 233
R YH + + K Y+ + FG++ E++ +H GL+T+L YP + K PT
Sbjct: 295 SGFRHYHIKETTTSPKKYYLAEKHAFGSIPEIIEYHKHNAAGLVTRLRYPVSVKGKNAPT 354
Query: 234 VFPLAPPDHWEIDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLE 293
+ + WEI+ +++ +LG G +G V W R VA+K +++ M +DF+E
Sbjct: 355 TAGFSY-EKWEINPSELTFMRELGSGLFGVVRLGKW-RAQYKVAIKAIREGAMCEEDFIE 412
Query: 294 EASIMKEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMA 353
EA +M ++ HP LVQL GVCT++ P YI+TEFM RG LL +LR R+ VL+ M
Sbjct: 413 EAKVMMKLTHPKLVQLYGVCTQQKPIYIVTEFMERGCLLNFLRQ--RQGHFSRDVLLSMC 470
Query: 354 TQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIK 413
+ GM YLE SFIHRDLAARNCLV E +VKV+DFG+AR + DD YT+ +GAKFP+K
Sbjct: 471 QDVCEGMEYLERNSFIHRDLAARNCLVSEAGVVKVSDFGMARYVLDDQYTSSSGAKFPVK 530
Query: 414 WTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPY 449
W PE Y+ FS+KSDVW+FG+L+WE+ T G P+
Sbjct: 531 WCPPEVFNYSRFSSKSDVWSFGVLMWEVFTEGRMPF 566
>BC101711-1|AAI01712.1| 631|Homo sapiens tec protein tyrosine
kinase protein.
Length = 631
Score = 315 bits (773), Expect = 3e-85
Identities = 166/396 (41%), Positives = 242/396 (61%), Gaps = 19/396 (4%)
Query: 67 EEDDPQLFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTLTGAVGWVPSNYVT 126
E++ ++ VA+YDFQA + L L++G++ I+ N W A G G++PSNYVT
Sbjct: 177 EDNSEEIVVAMYDFQAAEGHDLRLERGQEYLILEKNDV-HWWRARDKYGNEGYIPSNYVT 235
Query: 127 --PVNSLEKHSWYHGPISRNAAEYLL-SSGINGSFLVRESESSPGQRSISL--RYEG--- 178
N+L+++ WY ++R+ AE LL S G F+VR+S S PG ++SL ++ G
Sbjct: 236 GKKSNNLDQYEWYCRNMNRSKAEQLLRSEDKEGGFMVRDS-SQPGLYTVSLYTKFGGEGS 294
Query: 179 ---RVYHYRINEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSK--PT 233
R YH + + K Y+ + FG++ E++ +H GL+T+L YP + K PT
Sbjct: 295 SGFRHYHIKETTTSPKKYYLAEKHAFGSIPEIIEYHKHNAAGLVTRLRYPVSVKGKNAPT 354
Query: 234 VFPLAPPDHWEIDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLE 293
+ + WEI+ +++ +LG G +G V W R VA+K +++ M +DF+E
Sbjct: 355 TAGFSY-EKWEINPSELTFMRELGSGLFGVVRLGKW-RAQYKVAIKAIREGAMCEEDFIE 412
Query: 294 EASIMKEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMA 353
EA +M ++ HP LVQL GVCT++ P YI+TEFM RG LL +LR R+ VL+ M
Sbjct: 413 EAKVMMKLTHPKLVQLYGVCTQQKPIYIVTEFMERGCLLNFLRQ--RQGHFSRDVLLSMC 470
Query: 354 TQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIK 413
+ GM YLE SFIHRDLAARNCLV E +VKV+DFG+AR + DD YT+ +GAKFP+K
Sbjct: 471 QDVCEGMEYLERNSFIHRDLAARNCLVSEAGVVKVSDFGMARYVLDDQYTSSSGAKFPVK 530
Query: 414 WTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPY 449
W PE Y+ FS+KSDVW+FG+L+WE+ T G P+
Sbjct: 531 WCPPEVFNYSRFSSKSDVWSFGVLMWEVFTEGRMPF 566
>D29767-1|BAA06171.1| 631|Homo sapiens Tec protein-tyrosine kinase
protein.
Length = 631
Score = 314 bits (772), Expect = 3e-85
Identities = 166/396 (41%), Positives = 241/396 (60%), Gaps = 19/396 (4%)
Query: 67 EEDDPQLFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTLTGAVGWVPSNYVT 126
E++ ++ VA+YDFQA + L L++G++ I+ N W A G G++PSNYVT
Sbjct: 177 EDNSEEIVVAMYDFQAAEGHDLRLERGQEYLILEKNDV-HWWRARDKYGNEGYIPSNYVT 235
Query: 127 --PVNSLEKHSWYHGPISRNAAEYLL-SSGINGSFLVRESESSPGQRSISL--RYEG--- 178
N+L+++ WY ++R+ AE LL S G F+VR+S S PG ++SL ++ G
Sbjct: 236 GKKSNNLDQYEWYCRNMNRSKAEQLLRSEDKEGGFMVRDS-SQPGLYTVSLYTKFGGEGS 294
Query: 179 ---RVYHYRINEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSK--PT 233
R YH + + K Y+ + FG++ E++ +H GL+T+L YP + K PT
Sbjct: 295 SGFRHYHIKETTTSPKKYYLAEKHAFGSIPEIIEYHKHNAAGLVTRLRYPVSVKGKNAPT 354
Query: 234 VFPLAPPDHWEIDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLE 293
+ + WEI+ +++ +LG G +G V W R VA+K +++ M +DF+E
Sbjct: 355 TAGFSY-EKWEINPSELTFMRELGSGLFGVVRLGKW-RAQYKVAIKAIREGAMCEEDFIE 412
Query: 294 EASIMKEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMA 353
EA +M ++ HP LVQL GVCT++ P YI+TEFM RG LL +LR R+ VL+ M
Sbjct: 413 EAKVMMKLTHPKLVQLYGVCTQQKPIYIVTEFMERGCLLNFLRQ--RQGHFSRDVLLSMC 470
Query: 354 TQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIK 413
+ GM YLE SFIHRDLAARNCLV E +VKV+DFG+AR DD YT+ +GAKFP+K
Sbjct: 471 QDVCEGMEYLERNSFIHRDLAARNCLVSEAGVVKVSDFGMARYFLDDQYTSSSGAKFPVK 530
Query: 414 WTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPY 449
W PE Y+ FS+KSDVW+FG+L+WE+ T G P+
Sbjct: 531 WCPPEVFNYSRFSSKSDVWSFGVLMWEVFTEGRMPF 566
>AJ131467-1|CAA10377.1| 307|Homo sapiens BCR/ABL chimeric fusion
peptide protein.
Length = 307
Score = 313 bits (768), Expect = 1e-84
Identities = 142/187 (75%), Positives = 161/187 (86%), Gaps = 1/187 (0%)
Query: 53 ANRWTSKENLLAHHEEDDPQLFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHT 112
A RW SKENLLA E+DP LFVALYDF A G+N L++ KGE++R++ YN +GEWCEA T
Sbjct: 118 AARWNSKENLLAGPSENDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQT 177
Query: 113 LTGAVGWVPSNYVTPVNSLEKHSWYHGPISRNAAEYLLSSGINGSFLVRESESSPGQRSI 172
G GWVPSNY+TPVNSLEKHSWYHGP+SRNAAEYLLSSGINGSFLVRESESSPGQRSI
Sbjct: 178 KNGQ-GWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSI 236
Query: 173 SLRYEGRVYHYRINEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKP 232
SLRYEGRVYHYRIN +DGK+YV+SES+F TLAELVHHHS DGLIT L YPAPKR+KP
Sbjct: 237 SLRYEGRVYHYRINTASDGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRNKP 296
Query: 233 TVFPLAP 239
TV+ ++P
Sbjct: 297 TVYGVSP 303
>AJ131466-1|CAA10376.1| 332|Homo sapiens BCR/ABL (major breakpoint)
fusion peptide protein.
Length = 332
Score = 313 bits (768), Expect = 1e-84
Identities = 142/187 (75%), Positives = 161/187 (86%), Gaps = 1/187 (0%)
Query: 53 ANRWTSKENLLAHHEEDDPQLFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHT 112
A RW SKENLLA E+DP LFVALYDF A G+N L++ KGE++R++ YN +GEWCEA T
Sbjct: 143 AARWNSKENLLAGPSENDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQT 202
Query: 113 LTGAVGWVPSNYVTPVNSLEKHSWYHGPISRNAAEYLLSSGINGSFLVRESESSPGQRSI 172
G GWVPSNY+TPVNSLEKHSWYHGP+SRNAAEYLLSSGINGSFLVRESESSPGQRSI
Sbjct: 203 KNGQ-GWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSI 261
Query: 173 SLRYEGRVYHYRINEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKP 232
SLRYEGRVYHYRIN +DGK+YV+SES+F TLAELVHHHS DGLIT L YPAPKR+KP
Sbjct: 262 SLRYEGRVYHYRINTASDGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRNKP 321
Query: 233 TVFPLAP 239
TV+ ++P
Sbjct: 322 TVYGVSP 328
>AF113911-1|AAD04633.1| 359|Homo sapiens BCR-ABL minor breakpoint
peptide protein.
Length = 359
Score = 313 bits (768), Expect = 1e-84
Identities = 142/187 (75%), Positives = 161/187 (86%), Gaps = 1/187 (0%)
Query: 53 ANRWTSKENLLAHHEEDDPQLFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHT 112
A RW SKENLLA E+DP LFVALYDF A G+N L++ KGE++R++ YN +GEWCEA T
Sbjct: 170 AARWNSKENLLAGPSENDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQT 229
Query: 113 LTGAVGWVPSNYVTPVNSLEKHSWYHGPISRNAAEYLLSSGINGSFLVRESESSPGQRSI 172
G GWVPSNY+TPVNSLEKHSWYHGP+SRNAAEYLLSSGINGSFLVRESESSPGQRSI
Sbjct: 230 KNGQ-GWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSI 288
Query: 173 SLRYEGRVYHYRINEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKP 232
SLRYEGRVYHYRIN +DGK+YV+SES+F TLAELVHHHS DGLIT L YPAPKR+KP
Sbjct: 289 SLRYEGRVYHYRINTASDGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRNKP 348
Query: 233 TVFPLAP 239
TV+ ++P
Sbjct: 349 TVYGVSP 355
>X58957-1|CAA41728.1| 659|Homo sapiens agammaglobulinaemia tyrosine
kinase protein.
Length = 659
Score = 301 bits (740), Expect = 2e-81
Identities = 158/385 (41%), Positives = 231/385 (60%), Gaps = 16/385 (4%)
Query: 75 VALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTLTGAVGWVPSNYVTPV-NSLEK 133
VALYD+ N L L+KG++ I+ + W A G G++PSNYVT +S+E
Sbjct: 220 VALYDYMPMNANDLQLRKGDEYFILEESNL-PWWRARDKNGQEGYIPSNYVTEAEDSIEM 278
Query: 134 HSWYHGPISRNAAEYLLSS-GINGSFLVRESESSPGQRSISLRY------EGRVYHYRIN 186
+ WY ++R+ AE LL G G F+VR+S S G+ ++S+ +G + HY +
Sbjct: 279 YEWYSKHMTRSQAEQLLKQEGKEGGFIVRDS-SKAGKYTVSVFAKSTGDPQGVIRHYVVC 337
Query: 187 EDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSK--PTVFPLAPPDHWE 244
+ Y+ + F T+ EL+++H GLI++L YP +++K P+ L WE
Sbjct: 338 STPQSQYYLAEKHLFSTIPELINYHQHNSAGLISRLKYPVSQQNKNAPSTAGLGYGS-WE 396
Query: 245 IDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASIMKEMRHP 304
ID D+ +LG GQ+G V W RG VA+K +K+ +M+ +F+EEA +M + H
Sbjct: 397 IDPKDLTFLKELGTGQFGVVKYGKW-RGQYDVAIKMIKEGSMSEDEFIEEAKVMMNLSHE 455
Query: 305 NLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIASGMSYLE 364
LVQL GVCT++ P +IITE+M+ G LL YLR L+ M + M YLE
Sbjct: 456 KLVQLYGVCTKQRPIFIITEYMANGCLLNYLREMRHRFQTQQ--LLEMCKDVCEAMEYLE 513
Query: 365 SRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEGLAYNT 424
S+ F+HRDLAARNCLV + +VKV+DFGL+R + DD YT+ G+KFP++W+ PE L Y+
Sbjct: 514 SKQFLHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDEYTSSVGSKFPVRWSPPEVLMYSK 573
Query: 425 FSTKSDVWAFGILLWEIATYGMSPY 449
FS+KSD+WAFG+L+WEI + G PY
Sbjct: 574 FSSKSDIWAFGVLMWEIYSLGKMPY 598
>U78027-4|AAB64205.1| 659|Homo sapiens Bruton's tyrosine kinase
protein.
Length = 659
Score = 301 bits (740), Expect = 2e-81
Identities = 158/385 (41%), Positives = 231/385 (60%), Gaps = 16/385 (4%)
Query: 75 VALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTLTGAVGWVPSNYVTPV-NSLEK 133
VALYD+ N L L+KG++ I+ + W A G G++PSNYVT +S+E
Sbjct: 220 VALYDYMPMNANDLQLRKGDEYFILEESNL-PWWRARDKNGQEGYIPSNYVTEAEDSIEM 278
Query: 134 HSWYHGPISRNAAEYLLSS-GINGSFLVRESESSPGQRSISLRY------EGRVYHYRIN 186
+ WY ++R+ AE LL G G F+VR+S S G+ ++S+ +G + HY +
Sbjct: 279 YEWYSKHMTRSQAEQLLKQEGKEGGFIVRDS-SKAGKYTVSVFAKSTGDPQGVIRHYVVC 337
Query: 187 EDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSK--PTVFPLAPPDHWE 244
+ Y+ + F T+ EL+++H GLI++L YP +++K P+ L WE
Sbjct: 338 STPQSQYYLAEKHLFSTIPELINYHQHNSAGLISRLKYPVSQQNKNAPSTAGLGYGS-WE 396
Query: 245 IDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASIMKEMRHP 304
ID D+ +LG GQ+G V W RG VA+K +K+ +M+ +F+EEA +M + H
Sbjct: 397 IDPKDLTFLKELGTGQFGVVKYGKW-RGQYDVAIKMIKEGSMSEDEFIEEAKVMMNLSHE 455
Query: 305 NLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIASGMSYLE 364
LVQL GVCT++ P +IITE+M+ G LL YLR L+ M + M YLE
Sbjct: 456 KLVQLYGVCTKQRPIFIITEYMANGCLLNYLREMRHRFQTQQ--LLEMCKDVCEAMEYLE 513
Query: 365 SRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEGLAYNT 424
S+ F+HRDLAARNCLV + +VKV+DFGL+R + DD YT+ G+KFP++W+ PE L Y+
Sbjct: 514 SKQFLHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDEYTSSVGSKFPVRWSPPEVLMYSK 573
Query: 425 FSTKSDVWAFGILLWEIATYGMSPY 449
FS+KSD+WAFG+L+WEI + G PY
Sbjct: 574 FSSKSDIWAFGVLMWEIYSLGKMPY 598
>U10087-1|AAB60639.1| 659|Homo sapiens Bruton agammaglobulinemia
tyrosine kinase protein.
Length = 659
Score = 301 bits (740), Expect = 2e-81
Identities = 158/385 (41%), Positives = 231/385 (60%), Gaps = 16/385 (4%)
Query: 75 VALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTLTGAVGWVPSNYVTPV-NSLEK 133
VALYD+ N L L+KG++ I+ + W A G G++PSNYVT +S+E
Sbjct: 220 VALYDYMPMNANDLQLRKGDEYFILEESNL-PWWRARDKNGQEGYIPSNYVTEAEDSIEM 278
Query: 134 HSWYHGPISRNAAEYLLSS-GINGSFLVRESESSPGQRSISLRY------EGRVYHYRIN 186
+ WY ++R+ AE LL G G F+VR+S S G+ ++S+ +G + HY +
Sbjct: 279 YEWYSKHMTRSQAEQLLKQEGKEGGFIVRDS-SKAGKYTVSVFAKSTGDPQGVIRHYVVC 337
Query: 187 EDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSK--PTVFPLAPPDHWE 244
+ Y+ + F T+ EL+++H GLI++L YP +++K P+ L WE
Sbjct: 338 STPQSQYYLAEKHLFSTIPELINYHQHNSAGLISRLKYPVSQQNKNAPSTAGLGYGS-WE 396
Query: 245 IDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASIMKEMRHP 304
ID D+ +LG GQ+G V W RG VA+K +K+ +M+ +F+EEA +M + H
Sbjct: 397 IDPKDLTFLKELGTGQFGVVKYGKW-RGQYDVAIKMIKEGSMSEDEFIEEAKVMMNLSHE 455
Query: 305 NLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIASGMSYLE 364
LVQL GVCT++ P +IITE+M+ G LL YLR L+ M + M YLE
Sbjct: 456 KLVQLYGVCTKQRPIFIITEYMANGCLLNYLREMRHRFQTQQ--LLEMCKDVCEAMEYLE 513
Query: 365 SRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEGLAYNT 424
S+ F+HRDLAARNCLV + +VKV+DFGL+R + DD YT+ G+KFP++W+ PE L Y+
Sbjct: 514 SKQFLHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDEYTSSVGSKFPVRWSPPEVLMYSK 573
Query: 425 FSTKSDVWAFGILLWEIATYGMSPY 449
FS+KSD+WAFG+L+WEI + G PY
Sbjct: 574 FSSKSDIWAFGVLMWEIYSLGKMPY 598
>L31572-1|AAA61479.1| 659|Homo sapiens Bruton agammaglobulinemia
protein.
Length = 659
Score = 301 bits (740), Expect = 2e-81
Identities = 158/385 (41%), Positives = 231/385 (60%), Gaps = 16/385 (4%)
Query: 75 VALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTLTGAVGWVPSNYVTPV-NSLEK 133
VALYD+ N L L+KG++ I+ + W A G G++PSNYVT +S+E
Sbjct: 220 VALYDYMPMNANDLQLRKGDEYFILEESNL-PWWRARDKNGQEGYIPSNYVTEAEDSIEM 278
Query: 134 HSWYHGPISRNAAEYLLSS-GINGSFLVRESESSPGQRSISLRY------EGRVYHYRIN 186
+ WY ++R+ AE LL G G F+VR+S S G+ ++S+ +G + HY +
Sbjct: 279 YEWYSKHMTRSQAEQLLKQEGKEGGFIVRDS-SKAGKYTVSVFAKSTGDPQGVIRHYVVC 337
Query: 187 EDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSK--PTVFPLAPPDHWE 244
+ Y+ + F T+ EL+++H GLI++L YP +++K P+ L WE
Sbjct: 338 STPQSQYYLAEKHLFSTIPELINYHQHNSAGLISRLKYPVSQQNKNAPSTAGLGYGS-WE 396
Query: 245 IDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASIMKEMRHP 304
ID D+ +LG GQ+G V W RG VA+K +K+ +M+ +F+EEA +M + H
Sbjct: 397 IDPKDLTFLKELGTGQFGVVKYGKW-RGQYDVAIKMIKEGSMSEDEFIEEAKVMMNLSHE 455
Query: 305 NLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIASGMSYLE 364
LVQL GVCT++ P +IITE+M+ G LL YLR L+ M + M YLE
Sbjct: 456 KLVQLYGVCTKQRPIFIITEYMANGCLLNYLREMRHRFQTQQ--LLEMCKDVCEAMEYLE 513
Query: 365 SRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEGLAYNT 424
S+ F+HRDLAARNCLV + +VKV+DFGL+R + DD YT+ G+KFP++W+ PE L Y+
Sbjct: 514 SKQFLHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDEYTSSVGSKFPVRWSPPEVLMYSK 573
Query: 425 FSTKSDVWAFGILLWEIATYGMSPY 449
FS+KSD+WAFG+L+WEI + G PY
Sbjct: 574 FSSKSDIWAFGVLMWEIYSLGKMPY 598
>BC109080-1|AAI09081.1| 659|Homo sapiens Bruton agammaglobulinemia
tyrosine kinase protein.
Length = 659
Score = 301 bits (740), Expect = 2e-81
Identities = 158/385 (41%), Positives = 231/385 (60%), Gaps = 16/385 (4%)
Query: 75 VALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTLTGAVGWVPSNYVTPV-NSLEK 133
VALYD+ N L L+KG++ I+ + W A G G++PSNYVT +S+E
Sbjct: 220 VALYDYMPMNANDLQLRKGDEYFILEESNL-PWWRARDKNGQEGYIPSNYVTEAEDSIEM 278
Query: 134 HSWYHGPISRNAAEYLLSS-GINGSFLVRESESSPGQRSISLRY------EGRVYHYRIN 186
+ WY ++R+ AE LL G G F+VR+S S G+ ++S+ +G + HY +
Sbjct: 279 YEWYSKHMTRSQAEQLLKQEGKEGGFIVRDS-SKAGKYTVSVFAKSTGDPQGVIRHYVVC 337
Query: 187 EDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSK--PTVFPLAPPDHWE 244
+ Y+ + F T+ EL+++H GLI++L YP +++K P+ L WE
Sbjct: 338 STPQSQYYLAEKHLFSTIPELINYHQHNSAGLISRLKYPVSQQNKNAPSTAGLGYGS-WE 396
Query: 245 IDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASIMKEMRHP 304
ID D+ +LG GQ+G V W RG VA+K +K+ +M+ +F+EEA +M + H
Sbjct: 397 IDPKDLTFLKELGTGQFGVVKYGKW-RGQYDVAIKMIKEGSMSEDEFIEEAKVMMNLSHE 455
Query: 305 NLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIASGMSYLE 364
LVQL GVCT++ P +IITE+M+ G LL YLR L+ M + M YLE
Sbjct: 456 KLVQLYGVCTKQRPIFIITEYMANGCLLNYLREMRHRFQTQQ--LLEMCKDVCEAMEYLE 513
Query: 365 SRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEGLAYNT 424
S+ F+HRDLAARNCLV + +VKV+DFGL+R + DD YT+ G+KFP++W+ PE L Y+
Sbjct: 514 SKQFLHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDEYTSSVGSKFPVRWSPPEVLMYSK 573
Query: 425 FSTKSDVWAFGILLWEIATYGMSPY 449
FS+KSD+WAFG+L+WEI + G PY
Sbjct: 574 FSSKSDIWAFGVLMWEIYSLGKMPY 598
>BC109079-1|AAI09080.1| 659|Homo sapiens Bruton agammaglobulinemia
tyrosine kinase protein.
Length = 659
Score = 301 bits (740), Expect = 2e-81
Identities = 158/385 (41%), Positives = 231/385 (60%), Gaps = 16/385 (4%)
Query: 75 VALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTLTGAVGWVPSNYVTPV-NSLEK 133
VALYD+ N L L+KG++ I+ + W A G G++PSNYVT +S+E
Sbjct: 220 VALYDYMPMNANDLQLRKGDEYFILEESNL-PWWRARDKNGQEGYIPSNYVTEAEDSIEM 278
Query: 134 HSWYHGPISRNAAEYLLSS-GINGSFLVRESESSPGQRSISLRY------EGRVYHYRIN 186
+ WY ++R+ AE LL G G F+VR+S S G+ ++S+ +G + HY +
Sbjct: 279 YEWYSKHMTRSQAEQLLKQEGKEGGFIVRDS-SKAGKYTVSVFAKSTGDPQGVIRHYVVC 337
Query: 187 EDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSK--PTVFPLAPPDHWE 244
+ Y+ + F T+ EL+++H GLI++L YP +++K P+ L WE
Sbjct: 338 STPQSQYYLAEKHLFSTIPELINYHQHNSAGLISRLKYPVSQQNKNAPSTAGLGYGS-WE 396
Query: 245 IDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASIMKEMRHP 304
ID D+ +LG GQ+G V W RG VA+K +K+ +M+ +F+EEA +M + H
Sbjct: 397 IDPKDLTFLKELGTGQFGVVKYGKW-RGQYDVAIKMIKEGSMSEDEFIEEAKVMMNLSHE 455
Query: 305 NLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIASGMSYLE 364
LVQL GVCT++ P +IITE+M+ G LL YLR L+ M + M YLE
Sbjct: 456 KLVQLYGVCTKQRPIFIITEYMANGCLLNYLREMRHRFQTQQ--LLEMCKDVCEAMEYLE 513
Query: 365 SRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEGLAYNT 424
S+ F+HRDLAARNCLV + +VKV+DFGL+R + DD YT+ G+KFP++W+ PE L Y+
Sbjct: 514 SKQFLHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDEYTSSVGSKFPVRWSPPEVLMYSK 573
Query: 425 FSTKSDVWAFGILLWEIATYGMSPY 449
FS+KSD+WAFG+L+WEI + G PY
Sbjct: 574 FSSKSDIWAFGVLMWEIYSLGKMPY 598
>AL035422-3|CAB55876.1| 659|Homo sapiens Bruton agammaglobulinemia
tyrosine kinase protein.
Length = 659
Score = 301 bits (740), Expect = 2e-81
Identities = 158/385 (41%), Positives = 231/385 (60%), Gaps = 16/385 (4%)
Query: 75 VALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTLTGAVGWVPSNYVTPV-NSLEK 133
VALYD+ N L L+KG++ I+ + W A G G++PSNYVT +S+E
Sbjct: 220 VALYDYMPMNANDLQLRKGDEYFILEESNL-PWWRARDKNGQEGYIPSNYVTEAEDSIEM 278
Query: 134 HSWYHGPISRNAAEYLLSS-GINGSFLVRESESSPGQRSISLRY------EGRVYHYRIN 186
+ WY ++R+ AE LL G G F+VR+S S G+ ++S+ +G + HY +
Sbjct: 279 YEWYSKHMTRSQAEQLLKQEGKEGGFIVRDS-SKAGKYTVSVFAKSTGDPQGVIRHYVVC 337
Query: 187 EDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSK--PTVFPLAPPDHWE 244
+ Y+ + F T+ EL+++H GLI++L YP +++K P+ L WE
Sbjct: 338 STPQSQYYLAEKHLFSTIPELINYHQHNSAGLISRLKYPVSQQNKNAPSTAGLGYGS-WE 396
Query: 245 IDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASIMKEMRHP 304
ID D+ +LG GQ+G V W RG VA+K +K+ +M+ +F+EEA +M + H
Sbjct: 397 IDPKDLTFLKELGTGQFGVVKYGKW-RGQYDVAIKMIKEGSMSEDEFIEEAKVMMNLSHE 455
Query: 305 NLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIASGMSYLE 364
LVQL GVCT++ P +IITE+M+ G LL YLR L+ M + M YLE
Sbjct: 456 KLVQLYGVCTKQRPIFIITEYMANGCLLNYLREMRHRFQTQQ--LLEMCKDVCEAMEYLE 513
Query: 365 SRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEGLAYNT 424
S+ F+HRDLAARNCLV + +VKV+DFGL+R + DD YT+ G+KFP++W+ PE L Y+
Sbjct: 514 SKQFLHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDEYTSSVGSKFPVRWSPPEVLMYSK 573
Query: 425 FSTKSDVWAFGILLWEIATYGMSPY 449
FS+KSD+WAFG+L+WEI + G PY
Sbjct: 574 FSSKSDIWAFGVLMWEIYSLGKMPY 598
>X05027-1|CAA28691.1| 507|Homo sapiens protein ( Human T
cell-specific mRNA (YT16) for PTK homologous protein PTK
= protein-tyrosine kinase. ).
Length = 507
Score = 298 bits (732), Expect = 2e-80
Identities = 175/406 (43%), Positives = 247/406 (60%), Gaps = 29/406 (7%)
Query: 73 LFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTLT-GAVGWVPSNYVTPVNSL 131
L +AL+ ++ + L +KGEQ+RI+ +SGEW +A +LT G G++P N+V NSL
Sbjct: 65 LVIALHSYEPSHDGDLGFEKGEQLRILE--QSGEWWKAQSLTTGQEGFIPFNFVAKANSL 122
Query: 132 EKHSWYHGPISRNAAE-YLLSSG-INGSFLVRESESSPGQRSISLR----YEGRVY-HYR 184
E W+ +SR AE LL+ G +GSFL+RESES+ G S+S+R +G V HY+
Sbjct: 123 EPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQNQGEVVKHYK 182
Query: 185 INEDADGKVYVTSESKFGTLAELVHHHS-VAGDGLITQLLYPAPKRSKPTVFPLAP--PD 241
I +G Y++ F L EL + +A DGL T+L P + P P D
Sbjct: 183 IRNLDNGGFYISPRITFPGLHELASAITPIASDGLCTRLSRPCQTQK-----PQKPWWED 237
Query: 242 HWEIDRTDIVMKHKLGGGQYGDVYEAAW--KRGNITVAVKTLKDDTMALKDFLEEASIMK 299
WE+ R + + +LG GQ+G W G VAVK+LK +M+ EA++MK
Sbjct: 238 EWEVPRETLKLVERLGAGQFG---RCGWGTTTGTTKVAVKSLKQGSMSAGRLPAEANLMK 294
Query: 300 EMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLR--AGARECVPGAVVLMYMATQIA 357
+++H LV+L V T+EP YIITE+M G+L+++L+ +G + + L+ MA QIA
Sbjct: 295 QLQHQRLVRLYAVVTQEP-IYIITEYMENGSLVDFLKTPSGIKLTINK---LLDMAAQIA 350
Query: 358 SGMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAP 417
GM+++E R++IHRDL A N LV + K+ADFGLARL+ D+ YTA GAKFPIKWTAP
Sbjct: 351 EGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAP 410
Query: 418 EGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
E + Y TF+ KSDVW+FGILL EI T+G PYPG+ +V LE+
Sbjct: 411 EAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLER 456
>U13433-1|AAC51347.1| 657|Homo sapiens Bruton's agammaglobulinemia
tyrosine kinase protein.
Length = 657
Score = 295 bits (725), Expect = 2e-79
Identities = 158/385 (41%), Positives = 230/385 (59%), Gaps = 18/385 (4%)
Query: 75 VALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTLTGAVGWVPSNYVTPV-NSLEK 133
VALYD+ N L L+KG++ I+ + W A G G++PSNYVT +S+E
Sbjct: 220 VALYDYMPMNANDLQLRKGDEYFILEESNL-PWWRARDKNGQEGYIPSNYVTEAEDSIEM 278
Query: 134 HSWYHGPISRNAAEYLLSS-GINGSFLVRESESSPGQRSISLRY------EGRVYHYRIN 186
WY ++R+ AE LL G G F+VR+S S G+ ++S+ +G + HY +
Sbjct: 279 --WYSKHMTRSQAEQLLKQEGKEGGFIVRDS-SKAGKYTVSVFAKSTGDPQGVIRHYVVC 335
Query: 187 EDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSK--PTVFPLAPPDHWE 244
+ Y+ + F T+ EL+++H GLI++L YP +++K P+ L WE
Sbjct: 336 STPQSQYYLAEKHLFSTIPELINYHQHNSAGLISRLKYPVSQQNKNAPSTAGLGYGS-WE 394
Query: 245 IDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASIMKEMRHP 304
ID D+ +LG GQ+G V W RG VA+K +K+ +M+ +F+EEA +M + H
Sbjct: 395 IDPKDLTFLKELGTGQFGVVKYGKW-RGQYDVAIKMIKEGSMSEDEFIEEAKVMMNLSHE 453
Query: 305 NLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIASGMSYLE 364
LVQL GVCT++ P +IITE+M+ G LL YLR L+ M + M YLE
Sbjct: 454 KLVQLYGVCTKQRPIFIITEYMANGCLLNYLREMRHRFQTQQ--LLEMCKDVCEAMEYLE 511
Query: 365 SRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEGLAYNT 424
S+ F+HRDLAARNCLV + +VKV+DFGL+R + DD YT+ G+KFP++W+ PE L Y+
Sbjct: 512 SKQFLHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDEYTSSVGSKFPVRWSPPEVLMYSK 571
Query: 425 FSTKSDVWAFGILLWEIATYGMSPY 449
FS+KSD+WAFG+L+WEI + G PY
Sbjct: 572 FSSKSDIWAFGVLMWEIYSLGKMPY 596
>L27071-1|AAA74557.1| 527|Homo sapiens tyrosine kinase protein.
Length = 527
Score = 289 bits (708), Expect = 2e-77
Identities = 155/386 (40%), Positives = 224/386 (58%), Gaps = 19/386 (4%)
Query: 76 ALYDFQAGGENQLTLKKGEQVRIMS-YNKSGEWCEAHTLTGAVGWVPSNYVTP--VNSLE 132
ALYDF L L++ E+ I+ YN W +A G G +PSNYVT + +LE
Sbjct: 89 ALYDFLPREPCNLALRRAEEYLILEKYNP--HWWKARDRLGNEGLIPSNYVTENKITNLE 146
Query: 133 KHSWYHGPISRNAAEYLL-SSGINGSFLVRESESSPGQRSISL------RYEGRVYHYRI 185
+ WYH I+RN AE+LL G+F+VR+S G +IS+ E + HY+I
Sbjct: 147 IYEWYHRNITRNQAEHLLRQESKEGAFIVRDSRHL-GSYTISVFMGARRSTEAAIKHYQI 205
Query: 186 NEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSK--PTVFPLAPPDHW 243
++ G+ YV F ++ EL+ +H GL+T+L YP P + + W
Sbjct: 206 KKNDSGQWYVAERHAFQSIPELIWYHQHNAAGLMTRLRYPVGLMGSCLPATAGFSY-EKW 264
Query: 244 EIDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASIMKEMRH 303
EID +++ ++G GQ+G V+ W R +I VA+K + + +M+ +DF+EEA +M ++ H
Sbjct: 265 EIDPSELAFIKEIGSGQFGVVHLGEW-RSHIQVAIKAINEGSMSEEDFIEEAKVMMKLSH 323
Query: 304 PNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIASGMSYL 363
LVQL GVC + P YI+TEFM G LL YLR + +L+ + I GM YL
Sbjct: 324 SKLVQLYGVCIQRKPLYIVTEFMENGCLLNYLRENKGKL--RKEMLLSVCQDICEGMEYL 381
Query: 364 ESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEGLAYN 423
E +IHRDLAARNCLV +VK++DFG+ R + DD Y + GAKFPIKW+ PE +N
Sbjct: 382 ERNGYIHRDLAARNCLVSSTCIVKISDFGMTRYVLDDEYVSSFGAKFPIKWSPPEVFLFN 441
Query: 424 TFSTKSDVWAFGILLWEIATYGMSPY 449
+S+KSDVW+FG+L+WE+ T G P+
Sbjct: 442 KYSSKSDVWSFGVLMWEVFTEGKMPF 467
>U34379-1|AAB60412.1| 527|Homo sapiens tyrosine kinase protein.
Length = 527
Score = 287 bits (705), Expect = 4e-77
Identities = 155/386 (40%), Positives = 223/386 (57%), Gaps = 19/386 (4%)
Query: 76 ALYDFQAGGENQLTLKKGEQVRIMS-YNKSGEWCEAHTLTGAVGWVPSNYVTP--VNSLE 132
ALYDF L L++ E+ I+ YN W +A G G +PSNYVT + +LE
Sbjct: 89 ALYDFLPREPCNLALRRAEEYLILEKYNP--HWWKARDRLGNEGLIPSNYVTENKITNLE 146
Query: 133 KHSWYHGPISRNAAEYLL-SSGINGSFLVRESESSPGQRSISL------RYEGRVYHYRI 185
+ WYH I+RN AE+LL G+F+VR+S G +IS+ E + HY+I
Sbjct: 147 IYEWYHRNITRNQAEHLLRQESKEGAFIVRDSRHL-GSYTISVFMGARRSTEAAIKHYQI 205
Query: 186 NEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSK--PTVFPLAPPDHW 243
++ G+ YV F ++ EL+ +H GL+T+L YP P + + W
Sbjct: 206 KKNDSGQWYVAERHAFQSIPELIWYHQHNAAGLMTRLRYPVGLMGSCLPATAGFSY-EKW 264
Query: 244 EIDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASIMKEMRH 303
EID +++ +G GQ+G V+ W R +I VA+K + + +M+ +DF+EEA +M ++ H
Sbjct: 265 EIDPSELAFIKXIGSGQFGVVHLGEW-RSHIQVAIKAINEGSMSEEDFIEEAKVMMKLSH 323
Query: 304 PNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIASGMSYL 363
LVQL GVC + P YI+TEFM G LL YLR + +L+ + I GM YL
Sbjct: 324 SKLVQLYGVCIQRKPLYIVTEFMENGCLLNYLRENKGKL--RKEMLLSVCQXICEGMEYL 381
Query: 364 ESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEGLAYN 423
E +IHRDLAARNCLV +VK++DFG+ R + DD Y + GAKFPIKW+ PE +N
Sbjct: 382 ERNGYIHRDLAARNCLVSSTCIVKISDFGMTRYVLDDEYVSSFGAKFPIKWSPPEVFLFN 441
Query: 424 TFSTKSDVWAFGILLWEIATYGMSPY 449
+S+KSDVW+FG+L+WE+ T G P+
Sbjct: 442 KYSSKSDVWSFGVLMWEVFTEGKMPF 467
>L10717-1|AAA36748.1| 620|Homo sapiens tyrosine kinase protein.
Length = 620
Score = 287 bits (703), Expect = 8e-77
Identities = 150/395 (37%), Positives = 233/395 (58%), Gaps = 18/395 (4%)
Query: 68 EDDPQLFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTLTGAVGWVPSNYVTP 127
E + + +ALYD+Q +L L++ E+ ++ ++ W G G+VPS+Y+
Sbjct: 170 EPEETVVIALYDYQTNDPQELALRRNEEYCLLDSSEI-HWWRVQDRNGHEGYVPSSYLVE 228
Query: 128 V--NSLEKHSWYHGPISRNAAE-YLLSSGINGSFLVRESESSPGQRSISLRYEGRVY--- 181
N+LE + WY+ ISR+ AE LL +G G+F+VR+S ++ G ++S+ + V
Sbjct: 229 KSPNNLETYEWYNKSISRDKAEKLLLDTGKEGAFMVRDSRTA-GTYTVSVFTKAVVSENN 287
Query: 182 ----HYRINEDADG--KVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAP-KRSKPTV 234
HY I E D + YV + F ++ L+++H G GL+T+L YP R K V
Sbjct: 288 PCIKHYHIKETNDNPKRYYVAEKYVFDSIPLLINYHQHNGGGLVTRLRYPVCFGRQKAPV 347
Query: 235 FPLAPPDHWEIDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEE 294
W ID +++ ++G GQ+G V+ W + VA+KT+++ M+ +DF+EE
Sbjct: 348 TAGLRYGKWVIDPSELTFVQEIGSGQFGLVHLGYWLNKD-KVAIKTIREGAMSEEDFIEE 406
Query: 295 ASIMKEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMAT 354
A +M ++ HP LVQL GVC + P ++ EFM G L +YLR + + A L+ M
Sbjct: 407 AEVMMKLSHPKLVQLYGVCLEQAPICLVFEFMEHGCLSDYLRT--QRGLFAAETLLGMCL 464
Query: 355 QIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKW 414
+ GM+YLE IHRDLAARNCLVGEN ++KV+DFG+ R + DD YT+ G KFP+KW
Sbjct: 465 DVCEGMAYLEEACVIHRDLAARNCLVGENQVIKVSDFGMTRFVLDDQYTSSTGTKFPVKW 524
Query: 415 TAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPY 449
+PE +++ +S+KSDVW+FG+L+WE+ + G PY
Sbjct: 525 ASPEVFSFSRYSSKSDVWSFGVLMWEVFSEGKIPY 559
>D13720-1|BAA02873.1| 620|Homo sapiens ITK protein.
Length = 620
Score = 287 bits (703), Expect = 8e-77
Identities = 150/395 (37%), Positives = 233/395 (58%), Gaps = 18/395 (4%)
Query: 68 EDDPQLFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTLTGAVGWVPSNYVTP 127
E + + +ALYD+Q +L L++ E+ ++ ++ W G G+VPS+Y+
Sbjct: 170 EPEETVVIALYDYQTNDPQELALRRNEEYCLLDSSEI-HWWRVQDRNGHEGYVPSSYLVE 228
Query: 128 V--NSLEKHSWYHGPISRNAAE-YLLSSGINGSFLVRESESSPGQRSISLRYEGRVY--- 181
N+LE + WY+ ISR+ AE LL +G G+F+VR+S ++ G ++S+ + V
Sbjct: 229 KSPNNLETYEWYNKSISRDKAEKLLLDTGKEGAFMVRDSRTA-GTYTVSVFTKAVVSENN 287
Query: 182 ----HYRINEDADG--KVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAP-KRSKPTV 234
HY I E D + YV + F ++ L+++H G GL+T+L YP R K V
Sbjct: 288 PCIKHYHIKETNDNPKRYYVAEKYVFDSIPLLINYHQHNGGGLVTRLRYPVCFGRQKAPV 347
Query: 235 FPLAPPDHWEIDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEE 294
W ID +++ ++G GQ+G V+ W + VA+KT+++ M+ +DF+EE
Sbjct: 348 TAGLRYGKWVIDPSELTFVQEIGSGQFGLVHLGYWLNKD-KVAIKTIREGAMSEEDFIEE 406
Query: 295 ASIMKEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMAT 354
A +M ++ HP LVQL GVC + P ++ EFM G L +YLR + + A L+ M
Sbjct: 407 AEVMMKLSHPKLVQLYGVCLEQAPICLVFEFMEHGCLSDYLRT--QRGLFAAETLLGMCL 464
Query: 355 QIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKW 414
+ GM+YLE IHRDLAARNCLVGEN ++KV+DFG+ R + DD YT+ G KFP+KW
Sbjct: 465 DVCEGMAYLEEACVIHRDLAARNCLVGENQVIKVSDFGMTRFVLDDQYTSSTGTKFPVKW 524
Query: 415 TAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPY 449
+PE +++ +S+KSDVW+FG+L+WE+ + G PY
Sbjct: 525 ASPEVFSFSRYSSKSDVWSFGVLMWEVFSEGKIPY 559
>BC109078-1|AAI09079.1| 620|Homo sapiens IL2-inducible T-cell
kinase protein.
Length = 620
Score = 287 bits (703), Expect = 8e-77
Identities = 150/395 (37%), Positives = 233/395 (58%), Gaps = 18/395 (4%)
Query: 68 EDDPQLFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTLTGAVGWVPSNYVTP 127
E + + +ALYD+Q +L L++ E+ ++ ++ W G G+VPS+Y+
Sbjct: 170 EPEETVVIALYDYQTNDPQELALRRNEEYCLLDSSEI-HWWRVQDRNGHEGYVPSSYLVE 228
Query: 128 V--NSLEKHSWYHGPISRNAAE-YLLSSGINGSFLVRESESSPGQRSISLRYEGRVY--- 181
N+LE + WY+ ISR+ AE LL +G G+F+VR+S ++ G ++S+ + V
Sbjct: 229 KSPNNLETYEWYNKSISRDKAEKLLLDTGKEGAFMVRDSRTA-GTYTVSVFTKAVVSENN 287
Query: 182 ----HYRINEDADG--KVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAP-KRSKPTV 234
HY I E D + YV + F ++ L+++H G GL+T+L YP R K V
Sbjct: 288 PCIKHYHIKETNDNPKRYYVAEKYVFDSIPLLINYHQHNGGGLVTRLRYPVCFGRQKAPV 347
Query: 235 FPLAPPDHWEIDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEE 294
W ID +++ ++G GQ+G V+ W + VA+KT+++ M+ +DF+EE
Sbjct: 348 TAGLRYGKWVIDPSELTFVQEIGSGQFGLVHLGYWLNKD-KVAIKTIREGAMSEEDFIEE 406
Query: 295 ASIMKEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMAT 354
A +M ++ HP LVQL GVC + P ++ EFM G L +YLR + + A L+ M
Sbjct: 407 AEVMMKLSHPKLVQLYGVCLEQAPICLVFEFMEHGCLSDYLRT--QRGLFAAETLLGMCL 464
Query: 355 QIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKW 414
+ GM+YLE IHRDLAARNCLVGEN ++KV+DFG+ R + DD YT+ G KFP+KW
Sbjct: 465 DVCEGMAYLEEACVIHRDLAARNCLVGENQVIKVSDFGMTRFVLDDQYTSSTGTKFPVKW 524
Query: 415 TAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPY 449
+PE +++ +S+KSDVW+FG+L+WE+ + G PY
Sbjct: 525 ASPEVFSFSRYSSKSDVWSFGVLMWEVFSEGKIPY 559
>BC109077-1|AAI09078.1| 620|Homo sapiens IL2-inducible T-cell
kinase protein.
Length = 620
Score = 287 bits (703), Expect = 8e-77
Identities = 150/395 (37%), Positives = 233/395 (58%), Gaps = 18/395 (4%)
Query: 68 EDDPQLFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTLTGAVGWVPSNYVTP 127
E + + +ALYD+Q +L L++ E+ ++ ++ W G G+VPS+Y+
Sbjct: 170 EPEETVVIALYDYQTNDPQELALRRNEEYCLLDSSEI-HWWRVQDRNGHEGYVPSSYLVE 228
Query: 128 V--NSLEKHSWYHGPISRNAAE-YLLSSGINGSFLVRESESSPGQRSISLRYEGRVY--- 181
N+LE + WY+ ISR+ AE LL +G G+F+VR+S ++ G ++S+ + V
Sbjct: 229 KSPNNLETYEWYNKSISRDKAEKLLLDTGKEGAFMVRDSRTA-GTYTVSVFTKAVVSENN 287
Query: 182 ----HYRINEDADG--KVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAP-KRSKPTV 234
HY I E D + YV + F ++ L+++H G GL+T+L YP R K V
Sbjct: 288 PCIKHYHIKETNDNPKRYYVAEKYVFDSIPLLINYHQHNGGGLVTRLRYPVCFGRQKAPV 347
Query: 235 FPLAPPDHWEIDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEE 294
W ID +++ ++G GQ+G V+ W + VA+KT+++ M+ +DF+EE
Sbjct: 348 TAGLRYGKWVIDPSELTFVQEIGSGQFGLVHLGYWLNKD-KVAIKTIREGAMSEEDFIEE 406
Query: 295 ASIMKEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMAT 354
A +M ++ HP LVQL GVC + P ++ EFM G L +YLR + + A L+ M
Sbjct: 407 AEVMMKLSHPKLVQLYGVCLEQAPICLVFEFMEHGCLSDYLRT--QRGLFAAETLLGMCL 464
Query: 355 QIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKW 414
+ GM+YLE IHRDLAARNCLVGEN ++KV+DFG+ R + DD YT+ G KFP+KW
Sbjct: 465 DVCEGMAYLEEACVIHRDLAARNCLVGENQVIKVSDFGMTRFVLDDQYTSSTGTKFPVKW 524
Query: 415 TAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPY 449
+PE +++ +S+KSDVW+FG+L+WE+ + G PY
Sbjct: 525 ASPEVFSFSRYSSKSDVWSFGVLMWEVFSEGKIPY 559
>Z97989-6|CAI22299.1| 485|Homo sapiens FYN oncogene related to SRC,
FGR, YES protein.
Length = 485
Score = 285 bits (699), Expect = 2e-76
Identities = 154/335 (45%), Positives = 215/335 (64%), Gaps = 12/335 (3%)
Query: 136 WYHGPISRNAAE-YLLSSGI-NGSFLVRESESSPGQRSISLR----YEG-RVYHYRINED 188
WY G + R AE LLS G G+FL+RESE++ G S+S+R +G V HY+I +
Sbjct: 100 WYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGDHVKHYKIRKL 159
Query: 189 ADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKPTVFPLAPPDHWEIDRT 248
+G Y+T+ ++F TL +LV H+S DGL L A + P LA D WE+ R
Sbjct: 160 DNGGYYITTRAQFETLQQLVQHYSEKADGLCFNLTVIASSCT-PQTSGLAK-DAWEVARR 217
Query: 249 DIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASIMKEMRHPNLVQ 308
+ ++ KLG G + +V+ W GN VA+KTLK TM+ + FLEEA IMK+++H LVQ
Sbjct: 218 SLCLEKKLGQGCFAEVWLGTWN-GNTKVAIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQ 276
Query: 309 LLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIASGMSYLESRSF 368
L V + EP YI+TE+M++G+LL++L+ G + L+ MA Q+A+GM+Y+E ++
Sbjct: 277 LYAVVSEEP-IYIVTEYMNKGSLLDFLKDGEGRALK-LPNLVDMAAQVAAGMAYIERMNY 334
Query: 369 IHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEGLAYNTFSTK 428
IHRDL + N LVG + K+ADFGLARL+ D+ YTA GAKFPIKWTAPE Y F+ K
Sbjct: 335 IHRDLRSANILVGNGLICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIK 394
Query: 429 SDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
SDVW+FGILL E+ T G PYPG++ +V +E+
Sbjct: 395 SDVWSFGILLTELVTKGRVPYPGMNNREVLEQVER 429
>AL121829-14|CAC15526.1| 488|Homo sapiens protein ( Human DNA
sequence from clone RP4-697K14 on chromosome 20. ).
Length = 488
Score = 285 bits (698), Expect = 3e-76
Identities = 156/388 (40%), Positives = 225/388 (57%), Gaps = 16/388 (4%)
Query: 71 PQLFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTLTG--AVGWVPSNYVTPV 128
PQLF+ALYDF A +L++++G+ R+ + + G + A L+G + G VP +V
Sbjct: 53 PQLFLALYDFTARCGGELSVRRGD--RLCALEEGGGYIFARRLSGQPSAGLVPITHVAKA 110
Query: 129 N--SLEKHSWYHGPISRNAAEYLLSSGIN--GSFLVRESESSPGQRSISLRYEGRVYHYR 184
+ +L WY +SR A+ LL S N G+FL+R SESS G S+S+R + +V HYR
Sbjct: 111 SPETLSDQPWYFSGVSRTQAQQLLLSPPNEPGAFLIRPSESSLGGYSLSVRAQAKVCHYR 170
Query: 185 INEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKPTVFPLAPPDHWE 244
++ ADG +Y+ F L EL+ ++ + LL P + P D WE
Sbjct: 171 VSMAADGSLYLQKGRLFPGLEELLTYYKANWKLIQNPLLQPCMPQKAPR------QDVWE 224
Query: 245 IDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASIMKEMRHP 304
++ + KLG G +G+V+E W G++ VA+K +K M L D +E +K +RH
Sbjct: 225 RPHSEFALGRKLGEGYFGEVWEGLWL-GSLPVAIKVIKSANMKLTDLAKEIQTLKGLRHE 283
Query: 305 NLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIASGMSYLE 364
L++L VC+ P YI+TE M +GNL +L + +L + A Q+A GMSYLE
Sbjct: 284 RLIRLHAVCSGGEPVYIVTELMRKGNLQAFLGTPEGRALRLPPLLGF-ACQVAEGMSYLE 342
Query: 365 SRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEGLAYNT 424
+ +HRDLAARN LV + KVADFGLARL++DD Y+ + +K P+KWTAPE Y
Sbjct: 343 EQRVVHRDLAARNVLVDDGLACKVADFGLARLLKDDIYSPSSSSKIPVKWTAPEAANYRV 402
Query: 425 FSTKSDVWAFGILLWEIATYGMSPYPGV 452
FS KSDVW+FG+LL E+ TYG PY G+
Sbjct: 403 FSQKSDVWSFGVLLHEVFTYGQCPYEGM 430
>X74765-1|CAB58562.1| 450|Homo sapiens protein tyrosine kinase
protein.
Length = 450
Score = 284 bits (697), Expect = 4e-76
Identities = 159/396 (40%), Positives = 229/396 (57%), Gaps = 16/396 (4%)
Query: 75 VALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTLTGAVGWVPSNYVTPVNSLEKH 134
+A Y+F E L KG+ + I++ K W +A G G +P+NYV ++
Sbjct: 15 IAKYNFHGTAEQDLPFCKGDVLTIVAVTKDPNWYKAKNKVGREGIIPANYVQKREGVKAG 74
Query: 135 S------WYHGPISRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINED 188
+ W+HG I+R AE LL G FLVRES + PG ++ + +G+V HYRI
Sbjct: 75 TKLSLMPWFHGKITREQAERLLYPPETGLFLVRESTNYPGDYTLCVSCDGKVEHYRIMYH 134
Query: 189 ADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKPTVFPLAPPDHWEIDRT 248
A K+ + E F L +LV H++ DGL T+L+ P W ++
Sbjct: 135 AS-KLSIDEEVYFENLMQLVEHYTSDADGLCTRLIKPKVMEGTVAAQDEFYRSGWALNMK 193
Query: 249 DIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASIMKEMRHPNLVQ 308
++ + +G G++GDV + RGN VAVK +K+D A + FL EAS+M ++RH NLVQ
Sbjct: 194 ELKLLQTIGKGEFGDVMLGDY-RGN-KVAVKCIKNDATA-QAFLAEASVMTQLRHSNLVQ 250
Query: 309 LLGVCTREPP-FYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIASGMSYLESRS 367
LLGV E YI+TE+M++G+L++YLR+ R + G +L + + + M YLE +
Sbjct: 251 LLGVIVEEKGGLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKF-SLDVCEAMEYLEGNN 309
Query: 368 FIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEGLAYNTFST 427
F+HRDLAARN LV E+++ KV+DFGL + + + T G K P+KWTAPE L FST
Sbjct: 310 FVHRDLAARNVLVSEDNVAKVSDFGLTK---EASSTQDTG-KLPVKWTAPEALREKKFST 365
Query: 428 KSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
KSDVW+FGILLWEI ++G PYP + L DV +EK
Sbjct: 366 KSDVWSFGILLWEIYSFGRVPYPRIPLKDVVPRVEK 401
>X60114-1|CAA42713.1| 450|Homo sapiens put. cytoplasmic tyrosine
kinase protein.
Length = 450
Score = 284 bits (697), Expect = 4e-76
Identities = 159/396 (40%), Positives = 229/396 (57%), Gaps = 16/396 (4%)
Query: 75 VALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTLTGAVGWVPSNYVTPVNSLEKH 134
+A Y+F E L KG+ + I++ K W +A G G +P+NYV ++
Sbjct: 15 IAKYNFHGTAEQDLPFCKGDVLTIVAVTKDPNWYKAKNKVGREGIIPANYVQKREGVKAG 74
Query: 135 S------WYHGPISRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINED 188
+ W+HG I+R AE LL G FLVRES + PG ++ + +G+V HYRI
Sbjct: 75 TKLSLMPWFHGKITREQAERLLYPPETGLFLVRESTNYPGDYTLCVSCDGKVEHYRIMYH 134
Query: 189 ADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKPTVFPLAPPDHWEIDRT 248
A K+ + E F L +LV H++ DGL T+L+ P W ++
Sbjct: 135 AS-KLSIDEEVYFENLMQLVEHYTSDADGLCTRLIKPKVMEGTVAAQDEFYRSGWALNMK 193
Query: 249 DIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASIMKEMRHPNLVQ 308
++ + +G G++GDV + RGN VAVK +K+D A + FL EAS+M ++RH NLVQ
Sbjct: 194 ELKLLQTIGKGEFGDVMLGDY-RGN-KVAVKCIKNDATA-QAFLAEASVMTQLRHSNLVQ 250
Query: 309 LLGVCTREPP-FYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIASGMSYLESRS 367
LLGV E YI+TE+M++G+L++YLR+ R + G +L + + + M YLE +
Sbjct: 251 LLGVIVEEKGGLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKF-SLDVCEAMEYLEGNN 309
Query: 368 FIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEGLAYNTFST 427
F+HRDLAARN LV E+++ KV+DFGL + + + T G K P+KWTAPE L FST
Sbjct: 310 FVHRDLAARNVLVSEDNVAKVSDFGLTK---EASSTQDTG-KLPVKWTAPEALREKKFST 365
Query: 428 KSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
KSDVW+FGILLWEI ++G PYP + L DV +EK
Sbjct: 366 KSDVWSFGILLWEIYSFGRVPYPRIPLKDVVPRVEK 401
>X59932-1|CAA42556.1| 450|Homo sapiens c-src-kinase protein.
Length = 450
Score = 284 bits (697), Expect = 4e-76
Identities = 159/396 (40%), Positives = 229/396 (57%), Gaps = 16/396 (4%)
Query: 75 VALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTLTGAVGWVPSNYVTPVNSLEKH 134
+A Y+F E L KG+ + I++ K W +A G G +P+NYV ++
Sbjct: 15 IAKYNFHGTAEQDLPFCKGDVLTIVAVTKDPNWYKAKNKVGREGIIPANYVQKREGVKAG 74
Query: 135 S------WYHGPISRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINED 188
+ W+HG I+R AE LL G FLVRES + PG ++ + +G+V HYRI
Sbjct: 75 TKLSLMPWFHGKITREQAERLLYPPETGLFLVRESTNYPGDYTLCVSCDGKVEHYRIMYH 134
Query: 189 ADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKPTVFPLAPPDHWEIDRT 248
A K+ + E F L +LV H++ DGL T+L+ P W ++
Sbjct: 135 AS-KLSIDEEVYFENLMQLVEHYTSDADGLCTRLIKPKVMEGTVAAQDEFYRSGWALNMK 193
Query: 249 DIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASIMKEMRHPNLVQ 308
++ + +G G++GDV + RGN VAVK +K+D A + FL EAS+M ++RH NLVQ
Sbjct: 194 ELKLLQTIGKGEFGDVMLGDY-RGN-KVAVKCIKNDATA-QAFLAEASVMTQLRHSNLVQ 250
Query: 309 LLGVCTREPP-FYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIASGMSYLESRS 367
LLGV E YI+TE+M++G+L++YLR+ R + G +L + + + M YLE +
Sbjct: 251 LLGVIVEEKGGLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKF-SLDVCEAMEYLEGNN 309
Query: 368 FIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEGLAYNTFST 427
F+HRDLAARN LV E+++ KV+DFGL + + + T G K P+KWTAPE L FST
Sbjct: 310 FVHRDLAARNVLVSEDNVAKVSDFGLTK---EASSTQDTG-KLPVKWTAPEALREKKFST 365
Query: 428 KSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
KSDVW+FGILLWEI ++G PYP + L DV +EK
Sbjct: 366 KSDVWSFGILLWEIYSFGRVPYPRIPLKDVVPRVEK 401
>S65186-1|AAB28072.2| 620|Homo sapiens EMT protein.
Length = 620
Score = 284 bits (697), Expect = 4e-76
Identities = 150/395 (37%), Positives = 232/395 (58%), Gaps = 18/395 (4%)
Query: 68 EDDPQLFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTLTGAVGWVPSNYVTP 127
E + + +ALYD+Q +L L++ E+ ++ ++ W G G+VPS+Y+
Sbjct: 170 EPEETVVIALYDYQTNDPQELALRRNEEYCLLDSSEI-HWWRVQDRNGHEGYVPSSYLVE 228
Query: 128 V--NSLEKHSWYHGPISRNAAE-YLLSSGINGSFLVRESESSPGQRSISLRYEGRVY--- 181
N+LE + WY+ ISR+ AE LL +G G+F+VR+S ++ G ++S+ + V
Sbjct: 229 KSPNNLETYEWYNKSISRDKAEKLLLDTGKEGAFMVRDSRTA-GTYTVSVFTKAVVSENN 287
Query: 182 ----HYRINEDADG--KVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAP-KRSKPTV 234
HY I E D + YV + F ++ L+++H G GL T+L YP R K V
Sbjct: 288 PCIKHYHIKETNDNPKRYYVAEKYVFDSIPLLINYHQHNGGGLWTRLRYPVCFGRQKAPV 347
Query: 235 FPLAPPDHWEIDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEE 294
W ID +++ ++G GQ+G V+ W + VA+KT+++ M+ +DF+EE
Sbjct: 348 TAGLRYGKWVIDPSELTFVQEIGSGQFGLVHLGYWLNKD-KVAIKTIREGAMSEEDFIEE 406
Query: 295 ASIMKEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMAT 354
A +M ++ HP LVQL GVC + P ++ EFM G L +YLR + + A L+ M
Sbjct: 407 AEVMMKLSHPKLVQLYGVCLEQAPICLVFEFMEHGCLSDYLRT--QRGLFAAETLLGMCL 464
Query: 355 QIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKW 414
+ GM+YLE IHRDLAARNCLVGEN ++KV+DFG+ R + DD YT+ G KFP+KW
Sbjct: 465 DVCEGMAYLEEACVIHRDLAARNCLVGENQVIKVSDFGMTRFVLDDQYTSSTGTKFPVKW 524
Query: 415 TAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPY 449
+PE +++ +S+KSDVW+FG+L+WE+ + G PY
Sbjct: 525 ASPEVFSFSRYSSKSDVWSFGVLMWEVFSEGKIPY 559
>DQ075211-1|AAY57329.1| 450|Homo sapiens c-src tyrosine kinase
protein.
Length = 450
Score = 284 bits (697), Expect = 4e-76
Identities = 159/396 (40%), Positives = 229/396 (57%), Gaps = 16/396 (4%)
Query: 75 VALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTLTGAVGWVPSNYVTPVNSLEKH 134
+A Y+F E L KG+ + I++ K W +A G G +P+NYV ++
Sbjct: 15 IAKYNFHGTAEQDLPFCKGDVLTIVAVTKDPNWYKAKNKVGREGIIPANYVQKREGVKAG 74
Query: 135 S------WYHGPISRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINED 188
+ W+HG I+R AE LL G FLVRES + PG ++ + +G+V HYRI
Sbjct: 75 TKLSLMPWFHGKITREQAERLLYPPETGLFLVRESTNYPGDYTLCVSCDGKVEHYRIMYH 134
Query: 189 ADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKPTVFPLAPPDHWEIDRT 248
A K+ + E F L +LV H++ DGL T+L+ P W ++
Sbjct: 135 AS-KLSIDEEVYFENLMQLVEHYTSDADGLCTRLIKPKVMEGTVAAQDEFYRSGWALNMK 193
Query: 249 DIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASIMKEMRHPNLVQ 308
++ + +G G++GDV + RGN VAVK +K+D A + FL EAS+M ++RH NLVQ
Sbjct: 194 ELKLLQTIGKGEFGDVMLGDY-RGN-KVAVKCIKNDATA-QAFLAEASVMTQLRHSNLVQ 250
Query: 309 LLGVCTREPP-FYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIASGMSYLESRS 367
LLGV E YI+TE+M++G+L++YLR+ R + G +L + + + M YLE +
Sbjct: 251 LLGVIVEEKGGLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKF-SLDVCEAMEYLEGNN 309
Query: 368 FIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEGLAYNTFST 427
F+HRDLAARN LV E+++ KV+DFGL + + + T G K P+KWTAPE L FST
Sbjct: 310 FVHRDLAARNVLVSEDNVAKVSDFGLTK---EASSTQDTG-KLPVKWTAPEALREKKFST 365
Query: 428 KSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
KSDVW+FGILLWEI ++G PYP + L DV +EK
Sbjct: 366 KSDVWSFGILLWEIYSFGRVPYPRIPLKDVVPRVEK 401
>CR541960-1|CAG46758.1| 450|Homo sapiens CSK protein.
Length = 450
Score = 284 bits (697), Expect = 4e-76
Identities = 159/396 (40%), Positives = 229/396 (57%), Gaps = 16/396 (4%)
Query: 75 VALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTLTGAVGWVPSNYVTPVNSLEKH 134
+A Y+F E L KG+ + I++ K W +A G G +P+NYV ++
Sbjct: 15 IAKYNFHGTAEQDLPFCKGDVLTIVAVTKDPNWYKAKNKVGREGIIPANYVQKREGVKAG 74
Query: 135 S------WYHGPISRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINED 188
+ W+HG I+R AE LL G FLVRES + PG ++ + +G+V HYRI
Sbjct: 75 TKLSLMPWFHGKITREQAERLLYPPETGLFLVRESTNYPGDYTLCVSCDGKVEHYRIMYH 134
Query: 189 ADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKPTVFPLAPPDHWEIDRT 248
A K+ + E F L +LV H++ DGL T+L+ P W ++
Sbjct: 135 AS-KLSIDEEVYFENLMQLVEHYTSDADGLCTRLIKPKVMEGTVAAQDEFYRSGWALNMK 193
Query: 249 DIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASIMKEMRHPNLVQ 308
++ + +G G++GDV + RGN VAVK +K+D A + FL EAS+M ++RH NLVQ
Sbjct: 194 ELKLLQTIGKGEFGDVMLGDY-RGN-KVAVKCIKNDATA-QAFLAEASVMTQLRHSNLVQ 250
Query: 309 LLGVCTREPP-FYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIASGMSYLESRS 367
LLGV E YI+TE+M++G+L++YLR+ R + G +L + + + M YLE +
Sbjct: 251 LLGVIVEEKGGLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKF-SLDVCEAMEYLEGNN 309
Query: 368 FIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEGLAYNTFST 427
F+HRDLAARN LV E+++ KV+DFGL + + + T G K P+KWTAPE L FST
Sbjct: 310 FVHRDLAARNVLVSEDNVAKVSDFGLTK---EASSTQDTG-KLPVKWTAPEALREKKFST 365
Query: 428 KSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
KSDVW+FGILLWEI ++G PYP + L DV +EK
Sbjct: 366 KSDVWSFGILLWEIYSFGRVPYPRIPLKDVVPRVEK 401
>BC106073-1|AAI06074.1| 450|Homo sapiens c-src tyrosine kinase
protein.
Length = 450
Score = 284 bits (697), Expect = 4e-76
Identities = 159/396 (40%), Positives = 229/396 (57%), Gaps = 16/396 (4%)
Query: 75 VALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTLTGAVGWVPSNYVTPVNSLEKH 134
+A Y+F E L KG+ + I++ K W +A G G +P+NYV ++
Sbjct: 15 IAKYNFHGTAEQDLPFCKGDVLTIVAVTKDPNWYKAKNKVGREGIIPANYVQKREGVKAG 74
Query: 135 S------WYHGPISRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINED 188
+ W+HG I+R AE LL G FLVRES + PG ++ + +G+V HYRI
Sbjct: 75 TKLSLMPWFHGKITREQAERLLYPPETGLFLVRESTNYPGDYTLCVSCDGKVEHYRIMYH 134
Query: 189 ADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKPTVFPLAPPDHWEIDRT 248
A K+ + E F L +LV H++ DGL T+L+ P W ++
Sbjct: 135 AS-KLSIDEEVYFENLMQLVEHYTSDADGLCTRLIKPKVMEGTVAAQDEFYRSGWALNMK 193
Query: 249 DIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASIMKEMRHPNLVQ 308
++ + +G G++GDV + RGN VAVK +K+D A + FL EAS+M ++RH NLVQ
Sbjct: 194 ELKLLQTIGKGEFGDVMLGDY-RGN-KVAVKCIKNDATA-QAFLAEASVMTQLRHSNLVQ 250
Query: 309 LLGVCTREPP-FYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIASGMSYLESRS 367
LLGV E YI+TE+M++G+L++YLR+ R + G +L + + + M YLE +
Sbjct: 251 LLGVIVEEKGGLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKF-SLDVCEAMEYLEGNN 309
Query: 368 FIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEGLAYNTFST 427
F+HRDLAARN LV E+++ KV+DFGL + + + T G K P+KWTAPE L FST
Sbjct: 310 FVHRDLAARNVLVSEDNVAKVSDFGLTK---EASSTQDTG-KLPVKWTAPEALREKKFST 365
Query: 428 KSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
KSDVW+FGILLWEI ++G PYP + L DV +EK
Sbjct: 366 KSDVWSFGILLWEIYSFGRVPYPRIPLKDVVPRVEK 401
>BC104875-1|AAI04876.1| 450|Homo sapiens c-src tyrosine kinase
protein.
Length = 450
Score = 284 bits (697), Expect = 4e-76
Identities = 159/396 (40%), Positives = 229/396 (57%), Gaps = 16/396 (4%)
Query: 75 VALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTLTGAVGWVPSNYVTPVNSLEKH 134
+A Y+F E L KG+ + I++ K W +A G G +P+NYV ++
Sbjct: 15 IAKYNFHGTAEQDLPFCKGDVLTIVAVTKDPNWYKAKNKVGREGIIPANYVQKREGVKAG 74
Query: 135 S------WYHGPISRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINED 188
+ W+HG I+R AE LL G FLVRES + PG ++ + +G+V HYRI
Sbjct: 75 TKLSLMPWFHGKITREQAERLLYPPETGLFLVRESTNYPGDYTLCVSCDGKVEHYRIMYH 134
Query: 189 ADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKPTVFPLAPPDHWEIDRT 248
A K+ + E F L +LV H++ DGL T+L+ P W ++
Sbjct: 135 AS-KLSIDEEVYFENLMQLVEHYTSDADGLCTRLIKPKVMEGTVAAQDEFYRSGWALNMK 193
Query: 249 DIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASIMKEMRHPNLVQ 308
++ + +G G++GDV + RGN VAVK +K+D A + FL EAS+M ++RH NLVQ
Sbjct: 194 ELKLLQTIGKGEFGDVMLGDY-RGN-KVAVKCIKNDATA-QAFLAEASVMTQLRHSNLVQ 250
Query: 309 LLGVCTREPP-FYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIASGMSYLESRS 367
LLGV E YI+TE+M++G+L++YLR+ R + G +L + + + M YLE +
Sbjct: 251 LLGVIVEEKGGLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKF-SLDVCEAMEYLEGNN 309
Query: 368 FIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEGLAYNTFST 427
F+HRDLAARN LV E+++ KV+DFGL + + + T G K P+KWTAPE L FST
Sbjct: 310 FVHRDLAARNVLVSEDNVAKVSDFGLTK---EASSTQDTG-KLPVKWTAPEALREKKFST 365
Query: 428 KSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
KSDVW+FGILLWEI ++G PYP + L DV +EK
Sbjct: 366 KSDVWSFGILLWEIYSFGRVPYPRIPLKDVVPRVEK 401
>BC104847-1|AAI04848.1| 450|Homo sapiens c-src tyrosine kinase
protein.
Length = 450
Score = 284 bits (697), Expect = 4e-76
Identities = 159/396 (40%), Positives = 229/396 (57%), Gaps = 16/396 (4%)
Query: 75 VALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTLTGAVGWVPSNYVTPVNSLEKH 134
+A Y+F E L KG+ + I++ K W +A G G +P+NYV ++
Sbjct: 15 IAKYNFHGTAEQDLPFCKGDVLTIVAVTKDPNWYKAKNKVGREGIIPANYVQKREGVKAG 74
Query: 135 S------WYHGPISRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINED 188
+ W+HG I+R AE LL G FLVRES + PG ++ + +G+V HYRI
Sbjct: 75 TKLSLMPWFHGKITREQAERLLYPPETGLFLVRESTNYPGDYTLCVSCDGKVEHYRIMYH 134
Query: 189 ADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKPTVFPLAPPDHWEIDRT 248
A K+ + E F L +LV H++ DGL T+L+ P W ++
Sbjct: 135 AS-KLSIDEEVYFENLMQLVEHYTSDADGLCTRLIKPKVMEGTVAAQDEFYRSGWALNMK 193
Query: 249 DIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASIMKEMRHPNLVQ 308
++ + +G G++GDV + RGN VAVK +K+D A + FL EAS+M ++RH NLVQ
Sbjct: 194 ELKLLQTIGKGEFGDVMLGDY-RGN-KVAVKCIKNDATA-QAFLAEASVMTQLRHSNLVQ 250
Query: 309 LLGVCTREPP-FYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIASGMSYLESRS 367
LLGV E YI+TE+M++G+L++YLR+ R + G +L + + + M YLE +
Sbjct: 251 LLGVIVEEKGGLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKF-SLDVCEAMEYLEGNN 309
Query: 368 FIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEGLAYNTFST 427
F+HRDLAARN LV E+++ KV+DFGL + + + T G K P+KWTAPE L FST
Sbjct: 310 FVHRDLAARNVLVSEDNVAKVSDFGLTK---EASSTQDTG-KLPVKWTAPEALREKKFST 365
Query: 428 KSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
KSDVW+FGILLWEI ++G PYP + L DV +EK
Sbjct: 366 KSDVWSFGILLWEIYSFGRVPYPRIPLKDVVPRVEK 401
>AK223626-1|BAD97346.1| 449|Homo sapiens c-src tyrosine kinase
variant protein.
Length = 449
Score = 284 bits (696), Expect = 5e-76
Identities = 159/396 (40%), Positives = 228/396 (57%), Gaps = 17/396 (4%)
Query: 75 VALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTLTGAVGWVPSNYVTPVNSLEKH 134
+A Y+F E L KG+ + I++ K W +A G G +P+NYV ++
Sbjct: 15 IAKYNFHGTAEQDLPFCKGDVLTIVAVTKDPNWYKAKNKVGREGIIPANYVQKREGVKAG 74
Query: 135 S------WYHGPISRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINED 188
+ W+HG I+R AE LL G FLVRES + PG ++ + +G+V HYRI
Sbjct: 75 TKLSLMPWFHGKITREQAERLLYPPETGLFLVRESTNYPGDYTLCVSCDGKVEHYRIMYH 134
Query: 189 ADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKPTVFPLAPPDHWEIDRT 248
A K+ + E F L +LV H++ DGL T+L+ P W ++
Sbjct: 135 AS-KLSIDEEVYFENLMQLVEHYTSDADGLCTRLIKPKVMEGTVAAQDEFYRSGWALNMK 193
Query: 249 DIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASIMKEMRHPNLVQ 308
++ + +G G++GDV + RGN VAVK +K+D A + FL EAS+M ++RH NLVQ
Sbjct: 194 ELKLLQTIGKGEFGDVMLGDY-RGN-KVAVKCIKNDATA-QAFLAEASVMTQLRHSNLVQ 250
Query: 309 LLGVCTREPP-FYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIASGMSYLESRS 367
LLGV E YI+TE+M++G+L++YLR+ R + G +L + + + M YLE +
Sbjct: 251 LLGVIVEEKGGLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKF-SLDVCEAMEYLEGNN 309
Query: 368 FIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEGLAYNTFST 427
F+HRDLAARN LV E+++ KV+DFGL + + T G K P+KWTAPE L FST
Sbjct: 310 FVHRDLAARNVLVSEDNVAKVSDFGLTK----EASTQDTG-KLPVKWTAPEALREKKFST 364
Query: 428 KSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
KSDVW+FGILLWEI ++G PYP + L DV +EK
Sbjct: 365 KSDVWSFGILLWEIYSFGRVPYPRIPLKDVVPRVEK 400
>AM491361-1|CAM33011.1| 313|Homo sapiens bcr-abl1 e1a3 chimeric
protein protein.
Length = 313
Score = 280 bits (687), Expect = 7e-75
Identities = 128/172 (74%), Positives = 145/172 (84%), Gaps = 2/172 (1%)
Query: 84 GENQLTLKKGEQVRIMSYNKSGEWCEAHTLTGAVGWVPSNYVTPVNSLEKHSWYHGPISR 143
GE GE++R++ YN +GEWCEA T G GWVPSNY+TPVNSLEKHSWYHGP+SR
Sbjct: 143 GEGAFHGDAGEKLRVLGYNHNGEWCEAQTKNGQ-GWVPSNYITPVNSLEKHSWYHGPVSR 201
Query: 144 NAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINEDADGKVYVTSESKFGT 203
NAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRIN +DGK+YV+SES+F T
Sbjct: 202 NAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLYVSSESRFNT 261
Query: 204 LAELVHHHSVAGDGLITQLLYPAPKRSKPTVFPLAPP-DHWEIDRTDIVMKH 254
LAELVHHHS DGLIT L YPAPKR+KPTV+ ++P D WE++RTDI MKH
Sbjct: 262 LAELVHHHSTVADGLITTLHYPAPKRNKPTVYGVSPNYDKWEMERTDITMKH 313
>AM491359-1|CAM33009.1| 235|Homo sapiens bcr-abl1 e13a3 chimeric
protein protein.
Length = 235
Score = 280 bits (687), Expect = 7e-75
Identities = 126/165 (76%), Positives = 144/165 (87%), Gaps = 2/165 (1%)
Query: 91 KKGEQVRIMSYNKSGEWCEAHTLTGAVGWVPSNYVTPVNSLEKHSWYHGPISRNAAEYLL 150
K+GE++R++ YN +GEWCEA T G GWVPSNY+TP NSLEKHSWYHGP+SRNAAEYLL
Sbjct: 72 KEGEKLRVLGYNHNGEWCEAQTKNGQ-GWVPSNYITPANSLEKHSWYHGPVSRNAAEYLL 130
Query: 151 SSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINEDADGKVYVTSESKFGTLAELVHH 210
SSGINGSFLVRESESSPGQRSISLRYEGRVYHYRIN +DGK+YV+SES+F TLAELVHH
Sbjct: 131 SSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLYVSSESRFNTLAELVHH 190
Query: 211 HSVAGDGLITQLLYPAPKRSKPTVFPLAPP-DHWEIDRTDIVMKH 254
HS DGLIT L YPAPKR+KPTV+ ++P D WE++RTDI MKH
Sbjct: 191 HSTVADGLITTLHYPAPKRNKPTVYGVSPNYDKWEMERTDITMKH 235
>AM491360-1|CAM33010.1| 260|Homo sapiens bcr-abl1 e14a3 chimeric
protein protein.
Length = 260
Score = 277 bits (679), Expect = 6e-74
Identities = 125/162 (77%), Positives = 142/162 (87%), Gaps = 2/162 (1%)
Query: 94 EQVRIMSYNKSGEWCEAHTLTGAVGWVPSNYVTPVNSLEKHSWYHGPISRNAAEYLLSSG 153
E++R++ YN +GEWCEA T G GWVPSNY+TPVNSLEKHSWYHGP+SRNAAEYLLSSG
Sbjct: 100 EKLRVLGYNHNGEWCEAQTKNGQ-GWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSG 158
Query: 154 INGSFLVRESESSPGQRSISLRYEGRVYHYRINEDADGKVYVTSESKFGTLAELVHHHSV 213
INGSFLVRESESSPGQRSISLRYEGRVYHYRIN +DGK+YV+SES+F TLAELVHHHS
Sbjct: 159 INGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLYVSSESRFNTLAELVHHHST 218
Query: 214 AGDGLITQLLYPAPKRSKPTVFPLAPP-DHWEIDRTDIVMKH 254
DGLIT L YPAPKR+KPTV+ ++P D WE++RTDI MKH
Sbjct: 219 VADGLITTLHYPAPKRNKPTVYGVSPNYDKWEMERTDITMKH 260
>X83107-1|CAA58169.1| 675|Homo sapiens bmx protein.
Length = 675
Score = 270 bits (662), Expect = 7e-72
Identities = 142/357 (39%), Positives = 212/357 (59%), Gaps = 15/357 (4%)
Query: 111 HTLTGAVGWV--PSNYVTPVNSLEKHSWYHGPISRNAAEYLL-SSGINGSFLVRESESSP 167
HT T + W S+ +L+ + W+ G ISR+ +E LL G G+F+VR S S
Sbjct: 270 HT-TSKISWEFPESSSSEEEENLDDYDWFAGNISRSQSEQLLRQKGKEGAFMVRNS-SQV 327
Query: 168 GQRSISL------RYEGRVYHYRINEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQ 221
G ++SL +G V HY ++ +A+ K+Y+ F ++ +L+H+H G+IT+
Sbjct: 328 GMYTVSLFSKAVNDKKGTVKHYHVHTNAENKLYLAENYCFDSIPKLIHYHQHNSAGMITR 387
Query: 222 LLYPAPKRSKPTVFPLAPPDH-WEIDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKT 280
L +P ++ ++ + WE+ R +I + +LG GQ+G V WK G VAVK
Sbjct: 388 LRHPVSTKANKVPDSVSLGNGIWELKREEITLLKELGSGQFGVVQLGKWK-GQYDVAVKM 446
Query: 281 LKDDTMALKDFLEEASIMKEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGAR 340
+K+ +M+ +F +EA M ++ HP LV+ GVC++E P YI+TE++S G LL YLR+ +
Sbjct: 447 IKEGSMSEDEFFQEAQTMMKLSHPKLVKFYGVCSKEYPIYIVTEYISNGCLLNYLRSHGK 506
Query: 341 ECVPGAVVLMYMATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDD 400
P L+ M + GM++LES FIHRDLAARNCLV + VKV+DFG+ R + DD
Sbjct: 507 GLEPSQ--LLEMCYDVCEGMAFLESHQFIHRDLAARNCLVDRDLCVKVSDFGMTRYVLDD 564
Query: 401 TYTAHAGAKFPIKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADV 457
Y + G KFP+KW+APE Y +S+KSDVWAFGIL+WE+ + G PY D + V
Sbjct: 565 QYVSSVGTKFPVKWSAPEVFHYFKYSSKSDVWAFGILMWEVFSLGKQPYDLYDNSQV 621
>BC016652-1|AAH16652.1| 675|Homo sapiens BMX non-receptor tyrosine
kinase protein.
Length = 675
Score = 270 bits (662), Expect = 7e-72
Identities = 142/357 (39%), Positives = 212/357 (59%), Gaps = 15/357 (4%)
Query: 111 HTLTGAVGWV--PSNYVTPVNSLEKHSWYHGPISRNAAEYLL-SSGINGSFLVRESESSP 167
HT T + W S+ +L+ + W+ G ISR+ +E LL G G+F+VR S S
Sbjct: 270 HT-TSKISWEFPESSSSEEEENLDDYDWFAGNISRSQSEQLLRQKGKEGAFMVRNS-SQV 327
Query: 168 GQRSISL------RYEGRVYHYRINEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQ 221
G ++SL +G V HY ++ +A+ K+Y+ F ++ +L+H+H G+IT+
Sbjct: 328 GMYTVSLFSKAVNDKKGTVKHYHVHTNAENKLYLAENYCFDSIPKLIHYHQHNSAGMITR 387
Query: 222 LLYPAPKRSKPTVFPLAPPDH-WEIDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKT 280
L +P ++ ++ + WE+ R +I + +LG GQ+G V WK G VAVK
Sbjct: 388 LRHPVSTKANKVPDSVSLGNGIWELKREEITLLKELGSGQFGVVQLGKWK-GQYDVAVKM 446
Query: 281 LKDDTMALKDFLEEASIMKEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGAR 340
+K+ +M+ +F +EA M ++ HP LV+ GVC++E P YI+TE++S G LL YLR+ +
Sbjct: 447 IKEGSMSEDEFFQEAQTMMKLSHPKLVKFYGVCSKEYPIYIVTEYISNGCLLNYLRSHGK 506
Query: 341 ECVPGAVVLMYMATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDD 400
P L+ M + GM++LES FIHRDLAARNCLV + VKV+DFG+ R + DD
Sbjct: 507 GLEPSQ--LLEMCYDVCEGMAFLESHQFIHRDLAARNCLVDRDLCVKVSDFGMTRYVLDD 564
Query: 401 TYTAHAGAKFPIKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADV 457
Y + G KFP+KW+APE Y +S+KSDVWAFGIL+WE+ + G PY D + V
Sbjct: 565 QYVSSVGTKFPVKWSAPEVFHYFKYSSKSDVWAFGILMWEVFSLGKQPYDLYDNSQV 621
>X78549-1|CAA55295.1| 451|Homo sapiens tyrosine kinase protein.
Length = 451
Score = 268 bits (656), Expect = 4e-71
Identities = 153/385 (39%), Positives = 222/385 (57%), Gaps = 12/385 (3%)
Query: 74 FVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTLTG---AVGWVPSNYVTPVNS 130
+V L+DF++ + +L+ + G+ + + W G A G+VP NY+ +
Sbjct: 13 YVGLWDFKSRTDEELSFRAGDVFHVARKEEQWWWATLLDEAGGAVAQGYVPHNYLAERET 72
Query: 131 LEKHSWYHGPISRNAAEYLLSSGIN--GSFLVRESESSPGQRSISLRYEGRVYHYRINED 188
+E W+ G ISR+ A L + N G+FL+R SE +S+R V HY+I
Sbjct: 73 VESEPWFFGCISRSEAVRRLQAEGNATGAFLIRVSEKPSADYVLSVRDTQAVRHYKIWRR 132
Query: 189 ADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKPTVFPLAPPDHWEIDRT 248
A G++++ F +L ELV++H L L AP R K PL D WE R
Sbjct: 133 AGGRLHLNEAVSFLSLPELVNYHRA--QSLSHGLRLAAPCR-KHEPEPLPHWDDWERPRE 189
Query: 249 DIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLE-EASIMKEMRHPNLV 307
+ + KLG G +G+V+E WK + VA+K + D + + L+ E MK++RH +++
Sbjct: 190 EFTLCRKLGSGYFGEVFEGLWK-DRVQVAIKVISRDNLLHQQMLQSEIQAMKKLRHKHIL 248
Query: 308 QLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIASGMSYLESRS 367
L V + P YIITE M++G+LLE LR + +P + L+ +A Q+A GM YLES++
Sbjct: 249 ALYAVVSVGDPVYIITELMAKGSLLELLRDSDEKVLPVSE-LLDIAWQVAEGMCYLESQN 307
Query: 368 FIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEGLAYNTFST 427
+IHRDLAARN LVGEN L KV DFGLARL+++D Y +H P KWTAPE L+ +ST
Sbjct: 308 YIHRDLAARNILVGENTLCKVGDFGLARLIKEDVYLSH-DHNIPYKWTAPEALSRGHYST 366
Query: 428 KSDVWAFGILLWEIATYGMSPYPGV 452
KSDVW+FGILL E+ + G PYPG+
Sbjct: 367 KSDVWSFGILLHEMFSRGQVPYPGM 391
>U61412-1|AAC34935.1| 451|Homo sapiens non-receptor type protein
tyrosine kinase protein.
Length = 451
Score = 268 bits (656), Expect = 4e-71
Identities = 153/385 (39%), Positives = 222/385 (57%), Gaps = 12/385 (3%)
Query: 74 FVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTLTG---AVGWVPSNYVTPVNS 130
+V L+DF++ + +L+ + G+ + + W G A G+VP NY+ +
Sbjct: 13 YVGLWDFKSRTDEELSFRAGDVFHVARKEEQWWWATLLDEAGGAVAQGYVPHNYLAERET 72
Query: 131 LEKHSWYHGPISRNAAEYLLSSGIN--GSFLVRESESSPGQRSISLRYEGRVYHYRINED 188
+E W+ G ISR+ A L + N G+FL+R SE +S+R V HY+I
Sbjct: 73 VESEPWFFGCISRSEAVRRLQAEGNATGAFLIRVSEKPSADYVLSVRDTQAVRHYKIWRR 132
Query: 189 ADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKPTVFPLAPPDHWEIDRT 248
A G++++ F +L ELV++H L L AP R K PL D WE R
Sbjct: 133 AGGRLHLNEAVSFLSLPELVNYHRA--QSLSHGLRLAAPCR-KHEPEPLPHWDDWERPRE 189
Query: 249 DIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLE-EASIMKEMRHPNLV 307
+ + KLG G +G+V+E WK + VA+K + D + + L+ E MK++RH +++
Sbjct: 190 EFTLCRKLGSGYFGEVFEGLWK-DRVQVAIKVISRDNLLHQQMLQSEIQAMKKLRHKHIL 248
Query: 308 QLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIASGMSYLESRS 367
L V + P YIITE M++G+LLE LR + +P + L+ +A Q+A GM YLES++
Sbjct: 249 ALYAVVSVGDPVYIITELMAKGSLLELLRDSDEKVLPVSE-LLDIAWQVAEGMCYLESQN 307
Query: 368 FIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEGLAYNTFST 427
+IHRDLAARN LVGEN L KV DFGLARL+++D Y +H P KWTAPE L+ +ST
Sbjct: 308 YIHRDLAARNILVGENTLCKVGDFGLARLIKEDVYLSH-DHNIPYKWTAPEALSRGHYST 366
Query: 428 KSDVWAFGILLWEIATYGMSPYPGV 452
KSDVW+FGILL E+ + G PYPG+
Sbjct: 367 KSDVWSFGILLHEMFSRGQVPYPGM 391
>BC035843-1|AAH35843.1| 451|Homo sapiens PTK6 protein tyrosine
kinase 6 protein.
Length = 451
Score = 268 bits (656), Expect = 4e-71
Identities = 153/385 (39%), Positives = 222/385 (57%), Gaps = 12/385 (3%)
Query: 74 FVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTLTG---AVGWVPSNYVTPVNS 130
+V L+DF++ + +L+ + G+ + + W G A G+VP NY+ +
Sbjct: 13 YVGLWDFKSRTDEELSFRAGDVFHVARKEEQWWWATLLDEAGGAVAQGYVPHNYLAERET 72
Query: 131 LEKHSWYHGPISRNAAEYLLSSGIN--GSFLVRESESSPGQRSISLRYEGRVYHYRINED 188
+E W+ G ISR+ A L + N G+FL+R SE +S+R V HY+I
Sbjct: 73 VESEPWFFGCISRSEAVRRLQAEGNATGAFLIRVSEKPSADYVLSVRDTQAVRHYKIWRR 132
Query: 189 ADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKPTVFPLAPPDHWEIDRT 248
A G++++ F +L ELV++H L L AP R K PL D WE R
Sbjct: 133 AGGRLHLNEAVSFLSLPELVNYHRA--QSLSHGLRLAAPCR-KHEPEPLPHWDDWERPRE 189
Query: 249 DIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLE-EASIMKEMRHPNLV 307
+ + KLG G +G+V+E WK + VA+K + D + + L+ E MK++RH +++
Sbjct: 190 EFTLCRKLGSGYFGEVFEGLWK-DRVQVAIKVISRDNLLHQQMLQSEIQAMKKLRHKHIL 248
Query: 308 QLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIASGMSYLESRS 367
L V + P YIITE M++G+LLE LR + +P + L+ +A Q+A GM YLES++
Sbjct: 249 ALYAVVSVGDPVYIITELMAKGSLLELLRDSDEKVLPVSE-LLDIAWQVAEGMCYLESQN 307
Query: 368 FIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEGLAYNTFST 427
+IHRDLAARN LVGEN L KV DFGLARL+++D Y +H P KWTAPE L+ +ST
Sbjct: 308 YIHRDLAARNILVGENTLCKVGDFGLARLIKEDVYLSH-DHNIPYKWTAPEALSRGHYST 366
Query: 428 KSDVWAFGILLWEIATYGMSPYPGV 452
KSDVW+FGILL E+ + G PYPG+
Sbjct: 367 KSDVWSFGILLHEMFSRGQVPYPGM 391
>AL121829-13|CAC15525.1| 451|Homo sapiens Ptk6 protein.
Length = 451
Score = 268 bits (656), Expect = 4e-71
Identities = 153/385 (39%), Positives = 222/385 (57%), Gaps = 12/385 (3%)
Query: 74 FVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTLTG---AVGWVPSNYVTPVNS 130
+V L+DF++ + +L+ + G+ + + W G A G+VP NY+ +
Sbjct: 13 YVGLWDFKSRTDEELSFRAGDVFHVARKEEQWWWATLLDEAGGAVAQGYVPHNYLAERET 72
Query: 131 LEKHSWYHGPISRNAAEYLLSSGIN--GSFLVRESESSPGQRSISLRYEGRVYHYRINED 188
+E W+ G ISR+ A L + N G+FL+R SE +S+R V HY+I
Sbjct: 73 VESEPWFFGCISRSEAVRRLQAEGNATGAFLIRVSEKPSADYVLSVRDTQAVRHYKIWRR 132
Query: 189 ADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKPTVFPLAPPDHWEIDRT 248
A G++++ F +L ELV++H L L AP R K PL D WE R
Sbjct: 133 AGGRLHLNEAVSFLSLPELVNYHRA--QSLSHGLRLAAPCR-KHEPEPLPHWDDWERPRE 189
Query: 249 DIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLE-EASIMKEMRHPNLV 307
+ + KLG G +G+V+E WK + VA+K + D + + L+ E MK++RH +++
Sbjct: 190 EFTLCRKLGSGYFGEVFEGLWK-DRVQVAIKVISRDNLLHQQMLQSEIQAMKKLRHKHIL 248
Query: 308 QLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIASGMSYLESRS 367
L V + P YIITE M++G+LLE LR + +P + L+ +A Q+A GM YLES++
Sbjct: 249 ALYAVVSVGDPVYIITELMAKGSLLELLRDSDEKVLPVSE-LLDIAWQVAEGMCYLESQN 307
Query: 368 FIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEGLAYNTFST 427
+IHRDLAARN LVGEN L KV DFGLARL+++D Y +H P KWTAPE L+ +ST
Sbjct: 308 YIHRDLAARNILVGENTLCKVGDFGLARLIKEDVYLSH-DHNIPYKWTAPEALSRGHYST 366
Query: 428 KSDVWAFGILLWEIATYGMSPYPGV 452
KSDVW+FGILL E+ + G PYPG+
Sbjct: 367 KSDVWSFGILLHEMFSRGQVPYPGM 391
>AF045459-1|AAC08966.1| 697|Homo sapiens Etk/Bmx cytosolic tyrosine
kinase protein.
Length = 697
Score = 267 bits (654), Expect = 7e-71
Identities = 145/357 (40%), Positives = 211/357 (59%), Gaps = 16/357 (4%)
Query: 111 HTLTGAVGWV--PSNYVTPVNSLEKHSWYHGPISRNAAEYLL-SSGINGSFLVRESESSP 167
HT T + W S+ +L+ + W+ G ISR+ +E LL G G+F+VR S S
Sbjct: 293 HT-TSKISWEFPESSSSEEEENLDDYDWFAGNISRSQSEQLLRQKGKEGAFMVRNS-SQV 350
Query: 168 GQRSISL------RYEGRVYHYRINEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQ 221
G ++SL +G V HY ++ +A+ K+Y+ F ++ +L+H+H G+IT+
Sbjct: 351 GMYTVSLFSKAVNDKKGTVKHYHVHTNAENKLYLAENYCFDSIPKLIHYHQHNSAGMITR 410
Query: 222 LLYPAPKRSK-PTVFPLAPPDHWEIDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKT 280
+ K +K P LA WE+ R +I + +LG GQ+G V WK G VAVK
Sbjct: 411 RHPVSTKANKVPDSVSLAN-GIWELKREEITLLKELGSGQFGVVQLGKWK-GQYDVAVKM 468
Query: 281 LKDDTMALKDFLEEASIMKEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGAR 340
+K+ +M+ +F +EA M ++ HP LV+ GVC++E P YI+TE++S G LL YLR+ +
Sbjct: 469 IKEGSMSEDEFFQEAQTMMKLSHPKLVKFYGVCSKEYPIYIVTEYISNGCLLNYLRSHGK 528
Query: 341 ECVPGAVVLMYMATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDD 400
P L+ M + GM++LES FIHRDLAARNCLV + VKV+DFG+ R + DD
Sbjct: 529 GLEPSQ--LLEMCYDVCEGMAFLESHQFIHRDLAARNCLVDRDLCVKVSDFGMTRYVLDD 586
Query: 401 TYTAHAGAKFPIKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADV 457
Y + G KFP+KW+APE Y +S+KSDVWAFGIL+WE+ + G PY D + V
Sbjct: 587 QYVSSVGTKFPVKWSAPEVFHYFKYSSKSDVWAFGILMWEVFSLGKQPYDLYDNSQV 643
>X02647-1|CAA26485.1| 351|Homo sapiens c-src protein.
Length = 351
Score = 263 bits (644), Expect = 1e-69
Identities = 138/284 (48%), Positives = 187/284 (65%), Gaps = 5/284 (1%)
Query: 180 VYHYRINEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKPTVFPLAP 239
V HY+I + G Y+TS ++F +L +LV ++S DGL +L P SKP LA
Sbjct: 17 VKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPT-SKPQTQGLAK 75
Query: 240 PDHWEIDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASIMK 299
D WEI R + ++ KLG G +G+V+ W G VA+KTLK TM+ + FL+EA +MK
Sbjct: 76 -DAWEIPRESLRLEVKLGQGCFGEVWMGTWN-GTTRVAIKTLKPGTMSPEAFLQEAQVMK 133
Query: 300 EMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIASG 359
++RH LVQL V + EP YI+TE+MS+G+LL++L+ + + L+ MA QIASG
Sbjct: 134 KLRHEKLVQLYAVVSEEP-IYIVTEYMSKGSLLDFLKGETGKYLR-LPQLVDMAAQIASG 191
Query: 360 MSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEG 419
M+Y+E +++HRDL A N LVGEN + KVADFGLARL+ D+ YTA GAKFPIKWTAPE
Sbjct: 192 MAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEA 251
Query: 420 LAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
Y F+ KSDVW+FGILL E+ T G PYPG+ +V +E+
Sbjct: 252 ALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVER 295
>X58741-1|CAA41565.2| 348|Homo sapiens tyrosine kinase protein.
Length = 348
Score = 259 bits (634), Expect = 2e-68
Identities = 136/296 (45%), Positives = 194/296 (65%), Gaps = 10/296 (3%)
Query: 170 RSISLRYEGRVYHYRINEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKR 229
R R V HY+I +G Y++ S F TL ELV H+ DGL +L P
Sbjct: 7 RDYDPRQGDTVKHYKIRTLDNGGFYISPRSTFSTLQELVDHYKKGNDGLCQKLSVPCMS- 65
Query: 230 SKPTVFPLAPPDHWEIDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALK 289
SKP P D WEI R + ++ KLG GQ+G+V+ A + + + VAVKT+K +M+++
Sbjct: 66 SKPQK-PWEK-DAWEIPRESLKLEKKLGAGQFGEVWMATYNK-HTKVAVKTMKPGSMSVE 122
Query: 290 DFLEEASIMKEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRA--GARECVPGAV 347
FL EA++MK ++H LV+L V T+EP YIITEFM++G+LL++L++ G+++ +P
Sbjct: 123 AFLAEANVMKTLQHDKLVKLHAVVTKEP-IYIITEFMAKGSLLDFLKSDEGSKQPLPK-- 179
Query: 348 VLMYMATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAG 407
L+ + QIA GM+++E R++IHRDL A N LV + + K+ADFGLAR++ D+ YTA G
Sbjct: 180 -LIDFSAQIAEGMAFIEQRNYIHRDLRAANILVSASLVCKIADFGLARVIEDNEYTAREG 238
Query: 408 AKFPIKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
AKFPIKWTAPE + + +F+ KSDVW+FGILL EI TYG PYPG+ +V LE+
Sbjct: 239 AKFPIKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPEVIRALER 294
>M12724-1|AAA52762.1| 306|Homo sapiens FGR protein.
Length = 306
Score = 246 bits (602), Expect = 1e-64
Identities = 140/306 (45%), Positives = 189/306 (61%), Gaps = 13/306 (4%)
Query: 105 GEWCEAHTLT-GAVGWVPSNYVTPVNSLEKHSWYHGPISRNAAE-YLLSSGI-NGSFLVR 161
G+W EA +L+ G G +PSNYV PV+S++ WY G I R AE LLS G G+FL+R
Sbjct: 2 GDWWEARSLSSGKTGCIPSNYVAPVDSIQAEEWYFGKIGRKDAERQLLSPGNPQGAFLIR 61
Query: 162 ESESSPGQRSISLR-----YEGRVYHYRINEDADGKVYVTSESKFGTLAELVHHHSVAGD 216
ESE++ G S+S+R V HY+I + G Y+T+ +F ++ ELV H+ D
Sbjct: 62 ESETTKGAYSLSIRDWDQTRGDHVKHYKIRKLDMGGYYITTRVQFNSVQELVQHYMEVND 121
Query: 217 GLITQLLYPAPKRSKPTVFPLAPPDHWEIDRTDIVMKHKLGGGQYGDVYEAAWKRGNITV 276
GL L+ P KP LA D WEI R+ I ++ +LG G +GDV+ W G+ V
Sbjct: 122 GLCNLLIAPCTIM-KPQTLGLAK-DAWEISRSSITLERRLGTGCFGDVWLGTWN-GSTKV 178
Query: 277 AVKTLKDDTMALKDFLEEASIMKEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLR 336
AVKTLK TM+ K FLEEA +MK +RH LVQL V + EP YI+TEFM G+LL++L+
Sbjct: 179 AVKTLKPGTMSPKAFLEEAQVMKLLRHDKLVQLYAVVSEEP-IYIVTEFMCHGSLLDFLK 237
Query: 337 AGARECVPGAVVLMYMATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARL 396
+ + L+ MA Q+A GM+Y+E ++IHRDL A N LVGE K+ADFGLARL
Sbjct: 238 NPEGQDLR-LPQLVDMAAQVAEGMAYMERMNYIHRDLRAANILVGERLACKIADFGLARL 296
Query: 397 MRDDTY 402
++DD Y
Sbjct: 297 IKDDEY 302
>AM051276-1|CAJ19682.1| 319|Homo sapiens dominant-negative
kinase-deficient Brutons tyrosine kinase isoform 2
protein.
Length = 319
Score = 245 bits (600), Expect = 2e-64
Identities = 118/272 (43%), Positives = 170/272 (62%), Gaps = 6/272 (2%)
Query: 180 VYHYRINEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSK--PTVFPL 237
+ HY + + Y+ + F T+ EL+++H GLI++L YP +++K P+ L
Sbjct: 2 IRHYVVCSTPQSQYYLAEKHLFSTIPELINYHQHNSAGLISRLKYPVSQQNKNAPSTAGL 61
Query: 238 APPDHWEIDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASI 297
WEID D+ +LG GQ+G V W RG VA+K +K+ +M+ +F+EEA +
Sbjct: 62 GYGS-WEIDPKDLTFLKELGTGQFGVVKYGKW-RGQYDVAIKMIKEGSMSEDEFIEEAKV 119
Query: 298 MKEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIA 357
M + H LVQL GVCT++ P +IITE+M+ G LL YLR L+ M +
Sbjct: 120 MMNLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLREMRHRFQTQQ--LLEMCKDVC 177
Query: 358 SGMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAP 417
M YLES+ F+HRDLAARNCLV + +VKV+DFGL+R + DD YT+ G+KFP++W+ P
Sbjct: 178 EAMEYLESKQFLHRDLAARNCLVNDQGVVKVSDFGLSRYVLDDEYTSSVGSKFPVRWSPP 237
Query: 418 EGLAYNTFSTKSDVWAFGILLWEIATYGMSPY 449
E L Y+ FS+KSD+WAFG+L+WEI + G PY
Sbjct: 238 EVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPY 269
>J03358-1|AAA61190.1| 822|Homo sapiens FER protein.
Length = 822
Score = 240 bits (588), Expect = 7e-63
Identities = 134/335 (40%), Positives = 195/335 (58%), Gaps = 16/335 (4%)
Query: 131 LEKHSWYHGPISRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINEDAD 190
L + WYHG I R A+ LL G FLVRES PG+ +S+ +G+ H+ I + D
Sbjct: 455 LAEQDWYHGAIPRIEAQELLKK--QGDFLVRESHGKPGEYVLSVYSDGQRRHFII-QYVD 511
Query: 191 GKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKPTVFPLAPPDHWEIDRTDI 250
+Y + F + +L+ HH +IT+ K + P+ W + D+
Sbjct: 512 N-MYRFEGTGFSNIPQLIDHHYTTKQ-VITK------KSGVVLLNPIPKDKKWILSHEDV 563
Query: 251 VMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDT-MALK-DFLEEASIMKEMRHPNLVQ 308
++ LG G +G+VY+ K +VAVKT K+D LK FL+EA I+K+ HPN+V+
Sbjct: 564 ILGELLGKGNFGEVYKGTLK-DKTSVAVKTCKEDLPQELKIKFLQEAKILKQYDHPNIVK 622
Query: 309 LLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIASGMSYLESRSF 368
L+GVCT+ P YII E +S G+ L +LR E L+ + A+GM YLES++
Sbjct: 623 LIGVCTQRQPVYIIMELVSGGDFLTFLRRKKDELK--LKQLVKFSLDAAAGMLYLESKNC 680
Query: 369 IHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEGLAYNTFSTK 428
IHRDLAARNCLVGEN+++K++DFG++R Y++ + PIKWTAPE L Y +S++
Sbjct: 681 IHRDLAARNCLVGENNVLKISDFGMSRQEDGGVYSSSGLKQIPIKWTAPEALNYGRYSSE 740
Query: 429 SDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
SDVW+FGILLWE + G+ PYPG+ +E+
Sbjct: 741 SDVWSFGILLWETFSLGVCPYPGMTNQQAREQVER 775
>X52192-1|CAA36438.1| 822|Homo sapiens c-fes protein.
Length = 822
Score = 231 bits (565), Expect = 4e-60
Identities = 135/338 (39%), Positives = 196/338 (57%), Gaps = 22/338 (6%)
Query: 131 LEKHSWYHGPISR-NAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINEDA 189
L + WYHG I R AE L+ SG FLVRES+ + +S+ ++G H+ I +
Sbjct: 455 LHEQLWYHGAIPRAEVAELLVHSG---DFLVRESQGKQ-EYVLSVLWDGLPRHFII-QSL 509
Query: 190 DGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKPTVFPLAPPDHWEIDRTD 249
D + E F ++ L+ H L TQ P K+S + P D W ++ D
Sbjct: 510 DNLYRLEGEG-FPSIPLLIDHL------LSTQ--QPLTKKSGVVLHRAVPKDKWVLNHED 560
Query: 250 IVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMA-LK-DFLEEASIMKEMRHPNLV 307
+V+ ++G G +G+V+ + N VAVK+ ++ LK FL+EA I+K+ HPN+V
Sbjct: 561 LVLGEQIGRGNFGEVFSGRLRADNTLVAVKSCRETLPPDLKAKFLQEARILKQYSHPNIV 620
Query: 308 QLLGVCTREPPFYIITEFMSRGNLLEYLRA-GARECVPGAVVLMYMATQIASGMSYLESR 366
+L+GVCT++ P YI+ E + G+ L +LR GAR V L+ M A+GM YLES+
Sbjct: 621 RLIGVCTQKQPIYIVMELVQGGDFLTFLRTEGARLRVK---TLLQMVGDAAAGMEYLESK 677
Query: 367 SFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAK-FPIKWTAPEGLAYNTF 425
IHRDLAARNCLV E +++K++DFG++R D Y A G++ P+KWTAPE L Y +
Sbjct: 678 CCIHRDLAARNCLVTEKNVLKISDFGMSREEADGVYAASGGSRQVPVKWTAPEALNYGRY 737
Query: 426 STKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
S++SDVW+FGILLWE + G SPYP + +EK
Sbjct: 738 SSESDVWSFGILLWETFSLGASPYPNLSNQQTREFVEK 775
>AY513656-1|AAS82868.1| 764|Homo sapiens proto-oncogene c-fes
variant 3 protein.
Length = 764
Score = 231 bits (565), Expect = 4e-60
Identities = 135/338 (39%), Positives = 196/338 (57%), Gaps = 22/338 (6%)
Query: 131 LEKHSWYHGPISR-NAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINEDA 189
L + WYHG I R AE L+ SG FLVRES+ + +S+ ++G H+ I +
Sbjct: 397 LHEQLWYHGAIPRAEVAELLVHSG---DFLVRESQGKQ-EYVLSVLWDGLPRHFII-QSL 451
Query: 190 DGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKPTVFPLAPPDHWEIDRTD 249
D + E F ++ L+ H L TQ P K+S + P D W ++ D
Sbjct: 452 DNLYRLEGEG-FPSIPLLIDHL------LSTQ--QPLTKKSGVVLHRAVPKDKWVLNHED 502
Query: 250 IVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMA-LK-DFLEEASIMKEMRHPNLV 307
+V+ ++G G +G+V+ + N VAVK+ ++ LK FL+EA I+K+ HPN+V
Sbjct: 503 LVLGEQIGRGNFGEVFSGRLRADNTLVAVKSCRETLPPDLKAKFLQEARILKQYSHPNIV 562
Query: 308 QLLGVCTREPPFYIITEFMSRGNLLEYLRA-GARECVPGAVVLMYMATQIASGMSYLESR 366
+L+GVCT++ P YI+ E + G+ L +LR GAR V L+ M A+GM YLES+
Sbjct: 563 RLIGVCTQKQPIYIVMELVQGGDFLTFLRTEGARLRVK---TLLQMVGDAAAGMEYLESK 619
Query: 367 SFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAK-FPIKWTAPEGLAYNTF 425
IHRDLAARNCLV E +++K++DFG++R D Y A G++ P+KWTAPE L Y +
Sbjct: 620 CCIHRDLAARNCLVTEKNVLKISDFGMSREEADGVYAASGGSRQVPVKWTAPEALNYGRY 679
Query: 426 STKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
S++SDVW+FGILLWE + G SPYP + +EK
Sbjct: 680 SSESDVWSFGILLWETFSLGASPYPNLSNQQTREFVEK 717
>X06292-1|CAA29619.1| 822|Homo sapiens NCP92 protein.
Length = 822
Score = 230 bits (563), Expect = 7e-60
Identities = 135/338 (39%), Positives = 195/338 (57%), Gaps = 22/338 (6%)
Query: 131 LEKHSWYHGPISR-NAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINEDA 189
L + WYHG I R AE L+ SG FLVRES+ + +S+ ++G H+ I +
Sbjct: 455 LHEQLWYHGAIPRAEVAELLVHSG---DFLVRESQGKQ-EYVLSVLWDGLPRHFII-QSL 509
Query: 190 DGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKPTVFPLAPPDHWEIDRTD 249
D + E F ++ L+ H L TQ P K+S + P D W ++ D
Sbjct: 510 DNLYRLEGEG-FPSIPLLIDHL------LSTQ--QPLTKKSGVVLHRAVPKDKWVLNHED 560
Query: 250 IVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMA-LK-DFLEEASIMKEMRHPNLV 307
+V+ ++G G +G+V+ + N VAVK+ ++ LK FL+EA I+K+ HPN+V
Sbjct: 561 LVLGEQIGRGNFGEVFSGRLRADNTLVAVKSCRETLPPDLKAKFLQEARILKQYSHPNIV 620
Query: 308 QLLGVCTREPPFYIITEFMSRGNLLEYLRA-GARECVPGAVVLMYMATQIASGMSYLESR 366
+L+GVCT++ P YI+ E + G+ L +LR GAR V L+ M A+GM YLES+
Sbjct: 621 RLIGVCTQKQPIYIVMELVQGGDFLTFLRTEGARLRVK---TLLQMVGDAAAGMEYLESK 677
Query: 367 SFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAK-FPIKWTAPEGLAYNTF 425
IHRDLAARNCLV E +++K++DFG++R D Y A G + P+KWTAPE L Y +
Sbjct: 678 CCIHRDLAARNCLVTEKNVLKISDFGMSREEADGVYAASGGLRQVPVKWTAPEALNYGRY 737
Query: 426 STKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
S++SDVW+FGILLWE + G SPYP + +EK
Sbjct: 738 SSESDVWSFGILLWETFSLGASPYPNLSNQQTREFVEK 775
>BC035357-1|AAH35357.1| 822|Homo sapiens feline sarcoma oncogene
protein.
Length = 822
Score = 230 bits (563), Expect = 7e-60
Identities = 135/338 (39%), Positives = 195/338 (57%), Gaps = 22/338 (6%)
Query: 131 LEKHSWYHGPISR-NAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINEDA 189
L + WYHG I R AE L+ SG FLVRES+ + +S+ ++G H+ I +
Sbjct: 455 LHEQLWYHGAIPRAEVAELLVHSG---DFLVRESQGKQ-EYVLSVLWDGLPRHFII-QSL 509
Query: 190 DGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKPTVFPLAPPDHWEIDRTD 249
D + E F ++ L+ H L TQ P K+S + P D W ++ D
Sbjct: 510 DNLYRLEGEG-FPSIPLLIDHL------LSTQ--QPLTKKSGVVLHRAVPKDKWVLNHED 560
Query: 250 IVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMA-LK-DFLEEASIMKEMRHPNLV 307
+V+ ++G G +G+V+ + N VAVK+ ++ LK FL+EA I+K+ HPN+V
Sbjct: 561 LVLGEQIGRGNFGEVFSGRLRADNTLVAVKSCRETLPPDLKAKFLQEARILKQYSHPNIV 620
Query: 308 QLLGVCTREPPFYIITEFMSRGNLLEYLRA-GARECVPGAVVLMYMATQIASGMSYLESR 366
+L+GVCT++ P YI+ E + G+ L +LR GAR V L+ M A+GM YLES+
Sbjct: 621 RLIGVCTQKQPIYIVMELVQGGDFLTFLRTEGARLRVK---TLLQMVGDAAAGMEYLESK 677
Query: 367 SFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHAGAK-FPIKWTAPEGLAYNTF 425
IHRDLAARNCLV E +++K++DFG++R D Y A G + P+KWTAPE L Y +
Sbjct: 678 CCIHRDLAARNCLVTEKNVLKISDFGMSREEADGVYAASGGLRQVPVKWTAPEALNYGRY 737
Query: 426 STKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
S++SDVW+FGILLWE + G SPYP + +EK
Sbjct: 738 SSESDVWSFGILLWETFSLGASPYPNLSNQQTREFVEK 775
>X77278-1|CAA54493.1| 507|Homo sapiens HYL tyrosine kinase protein.
Length = 507
Score = 229 bits (561), Expect = 1e-59
Identities = 134/384 (34%), Positives = 209/384 (54%), Gaps = 17/384 (4%)
Query: 87 QLTLKKGEQVRIMSYNKSGEWCEA-HTLTGAVGWVPSNYVTPVNSLEKHS------WYHG 139
+L +KG+ V I+ ++ W H +G G + + + +L W+HG
Sbjct: 66 ELAFRKGDVVTILEACENKSWYRVKHHTSGQEGLLAAGALREREALSADPKLSLMPWFHG 125
Query: 140 PISRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINEDADGKVYVTSES 199
IS A L +G FLVRES PG + + + V HYR+ DG + +
Sbjct: 126 KISGQEAVQQLQPPEDGLFLVRESARHPGDYVLCVSFGRDVIHYRVLH-RDGHLTIDEAV 184
Query: 200 KFGTLAELVHHHSVAGDGLITQLLYPAPKRSKPTVFPLAPPDHWEIDRTDIVMKHKLGGG 259
F L ++V H+S + T+L+ P K + W ++ + + ++G G
Sbjct: 185 FFCNLMDMVEHYSKDKGAICTKLVRPKRKHGTKSAEEELARAGWLLNLQHLTLGAQIGEG 244
Query: 260 QYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASIMKEMRHPNLVQLLGVCTREPPF 319
++G V + + VAVK +K D A + FL+E ++M +M+H NLV+LLGV +
Sbjct: 245 EFGAVLQGEYLGQK--VAVKNIKCDVTA-QAFLDETAVMTKMQHENLVRLLGVILHQG-L 300
Query: 320 YIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIASGMSYLESRSFIHRDLAARNCL 379
YI+ E +S+GNL+ +LR R V A +L + + +A GM YLES+ +HRDLAARN L
Sbjct: 301 YIVMEHVSKGNLVNFLRTRGRALVNTAQLLQF-SLHVAEGMEYLESKKLVHRDLAARNIL 359
Query: 380 VGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEGLAYNTFSTKSDVWAFGILLW 439
V E+ + KV+DFGLA+ R ++ + P+KWTAPE L + F++KSDVW+FG+LLW
Sbjct: 360 VSEDLVAKVSDFGLAKAERKGLDSS----RLPVKWTAPEALKHGKFTSKSDVWSFGVLLW 415
Query: 440 EIATYGMSPYPGVDLADVYHMLEK 463
E+ +YG +PYP + L +V +EK
Sbjct: 416 EVFSYGRAPYPKMSLKEVSEAVEK 439
>S75164-1|AAC60645.1| 507|Homo sapiens megakaryocyte-associated
tyrosine kinase protein.
Length = 507
Score = 229 bits (561), Expect = 1e-59
Identities = 134/384 (34%), Positives = 209/384 (54%), Gaps = 17/384 (4%)
Query: 87 QLTLKKGEQVRIMSYNKSGEWCEA-HTLTGAVGWVPSNYVTPVNSLEKHS------WYHG 139
+L +KG+ V I+ ++ W H +G G + + + +L W+HG
Sbjct: 66 ELAFRKGDVVTILEACENKSWYRVKHHTSGQEGLLAAGALREREALSADPKLSLMPWFHG 125
Query: 140 PISRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINEDADGKVYVTSES 199
IS A L +G FLVRES PG + + + V HYR+ DG + +
Sbjct: 126 KISGQEAVQQLQPPEDGLFLVRESARHPGDYVLCVSFGRDVIHYRVLH-RDGHLTIDEAV 184
Query: 200 KFGTLAELVHHHSVAGDGLITQLLYPAPKRSKPTVFPLAPPDHWEIDRTDIVMKHKLGGG 259
F L ++V H+S + T+L+ P K + W ++ + + ++G G
Sbjct: 185 FFCNLMDMVEHYSKDKGAICTKLVRPKRKHGTKSAEEELARAGWLLNLQHLTLGAQIGEG 244
Query: 260 QYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASIMKEMRHPNLVQLLGVCTREPPF 319
++G V + + VAVK +K D A + FL+E ++M +M+H NLV+LLGV +
Sbjct: 245 EFGAVLQGEYLGQK--VAVKNIKCDVTA-QAFLDETAVMTKMQHENLVRLLGVILHQG-L 300
Query: 320 YIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIASGMSYLESRSFIHRDLAARNCL 379
YI+ E +S+GNL+ +LR R V A +L + + +A GM YLES+ +HRDLAARN L
Sbjct: 301 YIVMEHVSKGNLVNFLRTRGRALVNTAQLLQF-SLHVAEGMEYLESKKLVHRDLAARNIL 359
Query: 380 VGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEGLAYNTFSTKSDVWAFGILLW 439
V E+ + KV+DFGLA+ R ++ + P+KWTAPE L + F++KSDVW+FG+LLW
Sbjct: 360 VSEDLVAKVSDFGLAKAERKGLDSS----RLPVKWTAPEALKHGKFTSKSDVWSFGVLLW 415
Query: 440 EIATYGMSPYPGVDLADVYHMLEK 463
E+ +YG +PYP + L +V +EK
Sbjct: 416 EVFSYGRAPYPKMSLKEVSEAVEK 439
>BC003109-1|AAH03109.1| 507|Homo sapiens megakaryocyte-associated
tyrosine kinase protein.
Length = 507
Score = 229 bits (561), Expect = 1e-59
Identities = 134/384 (34%), Positives = 209/384 (54%), Gaps = 17/384 (4%)
Query: 87 QLTLKKGEQVRIMSYNKSGEWCEA-HTLTGAVGWVPSNYVTPVNSLEKHS------WYHG 139
+L +KG+ V I+ ++ W H +G G + + + +L W+HG
Sbjct: 66 ELAFRKGDVVTILEACENKSWYRVKHHTSGQEGLLAAGALREREALSADPKLSLMPWFHG 125
Query: 140 PISRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINEDADGKVYVTSES 199
IS A L +G FLVRES PG + + + V HYR+ DG + +
Sbjct: 126 KISGQEAVQQLQPPEDGLFLVRESARHPGDYVLCVSFGRDVIHYRVLH-RDGHLTIDEAV 184
Query: 200 KFGTLAELVHHHSVAGDGLITQLLYPAPKRSKPTVFPLAPPDHWEIDRTDIVMKHKLGGG 259
F L ++V H+S + T+L+ P K + W ++ + + ++G G
Sbjct: 185 FFCNLMDMVEHYSKDKGAICTKLVRPKRKHGTKSAEEELARAGWLLNLQHLTLGAQIGEG 244
Query: 260 QYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASIMKEMRHPNLVQLLGVCTREPPF 319
++G V + + VAVK +K D A + FL+E ++M +M+H NLV+LLGV +
Sbjct: 245 EFGAVLQGEYLGQK--VAVKNIKCDVTA-QAFLDETAVMTKMQHENLVRLLGVILHQG-L 300
Query: 320 YIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIASGMSYLESRSFIHRDLAARNCL 379
YI+ E +S+GNL+ +LR R V A +L + + +A GM YLES+ +HRDLAARN L
Sbjct: 301 YIVMEHVSKGNLVNFLRTRGRALVNTAQLLQF-SLHVAEGMEYLESKKLVHRDLAARNIL 359
Query: 380 VGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEGLAYNTFSTKSDVWAFGILLW 439
V E+ + KV+DFGLA+ R ++ + P+KWTAPE L + F++KSDVW+FG+LLW
Sbjct: 360 VSEDLVAKVSDFGLAKAERKGLDSS----RLPVKWTAPEALKHGKFTSKSDVWSFGVLLW 415
Query: 440 EIATYGMSPYPGVDLADVYHMLEK 463
E+ +YG +PYP + L +V +EK
Sbjct: 416 EVFSYGRAPYPKMSLKEVSEAVEK 439
>BC000114-1|AAH00114.1| 507|Homo sapiens megakaryocyte-associated
tyrosine kinase protein.
Length = 507
Score = 229 bits (561), Expect = 1e-59
Identities = 134/384 (34%), Positives = 209/384 (54%), Gaps = 17/384 (4%)
Query: 87 QLTLKKGEQVRIMSYNKSGEWCEA-HTLTGAVGWVPSNYVTPVNSLEKHS------WYHG 139
+L +KG+ V I+ ++ W H +G G + + + +L W+HG
Sbjct: 66 ELAFRKGDVVTILEACENKSWYRVKHHTSGQEGLLAAGALREREALSADPKLSLMPWFHG 125
Query: 140 PISRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINEDADGKVYVTSES 199
IS A L +G FLVRES PG + + + V HYR+ DG + +
Sbjct: 126 KISGQEAVQQLQPPEDGLFLVRESARHPGDYVLCVSFGRDVIHYRVLH-RDGHLTIDEAV 184
Query: 200 KFGTLAELVHHHSVAGDGLITQLLYPAPKRSKPTVFPLAPPDHWEIDRTDIVMKHKLGGG 259
F L ++V H+S + T+L+ P K + W ++ + + ++G G
Sbjct: 185 FFCNLMDMVEHYSKDKGAICTKLVRPKRKHGTKSAEEELARAGWLLNLQHLTLGAQIGEG 244
Query: 260 QYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASIMKEMRHPNLVQLLGVCTREPPF 319
++G V + + VAVK +K D A + FL+E ++M +M+H NLV+LLGV +
Sbjct: 245 EFGAVLQGEYLGQK--VAVKNIKCDVTA-QAFLDETAVMTKMQHENLVRLLGVILHQG-L 300
Query: 320 YIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIASGMSYLESRSFIHRDLAARNCL 379
YI+ E +S+GNL+ +LR R V A +L + + +A GM YLES+ +HRDLAARN L
Sbjct: 301 YIVMEHVSKGNLVNFLRTRGRALVNTAQLLQF-SLHVAEGMEYLESKKLVHRDLAARNIL 359
Query: 380 VGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEGLAYNTFSTKSDVWAFGILLW 439
V E+ + KV+DFGLA+ R ++ + P+KWTAPE L + F++KSDVW+FG+LLW
Sbjct: 360 VSEDLVAKVSDFGLAKAERKGLDSS----RLPVKWTAPEALKHGKFTSKSDVWSFGVLLW 415
Query: 440 EIATYGMSPYPGVDLADVYHMLEK 463
E+ +YG +PYP + L +V +EK
Sbjct: 416 EVFSYGRAPYPKMSLKEVSEAVEK 439
>AC005777-1|AAC62843.1| 507|Homo sapiens MATK_HUMAN protein.
Length = 507
Score = 229 bits (561), Expect = 1e-59
Identities = 134/384 (34%), Positives = 209/384 (54%), Gaps = 17/384 (4%)
Query: 87 QLTLKKGEQVRIMSYNKSGEWCEA-HTLTGAVGWVPSNYVTPVNSLEKHS------WYHG 139
+L +KG+ V I+ ++ W H +G G + + + +L W+HG
Sbjct: 66 ELAFRKGDVVTILEACENKSWYRVKHHTSGQEGLLAAGALREREALSADPKLSLMPWFHG 125
Query: 140 PISRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINEDADGKVYVTSES 199
IS A L +G FLVRES PG + + + V HYR+ DG + +
Sbjct: 126 KISGQEAVQQLQPPEDGLFLVRESARHPGDYVLCVSFGRDVIHYRVLH-RDGHLTIDEAV 184
Query: 200 KFGTLAELVHHHSVAGDGLITQLLYPAPKRSKPTVFPLAPPDHWEIDRTDIVMKHKLGGG 259
F L ++V H+S + T+L+ P K + W ++ + + ++G G
Sbjct: 185 FFCNLMDMVEHYSKDKGAICTKLVRPKRKHGTKSAEEELARAGWLLNLQHLTLGAQIGEG 244
Query: 260 QYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASIMKEMRHPNLVQLLGVCTREPPF 319
++G V + + VAVK +K D A + FL+E ++M +M+H NLV+LLGV +
Sbjct: 245 EFGAVLQGEYLGQK--VAVKNIKCDVTA-QAFLDETAVMTKMQHENLVRLLGVILHQG-L 300
Query: 320 YIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIASGMSYLESRSFIHRDLAARNCL 379
YI+ E +S+GNL+ +LR R V A +L + + +A GM YLES+ +HRDLAARN L
Sbjct: 301 YIVMEHVSKGNLVNFLRTRGRALVNTAQLLQF-SLHVAEGMEYLESKKLVHRDLAARNIL 359
Query: 380 VGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEGLAYNTFSTKSDVWAFGILLW 439
V E+ + KV+DFGLA+ R ++ + P+KWTAPE L + F++KSDVW+FG+LLW
Sbjct: 360 VSEDLVAKVSDFGLAKAERKGLDSS----RLPVKWTAPEALKHGKFTSKSDVWSFGVLLW 415
Query: 440 EIATYGMSPYPGVDLADVYHMLEK 463
E+ +YG +PYP + L +V +EK
Sbjct: 416 EVFSYGRAPYPKMSLKEVSEAVEK 439
>L18974-1|AAA16703.1| 527|Homo sapiens tyrosine kinase protein.
Length = 527
Score = 225 bits (551), Expect = 2e-58
Identities = 134/384 (34%), Positives = 208/384 (54%), Gaps = 18/384 (4%)
Query: 87 QLTLKKGEQVRIMSYNKSGEWCEA-HTLTGAVGWVPSNYVTPVNSLEKHS------WYHG 139
+L +KG+ V I+ ++ W H +G G + + + +L W+HG
Sbjct: 66 ELAFRKGDVVTILEACENKSWYRVKHHTSGQEGLLAAGALRDGEALSADPKLSLMPWFHG 125
Query: 140 PISRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINEDADGKVYVTSES 199
IS A L +G FLVRES PG + + + V HYR+ DG + +
Sbjct: 126 KISGQEAVQQLQPPEDGLFLVRESARHPGDYVLCVSFGRDVIHYRVLH-RDGHLTIDEAV 184
Query: 200 KFGTLAELVHHHSVAGDGLITQLLYPAPKRSKPTVFPLAPPDHWEIDRTDIVMKHKLGGG 259
F L ++V H+S + T+L+ P K + W ++ + + ++G G
Sbjct: 185 FFCNLMDMVEHYSKDKGAICTKLVRPKRKHGTKSAEEELARAGWLLNLQHLTLGAQIGEG 244
Query: 260 QYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASIMKEMRHPNLVQLLGVCTREPPF 319
++G V + + VAVK +K D A + FL+E ++M +M+H NLV+LLGV +
Sbjct: 245 EFGAVLQGEYLGQK--VAVKNIKCDVTA-QAFLDETAVMTKMQHENLVRLLGVILHQG-L 300
Query: 320 YIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIASGMSYLESRSFIHRDLAARNCL 379
YI+ E +S+GNL+ +LR R V A +L + + +A GM YLES+ +HRDLAARN L
Sbjct: 301 YIVMEHVSKGNLVNFLRTRGRALVNTAQLLQF-SLHVAEGMEYLESKKLVHRDLAARNIL 359
Query: 380 VGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEGLAYNTFSTKSDVWAFGILLW 439
V E+ + KV+DFGLA+ R ++ P+KWTAPE L + F++KSDVW+FG+LLW
Sbjct: 360 VSEDLVAKVSDFGLAKAERKGL----DSSRLPVKWTAPEALKHG-FTSKSDVWSFGVLLW 414
Query: 440 EIATYGMSPYPGVDLADVYHMLEK 463
E+ +YG +PYP + L +V +EK
Sbjct: 415 EVFSYGRAPYPKMSLKEVSEAVEK 438
>S71669-1|AAB30995.1| 465|Homo sapiens lsk protein.
Length = 465
Score = 223 bits (544), Expect = 1e-57
Identities = 131/384 (34%), Positives = 205/384 (53%), Gaps = 18/384 (4%)
Query: 87 QLTLKKGEQVRIMSYNKSGEWCEA-HTLTGAVGWVPSNYVTPVNSLEKHS------WYHG 139
+L +KG+ V I+ ++ W H +G G + + + +L W+HG
Sbjct: 25 ELAFRKGDVVTILEACENKSWYRVKHHTSGQEGLLAAGALREREALSADPKLSLMPWFHG 84
Query: 140 PISRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINEDADGKVYVTSES 199
IS A L +G FLVRES PG + + + V HYR+ DG + +
Sbjct: 85 KISGQEAVQQLQPPEDGLFLVRESGGHPGDYVLCVTFGRDVIHYRVLH-RDGHLTIDEAV 143
Query: 200 KFGTLAELVHHHSVAGDGLITQLLYPAPKRSKPTVFPLAPPDHWEIDRTDIVMKHKLGGG 259
F L ++V H+S + T+L+ P K + W ++ + + ++G G
Sbjct: 144 FFCNLMDMVEHYSKDKGAICTKLVRPKRKHGTKSAEEELARAGWLLNLQHLTLGAQIGEG 203
Query: 260 QYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASIMKEMRHPNLVQLLGVCTREPPF 319
++G V + + VK +K D A + FL+E ++M +M+H NLV+LLGV +
Sbjct: 204 EFGAVLQGEYLGQK---CVKNIKCDVTA-QAFLDETAVMTKMQHENLVRLLGVIL-DQGL 258
Query: 320 YIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIASGMSYLESRSFIHRDLAARNCL 379
YI+ E +S+GNL+ +LR R V A +L + + + GM YLES+ +HRDLAARN L
Sbjct: 259 YIVMEHVSKGNLVNFLRTRGRALVNTAQLLQF-SLHVREGMEYLESKKLVHRDLAARNIL 317
Query: 380 VGENHLVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEGLAYNTFSTKSDVWAFGILLW 439
V E + KV+DFGLA+ R ++ + P+KWTAPE L + F++KSDVW+FG+LLW
Sbjct: 318 VSEELVAKVSDFGLAKAERKGLDSS----RLPVKWTAPEALKHGKFTSKSDVWSFGVLLW 373
Query: 440 EIATYGMSPYPGVDLADVYHMLEK 463
E+ +YG +PYP + L +V +EK
Sbjct: 374 EVFSYGRAPYPKMSLKEVSEAVEK 397
>BC032496-1|AAH32496.1| 482|Homo sapiens FYN oncogene related to
SRC, FGR, YES protein.
Length = 482
Score = 212 bits (517), Expect = 3e-54
Identities = 102/199 (51%), Positives = 138/199 (69%), Gaps = 3/199 (1%)
Query: 265 YEAAWKRGNITVAVKTLKDDTMALKDFLEEASIMKEMRHPNLVQLLGVCTREPPFYIITE 324
Y W GN VA+KTLK TM+ + FLEEA IMK+++H LVQL V + EP YI+TE
Sbjct: 231 YSGTWN-GNTKVAIKTLKPGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSEEP-IYIVTE 288
Query: 325 FMSRGNLLEYLRAGARECVPGAVVLMYMATQIASGMSYLESRSFIHRDLAARNCLVGENH 384
+M++G+LL++L+ G + L+ MA Q+A+GM+Y+E ++IHRDL + N LVG
Sbjct: 289 YMNKGSLLDFLKDGEGRALK-LPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGL 347
Query: 385 LVKVADFGLARLMRDDTYTAHAGAKFPIKWTAPEGLAYNTFSTKSDVWAFGILLWEIATY 444
+ K+ADFGLARL+ D+ YTA GAKFPIKWTAPE Y F+ KSDVW+FGILL E+ T
Sbjct: 348 ICKIADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTK 407
Query: 445 GMSPYPGVDLADVYHMLEK 463
G PYPG++ +V +E+
Sbjct: 408 GRVPYPGMNNREVLEQVER 426
Score = 122 bits (294), Expect = 3e-27
Identities = 67/153 (43%), Positives = 101/153 (66%), Gaps = 9/153 (5%)
Query: 73 LFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTLT-GAVGWVPSNYVTPVNSL 131
LFVALYD++A E+ L+ KGE+ +I++ + G+W EA +LT G G++PSNYV PV+S+
Sbjct: 86 LFVALYDYEARTEDDLSFHKGEKFQILN-SSEGDWWEARSLTTGETGYIPSNYVAPVDSI 144
Query: 132 EKHSWYHGPISRNAAE-YLLSSG-INGSFLVRESESSPGQRSISLR----YEG-RVYHYR 184
+ WY G + R AE LLS G G+FL+RESE++ G S+S+R +G V HY+
Sbjct: 145 QAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESETTKGAYSLSIRDWDDMKGDHVKHYK 204
Query: 185 INEDADGKVYVTSESKFGTLAELVHHHSVAGDG 217
I + +G Y+T+ ++F TL +LV H+S +G
Sbjct: 205 IRKLDNGGYYITTRAQFETLQQLVQHYSGTWNG 237
>AY513657-1|AAS82869.1| 752|Homo sapiens proto-oncogene c-fes
variant 4 protein.
Length = 752
Score = 210 bits (514), Expect = 6e-54
Identities = 105/243 (43%), Positives = 152/243 (62%), Gaps = 7/243 (2%)
Query: 225 PAPKRSKPTVFPLAPPDHWEIDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDD 284
P K+S + P D W ++ D+V+ ++G G +G+V+ + N VAVK+ ++
Sbjct: 466 PLTKKSGVVLHRAVPKDKWVLNHEDLVLGEQIGRGNFGEVFSGRLRADNTLVAVKSCRET 525
Query: 285 TMA-LK-DFLEEASIMKEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRA-GARE 341
LK FL+EA I+K+ HPN+V+L+GVCT++ P YI+ E + G+ L +LR GAR
Sbjct: 526 LPPDLKAKFLQEARILKQYSHPNIVRLIGVCTQKQPIYIVMELVQGGDFLTFLRTEGARL 585
Query: 342 CVPGAVVLMYMATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDT 401
V L+ M A+GM YLES+ IHRDLAARNCLV E +++K++DFG++R D
Sbjct: 586 RVK---TLLQMVGDAAAGMEYLESKCCIHRDLAARNCLVTEKNVLKISDFGMSREEADGV 642
Query: 402 YTAHAGAK-FPIKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHM 460
Y A G++ P+KWTAPE L Y +S++SDVW+FGILLWE + G SPYP +
Sbjct: 643 YAASGGSRQVPVKWTAPEALNYGRYSSESDVWSFGILLWETFSLGASPYPNLSNQQTREF 702
Query: 461 LEK 463
+EK
Sbjct: 703 VEK 705
>AY513654-1|AAS82866.1| 694|Homo sapiens proto-oncogene c-fes
variant 1 protein.
Length = 694
Score = 210 bits (514), Expect = 6e-54
Identities = 105/243 (43%), Positives = 152/243 (62%), Gaps = 7/243 (2%)
Query: 225 PAPKRSKPTVFPLAPPDHWEIDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDD 284
P K+S + P D W ++ D+V+ ++G G +G+V+ + N VAVK+ ++
Sbjct: 408 PLTKKSGVVLHRAVPKDKWVLNHEDLVLGEQIGRGNFGEVFSGRLRADNTLVAVKSCRET 467
Query: 285 TMA-LK-DFLEEASIMKEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRA-GARE 341
LK FL+EA I+K+ HPN+V+L+GVCT++ P YI+ E + G+ L +LR GAR
Sbjct: 468 LPPDLKAKFLQEARILKQYSHPNIVRLIGVCTQKQPIYIVMELVQGGDFLTFLRTEGARL 527
Query: 342 CVPGAVVLMYMATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDT 401
V L+ M A+GM YLES+ IHRDLAARNCLV E +++K++DFG++R D
Sbjct: 528 RVK---TLLQMVGDAAAGMEYLESKCCIHRDLAARNCLVTEKNVLKISDFGMSREEADGV 584
Query: 402 YTAHAGAK-FPIKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHM 460
Y A G++ P+KWTAPE L Y +S++SDVW+FGILLWE + G SPYP +
Sbjct: 585 YAASGGSRQVPVKWTAPEALNYGRYSSESDVWSFGILLWETFSLGASPYPNLSNQQTREF 644
Query: 461 LEK 463
+EK
Sbjct: 645 VEK 647
>AK024281-1|BAB14871.1| 251|Homo sapiens protein ( Homo sapiens
cDNA FLJ14219 fis, clone NT2RP3003800, highly similar to
Rattus norvegicus tyrosine protein kinase pp60-c-src
mRNA. ).
Length = 251
Score = 208 bits (509), Expect = 2e-53
Identities = 103/192 (53%), Positives = 136/192 (70%), Gaps = 2/192 (1%)
Query: 272 GNITVAVKTLKDDTMALKDFLEEASIMKEMRHPNLVQLLGVCTREPPFYIITEFMSRGNL 331
G VA+KTLK TM+ + FL+EA +MK++RH LVQL V + EP YI+TE+MS+G+L
Sbjct: 6 GTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEP-IYIVTEYMSKGSL 64
Query: 332 LEYLRAGARECVPGAVVLMYMATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADF 391
L++L+ + + L+ MA QIASGM+Y+E +++HRDL A N LVGEN + KVADF
Sbjct: 65 LDFLKGETGKYLR-LPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADF 123
Query: 392 GLARLMRDDTYTAHAGAKFPIKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPG 451
GLARL+ D+ YTA GAKFPIKWTAPE Y F+ KSDVW+FGILL E+ T G PYPG
Sbjct: 124 GLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPG 183
Query: 452 VDLADVYHMLEK 463
+ +V +E+
Sbjct: 184 MVNREVLDQVER 195
>BC013200-1|AAH13200.1| 539|Homo sapiens LCK protein protein.
Length = 539
Score = 206 bits (503), Expect = 1e-52
Identities = 154/432 (35%), Positives = 230/432 (53%), Gaps = 52/432 (12%)
Query: 73 LFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTLT-GAVGWVPSNYVTPVNSL 131
L +AL+ ++ + L +KGEQ+RI+ +SGEW +A +LT G G++P N+V NSL
Sbjct: 65 LVIALHSYEPSHDGDLGFEKGEQLRILE--QSGEWWKAQSLTTGQEGFIPFNFVAKANSL 122
Query: 132 EKHSWYHGPISRNAAE-YLLSSG-INGSFLVRESESSPGQRSISLR----YEGRVY-HYR 184
E W+ +SR AE LL+ G +GSFL+RESES+ G S+S+R +G V HY+
Sbjct: 123 EPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQNQGEVVKHYK 182
Query: 185 INEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKPTVFPLAP--PDH 242
I +G Y++ F L ELV H++ A DGL T+L P + P P D
Sbjct: 183 IRNLDNGGFYISPRITFPGLHELVRHYTNASDGLCTRLSRPCQTQK-----PQKPWWEDE 237
Query: 243 WEIDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASIMKEMR 302
WE+ R + + +LG GQ+G+V+ + G+ VAVK+LK +M+ FL EA++MK+++
Sbjct: 238 WEVPRETLKLVERLGAGQFGEVW-MGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQ 296
Query: 303 HPNLVQLLGVCTREPPFYIITEFMSRGNLLE-YLRAGARECVP-GAVVLMYMATQIASGM 360
H LV+L V T+E P YIITE+M LL+ L P G + + S +
Sbjct: 297 HQRLVRLYAVVTQE-PIYIITEYMENDTLLDSQLEEKGLGASPWGNLGQQLLLLPTGSLV 355
Query: 361 SYLESRSFIH------RDLAAR----NCLVGENHLVKVADFGLARLMRDDTYTAHAGAKF 410
+L++ S I D+AA+ + E + + D A ++ DT + A F
Sbjct: 356 DFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIH-RDLRAANILVSDTLSCKI-ADF 413
Query: 411 PI-------KWTAPEG------------LAYNTFSTKSDVWAFGILLWEIATYGMSPYPG 451
+ ++TA EG + Y TF+ KSDVW+FGILL EI T+G PYPG
Sbjct: 414 GLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPG 473
Query: 452 VDLADVYHMLEK 463
+ +V LE+
Sbjct: 474 MTNPEVIQNLER 485
>AL121991-3|CAI22321.1| 526|Homo sapiens lymphocyte-specific
protein tyrosine kinase protein.
Length = 526
Score = 206 bits (503), Expect = 1e-52
Identities = 154/432 (35%), Positives = 230/432 (53%), Gaps = 52/432 (12%)
Query: 73 LFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTLT-GAVGWVPSNYVTPVNSL 131
L +AL+ ++ + L +KGEQ+RI+ +SGEW +A +LT G G++P N+V NSL
Sbjct: 52 LVIALHSYEPSHDGDLGFEKGEQLRILE--QSGEWWKAQSLTTGQEGFIPFNFVAKANSL 109
Query: 132 EKHSWYHGPISRNAAE-YLLSSG-INGSFLVRESESSPGQRSISLR----YEGRVY-HYR 184
E W+ +SR AE LL+ G +GSFL+RESES+ G S+S+R +G V HY+
Sbjct: 110 EPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQNQGEVVKHYK 169
Query: 185 INEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKPTVFPLAP--PDH 242
I +G Y++ F L ELV H++ A DGL T+L P + P P D
Sbjct: 170 IRNLDNGGFYISPRITFPGLHELVRHYTNASDGLCTRLSRPCQTQK-----PQKPWWEDE 224
Query: 243 WEIDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASIMKEMR 302
WE+ R + + +LG GQ+G+V+ + G+ VAVK+LK +M+ FL EA++MK+++
Sbjct: 225 WEVPRETLKLVERLGAGQFGEVW-MGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQ 283
Query: 303 HPNLVQLLGVCTREPPFYIITEFMSRGNLLE-YLRAGARECVP-GAVVLMYMATQIASGM 360
H LV+L V T+E P YIITE+M LL+ L P G + + S +
Sbjct: 284 HQRLVRLYAVVTQE-PIYIITEYMENDTLLDSQLEEKGLGASPWGNLGQQLLLLPTGSLV 342
Query: 361 SYLESRSFIH------RDLAAR----NCLVGENHLVKVADFGLARLMRDDTYTAHAGAKF 410
+L++ S I D+AA+ + E + + D A ++ DT + A F
Sbjct: 343 DFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIH-RDLRAANILVSDTLSCKI-ADF 400
Query: 411 PI-------KWTAPEG------------LAYNTFSTKSDVWAFGILLWEIATYGMSPYPG 451
+ ++TA EG + Y TF+ KSDVW+FGILL EI T+G PYPG
Sbjct: 401 GLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPG 460
Query: 452 VDLADVYHMLEK 463
+ +V LE+
Sbjct: 461 MTNPEVIQNLER 472
>AJ865079-1|CAI23831.1| 516|Homo sapiens proto-oncogene
tyrosine-protein kinase LCK protein.
Length = 516
Score = 200 bits (487), Expect = 1e-50
Identities = 100/194 (51%), Positives = 137/194 (70%), Gaps = 6/194 (3%)
Query: 272 GNITVAVKTLKDDTMALKDFLEEASIMKEMRHPNLVQLLGVCTREPPFYIITEFMSRGNL 331
G+ VAVK+LK +M+ FL EA++MK+++H LV+L V T+EP YIITE+M G+L
Sbjct: 273 GHTKVAVKSLKQGSMSPDAFLAEANLMKQLQHQRLVRLYAVVTQEP-IYIITEYMENGSL 331
Query: 332 LEYLR--AGARECVPGAVVLMYMATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVA 389
+++L+ +G + + L+ MA QIA GM+++E R++IHRDL A N LV + K+A
Sbjct: 332 VDFLKTPSGIKLTINK---LLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIA 388
Query: 390 DFGLARLMRDDTYTAHAGAKFPIKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPY 449
DFGLARL+ D+ YTA GAKFPIKWTAPE + Y TF+ KSDVW+FGILL EI T+G PY
Sbjct: 389 DFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPY 448
Query: 450 PGVDLADVYHMLEK 463
PG+ +V LE+
Sbjct: 449 PGMTNPEVIQNLER 462
Score = 99.5 bits (237), Expect = 2e-20
Identities = 60/148 (40%), Positives = 89/148 (60%), Gaps = 10/148 (6%)
Query: 73 LFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTLT-GAVGWVPSNYVTPVNSL 131
L +AL+ ++ + L +KGEQ+RI+ +SGEW +A +LT G G++P N+V NSL
Sbjct: 123 LVIALHSYEPSHDGDLGFEKGEQLRILE--QSGEWWKAQSLTTGQEGFIPFNFVAKANSL 180
Query: 132 EKHSWYHGPISRNAAE-YLLSSG-INGSFLVRESESSPGQRSISLR----YEGRVY-HYR 184
E W+ +SR AE LL+ G +GSFL+RESES+ G S+S+R +G V HY+
Sbjct: 181 EPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQNQGEVVKHYK 240
Query: 185 INEDADGKVYVTSESKFGTLAELVHHHS 212
I +G Y++ F L ELV H++
Sbjct: 241 IRNLDNGGFYISPRITFPGLHELVRHYT 268
>L40636-1|AAB08520.1| 984|Homo sapiens protein tyrosine kinase
protein.
Length = 984
Score = 192 bits (468), Expect = 2e-48
Identities = 98/229 (42%), Positives = 145/229 (63%), Gaps = 11/229 (4%)
Query: 244 EIDRTDIVMKHKLGGGQYGDVYEAAWK---RGNITVAVKTLKD--DTMALKDFLEEASIM 298
EID + + ++ +G G++G+VY+ K + I VA+KTLK +DFL EASIM
Sbjct: 613 EIDVSFVKIEEVIGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGYSEKQRRDFLSEASIM 672
Query: 299 KEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIAS 358
+ HPN+++L GV T+ P IITEFM G L +LR + + L+ M IA+
Sbjct: 673 GQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLRQNDGQFT--VIQLVGMLRGIAA 730
Query: 359 GMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDT----YTAHAGAKFPIKW 414
GM YL +++HRDLAARN LV N + KV+DFGL+R ++DDT YT+ G K P++W
Sbjct: 731 GMKYLAEMNYVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTSSLGGKIPVRW 790
Query: 415 TAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
TAPE +AY F++ SDVW++GI++WE+ ++G PY + DV + +E+
Sbjct: 791 TAPEAIAYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQ 839
>BC111744-1|AAI11745.1| 984|Homo sapiens EPH receptor B1 protein.
Length = 984
Score = 191 bits (465), Expect = 5e-48
Identities = 97/229 (42%), Positives = 145/229 (63%), Gaps = 11/229 (4%)
Query: 244 EIDRTDIVMKHKLGGGQYGDVYEAAWK---RGNITVAVKTLKD--DTMALKDFLEEASIM 298
EID + + ++ +G G++G+VY+ K + I VA+KTLK +DFL EASIM
Sbjct: 613 EIDVSFVKIEEVIGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGYSEKQRRDFLSEASIM 672
Query: 299 KEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIAS 358
+ HPN+++L GV T+ P IITEFM G L +LR + + L+ M IA+
Sbjct: 673 GQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLRQNDGQFT--VIQLVGMLRGIAA 730
Query: 359 GMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDT----YTAHAGAKFPIKW 414
GM YL +++HRDLAARN L+ N + KV+DFGL+R ++DDT YT+ G K P++W
Sbjct: 731 GMKYLAEMNYVHRDLAARNILLNSNLVCKVSDFGLSRYLQDDTSDPTYTSSLGGKIPVRW 790
Query: 415 TAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
TAPE +AY F++ SDVW++GI++WE+ ++G PY + DV + +E+
Sbjct: 791 TAPEAIAYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQ 839
>AF037332-1|AAD02031.1| 973|Homo sapiens Eph-like receptor tyrosine
kinase hEphB1b protein.
Length = 973
Score = 191 bits (465), Expect = 5e-48
Identities = 98/229 (42%), Positives = 144/229 (62%), Gaps = 11/229 (4%)
Query: 244 EIDRTDIVMKHKLGGGQYGDVYEAAWK---RGNITVAVKTLKD--DTMALKDFLEEASIM 298
EID + + ++ +G G++G+VY+ K + I VA+KTLK +DFL EASIM
Sbjct: 602 EIDVSFVKIEEVIGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGYSEKQRRDFLSEASIM 661
Query: 299 KEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIAS 358
+ HPN+++L GV T+ P IITEFM G L +LR + + L+ M IA+
Sbjct: 662 GQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLRQNDGQFT--VIQLVGMLRGIAA 719
Query: 359 GMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDT----YTAHAGAKFPIKW 414
GM YL +++HRDLAARN LV N + KV+DFGL+R ++DDT YT+ G K P++W
Sbjct: 720 GMKYLAEMNYVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTSSLGGKIPVRW 779
Query: 415 TAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
TAPE +AY F++ SDVW++GI +WE+ ++G PY + DV + +E+
Sbjct: 780 TAPEAIAYRKFTSASDVWSYGIRMWEVMSFGERPYWDMSNQDVINAIEQ 828
>L36643-1|AAA74244.1| 970|Homo sapiens receptor protein-tyrosine
kinase protein.
Length = 970
Score = 190 bits (464), Expect = 7e-48
Identities = 99/229 (43%), Positives = 142/229 (62%), Gaps = 11/229 (4%)
Query: 244 EIDRTDIVMKHKLGGGQYGDVYEAAWK---RGNITVAVKTLKDD--TMALKDFLEEASIM 298
EID + + ++ +G G++G+V K + I VA+KTLK +DFL EASIM
Sbjct: 599 EIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIM 658
Query: 299 KEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIAS 358
+ HPN++ L GV T+ P IITEFM G+L +LR + + L+ M IA+
Sbjct: 659 GQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFT--VIQLVGMLRGIAA 716
Query: 359 GMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDT----YTAHAGAKFPIKW 414
GM YL +++HRDLAARN LV N + KV+DFGL+R + DDT YT+ G KFPI+W
Sbjct: 717 GMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKFPIRW 776
Query: 415 TAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
TAPE + Y F++ SDVW++GI++WE+ +YG PY + DV + +E+
Sbjct: 777 TAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQ 825
>AF037331-1|AAD02030.1| 984|Homo sapiens Eph-like receptor tyrosine
kinase hEphB1 protein.
Length = 984
Score = 189 bits (461), Expect = 2e-47
Identities = 98/229 (42%), Positives = 143/229 (62%), Gaps = 11/229 (4%)
Query: 244 EIDRTDIVMKHKLGGGQYGDVYEAAWK---RGNITVAVKTLKD--DTMALKDFLEEASIM 298
EID + + ++ +G G++G+VY+ K + I VA+KTLK +DFL EASIM
Sbjct: 613 EIDVSFVKIEEVIGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGYSEKQRRDFLSEASIM 672
Query: 299 KEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIAS 358
+ HPN+++L GV T+ P IITEFM G L +LR + + L+ M IA+
Sbjct: 673 GQFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLRQNDGQFT--VIQLVGMLRGIAA 730
Query: 359 GMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDT----YTAHAGAKFPIKW 414
GM YL +++HRDLAARN LV N + KV+DFGL+R ++DDT YT+ G K P++W
Sbjct: 731 GMKYLAEMNYVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTSDPTYTSSLGGKIPVRW 790
Query: 415 TAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
TAPE +AY F++ SDVW++GI +WE+ +G PY + DV + +E+
Sbjct: 791 TAPEAIAYRKFTSASDVWSYGIHMWEVMYFGERPYWDMSNQDVINAIEQ 839
>L41939-1|AAA99310.1| 987|Homo sapiens protein-tyrosine kinase
protein.
Length = 987
Score = 188 bits (458), Expect = 4e-47
Identities = 98/229 (42%), Positives = 141/229 (61%), Gaps = 11/229 (4%)
Query: 244 EIDRTDIVMKHKLGGGQYGDVYEAAWK---RGNITVAVKTLKDD--TMALKDFLEEASIM 298
EID + + ++ +G G++G+V K + I VA+KTLK +DFL EASIM
Sbjct: 616 EIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIM 675
Query: 299 KEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIAS 358
+ HPN++ L GV T+ P IITEFM G+L +LR + + L+ M IA+
Sbjct: 676 GQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFT--VIQLVGMLRGIAA 733
Query: 359 GMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDT----YTAHAGAKFPIKW 414
GM YL +++HRDLAARN LV N + KV+DFGL+R + DDT YT+ G K PI+W
Sbjct: 734 GMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRW 793
Query: 415 TAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
TAPE + Y F++ SDVW++GI++WE+ +YG PY + DV + +E+
Sbjct: 794 TAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQ 842
>D37827-1|BAA07073.1| 478|Homo sapiens large erk/cek5 tyrosine
kinase protein.
Length = 478
Score = 188 bits (458), Expect = 4e-47
Identities = 98/229 (42%), Positives = 141/229 (61%), Gaps = 11/229 (4%)
Query: 244 EIDRTDIVMKHKLGGGQYGDVYEAAWK---RGNITVAVKTLKDD--TMALKDFLEEASIM 298
EID + + ++ +G G++G+V K + I VA+KTLK +DFL EASIM
Sbjct: 107 EIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIM 166
Query: 299 KEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIAS 358
+ HPN++ L GV T+ P IITEFM G+L +LR + + L+ M IA+
Sbjct: 167 GQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFT--VIQLVGMLRGIAA 224
Query: 359 GMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDT----YTAHAGAKFPIKW 414
GM YL +++HRDLAARN LV N + KV+DFGL+R + DDT YT+ G K PI+W
Sbjct: 225 GMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRW 284
Query: 415 TAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
TAPE + Y F++ SDVW++GI++WE+ +YG PY + DV + +E+
Sbjct: 285 TAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQ 333
>D31661-1|BAA06506.1| 981|Homo sapiens tyrosine kinase precursor
protein.
Length = 981
Score = 188 bits (458), Expect = 4e-47
Identities = 98/229 (42%), Positives = 141/229 (61%), Gaps = 11/229 (4%)
Query: 244 EIDRTDIVMKHKLGGGQYGDVYEAAWK---RGNITVAVKTLKDD--TMALKDFLEEASIM 298
EID + + ++ +G G++G+V K + I VA+KTLK +DFL EASIM
Sbjct: 610 EIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIM 669
Query: 299 KEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIAS 358
+ HPN++ L GV T+ P IITEFM G+L +LR + + L+ M IA+
Sbjct: 670 GQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFT--VIQLVGMLRGIAA 727
Query: 359 GMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDT----YTAHAGAKFPIKW 414
GM YL +++HRDLAARN LV N + KV+DFGL+R + DDT YT+ G K PI+W
Sbjct: 728 GMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRW 787
Query: 415 TAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
TAPE + Y F++ SDVW++GI++WE+ +YG PY + DV + +E+
Sbjct: 788 TAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQ 836
>AL512444-4|CAI16429.1| 1055|Homo sapiens EPH receptor B2 protein.
Length = 1055
Score = 188 bits (458), Expect = 4e-47
Identities = 98/229 (42%), Positives = 141/229 (61%), Gaps = 11/229 (4%)
Query: 244 EIDRTDIVMKHKLGGGQYGDVYEAAWK---RGNITVAVKTLKDD--TMALKDFLEEASIM 298
EID + + ++ +G G++G+V K + I VA+KTLK +DFL EASIM
Sbjct: 615 EIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIM 674
Query: 299 KEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIAS 358
+ HPN++ L GV T+ P IITEFM G+L +LR + + L+ M IA+
Sbjct: 675 GQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFT--VIQLVGMLRGIAA 732
Query: 359 GMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDT----YTAHAGAKFPIKW 414
GM YL +++HRDLAARN LV N + KV+DFGL+R + DDT YT+ G K PI+W
Sbjct: 733 GMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRW 792
Query: 415 TAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
TAPE + Y F++ SDVW++GI++WE+ +YG PY + DV + +E+
Sbjct: 793 TAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQ 841
>AL512444-3|CAI16428.1| 987|Homo sapiens EPH receptor B2 protein.
Length = 987
Score = 188 bits (458), Expect = 4e-47
Identities = 98/229 (42%), Positives = 141/229 (61%), Gaps = 11/229 (4%)
Query: 244 EIDRTDIVMKHKLGGGQYGDVYEAAWK---RGNITVAVKTLKDD--TMALKDFLEEASIM 298
EID + + ++ +G G++G+V K + I VA+KTLK +DFL EASIM
Sbjct: 616 EIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIM 675
Query: 299 KEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIAS 358
+ HPN++ L GV T+ P IITEFM G+L +LR + + L+ M IA+
Sbjct: 676 GQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFT--VIQLVGMLRGIAA 733
Query: 359 GMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDT----YTAHAGAKFPIKW 414
GM YL +++HRDLAARN LV N + KV+DFGL+R + DDT YT+ G K PI+W
Sbjct: 734 GMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRW 793
Query: 415 TAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
TAPE + Y F++ SDVW++GI++WE+ +YG PY + DV + +E+
Sbjct: 794 TAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQ 842
>AL512444-2|CAI16430.2| 986|Homo sapiens EPH receptor B2 protein.
Length = 986
Score = 188 bits (458), Expect = 4e-47
Identities = 98/229 (42%), Positives = 141/229 (61%), Gaps = 11/229 (4%)
Query: 244 EIDRTDIVMKHKLGGGQYGDVYEAAWK---RGNITVAVKTLKDD--TMALKDFLEEASIM 298
EID + + ++ +G G++G+V K + I VA+KTLK +DFL EASIM
Sbjct: 615 EIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIM 674
Query: 299 KEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIAS 358
+ HPN++ L GV T+ P IITEFM G+L +LR + + L+ M IA+
Sbjct: 675 GQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFT--VIQLVGMLRGIAA 732
Query: 359 GMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDT----YTAHAGAKFPIKW 414
GM YL +++HRDLAARN LV N + KV+DFGL+R + DDT YT+ G K PI+W
Sbjct: 733 GMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRW 792
Query: 415 TAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
TAPE + Y F++ SDVW++GI++WE+ +YG PY + DV + +E+
Sbjct: 793 TAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQ 841
>AL512444-1|CAI16427.1| 946|Homo sapiens EPH receptor B2 protein.
Length = 946
Score = 188 bits (458), Expect = 4e-47
Identities = 98/229 (42%), Positives = 141/229 (61%), Gaps = 11/229 (4%)
Query: 244 EIDRTDIVMKHKLGGGQYGDVYEAAWK---RGNITVAVKTLKDD--TMALKDFLEEASIM 298
EID + + ++ +G G++G+V K + I VA+KTLK +DFL EASIM
Sbjct: 610 EIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIM 669
Query: 299 KEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIAS 358
+ HPN++ L GV T+ P IITEFM G+L +LR + + L+ M IA+
Sbjct: 670 GQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFT--VIQLVGMLRGIAA 727
Query: 359 GMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDT----YTAHAGAKFPIKW 414
GM YL +++HRDLAARN LV N + KV+DFGL+R + DDT YT+ G K PI+W
Sbjct: 728 GMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRW 787
Query: 415 TAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
TAPE + Y F++ SDVW++GI++WE+ +YG PY + DV + +E+
Sbjct: 788 TAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQ 836
>AL158086-8|CAI22898.1| 1055|Homo sapiens EPH receptor B2 protein.
Length = 1055
Score = 188 bits (458), Expect = 4e-47
Identities = 98/229 (42%), Positives = 141/229 (61%), Gaps = 11/229 (4%)
Query: 244 EIDRTDIVMKHKLGGGQYGDVYEAAWK---RGNITVAVKTLKDD--TMALKDFLEEASIM 298
EID + + ++ +G G++G+V K + I VA+KTLK +DFL EASIM
Sbjct: 615 EIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIM 674
Query: 299 KEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIAS 358
+ HPN++ L GV T+ P IITEFM G+L +LR + + L+ M IA+
Sbjct: 675 GQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFT--VIQLVGMLRGIAA 732
Query: 359 GMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDT----YTAHAGAKFPIKW 414
GM YL +++HRDLAARN LV N + KV+DFGL+R + DDT YT+ G K PI+W
Sbjct: 733 GMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRW 792
Query: 415 TAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
TAPE + Y F++ SDVW++GI++WE+ +YG PY + DV + +E+
Sbjct: 793 TAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQ 841
>AL158086-7|CAI22899.2| 986|Homo sapiens EPH receptor B2 protein.
Length = 986
Score = 188 bits (458), Expect = 4e-47
Identities = 98/229 (42%), Positives = 141/229 (61%), Gaps = 11/229 (4%)
Query: 244 EIDRTDIVMKHKLGGGQYGDVYEAAWK---RGNITVAVKTLKDD--TMALKDFLEEASIM 298
EID + + ++ +G G++G+V K + I VA+KTLK +DFL EASIM
Sbjct: 615 EIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIM 674
Query: 299 KEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIAS 358
+ HPN++ L GV T+ P IITEFM G+L +LR + + L+ M IA+
Sbjct: 675 GQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFT--VIQLVGMLRGIAA 732
Query: 359 GMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDT----YTAHAGAKFPIKW 414
GM YL +++HRDLAARN LV N + KV+DFGL+R + DDT YT+ G K PI+W
Sbjct: 733 GMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRW 792
Query: 415 TAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
TAPE + Y F++ SDVW++GI++WE+ +YG PY + DV + +E+
Sbjct: 793 TAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQ 841
>AL158086-6|CAI22897.1| 987|Homo sapiens EPH receptor B2 protein.
Length = 987
Score = 188 bits (458), Expect = 4e-47
Identities = 98/229 (42%), Positives = 141/229 (61%), Gaps = 11/229 (4%)
Query: 244 EIDRTDIVMKHKLGGGQYGDVYEAAWK---RGNITVAVKTLKDD--TMALKDFLEEASIM 298
EID + + ++ +G G++G+V K + I VA+KTLK +DFL EASIM
Sbjct: 616 EIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIM 675
Query: 299 KEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIAS 358
+ HPN++ L GV T+ P IITEFM G+L +LR + + L+ M IA+
Sbjct: 676 GQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFT--VIQLVGMLRGIAA 733
Query: 359 GMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDT----YTAHAGAKFPIKW 414
GM YL +++HRDLAARN LV N + KV+DFGL+R + DDT YT+ G K PI+W
Sbjct: 734 GMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRW 793
Query: 415 TAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
TAPE + Y F++ SDVW++GI++WE+ +YG PY + DV + +E+
Sbjct: 794 TAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQ 842
>AL035704-4|CAI22646.1| 1055|Homo sapiens EPH receptor B2 protein.
Length = 1055
Score = 188 bits (458), Expect = 4e-47
Identities = 98/229 (42%), Positives = 141/229 (61%), Gaps = 11/229 (4%)
Query: 244 EIDRTDIVMKHKLGGGQYGDVYEAAWK---RGNITVAVKTLKDD--TMALKDFLEEASIM 298
EID + + ++ +G G++G+V K + I VA+KTLK +DFL EASIM
Sbjct: 615 EIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIM 674
Query: 299 KEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIAS 358
+ HPN++ L GV T+ P IITEFM G+L +LR + + L+ M IA+
Sbjct: 675 GQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFT--VIQLVGMLRGIAA 732
Query: 359 GMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDT----YTAHAGAKFPIKW 414
GM YL +++HRDLAARN LV N + KV+DFGL+R + DDT YT+ G K PI+W
Sbjct: 733 GMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRW 792
Query: 415 TAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
TAPE + Y F++ SDVW++GI++WE+ +YG PY + DV + +E+
Sbjct: 793 TAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQ 841
>AL035704-3|CAI22645.1| 987|Homo sapiens EPH receptor B2 protein.
Length = 987
Score = 188 bits (458), Expect = 4e-47
Identities = 98/229 (42%), Positives = 141/229 (61%), Gaps = 11/229 (4%)
Query: 244 EIDRTDIVMKHKLGGGQYGDVYEAAWK---RGNITVAVKTLKDD--TMALKDFLEEASIM 298
EID + + ++ +G G++G+V K + I VA+KTLK +DFL EASIM
Sbjct: 616 EIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIM 675
Query: 299 KEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIAS 358
+ HPN++ L GV T+ P IITEFM G+L +LR + + L+ M IA+
Sbjct: 676 GQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFT--VIQLVGMLRGIAA 733
Query: 359 GMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDT----YTAHAGAKFPIKW 414
GM YL +++HRDLAARN LV N + KV+DFGL+R + DDT YT+ G K PI+W
Sbjct: 734 GMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRW 793
Query: 415 TAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
TAPE + Y F++ SDVW++GI++WE+ +YG PY + DV + +E+
Sbjct: 794 TAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQ 842
>AL035704-2|CAI22647.2| 986|Homo sapiens EPH receptor B2 protein.
Length = 986
Score = 188 bits (458), Expect = 4e-47
Identities = 98/229 (42%), Positives = 141/229 (61%), Gaps = 11/229 (4%)
Query: 244 EIDRTDIVMKHKLGGGQYGDVYEAAWK---RGNITVAVKTLKDD--TMALKDFLEEASIM 298
EID + + ++ +G G++G+V K + I VA+KTLK +DFL EASIM
Sbjct: 615 EIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIM 674
Query: 299 KEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIAS 358
+ HPN++ L GV T+ P IITEFM G+L +LR + + L+ M IA+
Sbjct: 675 GQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFT--VIQLVGMLRGIAA 732
Query: 359 GMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDT----YTAHAGAKFPIKW 414
GM YL +++HRDLAARN LV N + KV+DFGL+R + DDT YT+ G K PI+W
Sbjct: 733 GMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRW 792
Query: 415 TAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
TAPE + Y F++ SDVW++GI++WE+ +YG PY + DV + +E+
Sbjct: 793 TAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQ 841
>AL035704-1|CAI22644.1| 946|Homo sapiens EPH receptor B2 protein.
Length = 946
Score = 188 bits (458), Expect = 4e-47
Identities = 98/229 (42%), Positives = 141/229 (61%), Gaps = 11/229 (4%)
Query: 244 EIDRTDIVMKHKLGGGQYGDVYEAAWK---RGNITVAVKTLKDD--TMALKDFLEEASIM 298
EID + + ++ +G G++G+V K + I VA+KTLK +DFL EASIM
Sbjct: 610 EIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIM 669
Query: 299 KEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIAS 358
+ HPN++ L GV T+ P IITEFM G+L +LR + + L+ M IA+
Sbjct: 670 GQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFT--VIQLVGMLRGIAA 727
Query: 359 GMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDT----YTAHAGAKFPIKW 414
GM YL +++HRDLAARN LV N + KV+DFGL+R + DDT YT+ G K PI+W
Sbjct: 728 GMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRW 787
Query: 415 TAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
TAPE + Y F++ SDVW++GI++WE+ +YG PY + DV + +E+
Sbjct: 788 TAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQ 836
>AF025304-1|AAB94602.1| 1055|Homo sapiens protein-tyrosine kinase
EPHB2v protein.
Length = 1055
Score = 188 bits (458), Expect = 4e-47
Identities = 98/229 (42%), Positives = 141/229 (61%), Gaps = 11/229 (4%)
Query: 244 EIDRTDIVMKHKLGGGQYGDVYEAAWK---RGNITVAVKTLKDD--TMALKDFLEEASIM 298
EID + + ++ +G G++G+V K + I VA+KTLK +DFL EASIM
Sbjct: 615 EIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIM 674
Query: 299 KEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIAS 358
+ HPN++ L GV T+ P IITEFM G+L +LR + + L+ M IA+
Sbjct: 675 GQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFT--VIQLVGMLRGIAA 732
Query: 359 GMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDT----YTAHAGAKFPIKW 414
GM YL +++HRDLAARN LV N + KV+DFGL+R + DDT YT+ G K PI+W
Sbjct: 733 GMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRW 792
Query: 415 TAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
TAPE + Y F++ SDVW++GI++WE+ +YG PY + DV + +E+
Sbjct: 793 TAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQ 841
>AB210018-1|BAE06100.1| 1004|Homo sapiens EPHB2 variant protein
protein.
Length = 1004
Score = 188 bits (458), Expect = 4e-47
Identities = 98/229 (42%), Positives = 141/229 (61%), Gaps = 11/229 (4%)
Query: 244 EIDRTDIVMKHKLGGGQYGDVYEAAWK---RGNITVAVKTLKDD--TMALKDFLEEASIM 298
EID + + ++ +G G++G+V K + I VA+KTLK +DFL EASIM
Sbjct: 633 EIDISCVKIEQVIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIM 692
Query: 299 KEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIAS 358
+ HPN++ L GV T+ P IITEFM G+L +LR + + L+ M IA+
Sbjct: 693 GQFDHPNVIHLEGVVTKSTPVMIITEFMENGSLDSFLRQNDGQFT--VIQLVGMLRGIAA 750
Query: 359 GMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDT----YTAHAGAKFPIKW 414
GM YL +++HRDLAARN LV N + KV+DFGL+R + DDT YT+ G K PI+W
Sbjct: 751 GMKYLADMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPTYTSALGGKIPIRW 810
Query: 415 TAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
TAPE + Y F++ SDVW++GI++WE+ +YG PY + DV + +E+
Sbjct: 811 TAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQ 859
>Z27409-1|CAA81796.1| 691|Homo sapiens receptor tyrosine kinase eph
protein.
Length = 691
Score = 186 bits (453), Expect = 1e-46
Identities = 98/226 (43%), Positives = 142/226 (62%), Gaps = 10/226 (4%)
Query: 244 EIDRTDIVMKHKLGGGQYGDVYEAAWKRGNI---TVAVKTLKDDTMALK--DFLEEASIM 298
E+D +++ +G G++G+VY + + TVA+KTLKD + + +FL EA+IM
Sbjct: 333 ELDPAWLMVDTVIGEGEFGEVYRGTLRLPSQDCKTVAIKTLKDTSPGGQWWNFLREATIM 392
Query: 299 KEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIAS 358
+ HP+++ L GV T+ P IITEFM G L +LR + VPG +V M IAS
Sbjct: 393 GQFSHPHILHLEGVVTKRKPIMIITEFMENGALDAFLREREDQLVPGQLVAMLQG--IAS 450
Query: 359 GMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRD--DTYTAHAGAKFPIKWTA 416
GM+YL + +++HRDLAARN LV +N KV+DFGL RL+ D TY G K PI+WTA
Sbjct: 451 GMNYLSNHNYVHRDLAARNILVNQNLCCKVSDFGLTRLLDDFDGTYETQGG-KIPIRWTA 509
Query: 417 PEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLE 462
PE +A+ F+T SDVW+FGI++WE+ ++G PY + +V +E
Sbjct: 510 PEAIAHRIFTTASDVWSFGIVMWEVLSFGDKPYGEMSNQEVMKSIE 555
>BC130291-1|AAI30292.1| 976|Homo sapiens EPH receptor A1 protein.
Length = 976
Score = 186 bits (453), Expect = 1e-46
Identities = 98/226 (43%), Positives = 142/226 (62%), Gaps = 10/226 (4%)
Query: 244 EIDRTDIVMKHKLGGGQYGDVYEAAWKRGNI---TVAVKTLKDDTMALK--DFLEEASIM 298
E+D +++ +G G++G+VY + + TVA+KTLKD + + +FL EA+IM
Sbjct: 618 ELDPAWLMVDTVIGEGEFGEVYRGTLRLPSQDCKTVAIKTLKDTSPGGQWWNFLREATIM 677
Query: 299 KEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIAS 358
+ HP+++ L GV T+ P IITEFM G L +LR + VPG +V M IAS
Sbjct: 678 GQFSHPHILHLEGVVTKRKPIMIITEFMENGALDAFLREREDQLVPGQLVAMLQG--IAS 735
Query: 359 GMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRD--DTYTAHAGAKFPIKWTA 416
GM+YL + +++HRDLAARN LV +N KV+DFGL RL+ D TY G K PI+WTA
Sbjct: 736 GMNYLSNHNYVHRDLAARNILVNQNLCCKVSDFGLTRLLDDFDGTYETQGG-KIPIRWTA 794
Query: 417 PEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLE 462
PE +A+ F+T SDVW+FGI++WE+ ++G PY + +V +E
Sbjct: 795 PEAIAHRIFTTASDVWSFGIVMWEVLSFGDKPYGEMSNQEVMKSIE 840
>AF101171-1|AAD43440.1| 976|Homo sapiens receptor tyrosine kinase
protein.
Length = 976
Score = 186 bits (453), Expect = 1e-46
Identities = 98/226 (43%), Positives = 142/226 (62%), Gaps = 10/226 (4%)
Query: 244 EIDRTDIVMKHKLGGGQYGDVYEAAWKRGNI---TVAVKTLKDDTMALK--DFLEEASIM 298
E+D +++ +G G++G+VY + + TVA+KTLKD + + +FL EA+IM
Sbjct: 618 ELDPAWLMVDTVIGEGEFGEVYRGTLRLPSQDCKTVAIKTLKDTSPGGQWWNFLREATIM 677
Query: 299 KEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIAS 358
+ HP+++ L GV T+ P IITEFM G L +LR + VPG +V M IAS
Sbjct: 678 GQFSHPHILHLEGVVTKRKPIMIITEFMENGALDAFLREREDQLVPGQLVAMLQG--IAS 735
Query: 359 GMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRD--DTYTAHAGAKFPIKWTA 416
GM+YL + +++HRDLAARN LV +N KV+DFGL RL+ D TY G K PI+WTA
Sbjct: 736 GMNYLSNHNYVHRDLAARNILVNQNLCCKVSDFGLTRLLDDFDGTYETQGG-KIPIRWTA 794
Query: 417 PEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLE 462
PE +A+ F+T SDVW+FGI++WE+ ++G PY + +V +E
Sbjct: 795 PEAIAHRIFTTASDVWSFGIVMWEVLSFGDKPYGEMSNQEVMKSIE 840
>AC092214-2|AAS07458.1| 976|Homo sapiens unknown protein.
Length = 976
Score = 186 bits (453), Expect = 1e-46
Identities = 98/226 (43%), Positives = 142/226 (62%), Gaps = 10/226 (4%)
Query: 244 EIDRTDIVMKHKLGGGQYGDVYEAAWKRGNI---TVAVKTLKDDTMALK--DFLEEASIM 298
E+D +++ +G G++G+VY + + TVA+KTLKD + + +FL EA+IM
Sbjct: 618 ELDPAWLMVDTVIGEGEFGEVYRGTLRLPSQDCKTVAIKTLKDTSPGGQWWNFLREATIM 677
Query: 299 KEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIAS 358
+ HP+++ L GV T+ P IITEFM G L +LR + VPG +V M IAS
Sbjct: 678 GQFSHPHILHLEGVVTKRKPIMIITEFMENGALDAFLREREDQLVPGQLVAMLQG--IAS 735
Query: 359 GMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRD--DTYTAHAGAKFPIKWTA 416
GM+YL + +++HRDLAARN LV +N KV+DFGL RL+ D TY G K PI+WTA
Sbjct: 736 GMNYLSNHNYVHRDLAARNILVNQNLCCKVSDFGLTRLLDDFDGTYETQGG-KIPIRWTA 794
Query: 417 PEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLE 462
PE +A+ F+T SDVW+FGI++WE+ ++G PY + +V +E
Sbjct: 795 PEAIAHRIFTTASDVWSFGIVMWEVLSFGDKPYGEMSNQEVMKSIE 840
>X75208-1|CAA53021.1| 998|Homo sapiens protein tyrosine
kinase-receptor protein.
Length = 998
Score = 186 bits (452), Expect = 2e-46
Identities = 97/229 (42%), Positives = 141/229 (61%), Gaps = 11/229 (4%)
Query: 244 EIDRTDIVMKHKLGGGQYGDVYEAAWK---RGNITVAVKTLKDD--TMALKDFLEEASIM 298
EID + + ++ +G G++G+V K R + VA+KTLK +DFL EASIM
Sbjct: 627 EIDVSCVKIEEVIGAGEFGEVCRGRLKQPGRREVFVAIKTLKVGYTERQRRDFLSEASIM 686
Query: 299 KEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIAS 358
+ HPN+++L GV T+ P I+TEFM L +LR + + L+ M IA+
Sbjct: 687 GQFDHPNIIRLEGVVTKSRPVMILTEFMENCALDSFLRLNDGQFT--VIQLVGMLRGIAA 744
Query: 359 GMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDD----TYTAHAGAKFPIKW 414
GM YL +++HRDLAARN LV N + KV+DFGL+R + DD TYT+ G K PI+W
Sbjct: 745 GMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDPSDPTYTSSLGGKIPIRW 804
Query: 415 TAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
TAPE +AY F++ SDVW++GI++WE+ +YG PY + DV + +E+
Sbjct: 805 TAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVINAVEQ 853
>M83941-1|AAA58633.1| 983|Homo sapiens receptor protein kinase
protein.
Length = 983
Score = 186 bits (452), Expect = 2e-46
Identities = 95/227 (41%), Positives = 141/227 (62%), Gaps = 9/227 (3%)
Query: 244 EIDRTDIVMKHKLGGGQYGDVYEAAWK---RGNITVAVKTLKDD--TMALKDFLEEASIM 298
E+D T+I + +G G++G+V K + I+VA+KTLK +DFL EASIM
Sbjct: 615 ELDATNISIDKVVGAGEFGEVCSGRLKLPSKKEISVAIKTLKVGYTEKQRRDFLGEASIM 674
Query: 299 KEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIAS 358
+ HPN+++L GV T+ P I+TE+M G+L +LR + + L+ M IAS
Sbjct: 675 GQFDHPNIIRLEGVVTKSKPVMIVTEYMENGSLDSFLRKHDAQFT--VIQLVGMLRGIAS 732
Query: 359 GMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHA--GAKFPIKWTA 416
GM YL ++HRDLAARN L+ N + KV+DFGL+R++ DD A+ G K PI+WT+
Sbjct: 733 GMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTS 792
Query: 417 PEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
PE +AY F++ SDVW++GI+LWE+ +YG PY + DV +++
Sbjct: 793 PEAIAYRKFTSASDVWSYGIVLWEVMSYGERPYWEMSNQDVIKAVDE 839
>BC063282-1|AAH63282.1| 983|Homo sapiens EPH receptor A3 protein.
Length = 983
Score = 186 bits (452), Expect = 2e-46
Identities = 95/227 (41%), Positives = 141/227 (62%), Gaps = 9/227 (3%)
Query: 244 EIDRTDIVMKHKLGGGQYGDVYEAAWK---RGNITVAVKTLKDD--TMALKDFLEEASIM 298
E+D T+I + +G G++G+V K + I+VA+KTLK +DFL EASIM
Sbjct: 615 ELDATNISIDKVVGAGEFGEVCSGRLKLPSKKEISVAIKTLKVGYTEKQRRDFLGEASIM 674
Query: 299 KEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIAS 358
+ HPN+++L GV T+ P I+TE+M G+L +LR + + L+ M IAS
Sbjct: 675 GQFDHPNIIRLEGVVTKSKPVMIVTEYMENGSLDSFLRKHDAQFT--VIQLVGMLRGIAS 732
Query: 359 GMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHA--GAKFPIKWTA 416
GM YL ++HRDLAARN L+ N + KV+DFGL+R++ DD A+ G K PI+WT+
Sbjct: 733 GMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTS 792
Query: 417 PEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
PE +AY F++ SDVW++GI+LWE+ +YG PY + DV +++
Sbjct: 793 PEAIAYRKFTSASDVWSYGIVLWEVMSYGERPYWEMSNQDVIKAVDE 839
>BC052968-1|AAH52968.1| 998|Homo sapiens EPH receptor B3 protein.
Length = 998
Score = 186 bits (452), Expect = 2e-46
Identities = 97/229 (42%), Positives = 141/229 (61%), Gaps = 11/229 (4%)
Query: 244 EIDRTDIVMKHKLGGGQYGDVYEAAWK---RGNITVAVKTLKDD--TMALKDFLEEASIM 298
EID + + ++ +G G++G+V K R + VA+KTLK +DFL EASIM
Sbjct: 627 EIDVSCVKIEEVIGAGEFGEVCRGRLKQPGRREVFVAIKTLKVGYTERQRRDFLSEASIM 686
Query: 299 KEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIAS 358
+ HPN+++L GV T+ P I+TEFM L +LR + + L+ M IA+
Sbjct: 687 GQFDHPNIIRLEGVVTKSRPVMILTEFMENCALDSFLRLNDGQFT--VIQLVGMLRGIAA 744
Query: 359 GMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDD----TYTAHAGAKFPIKW 414
GM YL +++HRDLAARN LV N + KV+DFGL+R + DD TYT+ G K PI+W
Sbjct: 745 GMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDPSDPTYTSSLGGKIPIRW 804
Query: 415 TAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
TAPE +AY F++ SDVW++GI++WE+ +YG PY + DV + +E+
Sbjct: 805 TAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVINAVEQ 853
>AF213459-1|AAG43576.1| 983|Homo sapiens ephrin receptor EPHA3
complete form protein.
Length = 983
Score = 186 bits (452), Expect = 2e-46
Identities = 95/227 (41%), Positives = 141/227 (62%), Gaps = 9/227 (3%)
Query: 244 EIDRTDIVMKHKLGGGQYGDVYEAAWK---RGNITVAVKTLKDD--TMALKDFLEEASIM 298
E+D T+I + +G G++G+V K + I+VA+KTLK +DFL EASIM
Sbjct: 615 ELDATNISIDKVVGAGEFGEVCSGRLKLPSKKEISVAIKTLKVGYTEKQRRDFLGEASIM 674
Query: 299 KEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIAS 358
+ HPN+++L GV T+ P I+TE+M G+L +LR + + L+ M IAS
Sbjct: 675 GQFDHPNIIRLEGVVTKSKPVMIVTEYMENGSLDSFLRKHDAQFT--VIQLVGMLRGIAS 732
Query: 359 GMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHA--GAKFPIKWTA 416
GM YL ++HRDLAARN L+ N + KV+DFGL+R++ DD A+ G K PI+WT+
Sbjct: 733 GMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTS 792
Query: 417 PEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
PE +AY F++ SDVW++GI+LWE+ +YG PY + DV +++
Sbjct: 793 PEAIAYRKFTSASDVWSYGIVLWEVMSYGERPYWEMSNQDVIKAVDE 839
>U23852-1|AAC50287.1| 363|Homo sapiens p56lck protein.
Length = 363
Score = 185 bits (451), Expect = 3e-46
Identities = 110/274 (40%), Positives = 166/274 (60%), Gaps = 19/274 (6%)
Query: 73 LFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTLT-GAVGWVPSNYVTPVNSL 131
L +AL+ ++ + L +KGEQ+RI+ +SGEW +A +LT G G++P N+V NSL
Sbjct: 65 LVIALHSYEPSHDGDLGFEKGEQLRILE--QSGEWWKAQSLTTGQEGFIPFNFVAKANSL 122
Query: 132 EKHSWYHGPISRNAAE-YLLSSG-INGSFLVRESESSPGQRSISLR----YEGRVY-HYR 184
E W+ +SR AE LL+ G +GSFL+RESES+ G S+S+R +G V HY+
Sbjct: 123 EPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQNQGEVVKHYK 182
Query: 185 INEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKPTVFPLAP--PDH 242
I +G Y++ F L ELV H++ A DGL T+L P + P P D
Sbjct: 183 IRNLDNGGFYISPRITFPGLHELVRHYTNASDGLCTRLSRPCQTQK-----PQKPWWEDE 237
Query: 243 WEIDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASIMKEMR 302
WE+ R + + +LG GQ+G+V+ + G+ VAVK+LK +M+ FL EA++MK+++
Sbjct: 238 WEVPRETLKLVERLGAGQFGEVW-MGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQ 296
Query: 303 HPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLR 336
H LV+L V T+E P YIITE+M G+L+++L+
Sbjct: 297 HQRLVRLYAVVTQE-PIYIITEYMENGSLVDFLK 329
>M18391-1|AAA36747.1| 984|Homo sapiens protein ( Human tyrosine
kinase receptor (eph) mRNA, complete cds. ).
Length = 984
Score = 184 bits (447), Expect = 8e-46
Identities = 97/226 (42%), Positives = 141/226 (62%), Gaps = 10/226 (4%)
Query: 244 EIDRTDIVMKHKLGGGQYGDVYEAAWKRGNI---TVAVKTLKDDTMALK--DFLEEASIM 298
E+D +++ +G G++G+VY + + TVA+KTLKD + + +FL EA+IM
Sbjct: 626 ELDPAWLMVDTVIGEGEFGEVYRGTLRLPSQDCKTVAIKTLKDTSPGGQWWNFLREATIM 685
Query: 299 KEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIAS 358
+ HP+++ L GV T+ P IITEFM L +LR + VPG +V M IAS
Sbjct: 686 GQFSHPHILHLEGVVTKRKPIMIITEFMENAALDAFLREREDQLVPGQLVAMLQG--IAS 743
Query: 359 GMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRD--DTYTAHAGAKFPIKWTA 416
GM+YL + +++HRDLAARN LV +N KV+DFGL RL+ D TY G K PI+WTA
Sbjct: 744 GMNYLSNHNYVHRDLAARNILVNQNLCCKVSDFGLTRLLDDFDGTYETQGG-KIPIRWTA 802
Query: 417 PEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLE 462
PE +A+ F+T SDVW+FGI++WE+ ++G PY + +V +E
Sbjct: 803 PEAIAHRIFTTASDVWSFGIVMWEVLSFGDKPYGEMSNQEVMKSIE 848
>L36645-1|AAA74246.1| 986|Homo sapiens receptor protein-tyrosine
kinase protein.
Length = 986
Score = 183 bits (446), Expect = 1e-45
Identities = 97/227 (42%), Positives = 138/227 (60%), Gaps = 9/227 (3%)
Query: 244 EIDRTDIVMKHKLGGGQYGDVYEAAWK---RGNITVAVKTLKDD--TMALKDFLEEASIM 298
EID + I ++ +G G++G+V K + I VA+KTLK +DFL EASIM
Sbjct: 615 EIDASCIKIEKVIGVGEFGEVCSGRLKVPGKREICVAIKTLKAGYTDKQRRDFLSEASIM 674
Query: 299 KEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIAS 358
+ HPN++ L GV T+ P IITE+M G+L +LR + L+ M I S
Sbjct: 675 GQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLRKNDGRFT--VIQLVGMLRGIGS 732
Query: 359 GMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHA--GAKFPIKWTA 416
GM YL S++HRDLAARN LV N + KV+DFG++R++ DD A+ G K PI+WTA
Sbjct: 733 GMKYLSDMSYVHRDLAARNILVNSNLVCKVSDFGMSRVLEDDPEAAYTTRGGKIPIRWTA 792
Query: 417 PEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
PE +AY F++ SDVW++GI++WE+ +YG PY + DV +E+
Sbjct: 793 PEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEE 839
>BC105002-1|AAI05003.1| 986|Homo sapiens ephrin receptor EphA4
protein.
Length = 986
Score = 183 bits (446), Expect = 1e-45
Identities = 97/227 (42%), Positives = 138/227 (60%), Gaps = 9/227 (3%)
Query: 244 EIDRTDIVMKHKLGGGQYGDVYEAAWK---RGNITVAVKTLKDD--TMALKDFLEEASIM 298
EID + I ++ +G G++G+V K + I VA+KTLK +DFL EASIM
Sbjct: 615 EIDASCIKIEKVIGVGEFGEVCSGRLKVPGKREICVAIKTLKAGYTDKQRRDFLSEASIM 674
Query: 299 KEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIAS 358
+ HPN++ L GV T+ P IITE+M G+L +LR + L+ M I S
Sbjct: 675 GQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLRKNDGRFT--VIQLVGMLRGIGS 732
Query: 359 GMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHA--GAKFPIKWTA 416
GM YL S++HRDLAARN LV N + KV+DFG++R++ DD A+ G K PI+WTA
Sbjct: 733 GMKYLSDMSYVHRDLAARNILVNSNLVCKVSDFGMSRVLEDDPEAAYTTRGGKIPIRWTA 792
Query: 417 PEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
PE +AY F++ SDVW++GI++WE+ +YG PY + DV +E+
Sbjct: 793 PEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEE 839
>BC105000-1|AAI05001.1| 986|Homo sapiens EPH receptor A4 protein.
Length = 986
Score = 183 bits (446), Expect = 1e-45
Identities = 97/227 (42%), Positives = 138/227 (60%), Gaps = 9/227 (3%)
Query: 244 EIDRTDIVMKHKLGGGQYGDVYEAAWK---RGNITVAVKTLKDD--TMALKDFLEEASIM 298
EID + I ++ +G G++G+V K + I VA+KTLK +DFL EASIM
Sbjct: 615 EIDASCIKIEKVIGVGEFGEVCSGRLKVPGKREICVAIKTLKAGYTDKQRRDFLSEASIM 674
Query: 299 KEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIAS 358
+ HPN++ L GV T+ P IITE+M G+L +LR + L+ M I S
Sbjct: 675 GQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLRKNDGRFT--VIQLVGMLRGIGS 732
Query: 359 GMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHA--GAKFPIKWTA 416
GM YL S++HRDLAARN LV N + KV+DFG++R++ DD A+ G K PI+WTA
Sbjct: 733 GMKYLSDMSYVHRDLAARNILVNSNLVCKVSDFGMSRVLEDDPEAAYTTRGGKIPIRWTA 792
Query: 417 PEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
PE +AY F++ SDVW++GI++WE+ +YG PY + DV +E+
Sbjct: 793 PEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEE 839
>BC026327-1|AAH26327.1| 949|Homo sapiens EPHA4 protein protein.
Length = 949
Score = 183 bits (446), Expect = 1e-45
Identities = 97/227 (42%), Positives = 138/227 (60%), Gaps = 9/227 (3%)
Query: 244 EIDRTDIVMKHKLGGGQYGDVYEAAWK---RGNITVAVKTLKDD--TMALKDFLEEASIM 298
EID + I ++ +G G++G+V K + I VA+KTLK +DFL EASIM
Sbjct: 615 EIDASCIKIEKVIGVGEFGEVCSGRLKVPGKREICVAIKTLKAGYTDKQRRDFLSEASIM 674
Query: 299 KEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIAS 358
+ HPN++ L GV T+ P IITE+M G+L +LR + L+ M I S
Sbjct: 675 GQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLRKNDGRFT--VIQLVGMLRGIGS 732
Query: 359 GMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHA--GAKFPIKWTA 416
GM YL S++HRDLAARN LV N + KV+DFG++R++ DD A+ G K PI+WTA
Sbjct: 733 GMKYLSDMSYVHRDLAARNILVNSNLVCKVSDFGMSRVLEDDPEAAYTTRGGKIPIRWTA 792
Query: 417 PEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
PE +AY F++ SDVW++GI++WE+ +YG PY + DV +E+
Sbjct: 793 PEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEE 839
>AC010899-2|AAY24284.1| 711|Homo sapiens unknown protein.
Length = 711
Score = 183 bits (446), Expect = 1e-45
Identities = 97/227 (42%), Positives = 138/227 (60%), Gaps = 9/227 (3%)
Query: 244 EIDRTDIVMKHKLGGGQYGDVYEAAWK---RGNITVAVKTLKDD--TMALKDFLEEASIM 298
EID + I ++ +G G++G+V K + I VA+KTLK +DFL EASIM
Sbjct: 340 EIDASCIKIEKVIGVGEFGEVCSGRLKVPGKREICVAIKTLKAGYTDKQRRDFLSEASIM 399
Query: 299 KEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIAS 358
+ HPN++ L GV T+ P IITE+M G+L +LR + L+ M I S
Sbjct: 400 GQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLRKNDGRFT--VIQLVGMLRGIGS 457
Query: 359 GMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHA--GAKFPIKWTA 416
GM YL S++HRDLAARN LV N + KV+DFG++R++ DD A+ G K PI+WTA
Sbjct: 458 GMKYLSDMSYVHRDLAARNILVNSNLVCKVSDFGMSRVLEDDPEAAYTTRGGKIPIRWTA 517
Query: 417 PEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
PE +AY F++ SDVW++GI++WE+ +YG PY + DV +E+
Sbjct: 518 PEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEE 564
>Y13901-1|CAA74200.1| 802|Homo sapiens fibroblast growth factor 4
protein.
Length = 802
Score = 183 bits (445), Expect = 1e-45
Identities = 109/245 (44%), Positives = 145/245 (59%), Gaps = 24/245 (9%)
Query: 243 WEIDRTDIVMKHKLGGGQYGDVYEA-------AWKRGNITVAVKTLKDDTMA--LKDFLE 293
WE R +V+ LG G +G V A A TVAVK LKD+ L D +
Sbjct: 460 WEFPRDRLVLGKPLGEGCFGQVVRAEAFGMDPARPDQASTVAVKMLKDNASDKDLADLVS 519
Query: 294 EASIMKEM-RHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRA-----------GAR- 340
E +MK + RH N++ LLGVCT+E P Y+I E ++GNL E+LRA G R
Sbjct: 520 EMEVMKLIGRHKNIINLLGVCTQEGPLYVIVECAAKGNLREFLRARRPPGPDLSPDGPRS 579
Query: 341 -ECVPGAVVLMYMATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRD 399
E VL+ A Q+A GM YLESR IHRDLAARN LV E++++K+ADFGLAR +
Sbjct: 580 SEGPLSFPVLVSCAYQVARGMQYLESRKCIHRDLAARNVLVTEDNVMKIADFGLARGVHH 639
Query: 400 -DTYTAHAGAKFPIKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVY 458
D Y + + P+KW APE L ++ +SDVW+FGILLWEI T G SPYPG+ + +++
Sbjct: 640 IDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDVWSFGILLWEIFTLGGSPYPGIPVEELF 699
Query: 459 HMLEK 463
+L +
Sbjct: 700 SLLRE 704
>X57205-1|CAA40490.1| 802|Homo sapiens fibroblast growth factor
receptor protein.
Length = 802
Score = 183 bits (445), Expect = 1e-45
Identities = 109/245 (44%), Positives = 145/245 (59%), Gaps = 24/245 (9%)
Query: 243 WEIDRTDIVMKHKLGGGQYGDVYEA-------AWKRGNITVAVKTLKDDTMA--LKDFLE 293
WE R +V+ LG G +G V A A TVAVK LKD+ L D +
Sbjct: 460 WEFPRDRLVLGKPLGEGCFGQVVRAEAFGMDPARPDQASTVAVKMLKDNASDKDLADLVS 519
Query: 294 EASIMKEM-RHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRA-----------GAR- 340
E +MK + RH N++ LLGVCT+E P Y+I E ++GNL E+LRA G R
Sbjct: 520 EMEVMKLIGRHKNIINLLGVCTQEGPLYVIVECAAKGNLREFLRARRPPGPDLSPDGPRS 579
Query: 341 -ECVPGAVVLMYMATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRD 399
E VL+ A Q+A GM YLESR IHRDLAARN LV E++++K+ADFGLAR +
Sbjct: 580 SEGPLSFPVLVSCAYQVARGMQYLESRKCIHRDLAARNVLVTEDNVMKIADFGLARGVHH 639
Query: 400 -DTYTAHAGAKFPIKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVY 458
D Y + + P+KW APE L ++ +SDVW+FGILLWEI T G SPYPG+ + +++
Sbjct: 640 IDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDVWSFGILLWEIFTLGGSPYPGIPVEELF 699
Query: 459 HMLEK 463
+L +
Sbjct: 700 SLLRE 704
>L03840-1|AAB59389.1| 802|Homo sapiens fibroblast growth factor
receptor 4 protein.
Length = 802
Score = 183 bits (445), Expect = 1e-45
Identities = 109/245 (44%), Positives = 145/245 (59%), Gaps = 24/245 (9%)
Query: 243 WEIDRTDIVMKHKLGGGQYGDVYEA-------AWKRGNITVAVKTLKDDTMA--LKDFLE 293
WE R +V+ LG G +G V A A TVAVK LKD+ L D +
Sbjct: 460 WEFPRDRLVLGKPLGEGCFGQVVRAEAFGMDPARPDQASTVAVKMLKDNASDKDLADLVS 519
Query: 294 EASIMKEM-RHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRA-----------GAR- 340
E +MK + RH N++ LLGVCT+E P Y+I E ++GNL E+LRA G R
Sbjct: 520 EMEVMKLIGRHKNIINLLGVCTQEGPLYVIVECAAKGNLREFLRARRPPGPDLSPDGPRS 579
Query: 341 -ECVPGAVVLMYMATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRD 399
E VL+ A Q+A GM YLESR IHRDLAARN LV E++++K+ADFGLAR +
Sbjct: 580 SEGPLSFPVLVSCAYQVARGMQYLESRKCIHRDLAARNVLVTEDNVMKIADFGLARGVHH 639
Query: 400 -DTYTAHAGAKFPIKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVY 458
D Y + + P+KW APE L ++ +SDVW+FGILLWEI T G SPYPG+ + +++
Sbjct: 640 IDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDVWSFGILLWEIFTLGGSPYPGIPVEELF 699
Query: 459 HMLEK 463
+L +
Sbjct: 700 SLLRE 704
>EF571596-1|ABQ01235.1| 802|Homo sapiens fibroblast growth factor
receptor 4 protein.
Length = 802
Score = 183 bits (445), Expect = 1e-45
Identities = 109/245 (44%), Positives = 145/245 (59%), Gaps = 24/245 (9%)
Query: 243 WEIDRTDIVMKHKLGGGQYGDVYEA-------AWKRGNITVAVKTLKDDTMA--LKDFLE 293
WE R +V+ LG G +G V A A TVAVK LKD+ L D +
Sbjct: 460 WEFPRDRLVLGKPLGEGCFGQVVRAEAFGMDPARPDQASTVAVKMLKDNASDKDLADLVS 519
Query: 294 EASIMKEM-RHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRA-----------GAR- 340
E +MK + RH N++ LLGVCT+E P Y+I E ++GNL E+LRA G R
Sbjct: 520 EMEVMKLIGRHKNIINLLGVCTQEGPLYVIVECAAKGNLREFLRARRPPGPDLSPDGPRS 579
Query: 341 -ECVPGAVVLMYMATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRD 399
E VL+ A Q+A GM YLESR IHRDLAARN LV E++++K+ADFGLAR +
Sbjct: 580 SEGPLSFPVLVSCAYQVARGMQYLESRKCIHRDLAARNVLVTEDNVMKIADFGLARGVHH 639
Query: 400 -DTYTAHAGAKFPIKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVY 458
D Y + + P+KW APE L ++ +SDVW+FGILLWEI T G SPYPG+ + +++
Sbjct: 640 IDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDVWSFGILLWEIFTLGGSPYPGIPVEELF 699
Query: 459 HMLEK 463
+L +
Sbjct: 700 SLLRE 704
>BC011847-1|AAH11847.1| 802|Homo sapiens fibroblast growth factor
receptor 4 protein.
Length = 802
Score = 183 bits (445), Expect = 1e-45
Identities = 109/245 (44%), Positives = 145/245 (59%), Gaps = 24/245 (9%)
Query: 243 WEIDRTDIVMKHKLGGGQYGDVYEA-------AWKRGNITVAVKTLKDDTMA--LKDFLE 293
WE R +V+ LG G +G V A A TVAVK LKD+ L D +
Sbjct: 460 WEFPRDRLVLGKPLGEGCFGQVVRAEAFGMDPARPDQASTVAVKMLKDNASDKDLADLVS 519
Query: 294 EASIMKEM-RHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRA-----------GAR- 340
E +MK + RH N++ LLGVCT+E P Y+I E ++GNL E+LRA G R
Sbjct: 520 EMEVMKLIGRHKNIINLLGVCTQEGPLYVIVECAAKGNLREFLRARRPPGPDLSPDGPRS 579
Query: 341 -ECVPGAVVLMYMATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRD 399
E VL+ A Q+A GM YLESR IHRDLAARN LV E++++K+ADFGLAR +
Sbjct: 580 SEGPLSFPVLVSCAYQVARGMQYLESRKCIHRDLAARNVLVTEDNVMKIADFGLARGVHH 639
Query: 400 -DTYTAHAGAKFPIKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVY 458
D Y + + P+KW APE L ++ +SDVW+FGILLWEI T G SPYPG+ + +++
Sbjct: 640 IDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDVWSFGILLWEIFTLGGSPYPGIPVEELF 699
Query: 459 HMLEK 463
+L +
Sbjct: 700 SLLRE 704
>AF487555-1|AAM13666.1| 802|Homo sapiens fibroblast growth factor
receptor 4 protein.
Length = 802
Score = 183 bits (445), Expect = 1e-45
Identities = 109/245 (44%), Positives = 145/245 (59%), Gaps = 24/245 (9%)
Query: 243 WEIDRTDIVMKHKLGGGQYGDVYEA-------AWKRGNITVAVKTLKDDTMA--LKDFLE 293
WE R +V+ LG G +G V A A TVAVK LKD+ L D +
Sbjct: 460 WEFPRDRLVLGKPLGEGCFGQVVRAEAFGMDPARPDQASTVAVKMLKDNASDKDLADLVS 519
Query: 294 EASIMKEM-RHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRA-----------GAR- 340
E +MK + RH N++ LLGVCT+E P Y+I E ++GNL E+LRA G R
Sbjct: 520 EMEVMKLIGRHKNIINLLGVCTQEGPLYVIVECAAKGNLREFLRARRPPGPDLSPDGPRS 579
Query: 341 -ECVPGAVVLMYMATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRD 399
E VL+ A Q+A GM YLESR IHRDLAARN LV E++++K+ADFGLAR +
Sbjct: 580 SEGPLSFPVLVSCAYQVARGMQYLESRKCIHRDLAARNVLVTEDNVMKIADFGLARGVHH 639
Query: 400 -DTYTAHAGAKFPIKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVY 458
D Y + + P+KW APE L ++ +SDVW+FGILLWEI T G SPYPG+ + +++
Sbjct: 640 IDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDVWSFGILLWEIFTLGGSPYPGIPVEELF 699
Query: 459 HMLEK 463
+L +
Sbjct: 700 SLLRE 704
>AF359246-1|AAK51435.1| 592|Homo sapiens fibroblast growth factor
receptor 4 variant protein.
Length = 592
Score = 183 bits (445), Expect = 1e-45
Identities = 109/245 (44%), Positives = 145/245 (59%), Gaps = 24/245 (9%)
Query: 243 WEIDRTDIVMKHKLGGGQYGDVYEA-------AWKRGNITVAVKTLKDDTMA--LKDFLE 293
WE R +V+ LG G +G V A A TVAVK LKD+ L D +
Sbjct: 250 WEFPRDRLVLGKPLGEGCFGQVVRAEAFGMDPARPDQASTVAVKMLKDNASDKDLADLVS 309
Query: 294 EASIMKEM-RHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRA-----------GAR- 340
E +MK + RH N++ LLGVCT+E P Y+I E ++GNL E+LRA G R
Sbjct: 310 EMEVMKLIGRHKNIINLLGVCTQEGPLYVIVECAAKGNLREFLRARRPPGPDLSPDGPRS 369
Query: 341 -ECVPGAVVLMYMATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRD 399
E VL+ A Q+A GM YLESR IHRDLAARN LV E++++K+ADFGLAR +
Sbjct: 370 SEGPLSFPVLVSCAYQVARGMQYLESRKCIHRDLAARNVLVTEDNVMKIADFGLARGVHH 429
Query: 400 -DTYTAHAGAKFPIKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVY 458
D Y + + P+KW APE L ++ +SDVW+FGILLWEI T G SPYPG+ + +++
Sbjct: 430 IDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDVWSFGILLWEIFTLGGSPYPGIPVEELF 489
Query: 459 HMLEK 463
+L +
Sbjct: 490 SLLRE 494
>AF202063-1|AAF27432.1| 762|Homo sapiens fibroblast growth factor
receptor 4, soluble-form splice variant protein.
Length = 762
Score = 183 bits (445), Expect = 1e-45
Identities = 109/245 (44%), Positives = 145/245 (59%), Gaps = 24/245 (9%)
Query: 243 WEIDRTDIVMKHKLGGGQYGDVYEA-------AWKRGNITVAVKTLKDDTMA--LKDFLE 293
WE R +V+ LG G +G V A A TVAVK LKD+ L D +
Sbjct: 420 WEFPRDRLVLGKPLGEGCFGQVVRAEAFGMDPARPDQASTVAVKMLKDNASDKDLADLVS 479
Query: 294 EASIMKEM-RHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRA-----------GAR- 340
E +MK + RH N++ LLGVCT+E P Y+I E ++GNL E+LRA G R
Sbjct: 480 EMEVMKLIGRHKNIINLLGVCTQEGPLYVIVECAAKGNLREFLRARRPPGPDLSPDGPRS 539
Query: 341 -ECVPGAVVLMYMATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRD 399
E VL+ A Q+A GM YLESR IHRDLAARN LV E++++K+ADFGLAR +
Sbjct: 540 SEGPLSFPVLVSCAYQVARGMQYLESRKCIHRDLAARNVLVTEDNVMKIADFGLARGVHH 599
Query: 400 -DTYTAHAGAKFPIKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVY 458
D Y + + P+KW APE L ++ +SDVW+FGILLWEI T G SPYPG+ + +++
Sbjct: 600 IDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDVWSFGILLWEIFTLGGSPYPGIPVEELF 659
Query: 459 HMLEK 463
+L +
Sbjct: 660 SLLRE 664
>AB209631-1|BAD92868.1| 1034|Homo sapiens Fibroblast growth factor
receptor 4 variant protein.
Length = 1034
Score = 183 bits (445), Expect = 1e-45
Identities = 109/245 (44%), Positives = 145/245 (59%), Gaps = 24/245 (9%)
Query: 243 WEIDRTDIVMKHKLGGGQYGDVYEA-------AWKRGNITVAVKTLKDDTMA--LKDFLE 293
WE R +V+ LG G +G V A A TVAVK LKD+ L D +
Sbjct: 692 WEFPRDRLVLGKPLGEGCFGQVVRAEAFGMDPARPDQASTVAVKMLKDNASDKDLADLVS 751
Query: 294 EASIMKEM-RHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRA-----------GAR- 340
E +MK + RH N++ LLGVCT+E P Y+I E ++GNL E+LRA G R
Sbjct: 752 EMEVMKLIGRHKNIINLLGVCTQEGPLYVIVECAAKGNLREFLRARRPPGPDLSPDGPRS 811
Query: 341 -ECVPGAVVLMYMATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRD 399
E VL+ A Q+A GM YLESR IHRDLAARN LV E++++K+ADFGLAR +
Sbjct: 812 SEGPLSFPVLVSCAYQVARGMQYLESRKCIHRDLAARNVLVTEDNVMKIADFGLARGVHH 871
Query: 400 -DTYTAHAGAKFPIKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVY 458
D Y + + P+KW APE L ++ +SDVW+FGILLWEI T G SPYPG+ + +++
Sbjct: 872 IDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDVWSFGILLWEIFTLGGSPYPGIPVEELF 931
Query: 459 HMLEK 463
+L +
Sbjct: 932 SLLRE 936
>L08961-1|AAC41766.1| 600|Homo sapiens tyrosine kinase protein.
Length = 600
Score = 180 bits (439), Expect = 7e-45
Identities = 105/230 (45%), Positives = 140/230 (60%), Gaps = 15/230 (6%)
Query: 245 IDRTDIVMKHKLGGGQYGDVYEAAW-----KRGNITVAVKTLKDDTMALKDFLEEASIMK 299
IDR +++ LG G+ G VYE W K I VA+KTLK DTMA K+ L+EAS+MK
Sbjct: 237 IDRNLLILGKILGEGEKGTVYEGLWNIPEGKEVKIPVAIKTLKLDTMANKEILDEASVMK 296
Query: 300 EMRHPNLVQLLGVCTREPPFYIITEF---MSRGNL--LEYLRAGARECVPGAVVLMYMAT 354
+P++V+LLG+C Y+ITE+ + R N E R+ E P L+
Sbjct: 297 GFGNPHVVRLLGICMTST-IYVITEYCLLVYRRNKDKAEQHRSNCAELNPPLQTLLKFMV 355
Query: 355 QIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLA-RLMRDDTYTAHAGAKFPIK 413
IA GM YL +R+F+HRDLAARNC++ ++ V VADFGL+ ++ D Y AK P+K
Sbjct: 356 DIALGMEYLSNRNFLHRDLAARNCMLRDDMTVCVADFGLSKKIYSGDYYRQGRIAKMPVK 415
Query: 414 WTAPEGLAYNTFSTKSDVWAFGILLWEIAT--YGMSPYPGVDLADVYHML 461
W A E LA + TKSDVWAFG+ +WEIAT GM+PYPGV ++Y L
Sbjct: 416 WIAIESLADRVY-TKSDVWAFGVTMWEIATTLRGMTPYPGVQNHEMYDYL 464
>AF041811-1|AAC12728.2| 408|Homo sapiens ETS related protein-growth
factor receptor tyrosine kinase fusion proteins protein.
Length = 408
Score = 180 bits (439), Expect = 7e-45
Identities = 104/268 (38%), Positives = 151/268 (56%), Gaps = 23/268 (8%)
Query: 202 GTLAELVHHHSVAGDGLITQLLYPAPKRSKPTVFPLAPPDHWEIDRTDIVMKHKLGGGQY 261
G L H +A I + P + + P + +A H I R DIV+K +LG G +
Sbjct: 76 GKPINLSHREDLAYMNHIMVSVSPPEEHAMP-IGRIADVQH--IKRRDIVLKRELGEGAF 132
Query: 262 GDV-----YEAAWKRGNITVAVKTLKDDTMAL-KDFLEEASIMKEMRHPNLVQLLGVCTR 315
G V Y + + + VAVK LKD T+A KDF EA ++ ++H ++V+ GVC
Sbjct: 133 GKVFLAECYNLSPTKDKMLVAVKALKDPTLAARKDFQREAELLTNLQHEHIVKFYGVCGD 192
Query: 316 EPPFYIITEFMSRGNLLEYLRAGARECV------P-------GAVVLMYMATQIASGMSY 362
P ++ E+M G+L ++LRA + + P G ++++A+QIASGM Y
Sbjct: 193 GDPLIMVFEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGELGLSQMLHIASQIASGMVY 252
Query: 363 LESRSFIHRDLAARNCLVGENHLVKVADFGLAR-LMRDDTYTAHAGAKFPIKWTAPEGLA 421
L S+ F+HRDLA RNCLVG N LVK+ DFG++R + D Y PI+W PE +
Sbjct: 253 LASQHFVHRDLATRNCLVGANLLVKIGDFGMSRDVYSTDYYRVGGHTMLPIRWMPPESIM 312
Query: 422 YNTFSTKSDVWAFGILLWEIATYGMSPY 449
Y F+T+SDVW+FG++LWEI TYG P+
Sbjct: 313 YRKFTTESDVWSFGVILWEIFTYGKQPW 340
>X57019-1|CAA40338.1| 894|Homo sapiens protein ( H.sapiens mRNA for
tyrosine kinase receptor. ).
Length = 894
Score = 180 bits (438), Expect = 1e-44
Identities = 103/235 (43%), Positives = 145/235 (61%), Gaps = 17/235 (7%)
Query: 245 IDRTDIVMKHKLGGGQYGDVYEAAWKRGN--ITVAVKTLKDDTMA---LKDFLEEASIMK 299
+DR + + LG G++G V E + + + VAVKT+K L+DFL EA MK
Sbjct: 531 VDRHKVALGKTLGEGEFGAVMEGQLNQDDSILKVAVKTMKIAICTRSELEDFLSEAVCMK 590
Query: 300 EMRHPNLVQLLGVC----TRE--PPFYIITEFMSRGNL---LEYLRAGAREC-VPGAVVL 349
E HPN+++L+GVC RE P +I FM G+L L Y R G + +P +++
Sbjct: 591 EFDHPNVMRLIGVCFQGSERESFPAPVVILPFMKHGDLHSFLLYSRLGGQPVYLPTQMLV 650
Query: 350 MYMATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLAR-LMRDDTYTAHAGA 408
+MA IASGM YL ++ FIHRDLAARNC++ EN V VADFGL++ + D Y A
Sbjct: 651 KFMA-DIASGMEYLSTKRFIHRDLAARNCMLNENMSVCVADFGLSKKIYNGDYYRQGRIA 709
Query: 409 KFPIKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
K P+KW A E LA +++KSDVW+FG+ +WEIAT G +PYPGV+ +++Y L +
Sbjct: 710 KMPVKWIAIESLADRVYTSKSDVWSFGVTMWEIATRGQTPYPGVENSEIYDYLRQ 764
>U07695-1|AAA20598.1| 987|Homo sapiens tyrosine kinase protein.
Length = 987
Score = 180 bits (438), Expect = 1e-44
Identities = 94/229 (41%), Positives = 138/229 (60%), Gaps = 11/229 (4%)
Query: 244 EIDRTDIVMKHKLGGGQYGDVYEAAWK---RGNITVAVKTLKDD--TMALKDFLEEASIM 298
EID + + ++ +G G++G+V K + VA+KTLK ++FL EASIM
Sbjct: 609 EIDVSYVKIEEVIGAGEFGEVCRGRLKAPGKKESCVAIKTLKGGYTERQRREFLSEASIM 668
Query: 299 KEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIAS 358
+ HPN+++L GV T P I+TEFM G L +LR + + L+ M IAS
Sbjct: 669 GQFEHPNIIRLEGVVTNSMPVMILTEFMENGALDSFLRLNDGQFT--VIQLVGMLRGIAS 726
Query: 359 GMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMR----DDTYTAHAGAKFPIKW 414
GM YL S++HRDLAARN LV N + KV+DFGL+R + D TYT+ G K PI+W
Sbjct: 727 GMRYLAEMSYVHRDLAARNILVNSNLVCKVSDFGLSRFLEENSSDPTYTSSLGGKIPIRW 786
Query: 415 TAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
TAPE +A+ F++ SD W++GI++WE+ ++G PY + DV + +E+
Sbjct: 787 TAPEAIAFRKFTSASDAWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQ 835
>S65125-1|AAB20305.1| 894|Homo sapiens UFO protein.
Length = 894
Score = 180 bits (438), Expect = 1e-44
Identities = 103/235 (43%), Positives = 145/235 (61%), Gaps = 17/235 (7%)
Query: 245 IDRTDIVMKHKLGGGQYGDVYEAAWKRGN--ITVAVKTLKDDTMA---LKDFLEEASIMK 299
+DR + + LG G++G V E + + + VAVKT+K L+DFL EA MK
Sbjct: 531 VDRHKVALGKTLGEGEFGAVMEGQLNQDDSILKVAVKTMKIAICTRSELEDFLSEAVCMK 590
Query: 300 EMRHPNLVQLLGVC----TRE--PPFYIITEFMSRGNL---LEYLRAGAREC-VPGAVVL 349
E HPN+++L+GVC RE P +I FM G+L L Y R G + +P +++
Sbjct: 591 EFDHPNVMRLIGVCFQGSERESFPAPVVILPFMKHGDLHSFLLYSRLGGQPVYLPTQMLV 650
Query: 350 MYMATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLAR-LMRDDTYTAHAGA 408
+MA IASGM YL ++ FIHRDLAARNC++ EN V VADFGL++ + D Y A
Sbjct: 651 KFMA-DIASGMEYLSTKRFIHRDLAARNCMLNENMSVCVADFGLSKKIYNGDYYRQGRIA 709
Query: 409 KFPIKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
K P+KW A E LA +++KSDVW+FG+ +WEIAT G +PYPGV+ +++Y L +
Sbjct: 710 KMPVKWIAIESLADRVYTSKSDVWSFGVTMWEIATRGQTPYPGVENSEIYDYLRQ 764
>BC052804-1|AAH52804.1| 987|Homo sapiens EPH receptor B4 protein.
Length = 987
Score = 180 bits (438), Expect = 1e-44
Identities = 94/229 (41%), Positives = 138/229 (60%), Gaps = 11/229 (4%)
Query: 244 EIDRTDIVMKHKLGGGQYGDVYEAAWK---RGNITVAVKTLKDD--TMALKDFLEEASIM 298
EID + + ++ +G G++G+V K + VA+KTLK ++FL EASIM
Sbjct: 609 EIDVSYVKIEEVIGAGEFGEVCRGRLKAPGKKESCVAIKTLKGGYTERQRREFLSEASIM 668
Query: 299 KEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIAS 358
+ HPN+++L GV T P I+TEFM G L +LR + + L+ M IAS
Sbjct: 669 GQFEHPNIIRLEGVVTNSMPVMILTEFMENGALDSFLRLNDGQFT--VIQLVGMLRGIAS 726
Query: 359 GMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMR----DDTYTAHAGAKFPIKW 414
GM YL S++HRDLAARN LV N + KV+DFGL+R + D TYT+ G K PI+W
Sbjct: 727 GMRYLAEMSYVHRDLAARNILVNSNLVCKVSDFGLSRFLEENSSDPTYTSSLGGKIPIRW 786
Query: 415 TAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
TAPE +A+ F++ SD W++GI++WE+ ++G PY + DV + +E+
Sbjct: 787 TAPEAIAFRKFTSASDAWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQ 835
>BC004264-1|AAH04264.1| 845|Homo sapiens EPHB4 protein protein.
Length = 845
Score = 180 bits (438), Expect = 1e-44
Identities = 94/229 (41%), Positives = 138/229 (60%), Gaps = 11/229 (4%)
Query: 244 EIDRTDIVMKHKLGGGQYGDVYEAAWK---RGNITVAVKTLKDD--TMALKDFLEEASIM 298
EID + + ++ +G G++G+V K + VA+KTLK ++FL EASIM
Sbjct: 467 EIDVSYVKIEEVIGAGEFGEVCRGRLKAPGKKESCVAIKTLKGGYTERQRREFLSEASIM 526
Query: 299 KEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIAS 358
+ HPN+++L GV T P I+TEFM G L +LR + + L+ M IAS
Sbjct: 527 GQFEHPNIIRLEGVVTNSMPVMILTEFMENGALDSFLRLNDGQFT--VIQLVGMLRGIAS 584
Query: 359 GMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMR----DDTYTAHAGAKFPIKW 414
GM YL S++HRDLAARN LV N + KV+DFGL+R + D TYT+ G K PI+W
Sbjct: 585 GMRYLAEMSYVHRDLAARNILVNSNLVCKVSDFGLSRFLEENSSDPTYTSSLGGKIPIRW 644
Query: 415 TAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
TAPE +A+ F++ SD W++GI++WE+ ++G PY + DV + +E+
Sbjct: 645 TAPEAIAFRKFTSASDAWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQ 693
>AY056048-1|AAL14195.1| 935|Homo sapiens receptor protein tyrosine
kinase variant EphB4v1 protein.
Length = 935
Score = 180 bits (438), Expect = 1e-44
Identities = 94/229 (41%), Positives = 138/229 (60%), Gaps = 11/229 (4%)
Query: 244 EIDRTDIVMKHKLGGGQYGDVYEAAWK---RGNITVAVKTLKDD--TMALKDFLEEASIM 298
EID + + ++ +G G++G+V K + VA+KTLK ++FL EASIM
Sbjct: 609 EIDVSYVKIEEVIGAGEFGEVCRGRLKAPGKKESCVAIKTLKGGYTERQRREFLSEASIM 668
Query: 299 KEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIAS 358
+ HPN+++L GV T P I+TEFM G L +LR + + L+ M IAS
Sbjct: 669 GQFEHPNIIRLEGVVTNSMPVMILTEFMENGALDSFLRLNDGQFT--VIQLVGMLRGIAS 726
Query: 359 GMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMR----DDTYTAHAGAKFPIKW 414
GM YL S++HRDLAARN LV N + KV+DFGL+R + D TYT+ G K PI+W
Sbjct: 727 GMRYLAEMSYVHRDLAARNILVNSNLVCKVSDFGLSRFLEENSSDPTYTSSLGGKIPIRW 786
Query: 415 TAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
TAPE +A+ F++ SD W++GI++WE+ ++G PY + DV + +E+
Sbjct: 787 TAPEAIAFRKFTSASDAWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQ 835
>AY056047-1|AAL14194.1| 987|Homo sapiens receptor protein tyrosine
kinase EphB4 protein.
Length = 987
Score = 180 bits (438), Expect = 1e-44
Identities = 94/229 (41%), Positives = 138/229 (60%), Gaps = 11/229 (4%)
Query: 244 EIDRTDIVMKHKLGGGQYGDVYEAAWK---RGNITVAVKTLKDD--TMALKDFLEEASIM 298
EID + + ++ +G G++G+V K + VA+KTLK ++FL EASIM
Sbjct: 609 EIDVSYVKIEEVIGAGEFGEVCRGRLKAPGKKESCVAIKTLKGGYTERQRREFLSEASIM 668
Query: 299 KEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIAS 358
+ HPN+++L GV T P I+TEFM G L +LR + + L+ M IAS
Sbjct: 669 GQFEHPNIIRLEGVVTNSMPVMILTEFMENGALDSFLRLNDGQFT--VIQLVGMLRGIAS 726
Query: 359 GMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMR----DDTYTAHAGAKFPIKW 414
GM YL S++HRDLAARN LV N + KV+DFGL+R + D TYT+ G K PI+W
Sbjct: 727 GMRYLAEMSYVHRDLAARNILVNSNLVCKVSDFGLSRFLEENSSDPTYTSSLGGKIPIRW 786
Query: 415 TAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
TAPE +A+ F++ SD W++GI++WE+ ++G PY + DV + +E+
Sbjct: 787 TAPEAIAFRKFTSASDAWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQ 835
>AL031729-2|CAI19617.1| 313|Homo sapiens Gardner-Rasheed feline
sarcoma viral (v-fgr) oncogene homolog protein.
Length = 313
Score = 180 bits (438), Expect = 1e-44
Identities = 104/235 (44%), Positives = 142/235 (60%), Gaps = 12/235 (5%)
Query: 73 LFVALYDFQAGGENQLTLKKGEQVRIMSYNKSGEWCEAHTLT-GAVGWVPSNYVTPVNSL 131
LF+ALYD++A E+ LT KGE+ I++ N G+W EA +L+ G G +PSNYV PV+S+
Sbjct: 81 LFIALYDYEARTEDDLTFTKGEKFHILN-NTEGDWWEARSLSSGKTGCIPSNYVAPVDSI 139
Query: 132 EKHSWYHGPISRNAAE-YLLSSG-INGSFLVRESESSPGQRSISLR-----YEGRVYHYR 184
+ WY G I R AE LLS G G+FL+RESE++ G S+S+R V HY+
Sbjct: 140 QAEEWYFGKIGRKDAERQLLSPGNPQGAFLIRESETTKGAYSLSIRDWDQTRGDHVKHYK 199
Query: 185 INEDADGKVYVTSESKFGTLAELVHHHSVAGDGLITQLLYPAPKRSKPTVFPLAPPDHWE 244
I + G Y+T+ +F ++ ELV H+ DGL L+ P KP LA D WE
Sbjct: 200 IRKLDMGGYYITTRVQFNSVQELVQHYMEVNDGLCNLLIAPC-TIMKPQTLGLA-KDAWE 257
Query: 245 IDRTDIVMKHKLGGGQYGDVYEAAWKRGNITVAVKTLKDDTMALKDFLEEASIMK 299
I R+ I ++ +LG G +GDV+ W G+ VAVKTLK TM+ K FLEEA +MK
Sbjct: 258 ISRSSITLERRLGTGCFGDVWLGTW-NGSTKVAVKTLKPGTMSPKAFLEEAQVMK 311
>AF312032-8|AAK21010.1| 987|Homo sapiens ephrin type-B receptor 4
precursor protein.
Length = 987
Score = 180 bits (438), Expect = 1e-44
Identities = 94/229 (41%), Positives = 138/229 (60%), Gaps = 11/229 (4%)
Query: 244 EIDRTDIVMKHKLGGGQYGDVYEAAWK---RGNITVAVKTLKDD--TMALKDFLEEASIM 298
EID + + ++ +G G++G+V K + VA+KTLK ++FL EASIM
Sbjct: 609 EIDVSYVKIEEVIGAGEFGEVCRGRLKAPGKKESCVAIKTLKGGYTERQRREFLSEASIM 668
Query: 299 KEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIAS 358
+ HPN+++L GV T P I+TEFM G L +LR + + L+ M IAS
Sbjct: 669 GQFEHPNIIRLEGVVTNSMPVMILTEFMENGALDSFLRLNDGQFT--VIQLVGMLRGIAS 726
Query: 359 GMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMR----DDTYTAHAGAKFPIKW 414
GM YL S++HRDLAARN LV N + KV+DFGL+R + D TYT+ G K PI+W
Sbjct: 727 GMRYLAEMSYVHRDLAARNILVNSNLVCKVSDFGLSRFLEENSSDPTYTSSLGGKIPIRW 786
Query: 415 TAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
TAPE +A+ F++ SD W++GI++WE+ ++G PY + DV + +E+
Sbjct: 787 TAPEAIAFRKFTSASDAWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQ 835
>AB209644-1|BAD92881.1| 986|Homo sapiens ephrin receptor EphB4
precursor variant protein.
Length = 986
Score = 180 bits (438), Expect = 1e-44
Identities = 94/229 (41%), Positives = 138/229 (60%), Gaps = 11/229 (4%)
Query: 244 EIDRTDIVMKHKLGGGQYGDVYEAAWK---RGNITVAVKTLKDD--TMALKDFLEEASIM 298
EID + + ++ +G G++G+V K + VA+KTLK ++FL EASIM
Sbjct: 608 EIDVSYVKIEEVIGAGEFGEVCRGRLKAPGKKESCVAIKTLKGGYTERQRREFLSEASIM 667
Query: 299 KEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIAS 358
+ HPN+++L GV T P I+TEFM G L +LR + + L+ M IAS
Sbjct: 668 GQFEHPNIIRLEGVVTNSMPVMILTEFMENGALDSFLRLNDGQFT--VIQLVGMLRGIAS 725
Query: 359 GMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMR----DDTYTAHAGAKFPIKW 414
GM YL S++HRDLAARN LV N + KV+DFGL+R + D TYT+ G K PI+W
Sbjct: 726 GMRYLAEMSYVHRDLAARNILVNSNLVCKVSDFGLSRFLEENSSDPTYTSSLGGKIPIRW 785
Query: 415 TAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
TAPE +A+ F++ SD W++GI++WE+ ++G PY + DV + +E+
Sbjct: 786 TAPEAIAFRKFTSASDAWSYGIVMWEVMSFGERPYWDMSNQDVINAIEQ 834
>BC032229-1|AAH32229.1| 894|Homo sapiens AXL receptor tyrosine
kinase protein.
Length = 894
Score = 180 bits (437), Expect = 1e-44
Identities = 103/235 (43%), Positives = 145/235 (61%), Gaps = 17/235 (7%)
Query: 245 IDRTDIVMKHKLGGGQYGDVYEAAWKRGN--ITVAVKTLKDDTMA---LKDFLEEASIMK 299
+DR + + LG G++G V E + + + VAVKT+K L+DFL EA MK
Sbjct: 531 VDRHKVALGKTLGEGEFGAVMEGQLNQDDSILKVAVKTMKIAICTRSELEDFLSEAVCMK 590
Query: 300 EMRHPNLVQLLGVC----TRE--PPFYIITEFMSRGNL---LEYLRAGAREC-VPGAVVL 349
E HPN+++L+GVC RE P +I FM G+L L Y R G + +P +++
Sbjct: 591 EFDHPNVMRLIGVCFQGSERESFPAPVVILPFMKHGDLHSFLLYSRLGDQPVYLPTQMLV 650
Query: 350 MYMATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLAR-LMRDDTYTAHAGA 408
+MA IASGM YL ++ FIHRDLAARNC++ EN V VADFGL++ + D Y A
Sbjct: 651 KFMA-DIASGMEYLSTKRFIHRDLAARNCMLNENMSVCVADFGLSKKIYNGDYYRQGRIA 709
Query: 409 KFPIKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
K P+KW A E LA +++KSDVW+FG+ +WEIAT G +PYPGV+ +++Y L +
Sbjct: 710 KMPVKWIAIESLADRVYTSKSDVWSFGVTMWEIATRGQTPYPGVENSEIYDYLRR 764
>AF125808-1|AAF19762.1| 318|Homo sapiens ETS related
protein-neurotrophic receptor tyrosine kinase fusion
protein protein.
Length = 318
Score = 180 bits (437), Expect = 1e-44
Identities = 96/229 (41%), Positives = 137/229 (59%), Gaps = 20/229 (8%)
Query: 241 DHWEIDRTDIVMKHKLGGGQYGDV-----YEAAWKRGNITVAVKTLKDDTMAL-KDFLEE 294
D I R DIV+K +LG G +G V Y + + + VAVK LKD T+A KDF E
Sbjct: 22 DVQHIKRRDIVLKRELGEGAFGKVFLAECYNLSPTKDKMLVAVKALKDPTLAARKDFQRE 81
Query: 295 ASIMKEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECV------P---- 344
A ++ ++H ++V+ GVC P ++ E+M G+L ++LRA + + P
Sbjct: 82 AELLTNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHGPDAMILVDGQPRQAK 141
Query: 345 ---GAVVLMYMATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLAR-LMRDD 400
G ++++A+QIASGM YL S+ F+HRDLA RNCLVG N LVK+ DFG++R + D
Sbjct: 142 GELGLSQMLHIASQIASGMVYLASQHFVHRDLATRNCLVGANLLVKIGDFGMSRDVYSTD 201
Query: 401 TYTAHAGAKFPIKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPY 449
Y PI+W PE + Y F+T+SDVW+FG++LWEI TYG P+
Sbjct: 202 YYRVGGHTMLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFTYGKQPW 250
>M76125-1|AAA61243.1| 885|Homo sapiens tyrosine kinase receptor
protein.
Length = 885
Score = 179 bits (436), Expect = 2e-44
Identities = 103/235 (43%), Positives = 145/235 (61%), Gaps = 17/235 (7%)
Query: 245 IDRTDIVMKHKLGGGQYGDVYEAAWKRGN--ITVAVKTLKDDTMA---LKDFLEEASIMK 299
+DR + + LG G++G V E + + + VAVKT+K L+DFL EA MK
Sbjct: 522 VDRHKVALGKTLGEGEFGAVMEGQLNQDDSILKVAVKTMKIAICTRSELEDFLSEAVCMK 581
Query: 300 EMRHPNLVQLLGVC----TRE--PPFYIITEFMSRGNL---LEYLRAGAREC-VPGAVVL 349
E HPN+++L+GVC RE P +I FM G+L L Y R G + +P +++
Sbjct: 582 EFDHPNVMRLIGVCFQGSERESFPAPVVILPFMKHGDLHSFLLYSRLGDQPVYLPTQMLV 641
Query: 350 MYMATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLAR-LMRDDTYTAHAGA 408
+MA IASGM YL ++ FIHRDLAARNC++ EN V VADFGL++ + D Y A
Sbjct: 642 KFMA-DIASGMEYLSTKRFIHRDLAARNCMLNENMSVCVADFGLSKKIYNGDYYRQGRIA 700
Query: 409 KFPIKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
K P+KW A E LA +++KSDVW+FG+ +WEIAT G +PYPGV+ +++Y L +
Sbjct: 701 KMPVKWIAIESLADRVYTSKSDVWSFGVTMWEIATRGQTPYPGVENSEIYDYLRQ 755
>AK222718-1|BAD96438.1| 820|Homo sapiens fibroblast growth factor
receptor 1 isoform 2 precursor variant protein.
Length = 820
Score = 179 bits (436), Expect = 2e-44
Identities = 104/253 (41%), Positives = 146/253 (57%), Gaps = 24/253 (9%)
Query: 235 FPLAPPDHWEIDRTDIVMKHKLGGGQYGDVYEAAW------KRGNIT-VAVKTLKDDTMA 287
+ L WE+ R +V+ LG G +G V A K +T VAVK LK D
Sbjct: 461 YELPEDPRWELPRDRLVLGRPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATE 520
Query: 288 --LKDFLEEASIMKEM-RHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRA----GAR 340
L D + E +MK + +H N++ LLG CT++ P Y+I E+ S+GNL EYL+A G
Sbjct: 521 KDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQAWRPPGLE 580
Query: 341 ECVP---------GAVVLMYMATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADF 391
C + L+ A Q+A GM YL S+ IHRDLAARN LV E++++K+ADF
Sbjct: 581 YCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADF 640
Query: 392 GLAR-LMRDDTYTAHAGAKFPIKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYP 450
GLAR + D Y + P+KW APE L ++ +SDVW+FG+LLWEI T G SPYP
Sbjct: 641 GLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYP 700
Query: 451 GVDLADVYHMLEK 463
GV + +++ +L++
Sbjct: 701 GVPVEELFKLLKE 713
>Z71929-1|CAA96492.1| 821|Homo sapiens FGFR2 protein.
Length = 821
Score = 179 bits (435), Expect = 2e-44
Identities = 103/253 (40%), Positives = 146/253 (57%), Gaps = 24/253 (9%)
Query: 235 FPLAPPDHWEIDRTDIVMKHKLGGGQYGDVYEAAW-------KRGNITVAVKTLKDDTMA 287
+ L WE R + + LG G +G V A + +TVAVK LKDD
Sbjct: 466 YELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATE 525
Query: 288 --LKDFLEEASIMKEM-RHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRA----GAR 340
L D + E +MK + +H N++ LLG CT++ P Y+I E+ S+GNL EYLRA G
Sbjct: 526 KDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGME 585
Query: 341 EC-----VPGAVV----LMYMATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADF 391
VP + L+ Q+A GM YL S+ IHRDLAARN LV EN+++K+ADF
Sbjct: 586 YSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADF 645
Query: 392 GLARLMRD-DTYTAHAGAKFPIKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYP 450
GLAR + + D Y + P+KW APE L ++ +SDVW+FG+L+WEI T G SPYP
Sbjct: 646 GLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYP 705
Query: 451 GVDLADVYHMLEK 463
G+ + +++ +L++
Sbjct: 706 GIPVEELFKLLKE 718
>Y00665-1|CAA68679.1| 622|Homo sapiens tyrosine kinase protein.
Length = 622
Score = 179 bits (435), Expect = 2e-44
Identities = 104/253 (41%), Positives = 146/253 (57%), Gaps = 24/253 (9%)
Query: 235 FPLAPPDHWEIDRTDIVMKHKLGGGQYGDVYEAAW------KRGNIT-VAVKTLKDDTMA 287
+ L WE+ R +V+ LG G +G V A K +T VAVK LK D
Sbjct: 263 YELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATE 322
Query: 288 --LKDFLEEASIMKEM-RHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRA----GAR 340
L D + E +MK + +H N++ LLG CT++ P Y+I E+ S+GNL EYL+A G
Sbjct: 323 KDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLE 382
Query: 341 ECVP---------GAVVLMYMATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADF 391
C + L+ A Q+A GM YL S+ IHRDLAARN LV E++++K+ADF
Sbjct: 383 YCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADF 442
Query: 392 GLAR-LMRDDTYTAHAGAKFPIKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYP 450
GLAR + D Y + P+KW APE L ++ +SDVW+FG+LLWEI T G SPYP
Sbjct: 443 GLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYP 502
Query: 451 GVDLADVYHMLEK 463
GV + +++ +L++
Sbjct: 503 GVPVEELFKLLKE 515
>X66945-1|CAA47375.1| 822|Homo sapiens fibroblast growth factor
receptor protein.
Length = 822
Score = 179 bits (435), Expect = 2e-44
Identities = 104/253 (41%), Positives = 146/253 (57%), Gaps = 24/253 (9%)
Query: 235 FPLAPPDHWEIDRTDIVMKHKLGGGQYGDVYEAAW------KRGNIT-VAVKTLKDDTMA 287
+ L WE+ R +V+ LG G +G V A K +T VAVK LK D
Sbjct: 463 YELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATE 522
Query: 288 --LKDFLEEASIMKEM-RHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRA----GAR 340
L D + E +MK + +H N++ LLG CT++ P Y+I E+ S+GNL EYL+A G
Sbjct: 523 KDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLE 582
Query: 341 ECVP---------GAVVLMYMATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADF 391
C + L+ A Q+A GM YL S+ IHRDLAARN LV E++++K+ADF
Sbjct: 583 YCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADF 642
Query: 392 GLAR-LMRDDTYTAHAGAKFPIKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYP 450
GLAR + D Y + P+KW APE L ++ +SDVW+FG+LLWEI T G SPYP
Sbjct: 643 GLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYP 702
Query: 451 GVDLADVYHMLEK 463
GV + +++ +L++
Sbjct: 703 GVPVEELFKLLKE 715
>X57122-1|CAA40404.1| 731|Homo sapiens Fibroblast Growth Factor
Receptor, 2 Ig-Domain Form protein.
Length = 731
Score = 179 bits (435), Expect = 2e-44
Identities = 104/253 (41%), Positives = 146/253 (57%), Gaps = 24/253 (9%)
Query: 235 FPLAPPDHWEIDRTDIVMKHKLGGGQYGDVYEAAW------KRGNIT-VAVKTLKDDTMA 287
+ L WE+ R +V+ LG G +G V A K +T VAVK LK D
Sbjct: 372 YELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATE 431
Query: 288 --LKDFLEEASIMKEM-RHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRA----GAR 340
L D + E +MK + +H N++ LLG CT++ P Y+I E+ S+GNL EYL+A G
Sbjct: 432 KDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLE 491
Query: 341 ECVP---------GAVVLMYMATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADF 391
C + L+ A Q+A GM YL S+ IHRDLAARN LV E++++K+ADF
Sbjct: 492 YCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADF 551
Query: 392 GLAR-LMRDDTYTAHAGAKFPIKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYP 450
GLAR + D Y + P+KW APE L ++ +SDVW+FG+LLWEI T G SPYP
Sbjct: 552 GLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYP 611
Query: 451 GVDLADVYHMLEK 463
GV + +++ +L++
Sbjct: 612 GVPVEELFKLLKE 624
>X57121-1|CAA40403.1| 822|Homo sapiens Fibroblast Growth Factor
Receptor, 3-Ig Domain+2orm protein.
Length = 822
Score = 179 bits (435), Expect = 2e-44
Identities = 104/253 (41%), Positives = 146/253 (57%), Gaps = 24/253 (9%)
Query: 235 FPLAPPDHWEIDRTDIVMKHKLGGGQYGDVYEAAW------KRGNIT-VAVKTLKDDTMA 287
+ L WE+ R +V+ LG G +G V A K +T VAVK LK D
Sbjct: 463 YELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATE 522
Query: 288 --LKDFLEEASIMKEM-RHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRA----GAR 340
L D + E +MK + +H N++ LLG CT++ P Y+I E+ S+GNL EYL+A G
Sbjct: 523 KDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLE 582
Query: 341 ECVP---------GAVVLMYMATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADF 391
C + L+ A Q+A GM YL S+ IHRDLAARN LV E++++K+ADF
Sbjct: 583 YCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADF 642
Query: 392 GLAR-LMRDDTYTAHAGAKFPIKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYP 450
GLAR + D Y + P+KW APE L ++ +SDVW+FG+LLWEI T G SPYP
Sbjct: 643 GLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYP 702
Query: 451 GVDLADVYHMLEK 463
GV + +++ +L++
Sbjct: 703 GVPVEELFKLLKE 715
>X57120-1|CAA40402.1| 820|Homo sapiens Fibroblast Growth Factor
Receptor, 3 Ig-Domain Form protein.
Length = 820
Score = 179 bits (435), Expect = 2e-44
Identities = 104/253 (41%), Positives = 146/253 (57%), Gaps = 24/253 (9%)
Query: 235 FPLAPPDHWEIDRTDIVMKHKLGGGQYGDVYEAAW------KRGNIT-VAVKTLKDDTMA 287
+ L WE+ R +V+ LG G +G V A K +T VAVK LK D
Sbjct: 461 YELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATE 520
Query: 288 --LKDFLEEASIMKEM-RHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRA----GAR 340
L D + E +MK + +H N++ LLG CT++ P Y+I E+ S+GNL EYL+A G
Sbjct: 521 KDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLE 580
Query: 341 ECVP---------GAVVLMYMATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADF 391
C + L+ A Q+A GM YL S+ IHRDLAARN LV E++++K+ADF
Sbjct: 581 YCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADF 640
Query: 392 GLAR-LMRDDTYTAHAGAKFPIKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYP 450
GLAR + D Y + P+KW APE L ++ +SDVW+FG+LLWEI T G SPYP
Sbjct: 641 GLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYP 700
Query: 451 GVDLADVYHMLEK 463
GV + +++ +L++
Sbjct: 701 GVPVEELFKLLKE 713
>X57119-1|CAA40401.1| 733|Homo sapiens Fibroblast Growth Factor
Receptor, 2-Ig Domain+25-1 protein.
Length = 733
Score = 179 bits (435), Expect = 2e-44
Identities = 104/253 (41%), Positives = 146/253 (57%), Gaps = 24/253 (9%)
Query: 235 FPLAPPDHWEIDRTDIVMKHKLGGGQYGDVYEAAW------KRGNIT-VAVKTLKDDTMA 287
+ L WE+ R +V+ LG G +G V A K +T VAVK LK D
Sbjct: 374 YELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATE 433
Query: 288 --LKDFLEEASIMKEM-RHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRA----GAR 340
L D + E +MK + +H N++ LLG CT++ P Y+I E+ S+GNL EYL+A G
Sbjct: 434 KDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLE 493
Query: 341 ECVP---------GAVVLMYMATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADF 391
C + L+ A Q+A GM YL S+ IHRDLAARN LV E++++K+ADF
Sbjct: 494 YCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADF 553
Query: 392 GLAR-LMRDDTYTAHAGAKFPIKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYP 450
GLAR + D Y + P+KW APE L ++ +SDVW+FG+LLWEI T G SPYP
Sbjct: 554 GLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYP 613
Query: 451 GVDLADVYHMLEK 463
GV + +++ +L++
Sbjct: 614 GVPVEELFKLLKE 626
>X56191-1|CAA39654.1| 769|Homo sapiens fibroblast growth factor
(FGR) receptor protein.
Length = 769
Score = 179 bits (435), Expect = 2e-44
Identities = 103/253 (40%), Positives = 146/253 (57%), Gaps = 24/253 (9%)
Query: 235 FPLAPPDHWEIDRTDIVMKHKLGGGQYGDVYEAAW-------KRGNITVAVKTLKDDTMA 287
+ L WE R + + LG G +G V A + +TVAVK LKDD
Sbjct: 467 YELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATE 526
Query: 288 --LKDFLEEASIMKEM-RHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRA----GAR 340
L D + E +MK + +H N++ LLG CT++ P Y+I E+ S+GNL EYLRA G
Sbjct: 527 KDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGME 586
Query: 341 EC-----VPGAVV----LMYMATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADF 391
VP + L+ Q+A GM YL S+ IHRDLAARN LV EN+++K+ADF
Sbjct: 587 YSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADF 646
Query: 392 GLARLMRD-DTYTAHAGAKFPIKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYP 450
GLAR + + D Y + P+KW APE L ++ +SDVW+FG+L+WEI T G SPYP
Sbjct: 647 GLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYP 706
Query: 451 GVDLADVYHMLEK 463
G+ + +++ +L++
Sbjct: 707 GIPVEELFKLLKE 719
>X52833-1|CAA37015.1| 822|Homo sapiens protein ( Human flg mRNA for
fibroblast growth factor receptor-FLG. ).
Length = 822
Score = 179 bits (435), Expect = 2e-44
Identities = 104/253 (41%), Positives = 146/253 (57%), Gaps = 24/253 (9%)
Query: 235 FPLAPPDHWEIDRTDIVMKHKLGGGQYGDVYEAAW------KRGNIT-VAVKTLKDDTMA 287
+ L WE+ R +V+ LG G +G V A K +T VAVK LK D
Sbjct: 463 YELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATE 522
Query: 288 --LKDFLEEASIMKEM-RHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRA----GAR 340
L D + E +MK + +H N++ LLG CT++ P Y+I E+ S+GNL EYL+A G
Sbjct: 523 KDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLE 582
Query: 341 ECVP---------GAVVLMYMATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADF 391
C + L+ A Q+A GM YL S+ IHRDLAARN LV E++++K+ADF
Sbjct: 583 YCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADF 642
Query: 392 GLAR-LMRDDTYTAHAGAKFPIKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYP 450
GLAR + D Y + P+KW APE L ++ +SDVW+FG+LLWEI T G SPYP
Sbjct: 643 GLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYP 702
Query: 451 GVDLADVYHMLEK 463
GV + +++ +L++
Sbjct: 703 GVPVEELFKLLKE 715
>X52832-1|CAA37014.1| 821|Homo sapiens protein ( Human bek mRNA for
fibroblast growth factor receptor-BEK. ).
Length = 821
Score = 179 bits (435), Expect = 2e-44
Identities = 103/253 (40%), Positives = 146/253 (57%), Gaps = 24/253 (9%)
Query: 235 FPLAPPDHWEIDRTDIVMKHKLGGGQYGDVYEAAW-------KRGNITVAVKTLKDDTMA 287
+ L WE R + + LG G +G V A + +TVAVK LKDD
Sbjct: 466 YELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATE 525
Query: 288 --LKDFLEEASIMKEM-RHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRA----GAR 340
L D + E +MK + +H N++ LLG CT++ P Y+I E+ S+GNL EYLRA G
Sbjct: 526 KDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGME 585
Query: 341 EC-----VPGAVV----LMYMATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADF 391
VP + L+ Q+A GM YL S+ IHRDLAARN LV EN+++K+ADF
Sbjct: 586 YSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADF 645
Query: 392 GLARLMRD-DTYTAHAGAKFPIKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYP 450
GLAR + + D Y + P+KW APE L ++ +SDVW+FG+L+WEI T G SPYP
Sbjct: 646 GLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYP 705
Query: 451 GVDLADVYHMLEK 463
G+ + +++ +L++
Sbjct: 706 GIPVEELFKLLKE 718
>X51803-1|CAA36101.1| 822|Homo sapiens protein ( Human mRNA for
fibroblast growth factor (FGF) receptor. ).
Length = 822
Score = 179 bits (435), Expect = 2e-44
Identities = 104/253 (41%), Positives = 146/253 (57%), Gaps = 24/253 (9%)
Query: 235 FPLAPPDHWEIDRTDIVMKHKLGGGQYGDVYEAAW------KRGNIT-VAVKTLKDDTMA 287
+ L WE+ R +V+ LG G +G V A K +T VAVK LK D
Sbjct: 463 YELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATE 522
Query: 288 --LKDFLEEASIMKEM-RHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRA----GAR 340
L D + E +MK + +H N++ LLG CT++ P Y+I E+ S+GNL EYL+A G
Sbjct: 523 KDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLE 582
Query: 341 ECVP---------GAVVLMYMATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADF 391
C + L+ A Q+A GM YL S+ IHRDLAARN LV E++++K+ADF
Sbjct: 583 YCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADF 642
Query: 392 GLAR-LMRDDTYTAHAGAKFPIKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYP 450
GLAR + D Y + P+KW APE L ++ +SDVW+FG+LLWEI T G SPYP
Sbjct: 643 GLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYP 702
Query: 451 GVDLADVYHMLEK 463
GV + +++ +L++
Sbjct: 703 GVPVEELFKLLKE 715
>M97193-1|AAA52449.1| 822|Homo sapiens fibroblast growth factor
receptor 2 protein.
Length = 822
Score = 179 bits (435), Expect = 2e-44
Identities = 103/253 (40%), Positives = 146/253 (57%), Gaps = 24/253 (9%)
Query: 235 FPLAPPDHWEIDRTDIVMKHKLGGGQYGDVYEAAW-------KRGNITVAVKTLKDDTMA 287
+ L WE R + + LG G +G V A + +TVAVK LKDD
Sbjct: 467 YELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATE 526
Query: 288 --LKDFLEEASIMKEM-RHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRA----GAR 340
L D + E +MK + +H N++ LLG CT++ P Y+I E+ S+GNL EYLRA G
Sbjct: 527 KDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGME 586
Query: 341 EC-----VPGAVV----LMYMATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADF 391
VP + L+ Q+A GM YL S+ IHRDLAARN LV EN+++K+ADF
Sbjct: 587 YSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADF 646
Query: 392 GLARLMRD-DTYTAHAGAKFPIKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYP 450
GLAR + + D Y + P+KW APE L ++ +SDVW+FG+L+WEI T G SPYP
Sbjct: 647 GLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYP 706
Query: 451 GVDLADVYHMLEK 463
G+ + +++ +L++
Sbjct: 707 GIPVEELFKLLKE 719
>M87771-1|AAA59471.1| 705|Homo sapiens fibroblast growth factor
receptor protein.
Length = 705
Score = 179 bits (435), Expect = 2e-44
Identities = 103/253 (40%), Positives = 146/253 (57%), Gaps = 24/253 (9%)
Query: 235 FPLAPPDHWEIDRTDIVMKHKLGGGQYGDVYEAAW-------KRGNITVAVKTLKDDTMA 287
+ L WE R + + LG G +G V A + +TVAVK LKDD
Sbjct: 350 YELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATE 409
Query: 288 --LKDFLEEASIMKEM-RHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRA----GAR 340
L D + E +MK + +H N++ LLG CT++ P Y+I E+ S+GNL EYLRA G
Sbjct: 410 KDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGME 469
Query: 341 EC-----VPGAVV----LMYMATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADF 391
VP + L+ Q+A GM YL S+ IHRDLAARN LV EN+++K+ADF
Sbjct: 470 YSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADF 529
Query: 392 GLARLMRD-DTYTAHAGAKFPIKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYP 450
GLAR + + D Y + P+KW APE L ++ +SDVW+FG+L+WEI T G SPYP
Sbjct: 530 GLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYP 589
Query: 451 GVDLADVYHMLEK 463
G+ + +++ +L++
Sbjct: 590 GIPVEELFKLLKE 602
>M87770-1|AAA59470.1| 821|Homo sapiens fibroblast growth factor
receptor protein.
Length = 821
Score = 179 bits (435), Expect = 2e-44
Identities = 103/253 (40%), Positives = 146/253 (57%), Gaps = 24/253 (9%)
Query: 235 FPLAPPDHWEIDRTDIVMKHKLGGGQYGDVYEAAW-------KRGNITVAVKTLKDDTMA 287
+ L WE R + + LG G +G V A + +TVAVK LKDD
Sbjct: 466 YELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATE 525
Query: 288 --LKDFLEEASIMKEM-RHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRA----GAR 340
L D + E +MK + +H N++ LLG CT++ P Y+I E+ S+GNL EYLRA G
Sbjct: 526 KDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGME 585
Query: 341 EC-----VPGAVV----LMYMATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADF 391
VP + L+ Q+A GM YL S+ IHRDLAARN LV EN+++K+ADF
Sbjct: 586 YSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADF 645
Query: 392 GLARLMRD-DTYTAHAGAKFPIKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYP 450
GLAR + + D Y + P+KW APE L ++ +SDVW+FG+L+WEI T G SPYP
Sbjct: 646 GLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYP 705
Query: 451 GVDLADVYHMLEK 463
G+ + +++ +L++
Sbjct: 706 GIPVEELFKLLKE 718
>M63887-1|AAA35958.1| 822|Homo sapiens heparin-binding growth
factor receptor protein.
Length = 822
Score = 179 bits (435), Expect = 2e-44
Identities = 104/253 (41%), Positives = 146/253 (57%), Gaps = 24/253 (9%)
Query: 235 FPLAPPDHWEIDRTDIVMKHKLGGGQYGDVYEAAW------KRGNIT-VAVKTLKDDTMA 287
+ L WE+ R +V+ LG G +G V A K +T VAVK LK D
Sbjct: 463 YELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATE 522
Query: 288 --LKDFLEEASIMKEM-RHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRA----GAR 340
L D + E +MK + +H N++ LLG CT++ P Y+I E+ S+GNL EYL+A G
Sbjct: 523 KDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLE 582
Query: 341 ECVP---------GAVVLMYMATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADF 391
C + L+ A Q+A GM YL S+ IHRDLAARN LV E++++K+ADF
Sbjct: 583 YCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADF 642
Query: 392 GLAR-LMRDDTYTAHAGAKFPIKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYP 450
GLAR + D Y + P+KW APE L ++ +SDVW+FG+LLWEI T G SPYP
Sbjct: 643 GLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYP 702
Query: 451 GVDLADVYHMLEK 463
GV + +++ +L++
Sbjct: 703 GVPVEELFKLLKE 715
>M60485-1|AAA35840.1| 820|Homo sapiens fibroblast growth factor
receptor protein.
Length = 820
Score = 179 bits (435), Expect = 2e-44
Identities = 104/253 (41%), Positives = 146/253 (57%), Gaps = 24/253 (9%)
Query: 235 FPLAPPDHWEIDRTDIVMKHKLGGGQYGDVYEAAW------KRGNIT-VAVKTLKDDTMA 287
+ L WE+ R +V+ LG G +G V A K +T VAVK LK D
Sbjct: 461 YELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATE 520
Query: 288 --LKDFLEEASIMKEM-RHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRA----GAR 340
L D + E +MK + +H N++ LLG CT++ P Y+I E+ S+GNL EYL+A G
Sbjct: 521 KDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLE 580
Query: 341 ECVP---------GAVVLMYMATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADF 391
C + L+ A Q+A GM YL S+ IHRDLAARN LV E++++K+ADF
Sbjct: 581 YCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADF 640
Query: 392 GLAR-LMRDDTYTAHAGAKFPIKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYP 450
GLAR + D Y + P+KW APE L ++ +SDVW+FG+LLWEI T G SPYP
Sbjct: 641 GLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYP 700
Query: 451 GVDLADVYHMLEK 463
GV + +++ +L++
Sbjct: 701 GVPVEELFKLLKE 713
>M55614-1|AAA61188.1| 822|Homo sapiens TK14 protein protein.
Length = 822
Score = 179 bits (435), Expect = 2e-44
Identities = 103/253 (40%), Positives = 146/253 (57%), Gaps = 24/253 (9%)
Query: 235 FPLAPPDHWEIDRTDIVMKHKLGGGQYGDVYEAAW-------KRGNITVAVKTLKDDTMA 287
+ L WE R + + LG G +G V A + +TVAVK LKDD
Sbjct: 467 YELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATE 526
Query: 288 --LKDFLEEASIMKEM-RHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRA----GAR 340
L D + E +MK + +H N++ LLG CT++ P Y+I E+ S+GNL EYLRA G
Sbjct: 527 KDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGME 586
Query: 341 EC-----VPGAVV----LMYMATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADF 391
VP + L+ Q+A GM YL S+ IHRDLAARN LV EN+++K+ADF
Sbjct: 587 YSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADF 646
Query: 392 GLARLMRD-DTYTAHAGAKFPIKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYP 450
GLAR + + D Y + P+KW APE L ++ +SDVW+FG+L+WEI T G SPYP
Sbjct: 647 GLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYP 706
Query: 451 GVDLADVYHMLEK 463
G+ + +++ +L++
Sbjct: 707 GIPVEELFKLLKE 719
>M35718-1|AAA36152.1| 682|Homo sapiens protein ( Human
heparin-binding growth factor receptor K-sam mRNA. ).
Length = 682
Score = 179 bits (435), Expect = 2e-44
Identities = 103/253 (40%), Positives = 146/253 (57%), Gaps = 24/253 (9%)
Query: 235 FPLAPPDHWEIDRTDIVMKHKLGGGQYGDVYEAAW-------KRGNITVAVKTLKDDTMA 287
+ L WE R + + LG G +G V A + +TVAVK LKDD
Sbjct: 376 YELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATE 435
Query: 288 --LKDFLEEASIMKEM-RHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRA----GAR 340
L D + E +MK + +H N++ LLG CT++ P Y+I E+ S+GNL EYLRA G
Sbjct: 436 KDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGME 495
Query: 341 EC-----VPGAVV----LMYMATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADF 391
VP + L+ Q+A GM YL S+ IHRDLAARN LV EN+++K+ADF
Sbjct: 496 YSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADF 555
Query: 392 GLARLMRD-DTYTAHAGAKFPIKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYP 450
GLAR + + D Y + P+KW APE L ++ +SDVW+FG+L+WEI T G SPYP
Sbjct: 556 GLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYP 615
Query: 451 GVDLADVYHMLEK 463
G+ + +++ +L++
Sbjct: 616 GIPVEELFKLLKE 628
>M34641-1|AAA35835.1| 820|Homo sapiens protein ( Human fibroblast
growth factor (FGF) receptor-1 mRNA, complete cds. ).
Length = 820
Score = 179 bits (435), Expect = 2e-44
Identities = 104/253 (41%), Positives = 146/253 (57%), Gaps = 24/253 (9%)
Query: 235 FPLAPPDHWEIDRTDIVMKHKLGGGQYGDVYEAAW------KRGNIT-VAVKTLKDDTMA 287
+ L WE+ R +V+ LG G +G V A K +T VAVK LK D
Sbjct: 461 YELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATE 520
Query: 288 --LKDFLEEASIMKEM-RHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRA----GAR 340
L D + E +MK + +H N++ LLG CT++ P Y+I E+ S+GNL EYL+A G
Sbjct: 521 KDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLE 580
Query: 341 ECVP---------GAVVLMYMATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADF 391
C + L+ A Q+A GM YL S+ IHRDLAARN LV E++++K+ADF
Sbjct: 581 YCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADF 640
Query: 392 GLAR-LMRDDTYTAHAGAKFPIKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYP 450
GLAR + D Y + P+KW APE L ++ +SDVW+FG+LLWEI T G SPYP
Sbjct: 641 GLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYP 700
Query: 451 GVDLADVYHMLEK 463
GV + +++ +L++
Sbjct: 701 GVPVEELFKLLKE 713
>M34186-1|AAA35837.1| 731|Homo sapiens protein ( Human fibroblast
growth factor receptor (FGFr) transmembrane form mRNA,
complete cds. ).
Length = 731
Score = 179 bits (435), Expect = 2e-44
Identities = 104/253 (41%), Positives = 146/253 (57%), Gaps = 24/253 (9%)
Query: 235 FPLAPPDHWEIDRTDIVMKHKLGGGQYGDVYEAAW------KRGNIT-VAVKTLKDDTMA 287
+ L WE+ R +V+ LG G +G V A K +T VAVK LK D
Sbjct: 372 YELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATE 431
Query: 288 --LKDFLEEASIMKEM-RHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRA----GAR 340
L D + E +MK + +H N++ LLG CT++ P Y+I E+ S+GNL EYL+A G
Sbjct: 432 KDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLE 491
Query: 341 ECVP---------GAVVLMYMATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADF 391
C + L+ A Q+A GM YL S+ IHRDLAARN LV E++++K+ADF
Sbjct: 492 YCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADF 551
Query: 392 GLAR-LMRDDTYTAHAGAKFPIKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYP 450
GLAR + D Y + P+KW APE L ++ +SDVW+FG+LLWEI T G SPYP
Sbjct: 552 GLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYP 611
Query: 451 GVDLADVYHMLEK 463
GV + +++ +L++
Sbjct: 612 GVPVEELFKLLKE 624
>M34185-1|AAA35836.1| 733|Homo sapiens protein ( Human fibroblast
growth factor receptor (FGFr) transmembrane form mRNA,
complete cds. ).
Length = 733
Score = 179 bits (435), Expect = 2e-44
Identities = 104/253 (41%), Positives = 146/253 (57%), Gaps = 24/253 (9%)
Query: 235 FPLAPPDHWEIDRTDIVMKHKLGGGQYGDVYEAAW------KRGNIT-VAVKTLKDDTMA 287
+ L WE+ R +V+ LG G +G V A K +T VAVK LK D
Sbjct: 374 YELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATE 433
Query: 288 --LKDFLEEASIMKEM-RHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRA----GAR 340
L D + E +MK + +H N++ LLG CT++ P Y+I E+ S+GNL EYL+A G
Sbjct: 434 KDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLE 493
Query: 341 ECVP---------GAVVLMYMATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADF 391
C + L+ A Q+A GM YL S+ IHRDLAARN LV E++++K+ADF
Sbjct: 494 YCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADF 553
Query: 392 GLAR-LMRDDTYTAHAGAKFPIKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYP 450
GLAR + D Y + P+KW APE L ++ +SDVW+FG+LLWEI T G SPYP
Sbjct: 554 GLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYP 613
Query: 451 GVDLADVYHMLEK 463
GV + +++ +L++
Sbjct: 614 GVPVEELFKLLKE 626
>DQ493927-1|ABE96832.1| 785|Homo sapiens fibroblast growth factor
receptor 2 (bacteria-expressed kinase, keratinocyte gr
protein.
Length = 785
Score = 179 bits (435), Expect = 2e-44
Identities = 103/253 (40%), Positives = 146/253 (57%), Gaps = 24/253 (9%)
Query: 235 FPLAPPDHWEIDRTDIVMKHKLGGGQYGDVYEAAW-------KRGNITVAVKTLKDDTMA 287
+ L WE R + + LG G +G V A + +TVAVK LKDD
Sbjct: 464 YELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATE 523
Query: 288 --LKDFLEEASIMKEM-RHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRA----GAR 340
L D + E +MK + +H N++ LLG CT++ P Y+I E+ S+GNL EYLRA G
Sbjct: 524 KDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGME 583
Query: 341 EC-----VPGAVV----LMYMATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADF 391
VP + L+ Q+A GM YL S+ IHRDLAARN LV EN+++K+ADF
Sbjct: 584 YSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADF 643
Query: 392 GLARLMRD-DTYTAHAGAKFPIKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYP 450
GLAR + + D Y + P+KW APE L ++ +SDVW+FG+L+WEI T G SPYP
Sbjct: 644 GLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYP 703
Query: 451 GVDLADVYHMLEK 463
G+ + +++ +L++
Sbjct: 704 GIPVEELFKLLKE 716
>BC091494-1|AAH91494.1| 731|Homo sapiens fibroblast growth factor
receptor 1 (fms-related tyrosine kinase 2, Pfeiffer sy
protein.
Length = 731
Score = 179 bits (435), Expect = 2e-44
Identities = 104/253 (41%), Positives = 146/253 (57%), Gaps = 24/253 (9%)
Query: 235 FPLAPPDHWEIDRTDIVMKHKLGGGQYGDVYEAAW------KRGNIT-VAVKTLKDDTMA 287
+ L WE+ R +V+ LG G +G V A K +T VAVK LK D
Sbjct: 372 YELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATE 431
Query: 288 --LKDFLEEASIMKEM-RHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRA----GAR 340
L D + E +MK + +H N++ LLG CT++ P Y+I E+ S+GNL EYL+A G
Sbjct: 432 KDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLE 491
Query: 341 ECVP---------GAVVLMYMATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADF 391
C + L+ A Q+A GM YL S+ IHRDLAARN LV E++++K+ADF
Sbjct: 492 YCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADF 551
Query: 392 GLAR-LMRDDTYTAHAGAKFPIKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYP 450
GLAR + D Y + P+KW APE L ++ +SDVW+FG+LLWEI T G SPYP
Sbjct: 552 GLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYP 611
Query: 451 GVDLADVYHMLEK 463
GV + +++ +L++
Sbjct: 612 GVPVEELFKLLKE 624
>BC039243-1|AAH39243.2| 704|Homo sapiens FGFR2 protein protein.
Length = 704
Score = 179 bits (435), Expect = 2e-44
Identities = 103/253 (40%), Positives = 146/253 (57%), Gaps = 24/253 (9%)
Query: 235 FPLAPPDHWEIDRTDIVMKHKLGGGQYGDVYEAAW-------KRGNITVAVKTLKDDTMA 287
+ L WE R + + LG G +G V A + +TVAVK LKDD
Sbjct: 349 YELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATE 408
Query: 288 --LKDFLEEASIMKEM-RHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRA----GAR 340
L D + E +MK + +H N++ LLG CT++ P Y+I E+ S+GNL EYLRA G
Sbjct: 409 KDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGME 468
Query: 341 EC-----VPGAVV----LMYMATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADF 391
VP + L+ Q+A GM YL S+ IHRDLAARN LV EN+++K+ADF
Sbjct: 469 YSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADF 528
Query: 392 GLARLMRD-DTYTAHAGAKFPIKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYP 450
GLAR + + D Y + P+KW APE L ++ +SDVW+FG+L+WEI T G SPYP
Sbjct: 529 GLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYP 588
Query: 451 GVDLADVYHMLEK 463
G+ + +++ +L++
Sbjct: 589 GIPVEELFKLLKE 601
>BC018128-1|AAH18128.1| 820|Homo sapiens fibroblast growth factor
receptor 1 (fms-related tyrosine kinase 2, Pfeiffer sy
protein.
Length = 820
Score = 179 bits (435), Expect = 2e-44
Identities = 104/253 (41%), Positives = 146/253 (57%), Gaps = 24/253 (9%)
Query: 235 FPLAPPDHWEIDRTDIVMKHKLGGGQYGDVYEAAW------KRGNIT-VAVKTLKDDTMA 287
+ L WE+ R +V+ LG G +G V A K +T VAVK LK D
Sbjct: 461 YELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATE 520
Query: 288 --LKDFLEEASIMKEM-RHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRA----GAR 340
L D + E +MK + +H N++ LLG CT++ P Y+I E+ S+GNL EYL+A G
Sbjct: 521 KDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLE 580
Query: 341 ECVP---------GAVVLMYMATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADF 391
C + L+ A Q+A GM YL S+ IHRDLAARN LV E++++K+ADF
Sbjct: 581 YCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADF 640
Query: 392 GLAR-LMRDDTYTAHAGAKFPIKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYP 450
GLAR + D Y + P+KW APE L ++ +SDVW+FG+LLWEI T G SPYP
Sbjct: 641 GLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYP 700
Query: 451 GVDLADVYHMLEK 463
GV + +++ +L++
Sbjct: 701 GVPVEELFKLLKE 713
>BC015035-1|AAH15035.1| 820|Homo sapiens FGFR1 protein protein.
Length = 820
Score = 179 bits (435), Expect = 2e-44
Identities = 104/253 (41%), Positives = 146/253 (57%), Gaps = 24/253 (9%)
Query: 235 FPLAPPDHWEIDRTDIVMKHKLGGGQYGDVYEAAW------KRGNIT-VAVKTLKDDTMA 287
+ L WE+ R +V+ LG G +G V A K +T VAVK LK D
Sbjct: 461 YELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATE 520
Query: 288 --LKDFLEEASIMKEM-RHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRA----GAR 340
L D + E +MK + +H N++ LLG CT++ P Y+I E+ S+GNL EYL+A G
Sbjct: 521 KDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLE 580
Query: 341 ECVP---------GAVVLMYMATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADF 391
C + L+ A Q+A GM YL S+ IHRDLAARN LV E++++K+ADF
Sbjct: 581 YCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADF 640
Query: 392 GLAR-LMRDDTYTAHAGAKFPIKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYP 450
GLAR + D Y + P+KW APE L ++ +SDVW+FG+LLWEI T G SPYP
Sbjct: 641 GLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYP 700
Query: 451 GVDLADVYHMLEK 463
GV + +++ +L++
Sbjct: 701 GVPVEELFKLLKE 713
>AY585209-1|AAS79322.1| 822|Homo sapiens fibroblast growth factor
receptor 1 (fms-related tyrosine kinase 2, Pfeiffer sy
protein.
Length = 822
Score = 179 bits (435), Expect = 2e-44
Identities = 104/253 (41%), Positives = 146/253 (57%), Gaps = 24/253 (9%)
Query: 235 FPLAPPDHWEIDRTDIVMKHKLGGGQYGDVYEAAW------KRGNIT-VAVKTLKDDTMA 287
+ L WE+ R +V+ LG G +G V A K +T VAVK LK D
Sbjct: 463 YELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATE 522
Query: 288 --LKDFLEEASIMKEM-RHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRA----GAR 340
L D + E +MK + +H N++ LLG CT++ P Y+I E+ S+GNL EYL+A G
Sbjct: 523 KDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLE 582
Query: 341 ECVP---------GAVVLMYMATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADF 391
C + L+ A Q+A GM YL S+ IHRDLAARN LV E++++K+ADF
Sbjct: 583 YCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADF 642
Query: 392 GLAR-LMRDDTYTAHAGAKFPIKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYP 450
GLAR + D Y + P+KW APE L ++ +SDVW+FG+LLWEI T G SPYP
Sbjct: 643 GLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYP 702
Query: 451 GVDLADVYHMLEK 463
GV + +++ +L++
Sbjct: 703 GVPVEELFKLLKE 715
>AF487553-1|AAM74056.1| 822|Homo sapiens fibroblast growth factor
receptor 2 protein.
Length = 822
Score = 179 bits (435), Expect = 2e-44
Identities = 103/253 (40%), Positives = 146/253 (57%), Gaps = 24/253 (9%)
Query: 235 FPLAPPDHWEIDRTDIVMKHKLGGGQYGDVYEAAW-------KRGNITVAVKTLKDDTMA 287
+ L WE R + + LG G +G V A + +TVAVK LKDD
Sbjct: 467 YELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATE 526
Query: 288 --LKDFLEEASIMKEM-RHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRA----GAR 340
L D + E +MK + +H N++ LLG CT++ P Y+I E+ S+GNL EYLRA G
Sbjct: 527 KDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGME 586
Query: 341 EC-----VPGAVV----LMYMATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADF 391
VP + L+ Q+A GM YL S+ IHRDLAARN LV EN+++K+ADF
Sbjct: 587 YSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADF 646
Query: 392 GLARLMRD-DTYTAHAGAKFPIKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYP 450
GLAR + + D Y + P+KW APE L ++ +SDVW+FG+L+WEI T G SPYP
Sbjct: 647 GLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYP 706
Query: 451 GVDLADVYHMLEK 463
G+ + +++ +L++
Sbjct: 707 GIPVEELFKLLKE 719
>AF360695-4|AAK94208.1| 766|Homo sapiens keratinocyte growth factor
receptor 2 isoform K-sam-IIC3 protein.
Length = 766
Score = 179 bits (435), Expect = 2e-44
Identities = 103/253 (40%), Positives = 146/253 (57%), Gaps = 24/253 (9%)
Query: 235 FPLAPPDHWEIDRTDIVMKHKLGGGQYGDVYEAAW-------KRGNITVAVKTLKDDTMA 287
+ L WE R + + LG G +G V A + +TVAVK LKDD
Sbjct: 464 YELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATE 523
Query: 288 --LKDFLEEASIMKEM-RHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRA----GAR 340
L D + E +MK + +H N++ LLG CT++ P Y+I E+ S+GNL EYLRA G
Sbjct: 524 KDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGME 583
Query: 341 EC-----VPGAVV----LMYMATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADF 391
VP + L+ Q+A GM YL S+ IHRDLAARN LV EN+++K+ADF
Sbjct: 584 YSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADF 643
Query: 392 GLARLMRD-DTYTAHAGAKFPIKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYP 450
GLAR + + D Y + P+KW APE L ++ +SDVW+FG+L+WEI T G SPYP
Sbjct: 644 GLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYP 703
Query: 451 GVDLADVYHMLEK 463
G+ + +++ +L++
Sbjct: 704 GIPVEELFKLLKE 716
>AF360695-3|AAK94209.1| 785|Homo sapiens keratinocyte growth factor
receptor 2 isoform K-sam-IIC2 protein.
Length = 785
Score = 179 bits (435), Expect = 2e-44
Identities = 103/253 (40%), Positives = 146/253 (57%), Gaps = 24/253 (9%)
Query: 235 FPLAPPDHWEIDRTDIVMKHKLGGGQYGDVYEAAW-------KRGNITVAVKTLKDDTMA 287
+ L WE R + + LG G +G V A + +TVAVK LKDD
Sbjct: 464 YELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATE 523
Query: 288 --LKDFLEEASIMKEM-RHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRA----GAR 340
L D + E +MK + +H N++ LLG CT++ P Y+I E+ S+GNL EYLRA G
Sbjct: 524 KDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGME 583
Query: 341 EC-----VPGAVV----LMYMATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADF 391
VP + L+ Q+A GM YL S+ IHRDLAARN LV EN+++K+ADF
Sbjct: 584 YSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADF 643
Query: 392 GLARLMRD-DTYTAHAGAKFPIKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYP 450
GLAR + + D Y + P+KW APE L ++ +SDVW+FG+L+WEI T G SPYP
Sbjct: 644 GLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYP 703
Query: 451 GVDLADVYHMLEK 463
G+ + +++ +L++
Sbjct: 704 GIPVEELFKLLKE 716
>AF360695-2|AAK94205.1| 819|Homo sapiens keratinocyte growth factor
receptor 2 isoform BEK protein.
Length = 819
Score = 179 bits (435), Expect = 2e-44
Identities = 103/253 (40%), Positives = 146/253 (57%), Gaps = 24/253 (9%)
Query: 235 FPLAPPDHWEIDRTDIVMKHKLGGGQYGDVYEAAW-------KRGNITVAVKTLKDDTMA 287
+ L WE R + + LG G +G V A + +TVAVK LKDD
Sbjct: 464 YELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATE 523
Query: 288 --LKDFLEEASIMKEM-RHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRA----GAR 340
L D + E +MK + +H N++ LLG CT++ P Y+I E+ S+GNL EYLRA G
Sbjct: 524 KDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGME 583
Query: 341 EC-----VPGAVV----LMYMATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADF 391
VP + L+ Q+A GM YL S+ IHRDLAARN LV EN+++K+ADF
Sbjct: 584 YSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADF 643
Query: 392 GLARLMRD-DTYTAHAGAKFPIKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYP 450
GLAR + + D Y + P+KW APE L ++ +SDVW+FG+L+WEI T G SPYP
Sbjct: 644 GLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYP 703
Query: 451 GVDLADVYHMLEK 463
G+ + +++ +L++
Sbjct: 704 GIPVEELFKLLKE 716
>AF360695-1|AAK94206.1| 820|Homo sapiens keratinocyte growth factor
receptor 2 isoform KGFR protein.
Length = 820
Score = 179 bits (435), Expect = 2e-44
Identities = 103/253 (40%), Positives = 146/253 (57%), Gaps = 24/253 (9%)
Query: 235 FPLAPPDHWEIDRTDIVMKHKLGGGQYGDVYEAAW-------KRGNITVAVKTLKDDTMA 287
+ L WE R + + LG G +G V A + +TVAVK LKDD
Sbjct: 465 YELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATE 524
Query: 288 --LKDFLEEASIMKEM-RHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRA----GAR 340
L D + E +MK + +H N++ LLG CT++ P Y+I E+ S+GNL EYLRA G
Sbjct: 525 KDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGME 584
Query: 341 EC-----VPGAVV----LMYMATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADF 391
VP + L+ Q+A GM YL S+ IHRDLAARN LV EN+++K+ADF
Sbjct: 585 YSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADF 644
Query: 392 GLARLMRD-DTYTAHAGAKFPIKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYP 450
GLAR + + D Y + P+KW APE L ++ +SDVW+FG+L+WEI T G SPYP
Sbjct: 645 GLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYP 704
Query: 451 GVDLADVYHMLEK 463
G+ + +++ +L++
Sbjct: 705 GIPVEELFKLLKE 717
>AF097353-2|AAD31561.1| 554|Homo sapiens fibroblast growth factor
receptor 2 isoform IgIIIc isoform protein.
Length = 554
Score = 179 bits (435), Expect = 2e-44
Identities = 103/253 (40%), Positives = 146/253 (57%), Gaps = 24/253 (9%)
Query: 235 FPLAPPDHWEIDRTDIVMKHKLGGGQYGDVYEAAW-------KRGNITVAVKTLKDDTMA 287
+ L WE R + + LG G +G V A + +TVAVK LKDD
Sbjct: 253 YELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATE 312
Query: 288 --LKDFLEEASIMKEM-RHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRA----GAR 340
L D + E +MK + +H N++ LLG CT++ P Y+I E+ S+GNL EYLRA G
Sbjct: 313 KDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGME 372
Query: 341 EC-----VPGAVV----LMYMATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADF 391
VP + L+ Q+A GM YL S+ IHRDLAARN LV EN+++K+ADF
Sbjct: 373 YSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADF 432
Query: 392 GLARLMRD-DTYTAHAGAKFPIKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYP 450
GLAR + + D Y + P+KW APE L ++ +SDVW+FG+L+WEI T G SPYP
Sbjct: 433 GLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYP 492
Query: 451 GVDLADVYHMLEK 463
G+ + +++ +L++
Sbjct: 493 GIPVEELFKLLKE 505
>AF097353-1|AAD31560.1| 555|Homo sapiens fibroblast growth receptor
2 IgIIIb isoform protein.
Length = 555
Score = 179 bits (435), Expect = 2e-44
Identities = 103/253 (40%), Positives = 146/253 (57%), Gaps = 24/253 (9%)
Query: 235 FPLAPPDHWEIDRTDIVMKHKLGGGQYGDVYEAAW-------KRGNITVAVKTLKDDTMA 287
+ L WE R + + LG G +G V A + +TVAVK LKDD
Sbjct: 254 YELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATE 313
Query: 288 --LKDFLEEASIMKEM-RHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRA----GAR 340
L D + E +MK + +H N++ LLG CT++ P Y+I E+ S+GNL EYLRA G
Sbjct: 314 KDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGME 373
Query: 341 EC-----VPGAVV----LMYMATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADF 391
VP + L+ Q+A GM YL S+ IHRDLAARN LV EN+++K+ADF
Sbjct: 374 YSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADF 433
Query: 392 GLARLMRD-DTYTAHAGAKFPIKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYP 450
GLAR + + D Y + P+KW APE L ++ +SDVW+FG+L+WEI T G SPYP
Sbjct: 434 GLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYP 493
Query: 451 GVDLADVYHMLEK 463
G+ + +++ +L++
Sbjct: 494 GIPVEELFKLLKE 506
>AB208919-1|BAD92156.1| 814|Homo sapiens fibroblast growth factor
receptor 1 isoform 1 precursor variant protein.
Length = 814
Score = 179 bits (435), Expect = 2e-44
Identities = 104/253 (41%), Positives = 146/253 (57%), Gaps = 24/253 (9%)
Query: 235 FPLAPPDHWEIDRTDIVMKHKLGGGQYGDVYEAAW------KRGNIT-VAVKTLKDDTMA 287
+ L WE+ R +V+ LG G +G V A K +T VAVK LK D
Sbjct: 455 YELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATE 514
Query: 288 --LKDFLEEASIMKEM-RHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRA----GAR 340
L D + E +MK + +H N++ LLG CT++ P Y+I E+ S+GNL EYL+A G
Sbjct: 515 KDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLE 574
Query: 341 ECVP---------GAVVLMYMATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADF 391
C + L+ A Q+A GM YL S+ IHRDLAARN LV E++++K+ADF
Sbjct: 575 YCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADF 634
Query: 392 GLAR-LMRDDTYTAHAGAKFPIKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYP 450
GLAR + D Y + P+KW APE L ++ +SDVW+FG+LLWEI T G SPYP
Sbjct: 635 GLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYP 694
Query: 451 GVDLADVYHMLEK 463
GV + +++ +L++
Sbjct: 695 GVPVEELFKLLKE 707
>AB084153-1|BAC45037.1| 709|Homo sapiens isoform of FGFR2 protein.
Length = 709
Score = 179 bits (435), Expect = 2e-44
Identities = 103/253 (40%), Positives = 146/253 (57%), Gaps = 24/253 (9%)
Query: 235 FPLAPPDHWEIDRTDIVMKHKLGGGQYGDVYEAAW-------KRGNITVAVKTLKDDTMA 287
+ L WE R + + LG G +G V A + +TVAVK LKDD
Sbjct: 354 YELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATE 413
Query: 288 --LKDFLEEASIMKEM-RHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRA----GAR 340
L D + E +MK + +H N++ LLG CT++ P Y+I E+ S+GNL EYLRA G
Sbjct: 414 KDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGME 473
Query: 341 EC-----VPGAVV----LMYMATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADF 391
VP + L+ Q+A GM YL S+ IHRDLAARN LV EN+++K+ADF
Sbjct: 474 YSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADF 533
Query: 392 GLARLMRD-DTYTAHAGAKFPIKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYP 450
GLAR + + D Y + P+KW APE L ++ +SDVW+FG+L+WEI T G SPYP
Sbjct: 534 GLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYP 593
Query: 451 GVDLADVYHMLEK 463
G+ + +++ +L++
Sbjct: 594 GIPVEELFKLLKE 606
>X95425-1|CAA64700.1| 1037|Homo sapiens EHK-1 receptor tyrosine
kinase protein.
Length = 1037
Score = 178 bits (434), Expect = 3e-44
Identities = 90/227 (39%), Positives = 139/227 (61%), Gaps = 9/227 (3%)
Query: 244 EIDRTDIVMKHKLGGGQYGDVYEAAWK---RGNITVAVKTLKDD--TMALKDFLEEASIM 298
EI+ + I ++ +G G++G+V K + + VA+KTLK +DFL EASIM
Sbjct: 669 EIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRRDFLGEASIM 728
Query: 299 KEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIAS 358
+ HPN++ L GV T+ P I+TE+M G+L +L+ + + L+ M I++
Sbjct: 729 GQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFT--VIQLVGMLRGISA 786
Query: 359 GMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHA--GAKFPIKWTA 416
GM YL ++HRDLAARN L+ N + KV+DFGL+R++ DD A+ G K PI+WTA
Sbjct: 787 GMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTA 846
Query: 417 PEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
PE +A+ F++ SDVW++GI++WE+ +YG PY + DV +E+
Sbjct: 847 PEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEE 893
>U05012-1|AAA75374.1| 825|Homo sapiens TrkC protein.
Length = 825
Score = 178 bits (434), Expect = 3e-44
Identities = 95/225 (42%), Positives = 135/225 (60%), Gaps = 20/225 (8%)
Query: 245 IDRTDIVMKHKLGGGQYGDV-----YEAAWKRGNITVAVKTLKDDTMAL-KDFLEEASIM 298
I R DIV+K +LG G +G V Y + + + VAVK LKD T+A KDF EA ++
Sbjct: 533 IKRRDIVLKRELGEGAFGKVFLAECYNLSPTKDKMLVAVKALKDPTLAARKDFQREAELL 592
Query: 299 KEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECV------P-------G 345
++H ++V+ GVC P ++ E+M G+L ++LRA + P G
Sbjct: 593 TNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHGPNAMILVDGQPRQAKGELG 652
Query: 346 AVVLMYMATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLAR-LMRDDTYTA 404
++++A+QIASGM YL S+ F+HRDLA RNCLVG N LVK+ DFG++R + D Y
Sbjct: 653 LSQMLHIASQIASGMVYLASQHFVHRDLATRNCLVGANLLVKIGDFGMSRDVYSTDYYRV 712
Query: 405 HAGAKFPIKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPY 449
PI+W PE + Y F+T+SDVW+FG++LWEI TYG P+
Sbjct: 713 GGHTMLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFTYGKQPW 757
>M37722-1|AAA75007.1| 731|Homo sapiens basic fibroblast growth
factor receptor protein protein.
Length = 731
Score = 178 bits (434), Expect = 3e-44
Identities = 105/250 (42%), Positives = 146/250 (58%), Gaps = 25/250 (10%)
Query: 239 PPD-HWEIDRTDIVMKHKLGGGQYGDVYEAAW------KRGNIT-VAVKTLKDDTMA--L 288
P D WE+ R +V+ LG G +G V A K +T VAVK LK D L
Sbjct: 375 PEDLRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDL 434
Query: 289 KDFLEEASIMKEM-RHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRA----GARECV 343
D + E +MK + +H N++ LLG CT++ P Y+I E+ S+GNL EYL+A G C
Sbjct: 435 SDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCY 494
Query: 344 P---------GAVVLMYMATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLA 394
+ L+ A Q+A GM YL S+ IHRDLAARN LV E++++K+ADFGLA
Sbjct: 495 NPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLA 554
Query: 395 R-LMRDDTYTAHAGAKFPIKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVD 453
R + D Y + P+KW APE L ++ +SDVW+FG+LLWEI T G SPYPGV
Sbjct: 555 RDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVP 614
Query: 454 LADVYHMLEK 463
+ +++ +L++
Sbjct: 615 VEELFKLLKE 624
>L36644-1|AAA74245.1| 991|Homo sapiens receptor protein-tyrosine
kinase protein.
Length = 991
Score = 178 bits (434), Expect = 3e-44
Identities = 90/227 (39%), Positives = 139/227 (61%), Gaps = 9/227 (3%)
Query: 244 EIDRTDIVMKHKLGGGQYGDVYEAAWK---RGNITVAVKTLKDD--TMALKDFLEEASIM 298
EI+ + I ++ +G G++G+V K + + VA+KTLK +DFL EASIM
Sbjct: 623 EIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRRDFLGEASIM 682
Query: 299 KEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIAS 358
+ HPN++ L GV T+ P I+TE+M G+L +L+ + + L+ M I++
Sbjct: 683 GQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFT--VIQLVGMLRGISA 740
Query: 359 GMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHA--GAKFPIKWTA 416
GM YL ++HRDLAARN L+ N + KV+DFGL+R++ DD A+ G K PI+WTA
Sbjct: 741 GMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTA 800
Query: 417 PEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
PE +A+ F++ SDVW++GI++WE+ +YG PY + DV +E+
Sbjct: 801 PEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEE 847
>AB209375-1|BAD92612.1| 1017|Homo sapiens ephrin receptor EphA5
isoform a variant protein.
Length = 1017
Score = 178 bits (434), Expect = 3e-44
Identities = 90/227 (39%), Positives = 139/227 (61%), Gaps = 9/227 (3%)
Query: 244 EIDRTDIVMKHKLGGGQYGDVYEAAWK---RGNITVAVKTLKDD--TMALKDFLEEASIM 298
EI+ + I ++ +G G++G+V K + + VA+KTLK +DFL EASIM
Sbjct: 683 EIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRRDFLGEASIM 742
Query: 299 KEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIAS 358
+ HPN++ L GV T+ P I+TE+M G+L +L+ + + L+ M I++
Sbjct: 743 GQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFT--VIQLVGMLRGISA 800
Query: 359 GMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHA--GAKFPIKWTA 416
GM YL ++HRDLAARN L+ N + KV+DFGL+R++ DD A+ G K PI+WTA
Sbjct: 801 GMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKIPIRWTA 860
Query: 417 PEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEK 463
PE +A+ F++ SDVW++GI++WE+ +YG PY + DV +E+
Sbjct: 861 PEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEE 907
>X04434-1|CAA28030.1| 1367|Homo sapiens IGF-I receptor protein.
Length = 1367
Score = 177 bits (431), Expect = 7e-44
Identities = 94/228 (41%), Positives = 131/228 (57%), Gaps = 15/228 (6%)
Query: 240 PDHWEIDRTDIVMKHKLGGGQYGDVYEAAWK-----RGNITVAVKTLKDDTMALK--DFL 292
PD WE+ R I M +LG G +G VYE K VA+KT+ + + +FL
Sbjct: 989 PDEWEVAREKITMSRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVNEAASMRERIEFL 1048
Query: 293 EEASIMKEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARE-------CVPG 345
EAS+MKE ++V+LLGV ++ P +I E M+RG+L YLR+ E P
Sbjct: 1049 NEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSLRPEMENNPVLAPPS 1108
Query: 346 AVVLMYMATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLAR-LMRDDTYTA 404
++ MA +IA GM+YL + F+HRDLAARNC+V E+ VK+ DFG+ R + D Y
Sbjct: 1109 LSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDFGMTRDIYETDYYRK 1168
Query: 405 HAGAKFPIKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGV 452
P++W +PE L F+T SDVW+FG++LWEIAT PY G+
Sbjct: 1169 GGKGLLPVRWMSPESLKDGVFTTYSDVWSFGVVLWEIATLAEQPYQGL 1216
>U12140-1|AAC51371.1| 822|Homo sapiens tyrosine kinase receptor
p145TRK-B protein.
Length = 822
Score = 177 bits (431), Expect = 7e-44
Identities = 94/222 (42%), Positives = 135/222 (60%), Gaps = 17/222 (7%)
Query: 245 IDRTDIVMKHKLGGGQYGDV-----YEAAWKRGNITVAVKTLKDDT-MALKDFLEEASIM 298
I R +IV+K +LG G +G V Y ++ I VAVKTLKD + A KDF EA ++
Sbjct: 533 IKRHNIVLKRELGEGAFGKVFLAECYNLCPEQDKILVAVKTLKDASDNARKDFHREAELL 592
Query: 299 KEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECV-------PGAVV--- 348
++H ++V+ GVC P ++ E+M G+L ++LRA + V P +
Sbjct: 593 TNLQHEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKFLRAHGPDAVLMAEGNPPTELTQSQ 652
Query: 349 LMYMATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLAR-LMRDDTYTAHAG 407
++++A QIA+GM YL S+ F+HRDLA RNCLVGEN LVK+ DFG++R + D Y
Sbjct: 653 MLHIAQQIAAGMVYLASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDVYSTDYYRVGGH 712
Query: 408 AKFPIKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPY 449
PI+W PE + Y F+T+SDVW+ G++LWEI TYG P+
Sbjct: 713 TMLPIRWMPPESIMYRKFTTESDVWSLGVVLWEIFTYGKQPW 754
>S76473-1|AAB33109.1| 822|Homo sapiens trkB protein.
Length = 822
Score = 177 bits (431), Expect = 7e-44
Identities = 94/222 (42%), Positives = 135/222 (60%), Gaps = 17/222 (7%)
Query: 245 IDRTDIVMKHKLGGGQYGDV-----YEAAWKRGNITVAVKTLKDDT-MALKDFLEEASIM 298
I R +IV+K +LG G +G V Y ++ I VAVKTLKD + A KDF EA ++
Sbjct: 533 IKRHNIVLKRELGEGAFGKVFLAECYNLCPEQDKILVAVKTLKDASDNARKDFHREAELL 592
Query: 299 KEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECV-------PGAVV--- 348
++H ++V+ GVC P ++ E+M G+L ++LRA + V P +
Sbjct: 593 TNLQHEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKFLRAHGPDAVLMAEGNPPTELTQSQ 652
Query: 349 LMYMATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLAR-LMRDDTYTAHAG 407
++++A QIA+GM YL S+ F+HRDLA RNCLVGEN LVK+ DFG++R + D Y
Sbjct: 653 MLHIAQQIAAGMVYLASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDVYSTDYYRVGGH 712
Query: 408 AKFPIKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPY 449
PI+W PE + Y F+T+SDVW+ G++LWEI TYG P+
Sbjct: 713 TMLPIRWMPPESIMYRKFTTESDVWSLGVVLWEIFTYGKQPW 754
>L07868-1|AAB59446.1| 1308|Homo sapiens receptor tyrosine kinase
protein.
Length = 1308
Score = 177 bits (431), Expect = 7e-44
Identities = 96/231 (41%), Positives = 135/231 (58%), Gaps = 10/231 (4%)
Query: 245 IDRTDIVMKHKLGGGQYGDVYEAAW----KRGNITVAVKTLKDDT--MALKDFLEEASIM 298
+ T++ LG G +G VY+ W + I VA+K L + T A +F++EA IM
Sbjct: 713 LKETELKRVKVLGSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKANVEFMDEALIM 772
Query: 299 KEMRHPNLVQLLGVCTREPPFYIITEFMSRGNLLEYLRAGARECVPGAVVLMYMATQIAS 358
M HP+LV+LLGVC P ++T+ M G LLEY+ G+ +L+ QIA
Sbjct: 773 ASMDHPHLVRLLGVCL-SPTIQLVTQLMPHGCLLEYVHEHKDNI--GSQLLLNWCVQIAK 829
Query: 359 GMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLARLMRDDTYTAHA-GAKFPIKWTAP 417
GM YLE R +HRDLAARN LV + VK+ DFGLARL+ D +A G K PIKW A
Sbjct: 830 GMMYLEERRLVHRDLAARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGGKMPIKWMAL 889
Query: 418 EGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHMLEKVKFAP 468
E + Y F+ +SDVW++G+ +WE+ T+G PY G+ ++ +LEK + P
Sbjct: 890 ECIHYRKFTHQSDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLEKGERLP 940
>BC114918-1|AAI14919.1| 823|Homo sapiens MERTK protein protein.
Length = 823
Score = 177 bits (431), Expect = 7e-44
Identities = 100/232 (43%), Positives = 140/232 (60%), Gaps = 15/232 (6%)
Query: 245 IDRTDIVMKHKLGGGQYGDVYEAAWKRGNIT---VAVKTLKDDTMA---LKDFLEEASIM 298
IDR +++ LG G++G V E K+ + T VAVKT+K D + +++FL EA+ M
Sbjct: 406 IDRNLLILGKILGEGEFGSVMEGNLKQEDGTSLKVAVKTMKLDNSSQREIEEFLSEAACM 465
Query: 299 KEMRHPNLVQLLGVCTRE-----PPFYIITEFMSRGNLLEYLRAGARECVPGAV---VLM 350
K+ HPN+++LLGVC P +I FM G+L YL E P + L+
Sbjct: 466 KDFSHPNVIRLLGVCIEMSSQGIPKPMVILPFMKYGDLHTYLLYSRLETGPKHIPLQTLL 525
Query: 351 YMATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLAR-LMRDDTYTAHAGAK 409
IA GM YL +R+F+HRDLAARNC++ ++ V VADFGL++ + D Y AK
Sbjct: 526 KFMVDIALGMEYLSNRNFLHRDLAARNCMLRDDMTVCVADFGLSKKIYSGDYYRQGRIAK 585
Query: 410 FPIKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHML 461
P+KW A E LA +++KSDVWAFG+ +WEIAT GM+PYPGV ++Y L
Sbjct: 586 MPVKWIAIESLADRVYTSKSDVWAFGVTMWEIATRGMTPYPGVQNHEMYDYL 637
>BC114917-1|AAI14918.1| 823|Homo sapiens MERTK protein protein.
Length = 823
Score = 177 bits (431), Expect = 7e-44
Identities = 100/232 (43%), Positives = 140/232 (60%), Gaps = 15/232 (6%)
Query: 245 IDRTDIVMKHKLGGGQYGDVYEAAWKRGNIT---VAVKTLKDDTMA---LKDFLEEASIM 298
IDR +++ LG G++G V E K+ + T VAVKT+K D + +++FL EA+ M
Sbjct: 406 IDRNLLILGKILGEGEFGSVMEGNLKQEDGTSLKVAVKTMKLDNSSQREIEEFLSEAACM 465
Query: 299 KEMRHPNLVQLLGVCTRE-----PPFYIITEFMSRGNLLEYLRAGARECVPGAV---VLM 350
K+ HPN+++LLGVC P +I FM G+L YL E P + L+
Sbjct: 466 KDFSHPNVIRLLGVCIEMSSQGIPKPMVILPFMKYGDLHTYLLYSRLETGPKHIPLQTLL 525
Query: 351 YMATQIASGMSYLESRSFIHRDLAARNCLVGENHLVKVADFGLAR-LMRDDTYTAHAGAK 409
IA GM YL +R+F+HRDLAARNC++ ++ V VADFGL++ + D Y AK
Sbjct: 526 KFMVDIALGMEYLSNRNFLHRDLAARNCMLRDDMTVCVADFGLSKKIYSGDYYRQGRIAK 585
Query: 410 FPIKWTAPEGLAYNTFSTKSDVWAFGILLWEIATYGMSPYPGVDLADVYHML 461
P+KW A E LA +++KSDVWAFG+ +WEIAT GM+PYPGV ++Y L
Sbjct: 586 MPVKWIAIESLADRVYTSKSDVWAFGVTMWEIATRGMTPYPGVQNHEMYDYL 637
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.320 0.135 0.416
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 69,940,147
Number of Sequences: 224733
Number of extensions: 2885137
Number of successful extensions: 14171
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 2428
Number of HSP's successfully gapped in prelim test: 942
Number of HSP's that attempted gapping in prelim test: 5643
Number of HSP's gapped (non-prelim): 4256
length of query: 473
length of database: 73,234,838
effective HSP length: 93
effective length of query: 380
effective length of database: 52,334,669
effective search space: 19887174220
effective search space used: 19887174220
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 67 (31.1 bits)
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