Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA002064-TA|BGIBMGA002064-PA|IPR001054|Adenylyl cyclase
class-3/4/guanylyl cyclase
(566 letters)
Database: nematostella
59,808 sequences; 16,821,457 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
SB_38875| Best HMM Match : No HMM Matches (HMM E-Value=.) 285 7e-77
SB_51990| Best HMM Match : Guanylate_cyc (HMM E-Value=0) 215 1e-55
SB_10830| Best HMM Match : No HMM Matches (HMM E-Value=.) 160 2e-39
SB_37135| Best HMM Match : Guanylate_cyc (HMM E-Value=0) 110 3e-24
SB_37259| Best HMM Match : No HMM Matches (HMM E-Value=.) 104 2e-22
SB_50980| Best HMM Match : Guanylate_cyc (HMM E-Value=0) 92 1e-18
SB_43991| Best HMM Match : No HMM Matches (HMM E-Value=.) 89 9e-18
SB_11488| Best HMM Match : No HMM Matches (HMM E-Value=.) 85 1e-16
SB_10421| Best HMM Match : Guanylate_cyc (HMM E-Value=0) 83 8e-16
SB_58458| Best HMM Match : Guanylate_cyc (HMM E-Value=1.2e-36) 77 4e-14
SB_58457| Best HMM Match : Guanylate_cyc (HMM E-Value=0) 75 1e-13
SB_28889| Best HMM Match : ANF_receptor (HMM E-Value=1.1e-34) 73 6e-13
SB_24605| Best HMM Match : HNOB (HMM E-Value=0) 72 1e-12
SB_35409| Best HMM Match : Guanylate_cyc (HMM E-Value=1.7e-17) 69 1e-11
SB_58488| Best HMM Match : Guanylate_cyc (HMM E-Value=2.5e-31) 68 2e-11
SB_29094| Best HMM Match : Guanylate_cyc (HMM E-Value=7.9e-07) 49 9e-06
SB_1188| Best HMM Match : Guanylate_cyc (HMM E-Value=6.7) 49 1e-05
SB_11487| Best HMM Match : Guanylate_cyc (HMM E-Value=2.3e-06) 46 6e-05
SB_13681| Best HMM Match : Guanylate_cyc (HMM E-Value=2.8e-27) 44 3e-04
SB_29093| Best HMM Match : HNOBA (HMM E-Value=0) 43 6e-04
SB_18463| Best HMM Match : Guanylate_cyc (HMM E-Value=1.5) 41 0.003
SB_50731| Best HMM Match : Guanylate_cyc (HMM E-Value=0.76) 39 0.009
SB_51348| Best HMM Match : No HMM Matches (HMM E-Value=.) 35 0.15
SB_48593| Best HMM Match : 7tm_1 (HMM E-Value=4.2039e-45) 34 0.27
SB_21756| Best HMM Match : No HMM Matches (HMM E-Value=.) 31 2.5
SB_23414| Best HMM Match : Tetraspannin (HMM E-Value=3.8e-08) 31 3.3
SB_10801| Best HMM Match : No HMM Matches (HMM E-Value=.) 31 3.3
SB_54104| Best HMM Match : PolyA_pol (HMM E-Value=1.29998e-41) 29 7.6
SB_42324| Best HMM Match : No HMM Matches (HMM E-Value=.) 29 7.6
SB_27050| Best HMM Match : Pkinase_Tyr (HMM E-Value=1e-06) 29 7.6
SB_11543| Best HMM Match : Synaptobrevin (HMM E-Value=0.00034) 29 7.6
SB_59669| Best HMM Match : No HMM Matches (HMM E-Value=.) 29 10.0
>SB_38875| Best HMM Match : No HMM Matches (HMM E-Value=.)
Length = 1116
Score = 285 bits (699), Expect = 7e-77
Identities = 162/385 (42%), Positives = 225/385 (58%), Gaps = 12/385 (3%)
Query: 123 RVAHIINVIVLGLSALVFACLLACLSRPAMNEIYLLTISYVVLVAFLLIEFSFAGTSVLR 182
+V+ +I V G L+ L A PA L + ++ + + LL++ G L
Sbjct: 318 QVSRLIVTGVYGAFYLLLVVLYASKLYPARLMKCLPYLVWLGIFSQLLVD-QVLGYDPLT 376
Query: 183 SLTVSTGACSLFTYVTYATLPVRLHEATIGGLALAAVNI---GAHLLLD-NSSDMQLYCT 238
+ S G + F++++Y LP RL + + ++ ++ G ++ N QL
Sbjct: 377 P-SDSVGMFAFFSFISYVMLPARLALCAVFAIMISIAHLVVAGTQARMNLNYLGQQLVAN 435
Query: 239 IATLIACNAAGMLTHQPRELAQRRAFLETRDCVEAXXXXXXXXXXXXXXXXSVLPRHVAM 298
+ N G + + + QRR+ LETR+ +E SVLP+HVA
Sbjct: 436 TLVFVCANILGAIDYHIADRKQRRSVLETRESLEVKLTLDAQNQQQRRLLLSVLPKHVAE 495
Query: 299 EMKADIASQPR----HEQFHKIYIQRYENVSILFADICGFTSLSDQCTAEELVRLLNELF 354
EM D F K++I+ ++ SILFADI GFT LS +CTAE+L+ LNELF
Sbjct: 496 EMTKDFEGDGNPALTDNAFKKLFIRTHDTCSILFADIVGFTELSSKCTAEQLIVTLNELF 555
Query: 355 ARFDRLAAEHHCLRIKLLGDCYYCVSGLPEARDDHAKCCVEMGLDMIDAIALVREVMAV- 413
A FD+LAA++HCLRIK+LGDCYYC+SGL ++ + HA C V MGLDM++ IA VRE V
Sbjct: 556 ANFDKLAAKNHCLRIKILGDCYYCISGLDDSCN-HALCAVNMGLDMVEHIAHVREEKGVK 614
Query: 414 NVNMRVGIHTGRVHCVVLGLRKWQFDVWSNDVTLANYMESGGVAGRVHITKETLCCLGDD 473
++NMRVGIHTG V VLG RKWQF+ WSNDVTLAN+MESGG+ GRVHI++ TL + D
Sbjct: 615 SLNMRVGIHTGMVLAGVLGQRKWQFEAWSNDVTLANHMESGGIPGRVHISEPTLNSIKDY 674
Query: 474 YKVEPGHGGYRNAYLKDHNIETYLI 498
++VE G GG R+ YL D I+TYLI
Sbjct: 675 FEVEDGDGGSRDDYLADKKIKTYLI 699
Score = 44.0 bits (99), Expect = 3e-04
Identities = 31/93 (33%), Positives = 46/93 (49%), Gaps = 1/93 (1%)
Query: 414 NVNMRVGIHTGRVHCVVLGLRKWQFDVWSNDVTLANYMESGGVAGRVHITKETLCCLGDD 473
N ++ GI G + V+G +K +D+W N V +A+ ME+ G AG + IT +T + D
Sbjct: 1018 NDSVVFGICQGPIVAGVIGAKKPHYDIWGNTVNVASRMETTGKAGCIQITAQTYETIKDK 1077
Query: 474 YKVEPGHGGYRNAYLKDHNIETYLIVPDDTSRV 506
V G R K I YL +TS+V
Sbjct: 1078 DFVFVYRGAVR-VKGKGQLITYYLTGRKNTSQV 1109
>SB_51990| Best HMM Match : Guanylate_cyc (HMM E-Value=0)
Length = 1055
Score = 215 bits (524), Expect = 1e-55
Identities = 105/187 (56%), Positives = 131/187 (70%), Gaps = 2/187 (1%)
Query: 313 FHKIYIQRYENVSILFADICGFTSLSDQCTAEELVRLLNELFARFDRLAAEHHCLRIKLL 372
F + R ENVSILFADI GFT +S +A++LVRLLN+LF RFDRL +HC +I L
Sbjct: 297 FRPFQMHRMENVSILFADIVGFTKMSSNKSADQLVRLLNDLFGRFDRLTEYNHCEKISTL 356
Query: 373 GDCYYCVSGLPEARDDHAKCCVEMGLDMIDAIALVREVMAVNVNMRVGIHTGRVHCVVLG 432
GDCYYCV+G P+ +HA CVEMGLDM++ I +V+MRVG+HTG V C ++G
Sbjct: 357 GDCYYCVAGCPKPTPNHATYCVEMGLDMLEQIKEFDNDTDNDVDMRVGVHTGTVLCGIVG 416
Query: 433 LRKWQFDVWSNDVTLANYMESGGVAGRVHITKETLCCLGDDYKVEPGHGGYRNAYLKDHN 492
++++FDVWSNDVTLAN ME+ G+ GRVHIT+ T+ L D Y VE GHG RNA LK
Sbjct: 417 TKRFKFDVWSNDVTLANRMETAGLPGRVHITEATVGFLRDQYIVENGHGETRNAALK--G 474
Query: 493 IETYLIV 499
I TY IV
Sbjct: 475 ITTYFIV 481
Score = 70.9 bits (166), Expect = 3e-12
Identities = 46/176 (26%), Positives = 83/176 (47%), Gaps = 15/176 (8%)
Query: 317 YIQRYENVSILFADICGFTSLSDQCT--AEELVRLLNELFARFDRLAAEHHCLRIKLL-- 372
Y Y N ++FA I F+ ++ +E +R+LNEL FD L + ++ +
Sbjct: 857 YSMNYNNAGVMFASIVNFSDFYEENFEGGKECIRVLNELVGDFDELLDNIEYMEVEKIKT 916
Query: 373 --GDCYYCVSGLPEARD--------DHAKCCVEMGLDMIDAIALVRE-VMAVNVNMRVGI 421
G + +GL + + +H K VE L+M + + E ++ +R+G
Sbjct: 917 VNGSTFMAGAGLNQEDNIRREIHPYEHLKQLVEFALEMFNVVDRFNEHMLGFKFKLRIGF 976
Query: 422 HTGRVHCVVLGLRKWQFDVWSNDVTLANYMESGGVAGRVHITKETLCCLGDDYKVE 477
+ G V V+G K +D+W + V LA+ M+S GV ++ +++ T L D + E
Sbjct: 977 NAGPVTAGVIGTTKLLYDIWGDTVNLASRMDSTGVPEKIQVSESTKEMLNDFFIFE 1032
>SB_10830| Best HMM Match : No HMM Matches (HMM E-Value=.)
Length = 1006
Score = 160 bits (389), Expect = 2e-39
Identities = 85/172 (49%), Positives = 110/172 (63%), Gaps = 4/172 (2%)
Query: 194 FTYVTYATLPVRLHEATIGGLALAAVNIGAHLLLDNSSDMQLYCTIATL---IACNAAGM 250
F Y+TY LPVR+ A GG L A+++ + ++ ++ + L I N G+
Sbjct: 283 FIYMTYTMLPVRMRIAVFGGCLLLALHLISSACVNRNNPNLARLLVGNLLLFICANITGV 342
Query: 251 LTHQPRELAQRRAFLETRDCVEAXXXXXXXXXXXXXXXXSVLPRHVAMEMKADIASQ-PR 309
TH P E++QR+AFLETR C+EA SVLPR+VAMEMK DI S +
Sbjct: 343 FTHYPTEISQRQAFLETRRCIEARLTIQKENQNQERLLLSVLPRYVAMEMKDDIESGISQ 402
Query: 310 HEQFHKIYIQRYENVSILFADICGFTSLSDQCTAEELVRLLNELFARFDRLA 361
+ QFHKIYIQR+ENVSILFADI GFT LS QCTA+ L++ LNEL+ARFD+LA
Sbjct: 403 NSQFHKIYIQRHENVSILFADIEGFTVLSSQCTAQSLIKTLNELYARFDQLA 454
Score = 160 bits (389), Expect = 2e-39
Identities = 68/96 (70%), Positives = 82/96 (85%)
Query: 363 EHHCLRIKLLGDCYYCVSGLPEARDDHAKCCVEMGLDMIDAIALVREVMAVNVNMRVGIH 422
E+HCLRIK+LGDCYYCVSGLP+ R DHA C+EMGL MIDAI+ VR+ VN+NMRVG+H
Sbjct: 499 ENHCLRIKILGDCYYCVSGLPDPRPDHAHSCIEMGLAMIDAISFVRDATQVNLNMRVGVH 558
Query: 423 TGRVHCVVLGLRKWQFDVWSNDVTLANYMESGGVAG 458
G+VH VLGL KWQ+DVWS+DVT+AN+MESGG+ G
Sbjct: 559 MGKVHSGVLGLVKWQYDVWSDDVTIANHMESGGLPG 594
Score = 42.7 bits (96), Expect = 8e-04
Identities = 35/135 (25%), Positives = 58/135 (42%), Gaps = 13/135 (9%)
Query: 231 SDMQLYCTIATLIACNAAGMLTHQPRELAQRRAFLETRDCVEAXXXXXXXXXXXXXXXXS 290
SD+ + + ++A A G L Q R FL E +
Sbjct: 793 SDLSILIVVIFILALTAHGYLHEQ----ISRLDFLWKLQATEEKKEMEQLREYNKKLLYN 848
Query: 291 VLPRHVAMEMKADIASQPRHEQFHKIYIQRYENVSILFADICGFTSLSDQCTAE----EL 346
+LP HVA A+ ++E +Y Q + V+++F++IC F+ + A E
Sbjct: 849 ILPVHVAQHFLGHKAN--KNED---LYYQSCDKVAVMFSNICNFSDFYTELDANGEGVEC 903
Query: 347 VRLLNELFARFDRLA 361
+RLLNE+ A FD ++
Sbjct: 904 LRLLNEILADFDEVS 918
Score = 37.1 bits (82), Expect = 0.038
Identities = 19/64 (29%), Positives = 37/64 (57%), Gaps = 2/64 (3%)
Query: 401 IDAIALVREVMAVNVNMRVGIHTGRVHCVVLGLRKWQFDVWSNDVTLANYMESGGVAGRV 460
++ + L+ E++A + + V ++ G V V+G K Q+D+W + V +A+ M S G +
Sbjct: 901 VECLRLLNEILA-DFD-EVSLNFGPVVAGVIGAHKPQYDIWGDTVNVASRMYSTGKDNHI 958
Query: 461 HITK 464
+TK
Sbjct: 959 QVTK 962
>SB_37135| Best HMM Match : Guanylate_cyc (HMM E-Value=0)
Length = 584
Score = 110 bits (265), Expect = 3e-24
Identities = 50/150 (33%), Positives = 96/150 (64%), Gaps = 2/150 (1%)
Query: 319 QRYENVSILFADICGFTSLSDQCTAEELVRLLNELFARFDRLAAEHHCLRIKLLGDCYYC 378
+ + NV+ILF+D+ GFT++ ++V +LN ++ FD+L+ +H+ +++ +GD Y
Sbjct: 408 ETFSNVTILFSDVVGFTTICSLIAPMQVVTMLNCMYTTFDKLSEKHNVYKVETIGDAYMV 467
Query: 379 VSGLPEARDDHAKCCVEMGLDMIDAIALVREVMAVN--VNMRVGIHTGRVHCVVLGLRKW 436
VSG+PE HA+ +M L+M+ A+ + + +N + +R+GIHTG V V+GL+
Sbjct: 468 VSGIPERTKYHAEHVADMALNMLSAMPEIEDPAGLNDHLRIRIGIHTGTVVAGVVGLKMP 527
Query: 437 QFDVWSNDVTLANYMESGGVAGRVHITKET 466
++ ++ + V A+ MES G+A +H++++T
Sbjct: 528 RYCLFGDTVNTASRMESTGLAMAIHVSEDT 557
>SB_37259| Best HMM Match : No HMM Matches (HMM E-Value=.)
Length = 1690
Score = 104 bits (249), Expect = 2e-22
Identities = 68/208 (32%), Positives = 110/208 (52%), Gaps = 5/208 (2%)
Query: 303 DIASQPRHEQFHKIYIQRYENVSILFADICGFTSLSDQCTAEELVRLLNELFARFDRLAA 362
D+A++ ++Q I + +NV++LF+DI GFT++ +C+A ++V +L L+ +FD+L
Sbjct: 441 DVANKLINKQ--PIPARHIQNVTMLFSDIVGFTAICGKCSAMDVVEMLKSLYTKFDKLCG 498
Query: 363 EHHCLRIKLLGDCYYCVSGLPE--ARDDHAKCCVEMGLDMIDAIALVREVMAVNVNMRVG 420
E +++ +GD Y G+ + A M + MID I V V + MRVG
Sbjct: 499 ELDLYKVETIGDAYVVAGGVQNHCGTAEDAYHVALMAVGMIDHIRDVLSPEGVPLKMRVG 558
Query: 421 IHTGRVHCVVLGLRKWQFDVWSNDVTLANYMESGGVAGRVHITKETLCCLGDDYKVEPGH 480
IHTG V V+G + ++ ++ +DVTLAN MES AGR++I+ T + +
Sbjct: 559 IHTGSVLSGVVGTKMPRYCLFGHDVTLANKMESESEAGRINISPTTYEEKANLDLGDSRE 618
Query: 481 GGYRNAYLKDHNIETYLIVPDDTSRVDK 508
R Y D N LIV +D + K
Sbjct: 619 FNERRIY-DDQNTSDLLIVAEDVIGLSK 645
Score = 89.4 bits (212), Expect = 7e-18
Identities = 47/147 (31%), Positives = 88/147 (59%), Gaps = 3/147 (2%)
Query: 320 RYENVSILFADICGFTSLSDQCTAE-ELVRLLNELFARFDRLAAEHHCL-RIKLLGDCYY 377
+YE V+I+F+ I FT+ ++ E+V +LNE++ FD+L + + +++ +GD Y
Sbjct: 913 KYEIVTIMFSGIVDFTNYCNKIKEPMEIVEMLNEVYTEFDQLTDSNDDIYKVETVGDKYM 972
Query: 378 CVSGLPEARDDHAKCCVEMGLDMIDAIALVREVMAVNVNMRVGIHTGRVHCVVLGLRKWQ 437
VSGLP D HA + LDMID I+ + + + + +GIH+G V V+G +K +
Sbjct: 973 AVSGLPTRCDKHALNIANLALDMID-ISKGMKAKGIQLQVTIGIHSGEVVAGVVGQKKPR 1031
Query: 438 FDVWSNDVTLANYMESGGVAGRVHITK 464
+ ++ N V L + E+ G+ G++++++
Sbjct: 1032 YCLFGNTVNLTSRTETTGLKGKINVSE 1058
Score = 87.8 bits (208), Expect = 2e-17
Identities = 52/169 (30%), Positives = 90/169 (53%), Gaps = 5/169 (2%)
Query: 304 IASQPRHEQFHKIYIQRYENVSILFADICGFTSLSDQCTAEELVRLLNELFARFDRLA-- 361
+A++ RH + + +R E V++LF+ I F + E+V LLN ++ +FD L
Sbjct: 1447 VANELRHNR--PVQAERAEMVTLLFSGIVDFAQICKNSKPMEIVMLLNNIYTKFDMLTDP 1504
Query: 362 AEHHCLRIKLLGDCYYCVSGLPEARDDHAKCCVEMGLDMIDAIALVREVMAVNVNMRVGI 421
+ + +++ +GD Y VSGLPE HA+ M LDM + + +++GI
Sbjct: 1505 SINDVYKVETVGDKYMAVSGLPERCAFHARSICNMALDMKHVTQSIIH-KGDKIQIKIGI 1563
Query: 422 HTGRVHCVVLGLRKWQFDVWSNDVTLANYMESGGVAGRVHITKETLCCL 470
H+G V V+G + ++ ++ N V L + E+ G G+V+IT+ T CL
Sbjct: 1564 HSGEVVAGVVGHKTPRYCLFGNTVNLTSRTETTGAPGQVNITEFTYRCL 1612
>SB_50980| Best HMM Match : Guanylate_cyc (HMM E-Value=0)
Length = 313
Score = 91.9 bits (218), Expect = 1e-18
Identities = 52/141 (36%), Positives = 80/141 (56%), Gaps = 4/141 (2%)
Query: 319 QRYENVSILFADICGFTSLSDQCTAEELVRLLNELFARFDRLAAEHHCLRIKLLGDCYYC 378
+ ++ VSI F+DI GFTSLS + T ++V LLN+L+ FD + E+ +++ +GD Y
Sbjct: 170 ESFDEVSIYFSDIVGFTSLSAESTPMQVVTLLNDLYTLFDDIIREYDVYKVETIGDAYMV 229
Query: 379 VSGLPEARDD-HAKCCVEMGLDMIDAIA---LVREVMAVNVNMRVGIHTGRVHCVVLGLR 434
VSGLP HA M L ++DA+ VR + +RVGIH+G V V+G
Sbjct: 230 VSGLPIRNGSRHAGEIARMSLHLVDAVQTEFCVRHKPEYKLKLRVGIHSGPVVAGVVGNT 289
Query: 435 KWQFDVWSNDVTLANYMESGG 455
++ ++ + V A+ MES G
Sbjct: 290 MPRYCLFGDTVNTASRMESNG 310
>SB_43991| Best HMM Match : No HMM Matches (HMM E-Value=.)
Length = 1149
Score = 89.0 bits (211), Expect = 9e-18
Identities = 54/159 (33%), Positives = 86/159 (54%), Gaps = 7/159 (4%)
Query: 304 IASQPRHEQFHK---IYIQRYENVSILFADICGFTSLSDQCTAEELVRLLNELFARFDRL 360
I +P EQ K + + + V+I F+DI GFTSLS + T ++V LN+L+ FD +
Sbjct: 856 IIIKPVAEQLKKGKAVEAESFNEVTIYFSDIVGFTSLSAESTPMQVVTFLNDLYTIFDDI 915
Query: 361 AAEHHCLRIKLLGDCYYCVSGLPEARD-DHAKCCVEMGLDMIDAIA---LVREVMAVNVN 416
E+ +++ +GD Y SGLP HA +M L ++DA++ +VR +
Sbjct: 916 IQEYDVYKVETIGDAYMVASGLPIRNGRRHAGEIAKMALHLVDAVSHNFIVRHKPEYKLQ 975
Query: 417 MRVGIHTGRVHCVVLGLRKWQFDVWSNDVTLANYMESGG 455
+RVG HTG V V+G ++ ++ + V A+ MES G
Sbjct: 976 LRVGCHTGPVVAGVVGNTMARYCLFGDTVNTASRMESNG 1014
>SB_11488| Best HMM Match : No HMM Matches (HMM E-Value=.)
Length = 250
Score = 85.0 bits (201), Expect = 1e-16
Identities = 44/179 (24%), Positives = 94/179 (52%), Gaps = 13/179 (7%)
Query: 291 VLPRHVAMEMKADIASQPRHEQFHKIYIQRYENVSILFADICGFTSLSDQCTAEELVRLL 350
+LPR +A ++KA + + + + V++ + DI FT ++ ++++LL
Sbjct: 45 MLPRLIADQLKAGLP----------LKAESFSEVTVFYCDIVDFTVITALSEPMQVIKLL 94
Query: 351 NELFARFDRLAAEHHCLRIKLLGDCYYCVSGLPEARDD-HAKCCVEMGLDMIDAIA--LV 407
N++++ FD + + +++ +GD VSGLPE + HA M L +++ + +
Sbjct: 95 NDVYSLFDTIMGRYDIYKVETVGDSCLVVSGLPERNGNRHASEIAAMSLHLLNYVTDFRI 154
Query: 408 REVMAVNVNMRVGIHTGRVHCVVLGLRKWQFDVWSNDVTLANYMESGGVAGRVHITKET 466
+ + R+GIHTG ++GL+K ++D++ V + ++ES G+ +H++ T
Sbjct: 155 EHLPDTRLEFRMGIHTGPCVAGIVGLKKPRYDIFGETVNIVKHLESAGIPQSIHVSSPT 213
>SB_10421| Best HMM Match : Guanylate_cyc (HMM E-Value=0)
Length = 1485
Score = 82.6 bits (195), Expect = 8e-16
Identities = 43/131 (32%), Positives = 78/131 (59%), Gaps = 7/131 (5%)
Query: 304 IASQPRHEQFHK---IYIQRYENVSILFADICGFTSLSDQCTAEELVRLLNELFARFDRL 360
+A +P ++ K + + +++V+I F+DI GFTS++ Q T ++V LLN+L+ RFD++
Sbjct: 966 LAKRPIADELKKGNPVSAESFQSVTIFFSDIVGFTSVAAQSTPLQVVDLLNQLYTRFDKV 1025
Query: 361 AAEHHCLRIKLLGDCYYCVSGLPEARDD-HAKCCVEMGLDMIDAIA--LVREVMAVNVNM 417
EH +++ +GD Y VSGLP + HA M L+++ + + + + V +
Sbjct: 1026 VDEHDVYKVETIGDAYMVVSGLPVRNGERHAGEVASMALNLLSEVRDFQIPHIPSRKVQL 1085
Query: 418 RVGIHTG-RVH 427
R+GIH+ R+H
Sbjct: 1086 RIGIHSALRIH 1096
>SB_58458| Best HMM Match : Guanylate_cyc (HMM E-Value=1.2e-36)
Length = 1065
Score = 77.0 bits (181), Expect = 4e-14
Identities = 52/160 (32%), Positives = 79/160 (49%), Gaps = 11/160 (6%)
Query: 315 KIYIQRYENVSILFADICGFTSLSDQCTAEELVRLLNELFARFDRLAAEHHCLRIKLLGD 374
++ + ++ VSI F+DI GFTSLS + T ++V LLN+L+ FD + + +++ +GD
Sbjct: 747 QVTAENFDEVSIFFSDIVGFTSLSSESTPLQVVDLLNDLYTLFDEIINNYDVYKVETIGD 806
Query: 375 CYYCVSGLP-EARDDHAKCCVEMGLDMIDAI--ALVREVMAVNVNMRVGIHTGRVHCVVL 431
Y VSGLP HA M L M+ I +R + +R+GIH+G VV
Sbjct: 807 AYMVVSGLPIRNGHQHAGEIATMALHMLREIDSFKIRHRPNDKLKLRIGIHSG---MVVS 863
Query: 432 GLRKWQFDVWSNDVTLANYMESGGVAGRVHITKETLCCLG 471
G F V+ A + ES + H + L C G
Sbjct: 864 G-----FSVFCAKYPSAYFKESFNIRDLWHKRRRALVCSG 898
>SB_58457| Best HMM Match : Guanylate_cyc (HMM E-Value=0)
Length = 410
Score = 75.4 bits (177), Expect = 1e-13
Identities = 40/117 (34%), Positives = 68/117 (58%), Gaps = 4/117 (3%)
Query: 319 QRYENVSILFADICGFTSLSDQCTAEELVRLLNELFARFDRLAAEHHCLRIKLLGDCYYC 378
+ + VSI F+DI GFT LS + + ++V LLN+L+ FD + E+ +++ +GD Y
Sbjct: 124 ESFHEVSIYFSDIVGFTELSAESSPLQVVSLLNDLYTLFDDIIREYDVYKVETIGDAYMV 183
Query: 379 VSGLPEARDD-HAKCCVEMGLDMIDAIA---LVREVMAVNVNMRVGIHTGRVHCVVL 431
VSGLP + HA +M L +I+A+ +VR + +RVGIH+ + +++
Sbjct: 184 VSGLPIRNGNRHAGEIAKMALHLIEAVQTEFIVRYKPTYKLKLRVGIHSDLIVLIMI 240
>SB_28889| Best HMM Match : ANF_receptor (HMM E-Value=1.1e-34)
Length = 933
Score = 72.9 bits (171), Expect = 6e-13
Identities = 44/136 (32%), Positives = 74/136 (54%), Gaps = 13/136 (9%)
Query: 291 VLPRHVAMEMKADIASQPRHEQFHKIYIQRYENVSILFADICGFTSLSDQCTAEELVRLL 350
+LPR++A +K +P + + Y +V+I F+DI GFT L+ T ++V LL
Sbjct: 736 MLPRYIAESLKR---GEP-------VIAESYSSVTIFFSDIVGFTELAAASTPLQVVDLL 785
Query: 351 NELFARFDRLAAEHHCLRIKLLGDCYYCVSGLPEARDD-HAKCCVEMGLDMIDAIALVRE 409
N+L+ FD + +H +++ +GD Y VSGLP HA M L+++ ++ R
Sbjct: 786 NDLYTCFDTIIDKHDVYKVETIGDAYMVVSGLPVRNGHRHAGEIATMALNLLSSMGNFRA 845
Query: 410 VMAVN--VNMRVGIHT 423
N +++R+GIHT
Sbjct: 846 RHLPNRPIHLRIGIHT 861
>SB_24605| Best HMM Match : HNOB (HMM E-Value=0)
Length = 676
Score = 71.7 bits (168), Expect = 1e-12
Identities = 34/92 (36%), Positives = 56/92 (60%), Gaps = 1/92 (1%)
Query: 319 QRYENVSILFADICGFTSLSDQCTAEELVRLLNELFARFDRLAAEHHCLRIKLLGDC-YY 377
Q ++ ++LF+ + GFTS+ + A + V L+N LF +FD L +H+ + + LGD Y
Sbjct: 497 QEFDAATVLFSYMDGFTSICTRLNAMQAVTLINNLFIKFDLLTEKHNVYKFETLGDALYM 556
Query: 378 CVSGLPEARDDHAKCCVEMGLDMIDAIALVRE 409
VSG+P + HA+ M LDM+ A+ LV++
Sbjct: 557 AVSGVPVRTEHHAEPMAAMALDMLKAVQLVKD 588
>SB_35409| Best HMM Match : Guanylate_cyc (HMM E-Value=1.7e-17)
Length = 577
Score = 68.5 bits (160), Expect = 1e-11
Identities = 38/135 (28%), Positives = 69/135 (51%), Gaps = 7/135 (5%)
Query: 295 HVAMEMKADIASQPRHEQFHKIYIQRYENVSILFADICGFTSLSDQCTAEELVRLLNELF 354
H+ + + +A Q + + + + ++ V+I F+D+ F L+ T E+V LLN+L+
Sbjct: 411 HIFLSHFSSVADQLKRGK--SVVPELFDEVTIYFSDVVAFMDLASDSTPMEIVTLLNDLY 468
Query: 355 ARFDRLAAEHHCLRIKLLGDCYYCVSGLPEARD---DHAKCCVEMGLDMIDAIA--LVRE 409
D++ A H +++ +GDC VSGLP HA M LD++ + V
Sbjct: 469 IALDKILANHDVYKVESIGDCLLVVSGLPVRNGICIRHAGEIATMALDILSLMTHFKVHH 528
Query: 410 VMAVNVNMRVGIHTG 424
+ + +RVG+H+G
Sbjct: 529 RPQMKLQLRVGLHSG 543
>SB_58488| Best HMM Match : Guanylate_cyc (HMM E-Value=2.5e-31)
Length = 232
Score = 67.7 bits (158), Expect = 2e-11
Identities = 36/112 (32%), Positives = 56/112 (50%), Gaps = 3/112 (2%)
Query: 319 QRYENVSILFADICGFTSLSDQCTAEELVRLLNELFARFDRLAAEHHCLRIKLLGDCYYC 378
+ +E V+I F+DI GFT L T E+V LN L+ FD + +++ +GD Y
Sbjct: 14 EEFEEVTIFFSDIVGFTKLCSNSTPLEVVDFLNSLYVAFDEIITRFDVYKVETIGDAYMV 73
Query: 379 VSGLPEARD-DHAKCCVEMGLDMIDAIAL--VREVMAVNVNMRVGIHTGRVH 427
VSG P HA M LD++ + + +R + +R+GI+T H
Sbjct: 74 VSGCPVLNSIQHAAEIASMALDLMSHMTVFRIRHRPEDQLQLRIGINTAPGH 125
>SB_29094| Best HMM Match : Guanylate_cyc (HMM E-Value=7.9e-07)
Length = 235
Score = 49.2 bits (112), Expect = 9e-06
Identities = 27/66 (40%), Positives = 41/66 (62%), Gaps = 2/66 (3%)
Query: 415 VNMRVGIHTGRVHCVVLGLRKWQFDVWSNDVTLANYMESGGVAGRVHITKET--LCCLGD 472
+ +R+GIHTG V V+G + ++ ++ N VTLAN MESG GR++I+ +T L
Sbjct: 16 LKIRIGIHTGPVMPGVVGKKMPRYCLFGNTVTLANKMESGSQPGRINISIDTKRLLMNTS 75
Query: 473 DYKVEP 478
+Y EP
Sbjct: 76 EYDFEP 81
>SB_1188| Best HMM Match : Guanylate_cyc (HMM E-Value=6.7)
Length = 215
Score = 48.8 bits (111), Expect = 1e-05
Identities = 23/67 (34%), Positives = 41/67 (61%), Gaps = 2/67 (2%)
Query: 303 DIASQPRHEQFHKIYIQRYENVSILFADICGFTSLSDQCTAEELVRLLNELFARFDRLAA 362
D+A Q + Q I + +++V+I F+DI FT+L+ + T E+V LLN+L+ FD++
Sbjct: 148 DVAEQLKQGQ--PITAESFDSVTIFFSDIVSFTTLASESTPLEVVNLLNDLYTCFDKIID 205
Query: 363 EHHCLRI 369
H ++
Sbjct: 206 SHDVYKV 212
>SB_11487| Best HMM Match : Guanylate_cyc (HMM E-Value=2.3e-06)
Length = 360
Score = 46.4 bits (105), Expect = 6e-05
Identities = 23/86 (26%), Positives = 46/86 (53%), Gaps = 3/86 (3%)
Query: 343 AEELVRLLNELFARFDRLAAEHHCLRIKLLGDCYYCVSGLPEAR-DDHAKCCVEMGLDMI 401
A+++V LN L+ FD + + + +++ +GD Y VSG P + HA M L+++
Sbjct: 256 AQQVVEFLNILYVAFDEIITQFNVYKVETIGDAYMVVSGCPVLNGNQHAAEIASMALELL 315
Query: 402 DAIAL--VREVMAVNVNMRVGIHTGR 425
+ + + + +R+GI+TG+
Sbjct: 316 SHMTVFHIPHQPHDQLQLRIGINTGK 341
>SB_13681| Best HMM Match : Guanylate_cyc (HMM E-Value=2.8e-27)
Length = 517
Score = 44.0 bits (99), Expect = 3e-04
Identities = 29/104 (27%), Positives = 51/104 (49%), Gaps = 4/104 (3%)
Query: 357 FDRLAAEHHCLRIKLLGDCYYCVSGLPEARD-DHAKCCVEMGLDMI---DAIALVREVMA 412
FD ++ +++ +GD Y VSGLP HA M LD++ + L
Sbjct: 356 FDDHIEKYDVYKVETIGDAYMVVSGLPLRNGTSHADEIGRMSLDLVRLTETTTLDSVPKG 415
Query: 413 VNVNMRVGIHTGRVHCVVLGLRKWQFDVWSNDVTLANYMESGGV 456
+ +RVGIHTG V+G + ++ ++ + V A+ M++ G+
Sbjct: 416 KKLMVRVGIHTGPCVSGVVGYKMPRYCLFGDTVNTASRMQTTGI 459
>SB_29093| Best HMM Match : HNOBA (HMM E-Value=0)
Length = 694
Score = 43.2 bits (97), Expect = 6e-04
Identities = 24/82 (29%), Positives = 47/82 (57%), Gaps = 12/82 (14%)
Query: 290 SVLPRHVAMEMKADIASQPRHEQFHKIYIQRYENVSILFADICGFTSL--SDQCTAEELV 347
S+LP+ VA +++ + + + Y+ V+ILF+DI GFT+L +D+ ++V
Sbjct: 604 SILPKEVAAKLRLN----------QSVPAESYKTVTILFSDIVGFTALCSNDKIVPMDIV 653
Query: 348 RLLNELFARFDRLAAEHHCLRI 369
++LN L+ FD L+ + ++
Sbjct: 654 KMLNRLYTYFDMLSGMNDVYKV 675
>SB_18463| Best HMM Match : Guanylate_cyc (HMM E-Value=1.5)
Length = 71
Score = 40.7 bits (91), Expect = 0.003
Identities = 14/62 (22%), Positives = 38/62 (61%)
Query: 315 KIYIQRYENVSILFADICGFTSLSDQCTAEELVRLLNELFARFDRLAAEHHCLRIKLLGD 374
K+ + +++V++ F+DI FT++ + + ++LN++++ FD ++ +++ +GD
Sbjct: 8 KVPSEHFDSVTVFFSDIVDFTNMCAMISPMSVTQMLNDVYSVFDDHIEKYDVYKVETIGD 67
Query: 375 CY 376
Y
Sbjct: 68 AY 69
>SB_50731| Best HMM Match : Guanylate_cyc (HMM E-Value=0.76)
Length = 64
Score = 39.1 bits (87), Expect = 0.009
Identities = 16/36 (44%), Positives = 27/36 (75%)
Query: 430 VLGLRKWQFDVWSNDVTLANYMESGGVAGRVHITKE 465
V+G++K ++DV+ + V +A+ MES GV R+HI+ E
Sbjct: 7 VVGIKKPRYDVFGDTVNVASRMESNGVPNRIHISAE 42
>SB_51348| Best HMM Match : No HMM Matches (HMM E-Value=.)
Length = 68
Score = 35.1 bits (77), Expect = 0.15
Identities = 11/44 (25%), Positives = 30/44 (68%)
Query: 315 KIYIQRYENVSILFADICGFTSLSDQCTAEELVRLLNELFARFD 358
K+ + ++NV++ F DI FT++ ++ ++++LN++++ +D
Sbjct: 15 KVPSEYFDNVTVFFCDIVNFTNMCAMMSSMSVIQMLNDVYSIYD 58
>SB_48593| Best HMM Match : 7tm_1 (HMM E-Value=4.2039e-45)
Length = 341
Score = 34.3 bits (75), Expect = 0.27
Identities = 34/138 (24%), Positives = 63/138 (45%), Gaps = 10/138 (7%)
Query: 130 VIVLGLSALVFACLLACLSRP---AMNEIYL-LTISYVVLVAFLLIEFSFAGTSVLRSLT 185
V V+G++ + CL+ L++P MN + + L IS ++L+ F F F G
Sbjct: 16 VTVIGVTGNILVCLVVLLNKPMRTPMNYLLVNLAISDLLLLIFFSPTFIFKGAYTHPGGL 75
Query: 186 VSTGACSLFTYVTYATLPVRLHEATIGGLAL----AAVNIGAHLLLDNSSDMQLYCTIAT 241
CSL T ++A + + +A+ A N ++L+ +S++++ +
Sbjct: 76 AGDVLCSLVTGESFAWMGGYASALFLVAIAIERFYAVTNPHSNLVSITNSNLKILVVVCW 135
Query: 242 L--IACNAAGMLTHQPRE 257
L IA NA G + + E
Sbjct: 136 LFAIAWNAIGFIVKRYNE 153
>SB_21756| Best HMM Match : No HMM Matches (HMM E-Value=.)
Length = 52
Score = 31.1 bits (67), Expect = 2.5
Identities = 16/49 (32%), Positives = 25/49 (51%), Gaps = 4/49 (8%)
Query: 316 IYIQRYENVSILFADICGFTSLSDQCTAE----ELVRLLNELFARFDRL 360
+Y Y+ VS++FA I F+ + E +RLLNE+ FD +
Sbjct: 2 LYSHSYKRVSVMFASIPNFSEFYSEDNINNGGVECIRLLNEVITDFDEV 50
>SB_23414| Best HMM Match : Tetraspannin (HMM E-Value=3.8e-08)
Length = 357
Score = 30.7 bits (66), Expect = 3.3
Identities = 11/48 (22%), Positives = 26/48 (54%), Gaps = 1/48 (2%)
Query: 128 INVIVLGLSALVFACLLACLSRPAMNEIYLLTISYVVLVAFLLIEFSF 175
+ V++ G ++ + C L C +P++ ++ S+V+ + F +I F
Sbjct: 101 LTVVIFGAASFIL-CTLGCSRKPSIKQLRFYRSSFVIFITFEIIVMVF 147
>SB_10801| Best HMM Match : No HMM Matches (HMM E-Value=.)
Length = 910
Score = 30.7 bits (66), Expect = 3.3
Identities = 24/77 (31%), Positives = 40/77 (51%), Gaps = 4/77 (5%)
Query: 123 RVAHIINVIVLGLSALVFACLLACLSRPAMNEIYLLTISYVVL-VAFLLIEFSFAGTSVL 181
R + ++ VLGL ++ A + + + A+ + +S++V VA LL S+A S
Sbjct: 25 RCMDLFDLTVLGLGGMLDAGIYVVIGQLAIVAGPSVIVSFLVATVAALLAGLSYAELS-- 82
Query: 182 RSLTVSTGACSLFTYVT 198
S TG+ +FTYVT
Sbjct: 83 -SRITKTGSAYVFTYVT 98
>SB_54104| Best HMM Match : PolyA_pol (HMM E-Value=1.29998e-41)
Length = 466
Score = 29.5 bits (63), Expect = 7.6
Identities = 35/137 (25%), Positives = 54/137 (39%), Gaps = 15/137 (10%)
Query: 319 QRYENVSILFADICGFTSLSDQCTAEELVRLLNELFARFDRLAAEHHCLRIKLLG----D 374
+R E +IL AD GF ++ EL+RL + L +R L+G D
Sbjct: 51 RRMEGKTIL-ADTEGFKAIH----TPELLRLSSVFTKHGYELRIVGGAVRDLLMGKLPKD 105
Query: 375 CYYCVSGLPEA-----RDDHAKCCVEMGLDMIDAIALVREVMAVNVNMRVGIHTGRVHCV 429
C + PE +D+ +C +E GL A + + +R+ + T H
Sbjct: 106 IDLCTNATPEQMIKMFKDEEIRC-IETGLQHGTLTAHINKTDFEVTTLRIDVETDGRHAK 164
Query: 430 VLGLRKWQFDVWSNDVT 446
V WQ D D+T
Sbjct: 165 VKFTNDWQLDAERRDLT 181
>SB_42324| Best HMM Match : No HMM Matches (HMM E-Value=.)
Length = 523
Score = 29.5 bits (63), Expect = 7.6
Identities = 12/43 (27%), Positives = 24/43 (55%)
Query: 377 YCVSGLPEARDDHAKCCVEMGLDMIDAIALVREVMAVNVNMRV 419
+ V+G+P+ C+++G DM+ AI+L E ++ R+
Sbjct: 249 FIVAGIPQPLGTITILCIDLGTDMVPAISLAYEEAESDIMKRM 291
>SB_27050| Best HMM Match : Pkinase_Tyr (HMM E-Value=1e-06)
Length = 571
Score = 29.5 bits (63), Expect = 7.6
Identities = 15/43 (34%), Positives = 26/43 (60%), Gaps = 2/43 (4%)
Query: 303 DIASQPRHEQFHKIYIQRYENVSILFADICGFTSLSDQCTAEE 345
D+A Q + Q I + +++V+I F+DI FT+L+ + T E
Sbjct: 531 DVAEQLKQGQ--PITAESFDSVTIFFSDIVSFTTLASESTPLE 571
>SB_11543| Best HMM Match : Synaptobrevin (HMM E-Value=0.00034)
Length = 629
Score = 29.5 bits (63), Expect = 7.6
Identities = 16/50 (32%), Positives = 26/50 (52%)
Query: 217 AAVNIGAHLLLDNSSDMQLYCTIATLIACNAAGMLTHQPRELAQRRAFLE 266
A V++G + DN S + I NAA M++HQ ++ A +A L+
Sbjct: 385 AGVSLGNRRMSDNMSGNGMPDLQNNYIDLNAAAMISHQRQQAAANKAILD 434
>SB_59669| Best HMM Match : No HMM Matches (HMM E-Value=.)
Length = 3511
Score = 29.1 bits (62), Expect = 10.0
Identities = 25/81 (30%), Positives = 38/81 (46%), Gaps = 3/81 (3%)
Query: 307 QPRHEQFHKIYIQRYENVSILFADICGFTSLSDQCTAEELVRLLNELFARFDRLAAEHHC 366
+P+ ++ H+ Q E +IL ++D+ EEL R +E A+ + L A+
Sbjct: 2554 EPKKQRLHQATAQLEEKQAILAEAKAKLKEVTDRM--EELKRQYDEKSAQKEELRAKAEL 2611
Query: 367 LRIKLLGDCYYCVSGLPEARD 387
L IK L VSGL RD
Sbjct: 2612 LEIK-LDRAGKLVSGLAGERD 2631
Database: nematostella
Posted date: Oct 22, 2007 1:22 PM
Number of letters in database: 16,821,457
Number of sequences in database: 59,808
Lambda K H
0.325 0.137 0.418
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 17,211,649
Number of Sequences: 59808
Number of extensions: 637975
Number of successful extensions: 1743
Number of sequences better than 10.0: 32
Number of HSP's better than 10.0 without gapping: 22
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 1683
Number of HSP's gapped (non-prelim): 45
length of query: 566
length of database: 16,821,457
effective HSP length: 86
effective length of query: 480
effective length of database: 11,677,969
effective search space: 5605425120
effective search space used: 5605425120
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 40 (21.6 bits)
S2: 62 (29.1 bits)
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