Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA002056-TA|BGIBMGA002056-PA|IPR011072|Protein kinase
PKN/PRK1, effector
(412 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
DQ444714-1|ABE01857.1| 805|Homo sapiens cenexin 1 protein. 70 1e-11
DQ444713-1|ABE01856.1| 824|Homo sapiens cenexin 1 variant 1 pro... 70 1e-11
BC091500-1|AAH91500.1| 829|Homo sapiens ODF2 protein protein. 70 1e-11
BC010629-1|AAH10629.1| 763|Homo sapiens outer dense fiber of sp... 70 1e-11
AY366499-1|AAQ73195.1| 805|Homo sapiens outer dense fiber of sp... 70 1e-11
AL445287-6|CAH71069.1| 805|Homo sapiens outer dense fiber of sp... 70 1e-11
AL359091-23|CAI13506.1| 805|Homo sapiens outer dense fiber of s... 70 1e-11
Z11584-1|CAA77670.1| 2101|Homo sapiens NuMA protein protein. 65 5e-10
Z11583-1|CAA77669.1| 2115|Homo sapiens NuMA protein protein. 65 5e-10
BC103765-1|AAI03766.1| 691|Homo sapiens NUMA1 protein protein. 65 5e-10
BC027493-1|AAH27493.1| 691|Homo sapiens Unknown (protein for IM... 65 5e-10
AB210007-1|BAE06089.1| 2121|Homo sapiens NUMA1 variant protein p... 65 5e-10
BC012785-1|AAH12785.1| 174|Homo sapiens ODF2 protein protein. 64 7e-10
AK126816-1|BAC86706.1| 235|Homo sapiens protein ( Homo sapiens ... 63 2e-09
AF111783-1|AAD29949.1| 1939|Homo sapiens myosin heavy chain IIb ... 60 1e-08
AL445287-5|CAH71068.1| 765|Homo sapiens outer dense fiber of sp... 59 2e-08
AL359091-22|CAI13505.1| 765|Homo sapiens outer dense fiber of s... 59 2e-08
X13988-1|CAA32167.1| 1940|Homo sapiens protein ( Human mRNA for ... 58 4e-08
X13100-1|CAA31492.1| 1167|Homo sapiens myosin heavy chain (1167 ... 58 4e-08
BC126409-1|AAI26410.1| 1941|Homo sapiens myosin, heavy chain 2, ... 56 2e-07
AF111784-1|AAD29950.1| 1941|Homo sapiens myosin heavy chain IIa ... 56 2e-07
X51593-1|CAA35942.1| 1085|Homo sapiens embryonic myosin heavy ch... 56 2e-07
X15696-1|CAA33731.1| 1085|Homo sapiens protein ( Human muscle mR... 56 2e-07
M69181-1|AAA99177.1| 1976|Homo sapiens non-muscle myosin B protein. 56 2e-07
BC117691-1|AAI17692.1| 1976|Homo sapiens myosin, heavy chain 10,... 56 2e-07
BC117690-1|AAI17691.1| 1976|Homo sapiens myosin, heavy chain 10,... 56 2e-07
AB210026-1|BAE06108.1| 2018|Homo sapiens MYH10 variant protein p... 56 2e-07
X78998-1|CAA55632.1| 1411|Homo sapiens endosomal protein protein. 56 3e-07
U19769-1|AAA82889.1| 3210|Homo sapiens CENP-F kinetochore protei... 56 3e-07
AF111785-1|AAD29951.1| 1939|Homo sapiens myosin heavy chain IIx/... 56 3e-07
Z54367-1|CAA91196.1| 4684|Homo sapiens plectin protein. 55 4e-07
U63610-1|AAB05428.1| 4574|Homo sapiens plectin protein. 55 4e-07
U53204-1|AAB05427.1| 4574|Homo sapiens plectin protein. 55 4e-07
M31013-1|AAA36349.1| 1247|Homo sapiens protein ( Human nonmuscle... 55 4e-07
L40157-1|AAA79121.1| 1410|Homo sapiens endosome-associated prote... 55 4e-07
D10667-1|BAA36971.1| 1052|Homo sapiens smooth muscle myosin heav... 55 4e-07
BC114545-1|AAI14546.1| 1939|Homo sapiens myosin, heavy chain 1, ... 55 4e-07
AY480051-1|AAR95684.1| 4547|Homo sapiens plectin 11 protein. 55 4e-07
AY480050-1|AAR95683.1| 4551|Homo sapiens plectin 10 protein. 55 4e-07
AY480049-1|AAR95682.1| 4547|Homo sapiens plectin 8 protein. 55 4e-07
AY480048-1|AAR95681.1| 4515|Homo sapiens plectin 7 protein. 55 4e-07
AY480047-1|AAR95680.1| 4684|Homo sapiens plectin 6 protein. 55 4e-07
AY480046-1|AAR95679.1| 4525|Homo sapiens plectin 3 protein. 55 4e-07
AY480045-1|AAR95678.1| 4533|Homo sapiens plectin 2 protein. 55 4e-07
AY480044-1|AAR95677.1| 4574|Homo sapiens plectin 1 protein. 55 4e-07
Z82215-4|CAB05105.1| 1960|Homo sapiens myosin, heavy chain 9, no... 55 5e-07
X69292-1|CAA49154.1| 881|Homo sapiens smooth muscle mysosin he... 55 5e-07
U30872-1|AAA82935.1| 3113|Homo sapiens mitosin protein. 55 5e-07
CR456526-1|CAG30412.1| 1960|Homo sapiens MYH9 protein. 55 5e-07
AL445666-1|CAH71810.1| 3114|Homo sapiens centromere protein F, 3... 55 5e-07
AL445305-6|CAH73032.1| 3114|Homo sapiens centromere protein F, 3... 55 5e-07
AK131080-1|BAC85130.1| 563|Homo sapiens FLJ00279 protein protein. 55 5e-07
AB191263-1|BAD52439.1| 1960|Homo sapiens non-muscle myosin heavy... 55 5e-07
BC104906-1|AAI04907.1| 1938|Homo sapiens myosin, heavy chain 11,... 54 7e-07
BC101677-1|AAI01678.1| 1938|Homo sapiens myosin, heavy chain 11,... 54 7e-07
BC080545-1|AAH80545.1| 498|Homo sapiens MYH11 protein protein. 54 7e-07
BC000280-1|AAH00280.1| 471|Homo sapiens MYH10 protein protein. 54 7e-07
AY520817-1|AAS98911.1| 1945|Homo sapiens smooth muscle myosin he... 54 7e-07
AY520816-1|AAS98910.1| 1979|Homo sapiens smooth muscle myosin he... 54 7e-07
AF001548-1|AAC31665.1| 1857|Homo sapiens Myosin heavy chain (MHY... 54 7e-07
AB020673-1|BAA74889.2| 1984|Homo sapiens KIAA0866 protein protein. 54 7e-07
AY648038-1|AAT67172.1| 1551|Homo sapiens myotonic dystrophy kina... 54 1e-06
AY319414-1|AAP83847.1| 657|Homo sapiens outer dense fiber of sp... 54 1e-06
AL445287-4|CAH71067.1| 638|Homo sapiens outer dense fiber of sp... 54 1e-06
AL445287-3|CAH71066.1| 701|Homo sapiens outer dense fiber of sp... 54 1e-06
AL359091-17|CAI13500.1| 638|Homo sapiens outer dense fiber of s... 54 1e-06
AL359091-16|CAI13499.1| 701|Homo sapiens outer dense fiber of s... 54 1e-06
AF053970-1|AAC08409.1| 610|Homo sapiens outer dense fiber prote... 54 1e-06
AF012549-1|AAB66337.1| 638|Homo sapiens outer dense fiber prote... 54 1e-06
AY517555-1|AAT44528.1| 941|Homo sapiens hypothetical rhabdomyos... 52 3e-06
AF020091-1|AAB69327.1| 622|Homo sapiens smooth muscle myosin he... 52 3e-06
AF013570-1|AAB69326.1| 588|Homo sapiens smooth muscle myosin he... 52 3e-06
U25725-1|AAA86889.1| 1017|Homo sapiens AH antigen protein. 52 4e-06
AB019691-1|BAA78718.1| 3899|Homo sapiens Centrosome- and Golgi-l... 52 5e-06
X66397-1|CAA47021.1| 2349|Homo sapiens Tpr protein. 51 6e-06
U69668-1|AAB48030.1| 2363|Homo sapiens Tpr protein. 51 6e-06
L09190-1|AAA65582.1| 1898|Homo sapiens trichohyalin protein. 51 6e-06
AL832639-1|CAD89954.1| 1331|Homo sapiens hypothetical protein pr... 51 6e-06
AL596220-1|CAI13119.1| 2363|Homo sapiens translocated promoter r... 51 6e-06
AL133553-3|CAI17859.1| 2363|Homo sapiens translocated promoter r... 51 6e-06
AK027863-1|BAB55415.1| 612|Homo sapiens protein ( Homo sapiens ... 51 6e-06
U43195-1|AAB02814.1| 1354|Homo sapiens Rho-associated, coiled-co... 50 1e-05
BC113114-1|AAI13115.1| 1354|Homo sapiens Rho-associated, coiled-... 50 1e-05
AL133324-2|CAI19310.2| 1983|Homo sapiens myosin, heavy chain 7B,... 50 1e-05
AL132825-6|CAI43047.2| 1983|Homo sapiens myosin, heavy chain 7B,... 50 1e-05
AB208965-1|BAD92202.1| 705|Homo sapiens Rho-associated, coiled-... 50 1e-05
BX284668-3|CAH70057.1| 1898|Homo sapiens ciliary rootlet coiled-... 50 2e-05
BX284668-2|CAH70055.1| 2017|Homo sapiens ciliary rootlet coiled-... 50 2e-05
BC126912-1|AAI26913.1| 1132|Homo sapiens CROCC protein protein. 50 2e-05
BC126911-1|AAI26912.1| 1132|Homo sapiens CROCC protein protein. 50 2e-05
AL049569-4|CAI20365.1| 1898|Homo sapiens ciliary rootlet coiled-... 50 2e-05
AL049569-3|CAI20363.1| 2017|Homo sapiens ciliary rootlet coiled-... 50 2e-05
AB007914-1|BAA32290.2| 1919|Homo sapiens KIAA0445 protein protein. 50 2e-05
BC127772-1|AAI27773.1| 863|Homo sapiens KIF5C protein protein. 49 3e-05
BC110287-1|AAI10288.1| 725|Homo sapiens KIF5C protein protein. 49 3e-05
AY610514-1|AAT37906.1| 1302|Homo sapiens paracingulin protein. 49 3e-05
AL355355-6|CAI16549.1| 577|Homo sapiens optineurin protein. 49 3e-05
AL355355-5|CAI16550.1| 571|Homo sapiens optineurin protein. 49 3e-05
AL136382-2|CAI23514.1| 636|Homo sapiens novel protein protein. 49 3e-05
AF083322-1|AAC32373.1| 994|Homo sapiens centriole associated pr... 49 3e-05
AC108512-1|AAX82030.1| 684|Homo sapiens unknown protein. 49 3e-05
AB033055-1|BAA86543.1| 696|Homo sapiens KIAA1229 protein protein. 49 3e-05
AB011103-1|BAA25457.2| 999|Homo sapiens KIAA0531 protein protein. 49 3e-05
BC132784-1|AAI32785.1| 1116|Homo sapiens ELKS/RAB6-interacting/C... 49 3e-05
BC132782-1|AAI32783.1| 1116|Homo sapiens ELKS/RAB6-interacting/C... 49 3e-05
BC118918-1|AAI18919.1| 1302|Homo sapiens cingulin-like 1 protein. 49 3e-05
BC112049-1|AAI12050.1| 1302|Homo sapiens cingulin-like 1 protein. 49 3e-05
BC093827-1|AAH93827.1| 1302|Homo sapiens cingulin-like 1 protein. 49 3e-05
BC032762-1|AAH32762.1| 571|Homo sapiens OPTN protein protein. 49 3e-05
BC013876-1|AAH13876.1| 577|Homo sapiens optineurin protein. 49 3e-05
AY274808-1|AAP42073.1| 1302|Homo sapiens KIAA1749 protein protein. 49 3e-05
AL589986-1|CAH70024.1| 1943|Homo sapiens trichohyalin protein. 49 3e-05
AF420373-1|AAL76329.1| 577|Homo sapiens optineurin isoform 3 pr... 49 3e-05
AF420372-1|AAL76328.1| 577|Homo sapiens optineurin isoform 2 pr... 49 3e-05
AF420371-1|AAL76327.1| 577|Homo sapiens optineurin isoform 1 pr... 49 3e-05
AF111782-1|AAD29948.1| 1938|Homo sapiens myosin heavy chain prot... 49 3e-05
AB053471-1|BAC54110.1| 1116|Homo sapiens ELKS epsilon protein. 49 3e-05
AB053470-1|BAC54109.1| 1088|Homo sapiens ELKS delta protein. 49 3e-05
AB053468-1|BAC54107.1| 992|Homo sapiens ELKS beta protein. 49 3e-05
AB029004-1|BAA83033.2| 1003|Homo sapiens KIAA1081 protein protein. 49 3e-05
X82834-1|CAA58041.1| 2185|Homo sapiens 256 kD golgin protein. 48 5e-05
U41740-1|AAC50434.1| 2230|Homo sapiens trans-Golgi p230 protein. 48 5e-05
U31906-1|AAC51791.1| 2083|Homo sapiens golgin-245 protein. 48 5e-05
BC132736-1|AAI32737.1| 1843|Homo sapiens KIAA1212 protein. 48 5e-05
BC078168-1|AAH78168.1| 887|Homo sapiens KIAA1212 protein protein. 48 5e-05
BC052988-1|AAH52988.1| 980|Homo sapiens retinoic acid induced 1... 48 5e-05
AY354204-1|AAQ63889.2| 972|Homo sapiens retinoic acid induced 1... 48 5e-05
AY317139-1|AAP84319.1| 983|Homo sapiens RAI14 isoform protein. 48 5e-05
AY165122-1|AAO39147.1| 1995|Homo sapiens myosin heavy chain prot... 48 5e-05
AL137068-5|CAI12358.1| 1773|Homo sapiens centrosomal protein 110... 48 5e-05
AL137068-2|CAM13285.1| 2325|Homo sapiens centrosomal protein 110... 48 5e-05
AK074079-1|BAB84905.1| 1793|Homo sapiens FLJ00150 protein protein. 48 5e-05
AF513978-1|AAP43846.1| 2325|Homo sapiens CENTRIOLIN protein. 48 5e-05
AF155135-1|AAF44722.1| 980|Homo sapiens novel retinal pigment e... 48 5e-05
AB201172-1|BAE44387.1| 1870|Homo sapiens girdin protein. 48 5e-05
AB125644-1|BAF44475.1| 1843|Homo sapiens PKB/Akt-binding protein... 48 5e-05
AB111886-1|BAC98374.1| 1571|Homo sapiens KIAA2034 protein protein. 48 5e-05
AB040945-1|BAA96036.2| 2010|Homo sapiens KIAA1512 protein protein. 48 5e-05
AB037755-1|BAA92572.1| 989|Homo sapiens KIAA1334 protein protein. 48 5e-05
X75304-1|CAA53052.1| 3259|Homo sapiens giantin protein. 48 6e-05
D25542-1|BAA05025.1| 3225|Homo sapiens golgi antigen gcp372 prot... 48 6e-05
AF283527-1|AAG00497.1| 577|Homo sapiens FIP2 protein. 48 6e-05
AF061034-2|AAC16047.1| 520|Homo sapiens FIP2 protein. 48 6e-05
AF061034-1|AAC16046.1| 577|Homo sapiens FIP2 protein. 48 6e-05
BC011621-1|AAH11621.1| 728|Homo sapiens hook homolog 1 (Drosoph... 48 8e-05
AL121586-4|CAB89415.1| 2442|Homo sapiens centrosomal protein 250... 48 8e-05
AL035416-6|CAI22779.1| 728|Homo sapiens hook homolog 1 (Drosoph... 48 8e-05
AJ131693-1|CAB40713.1| 3908|Homo sapiens AKAP450 protein protein. 48 8e-05
AJ010770-1|CAA09361.1| 3911|Homo sapiens Hyperion protein protein. 48 8e-05
AF049105-1|AAC07988.1| 2442|Homo sapiens centrosomal Nek2-associ... 48 8e-05
AF044923-1|AAC09298.1| 728|Homo sapiens hook1 protein protein. 48 8e-05
AF022655-1|AAC06349.1| 2442|Homo sapiens cep250 centrosome assoc... 48 8e-05
AB209996-1|BAE06078.1| 2585|Homo sapiens CENPE variant protein p... 48 8e-05
AB051536-1|BAB21840.2| 1047|Homo sapiens KIAA1749 protein protein. 48 8e-05
AB015617-1|BAA88763.1| 948|Homo sapiens ELKS protein. 48 8e-05
BC130453-1|AAI30454.1| 1726|Homo sapiens ANKRD26 protein protein. 47 1e-04
BC089391-1|AAH89391.1| 466|Homo sapiens CCDC19 protein protein. 47 1e-04
AL590560-10|CAH71107.1| 551|Homo sapiens coiled-coil domain con... 47 1e-04
AL162272-4|CAC19649.1| 1710|Homo sapiens novel protein protein. 47 1e-04
AK128577-1|BAC87508.1| 1080|Homo sapiens protein ( Homo sapiens ... 47 1e-04
AB028997-1|BAA83026.2| 1715|Homo sapiens KIAA1074 protein protein. 47 1e-04
D67035-1|BAA22586.1| 973|Homo sapiens SCP-1 protein. 47 1e-04
DQ139275-1|ABA43896.1| 1313|Homo sapiens Tax1-binding protein 2 ... 47 1e-04
BC031603-1|AAH31603.1| 422|Homo sapiens ALS2CR12 protein protein. 47 1e-04
Z20656-1|CAA79675.1| 1939|Homo sapiens cardiac alpha-myosin heav... 46 2e-04
BC132667-1|AAI32668.1| 1939|Homo sapiens myosin, heavy chain 6, ... 46 2e-04
BC114620-1|AAI14621.1| 1756|Homo sapiens periplakin protein. 46 2e-04
BC023021-1|AAH23021.1| 731|Homo sapiens golgi autoantigen, golg... 46 2e-04
AY644768-1|AAV85456.1| 731|Homo sapiens cell proliferation-indu... 46 2e-04
AF085199-1|AAD09753.1| 731|Homo sapiens golgin-84 protein. 46 2e-04
AF041004-1|AAD17459.1| 1756|Homo sapiens periplakin protein. 46 2e-04
AF013717-1|AAC39668.1| 1756|Homo sapiens periplakin protein. 46 2e-04
AF001691-1|AAC17738.1| 1756|Homo sapiens 195 kDa cornified envel... 46 2e-04
AB011140-1|BAA25494.1| 1426|Homo sapiens KIAA0568 protein protein. 46 2e-04
M77830-1|AAA85135.1| 2871|Homo sapiens desmoplakin I protein. 46 2e-04
J05211-1|AAA35766.1| 1752|Homo sapiens protein ( Human desmoplak... 46 2e-04
BX530088-1|CAI95784.1| 810|Homo sapiens GRIP1 associated protei... 46 2e-04
AL031058-1|CAA19927.1| 2871|Homo sapiens desmoplakin protein. 46 2e-04
X52889-1|CAA37068.1| 1934|Homo sapiens cardiac beta myosin heavy... 46 3e-04
X51591-1|CAA35940.1| 1151|Homo sapiens beta-myosin heavy chain (... 46 3e-04
M58018-1|AAA62830.1| 1935|Homo sapiens beta-myosin heavy chain p... 46 3e-04
M57965-1|AAA51837.1| 1935|Homo sapiens beta-myosin heavy chain p... 46 3e-04
M25139-1|AAA60385.1| 611|Homo sapiens myosin heavy chain beta-s... 46 3e-04
EF179180-1|ABN05283.1| 1935|Homo sapiens myosin, heavy chain 7, ... 46 3e-04
BC112173-1|AAI12174.1| 1935|Homo sapiens myosin, heavy chain 7, ... 46 3e-04
BC112171-1|AAI12172.1| 1935|Homo sapiens myosin, heavy chain 7, ... 46 3e-04
BC007570-1|AAH07570.1| 649|Homo sapiens FBF1 protein protein. 46 3e-04
AY518538-1|AAT44534.1| 1179|Homo sapiens rhabdomyosarcoma antige... 46 3e-04
AL136382-1|CAI23513.1| 620|Homo sapiens novel protein protein. 46 3e-04
AJ238393-1|CAC20413.1| 1935|Homo sapiens beta-myosin heavy chain... 46 3e-04
AF112218-1|AAF17206.1| 742|Homo sapiens unknown protein. 46 3e-04
AB209708-1|BAD92945.1| 1574|Homo sapiens myosin, heavy polypepti... 46 3e-04
M36769-1|AAC17185.1| 1937|Homo sapiens perinatal myosin heavy ch... 45 4e-04
BC130564-1|AAI30565.1| 905|Homo sapiens KIAA1524 protein. 45 4e-04
AL365436-2|CAI16590.1| 1203|Homo sapiens cingulin protein. 45 4e-04
AL132765-6|CAC10587.1| 977|Homo sapiens ribosome binding protei... 45 4e-04
AL132765-4|CAH74034.1| 1410|Homo sapiens ribosome binding protei... 45 4e-04
AK093227-1|BAC04102.1| 550|Homo sapiens protein ( Homo sapiens ... 45 4e-04
AK022912-1|BAB14305.1| 472|Homo sapiens protein ( Homo sapiens ... 45 4e-04
AF334474-1|AAL11632.1| 905|Homo sapiens p90 autoantigen protein. 45 4e-04
AF263462-1|AAF74498.1| 1203|Homo sapiens cingulin protein. 45 4e-04
AB040957-1|BAA96048.1| 884|Homo sapiens KIAA1524 protein protein. 45 4e-04
AB037740-1|BAA92557.1| 1208|Homo sapiens KIAA1319 protein protein. 45 4e-04
AB033102-1|BAA86590.1| 1068|Homo sapiens KIAA1276 protein protein. 45 4e-04
AB023217-1|BAA76844.2| 1956|Homo sapiens KIAA1000 protein protein. 45 4e-04
D00943-1|BAA00791.1| 1939|Homo sapiens cardiac alpha-myosin heav... 45 6e-04
BC040232-1|AAH40232.1| 696|Homo sapiens CCDC88 protein protein. 45 6e-04
BC032853-1|AAH32853.1| 767|Homo sapiens golgi autoantigen, golg... 45 6e-04
AY651261-1|AAX35689.1| 1244|Homo sapiens centrosomal protein 1 p... 45 6e-04
AB209115-1|BAD92352.1| 1065|Homo sapiens restin isoform a varian... 45 6e-04
Z38133-1|CAA86293.1| 1937|Homo sapiens Myosin protein. 44 7e-04
X51592-1|CAA35941.1| 1437|Homo sapiens fetal-myosin heavy chain ... 44 7e-04
U51587-1|AAB81549.1| 767|Homo sapiens Golgi complex autoantigen... 44 7e-04
BC125086-1|AAI25087.1| 634|Homo sapiens CCDC41 protein protein. 44 7e-04
BC019577-1|AAH19577.1| 314|Homo sapiens Unknown (protein for IM... 44 7e-04
BC017659-1|AAH17659.1| 285|Homo sapiens KIAA1524 protein protein. 44 7e-04
AL451125-2|CAI14346.1| 767|Homo sapiens golgi autoantigen, golg... 44 7e-04
AL354928-1|CAI39632.1| 767|Homo sapiens golgi autoantigen, golg... 44 7e-04
AF312367-1|AAQ14554.1| 708|Homo sapiens La binding protein 1 pr... 44 7e-04
AF083037-1|AAD22767.1| 3595|Homo sapiens A-kinase anchoring prot... 44 7e-04
AC012487-1|AAX88838.1| 1583|Homo sapiens unknown protein. 44 7e-04
AB208858-1|BAD92095.1| 400|Homo sapiens golgin 97 variant protein. 44 7e-04
AB002334-1|BAA20794.2| 1635|Homo sapiens KIAA0336 protein. 44 7e-04
BC117132-1|AAI17133.1| 1306|Homo sapiens kinectin 1 (kinesin rec... 44 0.001
BC112337-1|AAI12338.1| 1306|Homo sapiens kinectin 1 (kinesin rec... 44 0.001
BC014109-1|AAH14109.1| 670|Homo sapiens leucine rich repeat con... 44 0.001
AL137068-6|CAI12359.1| 346|Homo sapiens centrosomal protein 110... 44 0.001
Y12490-1|CAA73095.1| 1979|Homo sapiens Golgi-associated microtub... 44 0.001
X03541-1|CAA27243.1| 641|Homo sapiens protein ( Human mRNA of t... 44 0.001
U52962-1|AAD10838.1| 3321|Homo sapiens kendrin protein. 44 0.001
BC128578-1|AAI28579.1| 751|Homo sapiens RRBP1 protein protein. 44 0.001
BC113409-1|AAI13410.1| 1416|Homo sapiens uveal autoantigen with ... 44 0.001
BC113407-1|AAI13408.1| 1416|Homo sapiens uveal autoantigen with ... 44 0.001
BC016881-1|AAH16881.1| 638|Homo sapiens Unknown (protein for IM... 44 0.001
AL590642-2|CAH70770.1| 862|Homo sapiens CDK5 regulatory subunit... 44 0.001
AL590642-1|CAH70769.1| 1893|Homo sapiens CDK5 regulatory subunit... 44 0.001
AL391870-2|CAI40925.1| 1893|Homo sapiens CDK5 regulatory subunit... 44 0.001
AL391870-1|CAI40926.1| 862|Homo sapiens CDK5 regulatory subunit... 44 0.001
AL353736-2|CAI40654.1| 862|Homo sapiens CDK5 regulatory subunit... 44 0.001
AL353736-1|CAI40653.1| 1893|Homo sapiens CDK5 regulatory subunit... 44 0.001
AL138836-2|CAI16963.1| 1893|Homo sapiens CDK5 regulatory subunit... 44 0.001
AL138836-1|CAI16964.1| 862|Homo sapiens CDK5 regulatory subunit... 44 0.001
AK055435-1|BAB70922.1| 634|Homo sapiens protein ( Homo sapiens ... 44 0.001
AF515282-1|AAP46636.1| 3336|Homo sapiens pericentrin B protein. 44 0.001
AF448860-1|AAP41926.1| 1893|Homo sapiens hypothetical protein pr... 44 0.001
AF322916-1|AAG49577.1| 1416|Homo sapiens uveal autoantigen protein. 44 0.001
AF155115-1|AAD42881.1| 472|Homo sapiens NY-REN-58 antigen protein. 44 0.001
AF091711-1|AAD39719.1| 1773|Homo sapiens splice variant AKAP350 ... 44 0.001
AF006751-1|AAC25977.1| 977|Homo sapiens ES/130 protein. 44 0.001
AC004013-1|AAB96867.2| 2058|Homo sapiens unknown protein. 44 0.001
AB046781-1|BAB13387.2| 1416|Homo sapiens KIAA1561 protein protein. 44 0.001
AB018346-1|BAA34523.1| 1708|Homo sapiens KIAA0803 protein protein. 44 0.001
AB007862-1|BAA23698.3| 3284|Homo sapiens KIAA0402 protein. 44 0.001
Z22551-1|CAA80271.1| 1356|Homo sapiens 156 kDa Protein protein. 43 0.002
L25616-1|AAB65853.1| 1300|Homo sapiens kinectin protein. 43 0.002
D13629-1|BAA02794.2| 1307|Homo sapiens KIAA0004 protein. 43 0.002
BC060803-1|AAH60803.1| 715|Homo sapiens chromosome 6 open readi... 43 0.002
BC007808-1|AAH07808.1| 1006|Homo sapiens MYH7B protein protein. 43 0.002
AY264265-1|AAP20418.1| 1357|Homo sapiens kinectin variant 1 prot... 43 0.002
AK026958-1|BAB15602.1| 715|Homo sapiens protein ( Homo sapiens ... 43 0.002
AF263742-1|AAF72196.1| 693|Homo sapiens golgin-like protein pro... 43 0.002
BX538093-1|CAD98012.1| 1732|Homo sapiens hypothetical protein pr... 43 0.002
BX537708-1|CAD97819.1| 1605|Homo sapiens hypothetical protein pr... 43 0.002
BX537421-1|CAD97663.1| 1204|Homo sapiens hypothetical protein pr... 43 0.002
BC141866-1|AAI41867.1| 1240|Homo sapiens Unknown (protein for IM... 43 0.002
BC131805-1|AAI31806.1| 913|Homo sapiens CCDC46 protein protein. 43 0.002
BC128577-1|AAI28578.1| 934|Homo sapiens RRBP1 protein protein. 43 0.002
BC050555-1|AAH50555.1| 873|Homo sapiens KTN1 protein protein. 43 0.002
BC039612-1|AAH39612.1| 2002|Homo sapiens MYO18A protein protein. 43 0.002
BC012003-1|AAH12003.1| 365|Homo sapiens CEP135 protein protein. 43 0.002
BC011615-1|AAH11615.2| 739|Homo sapiens AZI1 protein protein. 43 0.002
BC000099-1|AAH00099.4| 655|Homo sapiens RRBP1 protein protein. 43 0.002
AL137068-7|CAD20123.1| 1007|Homo sapiens centrosomal protein 110... 43 0.002
AF527734-1|AAP85633.1| 439|Homo sapiens medulloblastoma antigen... 43 0.002
AB209693-1|BAD92930.1| 1310|Homo sapiens golgi autoantigen, golg... 43 0.002
AB046853-1|BAB13459.2| 1852|Homo sapiens KIAA1633 protein protein. 43 0.002
AB037819-1|BAA92636.2| 1586|Homo sapiens KIAA1398 protein protein. 43 0.002
AB029041-1|BAA83070.1| 1165|Homo sapiens KIAA1118 protein protein. 43 0.002
Z29064-1|CAA82305.1| 896|Homo sapiens AF-1p protein. 42 0.003
Y19210-1|CAB76830.1| 507|Homo sapiens type II hair keratin 5 pr... 42 0.003
U07707-1|AAA52101.1| 896|Homo sapiens epidermal growth factor r... 42 0.003
DQ367924-1|ABD34786.1| 896|Homo sapiens epidermal growth factor... 42 0.003
CR533567-1|CAG38598.1| 691|Homo sapiens KIAA1536 protein. 42 0.003
BX537759-1|CAD97828.1| 1763|Homo sapiens hypothetical protein pr... 42 0.003
BC129803-1|AAI29804.1| 638|Homo sapiens MYH14 protein protein. 42 0.003
BC127816-1|AAI27817.1| 416|Homo sapiens Unknown (protein for IM... 42 0.003
BC069268-1|AAH69268.1| 990|Homo sapiens golgi autoantigen, golg... 42 0.003
AY528715-1|AAT44400.1| 1016|Homo sapiens antigen MU-RMS-40.16A p... 42 0.003
AL671986-11|CAI13030.1| 896|Homo sapiens epidermal growth facto... 42 0.003
AL590708-22|CAI13842.1| 952|Homo sapiens golgi autoantigen, gol... 42 0.003
AL590708-21|CAI13841.1| 990|Homo sapiens golgi autoantigen, gol... 42 0.003
AL449305-3|CAI10964.1| 1244|Homo sapiens FK506 binding protein 1... 42 0.003
AL449105-1|CAI95402.1| 1244|Homo sapiens FK506 binding protein 1... 42 0.003
AK075055-1|BAC11372.1| 360|Homo sapiens protein ( Homo sapiens ... 42 0.003
AF317887-1|AAK01919.1| 589|Homo sapiens monoclonal antibody 3H1... 42 0.003
AF248953-1|AAF65550.1| 990|Homo sapiens golgi matrix protein GM... 42 0.003
AB208841-1|BAD92078.1| 1585|Homo sapiens Nuclear mitotic apparat... 42 0.003
AB014574-1|BAA31649.1| 1234|Homo sapiens KIAA0674 protein protein. 42 0.003
Y15164-1|CAA75436.1| 1012|Homo sapiens Cxorf5 (71-7A) protein pr... 42 0.004
BC118982-1|AAI18983.1| 553|Homo sapiens KIAA2012 protein protein. 42 0.004
BC003177-1|AAH03177.1| 691|Homo sapiens calcium binding and coi... 42 0.004
AY563137-1|AAT68474.1| 691|Homo sapiens calphoglin protein. 42 0.004
AY358397-1|AAQ88763.1| 691|Homo sapiens EESP2436 protein. 42 0.004
AK027881-1|BAB55428.1| 690|Homo sapiens protein ( Homo sapiens ... 42 0.004
AB103610-1|BAF31272.1| 756|Homo sapiens HCR protein protein. 42 0.004
AB095932-1|BAC23108.1| 555|Homo sapiens KIAA2012 protein protein. 42 0.004
AB082528-1|BAC02706.2| 1685|Homo sapiens KIAA1997 protein protein. 42 0.004
AB040969-1|BAA96060.1| 645|Homo sapiens KIAA1536 protein protein. 42 0.004
Z15005-1|CAA78727.1| 2663|Homo sapiens CENP-E protein. 42 0.005
X65873-1|CAA46703.1| 963|Homo sapiens kinesin heavy chain protein. 42 0.005
BC126281-1|AAI26282.1| 963|Homo sapiens kinesin family member 5... 42 0.005
BC126279-1|AAI26280.1| 963|Homo sapiens kinesin family member 5... 42 0.005
BC125087-1|AAI25088.1| 568|Homo sapiens CCDC41 protein protein. 42 0.005
BC025422-1|AAH25422.1| 676|Homo sapiens cut-like 1, CCAAT displ... 42 0.005
AY491401-1|AAR83719.1| 399|Homo sapiens brain leucine zipper pr... 42 0.005
AL161932-2|CAH71618.1| 963|Homo sapiens kinesin family member 5... 42 0.005
AL137265-1|CAB70664.1| 992|Homo sapiens hypothetical protein pr... 42 0.005
AB028975-1|BAA83004.2| 1456|Homo sapiens KIAA1052 protein protein. 42 0.005
Z97832-4|CAI20190.1| 631|Homo sapiens differentially expressed ... 41 0.007
X03741-1|CAA27381.1| 635|Homo sapiens protein ( Human cardiac m... 41 0.007
CR457227-1|CAG33508.1| 782|Homo sapiens C6orf18 protein. 41 0.007
BX572623-1|CAM12862.1| 664|Homo sapiens novel protein protein. 41 0.007
BX538186-1|CAD98058.1| 971|Homo sapiens hypothetical protein pr... 41 0.007
BC032427-1|AAH32427.1| 664|Homo sapiens transmembrane protein 5... 41 0.007
AY845015-1|AAX11913.1| 664|Homo sapiens macoilin protein. 41 0.007
AY642382-1|AAV34207.1| 1135|Homo sapiens GPBP-interacting protei... 41 0.007
AY241694-1|AAO91767.1| 631|Homo sapiens IRF4-binding protein pr... 41 0.007
AL773544-6|CAI18483.1| 782|Homo sapiens chromosome 6 open readi... 41 0.007
AL662844-15|CAM25639.1| 871|Homo sapiens coiled-coil alpha-heli... 41 0.007
AL662844-11|CAM25635.1| 316|Homo sapiens coiled-coil alpha-heli... 41 0.007
AL662844-10|CAI18328.1| 782|Homo sapiens coiled-coil alpha-heli... 41 0.007
AL662844-9|CAM25634.1| 729|Homo sapiens coiled-coil alpha-helic... 41 0.007
AL031284-6|CAM12861.1| 664|Homo sapiens novel protein protein. 41 0.007
AK001609-1|BAA91786.1| 664|Homo sapiens protein ( Homo sapiens ... 41 0.007
AK000217-1|BAA91016.1| 782|Homo sapiens protein ( Homo sapiens ... 41 0.007
AK000204-1|BAA91007.1| 782|Homo sapiens protein ( Homo sapiens ... 41 0.007
AJ276095-1|CAC08450.1| 631|Homo sapiens Def-6 protein protein. 41 0.007
AF514868-1|AAQ08178.1| 1133|Homo sapiens GPBP-interacting protei... 41 0.007
AB202104-1|BAE78628.1| 756|Homo sapiens chromosome 6 open readi... 41 0.007
AB112475-1|BAD05131.1| 782|Homo sapiens StAR protein binding pr... 41 0.007
AB112474-1|BAD05130.1| 782|Homo sapiens StAR protein binding pr... 41 0.007
D87931-1|BAA75636.1| 1388|Homo sapiens Rho kinase protein. 41 0.009
D86326-1|BAA25300.1| 962|Homo sapiens p115 protein. 41 0.009
BC111801-1|AAI11802.1| 703|Homo sapiens ROCK2 protein protein. 41 0.009
BC096344-1|AAH96344.1| 972|Homo sapiens OFD1 protein protein. 41 0.009
BC071583-1|AAH71583.1| 1139|Homo sapiens DCTN1 protein protein. 41 0.009
BC062449-1|AAH62449.1| 245|Homo sapiens FLJ39660 protein protein. 41 0.009
BC032654-1|AAH32654.1| 961|Homo sapiens vesicle docking protein... 41 0.009
AY536375-1|AAT66048.1| 820|Homo sapiens rhabdomyosarcoma antige... 41 0.009
AK027300-1|BAB55025.1| 212|Homo sapiens protein ( Homo sapiens ... 41 0.009
AF115510-1|AAD41258.1| 603|Homo sapiens LRR FLI-I interacting p... 41 0.009
AC068544-1|AAY14905.1| 417|Homo sapiens unknown protein. 41 0.009
AC018463-2|AAX93049.1| 1337|Homo sapiens unknown protein. 41 0.009
AB014519-1|BAA31594.2| 1428|Homo sapiens KIAA0619 protein protein. 41 0.009
U22816-1|AAC50173.1| 1202|Homo sapiens LAR-interacting protein 1... 40 0.012
U22815-1|AAC50172.1| 1185|Homo sapiens LAR-interacting protein 1... 40 0.012
L12579-1|AAA35654.1| 678|Homo sapiens protein ( Human alternati... 40 0.012
DQ355971-1|ABC67469.1| 1711|Homo sapiens CDC42 binding protein k... 40 0.012
DQ109808-1|AAZ83370.1| 2479|Homo sapiens nephrocystin-6 protein. 40 0.012
BC112391-1|AAI12392.1| 957|Homo sapiens ELKS/RAB6-interacting/C... 40 0.012
BC111550-1|AAI11551.1| 957|Homo sapiens ERC2 protein protein. 40 0.012
BC110535-1|AAI10536.1| 782|Homo sapiens coiled-coil alpha-helic... 40 0.012
BC110534-1|AAI10535.1| 746|Homo sapiens CCHCR1 protein protein. 40 0.012
BC047871-1|AAH47871.1| 933|Homo sapiens CDC42BPB protein protein. 40 0.012
BC043398-1|AAH43398.1| 805|Homo sapiens CEP290 protein protein. 40 0.012
BA000025-61|BAB63313.1| 756|Homo sapiens Tricohyalin homologue ... 40 0.012
AY422473-1|AAR13704.1| 1326|Homo sapiens myosin tail domain-cont... 40 0.012
AL662788-1|CAI95333.1| 1326|Homo sapiens chromosome 9 open readi... 40 0.012
AL592153-1|CAI95316.1| 1326|Homo sapiens chromosome 9 open readi... 40 0.012
AL365275-1|CAI40383.1| 1140|Homo sapiens chromosome 6 open readi... 40 0.012
AL359877-3|CAI94977.1| 1326|Homo sapiens chromosome 9 open readi... 40 0.012
AL137009-1|CAI20344.1| 1140|Homo sapiens chromosome 6 open readi... 40 0.012
AL132874-2|CAI42604.1| 1140|Homo sapiens chromosome 6 open readi... 40 0.012
AK222832-1|BAD96552.1| 678|Homo sapiens CCAAT displacement prot... 40 0.012
AK125995-1|BAC86384.1| 842|Homo sapiens protein ( Homo sapiens ... 40 0.012
AK097517-1|BAC05084.1| 621|Homo sapiens protein ( Homo sapiens ... 40 0.012
AK091682-1|BAC03719.1| 936|Homo sapiens protein ( Homo sapiens ... 40 0.012
AK023943-1|BAB14735.1| 545|Homo sapiens protein ( Homo sapiens ... 40 0.012
AJ304866-1|CAC34835.1| 429|Homo sapiens A20-binding inhibitor o... 40 0.012
AF216493-1|AAF74221.1| 756|Homo sapiens a-helical protein protein. 40 0.012
AF128625-1|AAD37506.1| 1711|Homo sapiens CDC42-binding protein k... 40 0.012
AB088104-1|BAC54937.1| 756|Homo sapiens tricohyalin homologue p... 40 0.012
AB032950-1|BAA86438.2| 1760|Homo sapiens KIAA1124 protein protein. 40 0.012
AB029343-1|BAA82158.1| 756|Homo sapiens HCR protein. 40 0.012
AB014535-1|BAA31610.2| 864|Homo sapiens KIAA0635 protein protein. 40 0.012
AB002376-1|BAA20832.2| 970|Homo sapiens KIAA0378 protein. 40 0.012
Z98882-1|CAI95591.1| 756|Homo sapiens RAB11 family interacting ... 40 0.016
Y07759-2|CAA69036.1| 1828|Homo sapiens mysoin heavy chain 12 pro... 40 0.016
Y07759-1|CAA69035.1| 1855|Homo sapiens mysoin heavy chain 12 pro... 40 0.016
X98801-1|CAA67333.1| 1263|Homo sapiens dynactin protein. 40 0.016
D86958-1|BAA13194.2| 1593|Homo sapiens KIAA0203 protein. 40 0.016
BX641024-1|CAE46015.1| 1694|Homo sapiens hypothetical protein pr... 40 0.016
BX640704-1|CAE45824.1| 594|Homo sapiens hypothetical protein pr... 40 0.016
BX530088-3|CAI95786.1| 841|Homo sapiens GRIP1 associated protei... 40 0.016
BX530088-2|CAI95785.1| 796|Homo sapiens GRIP1 associated protei... 40 0.016
BC107746-1|AAI07747.1| 218|Homo sapiens Unknown (protein for IM... 40 0.016
BC101546-1|AAI01547.1| 841|Homo sapiens GRIP1 associated protei... 40 0.016
BC101544-1|AAI01545.1| 841|Homo sapiens GRIP1 associated protei... 40 0.016
BC077732-1|AAH77732.1| 662|Homo sapiens FKBP15 protein protein. 40 0.016
BC051360-1|AAH51360.1| 756|Homo sapiens RAB11 family interactin... 40 0.016
BC050434-1|AAH50434.1| 273|Homo sapiens FLJ10154 protein protein. 40 0.016
BC017556-1|AAH17556.1| 1594|Homo sapiens RB1-inducible coiled-co... 40 0.016
AY130007-1|AAN05091.1| 225|Homo sapiens MU-MB-17.148 protein. 40 0.016
AL451082-2|CAH72276.1| 1194|Homo sapiens protein tyrosine phosph... 40 0.016
AL442127-3|CAI13168.1| 273|Homo sapiens RP11-297I6.1 protein. 40 0.016
AL049542-2|CAI95788.1| 756|Homo sapiens RAB11 family interactin... 40 0.016
AL023881-3|CAI95593.1| 756|Homo sapiens RAB11 family interactin... 40 0.016
AK001016-1|BAA91467.1| 273|Homo sapiens protein ( Homo sapiens ... 40 0.016
AF395731-1|AAL12940.1| 756|Homo sapiens eferin protein. 40 0.016
AF086947-1|AAD03694.1| 1261|Homo sapiens dynactin 1 protein. 40 0.016
AF064205-2|AAD55812.1| 1144|Homo sapiens dynactin 1 p135 isoform... 40 0.016
AF064205-1|AAD55811.1| 1278|Homo sapiens dynactin 1 p150 isoform... 40 0.016
AE006463-12|AAK61232.1| 756|Homo sapiens unknown function protein. 40 0.016
AB209625-1|BAD92862.1| 459|Homo sapiens dynactin 1 isoform 1 va... 40 0.016
AB059622-1|BAB69690.1| 1594|Homo sapiens Rb1-inducible coiled co... 40 0.016
AB032993-1|BAA86481.1| 834|Homo sapiens KIAA1167 protein protein. 40 0.016
AB018345-1|BAA34522.2| 1578|Homo sapiens KIAA0802 protein protein. 40 0.016
AB014565-1|BAA31640.2| 760|Homo sapiens KIAA0665 protein protein. 40 0.016
Z22957-1|CAA80533.1| 812|Homo sapiens myosin I homologue protein. 40 0.021
X99140-1|CAA67577.1| 507|Homo sapiens type II intermediate fila... 40 0.021
X04201-1|CAA27798.1| 285|Homo sapiens protein ( Human skeletal ... 40 0.021
U90942-1|AAD00702.1| 1855|Homo sapiens myosin heavy chain 12 pro... 40 0.021
M19715-1|AAA61227.1| 229|Homo sapiens TPM1 protein. 40 0.021
M19267-1|AAA36771.1| 284|Homo sapiens protein ( Human tropomyos... 40 0.021
L01042-1|AAD54608.1| 1093|Homo sapiens TATA element modulatory f... 40 0.021
BC126123-1|AAI26124.1| 1093|Homo sapiens TATA element modulatory... 40 0.021
BC117418-1|AAI17419.1| 1093|Homo sapiens TATA element modulatory... 40 0.021
BC036380-1|AAH36380.1| 1380|Homo sapiens KIAA0980 protein protein. 40 0.021
BC013023-1|AAH13023.1| 1193|Homo sapiens NUMA1 protein protein. 40 0.021
BC008425-1|AAH08425.1| 285|Homo sapiens tropomyosin 3 protein. 40 0.021
BC008407-1|AAH08407.1| 285|Homo sapiens tropomyosin 3 protein. 40 0.021
BC000676-1|AAH00676.2| 483|Homo sapiens MYH14 protein protein. 40 0.021
AL590431-11|CAH71269.1| 284|Homo sapiens tropomyosin 3 protein. 40 0.021
AL031672-2|CAI43018.1| 1382|Homo sapiens novel protein protein. 40 0.021
AK092490-1|BAC03904.1| 280|Homo sapiens protein ( Homo sapiens ... 40 0.021
AB209505-1|BAD92742.1| 1409|Homo sapiens Myosin Va variant protein. 40 0.021
AB209487-1|BAD92724.1| 1409|Homo sapiens Myosin Va variant protein. 40 0.021
AB209109-1|BAD92346.1| 1096|Homo sapiens TATA element modulatory... 40 0.021
AB023197-1|BAA76824.1| 1406|Homo sapiens KIAA0980 protein protein. 40 0.021
D86970-1|BAA13206.2| 2067|Homo sapiens KIAA0216 protein. 39 0.028
BC117182-1|AAI17183.1| 1654|Homo sapiens CEP152 protein protein. 39 0.028
BC111395-1|AAI11396.1| 554|Homo sapiens NEXN protein protein. 39 0.028
BC107721-1|AAI07722.1| 592|Homo sapiens Unknown (protein for IM... 39 0.028
BC078665-1|AAH78665.1| 775|Homo sapiens GRIP and coiled-coil do... 39 0.028
BC069186-1|AAH69186.1| 591|Homo sapiens CEP152 protein protein. 39 0.028
BC060769-1|AAH60769.2| 1107|Homo sapiens chromosome 6 open readi... 39 0.028
BC051733-1|AAH51733.1| 1026|Homo sapiens LUZP1 protein protein. 39 0.028
BC014100-1|AAH14100.1| 775|Homo sapiens GRIP and coiled-coil do... 39 0.028
AY703984-1|AAV80770.1| 1581|Homo sapiens SP-A receptor subunit S... 39 0.028
AL031428-1|CAI19705.1| 1026|Homo sapiens leucine zipper protein ... 39 0.028
AK074153-1|BAB84979.1| 1046|Homo sapiens FLJ00226 protein protein. 39 0.028
AK025690-1|BAB15219.1| 746|Homo sapiens protein ( Homo sapiens ... 39 0.028
AF525417-1|AAM91948.1| 775|Homo sapiens Golgi coiled coil prote... 39 0.028
AF458591-1|AAM49719.1| 590|Homo sapiens hypothetical protein pr... 39 0.028
AF114264-1|AAD29607.1| 448|Homo sapiens unknown protein. 39 0.028
AB177860-1|BAD66838.1| 1715|Homo sapiens KIAA0216 splice variant... 39 0.028
AB177858-1|BAD66836.1| 2046|Homo sapiens KIAA0216 splice variant... 39 0.028
AB020719-1|BAA74935.1| 1300|Homo sapiens KIAA0912 protein protein. 39 0.028
Z98949-1|CAI17892.1| 2566|Homo sapiens protein ( Human DNA seque... 39 0.037
S67240-1|AAB28951.1| 330|Homo sapiens smooth muscle myosin heav... 39 0.037
S67238-1|AAB28950.1| 296|Homo sapiens smooth muscle myosin heav... 39 0.037
BC127957-1|AAI27958.1| 166|Homo sapiens family with sequence si... 39 0.037
BC109126-1|AAI09127.1| 872|Homo sapiens chromosome 10 open read... 39 0.037
BC036225-1|AAH36225.1| 872|Homo sapiens chromosome 10 open read... 39 0.037
BC034046-1|AAH34046.1| 1202|Homo sapiens protein tyrosine phosph... 39 0.037
BC031621-1|AAH31621.1| 401|Homo sapiens Rab interacting lysosom... 39 0.037
BC031576-1|AAH31576.1| 368|Homo sapiens F-box protein 28 protein. 39 0.037
BC028423-1|AAH28423.1| 1022|Homo sapiens PMFBP1 protein protein. 39 0.037
BC015922-1|AAH15922.1| 688|Homo sapiens trafficking protein, ki... 39 0.037
BC012568-1|AAH12568.1| 605|Homo sapiens coiled-coil domain cont... 39 0.037
BC004961-1|AAH04961.1| 348|Homo sapiens RILP protein protein. 39 0.037
AY517557-1|AAT44530.1| 605|Homo sapiens hypothetical rhabdomyos... 39 0.037
AY077700-1|AAL75811.1| 2568|Homo sapiens myosin-like protein pro... 39 0.037
AL832010-1|CAD89917.1| 973|Homo sapiens hypothetical protein pr... 39 0.037
AL390122-1|CAH70934.1| 368|Homo sapiens F-box protein 28 protein. 39 0.037
AL355378-1|CAI15667.1| 872|Homo sapiens novel protein protein. 39 0.037
AL162742-5|CAI12110.1| 872|Homo sapiens novel protein protein. 39 0.037
AL080245-1|CAI16965.1| 2566|Homo sapiens protein ( Human DNA seq... 39 0.037
AL079300-1|CAI17881.1| 2566|Homo sapiens protein ( Human DNA seq... 39 0.037
AL022329-3|CAI17968.1| 2566|Homo sapiens protein ( Human DNA seq... 39 0.037
AK055755-1|BAB71003.1| 401|Homo sapiens protein ( Homo sapiens ... 39 0.037
AK001628-1|BAA91795.1| 368|Homo sapiens RNA. protein. 39 0.037
AK000371-1|BAA91119.1| 413|Homo sapiens protein ( Homo sapiens ... 39 0.037
AJ404317-1|CAC33443.1| 401|Homo sapiens rab interacting lysosom... 39 0.037
AJ310932-1|CAC70714.3| 2567|Homo sapiens myosin heavy chain prot... 39 0.037
AJ310931-1|CAC70712.2| 2567|Homo sapiens myosin heavy chain prot... 39 0.037
AJ278711-1|CAC82174.1| 401|Homo sapiens hypothetical protein pr... 39 0.037
AF494345-1|AAN07164.1| 166|Homo sapiens family with sequence si... 39 0.037
AF485338-1|AAL93149.1| 1498|Homo sapiens golgin-160 protein. 39 0.037
AF007217-1|AAD09135.1| 1978|Homo sapiens Trip230 protein. 39 0.037
AB075376-1|BAC16363.1| 2567|Homo sapiens bk125H2.1 protein. 39 0.037
AB053469-1|BAC54108.1| 720|Homo sapiens ELKS gamma protein. 39 0.037
AB042648-1|BAB55550.2| 2080|Homo sapiens bk125H2.1 protein. 39 0.037
AB028965-1|BAA82994.2| 1019|Homo sapiens KIAA1042 protein protein. 39 0.037
AB007952-1|BAA32327.1| 299|Homo sapiens KIAA0483 protein protein. 39 0.037
Z22664-1|CAA80377.1| 595|Homo sapiens membrane organizing prote... 38 0.049
Y18000-2|CAA76993.1| 615|Homo sapiens NF2 protein protein. 38 0.049
Y18000-1|CAA76992.1| 595|Homo sapiens NF2 protein protein. 38 0.049
X72655-1|CAA51220.1| 595|Homo sapiens schwannomin protein. 38 0.049
U72849-1|AAD00186.1| 2033|Homo sapiens envoplakin protein. 38 0.049
>DQ444714-1|ABE01857.1| 805|Homo sapiens cenexin 1 protein.
Length = 805
Score = 70.1 bits (164), Expect = 1e-11
Identities = 47/173 (27%), Positives = 89/173 (51%), Gaps = 13/173 (7%)
Query: 237 ERGGDEKQMALLNQRISQLAENNISLK-SEIER-LKAS----------VIRTEESALANE 284
E GD+ +MA + SQ +SLK E+ER L+A+ + + EE+ ++
Sbjct: 615 EHQGDKLEMAREKHQASQKENKQLSLKVDELERKLEATSAQNIEFLQVIAKREEAIHQSQ 674
Query: 285 KRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQV 344
RL+EK EC L +L+ ++A R +++ E + + Q + +LE QL+ ++ ++
Sbjct: 675 LRLEEKTRECGTLARQLESAIEDARRQVEQTKEHALSKERAAQNKILDLETQLSRTKTEL 734
Query: 345 STAEKEREELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRRT-ASSTGDG 396
S + R++ R +++ L + EQ++ +Q VQ L+ + A+ GDG
Sbjct: 735 SQLRRSRDDADRRYQSRLQDLKDRLEQSESTNRSMQNYVQFLKSSYANVFGDG 787
Score = 62.1 bits (144), Expect = 3e-09
Identities = 67/326 (20%), Positives = 134/326 (41%), Gaps = 10/326 (3%)
Query: 19 QHRETQNKLRE-LEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRT 77
Q + + K+RE + E L T K + + + ++ +A E+ +L+
Sbjct: 451 QQQTLEEKMREDRDSLVERLHRQTAEYSAFKLENERLKASFAPMEDKLNQAHLEVQQLKA 510
Query: 78 LMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQ 137
+K + +Y+ + ++ + +E Q N + +++N EI+ + +FQ +L
Sbjct: 511 SVKNYEGMIDNYKSQVMKTRLEADEVAAQLERCDKENKILKDEMNKEIEAARRQFQSQLA 570
Query: 138 ELAPIPDLLKATQMRLKDAQ-QAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTT 196
+L +PD+LK T+ +L + Q Q Q N + L ++ R ++ H L
Sbjct: 571 DLQQLPDILKITEAKLAECQDQLQGYERKNID-LTAIISDLRSRIEHQGDKLEMAREKHQ 629
Query: 197 MTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLA 256
+ + E+ R K + L+ K E + L ++ +
Sbjct: 630 ASQKENKQLSLKVDELER--KLEATSAQNIEFLQVIAKREE--AIHQSQLRLEEKTRECG 685
Query: 257 ENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAH 316
L+S IE + V +T+E AL+ E+ Q K+ L +L RT+ E S+ +
Sbjct: 686 TLARQLESAIEDARRQVEQTKEHALSKERAAQNKI---LDLETQLSRTKTELSQLRRSRD 742
Query: 317 EQTETVRKCLQTTVAELERQLAASRA 342
+ + LQ LE+ + +R+
Sbjct: 743 DADRRYQSRLQDLKDRLEQSESTNRS 768
Score = 35.9 bits (79), Expect = 0.26
Identities = 77/389 (19%), Positives = 153/389 (39%), Gaps = 25/389 (6%)
Query: 20 HRETQNKLRELEMK--FEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRT 77
+R ++ LRE K E L L+ +A ++ + L Q + +E++EL
Sbjct: 243 NRTLRDLLREQHCKEDSERLMEQQGALLKRLAEADSEKARLLLLLQ---DKDKEVEELLQ 299
Query: 78 LMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQI-NLEIQ--RVKLKFQE 134
++ + Q + + + + Q N+R+ QI NLE + K + +
Sbjct: 300 EIQCEKAQAKTASELSKSMESMRGHLQAQLRSKEAENSRLCMQIKNLERSGNQHKAEVEA 359
Query: 135 KLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLV 194
+++L + + LK A +AQ +E+ A +L H+ LY+
Sbjct: 360 IMEQLKELKQKGDRDKESLKKAIRAQKERAEKSEEYAEQL--------HVQLADKDLYVA 411
Query: 195 TTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHN--SLKPPEKPPERGGDEKQMALLNQRI 252
++ + +Q +G+ + + VL L ++ E E + +L+ +
Sbjct: 412 EALSTLESWRSRYNQVVKEKGDLELEIIVLNDRVTDLVNQQQTLEEKMREDRDSLVERLH 471
Query: 253 SQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRAL 312
Q AE + + K E ERLKAS E+ +Q+ G +D + + +
Sbjct: 472 RQTAEYS-AFKLENERLKASFAPMEDKLNQAHLEVQQLKASVKNYEGMIDNYKSQVMKTR 530
Query: 313 QRAHEQTETVRKCLQTTVA---ELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENF 369
A E + +C + E+ +++ A+R Q + + ++L + L +L E
Sbjct: 531 LEADEVAAQLERCDKENKILKDEMNKEIEAARRQFQSQLADLQQLPDILKITEAKLAECQ 590
Query: 370 EQAQ---LRILGLQTQVQSLRRTASSTGD 395
+Q Q + + L + LR GD
Sbjct: 591 DQLQGYERKNIDLTAIISDLRSRIEHQGD 619
Score = 33.9 bits (74), Expect = 1.1
Identities = 35/146 (23%), Positives = 61/146 (41%), Gaps = 10/146 (6%)
Query: 244 QMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQ------- 296
+M +++I L LKSE++ K + ++ L+E HE A+
Sbjct: 95 KMNRYDKKIDSLMNAVGCLKSEVKMQKGERQMAKRFLEERKEELEEVAHELAETEHENTV 154
Query: 297 LGGELDRTRDEAS-RALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELK 355
L ++R ++E LQ+ H Q E ++CL + + E E AA+ QV + +LK
Sbjct: 155 LRHNIERMKEEKDFTILQKKHLQQE--KECLMSKLVEAEMDGAAAAKQVMALKDTIGKLK 212
Query: 356 NRLHWQMKRLTENFEQAQLRILGLQT 381
+ Q +L + L T
Sbjct: 213 TEKQMTCTDINTLTRQKELLLQKLST 238
>DQ444713-1|ABE01856.1| 824|Homo sapiens cenexin 1 variant 1
protein.
Length = 824
Score = 70.1 bits (164), Expect = 1e-11
Identities = 47/173 (27%), Positives = 89/173 (51%), Gaps = 13/173 (7%)
Query: 237 ERGGDEKQMALLNQRISQLAENNISLK-SEIER-LKAS----------VIRTEESALANE 284
E GD+ +MA + SQ +SLK E+ER L+A+ + + EE+ ++
Sbjct: 634 EHQGDKLEMAREKHQASQKENKQLSLKVDELERKLEATSAQNIEFLQVIAKREEAIHQSQ 693
Query: 285 KRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQV 344
RL+EK EC L +L+ ++A R +++ E + + Q + +LE QL+ ++ ++
Sbjct: 694 LRLEEKTRECGTLARQLESAIEDARRQVEQTKEHALSKERAAQNKILDLETQLSRTKTEL 753
Query: 345 STAEKEREELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRRT-ASSTGDG 396
S + R++ R +++ L + EQ++ +Q VQ L+ + A+ GDG
Sbjct: 754 SQLRRSRDDADRRYQSRLQDLKDRLEQSESTNRSMQNYVQFLKSSYANVFGDG 806
Score = 62.1 bits (144), Expect = 3e-09
Identities = 67/326 (20%), Positives = 134/326 (41%), Gaps = 10/326 (3%)
Query: 19 QHRETQNKLRE-LEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRT 77
Q + + K+RE + E L T K + + + ++ +A E+ +L+
Sbjct: 470 QQQTLEEKMREDRDSLVERLHRQTAEYSAFKLENERLKASFAPMEDKLNQAHLEVQQLKA 529
Query: 78 LMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQ 137
+K + +Y+ + ++ + +E Q N + +++N EI+ + +FQ +L
Sbjct: 530 SVKNYEGMIDNYKSQVMKTRLEADEVAAQLERCDKENKILKDEMNKEIEAARRQFQSQLA 589
Query: 138 ELAPIPDLLKATQMRLKDAQ-QAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTT 196
+L +PD+LK T+ +L + Q Q Q N + L ++ R ++ H L
Sbjct: 590 DLQQLPDILKITEAKLAECQDQLQGYERKNID-LTAIISDLRSRIEHQGDKLEMAREKHQ 648
Query: 197 MTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLA 256
+ + E+ R K + L+ K E + L ++ +
Sbjct: 649 ASQKENKQLSLKVDELER--KLEATSAQNIEFLQVIAKREE--AIHQSQLRLEEKTRECG 704
Query: 257 ENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAH 316
L+S IE + V +T+E AL+ E+ Q K+ L +L RT+ E S+ +
Sbjct: 705 TLARQLESAIEDARRQVEQTKEHALSKERAAQNKI---LDLETQLSRTKTELSQLRRSRD 761
Query: 317 EQTETVRKCLQTTVAELERQLAASRA 342
+ + LQ LE+ + +R+
Sbjct: 762 DADRRYQSRLQDLKDRLEQSESTNRS 787
Score = 35.9 bits (79), Expect = 0.26
Identities = 77/389 (19%), Positives = 153/389 (39%), Gaps = 25/389 (6%)
Query: 20 HRETQNKLRELEMK--FEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRT 77
+R ++ LRE K E L L+ +A ++ + L Q + +E++EL
Sbjct: 262 NRTLRDLLREQHCKEDSERLMEQQGALLKRLAEADSEKARLLLLLQ---DKDKEVEELLQ 318
Query: 78 LMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQI-NLEIQ--RVKLKFQE 134
++ + Q + + + + Q N+R+ QI NLE + K + +
Sbjct: 319 EIQCEKAQAKTASELSKSMESMRGHLQAQLRSKEAENSRLCMQIKNLERSGNQHKAEVEA 378
Query: 135 KLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLV 194
+++L + + LK A +AQ +E+ A +L H+ LY+
Sbjct: 379 IMEQLKELKQKGDRDKESLKKAIRAQKERAEKSEEYAEQL--------HVQLADKDLYVA 430
Query: 195 TTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHN--SLKPPEKPPERGGDEKQMALLNQRI 252
++ + +Q +G+ + + VL L ++ E E + +L+ +
Sbjct: 431 EALSTLESWRSRYNQVVKEKGDLELEIIVLNDRVTDLVNQQQTLEEKMREDRDSLVERLH 490
Query: 253 SQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRAL 312
Q AE + + K E ERLKAS E+ +Q+ G +D + + +
Sbjct: 491 RQTAEYS-AFKLENERLKASFAPMEDKLNQAHLEVQQLKASVKNYEGMIDNYKSQVMKTR 549
Query: 313 QRAHEQTETVRKCLQTTVA---ELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENF 369
A E + +C + E+ +++ A+R Q + + ++L + L +L E
Sbjct: 550 LEADEVAAQLERCDKENKILKDEMNKEIEAARRQFQSQLADLQQLPDILKITEAKLAECQ 609
Query: 370 EQAQ---LRILGLQTQVQSLRRTASSTGD 395
+Q Q + + L + LR GD
Sbjct: 610 DQLQGYERKNIDLTAIISDLRSRIEHQGD 638
Score = 33.9 bits (74), Expect = 1.1
Identities = 35/146 (23%), Positives = 61/146 (41%), Gaps = 10/146 (6%)
Query: 244 QMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQ------- 296
+M +++I L LKSE++ K + ++ L+E HE A+
Sbjct: 114 KMNRYDKKIDSLMNAVGCLKSEVKMQKGERQMAKRFLEERKEELEEVAHELAETEHENTV 173
Query: 297 LGGELDRTRDEAS-RALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELK 355
L ++R ++E LQ+ H Q E ++CL + + E E AA+ QV + +LK
Sbjct: 174 LRHNIERMKEEKDFTILQKKHLQQE--KECLMSKLVEAEMDGAAAAKQVMALKDTIGKLK 231
Query: 356 NRLHWQMKRLTENFEQAQLRILGLQT 381
+ Q +L + L T
Sbjct: 232 TEKQMTCTDINTLTRQKELLLQKLST 257
>BC091500-1|AAH91500.1| 829|Homo sapiens ODF2 protein protein.
Length = 829
Score = 70.1 bits (164), Expect = 1e-11
Identities = 47/173 (27%), Positives = 89/173 (51%), Gaps = 13/173 (7%)
Query: 237 ERGGDEKQMALLNQRISQLAENNISLK-SEIER-LKAS----------VIRTEESALANE 284
E GD+ +MA + SQ +SLK E+ER L+A+ + + EE+ ++
Sbjct: 639 EHQGDKLEMAREKHQASQKENKQLSLKVDELERKLEATSAQNIEFLQVIAKREEAIHQSQ 698
Query: 285 KRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQV 344
RL+EK EC L +L+ ++A R +++ E + + Q + +LE QL+ ++ ++
Sbjct: 699 LRLEEKTRECGTLARQLESAIEDARRQVEQTKEHALSKERAAQNKILDLETQLSRTKTEL 758
Query: 345 STAEKEREELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRRT-ASSTGDG 396
S + R++ R +++ L + EQ++ +Q VQ L+ + A+ GDG
Sbjct: 759 SQLRRSRDDADRRYQSRLQDLKDRLEQSESTNRSMQNYVQFLKSSYANVFGDG 811
Score = 62.1 bits (144), Expect = 3e-09
Identities = 67/326 (20%), Positives = 134/326 (41%), Gaps = 10/326 (3%)
Query: 19 QHRETQNKLRE-LEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRT 77
Q + + K+RE + E L T K + + + ++ +A E+ +L+
Sbjct: 475 QQQTLEEKMREDRDSLVERLHRQTAEYSAFKLENERLKASFAPMEDKLNQAHLEVQQLKA 534
Query: 78 LMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQ 137
+K + +Y+ + ++ + +E Q N + +++N EI+ + +FQ +L
Sbjct: 535 SVKNYEGMIDNYKSQVMKTRLEADEVAAQLERCDKENKILKDEMNKEIEAARRQFQSQLA 594
Query: 138 ELAPIPDLLKATQMRLKDAQ-QAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTT 196
+L +PD+LK T+ +L + Q Q Q N + L ++ R ++ H L
Sbjct: 595 DLQQLPDILKITEAKLAECQDQLQGYERKNID-LTAIISDLRSRIEHQGDKLEMAREKHQ 653
Query: 197 MTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLA 256
+ + E+ R K + L+ K E + L ++ +
Sbjct: 654 ASQKENKQLSLKVDELER--KLEATSAQNIEFLQVIAKREE--AIHQSQLRLEEKTRECG 709
Query: 257 ENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAH 316
L+S IE + V +T+E AL+ E+ Q K+ L +L RT+ E S+ +
Sbjct: 710 TLARQLESAIEDARRQVEQTKEHALSKERAAQNKI---LDLETQLSRTKTELSQLRRSRD 766
Query: 317 EQTETVRKCLQTTVAELERQLAASRA 342
+ + LQ LE+ + +R+
Sbjct: 767 DADRRYQSRLQDLKDRLEQSESTNRS 792
Score = 35.9 bits (79), Expect = 0.26
Identities = 77/389 (19%), Positives = 153/389 (39%), Gaps = 25/389 (6%)
Query: 20 HRETQNKLRELEMK--FEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRT 77
+R ++ LRE K E L L+ +A ++ + L Q + +E++EL
Sbjct: 267 NRTLRDLLREQHCKEDSERLMEQQGALLKRLAEADSEKARLLLLLQ---DKDKEVEELLQ 323
Query: 78 LMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQI-NLEIQ--RVKLKFQE 134
++ + Q + + + + Q N+R+ QI NLE + K + +
Sbjct: 324 EIQCEKAQAKTASELSKSMESMRGHLQAQLRSKEAENSRLCMQIKNLERSGNQHKAEVEA 383
Query: 135 KLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLV 194
+++L + + LK A +AQ +E+ A +L H+ LY+
Sbjct: 384 IMEQLKELKQKGDRDKESLKKAIRAQKERAEKSEEYAEQL--------HVQLADKDLYVA 435
Query: 195 TTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHN--SLKPPEKPPERGGDEKQMALLNQRI 252
++ + +Q +G+ + + VL L ++ E E + +L+ +
Sbjct: 436 EALSTLESWRSRYNQVVKEKGDLELEIIVLNDRVTDLVNQQQTLEEKMREDRDSLVERLH 495
Query: 253 SQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRAL 312
Q AE + + K E ERLKAS E+ +Q+ G +D + + +
Sbjct: 496 RQTAEYS-AFKLENERLKASFAPMEDKLNQAHLEVQQLKASVKNYEGMIDNYKSQVMKTR 554
Query: 313 QRAHEQTETVRKCLQTTVA---ELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENF 369
A E + +C + E+ +++ A+R Q + + ++L + L +L E
Sbjct: 555 LEADEVAAQLERCDKENKILKDEMNKEIEAARRQFQSQLADLQQLPDILKITEAKLAECQ 614
Query: 370 EQAQ---LRILGLQTQVQSLRRTASSTGD 395
+Q Q + + L + LR GD
Sbjct: 615 DQLQGYERKNIDLTAIISDLRSRIEHQGD 643
Score = 33.9 bits (74), Expect = 1.1
Identities = 35/146 (23%), Positives = 61/146 (41%), Gaps = 10/146 (6%)
Query: 244 QMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQ------- 296
+M +++I L LKSE++ K + ++ L+E HE A+
Sbjct: 119 KMNRYDKKIDSLMNAVGCLKSEVKMQKGERQMAKRFLEERKEELEEVAHELAETEHENTV 178
Query: 297 LGGELDRTRDEAS-RALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELK 355
L ++R ++E LQ+ H Q E ++CL + + E E AA+ QV + +LK
Sbjct: 179 LRHNIERMKEEKDFTILQKKHLQQE--KECLMSKLVEAEMDGAAAAKQVMALKDTIGKLK 236
Query: 356 NRLHWQMKRLTENFEQAQLRILGLQT 381
+ Q +L + L T
Sbjct: 237 TEKQMTCTDINTLTRQKELLLQKLST 262
>BC010629-1|AAH10629.1| 763|Homo sapiens outer dense fiber of sperm
tails 2 protein.
Length = 763
Score = 70.1 bits (164), Expect = 1e-11
Identities = 47/173 (27%), Positives = 89/173 (51%), Gaps = 13/173 (7%)
Query: 237 ERGGDEKQMALLNQRISQLAENNISLK-SEIER-LKAS----------VIRTEESALANE 284
E GD+ +MA + SQ +SLK E+ER L+A+ + + EE+ ++
Sbjct: 573 EHQGDKLEMAREKHQASQKENKQLSLKVDELERKLEATSAQNIEFLQVIAKREEAIHQSQ 632
Query: 285 KRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQV 344
RL+EK EC L +L+ ++A R +++ E + + Q + +LE QL+ ++ ++
Sbjct: 633 LRLEEKTRECGTLARQLESAIEDARRQVEQTKEHALSKERAAQNKILDLETQLSRTKTEL 692
Query: 345 STAEKEREELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRRT-ASSTGDG 396
S + R++ R +++ L + EQ++ +Q VQ L+ + A+ GDG
Sbjct: 693 SQLRRSRDDADRRYQSRLQDLKDRLEQSESTNRSMQNYVQFLKSSYANVFGDG 745
Score = 62.1 bits (144), Expect = 3e-09
Identities = 67/326 (20%), Positives = 134/326 (41%), Gaps = 10/326 (3%)
Query: 19 QHRETQNKLRE-LEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRT 77
Q + + K+RE + E L T K + + + ++ +A E+ +L+
Sbjct: 409 QQQTLEEKMREDRDSLVERLHRQTAEYSAFKLENERLKASFAPMEDKLNQAHLEVQQLKA 468
Query: 78 LMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQ 137
+K + +Y+ + ++ + +E Q N + +++N EI+ + +FQ +L
Sbjct: 469 SVKNYEGMIDNYKSQVMKTRLEADEVAAQLERCDKENKILKDEMNKEIEAARRQFQSQLA 528
Query: 138 ELAPIPDLLKATQMRLKDAQ-QAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTT 196
+L +PD+LK T+ +L + Q Q Q N + L ++ R ++ H L
Sbjct: 529 DLQQLPDILKITEAKLAECQDQLQGYERKNID-LTAIISDLRSRIEHQGDKLEMAREKHQ 587
Query: 197 MTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLA 256
+ + E+ R K + L+ K E + L ++ +
Sbjct: 588 ASQKENKQLSLKVDELER--KLEATSAQNIEFLQVIAKREE--AIHQSQLRLEEKTRECG 643
Query: 257 ENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAH 316
L+S IE + V +T+E AL+ E+ Q K+ L +L RT+ E S+ +
Sbjct: 644 TLARQLESAIEDARRQVEQTKEHALSKERAAQNKI---LDLETQLSRTKTELSQLRRSRD 700
Query: 317 EQTETVRKCLQTTVAELERQLAASRA 342
+ + LQ LE+ + +R+
Sbjct: 701 DADRRYQSRLQDLKDRLEQSESTNRS 726
Score = 35.9 bits (79), Expect = 0.26
Identities = 77/389 (19%), Positives = 153/389 (39%), Gaps = 25/389 (6%)
Query: 20 HRETQNKLRELEMK--FEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRT 77
+R ++ LRE K E L L+ +A ++ + L Q + +E++EL
Sbjct: 201 NRTLRDLLREQHCKEDSERLMEQQGALLKRLAEADSEKARLLLLLQ---DKDKEVEELLQ 257
Query: 78 LMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQI-NLEIQ--RVKLKFQE 134
++ + Q + + + + Q N+R+ QI NLE + K + +
Sbjct: 258 EIQCEKAQAKTASELSKSMESMRGHLQAQLRSKEAENSRLCMQIKNLERSGNQHKAEVEA 317
Query: 135 KLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLV 194
+++L + + LK A +AQ +E+ A +L H+ LY+
Sbjct: 318 IMEQLKELKQKGDRDKESLKKAIRAQKERAEKSEEYAEQL--------HVQLADKDLYVA 369
Query: 195 TTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHN--SLKPPEKPPERGGDEKQMALLNQRI 252
++ + +Q +G+ + + VL L ++ E E + +L+ +
Sbjct: 370 EALSTLESWRSRYNQVVKEKGDLELEIIVLNDRVTDLVNQQQTLEEKMREDRDSLVERLH 429
Query: 253 SQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRAL 312
Q AE + + K E ERLKAS E+ +Q+ G +D + + +
Sbjct: 430 RQTAEYS-AFKLENERLKASFAPMEDKLNQAHLEVQQLKASVKNYEGMIDNYKSQVMKTR 488
Query: 313 QRAHEQTETVRKCLQTTVA---ELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENF 369
A E + +C + E+ +++ A+R Q + + ++L + L +L E
Sbjct: 489 LEADEVAAQLERCDKENKILKDEMNKEIEAARRQFQSQLADLQQLPDILKITEAKLAECQ 548
Query: 370 EQAQ---LRILGLQTQVQSLRRTASSTGD 395
+Q Q + + L + LR GD
Sbjct: 549 DQLQGYERKNIDLTAIISDLRSRIEHQGD 577
Score = 33.9 bits (74), Expect = 1.1
Identities = 35/146 (23%), Positives = 61/146 (41%), Gaps = 10/146 (6%)
Query: 244 QMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQ------- 296
+M +++I L LKSE++ K + ++ L+E HE A+
Sbjct: 53 KMNRYDKKIDSLMNAVGCLKSEVKMQKGERQMAKRFLEERKEELEEVAHELAETEHENTV 112
Query: 297 LGGELDRTRDEAS-RALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELK 355
L ++R ++E LQ+ H Q E ++CL + + E E AA+ QV + +LK
Sbjct: 113 LRHNIERMKEEKDFTILQKKHLQQE--KECLMSKLVEAEMDGAAAAKQVMALKDTIGKLK 170
Query: 356 NRLHWQMKRLTENFEQAQLRILGLQT 381
+ Q +L + L T
Sbjct: 171 TEKQMTCTDINTLTRQKELLLQKLST 196
>AY366499-1|AAQ73195.1| 805|Homo sapiens outer dense fiber of sperm
tails 2 protein.
Length = 805
Score = 70.1 bits (164), Expect = 1e-11
Identities = 47/173 (27%), Positives = 89/173 (51%), Gaps = 13/173 (7%)
Query: 237 ERGGDEKQMALLNQRISQLAENNISLK-SEIER-LKAS----------VIRTEESALANE 284
E GD+ +MA + SQ +SLK E+ER L+A+ + + EE+ ++
Sbjct: 615 EHQGDKLEMAREKHQASQKENKQLSLKVDELERKLEATSAQNIEFLQVIAKREEAIHQSQ 674
Query: 285 KRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQV 344
RL+EK EC L +L+ ++A R +++ E + + Q + +LE QL+ ++ ++
Sbjct: 675 LRLEEKTRECGTLARQLESAIEDARRQVEQTKEHALSKERAAQNKILDLETQLSRTKTEL 734
Query: 345 STAEKEREELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRRT-ASSTGDG 396
S + R++ R +++ L + EQ++ +Q VQ L+ + A+ GDG
Sbjct: 735 SQLRRSRDDADRRYQSRLQDLKDRLEQSESTNRSMQNYVQFLKSSYANVFGDG 787
Score = 62.1 bits (144), Expect = 3e-09
Identities = 67/326 (20%), Positives = 134/326 (41%), Gaps = 10/326 (3%)
Query: 19 QHRETQNKLRE-LEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRT 77
Q + + K+RE + E L T K + + + ++ +A E+ +L+
Sbjct: 451 QQQTLEEKMREDRDSLVERLHRQTAEYSAFKLENERLKASFAPMEDKLNQAHLEVQQLKA 510
Query: 78 LMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQ 137
+K + +Y+ + ++ + +E Q N + +++N EI+ + +FQ +L
Sbjct: 511 SVKNYEGMIDNYKSQVMKTRLEADEVAAQLERCDKENKILKDEMNKEIEAARRQFQSQLA 570
Query: 138 ELAPIPDLLKATQMRLKDAQ-QAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTT 196
+L +PD+LK T+ +L + Q Q Q N + L ++ R ++ H L
Sbjct: 571 DLQQLPDILKITEAKLAECQDQLQGYERKNID-LTAIISDLRSRIEHQGDKLEMAREKHQ 629
Query: 197 MTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLA 256
+ + E+ R K + L+ K E + L ++ +
Sbjct: 630 ASQKENKQLSLKVDELER--KLEATSAQNIEFLQVIAKREE--AIHQSQLRLEEKTRECG 685
Query: 257 ENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAH 316
L+S IE + V +T+E AL+ E+ Q K+ L +L RT+ E S+ +
Sbjct: 686 TLARQLESAIEDARRQVEQTKEHALSKERAAQNKI---LDLETQLSRTKTELSQLRRSRD 742
Query: 317 EQTETVRKCLQTTVAELERQLAASRA 342
+ + LQ LE+ + +R+
Sbjct: 743 DADRRYQSRLQDLKDRLEQSESTNRS 768
Score = 35.9 bits (79), Expect = 0.26
Identities = 77/389 (19%), Positives = 153/389 (39%), Gaps = 25/389 (6%)
Query: 20 HRETQNKLRELEMK--FEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRT 77
+R ++ LRE K E L L+ +A ++ + L Q + +E++EL
Sbjct: 243 NRTLRDLLREQHCKEDSERLMEQQGALLKRLAEADSEKARLLLLLQ---DKDKEVEELLQ 299
Query: 78 LMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQI-NLEIQ--RVKLKFQE 134
++ + Q + + + + Q N+R+ QI NLE + K + +
Sbjct: 300 EIQCEKAQAKTASELSKSMESMRGHLQAQLRSKEAENSRLCMQIKNLERSGNQHKAEVEA 359
Query: 135 KLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLV 194
+++L + + LK A +AQ +E+ A +L H+ LY+
Sbjct: 360 IMEQLKELKQKGDRDKESLKKAIRAQKERAEKSEEYAEQL--------HVQLADKDLYVA 411
Query: 195 TTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHN--SLKPPEKPPERGGDEKQMALLNQRI 252
++ + +Q +G+ + + VL L ++ E E + +L+ +
Sbjct: 412 EALSTLESWRSRYNQVVKEKGDLELEIIVLNDRVTDLVNQQQTLEEKMREDRDSLVERLH 471
Query: 253 SQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRAL 312
Q AE + + K E ERLKAS E+ +Q+ G +D + + +
Sbjct: 472 RQTAEYS-AFKLENERLKASFAPMEDKLNQAHLEVQQLKASVKNYEGMIDNYKSQVMKTR 530
Query: 313 QRAHEQTETVRKCLQTTVA---ELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENF 369
A E + +C + E+ +++ A+R Q + + ++L + L +L E
Sbjct: 531 LEADEVAAQLERCDKENKILKDEMNKEIEAARRQFQSQLADLQQLPDILKITEAKLAECQ 590
Query: 370 EQAQ---LRILGLQTQVQSLRRTASSTGD 395
+Q Q + + L + LR GD
Sbjct: 591 DQLQGYERKNIDLTAIISDLRSRIEHQGD 619
Score = 33.9 bits (74), Expect = 1.1
Identities = 35/146 (23%), Positives = 61/146 (41%), Gaps = 10/146 (6%)
Query: 244 QMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQ------- 296
+M +++I L LKSE++ K + ++ L+E HE A+
Sbjct: 95 KMNRYDKKIDSLMNAVGCLKSEVKMQKGERQMAKRFLEERKEELEEVAHELAETEHENTV 154
Query: 297 LGGELDRTRDEAS-RALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELK 355
L ++R ++E LQ+ H Q E ++CL + + E E AA+ QV + +LK
Sbjct: 155 LRHNIERMKEEKDFTILQKKHLQQE--KECLMSKLVEAEMDGAAAAKQVMALKDTIGKLK 212
Query: 356 NRLHWQMKRLTENFEQAQLRILGLQT 381
+ Q +L + L T
Sbjct: 213 TEKQMTCTDINTLTRQKELLLQKLST 238
>AL445287-6|CAH71069.1| 805|Homo sapiens outer dense fiber of sperm
tails 2 protein.
Length = 805
Score = 70.1 bits (164), Expect = 1e-11
Identities = 47/173 (27%), Positives = 89/173 (51%), Gaps = 13/173 (7%)
Query: 237 ERGGDEKQMALLNQRISQLAENNISLK-SEIER-LKAS----------VIRTEESALANE 284
E GD+ +MA + SQ +SLK E+ER L+A+ + + EE+ ++
Sbjct: 615 EHQGDKLEMAREKHQASQKENKQLSLKVDELERKLEATSAQNIEFLQVIAKREEAIHQSQ 674
Query: 285 KRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQV 344
RL+EK EC L +L+ ++A R +++ E + + Q + +LE QL+ ++ ++
Sbjct: 675 LRLEEKTRECGTLARQLESAIEDARRQVEQTKEHALSKERAAQNKILDLETQLSRTKTEL 734
Query: 345 STAEKEREELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRRT-ASSTGDG 396
S + R++ R +++ L + EQ++ +Q VQ L+ + A+ GDG
Sbjct: 735 SQLRRSRDDADRRYQSRLQDLKDRLEQSESTNRSMQNYVQFLKSSYANVFGDG 787
Score = 62.1 bits (144), Expect = 3e-09
Identities = 67/326 (20%), Positives = 134/326 (41%), Gaps = 10/326 (3%)
Query: 19 QHRETQNKLRE-LEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRT 77
Q + + K+RE + E L T K + + + ++ +A E+ +L+
Sbjct: 451 QQQTLEEKMREDRDSLVERLHRQTAEYSAFKLENERLKASFAPMEDKLNQAHLEVQQLKA 510
Query: 78 LMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQ 137
+K + +Y+ + ++ + +E Q N + +++N EI+ + +FQ +L
Sbjct: 511 SVKNYEGMIDNYKSQVMKTRLEADEVAAQLERCDKENKILKDEMNKEIEAARRQFQSQLA 570
Query: 138 ELAPIPDLLKATQMRLKDAQ-QAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTT 196
+L +PD+LK T+ +L + Q Q Q N + L ++ R ++ H L
Sbjct: 571 DLQQLPDILKITEAKLAECQDQLQGYERKNID-LTAIISDLRSRIEHQGDKLEMAREKHQ 629
Query: 197 MTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLA 256
+ + E+ R K + L+ K E + L ++ +
Sbjct: 630 ASQKENKQLSLKVDELER--KLEATSAQNIEFLQVIAKREE--AIHQSQLRLEEKTRECG 685
Query: 257 ENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAH 316
L+S IE + V +T+E AL+ E+ Q K+ L +L RT+ E S+ +
Sbjct: 686 TLARQLESAIEDARRQVEQTKEHALSKERAAQNKI---LDLETQLSRTKTELSQLRRSRD 742
Query: 317 EQTETVRKCLQTTVAELERQLAASRA 342
+ + LQ LE+ + +R+
Sbjct: 743 DADRRYQSRLQDLKDRLEQSESTNRS 768
Score = 35.9 bits (79), Expect = 0.26
Identities = 77/389 (19%), Positives = 153/389 (39%), Gaps = 25/389 (6%)
Query: 20 HRETQNKLRELEMK--FEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRT 77
+R ++ LRE K E L L+ +A ++ + L Q + +E++EL
Sbjct: 243 NRTLRDLLREQHCKEDSERLMEQQGALLKRLAEADSEKARLLLLLQ---DKDKEVEELLQ 299
Query: 78 LMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQI-NLEIQ--RVKLKFQE 134
++ + Q + + + + Q N+R+ QI NLE + K + +
Sbjct: 300 EIQCEKAQAKTASELSKSMESMRGHLQAQLRSKEAENSRLCMQIKNLERSGNQHKAEVEA 359
Query: 135 KLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLV 194
+++L + + LK A +AQ +E+ A +L H+ LY+
Sbjct: 360 IMEQLKELKQKGDRDKESLKKAIRAQKERAEKSEEYAEQL--------HVQLADKDLYVA 411
Query: 195 TTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHN--SLKPPEKPPERGGDEKQMALLNQRI 252
++ + +Q +G+ + + VL L ++ E E + +L+ +
Sbjct: 412 EALSTLESWRSRYNQVVKEKGDLELEIIVLNDRVTDLVNQQQTLEEKMREDRDSLVERLH 471
Query: 253 SQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRAL 312
Q AE + + K E ERLKAS E+ +Q+ G +D + + +
Sbjct: 472 RQTAEYS-AFKLENERLKASFAPMEDKLNQAHLEVQQLKASVKNYEGMIDNYKSQVMKTR 530
Query: 313 QRAHEQTETVRKCLQTTVA---ELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENF 369
A E + +C + E+ +++ A+R Q + + ++L + L +L E
Sbjct: 531 LEADEVAAQLERCDKENKILKDEMNKEIEAARRQFQSQLADLQQLPDILKITEAKLAECQ 590
Query: 370 EQAQ---LRILGLQTQVQSLRRTASSTGD 395
+Q Q + + L + LR GD
Sbjct: 591 DQLQGYERKNIDLTAIISDLRSRIEHQGD 619
Score = 33.9 bits (74), Expect = 1.1
Identities = 35/146 (23%), Positives = 61/146 (41%), Gaps = 10/146 (6%)
Query: 244 QMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQ------- 296
+M +++I L LKSE++ K + ++ L+E HE A+
Sbjct: 95 KMNRYDKKIDSLMNAVGCLKSEVKMQKGERQMAKRFLEERKEELEEVAHELAETEHENTV 154
Query: 297 LGGELDRTRDEAS-RALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELK 355
L ++R ++E LQ+ H Q E ++CL + + E E AA+ QV + +LK
Sbjct: 155 LRHNIERMKEEKDFTILQKKHLQQE--KECLMSKLVEAEMDGAAAAKQVMALKDTIGKLK 212
Query: 356 NRLHWQMKRLTENFEQAQLRILGLQT 381
+ Q +L + L T
Sbjct: 213 TEKQMTCTDINTLTRQKELLLQKLST 238
>AL359091-23|CAI13506.1| 805|Homo sapiens outer dense fiber of
sperm tails 2 protein.
Length = 805
Score = 70.1 bits (164), Expect = 1e-11
Identities = 47/173 (27%), Positives = 89/173 (51%), Gaps = 13/173 (7%)
Query: 237 ERGGDEKQMALLNQRISQLAENNISLK-SEIER-LKAS----------VIRTEESALANE 284
E GD+ +MA + SQ +SLK E+ER L+A+ + + EE+ ++
Sbjct: 615 EHQGDKLEMAREKHQASQKENKQLSLKVDELERKLEATSAQNIEFLQVIAKREEAIHQSQ 674
Query: 285 KRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQV 344
RL+EK EC L +L+ ++A R +++ E + + Q + +LE QL+ ++ ++
Sbjct: 675 LRLEEKTRECGTLARQLESAIEDARRQVEQTKEHALSKERAAQNKILDLETQLSRTKTEL 734
Query: 345 STAEKEREELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRRT-ASSTGDG 396
S + R++ R +++ L + EQ++ +Q VQ L+ + A+ GDG
Sbjct: 735 SQLRRSRDDADRRYQSRLQDLKDRLEQSESTNRSMQNYVQFLKSSYANVFGDG 787
Score = 62.1 bits (144), Expect = 3e-09
Identities = 67/326 (20%), Positives = 134/326 (41%), Gaps = 10/326 (3%)
Query: 19 QHRETQNKLRE-LEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRT 77
Q + + K+RE + E L T K + + + ++ +A E+ +L+
Sbjct: 451 QQQTLEEKMREDRDSLVERLHRQTAEYSAFKLENERLKASFAPMEDKLNQAHLEVQQLKA 510
Query: 78 LMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQ 137
+K + +Y+ + ++ + +E Q N + +++N EI+ + +FQ +L
Sbjct: 511 SVKNYEGMIDNYKSQVMKTRLEADEVAAQLERCDKENKILKDEMNKEIEAARRQFQSQLA 570
Query: 138 ELAPIPDLLKATQMRLKDAQ-QAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTT 196
+L +PD+LK T+ +L + Q Q Q N + L ++ R ++ H L
Sbjct: 571 DLQQLPDILKITEAKLAECQDQLQGYERKNID-LTAIISDLRSRIEHQGDKLEMAREKHQ 629
Query: 197 MTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLA 256
+ + E+ R K + L+ K E + L ++ +
Sbjct: 630 ASQKENKQLSLKVDELER--KLEATSAQNIEFLQVIAKREE--AIHQSQLRLEEKTRECG 685
Query: 257 ENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAH 316
L+S IE + V +T+E AL+ E+ Q K+ L +L RT+ E S+ +
Sbjct: 686 TLARQLESAIEDARRQVEQTKEHALSKERAAQNKI---LDLETQLSRTKTELSQLRRSRD 742
Query: 317 EQTETVRKCLQTTVAELERQLAASRA 342
+ + LQ LE+ + +R+
Sbjct: 743 DADRRYQSRLQDLKDRLEQSESTNRS 768
Score = 35.9 bits (79), Expect = 0.26
Identities = 77/389 (19%), Positives = 153/389 (39%), Gaps = 25/389 (6%)
Query: 20 HRETQNKLRELEMK--FEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRT 77
+R ++ LRE K E L L+ +A ++ + L Q + +E++EL
Sbjct: 243 NRTLRDLLREQHCKEDSERLMEQQGALLKRLAEADSEKARLLLLLQ---DKDKEVEELLQ 299
Query: 78 LMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQI-NLEIQ--RVKLKFQE 134
++ + Q + + + + Q N+R+ QI NLE + K + +
Sbjct: 300 EIQCEKAQAKTASELSKSMESMRGHLQAQLRSKEAENSRLCMQIKNLERSGNQHKAEVEA 359
Query: 135 KLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLV 194
+++L + + LK A +AQ +E+ A +L H+ LY+
Sbjct: 360 IMEQLKELKQKGDRDKESLKKAIRAQKERAEKSEEYAEQL--------HVQLADKDLYVA 411
Query: 195 TTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHN--SLKPPEKPPERGGDEKQMALLNQRI 252
++ + +Q +G+ + + VL L ++ E E + +L+ +
Sbjct: 412 EALSTLESWRSRYNQVVKEKGDLELEIIVLNDRVTDLVNQQQTLEEKMREDRDSLVERLH 471
Query: 253 SQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRAL 312
Q AE + + K E ERLKAS E+ +Q+ G +D + + +
Sbjct: 472 RQTAEYS-AFKLENERLKASFAPMEDKLNQAHLEVQQLKASVKNYEGMIDNYKSQVMKTR 530
Query: 313 QRAHEQTETVRKCLQTTVA---ELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENF 369
A E + +C + E+ +++ A+R Q + + ++L + L +L E
Sbjct: 531 LEADEVAAQLERCDKENKILKDEMNKEIEAARRQFQSQLADLQQLPDILKITEAKLAECQ 590
Query: 370 EQAQ---LRILGLQTQVQSLRRTASSTGD 395
+Q Q + + L + LR GD
Sbjct: 591 DQLQGYERKNIDLTAIISDLRSRIEHQGD 619
Score = 33.9 bits (74), Expect = 1.1
Identities = 35/146 (23%), Positives = 61/146 (41%), Gaps = 10/146 (6%)
Query: 244 QMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQ------- 296
+M +++I L LKSE++ K + ++ L+E HE A+
Sbjct: 95 KMNRYDKKIDSLMNAVGCLKSEVKMQKGERQMAKRFLEERKEELEEVAHELAETEHENTV 154
Query: 297 LGGELDRTRDEAS-RALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELK 355
L ++R ++E LQ+ H Q E ++CL + + E E AA+ QV + +LK
Sbjct: 155 LRHNIERMKEEKDFTILQKKHLQQE--KECLMSKLVEAEMDGAAAAKQVMALKDTIGKLK 212
Query: 356 NRLHWQMKRLTENFEQAQLRILGLQT 381
+ Q +L + L T
Sbjct: 213 TEKQMTCTDINTLTRQKELLLQKLST 238
>Z11584-1|CAA77670.1| 2101|Homo sapiens NuMA protein protein.
Length = 2101
Score = 64.9 bits (151), Expect = 5e-10
Identities = 44/180 (24%), Positives = 80/180 (44%)
Query: 207 QSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEI 266
+ ++EI +G Q L PP++ E GD Q+ L Q + LA NN L++ +
Sbjct: 377 EEKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQEAATLAANNTQLQARV 436
Query: 267 ERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCL 326
E L+ + E LA +E+ + + L +L + S+A + + ++ L
Sbjct: 437 EMLETERGQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQAKEELEQASQAHGARL 496
Query: 327 QTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSL 386
VA L +L A + ++E LK + + +L + +Q + GL+ QV+ L
Sbjct: 497 TAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQQQEQASQGLRHQVEQL 556
Score = 42.7 bits (96), Expect = 0.002
Identities = 83/393 (21%), Positives = 158/393 (40%), Gaps = 27/393 (6%)
Query: 24 QNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQN 83
QNKL EL LA + + +A + ++ L++ +E+ L TL+++
Sbjct: 871 QNKLAELHAN---LARALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVARLETLVRKAG 927
Query: 84 DQLQDY---------RVKYLQAQQLVEEQRRQ---XXXXXXXNTRISEQINLEIQRVKLK 131
+Q + R Q + L E+Q RQ R +EQ+ E++R++
Sbjct: 928 EQQETASRELVKEPARAGDRQPEWLEEQQGRQFCSTQAALQAMEREAEQMGNELERLRAA 987
Query: 132 FQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLAR-ELNCAREKVVHIFRYLYS 190
E + + RL ++ +A A+ E+ AR EL + ++ R ++
Sbjct: 988 LMESQGQQQEERGQQEREVARLTQ-ERGRAQADLALEKAARAELEMRLQNALNEQRVEFA 1046
Query: 191 -LYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLN 249
L LT+++ Q +++ RG + + L + + EK+ A +
Sbjct: 1047 TLQEALAHALTEKEGKDQELAKL-RGLEAAQIKELEELRQTVKQLKEQLAKKEKEHASGS 1105
Query: 250 QRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEAS 309
S+ A ++E L+A V + E+ +++ + + + RD A
Sbjct: 1106 GAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQKQQEQA-DSLERSLEAERASRAERDSAL 1164
Query: 310 RALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENF 369
LQ E+ Q+ +A +R+LAA R +V K +E K Q+ R +
Sbjct: 1165 ETLQGQLEEKAQELGHSQSALASAQRELAAFRTKVQDHSKAEDEWKA----QVARGRQEA 1220
Query: 370 EQAQLRILGLQTQVQSLRRTASSTGDGDGENQE 402
E+ I L+ +V L R + +GE++E
Sbjct: 1221 ERKNSLISSLEEEVSILNRQVL---EKEGESKE 1250
Score = 36.3 bits (80), Expect = 0.20
Identities = 30/148 (20%), Positives = 67/148 (45%), Gaps = 5/148 (3%)
Query: 246 ALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTR 305
A L +++ L +L + I++ + ++ A + +L + + + Q L
Sbjct: 494 ARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQQQEQASQGLRHQV 553
Query: 306 DEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRL 365
++ S +L++ +Q + V + + T + +QLA + + + +ER+ +L
Sbjct: 554 EQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALKQL-----EA 608
Query: 366 TENFEQAQLRILGLQTQVQSLRRTASST 393
E + A+L IL Q QV + R ++ T
Sbjct: 609 LEKEKAAKLEILQQQLQVANEARDSAQT 636
Score = 36.3 bits (80), Expect = 0.20
Identities = 70/347 (20%), Positives = 144/347 (41%), Gaps = 36/347 (10%)
Query: 71 EIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKL 130
++ L + + N +Q + +Q +E++ Q + S+ + +++++
Sbjct: 499 QVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQQQEQASQGLRHQVEQLSS 558
Query: 131 KFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCA--------REKVV 182
++K Q+L + + +AT R AQQ AE L RE + A +EK
Sbjct: 559 SLKQKEQQLKEVAEKQEAT--RQDHAQQLATAAEEREASL-RERDAALKQLEALEKEKAA 615
Query: 183 HIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGR-GNKDQTVHVLLHNSLKPPEKPPERGGD 241
+ L + + + Q+Q E K + + + + + + + +
Sbjct: 616 KLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQVAE 675
Query: 242 -EKQMALLNQRISQ---LAENNISLKSEIERLKASVIRTEESALANEKR-----LQEKMH 292
E Q+ Q+ ++ +A+ L+ +++ LK S ++ + +L EKR L+E+
Sbjct: 676 LELQLRSEQQKATEKERVAQEKDQLQEQLQALKES-LKVTKGSLEEEKRRAADALEEQQR 734
Query: 293 ECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAEL-----------ERQLAASR 341
++L E R+ E + ++ E+ RK L+ + +L R+LA +
Sbjct: 735 CISELKAET-RSLVEQHKRERKELEEERAGRKGLEARLLQLGEAHQAETEVLRRELAEAM 793
Query: 342 AQVSTAEKEREEL-KNRLHWQMKRLTENFEQAQLRILGLQTQVQSLR 387
A TAE E E+L K W+ E+AQ + Q Q+ +L+
Sbjct: 794 AAQHTAESECEQLVKEVAAWRDGYEDSQQEEAQYGAM-FQEQLMTLK 839
Score = 33.5 bits (73), Expect = 1.4
Identities = 40/167 (23%), Positives = 80/167 (47%), Gaps = 18/167 (10%)
Query: 229 LKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQ 288
L+P E R +E L++ + Q + KS+++R K + + E L+ +L+
Sbjct: 273 LEPKELEELRDKNESLTMRLHETLKQCQDLKTE-KSQMDR-KINQLSEENGDLSF--KLR 328
Query: 289 EKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAE 348
E QL L+ +E S+A Q E+ A+LE++L+A+ E
Sbjct: 329 EFASHLQQLQDALNELTEEHSKATQEWLEKQ-----------AQLEKELSAALQDKKCLE 377
Query: 349 KEREELK---NRLHWQMKRLTENFEQAQLRILGLQTQVQSLRRTASS 392
++ E L+ ++L + +L +N Q + +LG Q+++L++ A++
Sbjct: 378 EKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQEAAT 424
Score = 32.7 bits (71), Expect = 2.4
Identities = 36/162 (22%), Positives = 68/162 (41%), Gaps = 8/162 (4%)
Query: 248 LNQRISQLAENNISLKSEIERL--KASVIRTEESALANEKR-LQEKMHECAQ-LGGELDR 303
L Q++++ L++E + S+++ LA E R L E+ + Q L ELD+
Sbjct: 1412 LRQKVAEQERTAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLEVELDQ 1471
Query: 304 TRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMK 363
R++ + L ET +Q R+L A+ A+ + E + R + +
Sbjct: 1472 AREKYVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKVKVLEERQRFQEERQ 1531
Query: 364 RLTENFEQAQLRIL----GLQTQVQSLRRTASSTGDGDGENQ 401
+LT E+ ++ + Q Q L+ + G+ E Q
Sbjct: 1532 KLTAQVEELSKKLADSDQASKVQQQKLKAVQAQGGESQQEAQ 1573
>Z11583-1|CAA77669.1| 2115|Homo sapiens NuMA protein protein.
Length = 2115
Score = 64.9 bits (151), Expect = 5e-10
Identities = 44/180 (24%), Positives = 80/180 (44%)
Query: 207 QSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEI 266
+ ++EI +G Q L PP++ E GD Q+ L Q + LA NN L++ +
Sbjct: 377 EEKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQEAATLAANNTQLQARV 436
Query: 267 ERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCL 326
E L+ + E LA +E+ + + L +L + S+A + + ++ L
Sbjct: 437 EMLETERGQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQAKEELEQASQAHGARL 496
Query: 327 QTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSL 386
VA L +L A + ++E LK + + +L + +Q + GL+ QV+ L
Sbjct: 497 TAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQQQEQASQGLRHQVEQL 556
Score = 42.3 bits (95), Expect = 0.003
Identities = 79/379 (20%), Positives = 157/379 (41%), Gaps = 17/379 (4%)
Query: 26 KLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQ 85
+++E E++ + LA + L K A +EV L+ R+A E+ + + ++ +
Sbjct: 887 QVQEKEVRAQKLADDLSTLQ-EKMAATSKEV--ARLETLVRKAGEQQETASRELVKEPAR 943
Query: 86 LQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDL 145
D + ++L+ QQ Q R +EQ+ E++R++ E +
Sbjct: 944 AGDRQPEWLEEQQ--GRQFCSTQAALQAMEREAEQMGNELERLRAALMESQGQQQEERGQ 1001
Query: 146 LKATQMRLKDAQQAQAIAEHNAEQLAR-ELNCAREKVVHIFRYLYS-LYLVTTMTLTQED 203
+ RL ++ +A A+ E+ AR EL + ++ R ++ L LT+++
Sbjct: 1002 QEREVARLTQ-ERGRAQADLALEKAARAELEMRLQNALNEQRVEFATLQEALAHALTEKE 1060
Query: 204 LFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLK 263
Q +++ RG + + L + + EK+ A + S+ A
Sbjct: 1061 GKDQELAKL-RGLEAAQIKELEELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTG 1119
Query: 264 SEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVR 323
++E L+A V + E+ +++ + + + RD A LQ E+
Sbjct: 1120 PKLEALRAEVSKLEQQCQKQQEQA-DSLERSLEAERASRAERDSALETLQGQLEEKAQEL 1178
Query: 324 KCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQLRILGLQTQV 383
Q+ +A +R+LAA R +V K +E K Q+ R + E+ I L+ +V
Sbjct: 1179 GHSQSALASAQRELAAFRTKVQDHSKAEDEWKA----QVARGRQEAERKNSLISSLEEEV 1234
Query: 384 QSLRRTASSTGDGDGENQE 402
L R + +GE++E
Sbjct: 1235 SILNRQVL---EKEGESKE 1250
Score = 40.3 bits (90), Expect = 0.012
Identities = 77/342 (22%), Positives = 140/342 (40%), Gaps = 25/342 (7%)
Query: 53 EQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXX 112
+Q+ + LKQ +E + ++ + +EQ Q ++V+ L + +EQ+ +
Sbjct: 516 QQDQELAGLKQQAKEKQAQLAQTLQ-QQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQ 574
Query: 113 XNTRI--SEQINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQL 170
TR ++Q+ + + +E+ L + L K +L+ QQ +A +
Sbjct: 575 EATRQDHAQQLATAAEEREASLRERDAALKQLEALEKEKAAKLEILQQQLQVANEARDSA 634
Query: 171 ARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLK 230
+ A+ + + R + L T QE ++Q+++ L K
Sbjct: 635 QTSVTQAQREKAELSRKVEELQACVE-TARQEQ--HEAQAQVAELELQ-----LRSEQQK 686
Query: 231 PPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKR-LQE 289
EK ER EK L +++ L E+ K +E K R AL ++R + E
Sbjct: 687 ATEK--ERVAQEKDQ--LQEQLQALKESLKVTKGSLEEEK----RRAADALEEQQRCISE 738
Query: 290 KMHECAQLGGELDRTRDEAS--RALQRAHE-QTETVRKCLQTTVAELERQLAASRAQVST 346
E L + R R E RA ++ E + + + + Q L R+LA + A T
Sbjct: 739 LKAETRSLVEQHKRERKELEEERAGRKGLEARLQQLGEAHQAETEVLRRELAEAMAAQHT 798
Query: 347 AEKEREEL-KNRLHWQMKRLTENFEQAQLRILGLQTQVQSLR 387
AE E E+L K W+ + E+AQ + Q Q+ +L+
Sbjct: 799 AESECEQLVKEVAAWRERYEDSQQEEAQYGAM-FQEQLMTLK 839
Score = 40.3 bits (90), Expect = 0.012
Identities = 70/330 (21%), Positives = 136/330 (41%), Gaps = 37/330 (11%)
Query: 53 EQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXX 112
E + R+L + ++ R+E++E R K +LQ + +++ + +
Sbjct: 738 ELKAETRSLVEQHKRERKELEEERAGRKGLEARLQQLGEAHQAETEVLRRELAEAMAAQH 797
Query: 113 XNTRISEQINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLK--------DAQQAQ---- 160
EQ+ E+ + ++++ QE A + + M LK + Q+A+
Sbjct: 798 TAESECEQLVKEVAAWRERYEDSQQEEAQYGAMFQEQLMTLKEECEKARQELQEAKEKVA 857
Query: 161 AIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKD-Q 219
I H+ Q++R+ N E ++ R L + D Q ++ +K+
Sbjct: 858 GIESHSELQISRQQNELAELHANLARALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVA 917
Query: 220 TVHVLLHNSLKPPE-------KPPERGGDEKQMALLNQRISQLAENNISLK--------- 263
+ L+ + + E K P R GD + L Q+ Q +L+
Sbjct: 918 RLETLVRKAGEQQETASRELVKEPARAGDRQPEWLEEQQGRQFCSTQAALQAMEREAEQM 977
Query: 264 -SEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETV 322
+E+ERL+A+++ E E+R Q++ E A+L E R R +A AL++A +
Sbjct: 978 GNELERLRAALM--ESQGQQQEERGQQE-REVARLTQE--RGRAQADLALEKAARAELEM 1032
Query: 323 RKCLQTTVAELERQLAASRAQVSTAEKERE 352
R LQ + E + A + ++ A E+E
Sbjct: 1033 R--LQNALNEQRVEFATLQEALAHALTEKE 1060
Score = 38.7 bits (86), Expect = 0.037
Identities = 75/347 (21%), Positives = 147/347 (42%), Gaps = 27/347 (7%)
Query: 60 ALKQCYREARE---EIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTR 116
AL+ REA + E++ LR + E Q Q+ R + + + ++R +
Sbjct: 966 ALQAMEREAEQMGNELERLRAALMESQGQQQEERGQQEREVARLTQERGRAQADLALEKA 1025
Query: 117 ISEQINLEIQRVKLKFQEKLQELAPIPDLLK--ATQMRLKDAQQAQAIAEHNAEQLAREL 174
++ + +Q E+ E A + + L T+ KD + A+ + A Q+ +EL
Sbjct: 1026 ARAELEMRLQNA---LNEQRVEFATLQEALAHALTEKEGKDQELAK-LRGLEAAQI-KEL 1080
Query: 175 NCAREKVVHIFRYLYSLYLV-TTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPE 233
R+ V + L + + Q + G+++ G K + + + + +
Sbjct: 1081 EELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPT---GPKLEALRAEVSKLEQQCQ 1137
Query: 234 KPPERGGDEKQMALLNQRISQLAENNI--SLKSEIERLKASVIRTEESALANEKRLQEKM 291
K E+ D + +L +R S+ ++ +L+ ++E KA + +SALA+ +R
Sbjct: 1138 KQQEQA-DSLERSLEAERASRAERDSALETLQGQLEE-KAQELGHSQSALASAQRELAAF 1195
Query: 292 HECAQLGGEL-DRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQ------V 344
Q + D + + +R Q A E+ ++ L+ V+ L RQ+ + +
Sbjct: 1196 RTKVQDHSKAEDEWKAQVARGRQEA-ERKNSLISSLEEEVSILNRQVLEKEGESKELKRL 1254
Query: 345 STAEKER-EELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRRTA 390
AE E+ ++L+ RL N +A R L+ +VQSLR A
Sbjct: 1255 VMAESEKSQKLEERLRLLQAETASNSARAAERSSALREEVQSLREEA 1301
Score = 38.7 bits (86), Expect = 0.037
Identities = 64/327 (19%), Positives = 127/327 (38%), Gaps = 12/327 (3%)
Query: 24 QNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQN 83
QN L E ++F L + KE ++ +R L+ +E++ELR +K+
Sbjct: 1035 QNALNEQRVEFATLQEALAHALTEKEGKDQELAKLRGLEAA---QIKELEELRQTVKQLK 1091
Query: 84 DQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIP 143
+QL ++ Q ++ E + E+ +++ + Q++ ++ +
Sbjct: 1092 EQLAKKEKEHASGS---GAQSEAAGRTEPTGPKL-EALRAEVSKLEQQCQKQQEQADSLE 1147
Query: 144 DLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQED 203
L+A + + A + E+ A+EL ++ + R L + ED
Sbjct: 1148 RSLEAERASRAERDSALETLQGQLEEKAQELGHSQSALASAQRELAAFRTKVQDHSKAED 1207
Query: 204 LFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLK 263
+ ++++ RG ++ L +SL+ R EK+ + +AE+ S K
Sbjct: 1208 ---EWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRLVMAESEKSQK 1264
Query: 264 SEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVR 323
E ERL+ T ++ +R E L E ++ R + Q Q E
Sbjct: 1265 LE-ERLRLLQAETASNSARAAERSSALREEVQSLREEAEKQRVASENLRQELTSQAERAE 1323
Query: 324 KCLQTTVAELERQLAASRAQVSTAEKE 350
+ Q A E+ +A +ST + E
Sbjct: 1324 ELGQELKAWQEKFFQKEQA-LSTLQLE 1349
Score = 38.3 bits (85), Expect = 0.049
Identities = 75/370 (20%), Positives = 143/370 (38%), Gaps = 31/370 (8%)
Query: 22 ETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKE 81
+ Q + EL K E L ++++ E + V L+ R +++ E + +E
Sbjct: 640 QAQREKAELSRKVEELQACVET---ARQEQHEAQAQVAELELQLRSEQQKATEKERVAQE 696
Query: 82 QN---DQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQE 138
++ +QLQ + + +EE++R+ R ++ E + + + + + +E
Sbjct: 697 KDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAETRSLVEQHKRERKE 756
Query: 139 LAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMT 198
L K + RL+ +A + E L REL A LV +
Sbjct: 757 LEEERAGRKGLEARLQQLGEAH---QAETEVLRREL--AEAMAAQHTAESECEQLVKEVA 811
Query: 199 LTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAEN 258
+E Q E G Q + L + + + EK + + Q++
Sbjct: 812 AWRERYEDSQQEEAQYGAMFQEQLMTLKEECEKARQELQE-AKEKVAGIESHSELQISRQ 870
Query: 259 NISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASR---ALQRA 315
++E+ L A++ R + E R Q+ + + L ++ T E +R +++A
Sbjct: 871 ----QNELAELHANLARALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVARLETLVRKA 926
Query: 316 HEQTETVRKCLQTTVAE--------LE----RQLAASRAQVSTAEKEREELKNRLHWQMK 363
EQ ET + L A LE RQ +++A + E+E E++ N L
Sbjct: 927 GEQQETASRELVKEPARAGDRQPEWLEEQQGRQFCSTQAALQAMEREAEQMGNELERLRA 986
Query: 364 RLTENFEQAQ 373
L E+ Q Q
Sbjct: 987 ALMESQGQQQ 996
Score = 36.3 bits (80), Expect = 0.20
Identities = 30/148 (20%), Positives = 67/148 (45%), Gaps = 5/148 (3%)
Query: 246 ALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTR 305
A L +++ L +L + I++ + ++ A + +L + + + Q L
Sbjct: 494 ARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQQQEQASQGLRHQV 553
Query: 306 DEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRL 365
++ S +L++ +Q + V + + T + +QLA + + + +ER+ +L
Sbjct: 554 EQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALKQL-----EA 608
Query: 366 TENFEQAQLRILGLQTQVQSLRRTASST 393
E + A+L IL Q QV + R ++ T
Sbjct: 609 LEKEKAAKLEILQQQLQVANEARDSAQT 636
Score = 35.9 bits (79), Expect = 0.26
Identities = 72/404 (17%), Positives = 156/404 (38%), Gaps = 26/404 (6%)
Query: 22 ETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKE 81
+ + K +EL LA+ L + + + K R+E + +L+
Sbjct: 1170 QLEEKAQELGHSQSALASAQRELAAFRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISS 1229
Query: 82 QNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINL-------EIQRVKLKFQE 134
+++ + L+ + +E +R + ++ E++ L R +
Sbjct: 1230 LEEEVSILNRQVLEKEGESKELKRLVMAESEKSQKLEERLRLLQAETASNSARAAERSSA 1289
Query: 135 KLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLV 194
+E+ + + + ++ ++ +Q AE+L +EL +EK + L +L L
Sbjct: 1290 LREEVQSLREEAEKQRVASENLRQELTSQAERAEELGQELKAWQEKFFQKEQALSTLQLE 1349
Query: 195 TTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQ 254
T T ++ + +Q H + + GG ++ + + +
Sbjct: 1350 HTSTQALVSELLPAKHLCQQLQAEQAAAEKRHRE-ELEQSKQAAGGLRAELLRAQRELGE 1408
Query: 255 LAENNISLKSEIERLKASVIRTEESALANEKRLQEKMH-----ECAQLGGELDRTRD--- 306
L + +E ER A +R E+++ A + + +K H E LG + R
Sbjct: 1409 LIPLRQKV-AEQER-TAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLE 1466
Query: 307 -EASRALQRAHEQTETVRKCLQTTVAELER--QLAASRAQVSTAEKEREELK-----NRL 358
E +A ++ ++ VR +T +AE++R Q A +V TA+ E ++K R
Sbjct: 1467 VELDQAREKYVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKVKVLEERQRF 1526
Query: 359 HWQMKRLTENFEQAQLRILGLQTQVQSLRRTASSTGDGDGENQE 402
+ ++LT EQ ++ QV+ L + + + Q+
Sbjct: 1527 QEERQKLTAQVEQLEVFQREQTKQVEELSKKLADSDQASKVQQQ 1570
Score = 34.3 bits (75), Expect = 0.80
Identities = 36/143 (25%), Positives = 62/143 (43%), Gaps = 4/143 (2%)
Query: 36 GLATHTNMLMGSKEQAFEQ--EVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKY 93
GL N+ E +Q E V+ L +A + E++ + +L+ KY
Sbjct: 1453 GLGERANLGRQFLEVELDQAREKYVQELAAVRADAETRLAEVQREAQSTARELEVMTAKY 1512
Query: 94 LQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKL-QELAPIPDLLKATQMR 152
A+ V E+R++ T EQ+ + QR + K E+L ++LA K Q +
Sbjct: 1513 EGAKVKVLEERQRFQEERQKLTAQVEQLEV-FQREQTKQVEELSKKLADSDQASKVQQQK 1571
Query: 153 LKDAQQAQAIAEHNAEQLARELN 175
LK Q ++ A++L +LN
Sbjct: 1572 LKAVQAQGGESQQEAQRLQAQLN 1594
Score = 33.5 bits (73), Expect = 1.4
Identities = 40/167 (23%), Positives = 80/167 (47%), Gaps = 18/167 (10%)
Query: 229 LKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQ 288
L+P E R +E L++ + Q + KS+++R K + + E L+ +L+
Sbjct: 273 LEPKELEELRDKNESLTMRLHETLKQCQDLKTE-KSQMDR-KINQLSEENGDLSF--KLR 328
Query: 289 EKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAE 348
E QL L+ +E S+A Q E+ A+LE++L+A+ E
Sbjct: 329 EFASHLQQLQDALNELTEEHSKATQEWLEKQ-----------AQLEKELSAALQDKKCLE 377
Query: 349 KEREELK---NRLHWQMKRLTENFEQAQLRILGLQTQVQSLRRTASS 392
++ E L+ ++L + +L +N Q + +LG Q+++L++ A++
Sbjct: 378 EKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQEAAT 424
>BC103765-1|AAI03766.1| 691|Homo sapiens NUMA1 protein protein.
Length = 691
Score = 64.9 bits (151), Expect = 5e-10
Identities = 44/180 (24%), Positives = 80/180 (44%)
Query: 207 QSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEI 266
+ ++EI +G Q L PP++ E GD Q+ L Q + LA NN L++ +
Sbjct: 377 EEKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQEAATLAANNTQLQARV 436
Query: 267 ERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCL 326
E L+ + E LA +E+ + + L +L + S+A + + ++ L
Sbjct: 437 EMLETERGQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQAKEELEQASQAHGARL 496
Query: 327 QTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSL 386
VA L +L A + ++E LK + + +L + +Q + GL+ QV+ L
Sbjct: 497 TAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQQQEQASQGLRHQVEQL 556
Score = 36.3 bits (80), Expect = 0.20
Identities = 30/148 (20%), Positives = 67/148 (45%), Gaps = 5/148 (3%)
Query: 246 ALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTR 305
A L +++ L +L + I++ + ++ A + +L + + + Q L
Sbjct: 494 ARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQQQEQASQGLRHQV 553
Query: 306 DEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRL 365
++ S +L++ +Q + V + + T + +QLA + + + +ER+ +L
Sbjct: 554 EQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALKQL-----EA 608
Query: 366 TENFEQAQLRILGLQTQVQSLRRTASST 393
E + A+L IL Q QV + R ++ T
Sbjct: 609 LEKEKAAKLEILQQQLQVANEARDSAQT 636
Score = 33.5 bits (73), Expect = 1.4
Identities = 40/167 (23%), Positives = 80/167 (47%), Gaps = 18/167 (10%)
Query: 229 LKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQ 288
L+P E R +E L++ + Q + KS+++R K + + E L+ +L+
Sbjct: 273 LEPKELEELRDKNESLTMRLHETLKQCQDLKTE-KSQMDR-KINQLSEENGDLSF--KLR 328
Query: 289 EKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAE 348
E QL L+ +E S+A Q E+ A+LE++L+A+ E
Sbjct: 329 EFASHLQQLQDALNELTEEHSKATQEWLEKQ-----------AQLEKELSAALQDKKCLE 377
Query: 349 KEREELK---NRLHWQMKRLTENFEQAQLRILGLQTQVQSLRRTASS 392
++ E L+ ++L + +L +N Q + +LG Q+++L++ A++
Sbjct: 378 EKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQEAAT 424
>BC027493-1|AAH27493.1| 691|Homo sapiens Unknown (protein for
IMAGE:4540541) protein.
Length = 691
Score = 64.9 bits (151), Expect = 5e-10
Identities = 44/180 (24%), Positives = 80/180 (44%)
Query: 207 QSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEI 266
+ ++EI +G Q L PP++ E GD Q+ L Q + LA NN L++ +
Sbjct: 377 EEKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQEAATLAANNTQLQARV 436
Query: 267 ERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCL 326
E L+ + E LA +E+ + + L +L + S+A + + ++ L
Sbjct: 437 EMLETERGQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQAKEELEQASQAHGARL 496
Query: 327 QTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSL 386
VA L +L A + ++E LK + + +L + +Q + GL+ QV+ L
Sbjct: 497 TAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQQQEQASQGLRHQVEQL 556
Score = 36.3 bits (80), Expect = 0.20
Identities = 30/148 (20%), Positives = 67/148 (45%), Gaps = 5/148 (3%)
Query: 246 ALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTR 305
A L +++ L +L + I++ + ++ A + +L + + + Q L
Sbjct: 494 ARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQQQEQASQGLRHQV 553
Query: 306 DEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRL 365
++ S +L++ +Q + V + + T + +QLA + + + +ER+ +L
Sbjct: 554 EQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALKQL-----EA 608
Query: 366 TENFEQAQLRILGLQTQVQSLRRTASST 393
E + A+L IL Q QV + R ++ T
Sbjct: 609 LEKEKAAKLEILQQQLQVANEARDSAQT 636
Score = 33.5 bits (73), Expect = 1.4
Identities = 40/167 (23%), Positives = 80/167 (47%), Gaps = 18/167 (10%)
Query: 229 LKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQ 288
L+P E R +E L++ + Q + KS+++R K + + E L+ +L+
Sbjct: 273 LEPKELEELRDKNESLTMRLHETLKQCQDLKTE-KSQMDR-KINQLSEENGDLSF--KLR 328
Query: 289 EKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAE 348
E QL L+ +E S+A Q E+ A+LE++L+A+ E
Sbjct: 329 EFASHLQQLQDALNELTEEHSKATQEWLEKQ-----------AQLEKELSAALQDKKCLE 377
Query: 349 KEREELK---NRLHWQMKRLTENFEQAQLRILGLQTQVQSLRRTASS 392
++ E L+ ++L + +L +N Q + +LG Q+++L++ A++
Sbjct: 378 EKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQEAAT 424
>AB210007-1|BAE06089.1| 2121|Homo sapiens NUMA1 variant protein
protein.
Length = 2121
Score = 64.9 bits (151), Expect = 5e-10
Identities = 44/180 (24%), Positives = 80/180 (44%)
Query: 207 QSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEI 266
+ ++EI +G Q L PP++ E GD Q+ L Q + LA NN L++ +
Sbjct: 383 EEKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQEAATLAANNTQLQARV 442
Query: 267 ERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCL 326
E L+ + E LA +E+ + + L +L + S+A + + ++ L
Sbjct: 443 EMLETERGQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQAKEELEQASQAHGARL 502
Query: 327 QTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSL 386
VA L +L A + ++E LK + + +L + +Q + GL+ QV+ L
Sbjct: 503 TAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQQQEQASQGLRHQVEQL 562
Score = 42.3 bits (95), Expect = 0.003
Identities = 79/379 (20%), Positives = 157/379 (41%), Gaps = 17/379 (4%)
Query: 26 KLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQ 85
+++E E++ + LA + L K A +EV L+ R+A E+ + + ++ +
Sbjct: 893 QVQEKEVRAQKLADDLSTLQ-EKMAATSKEV--ARLETLVRKAGEQQETASRELVKEPAR 949
Query: 86 LQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDL 145
D + ++L+ QQ Q R +EQ+ E++R++ E +
Sbjct: 950 AGDRQPEWLEEQQ--GRQFCSTQAALQAMEREAEQMGNELERLRAALMESQGQQQEERGQ 1007
Query: 146 LKATQMRLKDAQQAQAIAEHNAEQLAR-ELNCAREKVVHIFRYLYS-LYLVTTMTLTQED 203
+ RL ++ +A A+ E+ AR EL + ++ R ++ L LT+++
Sbjct: 1008 QEREVARLTQ-ERGRAQADLALEKAARAELEMRLQNALNEQRVEFATLQEALAHALTEKE 1066
Query: 204 LFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLK 263
Q +++ RG + + L + + EK+ A + S+ A
Sbjct: 1067 GKDQELAKL-RGLEAAQIKELEELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTG 1125
Query: 264 SEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVR 323
++E L+A V + E+ +++ + + + RD A LQ E+
Sbjct: 1126 PKLEALRAEVSKLEQQCQKQQEQA-DSLERSLEAERASRAERDSALETLQGQLEEKAQEL 1184
Query: 324 KCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQLRILGLQTQV 383
Q+ +A +R+LAA R +V K +E K Q+ R + E+ I L+ +V
Sbjct: 1185 GHSQSALASAQRELAAFRTKVQDHSKAEDEWKA----QVARGRQEAERKNSLISSLEEEV 1240
Query: 384 QSLRRTASSTGDGDGENQE 402
L R + +GE++E
Sbjct: 1241 SILNRQVL---EKEGESKE 1256
Score = 40.3 bits (90), Expect = 0.012
Identities = 77/342 (22%), Positives = 140/342 (40%), Gaps = 25/342 (7%)
Query: 53 EQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXX 112
+Q+ + LKQ +E + ++ + +EQ Q ++V+ L + +EQ+ +
Sbjct: 522 QQDQELAGLKQQAKEKQAQLAQTLQ-QQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQ 580
Query: 113 XNTRI--SEQINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQL 170
TR ++Q+ + + +E+ L + L K +L+ QQ +A +
Sbjct: 581 EATRQDHAQQLATAAEEREASLRERDAALKQLEALEKEKAAKLEILQQQLQVANEARDSA 640
Query: 171 ARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLK 230
+ A+ + + R + L T QE ++Q+++ L K
Sbjct: 641 QTSVTQAQREKAELSRKVEELQACVE-TARQEQ--HEAQAQVAELELQ-----LRSEQQK 692
Query: 231 PPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKR-LQE 289
EK ER EK L +++ L E+ K +E K R AL ++R + E
Sbjct: 693 ATEK--ERVAQEKDQ--LQEQLQALKESLKVTKGSLEEEK----RRAADALEEQQRCISE 744
Query: 290 KMHECAQLGGELDRTRDEAS--RALQRAHE-QTETVRKCLQTTVAELERQLAASRAQVST 346
E L + R R E RA ++ E + + + + Q L R+LA + A T
Sbjct: 745 LKAETRSLVEQHKRERKELEEERAGRKGLEARLQQLGEAHQAETEVLRRELAEAMAAQHT 804
Query: 347 AEKEREEL-KNRLHWQMKRLTENFEQAQLRILGLQTQVQSLR 387
AE E E+L K W+ + E+AQ + Q Q+ +L+
Sbjct: 805 AESECEQLVKEVAAWRERYEDSQQEEAQYGAM-FQEQLMTLK 845
Score = 40.3 bits (90), Expect = 0.012
Identities = 70/330 (21%), Positives = 136/330 (41%), Gaps = 37/330 (11%)
Query: 53 EQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXX 112
E + R+L + ++ R+E++E R K +LQ + +++ + +
Sbjct: 744 ELKAETRSLVEQHKRERKELEEERAGRKGLEARLQQLGEAHQAETEVLRRELAEAMAAQH 803
Query: 113 XNTRISEQINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLK--------DAQQAQ---- 160
EQ+ E+ + ++++ QE A + + M LK + Q+A+
Sbjct: 804 TAESECEQLVKEVAAWRERYEDSQQEEAQYGAMFQEQLMTLKEECEKARQELQEAKEKVA 863
Query: 161 AIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKD-Q 219
I H+ Q++R+ N E ++ R L + D Q ++ +K+
Sbjct: 864 GIESHSELQISRQQNELAELHANLARALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVA 923
Query: 220 TVHVLLHNSLKPPE-------KPPERGGDEKQMALLNQRISQLAENNISLK--------- 263
+ L+ + + E K P R GD + L Q+ Q +L+
Sbjct: 924 RLETLVRKAGEQQETASRELVKEPARAGDRQPEWLEEQQGRQFCSTQAALQAMEREAEQM 983
Query: 264 -SEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETV 322
+E+ERL+A+++ E E+R Q++ E A+L E R R +A AL++A +
Sbjct: 984 GNELERLRAALM--ESQGQQQEERGQQE-REVARLTQE--RGRAQADLALEKAARAELEM 1038
Query: 323 RKCLQTTVAELERQLAASRAQVSTAEKERE 352
R LQ + E + A + ++ A E+E
Sbjct: 1039 R--LQNALNEQRVEFATLQEALAHALTEKE 1066
Score = 38.7 bits (86), Expect = 0.037
Identities = 75/347 (21%), Positives = 147/347 (42%), Gaps = 27/347 (7%)
Query: 60 ALKQCYREARE---EIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTR 116
AL+ REA + E++ LR + E Q Q+ R + + + ++R +
Sbjct: 972 ALQAMEREAEQMGNELERLRAALMESQGQQQEERGQQEREVARLTQERGRAQADLALEKA 1031
Query: 117 ISEQINLEIQRVKLKFQEKLQELAPIPDLLK--ATQMRLKDAQQAQAIAEHNAEQLAREL 174
++ + +Q E+ E A + + L T+ KD + A+ + A Q+ +EL
Sbjct: 1032 ARAELEMRLQNA---LNEQRVEFATLQEALAHALTEKEGKDQELAK-LRGLEAAQI-KEL 1086
Query: 175 NCAREKVVHIFRYLYSLYLV-TTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPE 233
R+ V + L + + Q + G+++ G K + + + + +
Sbjct: 1087 EELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPT---GPKLEALRAEVSKLEQQCQ 1143
Query: 234 KPPERGGDEKQMALLNQRISQLAENNI--SLKSEIERLKASVIRTEESALANEKRLQEKM 291
K E+ D + +L +R S+ ++ +L+ ++E KA + +SALA+ +R
Sbjct: 1144 KQQEQA-DSLERSLEAERASRAERDSALETLQGQLEE-KAQELGHSQSALASAQRELAAF 1201
Query: 292 HECAQLGGEL-DRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQ------V 344
Q + D + + +R Q A E+ ++ L+ V+ L RQ+ + +
Sbjct: 1202 RTKVQDHSKAEDEWKAQVARGRQEA-ERKNSLISSLEEEVSILNRQVLEKEGESKELKRL 1260
Query: 345 STAEKER-EELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRRTA 390
AE E+ ++L+ RL N +A R L+ +VQSLR A
Sbjct: 1261 VMAESEKSQKLEERLRLLQAETASNSARAAERSSALREEVQSLREEA 1307
Score = 38.7 bits (86), Expect = 0.037
Identities = 64/327 (19%), Positives = 127/327 (38%), Gaps = 12/327 (3%)
Query: 24 QNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQN 83
QN L E ++F L + KE ++ +R L+ +E++ELR +K+
Sbjct: 1041 QNALNEQRVEFATLQEALAHALTEKEGKDQELAKLRGLEAA---QIKELEELRQTVKQLK 1097
Query: 84 DQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIP 143
+QL ++ Q ++ E + E+ +++ + Q++ ++ +
Sbjct: 1098 EQLAKKEKEHASGS---GAQSEAAGRTEPTGPKL-EALRAEVSKLEQQCQKQQEQADSLE 1153
Query: 144 DLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQED 203
L+A + + A + E+ A+EL ++ + R L + ED
Sbjct: 1154 RSLEAERASRAERDSALETLQGQLEEKAQELGHSQSALASAQRELAAFRTKVQDHSKAED 1213
Query: 204 LFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLK 263
+ ++++ RG ++ L +SL+ R EK+ + +AE+ S K
Sbjct: 1214 ---EWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRLVMAESEKSQK 1270
Query: 264 SEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVR 323
E ERL+ T ++ +R E L E ++ R + Q Q E
Sbjct: 1271 LE-ERLRLLQAETASNSARAAERSSALREEVQSLREEAEKQRVASENLRQELTSQAERAE 1329
Query: 324 KCLQTTVAELERQLAASRAQVSTAEKE 350
+ Q A E+ +A +ST + E
Sbjct: 1330 ELGQELKAWQEKFFQKEQA-LSTLQLE 1355
Score = 38.3 bits (85), Expect = 0.049
Identities = 75/370 (20%), Positives = 143/370 (38%), Gaps = 31/370 (8%)
Query: 22 ETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKE 81
+ Q + EL K E L ++++ E + V L+ R +++ E + +E
Sbjct: 646 QAQREKAELSRKVEELQACVET---ARQEQHEAQAQVAELELQLRSEQQKATEKERVAQE 702
Query: 82 QN---DQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQE 138
++ +QLQ + + +EE++R+ R ++ E + + + + + +E
Sbjct: 703 KDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAETRSLVEQHKRERKE 762
Query: 139 LAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMT 198
L K + RL+ +A + E L REL A LV +
Sbjct: 763 LEEERAGRKGLEARLQQLGEAH---QAETEVLRREL--AEAMAAQHTAESECEQLVKEVA 817
Query: 199 LTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAEN 258
+E Q E G Q + L + + + EK + + Q++
Sbjct: 818 AWRERYEDSQQEEAQYGAMFQEQLMTLKEECEKARQELQE-AKEKVAGIESHSELQISRQ 876
Query: 259 NISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASR---ALQRA 315
++E+ L A++ R + E R Q+ + + L ++ T E +R +++A
Sbjct: 877 ----QNELAELHANLARALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVARLETLVRKA 932
Query: 316 HEQTETVRKCLQTTVAE--------LE----RQLAASRAQVSTAEKEREELKNRLHWQMK 363
EQ ET + L A LE RQ +++A + E+E E++ N L
Sbjct: 933 GEQQETASRELVKEPARAGDRQPEWLEEQQGRQFCSTQAALQAMEREAEQMGNELERLRA 992
Query: 364 RLTENFEQAQ 373
L E+ Q Q
Sbjct: 993 ALMESQGQQQ 1002
Score = 36.3 bits (80), Expect = 0.20
Identities = 30/148 (20%), Positives = 67/148 (45%), Gaps = 5/148 (3%)
Query: 246 ALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTR 305
A L +++ L +L + I++ + ++ A + +L + + + Q L
Sbjct: 500 ARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQQQEQASQGLRHQV 559
Query: 306 DEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRL 365
++ S +L++ +Q + V + + T + +QLA + + + +ER+ +L
Sbjct: 560 EQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALKQL-----EA 614
Query: 366 TENFEQAQLRILGLQTQVQSLRRTASST 393
E + A+L IL Q QV + R ++ T
Sbjct: 615 LEKEKAAKLEILQQQLQVANEARDSAQT 642
Score = 35.9 bits (79), Expect = 0.26
Identities = 72/404 (17%), Positives = 156/404 (38%), Gaps = 26/404 (6%)
Query: 22 ETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKE 81
+ + K +EL LA+ L + + + K R+E + +L+
Sbjct: 1176 QLEEKAQELGHSQSALASAQRELAAFRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISS 1235
Query: 82 QNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINL-------EIQRVKLKFQE 134
+++ + L+ + +E +R + ++ E++ L R +
Sbjct: 1236 LEEEVSILNRQVLEKEGESKELKRLVMAESEKSQKLEERLRLLQAETASNSARAAERSSA 1295
Query: 135 KLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLV 194
+E+ + + + ++ ++ +Q AE+L +EL +EK + L +L L
Sbjct: 1296 LREEVQSLREEAEKQRVASENLRQELTSQAERAEELGQELKAWQEKFFQKEQALSTLQLE 1355
Query: 195 TTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQ 254
T T ++ + +Q H + + GG ++ + + +
Sbjct: 1356 HTSTQALVSELLPAKHLCQQLQAEQAAAEKRHRE-ELEQSKQAAGGLRAELLRAQRELGE 1414
Query: 255 LAENNISLKSEIERLKASVIRTEESALANEKRLQEKMH-----ECAQLGGELDRTRD--- 306
L + +E ER A +R E+++ A + + +K H E LG + R
Sbjct: 1415 LIPLRQKV-AEQER-TAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLE 1472
Query: 307 -EASRALQRAHEQTETVRKCLQTTVAELER--QLAASRAQVSTAEKEREELK-----NRL 358
E +A ++ ++ VR +T +AE++R Q A +V TA+ E ++K R
Sbjct: 1473 VELDQAREKYVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKVKVLEERQRF 1532
Query: 359 HWQMKRLTENFEQAQLRILGLQTQVQSLRRTASSTGDGDGENQE 402
+ ++LT EQ ++ QV+ L + + + Q+
Sbjct: 1533 QEERQKLTAQVEQLEVFQREQTKQVEELSKKLADSDQASKVQQQ 1576
Score = 34.3 bits (75), Expect = 0.80
Identities = 36/143 (25%), Positives = 62/143 (43%), Gaps = 4/143 (2%)
Query: 36 GLATHTNMLMGSKEQAFEQ--EVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKY 93
GL N+ E +Q E V+ L +A + E++ + +L+ KY
Sbjct: 1459 GLGERANLGRQFLEVELDQAREKYVQELAAVRADAETRLAEVQREAQSTARELEVMTAKY 1518
Query: 94 LQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKL-QELAPIPDLLKATQMR 152
A+ V E+R++ T EQ+ + QR + K E+L ++LA K Q +
Sbjct: 1519 EGAKVKVLEERQRFQEERQKLTAQVEQLEV-FQREQTKQVEELSKKLADSDQASKVQQQK 1577
Query: 153 LKDAQQAQAIAEHNAEQLARELN 175
LK Q ++ A++L +LN
Sbjct: 1578 LKAVQAQGGESQQEAQRLQAQLN 1600
Score = 33.5 bits (73), Expect = 1.4
Identities = 40/167 (23%), Positives = 80/167 (47%), Gaps = 18/167 (10%)
Query: 229 LKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQ 288
L+P E R +E L++ + Q + KS+++R K + + E L+ +L+
Sbjct: 279 LEPKELEELRDKNESLTMRLHETLKQCQDLKTE-KSQMDR-KINQLSEENGDLSF--KLR 334
Query: 289 EKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAE 348
E QL L+ +E S+A Q E+ A+LE++L+A+ E
Sbjct: 335 EFASHLQQLQDALNELTEEHSKATQEWLEKQ-----------AQLEKELSAALQDKKCLE 383
Query: 349 KEREELK---NRLHWQMKRLTENFEQAQLRILGLQTQVQSLRRTASS 392
++ E L+ ++L + +L +N Q + +LG Q+++L++ A++
Sbjct: 384 EKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQEAAT 430
>BC012785-1|AAH12785.1| 174|Homo sapiens ODF2 protein protein.
Length = 174
Score = 64.5 bits (150), Expect = 7e-10
Identities = 35/156 (22%), Positives = 79/156 (50%), Gaps = 1/156 (0%)
Query: 242 EKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGEL 301
+K+ L+ ++ +L + ++ + + EE+ ++ RL+EK EC L +L
Sbjct: 1 QKENKQLSLKVDELERKLEATSAQNIEFLQVIAKREEAIHQSQLRLEEKTRECGTLARQL 60
Query: 302 DRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQ 361
+ ++A R +++ E + + Q + +LE QL+ ++ ++S + R++ R +
Sbjct: 61 ESAIEDARRQVEQTKEHALSKERAAQNKILDLETQLSRTKTELSQLRRSRDDADRRYQSR 120
Query: 362 MKRLTENFEQAQLRILGLQTQVQSLRRT-ASSTGDG 396
++ L + EQ++ +Q VQ L+ + A+ GDG
Sbjct: 121 LQDLKDRLEQSESTNRSMQNYVQFLKSSYANVFGDG 156
>AK126816-1|BAC86706.1| 235|Homo sapiens protein ( Homo sapiens
cDNA FLJ44866 fis, clone BRALZ2014054, moderately
similar to Rattus norvegicus cenexin 2. ).
Length = 235
Score = 63.3 bits (147), Expect = 2e-09
Identities = 32/125 (25%), Positives = 67/125 (53%), Gaps = 1/125 (0%)
Query: 273 VIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAE 332
+ + EE+ ++ RL+EK EC L +L+ ++A R +++ E + + Q + +
Sbjct: 93 IAKREEAIHQSQLRLEEKTRECGTLARQLESAIEDARRQVEQTKEHALSKERAAQNKILD 152
Query: 333 LERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRRT-AS 391
LE QL+ ++ ++S + R++ R +++ L + EQ++ +Q VQ L+ + A+
Sbjct: 153 LETQLSRTKTELSQLRRSRDDADRRYQSRLQDLKDRLEQSESTNRSMQNYVQFLKSSYAN 212
Query: 392 STGDG 396
GDG
Sbjct: 213 VFGDG 217
>AF111783-1|AAD29949.1| 1939|Homo sapiens myosin heavy chain IIb
protein.
Length = 1939
Score = 60.1 bits (139), Expect = 1e-08
Identities = 83/339 (24%), Positives = 147/339 (43%), Gaps = 37/339 (10%)
Query: 38 ATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQND---QLQDYRVKYL 94
+ T M + ++ FE+ A + R+ EE ++ TLM+E+ND Q+Q
Sbjct: 846 SAETEKEMANMKEEFEKTKEELAKTEAKRKELEE--KMVTLMQEKNDLQLQVQAEADALA 903
Query: 95 QAQ----QLVEEQRRQXXXXXXXNTRIS--EQINLEIQRVKLKFQEKLQELAPIPDLLKA 148
A+ QL++ + + R E+IN E+ K K +++ EL D L+
Sbjct: 904 DAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLEL 963
Query: 149 TQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQS 208
T +++ + A E+ + L E+ E + + + +L TL +DL
Sbjct: 964 TLAKVEKEKHA---TENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTL--DDL---- 1014
Query: 209 QSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIER 268
Q E + N L + E E+ EK++ + +R + E ++ L E
Sbjct: 1015 QMEEDKVNTLTKAKTKLEQQVDDLEGSLEQ---EKKLCMDLERAKRKLEGDLKLAQE--- 1068
Query: 269 LKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQT 328
S + TE ++L++K E + L G+++ DE + A+Q + E LQ
Sbjct: 1069 ---STMDTENDKQQLNEKLKKKEFEMSNLQGKIE---DEQALAMQLQKKIKE-----LQA 1117
Query: 329 TVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTE 367
+ ELE ++ A RA + AEK+R +L L +RL E
Sbjct: 1118 RIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEE 1156
Score = 41.1 bits (92), Expect = 0.007
Identities = 79/391 (20%), Positives = 156/391 (39%), Gaps = 22/391 (5%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKEQAF----EQEVNVRALKQCYREAREEIDE 74
Q E + ELE + L + L S E+A +E + ++ + + EID
Sbjct: 1519 QIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLEHEEGKILRIQLELNQVKSEIDR 1578
Query: 75 LRTLMKEQNDQLQDYRVKYLQAQQ-LVEEQRRQXXXXXXXNTRISEQIN-LEIQ--RVKL 130
E+ DQL+ ++ +++ Q ++ + R ++ +N +EIQ
Sbjct: 1579 KIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKKKMEGDLNEMEIQLNHANR 1638
Query: 131 KFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYS 190
+ E L+ L +LK TQ+ L DA + Q + + R N + +V + L
Sbjct: 1639 QAAEALRNLRNTQGILKDTQLHLDDAIRGQDDLKEQLAMVERRANLMQAEVEELRASLER 1698
Query: 191 LYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQ 250
M +++L S+ R T + L N+ K E + E + +
Sbjct: 1699 TERGRKM--AEQELLDASE----RVQLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEA 1752
Query: 251 RISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASR 310
R AE + A ++ E+ A+ +R+++ M + + +L EA +
Sbjct: 1753 R---NAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVK---DLQLRLGEAEQ 1806
Query: 311 -ALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENF 369
AL+ +Q + + ++ +E+E + + V K +K L +Q + +N
Sbjct: 1807 LALKGGKKQIQKLEARVRELESEVESEQKHNVEAVKGLRKHERRVK-ELTYQTEEDRKNI 1865
Query: 370 EQAQLRILGLQTQVQSLRRTASSTGDGDGEN 400
+ Q + LQT+V++ +R A + N
Sbjct: 1866 LRLQDLVDKLQTKVKAYKRQAEEAEEQSNVN 1896
Score = 40.7 bits (91), Expect = 0.009
Identities = 37/134 (27%), Positives = 65/134 (48%), Gaps = 15/134 (11%)
Query: 241 DEKQMAL-LNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGG 299
DE+ +A+ L ++I +L L+ EIE +AS + E+ + L+E + GG
Sbjct: 1100 DEQALAMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGG 1159
Query: 300 ------ELDRTRDEASRALQR-------AHEQTET-VRKCLQTTVAELERQLAASRAQVS 345
EL++ R+ + ++R HE T +RK +VAEL +Q+ + +
Sbjct: 1160 ATSAQIELNKKREAEFQKMRRDLEESTLQHEATAAALRKKHADSVAELGKQIDSLQRVKQ 1219
Query: 346 TAEKEREELKNRLH 359
EKE+ ELK ++
Sbjct: 1220 KLEKEKSELKMEIN 1233
Score = 39.9 bits (89), Expect = 0.016
Identities = 67/378 (17%), Positives = 144/378 (38%), Gaps = 27/378 (7%)
Query: 22 ETQNKLRELEMKFEGLATHTNMLMGSKEQ----AFEQEVNVRALKQCYREAREEIDELRT 77
+T+N ++L K + + L G E A + + ++ L+ E EEI+ R
Sbjct: 1072 DTENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAMQLQKKIKELQARIEELEEEIEAERA 1131
Query: 78 LMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEK-L 136
+ Q D + + + +EE ++++ E Q+++ +E L
Sbjct: 1132 SRAKAEKQRSDLSRELEEISERLEE----AGGATSAQIELNKKREAEFQKMRRDLEESTL 1187
Query: 137 QELAPIPDLLKATQ-------MRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLY 189
Q A L K ++ Q+ + E +L E+N + + +
Sbjct: 1188 QHEATAAALRKKHADSVAELGKQIDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKA 1247
Query: 190 SLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLN 249
+ M T ED SEI ++Q ++ S + E G +Q+ +
Sbjct: 1248 NF---EKMCRTLEDQL----SEIKTKEEEQQ-RLINELSAQKARLHTESGEFSRQLDEKD 1299
Query: 250 QRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRD--- 306
+SQL+ + +IE LK + ++ LQ H+C L + + ++
Sbjct: 1300 AMVSQLSRGKQAFTQQIEELKRQLEEETKAKSTLAHALQSARHDCDLLREQYEEEQEAKA 1359
Query: 307 EASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLT 366
E R + +A+ + R +T + +L ++ +++ ++ EE ++ + L
Sbjct: 1360 ELQRGMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLE 1419
Query: 367 ENFEQAQLRILGLQTQVQ 384
+ ++ Q + L V+
Sbjct: 1420 KTKQRLQNEVEDLMIDVE 1437
>AL445287-5|CAH71068.1| 765|Homo sapiens outer dense fiber of sperm
tails 2 protein.
Length = 765
Score = 59.3 bits (137), Expect = 2e-08
Identities = 64/301 (21%), Positives = 127/301 (42%), Gaps = 11/301 (3%)
Query: 19 QHRETQNKLRE-LEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRT 77
Q + + K+RE + E L T K + + + ++ +A E+ +L+
Sbjct: 470 QQQTLEEKMREDRDSLVERLHRQTAEYSAFKLENERLKASFAPMEDKLNQAHLEVQQLKA 529
Query: 78 LMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQ 137
+K + +Y+ + ++ + +E Q N + +++N EI+ + +FQ +L
Sbjct: 530 SVKNYEGMIDNYKSQVMKTRLEADEVAAQLERCDKENKILKDEMNKEIEAARRQFQSQLA 589
Query: 138 ELAPIPDLLKATQMRLKDAQ-QAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTT 196
+L +PD+LK T+ +L + Q Q Q N + L ++ R ++ H L
Sbjct: 590 DLQQLPDILKITEAKLAECQDQLQGYERKNID-LTAIISDLRSRIEHQGDKLEMAREKHQ 648
Query: 197 MTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLA 256
+ + E+ R K + L+ K E + L ++ +
Sbjct: 649 ASQKENKQLSLKVDELER--KLEATSAQNIEFLQVIAKREE--AIHQSQLRLEEKTRECG 704
Query: 257 ENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAH 316
L+S IE + V +T+E AL+ E+ Q K+ L +L RT+ E S+ L+R+
Sbjct: 705 TLARQLESAIEDARRQVEQTKEHALSKERAAQNKI---LDLETQLSRTKTELSQ-LRRSR 760
Query: 317 E 317
+
Sbjct: 761 D 761
Score = 55.2 bits (127), Expect = 4e-07
Identities = 35/130 (26%), Positives = 68/130 (52%), Gaps = 12/130 (9%)
Query: 237 ERGGDEKQMALLNQRISQLAENNISLK-SEIER-LKAS----------VIRTEESALANE 284
E GD+ +MA + SQ +SLK E+ER L+A+ + + EE+ ++
Sbjct: 634 EHQGDKLEMAREKHQASQKENKQLSLKVDELERKLEATSAQNIEFLQVIAKREEAIHQSQ 693
Query: 285 KRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQV 344
RL+EK EC L +L+ ++A R +++ E + + Q + +LE QL+ ++ ++
Sbjct: 694 LRLEEKTRECGTLARQLESAIEDARRQVEQTKEHALSKERAAQNKILDLETQLSRTKTEL 753
Query: 345 STAEKEREEL 354
S + R+++
Sbjct: 754 SQLRRSRDDV 763
Score = 35.9 bits (79), Expect = 0.26
Identities = 77/389 (19%), Positives = 153/389 (39%), Gaps = 25/389 (6%)
Query: 20 HRETQNKLRELEMK--FEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRT 77
+R ++ LRE K E L L+ +A ++ + L Q + +E++EL
Sbjct: 262 NRTLRDLLREQHCKEDSERLMEQQGALLKRLAEADSEKARLLLLLQ---DKDKEVEELLQ 318
Query: 78 LMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQI-NLEIQ--RVKLKFQE 134
++ + Q + + + + Q N+R+ QI NLE + K + +
Sbjct: 319 EIQCEKAQAKTASELSKSMESMRGHLQAQLRSKEAENSRLCMQIKNLERSGNQHKAEVEA 378
Query: 135 KLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLV 194
+++L + + LK A +AQ +E+ A +L H+ LY+
Sbjct: 379 IMEQLKELKQKGDRDKESLKKAIRAQKERAEKSEEYAEQL--------HVQLADKDLYVA 430
Query: 195 TTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHN--SLKPPEKPPERGGDEKQMALLNQRI 252
++ + +Q +G+ + + VL L ++ E E + +L+ +
Sbjct: 431 EALSTLESWRSRYNQVVKEKGDLELEIIVLNDRVTDLVNQQQTLEEKMREDRDSLVERLH 490
Query: 253 SQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRAL 312
Q AE + + K E ERLKAS E+ +Q+ G +D + + +
Sbjct: 491 RQTAEYS-AFKLENERLKASFAPMEDKLNQAHLEVQQLKASVKNYEGMIDNYKSQVMKTR 549
Query: 313 QRAHEQTETVRKCLQTTVA---ELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENF 369
A E + +C + E+ +++ A+R Q + + ++L + L +L E
Sbjct: 550 LEADEVAAQLERCDKENKILKDEMNKEIEAARRQFQSQLADLQQLPDILKITEAKLAECQ 609
Query: 370 EQAQ---LRILGLQTQVQSLRRTASSTGD 395
+Q Q + + L + LR GD
Sbjct: 610 DQLQGYERKNIDLTAIISDLRSRIEHQGD 638
Score = 33.9 bits (74), Expect = 1.1
Identities = 35/146 (23%), Positives = 61/146 (41%), Gaps = 10/146 (6%)
Query: 244 QMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQ------- 296
+M +++I L LKSE++ K + ++ L+E HE A+
Sbjct: 114 KMNRYDKKIDSLMNAVGCLKSEVKMQKGERQMAKRFLEERKEELEEVAHELAETEHENTV 173
Query: 297 LGGELDRTRDEAS-RALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELK 355
L ++R ++E LQ+ H Q E ++CL + + E E AA+ QV + +LK
Sbjct: 174 LRHNIERMKEEKDFTILQKKHLQQE--KECLMSKLVEAEMDGAAAAKQVMALKDTIGKLK 231
Query: 356 NRLHWQMKRLTENFEQAQLRILGLQT 381
+ Q +L + L T
Sbjct: 232 TEKQMTCTDINTLTRQKELLLQKLST 257
>AL359091-22|CAI13505.1| 765|Homo sapiens outer dense fiber of
sperm tails 2 protein.
Length = 765
Score = 59.3 bits (137), Expect = 2e-08
Identities = 64/301 (21%), Positives = 127/301 (42%), Gaps = 11/301 (3%)
Query: 19 QHRETQNKLRE-LEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRT 77
Q + + K+RE + E L T K + + + ++ +A E+ +L+
Sbjct: 470 QQQTLEEKMREDRDSLVERLHRQTAEYSAFKLENERLKASFAPMEDKLNQAHLEVQQLKA 529
Query: 78 LMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQ 137
+K + +Y+ + ++ + +E Q N + +++N EI+ + +FQ +L
Sbjct: 530 SVKNYEGMIDNYKSQVMKTRLEADEVAAQLERCDKENKILKDEMNKEIEAARRQFQSQLA 589
Query: 138 ELAPIPDLLKATQMRLKDAQ-QAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTT 196
+L +PD+LK T+ +L + Q Q Q N + L ++ R ++ H L
Sbjct: 590 DLQQLPDILKITEAKLAECQDQLQGYERKNID-LTAIISDLRSRIEHQGDKLEMAREKHQ 648
Query: 197 MTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLA 256
+ + E+ R K + L+ K E + L ++ +
Sbjct: 649 ASQKENKQLSLKVDELER--KLEATSAQNIEFLQVIAKREE--AIHQSQLRLEEKTRECG 704
Query: 257 ENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAH 316
L+S IE + V +T+E AL+ E+ Q K+ L +L RT+ E S+ L+R+
Sbjct: 705 TLARQLESAIEDARRQVEQTKEHALSKERAAQNKI---LDLETQLSRTKTELSQ-LRRSR 760
Query: 317 E 317
+
Sbjct: 761 D 761
Score = 55.2 bits (127), Expect = 4e-07
Identities = 35/130 (26%), Positives = 68/130 (52%), Gaps = 12/130 (9%)
Query: 237 ERGGDEKQMALLNQRISQLAENNISLK-SEIER-LKAS----------VIRTEESALANE 284
E GD+ +MA + SQ +SLK E+ER L+A+ + + EE+ ++
Sbjct: 634 EHQGDKLEMAREKHQASQKENKQLSLKVDELERKLEATSAQNIEFLQVIAKREEAIHQSQ 693
Query: 285 KRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQV 344
RL+EK EC L +L+ ++A R +++ E + + Q + +LE QL+ ++ ++
Sbjct: 694 LRLEEKTRECGTLARQLESAIEDARRQVEQTKEHALSKERAAQNKILDLETQLSRTKTEL 753
Query: 345 STAEKEREEL 354
S + R+++
Sbjct: 754 SQLRRSRDDV 763
Score = 35.9 bits (79), Expect = 0.26
Identities = 77/389 (19%), Positives = 153/389 (39%), Gaps = 25/389 (6%)
Query: 20 HRETQNKLRELEMK--FEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRT 77
+R ++ LRE K E L L+ +A ++ + L Q + +E++EL
Sbjct: 262 NRTLRDLLREQHCKEDSERLMEQQGALLKRLAEADSEKARLLLLLQ---DKDKEVEELLQ 318
Query: 78 LMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQI-NLEIQ--RVKLKFQE 134
++ + Q + + + + Q N+R+ QI NLE + K + +
Sbjct: 319 EIQCEKAQAKTASELSKSMESMRGHLQAQLRSKEAENSRLCMQIKNLERSGNQHKAEVEA 378
Query: 135 KLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLV 194
+++L + + LK A +AQ +E+ A +L H+ LY+
Sbjct: 379 IMEQLKELKQKGDRDKESLKKAIRAQKERAEKSEEYAEQL--------HVQLADKDLYVA 430
Query: 195 TTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHN--SLKPPEKPPERGGDEKQMALLNQRI 252
++ + +Q +G+ + + VL L ++ E E + +L+ +
Sbjct: 431 EALSTLESWRSRYNQVVKEKGDLELEIIVLNDRVTDLVNQQQTLEEKMREDRDSLVERLH 490
Query: 253 SQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRAL 312
Q AE + + K E ERLKAS E+ +Q+ G +D + + +
Sbjct: 491 RQTAEYS-AFKLENERLKASFAPMEDKLNQAHLEVQQLKASVKNYEGMIDNYKSQVMKTR 549
Query: 313 QRAHEQTETVRKCLQTTVA---ELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENF 369
A E + +C + E+ +++ A+R Q + + ++L + L +L E
Sbjct: 550 LEADEVAAQLERCDKENKILKDEMNKEIEAARRQFQSQLADLQQLPDILKITEAKLAECQ 609
Query: 370 EQAQ---LRILGLQTQVQSLRRTASSTGD 395
+Q Q + + L + LR GD
Sbjct: 610 DQLQGYERKNIDLTAIISDLRSRIEHQGD 638
Score = 33.9 bits (74), Expect = 1.1
Identities = 35/146 (23%), Positives = 61/146 (41%), Gaps = 10/146 (6%)
Query: 244 QMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQ------- 296
+M +++I L LKSE++ K + ++ L+E HE A+
Sbjct: 114 KMNRYDKKIDSLMNAVGCLKSEVKMQKGERQMAKRFLEERKEELEEVAHELAETEHENTV 173
Query: 297 LGGELDRTRDEAS-RALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELK 355
L ++R ++E LQ+ H Q E ++CL + + E E AA+ QV + +LK
Sbjct: 174 LRHNIERMKEEKDFTILQKKHLQQE--KECLMSKLVEAEMDGAAAAKQVMALKDTIGKLK 231
Query: 356 NRLHWQMKRLTENFEQAQLRILGLQT 381
+ Q +L + L T
Sbjct: 232 TEKQMTCTDINTLTRQKELLLQKLST 257
>X13988-1|CAA32167.1| 1940|Homo sapiens protein ( Human mRNA for
embryonic myosin heavy chain. ).
Length = 1940
Score = 58.4 bits (135), Expect = 4e-08
Identities = 81/339 (23%), Positives = 148/339 (43%), Gaps = 37/339 (10%)
Query: 38 ATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQND---QLQDYRVKYL 94
+ T M + ++ F++ + A + R+ EE +L TL++E+ND Q+Q L
Sbjct: 843 SAETEKEMATMKEEFQKTKDELAKSEAKRKELEE--KLVTLVQEKNDLQLQVQAESENLL 900
Query: 95 QAQ----QLVEEQRRQXXXXXXXNTRIS--EQINLEIQRVKLKFQEKLQELAPIPDLLKA 148
A+ QL++ + + R E+IN E+ K K +++ EL D L+
Sbjct: 901 DAEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLEL 960
Query: 149 TQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQS 208
T +++ + A E+ + L EL+ E + + R +L L +DL
Sbjct: 961 TLAKVEKEKHA---TENKVKNLTEELSGLDETIAKLTREKKALQEAHQQAL--DDL---- 1011
Query: 209 QSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIER 268
Q+E + N L ++ E E+ EK++ + L N L+ +++
Sbjct: 1012 QAEEDKVNSLNKTKSKLEQQVEDLESSLEQ---EKKLRV------DLERNKRKLEGDLKL 1062
Query: 269 LKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQT 328
+ S++ E ++RL++K E QL +++ DE + LQ + E LQ
Sbjct: 1063 AQESILDLENDKQQLDERLKKKDFEYCQLQSKVE---DEQTLGLQFQKKIKE-----LQA 1114
Query: 329 TVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTE 367
+ ELE ++ A RA + EK+R + L +RL E
Sbjct: 1115 RIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEE 1153
Score = 52.0 bits (119), Expect = 4e-06
Identities = 65/343 (18%), Positives = 140/343 (40%), Gaps = 17/343 (4%)
Query: 58 VRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRI 117
++ L+ E EEI+ R + Q DY A++L E R +T+I
Sbjct: 1109 IKELQARIEELEEEIEAERATRAKTEKQRSDY------ARELEELSERLEEAGGVTSTQI 1162
Query: 118 SEQINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEH--NAEQLARELN 175
++N + + LK + L+E + + AT +R K A + E N +++ ++L
Sbjct: 1163 --ELNKKREAEFLKLRRDLEEATLQHEAMVAT-LRKKHADSVAELGEQIDNLQRVKQKLE 1219
Query: 176 CAREKV-VHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIG--RGNKDQTVHVLLHNSLKPP 232
+ + + I S+ V+ E + + ++ RG ++ L + +
Sbjct: 1220 KEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKS 1279
Query: 233 EKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMH 292
E G +Q+ +SQL+ + + + E LK + ++ A LQ H
Sbjct: 1280 RLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRH 1339
Query: 293 ECAQLGGELDRTRD---EASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEK 349
+C L + + ++ E RAL +A+ + R +T + +L ++ +++ +
Sbjct: 1340 DCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAQEKLAQRLQ 1399
Query: 350 EREELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRRTASS 392
+ EE ++ + L + ++ Q + L V+ A++
Sbjct: 1400 DSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAA 1442
Score = 42.3 bits (95), Expect = 0.003
Identities = 80/397 (20%), Positives = 162/397 (40%), Gaps = 42/397 (10%)
Query: 27 LRELEMKFEGL-ATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQ 85
L E ++ E + AT S + EQ N++ +KQ + +E E + + + +
Sbjct: 1179 LEEATLQHEAMVATLRKKHADSVAELGEQIDNLQRVKQ---KLEKEKSEFKLEIDDLSSS 1235
Query: 86 LQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDL 145
++ +++ Q N I ++ E+ K + Q + EL+ +
Sbjct: 1236 MESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLS-ELTTQKSRLQTEAGELSRQLEE 1294
Query: 146 LKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYL-YSLYLVTTMTLTQEDL 204
++ +L ++QA ++ E N A+ + H + + L+ +++
Sbjct: 1295 KESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEG 1354
Query: 205 FGQSQSEIGRGNKD--------QTVHVLLHNSLKPP-EKPPERGGD-EKQMALLNQRISQ 254
+ Q + + N + +T + L+ EK +R D E+Q+ +N + +
Sbjct: 1355 KAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAQEKLAQRLQDSEEQVEAVNAKCAS 1414
Query: 255 LAENNISLKSEIERLKASVIRTEESALANEKR-------LQEKMHECAQLGGELDRTRDE 307
L + L+ E+E L V R A A +K+ L E +C + EL+ + E
Sbjct: 1415 LEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKE 1474
Query: 308 A----------SRALQRAHEQTETVR---KCLQTTVAELERQLAASRAQVSTAEKEREEL 354
+ A + A +Q ETV+ K L+ +A+L Q+A + + EK R+++
Sbjct: 1475 SRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQI 1534
Query: 355 ---KNRLHWQMKRLTENFEQAQLRILGLQ---TQVQS 385
K + ++ E + +IL +Q TQV+S
Sbjct: 1535 ELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKS 1571
Score = 36.3 bits (80), Expect = 0.20
Identities = 70/325 (21%), Positives = 132/325 (40%), Gaps = 33/325 (10%)
Query: 52 FEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXX 111
F+ E ++ + + + E EL ++ D+ + + + + + ++
Sbjct: 914 FQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATE 973
Query: 112 XXNTRISEQIN-LEIQRVKLKFQEK-LQEL-APIPDLLKATQMRLKDAQQAQAIAEHNAE 168
++E+++ L+ KL ++K LQE D L+A + ++ + ++ E E
Sbjct: 974 NKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVE 1033
Query: 169 QLARELNCAREKVVHIFRYLYSLYLVTTMTLTQE---DLFGQSQSEIGRGNKDQTVHVLL 225
L L +EK + + L + L QE DL Q R K + L
Sbjct: 1034 DLESSLE--QEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQL 1091
Query: 226 HNSLKPPEKPPERGGDEKQMAL-LNQRISQLAENNISLKSEIERLKASVIRTEESALANE 284
+ ++ DE+ + L ++I +L L+ EIE +A+ +TE+
Sbjct: 1092 QSKVE----------DEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYA 1141
Query: 285 KRLQEKMHECAQLGG------ELDRTRD----EASRALQRA---HE-QTETVRKCLQTTV 330
+ L+E + GG EL++ R+ + R L+ A HE T+RK +V
Sbjct: 1142 RELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVATLRKKHADSV 1201
Query: 331 AELERQLAASRAQVSTAEKEREELK 355
AEL Q+ + EKE+ E K
Sbjct: 1202 AELGEQIDNLQRVKQKLEKEKSEFK 1226
Score = 34.7 bits (76), Expect = 0.60
Identities = 72/379 (18%), Positives = 149/379 (39%), Gaps = 23/379 (6%)
Query: 48 KEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVE---EQR 104
K + E + + A + R E+ +L+ +E DQL+ + + +Q + EQ
Sbjct: 1458 KTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQI 1517
Query: 105 RQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQA--QAI 162
+ + +QI LE ++L +E L + Q+ L + + I
Sbjct: 1518 AENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKSEIDRKI 1577
Query: 163 AEHNAE--QLARELNCAREKVVHIF-RYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQ 219
AE + E QL R E + + S + E + + ++ N+ Q
Sbjct: 1578 AEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANR-Q 1636
Query: 220 TVHVLLH-NSLKPPEKPPERGGDE--KQMALLNQRISQLAENNISLKSEIERLKASVIRT 276
L H S++ K + D+ + L ++++ + L++E+E L+A++ +T
Sbjct: 1637 AAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQT 1696
Query: 277 EESALANEKRL---QEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAEL 333
E + E+ L E++ L T+ + L + + E + + +
Sbjct: 1697 ERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKA 1756
Query: 334 ERQLAASRAQVSTAEKER------EELKNRLHWQMKRLTENFEQA-QLRILGLQTQVQSL 386
++ + + +KE+ E +K L +K L ++A QL + G + Q+Q L
Sbjct: 1757 KKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKL 1816
Query: 387 R-RTASSTGDGDGENQECT 404
R + +GE ++ T
Sbjct: 1817 ETRIRELEFELEGEQKKNT 1835
>X13100-1|CAA31492.1| 1167|Homo sapiens myosin heavy chain (1167 AA)
protein.
Length = 1167
Score = 58.4 bits (135), Expect = 4e-08
Identities = 81/339 (23%), Positives = 148/339 (43%), Gaps = 37/339 (10%)
Query: 38 ATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQND---QLQDYRVKYL 94
+ T M + ++ F++ + A + R+ EE +L TL++E+ND Q+Q L
Sbjct: 70 SAETEKEMATMKEEFQKTKDELAKSEAKRKELEE--KLVTLVQEKNDLQLQVQAESENLL 127
Query: 95 QAQ----QLVEEQRRQXXXXXXXNTRIS--EQINLEIQRVKLKFQEKLQELAPIPDLLKA 148
A+ QL++ + + R E+IN E+ K K +++ EL D L+
Sbjct: 128 DAEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLEL 187
Query: 149 TQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQS 208
T +++ + A E+ + L EL+ E + + R +L L +DL
Sbjct: 188 TLAKVEKEKHA---TENKVKNLTEELSGLDETIAKLTREKKALQEAHQQAL--DDL---- 238
Query: 209 QSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIER 268
Q+E + N L ++ E E+ EK++ + L N L+ +++
Sbjct: 239 QAEEDKVNSLNKTKSKLEQQVEDLESSLEQ---EKKLRV------DLERNKRKLEGDLKL 289
Query: 269 LKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQT 328
+ S++ E ++RL++K E QL +++ DE + LQ + E LQ
Sbjct: 290 AQESILDLENDKQQLDERLKKKDFEYCQLQSKVE---DEQTLGLQFQKKIKE-----LQA 341
Query: 329 TVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTE 367
+ ELE ++ A RA + EK+R + L +RL E
Sbjct: 342 RIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEE 380
Score = 52.0 bits (119), Expect = 4e-06
Identities = 65/343 (18%), Positives = 140/343 (40%), Gaps = 17/343 (4%)
Query: 58 VRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRI 117
++ L+ E EEI+ R + Q DY A++L E R +T+I
Sbjct: 336 IKELQARIEELEEEIEAERATRAKTEKQRSDY------ARELEELSERLEEAGGVTSTQI 389
Query: 118 SEQINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEH--NAEQLARELN 175
++N + + LK + L+E + + AT +R K A + E N +++ ++L
Sbjct: 390 --ELNKKREAEFLKLRRDLEEATLQHEAMVAT-LRKKHADSVAELGEQIDNLQRVKQKLE 446
Query: 176 CAREKV-VHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIG--RGNKDQTVHVLLHNSLKPP 232
+ + + I S+ V+ E + + ++ RG ++ L + +
Sbjct: 447 KEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKS 506
Query: 233 EKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMH 292
E G +Q+ +SQL+ + + + E LK + ++ A LQ H
Sbjct: 507 RLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRH 566
Query: 293 ECAQLGGELDRTRD---EASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEK 349
+C L + + ++ E RAL +A+ + R +T + +L ++ +++ +
Sbjct: 567 DCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAQEKLAQRLQ 626
Query: 350 EREELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRRTASS 392
+ EE ++ + L + ++ Q + L V+ A++
Sbjct: 627 DSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAA 669
Score = 42.3 bits (95), Expect = 0.003
Identities = 80/397 (20%), Positives = 162/397 (40%), Gaps = 42/397 (10%)
Query: 27 LRELEMKFEGL-ATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQ 85
L E ++ E + AT S + EQ N++ +KQ + +E E + + + +
Sbjct: 406 LEEATLQHEAMVATLRKKHADSVAELGEQIDNLQRVKQ---KLEKEKSEFKLEIDDLSSS 462
Query: 86 LQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDL 145
++ +++ Q N I ++ E+ K + Q + EL+ +
Sbjct: 463 MESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLS-ELTTQKSRLQTEAGELSRQLEE 521
Query: 146 LKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYL-YSLYLVTTMTLTQEDL 204
++ +L ++QA ++ E N A+ + H + + L+ +++
Sbjct: 522 KESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEG 581
Query: 205 FGQSQSEIGRGNKD--------QTVHVLLHNSLKPP-EKPPERGGD-EKQMALLNQRISQ 254
+ Q + + N + +T + L+ EK +R D E+Q+ +N + +
Sbjct: 582 KAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAQEKLAQRLQDSEEQVEAVNAKCAS 641
Query: 255 LAENNISLKSEIERLKASVIRTEESALANEKR-------LQEKMHECAQLGGELDRTRDE 307
L + L+ E+E L V R A A +K+ L E +C + EL+ + E
Sbjct: 642 LEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKE 701
Query: 308 A----------SRALQRAHEQTETVR---KCLQTTVAELERQLAASRAQVSTAEKEREEL 354
+ A + A +Q ETV+ K L+ +A+L Q+A + + EK R+++
Sbjct: 702 SRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQI 761
Query: 355 ---KNRLHWQMKRLTENFEQAQLRILGLQ---TQVQS 385
K + ++ E + +IL +Q TQV+S
Sbjct: 762 ELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKS 798
Score = 36.3 bits (80), Expect = 0.20
Identities = 70/325 (21%), Positives = 132/325 (40%), Gaps = 33/325 (10%)
Query: 52 FEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXX 111
F+ E ++ + + + E EL ++ D+ + + + + + ++
Sbjct: 141 FQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATE 200
Query: 112 XXNTRISEQIN-LEIQRVKLKFQEK-LQEL-APIPDLLKATQMRLKDAQQAQAIAEHNAE 168
++E+++ L+ KL ++K LQE D L+A + ++ + ++ E E
Sbjct: 201 NKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVE 260
Query: 169 QLARELNCAREKVVHIFRYLYSLYLVTTMTLTQE---DLFGQSQSEIGRGNKDQTVHVLL 225
L L +EK + + L + L QE DL Q R K + L
Sbjct: 261 DLESSLE--QEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQL 318
Query: 226 HNSLKPPEKPPERGGDEKQMAL-LNQRISQLAENNISLKSEIERLKASVIRTEESALANE 284
+ ++ DE+ + L ++I +L L+ EIE +A+ +TE+
Sbjct: 319 QSKVE----------DEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYA 368
Query: 285 KRLQEKMHECAQLGG------ELDRTRD----EASRALQRA---HE-QTETVRKCLQTTV 330
+ L+E + GG EL++ R+ + R L+ A HE T+RK +V
Sbjct: 369 RELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVATLRKKHADSV 428
Query: 331 AELERQLAASRAQVSTAEKEREELK 355
AEL Q+ + EKE+ E K
Sbjct: 429 AELGEQIDNLQRVKQKLEKEKSEFK 453
Score = 34.7 bits (76), Expect = 0.60
Identities = 72/379 (18%), Positives = 148/379 (39%), Gaps = 23/379 (6%)
Query: 48 KEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVE---EQR 104
K + E + + A + R E+ +L+ +E DQL+ + + +Q + EQ
Sbjct: 685 KTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQI 744
Query: 105 RQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQA--QAI 162
+ + +QI LE ++L +E L + Q+ L + + I
Sbjct: 745 AENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKSEIDRKI 804
Query: 163 AEHNAE--QLARELNCAREKVVHIF-RYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQ 219
AE + E QL R E + + S + E + + ++ N+ Q
Sbjct: 805 AEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANR-Q 863
Query: 220 TVHVLLH-NSLKPPEKPPERGGDEKQMAL--LNQRISQLAENNISLKSEIERLKASVIRT 276
L H S++ K + D+ L ++++ + L++E+E L+A++ +T
Sbjct: 864 AAETLKHLRSVQGQLKDTQLHLDDALQTQEDLKEQLAIVERRANLLQAEVEELRATLEQT 923
Query: 277 EESALANEKRL---QEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAEL 333
E + E+ L E++ L T+ + L + + E + + +
Sbjct: 924 ERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKA 983
Query: 334 ERQLAASRAQVSTAEKER------EELKNRLHWQMKRLTENFEQA-QLRILGLQTQVQSL 386
++ + + +KE+ E +K L +K L ++A QL + G + Q+Q L
Sbjct: 984 KKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKL 1043
Query: 387 R-RTASSTGDGDGENQECT 404
R + +GE ++ T
Sbjct: 1044 ETRIRELEFELEGEQKKNT 1062
>BC126409-1|AAI26410.1| 1941|Homo sapiens myosin, heavy chain 2,
skeletal muscle, adult protein.
Length = 1941
Score = 56.4 bits (130), Expect = 2e-07
Identities = 79/339 (23%), Positives = 149/339 (43%), Gaps = 37/339 (10%)
Query: 38 ATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQND---QLQDYRVKYL 94
+ T M + ++ F++ + A + R+ EE ++ TL+KE+ND Q+Q
Sbjct: 848 SAETEKEMATMKEEFQKIKDELAKSEAKRKELEE--KMVTLLKEKNDLQLQVQAEAEGLA 905
Query: 95 QAQ----QLVEEQRRQXXXXXXXNTRIS--EQINLEIQRVKLKFQEKLQELAPIPDLLKA 148
A+ QL++ + + R E+IN E+ K K +++ EL D L+
Sbjct: 906 DAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLEL 965
Query: 149 TQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQS 208
T +++ + A E+ + L E+ E + + + +L TL +DL
Sbjct: 966 TLAKVEKEKHA---TENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTL--DDL---- 1016
Query: 209 QSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIER 268
Q+E + N + L + E E+ EK++ + +R + E ++ L E
Sbjct: 1017 QAEEDKVNTLTKAKIKLEQQVDDLEGSLEQ---EKKLRMDLERAKRKLEGDLKLAQE--- 1070
Query: 269 LKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQT 328
S++ E +++L++K E + L +++ DE + +Q + E LQ
Sbjct: 1071 ---SIMDIENEKQQLDEKLKKKEFEISNLQSKIE---DEQALGIQLQKKIKE-----LQA 1119
Query: 329 TVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTE 367
+ ELE ++ A RA + AEK+R +L L +RL E
Sbjct: 1120 RIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEE 1158
Score = 42.3 bits (95), Expect = 0.003
Identities = 85/399 (21%), Positives = 165/399 (41%), Gaps = 48/399 (12%)
Query: 22 ETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKE 81
ET +L + + L T + + E++ +Q + LK+ + ++EI +L + E
Sbjct: 1468 ETHAELEASQKEARSLGTELFKIKNAYEESLDQ---LETLKRENKNLQQEISDLTEQIAE 1524
Query: 82 QNDQLQDY-RVKYLQAQQLVEEQRRQXXXXXXXNTRISE--QINLEIQRVKLKFQEKLQE 138
++ + ++K Q+ E Q + +I LE+ +VK + K+ E
Sbjct: 1525 GGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAE 1584
Query: 139 LAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMT 198
D LK +R+ ++ Q+ AE + A L E ++ L M
Sbjct: 1585 KDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEI--QLNHANRMA 1642
Query: 199 LTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAEN 258
+ +Q + KD +H L ++L+ E E Q+A++ +R + L
Sbjct: 1643 AEALRNYRNTQGIL----KDTQIH--LDDALRSQEDLKE------QLAMVERRANLL--- 1687
Query: 259 NISLKSEIERLKASVIRTEESALANEKRLQEK--------------MHECAQLGGELDRT 304
++EIE L+A++ +TE S E+ L + ++ +L ++ +
Sbjct: 1688 ----QAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQM 1743
Query: 305 RDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKR 364
+ E LQ A E +K + T A + +L + Q ++A ER +K + +K
Sbjct: 1744 QGEMEDILQEARNAEEKAKKAI-TDAAMMAEEL--KKEQDTSAHLER--MKKNMEQTVKD 1798
Query: 365 LTENFEQA-QLRILGLQTQVQSLR-RTASSTGDGDGENQ 401
L ++A QL + G + Q+Q L R G+ + E +
Sbjct: 1799 LQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQK 1837
Score = 39.1 bits (87), Expect = 0.028
Identities = 59/332 (17%), Positives = 134/332 (40%), Gaps = 15/332 (4%)
Query: 67 EAREEIDELRTLMKEQNDQLQDYRVKYLQAQQ----LVEEQRRQXXXXXXXNTRISEQIN 122
+ +++I EL+ ++E ++++ R +A++ L E S QI
Sbjct: 1109 QLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIE 1168
Query: 123 LEIQRVKLKFQEKLQEL--APIPDLLKATQMRLKDAQQAQAIAEH--NAEQLARELNCAR 178
+ +R + +FQ+ ++L A + A +R K A + E N +++ ++L +
Sbjct: 1169 MNKKR-EAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEK 1227
Query: 179 EKV-VHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEK--P 235
++ + I ++ V+ E + + ++ + L N L
Sbjct: 1228 SEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQ 1287
Query: 236 PERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECA 295
E G +Q+ +SQL+ + +IE LK + ++ A LQ H+C
Sbjct: 1288 TESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCD 1347
Query: 296 QLGGELDRTRD---EASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKERE 352
L + + ++ E RAL +A+ + R +T + +L ++ +++ + E
Sbjct: 1348 LLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAE 1407
Query: 353 ELKNRLHWQMKRLTENFEQAQLRILGLQTQVQ 384
E ++ + L + ++ Q + L V+
Sbjct: 1408 EHVEAVNAKCASLEKTKQRLQNEVEDLMLDVE 1439
Score = 37.1 bits (82), Expect = 0.11
Identities = 35/130 (26%), Positives = 61/130 (46%), Gaps = 15/130 (11%)
Query: 241 DEKQMAL-LNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGG 299
DE+ + + L ++I +L L+ EIE +AS + E+ + L+E + GG
Sbjct: 1102 DEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGG 1161
Query: 300 ------ELDRTRDEASRALQR-------AHEQTE-TVRKCLQTTVAELERQLAASRAQVS 345
E+++ R+ + ++R HE T T+RK +VAEL Q+ +
Sbjct: 1162 ATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQ 1221
Query: 346 TAEKEREELK 355
EKE+ E+K
Sbjct: 1222 KLEKEKSEMK 1231
Score = 37.1 bits (82), Expect = 0.11
Identities = 70/356 (19%), Positives = 144/356 (40%), Gaps = 26/356 (7%)
Query: 61 LKQCYREAREEIDELRTLMKEQNDQLQDYRVKY----LQAQQLVEEQRRQXXXXXXXNTR 116
L++ Y E +E EL+ + + N ++ +R KY +Q + +EE +++
Sbjct: 1349 LREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEE 1408
Query: 117 ISEQINLE---IQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQ--AQAIAE--HNAEQ 169
E +N + +++ K + Q ++++L + A L Q+ + +AE E+
Sbjct: 1409 HVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEE 1468
Query: 170 LARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVL----- 224
EL ++++ + L+ + +L Q + + + + D T +
Sbjct: 1469 THAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKR 1528
Query: 225 LHNSLKPPEKPPERGGDEKQMALLNQRISQLAENN--ISLKSEIERLKASV---IRTEES 279
+H L+ +K E+ E Q AL S E + ++ E+ ++K+ V I ++
Sbjct: 1529 IH-ELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDE 1587
Query: 280 ALANEKRLQEKMHECAQ--LGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQL 337
+ KR ++ E Q L E+ R+R++A R ++ + L L
Sbjct: 1588 EIDQLKRNHIRIVESMQSTLDAEI-RSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEAL 1646
Query: 338 AASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRRTASST 393
R + + L + L Q + L E + R LQ +++ LR T T
Sbjct: 1647 RNYRNTQGILKDTQIHLDDALRSQ-EDLKEQLAMVERRANLLQAEIEELRATLEQT 1701
>AF111784-1|AAD29950.1| 1941|Homo sapiens myosin heavy chain IIa
protein.
Length = 1941
Score = 56.4 bits (130), Expect = 2e-07
Identities = 79/339 (23%), Positives = 149/339 (43%), Gaps = 37/339 (10%)
Query: 38 ATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQND---QLQDYRVKYL 94
+ T M + ++ F++ + A + R+ EE ++ TL+KE+ND Q+Q
Sbjct: 848 SAETEKEMATMKEEFQKIKDELAKSEAKRKELEE--KMVTLLKEKNDLQLQVQAEAEGLA 905
Query: 95 QAQ----QLVEEQRRQXXXXXXXNTRIS--EQINLEIQRVKLKFQEKLQELAPIPDLLKA 148
A+ QL++ + + R E+IN E+ K K +++ EL D L+
Sbjct: 906 DAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLEL 965
Query: 149 TQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQS 208
T +++ + A E+ + L E+ E + + + +L TL +DL
Sbjct: 966 TLAKVEKEKHA---TENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTL--DDL---- 1016
Query: 209 QSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIER 268
Q+E + N + L + E E+ EK++ + +R + E ++ L E
Sbjct: 1017 QAEEDKVNTLTKAKIKLEQQVDDLEGSLEQ---EKKLRMDLERAKRKLEGDLKLAQE--- 1070
Query: 269 LKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQT 328
S++ E +++L++K E + L +++ DE + +Q + E LQ
Sbjct: 1071 ---SIMDIENEKQQLDEKLKKKEFEISNLQSKIE---DEQALGIQLQKKIKE-----LQA 1119
Query: 329 TVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTE 367
+ ELE ++ A RA + AEK+R +L L +RL E
Sbjct: 1120 RIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEE 1158
Score = 42.3 bits (95), Expect = 0.003
Identities = 85/399 (21%), Positives = 165/399 (41%), Gaps = 48/399 (12%)
Query: 22 ETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKE 81
ET +L + + L T + + E++ +Q + LK+ + ++EI +L + E
Sbjct: 1468 ETHAELEASQKEARSLGTELFKIKNAYEESLDQ---LETLKRENKNLQQEISDLTEQIAE 1524
Query: 82 QNDQLQDY-RVKYLQAQQLVEEQRRQXXXXXXXNTRISE--QINLEIQRVKLKFQEKLQE 138
++ + ++K Q+ E Q + +I LE+ +VK + K+ E
Sbjct: 1525 GGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAE 1584
Query: 139 LAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMT 198
D LK +R+ ++ Q+ AE + A L E ++ L M
Sbjct: 1585 KDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEI--QLNHANRMA 1642
Query: 199 LTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAEN 258
+ +Q + KD +H L ++L+ E E Q+A++ +R + L
Sbjct: 1643 AEALRNYRNTQGIL----KDTQIH--LDDALRSQEDLKE------QLAMVERRANLL--- 1687
Query: 259 NISLKSEIERLKASVIRTEESALANEKRLQEK--------------MHECAQLGGELDRT 304
++EIE L+A++ +TE S E+ L + ++ +L ++ +
Sbjct: 1688 ----QAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQM 1743
Query: 305 RDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKR 364
+ E LQ A E +K + T A + +L + Q ++A ER +K + +K
Sbjct: 1744 QGEMEDILQEARNAEEKAKKAI-TDAAMMAEEL--KKEQDTSAHLER--MKKNMEQTVKD 1798
Query: 365 LTENFEQA-QLRILGLQTQVQSLR-RTASSTGDGDGENQ 401
L ++A QL + G + Q+Q L R G+ + E +
Sbjct: 1799 LQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQK 1837
Score = 39.1 bits (87), Expect = 0.028
Identities = 59/332 (17%), Positives = 134/332 (40%), Gaps = 15/332 (4%)
Query: 67 EAREEIDELRTLMKEQNDQLQDYRVKYLQAQQ----LVEEQRRQXXXXXXXNTRISEQIN 122
+ +++I EL+ ++E ++++ R +A++ L E S QI
Sbjct: 1109 QLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIE 1168
Query: 123 LEIQRVKLKFQEKLQEL--APIPDLLKATQMRLKDAQQAQAIAEH--NAEQLARELNCAR 178
+ +R + +FQ+ ++L A + A +R K A + E N +++ ++L +
Sbjct: 1169 MNKKR-EAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEK 1227
Query: 179 EKV-VHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEK--P 235
++ + I ++ V+ E + + ++ + L N L
Sbjct: 1228 SEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQ 1287
Query: 236 PERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECA 295
E G +Q+ +SQL+ + +IE LK + ++ A LQ H+C
Sbjct: 1288 TESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCD 1347
Query: 296 QLGGELDRTRD---EASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKERE 352
L + + ++ E RAL +A+ + R +T + +L ++ +++ + E
Sbjct: 1348 LLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAE 1407
Query: 353 ELKNRLHWQMKRLTENFEQAQLRILGLQTQVQ 384
E ++ + L + ++ Q + L V+
Sbjct: 1408 EHVEAVNAKCASLEKTKQRLQNEVEDLMLDVE 1439
Score = 37.1 bits (82), Expect = 0.11
Identities = 35/130 (26%), Positives = 61/130 (46%), Gaps = 15/130 (11%)
Query: 241 DEKQMAL-LNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGG 299
DE+ + + L ++I +L L+ EIE +AS + E+ + L+E + GG
Sbjct: 1102 DEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGG 1161
Query: 300 ------ELDRTRDEASRALQR-------AHEQTE-TVRKCLQTTVAELERQLAASRAQVS 345
E+++ R+ + ++R HE T T+RK +VAEL Q+ +
Sbjct: 1162 ATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQ 1221
Query: 346 TAEKEREELK 355
EKE+ E+K
Sbjct: 1222 KLEKEKSEMK 1231
Score = 37.1 bits (82), Expect = 0.11
Identities = 70/356 (19%), Positives = 144/356 (40%), Gaps = 26/356 (7%)
Query: 61 LKQCYREAREEIDELRTLMKEQNDQLQDYRVKY----LQAQQLVEEQRRQXXXXXXXNTR 116
L++ Y E +E EL+ + + N ++ +R KY +Q + +EE +++
Sbjct: 1349 LREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEE 1408
Query: 117 ISEQINLE---IQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQ--AQAIAE--HNAEQ 169
E +N + +++ K + Q ++++L + A L Q+ + +AE E+
Sbjct: 1409 HVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEE 1468
Query: 170 LARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVL----- 224
EL ++++ + L+ + +L Q + + + + D T +
Sbjct: 1469 THAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKR 1528
Query: 225 LHNSLKPPEKPPERGGDEKQMALLNQRISQLAENN--ISLKSEIERLKASV---IRTEES 279
+H L+ +K E+ E Q AL S E + ++ E+ ++K+ V I ++
Sbjct: 1529 IH-ELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDE 1587
Query: 280 ALANEKRLQEKMHECAQ--LGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQL 337
+ KR ++ E Q L E+ R+R++A R ++ + L L
Sbjct: 1588 EIDQLKRNHIRIVESMQSTLDAEI-RSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEAL 1646
Query: 338 AASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRRTASST 393
R + + L + L Q + L E + R LQ +++ LR T T
Sbjct: 1647 RNYRNTQGILKDTQIHLDDALRSQ-EDLKEQLAMVERRANLLQAEIEELRATLEQT 1701
>X51593-1|CAA35942.1| 1085|Homo sapiens embryonic myosin heavy chain
(1085 AA) protein.
Length = 1085
Score = 56.0 bits (129), Expect = 2e-07
Identities = 77/309 (24%), Positives = 137/309 (44%), Gaps = 36/309 (11%)
Query: 69 REEIDE-LRTLMKEQND---QLQDYRVKYLQAQ----QLVEEQRRQXXXXXXXNTRIS-- 118
R+E++E L TL++E+ND Q+Q L A+ QL++ + + R
Sbjct: 16 RKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQLIKAKFQLEAKIKEVTERAEDE 75
Query: 119 EQINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAR 178
E+IN E+ K K +++ EL D L+ T +++ + A E+ + L EL+
Sbjct: 76 EEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHA---TENKVKNLTEELSGLD 132
Query: 179 EKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPER 238
E + + R +L L +DL Q+E + N L ++ E E+
Sbjct: 133 ETIAKLTREKKALQEAHQQAL--DDL----QAEEDKVNSLNKTKSKLEQQVEDLESSLEQ 186
Query: 239 GGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLG 298
EK++ + L N L+ +++ + S++ E ++RL++K E QL
Sbjct: 187 ---EKKLRV------DLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQ 237
Query: 299 GELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRL 358
+++ DE + LQ + E LQ + ELE ++ A RA + EK+R + L
Sbjct: 238 SKVE---DEQTLGLQFQKKIKE-----LQARIEELEEEIEAERATRAKTEKQRSDYAREL 289
Query: 359 HWQMKRLTE 367
+RL E
Sbjct: 290 EELSERLEE 298
Score = 52.0 bits (119), Expect = 4e-06
Identities = 65/343 (18%), Positives = 140/343 (40%), Gaps = 17/343 (4%)
Query: 58 VRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRI 117
++ L+ E EEI+ R + Q DY A++L E R +T+I
Sbjct: 254 IKELQARIEELEEEIEAERATRAKTEKQRSDY------ARELEELSERLEEAGGVTSTQI 307
Query: 118 SEQINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEH--NAEQLARELN 175
++N + + LK + L+E + + AT +R K A + E N +++ ++L
Sbjct: 308 --ELNKKREAEFLKLRRDLEEATLQHEAMVAT-LRKKHADSVAELGEQIDNLQRVKQKLE 364
Query: 176 CAREKV-VHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIG--RGNKDQTVHVLLHNSLKPP 232
+ + + I S+ V+ E + + ++ RG ++ L + +
Sbjct: 365 KEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKS 424
Query: 233 EKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMH 292
E G +Q+ +SQL+ + + + E LK + ++ A LQ H
Sbjct: 425 RLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALGHALQSSRH 484
Query: 293 ECAQLGGELDRTRD---EASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEK 349
+C L + + ++ E RAL +A+ + R +T + +L ++ +++ +
Sbjct: 485 DCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQ 544
Query: 350 EREELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRRTASS 392
+ EE ++ + L + ++ Q + L V+ A++
Sbjct: 545 DSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAA 587
Score = 40.3 bits (90), Expect = 0.012
Identities = 43/170 (25%), Positives = 77/170 (45%), Gaps = 26/170 (15%)
Query: 242 EKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKR-------LQEKMHEC 294
E+Q+ +N + + L + L+ E+E L V R A A +K+ L E +C
Sbjct: 547 EEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWKTKC 606
Query: 295 AQLGGELDRTRDEA----------SRALQRAHEQTETVR---KCLQTTVAELERQLAASR 341
+ EL+ + E+ A + A +Q ETV+ K L+ +A+L Q+A +
Sbjct: 607 EESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENG 666
Query: 342 AQVSTAEKEREEL---KNRLHWQMKRLTENFEQAQLRILGLQ---TQVQS 385
+ EK R+++ K + ++ E + +IL +Q TQV+S
Sbjct: 667 KTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKS 716
Score = 36.3 bits (80), Expect = 0.20
Identities = 70/325 (21%), Positives = 132/325 (40%), Gaps = 33/325 (10%)
Query: 52 FEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXX 111
F+ E ++ + + + E EL ++ D+ + + + + + ++
Sbjct: 59 FQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATE 118
Query: 112 XXNTRISEQIN-LEIQRVKLKFQEK-LQEL-APIPDLLKATQMRLKDAQQAQAIAEHNAE 168
++E+++ L+ KL ++K LQE D L+A + ++ + ++ E E
Sbjct: 119 NKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVE 178
Query: 169 QLARELNCAREKVVHIFRYLYSLYLVTTMTLTQE---DLFGQSQSEIGRGNKDQTVHVLL 225
L L +EK + + L + L QE DL Q R K + L
Sbjct: 179 DLESSLE--QEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQL 236
Query: 226 HNSLKPPEKPPERGGDEKQMAL-LNQRISQLAENNISLKSEIERLKASVIRTEESALANE 284
+ ++ DE+ + L ++I +L L+ EIE +A+ +TE+
Sbjct: 237 QSKVE----------DEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYA 286
Query: 285 KRLQEKMHECAQLGG------ELDRTRD----EASRALQRA---HE-QTETVRKCLQTTV 330
+ L+E + GG EL++ R+ + R L+ A HE T+RK +V
Sbjct: 287 RELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVATLRKKHADSV 346
Query: 331 AELERQLAASRAQVSTAEKEREELK 355
AEL Q+ + EKE+ E K
Sbjct: 347 AELGEQIDNLQRVKQKLEKEKSEFK 371
Score = 33.5 bits (73), Expect = 1.4
Identities = 82/398 (20%), Positives = 155/398 (38%), Gaps = 40/398 (10%)
Query: 22 ETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRA----LKQCYREAREEIDELRT 77
E+Q +L + L+T L + E+A +Q V+ L+Q + E+I E
Sbjct: 608 ESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGK 667
Query: 78 LMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQ 137
+ E + ++ Q +EE RI LE+ +VK + K+
Sbjct: 668 TIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQ----LELTQVKSEIDRKIA 723
Query: 138 ELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTM 197
E + LK R + Q+ AE A L E ++ S +
Sbjct: 724 EKDEEIEQLKRNYQRTVETMQSALDAEVRRANEAIRLKKKMEGDLNEIEIQLS-HANRQA 782
Query: 198 TLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAE 257
T + L Q ++ KD +H L ++L+ E E Q+A++ +R + L
Sbjct: 783 AETLKHL-RSVQGQL----KDTQLH--LDDALRGQEDLKE------QLAIVERRANLL-- 827
Query: 258 NNISLKSEIERLKASVIRTEESALANEKRL---QEKMHECAQLGGELDRTRDEASRALQR 314
++E+E L+A++ +TE + E+ L E++ L T+ + L +
Sbjct: 828 -----QAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQ 882
Query: 315 AHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKER------EELKNRLHWQMKRLTEN 368
+ E + + + ++ + + +KE+ E +K L +K L
Sbjct: 883 LQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHR 942
Query: 369 FEQA-QLRILGLQTQVQSLR-RTASSTGDGDGENQECT 404
++A QL + G + Q+Q L R + +GE ++ T
Sbjct: 943 LDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNT 980
>X15696-1|CAA33731.1| 1085|Homo sapiens protein ( Human muscle mRNA
for embryonic myosin heavy chain (SMHCE). ).
Length = 1085
Score = 56.0 bits (129), Expect = 2e-07
Identities = 77/309 (24%), Positives = 137/309 (44%), Gaps = 36/309 (11%)
Query: 69 REEIDE-LRTLMKEQND---QLQDYRVKYLQAQ----QLVEEQRRQXXXXXXXNTRIS-- 118
R+E++E L TL++E+ND Q+Q L A+ QL++ + + R
Sbjct: 16 RKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQLIKAKFQLEAKIKEVTERAEDE 75
Query: 119 EQINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAR 178
E+IN E+ K K +++ EL D L+ T +++ + A E+ + L EL+
Sbjct: 76 EEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHA---TENKVKNLTEELSGLD 132
Query: 179 EKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPER 238
E + + R +L L +DL Q+E + N L ++ E E+
Sbjct: 133 ETIAKLTREKKALQEAHQQAL--DDL----QAEEDKVNSLNKTKSKLEQQVEDLESSLEQ 186
Query: 239 GGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLG 298
EK++ + L N L+ +++ + S++ E ++RL++K E QL
Sbjct: 187 ---EKKLRV------DLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQ 237
Query: 299 GELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRL 358
+++ DE + LQ + E LQ + ELE ++ A RA + EK+R + L
Sbjct: 238 SKVE---DEQTLGLQFQKKIKE-----LQARIEELEEEIEAERATRAKTEKQRSDYAREL 289
Query: 359 HWQMKRLTE 367
+RL E
Sbjct: 290 EELSERLEE 298
Score = 52.4 bits (120), Expect = 3e-06
Identities = 65/343 (18%), Positives = 140/343 (40%), Gaps = 17/343 (4%)
Query: 58 VRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRI 117
++ L+ E EEI+ R + Q DY A++L E R +T+I
Sbjct: 254 IKELQARIEELEEEIEAERATRAKTEKQRSDY------ARELEELSERLEEAGGVTSTQI 307
Query: 118 SEQINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEH--NAEQLARELN 175
++N + + LK + L+E + + AT +R K A + E N +++ ++L
Sbjct: 308 --ELNKKREAEFLKLRRDLEEATLQHEAMVAT-LRKKHADSVAELGEQIDNLQRVKQKLE 364
Query: 176 CAREKV-VHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIG--RGNKDQTVHVLLHNSLKPP 232
+ + + I S+ V+ E + + ++ RG ++ L + +
Sbjct: 365 KEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKS 424
Query: 233 EKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMH 292
E G +Q+ +SQL+ + + + E LK + ++ A LQ H
Sbjct: 425 RLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRH 484
Query: 293 ECAQLGGELDRTRD---EASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEK 349
+C L + + ++ E RAL +A+ + R +T + +L ++ +++ +
Sbjct: 485 DCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQ 544
Query: 350 EREELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRRTASS 392
+ EE ++ + L + ++ Q + L V+ A++
Sbjct: 545 DSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAA 587
Score = 41.5 bits (93), Expect = 0.005
Identities = 79/397 (19%), Positives = 162/397 (40%), Gaps = 42/397 (10%)
Query: 27 LRELEMKFEGL-ATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQ 85
L E ++ E + AT S + EQ N++ +KQ + +E E + + + +
Sbjct: 324 LEEATLQHEAMVATLRKKHADSVAELGEQIDNLQRVKQ---KLEKEKSEFKLEIDDLSSS 380
Query: 86 LQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDL 145
++ +++ Q N I ++ E+ K + Q + EL+ +
Sbjct: 381 MESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLS-ELTTQKSRLQTEAGELSRQLEE 439
Query: 146 LKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYL-YSLYLVTTMTLTQEDL 204
++ +L ++QA ++ E N A+ + H + + L+ +++
Sbjct: 440 KESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEG 499
Query: 205 FGQSQSEIGRGNKD--------QTVHVLLHNSLKPPEKP-PERGGD-EKQMALLNQRISQ 254
+ Q + + N + +T + L+ +K +R D E+Q+ +N + +
Sbjct: 500 KAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCAS 559
Query: 255 LAENNISLKSEIERLKASVIRTEESALANEKR-------LQEKMHECAQLGGELDRTRDE 307
L + L+ E+E L V R A A +K+ L E +C + EL+ + E
Sbjct: 560 LEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKE 619
Query: 308 A----------SRALQRAHEQTETVR---KCLQTTVAELERQLAASRAQVSTAEKEREEL 354
+ A + A +Q ETV+ K L+ +A+L Q+A + + EK R+++
Sbjct: 620 SRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQI 679
Query: 355 ---KNRLHWQMKRLTENFEQAQLRILGLQ---TQVQS 385
K + ++ E + +IL +Q TQV+S
Sbjct: 680 ELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKS 716
Score = 36.3 bits (80), Expect = 0.20
Identities = 70/325 (21%), Positives = 132/325 (40%), Gaps = 33/325 (10%)
Query: 52 FEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXX 111
F+ E ++ + + + E EL ++ D+ + + + + + ++
Sbjct: 59 FQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATE 118
Query: 112 XXNTRISEQIN-LEIQRVKLKFQEK-LQEL-APIPDLLKATQMRLKDAQQAQAIAEHNAE 168
++E+++ L+ KL ++K LQE D L+A + ++ + ++ E E
Sbjct: 119 NKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVE 178
Query: 169 QLARELNCAREKVVHIFRYLYSLYLVTTMTLTQE---DLFGQSQSEIGRGNKDQTVHVLL 225
L L +EK + + L + L QE DL Q R K + L
Sbjct: 179 DLESSLE--QEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQL 236
Query: 226 HNSLKPPEKPPERGGDEKQMAL-LNQRISQLAENNISLKSEIERLKASVIRTEESALANE 284
+ ++ DE+ + L ++I +L L+ EIE +A+ +TE+
Sbjct: 237 QSKVE----------DEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYA 286
Query: 285 KRLQEKMHECAQLGG------ELDRTRD----EASRALQRA---HE-QTETVRKCLQTTV 330
+ L+E + GG EL++ R+ + R L+ A HE T+RK +V
Sbjct: 287 RELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVATLRKKHADSV 346
Query: 331 AELERQLAASRAQVSTAEKEREELK 355
AEL Q+ + EKE+ E K
Sbjct: 347 AELGEQIDNLQRVKQKLEKEKSEFK 371
Score = 34.7 bits (76), Expect = 0.60
Identities = 72/379 (18%), Positives = 149/379 (39%), Gaps = 23/379 (6%)
Query: 48 KEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVE---EQR 104
K + E + + A + R E+ +L+ +E DQL+ + + +Q + EQ
Sbjct: 603 KTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQI 662
Query: 105 RQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQA--QAI 162
+ + +QI LE ++L +E L + Q+ L + + I
Sbjct: 663 AENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKSEIDRKI 722
Query: 163 AEHNAE--QLARELNCAREKVVHIF-RYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQ 219
AE + E QL R E + + S + E + + ++ N+ Q
Sbjct: 723 AEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANR-Q 781
Query: 220 TVHVLLH-NSLKPPEKPPERGGDE--KQMALLNQRISQLAENNISLKSEIERLKASVIRT 276
L H S++ K + D+ + L ++++ + L++E+E L+A++ +T
Sbjct: 782 AAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQT 841
Query: 277 EESALANEKRL---QEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAEL 333
E + E+ L E++ L T+ + L + + E + + +
Sbjct: 842 ERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKA 901
Query: 334 ERQLAASRAQVSTAEKER------EELKNRLHWQMKRLTENFEQA-QLRILGLQTQVQSL 386
++ + + +KE+ E +K L +K L ++A QL + G + Q+Q L
Sbjct: 902 KKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKL 961
Query: 387 R-RTASSTGDGDGENQECT 404
R + +GE ++ T
Sbjct: 962 ETRIRELEFELEGEQKKNT 980
>M69181-1|AAA99177.1| 1976|Homo sapiens non-muscle myosin B protein.
Length = 1976
Score = 56.0 bits (129), Expect = 2e-07
Identities = 78/377 (20%), Positives = 162/377 (42%), Gaps = 27/377 (7%)
Query: 29 ELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQ- 87
E E + + L LM SK+ + NV L++ R ++++E+RT ++E D+LQ
Sbjct: 1501 EFERQNKQLRADMEDLMSSKDDVGK---NVHELEKSKRALEQQVEEMRTQLEELEDELQA 1557
Query: 88 --DYRVKYLQAQQLVEEQ-RRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPD 144
D +++ Q ++ Q R N + +++ ++ + +++ ++ A
Sbjct: 1558 TEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVA 1617
Query: 145 LLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDL 204
K ++ LKD + A +++ ++L + ++ R L +++++
Sbjct: 1618 SKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQREL------EEARASRDEI 1671
Query: 205 FGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKS 264
F QS+ + + + L L E+ R E++ L I+ A +L
Sbjct: 1672 FAQSKESEKKLKSLEAEILQLQEELASSER--ARRHAEQERDELADEITNSASGKSALLD 1729
Query: 265 EIERLKASVIRTE---ESALANEKRLQEKMHECA----QLGGELDRTRDEASRALQRAHE 317
E RL+A + + E E +N + L ++ + L EL R A ++ A +
Sbjct: 1730 EKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKS-DNARQ 1788
Query: 318 QTETVRKCLQTTVAELERQLAAS-RAQVSTAEKEREELKNRLHWQMK-RLTEN--FEQAQ 373
Q E K L+ + ELE + + +A +S E + +L+ +L + K R N + +
Sbjct: 1789 QLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTE 1848
Query: 374 LRILGLQTQVQSLRRTA 390
++ + QV+ RR A
Sbjct: 1849 KKLKEIFMQVEDERRHA 1865
Score = 38.3 bits (85), Expect = 0.049
Identities = 69/336 (20%), Positives = 139/336 (41%), Gaps = 35/336 (10%)
Query: 27 LRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQND-- 84
L ++ + E L L+ KE+ + E + +++ +++ EE + L ++ + +
Sbjct: 844 LLQVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELF 903
Query: 85 -QLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIP 143
+ ++ R + +Q +EE E+ N +Q K K Q +Q+L
Sbjct: 904 AEAEEMRARLAAKKQELEE----ILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQL 959
Query: 144 DLLKATQMRLK-DAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQE 202
D + + +L+ + A+A + E++ L K + + + + L +E
Sbjct: 960 DEEEGARQKLQLEKVTAEAKIKKMEEEILL-LEDQNSKFIKEKKLMEDRIAECSSQLAEE 1018
Query: 203 DLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISL 262
+ ++ ++I NK + + L LK EK R EK L+ + L + L
Sbjct: 1019 EEKAKNLAKIR--NKQEVMISDLEERLKKEEKT--RQELEKAKRKLDGETTDLQDQIAEL 1074
Query: 263 KSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETV 322
+++I+ LK + + EE +L G L R DE + + V
Sbjct: 1075 QAQIDELKLQLAKKEE-----------------ELQGALARGDDETLHK----NNALKVV 1113
Query: 323 RKCLQTTVAELERQLAASRAQVSTAEKEREELKNRL 358
R+ LQ +AEL+ + +A + AEK++ +L L
Sbjct: 1114 RE-LQAQIAELQEDFESEKASRNKAEKQKRDLSEEL 1148
>BC117691-1|AAI17692.1| 1976|Homo sapiens myosin, heavy chain 10,
non-muscle protein.
Length = 1976
Score = 56.0 bits (129), Expect = 2e-07
Identities = 78/377 (20%), Positives = 162/377 (42%), Gaps = 27/377 (7%)
Query: 29 ELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQ- 87
E E + + L LM SK+ + NV L++ R ++++E+RT ++E D+LQ
Sbjct: 1501 EFERQNKQLRADMEDLMSSKDDVGK---NVHELEKSKRALEQQVEEMRTQLEELEDELQA 1557
Query: 88 --DYRVKYLQAQQLVEEQ-RRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPD 144
D +++ Q ++ Q R N + +++ ++ + +++ ++ A
Sbjct: 1558 TEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVA 1617
Query: 145 LLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDL 204
K ++ LKD + A +++ ++L + ++ R L +++++
Sbjct: 1618 SKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQREL------EEARASRDEI 1671
Query: 205 FGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKS 264
F QS+ + + + L L E+ R E++ L I+ A +L
Sbjct: 1672 FAQSKESEKKLKSLEAEILQLQEELASSER--ARRHAEQERDELADEITNSASGKSALLD 1729
Query: 265 EIERLKASVIRTE---ESALANEKRLQEKMHECA----QLGGELDRTRDEASRALQRAHE 317
E RL+A + + E E +N + L ++ + L EL R A ++ A +
Sbjct: 1730 EKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKS-DNARQ 1788
Query: 318 QTETVRKCLQTTVAELERQLAAS-RAQVSTAEKEREELKNRLHWQMK-RLTEN--FEQAQ 373
Q E K L+ + ELE + + +A +S E + +L+ +L + K R N + +
Sbjct: 1789 QLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTE 1848
Query: 374 LRILGLQTQVQSLRRTA 390
++ + QV+ RR A
Sbjct: 1849 KKLKEIFMQVEDERRHA 1865
Score = 38.3 bits (85), Expect = 0.049
Identities = 69/336 (20%), Positives = 139/336 (41%), Gaps = 35/336 (10%)
Query: 27 LRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQND-- 84
L ++ + E L L+ KE+ + E + +++ +++ EE + L ++ + +
Sbjct: 844 LLQVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELF 903
Query: 85 -QLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIP 143
+ ++ R + +Q +EE E+ N +Q K K Q +Q+L
Sbjct: 904 AEAEEMRARLAAKKQELEE----ILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQL 959
Query: 144 DLLKATQMRLK-DAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQE 202
D + + +L+ + A+A + E++ L K + + + + L +E
Sbjct: 960 DEEEGARQKLQLEKVTAEAKIKKMEEEILL-LEDQNSKFIKEKKLMEDRIAECSSQLAEE 1018
Query: 203 DLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISL 262
+ ++ ++I NK + + L LK EK R EK L+ + L + L
Sbjct: 1019 EEKAKNLAKIR--NKQEVMISDLEERLKKEEKT--RQELEKAKRKLDGETTDLQDQIAEL 1074
Query: 263 KSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETV 322
+++I+ LK + + EE +L G L R DE + + V
Sbjct: 1075 QAQIDELKLQLAKKEE-----------------ELQGALARGDDETLHK----NNALKVV 1113
Query: 323 RKCLQTTVAELERQLAASRAQVSTAEKEREELKNRL 358
R+ LQ +AEL+ + +A + AEK++ +L L
Sbjct: 1114 RE-LQAQIAELQEDFESEKASRNKAEKQKRDLSEEL 1148
>BC117690-1|AAI17691.1| 1976|Homo sapiens myosin, heavy chain 10,
non-muscle protein.
Length = 1976
Score = 56.0 bits (129), Expect = 2e-07
Identities = 78/377 (20%), Positives = 162/377 (42%), Gaps = 27/377 (7%)
Query: 29 ELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQ- 87
E E + + L LM SK+ + NV L++ R ++++E+RT ++E D+LQ
Sbjct: 1501 EFERQNKQLRADMEDLMSSKDDVGK---NVHELEKSKRALEQQVEEMRTQLEELEDELQA 1557
Query: 88 --DYRVKYLQAQQLVEEQ-RRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPD 144
D +++ Q ++ Q R N + +++ ++ + +++ ++ A
Sbjct: 1558 TEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVA 1617
Query: 145 LLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDL 204
K ++ LKD + A +++ ++L + ++ R L +++++
Sbjct: 1618 SKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQREL------EEARASRDEI 1671
Query: 205 FGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKS 264
F QS+ + + + L L E+ R E++ L I+ A +L
Sbjct: 1672 FAQSKESEKKLKSLEAEILQLQEELASSER--ARRHAEQERDELADEITNSASGKSALLD 1729
Query: 265 EIERLKASVIRTE---ESALANEKRLQEKMHECA----QLGGELDRTRDEASRALQRAHE 317
E RL+A + + E E +N + L ++ + L EL R A ++ A +
Sbjct: 1730 EKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKS-DNARQ 1788
Query: 318 QTETVRKCLQTTVAELERQLAAS-RAQVSTAEKEREELKNRLHWQMK-RLTEN--FEQAQ 373
Q E K L+ + ELE + + +A +S E + +L+ +L + K R N + +
Sbjct: 1789 QLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTE 1848
Query: 374 LRILGLQTQVQSLRRTA 390
++ + QV+ RR A
Sbjct: 1849 KKLKEIFMQVEDERRHA 1865
Score = 38.3 bits (85), Expect = 0.049
Identities = 69/336 (20%), Positives = 139/336 (41%), Gaps = 35/336 (10%)
Query: 27 LRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQND-- 84
L ++ + E L L+ KE+ + E + +++ +++ EE + L ++ + +
Sbjct: 844 LLQVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELF 903
Query: 85 -QLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIP 143
+ ++ R + +Q +EE E+ N +Q K K Q +Q+L
Sbjct: 904 AEAEEMRARLAAKKQELEE----ILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQL 959
Query: 144 DLLKATQMRLK-DAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQE 202
D + + +L+ + A+A + E++ L K + + + + L +E
Sbjct: 960 DEEEGARQKLQLEKVTAEAKIKKMEEEILL-LEDQNSKFIKEKKLMEDRIAECSSQLAEE 1018
Query: 203 DLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISL 262
+ ++ ++I NK + + L LK EK R EK L+ + L + L
Sbjct: 1019 EEKAKNLAKIR--NKQEVMISDLEERLKKEEKT--RQELEKAKRKLDGETTDLQDQIAEL 1074
Query: 263 KSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETV 322
+++I+ LK + + EE +L G L R DE + + V
Sbjct: 1075 QAQIDELKLQLAKKEE-----------------ELQGALARGDDETLHK----NNALKVV 1113
Query: 323 RKCLQTTVAELERQLAASRAQVSTAEKEREELKNRL 358
R+ LQ +AEL+ + +A + AEK++ +L L
Sbjct: 1114 RE-LQAQIAELQEDFESEKASRNKAEKQKRDLSEEL 1148
>AB210026-1|BAE06108.1| 2018|Homo sapiens MYH10 variant protein
protein.
Length = 2018
Score = 56.0 bits (129), Expect = 2e-07
Identities = 78/377 (20%), Positives = 162/377 (42%), Gaps = 27/377 (7%)
Query: 29 ELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQ- 87
E E + + L LM SK+ + NV L++ R ++++E+RT ++E D+LQ
Sbjct: 1543 EFERQNKQLRADMEDLMSSKDDVGK---NVHELEKSKRALEQQVEEMRTQLEELEDELQA 1599
Query: 88 --DYRVKYLQAQQLVEEQ-RRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPD 144
D +++ Q ++ Q R N + +++ ++ + +++ ++ A
Sbjct: 1600 TEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVA 1659
Query: 145 LLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDL 204
K ++ LKD + A +++ ++L + ++ R L +++++
Sbjct: 1660 SKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQREL------EEARASRDEI 1713
Query: 205 FGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKS 264
F QS+ + + + L L E+ R E++ L I+ A +L
Sbjct: 1714 FAQSKESEKKLKSLEAEILQLQEELASSER--ARRHAEQERDELADEITNSASGKSALLD 1771
Query: 265 EIERLKASVIRTE---ESALANEKRLQEKMHECA----QLGGELDRTRDEASRALQRAHE 317
E RL+A + + E E +N + L ++ + L EL R A ++ A +
Sbjct: 1772 EKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKS-DNARQ 1830
Query: 318 QTETVRKCLQTTVAELERQLAAS-RAQVSTAEKEREELKNRLHWQMK-RLTEN--FEQAQ 373
Q E K L+ + ELE + + +A +S E + +L+ +L + K R N + +
Sbjct: 1831 QLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTE 1890
Query: 374 LRILGLQTQVQSLRRTA 390
++ + QV+ RR A
Sbjct: 1891 KKLKEIFMQVEDERRHA 1907
Score = 38.3 bits (85), Expect = 0.049
Identities = 69/336 (20%), Positives = 139/336 (41%), Gaps = 35/336 (10%)
Query: 27 LRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQND-- 84
L ++ + E L L+ KE+ + E + +++ +++ EE + L ++ + +
Sbjct: 886 LLQVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELF 945
Query: 85 -QLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIP 143
+ ++ R + +Q +EE E+ N +Q K K Q +Q+L
Sbjct: 946 AEAEEMRARLAAKKQELEE----ILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQL 1001
Query: 144 DLLKATQMRLK-DAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQE 202
D + + +L+ + A+A + E++ L K + + + + L +E
Sbjct: 1002 DEEEGARQKLQLEKVTAEAKIKKMEEEILL-LEDQNSKFIKEKKLMEDRIAECSSQLAEE 1060
Query: 203 DLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISL 262
+ ++ ++I NK + + L LK EK R EK L+ + L + L
Sbjct: 1061 EEKAKNLAKIR--NKQEVMISDLEERLKKEEKT--RQELEKAKRKLDGETTDLQDQIAEL 1116
Query: 263 KSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETV 322
+++I+ LK + + EE +L G L R DE + + V
Sbjct: 1117 QAQIDELKLQLAKKEE-----------------ELQGALARGDDETLHK----NNALKVV 1155
Query: 323 RKCLQTTVAELERQLAASRAQVSTAEKEREELKNRL 358
R+ LQ +AEL+ + +A + AEK++ +L L
Sbjct: 1156 RE-LQAQIAELQEDFESEKASRNKAEKQKRDLSEEL 1190
>X78998-1|CAA55632.1| 1411|Homo sapiens endosomal protein protein.
Length = 1411
Score = 55.6 bits (128), Expect = 3e-07
Identities = 74/385 (19%), Positives = 161/385 (41%), Gaps = 21/385 (5%)
Query: 24 QNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQN 83
Q+K +EL L T L +E + E +++ K+ Y ++ +EL +K+
Sbjct: 677 QDKQQELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQIKKLE 736
Query: 84 DQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLE---IQRVKLKFQEKLQELA 140
+ + QA Q +++QR+ T +S+Q+ +E + +L Q+K + L
Sbjct: 737 ADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKSEALE 796
Query: 141 PIPD-LLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRY-LYSLYLVTTMT 198
I L K + + Q + +++ Q N + V + + + L+T ++
Sbjct: 797 SIKQKLTKQEEEKQILKQDFETLSQETKIQHEELNNRIQTTVTELQKVKMEKEALMTELS 856
Query: 199 LTQE------DLFGQSQSEIGRGNKDQTVHVL-LHNSLK--PPEKPPERGGDEKQMALLN 249
++ D S+SE + N+ +L L + K + + K+ L
Sbjct: 857 TVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKELKHQLQVQMENTLKEQKELK 916
Query: 250 QRISQLAENNISLKSEIERLKASVIRTEESALANEK---RLQEKMHECAQLGGELDRTRD 306
+ + + E + LK E+ ++ +I+ + + NEK +LQ ++E Q + + +
Sbjct: 917 KSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQGNINELKQSSEQKKKQIE 976
Query: 307 EASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLT 366
L+ A Q + LQ + + ++LAA + ++S + E+ + K+L
Sbjct: 977 ALQGELKIAVLQKTELENKLQQQLTQAAQELAAEKEKISVLQNNYEKSQE----TFKQLQ 1032
Query: 367 ENFEQAQLRILGLQTQVQSLRRTAS 391
+F + +L + ++S+ S
Sbjct: 1033 SDFYGRESELLATRQDLKSVEEKLS 1057
Score = 50.4 bits (115), Expect = 1e-05
Identities = 70/396 (17%), Positives = 165/396 (41%), Gaps = 31/396 (7%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQC----YREAREEIDE 74
Q + Q KL LE + + T++ L ++ +Q +AL+Q REA+ ++++
Sbjct: 454 QVADLQLKLSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQSTTAKLREAQNDLEQ 513
Query: 75 LRTLMKEQNDQLQDYRVKYLQAQQ---LVEEQRRQXXXXXXX--------------NTRI 117
+ + +++ ++Q+ ++++ L+E++R N +
Sbjct: 514 VLRQIGDKDQKIQNLEALLQKSKENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHTL 573
Query: 118 SEQINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCA 177
EQ+ +++K + + Q + D ++ + L+ AQ E + +L +LN +
Sbjct: 574 QEQVTQLTEKLKNQSESHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQLNES 633
Query: 178 REKVVHI---FRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEK 234
+EKV + + L L T + Q+ + + L + + +
Sbjct: 634 KEKVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHLDTAQNALQDKQQELNKITTQLDQV 693
Query: 235 PPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESAL---ANEKRLQEKM 291
+ ++ + L + + E +SL+ + E L+ + + E +L A++++ + +
Sbjct: 694 TAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQIKKLEADSLEVKASKEQALQDL 753
Query: 292 HECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKER 351
+ QL +L+ E S+ L+ E + R LQ LE + + +++ E+E+
Sbjct: 754 QQQRQLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKSEALE----SIKQKLTKQEEEK 809
Query: 352 EELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLR 387
+ LK + E+ RI T++Q ++
Sbjct: 810 QILKQDFETLSQETKIQHEELNNRIQTTVTELQKVK 845
Score = 49.2 bits (112), Expect = 3e-05
Identities = 72/365 (19%), Positives = 158/365 (43%), Gaps = 33/365 (9%)
Query: 48 KEQAFEQEVNVRALKQCYREAREEIDE-------LRTLMKEQNDQLQDYRVKYLQAQQLV 100
KE+ E E + LK +++ +++ +E L++ + + + +L + + +A +
Sbjct: 378 KEELSEVETKYQHLKAEFKQLQQQREEKEQHGLQLQSEINQLHSKLLETERQLGEAHGRL 437
Query: 101 EEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQ 160
+EQR+ + + L++ R++ + +EK+ + L T+ + ++ Q Q
Sbjct: 438 KEQRQLSSEKLMDKEQQVADLQLKLSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQ 497
Query: 161 AI-------AEHNAEQLARELNCAREKVVHIFRYLY-SLYLVTTMTLTQEDLFGQSQSEI 212
A+++ EQ+ R++ +K+ ++ L S ++ + +EDL+ + Q+
Sbjct: 498 QSTTAKLREAQNDLEQVLRQIGDKDQKIQNLEALLQKSKENISLLEKEREDLYAKIQAGE 557
Query: 213 GR----GNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIER 268
G + H L + EK + KQ A N Q+ E L++ +R
Sbjct: 558 GETAVLNQLQEKNHTLQEQVTQLTEKLKNQSESHKQ-AQENLH-DQVQEQKAHLRAAQDR 615
Query: 269 LKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRD-----EASRALQRAHEQT--ET 321
V+ E S +L E + +QL ++ + EA++ QRA Q +T
Sbjct: 616 ----VLSLETSVNELNSQLNESKEKVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHLDT 671
Query: 322 VRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQLRILGLQT 381
+ LQ EL + + QV+ ++++E ++L +K E + + + L+
Sbjct: 672 AQNALQDKQQELNK-ITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEG 730
Query: 382 QVQSL 386
Q++ L
Sbjct: 731 QIKKL 735
Score = 46.8 bits (106), Expect = 1e-04
Identities = 72/361 (19%), Positives = 138/361 (38%), Gaps = 16/361 (4%)
Query: 22 ETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQ-EVNVRALKQCYREAREEIDELRTLMK 80
+ Q K L+ + L S +QA E V+ K R A++ + L T +
Sbjct: 565 QLQEKNHTLQEQVTQLTEKLKNQSESHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVN 624
Query: 81 EQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELA 140
E N QL + + K Q ++ + T + + + Q+K QEL
Sbjct: 625 ELNSQLNESKEKVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHLDTAQNALQDKQQELN 684
Query: 141 PIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLT 200
I L +L+D Q+ + E + ++ + +K + + L +
Sbjct: 685 KITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQIKKLEADSLEVKA 744
Query: 201 QEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEK----PPERGGDEKQMAL--LNQRISQ 254
++ Q + + N D + + EK +K AL + Q++++
Sbjct: 745 SKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKSEALESIKQKLTK 804
Query: 255 LAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQR 314
E LK + E L + + L N R+Q + E ++ E + E L
Sbjct: 805 QEEEKQILKQDFETLSQET-KIQHEELNN--RIQTTVTELQKVKMEKEALMTE----LST 857
Query: 315 AHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQL 374
++ V L+ + +E E++ +A + EK +ELK++L QM+ + EQ +L
Sbjct: 858 VKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKELKHQLQVQMENTLK--EQKEL 915
Query: 375 R 375
+
Sbjct: 916 K 916
Score = 45.6 bits (103), Expect = 3e-04
Identities = 78/340 (22%), Positives = 145/340 (42%), Gaps = 57/340 (16%)
Query: 22 ETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQ----EVNVRALKQCYREAREEIDELRT 77
E L++ E K +GL T ++ + S EQ E+ N++ +K + + + +L T
Sbjct: 114 EKYQGLQQQEAKPDGLVTDSSAELQSLEQQLEEAQTENFNIKQMKDLFEQ---KAAQLAT 170
Query: 78 LMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQ 137
++ D + KY + + L E ++ TR++E++N E + Q+
Sbjct: 171 -------EIADIKSKYDEERSLREAAEQKV-------TRLTEELNKEATVI----QDLKT 212
Query: 138 ELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTM 197
EL P + ++ K+ Q Q + ++ + RE EK+ + L S Y +
Sbjct: 213 ELLQRPGIEDVAVLK-KELVQVQTLMDNMTLERERE----SEKLKDECKKLQSQYASSEA 267
Query: 198 TLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAE 257
T++Q +SE+ +G ++ V+V LK + L Q+ L E
Sbjct: 268 TISQ------LRSELAKGPQEVAVYVQELQKLK------------SSVNELTQKNQTLTE 309
Query: 258 NNISLKSEIERLKASVIRTEESALANEKRLQEKMH----ECAQLGGELDRTRDEASRALQ 313
N LK E + K EES ++K +Q +H +C QL L + R
Sbjct: 310 N--LLKKEQDYTKLEEKHNEESV--SKKNIQATLHQKDLDCQQLQSRLSASETSLHRIHV 365
Query: 314 RAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREE 353
E+ E +K L+ ++E+E + +A+ +++REE
Sbjct: 366 ELSEKGEATQK-LKEELSEVETKYQHLKAEFKQLQQQREE 404
Score = 45.6 bits (103), Expect = 3e-04
Identities = 53/270 (19%), Positives = 109/270 (40%), Gaps = 8/270 (2%)
Query: 120 QINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCARE 179
+I++E+ Q+ +EL+ + + + K QQ + E + QL E+N
Sbjct: 362 RIHVELSEKGEATQKLKEELSEVETKYQHLKAEFKQLQQQREEKEQHGLQLQSEINQLHS 421
Query: 180 KVVHIFRYLYSLY--LVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPE 237
K++ R L + L L+ E L + Q K + L + +
Sbjct: 422 KLLETERQLGEAHGRLKEQRQLSSEKLMDKEQQVADLQLKLSRLEEQLKEKVTNSTELQH 481
Query: 238 RGGDEKQMALLNQRISQLAENNI-SLKSEIERLKASVIRTEESALANEKRLQEKMHECAQ 296
+ KQ Q + Q + ++++E++ I ++ + N + L +K E
Sbjct: 482 QLDKTKQQHQEQQALQQSTTAKLREAQNDLEQVLRQ-IGDKDQKIQNLEALLQKSKENIS 540
Query: 297 LGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKN 356
L L++ R++ +Q +T + + LQ L+ Q+ ++ + ++ +
Sbjct: 541 L---LEKEREDLYAKIQAGEGETAVLNQ-LQEKNHTLQEQVTQLTEKLKNQSESHKQAQE 596
Query: 357 RLHWQMKRLTENFEQAQLRILGLQTQVQSL 386
LH Q++ + AQ R+L L+T V L
Sbjct: 597 NLHDQVQEQKAHLRAAQDRVLSLETSVNEL 626
Score = 39.1 bits (87), Expect = 0.028
Identities = 38/131 (29%), Positives = 62/131 (47%), Gaps = 10/131 (7%)
Query: 225 LHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANE 284
LH+ +K E ++ E+ A L +I+ L EN ++K E + +S R E E
Sbjct: 1218 LHSEIKEKEVGMKK--HEENEAKLTMQITALNENLGTVKKEWQ---SSQRRVSEL----E 1268
Query: 285 KRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQV 344
K+ + E A L + +DE L+R + + K LQT V EL+R+L + A V
Sbjct: 1269 KQTDDLRGEIAVLEATVQNNQDERRALLERCLKGEGEIEK-LQTKVLELQRKLDNTTAAV 1327
Query: 345 STAEKEREELK 355
+E + L+
Sbjct: 1328 QELGRENQSLQ 1338
Score = 34.7 bits (76), Expect = 0.60
Identities = 67/371 (18%), Positives = 154/371 (41%), Gaps = 36/371 (9%)
Query: 48 KEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQX 107
KEQ E + ++ K+ + + E++ ++ + + + L+ + Q Q + E ++
Sbjct: 910 KEQK-ELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQGNINELKQSS 968
Query: 108 XXXXXXNTRISEQINLEIQRVKLKFQEKLQE-LAPIPDLLKATQMRLKDAQQAQAIAEHN 166
+ ++ + + + K + + KLQ+ L L A + ++ Q ++
Sbjct: 969 EQKKKQIEALQGELKIAVLQ-KTELENKLQQQLTQAAQELAAEKEKISVLQNNYEKSQET 1027
Query: 167 AEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKD----QTVH 222
+QL + +++ + L S+ ++L QEDL ++++IG NK +T
Sbjct: 1028 FKQLQSDFYGRESELLATRQDLKSVE--EKLSLAQEDLIS-NRNQIGNQNKLIQELKTAK 1084
Query: 223 VLLH-NSLKPPEKPPER-----------GGDEKQMALLNQRISQLAENNISLKSEIERLK 270
L +S K ++ ER EK++ +++++ E + EI +L
Sbjct: 1085 ATLEQDSAKKEQQLQERCKALQDIQKEKSLKEKELVNEKSKLAEIEEIKCRQEKEITKLN 1144
Query: 271 ASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTV 330
+ + ++ L++ Q EL D A+++ + ++ ++
Sbjct: 1145 EELKSHKLESIKEITNLKDAKQLLIQQKLELQGKADSLKAAVEQEKRNQQILKDQVKKEE 1204
Query: 331 AELERQLAASRAQVSTAEKER-------EELKNRLHWQMKRLTEN-------FEQAQLRI 376
EL+++ A++ + KE+ EE + +L Q+ L EN ++ +Q R+
Sbjct: 1205 EELKKEFIEKEAKLHSEIKEKEVGMKKHEENEAKLTMQITALNENLGTVKKEWQSSQRRV 1264
Query: 377 LGLQTQVQSLR 387
L+ Q LR
Sbjct: 1265 SELEKQTDDLR 1275
Score = 32.7 bits (71), Expect = 2.4
Identities = 32/129 (24%), Positives = 56/129 (43%), Gaps = 9/129 (6%)
Query: 262 LKSEIERLKASVIRTEESALANE-KRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTE 320
L+ E++ L+AS+ EE + E K+ EK Q + D ++S LQ +Q E
Sbjct: 88 LRQEVQDLQASL--KEEKWYSEELKKELEKYQGLQQQEAKPDGLVTDSSAELQSLEQQLE 145
Query: 321 TVR------KCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQL 374
+ K ++ + QLA A + + E L+ ++ RLTE +
Sbjct: 146 EAQTENFNIKQMKDLFEQKAAQLATEIADIKSKYDEERSLREAAEQKVTRLTEELNKEAT 205
Query: 375 RILGLQTQV 383
I L+T++
Sbjct: 206 VIQDLKTEL 214
Score = 32.3 bits (70), Expect = 3.2
Identities = 26/143 (18%), Positives = 69/143 (48%), Gaps = 5/143 (3%)
Query: 244 QMALLNQRISQLAENNISLKS--EIERLKASVIRTEESALANEKRLQEKMHECAQLGGEL 301
++ L Q++ + N ++K ++ KA+ + TE + + ++ + + E A+ ++
Sbjct: 136 ELQSLEQQLEEAQTENFNIKQMKDLFEQKAAQLATEIADIKSKYDEERSLREAAEQ--KV 193
Query: 302 DRTRDEASRALQRAHE-QTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHW 360
R +E ++ + +TE +++ VA L+++L + + ERE +L
Sbjct: 194 TRLTEELNKEATVIQDLKTELLQRPGIEDVAVLKKELVQVQTLMDNMTLERERESEKLKD 253
Query: 361 QMKRLTENFEQAQLRILGLQTQV 383
+ K+L + ++ I L++++
Sbjct: 254 ECKKLQSQYASSEATISQLRSEL 276
>U19769-1|AAA82889.1| 3210|Homo sapiens CENP-F kinetochore protein
protein.
Length = 3210
Score = 55.6 bits (128), Expect = 3e-07
Identities = 74/367 (20%), Positives = 155/367 (42%), Gaps = 30/367 (8%)
Query: 22 ETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNV-RALKQCYRE----------ARE 70
E +N++ +L + E L + L ++ +++NV +AL+ E +E
Sbjct: 2149 ELENQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQE 2208
Query: 71 EIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKL 130
E+ +LR +++ +++ K L + ++E+ R+ + ++ + + +L
Sbjct: 2209 EVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQEL 2268
Query: 131 KFQEKLQELAPIPDL---LKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRY 187
+ A + L ++ LK + E L +++ + ++ + +
Sbjct: 2269 VILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKL 2328
Query: 188 LYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKP-PEKPPERGGDEKQMA 246
L S +L +E + Q+EI + +T +L N LK E GD++ M
Sbjct: 2329 LSSF-----KSLLEE----KEQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQEIMK 2379
Query: 247 LLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGG---ELDR 303
Q + E L++ IE+L+A + E+ L ++L+E H L G L+R
Sbjct: 2380 ATEQSLDPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVENLER 2439
Query: 304 TRDEASRALQRAHEQTETVRKCLQTTVAELE---RQLAASRAQVSTAEKEREELKNRLHW 360
+ A + A + E + ++T A++E + L V T E+E+L N L
Sbjct: 2440 ELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKEDLTNELQK 2499
Query: 361 QMKRLTE 367
+ +R++E
Sbjct: 2500 EQERISE 2506
Score = 48.0 bits (109), Expect = 6e-05
Identities = 66/373 (17%), Positives = 158/373 (42%), Gaps = 29/373 (7%)
Query: 22 ETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKE 81
+ +N REL+M E SK + + + + + + ++ LR+ +
Sbjct: 2251 KVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKEN 2310
Query: 82 QNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAP 141
Q+Q+ + + + +L+ + +I E+ ++ ++ + +E + +A
Sbjct: 2311 LTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVAA 2370
Query: 142 I---PDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLY-SLYLVTTM 197
+ +++KAT+ L + + ++ E+L L +K + + + L S + +
Sbjct: 2371 LCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLL 2430
Query: 198 TLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAE 257
E+L + + EI R N++ H +L E + ++ L +I + +
Sbjct: 2431 KGRVENL--ERELEIARTNQE-------HAAL-------EAENSKGEVETLKAKIEGMTQ 2474
Query: 258 NNISLKSEIERLKASVIRTEESALANE-KRLQEKMHECAQLGGELDRTRDEASRALQRAH 316
+ L+ ++ IR+E+ L NE ++ QE++ E + + E + +
Sbjct: 2475 SLRGLELDVV-----TIRSEKEDLTNELQKEQERISELEIINSSFENILQEKEQEKVQMK 2529
Query: 317 EQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNR---LHWQMKRLTENFEQAQ 373
E++ T + LQT + EL ++AA + + + L ++ L + +L + ++A+
Sbjct: 2530 EKSSTAMEMLQTQLKELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEAK 2589
Query: 374 LRILGLQTQVQSL 386
+ LQ+ V L
Sbjct: 2590 NNYIVLQSSVNGL 2602
Score = 46.0 bits (104), Expect = 2e-04
Identities = 70/324 (21%), Positives = 140/324 (43%), Gaps = 29/324 (8%)
Query: 24 QNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQN 83
Q+ L L+ ++ L + K +F ++VN K+ E + E+ E+ E
Sbjct: 2676 QDTLEVLQSSYKNLENELELTKMDK-MSFVEKVNKMTAKET--ELQREMHEMAQKTAELQ 2732
Query: 84 DQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIP 143
++L + + QL+ E+ + T + ++ + + ++++++ +
Sbjct: 2733 EELSGEKNRLAGELQLLLEEIKSSKDQLKELTLENSELKKSLDCMH---KDQVEKEGKVR 2789
Query: 144 DLLKATQMRLKDAQQA-QAIAEHNAEQLARELNCAREKVVHIFRYLYSLYL-VTTMTLTQ 201
+ + Q+RL +A++ QA+ +Q E+ REK+ L S L + + ++
Sbjct: 2790 EEIAEYQLRLHEAEKKHQALLLDTNKQYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSK 2849
Query: 202 EDLFG------QSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQL 255
E+L Q E+ + D +V N LK K ER + +M LL + QL
Sbjct: 2850 EELNNSLKATTQILEELKKTKMDNLKYV---NQLK---KENERA--QGKMKLLIKSCKQL 2901
Query: 256 AENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQR- 314
E L+ E+ +L+A+ + + + + K + E E +L L+ EA L +
Sbjct: 2902 EEEKEILQKELSQLQAAQEKQKTGTVMDTK-VDELTTEIKELKETLEEKTKEADEYLDKY 2960
Query: 315 -----AHEQTETVRKCLQTTVAEL 333
+HE+ E ++ L+T VA L
Sbjct: 2961 CSLLISHEKLEKAKEMLETQVAHL 2984
Score = 44.4 bits (100), Expect = 7e-04
Identities = 72/334 (21%), Positives = 143/334 (42%), Gaps = 26/334 (7%)
Query: 72 IDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLK 131
+D+L MKE+ +L+ ++ + L Q+ E + ++ +S ++ E+ + K
Sbjct: 2073 LDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQT---LSSDVS-ELLKDKTH 2128
Query: 132 FQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSL 191
QEKLQ L L T+ L++ Q AQ E E L +E + ++ ++
Sbjct: 2129 LQEKLQSLEKDSQALSLTKCELEN-QIAQLNKE--KELLVKESESLQARLSESDYEKLNV 2185
Query: 192 YLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPER-GGDEKQMALLNQ 250
L ++ F S + + VH L EK R DEK+ + +
Sbjct: 2186 SKALEAALVEKGEFALRLS-----STQEEVHQLRRGI----EKLRVRIEADEKKQLHIAE 2236
Query: 251 RISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASR 310
++ + N SLK ++E L+ + +EE+ E + + + A++ L +E +R
Sbjct: 2237 KLKERERENDSLKDKVENLERELQMSEEN---QELVILDAENSKAEV-ETLKTQIEEMAR 2292
Query: 311 ALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFE 370
+L+ T+R + L +Q+ + Q+S +K K+ L + + + E
Sbjct: 2293 SLKVFELDLVTLR----SEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKE 2348
Query: 371 QAQLRILGLQTQVQSLRRTASSTGDGDGENQECT 404
+++ + LQ Q++ L ++ GD E + T
Sbjct: 2349 ESKTAVEMLQNQLKELNEAVAAL-CGDQEIMKAT 2381
Score = 37.9 bits (84), Expect = 0.065
Identities = 61/311 (19%), Positives = 131/311 (42%), Gaps = 18/311 (5%)
Query: 61 LKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQ 120
LK +E R +I+EL ++ +++ K+ + Q +E+ + + + ++
Sbjct: 283 LKAQNQELRNKINELELRLQGHEKEMKGQVNKFQELQLQLEKAKVELIEKEKVLNKCRDE 342
Query: 121 I---NLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCA 177
+ + + K+ Q+L + + L + ++A+ A+ E ++ +E
Sbjct: 343 LVRTTAQYDQASTKYTALEQKLKKLTEDLSCQR---QNAESARCSLEQKIKEKEKEFQEE 399
Query: 178 REKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVL--LHNSLKPPEKP 235
+ F+ L + LTQE ++ + + D+ V L N+L+ ++
Sbjct: 400 LSRQQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQK 459
Query: 236 PERGGDEKQMALLNQR-----ISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEK 290
R Q + + + + ++ + N LKS E+ KA + E+ L N K+ +
Sbjct: 460 LCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQ-KAREVCHLEAELKNIKQCLNQ 518
Query: 291 MHECAQLGGELDRTRDEASRALQRAHEQTE---TVRKCLQTTVAELERQLAASRAQVSTA 347
A+ + +++ R LQ Q E T+ K L+ VA+LE+Q S+ +
Sbjct: 519 SQNFAEEMKAKNTSQETMLRDLQEKINQQENSLTLEK-LKLAVADLEKQRDCSQDLLKKR 577
Query: 348 EKEREELKNRL 358
E E+L ++L
Sbjct: 578 EHHIEQLNDKL 588
Score = 37.5 bits (83), Expect = 0.086
Identities = 60/340 (17%), Positives = 129/340 (37%), Gaps = 11/340 (3%)
Query: 17 RCQHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELR 76
+ Q++E +NK+ ELE++ +G H + G + E ++ + K E + +++ R
Sbjct: 284 KAQNQELRNKINELELRLQG---HEKEMKGQVNKFQELQLQLEKAKVELIEKEKVLNKCR 340
Query: 77 TLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKL 136
+ Q KY +Q +++ + +I+ + +FQE+L
Sbjct: 341 DELVRTTAQYDQASTKYTALEQKLKKLTEDLSCQRQNAESARCSLEQKIKEKEKEFQEEL 400
Query: 137 QELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTT 196
L +++K A+ Q + + A+ + L +K+ + + L +
Sbjct: 401 SRQQRSFQTLDQECIQMK-ARLTQELQQ--AKNMHNVLQAELDKLTSVKQQLENNLEEFK 457
Query: 197 MTLTQ-EDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQL 255
L + E F SQ + + +N LK + R + L N +
Sbjct: 458 QKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNIKQCLN 517
Query: 256 AENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRA 315
N + + + + + + N++ + + +L++ RD + L++
Sbjct: 518 QSQNFAEEMKAKNTSQETMLRDLQEKINQQENSLTLEKLKLAVADLEKQRDCSQDLLKKR 577
Query: 316 HEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELK 355
E + L T E + L+A + +KE EELK
Sbjct: 578 EHHIEQLNDKLSKTEKESKALLSA----LELKKKEYEELK 613
Score = 33.9 bits (74), Expect = 1.1
Identities = 56/308 (18%), Positives = 126/308 (40%), Gaps = 24/308 (7%)
Query: 81 EQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQEL- 139
+Q + +D + L+ Q +EQ ++ ++ NLE++ + ++ ++K+Q L
Sbjct: 2610 KQKLEKKDEEISRLKNQIQDQEQLVSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQ 2669
Query: 140 ---APIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTT 196
A + D L+ Q K+ + + + + ++N K + R ++ + T
Sbjct: 2670 SKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTA 2729
Query: 197 MTLTQEDLFGQSQSEIG---------RGNKDQTVHVLLHNS-LKPPEKPPERGGDEKQMA 246
QE+L G+ G + +KDQ + L NS LK + EK+
Sbjct: 2730 E--LQEELSGEKNRLAGELQLLLEEIKSSKDQLKELTLENSELKKSLDCMHKDQVEKE-- 2785
Query: 247 LLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRD 306
+ ++AE + L ++ +A ++ T + + +EK+ + L +
Sbjct: 2786 --GKVREEIAEYQLRLHEAEKKHQALLLDTNKQYEVEIQTYREKLTSKEEC---LSSQKL 2840
Query: 307 EASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLT 366
E L+ + E+ K + EL++ + V+ +KE E + ++ +K
Sbjct: 2841 EID-LLKSSKEELNNSLKATTQILEELKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCK 2899
Query: 367 ENFEQAQL 374
+ E+ ++
Sbjct: 2900 QLEEEKEI 2907
Score = 32.7 bits (71), Expect = 2.4
Identities = 37/159 (23%), Positives = 63/159 (39%), Gaps = 14/159 (8%)
Query: 240 GDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGG 299
G+ M+ + QL+E E+E ++ + + A A K E + +
Sbjct: 2061 GELDTMSKKTTALDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQTLSSDVS 2120
Query: 300 ELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRL- 358
EL + + LQ + ++ L T ELE Q+A + KE E L+ RL
Sbjct: 2121 ELLKDKTHLQEKLQSLEKDSQA----LSLTKCELENQIAQLNKEKELLVKESESLQARLS 2176
Query: 359 --HWQMKRLTENFEQA-------QLRILGLQTQVQSLRR 388
++ +++ E A LR+ Q +V LRR
Sbjct: 2177 ESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRR 2215
>AF111785-1|AAD29951.1| 1939|Homo sapiens myosin heavy chain IIx/d
protein.
Length = 1939
Score = 55.6 bits (128), Expect = 3e-07
Identities = 81/339 (23%), Positives = 149/339 (43%), Gaps = 37/339 (10%)
Query: 38 ATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQND---QLQDYRVKYL 94
+ T M + ++ FE+ A + R+ EE ++ TLM+E+ND Q+Q
Sbjct: 846 SAETEKEMANMKEEFEKTKEELAKTEAKRKELEE--KMVTLMQEKNDLQLQVQAEADSLA 903
Query: 95 QAQ----QLVEEQRRQXXXXXXXNTRIS--EQINLEIQRVKLKFQEKLQELAPIPDLLKA 148
A+ QL++ + + R E+IN E+ K K +++ EL D L+
Sbjct: 904 DAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLEL 963
Query: 149 TQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQS 208
T +++ + A E+ + L E+ E + + + +L TL +DL
Sbjct: 964 TLAKVEKEKHA---TENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTL--DDL---- 1014
Query: 209 QSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIER 268
Q+E + N + L + E E+ EK++ + +R + E ++ L E
Sbjct: 1015 QAEEDKVNTLTKAKIKLEQQVDDLEGSLEQ---EKKIRMDLERAKRKLEGDLKLAQE--- 1068
Query: 269 LKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQT 328
A I ++ L +++L++K E + L +++ DE + +Q + E LQ
Sbjct: 1069 -SAMDIENDKQQL--DEKLKKKEFEMSGLQSKIE---DEQALGMQLQKKIKE-----LQA 1117
Query: 329 TVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTE 367
+ ELE ++ A RA + AEK+R +L L +RL E
Sbjct: 1118 RIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEE 1156
Score = 42.3 bits (95), Expect = 0.003
Identities = 78/394 (19%), Positives = 162/394 (41%), Gaps = 38/394 (9%)
Query: 22 ETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKE 81
ET +L + + L+T + + E++ +Q + LK+ + ++EI +L + E
Sbjct: 1466 ETHAELEASQKESRSLSTELFKIKNAYEESLDQ---LETLKRENKNLQQEISDLTEQIAE 1522
Query: 82 QNDQLQDY-RVKYLQAQQLVEEQRRQXXXXXXXNTRISE--QINLEIQRVKLKFQEKLQE 138
++ + ++K Q+ E Q + +I LE+ +VK + K+ E
Sbjct: 1523 GGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAE 1582
Query: 139 LAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMT 198
D +K +R+ ++ Q+ AE + A L E ++ L M
Sbjct: 1583 KDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEI--QLNHANRMA 1640
Query: 199 LTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAEN 258
+ +Q+ + KD +H L ++L+ E E Q+A++ +R + L
Sbjct: 1641 AEALRNYRNTQAIL----KDTQLH--LDDALRSQEDLKE------QLAMVERRANLL--- 1685
Query: 259 NISLKSEIERLKASVIRTEESALANEKRL---QEKMHECAQLGGELDRTRDEASRALQRA 315
++EIE L+A++ +TE S E+ L E++ L T+ + + +
Sbjct: 1686 ----QAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQI 1741
Query: 316 HEQTETVRKCLQTTVAELERQLAASRAQVSTAEKER------EELKNRLHWQMKRLTENF 369
+ E + + + + ++ + + +KE+ E +K L +K L
Sbjct: 1742 QGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRL 1801
Query: 370 EQA-QLRILGLQTQVQSLR-RTASSTGDGDGENQ 401
++A QL + G + Q+Q L R G+ + E +
Sbjct: 1802 DEAEQLALKGGKKQIQKLEARVRELEGEVESEQK 1835
Score = 41.9 bits (94), Expect = 0.004
Identities = 61/372 (16%), Positives = 145/372 (38%), Gaps = 20/372 (5%)
Query: 21 RETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMK 80
++ KL++ E + GL + + + + + ++ L+ E EEI+ R
Sbjct: 1078 QQLDEKLKKKEFEMSGLQSK---IEDEQALGMQLQKKIKELQARIEELEEEIEAERASRA 1134
Query: 81 EQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELA 140
+ Q D + + + +EE ++++ E Q+++ +E A
Sbjct: 1135 KAEKQRSDLSRELEEISERLEE----AGGATSAQIEMNKKREAEFQKMRRDLEE-----A 1185
Query: 141 PIPDLLKATQMRLKDAQQAQAIAEH--NAEQLARELNCAREKV-VHIFRYLYSLYLVTTM 197
+ A +R K A + E N +++ ++L + ++ + I ++ V+
Sbjct: 1186 TLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKA 1245
Query: 198 TLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEK--PPERGGDEKQMALLNQRISQL 255
E + + ++ + L N L E G +Q+ + +SQL
Sbjct: 1246 KGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQLDEKDTLVSQL 1305
Query: 256 AENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRD---EASRAL 312
+ + +IE LK + ++ A LQ H+C L + + ++ E RA+
Sbjct: 1306 SRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAM 1365
Query: 313 QRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQA 372
+A+ + R +T + +L ++ +++ ++ EE ++ + L + ++
Sbjct: 1366 SKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRL 1425
Query: 373 QLRILGLQTQVQ 384
Q + L V+
Sbjct: 1426 QNEVEDLMIDVE 1437
Score = 41.1 bits (92), Expect = 0.007
Identities = 71/384 (18%), Positives = 164/384 (42%), Gaps = 45/384 (11%)
Query: 24 QNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQN 83
Q ++LE + + + L + E + + N+ K C R +++ E++T +EQ
Sbjct: 1215 QRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLE--KMC-RALEDQLSEIKTKEEEQQ 1271
Query: 84 DQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRIS---EQINLEIQRVKLKFQEKLQELA 140
+ D + + Q E RQ +++S + +I+ +K + +E+++ +
Sbjct: 1272 RLINDLTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKS 1331
Query: 141 PIPDLLKATQMRLKDAQQAQAIAEHNAE-QLARELNCAREKVVHIFRYLYSLYLVTTMTL 199
+ L++++ D + Q E A+ +L R ++ A +V +R Y T +
Sbjct: 1332 ALAHALQSSRHDC-DLLREQYEEEQEAKAELQRAMSKANSEVAQ-WRTKYE-----TDAI 1384
Query: 200 TQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENN 259
+ + +++ ++ + +D HV N+ + A L + +L
Sbjct: 1385 QRTEELEEAKKKLAQRLQDAEEHVEAVNA---------------KCASLEKTKQRLQNEV 1429
Query: 260 ISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEA----------S 309
L ++ER A+ ++ +K L E +C + EL+ ++ E+
Sbjct: 1430 EDLMIDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLSTELFKIK 1489
Query: 310 RALQRAHEQTETVR---KCLQTTVAELERQLAASRAQVSTAE---KEREELKNRLHWQMK 363
A + + +Q ET++ K LQ +++L Q+A ++ E K+ E+ K+ L ++
Sbjct: 1490 NAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALE 1549
Query: 364 RLTENFEQAQLRILGLQTQVQSLR 387
+ E + +IL +Q ++ ++
Sbjct: 1550 EAEASLEHEEGKILRIQLELNQVK 1573
>Z54367-1|CAA91196.1| 4684|Homo sapiens plectin protein.
Length = 4684
Score = 55.2 bits (127), Expect = 4e-07
Identities = 72/378 (19%), Positives = 160/378 (42%), Gaps = 14/378 (3%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTL 78
+ +E Q L++ + + L + E+A E V R EE + L+
Sbjct: 2198 KEQELQQTLQQEQSVLDRLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQS 2257
Query: 79 MKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQE 138
+EQ + + ++ E++ + R + + E+++ K ++ L++
Sbjct: 2258 AEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQ 2317
Query: 139 LAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYL-VTTM 197
A + L +++L++ + + + ++L E A + + L+S+ + + +
Sbjct: 2318 KAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEEL 2377
Query: 198 TLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAE 257
+ + + ++++ I R +KD T L + K ++ E A R+ QLAE
Sbjct: 2378 SKLKARIEAENRALILR-DKDNTQRFLQEEAEK-MKQVAEEAARLSVAAQEAARLRQLAE 2435
Query: 258 NNISLKSEI--ERLKASVIRTEESA-LANEKRLQEKMHECAQLGGELDRTRDEASRALQR 314
+++ + + + LK + +E+ L E L ++ E AQ + R +++ + Q+
Sbjct: 2436 EDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQ--EQARRLQEDKEQMAQQ 2493
Query: 315 AHEQTETVRKCLQT-TVAELERQLAASR-----AQVSTAEKEREELKNRLHWQMKRLTEN 368
E+T+ ++ L+ +LE A R A++S A+ EE R Q + + E
Sbjct: 2494 LAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEK 2553
Query: 369 FEQAQLRILGLQTQVQSL 386
+ +L T VQ+L
Sbjct: 2554 LHRTELATQEKVTLVQTL 2571
Score = 48.0 bits (109), Expect = 6e-05
Identities = 63/332 (18%), Positives = 137/332 (41%), Gaps = 16/332 (4%)
Query: 49 EQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXX 108
EQ Q+ V R EE D + L+ E+ +L+ + + + VEE+
Sbjct: 2312 EQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVR 2371
Query: 109 XXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAE 168
+++ +I E + + L+ ++ Q L+ ++K + A A+
Sbjct: 2372 VQMEELSKLKARIEAENRALILRDKDNTQRF------LQEEAEKMKQVAEEAARLSVAAQ 2425
Query: 169 QLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNS 228
+ AR A E + R L L M QE ++++E+ + K+
Sbjct: 2426 EAARLRQLAEEDLAQQ-RALAEKMLKEKMQAVQEATRLKAEAELLQQQKE-LAQEQARRL 2483
Query: 229 LKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQ 288
+ E+ ++ +E Q + + + + + +E ERLK V + E+ Q
Sbjct: 2484 QEDKEQMAQQLAEETQG--FQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQ 2541
Query: 289 EKMHECAQLGGELDRT----RDEAS--RALQRAHEQTETVRKCLQTTVAELERQLAASRA 342
+ ++G +L RT +++ + + L+ +Q++ + L+ +AELER+ +
Sbjct: 2542 RFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQ 2601
Query: 343 QVSTAEKEREELKNRLHWQMKRLTENFEQAQL 374
+ + + EE++ Q+ + T+ +Q+ L
Sbjct: 2602 EAKLLQLKSEEMQTVQQEQLLQETQALQQSFL 2633
Score = 46.4 bits (105), Expect = 2e-04
Identities = 74/345 (21%), Positives = 147/345 (42%), Gaps = 20/345 (5%)
Query: 21 RETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRAL-KQCYREAREEIDELRTLM 79
+E K++++ + L+ ++ A E RAL ++ +E + + E L
Sbjct: 2404 QEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLK 2463
Query: 80 KEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQEL 139
E Q + QA++L E++ + + E QR +L+ + + L
Sbjct: 2464 AEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQR-QLEMSAEAERL 2522
Query: 140 A-PIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMT 198
+ ++ +A +DAQ+ + AE E+L R +EKV + +L + +
Sbjct: 2523 KLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLV----QTLEIQRQQS 2578
Query: 199 LTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQ--LA 256
+ ++ +E+ R K++ LK E + ++Q+ Q + Q L+
Sbjct: 2579 DHDAERLREAIAELER-EKEKLQQEAKLLQLKSEEMQTVQ---QEQLLQETQALQQSFLS 2634
Query: 257 ENNISLKSE--IERLKASVIRTEESALANEKRL-QEKMHECAQLGGELDRTRDEASRALQ 313
E + L+ E IE+ KA + + + +A ++L +E+ + Q+ E R A +
Sbjct: 2635 EKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARR 2694
Query: 314 RAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRL 358
R HE E VR+ Q + +LE+Q R Q +E + L+ +L
Sbjct: 2695 RQHEAEEGVRR-KQEELQQLEQQ---RRQQEELLAEENQRLREQL 2735
Score = 45.2 bits (102), Expect = 4e-04
Identities = 76/366 (20%), Positives = 145/366 (39%), Gaps = 13/366 (3%)
Query: 29 ELEMKFEGLATHTNMLMGSKEQAFEQ-EVNVRALKQCYREAREEIDELRTLMKEQNDQLQ 87
+L + L T T+ + + + E R +Q E RE + E+ +++Q QL
Sbjct: 1455 DLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQR-QLA 1513
Query: 88 DYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDL-L 146
+ + QA+ E + ++ E+ ++ Q+ K QE+LQ+L + +
Sbjct: 1514 E---AHAQAKAQAEREAKELQQRIQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEI 1570
Query: 147 KATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFG 206
+A + + A++++ E + +L + L +L Q+
Sbjct: 1571 QAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQ 1630
Query: 207 QSQSEIGRGNKDQTVHVLLHN-SLKPPEKPPERGGDEKQMAL--LNQRISQLAENNISL- 262
+ + R +D++ L K EKQ AL L + Q E L
Sbjct: 1631 EEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERWLC 1690
Query: 263 KSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETV 322
++E+ER + + E + + E LQ K A+ +L+R+ E A+ + E+ E
Sbjct: 1691 QAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAE-- 1748
Query: 323 RKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQLRILGLQTQ 382
R+ Q AE R+ A R K E L+ RL + ++ QA+ + +
Sbjct: 1749 RRAQQQAEAERARE-EAERQLERWQLKANEALRLRLQAEEVLQQKSLAQAEAEKQKEEAE 1807
Query: 383 VQSLRR 388
++ RR
Sbjct: 1808 REARRR 1813
Score = 44.0 bits (99), Expect = 0.001
Identities = 79/373 (21%), Positives = 145/373 (38%), Gaps = 32/373 (8%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTL 78
+ R Q R+L++ E A + K AF + + L+Q ++ + +D LR
Sbjct: 2162 RERAEQESARQLQLAQE--AAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDRLRGE 2219
Query: 79 MKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQE 138
+ ++ +QA++ + RRQ E +R+K +E+ Q
Sbjct: 2220 AEAARRAAEEAEEARVQAEREAAQSRRQVE---------------EAERLKQSAEEQAQA 2264
Query: 139 LAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMT 198
A +A +L+ + +A AEQ A A + + + L
Sbjct: 2265 RAQ----AQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQ 2320
Query: 199 LTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAEN 258
+ QE + Q E K+ L + E +R E+++ + ++ +L++
Sbjct: 2321 VEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSK- 2379
Query: 259 NISLKSEIE-RLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHE 317
LK+ IE +A ++R +++ + EKM + A+ L EA+R Q A E
Sbjct: 2380 ---LKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEE 2436
Query: 318 QTETVRKCLQTTVAELERQLAASRAQVSTAEKE-REELKNRLHWQMKRLTENFEQAQLRI 376
R + + E+ A A AE E ++ K Q +RL E+ EQ +
Sbjct: 2437 DLAQQRALAEKMLK--EKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQ- 2493
Query: 377 LGLQTQVQSLRRT 389
L + Q +RT
Sbjct: 2494 --LAEETQGFQRT 2504
Score = 39.9 bits (89), Expect = 0.016
Identities = 90/407 (22%), Positives = 149/407 (36%), Gaps = 45/407 (11%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKEQA---FEQEVNVRALKQCYRE-----ARE 70
Q R Q +L++L E + E++ E+E+ V L+ E A
Sbjct: 1551 QKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEG 1610
Query: 71 EIDELRTLMKE---QNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQR 127
E+ LR +E Q Q Q+ + + Q +++RQ + + E QR
Sbjct: 1611 ELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQR 1670
Query: 128 VKLKFQE-KLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAE-QLARELNCAREKVVHIF 185
+E +LQ L +A R + Q A A+ +AE +L + EK +
Sbjct: 1671 ALQALEELRLQAEEAERWLCQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLE 1730
Query: 186 RYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKD--------------------QTVHVLL 225
R L ++ + + Q Q+E R ++ Q VL
Sbjct: 1731 RSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERQLERWQLKANEALRLRLQAEEVLQ 1790
Query: 226 HNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEK 285
SL E ++ E++ + Q + E+E+ + T + LA E+
Sbjct: 1791 QKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQ 1850
Query: 286 RLQEKMHECAQ-------LGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLA 338
L E Q L EL R + EA+ A Q+ E + K AE+E LA
Sbjct: 1851 ELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVR----AEMEVLLA 1906
Query: 339 ASRAQVSTAEKEREELKNRLHWQMKRLTENFEQ-AQLRILGLQTQVQ 384
+ + E+ K RL + R E E+ A+LR L + + Q
Sbjct: 1907 SKAKAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQ 1953
Score = 38.3 bits (85), Expect = 0.049
Identities = 31/134 (23%), Positives = 57/134 (42%), Gaps = 3/134 (2%)
Query: 47 SKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQ 106
+K Q +E R +Q +E + + + + Q++ + R K + QQL +++R+Q
Sbjct: 2662 AKAQQLREEQQ-RQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQ 2720
Query: 107 XXXXXXXNTRISEQINL--EIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAE 164
N R+ EQ+ L E R L E++ D A+A E
Sbjct: 2721 EELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPE 2780
Query: 165 HNAEQLARELNCAR 178
H+ + L R+++ R
Sbjct: 2781 HSFDGLRRKVSAQR 2794
Score = 36.7 bits (81), Expect = 0.15
Identities = 72/320 (22%), Positives = 130/320 (40%), Gaps = 21/320 (6%)
Query: 48 KEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQL-VEEQRRQ 106
+E+ +E +Q R +EE+ +LR E Q + + + + +L +EE+ R
Sbjct: 1535 QEEVVRREEAAVDAQQQKRSIQEELQQLRQ-SSEAEIQAKARQAEAAERSRLRIEEEIRV 1593
Query: 107 XXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHN 166
R E+Q ++ + +E + + + + +++D Q + AE
Sbjct: 1594 VRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVE 1653
Query: 167 -AEQLARELNCAREKVVHIFRYLYSLYLVTTMT---LTQEDLFGQSQSEIGRGNKDQTVH 222
A ++ E AREK + L L L L Q ++ Q ++ ++
Sbjct: 1654 LASRVKAEAEAAREKQ-RALQALEELRLQAEEAERWLCQAEVERARQVQVALETAQRSAE 1712
Query: 223 VLLHN---SLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEE- 278
L + S ER E+ +A+ R + AE ++E ER + R E
Sbjct: 1713 AELQSKRASFAEKTAQLERSLQEEHVAVAQLR--EEAERRAQQQAEAERAREEAERQLER 1770
Query: 279 -SALANEK---RLQ--EKMHECAQLGGELDRTRDEASR-ALQRAHEQTETVR-KCLQTTV 330
ANE RLQ E + + + E ++ ++EA R A +R + + VR + L
Sbjct: 1771 WQLKANEALRLRLQAEEVLQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQE 1830
Query: 331 AELERQLAASRAQVSTAEKE 350
E +RQLA AQ A ++
Sbjct: 1831 LEKQRQLAEGTAQQRLAAEQ 1850
Score = 34.7 bits (76), Expect = 0.60
Identities = 38/160 (23%), Positives = 76/160 (47%), Gaps = 13/160 (8%)
Query: 27 LRELEMKFEGLATHTNMLMGSKE--QAFEQEV---NVRALKQCYREAREEIDELRTLMKE 81
+ ELE + E L +L E Q +QE +AL+Q + ++ + + +++
Sbjct: 2589 IAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQ 2648
Query: 82 QNDQLQD-YRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELA 140
+ +L+ ++ + +AQQL EEQ+RQ R+ + E +R + + +E ++
Sbjct: 2649 EKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASME-EARRRQHEAEEGVRRKQ 2707
Query: 141 PIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREK 180
+L + Q R QQ + +AE N ++L +L E+
Sbjct: 2708 --EELQQLEQQR---RQQEELLAEEN-QRLREQLQLLEEQ 2741
Score = 33.5 bits (73), Expect = 1.4
Identities = 73/390 (18%), Positives = 157/390 (40%), Gaps = 30/390 (7%)
Query: 17 RCQHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELR 76
R + + + +R+ E+ + L + G+ +Q E + L R E+ ++ R
Sbjct: 1811 RRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRL----RAETEQGEQQR 1866
Query: 77 TLMKEQNDQLQDYRVKYLQAQQLVEEQ----RRQXXXXXXXNTRISEQINLEIQRVKLKF 132
L++E+ +LQ Q +Q +E + R + + E+ ++ K +
Sbjct: 1867 QLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKAKAEEESRSTSEKSKQRL 1926
Query: 133 QEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLY 192
+ + + + + ++A++ + +AE +A + E E+V + L ++
Sbjct: 1927 EAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEA----ERV--LAEKLAAIG 1980
Query: 193 LVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGD-EKQMALLN-- 249
T + E + ++E R + L+ E+ + D E+++A L
Sbjct: 1981 EATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLE--EQAAQHKADIEERLAQLRKA 2038
Query: 250 -----QRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRT 304
+R L E+ + + ++E ++ + E A A + L+ ++ + R+
Sbjct: 2039 SDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRS 2098
Query: 305 RD----EASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHW 360
++ EA+R Q A E+ R+ + L + A+R Q A +E E LK ++
Sbjct: 2099 KEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAAR-QRKAALEEVERLKAKVE- 2156
Query: 361 QMKRLTENFEQAQLRILGLQTQVQSLRRTA 390
+ + L E EQ R L L + R A
Sbjct: 2157 EARSLRERAEQESARQLQLAQEAAQKRLQA 2186
>U63610-1|AAB05428.1| 4574|Homo sapiens plectin protein.
Length = 4574
Score = 55.2 bits (127), Expect = 4e-07
Identities = 72/378 (19%), Positives = 160/378 (42%), Gaps = 14/378 (3%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTL 78
+ +E Q L++ + + L + E+A E V R EE + L+
Sbjct: 2088 KEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQARRQVEEAERLKQS 2147
Query: 79 MKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQE 138
+EQ + + ++ E++ + R + + E+++ K ++ L++
Sbjct: 2148 AEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQ 2207
Query: 139 LAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYL-VTTM 197
A + L +++L++ + + + ++L E A + + L+S+ + + +
Sbjct: 2208 KAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEEL 2267
Query: 198 TLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAE 257
+ + + ++++ I R +KD T L + K ++ E A R+ QLAE
Sbjct: 2268 SKLKARIEAENRALILR-DKDNTQRFLQEEAEK-MKQVAEEAARLSVAAQEAARLRQLAE 2325
Query: 258 NNISLKSEI--ERLKASVIRTEESA-LANEKRLQEKMHECAQLGGELDRTRDEASRALQR 314
+++ + + + LK + +E+ L E L ++ E AQ + R +++ + Q+
Sbjct: 2326 EDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQ--EQARRLQEDKEQMAQQ 2383
Query: 315 AHEQTETVRKCLQT-TVAELERQLAASR-----AQVSTAEKEREELKNRLHWQMKRLTEN 368
E+T+ ++ L+ +LE A R A++S A+ EE R Q + + E
Sbjct: 2384 LAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEK 2443
Query: 369 FEQAQLRILGLQTQVQSL 386
+ +L T VQ+L
Sbjct: 2444 LHRTELATQEKVTLVQTL 2461
Score = 48.0 bits (109), Expect = 6e-05
Identities = 63/332 (18%), Positives = 137/332 (41%), Gaps = 16/332 (4%)
Query: 49 EQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXX 108
EQ Q+ V R EE D + L+ E+ +L+ + + + VEE+
Sbjct: 2202 EQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVR 2261
Query: 109 XXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAE 168
+++ +I E + + L+ ++ Q L+ ++K + A A+
Sbjct: 2262 VQMEELSKLKARIEAENRALILRDKDNTQRF------LQEEAEKMKQVAEEAARLSVAAQ 2315
Query: 169 QLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNS 228
+ AR A E + R L L M QE ++++E+ + K+
Sbjct: 2316 EAARLRQLAEEDLAQQ-RALAEKMLKEKMQAVQEATRLKAEAELLQQQKE-LAQEQARRL 2373
Query: 229 LKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQ 288
+ E+ ++ +E Q + + + + + +E ERLK V + E+ Q
Sbjct: 2374 QEDKEQMAQQLAEETQG--FQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQ 2431
Query: 289 EKMHECAQLGGELDRT----RDEAS--RALQRAHEQTETVRKCLQTTVAELERQLAASRA 342
+ ++G +L RT +++ + + L+ +Q++ + L+ +AELER+ +
Sbjct: 2432 RFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQ 2491
Query: 343 QVSTAEKEREELKNRLHWQMKRLTENFEQAQL 374
+ + + EE++ Q+ + T+ +Q+ L
Sbjct: 2492 EAKLLQLKSEEMQTVQQEQLLQETQALQQSFL 2523
Score = 46.8 bits (106), Expect = 1e-04
Identities = 76/366 (20%), Positives = 145/366 (39%), Gaps = 13/366 (3%)
Query: 29 ELEMKFEGLATHTNMLMGSKEQAFEQ-EVNVRALKQCYREAREEIDELRTLMKEQNDQLQ 87
+L + L T T+ + + + E R +Q E RE + E+ +++Q QL
Sbjct: 1345 DLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQR-QLA 1403
Query: 88 DYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDL-L 146
+ + QA+ E + ++ E+ ++ Q+ K QE+LQ+L + +
Sbjct: 1404 E---AHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEI 1460
Query: 147 KATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFG 206
+A + + A++++ E + +L + L +L Q+
Sbjct: 1461 QAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQ 1520
Query: 207 QSQSEIGRGNKDQTVHVLLHN-SLKPPEKPPERGGDEKQMAL--LNQRISQLAENNISLK 263
+ + R +D++ L K EKQ AL L + Q E L+
Sbjct: 1521 EEAERLRRQVQDESQRKRQAEVELASRVKAETEAAREKQRALQALEELRLQAEEAERRLR 1580
Query: 264 -SEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETV 322
+E+ER + + E + + E LQ K A+ +L+R+ E A+ + E+ E
Sbjct: 1581 QAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAE-- 1638
Query: 323 RKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQLRILGLQTQ 382
R+ Q AE R+ A R K E L+ RL + ++ QA+ + +
Sbjct: 1639 RRAQQQAEAERARE-EAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAE 1697
Query: 383 VQSLRR 388
++ RR
Sbjct: 1698 REARRR 1703
Score = 46.4 bits (105), Expect = 2e-04
Identities = 74/345 (21%), Positives = 147/345 (42%), Gaps = 20/345 (5%)
Query: 21 RETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRAL-KQCYREAREEIDELRTLM 79
+E K++++ + L+ ++ A E RAL ++ +E + + E L
Sbjct: 2294 QEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLK 2353
Query: 80 KEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQEL 139
E Q + QA++L E++ + + E QR +L+ + + L
Sbjct: 2354 AEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQR-QLEMSAEAERL 2412
Query: 140 A-PIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMT 198
+ ++ +A +DAQ+ + AE E+L R +EKV + +L + +
Sbjct: 2413 KLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLV----QTLEIQRQQS 2468
Query: 199 LTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQ--LA 256
+ ++ +E+ R K++ LK E + ++Q+ Q + Q L+
Sbjct: 2469 DHDAERLREAIAELER-EKEKLQQEAKLLQLKSEEMQTVQ---QEQLLQETQALQQSFLS 2524
Query: 257 ENNISLKSE--IERLKASVIRTEESALANEKRL-QEKMHECAQLGGELDRTRDEASRALQ 313
E + L+ E IE+ KA + + + +A ++L +E+ + Q+ E R A +
Sbjct: 2525 EKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARR 2584
Query: 314 RAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRL 358
R HE E VR+ Q + +LE+Q R Q +E + L+ +L
Sbjct: 2585 RQHEAEEGVRR-KQEELQQLEQQ---RRQQEELLAEENQRLREQL 2625
Score = 46.0 bits (104), Expect = 2e-04
Identities = 80/375 (21%), Positives = 147/375 (39%), Gaps = 32/375 (8%)
Query: 17 RCQHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELR 76
R + R Q R+L++ E A + K AF + + L+Q ++ + +D+LR
Sbjct: 2050 RLRERAEQESARQLQLAQE--AAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLR 2107
Query: 77 TLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKL 136
+ ++ +QA++ + RRQ E +R+K +E+
Sbjct: 2108 GEAEAARRAAEEAEEARVQAEREAAQARRQVE---------------EAERLKQSAEEQA 2152
Query: 137 QELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTT 196
Q A +A +L+ + +A AEQ A A + + + L
Sbjct: 2153 QARAQ----AQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQK 2208
Query: 197 MTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLA 256
+ QE + Q E K+ L + E +R E+++ + ++ +L+
Sbjct: 2209 AQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELS 2268
Query: 257 ENNISLKSEIE-RLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRA 315
+ LK+ IE +A ++R +++ + EKM + A+ L EA+R Q A
Sbjct: 2269 K----LKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLA 2324
Query: 316 HEQTETVRKCLQTTVAELERQLAASRAQVSTAEKE-REELKNRLHWQMKRLTENFEQAQL 374
E R + + E+ A A AE E ++ K Q +RL E+ EQ
Sbjct: 2325 EEDLAQQRALAEKMLK--EKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQ 2382
Query: 375 RILGLQTQVQSLRRT 389
+ L + Q +RT
Sbjct: 2383 Q---LAEETQGFQRT 2394
Score = 38.3 bits (85), Expect = 0.049
Identities = 89/407 (21%), Positives = 148/407 (36%), Gaps = 45/407 (11%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKEQA---FEQEVNVRALKQCYRE-----ARE 70
Q R Q +L++L E + E++ E+E+ V L+ E A
Sbjct: 1441 QKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEG 1500
Query: 71 EIDELRTLMKE---QNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQR 127
E+ LR +E Q Q Q+ + + Q +++RQ + + E QR
Sbjct: 1501 ELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAETEAAREKQR 1560
Query: 128 VKLKFQE-KLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAE-QLARELNCAREKVVHIF 185
+E +LQ L +A R + Q A A+ +AE +L + EK +
Sbjct: 1561 ALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLE 1620
Query: 186 RYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKD--------------------QTVHVLL 225
R L ++ + + Q Q+E R ++ Q V
Sbjct: 1621 RSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQ 1680
Query: 226 HNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEK 285
SL E ++ E++ + Q + E+E+ + T + LA E+
Sbjct: 1681 QKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQ 1740
Query: 286 RLQEKMHECAQ-------LGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLA 338
L E Q L EL R + EA+ A Q+ E + K AE+E LA
Sbjct: 1741 ELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVR----AEMEVLLA 1796
Query: 339 ASRAQVSTAEKEREELKNRLHWQMKRLTENFEQ-AQLRILGLQTQVQ 384
+ + E+ K RL + R E E+ A+LR L + + Q
Sbjct: 1797 SKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQ 1843
Score = 38.3 bits (85), Expect = 0.049
Identities = 31/134 (23%), Positives = 57/134 (42%), Gaps = 3/134 (2%)
Query: 47 SKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQ 106
+K Q +E R +Q +E + + + + Q++ + R K + QQL +++R+Q
Sbjct: 2552 AKAQQLREEQQ-RQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQ 2610
Query: 107 XXXXXXXNTRISEQINL--EIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAE 164
N R+ EQ+ L E R L E++ D A+A E
Sbjct: 2611 EELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPE 2670
Query: 165 HNAEQLARELNCAR 178
H+ + L R+++ R
Sbjct: 2671 HSFDGLRRKVSAQR 2684
Score = 36.3 bits (80), Expect = 0.20
Identities = 75/390 (19%), Positives = 157/390 (40%), Gaps = 30/390 (7%)
Query: 17 RCQHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELR 76
R + + + +R+ E+ + L + G+ +Q E + L R E+ ++ R
Sbjct: 1701 RRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRL----RAETEQGEQQR 1756
Query: 77 TLMKEQNDQLQDYRVKYLQAQQLVEEQ----RRQXXXXXXXNTRISEQINLEIQRVKLKF 132
L++E+ +LQ Q +Q +E + R + R E+ ++ K +
Sbjct: 1757 QLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRL 1816
Query: 133 QEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLY 192
+ + + + + ++A++ + +AE +A + E E+V + L ++
Sbjct: 1817 EAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEA----ERV--LAEKLAAIG 1870
Query: 193 LVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGD-EKQMALLN-- 249
T + E + ++E R + L+ E+ + D E+++A L
Sbjct: 1871 EATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLE--EQAAQHKADIEERLAQLRKA 1928
Query: 250 -----QRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRT 304
+R L E+ + + ++E ++ + E A A + L+ ++ + R+
Sbjct: 1929 SDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRS 1988
Query: 305 RD----EASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHW 360
++ EA+R Q A E+ R+ + L + A+R Q A +E E LK +
Sbjct: 1989 KEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAAR-QRKAALEEVERLKANVE- 2046
Query: 361 QMKRLTENFEQAQLRILGLQTQVQSLRRTA 390
+ +RL E EQ R L L + R A
Sbjct: 2047 EARRLRERAEQESARQLQLAQEAAQKRLQA 2076
Score = 35.9 bits (79), Expect = 0.26
Identities = 73/350 (20%), Positives = 132/350 (37%), Gaps = 18/350 (5%)
Query: 29 ELEMKFEGLATHTNMLMGSKEQAFEQEVNVRAL----KQCYREAREEIDELRTLMKEQND 84
ELE++ + ++ + SKEQA + R L ++ REA E + + +E
Sbjct: 1970 ELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAAR 2029
Query: 85 QLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPD 144
Q + + + + VEE RR + R Q+ E + +L+ +EK A +
Sbjct: 2030 QRKAALEEVERLKANVEEARRLRERAEQESAR-QLQLAQEAAQKRLQAEEKAHAFA-VQQ 2087
Query: 145 LLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDL 204
+ Q L+ Q AE R A E V R + + +
Sbjct: 2088 KEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQ----ARRQVEEAER 2143
Query: 205 FGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQL-AENNISLK 263
QS E + K E+ R +Q AL ++ + E +
Sbjct: 2144 LKQSAEEQAQARAQ--AQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFA 2201
Query: 264 SEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVR 323
+ R KA V E+ +L+E H+ L EL R + EA+ A R Q E
Sbjct: 2202 EQTLRQKAQV---EQELTTLRLQLEETDHQKNLLDEELQRLKAEATEA-ARQRSQVEEEL 2257
Query: 324 KCLQTTVAELERQLAASRAQ-VSTAEKEREELKNRLHWQMKRLTENFEQA 372
++ + EL + A A+ + ++++ + L + +++ + E+A
Sbjct: 2258 FSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEA 2307
Score = 34.7 bits (76), Expect = 0.60
Identities = 38/160 (23%), Positives = 76/160 (47%), Gaps = 13/160 (8%)
Query: 27 LRELEMKFEGLATHTNMLMGSKE--QAFEQEV---NVRALKQCYREAREEIDELRTLMKE 81
+ ELE + E L +L E Q +QE +AL+Q + ++ + + +++
Sbjct: 2479 IAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQ 2538
Query: 82 QNDQLQD-YRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELA 140
+ +L+ ++ + +AQQL EEQ+RQ R+ + E +R + + +E ++
Sbjct: 2539 EKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASME-EARRRQHEAEEGVRRKQ 2597
Query: 141 PIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREK 180
+L + Q R QQ + +AE N ++L +L E+
Sbjct: 2598 --EELQQLEQQR---RQQEELLAEEN-QRLREQLQLLEEQ 2631
>U53204-1|AAB05427.1| 4574|Homo sapiens plectin protein.
Length = 4574
Score = 55.2 bits (127), Expect = 4e-07
Identities = 72/378 (19%), Positives = 160/378 (42%), Gaps = 14/378 (3%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTL 78
+ +E Q L++ + + L + E+A E V R EE + L+
Sbjct: 2088 KEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQARRQVEEAERLKQS 2147
Query: 79 MKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQE 138
+EQ + + ++ E++ + R + + E+++ K ++ L++
Sbjct: 2148 AEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQ 2207
Query: 139 LAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYL-VTTM 197
A + L +++L++ + + + ++L E A + + L+S+ + + +
Sbjct: 2208 KAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEEL 2267
Query: 198 TLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAE 257
+ + + ++++ I R +KD T L + K ++ E A R+ QLAE
Sbjct: 2268 SKLKARIEAENRALILR-DKDNTQRFLQEEAEK-MKQVAEEAARLSVAAQEAARLRQLAE 2325
Query: 258 NNISLKSEI--ERLKASVIRTEESA-LANEKRLQEKMHECAQLGGELDRTRDEASRALQR 314
+++ + + + LK + +E+ L E L ++ E AQ + R +++ + Q+
Sbjct: 2326 EDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQ--EQARRLQEDKEQMAQQ 2383
Query: 315 AHEQTETVRKCLQT-TVAELERQLAASR-----AQVSTAEKEREELKNRLHWQMKRLTEN 368
E+T+ ++ L+ +LE A R A++S A+ EE R Q + + E
Sbjct: 2384 LAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEK 2443
Query: 369 FEQAQLRILGLQTQVQSL 386
+ +L T VQ+L
Sbjct: 2444 LHRTELATQEKVTLVQTL 2461
Score = 48.0 bits (109), Expect = 6e-05
Identities = 63/332 (18%), Positives = 137/332 (41%), Gaps = 16/332 (4%)
Query: 49 EQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXX 108
EQ Q+ V R EE D + L+ E+ +L+ + + + VEE+
Sbjct: 2202 EQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVR 2261
Query: 109 XXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAE 168
+++ +I E + + L+ ++ Q L+ ++K + A A+
Sbjct: 2262 VQMEELSKLKARIEAENRALILRDKDNTQRF------LQEEAEKMKQVAEEAARLSVAAQ 2315
Query: 169 QLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNS 228
+ AR A E + R L L M QE ++++E+ + K+
Sbjct: 2316 EAARLRQLAEEDLAQQ-RALAEKMLKEKMQAVQEATRLKAEAELLQQQKE-LAQEQARRL 2373
Query: 229 LKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQ 288
+ E+ ++ +E Q + + + + + +E ERLK V + E+ Q
Sbjct: 2374 QEDKEQMAQQLAEETQG--FQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQ 2431
Query: 289 EKMHECAQLGGELDRT----RDEAS--RALQRAHEQTETVRKCLQTTVAELERQLAASRA 342
+ ++G +L RT +++ + + L+ +Q++ + L+ +AELER+ +
Sbjct: 2432 RFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQ 2491
Query: 343 QVSTAEKEREELKNRLHWQMKRLTENFEQAQL 374
+ + + EE++ Q+ + T+ +Q+ L
Sbjct: 2492 EAKLLQLKSEEMQTVQQEQLLQETQALQQSFL 2523
Score = 46.8 bits (106), Expect = 1e-04
Identities = 76/366 (20%), Positives = 145/366 (39%), Gaps = 13/366 (3%)
Query: 29 ELEMKFEGLATHTNMLMGSKEQAFEQ-EVNVRALKQCYREAREEIDELRTLMKEQNDQLQ 87
+L + L T T+ + + + E R +Q E RE + E+ +++Q QL
Sbjct: 1345 DLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQR-QLA 1403
Query: 88 DYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDL-L 146
+ + QA+ E + ++ E+ ++ Q+ K QE+LQ+L + +
Sbjct: 1404 E---AHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEI 1460
Query: 147 KATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFG 206
+A + + A++++ E + +L + L +L Q+
Sbjct: 1461 QAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQ 1520
Query: 207 QSQSEIGRGNKDQTVHVLLHN-SLKPPEKPPERGGDEKQMAL--LNQRISQLAENNISLK 263
+ + R +D++ L K EKQ AL L + Q E L+
Sbjct: 1521 EEAERLRRQVQDESQRKRQAEVELASRVKAETEAAREKQRALQALEELRLQAEEAERRLR 1580
Query: 264 -SEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETV 322
+E+ER + + E + + E LQ K A+ +L+R+ E A+ + E+ E
Sbjct: 1581 QAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAE-- 1638
Query: 323 RKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQLRILGLQTQ 382
R+ Q AE R+ A R K E L+ RL + ++ QA+ + +
Sbjct: 1639 RRAQQQAEAERARE-EAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAE 1697
Query: 383 VQSLRR 388
++ RR
Sbjct: 1698 REARRR 1703
Score = 46.4 bits (105), Expect = 2e-04
Identities = 74/345 (21%), Positives = 147/345 (42%), Gaps = 20/345 (5%)
Query: 21 RETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRAL-KQCYREAREEIDELRTLM 79
+E K++++ + L+ ++ A E RAL ++ +E + + E L
Sbjct: 2294 QEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLK 2353
Query: 80 KEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQEL 139
E Q + QA++L E++ + + E QR +L+ + + L
Sbjct: 2354 AEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQR-QLEMSAEAERL 2412
Query: 140 A-PIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMT 198
+ ++ +A +DAQ+ + AE E+L R +EKV + +L + +
Sbjct: 2413 KLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLV----QTLEIQRQQS 2468
Query: 199 LTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQ--LA 256
+ ++ +E+ R K++ LK E + ++Q+ Q + Q L+
Sbjct: 2469 DHDAERLREAIAELER-EKEKLQQEAKLLQLKSEEMQTVQ---QEQLLQETQALQQSFLS 2524
Query: 257 ENNISLKSE--IERLKASVIRTEESALANEKRL-QEKMHECAQLGGELDRTRDEASRALQ 313
E + L+ E IE+ KA + + + +A ++L +E+ + Q+ E R A +
Sbjct: 2525 EKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARR 2584
Query: 314 RAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRL 358
R HE E VR+ Q + +LE+Q R Q +E + L+ +L
Sbjct: 2585 RQHEAEEGVRR-KQEELQQLEQQ---RRQQEELLAEENQRLREQL 2625
Score = 46.0 bits (104), Expect = 2e-04
Identities = 80/375 (21%), Positives = 147/375 (39%), Gaps = 32/375 (8%)
Query: 17 RCQHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELR 76
R + R Q R+L++ E A + K AF + + L+Q ++ + +D+LR
Sbjct: 2050 RLRERAEQESARQLQLAQE--AAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLR 2107
Query: 77 TLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKL 136
+ ++ +QA++ + RRQ E +R+K +E+
Sbjct: 2108 GEAEAARRAAEEAEEARVQAEREAAQARRQVE---------------EAERLKQSAEEQA 2152
Query: 137 QELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTT 196
Q A +A +L+ + +A AEQ A A + + + L
Sbjct: 2153 QARAQ----AQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQK 2208
Query: 197 MTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLA 256
+ QE + Q E K+ L + E +R E+++ + ++ +L+
Sbjct: 2209 AQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELS 2268
Query: 257 ENNISLKSEIE-RLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRA 315
+ LK+ IE +A ++R +++ + EKM + A+ L EA+R Q A
Sbjct: 2269 K----LKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLA 2324
Query: 316 HEQTETVRKCLQTTVAELERQLAASRAQVSTAEKE-REELKNRLHWQMKRLTENFEQAQL 374
E R + + E+ A A AE E ++ K Q +RL E+ EQ
Sbjct: 2325 EEDLAQQRALAEKMLK--EKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQ 2382
Query: 375 RILGLQTQVQSLRRT 389
+ L + Q +RT
Sbjct: 2383 Q---LAEETQGFQRT 2394
Score = 38.3 bits (85), Expect = 0.049
Identities = 89/407 (21%), Positives = 148/407 (36%), Gaps = 45/407 (11%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKEQA---FEQEVNVRALKQCYRE-----ARE 70
Q R Q +L++L E + E++ E+E+ V L+ E A
Sbjct: 1441 QKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEG 1500
Query: 71 EIDELRTLMKE---QNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQR 127
E+ LR +E Q Q Q+ + + Q +++RQ + + E QR
Sbjct: 1501 ELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAETEAAREKQR 1560
Query: 128 VKLKFQE-KLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAE-QLARELNCAREKVVHIF 185
+E +LQ L +A R + Q A A+ +AE +L + EK +
Sbjct: 1561 ALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLE 1620
Query: 186 RYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKD--------------------QTVHVLL 225
R L ++ + + Q Q+E R ++ Q V
Sbjct: 1621 RSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQ 1680
Query: 226 HNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEK 285
SL E ++ E++ + Q + E+E+ + T + LA E+
Sbjct: 1681 QKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQ 1740
Query: 286 RLQEKMHECAQ-------LGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLA 338
L E Q L EL R + EA+ A Q+ E + K AE+E LA
Sbjct: 1741 ELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVR----AEMEVLLA 1796
Query: 339 ASRAQVSTAEKEREELKNRLHWQMKRLTENFEQ-AQLRILGLQTQVQ 384
+ + E+ K RL + R E E+ A+LR L + + Q
Sbjct: 1797 SKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQ 1843
Score = 38.3 bits (85), Expect = 0.049
Identities = 31/134 (23%), Positives = 57/134 (42%), Gaps = 3/134 (2%)
Query: 47 SKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQ 106
+K Q +E R +Q +E + + + + Q++ + R K + QQL +++R+Q
Sbjct: 2552 AKAQQLREEQQ-RQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQ 2610
Query: 107 XXXXXXXNTRISEQINL--EIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAE 164
N R+ EQ+ L E R L E++ D A+A E
Sbjct: 2611 EELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPE 2670
Query: 165 HNAEQLARELNCAR 178
H+ + L R+++ R
Sbjct: 2671 HSFDGLRRKVSAQR 2684
Score = 36.3 bits (80), Expect = 0.20
Identities = 75/390 (19%), Positives = 157/390 (40%), Gaps = 30/390 (7%)
Query: 17 RCQHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELR 76
R + + + +R+ E+ + L + G+ +Q E + L R E+ ++ R
Sbjct: 1701 RRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRL----RAETEQGEQQR 1756
Query: 77 TLMKEQNDQLQDYRVKYLQAQQLVEEQ----RRQXXXXXXXNTRISEQINLEIQRVKLKF 132
L++E+ +LQ Q +Q +E + R + R E+ ++ K +
Sbjct: 1757 QLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRL 1816
Query: 133 QEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLY 192
+ + + + + ++A++ + +AE +A + E E+V + L ++
Sbjct: 1817 EAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEA----ERV--LAEKLAAIG 1870
Query: 193 LVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGD-EKQMALLN-- 249
T + E + ++E R + L+ E+ + D E+++A L
Sbjct: 1871 EATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLE--EQAAQHKADIEERLAQLRKA 1928
Query: 250 -----QRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRT 304
+R L E+ + + ++E ++ + E A A + L+ ++ + R+
Sbjct: 1929 SDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRS 1988
Query: 305 RD----EASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHW 360
++ EA+R Q A E+ R+ + L + A+R Q A +E E LK +
Sbjct: 1989 KEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAAR-QRKAALEEVERLKANVE- 2046
Query: 361 QMKRLTENFEQAQLRILGLQTQVQSLRRTA 390
+ +RL E EQ R L L + R A
Sbjct: 2047 EARRLRERAEQESARQLQLAQEAAQKRLQA 2076
Score = 35.9 bits (79), Expect = 0.26
Identities = 73/350 (20%), Positives = 132/350 (37%), Gaps = 18/350 (5%)
Query: 29 ELEMKFEGLATHTNMLMGSKEQAFEQEVNVRAL----KQCYREAREEIDELRTLMKEQND 84
ELE++ + ++ + SKEQA + R L ++ REA E + + +E
Sbjct: 1970 ELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAAR 2029
Query: 85 QLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPD 144
Q + + + + VEE RR + R Q+ E + +L+ +EK A +
Sbjct: 2030 QRKAALEEVERLKANVEEARRLRERAEQESAR-QLQLAQEAAQKRLQAEEKAHAFA-VQQ 2087
Query: 145 LLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDL 204
+ Q L+ Q AE R A E V R + + +
Sbjct: 2088 KEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQ----ARRQVEEAER 2143
Query: 205 FGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQL-AENNISLK 263
QS E + K E+ R +Q AL ++ + E +
Sbjct: 2144 LKQSAEEQAQARAQ--AQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFA 2201
Query: 264 SEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVR 323
+ R KA V E+ +L+E H+ L EL R + EA+ A R Q E
Sbjct: 2202 EQTLRQKAQV---EQELTTLRLQLEETDHQKNLLDEELQRLKAEATEA-ARQRSQVEEEL 2257
Query: 324 KCLQTTVAELERQLAASRAQ-VSTAEKEREELKNRLHWQMKRLTENFEQA 372
++ + EL + A A+ + ++++ + L + +++ + E+A
Sbjct: 2258 FSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEA 2307
Score = 34.7 bits (76), Expect = 0.60
Identities = 38/160 (23%), Positives = 76/160 (47%), Gaps = 13/160 (8%)
Query: 27 LRELEMKFEGLATHTNMLMGSKE--QAFEQEV---NVRALKQCYREAREEIDELRTLMKE 81
+ ELE + E L +L E Q +QE +AL+Q + ++ + + +++
Sbjct: 2479 IAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQ 2538
Query: 82 QNDQLQD-YRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELA 140
+ +L+ ++ + +AQQL EEQ+RQ R+ + E +R + + +E ++
Sbjct: 2539 EKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASME-EARRRQHEAEEGVRRKQ 2597
Query: 141 PIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREK 180
+L + Q R QQ + +AE N ++L +L E+
Sbjct: 2598 --EELQQLEQQR---RQQEELLAEEN-QRLREQLQLLEEQ 2631
>M31013-1|AAA36349.1| 1247|Homo sapiens protein ( Human nonmuscle
myosin heavy chain (NMHC) mRNA, 3' end. ).
Length = 1247
Score = 55.2 bits (127), Expect = 4e-07
Identities = 72/390 (18%), Positives = 172/390 (44%), Gaps = 29/390 (7%)
Query: 22 ETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKE 81
E + ELE + T LM SK+ + +V L++ R ++++E++T ++E
Sbjct: 774 EAMEQKAELERLNKQFRTEMEDLMSSKDDVGK---SVHELEKSKRALEQQVEEMKTQLEE 830
Query: 82 QNDQLQ---DYRVKY-LQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQ 137
D+LQ D +++ + Q + + R + +Q+ +++ ++ + +++ +
Sbjct: 831 LEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERK 890
Query: 138 ELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTM 197
+ + K +M LKD + A N ++ ++L + ++ R L
Sbjct: 891 QRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMREL------DDT 944
Query: 198 TLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAE 257
++E++ Q++ + + + L L E+ +R +++ L ++ + +
Sbjct: 945 RASREEILAQAKENEKKLKSMEAEMIQLQEELAAAER-AKRQAQQERDELADEIANSSGK 1003
Query: 258 NNISLKSEIERLKASVIRTEE--------SALANEKRLQEKMHECAQLGGELDRTRDEAS 309
++L+ E RL+A + + EE + L N+ RL++ + Q+ +L+ R A
Sbjct: 1004 GALALE-EKRRLEARIAQLEEELEEEQGNTELIND-RLKKANLQIDQINADLNLERGHAQ 1061
Query: 310 RALQRAHEQTETVRKCLQTTVAELERQLAAS-RAQVSTAEKEREELKNRLHWQMKR---L 365
+ + A +Q E K L+ + E+E + + +A ++ E + +L+ +L + K
Sbjct: 1062 KN-ENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAA 1120
Query: 366 TENFEQAQLRILGLQTQVQSLRRTASSTGD 395
+ + + ++ + QV RR A D
Sbjct: 1121 CKQVRRTEKKLKDVLLQVDDERRNAEQYKD 1150
Score = 48.4 bits (110), Expect = 5e-05
Identities = 80/367 (21%), Positives = 154/367 (41%), Gaps = 50/367 (13%)
Query: 26 KLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQ 85
K+RE ++ E L + Q +++ ++ Q E E +ELR + + +
Sbjct: 142 KVREKQLAAENRLMEMETL---QSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQE 198
Query: 86 LQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDL 145
L++ L+A+ EE+R Q Q N++ +L+ +E ++ + +
Sbjct: 199 LEEI-CHDLEARVEEEEERYQHLQAEKKKM----QQNIQELEEQLEEEESARQKLQLEKV 253
Query: 146 LKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLF 205
T+ +LK ++ Q I E +LA+E +++ T LT+E+
Sbjct: 254 --TTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEF-----------TTNLTEEEEK 300
Query: 206 GQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSE 265
+S +++ NK + + L L+ EK +R EK L + L++ L+++
Sbjct: 301 SKSLAKLK--NKHEAMITDLEERLRREEK--QRQELEKTRRKLEGDSTDLSDQIAELQAQ 356
Query: 266 IERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKC 325
I LK + + EE A R++E E AQ L + R+
Sbjct: 357 IAELKMQLAKKEEELQAALARVEE---EAAQKNMALKKIRE------------------- 394
Query: 326 LQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQ--AQLRILGLQTQ- 382
L++ ++EL+ L + RA + AEK++ +L L L + + AQ + + Q
Sbjct: 395 LESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQE 454
Query: 383 VQSLRRT 389
V L++T
Sbjct: 455 VNILKKT 461
Score = 43.2 bits (97), Expect = 0.002
Identities = 69/367 (18%), Positives = 145/367 (39%), Gaps = 27/367 (7%)
Query: 19 QHRETQNKLRELEMKF-EGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRT 77
+ ++ + +L+EL++KF EG T + ++ + +V + + ++ + +L
Sbjct: 532 KRKKVEAQLQELQVKFNEGERVRTELA----DKVTKLQVELDNVTGLLSQSDSKSSKLTK 587
Query: 78 LMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQ 137
QLQD Q+L++E+ RQ ++ ++ N ++++ + +E
Sbjct: 588 DFSALESQLQD-------TQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEEAKH 640
Query: 138 ELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLY--LVT 195
L L A +K + AE++ R+L E + + Y L
Sbjct: 641 NLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEK 700
Query: 196 TMTLTQE-------DLFGQSQSEIGRGNKDQTVHVLLHN----SLKPPEKPPERGGDEKQ 244
T T Q+ DL Q QS K + LL S K E+ + ++
Sbjct: 701 TKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEARE 760
Query: 245 MALLNQRISQLAENNISLKSEIERLKASVIRTE-ESALANEKRLQEKMHECAQLGGELDR 303
+++ E + K+E+ERL RTE E ++++ + + +HE + L++
Sbjct: 761 KETKALSLARALEEAMEQKAELERLNKQ-FRTEMEDLMSSKDDVGKSVHELEKSKRALEQ 819
Query: 304 TRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMK 363
+E L+ ++ + L+ A + +++ EE K +L Q++
Sbjct: 820 QVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVR 879
Query: 364 RLTENFE 370
+ E
Sbjct: 880 EMEAELE 886
Score = 41.9 bits (94), Expect = 0.004
Identities = 71/319 (22%), Positives = 131/319 (41%), Gaps = 36/319 (11%)
Query: 119 EQINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAR 178
E+ ++++ +L + +L E+ + L A +++L++ QA+ AE+L L +
Sbjct: 137 EEELVKVREKQLAAENRLMEMETLQSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKK 196
Query: 179 EKVVHIF------------RYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLH 226
+++ I RY + M ++L Q + E K Q V
Sbjct: 197 QELEEICHDLEARVEEEEERYQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTE 256
Query: 227 NSLKPPEKPPERGGDE-----KQMALLNQRISQLAENNISLKSEIERLKA-SVIRTEESA 280
LK E+ D+ K+ LL RI++ N L E E+ K+ + ++ + A
Sbjct: 257 AKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTN---LTEEEEKSKSLAKLKNKHEA 313
Query: 281 LANEKRLQEKMHECAQLGGELDRTR-----DEASRALQRAHEQTETVRKCLQTTVAELER 335
+ + L+E++ + EL++TR D + Q A Q + +Q E E
Sbjct: 314 MITD--LEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEEL 371
Query: 336 QLAASRAQVSTAEKEREELKNR-LHWQMKRLTENFE-------QAQLRILGLQTQVQSLR 387
Q A +R + A+K K R L Q+ L E+ E +A+ + L ++++L+
Sbjct: 372 QAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALK 431
Query: 388 RTASSTGDGDGENQECTCK 406
T D QE K
Sbjct: 432 TELEDTLDSTAAQQELRSK 450
Score = 39.5 bits (88), Expect = 0.021
Identities = 79/364 (21%), Positives = 150/364 (41%), Gaps = 23/364 (6%)
Query: 24 QNKLRELE-MKFEGLATHTNM---LMGSKEQAFEQEVNVRALKQCYREAREEI-DELRTL 78
+N+L E+E ++ + +A + L E E E +RA ++ EEI +L
Sbjct: 151 ENRLMEMETLQSQLMAEKLQLQEQLQAETELCAEAE-ELRARLTAKKQELEEICHDLEAR 209
Query: 79 MKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRIS-EQINLEIQRVKLKFQEKLQ 137
++E+ ++ Q + + + QQ ++E Q ++ E++ E + KL+ ++ +
Sbjct: 210 VEEEEERYQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIIL 269
Query: 138 E--LAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVT 195
E + K + R+ + E ++ LA+ N + + L
Sbjct: 270 EDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQR 329
Query: 196 T-MTLTQEDLFGQSQ--SEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRI 252
+ T+ L G S S+ + Q + + + K E E++ A N +
Sbjct: 330 QELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMAL 389
Query: 253 SQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDE--ASR 310
++ E L+S+I L+ + S EK+ ++ E L EL+ T D A +
Sbjct: 390 KKIRE----LESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQ 445
Query: 311 ALQRAHEQ-TETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENF 369
L+ EQ ++K L+ E Q+ R + S A EEL +L Q KR+ N
Sbjct: 446 ELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAV---EELAEQLE-QTKRVKANL 501
Query: 370 EQAQ 373
E+A+
Sbjct: 502 EKAK 505
Score = 36.7 bits (81), Expect = 0.15
Identities = 69/336 (20%), Positives = 131/336 (38%), Gaps = 32/336 (9%)
Query: 28 RELEMKFEGLATHTNMLMGSKEQAFEQEVNVRA-LKQCYRE---AREEIDELRTLMKEQN 83
++LEM + L H + ++++A +Q ++A +K C RE R +E+ KE
Sbjct: 900 KKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENE 959
Query: 84 DQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIP 143
+L+ + +Q Q+ + R ++++I + L +EK
Sbjct: 960 KKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEK-------- 1011
Query: 144 DLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQED 203
R +A+ AQ E EQ EL R K ++ + L Q++
Sbjct: 1012 --------RRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINADLNLERGHAQKN 1063
Query: 204 LFGQSQSEIGRGNKDQTVHVL-LHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISL 262
+ Q E R NK+ V + + ++K K + L +I+QL E +
Sbjct: 1064 ENARQQLE--RQNKELKVKLQEMEGTVKSKYKA--------SITALEAKIAQLEEQLDNE 1113
Query: 263 KSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETV 322
E + V RTE+ ++ ++ Q + D+ + L+R E+ E
Sbjct: 1114 TKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQ-LKRQLEEAEEE 1172
Query: 323 RKCLQTTVAELERQLAASRAQVSTAEKEREELKNRL 358
+ + +L+R+L + +E LKN+L
Sbjct: 1173 AQRANASRRKLQRELEDATETADAMNREVSSLKNKL 1208
Score = 33.9 bits (74), Expect = 1.1
Identities = 76/360 (21%), Positives = 153/360 (42%), Gaps = 31/360 (8%)
Query: 48 KEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQX 107
+E+A E ++ ++Q + +A EE + EQ +Q + + +A+Q +E +R +
Sbjct: 463 EEEAKTHEAQIQEMRQKHSQAVEE-------LAEQLEQTKRVKANLEKAKQTLENERGE- 514
Query: 108 XXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNA 167
++ Q + + + K + +LQEL + + + L D + N
Sbjct: 515 ---LANEVKVLLQGGRDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNV 571
Query: 168 EQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHN 227
L + + K+ F L S L T L QE +++ ++ K + V ++
Sbjct: 572 TGLLSQSDSKSSKLTKDFSALES-QLQDTQELLQE----ENRQKLSLSTKLKQVEDEKNS 626
Query: 228 SLKPPEKPPERGGD--EKQMALLNQRISQL---AENNISLKSEIERLKASVIRTEES-AL 281
+ E+ E EKQ+A L+ +++ + E+++ E +K + + E +
Sbjct: 627 FREQLEEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQ 686
Query: 282 ANEKRL--QEKMHEC-AQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLA 338
+E+++ +K+ + +L ELD + Q A E +K +AE E+ ++
Sbjct: 687 RHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSAC-NLEKKQKKFDQLLAE-EKTIS 744
Query: 339 ASRAQV-STAEKEREELKNRLHWQMKRLTENFEQ-AQLRILGLQ--TQVQSLRRTASSTG 394
A A+ AE E E + + + L E EQ A+L L Q T+++ L + G
Sbjct: 745 AKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVG 804
>L40157-1|AAA79121.1| 1410|Homo sapiens endosome-associated protein
protein.
Length = 1410
Score = 55.2 bits (127), Expect = 4e-07
Identities = 74/385 (19%), Positives = 161/385 (41%), Gaps = 21/385 (5%)
Query: 24 QNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQN 83
Q+K +EL L T L +E + E +++ K+ Y ++ +EL +K+
Sbjct: 677 QDKHQELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQIKKLE 736
Query: 84 DQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLE---IQRVKLKFQEKLQELA 140
+ + QA Q +++QR+ T +S+Q+ +E + +L Q+K + L
Sbjct: 737 ADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKSEALE 796
Query: 141 PIPD-LLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRY-LYSLYLVTTMT 198
I L K + + Q + +++ Q N + V + + + L+T ++
Sbjct: 797 SIKQKLTKQEEEKQILKQDFETLSQETKIQHEELNNRIQTTVTELQKVKMEKEALMTELS 856
Query: 199 LTQE------DLFGQSQSEIGRGNKDQTVHVL-LHNSLK--PPEKPPERGGDEKQMALLN 249
++ D S+SE + N+ +L L + K + + K+ L
Sbjct: 857 TVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKELKHQLQVQMENTLKEQKELK 916
Query: 250 QRISQLAENNISLKSEIERLKASVIRTEESALANEK---RLQEKMHECAQLGGELDRTRD 306
+ + + E + LK E+ ++ +I+ + + NEK +LQ ++E Q + + +
Sbjct: 917 KSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQGNINELKQSSEQKKKQIE 976
Query: 307 EASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLT 366
L+ A Q + LQ + + ++LAA + ++S + E+ + K+L
Sbjct: 977 ALQGELKIAVLQKTELENKLQQQLTQAAQELAAEKEKISVLQNNYEKSQE----TFKQLQ 1032
Query: 367 ENFEQAQLRILGLQTQVQSLRRTAS 391
+F + +L + ++S+ S
Sbjct: 1033 SDFYGRESELLATRQDLKSVEEKLS 1057
Score = 51.6 bits (118), Expect = 5e-06
Identities = 74/397 (18%), Positives = 169/397 (42%), Gaps = 33/397 (8%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQC----YREAREEIDE 74
Q + Q KL LE + + T++ L ++ +Q +AL+Q REA+ ++++
Sbjct: 454 QVADLQLKLSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQSTTAKLREAQNDLEQ 513
Query: 75 LRTLMKEQNDQLQDYRVKYLQAQQ---LVEEQRRQXXXXXXX--------------NTRI 117
+ + E++ ++Q+ ++++ L+E++R N +
Sbjct: 514 VLRQIGEKDQKIQNLEALLQKSKENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHTL 573
Query: 118 SEQINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCA 177
+++ + VK + + Q + D ++ + L+ AQ E + +L +LN +
Sbjct: 574 QDEVTQLTENVKNQSESHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQLNES 633
Query: 178 REKVVHI---FRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEK 234
+EKV + + L L T + Q+ + + N Q H L+ ++
Sbjct: 634 KEKVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHLDTAQ-NALQDKHQELNKITTQLDQ 692
Query: 235 PPERGGDEKQ-MALLNQRISQLAENNISLKSEIERLKASVIRTEESAL---ANEKRLQEK 290
+ D+++ + L + + E +SL+ + E L+ + + E +L A++++ +
Sbjct: 693 VTAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQIKKLEADSLEVKASKEQALQD 752
Query: 291 MHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKE 350
+ + QL +L+ E S+ L+ E + R LQ LE + + +++ E+E
Sbjct: 753 LQQQRQLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKSEALE----SIKQKLTKQEEE 808
Query: 351 REELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLR 387
++ LK + E+ RI T++Q ++
Sbjct: 809 KQILKQDFETLSQETKIQHEELNNRIQTTVTELQKVK 845
Score = 47.2 bits (107), Expect = 1e-04
Identities = 72/361 (19%), Positives = 139/361 (38%), Gaps = 16/361 (4%)
Query: 22 ETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQ-EVNVRALKQCYREAREEIDELRTLMK 80
+ Q K L+ + L + S +QA E V+ K R A++ + L T +
Sbjct: 565 QLQEKNHTLQDEVTQLTENVKNQSESHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVN 624
Query: 81 EQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELA 140
E N QL + + K Q ++ + T + + + Q+K QEL
Sbjct: 625 ELNSQLNESKEKVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHLDTAQNALQDKHQELN 684
Query: 141 PIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLT 200
I L +L+D Q+ + E + ++ + +K + + L +
Sbjct: 685 KITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQIKKLEADSLEVKA 744
Query: 201 QEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEK----PPERGGDEKQMAL--LNQRISQ 254
++ Q + + N D + + EK +K AL + Q++++
Sbjct: 745 SKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKSEALESIKQKLTK 804
Query: 255 LAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQR 314
E LK + E L + + L N R+Q + E ++ E + E L
Sbjct: 805 QEEEKQILKQDFETLSQET-KIQHEELNN--RIQTTVTELQKVKMEKEALMTE----LST 857
Query: 315 AHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQL 374
++ V L+ + +E E++ +A + EK +ELK++L QM+ + EQ +L
Sbjct: 858 VKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKELKHQLQVQMENTLK--EQKEL 915
Query: 375 R 375
+
Sbjct: 916 K 916
Score = 46.8 bits (106), Expect = 1e-04
Identities = 67/361 (18%), Positives = 152/361 (42%), Gaps = 25/361 (6%)
Query: 48 KEQAFEQEVNVRALKQCYREAREEIDE-------LRTLMKEQNDQLQDYRVKYLQAQQLV 100
KE+ E E + LK +++ +++ +E L++ + + + +L + + +A +
Sbjct: 378 KEELSEVETKYQHLKAEFKQLQQQREEKEQHGLQLQSEINQLHSKLLETERQLGEAHGRL 437
Query: 101 EEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQ 160
+EQR+ + + L++ R++ + +EK+ + L T+ + ++ Q Q
Sbjct: 438 KEQRQLSSEKLMDKEQQVADLQLKLSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQ 497
Query: 161 AI-------AEHNAEQLARELNCAREKVVHIFRYLY-SLYLVTTMTLTQEDLFGQSQSEI 212
A+++ EQ+ R++ +K+ ++ L S ++ + +EDL+ + Q+
Sbjct: 498 QSTTAKLREAQNDLEQVLRQIGEKDQKIQNLEALLQKSKENISLLEKEREDLYAKIQA-- 555
Query: 213 GRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKAS 272
G G + N E + Q Q L + K+ + +
Sbjct: 556 GEGETAVLNQLQEKNHTLQDEVTQLTENVKNQSESHKQAQENLHDQVQEQKAHLRAAQDR 615
Query: 273 VIRTEESALANEKRLQEKMHECAQLGGELDRTRD-----EASRALQRAHEQT--ETVRKC 325
V+ E S +L E + +QL ++ + EA++ QRA Q +T +
Sbjct: 616 VLSLETSVNELNSQLNESKEKVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHLDTAQNA 675
Query: 326 LQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQLRILGLQTQVQS 385
LQ EL + + QV+ ++++E ++L +K E + + + L+ Q++
Sbjct: 676 LQDKHQELNK-ITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQIKK 734
Query: 386 L 386
L
Sbjct: 735 L 735
Score = 44.4 bits (100), Expect = 7e-04
Identities = 53/270 (19%), Positives = 108/270 (40%), Gaps = 8/270 (2%)
Query: 120 QINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCARE 179
+I++E+ Q+ +EL+ + + + K QQ + E + QL E+N
Sbjct: 362 RIHVELSEKGEATQKLKEELSEVETKYQHLKAEFKQLQQQREEKEQHGLQLQSEINQLHS 421
Query: 180 KVVHIFRYLYSLY--LVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPE 237
K++ R L + L L+ E L + Q K + L + +
Sbjct: 422 KLLETERQLGEAHGRLKEQRQLSSEKLMDKEQQVADLQLKLSRLEEQLKEKVTNSTELQH 481
Query: 238 RGGDEKQMALLNQRISQLAENNI-SLKSEIERLKASVIRTEESALANEKRLQEKMHECAQ 296
+ KQ Q + Q + ++++E++ I ++ + N + L +K E
Sbjct: 482 QLDKTKQQHQEQQALQQSTTAKLREAQNDLEQVLRQ-IGEKDQKIQNLEALLQKSKENIS 540
Query: 297 LGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKN 356
L L++ R++ +Q +T + + LQ L+ ++ V + ++ +
Sbjct: 541 L---LEKEREDLYAKIQAGEGETAVLNQ-LQEKNHTLQDEVTQLTENVKNQSESHKQAQE 596
Query: 357 RLHWQMKRLTENFEQAQLRILGLQTQVQSL 386
LH Q++ + AQ R+L L+T V L
Sbjct: 597 NLHDQVQEQKAHLRAAQDRVLSLETSVNEL 626
Score = 43.2 bits (97), Expect = 0.002
Identities = 77/340 (22%), Positives = 144/340 (42%), Gaps = 57/340 (16%)
Query: 22 ETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQ----EVNVRALKQCYREAREEIDELRT 77
E L++ E K +GL T ++ + S EQ E+ N++ +K + + + +L T
Sbjct: 114 EKYQGLQQQEAKPDGLVTDSSAELQSLEQQLEEAQTENFNIKQMKDLFEQ---KAAQLAT 170
Query: 78 LMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQ 137
++ D + KY + + L E ++ TR++E++N E + Q+
Sbjct: 171 -------EIADIKSKYDEERSLREAAEQKV-------TRLTEELNKEATVI----QDLKT 212
Query: 138 ELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTM 197
EL P + ++ K+ Q Q + ++ + RE EK+ + S Y +
Sbjct: 213 ELLQRPGIEDVAVLK-KELVQVQTLMDNMTLERERE----SEKLKDESKKFESQYASSEA 267
Query: 198 TLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAE 257
T++Q +SE+ +G ++ V+V LK + L Q+ L E
Sbjct: 268 TISQ------LRSELSKGPQEVRVYVQELQKLK------------SSVNELTQKNQTLTE 309
Query: 258 NNISLKSEIERLKASVIRTEESALANEKRLQEKMH----ECAQLGGELDRTRDEASRALQ 313
N LK E + K EES ++K +Q +H +C QL L + R
Sbjct: 310 N--LLKKEQDYTKLEEKHNEESV--SKKNIQATLHQKDLDCQQLQSRLSASETSLHRIHV 365
Query: 314 RAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREE 353
E+ E +K L+ ++E+E + +A+ +++REE
Sbjct: 366 ELSEKGEATQK-LKEELSEVETKYQHLKAEFKQLQQQREE 404
Score = 34.7 bits (76), Expect = 0.60
Identities = 67/371 (18%), Positives = 154/371 (41%), Gaps = 36/371 (9%)
Query: 48 KEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQX 107
KEQ E + ++ K+ + + E++ ++ + + + L+ + Q Q + E ++
Sbjct: 910 KEQK-ELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQGNINELKQSS 968
Query: 108 XXXXXXNTRISEQINLEIQRVKLKFQEKLQE-LAPIPDLLKATQMRLKDAQQAQAIAEHN 166
+ ++ + + + K + + KLQ+ L L A + ++ Q ++
Sbjct: 969 EQKKKQIEALQGELKIAVLQ-KTELENKLQQQLTQAAQELAAEKEKISVLQNNYEKSQET 1027
Query: 167 AEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKD----QTVH 222
+QL + +++ + L S+ ++L QEDL ++++IG NK +T
Sbjct: 1028 FKQLQSDFYGRESELLATRQDLKSVE--EKLSLAQEDLIS-NRNQIGNQNKLIQELKTAK 1084
Query: 223 VLLH-NSLKPPEKPPER-----------GGDEKQMALLNQRISQLAENNISLKSEIERLK 270
L +S K ++ ER EK++ +++++ E + EI +L
Sbjct: 1085 ATLEQDSAKKEQQLQERCKALQDIQKEKSLKEKELVNEKSKLAEIEEIKCRQEKEITKLN 1144
Query: 271 ASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTV 330
+ + ++ L++ Q EL D A+++ + ++ ++
Sbjct: 1145 EELKSHKLESIKEITNLKDAKQLLIQQKLELQGKADSLKAAVEQEKRNQQILKDQVKKEE 1204
Query: 331 AELERQLAASRAQVSTAEKER-------EELKNRLHWQMKRLTEN-------FEQAQLRI 376
EL+++ A++ + KE+ EE + +L Q+ L EN ++ +Q R+
Sbjct: 1205 EELKKEFIEKEAKLHSEIKEKEVGMKKHEENEAKLTMQITALNENLGTVKKEWQSSQRRV 1264
Query: 377 LGLQTQVQSLR 387
L+ Q LR
Sbjct: 1265 SELEKQTDDLR 1275
Score = 32.7 bits (71), Expect = 2.4
Identities = 32/129 (24%), Positives = 56/129 (43%), Gaps = 9/129 (6%)
Query: 262 LKSEIERLKASVIRTEESALANE-KRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTE 320
L+ E++ L+AS+ EE + E K+ EK Q + D ++S LQ +Q E
Sbjct: 88 LRQEVQDLQASL--KEEKWYSEELKKELEKYQGLQQQEAKPDGLVTDSSAELQSLEQQLE 145
Query: 321 TVR------KCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQL 374
+ K ++ + QLA A + + E L+ ++ RLTE +
Sbjct: 146 EAQTENFNIKQMKDLFEQKAAQLATEIADIKSKYDEERSLREAAEQKVTRLTEELNKEAT 205
Query: 375 RILGLQTQV 383
I L+T++
Sbjct: 206 VIQDLKTEL 214
Score = 30.7 bits (66), Expect = 9.8
Identities = 25/143 (17%), Positives = 68/143 (47%), Gaps = 5/143 (3%)
Query: 244 QMALLNQRISQLAENNISLKS--EIERLKASVIRTEESALANEKRLQEKMHECAQLGGEL 301
++ L Q++ + N ++K ++ KA+ + TE + + ++ + + E A+ ++
Sbjct: 136 ELQSLEQQLEEAQTENFNIKQMKDLFEQKAAQLATEIADIKSKYDEERSLREAAEQ--KV 193
Query: 302 DRTRDEASRALQRAHE-QTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHW 360
R +E ++ + +TE +++ VA L+++L + + ERE +L
Sbjct: 194 TRLTEELNKEATVIQDLKTELLQRPGIEDVAVLKKELVQVQTLMDNMTLERERESEKLKD 253
Query: 361 QMKRLTENFEQAQLRILGLQTQV 383
+ K+ + ++ I L++++
Sbjct: 254 ESKKFESQYASSEATISQLRSEL 276
>D10667-1|BAA36971.1| 1052|Homo sapiens smooth muscle myosin heavy
chain protein.
Length = 1052
Score = 55.2 bits (127), Expect = 4e-07
Identities = 77/370 (20%), Positives = 153/370 (41%), Gaps = 36/370 (9%)
Query: 29 ELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQ- 87
ELE + L L+ SK+ + NV L++ R +++E++T ++E D+LQ
Sbjct: 615 ELERTNKMLKAEMEDLVSSKDDVGK---NVHELEKSKRALETQMEEMKTQLEELEDELQA 671
Query: 88 --DYRVKY-LQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPD 144
D +++ + Q L + R N Q+ ++ + + +++ E A
Sbjct: 672 SEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERNERALAAA 731
Query: 145 LLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDL 204
K + LKD + A E+ ++L + ++ R L +++++
Sbjct: 732 AKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDA------RASRDEI 785
Query: 205 FGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKS 264
F ++ + + + L L E+ ++ EK+ L + S L+ N +L+
Sbjct: 786 FATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKE-ELAEELASSLSGRN-ALQD 843
Query: 265 EIERLKASVIRTEE-------SALANEKRLQEKMHECAQLGGELDRTR------DEASRA 311
E RL+A + + EE + A R+++ + QL EL R + A +
Sbjct: 844 EKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQ 903
Query: 312 LQRA--------HEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMK 363
L+R HE V+ ++T+A LE ++A QV +E++ L + K
Sbjct: 904 LERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDK 963
Query: 364 RLTENFEQAQ 373
+L E Q +
Sbjct: 964 KLKEILLQVE 973
Score = 43.2 bits (97), Expect = 0.002
Identities = 78/398 (19%), Positives = 161/398 (40%), Gaps = 29/398 (7%)
Query: 22 ETQNKLRELEMKFEGLATHT----NMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRT 77
E + R LE + E + T + L S++ EVN++ALK + + DE
Sbjct: 643 ELEKSKRALETQMEEMKTQLEELEDELQASEDAKLRLEVNMQALKGQFERDLQARDEQN- 701
Query: 78 LMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQI-NLEIQRVK-LKFQEK 135
+E+ QLQ +Y + +E++R + ++ + +LE+Q +K +E+
Sbjct: 702 --EEKRRQLQRQLHEY---ETELEDERNERALAAAAKKKLEGDLKDLELQADSAIKGREE 756
Query: 136 -LQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLV 194
+++L + +K Q L+DA+ ++ A++ ++ ++ + L +
Sbjct: 757 AIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERA 816
Query: 195 TTMT-LTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRIS 253
L +E+L + S + N Q L + E+ E ++ M ++ R+
Sbjct: 817 RKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEE--EQGNMEAMSDRVR 874
Query: 254 QLAENNISLKSEIERLKASVIRTEESALANE---KRLQEKMHEC-AQLGGELDRTRDEAS 309
+ + L +E+ +++ + E + E K L+ K+HE + + T
Sbjct: 875 KATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALE 934
Query: 310 RALQRAHEQTETVRKCLQTTVAEL---ERQLAASRAQVSTAEKEREELKNRLHW------ 360
+ + EQ E + Q L +++L QV K E+ K +
Sbjct: 935 AKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVK 994
Query: 361 QMKRLTENFEQAQLRILGLQTQVQSLRRTASSTGDGDG 398
Q+KR E E+ RI + ++Q A+ + + G
Sbjct: 995 QLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMG 1032
Score = 42.3 bits (95), Expect = 0.003
Identities = 90/378 (23%), Positives = 154/378 (40%), Gaps = 46/378 (12%)
Query: 26 KLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQ 85
K+++LE + + N L SKE+ +E + L E E+ L L +
Sbjct: 93 KIKKLEDEILVMDDQNNKL--SKERKLLEE-RISDLTTNLAEEEEKAKNLTKLKNKHESM 149
Query: 86 LQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQI-NLEIQRVKLKFQ-----EKLQE- 138
+ + V+ + ++ +E + + EQI +L+ Q +LK Q E+LQ
Sbjct: 150 ISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAA 209
Query: 139 LAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMT 198
LA + D + LK ++ + E L E AR K R L L T
Sbjct: 210 LARLDDEIAQKNNALKKIRELEGHISDLQEDLDSE-RAARNKAEKQKRDLGE-ELEALKT 267
Query: 199 LTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAEN 258
++ L + + R ++Q V VL K ++ E E Q+ + Q+ +Q E
Sbjct: 268 ELEDTLDSTATQQELRAKREQEVTVLK----KALDE--ETRSHEAQVQEMRQKHAQAVEE 321
Query: 259 NISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQ 318
+ +R KA+ L K+ EK E A L GEL R L +A ++
Sbjct: 322 LTEQLEQFKRAKAN--------LDKNKQTLEK--ENADLAGEL--------RVLGQAKQE 363
Query: 319 TETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHW---QMKRLTENFEQAQLR 375
E +K L+ V EL+ ++ S E+ R EL +++H +++ +T +A+ +
Sbjct: 364 VEHKKKKLEAQVQELQ-------SKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGK 416
Query: 376 ILGLQTQVQSLRRTASST 393
+ L V SL T
Sbjct: 417 AIKLAKDVASLSSQLQDT 434
Score = 32.7 bits (71), Expect = 2.4
Identities = 35/160 (21%), Positives = 67/160 (41%), Gaps = 4/160 (2%)
Query: 250 QRISQLAENNISLKS---EIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRD 306
+ I QL + +K E+E +AS +A NEK+ + + QL +L
Sbjct: 756 EAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAER 815
Query: 307 EASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLT 366
+A E E + L A L+ + A+++ E+E EE + + R+
Sbjct: 816 ARKQADLEKEELAEELASSLSGRNA-LQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVR 874
Query: 367 ENFEQAQLRILGLQTQVQSLRRTASSTGDGDGENQECTCK 406
+ +QA+ L T+ + ++ S+ + +N+E K
Sbjct: 875 KATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSK 914
Score = 30.7 bits (66), Expect = 9.8
Identities = 24/122 (19%), Positives = 57/122 (46%), Gaps = 6/122 (4%)
Query: 242 EKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGEL 301
EK+ L+ +++ E + K E+ER + E ++++ + + +HE + L
Sbjct: 594 EKETKALS--LARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRAL 651
Query: 302 DRTRDEASRALQRAHEQ---TETVRKCLQTTVAELERQLAAS-RAQVSTAEKEREELKNR 357
+ +E L+ ++ +E + L+ + L+ Q +A+ E++R +L+ +
Sbjct: 652 ETQMEEMKTQLEELEDELQASEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQ 711
Query: 358 LH 359
LH
Sbjct: 712 LH 713
>BC114545-1|AAI14546.1| 1939|Homo sapiens myosin, heavy chain 1,
skeletal muscle, adult protein.
Length = 1939
Score = 55.2 bits (127), Expect = 4e-07
Identities = 80/339 (23%), Positives = 147/339 (43%), Gaps = 37/339 (10%)
Query: 38 ATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQND---QLQDYRVKYL 94
+ T M + ++ FE+ A + R+ EE ++ TLM+E+ND Q+Q
Sbjct: 846 SAETEKEMANMKEEFEKTKEELAKTEAKRKELEE--KMVTLMQEKNDLQLQVQAEADSLA 903
Query: 95 QAQ----QLVEEQRRQXXXXXXXNTRIS--EQINLEIQRVKLKFQEKLQELAPIPDLLKA 148
A+ QL++ + + R E+IN E+ K K +++ EL D L+
Sbjct: 904 DAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLEL 963
Query: 149 TQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQS 208
T +++ + A E+ + L E+ E + + + +L TL +DL
Sbjct: 964 TLAKVEKEKHA---TENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTL--DDL---- 1014
Query: 209 QSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIER 268
Q+E + N + L + E E+ EK++ + +R + E ++ L E
Sbjct: 1015 QAEEDKVNTLTKAKIKLEQQVDDLEGSLEQ---EKKIRMDLERAKRKLEGDLKLAQE--- 1068
Query: 269 LKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQT 328
S + E +++L++K E + L +++ DE + +Q + E LQ
Sbjct: 1069 ---STMDIENDKQQLDEKLKKKEFEMSGLQSKIE---DEQALGMQLQKKIKE-----LQA 1117
Query: 329 TVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTE 367
+ ELE ++ A RA + AEK+R +L L +RL E
Sbjct: 1118 RIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEE 1156
Score = 42.3 bits (95), Expect = 0.003
Identities = 79/396 (19%), Positives = 163/396 (41%), Gaps = 42/396 (10%)
Query: 22 ETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKE 81
ET +L + + L+T + + E++ +Q + LK+ + ++EI +L + E
Sbjct: 1466 ETHAELEASQKESRSLSTELFKIKNAYEESLDQ---LETLKRENKNLQQEISDLTEQIAE 1522
Query: 82 QNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQ-----INLEIQRVKLKFQEKL 136
++ + + Q +Q E+ Q + E+ I LE+ +VK + K+
Sbjct: 1523 GGKRIHELKKIKKQVEQ--EKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKI 1580
Query: 137 QELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTT 196
E D +K +R+ ++ Q+ AE + A L E ++ L
Sbjct: 1581 AEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEI--QLNHANR 1638
Query: 197 MTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLA 256
M + +Q+ + KD +H L ++L+ E E Q+A++ +R + L
Sbjct: 1639 MAAEALRNYRNTQAIL----KDTQLH--LDDALRSQEDLKE------QLAMVERRANLL- 1685
Query: 257 ENNISLKSEIERLKASVIRTEESALANEKRL---QEKMHECAQLGGELDRTRDEASRALQ 313
++EIE L+A++ +TE S E+ L E++ L T+ + +
Sbjct: 1686 ------QAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDIS 1739
Query: 314 RAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKER------EELKNRLHWQMKRLTE 367
+ + E + + + + ++ + + +KE+ E +K L +K L
Sbjct: 1740 QIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQH 1799
Query: 368 NFEQA-QLRILGLQTQVQSLR-RTASSTGDGDGENQ 401
++A QL + G + Q+Q L R G+ + E +
Sbjct: 1800 RLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQK 1835
Score = 41.9 bits (94), Expect = 0.004
Identities = 61/372 (16%), Positives = 145/372 (38%), Gaps = 20/372 (5%)
Query: 21 RETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMK 80
++ KL++ E + GL + + + + + ++ L+ E EEI+ R
Sbjct: 1078 QQLDEKLKKKEFEMSGLQSK---IEDEQALGMQLQKKIKELQARIEELEEEIEAERASRA 1134
Query: 81 EQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELA 140
+ Q D + + + +EE ++++ E Q+++ +E A
Sbjct: 1135 KAEKQRSDLSRELEEISERLEE----AGGATSAQIEMNKKREAEFQKMRRDLEE-----A 1185
Query: 141 PIPDLLKATQMRLKDAQQAQAIAEH--NAEQLARELNCAREKV-VHIFRYLYSLYLVTTM 197
+ A +R K A + E N +++ ++L + ++ + I ++ V+
Sbjct: 1186 TLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKA 1245
Query: 198 TLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEK--PPERGGDEKQMALLNQRISQL 255
E + + ++ + L N L E G +Q+ + +SQL
Sbjct: 1246 KGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQLDEKDTLVSQL 1305
Query: 256 AENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRD---EASRAL 312
+ + +IE LK + ++ A LQ H+C L + + ++ E RA+
Sbjct: 1306 SRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAM 1365
Query: 313 QRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQA 372
+A+ + R +T + +L ++ +++ ++ EE ++ + L + ++
Sbjct: 1366 SKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRL 1425
Query: 373 QLRILGLQTQVQ 384
Q + L V+
Sbjct: 1426 QNEVEDLMIDVE 1437
Score = 39.9 bits (89), Expect = 0.016
Identities = 70/384 (18%), Positives = 164/384 (42%), Gaps = 45/384 (11%)
Query: 24 QNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQN 83
Q ++LE + + + L + E + + N+ K C R +++ E++T +EQ
Sbjct: 1215 QRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLE--KMC-RALEDQLSEIKTKEEEQQ 1271
Query: 84 DQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRIS---EQINLEIQRVKLKFQEKLQELA 140
+ D + + Q E RQ +++S + +I+ +K + +E+++ +
Sbjct: 1272 RLINDLTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKS 1331
Query: 141 PIPDLLKATQMRLKDAQQAQAIAEHNAE-QLARELNCAREKVVHIFRYLYSLYLVTTMTL 199
+ L++++ D + Q E A+ +L R ++ A +V +R Y T +
Sbjct: 1332 ALAHALQSSRHDC-DLLREQYEEEQEAKAELQRAMSKANSEVAQ-WRTKYE-----TDAI 1384
Query: 200 TQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENN 259
+ + +++ ++ + +D HV N+ + A L + +L
Sbjct: 1385 QRTEELEEAKKKLAQRLQDAEEHVEAVNA---------------KCASLEKTKQRLQNEV 1429
Query: 260 ISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEA----------S 309
L ++ER A+ ++ +K L E +C + EL+ ++ E+
Sbjct: 1430 EDLMIDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLSTELFKIK 1489
Query: 310 RALQRAHEQTETVR---KCLQTTVAELERQLAASRAQV---STAEKEREELKNRLHWQMK 363
A + + +Q ET++ K LQ +++L Q+A ++ +K+ E+ K+ L ++
Sbjct: 1490 NAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELKKIKKQVEQEKSELQAALE 1549
Query: 364 RLTENFEQAQLRILGLQTQVQSLR 387
+ E + +IL +Q ++ ++
Sbjct: 1550 EAEASLEHEEGKILRIQLELNQVK 1573
>AY480051-1|AAR95684.1| 4547|Homo sapiens plectin 11 protein.
Length = 4547
Score = 55.2 bits (127), Expect = 4e-07
Identities = 72/378 (19%), Positives = 160/378 (42%), Gaps = 14/378 (3%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTL 78
+ +E Q L++ + + L + E+A E V R EE + L+
Sbjct: 2061 KEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQS 2120
Query: 79 MKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQE 138
+EQ + + ++ E++ + R + + E+++ K ++ L++
Sbjct: 2121 AEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQ 2180
Query: 139 LAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYL-VTTM 197
A + L +++L++ + + + ++L E A + + L+S+ + + +
Sbjct: 2181 KAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEEL 2240
Query: 198 TLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAE 257
+ + + ++++ I R +KD T L + K ++ E A R+ QLAE
Sbjct: 2241 SKLKARIEAENRALILR-DKDNTQRFLQEEAEK-MKQVAEEAARLSVAAQEAARLRQLAE 2298
Query: 258 NNISLKSEI--ERLKASVIRTEESA-LANEKRLQEKMHECAQLGGELDRTRDEASRALQR 314
+++ + + + LK + +E+ L E L ++ E AQ + R +++ + Q+
Sbjct: 2299 EDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQ--EQARRLQEDKEQMAQQ 2356
Query: 315 AHEQTETVRKCLQT-TVAELERQLAASR-----AQVSTAEKEREELKNRLHWQMKRLTEN 368
E+T+ ++ L+ +LE A R A++S A+ EE R Q + + E
Sbjct: 2357 LAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEK 2416
Query: 369 FEQAQLRILGLQTQVQSL 386
+ +L T VQ+L
Sbjct: 2417 LHRTELATQEKVTLVQTL 2434
Score = 48.0 bits (109), Expect = 6e-05
Identities = 63/332 (18%), Positives = 137/332 (41%), Gaps = 16/332 (4%)
Query: 49 EQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXX 108
EQ Q+ V R EE D + L+ E+ +L+ + + + VEE+
Sbjct: 2175 EQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVR 2234
Query: 109 XXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAE 168
+++ +I E + + L+ ++ Q L+ ++K + A A+
Sbjct: 2235 VQMEELSKLKARIEAENRALILRDKDNTQRF------LQEEAEKMKQVAEEAARLSVAAQ 2288
Query: 169 QLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNS 228
+ AR A E + R L L M QE ++++E+ + K+
Sbjct: 2289 EAARLRQLAEEDLAQQ-RALAEKMLKEKMQAVQEATRLKAEAELLQQQKE-LAQEQARRL 2346
Query: 229 LKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQ 288
+ E+ ++ +E Q + + + + + +E ERLK V + E+ Q
Sbjct: 2347 QEDKEQMAQQLAEETQG--FQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQ 2404
Query: 289 EKMHECAQLGGELDRT----RDEAS--RALQRAHEQTETVRKCLQTTVAELERQLAASRA 342
+ ++G +L RT +++ + + L+ +Q++ + L+ +AELER+ +
Sbjct: 2405 RFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQ 2464
Query: 343 QVSTAEKEREELKNRLHWQMKRLTENFEQAQL 374
+ + + EE++ Q+ + T+ +Q+ L
Sbjct: 2465 EAKLLQLKSEEMQTVQQEQLLQETQALQQSFL 2496
Score = 46.8 bits (106), Expect = 1e-04
Identities = 76/366 (20%), Positives = 145/366 (39%), Gaps = 13/366 (3%)
Query: 29 ELEMKFEGLATHTNMLMGSKEQAFEQ-EVNVRALKQCYREAREEIDELRTLMKEQNDQLQ 87
+L + L T T+ + + + E R +Q E RE + E+ +++Q QL
Sbjct: 1318 DLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQR-QLA 1376
Query: 88 DYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDL-L 146
+ + QA+ E + ++ E+ ++ Q+ K QE+LQ+L + +
Sbjct: 1377 E---AHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEI 1433
Query: 147 KATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFG 206
+A + + A++++ E + +L + L +L Q+
Sbjct: 1434 QAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQ 1493
Query: 207 QSQSEIGRGNKDQTVHVLLHN-SLKPPEKPPERGGDEKQMAL--LNQRISQLAENNISLK 263
+ + R +D++ L K EKQ AL L + Q E L+
Sbjct: 1494 EEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLR 1553
Query: 264 -SEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETV 322
+E+ER + + E + + E LQ K A+ +L+R+ E A+ + E+ E
Sbjct: 1554 QAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAE-- 1611
Query: 323 RKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQLRILGLQTQ 382
R+ Q AE R+ A R K E L+ RL + ++ QA+ + +
Sbjct: 1612 RRAQQQAEAERARE-EAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAE 1670
Query: 383 VQSLRR 388
++ RR
Sbjct: 1671 REARRR 1676
Score = 46.4 bits (105), Expect = 2e-04
Identities = 80/375 (21%), Positives = 147/375 (39%), Gaps = 32/375 (8%)
Query: 17 RCQHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELR 76
R + R Q R+L++ E A + K AF + + L+Q ++ + +D+LR
Sbjct: 2023 RLRERAEQESARQLQLAQE--AAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLR 2080
Query: 77 TLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKL 136
+ ++ +QA++ + RRQ E +R+K +E+
Sbjct: 2081 GEAEAARRAAEEAEEARVQAEREAAQSRRQVE---------------EAERLKQSAEEQA 2125
Query: 137 QELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTT 196
Q A +A +L+ + +A AEQ A A + + + L
Sbjct: 2126 QARAQ----AQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQK 2181
Query: 197 MTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLA 256
+ QE + Q E K+ L + E +R E+++ + ++ +L+
Sbjct: 2182 AQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELS 2241
Query: 257 ENNISLKSEIE-RLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRA 315
+ LK+ IE +A ++R +++ + EKM + A+ L EA+R Q A
Sbjct: 2242 K----LKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLA 2297
Query: 316 HEQTETVRKCLQTTVAELERQLAASRAQVSTAEKE-REELKNRLHWQMKRLTENFEQAQL 374
E R + + E+ A A AE E ++ K Q +RL E+ EQ
Sbjct: 2298 EEDLAQQRALAEKMLK--EKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQ 2355
Query: 375 RILGLQTQVQSLRRT 389
+ L + Q +RT
Sbjct: 2356 Q---LAEETQGFQRT 2367
Score = 46.4 bits (105), Expect = 2e-04
Identities = 74/345 (21%), Positives = 147/345 (42%), Gaps = 20/345 (5%)
Query: 21 RETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRAL-KQCYREAREEIDELRTLM 79
+E K++++ + L+ ++ A E RAL ++ +E + + E L
Sbjct: 2267 QEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLK 2326
Query: 80 KEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQEL 139
E Q + QA++L E++ + + E QR +L+ + + L
Sbjct: 2327 AEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQR-QLEMSAEAERL 2385
Query: 140 A-PIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMT 198
+ ++ +A +DAQ+ + AE E+L R +EKV + +L + +
Sbjct: 2386 KLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLV----QTLEIQRQQS 2441
Query: 199 LTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQ--LA 256
+ ++ +E+ R K++ LK E + ++Q+ Q + Q L+
Sbjct: 2442 DHDAERLREAIAELER-EKEKLQQEAKLLQLKSEEMQTVQ---QEQLLQETQALQQSFLS 2497
Query: 257 ENNISLKSE--IERLKASVIRTEESALANEKRL-QEKMHECAQLGGELDRTRDEASRALQ 313
E + L+ E IE+ KA + + + +A ++L +E+ + Q+ E R A +
Sbjct: 2498 EKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARR 2557
Query: 314 RAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRL 358
R HE E VR+ Q + +LE+Q R Q +E + L+ +L
Sbjct: 2558 RQHEAEEGVRR-KQEELQQLEQQ---RRQQEELLAEENQRLREQL 2598
Score = 38.3 bits (85), Expect = 0.049
Identities = 89/407 (21%), Positives = 148/407 (36%), Gaps = 45/407 (11%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKEQA---FEQEVNVRALKQCYRE-----ARE 70
Q R Q +L++L E + E++ E+E+ V L+ E A
Sbjct: 1414 QKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEG 1473
Query: 71 EIDELRTLMKE---QNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQR 127
E+ LR +E Q Q Q+ + + Q +++RQ + + E QR
Sbjct: 1474 ELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQR 1533
Query: 128 VKLKFQE-KLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAE-QLARELNCAREKVVHIF 185
+E +LQ L +A R + Q A A+ +AE +L + EK +
Sbjct: 1534 ALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLE 1593
Query: 186 RYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKD--------------------QTVHVLL 225
R L ++ + + Q Q+E R ++ Q V
Sbjct: 1594 RSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQ 1653
Query: 226 HNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEK 285
SL E ++ E++ + Q + E+E+ + T + LA E+
Sbjct: 1654 QKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQ 1713
Query: 286 RLQEKMHECAQ-------LGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLA 338
L E Q L EL R + EA+ A Q+ E + K AE+E LA
Sbjct: 1714 ELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVR----AEMEVLLA 1769
Query: 339 ASRAQVSTAEKEREELKNRLHWQMKRLTENFEQ-AQLRILGLQTQVQ 384
+ + E+ K RL + R E E+ A+LR L + + Q
Sbjct: 1770 SKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQ 1816
Score = 38.3 bits (85), Expect = 0.049
Identities = 31/134 (23%), Positives = 57/134 (42%), Gaps = 3/134 (2%)
Query: 47 SKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQ 106
+K Q +E R +Q +E + + + + Q++ + R K + QQL +++R+Q
Sbjct: 2525 AKAQQLREEQQ-RQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQ 2583
Query: 107 XXXXXXXNTRISEQINL--EIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAE 164
N R+ EQ+ L E R L E++ D A+A E
Sbjct: 2584 EELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPE 2643
Query: 165 HNAEQLARELNCAR 178
H+ + L R+++ R
Sbjct: 2644 HSFDGLRRKVSAQR 2657
Score = 37.1 bits (82), Expect = 0.11
Identities = 75/390 (19%), Positives = 158/390 (40%), Gaps = 30/390 (7%)
Query: 17 RCQHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELR 76
R + + + +R+ E+ + L + G+ +Q E + L R E+ ++ R
Sbjct: 1674 RRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRL----RAETEQGEQQR 1729
Query: 77 TLMKEQNDQLQDYRVKYLQAQQLVEEQ----RRQXXXXXXXNTRISEQINLEIQRVKLKF 132
L++E+ +LQ Q +Q +E + R + R E+ ++ K +
Sbjct: 1730 QLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRL 1789
Query: 133 QEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLY 192
+ + + + + ++A++ + +AE +A + E E+V + L ++
Sbjct: 1790 EAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEA----ERV--LAEKLAAIG 1843
Query: 193 LVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGD-EKQMALLN-- 249
T + E + ++E R + L+ E+ + D E+++A L
Sbjct: 1844 EATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLE--EQAAQHKADIEERLAQLRKA 1901
Query: 250 -----QRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRT 304
+R L E+ + + ++E ++ + E A A + L+ ++ + R+
Sbjct: 1902 SDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRS 1961
Query: 305 RD----EASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHW 360
++ EA+R Q A E+ R+ + L + A+R Q A +E E LK ++
Sbjct: 1962 KEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAAR-QRKAALEEVERLKAKVE- 2019
Query: 361 QMKRLTENFEQAQLRILGLQTQVQSLRRTA 390
+ +RL E EQ R L L + R A
Sbjct: 2020 EARRLRERAEQESARQLQLAQEAAQKRLQA 2049
Score = 36.7 bits (81), Expect = 0.15
Identities = 73/350 (20%), Positives = 133/350 (38%), Gaps = 18/350 (5%)
Query: 29 ELEMKFEGLATHTNMLMGSKEQAFEQEVNVRAL----KQCYREAREEIDELRTLMKEQND 84
ELE++ + ++ + SKEQA + R L ++ REA E + + +E
Sbjct: 1943 ELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAAR 2002
Query: 85 QLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPD 144
Q + + + + VEE RR + R Q+ E + +L+ +EK A +
Sbjct: 2003 QRKAALEEVERLKAKVEEARRLRERAEQESAR-QLQLAQEAAQKRLQAEEKAHAFA-VQQ 2060
Query: 145 LLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDL 204
+ Q L+ Q AE R A E V R + + + +
Sbjct: 2061 KEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQ----SRRQVEEAER 2116
Query: 205 FGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQL-AENNISLK 263
QS E + K E+ R +Q AL ++ + E +
Sbjct: 2117 LKQSAEEQAQARAQ--AQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFA 2174
Query: 264 SEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVR 323
+ R KA V E+ +L+E H+ L EL R + EA+ A R Q E
Sbjct: 2175 EQTLRQKAQV---EQELTTLRLQLEETDHQKNLLDEELQRLKAEATEA-ARQRSQVEEEL 2230
Query: 324 KCLQTTVAELERQLAASRAQ-VSTAEKEREELKNRLHWQMKRLTENFEQA 372
++ + EL + A A+ + ++++ + L + +++ + E+A
Sbjct: 2231 FSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEA 2280
Score = 34.7 bits (76), Expect = 0.60
Identities = 38/160 (23%), Positives = 76/160 (47%), Gaps = 13/160 (8%)
Query: 27 LRELEMKFEGLATHTNMLMGSKE--QAFEQEV---NVRALKQCYREAREEIDELRTLMKE 81
+ ELE + E L +L E Q +QE +AL+Q + ++ + + +++
Sbjct: 2452 IAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQ 2511
Query: 82 QNDQLQD-YRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELA 140
+ +L+ ++ + +AQQL EEQ+RQ R+ + E +R + + +E ++
Sbjct: 2512 EKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASME-EARRRQHEAEEGVRRKQ 2570
Query: 141 PIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREK 180
+L + Q R QQ + +AE N ++L +L E+
Sbjct: 2571 --EELQQLEQQR---RQQEELLAEEN-QRLREQLQLLEEQ 2604
>AY480050-1|AAR95683.1| 4551|Homo sapiens plectin 10 protein.
Length = 4551
Score = 55.2 bits (127), Expect = 4e-07
Identities = 72/378 (19%), Positives = 160/378 (42%), Gaps = 14/378 (3%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTL 78
+ +E Q L++ + + L + E+A E V R EE + L+
Sbjct: 2065 KEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQS 2124
Query: 79 MKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQE 138
+EQ + + ++ E++ + R + + E+++ K ++ L++
Sbjct: 2125 AEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQ 2184
Query: 139 LAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYL-VTTM 197
A + L +++L++ + + + ++L E A + + L+S+ + + +
Sbjct: 2185 KAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEEL 2244
Query: 198 TLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAE 257
+ + + ++++ I R +KD T L + K ++ E A R+ QLAE
Sbjct: 2245 SKLKARIEAENRALILR-DKDNTQRFLQEEAEK-MKQVAEEAARLSVAAQEAARLRQLAE 2302
Query: 258 NNISLKSEI--ERLKASVIRTEESA-LANEKRLQEKMHECAQLGGELDRTRDEASRALQR 314
+++ + + + LK + +E+ L E L ++ E AQ + R +++ + Q+
Sbjct: 2303 EDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQ--EQARRLQEDKEQMAQQ 2360
Query: 315 AHEQTETVRKCLQT-TVAELERQLAASR-----AQVSTAEKEREELKNRLHWQMKRLTEN 368
E+T+ ++ L+ +LE A R A++S A+ EE R Q + + E
Sbjct: 2361 LAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEK 2420
Query: 369 FEQAQLRILGLQTQVQSL 386
+ +L T VQ+L
Sbjct: 2421 LHRTELATQEKVTLVQTL 2438
Score = 48.0 bits (109), Expect = 6e-05
Identities = 63/332 (18%), Positives = 137/332 (41%), Gaps = 16/332 (4%)
Query: 49 EQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXX 108
EQ Q+ V R EE D + L+ E+ +L+ + + + VEE+
Sbjct: 2179 EQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVR 2238
Query: 109 XXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAE 168
+++ +I E + + L+ ++ Q L+ ++K + A A+
Sbjct: 2239 VQMEELSKLKARIEAENRALILRDKDNTQRF------LQEEAEKMKQVAEEAARLSVAAQ 2292
Query: 169 QLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNS 228
+ AR A E + R L L M QE ++++E+ + K+
Sbjct: 2293 EAARLRQLAEEDLAQQ-RALAEKMLKEKMQAVQEATRLKAEAELLQQQKE-LAQEQARRL 2350
Query: 229 LKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQ 288
+ E+ ++ +E Q + + + + + +E ERLK V + E+ Q
Sbjct: 2351 QEDKEQMAQQLAEETQG--FQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQ 2408
Query: 289 EKMHECAQLGGELDRT----RDEAS--RALQRAHEQTETVRKCLQTTVAELERQLAASRA 342
+ ++G +L RT +++ + + L+ +Q++ + L+ +AELER+ +
Sbjct: 2409 RFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQ 2468
Query: 343 QVSTAEKEREELKNRLHWQMKRLTENFEQAQL 374
+ + + EE++ Q+ + T+ +Q+ L
Sbjct: 2469 EAKLLQLKSEEMQTVQQEQLLQETQALQQSFL 2500
Score = 46.8 bits (106), Expect = 1e-04
Identities = 76/366 (20%), Positives = 145/366 (39%), Gaps = 13/366 (3%)
Query: 29 ELEMKFEGLATHTNMLMGSKEQAFEQ-EVNVRALKQCYREAREEIDELRTLMKEQNDQLQ 87
+L + L T T+ + + + E R +Q E RE + E+ +++Q QL
Sbjct: 1322 DLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQR-QLA 1380
Query: 88 DYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDL-L 146
+ + QA+ E + ++ E+ ++ Q+ K QE+LQ+L + +
Sbjct: 1381 E---AHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEI 1437
Query: 147 KATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFG 206
+A + + A++++ E + +L + L +L Q+
Sbjct: 1438 QAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQ 1497
Query: 207 QSQSEIGRGNKDQTVHVLLHN-SLKPPEKPPERGGDEKQMAL--LNQRISQLAENNISLK 263
+ + R +D++ L K EKQ AL L + Q E L+
Sbjct: 1498 EEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLR 1557
Query: 264 -SEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETV 322
+E+ER + + E + + E LQ K A+ +L+R+ E A+ + E+ E
Sbjct: 1558 QAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAE-- 1615
Query: 323 RKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQLRILGLQTQ 382
R+ Q AE R+ A R K E L+ RL + ++ QA+ + +
Sbjct: 1616 RRAQQQAEAERARE-EAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAE 1674
Query: 383 VQSLRR 388
++ RR
Sbjct: 1675 REARRR 1680
Score = 46.4 bits (105), Expect = 2e-04
Identities = 80/375 (21%), Positives = 147/375 (39%), Gaps = 32/375 (8%)
Query: 17 RCQHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELR 76
R + R Q R+L++ E A + K AF + + L+Q ++ + +D+LR
Sbjct: 2027 RLRERAEQESARQLQLAQE--AAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLR 2084
Query: 77 TLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKL 136
+ ++ +QA++ + RRQ E +R+K +E+
Sbjct: 2085 GEAEAARRAAEEAEEARVQAEREAAQSRRQVE---------------EAERLKQSAEEQA 2129
Query: 137 QELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTT 196
Q A +A +L+ + +A AEQ A A + + + L
Sbjct: 2130 QARAQ----AQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQK 2185
Query: 197 MTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLA 256
+ QE + Q E K+ L + E +R E+++ + ++ +L+
Sbjct: 2186 AQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELS 2245
Query: 257 ENNISLKSEIE-RLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRA 315
+ LK+ IE +A ++R +++ + EKM + A+ L EA+R Q A
Sbjct: 2246 K----LKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLA 2301
Query: 316 HEQTETVRKCLQTTVAELERQLAASRAQVSTAEKE-REELKNRLHWQMKRLTENFEQAQL 374
E R + + E+ A A AE E ++ K Q +RL E+ EQ
Sbjct: 2302 EEDLAQQRALAEKMLK--EKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQ 2359
Query: 375 RILGLQTQVQSLRRT 389
+ L + Q +RT
Sbjct: 2360 Q---LAEETQGFQRT 2371
Score = 46.4 bits (105), Expect = 2e-04
Identities = 74/345 (21%), Positives = 147/345 (42%), Gaps = 20/345 (5%)
Query: 21 RETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRAL-KQCYREAREEIDELRTLM 79
+E K++++ + L+ ++ A E RAL ++ +E + + E L
Sbjct: 2271 QEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLK 2330
Query: 80 KEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQEL 139
E Q + QA++L E++ + + E QR +L+ + + L
Sbjct: 2331 AEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQR-QLEMSAEAERL 2389
Query: 140 A-PIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMT 198
+ ++ +A +DAQ+ + AE E+L R +EKV + +L + +
Sbjct: 2390 KLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLV----QTLEIQRQQS 2445
Query: 199 LTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQ--LA 256
+ ++ +E+ R K++ LK E + ++Q+ Q + Q L+
Sbjct: 2446 DHDAERLREAIAELER-EKEKLQQEAKLLQLKSEEMQTVQ---QEQLLQETQALQQSFLS 2501
Query: 257 ENNISLKSE--IERLKASVIRTEESALANEKRL-QEKMHECAQLGGELDRTRDEASRALQ 313
E + L+ E IE+ KA + + + +A ++L +E+ + Q+ E R A +
Sbjct: 2502 EKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARR 2561
Query: 314 RAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRL 358
R HE E VR+ Q + +LE+Q R Q +E + L+ +L
Sbjct: 2562 RQHEAEEGVRR-KQEELQQLEQQ---RRQQEELLAEENQRLREQL 2602
Score = 38.3 bits (85), Expect = 0.049
Identities = 89/407 (21%), Positives = 148/407 (36%), Gaps = 45/407 (11%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKEQA---FEQEVNVRALKQCYRE-----ARE 70
Q R Q +L++L E + E++ E+E+ V L+ E A
Sbjct: 1418 QKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEG 1477
Query: 71 EIDELRTLMKE---QNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQR 127
E+ LR +E Q Q Q+ + + Q +++RQ + + E QR
Sbjct: 1478 ELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQR 1537
Query: 128 VKLKFQE-KLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAE-QLARELNCAREKVVHIF 185
+E +LQ L +A R + Q A A+ +AE +L + EK +
Sbjct: 1538 ALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLE 1597
Query: 186 RYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKD--------------------QTVHVLL 225
R L ++ + + Q Q+E R ++ Q V
Sbjct: 1598 RSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQ 1657
Query: 226 HNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEK 285
SL E ++ E++ + Q + E+E+ + T + LA E+
Sbjct: 1658 QKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQ 1717
Query: 286 RLQEKMHECAQ-------LGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLA 338
L E Q L EL R + EA+ A Q+ E + K AE+E LA
Sbjct: 1718 ELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVR----AEMEVLLA 1773
Query: 339 ASRAQVSTAEKEREELKNRLHWQMKRLTENFEQ-AQLRILGLQTQVQ 384
+ + E+ K RL + R E E+ A+LR L + + Q
Sbjct: 1774 SKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQ 1820
Score = 38.3 bits (85), Expect = 0.049
Identities = 31/134 (23%), Positives = 57/134 (42%), Gaps = 3/134 (2%)
Query: 47 SKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQ 106
+K Q +E R +Q +E + + + + Q++ + R K + QQL +++R+Q
Sbjct: 2529 AKAQQLREEQQ-RQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQ 2587
Query: 107 XXXXXXXNTRISEQINL--EIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAE 164
N R+ EQ+ L E R L E++ D A+A E
Sbjct: 2588 EELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPE 2647
Query: 165 HNAEQLARELNCAR 178
H+ + L R+++ R
Sbjct: 2648 HSFDGLRRKVSAQR 2661
Score = 37.1 bits (82), Expect = 0.11
Identities = 75/390 (19%), Positives = 158/390 (40%), Gaps = 30/390 (7%)
Query: 17 RCQHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELR 76
R + + + +R+ E+ + L + G+ +Q E + L R E+ ++ R
Sbjct: 1678 RRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRL----RAETEQGEQQR 1733
Query: 77 TLMKEQNDQLQDYRVKYLQAQQLVEEQ----RRQXXXXXXXNTRISEQINLEIQRVKLKF 132
L++E+ +LQ Q +Q +E + R + R E+ ++ K +
Sbjct: 1734 QLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRL 1793
Query: 133 QEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLY 192
+ + + + + ++A++ + +AE +A + E E+V + L ++
Sbjct: 1794 EAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEA----ERV--LAEKLAAIG 1847
Query: 193 LVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGD-EKQMALLN-- 249
T + E + ++E R + L+ E+ + D E+++A L
Sbjct: 1848 EATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLE--EQAAQHKADIEERLAQLRKA 1905
Query: 250 -----QRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRT 304
+R L E+ + + ++E ++ + E A A + L+ ++ + R+
Sbjct: 1906 SDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRS 1965
Query: 305 RD----EASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHW 360
++ EA+R Q A E+ R+ + L + A+R Q A +E E LK ++
Sbjct: 1966 KEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAAR-QRKAALEEVERLKAKVE- 2023
Query: 361 QMKRLTENFEQAQLRILGLQTQVQSLRRTA 390
+ +RL E EQ R L L + R A
Sbjct: 2024 EARRLRERAEQESARQLQLAQEAAQKRLQA 2053
Score = 36.7 bits (81), Expect = 0.15
Identities = 73/350 (20%), Positives = 133/350 (38%), Gaps = 18/350 (5%)
Query: 29 ELEMKFEGLATHTNMLMGSKEQAFEQEVNVRAL----KQCYREAREEIDELRTLMKEQND 84
ELE++ + ++ + SKEQA + R L ++ REA E + + +E
Sbjct: 1947 ELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAAR 2006
Query: 85 QLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPD 144
Q + + + + VEE RR + R Q+ E + +L+ +EK A +
Sbjct: 2007 QRKAALEEVERLKAKVEEARRLRERAEQESAR-QLQLAQEAAQKRLQAEEKAHAFA-VQQ 2064
Query: 145 LLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDL 204
+ Q L+ Q AE R A E V R + + + +
Sbjct: 2065 KEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQ----SRRQVEEAER 2120
Query: 205 FGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQL-AENNISLK 263
QS E + K E+ R +Q AL ++ + E +
Sbjct: 2121 LKQSAEEQAQARAQ--AQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFA 2178
Query: 264 SEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVR 323
+ R KA V E+ +L+E H+ L EL R + EA+ A R Q E
Sbjct: 2179 EQTLRQKAQV---EQELTTLRLQLEETDHQKNLLDEELQRLKAEATEA-ARQRSQVEEEL 2234
Query: 324 KCLQTTVAELERQLAASRAQ-VSTAEKEREELKNRLHWQMKRLTENFEQA 372
++ + EL + A A+ + ++++ + L + +++ + E+A
Sbjct: 2235 FSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEA 2284
Score = 34.7 bits (76), Expect = 0.60
Identities = 38/160 (23%), Positives = 76/160 (47%), Gaps = 13/160 (8%)
Query: 27 LRELEMKFEGLATHTNMLMGSKE--QAFEQEV---NVRALKQCYREAREEIDELRTLMKE 81
+ ELE + E L +L E Q +QE +AL+Q + ++ + + +++
Sbjct: 2456 IAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQ 2515
Query: 82 QNDQLQD-YRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELA 140
+ +L+ ++ + +AQQL EEQ+RQ R+ + E +R + + +E ++
Sbjct: 2516 EKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASME-EARRRQHEAEEGVRRKQ 2574
Query: 141 PIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREK 180
+L + Q R QQ + +AE N ++L +L E+
Sbjct: 2575 --EELQQLEQQR---RQQEELLAEEN-QRLREQLQLLEEQ 2608
>AY480049-1|AAR95682.1| 4547|Homo sapiens plectin 8 protein.
Length = 4547
Score = 55.2 bits (127), Expect = 4e-07
Identities = 72/378 (19%), Positives = 160/378 (42%), Gaps = 14/378 (3%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTL 78
+ +E Q L++ + + L + E+A E V R EE + L+
Sbjct: 2061 KEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQS 2120
Query: 79 MKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQE 138
+EQ + + ++ E++ + R + + E+++ K ++ L++
Sbjct: 2121 AEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQ 2180
Query: 139 LAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYL-VTTM 197
A + L +++L++ + + + ++L E A + + L+S+ + + +
Sbjct: 2181 KAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEEL 2240
Query: 198 TLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAE 257
+ + + ++++ I R +KD T L + K ++ E A R+ QLAE
Sbjct: 2241 SKLKARIEAENRALILR-DKDNTQRFLQEEAEK-MKQVAEEAARLSVAAQEAARLRQLAE 2298
Query: 258 NNISLKSEI--ERLKASVIRTEESA-LANEKRLQEKMHECAQLGGELDRTRDEASRALQR 314
+++ + + + LK + +E+ L E L ++ E AQ + R +++ + Q+
Sbjct: 2299 EDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQ--EQARRLQEDKEQMAQQ 2356
Query: 315 AHEQTETVRKCLQT-TVAELERQLAASR-----AQVSTAEKEREELKNRLHWQMKRLTEN 368
E+T+ ++ L+ +LE A R A++S A+ EE R Q + + E
Sbjct: 2357 LAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEK 2416
Query: 369 FEQAQLRILGLQTQVQSL 386
+ +L T VQ+L
Sbjct: 2417 LHRTELATQEKVTLVQTL 2434
Score = 48.0 bits (109), Expect = 6e-05
Identities = 63/332 (18%), Positives = 137/332 (41%), Gaps = 16/332 (4%)
Query: 49 EQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXX 108
EQ Q+ V R EE D + L+ E+ +L+ + + + VEE+
Sbjct: 2175 EQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVR 2234
Query: 109 XXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAE 168
+++ +I E + + L+ ++ Q L+ ++K + A A+
Sbjct: 2235 VQMEELSKLKARIEAENRALILRDKDNTQRF------LQEEAEKMKQVAEEAARLSVAAQ 2288
Query: 169 QLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNS 228
+ AR A E + R L L M QE ++++E+ + K+
Sbjct: 2289 EAARLRQLAEEDLAQQ-RALAEKMLKEKMQAVQEATRLKAEAELLQQQKE-LAQEQARRL 2346
Query: 229 LKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQ 288
+ E+ ++ +E Q + + + + + +E ERLK V + E+ Q
Sbjct: 2347 QEDKEQMAQQLAEETQG--FQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQ 2404
Query: 289 EKMHECAQLGGELDRT----RDEAS--RALQRAHEQTETVRKCLQTTVAELERQLAASRA 342
+ ++G +L RT +++ + + L+ +Q++ + L+ +AELER+ +
Sbjct: 2405 RFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQ 2464
Query: 343 QVSTAEKEREELKNRLHWQMKRLTENFEQAQL 374
+ + + EE++ Q+ + T+ +Q+ L
Sbjct: 2465 EAKLLQLKSEEMQTVQQEQLLQETQALQQSFL 2496
Score = 46.8 bits (106), Expect = 1e-04
Identities = 76/366 (20%), Positives = 145/366 (39%), Gaps = 13/366 (3%)
Query: 29 ELEMKFEGLATHTNMLMGSKEQAFEQ-EVNVRALKQCYREAREEIDELRTLMKEQNDQLQ 87
+L + L T T+ + + + E R +Q E RE + E+ +++Q QL
Sbjct: 1318 DLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQR-QLA 1376
Query: 88 DYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDL-L 146
+ + QA+ E + ++ E+ ++ Q+ K QE+LQ+L + +
Sbjct: 1377 E---AHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEI 1433
Query: 147 KATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFG 206
+A + + A++++ E + +L + L +L Q+
Sbjct: 1434 QAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQ 1493
Query: 207 QSQSEIGRGNKDQTVHVLLHN-SLKPPEKPPERGGDEKQMAL--LNQRISQLAENNISLK 263
+ + R +D++ L K EKQ AL L + Q E L+
Sbjct: 1494 EEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLR 1553
Query: 264 -SEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETV 322
+E+ER + + E + + E LQ K A+ +L+R+ E A+ + E+ E
Sbjct: 1554 QAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAE-- 1611
Query: 323 RKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQLRILGLQTQ 382
R+ Q AE R+ A R K E L+ RL + ++ QA+ + +
Sbjct: 1612 RRAQQQAEAERARE-EAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAE 1670
Query: 383 VQSLRR 388
++ RR
Sbjct: 1671 REARRR 1676
Score = 46.4 bits (105), Expect = 2e-04
Identities = 80/375 (21%), Positives = 147/375 (39%), Gaps = 32/375 (8%)
Query: 17 RCQHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELR 76
R + R Q R+L++ E A + K AF + + L+Q ++ + +D+LR
Sbjct: 2023 RLRERAEQESARQLQLAQE--AAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLR 2080
Query: 77 TLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKL 136
+ ++ +QA++ + RRQ E +R+K +E+
Sbjct: 2081 GEAEAARRAAEEAEEARVQAEREAAQSRRQVE---------------EAERLKQSAEEQA 2125
Query: 137 QELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTT 196
Q A +A +L+ + +A AEQ A A + + + L
Sbjct: 2126 QARAQ----AQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQK 2181
Query: 197 MTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLA 256
+ QE + Q E K+ L + E +R E+++ + ++ +L+
Sbjct: 2182 AQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELS 2241
Query: 257 ENNISLKSEIE-RLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRA 315
+ LK+ IE +A ++R +++ + EKM + A+ L EA+R Q A
Sbjct: 2242 K----LKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLA 2297
Query: 316 HEQTETVRKCLQTTVAELERQLAASRAQVSTAEKE-REELKNRLHWQMKRLTENFEQAQL 374
E R + + E+ A A AE E ++ K Q +RL E+ EQ
Sbjct: 2298 EEDLAQQRALAEKMLK--EKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQ 2355
Query: 375 RILGLQTQVQSLRRT 389
+ L + Q +RT
Sbjct: 2356 Q---LAEETQGFQRT 2367
Score = 46.4 bits (105), Expect = 2e-04
Identities = 74/345 (21%), Positives = 147/345 (42%), Gaps = 20/345 (5%)
Query: 21 RETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRAL-KQCYREAREEIDELRTLM 79
+E K++++ + L+ ++ A E RAL ++ +E + + E L
Sbjct: 2267 QEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLK 2326
Query: 80 KEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQEL 139
E Q + QA++L E++ + + E QR +L+ + + L
Sbjct: 2327 AEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQR-QLEMSAEAERL 2385
Query: 140 A-PIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMT 198
+ ++ +A +DAQ+ + AE E+L R +EKV + +L + +
Sbjct: 2386 KLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLV----QTLEIQRQQS 2441
Query: 199 LTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQ--LA 256
+ ++ +E+ R K++ LK E + ++Q+ Q + Q L+
Sbjct: 2442 DHDAERLREAIAELER-EKEKLQQEAKLLQLKSEEMQTVQ---QEQLLQETQALQQSFLS 2497
Query: 257 ENNISLKSE--IERLKASVIRTEESALANEKRL-QEKMHECAQLGGELDRTRDEASRALQ 313
E + L+ E IE+ KA + + + +A ++L +E+ + Q+ E R A +
Sbjct: 2498 EKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARR 2557
Query: 314 RAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRL 358
R HE E VR+ Q + +LE+Q R Q +E + L+ +L
Sbjct: 2558 RQHEAEEGVRR-KQEELQQLEQQ---RRQQEELLAEENQRLREQL 2598
Score = 38.3 bits (85), Expect = 0.049
Identities = 89/407 (21%), Positives = 148/407 (36%), Gaps = 45/407 (11%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKEQA---FEQEVNVRALKQCYRE-----ARE 70
Q R Q +L++L E + E++ E+E+ V L+ E A
Sbjct: 1414 QKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEG 1473
Query: 71 EIDELRTLMKE---QNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQR 127
E+ LR +E Q Q Q+ + + Q +++RQ + + E QR
Sbjct: 1474 ELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQR 1533
Query: 128 VKLKFQE-KLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAE-QLARELNCAREKVVHIF 185
+E +LQ L +A R + Q A A+ +AE +L + EK +
Sbjct: 1534 ALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLE 1593
Query: 186 RYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKD--------------------QTVHVLL 225
R L ++ + + Q Q+E R ++ Q V
Sbjct: 1594 RSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQ 1653
Query: 226 HNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEK 285
SL E ++ E++ + Q + E+E+ + T + LA E+
Sbjct: 1654 QKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQ 1713
Query: 286 RLQEKMHECAQ-------LGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLA 338
L E Q L EL R + EA+ A Q+ E + K AE+E LA
Sbjct: 1714 ELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVR----AEMEVLLA 1769
Query: 339 ASRAQVSTAEKEREELKNRLHWQMKRLTENFEQ-AQLRILGLQTQVQ 384
+ + E+ K RL + R E E+ A+LR L + + Q
Sbjct: 1770 SKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQ 1816
Score = 38.3 bits (85), Expect = 0.049
Identities = 31/134 (23%), Positives = 57/134 (42%), Gaps = 3/134 (2%)
Query: 47 SKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQ 106
+K Q +E R +Q +E + + + + Q++ + R K + QQL +++R+Q
Sbjct: 2525 AKAQQLREEQQ-RQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQ 2583
Query: 107 XXXXXXXNTRISEQINL--EIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAE 164
N R+ EQ+ L E R L E++ D A+A E
Sbjct: 2584 EELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPE 2643
Query: 165 HNAEQLARELNCAR 178
H+ + L R+++ R
Sbjct: 2644 HSFDGLRRKVSAQR 2657
Score = 37.1 bits (82), Expect = 0.11
Identities = 75/390 (19%), Positives = 158/390 (40%), Gaps = 30/390 (7%)
Query: 17 RCQHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELR 76
R + + + +R+ E+ + L + G+ +Q E + L R E+ ++ R
Sbjct: 1674 RRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRL----RAETEQGEQQR 1729
Query: 77 TLMKEQNDQLQDYRVKYLQAQQLVEEQ----RRQXXXXXXXNTRISEQINLEIQRVKLKF 132
L++E+ +LQ Q +Q +E + R + R E+ ++ K +
Sbjct: 1730 QLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRL 1789
Query: 133 QEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLY 192
+ + + + + ++A++ + +AE +A + E E+V + L ++
Sbjct: 1790 EAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEA----ERV--LAEKLAAIG 1843
Query: 193 LVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGD-EKQMALLN-- 249
T + E + ++E R + L+ E+ + D E+++A L
Sbjct: 1844 EATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLE--EQAAQHKADIEERLAQLRKA 1901
Query: 250 -----QRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRT 304
+R L E+ + + ++E ++ + E A A + L+ ++ + R+
Sbjct: 1902 SDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRS 1961
Query: 305 RD----EASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHW 360
++ EA+R Q A E+ R+ + L + A+R Q A +E E LK ++
Sbjct: 1962 KEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAAR-QRKAALEEVERLKAKVE- 2019
Query: 361 QMKRLTENFEQAQLRILGLQTQVQSLRRTA 390
+ +RL E EQ R L L + R A
Sbjct: 2020 EARRLRERAEQESARQLQLAQEAAQKRLQA 2049
Score = 36.7 bits (81), Expect = 0.15
Identities = 73/350 (20%), Positives = 133/350 (38%), Gaps = 18/350 (5%)
Query: 29 ELEMKFEGLATHTNMLMGSKEQAFEQEVNVRAL----KQCYREAREEIDELRTLMKEQND 84
ELE++ + ++ + SKEQA + R L ++ REA E + + +E
Sbjct: 1943 ELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAAR 2002
Query: 85 QLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPD 144
Q + + + + VEE RR + R Q+ E + +L+ +EK A +
Sbjct: 2003 QRKAALEEVERLKAKVEEARRLRERAEQESAR-QLQLAQEAAQKRLQAEEKAHAFA-VQQ 2060
Query: 145 LLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDL 204
+ Q L+ Q AE R A E V R + + + +
Sbjct: 2061 KEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQ----SRRQVEEAER 2116
Query: 205 FGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQL-AENNISLK 263
QS E + K E+ R +Q AL ++ + E +
Sbjct: 2117 LKQSAEEQAQARAQ--AQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFA 2174
Query: 264 SEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVR 323
+ R KA V E+ +L+E H+ L EL R + EA+ A R Q E
Sbjct: 2175 EQTLRQKAQV---EQELTTLRLQLEETDHQKNLLDEELQRLKAEATEA-ARQRSQVEEEL 2230
Query: 324 KCLQTTVAELERQLAASRAQ-VSTAEKEREELKNRLHWQMKRLTENFEQA 372
++ + EL + A A+ + ++++ + L + +++ + E+A
Sbjct: 2231 FSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEA 2280
Score = 34.7 bits (76), Expect = 0.60
Identities = 38/160 (23%), Positives = 76/160 (47%), Gaps = 13/160 (8%)
Query: 27 LRELEMKFEGLATHTNMLMGSKE--QAFEQEV---NVRALKQCYREAREEIDELRTLMKE 81
+ ELE + E L +L E Q +QE +AL+Q + ++ + + +++
Sbjct: 2452 IAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQ 2511
Query: 82 QNDQLQD-YRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELA 140
+ +L+ ++ + +AQQL EEQ+RQ R+ + E +R + + +E ++
Sbjct: 2512 EKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASME-EARRRQHEAEEGVRRKQ 2570
Query: 141 PIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREK 180
+L + Q R QQ + +AE N ++L +L E+
Sbjct: 2571 --EELQQLEQQR---RQQEELLAEEN-QRLREQLQLLEEQ 2604
>AY480048-1|AAR95681.1| 4515|Homo sapiens plectin 7 protein.
Length = 4515
Score = 55.2 bits (127), Expect = 4e-07
Identities = 72/378 (19%), Positives = 160/378 (42%), Gaps = 14/378 (3%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTL 78
+ +E Q L++ + + L + E+A E V R EE + L+
Sbjct: 2029 KEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQS 2088
Query: 79 MKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQE 138
+EQ + + ++ E++ + R + + E+++ K ++ L++
Sbjct: 2089 AEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQ 2148
Query: 139 LAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYL-VTTM 197
A + L +++L++ + + + ++L E A + + L+S+ + + +
Sbjct: 2149 KAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEEL 2208
Query: 198 TLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAE 257
+ + + ++++ I R +KD T L + K ++ E A R+ QLAE
Sbjct: 2209 SKLKARIEAENRALILR-DKDNTQRFLQEEAEK-MKQVAEEAARLSVAAQEAARLRQLAE 2266
Query: 258 NNISLKSEI--ERLKASVIRTEESA-LANEKRLQEKMHECAQLGGELDRTRDEASRALQR 314
+++ + + + LK + +E+ L E L ++ E AQ + R +++ + Q+
Sbjct: 2267 EDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQ--EQARRLQEDKEQMAQQ 2324
Query: 315 AHEQTETVRKCLQT-TVAELERQLAASR-----AQVSTAEKEREELKNRLHWQMKRLTEN 368
E+T+ ++ L+ +LE A R A++S A+ EE R Q + + E
Sbjct: 2325 LAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEK 2384
Query: 369 FEQAQLRILGLQTQVQSL 386
+ +L T VQ+L
Sbjct: 2385 LHRTELATQEKVTLVQTL 2402
Score = 48.0 bits (109), Expect = 6e-05
Identities = 63/332 (18%), Positives = 137/332 (41%), Gaps = 16/332 (4%)
Query: 49 EQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXX 108
EQ Q+ V R EE D + L+ E+ +L+ + + + VEE+
Sbjct: 2143 EQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVR 2202
Query: 109 XXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAE 168
+++ +I E + + L+ ++ Q L+ ++K + A A+
Sbjct: 2203 VQMEELSKLKARIEAENRALILRDKDNTQRF------LQEEAEKMKQVAEEAARLSVAAQ 2256
Query: 169 QLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNS 228
+ AR A E + R L L M QE ++++E+ + K+
Sbjct: 2257 EAARLRQLAEEDLAQQ-RALAEKMLKEKMQAVQEATRLKAEAELLQQQKE-LAQEQARRL 2314
Query: 229 LKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQ 288
+ E+ ++ +E Q + + + + + +E ERLK V + E+ Q
Sbjct: 2315 QEDKEQMAQQLAEETQG--FQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQ 2372
Query: 289 EKMHECAQLGGELDRT----RDEAS--RALQRAHEQTETVRKCLQTTVAELERQLAASRA 342
+ ++G +L RT +++ + + L+ +Q++ + L+ +AELER+ +
Sbjct: 2373 RFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQ 2432
Query: 343 QVSTAEKEREELKNRLHWQMKRLTENFEQAQL 374
+ + + EE++ Q+ + T+ +Q+ L
Sbjct: 2433 EAKLLQLKSEEMQTVQQEQLLQETQALQQSFL 2464
Score = 46.8 bits (106), Expect = 1e-04
Identities = 76/366 (20%), Positives = 145/366 (39%), Gaps = 13/366 (3%)
Query: 29 ELEMKFEGLATHTNMLMGSKEQAFEQ-EVNVRALKQCYREAREEIDELRTLMKEQNDQLQ 87
+L + L T T+ + + + E R +Q E RE + E+ +++Q QL
Sbjct: 1286 DLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQR-QLA 1344
Query: 88 DYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDL-L 146
+ + QA+ E + ++ E+ ++ Q+ K QE+LQ+L + +
Sbjct: 1345 E---AHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEI 1401
Query: 147 KATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFG 206
+A + + A++++ E + +L + L +L Q+
Sbjct: 1402 QAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQ 1461
Query: 207 QSQSEIGRGNKDQTVHVLLHN-SLKPPEKPPERGGDEKQMAL--LNQRISQLAENNISLK 263
+ + R +D++ L K EKQ AL L + Q E L+
Sbjct: 1462 EEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLR 1521
Query: 264 -SEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETV 322
+E+ER + + E + + E LQ K A+ +L+R+ E A+ + E+ E
Sbjct: 1522 QAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAE-- 1579
Query: 323 RKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQLRILGLQTQ 382
R+ Q AE R+ A R K E L+ RL + ++ QA+ + +
Sbjct: 1580 RRAQQQAEAERARE-EAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAE 1638
Query: 383 VQSLRR 388
++ RR
Sbjct: 1639 REARRR 1644
Score = 46.4 bits (105), Expect = 2e-04
Identities = 80/375 (21%), Positives = 147/375 (39%), Gaps = 32/375 (8%)
Query: 17 RCQHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELR 76
R + R Q R+L++ E A + K AF + + L+Q ++ + +D+LR
Sbjct: 1991 RLRERAEQESARQLQLAQE--AAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLR 2048
Query: 77 TLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKL 136
+ ++ +QA++ + RRQ E +R+K +E+
Sbjct: 2049 GEAEAARRAAEEAEEARVQAEREAAQSRRQVE---------------EAERLKQSAEEQA 2093
Query: 137 QELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTT 196
Q A +A +L+ + +A AEQ A A + + + L
Sbjct: 2094 QARAQ----AQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQK 2149
Query: 197 MTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLA 256
+ QE + Q E K+ L + E +R E+++ + ++ +L+
Sbjct: 2150 AQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELS 2209
Query: 257 ENNISLKSEIE-RLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRA 315
+ LK+ IE +A ++R +++ + EKM + A+ L EA+R Q A
Sbjct: 2210 K----LKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLA 2265
Query: 316 HEQTETVRKCLQTTVAELERQLAASRAQVSTAEKE-REELKNRLHWQMKRLTENFEQAQL 374
E R + + E+ A A AE E ++ K Q +RL E+ EQ
Sbjct: 2266 EEDLAQQRALAEKMLK--EKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQ 2323
Query: 375 RILGLQTQVQSLRRT 389
+ L + Q +RT
Sbjct: 2324 Q---LAEETQGFQRT 2335
Score = 46.4 bits (105), Expect = 2e-04
Identities = 74/345 (21%), Positives = 147/345 (42%), Gaps = 20/345 (5%)
Query: 21 RETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRAL-KQCYREAREEIDELRTLM 79
+E K++++ + L+ ++ A E RAL ++ +E + + E L
Sbjct: 2235 QEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLK 2294
Query: 80 KEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQEL 139
E Q + QA++L E++ + + E QR +L+ + + L
Sbjct: 2295 AEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQR-QLEMSAEAERL 2353
Query: 140 A-PIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMT 198
+ ++ +A +DAQ+ + AE E+L R +EKV + +L + +
Sbjct: 2354 KLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLV----QTLEIQRQQS 2409
Query: 199 LTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQ--LA 256
+ ++ +E+ R K++ LK E + ++Q+ Q + Q L+
Sbjct: 2410 DHDAERLREAIAELER-EKEKLQQEAKLLQLKSEEMQTVQ---QEQLLQETQALQQSFLS 2465
Query: 257 ENNISLKSE--IERLKASVIRTEESALANEKRL-QEKMHECAQLGGELDRTRDEASRALQ 313
E + L+ E IE+ KA + + + +A ++L +E+ + Q+ E R A +
Sbjct: 2466 EKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARR 2525
Query: 314 RAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRL 358
R HE E VR+ Q + +LE+Q R Q +E + L+ +L
Sbjct: 2526 RQHEAEEGVRR-KQEELQQLEQQ---RRQQEELLAEENQRLREQL 2566
Score = 38.3 bits (85), Expect = 0.049
Identities = 89/407 (21%), Positives = 148/407 (36%), Gaps = 45/407 (11%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKEQA---FEQEVNVRALKQCYRE-----ARE 70
Q R Q +L++L E + E++ E+E+ V L+ E A
Sbjct: 1382 QKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEG 1441
Query: 71 EIDELRTLMKE---QNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQR 127
E+ LR +E Q Q Q+ + + Q +++RQ + + E QR
Sbjct: 1442 ELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQR 1501
Query: 128 VKLKFQE-KLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAE-QLARELNCAREKVVHIF 185
+E +LQ L +A R + Q A A+ +AE +L + EK +
Sbjct: 1502 ALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLE 1561
Query: 186 RYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKD--------------------QTVHVLL 225
R L ++ + + Q Q+E R ++ Q V
Sbjct: 1562 RSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQ 1621
Query: 226 HNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEK 285
SL E ++ E++ + Q + E+E+ + T + LA E+
Sbjct: 1622 QKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQ 1681
Query: 286 RLQEKMHECAQ-------LGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLA 338
L E Q L EL R + EA+ A Q+ E + K AE+E LA
Sbjct: 1682 ELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVR----AEMEVLLA 1737
Query: 339 ASRAQVSTAEKEREELKNRLHWQMKRLTENFEQ-AQLRILGLQTQVQ 384
+ + E+ K RL + R E E+ A+LR L + + Q
Sbjct: 1738 SKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQ 1784
Score = 38.3 bits (85), Expect = 0.049
Identities = 31/134 (23%), Positives = 57/134 (42%), Gaps = 3/134 (2%)
Query: 47 SKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQ 106
+K Q +E R +Q +E + + + + Q++ + R K + QQL +++R+Q
Sbjct: 2493 AKAQQLREEQQ-RQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQ 2551
Query: 107 XXXXXXXNTRISEQINL--EIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAE 164
N R+ EQ+ L E R L E++ D A+A E
Sbjct: 2552 EELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPE 2611
Query: 165 HNAEQLARELNCAR 178
H+ + L R+++ R
Sbjct: 2612 HSFDGLRRKVSAQR 2625
Score = 37.1 bits (82), Expect = 0.11
Identities = 75/390 (19%), Positives = 158/390 (40%), Gaps = 30/390 (7%)
Query: 17 RCQHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELR 76
R + + + +R+ E+ + L + G+ +Q E + L R E+ ++ R
Sbjct: 1642 RRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRL----RAETEQGEQQR 1697
Query: 77 TLMKEQNDQLQDYRVKYLQAQQLVEEQ----RRQXXXXXXXNTRISEQINLEIQRVKLKF 132
L++E+ +LQ Q +Q +E + R + R E+ ++ K +
Sbjct: 1698 QLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRL 1757
Query: 133 QEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLY 192
+ + + + + ++A++ + +AE +A + E E+V + L ++
Sbjct: 1758 EAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEA----ERV--LAEKLAAIG 1811
Query: 193 LVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGD-EKQMALLN-- 249
T + E + ++E R + L+ E+ + D E+++A L
Sbjct: 1812 EATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLE--EQAAQHKADIEERLAQLRKA 1869
Query: 250 -----QRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRT 304
+R L E+ + + ++E ++ + E A A + L+ ++ + R+
Sbjct: 1870 SDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRS 1929
Query: 305 RD----EASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHW 360
++ EA+R Q A E+ R+ + L + A+R Q A +E E LK ++
Sbjct: 1930 KEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAAR-QRKAALEEVERLKAKVE- 1987
Query: 361 QMKRLTENFEQAQLRILGLQTQVQSLRRTA 390
+ +RL E EQ R L L + R A
Sbjct: 1988 EARRLRERAEQESARQLQLAQEAAQKRLQA 2017
Score = 36.7 bits (81), Expect = 0.15
Identities = 73/350 (20%), Positives = 133/350 (38%), Gaps = 18/350 (5%)
Query: 29 ELEMKFEGLATHTNMLMGSKEQAFEQEVNVRAL----KQCYREAREEIDELRTLMKEQND 84
ELE++ + ++ + SKEQA + R L ++ REA E + + +E
Sbjct: 1911 ELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAAR 1970
Query: 85 QLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPD 144
Q + + + + VEE RR + R Q+ E + +L+ +EK A +
Sbjct: 1971 QRKAALEEVERLKAKVEEARRLRERAEQESAR-QLQLAQEAAQKRLQAEEKAHAFA-VQQ 2028
Query: 145 LLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDL 204
+ Q L+ Q AE R A E V R + + + +
Sbjct: 2029 KEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQ----SRRQVEEAER 2084
Query: 205 FGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQL-AENNISLK 263
QS E + K E+ R +Q AL ++ + E +
Sbjct: 2085 LKQSAEEQAQARAQ--AQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFA 2142
Query: 264 SEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVR 323
+ R KA V E+ +L+E H+ L EL R + EA+ A R Q E
Sbjct: 2143 EQTLRQKAQV---EQELTTLRLQLEETDHQKNLLDEELQRLKAEATEA-ARQRSQVEEEL 2198
Query: 324 KCLQTTVAELERQLAASRAQ-VSTAEKEREELKNRLHWQMKRLTENFEQA 372
++ + EL + A A+ + ++++ + L + +++ + E+A
Sbjct: 2199 FSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEA 2248
Score = 34.7 bits (76), Expect = 0.60
Identities = 38/160 (23%), Positives = 76/160 (47%), Gaps = 13/160 (8%)
Query: 27 LRELEMKFEGLATHTNMLMGSKE--QAFEQEV---NVRALKQCYREAREEIDELRTLMKE 81
+ ELE + E L +L E Q +QE +AL+Q + ++ + + +++
Sbjct: 2420 IAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQ 2479
Query: 82 QNDQLQD-YRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELA 140
+ +L+ ++ + +AQQL EEQ+RQ R+ + E +R + + +E ++
Sbjct: 2480 EKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASME-EARRRQHEAEEGVRRKQ 2538
Query: 141 PIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREK 180
+L + Q R QQ + +AE N ++L +L E+
Sbjct: 2539 --EELQQLEQQR---RQQEELLAEEN-QRLREQLQLLEEQ 2572
>AY480047-1|AAR95680.1| 4684|Homo sapiens plectin 6 protein.
Length = 4684
Score = 55.2 bits (127), Expect = 4e-07
Identities = 72/378 (19%), Positives = 160/378 (42%), Gaps = 14/378 (3%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTL 78
+ +E Q L++ + + L + E+A E V R EE + L+
Sbjct: 2198 KEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQS 2257
Query: 79 MKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQE 138
+EQ + + ++ E++ + R + + E+++ K ++ L++
Sbjct: 2258 AEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQ 2317
Query: 139 LAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYL-VTTM 197
A + L +++L++ + + + ++L E A + + L+S+ + + +
Sbjct: 2318 KAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEEL 2377
Query: 198 TLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAE 257
+ + + ++++ I R +KD T L + K ++ E A R+ QLAE
Sbjct: 2378 SKLKARIEAENRALILR-DKDNTQRFLQEEAEK-MKQVAEEAARLSVAAQEAARLRQLAE 2435
Query: 258 NNISLKSEI--ERLKASVIRTEESA-LANEKRLQEKMHECAQLGGELDRTRDEASRALQR 314
+++ + + + LK + +E+ L E L ++ E AQ + R +++ + Q+
Sbjct: 2436 EDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQ--EQARRLQEDKEQMAQQ 2493
Query: 315 AHEQTETVRKCLQT-TVAELERQLAASR-----AQVSTAEKEREELKNRLHWQMKRLTEN 368
E+T+ ++ L+ +LE A R A++S A+ EE R Q + + E
Sbjct: 2494 LAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEK 2553
Query: 369 FEQAQLRILGLQTQVQSL 386
+ +L T VQ+L
Sbjct: 2554 LHRTELATQEKVTLVQTL 2571
Score = 48.0 bits (109), Expect = 6e-05
Identities = 63/332 (18%), Positives = 137/332 (41%), Gaps = 16/332 (4%)
Query: 49 EQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXX 108
EQ Q+ V R EE D + L+ E+ +L+ + + + VEE+
Sbjct: 2312 EQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVR 2371
Query: 109 XXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAE 168
+++ +I E + + L+ ++ Q L+ ++K + A A+
Sbjct: 2372 VQMEELSKLKARIEAENRALILRDKDNTQRF------LQEEAEKMKQVAEEAARLSVAAQ 2425
Query: 169 QLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNS 228
+ AR A E + R L L M QE ++++E+ + K+
Sbjct: 2426 EAARLRQLAEEDLAQQ-RALAEKMLKEKMQAVQEATRLKAEAELLQQQKE-LAQEQARRL 2483
Query: 229 LKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQ 288
+ E+ ++ +E Q + + + + + +E ERLK V + E+ Q
Sbjct: 2484 QEDKEQMAQQLAEETQG--FQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQ 2541
Query: 289 EKMHECAQLGGELDRT----RDEAS--RALQRAHEQTETVRKCLQTTVAELERQLAASRA 342
+ ++G +L RT +++ + + L+ +Q++ + L+ +AELER+ +
Sbjct: 2542 RFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQ 2601
Query: 343 QVSTAEKEREELKNRLHWQMKRLTENFEQAQL 374
+ + + EE++ Q+ + T+ +Q+ L
Sbjct: 2602 EAKLLQLKSEEMQTVQQEQLLQETQALQQSFL 2633
Score = 46.8 bits (106), Expect = 1e-04
Identities = 76/366 (20%), Positives = 145/366 (39%), Gaps = 13/366 (3%)
Query: 29 ELEMKFEGLATHTNMLMGSKEQAFEQ-EVNVRALKQCYREAREEIDELRTLMKEQNDQLQ 87
+L + L T T+ + + + E R +Q E RE + E+ +++Q QL
Sbjct: 1455 DLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQR-QLA 1513
Query: 88 DYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDL-L 146
+ + QA+ E + ++ E+ ++ Q+ K QE+LQ+L + +
Sbjct: 1514 E---AHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEI 1570
Query: 147 KATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFG 206
+A + + A++++ E + +L + L +L Q+
Sbjct: 1571 QAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQ 1630
Query: 207 QSQSEIGRGNKDQTVHVLLHN-SLKPPEKPPERGGDEKQMAL--LNQRISQLAENNISLK 263
+ + R +D++ L K EKQ AL L + Q E L+
Sbjct: 1631 EEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLR 1690
Query: 264 -SEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETV 322
+E+ER + + E + + E LQ K A+ +L+R+ E A+ + E+ E
Sbjct: 1691 QAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAE-- 1748
Query: 323 RKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQLRILGLQTQ 382
R+ Q AE R+ A R K E L+ RL + ++ QA+ + +
Sbjct: 1749 RRAQQQAEAERARE-EAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAE 1807
Query: 383 VQSLRR 388
++ RR
Sbjct: 1808 REARRR 1813
Score = 46.4 bits (105), Expect = 2e-04
Identities = 80/375 (21%), Positives = 147/375 (39%), Gaps = 32/375 (8%)
Query: 17 RCQHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELR 76
R + R Q R+L++ E A + K AF + + L+Q ++ + +D+LR
Sbjct: 2160 RLRERAEQESARQLQLAQE--AAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLR 2217
Query: 77 TLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKL 136
+ ++ +QA++ + RRQ E +R+K +E+
Sbjct: 2218 GEAEAARRAAEEAEEARVQAEREAAQSRRQVE---------------EAERLKQSAEEQA 2262
Query: 137 QELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTT 196
Q A +A +L+ + +A AEQ A A + + + L
Sbjct: 2263 QARAQ----AQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQK 2318
Query: 197 MTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLA 256
+ QE + Q E K+ L + E +R E+++ + ++ +L+
Sbjct: 2319 AQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELS 2378
Query: 257 ENNISLKSEIE-RLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRA 315
+ LK+ IE +A ++R +++ + EKM + A+ L EA+R Q A
Sbjct: 2379 K----LKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLA 2434
Query: 316 HEQTETVRKCLQTTVAELERQLAASRAQVSTAEKE-REELKNRLHWQMKRLTENFEQAQL 374
E R + + E+ A A AE E ++ K Q +RL E+ EQ
Sbjct: 2435 EEDLAQQRALAEKMLK--EKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQ 2492
Query: 375 RILGLQTQVQSLRRT 389
+ L + Q +RT
Sbjct: 2493 Q---LAEETQGFQRT 2504
Score = 46.4 bits (105), Expect = 2e-04
Identities = 74/345 (21%), Positives = 147/345 (42%), Gaps = 20/345 (5%)
Query: 21 RETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRAL-KQCYREAREEIDELRTLM 79
+E K++++ + L+ ++ A E RAL ++ +E + + E L
Sbjct: 2404 QEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLK 2463
Query: 80 KEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQEL 139
E Q + QA++L E++ + + E QR +L+ + + L
Sbjct: 2464 AEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQR-QLEMSAEAERL 2522
Query: 140 A-PIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMT 198
+ ++ +A +DAQ+ + AE E+L R +EKV + +L + +
Sbjct: 2523 KLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLV----QTLEIQRQQS 2578
Query: 199 LTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQ--LA 256
+ ++ +E+ R K++ LK E + ++Q+ Q + Q L+
Sbjct: 2579 DHDAERLREAIAELER-EKEKLQQEAKLLQLKSEEMQTVQ---QEQLLQETQALQQSFLS 2634
Query: 257 ENNISLKSE--IERLKASVIRTEESALANEKRL-QEKMHECAQLGGELDRTRDEASRALQ 313
E + L+ E IE+ KA + + + +A ++L +E+ + Q+ E R A +
Sbjct: 2635 EKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARR 2694
Query: 314 RAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRL 358
R HE E VR+ Q + +LE+Q R Q +E + L+ +L
Sbjct: 2695 RQHEAEEGVRR-KQEELQQLEQQ---RRQQEELLAEENQRLREQL 2735
Score = 38.3 bits (85), Expect = 0.049
Identities = 89/407 (21%), Positives = 148/407 (36%), Gaps = 45/407 (11%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKEQA---FEQEVNVRALKQCYRE-----ARE 70
Q R Q +L++L E + E++ E+E+ V L+ E A
Sbjct: 1551 QKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEG 1610
Query: 71 EIDELRTLMKE---QNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQR 127
E+ LR +E Q Q Q+ + + Q +++RQ + + E QR
Sbjct: 1611 ELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQR 1670
Query: 128 VKLKFQE-KLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAE-QLARELNCAREKVVHIF 185
+E +LQ L +A R + Q A A+ +AE +L + EK +
Sbjct: 1671 ALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLE 1730
Query: 186 RYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKD--------------------QTVHVLL 225
R L ++ + + Q Q+E R ++ Q V
Sbjct: 1731 RSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQ 1790
Query: 226 HNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEK 285
SL E ++ E++ + Q + E+E+ + T + LA E+
Sbjct: 1791 QKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQ 1850
Query: 286 RLQEKMHECAQ-------LGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLA 338
L E Q L EL R + EA+ A Q+ E + K AE+E LA
Sbjct: 1851 ELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVR----AEMEVLLA 1906
Query: 339 ASRAQVSTAEKEREELKNRLHWQMKRLTENFEQ-AQLRILGLQTQVQ 384
+ + E+ K RL + R E E+ A+LR L + + Q
Sbjct: 1907 SKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQ 1953
Score = 38.3 bits (85), Expect = 0.049
Identities = 31/134 (23%), Positives = 57/134 (42%), Gaps = 3/134 (2%)
Query: 47 SKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQ 106
+K Q +E R +Q +E + + + + Q++ + R K + QQL +++R+Q
Sbjct: 2662 AKAQQLREEQQ-RQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQ 2720
Query: 107 XXXXXXXNTRISEQINL--EIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAE 164
N R+ EQ+ L E R L E++ D A+A E
Sbjct: 2721 EELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPE 2780
Query: 165 HNAEQLARELNCAR 178
H+ + L R+++ R
Sbjct: 2781 HSFDGLRRKVSAQR 2794
Score = 37.1 bits (82), Expect = 0.11
Identities = 75/390 (19%), Positives = 158/390 (40%), Gaps = 30/390 (7%)
Query: 17 RCQHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELR 76
R + + + +R+ E+ + L + G+ +Q E + L R E+ ++ R
Sbjct: 1811 RRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRL----RAETEQGEQQR 1866
Query: 77 TLMKEQNDQLQDYRVKYLQAQQLVEEQ----RRQXXXXXXXNTRISEQINLEIQRVKLKF 132
L++E+ +LQ Q +Q +E + R + R E+ ++ K +
Sbjct: 1867 QLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRL 1926
Query: 133 QEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLY 192
+ + + + + ++A++ + +AE +A + E E+V + L ++
Sbjct: 1927 EAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEA----ERV--LAEKLAAIG 1980
Query: 193 LVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGD-EKQMALLN-- 249
T + E + ++E R + L+ E+ + D E+++A L
Sbjct: 1981 EATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLE--EQAAQHKADIEERLAQLRKA 2038
Query: 250 -----QRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRT 304
+R L E+ + + ++E ++ + E A A + L+ ++ + R+
Sbjct: 2039 SDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRS 2098
Query: 305 RD----EASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHW 360
++ EA+R Q A E+ R+ + L + A+R Q A +E E LK ++
Sbjct: 2099 KEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAAR-QRKAALEEVERLKAKVE- 2156
Query: 361 QMKRLTENFEQAQLRILGLQTQVQSLRRTA 390
+ +RL E EQ R L L + R A
Sbjct: 2157 EARRLRERAEQESARQLQLAQEAAQKRLQA 2186
Score = 36.7 bits (81), Expect = 0.15
Identities = 73/350 (20%), Positives = 133/350 (38%), Gaps = 18/350 (5%)
Query: 29 ELEMKFEGLATHTNMLMGSKEQAFEQEVNVRAL----KQCYREAREEIDELRTLMKEQND 84
ELE++ + ++ + SKEQA + R L ++ REA E + + +E
Sbjct: 2080 ELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAAR 2139
Query: 85 QLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPD 144
Q + + + + VEE RR + R Q+ E + +L+ +EK A +
Sbjct: 2140 QRKAALEEVERLKAKVEEARRLRERAEQESAR-QLQLAQEAAQKRLQAEEKAHAFA-VQQ 2197
Query: 145 LLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDL 204
+ Q L+ Q AE R A E V R + + + +
Sbjct: 2198 KEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQ----SRRQVEEAER 2253
Query: 205 FGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQL-AENNISLK 263
QS E + K E+ R +Q AL ++ + E +
Sbjct: 2254 LKQSAEEQAQARAQ--AQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFA 2311
Query: 264 SEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVR 323
+ R KA V E+ +L+E H+ L EL R + EA+ A R Q E
Sbjct: 2312 EQTLRQKAQV---EQELTTLRLQLEETDHQKNLLDEELQRLKAEATEA-ARQRSQVEEEL 2367
Query: 324 KCLQTTVAELERQLAASRAQ-VSTAEKEREELKNRLHWQMKRLTENFEQA 372
++ + EL + A A+ + ++++ + L + +++ + E+A
Sbjct: 2368 FSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEA 2417
Score = 34.7 bits (76), Expect = 0.60
Identities = 38/160 (23%), Positives = 76/160 (47%), Gaps = 13/160 (8%)
Query: 27 LRELEMKFEGLATHTNMLMGSKE--QAFEQEV---NVRALKQCYREAREEIDELRTLMKE 81
+ ELE + E L +L E Q +QE +AL+Q + ++ + + +++
Sbjct: 2589 IAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQ 2648
Query: 82 QNDQLQD-YRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELA 140
+ +L+ ++ + +AQQL EEQ+RQ R+ + E +R + + +E ++
Sbjct: 2649 EKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASME-EARRRQHEAEEGVRRKQ 2707
Query: 141 PIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREK 180
+L + Q R QQ + +AE N ++L +L E+
Sbjct: 2708 --EELQQLEQQR---RQQEELLAEEN-QRLREQLQLLEEQ 2741
>AY480046-1|AAR95679.1| 4525|Homo sapiens plectin 3 protein.
Length = 4525
Score = 55.2 bits (127), Expect = 4e-07
Identities = 72/378 (19%), Positives = 160/378 (42%), Gaps = 14/378 (3%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTL 78
+ +E Q L++ + + L + E+A E V R EE + L+
Sbjct: 2039 KEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQS 2098
Query: 79 MKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQE 138
+EQ + + ++ E++ + R + + E+++ K ++ L++
Sbjct: 2099 AEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQ 2158
Query: 139 LAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYL-VTTM 197
A + L +++L++ + + + ++L E A + + L+S+ + + +
Sbjct: 2159 KAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEEL 2218
Query: 198 TLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAE 257
+ + + ++++ I R +KD T L + K ++ E A R+ QLAE
Sbjct: 2219 SKLKARIEAENRALILR-DKDNTQRFLQEEAEK-MKQVAEEAARLSVAAQEAARLRQLAE 2276
Query: 258 NNISLKSEI--ERLKASVIRTEESA-LANEKRLQEKMHECAQLGGELDRTRDEASRALQR 314
+++ + + + LK + +E+ L E L ++ E AQ + R +++ + Q+
Sbjct: 2277 EDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQ--EQARRLQEDKEQMAQQ 2334
Query: 315 AHEQTETVRKCLQT-TVAELERQLAASR-----AQVSTAEKEREELKNRLHWQMKRLTEN 368
E+T+ ++ L+ +LE A R A++S A+ EE R Q + + E
Sbjct: 2335 LAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEK 2394
Query: 369 FEQAQLRILGLQTQVQSL 386
+ +L T VQ+L
Sbjct: 2395 LHRTELATQEKVTLVQTL 2412
Score = 48.0 bits (109), Expect = 6e-05
Identities = 63/332 (18%), Positives = 137/332 (41%), Gaps = 16/332 (4%)
Query: 49 EQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXX 108
EQ Q+ V R EE D + L+ E+ +L+ + + + VEE+
Sbjct: 2153 EQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVR 2212
Query: 109 XXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAE 168
+++ +I E + + L+ ++ Q L+ ++K + A A+
Sbjct: 2213 VQMEELSKLKARIEAENRALILRDKDNTQRF------LQEEAEKMKQVAEEAARLSVAAQ 2266
Query: 169 QLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNS 228
+ AR A E + R L L M QE ++++E+ + K+
Sbjct: 2267 EAARLRQLAEEDLAQQ-RALAEKMLKEKMQAVQEATRLKAEAELLQQQKE-LAQEQARRL 2324
Query: 229 LKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQ 288
+ E+ ++ +E Q + + + + + +E ERLK V + E+ Q
Sbjct: 2325 QEDKEQMAQQLAEETQG--FQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQ 2382
Query: 289 EKMHECAQLGGELDRT----RDEAS--RALQRAHEQTETVRKCLQTTVAELERQLAASRA 342
+ ++G +L RT +++ + + L+ +Q++ + L+ +AELER+ +
Sbjct: 2383 RFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQ 2442
Query: 343 QVSTAEKEREELKNRLHWQMKRLTENFEQAQL 374
+ + + EE++ Q+ + T+ +Q+ L
Sbjct: 2443 EAKLLQLKSEEMQTVQQEQLLQETQALQQSFL 2474
Score = 46.8 bits (106), Expect = 1e-04
Identities = 76/366 (20%), Positives = 145/366 (39%), Gaps = 13/366 (3%)
Query: 29 ELEMKFEGLATHTNMLMGSKEQAFEQ-EVNVRALKQCYREAREEIDELRTLMKEQNDQLQ 87
+L + L T T+ + + + E R +Q E RE + E+ +++Q QL
Sbjct: 1296 DLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQR-QLA 1354
Query: 88 DYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDL-L 146
+ + QA+ E + ++ E+ ++ Q+ K QE+LQ+L + +
Sbjct: 1355 E---AHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEI 1411
Query: 147 KATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFG 206
+A + + A++++ E + +L + L +L Q+
Sbjct: 1412 QAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQ 1471
Query: 207 QSQSEIGRGNKDQTVHVLLHN-SLKPPEKPPERGGDEKQMAL--LNQRISQLAENNISLK 263
+ + R +D++ L K EKQ AL L + Q E L+
Sbjct: 1472 EEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLR 1531
Query: 264 -SEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETV 322
+E+ER + + E + + E LQ K A+ +L+R+ E A+ + E+ E
Sbjct: 1532 QAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAE-- 1589
Query: 323 RKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQLRILGLQTQ 382
R+ Q AE R+ A R K E L+ RL + ++ QA+ + +
Sbjct: 1590 RRAQQQAEAERARE-EAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAE 1648
Query: 383 VQSLRR 388
++ RR
Sbjct: 1649 REARRR 1654
Score = 46.4 bits (105), Expect = 2e-04
Identities = 80/375 (21%), Positives = 147/375 (39%), Gaps = 32/375 (8%)
Query: 17 RCQHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELR 76
R + R Q R+L++ E A + K AF + + L+Q ++ + +D+LR
Sbjct: 2001 RLRERAEQESARQLQLAQE--AAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLR 2058
Query: 77 TLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKL 136
+ ++ +QA++ + RRQ E +R+K +E+
Sbjct: 2059 GEAEAARRAAEEAEEARVQAEREAAQSRRQVE---------------EAERLKQSAEEQA 2103
Query: 137 QELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTT 196
Q A +A +L+ + +A AEQ A A + + + L
Sbjct: 2104 QARAQ----AQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQK 2159
Query: 197 MTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLA 256
+ QE + Q E K+ L + E +R E+++ + ++ +L+
Sbjct: 2160 AQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELS 2219
Query: 257 ENNISLKSEIE-RLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRA 315
+ LK+ IE +A ++R +++ + EKM + A+ L EA+R Q A
Sbjct: 2220 K----LKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLA 2275
Query: 316 HEQTETVRKCLQTTVAELERQLAASRAQVSTAEKE-REELKNRLHWQMKRLTENFEQAQL 374
E R + + E+ A A AE E ++ K Q +RL E+ EQ
Sbjct: 2276 EEDLAQQRALAEKMLK--EKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQ 2333
Query: 375 RILGLQTQVQSLRRT 389
+ L + Q +RT
Sbjct: 2334 Q---LAEETQGFQRT 2345
Score = 46.4 bits (105), Expect = 2e-04
Identities = 74/345 (21%), Positives = 147/345 (42%), Gaps = 20/345 (5%)
Query: 21 RETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRAL-KQCYREAREEIDELRTLM 79
+E K++++ + L+ ++ A E RAL ++ +E + + E L
Sbjct: 2245 QEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLK 2304
Query: 80 KEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQEL 139
E Q + QA++L E++ + + E QR +L+ + + L
Sbjct: 2305 AEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQR-QLEMSAEAERL 2363
Query: 140 A-PIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMT 198
+ ++ +A +DAQ+ + AE E+L R +EKV + +L + +
Sbjct: 2364 KLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLV----QTLEIQRQQS 2419
Query: 199 LTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQ--LA 256
+ ++ +E+ R K++ LK E + ++Q+ Q + Q L+
Sbjct: 2420 DHDAERLREAIAELER-EKEKLQQEAKLLQLKSEEMQTVQ---QEQLLQETQALQQSFLS 2475
Query: 257 ENNISLKSE--IERLKASVIRTEESALANEKRL-QEKMHECAQLGGELDRTRDEASRALQ 313
E + L+ E IE+ KA + + + +A ++L +E+ + Q+ E R A +
Sbjct: 2476 EKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARR 2535
Query: 314 RAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRL 358
R HE E VR+ Q + +LE+Q R Q +E + L+ +L
Sbjct: 2536 RQHEAEEGVRR-KQEELQQLEQQ---RRQQEELLAEENQRLREQL 2576
Score = 38.3 bits (85), Expect = 0.049
Identities = 89/407 (21%), Positives = 148/407 (36%), Gaps = 45/407 (11%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKEQA---FEQEVNVRALKQCYRE-----ARE 70
Q R Q +L++L E + E++ E+E+ V L+ E A
Sbjct: 1392 QKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEG 1451
Query: 71 EIDELRTLMKE---QNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQR 127
E+ LR +E Q Q Q+ + + Q +++RQ + + E QR
Sbjct: 1452 ELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQR 1511
Query: 128 VKLKFQE-KLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAE-QLARELNCAREKVVHIF 185
+E +LQ L +A R + Q A A+ +AE +L + EK +
Sbjct: 1512 ALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLE 1571
Query: 186 RYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKD--------------------QTVHVLL 225
R L ++ + + Q Q+E R ++ Q V
Sbjct: 1572 RSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQ 1631
Query: 226 HNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEK 285
SL E ++ E++ + Q + E+E+ + T + LA E+
Sbjct: 1632 QKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQ 1691
Query: 286 RLQEKMHECAQ-------LGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLA 338
L E Q L EL R + EA+ A Q+ E + K AE+E LA
Sbjct: 1692 ELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVR----AEMEVLLA 1747
Query: 339 ASRAQVSTAEKEREELKNRLHWQMKRLTENFEQ-AQLRILGLQTQVQ 384
+ + E+ K RL + R E E+ A+LR L + + Q
Sbjct: 1748 SKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQ 1794
Score = 38.3 bits (85), Expect = 0.049
Identities = 31/134 (23%), Positives = 57/134 (42%), Gaps = 3/134 (2%)
Query: 47 SKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQ 106
+K Q +E R +Q +E + + + + Q++ + R K + QQL +++R+Q
Sbjct: 2503 AKAQQLREEQQ-RQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQ 2561
Query: 107 XXXXXXXNTRISEQINL--EIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAE 164
N R+ EQ+ L E R L E++ D A+A E
Sbjct: 2562 EELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPE 2621
Query: 165 HNAEQLARELNCAR 178
H+ + L R+++ R
Sbjct: 2622 HSFDGLRRKVSAQR 2635
Score = 37.1 bits (82), Expect = 0.11
Identities = 75/390 (19%), Positives = 158/390 (40%), Gaps = 30/390 (7%)
Query: 17 RCQHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELR 76
R + + + +R+ E+ + L + G+ +Q E + L R E+ ++ R
Sbjct: 1652 RRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRL----RAETEQGEQQR 1707
Query: 77 TLMKEQNDQLQDYRVKYLQAQQLVEEQ----RRQXXXXXXXNTRISEQINLEIQRVKLKF 132
L++E+ +LQ Q +Q +E + R + R E+ ++ K +
Sbjct: 1708 QLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRL 1767
Query: 133 QEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLY 192
+ + + + + ++A++ + +AE +A + E E+V + L ++
Sbjct: 1768 EAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEA----ERV--LAEKLAAIG 1821
Query: 193 LVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGD-EKQMALLN-- 249
T + E + ++E R + L+ E+ + D E+++A L
Sbjct: 1822 EATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLE--EQAAQHKADIEERLAQLRKA 1879
Query: 250 -----QRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRT 304
+R L E+ + + ++E ++ + E A A + L+ ++ + R+
Sbjct: 1880 SDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRS 1939
Query: 305 RD----EASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHW 360
++ EA+R Q A E+ R+ + L + A+R Q A +E E LK ++
Sbjct: 1940 KEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAAR-QRKAALEEVERLKAKVE- 1997
Query: 361 QMKRLTENFEQAQLRILGLQTQVQSLRRTA 390
+ +RL E EQ R L L + R A
Sbjct: 1998 EARRLRERAEQESARQLQLAQEAAQKRLQA 2027
Score = 36.7 bits (81), Expect = 0.15
Identities = 73/350 (20%), Positives = 133/350 (38%), Gaps = 18/350 (5%)
Query: 29 ELEMKFEGLATHTNMLMGSKEQAFEQEVNVRAL----KQCYREAREEIDELRTLMKEQND 84
ELE++ + ++ + SKEQA + R L ++ REA E + + +E
Sbjct: 1921 ELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAAR 1980
Query: 85 QLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPD 144
Q + + + + VEE RR + R Q+ E + +L+ +EK A +
Sbjct: 1981 QRKAALEEVERLKAKVEEARRLRERAEQESAR-QLQLAQEAAQKRLQAEEKAHAFA-VQQ 2038
Query: 145 LLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDL 204
+ Q L+ Q AE R A E V R + + + +
Sbjct: 2039 KEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQ----SRRQVEEAER 2094
Query: 205 FGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQL-AENNISLK 263
QS E + K E+ R +Q AL ++ + E +
Sbjct: 2095 LKQSAEEQAQARAQ--AQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFA 2152
Query: 264 SEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVR 323
+ R KA V E+ +L+E H+ L EL R + EA+ A R Q E
Sbjct: 2153 EQTLRQKAQV---EQELTTLRLQLEETDHQKNLLDEELQRLKAEATEA-ARQRSQVEEEL 2208
Query: 324 KCLQTTVAELERQLAASRAQ-VSTAEKEREELKNRLHWQMKRLTENFEQA 372
++ + EL + A A+ + ++++ + L + +++ + E+A
Sbjct: 2209 FSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEA 2258
Score = 34.7 bits (76), Expect = 0.60
Identities = 38/160 (23%), Positives = 76/160 (47%), Gaps = 13/160 (8%)
Query: 27 LRELEMKFEGLATHTNMLMGSKE--QAFEQEV---NVRALKQCYREAREEIDELRTLMKE 81
+ ELE + E L +L E Q +QE +AL+Q + ++ + + +++
Sbjct: 2430 IAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQ 2489
Query: 82 QNDQLQD-YRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELA 140
+ +L+ ++ + +AQQL EEQ+RQ R+ + E +R + + +E ++
Sbjct: 2490 EKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASME-EARRRQHEAEEGVRRKQ 2548
Query: 141 PIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREK 180
+L + Q R QQ + +AE N ++L +L E+
Sbjct: 2549 --EELQQLEQQR---RQQEELLAEEN-QRLREQLQLLEEQ 2582
>AY480045-1|AAR95678.1| 4533|Homo sapiens plectin 2 protein.
Length = 4533
Score = 55.2 bits (127), Expect = 4e-07
Identities = 72/378 (19%), Positives = 160/378 (42%), Gaps = 14/378 (3%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTL 78
+ +E Q L++ + + L + E+A E V R EE + L+
Sbjct: 2047 KEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQS 2106
Query: 79 MKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQE 138
+EQ + + ++ E++ + R + + E+++ K ++ L++
Sbjct: 2107 AEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQ 2166
Query: 139 LAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYL-VTTM 197
A + L +++L++ + + + ++L E A + + L+S+ + + +
Sbjct: 2167 KAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEEL 2226
Query: 198 TLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAE 257
+ + + ++++ I R +KD T L + K ++ E A R+ QLAE
Sbjct: 2227 SKLKARIEAENRALILR-DKDNTQRFLQEEAEK-MKQVAEEAARLSVAAQEAARLRQLAE 2284
Query: 258 NNISLKSEI--ERLKASVIRTEESA-LANEKRLQEKMHECAQLGGELDRTRDEASRALQR 314
+++ + + + LK + +E+ L E L ++ E AQ + R +++ + Q+
Sbjct: 2285 EDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQ--EQARRLQEDKEQMAQQ 2342
Query: 315 AHEQTETVRKCLQT-TVAELERQLAASR-----AQVSTAEKEREELKNRLHWQMKRLTEN 368
E+T+ ++ L+ +LE A R A++S A+ EE R Q + + E
Sbjct: 2343 LAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEK 2402
Query: 369 FEQAQLRILGLQTQVQSL 386
+ +L T VQ+L
Sbjct: 2403 LHRTELATQEKVTLVQTL 2420
Score = 48.0 bits (109), Expect = 6e-05
Identities = 63/332 (18%), Positives = 137/332 (41%), Gaps = 16/332 (4%)
Query: 49 EQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXX 108
EQ Q+ V R EE D + L+ E+ +L+ + + + VEE+
Sbjct: 2161 EQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVR 2220
Query: 109 XXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAE 168
+++ +I E + + L+ ++ Q L+ ++K + A A+
Sbjct: 2221 VQMEELSKLKARIEAENRALILRDKDNTQRF------LQEEAEKMKQVAEEAARLSVAAQ 2274
Query: 169 QLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNS 228
+ AR A E + R L L M QE ++++E+ + K+
Sbjct: 2275 EAARLRQLAEEDLAQQ-RALAEKMLKEKMQAVQEATRLKAEAELLQQQKE-LAQEQARRL 2332
Query: 229 LKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQ 288
+ E+ ++ +E Q + + + + + +E ERLK V + E+ Q
Sbjct: 2333 QEDKEQMAQQLAEETQG--FQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQ 2390
Query: 289 EKMHECAQLGGELDRT----RDEAS--RALQRAHEQTETVRKCLQTTVAELERQLAASRA 342
+ ++G +L RT +++ + + L+ +Q++ + L+ +AELER+ +
Sbjct: 2391 RFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQ 2450
Query: 343 QVSTAEKEREELKNRLHWQMKRLTENFEQAQL 374
+ + + EE++ Q+ + T+ +Q+ L
Sbjct: 2451 EAKLLQLKSEEMQTVQQEQLLQETQALQQSFL 2482
Score = 46.8 bits (106), Expect = 1e-04
Identities = 76/366 (20%), Positives = 145/366 (39%), Gaps = 13/366 (3%)
Query: 29 ELEMKFEGLATHTNMLMGSKEQAFEQ-EVNVRALKQCYREAREEIDELRTLMKEQNDQLQ 87
+L + L T T+ + + + E R +Q E RE + E+ +++Q QL
Sbjct: 1304 DLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQR-QLA 1362
Query: 88 DYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDL-L 146
+ + QA+ E + ++ E+ ++ Q+ K QE+LQ+L + +
Sbjct: 1363 E---AHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEI 1419
Query: 147 KATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFG 206
+A + + A++++ E + +L + L +L Q+
Sbjct: 1420 QAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQ 1479
Query: 207 QSQSEIGRGNKDQTVHVLLHN-SLKPPEKPPERGGDEKQMAL--LNQRISQLAENNISLK 263
+ + R +D++ L K EKQ AL L + Q E L+
Sbjct: 1480 EEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLR 1539
Query: 264 -SEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETV 322
+E+ER + + E + + E LQ K A+ +L+R+ E A+ + E+ E
Sbjct: 1540 QAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAE-- 1597
Query: 323 RKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQLRILGLQTQ 382
R+ Q AE R+ A R K E L+ RL + ++ QA+ + +
Sbjct: 1598 RRAQQQAEAERARE-EAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAE 1656
Query: 383 VQSLRR 388
++ RR
Sbjct: 1657 REARRR 1662
Score = 46.4 bits (105), Expect = 2e-04
Identities = 80/375 (21%), Positives = 147/375 (39%), Gaps = 32/375 (8%)
Query: 17 RCQHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELR 76
R + R Q R+L++ E A + K AF + + L+Q ++ + +D+LR
Sbjct: 2009 RLRERAEQESARQLQLAQE--AAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLR 2066
Query: 77 TLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKL 136
+ ++ +QA++ + RRQ E +R+K +E+
Sbjct: 2067 GEAEAARRAAEEAEEARVQAEREAAQSRRQVE---------------EAERLKQSAEEQA 2111
Query: 137 QELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTT 196
Q A +A +L+ + +A AEQ A A + + + L
Sbjct: 2112 QARAQ----AQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQK 2167
Query: 197 MTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLA 256
+ QE + Q E K+ L + E +R E+++ + ++ +L+
Sbjct: 2168 AQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELS 2227
Query: 257 ENNISLKSEIE-RLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRA 315
+ LK+ IE +A ++R +++ + EKM + A+ L EA+R Q A
Sbjct: 2228 K----LKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLA 2283
Query: 316 HEQTETVRKCLQTTVAELERQLAASRAQVSTAEKE-REELKNRLHWQMKRLTENFEQAQL 374
E R + + E+ A A AE E ++ K Q +RL E+ EQ
Sbjct: 2284 EEDLAQQRALAEKMLK--EKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQ 2341
Query: 375 RILGLQTQVQSLRRT 389
+ L + Q +RT
Sbjct: 2342 Q---LAEETQGFQRT 2353
Score = 46.4 bits (105), Expect = 2e-04
Identities = 74/345 (21%), Positives = 147/345 (42%), Gaps = 20/345 (5%)
Query: 21 RETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRAL-KQCYREAREEIDELRTLM 79
+E K++++ + L+ ++ A E RAL ++ +E + + E L
Sbjct: 2253 QEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLK 2312
Query: 80 KEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQEL 139
E Q + QA++L E++ + + E QR +L+ + + L
Sbjct: 2313 AEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQR-QLEMSAEAERL 2371
Query: 140 A-PIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMT 198
+ ++ +A +DAQ+ + AE E+L R +EKV + +L + +
Sbjct: 2372 KLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLV----QTLEIQRQQS 2427
Query: 199 LTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQ--LA 256
+ ++ +E+ R K++ LK E + ++Q+ Q + Q L+
Sbjct: 2428 DHDAERLREAIAELER-EKEKLQQEAKLLQLKSEEMQTVQ---QEQLLQETQALQQSFLS 2483
Query: 257 ENNISLKSE--IERLKASVIRTEESALANEKRL-QEKMHECAQLGGELDRTRDEASRALQ 313
E + L+ E IE+ KA + + + +A ++L +E+ + Q+ E R A +
Sbjct: 2484 EKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARR 2543
Query: 314 RAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRL 358
R HE E VR+ Q + +LE+Q R Q +E + L+ +L
Sbjct: 2544 RQHEAEEGVRR-KQEELQQLEQQ---RRQQEELLAEENQRLREQL 2584
Score = 38.3 bits (85), Expect = 0.049
Identities = 89/407 (21%), Positives = 148/407 (36%), Gaps = 45/407 (11%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKEQA---FEQEVNVRALKQCYRE-----ARE 70
Q R Q +L++L E + E++ E+E+ V L+ E A
Sbjct: 1400 QKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEG 1459
Query: 71 EIDELRTLMKE---QNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQR 127
E+ LR +E Q Q Q+ + + Q +++RQ + + E QR
Sbjct: 1460 ELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQR 1519
Query: 128 VKLKFQE-KLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAE-QLARELNCAREKVVHIF 185
+E +LQ L +A R + Q A A+ +AE +L + EK +
Sbjct: 1520 ALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLE 1579
Query: 186 RYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKD--------------------QTVHVLL 225
R L ++ + + Q Q+E R ++ Q V
Sbjct: 1580 RSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQ 1639
Query: 226 HNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEK 285
SL E ++ E++ + Q + E+E+ + T + LA E+
Sbjct: 1640 QKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQ 1699
Query: 286 RLQEKMHECAQ-------LGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLA 338
L E Q L EL R + EA+ A Q+ E + K AE+E LA
Sbjct: 1700 ELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVR----AEMEVLLA 1755
Query: 339 ASRAQVSTAEKEREELKNRLHWQMKRLTENFEQ-AQLRILGLQTQVQ 384
+ + E+ K RL + R E E+ A+LR L + + Q
Sbjct: 1756 SKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQ 1802
Score = 38.3 bits (85), Expect = 0.049
Identities = 31/134 (23%), Positives = 57/134 (42%), Gaps = 3/134 (2%)
Query: 47 SKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQ 106
+K Q +E R +Q +E + + + + Q++ + R K + QQL +++R+Q
Sbjct: 2511 AKAQQLREEQQ-RQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQ 2569
Query: 107 XXXXXXXNTRISEQINL--EIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAE 164
N R+ EQ+ L E R L E++ D A+A E
Sbjct: 2570 EELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPE 2629
Query: 165 HNAEQLARELNCAR 178
H+ + L R+++ R
Sbjct: 2630 HSFDGLRRKVSAQR 2643
Score = 37.1 bits (82), Expect = 0.11
Identities = 75/390 (19%), Positives = 158/390 (40%), Gaps = 30/390 (7%)
Query: 17 RCQHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELR 76
R + + + +R+ E+ + L + G+ +Q E + L R E+ ++ R
Sbjct: 1660 RRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRL----RAETEQGEQQR 1715
Query: 77 TLMKEQNDQLQDYRVKYLQAQQLVEEQ----RRQXXXXXXXNTRISEQINLEIQRVKLKF 132
L++E+ +LQ Q +Q +E + R + R E+ ++ K +
Sbjct: 1716 QLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRL 1775
Query: 133 QEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLY 192
+ + + + + ++A++ + +AE +A + E E+V + L ++
Sbjct: 1776 EAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEA----ERV--LAEKLAAIG 1829
Query: 193 LVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGD-EKQMALLN-- 249
T + E + ++E R + L+ E+ + D E+++A L
Sbjct: 1830 EATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLE--EQAAQHKADIEERLAQLRKA 1887
Query: 250 -----QRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRT 304
+R L E+ + + ++E ++ + E A A + L+ ++ + R+
Sbjct: 1888 SDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRS 1947
Query: 305 RD----EASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHW 360
++ EA+R Q A E+ R+ + L + A+R Q A +E E LK ++
Sbjct: 1948 KEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAAR-QRKAALEEVERLKAKVE- 2005
Query: 361 QMKRLTENFEQAQLRILGLQTQVQSLRRTA 390
+ +RL E EQ R L L + R A
Sbjct: 2006 EARRLRERAEQESARQLQLAQEAAQKRLQA 2035
Score = 36.7 bits (81), Expect = 0.15
Identities = 73/350 (20%), Positives = 133/350 (38%), Gaps = 18/350 (5%)
Query: 29 ELEMKFEGLATHTNMLMGSKEQAFEQEVNVRAL----KQCYREAREEIDELRTLMKEQND 84
ELE++ + ++ + SKEQA + R L ++ REA E + + +E
Sbjct: 1929 ELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAAR 1988
Query: 85 QLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPD 144
Q + + + + VEE RR + R Q+ E + +L+ +EK A +
Sbjct: 1989 QRKAALEEVERLKAKVEEARRLRERAEQESAR-QLQLAQEAAQKRLQAEEKAHAFA-VQQ 2046
Query: 145 LLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDL 204
+ Q L+ Q AE R A E V R + + + +
Sbjct: 2047 KEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQ----SRRQVEEAER 2102
Query: 205 FGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQL-AENNISLK 263
QS E + K E+ R +Q AL ++ + E +
Sbjct: 2103 LKQSAEEQAQARAQ--AQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFA 2160
Query: 264 SEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVR 323
+ R KA V E+ +L+E H+ L EL R + EA+ A R Q E
Sbjct: 2161 EQTLRQKAQV---EQELTTLRLQLEETDHQKNLLDEELQRLKAEATEA-ARQRSQVEEEL 2216
Query: 324 KCLQTTVAELERQLAASRAQ-VSTAEKEREELKNRLHWQMKRLTENFEQA 372
++ + EL + A A+ + ++++ + L + +++ + E+A
Sbjct: 2217 FSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEA 2266
Score = 34.7 bits (76), Expect = 0.60
Identities = 38/160 (23%), Positives = 76/160 (47%), Gaps = 13/160 (8%)
Query: 27 LRELEMKFEGLATHTNMLMGSKE--QAFEQEV---NVRALKQCYREAREEIDELRTLMKE 81
+ ELE + E L +L E Q +QE +AL+Q + ++ + + +++
Sbjct: 2438 IAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQ 2497
Query: 82 QNDQLQD-YRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELA 140
+ +L+ ++ + +AQQL EEQ+RQ R+ + E +R + + +E ++
Sbjct: 2498 EKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASME-EARRRQHEAEEGVRRKQ 2556
Query: 141 PIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREK 180
+L + Q R QQ + +AE N ++L +L E+
Sbjct: 2557 --EELQQLEQQR---RQQEELLAEEN-QRLREQLQLLEEQ 2590
>AY480044-1|AAR95677.1| 4574|Homo sapiens plectin 1 protein.
Length = 4574
Score = 55.2 bits (127), Expect = 4e-07
Identities = 72/378 (19%), Positives = 160/378 (42%), Gaps = 14/378 (3%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTL 78
+ +E Q L++ + + L + E+A E V R EE + L+
Sbjct: 2088 KEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQS 2147
Query: 79 MKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQE 138
+EQ + + ++ E++ + R + + E+++ K ++ L++
Sbjct: 2148 AEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQ 2207
Query: 139 LAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYL-VTTM 197
A + L +++L++ + + + ++L E A + + L+S+ + + +
Sbjct: 2208 KAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEEL 2267
Query: 198 TLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAE 257
+ + + ++++ I R +KD T L + K ++ E A R+ QLAE
Sbjct: 2268 SKLKARIEAENRALILR-DKDNTQRFLQEEAEK-MKQVAEEAARLSVAAQEAARLRQLAE 2325
Query: 258 NNISLKSEI--ERLKASVIRTEESA-LANEKRLQEKMHECAQLGGELDRTRDEASRALQR 314
+++ + + + LK + +E+ L E L ++ E AQ + R +++ + Q+
Sbjct: 2326 EDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQ--EQARRLQEDKEQMAQQ 2383
Query: 315 AHEQTETVRKCLQT-TVAELERQLAASR-----AQVSTAEKEREELKNRLHWQMKRLTEN 368
E+T+ ++ L+ +LE A R A++S A+ EE R Q + + E
Sbjct: 2384 LAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEK 2443
Query: 369 FEQAQLRILGLQTQVQSL 386
+ +L T VQ+L
Sbjct: 2444 LHRTELATQEKVTLVQTL 2461
Score = 48.0 bits (109), Expect = 6e-05
Identities = 63/332 (18%), Positives = 137/332 (41%), Gaps = 16/332 (4%)
Query: 49 EQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXX 108
EQ Q+ V R EE D + L+ E+ +L+ + + + VEE+
Sbjct: 2202 EQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVR 2261
Query: 109 XXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAE 168
+++ +I E + + L+ ++ Q L+ ++K + A A+
Sbjct: 2262 VQMEELSKLKARIEAENRALILRDKDNTQRF------LQEEAEKMKQVAEEAARLSVAAQ 2315
Query: 169 QLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNS 228
+ AR A E + R L L M QE ++++E+ + K+
Sbjct: 2316 EAARLRQLAEEDLAQQ-RALAEKMLKEKMQAVQEATRLKAEAELLQQQKE-LAQEQARRL 2373
Query: 229 LKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQ 288
+ E+ ++ +E Q + + + + + +E ERLK V + E+ Q
Sbjct: 2374 QEDKEQMAQQLAEETQG--FQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQ 2431
Query: 289 EKMHECAQLGGELDRT----RDEAS--RALQRAHEQTETVRKCLQTTVAELERQLAASRA 342
+ ++G +L RT +++ + + L+ +Q++ + L+ +AELER+ +
Sbjct: 2432 RFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQ 2491
Query: 343 QVSTAEKEREELKNRLHWQMKRLTENFEQAQL 374
+ + + EE++ Q+ + T+ +Q+ L
Sbjct: 2492 EAKLLQLKSEEMQTVQQEQLLQETQALQQSFL 2523
Score = 46.8 bits (106), Expect = 1e-04
Identities = 76/366 (20%), Positives = 145/366 (39%), Gaps = 13/366 (3%)
Query: 29 ELEMKFEGLATHTNMLMGSKEQAFEQ-EVNVRALKQCYREAREEIDELRTLMKEQNDQLQ 87
+L + L T T+ + + + E R +Q E RE + E+ +++Q QL
Sbjct: 1345 DLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQR-QLA 1403
Query: 88 DYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDL-L 146
+ + QA+ E + ++ E+ ++ Q+ K QE+LQ+L + +
Sbjct: 1404 E---AHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEI 1460
Query: 147 KATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFG 206
+A + + A++++ E + +L + L +L Q+
Sbjct: 1461 QAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQ 1520
Query: 207 QSQSEIGRGNKDQTVHVLLHN-SLKPPEKPPERGGDEKQMAL--LNQRISQLAENNISLK 263
+ + R +D++ L K EKQ AL L + Q E L+
Sbjct: 1521 EEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLR 1580
Query: 264 -SEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETV 322
+E+ER + + E + + E LQ K A+ +L+R+ E A+ + E+ E
Sbjct: 1581 QAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAE-- 1638
Query: 323 RKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQLRILGLQTQ 382
R+ Q AE R+ A R K E L+ RL + ++ QA+ + +
Sbjct: 1639 RRAQQQAEAERARE-EAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAE 1697
Query: 383 VQSLRR 388
++ RR
Sbjct: 1698 REARRR 1703
Score = 46.4 bits (105), Expect = 2e-04
Identities = 80/375 (21%), Positives = 147/375 (39%), Gaps = 32/375 (8%)
Query: 17 RCQHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELR 76
R + R Q R+L++ E A + K AF + + L+Q ++ + +D+LR
Sbjct: 2050 RLRERAEQESARQLQLAQE--AAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLR 2107
Query: 77 TLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKL 136
+ ++ +QA++ + RRQ E +R+K +E+
Sbjct: 2108 GEAEAARRAAEEAEEARVQAEREAAQSRRQVE---------------EAERLKQSAEEQA 2152
Query: 137 QELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTT 196
Q A +A +L+ + +A AEQ A A + + + L
Sbjct: 2153 QARAQ----AQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQK 2208
Query: 197 MTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLA 256
+ QE + Q E K+ L + E +R E+++ + ++ +L+
Sbjct: 2209 AQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELS 2268
Query: 257 ENNISLKSEIE-RLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRA 315
+ LK+ IE +A ++R +++ + EKM + A+ L EA+R Q A
Sbjct: 2269 K----LKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLA 2324
Query: 316 HEQTETVRKCLQTTVAELERQLAASRAQVSTAEKE-REELKNRLHWQMKRLTENFEQAQL 374
E R + + E+ A A AE E ++ K Q +RL E+ EQ
Sbjct: 2325 EEDLAQQRALAEKMLK--EKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQ 2382
Query: 375 RILGLQTQVQSLRRT 389
+ L + Q +RT
Sbjct: 2383 Q---LAEETQGFQRT 2394
Score = 46.4 bits (105), Expect = 2e-04
Identities = 74/345 (21%), Positives = 147/345 (42%), Gaps = 20/345 (5%)
Query: 21 RETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRAL-KQCYREAREEIDELRTLM 79
+E K++++ + L+ ++ A E RAL ++ +E + + E L
Sbjct: 2294 QEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLK 2353
Query: 80 KEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQEL 139
E Q + QA++L E++ + + E QR +L+ + + L
Sbjct: 2354 AEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQR-QLEMSAEAERL 2412
Query: 140 A-PIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMT 198
+ ++ +A +DAQ+ + AE E+L R +EKV + +L + +
Sbjct: 2413 KLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLV----QTLEIQRQQS 2468
Query: 199 LTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQ--LA 256
+ ++ +E+ R K++ LK E + ++Q+ Q + Q L+
Sbjct: 2469 DHDAERLREAIAELER-EKEKLQQEAKLLQLKSEEMQTVQ---QEQLLQETQALQQSFLS 2524
Query: 257 ENNISLKSE--IERLKASVIRTEESALANEKRL-QEKMHECAQLGGELDRTRDEASRALQ 313
E + L+ E IE+ KA + + + +A ++L +E+ + Q+ E R A +
Sbjct: 2525 EKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARR 2584
Query: 314 RAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRL 358
R HE E VR+ Q + +LE+Q R Q +E + L+ +L
Sbjct: 2585 RQHEAEEGVRR-KQEELQQLEQQ---RRQQEELLAEENQRLREQL 2625
Score = 38.3 bits (85), Expect = 0.049
Identities = 89/407 (21%), Positives = 148/407 (36%), Gaps = 45/407 (11%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKEQA---FEQEVNVRALKQCYRE-----ARE 70
Q R Q +L++L E + E++ E+E+ V L+ E A
Sbjct: 1441 QKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEG 1500
Query: 71 EIDELRTLMKE---QNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQR 127
E+ LR +E Q Q Q+ + + Q +++RQ + + E QR
Sbjct: 1501 ELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQR 1560
Query: 128 VKLKFQE-KLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAE-QLARELNCAREKVVHIF 185
+E +LQ L +A R + Q A A+ +AE +L + EK +
Sbjct: 1561 ALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLE 1620
Query: 186 RYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKD--------------------QTVHVLL 225
R L ++ + + Q Q+E R ++ Q V
Sbjct: 1621 RSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQ 1680
Query: 226 HNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEK 285
SL E ++ E++ + Q + E+E+ + T + LA E+
Sbjct: 1681 QKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQ 1740
Query: 286 RLQEKMHECAQ-------LGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLA 338
L E Q L EL R + EA+ A Q+ E + K AE+E LA
Sbjct: 1741 ELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVR----AEMEVLLA 1796
Query: 339 ASRAQVSTAEKEREELKNRLHWQMKRLTENFEQ-AQLRILGLQTQVQ 384
+ + E+ K RL + R E E+ A+LR L + + Q
Sbjct: 1797 SKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQ 1843
Score = 38.3 bits (85), Expect = 0.049
Identities = 31/134 (23%), Positives = 57/134 (42%), Gaps = 3/134 (2%)
Query: 47 SKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQ 106
+K Q +E R +Q +E + + + + Q++ + R K + QQL +++R+Q
Sbjct: 2552 AKAQQLREEQQ-RQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQ 2610
Query: 107 XXXXXXXNTRISEQINL--EIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAE 164
N R+ EQ+ L E R L E++ D A+A E
Sbjct: 2611 EELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPE 2670
Query: 165 HNAEQLARELNCAR 178
H+ + L R+++ R
Sbjct: 2671 HSFDGLRRKVSAQR 2684
Score = 37.1 bits (82), Expect = 0.11
Identities = 75/390 (19%), Positives = 158/390 (40%), Gaps = 30/390 (7%)
Query: 17 RCQHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELR 76
R + + + +R+ E+ + L + G+ +Q E + L R E+ ++ R
Sbjct: 1701 RRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRL----RAETEQGEQQR 1756
Query: 77 TLMKEQNDQLQDYRVKYLQAQQLVEEQ----RRQXXXXXXXNTRISEQINLEIQRVKLKF 132
L++E+ +LQ Q +Q +E + R + R E+ ++ K +
Sbjct: 1757 QLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRL 1816
Query: 133 QEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLY 192
+ + + + + ++A++ + +AE +A + E E+V + L ++
Sbjct: 1817 EAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEA----ERV--LAEKLAAIG 1870
Query: 193 LVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGD-EKQMALLN-- 249
T + E + ++E R + L+ E+ + D E+++A L
Sbjct: 1871 EATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLE--EQAAQHKADIEERLAQLRKA 1928
Query: 250 -----QRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRT 304
+R L E+ + + ++E ++ + E A A + L+ ++ + R+
Sbjct: 1929 SDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRS 1988
Query: 305 RD----EASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHW 360
++ EA+R Q A E+ R+ + L + A+R Q A +E E LK ++
Sbjct: 1989 KEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAAR-QRKAALEEVERLKAKVE- 2046
Query: 361 QMKRLTENFEQAQLRILGLQTQVQSLRRTA 390
+ +RL E EQ R L L + R A
Sbjct: 2047 EARRLRERAEQESARQLQLAQEAAQKRLQA 2076
Score = 36.7 bits (81), Expect = 0.15
Identities = 73/350 (20%), Positives = 133/350 (38%), Gaps = 18/350 (5%)
Query: 29 ELEMKFEGLATHTNMLMGSKEQAFEQEVNVRAL----KQCYREAREEIDELRTLMKEQND 84
ELE++ + ++ + SKEQA + R L ++ REA E + + +E
Sbjct: 1970 ELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAAR 2029
Query: 85 QLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPD 144
Q + + + + VEE RR + R Q+ E + +L+ +EK A +
Sbjct: 2030 QRKAALEEVERLKAKVEEARRLRERAEQESAR-QLQLAQEAAQKRLQAEEKAHAFA-VQQ 2087
Query: 145 LLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDL 204
+ Q L+ Q AE R A E V R + + + +
Sbjct: 2088 KEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQ----SRRQVEEAER 2143
Query: 205 FGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQL-AENNISLK 263
QS E + K E+ R +Q AL ++ + E +
Sbjct: 2144 LKQSAEEQAQARAQ--AQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFA 2201
Query: 264 SEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVR 323
+ R KA V E+ +L+E H+ L EL R + EA+ A R Q E
Sbjct: 2202 EQTLRQKAQV---EQELTTLRLQLEETDHQKNLLDEELQRLKAEATEA-ARQRSQVEEEL 2257
Query: 324 KCLQTTVAELERQLAASRAQ-VSTAEKEREELKNRLHWQMKRLTENFEQA 372
++ + EL + A A+ + ++++ + L + +++ + E+A
Sbjct: 2258 FSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEA 2307
Score = 34.7 bits (76), Expect = 0.60
Identities = 38/160 (23%), Positives = 76/160 (47%), Gaps = 13/160 (8%)
Query: 27 LRELEMKFEGLATHTNMLMGSKE--QAFEQEV---NVRALKQCYREAREEIDELRTLMKE 81
+ ELE + E L +L E Q +QE +AL+Q + ++ + + +++
Sbjct: 2479 IAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQ 2538
Query: 82 QNDQLQD-YRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELA 140
+ +L+ ++ + +AQQL EEQ+RQ R+ + E +R + + +E ++
Sbjct: 2539 EKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASME-EARRRQHEAEEGVRRKQ 2597
Query: 141 PIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREK 180
+L + Q R QQ + +AE N ++L +L E+
Sbjct: 2598 --EELQQLEQQR---RQQEELLAEEN-QRLREQLQLLEEQ 2631
>Z82215-4|CAB05105.1| 1960|Homo sapiens myosin, heavy chain 9,
non-muscle protein.
Length = 1960
Score = 54.8 bits (126), Expect = 5e-07
Identities = 72/390 (18%), Positives = 172/390 (44%), Gaps = 29/390 (7%)
Query: 22 ETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKE 81
E + ELE + T LM SK+ + +V L++ R ++++E++T ++E
Sbjct: 1487 EAMEQKAELERLNKQFRTEMEDLMSSKDDVGK---SVHELEKSKRALEQQVEEMKTQLEE 1543
Query: 82 QNDQLQ---DYRVKY-LQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQ 137
D+LQ D +++ + Q + + R + +Q+ +++ ++ + +++ +
Sbjct: 1544 LEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERK 1603
Query: 138 ELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTM 197
+ + K +M LKD + A N ++ ++L + ++ R L
Sbjct: 1604 QRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMREL------DDT 1657
Query: 198 TLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAE 257
++E++ Q++ + + + L L E+ +R +++ L ++ + +
Sbjct: 1658 RASREEILAQAKENEKKLKSMEAEMIQLQEELAAAER-AKRQAQQERDELADEIANSSGK 1716
Query: 258 NNISLKSEIERLKASVIRTEE--------SALANEKRLQEKMHECAQLGGELDRTRDEAS 309
++L+ E RL+A + + EE + L N+ RL++ + Q+ +L+ R A
Sbjct: 1717 GALALE-EKRRLEARIAQLEEELEEEQGNTELIND-RLKKANLQIDQINTDLNLERSHAQ 1774
Query: 310 RALQRAHEQTETVRKCLQTTVAELERQLAAS-RAQVSTAEKEREELKNRLHWQMKR---L 365
+ + A +Q E K L+ + E+E + + +A ++ E + +L+ +L + K
Sbjct: 1775 KN-ENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAA 1833
Query: 366 TENFEQAQLRILGLQTQVQSLRRTASSTGD 395
+ + + ++ + QV RR A D
Sbjct: 1834 CKQVRRTEKKLKDVLLQVDDERRNAEQYKD 1863
Score = 50.4 bits (115), Expect = 1e-05
Identities = 81/367 (22%), Positives = 155/367 (42%), Gaps = 50/367 (13%)
Query: 26 KLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQ 85
K+RE ++ E T L + Q +++ ++ Q E E +ELR + + +
Sbjct: 856 KVREKQLAAENRLTEMETL---QSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQE 912
Query: 86 LQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDL 145
L++ L+A+ EE+R Q Q N++ +L+ +E ++ + +
Sbjct: 913 LEEI-CHDLEARVEEEEERCQHLQAEKKKM----QQNIQELEEQLEEEESARQKLQLEKV 967
Query: 146 LKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLF 205
T+ +LK ++ Q I E +LA+E +++ T LT+E+
Sbjct: 968 --TTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEF-----------TTNLTEEEEK 1014
Query: 206 GQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSE 265
+S +++ NK + + L L+ EK +R EK L + L++ L+++
Sbjct: 1015 SKSLAKLK--NKHEAMITDLEERLRREEK--QRQELEKTRRKLEGDSTDLSDQIAELQAQ 1070
Query: 266 IERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKC 325
I LK + + EE A R++E E AQ L + R+
Sbjct: 1071 IAELKMQLAKKEEELQAALARVEE---EAAQKNMALKKIRE------------------- 1108
Query: 326 LQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQ--AQLRILGLQTQ- 382
L++ ++EL+ L + RA + AEK++ +L L L + + AQ + + Q
Sbjct: 1109 LESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQE 1168
Query: 383 VQSLRRT 389
V L++T
Sbjct: 1169 VNILKKT 1175
Score = 39.9 bits (89), Expect = 0.016
Identities = 83/392 (21%), Positives = 162/392 (41%), Gaps = 24/392 (6%)
Query: 24 QNKLRELE-MKFEGLATHTNM---LMGSKEQAFEQEVNVRALKQCYREAREEI-DELRTL 78
+N+L E+E ++ + +A + L E E E +RA ++ EEI +L
Sbjct: 865 ENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAE-ELRARLTAKKQELEEICHDLEAR 923
Query: 79 MKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRIS-EQINLEIQRVKLKFQEKLQ 137
++E+ ++ Q + + + QQ ++E Q ++ E++ E + KL+ ++ +
Sbjct: 924 VEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIIL 983
Query: 138 E--LAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVT 195
E + K + R+ + E ++ LA+ N + + L
Sbjct: 984 EDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQR 1043
Query: 196 T-MTLTQEDLFGQSQ--SEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRI 252
+ T+ L G S S+ + Q + + + K E E++ A N +
Sbjct: 1044 QELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMAL 1103
Query: 253 SQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDE--ASR 310
++ E L+S+I L+ + S EK+ ++ E L EL+ T D A +
Sbjct: 1104 KKIRE----LESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQ 1159
Query: 311 ALQRAHEQ-TETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENF 369
L+ EQ ++K L+ E Q+ R + S A EEL +L Q KR+ N
Sbjct: 1160 ELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAV---EELAEQLE-QTKRVKANL 1215
Query: 370 EQAQLRILGLQTQVQSLRRTASSTGDGDGENQ 401
E+A+ + + ++ + + G GD E++
Sbjct: 1216 EKAKQTLENERGELANEVKVLLQ-GKGDSEHK 1246
Score = 39.9 bits (89), Expect = 0.016
Identities = 66/367 (17%), Positives = 149/367 (40%), Gaps = 28/367 (7%)
Query: 19 QHRETQNKLRELEMKF-EGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRT 77
+ ++ + +L+EL++KF EG T + ++ + +V + + ++ + +L
Sbjct: 1246 KRKKVEAQLQELQVKFNEGERVRTELA----DKVTKLQVELDNVTGLLSQSDSKSSKLTK 1301
Query: 78 LMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKL- 136
QLQD Q+L++E+ RQ ++ ++ N ++++ + + K
Sbjct: 1302 DFSALESQLQD-------TQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHN 1354
Query: 137 --QELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLV 194
+++A + + + +++D+ AE +L ++L ++ Y
Sbjct: 1355 LEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVA-AYDKLEK 1413
Query: 195 TTMTLTQE------DLFGQSQSEIGRGNKDQTVHVLLHN----SLKPPEKPPERGGDEKQ 244
T L QE DL Q QS K + LL S K E+ + ++
Sbjct: 1414 TKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEARE 1473
Query: 245 MALLNQRISQLAENNISLKSEIERLKASVIRTE-ESALANEKRLQEKMHECAQLGGELDR 303
+++ E + K+E+ERL RTE E ++++ + + +HE + L++
Sbjct: 1474 KETKALSLARALEEAMEQKAELERLNKQ-FRTEMEDLMSSKDDVGKSVHELEKSKRALEQ 1532
Query: 304 TRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMK 363
+E L+ ++ + L+ A + +++ EE K +L Q++
Sbjct: 1533 QVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVR 1592
Query: 364 RLTENFE 370
+ E
Sbjct: 1593 EMEAELE 1599
Score = 37.9 bits (84), Expect = 0.065
Identities = 69/336 (20%), Positives = 132/336 (39%), Gaps = 32/336 (9%)
Query: 28 RELEMKFEGLATHTNMLMGSKEQAFEQEVNVRA-LKQCYRE---AREEIDELRTLMKEQN 83
++LEM + L H + ++++A +Q ++A +K C RE R +E+ KE
Sbjct: 1613 KKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENE 1672
Query: 84 DQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIP 143
+L+ + +Q Q+ + R ++++I + L +EK
Sbjct: 1673 KKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEK-------- 1724
Query: 144 DLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQED 203
R +A+ AQ E EQ EL R K ++ + L + Q++
Sbjct: 1725 --------RRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKN 1776
Query: 204 LFGQSQSEIGRGNKDQTVHVL-LHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISL 262
+ Q E R NK+ V + + ++K K + L +I+QL E +
Sbjct: 1777 ENARQQLE--RQNKELKVKLQEMEGTVKSKYKA--------SITALEAKIAQLEEQLDNE 1826
Query: 263 KSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETV 322
E + V RTE+ ++ ++ Q + D+ + L+R E+ E
Sbjct: 1827 TKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQ-LKRQLEEAEEE 1885
Query: 323 RKCLQTTVAELERQLAASRAQVSTAEKEREELKNRL 358
+ + +L+R+L + +E LKN+L
Sbjct: 1886 AQRANASRRKLQRELEDATETADAMNREVSSLKNKL 1921
Score = 33.5 bits (73), Expect = 1.4
Identities = 76/359 (21%), Positives = 154/359 (42%), Gaps = 30/359 (8%)
Query: 48 KEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQX 107
+E+A E ++ ++Q + +A EE + EQ +Q + + +A+Q +E +R +
Sbjct: 1177 EEEAKTHEAQIQEMRQKHSQAVEE-------LAEQLEQTKRVKANLEKAKQTLENERGE- 1228
Query: 108 XXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNA 167
++ Q + + + K + +LQEL + + + L D + N
Sbjct: 1229 ---LANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNV 1285
Query: 168 EQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHN 227
L + + K+ F L S L T L QE +++ ++ K + V ++
Sbjct: 1286 TGLLSQSDSKSSKLTKDFSALES-QLQDTQELLQE----ENRQKLSLSTKLKQVEDEKNS 1340
Query: 228 SLKPPEKPPE-RGGDEKQMALLNQRISQL---AENNISLKSEIERLKASVIRTEES-ALA 282
+ E+ E + EKQ+A L+ +++ + E+++ E +K + + E +
Sbjct: 1341 FREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQR 1400
Query: 283 NEKRL--QEKMHEC-AQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAA 339
+E+++ +K+ + +L ELD + Q A E +K +AE E+ ++A
Sbjct: 1401 HEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSAC-NLEKKQKKFDQLLAE-EKTISA 1458
Query: 340 SRAQV-STAEKEREELKNRLHWQMKRLTENFEQ-AQLRILGLQ--TQVQSLRRTASSTG 394
A+ AE E E + + + L E EQ A+L L Q T+++ L + G
Sbjct: 1459 KYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVG 1517
>X69292-1|CAA49154.1| 881|Homo sapiens smooth muscle mysosin heavy
chain protein.
Length = 881
Score = 54.8 bits (126), Expect = 5e-07
Identities = 78/370 (21%), Positives = 156/370 (42%), Gaps = 36/370 (9%)
Query: 29 ELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQ- 87
ELE + L L+ SK+ + NV L++ R +++E++T ++E D+LQ
Sbjct: 410 ELERTNKMLKAEMEDLVSSKDDVGK---NVHELEKSKRALETQMEEMKTQLEELEDELQA 466
Query: 88 --DYRVKY-LQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPD 144
D +++ + Q L + R N Q+ ++ + + +++ ++ A
Sbjct: 467 TEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAA 526
Query: 145 LLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDL 204
K + LKD + A E+ ++L + ++ R L +++++
Sbjct: 527 AKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDA------RASRDEI 580
Query: 205 FGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKS 264
F ++ + + + L L E+ ++ EK+ L + S L+ N +L+
Sbjct: 581 FATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKE-ELAEELASSLSGRN-ALQD 638
Query: 265 EIERLKASVIRTEE-------SALANEKRLQEKMHECAQLGGELDRTR-----DEASRA- 311
E RL+A + + EE + A R+++ + QL EL R +E+SR
Sbjct: 639 EKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESSRQQ 698
Query: 312 LQRA--------HEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMK 363
L+R HE V+ ++T+A LE ++A QV +E++ L + K
Sbjct: 699 LERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDK 758
Query: 364 RLTENFEQAQ 373
+L E Q +
Sbjct: 759 KLKEILLQVE 768
Score = 45.2 bits (102), Expect = 4e-04
Identities = 79/398 (19%), Positives = 162/398 (40%), Gaps = 29/398 (7%)
Query: 22 ETQNKLRELEMKFEGLATHT----NMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRT 77
E + R LE + E + T + L +++ EVN++ALK + + DE
Sbjct: 438 ELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQN- 496
Query: 78 LMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQI-NLEIQRVK-LKFQEK 135
+E+ QLQ +Y + +E++R+Q ++ + +LE+Q +K +E+
Sbjct: 497 --EEKRRQLQRQLHEY---ETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREE 551
Query: 136 -LQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLV 194
+++L + +K Q L+DA+ ++ A++ ++ ++ + L +
Sbjct: 552 AIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERA 611
Query: 195 TTMT-LTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRIS 253
L +E+L + S + N Q L + E+ E ++ M ++ R+
Sbjct: 612 RKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEE--EQGNMEAMSDRVR 669
Query: 254 QLAENNISLKSEIERLKASVIRTEESALANE---KRLQEKMHEC-AQLGGELDRTRDEAS 309
+ + L +E+ +++ + E S E K L+ K+HE + + T
Sbjct: 670 KATQQAEQLSNELATERSTAQKNESSRQQLERQNKELRSKLHEMEGAVKSKFKSTIAALE 729
Query: 310 RALQRAHEQTETVRKCLQTTVAEL---ERQLAASRAQVSTAEKEREELKNRLHW------ 360
+ + EQ E + Q L +++L QV K E+ K +
Sbjct: 730 AKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVK 789
Query: 361 QMKRLTENFEQAQLRILGLQTQVQSLRRTASSTGDGDG 398
Q+KR E E+ RI + ++Q A+ + + G
Sbjct: 790 QLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMG 827
Score = 33.9 bits (74), Expect = 1.1
Identities = 36/160 (22%), Positives = 67/160 (41%), Gaps = 4/160 (2%)
Query: 250 QRISQLAENNISLKS---EIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRD 306
+ I QL + +K E+E +AS +A NEK+ + + QL +L
Sbjct: 551 EAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAER 610
Query: 307 EASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLT 366
+A E E + L A L+ + A+++ E+E EE + + R+
Sbjct: 611 ARKQADLEKEELAEELASSLSGRNA-LQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVR 669
Query: 367 ENFEQAQLRILGLQTQVQSLRRTASSTGDGDGENQECTCK 406
+ +QA+ L T+ + ++ SS + +N+E K
Sbjct: 670 KATQQAEQLSNELATERSTAQKNESSRQQLERQNKELRSK 709
Score = 33.5 bits (73), Expect = 1.4
Identities = 28/137 (20%), Positives = 62/137 (45%), Gaps = 6/137 (4%)
Query: 242 EKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGEL 301
EK+ L+ +++ E + K E+ER + E ++++ + + +HE + L
Sbjct: 389 EKETKALS--LARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRAL 446
Query: 302 DRTRDEASRALQRAHEQ---TETVRKCLQTTVAELERQLAAS-RAQVSTAEKEREELKNR 357
+ +E L+ ++ TE + L+ + L+ Q +A+ E++R +L+ +
Sbjct: 447 ETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQ 506
Query: 358 LHWQMKRLTENFEQAQL 374
LH L + +Q L
Sbjct: 507 LHEYETELEDERKQRAL 523
Score = 31.1 bits (67), Expect = 7.4
Identities = 31/159 (19%), Positives = 69/159 (43%), Gaps = 10/159 (6%)
Query: 238 RGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQL 297
R E+++ +L + + + ++ + E+ + A + L KR + + + Q
Sbjct: 78 RAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQT 137
Query: 298 GGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNR 357
+ + R L +A ++ E +K L+ V EL+ ++ S E+ R EL ++
Sbjct: 138 LEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQ-------SKCSDGERARAELNDK 190
Query: 358 LHW---QMKRLTENFEQAQLRILGLQTQVQSLRRTASST 393
+H +++ +T +A+ + + L V SL T
Sbjct: 191 VHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDT 229
>U30872-1|AAA82935.1| 3113|Homo sapiens mitosin protein.
Length = 3113
Score = 54.8 bits (126), Expect = 5e-07
Identities = 74/367 (20%), Positives = 154/367 (41%), Gaps = 30/367 (8%)
Query: 22 ETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNV-RALKQCYRE----------ARE 70
E +N++ +L + E L + L ++ +++NV +AL+ E +E
Sbjct: 2052 ELENQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQE 2111
Query: 71 EIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKL 130
E+ +LR +++ +++ K L + ++E+ R+ + ++ + + +L
Sbjct: 2112 EVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQEL 2171
Query: 131 KFQEKLQELAPIPDL---LKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRY 187
+ A + L ++ LK + E L +++ + ++ + +
Sbjct: 2172 VILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKL 2231
Query: 188 LYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKP-PEKPPERGGDEKQMA 246
L S +L +E + Q+EI + +T +L N LK E GD++ M
Sbjct: 2232 LSSF-----KSLLEE----KEQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQEIMK 2282
Query: 247 LLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGG---ELDR 303
Q + E L++ IE+L+A + E+ L ++L+E H L G L+R
Sbjct: 2283 ATEQSLDPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVENLER 2342
Query: 304 TRDEASRALQRAHEQTETVRKCLQTTVAELE---RQLAASRAQVSTAEKEREELKNRLHW 360
+ A + A + E + ++T A++E + L V T E+E L N L
Sbjct: 2343 ELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQK 2402
Query: 361 QMKRLTE 367
+ +R++E
Sbjct: 2403 EQERISE 2409
Score = 48.0 bits (109), Expect = 6e-05
Identities = 66/373 (17%), Positives = 158/373 (42%), Gaps = 29/373 (7%)
Query: 22 ETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKE 81
+ +N REL+M E SK + + + + + + ++ LR+ +
Sbjct: 2154 KVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKEN 2213
Query: 82 QNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAP 141
Q+Q+ + + + +L+ + +I E+ ++ ++ + +E + +A
Sbjct: 2214 LTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVAA 2273
Query: 142 I---PDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLY-SLYLVTTM 197
+ +++KAT+ L + + ++ E+L L +K + + + L S + +
Sbjct: 2274 LCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLL 2333
Query: 198 TLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAE 257
E+L + + EI R N++ H +L E + ++ L +I + +
Sbjct: 2334 KGRVENL--ERELEIARTNQE-------HAAL-------EAENSKGEVETLKAKIEGMTQ 2377
Query: 258 NNISLKSEIERLKASVIRTEESALANE-KRLQEKMHECAQLGGELDRTRDEASRALQRAH 316
+ L+ ++ IR+E+ L NE ++ QE++ E + + E + +
Sbjct: 2378 SLRGLELDVV-----TIRSEKENLTNELQKEQERISELEIINSSFENILQEKEQEKVQMK 2432
Query: 317 EQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNR---LHWQMKRLTENFEQAQ 373
E++ T + LQT + EL ++AA + + + L ++ L + +L + ++A+
Sbjct: 2433 EKSSTAMEMLQTQLKELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEAK 2492
Query: 374 LRILGLQTQVQSL 386
+ LQ+ V L
Sbjct: 2493 NNYIVLQSSVNGL 2505
Score = 46.0 bits (104), Expect = 2e-04
Identities = 70/324 (21%), Positives = 140/324 (43%), Gaps = 29/324 (8%)
Query: 24 QNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQN 83
Q+ L L+ ++ L + K +F ++VN K+ E + E+ E+ E
Sbjct: 2579 QDTLEVLQSSYKNLENELELTKMDK-MSFVEKVNKMTAKET--ELQREMHEMAQKTAELQ 2635
Query: 84 DQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIP 143
++L + + QL+ E+ + T + ++ + + ++++++ +
Sbjct: 2636 EELSGEKNRLAGELQLLLEEIKSSKDQLKELTLENSELKKSLDCMH---KDQVEKEGKVR 2692
Query: 144 DLLKATQMRLKDAQQA-QAIAEHNAEQLARELNCAREKVVHIFRYLYSLYL-VTTMTLTQ 201
+ + Q+RL +A++ QA+ +Q E+ REK+ L S L + + ++
Sbjct: 2693 EEIAEYQLRLHEAEKKHQALLLDTNKQYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSK 2752
Query: 202 EDLFG------QSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQL 255
E+L Q E+ + D +V N LK K ER + +M LL + QL
Sbjct: 2753 EELNNSLKATTQILEELKKTKMDNLKYV---NQLK---KENERA--QGKMKLLIKSCKQL 2804
Query: 256 AENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQR- 314
E L+ E+ +L+A+ + + + + K + E E +L L+ EA L +
Sbjct: 2805 EEEKEILQKELSQLQAAQEKQKTGTVMDTK-VDELTTEIKELKETLEEKTKEADEYLDKY 2863
Query: 315 -----AHEQTETVRKCLQTTVAEL 333
+HE+ E ++ L+T VA L
Sbjct: 2864 CSLLISHEKLEKAKEMLETQVAHL 2887
Score = 44.4 bits (100), Expect = 7e-04
Identities = 72/334 (21%), Positives = 143/334 (42%), Gaps = 26/334 (7%)
Query: 72 IDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLK 131
+D+L MKE+ +L+ ++ + L Q+ E + ++ +S ++ E+ + K
Sbjct: 1976 LDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQT---LSSDVS-ELLKDKTH 2031
Query: 132 FQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSL 191
QEKLQ L L T+ L++ Q AQ E E L +E + ++ ++
Sbjct: 2032 LQEKLQSLEKDSQALSLTKCELEN-QIAQLNKE--KELLVKESESLQARLSESDYEKLNV 2088
Query: 192 YLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPER-GGDEKQMALLNQ 250
L ++ F S + + VH L EK R DEK+ + +
Sbjct: 2089 SKALEAALVEKGEFALRLS-----STQEEVHQLRRGI----EKLRVRIEADEKKQLHIAE 2139
Query: 251 RISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASR 310
++ + N SLK ++E L+ + +EE+ E + + + A++ L +E +R
Sbjct: 2140 KLKERERENDSLKDKVENLERELQMSEEN---QELVILDAENSKAEV-ETLKTQIEEMAR 2195
Query: 311 ALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFE 370
+L+ T+R + L +Q+ + Q+S +K K+ L + + + E
Sbjct: 2196 SLKVFELDLVTLR----SEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKE 2251
Query: 371 QAQLRILGLQTQVQSLRRTASSTGDGDGENQECT 404
+++ + LQ Q++ L ++ GD E + T
Sbjct: 2252 ESKTAVEMLQNQLKELNEAVAAL-CGDQEIMKAT 2284
Score = 43.2 bits (97), Expect = 0.002
Identities = 65/330 (19%), Positives = 147/330 (44%), Gaps = 39/330 (11%)
Query: 17 RCQHRETQNKLRELEMKFEG----LATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEI 72
+ Q++E +NK+ ELE++ +G + N + Q + +V + ++ + R+E+
Sbjct: 284 KAQNQELRNKINELELRLQGHEKEMKGQVNKFQELQLQLEKAKVELIEKEKVLNKCRDEL 343
Query: 73 ------------------DELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXN 114
+L+ L ++ + Q Q+ +Q ++E+ ++
Sbjct: 344 VRTTAQYDQASTKYTALEQKLKKLTEDLSCQRQNAESARCSLEQKIKEKEKEFQEELSRQ 403
Query: 115 TRISEQINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLAREL 174
R + ++ E ++K + ++LQ+ + ++L+A +L +Q E+N E+ ++L
Sbjct: 404 QRSFQTLDQECIQMKARLTQELQQAKNMHNVLQAELDKLTSVKQQ---LENNLEEFKQKL 460
Query: 175 NCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGN------KDQTVHVLLHNS 228
C E+ + + + + +E+ +S SE + + + L+ S
Sbjct: 461 -CRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNIKQCLNQS 519
Query: 229 LKPPEKPPERGGDEKQMAL-LNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRL 287
E+ + ++ M L ++I+Q EN+++L E+LK +V E+ ++ L
Sbjct: 520 QNFAEEMKAKNTSQETMLRDLQEKINQ-QENSLTL----EKLKLAVADLEKQRDCSQDLL 574
Query: 288 QEKMHECAQLGGELDRTRDEASRALQRAHE 317
+++ H QL +L +T E S+AL A E
Sbjct: 575 KKREHHIEQLNDKLSKTEKE-SKALLSALE 603
Score = 39.1 bits (87), Expect = 0.028
Identities = 70/355 (19%), Positives = 147/355 (41%), Gaps = 23/355 (6%)
Query: 61 LKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQ 120
LK +E R +I+EL ++ +++ K+ + Q +E+ + + + ++
Sbjct: 283 LKAQNQELRNKINELELRLQGHEKEMKGQVNKFQELQLQLEKAKVELIEKEKVLNKCRDE 342
Query: 121 I---NLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCA 177
+ + + K+ Q+L + + L + ++A+ A+ E ++ +E
Sbjct: 343 LVRTTAQYDQASTKYTALEQKLKKLTEDLSCQR---QNAESARCSLEQKIKEKEKEFQEE 399
Query: 178 REKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVL--LHNSLKPPEKP 235
+ F+ L + LTQE ++ + + D+ V L N+L+ ++
Sbjct: 400 LSRQQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQK 459
Query: 236 PERGGDEKQMALLNQR-----ISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEK 290
R Q + + + + ++ + N LKS E+ KA + E+ L N K+ +
Sbjct: 460 LCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQ-KAREVCHLEAELKNIKQCLNQ 518
Query: 291 MHECAQLGGELDRTRDEASRALQRAHEQTE---TVRKCLQTTVAELERQLAASRAQVSTA 347
A+ + +++ R LQ Q E T+ K L+ VA+LE+Q S+ +
Sbjct: 519 SQNFAEEMKAKNTSQETMLRDLQEKINQQENSLTLEK-LKLAVADLEKQRDCSQDLLKKR 577
Query: 348 EKEREELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRRTASSTGDGDGENQE 402
E E+L ++L TE +A L L L+ + L+ + EN++
Sbjct: 578 EHHIEQLNDKL-----SKTEKESKALLSALELKKKEYELKEEKTLFSCWKSENEK 627
Score = 33.9 bits (74), Expect = 1.1
Identities = 56/308 (18%), Positives = 126/308 (40%), Gaps = 24/308 (7%)
Query: 81 EQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQEL- 139
+Q + +D + L+ Q +EQ ++ ++ NLE++ + ++ ++K+Q L
Sbjct: 2513 KQKLEKKDEEISRLKNQIQDQEQLVSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQ 2572
Query: 140 ---APIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTT 196
A + D L+ Q K+ + + + + ++N K + R ++ + T
Sbjct: 2573 SKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTA 2632
Query: 197 MTLTQEDLFGQSQSEIG---------RGNKDQTVHVLLHNS-LKPPEKPPERGGDEKQMA 246
QE+L G+ G + +KDQ + L NS LK + EK+
Sbjct: 2633 E--LQEELSGEKNRLAGELQLLLEEIKSSKDQLKELTLENSELKKSLDCMHKDQVEKE-- 2688
Query: 247 LLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRD 306
+ ++AE + L ++ +A ++ T + + +EK+ + L +
Sbjct: 2689 --GKVREEIAEYQLRLHEAEKKHQALLLDTNKQYEVEIQTYREKLTSKEEC---LSSQKL 2743
Query: 307 EASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLT 366
E L+ + E+ K + EL++ + V+ +KE E + ++ +K
Sbjct: 2744 EID-LLKSSKEELNNSLKATTQILEELKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCK 2802
Query: 367 ENFEQAQL 374
+ E+ ++
Sbjct: 2803 QLEEEKEI 2810
Score = 32.7 bits (71), Expect = 2.4
Identities = 37/159 (23%), Positives = 63/159 (39%), Gaps = 14/159 (8%)
Query: 240 GDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGG 299
G+ M+ + QL+E E+E ++ + + A A K E + +
Sbjct: 1964 GELDTMSKKTTALDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQTLSSDVS 2023
Query: 300 ELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRL- 358
EL + + LQ + ++ L T ELE Q+A + KE E L+ RL
Sbjct: 2024 ELLKDKTHLQEKLQSLEKDSQA----LSLTKCELENQIAQLNKEKELLVKESESLQARLS 2079
Query: 359 --HWQMKRLTENFEQA-------QLRILGLQTQVQSLRR 388
++ +++ E A LR+ Q +V LRR
Sbjct: 2080 ESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRR 2118
>CR456526-1|CAG30412.1| 1960|Homo sapiens MYH9 protein.
Length = 1960
Score = 54.8 bits (126), Expect = 5e-07
Identities = 72/390 (18%), Positives = 172/390 (44%), Gaps = 29/390 (7%)
Query: 22 ETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKE 81
E + ELE + T LM SK+ + +V L++ R ++++E++T ++E
Sbjct: 1487 EAMEQKAELERLNKQFRTEMEDLMSSKDDVGK---SVHELEKSKRALEQQVEEMKTQLEE 1543
Query: 82 QNDQLQ---DYRVKY-LQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQ 137
D+LQ D +++ + Q + + R + +Q+ +++ ++ + +++ +
Sbjct: 1544 LEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERK 1603
Query: 138 ELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTM 197
+ + K +M LKD + A N ++ ++L + ++ R L
Sbjct: 1604 QRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMREL------DDT 1657
Query: 198 TLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAE 257
++E++ Q++ + + + L L E+ +R +++ L ++ + +
Sbjct: 1658 RASREEILAQAKENEKKLKSMEAEMIQLQEELAAAER-AKRQAQQERDELADEIANSSGK 1716
Query: 258 NNISLKSEIERLKASVIRTEE--------SALANEKRLQEKMHECAQLGGELDRTRDEAS 309
++L+ E RL+A + + EE + L N+ RL++ + Q+ +L+ R A
Sbjct: 1717 GALALE-EKRRLEARIAQLEEELEEEQGNTELIND-RLKKANLQIDQINTDLNLERSHAQ 1774
Query: 310 RALQRAHEQTETVRKCLQTTVAELERQLAAS-RAQVSTAEKEREELKNRLHWQMKR---L 365
+ + A +Q E K L+ + E+E + + +A ++ E + +L+ +L + K
Sbjct: 1775 KN-ENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAA 1833
Query: 366 TENFEQAQLRILGLQTQVQSLRRTASSTGD 395
+ + + ++ + QV RR A D
Sbjct: 1834 CKQVRRTEKKLKDVLLQVDDERRNAEQYKD 1863
Score = 50.4 bits (115), Expect = 1e-05
Identities = 81/367 (22%), Positives = 155/367 (42%), Gaps = 50/367 (13%)
Query: 26 KLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQ 85
K+RE ++ E T L + Q +++ ++ Q E E +ELR + + +
Sbjct: 856 KVREKQLAAENRLTEMETL---QSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQE 912
Query: 86 LQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDL 145
L++ L+A+ EE+R Q Q N++ +L+ +E ++ + +
Sbjct: 913 LEEI-CHDLEARVEEEEERCQHLQAEKKKM----QQNIQELEEQLEEEESARQKLQLEKV 967
Query: 146 LKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLF 205
T+ +LK ++ Q I E +LA+E +++ T LT+E+
Sbjct: 968 --TTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEF-----------TTNLTEEEEK 1014
Query: 206 GQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSE 265
+S +++ NK + + L L+ EK +R EK L + L++ L+++
Sbjct: 1015 SKSLAKLK--NKHEAMITDLEERLRREEK--QRQELEKTRRKLEGDSTDLSDQIAELQAQ 1070
Query: 266 IERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKC 325
I LK + + EE A R++E E AQ L + R+
Sbjct: 1071 IAELKMQLAKKEEELQAALARVEE---EAAQKNMALKKIRE------------------- 1108
Query: 326 LQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQ--AQLRILGLQTQ- 382
L++ ++EL+ L + RA + AEK++ +L L L + + AQ + + Q
Sbjct: 1109 LESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQE 1168
Query: 383 VQSLRRT 389
V L++T
Sbjct: 1169 VNILKKT 1175
Score = 39.9 bits (89), Expect = 0.016
Identities = 83/392 (21%), Positives = 162/392 (41%), Gaps = 24/392 (6%)
Query: 24 QNKLRELE-MKFEGLATHTNM---LMGSKEQAFEQEVNVRALKQCYREAREEI-DELRTL 78
+N+L E+E ++ + +A + L E E E +RA ++ EEI +L
Sbjct: 865 ENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAE-ELRARLTAKKQELEEICHDLEAR 923
Query: 79 MKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRIS-EQINLEIQRVKLKFQEKLQ 137
++E+ ++ Q + + + QQ ++E Q ++ E++ E + KL+ ++ +
Sbjct: 924 VEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIIL 983
Query: 138 E--LAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVT 195
E + K + R+ + E ++ LA+ N + + L
Sbjct: 984 EDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQR 1043
Query: 196 T-MTLTQEDLFGQSQ--SEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRI 252
+ T+ L G S S+ + Q + + + K E E++ A N +
Sbjct: 1044 QELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMAL 1103
Query: 253 SQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDE--ASR 310
++ E L+S+I L+ + S EK+ ++ E L EL+ T D A +
Sbjct: 1104 KKIRE----LESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQ 1159
Query: 311 ALQRAHEQ-TETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENF 369
L+ EQ ++K L+ E Q+ R + S A EEL +L Q KR+ N
Sbjct: 1160 ELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAV---EELAEQLE-QTKRVKANL 1215
Query: 370 EQAQLRILGLQTQVQSLRRTASSTGDGDGENQ 401
E+A+ + + ++ + + G GD E++
Sbjct: 1216 EKAKQTLENERGELANEVKVLLQ-GKGDSEHK 1246
Score = 39.9 bits (89), Expect = 0.016
Identities = 66/367 (17%), Positives = 149/367 (40%), Gaps = 28/367 (7%)
Query: 19 QHRETQNKLRELEMKF-EGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRT 77
+ ++ + +L+EL++KF EG T + ++ + +V + + ++ + +L
Sbjct: 1246 KRKKVEAQLQELQVKFNEGERVRTELA----DKVTKLQVELDNVTGLLSQSDSKSSKLTK 1301
Query: 78 LMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKL- 136
QLQD Q+L++E+ RQ ++ ++ N ++++ + + K
Sbjct: 1302 DFSALESQLQD-------TQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHN 1354
Query: 137 --QELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLV 194
+++A + + + +++D+ AE +L ++L ++ Y
Sbjct: 1355 LEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVA-AYDKLEK 1413
Query: 195 TTMTLTQE------DLFGQSQSEIGRGNKDQTVHVLLHN----SLKPPEKPPERGGDEKQ 244
T L QE DL Q QS K + LL S K E+ + ++
Sbjct: 1414 TKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEARE 1473
Query: 245 MALLNQRISQLAENNISLKSEIERLKASVIRTE-ESALANEKRLQEKMHECAQLGGELDR 303
+++ E + K+E+ERL RTE E ++++ + + +HE + L++
Sbjct: 1474 KETKALSLARALEEAMEQKAELERLNKQ-FRTEMEDLMSSKDDVGKSVHELEKSKRALEQ 1532
Query: 304 TRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMK 363
+E L+ ++ + L+ A + +++ EE K +L Q++
Sbjct: 1533 QVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVR 1592
Query: 364 RLTENFE 370
+ E
Sbjct: 1593 EMEAELE 1599
Score = 37.9 bits (84), Expect = 0.065
Identities = 69/336 (20%), Positives = 132/336 (39%), Gaps = 32/336 (9%)
Query: 28 RELEMKFEGLATHTNMLMGSKEQAFEQEVNVRA-LKQCYRE---AREEIDELRTLMKEQN 83
++LEM + L H + ++++A +Q ++A +K C RE R +E+ KE
Sbjct: 1613 KKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENE 1672
Query: 84 DQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIP 143
+L+ + +Q Q+ + R ++++I + L +EK
Sbjct: 1673 KKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEK-------- 1724
Query: 144 DLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQED 203
R +A+ AQ E EQ EL R K ++ + L + Q++
Sbjct: 1725 --------RRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKN 1776
Query: 204 LFGQSQSEIGRGNKDQTVHVL-LHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISL 262
+ Q E R NK+ V + + ++K K + L +I+QL E +
Sbjct: 1777 ENARQQLE--RQNKELKVKLQEMEGTVKSKYKA--------SITALEAKIAQLEEQLDNE 1826
Query: 263 KSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETV 322
E + V RTE+ ++ ++ Q + D+ + L+R E+ E
Sbjct: 1827 TKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQ-LKRQLEEAEEE 1885
Query: 323 RKCLQTTVAELERQLAASRAQVSTAEKEREELKNRL 358
+ + +L+R+L + +E LKN+L
Sbjct: 1886 AQRANASRRKLQRELEDATETADAMNREVSSLKNKL 1921
Score = 33.5 bits (73), Expect = 1.4
Identities = 76/359 (21%), Positives = 154/359 (42%), Gaps = 30/359 (8%)
Query: 48 KEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQX 107
+E+A E ++ ++Q + +A EE + EQ +Q + + +A+Q +E +R +
Sbjct: 1177 EEEAKTHEAQIQEMRQKHSQAVEE-------LAEQLEQTKRVKANLEKAKQTLENERGE- 1228
Query: 108 XXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNA 167
++ Q + + + K + +LQEL + + + L D + N
Sbjct: 1229 ---LANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNV 1285
Query: 168 EQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHN 227
L + + K+ F L S L T L QE +++ ++ K + V ++
Sbjct: 1286 TGLLSQSDSKSSKLTKDFSALES-QLQDTQELLQE----ENRQKLSLSTKLKQVEDEKNS 1340
Query: 228 SLKPPEKPPE-RGGDEKQMALLNQRISQL---AENNISLKSEIERLKASVIRTEES-ALA 282
+ E+ E + EKQ+A L+ +++ + E+++ E +K + + E +
Sbjct: 1341 FREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQR 1400
Query: 283 NEKRL--QEKMHEC-AQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAA 339
+E+++ +K+ + +L ELD + Q A E +K +AE E+ ++A
Sbjct: 1401 HEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSAC-NLEKKQKKFDQLLAE-EKTISA 1458
Query: 340 SRAQV-STAEKEREELKNRLHWQMKRLTENFEQ-AQLRILGLQ--TQVQSLRRTASSTG 394
A+ AE E E + + + L E EQ A+L L Q T+++ L + G
Sbjct: 1459 KYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVG 1517
>AL445666-1|CAH71810.1| 3114|Homo sapiens centromere protein F,
350/400ka (mitosin) protein.
Length = 3114
Score = 54.8 bits (126), Expect = 5e-07
Identities = 74/367 (20%), Positives = 154/367 (41%), Gaps = 30/367 (8%)
Query: 22 ETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNV-RALKQCYRE----------ARE 70
E +N++ +L + E L + L ++ +++NV +AL+ E +E
Sbjct: 2053 ELENQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQE 2112
Query: 71 EIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKL 130
E+ +LR +++ +++ K L + ++E+ R+ + ++ + + +L
Sbjct: 2113 EVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQEL 2172
Query: 131 KFQEKLQELAPIPDL---LKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRY 187
+ A + L ++ LK + E L +++ + ++ + +
Sbjct: 2173 VILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKL 2232
Query: 188 LYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKP-PEKPPERGGDEKQMA 246
L S +L +E + Q+EI + +T +L N LK E GD++ M
Sbjct: 2233 LSSF-----KSLLEE----KEQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQEIMK 2283
Query: 247 LLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGG---ELDR 303
Q + E L++ IE+L+A + E+ L ++L+E H L G L+R
Sbjct: 2284 ATEQSLDPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVENLER 2343
Query: 304 TRDEASRALQRAHEQTETVRKCLQTTVAELE---RQLAASRAQVSTAEKEREELKNRLHW 360
+ A + A + E + ++T A++E + L V T E+E L N L
Sbjct: 2344 ELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQK 2403
Query: 361 QMKRLTE 367
+ +R++E
Sbjct: 2404 EQERISE 2410
Score = 48.0 bits (109), Expect = 6e-05
Identities = 66/373 (17%), Positives = 158/373 (42%), Gaps = 29/373 (7%)
Query: 22 ETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKE 81
+ +N REL+M E SK + + + + + + ++ LR+ +
Sbjct: 2155 KVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKEN 2214
Query: 82 QNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAP 141
Q+Q+ + + + +L+ + +I E+ ++ ++ + +E + +A
Sbjct: 2215 LTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVAA 2274
Query: 142 I---PDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLY-SLYLVTTM 197
+ +++KAT+ L + + ++ E+L L +K + + + L S + +
Sbjct: 2275 LCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLL 2334
Query: 198 TLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAE 257
E+L + + EI R N++ H +L E + ++ L +I + +
Sbjct: 2335 KGRVENL--ERELEIARTNQE-------HAAL-------EAENSKGEVETLKAKIEGMTQ 2378
Query: 258 NNISLKSEIERLKASVIRTEESALANE-KRLQEKMHECAQLGGELDRTRDEASRALQRAH 316
+ L+ ++ IR+E+ L NE ++ QE++ E + + E + +
Sbjct: 2379 SLRGLELDVV-----TIRSEKENLTNELQKEQERISELEIINSSFENILQEKEQEKVQMK 2433
Query: 317 EQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNR---LHWQMKRLTENFEQAQ 373
E++ T + LQT + EL ++AA + + + L ++ L + +L + ++A+
Sbjct: 2434 EKSSTAMEMLQTQLKELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEAK 2493
Query: 374 LRILGLQTQVQSL 386
+ LQ+ V L
Sbjct: 2494 NNYIVLQSSVNGL 2506
Score = 46.0 bits (104), Expect = 2e-04
Identities = 70/324 (21%), Positives = 140/324 (43%), Gaps = 29/324 (8%)
Query: 24 QNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQN 83
Q+ L L+ ++ L + K +F ++VN K+ E + E+ E+ E
Sbjct: 2580 QDTLEVLQSSYKNLENELELTKMDK-MSFVEKVNKMTAKET--ELQREMHEMAQKTAELQ 2636
Query: 84 DQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIP 143
++L + + QL+ E+ + T + ++ + + ++++++ +
Sbjct: 2637 EELSGEKNRLAGELQLLLEEIKSSKDQLKELTLENSELKKSLDCMH---KDQVEKEGKVR 2693
Query: 144 DLLKATQMRLKDAQQA-QAIAEHNAEQLARELNCAREKVVHIFRYLYSLYL-VTTMTLTQ 201
+ + Q+RL +A++ QA+ +Q E+ REK+ L S L + + ++
Sbjct: 2694 EEIAEYQLRLHEAEKKHQALLLDTNKQYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSK 2753
Query: 202 EDLFG------QSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQL 255
E+L Q E+ + D +V N LK K ER + +M LL + QL
Sbjct: 2754 EELNNSLKATTQILEELKKTKMDNLKYV---NQLK---KENERA--QGKMKLLIKSCKQL 2805
Query: 256 AENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQR- 314
E L+ E+ +L+A+ + + + + K + E E +L L+ EA L +
Sbjct: 2806 EEEKEILQKELSQLQAAQEKQKTGTVMDTK-VDELTTEIKELKETLEEKTKEADEYLDKY 2864
Query: 315 -----AHEQTETVRKCLQTTVAEL 333
+HE+ E ++ L+T VA L
Sbjct: 2865 CSLLISHEKLEKAKEMLETQVAHL 2888
Score = 44.4 bits (100), Expect = 7e-04
Identities = 72/334 (21%), Positives = 143/334 (42%), Gaps = 26/334 (7%)
Query: 72 IDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLK 131
+D+L MKE+ +L+ ++ + L Q+ E + ++ +S ++ E+ + K
Sbjct: 1977 LDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQT---LSSDVS-ELLKDKTH 2032
Query: 132 FQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSL 191
QEKLQ L L T+ L++ Q AQ E E L +E + ++ ++
Sbjct: 2033 LQEKLQSLEKDSQALSLTKCELEN-QIAQLNKE--KELLVKESESLQARLSESDYEKLNV 2089
Query: 192 YLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPER-GGDEKQMALLNQ 250
L ++ F S + + VH L EK R DEK+ + +
Sbjct: 2090 SKALEAALVEKGEFALRLS-----STQEEVHQLRRGI----EKLRVRIEADEKKQLHIAE 2140
Query: 251 RISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASR 310
++ + N SLK ++E L+ + +EE+ E + + + A++ L +E +R
Sbjct: 2141 KLKERERENDSLKDKVENLERELQMSEEN---QELVILDAENSKAEV-ETLKTQIEEMAR 2196
Query: 311 ALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFE 370
+L+ T+R + L +Q+ + Q+S +K K+ L + + + E
Sbjct: 2197 SLKVFELDLVTLR----SEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKE 2252
Query: 371 QAQLRILGLQTQVQSLRRTASSTGDGDGENQECT 404
+++ + LQ Q++ L ++ GD E + T
Sbjct: 2253 ESKTAVEMLQNQLKELNEAVAAL-CGDQEIMKAT 2285
Score = 37.9 bits (84), Expect = 0.065
Identities = 61/311 (19%), Positives = 131/311 (42%), Gaps = 18/311 (5%)
Query: 61 LKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQ 120
LK +E R +I+EL ++ +++ K+ + Q +E+ + + + ++
Sbjct: 283 LKAQNQELRNKINELELRLQGHEKEMKGQVNKFQELQLQLEKAKVELIEKEKVLNKCRDE 342
Query: 121 I---NLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCA 177
+ + + K+ Q+L + + L + ++A+ A+ E ++ +E
Sbjct: 343 LVRTTAQYDQASTKYTALEQKLKKLTEDLSCQR---QNAESARCSLEQKIKEKEKEFQEE 399
Query: 178 REKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVL--LHNSLKPPEKP 235
+ F+ L + LTQE ++ + + D+ V L N+L+ ++
Sbjct: 400 LSRQQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQK 459
Query: 236 PERGGDEKQMALLNQR-----ISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEK 290
R Q + + + + ++ + N LKS E+ KA + E+ L N K+ +
Sbjct: 460 LCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQ-KAREVCHLEAELKNIKQCLNQ 518
Query: 291 MHECAQLGGELDRTRDEASRALQRAHEQTE---TVRKCLQTTVAELERQLAASRAQVSTA 347
A+ + +++ R LQ Q E T+ K L+ VA+LE+Q S+ +
Sbjct: 519 SQNFAEEMKAKNTSQETMLRDLQEKINQQENSLTLEK-LKLAVADLEKQRDCSQDLLKKR 577
Query: 348 EKEREELKNRL 358
E E+L ++L
Sbjct: 578 EHHIEQLNDKL 588
Score = 37.5 bits (83), Expect = 0.086
Identities = 60/340 (17%), Positives = 129/340 (37%), Gaps = 11/340 (3%)
Query: 17 RCQHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELR 76
+ Q++E +NK+ ELE++ +G H + G + E ++ + K E + +++ R
Sbjct: 284 KAQNQELRNKINELELRLQG---HEKEMKGQVNKFQELQLQLEKAKVELIEKEKVLNKCR 340
Query: 77 TLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKL 136
+ Q KY +Q +++ + +I+ + +FQE+L
Sbjct: 341 DELVRTTAQYDQASTKYTALEQKLKKLTEDLSCQRQNAESARCSLEQKIKEKEKEFQEEL 400
Query: 137 QELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTT 196
L +++K A+ Q + + A+ + L +K+ + + L +
Sbjct: 401 SRQQRSFQTLDQECIQMK-ARLTQELQQ--AKNMHNVLQAELDKLTSVKQQLENNLEEFK 457
Query: 197 MTLTQ-EDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQL 255
L + E F SQ + + +N LK + R + L N +
Sbjct: 458 QKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNIKQCLN 517
Query: 256 AENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRA 315
N + + + + + + N++ + + +L++ RD + L++
Sbjct: 518 QSQNFAEEMKAKNTSQETMLRDLQEKINQQENSLTLEKLKLAVADLEKQRDCSQDLLKKR 577
Query: 316 HEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELK 355
E + L T E + L+A + +KE EELK
Sbjct: 578 EHHIEQLNDKLSKTEKESKALLSA----LELKKKEYEELK 613
Score = 33.9 bits (74), Expect = 1.1
Identities = 56/308 (18%), Positives = 126/308 (40%), Gaps = 24/308 (7%)
Query: 81 EQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQEL- 139
+Q + +D + L+ Q +EQ ++ ++ NLE++ + ++ ++K+Q L
Sbjct: 2514 KQKLEKKDEEISRLKNQIQDQEQLVSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQ 2573
Query: 140 ---APIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTT 196
A + D L+ Q K+ + + + + ++N K + R ++ + T
Sbjct: 2574 SKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTA 2633
Query: 197 MTLTQEDLFGQSQSEIG---------RGNKDQTVHVLLHNS-LKPPEKPPERGGDEKQMA 246
QE+L G+ G + +KDQ + L NS LK + EK+
Sbjct: 2634 E--LQEELSGEKNRLAGELQLLLEEIKSSKDQLKELTLENSELKKSLDCMHKDQVEKE-- 2689
Query: 247 LLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRD 306
+ ++AE + L ++ +A ++ T + + +EK+ + L +
Sbjct: 2690 --GKVREEIAEYQLRLHEAEKKHQALLLDTNKQYEVEIQTYREKLTSKEEC---LSSQKL 2744
Query: 307 EASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLT 366
E L+ + E+ K + EL++ + V+ +KE E + ++ +K
Sbjct: 2745 EID-LLKSSKEELNNSLKATTQILEELKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCK 2803
Query: 367 ENFEQAQL 374
+ E+ ++
Sbjct: 2804 QLEEEKEI 2811
Score = 32.7 bits (71), Expect = 2.4
Identities = 37/159 (23%), Positives = 63/159 (39%), Gaps = 14/159 (8%)
Query: 240 GDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGG 299
G+ M+ + QL+E E+E ++ + + A A K E + +
Sbjct: 1965 GELDTMSKKTTALDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQTLSSDVS 2024
Query: 300 ELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRL- 358
EL + + LQ + ++ L T ELE Q+A + KE E L+ RL
Sbjct: 2025 ELLKDKTHLQEKLQSLEKDSQA----LSLTKCELENQIAQLNKEKELLVKESESLQARLS 2080
Query: 359 --HWQMKRLTENFEQA-------QLRILGLQTQVQSLRR 388
++ +++ E A LR+ Q +V LRR
Sbjct: 2081 ESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRR 2119
>AL445305-6|CAH73032.1| 3114|Homo sapiens centromere protein F,
350/400ka (mitosin) protein.
Length = 3114
Score = 54.8 bits (126), Expect = 5e-07
Identities = 74/367 (20%), Positives = 154/367 (41%), Gaps = 30/367 (8%)
Query: 22 ETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNV-RALKQCYRE----------ARE 70
E +N++ +L + E L + L ++ +++NV +AL+ E +E
Sbjct: 2053 ELENQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQE 2112
Query: 71 EIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKL 130
E+ +LR +++ +++ K L + ++E+ R+ + ++ + + +L
Sbjct: 2113 EVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQEL 2172
Query: 131 KFQEKLQELAPIPDL---LKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRY 187
+ A + L ++ LK + E L +++ + ++ + +
Sbjct: 2173 VILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKL 2232
Query: 188 LYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKP-PEKPPERGGDEKQMA 246
L S +L +E + Q+EI + +T +L N LK E GD++ M
Sbjct: 2233 LSSF-----KSLLEE----KEQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQEIMK 2283
Query: 247 LLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGG---ELDR 303
Q + E L++ IE+L+A + E+ L ++L+E H L G L+R
Sbjct: 2284 ATEQSLDPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVENLER 2343
Query: 304 TRDEASRALQRAHEQTETVRKCLQTTVAELE---RQLAASRAQVSTAEKEREELKNRLHW 360
+ A + A + E + ++T A++E + L V T E+E L N L
Sbjct: 2344 ELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQK 2403
Query: 361 QMKRLTE 367
+ +R++E
Sbjct: 2404 EQERISE 2410
Score = 48.0 bits (109), Expect = 6e-05
Identities = 66/373 (17%), Positives = 158/373 (42%), Gaps = 29/373 (7%)
Query: 22 ETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKE 81
+ +N REL+M E SK + + + + + + ++ LR+ +
Sbjct: 2155 KVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKEN 2214
Query: 82 QNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAP 141
Q+Q+ + + + +L+ + +I E+ ++ ++ + +E + +A
Sbjct: 2215 LTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVAA 2274
Query: 142 I---PDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLY-SLYLVTTM 197
+ +++KAT+ L + + ++ E+L L +K + + + L S + +
Sbjct: 2275 LCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLL 2334
Query: 198 TLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAE 257
E+L + + EI R N++ H +L E + ++ L +I + +
Sbjct: 2335 KGRVENL--ERELEIARTNQE-------HAAL-------EAENSKGEVETLKAKIEGMTQ 2378
Query: 258 NNISLKSEIERLKASVIRTEESALANE-KRLQEKMHECAQLGGELDRTRDEASRALQRAH 316
+ L+ ++ IR+E+ L NE ++ QE++ E + + E + +
Sbjct: 2379 SLRGLELDVV-----TIRSEKENLTNELQKEQERISELEIINSSFENILQEKEQEKVQMK 2433
Query: 317 EQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNR---LHWQMKRLTENFEQAQ 373
E++ T + LQT + EL ++AA + + + L ++ L + +L + ++A+
Sbjct: 2434 EKSSTAMEMLQTQLKELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEAK 2493
Query: 374 LRILGLQTQVQSL 386
+ LQ+ V L
Sbjct: 2494 NNYIVLQSSVNGL 2506
Score = 46.0 bits (104), Expect = 2e-04
Identities = 70/324 (21%), Positives = 140/324 (43%), Gaps = 29/324 (8%)
Query: 24 QNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQN 83
Q+ L L+ ++ L + K +F ++VN K+ E + E+ E+ E
Sbjct: 2580 QDTLEVLQSSYKNLENELELTKMDK-MSFVEKVNKMTAKET--ELQREMHEMAQKTAELQ 2636
Query: 84 DQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIP 143
++L + + QL+ E+ + T + ++ + + ++++++ +
Sbjct: 2637 EELSGEKNRLAGELQLLLEEIKSSKDQLKELTLENSELKKSLDCMH---KDQVEKEGKVR 2693
Query: 144 DLLKATQMRLKDAQQA-QAIAEHNAEQLARELNCAREKVVHIFRYLYSLYL-VTTMTLTQ 201
+ + Q+RL +A++ QA+ +Q E+ REK+ L S L + + ++
Sbjct: 2694 EEIAEYQLRLHEAEKKHQALLLDTNKQYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSK 2753
Query: 202 EDLFG------QSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQL 255
E+L Q E+ + D +V N LK K ER + +M LL + QL
Sbjct: 2754 EELNNSLKATTQILEELKKTKMDNLKYV---NQLK---KENERA--QGKMKLLIKSCKQL 2805
Query: 256 AENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQR- 314
E L+ E+ +L+A+ + + + + K + E E +L L+ EA L +
Sbjct: 2806 EEEKEILQKELSQLQAAQEKQKTGTVMDTK-VDELTTEIKELKETLEEKTKEADEYLDKY 2864
Query: 315 -----AHEQTETVRKCLQTTVAEL 333
+HE+ E ++ L+T VA L
Sbjct: 2865 CSLLISHEKLEKAKEMLETQVAHL 2888
Score = 44.4 bits (100), Expect = 7e-04
Identities = 72/334 (21%), Positives = 143/334 (42%), Gaps = 26/334 (7%)
Query: 72 IDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLK 131
+D+L MKE+ +L+ ++ + L Q+ E + ++ +S ++ E+ + K
Sbjct: 1977 LDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQT---LSSDVS-ELLKDKTH 2032
Query: 132 FQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSL 191
QEKLQ L L T+ L++ Q AQ E E L +E + ++ ++
Sbjct: 2033 LQEKLQSLEKDSQALSLTKCELEN-QIAQLNKE--KELLVKESESLQARLSESDYEKLNV 2089
Query: 192 YLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPER-GGDEKQMALLNQ 250
L ++ F S + + VH L EK R DEK+ + +
Sbjct: 2090 SKALEAALVEKGEFALRLS-----STQEEVHQLRRGI----EKLRVRIEADEKKQLHIAE 2140
Query: 251 RISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASR 310
++ + N SLK ++E L+ + +EE+ E + + + A++ L +E +R
Sbjct: 2141 KLKERERENDSLKDKVENLERELQMSEEN---QELVILDAENSKAEV-ETLKTQIEEMAR 2196
Query: 311 ALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFE 370
+L+ T+R + L +Q+ + Q+S +K K+ L + + + E
Sbjct: 2197 SLKVFELDLVTLR----SEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKE 2252
Query: 371 QAQLRILGLQTQVQSLRRTASSTGDGDGENQECT 404
+++ + LQ Q++ L ++ GD E + T
Sbjct: 2253 ESKTAVEMLQNQLKELNEAVAAL-CGDQEIMKAT 2285
Score = 37.9 bits (84), Expect = 0.065
Identities = 61/311 (19%), Positives = 131/311 (42%), Gaps = 18/311 (5%)
Query: 61 LKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQ 120
LK +E R +I+EL ++ +++ K+ + Q +E+ + + + ++
Sbjct: 283 LKAQNQELRNKINELELRLQGHEKEMKGQVNKFQELQLQLEKAKVELIEKEKVLNKCRDE 342
Query: 121 I---NLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCA 177
+ + + K+ Q+L + + L + ++A+ A+ E ++ +E
Sbjct: 343 LVRTTAQYDQASTKYTALEQKLKKLTEDLSCQR---QNAESARCSLEQKIKEKEKEFQEE 399
Query: 178 REKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVL--LHNSLKPPEKP 235
+ F+ L + LTQE ++ + + D+ V L N+L+ ++
Sbjct: 400 LSRQQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQK 459
Query: 236 PERGGDEKQMALLNQR-----ISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEK 290
R Q + + + + ++ + N LKS E+ KA + E+ L N K+ +
Sbjct: 460 LCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQ-KAREVCHLEAELKNIKQCLNQ 518
Query: 291 MHECAQLGGELDRTRDEASRALQRAHEQTE---TVRKCLQTTVAELERQLAASRAQVSTA 347
A+ + +++ R LQ Q E T+ K L+ VA+LE+Q S+ +
Sbjct: 519 SQNFAEEMKAKNTSQETMLRDLQEKINQQENSLTLEK-LKLAVADLEKQRDCSQDLLKKR 577
Query: 348 EKEREELKNRL 358
E E+L ++L
Sbjct: 578 EHHIEQLNDKL 588
Score = 37.5 bits (83), Expect = 0.086
Identities = 60/340 (17%), Positives = 129/340 (37%), Gaps = 11/340 (3%)
Query: 17 RCQHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELR 76
+ Q++E +NK+ ELE++ +G H + G + E ++ + K E + +++ R
Sbjct: 284 KAQNQELRNKINELELRLQG---HEKEMKGQVNKFQELQLQLEKAKVELIEKEKVLNKCR 340
Query: 77 TLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKL 136
+ Q KY +Q +++ + +I+ + +FQE+L
Sbjct: 341 DELVRTTAQYDQASTKYTALEQKLKKLTEDLSCQRQNAESARCSLEQKIKEKEKEFQEEL 400
Query: 137 QELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTT 196
L +++K A+ Q + + A+ + L +K+ + + L +
Sbjct: 401 SRQQRSFQTLDQECIQMK-ARLTQELQQ--AKNMHNVLQAELDKLTSVKQQLENNLEEFK 457
Query: 197 MTLTQ-EDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQL 255
L + E F SQ + + +N LK + R + L N +
Sbjct: 458 QKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNIKQCLN 517
Query: 256 AENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRA 315
N + + + + + + N++ + + +L++ RD + L++
Sbjct: 518 QSQNFAEEMKAKNTSQETMLRDLQEKINQQENSLTLEKLKLAVADLEKQRDCSQDLLKKR 577
Query: 316 HEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELK 355
E + L T E + L+A + +KE EELK
Sbjct: 578 EHHIEQLNDKLSKTEKESKALLSA----LELKKKEYEELK 613
Score = 33.9 bits (74), Expect = 1.1
Identities = 56/308 (18%), Positives = 126/308 (40%), Gaps = 24/308 (7%)
Query: 81 EQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQEL- 139
+Q + +D + L+ Q +EQ ++ ++ NLE++ + ++ ++K+Q L
Sbjct: 2514 KQKLEKKDEEISRLKNQIQDQEQLVSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQ 2573
Query: 140 ---APIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTT 196
A + D L+ Q K+ + + + + ++N K + R ++ + T
Sbjct: 2574 SKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTA 2633
Query: 197 MTLTQEDLFGQSQSEIG---------RGNKDQTVHVLLHNS-LKPPEKPPERGGDEKQMA 246
QE+L G+ G + +KDQ + L NS LK + EK+
Sbjct: 2634 E--LQEELSGEKNRLAGELQLLLEEIKSSKDQLKELTLENSELKKSLDCMHKDQVEKE-- 2689
Query: 247 LLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRD 306
+ ++AE + L ++ +A ++ T + + +EK+ + L +
Sbjct: 2690 --GKVREEIAEYQLRLHEAEKKHQALLLDTNKQYEVEIQTYREKLTSKEEC---LSSQKL 2744
Query: 307 EASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLT 366
E L+ + E+ K + EL++ + V+ +KE E + ++ +K
Sbjct: 2745 EID-LLKSSKEELNNSLKATTQILEELKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCK 2803
Query: 367 ENFEQAQL 374
+ E+ ++
Sbjct: 2804 QLEEEKEI 2811
Score = 32.7 bits (71), Expect = 2.4
Identities = 37/159 (23%), Positives = 63/159 (39%), Gaps = 14/159 (8%)
Query: 240 GDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGG 299
G+ M+ + QL+E E+E ++ + + A A K E + +
Sbjct: 1965 GELDTMSKKTTALDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQTLSSDVS 2024
Query: 300 ELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRL- 358
EL + + LQ + ++ L T ELE Q+A + KE E L+ RL
Sbjct: 2025 ELLKDKTHLQEKLQSLEKDSQA----LSLTKCELENQIAQLNKEKELLVKESESLQARLS 2080
Query: 359 --HWQMKRLTENFEQA-------QLRILGLQTQVQSLRR 388
++ +++ E A LR+ Q +V LRR
Sbjct: 2081 ESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRR 2119
>AK131080-1|BAC85130.1| 563|Homo sapiens FLJ00279 protein protein.
Length = 563
Score = 54.8 bits (126), Expect = 5e-07
Identities = 72/390 (18%), Positives = 172/390 (44%), Gaps = 29/390 (7%)
Query: 22 ETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKE 81
E + ELE + T LM SK+ + +V L++ R ++++E++T ++E
Sbjct: 90 EAMEQKAELERLNKQFRTEMEDLMSSKDDVGK---SVHELEKSKRALEQQVEEMKTQLEE 146
Query: 82 QNDQLQ---DYRVKY-LQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQ 137
D+LQ D +++ + Q + + R + +Q+ +++ ++ + +++ +
Sbjct: 147 LEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERK 206
Query: 138 ELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTM 197
+ + K +M LKD + A N ++ ++L + ++ R L
Sbjct: 207 QRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMREL------DDT 260
Query: 198 TLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAE 257
++E++ Q++ + + + L L E+ +R +++ L ++ + +
Sbjct: 261 RASREEILAQAKENEKKLKSMEAEMIQLQEELAAAER-AKRQAQQERDELADEIANSSGK 319
Query: 258 NNISLKSEIERLKASVIRTEE--------SALANEKRLQEKMHECAQLGGELDRTRDEAS 309
++L+ E RL+A + + EE + L N+ RL++ + Q+ +L+ R A
Sbjct: 320 GALALE-EKRRLEARIAQLEEELEEEQGNTELIND-RLKKANLQIDQINTDLNLERSHAQ 377
Query: 310 RALQRAHEQTETVRKCLQTTVAELERQLAAS-RAQVSTAEKEREELKNRLHWQMKR---L 365
+ + A +Q E K L+ + E+E + + +A ++ E + +L+ +L + K
Sbjct: 378 KN-ENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAA 436
Query: 366 TENFEQAQLRILGLQTQVQSLRRTASSTGD 395
+ + + ++ + QV RR A D
Sbjct: 437 CKQVRRTEKKLKDVLLQVDDERRNAEQYKD 466
Score = 41.5 bits (93), Expect = 0.005
Identities = 46/177 (25%), Positives = 80/177 (45%), Gaps = 21/177 (11%)
Query: 235 PPERGGDEK-QMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHE 293
P E ++K ++ LN++ E+ +S K ++ + SV E+S A E++++E +
Sbjct: 87 PLEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGK---SVHELEKSKRALEQQVEEMKTQ 143
Query: 294 CAQLGGELDRTRD--------------EASRALQRAHEQTETVRKCLQTTVAELERQLAA 339
+L EL T D + R LQ EQ+E +K L V E+E +L
Sbjct: 144 LEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELED 203
Query: 340 SRAQVSTAEKEREELK---NRLHWQMKRLTENFEQAQLRILGLQTQVQSLRRTASST 393
R Q S A R++L+ L + +N ++A ++ LQ Q++ R T
Sbjct: 204 ERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDT 260
Score = 37.9 bits (84), Expect = 0.065
Identities = 69/336 (20%), Positives = 132/336 (39%), Gaps = 32/336 (9%)
Query: 28 RELEMKFEGLATHTNMLMGSKEQAFEQEVNVRA-LKQCYRE---AREEIDELRTLMKEQN 83
++LEM + L H + ++++A +Q ++A +K C RE R +E+ KE
Sbjct: 216 KKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENE 275
Query: 84 DQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIP 143
+L+ + +Q Q+ + R ++++I + L +EK
Sbjct: 276 KKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEK-------- 327
Query: 144 DLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQED 203
R +A+ AQ E EQ EL R K ++ + L + Q++
Sbjct: 328 --------RRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKN 379
Query: 204 LFGQSQSEIGRGNKDQTVHVL-LHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISL 262
+ Q E R NK+ V + + ++K K + L +I+QL E +
Sbjct: 380 ENARQQLE--RQNKELKVKLQEMEGTVKSKYKA--------SITALEAKIAQLEEQLDNE 429
Query: 263 KSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETV 322
E + V RTE+ ++ ++ Q + D+ + L+R E+ E
Sbjct: 430 TKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQ-LKRQLEEAEEE 488
Query: 323 RKCLQTTVAELERQLAASRAQVSTAEKEREELKNRL 358
+ + +L+R+L + +E LKN+L
Sbjct: 489 AQRANASRRKLQRELEDATETADAMNREVSSLKNKL 524
>AB191263-1|BAD52439.1| 1960|Homo sapiens non-muscle myosin heavy
polypeptide 9 protein.
Length = 1960
Score = 54.8 bits (126), Expect = 5e-07
Identities = 72/390 (18%), Positives = 172/390 (44%), Gaps = 29/390 (7%)
Query: 22 ETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKE 81
E + ELE + T LM SK+ + +V L++ R ++++E++T ++E
Sbjct: 1487 EAMEQKAELERLNKQFRTEMEDLMSSKDDVGK---SVHELEKSKRALEQQVEEMKTQLEE 1543
Query: 82 QNDQLQ---DYRVKY-LQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQ 137
D+LQ D +++ + Q + + R + +Q+ +++ ++ + +++ +
Sbjct: 1544 LEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERK 1603
Query: 138 ELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTM 197
+ + K +M LKD + A N ++ ++L + ++ R L
Sbjct: 1604 QRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMREL------DDT 1657
Query: 198 TLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAE 257
++E++ Q++ + + + L L E+ +R +++ L ++ + +
Sbjct: 1658 RASREEILAQAKENEKKLKSMEAEMIQLQEELAAAER-AKRQAQQERDELADEIANSSGK 1716
Query: 258 NNISLKSEIERLKASVIRTEE--------SALANEKRLQEKMHECAQLGGELDRTRDEAS 309
++L+ E RL+A + + EE + L N+ RL++ + Q+ +L+ R A
Sbjct: 1717 GALALE-EKRRLEARIAQLEEELEEEQGNTELIND-RLKKANLQIDQINTDLNLERSHAQ 1774
Query: 310 RALQRAHEQTETVRKCLQTTVAELERQLAAS-RAQVSTAEKEREELKNRLHWQMKR---L 365
+ + A +Q E K L+ + E+E + + +A ++ E + +L+ +L + K
Sbjct: 1775 KN-ENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAA 1833
Query: 366 TENFEQAQLRILGLQTQVQSLRRTASSTGD 395
+ + + ++ + QV RR A D
Sbjct: 1834 CKQVRRTEKKLKDVLLQVDDERRNAEQYKD 1863
Score = 50.4 bits (115), Expect = 1e-05
Identities = 81/367 (22%), Positives = 155/367 (42%), Gaps = 50/367 (13%)
Query: 26 KLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQ 85
K+RE ++ E T L + Q +++ ++ Q E E +ELR + + +
Sbjct: 856 KVREKQLAAENRLTEMETL---QSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQE 912
Query: 86 LQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDL 145
L++ L+A+ EE+R Q Q N++ +L+ +E ++ + +
Sbjct: 913 LEEI-CHDLEARVEEEEERCQHLQAEKKKM----QQNIQELEEQLEEEESARQKLQLEKV 967
Query: 146 LKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLF 205
T+ +LK ++ Q I E +LA+E +++ T LT+E+
Sbjct: 968 --TTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEF-----------TTNLTEEEEK 1014
Query: 206 GQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSE 265
+S +++ NK + + L L+ EK +R EK L + L++ L+++
Sbjct: 1015 SKSLAKLK--NKHEAMITDLEERLRREEK--QRQELEKTRRKLEGDSTDLSDQIAELQAQ 1070
Query: 266 IERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKC 325
I LK + + EE A R++E E AQ L + R+
Sbjct: 1071 IAELKMQLAKKEEELQAALARVEE---EAAQKNMALKKIRE------------------- 1108
Query: 326 LQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQ--AQLRILGLQTQ- 382
L++ ++EL+ L + RA + AEK++ +L L L + + AQ + + Q
Sbjct: 1109 LESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQE 1168
Query: 383 VQSLRRT 389
V L++T
Sbjct: 1169 VNILKKT 1175
Score = 39.9 bits (89), Expect = 0.016
Identities = 83/392 (21%), Positives = 162/392 (41%), Gaps = 24/392 (6%)
Query: 24 QNKLRELE-MKFEGLATHTNM---LMGSKEQAFEQEVNVRALKQCYREAREEI-DELRTL 78
+N+L E+E ++ + +A + L E E E +RA ++ EEI +L
Sbjct: 865 ENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAE-ELRARLTAKKQELEEICHDLEAR 923
Query: 79 MKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRIS-EQINLEIQRVKLKFQEKLQ 137
++E+ ++ Q + + + QQ ++E Q ++ E++ E + KL+ ++ +
Sbjct: 924 VEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIIL 983
Query: 138 E--LAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVT 195
E + K + R+ + E ++ LA+ N + + L
Sbjct: 984 EDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQR 1043
Query: 196 T-MTLTQEDLFGQSQ--SEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRI 252
+ T+ L G S S+ + Q + + + K E E++ A N +
Sbjct: 1044 QELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMAL 1103
Query: 253 SQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDE--ASR 310
++ E L+S+I L+ + S EK+ ++ E L EL+ T D A +
Sbjct: 1104 KKIRE----LESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQ 1159
Query: 311 ALQRAHEQ-TETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENF 369
L+ EQ ++K L+ E Q+ R + S A EEL +L Q KR+ N
Sbjct: 1160 ELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAV---EELAEQLE-QTKRVKANL 1215
Query: 370 EQAQLRILGLQTQVQSLRRTASSTGDGDGENQ 401
E+A+ + + ++ + + G GD E++
Sbjct: 1216 EKAKQTLENERGELANEVKVLLQ-GKGDSEHK 1246
Score = 39.9 bits (89), Expect = 0.016
Identities = 66/367 (17%), Positives = 149/367 (40%), Gaps = 28/367 (7%)
Query: 19 QHRETQNKLRELEMKF-EGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRT 77
+ ++ + +L+EL++KF EG T + ++ + +V + + ++ + +L
Sbjct: 1246 KRKKVEAQLQELQVKFNEGERVRTELA----DKVTKLQVELDNVTGLLSQSDSKSSKLTK 1301
Query: 78 LMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKL- 136
QLQD Q+L++E+ RQ ++ ++ N ++++ + + K
Sbjct: 1302 DFSALESQLQD-------TQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHN 1354
Query: 137 --QELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLV 194
+++A + + + +++D+ AE +L ++L ++ Y
Sbjct: 1355 LEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVA-AYDKLEK 1413
Query: 195 TTMTLTQE------DLFGQSQSEIGRGNKDQTVHVLLHN----SLKPPEKPPERGGDEKQ 244
T L QE DL Q QS K + LL S K E+ + ++
Sbjct: 1414 TKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEARE 1473
Query: 245 MALLNQRISQLAENNISLKSEIERLKASVIRTE-ESALANEKRLQEKMHECAQLGGELDR 303
+++ E + K+E+ERL RTE E ++++ + + +HE + L++
Sbjct: 1474 KETKALSLARALEEAMEQKAELERLNKQ-FRTEMEDLMSSKDDVGKSVHELEKSKRALEQ 1532
Query: 304 TRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMK 363
+E L+ ++ + L+ A + +++ EE K +L Q++
Sbjct: 1533 QVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVR 1592
Query: 364 RLTENFE 370
+ E
Sbjct: 1593 EMEAELE 1599
Score = 37.9 bits (84), Expect = 0.065
Identities = 69/336 (20%), Positives = 132/336 (39%), Gaps = 32/336 (9%)
Query: 28 RELEMKFEGLATHTNMLMGSKEQAFEQEVNVRA-LKQCYRE---AREEIDELRTLMKEQN 83
++LEM + L H + ++++A +Q ++A +K C RE R +E+ KE
Sbjct: 1613 KKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENE 1672
Query: 84 DQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIP 143
+L+ + +Q Q+ + R ++++I + L +EK
Sbjct: 1673 KKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEK-------- 1724
Query: 144 DLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQED 203
R +A+ AQ E EQ EL R K ++ + L + Q++
Sbjct: 1725 --------RRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKN 1776
Query: 204 LFGQSQSEIGRGNKDQTVHVL-LHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISL 262
+ Q E R NK+ V + + ++K K + L +I+QL E +
Sbjct: 1777 ENARQQLE--RQNKELKVKLQEMEGTVKSKYKA--------SITALEAKIAQLEEQLDNE 1826
Query: 263 KSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETV 322
E + V RTE+ ++ ++ Q + D+ + L+R E+ E
Sbjct: 1827 TKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQ-LKRQLEEAEEE 1885
Query: 323 RKCLQTTVAELERQLAASRAQVSTAEKEREELKNRL 358
+ + +L+R+L + +E LKN+L
Sbjct: 1886 AQRANASRRKLQRELEDATETADAMNREVSSLKNKL 1921
Score = 33.5 bits (73), Expect = 1.4
Identities = 76/359 (21%), Positives = 154/359 (42%), Gaps = 30/359 (8%)
Query: 48 KEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQX 107
+E+A E ++ ++Q + +A EE + EQ +Q + + +A+Q +E +R +
Sbjct: 1177 EEEAKTHEAQIQEMRQKHSQAVEE-------LAEQLEQTKRVKANLEKAKQTLENERGE- 1228
Query: 108 XXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNA 167
++ Q + + + K + +LQEL + + + L D + N
Sbjct: 1229 ---LANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNV 1285
Query: 168 EQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHN 227
L + + K+ F L S L T L QE +++ ++ K + V ++
Sbjct: 1286 TGLLSQSDSKSSKLTKDFSALES-QLQDTQELLQE----ENRQKLSLSTKLKQVEDEKNS 1340
Query: 228 SLKPPEKPPE-RGGDEKQMALLNQRISQL---AENNISLKSEIERLKASVIRTEES-ALA 282
+ E+ E + EKQ+A L+ +++ + E+++ E +K + + E +
Sbjct: 1341 FREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQR 1400
Query: 283 NEKRL--QEKMHEC-AQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAA 339
+E+++ +K+ + +L ELD + Q A E +K +AE E+ ++A
Sbjct: 1401 HEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSAC-NLEKKQKKFDQLLAE-EKTISA 1458
Query: 340 SRAQV-STAEKEREELKNRLHWQMKRLTENFEQ-AQLRILGLQ--TQVQSLRRTASSTG 394
A+ AE E E + + + L E EQ A+L L Q T+++ L + G
Sbjct: 1459 KYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVG 1517
>BC104906-1|AAI04907.1| 1938|Homo sapiens myosin, heavy chain 11,
smooth muscle protein.
Length = 1938
Score = 54.4 bits (125), Expect = 7e-07
Identities = 76/370 (20%), Positives = 154/370 (41%), Gaps = 36/370 (9%)
Query: 29 ELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQ- 87
ELE + L L+ SK+ + NV L++ R +++E++T ++E D+LQ
Sbjct: 1501 ELERTNKMLKAEMEDLVSSKDDVGK---NVHELEKSKRALETQMEEMKTQLEELEDELQA 1557
Query: 88 --DYRVKY-LQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPD 144
D +++ + Q L + R N Q+ ++ + + +++ ++ A
Sbjct: 1558 TEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAA 1617
Query: 145 LLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDL 204
K + LKD + A E+ ++L + ++ R L +++++
Sbjct: 1618 AKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDA------RASRDEI 1671
Query: 205 FGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKS 264
F ++ + + + L L E+ ++ EK+ L + S L+ N +L+
Sbjct: 1672 FATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKE-ELAEELASSLSGRN-ALQD 1729
Query: 265 EIERLKASVIRTEE-------SALANEKRLQEKMHECAQLGGELDRTR------DEASRA 311
E RL+A + + EE + A R+++ + QL EL R + A +
Sbjct: 1730 EKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQ 1789
Query: 312 LQRA--------HEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMK 363
L+R HE V+ ++T+A LE ++A QV +E++ L + K
Sbjct: 1790 LERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDK 1849
Query: 364 RLTENFEQAQ 373
+L E Q +
Sbjct: 1850 KLKEILLQVE 1859
Score = 45.6 bits (103), Expect = 3e-04
Identities = 72/380 (18%), Positives = 156/380 (41%), Gaps = 25/380 (6%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTL 78
+ ++ +N+L+ELE K L N+L + E ++ ++E++E+
Sbjct: 867 RQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHE 926
Query: 79 MKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQE 138
M+ + ++ +D + QQL E+++ ++ E+ E R KL+ ++ E
Sbjct: 927 MEARLEEEED------RGQQLQAERKKMAQQMLDLEEQLEEE---EAARQKLQLEKVTAE 977
Query: 139 --LAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYL---YSLYL 193
+ + D + + + + + E L L EK ++ + S+
Sbjct: 978 AKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMIS 1037
Query: 194 VTTMTLTQEDLFGQSQSEIGR---GNKDQTVHVLLHNSLKPPEKPPERGGDEKQM-ALLN 249
+ L +E+ Q ++ R G+ + + E + E+++ A L
Sbjct: 1038 ELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALA 1097
Query: 250 QRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMH-ECAQLGGELDRTRDEA 308
+ ++A+ N +LK +I L+ + +E L +E+ + K + LG EL+ + E
Sbjct: 1098 RLDDEIAQKNNALK-KIRELEGHISDLQED-LDSERAARNKAEKQKRDLGEELEALKTEL 1155
Query: 309 SRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTEN 368
L Q E +R + V L++ L + + E + +E++ + ++ LTE
Sbjct: 1156 EDTLDSTATQQE-LRAKREQEVTVLKKAL---DEETRSHEAQVQEMRQKHAQAVEELTEQ 1211
Query: 369 FEQAQLRILGLQTQVQSLRR 388
EQ + L Q+L +
Sbjct: 1212 LEQFKRAKANLDKNKQTLEK 1231
Score = 44.0 bits (99), Expect = 0.001
Identities = 78/398 (19%), Positives = 162/398 (40%), Gaps = 29/398 (7%)
Query: 22 ETQNKLRELEMKFEGLATHT----NMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRT 77
E + R LE + E + T + L +++ EVN++ALK + + DE
Sbjct: 1529 ELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQN- 1587
Query: 78 LMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQI-NLEIQRVK-LKFQEK 135
+E+ QLQ +Y + +E++R+Q ++ + +LE+Q +K +E+
Sbjct: 1588 --EEKRRQLQRQLHEY---ETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREE 1642
Query: 136 -LQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLV 194
+++L + +K Q L+DA+ ++ A++ ++ ++ + L +
Sbjct: 1643 AIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERA 1702
Query: 195 TTMT-LTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRIS 253
L +E+L + S + N Q L + E+ E ++ M ++ R+
Sbjct: 1703 RKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEE--EQGNMEAMSDRVR 1760
Query: 254 QLAENNISLKSEIERLKASVIRTEESALANE---KRLQEKMHEC-AQLGGELDRTRDEAS 309
+ + L +E+ +++ + E + E K L+ K+HE + + T
Sbjct: 1761 KATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALE 1820
Query: 310 RALQRAHEQTETVRKCLQTTVAEL---ERQLAASRAQVSTAEKEREELKNRLHW------ 360
+ + EQ E + Q L +++L QV K E+ K +
Sbjct: 1821 AKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVK 1880
Query: 361 QMKRLTENFEQAQLRILGLQTQVQSLRRTASSTGDGDG 398
Q+KR E E+ RI + ++Q A+ + + G
Sbjct: 1881 QLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMG 1918
Score = 42.3 bits (95), Expect = 0.003
Identities = 90/378 (23%), Positives = 154/378 (40%), Gaps = 46/378 (12%)
Query: 26 KLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQ 85
K+++LE + + N L SKE+ +E + L E E+ L L +
Sbjct: 979 KIKKLEDEILVMDDQNNKL--SKERKLLEE-RISDLTTNLAEEEEKAKNLTKLKNKHESM 1035
Query: 86 LQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQI-NLEIQRVKLKFQ-----EKLQE- 138
+ + V+ + ++ +E + + EQI +L+ Q +LK Q E+LQ
Sbjct: 1036 ISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAA 1095
Query: 139 LAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMT 198
LA + D + LK ++ + E L E AR K R L L T
Sbjct: 1096 LARLDDEIAQKNNALKKIRELEGHISDLQEDLDSE-RAARNKAEKQKRDLGE-ELEALKT 1153
Query: 199 LTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAEN 258
++ L + + R ++Q V VL K ++ E E Q+ + Q+ +Q E
Sbjct: 1154 ELEDTLDSTATQQELRAKREQEVTVLK----KALDE--ETRSHEAQVQEMRQKHAQAVEE 1207
Query: 259 NISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQ 318
+ +R KA+ L K+ EK E A L GEL R L +A ++
Sbjct: 1208 LTEQLEQFKRAKAN--------LDKNKQTLEK--ENADLAGEL--------RVLGQAKQE 1249
Query: 319 TETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHW---QMKRLTENFEQAQLR 375
E +K L+ V EL+ ++ S E+ R EL +++H +++ +T +A+ +
Sbjct: 1250 VEHKKKKLEAQVQELQ-------SKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGK 1302
Query: 376 ILGLQTQVQSLRRTASST 393
+ L V SL T
Sbjct: 1303 AIKLAKDVASLSSQLQDT 1320
Score = 38.3 bits (85), Expect = 0.049
Identities = 58/299 (19%), Positives = 130/299 (43%), Gaps = 23/299 (7%)
Query: 79 MKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQIN------LEIQRVKLKF 132
M+ + D+LQ + + +A+ ++E ++ + EQ+ E + ++++
Sbjct: 854 MQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRL 913
Query: 133 QEKLQELAPIPDLLKATQMRLKD-AQQAQAIAEHNAEQ-LARELNCAREKVVHIFRYLYS 190
K QEL I ++A +D QQ QA + A+Q L E E+ L
Sbjct: 914 AAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEK 973
Query: 191 LYLVTTMTLTQEDL--FGQSQSEIGRGNK--DQTVHVLLHNSLKPPEKPPERGG-DEKQM 245
+ + ++++ +++ + K ++ + L N + EK K
Sbjct: 974 VTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHE 1033
Query: 246 ALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTR 305
+++++ +L + S + E+E+LK + E A +++ + + A+L +L +
Sbjct: 1034 SMISELEVRLKKEEKS-RQELEKLKR---KLEGDASDFHEQIADLQAQIAELKMQLAKKE 1089
Query: 306 DEASRALQRAHEQ----TETVRKC--LQTTVAELERQLAASRAQVSTAEKEREELKNRL 358
+E AL R ++ ++K L+ +++L+ L + RA + AEK++ +L L
Sbjct: 1090 EELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEEL 1148
Score = 33.5 bits (73), Expect = 1.4
Identities = 28/137 (20%), Positives = 62/137 (45%), Gaps = 6/137 (4%)
Query: 242 EKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGEL 301
EK+ L+ +++ E + K E+ER + E ++++ + + +HE + L
Sbjct: 1480 EKETKALS--LARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRAL 1537
Query: 302 DRTRDEASRALQRAHEQ---TETVRKCLQTTVAELERQLAAS-RAQVSTAEKEREELKNR 357
+ +E L+ ++ TE + L+ + L+ Q +A+ E++R +L+ +
Sbjct: 1538 ETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQ 1597
Query: 358 LHWQMKRLTENFEQAQL 374
LH L + +Q L
Sbjct: 1598 LHEYETELEDERKQRAL 1614
Score = 32.7 bits (71), Expect = 2.4
Identities = 35/160 (21%), Positives = 67/160 (41%), Gaps = 4/160 (2%)
Query: 250 QRISQLAENNISLKS---EIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRD 306
+ I QL + +K E+E +AS +A NEK+ + + QL +L
Sbjct: 1642 EAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAER 1701
Query: 307 EASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLT 366
+A E E + L A L+ + A+++ E+E EE + + R+
Sbjct: 1702 ARKQADLEKEELAEELASSLSGRNA-LQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVR 1760
Query: 367 ENFEQAQLRILGLQTQVQSLRRTASSTGDGDGENQECTCK 406
+ +QA+ L T+ + ++ S+ + +N+E K
Sbjct: 1761 KATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSK 1800
>BC101677-1|AAI01678.1| 1938|Homo sapiens myosin, heavy chain 11,
smooth muscle protein.
Length = 1938
Score = 54.4 bits (125), Expect = 7e-07
Identities = 76/370 (20%), Positives = 154/370 (41%), Gaps = 36/370 (9%)
Query: 29 ELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQ- 87
ELE + L L+ SK+ + NV L++ R +++E++T ++E D+LQ
Sbjct: 1501 ELERTNKMLKAEMEDLVSSKDDVGK---NVHELEKSKRALETQMEEMKTQLEELEDELQA 1557
Query: 88 --DYRVKY-LQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPD 144
D +++ + Q L + R N Q+ ++ + + +++ ++ A
Sbjct: 1558 TEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAA 1617
Query: 145 LLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDL 204
K + LKD + A E+ ++L + ++ R L +++++
Sbjct: 1618 AKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDA------RASRDEI 1671
Query: 205 FGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKS 264
F ++ + + + L L E+ ++ EK+ L + S L+ N +L+
Sbjct: 1672 FATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKE-ELAEELASSLSGRN-ALQD 1729
Query: 265 EIERLKASVIRTEE-------SALANEKRLQEKMHECAQLGGELDRTR------DEASRA 311
E RL+A + + EE + A R+++ + QL EL R + A +
Sbjct: 1730 EKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQ 1789
Query: 312 LQRA--------HEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMK 363
L+R HE V+ ++T+A LE ++A QV +E++ L + K
Sbjct: 1790 LERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDK 1849
Query: 364 RLTENFEQAQ 373
+L E Q +
Sbjct: 1850 KLKEILLQVE 1859
Score = 45.6 bits (103), Expect = 3e-04
Identities = 72/380 (18%), Positives = 156/380 (41%), Gaps = 25/380 (6%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTL 78
+ ++ +N+L+ELE K L N+L + E ++ ++E++E+
Sbjct: 867 RQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHE 926
Query: 79 MKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQE 138
M+ + ++ +D + QQL E+++ ++ E+ E R KL+ ++ E
Sbjct: 927 MEARLEEEED------RGQQLQAERKKMAQQMLDLEEQLEEE---EAARQKLQLEKVTAE 977
Query: 139 --LAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYL---YSLYL 193
+ + D + + + + + E L L EK ++ + S+
Sbjct: 978 AKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMIS 1037
Query: 194 VTTMTLTQEDLFGQSQSEIGR---GNKDQTVHVLLHNSLKPPEKPPERGGDEKQM-ALLN 249
+ L +E+ Q ++ R G+ + + E + E+++ A L
Sbjct: 1038 ELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALA 1097
Query: 250 QRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMH-ECAQLGGELDRTRDEA 308
+ ++A+ N +LK +I L+ + +E L +E+ + K + LG EL+ + E
Sbjct: 1098 RLDDEIAQKNNALK-KIRELEGHISDLQED-LDSERAARNKAEKQKRDLGEELEALKTEL 1155
Query: 309 SRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTEN 368
L Q E +R + V L++ L + + E + +E++ + ++ LTE
Sbjct: 1156 EDTLDSTATQQE-LRAKREQEVTVLKKAL---DEETRSHEAQVQEMRQKHAQAVEELTEQ 1211
Query: 369 FEQAQLRILGLQTQVQSLRR 388
EQ + L Q+L +
Sbjct: 1212 LEQFKRAKANLDKNKQTLEK 1231
Score = 44.0 bits (99), Expect = 0.001
Identities = 78/398 (19%), Positives = 162/398 (40%), Gaps = 29/398 (7%)
Query: 22 ETQNKLRELEMKFEGLATHT----NMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRT 77
E + R LE + E + T + L +++ EVN++ALK + + DE
Sbjct: 1529 ELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQN- 1587
Query: 78 LMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQI-NLEIQRVK-LKFQEK 135
+E+ QLQ +Y + +E++R+Q ++ + +LE+Q +K +E+
Sbjct: 1588 --EEKRRQLQRQLHEY---ETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREE 1642
Query: 136 -LQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLV 194
+++L + +K Q L+DA+ ++ A++ ++ ++ + L +
Sbjct: 1643 AIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERA 1702
Query: 195 TTMT-LTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRIS 253
L +E+L + S + N Q L + E+ E ++ M ++ R+
Sbjct: 1703 RKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEE--EQGNMEAMSDRVR 1760
Query: 254 QLAENNISLKSEIERLKASVIRTEESALANE---KRLQEKMHEC-AQLGGELDRTRDEAS 309
+ + L +E+ +++ + E + E K L+ K+HE + + T
Sbjct: 1761 KATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALE 1820
Query: 310 RALQRAHEQTETVRKCLQTTVAEL---ERQLAASRAQVSTAEKEREELKNRLHW------ 360
+ + EQ E + Q L +++L QV K E+ K +
Sbjct: 1821 AKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVK 1880
Query: 361 QMKRLTENFEQAQLRILGLQTQVQSLRRTASSTGDGDG 398
Q+KR E E+ RI + ++Q A+ + + G
Sbjct: 1881 QLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMG 1918
Score = 42.3 bits (95), Expect = 0.003
Identities = 90/378 (23%), Positives = 154/378 (40%), Gaps = 46/378 (12%)
Query: 26 KLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQ 85
K+++LE + + N L SKE+ +E + L E E+ L L +
Sbjct: 979 KIKKLEDEILVMDDQNNKL--SKERKLLEE-RISDLTTNLAEEEEKAKNLTKLKNKHESM 1035
Query: 86 LQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQI-NLEIQRVKLKFQ-----EKLQE- 138
+ + V+ + ++ +E + + EQI +L+ Q +LK Q E+LQ
Sbjct: 1036 ISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAA 1095
Query: 139 LAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMT 198
LA + D + LK ++ + E L E AR K R L L T
Sbjct: 1096 LARLDDEIAQKNNALKKIRELEGHISDLQEDLDSE-RAARNKAEKQKRDLGE-ELEALKT 1153
Query: 199 LTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAEN 258
++ L + + R ++Q V VL K ++ E E Q+ + Q+ +Q E
Sbjct: 1154 ELEDTLDSTATQQELRAKREQEVTVLK----KALDE--ETRSHEAQVQEMRQKHAQAVEE 1207
Query: 259 NISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQ 318
+ +R KA+ L K+ EK E A L GEL R L +A ++
Sbjct: 1208 LTEQLEQFKRAKAN--------LDKNKQTLEK--ENADLAGEL--------RVLGQAKQE 1249
Query: 319 TETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHW---QMKRLTENFEQAQLR 375
E +K L+ V EL+ ++ S E+ R EL +++H +++ +T +A+ +
Sbjct: 1250 VEHKKKKLEAQVQELQ-------SKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGK 1302
Query: 376 ILGLQTQVQSLRRTASST 393
+ L V SL T
Sbjct: 1303 AIKLAKDVASLSSQLQDT 1320
Score = 38.3 bits (85), Expect = 0.049
Identities = 58/299 (19%), Positives = 130/299 (43%), Gaps = 23/299 (7%)
Query: 79 MKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQIN------LEIQRVKLKF 132
M+ + D+LQ + + +A+ ++E ++ + EQ+ E + ++++
Sbjct: 854 MQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRL 913
Query: 133 QEKLQELAPIPDLLKATQMRLKD-AQQAQAIAEHNAEQ-LARELNCAREKVVHIFRYLYS 190
K QEL I ++A +D QQ QA + A+Q L E E+ L
Sbjct: 914 AAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEK 973
Query: 191 LYLVTTMTLTQEDL--FGQSQSEIGRGNK--DQTVHVLLHNSLKPPEKPPERGG-DEKQM 245
+ + ++++ +++ + K ++ + L N + EK K
Sbjct: 974 VTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHE 1033
Query: 246 ALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTR 305
+++++ +L + S + E+E+LK + E A +++ + + A+L +L +
Sbjct: 1034 SMISELEVRLKKEEKS-RQELEKLKR---KLEGDASDFHEQIADLQAQIAELKMQLAKKE 1089
Query: 306 DEASRALQRAHEQ----TETVRKC--LQTTVAELERQLAASRAQVSTAEKEREELKNRL 358
+E AL R ++ ++K L+ +++L+ L + RA + AEK++ +L L
Sbjct: 1090 EELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEEL 1148
Score = 33.5 bits (73), Expect = 1.4
Identities = 28/137 (20%), Positives = 62/137 (45%), Gaps = 6/137 (4%)
Query: 242 EKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGEL 301
EK+ L+ +++ E + K E+ER + E ++++ + + +HE + L
Sbjct: 1480 EKETKALS--LARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRAL 1537
Query: 302 DRTRDEASRALQRAHEQ---TETVRKCLQTTVAELERQLAAS-RAQVSTAEKEREELKNR 357
+ +E L+ ++ TE + L+ + L+ Q +A+ E++R +L+ +
Sbjct: 1538 ETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQ 1597
Query: 358 LHWQMKRLTENFEQAQL 374
LH L + +Q L
Sbjct: 1598 LHEYETELEDERKQRAL 1614
Score = 32.7 bits (71), Expect = 2.4
Identities = 35/160 (21%), Positives = 67/160 (41%), Gaps = 4/160 (2%)
Query: 250 QRISQLAENNISLKS---EIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRD 306
+ I QL + +K E+E +AS +A NEK+ + + QL +L
Sbjct: 1642 EAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAER 1701
Query: 307 EASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLT 366
+A E E + L A L+ + A+++ E+E EE + + R+
Sbjct: 1702 ARKQADLEKEELAEELASSLSGRNA-LQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVR 1760
Query: 367 ENFEQAQLRILGLQTQVQSLRRTASSTGDGDGENQECTCK 406
+ +QA+ L T+ + ++ S+ + +N+E K
Sbjct: 1761 KATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSK 1800
>BC080545-1|AAH80545.1| 498|Homo sapiens MYH11 protein protein.
Length = 498
Score = 54.4 bits (125), Expect = 7e-07
Identities = 76/370 (20%), Positives = 154/370 (41%), Gaps = 36/370 (9%)
Query: 29 ELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQ- 87
ELE + L L+ SK+ + NV L++ R +++E++T ++E D+LQ
Sbjct: 27 ELERTNKMLKAEMEDLVSSKDDVGK---NVHELEKSKRALETQMEEMKTQLEELEDELQA 83
Query: 88 --DYRVKY-LQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPD 144
D +++ + Q L + R N Q+ ++ + + +++ ++ A
Sbjct: 84 TEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAA 143
Query: 145 LLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDL 204
K + LKD + A E+ ++L + ++ R L +++++
Sbjct: 144 AKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDA------RASRDEI 197
Query: 205 FGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKS 264
F ++ + + + L L E+ ++ EK+ L + S L+ N +L+
Sbjct: 198 FATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKE-ELAEELASSLSGRN-ALQD 255
Query: 265 EIERLKASVIRTEE-------SALANEKRLQEKMHECAQLGGELDRTR------DEASRA 311
E RL+A + + EE + A R+++ + QL EL R + A +
Sbjct: 256 EKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQ 315
Query: 312 LQRA--------HEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMK 363
L+R HE V+ ++T+A LE ++A QV +E++ L + K
Sbjct: 316 LERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDK 375
Query: 364 RLTENFEQAQ 373
+L E Q +
Sbjct: 376 KLKEILLQVE 385
Score = 44.0 bits (99), Expect = 0.001
Identities = 78/398 (19%), Positives = 162/398 (40%), Gaps = 29/398 (7%)
Query: 22 ETQNKLRELEMKFEGLATHT----NMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRT 77
E + R LE + E + T + L +++ EVN++ALK + + DE
Sbjct: 55 ELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQN- 113
Query: 78 LMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQI-NLEIQRVK-LKFQEK 135
+E+ QLQ +Y + +E++R+Q ++ + +LE+Q +K +E+
Sbjct: 114 --EEKRRQLQRQLHEY---ETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREE 168
Query: 136 -LQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLV 194
+++L + +K Q L+DA+ ++ A++ ++ ++ + L +
Sbjct: 169 AIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERA 228
Query: 195 TTMT-LTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRIS 253
L +E+L + S + N Q L + E+ E ++ M ++ R+
Sbjct: 229 RKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEE--EQGNMEAMSDRVR 286
Query: 254 QLAENNISLKSEIERLKASVIRTEESALANE---KRLQEKMHEC-AQLGGELDRTRDEAS 309
+ + L +E+ +++ + E + E K L+ K+HE + + T
Sbjct: 287 KATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALE 346
Query: 310 RALQRAHEQTETVRKCLQTTVAEL---ERQLAASRAQVSTAEKEREELKNRLHW------ 360
+ + EQ E + Q L +++L QV K E+ K +
Sbjct: 347 AKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVK 406
Query: 361 QMKRLTENFEQAQLRILGLQTQVQSLRRTASSTGDGDG 398
Q+KR E E+ RI + ++Q A+ + + G
Sbjct: 407 QLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMG 444
Score = 33.5 bits (73), Expect = 1.4
Identities = 28/137 (20%), Positives = 62/137 (45%), Gaps = 6/137 (4%)
Query: 242 EKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGEL 301
EK+ L+ +++ E + K E+ER + E ++++ + + +HE + L
Sbjct: 6 EKETKALS--LARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRAL 63
Query: 302 DRTRDEASRALQRAHEQ---TETVRKCLQTTVAELERQLAAS-RAQVSTAEKEREELKNR 357
+ +E L+ ++ TE + L+ + L+ Q +A+ E++R +L+ +
Sbjct: 64 ETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQ 123
Query: 358 LHWQMKRLTENFEQAQL 374
LH L + +Q L
Sbjct: 124 LHEYETELEDERKQRAL 140
Score = 32.7 bits (71), Expect = 2.4
Identities = 35/160 (21%), Positives = 67/160 (41%), Gaps = 4/160 (2%)
Query: 250 QRISQLAENNISLKS---EIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRD 306
+ I QL + +K E+E +AS +A NEK+ + + QL +L
Sbjct: 168 EAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAER 227
Query: 307 EASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLT 366
+A E E + L A L+ + A+++ E+E EE + + R+
Sbjct: 228 ARKQADLEKEELAEELASSLSGRNA-LQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVR 286
Query: 367 ENFEQAQLRILGLQTQVQSLRRTASSTGDGDGENQECTCK 406
+ +QA+ L T+ + ++ S+ + +N+E K
Sbjct: 287 KATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSK 326
>BC000280-1|AAH00280.1| 471|Homo sapiens MYH10 protein protein.
Length = 471
Score = 54.4 bits (125), Expect = 7e-07
Identities = 75/362 (20%), Positives = 157/362 (43%), Gaps = 27/362 (7%)
Query: 44 LMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQ---DYRVKYLQAQQLV 100
LM SK+ + NV L++ R ++++E+RT ++E D+LQ D +++ Q +
Sbjct: 11 LMSSKDDVGK---NVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAM 67
Query: 101 EEQ-RRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQA 159
+ Q R N + +++ ++ + +++ ++ A K ++ LKD +
Sbjct: 68 KAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQ 127
Query: 160 QAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQ 219
A +++ ++L + ++ R L +++++F QS+ + +
Sbjct: 128 IEAANKARDEVIKQLRKLQAQMKDYQREL------EEARASRDEIFAQSKESEKKLKSLE 181
Query: 220 TVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTE-- 277
+ L L E+ R E++ L I+ A +L E RL+A + + E
Sbjct: 182 AEILQLQEELASSER--ARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEE 239
Query: 278 -ESALANEKRLQEKMHECA----QLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAE 332
E +N + L ++ + L EL R A ++ A +Q E K L+ + E
Sbjct: 240 LEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKS-DNARQQLERQNKELKAKLQE 298
Query: 333 LERQLAAS-RAQVSTAEKEREELKNRLHWQMK-RLTEN--FEQAQLRILGLQTQVQSLRR 388
LE + + +A +S E + +L+ +L + K R N + + ++ + QV+ RR
Sbjct: 299 LEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERR 358
Query: 389 TA 390
A
Sbjct: 359 HA 360
Score = 34.3 bits (75), Expect = 0.80
Identities = 38/152 (25%), Positives = 69/152 (45%), Gaps = 17/152 (11%)
Query: 254 QLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRD------- 306
QL + L S + + +V E+S A E++++E + +L EL T D
Sbjct: 3 QLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEV 62
Query: 307 -------EASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQ--VSTAEKEREELKNR 357
+ R LQ EQ E ++ L V ELE +L R Q ++ A K++ E+ +
Sbjct: 63 NMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLK 122
Query: 358 -LHWQMKRLTENFEQAQLRILGLQTQVQSLRR 388
L Q++ + ++ ++ LQ Q++ +R
Sbjct: 123 DLEAQIEAANKARDEVIKQLRKLQAQMKDYQR 154
>AY520817-1|AAS98911.1| 1945|Homo sapiens smooth muscle myosin heavy
chain isoform SM2 protein.
Length = 1945
Score = 54.4 bits (125), Expect = 7e-07
Identities = 76/370 (20%), Positives = 154/370 (41%), Gaps = 36/370 (9%)
Query: 29 ELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQ- 87
ELE + L L+ SK+ + NV L++ R +++E++T ++E D+LQ
Sbjct: 1508 ELERTNKMLKAEMEDLVSSKDDVGK---NVHELEKSKRALETQMEEMKTQLEELEDELQA 1564
Query: 88 --DYRVKY-LQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPD 144
D +++ + Q L + R N Q+ ++ + + +++ ++ A
Sbjct: 1565 TEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAA 1624
Query: 145 LLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDL 204
K + LKD + A E+ ++L + ++ R L +++++
Sbjct: 1625 AKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDA------RASRDEI 1678
Query: 205 FGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKS 264
F ++ + + + L L E+ ++ EK+ L + S L+ N +L+
Sbjct: 1679 FATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKE-ELAEELASSLSGRN-ALQD 1736
Query: 265 EIERLKASVIRTEE-------SALANEKRLQEKMHECAQLGGELDRTR------DEASRA 311
E RL+A + + EE + A R+++ + QL EL R + A +
Sbjct: 1737 EKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQ 1796
Query: 312 LQRA--------HEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMK 363
L+R HE V+ ++T+A LE ++A QV +E++ L + K
Sbjct: 1797 LERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDK 1856
Query: 364 RLTENFEQAQ 373
+L E Q +
Sbjct: 1857 KLKEILLQVE 1866
Score = 45.6 bits (103), Expect = 3e-04
Identities = 72/380 (18%), Positives = 156/380 (41%), Gaps = 25/380 (6%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTL 78
+ ++ +N+L+ELE K L N+L + E ++ ++E++E+
Sbjct: 874 RQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHE 933
Query: 79 MKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQE 138
M+ + ++ +D + QQL E+++ ++ E+ E R KL+ ++ E
Sbjct: 934 MEARLEEEED------RGQQLQAERKKMAQQMLDLEEQLEEE---EAARQKLQLEKVTAE 984
Query: 139 --LAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYL---YSLYL 193
+ + D + + + + + E L L EK ++ + S+
Sbjct: 985 AKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMIS 1044
Query: 194 VTTMTLTQEDLFGQSQSEIGR---GNKDQTVHVLLHNSLKPPEKPPERGGDEKQM-ALLN 249
+ L +E+ Q ++ R G+ + + E + E+++ A L
Sbjct: 1045 ELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALA 1104
Query: 250 QRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMH-ECAQLGGELDRTRDEA 308
+ ++A+ N +LK +I L+ + +E L +E+ + K + LG EL+ + E
Sbjct: 1105 RLDDEIAQKNNALK-KIRELEGHISDLQED-LDSERAARNKAEKQKRDLGEELEALKTEL 1162
Query: 309 SRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTEN 368
L Q E +R + V L++ L + + E + +E++ + ++ LTE
Sbjct: 1163 EDTLDSTATQQE-LRAKREQEVTVLKKAL---DEETRSHEAQVQEMRQKHAQAVEELTEQ 1218
Query: 369 FEQAQLRILGLQTQVQSLRR 388
EQ + L Q+L +
Sbjct: 1219 LEQFKRAKANLDKNKQTLEK 1238
Score = 44.0 bits (99), Expect = 0.001
Identities = 78/398 (19%), Positives = 162/398 (40%), Gaps = 29/398 (7%)
Query: 22 ETQNKLRELEMKFEGLATHT----NMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRT 77
E + R LE + E + T + L +++ EVN++ALK + + DE
Sbjct: 1536 ELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQN- 1594
Query: 78 LMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQI-NLEIQRVK-LKFQEK 135
+E+ QLQ +Y + +E++R+Q ++ + +LE+Q +K +E+
Sbjct: 1595 --EEKRRQLQRQLHEY---ETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREE 1649
Query: 136 -LQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLV 194
+++L + +K Q L+DA+ ++ A++ ++ ++ + L +
Sbjct: 1650 AIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERA 1709
Query: 195 TTMT-LTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRIS 253
L +E+L + S + N Q L + E+ E ++ M ++ R+
Sbjct: 1710 RKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEE--EQGNMEAMSDRVR 1767
Query: 254 QLAENNISLKSEIERLKASVIRTEESALANE---KRLQEKMHEC-AQLGGELDRTRDEAS 309
+ + L +E+ +++ + E + E K L+ K+HE + + T
Sbjct: 1768 KATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALE 1827
Query: 310 RALQRAHEQTETVRKCLQTTVAEL---ERQLAASRAQVSTAEKEREELKNRLHW------ 360
+ + EQ E + Q L +++L QV K E+ K +
Sbjct: 1828 AKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVK 1887
Query: 361 QMKRLTENFEQAQLRILGLQTQVQSLRRTASSTGDGDG 398
Q+KR E E+ RI + ++Q A+ + + G
Sbjct: 1888 QLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMG 1925
Score = 42.3 bits (95), Expect = 0.003
Identities = 90/378 (23%), Positives = 154/378 (40%), Gaps = 46/378 (12%)
Query: 26 KLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQ 85
K+++LE + + N L SKE+ +E + L E E+ L L +
Sbjct: 986 KIKKLEDEILVMDDQNNKL--SKERKLLEE-RISDLTTNLAEEEEKAKNLTKLKNKHESM 1042
Query: 86 LQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQI-NLEIQRVKLKFQ-----EKLQE- 138
+ + V+ + ++ +E + + EQI +L+ Q +LK Q E+LQ
Sbjct: 1043 ISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAA 1102
Query: 139 LAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMT 198
LA + D + LK ++ + E L E AR K R L L T
Sbjct: 1103 LARLDDEIAQKNNALKKIRELEGHISDLQEDLDSE-RAARNKAEKQKRDLGE-ELEALKT 1160
Query: 199 LTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAEN 258
++ L + + R ++Q V VL K ++ E E Q+ + Q+ +Q E
Sbjct: 1161 ELEDTLDSTATQQELRAKREQEVTVLK----KALDE--ETRSHEAQVQEMRQKHAQAVEE 1214
Query: 259 NISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQ 318
+ +R KA+ L K+ EK E A L GEL R L +A ++
Sbjct: 1215 LTEQLEQFKRAKAN--------LDKNKQTLEK--ENADLAGEL--------RVLGQAKQE 1256
Query: 319 TETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHW---QMKRLTENFEQAQLR 375
E +K L+ V EL+ ++ S E+ R EL +++H +++ +T +A+ +
Sbjct: 1257 VEHKKKKLEAQVQELQ-------SKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGK 1309
Query: 376 ILGLQTQVQSLRRTASST 393
+ L V SL T
Sbjct: 1310 AIKLAKDVASLSSQLQDT 1327
Score = 38.3 bits (85), Expect = 0.049
Identities = 58/299 (19%), Positives = 130/299 (43%), Gaps = 23/299 (7%)
Query: 79 MKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQIN------LEIQRVKLKF 132
M+ + D+LQ + + +A+ ++E ++ + EQ+ E + ++++
Sbjct: 861 MQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRL 920
Query: 133 QEKLQELAPIPDLLKATQMRLKD-AQQAQAIAEHNAEQ-LARELNCAREKVVHIFRYLYS 190
K QEL I ++A +D QQ QA + A+Q L E E+ L
Sbjct: 921 AAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEK 980
Query: 191 LYLVTTMTLTQEDL--FGQSQSEIGRGNK--DQTVHVLLHNSLKPPEKPPERGG-DEKQM 245
+ + ++++ +++ + K ++ + L N + EK K
Sbjct: 981 VTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHE 1040
Query: 246 ALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTR 305
+++++ +L + S + E+E+LK + E A +++ + + A+L +L +
Sbjct: 1041 SMISELEVRLKKEEKS-RQELEKLKR---KLEGDASDFHEQIADLQAQIAELKMQLAKKE 1096
Query: 306 DEASRALQRAHEQ----TETVRKC--LQTTVAELERQLAASRAQVSTAEKEREELKNRL 358
+E AL R ++ ++K L+ +++L+ L + RA + AEK++ +L L
Sbjct: 1097 EELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEEL 1155
Score = 33.5 bits (73), Expect = 1.4
Identities = 28/137 (20%), Positives = 62/137 (45%), Gaps = 6/137 (4%)
Query: 242 EKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGEL 301
EK+ L+ +++ E + K E+ER + E ++++ + + +HE + L
Sbjct: 1487 EKETKALS--LARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRAL 1544
Query: 302 DRTRDEASRALQRAHEQ---TETVRKCLQTTVAELERQLAAS-RAQVSTAEKEREELKNR 357
+ +E L+ ++ TE + L+ + L+ Q +A+ E++R +L+ +
Sbjct: 1545 ETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQ 1604
Query: 358 LHWQMKRLTENFEQAQL 374
LH L + +Q L
Sbjct: 1605 LHEYETELEDERKQRAL 1621
Score = 32.7 bits (71), Expect = 2.4
Identities = 35/160 (21%), Positives = 67/160 (41%), Gaps = 4/160 (2%)
Query: 250 QRISQLAENNISLKS---EIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRD 306
+ I QL + +K E+E +AS +A NEK+ + + QL +L
Sbjct: 1649 EAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAER 1708
Query: 307 EASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLT 366
+A E E + L A L+ + A+++ E+E EE + + R+
Sbjct: 1709 ARKQADLEKEELAEELASSLSGRNA-LQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVR 1767
Query: 367 ENFEQAQLRILGLQTQVQSLRRTASSTGDGDGENQECTCK 406
+ +QA+ L T+ + ++ S+ + +N+E K
Sbjct: 1768 KATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSK 1807
>AY520816-1|AAS98910.1| 1979|Homo sapiens smooth muscle myosin heavy
chain isoform SM1 protein.
Length = 1979
Score = 54.4 bits (125), Expect = 7e-07
Identities = 76/370 (20%), Positives = 154/370 (41%), Gaps = 36/370 (9%)
Query: 29 ELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQ- 87
ELE + L L+ SK+ + NV L++ R +++E++T ++E D+LQ
Sbjct: 1508 ELERTNKMLKAEMEDLVSSKDDVGK---NVHELEKSKRALETQMEEMKTQLEELEDELQA 1564
Query: 88 --DYRVKY-LQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPD 144
D +++ + Q L + R N Q+ ++ + + +++ ++ A
Sbjct: 1565 TEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAA 1624
Query: 145 LLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDL 204
K + LKD + A E+ ++L + ++ R L +++++
Sbjct: 1625 AKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDA------RASRDEI 1678
Query: 205 FGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKS 264
F ++ + + + L L E+ ++ EK+ L + S L+ N +L+
Sbjct: 1679 FATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKE-ELAEELASSLSGRN-ALQD 1736
Query: 265 EIERLKASVIRTEE-------SALANEKRLQEKMHECAQLGGELDRTR------DEASRA 311
E RL+A + + EE + A R+++ + QL EL R + A +
Sbjct: 1737 EKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQ 1796
Query: 312 LQRA--------HEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMK 363
L+R HE V+ ++T+A LE ++A QV +E++ L + K
Sbjct: 1797 LERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDK 1856
Query: 364 RLTENFEQAQ 373
+L E Q +
Sbjct: 1857 KLKEILLQVE 1866
Score = 45.6 bits (103), Expect = 3e-04
Identities = 72/380 (18%), Positives = 156/380 (41%), Gaps = 25/380 (6%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTL 78
+ ++ +N+L+ELE K L N+L + E ++ ++E++E+
Sbjct: 874 RQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHE 933
Query: 79 MKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQE 138
M+ + ++ +D + QQL E+++ ++ E+ E R KL+ ++ E
Sbjct: 934 MEARLEEEED------RGQQLQAERKKMAQQMLDLEEQLEEE---EAARQKLQLEKVTAE 984
Query: 139 --LAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYL---YSLYL 193
+ + D + + + + + E L L EK ++ + S+
Sbjct: 985 AKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMIS 1044
Query: 194 VTTMTLTQEDLFGQSQSEIGR---GNKDQTVHVLLHNSLKPPEKPPERGGDEKQM-ALLN 249
+ L +E+ Q ++ R G+ + + E + E+++ A L
Sbjct: 1045 ELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALA 1104
Query: 250 QRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMH-ECAQLGGELDRTRDEA 308
+ ++A+ N +LK +I L+ + +E L +E+ + K + LG EL+ + E
Sbjct: 1105 RLDDEIAQKNNALK-KIRELEGHISDLQED-LDSERAARNKAEKQKRDLGEELEALKTEL 1162
Query: 309 SRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTEN 368
L Q E +R + V L++ L + + E + +E++ + ++ LTE
Sbjct: 1163 EDTLDSTATQQE-LRAKREQEVTVLKKAL---DEETRSHEAQVQEMRQKHAQAVEELTEQ 1218
Query: 369 FEQAQLRILGLQTQVQSLRR 388
EQ + L Q+L +
Sbjct: 1219 LEQFKRAKANLDKNKQTLEK 1238
Score = 44.0 bits (99), Expect = 0.001
Identities = 78/398 (19%), Positives = 162/398 (40%), Gaps = 29/398 (7%)
Query: 22 ETQNKLRELEMKFEGLATHT----NMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRT 77
E + R LE + E + T + L +++ EVN++ALK + + DE
Sbjct: 1536 ELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQN- 1594
Query: 78 LMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQI-NLEIQRVK-LKFQEK 135
+E+ QLQ +Y + +E++R+Q ++ + +LE+Q +K +E+
Sbjct: 1595 --EEKRRQLQRQLHEY---ETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREE 1649
Query: 136 -LQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLV 194
+++L + +K Q L+DA+ ++ A++ ++ ++ + L +
Sbjct: 1650 AIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERA 1709
Query: 195 TTMT-LTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRIS 253
L +E+L + S + N Q L + E+ E ++ M ++ R+
Sbjct: 1710 RKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEE--EQGNMEAMSDRVR 1767
Query: 254 QLAENNISLKSEIERLKASVIRTEESALANE---KRLQEKMHEC-AQLGGELDRTRDEAS 309
+ + L +E+ +++ + E + E K L+ K+HE + + T
Sbjct: 1768 KATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALE 1827
Query: 310 RALQRAHEQTETVRKCLQTTVAEL---ERQLAASRAQVSTAEKEREELKNRLHW------ 360
+ + EQ E + Q L +++L QV K E+ K +
Sbjct: 1828 AKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVK 1887
Query: 361 QMKRLTENFEQAQLRILGLQTQVQSLRRTASSTGDGDG 398
Q+KR E E+ RI + ++Q A+ + + G
Sbjct: 1888 QLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMG 1925
Score = 42.3 bits (95), Expect = 0.003
Identities = 90/378 (23%), Positives = 154/378 (40%), Gaps = 46/378 (12%)
Query: 26 KLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQ 85
K+++LE + + N L SKE+ +E + L E E+ L L +
Sbjct: 986 KIKKLEDEILVMDDQNNKL--SKERKLLEE-RISDLTTNLAEEEEKAKNLTKLKNKHESM 1042
Query: 86 LQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQI-NLEIQRVKLKFQ-----EKLQE- 138
+ + V+ + ++ +E + + EQI +L+ Q +LK Q E+LQ
Sbjct: 1043 ISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAA 1102
Query: 139 LAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMT 198
LA + D + LK ++ + E L E AR K R L L T
Sbjct: 1103 LARLDDEIAQKNNALKKIRELEGHISDLQEDLDSE-RAARNKAEKQKRDLGE-ELEALKT 1160
Query: 199 LTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAEN 258
++ L + + R ++Q V VL K ++ E E Q+ + Q+ +Q E
Sbjct: 1161 ELEDTLDSTATQQELRAKREQEVTVLK----KALDE--ETRSHEAQVQEMRQKHAQAVEE 1214
Query: 259 NISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQ 318
+ +R KA+ L K+ EK E A L GEL R L +A ++
Sbjct: 1215 LTEQLEQFKRAKAN--------LDKNKQTLEK--ENADLAGEL--------RVLGQAKQE 1256
Query: 319 TETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHW---QMKRLTENFEQAQLR 375
E +K L+ V EL+ ++ S E+ R EL +++H +++ +T +A+ +
Sbjct: 1257 VEHKKKKLEAQVQELQ-------SKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGK 1309
Query: 376 ILGLQTQVQSLRRTASST 393
+ L V SL T
Sbjct: 1310 AIKLAKDVASLSSQLQDT 1327
Score = 38.3 bits (85), Expect = 0.049
Identities = 58/299 (19%), Positives = 130/299 (43%), Gaps = 23/299 (7%)
Query: 79 MKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQIN------LEIQRVKLKF 132
M+ + D+LQ + + +A+ ++E ++ + EQ+ E + ++++
Sbjct: 861 MQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRL 920
Query: 133 QEKLQELAPIPDLLKATQMRLKD-AQQAQAIAEHNAEQ-LARELNCAREKVVHIFRYLYS 190
K QEL I ++A +D QQ QA + A+Q L E E+ L
Sbjct: 921 AAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEK 980
Query: 191 LYLVTTMTLTQEDL--FGQSQSEIGRGNK--DQTVHVLLHNSLKPPEKPPERGG-DEKQM 245
+ + ++++ +++ + K ++ + L N + EK K
Sbjct: 981 VTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHE 1040
Query: 246 ALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTR 305
+++++ +L + S + E+E+LK + E A +++ + + A+L +L +
Sbjct: 1041 SMISELEVRLKKEEKS-RQELEKLKR---KLEGDASDFHEQIADLQAQIAELKMQLAKKE 1096
Query: 306 DEASRALQRAHEQ----TETVRKC--LQTTVAELERQLAASRAQVSTAEKEREELKNRL 358
+E AL R ++ ++K L+ +++L+ L + RA + AEK++ +L L
Sbjct: 1097 EELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEEL 1155
Score = 33.5 bits (73), Expect = 1.4
Identities = 28/137 (20%), Positives = 62/137 (45%), Gaps = 6/137 (4%)
Query: 242 EKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGEL 301
EK+ L+ +++ E + K E+ER + E ++++ + + +HE + L
Sbjct: 1487 EKETKALS--LARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRAL 1544
Query: 302 DRTRDEASRALQRAHEQ---TETVRKCLQTTVAELERQLAAS-RAQVSTAEKEREELKNR 357
+ +E L+ ++ TE + L+ + L+ Q +A+ E++R +L+ +
Sbjct: 1545 ETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQ 1604
Query: 358 LHWQMKRLTENFEQAQL 374
LH L + +Q L
Sbjct: 1605 LHEYETELEDERKQRAL 1621
Score = 32.7 bits (71), Expect = 2.4
Identities = 35/160 (21%), Positives = 67/160 (41%), Gaps = 4/160 (2%)
Query: 250 QRISQLAENNISLKS---EIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRD 306
+ I QL + +K E+E +AS +A NEK+ + + QL +L
Sbjct: 1649 EAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAER 1708
Query: 307 EASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLT 366
+A E E + L A L+ + A+++ E+E EE + + R+
Sbjct: 1709 ARKQADLEKEELAEELASSLSGRNA-LQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVR 1767
Query: 367 ENFEQAQLRILGLQTQVQSLRRTASSTGDGDGENQECTCK 406
+ +QA+ L T+ + ++ S+ + +N+E K
Sbjct: 1768 KATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSK 1807
>AF001548-1|AAC31665.1| 1857|Homo sapiens Myosin heavy chain (MHY11)
(5'partial) protein.
Length = 1857
Score = 54.4 bits (125), Expect = 7e-07
Identities = 76/370 (20%), Positives = 154/370 (41%), Gaps = 36/370 (9%)
Query: 29 ELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQ- 87
ELE + L L+ SK+ + NV L++ R +++E++T ++E D+LQ
Sbjct: 1386 ELERTNKMLKAEMEDLVSSKDDVGK---NVHELEKSKRALETQMEEMKTQLEELEDELQA 1442
Query: 88 --DYRVKY-LQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPD 144
D +++ + Q L + R N Q+ ++ + + +++ ++ A
Sbjct: 1443 TEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAA 1502
Query: 145 LLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDL 204
K + LKD + A E+ ++L + ++ R L +++++
Sbjct: 1503 AKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDA------RASRDEI 1556
Query: 205 FGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKS 264
F ++ + + + L L E+ ++ EK+ L + S L+ N +L+
Sbjct: 1557 FATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKE-ELAEELASSLSGRN-ALQD 1614
Query: 265 EIERLKASVIRTEE-------SALANEKRLQEKMHECAQLGGELDRTR------DEASRA 311
E RL+A + + EE + A R+++ + QL EL R + A +
Sbjct: 1615 EKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQ 1674
Query: 312 LQRA--------HEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMK 363
L+R HE V+ ++T+A LE ++A QV +E++ L + K
Sbjct: 1675 LERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDK 1734
Query: 364 RLTENFEQAQ 373
+L E Q +
Sbjct: 1735 KLKEILLQVE 1744
Score = 45.6 bits (103), Expect = 3e-04
Identities = 72/380 (18%), Positives = 156/380 (41%), Gaps = 25/380 (6%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTL 78
+ ++ +N+L+ELE K L N+L + E ++ ++E++E+
Sbjct: 752 RQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHE 811
Query: 79 MKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQE 138
M+ + ++ +D + QQL E+++ ++ E+ E R KL+ ++ E
Sbjct: 812 MEARLEEEED------RGQQLQAERKKMAQQMLDLEEQLEEE---EAARQKLQLEKVTAE 862
Query: 139 --LAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYL---YSLYL 193
+ + D + + + + + E L L EK ++ + S+
Sbjct: 863 AKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMIS 922
Query: 194 VTTMTLTQEDLFGQSQSEIGR---GNKDQTVHVLLHNSLKPPEKPPERGGDEKQM-ALLN 249
+ L +E+ Q ++ R G+ + + E + E+++ A L
Sbjct: 923 ELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALA 982
Query: 250 QRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMH-ECAQLGGELDRTRDEA 308
+ ++A+ N +LK +I L+ + +E L +E+ + K + LG EL+ + E
Sbjct: 983 RLDDEIAQKNNALK-KIRELEGHISDLQED-LDSERAARNKAEKQKRDLGEELEALKTEL 1040
Query: 309 SRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTEN 368
L Q E +R + V L++ L + + E + +E++ + ++ LTE
Sbjct: 1041 EDTLDSTATQQE-LRAKREQEVTVLKKAL---DEETRSHEAQVQEMRQKHAQAVEELTEQ 1096
Query: 369 FEQAQLRILGLQTQVQSLRR 388
EQ + L Q+L +
Sbjct: 1097 LEQFKRAKANLDKNKQTLEK 1116
Score = 44.0 bits (99), Expect = 0.001
Identities = 78/398 (19%), Positives = 162/398 (40%), Gaps = 29/398 (7%)
Query: 22 ETQNKLRELEMKFEGLATHT----NMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRT 77
E + R LE + E + T + L +++ EVN++ALK + + DE
Sbjct: 1414 ELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQN- 1472
Query: 78 LMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQI-NLEIQRVK-LKFQEK 135
+E+ QLQ +Y + +E++R+Q ++ + +LE+Q +K +E+
Sbjct: 1473 --EEKRRQLQRQLHEY---ETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREE 1527
Query: 136 -LQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLV 194
+++L + +K Q L+DA+ ++ A++ ++ ++ + L +
Sbjct: 1528 AIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERA 1587
Query: 195 TTMT-LTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRIS 253
L +E+L + S + N Q L + E+ E ++ M ++ R+
Sbjct: 1588 RKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEE--EQGNMEAMSDRVR 1645
Query: 254 QLAENNISLKSEIERLKASVIRTEESALANE---KRLQEKMHEC-AQLGGELDRTRDEAS 309
+ + L +E+ +++ + E + E K L+ K+HE + + T
Sbjct: 1646 KATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALE 1705
Query: 310 RALQRAHEQTETVRKCLQTTVAEL---ERQLAASRAQVSTAEKEREELKNRLHW------ 360
+ + EQ E + Q L +++L QV K E+ K +
Sbjct: 1706 AKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVK 1765
Query: 361 QMKRLTENFEQAQLRILGLQTQVQSLRRTASSTGDGDG 398
Q+KR E E+ RI + ++Q A+ + + G
Sbjct: 1766 QLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMG 1803
Score = 42.3 bits (95), Expect = 0.003
Identities = 90/378 (23%), Positives = 154/378 (40%), Gaps = 46/378 (12%)
Query: 26 KLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQ 85
K+++LE + + N L SKE+ +E + L E E+ L L +
Sbjct: 864 KIKKLEDEILVMDDQNNKL--SKERKLLEE-RISDLTTNLAEEEEKAKNLTKLKNKHESM 920
Query: 86 LQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQI-NLEIQRVKLKFQ-----EKLQE- 138
+ + V+ + ++ +E + + EQI +L+ Q +LK Q E+LQ
Sbjct: 921 ISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAA 980
Query: 139 LAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMT 198
LA + D + LK ++ + E L E AR K R L L T
Sbjct: 981 LARLDDEIAQKNNALKKIRELEGHISDLQEDLDSE-RAARNKAEKQKRDLGE-ELEALKT 1038
Query: 199 LTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAEN 258
++ L + + R ++Q V VL K ++ E E Q+ + Q+ +Q E
Sbjct: 1039 ELEDTLDSTATQQELRAKREQEVTVLK----KALDE--ETRSHEAQVQEMRQKHAQAVEE 1092
Query: 259 NISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQ 318
+ +R KA+ L K+ EK E A L GEL R L +A ++
Sbjct: 1093 LTEQLEQFKRAKAN--------LDKNKQTLEK--ENADLAGEL--------RVLGQAKQE 1134
Query: 319 TETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHW---QMKRLTENFEQAQLR 375
E +K L+ V EL+ ++ S E+ R EL +++H +++ +T +A+ +
Sbjct: 1135 VEHKKKKLEAQVQELQ-------SKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGK 1187
Query: 376 ILGLQTQVQSLRRTASST 393
+ L V SL T
Sbjct: 1188 AIKLAKDVASLSSQLQDT 1205
Score = 38.3 bits (85), Expect = 0.049
Identities = 58/299 (19%), Positives = 130/299 (43%), Gaps = 23/299 (7%)
Query: 79 MKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQIN------LEIQRVKLKF 132
M+ + D+LQ + + +A+ ++E ++ + EQ+ E + ++++
Sbjct: 739 MQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRL 798
Query: 133 QEKLQELAPIPDLLKATQMRLKD-AQQAQAIAEHNAEQ-LARELNCAREKVVHIFRYLYS 190
K QEL I ++A +D QQ QA + A+Q L E E+ L
Sbjct: 799 AAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEK 858
Query: 191 LYLVTTMTLTQEDL--FGQSQSEIGRGNK--DQTVHVLLHNSLKPPEKPPERGG-DEKQM 245
+ + ++++ +++ + K ++ + L N + EK K
Sbjct: 859 VTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHE 918
Query: 246 ALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTR 305
+++++ +L + S + E+E+LK + E A +++ + + A+L +L +
Sbjct: 919 SMISELEVRLKKEEKS-RQELEKLKR---KLEGDASDFHEQIADLQAQIAELKMQLAKKE 974
Query: 306 DEASRALQRAHEQ----TETVRKC--LQTTVAELERQLAASRAQVSTAEKEREELKNRL 358
+E AL R ++ ++K L+ +++L+ L + RA + AEK++ +L L
Sbjct: 975 EELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEEL 1033
Score = 33.5 bits (73), Expect = 1.4
Identities = 28/137 (20%), Positives = 62/137 (45%), Gaps = 6/137 (4%)
Query: 242 EKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGEL 301
EK+ L+ +++ E + K E+ER + E ++++ + + +HE + L
Sbjct: 1365 EKETKALS--LARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRAL 1422
Query: 302 DRTRDEASRALQRAHEQ---TETVRKCLQTTVAELERQLAAS-RAQVSTAEKEREELKNR 357
+ +E L+ ++ TE + L+ + L+ Q +A+ E++R +L+ +
Sbjct: 1423 ETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQ 1482
Query: 358 LHWQMKRLTENFEQAQL 374
LH L + +Q L
Sbjct: 1483 LHEYETELEDERKQRAL 1499
Score = 32.7 bits (71), Expect = 2.4
Identities = 35/160 (21%), Positives = 67/160 (41%), Gaps = 4/160 (2%)
Query: 250 QRISQLAENNISLKS---EIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRD 306
+ I QL + +K E+E +AS +A NEK+ + + QL +L
Sbjct: 1527 EAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAER 1586
Query: 307 EASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLT 366
+A E E + L A L+ + A+++ E+E EE + + R+
Sbjct: 1587 ARKQADLEKEELAEELASSLSGRNA-LQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVR 1645
Query: 367 ENFEQAQLRILGLQTQVQSLRRTASSTGDGDGENQECTCK 406
+ +QA+ L T+ + ++ S+ + +N+E K
Sbjct: 1646 KATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSK 1685
>AB020673-1|BAA74889.2| 1984|Homo sapiens KIAA0866 protein protein.
Length = 1984
Score = 54.4 bits (125), Expect = 7e-07
Identities = 76/370 (20%), Positives = 154/370 (41%), Gaps = 36/370 (9%)
Query: 29 ELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQ- 87
ELE + L L+ SK+ + NV L++ R +++E++T ++E D+LQ
Sbjct: 1513 ELERTNKMLKAEMEDLVSSKDDVGK---NVHELEKSKRALETQMEEMKTQLEELEDELQA 1569
Query: 88 --DYRVKY-LQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPD 144
D +++ + Q L + R N Q+ ++ + + +++ ++ A
Sbjct: 1570 TEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAA 1629
Query: 145 LLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDL 204
K + LKD + A E+ ++L + ++ R L +++++
Sbjct: 1630 AKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDA------RASRDEI 1683
Query: 205 FGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKS 264
F ++ + + + L L E+ ++ EK+ L + S L+ N +L+
Sbjct: 1684 FATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKE-ELAEELASSLSGRN-ALQD 1741
Query: 265 EIERLKASVIRTEE-------SALANEKRLQEKMHECAQLGGELDRTR------DEASRA 311
E RL+A + + EE + A R+++ + QL EL R + A +
Sbjct: 1742 EKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQ 1801
Query: 312 LQRA--------HEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMK 363
L+R HE V+ ++T+A LE ++A QV +E++ L + K
Sbjct: 1802 LERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDK 1861
Query: 364 RLTENFEQAQ 373
+L E Q +
Sbjct: 1862 KLKEILLQVE 1871
Score = 45.6 bits (103), Expect = 3e-04
Identities = 72/380 (18%), Positives = 156/380 (41%), Gaps = 25/380 (6%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTL 78
+ ++ +N+L+ELE K L N+L + E ++ ++E++E+
Sbjct: 879 RQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHE 938
Query: 79 MKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQE 138
M+ + ++ +D + QQL E+++ ++ E+ E R KL+ ++ E
Sbjct: 939 MEARLEEEED------RGQQLQAERKKMAQQMLDLEEQLEEE---EAARQKLQLEKVTAE 989
Query: 139 --LAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYL---YSLYL 193
+ + D + + + + + E L L EK ++ + S+
Sbjct: 990 AKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMIS 1049
Query: 194 VTTMTLTQEDLFGQSQSEIGR---GNKDQTVHVLLHNSLKPPEKPPERGGDEKQM-ALLN 249
+ L +E+ Q ++ R G+ + + E + E+++ A L
Sbjct: 1050 ELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALA 1109
Query: 250 QRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMH-ECAQLGGELDRTRDEA 308
+ ++A+ N +LK +I L+ + +E L +E+ + K + LG EL+ + E
Sbjct: 1110 RLDDEIAQKNNALK-KIRELEGHISDLQED-LDSERAARNKAEKQKRDLGEELEALKTEL 1167
Query: 309 SRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTEN 368
L Q E +R + V L++ L + + E + +E++ + ++ LTE
Sbjct: 1168 EDTLDSTATQQE-LRAKREQEVTVLKKAL---DEETRSHEAQVQEMRQKHAQAVEELTEQ 1223
Query: 369 FEQAQLRILGLQTQVQSLRR 388
EQ + L Q+L +
Sbjct: 1224 LEQFKRAKANLDKNKQTLEK 1243
Score = 44.0 bits (99), Expect = 0.001
Identities = 78/398 (19%), Positives = 162/398 (40%), Gaps = 29/398 (7%)
Query: 22 ETQNKLRELEMKFEGLATHT----NMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRT 77
E + R LE + E + T + L +++ EVN++ALK + + DE
Sbjct: 1541 ELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQN- 1599
Query: 78 LMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQI-NLEIQRVK-LKFQEK 135
+E+ QLQ +Y + +E++R+Q ++ + +LE+Q +K +E+
Sbjct: 1600 --EEKRRQLQRQLHEY---ETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREE 1654
Query: 136 -LQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLV 194
+++L + +K Q L+DA+ ++ A++ ++ ++ + L +
Sbjct: 1655 AIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERA 1714
Query: 195 TTMT-LTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRIS 253
L +E+L + S + N Q L + E+ E ++ M ++ R+
Sbjct: 1715 RKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEE--EQGNMEAMSDRVR 1772
Query: 254 QLAENNISLKSEIERLKASVIRTEESALANE---KRLQEKMHEC-AQLGGELDRTRDEAS 309
+ + L +E+ +++ + E + E K L+ K+HE + + T
Sbjct: 1773 KATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALE 1832
Query: 310 RALQRAHEQTETVRKCLQTTVAEL---ERQLAASRAQVSTAEKEREELKNRLHW------ 360
+ + EQ E + Q L +++L QV K E+ K +
Sbjct: 1833 AKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVK 1892
Query: 361 QMKRLTENFEQAQLRILGLQTQVQSLRRTASSTGDGDG 398
Q+KR E E+ RI + ++Q A+ + + G
Sbjct: 1893 QLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMG 1930
Score = 42.3 bits (95), Expect = 0.003
Identities = 90/378 (23%), Positives = 154/378 (40%), Gaps = 46/378 (12%)
Query: 26 KLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQ 85
K+++LE + + N L SKE+ +E + L E E+ L L +
Sbjct: 991 KIKKLEDEILVMDDQNNKL--SKERKLLEE-RISDLTTNLAEEEEKAKNLTKLKNKHESM 1047
Query: 86 LQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQI-NLEIQRVKLKFQ-----EKLQE- 138
+ + V+ + ++ +E + + EQI +L+ Q +LK Q E+LQ
Sbjct: 1048 ISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAA 1107
Query: 139 LAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMT 198
LA + D + LK ++ + E L E AR K R L L T
Sbjct: 1108 LARLDDEIAQKNNALKKIRELEGHISDLQEDLDSE-RAARNKAEKQKRDLGE-ELEALKT 1165
Query: 199 LTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAEN 258
++ L + + R ++Q V VL K ++ E E Q+ + Q+ +Q E
Sbjct: 1166 ELEDTLDSTATQQELRAKREQEVTVLK----KALDE--ETRSHEAQVQEMRQKHAQAVEE 1219
Query: 259 NISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQ 318
+ +R KA+ L K+ EK E A L GEL R L +A ++
Sbjct: 1220 LTEQLEQFKRAKAN--------LDKNKQTLEK--ENADLAGEL--------RVLGQAKQE 1261
Query: 319 TETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHW---QMKRLTENFEQAQLR 375
E +K L+ V EL+ ++ S E+ R EL +++H +++ +T +A+ +
Sbjct: 1262 VEHKKKKLEAQVQELQ-------SKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGK 1314
Query: 376 ILGLQTQVQSLRRTASST 393
+ L V SL T
Sbjct: 1315 AIKLAKDVASLSSQLQDT 1332
Score = 38.3 bits (85), Expect = 0.049
Identities = 58/299 (19%), Positives = 130/299 (43%), Gaps = 23/299 (7%)
Query: 79 MKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQIN------LEIQRVKLKF 132
M+ + D+LQ + + +A+ ++E ++ + EQ+ E + ++++
Sbjct: 866 MQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRL 925
Query: 133 QEKLQELAPIPDLLKATQMRLKD-AQQAQAIAEHNAEQ-LARELNCAREKVVHIFRYLYS 190
K QEL I ++A +D QQ QA + A+Q L E E+ L
Sbjct: 926 AAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEK 985
Query: 191 LYLVTTMTLTQEDL--FGQSQSEIGRGNK--DQTVHVLLHNSLKPPEKPPERGG-DEKQM 245
+ + ++++ +++ + K ++ + L N + EK K
Sbjct: 986 VTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHE 1045
Query: 246 ALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTR 305
+++++ +L + S + E+E+LK + E A +++ + + A+L +L +
Sbjct: 1046 SMISELEVRLKKEEKS-RQELEKLKR---KLEGDASDFHEQIADLQAQIAELKMQLAKKE 1101
Query: 306 DEASRALQRAHEQ----TETVRKC--LQTTVAELERQLAASRAQVSTAEKEREELKNRL 358
+E AL R ++ ++K L+ +++L+ L + RA + AEK++ +L L
Sbjct: 1102 EELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEEL 1160
Score = 33.5 bits (73), Expect = 1.4
Identities = 28/137 (20%), Positives = 62/137 (45%), Gaps = 6/137 (4%)
Query: 242 EKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGEL 301
EK+ L+ +++ E + K E+ER + E ++++ + + +HE + L
Sbjct: 1492 EKETKALS--LARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRAL 1549
Query: 302 DRTRDEASRALQRAHEQ---TETVRKCLQTTVAELERQLAAS-RAQVSTAEKEREELKNR 357
+ +E L+ ++ TE + L+ + L+ Q +A+ E++R +L+ +
Sbjct: 1550 ETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQ 1609
Query: 358 LHWQMKRLTENFEQAQL 374
LH L + +Q L
Sbjct: 1610 LHEYETELEDERKQRAL 1626
Score = 32.7 bits (71), Expect = 2.4
Identities = 35/160 (21%), Positives = 67/160 (41%), Gaps = 4/160 (2%)
Query: 250 QRISQLAENNISLKS---EIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRD 306
+ I QL + +K E+E +AS +A NEK+ + + QL +L
Sbjct: 1654 EAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAER 1713
Query: 307 EASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLT 366
+A E E + L A L+ + A+++ E+E EE + + R+
Sbjct: 1714 ARKQADLEKEELAEELASSLSGRNA-LQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVR 1772
Query: 367 ENFEQAQLRILGLQTQVQSLRRTASSTGDGDGENQECTCK 406
+ +QA+ L T+ + ++ S+ + +N+E K
Sbjct: 1773 KATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSK 1812
>AY648038-1|AAT67172.1| 1551|Homo sapiens myotonic dystrophy
kinase-related CDC42-binding kinase gamma protein.
Length = 1551
Score = 53.6 bits (123), Expect = 1e-06
Identities = 79/303 (26%), Positives = 131/303 (43%), Gaps = 37/303 (12%)
Query: 119 EQINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAR 178
++++ E+ + Q + QEL + RL++AQ+ +A L+ +L AR
Sbjct: 492 DRLHRELAEGRAGLQAQEQELCRAQGQQEELLQRLQEAQEREAATASQTRALSSQLEEAR 551
Query: 179 EKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLH-NSLKPPEKPPE 237
+ + SL + +TQ L GQ + + ++ +T+H N + PPE P+
Sbjct: 552 AAQRELEAQVSSL----SRQVTQ--LQGQWEQRLEESSQAKTIHTASETNGMGPPEGGPQ 605
Query: 238 RGGDEKQMALLNQRIS---------------QLAENNISLKSEIERLKASVIRTEES--A 280
K++A L +++ QL E N L E ERL+A + + +ES
Sbjct: 606 EAQLRKEVAALREQLEQAHSHRRSGKEEALCQLQEENRRLSREQERLEAELAQEQESKQR 665
Query: 281 LANEKRLQEKMHECAQLGGELDRTRDE-ASRALQRA-----HEQTETVRKC-LQTTVAE- 332
L E+R E E AQL L DE SR +A E+ E++R QT A
Sbjct: 666 LEGERRETESNWE-AQLADILSWVNDEKVSRGYLQALATKMAEELESLRNVGTQTLPARP 724
Query: 333 LERQLAASRAQVSTAEKEREELKNRLHWQMKR---LTENFEQAQLRILGLQTQVQSLRRT 389
L+ Q A R Q A R EL++ L +++ L E Q Q L + ++Q +
Sbjct: 725 LDHQWKARRLQKMEA-SARLELQSALEAEIRAKQGLQERLTQVQEAQLQAERRLQEAEKQ 783
Query: 390 ASS 392
+ +
Sbjct: 784 SQA 786
>AY319414-1|AAP83847.1| 657|Homo sapiens outer dense fiber of sperm
tails 2 isoform 3 protein.
Length = 657
Score = 53.6 bits (123), Expect = 1e-06
Identities = 34/155 (21%), Positives = 71/155 (45%), Gaps = 2/155 (1%)
Query: 19 QHRETQNKLRE-LEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRT 77
Q + + K+RE + E L T K + + + ++ +A E+ +L+
Sbjct: 475 QQQTLEEKMREDRDSLVERLHRQTAEYSAFKLENERLKASFAPMEDKLNQAHLEVQQLKA 534
Query: 78 LMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQ 137
+K + +Y+ + ++ + +E Q N + +++N EI+ + +FQ +L
Sbjct: 535 SVKNYEGMIDNYKSQVMKTRLEADEVAAQLERCDKENKILKDEMNKEIEAARRQFQSQLA 594
Query: 138 ELAPIPDLLKATQMRLKDAQ-QAQAIAEHNAEQLA 171
+L +PD+LK T+ +L + Q Q Q N + A
Sbjct: 595 DLQQLPDILKITEAKLAECQDQLQGYERKNIDLTA 629
Score = 35.1 bits (77), Expect = 0.46
Identities = 72/364 (19%), Positives = 145/364 (39%), Gaps = 22/364 (6%)
Query: 20 HRETQNKLRELEMK--FEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRT 77
+R ++ LRE K E L L+ +A ++ + L Q + +E++EL
Sbjct: 267 NRTLRDLLREQHCKEDSERLMEQQGALLKRLAEADSEKARLLLLLQ---DKDKEVEELLQ 323
Query: 78 LMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQI-NLEIQ--RVKLKFQE 134
++ + Q + + + + Q N+R+ QI NLE + K + +
Sbjct: 324 EIQCEKAQAKTASELSKSMESMRGHLQAQLRSKEAENSRLCMQIKNLERSGNQHKAEVEA 383
Query: 135 KLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLV 194
+++L + + LK A +AQ +E+ A +L H+ LY+
Sbjct: 384 IMEQLKELKQKGDRDKESLKKAIRAQKERAEKSEEYAEQL--------HVQLADKDLYVA 435
Query: 195 TTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHN--SLKPPEKPPERGGDEKQMALLNQRI 252
++ + +Q +G+ + + VL L ++ E E + +L+ +
Sbjct: 436 EALSTLESWRSRYNQVVKEKGDLELEIIVLNDRVTDLVNQQQTLEEKMREDRDSLVERLH 495
Query: 253 SQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRAL 312
Q AE + + K E ERLKAS E+ +Q+ G +D + + +
Sbjct: 496 RQTAEYS-AFKLENERLKASFAPMEDKLNQAHLEVQQLKASVKNYEGMIDNYKSQVMKTR 554
Query: 313 QRAHEQTETVRKCLQTTVA---ELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENF 369
A E + +C + E+ +++ A+R Q + + ++L + L +L E
Sbjct: 555 LEADEVAAQLERCDKENKILKDEMNKEIEAARRQFQSQLADLQQLPDILKITEAKLAECQ 614
Query: 370 EQAQ 373
+Q Q
Sbjct: 615 DQLQ 618
Score = 33.9 bits (74), Expect = 1.1
Identities = 35/146 (23%), Positives = 61/146 (41%), Gaps = 10/146 (6%)
Query: 244 QMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQ------- 296
+M +++I L LKSE++ K + ++ L+E HE A+
Sbjct: 119 KMNRYDKKIDSLMNAVGCLKSEVKMQKGERQMAKRFLEERKEELEEVAHELAETEHENTV 178
Query: 297 LGGELDRTRDEAS-RALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELK 355
L ++R ++E LQ+ H Q E ++CL + + E E AA+ QV + +LK
Sbjct: 179 LRHNIERMKEEKDFTRLQKKHLQQE--KECLMSKLVEAEMDGAAAAKQVMALKDTIGKLK 236
Query: 356 NRLHWQMKRLTENFEQAQLRILGLQT 381
+ Q +L + L T
Sbjct: 237 TEKQMTCTDINTLTRQKELLLQKLST 262
>AL445287-4|CAH71067.1| 638|Homo sapiens outer dense fiber of sperm
tails 2 protein.
Length = 638
Score = 53.6 bits (123), Expect = 1e-06
Identities = 34/155 (21%), Positives = 71/155 (45%), Gaps = 2/155 (1%)
Query: 19 QHRETQNKLRE-LEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRT 77
Q + + K+RE + E L T K + + + ++ +A E+ +L+
Sbjct: 456 QQQTLEEKMREDRDSLVERLHRQTAEYSAFKLENERLKASFAPMEDKLNQAHLEVQQLKA 515
Query: 78 LMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQ 137
+K + +Y+ + ++ + +E Q N + +++N EI+ + +FQ +L
Sbjct: 516 SVKNYEGMIDNYKSQVMKTRLEADEVAAQLERCDKENKILKDEMNKEIEAARRQFQSQLA 575
Query: 138 ELAPIPDLLKATQMRLKDAQ-QAQAIAEHNAEQLA 171
+L +PD+LK T+ +L + Q Q Q N + A
Sbjct: 576 DLQQLPDILKITEAKLAECQDQLQGYERKNIDLTA 610
Score = 35.1 bits (77), Expect = 0.46
Identities = 72/364 (19%), Positives = 145/364 (39%), Gaps = 22/364 (6%)
Query: 20 HRETQNKLRELEMK--FEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRT 77
+R ++ LRE K E L L+ +A ++ + L Q + +E++EL
Sbjct: 248 NRTLRDLLREQHCKEDSERLMEQQGALLKRLAEADSEKARLLLLLQ---DKDKEVEELLQ 304
Query: 78 LMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQI-NLEIQ--RVKLKFQE 134
++ + Q + + + + Q N+R+ QI NLE + K + +
Sbjct: 305 EIQCEKAQAKTASELSKSMESMRGHLQAQLRSKEAENSRLCMQIKNLERSGNQHKAEVEA 364
Query: 135 KLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLV 194
+++L + + LK A +AQ +E+ A +L H+ LY+
Sbjct: 365 IMEQLKELKQKGDRDKESLKKAIRAQKERAEKSEEYAEQL--------HVQLADKDLYVA 416
Query: 195 TTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHN--SLKPPEKPPERGGDEKQMALLNQRI 252
++ + +Q +G+ + + VL L ++ E E + +L+ +
Sbjct: 417 EALSTLESWRSRYNQVVKEKGDLELEIIVLNDRVTDLVNQQQTLEEKMREDRDSLVERLH 476
Query: 253 SQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRAL 312
Q AE + + K E ERLKAS E+ +Q+ G +D + + +
Sbjct: 477 RQTAEYS-AFKLENERLKASFAPMEDKLNQAHLEVQQLKASVKNYEGMIDNYKSQVMKTR 535
Query: 313 QRAHEQTETVRKCLQTTVA---ELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENF 369
A E + +C + E+ +++ A+R Q + + ++L + L +L E
Sbjct: 536 LEADEVAAQLERCDKENKILKDEMNKEIEAARRQFQSQLADLQQLPDILKITEAKLAECQ 595
Query: 370 EQAQ 373
+Q Q
Sbjct: 596 DQLQ 599
Score = 33.9 bits (74), Expect = 1.1
Identities = 35/146 (23%), Positives = 61/146 (41%), Gaps = 10/146 (6%)
Query: 244 QMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQ------- 296
+M +++I L LKSE++ K + ++ L+E HE A+
Sbjct: 100 KMNRYDKKIDSLMNAVGCLKSEVKMQKGERQMAKRFLEERKEELEEVAHELAETEHENTV 159
Query: 297 LGGELDRTRDEAS-RALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELK 355
L ++R ++E LQ+ H Q E ++CL + + E E AA+ QV + +LK
Sbjct: 160 LRHNIERMKEEKDFTILQKKHLQQE--KECLMSKLVEAEMDGAAAAKQVMALKDTIGKLK 217
Query: 356 NRLHWQMKRLTENFEQAQLRILGLQT 381
+ Q +L + L T
Sbjct: 218 TEKQMTCTDINTLTRQKELLLQKLST 243
>AL445287-3|CAH71066.1| 701|Homo sapiens outer dense fiber of sperm
tails 2 protein.
Length = 701
Score = 53.6 bits (123), Expect = 1e-06
Identities = 34/155 (21%), Positives = 71/155 (45%), Gaps = 2/155 (1%)
Query: 19 QHRETQNKLRE-LEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRT 77
Q + + K+RE + E L T K + + + ++ +A E+ +L+
Sbjct: 519 QQQTLEEKMREDRDSLVERLHRQTAEYSAFKLENERLKASFAPMEDKLNQAHLEVQQLKA 578
Query: 78 LMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQ 137
+K + +Y+ + ++ + +E Q N + +++N EI+ + +FQ +L
Sbjct: 579 SVKNYEGMIDNYKSQVMKTRLEADEVAAQLERCDKENKILKDEMNKEIEAARRQFQSQLA 638
Query: 138 ELAPIPDLLKATQMRLKDAQ-QAQAIAEHNAEQLA 171
+L +PD+LK T+ +L + Q Q Q N + A
Sbjct: 639 DLQQLPDILKITEAKLAECQDQLQGYERKNIDLTA 673
Score = 35.1 bits (77), Expect = 0.46
Identities = 72/364 (19%), Positives = 145/364 (39%), Gaps = 22/364 (6%)
Query: 20 HRETQNKLRELEMK--FEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRT 77
+R ++ LRE K E L L+ +A ++ + L Q + +E++EL
Sbjct: 311 NRTLRDLLREQHCKEDSERLMEQQGALLKRLAEADSEKARLLLLLQ---DKDKEVEELLQ 367
Query: 78 LMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQI-NLEIQ--RVKLKFQE 134
++ + Q + + + + Q N+R+ QI NLE + K + +
Sbjct: 368 EIQCEKAQAKTASELSKSMESMRGHLQAQLRSKEAENSRLCMQIKNLERSGNQHKAEVEA 427
Query: 135 KLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLV 194
+++L + + LK A +AQ +E+ A +L H+ LY+
Sbjct: 428 IMEQLKELKQKGDRDKESLKKAIRAQKERAEKSEEYAEQL--------HVQLADKDLYVA 479
Query: 195 TTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHN--SLKPPEKPPERGGDEKQMALLNQRI 252
++ + +Q +G+ + + VL L ++ E E + +L+ +
Sbjct: 480 EALSTLESWRSRYNQVVKEKGDLELEIIVLNDRVTDLVNQQQTLEEKMREDRDSLVERLH 539
Query: 253 SQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRAL 312
Q AE + + K E ERLKAS E+ +Q+ G +D + + +
Sbjct: 540 RQTAEYS-AFKLENERLKASFAPMEDKLNQAHLEVQQLKASVKNYEGMIDNYKSQVMKTR 598
Query: 313 QRAHEQTETVRKCLQTTVA---ELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENF 369
A E + +C + E+ +++ A+R Q + + ++L + L +L E
Sbjct: 599 LEADEVAAQLERCDKENKILKDEMNKEIEAARRQFQSQLADLQQLPDILKITEAKLAECQ 658
Query: 370 EQAQ 373
+Q Q
Sbjct: 659 DQLQ 662
Score = 33.9 bits (74), Expect = 1.1
Identities = 35/146 (23%), Positives = 61/146 (41%), Gaps = 10/146 (6%)
Query: 244 QMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQ------- 296
+M +++I L LKSE++ K + ++ L+E HE A+
Sbjct: 163 KMNRYDKKIDSLMNAVGCLKSEVKMQKGERQMAKRFLEERKEELEEVAHELAETEHENTV 222
Query: 297 LGGELDRTRDEAS-RALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELK 355
L ++R ++E LQ+ H Q E ++CL + + E E AA+ QV + +LK
Sbjct: 223 LRHNIERMKEEKDFTILQKKHLQQE--KECLMSKLVEAEMDGAAAAKQVMALKDTIGKLK 280
Query: 356 NRLHWQMKRLTENFEQAQLRILGLQT 381
+ Q +L + L T
Sbjct: 281 TEKQMTCTDINTLTRQKELLLQKLST 306
>AL359091-17|CAI13500.1| 638|Homo sapiens outer dense fiber of
sperm tails 2 protein.
Length = 638
Score = 53.6 bits (123), Expect = 1e-06
Identities = 34/155 (21%), Positives = 71/155 (45%), Gaps = 2/155 (1%)
Query: 19 QHRETQNKLRE-LEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRT 77
Q + + K+RE + E L T K + + + ++ +A E+ +L+
Sbjct: 456 QQQTLEEKMREDRDSLVERLHRQTAEYSAFKLENERLKASFAPMEDKLNQAHLEVQQLKA 515
Query: 78 LMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQ 137
+K + +Y+ + ++ + +E Q N + +++N EI+ + +FQ +L
Sbjct: 516 SVKNYEGMIDNYKSQVMKTRLEADEVAAQLERCDKENKILKDEMNKEIEAARRQFQSQLA 575
Query: 138 ELAPIPDLLKATQMRLKDAQ-QAQAIAEHNAEQLA 171
+L +PD+LK T+ +L + Q Q Q N + A
Sbjct: 576 DLQQLPDILKITEAKLAECQDQLQGYERKNIDLTA 610
Score = 35.1 bits (77), Expect = 0.46
Identities = 72/364 (19%), Positives = 145/364 (39%), Gaps = 22/364 (6%)
Query: 20 HRETQNKLRELEMK--FEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRT 77
+R ++ LRE K E L L+ +A ++ + L Q + +E++EL
Sbjct: 248 NRTLRDLLREQHCKEDSERLMEQQGALLKRLAEADSEKARLLLLLQ---DKDKEVEELLQ 304
Query: 78 LMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQI-NLEIQ--RVKLKFQE 134
++ + Q + + + + Q N+R+ QI NLE + K + +
Sbjct: 305 EIQCEKAQAKTASELSKSMESMRGHLQAQLRSKEAENSRLCMQIKNLERSGNQHKAEVEA 364
Query: 135 KLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLV 194
+++L + + LK A +AQ +E+ A +L H+ LY+
Sbjct: 365 IMEQLKELKQKGDRDKESLKKAIRAQKERAEKSEEYAEQL--------HVQLADKDLYVA 416
Query: 195 TTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHN--SLKPPEKPPERGGDEKQMALLNQRI 252
++ + +Q +G+ + + VL L ++ E E + +L+ +
Sbjct: 417 EALSTLESWRSRYNQVVKEKGDLELEIIVLNDRVTDLVNQQQTLEEKMREDRDSLVERLH 476
Query: 253 SQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRAL 312
Q AE + + K E ERLKAS E+ +Q+ G +D + + +
Sbjct: 477 RQTAEYS-AFKLENERLKASFAPMEDKLNQAHLEVQQLKASVKNYEGMIDNYKSQVMKTR 535
Query: 313 QRAHEQTETVRKCLQTTVA---ELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENF 369
A E + +C + E+ +++ A+R Q + + ++L + L +L E
Sbjct: 536 LEADEVAAQLERCDKENKILKDEMNKEIEAARRQFQSQLADLQQLPDILKITEAKLAECQ 595
Query: 370 EQAQ 373
+Q Q
Sbjct: 596 DQLQ 599
Score = 33.9 bits (74), Expect = 1.1
Identities = 35/146 (23%), Positives = 61/146 (41%), Gaps = 10/146 (6%)
Query: 244 QMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQ------- 296
+M +++I L LKSE++ K + ++ L+E HE A+
Sbjct: 100 KMNRYDKKIDSLMNAVGCLKSEVKMQKGERQMAKRFLEERKEELEEVAHELAETEHENTV 159
Query: 297 LGGELDRTRDEAS-RALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELK 355
L ++R ++E LQ+ H Q E ++CL + + E E AA+ QV + +LK
Sbjct: 160 LRHNIERMKEEKDFTILQKKHLQQE--KECLMSKLVEAEMDGAAAAKQVMALKDTIGKLK 217
Query: 356 NRLHWQMKRLTENFEQAQLRILGLQT 381
+ Q +L + L T
Sbjct: 218 TEKQMTCTDINTLTRQKELLLQKLST 243
>AL359091-16|CAI13499.1| 701|Homo sapiens outer dense fiber of
sperm tails 2 protein.
Length = 701
Score = 53.6 bits (123), Expect = 1e-06
Identities = 34/155 (21%), Positives = 71/155 (45%), Gaps = 2/155 (1%)
Query: 19 QHRETQNKLRE-LEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRT 77
Q + + K+RE + E L T K + + + ++ +A E+ +L+
Sbjct: 519 QQQTLEEKMREDRDSLVERLHRQTAEYSAFKLENERLKASFAPMEDKLNQAHLEVQQLKA 578
Query: 78 LMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQ 137
+K + +Y+ + ++ + +E Q N + +++N EI+ + +FQ +L
Sbjct: 579 SVKNYEGMIDNYKSQVMKTRLEADEVAAQLERCDKENKILKDEMNKEIEAARRQFQSQLA 638
Query: 138 ELAPIPDLLKATQMRLKDAQ-QAQAIAEHNAEQLA 171
+L +PD+LK T+ +L + Q Q Q N + A
Sbjct: 639 DLQQLPDILKITEAKLAECQDQLQGYERKNIDLTA 673
Score = 35.1 bits (77), Expect = 0.46
Identities = 72/364 (19%), Positives = 145/364 (39%), Gaps = 22/364 (6%)
Query: 20 HRETQNKLRELEMK--FEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRT 77
+R ++ LRE K E L L+ +A ++ + L Q + +E++EL
Sbjct: 311 NRTLRDLLREQHCKEDSERLMEQQGALLKRLAEADSEKARLLLLLQ---DKDKEVEELLQ 367
Query: 78 LMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQI-NLEIQ--RVKLKFQE 134
++ + Q + + + + Q N+R+ QI NLE + K + +
Sbjct: 368 EIQCEKAQAKTASELSKSMESMRGHLQAQLRSKEAENSRLCMQIKNLERSGNQHKAEVEA 427
Query: 135 KLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLV 194
+++L + + LK A +AQ +E+ A +L H+ LY+
Sbjct: 428 IMEQLKELKQKGDRDKESLKKAIRAQKERAEKSEEYAEQL--------HVQLADKDLYVA 479
Query: 195 TTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHN--SLKPPEKPPERGGDEKQMALLNQRI 252
++ + +Q +G+ + + VL L ++ E E + +L+ +
Sbjct: 480 EALSTLESWRSRYNQVVKEKGDLELEIIVLNDRVTDLVNQQQTLEEKMREDRDSLVERLH 539
Query: 253 SQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRAL 312
Q AE + + K E ERLKAS E+ +Q+ G +D + + +
Sbjct: 540 RQTAEYS-AFKLENERLKASFAPMEDKLNQAHLEVQQLKASVKNYEGMIDNYKSQVMKTR 598
Query: 313 QRAHEQTETVRKCLQTTVA---ELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENF 369
A E + +C + E+ +++ A+R Q + + ++L + L +L E
Sbjct: 599 LEADEVAAQLERCDKENKILKDEMNKEIEAARRQFQSQLADLQQLPDILKITEAKLAECQ 658
Query: 370 EQAQ 373
+Q Q
Sbjct: 659 DQLQ 662
Score = 33.9 bits (74), Expect = 1.1
Identities = 35/146 (23%), Positives = 61/146 (41%), Gaps = 10/146 (6%)
Query: 244 QMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQ------- 296
+M +++I L LKSE++ K + ++ L+E HE A+
Sbjct: 163 KMNRYDKKIDSLMNAVGCLKSEVKMQKGERQMAKRFLEERKEELEEVAHELAETEHENTV 222
Query: 297 LGGELDRTRDEAS-RALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELK 355
L ++R ++E LQ+ H Q E ++CL + + E E AA+ QV + +LK
Sbjct: 223 LRHNIERMKEEKDFTILQKKHLQQE--KECLMSKLVEAEMDGAAAAKQVMALKDTIGKLK 280
Query: 356 NRLHWQMKRLTENFEQAQLRILGLQT 381
+ Q +L + L T
Sbjct: 281 TEKQMTCTDINTLTRQKELLLQKLST 306
>AF053970-1|AAC08409.1| 610|Homo sapiens outer dense fiber protein
2/2 protein.
Length = 610
Score = 53.6 bits (123), Expect = 1e-06
Identities = 34/155 (21%), Positives = 71/155 (45%), Gaps = 2/155 (1%)
Query: 19 QHRETQNKLRE-LEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRT 77
Q + + K+RE + E L T K + + + ++ +A E+ +L+
Sbjct: 428 QQQTLEEKMREDRDSLVERLHRQTAEYSAFKLENERLKASFAPMEDKLNQAHLEVQQLKA 487
Query: 78 LMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQ 137
+K + +Y+ + ++ + +E Q N + +++N EI+ + +FQ +L
Sbjct: 488 SVKNYEGMIDNYKSQVMKTRLEADEVAAQLERCDKENKILKDEMNKEIEAARRQFQSQLA 547
Query: 138 ELAPIPDLLKATQMRLKDAQ-QAQAIAEHNAEQLA 171
+L +PD+LK T+ +L + Q Q Q N + A
Sbjct: 548 DLQQLPDILKITEAKLAECQDQLQGYERKNIDLTA 582
Score = 35.1 bits (77), Expect = 0.46
Identities = 72/364 (19%), Positives = 145/364 (39%), Gaps = 22/364 (6%)
Query: 20 HRETQNKLRELEMK--FEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRT 77
+R ++ LRE K E L L+ +A ++ + L Q + +E++EL
Sbjct: 220 NRTLRDLLREQHCKEDSERLMEQQGALLKRLAEADSEKARLLLLLQ---DKDKEVEELLQ 276
Query: 78 LMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQI-NLEIQ--RVKLKFQE 134
++ + Q + + + + Q N+R+ QI NLE + K + +
Sbjct: 277 EIQCEKAQAKTASELSKSMESMRGHLQAQLRSKEAENSRLCMQIKNLERSGNQHKAEVEA 336
Query: 135 KLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLV 194
+++L + + LK A +AQ +E+ A +L H+ LY+
Sbjct: 337 IMEQLKELKQKGDRDKESLKKAIRAQKERAEKSEEYAEQL--------HVQLADKDLYVA 388
Query: 195 TTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHN--SLKPPEKPPERGGDEKQMALLNQRI 252
++ + +Q +G+ + + VL L ++ E E + +L+ +
Sbjct: 389 EALSTLESWRSRYNQVVKEKGDLELEIIVLNDRVTDLVNQQQTLEEKMREDRDSLVERLH 448
Query: 253 SQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRAL 312
Q AE + + K E ERLKAS E+ +Q+ G +D + + +
Sbjct: 449 RQTAEYS-AFKLENERLKASFAPMEDKLNQAHLEVQQLKASVKNYEGMIDNYKSQVMKTR 507
Query: 313 QRAHEQTETVRKCLQTTVA---ELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENF 369
A E + +C + E+ +++ A+R Q + + ++L + L +L E
Sbjct: 508 LEADEVAAQLERCDKENKILKDEMNKEIEAARRQFQSQLADLQQLPDILKITEAKLAECQ 567
Query: 370 EQAQ 373
+Q Q
Sbjct: 568 DQLQ 571
Score = 33.9 bits (74), Expect = 1.1
Identities = 35/146 (23%), Positives = 61/146 (41%), Gaps = 10/146 (6%)
Query: 244 QMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQ------- 296
+M +++I L LKSE++ K + ++ L+E HE A+
Sbjct: 72 KMNRYDKKIDSLMNAVGCLKSEVKMQKGERQMAKRFLEERKEELEEVAHELAETEHENTV 131
Query: 297 LGGELDRTRDEAS-RALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELK 355
L ++R ++E LQ+ H Q E ++CL + + E E AA+ QV + +LK
Sbjct: 132 LRHNIERMKEEKDFTILQKKHLQQE--KECLMSKLVEAEMDGAAAAKQVMALKDTIGKLK 189
Query: 356 NRLHWQMKRLTENFEQAQLRILGLQT 381
+ Q +L + L T
Sbjct: 190 TEKQMTCTDINTLTRQKELLLQKLST 215
>AF012549-1|AAB66337.1| 638|Homo sapiens outer dense fiber protein
2 protein.
Length = 638
Score = 53.6 bits (123), Expect = 1e-06
Identities = 34/155 (21%), Positives = 71/155 (45%), Gaps = 2/155 (1%)
Query: 19 QHRETQNKLRE-LEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRT 77
Q + + K+RE + E L T K + + + ++ +A E+ +L+
Sbjct: 456 QQQTLEEKMREDRDSLVERLHRQTAEYSAFKLENERLKASFAPMEDKLNQAHLEVQQLKA 515
Query: 78 LMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQ 137
+K + +Y+ + ++ + +E Q N + +++N EI+ + +FQ +L
Sbjct: 516 SVKNYEGMIDNYKSQVMKTRLEADEVAAQLERCDKENKILKDEMNKEIEAARRQFQSQLA 575
Query: 138 ELAPIPDLLKATQMRLKDAQ-QAQAIAEHNAEQLA 171
+L +PD+LK T+ +L + Q Q Q N + A
Sbjct: 576 DLQQLPDILKITEAKLAECQDQLQGYERKNIDLTA 610
Score = 35.1 bits (77), Expect = 0.46
Identities = 72/364 (19%), Positives = 145/364 (39%), Gaps = 22/364 (6%)
Query: 20 HRETQNKLRELEMK--FEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRT 77
+R ++ LRE K E L L+ +A ++ + L Q + +E++EL
Sbjct: 248 NRTLRDLLREQHCKEDSERLMEQQGALLKRLAEADSEKARLLLLLQ---DKDKEVEELLQ 304
Query: 78 LMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQI-NLEIQ--RVKLKFQE 134
++ + Q + + + + Q N+R+ QI NLE + K + +
Sbjct: 305 EIQCEKAQAKTASELSKSMESMRGHLQAQLRSKEAENSRLCMQIKNLERSGNQHKAEVEA 364
Query: 135 KLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLV 194
+++L + + LK A +AQ +E+ A +L H+ LY+
Sbjct: 365 IMEQLKELKQKGDRDKESLKKAIRAQKERAEKSEEYAEQL--------HVQLADKDLYVA 416
Query: 195 TTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHN--SLKPPEKPPERGGDEKQMALLNQRI 252
++ + +Q +G+ + + VL L ++ E E + +L+ +
Sbjct: 417 EALSTLESWRSRYNQVVKEKGDLELEIIVLNDRVTDLVNQQQTLEEKMREDRDSLVERLH 476
Query: 253 SQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRAL 312
Q AE + + K E ERLKAS E+ +Q+ G +D + + +
Sbjct: 477 RQTAEYS-AFKLENERLKASFAPMEDKLNQAHLEVQQLKASVKNYEGMIDNYKSQVMKTR 535
Query: 313 QRAHEQTETVRKCLQTTVA---ELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENF 369
A E + +C + E+ +++ A+R Q + + ++L + L +L E
Sbjct: 536 LEADEVAAQLERCDKENKILKDEMNKEIEAARRQFQSQLADLQQLPDILKITEAKLAECQ 595
Query: 370 EQAQ 373
+Q Q
Sbjct: 596 DQLQ 599
Score = 33.9 bits (74), Expect = 1.1
Identities = 35/146 (23%), Positives = 61/146 (41%), Gaps = 10/146 (6%)
Query: 244 QMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQ------- 296
+M +++I L LKSE++ K + ++ L+E HE A+
Sbjct: 100 KMNRYDKKIDSLMNAVGCLKSEVKMQKGERQMAKRFLEERKEELEEVAHELAETEHENTV 159
Query: 297 LGGELDRTRDEAS-RALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELK 355
L ++R ++E LQ+ H Q E ++CL + + E E AA+ QV + +LK
Sbjct: 160 LRHNIERMKEEKDFTILQKKHLQQE--KECLMSKLVEAEMDGAAAAKQVMALKDTIGKLK 217
Query: 356 NRLHWQMKRLTENFEQAQLRILGLQT 381
+ Q +L + L T
Sbjct: 218 TEKQMTCTDINTLTRQKELLLQKLST 243
>AY517555-1|AAT44528.1| 941|Homo sapiens hypothetical
rhabdomyosarcoma antigen MU-RMS-40.3 protein.
Length = 941
Score = 52.4 bits (120), Expect = 3e-06
Identities = 65/343 (18%), Positives = 140/343 (40%), Gaps = 17/343 (4%)
Query: 58 VRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRI 117
++ L+ E EEI+ R + Q DY A++L E R +T+I
Sbjct: 110 IKELQARIEELEEEIEAERATRAKTEKQRSDY------ARELEELSERLEEAGGVTSTQI 163
Query: 118 SEQINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEH--NAEQLARELN 175
++N + + LK + L+E + + AT +R K A + E N +++ ++L
Sbjct: 164 --ELNKKREAEFLKLRRDLEEATLQHEAMVAT-LRKKHADSVAELGEQIDNLQRVKQKLE 220
Query: 176 CAREKV-VHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIG--RGNKDQTVHVLLHNSLKPP 232
+ + + I S+ V+ E + + ++ RG ++ L + +
Sbjct: 221 KEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKS 280
Query: 233 EKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMH 292
E G +Q+ +SQL+ + + + E LK + ++ A LQ H
Sbjct: 281 RLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRH 340
Query: 293 ECAQLGGELDRTRD---EASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEK 349
+C L + + ++ E RAL +A+ + R +T + +L ++ +++ +
Sbjct: 341 DCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQ 400
Query: 350 EREELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRRTASS 392
+ EE ++ + L + ++ Q + L V+ A++
Sbjct: 401 DSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAA 443
Score = 41.9 bits (94), Expect = 0.004
Identities = 36/143 (25%), Positives = 68/143 (47%), Gaps = 10/143 (6%)
Query: 227 NSLKPPEKPPERGGDEKQMALLNQRISQ--LAENNISLKSEIERLKASVIRTEESALANE 284
NSL + E+ ++ + +L ++ + L N L+ +++ + S++ E +
Sbjct: 20 NSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLD 79
Query: 285 KRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQV 344
+RL++K E QL +++ DE + LQ + E LQ + ELE ++ A RA
Sbjct: 80 ERLKKKDFEYCQLQSKVE---DEQTLGLQFQKKIKE-----LQARIEELEEEIEAERATR 131
Query: 345 STAEKEREELKNRLHWQMKRLTE 367
+ EK+R + L +RL E
Sbjct: 132 AKTEKQRSDYARELEELSERLEE 154
Score = 41.5 bits (93), Expect = 0.005
Identities = 79/397 (19%), Positives = 162/397 (40%), Gaps = 42/397 (10%)
Query: 27 LRELEMKFEGL-ATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQ 85
L E ++ E + AT S + EQ N++ +KQ + +E E + + + +
Sbjct: 180 LEEATLQHEAMVATLRKKHADSVAELGEQIDNLQRVKQ---KLEKEKSEFKLEIDDLSSS 236
Query: 86 LQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDL 145
++ +++ Q N I ++ E+ K + Q + EL+ +
Sbjct: 237 MESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLS-ELTTQKSRLQTEAGELSRQLEE 295
Query: 146 LKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYL-YSLYLVTTMTLTQEDL 204
++ +L ++QA ++ E N A+ + H + + L+ +++
Sbjct: 296 KESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEG 355
Query: 205 FGQSQSEIGRGNKD--------QTVHVLLHNSLKPPEKP-PERGGD-EKQMALLNQRISQ 254
+ Q + + N + +T + L+ +K +R D E+Q+ +N + +
Sbjct: 356 KAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCAS 415
Query: 255 LAENNISLKSEIERLKASVIRTEESALANEKR-------LQEKMHECAQLGGELDRTRDE 307
L + L+ E+E L V R A A +K+ L E +C + EL+ + E
Sbjct: 416 LEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKE 475
Query: 308 A----------SRALQRAHEQTETVR---KCLQTTVAELERQLAASRAQVSTAEKEREEL 354
+ A + A +Q ETV+ K L+ +A+L Q+A + + EK R+++
Sbjct: 476 SRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQI 535
Query: 355 ---KNRLHWQMKRLTENFEQAQLRILGLQ---TQVQS 385
K + ++ E + +IL +Q TQV+S
Sbjct: 536 ELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKS 572
Score = 35.9 bits (79), Expect = 0.26
Identities = 37/130 (28%), Positives = 60/130 (46%), Gaps = 15/130 (11%)
Query: 241 DEKQMAL-LNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGG 299
DE+ + L ++I +L L+ EIE +A+ +TE+ + L+E + GG
Sbjct: 98 DEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEEAGG 157
Query: 300 ------ELDRTRD----EASRALQRA---HE-QTETVRKCLQTTVAELERQLAASRAQVS 345
EL++ R+ + R L+ A HE T+RK +VAEL Q+ +
Sbjct: 158 VTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVATLRKKHADSVAELGEQIDNLQRVKQ 217
Query: 346 TAEKEREELK 355
EKE+ E K
Sbjct: 218 KLEKEKSEFK 227
Score = 34.7 bits (76), Expect = 0.60
Identities = 72/379 (18%), Positives = 149/379 (39%), Gaps = 23/379 (6%)
Query: 48 KEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVE---EQR 104
K + E + + A + R E+ +L+ +E DQL+ + + +Q + EQ
Sbjct: 459 KTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQI 518
Query: 105 RQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQA--QAI 162
+ + +QI LE ++L +E L + Q+ L + + I
Sbjct: 519 AENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKSEIDRKI 578
Query: 163 AEHNAE--QLARELNCAREKVVHIF-RYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQ 219
AE + E QL R E + + S + E + + ++ N+ Q
Sbjct: 579 AEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANR-Q 637
Query: 220 TVHVLLH-NSLKPPEKPPERGGDE--KQMALLNQRISQLAENNISLKSEIERLKASVIRT 276
L H S++ K + D+ + L ++++ + L++E+E L+A++ +T
Sbjct: 638 AAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQT 697
Query: 277 EESALANEKRL---QEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAEL 333
E + E+ L E++ L T+ + L + + E + + +
Sbjct: 698 ERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKA 757
Query: 334 ERQLAASRAQVSTAEKER------EELKNRLHWQMKRLTENFEQA-QLRILGLQTQVQSL 386
++ + + +KE+ E +K L +K L ++A QL + G + Q+Q L
Sbjct: 758 KKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKL 817
Query: 387 R-RTASSTGDGDGENQECT 404
R + +GE ++ T
Sbjct: 818 ETRIRELEFELEGEQKKNT 836
>AF020091-1|AAB69327.1| 622|Homo sapiens smooth muscle myosin heavy
chain SM1 protein.
Length = 622
Score = 52.4 bits (120), Expect = 3e-06
Identities = 73/367 (19%), Positives = 154/367 (41%), Gaps = 30/367 (8%)
Query: 29 ELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQD 88
ELE + L L+ SK+ + NV L++ R +++E++T ++E D+LQ
Sbjct: 151 ELERTNKMLKAEMEDLVSSKDDVGK---NVHELEKSKRALETQMEEMKTQLEELEDELQA 207
Query: 89 YRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDLLKA 148
L+ + ++ + Q +E+ ++QR +++ +L++ L A
Sbjct: 208 TEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAA 267
Query: 149 TQMRLK-DAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQ 207
+ +L+ D + + A+ + + R+ + + L +++++F
Sbjct: 268 AKKKLEGDLKDLELQADSAIKGREEAIKHVRKLQAQMKDFQREL---EDARASRDEIFAT 324
Query: 208 SQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIE 267
++ + + + L L E+ ++ EK+ L + S L+ N +L+ E
Sbjct: 325 AKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKE-ELAEELASSLSGRN-ALQDEKR 382
Query: 268 RLKASVIRTEE-------SALANEKRLQEKMHECAQLGGELDRTR------DEASRALQR 314
RL+A + + EE + A R+++ + QL EL R + A + L+R
Sbjct: 383 RLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLER 442
Query: 315 A--------HEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLT 366
HE V+ ++T+A LE ++A QV +E++ L + K+L
Sbjct: 443 QNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLK 502
Query: 367 ENFEQAQ 373
E Q +
Sbjct: 503 EILLQVE 509
Score = 41.9 bits (94), Expect = 0.004
Identities = 77/398 (19%), Positives = 161/398 (40%), Gaps = 29/398 (7%)
Query: 22 ETQNKLRELEMKFEGLATHT----NMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRT 77
E + R LE + E + T + L +++ EVN++ALK + + DE
Sbjct: 179 ELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQN- 237
Query: 78 LMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQI-NLEIQRVK-LKFQEK 135
+E+ QLQ +Y + +E++R+Q ++ + +LE+Q +K +E+
Sbjct: 238 --EEKRRQLQRQLHEY---ETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREE 292
Query: 136 -LQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLV 194
++ + + +K Q L+DA+ ++ A++ ++ ++ + L +
Sbjct: 293 AIKHVRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERA 352
Query: 195 TTMT-LTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRIS 253
L +E+L + S + N Q L + E+ E ++ M ++ R+
Sbjct: 353 RKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEE--EQGNMEAMSDRVR 410
Query: 254 QLAENNISLKSEIERLKASVIRTEESALANE---KRLQEKMHEC-AQLGGELDRTRDEAS 309
+ + L +E+ +++ + E + E K L+ K+HE + + T
Sbjct: 411 KATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALE 470
Query: 310 RALQRAHEQTETVRKCLQTTVAEL---ERQLAASRAQVSTAEKEREELKNRLHW------ 360
+ + EQ E + Q L +++L QV K E+ K +
Sbjct: 471 AKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVK 530
Query: 361 QMKRLTENFEQAQLRILGLQTQVQSLRRTASSTGDGDG 398
Q+KR E E+ RI + ++Q A+ + + G
Sbjct: 531 QLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMG 568
Score = 33.5 bits (73), Expect = 1.4
Identities = 28/137 (20%), Positives = 62/137 (45%), Gaps = 6/137 (4%)
Query: 242 EKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGEL 301
EK+ L+ +++ E + K E+ER + E ++++ + + +HE + L
Sbjct: 130 EKETKALS--LARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRAL 187
Query: 302 DRTRDEASRALQRAHEQ---TETVRKCLQTTVAELERQLAAS-RAQVSTAEKEREELKNR 357
+ +E L+ ++ TE + L+ + L+ Q +A+ E++R +L+ +
Sbjct: 188 ETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQ 247
Query: 358 LHWQMKRLTENFEQAQL 374
LH L + +Q L
Sbjct: 248 LHEYETELEDERKQRAL 264
Score = 32.3 bits (70), Expect = 3.2
Identities = 32/157 (20%), Positives = 65/157 (41%), Gaps = 1/157 (0%)
Query: 250 QRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEAS 309
+ + +L + E+E +AS +A NEK+ + + QL +L
Sbjct: 295 KHVRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARK 354
Query: 310 RALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENF 369
+A E E + L A L+ + A+++ E+E EE + + R+ +
Sbjct: 355 QADLEKEELAEELASSLSGRNA-LQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKAT 413
Query: 370 EQAQLRILGLQTQVQSLRRTASSTGDGDGENQECTCK 406
+QA+ L T+ + ++ S+ + +N+E K
Sbjct: 414 QQAEQLSNELATERSTAQKNESARQQLERQNKELRSK 450
Score = 30.7 bits (66), Expect = 9.8
Identities = 67/325 (20%), Positives = 133/325 (40%), Gaps = 18/325 (5%)
Query: 47 SKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQ 106
++ +A E+E +L + EA E +EL K +++D + V E +
Sbjct: 124 AEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEK- 182
Query: 107 XXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDLLKATQMRL-KDAQQAQAIAEH 165
T++ E++ +++ ++ + Q + ++A + + +D Q E
Sbjct: 183 --SKRALETQM-EEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEE 239
Query: 166 NAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQE--DLFGQSQSEIGRGNKDQTVHV 223
QL R+L+ E + R +L L + DL Q+ S I +G ++ HV
Sbjct: 240 KRRQLQRQLH-EYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAI-KGREEAIKHV 297
Query: 224 LLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALAN 283
L+ K +R ++ + A ++ + EN KS L+A +++ +E A
Sbjct: 298 ---RKLQAQMKDFQRELEDAR-ASRDEIFATAKENEKKAKS----LEADLMQLQEDLAAA 349
Query: 284 EKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQ 343
E+ ++ E +L EL + ALQ + E L+ + E + + A +
Sbjct: 350 ERARKQADLEKEELAEELASSL-SGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDR 408
Query: 344 VSTAEKEREELKNRLHWQMKRLTEN 368
V A ++ E+L N L + +N
Sbjct: 409 VRKATQQAEQLSNELATERSTAQKN 433
>AF013570-1|AAB69326.1| 588|Homo sapiens smooth muscle myosin heavy
chain SM2 protein.
Length = 588
Score = 52.4 bits (120), Expect = 3e-06
Identities = 73/367 (19%), Positives = 154/367 (41%), Gaps = 30/367 (8%)
Query: 29 ELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQD 88
ELE + L L+ SK+ + NV L++ R +++E++T ++E D+LQ
Sbjct: 151 ELERTNKMLKAEMEDLVSSKDDVGK---NVHELEKSKRALETQMEEMKTQLEELEDELQA 207
Query: 89 YRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDLLKA 148
L+ + ++ + Q +E+ ++QR +++ +L++ L A
Sbjct: 208 TEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAA 267
Query: 149 TQMRLK-DAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQ 207
+ +L+ D + + A+ + + R+ + + L +++++F
Sbjct: 268 AKKKLEGDLKDLELQADSAIKGREEAIKHVRKLQAQMKDFQREL---EDARASRDEIFAT 324
Query: 208 SQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIE 267
++ + + + L L E+ ++ EK+ L + S L+ N +L+ E
Sbjct: 325 AKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKE-ELAEELASSLSGRN-ALQDEKR 382
Query: 268 RLKASVIRTEE-------SALANEKRLQEKMHECAQLGGELDRTR------DEASRALQR 314
RL+A + + EE + A R+++ + QL EL R + A + L+R
Sbjct: 383 RLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLER 442
Query: 315 A--------HEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLT 366
HE V+ ++T+A LE ++A QV +E++ L + K+L
Sbjct: 443 QNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLK 502
Query: 367 ENFEQAQ 373
E Q +
Sbjct: 503 EILLQVE 509
Score = 41.9 bits (94), Expect = 0.004
Identities = 77/398 (19%), Positives = 161/398 (40%), Gaps = 29/398 (7%)
Query: 22 ETQNKLRELEMKFEGLATHT----NMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRT 77
E + R LE + E + T + L +++ EVN++ALK + + DE
Sbjct: 179 ELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQN- 237
Query: 78 LMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQI-NLEIQRVK-LKFQEK 135
+E+ QLQ +Y + +E++R+Q ++ + +LE+Q +K +E+
Sbjct: 238 --EEKRRQLQRQLHEY---ETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREE 292
Query: 136 -LQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLV 194
++ + + +K Q L+DA+ ++ A++ ++ ++ + L +
Sbjct: 293 AIKHVRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERA 352
Query: 195 TTMT-LTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRIS 253
L +E+L + S + N Q L + E+ E ++ M ++ R+
Sbjct: 353 RKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEE--EQGNMEAMSDRVR 410
Query: 254 QLAENNISLKSEIERLKASVIRTEESALANE---KRLQEKMHEC-AQLGGELDRTRDEAS 309
+ + L +E+ +++ + E + E K L+ K+HE + + T
Sbjct: 411 KATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALE 470
Query: 310 RALQRAHEQTETVRKCLQTTVAEL---ERQLAASRAQVSTAEKEREELKNRLHW------ 360
+ + EQ E + Q L +++L QV K E+ K +
Sbjct: 471 AKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVK 530
Query: 361 QMKRLTENFEQAQLRILGLQTQVQSLRRTASSTGDGDG 398
Q+KR E E+ RI + ++Q A+ + + G
Sbjct: 531 QLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMG 568
Score = 33.5 bits (73), Expect = 1.4
Identities = 28/137 (20%), Positives = 62/137 (45%), Gaps = 6/137 (4%)
Query: 242 EKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGEL 301
EK+ L+ +++ E + K E+ER + E ++++ + + +HE + L
Sbjct: 130 EKETKALS--LARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRAL 187
Query: 302 DRTRDEASRALQRAHEQ---TETVRKCLQTTVAELERQLAAS-RAQVSTAEKEREELKNR 357
+ +E L+ ++ TE + L+ + L+ Q +A+ E++R +L+ +
Sbjct: 188 ETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQ 247
Query: 358 LHWQMKRLTENFEQAQL 374
LH L + +Q L
Sbjct: 248 LHEYETELEDERKQRAL 264
Score = 32.3 bits (70), Expect = 3.2
Identities = 32/157 (20%), Positives = 65/157 (41%), Gaps = 1/157 (0%)
Query: 250 QRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEAS 309
+ + +L + E+E +AS +A NEK+ + + QL +L
Sbjct: 295 KHVRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARK 354
Query: 310 RALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENF 369
+A E E + L A L+ + A+++ E+E EE + + R+ +
Sbjct: 355 QADLEKEELAEELASSLSGRNA-LQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKAT 413
Query: 370 EQAQLRILGLQTQVQSLRRTASSTGDGDGENQECTCK 406
+QA+ L T+ + ++ S+ + +N+E K
Sbjct: 414 QQAEQLSNELATERSTAQKNESARQQLERQNKELRSK 450
Score = 30.7 bits (66), Expect = 9.8
Identities = 67/325 (20%), Positives = 133/325 (40%), Gaps = 18/325 (5%)
Query: 47 SKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQ 106
++ +A E+E +L + EA E +EL K +++D + V E +
Sbjct: 124 AEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEK- 182
Query: 107 XXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDLLKATQMRL-KDAQQAQAIAEH 165
T++ E++ +++ ++ + Q + ++A + + +D Q E
Sbjct: 183 --SKRALETQM-EEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEE 239
Query: 166 NAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQE--DLFGQSQSEIGRGNKDQTVHV 223
QL R+L+ E + R +L L + DL Q+ S I +G ++ HV
Sbjct: 240 KRRQLQRQLH-EYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAI-KGREEAIKHV 297
Query: 224 LLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALAN 283
L+ K +R ++ + A ++ + EN KS L+A +++ +E A
Sbjct: 298 ---RKLQAQMKDFQRELEDAR-ASRDEIFATAKENEKKAKS----LEADLMQLQEDLAAA 349
Query: 284 EKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQ 343
E+ ++ E +L EL + ALQ + E L+ + E + + A +
Sbjct: 350 ERARKQADLEKEELAEELASSL-SGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDR 408
Query: 344 VSTAEKEREELKNRLHWQMKRLTEN 368
V A ++ E+L N L + +N
Sbjct: 409 VRKATQQAEQLSNELATERSTAQKN 433
>U25725-1|AAA86889.1| 1017|Homo sapiens AH antigen protein.
Length = 1017
Score = 52.0 bits (119), Expect = 4e-06
Identities = 44/168 (26%), Positives = 77/168 (45%), Gaps = 7/168 (4%)
Query: 207 QSQSEIGRGNKDQTVHVLLHNSLKP-PEKPPERGGDEKQMALLNQRISQLAENNISLKSE 265
+ Q+EI + +T +L N LK E GD++ M Q + E L++
Sbjct: 146 KEQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEEEHQLRNS 205
Query: 266 IERLKASVIRTEESALANEKRLQEKMHECAQLGG---ELDRTRDEASRALQRAHEQTETV 322
IE+L+A + E+ L ++L+E H L G L+R + A + A + E
Sbjct: 206 IEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVENLERELEIARTNQEHAALEAENS 265
Query: 323 RKCLQTTVAELE---RQLAASRAQVSTAEKEREELKNRLHWQMKRLTE 367
+ ++T A++E + L V T E+E+L N L + +R++E
Sbjct: 266 KGEVETLKAKIEGMTQSLRGLELDVVTIRSEKEDLTNELQKEQERISE 313
Score = 46.0 bits (104), Expect = 2e-04
Identities = 70/324 (21%), Positives = 140/324 (43%), Gaps = 29/324 (8%)
Query: 24 QNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQN 83
Q+ L L+ ++ L + K +F ++VN K+ E + E+ E+ E
Sbjct: 483 QDTLEVLQSSYKNLENELELTKMDK-MSFVEKVNKMTAKET--ELQREMHEMAQKTAELQ 539
Query: 84 DQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIP 143
++L + + QL+ E+ + T + ++ + + ++++++ +
Sbjct: 540 EELSGEKNRLAGELQLLLEEIKSSKDQLKELTLENSELKKSLDCMH---KDQVEKEGKVR 596
Query: 144 DLLKATQMRLKDAQQA-QAIAEHNAEQLARELNCAREKVVHIFRYLYSLYL-VTTMTLTQ 201
+ + Q+RL +A++ QA+ +Q E+ REK+ L S L + + ++
Sbjct: 597 EEIAEYQLRLHEAEKKHQALLLDTNKQYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSK 656
Query: 202 EDLFG------QSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQL 255
E+L Q E+ + D +V N LK K ER + +M LL + QL
Sbjct: 657 EELNNSLKATTQILEELKKTKMDNLKYV---NQLK---KENERA--QGKMKLLIKSCKQL 708
Query: 256 AENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQR- 314
E L+ E+ +L+A+ + + + + K + E E +L L+ EA L +
Sbjct: 709 EEEKEILQKELSQLQAAQEKQKTGTVMDTK-VDELTTEIKELKETLEEKTKEADEYLDKY 767
Query: 315 -----AHEQTETVRKCLQTTVAEL 333
+HE+ E ++ L+T VA L
Sbjct: 768 CSLLISHEKLEKAKEMLETQVAHL 791
Score = 33.9 bits (74), Expect = 1.1
Identities = 56/308 (18%), Positives = 126/308 (40%), Gaps = 24/308 (7%)
Query: 81 EQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQEL- 139
+Q + +D + L+ Q +EQ ++ ++ NLE++ + ++ ++K+Q L
Sbjct: 417 KQKLEKKDEEISRLKNQIQDQEQLVSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQ 476
Query: 140 ---APIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTT 196
A + D L+ Q K+ + + + + ++N K + R ++ + T
Sbjct: 477 SKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTA 536
Query: 197 MTLTQEDLFGQSQSEIG---------RGNKDQTVHVLLHNS-LKPPEKPPERGGDEKQMA 246
QE+L G+ G + +KDQ + L NS LK + EK+
Sbjct: 537 E--LQEELSGEKNRLAGELQLLLEEIKSSKDQLKELTLENSELKKSLDCMHKDQVEKE-- 592
Query: 247 LLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRD 306
+ ++AE + L ++ +A ++ T + + +EK+ + L +
Sbjct: 593 --GKVREEIAEYQLRLHEAEKKHQALLLDTNKQYEVEIQTYREKLTSKEEC---LSSQKL 647
Query: 307 EASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLT 366
E L+ + E+ K + EL++ + V+ +KE E + ++ +K
Sbjct: 648 EID-LLKSSKEELNNSLKATTQILEELKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCK 706
Query: 367 ENFEQAQL 374
+ E+ ++
Sbjct: 707 QLEEEKEI 714
Score = 33.5 bits (73), Expect = 1.4
Identities = 26/123 (21%), Positives = 54/123 (43%), Gaps = 6/123 (4%)
Query: 251 RISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASR 310
R+S E L+ IE+L+ + E+ L ++L+E+ E L +++ E
Sbjct: 9 RLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERDGENDSLKDKVENLERELQM 68
Query: 311 ALQRAH------EQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKR 364
+ + E ++ + L+T + E+ R L + T E+E L ++ + +
Sbjct: 69 SEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQ 128
Query: 365 LTE 367
L+E
Sbjct: 129 LSE 131
Score = 33.5 bits (73), Expect = 1.4
Identities = 35/164 (21%), Positives = 77/164 (46%), Gaps = 9/164 (5%)
Query: 241 DEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGE 300
DEK+ + +++ + N SLK ++E L+ + +EE+ E + + + A++
Sbjct: 34 DEKKQLHIAEKLKERDGENDSLKDKVENLERELQMSEEN---QELVILDAENSKAEV-ET 89
Query: 301 LDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHW 360
L +E +R+L+ T+R + L +Q+ + Q+S +K K++L
Sbjct: 90 LKTQIEEMARSLKVFELDLVTLR----SEKENLTKQIQEKQGQLSELDKLLSSFKSQLEE 145
Query: 361 QMKRLTENFEQAQLRILGLQTQVQSLRRTASSTGDGDGENQECT 404
+ + + E+++ + LQ Q++ L ++ GD E + T
Sbjct: 146 KEQAEIQIKEESKTAVEMLQNQLKELNEAVAAL-CGDQEIMKAT 188
>AB019691-1|BAA78718.1| 3899|Homo sapiens Centrosome- and
Golgi-localized PKN-associated protein (CG-NAP) protein.
Length = 3899
Score = 51.6 bits (118), Expect = 5e-06
Identities = 82/372 (22%), Positives = 163/372 (43%), Gaps = 29/372 (7%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGS-KEQAFEQEVNVR-ALKQCYREAREEIDELR 76
Q E + L + + K E + L K EQ+ V + K+ +E I+EL
Sbjct: 276 QLEEQDHLLEDYQKKKEDFTMQISFLQEKIKVYEMEQDKKVENSNKEEIQEKETIIEELN 335
Query: 77 TLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKL 136
T + E+ + + + K A +L+ E + Q N I + + LE+ K K ++
Sbjct: 336 TKIIEEEKKTLELKDKLTTADKLLGELQEQIVQK---NQEI-KNMKLELTNSKQKERQSS 391
Query: 137 QELAPIPDLLKATQMRL-KDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVT 195
+E+ + ++ Q R KD+Q I + ++ R+L R ++ +Y +V
Sbjct: 392 EEIKQLMGTVEELQKRNHKDSQFETDIVQRMEQETQRKLEQLRAELDE----MYGQQIVQ 447
Query: 196 TMTLTQEDLFGQSQSEIGRGNKDQTVHV-LLHNSLKPPEKPPERGGDEKQMALLNQRISQ 254
+++L Q +++ + +T H + N+L+ +E Q+ L+N I++
Sbjct: 448 M----KQELIRQHMAQM---EEIKTRHKGEMENALRSYSNITV---NEDQIKLMNVAINE 497
Query: 255 LAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRD---EASRA 311
L S+ E+LK + E A +++L++ + E + G++ R R E
Sbjct: 498 LNIKLQDTNSQKEKLKEELGLILEEKCALQRQLEDLVEELSFSRGQIQRARQTIAEQESK 557
Query: 312 LQRAHEQTETVR--KCLQTTVAELERQLAAS-RAQVSTAEKEREELKNRLHWQMKRLTEN 368
L AH+ TV K + +E ++L A+V+ + + E L+ + + R+ E+
Sbjct: 558 LNEAHKSLSTVEDLKAEIVSASESRKELELKHEAEVTNYKIKLEMLEKEKNAVLDRMAES 617
Query: 369 FEQAQLRILGLQ 380
++A+L L Q
Sbjct: 618 -QEAELERLSTQ 628
Score = 41.1 bits (92), Expect = 0.007
Identities = 77/382 (20%), Positives = 146/382 (38%), Gaps = 24/382 (6%)
Query: 17 RCQHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELR 76
R Q E +NKL + +M+ GLA + M ++ +Q V Q +E EID+L
Sbjct: 2235 RLQELEQENKLFKDDMEKLGLAIKESDAMSTQ----DQHVLFGKFAQIIQEKEVEIDQLN 2290
Query: 77 TLMKEQNDQLQ---DYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQ 133
+ + QL+ D +V + +L+ + Q + EI+++ +
Sbjct: 2291 EQVTKLQQQLKITTDNKV-IEEKNELIRDLETQIECLMSDQECVKRNREEEIEQLNEVIE 2349
Query: 134 EKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYL 193
+ QELA I + T M + +H + + E ++V + +
Sbjct: 2350 KLQQELANIG---QKTSMNAHSLSEEADSLKHQLDVVIAEKLALEQQVETANEEMTFMKN 2406
Query: 194 VTTMTLTQEDLFGQSQSEIGRGNKD-QTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRI 252
V T + + Q + R + + + + NS+ + E ++ L +
Sbjct: 2407 VLKETNFKMNQLTQELFSLKRERESVEKIQSIPENSVNVAIDHLSKDKPELEVVLTEDAL 2466
Query: 253 SQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRAL 312
L EN KS E K S+I E E + K E Q ++ +++
Sbjct: 2467 KSL-ENQTYFKSFEENGKGSIINLETRLRQLESTVSAKDLELTQCYKQIKDMQEQGQFET 2525
Query: 313 QRAHEQTETVRKCLQTTVAEL---ERQLAASRA--------QVSTAEKEREELKNRLHWQ 361
+ ++ ++K ++ VA + QL A + Q ++E ER ++N +
Sbjct: 2526 EMLQKKIVNLQKIVEEKVAAALVSQIQLEAVQEYAKFCQDNQTISSEPERTNIQNLNQLR 2585
Query: 362 MKRLTENFEQAQLRILGLQTQV 383
L + LRI L++QV
Sbjct: 2586 EDELGSDISALTLRISELESQV 2607
Score = 30.7 bits (66), Expect = 9.8
Identities = 59/308 (19%), Positives = 130/308 (42%), Gaps = 20/308 (6%)
Query: 100 VEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDA-QQ 158
+EEQ Q +Q++++++ K + +LQEL L K +L A ++
Sbjct: 2200 LEEQLEQFREELENKNEEVQQLHMQLEIQKKESTTRLQELEQENKLFKDDMEKLGLAIKE 2259
Query: 159 AQAIAEHNAEQL-ARELNCAREKVVHIFRYLYSL-YLVTTMTLTQEDLFGQSQSEIGRGN 216
+ A++ + L + +EK V I + + L + +T ++ + ++E+ R
Sbjct: 2260 SDAMSTQDQHVLFGKFAQIIQEKEVEIDQLNEQVTKLQQQLKITTDNKVIEEKNELIRDL 2319
Query: 217 KDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAE----NNISLKSEIERLKAS 272
+ Q ++ + E + + L Q ++ + + N SL E + LK
Sbjct: 2320 ETQIECLMSDQECVKRNREEEIEQLNEVIEKLQQELANIGQKTSMNAHSLSEEADSLKHQ 2379
Query: 273 VIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASR------ALQRAHEQTETVRKCL 326
+ LA E++++ E + L T + ++ +L+R E E ++
Sbjct: 2380 LDVVIAEKLALEQQVETANEEMTFMKNVLKETNFKMNQLTQELFSLKRERESVEKIQSIP 2439
Query: 327 QTTVAELERQLAASR--AQVSTAEKEREELKNRLHWQMKRLTENFEQAQLRILGLQTQVQ 384
+ +V L+ + +V E + L+N+ ++ K EN + + I+ L+T+++
Sbjct: 2440 ENSVNVAIDHLSKDKPELEVVLTEDALKSLENQTYF--KSFEENGKGS---IINLETRLR 2494
Query: 385 SLRRTASS 392
L T S+
Sbjct: 2495 QLESTVSA 2502
>X66397-1|CAA47021.1| 2349|Homo sapiens Tpr protein.
Length = 2349
Score = 51.2 bits (117), Expect = 6e-06
Identities = 78/379 (20%), Positives = 168/379 (44%), Gaps = 25/379 (6%)
Query: 17 RCQHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELR 76
RC+ E QN+L L + E L+ + ++ S ++ + +NV +L + + + ++ LR
Sbjct: 1148 RCEDLEKQNRL--LHDQIEKLS---DKVVASVKEGVQGPLNV-SLSEEGKSQEQILEILR 1201
Query: 77 TLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKL 136
+ +E+ ++ + R + Q + L QR + + + +N E ++V Q
Sbjct: 1202 FIRREK--EIAETRFEVAQVESLRYRQRVELLERELQE--LEDSLNAEREKV----QVTA 1253
Query: 137 QELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTT 196
+ +A +L+K T+ + + + E+L ++L + KV + + L
Sbjct: 1254 KTMAQHEELMKKTET-MNVVMETNKMLREEKERLEQDLQQMQAKVRKLELDILPLQEANA 1312
Query: 197 MTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMA---LLNQRIS 253
L+++ G Q+E +D + L +K P+ K ++ + +RI
Sbjct: 1313 -ELSEKS--GMLQAEKKLLEEDVKRWKARNQHLVSQQKDPDTEEYRKLLSEKEVHTKRIQ 1369
Query: 254 QLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQ 313
QL E LK+EI R AS+ + + ++ L + E + +LD + ++
Sbjct: 1370 QLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKVRTEKETIQKDLDAKIIDIQEKVK 1429
Query: 314 RAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQ-MKRLTENFEQA 372
Q + + + +T EL+ Q + ++A+ + + + Q M+ L E QA
Sbjct: 1430 TI-TQVKKIGRRYKTQYEELKAQ--QDKVMETSAQSSGDHQEQHVSVQEMQELKETLNQA 1486
Query: 373 QLRILGLQTQVQSLRRTAS 391
+ + L++QV++L++T S
Sbjct: 1487 ETKSKSLESQVENLQKTLS 1505
Score = 47.6 bits (108), Expect = 8e-05
Identities = 82/402 (20%), Positives = 160/402 (39%), Gaps = 22/402 (5%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTL 78
QH + + EL+ + + L L G + EQE + + + + EL L
Sbjct: 535 QHLVSYRNIEELQQQNQRLLVALREL-GETREREEQETTSSKITELQLKLESALTELEQL 593
Query: 79 MKEQNDQLQ--DYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKL 136
K + Q+Q D V+ +++ Q ++ + ++L + + +
Sbjct: 594 RKSRQHQMQLVDSIVRQRDMYRILLSQTTGVAIPLHASS--LDDVSLASTPKRPSTSQTV 651
Query: 137 QELAPIPDLLKATQMRLKDA-QQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVT 195
AP+P + + K A +Q Q I E+ ++ A E++ + + L
Sbjct: 652 STPAPVPVIESTEAIEAKAALKQLQEIFENYKKEKAENEKIQNEQLEKLQEQVTDLRSQN 711
Query: 196 TMTLTQEDLFGQSQSEIGRGNKD------QTVHVLLHNSLKPPEKPPERGGDEKQ-MALL 248
T TQ D F + E+ + N + ++H +K + Q +
Sbjct: 712 TKISTQLD-FASKRYEMLQDNVEGYRREITSLHERNQKLTATTQKQEQIINTMTQDLRGA 770
Query: 249 NQRISQLAENNISLKSEIERLKASVIR---TEESALANEKRLQEKMHECAQLGGELDRTR 305
N++++ +LK E E LK S +R ES LA ++ + + G L+R+
Sbjct: 771 NEKLAVAEVRAENLKKEKEMLKLSEVRLSQQRESLLAEQRGQNLLLTNLQTIQGILERSE 830
Query: 306 DEASRALQRAHEQTETVRKCLQTTVA-ELERQLAASR-AQVSTAEKERE-ELKNRLHWQM 362
E + L E+ E L+ + E+E++ +R V + +R+ + + LH
Sbjct: 831 TETKQRLSSQIEKLEHEISHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTETNLHLNT 890
Query: 363 KRLTENFEQ--AQLRILGLQTQVQSLRRTASSTGDGDGENQE 402
K L +N ++ A L+ +VQ +++ TG G N+E
Sbjct: 891 KELLKNAQKEIATLKQHLSNMEVQVASQSSQRTGKGQPSNKE 932
Score = 42.7 bits (96), Expect = 0.002
Identities = 59/334 (17%), Positives = 136/334 (40%), Gaps = 12/334 (3%)
Query: 77 TLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKL 136
T + E+N +L K Q + + R +E + E + +KL
Sbjct: 740 TSLHERNQKLTATTQKQEQIINTMTQDLRGANEKLAVAEVRAENLKKEKEMLKLSEVRLS 799
Query: 137 QELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLY---L 193
Q+ + + + L + Q Q I E + + + L+ EK+ H +L +
Sbjct: 800 QQRESLLAEQRGQNLLLTNLQTIQGILERSETETKQRLSSQIEKLEHEISHLKKKLENEV 859
Query: 194 VTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPP---ERGGDEKQMALLNQ 250
TLT+ +L Q + + + +H+ LK +K ++ ++ + +Q
Sbjct: 860 EQRHTLTR-NLDVQLLDTKRQLDTETNLHLNTKELLKNAQKEIATLKQHLSNMEVQVASQ 918
Query: 251 RISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASR 310
+ + S K +++ L + + +TEE ++RL+ Q + +
Sbjct: 919 SSQRTGKGQPSNKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLEE---- 974
Query: 311 ALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFE 370
+L + + TE VRK ++ + E ++ EKE++EL++ ++ + +
Sbjct: 975 SLNKEKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQDDKRRAIESMEQQLS 1034
Query: 371 QAQLRILGLQTQVQ-SLRRTASSTGDGDGENQEC 403
+ + + +Q +VQ +L+R +++ + ++C
Sbjct: 1035 ELKKTLSSVQNEVQEALQRASTALSNEQQARRDC 1068
Score = 33.1 bits (72), Expect = 1.8
Identities = 80/389 (20%), Positives = 159/389 (40%), Gaps = 29/389 (7%)
Query: 21 RETQNKLRELEMKFEG-LATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLM 79
+E + + +E KF L H + K A + E L + A EE+ +L
Sbjct: 262 KEAKEQQASMEEKFHNELNAHIKLSNLYKSAADDSEAKSNELTR----AVEELHKLLKEA 317
Query: 80 KEQNDQLQDYRVKYLQAQ-QLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQE 138
E N +QD+ ++ Q++ Q+ +E + ++ ++ ++ + +E+L
Sbjct: 318 GEANKAIQDHLLEVEQSKDQMEKEMLEKIGRLEKELENANDLLSATKRKGAILSEEELAA 377
Query: 139 LAP-IPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTM 197
++P + K + +K + A E + L +L R I +YL +
Sbjct: 378 MSPTAAAVAKIVKPGMKLTELYNAYVETQDQLLLEKLENKR-----INKYLDE---IVKE 429
Query: 198 TLTQEDLFGQSQSEIGRGNKD-QTVHVLLHNSLKPPEKPPE-RGGDEKQMALL---NQR- 251
+ + + + E R K ++ V L ++K ++ E KQ ++L N+R
Sbjct: 430 VEAKAPILKRQREEYERAQKAVASLSVKLEQAMKEIQRLQEDTDKANKQSSVLERDNRRM 489
Query: 252 ---ISQLAENNISLKSEIERLKAS-VIRTEESALANEKRLQEKMHECAQLGGELDRTRDE 307
+ L++ L E+E + + VIR EE + A+ E + + ++ + +
Sbjct: 490 EIQVKDLSQQIRVLLMELEEARGNHVIRDEEVSSADISSSSEVISQHLVSYRNIEELQQQ 549
Query: 308 ASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTE 367
R L E ET + Q T + ++ + ++ +A E E+L+ QM+ +
Sbjct: 550 NQRLLVALRELGETREREEQETTSS---KITELQLKLESALTELEQLRKSRQHQMQLVDS 606
Query: 368 NFEQAQL-RILGLQTQVQSLRRTASSTGD 395
Q + RIL QT ++ ASS D
Sbjct: 607 IVRQRDMYRILLSQTTGVAIPLHASSLDD 635
Score = 31.9 bits (69), Expect = 4.3
Identities = 38/182 (20%), Positives = 75/182 (41%), Gaps = 14/182 (7%)
Query: 243 KQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANE--------KRLQEKMHEC 294
K++ + R + K E+E K +IRT E L+ E KRL EK+ E
Sbjct: 97 KELEIAQDRNIAIQSQFTRTKEELEAEKRDLIRTNER-LSQELEYLTEDVKRLNEKLKES 155
Query: 295 AQLGGELDRTRDE---ASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKER 351
GEL DE + +++ ++ E ++ L + L +L ++ +E+
Sbjct: 156 NTTKGELQLKLDELQASDVSVKYREKRLEQEKELLHSQNTWLNTELKTKTDELLALGREK 215
Query: 352 EELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRRTASS--TGDGDGENQECTCKNFF 409
L ++ E + + ++ GL+T + L++ T + + Q+ + + F
Sbjct: 216 GNEILELKCNLENKKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEKF 275
Query: 410 DN 411
N
Sbjct: 276 HN 277
>U69668-1|AAB48030.1| 2363|Homo sapiens Tpr protein.
Length = 2363
Score = 51.2 bits (117), Expect = 6e-06
Identities = 78/379 (20%), Positives = 168/379 (44%), Gaps = 25/379 (6%)
Query: 17 RCQHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELR 76
RC+ E QN+L L + E L+ + ++ S ++ + +NV +L + + + ++ LR
Sbjct: 1148 RCEDLEKQNRL--LHDQIEKLS---DKVVASVKEGVQGPLNV-SLSEEGKSQEQILEILR 1201
Query: 77 TLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKL 136
+ +E+ ++ + R + Q + L QR + + + +N E ++V Q
Sbjct: 1202 FIRREK--EIAETRFEVAQVESLRYRQRVELLERELQE--LQDSLNAEREKV----QVTA 1253
Query: 137 QELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTT 196
+ +A +L+K T+ + + + E+L ++L + KV + + L
Sbjct: 1254 KTMAQHEELMKKTET-MNVVMETNKMLREEKERLEQDLQQMQAKVRKLELDILPLQEANA 1312
Query: 197 MTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMA---LLNQRIS 253
L+++ G Q+E +D + L +K P+ K ++ + +RI
Sbjct: 1313 -ELSEKS--GMLQAEKKLLEEDVKRWKARNQHLVSQQKDPDTEEYRKLLSEKEVHTKRIQ 1369
Query: 254 QLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQ 313
QL E LK+EI R AS+ + + ++ L + E + +LD + ++
Sbjct: 1370 QLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKVRTEKETIQKDLDAKIIDIQEKVK 1429
Query: 314 RAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQ-MKRLTENFEQA 372
Q + + + +T EL+ Q + ++A+ + + + Q M+ L E QA
Sbjct: 1430 TI-TQVKKIGRRYKTQYEELKAQ--QDKVMETSAQSSGDHQEQHVSVQEMQELKETLNQA 1486
Query: 373 QLRILGLQTQVQSLRRTAS 391
+ + L++QV++L++T S
Sbjct: 1487 ETKSKSLESQVENLQKTLS 1505
Score = 47.2 bits (107), Expect = 1e-04
Identities = 82/402 (20%), Positives = 160/402 (39%), Gaps = 22/402 (5%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTL 78
QH + + EL+ + + L L G + EQE + + + + EL L
Sbjct: 535 QHLVSYRNIEELQQQNQRLLVALREL-GETREREEQETTSSKITELQLKLESALTELEQL 593
Query: 79 MKEQNDQLQ--DYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKL 136
K + Q+Q D V+ +++ Q ++ + ++L + + +
Sbjct: 594 RKSRQHQMQLVDSIVRQRDMYRILLSQTTGVAIPLHASS--LDDVSLASTPKRPSTSQTV 651
Query: 137 QELAPIPDLLKATQMRLKDA-QQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVT 195
AP+P + + K A +Q Q I E+ ++ A E++ + + L
Sbjct: 652 STPAPVPVIESTEAIEAKAALKQLQEIFENYKKEKAENEKIQNEQLEKLQEQVTDLRSQN 711
Query: 196 TMTLTQEDLFGQSQSEIGRGNKD------QTVHVLLHNSLKPPEKPPERGGDEKQ-MALL 248
T TQ D F + E+ + N + ++H +K + Q +
Sbjct: 712 TKISTQLD-FASKRYEMLQDNVEGYRREITSLHERNQKLTATTQKQEQIINTMTQDLRGA 770
Query: 249 NQRISQLAENNISLKSEIERLKASVIR---TEESALANEKRLQEKMHECAQLGGELDRTR 305
N++++ +LK E E LK S +R ES LA ++ + + G L+R+
Sbjct: 771 NEKLAVAEIRAENLKKEKEMLKLSEVRLSQQRESLLAEQRGQNLLLTNLQTIQGILERSE 830
Query: 306 DEASRALQRAHEQTETVRKCLQTTVA-ELERQLAASR-AQVSTAEKERE-ELKNRLHWQM 362
E + L E+ E L+ + E+E++ +R V + +R+ + + LH
Sbjct: 831 TETKQRLSSQIEKLEHEISHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTETNLHLNT 890
Query: 363 KRLTENFEQ--AQLRILGLQTQVQSLRRTASSTGDGDGENQE 402
K L +N ++ A L+ +VQ +++ TG G N+E
Sbjct: 891 KELLKNAQKEIATLKRHLSNMEVQVASQSSQRTGKGQPSNKE 932
Score = 44.4 bits (100), Expect = 7e-04
Identities = 60/334 (17%), Positives = 136/334 (40%), Gaps = 12/334 (3%)
Query: 77 TLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKL 136
T + E+N +L K Q + + R +E + E + +KL
Sbjct: 740 TSLHERNQKLTATTQKQEQIINTMTQDLRGANEKLAVAEIRAENLKKEKEMLKLSEVRLS 799
Query: 137 QELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLY---L 193
Q+ + + + L + Q Q I E + + + L+ EK+ H +L +
Sbjct: 800 QQRESLLAEQRGQNLLLTNLQTIQGILERSETETKQRLSSQIEKLEHEISHLKKKLENEV 859
Query: 194 VTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPP---ERGGDEKQMALLNQ 250
TLT+ +L Q + + + +H+ LK +K +R ++ + +Q
Sbjct: 860 EQRHTLTR-NLDVQLLDTKRQLDTETNLHLNTKELLKNAQKEIATLKRHLSNMEVQVASQ 918
Query: 251 RISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASR 310
+ + S K +++ L + + +TEE ++RL+ Q + +
Sbjct: 919 SSQRTGKGQPSNKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLEE---- 974
Query: 311 ALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFE 370
+L + + TE VRK ++ + E ++ EKE++EL++ ++ + +
Sbjct: 975 SLNKEKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQDDKRRAIESMEQQLS 1034
Query: 371 QAQLRILGLQTQVQ-SLRRTASSTGDGDGENQEC 403
+ + + +Q +VQ +L+R +++ + ++C
Sbjct: 1035 ELKKTLSSVQNEVQEALQRASTALSNEQQARRDC 1068
Score = 33.1 bits (72), Expect = 1.8
Identities = 80/389 (20%), Positives = 159/389 (40%), Gaps = 29/389 (7%)
Query: 21 RETQNKLRELEMKFEG-LATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLM 79
+E + + +E KF L H + K A + E L + A EE+ +L
Sbjct: 262 KEAKEQQASMEEKFHNELNAHIKLSNLYKSAADDSEAKSNELTR----AVEELHKLLKEA 317
Query: 80 KEQNDQLQDYRVKYLQAQ-QLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQE 138
E N +QD+ ++ Q++ Q+ +E + ++ ++ ++ + +E+L
Sbjct: 318 GEANKAIQDHLLEVEQSKDQMEKEMLEKIGRLEKELENANDLLSATKRKGAILSEEELAA 377
Query: 139 LAP-IPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTM 197
++P + K + +K + A E + L +L R I +YL +
Sbjct: 378 MSPTAAAVAKIVKPGMKLTELYNAYVETQDQLLLEKLENKR-----INKYLDE---IVKE 429
Query: 198 TLTQEDLFGQSQSEIGRGNKD-QTVHVLLHNSLKPPEKPPE-RGGDEKQMALL---NQR- 251
+ + + + E R K ++ V L ++K ++ E KQ ++L N+R
Sbjct: 430 VEAKAPILKRQREEYERAQKAVASLSVKLEQAMKEIQRLQEDTDKANKQSSVLERDNRRM 489
Query: 252 ---ISQLAENNISLKSEIERLKAS-VIRTEESALANEKRLQEKMHECAQLGGELDRTRDE 307
+ L++ L E+E + + VIR EE + A+ E + + ++ + +
Sbjct: 490 EIQVKDLSQQIRVLLMELEEARGNHVIRDEEVSSADISSSSEVISQHLVSYRNIEELQQQ 549
Query: 308 ASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTE 367
R L E ET + Q T + ++ + ++ +A E E+L+ QM+ +
Sbjct: 550 NQRLLVALRELGETREREEQETTSS---KITELQLKLESALTELEQLRKSRQHQMQLVDS 606
Query: 368 NFEQAQL-RILGLQTQVQSLRRTASSTGD 395
Q + RIL QT ++ ASS D
Sbjct: 607 IVRQRDMYRILLSQTTGVAIPLHASSLDD 635
Score = 31.9 bits (69), Expect = 4.3
Identities = 38/182 (20%), Positives = 75/182 (41%), Gaps = 14/182 (7%)
Query: 243 KQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANE--------KRLQEKMHEC 294
K++ + R + K E+E K +IRT E L+ E KRL EK+ E
Sbjct: 97 KELEIAQDRNIAIQSQFTRTKEELEAEKRDLIRTNER-LSQELEYLTEDVKRLNEKLKES 155
Query: 295 AQLGGELDRTRDE---ASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKER 351
GEL DE + +++ ++ E ++ L + L +L ++ +E+
Sbjct: 156 NTTKGELQLKLDELQASDVSVKYREKRLEQEKELLHSQNTWLNTELKTKTDELLALGREK 215
Query: 352 EELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRRTASS--TGDGDGENQECTCKNFF 409
L ++ E + + ++ GL+T + L++ T + + Q+ + + F
Sbjct: 216 GNEILELKCNLENKKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEKF 275
Query: 410 DN 411
N
Sbjct: 276 HN 277
>L09190-1|AAA65582.1| 1898|Homo sapiens trichohyalin protein.
Length = 1898
Score = 51.2 bits (117), Expect = 6e-06
Identities = 72/350 (20%), Positives = 144/350 (41%), Gaps = 28/350 (8%)
Query: 24 QNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQN 83
+ + RE +K E + + + EQE + LK+ E R E L +E+
Sbjct: 458 EQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRE--RWLKLEEEER 515
Query: 84 DQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIP 143
+ Q+ R + L+ +Q EE+R Q R+ +++ E Q+++ + +E+L++L
Sbjct: 516 REQQERREQQLRREQ--EERREQRLKRQEEEERLQQRLRSE-QQLRREQEERLEQL---- 568
Query: 144 DLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQED 203
L + + RL+ ++ Q + E+ + L E+ + L + + +
Sbjct: 569 -LKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVE 627
Query: 204 LFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLK 263
Q + R +++ H LK E+ +E++ L + + E + +
Sbjct: 628 RLEQEERRDERLKREEPEEERRHELLKSEEQ------EERRHEQLRREQQERREQRLKRE 681
Query: 264 SEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVR 323
E ERL+ + R E E+R QE E E ++ R+ + + Q E+
Sbjct: 682 EEEERLEQRLKREHEE----ERREQELAEE------EQEQARERIKSRIPKWQWQLESEA 731
Query: 324 KCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQ 373
Q+ V LE A RA+ ++E+ ++ L WQ + +Q +
Sbjct: 732 DARQSKVL-LEAP-QAGRAEAPQEQEEKRRRESELQWQEEERAHRQQQEE 779
Score = 40.7 bits (91), Expect = 0.009
Identities = 79/378 (20%), Positives = 147/378 (38%), Gaps = 20/378 (5%)
Query: 17 RCQHRETQNKLRELEMKFEGLAT-HTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDEL 75
+ Q E Q + REL+ + E L L +++ +Q+ +R +Q R+ EE E
Sbjct: 259 KLQEEEPQRQ-RELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQ 317
Query: 76 RTLMKEQNDQLQDYRVKYLQAQQLVEEQRR-QXXXXXXXNTRISEQINLEIQRVKLKFQ- 133
+ +EQ ++ + + Q + +E+RR Q R +Q+ E + + + Q
Sbjct: 318 QEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQL 377
Query: 134 EKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYL-YSLY 192
+ QE L+ Q ++ Q + +QL RE RE+ + + L
Sbjct: 378 RREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQ 437
Query: 193 LVTTMTL---TQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLN 249
L L +E+ Q + R + + + LK E+ + ++ L
Sbjct: 438 LRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKR 497
Query: 250 QRISQLAENNISLKSE-----IERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRT 304
+ + E + L+ E ER + + R +E + QE+ Q +
Sbjct: 498 DQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQL 557
Query: 305 RDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKER------EELKNRL 358
R E L++ ++ E R + L+R+ R Q+ E+ER E + RL
Sbjct: 558 RREQEERLEQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERL 617
Query: 359 HWQMKR-LTENFEQAQLR 375
++KR E EQ + R
Sbjct: 618 EQRLKREEVERLEQEERR 635
Score = 39.9 bits (89), Expect = 0.016
Identities = 78/379 (20%), Positives = 150/379 (39%), Gaps = 33/379 (8%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDEL--- 75
+ RE + E +++ E L +++ F +E + ++ R+ REE ++
Sbjct: 1343 EERERKFLKEEQQLRLE----EREQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQ 1398
Query: 76 ---RTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTR-ISEQINLEIQRVKLK 131
R ++E+ Q+ K+ + +QL++E+ Q + + + E+ L Q K
Sbjct: 1399 ERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRK 1458
Query: 132 FQE-KLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYS 190
F+E +L+ P L+ Q + +Q + + E +QL R+ + + ++
Sbjct: 1459 FREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEE--QQLRRQERGQQRRQDRDRKFREE 1516
Query: 191 LYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQ 250
L ++ L Q + R + + E+ R ++Q L Q
Sbjct: 1517 EQL--RQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQ---LRQ 1571
Query: 251 RISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASR 310
+ E+ L E E + + L E +L+ + E QL + DR E +
Sbjct: 1572 EDRKFREDE-QLLQEREEQQLHRQERDRKFLEEEPQLRRQERE-QQLRHDRDRKFREEEQ 1629
Query: 311 ALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENF- 369
LQ EQ Q E +R+ Q+ E+ER+ L+ + + L F
Sbjct: 1630 LLQEGEEQ--------QLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFR 1681
Query: 370 EQAQLRILGLQTQVQSLRR 388
E+ QLR +T+ + LRR
Sbjct: 1682 EEEQLR---QETEQEQLRR 1697
Score = 37.9 bits (84), Expect = 0.065
Identities = 79/365 (21%), Positives = 145/365 (39%), Gaps = 18/365 (4%)
Query: 22 ETQNKLREL-EMKFEGLATHTNMLMGSKEQAF--EQEVNVRALKQCYREAREEIDE---- 74
E Q + REL E++ +G +++ F E+E R + R+ E++ E
Sbjct: 207 EEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQ 266
Query: 75 LRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQE 134
+ ++E+ +QL+ + L+ ++ EEQ++Q R E+ E Q + + QE
Sbjct: 267 RQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQE 326
Query: 135 K--LQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVV---HIFRYLY 189
+ QE L + + R + + + E +QL RE R +
Sbjct: 327 RREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQEEERR 386
Query: 190 SLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLN 249
L L +E + Q ++ R + + L E+ R E+Q+
Sbjct: 387 EQQLRREQQLRREQQLRREQ-QLRREQQLRREQQLRREQQLRREQQLRR---EQQLRREQ 442
Query: 250 QRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQE-KMHECAQLGGELDRTRDEA 308
Q + E K E ER + + R +E KR +E + HE + +L R ++E
Sbjct: 443 QLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEE 502
Query: 309 SRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTEN 368
R E+ E R+ + +L R+ R Q ++E E L+ RL + + E
Sbjct: 503 RRERWLKLEEEER-REQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQ 561
Query: 369 FEQAQ 373
E+ +
Sbjct: 562 EERLE 566
Score = 35.9 bits (79), Expect = 0.26
Identities = 73/362 (20%), Positives = 139/362 (38%), Gaps = 20/362 (5%)
Query: 21 RETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMK 80
RE + L+E E + + ++Q QE + + +Q E R + E + L +
Sbjct: 1420 REEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQ---ELRSQEPERKFLEE 1476
Query: 81 EQNDQLQDYRVKYLQAQQLVEEQRR--QXXXXXXXNTRISEQINLEIQRVKLKFQEKLQE 138
EQ Q + K+LQ +Q + Q R Q R EQ+ E + +L QE+ ++
Sbjct: 1477 EQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRK 1536
Query: 139 LAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMT 198
++ + K + Q + +Q R+ + K + L
Sbjct: 1537 FRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQED---RKFREDEQLLQEREEQQLHR 1593
Query: 199 LTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAEN 258
++ F + + ++ R ++Q + + E+ + G E+Q +R + E
Sbjct: 1594 QERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEG--EEQQLRRQERDRKFREE 1651
Query: 259 NISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDR---TRDEASRALQRA 315
L+ + K EE L ++ L+ K E QL E ++ R E R +
Sbjct: 1652 EQQLRRQERERK---FLQEEQQLRRQE-LERKFREEEQLRQETEQEQLRRQERYRKILE- 1706
Query: 316 HEQTETVRKCLQTTVAELERQLAASRAQVSTAEKE--REELKNRLHWQMKRLTENFEQAQ 373
EQ R+ Q E +R+ E++ R + +R + ++L + E+ Q
Sbjct: 1707 EEQLRPEREEQQLRRQERDRKFREEEQLRQGREEQQLRSQESDRKFREEEQLRQEREEQQ 1766
Query: 374 LR 375
LR
Sbjct: 1767 LR 1768
Score = 35.1 bits (77), Expect = 0.46
Identities = 42/176 (23%), Positives = 72/176 (40%), Gaps = 4/176 (2%)
Query: 229 LKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQ 288
L+ E ER +E+Q L + + + + E + R E+ E++L+
Sbjct: 281 LERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLR 340
Query: 289 EKMHECAQLGGELDRTRDEASRALQRAHEQTETVR-KCLQTTVAELERQLAASRAQVSTA 347
+ E + +L R ++E R Q EQ E R + L+ E R+ R Q
Sbjct: 341 REQEERRE--QQLRREQEEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRR 398
Query: 348 EKE-REELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRRTASSTGDGDGENQE 402
E++ R E + R Q++R + + QLR + Q LRR + + E E
Sbjct: 399 EQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHE 454
Score = 33.5 bits (73), Expect = 1.4
Identities = 35/160 (21%), Positives = 72/160 (45%), Gaps = 9/160 (5%)
Query: 17 RCQHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELR 76
R Q RE Q + + + KF +L +EQ ++ R ++ ++ R + E +
Sbjct: 1608 RRQEREQQLR-HDRDRKFR---EEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERK 1663
Query: 77 TLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRI--SEQINLEIQRVKLKFQE 134
L +EQ + Q+ K+ + +QL +E ++ +I EQ+ E + +L+ QE
Sbjct: 1664 FLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQE 1723
Query: 135 KLQELAPIPDLLKA-TQMRLKDAQQAQAIAEHNAEQLARE 173
+ ++ L + + +L+ + + E EQL +E
Sbjct: 1724 RDRKFREEEQLRQGREEQQLRSQESDRKFREE--EQLRQE 1761
>AL832639-1|CAD89954.1| 1331|Homo sapiens hypothetical protein
protein.
Length = 1331
Score = 51.2 bits (117), Expect = 6e-06
Identities = 67/354 (18%), Positives = 152/354 (42%), Gaps = 27/354 (7%)
Query: 17 RCQHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELR 76
RCQH + + K +++ + L ++++ ++V A ++ EE+D+L
Sbjct: 794 RCQHLQAEKK--KMQQNIQELEEQLEEEESARQKLQLEKVTTEAK---LKKLEEELDDLL 848
Query: 77 TLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRI-SEQINLEIQRVKLK--FQ 133
+ Q + K + QL+ E++ R +E E + + L +
Sbjct: 849 VDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAGERDRAEAEAREKETKALSLARALE 908
Query: 134 EKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLY- 192
E +++ A + L K + ++D ++ + +L + ++V + L L
Sbjct: 909 EAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEG 968
Query: 193 -LVTT------MTLTQEDLFGQSQSEI-GRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQ 244
L T + + + + Q + ++ GR + + L ++ E E ++
Sbjct: 969 ELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRS 1028
Query: 245 MALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRT 304
MA+ ++ +L + L++ I+ S + + A+ ++LQ +M +C + ELD T
Sbjct: 1029 MAVAARK--KLEMDLKDLEAHID----SANKNRDEAIKQLRKLQAQMKDCMR---ELDDT 1079
Query: 305 RDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRL 358
R L +A E + + K ++ + +L+ +LAA+ A++ER+EL + +
Sbjct: 1080 RASREEILAQAKENEKKL-KSMEAEMIQLQEELAAAERAKRQAQQERDELADEI 1132
Score = 46.4 bits (105), Expect = 2e-04
Identities = 81/385 (21%), Positives = 162/385 (42%), Gaps = 42/385 (10%)
Query: 26 KLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQ 85
K+RE ++ E T L + Q +++ ++ Q E E +ELR + + +
Sbjct: 720 KVREKQLAAENRLTEMETL---QSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQE 776
Query: 86 LQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDL 145
L++ L+A+ EE+R Q Q N++ +L+ +E ++ + +
Sbjct: 777 LEEI-CHDLEARVEEEEERCQHLQAEKKKM----QQNIQELEEQLEEEESARQKLQLEKV 831
Query: 146 LKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLF 205
+++ + + + + + + R+ C EK F L L T++ +
Sbjct: 832 TTEAKLKKLEEELDDLLVDLDHQ---RQSACNLEKKQKKFDQL----LAEEKTISAKYAG 884
Query: 206 GQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSE 265
+ ++E + +T + L +L+ E + ++ LN++ E+ +S K +
Sbjct: 885 ERDRAE-AEAREKETKALSLARALE------EAMEQKAELERLNKQFRTEMEDLMSSKDD 937
Query: 266 IERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRD--------------EASRA 311
+ + SV E+S A E++++E + +L GEL T D + R
Sbjct: 938 VGK---SVHELEKSKRALEQQVEEMKTQLEELEGELQATEDAKLRLEVNLQAMKAQFERD 994
Query: 312 LQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELK---NRLHWQMKRLTEN 368
LQ EQ+E +K L V E+E +L R Q S A R++L+ L + +N
Sbjct: 995 LQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKN 1054
Query: 369 FEQAQLRILGLQTQVQSLRRTASST 393
++A ++ LQ Q++ R T
Sbjct: 1055 RDEAIKQLRKLQAQMKDCMRELDDT 1079
Score = 44.0 bits (99), Expect = 0.001
Identities = 67/372 (18%), Positives = 158/372 (42%), Gaps = 38/372 (10%)
Query: 22 ETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKE 81
E + ELE + T LM SK+ + +V L++ R ++++E++T ++E
Sbjct: 909 EAMEQKAELERLNKQFRTEMEDLMSSKDDVGK---SVHELEKSKRALEQQVEEMKTQLEE 965
Query: 82 QNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISE----QINLEIQRVKLKFQEKLQ 137
+LQ L+ + ++ + Q SE Q+ +++ ++ + +++ +
Sbjct: 966 LEGELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERK 1025
Query: 138 ELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTM 197
+ + K +M LKD + A N ++ ++L + ++ R L
Sbjct: 1026 QRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMREL------DDT 1079
Query: 198 TLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAE 257
++E++ Q++ + + + L L E+ + E+ L ++ + +
Sbjct: 1080 RASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERD-ELADEIANSSGK 1138
Query: 258 NNISLKSEIERLKASVIRTEE--------SALANEKRLQEKMHECAQLGGELDRTRDEAS 309
++L+ E RL+A + + EE + L N+ RL++ + Q+ +L+ R A
Sbjct: 1139 GALALE-EKRRLEARIAQLEEELEEEQGNTELIND-RLKKANLQIDQINTDLNLERSHAQ 1196
Query: 310 R------ALQRAHEQTE--------TVRKCLQTTVAELERQLAASRAQVSTAEKEREELK 355
+ L+R +++ + TV+ + ++ LE ++A Q+ KER+
Sbjct: 1197 KNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAAC 1256
Query: 356 NRLHWQMKRLTE 367
++ K+L +
Sbjct: 1257 KQVRRTEKKLKD 1268
>AL596220-1|CAI13119.1| 2363|Homo sapiens translocated promoter region
(to activated MET oncogene) protein.
Length = 2363
Score = 51.2 bits (117), Expect = 6e-06
Identities = 78/379 (20%), Positives = 168/379 (44%), Gaps = 25/379 (6%)
Query: 17 RCQHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELR 76
RC+ E QN+L L + E L+ + ++ S ++ + +NV +L + + + ++ LR
Sbjct: 1148 RCEDLEKQNRL--LHDQIEKLS---DKVVASVKEGVQGPLNV-SLSEEGKSQEQILEILR 1201
Query: 77 TLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKL 136
+ +E+ ++ + R + Q + L QR + + + +N E ++V Q
Sbjct: 1202 FIRREK--EIAETRFEVAQVESLRYRQRVELLERELQE--LQDSLNAEREKV----QVTA 1253
Query: 137 QELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTT 196
+ +A +L+K T+ + + + E+L ++L + KV + + L
Sbjct: 1254 KTMAQHEELMKKTET-MNVVMETNKMLREEKERLEQDLQQMQAKVRKLELDILPLQEANA 1312
Query: 197 MTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMA---LLNQRIS 253
L+++ G Q+E +D + L +K P+ K ++ + +RI
Sbjct: 1313 -ELSEKS--GMLQAEKKLLEEDVKRWKARNQHLVSQQKDPDTEEYRKLLSEKEVHTKRIQ 1369
Query: 254 QLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQ 313
QL E LK+EI R AS+ + + ++ L + E + +LD + ++
Sbjct: 1370 QLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKVRTEKETIQKDLDAKIIDIQEKVK 1429
Query: 314 RAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQ-MKRLTENFEQA 372
Q + + + +T EL+ Q + ++A+ + + + Q M+ L E QA
Sbjct: 1430 TI-TQVKKIGRRYKTQYEELKAQ--QDKVMETSAQSSGDHQEQHVSVQEMQELKETLNQA 1486
Query: 373 QLRILGLQTQVQSLRRTAS 391
+ + L++QV++L++T S
Sbjct: 1487 ETKSKSLESQVENLQKTLS 1505
Score = 47.6 bits (108), Expect = 8e-05
Identities = 82/402 (20%), Positives = 160/402 (39%), Gaps = 22/402 (5%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTL 78
QH + + EL+ + + L L G + EQE + + + + EL L
Sbjct: 535 QHLVSYRNIEELQQQNQRLLVALREL-GETREREEQETTSSKITELQLKLESALTELEQL 593
Query: 79 MKEQNDQLQ--DYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKL 136
K + Q+Q D V+ +++ Q ++ + ++L + + +
Sbjct: 594 RKSRQHQMQLVDSIVRQRDMYRILLSQTTGVAIPLHASS--LDDVSLASTPKRPSTSQTV 651
Query: 137 QELAPIPDLLKATQMRLKDA-QQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVT 195
AP+P + + K A +Q Q I E+ ++ A E++ + + L
Sbjct: 652 STPAPVPVIESTEAIEAKAALKQLQEIFENYKKEKAENEKIQNEQLEKLQEQVTDLRSQN 711
Query: 196 TMTLTQEDLFGQSQSEIGRGNKD------QTVHVLLHNSLKPPEKPPERGGDEKQ-MALL 248
T TQ D F + E+ + N + ++H +K + Q +
Sbjct: 712 TKISTQLD-FASKRYEMLQDNVEGYRREITSLHERNQKLTATTQKQEQIINTMTQDLRGA 770
Query: 249 NQRISQLAENNISLKSEIERLKASVIR---TEESALANEKRLQEKMHECAQLGGELDRTR 305
N++++ +LK E E LK S +R ES LA ++ + + G L+R+
Sbjct: 771 NEKLAVAEVRAENLKKEKEMLKLSEVRLSQQRESLLAEQRGQNLLLTNLQTIQGILERSE 830
Query: 306 DEASRALQRAHEQTETVRKCLQTTVA-ELERQLAASR-AQVSTAEKERE-ELKNRLHWQM 362
E + L E+ E L+ + E+E++ +R V + +R+ + + LH
Sbjct: 831 TETKQRLSSQIEKLEHEISHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTETNLHLNT 890
Query: 363 KRLTENFEQ--AQLRILGLQTQVQSLRRTASSTGDGDGENQE 402
K L +N ++ A L+ +VQ +++ TG G N+E
Sbjct: 891 KELLKNAQKEIATLKQHLSNMEVQVASQSSQRTGKGQPSNKE 932
Score = 42.7 bits (96), Expect = 0.002
Identities = 59/334 (17%), Positives = 136/334 (40%), Gaps = 12/334 (3%)
Query: 77 TLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKL 136
T + E+N +L K Q + + R +E + E + +KL
Sbjct: 740 TSLHERNQKLTATTQKQEQIINTMTQDLRGANEKLAVAEVRAENLKKEKEMLKLSEVRLS 799
Query: 137 QELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLY---L 193
Q+ + + + L + Q Q I E + + + L+ EK+ H +L +
Sbjct: 800 QQRESLLAEQRGQNLLLTNLQTIQGILERSETETKQRLSSQIEKLEHEISHLKKKLENEV 859
Query: 194 VTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPP---ERGGDEKQMALLNQ 250
TLT+ +L Q + + + +H+ LK +K ++ ++ + +Q
Sbjct: 860 EQRHTLTR-NLDVQLLDTKRQLDTETNLHLNTKELLKNAQKEIATLKQHLSNMEVQVASQ 918
Query: 251 RISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASR 310
+ + S K +++ L + + +TEE ++RL+ Q + +
Sbjct: 919 SSQRTGKGQPSNKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLEE---- 974
Query: 311 ALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFE 370
+L + + TE VRK ++ + E ++ EKE++EL++ ++ + +
Sbjct: 975 SLNKEKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQDDKRRAIESMEQQLS 1034
Query: 371 QAQLRILGLQTQVQ-SLRRTASSTGDGDGENQEC 403
+ + + +Q +VQ +L+R +++ + ++C
Sbjct: 1035 ELKKTLSSVQNEVQEALQRASTALSNEQQARRDC 1068
Score = 33.1 bits (72), Expect = 1.8
Identities = 80/389 (20%), Positives = 159/389 (40%), Gaps = 29/389 (7%)
Query: 21 RETQNKLRELEMKFEG-LATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLM 79
+E + + +E KF L H + K A + E L + A EE+ +L
Sbjct: 262 KEAKEQQASMEEKFHNELNAHIKLSNLYKSAADDSEAKSNELTR----AVEELHKLLKEA 317
Query: 80 KEQNDQLQDYRVKYLQAQ-QLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQE 138
E N +QD+ ++ Q++ Q+ +E + ++ ++ ++ + +E+L
Sbjct: 318 GEANKAIQDHLLEVEQSKDQMEKEMLEKIGRLEKELENANDLLSATKRKGAILSEEELAA 377
Query: 139 LAP-IPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTM 197
++P + K + +K + A E + L +L R I +YL +
Sbjct: 378 MSPTAAAVAKIVKPGMKLTELYNAYVETQDQLLLEKLENKR-----INKYLDE---IVKE 429
Query: 198 TLTQEDLFGQSQSEIGRGNKD-QTVHVLLHNSLKPPEKPPE-RGGDEKQMALL---NQR- 251
+ + + + E R K ++ V L ++K ++ E KQ ++L N+R
Sbjct: 430 VEAKAPILKRQREEYERAQKAVASLSVKLEQAMKEIQRLQEDTDKANKQSSVLERDNRRM 489
Query: 252 ---ISQLAENNISLKSEIERLKAS-VIRTEESALANEKRLQEKMHECAQLGGELDRTRDE 307
+ L++ L E+E + + VIR EE + A+ E + + ++ + +
Sbjct: 490 EIQVKDLSQQIRVLLMELEEARGNHVIRDEEVSSADISSSSEVISQHLVSYRNIEELQQQ 549
Query: 308 ASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTE 367
R L E ET + Q T + ++ + ++ +A E E+L+ QM+ +
Sbjct: 550 NQRLLVALRELGETREREEQETTSS---KITELQLKLESALTELEQLRKSRQHQMQLVDS 606
Query: 368 NFEQAQL-RILGLQTQVQSLRRTASSTGD 395
Q + RIL QT ++ ASS D
Sbjct: 607 IVRQRDMYRILLSQTTGVAIPLHASSLDD 635
Score = 31.9 bits (69), Expect = 4.3
Identities = 38/182 (20%), Positives = 75/182 (41%), Gaps = 14/182 (7%)
Query: 243 KQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANE--------KRLQEKMHEC 294
K++ + R + K E+E K +IRT E L+ E KRL EK+ E
Sbjct: 97 KELEIAQDRNIAIQSQFTRTKEELEAEKRDLIRTNER-LSQELEYLTEDVKRLNEKLKES 155
Query: 295 AQLGGELDRTRDE---ASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKER 351
GEL DE + +++ ++ E ++ L + L +L ++ +E+
Sbjct: 156 NTTKGELQLKLDELQASDVSVKYREKRLEQEKELLHSQNTWLNTELKTKTDELLALGREK 215
Query: 352 EELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRRTASS--TGDGDGENQECTCKNFF 409
L ++ E + + ++ GL+T + L++ T + + Q+ + + F
Sbjct: 216 GNEILELKCNLENKKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEKF 275
Query: 410 DN 411
N
Sbjct: 276 HN 277
>AL133553-3|CAI17859.1| 2363|Homo sapiens translocated promoter region
(to activated MET oncogene) protein.
Length = 2363
Score = 51.2 bits (117), Expect = 6e-06
Identities = 78/379 (20%), Positives = 168/379 (44%), Gaps = 25/379 (6%)
Query: 17 RCQHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELR 76
RC+ E QN+L L + E L+ + ++ S ++ + +NV +L + + + ++ LR
Sbjct: 1148 RCEDLEKQNRL--LHDQIEKLS---DKVVASVKEGVQGPLNV-SLSEEGKSQEQILEILR 1201
Query: 77 TLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKL 136
+ +E+ ++ + R + Q + L QR + + + +N E ++V Q
Sbjct: 1202 FIRREK--EIAETRFEVAQVESLRYRQRVELLERELQE--LQDSLNAEREKV----QVTA 1253
Query: 137 QELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTT 196
+ +A +L+K T+ + + + E+L ++L + KV + + L
Sbjct: 1254 KTMAQHEELMKKTET-MNVVMETNKMLREEKERLEQDLQQMQAKVRKLELDILPLQEANA 1312
Query: 197 MTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMA---LLNQRIS 253
L+++ G Q+E +D + L +K P+ K ++ + +RI
Sbjct: 1313 -ELSEKS--GMLQAEKKLLEEDVKRWKARNQHLVSQQKDPDTEEYRKLLSEKEVHTKRIQ 1369
Query: 254 QLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQ 313
QL E LK+EI R AS+ + + ++ L + E + +LD + ++
Sbjct: 1370 QLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKVRTEKETIQKDLDAKIIDIQEKVK 1429
Query: 314 RAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQ-MKRLTENFEQA 372
Q + + + +T EL+ Q + ++A+ + + + Q M+ L E QA
Sbjct: 1430 TI-TQVKKIGRRYKTQYEELKAQ--QDKVMETSAQSSGDHQEQHVSVQEMQELKETLNQA 1486
Query: 373 QLRILGLQTQVQSLRRTAS 391
+ + L++QV++L++T S
Sbjct: 1487 ETKSKSLESQVENLQKTLS 1505
Score = 47.6 bits (108), Expect = 8e-05
Identities = 82/402 (20%), Positives = 160/402 (39%), Gaps = 22/402 (5%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTL 78
QH + + EL+ + + L L G + EQE + + + + EL L
Sbjct: 535 QHLVSYRNIEELQQQNQRLLVALREL-GETREREEQETTSSKITELQLKLESALTELEQL 593
Query: 79 MKEQNDQLQ--DYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKL 136
K + Q+Q D V+ +++ Q ++ + ++L + + +
Sbjct: 594 RKSRQHQMQLVDSIVRQRDMYRILLSQTTGVAIPLHASS--LDDVSLASTPKRPSTSQTV 651
Query: 137 QELAPIPDLLKATQMRLKDA-QQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVT 195
AP+P + + K A +Q Q I E+ ++ A E++ + + L
Sbjct: 652 STPAPVPVIESTEAIEAKAALKQLQEIFENYKKEKAENEKIQNEQLEKLQEQVTDLRSQN 711
Query: 196 TMTLTQEDLFGQSQSEIGRGNKD------QTVHVLLHNSLKPPEKPPERGGDEKQ-MALL 248
T TQ D F + E+ + N + ++H +K + Q +
Sbjct: 712 TKISTQLD-FASKRYEMLQDNVEGYRREITSLHERNQKLTATTQKQEQIINTMTQDLRGA 770
Query: 249 NQRISQLAENNISLKSEIERLKASVIR---TEESALANEKRLQEKMHECAQLGGELDRTR 305
N++++ +LK E E LK S +R ES LA ++ + + G L+R+
Sbjct: 771 NEKLAVAEVRAENLKKEKEMLKLSEVRLSQQRESLLAEQRGQNLLLTNLQTIQGILERSE 830
Query: 306 DEASRALQRAHEQTETVRKCLQTTVA-ELERQLAASR-AQVSTAEKERE-ELKNRLHWQM 362
E + L E+ E L+ + E+E++ +R V + +R+ + + LH
Sbjct: 831 TETKQRLSSQIEKLEHEISHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTETNLHLNT 890
Query: 363 KRLTENFEQ--AQLRILGLQTQVQSLRRTASSTGDGDGENQE 402
K L +N ++ A L+ +VQ +++ TG G N+E
Sbjct: 891 KELLKNAQKEIATLKQHLSNMEVQVASQSSQRTGKGQPSNKE 932
Score = 42.7 bits (96), Expect = 0.002
Identities = 59/334 (17%), Positives = 136/334 (40%), Gaps = 12/334 (3%)
Query: 77 TLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKL 136
T + E+N +L K Q + + R +E + E + +KL
Sbjct: 740 TSLHERNQKLTATTQKQEQIINTMTQDLRGANEKLAVAEVRAENLKKEKEMLKLSEVRLS 799
Query: 137 QELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLY---L 193
Q+ + + + L + Q Q I E + + + L+ EK+ H +L +
Sbjct: 800 QQRESLLAEQRGQNLLLTNLQTIQGILERSETETKQRLSSQIEKLEHEISHLKKKLENEV 859
Query: 194 VTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPP---ERGGDEKQMALLNQ 250
TLT+ +L Q + + + +H+ LK +K ++ ++ + +Q
Sbjct: 860 EQRHTLTR-NLDVQLLDTKRQLDTETNLHLNTKELLKNAQKEIATLKQHLSNMEVQVASQ 918
Query: 251 RISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASR 310
+ + S K +++ L + + +TEE ++RL+ Q + +
Sbjct: 919 SSQRTGKGQPSNKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLEE---- 974
Query: 311 ALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFE 370
+L + + TE VRK ++ + E ++ EKE++EL++ ++ + +
Sbjct: 975 SLNKEKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQDDKRRAIESMEQQLS 1034
Query: 371 QAQLRILGLQTQVQ-SLRRTASSTGDGDGENQEC 403
+ + + +Q +VQ +L+R +++ + ++C
Sbjct: 1035 ELKKTLSSVQNEVQEALQRASTALSNEQQARRDC 1068
Score = 33.1 bits (72), Expect = 1.8
Identities = 80/389 (20%), Positives = 159/389 (40%), Gaps = 29/389 (7%)
Query: 21 RETQNKLRELEMKFEG-LATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLM 79
+E + + +E KF L H + K A + E L + A EE+ +L
Sbjct: 262 KEAKEQQASMEEKFHNELNAHIKLSNLYKSAADDSEAKSNELTR----AVEELHKLLKEA 317
Query: 80 KEQNDQLQDYRVKYLQAQ-QLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQE 138
E N +QD+ ++ Q++ Q+ +E + ++ ++ ++ + +E+L
Sbjct: 318 GEANKAIQDHLLEVEQSKDQMEKEMLEKIGRLEKELENANDLLSATKRKGAILSEEELAA 377
Query: 139 LAP-IPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTM 197
++P + K + +K + A E + L +L R I +YL +
Sbjct: 378 MSPTAAAVAKIVKPGMKLTELYNAYVETQDQLLLEKLENKR-----INKYLDE---IVKE 429
Query: 198 TLTQEDLFGQSQSEIGRGNKD-QTVHVLLHNSLKPPEKPPE-RGGDEKQMALL---NQR- 251
+ + + + E R K ++ V L ++K ++ E KQ ++L N+R
Sbjct: 430 VEAKAPILKRQREEYERAQKAVASLSVKLEQAMKEIQRLQEDTDKANKQSSVLERDNRRM 489
Query: 252 ---ISQLAENNISLKSEIERLKAS-VIRTEESALANEKRLQEKMHECAQLGGELDRTRDE 307
+ L++ L E+E + + VIR EE + A+ E + + ++ + +
Sbjct: 490 EIQVKDLSQQIRVLLMELEEARGNHVIRDEEVSSADISSSSEVISQHLVSYRNIEELQQQ 549
Query: 308 ASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTE 367
R L E ET + Q T + ++ + ++ +A E E+L+ QM+ +
Sbjct: 550 NQRLLVALRELGETREREEQETTSS---KITELQLKLESALTELEQLRKSRQHQMQLVDS 606
Query: 368 NFEQAQL-RILGLQTQVQSLRRTASSTGD 395
Q + RIL QT ++ ASS D
Sbjct: 607 IVRQRDMYRILLSQTTGVAIPLHASSLDD 635
Score = 31.9 bits (69), Expect = 4.3
Identities = 38/182 (20%), Positives = 75/182 (41%), Gaps = 14/182 (7%)
Query: 243 KQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANE--------KRLQEKMHEC 294
K++ + R + K E+E K +IRT E L+ E KRL EK+ E
Sbjct: 97 KELEIAQDRNIAIQSQFTRTKEELEAEKRDLIRTNER-LSQELEYLTEDVKRLNEKLKES 155
Query: 295 AQLGGELDRTRDE---ASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKER 351
GEL DE + +++ ++ E ++ L + L +L ++ +E+
Sbjct: 156 NTTKGELQLKLDELQASDVSVKYREKRLEQEKELLHSQNTWLNTELKTKTDELLALGREK 215
Query: 352 EELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRRTASS--TGDGDGENQECTCKNFF 409
L ++ E + + ++ GL+T + L++ T + + Q+ + + F
Sbjct: 216 GNEILELKCNLENKKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEKF 275
Query: 410 DN 411
N
Sbjct: 276 HN 277
>AK027863-1|BAB55415.1| 612|Homo sapiens protein ( Homo sapiens
cDNA FLJ14957 fis, clone PLACE4000009, weakly similar to
MYOSIN HEAVY CHAIN, NONMUSCLE TYPE B. ).
Length = 612
Score = 51.2 bits (117), Expect = 6e-06
Identities = 91/392 (23%), Positives = 164/392 (41%), Gaps = 29/392 (7%)
Query: 17 RCQHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELR 76
R + RE + EL + L G ++ ++E + ALK +E D+
Sbjct: 29 RSEDREKGALIEELLQAKQDLQDLLIAKEGREDLLRKRERELTALKGALKEEVSSHDQEM 88
Query: 77 TLMKEQND-QLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKL--KFQ 133
+KEQ D +LQ R +A + VE NT +Q E+ RVKL +
Sbjct: 89 DKLKEQYDAELQALRESVEEATKNVE------VLASRSNTSEQDQAGTEM-RVKLLQEEN 141
Query: 134 EKLQELAP-IPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLY 192
EKLQ + + + Q +++D + +A A+ ++ E+ E +VH+ +
Sbjct: 142 EKLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQLEEALVHVRKEEKEAV 201
Query: 193 -----LVTTMTLTQEDLFG--QSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQM 245
L + Q +L Q Q ++ K+++ LK E ER K +
Sbjct: 202 SARRALENELEAAQGNLSQTTQEQKQLSEKLKEESEQKEQLRRLKN-EMENERWHLGKTI 260
Query: 246 ALLNQRISQLAE----NNISLKSEIERLKASVIR--TEESALANEKRLQ-EKMHECAQLG 298
L + ++ + E + + L+++++ K R E EK L+ EK A
Sbjct: 261 EKLQKEMADIVEASRTSTLELQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKM 320
Query: 299 GELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAAS---RAQVSTAEKEREELK 355
+ R +E R QRA ++ T R+ L+ T+ +LE +L A + S K+ E+
Sbjct: 321 QDGMRLMEEELRDYQRAQDEALTKRQLLEQTLKDLEYELEAKSHLKDDRSRLVKQMEDKV 380
Query: 356 NRLHWQMKRLTENFEQAQLRILGLQTQVQSLR 387
++L +++ N + RI + Q++ LR
Sbjct: 381 SQLEMELEEERNNSDLLTERISRSREQMEQLR 412
Score = 42.3 bits (95), Expect = 0.003
Identities = 70/385 (18%), Positives = 143/385 (37%), Gaps = 10/385 (2%)
Query: 21 RETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDE-LRTLM 79
R +N+L + L ++ EQ+ +R LK R + + + L
Sbjct: 205 RALENELEAAQGNLSQTTQEQKQLSEKLKEESEQKEQLRRLKNEMENERWHLGKTIEKLQ 264
Query: 80 KEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQEL 139
KE D ++ R L+ Q ++E + + R ++ LE ++ +L + +
Sbjct: 265 KEMADIVEASRTSTLELQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDGM 324
Query: 140 APIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLY-LVTTMT 198
+ + L+ Q +A + + E + L EL R + + V+ +
Sbjct: 325 RLMEEELRDYQRAQDEALTKRQLLEQTLKDLEYELEAKSHLKDDRSRLVKQMEDKVSQLE 384
Query: 199 LTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAEN 258
+ E+ S R ++ + L N L ++ R E L ++ L
Sbjct: 385 MELEEERNNSDLLTERISRSREQMEQLRNELL--QERAARQDLECDKISLERQNKDLKSR 442
Query: 259 NISLKSEIERLKASVIRTEESALAN-EKRLQEKMHECAQL---GGELDRTRDEASRALQR 314
I L+ K ++ E+ +A E RL+ + + A L L+R E +
Sbjct: 443 IIHLEGSYRSSKEGLVVQMEARIAELEDRLESEERDRANLQLSNRRLERKVKELVMQVDD 502
Query: 315 AHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQL 374
H + L + ++RQ+ + ++ E +++L+ L QM + E+ Q QL
Sbjct: 503 EHLSLTDQKDQLSLRLKAMKRQVEEAEEEIDRLESSKKKLQRELEEQMD-MNEHL-QGQL 560
Query: 375 RILGLQTQVQSLRRTASSTGDGDGE 399
+ +++ L D D +
Sbjct: 561 NSMKKDLRLKKLPSKVLDDMDDDDD 585
>U43195-1|AAB02814.1| 1354|Homo sapiens Rho-associated, coiled-coil
containing protein kinase p160ROCK protein.
Length = 1354
Score = 50.0 bits (114), Expect = 1e-05
Identities = 94/396 (23%), Positives = 163/396 (41%), Gaps = 30/396 (7%)
Query: 17 RCQHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELR 76
R H E + +LE L +L SK Q + ++A+ + R R E+
Sbjct: 565 RKSHTEMSKSISQLESLNRELQERNRILENSKSQTDKDYYQLQAILEAERRDRGHDSEMI 624
Query: 77 TLMKEQNDQLQDYRVKYLQAQ-QLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEK 135
++ + LQ+ VK+L+ + VE +R++ N E+ NLEI + K +
Sbjct: 625 GDLQARITSLQE-EVKHLKHNLEKVEGERKE--AQDMLNHSEKEKNNLEID-LNYKLKSL 680
Query: 136 LQELAPIPDLLKATQMRLKDAQQ----AQAIAEHNAEQLARELNCAREKVVHIFRYLYSL 191
Q L + K T+ RL D Q A+++A E+ +E AREK + +
Sbjct: 681 QQRLEQEVNEHKVTKARLTDKHQSIEEAKSVAMCEMEKKLKEEREAREKAENRVVQIEKQ 740
Query: 192 YLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQR 251
+ + L Q Q + E GNK++ + + +L+ ++ K++ L N+
Sbjct: 741 CSMLDVDLKQ----SQQKLEHLTGNKERMEDEVKNLTLQLEQE------SNKRLLLQNEL 790
Query: 252 ISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRA 311
+Q E + +LK +++K + + L KRL E E AQL + R + R
Sbjct: 791 KTQAFEAD-NLKGLEKQMKQEI-----NTLLEAKRLLE--FELAQLTKQY-RGNEGQMRE 841
Query: 312 LQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQ 371
LQ E + +T V EL+ ++ + +E + K L Q+ L E +
Sbjct: 842 LQDQLEAEQYFSTLYKTQVKELKEEIEEKNRENLKKIQELQNEKETLATQLD-LAETKAE 900
Query: 372 AQLRILGLQTQVQSLRRTASSTGDGDGENQECTCKN 407
++ GL + Q T S QE T K+
Sbjct: 901 SEQLARGL-LEEQYFELTQESKKAASRNRQEITDKD 935
Score = 31.5 bits (68), Expect = 5.6
Identities = 30/122 (24%), Positives = 53/122 (43%), Gaps = 6/122 (4%)
Query: 253 SQLAENNIS-LKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRA 311
SQLA +S L+ ++E ++RTE ++ +M + L+R E +R
Sbjct: 533 SQLANEKLSQLQKQLEEAN-DLLRTESDTAVRLRKSHTEMSKSISQLESLNRELQERNRI 591
Query: 312 LQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQ 371
L+ + QT+ LQ + E ER+ R S + + L ++K L N E+
Sbjct: 592 LENSKSQTDKDYYQLQ-AILEAERR---DRGHDSEMIGDLQARITSLQEEVKHLKHNLEK 647
Query: 372 AQ 373
+
Sbjct: 648 VE 649
>BC113114-1|AAI13115.1| 1354|Homo sapiens Rho-associated,
coiled-coil containing protein kinase 1 protein.
Length = 1354
Score = 50.0 bits (114), Expect = 1e-05
Identities = 94/396 (23%), Positives = 163/396 (41%), Gaps = 30/396 (7%)
Query: 17 RCQHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELR 76
R H E + +LE L +L SK Q + ++A+ + R R E+
Sbjct: 565 RKSHTEMSKSISQLESLNRELQERNRILENSKSQTDKDYYQLQAILEAERRDRGHDSEMI 624
Query: 77 TLMKEQNDQLQDYRVKYLQAQ-QLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEK 135
++ + LQ+ VK+L+ + VE +R++ N E+ NLEI + K +
Sbjct: 625 GDLQARITSLQE-EVKHLKHNLEKVEGERKE--AQDMLNHSEKEKNNLEID-LNYKLKSL 680
Query: 136 LQELAPIPDLLKATQMRLKDAQQ----AQAIAEHNAEQLARELNCAREKVVHIFRYLYSL 191
Q L + K T+ RL D Q A+++A E+ +E AREK + +
Sbjct: 681 QQRLEQEVNEHKVTKARLTDKHQSIEEAKSVAMCEMEKKLKEEREAREKAENRVVQIEKQ 740
Query: 192 YLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQR 251
+ + L Q Q + E GNK++ + + +L+ ++ K++ L N+
Sbjct: 741 CSMLDVDLKQ----SQQKLEHLTGNKERMEDEVKNLTLQLEQE------SNKRLLLQNEL 790
Query: 252 ISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRA 311
+Q E + +LK +++K + + L KRL E E AQL + R + R
Sbjct: 791 KTQAFEAD-NLKGLEKQMKQEI-----NTLLEAKRLLE--FELAQLTKQY-RGNEGQMRE 841
Query: 312 LQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQ 371
LQ E + +T V EL+ ++ + +E + K L Q+ L E +
Sbjct: 842 LQDQLEAEQYFSTLYKTQVKELKEEIEEKNRENLKKIQELQNEKETLATQLD-LAETKAE 900
Query: 372 AQLRILGLQTQVQSLRRTASSTGDGDGENQECTCKN 407
++ GL + Q T S QE T K+
Sbjct: 901 SEQLARGL-LEEQYFELTQESKKAASRNRQEITDKD 935
Score = 31.5 bits (68), Expect = 5.6
Identities = 30/122 (24%), Positives = 53/122 (43%), Gaps = 6/122 (4%)
Query: 253 SQLAENNIS-LKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRA 311
SQLA +S L+ ++E ++RTE ++ +M + L+R E +R
Sbjct: 533 SQLANEKLSQLQKQLEEAN-DLLRTESDTAVRLRKSHTEMSKSISQLESLNRELQERNRI 591
Query: 312 LQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQ 371
L+ + QT+ LQ + E ER+ R S + + L ++K L N E+
Sbjct: 592 LENSKSQTDKDYYQLQ-AILEAERR---DRGHDSEMIGDLQARITSLQEEVKHLKHNLEK 647
Query: 372 AQ 373
+
Sbjct: 648 VE 649
>AL133324-2|CAI19310.2| 1983|Homo sapiens myosin, heavy chain 7B,
cardiac muscle, beta protein.
Length = 1983
Score = 50.0 bits (114), Expect = 1e-05
Identities = 76/335 (22%), Positives = 135/335 (40%), Gaps = 31/335 (9%)
Query: 35 EGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYL 94
E LA L G + E + L++ + +E ++L ++ + D L D +
Sbjct: 896 EELAALRAELRGLRGALAAAEAKRQELEETHVSITQEKNDLALQLQAEQDNLADAEER-- 953
Query: 95 QAQQLVEEQRRQXXXXXXXNTRIS--EQINLEIQRVKLKFQEKLQELAPIPDLLKATQMR 152
L++ + + + R+ E++N ++ + K +++ EL D LK T +
Sbjct: 954 -CHLLIKSKVQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTELKKDIDDLKLTLAK 1012
Query: 153 LKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEI 212
+ +QA E+ + L E+ E V + + +L L G Q+E
Sbjct: 1013 AEKEKQA---TENKVKNLTEEMAALDESVARLTKEKKALQEAHQQAL------GDLQAEE 1063
Query: 213 GRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKAS 272
R + + L ++ E E+ EK++ + +R + E ++ L E S
Sbjct: 1064 DRVSALTKAKLRLEQQVEDLECSLEQ---EKKLRMDTERAKRKLEGDLKLTQE------S 1114
Query: 273 VIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAE 332
V + E++L++K E +QL R DE Q Q + K LQ E
Sbjct: 1115 VADAAQDKQQLEEKLKKKDSELSQLSL---RVEDE-----QLLGAQMQKKIKELQARAEE 1166
Query: 333 LERQLAASRAQVSTAEKEREELKNRLHWQMKRLTE 367
LE +L A RA + EK+R E L +RL E
Sbjct: 1167 LEEELEAERAARARVEKQRAEAARELEELSERLEE 1201
Score = 37.9 bits (84), Expect = 0.065
Identities = 84/387 (21%), Positives = 152/387 (39%), Gaps = 34/387 (8%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTL 78
+ + T+NK++ L + L L +KE+ QE + +AL E + + L
Sbjct: 1016 EKQATENKVKNLTEEMAALDESVARL--TKEKKALQEAHQQALGDLQAE-EDRVSALTKA 1072
Query: 79 MKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQE 138
Q++D Q ++L + R + +++++ + + K + +EKL++
Sbjct: 1073 KLRLEQQVEDLECSLEQEKKLRMDTER-AKRKLEGDLKLTQESVADAAQDKQQLEEKLKK 1131
Query: 139 L-APIPDL-LKATQMRLKDAQQAQAIAE--HNAEQLARELNCAREKVVHIFRY-LYSLYL 193
+ + L L+ +L AQ + I E AE+L EL R + + +
Sbjct: 1132 KDSELSQLSLRVEDEQLLGAQMQKKIKELQARAEELEEELEAERAARARVEKQRAEAARE 1191
Query: 194 VTTMTLTQEDLFGQS----------QSEIGRGNKDQTVHVLLHNSLKPP--EKPPERGGD 241
+ ++ E+ G S ++E+GR ++ L H + K E +
Sbjct: 1192 LEELSERLEEAGGASAGQREGCRKREAELGRLRRELEEAALRHEATVAALRRKQAEGAAE 1251
Query: 242 EKQMALLNQRISQLAENNIS-LKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGE 300
+ QR+ Q E S L+ E++ L A+V L K EK+ C +
Sbjct: 1252 LGEQVDSLQRVRQKLEKEKSELRMEVDDLAANV-----ETLTRAKASAEKL--CRTYEDQ 1304
Query: 301 LDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHW 360
L + + LQR T R LQT EL R L +S + + L
Sbjct: 1305 LSEAKIKVEE-LQRQLADASTQRGRLQTESGELSRLLEEKECLISQLSRGKALAAQSLE- 1362
Query: 361 QMKRLTENFEQAQLRILGLQTQVQSLR 387
+++R E +A+ L VQ+LR
Sbjct: 1363 ELRRQLEEESKAK---SALAHAVQALR 1386
Score = 35.5 bits (78), Expect = 0.35
Identities = 73/352 (20%), Positives = 135/352 (38%), Gaps = 31/352 (8%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTL 78
Q + Q+ L + E + L L G ++ E+ + + R ++++ T
Sbjct: 939 QLQAEQDNLADAEERCHLLIKSKVQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTE 998
Query: 79 MKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQE 138
+K+ D L+ K + +Q E + + + E + + + K QE Q+
Sbjct: 999 LKKDIDDLKLTLAKAEKEKQATENKVKNLTEEMAA---LDESV-ARLTKEKKALQEAHQQ 1054
Query: 139 LAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMT 198
+ DL +A + R+ +A+ E E L E + +EK + + L +
Sbjct: 1055 A--LGDL-QAEEDRVSALTKAKLRLEQQVEDL--ECSLEQEKKLRMDTERAKRKLEGDLK 1109
Query: 199 LTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQM-ALLNQRISQLAE 257
LTQE + +Q + Q + L + R DE+ + A + ++I +L
Sbjct: 1110 LTQESVADAAQDK-------QQLEEKLKKKDSELSQLSLRVEDEQLLGAQMQKKIKELQA 1162
Query: 258 NNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGG--------------ELDR 303
L+ E+E +A+ R E+ + L+E + GG EL R
Sbjct: 1163 RAEELEEELEAERAARARVEKQRAEAARELEELSERLEEAGGASAGQREGCRKREAELGR 1222
Query: 304 TRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELK 355
R E A R +R+ AEL Q+ + + EKE+ EL+
Sbjct: 1223 LRRELEEAALRHEATVAALRRKQAEGAAELGEQVDSLQRVRQKLEKEKSELR 1274
Score = 34.7 bits (76), Expect = 0.60
Identities = 67/308 (21%), Positives = 115/308 (37%), Gaps = 25/308 (8%)
Query: 92 KYLQAQQLVEEQRRQXXXXXX---XNTRISEQINLEIQRVKLKFQEKLQELAPIPDLLKA 148
K ++ +EE+RRQ R S + E+ R++ +E L+ L + K
Sbjct: 1494 KQRHLERALEERRRQEEEMQRELEAAQRESRGLGTELFRLRHGHEEALEALETLKRENKN 1553
Query: 149 TQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLY----SLYLVTTMTLTQEDL 204
Q + D +++ + ++L + + I L +L L T TL +
Sbjct: 1554 LQEEISDLTDQVSLSGKSIQELEKTKKALEGEKSEIQAALEEAEGALELEETKTLRIQLE 1613
Query: 205 FGQSQSEIGR--GNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISL 262
Q ++E+ R KD+ L N + E E + R+ + E +++
Sbjct: 1614 LSQVKAEVDRKLAEKDEECANLRRNHQRAVESLQASLDAETRARNEALRLKKKMEGDLN- 1672
Query: 263 KSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETV 322
++E R A A + +Q ++ E Q G RDE R HEQ + +
Sbjct: 1673 --DLELQLGHATRQATEAQAATRLMQAQLKE-EQAG------RDEEQRLAAELHEQAQAL 1723
Query: 323 RKCLQTTVAELERQLAA------SRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQLRI 376
+ AELE AA SR E E N LH Q L ++ + +
Sbjct: 1724 ERRASLLAAELEELRAALEQGERSRRLAEQELLEATERLNLLHSQNTGLLNQKKKLEADL 1783
Query: 377 LGLQTQVQ 384
L +V+
Sbjct: 1784 AQLSGEVE 1791
Score = 31.5 bits (68), Expect = 5.6
Identities = 35/148 (23%), Positives = 65/148 (43%), Gaps = 15/148 (10%)
Query: 24 QNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALK-QCYREAREEIDELRTLMKEQ 82
+ +REL+ + E L G K+Q + E VR L+ + E ++ + L+ + K +
Sbjct: 1836 EQTVRELQARLE--EAEQAALRGGKKQVQKLEAKVRELEAELDAEQKKHAEALKGVRKHE 1893
Query: 83 NDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPI 142
RVK L Q EE R+ + +++ +++ K +F+E Q+
Sbjct: 1894 R------RVKELAYQ--AEEDRKNLARMQD----LVDKLQSKVKSYKRQFEEAEQQANTN 1941
Query: 143 PDLLKATQMRLKDAQQAQAIAEHNAEQL 170
+ Q L DA++ +AE A +L
Sbjct: 1942 LAKYRKAQHELDDAEERADMAETQANKL 1969
>AL132825-6|CAI43047.2| 1983|Homo sapiens myosin, heavy chain 7B,
cardiac muscle, beta protein.
Length = 1983
Score = 50.0 bits (114), Expect = 1e-05
Identities = 76/335 (22%), Positives = 135/335 (40%), Gaps = 31/335 (9%)
Query: 35 EGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYL 94
E LA L G + E + L++ + +E ++L ++ + D L D +
Sbjct: 896 EELAALRAELRGLRGALAAAEAKRQELEETHVSITQEKNDLALQLQAEQDNLADAEER-- 953
Query: 95 QAQQLVEEQRRQXXXXXXXNTRIS--EQINLEIQRVKLKFQEKLQELAPIPDLLKATQMR 152
L++ + + + R+ E++N ++ + K +++ EL D LK T +
Sbjct: 954 -CHLLIKSKVQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTELKKDIDDLKLTLAK 1012
Query: 153 LKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEI 212
+ +QA E+ + L E+ E V + + +L L G Q+E
Sbjct: 1013 AEKEKQA---TENKVKNLTEEMAALDESVARLTKEKKALQEAHQQAL------GDLQAEE 1063
Query: 213 GRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKAS 272
R + + L ++ E E+ EK++ + +R + E ++ L E S
Sbjct: 1064 DRVSALTKAKLRLEQQVEDLECSLEQ---EKKLRMDTERAKRKLEGDLKLTQE------S 1114
Query: 273 VIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAE 332
V + E++L++K E +QL R DE Q Q + K LQ E
Sbjct: 1115 VADAAQDKQQLEEKLKKKDSELSQLSL---RVEDE-----QLLGAQMQKKIKELQARAEE 1166
Query: 333 LERQLAASRAQVSTAEKEREELKNRLHWQMKRLTE 367
LE +L A RA + EK+R E L +RL E
Sbjct: 1167 LEEELEAERAARARVEKQRAEAARELEELSERLEE 1201
Score = 37.9 bits (84), Expect = 0.065
Identities = 84/387 (21%), Positives = 152/387 (39%), Gaps = 34/387 (8%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTL 78
+ + T+NK++ L + L L +KE+ QE + +AL E + + L
Sbjct: 1016 EKQATENKVKNLTEEMAALDESVARL--TKEKKALQEAHQQALGDLQAE-EDRVSALTKA 1072
Query: 79 MKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQE 138
Q++D Q ++L + R + +++++ + + K + +EKL++
Sbjct: 1073 KLRLEQQVEDLECSLEQEKKLRMDTER-AKRKLEGDLKLTQESVADAAQDKQQLEEKLKK 1131
Query: 139 L-APIPDL-LKATQMRLKDAQQAQAIAE--HNAEQLARELNCAREKVVHIFRY-LYSLYL 193
+ + L L+ +L AQ + I E AE+L EL R + + +
Sbjct: 1132 KDSELSQLSLRVEDEQLLGAQMQKKIKELQARAEELEEELEAERAARARVEKQRAEAARE 1191
Query: 194 VTTMTLTQEDLFGQS----------QSEIGRGNKDQTVHVLLHNSLKPP--EKPPERGGD 241
+ ++ E+ G S ++E+GR ++ L H + K E +
Sbjct: 1192 LEELSERLEEAGGASAGQREGCRKREAELGRLRRELEEAALRHEATVAALRRKQAEGAAE 1251
Query: 242 EKQMALLNQRISQLAENNIS-LKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGE 300
+ QR+ Q E S L+ E++ L A+V L K EK+ C +
Sbjct: 1252 LGEQVDSLQRVRQKLEKEKSELRMEVDDLAANV-----ETLTRAKASAEKL--CRTYEDQ 1304
Query: 301 LDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHW 360
L + + LQR T R LQT EL R L +S + + L
Sbjct: 1305 LSEAKIKVEE-LQRQLADASTQRGRLQTESGELSRLLEEKECLISQLSRGKALAAQSLE- 1362
Query: 361 QMKRLTENFEQAQLRILGLQTQVQSLR 387
+++R E +A+ L VQ+LR
Sbjct: 1363 ELRRQLEEESKAK---SALAHAVQALR 1386
Score = 35.5 bits (78), Expect = 0.35
Identities = 73/352 (20%), Positives = 135/352 (38%), Gaps = 31/352 (8%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTL 78
Q + Q+ L + E + L L G ++ E+ + + R ++++ T
Sbjct: 939 QLQAEQDNLADAEERCHLLIKSKVQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTE 998
Query: 79 MKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQE 138
+K+ D L+ K + +Q E + + + E + + + K QE Q+
Sbjct: 999 LKKDIDDLKLTLAKAEKEKQATENKVKNLTEEMAA---LDESV-ARLTKEKKALQEAHQQ 1054
Query: 139 LAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMT 198
+ DL +A + R+ +A+ E E L E + +EK + + L +
Sbjct: 1055 A--LGDL-QAEEDRVSALTKAKLRLEQQVEDL--ECSLEQEKKLRMDTERAKRKLEGDLK 1109
Query: 199 LTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQM-ALLNQRISQLAE 257
LTQE + +Q + Q + L + R DE+ + A + ++I +L
Sbjct: 1110 LTQESVADAAQDK-------QQLEEKLKKKDSELSQLSLRVEDEQLLGAQMQKKIKELQA 1162
Query: 258 NNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGG--------------ELDR 303
L+ E+E +A+ R E+ + L+E + GG EL R
Sbjct: 1163 RAEELEEELEAERAARARVEKQRAEAARELEELSERLEEAGGASAGQREGCRKREAELGR 1222
Query: 304 TRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELK 355
R E A R +R+ AEL Q+ + + EKE+ EL+
Sbjct: 1223 LRRELEEAALRHEATVAALRRKQAEGAAELGEQVDSLQRVRQKLEKEKSELR 1274
Score = 34.7 bits (76), Expect = 0.60
Identities = 67/308 (21%), Positives = 115/308 (37%), Gaps = 25/308 (8%)
Query: 92 KYLQAQQLVEEQRRQXXXXXX---XNTRISEQINLEIQRVKLKFQEKLQELAPIPDLLKA 148
K ++ +EE+RRQ R S + E+ R++ +E L+ L + K
Sbjct: 1494 KQRHLERALEERRRQEEEMQRELEAAQRESRGLGTELFRLRHGHEEALEALETLKRENKN 1553
Query: 149 TQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLY----SLYLVTTMTLTQEDL 204
Q + D +++ + ++L + + I L +L L T TL +
Sbjct: 1554 LQEEISDLTDQVSLSGKSIQELEKTKKALEGEKSEIQAALEEAEGALELEETKTLRIQLE 1613
Query: 205 FGQSQSEIGR--GNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISL 262
Q ++E+ R KD+ L N + E E + R+ + E +++
Sbjct: 1614 LSQVKAEVDRKLAEKDEECANLRRNHQRAVESLQASLDAETRARNEALRLKKKMEGDLN- 1672
Query: 263 KSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETV 322
++E R A A + +Q ++ E Q G RDE R HEQ + +
Sbjct: 1673 --DLELQLGHATRQATEAQAATRLMQAQLKE-EQAG------RDEEQRLAAELHEQAQAL 1723
Query: 323 RKCLQTTVAELERQLAA------SRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQLRI 376
+ AELE AA SR E E N LH Q L ++ + +
Sbjct: 1724 ERRASLLAAELEELRAALEQGERSRRLAEQELLEATERLNLLHSQNTGLLNQKKKLEADL 1783
Query: 377 LGLQTQVQ 384
L +V+
Sbjct: 1784 AQLSGEVE 1791
Score = 31.5 bits (68), Expect = 5.6
Identities = 35/148 (23%), Positives = 65/148 (43%), Gaps = 15/148 (10%)
Query: 24 QNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALK-QCYREAREEIDELRTLMKEQ 82
+ +REL+ + E L G K+Q + E VR L+ + E ++ + L+ + K +
Sbjct: 1836 EQTVRELQARLE--EAEQAALRGGKKQVQKLEAKVRELEAELDAEQKKHAEALKGVRKHE 1893
Query: 83 NDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPI 142
RVK L Q EE R+ + +++ +++ K +F+E Q+
Sbjct: 1894 R------RVKELAYQ--AEEDRKNLARMQD----LVDKLQSKVKSYKRQFEEAEQQANTN 1941
Query: 143 PDLLKATQMRLKDAQQAQAIAEHNAEQL 170
+ Q L DA++ +AE A +L
Sbjct: 1942 LAKYRKAQHELDDAEERADMAETQANKL 1969
>AB208965-1|BAD92202.1| 705|Homo sapiens Rho-associated,
coiled-coil containing protein kinase 1 variant protein.
Length = 705
Score = 50.0 bits (114), Expect = 1e-05
Identities = 94/396 (23%), Positives = 163/396 (41%), Gaps = 30/396 (7%)
Query: 17 RCQHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELR 76
R H E + +LE L +L SK Q + ++A+ + R R E+
Sbjct: 243 RKSHTEMSKSISQLESLNRELQERNRILENSKSQTDKDYYQLQAILEAERRDRGHDSEMI 302
Query: 77 TLMKEQNDQLQDYRVKYLQAQ-QLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEK 135
++ + LQ+ VK+L+ + VE +R++ N E+ NLEI + K +
Sbjct: 303 GDLQARITSLQE-EVKHLKHNLEKVEGERKE--AQDMLNHSEKEKNNLEID-LNYKLKSL 358
Query: 136 LQELAPIPDLLKATQMRLKDAQQ----AQAIAEHNAEQLARELNCAREKVVHIFRYLYSL 191
Q L + K T+ RL D Q A+++A E+ +E AREK + +
Sbjct: 359 QQRLEQEVNEHKVTKARLTDKHQSIEEAKSVAMCEMEKKLKEEREAREKAENRVVQIEKQ 418
Query: 192 YLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQR 251
+ + L Q Q + E GNK++ + + +L+ ++ K++ L N+
Sbjct: 419 CSMLDVDLKQ----SQQKLEHLTGNKERMEDEVKNLTLQLEQE------SNKRLLLQNEL 468
Query: 252 ISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRA 311
+Q E + +LK +++K + + L KRL E E AQL + R + R
Sbjct: 469 KTQAFEAD-NLKGLEKQMKQEI-----NTLLEAKRLLE--FELAQLTKQY-RGNEGQMRE 519
Query: 312 LQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQ 371
LQ E + +T V EL+ ++ + +E + K L Q+ L E +
Sbjct: 520 LQDQLEAEQYFSTLYKTQVKELKEEIEEKNRENLKKIQELQNEKETLATQLD-LAETKAE 578
Query: 372 AQLRILGLQTQVQSLRRTASSTGDGDGENQECTCKN 407
++ GL + Q T S QE T K+
Sbjct: 579 SEQLARGL-LEEQYFELTQESKKAASRNRQEITDKD 613
Score = 31.5 bits (68), Expect = 5.6
Identities = 30/122 (24%), Positives = 53/122 (43%), Gaps = 6/122 (4%)
Query: 253 SQLAENNIS-LKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRA 311
SQLA +S L+ ++E ++RTE ++ +M + L+R E +R
Sbjct: 211 SQLANEKLSQLQKQLEEAN-DLLRTESDTAVRLRKSHTEMSKSISQLESLNRELQERNRI 269
Query: 312 LQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQ 371
L+ + QT+ LQ + E ER+ R S + + L ++K L N E+
Sbjct: 270 LENSKSQTDKDYYQLQ-AILEAERR---DRGHDSEMIGDLQARITSLQEEVKHLKHNLEK 325
Query: 372 AQ 373
+
Sbjct: 326 VE 327
>BX284668-3|CAH70057.1| 1898|Homo sapiens ciliary rootlet
coiled-coil, rootletin protein.
Length = 1898
Score = 49.6 bits (113), Expect = 2e-05
Identities = 74/346 (21%), Positives = 151/346 (43%), Gaps = 20/346 (5%)
Query: 28 RELEMK-FEGLATHTNMLMGS-KEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQ 85
R+L+++ G + L+G+ ++Q + E RAL++ + R++ D ++ +
Sbjct: 412 RQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAHEDAQRE 471
Query: 86 LQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDL 145
+Q R A +L+ ++ + ++++Q E+++ + K Q +EL D
Sbjct: 472 VQRLR----SANELLSREKSNLAH----SLQVAQQQAEELRQEREKLQAAQEELRRQRDR 523
Query: 146 LKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLF 205
L+ Q +DA Q A E+ R+L K + + L + + Q D+
Sbjct: 524 LEEEQ---EDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDML 580
Query: 206 GQSQSEIGRG-NKDQTVHVLLHNSLKPPEKPPERGGDE-KQMALLNQRISQLAENNISLK 263
++E+ K + V L S+ D +++ LN+ ++Q + L
Sbjct: 581 QAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLV 640
Query: 264 SEIERLKASVI---RTEESALANEKRLQEKMHECAQLGGELDRTRDEAS-RALQRAHEQT 319
+++E K+++ R E + QE++ E +L E+ R E S R ++A E
Sbjct: 641 AQLEEEKSALQGRQRQAEQEATVAREEQERLEEL-RLEQEVARQGLEGSLRVAEQAQEAL 699
Query: 320 ETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRL 365
E L+ ++L+ QLA Q+S E+E E+ + Q++ L
Sbjct: 700 EQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARREAQRQVEAL 745
Score = 46.8 bits (106), Expect = 1e-04
Identities = 65/312 (20%), Positives = 131/312 (41%), Gaps = 22/312 (7%)
Query: 92 KYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDLLKATQM 151
++LQ + + +R + R ++ E + ++ + +A + ++
Sbjct: 1394 EFLQELRSAQRERDELRTQTSALNRQLAEMEAERDSATSRARQLQKAVAESEEARRSVDG 1453
Query: 152 RLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLY--------SLYLVTTMTLTQED 203
RL Q A+ E + + RE ++V + R L S ++ M +
Sbjct: 1454 RLSGVQAELALQEESVRRSERERRATLDQVATLERSLQATESELRASQEKISKMKANETK 1513
Query: 204 LFGQSQ--SEIGRGNKDQTVHVLLHNSLKPPEKPPERGG---DEKQMALLNQRIS----Q 254
L G + E+ ++ +TV + L E R G E Q L R+ Q
Sbjct: 1514 LEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLGLSDREAQAQALQDRVDSLQRQ 1573
Query: 255 LAENNI---SLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRA 311
+A++ + +L+ +ERL ++ + EES A +++ AQ L+ TRD+ +
Sbjct: 1574 VADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSASLNSTRDK-NLH 1632
Query: 312 LQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRL-HWQMKRLTENFE 370
LQ+A E R+ LQ + + L+ +R Q S+ ++ + L+ + +++R+ +
Sbjct: 1633 LQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQRVEAEGQ 1692
Query: 371 QAQLRILGLQTQ 382
QLR + Q Q
Sbjct: 1693 LQQLREVLRQRQ 1704
Score = 40.3 bits (90), Expect = 0.012
Identities = 89/421 (21%), Positives = 168/421 (39%), Gaps = 49/421 (11%)
Query: 17 RCQHRETQNKL-RELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDEL 75
R H E +L RE E + L L ++ EQE L + E E +E+
Sbjct: 869 RAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQR--EQE---ELLARLEAEKEELSEEI 923
Query: 76 RTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEK 135
L +E+++ L + QA L E ++ I+LE++R K Q +
Sbjct: 924 AALQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSR 983
Query: 136 LQELAPIPDLLKATQMRLKDAQQAQAIAEH-----NAEQLAREL-----NCARE------ 179
++ + L +++R AQ+ +A A H ++ AR+L +C RE
Sbjct: 984 QEQDRSTVNAL-TSELRDLRAQREEAAAAHAQEVRRLQEQARDLGKQRDSCLREAEELRT 1042
Query: 180 --KVVHIFRYLYSLYLVTTMTLTQEDLFGQS---------QSEIGRGNKDQTVHVLLHNS 228
+++ R L+ +E G+ + +G G K++ +
Sbjct: 1043 QLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEE 1102
Query: 229 LKPPEKPPERGGDEKQMALLN--QRISQLAENNISLKSEIERLKASVIRTEESALANEKR 286
L+ K E ++A + Q+++ L E ++ E L+ + E S L +
Sbjct: 1103 LRSAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRE 1162
Query: 287 LQEKMHECAQLGGELDRTRDEASR-----AL-QRAHEQTETVRKCLQTTVAELERQLAAS 340
LQE + L E R E + AL +RA +++ L+ + + E L
Sbjct: 1163 LQELRRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVM 1222
Query: 341 RAQVSTAEKEREELKNRLHWQMKRLTENFEQA------QL-RILGLQTQVQSLRRTASST 393
R ++ A+++ +E + + +RL + E+A QL GL+ ++++ R A+
Sbjct: 1223 RQELQVAQRKLQEQEGEFRTRERRLLGSLEEARGTEKQQLDHARGLELKLEAARAEAAEL 1282
Query: 394 G 394
G
Sbjct: 1283 G 1283
Score = 39.5 bits (88), Expect = 0.021
Identities = 88/395 (22%), Positives = 164/395 (41%), Gaps = 50/395 (12%)
Query: 21 RETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMK 80
R+ Q + E E E + L G + + QE +VR + RE R +D++ TL +
Sbjct: 1435 RQLQKAVAESE---EARRSVDGRLSGVQAELALQEESVRRSE---RERRATLDQVATLER 1488
Query: 81 EQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINL-EIQRVKLKFQEKLQEL 139
LQ + +Q+ + + + R+ E ++ E + VKL+ Q + E
Sbjct: 1489 S----LQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLE- 1543
Query: 140 APIPDLLKATQMRLKDAQ-QAQAIAEHNAEQLARELNCAREKV----VHIFRYLYSLYLV 194
L+ +++ L D + QAQA+ + + L R++ + K + + R +L V
Sbjct: 1544 ----GELQRSRLGLSDREAQAQALQDR-VDSLQRQVADSEVKAGTLQLTVERLNGALAKV 1598
Query: 195 TTMTLTQED-------LFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMAL 247
D QS + + +D+ +H L +L E +R ++++
Sbjct: 1599 EESEGALRDKVRGLTEALAQSSASLN-STRDKNLH--LQKALTACEH--DRQVLQERLDA 1653
Query: 248 LNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLG-GE------ 300
Q +S+ + + SL +++ L+ V E + E +LQ+ Q GE
Sbjct: 1654 ARQALSEARKQSSSLGEQVQTLRGEVADLELQRVEAEGQLQQLREVLRQRQEGEAAALNT 1713
Query: 301 LDRTRDEASR------ALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKER--- 351
+ + +DE +LQRA Q E ++ ++ + LE+ A R + E+E+
Sbjct: 1714 VQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVEREKLRS 1773
Query: 352 EELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSL 386
E RL + RL A+L + Q Q+Q L
Sbjct: 1774 HEDTVRLSAEKGRLDRTLTGAELELAEAQRQIQQL 1808
Score = 39.5 bits (88), Expect = 0.021
Identities = 72/368 (19%), Positives = 139/368 (37%), Gaps = 18/368 (4%)
Query: 23 TQNKLRELEMKFEGLATHTNMLMGSKEQAFE----QEVNVRALKQCYREAREEIDELRTL 78
T+++LR + K + + L G K + E E L+ R E+ R
Sbjct: 1493 TESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLG 1552
Query: 79 MKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKL-- 136
+ ++ Q Q + + Q+ V + + R++ + +++ + ++K+
Sbjct: 1553 LSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLTVERLNGAL-AKVEESEGALRDKVRG 1611
Query: 137 --QELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLV 194
+ LA L +T+ + Q+A EH+ + L L+ AR+ + + SL
Sbjct: 1612 LTEALAQSSASLNSTRDKNLHLQKALTACEHDRQVLQERLDAARQALSEARKQSSSLG-E 1670
Query: 195 TTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQ 254
TL E + Q G Q VL + + LL +R+
Sbjct: 1671 QVQTLRGEVADLELQRVEAEGQLQQLREVLRQRQEGEAAALNTVQKLQDERRLLQERLGS 1730
Query: 255 LAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQR 314
L L++E ++ S +R E+ +A + L + E +L D R A +
Sbjct: 1731 LQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVERE--KLRSHEDTVRLSAEKG--- 1785
Query: 315 AHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQL 374
+ + + +AE +RQ+ AQV E+ + + Q ++L E +L
Sbjct: 1786 ---RLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDAQQQQLELQQEVERL 1842
Query: 375 RILGLQTQ 382
R QT+
Sbjct: 1843 RSAQAQTE 1850
Score = 37.5 bits (83), Expect = 0.086
Identities = 69/339 (20%), Positives = 140/339 (41%), Gaps = 28/339 (8%)
Query: 75 LRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINL------EIQRV 128
+ + + ++ Q+QD R +Y +Q L+ R+Q + EQ+ +
Sbjct: 405 IHSALHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQA 464
Query: 129 KLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARE---LNCAREKVVHIF 185
Q ++Q L +LL + L + Q +A+ AE+L +E L A+E++
Sbjct: 465 HEDAQREVQRLRSANELLSREKSNLAHSLQ---VAQQQAEELRQEREKLQAAQEELRRQR 521
Query: 186 RYLYSLY--LVTTMTLTQEDL-FGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDE 242
L V + +L Q E G + L+ +R +
Sbjct: 522 DRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQ 581
Query: 243 KQMALLNQRISQLAENNISLKSEIERLKASVIRTEES----ALANEKRLQEKMHECAQLG 298
+ A + + +++ + L+ + +L+A ++S + NE Q+K+ + +L
Sbjct: 582 AEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKL-DLNRLV 640
Query: 299 GELDRTRDEASRALQRAHEQTETVRKCLQTTVAE--LERQLAAS--RAQVSTAEKEREEL 354
+L+ + A + QR EQ TV + Q + E LE+++A + AE+ +E L
Sbjct: 641 AQLEEEK-SALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEAL 699
Query: 355 KNR---LHWQMKRLTENFEQAQLRILGLQTQVQSLRRTA 390
+ + L + +L E Q ++ G + +++ RR A
Sbjct: 700 EQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARREA 738
Score = 35.5 bits (78), Expect = 0.35
Identities = 87/397 (21%), Positives = 155/397 (39%), Gaps = 34/397 (8%)
Query: 17 RCQHRETQNKLRELEMKFEGLATHT---NMLMGS-KEQAFEQEVNVRALKQCYREAREEI 72
R + Q+ L +L E LA N L+ +E+ + R +Q AREE
Sbjct: 609 RAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQ 668
Query: 73 DELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKF 132
+ L L EQ Q A+Q E +Q +++ EQ+ +++ +
Sbjct: 669 ERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGRE 728
Query: 133 QEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLY 192
QE Q ++A + + A++ +A+A+ +A + + RE R L
Sbjct: 729 QELEQARREAQRQVEALE---RAAREKEALAKEHAGLAVQLVAAEREG-----RTLSEE- 779
Query: 193 LVTTMTLTQEDLFGQ--------SQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQ 244
T + L +E L G +Q E R + LL L E G +Q
Sbjct: 780 -ATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALL---LAKETLTGELAGLRQQ 835
Query: 245 MALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRT 304
+ ++ S E + ER + +R E A+E+ LQ E EL+
Sbjct: 836 IIATQEKASLDKELMAQKLVQAEREAQASLR--EQRAAHEEDLQRLQREKEAAWRELEAE 893
Query: 305 RDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQ----VSTAEKEREELKNRLHW 360
R + LQR EQ E + + L+ EL ++AA + + + AE E+++ +
Sbjct: 894 RAQLQSQLQR--EQEELLAR-LEAEKEELSEEIAALQQERDEGLLLAESEKQQALSLKES 950
Query: 361 QMKRLTENFEQAQLRILGLQTQVQSLRRTASSTGDGD 397
+ L+E + + + +++ +R A S + D
Sbjct: 951 EKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQD 987
>BX284668-2|CAH70055.1| 2017|Homo sapiens ciliary rootlet
coiled-coil, rootletin protein.
Length = 2017
Score = 49.6 bits (113), Expect = 2e-05
Identities = 74/346 (21%), Positives = 151/346 (43%), Gaps = 20/346 (5%)
Query: 28 RELEMK-FEGLATHTNMLMGS-KEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQ 85
R+L+++ G + L+G+ ++Q + E RAL++ + R++ D ++ +
Sbjct: 531 RQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAHEDAQRE 590
Query: 86 LQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDL 145
+Q R A +L+ ++ + ++++Q E+++ + K Q +EL D
Sbjct: 591 VQRLR----SANELLSREKSNLAH----SLQVAQQQAEELRQEREKLQAAQEELRRQRDR 642
Query: 146 LKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLF 205
L+ Q +DA Q A E+ R+L K + + L + + Q D+
Sbjct: 643 LEEEQ---EDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDML 699
Query: 206 GQSQSEIGRG-NKDQTVHVLLHNSLKPPEKPPERGGDE-KQMALLNQRISQLAENNISLK 263
++E+ K + V L S+ D +++ LN+ ++Q + L
Sbjct: 700 QAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLV 759
Query: 264 SEIERLKASVI---RTEESALANEKRLQEKMHECAQLGGELDRTRDEAS-RALQRAHEQT 319
+++E K+++ R E + QE++ E +L E+ R E S R ++A E
Sbjct: 760 AQLEEEKSALQGRQRQAEQEATVAREEQERLEEL-RLEQEVARQGLEGSLRVAEQAQEAL 818
Query: 320 ETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRL 365
E L+ ++L+ QLA Q+S E+E E+ + Q++ L
Sbjct: 819 EQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARREAQRQVEAL 864
Score = 46.8 bits (106), Expect = 1e-04
Identities = 65/312 (20%), Positives = 131/312 (41%), Gaps = 22/312 (7%)
Query: 92 KYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDLLKATQM 151
++LQ + + +R + R ++ E + ++ + +A + ++
Sbjct: 1513 EFLQELRSAQRERDELRTQTSALNRQLAEMEAERDSATSRARQLQKAVAESEEARRSVDG 1572
Query: 152 RLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLY--------SLYLVTTMTLTQED 203
RL Q A+ E + + RE ++V + R L S ++ M +
Sbjct: 1573 RLSGVQAELALQEESVRRSERERRATLDQVATLERSLQATESELRASQEKISKMKANETK 1632
Query: 204 LFGQSQ--SEIGRGNKDQTVHVLLHNSLKPPEKPPERGG---DEKQMALLNQRIS----Q 254
L G + E+ ++ +TV + L E R G E Q L R+ Q
Sbjct: 1633 LEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLGLSDREAQAQALQDRVDSLQRQ 1692
Query: 255 LAENNI---SLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRA 311
+A++ + +L+ +ERL ++ + EES A +++ AQ L+ TRD+ +
Sbjct: 1693 VADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSASLNSTRDK-NLH 1751
Query: 312 LQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRL-HWQMKRLTENFE 370
LQ+A E R+ LQ + + L+ +R Q S+ ++ + L+ + +++R+ +
Sbjct: 1752 LQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQRVEAEGQ 1811
Query: 371 QAQLRILGLQTQ 382
QLR + Q Q
Sbjct: 1812 LQQLREVLRQRQ 1823
Score = 40.3 bits (90), Expect = 0.012
Identities = 89/421 (21%), Positives = 168/421 (39%), Gaps = 49/421 (11%)
Query: 17 RCQHRETQNKL-RELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDEL 75
R H E +L RE E + L L ++ EQE L + E E +E+
Sbjct: 988 RAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQR--EQE---ELLARLEAEKEELSEEI 1042
Query: 76 RTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEK 135
L +E+++ L + QA L E ++ I+LE++R K Q +
Sbjct: 1043 AALQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSR 1102
Query: 136 LQELAPIPDLLKATQMRLKDAQQAQAIAEH-----NAEQLAREL-----NCARE------ 179
++ + L +++R AQ+ +A A H ++ AR+L +C RE
Sbjct: 1103 QEQDRSTVNAL-TSELRDLRAQREEAAAAHAQEVRRLQEQARDLGKQRDSCLREAEELRT 1161
Query: 180 --KVVHIFRYLYSLYLVTTMTLTQEDLFGQS---------QSEIGRGNKDQTVHVLLHNS 228
+++ R L+ +E G+ + +G G K++ +
Sbjct: 1162 QLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEE 1221
Query: 229 LKPPEKPPERGGDEKQMALLN--QRISQLAENNISLKSEIERLKASVIRTEESALANEKR 286
L+ K E ++A + Q+++ L E ++ E L+ + E S L +
Sbjct: 1222 LRSAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRE 1281
Query: 287 LQEKMHECAQLGGELDRTRDEASR-----AL-QRAHEQTETVRKCLQTTVAELERQLAAS 340
LQE + L E R E + AL +RA +++ L+ + + E L
Sbjct: 1282 LQELRRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVM 1341
Query: 341 RAQVSTAEKEREELKNRLHWQMKRLTENFEQA------QL-RILGLQTQVQSLRRTASST 393
R ++ A+++ +E + + +RL + E+A QL GL+ ++++ R A+
Sbjct: 1342 RQELQVAQRKLQEQEGEFRTRERRLLGSLEEARGTEKQQLDHARGLELKLEAARAEAAEL 1401
Query: 394 G 394
G
Sbjct: 1402 G 1402
Score = 39.5 bits (88), Expect = 0.021
Identities = 88/395 (22%), Positives = 164/395 (41%), Gaps = 50/395 (12%)
Query: 21 RETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMK 80
R+ Q + E E E + L G + + QE +VR + RE R +D++ TL +
Sbjct: 1554 RQLQKAVAESE---EARRSVDGRLSGVQAELALQEESVRRSE---RERRATLDQVATLER 1607
Query: 81 EQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINL-EIQRVKLKFQEKLQEL 139
LQ + +Q+ + + + R+ E ++ E + VKL+ Q + E
Sbjct: 1608 S----LQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLE- 1662
Query: 140 APIPDLLKATQMRLKDAQ-QAQAIAEHNAEQLARELNCAREKV----VHIFRYLYSLYLV 194
L+ +++ L D + QAQA+ + + L R++ + K + + R +L V
Sbjct: 1663 ----GELQRSRLGLSDREAQAQALQDR-VDSLQRQVADSEVKAGTLQLTVERLNGALAKV 1717
Query: 195 TTMTLTQED-------LFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMAL 247
D QS + + +D+ +H L +L E +R ++++
Sbjct: 1718 EESEGALRDKVRGLTEALAQSSASLN-STRDKNLH--LQKALTACEH--DRQVLQERLDA 1772
Query: 248 LNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLG-GE------ 300
Q +S+ + + SL +++ L+ V E + E +LQ+ Q GE
Sbjct: 1773 ARQALSEARKQSSSLGEQVQTLRGEVADLELQRVEAEGQLQQLREVLRQRQEGEAAALNT 1832
Query: 301 LDRTRDEASR------ALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKER--- 351
+ + +DE +LQRA Q E ++ ++ + LE+ A R + E+E+
Sbjct: 1833 VQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVEREKLRS 1892
Query: 352 EELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSL 386
E RL + RL A+L + Q Q+Q L
Sbjct: 1893 HEDTVRLSAEKGRLDRTLTGAELELAEAQRQIQQL 1927
Score = 39.5 bits (88), Expect = 0.021
Identities = 72/368 (19%), Positives = 139/368 (37%), Gaps = 18/368 (4%)
Query: 23 TQNKLRELEMKFEGLATHTNMLMGSKEQAFE----QEVNVRALKQCYREAREEIDELRTL 78
T+++LR + K + + L G K + E E L+ R E+ R
Sbjct: 1612 TESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLG 1671
Query: 79 MKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKL-- 136
+ ++ Q Q + + Q+ V + + R++ + +++ + ++K+
Sbjct: 1672 LSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLTVERLNGAL-AKVEESEGALRDKVRG 1730
Query: 137 --QELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLV 194
+ LA L +T+ + Q+A EH+ + L L+ AR+ + + SL
Sbjct: 1731 LTEALAQSSASLNSTRDKNLHLQKALTACEHDRQVLQERLDAARQALSEARKQSSSLG-E 1789
Query: 195 TTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQ 254
TL E + Q G Q VL + + LL +R+
Sbjct: 1790 QVQTLRGEVADLELQRVEAEGQLQQLREVLRQRQEGEAAALNTVQKLQDERRLLQERLGS 1849
Query: 255 LAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQR 314
L L++E ++ S +R E+ +A + L + E +L D R A +
Sbjct: 1850 LQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVERE--KLRSHEDTVRLSAEKG--- 1904
Query: 315 AHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQL 374
+ + + +AE +RQ+ AQV E+ + + Q ++L E +L
Sbjct: 1905 ---RLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDAQQQQLELQQEVERL 1961
Query: 375 RILGLQTQ 382
R QT+
Sbjct: 1962 RSAQAQTE 1969
Score = 37.5 bits (83), Expect = 0.086
Identities = 69/339 (20%), Positives = 140/339 (41%), Gaps = 28/339 (8%)
Query: 75 LRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINL------EIQRV 128
+ + + ++ Q+QD R +Y +Q L+ R+Q + EQ+ +
Sbjct: 524 IHSALHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQA 583
Query: 129 KLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARE---LNCAREKVVHIF 185
Q ++Q L +LL + L + Q +A+ AE+L +E L A+E++
Sbjct: 584 HEDAQREVQRLRSANELLSREKSNLAHSLQ---VAQQQAEELRQEREKLQAAQEELRRQR 640
Query: 186 RYLYSLY--LVTTMTLTQEDL-FGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDE 242
L V + +L Q E G + L+ +R +
Sbjct: 641 DRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQ 700
Query: 243 KQMALLNQRISQLAENNISLKSEIERLKASVIRTEES----ALANEKRLQEKMHECAQLG 298
+ A + + +++ + L+ + +L+A ++S + NE Q+K+ + +L
Sbjct: 701 AEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKL-DLNRLV 759
Query: 299 GELDRTRDEASRALQRAHEQTETVRKCLQTTVAE--LERQLAAS--RAQVSTAEKEREEL 354
+L+ + A + QR EQ TV + Q + E LE+++A + AE+ +E L
Sbjct: 760 AQLEEEK-SALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEAL 818
Query: 355 KNR---LHWQMKRLTENFEQAQLRILGLQTQVQSLRRTA 390
+ + L + +L E Q ++ G + +++ RR A
Sbjct: 819 EQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARREA 857
Score = 35.5 bits (78), Expect = 0.35
Identities = 87/397 (21%), Positives = 155/397 (39%), Gaps = 34/397 (8%)
Query: 17 RCQHRETQNKLRELEMKFEGLATHT---NMLMGS-KEQAFEQEVNVRALKQCYREAREEI 72
R + Q+ L +L E LA N L+ +E+ + R +Q AREE
Sbjct: 728 RAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQ 787
Query: 73 DELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKF 132
+ L L EQ Q A+Q E +Q +++ EQ+ +++ +
Sbjct: 788 ERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGRE 847
Query: 133 QEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLY 192
QE Q ++A + + A++ +A+A+ +A + + RE R L
Sbjct: 848 QELEQARREAQRQVEALE---RAAREKEALAKEHAGLAVQLVAAEREG-----RTLSEE- 898
Query: 193 LVTTMTLTQEDLFGQ--------SQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQ 244
T + L +E L G +Q E R + LL L E G +Q
Sbjct: 899 -ATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALL---LAKETLTGELAGLRQQ 954
Query: 245 MALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRT 304
+ ++ S E + ER + +R E A+E+ LQ E EL+
Sbjct: 955 IIATQEKASLDKELMAQKLVQAEREAQASLR--EQRAAHEEDLQRLQREKEAAWRELEAE 1012
Query: 305 RDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQ----VSTAEKEREELKNRLHW 360
R + LQR EQ E + + L+ EL ++AA + + + AE E+++ +
Sbjct: 1013 RAQLQSQLQR--EQEELLAR-LEAEKEELSEEIAALQQERDEGLLLAESEKQQALSLKES 1069
Query: 361 QMKRLTENFEQAQLRILGLQTQVQSLRRTASSTGDGD 397
+ L+E + + + +++ +R A S + D
Sbjct: 1070 EKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQD 1106
>BC126912-1|AAI26913.1| 1132|Homo sapiens CROCC protein protein.
Length = 1132
Score = 49.6 bits (113), Expect = 2e-05
Identities = 74/346 (21%), Positives = 151/346 (43%), Gaps = 20/346 (5%)
Query: 28 RELEMK-FEGLATHTNMLMGS-KEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQ 85
R+L+++ G + L+G+ ++Q + E RAL++ + R++ D ++ +
Sbjct: 394 RQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAHEDAQRE 453
Query: 86 LQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDL 145
+Q R A +L+ ++ + ++++Q E+++ + K Q +EL D
Sbjct: 454 VQRLR----SANELLSREKSNLAH----SLQVAQQQAEELRQEREKLQAAQEELRRQRDR 505
Query: 146 LKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLF 205
L+ Q +DA Q A E+ R+L K + + L + + Q D+
Sbjct: 506 LEEEQ---EDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDML 562
Query: 206 GQSQSEIGRG-NKDQTVHVLLHNSLKPPEKPPERGGDE-KQMALLNQRISQLAENNISLK 263
++E+ K + V L S+ D +++ LN+ ++Q + L
Sbjct: 563 QAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLV 622
Query: 264 SEIERLKASVI---RTEESALANEKRLQEKMHECAQLGGELDRTRDEAS-RALQRAHEQT 319
+++E K+++ R E + QE++ E +L E+ R E S R ++A E
Sbjct: 623 AQLEEEKSALQGRQRQAEQEATVAREEQERLEEL-RLEQEVARQGLEGSLRVAEQAQEAL 681
Query: 320 ETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRL 365
E L+ ++L+ QLA Q+S E+E E+ + Q++ L
Sbjct: 682 EQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARREAQRQVEAL 727
Score = 37.5 bits (83), Expect = 0.086
Identities = 69/339 (20%), Positives = 140/339 (41%), Gaps = 28/339 (8%)
Query: 75 LRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINL------EIQRV 128
+ + + ++ Q+QD R +Y +Q L+ R+Q + EQ+ +
Sbjct: 387 IHSALHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQA 446
Query: 129 KLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARE---LNCAREKVVHIF 185
Q ++Q L +LL + L + Q +A+ AE+L +E L A+E++
Sbjct: 447 HEDAQREVQRLRSANELLSREKSNLAHSLQ---VAQQQAEELRQEREKLQAAQEELRRQR 503
Query: 186 RYLYSLY--LVTTMTLTQEDL-FGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDE 242
L V + +L Q E G + L+ +R +
Sbjct: 504 DRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQ 563
Query: 243 KQMALLNQRISQLAENNISLKSEIERLKASVIRTEES----ALANEKRLQEKMHECAQLG 298
+ A + + +++ + L+ + +L+A ++S + NE Q+K+ + +L
Sbjct: 564 AEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKL-DLNRLV 622
Query: 299 GELDRTRDEASRALQRAHEQTETVRKCLQTTVAE--LERQLAAS--RAQVSTAEKEREEL 354
+L+ + A + QR EQ TV + Q + E LE+++A + AE+ +E L
Sbjct: 623 AQLEEEK-SALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEAL 681
Query: 355 KNR---LHWQMKRLTENFEQAQLRILGLQTQVQSLRRTA 390
+ + L + +L E Q ++ G + +++ RR A
Sbjct: 682 EQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARREA 720
Score = 35.5 bits (78), Expect = 0.35
Identities = 87/397 (21%), Positives = 155/397 (39%), Gaps = 34/397 (8%)
Query: 17 RCQHRETQNKLRELEMKFEGLATHT---NMLMGS-KEQAFEQEVNVRALKQCYREAREEI 72
R + Q+ L +L E LA N L+ +E+ + R +Q AREE
Sbjct: 591 RAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQ 650
Query: 73 DELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKF 132
+ L L EQ Q A+Q E +Q +++ EQ+ +++ +
Sbjct: 651 ERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGRE 710
Query: 133 QEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLY 192
QE Q ++A + + A++ +A+A+ +A + + RE R L
Sbjct: 711 QELEQARREAQRQVEALE---RAAREKEALAKEHAGLAVQLVAAEREG-----RTLSEE- 761
Query: 193 LVTTMTLTQEDLFGQ--------SQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQ 244
T + L +E L G +Q E R + LL L E G +Q
Sbjct: 762 -ATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALL---LAKETLTGELAGLRQQ 817
Query: 245 MALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRT 304
+ ++ S E + ER + +R E A+E+ LQ E EL+
Sbjct: 818 IIATQEKASLDKELMAQKLVQAEREAQASLR--EQRAAHEEDLQRLQREKEAAWRELEAE 875
Query: 305 RDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQ----VSTAEKEREELKNRLHW 360
R + LQR EQ E + + L+ EL ++AA + + + AE E+++ +
Sbjct: 876 RAQLQSQLQR--EQEELLAR-LEAEKEELSEEIAALQQERDEGLLLAESEKQQALSLKES 932
Query: 361 QMKRLTENFEQAQLRILGLQTQVQSLRRTASSTGDGD 397
+ L+E + + + +++ +R A S + D
Sbjct: 933 EKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQD 969
Score = 31.9 bits (69), Expect = 4.3
Identities = 30/117 (25%), Positives = 50/117 (42%), Gaps = 4/117 (3%)
Query: 242 EKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGEL 301
E+Q R Q +L SE+ L+A + EE+A A+ + ++ + LG +
Sbjct: 956 ERQKRDAQSRQEQDRSTVNALTSELRDLRA---QREEAAAAHAQEVRRLQEQARDLGKQR 1012
Query: 302 DRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRL 358
D EA L+ E R L+ + E +R+L S+ +E EL+ L
Sbjct: 1013 DSCLREAEE-LRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSL 1068
>BC126911-1|AAI26912.1| 1132|Homo sapiens CROCC protein protein.
Length = 1132
Score = 49.6 bits (113), Expect = 2e-05
Identities = 74/346 (21%), Positives = 151/346 (43%), Gaps = 20/346 (5%)
Query: 28 RELEMK-FEGLATHTNMLMGS-KEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQ 85
R+L+++ G + L+G+ ++Q + E RAL++ + R++ D ++ +
Sbjct: 394 RQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAHEDAQRE 453
Query: 86 LQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDL 145
+Q R A +L+ ++ + ++++Q E+++ + K Q +EL D
Sbjct: 454 VQRLR----SANELLSREKSNLAH----SLQVAQQQAEELRQEREKLQAAQEELRRQRDR 505
Query: 146 LKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLF 205
L+ Q +DA Q A E+ R+L K + + L + + Q D+
Sbjct: 506 LEEEQ---EDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDML 562
Query: 206 GQSQSEIGRG-NKDQTVHVLLHNSLKPPEKPPERGGDE-KQMALLNQRISQLAENNISLK 263
++E+ K + V L S+ D +++ LN+ ++Q + L
Sbjct: 563 QAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLV 622
Query: 264 SEIERLKASVI---RTEESALANEKRLQEKMHECAQLGGELDRTRDEAS-RALQRAHEQT 319
+++E K+++ R E + QE++ E +L E+ R E S R ++A E
Sbjct: 623 AQLEEEKSALQGRQRQAEQEATVAREEQERLEEL-RLEQEVARQGLEGSLRVAEQAQEAL 681
Query: 320 ETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRL 365
E L+ ++L+ QLA Q+S E+E E+ + Q++ L
Sbjct: 682 EQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARREAQRQVEAL 727
Score = 37.5 bits (83), Expect = 0.086
Identities = 69/339 (20%), Positives = 140/339 (41%), Gaps = 28/339 (8%)
Query: 75 LRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINL------EIQRV 128
+ + + ++ Q+QD R +Y +Q L+ R+Q + EQ+ +
Sbjct: 387 IHSALHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQA 446
Query: 129 KLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARE---LNCAREKVVHIF 185
Q ++Q L +LL + L + Q +A+ AE+L +E L A+E++
Sbjct: 447 HEDAQREVQRLRSANELLSREKSNLAHSLQ---VAQQQAEELRQEREKLQAAQEELRRQR 503
Query: 186 RYLYSLY--LVTTMTLTQEDL-FGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDE 242
L V + +L Q E G + L+ +R +
Sbjct: 504 DRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQ 563
Query: 243 KQMALLNQRISQLAENNISLKSEIERLKASVIRTEES----ALANEKRLQEKMHECAQLG 298
+ A + + +++ + L+ + +L+A ++S + NE Q+K+ + +L
Sbjct: 564 AEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKL-DLNRLV 622
Query: 299 GELDRTRDEASRALQRAHEQTETVRKCLQTTVAE--LERQLAAS--RAQVSTAEKEREEL 354
+L+ + A + QR EQ TV + Q + E LE+++A + AE+ +E L
Sbjct: 623 AQLEEEK-SALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEAL 681
Query: 355 KNR---LHWQMKRLTENFEQAQLRILGLQTQVQSLRRTA 390
+ + L + +L E Q ++ G + +++ RR A
Sbjct: 682 EQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARREA 720
Score = 35.5 bits (78), Expect = 0.35
Identities = 87/397 (21%), Positives = 155/397 (39%), Gaps = 34/397 (8%)
Query: 17 RCQHRETQNKLRELEMKFEGLATHT---NMLMGS-KEQAFEQEVNVRALKQCYREAREEI 72
R + Q+ L +L E LA N L+ +E+ + R +Q AREE
Sbjct: 591 RAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQ 650
Query: 73 DELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKF 132
+ L L EQ Q A+Q E +Q +++ EQ+ +++ +
Sbjct: 651 ERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGRE 710
Query: 133 QEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLY 192
QE Q ++A + + A++ +A+A+ +A + + RE R L
Sbjct: 711 QELEQARREAQRQVEALE---RAAREKEALAKEHAGLAVQLVAAEREG-----RTLSEE- 761
Query: 193 LVTTMTLTQEDLFGQ--------SQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQ 244
T + L +E L G +Q E R + LL L E G +Q
Sbjct: 762 -ATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALL---LAKETLTGELAGLRQQ 817
Query: 245 MALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRT 304
+ ++ S E + ER + +R E A+E+ LQ E EL+
Sbjct: 818 IIATQEKASLDKELMAQKLVQAEREAQASLR--EQRAAHEEDLQRLQREKEAAWRELEAE 875
Query: 305 RDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQ----VSTAEKEREELKNRLHW 360
R + LQR EQ E + + L+ EL ++AA + + + AE E+++ +
Sbjct: 876 RAQLQSQLQR--EQEELLAR-LEAEKEELSEEIAALQQERDEGLLLAESEKQQALSLKES 932
Query: 361 QMKRLTENFEQAQLRILGLQTQVQSLRRTASSTGDGD 397
+ L+E + + + +++ +R A S + D
Sbjct: 933 EKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQD 969
Score = 31.9 bits (69), Expect = 4.3
Identities = 30/117 (25%), Positives = 50/117 (42%), Gaps = 4/117 (3%)
Query: 242 EKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGEL 301
E+Q R Q +L SE+ L+A + EE+A A+ + ++ + LG +
Sbjct: 956 ERQKRDAQSRQEQDRSTVNALTSELRDLRA---QREEAAAAHAQEVRRLQEQARDLGKQR 1012
Query: 302 DRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRL 358
D EA L+ E R L+ + E +R+L S+ +E EL+ L
Sbjct: 1013 DSCLREAEE-LRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSL 1068
>AL049569-4|CAI20365.1| 1898|Homo sapiens ciliary rootlet
coiled-coil, rootletin protein.
Length = 1898
Score = 49.6 bits (113), Expect = 2e-05
Identities = 74/346 (21%), Positives = 151/346 (43%), Gaps = 20/346 (5%)
Query: 28 RELEMK-FEGLATHTNMLMGS-KEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQ 85
R+L+++ G + L+G+ ++Q + E RAL++ + R++ D ++ +
Sbjct: 412 RQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAHEDAQRE 471
Query: 86 LQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDL 145
+Q R A +L+ ++ + ++++Q E+++ + K Q +EL D
Sbjct: 472 VQRLR----SANELLSREKSNLAH----SLQVAQQQAEELRQEREKLQAAQEELRRQRDR 523
Query: 146 LKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLF 205
L+ Q +DA Q A E+ R+L K + + L + + Q D+
Sbjct: 524 LEEEQ---EDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDML 580
Query: 206 GQSQSEIGRG-NKDQTVHVLLHNSLKPPEKPPERGGDE-KQMALLNQRISQLAENNISLK 263
++E+ K + V L S+ D +++ LN+ ++Q + L
Sbjct: 581 QAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLV 640
Query: 264 SEIERLKASVI---RTEESALANEKRLQEKMHECAQLGGELDRTRDEAS-RALQRAHEQT 319
+++E K+++ R E + QE++ E +L E+ R E S R ++A E
Sbjct: 641 AQLEEEKSALQGRQRQAEQEATVAREEQERLEEL-RLEQEVARQGLEGSLRVAEQAQEAL 699
Query: 320 ETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRL 365
E L+ ++L+ QLA Q+S E+E E+ + Q++ L
Sbjct: 700 EQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARREAQRQVEAL 745
Score = 46.8 bits (106), Expect = 1e-04
Identities = 65/312 (20%), Positives = 131/312 (41%), Gaps = 22/312 (7%)
Query: 92 KYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDLLKATQM 151
++LQ + + +R + R ++ E + ++ + +A + ++
Sbjct: 1394 EFLQELRSAQRERDELRTQTSALNRQLAEMEAERDSATSRARQLQKAVAESEEARRSVDG 1453
Query: 152 RLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLY--------SLYLVTTMTLTQED 203
RL Q A+ E + + RE ++V + R L S ++ M +
Sbjct: 1454 RLSGVQAELALQEESVRRSERERRATLDQVATLERSLQATESELRASQEKISKMKANETK 1513
Query: 204 LFGQSQ--SEIGRGNKDQTVHVLLHNSLKPPEKPPERGG---DEKQMALLNQRIS----Q 254
L G + E+ ++ +TV + L E R G E Q L R+ Q
Sbjct: 1514 LEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLGLSDREAQAQALQDRVDSLQRQ 1573
Query: 255 LAENNI---SLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRA 311
+A++ + +L+ +ERL ++ + EES A +++ AQ L+ TRD+ +
Sbjct: 1574 VADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSASLNSTRDK-NLH 1632
Query: 312 LQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRL-HWQMKRLTENFE 370
LQ+A E R+ LQ + + L+ +R Q S+ ++ + L+ + +++R+ +
Sbjct: 1633 LQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQRVEAEGQ 1692
Query: 371 QAQLRILGLQTQ 382
QLR + Q Q
Sbjct: 1693 LQQLREVLRQRQ 1704
Score = 40.3 bits (90), Expect = 0.012
Identities = 89/421 (21%), Positives = 168/421 (39%), Gaps = 49/421 (11%)
Query: 17 RCQHRETQNKL-RELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDEL 75
R H E +L RE E + L L ++ EQE L + E E +E+
Sbjct: 869 RAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQR--EQE---ELLARLEAEKEELSEEI 923
Query: 76 RTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEK 135
L +E+++ L + QA L E ++ I+LE++R K Q +
Sbjct: 924 AALQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSR 983
Query: 136 LQELAPIPDLLKATQMRLKDAQQAQAIAEH-----NAEQLAREL-----NCARE------ 179
++ + L +++R AQ+ +A A H ++ AR+L +C RE
Sbjct: 984 QEQDRSTVNAL-TSELRDLRAQREEAAAAHAQEVRRLQEQARDLGKQRDSCLREAEELRT 1042
Query: 180 --KVVHIFRYLYSLYLVTTMTLTQEDLFGQS---------QSEIGRGNKDQTVHVLLHNS 228
+++ R L+ +E G+ + +G G K++ +
Sbjct: 1043 QLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEE 1102
Query: 229 LKPPEKPPERGGDEKQMALLN--QRISQLAENNISLKSEIERLKASVIRTEESALANEKR 286
L+ K E ++A + Q+++ L E ++ E L+ + E S L +
Sbjct: 1103 LRSAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRE 1162
Query: 287 LQEKMHECAQLGGELDRTRDEASR-----AL-QRAHEQTETVRKCLQTTVAELERQLAAS 340
LQE + L E R E + AL +RA +++ L+ + + E L
Sbjct: 1163 LQELRRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVM 1222
Query: 341 RAQVSTAEKEREELKNRLHWQMKRLTENFEQA------QL-RILGLQTQVQSLRRTASST 393
R ++ A+++ +E + + +RL + E+A QL GL+ ++++ R A+
Sbjct: 1223 RQELQVAQRKLQEQEGEFRTRERRLLGSLEEARGTEKQQLDHARGLELKLEAARAEAAEL 1282
Query: 394 G 394
G
Sbjct: 1283 G 1283
Score = 39.5 bits (88), Expect = 0.021
Identities = 88/395 (22%), Positives = 164/395 (41%), Gaps = 50/395 (12%)
Query: 21 RETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMK 80
R+ Q + E E E + L G + + QE +VR + RE R +D++ TL +
Sbjct: 1435 RQLQKAVAESE---EARRSVDGRLSGVQAELALQEESVRRSE---RERRATLDQVATLER 1488
Query: 81 EQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINL-EIQRVKLKFQEKLQEL 139
LQ + +Q+ + + + R+ E ++ E + VKL+ Q + E
Sbjct: 1489 S----LQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLE- 1543
Query: 140 APIPDLLKATQMRLKDAQ-QAQAIAEHNAEQLARELNCAREKV----VHIFRYLYSLYLV 194
L+ +++ L D + QAQA+ + + L R++ + K + + R +L V
Sbjct: 1544 ----GELQRSRLGLSDREAQAQALQDR-VDSLQRQVADSEVKAGTLQLTVERLNGALAKV 1598
Query: 195 TTMTLTQED-------LFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMAL 247
D QS + + +D+ +H L +L E +R ++++
Sbjct: 1599 EESEGALRDKVRGLTEALAQSSASLN-STRDKNLH--LQKALTACEH--DRQVLQERLDA 1653
Query: 248 LNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLG-GE------ 300
Q +S+ + + SL +++ L+ V E + E +LQ+ Q GE
Sbjct: 1654 ARQALSEARKQSSSLGEQVQTLRGEVADLELQRVEAEGQLQQLREVLRQRQEGEAAALNT 1713
Query: 301 LDRTRDEASR------ALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKER--- 351
+ + +DE +LQRA Q E ++ ++ + LE+ A R + E+E+
Sbjct: 1714 VQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVEREKLRS 1773
Query: 352 EELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSL 386
E RL + RL A+L + Q Q+Q L
Sbjct: 1774 HEDTVRLSAEKGRLDRTLTGAELELAEAQRQIQQL 1808
Score = 39.5 bits (88), Expect = 0.021
Identities = 72/368 (19%), Positives = 139/368 (37%), Gaps = 18/368 (4%)
Query: 23 TQNKLRELEMKFEGLATHTNMLMGSKEQAFE----QEVNVRALKQCYREAREEIDELRTL 78
T+++LR + K + + L G K + E E L+ R E+ R
Sbjct: 1493 TESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLG 1552
Query: 79 MKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKL-- 136
+ ++ Q Q + + Q+ V + + R++ + +++ + ++K+
Sbjct: 1553 LSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLTVERLNGAL-AKVEESEGALRDKVRG 1611
Query: 137 --QELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLV 194
+ LA L +T+ + Q+A EH+ + L L+ AR+ + + SL
Sbjct: 1612 LTEALAQSSASLNSTRDKNLHLQKALTACEHDRQVLQERLDAARQALSEARKQSSSLG-E 1670
Query: 195 TTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQ 254
TL E + Q G Q VL + + LL +R+
Sbjct: 1671 QVQTLRGEVADLELQRVEAEGQLQQLREVLRQRQEGEAAALNTVQKLQDERRLLQERLGS 1730
Query: 255 LAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQR 314
L L++E ++ S +R E+ +A + L + E +L D R A +
Sbjct: 1731 LQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVERE--KLRSHEDTVRLSAEKG--- 1785
Query: 315 AHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQL 374
+ + + +AE +RQ+ AQV E+ + + Q ++L E +L
Sbjct: 1786 ---RLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDAQQQQLELQQEVERL 1842
Query: 375 RILGLQTQ 382
R QT+
Sbjct: 1843 RSAQAQTE 1850
Score = 37.5 bits (83), Expect = 0.086
Identities = 69/339 (20%), Positives = 140/339 (41%), Gaps = 28/339 (8%)
Query: 75 LRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINL------EIQRV 128
+ + + ++ Q+QD R +Y +Q L+ R+Q + EQ+ +
Sbjct: 405 IHSALHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQA 464
Query: 129 KLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARE---LNCAREKVVHIF 185
Q ++Q L +LL + L + Q +A+ AE+L +E L A+E++
Sbjct: 465 HEDAQREVQRLRSANELLSREKSNLAHSLQ---VAQQQAEELRQEREKLQAAQEELRRQR 521
Query: 186 RYLYSLY--LVTTMTLTQEDL-FGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDE 242
L V + +L Q E G + L+ +R +
Sbjct: 522 DRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQ 581
Query: 243 KQMALLNQRISQLAENNISLKSEIERLKASVIRTEES----ALANEKRLQEKMHECAQLG 298
+ A + + +++ + L+ + +L+A ++S + NE Q+K+ + +L
Sbjct: 582 AEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKL-DLNRLV 640
Query: 299 GELDRTRDEASRALQRAHEQTETVRKCLQTTVAE--LERQLAAS--RAQVSTAEKEREEL 354
+L+ + A + QR EQ TV + Q + E LE+++A + AE+ +E L
Sbjct: 641 AQLEEEK-SALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEAL 699
Query: 355 KNR---LHWQMKRLTENFEQAQLRILGLQTQVQSLRRTA 390
+ + L + +L E Q ++ G + +++ RR A
Sbjct: 700 EQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARREA 738
Score = 35.5 bits (78), Expect = 0.35
Identities = 87/397 (21%), Positives = 155/397 (39%), Gaps = 34/397 (8%)
Query: 17 RCQHRETQNKLRELEMKFEGLATHT---NMLMGS-KEQAFEQEVNVRALKQCYREAREEI 72
R + Q+ L +L E LA N L+ +E+ + R +Q AREE
Sbjct: 609 RAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQ 668
Query: 73 DELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKF 132
+ L L EQ Q A+Q E +Q +++ EQ+ +++ +
Sbjct: 669 ERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGRE 728
Query: 133 QEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLY 192
QE Q ++A + + A++ +A+A+ +A + + RE R L
Sbjct: 729 QELEQARREAQRQVEALE---RAAREKEALAKEHAGLAVQLVAAEREG-----RTLSEE- 779
Query: 193 LVTTMTLTQEDLFGQ--------SQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQ 244
T + L +E L G +Q E R + LL L E G +Q
Sbjct: 780 -ATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALL---LAKETLTGELAGLRQQ 835
Query: 245 MALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRT 304
+ ++ S E + ER + +R E A+E+ LQ E EL+
Sbjct: 836 IIATQEKASLDKELMAQKLVQAEREAQASLR--EQRAAHEEDLQRLQREKEAAWRELEAE 893
Query: 305 RDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQ----VSTAEKEREELKNRLHW 360
R + LQR EQ E + + L+ EL ++AA + + + AE E+++ +
Sbjct: 894 RAQLQSQLQR--EQEELLAR-LEAEKEELSEEIAALQQERDEGLLLAESEKQQALSLKES 950
Query: 361 QMKRLTENFEQAQLRILGLQTQVQSLRRTASSTGDGD 397
+ L+E + + + +++ +R A S + D
Sbjct: 951 EKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQD 987
>AL049569-3|CAI20363.1| 2017|Homo sapiens ciliary rootlet
coiled-coil, rootletin protein.
Length = 2017
Score = 49.6 bits (113), Expect = 2e-05
Identities = 74/346 (21%), Positives = 151/346 (43%), Gaps = 20/346 (5%)
Query: 28 RELEMK-FEGLATHTNMLMGS-KEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQ 85
R+L+++ G + L+G+ ++Q + E RAL++ + R++ D ++ +
Sbjct: 531 RQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAHEDAQRE 590
Query: 86 LQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDL 145
+Q R A +L+ ++ + ++++Q E+++ + K Q +EL D
Sbjct: 591 VQRLR----SANELLSREKSNLAH----SLQVAQQQAEELRQEREKLQAAQEELRRQRDR 642
Query: 146 LKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLF 205
L+ Q +DA Q A E+ R+L K + + L + + Q D+
Sbjct: 643 LEEEQ---EDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDML 699
Query: 206 GQSQSEIGRG-NKDQTVHVLLHNSLKPPEKPPERGGDE-KQMALLNQRISQLAENNISLK 263
++E+ K + V L S+ D +++ LN+ ++Q + L
Sbjct: 700 QAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLV 759
Query: 264 SEIERLKASVI---RTEESALANEKRLQEKMHECAQLGGELDRTRDEAS-RALQRAHEQT 319
+++E K+++ R E + QE++ E +L E+ R E S R ++A E
Sbjct: 760 AQLEEEKSALQGRQRQAEQEATVAREEQERLEEL-RLEQEVARQGLEGSLRVAEQAQEAL 818
Query: 320 ETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRL 365
E L+ ++L+ QLA Q+S E+E E+ + Q++ L
Sbjct: 819 EQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARREAQRQVEAL 864
Score = 46.8 bits (106), Expect = 1e-04
Identities = 65/312 (20%), Positives = 131/312 (41%), Gaps = 22/312 (7%)
Query: 92 KYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDLLKATQM 151
++LQ + + +R + R ++ E + ++ + +A + ++
Sbjct: 1513 EFLQELRSAQRERDELRTQTSALNRQLAEMEAERDSATSRARQLQKAVAESEEARRSVDG 1572
Query: 152 RLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLY--------SLYLVTTMTLTQED 203
RL Q A+ E + + RE ++V + R L S ++ M +
Sbjct: 1573 RLSGVQAELALQEESVRRSERERRATLDQVATLERSLQATESELRASQEKISKMKANETK 1632
Query: 204 LFGQSQ--SEIGRGNKDQTVHVLLHNSLKPPEKPPERGG---DEKQMALLNQRIS----Q 254
L G + E+ ++ +TV + L E R G E Q L R+ Q
Sbjct: 1633 LEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLGLSDREAQAQALQDRVDSLQRQ 1692
Query: 255 LAENNI---SLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRA 311
+A++ + +L+ +ERL ++ + EES A +++ AQ L+ TRD+ +
Sbjct: 1693 VADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSASLNSTRDK-NLH 1751
Query: 312 LQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRL-HWQMKRLTENFE 370
LQ+A E R+ LQ + + L+ +R Q S+ ++ + L+ + +++R+ +
Sbjct: 1752 LQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQRVEAEGQ 1811
Query: 371 QAQLRILGLQTQ 382
QLR + Q Q
Sbjct: 1812 LQQLREVLRQRQ 1823
Score = 40.3 bits (90), Expect = 0.012
Identities = 89/421 (21%), Positives = 168/421 (39%), Gaps = 49/421 (11%)
Query: 17 RCQHRETQNKL-RELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDEL 75
R H E +L RE E + L L ++ EQE L + E E +E+
Sbjct: 988 RAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQR--EQE---ELLARLEAEKEELSEEI 1042
Query: 76 RTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEK 135
L +E+++ L + QA L E ++ I+LE++R K Q +
Sbjct: 1043 AALQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSR 1102
Query: 136 LQELAPIPDLLKATQMRLKDAQQAQAIAEH-----NAEQLAREL-----NCARE------ 179
++ + L +++R AQ+ +A A H ++ AR+L +C RE
Sbjct: 1103 QEQDRSTVNAL-TSELRDLRAQREEAAAAHAQEVRRLQEQARDLGKQRDSCLREAEELRT 1161
Query: 180 --KVVHIFRYLYSLYLVTTMTLTQEDLFGQS---------QSEIGRGNKDQTVHVLLHNS 228
+++ R L+ +E G+ + +G G K++ +
Sbjct: 1162 QLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEE 1221
Query: 229 LKPPEKPPERGGDEKQMALLN--QRISQLAENNISLKSEIERLKASVIRTEESALANEKR 286
L+ K E ++A + Q+++ L E ++ E L+ + E S L +
Sbjct: 1222 LRSAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRE 1281
Query: 287 LQEKMHECAQLGGELDRTRDEASR-----AL-QRAHEQTETVRKCLQTTVAELERQLAAS 340
LQE + L E R E + AL +RA +++ L+ + + E L
Sbjct: 1282 LQELRRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVM 1341
Query: 341 RAQVSTAEKEREELKNRLHWQMKRLTENFEQA------QL-RILGLQTQVQSLRRTASST 393
R ++ A+++ +E + + +RL + E+A QL GL+ ++++ R A+
Sbjct: 1342 RQELQVAQRKLQEQEGEFRTRERRLLGSLEEARGTEKQQLDHARGLELKLEAARAEAAEL 1401
Query: 394 G 394
G
Sbjct: 1402 G 1402
Score = 39.5 bits (88), Expect = 0.021
Identities = 88/395 (22%), Positives = 164/395 (41%), Gaps = 50/395 (12%)
Query: 21 RETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMK 80
R+ Q + E E E + L G + + QE +VR + RE R +D++ TL +
Sbjct: 1554 RQLQKAVAESE---EARRSVDGRLSGVQAELALQEESVRRSE---RERRATLDQVATLER 1607
Query: 81 EQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINL-EIQRVKLKFQEKLQEL 139
LQ + +Q+ + + + R+ E ++ E + VKL+ Q + E
Sbjct: 1608 S----LQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLE- 1662
Query: 140 APIPDLLKATQMRLKDAQ-QAQAIAEHNAEQLARELNCAREKV----VHIFRYLYSLYLV 194
L+ +++ L D + QAQA+ + + L R++ + K + + R +L V
Sbjct: 1663 ----GELQRSRLGLSDREAQAQALQDR-VDSLQRQVADSEVKAGTLQLTVERLNGALAKV 1717
Query: 195 TTMTLTQED-------LFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMAL 247
D QS + + +D+ +H L +L E +R ++++
Sbjct: 1718 EESEGALRDKVRGLTEALAQSSASLN-STRDKNLH--LQKALTACEH--DRQVLQERLDA 1772
Query: 248 LNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLG-GE------ 300
Q +S+ + + SL +++ L+ V E + E +LQ+ Q GE
Sbjct: 1773 ARQALSEARKQSSSLGEQVQTLRGEVADLELQRVEAEGQLQQLREVLRQRQEGEAAALNT 1832
Query: 301 LDRTRDEASR------ALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKER--- 351
+ + +DE +LQRA Q E ++ ++ + LE+ A R + E+E+
Sbjct: 1833 VQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVEREKLRS 1892
Query: 352 EELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSL 386
E RL + RL A+L + Q Q+Q L
Sbjct: 1893 HEDTVRLSAEKGRLDRTLTGAELELAEAQRQIQQL 1927
Score = 39.5 bits (88), Expect = 0.021
Identities = 72/368 (19%), Positives = 139/368 (37%), Gaps = 18/368 (4%)
Query: 23 TQNKLRELEMKFEGLATHTNMLMGSKEQAFE----QEVNVRALKQCYREAREEIDELRTL 78
T+++LR + K + + L G K + E E L+ R E+ R
Sbjct: 1612 TESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLG 1671
Query: 79 MKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKL-- 136
+ ++ Q Q + + Q+ V + + R++ + +++ + ++K+
Sbjct: 1672 LSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLTVERLNGAL-AKVEESEGALRDKVRG 1730
Query: 137 --QELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLV 194
+ LA L +T+ + Q+A EH+ + L L+ AR+ + + SL
Sbjct: 1731 LTEALAQSSASLNSTRDKNLHLQKALTACEHDRQVLQERLDAARQALSEARKQSSSLG-E 1789
Query: 195 TTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQ 254
TL E + Q G Q VL + + LL +R+
Sbjct: 1790 QVQTLRGEVADLELQRVEAEGQLQQLREVLRQRQEGEAAALNTVQKLQDERRLLQERLGS 1849
Query: 255 LAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQR 314
L L++E ++ S +R E+ +A + L + E +L D R A +
Sbjct: 1850 LQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVERE--KLRSHEDTVRLSAEKG--- 1904
Query: 315 AHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQL 374
+ + + +AE +RQ+ AQV E+ + + Q ++L E +L
Sbjct: 1905 ---RLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDAQQQQLELQQEVERL 1961
Query: 375 RILGLQTQ 382
R QT+
Sbjct: 1962 RSAQAQTE 1969
Score = 37.5 bits (83), Expect = 0.086
Identities = 69/339 (20%), Positives = 140/339 (41%), Gaps = 28/339 (8%)
Query: 75 LRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINL------EIQRV 128
+ + + ++ Q+QD R +Y +Q L+ R+Q + EQ+ +
Sbjct: 524 IHSALHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQA 583
Query: 129 KLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARE---LNCAREKVVHIF 185
Q ++Q L +LL + L + Q +A+ AE+L +E L A+E++
Sbjct: 584 HEDAQREVQRLRSANELLSREKSNLAHSLQ---VAQQQAEELRQEREKLQAAQEELRRQR 640
Query: 186 RYLYSLY--LVTTMTLTQEDL-FGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDE 242
L V + +L Q E G + L+ +R +
Sbjct: 641 DRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQ 700
Query: 243 KQMALLNQRISQLAENNISLKSEIERLKASVIRTEES----ALANEKRLQEKMHECAQLG 298
+ A + + +++ + L+ + +L+A ++S + NE Q+K+ + +L
Sbjct: 701 AEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKL-DLNRLV 759
Query: 299 GELDRTRDEASRALQRAHEQTETVRKCLQTTVAE--LERQLAAS--RAQVSTAEKEREEL 354
+L+ + A + QR EQ TV + Q + E LE+++A + AE+ +E L
Sbjct: 760 AQLEEEK-SALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEAL 818
Query: 355 KNR---LHWQMKRLTENFEQAQLRILGLQTQVQSLRRTA 390
+ + L + +L E Q ++ G + +++ RR A
Sbjct: 819 EQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARREA 857
Score = 35.5 bits (78), Expect = 0.35
Identities = 87/397 (21%), Positives = 155/397 (39%), Gaps = 34/397 (8%)
Query: 17 RCQHRETQNKLRELEMKFEGLATHT---NMLMGS-KEQAFEQEVNVRALKQCYREAREEI 72
R + Q+ L +L E LA N L+ +E+ + R +Q AREE
Sbjct: 728 RAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQ 787
Query: 73 DELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKF 132
+ L L EQ Q A+Q E +Q +++ EQ+ +++ +
Sbjct: 788 ERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGRE 847
Query: 133 QEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLY 192
QE Q ++A + + A++ +A+A+ +A + + RE R L
Sbjct: 848 QELEQARREAQRQVEALE---RAAREKEALAKEHAGLAVQLVAAEREG-----RTLSEE- 898
Query: 193 LVTTMTLTQEDLFGQ--------SQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQ 244
T + L +E L G +Q E R + LL L E G +Q
Sbjct: 899 -ATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALL---LAKETLTGELAGLRQQ 954
Query: 245 MALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRT 304
+ ++ S E + ER + +R E A+E+ LQ E EL+
Sbjct: 955 IIATQEKASLDKELMAQKLVQAEREAQASLR--EQRAAHEEDLQRLQREKEAAWRELEAE 1012
Query: 305 RDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQ----VSTAEKEREELKNRLHW 360
R + LQR EQ E + + L+ EL ++AA + + + AE E+++ +
Sbjct: 1013 RAQLQSQLQR--EQEELLAR-LEAEKEELSEEIAALQQERDEGLLLAESEKQQALSLKES 1069
Query: 361 QMKRLTENFEQAQLRILGLQTQVQSLRRTASSTGDGD 397
+ L+E + + + +++ +R A S + D
Sbjct: 1070 EKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQD 1106
>AB007914-1|BAA32290.2| 1919|Homo sapiens KIAA0445 protein protein.
Length = 1919
Score = 49.6 bits (113), Expect = 2e-05
Identities = 74/346 (21%), Positives = 151/346 (43%), Gaps = 20/346 (5%)
Query: 28 RELEMK-FEGLATHTNMLMGS-KEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQ 85
R+L+++ G + L+G+ ++Q + E RAL++ + R++ D ++ +
Sbjct: 433 RQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAHEDAQRE 492
Query: 86 LQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDL 145
+Q R A +L+ ++ + ++++Q E+++ + K Q +EL D
Sbjct: 493 VQRLR----SANELLSREKSNLAH----SLQVAQQQAEELRQEREKLQAAQEELRRQRDR 544
Query: 146 LKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLF 205
L+ Q +DA Q A E+ R+L K + + L + + Q D+
Sbjct: 545 LEEEQ---EDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDML 601
Query: 206 GQSQSEIGRG-NKDQTVHVLLHNSLKPPEKPPERGGDE-KQMALLNQRISQLAENNISLK 263
++E+ K + V L S+ D +++ LN+ ++Q + L
Sbjct: 602 QAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLV 661
Query: 264 SEIERLKASVI---RTEESALANEKRLQEKMHECAQLGGELDRTRDEAS-RALQRAHEQT 319
+++E K+++ R E + QE++ E +L E+ R E S R ++A E
Sbjct: 662 AQLEEEKSALQGRQRQAEQEATVAREEQERLEEL-RLEQEVARQGLEGSLRVAEQAQEAL 720
Query: 320 ETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRL 365
E L+ ++L+ QLA Q+S E+E E+ + Q++ L
Sbjct: 721 EQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARREAQRQVEAL 766
Score = 46.8 bits (106), Expect = 1e-04
Identities = 65/312 (20%), Positives = 131/312 (41%), Gaps = 22/312 (7%)
Query: 92 KYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDLLKATQM 151
++LQ + + +R + R ++ E + ++ + +A + ++
Sbjct: 1415 EFLQELRSAQRERDELRTQTSALNRQLAEMEAERDSATSRARQLQKAVAESEEARRSVDG 1474
Query: 152 RLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLY--------SLYLVTTMTLTQED 203
RL Q A+ E + + RE ++V + R L S ++ M +
Sbjct: 1475 RLSGVQAELALQEESVRRSERERRATLDQVATLERSLQATESELRASQEKISKMKANETK 1534
Query: 204 LFGQSQ--SEIGRGNKDQTVHVLLHNSLKPPEKPPERGG---DEKQMALLNQRIS----Q 254
L G + E+ ++ +TV + L E R G E Q L R+ Q
Sbjct: 1535 LEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLGLSDREAQAQALQDRVDSLQRQ 1594
Query: 255 LAENNI---SLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRA 311
+A++ + +L+ +ERL ++ + EES A +++ AQ L+ TRD+ +
Sbjct: 1595 VADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSASLNSTRDK-NLH 1653
Query: 312 LQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRL-HWQMKRLTENFE 370
LQ+A E R+ LQ + + L+ +R Q S+ ++ + L+ + +++R+ +
Sbjct: 1654 LQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQRVEAEGQ 1713
Query: 371 QAQLRILGLQTQ 382
QLR + Q Q
Sbjct: 1714 LQQLREVLRQRQ 1725
Score = 40.3 bits (90), Expect = 0.012
Identities = 89/421 (21%), Positives = 168/421 (39%), Gaps = 49/421 (11%)
Query: 17 RCQHRETQNKL-RELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDEL 75
R H E +L RE E + L L ++ EQE L + E E +E+
Sbjct: 890 RAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQR--EQE---ELLARLEAEKEELSEEI 944
Query: 76 RTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEK 135
L +E+++ L + QA L E ++ I+LE++R K Q +
Sbjct: 945 AALQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSR 1004
Query: 136 LQELAPIPDLLKATQMRLKDAQQAQAIAEH-----NAEQLAREL-----NCARE------ 179
++ + L +++R AQ+ +A A H ++ AR+L +C RE
Sbjct: 1005 QEQDRSTVNAL-TSELRDLRAQREEAAAAHAQEVRRLQEQARDLGKQRDSCLREAEELRT 1063
Query: 180 --KVVHIFRYLYSLYLVTTMTLTQEDLFGQS---------QSEIGRGNKDQTVHVLLHNS 228
+++ R L+ +E G+ + +G G K++ +
Sbjct: 1064 QLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEE 1123
Query: 229 LKPPEKPPERGGDEKQMALLN--QRISQLAENNISLKSEIERLKASVIRTEESALANEKR 286
L+ K E ++A + Q+++ L E ++ E L+ + E S L +
Sbjct: 1124 LRSAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRE 1183
Query: 287 LQEKMHECAQLGGELDRTRDEASR-----AL-QRAHEQTETVRKCLQTTVAELERQLAAS 340
LQE + L E R E + AL +RA +++ L+ + + E L
Sbjct: 1184 LQELRRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVM 1243
Query: 341 RAQVSTAEKEREELKNRLHWQMKRLTENFEQA------QL-RILGLQTQVQSLRRTASST 393
R ++ A+++ +E + + +RL + E+A QL GL+ ++++ R A+
Sbjct: 1244 RQELQVAQRKLQEQEGEFRTRERRLLGSLEEARGTEKQQLDHARGLELKLEAARAEAAEL 1303
Query: 394 G 394
G
Sbjct: 1304 G 1304
Score = 39.5 bits (88), Expect = 0.021
Identities = 88/395 (22%), Positives = 164/395 (41%), Gaps = 50/395 (12%)
Query: 21 RETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMK 80
R+ Q + E E E + L G + + QE +VR + RE R +D++ TL +
Sbjct: 1456 RQLQKAVAESE---EARRSVDGRLSGVQAELALQEESVRRSE---RERRATLDQVATLER 1509
Query: 81 EQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINL-EIQRVKLKFQEKLQEL 139
LQ + +Q+ + + + R+ E ++ E + VKL+ Q + E
Sbjct: 1510 S----LQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLE- 1564
Query: 140 APIPDLLKATQMRLKDAQ-QAQAIAEHNAEQLARELNCAREKV----VHIFRYLYSLYLV 194
L+ +++ L D + QAQA+ + + L R++ + K + + R +L V
Sbjct: 1565 ----GELQRSRLGLSDREAQAQALQDR-VDSLQRQVADSEVKAGTLQLTVERLNGALAKV 1619
Query: 195 TTMTLTQED-------LFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMAL 247
D QS + + +D+ +H L +L E +R ++++
Sbjct: 1620 EESEGALRDKVRGLTEALAQSSASLN-STRDKNLH--LQKALTACEH--DRQVLQERLDA 1674
Query: 248 LNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLG-GE------ 300
Q +S+ + + SL +++ L+ V E + E +LQ+ Q GE
Sbjct: 1675 ARQALSEARKQSSSLGEQVQTLRGEVADLELQRVEAEGQLQQLREVLRQRQEGEAAALNT 1734
Query: 301 LDRTRDEASR------ALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKER--- 351
+ + +DE +LQRA Q E ++ ++ + LE+ A R + E+E+
Sbjct: 1735 VQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVEREKLRS 1794
Query: 352 EELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSL 386
E RL + RL A+L + Q Q+Q L
Sbjct: 1795 HEDTVRLSAEKGRLDRTLTGAELELAEAQRQIQQL 1829
Score = 39.5 bits (88), Expect = 0.021
Identities = 72/368 (19%), Positives = 139/368 (37%), Gaps = 18/368 (4%)
Query: 23 TQNKLRELEMKFEGLATHTNMLMGSKEQAFE----QEVNVRALKQCYREAREEIDELRTL 78
T+++LR + K + + L G K + E E L+ R E+ R
Sbjct: 1514 TESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLG 1573
Query: 79 MKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKL-- 136
+ ++ Q Q + + Q+ V + + R++ + +++ + ++K+
Sbjct: 1574 LSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLTVERLNGAL-AKVEESEGALRDKVRG 1632
Query: 137 --QELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLV 194
+ LA L +T+ + Q+A EH+ + L L+ AR+ + + SL
Sbjct: 1633 LTEALAQSSASLNSTRDKNLHLQKALTACEHDRQVLQERLDAARQALSEARKQSSSLG-E 1691
Query: 195 TTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQ 254
TL E + Q G Q VL + + LL +R+
Sbjct: 1692 QVQTLRGEVADLELQRVEAEGQLQQLREVLRQRQEGEAAALNTVQKLQDERRLLQERLGS 1751
Query: 255 LAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQR 314
L L++E ++ S +R E+ +A + L + E +L D R A +
Sbjct: 1752 LQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVERE--KLRSHEDTVRLSAEKG--- 1806
Query: 315 AHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQL 374
+ + + +AE +RQ+ AQV E+ + + Q ++L E +L
Sbjct: 1807 ---RLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDAQQQQLELQQEVERL 1863
Query: 375 RILGLQTQ 382
R QT+
Sbjct: 1864 RSAQAQTE 1871
Score = 37.5 bits (83), Expect = 0.086
Identities = 69/339 (20%), Positives = 140/339 (41%), Gaps = 28/339 (8%)
Query: 75 LRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINL------EIQRV 128
+ + + ++ Q+QD R +Y +Q L+ R+Q + EQ+ +
Sbjct: 426 IHSALHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQA 485
Query: 129 KLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARE---LNCAREKVVHIF 185
Q ++Q L +LL + L + Q +A+ AE+L +E L A+E++
Sbjct: 486 HEDAQREVQRLRSANELLSREKSNLAHSLQ---VAQQQAEELRQEREKLQAAQEELRRQR 542
Query: 186 RYLYSLY--LVTTMTLTQEDL-FGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDE 242
L V + +L Q E G + L+ +R +
Sbjct: 543 DRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQ 602
Query: 243 KQMALLNQRISQLAENNISLKSEIERLKASVIRTEES----ALANEKRLQEKMHECAQLG 298
+ A + + +++ + L+ + +L+A ++S + NE Q+K+ + +L
Sbjct: 603 AEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKL-DLNRLV 661
Query: 299 GELDRTRDEASRALQRAHEQTETVRKCLQTTVAE--LERQLAAS--RAQVSTAEKEREEL 354
+L+ + A + QR EQ TV + Q + E LE+++A + AE+ +E L
Sbjct: 662 AQLEEEK-SALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEAL 720
Query: 355 KNR---LHWQMKRLTENFEQAQLRILGLQTQVQSLRRTA 390
+ + L + +L E Q ++ G + +++ RR A
Sbjct: 721 EQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARREA 759
Score = 35.5 bits (78), Expect = 0.35
Identities = 87/397 (21%), Positives = 155/397 (39%), Gaps = 34/397 (8%)
Query: 17 RCQHRETQNKLRELEMKFEGLATHT---NMLMGS-KEQAFEQEVNVRALKQCYREAREEI 72
R + Q+ L +L E LA N L+ +E+ + R +Q AREE
Sbjct: 630 RAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQ 689
Query: 73 DELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKF 132
+ L L EQ Q A+Q E +Q +++ EQ+ +++ +
Sbjct: 690 ERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGRE 749
Query: 133 QEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLY 192
QE Q ++A + + A++ +A+A+ +A + + RE R L
Sbjct: 750 QELEQARREAQRQVEALE---RAAREKEALAKEHAGLAVQLVAAEREG-----RTLSEE- 800
Query: 193 LVTTMTLTQEDLFGQ--------SQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQ 244
T + L +E L G +Q E R + LL L E G +Q
Sbjct: 801 -ATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALL---LAKETLTGELAGLRQQ 856
Query: 245 MALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRT 304
+ ++ S E + ER + +R E A+E+ LQ E EL+
Sbjct: 857 IIATQEKASLDKELMAQKLVQAEREAQASLR--EQRAAHEEDLQRLQREKEAAWRELEAE 914
Query: 305 RDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQ----VSTAEKEREELKNRLHW 360
R + LQR EQ E + + L+ EL ++AA + + + AE E+++ +
Sbjct: 915 RAQLQSQLQR--EQEELLAR-LEAEKEELSEEIAALQQERDEGLLLAESEKQQALSLKES 971
Query: 361 QMKRLTENFEQAQLRILGLQTQVQSLRRTASSTGDGD 397
+ L+E + + + +++ +R A S + D
Sbjct: 972 EKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQD 1008
>BC127772-1|AAI27773.1| 863|Homo sapiens KIF5C protein protein.
Length = 863
Score = 49.2 bits (112), Expect = 3e-05
Identities = 76/378 (20%), Positives = 157/378 (41%), Gaps = 22/378 (5%)
Query: 22 ETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKE 81
E + R+L+ K + + + + K+Q +Q+ + + ++ Y + +EE+ L+
Sbjct: 326 EISSLYRQLDDKDDEINQQSQLAEKLKQQMLDQDELLASTRRDYEKIQEELTRLQI---- 381
Query: 82 QNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAP 141
+N+ +D + LQA + + Q TR +EQ+ E+ + +EL+
Sbjct: 382 ENEAAKDEVKEVLQALEELAVNYDQKSQEVEDKTRANEQLTDELAQKTTTLTTTQRELSQ 441
Query: 142 IPDL-----LKATQ---MRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYL 193
+ +L +AT+ + LKD + I N + ++N E+ + R S
Sbjct: 442 LQELSNHQKKRATEILNLLLKDLGEIGGIIGTNDVKTLADVNGVIEEEFTMARLYISKMK 501
Query: 194 VTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRIS 253
+L +S + + L L + + M + Q+
Sbjct: 502 SEVKSLVNRSKQLESAQMDSNRKMNASERELAACQLLISQHEAKIKSLTDYMQNMEQKRR 561
Query: 254 QLAENNISLKSEIERLKASVIRTEESALANEK----RLQEKMHECAQLGGELDRTRDEAS 309
QL E+ SL E+ +L+A E S EK RLQ+ L +++ R+
Sbjct: 562 QLEESQDSLSEELAKLRAQEKMHEVSFQDKEKEHLTRLQDAEEMKKALEQQMESHREAHQ 621
Query: 310 RALQRAHEQTETVRKCLQTTVAELERQLAASRAQVST----AEKEREELKNRLHWQMKRL 365
+ L R ++ E +K + + +L ++L + ++S+ + E +E + +L ++ L
Sbjct: 622 KQLSRLRDEIEEKQKIID-EIRDLNQKLQLEQEKLSSDYNKLKIEDQEREMKLE-KLLLL 679
Query: 366 TENFEQAQLRILGLQTQV 383
+ EQA+ + GL+ V
Sbjct: 680 NDKREQAREDLKGLEETV 697
>BC110287-1|AAI10288.1| 725|Homo sapiens KIF5C protein protein.
Length = 725
Score = 49.2 bits (112), Expect = 3e-05
Identities = 76/378 (20%), Positives = 157/378 (41%), Gaps = 22/378 (5%)
Query: 22 ETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKE 81
E + R+L+ K + + + + K+Q +Q+ + + ++ Y + +EE+ L+
Sbjct: 188 EISSLYRQLDDKDDEINQQSQLAEKLKQQMLDQDELLASTRRDYEKIQEELTRLQI---- 243
Query: 82 QNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAP 141
+N+ +D + LQA + + Q TR +EQ+ E+ + +EL+
Sbjct: 244 ENEAAKDEVKEVLQALEELAVNYDQKSQEVEDKTRANEQLTDELAQKTTTLTTTQRELSQ 303
Query: 142 IPDL-----LKATQ---MRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYL 193
+ +L +AT+ + LKD + I N + ++N E+ + R S
Sbjct: 304 LQELSNHQKKRATEILNLLLKDLGEIGGIIGTNDVKTLADVNGVIEEEFTMARLYISKMK 363
Query: 194 VTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRIS 253
+L +S + + L L + + M + Q+
Sbjct: 364 SEVKSLVNRSKQLESAQMDSNRKMNASERELAACQLLISQHEAKIKSLTDYMQNMEQKRR 423
Query: 254 QLAENNISLKSEIERLKASVIRTEESALANEK----RLQEKMHECAQLGGELDRTRDEAS 309
QL E+ SL E+ +L+A E S EK RLQ+ L +++ R+
Sbjct: 424 QLEESQDSLSEELAKLRAQEKMHEVSFQDKEKEHLTRLQDAEEMKKALEQQMESHREAHQ 483
Query: 310 RALQRAHEQTETVRKCLQTTVAELERQLAASRAQVST----AEKEREELKNRLHWQMKRL 365
+ L R ++ E +K + + +L ++L + ++S+ + E +E + +L ++ L
Sbjct: 484 KQLSRLRDEIEEKQKIID-EIRDLNQKLQLEQEKLSSDYNKLKIEDQEREMKLE-KLLLL 541
Query: 366 TENFEQAQLRILGLQTQV 383
+ EQA+ + GL+ V
Sbjct: 542 NDKREQAREDLKGLEETV 559
>AY610514-1|AAT37906.1| 1302|Homo sapiens paracingulin protein.
Length = 1302
Score = 49.2 bits (112), Expect = 3e-05
Identities = 91/394 (23%), Positives = 163/394 (41%), Gaps = 33/394 (8%)
Query: 17 RCQHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELR 76
R + RE + EL + L G ++ ++E + ALK +E D+
Sbjct: 719 RSEDREKGALIEELLQAKQDLQDLLIAKEGREDLLRKRERELTALKGALKEEVSSHDQEM 778
Query: 77 TLMKEQND-QLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKL--KFQ 133
+KEQ D +LQ R +A + VE NT +Q E+ RVKL +
Sbjct: 779 DKLKEQYDAELQALRESVEEATKNVE------VLASRSNTSEQDQAGTEM-RVKLLQEEN 831
Query: 134 EKLQELAP-IPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLY 192
EKLQ + + + Q +++D + +A A+ ++ E+ E +VH +
Sbjct: 832 EKLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQLEEALVHARKE--EKE 889
Query: 193 LVTTMTLTQEDLFG---------QSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEK 243
V+ + +L G Q Q ++ K+++ LK E ER K
Sbjct: 890 AVSARRALENELEGAQGNLSQTTQEQKQLSEKLKEESEQKEQLRRLKN-EMENERWHLGK 948
Query: 244 QMALLNQRISQLAE----NNISLKSEIERLKASVIR--TEESALANEKRLQ-EKMHECAQ 296
+ L + ++ + E + + L+++++ K R E EK L+ EK A
Sbjct: 949 TIEKLQKEMADIVEASRTSTLELQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAM 1008
Query: 297 LGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAAS---RAQVSTAEKEREE 353
+ R +E R QRA ++ T R+ L+ T+ +LE +L A + S K+ E
Sbjct: 1009 KMQDGMRLMEEELRDYQRAQDEALTKRQLLEQTLKDLEYELEAKSHLKDDRSRLVKQMEA 1068
Query: 354 LKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLR 387
++L +++ N + RI + Q++ LR
Sbjct: 1069 KVSQLEMELEEERNNSDLLSERISRSREQMEQLR 1102
Score = 41.1 bits (92), Expect = 0.007
Identities = 70/385 (18%), Positives = 145/385 (37%), Gaps = 10/385 (2%)
Query: 21 RETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDE-LRTLM 79
R +N+L + L ++ EQ+ +R LK R + + + L
Sbjct: 895 RALENELEGAQGNLSQTTQEQKQLSEKLKEESEQKEQLRRLKNEMENERWHLGKTIEKLQ 954
Query: 80 KEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQEL 139
KE D ++ R L+ Q ++E + + R ++ LE ++ +L + +
Sbjct: 955 KEMADIVEASRTSTLELQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDGM 1014
Query: 140 APIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYL-VTTMT 198
+ + L+ Q +A + + E + L EL R + + V+ +
Sbjct: 1015 RLMEEELRDYQRAQDEALTKRQLLEQTLKDLEYELEAKSHLKDDRSRLVKQMEAKVSQLE 1074
Query: 199 LTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAEN 258
+ E+ S R ++ + L N L E+ + + +++L Q L
Sbjct: 1075 MELEEERNNSDLLSERISRSREQMEQLRNGLLQ-ERAARQDLECGKISLERQN-KDLKSR 1132
Query: 259 NISLKSEIERLKASVIRTEESALAN-EKRLQEKMHECAQL---GGELDRTRDEASRALQR 314
I L+ K ++ E+ +A E RL+ + + A L L+R E +
Sbjct: 1133 IIHLEGSYRSSKEGLVVQMEARIAELEDRLESEERDRANLQLSNRRLERKVKELVMQVDD 1192
Query: 315 AHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQL 374
H + L + ++RQ+ + ++ E +++L+ L QM + E+ Q QL
Sbjct: 1193 EHLSLTDQKDQLSLRLKAMKRQVEEAEEEIDRLESSKKKLQRELEEQMD-MNEHL-QGQL 1250
Query: 375 RILGLQTQVQSLRRTASSTGDGDGE 399
+ +++ L D D +
Sbjct: 1251 NSMKKDLRLKKLPSKVLDDMDDDDD 1275
Score = 38.7 bits (86), Expect = 0.037
Identities = 68/352 (19%), Positives = 144/352 (40%), Gaps = 25/352 (7%)
Query: 48 KEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQX 107
KE+ N+ L+ + E EE L+ ++E +L+ + Q + E+ + +
Sbjct: 641 KEERERMRANLEELRSQHNEKVEENSTLQQRLEESEGELRKNLEELFQVKMEREQHQTEI 700
Query: 108 XXXXXXNTRISEQINL----EIQRVKLKFQEKLQELAPIPDLLKATQMR----LKDAQQA 159
+ + ++++ E + +E LQ + DLL A + R K ++
Sbjct: 701 RDLQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEGREDLLRKREREL 760
Query: 160 QAIAEHNAEQLA---RELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQ-SEIGRG 215
A+ E+++ +E++ +E+ + L V T E L +S SE +
Sbjct: 761 TALKGALKEEVSSHDQEMDKLKEQYDAELQALRES--VEEATKNVEVLASRSNTSEQDQA 818
Query: 216 NKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIR 275
+ V +L + K + E E+++A L ++I L + K +++ + + +
Sbjct: 819 GTEMRVKLLQEENEKLQGRSEEL---ERRVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQ 875
Query: 276 TEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELER 335
EE+ + K +E + L EL+ + S+ Q + +E +++ +E +
Sbjct: 876 LEEALVHARKEEKEAVSARRALENELEGAQGNLSQTTQEQKQLSEKLKE-----ESEQKE 930
Query: 336 QLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLR 387
QL R + E ER L + K + + E ++ L LQ Q+ +
Sbjct: 931 QL---RRLKNEMENERWHLGKTIEKLQKEMADIVEASRTSTLELQNQLDEYK 979
>AL355355-6|CAI16549.1| 577|Homo sapiens optineurin protein.
Length = 577
Score = 49.2 bits (112), Expect = 3e-05
Identities = 50/241 (20%), Positives = 112/241 (46%), Gaps = 13/241 (5%)
Query: 46 GSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRR 105
G+K +E+ V L C RE ++++ L +KE +++ D+ K + +E Q
Sbjct: 221 GAKNYFEHEELTVSQLLLCLREGNQKVERLEVALKEAKERVSDFEKKTSNRSE-IETQTE 279
Query: 106 QXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPI-PDLLKATQMRLKDAQQAQAIAE 164
+ E + E++ + L+ +EL L KA M+ + ++ QA+
Sbjct: 280 GSTEKENDEEKGPETVGSEVEALNLQVTSLFKELQEAHTKLSKAELMKKRLQEKCQALER 339
Query: 165 HNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVL 224
N+ + ELN ++++V+ + L L + + ++ + + +++ E + Q H
Sbjct: 340 KNS-AIPSELN-EKQELVYTNKKL-ELQVESMLSEIKMEQ-AKTEDEKSKLTVLQMTHNK 395
Query: 225 L----HNSLKPPEKPPERGGDEKQMALLNQRIS--QLAENNISLKS-EIERLKASVIRTE 277
L +N+LK E+ + ++ A+L + +LAE ++ K +++ +K ++ + E
Sbjct: 396 LLQEHNNALKTIEELTRKESEKVDRAVLKELSEKLELAEKALASKQLQMDEMKQTIAKQE 455
Query: 278 E 278
E
Sbjct: 456 E 456
>AL355355-5|CAI16550.1| 571|Homo sapiens optineurin protein.
Length = 571
Score = 49.2 bits (112), Expect = 3e-05
Identities = 50/241 (20%), Positives = 112/241 (46%), Gaps = 13/241 (5%)
Query: 46 GSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRR 105
G+K +E+ V L C RE ++++ L +KE +++ D+ K + +E Q
Sbjct: 215 GAKNYFEHEELTVSQLLLCLREGNQKVERLEVALKEAKERVSDFEKKTSNRSE-IETQTE 273
Query: 106 QXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPI-PDLLKATQMRLKDAQQAQAIAE 164
+ E + E++ + L+ +EL L KA M+ + ++ QA+
Sbjct: 274 GSTEKENDEEKGPETVGSEVEALNLQVTSLFKELQEAHTKLSKAELMKKRLQEKCQALER 333
Query: 165 HNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVL 224
N+ + ELN ++++V+ + L L + + ++ + + +++ E + Q H
Sbjct: 334 KNS-AIPSELN-EKQELVYTNKKL-ELQVESMLSEIKMEQ-AKTEDEKSKLTVLQMTHNK 389
Query: 225 L----HNSLKPPEKPPERGGDEKQMALLNQRIS--QLAENNISLKS-EIERLKASVIRTE 277
L +N+LK E+ + ++ A+L + +LAE ++ K +++ +K ++ + E
Sbjct: 390 LLQEHNNALKTIEELTRKESEKVDRAVLKELSEKLELAEKALASKQLQMDEMKQTIAKQE 449
Query: 278 E 278
E
Sbjct: 450 E 450
Score = 35.5 bits (78), Expect = 0.35
Identities = 57/301 (18%), Positives = 125/301 (41%), Gaps = 17/301 (5%)
Query: 61 LKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQ 120
L Q +E E +L+ MK N+Q R + L A E+Q+ + + E+
Sbjct: 40 LLQQMKELLTENHQLKEAMK-LNNQAMKGRFEELSAW--TEKQKEERQFFEIQSKEAKER 96
Query: 121 INLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREK 180
+ + + K +E+L +L + ++++ D++ +A AE +QL ++ + +
Sbjct: 97 L-MALSHENEKLKEELGKLKGKSE--RSSEDPTDDSRLPRAEAEQEKDQLRTQVVRLQAE 153
Query: 181 VVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNS--LKPPEKPPER 238
+ + L L + + ED F + + + G + +V + H+ + R
Sbjct: 154 KADLLGIVSELQLKLNSSGSSEDSFVEIR--MAEGEAEGSVKEIKHSPGPTRTVSTGTSR 211
Query: 239 GGDEKQMALLNQR--ISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQ 296
D + ++ +SQL ++ERL+ ++ +E EK+ + Q
Sbjct: 212 SADGAKNYFEHEELTVSQLLLCLREGNQKVERLEVALKEAKERVSDFEKKTSNRSEIETQ 271
Query: 297 LGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKN 356
G ++ DE ++ E + + L V L ++L + ++S AE ++ L+
Sbjct: 272 TEGSTEKENDE-----EKGPETVGSEVEALNLQVTSLFKELQEAHTKLSKAELMKKRLQE 326
Query: 357 R 357
+
Sbjct: 327 K 327
>AL136382-2|CAI23514.1| 636|Homo sapiens novel protein protein.
Length = 636
Score = 49.2 bits (112), Expect = 3e-05
Identities = 56/253 (22%), Positives = 105/253 (41%), Gaps = 16/253 (6%)
Query: 54 QEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXX 113
++ + ALK E+ EL+ + K+Q ++ Y+ + + Q+ E + +
Sbjct: 380 EKTTLAALKDEVVSVENELSELQEVEKKQKTLIEMYKTQVQKLQEAAEIVKSRCENLLHK 439
Query: 114 NTRISEQINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARE 173
N +I++ N +++++ + + L+EL + D L A + RL + Q++ +
Sbjct: 440 NNQITKTKNKNVEKMRGQMESHLKELERVCDSLTAAERRLHECQESLQCCKGKCADQEHT 499
Query: 174 LNCAREKVVHIFRYLYSLYLVTTMTLTQ---EDLFGQSQSEIGRGNKD------QTVHVL 224
+ + +V L L L L Q E+L Q ++ NK+ L
Sbjct: 500 IRELQGQVDGNHNLLTKLSLEEENCLIQLKCENL-QQKLEQMDAENKELEKKLANQEECL 558
Query: 225 LHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANE 284
H++LK EK E AL Q + L E + EIE++ + + L E
Sbjct: 559 KHSNLKFKEKSAE------YTALARQLEAALEEGRQKVAEEIEKMSSRESALQIKILDLE 612
Query: 285 KRLQEKMHECAQL 297
L++K E QL
Sbjct: 613 TELRKKNEEQNQL 625
>AF083322-1|AAC32373.1| 994|Homo sapiens centriole associated
protein CEP110 protein.
Length = 994
Score = 49.2 bits (112), Expect = 3e-05
Identities = 72/355 (20%), Positives = 149/355 (41%), Gaps = 20/355 (5%)
Query: 47 SKEQAFEQEVNVRALKQCYREAREEIDEL-RTLMKEQNDQ-LQDYRVKYLQAQQLVEEQR 104
S+++ E N+ L Q + E++EL RT+ K Q + D V+ L + +E+
Sbjct: 21 SEKEMEELHHNIDDLLQEKKSLECEVEELHRTVQKRQRQKDFIDGNVESLMTELEIEKSL 80
Query: 105 RQXXXXXXXNTRISEQI---NLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQA 161
+ I + + E++ E EL+ + K + DA+++
Sbjct: 81 KHHEDIVDEIECIEKTLLKRRSELREADRLLAEAESELSCTKEKTKNAVEKFTDAKRSLL 140
Query: 162 IAEHNAEQLARELNCAREKVVHIFRYLYSLYL----VTTMTLTQEDLFGQSQSEIGRGNK 217
E +AE+L R +V + L SL + + QE++ + + K
Sbjct: 141 QTESDAEELERRAQETAVNLVKADQQLRSLQADAKDLEQHKIKQEEILKEINKIVAA--K 198
Query: 218 DQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQ--RISQLAENNISL---KSEIERLKAS 272
D L K E+ + D +MA N+ + L E+ + L ++E+E+LK+
Sbjct: 199 DSDFQCLSKKKEKLTEELQKLQKDI-EMAERNEDHHLQVLKESEVLLQAKRAELEKLKSQ 257
Query: 273 VIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQ-TTVA 331
V ++ +++L K E L G + + + + AL+ +TE KC V
Sbjct: 258 VTSQQQEMAVLDRQLGHKKEELHLLQGSMVQAKADLQEALRLG--ETEVTEKCNHIREVK 315
Query: 332 ELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSL 386
L +L+ + +++ ER+ + ++++ EN + ++ +T++Q++
Sbjct: 316 SLLEELSFQKGELNVQISERKTQLTLIKQEIEKEEENLQVVLRQMSKHKTELQNI 370
Score = 41.9 bits (94), Expect = 0.004
Identities = 83/386 (21%), Positives = 159/386 (41%), Gaps = 49/386 (12%)
Query: 18 CQHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRT 77
C +E ++ + ++ + LA +L ++E + ++ N+ L R+ ++E+D+L
Sbjct: 453 CLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENSKMEQSNLEKLDLNVRKLQQELDQLN- 511
Query: 78 LMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRV--KLKFQEK 135
D+L + QQL +E+R + + +NL Q + K Q+
Sbjct: 512 -----RDKLSLHNDISAMQQQL-QEKREAVNSLQEELANVQDHLNLAKQDLLHTTKHQDV 565
Query: 136 L-QELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLV 194
L E + + R +D Q+ + + + L E+ + K+V
Sbjct: 566 LLSEQTRLQKDISEWANRFEDCQKEEETKQQQLQVLQNEIEENKLKLVQ----------- 614
Query: 195 TTMTLTQEDLFGQSQSEI-GRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRIS 253
QE +F + Q E +K +T V L EK D+K L+Q +S
Sbjct: 615 ------QEMMFQRLQKERESEESKLETSKVTLKEQQHQLEKELT---DQKSK--LDQVLS 663
Query: 254 QL--AENNISLKSEIER----LKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDE 307
++ AE + E ER L+ ++ +T+ E++L EK E L E D R +
Sbjct: 664 KVLAAEERVRTLQEEERWCESLEKTLSQTKRQLSEREQQLVEKSGELLALQKEADSMRAD 723
Query: 308 AS-------RALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKER---EELKNR 357
S ++A +Q ++++ L+ ++LE+ L + + S +KE E +
Sbjct: 724 FSLLRNQFLTERKKAEKQVASLKEALKIQRSQLEKNLLEQKQENSCIQKEMATIELVAQD 783
Query: 358 LHWQMKRLTENFEQAQLRILGLQTQV 383
H + +RL + Q Q L+ Q+
Sbjct: 784 NHERARRLMKELNQMQYEYTELKKQM 809
Score = 33.1 bits (72), Expect = 1.8
Identities = 30/127 (23%), Positives = 63/127 (49%), Gaps = 7/127 (5%)
Query: 242 EKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQE-KMHECAQLGGE 300
EK+ L + Q++++ L++ ++ L+ + L +++R+ E + + A L +
Sbjct: 347 EKEEENLQVVLRQMSKHKTELQNILDMLQLENHELQGLKLQHDQRVSELEKTQVAVLEEK 406
Query: 301 LDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAE---KEREELKNR 357
L+ + + Q+ + E ++ L+ E+ER A SRA S E KE+E+L+ +
Sbjct: 407 LEL--ENLQQISQQQKGEIEWQKQLLERDKREIERMTAESRALQSCVECLSKEKEDLQEK 464
Query: 358 LH-WQMK 363
W+ K
Sbjct: 465 CDIWEKK 471
>AC108512-1|AAX82030.1| 684|Homo sapiens unknown protein.
Length = 684
Score = 49.2 bits (112), Expect = 3e-05
Identities = 76/378 (20%), Positives = 157/378 (41%), Gaps = 22/378 (5%)
Query: 22 ETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKE 81
E + R+L+ K + + + + K+Q +Q+ + + ++ Y + +EE+ L+
Sbjct: 147 EISSLYRQLDDKDDEINQQSQLAEKLKQQMLDQDELLASTRRDYEKIQEELTRLQI---- 202
Query: 82 QNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAP 141
+N+ +D + LQA + + Q TR +EQ+ E+ + +EL+
Sbjct: 203 ENEAAKDEVKEVLQALEELAVNYDQKSQEVEDKTRANEQLTDELAQKTTTLTTTQRELSQ 262
Query: 142 IPDL-----LKATQ---MRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYL 193
+ +L +AT+ + LKD + I N + ++N E+ + R S
Sbjct: 263 LQELSNHQKKRATEILNLLLKDLGEIGGIIGTNDVKTLADVNGVIEEEFTMARLYISKMK 322
Query: 194 VTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRIS 253
+L +S + + L L + + M + Q+
Sbjct: 323 SEVKSLVNRSKQLESAQMDSNRKMNASERELAACQLLISQHEAKIKSLTDYMQNMEQKRR 382
Query: 254 QLAENNISLKSEIERLKASVIRTEESALANEK----RLQEKMHECAQLGGELDRTRDEAS 309
QL E+ SL E+ +L+A E S EK RLQ+ L +++ R+
Sbjct: 383 QLEESQDSLSEELAKLRAQEKMHEVSFQDKEKEHLTRLQDAEEMKKALEQQMESHREAHQ 442
Query: 310 RALQRAHEQTETVRKCLQTTVAELERQLAASRAQVST----AEKEREELKNRLHWQMKRL 365
+ L R ++ E +K + + +L ++L + ++S+ + E +E + +L ++ L
Sbjct: 443 KQLSRLRDEIEEKQKIID-EIRDLNQKLQLEQEKLSSDYNKLKIEDQEREMKLE-KLLLL 500
Query: 366 TENFEQAQLRILGLQTQV 383
+ EQA+ + GL+ V
Sbjct: 501 NDKREQAREDLKGLEETV 518
>AB033055-1|BAA86543.1| 696|Homo sapiens KIAA1229 protein protein.
Length = 696
Score = 49.2 bits (112), Expect = 3e-05
Identities = 56/253 (22%), Positives = 105/253 (41%), Gaps = 16/253 (6%)
Query: 54 QEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXX 113
++ + ALK E+ EL+ + K+Q ++ Y+ + + Q+ E + +
Sbjct: 440 EKTTLAALKDEVVSVENELSELQEVEKKQKTLIEMYKTQVQKLQEAAEIVKSRCENLLHK 499
Query: 114 NTRISEQINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARE 173
N +I++ N +++++ + + L+EL + D L A + RL + Q++ +
Sbjct: 500 NNQITKTKNKNVEKMRGQMESHLKELERVCDSLTAAERRLHECQESLQCCKGKCADQEHT 559
Query: 174 LNCAREKVVHIFRYLYSLYLVTTMTLTQ---EDLFGQSQSEIGRGNKD------QTVHVL 224
+ + +V L L L L Q E+L Q ++ NK+ L
Sbjct: 560 IRELQGQVDGNHNLLTKLSLEEENCLIQLKCENL-QQKLEQMDAENKELEKKLANQEECL 618
Query: 225 LHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANE 284
H++LK EK E AL Q + L E + EIE++ + + L E
Sbjct: 619 KHSNLKFKEKSAE------YTALARQLEAALEEGRQKVAEEIEKMSSRESALQIKILDLE 672
Query: 285 KRLQEKMHECAQL 297
L++K E QL
Sbjct: 673 TELRKKNEEQNQL 685
>AB011103-1|BAA25457.2| 999|Homo sapiens KIAA0531 protein protein.
Length = 999
Score = 49.2 bits (112), Expect = 3e-05
Identities = 76/378 (20%), Positives = 157/378 (41%), Gaps = 22/378 (5%)
Query: 22 ETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKE 81
E + R+L+ K + + + + K+Q +Q+ + + ++ Y + +EE+ L+
Sbjct: 462 EISSLYRQLDDKDDEINQQSQLAEKLKQQMLDQDELLASTRRDYEKIQEELTRLQI---- 517
Query: 82 QNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAP 141
+N+ +D + LQA + + Q TR +EQ+ E+ + +EL+
Sbjct: 518 ENEAAKDEVKEVLQALEELAVNYDQKSQEVEDKTRANEQLTDELAQKTTTLTTTQRELSQ 577
Query: 142 IPDL-----LKATQ---MRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYL 193
+ +L +AT+ + LKD + I N + ++N E+ + R S
Sbjct: 578 LQELSNHQKKRATEILNLLLKDLGEIGGIIGTNDVKTLADVNGVIEEEFTMARLYISKMK 637
Query: 194 VTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRIS 253
+L +S + + L L + + M + Q+
Sbjct: 638 SEVKSLVNRSKQLESAQMDSNRKMNASERELAACQLLISQHEAKIKSLTDYMQNMEQKRR 697
Query: 254 QLAENNISLKSEIERLKASVIRTEESALANEK----RLQEKMHECAQLGGELDRTRDEAS 309
QL E+ SL E+ +L+A E S EK RLQ+ L +++ R+
Sbjct: 698 QLEESQDSLSEELAKLRAQEKMHEVSFQDKEKEHLTRLQDAEEMKKALEQQMESHREAHQ 757
Query: 310 RALQRAHEQTETVRKCLQTTVAELERQLAASRAQVST----AEKEREELKNRLHWQMKRL 365
+ L R ++ E +K + + +L ++L + ++S+ + E +E + +L ++ L
Sbjct: 758 KQLSRLRDEIEEKQKIID-EIRDLNQKLQLEQEKLSSDYNKLKIEDQEREMKLE-KLLLL 815
Query: 366 TENFEQAQLRILGLQTQV 383
+ EQA+ + GL+ V
Sbjct: 816 NDKREQAREDLKGLEETV 833
>BC132784-1|AAI32785.1| 1116|Homo sapiens ELKS/RAB6-interacting/CAST
family member 1 protein.
Length = 1116
Score = 48.8 bits (111), Expect = 3e-05
Identities = 86/398 (21%), Positives = 168/398 (42%), Gaps = 42/398 (10%)
Query: 21 RETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMK 80
+E K EL L T TN SK+ + ++ A +Q + E+D LR ++
Sbjct: 473 QELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLE 532
Query: 81 EQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRI---SEQINL---EIQRVKLKFQE 134
E+ L K Q Q + EE+ Q + ++N+ +I+ ++ + ++
Sbjct: 533 EKETMLNK---KTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRD 589
Query: 135 KLQELAPIPDLLKA-------TQMRLKDAQQAQAIAEHNAEQLARELN-CAREKVVHIFR 186
K ++++ + + +K+ T L ++A A E E+L + + REK I
Sbjct: 590 KEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDN 649
Query: 187 YLYSLY-LVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQM 245
Y L L ++L Q DL S+ E + + L + LK + ++
Sbjct: 650 YKKDLKDLKEKVSLLQGDL---SEKEASLLDLKEHASSLASSGLK----------KDSRL 696
Query: 246 ALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQ-LGGELDRT 304
L + Q E + ++S+++ + E+AL E R +M + Q L E+ R
Sbjct: 697 KTLEIALEQKKEECLKMESQLK-------KAHEAAL--EARASPEMSDRIQHLEREITRY 747
Query: 305 RDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKR 364
+DE+S+A E +++ ++ + ++++A QV K+ LK++ + K+
Sbjct: 748 KDESSKAQAEVDRLLEILKE-VENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKK 806
Query: 365 LTENFEQAQLRILGLQTQVQSLRRTASSTGDGDGENQE 402
+ E+A+ R L Q L+ + D E +E
Sbjct: 807 SAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEE 844
Score = 31.1 bits (67), Expect = 7.4
Identities = 62/348 (17%), Positives = 143/348 (41%), Gaps = 37/348 (10%)
Query: 24 QNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQN 83
Q L E E L H + L S +++ ++ L+ + +EE ++ + +K+ +
Sbjct: 665 QGDLSEKEASLLDLKEHASSLASS---GLKKDSRLKTLEIALEQKKEECLKMESQLKKAH 721
Query: 84 DQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQIN--LEI-QRVKLKFQEKLQELA 140
+ + R + + ++ R+ +++ +++ LEI + V+ + +K +++A
Sbjct: 722 EAALEARASPEMSDR-IQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIA 780
Query: 141 PIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLT 200
+ +K ++ + + + + + + Q+ E + + + L +L
Sbjct: 781 ELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQD-------SLR 833
Query: 201 QEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNI 260
++D + E R ++V + + ++ R EKQ+ L + ++
Sbjct: 834 KKDDRIEELEEALR----ESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKV----- 884
Query: 261 SLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTE 320
K E+E +KA + T++S E L A+ L+ + AL A + +
Sbjct: 885 --KQELESMKAKLSSTQQSLAEKETHLTNLR---AERRKHLEEVLEMKQEALLAAISEKD 939
Query: 321 TVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTEN 368
+A LE + + Q A +RE K+RL Q+K+ T+N
Sbjct: 940 -------ANIALLELSSSKKKTQEEVAALKRE--KDRLVQQLKQQTQN 978
Score = 31.1 bits (67), Expect = 7.4
Identities = 30/155 (19%), Positives = 68/155 (43%), Gaps = 9/155 (5%)
Query: 21 RETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMK 80
++ Q+ LR+ + + E L L S + E+E+ + + A ++++EL M+
Sbjct: 826 QQLQDSLRKKDDRIEELE---EALRESVQITAEREMVLAQEESARTNAEKQVEELLMAME 882
Query: 81 EQNDQLQDYRVKYLQAQQ-LVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQEL 139
+ +L+ + K QQ L E++ + E + ++ + + EK +
Sbjct: 883 KVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANI 942
Query: 140 APIPDLLKATQMRLKDAQQAQAIAEHNAEQLAREL 174
A LL+ + + K Q+ A + ++L ++L
Sbjct: 943 A----LLELSSSK-KKTQEEVAALKREKDRLVQQL 972
>BC132782-1|AAI32783.1| 1116|Homo sapiens ELKS/RAB6-interacting/CAST
family member 1 protein.
Length = 1116
Score = 48.8 bits (111), Expect = 3e-05
Identities = 86/398 (21%), Positives = 168/398 (42%), Gaps = 42/398 (10%)
Query: 21 RETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMK 80
+E K EL L T TN SK+ + ++ A +Q + E+D LR ++
Sbjct: 473 QELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLE 532
Query: 81 EQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRI---SEQINL---EIQRVKLKFQE 134
E+ L K Q Q + EE+ Q + ++N+ +I+ ++ + ++
Sbjct: 533 EKETMLNK---KTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRD 589
Query: 135 KLQELAPIPDLLKA-------TQMRLKDAQQAQAIAEHNAEQLARELN-CAREKVVHIFR 186
K ++++ + + +K+ T L ++A A E E+L + + REK I
Sbjct: 590 KEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDN 649
Query: 187 YLYSLY-LVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQM 245
Y L L ++L Q DL S+ E + + L + LK + ++
Sbjct: 650 YKKDLKDLKEKVSLLQGDL---SEKEASLLDLKEHASSLASSGLK----------KDSRL 696
Query: 246 ALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQ-LGGELDRT 304
L + Q E + ++S+++ + E+AL E R +M + Q L E+ R
Sbjct: 697 KTLEIALEQKKEECLKMESQLK-------KAHEAAL--EARASPEMSDRIQHLEREITRY 747
Query: 305 RDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKR 364
+DE+S+A E +++ ++ + ++++A QV K+ LK++ + K+
Sbjct: 748 KDESSKAQAEVDRLLEILKE-VENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKK 806
Query: 365 LTENFEQAQLRILGLQTQVQSLRRTASSTGDGDGENQE 402
+ E+A+ R L Q L+ + D E +E
Sbjct: 807 SAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEE 844
Score = 31.1 bits (67), Expect = 7.4
Identities = 62/348 (17%), Positives = 143/348 (41%), Gaps = 37/348 (10%)
Query: 24 QNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQN 83
Q L E E L H + L S +++ ++ L+ + +EE ++ + +K+ +
Sbjct: 665 QGDLSEKEASLLDLKEHASSLASS---GLKKDSRLKTLEIALEQKKEECLKMESQLKKAH 721
Query: 84 DQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQIN--LEI-QRVKLKFQEKLQELA 140
+ + R + + ++ R+ +++ +++ LEI + V+ + +K +++A
Sbjct: 722 EAALEARASPEMSDR-IQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIA 780
Query: 141 PIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLT 200
+ +K ++ + + + + + + Q+ E + + + L +L
Sbjct: 781 ELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQD-------SLR 833
Query: 201 QEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNI 260
++D + E R ++V + + ++ R EKQ+ L + ++
Sbjct: 834 KKDDRIEELEEALR----ESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKV----- 884
Query: 261 SLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTE 320
K E+E +KA + T++S E L A+ L+ + AL A + +
Sbjct: 885 --KQELESMKAKLSSTQQSLAEKETHLTNLR---AERRKHLEEVLEMKQEALLAAISEKD 939
Query: 321 TVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTEN 368
+A LE + + Q A +RE K+RL Q+K+ T+N
Sbjct: 940 -------ANIALLELSSSKKKTQEEVAALKRE--KDRLVQQLKQQTQN 978
Score = 31.1 bits (67), Expect = 7.4
Identities = 30/155 (19%), Positives = 68/155 (43%), Gaps = 9/155 (5%)
Query: 21 RETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMK 80
++ Q+ LR+ + + E L L S + E+E+ + + A ++++EL M+
Sbjct: 826 QQLQDSLRKKDDRIEELE---EALRESVQITAEREMVLAQEESARTNAEKQVEELLMAME 882
Query: 81 EQNDQLQDYRVKYLQAQQ-LVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQEL 139
+ +L+ + K QQ L E++ + E + ++ + + EK +
Sbjct: 883 KVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANI 942
Query: 140 APIPDLLKATQMRLKDAQQAQAIAEHNAEQLAREL 174
A LL+ + + K Q+ A + ++L ++L
Sbjct: 943 A----LLELSSSK-KKTQEEVAALKREKDRLVQQL 972
>BC118918-1|AAI18919.1| 1302|Homo sapiens cingulin-like 1 protein.
Length = 1302
Score = 48.8 bits (111), Expect = 3e-05
Identities = 93/395 (23%), Positives = 167/395 (42%), Gaps = 35/395 (8%)
Query: 17 RCQHRETQNKLRELEMKFEGLATHTNMLMGSKEQAF---EQEVNVRALKQCYREAREEID 73
R + RE + EL + L ++L+ +EQ ++E + ALK +E D
Sbjct: 719 RSEDREKGALIEELLQAKQDLQ---DLLIAKEEQEDLLRKRERELTALKGALKEEVSSHD 775
Query: 74 ELRTLMKEQND-QLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKL-- 130
+ +KEQ D +LQ R +A + VE NT +Q E+ RVKL
Sbjct: 776 QEMDKLKEQYDAELQALRESVEEATKNVE------VLASRSNTSEQDQAGTEM-RVKLLQ 828
Query: 131 KFQEKLQELAP-IPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLY 189
+ EKLQ + + + Q +++D + +A A+ ++ E+ E +VH +
Sbjct: 829 EENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQLEEALVHARKEEK 888
Query: 190 SLY-----LVTTMTLTQEDLFG--QSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDE 242
L + Q +L Q Q ++ K+++ LK E ER
Sbjct: 889 EAVSARRALENELEAAQGNLSQTTQEQKQLSEKLKEESEQKEQLRRLKN-EMENERWHLG 947
Query: 243 KQMALLNQRISQLAE----NNISLKSEIERLKASVIR--TEESALANEKRLQ-EKMHECA 295
K + L + ++ + E + + L+++++ K R E EK L+ EK A
Sbjct: 948 KTIEKLQKEMADIVEASRTSTLELQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTA 1007
Query: 296 QLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAAS---RAQVSTAEKERE 352
+ R +E R QRA ++ T R+ L+ T+ +LE +L A + S K+ E
Sbjct: 1008 MKMQDEMRLMEEELRDYQRAQDEALTKRQLLEQTLKDLEYELEAKSHLKDDRSRLVKQME 1067
Query: 353 ELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLR 387
+ ++L +++ N + RI + Q++ LR
Sbjct: 1068 DKVSQLEMELEEERNNSDLLSERISRSREQMEQLR 1102
Score = 46.4 bits (105), Expect = 2e-04
Identities = 92/409 (22%), Positives = 174/409 (42%), Gaps = 43/409 (10%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQ----EVNVRALKQCYREAREEIDE 74
++ + Q + ELE + L L G + +A E E +R L++ AR+E E
Sbjct: 830 ENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQLEEALVHARKEEKE 889
Query: 75 L---RTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKL- 130
R ++ + + Q + Q Q+ + E+ ++ R+ + +E +R L
Sbjct: 890 AVSARRALENELEAAQGNLSQTTQEQKQLSEKLKEESEQKEQLRRLKNE--MENERWHLG 947
Query: 131 KFQEKLQ-ELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRY-L 188
K EKLQ E+A I + + + + L++ Q E N +LA +EK + + L
Sbjct: 948 KTIEKLQKEMADIVEASRTSTLELQN--QLDEYKEKNRRELAEMQRQLKEKTLEAEKSRL 1005
Query: 189 YSLYLVTTMTLTQEDL--FGQSQSEI--GRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQ 244
++ + M L +E+L + ++Q E R +QT+ L + +R KQ
Sbjct: 1006 TAMKMQDEMRLMEEELRDYQRAQDEALTKRQLLEQTLKDLEYELEAKSHLKDDRSRLVKQ 1065
Query: 245 MA------------------LLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKR 286
M LL++RIS+ E L++E+ + +A+ E ++ E++
Sbjct: 1066 MEDKVSQLEMELEEERNNSDLLSERISRSREQMEQLRNELLQERAARQDLECDKISLERQ 1125
Query: 287 LQEKMHECAQLGGELDRTRD------EASRA-LQRAHEQTETVRKCLQTTVAELERQLAA 339
++ L G +++ EA A L+ E E R LQ + LER++
Sbjct: 1126 NKDLKSRIIHLEGSYRSSKEGLVVQMEARIAELEDRLESEERDRANLQLSNRRLERKVKE 1185
Query: 340 SRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRR 388
QV + K++L ++K + E+A+ I L++ + L+R
Sbjct: 1186 LVMQVDDEHLSLTDQKDQLSLRLKAMKRQVEEAEEEIDRLESSKKKLQR 1234
Score = 45.2 bits (102), Expect = 4e-04
Identities = 76/390 (19%), Positives = 147/390 (37%), Gaps = 20/390 (5%)
Query: 21 RETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDE-LRTLM 79
R +N+L + L ++ EQ+ +R LK R + + + L
Sbjct: 895 RALENELEAAQGNLSQTTQEQKQLSEKLKEESEQKEQLRRLKNEMENERWHLGKTIEKLQ 954
Query: 80 KEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQEL 139
KE D ++ R L+ Q ++E + + R ++ LE ++ +L + E+
Sbjct: 955 KEMADIVEASRTSTLELQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDEM 1014
Query: 140 APIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCA---REKVVHIFRYLYSLYLVTT 196
+ + L+ Q +A + + E + L EL ++ + + +
Sbjct: 1015 RLMEEELRDYQRAQDEALTKRQLLEQTLKDLEYELEAKSHLKDDRSRLVKQMEDKVSQLE 1074
Query: 197 MTLTQE----DLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRI 252
M L +E DL + S R +Q + LL + ++ E+Q L RI
Sbjct: 1075 MELEEERNNSDLLSERISR-SREQMEQLRNELLQERAARQDLECDKISLERQNKDLKSRI 1133
Query: 253 SQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQL---GGELDRTRDEAS 309
L S +S E L V++ E E RL+ + + A L L+R E
Sbjct: 1134 IHLEG---SYRSSKEGL---VVQMEARIAELEDRLESEERDRANLQLSNRRLERKVKELV 1187
Query: 310 RALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENF 369
+ H + L + ++RQ+ + ++ E +++L+ L QM + E+
Sbjct: 1188 MQVDDEHLSLTDQKDQLSLRLKAMKRQVEEAEEEIDRLESSKKKLQRELEEQMD-MNEHL 1246
Query: 370 EQAQLRILGLQTQVQSLRRTASSTGDGDGE 399
Q QL + +++ L D D +
Sbjct: 1247 -QGQLNSMKKDLRLKKLPSKVLDDMDDDDD 1275
Score = 38.3 bits (85), Expect = 0.049
Identities = 67/352 (19%), Positives = 144/352 (40%), Gaps = 25/352 (7%)
Query: 48 KEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQX 107
KE+ N+ L+ + E EE L+ ++E +L+ + Q + E+ + +
Sbjct: 641 KEERERMRANLEELRSQHNEKVEENSTLQQRLEESEGELRKNLEELFQVKMEREQHQTEI 700
Query: 108 XXXXXXNTRISEQINL----EIQRVKLKFQEKLQELAPIPDLLKATQ----MRLKDAQQA 159
+ + ++++ E + +E LQ + DLL A + + K ++
Sbjct: 701 RDLQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEEQEDLLRKREREL 760
Query: 160 QAIAEHNAEQLA---RELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQ-SEIGRG 215
A+ E+++ +E++ +E+ + L V T E L +S SE +
Sbjct: 761 TALKGALKEEVSSHDQEMDKLKEQYDAELQALRES--VEEATKNVEVLASRSNTSEQDQA 818
Query: 216 NKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIR 275
+ V +L + K + E E+++A L ++I L + K +++ + + +
Sbjct: 819 GTEMRVKLLQEENEKLQGRSEEL---ERRVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQ 875
Query: 276 TEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELER 335
EE+ + K +E + L EL+ + S+ Q + +E +++ +E +
Sbjct: 876 LEEALVHARKEEKEAVSARRALENELEAAQGNLSQTTQEQKQLSEKLKE-----ESEQKE 930
Query: 336 QLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLR 387
QL R + E ER L + K + + E ++ L LQ Q+ +
Sbjct: 931 QL---RRLKNEMENERWHLGKTIEKLQKEMADIVEASRTSTLELQNQLDEYK 979
>BC112049-1|AAI12050.1| 1302|Homo sapiens cingulin-like 1 protein.
Length = 1302
Score = 48.8 bits (111), Expect = 3e-05
Identities = 93/395 (23%), Positives = 167/395 (42%), Gaps = 35/395 (8%)
Query: 17 RCQHRETQNKLRELEMKFEGLATHTNMLMGSKEQAF---EQEVNVRALKQCYREAREEID 73
R + RE + EL + L ++L+ +EQ ++E + ALK +E D
Sbjct: 719 RSEDREKGALIEELLQAKQDLQ---DLLIAKEEQEDLLRKRERELTALKGALKEEVSSHD 775
Query: 74 ELRTLMKEQND-QLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKL-- 130
+ +KEQ D +LQ R +A + VE NT +Q E+ RVKL
Sbjct: 776 QEMDKLKEQYDAELQALRESVEEATKNVE------VLASRSNTSEQDQAGTEM-RVKLLQ 828
Query: 131 KFQEKLQELAP-IPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLY 189
+ EKLQ + + + Q +++D + +A A+ ++ E+ E +VH +
Sbjct: 829 EENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQLEEALVHARKEEK 888
Query: 190 SLY-----LVTTMTLTQEDLFG--QSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDE 242
L + Q +L Q Q ++ K+++ LK E ER
Sbjct: 889 EAVSARRALENELEAAQGNLSQTTQEQKQLSEKLKEESEQKEQLRRLKN-EMENERWHLG 947
Query: 243 KQMALLNQRISQLAE----NNISLKSEIERLKASVIR--TEESALANEKRLQ-EKMHECA 295
K + L + ++ + E + + L+++++ K R E EK L+ EK A
Sbjct: 948 KTIEKLQKEMADIVEASRTSTLELQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTA 1007
Query: 296 QLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAAS---RAQVSTAEKERE 352
+ R +E R QRA ++ T R+ L+ T+ +LE +L A + S K+ E
Sbjct: 1008 MKMQDEMRLMEEELRDYQRAQDEALTKRQLLEQTLKDLEYELEAKSHLKDDRSRLVKQME 1067
Query: 353 ELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLR 387
+ ++L +++ N + RI + Q++ LR
Sbjct: 1068 DKVSQLEMELEEERNNSDLLSERISRSREQMEQLR 1102
Score = 46.4 bits (105), Expect = 2e-04
Identities = 92/409 (22%), Positives = 174/409 (42%), Gaps = 43/409 (10%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQ----EVNVRALKQCYREAREEIDE 74
++ + Q + ELE + L L G + +A E E +R L++ AR+E E
Sbjct: 830 ENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQLEEALVHARKEEKE 889
Query: 75 L---RTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKL- 130
R ++ + + Q + Q Q+ + E+ ++ R+ + +E +R L
Sbjct: 890 AVSARRALENELEAAQGNLSQTTQEQKQLSEKLKEESEQKEQLRRLKNE--MENERWHLG 947
Query: 131 KFQEKLQ-ELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRY-L 188
K EKLQ E+A I + + + + L++ Q E N +LA +EK + + L
Sbjct: 948 KTIEKLQKEMADIVEASRTSTLELQN--QLDEYKEKNRRELAEMQRQLKEKTLEAEKSRL 1005
Query: 189 YSLYLVTTMTLTQEDL--FGQSQSEI--GRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQ 244
++ + M L +E+L + ++Q E R +QT+ L + +R KQ
Sbjct: 1006 TAMKMQDEMRLMEEELRDYQRAQDEALTKRQLLEQTLKDLEYELEAKSHLKDDRSRLVKQ 1065
Query: 245 MA------------------LLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKR 286
M LL++RIS+ E L++E+ + +A+ E ++ E++
Sbjct: 1066 MEDKVSQLEMELEEERNNSDLLSERISRSREQMEQLRNELLQERAARQDLECDKISLERQ 1125
Query: 287 LQEKMHECAQLGGELDRTRD------EASRA-LQRAHEQTETVRKCLQTTVAELERQLAA 339
++ L G +++ EA A L+ E E R LQ + LER++
Sbjct: 1126 NKDLKSRIIHLEGSYRSSKEGLVVQMEARIAELEDRLESEERDRANLQLSNRRLERKVKE 1185
Query: 340 SRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRR 388
QV + K++L ++K + E+A+ I L++ + L+R
Sbjct: 1186 LVMQVDDEHLSLTDQKDQLSLRLKAMKRQVEEAEEEIDRLESSKKKLQR 1234
Score = 45.2 bits (102), Expect = 4e-04
Identities = 76/390 (19%), Positives = 147/390 (37%), Gaps = 20/390 (5%)
Query: 21 RETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDE-LRTLM 79
R +N+L + L ++ EQ+ +R LK R + + + L
Sbjct: 895 RALENELEAAQGNLSQTTQEQKQLSEKLKEESEQKEQLRRLKNEMENERWHLGKTIEKLQ 954
Query: 80 KEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQEL 139
KE D ++ R L+ Q ++E + + R ++ LE ++ +L + E+
Sbjct: 955 KEMADIVEASRTSTLELQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDEM 1014
Query: 140 APIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCA---REKVVHIFRYLYSLYLVTT 196
+ + L+ Q +A + + E + L EL ++ + + +
Sbjct: 1015 RLMEEELRDYQRAQDEALTKRQLLEQTLKDLEYELEAKSHLKDDRSRLVKQMEDKVSQLE 1074
Query: 197 MTLTQE----DLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRI 252
M L +E DL + S R +Q + LL + ++ E+Q L RI
Sbjct: 1075 MELEEERNNSDLLSERISR-SREQMEQLRNELLQERAARQDLECDKISLERQNKDLKSRI 1133
Query: 253 SQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQL---GGELDRTRDEAS 309
L S +S E L V++ E E RL+ + + A L L+R E
Sbjct: 1134 IHLEG---SYRSSKEGL---VVQMEARIAELEDRLESEERDRANLQLSNRRLERKVKELV 1187
Query: 310 RALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENF 369
+ H + L + ++RQ+ + ++ E +++L+ L QM + E+
Sbjct: 1188 MQVDDEHLSLTDQKDQLSLRLKAMKRQVEEAEEEIDRLESSKKKLQRELEEQMD-MNEHL 1246
Query: 370 EQAQLRILGLQTQVQSLRRTASSTGDGDGE 399
Q QL + +++ L D D +
Sbjct: 1247 -QGQLNSMKKDLRLKKLPSKVLDDMDDDDD 1275
Score = 38.3 bits (85), Expect = 0.049
Identities = 67/352 (19%), Positives = 144/352 (40%), Gaps = 25/352 (7%)
Query: 48 KEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQX 107
KE+ N+ L+ + E EE L+ ++E +L+ + Q + E+ + +
Sbjct: 641 KEERERMRANLEELRSQHNEKVEENSTLQQRLEESEGELRKNLEELFQVKMEREQHQTEI 700
Query: 108 XXXXXXNTRISEQINL----EIQRVKLKFQEKLQELAPIPDLLKATQ----MRLKDAQQA 159
+ + ++++ E + +E LQ + DLL A + + K ++
Sbjct: 701 RDLQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEEQEDLLRKREREL 760
Query: 160 QAIAEHNAEQLA---RELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQ-SEIGRG 215
A+ E+++ +E++ +E+ + L V T E L +S SE +
Sbjct: 761 TALKGALKEEVSSHDQEMDKLKEQYDAELQALRES--VEEATKNVEVLASRSNTSEQDQA 818
Query: 216 NKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIR 275
+ V +L + K + E E+++A L ++I L + K +++ + + +
Sbjct: 819 GTEMRVKLLQEENEKLQGRSEEL---ERRVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQ 875
Query: 276 TEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELER 335
EE+ + K +E + L EL+ + S+ Q + +E +++ +E +
Sbjct: 876 LEEALVHARKEEKEAVSARRALENELEAAQGNLSQTTQEQKQLSEKLKE-----ESEQKE 930
Query: 336 QLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLR 387
QL R + E ER L + K + + E ++ L LQ Q+ +
Sbjct: 931 QL---RRLKNEMENERWHLGKTIEKLQKEMADIVEASRTSTLELQNQLDEYK 979
>BC093827-1|AAH93827.1| 1302|Homo sapiens cingulin-like 1 protein.
Length = 1302
Score = 48.8 bits (111), Expect = 3e-05
Identities = 93/395 (23%), Positives = 167/395 (42%), Gaps = 35/395 (8%)
Query: 17 RCQHRETQNKLRELEMKFEGLATHTNMLMGSKEQAF---EQEVNVRALKQCYREAREEID 73
R + RE + EL + L ++L+ +EQ ++E + ALK +E D
Sbjct: 719 RSEDREKGALIEELLQAKQDLQ---DLLIAKEEQEDLLRKRERELTALKGALKEEVSSHD 775
Query: 74 ELRTLMKEQND-QLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKL-- 130
+ +KEQ D +LQ R +A + VE NT +Q E+ RVKL
Sbjct: 776 QEMDKLKEQYDAELQALRESVEEATKNVE------VLASRSNTSEQDQAGTEM-RVKLLQ 828
Query: 131 KFQEKLQELAP-IPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLY 189
+ EKLQ + + + Q +++D + +A A+ ++ E+ E +VH +
Sbjct: 829 EENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQLEEALVHARKEEK 888
Query: 190 SLY-----LVTTMTLTQEDLFG--QSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDE 242
L + Q +L Q Q ++ K+++ LK E ER
Sbjct: 889 EAVSARRALENELEAAQGNLSQTTQEQKQLSEKLKEESEQKEQLRRLKN-EMENERWHLG 947
Query: 243 KQMALLNQRISQLAE----NNISLKSEIERLKASVIR--TEESALANEKRLQ-EKMHECA 295
K + L + ++ + E + + L+++++ K R E EK L+ EK A
Sbjct: 948 KTIEKLQKEMADIVEASRTSTLELQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTA 1007
Query: 296 QLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAAS---RAQVSTAEKERE 352
+ R +E R QRA ++ T R+ L+ T+ +LE +L A + S K+ E
Sbjct: 1008 MKMQDEMRLMEEELRDYQRAQDEALTKRQLLEQTLKDLEYELEAKSHLKDDRSRLVKQME 1067
Query: 353 ELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLR 387
+ ++L +++ N + RI + Q++ LR
Sbjct: 1068 DKVSQLEMELEEERNNSDLLSERISRSREQMEQLR 1102
Score = 46.4 bits (105), Expect = 2e-04
Identities = 92/409 (22%), Positives = 174/409 (42%), Gaps = 43/409 (10%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQ----EVNVRALKQCYREAREEIDE 74
++ + Q + ELE + L L G + +A E E +R L++ AR+E E
Sbjct: 830 ENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQLEEALVHARKEEKE 889
Query: 75 L---RTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKL- 130
R ++ + + Q + Q Q+ + E+ ++ R+ + +E +R L
Sbjct: 890 AVSARRALENELEAAQGNLSQTTQEQKQLSEKLKEESEQKEQLRRLKNE--MENERWHLG 947
Query: 131 KFQEKLQ-ELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRY-L 188
K EKLQ E+A I + + + + L++ Q E N +LA +EK + + L
Sbjct: 948 KTIEKLQKEMADIVEASRTSTLELQN--QLDEYKEKNRRELAEMQRQLKEKTLEAEKSRL 1005
Query: 189 YSLYLVTTMTLTQEDL--FGQSQSEI--GRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQ 244
++ + M L +E+L + ++Q E R +QT+ L + +R KQ
Sbjct: 1006 TAMKMQDEMRLMEEELRDYQRAQDEALTKRQLLEQTLKDLEYELEAKSHLKDDRSRLVKQ 1065
Query: 245 MA------------------LLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKR 286
M LL++RIS+ E L++E+ + +A+ E ++ E++
Sbjct: 1066 MEDKVSQLEMELEEERNNSDLLSERISRSREQMEQLRNELLQERAARQDLECDKISLERQ 1125
Query: 287 LQEKMHECAQLGGELDRTRD------EASRA-LQRAHEQTETVRKCLQTTVAELERQLAA 339
++ L G +++ EA A L+ E E R LQ + LER++
Sbjct: 1126 NKDLKSRIIHLEGSYRSSKEGLVVQMEARIAELEDRLESEERDRANLQLSNRRLERKVKE 1185
Query: 340 SRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRR 388
QV + K++L ++K + E+A+ I L++ + L+R
Sbjct: 1186 LVMQVDDEHLSLTDQKDQLSLRLKAMKRQVEEAEEEIDRLESSKKKLQR 1234
Score = 45.2 bits (102), Expect = 4e-04
Identities = 76/390 (19%), Positives = 147/390 (37%), Gaps = 20/390 (5%)
Query: 21 RETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDE-LRTLM 79
R +N+L + L ++ EQ+ +R LK R + + + L
Sbjct: 895 RALENELEAAQGNLSQTTQEQKQLSEKLKEESEQKEQLRRLKNEMENERWHLGKTIEKLQ 954
Query: 80 KEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQEL 139
KE D ++ R L+ Q ++E + + R ++ LE ++ +L + E+
Sbjct: 955 KEMADIVEASRTSTLELQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDEM 1014
Query: 140 APIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCA---REKVVHIFRYLYSLYLVTT 196
+ + L+ Q +A + + E + L EL ++ + + +
Sbjct: 1015 RLMEEELRDYQRAQDEALTKRQLLEQTLKDLEYELEAKSHLKDDRSRLVKQMEDKVSQLE 1074
Query: 197 MTLTQE----DLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRI 252
M L +E DL + S R +Q + LL + ++ E+Q L RI
Sbjct: 1075 MELEEERNNSDLLSERISR-SREQMEQLRNELLQERAARQDLECDKISLERQNKDLKSRI 1133
Query: 253 SQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQL---GGELDRTRDEAS 309
L S +S E L V++ E E RL+ + + A L L+R E
Sbjct: 1134 IHLEG---SYRSSKEGL---VVQMEARIAELEDRLESEERDRANLQLSNRRLERKVKELV 1187
Query: 310 RALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENF 369
+ H + L + ++RQ+ + ++ E +++L+ L QM + E+
Sbjct: 1188 MQVDDEHLSLTDQKDQLSLRLKAMKRQVEEAEEEIDRLESSKKKLQRELEEQMD-MNEHL 1246
Query: 370 EQAQLRILGLQTQVQSLRRTASSTGDGDGE 399
Q QL + +++ L D D +
Sbjct: 1247 -QGQLNSMKKDLRLKKLPSKVLDDMDDDDD 1275
Score = 38.3 bits (85), Expect = 0.049
Identities = 67/352 (19%), Positives = 144/352 (40%), Gaps = 25/352 (7%)
Query: 48 KEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQX 107
KE+ N+ L+ + E EE L+ ++E +L+ + Q + E+ + +
Sbjct: 641 KEERERMRANLEELRSQHNEKVEENSTLQQRLEESEGELRKNLEELFQVKMEREQHQTEI 700
Query: 108 XXXXXXNTRISEQINL----EIQRVKLKFQEKLQELAPIPDLLKATQ----MRLKDAQQA 159
+ + ++++ E + +E LQ + DLL A + + K ++
Sbjct: 701 RDLQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEEQEDLLRKREREL 760
Query: 160 QAIAEHNAEQLA---RELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQ-SEIGRG 215
A+ E+++ +E++ +E+ + L V T E L +S SE +
Sbjct: 761 TALKGALKEEVSSHDQEMDKLKEQYDAELQALRES--VEEATKNVEVLASRSNTSEQDQA 818
Query: 216 NKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIR 275
+ V +L + K + E E+++A L ++I L + K +++ + + +
Sbjct: 819 GTEMRVKLLQEENEKLQGRSEEL---ERRVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQ 875
Query: 276 TEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELER 335
EE+ + K +E + L EL+ + S+ Q + +E +++ +E +
Sbjct: 876 LEEALVHARKEEKEAVSARRALENELEAAQGNLSQTTQEQKQLSEKLKE-----ESEQKE 930
Query: 336 QLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLR 387
QL R + E ER L + K + + E ++ L LQ Q+ +
Sbjct: 931 QL---RRLKNEMENERWHLGKTIEKLQKEMADIVEASRTSTLELQNQLDEYK 979
>BC032762-1|AAH32762.1| 571|Homo sapiens OPTN protein protein.
Length = 571
Score = 48.8 bits (111), Expect = 3e-05
Identities = 47/240 (19%), Positives = 106/240 (44%), Gaps = 11/240 (4%)
Query: 46 GSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRR 105
G+K +E+ V L C RE ++++ L +KE +++ D+ K + +E Q
Sbjct: 215 GAKNYFEHEELTVSQLLLCLREGNQKVERLEVALKEAKERVSDFEKKTSNRSE-IETQTE 273
Query: 106 QXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEH 165
+ E + E++ + L+ +EL L ++ K Q+ E
Sbjct: 274 GSTEKENDEEKGPETVGSEVEALNLQVTSLFKELQEAHTKLSEAELMKKRLQEKCQALER 333
Query: 166 NAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLL 225
+ ELN ++++V+ + L L + + ++ + + +++ E + Q H L
Sbjct: 334 KNSAIPSELN-EKQELVYTNKKL-ELQVESMLSEIKMEQ-AKTEDEKSKLTVLQMTHNKL 390
Query: 226 ----HNSLKPPEKPPERGGDEKQMALLNQRIS--QLAENNISLKS-EIERLKASVIRTEE 278
+N+LK E+ + ++ A+L + +LAE ++ K +++ +K ++ + EE
Sbjct: 391 LQEHNNALKTIEELTRKESEKVDRAVLKELSEKLELAEKALASKQLQMDEMKQTIAKQEE 450
Score = 35.5 bits (78), Expect = 0.35
Identities = 57/301 (18%), Positives = 125/301 (41%), Gaps = 17/301 (5%)
Query: 61 LKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQ 120
L Q +E E +L+ MK N+Q R + L A E+Q+ + + E+
Sbjct: 40 LLQQMKELLTENHQLKEAMK-LNNQAMKGRFEELSAW--TEKQKEERQFFEIQSKEAKER 96
Query: 121 INLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREK 180
+ + + K +E+L +L + ++++ D++ +A AE +QL ++ + +
Sbjct: 97 L-MALSHENEKLKEELGKLKGKSE--RSSEDPTDDSRLPRAEAEQEKDQLRTQVVRLQAE 153
Query: 181 VVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNS--LKPPEKPPER 238
+ + L L + + ED F + + + G + +V + H+ + R
Sbjct: 154 KADLLGIVSELQLKLNSSGSSEDSFVEIR--MAEGEAEGSVKEIKHSPGPTRTVSTGTSR 211
Query: 239 GGDEKQMALLNQR--ISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQ 296
D + ++ +SQL ++ERL+ ++ +E EK+ + Q
Sbjct: 212 SADGAKNYFEHEELTVSQLLLCLREGNQKVERLEVALKEAKERVSDFEKKTSNRSEIETQ 271
Query: 297 LGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKN 356
G ++ DE ++ E + + L V L ++L + ++S AE ++ L+
Sbjct: 272 TEGSTEKENDE-----EKGPETVGSEVEALNLQVTSLFKELQEAHTKLSEAELMKKRLQE 326
Query: 357 R 357
+
Sbjct: 327 K 327
>BC013876-1|AAH13876.1| 577|Homo sapiens optineurin protein.
Length = 577
Score = 48.8 bits (111), Expect = 3e-05
Identities = 47/240 (19%), Positives = 106/240 (44%), Gaps = 11/240 (4%)
Query: 46 GSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRR 105
G+K +E+ V L C RE ++++ L +KE +++ D+ K + +E Q
Sbjct: 221 GAKNYFEHEELTVSQLLLCLREGNQKVERLEVALKEAKERVSDFEKKTSNRSE-IETQTE 279
Query: 106 QXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEH 165
+ E + E++ + L+ +EL L ++ K Q+ E
Sbjct: 280 GSTEKENDEEKGPETVGSEVEALNLQVTSLFKELQEAHTKLSEAELMKKRLQEKCQALER 339
Query: 166 NAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLL 225
+ ELN ++++V+ + L L + + ++ + + +++ E + Q H L
Sbjct: 340 KNSAIPSELN-EKQELVYTNKKL-ELQVESMLSEIKMEQ-AKTEDEKSKLTVLQMTHNKL 396
Query: 226 ----HNSLKPPEKPPERGGDEKQMALLNQRIS--QLAENNISLKS-EIERLKASVIRTEE 278
+N+LK E+ + ++ A+L + +LAE ++ K +++ +K ++ + EE
Sbjct: 397 LQEHNNALKTIEELTRKESEKVDRAVLKELSEKLELAEKALASKQLQMDEMKQTIAKQEE 456
>AY274808-1|AAP42073.1| 1302|Homo sapiens KIAA1749 protein protein.
Length = 1302
Score = 48.8 bits (111), Expect = 3e-05
Identities = 93/395 (23%), Positives = 167/395 (42%), Gaps = 35/395 (8%)
Query: 17 RCQHRETQNKLRELEMKFEGLATHTNMLMGSKEQAF---EQEVNVRALKQCYREAREEID 73
R + RE + EL + L ++L+ +EQ ++E + ALK +E D
Sbjct: 719 RSEDREKGALIEELLQAKQDLQ---DLLIAKEEQEDLLRKRERELTALKGALKEEVSSHD 775
Query: 74 ELRTLMKEQND-QLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKL-- 130
+ +KEQ D +LQ R +A + VE NT +Q E+ RVKL
Sbjct: 776 QEMDKLKEQYDAELQALRESVEEATKNVE------VLASRSNTSEQDQAGTEM-RVKLLQ 828
Query: 131 KFQEKLQELAP-IPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLY 189
+ EKLQ + + + Q +++D + +A A+ ++ E+ E +VH +
Sbjct: 829 EENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQLEEALVHARKEEK 888
Query: 190 SLY-----LVTTMTLTQEDLFG--QSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDE 242
L + Q +L Q Q ++ K+++ LK E ER
Sbjct: 889 EAVSARRALENELEAAQGNLSQTTQEQKQLSEKLKEESEQKEQLRRLKN-EMENERWHLG 947
Query: 243 KQMALLNQRISQLAE----NNISLKSEIERLKASVIR--TEESALANEKRLQ-EKMHECA 295
K + L + ++ + E + + L+++++ K R E EK L+ EK A
Sbjct: 948 KTIEKLQKEMADIVEASRTSTLELQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTA 1007
Query: 296 QLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAAS---RAQVSTAEKERE 352
+ R +E R QRA ++ T R+ L+ T+ +LE +L A + S K+ E
Sbjct: 1008 MKMQDEMRLMEEELRDYQRAQDEALTKRQLLEQTLKDLEYELEAKSHLKDDRSRLVKQME 1067
Query: 353 ELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLR 387
+ ++L +++ N + RI + Q++ LR
Sbjct: 1068 DKVSQLEMELEEERNNSDLLSERISRSREQMEQLR 1102
Score = 46.4 bits (105), Expect = 2e-04
Identities = 92/409 (22%), Positives = 174/409 (42%), Gaps = 43/409 (10%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQ----EVNVRALKQCYREAREEIDE 74
++ + Q + ELE + L L G + +A E E +R L++ AR+E E
Sbjct: 830 ENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQLEEALVHARKEEKE 889
Query: 75 L---RTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKL- 130
R ++ + + Q + Q Q+ + E+ ++ R+ + +E +R L
Sbjct: 890 AVSARRALENELEAAQGNLSQTTQEQKQLSEKLKEESEQKEQLRRLKNE--MENERWHLG 947
Query: 131 KFQEKLQ-ELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRY-L 188
K EKLQ E+A I + + + + L++ Q E N +LA +EK + + L
Sbjct: 948 KTIEKLQKEMADIVEASRTSTLELQN--QLDEYKEKNRRELAEMQRQLKEKTLEAEKSRL 1005
Query: 189 YSLYLVTTMTLTQEDL--FGQSQSEI--GRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQ 244
++ + M L +E+L + ++Q E R +QT+ L + +R KQ
Sbjct: 1006 TAMKMQDEMRLMEEELRDYQRAQDEALTKRQLLEQTLKDLEYELEAKSHLKDDRSRLVKQ 1065
Query: 245 MA------------------LLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKR 286
M LL++RIS+ E L++E+ + +A+ E ++ E++
Sbjct: 1066 MEDKVSQLEMELEEERNNSDLLSERISRSREQMEQLRNELLQERAARQDLECDKISLERQ 1125
Query: 287 LQEKMHECAQLGGELDRTRD------EASRA-LQRAHEQTETVRKCLQTTVAELERQLAA 339
++ L G +++ EA A L+ E E R LQ + LER++
Sbjct: 1126 NKDLKSRIIHLEGSYRSSKEGLVVQMEARIAELEDRLESEERDRANLQLSNRRLERKVKE 1185
Query: 340 SRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRR 388
QV + K++L ++K + E+A+ I L++ + L+R
Sbjct: 1186 LVMQVDDEHLSLTDQKDQLSLRLKAMKRQVEEAEEEIDRLESSKKKLQR 1234
Score = 45.2 bits (102), Expect = 4e-04
Identities = 76/390 (19%), Positives = 147/390 (37%), Gaps = 20/390 (5%)
Query: 21 RETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDE-LRTLM 79
R +N+L + L ++ EQ+ +R LK R + + + L
Sbjct: 895 RALENELEAAQGNLSQTTQEQKQLSEKLKEESEQKEQLRRLKNEMENERWHLGKTIEKLQ 954
Query: 80 KEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQEL 139
KE D ++ R L+ Q ++E + + R ++ LE ++ +L + E+
Sbjct: 955 KEMADIVEASRTSTLELQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDEM 1014
Query: 140 APIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCA---REKVVHIFRYLYSLYLVTT 196
+ + L+ Q +A + + E + L EL ++ + + +
Sbjct: 1015 RLMEEELRDYQRAQDEALTKRQLLEQTLKDLEYELEAKSHLKDDRSRLVKQMEDKVSQLE 1074
Query: 197 MTLTQE----DLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRI 252
M L +E DL + S R +Q + LL + ++ E+Q L RI
Sbjct: 1075 MELEEERNNSDLLSERISR-SREQMEQLRNELLQERAARQDLECDKISLERQNKDLKSRI 1133
Query: 253 SQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQL---GGELDRTRDEAS 309
L S +S E L V++ E E RL+ + + A L L+R E
Sbjct: 1134 IHLEG---SYRSSKEGL---VVQMEARIAELEDRLESEERDRANLQLSNRRLERKVKELV 1187
Query: 310 RALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENF 369
+ H + L + ++RQ+ + ++ E +++L+ L QM + E+
Sbjct: 1188 MQVDDEHLSLTDQKDQLSLRLKAMKRQVEEAEEEIDRLESSKKKLQRELEEQMD-MNEHL 1246
Query: 370 EQAQLRILGLQTQVQSLRRTASSTGDGDGE 399
Q QL + +++ L D D +
Sbjct: 1247 -QGQLNSMKKDLRLKKLPSKVLDDMDDDDD 1275
Score = 38.3 bits (85), Expect = 0.049
Identities = 67/352 (19%), Positives = 144/352 (40%), Gaps = 25/352 (7%)
Query: 48 KEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQX 107
KE+ N+ L+ + E EE L+ ++E +L+ + Q + E+ + +
Sbjct: 641 KEERERMRANLEELRSQHNEKVEENSTLQQRLEESEGELRKNLEELFQVKMEREQHQTEI 700
Query: 108 XXXXXXNTRISEQINL----EIQRVKLKFQEKLQELAPIPDLLKATQ----MRLKDAQQA 159
+ + ++++ E + +E LQ + DLL A + + K ++
Sbjct: 701 RDLQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEEQEDLLRKREREL 760
Query: 160 QAIAEHNAEQLA---RELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQ-SEIGRG 215
A+ E+++ +E++ +E+ + L V T E L +S SE +
Sbjct: 761 TALKGALKEEVSSHDQEMDKLKEQYDAELQALRES--VEEATKNVEVLASRSNTSEQDQA 818
Query: 216 NKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIR 275
+ V +L + K + E E+++A L ++I L + K +++ + + +
Sbjct: 819 GTEMRVKLLQEENEKLQGRSEEL---ERRVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQ 875
Query: 276 TEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELER 335
EE+ + K +E + L EL+ + S+ Q + +E +++ +E +
Sbjct: 876 LEEALVHARKEEKEAVSARRALENELEAAQGNLSQTTQEQKQLSEKLKE-----ESEQKE 930
Query: 336 QLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLR 387
QL R + E ER L + K + + E ++ L LQ Q+ +
Sbjct: 931 QL---RRLKNEMENERWHLGKTIEKLQKEMADIVEASRTSTLELQNQLDEYK 979
>AL589986-1|CAH70024.1| 1943|Homo sapiens trichohyalin protein.
Length = 1943
Score = 48.8 bits (111), Expect = 3e-05
Identities = 67/350 (19%), Positives = 144/350 (41%), Gaps = 14/350 (4%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTL 78
Q R Q RE +++ E L +E+ ++ + + ++ R RE+ + L
Sbjct: 400 QLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERRE-QRLKREQEERRDWL 458
Query: 79 MKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQE 138
+E+ + + + Q ++ EE+RR+ R +Q E Q+++ + +E+ ++
Sbjct: 459 KREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERRE-QQLRREQEERREQ 517
Query: 139 LAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMT 198
+ + Q RL+ QQ + E EQL + RE+ + + L
Sbjct: 518 RLKRQEEEERLQQRLRSEQQLRREQEERREQLLK-----REEEKRLEQERREQRLKREQE 572
Query: 199 LTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAEN 258
++ L + + E + + L LK E + ++ L + +
Sbjct: 573 ERRDQLL-KREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQ 631
Query: 259 NISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQ 318
+ E E + +R E+ E+RL+ + E +L L R +E R + A E+
Sbjct: 632 QLLKSEEQEERRQQQLRREQQE-RREQRLKREEEE-ERLEQRLKREHEEERREQELAEEE 689
Query: 319 TETVRKCLQTTVA----ELERQLAASRAQVSTAEKEREELKNRLHWQMKR 364
E R+ +++ + +LE + A +++V + +++E + R + KR
Sbjct: 690 QEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKR 739
Score = 42.3 bits (95), Expect = 0.003
Identities = 82/375 (21%), Positives = 149/375 (39%), Gaps = 35/375 (9%)
Query: 17 RCQHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELR 76
RCQ RE Q + ++ + KF +EQ ++ R ++ ++ R + E +
Sbjct: 1400 RCQEREQQLR-QDRDRKFR-----------EEEQQLSRQERDRKFREEEQQVRRQERERK 1447
Query: 77 TLMKEQNDQLQDYRVKYLQAQQLV-EEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQE- 134
L +EQ + + +R K+ + +QL+ E + +Q + E+ L Q KF+E
Sbjct: 1448 FLEEEQQLRQERHR-KFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQ 1506
Query: 135 KLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLV 194
+L+ P L+ Q + +Q + + E +QL R+ + + ++ L
Sbjct: 1507 ELRSQEPERKFLEEEQQLHRQQRQRKFLQEE--QQLRRQERGQQRRQDRDRKFREEEQL- 1563
Query: 195 TTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQ 254
++ L Q + R + + E+ R E Q L +R +
Sbjct: 1564 -RQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRR--QEGQQQLRQERDRK 1620
Query: 255 LAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQR 314
E+ L E E + + L E +L+ + E QL + DR E + LQ
Sbjct: 1621 FREDE-QLLQEREEQQLHRQERDRKFLEEEPQLRRQERE-QQLRHDRDRKFREEEQLLQE 1678
Query: 315 AHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENF-EQAQ 373
EQ Q E +R+ Q+ E+ER+ L+ + + L F E+ Q
Sbjct: 1679 GEEQ--------QLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQ 1730
Query: 374 LRILGLQTQVQSLRR 388
LR +T+ + LRR
Sbjct: 1731 LR---QETEQEQLRR 1742
Score = 41.1 bits (92), Expect = 0.007
Identities = 71/364 (19%), Positives = 145/364 (39%), Gaps = 11/364 (3%)
Query: 17 RCQHRETQNKLRELEMKFEGLAT-HTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDEL 75
+ Q E Q + REL+ + E L L +++ +Q+ +R +Q R+ EE E
Sbjct: 259 KLQEEEPQRQ-RELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQ 317
Query: 76 RTLMKEQNDQLQDYRVKYLQAQQLVEEQRR-QXXXXXXXNTRISEQINLEIQRVKLKFQE 134
+ +EQ ++ + + Q + +E+RR Q R +Q+ E + + + Q
Sbjct: 318 QEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQL 377
Query: 135 KLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLV 194
+ ++ L+ Q ++ Q + +QL RE RE+ + +
Sbjct: 378 RREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQK 437
Query: 195 TTMTLTQEDL-FGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMAL-LNQRI 252
++ L Q + +++T + ++ E E+ + L +R
Sbjct: 438 HEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERR 497
Query: 253 SQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRAL 312
Q L+ E E + ++ +E E+RLQ+++ QL E + R++ +
Sbjct: 498 EQQERREQQLRREQEERREQRLKRQE----EEERLQQRLRSEQQLRREQEERREQLLKRE 553
Query: 313 QRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKR-LTENFEQ 371
+ + E + L+ E QL R + ++ + E + RL ++KR E EQ
Sbjct: 554 EEKRLEQERREQRLKREQEERRDQL-LKREEERRQQRLKREQEERLEQRLKREEVERLEQ 612
Query: 372 AQLR 375
+ R
Sbjct: 613 EERR 616
Score = 39.5 bits (88), Expect = 0.021
Identities = 81/380 (21%), Positives = 157/380 (41%), Gaps = 18/380 (4%)
Query: 22 ETQNKLREL-EMKFEGLATHTNMLMGSKEQAF--EQEVNVRALKQCYREAREEIDE---- 74
E Q + REL E++ +G +++ F E+E R + R+ E++ E
Sbjct: 207 EEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQ 266
Query: 75 LRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQE 134
+ ++E+ +QL+ + L+ ++ EEQ++Q R E+ E Q + + QE
Sbjct: 267 RQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQE 326
Query: 135 K--LQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLAREL-NCAREKVVHIFRYL-YS 190
+ QE L + + R + + + E +QL RE RE+ + + L
Sbjct: 327 RREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRRE 386
Query: 191 LYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQ 250
L L +E + Q ++ R + + L E+ ER + + Q
Sbjct: 387 QQLRREQQLRREQQLRREQ-QLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQ 445
Query: 251 RISQLAENNIS-LKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDE-A 308
R+ + E LK E E + R ++ +++ +E+ +L E R + E
Sbjct: 446 RLKREQEERRDWLKREEETERHEQERRKQQLKRDQE--EERRERWLKLEEEERREQQERR 503
Query: 309 SRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTEN 368
+ L+R E+ R Q L+++L + + E+ RE+L R + KRL +
Sbjct: 504 EQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKR--EEEKRLEQE 561
Query: 369 FEQAQLRILGLQTQVQSLRR 388
+ +L+ + + Q L+R
Sbjct: 562 RREQRLKREQEERRDQLLKR 581
Score = 38.3 bits (85), Expect = 0.049
Identities = 69/362 (19%), Positives = 141/362 (38%), Gaps = 19/362 (5%)
Query: 21 RETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMK 80
RE + L+E E + + ++Q QE + + +Q E R + E + L +
Sbjct: 1464 REEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQ---ELRSQEPERKFLEE 1520
Query: 81 EQNDQLQDYRVKYLQAQQLVEEQRR--QXXXXXXXNTRISEQINLEIQRVKLKFQEKLQE 138
EQ Q + K+LQ +Q + Q R Q R EQ+ E + +L QE+ ++
Sbjct: 1521 EQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRK 1580
Query: 139 LAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMT 198
++ + K + Q + +Q R+ R++ L +
Sbjct: 1581 FRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQ---ERDRKFREDEQLLQEREEQQLH 1637
Query: 199 LTQED-LFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAE 257
+ D F + + ++ R ++Q + + E+ + G E+Q +R + E
Sbjct: 1638 RQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEG--EEQQLRRQERDRKFRE 1695
Query: 258 NNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHE 317
L+ + K EE L ++ L+ K E QL E ++ + ++ E
Sbjct: 1696 EEQQLRRQERERK---FLQEEQQLRRQE-LERKFREEEQLRQETEQEQLRRQERYRKILE 1751
Query: 318 QTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELK----NRLHWQMKRLTENFEQAQ 373
+ + + + + ER + E+E ++L+ +R + ++L + E+ Q
Sbjct: 1752 EEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQ 1811
Query: 374 LR 375
LR
Sbjct: 1812 LR 1813
Score = 36.7 bits (81), Expect = 0.15
Identities = 69/327 (21%), Positives = 136/327 (41%), Gaps = 20/327 (6%)
Query: 67 EAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEE---QRRQXXXXXXXNTRISEQINL 123
E R D +L++++ + +D R + +QL EE +RRQ E+ +
Sbjct: 98 EKRARCDGKESLLQDRRQE-EDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSE 156
Query: 124 EIQRVKLKFQEKL-QELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVV 182
+ +R++ + +++ +EL + + R + +Q Q+ H E+ E R +++
Sbjct: 157 KQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELL 216
Query: 183 HIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDE 242
+ R ++D Q + E K +TV L K E+ P+R +
Sbjct: 217 ELRRK--GREEKQQQRRERQDRVFQEEEE-KEWRKRETV--LRKEEEKLQEEEPQR---Q 268
Query: 243 KQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALAN-EKRLQEKMHECAQLGGEL 301
+++ +++ +L + + + E + +R E+ E+ +E+ E + +
Sbjct: 269 RELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERRE--QQE 326
Query: 302 DRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQ 361
R + E R Q EQ E + L+ E R+ R Q E+ER E + R Q
Sbjct: 327 RREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQ----EEERREQQLRREQQ 382
Query: 362 MKRLTENFEQAQLRILGLQTQVQSLRR 388
++R + + QLR + Q LRR
Sbjct: 383 LRREQQLRREQQLRREQQLRREQQLRR 409
Score = 35.9 bits (79), Expect = 0.26
Identities = 76/375 (20%), Positives = 153/375 (40%), Gaps = 30/375 (8%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTL 78
+ RE + + +E + KF +L +EQ ++ R ++ E R + + L
Sbjct: 1323 EEREEKRRRQETDRKFR---EEEQLLQEREEQPLRRQERDRKFRE--EELRHQEQGRKFL 1377
Query: 79 MKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRI-SEQINLEIQRVKLKFQEKLQ 137
+EQ + Q+ K+L+ +Q + Q R+ + + E+ L Q KF+E+ Q
Sbjct: 1378 EEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQ 1437
Query: 138 EL----APIPDLLKATQMR----LKDAQQAQAIAEHNAEQLARELNCAR--EKVVHIFRY 187
++ L + Q+R K ++ Q + E +QL R+ + E+ + R
Sbjct: 1438 QVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQ 1497
Query: 188 LYSLYLVTTMTLTQED--LFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQM 245
+QE F + + ++ R + Q + L+ E+ +R D +
Sbjct: 1498 ERDRKFREQELRSQEPERKFLEEEQQLHRQQR-QRKFLQEEQQLRRQERGQQRRQDRDRK 1556
Query: 246 ALLNQRISQLAENNISLKSEIE---RLKASVIRTEESALANEKRLQEKMHECAQLGGELD 302
+++ Q E + E + RL+ +R +E E++ E + + G+
Sbjct: 1557 FREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQE----QERKFMEDEQQLRRQEGQ-Q 1611
Query: 303 RTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKERE--ELKNRLHW 360
+ R E R R EQ R+ Q E +R+ Q+ E+E++ ++R
Sbjct: 1612 QLRQERDRKF-REDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFR 1670
Query: 361 QMKRLTENFEQAQLR 375
+ ++L + E+ QLR
Sbjct: 1671 EEEQLLQEGEEQQLR 1685
Score = 33.1 bits (72), Expect = 1.8
Identities = 28/121 (23%), Positives = 56/121 (46%), Gaps = 6/121 (4%)
Query: 17 RCQHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELR 76
R Q RE Q + + + KF +L +EQ ++ R ++ ++ R + E +
Sbjct: 1653 RRQEREQQLR-HDRDRKFR---EEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERK 1708
Query: 77 TLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRI--SEQINLEIQRVKLKFQE 134
L +EQ + Q+ K+ + +QL +E ++ +I EQ+ E + +L+ QE
Sbjct: 1709 FLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQE 1768
Query: 135 K 135
+
Sbjct: 1769 R 1769
>AF420373-1|AAL76329.1| 577|Homo sapiens optineurin isoform 3
protein.
Length = 577
Score = 48.8 bits (111), Expect = 3e-05
Identities = 47/240 (19%), Positives = 106/240 (44%), Gaps = 11/240 (4%)
Query: 46 GSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRR 105
G+K +E+ V L C RE ++++ L +KE +++ D+ K + +E Q
Sbjct: 221 GAKNYFEHEELTVSQLLLCLREGNQKVERLEVALKEAKERVSDFEKKTSNRSE-IETQTE 279
Query: 106 QXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEH 165
+ E + E++ + L+ +EL L ++ K Q+ E
Sbjct: 280 GSTEKENDEEKGPETVGSEVEALNLQVTSLFKELQEAHTKLSEAELMKKRLQEKCQALER 339
Query: 166 NAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLL 225
+ ELN ++++V+ + L L + + ++ + + +++ E + Q H L
Sbjct: 340 KNSAIPSELN-EKQELVYTNKKL-ELQVESMLSEIKMEQ-AKTEDEKSKLTVLQMTHNKL 396
Query: 226 ----HNSLKPPEKPPERGGDEKQMALLNQRIS--QLAENNISLKS-EIERLKASVIRTEE 278
+N+LK E+ + ++ A+L + +LAE ++ K +++ +K ++ + EE
Sbjct: 397 LQEHNNALKTIEELTRKESEKVDRAVLKELSEKLELAEKALASKQLQMDEMKQTIAKQEE 456
>AF420372-1|AAL76328.1| 577|Homo sapiens optineurin isoform 2
protein.
Length = 577
Score = 48.8 bits (111), Expect = 3e-05
Identities = 47/240 (19%), Positives = 106/240 (44%), Gaps = 11/240 (4%)
Query: 46 GSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRR 105
G+K +E+ V L C RE ++++ L +KE +++ D+ K + +E Q
Sbjct: 221 GAKNYFEHEELTVSQLLLCLREGNQKVERLEVALKEAKERVSDFEKKTSNRSE-IETQTE 279
Query: 106 QXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEH 165
+ E + E++ + L+ +EL L ++ K Q+ E
Sbjct: 280 GSTEKENDEEKGPETVGSEVEALNLQVTSLFKELQEAHTKLSEAELMKKRLQEKCQALER 339
Query: 166 NAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLL 225
+ ELN ++++V+ + L L + + ++ + + +++ E + Q H L
Sbjct: 340 KNSAIPSELN-EKQELVYTNKKL-ELQVESMLSEIKMEQ-AKTEDEKSKLTVLQMTHNKL 396
Query: 226 ----HNSLKPPEKPPERGGDEKQMALLNQRIS--QLAENNISLKS-EIERLKASVIRTEE 278
+N+LK E+ + ++ A+L + +LAE ++ K +++ +K ++ + EE
Sbjct: 397 LQEHNNALKTIEELTRKESEKVDRAVLKELSEKLELAEKALASKQLQMDEMKQTIAKQEE 456
>AF420371-1|AAL76327.1| 577|Homo sapiens optineurin isoform 1
protein.
Length = 577
Score = 48.8 bits (111), Expect = 3e-05
Identities = 47/240 (19%), Positives = 106/240 (44%), Gaps = 11/240 (4%)
Query: 46 GSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRR 105
G+K +E+ V L C RE ++++ L +KE +++ D+ K + +E Q
Sbjct: 221 GAKNYFEHEELTVSQLLLCLREGNQKVERLEVALKEAKERVSDFEKKTSNRSE-IETQTE 279
Query: 106 QXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEH 165
+ E + E++ + L+ +EL L ++ K Q+ E
Sbjct: 280 GSTEKENDEEKGPETVGSEVEALNLQVTSLFKELQEAHTKLSEAELMKKRLQEKCQALER 339
Query: 166 NAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLL 225
+ ELN ++++V+ + L L + + ++ + + +++ E + Q H L
Sbjct: 340 KNSAIPSELN-EKQELVYTNKKL-ELQVESMLSEIKMEQ-AKTEDEKSKLTVLQMTHNKL 396
Query: 226 ----HNSLKPPEKPPERGGDEKQMALLNQRIS--QLAENNISLKS-EIERLKASVIRTEE 278
+N+LK E+ + ++ A+L + +LAE ++ K +++ +K ++ + EE
Sbjct: 397 LQEHNNALKTIEELTRKESEKVDRAVLKELSEKLELAEKALASKQLQMDEMKQTIAKQEE 456
>AF111782-1|AAD29948.1| 1938|Homo sapiens myosin heavy chain protein.
Length = 1938
Score = 48.8 bits (111), Expect = 3e-05
Identities = 75/332 (22%), Positives = 141/332 (42%), Gaps = 37/332 (11%)
Query: 45 MGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQND---QLQDYRVKYLQAQQ--- 98
M + ++ FE+ A + R+ EE ++ +L++E+ND Q+Q + A++
Sbjct: 853 MATMKEDFERTKEELARSEARRKELEE--KMVSLLQEKNDLQLQVQSETENLMDAEERCE 910
Query: 99 -LVEEQRRQXXXXXXXNTRISEQ--INLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKD 155
L++ + R+ E+ +N E+ K ++K L D L+ T +++
Sbjct: 911 GLIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLELTLTKVEK 970
Query: 156 AQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRG 215
+ A E+ + L+ E+ E + + + SL TL +DL Q E +
Sbjct: 971 EKHA---TENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTL--DDL----QVEEDKV 1021
Query: 216 NKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIR 275
N ++ L E E+ EK++ +R + E ++ + E S++
Sbjct: 1022 NGLIKINAKLEQQTDDLEGSLEQ---EKKLRADLERAKRKLEGDLKMSQE------SIMD 1072
Query: 276 TEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELER 335
E E++L++K E +QL +D DE +LQ + E LQ + ELE
Sbjct: 1073 LENEKQQIEEKLKKKEFELSQLQARID---DEQVHSLQFQKKIKE-----LQARIEELEE 1124
Query: 336 QLAASRAQVSTAEKEREELKNRLHWQMKRLTE 367
++ A + EK+R +L L +RL E
Sbjct: 1125 EIEAEHTLRAKIEKQRSDLARELEEISERLEE 1156
Score = 48.4 bits (110), Expect = 5e-05
Identities = 68/333 (20%), Positives = 133/333 (39%), Gaps = 15/333 (4%)
Query: 49 EQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXX 108
EQ E N++ ++ + +E +L+ ++E L+ K L+ Q + + + +
Sbjct: 1518 EQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQLELSQVKSELD 1577
Query: 109 XXXXXNTRISEQINLEIQRVKLKFQEKLQ-ELAPIPDLLKATQMRLKDAQQAQAIAEHNA 167
EQ+ QR Q L E+ D L+ + D + + H+
Sbjct: 1578 RKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKKKMEGDLNEMEIQLGHSN 1637
Query: 168 EQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHN 227
Q+A R + L+L + + EDL + Q I + L
Sbjct: 1638 RQMAETQRHLRTVQGQLKDS--QLHLDDALR-SNEDL--KEQLAIVERRNGLLLEELEEM 1692
Query: 228 SLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTE---ESALANE 284
+ + R E+++ + R+ L N SL + ++L+A + + + E+++
Sbjct: 1693 KVALEQTERTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQCQAEVENSIQES 1752
Query: 285 KRLQEK----MHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELER-QLAA 339
+ +EK + + A + EL + +D ++ L+R + E K LQ + E E+ L
Sbjct: 1753 RNAEEKAKKAITDAAMMAEELKKEQDTSAH-LERMKKNLEQTVKDLQHRLDEAEQLALKG 1811
Query: 340 SRAQVSTAEKEREELKNRLHWQMKRLTENFEQA 372
+ Q+ E EL+N L + KR E + A
Sbjct: 1812 GKKQIQKLENRVRELENELDVEQKRGAEALKGA 1844
Score = 39.9 bits (89), Expect = 0.016
Identities = 83/383 (21%), Positives = 160/383 (41%), Gaps = 47/383 (12%)
Query: 22 ETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKE 81
E+Q +L + + L+T + + E+ +Q + L++ + +EEI +L + E
Sbjct: 1466 ESQAELEAAQKESRSLSTELFKMRNAYEEVVDQ---LETLRRENKNLQEEISDLTEQIAE 1522
Query: 82 QNDQLQDY-RVKYLQAQQLVEEQRRQXXXXXXXNTRISE--QINLEIQRVKLKFQEKLQE 138
LQ+ + K L Q+ + Q S+ ++ LE+ +VK + K+ E
Sbjct: 1523 TGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQLELSQVKSELDRKVIE 1582
Query: 139 LAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMT 198
+ LK R +A Q+ AE + A L E ++ + M
Sbjct: 1583 KDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKKKMEGDLNEMEIQLG-HSNRQMA 1641
Query: 199 LTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAEN 258
TQ L Q ++ KD +H L ++L+ E E Q+A++ +R L E
Sbjct: 1642 ETQRHL-RTVQGQL----KDSQLH--LDDALRSNEDLKE------QLAIVERRNGLLLE- 1687
Query: 259 NISLKSEIERLKASVIRTEESALANEKRLQEK--------------MHECAQLGGELDRT 304
E+E +K ++ +TE + +E+ L + ++ +L ++ +
Sbjct: 1688 ------ELEEMKVALEQTERTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQC 1741
Query: 305 RDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKR 364
+ E ++Q + E +K + T A + +L + Q ++A ER +K L +K
Sbjct: 1742 QAEVENSIQESRNAEEKAKKAI-TDAAMMAEEL--KKEQDTSAHLER--MKKNLEQTVKD 1796
Query: 365 LTENFEQA-QLRILGLQTQVQSL 386
L ++A QL + G + Q+Q L
Sbjct: 1797 LQHRLDEAEQLALKGGKKQIQKL 1819
Score = 37.9 bits (84), Expect = 0.065
Identities = 69/354 (19%), Positives = 151/354 (42%), Gaps = 35/354 (9%)
Query: 26 KLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQ 85
+L EL+ + E T M Q+ + ++ L++ Y E +E EL+ + + N +
Sbjct: 1315 QLEELKRQMEE-ETKAKNAMAHALQSSRHDCDL--LREQYEEEQEAKAELQRALSKANSE 1371
Query: 86 LQDYRVKY----LQAQQLVEEQRRQXXXXXXXNTRISEQIN---LEIQRVKLKFQEKLQE 138
+ ++ KY +Q + +EE +++ +E N +++ K + Q ++++
Sbjct: 1372 VAQWKTKYETDAIQRTEELEEAKKKLAQRLQEAEEKTETANSKCASLEKTKQRLQGEVED 1431
Query: 139 LAPIPDLLKA-TQMRLKDAQQA---QAIAE--HNAEQLARELNCAREKVVHIFRYLYSLY 192
L + DL ++ T D +Q + +AE ++ EL A+++ + L+
Sbjct: 1432 L--MRDLERSHTACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFK-- 1487
Query: 193 LVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVL-LHNSLKPPEKPPERGGDEKQMALLNQR 251
M E++ Q ++ + R NK+ + L + K + EK L+ Q
Sbjct: 1488 ----MRNAYEEVVDQLET-LRRENKNLQEEISDLTEQIAETGKNLQEA--EKTKKLVEQE 1540
Query: 252 ISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRA 311
S L ++ +E ++ ++R + + L K+ E + +L R A+ A
Sbjct: 1541 KSDLQVALEEVEGSLEHEESKILRVQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEA 1600
Query: 312 LQ-------RAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRL 358
LQ R+ ++K ++ + E+E QL S Q++ ++ ++ +L
Sbjct: 1601 LQSVLDAEIRSRNDALRLKKKMEGDLNEMEIQLGHSNRQMAETQRHLRTVQGQL 1654
Score = 37.9 bits (84), Expect = 0.065
Identities = 31/144 (21%), Positives = 70/144 (48%), Gaps = 10/144 (6%)
Query: 261 SLKSEIERLKASVIRTEESAL-ANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQT 319
+L+ ++ L+ + E+ AL +K++Q+ + +L ELD + + AL+ AH+
Sbjct: 1789 NLEQTVKDLQHRLDEAEQLALKGGKKQIQKLENRVRELENELDVEQKRGAEALKGAHKYE 1848
Query: 320 ETVRKCL------QTTVAELERQLAASRAQVSTAEKEREELKNRLHWQM---KRLTENFE 370
V++ + + L+ + +A+V + +++ EE + + + Q+ +R+ E
Sbjct: 1849 RKVKEMTYQAEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQANTQLSRCRRVQHELE 1908
Query: 371 QAQLRILGLQTQVQSLRRTASSTG 394
+A R ++QV LR + G
Sbjct: 1909 EAAERADIAESQVNKLRAKSRDVG 1932
Score = 33.5 bits (73), Expect = 1.4
Identities = 63/324 (19%), Positives = 124/324 (38%), Gaps = 28/324 (8%)
Query: 84 DQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIP 143
DQ + + K Q QL+ + Q N +S ++ E + + + + Q L
Sbjct: 1258 DQFSEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVE-EKESLISQLTKSKQALTQQL 1316
Query: 144 DLLKATQMRLKDAQQAQAIA----EHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTL 199
+ LK A+ A A A H+ + L + +E + R L
Sbjct: 1317 EELKRQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWK 1376
Query: 200 TQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENN 259
T+ + I R + + L L+ E+ E + A L + +L
Sbjct: 1377 TKYE-----TDAIQRTEELEEAKKKLAQRLQEAEEKTETA--NSKCASLEKTKQRLQGEV 1429
Query: 260 ISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEA----------S 309
L ++ER + ++ +K L E + + EL+ + E+
Sbjct: 1430 EDLMRDLERSHTACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMR 1489
Query: 310 RALQRAHEQTETVR---KCLQTTVAELERQLAASRAQVSTAEKER---EELKNRLHWQMK 363
A + +Q ET+R K LQ +++L Q+A + + AEK + E+ K+ L ++
Sbjct: 1490 NAYEEVVDQLETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALE 1549
Query: 364 RLTENFEQAQLRILGLQTQVQSLR 387
+ + E + +IL +Q ++ ++
Sbjct: 1550 EVEGSLEHEESKILRVQLELSQVK 1573
Score = 32.3 bits (70), Expect = 3.2
Identities = 31/121 (25%), Positives = 55/121 (45%), Gaps = 7/121 (5%)
Query: 242 EKQMALLNQRISQLAEN---NISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLG 298
+K++ L RI +L E +L+++IE+ ++ + R E + ++
Sbjct: 1109 QKKIKELQARIEELEEEIEAEHTLRAKIEKQRSDLARELEEISERLEEASGATSAQIEMN 1168
Query: 299 GELDRTRDEASRALQRA---HEQTE-TVRKCLQTTVAELERQLAASRAQVSTAEKEREEL 354
+ + + R L+ A HE T T+RK +VAEL Q+ + EKE+ EL
Sbjct: 1169 KKREAEFQKMRRDLEEATLQHEATAATLRKKQADSVAELGEQIDNLQRVKQKLEKEKSEL 1228
Query: 355 K 355
K
Sbjct: 1229 K 1229
>AB053471-1|BAC54110.1| 1116|Homo sapiens ELKS epsilon protein.
Length = 1116
Score = 48.8 bits (111), Expect = 3e-05
Identities = 86/398 (21%), Positives = 168/398 (42%), Gaps = 42/398 (10%)
Query: 21 RETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMK 80
+E K EL L T TN SK+ + ++ A +Q + E+D LR ++
Sbjct: 473 QELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLE 532
Query: 81 EQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRI---SEQINL---EIQRVKLKFQE 134
E+ L K Q Q + EE+ Q + ++N+ +I+ ++ + ++
Sbjct: 533 EKETMLNK---KTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRD 589
Query: 135 KLQELAPIPDLLKA-------TQMRLKDAQQAQAIAEHNAEQLARELN-CAREKVVHIFR 186
K ++++ + + +K+ T L ++A A E E+L + + REK I
Sbjct: 590 KEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDN 649
Query: 187 YLYSLY-LVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQM 245
Y L L ++L Q DL S+ E + + L + LK + ++
Sbjct: 650 YKKDLKDLKEKVSLLQGDL---SEKEASLLDLKEHASSLASSGLK----------KDSRL 696
Query: 246 ALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQ-LGGELDRT 304
L + Q E + ++S+++ + E+AL E R +M + Q L E+ R
Sbjct: 697 KTLEIALEQKKEECLKMESQLK-------KAHEAAL--EARASPEMSDRIQHLEREITRY 747
Query: 305 RDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKR 364
+DE+S+A E +++ ++ + ++++A QV K+ LK++ + K+
Sbjct: 748 KDESSKAQAEVDRLLEILKE-VENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKK 806
Query: 365 LTENFEQAQLRILGLQTQVQSLRRTASSTGDGDGENQE 402
+ E+A+ R L Q L+ + D E +E
Sbjct: 807 SAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEE 844
Score = 31.1 bits (67), Expect = 7.4
Identities = 62/348 (17%), Positives = 143/348 (41%), Gaps = 37/348 (10%)
Query: 24 QNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQN 83
Q L E E L H + L S +++ ++ L+ + +EE ++ + +K+ +
Sbjct: 665 QGDLSEKEASLLDLKEHASSLASS---GLKKDSRLKTLEIALEQKKEECLKMESQLKKAH 721
Query: 84 DQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQIN--LEI-QRVKLKFQEKLQELA 140
+ + R + + ++ R+ +++ +++ LEI + V+ + +K +++A
Sbjct: 722 EAALEARASPEMSDR-IQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIA 780
Query: 141 PIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLT 200
+ +K ++ + + + + + + Q+ E + + + L +L
Sbjct: 781 ELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQD-------SLR 833
Query: 201 QEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNI 260
++D + E R ++V + + ++ R EKQ+ L + ++
Sbjct: 834 KKDDRIEELEEALR----ESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKV----- 884
Query: 261 SLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTE 320
K E+E +KA + T++S E L A+ L+ + AL A + +
Sbjct: 885 --KQELESMKAKLSSTQQSLAEKETHLTNLR---AERRKHLEEVLEMKQEALLAAISEKD 939
Query: 321 TVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTEN 368
+A LE + + Q A +RE K+RL Q+K+ T+N
Sbjct: 940 -------ANIALLELSSSKKKTQEEVAALKRE--KDRLVQQLKQQTQN 978
Score = 31.1 bits (67), Expect = 7.4
Identities = 30/155 (19%), Positives = 68/155 (43%), Gaps = 9/155 (5%)
Query: 21 RETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMK 80
++ Q+ LR+ + + E L L S + E+E+ + + A ++++EL M+
Sbjct: 826 QQLQDSLRKKDDRIEELE---EALRESVQITAEREMVLAQEESARTNAEKQVEELLMAME 882
Query: 81 EQNDQLQDYRVKYLQAQQ-LVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQEL 139
+ +L+ + K QQ L E++ + E + ++ + + EK +
Sbjct: 883 KVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANI 942
Query: 140 APIPDLLKATQMRLKDAQQAQAIAEHNAEQLAREL 174
A LL+ + + K Q+ A + ++L ++L
Sbjct: 943 A----LLELSSSK-KKTQEEVAALKREKDRLVQQL 972
>AB053470-1|BAC54109.1| 1088|Homo sapiens ELKS delta protein.
Length = 1088
Score = 48.8 bits (111), Expect = 3e-05
Identities = 86/398 (21%), Positives = 168/398 (42%), Gaps = 42/398 (10%)
Query: 21 RETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMK 80
+E K EL L T TN SK+ + ++ A +Q + E+D LR ++
Sbjct: 445 QELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLE 504
Query: 81 EQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRI---SEQINL---EIQRVKLKFQE 134
E+ L K Q Q + EE+ Q + ++N+ +I+ ++ + ++
Sbjct: 505 EKETMLNK---KTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRD 561
Query: 135 KLQELAPIPDLLKA-------TQMRLKDAQQAQAIAEHNAEQLARELN-CAREKVVHIFR 186
K ++++ + + +K+ T L ++A A E E+L + + REK I
Sbjct: 562 KEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDN 621
Query: 187 YLYSLY-LVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQM 245
Y L L ++L Q DL S+ E + + L + LK + ++
Sbjct: 622 YKKDLKDLKEKVSLLQGDL---SEKEASLLDLKEHASSLASSGLK----------KDSRL 668
Query: 246 ALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQ-LGGELDRT 304
L + Q E + ++S+++ + E+AL E R +M + Q L E+ R
Sbjct: 669 KTLEIALEQKKEECLKMESQLK-------KAHEAAL--EARASPEMSDRIQHLEREITRY 719
Query: 305 RDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKR 364
+DE+S+A E +++ ++ + ++++A QV K+ LK++ + K+
Sbjct: 720 KDESSKAQAEVDRLLEILKE-VENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKK 778
Query: 365 LTENFEQAQLRILGLQTQVQSLRRTASSTGDGDGENQE 402
+ E+A+ R L Q L+ + D E +E
Sbjct: 779 SAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEE 816
Score = 31.1 bits (67), Expect = 7.4
Identities = 62/348 (17%), Positives = 143/348 (41%), Gaps = 37/348 (10%)
Query: 24 QNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQN 83
Q L E E L H + L S +++ ++ L+ + +EE ++ + +K+ +
Sbjct: 637 QGDLSEKEASLLDLKEHASSLASS---GLKKDSRLKTLEIALEQKKEECLKMESQLKKAH 693
Query: 84 DQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQIN--LEI-QRVKLKFQEKLQELA 140
+ + R + + ++ R+ +++ +++ LEI + V+ + +K +++A
Sbjct: 694 EAALEARASPEMSDR-IQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIA 752
Query: 141 PIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLT 200
+ +K ++ + + + + + + Q+ E + + + L +L
Sbjct: 753 ELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQD-------SLR 805
Query: 201 QEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNI 260
++D + E R ++V + + ++ R EKQ+ L + ++
Sbjct: 806 KKDDRIEELEEALR----ESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKV----- 856
Query: 261 SLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTE 320
K E+E +KA + T++S E L A+ L+ + AL A + +
Sbjct: 857 --KQELESMKAKLSSTQQSLAEKETHLTNLR---AERRKHLEEVLEMKQEALLAAISEKD 911
Query: 321 TVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTEN 368
+A LE + + Q A +RE K+RL Q+K+ T+N
Sbjct: 912 -------ANIALLELSSSKKKTQEEVAALKRE--KDRLVQQLKQQTQN 950
Score = 31.1 bits (67), Expect = 7.4
Identities = 30/155 (19%), Positives = 68/155 (43%), Gaps = 9/155 (5%)
Query: 21 RETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMK 80
++ Q+ LR+ + + E L L S + E+E+ + + A ++++EL M+
Sbjct: 798 QQLQDSLRKKDDRIEELE---EALRESVQITAEREMVLAQEESARTNAEKQVEELLMAME 854
Query: 81 EQNDQLQDYRVKYLQAQQ-LVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQEL 139
+ +L+ + K QQ L E++ + E + ++ + + EK +
Sbjct: 855 KVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANI 914
Query: 140 APIPDLLKATQMRLKDAQQAQAIAEHNAEQLAREL 174
A LL+ + + K Q+ A + ++L ++L
Sbjct: 915 A----LLELSSSK-KKTQEEVAALKREKDRLVQQL 944
>AB053468-1|BAC54107.1| 992|Homo sapiens ELKS beta protein.
Length = 992
Score = 48.8 bits (111), Expect = 3e-05
Identities = 84/397 (21%), Positives = 162/397 (40%), Gaps = 36/397 (9%)
Query: 21 RETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMK 80
+E K EL L T TN SK+ + ++ A +Q + E+D LR ++
Sbjct: 445 QELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLE 504
Query: 81 EQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRI---SEQINL---EIQRVKLKFQE 134
E+ L K Q Q + EE+ Q + ++N+ +I+ ++ + ++
Sbjct: 505 EKETMLNK---KTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRD 561
Query: 135 KLQELAPIPDLLKA-------TQMRLKDAQQAQAIAEHNAEQLARELN-CAREKVVHIFR 186
K ++++ + + +K+ T L ++A A E E+L + + REK I
Sbjct: 562 KEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDN 621
Query: 187 YLYSLY-LVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQM 245
Y L L ++L Q DL S+ E + + L + LK + ++
Sbjct: 622 YKKDLKDLKEKVSLLQGDL---SEKEASLLDLKEHASSLASSGLK----------KDSRL 668
Query: 246 ALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTR 305
L + Q E + ++S++++ + + S ++ R+Q E + E + +
Sbjct: 669 KTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSD-RIQHLEREITRYKDESSKAQ 727
Query: 306 DEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRL 365
E R L+ E E + +AELE + + QV K+ LK++ + K+
Sbjct: 728 AEVDRLLEILKE-VENEKNDKDKKIAELE---SLTSRQVKDQNKKVANLKHKEQVEKKKS 783
Query: 366 TENFEQAQLRILGLQTQVQSLRRTASSTGDGDGENQE 402
+ E+A+ R L Q L+ + D E +E
Sbjct: 784 AQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEE 820
Score = 34.7 bits (76), Expect = 0.60
Identities = 64/345 (18%), Positives = 137/345 (39%), Gaps = 27/345 (7%)
Query: 24 QNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQN 83
Q L E E L H + L S +++ ++ L+ + +EE ++ + +K+ +
Sbjct: 637 QGDLSEKEASLLDLKEHASSLASS---GLKKDSRLKTLEIALEQKKEECLKMESQLKKAH 693
Query: 84 DQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIP 143
+ + R + + ++ R+ +++ +++ ++ +K EK + I
Sbjct: 694 EAALEARASPEMSDR-IQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIA 752
Query: 144 DLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQED 203
+L T ++KD + A +H + ++ E+ L +L ++D
Sbjct: 753 ELESLTSRQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKD 812
Query: 204 LFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLK 263
+ E R ++V + + ++ R EKQ+ L + ++ K
Sbjct: 813 DRIEELEEALR----ESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKV-------K 861
Query: 264 SEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVR 323
E+E +KA + T++S E L A+ L+ + AL A + +
Sbjct: 862 QELESMKAKLSSTQQSLAEKETHLTNLR---AERRKHLEEVLEMKQEALLAAISEKD--- 915
Query: 324 KCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTEN 368
+A LE + + Q A +RE K+RL Q+K+ T+N
Sbjct: 916 ----ANIALLELSSSKKKTQEEVAALKRE--KDRLVQQLKQQTQN 954
Score = 31.1 bits (67), Expect = 7.4
Identities = 30/155 (19%), Positives = 68/155 (43%), Gaps = 9/155 (5%)
Query: 21 RETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMK 80
++ Q+ LR+ + + E L L S + E+E+ + + A ++++EL M+
Sbjct: 802 QQLQDSLRKKDDRIEELE---EALRESVQITAEREMVLAQEESARTNAEKQVEELLMAME 858
Query: 81 EQNDQLQDYRVKYLQAQQ-LVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQEL 139
+ +L+ + K QQ L E++ + E + ++ + + EK +
Sbjct: 859 KVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANI 918
Query: 140 APIPDLLKATQMRLKDAQQAQAIAEHNAEQLAREL 174
A LL+ + + K Q+ A + ++L ++L
Sbjct: 919 A----LLELSSSK-KKTQEEVAALKREKDRLVQQL 948
>AB029004-1|BAA83033.2| 1003|Homo sapiens KIAA1081 protein protein.
Length = 1003
Score = 48.8 bits (111), Expect = 3e-05
Identities = 84/397 (21%), Positives = 162/397 (40%), Gaps = 36/397 (9%)
Query: 21 RETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMK 80
+E K EL L T TN SK+ + ++ A +Q + E+D LR ++
Sbjct: 456 QELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLE 515
Query: 81 EQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRI---SEQINL---EIQRVKLKFQE 134
E+ L K Q Q + EE+ Q + ++N+ +I+ ++ + ++
Sbjct: 516 EKETMLNK---KTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRD 572
Query: 135 KLQELAPIPDLLKA-------TQMRLKDAQQAQAIAEHNAEQLARELN-CAREKVVHIFR 186
K ++++ + + +K+ T L ++A A E E+L + + REK I
Sbjct: 573 KEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDN 632
Query: 187 YLYSLY-LVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQM 245
Y L L ++L Q DL S+ E + + L + LK + ++
Sbjct: 633 YKKDLKDLKEKVSLLQGDL---SEKEASLLDLKEHASSLASSGLK----------KDSRL 679
Query: 246 ALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTR 305
L + Q E + ++S++++ + + S ++ R+Q E + E + +
Sbjct: 680 KTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSD-RIQHLEREITRYKDESSKAQ 738
Query: 306 DEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRL 365
E R L+ E E + +AELE + + QV K+ LK++ + K+
Sbjct: 739 AEVDRLLEILKE-VENEKNDKDKKIAELE---SLTSRQVKDQNKKVANLKHKEQVEKKKS 794
Query: 366 TENFEQAQLRILGLQTQVQSLRRTASSTGDGDGENQE 402
+ E+A+ R L Q L+ + D E +E
Sbjct: 795 AQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEE 831
Score = 34.7 bits (76), Expect = 0.60
Identities = 64/345 (18%), Positives = 137/345 (39%), Gaps = 27/345 (7%)
Query: 24 QNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQN 83
Q L E E L H + L S +++ ++ L+ + +EE ++ + +K+ +
Sbjct: 648 QGDLSEKEASLLDLKEHASSLASS---GLKKDSRLKTLEIALEQKKEECLKMESQLKKAH 704
Query: 84 DQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIP 143
+ + R + + ++ R+ +++ +++ ++ +K EK + I
Sbjct: 705 EAALEARASPEMSDR-IQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIA 763
Query: 144 DLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQED 203
+L T ++KD + A +H + ++ E+ L +L ++D
Sbjct: 764 ELESLTSRQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKD 823
Query: 204 LFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLK 263
+ E R ++V + + ++ R EKQ+ L + ++ K
Sbjct: 824 DRIEELEEALR----ESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKV-------K 872
Query: 264 SEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVR 323
E+E +KA + T++S E L A+ L+ + AL A + +
Sbjct: 873 QELESMKAKLSSTQQSLAEKETHLTNLR---AERRKHLEEVLEMKQEALLAAISEKD--- 926
Query: 324 KCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTEN 368
+A LE + + Q A +RE K+RL Q+K+ T+N
Sbjct: 927 ----ANIALLELSSSKKKTQEEVAALKRE--KDRLVQQLKQQTQN 965
Score = 31.1 bits (67), Expect = 7.4
Identities = 30/155 (19%), Positives = 68/155 (43%), Gaps = 9/155 (5%)
Query: 21 RETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMK 80
++ Q+ LR+ + + E L L S + E+E+ + + A ++++EL M+
Sbjct: 813 QQLQDSLRKKDDRIEELE---EALRESVQITAEREMVLAQEESARTNAEKQVEELLMAME 869
Query: 81 EQNDQLQDYRVKYLQAQQ-LVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQEL 139
+ +L+ + K QQ L E++ + E + ++ + + EK +
Sbjct: 870 KVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANI 929
Query: 140 APIPDLLKATQMRLKDAQQAQAIAEHNAEQLAREL 174
A LL+ + + K Q+ A + ++L ++L
Sbjct: 930 A----LLELSSSK-KKTQEEVAALKREKDRLVQQL 959
>X82834-1|CAA58041.1| 2185|Homo sapiens 256 kD golgin protein.
Length = 2185
Score = 48.4 bits (110), Expect = 5e-05
Identities = 75/374 (20%), Positives = 156/374 (41%), Gaps = 21/374 (5%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLM---GSKEQAFEQEVNVRALKQCYREAREEIDEL 75
Q E +N+++ ++ E L T L G+++QA ++ + + Q +E E I+ +
Sbjct: 1298 QLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKES--CITQLKKELSENINAV 1355
Query: 76 RTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEK 135
TLMKE+ + + + L Q + Q + + K + ++
Sbjct: 1356 -TLMKEELKE-KKVEISSLSKQLTDLNVQLQNSISLSEKEAAISSLRKQYDEEKCELLDQ 1413
Query: 136 LQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVT 195
+Q+L+ D L ++ ++ +Q + +E + + + + L L +
Sbjct: 1414 VQDLSFKVDTL--SKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLELKS 1471
Query: 196 TMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQ--RIS 253
+++ + E+ + NK L ++ + E+ + L +Q RI
Sbjct: 1472 KEAYEKDEQINLLKEELDQQNKRFDC---LKGEMEDDKSKMEKKESNLETELKSQTARIM 1528
Query: 254 QLAENNISLKS-EIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRAL 312
+L E++I+ K+ EIE L + + K L +K+ +LG E D EA +
Sbjct: 1529 EL-EDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKI 1587
Query: 313 QRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQ-MKRLTENFEQ 371
Q +++ L+T ELE V + E+E + L++RL + +L E +
Sbjct: 1588 LTLENQVYSMKAELETKKKELEH----VNLSVKSKEEELKALEDRLESESAAKLAELKRK 1643
Query: 372 AQLRILGLQTQVQS 385
A+ +I ++ Q+ S
Sbjct: 1644 AEQKIAAIKKQLLS 1657
Score = 42.7 bits (96), Expect = 0.002
Identities = 70/353 (19%), Positives = 143/353 (40%), Gaps = 26/353 (7%)
Query: 50 QAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXX 109
+ F +E N + + E + L TL +Q + Q+ +K + ++ ++ + Q
Sbjct: 256 EVFTKEENPESDGEPVVEDGTSVKTLETL--QQRVKRQENLLK--RCKETIQSHKEQCTL 311
Query: 110 XXXXNTRISEQINLEIQRV-KLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAE 168
+ EQ++ +Q + K+K ++ I L A + + Q +
Sbjct: 312 LTSEKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKR 371
Query: 169 QLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNS 228
Q+ L E++ + + MT E+L + Q E + + L +
Sbjct: 372 QMHETLEMKEEEIAQLRSR------IKQMTTQGEEL--REQKEKSERAAFEELEKALSTA 423
Query: 229 LKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQ 288
K E + + + ++ S+ E ISL+ E+ R+K V+ + + +
Sbjct: 424 QKTEEARRKLKAEMDEQIKTIEKTSE--EERISLQQELSRVKQEVVDVMKKSSEEQIAKL 481
Query: 289 EKMHECAQLGGELDRTRDEASRALQ-RAHEQTETVRKCLQTTVAELERQLAASRAQVSTA 347
+K+HE EL R E ++ LQ R E E ++ L+ + +E + Q S A
Sbjct: 482 QKLHE-----KELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQESLA 536
Query: 348 EKEREELKNRL----HWQMKRLTENFEQAQLRILGLQTQVQ-SLRRTASSTGD 395
+E E K + +++ L + E + RIL L++ ++ SL+ + + D
Sbjct: 537 LEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKD 589
Score = 37.1 bits (82), Expect = 0.11
Identities = 80/374 (21%), Positives = 150/374 (40%), Gaps = 38/374 (10%)
Query: 19 QHRETQNKLRELEMK--FEGLATHTNMLMGSKEQAFE-QEVNVRALKQCYREARE----E 71
QH E + ++ K E + + KE + E ++ L C +E E
Sbjct: 1814 QHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKIKELDSCLVRQKEVHRVE 1873
Query: 72 IDELRTLMKE-QNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKL 130
++EL + ++ Q Q D R K +L+EE + ++ N+E Q L
Sbjct: 1874 MEELTSKYEKLQALQQMDGRNK---PTELLEENTEEKSKSHLVQPKLLS--NMEAQHNDL 1928
Query: 131 KFQEKLQELAPIPDLLKATQMRL-KDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLY 189
+F KL L +RL KD + + + E L +E + RE+ + +
Sbjct: 1929 EF--KLAGAEREKQKLGKEIVRLQKDLRMLRKEHQQELEILKKEYDQEREEKIK--QEQE 1984
Query: 190 SLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLN 249
L L TL Q L + +++ + K+Q + + + ++ ++ E E N
Sbjct: 1985 DLELKHNSTLKQ--LMREFNTQLAQ--KEQELEMTIKETINKAQEV-EAELLESHQEETN 2039
Query: 250 QRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEAS 309
Q + ++AE + LK +R + + EE A + LQ ++ +E
Sbjct: 2040 QLLKKIAEKDDDLKRTAKRYEEILDAREEEMTAKVRDLQTQL--------------EELQ 2085
Query: 310 RALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENF 369
+ Q+ EQ E T+ EL+ QLA +S ++ + +E + ++H RL +
Sbjct: 2086 KKYQQKLEQEENPGND-NVTIMELQTQLAQKTTLISDSKLKEQEFREQIHNLEDRLKKYE 2144
Query: 370 EQAQLRILGLQTQV 383
+ +G T+V
Sbjct: 2145 KNVYATTVGHLTKV 2158
Score = 36.3 bits (80), Expect = 0.20
Identities = 72/353 (20%), Positives = 149/353 (42%), Gaps = 26/353 (7%)
Query: 49 EQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXX 108
+Q +++ N+ LK+C +E + E TL+ + + LQ+ + LQ + +++
Sbjct: 285 QQRVKRQENL--LKRC-KETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHMAEK 341
Query: 109 XXXXXNTR----ISEQINLE----IQRVKLKFQEKLQ----ELAPIPDLLKATQMRLKDA 156
R + EQ+ + I K + E L+ E+A + +K + ++
Sbjct: 342 TKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEEL 401
Query: 157 QQAQAIAEHNA-EQLARELNCAREKVVHIFRYLYSLY--LVTTMTLTQEDLFGQSQSEIG 213
++ + +E A E+L + L+ A +K R L + + T+ T E+ Q E+
Sbjct: 402 REQKEKSERAAFEELEKALSTA-QKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELS 460
Query: 214 RGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASV 273
R K + V V+ +S + K + EK++A Q +++ + E ++
Sbjct: 461 RV-KQEVVDVMKKSSEEQIAKLQKL--HEKELARKEQELTKKLQTREREFQEQMKVALEK 517
Query: 274 IRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAEL 333
++E ++ EK QE + +L + E+ L+ ++ ET R + + L
Sbjct: 518 SQSEYLKISQEKEQQESL-ALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSL 576
Query: 334 ERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSL 386
E+ L ++ Q E KN+ K +T E+ + + L+ Q +L
Sbjct: 577 EKSLQENKNQSKDLAVHLEAEKNK---HNKEITVMVEKHKTELESLKHQQDAL 626
>U41740-1|AAC50434.1| 2230|Homo sapiens trans-Golgi p230 protein.
Length = 2230
Score = 48.4 bits (110), Expect = 5e-05
Identities = 75/374 (20%), Positives = 156/374 (41%), Gaps = 21/374 (5%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLM---GSKEQAFEQEVNVRALKQCYREAREEIDEL 75
Q E +N+++ ++ E L T L G+++QA ++ + + Q +E E I+ +
Sbjct: 1298 QLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKES--CITQLKKELSENINAV 1355
Query: 76 RTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEK 135
TLMKE+ + + + L Q + Q + + K + ++
Sbjct: 1356 -TLMKEELKE-KKVEISSLSKQLTDLNVQLQNSISLSEKEAAISSLRKQYDEEKCELLDQ 1413
Query: 136 LQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVT 195
+Q+L+ D L ++ ++ +Q + +E + + + + L L +
Sbjct: 1414 VQDLSFKVDTL--SKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLELKS 1471
Query: 196 TMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQ--RIS 253
+++ + E+ + NK L ++ + E+ + L +Q RI
Sbjct: 1472 KEAYEKDEQINLLKEELDQQNKRFDC---LKGEMEDDKSKMEKKESNLETELKSQTARIM 1528
Query: 254 QLAENNISLKS-EIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRAL 312
+L E++I+ K+ EIE L + + K L +K+ +LG E D EA +
Sbjct: 1529 EL-EDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKI 1587
Query: 313 QRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQ-MKRLTENFEQ 371
Q +++ L+T ELE V + E+E + L++RL + +L E +
Sbjct: 1588 LTLENQVYSMKAELETKKKELEH----VNLSVKSKEEELKALEDRLESESAAKLAELKRK 1643
Query: 372 AQLRILGLQTQVQS 385
A+ +I ++ Q+ S
Sbjct: 1644 AEQKIAAIKKQLLS 1657
Score = 42.7 bits (96), Expect = 0.002
Identities = 70/353 (19%), Positives = 143/353 (40%), Gaps = 26/353 (7%)
Query: 50 QAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXX 109
+ F +E N + + E + L TL +Q + Q+ +K + ++ ++ + Q
Sbjct: 256 EVFTKEENPESDGEPVVEDGTSVKTLETL--QQRVKRQENLLK--RCKETIQSHKEQCTL 311
Query: 110 XXXXNTRISEQINLEIQRV-KLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAE 168
+ EQ++ +Q + K+K ++ I L A + + Q +
Sbjct: 312 LTSEKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKR 371
Query: 169 QLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNS 228
Q+ L E++ + + MT E+L + Q E + + L +
Sbjct: 372 QMHETLEMKEEEIAQLRSR------IKQMTTQGEEL--REQKEKSERAAFEELEKALSTA 423
Query: 229 LKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQ 288
K E + + + ++ S+ E ISL+ E+ R+K V+ + + +
Sbjct: 424 QKTEEARRKLKAEMDEQIKTIEKTSE--EERISLQQELSRVKQEVVDVMKKSSEEQIAKL 481
Query: 289 EKMHECAQLGGELDRTRDEASRALQ-RAHEQTETVRKCLQTTVAELERQLAASRAQVSTA 347
+K+HE EL R E ++ LQ R E E ++ L+ + +E + Q S A
Sbjct: 482 QKLHE-----KELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQESLA 536
Query: 348 EKEREELKNRL----HWQMKRLTENFEQAQLRILGLQTQVQ-SLRRTASSTGD 395
+E E K + +++ L + E + RIL L++ ++ SL+ + + D
Sbjct: 537 LEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKD 589
Score = 36.3 bits (80), Expect = 0.20
Identities = 72/353 (20%), Positives = 149/353 (42%), Gaps = 26/353 (7%)
Query: 49 EQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXX 108
+Q +++ N+ LK+C +E + E TL+ + + LQ+ + LQ + +++
Sbjct: 285 QQRVKRQENL--LKRC-KETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHMAEK 341
Query: 109 XXXXXNTR----ISEQINLE----IQRVKLKFQEKLQ----ELAPIPDLLKATQMRLKDA 156
R + EQ+ + I K + E L+ E+A + +K + ++
Sbjct: 342 TKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEEL 401
Query: 157 QQAQAIAEHNA-EQLARELNCAREKVVHIFRYLYSLY--LVTTMTLTQEDLFGQSQSEIG 213
++ + +E A E+L + L+ A +K R L + + T+ T E+ Q E+
Sbjct: 402 REQKEKSERAAFEELEKALSTA-QKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELS 460
Query: 214 RGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASV 273
R K + V V+ +S + K + EK++A Q +++ + E ++
Sbjct: 461 RV-KQEVVDVMKKSSEEQIAKLQKL--HEKELARKEQELTKKLQTREREFQEQMKVALEK 517
Query: 274 IRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAEL 333
++E ++ EK QE + +L + E+ L+ ++ ET R + + L
Sbjct: 518 SQSEYLKISQEKEQQESL-ALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSL 576
Query: 334 ERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSL 386
E+ L ++ Q E KN+ K +T E+ + + L+ Q +L
Sbjct: 577 EKSLQENKNQSKDLAVHLEAEKNK---HNKEITVMVEKHKTELESLKHQQDAL 626
Score = 35.5 bits (78), Expect = 0.35
Identities = 75/350 (21%), Positives = 141/350 (40%), Gaps = 38/350 (10%)
Query: 19 QHRETQNKLRELEMK--FEGLATHTNMLMGSKEQAFE-QEVNVRALKQCYREARE----E 71
QH E + ++ K E + + KE + E ++ L C +E E
Sbjct: 1814 QHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKIKELDSCLVRQKEVHRVE 1873
Query: 72 IDELRTLMKE-QNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKL 130
++EL + ++ Q Q D R K +L+EE + ++ N+E Q L
Sbjct: 1874 MEELTSKYEKLQALQQMDGRNK---PTELLEENTEEKSKSHLVQPKLLS--NMEAQHNDL 1928
Query: 131 KFQEKLQELAPIPDLLKATQMRL-KDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLY 189
+F KL L +RL KD + + + E L +E + RE+ + +
Sbjct: 1929 EF--KLAGAEREKQKLGKEIVRLQKDLRMLRKEHQQELEILKKEYDQEREEKIK--QEQE 1984
Query: 190 SLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLN 249
L L TL Q L + +++ + K+Q + + + ++ ++ E E N
Sbjct: 1985 DLELKHNSTLKQ--LMREFNTQLAQ--KEQELEMTIKETINKAQEV-EAELLESHQEETN 2039
Query: 250 QRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEAS 309
Q + ++AE + LK +R + + EE A + LQ ++ +E
Sbjct: 2040 QLLKKIAEKDDDLKRTAKRYEEILDAREEEMTAKVRDLQTQL--------------EELQ 2085
Query: 310 RALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLH 359
+ Q+ EQ E T+ EL+ QLA +S ++ + +E + ++H
Sbjct: 2086 KKYQQKLEQEENPGND-NVTIMELQTQLAQKTTLISDSKLKEQEFREQIH 2134
>U31906-1|AAC51791.1| 2083|Homo sapiens golgin-245 protein.
Length = 2083
Score = 48.4 bits (110), Expect = 5e-05
Identities = 75/374 (20%), Positives = 156/374 (41%), Gaps = 21/374 (5%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLM---GSKEQAFEQEVNVRALKQCYREAREEIDEL 75
Q E +N+++ ++ E L T L G+++QA ++ + + Q +E E I+ +
Sbjct: 1153 QLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKES--CITQLKKELSENINAV 1210
Query: 76 RTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEK 135
TLMKE+ + + + L Q + Q + + K + ++
Sbjct: 1211 -TLMKEELKE-KKVEISSLSKQLTDLNVQLQNSISLSEKEAAISSLRKQYDEEKCELLDQ 1268
Query: 136 LQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVT 195
+Q+L+ D L ++ ++ +Q + +E + + + + L L +
Sbjct: 1269 VQDLSFKVDTL--SKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLELKS 1326
Query: 196 TMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQ--RIS 253
+++ + E+ + NK L ++ + E+ + L +Q RI
Sbjct: 1327 KEAYEKDEQINLLKEELDQQNKRFDC---LKGEMEDDKSKMEKKESNLETELKSQTARIM 1383
Query: 254 QLAENNISLKS-EIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRAL 312
+L E++I+ K+ EIE L + + K L +K+ +LG E D EA +
Sbjct: 1384 EL-EDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKI 1442
Query: 313 QRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQ-MKRLTENFEQ 371
Q +++ L+T ELE V + E+E + L++RL + +L E +
Sbjct: 1443 LTLENQVYSMKAELETKKKELEH----VNLSVKSKEEELKALEDRLESESAAKLAELKRK 1498
Query: 372 AQLRILGLQTQVQS 385
A+ +I ++ Q+ S
Sbjct: 1499 AEQKIAAIKKQLLS 1512
Score = 42.7 bits (96), Expect = 0.002
Identities = 70/353 (19%), Positives = 143/353 (40%), Gaps = 26/353 (7%)
Query: 50 QAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXX 109
+ F +E N + + E + L TL +Q + Q+ +K + ++ ++ + Q
Sbjct: 111 EVFTKEENPESDGEPVVEDGASVKTLETL--QQRVKRQENLLK--RCKETIQSHKEQCTL 166
Query: 110 XXXXNTRISEQINLEIQRV-KLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAE 168
+ EQ++ +Q + K+K ++ I L A + + Q +
Sbjct: 167 LTSEKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKR 226
Query: 169 QLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNS 228
Q+ L E++ + + MT E+L + Q E + + L +
Sbjct: 227 QMHETLEMKEEEIAQLRSR------IKQMTTQGEEL--REQKEKSERAAFEELEKALSTA 278
Query: 229 LKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQ 288
K E + + + ++ S+ E ISL+ E+ R+K V+ + + +
Sbjct: 279 QKTEEARRKLKAEMDEQIKTIEKTSE--EERISLQQELSRVKQEVVDVMKKSSEEQIAKL 336
Query: 289 EKMHECAQLGGELDRTRDEASRALQ-RAHEQTETVRKCLQTTVAELERQLAASRAQVSTA 347
+K+HE EL R E ++ LQ R E E ++ L+ + +E + Q S A
Sbjct: 337 QKLHE-----KELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQESLA 391
Query: 348 EKEREELKNRL----HWQMKRLTENFEQAQLRILGLQTQVQ-SLRRTASSTGD 395
+E E K + +++ L + E + RIL L++ ++ SL+ + + D
Sbjct: 392 LEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENENQSKD 444
Score = 35.5 bits (78), Expect = 0.35
Identities = 72/353 (20%), Positives = 148/353 (41%), Gaps = 26/353 (7%)
Query: 49 EQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXX 108
+Q +++ N+ LK+C +E + E TL+ + + LQ+ + LQ + +++
Sbjct: 140 QQRVKRQENL--LKRC-KETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHMAEK 196
Query: 109 XXXXXNTR----ISEQINLE----IQRVKLKFQEKLQ----ELAPIPDLLKATQMRLKDA 156
R + EQ+ + I K + E L+ E+A + +K + ++
Sbjct: 197 TKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEEL 256
Query: 157 QQAQAIAEHNA-EQLARELNCAREKVVHIFRYLYSLY--LVTTMTLTQEDLFGQSQSEIG 213
++ + +E A E+L + L+ A +K R L + + T+ T E+ Q E+
Sbjct: 257 REQKEKSERAAFEELEKALSTA-QKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELS 315
Query: 214 RGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASV 273
R K + V V+ +S + K + EK++A Q +++ + E ++
Sbjct: 316 RV-KQEVVDVMKKSSEEQIAKLQKL--HEKELARKEQELTKKLQTREREFQEQMKVALEK 372
Query: 274 IRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAEL 333
++E ++ EK QE + +L + E+ L+ ++ ET R + + L
Sbjct: 373 SQSEYLKISQEKEQQESL-ALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSL 431
Query: 334 ERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSL 386
E+ L + Q E KN+ K +T E+ + + L+ Q +L
Sbjct: 432 EKSLQENENQSKDLAVHLEAEKNK---HNKEITVMVEKHKTELESLKHQQDAL 481
Score = 35.5 bits (78), Expect = 0.35
Identities = 75/350 (21%), Positives = 141/350 (40%), Gaps = 38/350 (10%)
Query: 19 QHRETQNKLRELEMK--FEGLATHTNMLMGSKEQAFE-QEVNVRALKQCYREARE----E 71
QH E + ++ K E + + KE + E ++ L C +E E
Sbjct: 1669 QHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKIKELDSCLVRQKEVHRVE 1728
Query: 72 IDELRTLMKE-QNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKL 130
++EL + ++ Q Q D R K +L+EE + ++ N+E Q L
Sbjct: 1729 MEELTSKYEKLQALQQMDGRNK---PTELLEENTEEKSKSHLVQPKLLS--NMEAQHNDL 1783
Query: 131 KFQEKLQELAPIPDLLKATQMRL-KDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLY 189
+F KL L +RL KD + + + E L +E + RE+ + +
Sbjct: 1784 EF--KLAGAEREKQKLGKEIVRLQKDLRMLRKEHQQELEILKKEYDQEREEKIK--QEQE 1839
Query: 190 SLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLN 249
L L TL Q L + +++ + K+Q + + + ++ ++ E E N
Sbjct: 1840 DLELKHNSTLKQ--LMREFNTQLAQ--KEQELEMTIKETINKAQEV-EAELLESHQEETN 1894
Query: 250 QRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEAS 309
Q + ++AE + LK +R + + EE A + LQ ++ +E
Sbjct: 1895 QLLKKIAEKDDDLKRTAKRYEEILDAREEEMTAKVRDLQTQL--------------EELQ 1940
Query: 310 RALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLH 359
+ Q+ EQ E T+ EL+ QLA +S ++ + +E + ++H
Sbjct: 1941 KKYQQKLEQEENPGND-NVTIMELQTQLAQKTTLISDSKLKEQEFREQIH 1989
>BC132736-1|AAI32737.1| 1843|Homo sapiens KIAA1212 protein.
Length = 1843
Score = 48.4 bits (110), Expect = 5e-05
Identities = 61/350 (17%), Positives = 151/350 (43%), Gaps = 23/350 (6%)
Query: 42 NMLMGSKEQAFEQEV--NVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQL 99
N + K + E E+ ++L+ C +++ + E + +++ + L++ + ++ +
Sbjct: 500 NQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKE-KAQLEKTIETLRENSERQIKILEQ 558
Query: 100 VEEQRRQXXXXXXXNTRISEQINL-EIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQ 158
E Q ++IS + + +I++ E ++E + ++ + ++K +
Sbjct: 559 ENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELE 618
Query: 159 AQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKD 218
AE+L EL+ ++ + + + +L + T + + Q SE+ R N+
Sbjct: 619 HYKEKGERAEELENELHHLEKENELLQKKITNLKI----TCEKIEALEQENSELERENRK 674
Query: 219 QTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEE 278
+ +L Q+ L + SQL E N+ L+ +E LK + ++ +
Sbjct: 675 LKKTLDSFKNLT------------FQLESLEKENSQLDEENLELRRNVESLKCASMKMAQ 722
Query: 279 SALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLA 338
L N++ EK E + G EL + + + L+ +++ + + LQ T+ +++
Sbjct: 723 LQLENKELESEK--EQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQ 780
Query: 339 ASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRR 388
+++ E E + L+ L ++K ++ EQ + L+ + L +
Sbjct: 781 QLESELQDLEMENQTLQKNLE-ELKISSKRLEQLEKENKSLEQETSQLEK 829
Score = 46.0 bits (104), Expect = 2e-04
Identities = 76/384 (19%), Positives = 165/384 (42%), Gaps = 29/384 (7%)
Query: 22 ETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKE 81
+ Q + +ELE + E L +L S ++ EV+ + L + ++ ++ +++
Sbjct: 722 QLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQ 781
Query: 82 QNDQLQDYRVKYLQAQQLVEEQR--RQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQEL 139
+LQD ++ Q+ +EE + + + EQ ++++ K + +++ + L
Sbjct: 782 LESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRL 841
Query: 140 APIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHI------FRYLYSLYL 193
++ T L++ E + L++E+ +E V + + L
Sbjct: 842 RQQAEIKDTT---LEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRAT 898
Query: 194 VTTMTLT--QEDLFGQS-QSEIGRGNKDQTVHVLLHNSL-KPPEKPPERGGDEKQMALLN 249
+ TL +EDL + +++ + ++ H L L K E+ D+ + LL
Sbjct: 899 IDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLE 958
Query: 250 QRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEAS 309
++ + ++ +K E++ A R EES N++ QE + + E + R +
Sbjct: 959 SKLESTLKKSLEIKE--EKIAALEARLEESTNYNQQLRQEL--KTVKKNYEALKQRQDEE 1014
Query: 310 RALQR----AHEQTETVRKCLQTT--VAELERQLAASRAQVSTAEKEREELKNRLHWQMK 363
R +Q + E + R+ +TT + +++ +L +T + E++ LK Q+K
Sbjct: 1015 RMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKT----QLK 1070
Query: 364 RLTENFEQAQLRILGLQTQVQSLR 387
+L Q +IL LQ Q SL+
Sbjct: 1071 QLETQNNNLQAQILALQRQTVSLQ 1094
Score = 32.7 bits (71), Expect = 2.4
Identities = 67/353 (18%), Positives = 151/353 (42%), Gaps = 27/353 (7%)
Query: 26 KLRELEMKFEGLATHTNMLMGSKEQAFEQ----EVNVRALKQCYREAREEIDELRTLMKE 81
K LE+ ++GL L + E + ++ E ++ L+ + ++ ++EL+ + +
Sbjct: 750 KTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELK-ISSK 808
Query: 82 QNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISE--QINLEIQRVKLKFQEKLQE- 138
+ +QL+ Q +E+ ++Q + +E LE VK+ EK +
Sbjct: 809 RLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKT 868
Query: 139 LAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMT 198
L+ + K + +RLK+ ++ A + L RE +V L + + +
Sbjct: 869 LSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVS--EKLKTQQMNNDLE 926
Query: 199 -LTQE-DLFGQSQSEI--GRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQ 254
LT E + G ++ + + D + + LL + L+ K +EK +A L R+ +
Sbjct: 927 KLTHELEKIGLNKERLLHDEQSTDDSRYKLLESKLESTLKKSLEIKEEK-IAALEARLEE 985
Query: 255 LAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRAL-- 312
N L+ E++ +K + ++ +E+R+ + + + +R E +R L
Sbjct: 986 STNYNQQLRQELKTVKKNYEALKQRQ--DEERMVQSSPPISGEDNKWERESQETTRELLK 1043
Query: 313 --------QRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNR 357
+R + + ++ L+T + +LE Q +AQ+ +++ L+ +
Sbjct: 1044 VKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQ 1096
>BC078168-1|AAH78168.1| 887|Homo sapiens KIAA1212 protein protein.
Length = 887
Score = 48.4 bits (110), Expect = 5e-05
Identities = 61/350 (17%), Positives = 151/350 (43%), Gaps = 23/350 (6%)
Query: 42 NMLMGSKEQAFEQEV--NVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQL 99
N + K + E E+ ++L+ C +++ + E + +++ + L++ + ++ +
Sbjct: 497 NQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKE-KAQLEKTIETLRENSERQIKILEQ 555
Query: 100 VEEQRRQXXXXXXXNTRISEQINL-EIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQ 158
E Q ++IS + + +I++ E ++E + ++ + ++K +
Sbjct: 556 ENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELE 615
Query: 159 AQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKD 218
AE+L EL+ ++ + + + +L + T + + Q SE+ R N+
Sbjct: 616 HYKEKGERAEELENELHHLEKENELLQKKITNLKI----TCEKIEALEQENSELERENRK 671
Query: 219 QTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEE 278
+ +L Q+ L + SQL E N+ L+ +E LK + ++ +
Sbjct: 672 LKKTLDSFKNLT------------FQLESLEKENSQLDEENLELRRNVESLKCASMKMAQ 719
Query: 279 SALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLA 338
L N++ EK E + G EL + + + L+ +++ + + LQ T+ +++
Sbjct: 720 LQLENKELESEK--EQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQ 777
Query: 339 ASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRR 388
+++ E E + L+ L ++K ++ EQ + L+ + L +
Sbjct: 778 QLESELQDLEMENQTLQKNLE-ELKISSKRLEQLEKENKSLEQETSQLEK 826
>BC052988-1|AAH52988.1| 980|Homo sapiens retinoic acid induced 14
protein.
Length = 980
Score = 48.4 bits (110), Expect = 5e-05
Identities = 42/178 (23%), Positives = 87/178 (48%), Gaps = 13/178 (7%)
Query: 21 RETQNKLRE-LEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLM 79
R + KL+ LE + LA+ + KE+ + V +R+ + + E + ++TL+
Sbjct: 786 RSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIRSEVS---QVKREKENIQTLL 842
Query: 80 KEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQEL 139
K + ++ + K+ QAQ+ + E +R ++IN E+ + K +E L L
Sbjct: 843 KSKEQEVNELLQKFQQAQEELAEMKRYSESSSKLEEDKDKKIN-EMSKEVTKLKEALNSL 901
Query: 140 APIPDLLKATQMRLKDAQQAQAIAEHNAEQLAREL-NCAR--EKVVHIFRYLYSLYLV 194
+ L +T + +QQ +A+ + +QL +L C + ++V+ ++R ++ LY V
Sbjct: 902 S---QLSYSTSSSKRQSQQLEAL-QQQVKQLQNQLAECKKQHQEVISVYR-MHLLYAV 954
Score = 44.0 bits (99), Expect = 0.001
Identities = 75/350 (21%), Positives = 152/350 (43%), Gaps = 45/350 (12%)
Query: 65 YREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLE 124
Y+EA+EEI +L+ +K Q Q +A E+ + R+ +++N +
Sbjct: 601 YQEAQEEIMKLKDTLKSQMTQ---------EASDEAEDMKE-------AMNRMIDELNKQ 644
Query: 125 IQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHI 184
+ + ++E EL D K + A+ AEH E+L + N +R K
Sbjct: 645 VSELSQLYKEAQAEL---EDYRKRKSLEDVTAEYIHK-AEH--EKLMQLTNVSRAKAEDA 698
Query: 185 FRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQ 244
+ S Y LTQ +Q E + T H+ + +L+ K E +
Sbjct: 699 LSEMKSQYSKVLNELTQLKQLVDAQKE---NSVSITEHLQVITTLRTAAKEMEEKISNLK 755
Query: 245 MALLNQRI------SQLAENNISL------KSEIERLKASVIRTEESALANEKRLQEKMH 292
L ++ + QL E ++ +S E+L++S + +E S LA+ +L+E +
Sbjct: 756 EHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSS-LESEVSVLAS--KLKESVK 812
Query: 293 ECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKERE 352
E ++ E+ + R E S+ ++R E +T+ K + V EL ++ ++ +++ ++ E
Sbjct: 813 EKEKVHSEVVQIRSEVSQ-VKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYSE 871
Query: 353 ELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRRTASSTGDGDGENQE 402
+ K++ E ++ + L+ + SL + + ST ++Q+
Sbjct: 872 SSSKLEEDKDKKINEMSKE----VTKLKEALNSLSQLSYSTSSSKRQSQQ 917
Score = 32.7 bits (71), Expect = 2.4
Identities = 54/306 (17%), Positives = 122/306 (39%), Gaps = 22/306 (7%)
Query: 53 EQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDY--RVKYLQAQQLVEEQR-RQXXX 109
E V L Q Y+EA+ E+++ R K D +Y + ++ + QL R +
Sbjct: 640 ELNKQVSELSQLYKEAQAELEDYRK-RKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDA 698
Query: 110 XXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQ 169
++ S+ +N Q +L +K ++ L T +R + + I+
Sbjct: 699 LSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHL 758
Query: 170 LARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSL 229
++E+ A+ + + L T + + + QS + + V VL + L
Sbjct: 759 ASKEVEVAK-----LEKQLLEEKAAMTDAMVPRSSYEKLQSSL-----ESEVSVLA-SKL 807
Query: 230 KPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQE 289
K K E+ E + + +SQ+ K I+ L S + L ++ QE
Sbjct: 808 KESVKEKEKVHSE--VVQIRSEVSQVKRE----KENIQTLLKSKEQEVNELLQKFQQAQE 861
Query: 290 KMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEK 349
++ E + + ++ + + ++ +++ L ++++L ++S+ Q E
Sbjct: 862 ELAEMKRYSESSSKLEEDKDKKINEMSKEVTKLKEAL-NSLSQLSYSTSSSKRQSQQLEA 920
Query: 350 EREELK 355
++++K
Sbjct: 921 LQQQVK 926
>AY354204-1|AAQ63889.2| 972|Homo sapiens retinoic acid induced 14
isoform protein.
Length = 972
Score = 48.4 bits (110), Expect = 5e-05
Identities = 42/178 (23%), Positives = 87/178 (48%), Gaps = 13/178 (7%)
Query: 21 RETQNKLRE-LEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLM 79
R + KL+ LE + LA+ + KE+ + V +R+ + + E + ++TL+
Sbjct: 778 RSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIRSEVS---QVKREKENIQTLL 834
Query: 80 KEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQEL 139
K + ++ + K+ QAQ+ + E +R ++IN E+ + K +E L L
Sbjct: 835 KSKEQEVNELLQKFQQAQEELAEMKRYAESSSKLEEDKDKKIN-EMSKEVTKLKEALNSL 893
Query: 140 APIPDLLKATQMRLKDAQQAQAIAEHNAEQLAREL-NCAR--EKVVHIFRYLYSLYLV 194
+ L +T + +QQ +A+ + +QL +L C + ++V+ ++R ++ LY V
Sbjct: 894 S---QLSYSTSSSKRQSQQLEAL-QQQVKQLQNQLAECKKQHQEVISVYR-MHLLYAV 946
Score = 33.1 bits (72), Expect = 1.8
Identities = 55/307 (17%), Positives = 125/307 (40%), Gaps = 24/307 (7%)
Query: 53 EQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXX 112
E V L Q Y+EA+ E+++ R + L+D +Y+ + E+ Q
Sbjct: 632 ELNKQVSELSQLYKEAQAELEDYR-----KRKSLEDVTAEYIHKAE--HEKLMQLTNVSR 684
Query: 113 XNTRISEQINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLAR 172
+E E++ K +L +L + D K + + + Q A+++
Sbjct: 685 AK---AEDALSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEE 741
Query: 173 ELNCARE----KVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNS 228
+++ +E K V + + L L +T + + +S E + + + V VL +
Sbjct: 742 KISNLKEHLASKEVEVLK-LEKQLLEEKAAMT-DAMVPRSSYEKLQSSLESEVSVLA-SK 798
Query: 229 LKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQ 288
LK K E+ E + + +SQ+ K I+ L S + L ++ Q
Sbjct: 799 LKESVKEKEKVHSE--VVQIRSEVSQVKRE----KENIQTLLKSKEQEVNELLQKFQQAQ 852
Query: 289 EKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAE 348
E++ E + + ++ + + ++ +++ L ++++L ++S+ Q E
Sbjct: 853 EELAEMKRYAESSSKLEEDKDKKINEMSKEVTKLKEAL-NSLSQLSYSTSSSKRQSQQLE 911
Query: 349 KEREELK 355
++++K
Sbjct: 912 ALQQQVK 918
>AY317139-1|AAP84319.1| 983|Homo sapiens RAI14 isoform protein.
Length = 983
Score = 48.4 bits (110), Expect = 5e-05
Identities = 42/178 (23%), Positives = 87/178 (48%), Gaps = 13/178 (7%)
Query: 21 RETQNKLRE-LEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLM 79
R + KL+ LE + LA+ + KE+ + V +R+ + + E + ++TL+
Sbjct: 789 RSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIRSEVS---QVKREKENIQTLL 845
Query: 80 KEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQEL 139
K + ++ + K+ QAQ+ + E +R ++IN E+ + K +E L L
Sbjct: 846 KSKEQEVNELLQKFQQAQEELAEMKRYAESSSKLEEDKDKKIN-EMSKEVTKLKEALNSL 904
Query: 140 APIPDLLKATQMRLKDAQQAQAIAEHNAEQLAREL-NCAR--EKVVHIFRYLYSLYLV 194
+ L +T + +QQ +A+ + +QL +L C + ++V+ ++R ++ LY V
Sbjct: 905 S---QLSYSTSSSKRQSQQLEAL-QQQVKQLQNQLAECKKQHQEVISVYR-MHLLYAV 957
Score = 44.0 bits (99), Expect = 0.001
Identities = 75/350 (21%), Positives = 152/350 (43%), Gaps = 45/350 (12%)
Query: 65 YREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLE 124
Y+EA+EEI +L+ +K Q Q +A E+ + R+ +++N +
Sbjct: 604 YQEAQEEIMKLKDTLKSQMTQ---------EASDEAEDMKE-------AMNRMIDELNKQ 647
Query: 125 IQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHI 184
+ + ++E EL D K + A+ AEH E+L + N +R K
Sbjct: 648 VSELSQLYKEAQAEL---EDYRKRKSLEDVTAEYIHK-AEH--EKLMQLTNVSRAKAEDA 701
Query: 185 FRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQ 244
+ S Y LTQ +Q E + T H+ + +L+ K E +
Sbjct: 702 LSEMKSQYSKVLNELTQLKQLVDAQKE---NSVSITEHLQVITTLRTAAKEMEEKISNLK 758
Query: 245 MALLNQRI------SQLAENNISL------KSEIERLKASVIRTEESALANEKRLQEKMH 292
L ++ + QL E ++ +S E+L++S + +E S LA+ +L+E +
Sbjct: 759 EHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSS-LESEVSVLAS--KLKESVK 815
Query: 293 ECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKERE 352
E ++ E+ + R E S+ ++R E +T+ K + V EL ++ ++ +++ ++ E
Sbjct: 816 EKEKVHSEVVQIRSEVSQ-VKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYAE 874
Query: 353 ELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRRTASSTGDGDGENQE 402
+ K++ E ++ + L+ + SL + + ST ++Q+
Sbjct: 875 SSSKLEEDKDKKINEMSKE----VTKLKEALNSLSQLSYSTSSSKRQSQQ 920
Score = 32.7 bits (71), Expect = 2.4
Identities = 53/304 (17%), Positives = 124/304 (40%), Gaps = 18/304 (5%)
Query: 53 EQEVNVRALKQCYREAREEIDELRT-----------LMKEQNDQL-QDYRVKYLQAQQLV 100
E V L Q Y+EA+ E+++ R + K ++++L Q V +A+ +
Sbjct: 643 ELNKQVSELSQLYKEAQAELEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDAL 702
Query: 101 EEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQ 160
E + Q T++ + ++ + + + E LQ + + K + ++ + ++
Sbjct: 703 SEMKSQYSKVLNELTQLKQLVDAQKEN-SVSITEHLQVITTLRTAAKEMEEKISNLKEHL 761
Query: 161 AIAEHNAEQLARELNCAREKVVHIFRYL-YSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQ 219
A E +L ++L EK + S Y +L E S+ + K++
Sbjct: 762 ASKEVEVAKLEKQL--LEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEK 819
Query: 220 TVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEES 279
++ + + E+ + + Q +++L + + E+ +K + +
Sbjct: 820 VHSEVVQIRSEVSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYAESSSKL 879
Query: 280 ALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAA 339
+K++ E E +L L+ + + S + + Q++ + + LQ V +L+ QLA
Sbjct: 880 EEDKDKKINEMSKEVTKLKEALN-SLSQLSYSTSSSKRQSQQL-EALQQQVKQLQNQLAE 937
Query: 340 SRAQ 343
+ Q
Sbjct: 938 CKKQ 941
>AY165122-1|AAO39147.1| 1995|Homo sapiens myosin heavy chain protein.
Length = 1995
Score = 48.4 bits (110), Expect = 5e-05
Identities = 67/319 (21%), Positives = 139/319 (43%), Gaps = 27/319 (8%)
Query: 67 EAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQ 126
+ R+E+++L+ + ++ +LQ+ V + QQ EE R Q R E++ +
Sbjct: 1065 KGRQELEKLKRRLDGESSELQEQMV---EQQQRAEELRAQLG-------RKEEELQAALA 1114
Query: 127 RVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFR 186
R + + + Q L + + A +D + ++ +A AE+ R+L E +
Sbjct: 1115 RAEDEGGARAQLLKSLREAQAALAEAQEDLE-SERVARTKAEKQRRDLGEELEALRG--- 1170
Query: 187 YLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPP--EKPPERGGD-EK 243
L T Q++L + + E+ K +H + ++ + G+ +
Sbjct: 1171 ---ELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAE 1227
Query: 244 QMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANE---KRLQEKMHECAQLGGE 300
Q+ + + ++L++E+ L+A + + + E +RL+ ++ E G+
Sbjct: 1228 QLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGD 1287
Query: 301 LDRTRDEASRALQRAHEQTETVRKCL---QTTVAELERQLAASRAQVSTA-EKEREELKN 356
+R R EA+ LQRA + E V L ++ L ++L+++ AQ+ A E +EE +
Sbjct: 1288 GERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRA 1347
Query: 357 RLHWQMKRLTENFEQAQLR 375
+L + E A LR
Sbjct: 1348 KLALGSRVRAMEAEAAGLR 1366
Score = 42.3 bits (95), Expect = 0.003
Identities = 67/318 (21%), Positives = 128/318 (40%), Gaps = 22/318 (6%)
Query: 53 EQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXX 112
E+ V L++ R ++E+D+ +++Q + K + QL+ E++
Sbjct: 1427 EKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVE 1486
Query: 113 XNTRIS------EQINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHN 166
R E L + R + QE +EL L+A L ++ + H
Sbjct: 1487 ERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHE 1546
Query: 167 AEQLAR----ELNCAREKVVHIFRYLYSLY-LVTTMTLTQEDLFGQSQSEI-GRGNKDQT 220
E+ R N R +V + L + + +T + L Q + ++ GR +
Sbjct: 1547 LERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEE 1606
Query: 221 VHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESA 280
L L+ E ER + KQ L +A L+ E+E LKA + +
Sbjct: 1607 RRRQLAKQLRDAEV--ERDEERKQRTLA------VAARK-KLEGELEELKAQMASAGQGK 1657
Query: 281 LANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAAS 340
K+L++ + +L E++ TR + + ++E K L+ V L+ +LAAS
Sbjct: 1658 EEAVKQLRKMQAQMKELWREVEETRTSREEIFSQ-NRESEKRLKGLEAEVLRLQEELAAS 1716
Query: 341 RAQVSTAEKEREELKNRL 358
A+++R+E+ + +
Sbjct: 1717 DRARRQAQQDRDEMADEV 1734
Score = 40.3 bits (90), Expect = 0.012
Identities = 71/369 (19%), Positives = 152/369 (41%), Gaps = 32/369 (8%)
Query: 22 ETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKE 81
E Q ELE + L L+ SK+ + +V L++ R A + ++LR + E
Sbjct: 1511 EEQEAREELERQNRALRAELEALLSSKDDVGK---SVHELERACRVAEQAANDLRAQVTE 1567
Query: 82 QNDQL---QDYRVKY-LQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQ 137
D+L +D +++ + Q L + R Q+ +++ +++ E+ +
Sbjct: 1568 LEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERK 1627
Query: 138 ELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTM 197
+ K + L++ + A A E+ ++L + ++ ++R + T
Sbjct: 1628 QRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEE-----TR 1682
Query: 198 TLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGG-DEKQMA--LLNQRISQ 254
T ++E++F Q++ R + + L L ++ + D +MA + N +S+
Sbjct: 1683 T-SREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSK 1741
Query: 255 LA--ENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRA- 311
A E L+ + +L+ + + ++ R ++ + + L EL R +++A
Sbjct: 1742 AAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAE 1801
Query: 312 --LQRAHEQTETVRKCL-----------QTTVAELERQLAASRAQVSTAEKEREELKNRL 358
Q+ Q + +R L + T+A LE +LA + Q+ +ER +
Sbjct: 1802 SGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLV 1861
Query: 359 HWQMKRLTE 367
KRL E
Sbjct: 1862 RRAEKRLKE 1870
Score = 37.1 bits (82), Expect = 0.11
Identities = 78/353 (22%), Positives = 155/353 (43%), Gaps = 33/353 (9%)
Query: 39 THTNMLMGSKEQAFEQEV-NVRALKQCYREAREEID-ELRTLMKEQND--QLQDYRVKYL 94
T + +GS+ +A E E +R + ARE EL+T + ++ + Q+ L
Sbjct: 1345 TRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGAL 1404
Query: 95 QAQQLVEEQRRQXXXXXXXNTRISEQINL--EIQRVKLKFQEKLQELAPIPDLLKATQMR 152
+A + E +RR R++E+ ++R + + Q++L + + +
Sbjct: 1405 EAGE--EARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVST 1462
Query: 153 LKDAQQA--QAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQS 210
L+ Q+ Q +AE A L R + RE+ R + L T L +E +++
Sbjct: 1463 LEKKQRKFDQLLAEEKAAVL-RAVE-ERERAEAEGREREARALSLTRALEEEQ---EARE 1517
Query: 211 EIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLK 270
E+ R N+ + +L + + E + A R+++ A N+ L++++ L+
Sbjct: 1518 ELERQNRALRAEL---EALLSSKDDVGKSVHELERAC---RVAEQAAND--LRAQVTELE 1569
Query: 271 ASVIRTEESALANEKRLQ--EKMHECAQLGGEL--DRTRDEASRALQRAHEQTETVRKCL 326
+ E++ L E +Q + HE G + + R + ++ L+ A + + RK
Sbjct: 1570 DELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQR 1629
Query: 327 QTTVA---ELERQLAASRAQVSTAEKEREELKNRL---HWQMKRLTENFEQAQ 373
VA +LE +L +AQ+++A + +EE +L QMK L E+ +
Sbjct: 1630 TLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETR 1682
Score = 36.7 bits (81), Expect = 0.15
Identities = 63/346 (18%), Positives = 143/346 (41%), Gaps = 13/346 (3%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKE----QAFEQEVNVRALKQCYREAREEIDE 74
+ R+ +LR+ E++ + + + +++ + E + + + Q EA +++ +
Sbjct: 1607 RRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRK 1666
Query: 75 LRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQE 134
++ MKE ++++ R + E ++ R+ E++ R + + Q+
Sbjct: 1667 MQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAAS-DRARRQAQQ 1725
Query: 135 KLQELAP-IPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYL 193
E+A + + + L++ +Q + E+L E + + E + +R L
Sbjct: 1726 DRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNS-ELLNDRYRKLLLQVE 1784
Query: 194 VTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRIS 253
T L+ E F +++E GR ++ + L E R + +A L +++
Sbjct: 1785 SLTTELSAERSFS-AKAESGRQQLERQIQEL--RGRLGEEDAGARARHKMTIAALESKLA 1841
Query: 254 QLAENNISLKSEIERLKASVIRTEESALANEK-RLQEKMHECAQLGGELDRTRDEASRAL 312
Q AE + ++ L ++R E L +++E+ QL +L++ + L
Sbjct: 1842 Q-AEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQ-L 1899
Query: 313 QRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRL 358
+R E+ E Q L+R+L + +E L+NRL
Sbjct: 1900 KRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRL 1945
>AL137068-5|CAI12358.1| 1773|Homo sapiens centrosomal protein 110kDa
protein.
Length = 1773
Score = 48.4 bits (110), Expect = 5e-05
Identities = 79/391 (20%), Positives = 164/391 (41%), Gaps = 29/391 (7%)
Query: 19 QHRETQNKLRELEMKFEGLAT---HTNMLMGSKEQAFEQEV-----NVRALKQCYREARE 70
+H +N++ LE + L + + SK Q+ E+E+ N+ L Q +
Sbjct: 765 EHHNLENEVSRLEDIMQHLKSKKREERWMRASKRQS-EKEMEELHHNIDDLLQEKKSLEC 823
Query: 71 EIDEL-RTLMKEQNDQ-LQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQI---NLEI 125
E++EL RT+ K Q + D V+ L + +E+ + I + + E+
Sbjct: 824 EVEELHRTVQKRQQQKDFIDGNVESLMTELEIEKSLKHHEDIVDEIECIEKTLLKRRSEL 883
Query: 126 QRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIF 185
+ E EL+ + K + DA+++ E +AE+L R +V
Sbjct: 884 READRLLAEAESELSCTKEKTKNAVEKFTDAKRSLLQTESDAEELERRAQETAVNLVKAD 943
Query: 186 RYLYSLYL----VTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGD 241
+ L SL + + QE++ + + KD L K E+ + D
Sbjct: 944 QQLRSLQADAKDLEQHKIKQEEILKEINKIVAA--KDSDFQCLSKKKEKLTEELQKLQKD 1001
Query: 242 EKQMALLNQ--RISQLAENNISL---KSEIERLKASVIRTEESALANEKRLQEKMHECAQ 296
+MA N+ + L E+ + L ++E+E+LK+ V ++ +++L K E
Sbjct: 1002 I-EMAERNEDHHLQVLKESEVLLQAKRAELEKLKSQVTSQQQEMAVLDRQLGHKKEELHL 1060
Query: 297 LGGELDRTRDEASRALQRAHEQTETVRKCLQ-TTVAELERQLAASRAQVSTAEKEREELK 355
L G + + + + AL+ +TE KC V L +L+ + +++ ER+
Sbjct: 1061 LQGSMVQAKADLQEALRLG--ETEVTEKCNHIREVKSLLEELSFQKGELNVQISERKTQL 1118
Query: 356 NRLHWQMKRLTENFEQAQLRILGLQTQVQSL 386
+ ++++ EN + ++ +T+++++
Sbjct: 1119 TLIKQEIEKEEENLQVVLRQMSKHKTELKNI 1149
Score = 42.7 bits (96), Expect = 0.002
Identities = 83/386 (21%), Positives = 160/386 (41%), Gaps = 49/386 (12%)
Query: 18 CQHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRT 77
C +E ++ + ++ + LA +L ++E + ++ N+ L+ R+ ++E+D+L
Sbjct: 1232 CLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENSKMEQSNLEKLELNVRKLQQELDQLN- 1290
Query: 78 LMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRV--KLKFQEK 135
D+L + QQL +E+R + + +NL Q + K Q+
Sbjct: 1291 -----RDKLSLHNDISAMQQQL-QEKREAVNSLQEELANVQDHLNLAKQDLLHTTKHQDV 1344
Query: 136 L-QELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLV 194
L E + + R +D Q+ + + + L E+ + K+V
Sbjct: 1345 LLSEQTRLQKDISEWANRFEDCQKEEETKQQQLQVLQNEIEENKLKLVQ----------- 1393
Query: 195 TTMTLTQEDLFGQSQSEI-GRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRIS 253
QE +F + Q E +K +T V L EK D+K L+Q +S
Sbjct: 1394 ------QEMMFQRLQKERESEESKLETSKVTLKEQQHQLEKELT---DQKSK--LDQVLS 1442
Query: 254 QL--AENNISLKSEIER----LKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDE 307
++ AE + E ER L+ ++ +T+ E++L EK E L E D R +
Sbjct: 1443 KVLAAEERVRTLQEEERWCESLEKTLSQTKRQLSEREQQLVEKSGELLALQKEADSMRAD 1502
Query: 308 AS-------RALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKER---EELKNR 357
S ++A +Q ++++ L+ ++LE+ L + + S +KE E +
Sbjct: 1503 FSLLRNQFLTERKKAEKQVASLKEALKIQRSQLEKNLLEQKQENSCIQKEMATIELVAQD 1562
Query: 358 LHWQMKRLTENFEQAQLRILGLQTQV 383
H + +RL + Q Q L+ Q+
Sbjct: 1563 NHERARRLMKELNQMQYEYTELKKQM 1588
Score = 34.7 bits (76), Expect = 0.60
Identities = 31/127 (24%), Positives = 63/127 (49%), Gaps = 7/127 (5%)
Query: 242 EKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQE-KMHECAQLGGE 300
EK+ L + Q++++ LK+ ++ L+ + L +++R+ E + + A L +
Sbjct: 1126 EKEEENLQVVLRQMSKHKTELKNILDMLQLENHELQGLKLQHDQRVSELEKTQVAVLEEK 1185
Query: 301 LDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAE---KEREELKNR 357
L+ + + Q+ + E ++ L+ E+ER A SRA S E KE+E+L+ +
Sbjct: 1186 LEL--ENLQQISQQQKGEIEWQKQLLERDKREIERMTAESRALQSCVECLSKEKEDLQEK 1243
Query: 358 LH-WQMK 363
W+ K
Sbjct: 1244 CDIWEKK 1250
Score = 32.3 bits (70), Expect = 3.2
Identities = 37/142 (26%), Positives = 70/142 (49%), Gaps = 18/142 (12%)
Query: 241 DEKQMALLNQRISQLAENNISLKSEIERLKASVIRTE----ESALANEKR----LQEKMH 292
DEK+ L QR++++ + L EI + A +R E ESAL + LQ+
Sbjct: 92 DEKETLL--QRLTEVEQERDQL--EIVAMDAENMRKELAELESALQEQHEVNASLQQTQG 147
Query: 293 ECAQLGGELD---RTRDEASRALQRAHEQTETVRKCLQTTV-AELERQLAASRAQVSTAE 348
+ + EL+ RD + L+ E+ + + Q+ + AELE++ A + + A+
Sbjct: 148 DLSAYEAELEARLNLRDAEANQLKEELEKVTRLTQLEQSALQAELEKERQALKNALGKAQ 207
Query: 349 --KEREELKNRLHWQMKRLTEN 368
+E+E+ + LH ++K L ++
Sbjct: 208 FSEEKEQENSELHAKLKHLQDD 229
Score = 30.7 bits (66), Expect = 9.8
Identities = 68/392 (17%), Positives = 155/392 (39%), Gaps = 34/392 (8%)
Query: 17 RCQHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELR 76
+ Q Q ++ L+ + ++L GS QA L++ R E+ E
Sbjct: 1034 KSQVTSQQQEMAVLDRQLGHKKEELHLLQGSMVQAKAD------LQEALRLGETEVTEKC 1087
Query: 77 TLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKL 136
++E L++ + + + E++ Q T I ++I E + +++ ++
Sbjct: 1088 NHIREVKSLLEELSFQKGELNVQISERKTQL-------TLIKQEIEKEEENLQVVLRQMS 1140
Query: 137 QELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTT 196
+ + ++L Q+ + Q + + +L + E+ + +
Sbjct: 1141 KHKTELKNILDMLQLENHELQGLKLQHDQRVSELEKTQVAVLEEKLELENLQQISQQQKG 1200
Query: 197 MTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGD--EKQMALLNQRISQ 254
Q+ L + + EI R + L ++ + D EK++A + ++
Sbjct: 1201 EIEWQKQLLERDKREIERMTAESRALQSCVECLSKEKEDLQEKCDIWEKKLAQTKRVLAA 1260
Query: 255 LAENNISLKSEIERLKASV---------IRTEESALAN-----EKRLQEKMHECAQLGGE 300
EN+ +S +E+L+ +V + ++ +L N +++LQEK L E
Sbjct: 1261 AEENSKMEQSNLEKLELNVRKLQQELDQLNRDKLSLHNDISAMQQQLQEKREAVNSLQEE 1320
Query: 301 LDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHW 360
L +D + A Q T+ + L + L++ ++ + +KE EE K +
Sbjct: 1321 LANVQDHLNLAKQDLLHTTKH-QDVLLSEQTRLQKDISEWANRFEDCQKE-EETKQQ--- 1375
Query: 361 QMKRLTENFEQAQLRILGLQTQVQSLRRTASS 392
Q++ L E+ +L+++ + Q L++ S
Sbjct: 1376 QLQVLQNEIEENKLKLVQQEMMFQRLQKERES 1407
>AL137068-2|CAM13285.1| 2325|Homo sapiens centrosomal protein 110kDa
protein.
Length = 2325
Score = 48.4 bits (110), Expect = 5e-05
Identities = 79/391 (20%), Positives = 164/391 (41%), Gaps = 29/391 (7%)
Query: 19 QHRETQNKLRELEMKFEGLAT---HTNMLMGSKEQAFEQEV-----NVRALKQCYREARE 70
+H +N++ LE + L + + SK Q+ E+E+ N+ L Q +
Sbjct: 1317 EHHNLENEVSRLEDIMQHLKSKKREERWMRASKRQS-EKEMEELHHNIDDLLQEKKSLEC 1375
Query: 71 EIDEL-RTLMKEQNDQ-LQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQI---NLEI 125
E++EL RT+ K Q + D V+ L + +E+ + I + + E+
Sbjct: 1376 EVEELHRTVQKRQQQKDFIDGNVESLMTELEIEKSLKHHEDIVDEIECIEKTLLKRRSEL 1435
Query: 126 QRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIF 185
+ E EL+ + K + DA+++ E +AE+L R +V
Sbjct: 1436 READRLLAEAESELSCTKEKTKNAVEKFTDAKRSLLQTESDAEELERRAQETAVNLVKAD 1495
Query: 186 RYLYSLYL----VTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGD 241
+ L SL + + QE++ + + KD L K E+ + D
Sbjct: 1496 QQLRSLQADAKDLEQHKIKQEEILKEINKIVAA--KDSDFQCLSKKKEKLTEELQKLQKD 1553
Query: 242 EKQMALLNQ--RISQLAENNISL---KSEIERLKASVIRTEESALANEKRLQEKMHECAQ 296
+MA N+ + L E+ + L ++E+E+LK+ V ++ +++L K E
Sbjct: 1554 I-EMAERNEDHHLQVLKESEVLLQAKRAELEKLKSQVTSQQQEMAVLDRQLGHKKEELHL 1612
Query: 297 LGGELDRTRDEASRALQRAHEQTETVRKCLQ-TTVAELERQLAASRAQVSTAEKEREELK 355
L G + + + + AL+ +TE KC V L +L+ + +++ ER+
Sbjct: 1613 LQGSMVQAKADLQEALRLG--ETEVTEKCNHIREVKSLLEELSFQKGELNVQISERKTQL 1670
Query: 356 NRLHWQMKRLTENFEQAQLRILGLQTQVQSL 386
+ ++++ EN + ++ +T+++++
Sbjct: 1671 TLIKQEIEKEEENLQVVLRQMSKHKTELKNI 1701
Score = 42.7 bits (96), Expect = 0.002
Identities = 83/386 (21%), Positives = 160/386 (41%), Gaps = 49/386 (12%)
Query: 18 CQHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRT 77
C +E ++ + ++ + LA +L ++E + ++ N+ L+ R+ ++E+D+L
Sbjct: 1784 CLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENSKMEQSNLEKLELNVRKLQQELDQLN- 1842
Query: 78 LMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRV--KLKFQEK 135
D+L + QQL +E+R + + +NL Q + K Q+
Sbjct: 1843 -----RDKLSLHNDISAMQQQL-QEKREAVNSLQEELANVQDHLNLAKQDLLHTTKHQDV 1896
Query: 136 L-QELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLV 194
L E + + R +D Q+ + + + L E+ + K+V
Sbjct: 1897 LLSEQTRLQKDISEWANRFEDCQKEEETKQQQLQVLQNEIEENKLKLVQ----------- 1945
Query: 195 TTMTLTQEDLFGQSQSEI-GRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRIS 253
QE +F + Q E +K +T V L EK D+K L+Q +S
Sbjct: 1946 ------QEMMFQRLQKERESEESKLETSKVTLKEQQHQLEKELT---DQKSK--LDQVLS 1994
Query: 254 QL--AENNISLKSEIER----LKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDE 307
++ AE + E ER L+ ++ +T+ E++L EK E L E D R +
Sbjct: 1995 KVLAAEERVRTLQEEERWCESLEKTLSQTKRQLSEREQQLVEKSGELLALQKEADSMRAD 2054
Query: 308 AS-------RALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKER---EELKNR 357
S ++A +Q ++++ L+ ++LE+ L + + S +KE E +
Sbjct: 2055 FSLLRNQFLTERKKAEKQVASLKEALKIQRSQLEKNLLEQKQENSCIQKEMATIELVAQD 2114
Query: 358 LHWQMKRLTENFEQAQLRILGLQTQV 383
H + +RL + Q Q L+ Q+
Sbjct: 2115 NHERARRLMKELNQMQYEYTELKKQM 2140
Score = 34.7 bits (76), Expect = 0.60
Identities = 31/127 (24%), Positives = 63/127 (49%), Gaps = 7/127 (5%)
Query: 242 EKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQE-KMHECAQLGGE 300
EK+ L + Q++++ LK+ ++ L+ + L +++R+ E + + A L +
Sbjct: 1678 EKEEENLQVVLRQMSKHKTELKNILDMLQLENHELQGLKLQHDQRVSELEKTQVAVLEEK 1737
Query: 301 LDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAE---KEREELKNR 357
L+ + + Q+ + E ++ L+ E+ER A SRA S E KE+E+L+ +
Sbjct: 1738 LEL--ENLQQISQQQKGEIEWQKQLLERDKREIERMTAESRALQSCVECLSKEKEDLQEK 1795
Query: 358 LH-WQMK 363
W+ K
Sbjct: 1796 CDIWEKK 1802
Score = 32.3 bits (70), Expect = 3.2
Identities = 37/142 (26%), Positives = 70/142 (49%), Gaps = 18/142 (12%)
Query: 241 DEKQMALLNQRISQLAENNISLKSEIERLKASVIRTE----ESALANEKR----LQEKMH 292
DEK+ L QR++++ + L EI + A +R E ESAL + LQ+
Sbjct: 644 DEKETLL--QRLTEVEQERDQL--EIVAMDAENMRKELAELESALQEQHEVNASLQQTQG 699
Query: 293 ECAQLGGELD---RTRDEASRALQRAHEQTETVRKCLQTTV-AELERQLAASRAQVSTAE 348
+ + EL+ RD + L+ E+ + + Q+ + AELE++ A + + A+
Sbjct: 700 DLSAYEAELEARLNLRDAEANQLKEELEKVTRLTQLEQSALQAELEKERQALKNALGKAQ 759
Query: 349 --KEREELKNRLHWQMKRLTEN 368
+E+E+ + LH ++K L ++
Sbjct: 760 FSEEKEQENSELHAKLKHLQDD 781
Score = 30.7 bits (66), Expect = 9.8
Identities = 68/392 (17%), Positives = 155/392 (39%), Gaps = 34/392 (8%)
Query: 17 RCQHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELR 76
+ Q Q ++ L+ + ++L GS QA L++ R E+ E
Sbjct: 1586 KSQVTSQQQEMAVLDRQLGHKKEELHLLQGSMVQAKAD------LQEALRLGETEVTEKC 1639
Query: 77 TLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKL 136
++E L++ + + + E++ Q T I ++I E + +++ ++
Sbjct: 1640 NHIREVKSLLEELSFQKGELNVQISERKTQL-------TLIKQEIEKEEENLQVVLRQMS 1692
Query: 137 QELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTT 196
+ + ++L Q+ + Q + + +L + E+ + +
Sbjct: 1693 KHKTELKNILDMLQLENHELQGLKLQHDQRVSELEKTQVAVLEEKLELENLQQISQQQKG 1752
Query: 197 MTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGD--EKQMALLNQRISQ 254
Q+ L + + EI R + L ++ + D EK++A + ++
Sbjct: 1753 EIEWQKQLLERDKREIERMTAESRALQSCVECLSKEKEDLQEKCDIWEKKLAQTKRVLAA 1812
Query: 255 LAENNISLKSEIERLKASV---------IRTEESALAN-----EKRLQEKMHECAQLGGE 300
EN+ +S +E+L+ +V + ++ +L N +++LQEK L E
Sbjct: 1813 AEENSKMEQSNLEKLELNVRKLQQELDQLNRDKLSLHNDISAMQQQLQEKREAVNSLQEE 1872
Query: 301 LDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHW 360
L +D + A Q T+ + L + L++ ++ + +KE EE K +
Sbjct: 1873 LANVQDHLNLAKQDLLHTTKH-QDVLLSEQTRLQKDISEWANRFEDCQKE-EETKQQ--- 1927
Query: 361 QMKRLTENFEQAQLRILGLQTQVQSLRRTASS 392
Q++ L E+ +L+++ + Q L++ S
Sbjct: 1928 QLQVLQNEIEENKLKLVQQEMMFQRLQKERES 1959
>AK074079-1|BAB84905.1| 1793|Homo sapiens FLJ00150 protein protein.
Length = 1793
Score = 48.4 bits (110), Expect = 5e-05
Identities = 79/391 (20%), Positives = 164/391 (41%), Gaps = 29/391 (7%)
Query: 19 QHRETQNKLRELEMKFEGLAT---HTNMLMGSKEQAFEQEV-----NVRALKQCYREARE 70
+H +N++ LE + L + + SK Q+ E+E+ N+ L Q +
Sbjct: 785 EHHNLENEVSRLEDIMQHLKSKKREERWMRASKRQS-EKEMEELHHNIDDLLQEKKSLEC 843
Query: 71 EIDEL-RTLMKEQNDQ-LQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQI---NLEI 125
E++EL RT+ K Q + D V+ L + +E+ + I + + E+
Sbjct: 844 EVEELHRTVQKRQQQKDFIDGNVESLMTELEIEKSLKHHEDIVDEIECIEKTLLKRRSEL 903
Query: 126 QRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIF 185
+ E EL+ + K + DA+++ E +AE+L R +V
Sbjct: 904 READRLLAEAESELSCTKEKTKNAVEKFTDAKRSLLQTESDAEELERRAQETAVNLVKAD 963
Query: 186 RYLYSLYL----VTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGD 241
+ L SL + + QE++ + + KD L K E+ + D
Sbjct: 964 QQLRSLQADAKDLEQHKIKQEEILKEINKIVAA--KDSDFQCLSKKKEKLTEELQKLQKD 1021
Query: 242 EKQMALLNQ--RISQLAENNISL---KSEIERLKASVIRTEESALANEKRLQEKMHECAQ 296
+MA N+ + L E+ + L ++E+E+LK+ V ++ +++L K E
Sbjct: 1022 I-EMAERNEDHHLQVLKESEVLLQAKRAELEKLKSQVTSQQQEMAVLDRQLGHKKEELHL 1080
Query: 297 LGGELDRTRDEASRALQRAHEQTETVRKCLQ-TTVAELERQLAASRAQVSTAEKEREELK 355
L G + + + + AL+ +TE KC V L +L+ + +++ ER+
Sbjct: 1081 LQGSMVQAKADLQEALRLG--ETEVTEKCNHIREVKSLLEELSFQKGELNVQISERKTQL 1138
Query: 356 NRLHWQMKRLTENFEQAQLRILGLQTQVQSL 386
+ ++++ EN + ++ +T+++++
Sbjct: 1139 TLIKQEIEKEEENLQVVLRQMSKHKTELKNI 1169
Score = 42.7 bits (96), Expect = 0.002
Identities = 83/386 (21%), Positives = 160/386 (41%), Gaps = 49/386 (12%)
Query: 18 CQHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRT 77
C +E ++ + ++ + LA +L ++E + ++ N+ L+ R+ ++E+D+L
Sbjct: 1252 CLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENSKMEQSNLEKLELNVRKLQQELDQLN- 1310
Query: 78 LMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRV--KLKFQEK 135
D+L + QQL +E+R + + +NL Q + K Q+
Sbjct: 1311 -----RDKLSLHNDISAMQQQL-QEKREAVNSLQEELANVQDHLNLAKQDLLHTTKHQDV 1364
Query: 136 L-QELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLV 194
L E + + R +D Q+ + + + L E+ + K+V
Sbjct: 1365 LLSEQTRLQKDISEWANRFEDCQKEEETKQQQLQVLQNEIEENKLKLVQ----------- 1413
Query: 195 TTMTLTQEDLFGQSQSEI-GRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRIS 253
QE +F + Q E +K +T V L EK D+K L+Q +S
Sbjct: 1414 ------QEMMFQRLQKERESEESKLETSKVTLKEQQHQLEKELT---DQKSK--LDQVLS 1462
Query: 254 QL--AENNISLKSEIER----LKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDE 307
++ AE + E ER L+ ++ +T+ E++L EK E L E D R +
Sbjct: 1463 KVLAAEERVRTLQEEERWCESLEKTLSQTKRQLSEREQQLVEKSGELLALQKEADSMRAD 1522
Query: 308 AS-------RALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKER---EELKNR 357
S ++A +Q ++++ L+ ++LE+ L + + S +KE E +
Sbjct: 1523 FSLLRNQFLTERKKAEKQVASLKEALKIQRSQLEKNLLEQKQENSCIQKEMATIELVAQD 1582
Query: 358 LHWQMKRLTENFEQAQLRILGLQTQV 383
H + +RL + Q Q L+ Q+
Sbjct: 1583 NHERARRLMKELNQMQYEYTELKKQM 1608
Score = 34.7 bits (76), Expect = 0.60
Identities = 31/127 (24%), Positives = 63/127 (49%), Gaps = 7/127 (5%)
Query: 242 EKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQE-KMHECAQLGGE 300
EK+ L + Q++++ LK+ ++ L+ + L +++R+ E + + A L +
Sbjct: 1146 EKEEENLQVVLRQMSKHKTELKNILDMLQLENHELQGLKLQHDQRVSELEKTQVAVLEEK 1205
Query: 301 LDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAE---KEREELKNR 357
L+ + + Q+ + E ++ L+ E+ER A SRA S E KE+E+L+ +
Sbjct: 1206 LEL--ENLQQISQQQKGEIEWQKQLLERDKREIERMTAESRALQSCVECLSKEKEDLQEK 1263
Query: 358 LH-WQMK 363
W+ K
Sbjct: 1264 CDIWEKK 1270
Score = 32.3 bits (70), Expect = 3.2
Identities = 37/142 (26%), Positives = 70/142 (49%), Gaps = 18/142 (12%)
Query: 241 DEKQMALLNQRISQLAENNISLKSEIERLKASVIRTE----ESALANEKR----LQEKMH 292
DEK+ L QR++++ + L EI + A +R E ESAL + LQ+
Sbjct: 118 DEKETLL--QRLTEVEQERDQL--EIVAMDAENMRKELAELESALQEQHEVNASLQQTQG 173
Query: 293 ECAQLGGELD---RTRDEASRALQRAHEQTETVRKCLQTTV-AELERQLAASRAQVSTAE 348
+ + EL+ RD + L+ E+ + + Q+ + AELE++ A + + A+
Sbjct: 174 DLSAYEAELEARLNLRDAEANQLKEELEKVTRLTQLEQSALQAELEKERQALKNALGKAQ 233
Query: 349 --KEREELKNRLHWQMKRLTEN 368
+E+E+ + LH ++K L ++
Sbjct: 234 FSEEKEQENSELHAKLKHLQDD 255
Score = 30.7 bits (66), Expect = 9.8
Identities = 68/392 (17%), Positives = 155/392 (39%), Gaps = 34/392 (8%)
Query: 17 RCQHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELR 76
+ Q Q ++ L+ + ++L GS QA L++ R E+ E
Sbjct: 1054 KSQVTSQQQEMAVLDRQLGHKKEELHLLQGSMVQAKAD------LQEALRLGETEVTEKC 1107
Query: 77 TLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKL 136
++E L++ + + + E++ Q T I ++I E + +++ ++
Sbjct: 1108 NHIREVKSLLEELSFQKGELNVQISERKTQL-------TLIKQEIEKEEENLQVVLRQMS 1160
Query: 137 QELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTT 196
+ + ++L Q+ + Q + + +L + E+ + +
Sbjct: 1161 KHKTELKNILDMLQLENHELQGLKLQHDQRVSELEKTQVAVLEEKLELENLQQISQQQKG 1220
Query: 197 MTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGD--EKQMALLNQRISQ 254
Q+ L + + EI R + L ++ + D EK++A + ++
Sbjct: 1221 EIEWQKQLLERDKREIERMTAESRALQSCVECLSKEKEDLQEKCDIWEKKLAQTKRVLAA 1280
Query: 255 LAENNISLKSEIERLKASV---------IRTEESALAN-----EKRLQEKMHECAQLGGE 300
EN+ +S +E+L+ +V + ++ +L N +++LQEK L E
Sbjct: 1281 AEENSKMEQSNLEKLELNVRKLQQELDQLNRDKLSLHNDISAMQQQLQEKREAVNSLQEE 1340
Query: 301 LDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHW 360
L +D + A Q T+ + L + L++ ++ + +KE EE K +
Sbjct: 1341 LANVQDHLNLAKQDLLHTTKH-QDVLLSEQTRLQKDISEWANRFEDCQKE-EETKQQ--- 1395
Query: 361 QMKRLTENFEQAQLRILGLQTQVQSLRRTASS 392
Q++ L E+ +L+++ + Q L++ S
Sbjct: 1396 QLQVLQNEIEENKLKLVQQEMMFQRLQKERES 1427
>AF513978-1|AAP43846.1| 2325|Homo sapiens CENTRIOLIN protein.
Length = 2325
Score = 48.4 bits (110), Expect = 5e-05
Identities = 79/391 (20%), Positives = 164/391 (41%), Gaps = 29/391 (7%)
Query: 19 QHRETQNKLRELEMKFEGLAT---HTNMLMGSKEQAFEQEV-----NVRALKQCYREARE 70
+H +N++ LE + L + + SK Q+ E+E+ N+ L Q +
Sbjct: 1317 EHHNLENEVSRLEDIMQHLKSKKREERWMRASKRQS-EKEMEELHHNIDDLLQEKKSLEC 1375
Query: 71 EIDEL-RTLMKEQNDQ-LQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQI---NLEI 125
E++EL RT+ K Q + D V+ L + +E+ + I + + E+
Sbjct: 1376 EVEELHRTVQKRQQQKDFIDGNVESLMTELEIEKSLKHHEDIVDEIECIEKTLLKRRSEL 1435
Query: 126 QRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIF 185
+ E EL+ + K + DA+++ E +AE+L R +V
Sbjct: 1436 READRLLAEAESELSCTKEKTKNAVEKFTDAKRSLLQTESDAEELERRAQETAVNLVKAD 1495
Query: 186 RYLYSLYL----VTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGD 241
+ L SL + + QE++ + + KD L K E+ + D
Sbjct: 1496 QQLRSLQADAKDLEQHKIKQEEILKEINKIVAA--KDSDFQCLSKKKEKLTEELQKLQKD 1553
Query: 242 EKQMALLNQ--RISQLAENNISL---KSEIERLKASVIRTEESALANEKRLQEKMHECAQ 296
+MA N+ + L E+ + L ++E+E+LK+ V ++ +++L K E
Sbjct: 1554 I-EMAERNEDHHLQVLKESEVLLQAKRAELEKLKSQVTSQQQEMAVLDRQLGHKKEELHL 1612
Query: 297 LGGELDRTRDEASRALQRAHEQTETVRKCLQ-TTVAELERQLAASRAQVSTAEKEREELK 355
L G + + + + AL+ +TE KC V L +L+ + +++ ER+
Sbjct: 1613 LQGSMVQAKADLQEALRLG--ETEVTEKCNHIREVKSLLEELSFQKGELNVQISERKTQL 1670
Query: 356 NRLHWQMKRLTENFEQAQLRILGLQTQVQSL 386
+ ++++ EN + ++ +T+++++
Sbjct: 1671 TLIKQEIEKEEENLQVVLRQMSKHKTELKNI 1701
Score = 42.7 bits (96), Expect = 0.002
Identities = 83/386 (21%), Positives = 160/386 (41%), Gaps = 49/386 (12%)
Query: 18 CQHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRT 77
C +E ++ + ++ + LA +L ++E + ++ N+ L+ R+ ++E+D+L
Sbjct: 1784 CLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENSKMEQSNLEKLELNVRKLQQELDQLN- 1842
Query: 78 LMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRV--KLKFQEK 135
D+L + QQL +E+R + + +NL Q + K Q+
Sbjct: 1843 -----RDKLSLHNDISAMQQQL-QEKREAVNSLQEELANVQDHLNLAKQDLLHTTKHQDV 1896
Query: 136 L-QELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLV 194
L E + + R +D Q+ + + + L E+ + K+V
Sbjct: 1897 LLSEQTRLQKDISEWANRFEDCQKEEETKQQQLQVLQNEIEENKLKLVQ----------- 1945
Query: 195 TTMTLTQEDLFGQSQSEI-GRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRIS 253
QE +F + Q E +K +T V L EK D+K L+Q +S
Sbjct: 1946 ------QEMMFQRLQKERESEESKLETSKVTLKEQQHQLEKELT---DQKSK--LDQVLS 1994
Query: 254 QL--AENNISLKSEIER----LKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDE 307
++ AE + E ER L+ ++ +T+ E++L EK E L E D R +
Sbjct: 1995 KVLAAEERVRTLQEEERWCESLEKTLSQTKRQLSEREQQLVEKSGELLALQKEADSMRAD 2054
Query: 308 AS-------RALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKER---EELKNR 357
S ++A +Q ++++ L+ ++LE+ L + + S +KE E +
Sbjct: 2055 FSLLRNQFLTERKKAEKQVASLKEALKIQRSQLEKNLLEQKQENSCIQKEMATIELVAQD 2114
Query: 358 LHWQMKRLTENFEQAQLRILGLQTQV 383
H + +RL + Q Q L+ Q+
Sbjct: 2115 NHERARRLMKELNQMQYEYTELKKQM 2140
Score = 34.7 bits (76), Expect = 0.60
Identities = 31/127 (24%), Positives = 63/127 (49%), Gaps = 7/127 (5%)
Query: 242 EKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQE-KMHECAQLGGE 300
EK+ L + Q++++ LK+ ++ L+ + L +++R+ E + + A L +
Sbjct: 1678 EKEEENLQVVLRQMSKHKTELKNILDMLQLENHELQGLKLQHDQRVSELEKTQVAVLEEK 1737
Query: 301 LDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAE---KEREELKNR 357
L+ + + Q+ + E ++ L+ E+ER A SRA S E KE+E+L+ +
Sbjct: 1738 LEL--ENLQQISQQQKGEIEWQKQLLERDKREIERMTAESRALQSCVECLSKEKEDLQEK 1795
Query: 358 LH-WQMK 363
W+ K
Sbjct: 1796 CDIWEKK 1802
Score = 32.3 bits (70), Expect = 3.2
Identities = 37/142 (26%), Positives = 70/142 (49%), Gaps = 18/142 (12%)
Query: 241 DEKQMALLNQRISQLAENNISLKSEIERLKASVIRTE----ESALANEKR----LQEKMH 292
DEK+ L QR++++ + L EI + A +R E ESAL + LQ+
Sbjct: 644 DEKETLL--QRLTEVEQERDQL--EIVAMDAENMRKELAELESALQEQHEVNASLQQTQG 699
Query: 293 ECAQLGGELD---RTRDEASRALQRAHEQTETVRKCLQTTV-AELERQLAASRAQVSTAE 348
+ + EL+ RD + L+ E+ + + Q+ + AELE++ A + + A+
Sbjct: 700 DLSAYEAELEARLNLRDAEANQLKEELEKVTRLTQLEQSALQAELEKERQALKNALGKAQ 759
Query: 349 --KEREELKNRLHWQMKRLTEN 368
+E+E+ + LH ++K L ++
Sbjct: 760 FSEEKEQENSELHAKLKHLQDD 781
Score = 30.7 bits (66), Expect = 9.8
Identities = 68/392 (17%), Positives = 155/392 (39%), Gaps = 34/392 (8%)
Query: 17 RCQHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELR 76
+ Q Q ++ L+ + ++L GS QA L++ R E+ E
Sbjct: 1586 KSQVTSQQQEMAVLDRQLGHKKEELHLLQGSMVQAKAD------LQEALRLGETEVTEKC 1639
Query: 77 TLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKL 136
++E L++ + + + E++ Q T I ++I E + +++ ++
Sbjct: 1640 NHIREVKSLLEELSFQKGELNVQISERKTQL-------TLIKQEIEKEEENLQVVLRQMS 1692
Query: 137 QELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTT 196
+ + ++L Q+ + Q + + +L + E+ + +
Sbjct: 1693 KHKTELKNILDMLQLENHELQGLKLQHDQRVSELEKTQVAVLEEKLELENLQQISQQQKG 1752
Query: 197 MTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGD--EKQMALLNQRISQ 254
Q+ L + + EI R + L ++ + D EK++A + ++
Sbjct: 1753 EIEWQKQLLERDKREIERMTAESRALQSCVECLSKEKEDLQEKCDIWEKKLAQTKRVLAA 1812
Query: 255 LAENNISLKSEIERLKASV---------IRTEESALAN-----EKRLQEKMHECAQLGGE 300
EN+ +S +E+L+ +V + ++ +L N +++LQEK L E
Sbjct: 1813 AEENSKMEQSNLEKLELNVRKLQQELDQLNRDKLSLHNDISAMQQQLQEKREAVNSLQEE 1872
Query: 301 LDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHW 360
L +D + A Q T+ + L + L++ ++ + +KE EE K +
Sbjct: 1873 LANVQDHLNLAKQDLLHTTKH-QDVLLSEQTRLQKDISEWANRFEDCQKE-EETKQQ--- 1927
Query: 361 QMKRLTENFEQAQLRILGLQTQVQSLRRTASS 392
Q++ L E+ +L+++ + Q L++ S
Sbjct: 1928 QLQVLQNEIEENKLKLVQQEMMFQRLQKERES 1959
>AF155135-1|AAF44722.1| 980|Homo sapiens novel retinal pigment
epithelial cell protein protein.
Length = 980
Score = 48.4 bits (110), Expect = 5e-05
Identities = 42/178 (23%), Positives = 87/178 (48%), Gaps = 13/178 (7%)
Query: 21 RETQNKLRE-LEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLM 79
R + KL+ LE + LA+ + KE+ + V +R+ + + E + ++TL+
Sbjct: 786 RSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIRSEVS---QVKREKENIQTLL 842
Query: 80 KEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQEL 139
K + ++ + K+ QAQ+ + E +R ++IN E+ + K +E L L
Sbjct: 843 KSKEQEVNELLQKFQQAQEELAEMKRYAESSSKLEEDKDKKIN-EMSKEVTKLKEALNSL 901
Query: 140 APIPDLLKATQMRLKDAQQAQAIAEHNAEQLAREL-NCAR--EKVVHIFRYLYSLYLV 194
+ L +T + +QQ +A+ + +QL +L C + ++V+ ++R ++ LY V
Sbjct: 902 S---QLSYSTSSSKRQSQQLEAL-QQQVKQLQNQLAECKKQHQEVISVYR-MHLLYAV 954
Score = 44.0 bits (99), Expect = 0.001
Identities = 75/350 (21%), Positives = 152/350 (43%), Gaps = 45/350 (12%)
Query: 65 YREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLE 124
Y+EA+EEI +L+ +K Q Q +A E+ + R+ +++N +
Sbjct: 601 YQEAQEEIMKLKDTLKSQMTQ---------EASDEAEDMKE-------AMNRMIDELNKQ 644
Query: 125 IQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHI 184
+ + ++E EL D K + A+ AEH E+L + N +R K
Sbjct: 645 VSELSQLYKEAQAEL---EDYRKRKSLEDVTAEYIHK-AEH--EKLMQLTNVSRAKAEDA 698
Query: 185 FRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQ 244
+ S Y LTQ +Q E + T H+ + +L+ K E +
Sbjct: 699 LSEMKSQYSKVLNELTQLKQLVDAQKE---NSVSITEHLQVITTLRTAAKEMEEKISNLK 755
Query: 245 MALLNQRI------SQLAENNISL------KSEIERLKASVIRTEESALANEKRLQEKMH 292
L ++ + QL E ++ +S E+L++S + +E S LA+ +L+E +
Sbjct: 756 EHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSS-LESEVSVLAS--KLKESVK 812
Query: 293 ECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKERE 352
E ++ E+ + R E S+ ++R E +T+ K + V EL ++ ++ +++ ++ E
Sbjct: 813 EKEKVHSEVVQIRSEVSQ-VKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYAE 871
Query: 353 ELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRRTASSTGDGDGENQE 402
+ K++ E ++ + L+ + SL + + ST ++Q+
Sbjct: 872 SSSKLEEDKDKKINEMSKE----VTKLKEALNSLSQLSYSTSSSKRQSQQ 917
Score = 32.7 bits (71), Expect = 2.4
Identities = 53/304 (17%), Positives = 124/304 (40%), Gaps = 18/304 (5%)
Query: 53 EQEVNVRALKQCYREAREEIDELRT-----------LMKEQNDQL-QDYRVKYLQAQQLV 100
E V L Q Y+EA+ E+++ R + K ++++L Q V +A+ +
Sbjct: 640 ELNKQVSELSQLYKEAQAELEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDAL 699
Query: 101 EEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQ 160
E + Q T++ + ++ + + + E LQ + + K + ++ + ++
Sbjct: 700 SEMKSQYSKVLNELTQLKQLVDAQKEN-SVSITEHLQVITTLRTAAKEMEEKISNLKEHL 758
Query: 161 AIAEHNAEQLARELNCAREKVVHIFRYL-YSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQ 219
A E +L ++L EK + S Y +L E S+ + K++
Sbjct: 759 ASKEVEVAKLEKQL--LEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEK 816
Query: 220 TVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEES 279
++ + + E+ + + Q +++L + + E+ +K + +
Sbjct: 817 VHSEVVQIRSEVSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYAESSSKL 876
Query: 280 ALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAA 339
+K++ E E +L L+ + + S + + Q++ + + LQ V +L+ QLA
Sbjct: 877 EEDKDKKINEMSKEVTKLKEALN-SLSQLSYSTSSSKRQSQQL-EALQQQVKQLQNQLAE 934
Query: 340 SRAQ 343
+ Q
Sbjct: 935 CKKQ 938
>AB201172-1|BAE44387.1| 1870|Homo sapiens girdin protein.
Length = 1870
Score = 48.4 bits (110), Expect = 5e-05
Identities = 61/350 (17%), Positives = 151/350 (43%), Gaps = 23/350 (6%)
Query: 42 NMLMGSKEQAFEQEV--NVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQL 99
N + K + E E+ ++L+ C +++ + E + +++ + L++ + ++ +
Sbjct: 500 NQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKE-KAQLEKTIETLRENSERQIKILEQ 558
Query: 100 VEEQRRQXXXXXXXNTRISEQINL-EIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQ 158
E Q ++IS + + +I++ E ++E + ++ + ++K +
Sbjct: 559 ENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELE 618
Query: 159 AQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKD 218
AE+L EL+ ++ + + + +L + T + + Q SE+ R N+
Sbjct: 619 HYKEKGERAEELENELHHLEKENELLQKKITNLKI----TCEKIEALEQENSELERENRK 674
Query: 219 QTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEE 278
+ +L Q+ L + SQL E N+ L+ +E LK + ++ +
Sbjct: 675 LKKTLDSFKNLT------------FQLESLEKENSQLDEENLELRRNVESLKCASMKMAQ 722
Query: 279 SALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLA 338
L N++ EK E + G EL + + + L+ +++ + + LQ T+ +++
Sbjct: 723 LQLENKELESEK--EQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQ 780
Query: 339 ASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRR 388
+++ E E + L+ L ++K ++ EQ + L+ + L +
Sbjct: 781 QLESELQDLEMENQTLQKNLE-ELKISSKRLEQLEKENKSLEQETSQLEK 829
Score = 44.4 bits (100), Expect = 7e-04
Identities = 73/383 (19%), Positives = 162/383 (42%), Gaps = 28/383 (7%)
Query: 22 ETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKE 81
+ Q + +ELE + E L +L S ++ EV+ + L + ++ ++ +++
Sbjct: 722 QLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQ 781
Query: 82 QNDQLQDYRVKYLQAQQLVEEQR--RQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQEL 139
+LQD ++ Q+ +EE + + + EQ ++++ K + +++ + L
Sbjct: 782 LESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRL 841
Query: 140 APIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHI------FRYLYSLYL 193
++ T L++ E + L++E+ +E V + + L
Sbjct: 842 RQQAEIKDTT---LEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRAT 898
Query: 194 VTTMTLT--QEDLFGQS-QSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQ 250
+ TL +EDL + +++ + ++ H L L + + + LL
Sbjct: 899 IDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLES 958
Query: 251 RISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASR 310
++ + ++ +K E++ A R EES N++ QE + + E + R + R
Sbjct: 959 KLESTLKKSLEIKE--EKIAALEARLEESTNYNQQLRQEL--KTVKKNYEALKQRQDEER 1014
Query: 311 ALQR----AHEQTETVRKCLQTT--VAELERQLAASRAQVSTAEKEREELKNRLHWQMKR 364
+Q + E + R+ +TT + +++ +L +T + E++ LK Q+K+
Sbjct: 1015 MVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKT----QLKQ 1070
Query: 365 LTENFEQAQLRILGLQTQVQSLR 387
L Q +IL LQ Q SL+
Sbjct: 1071 LETQNNNLQAQILALQRQTVSLQ 1093
>AB125644-1|BAF44475.1| 1843|Homo sapiens PKB/Akt-binding protein
protein.
Length = 1843
Score = 48.4 bits (110), Expect = 5e-05
Identities = 61/350 (17%), Positives = 151/350 (43%), Gaps = 23/350 (6%)
Query: 42 NMLMGSKEQAFEQEV--NVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQL 99
N + K + E E+ ++L+ C +++ + E + +++ + L++ + ++ +
Sbjct: 500 NQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKE-KAQLEKTIETLRENSERQIKILEQ 558
Query: 100 VEEQRRQXXXXXXXNTRISEQINL-EIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQ 158
E Q ++IS + + +I++ E ++E + ++ + ++K +
Sbjct: 559 ENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELE 618
Query: 159 AQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKD 218
AE+L EL+ ++ + + + +L + T + + Q SE+ R N+
Sbjct: 619 HYKEKGERAEELENELHHLEKENELLQKKITNLKI----TCEKIEALEQENSELERENRK 674
Query: 219 QTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEE 278
+ +L Q+ L + SQL E N+ L+ +E LK + ++ +
Sbjct: 675 LKKTLDSFKNLT------------FQLESLEKENSQLDEENLELRRNVESLKCASMKMAQ 722
Query: 279 SALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLA 338
L N++ EK E + G EL + + + L+ +++ + + LQ T+ +++
Sbjct: 723 LQLENKELESEK--EQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQ 780
Query: 339 ASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRR 388
+++ E E + L+ L ++K ++ EQ + L+ + L +
Sbjct: 781 QLESELQDLEMENQTLQKNLE-ELKISSKRLEQLEKENKSLEQETSQLEK 829
Score = 46.0 bits (104), Expect = 2e-04
Identities = 76/384 (19%), Positives = 165/384 (42%), Gaps = 29/384 (7%)
Query: 22 ETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKE 81
+ Q + +ELE + E L +L S ++ EV+ + L + ++ ++ +++
Sbjct: 722 QLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQ 781
Query: 82 QNDQLQDYRVKYLQAQQLVEEQR--RQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQEL 139
+LQD ++ Q+ +EE + + + EQ ++++ K + +++ + L
Sbjct: 782 LESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRL 841
Query: 140 APIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHI------FRYLYSLYL 193
++ T L++ E + L++E+ +E V + + L
Sbjct: 842 RQQAEIKDTT---LEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRAT 898
Query: 194 VTTMTLT--QEDLFGQS-QSEIGRGNKDQTVHVLLHNSL-KPPEKPPERGGDEKQMALLN 249
+ TL +EDL + +++ + ++ H L L K E+ D+ + LL
Sbjct: 899 IDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLE 958
Query: 250 QRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEAS 309
++ + ++ +K E++ A R EES N++ QE + + E + R +
Sbjct: 959 SKLESTLKKSLEIKE--EKIAALEARLEESTNYNQQLRQEL--KTVKKNYEALKQRQDEE 1014
Query: 310 RALQR----AHEQTETVRKCLQTT--VAELERQLAASRAQVSTAEKEREELKNRLHWQMK 363
R +Q + E + R+ +TT + +++ +L +T + E++ LK Q+K
Sbjct: 1015 RMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKT----QLK 1070
Query: 364 RLTENFEQAQLRILGLQTQVQSLR 387
+L Q +IL LQ Q SL+
Sbjct: 1071 QLETQNNNLQAQILALQRQTVSLQ 1094
Score = 32.7 bits (71), Expect = 2.4
Identities = 67/353 (18%), Positives = 151/353 (42%), Gaps = 27/353 (7%)
Query: 26 KLRELEMKFEGLATHTNMLMGSKEQAFEQ----EVNVRALKQCYREAREEIDELRTLMKE 81
K LE+ ++GL L + E + ++ E ++ L+ + ++ ++EL+ + +
Sbjct: 750 KTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELK-ISSK 808
Query: 82 QNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISE--QINLEIQRVKLKFQEKLQE- 138
+ +QL+ Q +E+ ++Q + +E LE VK+ EK +
Sbjct: 809 RLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKT 868
Query: 139 LAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMT 198
L+ + K + +RLK+ ++ A + L RE +V L + + +
Sbjct: 869 LSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVS--EKLKTQQMNNDLE 926
Query: 199 -LTQE-DLFGQSQSEI--GRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQ 254
LT E + G ++ + + D + + LL + L+ K +EK +A L R+ +
Sbjct: 927 KLTHELEKIGLNKERLLHDEQSTDDSRYKLLESKLESTLKKSLEIKEEK-IAALEARLEE 985
Query: 255 LAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRAL-- 312
N L+ E++ +K + ++ +E+R+ + + + +R E +R L
Sbjct: 986 STNYNQQLRQELKTVKKNYEALKQRQ--DEERMVQSSPPISGEDNKWERESQETTRELLK 1043
Query: 313 --------QRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNR 357
+R + + ++ L+T + +LE Q +AQ+ +++ L+ +
Sbjct: 1044 VKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQ 1096
>AB111886-1|BAC98374.1| 1571|Homo sapiens KIAA2034 protein protein.
Length = 1571
Score = 48.4 bits (110), Expect = 5e-05
Identities = 67/319 (21%), Positives = 139/319 (43%), Gaps = 27/319 (8%)
Query: 67 EAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQ 126
+ R+E+++L+ + ++ +LQ+ V + QQ EE R Q R E++ +
Sbjct: 641 KGRQELEKLKRRLDGESSELQEQMV---EQQQRAEELRAQLG-------RKEEELQAALA 690
Query: 127 RVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFR 186
R + + + Q L + + A +D + ++ +A AE+ R+L E +
Sbjct: 691 RAEDEGGARAQLLKSLREAQAALAEAQEDLE-SERVARTKAEKQRRDLGEELEALRG--- 746
Query: 187 YLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPP--EKPPERGGD-EK 243
L T Q++L + + E+ K +H + ++ + G+ +
Sbjct: 747 ---ELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAE 803
Query: 244 QMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANE---KRLQEKMHECAQLGGE 300
Q+ + + ++L++E+ L+A + + + E +RL+ ++ E G+
Sbjct: 804 QLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGD 863
Query: 301 LDRTRDEASRALQRAHEQTETVRKCL---QTTVAELERQLAASRAQVSTA-EKEREELKN 356
+R R EA+ LQRA + E V L ++ L ++L+++ AQ+ A E +EE +
Sbjct: 864 GERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRA 923
Query: 357 RLHWQMKRLTENFEQAQLR 375
+L + E A LR
Sbjct: 924 KLALGSRVRAMEAEAAGLR 942
Score = 42.3 bits (95), Expect = 0.003
Identities = 67/318 (21%), Positives = 128/318 (40%), Gaps = 22/318 (6%)
Query: 53 EQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXX 112
E+ V L++ R ++E+D+ +++Q + K + QL+ E++
Sbjct: 1003 EKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVE 1062
Query: 113 XNTRIS------EQINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHN 166
R E L + R + QE +EL L+A L ++ + H
Sbjct: 1063 ERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHE 1122
Query: 167 AEQLAR----ELNCAREKVVHIFRYLYSLY-LVTTMTLTQEDLFGQSQSEI-GRGNKDQT 220
E+ R N R +V + L + + +T + L Q + ++ GR +
Sbjct: 1123 LERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEE 1182
Query: 221 VHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESA 280
L L+ E ER + KQ L +A L+ E+E LKA + +
Sbjct: 1183 RRRQLAKQLRDAEV--ERDEERKQRTLA------VAARK-KLEGELEELKAQMASAGQGK 1233
Query: 281 LANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAAS 340
K+L++ + +L E++ TR + + ++E K L+ V L+ +LAAS
Sbjct: 1234 EEAVKQLRKMQAQMKELWREVEETRTSREEIFSQ-NRESEKRLKGLEAEVLRLQEELAAS 1292
Query: 341 RAQVSTAEKEREELKNRL 358
A+++R+E+ + +
Sbjct: 1293 DRARRQAQQDRDEMADEV 1310
Score = 40.3 bits (90), Expect = 0.012
Identities = 71/369 (19%), Positives = 152/369 (41%), Gaps = 32/369 (8%)
Query: 22 ETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKE 81
E Q ELE + L L+ SK+ + +V L++ R A + ++LR + E
Sbjct: 1087 EEQEAREELERQNRALRAELEALLSSKDDVGK---SVHELERACRVAEQAANDLRAQVTE 1143
Query: 82 QNDQL---QDYRVKY-LQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQ 137
D+L +D +++ + Q L + R Q+ +++ +++ E+ +
Sbjct: 1144 LEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERK 1203
Query: 138 ELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTM 197
+ K + L++ + A A E+ ++L + ++ ++R + T
Sbjct: 1204 QRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEE-----TR 1258
Query: 198 TLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGG-DEKQMA--LLNQRISQ 254
T ++E++F Q++ R + + L L ++ + D +MA + N +S+
Sbjct: 1259 T-SREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSK 1317
Query: 255 LA--ENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRA- 311
A E L+ + +L+ + + ++ R ++ + + L EL R +++A
Sbjct: 1318 AAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAE 1377
Query: 312 --LQRAHEQTETVRKCL-----------QTTVAELERQLAASRAQVSTAEKEREELKNRL 358
Q+ Q + +R L + T+A LE +LA + Q+ +ER +
Sbjct: 1378 SGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLV 1437
Query: 359 HWQMKRLTE 367
KRL E
Sbjct: 1438 RRAEKRLKE 1446
Score = 37.1 bits (82), Expect = 0.11
Identities = 78/353 (22%), Positives = 155/353 (43%), Gaps = 33/353 (9%)
Query: 39 THTNMLMGSKEQAFEQEV-NVRALKQCYREAREEID-ELRTLMKEQND--QLQDYRVKYL 94
T + +GS+ +A E E +R + ARE EL+T + ++ + Q+ L
Sbjct: 921 TRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGAL 980
Query: 95 QAQQLVEEQRRQXXXXXXXNTRISEQINL--EIQRVKLKFQEKLQELAPIPDLLKATQMR 152
+A + E +RR R++E+ ++R + + Q++L + + +
Sbjct: 981 EAGE--EARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVST 1038
Query: 153 LKDAQQA--QAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQS 210
L+ Q+ Q +AE A L R + RE+ R + L T L +E +++
Sbjct: 1039 LEKKQRKFDQLLAEEKAAVL-RAVE-ERERAEAEGREREARALSLTRALEEEQ---EARE 1093
Query: 211 EIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLK 270
E+ R N+ + +L + + E + A R+++ A N+ L++++ L+
Sbjct: 1094 ELERQNRALRAEL---EALLSSKDDVGKSVHELERAC---RVAEQAAND--LRAQVTELE 1145
Query: 271 ASVIRTEESALANEKRLQ--EKMHECAQLGGEL--DRTRDEASRALQRAHEQTETVRKCL 326
+ E++ L E +Q + HE G + + R + ++ L+ A + + RK
Sbjct: 1146 DELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQR 1205
Query: 327 QTTVA---ELERQLAASRAQVSTAEKEREELKNRL---HWQMKRLTENFEQAQ 373
VA +LE +L +AQ+++A + +EE +L QMK L E+ +
Sbjct: 1206 TLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETR 1258
Score = 36.7 bits (81), Expect = 0.15
Identities = 63/346 (18%), Positives = 143/346 (41%), Gaps = 13/346 (3%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKE----QAFEQEVNVRALKQCYREAREEIDE 74
+ R+ +LR+ E++ + + + +++ + E + + + Q EA +++ +
Sbjct: 1183 RRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRK 1242
Query: 75 LRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQE 134
++ MKE ++++ R + E ++ R+ E++ R + + Q+
Sbjct: 1243 MQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAAS-DRARRQAQQ 1301
Query: 135 KLQELAP-IPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYL 193
E+A + + + L++ +Q + E+L E + + E + +R L
Sbjct: 1302 DRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNS-ELLNDRYRKLLLQVE 1360
Query: 194 VTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRIS 253
T L+ E F +++E GR ++ + L E R + +A L +++
Sbjct: 1361 SLTTELSAERSFS-AKAESGRQQLERQIQEL--RGRLGEEDAGARARHKMTIAALESKLA 1417
Query: 254 QLAENNISLKSEIERLKASVIRTEESALANEK-RLQEKMHECAQLGGELDRTRDEASRAL 312
Q AE + ++ L ++R E L +++E+ QL +L++ + L
Sbjct: 1418 Q-AEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQ-L 1475
Query: 313 QRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRL 358
+R E+ E Q L+R+L + +E L+NRL
Sbjct: 1476 KRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRL 1521
>AB040945-1|BAA96036.2| 2010|Homo sapiens KIAA1512 protein protein.
Length = 2010
Score = 48.4 bits (110), Expect = 5e-05
Identities = 75/335 (22%), Positives = 135/335 (40%), Gaps = 31/335 (9%)
Query: 35 EGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYL 94
E LA L G + E + L++ + +E ++L ++ + D L D +
Sbjct: 923 EELAALRAELRGLRGALAAAEAKRQELEETHVSITQEKNDLALQLQAEQDNLADAEER-- 980
Query: 95 QAQQLVEEQRRQXXXXXXXNTRIS--EQINLEIQRVKLKFQEKLQELAPIPDLLKATQMR 152
L++ + + + R+ E++N ++ + K +++ EL D L+ T +
Sbjct: 981 -CHLLIKSKVQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTELKKDIDDLELTLAK 1039
Query: 153 LKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEI 212
+ +QA E+ + L E+ E V + + +L L G Q+E
Sbjct: 1040 AEKEKQA---TENKVKNLTEEMAALDESVARLTKEKKALQEAHQQAL------GDLQAEE 1090
Query: 213 GRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKAS 272
R + + L ++ E E+ EK++ + +R + E ++ L E S
Sbjct: 1091 DRVSALTKAKLRLEQQVEDLECSLEQ---EKKLRMDTERAKRKLEGDLKLTQE------S 1141
Query: 273 VIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAE 332
V + E++L++K E +QL R DE Q Q + K LQ E
Sbjct: 1142 VADAAQDKQQLEEKLKKKDSELSQLSL---RVEDE-----QLLGAQMQKKIKELQARAEE 1193
Query: 333 LERQLAASRAQVSTAEKEREELKNRLHWQMKRLTE 367
LE +L A RA + EK+R E L +RL E
Sbjct: 1194 LEEELEAERAARARVEKQRAEAARELEELSERLEE 1228
Score = 37.9 bits (84), Expect = 0.065
Identities = 84/387 (21%), Positives = 152/387 (39%), Gaps = 34/387 (8%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTL 78
+ + T+NK++ L + L L +KE+ QE + +AL E + + L
Sbjct: 1043 EKQATENKVKNLTEEMAALDESVARL--TKEKKALQEAHQQALGDLQAE-EDRVSALTKA 1099
Query: 79 MKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQE 138
Q++D Q ++L + R + +++++ + + K + +EKL++
Sbjct: 1100 KLRLEQQVEDLECSLEQEKKLRMDTER-AKRKLEGDLKLTQESVADAAQDKQQLEEKLKK 1158
Query: 139 L-APIPDL-LKATQMRLKDAQQAQAIAE--HNAEQLARELNCAREKVVHIFRY-LYSLYL 193
+ + L L+ +L AQ + I E AE+L EL R + + +
Sbjct: 1159 KDSELSQLSLRVEDEQLLGAQMQKKIKELQARAEELEEELEAERAARARVEKQRAEAARE 1218
Query: 194 VTTMTLTQEDLFGQS----------QSEIGRGNKDQTVHVLLHNSLKPP--EKPPERGGD 241
+ ++ E+ G S ++E+GR ++ L H + K E +
Sbjct: 1219 LEELSERLEEAGGASAGQREGCRKREAELGRLRRELEEAALRHEATVAALRRKQAEGAAE 1278
Query: 242 EKQMALLNQRISQLAENNIS-LKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGE 300
+ QR+ Q E S L+ E++ L A+V L K EK+ C +
Sbjct: 1279 LGEQVDSLQRVRQKLEKEKSELRMEVDDLAANV-----ETLTRAKASAEKL--CRTYEDQ 1331
Query: 301 LDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHW 360
L + + LQR T R LQT EL R L +S + + L
Sbjct: 1332 LSEAKIKVEE-LQRQLADASTQRGRLQTESGELSRLLEEKECLISQLSRGKALAAQSLE- 1389
Query: 361 QMKRLTENFEQAQLRILGLQTQVQSLR 387
+++R E +A+ L VQ+LR
Sbjct: 1390 ELRRQLEEESKAK---SALAHAVQALR 1413
Score = 35.9 bits (79), Expect = 0.26
Identities = 73/352 (20%), Positives = 135/352 (38%), Gaps = 31/352 (8%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTL 78
Q + Q+ L + E + L L G ++ E+ + + R ++++ T
Sbjct: 966 QLQAEQDNLADAEERCHLLIKSKVQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTE 1025
Query: 79 MKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQE 138
+K+ D L+ K + +Q E + + + E + + + K QE Q+
Sbjct: 1026 LKKDIDDLELTLAKAEKEKQATENKVKNLTEEMAA---LDESV-ARLTKEKKALQEAHQQ 1081
Query: 139 LAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMT 198
+ DL +A + R+ +A+ E E L E + +EK + + L +
Sbjct: 1082 A--LGDL-QAEEDRVSALTKAKLRLEQQVEDL--ECSLEQEKKLRMDTERAKRKLEGDLK 1136
Query: 199 LTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQM-ALLNQRISQLAE 257
LTQE + +Q + Q + L + R DE+ + A + ++I +L
Sbjct: 1137 LTQESVADAAQDK-------QQLEEKLKKKDSELSQLSLRVEDEQLLGAQMQKKIKELQA 1189
Query: 258 NNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGG--------------ELDR 303
L+ E+E +A+ R E+ + L+E + GG EL R
Sbjct: 1190 RAEELEEELEAERAARARVEKQRAEAARELEELSERLEEAGGASAGQREGCRKREAELGR 1249
Query: 304 TRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELK 355
R E A R +R+ AEL Q+ + + EKE+ EL+
Sbjct: 1250 LRRELEEAALRHEATVAALRRKQAEGAAELGEQVDSLQRVRQKLEKEKSELR 1301
Score = 34.7 bits (76), Expect = 0.60
Identities = 67/308 (21%), Positives = 115/308 (37%), Gaps = 25/308 (8%)
Query: 92 KYLQAQQLVEEQRRQXXXXXX---XNTRISEQINLEIQRVKLKFQEKLQELAPIPDLLKA 148
K ++ +EE+RRQ R S + E+ R++ +E L+ L + K
Sbjct: 1521 KQRHLERALEERRRQEEEMQRELEAAQRESRGLGTELFRLRHGHEEALEALETLKRENKN 1580
Query: 149 TQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLY----SLYLVTTMTLTQEDL 204
Q + D +++ + ++L + + I L +L L T TL +
Sbjct: 1581 LQEEISDLTDQVSLSGKSIQELEKTKKALEGEKSEIQAALEEAEGALELEETKTLRIQLE 1640
Query: 205 FGQSQSEIGR--GNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISL 262
Q ++E+ R KD+ L N + E E + R+ + E +++
Sbjct: 1641 LSQVKAEVDRKLAEKDEECANLRRNHQRAVESLQASLDAETRARNEALRLKKKMEGDLN- 1699
Query: 263 KSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETV 322
++E R A A + +Q ++ E Q G RDE R HEQ + +
Sbjct: 1700 --DLELQLGHATRQATEAQAATRLMQAQLKE-EQAG------RDEEQRLAAELHEQAQAL 1750
Query: 323 RKCLQTTVAELERQLAA------SRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQLRI 376
+ AELE AA SR E E N LH Q L ++ + +
Sbjct: 1751 ERRASLLAAELEELRAALEQGERSRRLAEQELLEATERLNLLHSQNTGLLNQKKKLEADL 1810
Query: 377 LGLQTQVQ 384
L +V+
Sbjct: 1811 AQLSGEVE 1818
Score = 31.5 bits (68), Expect = 5.6
Identities = 35/148 (23%), Positives = 65/148 (43%), Gaps = 15/148 (10%)
Query: 24 QNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALK-QCYREAREEIDELRTLMKEQ 82
+ +REL+ + E L G K+Q + E VR L+ + E ++ + L+ + K +
Sbjct: 1863 EQTVRELQARLE--EAEQAALRGGKKQVQKLEAKVRELEAELDAEQKKHAEALKGVRKHE 1920
Query: 83 NDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPI 142
RVK L Q EE R+ + +++ +++ K +F+E Q+
Sbjct: 1921 R------RVKELAYQ--AEEDRKNLARMQD----LVDKLQSKVKSYKRQFEEAEQQANTN 1968
Query: 143 PDLLKATQMRLKDAQQAQAIAEHNAEQL 170
+ Q L DA++ +AE A +L
Sbjct: 1969 LAKYRKAQHELDDAEERADMAETQANKL 1996
>AB037755-1|BAA92572.1| 989|Homo sapiens KIAA1334 protein protein.
Length = 989
Score = 48.4 bits (110), Expect = 5e-05
Identities = 42/178 (23%), Positives = 87/178 (48%), Gaps = 13/178 (7%)
Query: 21 RETQNKLRE-LEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLM 79
R + KL+ LE + LA+ + KE+ + V +R+ + + E + ++TL+
Sbjct: 795 RSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIRSEVS---QVKREKENIQTLL 851
Query: 80 KEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQEL 139
K + ++ + K+ QAQ+ + E +R ++IN E+ + K +E L L
Sbjct: 852 KSKEQEVNELLQKFQQAQEELAEMKRYSESSSKLEEDKDKKIN-EMSKEVTKLKEALNSL 910
Query: 140 APIPDLLKATQMRLKDAQQAQAIAEHNAEQLAREL-NCAR--EKVVHIFRYLYSLYLV 194
+ L +T + +QQ +A+ + +QL +L C + ++V+ ++R ++ LY V
Sbjct: 911 S---QLSYSTSSSKRQSQQLEAL-QQQVKQLQNQLAECKKQHQEVISVYR-MHLLYAV 963
Score = 44.0 bits (99), Expect = 0.001
Identities = 75/350 (21%), Positives = 152/350 (43%), Gaps = 45/350 (12%)
Query: 65 YREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLE 124
Y+EA+EEI +L+ +K Q Q +A E+ + R+ +++N +
Sbjct: 610 YQEAQEEIMKLKDTLKSQMTQ---------EASDEAEDMKE-------AMNRMIDELNKQ 653
Query: 125 IQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHI 184
+ + ++E EL D K + A+ AEH E+L + N +R K
Sbjct: 654 VSELSQLYKEAQAEL---EDYRKRKSLEDVTAEYIHK-AEH--EKLMQLTNVSRAKAEDA 707
Query: 185 FRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQ 244
+ S Y LTQ +Q E + T H+ + +L+ K E +
Sbjct: 708 LSEMKSQYSKVLNELTQLKQLVDAQKE---NSVSITEHLQVITTLRTAAKEMEEKISNLK 764
Query: 245 MALLNQRI------SQLAENNISL------KSEIERLKASVIRTEESALANEKRLQEKMH 292
L ++ + QL E ++ +S E+L++S + +E S LA+ +L+E +
Sbjct: 765 EHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSS-LESEVSVLAS--KLKESVK 821
Query: 293 ECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKERE 352
E ++ E+ + R E S+ ++R E +T+ K + V EL ++ ++ +++ ++ E
Sbjct: 822 EKEKVHSEVVQIRSEVSQ-VKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKRYSE 880
Query: 353 ELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRRTASSTGDGDGENQE 402
+ K++ E ++ + L+ + SL + + ST ++Q+
Sbjct: 881 SSSKLEEDKDKKINEMSKE----VTKLKEALNSLSQLSYSTSSSKRQSQQ 926
Score = 32.7 bits (71), Expect = 2.4
Identities = 54/306 (17%), Positives = 122/306 (39%), Gaps = 22/306 (7%)
Query: 53 EQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDY--RVKYLQAQQLVEEQR-RQXXX 109
E V L Q Y+EA+ E+++ R K D +Y + ++ + QL R +
Sbjct: 649 ELNKQVSELSQLYKEAQAELEDYRK-RKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDA 707
Query: 110 XXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQ 169
++ S+ +N Q +L +K ++ L T +R + + I+
Sbjct: 708 LSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHL 767
Query: 170 LARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSL 229
++E+ A+ + + L T + + + QS + + V VL + L
Sbjct: 768 ASKEVEVAK-----LEKQLLEEKAAMTDAMVPRSSYEKLQSSL-----ESEVSVLA-SKL 816
Query: 230 KPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQE 289
K K E+ E + + +SQ+ K I+ L S + L ++ QE
Sbjct: 817 KESVKEKEKVHSE--VVQIRSEVSQVKRE----KENIQTLLKSKEQEVNELLQKFQQAQE 870
Query: 290 KMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEK 349
++ E + + ++ + + ++ +++ L ++++L ++S+ Q E
Sbjct: 871 ELAEMKRYSESSSKLEEDKDKKINEMSKEVTKLKEAL-NSLSQLSYSTSSSKRQSQQLEA 929
Query: 350 EREELK 355
++++K
Sbjct: 930 LQQQVK 935
>X75304-1|CAA53052.1| 3259|Homo sapiens giantin protein.
Length = 3259
Score = 48.0 bits (109), Expect = 6e-05
Identities = 75/379 (19%), Positives = 143/379 (37%), Gaps = 16/379 (4%)
Query: 21 RETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMK 80
RE Q KL EL+ + L G Q E+E + ++ E + I L T ++
Sbjct: 1388 RELQPKLDELQKLISKKEEDVSYLSG---QLSEKEAALTKIQTEIIEQEDLIKALHTQLE 1444
Query: 81 EQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELA 140
Q + D R+K LQ + +Q+ + +R +QI ++Q + +E L+E
Sbjct: 1445 MQAKE-HDERIKQLQVELCEMKQKPEEIGE---ESRAKQQIQRKLQAALISRKEALKENK 1500
Query: 141 PIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLT 200
+ + L + ++ ++ A E +E + ++ + L +L
Sbjct: 1501 SLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRSLL 1560
Query: 201 QEDLFGQSQSEIGRG----NKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLA 256
+ S + +D+ V SLK + EK L + L
Sbjct: 1561 ENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKEL-QKEYEILL 1619
Query: 257 ENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAH 316
++ ++ +E ER++ V E+ ++ L K+ E ++ EA + ++
Sbjct: 1620 QSYENVSNEAERIQHVV----EAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMK 1675
Query: 317 EQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQLRI 376
E+ K Q + ELE + RA+V A +E L + E E+ ++
Sbjct: 1676 EKMRKFAKSKQQKILELEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEELERVKMEY 1735
Query: 377 LGLQTQVQSLRRTASSTGD 395
L + QSL S +
Sbjct: 1736 ETLSKKFQSLMSEKDSLSE 1754
Score = 40.7 bits (91), Expect = 0.009
Identities = 81/388 (20%), Positives = 166/388 (42%), Gaps = 33/388 (8%)
Query: 20 HRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLM 79
+ +QN+L +LE + + L L S E+ EQ+ N+ + R+ +I +
Sbjct: 2300 YHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGI---IRQQEADIQNSKFSY 2356
Query: 80 KEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQEL 139
++ LQ R +L EE + + E I + I ++ + ++++EL
Sbjct: 2357 EQLETDLQASRE---LTSRLHEEINMKEQKIISLLSGKEEAIQVAIAELRQQHDKEIKEL 2413
Query: 140 APIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTL 199
+ + + L++ + +A+ + N QL L +++ + L S V +M+
Sbjct: 2414 ENLLSQEEEENIVLEE-ENKKAVDKTN--QLMETLKTIKKENIQQKAQLDS--FVKSMSS 2468
Query: 200 TQED---LFGQSQSEIGRG-----NKDQTVH--VLLHNSLKPPEKPPERGGDE--KQMAL 247
Q D + G Q R KDQ + +N LK + D+ + A
Sbjct: 2469 LQNDRDRIVGDYQQLEERHLSIILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAK 2528
Query: 248 LNQRISQLAEN---NISLKSEIERLKASVIRTEESALANE-KRLQEKMHECAQLGGELDR 303
L+ + Q E+ I++K ++ V + L N+ +L+EK+ E + +L R
Sbjct: 2529 LDAELIQYREDLNQVITIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKESEEANEDLRR 2588
Query: 304 TRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMK 363
+ ALQ + + L+ ++++L RQ+ A + + T +LK + ++
Sbjct: 2589 ----SFNALQEEKQDLSKEIESLKVSISQLTRQVTALQEE-GTLGLYHAQLKVK-EEEVH 2642
Query: 364 RLTENFEQAQLRILGLQTQVQSLRRTAS 391
RL+ F +Q RI L+ ++ +++ A+
Sbjct: 2643 RLSALFSSSQKRIAELEEELVCVQKEAA 2670
Score = 39.9 bits (89), Expect = 0.016
Identities = 70/376 (18%), Positives = 156/376 (41%), Gaps = 24/376 (6%)
Query: 23 TQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQ 82
TQ ++E E L ++ K+ +Q+ AL++ + A +I +L+ K +
Sbjct: 46 TQEDVQERLAYAEQLVVELKDIIRQKDVQLQQKDE--ALQEERKAADNKIKKLKLHAKAK 103
Query: 83 NDQLQDYRVKYLQAQQ-LVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAP 141
L Y ++ ++AQ V Q + + S + +EI+++K K QEK
Sbjct: 104 LTSLNKY-IEEMKAQGGTVLPTEPQSEEQLSKHDKSSTEEEMEIEKIKHKLQEK------ 156
Query: 142 IPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQ 201
+L+ Q +L A QA+ A+ + E E ++++ ++ +L + T +
Sbjct: 157 -EELISTLQAQLTQA-QAEQPAQSSTEM--EEFVMMKQQLQEKEEFISTLQAQLSQTQAE 212
Query: 202 EDLFGQSQSEIGRGNKDQTVHVLLHNS--LKPPEKPPERGGDEKQMALLNQRISQLAENN 259
+ +Q + + V LH L+ + ++++ +L +++ + E+
Sbjct: 213 Q----AAQQVVREKDARFETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEHEESL 268
Query: 260 ISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQT 319
+ ++ L+ + E+ ++LQ+ E L ++ R+E+ L++ +
Sbjct: 269 VGRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEHNTLRNTVETEREESKILLEKM--EL 326
Query: 320 ETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQLRILGL 379
E + L + L+ ++ Q A + + EL++R ++ E+ IL L
Sbjct: 327 EVAERKL--SFHNLQEEMHHLLEQFEQAGQAQAELESRYSALEQKHKAEMEEKTSHILSL 384
Query: 380 QTQVQSLRRTASSTGD 395
Q Q L+ + D
Sbjct: 385 QKTGQELQSACDALKD 400
Score = 31.9 bits (69), Expect = 4.3
Identities = 27/169 (15%), Positives = 74/169 (43%), Gaps = 4/169 (2%)
Query: 24 QNKLRELEMKFEGLATHT----NMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLM 79
QN+L +++++F +T + L + + E VR + E + + + +
Sbjct: 816 QNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEI 875
Query: 80 KEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQEL 139
+ + L + + QQ +EE+ +Q T Q+N E + ++ + ++L
Sbjct: 876 TKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEKFSLGVEIKTLKEQL 935
Query: 140 APIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYL 188
+ +A + ++++ + + + N ++++ ++E++ H F L
Sbjct: 936 NLLSRAEEAKKEQVEEDNEVSSGLKQNYDEMSPAGQISKEELQHEFDLL 984
>D25542-1|BAA05025.1| 3225|Homo sapiens golgi antigen gcp372 protein.
Length = 3225
Score = 48.0 bits (109), Expect = 6e-05
Identities = 75/379 (19%), Positives = 143/379 (37%), Gaps = 16/379 (4%)
Query: 21 RETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMK 80
RE Q KL EL+ + L G Q E+E + ++ E + I L T ++
Sbjct: 1354 RELQPKLDELQKLISKKEEDVSYLSG---QLSEKEAALTKIQTEIIEQEDLIKALHTQLE 1410
Query: 81 EQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELA 140
Q + D R+K LQ + +Q+ + +R +QI ++Q + +E L+E
Sbjct: 1411 MQAKE-HDERIKQLQVELCEMKQKPEEIGE---ESRAKQQIQRKLQAALISRKEALKENK 1466
Query: 141 PIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLT 200
+ + L + ++ ++ A E +E + ++ + L +L
Sbjct: 1467 SLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRSLL 1526
Query: 201 QEDLFGQSQSEIGRG----NKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLA 256
+ S + +D+ V SLK + EK L + L
Sbjct: 1527 ENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKEL-QKEYEILL 1585
Query: 257 ENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAH 316
++ ++ +E ER++ V E+ ++ L K+ E ++ EA + ++
Sbjct: 1586 QSYENVSNEAERIQHVV----EAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMK 1641
Query: 317 EQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQLRI 376
E+ K Q + ELE + RA+V A +E L + E E+ ++
Sbjct: 1642 EKMRKFAKSKQQKILELEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEELERVKMEY 1701
Query: 377 LGLQTQVQSLRRTASSTGD 395
L + QSL S +
Sbjct: 1702 ETLSKKFQSLMSEKDSLSE 1720
Score = 42.7 bits (96), Expect = 0.002
Identities = 73/378 (19%), Positives = 158/378 (41%), Gaps = 23/378 (6%)
Query: 23 TQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQ 82
TQ ++E E L ++ K+ +Q+ AL++ + A +I +L+ K +
Sbjct: 7 TQEDVQERLAYAEQLVVELKDIIRQKDVQLQQKDE--ALQEERKAADNKIKKLKLHAKAK 64
Query: 83 NDQLQDYRVKYLQAQQ-LVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAP 141
L Y ++ ++AQ V Q + + S + +EI+++K K QEK
Sbjct: 65 LTSLNKY-IEEMKAQGGTVLPTEPQSEEQLSKHDKSSTEEEMEIEKIKHKLQEK------ 117
Query: 142 IPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQ 201
+L+ Q +L A QA+ A+ + E E ++++ ++ +L + T +
Sbjct: 118 -EELISTLQAQLTQA-QAEQPAQSSTEM--EEFVMMKQQLQEKEEFISTLQAQLSQTQAE 173
Query: 202 EDLFGQSQSEIGRGNKDQ--TVHVLLHNS--LKPPEKPPERGGDEKQMALLNQRISQLAE 257
+ S ++ R KD V LH L+ + ++++ +L +++ + E
Sbjct: 174 QAAQLSSMQQVVR-EKDARFETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEHEE 232
Query: 258 NNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHE 317
+ + ++ L+ + E+ ++LQ+ E L ++ R+E+ L++
Sbjct: 233 SLVGRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEHNTLRNTVETEREESKILLEKM-- 290
Query: 318 QTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQLRIL 377
+ E + L + L+ ++ Q A + + EL++R ++ E+ IL
Sbjct: 291 ELEVAERKL--SFHNLQEEMHHLLEQFEQAGQAQAELESRYSALEQKHKAEMEEKTSHIL 348
Query: 378 GLQTQVQSLRRTASSTGD 395
LQ Q L+ + D
Sbjct: 349 SLQKTGQELQSACDALKD 366
Score = 40.7 bits (91), Expect = 0.009
Identities = 81/388 (20%), Positives = 166/388 (42%), Gaps = 33/388 (8%)
Query: 20 HRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLM 79
+ +QN+L +LE + + L L S E+ EQ+ N+ + R+ +I +
Sbjct: 2266 YHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGI---IRQQEADIQNSKFSY 2322
Query: 80 KEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQEL 139
++ LQ R +L EE + + E I + I ++ + ++++EL
Sbjct: 2323 EQLETDLQASRE---LTSRLHEEINMKEQKIISLLSGKEEAIQVAIAELRQQHDKEIKEL 2379
Query: 140 APIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTL 199
+ + + L++ + +A+ + N QL L +++ + L S V +M+
Sbjct: 2380 ENLLSQEEEENIVLEE-ENKKAVDKTN--QLMETLKTIKKENIQQKAQLDS--FVKSMSS 2434
Query: 200 TQED---LFGQSQSEIGRG-----NKDQTVH--VLLHNSLKPPEKPPERGGDE--KQMAL 247
Q D + G Q R KDQ + +N LK + D+ + A
Sbjct: 2435 LQNDRDRIVGDYQQLEERHLSIILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAK 2494
Query: 248 LNQRISQLAEN---NISLKSEIERLKASVIRTEESALANE-KRLQEKMHECAQLGGELDR 303
L+ + Q E+ I++K ++ V + L N+ +L+EK+ E + +L R
Sbjct: 2495 LDAELIQYREDLNQVITIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKESEEANEDLRR 2554
Query: 304 TRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMK 363
+ ALQ + + L+ ++++L RQ+ A + + T +LK + ++
Sbjct: 2555 ----SFNALQEEKQDLSKEIESLKVSISQLTRQVTALQEE-GTLGLYHAQLKVK-EEEVH 2608
Query: 364 RLTENFEQAQLRILGLQTQVQSLRRTAS 391
RL+ F +Q RI L+ ++ +++ A+
Sbjct: 2609 RLSALFSSSQKRIAELEEELVCVQKEAA 2636
Score = 31.9 bits (69), Expect = 4.3
Identities = 27/169 (15%), Positives = 74/169 (43%), Gaps = 4/169 (2%)
Query: 24 QNKLRELEMKFEGLATHT----NMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLM 79
QN+L +++++F +T + L + + E VR + E + + + +
Sbjct: 782 QNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEI 841
Query: 80 KEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQEL 139
+ + L + + QQ +EE+ +Q T Q+N E + ++ + ++L
Sbjct: 842 TKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEKFSLGVEIKTLKEQL 901
Query: 140 APIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYL 188
+ +A + ++++ + + + N ++++ ++E++ H F L
Sbjct: 902 NLLSRAEEAKKEQVEEDNEVSSGLKQNYDEMSPAGQISKEELQHEFDLL 950
>AF283527-1|AAG00497.1| 577|Homo sapiens FIP2 protein.
Length = 577
Score = 48.0 bits (109), Expect = 6e-05
Identities = 47/240 (19%), Positives = 106/240 (44%), Gaps = 11/240 (4%)
Query: 46 GSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRR 105
G+K +E+ V L C RE ++++ L +KE +++ D+ K + +E Q
Sbjct: 221 GAKNYFEHEELTVSQLLLCLREGNQKVERLEVALKEAKERVSDFEKKTSNRSE-IETQTE 279
Query: 106 QXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEH 165
+ E + E++ + L+ +EL L ++ K Q+ E
Sbjct: 280 GSTEKENDEEKGPETVGSEVEALNLQVTSLFKELQEAHTKLSEAELMKKRLQEKCQALER 339
Query: 166 NAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLL 225
+ ELN ++++V+ + L L + + ++ + + +++ E + Q H L
Sbjct: 340 KNSAIPSELN-EKQELVYPNKKL-ELQVESMLSEIKMEQ-AKTEDEKSKLTVLQMTHNKL 396
Query: 226 ----HNSLKPPEKPPERGGDEKQMALLNQRIS--QLAENNISLKS-EIERLKASVIRTEE 278
+N+LK E+ + ++ A+L + +LAE ++ K +++ +K ++ + EE
Sbjct: 397 LQEHNNALKTIEELTRKESEKVDRAVLKELSEKLELAEKALASKQLQMDEMKQTIAKQEE 456
>AF061034-2|AAC16047.1| 520|Homo sapiens FIP2 protein.
Length = 520
Score = 48.0 bits (109), Expect = 6e-05
Identities = 47/240 (19%), Positives = 106/240 (44%), Gaps = 11/240 (4%)
Query: 46 GSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRR 105
G+K +E+ V L C RE ++++ L +KE +++ D+ K + +E Q
Sbjct: 164 GAKNYFEHEELTVSQLLLCLREGNQKVERLEVALKEAKERVSDFEKKTSNRSE-IETQTE 222
Query: 106 QXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEH 165
+ E + E++ + L+ +EL L ++ K Q+ E
Sbjct: 223 GSTEKENDEEKGPETVGSEVEALNLQVTSLFKELQEAHTKLSEAELMKKRLQEKCQALER 282
Query: 166 NAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLL 225
+ ELN ++++V+ + L L + + ++ + + +++ E + Q H L
Sbjct: 283 KNSAIPSELN-EKQELVYPNKKL-ELQVESMLSEIKMEQ-AKTEDEKSKLTVLQMTHNKL 339
Query: 226 ----HNSLKPPEKPPERGGDEKQMALLNQRIS--QLAENNISLKS-EIERLKASVIRTEE 278
+N+LK E+ + ++ A+L + +LAE ++ K +++ +K ++ + EE
Sbjct: 340 LQEHNNALKTIEELTRKESEKVDRAVLKELSEKLELAEKALASKQLQMDEMKQTIAKQEE 399
>AF061034-1|AAC16046.1| 577|Homo sapiens FIP2 protein.
Length = 577
Score = 48.0 bits (109), Expect = 6e-05
Identities = 47/240 (19%), Positives = 106/240 (44%), Gaps = 11/240 (4%)
Query: 46 GSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRR 105
G+K +E+ V L C RE ++++ L +KE +++ D+ K + +E Q
Sbjct: 221 GAKNYFEHEELTVSQLLLCLREGNQKVERLEVALKEAKERVSDFEKKTSNRSE-IETQTE 279
Query: 106 QXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEH 165
+ E + E++ + L+ +EL L ++ K Q+ E
Sbjct: 280 GSTEKENDEEKGPETVGSEVEALNLQVTSLFKELQEAHTKLSEAELMKKRLQEKCQALER 339
Query: 166 NAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLL 225
+ ELN ++++V+ + L L + + ++ + + +++ E + Q H L
Sbjct: 340 KNSAIPSELN-EKQELVYPNKKL-ELQVESMLSEIKMEQ-AKTEDEKSKLTVLQMTHNKL 396
Query: 226 ----HNSLKPPEKPPERGGDEKQMALLNQRIS--QLAENNISLKS-EIERLKASVIRTEE 278
+N+LK E+ + ++ A+L + +LAE ++ K +++ +K ++ + EE
Sbjct: 397 LQEHNNALKTIEELTRKESEKVDRAVLKELSEKLELAEKALASKQLQMDEMKQTIAKQEE 456
>BC011621-1|AAH11621.1| 728|Homo sapiens hook homolog 1
(Drosophila) protein.
Length = 728
Score = 47.6 bits (108), Expect = 8e-05
Identities = 75/336 (22%), Positives = 138/336 (41%), Gaps = 36/336 (10%)
Query: 49 EQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXX 108
EQ E+ + A K YR EE+++ + +ND+L L EE R
Sbjct: 255 EQLQEENFRLEAAKDDYRVHCEELEKQLIEFQHRNDEL----------TSLAEETRALKD 304
Query: 109 XXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAE 168
S++ N V++ +++KLQ+L DL K ++K Q+ + HN
Sbjct: 305 EIDVLRA-TSDKANKLESTVEI-YRQKLQDL---NDLRK----QVKTLQETNMMYMHNTV 355
Query: 169 QLAREL---NCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLL 225
L EL N AR ++ R + L++ + + D + ++ LL
Sbjct: 356 SLEEELKKANAARTQLETYKRQVQDLHVKLSSESKRADTLAFEMKRL-----EEKHEALL 410
Query: 226 HNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEK 285
+ E+ +++ + L + + S E L A ++ E +
Sbjct: 411 KEKERLIEQRDTLKETNEELRCSQVQQDHLNQTDASATKSYENLAAEIMPVEYREVFIRL 470
Query: 286 RLQEKMHECAQLGGELDRTRDEASRALQRAH---EQTETVRKCLQTTVAELERQL----A 338
+ + KM Q G E +R +E L++ H + ET ++ + + EL++Q+
Sbjct: 471 QHENKMLRLQQEGSENERI-EELQEQLEQKHRKMNELETEQRLSKERIRELQQQIEDLQK 529
Query: 339 ASRAQVSTAEKE-REELKNRLHWQMKRLTENFEQAQ 373
+ + Q S +E E +LK +L M++LTE E+ Q
Sbjct: 530 SLQEQGSKSEGESSSKLKQKLEAHMEKLTEVHEELQ 565
>AL121586-4|CAB89415.1| 2442|Homo sapiens centrosomal protein 250kDa
protein.
Length = 2442
Score = 47.6 bits (108), Expect = 8e-05
Identities = 79/388 (20%), Positives = 156/388 (40%), Gaps = 13/388 (3%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYR--EAREE-IDEL 75
Q +++L ELE K + + + + K+Q E L++ + E +++ I EL
Sbjct: 1520 QRNVLEHQLLELEKKDQMIESQRGQVQDLKKQLVTLECLALELEENHHKMECQQKLIKEL 1579
Query: 76 RTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEK 135
+ Q L + + Q ++ Q Q +T ++ ++ Q VK + +E+
Sbjct: 1580 EGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQ-REQ 1638
Query: 136 LQELAPIPD-LLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLV 194
++EL + L + + R ++ + + +Q R+ E + I L
Sbjct: 1639 IEELQRQKEHLTQDLERRDQELMLQKERIQVLEDQRTRQTKILEEDLEQIKLSLRERGRE 1698
Query: 195 TTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQ 254
T TQ L Q ++E G+G L H L +K E ++ + L + Q
Sbjct: 1699 LT---TQRQLM-QERAEEGKGPSKAQRGSLEHMKLILRDKEKEVECQQEHIHELQELKDQ 1754
Query: 255 LAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQR 314
L + L ++ + + E+ + +++LQE + L DEA RAL +
Sbjct: 1755 LEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQ 1814
Query: 315 AHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQL 374
++ E +++ Q + ER + A E+ LK R H +++ E + +
Sbjct: 1815 RDQELEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKER-HGELQDHKEQARRLEE 1873
Query: 375 RILGLQTQVQSLRRTASSTGDGDGENQE 402
+ +VQ+L GD E++E
Sbjct: 1874 ELAVEGRRVQALEEV---LGDLRAESRE 1898
Score = 37.1 bits (82), Expect = 0.11
Identities = 88/401 (21%), Positives = 161/401 (40%), Gaps = 42/401 (10%)
Query: 22 ETQNKLRELEMKFEGLATHTNM--LMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLM 79
+TQ +L + + E L + L + Q A ++ AR+ D+L L
Sbjct: 936 QTQKELADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAARQHRDDLAALQ 995
Query: 80 KEQNDQLQD-----YRVKYLQ--------AQQLVEEQRRQXXXXXXXNTRISEQINLEIQ 126
+E + LQD +V+ L+ +Q+LVE++ ++ RI +++ E
Sbjct: 996 EESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKELEREKA 1055
Query: 127 RVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFR 186
+ L EK Q L + + Q L +Q A+ ++L+ ++ R++V +
Sbjct: 1056 SLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQMELLRQEV----K 1111
Query: 187 YLYSLYLVTTMTLTQEDLFGQSQSEIGRGN--KDQTVHVLLHNSLKPPEKPPERGGDEKQ 244
+ +L L +E + R + + L L+ E E E+Q
Sbjct: 1112 EKEADFLAQEAQLLEELEASHITEQQLRASLWAQEAKAAQLQLRLRSTESQLEALAAEQQ 1171
Query: 245 MALLNQRISQLAENNISLKSEIERLKASVI--RTEESALANEK----RLQEKMHECAQL- 297
Q +QLA SL S +++ SV R E S + L+ + L
Sbjct: 1172 PGNQAQAQAQLA----SLYSALQQALGSVCESRPELSGGGDSAPSVWGLEPDQNGARSLF 1227
Query: 298 --GGELDRTRDEA-SRALQRAHE---QTETVRKCLQTTVAELERQLAASRAQVSTAEKER 351
G L EA + AL + H+ +T+ R L+ V +LE +L + A+ S E
Sbjct: 1228 KRGPLLTALSAEAVASALHKLHQDLWKTQQTRDVLRDQVQKLEERLTDTEAEKSQVHTEL 1287
Query: 352 EELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRRTASS 392
++L+ +L Q + +E Q L++++ L T +S
Sbjct: 1288 QDLQRQLS-QNQEEKSKWEGKQ---NSLESELMELHETMAS 1324
Score = 36.3 bits (80), Expect = 0.20
Identities = 32/142 (22%), Positives = 62/142 (43%), Gaps = 4/142 (2%)
Query: 248 LNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDE 307
LNQ++ QL E N S+ S +E + + + EKR + + L +L + +E
Sbjct: 615 LNQQLLQLEEENQSVCSRMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKA-EE 673
Query: 308 ASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKE---REELKNRLHWQMKR 364
A LQ + ++ +Q ++E Q A+ Q+ +E +EE+ R + +
Sbjct: 674 AGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEA 733
Query: 365 LTENFEQAQLRILGLQTQVQSL 386
L ++R+ ++ Q L
Sbjct: 734 LVREKAALEVRLQAVERDRQDL 755
Score = 35.1 bits (77), Expect = 0.46
Identities = 88/400 (22%), Positives = 163/400 (40%), Gaps = 38/400 (9%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEID-ELRT 77
+ E Q KL E + E T L +E ++EV RA+++ RE+ E+R
Sbjct: 688 EKEEIQKKLSESRHQQEAATTQLEQL--HQEAKRQEEVLARAVQEKEALVREKAALEVRL 745
Query: 78 LMKEQNDQ-LQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRV---KLKFQ 133
E++ Q L + A++L+E + Q+ ++IQ V K Q
Sbjct: 746 QAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNSVIEVTKGQLEVQIQTVTQAKEVIQ 805
Query: 134 EKLQELAPIPDLLKATQMRLKDAQQAQ-AIAEHNAEQLARELNCAREKVVHIFRYLYSL- 191
+++ L D ++ + +DA Q A AE + + A EK V+ R +
Sbjct: 806 GEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLREKWEKE 865
Query: 192 --YLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGG-------DE 242
+ + E L + + E+ K+Q + + + E+ E
Sbjct: 866 RSWHQQELAKALESL-EREKMELEMRLKEQQTEMEAIQAQREEERTQAESALCQMQLETE 924
Query: 243 KQMALLNQRISQLAENNISLKSEIERL----KASVIRTEESALANEKRLQEKMHECAQLG 298
K+ L + + Q + ++ERL K ++ +E+ + +LQE E +
Sbjct: 925 KERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAA 984
Query: 299 GELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKE-REELK-- 355
+ RD+ + ALQ + LQ V +L+ QL A E+E +E+L+
Sbjct: 985 RQ---HRDDLA-ALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRET 1040
Query: 356 ---NRLHWQMKR----LTENFEQAQLRILGLQTQVQSLRR 388
NR+ +++R LT + + + R+L LQ + S+R+
Sbjct: 1041 QEYNRIQKELEREKASLTLSLMEKEQRLLVLQ-EADSIRQ 1079
Score = 35.1 bits (77), Expect = 0.46
Identities = 60/302 (19%), Positives = 120/302 (39%), Gaps = 22/302 (7%)
Query: 49 EQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXX 108
EQA E EV RAL+ + +A + ++KE++ +L+ R + ++ E R +
Sbjct: 1912 EQAQEHEVETRALQDSWLQA-------QAVLKERDQELEALRAESQSSRHQEEAARAR-- 1962
Query: 109 XXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAE 168
+E + + + Q K Q L +L ++ + Q + + ++
Sbjct: 1963 ---------AEALQEALGKAHAALQGKEQHLLEQAELSRSLEASTATLQASLDACQAHSR 2013
Query: 169 QLARELNCAREKVV-HIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHN 227
QL L ++ RY + + L Q D + Q E + + + N
Sbjct: 2014 QLEEALRIQEGEIQDQDLRYQEDVQQL-QQALAQRDEELRHQQEREQLLEKSLAQRVQEN 2072
Query: 228 SLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRL 287
++ + + +E+++ L+Q + +L + EI L+ + R AL + +
Sbjct: 2073 MIQEKQNLGQE-REEEEIRGLHQSVRELQLTLAQKEQEILELRETQQRNNLEALPHSHKT 2131
Query: 288 QEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTA 347
+ +L R + E R LQ A QTE + +L LA ++A VS+
Sbjct: 2132 SPMEEQSLKLDSLEPRLQRELER-LQAALRQTEAREIEWREKAQDLALSLAQTKASVSSL 2190
Query: 348 EK 349
++
Sbjct: 2191 QE 2192
Score = 33.5 bits (73), Expect = 1.4
Identities = 85/386 (22%), Positives = 150/386 (38%), Gaps = 24/386 (6%)
Query: 17 RCQHRETQNKLRE------LEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREA-R 69
R +E Q KLRE ++ + E + + KEQ +++Q A R
Sbjct: 1027 RLVEQEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALR 1086
Query: 70 EEIDELRTLMKEQNDQLQDYR--VKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQR 127
+++ E + KE + Q++ R VK +A L +E + T + +L Q
Sbjct: 1087 QDMQEAQGEQKELSAQMELLRQEVKEKEADFLAQEAQLLEELEASHITEQQLRASLWAQE 1146
Query: 128 VKL-KFQEKLQELAPIPDLLKATQMRLKDAQ-QAQAIAEHNAEQLARELNC-AREKVVHI 184
K + Q +L+ + L A Q AQ QAQ + ++A Q A C +R ++
Sbjct: 1147 AKAAQLQLRLRSTESQLEALAAEQQPGNQAQAQAQLASLYSALQQALGSVCESRPELSGG 1206
Query: 185 FRYLYSLYLVTTMTLTQEDLF--GQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDE 242
S++ + LF G + + +H L H L ++ + D+
Sbjct: 1207 GDSAPSVWGLEPDQNGARSLFKRGPLLTALSAEAVASALHKL-HQDLWKTQQTRDVLRDQ 1265
Query: 243 KQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELD 302
Q L +R++ + +E++ L+ + + +E E + E +L +
Sbjct: 1266 VQK--LEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELMELHETMA 1323
Query: 303 RTRDEASRA-LQRAHEQTE-----TVRKCLQTTVAELERQLAASRAQVSTAEKEREELKN 356
+ RA LQR Q E ++ L V L+ + +RAQ S A E+L+
Sbjct: 1324 SLQSRLRRAELQRMEAQGERELLQAAKENLTAQVEHLQAAVVEARAQASAAGILEEDLRT 1383
Query: 357 RLHWQMKRLTENFEQAQLRILGLQTQ 382
+K E E + R LQ Q
Sbjct: 1384 -ARSALKLKNEEVESERERAQALQEQ 1408
Score = 31.9 bits (69), Expect = 4.3
Identities = 35/144 (24%), Positives = 62/144 (43%), Gaps = 11/144 (7%)
Query: 250 QRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGE---LDRTRD 306
Q + L + + + L+ + EE A +RLQ+ E L G+ L D
Sbjct: 400 QAVQDLRQQLAGCQEAVNLLQQQHDQWEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVD 459
Query: 307 EASRA---LQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMK 363
S+ LQ+A E+ + L+ L R + Q +A+ ++EE + LH ++
Sbjct: 460 SLSKERELLQKAREELRQQLEVLEQEAWRLRRVNVELQLQGDSAQGQKEEQQEELHLAVR 519
Query: 364 RLTENFEQAQLRILGLQT-QVQSL 386
E+ Q ++GL+ Q +SL
Sbjct: 520 ER----ERLQEMLMGLEAKQSESL 539
>AL035416-6|CAI22779.1| 728|Homo sapiens hook homolog 1
(Drosophila) protein.
Length = 728
Score = 47.6 bits (108), Expect = 8e-05
Identities = 75/336 (22%), Positives = 138/336 (41%), Gaps = 36/336 (10%)
Query: 49 EQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXX 108
EQ E+ + A K YR EE+++ + +ND+L L EE R
Sbjct: 255 EQLQEENFRLEAAKDDYRVHCEELEKQLIEFQHRNDEL----------TSLAEETRALKD 304
Query: 109 XXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAE 168
S++ N V++ +++KLQ+L DL K ++K Q+ + HN
Sbjct: 305 EIDVLRA-TSDKANKLESTVEI-YRQKLQDL---NDLRK----QVKTLQETNMMYMHNTV 355
Query: 169 QLAREL---NCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLL 225
L EL N AR ++ R + L++ + + D + ++ LL
Sbjct: 356 SLEEELKKANAARTQLETYKRQVQDLHVKLSSESKRADTLAFEMKRL-----EEKHEALL 410
Query: 226 HNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEK 285
+ E+ +++ + L + + S E L A ++ E +
Sbjct: 411 KEKERLIEQRDTLKETNEELRCSQVQQDHLNQTDASATKSYENLAAEIMPVEYREVFIRL 470
Query: 286 RLQEKMHECAQLGGELDRTRDEASRALQRAH---EQTETVRKCLQTTVAELERQL----A 338
+ + KM Q G E +R +E L++ H + ET ++ + + EL++Q+
Sbjct: 471 QHENKMLRLQQEGSENERI-EELQEQLEQKHRKMNELETEQRLSKERIRELQQQIEDLQK 529
Query: 339 ASRAQVSTAEKE-REELKNRLHWQMKRLTENFEQAQ 373
+ + Q S +E E +LK +L M++LTE E+ Q
Sbjct: 530 SLQEQGSKSEGESSSKLKQKLEAHMEKLTEVHEELQ 565
>AJ131693-1|CAB40713.1| 3908|Homo sapiens AKAP450 protein protein.
Length = 3908
Score = 47.6 bits (108), Expect = 8e-05
Identities = 81/372 (21%), Positives = 162/372 (43%), Gaps = 29/372 (7%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGS-KEQAFEQEVNVR-ALKQCYREAREEIDELR 76
Q E + L + + K E + L K EQ+ V + K+ +E I+EL
Sbjct: 276 QLEEQDHLLEDYQKKKEDFTMQISFLQEKIKVYEMEQDKKVENSNKEEIQEKETIIEELN 335
Query: 77 TLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKL 136
T + E+ + + + K A +L+ E + Q N I + + LE+ K K ++
Sbjct: 336 TKIIEEEKKTLELKDKLTTADKLLGELQEQIVQK---NQEI-KNMKLELTNSKQKERQSS 391
Query: 137 QELAPIPDLLKATQMRL-KDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVT 195
+E+ + ++ Q R KD+Q I + ++ R+L R ++ +Y +V
Sbjct: 392 EEIKQLMGTVEELQKRNHKDSQFETDIVQRMEQETQRKLEQLRAELDE----MYGQQIVQ 447
Query: 196 TMTLTQEDLFGQSQSEIGRGNKDQTVHV-LLHNSLKPPEKPPERGGDEKQMALLNQRISQ 254
+++L Q +++ + +T H + N+L+ +E Q+ L+N I++
Sbjct: 448 M----KQELIRQHMAQM---EEMKTRHKGEMENALRSYSNITV---NEDQIKLMNVAINE 497
Query: 255 LAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRD---EASRA 311
L S+ E+LK + E A +++L++ + E + ++ R R E
Sbjct: 498 LNIKLQDTNSQKEKLKEELGLILEEKCALQRQLEDLVEELSFSREQIQRARQTIAEQESK 557
Query: 312 LQRAHEQTETVR--KCLQTTVAELERQLAAS-RAQVSTAEKEREELKNRLHWQMKRLTEN 368
L AH+ TV K + +E ++L A+V+ + + E L+ + + R+ E+
Sbjct: 558 LNEAHKSLSTVEDLKAEIVSASESRKELELKHEAEVTNYKIKLEMLEKEKNAVLDRMAES 617
Query: 369 FEQAQLRILGLQ 380
++A+L L Q
Sbjct: 618 -QEAELERLRTQ 628
Score = 43.6 bits (98), Expect = 0.001
Identities = 78/382 (20%), Positives = 147/382 (38%), Gaps = 24/382 (6%)
Query: 17 RCQHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELR 76
R Q E +NKL + +M+ GLA + M +++Q V Q +E EID+L
Sbjct: 2244 RLQELEQENKLFKDDMEKLGLAIKESDAMSTQDQ----HVLFGKFAQIIQEKEVEIDQLN 2299
Query: 77 TLMKEQNDQLQ---DYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQ 133
+ + QL+ D +V + +L+ + Q + EI+++ +
Sbjct: 2300 EQVTKLQQQLKITTDNKV-IEEKNELIRDLETQIECLMSDQECVKRNREEEIEQLNEVIE 2358
Query: 134 EKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYL 193
+ QELA I + T M + +H + + E ++V + +
Sbjct: 2359 KLQQELANIG---QKTSMNAHSLSEEADSLKHQLDVVIAEKLALEQQVETANEEMTFMKN 2415
Query: 194 VTTMTLTQEDLFGQSQSEIGRGNKD-QTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRI 252
V T + + Q + R + + + + NS+ + E ++ L +
Sbjct: 2416 VLKETNFKMNQLTQELFSLKRERESVEKIQSIPENSVNVAIDHLSKDKPELEVVLTEDAL 2475
Query: 253 SQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRAL 312
L EN KS E K S+I E L E + K E Q ++ +++
Sbjct: 2476 KSL-ENQTYFKSFEENGKGSIINLETRLLQLESTVSAKDLELTQCYKQIKDMQEQGQFET 2534
Query: 313 QRAHEQTETVRKCLQTTVAEL---ERQLAASRA--------QVSTAEKEREELKNRLHWQ 361
+ ++ ++K ++ VA + QL A + Q ++E ER ++N +
Sbjct: 2535 EMLQKKIVNLQKIVEEKVAAALVSQIQLEAVQEYAKFCQDNQTISSEPERTNIQNLNQLR 2594
Query: 362 MKRLTENFEQAQLRILGLQTQV 383
L + LRI L++QV
Sbjct: 2595 EDELGSDISALTLRISELESQV 2616
>AJ010770-1|CAA09361.1| 3911|Homo sapiens Hyperion protein protein.
Length = 3911
Score = 47.6 bits (108), Expect = 8e-05
Identities = 81/372 (21%), Positives = 162/372 (43%), Gaps = 29/372 (7%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGS-KEQAFEQEVNVR-ALKQCYREAREEIDELR 76
Q E + L + + K E + L K EQ+ V + K+ +E I+EL
Sbjct: 288 QLEEQDHLLEDYQKKKEDFTMQISFLQEKIKVYEMEQDKKVENSNKEEIQEKETIIEELN 347
Query: 77 TLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKL 136
T + E+ + + + K A +L+ E + Q N I + + LE+ K K ++
Sbjct: 348 TKIIEEEKKTLELKDKLTTADKLLGELQEQIVQK---NQEI-KNMKLELTNSKQKERQSS 403
Query: 137 QELAPIPDLLKATQMRL-KDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVT 195
+E+ + ++ Q R KD+Q I + ++ R+L R ++ +Y +V
Sbjct: 404 EEIKQLMGTVEELQKRNHKDSQFETDIVQRMEQETQRKLEQLRAELDE----MYGQQIVQ 459
Query: 196 TMTLTQEDLFGQSQSEIGRGNKDQTVHV-LLHNSLKPPEKPPERGGDEKQMALLNQRISQ 254
+++L Q +++ + +T H + N+L+ +E Q+ L+N I++
Sbjct: 460 M----KQELIRQHMAQM---EEMKTRHKGEMENALRSYSNITV---NEDQIKLMNVAINE 509
Query: 255 LAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRD---EASRA 311
L S+ E+LK + E A +++L++ + E + ++ R R E
Sbjct: 510 LNIKLQDTNSQKEKLKEELGLILEEKCALQRQLEDLVEELSFSREQIQRARQTIAEQESK 569
Query: 312 LQRAHEQTETVR--KCLQTTVAELERQLAAS-RAQVSTAEKEREELKNRLHWQMKRLTEN 368
L AH+ TV K + +E ++L A+V+ + + E L+ + + R+ E+
Sbjct: 570 LNEAHKSLSTVEDLKAEIVSASESRKELELKHEAEVTNYKIKLEMLEKEKNAVLDRMAES 629
Query: 369 FEQAQLRILGLQ 380
++A+L L Q
Sbjct: 630 -QEAELERLRTQ 640
Score = 43.6 bits (98), Expect = 0.001
Identities = 78/382 (20%), Positives = 147/382 (38%), Gaps = 24/382 (6%)
Query: 17 RCQHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELR 76
R Q E +NKL + +M+ GLA + M +++Q V Q +E EID+L
Sbjct: 2255 RLQELEQENKLFKDDMEKLGLAIKESDAMSTQDQ----HVLFGKFAQIIQEKEVEIDQLN 2310
Query: 77 TLMKEQNDQLQ---DYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQ 133
+ + QL+ D +V + +L+ + Q + EI+++ +
Sbjct: 2311 EQVTKLQQQLKITTDNKV-IEEKNELIRDLETQIECLMSDQECVKRNREEEIEQLNEVIE 2369
Query: 134 EKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYL 193
+ QELA I + T M + +H + + E ++V + +
Sbjct: 2370 KLQQELANIG---QKTSMNAHSLSEEADSLKHQLDVVIAEKLALEQQVETANEEMTFMKN 2426
Query: 194 VTTMTLTQEDLFGQSQSEIGRGNKD-QTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRI 252
V T + + Q + R + + + + NS+ + E ++ L +
Sbjct: 2427 VLKETNFKMNQLTQELFSLKRERESVEKIQSIPENSVNVAIDHLSKDKPELEVVLTEDAL 2486
Query: 253 SQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRAL 312
L EN KS E K S+I E L E + K E Q ++ +++
Sbjct: 2487 KSL-ENQTYFKSFEENGKGSIINLETRLLQLESTVSAKDLELTQCYKQIKDMQEQGQFET 2545
Query: 313 QRAHEQTETVRKCLQTTVAEL---ERQLAASRA--------QVSTAEKEREELKNRLHWQ 361
+ ++ ++K ++ VA + QL A + Q ++E ER ++N +
Sbjct: 2546 EMLQKKIVNLQKIVEEKVAAALVSQIQLEAVQEYAKFCQDNQTISSEPERTNIQNLNQLR 2605
Query: 362 MKRLTENFEQAQLRILGLQTQV 383
L + LRI L++QV
Sbjct: 2606 EDELGSDISALTLRISELESQV 2627
>AF049105-1|AAC07988.1| 2442|Homo sapiens centrosomal Nek2-associated
protein 1 protein.
Length = 2442
Score = 47.6 bits (108), Expect = 8e-05
Identities = 79/388 (20%), Positives = 156/388 (40%), Gaps = 13/388 (3%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYR--EAREE-IDEL 75
Q +++L ELE K + + + + K+Q E L++ + E +++ I EL
Sbjct: 1520 QRNVLEHQLLELEKKDQMIESQRGQVQDLKKQLVTLECLALELEENHHKMECQQKLIKEL 1579
Query: 76 RTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEK 135
+ Q L + + Q ++ Q Q +T ++ ++ Q VK + +E+
Sbjct: 1580 EGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQ-REQ 1638
Query: 136 LQELAPIPD-LLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLV 194
++EL + L + + R ++ + + +Q R+ E + I L
Sbjct: 1639 IEELQRQKEHLTQDLERRDQELMLQKERIQVLEDQRTRQTKILEEDLEQIKLSLRERGRE 1698
Query: 195 TTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQ 254
T TQ L Q ++E G+G L H L +K E ++ + L + Q
Sbjct: 1699 LT---TQRQLM-QERAEEGKGPSKAQRGSLEHMKLILRDKEKEVECQQEHIHELQELKDQ 1754
Query: 255 LAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQR 314
L + L ++ + + E+ + +++LQE + L DEA RAL +
Sbjct: 1755 LEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQ 1814
Query: 315 AHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQL 374
++ E +++ Q + ER + A E+ LK R H +++ E + +
Sbjct: 1815 RDQELEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKER-HGELQDHKEQARRLEE 1873
Query: 375 RILGLQTQVQSLRRTASSTGDGDGENQE 402
+ +VQ+L GD E++E
Sbjct: 1874 ELAVEGRRVQALEEV---LGDLRAESRE 1898
Score = 37.1 bits (82), Expect = 0.11
Identities = 88/401 (21%), Positives = 161/401 (40%), Gaps = 42/401 (10%)
Query: 22 ETQNKLRELEMKFEGLATHTNM--LMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLM 79
+TQ +L + + E L + L + Q A ++ AR+ D+L L
Sbjct: 936 QTQKELADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAARQHRDDLAALQ 995
Query: 80 KEQNDQLQD-----YRVKYLQ--------AQQLVEEQRRQXXXXXXXNTRISEQINLEIQ 126
+E + LQD +V+ L+ +Q+LVE++ ++ RI +++ E
Sbjct: 996 EESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKELEREKA 1055
Query: 127 RVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFR 186
+ L EK Q L + + Q L +Q A+ ++L+ ++ R++V +
Sbjct: 1056 SLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQMELLRQEV----K 1111
Query: 187 YLYSLYLVTTMTLTQEDLFGQSQSEIGRGN--KDQTVHVLLHNSLKPPEKPPERGGDEKQ 244
+ +L L +E + R + + L L+ E E E+Q
Sbjct: 1112 EKEADFLAQEAQLLEELEASHITEQQLRASLWAQEAKAAQLQLRLRSTESQLEALAAEQQ 1171
Query: 245 MALLNQRISQLAENNISLKSEIERLKASVI--RTEESALANEK----RLQEKMHECAQL- 297
Q +QLA SL S +++ SV R E S + L+ + L
Sbjct: 1172 PGNQAQAQAQLA----SLYSALQQALGSVCESRPELSGGGDSAPSVWGLEPDQNGARSLF 1227
Query: 298 --GGELDRTRDEA-SRALQRAHE---QTETVRKCLQTTVAELERQLAASRAQVSTAEKER 351
G L EA + AL + H+ +T+ R L+ V +LE +L + A+ S E
Sbjct: 1228 KRGPLLTALSAEAVASALHKLHQDLWKTQQTRDVLRDQVQKLEERLTDTEAEKSQVHTEL 1287
Query: 352 EELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRRTASS 392
++L+ +L Q + +E Q L++++ L T +S
Sbjct: 1288 QDLQRQLS-QNQEEKSKWEGKQ---NSLESELMELHETMAS 1324
Score = 36.3 bits (80), Expect = 0.20
Identities = 32/142 (22%), Positives = 62/142 (43%), Gaps = 4/142 (2%)
Query: 248 LNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDE 307
LNQ++ QL E N S+ S +E + + + EKR + + L +L + +E
Sbjct: 615 LNQQLLQLEEENQSVCSRMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKA-EE 673
Query: 308 ASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKE---REELKNRLHWQMKR 364
A LQ + ++ +Q ++E Q A+ Q+ +E +EE+ R + +
Sbjct: 674 AGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEA 733
Query: 365 LTENFEQAQLRILGLQTQVQSL 386
L ++R+ ++ Q L
Sbjct: 734 LVREKAALEVRLQAVERDRQDL 755
Score = 35.1 bits (77), Expect = 0.46
Identities = 88/400 (22%), Positives = 163/400 (40%), Gaps = 38/400 (9%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEID-ELRT 77
+ E Q KL E + E T L +E ++EV RA+++ RE+ E+R
Sbjct: 688 EKEEIQKKLSESRHQQEAATTQLEQL--HQEAKRQEEVLARAVQEKEALVREKAALEVRL 745
Query: 78 LMKEQNDQ-LQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRV---KLKFQ 133
E++ Q L + A++L+E + Q+ ++IQ V K Q
Sbjct: 746 QAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNSVIEVTKGQLEVQIQTVTQAKEVIQ 805
Query: 134 EKLQELAPIPDLLKATQMRLKDAQQAQ-AIAEHNAEQLARELNCAREKVVHIFRYLYSL- 191
+++ L D ++ + +DA Q A AE + + A EK V+ R +
Sbjct: 806 GEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLREKWEKE 865
Query: 192 --YLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGG-------DE 242
+ + E L + + E+ K+Q + + + E+ E
Sbjct: 866 RSWHQQELAKALESL-EREKMELEMRLKEQQTEMEAIQAQREEERTQAESALCQMQLETE 924
Query: 243 KQMALLNQRISQLAENNISLKSEIERL----KASVIRTEESALANEKRLQEKMHECAQLG 298
K+ L + + Q + ++ERL K ++ +E+ + +LQE E +
Sbjct: 925 KERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAA 984
Query: 299 GELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKE-REELK-- 355
+ RD+ + ALQ + LQ V +L+ QL A E+E +E+L+
Sbjct: 985 RQ---HRDDLA-ALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRET 1040
Query: 356 ---NRLHWQMKR----LTENFEQAQLRILGLQTQVQSLRR 388
NR+ +++R LT + + + R+L LQ + S+R+
Sbjct: 1041 QEYNRIQKELEREKASLTLSLMEKEQRLLVLQ-EADSIRQ 1079
Score = 35.1 bits (77), Expect = 0.46
Identities = 60/302 (19%), Positives = 120/302 (39%), Gaps = 22/302 (7%)
Query: 49 EQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXX 108
EQA E EV RAL+ + +A + ++KE++ +L+ R + ++ E R +
Sbjct: 1912 EQAQEHEVETRALQDSWLQA-------QAVLKERDQELEALRAESQSSRHQEEAARAR-- 1962
Query: 109 XXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAE 168
+E + + + Q K Q L +L ++ + Q + + ++
Sbjct: 1963 ---------AEALQEALGKAHAALQGKEQHLLEQAELSRSLEASTATLQASLDACQAHSR 2013
Query: 169 QLARELNCAREKVV-HIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHN 227
QL L ++ RY + + L Q D + Q E + + + N
Sbjct: 2014 QLEEALRIQEGEIQDQDLRYQEDVQQL-QQALAQRDEELRHQQEREQLLEKSLAQRVQEN 2072
Query: 228 SLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRL 287
++ + + +E+++ L+Q + +L + EI L+ + R AL + +
Sbjct: 2073 MIQEKQNLGQE-REEEEIRGLHQSVRELQLTLAQKEQEILELRETQQRNNLEALPHSHKT 2131
Query: 288 QEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTA 347
+ +L R + E R LQ A QTE + +L LA ++A VS+
Sbjct: 2132 SPMEEQSLKLDSLEPRLQRELER-LQAALRQTEAREIEWREKAQDLALSLAQTKASVSSL 2190
Query: 348 EK 349
++
Sbjct: 2191 QE 2192
Score = 33.5 bits (73), Expect = 1.4
Identities = 85/386 (22%), Positives = 150/386 (38%), Gaps = 24/386 (6%)
Query: 17 RCQHRETQNKLRE------LEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREA-R 69
R +E Q KLRE ++ + E + + KEQ +++Q A R
Sbjct: 1027 RLVEQEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALR 1086
Query: 70 EEIDELRTLMKEQNDQLQDYR--VKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQR 127
+++ E + KE + Q++ R VK +A L +E + T + +L Q
Sbjct: 1087 QDMQEAQGEQKELSAQMELLRQEVKEKEADFLAQEAQLLEELEASHITEQQLRASLWAQE 1146
Query: 128 VKL-KFQEKLQELAPIPDLLKATQMRLKDAQ-QAQAIAEHNAEQLARELNC-AREKVVHI 184
K + Q +L+ + L A Q AQ QAQ + ++A Q A C +R ++
Sbjct: 1147 AKAAQLQLRLRSTESQLEALAAEQQPGNQAQAQAQLASLYSALQQALGSVCESRPELSGG 1206
Query: 185 FRYLYSLYLVTTMTLTQEDLF--GQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDE 242
S++ + LF G + + +H L H L ++ + D+
Sbjct: 1207 GDSAPSVWGLEPDQNGARSLFKRGPLLTALSAEAVASALHKL-HQDLWKTQQTRDVLRDQ 1265
Query: 243 KQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELD 302
Q L +R++ + +E++ L+ + + +E E + E +L +
Sbjct: 1266 VQK--LEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELMELHETMA 1323
Query: 303 RTRDEASRA-LQRAHEQTE-----TVRKCLQTTVAELERQLAASRAQVSTAEKEREELKN 356
+ RA LQR Q E ++ L V L+ + +RAQ S A E+L+
Sbjct: 1324 SLQSRLRRAELQRMEAQGERELLQAAKENLTAQVEHLQAAVVEARAQASAAGILEEDLRT 1383
Query: 357 RLHWQMKRLTENFEQAQLRILGLQTQ 382
+K E E + R LQ Q
Sbjct: 1384 -ARSALKLKNEEVESERERAQALQEQ 1408
>AF044923-1|AAC09298.1| 728|Homo sapiens hook1 protein protein.
Length = 728
Score = 47.6 bits (108), Expect = 8e-05
Identities = 75/336 (22%), Positives = 138/336 (41%), Gaps = 36/336 (10%)
Query: 49 EQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXX 108
EQ E+ + A K YR EE+++ + +ND+L L EE R
Sbjct: 255 EQLQEENFRLEAAKDDYRVHCEELEKQLIEFQHRNDEL----------TSLAEETRALKD 304
Query: 109 XXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAE 168
S++ N V++ +++KLQ+L DL K ++K Q+ + HN
Sbjct: 305 EIDVLRA-TSDKANKLESTVEI-YRQKLQDL---NDLRK----QVKTLQETNMMYMHNTV 355
Query: 169 QLAREL---NCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLL 225
L EL N AR ++ R + L++ + + D + ++ LL
Sbjct: 356 SLEEELKKANAARTQLETYKRQVQDLHVKLSSESKRADTLAFEMKRL-----EEKHEALL 410
Query: 226 HNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEK 285
+ E+ +++ + L + + S E L A ++ E +
Sbjct: 411 KEKERLIEQRDTLKETNEELRCSQVQQDHLNQTDASATKSYENLAAEIMPVEYREVFIRL 470
Query: 286 RLQEKMHECAQLGGELDRTRDEASRALQRAH---EQTETVRKCLQTTVAELERQL----A 338
+ + KM Q G E +R +E L++ H + ET ++ + + EL++Q+
Sbjct: 471 QHENKMLRLQQEGSENERI-EELQEQLEQKHRKMNELETEQRLSKERIRELQQQIEDLQK 529
Query: 339 ASRAQVSTAEKE-REELKNRLHWQMKRLTENFEQAQ 373
+ + Q S +E E +LK +L M++LTE E+ Q
Sbjct: 530 SLQEQGSKSEGESSSKLKQKLEAHMEKLTEVHEELQ 565
>AF022655-1|AAC06349.1| 2442|Homo sapiens cep250 centrosome associated
protein protein.
Length = 2442
Score = 47.6 bits (108), Expect = 8e-05
Identities = 79/388 (20%), Positives = 156/388 (40%), Gaps = 13/388 (3%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYR--EAREE-IDEL 75
Q +++L ELE K + + + + K+Q E L++ + E +++ I EL
Sbjct: 1520 QRNVLEHQLLELEKKDQMIESQRGQVQDLKKQLVTLECLALELEENHHKMECQQKLIKEL 1579
Query: 76 RTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEK 135
+ Q L + + Q ++ Q Q +T ++ ++ Q VK + +E+
Sbjct: 1580 EGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQ-REQ 1638
Query: 136 LQELAPIPD-LLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLV 194
++EL + L + + R ++ + + +Q R+ E + I L
Sbjct: 1639 IEELQRQKEHLTQDLERRDQELMLQKERIQVLEDQRTRQTKILEEDLEQIKLSLRERGRE 1698
Query: 195 TTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQ 254
T TQ L Q ++E G+G L H L +K E ++ + L + Q
Sbjct: 1699 LT---TQRQLM-QERAEEGKGPSKAQRGSLEHMKLILRDKEKEVECQQEHIHELQELKDQ 1754
Query: 255 LAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQR 314
L + L ++ + + E+ + +++LQE + L DEA RAL +
Sbjct: 1755 LEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQ 1814
Query: 315 AHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQL 374
++ E +++ Q + ER + A E+ LK R H +++ E + +
Sbjct: 1815 RDQELEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKER-HGELQDHKEQARRLEE 1873
Query: 375 RILGLQTQVQSLRRTASSTGDGDGENQE 402
+ +VQ+L GD E++E
Sbjct: 1874 ELAVEGRRVQALEEV---LGDLRAESRE 1898
Score = 39.5 bits (88), Expect = 0.021
Identities = 89/401 (22%), Positives = 162/401 (40%), Gaps = 42/401 (10%)
Query: 22 ETQNKLRELEMKFEGLATHTNM--LMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLM 79
+TQ +L + + E L + L + Q A ++ AR+ D+L L
Sbjct: 936 QTQKELADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAARQHRDDLAALQ 995
Query: 80 KEQNDQLQD-----YRVKYLQ--------AQQLVEEQRRQXXXXXXXNTRISEQINLEIQ 126
+E + LQD +V+ L+ +Q+LVE++ ++ RI +++ E
Sbjct: 996 EESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKELEREKA 1055
Query: 127 RVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFR 186
+ L EK Q L + + Q L +Q A+ ++L+ ++ R++V +
Sbjct: 1056 SLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQMELLRQEV----K 1111
Query: 187 YLYSLYLVTTMTLTQEDLFGQSQSEIGRGN--KDQTVHVLLHNSLKPPEKPPERGGDEKQ 244
+ +L L +E + R + + LH L+ E E E+Q
Sbjct: 1112 EKEADFLAQEAQLLEELEASHITEQQLRASLWAQEAKAAQLHLRLRSTESQLEALAAEQQ 1171
Query: 245 MALLNQRISQLAENNISLKSEIERLKASVI--RTEESALANEK----RLQEKMHECAQL- 297
Q +QLA SL S +++ SV R E S + L+ + L
Sbjct: 1172 PGNQAQAQAQLA----SLYSALQQALGSVCESRPELSGGGDSAPSVWGLEPDQNGARSLF 1227
Query: 298 --GGELDRTRDEA-SRALQRAHE---QTETVRKCLQTTVAELERQLAASRAQVSTAEKER 351
G L EA + AL + H+ +T+ R L+ V +LE +L + A+ S E
Sbjct: 1228 KRGPLLTALSAEAVASALLKLHQDLWKTQQTRDVLRDQVQKLEERLTDTEAEKSQVHTEL 1287
Query: 352 EELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRRTASS 392
++L+ +L Q + +E Q L++++ L T +S
Sbjct: 1288 QDLQRQLS-QNQEEKSKWEGKQ---NSLESELMELHETMAS 1324
Score = 36.3 bits (80), Expect = 0.20
Identities = 32/142 (22%), Positives = 62/142 (43%), Gaps = 4/142 (2%)
Query: 248 LNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDE 307
LNQ++ QL E N S+ S +E + + + EKR + + L +L + +E
Sbjct: 615 LNQQLLQLEEENQSVCSRMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKA-EE 673
Query: 308 ASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKE---REELKNRLHWQMKR 364
A LQ + ++ +Q ++E Q A+ Q+ +E +EE+ R + +
Sbjct: 674 AGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEA 733
Query: 365 LTENFEQAQLRILGLQTQVQSL 386
L ++R+ ++ Q L
Sbjct: 734 LVREKAALEVRLQAVERDRQDL 755
Score = 35.1 bits (77), Expect = 0.46
Identities = 88/400 (22%), Positives = 165/400 (41%), Gaps = 38/400 (9%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEID-ELRT 77
+ E Q KL E + E T L +E ++EV RA+++ RE+ E+R
Sbjct: 688 EKEEIQKKLSESRHQQEAATTQLEQL--HQEAKRQEEVLARAVQEKEALVREKAALEVRL 745
Query: 78 LMKEQNDQLQDYRVKYLQ-AQQLVEEQRRQXXXXXXXNTRISEQINLEIQRV---KLKFQ 133
E++ Q +++ L A++L+E + Q+ ++IQ V K Q
Sbjct: 746 QAVERDRQDLAAQLQGLSSAKELLESSLFEAQQQNSVIDEPQGQLEVQIQTVTQAKEVIQ 805
Query: 134 EKLQELAPIPDLLKATQMRLKDAQQAQ-AIAEHNAEQLARELNCAREKVVHIFRYLYSL- 191
+++ L D ++ + +DA Q A AE + + A EK V+ R +
Sbjct: 806 GEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLREKWEKE 865
Query: 192 --YLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGG-------DE 242
+ + E L + + E+ K+Q + + + E+ E
Sbjct: 866 RSWHQQELAKALESL-EREKMELEMRLKEQQTEMEAIQAQREEERTQAESALCQMQLETE 924
Query: 243 KQMALLNQRISQLAENNISLKSEIERL----KASVIRTEESALANEKRLQEKMHECAQLG 298
K+ L + + Q + ++ERL K ++ +E+ + +LQE E +
Sbjct: 925 KERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAA 984
Query: 299 GELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKE-REELK-- 355
+ RD+ + ALQ + LQ V +L+ QL A E+E +E+L+
Sbjct: 985 RQ---HRDDLA-ALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRET 1040
Query: 356 ---NRLHWQMKR----LTENFEQAQLRILGLQTQVQSLRR 388
NR+ +++R LT + + + R+L LQ + S+R+
Sbjct: 1041 QEYNRIQKELEREKASLTLSLMEKEQRLLVLQ-EADSIRQ 1079
Score = 33.9 bits (74), Expect = 1.1
Identities = 70/327 (21%), Positives = 129/327 (39%), Gaps = 28/327 (8%)
Query: 49 EQAFEQEVNVRALKQCYREA----REEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQR 104
EQA E EV RAL+ + +A +E EL L E +A+ L E
Sbjct: 1912 EQAQEHEVETRALQDSWLQAQAVLKERDQELEALRAESQSSRHQEEAARARAEALQEALG 1971
Query: 105 RQXXXXXXXNTRISEQINLE--IQRVKLKFQEKLQEL-APIPDLLKATQMRLKDAQQAQA 161
+ + EQ L ++ Q L A L +A +++ + Q
Sbjct: 1972 KAHAALQGKEQHLLEQAELSRSLEASTATLQASLDACQAHSRQLEEALRIQEGEIQDQDL 2031
Query: 162 IAEHNAEQLARELNCAREKVVH------IFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRG 215
+ + +QL + L E++ H + + + M +++L + + E RG
Sbjct: 2032 RYQEDVQQLQQALAQRDEELRHQQEREQLLEKSLAQRVQENMIQEKQNLGLEREEEEIRG 2091
Query: 216 NKDQTVHVLLHNSLKPPEKPPERGGDEKQ-MALL--NQRISQLAENNISLKS-------E 265
+ L + K E R ++ + L + + S + E ++ L S E
Sbjct: 2092 LHQSVRELQLTLAQKEQEILELRETQQRNNLEALPHSHKTSPMEEQSLKLDSLEPRLQRE 2151
Query: 266 IERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEA----SRALQRAHEQTET 321
+ERL+A++ +TE + ++ Q+ AQ + ++ A + L+R EQ +
Sbjct: 2152 LERLQAALRQTEAREIEWREKAQDLALSLAQTKASVSSLQEVAMFLQASVLERDSEQ-QR 2210
Query: 322 VRKCLQTTVAELERQLAASRAQVSTAE 348
++ L+ T LE++ S STAE
Sbjct: 2211 LQDELELTRRALEKERLHSPGATSTAE 2237
Score = 31.9 bits (69), Expect = 4.3
Identities = 35/144 (24%), Positives = 62/144 (43%), Gaps = 11/144 (7%)
Query: 250 QRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGE---LDRTRD 306
Q + L + + + L+ + EE A +RLQ+ E L G+ L D
Sbjct: 400 QAVQDLRQQLAGCQEAVNLLQQQHDQWEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVD 459
Query: 307 EASRA---LQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMK 363
S+ LQ+A E+ + L+ L R + Q +A+ ++EE + LH ++
Sbjct: 460 SLSKERELLQKAREELRQQLEVLEQEAWRLRRVNVELQLQGDSAQGQKEEQQEELHLAVR 519
Query: 364 RLTENFEQAQLRILGLQT-QVQSL 386
E+ Q ++GL+ Q +SL
Sbjct: 520 ER----ERLQEMLMGLEAKQSESL 539
Score = 31.1 bits (67), Expect = 7.4
Identities = 72/339 (21%), Positives = 133/339 (39%), Gaps = 18/339 (5%)
Query: 54 QEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYL-QAQQLVEEQRRQXXXXXX 112
++ + AL+Q +EA+ E EL M+ ++++ +L Q QL+EE
Sbjct: 1078 RQQELSALRQDMQEAQGEQKELSAQMELLRQEVKEKEADFLAQEAQLLEELEASHITEQQ 1137
Query: 113 XNTRISEQINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQ-QAQAIAEHNAEQLA 171
+ Q + ++ L+ + +L + L A Q AQ QAQ + ++A Q A
Sbjct: 1138 LRASLWAQ-EAKAAQLHLRLRSTESQL----EALAAEQQPGNQAQAQAQLASLYSALQQA 1192
Query: 172 RELNC-AREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVL-LHNSL 229
C +R ++ S++ + LF + + +L LH L
Sbjct: 1193 LGSVCESRPELSGGGDSAPSVWGLEPDQNGARSLFKRGPLLTALSAEAVASALLKLHQDL 1252
Query: 230 KPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQE 289
++ + D+ Q L +R++ + +E++ L+ + + +E E +
Sbjct: 1253 WKTQQTRDVLRDQVQK--LEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNS 1310
Query: 290 KMHECAQLGGELDRTRDEASRA-LQRAHEQTE-----TVRKCLQTTVAELERQLAASRAQ 343
E +L + + RA LQR Q E ++ L V L+ + +RAQ
Sbjct: 1311 LESELMELHETMASLQSRLRRAELQRMEAQGERELLQAAKENLTAQVEHLQAAVVEARAQ 1370
Query: 344 VSTAEKEREELKNRLHWQMKRLTENFEQAQLRILGLQTQ 382
S A E+L+ +K E E + R LQ Q
Sbjct: 1371 ASAAGILEEDLRT-ARSALKLKNEEVESERERAQALQEQ 1408
>AB209996-1|BAE06078.1| 2585|Homo sapiens CENPE variant protein
protein.
Length = 2585
Score = 47.6 bits (108), Expect = 8e-05
Identities = 52/322 (16%), Positives = 147/322 (45%), Gaps = 12/322 (3%)
Query: 53 EQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXX 112
E++ ++ + +E +E ID+LR ++ E+ +++ + + + ++ Q +
Sbjct: 1698 EKQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELR 1757
Query: 113 -XNTRISEQINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLA 171
+ + EQ I +++ EK +L+ + L+ + +L++ Q EH L
Sbjct: 1758 IAHMHLKEQQET-IDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQELKANEHQLITLK 1816
Query: 172 RELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLH-NSLK 230
+++N ++KV + L ++TL++ ++ + ++ N ++ V+ ++L+
Sbjct: 1817 KDVNETQKKVSEM-EQLKKQIKDQSLTLSKLEIENLNLAQKLHENLEEMKSVMKERDNLR 1875
Query: 231 PPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEK 290
E+ + D+ L + + + ++ ++ E++ + +E+ +++ EK
Sbjct: 1876 RVEETLKLERDQ-----LKESLQETKARDLEIQQELKTARMLSKEHKETVDKLREKISEK 1930
Query: 291 MHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKE 350
+ + + +LD+++DE + R + Q + ++ L L L +++ K
Sbjct: 1931 TIQISDIQKDLDKSKDELQKKQDRQNHQVKPEKRLLSDGQQHLTESLREKCSRIKELLKR 1990
Query: 351 REELKNRLHWQ-MKRLTENFEQ 371
E+ + H++ + RL+ + E+
Sbjct: 1991 YSEMDD--HYECLNRLSLDLEK 2010
Score = 38.3 bits (85), Expect = 0.049
Identities = 33/155 (21%), Positives = 68/155 (43%), Gaps = 5/155 (3%)
Query: 248 LNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDE 307
+NQ I L++ S + LK + + + +QE+++E QL +L+ RD
Sbjct: 823 MNQEIVNLSKEAQKFDSSLGALKTELSYKTQELQEKTREVQERLNEMEQLKEQLE-NRDS 881
Query: 308 ASRALQRAHEQTETVRKCLQT--TVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRL 365
+ ++R E+T K QT V L ++ + + + ER++LK+ +H +
Sbjct: 882 TLQTVER--EKTLITEKLQQTLEEVKTLTQEKDDLKQLQESLQIERDQLKSDIHDTVNMN 939
Query: 366 TENFEQAQLRILGLQTQVQSLRRTASSTGDGDGEN 400
+ EQ + + L+ +++ S + N
Sbjct: 940 IDTQEQLRNALESLKQHQETINTLKSKISEEVSRN 974
Score = 37.5 bits (83), Expect = 0.086
Identities = 69/384 (17%), Positives = 157/384 (40%), Gaps = 21/384 (5%)
Query: 21 RETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMK 80
+E+ ++++ + + + L +L +Q E N++ + + E EE+ +K
Sbjct: 1411 QESHDEMKSVAKEKDDLQRLQEVLQSESDQLKE---NIKEIVAKHLETEEELKVAHCCLK 1467
Query: 81 EQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQ-EKLQEL 139
EQ + + + RV + + + ++Q N ++ +I EI + +F +++ E+
Sbjct: 1468 EQEETINELRVNLSEKETEISTIQKQ---LEAINDKLQNKIQ-EIYEKEEQFNIKQISEV 1523
Query: 140 APIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTL 199
+ LK + K A E +L L ++E++ + + + V
Sbjct: 1524 QEKVNELKQFKEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQ 1583
Query: 200 TQEDLFGQSQSEI---GRGNKDQTVHVLLHNSL-KPPEKPPERGGDEKQMALLNQRISQL 255
+ D ++ EI + ++++ L ++ + EK E ++Q + +
Sbjct: 1584 IERDQLKENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKLNLENI 1643
Query: 256 AENNISLKSEIERLKASVIRTEESALANEKRLQEKMH-ECAQLGGELDRTRDEASRALQR 314
NI L ++I +R+ + + ++E + E QL L R+ +R L++
Sbjct: 1644 ETENIRL-TQILHENLEEMRSVTKERDDLRSVEETLKVERDQLKENL---RETITRDLEK 1699
Query: 315 AHEQTETVRKCL---QTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQ 371
E+ + V L Q T+ +L ++ ++S +K+ E + L Q ++ E
Sbjct: 1700 -QEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRI 1758
Query: 372 AQLRILGLQTQVQSLRRTASSTGD 395
A + + Q + LR S D
Sbjct: 1759 AHMHLKEQQETIDKLRGIVSEKTD 1782
Score = 33.1 bits (72), Expect = 1.8
Identities = 32/159 (20%), Positives = 80/159 (50%), Gaps = 13/159 (8%)
Query: 19 QHRETQNKLREL-EMKFEGLAT------HTNMLMGSKEQAFEQEVNVRALKQCYREAREE 71
+H+ET +KLR + K ++ H+N + +++ ++E+ + + +E +E
Sbjct: 1712 EHQETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHMH--LKEQQET 1769
Query: 72 IDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLK 131
ID+LR ++ E+ D+L + + + ++E+ ++ + + +N E Q+ K+
Sbjct: 1770 IDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQELKANEHQLITLKKDVN-ETQK-KVS 1827
Query: 132 FQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQL 170
E+L++ L +++ +++ AQ + E N E++
Sbjct: 1828 EMEQLKKQIK-DQSLTLSKLEIENLNLAQKLHE-NLEEM 1864
>AB051536-1|BAB21840.2| 1047|Homo sapiens KIAA1749 protein protein.
Length = 1047
Score = 47.6 bits (108), Expect = 8e-05
Identities = 92/395 (23%), Positives = 167/395 (42%), Gaps = 35/395 (8%)
Query: 17 RCQHRETQNKLRELEMKFEGLATHTNMLMGSKEQAF---EQEVNVRALKQCYREAREEID 73
R + RE + EL + L ++L+ +EQ ++E + ALK +E D
Sbjct: 464 RSEDREKGALIEELLQAKQDLQ---DLLIAKEEQEDLLRKRERELTALKGALKEEVSSHD 520
Query: 74 ELRTLMKEQND-QLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKL-- 130
+ +KEQ D +LQ R +A + VE NT +Q E+ RVKL
Sbjct: 521 QEMDKLKEQYDAELQALRESVEEATKNVE------VLASRSNTSEQDQAGTEM-RVKLLQ 573
Query: 131 KFQEKLQELAP-IPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLY 189
+ EKLQ + + + Q +++D + +A A+ ++ E+ E +VH +
Sbjct: 574 EENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQLEEALVHARKEEK 633
Query: 190 SLY-----LVTTMTLTQEDLFG--QSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDE 242
L + Q +L Q Q ++ K+++ LK E ER
Sbjct: 634 EAVSARRALENELEAAQGNLSQTTQEQKQLSEKLKEESEQKEQLRRLKN-EMENERWHLG 692
Query: 243 KQMALLNQRISQLAE----NNISLKSEIERLKASVIR--TEESALANEKRLQ-EKMHECA 295
K + L + ++ + E + + L+++++ K R E EK L+ EK A
Sbjct: 693 KTIEKLQKEMADIVEASRTSTLELQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTA 752
Query: 296 QLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAAS---RAQVSTAEKERE 352
+ R +E R QRA ++ T R+ L+ T+ +LE +L A + S K+ E
Sbjct: 753 MKMQDEMRLMEEELRDYQRAQDEALTKRQLLEQTLKDLEYELEAKSHLKDDRSRLVKQME 812
Query: 353 ELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLR 387
+ ++L +++ N + RI + Q++ +R
Sbjct: 813 DKVSQLEMELEEERNNSDLLSERISRSREQMEQVR 847
Score = 45.6 bits (103), Expect = 3e-04
Identities = 76/390 (19%), Positives = 147/390 (37%), Gaps = 20/390 (5%)
Query: 21 RETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDE-LRTLM 79
R +N+L + L ++ EQ+ +R LK R + + + L
Sbjct: 640 RALENELEAAQGNLSQTTQEQKQLSEKLKEESEQKEQLRRLKNEMENERWHLGKTIEKLQ 699
Query: 80 KEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQEL 139
KE D ++ R L+ Q ++E + + R ++ LE ++ +L + E+
Sbjct: 700 KEMADIVEASRTSTLELQNQLDEYKEKNRRELAEMQRQLKEKTLEAEKSRLTAMKMQDEM 759
Query: 140 APIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCA---REKVVHIFRYLYSLYLVTT 196
+ + L+ Q +A + + E + L EL ++ + + +
Sbjct: 760 RLMEEELRDYQRAQDEALTKRQLLEQTLKDLEYELEAKSHLKDDRSRLVKQMEDKVSQLE 819
Query: 197 MTLTQE----DLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRI 252
M L +E DL + S R +Q + LL + ++ E+Q L RI
Sbjct: 820 MELEEERNNSDLLSERISR-SREQMEQVRNELLQERAARQDLECDKISLERQNKDLKSRI 878
Query: 253 SQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQL---GGELDRTRDEAS 309
L S +S E L V++ E E RL+ + + A L L+R E
Sbjct: 879 IHLEG---SYRSSKEGL---VVQMEARIAELEDRLESEERDRANLQLSNRRLERKVKELV 932
Query: 310 RALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENF 369
+ H + L + ++RQ+ + ++ E +++L+ L QM + E+
Sbjct: 933 MQVDDEHLSLTDQKDQLSLRLKAMKRQVEEAEEEIDRLESSKKKLQRELEEQMD-MNEHL 991
Query: 370 EQAQLRILGLQTQVQSLRRTASSTGDGDGE 399
Q QL + +++ L D D +
Sbjct: 992 -QGQLNSMKKDLRLKKLPSKVLDDMDDDDD 1020
Score = 45.2 bits (102), Expect = 4e-04
Identities = 91/409 (22%), Positives = 174/409 (42%), Gaps = 43/409 (10%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQ----EVNVRALKQCYREAREEIDE 74
++ + Q + ELE + L L G + +A E E +R L++ AR+E E
Sbjct: 575 ENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQLEEALVHARKEEKE 634
Query: 75 L---RTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKL- 130
R ++ + + Q + Q Q+ + E+ ++ R+ + +E +R L
Sbjct: 635 AVSARRALENELEAAQGNLSQTTQEQKQLSEKLKEESEQKEQLRRLKNE--MENERWHLG 692
Query: 131 KFQEKLQ-ELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRY-L 188
K EKLQ E+A I + + + + L++ Q E N +LA +EK + + L
Sbjct: 693 KTIEKLQKEMADIVEASRTSTLELQN--QLDEYKEKNRRELAEMQRQLKEKTLEAEKSRL 750
Query: 189 YSLYLVTTMTLTQEDL--FGQSQSEI--GRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQ 244
++ + M L +E+L + ++Q E R +QT+ L + +R KQ
Sbjct: 751 TAMKMQDEMRLMEEELRDYQRAQDEALTKRQLLEQTLKDLEYELEAKSHLKDDRSRLVKQ 810
Query: 245 MA------------------LLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKR 286
M LL++RIS+ E +++E+ + +A+ E ++ E++
Sbjct: 811 MEDKVSQLEMELEEERNNSDLLSERISRSREQMEQVRNELLQERAARQDLECDKISLERQ 870
Query: 287 LQEKMHECAQLGGELDRTRD------EASRA-LQRAHEQTETVRKCLQTTVAELERQLAA 339
++ L G +++ EA A L+ E E R LQ + LER++
Sbjct: 871 NKDLKSRIIHLEGSYRSSKEGLVVQMEARIAELEDRLESEERDRANLQLSNRRLERKVKE 930
Query: 340 SRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRR 388
QV + K++L ++K + E+A+ I L++ + L+R
Sbjct: 931 LVMQVDDEHLSLTDQKDQLSLRLKAMKRQVEEAEEEIDRLESSKKKLQR 979
Score = 38.3 bits (85), Expect = 0.049
Identities = 67/352 (19%), Positives = 144/352 (40%), Gaps = 25/352 (7%)
Query: 48 KEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQX 107
KE+ N+ L+ + E EE L+ ++E +L+ + Q + E+ + +
Sbjct: 386 KEERERMRANLEELRSQHNEKVEENSTLQQRLEESEGELRKNLEELFQVKMEREQHQTEI 445
Query: 108 XXXXXXNTRISEQINL----EIQRVKLKFQEKLQELAPIPDLLKATQ----MRLKDAQQA 159
+ + ++++ E + +E LQ + DLL A + + K ++
Sbjct: 446 RDLQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEEQEDLLRKREREL 505
Query: 160 QAIAEHNAEQLA---RELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQ-SEIGRG 215
A+ E+++ +E++ +E+ + L V T E L +S SE +
Sbjct: 506 TALKGALKEEVSSHDQEMDKLKEQYDAELQALRES--VEEATKNVEVLASRSNTSEQDQA 563
Query: 216 NKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIR 275
+ V +L + K + E E+++A L ++I L + K +++ + + +
Sbjct: 564 GTEMRVKLLQEENEKLQGRSEEL---ERRVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQ 620
Query: 276 TEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELER 335
EE+ + K +E + L EL+ + S+ Q + +E +++ +E +
Sbjct: 621 LEEALVHARKEEKEAVSARRALENELEAAQGNLSQTTQEQKQLSEKLKE-----ESEQKE 675
Query: 336 QLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLR 387
QL R + E ER L + K + + E ++ L LQ Q+ +
Sbjct: 676 QL---RRLKNEMENERWHLGKTIEKLQKEMADIVEASRTSTLELQNQLDEYK 724
>AB015617-1|BAA88763.1| 948|Homo sapiens ELKS protein.
Length = 948
Score = 47.6 bits (108), Expect = 8e-05
Identities = 81/382 (21%), Positives = 157/382 (41%), Gaps = 36/382 (9%)
Query: 21 RETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMK 80
+E K EL L T TN SK+ + ++ A +Q + E+D LR ++
Sbjct: 445 QELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLE 504
Query: 81 EQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRI---SEQINL---EIQRVKLKFQE 134
E+ L K Q Q + EE+ Q + ++N+ +I+ ++ + ++
Sbjct: 505 EKETMLNK---KTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRD 561
Query: 135 KLQELAPIPDLLKA-------TQMRLKDAQQAQAIAEHNAEQLARELN-CAREKVVHIFR 186
K ++++ + + +K+ T L ++A A E E+L + + REK I
Sbjct: 562 KEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDN 621
Query: 187 YLYSLY-LVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQM 245
Y L L ++L Q DL S+ E + + L + LK + ++
Sbjct: 622 YKKDLKDLKEKVSLLQGDL---SEKEASLLDLKEHASSLASSGLK----------KDSRL 668
Query: 246 ALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTR 305
L + Q E + ++S++++ + + S ++ R+Q E + E + +
Sbjct: 669 KTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSD-RIQHLEREITRYKDESSKAQ 727
Query: 306 DEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRL 365
E R L+ E E + +AELE + + QV K+ LK++ + K+
Sbjct: 728 AEVDRLLEILKE-VENEKNDKDKKIAELE---SLTSRQVKDQNKKVANLKHKEQVEKKKS 783
Query: 366 TENFEQAQLRILGLQTQVQSLR 387
+ E+A+ R L Q L+
Sbjct: 784 AQMLEEARRREDNLNDSSQQLQ 805
Score = 43.2 bits (97), Expect = 0.002
Identities = 77/368 (20%), Positives = 154/368 (41%), Gaps = 33/368 (8%)
Query: 19 QHRETQNKLRELEMKFEGL---ATHTNMLMGSKEQAF-EQEVNVRALK-QCYREAREEID 73
Q R+ + ++ L+ + + L T+T+ + + E+A E+E + LK Q R+ RE+ +
Sbjct: 558 QLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQE 617
Query: 74 ELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLE--IQRVKLK 131
E+ K+ D + +V LQ L E++ ++ S + + ++ +++
Sbjct: 618 EIDNYKKDLKDLKE--KVSLLQGD-LSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIA 674
Query: 132 FQEKLQELAPIPDLLKATQMRLKDAQQAQAIAE---HNAEQLARELNCAREKVVHIFRYL 188
++K +E + LK +A+ + +++ H ++ R + + + + R L
Sbjct: 675 LEQKKEECLKMESQLKKAHEAALEARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLL 734
Query: 189 YSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHV--LLHNSLKPPEKPPERGGDEKQMA 246
L V ++ + +S R KDQ V L H +K + + ++
Sbjct: 735 EILKEVENEKNDKDKKIAELESLTSRQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRRE 794
Query: 247 -LLNQRISQLAENNI-----SLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGE 300
LN QL + +K E+E +KA + T++S E L A+
Sbjct: 795 DNLNDSSQQLQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLR---AERRKH 851
Query: 301 LDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHW 360
L+ + AL A + + +A LE + + Q A +RE K+RL
Sbjct: 852 LEEVLEMKQEALLAAISEKD-------ANIALLELSSSKKKTQEEVAALKRE--KDRLVQ 902
Query: 361 QMKRLTEN 368
Q+K+ T+N
Sbjct: 903 QLKQQTQN 910
Score = 38.7 bits (86), Expect = 0.037
Identities = 33/154 (21%), Positives = 66/154 (42%), Gaps = 4/154 (2%)
Query: 242 EKQMALLNQRISQL---AENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLG 298
E++ +LN++ Q+ AE + EI LK + E +K+++ +
Sbjct: 504 EEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKE 563
Query: 299 GELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRL 358
++ ++ ++LQ T+T L+ +AE ER + + Q E+E++E +
Sbjct: 564 KQMSSLKERV-KSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNY 622
Query: 359 HWQMKRLTENFEQAQLRILGLQTQVQSLRRTASS 392
+K L E Q + + + L+ ASS
Sbjct: 623 KKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASS 656
>BC130453-1|AAI30454.1| 1726|Homo sapiens ANKRD26 protein protein.
Length = 1726
Score = 47.2 bits (107), Expect = 1e-04
Identities = 34/128 (26%), Positives = 67/128 (52%), Gaps = 8/128 (6%)
Query: 272 SVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVA 331
S+++ +++AL+ E+ L+ K + C L ++ + D+ + LQR +T+ ++ L+
Sbjct: 740 SLLKIQDAALSCERLLELKKNHCELLTVKIKKMEDKVN-VLQRELSETKEIKSQLEHQKV 798
Query: 332 ELERQLAASRAQVSTAEKER---EELKNRLHWQMKRLTENF----EQAQLRILGLQTQVQ 384
E ER+L + R ++ E++R + L ++ Q++R E + E Q L LQT
Sbjct: 799 EWERELCSLRFSLNQEEEKRRNADTLYEKIREQLRRKEEQYRKEVEVKQQLELSLQTLEM 858
Query: 385 SLRRTASS 392
LR S+
Sbjct: 859 ELRTVKSN 866
Score = 31.9 bits (69), Expect = 4.3
Identities = 28/151 (18%), Positives = 64/151 (42%), Gaps = 6/151 (3%)
Query: 22 ETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKE 81
+TQ +++E+E K++ N +G +E E+ +++ R+ ++ ++
Sbjct: 1119 QTQCQMKEMEQKYQNEQVKVNKYIGKQESVEERLSQLQSENMLLRQQLDDAHNKADNKEK 1178
Query: 82 QNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAP 141
+QD + Q+L E +Q N + + N +K + + E A
Sbjct: 1179 TVINIQDQ--FHAIVQKLQAESEKQSLLLEERNKELISECN----HLKERQYQYENEKAE 1232
Query: 142 IPDLLKATQMRLKDAQQAQAIAEHNAEQLAR 172
+++ Q L D + Q+++E + E +R
Sbjct: 1233 REVVVRQLQQELADTLKKQSMSEASLEVTSR 1263
>BC089391-1|AAH89391.1| 466|Homo sapiens CCDC19 protein protein.
Length = 466
Score = 47.2 bits (107), Expect = 1e-04
Identities = 84/374 (22%), Positives = 171/374 (45%), Gaps = 35/374 (9%)
Query: 25 NKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREE---IDELRTLMKE 81
NKLR +E + E L + +++ +K A ++ + +Q +E E +D++ + ++
Sbjct: 96 NKLR-MEQE-EELKDMSKIILNAKCHAI-RDAQILEKQQIQKELDTEEKRLDQMMEVERQ 152
Query: 82 QNDQLQDYRVKYLQAQQLVEEQRR---QXXXXXXXNTRISEQINLEIQRVKLKFQEKLQE 138
++ Q Q+ ++ + ++ + +R+ Q + ++EQ E +++ L++ E+LQE
Sbjct: 153 KSIQRQE-ELERKRREERIRGRRQIVEQMEKNQEERSLLAEQREQEKEQM-LEYMEQLQE 210
Query: 139 LAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMT 198
+ D+ + Q +LK + + I + N +Q A L A+EK+ + T
Sbjct: 211 -EDLKDMERRQQQKLKMQAEIKRINDENQKQKAELL--AQEKLAD-----QMVMEFTKKK 262
Query: 199 LTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAEN 258
+ +E F Q I R K++ + L K + E Q AL +R ++A+
Sbjct: 263 MAREAEFEAEQERIRR-EKEKEIARLRAMQEKAQDYQAE------QDALRAKRNQEVADR 315
Query: 259 NISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQ 318
K + K + E A + RL++ + L ++ R RDE R L+ EQ
Sbjct: 316 EWRRKEKENARK----KMETEAELRKSRLEQVAFKEHALAVQVQRDRDEFERILRAQREQ 371
Query: 319 TETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRL--HWQMKRLTENFEQAQLRI 376
E R L+ R A+ + E +++E++NR+ + +RL E ++ + RI
Sbjct: 372 IEKER--LEEEKKATGRLQHANELRRQVRENQQKEVQNRIATFEEGRRLKEEAQKRRERI 429
Query: 377 LGL-QTQVQSLRRT 389
+ + +++ LR T
Sbjct: 430 DEIKRKKLEELRAT 443
Score = 46.4 bits (105), Expect = 2e-04
Identities = 79/394 (20%), Positives = 163/394 (41%), Gaps = 47/394 (11%)
Query: 28 RELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYRE-AREEIDELRTLMKEQNDQL 86
+E E + + T +M KE + + L++ +E A+ + L EQ ++L
Sbjct: 48 KEKEATMDAVMTRKK-IMKQKEMVWNNNKKLSDLEEVAKERAQNLLQRANKLRMEQEEEL 106
Query: 87 QDYRVKYLQAQ-------QLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQEL 139
+D L A+ Q++E+Q+ Q R+ + + +E Q+ ++ QE+L+
Sbjct: 107 KDMSKIILNAKCHAIRDAQILEKQQIQKELDTEEK-RLDQMMEVERQK-SIQRQEELER- 163
Query: 140 APIPDLLKATQMRLKDAQQAQAIAEHNAEQ---LARELNCAREKVVHIFRYLYSLYLVTT 196
K + R++ +Q E N E+ LA + +E+++ L L
Sbjct: 164 -------KRREERIRGRRQIVEQMEKNQEERSLLAEQREQEKEQMLEYMEQLQEEDLKDM 216
Query: 197 MTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLA 256
Q+ L + Q+EI R N + ++ E EK L +Q + +
Sbjct: 217 ERRQQQKL--KMQAEIKRINDENQ------------KQKAELLAQEK---LADQMVMEFT 259
Query: 257 ENNISLKSEIERLKASVIRTEESALANEKRLQEKM--HECAQLGGELDRTRDEASRALQR 314
+ ++ ++E E + + R +E +A + +QEK ++ Q R ++ A R +R
Sbjct: 260 KKKMAREAEFEAEQERIRREKEKEIARLRAMQEKAQDYQAEQDALRAKRNQEVADREWRR 319
Query: 315 AHEQTETVRKCLQTTV----AELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFE 370
++ E RK ++T + LE+ A +++R+E + L Q +++ +
Sbjct: 320 --KEKENARKKMETEAELRKSRLEQVAFKEHALAVQVQRDRDEFERILRAQREQIEKERL 377
Query: 371 QAQLRILGLQTQVQSLRRTASSTGDGDGENQECT 404
+ + + G LRR + +N+ T
Sbjct: 378 EEEKKATGRLQHANELRRQVRENQQKEVQNRIAT 411
>AL590560-10|CAH71107.1| 551|Homo sapiens coiled-coil domain
containing 19 protein.
Length = 551
Score = 47.2 bits (107), Expect = 1e-04
Identities = 84/374 (22%), Positives = 171/374 (45%), Gaps = 35/374 (9%)
Query: 25 NKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREE---IDELRTLMKE 81
NKLR +E + E L + +++ +K A ++ + +Q +E E +D++ + ++
Sbjct: 181 NKLR-MEQE-EELKDMSKIILNAKCHAI-RDAQILEKQQIQKELDTEEKRLDQMMEVERQ 237
Query: 82 QNDQLQDYRVKYLQAQQLVEEQRR---QXXXXXXXNTRISEQINLEIQRVKLKFQEKLQE 138
++ Q Q+ ++ + ++ + +R+ Q + ++EQ E +++ L++ E+LQE
Sbjct: 238 KSIQRQE-ELERKRREERIRGRRQIVEQMEKNQEERSLLAEQREQEKEQM-LEYMEQLQE 295
Query: 139 LAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMT 198
+ D+ + Q +LK + + I + N +Q A L A+EK+ + T
Sbjct: 296 -EDLKDMERRQQQKLKMQAEIKRINDENQKQKAELL--AQEKLAD-----QMVMEFTKKK 347
Query: 199 LTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAEN 258
+ +E F Q I R K++ + L K + E Q AL +R ++A+
Sbjct: 348 MAREAEFEAEQERIRR-EKEKEIARLRAMQEKAQDYQAE------QDALRAKRNQEVADR 400
Query: 259 NISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQ 318
K + K + E A + RL++ + L ++ R RDE R L+ EQ
Sbjct: 401 EWRRKEKENARK----KMETEAELRKSRLEQVAFKEHALAVQVQRDRDEFERILRAQREQ 456
Query: 319 TETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRL--HWQMKRLTENFEQAQLRI 376
E R L+ R A+ + E +++E++NR+ + +RL E ++ + RI
Sbjct: 457 IEKER--LEEEKKATGRLQHANELRRQVRENQQKEVQNRIATFEEGRRLKEEAQKRRERI 514
Query: 377 LGL-QTQVQSLRRT 389
+ + +++ LR T
Sbjct: 515 DEIKRKKLEELRAT 528
Score = 46.4 bits (105), Expect = 2e-04
Identities = 79/394 (20%), Positives = 163/394 (41%), Gaps = 47/394 (11%)
Query: 28 RELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYRE-AREEIDELRTLMKEQNDQL 86
+E E + + T +M KE + + L++ +E A+ + L EQ ++L
Sbjct: 133 KEKEATMDAVMTRKK-IMKQKEMVWNNNKKLSDLEEVAKERAQNLLQRANKLRMEQEEEL 191
Query: 87 QDYRVKYLQAQ-------QLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQEL 139
+D L A+ Q++E+Q+ Q R+ + + +E Q+ ++ QE+L+
Sbjct: 192 KDMSKIILNAKCHAIRDAQILEKQQIQKELDTEEK-RLDQMMEVERQK-SIQRQEELER- 248
Query: 140 APIPDLLKATQMRLKDAQQAQAIAEHNAEQ---LARELNCAREKVVHIFRYLYSLYLVTT 196
K + R++ +Q E N E+ LA + +E+++ L L
Sbjct: 249 -------KRREERIRGRRQIVEQMEKNQEERSLLAEQREQEKEQMLEYMEQLQEEDLKDM 301
Query: 197 MTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLA 256
Q+ L + Q+EI R N + ++ E EK L +Q + +
Sbjct: 302 ERRQQQKL--KMQAEIKRINDENQ------------KQKAELLAQEK---LADQMVMEFT 344
Query: 257 ENNISLKSEIERLKASVIRTEESALANEKRLQEKM--HECAQLGGELDRTRDEASRALQR 314
+ ++ ++E E + + R +E +A + +QEK ++ Q R ++ A R +R
Sbjct: 345 KKKMAREAEFEAEQERIRREKEKEIARLRAMQEKAQDYQAEQDALRAKRNQEVADREWRR 404
Query: 315 AHEQTETVRKCLQTTV----AELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFE 370
++ E RK ++T + LE+ A +++R+E + L Q +++ +
Sbjct: 405 --KEKENARKKMETEAELRKSRLEQVAFKEHALAVQVQRDRDEFERILRAQREQIEKERL 462
Query: 371 QAQLRILGLQTQVQSLRRTASSTGDGDGENQECT 404
+ + + G LRR + +N+ T
Sbjct: 463 EEEKKATGRLQHANELRRQVRENQQKEVQNRIAT 496
>AL162272-4|CAC19649.1| 1710|Homo sapiens novel protein protein.
Length = 1710
Score = 47.2 bits (107), Expect = 1e-04
Identities = 34/128 (26%), Positives = 67/128 (52%), Gaps = 8/128 (6%)
Query: 272 SVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVA 331
S+++ +++AL+ E+ L+ K + C L ++ + D+ + LQR +T+ ++ L+
Sbjct: 724 SLLKIQDAALSCERLLELKKNHCELLTVKIKKMEDKVN-VLQRELSETKEIKSQLEHQKV 782
Query: 332 ELERQLAASRAQVSTAEKER---EELKNRLHWQMKRLTENF----EQAQLRILGLQTQVQ 384
E ER+L + R ++ E++R + L ++ Q++R E + E Q L LQT
Sbjct: 783 EWERELCSLRFSLNQEEEKRRNADTLYEKIREQLRRKEEQYRKEVEVKQQLELSLQTLEM 842
Query: 385 SLRRTASS 392
LR S+
Sbjct: 843 ELRTVKSN 850
Score = 31.9 bits (69), Expect = 4.3
Identities = 28/151 (18%), Positives = 64/151 (42%), Gaps = 6/151 (3%)
Query: 22 ETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKE 81
+TQ +++E+E K++ N +G +E E+ +++ R+ ++ ++
Sbjct: 1103 QTQCQMKEMEQKYQNEQVKVNKYIGKQESVEERLSQLQSENMLLRQQLDDAHNKADNKEK 1162
Query: 82 QNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAP 141
+QD + Q+L E +Q N + + N +K + + E A
Sbjct: 1163 TVINIQDQ--FHAIVQKLQAESEKQSLLLEERNKELISECN----HLKERQYQYENEKAE 1216
Query: 142 IPDLLKATQMRLKDAQQAQAIAEHNAEQLAR 172
+++ Q L D + Q+++E + E +R
Sbjct: 1217 REVVVRQLQQELADTLKKQSMSEASLEVTSR 1247
>AK128577-1|BAC87508.1| 1080|Homo sapiens protein ( Homo sapiens
cDNA FLJ46736 fis, clone TRACH3020769, weakly similar
to Myosin heavy chain, nonmuscle type B. ).
Length = 1080
Score = 47.2 bits (107), Expect = 1e-04
Identities = 34/128 (26%), Positives = 67/128 (52%), Gaps = 8/128 (6%)
Query: 272 SVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVA 331
S+++ +++AL+ E+ L+ K + C L ++ + D+ + LQR +T+ ++ L+
Sbjct: 281 SLLKIQDAALSCERLLELKKNHCELLTVKIKKMEDKVN-VLQRELSETKEIKSQLEHQKV 339
Query: 332 ELERQLAASRAQVSTAEKER---EELKNRLHWQMKRLTENF----EQAQLRILGLQTQVQ 384
E ER+L + R ++ E++R + L ++ Q++R E + E Q L LQT
Sbjct: 340 EWERELCSLRFSLNQEEEKRRNADTLYEKIREQLRRKEEQYRKEVEVKQQLELSLQTLEM 399
Query: 385 SLRRTASS 392
LR S+
Sbjct: 400 ELRTVKSN 407
Score = 32.3 bits (70), Expect = 3.2
Identities = 69/369 (18%), Positives = 149/369 (40%), Gaps = 43/369 (11%)
Query: 22 ETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKE 81
+TQ +++E+E K++ N +G +E E+ +++ R+ ++ ++
Sbjct: 660 QTQCQMKEMEQKYQNEQVKVNKYIGKQESVEERLSQLQSENMLLRQQLDDAHNKADNKEK 719
Query: 82 QNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAP 141
+QD + Q+L E +Q N + + N +K + + E A
Sbjct: 720 TVINIQDQ--FHAIVQKLQAESEKQSLLLEERNKELISECN----HLKERQYQYENEKAE 773
Query: 142 IPDLLKATQMRLKDAQQAQAIAEHNAEQLAR-ELNCAREKVVHIFRYLYSLYLVTTMTLT 200
+++ Q L D + Q+++E + E +R +N E T L
Sbjct: 774 REVVVRQLQQELADTLKKQSMSEASLEVTSRYRINLEDE----------------TQDLK 817
Query: 201 QEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQ--RISQLAEN 258
++ GQ ++++ T V ++ ++ E+ + ++ + Q +I +L +N
Sbjct: 818 KK--LGQIRNQLQEAQDRHTEAVRCAEKMQDHKQKLEKDNAKLKVTIKKQMDKIEELQKN 875
Query: 259 NISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQ 318
L A++ E+ L L++ + EC LG E+ + + L+R
Sbjct: 876 ---------LLNANLSEDEKEQLKKLMELKQSL-EC-NLGQEMKKNVE-----LEREITG 919
Query: 319 TETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQLRILG 378
+ + K + + E E + + T++ E + N+L ++ LT E A + L
Sbjct: 920 FKNLLKMTRKKLNEYENGEFSFHGDLKTSQFEMDIQINKLKHKIDDLTAELETAGSKCLH 979
Query: 379 LQTQVQSLR 387
L T+ Q L+
Sbjct: 980 LDTKNQILQ 988
>AB028997-1|BAA83026.2| 1715|Homo sapiens KIAA1074 protein protein.
Length = 1715
Score = 47.2 bits (107), Expect = 1e-04
Identities = 34/128 (26%), Positives = 67/128 (52%), Gaps = 8/128 (6%)
Query: 272 SVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVA 331
S+++ +++AL+ E+ L+ K + C L ++ + D+ + LQR +T+ ++ L+
Sbjct: 729 SLLKIQDAALSCERLLELKKNHCELLTVKIKKMEDKVN-VLQRELSETKEIKSQLEHQKV 787
Query: 332 ELERQLAASRAQVSTAEKER---EELKNRLHWQMKRLTENF----EQAQLRILGLQTQVQ 384
E ER+L + R ++ E++R + L ++ Q++R E + E Q L LQT
Sbjct: 788 EWERELCSLRFSLNQEEEKRRNADTLYEKIREQLRRKEEQYRKEVEVKQQLELSLQTLEM 847
Query: 385 SLRRTASS 392
LR S+
Sbjct: 848 ELRTVKSN 855
Score = 31.9 bits (69), Expect = 4.3
Identities = 28/151 (18%), Positives = 64/151 (42%), Gaps = 6/151 (3%)
Query: 22 ETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKE 81
+TQ +++E+E K++ N +G +E E+ +++ R+ ++ ++
Sbjct: 1108 QTQCQMKEMEQKYQNEQVKVNKYIGKQESVEERLSQLQSENMLLRQQLDDAHNKADNKEK 1167
Query: 82 QNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAP 141
+QD + Q+L E +Q N + + N +K + + E A
Sbjct: 1168 TVINIQDQ--FHAIVQKLQAESEKQSLLLEERNKELISECN----HLKERQYQYENEKAE 1221
Query: 142 IPDLLKATQMRLKDAQQAQAIAEHNAEQLAR 172
+++ Q L D + Q+++E + E +R
Sbjct: 1222 REVVVRQLQQELADTLKKQSMSEASLEVTSR 1252
>D67035-1|BAA22586.1| 973|Homo sapiens SCP-1 protein.
Length = 973
Score = 46.8 bits (106), Expect = 1e-04
Identities = 70/336 (20%), Positives = 142/336 (42%), Gaps = 30/336 (8%)
Query: 47 SKEQAFEQEVNV--RALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLV--EE 102
S ++A E+++ + + Q E +++E + + ++ ++L+ E+
Sbjct: 336 STQKALEEDLQIATNTICQLTEEKDTQMEESNKARAAHSFVVTEFETTVCSLEELLRTEQ 395
Query: 103 QRRQXXXXXXXNTRIS-EQINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQA 161
QR + + ++ + E++ + K EL + +L + L D +Q +
Sbjct: 396 QRLENYEDQLIILTMELQKTSSELEEMTKLTNNKEVELEELKKVLGEKETLLYDNKQFEK 455
Query: 162 IAEH--NAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQ 219
IAE EQ L AREK VH Y Y Y T+ + GQ +
Sbjct: 456 IAEELKGTEQELIGLLQAREKEVHDLEYSYCHYHKWTVLPKR----GQRPKLSSKRELKN 511
Query: 220 TVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEES 279
T + L + PP + + D + L NQ+ E+ I+ K + ER+ + +E+
Sbjct: 512 TEYFTLQQASPPPNELTQETSD-MTLELKNQQ-----EDIINNKKQEERMLTQIENLQET 565
Query: 280 ALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTT---VAELERQ 336
E +L+ ++ + EL + RDE L ++ E +RK ++ + EL+++
Sbjct: 566 ----ETQLRNELEYVRE---ELKQKRDEVKCKLDKSEENCNNLRKQVENKNKYIEELQQE 618
Query: 337 LAASRAQVSTAEKERE--ELK-NRLHWQMKRLTENF 369
A + + + K+ E+K N+L +++ + F
Sbjct: 619 NKALKKKGTAESKQLNVYEIKVNKLELELESAKQKF 654
Score = 32.3 bits (70), Expect = 3.2
Identities = 31/170 (18%), Positives = 80/170 (47%), Gaps = 16/170 (9%)
Query: 21 RETQNKLRELEMKFEGLATHTNM---LMGSKEQAFEQEVNVR-ALKQCYREAREEIDELR 76
+ET + EL+ + E + + ++ E E E +R L+ E +++ DE++
Sbjct: 529 QETSDMTLELKNQQEDIINNKKQEERMLTQIENLQETETQLRNELEYVREELKQKRDEVK 588
Query: 77 TLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQIN---LEIQRVKLKFQ 133
+ + + + R + + +EE +++ T S+Q+N +++ +++L+ +
Sbjct: 589 CKLDKSEENCNNLRKQVENKNKYIEELQQENKALKKKGTAESKQLNVYEIKVNKLELELE 648
Query: 134 EKLQELAPIPDLLK--------ATQMRLKDAQQAQAIAEHNAEQLARELN 175
Q+ I D + + + L++ ++A+ IA+ A +L +E++
Sbjct: 649 SAKQKFGEITDTYQKEIEDKKISEENLLEEVEKAKVIAD-EAVKLQKEID 697
>DQ139275-1|ABA43896.1| 1313|Homo sapiens Tax1-binding protein 2
protein.
Length = 1313
Score = 46.8 bits (106), Expect = 1e-04
Identities = 65/312 (20%), Positives = 131/312 (41%), Gaps = 22/312 (7%)
Query: 92 KYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDLLKATQM 151
++LQ + + +R + R ++ E + ++ + +A + ++
Sbjct: 816 EFLQELRSAQRERDELRTQTSALNRQLAEMEAERDSATSRARQLQKAVAESEEARRSVDG 875
Query: 152 RLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLY--------SLYLVTTMTLTQED 203
RL Q A+ E + + RE ++V + R L S ++ M +
Sbjct: 876 RLSGVQAELALQEESVRRSERERRATLDQVATLERSLQATESELRASQEKISKMKANETK 935
Query: 204 LFGQSQ--SEIGRGNKDQTVHVLLHNSLKPPEKPPERGG---DEKQMALLNQRIS----Q 254
L G + E+ ++ +TV + L E R G E Q L R+ Q
Sbjct: 936 LEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLGLSDREAQAQALQDRVDSLQRQ 995
Query: 255 LAENNI---SLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRA 311
+A++ + +L+ +ERL ++ + EES A +++ AQ L+ TRD+ +
Sbjct: 996 VADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSASLNSTRDK-NLH 1054
Query: 312 LQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRL-HWQMKRLTENFE 370
LQ+A E R+ LQ + + L+ +R Q S+ ++ + L+ + +++R+ +
Sbjct: 1055 LQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQRVEAEGQ 1114
Query: 371 QAQLRILGLQTQ 382
QLR + Q Q
Sbjct: 1115 LQQLREVLRQRQ 1126
Score = 43.2 bits (97), Expect = 0.002
Identities = 87/373 (23%), Positives = 157/373 (42%), Gaps = 28/373 (7%)
Query: 48 KEQAFEQEVNVRALKQCYR---EAREEIDELRTLMKEQNDQLQDYRVKYLQA----QQLV 100
+E EQEV + L+ R +A+E +++ ++ + QLQ+ + + +Q +
Sbjct: 94 EELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGREQEL 153
Query: 101 EEQRRQXXXXXXXNTRIS-EQINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQA 159
E+ RR+ R + E+ L + L Q E +AT++RL+
Sbjct: 154 EQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEATRLRLEKEALE 213
Query: 160 QAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQ 219
++ E QLA +L RE++ + L L+ TLT E L G Q I K
Sbjct: 214 GSLFEVQ-RQLA-QLEARREQLEAEGQAL----LLAKETLTGE-LAGLRQQIIATQEKAS 266
Query: 220 TVHVLLHNSLKPPEKPPERGGDEKQMALLN--QRISQLAENN-ISLKSEIERLKASVIRT 276
L+ L E+ + E++ A QR+ + E L++E +L++ + R
Sbjct: 267 LDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQRE 326
Query: 277 EESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQ 336
+E LA RL+ + E ++ L + RDE + +Q ++++ +T ++E
Sbjct: 327 QEELLA---RLEAEKEELSEEIAALQQERDEGLLLAESEKQQALSLKESEKTALSEKLMG 383
Query: 337 LAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQLRILGLQTQ------VQSLRRTA 390
S A +S E ER++ + + R T N ++LR L Q + Q +RR
Sbjct: 384 TRHSLATIS-LEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQREEAAAAHAQEVRRLQ 442
Query: 391 SSTGDGDGENQEC 403
D + C
Sbjct: 443 EQARDLGKQRDSC 455
Score = 40.3 bits (90), Expect = 0.012
Identities = 89/421 (21%), Positives = 168/421 (39%), Gaps = 49/421 (11%)
Query: 17 RCQHRETQNKL-RELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDEL 75
R H E +L RE E + L L ++ EQE L + E E +E+
Sbjct: 291 RAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQR--EQE---ELLARLEAEKEELSEEI 345
Query: 76 RTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEK 135
L +E+++ L + QA L E ++ I+LE++R K Q +
Sbjct: 346 AALQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSR 405
Query: 136 LQELAPIPDLLKATQMRLKDAQQAQAIAEH-----NAEQLAREL-----NCARE------ 179
++ + L +++R AQ+ +A A H ++ AR+L +C RE
Sbjct: 406 QEQDRSTVNAL-TSELRDLRAQREEAAAAHAQEVRRLQEQARDLGKQRDSCLREAEELRT 464
Query: 180 --KVVHIFRYLYSLYLVTTMTLTQEDLFGQS---------QSEIGRGNKDQTVHVLLHNS 228
+++ R L+ +E G+ + +G G K++ +
Sbjct: 465 QLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEE 524
Query: 229 LKPPEKPPERGGDEKQMALLN--QRISQLAENNISLKSEIERLKASVIRTEESALANEKR 286
L+ K E ++A + Q+++ L E ++ E L+ + E S L +
Sbjct: 525 LRSAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRE 584
Query: 287 LQEKMHECAQLGGELDRTRDEASR-----AL-QRAHEQTETVRKCLQTTVAELERQLAAS 340
LQE + L E R E + AL +RA +++ L+ + + E L
Sbjct: 585 LQELRRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVM 644
Query: 341 RAQVSTAEKEREELKNRLHWQMKRLTENFEQA------QL-RILGLQTQVQSLRRTASST 393
R ++ A+++ +E + + +RL + E+A QL GL+ ++++ R A+
Sbjct: 645 RQELQVAQRKLQEQEGEFRTRERRLLGSLEEARGTEKQQLDHARGLELKLEAARAEAAEL 704
Query: 394 G 394
G
Sbjct: 705 G 705
Score = 39.5 bits (88), Expect = 0.021
Identities = 88/395 (22%), Positives = 164/395 (41%), Gaps = 50/395 (12%)
Query: 21 RETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMK 80
R+ Q + E E E + L G + + QE +VR + RE R +D++ TL +
Sbjct: 857 RQLQKAVAESE---EARRSVDGRLSGVQAELALQEESVRRSE---RERRATLDQVATLER 910
Query: 81 EQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINL-EIQRVKLKFQEKLQEL 139
LQ + +Q+ + + + R+ E ++ E + VKL+ Q + E
Sbjct: 911 S----LQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLE- 965
Query: 140 APIPDLLKATQMRLKDAQ-QAQAIAEHNAEQLARELNCAREKV----VHIFRYLYSLYLV 194
L+ +++ L D + QAQA+ + + L R++ + K + + R +L V
Sbjct: 966 ----GELQRSRLGLSDREAQAQALQDR-VDSLQRQVADSEVKAGTLQLTVERLNGALAKV 1020
Query: 195 TTMTLTQED-------LFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMAL 247
D QS + + +D+ +H L +L E +R ++++
Sbjct: 1021 EESEGALRDKVRGLTEALAQSSASLN-STRDKNLH--LQKALTACEH--DRQVLQERLDA 1075
Query: 248 LNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLG-GE------ 300
Q +S+ + + SL +++ L+ V E + E +LQ+ Q GE
Sbjct: 1076 ARQALSEARKQSSSLGEQVQTLRGEVADLELQRVEAEGQLQQLREVLRQRQEGEAAALNT 1135
Query: 301 LDRTRDEASR------ALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKER--- 351
+ + +DE +LQRA Q E ++ ++ + LE+ A R + E+E+
Sbjct: 1136 VQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVEREKLRS 1195
Query: 352 EELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSL 386
E RL + RL A+L + Q Q+Q L
Sbjct: 1196 HEDTVRLSAEKGRLDRTLTGAELELAEAQRQIQQL 1230
Score = 39.5 bits (88), Expect = 0.021
Identities = 72/368 (19%), Positives = 139/368 (37%), Gaps = 18/368 (4%)
Query: 23 TQNKLRELEMKFEGLATHTNMLMGSKEQAFE----QEVNVRALKQCYREAREEIDELRTL 78
T+++LR + K + + L G K + E E L+ R E+ R
Sbjct: 915 TESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLG 974
Query: 79 MKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKL-- 136
+ ++ Q Q + + Q+ V + + R++ + +++ + ++K+
Sbjct: 975 LSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLTVERLNGAL-AKVEESEGALRDKVRG 1033
Query: 137 --QELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLV 194
+ LA L +T+ + Q+A EH+ + L L+ AR+ + + SL
Sbjct: 1034 LTEALAQSSASLNSTRDKNLHLQKALTACEHDRQVLQERLDAARQALSEARKQSSSLG-E 1092
Query: 195 TTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQ 254
TL E + Q G Q VL + + LL +R+
Sbjct: 1093 QVQTLRGEVADLELQRVEAEGQLQQLREVLRQRQEGEAAALNTVQKLQDERRLLQERLGS 1152
Query: 255 LAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQR 314
L L++E ++ S +R E+ +A + L + E +L D R A +
Sbjct: 1153 LQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVERE--KLRSHEDTVRLSAEKG--- 1207
Query: 315 AHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQL 374
+ + + +AE +RQ+ AQV E+ + + Q ++L E +L
Sbjct: 1208 ---RLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDAQQQQLELQQEVERL 1264
Query: 375 RILGLQTQ 382
R QT+
Sbjct: 1265 RSAQAQTE 1272
Score = 35.9 bits (79), Expect = 0.26
Identities = 33/119 (27%), Positives = 60/119 (50%), Gaps = 10/119 (8%)
Query: 248 LNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDE 307
LN+ ++QL E +L+ + + +E+ +A E+ QE++ E +L E+ R E
Sbjct: 58 LNRLVAQLEEEKSALQGRQRQAE------QEATVAREE--QERLEEL-RLEQEVARQGLE 108
Query: 308 AS-RALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRL 365
S R ++A E E L+ ++L+ QLA Q+S E+E E+ + Q++ L
Sbjct: 109 GSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARREAQRQVEAL 167
Score = 33.1 bits (72), Expect = 1.8
Identities = 31/135 (22%), Positives = 59/135 (43%), Gaps = 1/135 (0%)
Query: 246 ALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTR 305
A L +S+L+ N SL + L V + EE A + R ++ E E +R
Sbjct: 35 ASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQERL- 93
Query: 306 DEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRL 365
+E + A + E + + LE+QL R + S +++ +L +L + + L
Sbjct: 94 EELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGREQEL 153
Query: 366 TENFEQAQLRILGLQ 380
+ +AQ ++ L+
Sbjct: 154 EQARREAQRQVEALE 168
>BC031603-1|AAH31603.1| 422|Homo sapiens ALS2CR12 protein protein.
Length = 422
Score = 46.8 bits (106), Expect = 1e-04
Identities = 66/296 (22%), Positives = 127/296 (42%), Gaps = 20/296 (6%)
Query: 115 TRISEQINLEIQRV-KLKFQEKLQELAPIPDLLKATQMRLKDAQQAQ-AIAEHNAEQ-LA 171
T I EQ+N + Q KL E A + + LK+A +A+ + E+N + L
Sbjct: 138 TAIIEQMNRDHQSAQKLLSSEMDLRCAEMKQNFENKNRELKEAHEAELSELENNYKAALK 197
Query: 172 RELNCAREKVVHI---FRYLYSLYLVTTMTL--TQEDLFGQSQSEIGRGNKDQTVHVLLH 226
E A+EK+ + ++YL +++ ++ E+ + + +++ + K + ++LL
Sbjct: 198 AEKLAAQEKLEEMGKEYKYLKNMFRTYQDSIYDEMEEKWSKQKAKWKKDEKFERENILLQ 257
Query: 227 NSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKR 286
K +K G+E + +N+ S + EN I K E+ + S E ++
Sbjct: 258 QKKKMTKKFEMESGEEDKK--INESCSAVFENFIQEKEELLKQHQSDTLQLEELRKTKEV 315
Query: 287 LQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVST 346
+QE++H A + L+ LQ+ + K LQT AE E + + Q+ T
Sbjct: 316 MQEELHAQALILESLNTNLYYTQLELQKEKAIVGNLEKMLQTKFAETEEKYKHT-IQILT 374
Query: 347 AEKEREELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRRTASSTGDGDGENQE 402
E +H + K +++N E + G + + + + DG + QE
Sbjct: 375 EE--------NIHLKQKIISKNEEICE-GCSGRLASITVSKDDSDTVQDGSKKGQE 421
>Z20656-1|CAA79675.1| 1939|Homo sapiens cardiac alpha-myosin heavy
chain protein.
Length = 1939
Score = 46.4 bits (105), Expect = 2e-04
Identities = 63/312 (20%), Positives = 128/312 (41%), Gaps = 18/312 (5%)
Query: 61 LKQCYREAREEIDELRTLMKEQNDQLQDYRVKY----LQAQQLVEEQRRQXXXXXXXNTR 116
L++ Y E E EL+ ++ + N ++ +R KY +Q + +EE +++
Sbjct: 1345 LREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEE 1404
Query: 117 ISEQINLE---IQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQ--AQAIAE--HNAEQ 169
E +N + +++ K + Q ++++L + A L Q+ + +AE E+
Sbjct: 1405 AVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEE 1464
Query: 170 LARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSL 229
EL ++++ + L+ L +L + F + + D T L
Sbjct: 1465 SQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLT-EQLGEGGK 1523
Query: 230 KPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQE 289
E R E + L S L E SL+ E ++ + + + E++L E
Sbjct: 1524 NVHELEKVRKQLEVEKLELQ---SALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAE 1580
Query: 290 KMHECAQLGGELDRTRDEASRALQ---RAHEQTETVRKCLQTTVAELERQLAASRAQVST 346
K E Q R D +L R+ + V+K ++ + E+E QL+ + +
Sbjct: 1581 KDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAE 1640
Query: 347 AEKEREELKNRL 358
A+K+ + L++ L
Sbjct: 1641 AQKQVKSLQSLL 1652
Score = 39.9 bits (89), Expect = 0.016
Identities = 77/403 (19%), Positives = 169/403 (41%), Gaps = 50/403 (12%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTL 78
++ E+Q++L + + L+T L + E++ E ++ K+ + +EEI +L
Sbjct: 1461 KYEESQSELESSQKEARSLSTELFKLKNAYEESLE---HLETFKRENKNLQEEISDLTEQ 1517
Query: 79 MKEQNDQLQDYRV--KYLQAQQL-VEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEK 135
+ E + + K L+ ++L ++ + + LE ++K + + K
Sbjct: 1518 LGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERK 1577
Query: 136 LQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVT 195
L E + K R+ D+ Q AE + R +V+ + + +
Sbjct: 1578 LAEKDEEMEQAKRNHQRVVDSLQTSLDAETRS----------RNEVLRVKKKMEGDLNEM 1627
Query: 196 TMTLTQED-LFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQ 254
+ L+ + + ++Q ++ +++ LL ++ + D K+ + +R
Sbjct: 1628 EIQLSHANRMAAEAQKQV------KSLQSLLKDTQIQLDDAVRANDDLKENIAIVER--- 1678
Query: 255 LAENNISLKSEIERLKASVIRTEESALANEKRLQEK--------------MHECAQLGGE 300
NN+ L++E+E L+A V +TE S E+ L E +++ ++ +
Sbjct: 1679 --RNNL-LQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESD 1735
Query: 301 LDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHW 360
L + + E A+Q E +K + T A + +L + Q ++A ER +K +
Sbjct: 1736 LTQLQSEVEEAVQECRNAEEKAKKAI-TDAAMMAEEL--KKEQDTSAHLER--MKKNMEQ 1790
Query: 361 QMKRLTENFEQA-QLRILGLQTQVQSLR-RTASSTGDGDGENQ 401
+K L ++A Q+ + G + Q+Q L R G+ + E +
Sbjct: 1791 TIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGELEAEQK 1833
Score = 38.7 bits (86), Expect = 0.037
Identities = 32/159 (20%), Positives = 65/159 (40%), Gaps = 3/159 (1%)
Query: 237 ERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQ 296
E G +Q+ ISQL +S ++E LK + ++ A LQ H+C
Sbjct: 1285 ENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDL 1344
Query: 297 LGGELD---RTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREE 353
L + + + E R L +A+ + R +T + +L ++ +++ ++ EE
Sbjct: 1345 LREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEE 1404
Query: 354 LKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRRTASS 392
++ + L + + Q I L V+ A++
Sbjct: 1405 AVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAA 1443
Score = 36.7 bits (81), Expect = 0.15
Identities = 72/358 (20%), Positives = 143/358 (39%), Gaps = 20/358 (5%)
Query: 23 TQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQ 82
T+NK++ L + GL L +KE+ QE + +AL E ++++ L +
Sbjct: 973 TENKVKNLTEEMAGLDEIIAKL--TKEKKALQEAHQQALDDLQVE-EDKVNSLSKSKVKL 1029
Query: 83 NDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKL------ 136
Q+ D L+ ++ V + + +++++ ++++ KL+ +EKL
Sbjct: 1030 EQQVDDLEGS-LEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFD 1088
Query: 137 --QELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLV 194
Q+ + I D K ++ QA E E+L E AR KV + R S L
Sbjct: 1089 INQQNSKIEDEQALALQLQKKLKENQARIEELEEELEAE-RTARAKVEKL-RSDLSREL- 1145
Query: 195 TTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGD--EKQMALLNQRI 252
++ E+ G + +I K + + L+ E K+ A +
Sbjct: 1146 EEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAEL 1205
Query: 253 SQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRAL 312
+ +N +K ++E+ K+ + +N +++ + ++ L+ +E L
Sbjct: 1206 GEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKL 1265
Query: 313 QRAHEQTE---TVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTE 367
+ A T R LQT EL RQL A +S + + ++ ++L E
Sbjct: 1266 EEAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEE 1323
Score = 36.7 bits (81), Expect = 0.15
Identities = 57/284 (20%), Positives = 115/284 (40%), Gaps = 18/284 (6%)
Query: 120 QINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCARE 179
++ +++ E +++ + LLK TQ++L DA +A + N + R N +
Sbjct: 1626 EMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQA 1685
Query: 180 KVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERG 239
+ L L V T L Q I + Q +H + SL +K E
Sbjct: 1686 E-------LEELRAVVEQTERSRKL--AEQELIETSERVQLLH-SQNTSLINQKKKMESD 1735
Query: 240 GDEKQMALLNQRISQLAENNISLKSEI--ERLKASVIRTEESALANEKRLQEKMHECAQL 297
+ Q + + + + + K I + A ++ E+ A+ +R+++ M + +
Sbjct: 1736 LTQLQ-SEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIK- 1793
Query: 298 GGELDRTRDEASR-ALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKN 356
+L DEA + AL+ +Q + + ++ ELE + + V K +K
Sbjct: 1794 --DLQHRLDEAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIK- 1850
Query: 357 RLHWQMKRLTENFEQAQLRILGLQTQVQSLRRTASSTGDGDGEN 400
L +Q + +N + Q + LQ +V++ +R A + N
Sbjct: 1851 ELTYQTEEDKKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTN 1894
>BC132667-1|AAI32668.1| 1939|Homo sapiens myosin, heavy chain 6,
cardiac muscle, alpha (cardiomyopathy, hypertrophic 1)
protein.
Length = 1939
Score = 46.4 bits (105), Expect = 2e-04
Identities = 63/312 (20%), Positives = 128/312 (41%), Gaps = 18/312 (5%)
Query: 61 LKQCYREAREEIDELRTLMKEQNDQLQDYRVKY----LQAQQLVEEQRRQXXXXXXXNTR 116
L++ Y E E EL+ ++ + N ++ +R KY +Q + +EE +++
Sbjct: 1345 LREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEE 1404
Query: 117 ISEQINLE---IQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQ--AQAIAE--HNAEQ 169
E +N + +++ K + Q ++++L + A L Q+ + +AE E+
Sbjct: 1405 AVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEE 1464
Query: 170 LARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSL 229
EL ++++ + L+ L +L + F + + D T L
Sbjct: 1465 SQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLT-EQLGEGGK 1523
Query: 230 KPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQE 289
E R E + L S L E SL+ E ++ + + + E++L E
Sbjct: 1524 NVHELEKVRKQLEVEKLELQ---SALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAE 1580
Query: 290 KMHECAQLGGELDRTRDEASRALQ---RAHEQTETVRKCLQTTVAELERQLAASRAQVST 346
K E Q R D +L R+ + V+K ++ + E+E QL+ + +
Sbjct: 1581 KDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAE 1640
Query: 347 AEKEREELKNRL 358
A+K+ + L++ L
Sbjct: 1641 AQKQVKSLQSLL 1652
Score = 39.9 bits (89), Expect = 0.016
Identities = 77/403 (19%), Positives = 169/403 (41%), Gaps = 50/403 (12%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTL 78
++ E+Q++L + + L+T L + E++ E ++ K+ + +EEI +L
Sbjct: 1461 KYEESQSELESSQKEARSLSTELFKLKNAYEESLE---HLETFKRENKNLQEEISDLTEQ 1517
Query: 79 MKEQNDQLQDYRV--KYLQAQQL-VEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEK 135
+ E + + K L+ ++L ++ + + LE ++K + + K
Sbjct: 1518 LGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERK 1577
Query: 136 LQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVT 195
L E + K R+ D+ Q AE + R +V+ + + +
Sbjct: 1578 LAEKDEEMEQAKRNHQRVVDSLQTSLDAETRS----------RNEVLRVKKKMEGDLNEM 1627
Query: 196 TMTLTQED-LFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQ 254
+ L+ + + ++Q ++ +++ LL ++ + D K+ + +R
Sbjct: 1628 EIQLSHANRMAAEAQKQV------KSLQSLLKDTQIQLDDAVRANDDLKENIAIVER--- 1678
Query: 255 LAENNISLKSEIERLKASVIRTEESALANEKRLQEK--------------MHECAQLGGE 300
NN+ L++E+E L+A V +TE S E+ L E +++ ++ +
Sbjct: 1679 --RNNL-LQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESD 1735
Query: 301 LDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHW 360
L + + E A+Q E +K + T A + +L + Q ++A ER +K +
Sbjct: 1736 LTQLQSEVEEAVQECRNAEEKAKKAI-TDAAMMAEEL--KKEQDTSAHLER--MKKNMEQ 1790
Query: 361 QMKRLTENFEQA-QLRILGLQTQVQSLR-RTASSTGDGDGENQ 401
+K L ++A Q+ + G + Q+Q L R G+ + E +
Sbjct: 1791 TIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGELEAEQK 1833
Score = 38.7 bits (86), Expect = 0.037
Identities = 32/159 (20%), Positives = 65/159 (40%), Gaps = 3/159 (1%)
Query: 237 ERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQ 296
E G +Q+ ISQL +S ++E LK + ++ A LQ H+C
Sbjct: 1285 ENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDL 1344
Query: 297 LGGELD---RTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREE 353
L + + + E R L +A+ + R +T + +L ++ +++ ++ EE
Sbjct: 1345 LREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEE 1404
Query: 354 LKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRRTASS 392
++ + L + + Q I L V+ A++
Sbjct: 1405 AVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAA 1443
Score = 36.7 bits (81), Expect = 0.15
Identities = 57/284 (20%), Positives = 115/284 (40%), Gaps = 18/284 (6%)
Query: 120 QINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCARE 179
++ +++ E +++ + LLK TQ++L DA +A + N + R N +
Sbjct: 1626 EMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQA 1685
Query: 180 KVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERG 239
+ L L V T L Q I + Q +H + SL +K E
Sbjct: 1686 E-------LEELRAVVEQTERSRKL--AEQELIETSERVQLLH-SQNTSLINQKKKMESD 1735
Query: 240 GDEKQMALLNQRISQLAENNISLKSEI--ERLKASVIRTEESALANEKRLQEKMHECAQL 297
+ Q + + + + + K I + A ++ E+ A+ +R+++ M + +
Sbjct: 1736 LTQLQ-SEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIK- 1793
Query: 298 GGELDRTRDEASR-ALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKN 356
+L DEA + AL+ +Q + + ++ ELE + + V K +K
Sbjct: 1794 --DLQHRLDEAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIK- 1850
Query: 357 RLHWQMKRLTENFEQAQLRILGLQTQVQSLRRTASSTGDGDGEN 400
L +Q + +N + Q + LQ +V++ +R A + N
Sbjct: 1851 ELTYQTEEDKKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTN 1894
Score = 36.3 bits (80), Expect = 0.20
Identities = 72/358 (20%), Positives = 143/358 (39%), Gaps = 20/358 (5%)
Query: 23 TQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQ 82
T+NK++ L + GL L +KE+ QE + +AL E ++++ L +
Sbjct: 973 TENKVKNLTEEMAGLDEIIAKL--TKEKKALQEAHQQALDDLQVE-EDKVNSLSKSKVKL 1029
Query: 83 NDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKL------ 136
Q+ D L+ ++ V + + +++++ ++++ KL+ +EKL
Sbjct: 1030 EQQVDDLEGS-LEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFD 1088
Query: 137 --QELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLV 194
Q+ + I D K ++ QA E E+L E AR KV + R S L
Sbjct: 1089 INQQNSKIEDEQVLALQLQKKLKENQARIEELEEELEAE-RTARAKVEKL-RSDLSREL- 1145
Query: 195 TTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGD--EKQMALLNQRI 252
++ E+ G + +I K + + L+ E K+ A +
Sbjct: 1146 EEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAEL 1205
Query: 253 SQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRAL 312
+ +N +K ++E+ K+ + +N +++ + ++ L+ +E L
Sbjct: 1206 GEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKL 1265
Query: 313 QRAHEQTE---TVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTE 367
+ A T R LQT EL RQL A +S + + ++ ++L E
Sbjct: 1266 EEAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEE 1323
>BC114620-1|AAI14621.1| 1756|Homo sapiens periplakin protein.
Length = 1756
Score = 46.4 bits (105), Expect = 2e-04
Identities = 79/364 (21%), Positives = 155/364 (42%), Gaps = 32/364 (8%)
Query: 22 ETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKE 81
E + K R E + + L Q +EV +K Y+ E EL+ L +E
Sbjct: 1197 EQERKYRGAEEQLRSYQSELEALRRRGPQVEVKEVTKEVIK--YKTDPEMEKELQRLREE 1254
Query: 82 QNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQ---E 138
D+ + L+ QL +E + +T+ Q +Q + L+FQE Q E
Sbjct: 1255 IVDKTRLIERCDLEIYQLKKEIQ------ALKDTKPQVQTKEVVQEI-LQFQEDPQTKEE 1307
Query: 139 LAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVH--IFRYLYSLYLVTT 196
+A + L Q + D ++ +A E + EL+ +E+VV + RY L
Sbjct: 1308 VASLRAKLSEEQKKQVDLERERASQEEQIARKEEELSRVKERVVQQEVVRYEEEPGLRAE 1367
Query: 197 MTLTQEDL------FGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPE-RGGDEKQMALLN 249
+ E + + ++E+ R + +T L L+ E+ + R E+++ L
Sbjct: 1368 ASAFAESIDVELRQIDKLRAELRRLQRRRTE---LERQLEELERERQARREAEREVQRLQ 1424
Query: 250 QRISQLAENNISLKSEIERLKASVIRTE-----ESALANEKRLQEKMHECAQLGGELDRT 304
QR++ L + + ++ + V++ + E AL +L+E+ H L GEL+
Sbjct: 1425 QRLAALEQEEAEAREKVTHTQKVVLQQDPQQAREHALLR-LQLEEEQHRRQLLEGELETL 1483
Query: 305 RDEASRALQRAHEQTETV-RKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMK 363
R + + AL++A + + V + +Q + E+++ ++ + + + EL +
Sbjct: 1484 RRKLA-ALEKAEVKEKVVLSESVQVEKGDTEQEIQRLKSSLEEESRSKRELDVEVSRLEA 1542
Query: 364 RLTE 367
RL+E
Sbjct: 1543 RLSE 1546
Score = 35.9 bits (79), Expect = 0.26
Identities = 31/115 (26%), Positives = 49/115 (42%), Gaps = 2/115 (1%)
Query: 17 RCQHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELR 76
R + R Q + ELE + E L ++ + + + AL+Q EARE++ +
Sbjct: 1386 RAELRRLQRRRTELERQLEELERERQARREAEREVQRLQQRLAALEQEEAEAREKVTHTQ 1445
Query: 77 TLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLK 131
++ +Q+ Q R L QL EEQ R+ T + LE VK K
Sbjct: 1446 KVVLQQDP--QQAREHALLRLQLEEEQHRRQLLEGELETLRRKLAALEKAEVKEK 1498
Score = 34.7 bits (76), Expect = 0.60
Identities = 33/142 (23%), Positives = 66/142 (46%), Gaps = 17/142 (11%)
Query: 237 ERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQ 296
++G E ++ LL QR++ LAE + ++ + ++ + A ++LQE Q
Sbjct: 1023 QKGAREAEVLLLQQRVAALAEEKSRAQEKVTEKEVVKLQNDPQLEAEYQQLQEDHQRQDQ 1082
Query: 297 L----GGELDRTRDEASRALQRAHEQTE---TVRKCL--------QTTVAELERQLAASR 341
L EL +D+ R L++ E TV++ L + V++L RQ
Sbjct: 1083 LREKQEEELSFLQDKLKR-LEKERAMAEGKITVKEVLKVEKDAATEREVSDLTRQYEDEA 1141
Query: 342 AQVSTAEKEREELKNRLHWQMK 363
A+ +++E+ EL ++ W ++
Sbjct: 1142 AKARASQREKTELLRKI-WALE 1162
>BC023021-1|AAH23021.1| 731|Homo sapiens golgi autoantigen, golgin
subfamily a, 5 protein.
Length = 731
Score = 46.4 bits (105), Expect = 2e-04
Identities = 75/345 (21%), Positives = 138/345 (40%), Gaps = 34/345 (9%)
Query: 66 REAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRI----SEQI 121
R R ++D+L + ++ QL +V+ +A QL+ + +RI SE
Sbjct: 281 RGLRAQVDDLTEAVAAKDSQLAVLKVRLQEADQLLSTRTEALEALQSEKSRIMQDQSEGN 340
Query: 122 NLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAI----AEHNAEQLARELNCA 177
+L+ Q ++ QE+L E LK Q K Q A E + LA + A
Sbjct: 341 SLQNQALQT-LQERLHEADAT---LKREQESYKQMQSEFAARLNKVEMERQNLAEAITLA 396
Query: 178 REKV------VHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLH----- 226
K V + LY + + QE + + ++ +K++ ++ L
Sbjct: 397 ERKYSDEKKRVDELQQQVKLYKLNLESSKQELIDYKQKATRILQSKEKLINSLKEGSGFE 456
Query: 227 --NSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANE 284
+S E EK+M + I +L L+SE++ ++A + ESA
Sbjct: 457 GLDSSTASSMELEELRHEKEMQ--REEIQKLMGQIHQLRSELQDMEAQQVNEAESAREQL 514
Query: 285 KRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQV 344
+ L +++ EL+ + + E + LQ+ + + + ++ R Q+
Sbjct: 515 QDLHDQIAGQKASKQELETELERLKQEFHYIEEDLYRTKNTLQSRIKDRDEEIQKLRNQL 574
Query: 345 ST---AEKEREELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSL 386
+ + + EL+NRLH +LTE Q Q + L T+ SL
Sbjct: 575 TNKTLSNSSQSELENRLH----QLTETLIQKQTMLESLSTEKNSL 615
Score = 33.5 bits (73), Expect = 1.4
Identities = 32/134 (23%), Positives = 57/134 (42%), Gaps = 15/134 (11%)
Query: 25 NKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQND 84
N L+E FEGL + T M +E E+E+ REEI +L + +
Sbjct: 447 NSLKE-GSGFEGLDSSTASSMELEELRHEKEMQ-----------REEIQKLMGQIHQLRS 494
Query: 85 QLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPD 144
+LQD + + + EQ + +++ E++R+K +F ++L +
Sbjct: 495 ELQDMEAQQVNEAESAREQLQDLHDQIAGQKASKQELETELERLKQEFHYIEEDLYRTKN 554
Query: 145 LLKATQMRLKDAQQ 158
L Q R+KD +
Sbjct: 555 TL---QSRIKDRDE 565
>AY644768-1|AAV85456.1| 731|Homo sapiens cell
proliferation-inducing gene 31 protein.
Length = 731
Score = 46.4 bits (105), Expect = 2e-04
Identities = 75/345 (21%), Positives = 138/345 (40%), Gaps = 34/345 (9%)
Query: 66 REAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRI----SEQI 121
R R ++D+L + ++ QL +V+ +A QL+ + +RI SE
Sbjct: 281 RGLRAQVDDLTEAVAAKDSQLAVLKVRLQEADQLLSTRTEALEALQSEKSRIMQDQSEGN 340
Query: 122 NLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAI----AEHNAEQLARELNCA 177
+L+ Q ++ QE+L E LK Q K Q A E + LA + A
Sbjct: 341 SLQNQALQT-LQERLHEADAT---LKREQESYKQMQSEFAARLNKVEMERQNLAEAITLA 396
Query: 178 REKV------VHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLH----- 226
K V + LY + + QE + + ++ +K++ ++ L
Sbjct: 397 ERKYSDEKKRVDELQQQVKLYKLNLESSKQELIDYKQKATRILQSKEKLINSLKEGSGFE 456
Query: 227 --NSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANE 284
+S E EK+M + I +L L+SE++ ++A + ESA
Sbjct: 457 GLDSSTASSMELEELRHEKEMQ--REEIQKLMGQIHQLRSELQDMEAQQVNEAESAREQL 514
Query: 285 KRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQV 344
+ L +++ EL+ + + E + LQ+ + + + ++ R Q+
Sbjct: 515 QDLHDQIAGQKASKQELETELERLKQEFHYIEEDLYRTKNTLQSRIKDRDEEIQKLRNQL 574
Query: 345 ST---AEKEREELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSL 386
+ + + EL+NRLH +LTE Q Q + L T+ SL
Sbjct: 575 TNKTLSNSSQSELENRLH----QLTETLIQKQTMLESLSTEKNSL 615
Score = 33.5 bits (73), Expect = 1.4
Identities = 32/134 (23%), Positives = 57/134 (42%), Gaps = 15/134 (11%)
Query: 25 NKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQND 84
N L+E FEGL + T M +E E+E+ REEI +L + +
Sbjct: 447 NSLKE-GSGFEGLDSSTASSMELEELRHEKEMQ-----------REEIQKLMGQIHQLRS 494
Query: 85 QLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPD 144
+LQD + + + EQ + +++ E++R+K +F ++L +
Sbjct: 495 ELQDMEAQQVNEAESAREQLQDLHDQIAGQKASKQELETELERLKQEFHYIEEDLYRTKN 554
Query: 145 LLKATQMRLKDAQQ 158
L Q R+KD +
Sbjct: 555 TL---QSRIKDRDE 565
>AF085199-1|AAD09753.1| 731|Homo sapiens golgin-84 protein.
Length = 731
Score = 46.4 bits (105), Expect = 2e-04
Identities = 75/345 (21%), Positives = 138/345 (40%), Gaps = 34/345 (9%)
Query: 66 REAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRI----SEQI 121
R R ++D+L + ++ QL +V+ +A QL+ + +RI SE
Sbjct: 281 RGLRAQVDDLTEAVAAKDSQLAVLKVRLQEADQLLSTRTEALEALQSEKSRIMQDQSEGN 340
Query: 122 NLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAI----AEHNAEQLARELNCA 177
+L+ Q ++ QE+L E LK Q K Q A E + LA + A
Sbjct: 341 SLQNQALQT-LQERLHEADAT---LKREQESYKQMQSEFAARLNKVEMERQNLAEAITLA 396
Query: 178 REKV------VHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLH----- 226
K V + LY + + QE + + ++ +K++ ++ L
Sbjct: 397 ERKYSDEKKRVDELQQQVKLYKLNLESSKQELIDYKQKATRILQSKEKLINSLKEGSGFE 456
Query: 227 --NSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANE 284
+S E EK+M + I +L L+SE++ ++A + ESA
Sbjct: 457 GLDSSTASSMELEELRHEKEMQ--REEIQKLMGQIHQLRSELQDMEAQQVNEAESAREQL 514
Query: 285 KRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQV 344
+ L +++ EL+ + + E + LQ+ + + + ++ R Q+
Sbjct: 515 QDLHDQIAGQKASKQELETELERLKQEFHYIEEDLYRTKNTLQSRIKDRDEEIQKLRNQL 574
Query: 345 ST---AEKEREELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSL 386
+ + + EL+NRLH +LTE Q Q + L T+ SL
Sbjct: 575 TNKTLSNSSQSELENRLH----QLTETLIQKQTMLESLSTEKNSL 615
Score = 33.5 bits (73), Expect = 1.4
Identities = 32/134 (23%), Positives = 57/134 (42%), Gaps = 15/134 (11%)
Query: 25 NKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQND 84
N L+E FEGL + T M +E E+E+ REEI +L + +
Sbjct: 447 NSLKE-GSGFEGLDSSTASSMELEELRHEKEMQ-----------REEIQKLMGQIHQLRS 494
Query: 85 QLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPD 144
+LQD + + + EQ + +++ E++R+K +F ++L +
Sbjct: 495 ELQDMEAQQVNEAESAREQLQDLHDQIAGQKASKQELETELERLKQEFHYIEEDLYRTKN 554
Query: 145 LLKATQMRLKDAQQ 158
L Q R+KD +
Sbjct: 555 TL---QSRIKDRDE 565
>AF041004-1|AAD17459.1| 1756|Homo sapiens periplakin protein.
Length = 1756
Score = 46.4 bits (105), Expect = 2e-04
Identities = 79/364 (21%), Positives = 155/364 (42%), Gaps = 32/364 (8%)
Query: 22 ETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKE 81
E + K R E + + L Q +EV +K Y+ E EL+ L +E
Sbjct: 1197 EQERKYRGAEEQLRSYQSELEALRRRGPQVEVKEVTKEVIK--YKTDPEMEKELQRLREE 1254
Query: 82 QNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQ---E 138
D+ + L+ QL +E + +T+ Q +Q + L+FQE Q E
Sbjct: 1255 IVDKTRLIERCDLEIYQLKKEIQ------ALKDTKPQVQTKEVVQEI-LQFQEDPQTKEE 1307
Query: 139 LAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVH--IFRYLYSLYLVTT 196
+A + L Q + D ++ +A E + EL+ +E+VV + RY L
Sbjct: 1308 VASLRAKLSEEQKKQVDLERERASQEEQIARKEEELSRVKERVVQQEVVRYEEEPGLRAE 1367
Query: 197 MTLTQEDL------FGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPE-RGGDEKQMALLN 249
+ E + + ++E+ R + +T L L+ E+ + R E+++ L
Sbjct: 1368 ASAFAESIDVELRQIDKLRAELRRLQRRRTE---LERQLEELERERQARREAEREVQRLQ 1424
Query: 250 QRISQLAENNISLKSEIERLKASVIRTE-----ESALANEKRLQEKMHECAQLGGELDRT 304
QR++ L + + ++ + V++ + E AL +L+E+ H L GEL+
Sbjct: 1425 QRLAALEQEEAEAREKVTHTQKVVLQQDPQQAREHALLR-LQLEEEQHRRQLLEGELETL 1483
Query: 305 RDEASRALQRAHEQTETV-RKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMK 363
R + + AL++A + + V + +Q + E+++ ++ + + + EL +
Sbjct: 1484 RRKLA-ALEKAEVKEKVVLSESVQVEKGDTEQEIQRLKSSLEEESRSKRELDVEVSRLEA 1542
Query: 364 RLTE 367
RL+E
Sbjct: 1543 RLSE 1546
Score = 35.9 bits (79), Expect = 0.26
Identities = 31/115 (26%), Positives = 49/115 (42%), Gaps = 2/115 (1%)
Query: 17 RCQHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELR 76
R + R Q + ELE + E L ++ + + + AL+Q EARE++ +
Sbjct: 1386 RAELRRLQRRRTELERQLEELERERQARREAEREVQRLQQRLAALEQEEAEAREKVTHTQ 1445
Query: 77 TLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLK 131
++ +Q+ Q R L QL EEQ R+ T + LE VK K
Sbjct: 1446 KVVLQQDP--QQAREHALLRLQLEEEQHRRQLLEGELETLRRKLAALEKAEVKEK 1498
Score = 34.7 bits (76), Expect = 0.60
Identities = 33/142 (23%), Positives = 66/142 (46%), Gaps = 17/142 (11%)
Query: 237 ERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQ 296
++G E ++ LL QR++ LAE + ++ + ++ + A ++LQE Q
Sbjct: 1023 QKGAREAEVLLLQQRVAALAEEKSRAQEKVTEKEVVKLQNDPQLEAEYQQLQEDHQRQDQ 1082
Query: 297 L----GGELDRTRDEASRALQRAHEQTE---TVRKCL--------QTTVAELERQLAASR 341
L EL +D+ R L++ E TV++ L + V++L RQ
Sbjct: 1083 LREKQEEELSFLQDKLKR-LEKERAMAEGKITVKEVLKVEKDAATEREVSDLTRQYEDEA 1141
Query: 342 AQVSTAEKEREELKNRLHWQMK 363
A+ +++E+ EL ++ W ++
Sbjct: 1142 AKARASQREKTELLRKI-WALE 1162
>AF013717-1|AAC39668.1| 1756|Homo sapiens periplakin protein.
Length = 1756
Score = 46.4 bits (105), Expect = 2e-04
Identities = 79/364 (21%), Positives = 155/364 (42%), Gaps = 32/364 (8%)
Query: 22 ETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKE 81
E + K R E + + L Q +EV +K Y+ E EL+ L +E
Sbjct: 1197 EQERKYRGAEEQLRSYQSELEALRRRGPQVEVKEVTKEVIK--YKTDPEMEKELQRLREE 1254
Query: 82 QNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQ---E 138
D+ + L+ QL +E + +T+ Q +Q + L+FQE Q E
Sbjct: 1255 IVDKTRLIERCDLEIYQLKKEIQ------ALKDTKPQVQTKEVVQEI-LQFQEDPQTKEE 1307
Query: 139 LAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVH--IFRYLYSLYLVTT 196
+A + L Q + D ++ +A E + EL+ +E+VV + RY L
Sbjct: 1308 VASLRAKLSEEQKKQVDLERERASQEEQIARKEEELSRVKERVVQQEVVRYEEEPGLRAE 1367
Query: 197 MTLTQEDL------FGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPE-RGGDEKQMALLN 249
+ E + + ++E+ R + +T L L+ E+ + R E+++ L
Sbjct: 1368 ASAFAESIDVELRQIDKLRAELRRLQRRRTE---LERQLEELERERQARREAEREVQRLQ 1424
Query: 250 QRISQLAENNISLKSEIERLKASVIRTE-----ESALANEKRLQEKMHECAQLGGELDRT 304
QR++ L + + ++ + V++ + E AL +L+E+ H L GEL+
Sbjct: 1425 QRLAALEQEEAEAREKVTHTQKVVLQQDPQQAREHALLR-LQLEEEQHRRQLLEGELETL 1483
Query: 305 RDEASRALQRAHEQTETV-RKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMK 363
R + + AL++A + + V + +Q + E+++ ++ + + + EL +
Sbjct: 1484 RRKLA-ALEKAEVKEKVVLSESVQVEKGDTEQEIQRLKSSLEEESRSKRELDVEVSRLEA 1542
Query: 364 RLTE 367
RL+E
Sbjct: 1543 RLSE 1546
Score = 35.9 bits (79), Expect = 0.26
Identities = 31/115 (26%), Positives = 49/115 (42%), Gaps = 2/115 (1%)
Query: 17 RCQHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELR 76
R + R Q + ELE + E L ++ + + + AL+Q EARE++ +
Sbjct: 1386 RAELRRLQRRRTELERQLEELERERQARREAEREVQRLQQRLAALEQEEAEAREKVTHTQ 1445
Query: 77 TLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLK 131
++ +Q+ Q R L QL EEQ R+ T + LE VK K
Sbjct: 1446 KVVLQQDP--QQAREHALLRLQLEEEQHRRQLLEGELETLRRKLAALEKAEVKEK 1498
Score = 34.7 bits (76), Expect = 0.60
Identities = 33/142 (23%), Positives = 66/142 (46%), Gaps = 17/142 (11%)
Query: 237 ERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQ 296
++G E ++ LL QR++ LAE + ++ + ++ + A ++LQE Q
Sbjct: 1023 QKGAREAEVLLLQQRVAALAEEKSRAQEKVTEKEVVKLQNDPQLEAEYQQLQEDHQRQDQ 1082
Query: 297 L----GGELDRTRDEASRALQRAHEQTE---TVRKCL--------QTTVAELERQLAASR 341
L EL +D+ R L++ E TV++ L + V++L RQ
Sbjct: 1083 LREKQEEELSFLQDKLKR-LEKERAMAEGKITVKEVLKVEKDAATEREVSDLTRQYEDEA 1141
Query: 342 AQVSTAEKEREELKNRLHWQMK 363
A+ +++E+ EL ++ W ++
Sbjct: 1142 AKARASQREKTELLRKI-WALE 1162
>AF001691-1|AAC17738.1| 1756|Homo sapiens 195 kDa cornified envelope
precursor protein.
Length = 1756
Score = 46.4 bits (105), Expect = 2e-04
Identities = 79/364 (21%), Positives = 155/364 (42%), Gaps = 32/364 (8%)
Query: 22 ETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKE 81
E + K R E + + L Q +EV +K Y+ E EL+ L +E
Sbjct: 1197 EQERKYRGAEEQLRSYQSELEALRRRGPQVEVKEVTKEVIK--YKTDPEMEKELQRLREE 1254
Query: 82 QNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQ---E 138
D+ + L+ QL +E + +T+ Q +Q + L+FQE Q E
Sbjct: 1255 IVDKTRLIERCDLEIYQLKKEIQ------ALKDTKPQVQTKEVVQEI-LQFQEDPQTKEE 1307
Query: 139 LAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVH--IFRYLYSLYLVTT 196
+A + L Q + D ++ +A E + EL+ +E+VV + RY L
Sbjct: 1308 VASLRAKLSEEQKKQVDLERERASQEEQIARKEEELSRVKERVVQQEVVRYEEEPGLRAE 1367
Query: 197 MTLTQEDL------FGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPE-RGGDEKQMALLN 249
+ E + + ++E+ R + +T L L+ E+ + R E+++ L
Sbjct: 1368 ASAFAESIDVELRQIDKLRAELRRLQRRRTE---LERQLEELERERQARREAEREVQRLQ 1424
Query: 250 QRISQLAENNISLKSEIERLKASVIRTE-----ESALANEKRLQEKMHECAQLGGELDRT 304
QR++ L + + ++ + V++ + E AL +L+E+ H L GEL+
Sbjct: 1425 QRLAALEQEEAEAREKVTHTQKVVLQQDPQQAREHALLR-LQLEEEQHRRQLLEGELETL 1483
Query: 305 RDEASRALQRAHEQTETV-RKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMK 363
R + + AL++A + + V + +Q + E+++ ++ + + + EL +
Sbjct: 1484 RRKLA-ALEKAEVKEKVVLSESVQVEKGDTEQEIQRLKSSLEEESRSKRELDVEVSRLEA 1542
Query: 364 RLTE 367
RL+E
Sbjct: 1543 RLSE 1546
Score = 35.9 bits (79), Expect = 0.26
Identities = 31/115 (26%), Positives = 49/115 (42%), Gaps = 2/115 (1%)
Query: 17 RCQHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELR 76
R + R Q + ELE + E L ++ + + + AL+Q EARE++ +
Sbjct: 1386 RAELRRLQRRRTELERQLEELERERQARREAEREVQRLQQRLAALEQEEAEAREKVTHTQ 1445
Query: 77 TLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLK 131
++ +Q+ Q R L QL EEQ R+ T + LE VK K
Sbjct: 1446 KVVLQQDP--QQAREHALLRLQLEEEQHRRQLLEGELETLRRKLAALEKAEVKEK 1498
Score = 34.7 bits (76), Expect = 0.60
Identities = 33/142 (23%), Positives = 66/142 (46%), Gaps = 17/142 (11%)
Query: 237 ERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQ 296
++G E ++ LL QR++ LAE + ++ + ++ + A ++LQE Q
Sbjct: 1023 QKGAREAEVLLLQQRVAALAEEKSRAQEKVTEKEVVKLQNDPQLEAEYQQLQEDHQRQDQ 1082
Query: 297 L----GGELDRTRDEASRALQRAHEQTE---TVRKCL--------QTTVAELERQLAASR 341
L EL +D+ R L++ E TV++ L + V++L RQ
Sbjct: 1083 LREKQEEELSFLQDKLKR-LEKERAMAEGKITVKEVLKVEKDAATEREVSDLTRQYEDEA 1141
Query: 342 AQVSTAEKEREELKNRLHWQMK 363
A+ +++E+ EL ++ W ++
Sbjct: 1142 AKARASQREKTELLRKI-WALE 1162
>AB011140-1|BAA25494.1| 1426|Homo sapiens KIAA0568 protein protein.
Length = 1426
Score = 46.4 bits (105), Expect = 2e-04
Identities = 79/364 (21%), Positives = 155/364 (42%), Gaps = 32/364 (8%)
Query: 22 ETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKE 81
E + K R E + + L Q +EV +K Y+ E EL+ L +E
Sbjct: 867 EQERKYRGAEEQLRSYQSELEALRRRGPQVEVKEVTKEVIK--YKTDPEMEKELQRLREE 924
Query: 82 QNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQ---E 138
D+ + L+ QL +E + +T+ Q +Q + L+FQE Q E
Sbjct: 925 IVDKTRLIERCDLEIYQLKKEIQ------ALKDTKPQVQTKEVVQEI-LQFQEDPQTKEE 977
Query: 139 LAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVH--IFRYLYSLYLVTT 196
+A + L Q + D ++ +A E + EL+ +E+VV + RY L
Sbjct: 978 VASLRAKLSEEQKKQVDLERERASQEEQIARKEEELSRVKERVVQQEVVRYEEEPGLRAE 1037
Query: 197 MTLTQEDL------FGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPE-RGGDEKQMALLN 249
+ E + + ++E+ R + +T L L+ E+ + R E+++ L
Sbjct: 1038 ASAFAESIDVELRQIDKLRAELRRLQRRRTE---LERQLEELERERQARREAEREVQRLQ 1094
Query: 250 QRISQLAENNISLKSEIERLKASVIRTE-----ESALANEKRLQEKMHECAQLGGELDRT 304
QR++ L + + ++ + V++ + E AL +L+E+ H L GEL+
Sbjct: 1095 QRLAALEQEEAEAREKVTHTQKVVLQQDPQQAREHALLR-LQLEEEQHRRQLLEGELETL 1153
Query: 305 RDEASRALQRAHEQTETV-RKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMK 363
R + + AL++A + + V + +Q + E+++ ++ + + + EL +
Sbjct: 1154 RRKLA-ALEKAEVKEKVVLSESVQVEKGDTEQEIQRLKSSLEEESRSKRELDVEVSRLEA 1212
Query: 364 RLTE 367
RL+E
Sbjct: 1213 RLSE 1216
Score = 35.9 bits (79), Expect = 0.26
Identities = 31/115 (26%), Positives = 49/115 (42%), Gaps = 2/115 (1%)
Query: 17 RCQHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELR 76
R + R Q + ELE + E L ++ + + + AL+Q EARE++ +
Sbjct: 1056 RAELRRLQRRRTELERQLEELERERQARREAEREVQRLQQRLAALEQEEAEAREKVTHTQ 1115
Query: 77 TLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLK 131
++ +Q+ Q R L QL EEQ R+ T + LE VK K
Sbjct: 1116 KVVLQQDP--QQAREHALLRLQLEEEQHRRQLLEGELETLRRKLAALEKAEVKEK 1168
Score = 34.7 bits (76), Expect = 0.60
Identities = 33/142 (23%), Positives = 66/142 (46%), Gaps = 17/142 (11%)
Query: 237 ERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQ 296
++G E ++ LL QR++ LAE + ++ + ++ + A ++LQE Q
Sbjct: 693 QKGAREAEVLLLQQRVAALAEEKSRAQEKVTEKEVVKLQNDPQLEAEYQQLQEDHQRQDQ 752
Query: 297 L----GGELDRTRDEASRALQRAHEQTE---TVRKCL--------QTTVAELERQLAASR 341
L EL +D+ R L++ E TV++ L + V++L RQ
Sbjct: 753 LREKQEEELSFLQDKLKR-LEKERAMAEGKITVKEVLKVEKDAATEREVSDLTRQYEDEA 811
Query: 342 AQVSTAEKEREELKNRLHWQMK 363
A+ +++E+ EL ++ W ++
Sbjct: 812 AKARASQREKTELLRKI-WALE 832
>M77830-1|AAA85135.1| 2871|Homo sapiens desmoplakin I protein.
Length = 2871
Score = 46.0 bits (104), Expect = 2e-04
Identities = 75/373 (20%), Positives = 159/373 (42%), Gaps = 38/373 (10%)
Query: 24 QNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQN 83
QN L+EL+++ + + N L K A E + L+ EE++ +R +KEQ
Sbjct: 1560 QNSLKELQLQKQKVEEELNRL---KRTASEDSCKRKKLE-------EELEGMRRSLKEQA 1609
Query: 84 DQLQDYRVKYLQA---QQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELA 140
++ + + QA ++ E+ RQ + R ++ E++R+ + + ++L
Sbjct: 1610 IKITNLTQQLEQASIVKKRSEDDLRQQRDVLDGHLREKQRTQEELRRLSSEVEALRRQLL 1669
Query: 141 PIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLT 200
+ +K +R + Q+A E +R LN E + I R L SL T LT
Sbjct: 1670 QEQESVKQAHLRNEHFQKA-------IEDKSRSLN---ESKIEIER-LQSL----TENLT 1714
Query: 201 QEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNI 260
+E L + + R D + S +K Q+ + N R +L
Sbjct: 1715 KEHLMLEEELRNLRLEYDD---LRRGRSEADSDKNATILELRSQLQISNNRTLELQGLIN 1771
Query: 261 SLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELD------RTRDEASRALQR 314
L+ E E L+ + + ++ AL R+QE ++C Q+ E + + ++ LQR
Sbjct: 1772 DLQRERENLRQEIEKFQKQALEASNRIQESKNQCTQVVQERESLLVKIKVLEQDKARLQR 1831
Query: 315 AHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQL 374
++ + L+ ++++L + Q+ + + +R ++++ E+++
Sbjct: 1832 LEDELNRAKSTLEAE-TRVKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIESEREKSER 1890
Query: 375 RILGLQTQVQSLR 387
L+++++ L+
Sbjct: 1891 EKNSLRSEIERLQ 1903
Score = 44.4 bits (100), Expect = 7e-04
Identities = 79/411 (19%), Positives = 171/411 (41%), Gaps = 44/411 (10%)
Query: 21 RETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNV--RALKQCYREAREEIDELRT- 77
+E + RE E + + H N M + +E E+N+ +K+ + ++ LR
Sbjct: 1179 QEEGTRKREYENELAKVRNHYNEEMSNLRNKYETEINITKTTIKEISMQKEDDSKNLRNQ 1238
Query: 78 --LMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEK 135
+ +N L+D V+ + EQRR+ +I + Q ++++ ++
Sbjct: 1239 LDRLSRENRDLKDEIVRLNDSILQATEQRRRAEENALQQKACGSEIMQKKQHLEIELKQV 1298
Query: 136 LQELA--------PIPDLLKATQMRLKDAQQAQAIAEHNAE-------QLARELNCAREK 180
+Q+ + + + K Q + K+ ++ +A + A+ +L++ N E+
Sbjct: 1299 MQQRSEDNARHKQSLEEAAKTIQDKNKEIERLKAEFQEEAKRRWEYENELSKVRNNYDEE 1358
Query: 181 VVHIFRYLYSLYLVTTMTLTQ------EDLFG-QSQ-SEIGRGNKDQTVHV-LLHNSLKP 231
++ + + +T T+ Q ED G ++Q + R N+ + + L N+L
Sbjct: 1359 IISLKNQFETEINITKTTIHQLTMQKEEDTSGYRAQIDNLTRENRSLSEEIKRLKNTLTQ 1418
Query: 232 PEKPPER-GGDEKQMALLNQRISQLAEN-NISLKSEIERLKASVIRTEESALANEKRLQE 289
+ R D +Q +SQ + + L+ + +R ++S K +Q+
Sbjct: 1419 TTENLRRVEEDIQQQKATGSEVSQRKQQLEVELRQVTQMRTEESVRYKQSLDDAAKTIQD 1478
Query: 290 KMHECAQLGGELDR-TRD-----EASRALQRAHEQTETVRKCLQTTVAEL---ERQLAAS 340
K E +L +D+ T D + + LQR + T+ +L E++L
Sbjct: 1479 KNKEIERLKQLIDKETNDRKCLEDENARLQRVQYDLQKANSSATETINKLKVQEQELTRL 1538
Query: 341 RAQVSTAEKEREELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRRTAS 391
R +ER +K++ + R + ++ QL+ ++ ++ L+RTAS
Sbjct: 1539 RIDYERVSQER-TVKDQ---DITRFQNSLKELQLQKQKVEEELNRLKRTAS 1585
Score = 37.1 bits (82), Expect = 0.11
Identities = 58/318 (18%), Positives = 127/318 (39%), Gaps = 23/318 (7%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTL 78
+ + TQ +LR L + E L L+ +E + + ++ + ++E +
Sbjct: 1646 EKQRTQEELRRLSSEVEALR---RQLLQEQESVKQAHLRNEHFQKAIEDKSRSLNESKIE 1702
Query: 79 MKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQE 138
++ ++ ++L ++ + R + + N I ++ + Q
Sbjct: 1703 IERLQSLTENLTKEHLMLEEELRNLRLEYDDLRRGRSEADSDKNATILELRSQLQISNNR 1762
Query: 139 LAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMT 198
+ L+ Q ++ +Q + A + + + ++ + + + SL LV
Sbjct: 1763 TLELQGLINDLQRERENLRQEIEKFQKQALEASNRIQESKNQCTQVVQERESL-LVKIKV 1821
Query: 199 LTQEDLFGQS-QSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDE-------KQMALL-- 248
L Q+ Q + E+ R + L+ ++ + ++ K+ A+
Sbjct: 1822 LEQDKARLQRLEDELNRAKSTLEAETRVKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKI 1881
Query: 249 -NQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHEC-AQLGGELDRTRD 306
++R E N SL+SEIERL+A + R EE ++L++ E +QL E R +
Sbjct: 1882 ESEREKSEREKN-SLRSEIERLQAEIKRIEERC---RRKLEDSTRETQSQLETERSRYQR 1937
Query: 307 EASRALQR---AHEQTET 321
E + QR +H +T+T
Sbjct: 1938 EIDKLRQRPYGSHRETQT 1955
Score = 35.9 bits (79), Expect = 0.26
Identities = 79/400 (19%), Positives = 160/400 (40%), Gaps = 33/400 (8%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTL 78
Q + T +++ + + + E + + ++Q ++ A + ++ +EI+ L+ L
Sbjct: 1432 QQKATGSEVSQRKQQLEVELRQVTQMRTEESVRYKQSLDDAA--KTIQDKNKEIERLKQL 1489
Query: 79 M-KEQNDQ--LQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQ----INLEIQRVKLK 131
+ KE ND+ L+D + LQ Q ++ ++ EQ + ++ +RV +
Sbjct: 1490 IDKETNDRKCLEDENAR-LQRVQYDLQKANSSATETINKLKVQEQELTRLRIDYERVSQE 1548
Query: 132 FQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQ-------LARELNCAR----EK 180
K Q++ + LK Q++ + ++ + A + L EL R E+
Sbjct: 1549 RTVKDQDITRFQNSLKELQLQKQKVEEELNRLKRTASEDSCKRKKLEEELEGMRRSLKEQ 1608
Query: 181 VVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEI-GRGNKDQTVHVLLHNSLKPPEKPPERG 239
+ I L + + ED Q + + G + Q L E +
Sbjct: 1609 AIKITNLTQQLEQASIVKKRSEDDLRQQRDVLDGHLREKQRTQEELRRLSSEVEALRRQL 1668
Query: 240 GDE----KQMALLNQRISQLAENNI-SL---KSEIERLKASVIRTEESALANEKRLQEKM 291
E KQ L N+ + E+ SL K EIERL++ + L E+ L+
Sbjct: 1669 LQEQESVKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLR 1728
Query: 292 HECAQLG-GELDRTRDEASRALQ-RAHEQTETVRKC-LQTTVAELERQLAASRAQVSTAE 348
E L G + D+ + L+ R+ Q R LQ + +L+R+ R ++ +
Sbjct: 1729 LEYDDLRRGRSEADSDKNATILELRSQLQISNNRTLELQGLINDLQRERENLRQEIEKFQ 1788
Query: 349 KEREELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRR 388
K+ E NR+ + T+ ++ + ++ ++ Q R
Sbjct: 1789 KQALEASNRIQESKNQCTQVVQERESLLVKIKVLEQDKAR 1828
Score = 33.5 bits (73), Expect = 1.4
Identities = 67/340 (19%), Positives = 135/340 (39%), Gaps = 27/340 (7%)
Query: 66 REAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEI 125
R E+I + + E + + Q V+ Q Q+ E+ + + + N EI
Sbjct: 1424 RRVEEDIQQQKATGSEVSQRKQQLEVELRQVTQMRTEESVRYKQSLDDAAKTIQDKNKEI 1483
Query: 126 QRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIF 185
+R+K ++ + + D Q D Q+A + A +L +E+ +
Sbjct: 1484 ERLKQLIDKETNDRKCLEDENARLQRVQYDLQKANSSATETINKLK-----VQEQELTRL 1538
Query: 186 RYLYSLYLVTTMTLTQEDL--FGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEK 243
R Y + T+ +D+ F S E+ + K + L E +R E+
Sbjct: 1539 RIDYE-RVSQERTVKDQDITRFQNSLKEL-QLQKQKVEEELNRLKRTASEDSCKRKKLEE 1596
Query: 244 QMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDR 303
++ + + + + A +L ++E +AS+++ ++ R Q + L G L R
Sbjct: 1597 ELEGMRRSLKEQAIKITNLTQQLE--QASIVKKRSE---DDLRQQRDV-----LDGHL-R 1645
Query: 304 TRDEASRALQRAHEQTETVRK-CLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQ- 361
+ L+R + E +R+ LQ + + L Q + +K R ++++ +
Sbjct: 1646 EKQRTQEELRRLSSEVEALRRQLLQEQESVKQAHLRNEHFQKAIEDKSRSLNESKIEIER 1705
Query: 362 MKRLTENFEQAQL----RILGLQTQVQSLRRTASSTGDGD 397
++ LTEN + L + L+ + LRR S D D
Sbjct: 1706 LQSLTENLTKEHLMLEEELRNLRLEYDDLRR-GRSEADSD 1744
>J05211-1|AAA35766.1| 1752|Homo sapiens protein ( Human desmoplakin
mRNA, 3' end. ).
Length = 1752
Score = 46.0 bits (104), Expect = 2e-04
Identities = 75/373 (20%), Positives = 159/373 (42%), Gaps = 38/373 (10%)
Query: 24 QNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQN 83
QN L+EL+++ + + N L K A E + L+ EE++ +R +KEQ
Sbjct: 441 QNSLKELQLQKQKVEEELNRL---KRTASEDSCKRKKLE-------EELEGMRRSLKEQA 490
Query: 84 DQLQDYRVKYLQA---QQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELA 140
++ + + QA ++ E+ RQ + R ++ E++R+ + + ++L
Sbjct: 491 IKITNLTQQLEQASIVKKRSEDDLRQQRDVLDGHLREKQRTQEELRRLSSEVEALRRQLL 550
Query: 141 PIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLT 200
+ +K +R + Q+A E +R LN E + I R L SL T LT
Sbjct: 551 QEQESVKQAHLRNEHFQKA-------IEDKSRSLN---ESKIEIER-LQSL----TENLT 595
Query: 201 QEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNI 260
+E L + + R D + S +K Q+ + N R +L
Sbjct: 596 KEHLMLEEELRNLRLEYDD---LRRGRSEADSDKNATILELRSQLQISNNRTLELQGLIN 652
Query: 261 SLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELD------RTRDEASRALQR 314
L+ E E L+ + + ++ AL R+QE ++C Q+ E + + ++ LQR
Sbjct: 653 DLQRERENLRQEIEKFQKQALEASNRIQESKNQCTQVVQERESLLVKIKVLEQDKARLQR 712
Query: 315 AHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQL 374
++ + L+ ++++L + Q+ + + +R ++++ E+++
Sbjct: 713 LEDELNRAKSTLEAE-TRVKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIESEREKSER 771
Query: 375 RILGLQTQVQSLR 387
L+++++ L+
Sbjct: 772 EKNSLRSEIERLQ 784
Score = 44.4 bits (100), Expect = 7e-04
Identities = 79/411 (19%), Positives = 171/411 (41%), Gaps = 44/411 (10%)
Query: 21 RETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNV--RALKQCYREAREEIDELRT- 77
+E + RE E + + H N M + +E E+N+ +K+ + ++ LR
Sbjct: 60 QEEGTRKREYENELAKVRNHYNEEMSNLRNKYETEINITKTTIKEISMQKEDDSKNLRNQ 119
Query: 78 --LMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEK 135
+ +N L+D V+ + EQRR+ +I + Q ++++ ++
Sbjct: 120 LDRLSRENRDLKDEIVRLNDSILQATEQRRRAEENALQQKACGSEIMQKKQHLEIELKQV 179
Query: 136 LQELA--------PIPDLLKATQMRLKDAQQAQAIAEHNAE-------QLARELNCAREK 180
+Q+ + + + K Q + K+ ++ +A + A+ +L++ N E+
Sbjct: 180 MQQRSEDNARHKQSLEEAAKTIQDKNKEIERLKAEFQEEAKRRWEYENELSKVRNNYDEE 239
Query: 181 VVHIFRYLYSLYLVTTMTLTQ------EDLFG-QSQ-SEIGRGNKDQTVHV-LLHNSLKP 231
++ + + +T T+ Q ED G ++Q + R N+ + + L N+L
Sbjct: 240 IISLKNQFETEINITKTTIHQLTMQKEEDTSGYRAQIDNLTRENRSLSEEIKRLKNTLTQ 299
Query: 232 PEKPPER-GGDEKQMALLNQRISQLAEN-NISLKSEIERLKASVIRTEESALANEKRLQE 289
+ R D +Q +SQ + + L+ + +R ++S K +Q+
Sbjct: 300 TTENLRRVEEDIQQQKATGSEVSQRKQQLEVELRQVTQMRTEESVRYKQSLDDAAKTIQD 359
Query: 290 KMHECAQLGGELDR-TRD-----EASRALQRAHEQTETVRKCLQTTVAEL---ERQLAAS 340
K E +L +D+ T D + + LQR + T+ +L E++L
Sbjct: 360 KNKEIERLKQLIDKETNDRKCLEDENARLQRVQYDLQKANSSATETINKLKVQEQELTRL 419
Query: 341 RAQVSTAEKEREELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRRTAS 391
R +ER +K++ + R + ++ QL+ ++ ++ L+RTAS
Sbjct: 420 RIDYERVSQER-TVKDQ---DITRFQNSLKELQLQKQKVEEELNRLKRTAS 466
Score = 37.1 bits (82), Expect = 0.11
Identities = 58/318 (18%), Positives = 127/318 (39%), Gaps = 23/318 (7%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTL 78
+ + TQ +LR L + E L L+ +E + + ++ + ++E +
Sbjct: 527 EKQRTQEELRRLSSEVEALR---RQLLQEQESVKQAHLRNEHFQKAIEDKSRSLNESKIE 583
Query: 79 MKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQE 138
++ ++ ++L ++ + R + + N I ++ + Q
Sbjct: 584 IERLQSLTENLTKEHLMLEEELRNLRLEYDDLRRGRSEADSDKNATILELRSQLQISNNR 643
Query: 139 LAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMT 198
+ L+ Q ++ +Q + A + + + ++ + + + SL LV
Sbjct: 644 TLELQGLINDLQRERENLRQEIEKFQKQALEASNRIQESKNQCTQVVQERESL-LVKIKV 702
Query: 199 LTQEDLFGQS-QSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDE-------KQMALL-- 248
L Q+ Q + E+ R + L+ ++ + ++ K+ A+
Sbjct: 703 LEQDKARLQRLEDELNRAKSTLEAETRVKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKI 762
Query: 249 -NQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHEC-AQLGGELDRTRD 306
++R E N SL+SEIERL+A + R EE ++L++ E +QL E R +
Sbjct: 763 ESEREKSEREKN-SLRSEIERLQAEIKRIEERC---RRKLEDSTRETQSQLETERSRYQR 818
Query: 307 EASRALQR---AHEQTET 321
E + QR +H +T+T
Sbjct: 819 EIDKLRQRPYGSHRETQT 836
Score = 35.9 bits (79), Expect = 0.26
Identities = 79/400 (19%), Positives = 160/400 (40%), Gaps = 33/400 (8%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTL 78
Q + T +++ + + + E + + ++Q ++ A + ++ +EI+ L+ L
Sbjct: 313 QQKATGSEVSQRKQQLEVELRQVTQMRTEESVRYKQSLDDAA--KTIQDKNKEIERLKQL 370
Query: 79 M-KEQNDQ--LQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQ----INLEIQRVKLK 131
+ KE ND+ L+D + LQ Q ++ ++ EQ + ++ +RV +
Sbjct: 371 IDKETNDRKCLEDENAR-LQRVQYDLQKANSSATETINKLKVQEQELTRLRIDYERVSQE 429
Query: 132 FQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQ-------LARELNCAR----EK 180
K Q++ + LK Q++ + ++ + A + L EL R E+
Sbjct: 430 RTVKDQDITRFQNSLKELQLQKQKVEEELNRLKRTASEDSCKRKKLEEELEGMRRSLKEQ 489
Query: 181 VVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEI-GRGNKDQTVHVLLHNSLKPPEKPPERG 239
+ I L + + ED Q + + G + Q L E +
Sbjct: 490 AIKITNLTQQLEQASIVKKRSEDDLRQQRDVLDGHLREKQRTQEELRRLSSEVEALRRQL 549
Query: 240 GDE----KQMALLNQRISQLAENNI-SL---KSEIERLKASVIRTEESALANEKRLQEKM 291
E KQ L N+ + E+ SL K EIERL++ + L E+ L+
Sbjct: 550 LQEQESVKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLR 609
Query: 292 HECAQLG-GELDRTRDEASRALQ-RAHEQTETVRKC-LQTTVAELERQLAASRAQVSTAE 348
E L G + D+ + L+ R+ Q R LQ + +L+R+ R ++ +
Sbjct: 610 LEYDDLRRGRSEADSDKNATILELRSQLQISNNRTLELQGLINDLQRERENLRQEIEKFQ 669
Query: 349 KEREELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRR 388
K+ E NR+ + T+ ++ + ++ ++ Q R
Sbjct: 670 KQALEASNRIQESKNQCTQVVQERESLLVKIKVLEQDKAR 709
Score = 33.5 bits (73), Expect = 1.4
Identities = 67/340 (19%), Positives = 135/340 (39%), Gaps = 27/340 (7%)
Query: 66 REAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEI 125
R E+I + + E + + Q V+ Q Q+ E+ + + + N EI
Sbjct: 305 RRVEEDIQQQKATGSEVSQRKQQLEVELRQVTQMRTEESVRYKQSLDDAAKTIQDKNKEI 364
Query: 126 QRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIF 185
+R+K ++ + + D Q D Q+A + A +L +E+ +
Sbjct: 365 ERLKQLIDKETNDRKCLEDENARLQRVQYDLQKANSSATETINKLK-----VQEQELTRL 419
Query: 186 RYLYSLYLVTTMTLTQEDL--FGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEK 243
R Y + T+ +D+ F S E+ + K + L E +R E+
Sbjct: 420 RIDYE-RVSQERTVKDQDITRFQNSLKEL-QLQKQKVEEELNRLKRTASEDSCKRKKLEE 477
Query: 244 QMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDR 303
++ + + + + A +L ++E +AS+++ ++ R Q + L G L R
Sbjct: 478 ELEGMRRSLKEQAIKITNLTQQLE--QASIVKKRSE---DDLRQQRDV-----LDGHL-R 526
Query: 304 TRDEASRALQRAHEQTETVRK-CLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQ- 361
+ L+R + E +R+ LQ + + L Q + +K R ++++ +
Sbjct: 527 EKQRTQEELRRLSSEVEALRRQLLQEQESVKQAHLRNEHFQKAIEDKSRSLNESKIEIER 586
Query: 362 MKRLTENFEQAQL----RILGLQTQVQSLRRTASSTGDGD 397
++ LTEN + L + L+ + LRR S D D
Sbjct: 587 LQSLTENLTKEHLMLEEELRNLRLEYDDLRR-GRSEADSD 625
>BX530088-1|CAI95784.1| 810|Homo sapiens GRIP1 associated protein 1
protein.
Length = 810
Score = 46.0 bits (104), Expect = 2e-04
Identities = 79/404 (19%), Positives = 169/404 (41%), Gaps = 31/404 (7%)
Query: 26 KLRELEMKFEGLATHTNMLMGSKEQAFEQ-----EVNVRALKQCYREAREEIDELRTLMK 80
KL++ + F L T L E+ E + +A ++ ++E++ +
Sbjct: 234 KLKKKQESFCRLQTEKETLFNDSRNKIEELQQRKEADHKAQLARTQKLQQELEAANQSLA 293
Query: 81 EQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINL--EIQRVKLKFQEKLQE 138
E DQ Q R+++ A + +++Q Q N + L E+Q+ + ++++ + +
Sbjct: 294 ELRDQRQGERLEHAAALRALQDQI-QTAKTQELNMLREQTTGLAAELQQQQAEYEDLMGQ 352
Query: 139 LAPI-PDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTM 197
+ L ++ + + +Q Q I + EQL +EL AR+ L L + T
Sbjct: 353 KDDLNSQLQESLRANSRLLEQLQEIGQEK-EQLTQELQEARKSAEKRKAMLDELAMETLQ 411
Query: 198 TLTQ--EDL----FGQSQSEIG-RGNKDQTVHVLLHNSLKPPEKPPERGGDEK----QMA 246
+Q E+L + +G R ++ + L + + E+ + +EK ++
Sbjct: 412 EKSQHKEELGAVRLRHEKEVLGVRARYERELRELHEDKKRQEEELRGQIREEKARTRELE 471
Query: 247 LLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRD 306
L Q + +L S+ + + EES ++ +E + +C + + ++
Sbjct: 472 TLQQTVEELQAQVHSMDGAKGWFERRLKEAEESLQQQQQEQEEALKQCREQHAAELKGKE 531
Query: 307 EASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKE----REELKNRLHWQM 362
E + ++ EQ + R C T++ L++++ + EK+ ++LK +LH +
Sbjct: 532 EELQDVRDQLEQAQEERDCHLKTISSLKQEVKDTVDGQRILEKKGSAALKDLKRQLHLER 591
Query: 363 KRLTENFEQAQLRIL------GLQTQVQSLRRTASSTGDGDGEN 400
KR + E+ Q + GL+ V S + S T GD +
Sbjct: 592 KRADKLQERLQDILTNSKSRSGLEELVLSEMNSPSRTQTGDSSS 635
>AL031058-1|CAA19927.1| 2871|Homo sapiens desmoplakin protein.
Length = 2871
Score = 46.0 bits (104), Expect = 2e-04
Identities = 75/373 (20%), Positives = 159/373 (42%), Gaps = 38/373 (10%)
Query: 24 QNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQN 83
QN L+EL+++ + + N L K A E + L+ EE++ +R +KEQ
Sbjct: 1560 QNSLKELQLQKQKVEEELNRL---KRTASEDSCKRKKLE-------EELEGMRRSLKEQA 1609
Query: 84 DQLQDYRVKYLQA---QQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELA 140
++ + + QA ++ E+ RQ + R ++ E++R+ + + ++L
Sbjct: 1610 IKITNLTQQLEQASIVKKRSEDDLRQQRDVLDGHLREKQRTQEELRRLSSEVEALRRQLL 1669
Query: 141 PIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLT 200
+ +K +R + Q+A E +R LN E + I R L SL T LT
Sbjct: 1670 QEQESVKQAHLRNEHFQKA-------IEDKSRSLN---ESKIEIER-LQSL----TENLT 1714
Query: 201 QEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNI 260
+E L + + R D + S +K Q+ + N R +L
Sbjct: 1715 KEHLMLEEELRNLRLEYDD---LRRGRSEADSDKNATILELRSQLQISNNRTLELQGLIN 1771
Query: 261 SLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELD------RTRDEASRALQR 314
L+ E E L+ + + ++ AL R+QE ++C Q+ E + + ++ LQR
Sbjct: 1772 DLQRERENLRQEIEKFQKQALEASNRIQESKNQCTQVVQERESLLVKIKVLEQDKARLQR 1831
Query: 315 AHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQL 374
++ + L+ ++++L + Q+ + + +R ++++ E+++
Sbjct: 1832 LEDELNRAKSTLEAE-TRVKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIESEREKSER 1890
Query: 375 RILGLQTQVQSLR 387
L+++++ L+
Sbjct: 1891 EKNSLRSEIERLQ 1903
Score = 44.4 bits (100), Expect = 7e-04
Identities = 79/411 (19%), Positives = 171/411 (41%), Gaps = 44/411 (10%)
Query: 21 RETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNV--RALKQCYREAREEIDELRT- 77
+E + RE E + + H N M + +E E+N+ +K+ + ++ LR
Sbjct: 1179 QEEGTRKREYENELAKVRNHYNEEMSNLRNKYETEINITKTTIKEISMQKEDDSKNLRNQ 1238
Query: 78 --LMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEK 135
+ +N L+D V+ + EQRR+ +I + Q ++++ ++
Sbjct: 1239 LDRLSRENRDLKDEIVRLNDSILQATEQRRRAEENALQQKACGSEIMQKKQHLEIELKQV 1298
Query: 136 LQELA--------PIPDLLKATQMRLKDAQQAQAIAEHNAE-------QLARELNCAREK 180
+Q+ + + + K Q + K+ ++ +A + A+ +L++ N E+
Sbjct: 1299 MQQRSEDNARHKQSLEEAAKTIQDKNKEIERLKAEFQEEAKRRWEYENELSKVRNNYDEE 1358
Query: 181 VVHIFRYLYSLYLVTTMTLTQ------EDLFG-QSQ-SEIGRGNKDQTVHV-LLHNSLKP 231
++ + + +T T+ Q ED G ++Q + R N+ + + L N+L
Sbjct: 1359 IISLKNQFETEINITKTTIHQLTMQKEEDTSGYRAQIDNLTRENRSLSEEIKRLKNTLTQ 1418
Query: 232 PEKPPER-GGDEKQMALLNQRISQLAEN-NISLKSEIERLKASVIRTEESALANEKRLQE 289
+ R D +Q +SQ + + L+ + +R ++S K +Q+
Sbjct: 1419 TTENLRRVEEDIQQQKATGSEVSQRKQQLEVELRQVTQMRTEESVRYKQSLDDAAKTIQD 1478
Query: 290 KMHECAQLGGELDR-TRD-----EASRALQRAHEQTETVRKCLQTTVAEL---ERQLAAS 340
K E +L +D+ T D + + LQR + T+ +L E++L
Sbjct: 1479 KNKEIERLKQLIDKETNDRKCLEDENARLQRVQYDLQKANSSATETINKLKVQEQELTRL 1538
Query: 341 RAQVSTAEKEREELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRRTAS 391
R +ER +K++ + R + ++ QL+ ++ ++ L+RTAS
Sbjct: 1539 RIDYERVSQER-TVKDQ---DITRFQNSLKELQLQKQKVEEELNRLKRTAS 1585
Score = 37.1 bits (82), Expect = 0.11
Identities = 58/318 (18%), Positives = 127/318 (39%), Gaps = 23/318 (7%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTL 78
+ + TQ +LR L + E L L+ +E + + ++ + ++E +
Sbjct: 1646 EKQRTQEELRRLSSEVEALR---RQLLQEQESVKQAHLRNEHFQKAIEDKSRSLNESKIE 1702
Query: 79 MKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQE 138
++ ++ ++L ++ + R + + N I ++ + Q
Sbjct: 1703 IERLQSLTENLTKEHLMLEEELRNLRLEYDDLRRGRSEADSDKNATILELRSQLQISNNR 1762
Query: 139 LAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMT 198
+ L+ Q ++ +Q + A + + + ++ + + + SL LV
Sbjct: 1763 TLELQGLINDLQRERENLRQEIEKFQKQALEASNRIQESKNQCTQVVQERESL-LVKIKV 1821
Query: 199 LTQEDLFGQS-QSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDE-------KQMALL-- 248
L Q+ Q + E+ R + L+ ++ + ++ K+ A+
Sbjct: 1822 LEQDKARLQRLEDELNRAKSTLEAETRVKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKI 1881
Query: 249 -NQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHEC-AQLGGELDRTRD 306
++R E N SL+SEIERL+A + R EE ++L++ E +QL E R +
Sbjct: 1882 ESEREKSEREKN-SLRSEIERLQAEIKRIEERC---RRKLEDSTRETQSQLETERSRYQR 1937
Query: 307 EASRALQR---AHEQTET 321
E + QR +H +T+T
Sbjct: 1938 EIDKLRQRPYGSHRETQT 1955
Score = 35.9 bits (79), Expect = 0.26
Identities = 79/400 (19%), Positives = 160/400 (40%), Gaps = 33/400 (8%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTL 78
Q + T +++ + + + E + + ++Q ++ A + ++ +EI+ L+ L
Sbjct: 1432 QQKATGSEVSQRKQQLEVELRQVTQMRTEESVRYKQSLDDAA--KTIQDKNKEIERLKQL 1489
Query: 79 M-KEQNDQ--LQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQ----INLEIQRVKLK 131
+ KE ND+ L+D + LQ Q ++ ++ EQ + ++ +RV +
Sbjct: 1490 IDKETNDRKCLEDENAR-LQRVQYDLQKANSSATETINKLKVQEQELTRLRIDYERVSQE 1548
Query: 132 FQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQ-------LARELNCAR----EK 180
K Q++ + LK Q++ + ++ + A + L EL R E+
Sbjct: 1549 RTVKDQDITRFQNSLKELQLQKQKVEEELNRLKRTASEDSCKRKKLEEELEGMRRSLKEQ 1608
Query: 181 VVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEI-GRGNKDQTVHVLLHNSLKPPEKPPERG 239
+ I L + + ED Q + + G + Q L E +
Sbjct: 1609 AIKITNLTQQLEQASIVKKRSEDDLRQQRDVLDGHLREKQRTQEELRRLSSEVEALRRQL 1668
Query: 240 GDE----KQMALLNQRISQLAENNI-SL---KSEIERLKASVIRTEESALANEKRLQEKM 291
E KQ L N+ + E+ SL K EIERL++ + L E+ L+
Sbjct: 1669 LQEQESVKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLR 1728
Query: 292 HECAQLG-GELDRTRDEASRALQ-RAHEQTETVRKC-LQTTVAELERQLAASRAQVSTAE 348
E L G + D+ + L+ R+ Q R LQ + +L+R+ R ++ +
Sbjct: 1729 LEYDDLRRGRSEADSDKNATILELRSQLQISNNRTLELQGLINDLQRERENLRQEIEKFQ 1788
Query: 349 KEREELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRR 388
K+ E NR+ + T+ ++ + ++ ++ Q R
Sbjct: 1789 KQALEASNRIQESKNQCTQVVQERESLLVKIKVLEQDKAR 1828
Score = 33.5 bits (73), Expect = 1.4
Identities = 67/340 (19%), Positives = 135/340 (39%), Gaps = 27/340 (7%)
Query: 66 REAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEI 125
R E+I + + E + + Q V+ Q Q+ E+ + + + N EI
Sbjct: 1424 RRVEEDIQQQKATGSEVSQRKQQLEVELRQVTQMRTEESVRYKQSLDDAAKTIQDKNKEI 1483
Query: 126 QRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIF 185
+R+K ++ + + D Q D Q+A + A +L +E+ +
Sbjct: 1484 ERLKQLIDKETNDRKCLEDENARLQRVQYDLQKANSSATETINKLK-----VQEQELTRL 1538
Query: 186 RYLYSLYLVTTMTLTQEDL--FGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEK 243
R Y + T+ +D+ F S E+ + K + L E +R E+
Sbjct: 1539 RIDYE-RVSQERTVKDQDITRFQNSLKEL-QLQKQKVEEELNRLKRTASEDSCKRKKLEE 1596
Query: 244 QMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDR 303
++ + + + + A +L ++E +AS+++ ++ R Q + L G L R
Sbjct: 1597 ELEGMRRSLKEQAIKITNLTQQLE--QASIVKKRSE---DDLRQQRDV-----LDGHL-R 1645
Query: 304 TRDEASRALQRAHEQTETVRK-CLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQ- 361
+ L+R + E +R+ LQ + + L Q + +K R ++++ +
Sbjct: 1646 EKQRTQEELRRLSSEVEALRRQLLQEQESVKQAHLRNEHFQKAIEDKSRSLNESKIEIER 1705
Query: 362 MKRLTENFEQAQL----RILGLQTQVQSLRRTASSTGDGD 397
++ LTEN + L + L+ + LRR S D D
Sbjct: 1706 LQSLTENLTKEHLMLEEELRNLRLEYDDLRR-GRSEADSD 1744
>X52889-1|CAA37068.1| 1934|Homo sapiens cardiac beta myosin heavy
chain protein.
Length = 1934
Score = 45.6 bits (103), Expect = 3e-04
Identities = 62/313 (19%), Positives = 132/313 (42%), Gaps = 20/313 (6%)
Query: 61 LKQCYREAREEIDELRTLMKEQNDQLQDYRVKY----LQAQQLVEEQRRQXXXXXXXNTR 116
L++ Y E E EL+ ++ + N ++ +R KY +Q + +EE +++
Sbjct: 1343 LREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEE 1402
Query: 117 ISEQINLE---IQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQ--AQAIAE--HNAEQ 169
E +N + +++ K + Q ++++L + A L Q+ + +AE E+
Sbjct: 1403 AVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEE 1462
Query: 170 LARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHV-LLHNS 228
EL ++++ + L+ L +L + F + + D T + +
Sbjct: 1463 SQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKT 1522
Query: 229 LKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQ 288
+ EK ++ EK + S L E SL+ E ++ + + + E++L
Sbjct: 1523 IHELEKVRKQLEAEKM-----ELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLA 1577
Query: 289 EKMHECAQLGGELDRTRDEASRALQ---RAHEQTETVRKCLQTTVAELERQLAASRAQVS 345
EK E Q R D +L R+ + V+K ++ + E+E QL+ + +
Sbjct: 1578 EKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAA 1637
Query: 346 TAEKEREELKNRL 358
A+K+ + L++ L
Sbjct: 1638 EAQKQVKSLQSLL 1650
Score = 39.9 bits (89), Expect = 0.016
Identities = 55/339 (16%), Positives = 136/339 (40%), Gaps = 13/339 (3%)
Query: 67 EAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQ 126
+ ++++ EL+ ++E ++L+ R + ++L + R+ + +I+
Sbjct: 1103 QLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSCQIE 1162
Query: 127 RVKLK---FQEKLQEL--APIPDLLKATQMRLKDAQQAQAIAEH--NAEQLARELNCARE 179
K + FQ+ ++L A + A +R K A + E N +++ ++L +
Sbjct: 1163 MNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKS 1222
Query: 180 KV-VHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIG--RGNKDQTVHVLLHNSLKPPEKPP 236
+ + + ++ + E + + ++ R ++T + + + +
Sbjct: 1223 EFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQT 1282
Query: 237 ERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQ 296
E G +Q+ ISQL ++ ++E LK + ++ A LQ H+C
Sbjct: 1283 ENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDL 1342
Query: 297 LGGELD---RTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREE 353
L + + + E R L +A+ + R +T + +L ++ +++ +E EE
Sbjct: 1343 LREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEE 1402
Query: 354 LKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRRTASS 392
++ + L + + Q I L V+ A++
Sbjct: 1403 AVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAA 1441
Score = 31.9 bits (69), Expect = 4.3
Identities = 66/322 (20%), Positives = 127/322 (39%), Gaps = 23/322 (7%)
Query: 48 KEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQX 107
KE + E + L++ +E ++L+ ++ + D L D + QL++ + +
Sbjct: 860 KEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEER---CDQLIKNKIQLE 916
Query: 108 XXXXXXNTRIS--EQINLEIQRVKLKFQEKLQELA-PIPDL----------LKATQMRLK 154
N R+ E++N E+ K +++ EL I DL AT+ ++K
Sbjct: 917 AKVKEMNERLEDEEEMNAELTAKKRNVEDECSELKRDIDDLELTLAKVEKEKHATENKVK 976
Query: 155 DAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLY-LVTTMTLTQEDLFGQSQSEIG 213
+ + A + +L +E +E L + V T+T + L Q G
Sbjct: 977 NLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEG 1036
Query: 214 RGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASV 273
+++ V + L + + E + E M L N + QL E E+ L A +
Sbjct: 1037 SLEQEKKVRMDLERAKRKLEGDLKLT-QESIMDLENDK-QQLDERLKKKDFELNALNARI 1094
Query: 274 IRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAEL 333
+E AL ++ LQ+K+ E EL+ + A + + + + L+ L
Sbjct: 1095 --EDEQALGSQ--LQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERL 1150
Query: 334 ERQLAASRAQVSTAEKEREELK 355
E A+ Q+ +K E +
Sbjct: 1151 EEAGGATSCQIEMNKKREAEFQ 1172
>X51591-1|CAA35940.1| 1151|Homo sapiens beta-myosin heavy chain
(1151 AA) protein.
Length = 1151
Score = 45.6 bits (103), Expect = 3e-04
Identities = 60/312 (19%), Positives = 130/312 (41%), Gaps = 18/312 (5%)
Query: 61 LKQCYREAREEIDELRTLMKEQNDQLQDYRVKY----LQAQQLVEEQRRQXXXXXXXNTR 116
L++ Y E E EL+ ++ + N ++ +R KY +Q + +EE +++
Sbjct: 559 LREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEE 618
Query: 117 ISEQINLE---IQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQA--QAIAE--HNAEQ 169
E +N + +++ K + Q ++++L + A L Q+ + +AE E+
Sbjct: 619 AVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEE 678
Query: 170 LARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSL 229
EL ++++ + L+ L +L + F + + D T +
Sbjct: 679 SQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKT 738
Query: 230 KPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQE 289
+ + + ++M L S L E SL+ E ++ + + + E++L E
Sbjct: 739 IHELEKVRKQLEAEKMELQ----SALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAE 794
Query: 290 KMHECAQLGGELDRTRDEASRALQ---RAHEQTETVRKCLQTTVAELERQLAASRAQVST 346
K E Q R D +L R+ + V+K ++ + E+E QL+ + +
Sbjct: 795 KDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAE 854
Query: 347 AEKEREELKNRL 358
A+K+ + L++ L
Sbjct: 855 AQKQVKSLQSLL 866
Score = 41.5 bits (93), Expect = 0.005
Identities = 68/382 (17%), Positives = 146/382 (38%), Gaps = 22/382 (5%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALK-----QCYREAREEID 73
Q E + K ++ E+ +GS+ Q +E+ R + + R AR +++
Sbjct: 290 QQLEERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVE 349
Query: 74 ELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQ 133
+LR+ + + +++ + + A + E ++ R E+ L+ + +
Sbjct: 350 KLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALR 409
Query: 134 EKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYL 193
+K D + ++ + Q+ + E + EL+ + I + +L
Sbjct: 410 KKHA------DSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANL-- 461
Query: 194 VTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRIS 253
M T ED + +S+ + L+ R DEK+ AL IS
Sbjct: 462 -EKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKE-AL----IS 515
Query: 254 QLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELD---RTRDEASR 310
QL ++ ++E LK + ++ A LQ H+C L + + + E R
Sbjct: 516 QLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQR 575
Query: 311 ALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFE 370
L +A+ + R +T + +L ++ +++ +E EE ++ + L +
Sbjct: 576 VLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKH 635
Query: 371 QAQLRILGLQTQVQSLRRTASS 392
+ Q I L V+ A++
Sbjct: 636 RLQNEIEDLMVDVERSNAAAAA 657
Score = 39.9 bits (89), Expect = 0.016
Identities = 76/386 (19%), Positives = 160/386 (41%), Gaps = 47/386 (12%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTL 78
++ E+Q++L + + L+T L + E++ E ++ K+ + +EEI +L
Sbjct: 675 KYEESQSELESSQKEARSLSTELFKLKNAYEESLE---HLETFKRENKNLQEEISDLTEQ 731
Query: 79 MKEQNDQLQDYRV--KYLQAQQL-VEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEK 135
+ + + K L+A+++ ++ + + LE ++K + + K
Sbjct: 732 LGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERK 791
Query: 136 LQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVT 195
L E + K +R+ D+ Q AE + A + E ++ L
Sbjct: 792 LAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEI--QLSHAN 849
Query: 196 TMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQL 255
M + QS + KD + L +++ R D+ L + I+ +
Sbjct: 850 RMAAEAQKQVKSLQSLL----KDTQIQ--LDDAV--------RANDD-----LKENIAIV 890
Query: 256 AENNISLKSEIERLKASVIRTEES-ALANEKRLQEK-------------MHECAQLGGEL 301
N L++E+E L+A V +TE S LA+E+ ++ +++ ++ +L
Sbjct: 891 ERRNNLLQAELEELRAVVEQTERSRKLADEELIETSERVQLLHSQNTSLINQKKKMDADL 950
Query: 302 DRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQ 361
+ + E A+Q E +K + T A + +L + Q ++A ER +K +
Sbjct: 951 SQLQTEVEEAVQECRNAEEKAKKAI-TDAAMMAEEL--KKEQDTSAHLER--MKKNMEQT 1005
Query: 362 MKRLTENFEQA-QLRILGLQTQVQSL 386
+K L ++A Q+ + G + Q+Q L
Sbjct: 1006 IKDLQHRLDEAEQIALKGGKKQLQKL 1031
Score = 31.9 bits (69), Expect = 4.3
Identities = 38/157 (24%), Positives = 71/157 (45%), Gaps = 22/157 (14%)
Query: 225 LHNSLKPPEKPPERGGDEKQMALLNQ---RISQLAENNISLKSEIERLKASV-------- 273
L+ +KP K ER EK+MA + + R+ + E + + + E+E S+
Sbjct: 48 LYFKIKPLLKSAER---EKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQ 104
Query: 274 --IRTEESALAN-EKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTV 330
++ E+ LA+ E+R + + QL ++ + + E T RK L+
Sbjct: 105 LQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRK-LEDEC 163
Query: 331 AELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTE 367
+EL+R + ++ EKE+ +N+ +K LTE
Sbjct: 164 SELKRDIDDLELTLAKVEKEKHATENK----VKNLTE 196
>M58018-1|AAA62830.1| 1935|Homo sapiens beta-myosin heavy chain
protein.
Length = 1935
Score = 45.6 bits (103), Expect = 3e-04
Identities = 62/313 (19%), Positives = 132/313 (42%), Gaps = 20/313 (6%)
Query: 61 LKQCYREAREEIDELRTLMKEQNDQLQDYRVKY----LQAQQLVEEQRRQXXXXXXXNTR 116
L++ Y E E EL+ ++ + N ++ +R KY +Q + +EE +++
Sbjct: 1343 LREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEE 1402
Query: 117 ISEQINLE---IQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQ--AQAIAE--HNAEQ 169
E +N + +++ K + Q ++++L + A L Q+ + +AE E+
Sbjct: 1403 AVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEE 1462
Query: 170 LARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHV-LLHNS 228
EL ++++ + L+ L +L + F + + D T + +
Sbjct: 1463 SQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKT 1522
Query: 229 LKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQ 288
+ EK ++ EK + S L E SL+ E ++ + + + E++L
Sbjct: 1523 IHELEKVRKQLEAEKM-----ELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLA 1577
Query: 289 EKMHECAQLGGELDRTRDEASRALQ---RAHEQTETVRKCLQTTVAELERQLAASRAQVS 345
EK E Q R D +L R+ + V+K ++ + E+E QL+ + +
Sbjct: 1578 EKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAA 1637
Query: 346 TAEKEREELKNRL 358
A+K+ + L++ L
Sbjct: 1638 EAQKQVKSLQSLL 1650
Score = 41.5 bits (93), Expect = 0.005
Identities = 55/339 (16%), Positives = 137/339 (40%), Gaps = 13/339 (3%)
Query: 67 EAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQ 126
+ ++++ EL+ ++E ++L+ R + ++L + R+ +++I+
Sbjct: 1103 QLQKKLKELQARIEELEEELESERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIE 1162
Query: 127 RVKLK---FQEKLQEL--APIPDLLKATQMRLKDAQQAQAIAEH--NAEQLARELNCARE 179
K + FQ+ ++L A + A +R K A + E N +++ ++L +
Sbjct: 1163 MNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKS 1222
Query: 180 KV-VHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIG--RGNKDQTVHVLLHNSLKPPEKPP 236
+ + + ++ + E + + ++ R ++T + + + +
Sbjct: 1223 EFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQT 1282
Query: 237 ERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQ 296
E G +Q+ ISQL ++ ++E LK + ++ A LQ H+C
Sbjct: 1283 ENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDL 1342
Query: 297 LGGELD---RTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREE 353
L + + + E R L +A+ + R +T + +L ++ +++ +E EE
Sbjct: 1343 LREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEE 1402
Query: 354 LKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRRTASS 392
++ + L + + Q I L V+ A++
Sbjct: 1403 AVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAA 1441
Score = 39.5 bits (88), Expect = 0.021
Identities = 76/386 (19%), Positives = 157/386 (40%), Gaps = 47/386 (12%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTL 78
++ E+Q++L + + L+T L + E++ E ++ K+ + +EEI +L
Sbjct: 1459 KYEESQSELESSQKEARSLSTELFKLKNAYEESLE---HLETFKRENKNLQEEISDLTEQ 1515
Query: 79 MKEQNDQLQDYRV--KYLQAQQL-VEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEK 135
+ + + K L+A+++ ++ + + LE ++K + + K
Sbjct: 1516 LGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERK 1575
Query: 136 LQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVT 195
L E + K +R+ D+ Q AE + A + E ++ L
Sbjct: 1576 LAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEI--QLSHAN 1633
Query: 196 TMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQL 255
M + QS + KD + L +++ R D+ L + I+ +
Sbjct: 1634 RMAAEAQKQVKSLQSLL----KDTQIQ--LDDAV--------RANDD-----LKENIAIV 1674
Query: 256 AENNISLKSEIERLKASVIRTEESALANEKRLQEK--------------MHECAQLGGEL 301
N L++E+E L+A V +TE S E+ L E +++ ++ +L
Sbjct: 1675 ERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADL 1734
Query: 302 DRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQ 361
+ + E A+Q E +K + T A + +L + Q ++A ER +K +
Sbjct: 1735 SQLQTEVEEAVQECRNAEEKAKKAI-TDAAMMAEEL--KKEQDTSAHLER--MKKNMEQT 1789
Query: 362 MKRLTENFEQA-QLRILGLQTQVQSL 386
+K L ++A Q+ + G + Q+Q L
Sbjct: 1790 IKDLQHRLDEAEQIALKGGKKQLQKL 1815
Score = 38.7 bits (86), Expect = 0.037
Identities = 75/374 (20%), Positives = 151/374 (40%), Gaps = 30/374 (8%)
Query: 22 ETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQC-YREAREEIDELRTLMK 80
+T ++L ++ + E + E + E E Q + + + EI+
Sbjct: 1521 KTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKD 1580
Query: 81 EQNDQLQDYRVKYLQAQQL-VEEQRRQXXXXXXXNTRISEQIN-LEIQ--RVKLKFQEKL 136
E+ +Q + ++ + + Q ++ + R ++ +N +EIQ E
Sbjct: 1581 EEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQ 1640
Query: 137 QELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTT 196
+++ + LLK TQ++L DA +A + N + R N + + L L V
Sbjct: 1641 KQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAE-------LEELRAVVE 1693
Query: 197 MTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLA 256
T L Q I + Q +H + SL +K + + Q + + + +
Sbjct: 1694 QTERSRKL--AEQELIETSERVQLLH-SQNTSLINQKKKMDADLSQLQTE-VEEAVQECR 1749
Query: 257 ENNISLKSEI--ERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASR-ALQ 313
K I + A ++ E+ A+ +R+++ M + + +L DEA + AL+
Sbjct: 1750 NAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIK---DLQHRLDEAEQIALK 1806
Query: 314 RAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQ 373
+Q + L+ V ELE +L A + + + + K + + R+ K LT E+ +
Sbjct: 1807 GGKKQLQK----LEARVRELENELEAEQKRNAESVKGMRKSERRI----KELTYQTEEDR 1858
Query: 374 LRILGLQTQVQSLR 387
+L LQ V L+
Sbjct: 1859 KNLLRLQDLVDKLQ 1872
Score = 34.7 bits (76), Expect = 0.60
Identities = 67/322 (20%), Positives = 128/322 (39%), Gaps = 23/322 (7%)
Query: 48 KEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQX 107
KE + E + L++ +E ++L+ ++ + D L D + QL++ + +
Sbjct: 860 KEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEER---CDQLIKNKIQLE 916
Query: 108 XXXXXXNTRIS--EQINLEIQRVKLKFQEKLQELA-PIPDL----------LKATQMRLK 154
N R+ E++N E+ K K +++ EL I DL AT+ ++K
Sbjct: 917 AKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVK 976
Query: 155 DAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLY-LVTTMTLTQEDLFGQSQSEIG 213
+ + A + +L +E +E L + V T+T + L Q G
Sbjct: 977 NLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEG 1036
Query: 214 RGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASV 273
+++ V + L + + E + E M L N + QL E E+ L A +
Sbjct: 1037 SLEQEKKVRMDLERAKRKLEGDLKLT-QESIMDLENDK-QQLDERLKKKDFELNALNARI 1094
Query: 274 IRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAEL 333
+E AL ++ LQ+K+ E EL+ + A + + + + L+ L
Sbjct: 1095 --EDEQALGSQ--LQKKLKELQARIEELEEELESERTARAKVEKLRSDLSRELEEISERL 1150
Query: 334 ERQLAASRAQVSTAEKEREELK 355
E A+ Q+ +K E +
Sbjct: 1151 EEAGGATSVQIEMNKKREAEFQ 1172
Score = 31.9 bits (69), Expect = 4.3
Identities = 38/157 (24%), Positives = 71/157 (45%), Gaps = 22/157 (14%)
Query: 225 LHNSLKPPEKPPERGGDEKQMALLNQ---RISQLAENNISLKSEIERLKASV-------- 273
L+ +KP K ER EK+MA + + R+ + E + + + E+E S+
Sbjct: 832 LYFKIKPLLKSAER---EKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQ 888
Query: 274 --IRTEESALAN-EKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTV 330
++ E+ LA+ E+R + + QL ++ + + E T RK L+
Sbjct: 889 LQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRK-LEDEC 947
Query: 331 AELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTE 367
+EL+R + ++ EKE+ +N+ +K LTE
Sbjct: 948 SELKRDIDDLELTLAKVEKEKHATENK----VKNLTE 980
>M57965-1|AAA51837.1| 1935|Homo sapiens beta-myosin heavy chain
protein.
Length = 1935
Score = 45.6 bits (103), Expect = 3e-04
Identities = 62/313 (19%), Positives = 132/313 (42%), Gaps = 20/313 (6%)
Query: 61 LKQCYREAREEIDELRTLMKEQNDQLQDYRVKY----LQAQQLVEEQRRQXXXXXXXNTR 116
L++ Y E E EL+ ++ + N ++ +R KY +Q + +EE +++
Sbjct: 1343 LREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEE 1402
Query: 117 ISEQINLE---IQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQ--AQAIAE--HNAEQ 169
E +N + +++ K + Q ++++L + A L Q+ + +AE E+
Sbjct: 1403 AVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEE 1462
Query: 170 LARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHV-LLHNS 228
EL ++++ + L+ L +L + F + + D T + +
Sbjct: 1463 SQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKT 1522
Query: 229 LKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQ 288
+ EK ++ EK + S L E SL+ E ++ + + + E++L
Sbjct: 1523 IHELEKVRKQLEAEKM-----ELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLA 1577
Query: 289 EKMHECAQLGGELDRTRDEASRALQ---RAHEQTETVRKCLQTTVAELERQLAASRAQVS 345
EK E Q R D +L R+ + V+K ++ + E+E QL+ + +
Sbjct: 1578 EKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAA 1637
Query: 346 TAEKEREELKNRL 358
A+K+ + L++ L
Sbjct: 1638 EAQKQVKSLQSLL 1650
Score = 41.5 bits (93), Expect = 0.005
Identities = 55/339 (16%), Positives = 137/339 (40%), Gaps = 13/339 (3%)
Query: 67 EAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQ 126
+ ++++ EL+ ++E ++L+ R + ++L + R+ +++I+
Sbjct: 1103 QLQKKLKELQARIEELEEELESERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIE 1162
Query: 127 RVKLK---FQEKLQEL--APIPDLLKATQMRLKDAQQAQAIAEH--NAEQLARELNCARE 179
K + FQ+ ++L A + A +R K A + E N +++ ++L +
Sbjct: 1163 MNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKS 1222
Query: 180 KV-VHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIG--RGNKDQTVHVLLHNSLKPPEKPP 236
+ + + ++ + E + + ++ R ++T + + + +
Sbjct: 1223 EFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQT 1282
Query: 237 ERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQ 296
E G +Q+ ISQL ++ ++E LK + ++ A LQ H+C
Sbjct: 1283 ENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDL 1342
Query: 297 LGGELD---RTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREE 353
L + + + E R L +A+ + R +T + +L ++ +++ +E EE
Sbjct: 1343 LREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEE 1402
Query: 354 LKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRRTASS 392
++ + L + + Q I L V+ A++
Sbjct: 1403 AVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAA 1441
Score = 39.5 bits (88), Expect = 0.021
Identities = 76/386 (19%), Positives = 157/386 (40%), Gaps = 47/386 (12%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTL 78
++ E+Q++L + + L+T L + E++ E ++ K+ + +EEI +L
Sbjct: 1459 KYEESQSELESSQKEARSLSTELFKLKNAYEESLE---HLETFKRENKNLQEEISDLTEQ 1515
Query: 79 MKEQNDQLQDYRV--KYLQAQQL-VEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEK 135
+ + + K L+A+++ ++ + + LE ++K + + K
Sbjct: 1516 LGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERK 1575
Query: 136 LQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVT 195
L E + K +R+ D+ Q AE + A + E ++ L
Sbjct: 1576 LAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEI--QLSHAN 1633
Query: 196 TMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQL 255
M + QS + KD + L +++ R D+ L + I+ +
Sbjct: 1634 RMAAEAQKQVKSLQSLL----KDTQIQ--LDDAV--------RANDD-----LKENIAIV 1674
Query: 256 AENNISLKSEIERLKASVIRTEESALANEKRLQEK--------------MHECAQLGGEL 301
N L++E+E L+A V +TE S E+ L E +++ ++ +L
Sbjct: 1675 ERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADL 1734
Query: 302 DRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQ 361
+ + E A+Q E +K + T A + +L + Q ++A ER +K +
Sbjct: 1735 SQLQTEVEEAVQECRNAEEKAKKAI-TDAAMMAEEL--KKEQDTSAHLER--MKKNMEQT 1789
Query: 362 MKRLTENFEQA-QLRILGLQTQVQSL 386
+K L ++A Q+ + G + Q+Q L
Sbjct: 1790 IKDLQHRLDEAEQIALKGGKKQLQKL 1815
Score = 38.7 bits (86), Expect = 0.037
Identities = 75/374 (20%), Positives = 151/374 (40%), Gaps = 30/374 (8%)
Query: 22 ETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQC-YREAREEIDELRTLMK 80
+T ++L ++ + E + E + E E Q + + + EI+
Sbjct: 1521 KTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKD 1580
Query: 81 EQNDQLQDYRVKYLQAQQL-VEEQRRQXXXXXXXNTRISEQIN-LEIQ--RVKLKFQEKL 136
E+ +Q + ++ + + Q ++ + R ++ +N +EIQ E
Sbjct: 1581 EEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQ 1640
Query: 137 QELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTT 196
+++ + LLK TQ++L DA +A + N + R N + + L L V
Sbjct: 1641 KQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAE-------LEELRAVVE 1693
Query: 197 MTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLA 256
T L Q I + Q +H + SL +K + + Q + + + +
Sbjct: 1694 QTERSRKL--AEQELIETSERVQLLH-SQNTSLINQKKKMDADLSQLQTE-VEEAVQECR 1749
Query: 257 ENNISLKSEI--ERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASR-ALQ 313
K I + A ++ E+ A+ +R+++ M + + +L DEA + AL+
Sbjct: 1750 NAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIK---DLQHRLDEAEQIALK 1806
Query: 314 RAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQ 373
+Q + L+ V ELE +L A + + + + K + + R+ K LT E+ +
Sbjct: 1807 GGKKQLQK----LEARVRELENELEAEQKRNAESVKGMRKSERRI----KELTYQTEEDR 1858
Query: 374 LRILGLQTQVQSLR 387
+L LQ V L+
Sbjct: 1859 KNLLRLQDLVDKLQ 1872
Score = 34.7 bits (76), Expect = 0.60
Identities = 67/322 (20%), Positives = 128/322 (39%), Gaps = 23/322 (7%)
Query: 48 KEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQX 107
KE + E + L++ +E ++L+ ++ + D L D + QL++ + +
Sbjct: 860 KEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEER---CDQLIKNKIQLE 916
Query: 108 XXXXXXNTRIS--EQINLEIQRVKLKFQEKLQELA-PIPDL----------LKATQMRLK 154
N R+ E++N E+ K K +++ EL I DL AT+ ++K
Sbjct: 917 AKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVK 976
Query: 155 DAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLY-LVTTMTLTQEDLFGQSQSEIG 213
+ + A + +L +E +E L + V T+T + L Q G
Sbjct: 977 NLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEG 1036
Query: 214 RGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASV 273
+++ V + L + + E + E M L N + QL E E+ L A +
Sbjct: 1037 SLEQEKKVRMDLERAKRKLEGDLKLT-QESIMDLENDK-QQLDERLKKKDFELNALNARI 1094
Query: 274 IRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAEL 333
+E AL ++ LQ+K+ E EL+ + A + + + + L+ L
Sbjct: 1095 --EDEQALGSQ--LQKKLKELQARIEELEEELESERTARAKVEKLRSDLSRELEEISERL 1150
Query: 334 ERQLAASRAQVSTAEKEREELK 355
E A+ Q+ +K E +
Sbjct: 1151 EEAGGATSVQIEMNKKREAEFQ 1172
Score = 31.9 bits (69), Expect = 4.3
Identities = 38/157 (24%), Positives = 71/157 (45%), Gaps = 22/157 (14%)
Query: 225 LHNSLKPPEKPPERGGDEKQMALLNQ---RISQLAENNISLKSEIERLKASV-------- 273
L+ +KP K ER EK+MA + + R+ + E + + + E+E S+
Sbjct: 832 LYFKIKPLLKSAER---EKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQ 888
Query: 274 --IRTEESALAN-EKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTV 330
++ E+ LA+ E+R + + QL ++ + + E T RK L+
Sbjct: 889 LQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRK-LEDEC 947
Query: 331 AELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTE 367
+EL+R + ++ EKE+ +N+ +K LTE
Sbjct: 948 SELKRDIDDLELTLAKVEKEKHATENK----VKNLTE 980
>M25139-1|AAA60385.1| 611|Homo sapiens myosin heavy chain
beta-subunit protein.
Length = 611
Score = 45.6 bits (103), Expect = 3e-04
Identities = 62/313 (19%), Positives = 132/313 (42%), Gaps = 20/313 (6%)
Query: 61 LKQCYREAREEIDELRTLMKEQNDQLQDYRVKY----LQAQQLVEEQRRQXXXXXXXNTR 116
L++ Y E E EL+ ++ + N ++ +R KY +Q + +EE +++
Sbjct: 19 LREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEE 78
Query: 117 ISEQINLE---IQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQ--AQAIAE--HNAEQ 169
E +N + +++ K + Q ++++L + A L Q+ + +AE E+
Sbjct: 79 AVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEE 138
Query: 170 LARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHV-LLHNS 228
EL ++++ + L+ L +L + F + + D T + +
Sbjct: 139 SQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKT 198
Query: 229 LKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQ 288
+ EK ++ EK + S L E SL+ E ++ + + + E++L
Sbjct: 199 IHELEKVRKQLEAEKM-----ELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLA 253
Query: 289 EKMHECAQLGGELDRTRDEASRALQ---RAHEQTETVRKCLQTTVAELERQLAASRAQVS 345
EK E Q R D +L R+ + V+K ++ + E+E QL+ + +
Sbjct: 254 EKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAA 313
Query: 346 TAEKEREELKNRL 358
A+K+ + L++ L
Sbjct: 314 EAQKQVKSLQSLL 326
Score = 38.7 bits (86), Expect = 0.037
Identities = 75/386 (19%), Positives = 157/386 (40%), Gaps = 47/386 (12%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTL 78
++ E+Q++L + + L+T L + E++ E ++ K+ + +EEI +L
Sbjct: 135 KYEESQSELESSQKEARSLSTELFKLKNAYEESLE---HLETFKRENKNLQEEISDLTEQ 191
Query: 79 MKEQNDQLQDYRV--KYLQAQQL-VEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEK 135
+ + + K L+A+++ ++ + + LE ++K + + K
Sbjct: 192 LGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERK 251
Query: 136 LQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVT 195
L E + K +R+ D+ Q AE + A + E ++ L
Sbjct: 252 LAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEI--QLSHAN 309
Query: 196 TMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQL 255
M + QS + KD + L +++ R D+ L + I+ +
Sbjct: 310 RMAAEAQKQVKSLQSLL----KDTQIQ--LDDAV--------RANDD-----LKENIAIV 350
Query: 256 AENNISLKSEIERLKASVIRTEESALANEKRLQEK--------------MHECAQLGGEL 301
N L++E+E L+A V +TE S ++ L E +++ ++ +L
Sbjct: 351 ERRNNLLQAELEELRAVVEQTERSRKLADRELIETSERVQLLHSQNTSLINQKKKMDADL 410
Query: 302 DRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQ 361
+ + E A+Q E +K + T A + +L + Q ++A ER +K +
Sbjct: 411 SQLQTEVEEAVQECRNAEEKAKKAI-TDAAMMAEEL--KKEQDTSAHLER--MKKNMEQT 465
Query: 362 MKRLTENFEQA-QLRILGLQTQVQSL 386
+K L ++A Q+ + G + Q+Q L
Sbjct: 466 IKDLQHRLDEAEQIALKGGKKQLQKL 491
Score = 37.1 bits (82), Expect = 0.11
Identities = 74/374 (19%), Positives = 151/374 (40%), Gaps = 30/374 (8%)
Query: 22 ETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQC-YREAREEIDELRTLMK 80
+T ++L ++ + E + E + E E Q + + + EI+
Sbjct: 197 KTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKD 256
Query: 81 EQNDQLQDYRVKYLQAQQL-VEEQRRQXXXXXXXNTRISEQIN-LEIQ--RVKLKFQEKL 136
E+ +Q + ++ + + Q ++ + R ++ +N +EIQ E
Sbjct: 257 EEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQ 316
Query: 137 QELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTT 196
+++ + LLK TQ++L DA +A + N + R N + + L L V
Sbjct: 317 KQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAE-------LEELRAVVE 369
Query: 197 MTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLA 256
T L + I + Q +H + SL +K + + Q + + + +
Sbjct: 370 QTERSRKL--ADRELIETSERVQLLH-SQNTSLINQKKKMDADLSQLQTE-VEEAVQECR 425
Query: 257 ENNISLKSEI--ERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASR-ALQ 313
K I + A ++ E+ A+ +R+++ M + + +L DEA + AL+
Sbjct: 426 NAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIK---DLQHRLDEAEQIALK 482
Query: 314 RAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQ 373
+Q + L+ V ELE +L A + + + + K + + R+ K LT E+ +
Sbjct: 483 GGKKQLQK----LEARVRELENELEAEQKRNAESVKGMRKSERRI----KELTYQTEEDR 534
Query: 374 LRILGLQTQVQSLR 387
+L LQ V L+
Sbjct: 535 KNLLRLQDLVDKLQ 548
>EF179180-1|ABN05283.1| 1935|Homo sapiens myosin, heavy chain 7,
cardiac muscle, beta protein.
Length = 1935
Score = 45.6 bits (103), Expect = 3e-04
Identities = 62/313 (19%), Positives = 132/313 (42%), Gaps = 20/313 (6%)
Query: 61 LKQCYREAREEIDELRTLMKEQNDQLQDYRVKY----LQAQQLVEEQRRQXXXXXXXNTR 116
L++ Y E E EL+ ++ + N ++ +R KY +Q + +EE +++
Sbjct: 1343 LREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEE 1402
Query: 117 ISEQINLE---IQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQ--AQAIAE--HNAEQ 169
E +N + +++ K + Q ++++L + A L Q+ + +AE E+
Sbjct: 1403 AVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEE 1462
Query: 170 LARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHV-LLHNS 228
EL ++++ + L+ L +L + F + + D T + +
Sbjct: 1463 SQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKT 1522
Query: 229 LKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQ 288
+ EK ++ EK + S L E SL+ E ++ + + + E++L
Sbjct: 1523 IHELEKVRKQLEAEKM-----ELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLA 1577
Query: 289 EKMHECAQLGGELDRTRDEASRALQ---RAHEQTETVRKCLQTTVAELERQLAASRAQVS 345
EK E Q R D +L R+ + V+K ++ + E+E QL+ + +
Sbjct: 1578 EKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAA 1637
Query: 346 TAEKEREELKNRL 358
A+K+ + L++ L
Sbjct: 1638 EAQKQVKSLQSLL 1650
Score = 40.7 bits (91), Expect = 0.009
Identities = 55/339 (16%), Positives = 137/339 (40%), Gaps = 13/339 (3%)
Query: 67 EAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQ 126
+ ++++ EL+ ++E ++L+ R + ++L + R+ +++I+
Sbjct: 1103 QLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIE 1162
Query: 127 RVKLK---FQEKLQEL--APIPDLLKATQMRLKDAQQAQAIAEH--NAEQLARELNCARE 179
K + FQ+ ++L A + A +R K A + E N +++ ++L +
Sbjct: 1163 MNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKS 1222
Query: 180 KV-VHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIG--RGNKDQTVHVLLHNSLKPPEKPP 236
+ + + ++ + E + + ++ R ++T + + + +
Sbjct: 1223 EFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQT 1282
Query: 237 ERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQ 296
E G +Q+ ISQL ++ ++E LK + ++ A LQ H+C
Sbjct: 1283 ENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDL 1342
Query: 297 LGGELD---RTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREE 353
L + + + E R L +A+ + R +T + +L ++ +++ +E EE
Sbjct: 1343 LREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEE 1402
Query: 354 LKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRRTASS 392
++ + L + + Q I L V+ A++
Sbjct: 1403 AVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAA 1441
Score = 39.5 bits (88), Expect = 0.021
Identities = 76/386 (19%), Positives = 157/386 (40%), Gaps = 47/386 (12%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTL 78
++ E+Q++L + + L+T L + E++ E ++ K+ + +EEI +L
Sbjct: 1459 KYEESQSELESSQKEARSLSTELFKLKNAYEESLE---HLETFKRENKNLQEEISDLTEQ 1515
Query: 79 MKEQNDQLQDYRV--KYLQAQQL-VEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEK 135
+ + + K L+A+++ ++ + + LE ++K + + K
Sbjct: 1516 LGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERK 1575
Query: 136 LQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVT 195
L E + K +R+ D+ Q AE + A + E ++ L
Sbjct: 1576 LAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEI--QLSHAN 1633
Query: 196 TMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQL 255
M + QS + KD + L +++ R D+ L + I+ +
Sbjct: 1634 RMAAEAQKQVKSLQSLL----KDTQIQ--LDDAV--------RANDD-----LKENIAIV 1674
Query: 256 AENNISLKSEIERLKASVIRTEESALANEKRLQEK--------------MHECAQLGGEL 301
N L++E+E L+A V +TE S E+ L E +++ ++ +L
Sbjct: 1675 ERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADL 1734
Query: 302 DRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQ 361
+ + E A+Q E +K + T A + +L + Q ++A ER +K +
Sbjct: 1735 SQLQTEVEEAVQECRNAEEKAKKAI-TDAAMMAEEL--KKEQDTSAHLER--MKKNMEQT 1789
Query: 362 MKRLTENFEQA-QLRILGLQTQVQSL 386
+K L ++A Q+ + G + Q+Q L
Sbjct: 1790 IKDLQHRLDEAEQIALKGGKKQLQKL 1815
Score = 38.7 bits (86), Expect = 0.037
Identities = 75/374 (20%), Positives = 151/374 (40%), Gaps = 30/374 (8%)
Query: 22 ETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQC-YREAREEIDELRTLMK 80
+T ++L ++ + E + E + E E Q + + + EI+
Sbjct: 1521 KTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKD 1580
Query: 81 EQNDQLQDYRVKYLQAQQL-VEEQRRQXXXXXXXNTRISEQIN-LEIQ--RVKLKFQEKL 136
E+ +Q + ++ + + Q ++ + R ++ +N +EIQ E
Sbjct: 1581 EEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQ 1640
Query: 137 QELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTT 196
+++ + LLK TQ++L DA +A + N + R N + + L L V
Sbjct: 1641 KQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAE-------LEELRAVVE 1693
Query: 197 MTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLA 256
T L Q I + Q +H + SL +K + + Q + + + +
Sbjct: 1694 QTERSRKL--AEQELIETSERVQLLH-SQNTSLINQKKKMDADLSQLQTE-VEEAVQECR 1749
Query: 257 ENNISLKSEI--ERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASR-ALQ 313
K I + A ++ E+ A+ +R+++ M + + +L DEA + AL+
Sbjct: 1750 NAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIK---DLQHRLDEAEQIALK 1806
Query: 314 RAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQ 373
+Q + L+ V ELE +L A + + + + K + + R+ K LT E+ +
Sbjct: 1807 GGKKQLQK----LEARVRELENELEAEQKRNAESVKGMRKSERRI----KELTYQTEEDR 1858
Query: 374 LRILGLQTQVQSLR 387
+L LQ V L+
Sbjct: 1859 KNLLRLQDLVDKLQ 1872
Score = 34.3 bits (75), Expect = 0.80
Identities = 67/322 (20%), Positives = 128/322 (39%), Gaps = 23/322 (7%)
Query: 48 KEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQX 107
KE + E + L++ +E ++L+ ++ + D L D + QL++ + +
Sbjct: 860 KEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEER---CDQLIKNKIQLE 916
Query: 108 XXXXXXNTRIS--EQINLEIQRVKLKFQEKLQELA-PIPDL----------LKATQMRLK 154
N R+ E++N E+ K K +++ EL I DL AT+ ++K
Sbjct: 917 AKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVK 976
Query: 155 DAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLY-LVTTMTLTQEDLFGQSQSEIG 213
+ + A + +L +E +E L + V T+T + L Q G
Sbjct: 977 NLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEG 1036
Query: 214 RGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASV 273
+++ V + L + + E + E M L N + QL E E+ L A +
Sbjct: 1037 SLEQEKKVRMDLERAKRKLEGDLKLT-QESIMDLENDK-QQLDERLKKKDFELNALNARI 1094
Query: 274 IRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAEL 333
+E AL ++ LQ+K+ E EL+ + A + + + + L+ L
Sbjct: 1095 --EDEQALGSQ--LQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERL 1150
Query: 334 ERQLAASRAQVSTAEKEREELK 355
E A+ Q+ +K E +
Sbjct: 1151 EEAGGATSVQIEMNKKREAEFQ 1172
Score = 31.9 bits (69), Expect = 4.3
Identities = 38/157 (24%), Positives = 71/157 (45%), Gaps = 22/157 (14%)
Query: 225 LHNSLKPPEKPPERGGDEKQMALLNQ---RISQLAENNISLKSEIERLKASV-------- 273
L+ +KP K ER EK+MA + + R+ + E + + + E+E S+
Sbjct: 832 LYFKIKPLLKSAER---EKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQ 888
Query: 274 --IRTEESALAN-EKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTV 330
++ E+ LA+ E+R + + QL ++ + + E T RK L+
Sbjct: 889 LQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRK-LEDEC 947
Query: 331 AELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTE 367
+EL+R + ++ EKE+ +N+ +K LTE
Sbjct: 948 SELKRDIDDLELTLAKVEKEKHATENK----VKNLTE 980
>BC112173-1|AAI12174.1| 1935|Homo sapiens myosin, heavy chain 7,
cardiac muscle, beta protein.
Length = 1935
Score = 45.6 bits (103), Expect = 3e-04
Identities = 62/313 (19%), Positives = 132/313 (42%), Gaps = 20/313 (6%)
Query: 61 LKQCYREAREEIDELRTLMKEQNDQLQDYRVKY----LQAQQLVEEQRRQXXXXXXXNTR 116
L++ Y E E EL+ ++ + N ++ +R KY +Q + +EE +++
Sbjct: 1343 LREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEE 1402
Query: 117 ISEQINLE---IQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQ--AQAIAE--HNAEQ 169
E +N + +++ K + Q ++++L + A L Q+ + +AE E+
Sbjct: 1403 AVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEE 1462
Query: 170 LARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHV-LLHNS 228
EL ++++ + L+ L +L + F + + D T + +
Sbjct: 1463 SQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKT 1522
Query: 229 LKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQ 288
+ EK ++ EK + S L E SL+ E ++ + + + E++L
Sbjct: 1523 IHELEKVRKQLEAEKM-----ELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLA 1577
Query: 289 EKMHECAQLGGELDRTRDEASRALQ---RAHEQTETVRKCLQTTVAELERQLAASRAQVS 345
EK E Q R D +L R+ + V+K ++ + E+E QL+ + +
Sbjct: 1578 EKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAA 1637
Query: 346 TAEKEREELKNRL 358
A+K+ + L++ L
Sbjct: 1638 EAQKQVKSLQSLL 1650
Score = 40.7 bits (91), Expect = 0.009
Identities = 55/339 (16%), Positives = 137/339 (40%), Gaps = 13/339 (3%)
Query: 67 EAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQ 126
+ ++++ EL+ ++E ++L+ R + ++L + R+ +++I+
Sbjct: 1103 QLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIE 1162
Query: 127 RVKLK---FQEKLQEL--APIPDLLKATQMRLKDAQQAQAIAEH--NAEQLARELNCARE 179
K + FQ+ ++L A + A +R K A + E N +++ ++L +
Sbjct: 1163 MNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKS 1222
Query: 180 KV-VHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIG--RGNKDQTVHVLLHNSLKPPEKPP 236
+ + + ++ + E + + ++ R ++T + + + +
Sbjct: 1223 EFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQT 1282
Query: 237 ERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQ 296
E G +Q+ ISQL ++ ++E LK + ++ A LQ H+C
Sbjct: 1283 ENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDL 1342
Query: 297 LGGELD---RTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREE 353
L + + + E R L +A+ + R +T + +L ++ +++ +E EE
Sbjct: 1343 LREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEE 1402
Query: 354 LKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRRTASS 392
++ + L + + Q I L V+ A++
Sbjct: 1403 AVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAA 1441
Score = 39.5 bits (88), Expect = 0.021
Identities = 76/386 (19%), Positives = 157/386 (40%), Gaps = 47/386 (12%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTL 78
++ E+Q++L + + L+T L + E++ E ++ K+ + +EEI +L
Sbjct: 1459 KYEESQSELESSQKEARSLSTELFKLKNAYEESLE---HLETFKRENKNLQEEISDLTEQ 1515
Query: 79 MKEQNDQLQDYRV--KYLQAQQL-VEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEK 135
+ + + K L+A+++ ++ + + LE ++K + + K
Sbjct: 1516 LGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERK 1575
Query: 136 LQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVT 195
L E + K +R+ D+ Q AE + A + E ++ L
Sbjct: 1576 LAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEI--QLSHAN 1633
Query: 196 TMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQL 255
M + QS + KD + L +++ R D+ L + I+ +
Sbjct: 1634 RMAAEAQKQVKSLQSLL----KDTQIQ--LDDAV--------RANDD-----LKENIAIV 1674
Query: 256 AENNISLKSEIERLKASVIRTEESALANEKRLQEK--------------MHECAQLGGEL 301
N L++E+E L+A V +TE S E+ L E +++ ++ +L
Sbjct: 1675 ERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADL 1734
Query: 302 DRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQ 361
+ + E A+Q E +K + T A + +L + Q ++A ER +K +
Sbjct: 1735 SQLQTEVEEAVQECRNAEEKAKKAI-TDAAMMAEEL--KKEQDTSAHLER--MKKNMEQT 1789
Query: 362 MKRLTENFEQA-QLRILGLQTQVQSL 386
+K L ++A Q+ + G + Q+Q L
Sbjct: 1790 IKDLQHRLDEAEQIALKGGKKQLQKL 1815
Score = 38.7 bits (86), Expect = 0.037
Identities = 75/374 (20%), Positives = 151/374 (40%), Gaps = 30/374 (8%)
Query: 22 ETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQC-YREAREEIDELRTLMK 80
+T ++L ++ + E + E + E E Q + + + EI+
Sbjct: 1521 KTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKD 1580
Query: 81 EQNDQLQDYRVKYLQAQQL-VEEQRRQXXXXXXXNTRISEQIN-LEIQ--RVKLKFQEKL 136
E+ +Q + ++ + + Q ++ + R ++ +N +EIQ E
Sbjct: 1581 EEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQ 1640
Query: 137 QELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTT 196
+++ + LLK TQ++L DA +A + N + R N + + L L V
Sbjct: 1641 KQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAE-------LEELRAVVE 1693
Query: 197 MTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLA 256
T L Q I + Q +H + SL +K + + Q + + + +
Sbjct: 1694 QTERSRKL--AEQELIETSERVQLLH-SQNTSLINQKKKMDADLSQLQTE-VEEAVQECR 1749
Query: 257 ENNISLKSEI--ERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASR-ALQ 313
K I + A ++ E+ A+ +R+++ M + + +L DEA + AL+
Sbjct: 1750 NAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIK---DLQHRLDEAEQIALK 1806
Query: 314 RAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQ 373
+Q + L+ V ELE +L A + + + + K + + R+ K LT E+ +
Sbjct: 1807 GGKKQLQK----LEARVRELENELEAEQKRNAESVKGMRKSERRI----KELTYQTEEDR 1858
Query: 374 LRILGLQTQVQSLR 387
+L LQ V L+
Sbjct: 1859 KNLLRLQDLVDKLQ 1872
Score = 34.3 bits (75), Expect = 0.80
Identities = 67/322 (20%), Positives = 128/322 (39%), Gaps = 23/322 (7%)
Query: 48 KEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQX 107
KE + E + L++ +E ++L+ ++ + D L D + QL++ + +
Sbjct: 860 KEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEER---CDQLIKNKIQLE 916
Query: 108 XXXXXXNTRIS--EQINLEIQRVKLKFQEKLQELA-PIPDL----------LKATQMRLK 154
N R+ E++N E+ K K +++ EL I DL AT+ ++K
Sbjct: 917 AKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVK 976
Query: 155 DAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLY-LVTTMTLTQEDLFGQSQSEIG 213
+ + A + +L +E +E L + V T+T + L Q G
Sbjct: 977 NLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEG 1036
Query: 214 RGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASV 273
+++ V + L + + E + E M L N + QL E E+ L A +
Sbjct: 1037 SLEQEKKVRMDLERAKRKLEGDLKLT-QESIMDLENDK-QQLDERLKKKDFELNALNARI 1094
Query: 274 IRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAEL 333
+E AL ++ LQ+K+ E EL+ + A + + + + L+ L
Sbjct: 1095 --EDEQALGSQ--LQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERL 1150
Query: 334 ERQLAASRAQVSTAEKEREELK 355
E A+ Q+ +K E +
Sbjct: 1151 EEAGGATSVQIEMNKKREAEFQ 1172
Score = 31.9 bits (69), Expect = 4.3
Identities = 38/157 (24%), Positives = 71/157 (45%), Gaps = 22/157 (14%)
Query: 225 LHNSLKPPEKPPERGGDEKQMALLNQ---RISQLAENNISLKSEIERLKASV-------- 273
L+ +KP K ER EK+MA + + R+ + E + + + E+E S+
Sbjct: 832 LYFKIKPLLKSAER---EKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQ 888
Query: 274 --IRTEESALAN-EKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTV 330
++ E+ LA+ E+R + + QL ++ + + E T RK L+
Sbjct: 889 LQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRK-LEDEC 947
Query: 331 AELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTE 367
+EL+R + ++ EKE+ +N+ +K LTE
Sbjct: 948 SELKRDIDDLELTLAKVEKEKHATENK----VKNLTE 980
>BC112171-1|AAI12172.1| 1935|Homo sapiens myosin, heavy chain 7,
cardiac muscle, beta protein.
Length = 1935
Score = 45.6 bits (103), Expect = 3e-04
Identities = 62/313 (19%), Positives = 132/313 (42%), Gaps = 20/313 (6%)
Query: 61 LKQCYREAREEIDELRTLMKEQNDQLQDYRVKY----LQAQQLVEEQRRQXXXXXXXNTR 116
L++ Y E E EL+ ++ + N ++ +R KY +Q + +EE +++
Sbjct: 1343 LREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEE 1402
Query: 117 ISEQINLE---IQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQ--AQAIAE--HNAEQ 169
E +N + +++ K + Q ++++L + A L Q+ + +AE E+
Sbjct: 1403 AVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEE 1462
Query: 170 LARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHV-LLHNS 228
EL ++++ + L+ L +L + F + + D T + +
Sbjct: 1463 SQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKT 1522
Query: 229 LKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQ 288
+ EK ++ EK + S L E SL+ E ++ + + + E++L
Sbjct: 1523 IHELEKVRKQLEAEKM-----ELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLA 1577
Query: 289 EKMHECAQLGGELDRTRDEASRALQ---RAHEQTETVRKCLQTTVAELERQLAASRAQVS 345
EK E Q R D +L R+ + V+K ++ + E+E QL+ + +
Sbjct: 1578 EKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAA 1637
Query: 346 TAEKEREELKNRL 358
A+K+ + L++ L
Sbjct: 1638 EAQKQVKSLQSLL 1650
Score = 40.7 bits (91), Expect = 0.009
Identities = 55/339 (16%), Positives = 137/339 (40%), Gaps = 13/339 (3%)
Query: 67 EAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQ 126
+ ++++ EL+ ++E ++L+ R + ++L + R+ +++I+
Sbjct: 1103 QLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIE 1162
Query: 127 RVKLK---FQEKLQEL--APIPDLLKATQMRLKDAQQAQAIAEH--NAEQLARELNCARE 179
K + FQ+ ++L A + A +R K A + E N +++ ++L +
Sbjct: 1163 MNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKS 1222
Query: 180 KV-VHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIG--RGNKDQTVHVLLHNSLKPPEKPP 236
+ + + ++ + E + + ++ R ++T + + + +
Sbjct: 1223 EFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQT 1282
Query: 237 ERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQ 296
E G +Q+ ISQL ++ ++E LK + ++ A LQ H+C
Sbjct: 1283 ENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDL 1342
Query: 297 LGGELD---RTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREE 353
L + + + E R L +A+ + R +T + +L ++ +++ +E EE
Sbjct: 1343 LREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEE 1402
Query: 354 LKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRRTASS 392
++ + L + + Q I L V+ A++
Sbjct: 1403 AVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAA 1441
Score = 39.5 bits (88), Expect = 0.021
Identities = 76/386 (19%), Positives = 157/386 (40%), Gaps = 47/386 (12%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTL 78
++ E+Q++L + + L+T L + E++ E ++ K+ + +EEI +L
Sbjct: 1459 KYEESQSELESSQKEARSLSTELFKLKNAYEESLE---HLETFKRENKNLQEEISDLTEQ 1515
Query: 79 MKEQNDQLQDYRV--KYLQAQQL-VEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEK 135
+ + + K L+A+++ ++ + + LE ++K + + K
Sbjct: 1516 LGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERK 1575
Query: 136 LQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVT 195
L E + K +R+ D+ Q AE + A + E ++ L
Sbjct: 1576 LAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEI--QLSHAN 1633
Query: 196 TMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQL 255
M + QS + KD + L +++ R D+ L + I+ +
Sbjct: 1634 RMAAEAQKQVKSLQSLL----KDTQIQ--LDDAV--------RANDD-----LKENIAIV 1674
Query: 256 AENNISLKSEIERLKASVIRTEESALANEKRLQEK--------------MHECAQLGGEL 301
N L++E+E L+A V +TE S E+ L E +++ ++ +L
Sbjct: 1675 ERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADL 1734
Query: 302 DRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQ 361
+ + E A+Q E +K + T A + +L + Q ++A ER +K +
Sbjct: 1735 SQLQTEVEEAVQECRNAEEKAKKAI-TDAAMMAEEL--KKEQDTSAHLER--MKKNMEQT 1789
Query: 362 MKRLTENFEQA-QLRILGLQTQVQSL 386
+K L ++A Q+ + G + Q+Q L
Sbjct: 1790 IKDLQHRLDEAEQIALKGGKKQLQKL 1815
Score = 38.7 bits (86), Expect = 0.037
Identities = 75/374 (20%), Positives = 151/374 (40%), Gaps = 30/374 (8%)
Query: 22 ETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQC-YREAREEIDELRTLMK 80
+T ++L ++ + E + E + E E Q + + + EI+
Sbjct: 1521 KTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKD 1580
Query: 81 EQNDQLQDYRVKYLQAQQL-VEEQRRQXXXXXXXNTRISEQIN-LEIQ--RVKLKFQEKL 136
E+ +Q + ++ + + Q ++ + R ++ +N +EIQ E
Sbjct: 1581 EEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQ 1640
Query: 137 QELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTT 196
+++ + LLK TQ++L DA +A + N + R N + + L L V
Sbjct: 1641 KQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAE-------LEELRAVVE 1693
Query: 197 MTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLA 256
T L Q I + Q +H + SL +K + + Q + + + +
Sbjct: 1694 QTERSRKL--AEQELIETSERVQLLH-SQNTSLINQKKKMDADLSQLQTE-VEEAVQECR 1749
Query: 257 ENNISLKSEI--ERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASR-ALQ 313
K I + A ++ E+ A+ +R+++ M + + +L DEA + AL+
Sbjct: 1750 NAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIK---DLQHRLDEAEQIALK 1806
Query: 314 RAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQ 373
+Q + L+ V ELE +L A + + + + K + + R+ K LT E+ +
Sbjct: 1807 GGKKQLQK----LEARVRELENELEAEQKRNAESVKGMRKSERRI----KELTYQTEEDR 1858
Query: 374 LRILGLQTQVQSLR 387
+L LQ V L+
Sbjct: 1859 KNLLRLQDLVDKLQ 1872
Score = 34.3 bits (75), Expect = 0.80
Identities = 67/322 (20%), Positives = 128/322 (39%), Gaps = 23/322 (7%)
Query: 48 KEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQX 107
KE + E + L++ +E ++L+ ++ + D L D + QL++ + +
Sbjct: 860 KEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEER---CDQLIKNKIQLE 916
Query: 108 XXXXXXNTRIS--EQINLEIQRVKLKFQEKLQELA-PIPDL----------LKATQMRLK 154
N R+ E++N E+ K K +++ EL I DL AT+ ++K
Sbjct: 917 AKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVK 976
Query: 155 DAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLY-LVTTMTLTQEDLFGQSQSEIG 213
+ + A + +L +E +E L + V T+T + L Q G
Sbjct: 977 NLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEG 1036
Query: 214 RGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASV 273
+++ V + L + + E + E M L N + QL E E+ L A +
Sbjct: 1037 SLEQEKKVRMDLERAKRKLEGDLKLT-QESIMDLENDK-QQLDERLKKKDFELNALNARI 1094
Query: 274 IRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAEL 333
+E AL ++ LQ+K+ E EL+ + A + + + + L+ L
Sbjct: 1095 --EDEQALGSQ--LQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERL 1150
Query: 334 ERQLAASRAQVSTAEKEREELK 355
E A+ Q+ +K E +
Sbjct: 1151 EEAGGATSVQIEMNKKREAEFQ 1172
Score = 31.9 bits (69), Expect = 4.3
Identities = 38/157 (24%), Positives = 71/157 (45%), Gaps = 22/157 (14%)
Query: 225 LHNSLKPPEKPPERGGDEKQMALLNQ---RISQLAENNISLKSEIERLKASV-------- 273
L+ +KP K ER EK+MA + + R+ + E + + + E+E S+
Sbjct: 832 LYFKIKPLLKSAER---EKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQ 888
Query: 274 --IRTEESALAN-EKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTV 330
++ E+ LA+ E+R + + QL ++ + + E T RK L+
Sbjct: 889 LQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRK-LEDEC 947
Query: 331 AELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTE 367
+EL+R + ++ EKE+ +N+ +K LTE
Sbjct: 948 SELKRDIDDLELTLAKVEKEKHATENK----VKNLTE 980
>BC007570-1|AAH07570.1| 649|Homo sapiens FBF1 protein protein.
Length = 649
Score = 45.6 bits (103), Expect = 3e-04
Identities = 79/350 (22%), Positives = 147/350 (42%), Gaps = 25/350 (7%)
Query: 17 RCQHRETQNKLRELEMKFEGLAT----HTNMLMGSKEQAFEQEVNVRALKQCYREAREEI 72
R H E +L+ L+ + AT HT L Q + ++ L +
Sbjct: 222 RRDHEEQLQRLKLLKDREVDAATSATSHTRSLNSIIHQMEKFSSSLHELSSRVEASHLTT 281
Query: 73 DELRTL-MKEQNDQLQDYRVKYLQAQQLVEEQR-RQXXXXXXXNTRISEQINL-EIQRVK 129
+ R L ++++++QL+ + + Q Q+ +EE+R RQ R++EQ L E +R +
Sbjct: 282 SQERELGIRQRDEQLRALQERLGQQQRDMEEERSRQQEVIGKMEARLNEQSRLLEQERWR 341
Query: 130 LKFQ----EKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIF 185
+ + E +Q + A QM ++ A+ +A + EQ + L C E+
Sbjct: 342 VTAEQSKAESMQRALEEQRKVTAQQMAMERAELERAKSALLEEQKSVMLKCGEER----- 396
Query: 186 RYLYSLY--LVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEK 243
R L + + L++E +++ + + + + L + + E +EK
Sbjct: 397 RRLAAEWAEFSAQQKLSKERAEREAERALQVDTQREGTLISLAKQAELKIRASELRAEEK 456
Query: 244 QMALLNQRISQLAENNISLKSEIERLKASVIRTE---ESALANEKRLQEKMHECAQLGGE 300
Q+A +R + L + L+ E ER+ A+ +R + E + K EK E + E
Sbjct: 457 QLAA--ER-AALEQERQELRLEKERINATALRVKLRAEEVESMSKVASEKYEEGERALRE 513
Query: 301 LDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKE 350
+ + E LQ +Q E +RK Q E LA R Q+ A ++
Sbjct: 514 AQQVQAEQQARLQAVQQQQERLRKQEQHMHQE-HLSLAQQRLQLDRARQD 562
Score = 41.1 bits (92), Expect = 0.007
Identities = 77/347 (22%), Positives = 148/347 (42%), Gaps = 41/347 (11%)
Query: 23 TQNKLRELEMKFEGL----ATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTL 78
+Q +L ELE + L A H +L+GS +Q + + ++ ++ +R I L T
Sbjct: 102 SQARLAELEAQVRKLELERAQH-ELLLGSLQQ--QHQADLELIESAHRS---RIKVLETS 155
Query: 79 MKEQNDQL----QDYRVKYLQAQQLVEEQRRQXXXXXXXN-TRISEQINLEIQRVKLKFQ 133
+++ ++L ++ +YL Q E+ R + I+++ + E++R++
Sbjct: 156 YQQREERLRRENEELSARYLSQCQEAEQARAELTAQHQRRLAAIAQEKDQEMERLR---- 211
Query: 134 EKLQELAPIPDLLKATQ---MRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYS 190
+LQ A I D+ + + RLK + + A +A R LN ++H S
Sbjct: 212 -ELQR-ASILDMRRDHEEQLQRLKLLKDREVDAATSATSHTRSLN----SIIHQMEKFSS 265
Query: 191 LYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQ 250
+ + L + E+G +D+ + L L ++ E +Q ++ +
Sbjct: 266 SLHELSSRVEASHLTTSQERELGIRQRDEQLRAL-QERLGQQQRDMEEERS-RQQEVIGK 323
Query: 251 RISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASR 310
++L E + L+ E R+ A + E A E++ + + A EL+R + S
Sbjct: 324 MEARLNEQSRLLEQERWRVTAEQSKAESMQRALEEQRKVTAQQMAMERAELERAK---SA 380
Query: 311 ALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNR 357
L+ EQ + KC E R+LAA A+ S +K +E R
Sbjct: 381 LLE---EQKSVMLKC-----GEERRRLAAEWAEFSAQQKLSKERAER 419
Score = 34.7 bits (76), Expect = 0.60
Identities = 39/128 (30%), Positives = 64/128 (50%), Gaps = 17/128 (13%)
Query: 241 DEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALAN----EKRLQEKMHE-CA 295
+ Q AL QR A+ ++E+ER K++++ ++S + +RL + E A
Sbjct: 350 ESMQRALEEQR-KVTAQQMAMERAELERAKSALLEEQKSVMLKCGEERRRLAAEWAEFSA 408
Query: 296 QLGGELDRTRDEASRALQRAHEQTETVRKC-----LQTTVAEL---ERQLAASRAQVSTA 347
Q +R EA RALQ ++ T+ L+ +EL E+QLAA RA +
Sbjct: 409 QQKLSKERAEREAERALQVDTQREGTLISLAKQAELKIRASELRAEEKQLAAERAAL--- 465
Query: 348 EKEREELK 355
E+ER+EL+
Sbjct: 466 EQERQELR 473
>AY518538-1|AAT44534.1| 1179|Homo sapiens rhabdomyosarcoma antigen
MU-RMS-40.7B protein.
Length = 1179
Score = 45.6 bits (103), Expect = 3e-04
Identities = 62/313 (19%), Positives = 132/313 (42%), Gaps = 20/313 (6%)
Query: 61 LKQCYREAREEIDELRTLMKEQNDQLQDYRVKY----LQAQQLVEEQRRQXXXXXXXNTR 116
L++ Y E E EL+ ++ + N ++ +R KY +Q + +EE +++
Sbjct: 587 LREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEE 646
Query: 117 ISEQINLE---IQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQ--AQAIAE--HNAEQ 169
E +N + +++ K + Q ++++L + A L Q+ + +AE E+
Sbjct: 647 AVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEE 706
Query: 170 LARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHV-LLHNS 228
EL ++++ + L+ L +L + F + + D T + +
Sbjct: 707 SQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKT 766
Query: 229 LKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQ 288
+ EK ++ EK + S L E SL+ E ++ + + + E++L
Sbjct: 767 IHELEKVRKQLEAEKM-----ELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLA 821
Query: 289 EKMHECAQLGGELDRTRDEASRALQ---RAHEQTETVRKCLQTTVAELERQLAASRAQVS 345
EK E Q R D +L R+ + V+K ++ + E+E QL+ + +
Sbjct: 822 EKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAA 881
Query: 346 TAEKEREELKNRL 358
A+K+ + L++ L
Sbjct: 882 EAQKQVKSLQSLL 894
Score = 41.1 bits (92), Expect = 0.007
Identities = 55/339 (16%), Positives = 137/339 (40%), Gaps = 13/339 (3%)
Query: 67 EAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQ 126
+ ++++ EL+ ++E ++L+ R + ++L + R+ +++I+
Sbjct: 347 QLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIE 406
Query: 127 RVKLK---FQEKLQEL--APIPDLLKATQMRLKDAQQAQAIAEH--NAEQLARELNCARE 179
K + FQ+ ++L A + A +R K A + E N +++ ++L +
Sbjct: 407 MNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKS 466
Query: 180 KV-VHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIG--RGNKDQTVHVLLHNSLKPPEKPP 236
+ + + ++ + E + + ++ R ++T + + + +
Sbjct: 467 EFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQQAKLQT 526
Query: 237 ERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQ 296
E G +Q+ ISQL ++ ++E LK + ++ A LQ H+C
Sbjct: 527 ENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDL 586
Query: 297 LGGELD---RTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREE 353
L + + + E R L +A+ + R +T + +L ++ +++ +E EE
Sbjct: 587 LREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEE 646
Query: 354 LKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRRTASS 392
++ + L + + Q I L V+ A++
Sbjct: 647 AVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAA 685
Score = 39.5 bits (88), Expect = 0.021
Identities = 76/386 (19%), Positives = 157/386 (40%), Gaps = 47/386 (12%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTL 78
++ E+Q++L + + L+T L + E++ E ++ K+ + +EEI +L
Sbjct: 703 KYEESQSELESSQKEARSLSTELFKLKNAYEESLE---HLETFKRENKNLQEEISDLTEQ 759
Query: 79 MKEQNDQLQDYRV--KYLQAQQL-VEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEK 135
+ + + K L+A+++ ++ + + LE ++K + + K
Sbjct: 760 LGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERK 819
Query: 136 LQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVT 195
L E + K +R+ D+ Q AE + A + E ++ L
Sbjct: 820 LAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEI--QLSHAN 877
Query: 196 TMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQL 255
M + QS + KD + L +++ R D+ L + I+ +
Sbjct: 878 RMAAEAQKQVKSLQSLL----KDTQIQ--LDDAV--------RANDD-----LKENIAIV 918
Query: 256 AENNISLKSEIERLKASVIRTEESALANEKRLQEK--------------MHECAQLGGEL 301
N L++E+E L+A V +TE S E+ L E +++ ++ +L
Sbjct: 919 ERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADL 978
Query: 302 DRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQ 361
+ + E A+Q E +K + T A + +L + Q ++A ER +K +
Sbjct: 979 SQLQTEVEEAVQECRNAEEKAKKAI-TDAAMMAEEL--KKEQDTSAHLER--MKKNMEQT 1033
Query: 362 MKRLTENFEQA-QLRILGLQTQVQSL 386
+K L ++A Q+ + G + Q+Q L
Sbjct: 1034 IKDLQHRLDEAEQIALKGGKKQLQKL 1059
Score = 38.7 bits (86), Expect = 0.037
Identities = 75/374 (20%), Positives = 151/374 (40%), Gaps = 30/374 (8%)
Query: 22 ETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQC-YREAREEIDELRTLMK 80
+T ++L ++ + E + E + E E Q + + + EI+
Sbjct: 765 KTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKD 824
Query: 81 EQNDQLQDYRVKYLQAQQL-VEEQRRQXXXXXXXNTRISEQIN-LEIQ--RVKLKFQEKL 136
E+ +Q + ++ + + Q ++ + R ++ +N +EIQ E
Sbjct: 825 EEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQ 884
Query: 137 QELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTT 196
+++ + LLK TQ++L DA +A + N + R N + + L L V
Sbjct: 885 KQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAE-------LEELRAVVE 937
Query: 197 MTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLA 256
T L Q I + Q +H + SL +K + + Q + + + +
Sbjct: 938 QTERSRKL--AEQELIETSERVQLLH-SQNTSLINQKKKMDADLSQLQTE-VEEAVQECR 993
Query: 257 ENNISLKSEI--ERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASR-ALQ 313
K I + A ++ E+ A+ +R+++ M + + +L DEA + AL+
Sbjct: 994 NAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIK---DLQHRLDEAEQIALK 1050
Query: 314 RAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQ 373
+Q + L+ V ELE +L A + + + + K + + R+ K LT E+ +
Sbjct: 1051 GGKKQLQK----LEARVRELENELEAEQKRNAESVKGMRKSERRI----KELTYQTEEDR 1102
Query: 374 LRILGLQTQVQSLR 387
+L LQ V L+
Sbjct: 1103 KNLLRLQDLVDKLQ 1116
Score = 34.3 bits (75), Expect = 0.80
Identities = 67/322 (20%), Positives = 128/322 (39%), Gaps = 23/322 (7%)
Query: 48 KEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQX 107
KE + E + L++ +E ++L+ ++ + D L D + QL++ + +
Sbjct: 104 KEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEER---CDQLIKNKIQLE 160
Query: 108 XXXXXXNTRIS--EQINLEIQRVKLKFQEKLQELA-PIPDL----------LKATQMRLK 154
N R+ E++N E+ K K +++ EL I DL AT+ ++K
Sbjct: 161 AKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVK 220
Query: 155 DAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLY-LVTTMTLTQEDLFGQSQSEIG 213
+ + A + +L +E +E L + V T+T + L Q G
Sbjct: 221 NLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEG 280
Query: 214 RGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASV 273
+++ V + L + + E + E M L N + QL E E+ L A +
Sbjct: 281 SLEQEKKVRMDLERAKRKLEGDLKLT-QESIMDLENDK-QQLDERLKKKDFELNALNARI 338
Query: 274 IRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAEL 333
+E AL ++ LQ+K+ E EL+ + A + + + + L+ L
Sbjct: 339 --EDEQALGSQ--LQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERL 394
Query: 334 ERQLAASRAQVSTAEKEREELK 355
E A+ Q+ +K E +
Sbjct: 395 EEAGGATSVQIEMNKKREAEFQ 416
Score = 31.9 bits (69), Expect = 4.3
Identities = 38/157 (24%), Positives = 71/157 (45%), Gaps = 22/157 (14%)
Query: 225 LHNSLKPPEKPPERGGDEKQMALLNQ---RISQLAENNISLKSEIERLKASV-------- 273
L+ +KP K ER EK+MA + + R+ + E + + + E+E S+
Sbjct: 76 LYFKIKPLLKSAER---EKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQ 132
Query: 274 --IRTEESALAN-EKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTV 330
++ E+ LA+ E+R + + QL ++ + + E T RK L+
Sbjct: 133 LQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRK-LEDEC 191
Query: 331 AELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTE 367
+EL+R + ++ EKE+ +N+ +K LTE
Sbjct: 192 SELKRDIDDLELTLAKVEKEKHATENK----VKNLTE 224
>AL136382-1|CAI23513.1| 620|Homo sapiens novel protein protein.
Length = 620
Score = 45.6 bits (103), Expect = 3e-04
Identities = 58/264 (21%), Positives = 112/264 (42%), Gaps = 27/264 (10%)
Query: 55 EVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXN 114
+ + ALK E+ EL+ + K+Q ++ Y+ + + Q+ E + + N
Sbjct: 352 KTTLAALKDEVVSVENELSELQEVEKKQKTLIEMYKTQVQKLQEAAEIVKSRCENLLHKN 411
Query: 115 TRISEQINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQ-------AIAEHNA 167
+I++ N +++++ + + L+EL + D L A + RL + Q++ A EH
Sbjct: 412 NQITKTKNKNVEKMRGQMESHLKELERVCDSLTAAERRLHECQESLQCCKGKCADQEHTI 471
Query: 168 EQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSE--------IGRGNKD- 218
+L ++ E+ + + L+T ++L +E+ Q + E + NK+
Sbjct: 472 RELQGQILKQWEEYSVLAWVDGNHNLLTKLSLEEENCLIQLKCENLQQKLEQMDAENKEL 531
Query: 219 -----QTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASV 273
L H++LK EK E AL Q + L E + EIE++ +
Sbjct: 532 EKKLANQEECLKHSNLKFKEKSAE------YTALARQLEAALEEGRQKVAEEIEKMSSRE 585
Query: 274 IRTEESALANEKRLQEKMHECAQL 297
+ L E L++K E QL
Sbjct: 586 SALQIKILDLETELRKKNEEQNQL 609
>AJ238393-1|CAC20413.1| 1935|Homo sapiens beta-myosin heavy chain
protein.
Length = 1935
Score = 45.6 bits (103), Expect = 3e-04
Identities = 62/313 (19%), Positives = 132/313 (42%), Gaps = 20/313 (6%)
Query: 61 LKQCYREAREEIDELRTLMKEQNDQLQDYRVKY----LQAQQLVEEQRRQXXXXXXXNTR 116
L++ Y E E EL+ ++ + N ++ +R KY +Q + +EE +++
Sbjct: 1343 LREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEE 1402
Query: 117 ISEQINLE---IQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQ--AQAIAE--HNAEQ 169
E +N + +++ K + Q ++++L + A L Q+ + +AE E+
Sbjct: 1403 AVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEE 1462
Query: 170 LARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHV-LLHNS 228
EL ++++ + L+ L +L + F + + D T + +
Sbjct: 1463 SQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKT 1522
Query: 229 LKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQ 288
+ EK ++ EK + S L E SL+ E ++ + + + E++L
Sbjct: 1523 IHELEKVRKQLEAEKM-----ELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLA 1577
Query: 289 EKMHECAQLGGELDRTRDEASRALQ---RAHEQTETVRKCLQTTVAELERQLAASRAQVS 345
EK E Q R D +L R+ + V+K ++ + E+E QL+ + +
Sbjct: 1578 EKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAA 1637
Query: 346 TAEKEREELKNRL 358
A+K+ + L++ L
Sbjct: 1638 EAQKQVKSLQSLL 1650
Score = 39.9 bits (89), Expect = 0.016
Identities = 55/339 (16%), Positives = 136/339 (40%), Gaps = 13/339 (3%)
Query: 67 EAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQ 126
+ ++++ EL+ ++E ++L+ R + ++L + R+ + +I+
Sbjct: 1103 QLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSCQIE 1162
Query: 127 RVKLK---FQEKLQEL--APIPDLLKATQMRLKDAQQAQAIAEH--NAEQLARELNCARE 179
K + FQ+ ++L A + A +R K A + E N +++ ++L +
Sbjct: 1163 MNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKS 1222
Query: 180 KV-VHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIG--RGNKDQTVHVLLHNSLKPPEKPP 236
+ + + ++ + E + + ++ R ++T + + + +
Sbjct: 1223 EFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQT 1282
Query: 237 ERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQ 296
E G +Q+ ISQL ++ ++E LK + ++ A LQ H+C
Sbjct: 1283 ENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDL 1342
Query: 297 LGGELD---RTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREE 353
L + + + E R L +A+ + R +T + +L ++ +++ +E EE
Sbjct: 1343 LREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEE 1402
Query: 354 LKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRRTASS 392
++ + L + + Q I L V+ A++
Sbjct: 1403 AVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAA 1441
Score = 39.5 bits (88), Expect = 0.021
Identities = 76/386 (19%), Positives = 157/386 (40%), Gaps = 47/386 (12%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTL 78
++ E+Q++L + + L+T L + E++ E ++ K+ + +EEI +L
Sbjct: 1459 KYEESQSELESSQKEARSLSTELFKLKNAYEESLE---HLETFKRENKNLQEEISDLTEQ 1515
Query: 79 MKEQNDQLQDYRV--KYLQAQQL-VEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEK 135
+ + + K L+A+++ ++ + + LE ++K + + K
Sbjct: 1516 LGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERK 1575
Query: 136 LQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVT 195
L E + K +R+ D+ Q AE + A + E ++ L
Sbjct: 1576 LAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEI--QLSHAN 1633
Query: 196 TMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQL 255
M + QS + KD + L +++ R D+ L + I+ +
Sbjct: 1634 RMAAEAQKQVKSLQSLL----KDTQIQ--LDDAV--------RANDD-----LKENIAIV 1674
Query: 256 AENNISLKSEIERLKASVIRTEESALANEKRLQEK--------------MHECAQLGGEL 301
N L++E+E L+A V +TE S E+ L E +++ ++ +L
Sbjct: 1675 ERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADL 1734
Query: 302 DRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQ 361
+ + E A+Q E +K + T A + +L + Q ++A ER +K +
Sbjct: 1735 SQLQTEVEEAVQECRNAEEKAKKAI-TDAAMMAEEL--KKEQDTSAHLER--MKKNMEQT 1789
Query: 362 MKRLTENFEQA-QLRILGLQTQVQSL 386
+K L ++A Q+ + G + Q+Q L
Sbjct: 1790 IKDLQHRLDEAEQIALKGGKKQLQKL 1815
Score = 38.7 bits (86), Expect = 0.037
Identities = 75/374 (20%), Positives = 151/374 (40%), Gaps = 30/374 (8%)
Query: 22 ETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQC-YREAREEIDELRTLMK 80
+T ++L ++ + E + E + E E Q + + + EI+
Sbjct: 1521 KTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKD 1580
Query: 81 EQNDQLQDYRVKYLQAQQL-VEEQRRQXXXXXXXNTRISEQIN-LEIQ--RVKLKFQEKL 136
E+ +Q + ++ + + Q ++ + R ++ +N +EIQ E
Sbjct: 1581 EEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQ 1640
Query: 137 QELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTT 196
+++ + LLK TQ++L DA +A + N + R N + + L L V
Sbjct: 1641 KQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAE-------LEELRAVVE 1693
Query: 197 MTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLA 256
T L Q I + Q +H + SL +K + + Q + + + +
Sbjct: 1694 QTERSRKL--AEQELIETSERVQLLH-SQNTSLINQKKKMDADLSQLQTE-VEEAVQECR 1749
Query: 257 ENNISLKSEI--ERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASR-ALQ 313
K I + A ++ E+ A+ +R+++ M + + +L DEA + AL+
Sbjct: 1750 NAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIK---DLQHRLDEAEQIALK 1806
Query: 314 RAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQ 373
+Q + L+ V ELE +L A + + + + K + + R+ K LT E+ +
Sbjct: 1807 GGKKQLQK----LEARVRELENELEAEQKRNAESVKGMRKSERRI----KELTYQTEEDR 1858
Query: 374 LRILGLQTQVQSLR 387
+L LQ V L+
Sbjct: 1859 KNLLRLQDLVDKLQ 1872
Score = 34.3 bits (75), Expect = 0.80
Identities = 67/322 (20%), Positives = 128/322 (39%), Gaps = 23/322 (7%)
Query: 48 KEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQX 107
KE + E + L++ +E ++L+ ++ + D L D + QL++ + +
Sbjct: 860 KEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEER---CDQLIKNKIQLE 916
Query: 108 XXXXXXNTRIS--EQINLEIQRVKLKFQEKLQELA-PIPDL----------LKATQMRLK 154
N R+ E++N E+ K K +++ EL I DL AT+ ++K
Sbjct: 917 AKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVK 976
Query: 155 DAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLY-LVTTMTLTQEDLFGQSQSEIG 213
+ + A + +L +E +E L + V T+T + L Q G
Sbjct: 977 NLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEG 1036
Query: 214 RGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASV 273
+++ V + L + + E + E M L N + QL E E+ L A +
Sbjct: 1037 SLEQEKKVRMDLERAKRKLEGDLKLT-QESIMDLENDK-QQLDERLKKKDFELNALNARI 1094
Query: 274 IRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAEL 333
+E AL ++ LQ+K+ E EL+ + A + + + + L+ L
Sbjct: 1095 --EDEQALGSQ--LQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERL 1150
Query: 334 ERQLAASRAQVSTAEKEREELK 355
E A+ Q+ +K E +
Sbjct: 1151 EEAGGATSCQIEMNKKREAEFQ 1172
Score = 31.9 bits (69), Expect = 4.3
Identities = 38/157 (24%), Positives = 71/157 (45%), Gaps = 22/157 (14%)
Query: 225 LHNSLKPPEKPPERGGDEKQMALLNQ---RISQLAENNISLKSEIERLKASV-------- 273
L+ +KP K ER EK+MA + + R+ + E + + + E+E S+
Sbjct: 832 LYFKIKPLLKSAER---EKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQ 888
Query: 274 --IRTEESALAN-EKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTV 330
++ E+ LA+ E+R + + QL ++ + + E T RK L+
Sbjct: 889 LQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRK-LEDEC 947
Query: 331 AELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTE 367
+EL+R + ++ EKE+ +N+ +K LTE
Sbjct: 948 SELKRDIDDLELTLAKVEKEKHATENK----VKNLTE 980
>AF112218-1|AAF17206.1| 742|Homo sapiens unknown protein.
Length = 742
Score = 45.6 bits (103), Expect = 3e-04
Identities = 59/333 (17%), Positives = 145/333 (43%), Gaps = 23/333 (6%)
Query: 42 NMLMGSKEQAFEQEV--NVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQL 99
N + K + E E+ ++L+ C +++ + E + +++ + L++ + ++ +
Sbjct: 425 NQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKE-KAQLEKTIETLRENSERQIKILEQ 483
Query: 100 VEEQRRQXXXXXXXNTRISEQINL-EIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQ 158
E Q ++IS + + +I++ E ++E + ++ + ++K +
Sbjct: 484 ENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELE 543
Query: 159 AQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKD 218
AE+L EL+ ++ + + + +L + T + + Q SE+ R N+
Sbjct: 544 HYKEKGERAEELENELHHLEKENELLQKKITNLKI----TCEKIEALEQENSELERENRK 599
Query: 219 QTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEE 278
+ +L Q+ L + SQL E N+ L+ +E LK + ++ +
Sbjct: 600 LKKTLDSFKNLT------------FQLESLEKENSQLDEENLELRRNVESLKCASMKMAQ 647
Query: 279 SALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLA 338
L N++ EK E + G EL + + + L+ +++ + + LQ T+ +++
Sbjct: 648 LQLENKELESEK--EQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQ 705
Query: 339 ASRAQVSTAEKEREELKNRLHWQMKRLTENFEQ 371
+++ E E + L+ L ++K ++ EQ
Sbjct: 706 QLESELQDLEMENQTLQKNLE-ELKISSKRLEQ 737
>AB209708-1|BAD92945.1| 1574|Homo sapiens myosin, heavy polypeptide 7,
cardiac muscle, beta variant protein.
Length = 1574
Score = 45.6 bits (103), Expect = 3e-04
Identities = 62/313 (19%), Positives = 132/313 (42%), Gaps = 20/313 (6%)
Query: 61 LKQCYREAREEIDELRTLMKEQNDQLQDYRVKY----LQAQQLVEEQRRQXXXXXXXNTR 116
L++ Y E E EL+ ++ + N ++ +R KY +Q + +EE +++
Sbjct: 982 LREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEE 1041
Query: 117 ISEQINLE---IQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQ--AQAIAE--HNAEQ 169
E +N + +++ K + Q ++++L + A L Q+ + +AE E+
Sbjct: 1042 AVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEE 1101
Query: 170 LARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHV-LLHNS 228
EL ++++ + L+ L +L + F + + D T + +
Sbjct: 1102 SQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKT 1161
Query: 229 LKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQ 288
+ EK ++ EK + S L E SL+ E ++ + + + E++L
Sbjct: 1162 IHELEKVRKQLEAEKM-----ELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLA 1216
Query: 289 EKMHECAQLGGELDRTRDEASRALQ---RAHEQTETVRKCLQTTVAELERQLAASRAQVS 345
EK E Q R D +L R+ + V+K ++ + E+E QL+ + +
Sbjct: 1217 EKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAA 1276
Query: 346 TAEKEREELKNRL 358
A+K+ + L++ L
Sbjct: 1277 EAQKQVKSLQSLL 1289
Score = 40.7 bits (91), Expect = 0.009
Identities = 55/339 (16%), Positives = 137/339 (40%), Gaps = 13/339 (3%)
Query: 67 EAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQ 126
+ ++++ EL+ ++E ++L+ R + ++L + R+ +++I+
Sbjct: 742 QLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIE 801
Query: 127 RVKLK---FQEKLQEL--APIPDLLKATQMRLKDAQQAQAIAEH--NAEQLARELNCARE 179
K + FQ+ ++L A + A +R K A + E N +++ ++L +
Sbjct: 802 MNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKS 861
Query: 180 KV-VHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIG--RGNKDQTVHVLLHNSLKPPEKPP 236
+ + + ++ + E + + ++ R ++T + + + +
Sbjct: 862 EFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQT 921
Query: 237 ERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQ 296
E G +Q+ ISQL ++ ++E LK + ++ A LQ H+C
Sbjct: 922 ENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDL 981
Query: 297 LGGELD---RTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREE 353
L + + + E R L +A+ + R +T + +L ++ +++ +E EE
Sbjct: 982 LREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEE 1041
Query: 354 LKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRRTASS 392
++ + L + + Q I L V+ A++
Sbjct: 1042 AVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAA 1080
Score = 39.5 bits (88), Expect = 0.021
Identities = 76/386 (19%), Positives = 157/386 (40%), Gaps = 47/386 (12%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTL 78
++ E+Q++L + + L+T L + E++ E ++ K+ + +EEI +L
Sbjct: 1098 KYEESQSELESSQKEARSLSTELFKLKNAYEESLE---HLETFKRENKNLQEEISDLTEQ 1154
Query: 79 MKEQNDQLQDYRV--KYLQAQQL-VEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEK 135
+ + + K L+A+++ ++ + + LE ++K + + K
Sbjct: 1155 LGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERK 1214
Query: 136 LQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVT 195
L E + K +R+ D+ Q AE + A + E ++ L
Sbjct: 1215 LAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEI--QLSHAN 1272
Query: 196 TMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQL 255
M + QS + KD + L +++ R D+ L + I+ +
Sbjct: 1273 RMAAEAQKQVKSLQSLL----KDTQIQ--LDDAV--------RANDD-----LKENIAIV 1313
Query: 256 AENNISLKSEIERLKASVIRTEESALANEKRLQEK--------------MHECAQLGGEL 301
N L++E+E L+A V +TE S E+ L E +++ ++ +L
Sbjct: 1314 ERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADL 1373
Query: 302 DRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQ 361
+ + E A+Q E +K + T A + +L + Q ++A ER +K +
Sbjct: 1374 SQLQTEVEEAVQECRNAEEKAKKAI-TDAAMMAEEL--KKEQDTSAHLER--MKKNMEQT 1428
Query: 362 MKRLTENFEQA-QLRILGLQTQVQSL 386
+K L ++A Q+ + G + Q+Q L
Sbjct: 1429 IKDLQHRLDEAEQIALKGGKKQLQKL 1454
Score = 38.7 bits (86), Expect = 0.037
Identities = 75/374 (20%), Positives = 151/374 (40%), Gaps = 30/374 (8%)
Query: 22 ETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQC-YREAREEIDELRTLMK 80
+T ++L ++ + E + E + E E Q + + + EI+
Sbjct: 1160 KTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKD 1219
Query: 81 EQNDQLQDYRVKYLQAQQL-VEEQRRQXXXXXXXNTRISEQIN-LEIQ--RVKLKFQEKL 136
E+ +Q + ++ + + Q ++ + R ++ +N +EIQ E
Sbjct: 1220 EEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQ 1279
Query: 137 QELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTT 196
+++ + LLK TQ++L DA +A + N + R N + + L L V
Sbjct: 1280 KQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAE-------LEELRAVVE 1332
Query: 197 MTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLA 256
T L Q I + Q +H + SL +K + + Q + + + +
Sbjct: 1333 QTERSRKL--AEQELIETSERVQLLH-SQNTSLINQKKKMDADLSQLQTE-VEEAVQECR 1388
Query: 257 ENNISLKSEI--ERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASR-ALQ 313
K I + A ++ E+ A+ +R+++ M + + +L DEA + AL+
Sbjct: 1389 NAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIK---DLQHRLDEAEQIALK 1445
Query: 314 RAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQ 373
+Q + L+ V ELE +L A + + + + K + + R+ K LT E+ +
Sbjct: 1446 GGKKQLQK----LEARVRELENELEAEQKRNAESVKGMRKSERRI----KELTYQTEEDR 1497
Query: 374 LRILGLQTQVQSLR 387
+L LQ V L+
Sbjct: 1498 KNLLRLQDLVDKLQ 1511
Score = 34.3 bits (75), Expect = 0.80
Identities = 67/322 (20%), Positives = 128/322 (39%), Gaps = 23/322 (7%)
Query: 48 KEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQX 107
KE + E + L++ +E ++L+ ++ + D L D + QL++ + +
Sbjct: 499 KEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEER---CDQLIKNKIQLE 555
Query: 108 XXXXXXNTRIS--EQINLEIQRVKLKFQEKLQELA-PIPDL----------LKATQMRLK 154
N R+ E++N E+ K K +++ EL I DL AT+ ++K
Sbjct: 556 AKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVK 615
Query: 155 DAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLY-LVTTMTLTQEDLFGQSQSEIG 213
+ + A + +L +E +E L + V T+T + L Q G
Sbjct: 616 NLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEG 675
Query: 214 RGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASV 273
+++ V + L + + E + E M L N + QL E E+ L A +
Sbjct: 676 SLEQEKKVRMDLERAKRKLEGDLKLT-QESIMDLENDK-QQLDERLKKKDFELNALNARI 733
Query: 274 IRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAEL 333
+E AL ++ LQ+K+ E EL+ + A + + + + L+ L
Sbjct: 734 --EDEQALGSQ--LQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERL 789
Query: 334 ERQLAASRAQVSTAEKEREELK 355
E A+ Q+ +K E +
Sbjct: 790 EEAGGATSVQIEMNKKREAEFQ 811
Score = 31.9 bits (69), Expect = 4.3
Identities = 38/157 (24%), Positives = 71/157 (45%), Gaps = 22/157 (14%)
Query: 225 LHNSLKPPEKPPERGGDEKQMALLNQ---RISQLAENNISLKSEIERLKASV-------- 273
L+ +KP K ER EK+MA + + R+ + E + + + E+E S+
Sbjct: 471 LYFKIKPLLKSAER---EKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQ 527
Query: 274 --IRTEESALAN-EKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTV 330
++ E+ LA+ E+R + + QL ++ + + E T RK L+
Sbjct: 528 LQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRK-LEDEC 586
Query: 331 AELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTE 367
+EL+R + ++ EKE+ +N+ +K LTE
Sbjct: 587 SELKRDIDDLELTLAKVEKEKHATENK----VKNLTE 619
>M36769-1|AAC17185.1| 1937|Homo sapiens perinatal myosin heavy chain
protein.
Length = 1937
Score = 45.2 bits (102), Expect = 4e-04
Identities = 80/397 (20%), Positives = 163/397 (41%), Gaps = 38/397 (9%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTL 78
++ ETQ +L + + L+T + E++ +Q + L++ ++ ++EI +L
Sbjct: 1462 KYEETQAELEASQKESRSLSTELFKVKNVYEESLDQ---LETLRRAHKNLQQEISDLTEQ 1518
Query: 79 MKEQNDQLQDY-RVKYLQAQQLVEEQRRQXXXXXXXNTRISE--QINLEIQRVKLKFQEK 135
+ E Q+ + ++K Q+ E Q + +I LE+ +VK + K
Sbjct: 1519 IAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRK 1578
Query: 136 LQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVT 195
+ E D LK R+ + Q+ AE + A + E ++ + L
Sbjct: 1579 IAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEME----IQLNH 1634
Query: 196 TMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQL 255
L E L ++ G +T + L ++L+ E E Q+A++ +R + L
Sbjct: 1635 ANRLAAESLRNYRNTQ---GILKET-QLHLDDALRGQEDLKE------QLAIVERRANLL 1684
Query: 256 AENNISLKSEIERLKASVIRTEESALANEKRL---QEKMHECAQLGGELDRTRDEASRAL 312
++EIE L A++ +TE S E+ L E++ L T+ + +
Sbjct: 1685 -------QAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDV 1737
Query: 313 QRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKER------EELKNRLHWQMKRLT 366
+ + E V + + + ++ + + +KE+ E +K L +K L
Sbjct: 1738 SQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQ 1797
Query: 367 ENFEQA-QLRILGLQTQVQSLRRTASSTGDGDGENQE 402
++A QL + G + Q+Q L +G+ EN++
Sbjct: 1798 HRLDEAEQLALKGGKKQIQKLEARVREL-EGEVENEQ 1833
Score = 39.9 bits (89), Expect = 0.016
Identities = 70/369 (18%), Positives = 146/369 (39%), Gaps = 15/369 (4%)
Query: 24 QNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQN 83
Q ++LE + L T+ L + E + + ++ K C R +++ L+T +EQ
Sbjct: 1214 QRVKQKLEKEKSELKMETDDLSSNAEAISKAKGHLE--KMC-RSLEDQVSGLKTKEEEQQ 1270
Query: 84 DQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIP 143
+ D + + Q E RQ +++S Q+++ + + +L+E
Sbjct: 1271 RLINDLTAQRARLQTEAGEYSRQLDEQDALVSQLSRSKQASTQQIE-ELKHQLEEETKAK 1329
Query: 144 D-LLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQE 202
+ L A Q D + E E A EL A K + Y + T+E
Sbjct: 1330 NALAHALQSSRHDCDLLREQYEEEQEGKA-ELQRALSKANSEVAQWRTKYETDAIQRTEE 1388
Query: 203 DLFGQSQSEIGRGNKDQTVHVLLHNS-LKPPEKPPERGGDEKQMALLNQRISQLAENNIS 261
+++ ++ + ++ HV N+ EK +R +E + +L+ S A +
Sbjct: 1389 --LEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAA--CAA 1444
Query: 262 LKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTET 321
L + + ++ + L+ E L EL + ++ +L + E
Sbjct: 1445 LDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQL-ETLRR 1503
Query: 322 VRKCLQTTVAELERQLAASRAQVSTAE---KEREELKNRLHWQMKRLTENFEQAQLRILG 378
K LQ +++L Q+A Q+ E K+ E+ K + ++ + E + +IL
Sbjct: 1504 AHKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILR 1563
Query: 379 LQTQVQSLR 387
+Q ++ ++
Sbjct: 1564 IQLELNQVK 1572
Score = 33.9 bits (74), Expect = 1.1
Identities = 70/329 (21%), Positives = 131/329 (39%), Gaps = 31/329 (9%)
Query: 49 EQAFEQEVNVRA-LKQCYREAREEID---ELRTLMKEQNDQLQDYRVKYLQAQQLVEEQR 104
EQ + ++ + A +K+ A EE + EL ++ D+ + + + + +
Sbjct: 909 EQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 968
Query: 105 RQXXXXXXXNTRISEQI-NLEIQRVKLKFQEK-LQEL-APIPDLLKATQMRLKDAQQAQA 161
+Q ++E++ L+ KL ++K LQE D L+A + ++ +A+
Sbjct: 969 KQKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNILTKAKT 1028
Query: 162 IAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTV 221
E + L L +EK + + L + L QE + K +
Sbjct: 1029 KLEQQVDDLEGSLE--QEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKK 1086
Query: 222 HVLLHNSLKPPEKPPERGGDEKQMAL-LNQRISQLAENNISLKSEIERLKASVIRTEESA 280
+ N + E DE+ + + L ++I +L L EIE +AS + E+
Sbjct: 1087 EFEISNLISKIE-------DEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQR 1139
Query: 281 LANEKRLQEKMHECAQLGG------ELDRTRDEASRALQR-------AHE-QTETVRKCL 326
+ L+E + GG EL++ R+ + L+R HE +RK
Sbjct: 1140 SDLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKH 1199
Query: 327 QTTVAELERQLAASRAQVSTAEKEREELK 355
++AEL Q+ + EKE+ ELK
Sbjct: 1200 ADSMAELGEQIDNLQRVKQKLEKEKSELK 1228
Score = 33.5 bits (73), Expect = 1.4
Identities = 63/313 (20%), Positives = 134/313 (42%), Gaps = 39/313 (12%)
Query: 61 LKQCYREAREEIDELRTLMKEQNDQLQDYRVKY----LQAQQLVEEQRRQXXXXXXXNTR 116
L++ Y E +E EL+ + + N ++ +R KY +Q + +EE +++
Sbjct: 1346 LREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEE 1405
Query: 117 ISEQINLE---IQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQ--AQAIAE--HNAEQ 169
E +N + +++ K + Q ++++L + A L Q+ + ++E E+
Sbjct: 1406 HVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEE 1465
Query: 170 LARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSL 229
EL ++++ + L+ + V +L Q + ++ + + D T +
Sbjct: 1466 TQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRAHKNLQQEISDLTEQI------ 1519
Query: 230 KPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQE 289
GG KQ+ L + Q+ + +++ +E +AS+ E L R+Q
Sbjct: 1520 -------AEGG--KQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKIL----RIQL 1566
Query: 290 KMHECAQLGGELDR---TRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVST 346
+++ Q+ E+DR +DE L+R H T V T AE+ + A R +
Sbjct: 1567 ELN---QVKSEVDRKIAEKDEEIDQLKRNH--TRVVETMQSTLDAEIRSRNDALRVK-KK 1620
Query: 347 AEKEREELKNRLH 359
E + E++ +L+
Sbjct: 1621 MEGDLNEMEIQLN 1633
>BC130564-1|AAI30565.1| 905|Homo sapiens KIAA1524 protein.
Length = 905
Score = 45.2 bits (102), Expect = 4e-04
Identities = 58/271 (21%), Positives = 117/271 (43%), Gaps = 7/271 (2%)
Query: 94 LQAQQLVEE-QRRQXXXXXXXNTRISEQINL-EIQRVKLKFQE-KLQELAPIPDLLKATQ 150
L ++L+E+ Q + RIS+ +++ E++ L +E +LQ+L L A
Sbjct: 595 LNIEELIEKLQSGMVVKDQICDVRISDIMDVYEMKLSTLASKESRLQDLLETKALALAQA 654
Query: 151 MRLKDAQQAQAI-AEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQ 209
RL + Q AE A LA L K + L + + + + + Q
Sbjct: 655 DRLIAQHRCQRTQAETEARTLASMLREVERKNEELSVLLKAQQVESERAQSDIEHLFQHN 714
Query: 210 SEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMAL--LNQRISQLAENNISLKSEIE 267
++ ++ + + L + E+ + Q+ LN++I + + N SLK + E
Sbjct: 715 RKLESVAEEHEILTKSYMELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNESLKEQNE 774
Query: 268 RLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQ 327
+ A +I EE + +L ++ H+ A L + + ++E + LQ+ E E L+
Sbjct: 775 KSIAQLIEKEEQRKEVQNQLVDREHKLANL-HQKTKVQEEKIKTLQKEREDKEETIDILR 833
Query: 328 TTVAELERQLAASRAQVSTAEKEREELKNRL 358
++ E+ + S+ E ++ +L+ RL
Sbjct: 834 KELSRTEQIRKELSIKASSLEVQKAQLEGRL 864
>AL365436-2|CAI16590.1| 1203|Homo sapiens cingulin protein.
Length = 1203
Score = 45.2 bits (102), Expect = 4e-04
Identities = 78/361 (21%), Positives = 156/361 (43%), Gaps = 25/361 (6%)
Query: 21 RETQNKLRELEMKFEG----LATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELR 76
R T+ +L +L M+ E L +L EQA + R ++ +E +EL+
Sbjct: 583 RATKQELLQLRMEKEEMEEELGEKIEVLQRELEQARASAGDTRQVEVLKKELLRTQEELK 642
Query: 77 TLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKL 136
L E+ Q V + +E+Q + EQ NL++Q+ + ++
Sbjct: 643 ELQAERQSQ----EVAGRHRDRELEKQLAVLRVEADRGRELEEQ-NLQLQKTLQQLRQDC 697
Query: 137 QELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLY-LVT 195
+E + + +A L Q +A E + E + R +++ + + L LV
Sbjct: 698 EEASKAKMVAEAEATVL---GQRRAAVETTLRETQEENDEFRRRILGLEQQLKETRGLVD 754
Query: 196 TMTLTQEDLFGQSQS-EIGRGNKDQTVHVLL--HNSLKPPEKPPERGGDEKQMALLNQRI 252
+ L + Q E + ++ ++ SL ++ E +E Q L R+
Sbjct: 755 GGEAVEARLRDKLQRLEAEKQQLEEALNASQEEEGSLAAAKRALEARLEEAQRGL--ARL 812
Query: 253 SQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRAL 312
Q + ++ E E + V+R ++ L +KRL ++ + +L EL++ +++ +AL
Sbjct: 813 GQ-EQQTLNRALEEEGKQREVLRRGKAELEEQKRLLDRTVD--RLNKELEKIGEDSKQAL 869
Query: 313 QRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQA 372
Q+ Q E ++ + VA+ +RQ ++ S AEK L +RL +++RL + + +
Sbjct: 870 QQLQAQLEDYKEKARREVADAQRQ---AKDWASEAEKTSGGL-SRLQDEIQRLRQALQAS 925
Query: 373 Q 373
Q
Sbjct: 926 Q 926
Score = 43.6 bits (98), Expect = 0.001
Identities = 71/368 (19%), Positives = 157/368 (42%), Gaps = 25/368 (6%)
Query: 24 QNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQN 83
++KL+ LE + + L N S+E+ RAL+ EA+ + L + N
Sbjct: 764 RDKLQRLEAEKQQLEEALN---ASQEEEGSLAAAKRALEARLEEAQRGLARLGQEQQTLN 820
Query: 84 DQLQD---YRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQEL- 139
L++ R + + +EEQ+R R +++N E++++ ++ LQ+L
Sbjct: 821 RALEEEGKQREVLRRGKAELEEQKRLLD-------RTVDRLNKELEKIGEDSKQALQQLQ 873
Query: 140 APIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTL 199
A + D + + + DAQ+ AE+ + L+ ++++ + + L +
Sbjct: 874 AQLEDYKEKARREVADAQRQAKDWASEAEKTSGGLSRLQDEIQRLRQALQASQAERDTAR 933
Query: 200 TQEDLFGQ------SQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRIS 253
++L Q ++E + ++D L K E ++ + LL R++
Sbjct: 934 LDKELLAQRLQGLEQEAENKKRSQDDRARQLKGLEEKVSRLETELDEEKNTVELLTDRVN 993
Query: 254 QLAENNISLKSEI--ERLKASVIRTEESALANE-KRLQEKM--HECAQLGGELDRTRDEA 308
+ + L++E+ ER + ++ +L + K L+ ++ E Q +
Sbjct: 994 RGRDQVDQLRTELMQERSARQDLECDKISLERQNKDLKTRLASSEGFQKPSASLSQLESQ 1053
Query: 309 SRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTEN 368
++ LQ + E + LQ+T +LER++ Q+ + + K++L ++K L
Sbjct: 1054 NQLLQERLQAEEREKTVLQSTNRKLERKVKELSIQIEDERQHVNDQKDQLSLRVKALKRQ 1113
Query: 369 FEQAQLRI 376
++A+ I
Sbjct: 1114 VDEAEEEI 1121
Score = 43.2 bits (97), Expect = 0.002
Identities = 71/340 (20%), Positives = 136/340 (40%), Gaps = 20/340 (5%)
Query: 60 ALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISE 119
ALK+ +E++ +R + +QL+ Q ++E +R++ R E
Sbjct: 503 ALKEEVASRDQEVEHVRQQYQRDTEQLRRSMQDATQDHAVLEAERQKMSALVRGLQRELE 562
Query: 120 QINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCARE 179
+ + E + FQ+ ++L L Q+R++ + + + E E L REL AR
Sbjct: 563 ETSEETGHWQSMFQKNKEDLRATKQEL--LQLRMEKEEMEEELGE-KIEVLQRELEQARA 619
Query: 180 KV--VHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPE 237
L L T L + QSQ GR ++D+ L L +
Sbjct: 620 SAGDTRQVEVLKKELLRTQEELKELQAERQSQEVAGR-HRDRE----LEKQLAVLRVEAD 674
Query: 238 RGGD-EKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKR--LQEKMHEC 294
RG + E+Q L + + QL ++ E E KA ++ E+ + ++R ++ + E
Sbjct: 675 RGRELEEQNLQLQKTLQQLRQD-----CE-EASKAKMVAEAEATVLGQRRAAVETTLRET 728
Query: 295 AQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREEL 354
+ E R + L+ + + ++ + + ++L A + Q+ A +E
Sbjct: 729 QEENDEFRRRILGLEQQLKETRGLVDG-GEAVEARLRDKLQRLEAEKQQLEEALNASQEE 787
Query: 355 KNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRRTASSTG 394
+ L + L E+AQ + L + Q+L R G
Sbjct: 788 EGSLAAAKRALEARLEEAQRGLARLGQEQQTLNRALEEEG 827
Score = 41.5 bits (93), Expect = 0.005
Identities = 92/377 (24%), Positives = 148/377 (39%), Gaps = 36/377 (9%)
Query: 28 RELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQ 87
RELE E +M +KE ++RA KQ E+ +LR +E ++L
Sbjct: 559 RELEETSEETGHWQSMFQKNKE-------DLRATKQ-------ELLQLRMEKEEMEEELG 604
Query: 88 DYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELA---PIPD 144
+ +++ LQ + +E+ R E + + + +L+ + + QE+A +
Sbjct: 605 E-KIEVLQRE--LEQARASAGDTRQVEVLKKELLRTQEELKELQAERQSQEVAGRHRDRE 661
Query: 145 LLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDL 204
L K + +A + + + E N QL + L R+ + T+ +
Sbjct: 662 LEKQLAVLRVEADRGRELEEQNL-QLQKTLQQLRQDCEEASKAKMVAEAEATVLGQRRAA 720
Query: 205 FGQSQSEIGRGNKDQTVHVL-LHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLK 263
+ E N + +L L LK E G E A L ++ +L L+
Sbjct: 721 VETTLRETQEENDEFRRRILGLEQQLK--ETRGLVDGGEAVEARLRDKLQRLEAEKQQLE 778
Query: 264 SEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVR 323
E L AS + EE +LA KR E E AQ G L R E + L RA E+ R
Sbjct: 779 ---EALNAS--QEEEGSLAAAKRALEARLEEAQRG--LARLGQE-QQTLNRALEEEGKQR 830
Query: 324 KCLQTTVAELERQLAASRAQVSTAEKEREEL----KNRLHWQMKRLTENFEQAQLRILGL 379
+ L+ AELE Q V KE E++ K L +L + E+A+ +
Sbjct: 831 EVLRRGKAELEEQKRLLDRTVDRLNKELEKIGEDSKQALQQLQAQLEDYKEKARREVADA 890
Query: 380 QTQVQSLRRTASSTGDG 396
Q Q + A T G
Sbjct: 891 QRQAKDWASEAEKTSGG 907
Score = 39.9 bits (89), Expect = 0.016
Identities = 29/104 (27%), Positives = 55/104 (52%), Gaps = 10/104 (9%)
Query: 240 GDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGG 299
G K +A + ++ E L E+++ + + E S + E++L+EK EC++L
Sbjct: 353 GSTKAVAGQGELTRKVEELQRKLDEEVKKRQ----KLEPSQVGLERQLEEKTEECSRLQE 408
Query: 300 ELDRTRDEASRA------LQRAHEQTETVRKCLQTTVAELERQL 337
L+R + EA ++ ++R +Q E +R L+T V EL+ +L
Sbjct: 409 LLERRKGEAQQSNKELQNMKRLLDQGEDLRHGLETQVMELQNKL 452
Score = 39.5 bits (88), Expect = 0.021
Identities = 41/170 (24%), Positives = 74/170 (43%), Gaps = 5/170 (2%)
Query: 223 VLLHNSLKPPEKPPE-RGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESAL 281
VLL + L+ E E G ++ L R +L +LK E+ V +
Sbjct: 464 VLLKDLLETRELLEEVLEGKQRVEEQLRLRERELTALKGALKEEVASRDQEVEHVRQQYQ 523
Query: 282 ANEKRLQEKMHECAQLGGELDRTRDEAS---RALQRAHEQTETVRKCLQTTVAELERQLA 338
+ ++L+ M + Q L+ R + S R LQR E+T Q+ + + L
Sbjct: 524 RDTEQLRRSMQDATQDHAVLEAERQKMSALVRGLQRELEETSEETGHWQSMFQKNKEDLR 583
Query: 339 ASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRR 388
A++ ++ E+EE++ L +++ L EQA+ G QV+ L++
Sbjct: 584 ATKQELLQLRMEKEEMEEELGEKIEVLQRELEQARAS-AGDTRQVEVLKK 632
Score = 34.3 bits (75), Expect = 0.80
Identities = 20/69 (28%), Positives = 38/69 (55%), Gaps = 6/69 (8%)
Query: 20 HRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLM 79
+R+ + K++EL ++ E H N +Q + + V+ALK+ EA EEI+ L L
Sbjct: 1075 NRKLERKVKELSIQIEDERQHVN------DQKDQLSLRVKALKRQVDEAEEEIERLDGLR 1128
Query: 80 KEQNDQLQD 88
K+ ++++
Sbjct: 1129 KKAQREVEE 1137
Score = 31.9 bits (69), Expect = 4.3
Identities = 26/134 (19%), Positives = 56/134 (41%), Gaps = 2/134 (1%)
Query: 21 RETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMK 80
+E +NK R + + L + + + E++ V L R+++D+LRT +
Sbjct: 948 QEAENKKRSQDDRARQLKGLEEKVSRLETELDEEKNTVELLTDRVNRGRDQVDQLRTELM 1007
Query: 81 EQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELA 140
++ QD + ++ ++ + + + LE Q L QE+LQ
Sbjct: 1008 QERSARQDLECDKISLERQNKDLKTRLASSEGFQKPSASLSQLESQNQLL--QERLQAEE 1065
Query: 141 PIPDLLKATQMRLK 154
+L++T +L+
Sbjct: 1066 REKTVLQSTNRKLE 1079
>AL132765-6|CAC10587.1| 977|Homo sapiens ribosome binding protein 1
homolog 180kDa (dog) protein.
Length = 977
Score = 45.2 bits (102), Expect = 4e-04
Identities = 87/410 (21%), Positives = 160/410 (39%), Gaps = 39/410 (9%)
Query: 17 RCQHRETQNKLRELEMKFEGLATHTNM----LMGSKEQAFEQEVNVRALKQCYREAREEI 72
+ HRE++ L++ + HT L E+A EQ+ + L + + E+
Sbjct: 437 QASHRESEEALQKRLDEVSRELCHTQSSHASLRADAEKAQEQQQQMAELHSKLQSSEAEV 496
Query: 73 DELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKF 132
+ + QLQ+ R + QL E R R ++ + Q +
Sbjct: 497 RSKCEELSGLHGQLQEARA---ENSQLTERIRSIEALLEAGQARDAQDVQAS-QAEADQQ 552
Query: 133 QEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNA--------EQLARELNCAREKVVHI 184
Q +L+EL L+ + L++A + Q + ++ E LA +EK++ +
Sbjct: 553 QTRLKELESQVSGLEKEAIELREAVEQQKVKNNDLREKNWKAMEALATAEQACKEKLLSL 612
Query: 185 FRYLYS----LYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNS---LKPPEKPPE 237
+ L L+ T+ S + + N + + L LK P P E
Sbjct: 613 TQAKEESEKQLCLIEAQTMEALLALLPELSVLAQQNYTEWLQDLKEKGPTLLKHPPAPAE 672
Query: 238 RGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHEC-AQ 296
D L ++ + E +L++E ++ ++ + TE +K ++E+ A+
Sbjct: 673 PSSD------LASKLREAEETQSTLQAECDQYRSILAETEGMLRDLQKSVEEEEQVWRAK 726
Query: 297 LGG---ELDRTR------DEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTA 347
+G EL ++R +E L+ E ++ VR+ AELE+ +AA+ A+
Sbjct: 727 VGAAEEELQKSRVTVKHLEEIVEKLKGELESSDQVREHTSHLEAELEKHMAAASAECQNY 786
Query: 348 EKEREELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRRTASSTGDGD 397
KE L+ L +L +AQ + L Q L S DGD
Sbjct: 787 AKEVAGLRQLLLESQSQLDAAKSEAQKQSDELALVRQQLSEMKSHVEDGD 836
Score = 43.2 bits (97), Expect = 0.002
Identities = 80/398 (20%), Positives = 150/398 (37%), Gaps = 38/398 (9%)
Query: 17 RCQHRETQNKLRELEMKFE-GLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDEL 75
R ++ + ++R +E E G A + S+ +A +Q+ ++ L+ +E EL
Sbjct: 514 RAENSQLTERIRSIEALLEAGQARDAQDVQASQAEADQQQTRLKELESQVSGLEKEAIEL 573
Query: 76 RTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEK 135
R +++Q + D R K +A + + + T+ E+ ++ ++ + E
Sbjct: 574 REAVEQQKVKNNDLREKNWKAMEALATAEQACKEKLLSLTQAKEESEKQLCLIEAQTMEA 633
Query: 136 LQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVT 195
L LA +P+L Q + Q + L + E + L
Sbjct: 634 L--LALLPELSVLAQQNYTEWLQD---LKEKGPTLLKHPPAPAEPSSDLASKLREAEETQ 688
Query: 196 TMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKP--PERGGDEKQMALLNQRIS 253
+ + D + +E +D L S++ E+ + G E+++ +
Sbjct: 689 STLQAECDQYRSILAETEGMLRD------LQKSVEEEEQVWRAKVGAAEEELQKSRVTVK 742
Query: 254 QLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTR-------- 305
L E LK E+E T EK + EC E+ R
Sbjct: 743 HLEEIVEKLKGELESSDQVREHTSHLEAELEKHMAAASAECQNYAKEVAGLRQLLLESQS 802
Query: 306 --DEASRALQRAHEQTETVRKCLQTTVAELER-QLA---ASRAQVSTAEKEREELKNRLH 359
D A Q+ ++ VR+ L + +E +A AS + AE++ +LK +L
Sbjct: 803 QLDAAKSEAQKQSDELALVRQQLSEMKSHVEDGDIAGAPASSPEAPPAEQDPVQLKTQLE 862
Query: 360 W----------QMKRLTENFEQAQLRILGLQTQVQSLR 387
W Q ++LT FE+AQ LQ +++ LR
Sbjct: 863 WTEAILEDEQTQRQKLTAEFEEAQTSACRLQEELEKLR 900
Score = 33.9 bits (74), Expect = 1.1
Identities = 39/177 (22%), Positives = 79/177 (44%), Gaps = 13/177 (7%)
Query: 242 EKQMALLNQRISQLAENNISLKSEIERLKASVIRTEE--SAL-ANEKRLQEKMHECAQLG 298
+K++ +++ + ++ SL+++ E+ + + E S L ++E ++ K E + L
Sbjct: 448 QKRLDEVSRELCHTQSSHASLRADAEKAQEQQQQMAELHSKLQSSEAEVRSKCEELSGLH 507
Query: 299 GELDRTRDEASRALQRAHE-----QTETVRKC--LQTTVAELERQ---LAASRAQVSTAE 348
G+L R E S+ +R + R +Q + AE ++Q L +QVS E
Sbjct: 508 GQLQEARAENSQLTERIRSIEALLEAGQARDAQDVQASQAEADQQQTRLKELESQVSGLE 567
Query: 349 KEREELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRRTASSTGDGDGENQECTC 405
KE EL+ + Q + + E+ + L T Q+ + S E+++ C
Sbjct: 568 KEAIELREAVEQQKVKNNDLREKNWKAMEALATAEQACKEKLLSLTQAKEESEKQLC 624
Score = 31.9 bits (69), Expect = 4.3
Identities = 38/188 (20%), Positives = 80/188 (42%), Gaps = 8/188 (4%)
Query: 201 QEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNI 260
QE L +++ R ++ ++ L ++L E ++A L Q +S++++ +
Sbjct: 351 QEQLENGPNTQLARLQQENSI---LRDALNQATSQVE-SKQNAELAKLRQELSKVSKELV 406
Query: 261 SLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTE 320
+ + + E A A EK++ + + L + DE SR L
Sbjct: 407 EKSEAVRQDEQQRKALEAKAAAFEKQVLQLQASHRESEEALQKRLDEVSRELCHTQSSHA 466
Query: 321 TVRKCLQTTVAELERQLAA--SRAQVSTAE-KEREELKNRLHWQMKRLTENFEQAQLRIL 377
++R + E ++Q+A S+ Q S AE + + E + LH Q++ Q RI
Sbjct: 467 SLRADAE-KAQEQQQQMAELHSKLQSSEAEVRSKCEELSGLHGQLQEARAENSQLTERIR 525
Query: 378 GLQTQVQS 385
++ +++
Sbjct: 526 SIEALLEA 533
>AL132765-4|CAH74034.1| 1410|Homo sapiens ribosome binding protein 1
homolog 180kDa (dog) protein.
Length = 1410
Score = 45.2 bits (102), Expect = 4e-04
Identities = 87/410 (21%), Positives = 160/410 (39%), Gaps = 39/410 (9%)
Query: 17 RCQHRETQNKLRELEMKFEGLATHTNM----LMGSKEQAFEQEVNVRALKQCYREAREEI 72
+ HRE++ L++ + HT L E+A EQ+ + L + + E+
Sbjct: 870 QASHRESEEALQKRLDEVSRELCHTQSSHASLRADAEKAQEQQQQMAELHSKLQSSEAEV 929
Query: 73 DELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKF 132
+ + QLQ+ R + QL E R R ++ + Q +
Sbjct: 930 RSKCEELSGLHGQLQEARA---ENSQLTERIRSIEALLEAGQARDAQDVQAS-QAEADQQ 985
Query: 133 QEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNA--------EQLARELNCAREKVVHI 184
Q +L+EL L+ + L++A + Q + ++ E LA +EK++ +
Sbjct: 986 QTRLKELESQVSGLEKEAIELREAVEQQKVKNNDLREKNWKAMEALATAEQACKEKLLSL 1045
Query: 185 FRYLYS----LYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNS---LKPPEKPPE 237
+ L L+ T+ S + + N + + L LK P P E
Sbjct: 1046 TQAKEESEKQLCLIEAQTMEALLALLPELSVLAQQNYTEWLQDLKEKGPTLLKHPPAPAE 1105
Query: 238 RGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHEC-AQ 296
D L ++ + E +L++E ++ ++ + TE +K ++E+ A+
Sbjct: 1106 PSSD------LASKLREAEETQSTLQAECDQYRSILAETEGMLRDLQKSVEEEEQVWRAK 1159
Query: 297 LGG---ELDRTR------DEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTA 347
+G EL ++R +E L+ E ++ VR+ AELE+ +AA+ A+
Sbjct: 1160 VGAAEEELQKSRVTVKHLEEIVEKLKGELESSDQVREHTSHLEAELEKHMAAASAECQNY 1219
Query: 348 EKEREELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRRTASSTGDGD 397
KE L+ L +L +AQ + L Q L S DGD
Sbjct: 1220 AKEVAGLRQLLLESQSQLDAAKSEAQKQSDELALVRQQLSEMKSHVEDGD 1269
Score = 43.2 bits (97), Expect = 0.002
Identities = 80/398 (20%), Positives = 150/398 (37%), Gaps = 38/398 (9%)
Query: 17 RCQHRETQNKLRELEMKFE-GLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDEL 75
R ++ + ++R +E E G A + S+ +A +Q+ ++ L+ +E EL
Sbjct: 947 RAENSQLTERIRSIEALLEAGQARDAQDVQASQAEADQQQTRLKELESQVSGLEKEAIEL 1006
Query: 76 RTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEK 135
R +++Q + D R K +A + + + T+ E+ ++ ++ + E
Sbjct: 1007 REAVEQQKVKNNDLREKNWKAMEALATAEQACKEKLLSLTQAKEESEKQLCLIEAQTMEA 1066
Query: 136 LQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVT 195
L LA +P+L Q + Q + L + E + L
Sbjct: 1067 L--LALLPELSVLAQQNYTEWLQD---LKEKGPTLLKHPPAPAEPSSDLASKLREAEETQ 1121
Query: 196 TMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKP--PERGGDEKQMALLNQRIS 253
+ + D + +E +D L S++ E+ + G E+++ +
Sbjct: 1122 STLQAECDQYRSILAETEGMLRD------LQKSVEEEEQVWRAKVGAAEEELQKSRVTVK 1175
Query: 254 QLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTR-------- 305
L E LK E+E T EK + EC E+ R
Sbjct: 1176 HLEEIVEKLKGELESSDQVREHTSHLEAELEKHMAAASAECQNYAKEVAGLRQLLLESQS 1235
Query: 306 --DEASRALQRAHEQTETVRKCLQTTVAELER-QLA---ASRAQVSTAEKEREELKNRLH 359
D A Q+ ++ VR+ L + +E +A AS + AE++ +LK +L
Sbjct: 1236 QLDAAKSEAQKQSDELALVRQQLSEMKSHVEDGDIAGAPASSPEAPPAEQDPVQLKTQLE 1295
Query: 360 W----------QMKRLTENFEQAQLRILGLQTQVQSLR 387
W Q ++LT FE+AQ LQ +++ LR
Sbjct: 1296 WTEAILEDEQTQRQKLTAEFEEAQTSACRLQEELEKLR 1333
Score = 33.9 bits (74), Expect = 1.1
Identities = 39/177 (22%), Positives = 79/177 (44%), Gaps = 13/177 (7%)
Query: 242 EKQMALLNQRISQLAENNISLKSEIERLKASVIRTEE--SAL-ANEKRLQEKMHECAQLG 298
+K++ +++ + ++ SL+++ E+ + + E S L ++E ++ K E + L
Sbjct: 881 QKRLDEVSRELCHTQSSHASLRADAEKAQEQQQQMAELHSKLQSSEAEVRSKCEELSGLH 940
Query: 299 GELDRTRDEASRALQRAHE-----QTETVRKC--LQTTVAELERQ---LAASRAQVSTAE 348
G+L R E S+ +R + R +Q + AE ++Q L +QVS E
Sbjct: 941 GQLQEARAENSQLTERIRSIEALLEAGQARDAQDVQASQAEADQQQTRLKELESQVSGLE 1000
Query: 349 KEREELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRRTASSTGDGDGENQECTC 405
KE EL+ + Q + + E+ + L T Q+ + S E+++ C
Sbjct: 1001 KEAIELREAVEQQKVKNNDLREKNWKAMEALATAEQACKEKLLSLTQAKEESEKQLC 1057
Score = 31.9 bits (69), Expect = 4.3
Identities = 38/188 (20%), Positives = 80/188 (42%), Gaps = 8/188 (4%)
Query: 201 QEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNI 260
QE L +++ R ++ ++ L ++L E ++A L Q +S++++ +
Sbjct: 784 QEQLENGPNTQLARLQQENSI---LRDALNQATSQVE-SKQNAELAKLRQELSKVSKELV 839
Query: 261 SLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTE 320
+ + + E A A EK++ + + L + DE SR L
Sbjct: 840 EKSEAVRQDEQQRKALEAKAAAFEKQVLQLQASHRESEEALQKRLDEVSRELCHTQSSHA 899
Query: 321 TVRKCLQTTVAELERQLAA--SRAQVSTAE-KEREELKNRLHWQMKRLTENFEQAQLRIL 377
++R + E ++Q+A S+ Q S AE + + E + LH Q++ Q RI
Sbjct: 900 SLRADAE-KAQEQQQQMAELHSKLQSSEAEVRSKCEELSGLHGQLQEARAENSQLTERIR 958
Query: 378 GLQTQVQS 385
++ +++
Sbjct: 959 SIEALLEA 966
>AK093227-1|BAC04102.1| 550|Homo sapiens protein ( Homo sapiens
cDNA FLJ35908 fis, clone TESTI2009935. ).
Length = 550
Score = 45.2 bits (102), Expect = 4e-04
Identities = 65/344 (18%), Positives = 143/344 (41%), Gaps = 28/344 (8%)
Query: 53 EQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXX 112
+ + + +LK+ +A + +D ++ + + + + + +LVE+
Sbjct: 87 DDQTTIASLKKEIEKAWKMVDSAYDKEQKAKETILALKEEIVNLTKLVEQG---SGLSMD 143
Query: 113 XNTRISEQINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLAR 172
++ I + + + + V + + L E+ + + L T + ++ ++++ AEH Q +
Sbjct: 144 QHSNIRDLLRFK-EEVTKERDQLLSEVVKLRESLAQTTEQQQETERSKEEAEHAISQFQQ 202
Query: 173 ELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPP 232
E+ + + FR L E Q Q+++ ++ + L K
Sbjct: 203 EIQQRQNEASREFRKKEKL----------EKELKQIQADMD--SRQTEIKALQQYVQKSK 250
Query: 233 EKPPERGGDEKQMALLNQR----ISQLAENNISLKSEIER--LKASVIRTEESALANE-K 285
E+ + K+ +LN+R + Q N L+ E E+ L + E A E K
Sbjct: 251 EELQKLEQQLKEQKILNERAAKELEQFQMRNAKLQQENEQHSLVCEQLSQENQQKALELK 310
Query: 286 RLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETV---RKCLQTTVAELERQLAASRA 342
+E++H+ G+L++ R++ + L +Q V ++ L+ + LER++ AS+
Sbjct: 311 AKEEEVHQMRLDIGKLNKIREQIHKKLHHTEDQKAEVEQHKETLKNQIVGLEREVEASKK 370
Query: 343 QVSTAEKEREELKNRLHWQMKRLTE--NFEQAQLRILGLQTQVQ 384
Q K +EL K + + N Q Q ++ L Q +
Sbjct: 371 QAELDRKAMDELLRERDILNKNMLKAVNATQKQTDLVKLHEQAK 414
Score = 38.7 bits (86), Expect = 0.037
Identities = 68/380 (17%), Positives = 161/380 (42%), Gaps = 28/380 (7%)
Query: 21 RETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDE------ 74
+E + K L +K E + T ++ + +Q N+R L + E +E D+
Sbjct: 112 KEQKAKETILALK-EEIVNLTKLVEQGSGLSMDQHSNIRDLLRFKEEVTKERDQLLSEVV 170
Query: 75 -LRTLMKEQNDQLQDYRVKYLQAQQLV---EEQRRQXXXXXXXNTRISEQINLEIQRVKL 130
LR + + +Q Q+ +A+ + +++ +Q R E++ E+++++
Sbjct: 171 KLRESLAQTTEQQQETERSKEEAEHAISQFQQEIQQRQNEASREFRKKEKLEKELKQIQA 230
Query: 131 KFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYS 190
+ E+ + ++ ++ L+ +Q + E+ A+EL + + + +
Sbjct: 231 DMDSRQTEIKALQQYVQKSKEELQKLEQQLKEQKILNERAAKELEQFQMRNAKLQQENEQ 290
Query: 191 LYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQ 250
LV L+QE+ Q + K++ VH + L + R K++
Sbjct: 291 HSLVCEQ-LSQEN----QQKALELKAKEEEVHQM---RLDIGKLNKIREQIHKKLHHTED 342
Query: 251 RISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASR 310
+ +++ ++ +LK++I L+ V +++ A + K + E + E L + + + +
Sbjct: 343 QKAEVEQHKETLKNQIVGLEREVEASKKQAELDRKAMDELLRERDILNKNMLKAVNATQK 402
Query: 311 A--LQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTEN 368
L + HEQ ++ L+ + + + R + EKER+ N+ +++ N
Sbjct: 403 QTDLVKLHEQ---AKRNLEGEIQNYKDEAQKQRKIIFHLEKERDRYINQASDLTQKVLMN 459
Query: 369 FEQAQLRILGLQTQVQSLRR 388
E ++R +TQ+ R+
Sbjct: 460 MEDIKVR----ETQIFDYRK 475
>AK022912-1|BAB14305.1| 472|Homo sapiens protein ( Homo sapiens
cDNA FLJ12850 fis, clone NT2RP2003394, weakly similar to
INTRACELLULAR PROTEIN TRANSPORT PROTEIN USO1. ).
Length = 472
Score = 45.2 bits (102), Expect = 4e-04
Identities = 58/271 (21%), Positives = 117/271 (43%), Gaps = 7/271 (2%)
Query: 94 LQAQQLVEE-QRRQXXXXXXXNTRISEQINL-EIQRVKLKFQE-KLQELAPIPDLLKATQ 150
L ++L+E+ Q + RIS+ +++ E++ L +E +LQ+L L A
Sbjct: 162 LNIEELIEKLQSGMVVKDQICDVRISDIMDVYEMKLSTLASKESRLQDLLETKALALAQA 221
Query: 151 MRLKDAQQAQAI-AEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQ 209
RL + Q AE A LA L K + L + + + + + Q
Sbjct: 222 DRLIAQHRCQRTQAETEARTLASMLREVERKNEELSVLLKAQQVESERAQSDIEHLFQHN 281
Query: 210 SEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMAL--LNQRISQLAENNISLKSEIE 267
++ ++ + + L + E+ + Q+ LN++I + + N SLK + E
Sbjct: 282 RKLESVAEEHEILTKSYMELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNESLKEQNE 341
Query: 268 RLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQ 327
+ A +I EE + +L ++ H+ A L + + ++E + LQ+ E E L+
Sbjct: 342 KSIAQLIEKEEQRKEVQNQLVDREHKLANL-HQKTKVQEEKIKTLQKEREDKEETIDILR 400
Query: 328 TTVAELERQLAASRAQVSTAEKEREELKNRL 358
++ E+ + S+ E ++ +L+ RL
Sbjct: 401 KELSRTEQIRKELSIKASSLEVQKAQLEGRL 431
>AF334474-1|AAL11632.1| 905|Homo sapiens p90 autoantigen protein.
Length = 905
Score = 45.2 bits (102), Expect = 4e-04
Identities = 58/271 (21%), Positives = 117/271 (43%), Gaps = 7/271 (2%)
Query: 94 LQAQQLVEE-QRRQXXXXXXXNTRISEQINL-EIQRVKLKFQE-KLQELAPIPDLLKATQ 150
L ++L+E+ Q + RIS+ +++ E++ L +E +LQ+L L A
Sbjct: 595 LNIEELIEKLQSGMVVKDQICDVRISDIMDVYEMKLSTLASKESRLQDLLETKALALAQA 654
Query: 151 MRLKDAQQAQAI-AEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQ 209
RL + Q AE A LA L K + L + + + + + Q
Sbjct: 655 DRLIAQHRCQRTQAETEARTLASMLREVERKNEELSVLLKAQQVESERAQSDIEHLFQHN 714
Query: 210 SEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMAL--LNQRISQLAENNISLKSEIE 267
++ ++ + + L + E+ + Q+ LN++I + + N SLK + E
Sbjct: 715 RKLESVAEEHEILTKSYMELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNESLKEQNE 774
Query: 268 RLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQ 327
+ A +I EE + +L ++ H+ A L + + ++E + LQ+ E E L+
Sbjct: 775 KSIAQLIEKEEQRKEVQNQLVDREHKLANL-HQKTKVQEEKIKTLQKEREDKEETIDILR 833
Query: 328 TTVAELERQLAASRAQVSTAEKEREELKNRL 358
++ E+ + S+ E ++ +L+ RL
Sbjct: 834 KELSRTEQIRKELSIKASSLEVQKAQLEGRL 864
>AF263462-1|AAF74498.1| 1203|Homo sapiens cingulin protein.
Length = 1203
Score = 45.2 bits (102), Expect = 4e-04
Identities = 78/361 (21%), Positives = 156/361 (43%), Gaps = 25/361 (6%)
Query: 21 RETQNKLRELEMKFEG----LATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELR 76
R T+ +L +L M+ E L +L EQA + R ++ +E +EL+
Sbjct: 583 RATKQELLQLRMEKEEMEEELGEKIEVLQRELEQARASAGDTRQVEVLKKELLRTQEELK 642
Query: 77 TLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKL 136
L E+ Q V + +E+Q + EQ NL++Q+ + ++
Sbjct: 643 ELQAERQSQ----EVAGRHRDRELEKQLAVLRVEADRGRELEEQ-NLQLQKTLQQLRQDC 697
Query: 137 QELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLY-LVT 195
+E + + +A L Q +A E + E + R +++ + + L LV
Sbjct: 698 EEASKAKMVAEAEATVL---GQRRAAVETTLRETQEENDEFRRRILGLEQQLKETRGLVD 754
Query: 196 TMTLTQEDLFGQSQS-EIGRGNKDQTVHVLL--HNSLKPPEKPPERGGDEKQMALLNQRI 252
+ L + Q E + ++ ++ SL ++ E +E Q L R+
Sbjct: 755 GGEAVEARLRDKLQRLEAEKQQLEEALNASQEEEGSLAAAKRALEARLEEAQRGL--ARL 812
Query: 253 SQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRAL 312
Q + ++ E E + V+R ++ L +KRL ++ + +L EL++ +++ +AL
Sbjct: 813 GQ-EQQTLNRALEEEGKQREVLRRGKAELEEQKRLLDRTVD--RLNKELEKIGEDSKQAL 869
Query: 313 QRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQA 372
Q+ Q E ++ + VA+ +RQ ++ S AEK L +RL +++RL + + +
Sbjct: 870 QQLQAQLEDYKEKARREVADAQRQ---AKDWASEAEKTSGGL-SRLQDEIQRLRQALQAS 925
Query: 373 Q 373
Q
Sbjct: 926 Q 926
Score = 43.6 bits (98), Expect = 0.001
Identities = 71/368 (19%), Positives = 157/368 (42%), Gaps = 25/368 (6%)
Query: 24 QNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQN 83
++KL+ LE + + L N S+E+ RAL+ EA+ + L + N
Sbjct: 764 RDKLQRLEAEKQQLEEALN---ASQEEEGSLAAAKRALEARLEEAQRGLARLGQEQQTLN 820
Query: 84 DQLQD---YRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQEL- 139
L++ R + + +EEQ+R R +++N E++++ ++ LQ+L
Sbjct: 821 RALEEEGKQREVLRRGKAELEEQKRLLD-------RTVDRLNKELEKIGEDSKQALQQLQ 873
Query: 140 APIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTL 199
A + D + + + DAQ+ AE+ + L+ ++++ + + L +
Sbjct: 874 AQLEDYKEKARREVADAQRQAKDWASEAEKTSGGLSRLQDEIQRLRQALQASQAERDTAR 933
Query: 200 TQEDLFGQ------SQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRIS 253
++L Q ++E + ++D L K E ++ + LL R++
Sbjct: 934 LDKELLAQRLQGLEQEAENKKRSQDDRARQLKGLEEKVSRLETELDEEKNTVELLTDRVN 993
Query: 254 QLAENNISLKSEI--ERLKASVIRTEESALANE-KRLQEKM--HECAQLGGELDRTRDEA 308
+ + L++E+ ER + ++ +L + K L+ ++ E Q +
Sbjct: 994 RGRDQVDQLRTELMQERSARQDLECDKISLERQNKDLKTRLASSEGFQKPSASLSQLESQ 1053
Query: 309 SRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTEN 368
++ LQ + E + LQ+T +LER++ Q+ + + K++L ++K L
Sbjct: 1054 NQLLQERLQAEEREKTVLQSTNRKLERKVKELSIQIEDERQHVNDQKDQLSLRVKALKRQ 1113
Query: 369 FEQAQLRI 376
++A+ I
Sbjct: 1114 VDEAEEEI 1121
Score = 43.2 bits (97), Expect = 0.002
Identities = 71/340 (20%), Positives = 136/340 (40%), Gaps = 20/340 (5%)
Query: 60 ALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISE 119
ALK+ +E++ +R + +QL+ Q ++E +R++ R E
Sbjct: 503 ALKEEVASRDQEVEHVRQQYQRDTEQLRRSMQDATQDHAVLEAERQKMSALVRGLQRELE 562
Query: 120 QINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCARE 179
+ + E + FQ+ ++L L Q+R++ + + + E E L REL AR
Sbjct: 563 ETSEETGHWQSMFQKNKEDLRATKQEL--LQLRMEKEEMEEELGE-KIEVLQRELEQARA 619
Query: 180 KV--VHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPE 237
L L T L + QSQ GR ++D+ L L +
Sbjct: 620 SAGDTRQVEVLKKELLRTQEELKELQAERQSQEVAGR-HRDRE----LEKQLAVLRVEAD 674
Query: 238 RGGD-EKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKR--LQEKMHEC 294
RG + E+Q L + + QL ++ E E KA ++ E+ + ++R ++ + E
Sbjct: 675 RGRELEEQNLQLQKTLQQLRQD-----CE-EASKAKMVAEAEATVLGQRRAAVETTLRET 728
Query: 295 AQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREEL 354
+ E R + L+ + + ++ + + ++L A + Q+ A +E
Sbjct: 729 QEENDEFRRRILGLEQQLKETRGLVDG-GEAVEARLRDKLQRLEAEKQQLEEALNASQEE 787
Query: 355 KNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRRTASSTG 394
+ L + L E+AQ + L + Q+L R G
Sbjct: 788 EGSLAAAKRALEARLEEAQRGLARLGQEQQTLNRALEEEG 827
Score = 41.5 bits (93), Expect = 0.005
Identities = 92/377 (24%), Positives = 148/377 (39%), Gaps = 36/377 (9%)
Query: 28 RELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQ 87
RELE E +M +KE ++RA KQ E+ +LR +E ++L
Sbjct: 559 RELEETSEETGHWQSMFQKNKE-------DLRATKQ-------ELLQLRMEKEEMEEELG 604
Query: 88 DYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELA---PIPD 144
+ +++ LQ + +E+ R E + + + +L+ + + QE+A +
Sbjct: 605 E-KIEVLQRE--LEQARASAGDTRQVEVLKKELLRTQEELKELQAERQSQEVAGRHRDRE 661
Query: 145 LLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDL 204
L K + +A + + + E N QL + L R+ + T+ +
Sbjct: 662 LEKQLAVLRVEADRGRELEEQNL-QLQKTLQQLRQDCEEASKAKMVAEAEATVLGQRRAA 720
Query: 205 FGQSQSEIGRGNKDQTVHVL-LHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLK 263
+ E N + +L L LK E G E A L ++ +L L+
Sbjct: 721 VETTLRETQEENDEFRRRILGLEQQLK--ETRGLVDGGEAVEARLRDKLQRLEAEKQQLE 778
Query: 264 SEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVR 323
E L AS + EE +LA KR E E AQ G L R E + L RA E+ R
Sbjct: 779 ---EALNAS--QEEEGSLAAAKRALEARLEEAQRG--LARLGQE-QQTLNRALEEEGKQR 830
Query: 324 KCLQTTVAELERQLAASRAQVSTAEKEREEL----KNRLHWQMKRLTENFEQAQLRILGL 379
+ L+ AELE Q V KE E++ K L +L + E+A+ +
Sbjct: 831 EVLRRGKAELEEQKRLLDRTVDRLNKELEKIGEDSKQALQQLQAQLEDYKEKARREVADA 890
Query: 380 QTQVQSLRRTASSTGDG 396
Q Q + A T G
Sbjct: 891 QRQAKDWASEAEKTSGG 907
Score = 39.9 bits (89), Expect = 0.016
Identities = 29/104 (27%), Positives = 55/104 (52%), Gaps = 10/104 (9%)
Query: 240 GDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGG 299
G K +A + ++ E L E+++ + + E S + E++L+EK EC++L
Sbjct: 353 GSTKAVAGQGELTRKVEELQRKLDEEVKKRQ----KLEPSQVGLERQLEEKTEECSRLQE 408
Query: 300 ELDRTRDEASRA------LQRAHEQTETVRKCLQTTVAELERQL 337
L+R + EA ++ ++R +Q E +R L+T V EL+ +L
Sbjct: 409 LLERRKGEAQQSNKELQNMKRLLDQGEDLRHGLETQVMELQNKL 452
Score = 39.5 bits (88), Expect = 0.021
Identities = 41/170 (24%), Positives = 74/170 (43%), Gaps = 5/170 (2%)
Query: 223 VLLHNSLKPPEKPPE-RGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESAL 281
VLL + L+ E E G ++ L R +L +LK E+ V +
Sbjct: 464 VLLKDLLETRELLEEVLEGKQRVEEQLRLRERELTALKGALKEEVASRDQEVEHVRQQYQ 523
Query: 282 ANEKRLQEKMHECAQLGGELDRTRDEAS---RALQRAHEQTETVRKCLQTTVAELERQLA 338
+ ++L+ M + Q L+ R + S R LQR E+T Q+ + + L
Sbjct: 524 RDTEQLRRSMQDATQDHAVLEAERQKMSALVRGLQRELEETSEETGHWQSMFQKNKEDLR 583
Query: 339 ASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRR 388
A++ ++ E+EE++ L +++ L EQA+ G QV+ L++
Sbjct: 584 ATKQELLQLRMEKEEMEEELGEKIEVLQRELEQARAS-AGDTRQVEVLKK 632
Score = 34.3 bits (75), Expect = 0.80
Identities = 20/69 (28%), Positives = 38/69 (55%), Gaps = 6/69 (8%)
Query: 20 HRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLM 79
+R+ + K++EL ++ E H N +Q + + V+ALK+ EA EEI+ L L
Sbjct: 1075 NRKLERKVKELSIQIEDERQHVN------DQKDQLSLRVKALKRQVDEAEEEIERLDGLR 1128
Query: 80 KEQNDQLQD 88
K+ ++++
Sbjct: 1129 KKAQREVEE 1137
Score = 31.9 bits (69), Expect = 4.3
Identities = 26/134 (19%), Positives = 56/134 (41%), Gaps = 2/134 (1%)
Query: 21 RETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMK 80
+E +NK R + + L + + + E++ V L R+++D+LRT +
Sbjct: 948 QEAENKKRSQDDRARQLKGLEEKVSRLETELDEEKNTVELLTDRVNRGRDQVDQLRTELM 1007
Query: 81 EQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELA 140
++ QD + ++ ++ + + + LE Q L QE+LQ
Sbjct: 1008 QERSARQDLECDKISLERQNKDLKTRLASSEGFQKPSASLSQLESQNQLL--QERLQAEE 1065
Query: 141 PIPDLLKATQMRLK 154
+L++T +L+
Sbjct: 1066 REKTVLQSTNRKLE 1079
>AB040957-1|BAA96048.1| 884|Homo sapiens KIAA1524 protein protein.
Length = 884
Score = 45.2 bits (102), Expect = 4e-04
Identities = 58/271 (21%), Positives = 117/271 (43%), Gaps = 7/271 (2%)
Query: 94 LQAQQLVEE-QRRQXXXXXXXNTRISEQINL-EIQRVKLKFQE-KLQELAPIPDLLKATQ 150
L ++L+E+ Q + RIS+ +++ E++ L +E +LQ+L L A
Sbjct: 574 LNIEELIEKLQSGMVVKDQICDVRISDIMDVYEMKLSTLASKESRLQDLLETKALALAQA 633
Query: 151 MRLKDAQQAQAI-AEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQ 209
RL + Q AE A LA L K + L + + + + + Q
Sbjct: 634 DRLIAQHRCQRTQAETEARTLASMLREVERKNEELSVLLKAQQVESERAQSDIEHLFQHN 693
Query: 210 SEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMAL--LNQRISQLAENNISLKSEIE 267
++ ++ + + L + E+ + Q+ LN++I + + N SLK + E
Sbjct: 694 RKLESVAEEHEILTKSYMELLQRNESTEKKNKDLQITCDSLNKQIETVKKLNESLKEQNE 753
Query: 268 RLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQ 327
+ A +I EE + +L ++ H+ A L + + ++E + LQ+ E E L+
Sbjct: 754 KSIAQLIEKEEQRKEVQNQLVDREHKLANL-HQKTKVQEEKIKTLQKEREDKEETIDILR 812
Query: 328 TTVAELERQLAASRAQVSTAEKEREELKNRL 358
++ E+ + S+ E ++ +L+ RL
Sbjct: 813 KELSRTEQIRKELSIKASSLEVQKAQLEGRL 843
>AB037740-1|BAA92557.1| 1208|Homo sapiens KIAA1319 protein protein.
Length = 1208
Score = 45.2 bits (102), Expect = 4e-04
Identities = 78/361 (21%), Positives = 156/361 (43%), Gaps = 25/361 (6%)
Query: 21 RETQNKLRELEMKFEG----LATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELR 76
R T+ +L +L M+ E L +L EQA + R ++ +E +EL+
Sbjct: 588 RATKQELLQLRMEKEEMEEELGEKIEVLQRELEQARASAGDTRQVEVLKKELLRTQEELK 647
Query: 77 TLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKL 136
L E+ Q V + +E+Q + EQ NL++Q+ + ++
Sbjct: 648 ELQAERQSQ----EVAGRHRDRELEKQLAVLRVEADRGRELEEQ-NLQLQKTLQQLRQDC 702
Query: 137 QELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLY-LVT 195
+E + + +A L Q +A E + E + R +++ + + L LV
Sbjct: 703 EEASKAKMVAEAEATVL---GQRRAAVETTLRETQEENDEFRRRILGLEQQLKETRGLVD 759
Query: 196 TMTLTQEDLFGQSQS-EIGRGNKDQTVHVLL--HNSLKPPEKPPERGGDEKQMALLNQRI 252
+ L + Q E + ++ ++ SL ++ E +E Q L R+
Sbjct: 760 GGEAVEARLRDKLQRLEAEKQQLEEALNASQEEEGSLAAAKRALEARLEEAQRGL--ARL 817
Query: 253 SQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRAL 312
Q + ++ E E + V+R ++ L +KRL ++ + +L EL++ +++ +AL
Sbjct: 818 GQ-EQQTLNRALEEEGKQREVLRRGKAELEEQKRLLDRTVD--RLNKELEKIGEDSKQAL 874
Query: 313 QRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQA 372
Q+ Q E ++ + VA+ +RQ ++ S AEK L +RL +++RL + + +
Sbjct: 875 QQLQAQLEDYKEKARREVADAQRQ---AKDWASEAEKTSGGL-SRLQDEIQRLRQALQAS 930
Query: 373 Q 373
Q
Sbjct: 931 Q 931
Score = 43.6 bits (98), Expect = 0.001
Identities = 71/368 (19%), Positives = 157/368 (42%), Gaps = 25/368 (6%)
Query: 24 QNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQN 83
++KL+ LE + + L N S+E+ RAL+ EA+ + L + N
Sbjct: 769 RDKLQRLEAEKQQLEEALN---ASQEEEGSLAAAKRALEARLEEAQRGLARLGQEQQTLN 825
Query: 84 DQLQD---YRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQEL- 139
L++ R + + +EEQ+R R +++N E++++ ++ LQ+L
Sbjct: 826 RALEEEGKQREVLRRGKAELEEQKRLLD-------RTVDRLNKELEKIGEDSKQALQQLQ 878
Query: 140 APIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTL 199
A + D + + + DAQ+ AE+ + L+ ++++ + + L +
Sbjct: 879 AQLEDYKEKARREVADAQRQAKDWASEAEKTSGGLSRLQDEIQRLRQALQASQAERDTAR 938
Query: 200 TQEDLFGQ------SQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRIS 253
++L Q ++E + ++D L K E ++ + LL R++
Sbjct: 939 LDKELLAQRLQGLEQEAENKKRSQDDRARQLKGLEEKVSRLETELDEEKNTVELLTDRVN 998
Query: 254 QLAENNISLKSEI--ERLKASVIRTEESALANE-KRLQEKM--HECAQLGGELDRTRDEA 308
+ + L++E+ ER + ++ +L + K L+ ++ E Q +
Sbjct: 999 RGRDQVDQLRTELMQERSARQDLECDKISLERQNKDLKTRLASSEGFQKPSASLSQLESQ 1058
Query: 309 SRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTEN 368
++ LQ + E + LQ+T +LER++ Q+ + + K++L ++K L
Sbjct: 1059 NQLLQERLQAEEREKTVLQSTNRKLERKVKELSIQIEDERQHVNDQKDQLSLRVKALKRQ 1118
Query: 369 FEQAQLRI 376
++A+ I
Sbjct: 1119 VDEAEEEI 1126
Score = 43.2 bits (97), Expect = 0.002
Identities = 71/340 (20%), Positives = 136/340 (40%), Gaps = 20/340 (5%)
Query: 60 ALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISE 119
ALK+ +E++ +R + +QL+ Q ++E +R++ R E
Sbjct: 508 ALKEEVASRDQEVEHVRQQYQRDTEQLRRSMQDATQDHAVLEAERQKMSALVRGLQRELE 567
Query: 120 QINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCARE 179
+ + E + FQ+ ++L L Q+R++ + + + E E L REL AR
Sbjct: 568 ETSEETGHWQSMFQKNKEDLRATKQEL--LQLRMEKEEMEEELGE-KIEVLQRELEQARA 624
Query: 180 KV--VHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPE 237
L L T L + QSQ GR ++D+ L L +
Sbjct: 625 SAGDTRQVEVLKKELLRTQEELKELQAERQSQEVAGR-HRDRE----LEKQLAVLRVEAD 679
Query: 238 RGGD-EKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKR--LQEKMHEC 294
RG + E+Q L + + QL ++ E E KA ++ E+ + ++R ++ + E
Sbjct: 680 RGRELEEQNLQLQKTLQQLRQD-----CE-EASKAKMVAEAEATVLGQRRAAVETTLRET 733
Query: 295 AQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREEL 354
+ E R + L+ + + ++ + + ++L A + Q+ A +E
Sbjct: 734 QEENDEFRRRILGLEQQLKETRGLVDG-GEAVEARLRDKLQRLEAEKQQLEEALNASQEE 792
Query: 355 KNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRRTASSTG 394
+ L + L E+AQ + L + Q+L R G
Sbjct: 793 EGSLAAAKRALEARLEEAQRGLARLGQEQQTLNRALEEEG 832
Score = 41.5 bits (93), Expect = 0.005
Identities = 92/377 (24%), Positives = 148/377 (39%), Gaps = 36/377 (9%)
Query: 28 RELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQ 87
RELE E +M +KE ++RA KQ E+ +LR +E ++L
Sbjct: 564 RELEETSEETGHWQSMFQKNKE-------DLRATKQ-------ELLQLRMEKEEMEEELG 609
Query: 88 DYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELA---PIPD 144
+ +++ LQ + +E+ R E + + + +L+ + + QE+A +
Sbjct: 610 E-KIEVLQRE--LEQARASAGDTRQVEVLKKELLRTQEELKELQAERQSQEVAGRHRDRE 666
Query: 145 LLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDL 204
L K + +A + + + E N QL + L R+ + T+ +
Sbjct: 667 LEKQLAVLRVEADRGRELEEQNL-QLQKTLQQLRQDCEEASKAKMVAEAEATVLGQRRAA 725
Query: 205 FGQSQSEIGRGNKDQTVHVL-LHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLK 263
+ E N + +L L LK E G E A L ++ +L L+
Sbjct: 726 VETTLRETQEENDEFRRRILGLEQQLK--ETRGLVDGGEAVEARLRDKLQRLEAEKQQLE 783
Query: 264 SEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVR 323
E L AS + EE +LA KR E E AQ G L R E + L RA E+ R
Sbjct: 784 ---EALNAS--QEEEGSLAAAKRALEARLEEAQRG--LARLGQE-QQTLNRALEEEGKQR 835
Query: 324 KCLQTTVAELERQLAASRAQVSTAEKEREEL----KNRLHWQMKRLTENFEQAQLRILGL 379
+ L+ AELE Q V KE E++ K L +L + E+A+ +
Sbjct: 836 EVLRRGKAELEEQKRLLDRTVDRLNKELEKIGEDSKQALQQLQAQLEDYKEKARREVADA 895
Query: 380 QTQVQSLRRTASSTGDG 396
Q Q + A T G
Sbjct: 896 QRQAKDWASEAEKTSGG 912
Score = 39.9 bits (89), Expect = 0.016
Identities = 29/104 (27%), Positives = 55/104 (52%), Gaps = 10/104 (9%)
Query: 240 GDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGG 299
G K +A + ++ E L E+++ + + E S + E++L+EK EC++L
Sbjct: 358 GSTKAVAGQGELTRKVEELQRKLDEEVKKRQ----KLEPSQVGLERQLEEKTEECSRLQE 413
Query: 300 ELDRTRDEASRA------LQRAHEQTETVRKCLQTTVAELERQL 337
L+R + EA ++ ++R +Q E +R L+T V EL+ +L
Sbjct: 414 LLERRKGEAQQSNKELQNMKRLLDQGEDLRHGLETQVMELQNKL 457
Score = 39.5 bits (88), Expect = 0.021
Identities = 41/170 (24%), Positives = 74/170 (43%), Gaps = 5/170 (2%)
Query: 223 VLLHNSLKPPEKPPE-RGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESAL 281
VLL + L+ E E G ++ L R +L +LK E+ V +
Sbjct: 469 VLLKDLLETRELLEEVLEGKQRVEEQLRLRERELTALKGALKEEVASRDQEVEHVRQQYQ 528
Query: 282 ANEKRLQEKMHECAQLGGELDRTRDEAS---RALQRAHEQTETVRKCLQTTVAELERQLA 338
+ ++L+ M + Q L+ R + S R LQR E+T Q+ + + L
Sbjct: 529 RDTEQLRRSMQDATQDHAVLEAERQKMSALVRGLQRELEETSEETGHWQSMFQKNKEDLR 588
Query: 339 ASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRR 388
A++ ++ E+EE++ L +++ L EQA+ G QV+ L++
Sbjct: 589 ATKQELLQLRMEKEEMEEELGEKIEVLQRELEQARAS-AGDTRQVEVLKK 637
Score = 34.3 bits (75), Expect = 0.80
Identities = 20/69 (28%), Positives = 38/69 (55%), Gaps = 6/69 (8%)
Query: 20 HRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLM 79
+R+ + K++EL ++ E H N +Q + + V+ALK+ EA EEI+ L L
Sbjct: 1080 NRKLERKVKELSIQIEDERQHVN------DQKDQLSLRVKALKRQVDEAEEEIERLDGLR 1133
Query: 80 KEQNDQLQD 88
K+ ++++
Sbjct: 1134 KKAQREVEE 1142
Score = 31.9 bits (69), Expect = 4.3
Identities = 26/134 (19%), Positives = 56/134 (41%), Gaps = 2/134 (1%)
Query: 21 RETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMK 80
+E +NK R + + L + + + E++ V L R+++D+LRT +
Sbjct: 953 QEAENKKRSQDDRARQLKGLEEKVSRLETELDEEKNTVELLTDRVNRGRDQVDQLRTELM 1012
Query: 81 EQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELA 140
++ QD + ++ ++ + + + LE Q L QE+LQ
Sbjct: 1013 QERSARQDLECDKISLERQNKDLKTRLASSEGFQKPSASLSQLESQNQLL--QERLQAEE 1070
Query: 141 PIPDLLKATQMRLK 154
+L++T +L+
Sbjct: 1071 REKTVLQSTNRKLE 1084
>AB033102-1|BAA86590.1| 1068|Homo sapiens KIAA1276 protein protein.
Length = 1068
Score = 45.2 bits (102), Expect = 4e-04
Identities = 76/361 (21%), Positives = 143/361 (39%), Gaps = 29/361 (8%)
Query: 21 RETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQ-----EVNVRALKQCYREAREEID-E 74
+E +K++ LE ++ + +QA EQ +++ALKQ RE++ E
Sbjct: 593 KEKTSKIQRLEEDWQSQKAKLQAQVSQMQQALEQCTSNYREDLQALKQLSDLEREKLQHE 652
Query: 75 LRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQE 134
L+ ++ + + +A +++E+ R Q + +L+IQ Q
Sbjct: 653 LQETTQQNHAMKAQLEASHQRALRMLEKARHQELKATEERLKKESSHSLQIQH-----QT 707
Query: 135 KLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLV 194
EL + + KA Q ++ ++ QA E L +EL+ + + L +L
Sbjct: 708 HRLELQALEE--KARQELQEERERMQAQQALLLESLRQELSEQQAACSGHQKDLEALQAE 765
Query: 195 TTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQ 254
Q Q+ S+ +KD + PP G
Sbjct: 766 LRALGRQ-----QASSQCPGDSKDHIIATEEWGGPGQAGSPPGAAGQGSGEGC------G 814
Query: 255 LAENNISLKSEIERLKASVIRTEESA--LANEKRLQEKMHECAQLGGELDRTRDEASRAL 312
L E N L+ + RL+A V + ++ A L +++R E+ + AQ E++ R E + +
Sbjct: 815 LWEENAQLQDAVRRLRAEVEQHQQEAQKLRDQRRFLEETQQ-AQRAREVETLRQEHRKEM 873
Query: 313 QRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELK--NRLHWQMKRLTENFE 370
Q + + LQ +A LE +L S + E+L+ RL ++K + +
Sbjct: 874 QAMVADFSSAQAQLQARLAALEAELKDSGEKPGKGASRPEDLQLIGRLQTRLKEREDIIK 933
Query: 371 Q 371
Q
Sbjct: 934 Q 934
Score = 31.5 bits (68), Expect = 5.6
Identities = 52/259 (20%), Positives = 99/259 (38%), Gaps = 6/259 (2%)
Query: 24 QNKLRELEMKFEGLATHTNMLMGS-KEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQ 82
++ L+ K EG H + K+ A + + ++ L +EAR+E EL+ K+
Sbjct: 270 ESALQAQVRKLEGDLEHRGRKISDLKKYAQKLKERIQHLDVQLKEARQENSELKGTAKKL 329
Query: 83 NDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPI 142
++L + + + + +Q ++ + N +++ L Q+ L
Sbjct: 330 GEKLAVAKDRMMLQECRGTQQTDAMKTELVSENKVLREEN-DLEAGNLHPQQDQSCLKEC 388
Query: 143 PDLLKATQMRLKDAQQAQA--IAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLT 200
P + T M+ K A+ + + E L + + E+ H+ L T
Sbjct: 389 PCMKGGTDMQTKKEASAETEYMKQQYEEDLRKIKHQTEEEKKHLKDQLVKRLEDLVKKHT 448
Query: 201 QEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNI 260
E +S E R + V L K EK ++ +EK A LN ++ +
Sbjct: 449 VEIKSVRSSVEAERKKLQREVEAQLEEVRKKSEKEIKQLEEEK--AALNVKLQNSLLEVL 506
Query: 261 SLKSEIERLKASVIRTEES 279
L+ I++ K EES
Sbjct: 507 RLEEFIQQNKTRPTGAEES 525
>AB023217-1|BAA76844.2| 1956|Homo sapiens KIAA1000 protein protein.
Length = 1956
Score = 45.2 bits (102), Expect = 4e-04
Identities = 82/381 (21%), Positives = 159/381 (41%), Gaps = 43/381 (11%)
Query: 21 RETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMK 80
RE N R++E L T + + + L++ Y E +E EL +
Sbjct: 1325 REKSNFTRQIEDLRGQLEKETKSQSALAHALQKAQRDCDLLREQYEEEQEVKAELHRTLS 1384
Query: 81 EQNDQLQDYRVKY----LQAQQLVEEQRRQXXXXXXXNTR---ISEQINLEIQRVKLKFQ 133
+ N ++ +R+KY +Q + +E+ +++ ++ N ++R + + Q
Sbjct: 1385 KVNAEMVQWRMKYENNVIQRTEDLEDAKKELAIRLQEAAEAMGVANARNASLERARHQLQ 1444
Query: 134 EKLQELAPIPDLLKATQMRL--KDAQQAQAIAE-HNAEQLARELNCAREKVVHIFRYLYS 190
+L + +++ RL K Q +A+A+ + ++ L A +K V S
Sbjct: 1445 LELGDALSDLGKVRSAAARLDQKQLQSGKALADWKQKHEESQALLDASQKEVQAL----S 1500
Query: 191 LYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVL-LHNSLKPPEKPPERGGDEKQMALLN 249
L+ +E + G Q + R NK+ + L N ++ K + +M
Sbjct: 1501 TELLKLKNTYEESIVG--QETLRRENKNLQEEISNLTNQVREGTK------NLTEM---- 1548
Query: 250 QRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEAS 309
+++ +L E K+E++ + EE+ A E+ + +H QL EL + E
Sbjct: 1549 EKVKKLIEEE---KTEVQ------VTLEETEGALERNESKILH--FQL--ELLEAKAELE 1595
Query: 310 RALQRAHEQTETVRKCLQTTVAELERQL---AASRAQVSTAEKEREELKNRLHWQMKRLT 366
R L E+ E R+ Q T+ L+ L A SR +V+ +K+ EE N + Q+
Sbjct: 1596 RKLSEKDEEIENFRRKQQCTIDSLQSSLDSEAKSRIEVTRLKKKMEEDLNEMELQLSCAN 1655
Query: 367 ENFEQAQLRILGLQTQVQSLR 387
+A + LQ Q++ L+
Sbjct: 1656 RQVSEATKSLGQLQIQIKDLQ 1676
Score = 42.7 bits (96), Expect = 0.002
Identities = 75/398 (18%), Positives = 160/398 (40%), Gaps = 44/398 (11%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTL 78
+H E+Q L + + + L+T L + E++ V L++ + +EEI L
Sbjct: 1481 KHEESQALLDASQKEVQALSTELLKLKNTYEESI---VGQETLRRENKNLQEEISNLTNQ 1537
Query: 79 MKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQE 138
++E L + + ++L+EE++ + E+ +I +L E L+
Sbjct: 1538 VREGTKNLTEME----KVKKLIEEEKTEVQVTLEETEGALERNESKILHFQL---ELLEA 1590
Query: 139 LAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMT 198
A + L +++ ++ Q + + L L+ + + + R +
Sbjct: 1591 KAELERKLSEKDEEIENFRRKQ---QCTIDSLQSSLDSEAKSRIEVTRLKKKM------- 1640
Query: 199 LTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQM--ALLNQRISQLA 256
+EDL + + ++ N+ + L+ K + D+ + L ++++
Sbjct: 1641 --EEDL-NEMELQLSCANRQVSEATKSLGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAE 1697
Query: 257 ENNISLKSEIERLKASVIRTEESALANEKRLQEK--------------MHECAQLGGELD 302
N L+SE+E L++ +TE +E+ L E + + +L ++
Sbjct: 1698 RRNSLLQSELEDLRSLQEQTERGRRLSEEELLEATERINLFYTQNTSLLSQKKKLEADVA 1757
Query: 303 RTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQM 362
R + EA +Q E +K A L +L + ++ E+ RE ++ +
Sbjct: 1758 RMQKEAEEVVQECQNAEEKAKKA-AIEAANLSEELKKKQDTIAHLERTRENMEQTITDLQ 1816
Query: 363 KRLTENFEQAQLRILGLQTQVQSLR-RTASSTGDGDGE 399
KRL E Q+ ++G + Q+Q L R G+ +GE
Sbjct: 1817 KRLA---EAEQMALMGSRKQIQKLESRVRELEGELEGE 1851
Score = 40.3 bits (90), Expect = 0.012
Identities = 68/277 (24%), Positives = 125/277 (45%), Gaps = 37/277 (13%)
Query: 119 EQINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAR 178
E+IN E+ K +++ EL D L+ ++ +++ + EH + L E+
Sbjct: 952 EEINSELTARGRKLEDECFELKKEIDDLETMLVK---SEKEKRTTEHKVKNLTEEVEFLN 1008
Query: 179 EKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPER 238
E + + R + TL + + S + + N LK ++ E
Sbjct: 1009 EDISKLNRAAKVVQEAHQQTLDDLHMEEEKLSSLSKAN------------LKLEQQVDEL 1056
Query: 239 GG--DEKQMALLN-QRISQLAENNISLKSE-IERLKASVIRTEESALANEKRLQEKMHEC 294
G ++++ A +N +R E N+ L E +E L++S + LA E L++K E
Sbjct: 1057 EGALEQERKARMNCERELHKLEGNLKLNRESMENLESS-----QRHLAEE--LRKKELEL 1109
Query: 295 AQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREEL 354
+Q+ +++ + ++ LQ+ TV++ LQT + +L+ +L A R + E+ER +L
Sbjct: 1110 SQMNSKVENEKGLVAQ-LQK------TVKE-LQTQIKDLKEKLEAERTTRAKMERERADL 1161
Query: 355 KNRLHWQMKRLTE--NFEQAQLRILGLQ-TQVQSLRR 388
L +RL E AQL I Q T++Q L R
Sbjct: 1162 TQDLADLNERLEEVGGSSLAQLEITKKQETKIQKLHR 1198
Score = 31.9 bits (69), Expect = 4.3
Identities = 29/146 (19%), Positives = 65/146 (44%), Gaps = 5/146 (3%)
Query: 241 DEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGE 300
+++ +A + ++ L ++ I L++ ++ L V EE R ++ EC +L E
Sbjct: 916 EQETLANVEEQCEWLIKSKIQLEARVKELSERVEEEEEINSELTARGRKLEDECFELKKE 975
Query: 301 LDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHW 360
+D ++ ++ TE K L V L ++ ++ ++ + LH
Sbjct: 976 IDDLETMLVKS-EKEKRTTEHKVKNLTEEVEFLNEDISKLNRAAKVVQEAHQQTLDDLHM 1034
Query: 361 QMKRLTENFEQAQLRILGLQTQVQSL 386
+ ++L+ + +A L+ L+ QV L
Sbjct: 1035 EEEKLS-SLSKANLK---LEQQVDEL 1056
>D00943-1|BAA00791.1| 1939|Homo sapiens cardiac alpha-myosin heavy
chain protein.
Length = 1939
Score = 44.8 bits (101), Expect = 6e-04
Identities = 63/312 (20%), Positives = 127/312 (40%), Gaps = 18/312 (5%)
Query: 61 LKQCYREAREEIDELRTLMKEQNDQLQDYRVKY----LQAQQLVEEQRRQXXXXXXXNTR 116
L++ Y E E EL+ ++ + N ++ R KY +Q + +EE +++
Sbjct: 1345 LREQYEEETEAKAELQRVLSKANSEVAQCRTKYETDAIQRTEELEEAKKKLAQRLQDAEE 1404
Query: 117 ISEQINLE---IQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQ--AQAIAE--HNAEQ 169
E +N + +++ K + Q ++++L + A L Q+ + +AE E+
Sbjct: 1405 AVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEE 1464
Query: 170 LARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSL 229
EL ++++ + L+ L +L + F + + D T L
Sbjct: 1465 SQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLT-EQLGEGGK 1523
Query: 230 KPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQE 289
E R E + L S L E SL+ E ++ + + + E++L E
Sbjct: 1524 NVHELEKVRKQLEVEKLELQ---SALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAE 1580
Query: 290 KMHECAQLGGELDRTRDEASRALQ---RAHEQTETVRKCLQTTVAELERQLAASRAQVST 346
K E Q R D +L R+ + V+K ++ + E+E QL+ + +
Sbjct: 1581 KDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAE 1640
Query: 347 AEKEREELKNRL 358
A+K+ + L++ L
Sbjct: 1641 AQKQVKSLQSLL 1652
Score = 39.9 bits (89), Expect = 0.016
Identities = 32/159 (20%), Positives = 65/159 (40%), Gaps = 3/159 (1%)
Query: 237 ERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQ 296
E G +Q+ ISQL +S ++E LK + ++ A LQ H+C
Sbjct: 1285 ENGELSRQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDL 1344
Query: 297 LGGELD---RTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREE 353
L + + + E R L +A+ + R +T + +L ++ +++ ++ EE
Sbjct: 1345 LREQYEEETEAKAELQRVLSKANSEVAQCRTKYETDAIQRTEELEEAKKKLAQRLQDAEE 1404
Query: 354 LKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRRTASS 392
++ + L + + Q I L V+ A++
Sbjct: 1405 AVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAA 1443
Score = 39.5 bits (88), Expect = 0.021
Identities = 76/403 (18%), Positives = 169/403 (41%), Gaps = 50/403 (12%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTL 78
++ E+Q++L + + L+T L + E++ E ++ K+ + +EEI +L
Sbjct: 1461 KYEESQSELESSQKEARSLSTELFKLKNAYEESLE---HLETFKRENKNLQEEISDLTEQ 1517
Query: 79 MKEQNDQLQDYRV--KYLQAQQL-VEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEK 135
+ E + + K L+ ++L ++ + + LE ++K + + K
Sbjct: 1518 LGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERK 1577
Query: 136 LQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVT 195
L E + K R+ D+ Q AE + R +V+ + + +
Sbjct: 1578 LAEKDEEMEQAKRNHQRVVDSLQTSLDAETRS----------RNEVLRVKKKMEGDLNEM 1627
Query: 196 TMTLTQED-LFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQ 254
+ L+ + + ++Q ++ +++ LL ++ + D K+ + +R
Sbjct: 1628 EIQLSHANRMAAEAQKQV------KSLQSLLKDTQIQLDDAVRANDDLKENIAIVER--- 1678
Query: 255 LAENNISLKSEIERLKASVIRTEESALANEKRLQEK--------------MHECAQLGGE 300
NN+ L++E+E L+A V +TE S ++ L E +++ ++ +
Sbjct: 1679 --RNNL-LQAELEELRAVVEQTERSRKLADRELIETSERVQLLHSQNTSLINQKKKMDAD 1735
Query: 301 LDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHW 360
L + + E A+Q E +K + T A + +L + Q ++A ER +K +
Sbjct: 1736 LSQLQSEVEEAVQECRNAEEKAKKAI-THAAMMAEEL--KKEQDTSAHLER--MKKNMEQ 1790
Query: 361 QMKRLTENFEQA-QLRILGLQTQVQSLR-RTASSTGDGDGENQ 401
+K L ++A Q+ + G + Q+Q L R G+ + E +
Sbjct: 1791 TIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGELEAEQK 1833
Score = 37.1 bits (82), Expect = 0.11
Identities = 72/358 (20%), Positives = 143/358 (39%), Gaps = 20/358 (5%)
Query: 23 TQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQ 82
T+NK++ L + GL L +KE+ QE + +AL E ++++ L +
Sbjct: 973 TENKVKNLTEEMAGLDEIIAKL--TKEKKALQEAHQQALDDLQAE-EDKVNTLSKSKVKL 1029
Query: 83 NDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKL------ 136
Q+ D L+ ++ V + + +++++ ++++ KL+ +EKL
Sbjct: 1030 EQQVDDLEGS-LEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFD 1088
Query: 137 --QELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLV 194
Q+ + I D K ++ QA E E+L E AR KV + R S L
Sbjct: 1089 INQQNSKIEDEQVLALQLQKKLKENQARIEELEEELEAE-RTARAKVEKL-RSDLSREL- 1145
Query: 195 TTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGD--EKQMALLNQRI 252
++ E+ G + +I K + + L+ E K+ A +
Sbjct: 1146 EEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAEL 1205
Query: 253 SQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRAL 312
+ +N +K ++E+ K+ + +N +++ + ++ L+ +E L
Sbjct: 1206 GEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKL 1265
Query: 313 QRAHEQTE---TVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTE 367
+ A T R LQT EL RQL A +S + + ++ ++L E
Sbjct: 1266 EEAQRSLNDFTTQRAKLQTENGELSRQLEEKEALISQLTRGKLSYTQQMEDLKRQLEE 1323
>BC040232-1|AAH40232.1| 696|Homo sapiens CCDC88 protein protein.
Length = 696
Score = 44.8 bits (101), Expect = 6e-04
Identities = 90/382 (23%), Positives = 160/382 (41%), Gaps = 36/382 (9%)
Query: 21 RETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQ----EVNVRALKQCYREAREE-IDEL 75
+E +L L+ + E A + KE ++ E + A Q ++EE + EL
Sbjct: 18 KELGARLEHLQRELEQAALERQEFLREKESQHQRYQGLEQRLEAELQAAATSKEEALMEL 77
Query: 76 RTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISE--QINLEIQRVKLKFQ 133
+T + ++L ++++ A L ++R + N R+ E + N + K Q
Sbjct: 78 KTRALQLEEEL--FQLRQGPAG-LGPKKRAEPQLVETQNVRLIEVERSNAMLVAEKAALQ 134
Query: 134 EKLQEL-APIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLY 192
+LQ L + L Q L +Q+AQ EH++ +L E + + + R L L
Sbjct: 135 GQLQHLEGQLGSLQGRAQELLLQSQRAQ---EHSS-RLQAEKSVLEIQGQELHRKLEVLE 190
Query: 193 L-VTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQR 251
V +QE+ GQ Q+ + +D H L + E E + N R
Sbjct: 191 EEVRAARQSQEETRGQQQALL----RD---HKALAQLQRRQEAELEGLLVRHRDLKANMR 243
Query: 252 ISQLAENNISLKSE-IERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASR 310
+LA + + E ++ +ASV E + LA +RL + H R +E R
Sbjct: 244 ALELAHRELQGRHEQLQAQRASVEAQEVALLAERERLMQDGHR--------QRGLEEELR 295
Query: 311 ALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFE 370
LQ H++ + + L EL+ + R +++ E ER +L+ Q ++L E+ +
Sbjct: 296 RLQSEHDRAQMLLAELSRERGELQGERGELRGRLARLELERAQLE----MQSQQLRESNQ 351
Query: 371 QAQLRILGLQTQVQSLRRTASS 392
Q L L TQ + L + S+
Sbjct: 352 QLDLSACRLTTQCELLTQLRSA 373
Score = 31.9 bits (69), Expect = 4.3
Identities = 41/166 (24%), Positives = 72/166 (43%), Gaps = 13/166 (7%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTL 78
+HR+ + +R LE+ H L G EQ Q +V A + RE + +
Sbjct: 234 RHRDLKANMRALEL------AHRE-LQGRHEQLQAQRASVEAQEVALLAERERLMQDGHR 286
Query: 79 MKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQI-NLEIQRVKLKFQ-EKL 136
+ ++L+ + ++ +AQ L+ E R+ + ++ LE++R +L+ Q ++L
Sbjct: 287 QRGLEEELRRLQSEHDRAQMLLAELSRERGELQGERGELRGRLARLELERAQLEMQSQQL 346
Query: 137 QELAPIPDLLK---ATQMRLKDAQQAQAIAEHNAEQLARELNCARE 179
+E DL TQ L Q A E N + LA +RE
Sbjct: 347 RESNQQLDLSACRLTTQCELL-TQLRSAQEEENRQLLAEVQALSRE 391
>BC032853-1|AAH32853.1| 767|Homo sapiens golgi autoantigen, golgin
subfamily a, 1 protein.
Length = 767
Score = 44.8 bits (101), Expect = 6e-04
Identities = 75/380 (19%), Positives = 155/380 (40%), Gaps = 36/380 (9%)
Query: 26 KLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQ 85
K +E K + L N+L ++ Q +N+ + R+E+DEL Q +
Sbjct: 131 KDQEWSEKMDQLEKEKNILTAQLQEMKNQSMNLF-------QRRDEMDELEGF---QQQE 180
Query: 86 LQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDL 145
L + L+ ++ + + ++ +R E++ + ++ +KL+EL
Sbjct: 181 LSKIKHMLLKKEESLGKMEQELEARTRELSRTQEEL-MNSNQMSSDLSQKLEEL------ 233
Query: 146 LKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYL-YSLYLVTTMTLTQEDL 204
+ L++ + ++ AE L +++ + + L L VT T +ED+
Sbjct: 234 -QRHYSTLEEQRDHVIASKTGAESKITALEQKEQELQALIQQLSIDLQKVTAETQEKEDV 292
Query: 205 FGQSQSEIGRGNK--DQTVHVLLHNSLKPPEKP-PERGGDEKQMALLNQRISQLAENNIS 261
Q ++ K +Q + H EK E+ ++ + LL R SQ N +
Sbjct: 293 ITHLQEKVASLEKRLEQNLSGEEHVQELLKEKTLAEQNLEDTRQQLLAARSSQAKAIN-T 351
Query: 262 LKSEIERLKASVIRTEES-------ALANEKRLQE------KMHECAQLGGELDRTRDEA 308
L++ + L+ ++ +EE A E ++QE + Q L++ E
Sbjct: 352 LETRVRELEQTLQASEEQLQQSKGIVAAQETQIQELAAANQESSHVQQQALALEQQFLER 411
Query: 309 SRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTEN 368
++AL+ E +R QTT + RQL A + E E +++K+L E
Sbjct: 412 TQALEAQIVALERMRAADQTTAEQGMRQLEQENAALKECRNEYERSLQNHQFELKKLKEE 471
Query: 369 FEQAQLRILGLQTQVQSLRR 388
+ Q ++ + + ++ +R+
Sbjct: 472 WSQREIVSVAMAQALEEVRK 491
Score = 31.1 bits (67), Expect = 7.4
Identities = 76/371 (20%), Positives = 141/371 (38%), Gaps = 32/371 (8%)
Query: 24 QNKLRELEMKFEGLAT---HTNMLMGSKEQAFEQEVNVRALKQCYREAREE-IDELRTLM 79
Q K+ LE + E + H L+ K A + + R R ++ + I+ L T +
Sbjct: 297 QEKVASLEKRLEQNLSGEEHVQELLKEKTLAEQNLEDTRQQLLAARSSQAKAINTLETRV 356
Query: 80 KEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQEL 139
+E LQ + Q++ +V Q Q N S + + ++ +F E+ Q L
Sbjct: 357 RELEQTLQASEEQLQQSKGIVAAQETQIQELAAANQE-SSHVQQQALALEQQFLERTQAL 415
Query: 140 APIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTL 199
++ +MR D A+ ++ A C E + + + L +
Sbjct: 416 EA--QIVALERMRAADQTTAEQGMRQLEQENAALKECRNEYERSLQNHQFELKKLKEEWS 473
Query: 200 TQEDL---FGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLN--QRISQ 254
+E + Q+ E+ R +++ + + EK E+ EK LL Q I Q
Sbjct: 474 QREIVSVAMAQALEEV-RKQREEFQQQAANLTAIIDEK--EQNLREKTEVLLQKEQEILQ 530
Query: 255 LAENNISLKSEIERLKASV-----IRTEESALANEKRLQEKMHECAQLGGELDRTRDEAS 309
L + S +I +L+A + ++ EE+A+ E+ ++ Q S
Sbjct: 531 LERGHNSALLQIHQLQAELEALRTLKAEEAAVVAEQEDLLRLRGPLQAEALSVNESHVTS 590
Query: 310 RALQRAHEQTETVRKC------------LQTTVAELERQLAASRAQVSTAEKEREELKNR 357
RA+Q Q T + LQ +LE+QL + ++ EL+
Sbjct: 591 RAMQDPVFQLPTAGRTPNGEVGAMDLTQLQKEKQDLEQQLLEKNKTIKQMQQRMLELRKT 650
Query: 358 LHWQMKRLTEN 368
L ++K +N
Sbjct: 651 LQKELKIRPDN 661
>AY651261-1|AAX35689.1| 1244|Homo sapiens centrosomal protein 1
protein.
Length = 1244
Score = 44.8 bits (101), Expect = 6e-04
Identities = 76/357 (21%), Positives = 147/357 (41%), Gaps = 29/357 (8%)
Query: 19 QHRETQNKLRELEMKFEGLAT---HTNMLMGSKEQAFEQEV-----NVRALKQCYREARE 70
+H +N++ LE + L + + SK Q+ E+E+ N+ L Q +
Sbjct: 884 EHHNLENEVSRLEDIMQHLKSKKREERWMRASKRQS-EKEMEELHHNIDDLLQEKKSLEC 942
Query: 71 EIDEL-RTLMKEQNDQ-LQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQI---NLEI 125
E++EL RT+ K Q + D V+ L + +E+ + I + + E+
Sbjct: 943 EVEELHRTVQKRQQQKDFIDGNVESLMTELEIEKSLKHHEDIVDEIECIEKTLLKRRSEL 1002
Query: 126 QRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIF 185
+ E EL+ + K + DA+++ E +AE+L R +V
Sbjct: 1003 READRLLAEAESELSCTKEKTKNAVEKFTDAKRSLLQTESDAEELERRAQETAVNLVKAD 1062
Query: 186 RYLYSLYL----VTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGD 241
+ L SL + + QE++ + + KD L K E+ + D
Sbjct: 1063 QQLRSLQADAKDLEQHKIKQEEILKEINKIVAA--KDSDFQCLSKKKEKLTEELQKLQKD 1120
Query: 242 EKQMALLNQ--RISQLAENNISL---KSEIERLKASVIRTEESALANEKRLQEKMHECAQ 296
+MA N+ + L E+ + L ++E+E+LK+ V ++ +++L K E
Sbjct: 1121 I-EMAERNEDHHLQVLKESEVLLQAKRAELEKLKSQVTSQQQEMAVLDRQLGHKKEELHL 1179
Query: 297 LGGELDRTRDEASRALQRAHEQTETVRKCLQ-TTVAELERQLAASRAQVSTAEKERE 352
L G + + + + AL+ +TE KC V L +L+ + +++ ER+
Sbjct: 1180 LQGSMVQAKADLQEALRLG--ETEVTEKCNHIREVKSLLEELSFQKGELNVQISERK 1234
Score = 32.3 bits (70), Expect = 3.2
Identities = 37/142 (26%), Positives = 70/142 (49%), Gaps = 18/142 (12%)
Query: 241 DEKQMALLNQRISQLAENNISLKSEIERLKASVIRTE----ESALANEKR----LQEKMH 292
DEK+ L QR++++ + L EI + A +R E ESAL + LQ+
Sbjct: 211 DEKETLL--QRLTEVEQERDQL--EIVAMDAENMRKELAELESALQEQHEVNASLQQTQG 266
Query: 293 ECAQLGGELD---RTRDEASRALQRAHEQTETVRKCLQTTV-AELERQLAASRAQVSTAE 348
+ + EL+ RD + L+ E+ + + Q+ + AELE++ A + + A+
Sbjct: 267 DLSAYEAELEARLNLRDAEANQLKEELEKVTRLTQLEQSALQAELEKERQALKNALGKAQ 326
Query: 349 --KEREELKNRLHWQMKRLTEN 368
+E+E+ + LH ++K L ++
Sbjct: 327 FSEEKEQENSELHAKLKHLQDD 348
>AB209115-1|BAD92352.1| 1065|Homo sapiens restin isoform a variant
protein.
Length = 1065
Score = 44.8 bits (101), Expect = 6e-04
Identities = 79/394 (20%), Positives = 174/394 (44%), Gaps = 35/394 (8%)
Query: 22 ETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVN-VRALKQCYREAREEIDELRTLMK 80
+T NKL+E E+K E A + + S +++ ++ VN + ++ + ++++LR +
Sbjct: 470 DTLNKLQEAEIKKEKFAEASEEAV-SVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLA 528
Query: 81 EQNDQL--QDYRVKYL-QAQQLVEEQRRQXXXXXXXN----TRISEQINL---EIQRVKL 130
+ + +D R + L +A++ +E + N T++++++ L +++ ++L
Sbjct: 529 DMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQL 588
Query: 131 KFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAE--QLARELNCAREKVVHIFRYL 188
K + + + + ++ ++ + +QQ +A +H E +L R+L+ +K+
Sbjct: 589 KLTKANENASFLQKSIEDMTVKAEQSQQ-EAAKKHEEEKKELERKLSDLEKKMETSHNQC 647
Query: 189 YSLYL----VTTMTLTQ-EDLFGQSQSEI------GRGNKDQTVHVL--LHNSLKPPEKP 235
L T+ T T+ E++ Q + +G +++ +L L K EK
Sbjct: 648 QELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQAEKA 707
Query: 236 PERGGDEKQMALLNQRISQLAENNISL---KSEIERLKASVIRTEESALANEKRLQEKMH 292
E M ++ Q + E SL K +L+ + +E+ L N + L +
Sbjct: 708 KAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKSKE 767
Query: 293 ECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVST---AEK 349
+++ R E Q A ++++ + LQ +L +L SR +V++ E+
Sbjct: 768 LLTVENQKMEEFRKEIETLKQAAAQKSQQL-SALQEENVKLAEELGRSRDEVTSHQKLEE 826
Query: 350 EREELKNRLHWQMKRLTENFEQAQLRILGLQTQV 383
ER L N+L KR ++ + A LQ +
Sbjct: 827 ERSVLNNQLLEMKKRESKFIKDADEEKASLQKSI 860
Score = 37.1 bits (82), Expect = 0.11
Identities = 28/92 (30%), Positives = 43/92 (46%), Gaps = 4/92 (4%)
Query: 282 ANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHE---QTETVRKCLQTTVAELERQLA 338
A ++ L+EK QL E D R E ++A E + R V ELE ++
Sbjct: 103 ALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALARDGHDQHVLELEAKMD 162
Query: 339 ASRAQVSTAEKEREELKNRLHWQMKRLTENFE 370
R V A++E+ EL N+L + KR E+ +
Sbjct: 163 QLRTMVEAADREKVELLNQLE-EEKRKVEDLQ 193
Score = 36.3 bits (80), Expect = 0.20
Identities = 66/317 (20%), Positives = 128/317 (40%), Gaps = 22/317 (6%)
Query: 67 EAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQ 126
E ++D+LRT+++ + + + + + ++ VE+ + + + Q LE
Sbjct: 156 ELEAKMDQLRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLETQTKLEHA 215
Query: 127 RVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFR 186
R+K Q L E L Q L+D + A + +L ++L ++V + R
Sbjct: 216 RIKELEQSLLFEKTKADKL----QRELEDTRVATVSEKSRIMELEKDLALRVQEVAELRR 271
Query: 187 YLYSLY----LVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDE 242
L S + +++L QE Q + E+ R + + + SLK E +
Sbjct: 272 RLESNKPAGDVDMSLSLLQEISSLQEKLEVTRTDHQREI-----TSLKEHFGAREE-THQ 325
Query: 243 KQMALLNQRISQLAENNISLKSEIE---RLKASVIRTEESALANEKRLQEKMHECAQLGG 299
K++ L +L++ N SLKS++E + + VI +S L E + +L
Sbjct: 326 KEIKALYTATEKLSKENESLKSKLEHANKENSDVIALWKSKL--ETAIASHQQAMEELKV 383
Query: 300 ELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLH 359
+ + Q E +R Q + L+ Q + RA KE E L+ +L
Sbjct: 384 SFSKGLGTETAEFAELKTQIEKMRLDYQHEIENLQNQQDSERA---AHAKEMEALRAKLM 440
Query: 360 WQMKRLTENFEQAQLRI 376
+K + E + ++
Sbjct: 441 KVIKEKENSLEAIRSKL 457
Score = 36.3 bits (80), Expect = 0.20
Identities = 65/318 (20%), Positives = 129/318 (40%), Gaps = 41/318 (12%)
Query: 66 REAREEIDELRTLMKEQNDQ-------LQDYRVKYLQAQQLV----EEQRRQXXXXXXXN 114
R +++EL+ + + N+ ++D VK Q+QQ EE++++
Sbjct: 577 RLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDL 636
Query: 115 TRISEQINLEIQRVKLKFQEKLQEL-APIPDLLKATQMRLKDAQQAQAIAEHNAEQLARE 173
+ E + + Q +K +++ E ++L+ Q L D + A L +E
Sbjct: 637 EKKMETSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQE 696
Query: 174 LNCAR---EKVVHIFRYLYSLYLVTTMTLTQ-EDLFGQSQSEIGRGNKDQTVHVLLHNSL 229
L R EK ++ ++ MT + E L ++ + L N+L
Sbjct: 697 LEELRKQAEKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKENNL 756
Query: 230 KPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQE 289
K E E ++ + + NQ++ + + EIE LK ++A ++L
Sbjct: 757 KNVE---ELNKSKELLTVENQKMEEF-------RKEIETLK-------QAAAQKSQQLSA 799
Query: 290 KMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEK 349
E +L EL R+RDE + +H++ E R L + E++++ + A++
Sbjct: 800 LQEENVKLAEELGRSRDEVT-----SHQKLEEERSVLNNQLLEMKKR---ESKFIKDADE 851
Query: 350 EREELKNRLHWQMKRLTE 367
E+ L+ + LTE
Sbjct: 852 EKASLQKSISITSALLTE 869
>Z38133-1|CAA86293.1| 1937|Homo sapiens Myosin protein.
Length = 1937
Score = 44.4 bits (100), Expect = 7e-04
Identities = 75/372 (20%), Positives = 151/372 (40%), Gaps = 21/372 (5%)
Query: 24 QNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQN 83
Q ++LE + L T+ L + E + + N+ K C R +++ EL+T +EQ
Sbjct: 1214 QRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLE--KMC-RSLEDQVSELKTKEEEQQ 1270
Query: 84 DQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIP 143
+ D + + Q E RQ +++S Q+++ + + +L+E
Sbjct: 1271 RLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIE-ELKHQLEEETKAK 1329
Query: 144 D-LLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQE 202
+ L A Q D + E E A EL A K + Y + T+E
Sbjct: 1330 NALAHALQSSRHDCDLLREQYEEEQEGKA-ELQRALSKANSEVAQWRTKYETDAIQRTEE 1388
Query: 203 DLFGQSQSEIGRGNKDQTVHVLLHNS-LKPPEKPPERGGDEKQMALLNQRISQLAENNIS 261
+++ ++ + ++ HV N+ EK +R +E + +L+ S A +
Sbjct: 1389 --LEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAA--CAA 1444
Query: 262 LKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTET 321
L + + ++ + L+ E L EL + ++ +L +Q ET
Sbjct: 1445 LDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESL----DQLET 1500
Query: 322 VR---KCLQTTVAELERQLAASRAQVSTAE---KEREELKNRLHWQMKRLTENFEQAQLR 375
+R K LQ +++L Q+A Q+ E K+ E+ K + ++ + E + +
Sbjct: 1501 LRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGK 1560
Query: 376 ILGLQTQVQSLR 387
IL +Q ++ ++
Sbjct: 1561 ILRIQLELNQVK 1572
Score = 44.4 bits (100), Expect = 7e-04
Identities = 69/382 (18%), Positives = 153/382 (40%), Gaps = 19/382 (4%)
Query: 25 NKLRELEMKFEGLATHTNMLMGSKEQAFE-QEVNVRALKQCYREAREEIDELRTLMKEQN 83
++L +++ + E + E + E +E + ++ + + E+D E+
Sbjct: 1527 HELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEI 1586
Query: 84 DQLQDYRVKYLQAQQ-LVEEQRRQXXXXXXXNTRISEQIN-LEIQ--RVKLKFQEKLQEL 139
DQL+ + ++ Q ++ + R ++ +N +EIQ E L+
Sbjct: 1587 DQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLRNY 1646
Query: 140 APIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTL 199
+LK TQ+ L DA + Q + + R N + ++ ++ L + +
Sbjct: 1647 RNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQ--TERSRKI 1704
Query: 200 TQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENN 259
+++L S+ R T + L N+ K E + E + + + S+ AE
Sbjct: 1705 AEQELLDASE----RVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVI---QESRNAEEK 1757
Query: 260 ISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASR-ALQRAHEQ 318
+ A ++ E+ A+ +R+++ + + + +L DEA + AL+ +Q
Sbjct: 1758 AKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVK---DLQHRLDEAEQLALKGGKKQ 1814
Query: 319 TETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQLRILG 378
+ + ++ E+E + + V K +K L +Q + +N + Q +
Sbjct: 1815 IQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVK-ELTYQTEEDRKNVLRLQDLVDK 1873
Query: 379 LQTQVQSLRRTASSTGDGDGEN 400
LQ +V+S +R A + N
Sbjct: 1874 LQAKVKSYKRQAEEAEEQSNAN 1895
Score = 33.1 bits (72), Expect = 1.8
Identities = 70/329 (21%), Positives = 128/329 (38%), Gaps = 31/329 (9%)
Query: 49 EQAFEQEVNVRA-LKQCYREAREEID---ELRTLMKEQNDQLQDYRVKYLQAQ-QLVEEQ 103
EQ + ++ + A +K+ A EE + EL ++ D+ + + + L + +
Sbjct: 909 EQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 968
Query: 104 RRQXXXXXXXNTRISEQINLEIQRVKLKFQEK-LQEL-APIPDLLKATQMRLKDAQQAQA 161
+ + E L+ KL ++K LQE D L+A + ++ +A+
Sbjct: 969 KEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNILTKAKT 1028
Query: 162 IAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTV 221
E + L L +EK + + L + L QE + K +
Sbjct: 1029 KLEQQVDDLEGSLE--QEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKK 1086
Query: 222 HVLLHNSLKPPEKPPERGGDEKQMAL-LNQRISQLAENNISLKSEIERLKASVIRTEESA 280
+ N + E DE+ + + L ++I +L L EIE +AS + E+
Sbjct: 1087 EFEISNLISKIE-------DEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQR 1139
Query: 281 LANEKRLQEKMHECAQLGG------ELDRTRDEASRALQR-------AHE-QTETVRKCL 326
+ L+E + GG EL++ R+ + L+R HE +RK
Sbjct: 1140 SDLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKH 1199
Query: 327 QTTVAELERQLAASRAQVSTAEKEREELK 355
++AEL Q+ + EKE+ ELK
Sbjct: 1200 ADSMAELGEQIDNLQRVKQKLEKEKSELK 1228
>X51592-1|CAA35941.1| 1437|Homo sapiens fetal-myosin heavy chain (1437
AA) protein.
Length = 1437
Score = 44.4 bits (100), Expect = 7e-04
Identities = 69/382 (18%), Positives = 153/382 (40%), Gaps = 19/382 (4%)
Query: 25 NKLRELEMKFEGLATHTNMLMGSKEQAFE-QEVNVRALKQCYREAREEIDELRTLMKEQN 83
++L +++ + E + E + E +E + ++ + + E+D E+
Sbjct: 1027 HELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEI 1086
Query: 84 DQLQDYRVKYLQAQQ-LVEEQRRQXXXXXXXNTRISEQIN-LEIQ--RVKLKFQEKLQEL 139
DQL+ + ++ Q ++ + R ++ +N +EIQ E L+
Sbjct: 1087 DQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLRNY 1146
Query: 140 APIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTL 199
+LK TQ+ L DA + Q + + R N + ++ ++ L + +
Sbjct: 1147 RNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQ--TERSRKI 1204
Query: 200 TQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENN 259
+++L S+ R T + L N+ K E + E + + + S+ AE
Sbjct: 1205 AEQELLDASE----RVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVI---QESRNAEEK 1257
Query: 260 ISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASR-ALQRAHEQ 318
+ A ++ E+ A+ +R+++ + + + +L DEA + AL+ +Q
Sbjct: 1258 AKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVK---DLQHRLDEAEQLALKGGKKQ 1314
Query: 319 TETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQLRILG 378
+ + ++ E+E + + V K +K L +Q + +N + Q +
Sbjct: 1315 IQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVK-ELTYQTEEDRKNVLRLQDLVDK 1373
Query: 379 LQTQVQSLRRTASSTGDGDGEN 400
LQ +V+S +R A + N
Sbjct: 1374 LQAKVKSYKRQAEEAEEQSNAN 1395
Score = 39.9 bits (89), Expect = 0.016
Identities = 31/151 (20%), Positives = 67/151 (44%), Gaps = 3/151 (1%)
Query: 237 ERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQ 296
E G +Q+ + +SQL+ + + +IE LK + ++ A LQ H+C
Sbjct: 786 EAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDL 845
Query: 297 LGGELDRTRD---EASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREE 353
L + + ++ E RAL +A+ + R +T + +L ++ +++ +E EE
Sbjct: 846 LREQYEEEQEGKAELQRALSKANSEVAQWRTNTETDAIQRTEELEEAKKKLAQRLQEAEE 905
Query: 354 LKNRLHWQMKRLTENFEQAQLRILGLQTQVQ 384
++ + L + ++ Q + L V+
Sbjct: 906 HVEAVNAKCASLEKTKQRLQNEVEDLMLDVE 936
Score = 39.5 bits (88), Expect = 0.021
Identities = 74/375 (19%), Positives = 152/375 (40%), Gaps = 26/375 (6%)
Query: 24 QNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQN 83
Q ++LE + L T+ L + E + + N+ K R +++ EL+T +EQ
Sbjct: 713 QRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLE--KDGGRSLEDQVSELKTKEEEQQ 770
Query: 84 DQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIP 143
+ D + + Q E RQ +++S Q+++ + + +L+E
Sbjct: 771 RLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIE-ELKHQLEEETKAK 829
Query: 144 D-LLKATQMRLKDAQQAQAIAEHNAE---QLARELNCAREKVVHIFRYLYSLYLVTTMTL 199
+ L A Q D + E E +L R L+ A +V + T
Sbjct: 830 NALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQ-----WRTNTETDAIQ 884
Query: 200 TQEDLFGQSQSEIGRGNKDQTVHVLLHNS-LKPPEKPPERGGDEKQMALLNQRISQLAEN 258
E+L +++ ++ + ++ HV N+ EK +R +E + +L+ S A
Sbjct: 885 RTEEL-EEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAA-- 941
Query: 259 NISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQ 318
+L + + ++ + L+ E L EL + ++ +L +Q
Sbjct: 942 CAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESL----DQ 997
Query: 319 TETVR---KCLQTTVAELERQLAASRAQVSTAE---KEREELKNRLHWQMKRLTENFEQA 372
ET+R K LQ +++L Q+A Q+ E K+ E+ K + ++ + E
Sbjct: 998 LETLRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHE 1057
Query: 373 QLRILGLQTQVQSLR 387
+ +IL +Q ++ ++
Sbjct: 1058 EGKILRIQLELNQVK 1072
Score = 33.1 bits (72), Expect = 1.8
Identities = 70/329 (21%), Positives = 128/329 (38%), Gaps = 31/329 (9%)
Query: 49 EQAFEQEVNVRA-LKQCYREAREEID---ELRTLMKEQNDQLQDYRVKYLQAQ-QLVEEQ 103
EQ + ++ + A +K+ A EE + EL ++ D+ + + + L + +
Sbjct: 408 EQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 467
Query: 104 RRQXXXXXXXNTRISEQINLEIQRVKLKFQEK-LQEL-APIPDLLKATQMRLKDAQQAQA 161
+ + E L+ KL ++K LQE D L+A + ++ +A+
Sbjct: 468 KEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNILTKAKT 527
Query: 162 IAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTV 221
E + L L +EK + + L + L QE + K +
Sbjct: 528 KLEQQVDDLEGSLE--QEKKLRMDLERAKRKLEGDLKLAQESTMDNENDKQQLDEKLEKK 585
Query: 222 HVLLHNSLKPPEKPPERGGDEKQMAL-LNQRISQLAENNISLKSEIERLKASVIRTEESA 280
+ N + E DE+ + + L ++I +L L EIE +AS + E+
Sbjct: 586 EFEISNLISKIE-------DEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQR 638
Query: 281 LANEKRLQEKMHECAQLGG------ELDRTRDEASRALQR-------AHE-QTETVRKCL 326
+ L+E + GG EL++ R+ + L+R HE +RK
Sbjct: 639 SDLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKH 698
Query: 327 QTTVAELERQLAASRAQVSTAEKEREELK 355
++AEL Q+ + EKE+ ELK
Sbjct: 699 ADSMAELGEQIDNLQRVKQKLEKEKSELK 727
>U51587-1|AAB81549.1| 767|Homo sapiens Golgi complex autoantigen
golgin-97 protein.
Length = 767
Score = 44.4 bits (100), Expect = 7e-04
Identities = 75/380 (19%), Positives = 154/380 (40%), Gaps = 36/380 (9%)
Query: 26 KLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQ 85
K +E K + L N+L ++ Q +N+ + R+E+DEL Q +
Sbjct: 131 KDQEWSEKMDQLEKEKNILTAQLQEMKNQSMNLF-------QRRDEMDELEGF---QQQE 180
Query: 86 LQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDL 145
L + L+ ++ + + ++ +R E++ + ++ +KL+EL
Sbjct: 181 LSKIKHMLLKKEESLGKMEQELEARTRELSRTQEEL-MNSNQMSSDLSQKLEEL------ 233
Query: 146 LKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYL-YSLYLVTTMTLTQEDL 204
+ L++ + ++ AE L +++ + + L L VT T +ED+
Sbjct: 234 -QRHYSTLEEQRDHVIASKTGAESKITALEQKEQELQALIQQLSIDLQKVTAETQEKEDV 292
Query: 205 FGQSQSEIGRGNK--DQTVHVLLHNSLKPPEKP-PERGGDEKQMALLNQRISQLAENNIS 261
Q ++ K +Q + H EK E+ ++ + LL R SQ N +
Sbjct: 293 ITHLQEKVASLEKRLEQNLSGEEHVQELLKEKTLAEQNLEDTRQQLLAARSSQAKAIN-T 351
Query: 262 LKSEIERLKASVIRTEES-------ALANEKRLQE------KMHECAQLGGELDRTRDEA 308
L++ + L+ ++ +EE A E ++QE + Q L++ E
Sbjct: 352 LETRVRELEQTLQASEEQLQQSKGIVAAQETQIQELAAANQESSHVQQQALALEQQFLER 411
Query: 309 SRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTEN 368
++AL+ E R QTT + RQL A + E E +++K+L E
Sbjct: 412 TQALEAQIVALERTRAADQTTAEQGMRQLEQENAALKECRNEYERSLQNHQFELKKLKEE 471
Query: 369 FEQAQLRILGLQTQVQSLRR 388
+ Q ++ + + ++ +R+
Sbjct: 472 WSQREIVSVAMAQALEEVRK 491
Score = 31.1 bits (67), Expect = 7.4
Identities = 27/117 (23%), Positives = 47/117 (40%), Gaps = 1/117 (0%)
Query: 49 EQAFEQ-EVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQX 107
EQ Q E ALK+C E + + +K+ ++ + + Q +EE R+Q
Sbjct: 434 EQGMRQLEQENAALKECRNEYERSLQNHQFELKKLKEEWSQREIVSVAMAQALEEVRKQR 493
Query: 108 XXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAE 164
++ I+ + Q ++ K + LQ+ I L + L Q QA E
Sbjct: 494 EEFQQQAANLTAIIDEKEQNLREKTEVLLQKEQEILQLERGHNSALLQIHQLQAELE 550
>BC125086-1|AAI25087.1| 634|Homo sapiens CCDC41 protein protein.
Length = 634
Score = 44.4 bits (100), Expect = 7e-04
Identities = 66/351 (18%), Positives = 137/351 (39%), Gaps = 13/351 (3%)
Query: 50 QAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXX 109
Q E + VR+L+ + A + L ++ ++Q K +A++ + +
Sbjct: 247 QLAEMQATVRSLEAEKQSANLRAERLEKELQSSSEQNTFLINKLHKAEREINTLSSKVKE 306
Query: 110 XXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDA-QQAQAIAEHNAE 168
N I LE R K + + + ++ D L++ LK A + + +
Sbjct: 307 LKHSNKLEITDIKLETARAKSELERERNKIQSELDGLQSDNEILKAAVEHHKVLLVEKDR 366
Query: 169 QLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVL---- 224
+L R++ A+E+ L L L + + KDQ L
Sbjct: 367 ELIRKVQAAKEEGYQKLVVLQDEKLELENRLADLEKMKVEHDVWRQSEKDQYEEKLRASQ 426
Query: 225 LHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASV--IRTEESALA 282
+ + E R ++Q+ + + EN+ LK +I L+ V + E+ L
Sbjct: 427 MAEEITRKELQSVRLKLQQQIVTIENAEKEKNENS-DLKQQISSLQIQVTSLAQSENDLL 485
Query: 283 NEKRLQEKM-----HECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQL 337
N ++ ++M EC + ++ + EA + L+ Q + L + + E +
Sbjct: 486 NSNQMLKEMVERLKQECRNFRSQAEKAQLEAEKTLEEKQIQWLEEKHKLHECITDREEKY 545
Query: 338 AASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRR 388
++ ++ A +++ K+ ++KRL E E + + L+T+ Q L R
Sbjct: 546 NQAKEKLQRAAIAQKKRKSLHENKLKRLQEKVEVLEAKKEELETENQVLNR 596
Score = 41.5 bits (93), Expect = 0.005
Identities = 60/246 (24%), Positives = 100/246 (40%), Gaps = 17/246 (6%)
Query: 146 LKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLF 205
LKA RL Q ++ + L E +EK+ + L + T L + L
Sbjct: 44 LKAEHTRL---QNEHVKLQNELKHLFNEKQTQQEKLQLLLEELRGELVEKTKDLEEMKL- 99
Query: 206 GQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSE 265
+I K + + + L+ P + R DE ++ ++L + LKSE
Sbjct: 100 -----QILTPQKLELLRAQIQQELETPMRERFRNLDE-EVEKYRAVYNKLRYEHTFLKSE 153
Query: 266 IERLKASVIRT-EESALANEK---RLQEKMHECAQLGGELDRTRDEASRALQRAHEQTET 321
E K R +E + E RL+E E +D T+D + R Q A E+
Sbjct: 154 FEHQKEEYARILDEGKIKYESEIARLEEDKEELRNQLLNVDLTKD-SKRVEQLAREKVYL 212
Query: 322 VRKC--LQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQLRILGL 379
+K L+ VAEL+ + S AQV A++ + + ++ L + A LR L
Sbjct: 213 CQKLKGLEAEVAELKAEKENSEAQVENAQRIQVRQLAEMQATVRSLEAEKQSANLRAERL 272
Query: 380 QTQVQS 385
+ ++QS
Sbjct: 273 EKELQS 278
>BC019577-1|AAH19577.1| 314|Homo sapiens Unknown (protein for
IMAGE:4937907) protein.
Length = 314
Score = 44.4 bits (100), Expect = 7e-04
Identities = 43/209 (20%), Positives = 92/209 (44%), Gaps = 10/209 (4%)
Query: 144 DLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQED 203
+L + Q+ +K ++ +++AE ++ R AR+KV + L L+ +T
Sbjct: 116 ELQEREQLLIKASKAVESLAEAGGSEIQRVKEDARKKVQQVEDLLTKRILLLEKDVTAAQ 175
Query: 204 LFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLK 263
+ + ++ + + L + L +K E GD +L+++ + E +SLK
Sbjct: 176 --AELEKAFAGTETEKALRLRLESKLSEMKKMHE--GDLAMALVLDEKDRLIEELKLSLK 231
Query: 264 SEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVR 323
S+ E L ++ E+S +A ++ +L G R+E R + A + + R
Sbjct: 232 SK-EAL-IQCLKEEKSQMA----CPDENVSSGELRGLCAAPREEKERETEAAQMEHQKER 285
Query: 324 KCLQTTVAELERQLAASRAQVSTAEKERE 352
Q + LE L +++T +K+++
Sbjct: 286 NSFQERIQALEEDLREKEREIATEKKKKK 314
>BC017659-1|AAH17659.1| 285|Homo sapiens KIAA1524 protein protein.
Length = 285
Score = 44.4 bits (100), Expect = 7e-04
Identities = 53/233 (22%), Positives = 106/233 (45%), Gaps = 21/233 (9%)
Query: 146 LKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYL--------VTTM 197
L + + RL+D + +A+A A++L + C R + R L S+ ++ +
Sbjct: 13 LASKESRLQDLLETKALALAQADRLIAQHRCQRTQAETEARTLASMLREVERKNEELSVL 72
Query: 198 TLTQEDLFGQSQSEIGR----GNKDQTV---HVLLHNS---LKPPEKPPERGGDEKQMAL 247
Q+ ++QS+I K ++V H +L S L + E+ + Q+
Sbjct: 73 LKAQQVESERAQSDIEHLFQHNRKLESVAEEHEILTKSYMELLQRNESTEKKNKDLQITC 132
Query: 248 --LNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTR 305
LN++I + + N SLK + E+ A +I EE + +L ++ H+ A L + + +
Sbjct: 133 DSLNKQIETVKKLNESLKEQNEKSIAQLIEKEEQRKEVQNQLVDREHKLANL-HQKTKVQ 191
Query: 306 DEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRL 358
+E + LQ+ E E L+ ++ E+ + S+ E ++ +L+ RL
Sbjct: 192 EEKIKTLQKEREDKEETIDILRKELSRTEQIRKELSIKASSLEVQKAQLEGRL 244
>AL451125-2|CAI14346.1| 767|Homo sapiens golgi autoantigen, golgin
subfamily a, 1 protein.
Length = 767
Score = 44.4 bits (100), Expect = 7e-04
Identities = 75/380 (19%), Positives = 154/380 (40%), Gaps = 36/380 (9%)
Query: 26 KLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQ 85
K +E K + L N+L ++ Q +N+ + R+E+DEL Q +
Sbjct: 131 KDQEWSEKMDQLEKEKNILTAQLQEMKNQSMNLF-------QRRDEMDELEGF---QQQE 180
Query: 86 LQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDL 145
L + L+ ++ + + ++ +R E++ + ++ +KL+EL
Sbjct: 181 LSKIKHMLLKKEESLGKMEQELEARTRELSRTQEEL-MNSNQMSSDLSQKLEEL------ 233
Query: 146 LKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYL-YSLYLVTTMTLTQEDL 204
+ L++ + ++ AE L +++ + + L L VT T +ED+
Sbjct: 234 -QRHYSTLEEQRDHVIASKTGAESKITALEQKEQELQALIQQLSIDLQKVTAETQEKEDV 292
Query: 205 FGQSQSEIGRGNK--DQTVHVLLHNSLKPPEKP-PERGGDEKQMALLNQRISQLAENNIS 261
Q ++ K +Q + H EK E+ ++ + LL R SQ N +
Sbjct: 293 ITHLQEKVASLEKRLEQNLSGEEHLQELLKEKTLAEQNLEDTRQQLLAARSSQAKAIN-T 351
Query: 262 LKSEIERLKASVIRTEES-------ALANEKRLQE------KMHECAQLGGELDRTRDEA 308
L++ + L+ ++ +EE A E ++QE + Q L++ E
Sbjct: 352 LETRVRELEQTLQASEEQLQQSKGIVAAQETQIQELAAANQESSHVQQQALALEQQFLER 411
Query: 309 SRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTEN 368
++AL+ E R QTT + RQL A + E E +++K+L E
Sbjct: 412 TQALEAQIVALERTRAADQTTAEQGMRQLEQENAALKECRNEYERSLQNHQFELKKLKEE 471
Query: 369 FEQAQLRILGLQTQVQSLRR 388
+ Q ++ + + ++ +R+
Sbjct: 472 WSQREIVSVAMAQALEEVRK 491
Score = 31.1 bits (67), Expect = 7.4
Identities = 27/117 (23%), Positives = 47/117 (40%), Gaps = 1/117 (0%)
Query: 49 EQAFEQ-EVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQX 107
EQ Q E ALK+C E + + +K+ ++ + + Q +EE R+Q
Sbjct: 434 EQGMRQLEQENAALKECRNEYERSLQNHQFELKKLKEEWSQREIVSVAMAQALEEVRKQR 493
Query: 108 XXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAE 164
++ I+ + Q ++ K + LQ+ I L + L Q QA E
Sbjct: 494 EEFQQQAANLTAIIDEKEQNLREKTEVLLQKEQEILQLERGHNSALLQIHQLQAELE 550
>AL354928-1|CAI39632.1| 767|Homo sapiens golgi autoantigen, golgin
subfamily a, 1 protein.
Length = 767
Score = 44.4 bits (100), Expect = 7e-04
Identities = 75/380 (19%), Positives = 154/380 (40%), Gaps = 36/380 (9%)
Query: 26 KLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQ 85
K +E K + L N+L ++ Q +N+ + R+E+DEL Q +
Sbjct: 131 KDQEWSEKMDQLEKEKNILTAQLQEMKNQSMNLF-------QRRDEMDELEGF---QQQE 180
Query: 86 LQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDL 145
L + L+ ++ + + ++ +R E++ + ++ +KL+EL
Sbjct: 181 LSKIKHMLLKKEESLGKMEQELEARTRELSRTQEEL-MNSNQMSSDLSQKLEEL------ 233
Query: 146 LKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYL-YSLYLVTTMTLTQEDL 204
+ L++ + ++ AE L +++ + + L L VT T +ED+
Sbjct: 234 -QRHYSTLEEQRDHVIASKTGAESKITALEQKEQELQALIQQLSIDLQKVTAETQEKEDV 292
Query: 205 FGQSQSEIGRGNK--DQTVHVLLHNSLKPPEKP-PERGGDEKQMALLNQRISQLAENNIS 261
Q ++ K +Q + H EK E+ ++ + LL R SQ N +
Sbjct: 293 ITHLQEKVASLEKRLEQNLSGEEHLQELLKEKTLAEQNLEDTRQQLLAARSSQAKAIN-T 351
Query: 262 LKSEIERLKASVIRTEES-------ALANEKRLQE------KMHECAQLGGELDRTRDEA 308
L++ + L+ ++ +EE A E ++QE + Q L++ E
Sbjct: 352 LETRVRELEQTLQASEEQLQQSKGIVAAQETQIQELAAANQESSHVQQQALALEQQFLER 411
Query: 309 SRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTEN 368
++AL+ E R QTT + RQL A + E E +++K+L E
Sbjct: 412 TQALEAQIVALERTRAADQTTAEQGMRQLEQENAALKECRNEYERSLQNHQFELKKLKEE 471
Query: 369 FEQAQLRILGLQTQVQSLRR 388
+ Q ++ + + ++ +R+
Sbjct: 472 WSQREIVSVAMAQALEEVRK 491
Score = 31.1 bits (67), Expect = 7.4
Identities = 27/117 (23%), Positives = 47/117 (40%), Gaps = 1/117 (0%)
Query: 49 EQAFEQ-EVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQX 107
EQ Q E ALK+C E + + +K+ ++ + + Q +EE R+Q
Sbjct: 434 EQGMRQLEQENAALKECRNEYERSLQNHQFELKKLKEEWSQREIVSVAMAQALEEVRKQR 493
Query: 108 XXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAE 164
++ I+ + Q ++ K + LQ+ I L + L Q QA E
Sbjct: 494 EEFQQQAANLTAIIDEKEQNLREKTEVLLQKEQEILQLERGHNSALLQIHQLQAELE 550
>AF312367-1|AAQ14554.1| 708|Homo sapiens La binding protein 1
protein.
Length = 708
Score = 44.4 bits (100), Expect = 7e-04
Identities = 41/188 (21%), Positives = 82/188 (43%), Gaps = 7/188 (3%)
Query: 217 KDQTVHVLLHNSLKPPEKPPERGGDEKQMAL--LNQRISQLAENNISLKSEIERLKASVI 274
K+ + + + ++ K E+ EKQ L L Q++ ++ N+ + + + ++S+
Sbjct: 419 KELELQIGMKTEMEIAMKLLEKDTHEKQDTLVALRQQLEEVKAINLQMFHKAQNAESSLQ 478
Query: 275 RTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELE 334
+ E+ + E + + M Q+ L + RA Q A E+T + + + L+
Sbjct: 479 QKNEAITSFEGKTNQVMSSMKQMEERLQHSE----RARQGAEERTTSCSRSWAVRIGALQ 534
Query: 335 RQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRRTASSTG 394
QL+ Q S+ EKE + K + + L + L + LQ QV+ L++
Sbjct: 535 LQLSQLHEQCSSLEKELKSEKEQRQALQRELQHEKNTSSLLRMELQ-QVEGLKKELRELQ 593
Query: 395 DGDGENQE 402
D E Q+
Sbjct: 594 DEKAELQK 601
>AF083037-1|AAD22767.1| 3595|Homo sapiens A-kinase anchoring protein
AKAP350 protein.
Length = 3595
Score = 44.4 bits (100), Expect = 7e-04
Identities = 74/337 (21%), Positives = 151/337 (44%), Gaps = 28/337 (8%)
Query: 53 EQEVNVR-ALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXX 111
EQ+ V + K+ +E I+EL T + E+ + + + K A +L+ E + Q
Sbjct: 1 EQDKKVENSNKEEIQEKETIIEELNTKIIEEEKKTLELKDKLTTADKLLGELQEQIVQK- 59
Query: 112 XXNTRISEQINLEIQRVKLKFQEKLQELAPIPDLLKATQMRL-KDAQQAQAIAEHNAEQL 170
N I + + LE+ K K ++ +E+ + ++ Q R KD+Q I + ++
Sbjct: 60 --NQEI-KNMKLELTNSKQKERQSSEEIKQLMGTVEELQKRNHKDSQFETDIVQRMEQET 116
Query: 171 ARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHV-LLHNSL 229
R+L R ++ +Y +V +++L Q +++ + +T H + N+L
Sbjct: 117 QRKLEQLRAELDE----MYGQQIVQM----KQELIRQHMAQM---EEMKTRHKGEMENAL 165
Query: 230 KPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQE 289
+ +E Q+ L+N I++L S+ E+LK + E A +++L++
Sbjct: 166 RSYSNITV---NEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGLILEEKCALQRQLED 222
Query: 290 KMHECAQLGGELDRTRD---EASRALQRAHEQTETVR--KCLQTTVAELERQLAAS-RAQ 343
+ E + ++ R R E L AH+ TV K + +E ++L A+
Sbjct: 223 LVEELSFSREQIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASESRKELELKHEAE 282
Query: 344 VSTAEKEREELKNRLHWQMKRLTENFEQAQLRILGLQ 380
V+ + + E L+ + + R+ E+ ++A+L L Q
Sbjct: 283 VTNYKIKLEMLEKEKNAVLDRMAES-QEAELERLRTQ 318
Score = 43.6 bits (98), Expect = 0.001
Identities = 78/382 (20%), Positives = 147/382 (38%), Gaps = 24/382 (6%)
Query: 17 RCQHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELR 76
R Q E +NKL + +M+ GLA + M +++Q V Q +E EID+L
Sbjct: 1931 RLQELEQENKLFKDDMEKLGLAIKESDAMSTQDQ----HVLFGKFAQIIQEKEVEIDQLN 1986
Query: 77 TLMKEQNDQLQ---DYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQ 133
+ + QL+ D +V + +L+ + Q + EI+++ +
Sbjct: 1987 EQVTKLQQQLKITTDNKV-IEEKNELIRDLETQIECLMSDQECVKRNREEEIEQLNEVIE 2045
Query: 134 EKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYL 193
+ QELA I + T M + +H + + E ++V + +
Sbjct: 2046 KLQQELANIG---QKTSMNAHSLSEEADSLKHQLDVVIAEKLALEQQVETANEEMTFMKN 2102
Query: 194 VTTMTLTQEDLFGQSQSEIGRGNKD-QTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRI 252
V T + + Q + R + + + + NS+ + E ++ L +
Sbjct: 2103 VLKETNFKMNQLTQELFSLKRERESVEKIQSIPENSVNVAIDHLSKDKPELEVVLTEDAL 2162
Query: 253 SQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRAL 312
L EN KS E K S+I E L E + K E Q ++ +++
Sbjct: 2163 KSL-ENQTYFKSFEENGKGSIINLETRLLQLESTVSAKDLELTQCYKQIKDMQEQGQFET 2221
Query: 313 QRAHEQTETVRKCLQTTVAEL---ERQLAASRA--------QVSTAEKEREELKNRLHWQ 361
+ ++ ++K ++ VA + QL A + Q ++E ER ++N +
Sbjct: 2222 EMLQKKIVNLQKIVEEKVAAALVSQIQLEAVQEYAKFCQDNQTISSEPERTNIQNLNQLR 2281
Query: 362 MKRLTENFEQAQLRILGLQTQV 383
L + LRI L++QV
Sbjct: 2282 EDELGSDISALTLRISELESQV 2303
Score = 35.1 bits (77), Expect = 0.46
Identities = 84/393 (21%), Positives = 160/393 (40%), Gaps = 46/393 (11%)
Query: 25 NKLRELEMKFEGLATHTNMLMGSKE--QAFEQEVNVRALKQCYREAREEIDELRTLMKEQ 82
N+L+ELE + + + +L KE +A V + L++ + +E++ E++ ++
Sbjct: 1645 NRLQELEAEQQQIQEERELLSRQKEAMKAEAGPVEQQLLQETEKLMKEKL-EVQCQAEKD 1703
Query: 83 NDQLQDYRVKYLQAQQLVEEQ-RRQXXXXXXXNTRISE--QINLEIQRVKLKFQEKLQEL 139
D LQ +VK L+ VEEQ R NT + + Q N +++ K ++ L E
Sbjct: 1704 RDDLQK-QVKALEID--VEEQVSRFIELEQEKNTELMDLRQQNQALEKQLEKMRKFLDEQ 1760
Query: 140 A--------PIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSL 191
A ++ + +LK + Q I+EH ++ + N +EK
Sbjct: 1761 AIDREHERDVFQQEIQKLEQQLKVVPRFQPISEHQTREVEQLANHLKEKTDK-------- 1812
Query: 192 YLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQR 251
+ + L++E L Q K + L +L ++ D K + +
Sbjct: 1813 --CSELLLSKEQLQRDIQERNEEIEKLEFRVRELEQALLVSADTFQKVEDRKHFGAVEAK 1870
Query: 252 ISQLAENNISLKSE-IERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASR 310
E + + + I+R + + EE + L+ K E QL +L+ + E++
Sbjct: 1871 PELSLEVQLQAERDAIDRKEKEITNLEEQLEQFREELENKNEEVQQLHMQLEIQKKESTT 1930
Query: 311 ALQRAHEQTETVRKCLQTTVAELERQLAASR----------AQVSTAEKERE-----ELK 355
LQ ++ + + ++ ++ A S AQ+ EKE E E
Sbjct: 1931 RLQELEQENKLFKDDMEKLGLAIKESDAMSTQDQHVLFGKFAQI-IQEKEVEIDQLNEQV 1989
Query: 356 NRLHWQMKRLTEN--FEQAQLRILGLQTQVQSL 386
+L Q+K T+N E+ I L+TQ++ L
Sbjct: 1990 TKLQQQLKITTDNKVIEEKNELIRDLETQIECL 2022
>AC012487-1|AAX88838.1| 1583|Homo sapiens unknown protein.
Length = 1583
Score = 44.4 bits (100), Expect = 7e-04
Identities = 60/304 (19%), Positives = 128/304 (42%), Gaps = 37/304 (12%)
Query: 92 KYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIP-DLLKATQ 150
K L+A++L +EQ+ + E++ +++Q+ K + Q+ +QEL + D + T
Sbjct: 1000 KELEAEKLQKEQKIKEHATTVNEL---EELQVQLQKQKKQLQKTMQELELVKKDAQQTTL 1056
Query: 151 MRLKDAQQAQAIAEHNA---------EQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQ 201
M ++ A + + E N E L +E+ ++K + + SL +
Sbjct: 1057 MNMEIADYERLMKELNQKLTNKNNKIEDLEQEIKIQKQKQETLQEEITSLQSSVQQYEEK 1116
Query: 202 ----EDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAE 257
+ L +++ E+ + +T H++L SLK E ++Q+ + +++++
Sbjct: 1117 NTKIKQLLVKTKKELADSKQAETDHLILQASLKG-----ELEASQQQVEVYKIQLAEITS 1171
Query: 258 NNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHE 317
+ E LK S + + + A ++R+ EC E E R H
Sbjct: 1172 EKHKIH---EHLKTSAEQHQRTLSAYQQRVTALQEECRAAKAEQATVTSEFESYKVRVHN 1228
Query: 318 QTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQLRIL 377
V + ++ + S+A+ A++ERE L+ + +L ++ Q+ +
Sbjct: 1229 ------------VLKQQKNKSMSQAETEGAKQEREHLEMLIDQLKIKLQDSQNNLQINVS 1276
Query: 378 GLQT 381
LQT
Sbjct: 1277 ELQT 1280
Score = 30.7 bits (66), Expect = 9.8
Identities = 30/142 (21%), Positives = 62/142 (43%), Gaps = 8/142 (5%)
Query: 242 EKQMALLNQRISQLAENNISLKSEIE--RLKASVIRTEESALANEK-RLQEKMHECAQLG 298
EK+ ++I+++ + K E++ R + ++ E +L +EK +L M + Q
Sbjct: 856 EKECKEKEEKINKIKLVAVKAKKELDSSRKETQTVKEELESLRSEKDQLSASMRDLIQGA 915
Query: 299 GELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRL 358
E + ++ + E + + +L RQL S Q T + E+L R+
Sbjct: 916 ESYKNLLLEYEKQSEQLDVEKERANN-FEHRIEDLTRQLRNSTLQCETINSDNEDLLARI 974
Query: 359 HWQMKRLTENFEQAQLRILGLQ 380
+ L N + +++IL +Q
Sbjct: 975 ----ETLQSNAKLLEVQILEVQ 992
>AB208858-1|BAD92095.1| 400|Homo sapiens golgin 97 variant protein.
Length = 400
Score = 44.4 bits (100), Expect = 7e-04
Identities = 75/380 (19%), Positives = 154/380 (40%), Gaps = 36/380 (9%)
Query: 26 KLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQ 85
K +E K + L N+L ++ Q +N+ + R+E+DEL Q +
Sbjct: 30 KDQEWSEKMDQLEKEKNILTAQLQEMKNQSMNLF-------QRRDEMDELEGF---QQQE 79
Query: 86 LQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDL 145
L + L+ ++ + + ++ +R E++ + ++ +KL+EL
Sbjct: 80 LSKIKHMLLKKEESLGKMEQELEARTRELSRTQEEL-MNSNQMSSDLSQKLEEL------ 132
Query: 146 LKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYL-YSLYLVTTMTLTQEDL 204
+ L++ + ++ AE L +++ + + L L VT T +ED+
Sbjct: 133 -QRHYSTLEEQRDHVIASKTGAESKITALEQKEQELQALIQQLSIDLQKVTAETQEKEDV 191
Query: 205 FGQSQSEIGRGNK--DQTVHVLLHNSLKPPEKP-PERGGDEKQMALLNQRISQLAENNIS 261
Q ++ K +Q + H EK E+ ++ + LL R SQ N +
Sbjct: 192 ITHLQEKVASLEKRLEQNLSGEEHVQELLKEKTLAEQNLEDTRQQLLAARSSQAKAIN-T 250
Query: 262 LKSEIERLKASVIRTEES-------ALANEKRLQE------KMHECAQLGGELDRTRDEA 308
L++ + L+ ++ +EE A E ++QE + Q L++ E
Sbjct: 251 LETRVRELEQTLQASEEQLQQSKGIVAAQETQIQELAAANQESSHVQQQALALEQQFLER 310
Query: 309 SRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTEN 368
++AL+ E R QTT + RQL A + E E +++K+L E
Sbjct: 311 TQALEAQIVALERTRAADQTTAEQGMRQLEQENAALKECRNEYERSLQNHQFELKKLKEE 370
Query: 369 FEQAQLRILGLQTQVQSLRR 388
+ Q ++ + + ++ +R+
Sbjct: 371 WSQREIVSVAMAQALEEVRK 390
>AB002334-1|BAA20794.2| 1635|Homo sapiens KIAA0336 protein.
Length = 1635
Score = 44.4 bits (100), Expect = 7e-04
Identities = 60/304 (19%), Positives = 128/304 (42%), Gaps = 37/304 (12%)
Query: 92 KYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIP-DLLKATQ 150
K L+A++L +EQ+ + E++ +++Q+ K + Q+ +QEL + D + T
Sbjct: 1052 KELEAEKLQKEQKIKEHATTVNEL---EELQVQLQKEKKQLQKTMQELELVKKDAQQTTL 1108
Query: 151 MRLKDAQQAQAIAEHNA---------EQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQ 201
M ++ A + + E N E L +E+ ++K + + SL +
Sbjct: 1109 MNMEIADYERLMKELNQKLTNKNNKIEDLEQEIKIQKQKQETLQEEITSLQSSVQQYEEK 1168
Query: 202 ----EDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAE 257
+ L +++ E+ + +T H++L SLK E ++Q+ + +++++
Sbjct: 1169 NTKIKQLLVKTKKELADSKQAETDHLILQASLKG-----ELEASQQQVEVYKIQLAEITS 1223
Query: 258 NNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHE 317
+ E LK S + + + A ++R+ EC E E R H
Sbjct: 1224 EKHKIH---EHLKTSAEQHQRTLSAYQQRVTALQEECRAAKAEQATVTSEFESYKVRVHN 1280
Query: 318 QTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQLRIL 377
V + ++ + S+A+ A++ERE L+ + +L ++ Q+ +
Sbjct: 1281 ------------VLKQQKNKSMSQAETEGAKQEREHLEMLIDQLKIKLQDSQNNLQINVS 1328
Query: 378 GLQT 381
LQT
Sbjct: 1329 ELQT 1332
Score = 30.7 bits (66), Expect = 9.8
Identities = 30/142 (21%), Positives = 62/142 (43%), Gaps = 8/142 (5%)
Query: 242 EKQMALLNQRISQLAENNISLKSEIE--RLKASVIRTEESALANEK-RLQEKMHECAQLG 298
EK+ ++I+++ + K E++ R + ++ E +L +EK +L M + Q
Sbjct: 908 EKECKEKEEKINKIKLVAVKAKKELDSSRKETQTVKEELESLRSEKDQLSASMRDLIQGA 967
Query: 299 GELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRL 358
E + ++ + E + + +L RQL S Q T + E+L R+
Sbjct: 968 ESYKNLLLEYEKQSEQLDVEKERANN-FEHRIEDLTRQLRNSTLQCETINSDNEDLLARI 1026
Query: 359 HWQMKRLTENFEQAQLRILGLQ 380
+ L N + +++IL +Q
Sbjct: 1027 ----ETLQSNAKLLEVQILEVQ 1044
>BC117132-1|AAI17133.1| 1306|Homo sapiens kinectin 1 (kinesin
receptor) protein.
Length = 1306
Score = 44.0 bits (99), Expect = 0.001
Identities = 72/363 (19%), Positives = 143/363 (39%), Gaps = 25/363 (6%)
Query: 24 QNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQN 83
+N+++ L K L Q E E ++ + ++I E +K Q
Sbjct: 526 ENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQI 585
Query: 84 DQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIP 143
Q A L EE + + + + E R+ K +E+L+++ +
Sbjct: 586 QQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSK-EEELKDIQNMN 644
Query: 144 DLLKATQMRLKDAQQAQAIAEHNAEQLAR-------ELNCAREKVVH-IFRYLYSLYLVT 195
LLKA +L+ QA A H E++ + ++ E++ H I + ++
Sbjct: 645 FLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILN 704
Query: 196 TMTLTQEDLFGQSQSEIG-RGNKD--QTVHVLLH---NSLKPPEKPPERGGDEKQMALLN 249
+ + Q+ + + NKD + + + LK E+ E G Q+A
Sbjct: 705 DQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETG--LIQVATKE 762
Query: 250 QRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEAS 309
+ ++ + N SL E++ LKA + S + + L++ +HE G++ +
Sbjct: 763 EELNAIRTENSSLTKEVQDLKAKQ-NDQVSFASLVEELKKVIHE---KDGKIKSVEELLE 818
Query: 310 RALQRAHEQTETVRKCLQTTVAELERQLAASRAQVST----AEKEREELKNRLHWQMKRL 365
L + + +TV+ + + V EL+ L Q++T E++ ++L N W
Sbjct: 819 AELLKVANKEKTVQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQ 878
Query: 366 TEN 368
EN
Sbjct: 879 EEN 881
Score = 42.7 bits (96), Expect = 0.002
Identities = 76/362 (20%), Positives = 150/362 (41%), Gaps = 32/362 (8%)
Query: 73 DELRTLMKEQNDQLQDYRVKYLQAQQLV-------EEQRRQXXXXXXXNTRISEQINLEI 125
D + TL KE N V Y + QQ+ E+ + N + + ++
Sbjct: 378 DRIGTLEKEHNVFQNKIHVSYQETQQMQMKFQQVREQMEAEIAHLKQENGILRDAVSNTT 437
Query: 126 QRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIF 185
+++ K +L +L L Q + + + NAEQ A +L ++ +
Sbjct: 438 NQLESKQSAELNKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQAATQLKVQLQEAERRW 497
Query: 186 RYLYSLYLVTTM--TLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPER----- 238
+ S T Q+DL QS+ + + N+ Q++H L ++L ++ +R
Sbjct: 498 EEVQSYIRKRTAEHEAAQQDL--QSKF-VAKENEVQSLHSKLTDTLVSKQQLEQRLMQLM 554
Query: 239 GGDEKQM---ALLNQRISQLAENNISLKSEIERLKASV-IRTEESALANE--KRLQEKMH 292
++K++ L ++ + E N +LK++I++ + + +T S LA E K + EK
Sbjct: 555 ESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLAEELHKVIAEKDK 614
Query: 293 ECAQ----LGGELDR--TRDEASRALQRAHEQTET-VRK--CLQTTVAELERQLAASRAQ 343
+ Q L E DR +++E + +Q + + V+K L A +L +
Sbjct: 615 QIKQTEDSLASERDRLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQS 674
Query: 344 VSTAEKEREELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRRTASSTGDGDGENQEC 403
V + + L+ +L ++ E F+ + L+++VQ L+ S + D Q
Sbjct: 675 VYVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNKDVVEQME 734
Query: 404 TC 405
C
Sbjct: 735 KC 736
Score = 31.5 bits (68), Expect = 5.6
Identities = 36/182 (19%), Positives = 73/182 (40%), Gaps = 8/182 (4%)
Query: 225 LHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTE------- 277
LH K ++ +++ +L ++ + E + L+ E E+ K+ + TE
Sbjct: 1072 LHGFEKKAKECMAGTSGSEEVKVLEHKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQ 1131
Query: 278 ESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQL 337
S E + + K+ E + ++ + + + L+R + + + L+ LE +L
Sbjct: 1132 RSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELERLRSENKDIEN-LRREREHLEMEL 1190
Query: 338 AASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRRTASSTGDGD 397
+ + ST E ELK +L+ + +L + Q L QSL S
Sbjct: 1191 EKAEMERSTYVTEVRELKAQLNETLTKLRTEQNERQKVAGDLHKAQQSLELIQSKIVKAA 1250
Query: 398 GE 399
G+
Sbjct: 1251 GD 1252
>BC112337-1|AAI12338.1| 1306|Homo sapiens kinectin 1 (kinesin
receptor) protein.
Length = 1306
Score = 44.0 bits (99), Expect = 0.001
Identities = 72/363 (19%), Positives = 143/363 (39%), Gaps = 25/363 (6%)
Query: 24 QNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQN 83
+N+++ L K L Q E E ++ + ++I E +K Q
Sbjct: 526 ENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQI 585
Query: 84 DQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIP 143
Q A L EE + + + + E R+ K +E+L+++ +
Sbjct: 586 QQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSK-EEELKDIQNMN 644
Query: 144 DLLKATQMRLKDAQQAQAIAEHNAEQLAR-------ELNCAREKVVH-IFRYLYSLYLVT 195
LLKA +L+ QA A H E++ + ++ E++ H I + ++
Sbjct: 645 FLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILN 704
Query: 196 TMTLTQEDLFGQSQSEIG-RGNKD--QTVHVLLH---NSLKPPEKPPERGGDEKQMALLN 249
+ + Q+ + + NKD + + + LK E+ E G Q+A
Sbjct: 705 DQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETG--LIQVATKE 762
Query: 250 QRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEAS 309
+ ++ + N SL E++ LKA + S + + L++ +HE G++ +
Sbjct: 763 EELNAIRTENSSLTKEVQDLKAKQ-NDQVSFASLVEELKKVIHE---KDGKIKSVEELLE 818
Query: 310 RALQRAHEQTETVRKCLQTTVAELERQLAASRAQVST----AEKEREELKNRLHWQMKRL 365
L + + +TV+ + + V EL+ L Q++T E++ ++L N W
Sbjct: 819 AELLKVANKEKTVQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQ 878
Query: 366 TEN 368
EN
Sbjct: 879 EEN 881
Score = 42.7 bits (96), Expect = 0.002
Identities = 76/362 (20%), Positives = 150/362 (41%), Gaps = 32/362 (8%)
Query: 73 DELRTLMKEQNDQLQDYRVKYLQAQQLV-------EEQRRQXXXXXXXNTRISEQINLEI 125
D + TL KE N V Y + QQ+ E+ + N + + ++
Sbjct: 378 DRIGTLEKEHNVFQNKIHVSYQETQQMQMKFQQVREQMEAEIAHLKQENGILRDAVSNTT 437
Query: 126 QRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIF 185
+++ K +L +L L Q + + + NAEQ A +L ++ +
Sbjct: 438 NQLESKQSAELNKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQAATQLKVQLQEAERRW 497
Query: 186 RYLYSLYLVTTM--TLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPER----- 238
+ S T Q+DL QS+ + + N+ Q++H L ++L ++ +R
Sbjct: 498 EEVQSYIRKRTAEHEAAQQDL--QSKF-VAKENEVQSLHSKLTDTLVSKQQLEQRLMQLM 554
Query: 239 GGDEKQM---ALLNQRISQLAENNISLKSEIERLKASV-IRTEESALANE--KRLQEKMH 292
++K++ L ++ + E N +LK++I++ + + +T S LA E K + EK
Sbjct: 555 ESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLAEELHKVIAEKDK 614
Query: 293 ECAQ----LGGELDR--TRDEASRALQRAHEQTET-VRK--CLQTTVAELERQLAASRAQ 343
+ Q L E DR +++E + +Q + + V+K L A +L +
Sbjct: 615 QIKQTEDSLASERDRLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQS 674
Query: 344 VSTAEKEREELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRRTASSTGDGDGENQEC 403
V + + L+ +L ++ E F+ + L+++VQ L+ S + D Q
Sbjct: 675 VYVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNKDVVEQME 734
Query: 404 TC 405
C
Sbjct: 735 KC 736
Score = 31.5 bits (68), Expect = 5.6
Identities = 36/182 (19%), Positives = 73/182 (40%), Gaps = 8/182 (4%)
Query: 225 LHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTE------- 277
LH K ++ +++ +L ++ + E + L+ E E+ K+ + TE
Sbjct: 1072 LHGFEKKAKECMAGTSGSEEVKVLEHKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQ 1131
Query: 278 ESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQL 337
S E + + K+ E + ++ + + + L+R + + + L+ LE +L
Sbjct: 1132 RSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELERLRSENKDIEN-LRREREHLEMEL 1190
Query: 338 AASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRRTASSTGDGD 397
+ + ST E ELK +L+ + +L + Q L QSL S
Sbjct: 1191 EKAEMERSTYVTEVRELKAQLNETLTKLRTEQNERQKVAGDLHKAQQSLELIQSKIVKAA 1250
Query: 398 GE 399
G+
Sbjct: 1251 GD 1252
>BC014109-1|AAH14109.1| 670|Homo sapiens leucine rich repeat
containing 45 protein.
Length = 670
Score = 44.0 bits (99), Expect = 0.001
Identities = 63/299 (21%), Positives = 125/299 (41%), Gaps = 24/299 (8%)
Query: 66 REAREEIDELRTLMKEQNDQLQDYRVKY--LQAQQLVEEQRRQXXXXXXXNTRISEQINL 123
R + + +L+ + E++ + + K +A + EQ+ Q T EQ++L
Sbjct: 278 RASAARVGQLQEALNERHSIINALKAKLQMTEAALALSEQKAQDLGELLA-TAEQEQLSL 336
Query: 124 EIQRVK-LKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVV 182
++ K LK ++ QE A L L A + + ++ ++L R+ C +E++
Sbjct: 337 SQRQAKELKLEQ--QEAAERESKLLRD---LSAANEKNLLLQNQVDELERKFRCQQEQLF 391
Query: 183 HIFRYLYSLYLVTTMTLTQ-EDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGD 241
+ + S+ M Q E+ + + +D SL+ E
Sbjct: 392 QTRQEMTSMSAELKMRAIQAEERLDMEKRRCRQSLEDS-------ESLRIKEVEHMTRHL 444
Query: 242 EKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGEL 301
E+ + +R+ +L +SL+ E+ R+KA+ + E A E+ ++ K + L
Sbjct: 445 EESEKAMQERVQRLEAARLSLEEELSRVKAAAL--SERGQAEEELIKAKSQARLEEQQRL 502
Query: 302 DRTRDEASRALQRAHEQTETVRKCLQT--TVAELERQLAASRAQVSTAEKEREELKNRL 358
D+ R L +A ++ + CLQ VAE + +++ QV + EEL+ L
Sbjct: 503 AHLEDKL-RLLAQARDEAQGA--CLQQKQVVAEAQTRVSQLGLQVEGLRRRLEELQQEL 558
>AL137068-6|CAI12359.1| 346|Homo sapiens centrosomal protein 110kDa
protein.
Length = 346
Score = 44.0 bits (99), Expect = 0.001
Identities = 68/321 (21%), Positives = 132/321 (41%), Gaps = 20/321 (6%)
Query: 47 SKEQAFEQEVNVRALKQCYREAREEIDEL-RTLMKEQNDQ-LQDYRVKYLQAQQLVEEQR 104
S+++ E N+ L Q + E++EL RT+ K Q + D V+ L + +E+
Sbjct: 21 SEKEMEELHHNIDDLLQEKKSLECEVEELHRTVQKRQQQKDFIDGNVESLMTELEIEKSL 80
Query: 105 RQXXXXXXXNTRISEQI---NLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQA 161
+ I + + E++ E EL+ + K + DA+++
Sbjct: 81 KHHEDIVDEIECIEKTLLKRRSELREADRLLAEAESELSCTKEKTKNAVEKFTDAKRSLL 140
Query: 162 IAEHNAEQLARELNCAREKVVHIFRYLYSLYL----VTTMTLTQEDLFGQSQSEIGRGNK 217
E +AE+L R +V + L SL + + QE++ + + K
Sbjct: 141 QTESDAEELERRAQETAVNLVKADQQLRSLQADAKDLEQHKIKQEEILKEINKIVAA--K 198
Query: 218 DQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQ--RISQLAENNISL---KSEIERLKAS 272
D L K E+ + D +MA N+ + L E+ + L ++E+E+LK+
Sbjct: 199 DSDFQCLSKKKEKLTEELQKLQKDI-EMAERNEDHHLQVLKESEVLLQAKRAELEKLKSQ 257
Query: 273 VIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQ-TTVA 331
V ++ +++L K E L G + + + + AL+ +TE KC V
Sbjct: 258 VTSQQQEMAVLDRQLGHKKEELHLLQGSMVQAKADLQEALRLG--ETEVTEKCNHIREVK 315
Query: 332 ELERQLAASRAQVSTAEKERE 352
L +L+ + +++ ER+
Sbjct: 316 SLLEELSFQKGELNVQISERK 336
>Y12490-1|CAA73095.1| 1979|Homo sapiens Golgi-associated
microtubule-binding protein protein.
Length = 1979
Score = 43.6 bits (98), Expect = 0.001
Identities = 66/340 (19%), Positives = 140/340 (41%), Gaps = 25/340 (7%)
Query: 29 ELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQD 88
+L+M+ E L ++L KE E ++++ L Y E I T + +L D
Sbjct: 419 KLKMRIEVLEKEKSLLSQEKE---ELQMSLLKLNNEY----EVIKSTATRDISLDSELHD 471
Query: 89 YRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPD-LLK 147
R+ +Q + + + + Q N E + + +++L + D ++
Sbjct: 472 LRLNLEAKEQELNQSISEKETLIAEIEELDRQ-NQEATKHMILIKDQLSKQQNEGDSIIS 530
Query: 148 ATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQ 207
+ L D ++ E + + +EL+ +EK++ S + + LT++ L +
Sbjct: 531 KLKQDLNDEKKRVHQLEDDKMDITKELDVQKEKLIQ------SEVALNDLHLTKQKLEDK 584
Query: 208 SQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIE 267
++ + + NK Q +V + K R +E+ + N+ + L +++ S
Sbjct: 585 VENLVDQLNKSQESNVSIQKE-NLELKEHIRQNEEELSRIRNELMQSLNQDSNS------ 637
Query: 268 RLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQ 327
K ++++ E+ + N L++ + E QL L + + ++ E VR L+
Sbjct: 638 NFKDTLLKEREAEVRN---LKQNLSELEQLNENLKKVAFDVKMENEKLVLACEDVRHQLE 694
Query: 328 TTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLTE 367
+A + V T + E+ E++ L W KRL E
Sbjct: 695 ECLAGNNQLSLEKNTIVETLKMEKGEIEAELCWAKKRLLE 734
Score = 40.3 bits (90), Expect = 0.012
Identities = 82/400 (20%), Positives = 170/400 (42%), Gaps = 39/400 (9%)
Query: 19 QHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTL 78
+ E Q L +L ++E + + + + + +N+ A +Q E + I E TL
Sbjct: 437 EKEELQMSLLKLNNEYEVIKSTATRDISLDSELHDLRLNLEAKEQ---ELNQSISEKETL 493
Query: 79 MKEQNDQLQDYRVKYLQAQQLVEEQ-RRQXXXXXXXNTRISEQINLEIQRVKLKFQEKL- 136
+ E ++L + + L+++Q +Q +++ + +N E +RV +K+
Sbjct: 494 IAEI-EELDRQNQEATKHMILIKDQLSKQQNEGDSIISKLKQDLNDEKKRVHQLEDDKMD 552
Query: 137 --QELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVV-----------H 183
+EL + L +++ L D + E E L +LN ++E V H
Sbjct: 553 ITKELDVQKEKLIQSEVALNDLHLTKQKLEDKVENLVDQLNKSQESNVSIQKENLELKEH 612
Query: 184 IFRYLYSLYLVTT---MTLTQED-------LFGQSQSEIGRGNKDQTVHVLLHNSLKPPE 233
I + L + +L Q+ L + ++E+ ++ + L+ +LK
Sbjct: 613 IRQNEEELSRIRNELMQSLNQDSNSNFKDTLLKEREAEVRNLKQNLSELEQLNENLKKVA 672
Query: 234 KPPERGGDEKQMA---LLNQRISQLAENN-ISLKSE--IERLKASVIRTEESALANEKRL 287
+ ++ +A + +Q LA NN +SL+ +E LK E +KRL
Sbjct: 673 FDVKMENEKLVLACEDVRHQLEECLAGNNQLSLEKNTIVETLKMEKGEIEAELCWAKKRL 732
Query: 288 QEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTA 347
E+ ++ + EL R+ + ALQ HE + + +AEL++ + Q+ T
Sbjct: 733 LEEANKYEKTIEELSNARNLNTSALQLEHEHLIKLNQKKDMEIAELKKNI----EQMDTD 788
Query: 348 EKEREELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLR 387
KE +++ + + K+LT+ + ++ I L+ + L+
Sbjct: 789 HKETKDVLSSSLEEQKQLTQLINKKEIFIEKLKERSSKLQ 828
Score = 35.9 bits (79), Expect = 0.26
Identities = 26/145 (17%), Positives = 66/145 (45%), Gaps = 3/145 (2%)
Query: 242 EKQM--ALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGG 299
+KQM L + +L + E+ERL+ ++ +E+S +++ + +
Sbjct: 1555 QKQMENTALQNEVQRLRDKEFRSNQELERLRNHLLESEDSYTREALAAEDREAKLRKKVT 1614
Query: 300 ELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLH 359
L+ +S A++ A Q + LQ + + +Q + Q+S ++++ ++ L
Sbjct: 1615 VLEEKLVSSSNAMENASHQASVQVESLQEQLNVVSKQRDETALQLSVSQEQVKQYALSLA 1674
Query: 360 WQMKRLTENFEQAQLRILGLQTQVQ 384
++ + E+F+Q + + + + Q
Sbjct: 1675 -NLQMVLEHFQQEEKAMYSAELEKQ 1698
Score = 34.3 bits (75), Expect = 0.80
Identities = 77/379 (20%), Positives = 146/379 (38%), Gaps = 34/379 (8%)
Query: 22 ETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMKE 81
E Q +L +L K E ++ ++ + R+ EE D MKE
Sbjct: 801 EEQKQLTQLINKKEIFIEKLKERSSKLQEELDKYSQALRKNEILRQTIEEKDRSLGSMKE 860
Query: 82 QNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAP 141
+N+ LQ+ + ++L EEQ R ++ E+ ++ +E L+E
Sbjct: 861 ENNHLQE------ELERLREEQSRTAPVADPKTLDSVTELASEVSQLN-TIKEHLEE--- 910
Query: 142 IPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQ 201
+K Q ++D Q++ QL + L ++K + FRY + M T
Sbjct: 911 ---EIKHHQKIIEDQNQSKM-------QLLQSLQ-EQKKEMDEFRYQHE-----QMNATH 954
Query: 202 EDLFGQSQSEIGRGNKD-QTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNI 260
LF + EI K + + LH + + E ++ LN I +E +
Sbjct: 955 TQLFLEKDEEIKSLQKTIEQIKTQLHEERQDIQTDNSDIFQETKVQSLN--IENGSEKHD 1012
Query: 261 SLKSEIERLKASVIRTE-ESALANEKR--LQEKMHECAQ-LGGELDRTRDEASRALQRAH 316
K+E ERL + E E L NEK L +++ + ++ G+L + + +Q H
Sbjct: 1013 LSKAETERLVKGIKERELEIKLLNEKNISLTKQIDQLSKDEVGKLTQIIQQKDLEIQALH 1072
Query: 317 EQTETVRKCLQTTVAELERQ-LAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQLR 375
+ + + + Q A R +V E+ + L + ++ + +
Sbjct: 1073 ARISSTSHTQDVVYLQQQLQAYAMEREKVFAVLNEKTRENSHLKTEYHKMMDIVAAKEAA 1132
Query: 376 ILGLQTQVQSLRRTASSTG 394
++ LQ + + L S+G
Sbjct: 1133 LIKLQDENKKLSTRFESSG 1151
>X03541-1|CAA27243.1| 641|Homo sapiens protein ( Human mRNA of trk
oncogene. ).
Length = 641
Score = 43.6 bits (98), Expect = 0.001
Identities = 40/150 (26%), Positives = 73/150 (48%), Gaps = 10/150 (6%)
Query: 249 NQRISQLAENNISLKSEIERLKASVIRTEESA-LANE--KRLQEKMHECAQLGGELDRTR 305
++R ++ EN +LK E E+++ I+ EE+ +A E ++ +E + + G+L+RT
Sbjct: 87 SERGMKVIENR-ALKDE-EKMELQEIQLEEAKHIAEEADRKYEEVARKLVIIEGDLERTE 144
Query: 306 DEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRL 365
+ A A R E E +R Q + L+A+ + S E + EE L ++K
Sbjct: 145 ERAELAESRCREMDEQIRLMDQNL-----KCLSAAEEKYSQKEDKYEEEIKILTDKLKEA 199
Query: 366 TENFEQAQLRILGLQTQVQSLRRTASSTGD 395
E A+ + L+ + L T S++GD
Sbjct: 200 ETRAEFAERSVAKLEKTIDDLEDTNSTSGD 229
>U52962-1|AAD10838.1| 3321|Homo sapiens kendrin protein.
Length = 3321
Score = 43.6 bits (98), Expect = 0.001
Identities = 45/141 (31%), Positives = 66/141 (46%), Gaps = 18/141 (12%)
Query: 252 ISQLAENNISLK------SEIERLKASVIRTEESALANEKRLQ-EKMHECAQLGGELDRT 304
+ +L E N SLK SEIE LKA++ +E N+KRLQ EK E QL +++
Sbjct: 1683 LRELEEENTSLKVIYTRSSEIEELKATIENLQE----NQKRLQKEKAEEIEQLHEVIEKL 1738
Query: 305 RDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKE-----REELKNRLH 359
+ E S HE +++ LQ+ + L Q R Q E E +E L L
Sbjct: 1739 QHELSLMGPVVHEVSDSQAGSLQSEL--LCSQAGGPRGQALQGELEAALEAKEALSRLLA 1796
Query: 360 WQMKRLTENFEQAQLRILGLQ 380
Q +R ++ E Q R+ G +
Sbjct: 1797 DQERRHSQALEALQQRLQGAE 1817
Score = 36.7 bits (81), Expect = 0.15
Identities = 30/115 (26%), Positives = 58/115 (50%), Gaps = 3/115 (2%)
Query: 246 ALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTR 305
++L+ + ++L L+SE + +A + EE L + +R + +L L+ R
Sbjct: 2628 SMLSSKENELKAALQELESEQGKGRALQSQLEEEQLRHLQRESQSAKALEELRASLETQR 2687
Query: 306 DEASR-ALQRAHEQT--ETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNR 357
++SR + HEQT + ++K L+ + E LA R+Q+S +K+ K+R
Sbjct: 2688 AQSSRLCVALKHEQTAKDNLQKELRIEHSRCEALLAQERSQLSELQKDLAAEKSR 2742
Score = 32.3 bits (70), Expect = 3.2
Identities = 29/133 (21%), Positives = 59/133 (44%), Gaps = 13/133 (9%)
Query: 249 NQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQ--------LGGE 300
N+ + + ++ LK ++E++K ++I + L N K+ E M + Q + E
Sbjct: 699 NRNLFEKLQHETRLKDDLEKVKHNLIEDHQKELNNAKQKTELMKQEFQRKETDWKVMKEE 758
Query: 301 LDRTRDEASRAL-----QRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELK 355
L R +E + ++A + +T+ L+ AE+ + AQ+ E+ E +
Sbjct: 759 LQREAEEKLTLMLLELREKAESEKQTIINKLELREAEMRQLQDQQAAQILDLERSLTEQQ 818
Query: 356 NRLHWQMKRLTEN 368
RL + LT +
Sbjct: 819 ARLQQLEQDLTSD 831
>BC128578-1|AAI28579.1| 751|Homo sapiens RRBP1 protein protein.
Length = 751
Score = 43.6 bits (98), Expect = 0.001
Identities = 87/410 (21%), Positives = 159/410 (38%), Gaps = 39/410 (9%)
Query: 17 RCQHRETQNKLRELEMKFEGLATHTNM----LMGSKEQAFEQEVNVRALKQCYREAREEI 72
+ HRE++ L++ + HT L E+A EQ+ + L + + E+
Sbjct: 211 QASHRESEEALQKRLDEVSRELCHTQSSHASLRADAEKAQEQQQQMAELHSKLQSSEAEV 270
Query: 73 DELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKF 132
+ + QLQ+ R + QL E R R ++ + Q +
Sbjct: 271 RSKCEELSGLHGQLQEARA---ENSQLTERIRSIEALLEAGQARDAQDVQAS-QAEADQQ 326
Query: 133 QEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNA--------EQLARELNCAREKVVHI 184
Q +L+EL L+ + L++A + Q + ++ E LA +EK+ +
Sbjct: 327 QTRLKELESQVSGLEKEAIELREAVEQQKVKNNDLREKNWKAMEALATAEQACKEKLHSL 386
Query: 185 FRYLYS----LYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNS---LKPPEKPPE 237
+ L L+ T+ S + + N + + L LK P P E
Sbjct: 387 TQAKEESEKQLCLIEAQTMEALLALLPELSVLAQQNYTEWLQDLKEKGPTLLKHPPAPAE 446
Query: 238 RGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHEC-AQ 296
D L ++ + E +L++E ++ ++ + TE +K ++E+ A+
Sbjct: 447 PSSD------LASKLREAEETQSTLQAECDQYRSILAETEGMLRDLQKSVEEEEQVWRAK 500
Query: 297 LGG---ELDRTR------DEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTA 347
+G EL ++R +E L+ E ++ VR+ AELE+ +AA+ A+
Sbjct: 501 VGAAEEELQKSRVTVKHLEEIVEKLKGELESSDQVREHTSHLEAELEKHMAAASAECQNY 560
Query: 348 EKEREELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRRTASSTGDGD 397
KE L+ L +L +AQ + L Q L S DGD
Sbjct: 561 AKEVAGLRQLLLESQSQLDAAKSEAQKQSDELALVRQQLSEMKSHVEDGD 610
Score = 42.3 bits (95), Expect = 0.003
Identities = 80/398 (20%), Positives = 150/398 (37%), Gaps = 38/398 (9%)
Query: 17 RCQHRETQNKLRELEMKFE-GLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDEL 75
R ++ + ++R +E E G A + S+ +A +Q+ ++ L+ +E EL
Sbjct: 288 RAENSQLTERIRSIEALLEAGQARDAQDVQASQAEADQQQTRLKELESQVSGLEKEAIEL 347
Query: 76 RTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEK 135
R +++Q + D R K +A + + + T+ E+ ++ ++ + E
Sbjct: 348 REAVEQQKVKNNDLREKNWKAMEALATAEQACKEKLHSLTQAKEESEKQLCLIEAQTMEA 407
Query: 136 LQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVT 195
L LA +P+L Q + Q + L + E + L
Sbjct: 408 L--LALLPELSVLAQQNYTEWLQD---LKEKGPTLLKHPPAPAEPSSDLASKLREAEETQ 462
Query: 196 TMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKP--PERGGDEKQMALLNQRIS 253
+ + D + +E +D L S++ E+ + G E+++ +
Sbjct: 463 STLQAECDQYRSILAETEGMLRD------LQKSVEEEEQVWRAKVGAAEEELQKSRVTVK 516
Query: 254 QLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTR-------- 305
L E LK E+E T EK + EC E+ R
Sbjct: 517 HLEEIVEKLKGELESSDQVREHTSHLEAELEKHMAAASAECQNYAKEVAGLRQLLLESQS 576
Query: 306 --DEASRALQRAHEQTETVRKCLQTTVAELER-QLA---ASRAQVSTAEKEREELKNRLH 359
D A Q+ ++ VR+ L + +E +A AS + AE++ +LK +L
Sbjct: 577 QLDAAKSEAQKQSDELALVRQQLSEMKSHVEDGDIAGAPASSPEAPPAEQDPVQLKTQLE 636
Query: 360 W----------QMKRLTENFEQAQLRILGLQTQVQSLR 387
W Q ++LT FE+AQ LQ +++ LR
Sbjct: 637 WTEAILEDEQTQRQKLTAEFEEAQTSACLLQEELEKLR 674
Score = 34.3 bits (75), Expect = 0.80
Identities = 39/177 (22%), Positives = 79/177 (44%), Gaps = 13/177 (7%)
Query: 242 EKQMALLNQRISQLAENNISLKSEIERLKASVIRTEE--SAL-ANEKRLQEKMHECAQLG 298
+K++ +++ + ++ SL+++ E+ + + E S L ++E ++ K E + L
Sbjct: 222 QKRLDEVSRELCHTQSSHASLRADAEKAQEQQQQMAELHSKLQSSEAEVRSKCEELSGLH 281
Query: 299 GELDRTRDEASRALQRAHE-----QTETVRKC--LQTTVAELERQ---LAASRAQVSTAE 348
G+L R E S+ +R + R +Q + AE ++Q L +QVS E
Sbjct: 282 GQLQEARAENSQLTERIRSIEALLEAGQARDAQDVQASQAEADQQQTRLKELESQVSGLE 341
Query: 349 KEREELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRRTASSTGDGDGENQECTC 405
KE EL+ + Q + + E+ + L T Q+ + S E+++ C
Sbjct: 342 KEAIELREAVEQQKVKNNDLREKNWKAMEALATAEQACKEKLHSLTQAKEESEKQLC 398
Score = 31.9 bits (69), Expect = 4.3
Identities = 38/188 (20%), Positives = 80/188 (42%), Gaps = 8/188 (4%)
Query: 201 QEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNI 260
QE L +++ R ++ ++ L ++L E ++A L Q +S++++ +
Sbjct: 125 QEQLENGPNTQLARLQQENSI---LRDALNQATSQVE-SKQNAELAKLRQELSKVSKELV 180
Query: 261 SLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTE 320
+ + + E A A EK++ + + L + DE SR L
Sbjct: 181 EKSEAVRQDEQQRKALEAKAAAFEKQVLQLQASHRESEEALQKRLDEVSRELCHTQSSHA 240
Query: 321 TVRKCLQTTVAELERQLAA--SRAQVSTAE-KEREELKNRLHWQMKRLTENFEQAQLRIL 377
++R + E ++Q+A S+ Q S AE + + E + LH Q++ Q RI
Sbjct: 241 SLRADAE-KAQEQQQQMAELHSKLQSSEAEVRSKCEELSGLHGQLQEARAENSQLTERIR 299
Query: 378 GLQTQVQS 385
++ +++
Sbjct: 300 SIEALLEA 307
>BC113409-1|AAI13410.1| 1416|Homo sapiens uveal autoantigen with
coiled-coil domains and ankyrin repeats protein.
Length = 1416
Score = 43.6 bits (98), Expect = 0.001
Identities = 30/133 (22%), Positives = 61/133 (45%), Gaps = 5/133 (3%)
Query: 256 AENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRA 315
+EN I LK E+E ++ ++ L + L K+ EC L E +R ++++ +++
Sbjct: 437 SENEI-LKKELEAMRTFCESAKQDRLKLQNELAHKVAECKALALECERVKEDSDEQIKQL 495
Query: 316 HEQTETVRKCLQTTVAELERQ----LAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQ 371
+ + V+K + + ++++ LA S A L L Q+K L +E
Sbjct: 496 EDALKDVQKRMYESEGKVKQMQTHFLALKEHLTSEAASGNHRLTEELKDQLKDLKVKYEG 555
Query: 372 AQLRILGLQTQVQ 384
A + L+ Q++
Sbjct: 556 ASAEVGKLRNQIK 568
Score = 35.1 bits (77), Expect = 0.46
Identities = 47/250 (18%), Positives = 112/250 (44%), Gaps = 28/250 (11%)
Query: 21 RETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMK 80
++ Q ++ E E K + + TH + KE + + + E ++++ +L+ +
Sbjct: 500 KDVQKRMYESEGKVKQMQTH---FLALKEHLTSEAASGN--HRLTEELKDQLKDLKVKYE 554
Query: 81 EQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELA 140
+ ++ R + Q + +VEE +R N R+ +++++ +++ ++K +++
Sbjct: 555 GASAEVGKLRNQIKQNEMIVEEFKRDEGKLIEENKRLQKELSM----CEMEREKKGRKVT 610
Query: 141 PIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLT 200
+ K +L + A+ E+ L+ E+N +K+V + R
Sbjct: 611 EMEGQAKELSAKLALSIPAEKF-ENMKSSLSNEVNEKAKKLVEMERE------------- 656
Query: 201 QEDLFGQSQSEIGRGNKD-QTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENN 259
+S SEI + ++ + V L +KP E + E++ L ++I++L N
Sbjct: 657 ----HEKSLSEIRQLKRELENVKAKLAQHVKPEEHEQVKSRLEQKSGELGKKITELTLKN 712
Query: 260 ISLKSEIERL 269
+L+ EIE++
Sbjct: 713 QTLQKEIEKV 722
Score = 32.3 bits (70), Expect = 3.2
Identities = 70/364 (19%), Positives = 153/364 (42%), Gaps = 27/364 (7%)
Query: 48 KEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQA----QQLVEEQ 103
K++ F + ++R ++ E L E N QL+D KY + ++LVEE
Sbjct: 1034 KKEIFTLQKDLRDKTVLIEKSHEMERALSRKTDELNKQLKDLSQKYTEVKNVKEKLVEEN 1093
Query: 104 RRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIA 163
+Q + +Q ++ +++V+ + + + + LK+ Q R + +Q
Sbjct: 1094 AKQTSEILAVQNLLQKQ-HVPLEQVEALKKSLNGTIENLKEELKSMQ-RCYEKEQQTVTK 1151
Query: 164 EHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHV 223
H + + + + + I + +L +++ +SQ+++ +K Q+
Sbjct: 1152 LHQLLENQKNSSVPLAEHLQIKEAFEKEVGIIKASLREKE--EESQNKMEEVSKLQSEVQ 1209
Query: 224 LLHNSLKPPE--KPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESAL 281
+LK E + + + + L +IS L E +L + E + V+ ++ +
Sbjct: 1210 NTKQALKKLETREVVDLSKYKATKSDLETQISSLNEKLANLNRKYEEVCEEVLHAKKKEI 1269
Query: 282 ANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASR 341
+ K +E +H + E+ ++ ++L E LQ + E +Q+ A
Sbjct: 1270 -SAKDEKELLH--FSIEQEIKDQKERCDKSLTTITE--------LQRRIQESAKQIEAKD 1318
Query: 342 AQVSTAEKEREELKNRLHW--QMKRLTENFEQAQLRILG-LQTQVQSLRRTASSTGDGDG 398
+++ + E LK L+ Q+ + N + Q +++ LQ QV+SL + D D
Sbjct: 1319 NKITELLNDVERLKQALNGLSQLTYTSGNPTKRQSQLIDTLQHQVKSLEQ---QLADADR 1375
Query: 399 ENQE 402
++QE
Sbjct: 1376 QHQE 1379
>BC113407-1|AAI13408.1| 1416|Homo sapiens uveal autoantigen with
coiled-coil domains and ankyrin repeats protein.
Length = 1416
Score = 43.6 bits (98), Expect = 0.001
Identities = 30/133 (22%), Positives = 61/133 (45%), Gaps = 5/133 (3%)
Query: 256 AENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRA 315
+EN I LK E+E ++ ++ L + L K+ EC L E +R ++++ +++
Sbjct: 437 SENEI-LKKELEAMRTFCESAKQDRLKLQNELAHKVAECKALALECERVKEDSDEQIKQL 495
Query: 316 HEQTETVRKCLQTTVAELERQ----LAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQ 371
+ + V+K + + ++++ LA S A L L Q+K L +E
Sbjct: 496 EDALKDVQKRMYESEGKVKQMQTHFLALKEHLTSEAASGNHRLTEELKDQLKDLKVKYEG 555
Query: 372 AQLRILGLQTQVQ 384
A + L+ Q++
Sbjct: 556 ASAEVGKLRNQIK 568
Score = 35.1 bits (77), Expect = 0.46
Identities = 47/250 (18%), Positives = 112/250 (44%), Gaps = 28/250 (11%)
Query: 21 RETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMK 80
++ Q ++ E E K + + TH + KE + + + E ++++ +L+ +
Sbjct: 500 KDVQKRMYESEGKVKQMQTH---FLALKEHLTSEAASGN--HRLTEELKDQLKDLKVKYE 554
Query: 81 EQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELA 140
+ ++ R + Q + +VEE +R N R+ +++++ +++ ++K +++
Sbjct: 555 GASAEVGKLRNQIKQNEMIVEEFKRDEGKLIEENKRLQKELSM----CEMEREKKGRKVT 610
Query: 141 PIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLT 200
+ K +L + A+ E+ L+ E+N +K+V + R
Sbjct: 611 EMEGQAKELSAKLALSIPAEKF-ENMKSSLSNEVNEKAKKLVEMERE------------- 656
Query: 201 QEDLFGQSQSEIGRGNKD-QTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENN 259
+S SEI + ++ + V L +KP E + E++ L ++I++L N
Sbjct: 657 ----HEKSLSEIRQLKRELENVKAKLAQHVKPEEHEQVKSRLEQKSGELGKKITELTLKN 712
Query: 260 ISLKSEIERL 269
+L+ EIE++
Sbjct: 713 QTLQKEIEKV 722
Score = 32.3 bits (70), Expect = 3.2
Identities = 70/364 (19%), Positives = 153/364 (42%), Gaps = 27/364 (7%)
Query: 48 KEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQA----QQLVEEQ 103
K++ F + ++R ++ E L E N QL+D KY + ++LVEE
Sbjct: 1034 KKEIFTLQKDLRDKTVLIEKSHEMERALSRKTDELNKQLKDLSQKYTEVKNVKEKLVEEN 1093
Query: 104 RRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIA 163
+Q + +Q ++ +++V+ + + + + LK+ Q R + +Q
Sbjct: 1094 AKQTSEILAVQNLLQKQ-HVPLEQVEALKKSLNGTIENLKEELKSMQ-RCYEKEQQTVTK 1151
Query: 164 EHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHV 223
H + + + + + I + +L +++ +SQ+++ +K Q+
Sbjct: 1152 LHQLLENQKNSSVPLAEHLQIKEAFEKEVGIIKASLREKE--EESQNKMEEVSKLQSEVQ 1209
Query: 224 LLHNSLKPPE--KPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESAL 281
+LK E + + + + L +IS L E +L + E + V+ ++ +
Sbjct: 1210 NTKQALKKLETREVVDLSKYKATKSDLETQISSLNEKLANLNRKYEEVCEEVLHAKKKEI 1269
Query: 282 ANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASR 341
+ K +E +H + E+ ++ ++L E LQ + E +Q+ A
Sbjct: 1270 -SAKDEKELLH--FSIEQEIKDQKERCDKSLTTITE--------LQRRIQESAKQIEAKD 1318
Query: 342 AQVSTAEKEREELKNRLHW--QMKRLTENFEQAQLRILG-LQTQVQSLRRTASSTGDGDG 398
+++ + E LK L+ Q+ + N + Q +++ LQ QV+SL + D D
Sbjct: 1319 NKITELLNDVERLKQALNGLSQLTYTSGNPTKRQSQLIDTLQHQVKSLEQ---QLADADR 1375
Query: 399 ENQE 402
++QE
Sbjct: 1376 QHQE 1379
>BC016881-1|AAH16881.1| 638|Homo sapiens Unknown (protein for
IMAGE:3914496) protein.
Length = 638
Score = 43.6 bits (98), Expect = 0.001
Identities = 30/133 (22%), Positives = 61/133 (45%), Gaps = 5/133 (3%)
Query: 256 AENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRA 315
+EN I LK E+E ++ ++ L + L K+ EC L E +R ++++ +++
Sbjct: 424 SENEI-LKKELEAMRTFCESAKQDRLKLQNELAHKVAECKALALECERVKEDSDEQIKQL 482
Query: 316 HEQTETVRKCLQTTVAELERQ----LAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQ 371
+ + V+K + + ++++ LA S A L L Q+K L +E
Sbjct: 483 EDALKDVQKRMYESEGKVKQMQTHFLALKEHLTSEAASGNHRLTEELKDQLKDLKVKYEG 542
Query: 372 AQLRILGLQTQVQ 384
A + L+ Q++
Sbjct: 543 ASAEVGKLRNQIK 555
>AL590642-2|CAH70770.1| 862|Homo sapiens CDK5 regulatory subunit
associated protein 2 protein.
Length = 862
Score = 43.6 bits (98), Expect = 0.001
Identities = 49/250 (19%), Positives = 107/250 (42%), Gaps = 15/250 (6%)
Query: 144 DLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQED 203
+L + Q+ +K ++ +++AE ++ R AR+KV + L L+ +T
Sbjct: 116 ELQEREQLLIKASKAVESLAEAGGSEIQRVKEDARKKVQQVEDLLTKRILLLEKDVTAAQ 175
Query: 204 LFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLK 263
+ + ++ + + L + L +K E GD +L+++ + E +SLK
Sbjct: 176 --AELEKAFAGTETEKALRLRLESKLSEMKKMHE--GDLAMALVLDEKDRLIEELKLSLK 231
Query: 264 SEIERLKASVIRTEESALANEKRLQEKMHE-CAQLGGELDRTRDEASRALQRAHEQTETV 322
S+ ++ + A +E ++ CA E +R + A Q+ E
Sbjct: 232 SKEALIQCLKEEKSQMACPDENVSSGELRGLCAAPREEKERETEAAQMEHQKERNSFEER 291
Query: 323 RKCLQTTVAELERQLAASRAQ----------VSTAEKEREELKNRLHWQMKRLTENFEQA 372
+ L+ + E ER++A + ++ A K +E+ L+ ++++L+ F +A
Sbjct: 292 IQALEEDLREKEREIATEKKNSLKRDKAIQGLTMALKSKEKKVEELNSEIEKLSAAFAKA 351
Query: 373 QLRILGLQTQ 382
+ + QTQ
Sbjct: 352 REALQKAQTQ 361
Score = 36.3 bits (80), Expect = 0.20
Identities = 36/157 (22%), Positives = 68/157 (43%), Gaps = 8/157 (5%)
Query: 242 EKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGEL 301
+K+ +RI L E+ + EI K + ++ +++ L+ K + +L E+
Sbjct: 282 QKERNSFEERIQALEEDLREKEREIATEKKNSLKRDKAIQGLTMALKSKEKKVEELNSEI 341
Query: 302 DRTRD---EASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRL 358
++ +A ALQ+A Q + +T ++ E AA R+Q T E +RL
Sbjct: 342 EKLSAAFAKAREALQKAQTQEFQGSEDYETALSGKEALSAALRSQNLTKSTE----NHRL 397
Query: 359 HWQMKRLTENFEQAQLRILGLQTQVQSLRRTASSTGD 395
+K++T+ Q L+ ++ R S GD
Sbjct: 398 RRSIKKITQELSDLQQERERLEKDLEEAHR-EKSKGD 433
>AL590642-1|CAH70769.1| 1893|Homo sapiens CDK5 regulatory subunit
associated protein 2 protein.
Length = 1893
Score = 43.6 bits (98), Expect = 0.001
Identities = 49/250 (19%), Positives = 107/250 (42%), Gaps = 15/250 (6%)
Query: 144 DLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQED 203
+L + Q+ +K ++ +++AE ++ R AR+KV + L L+ +T
Sbjct: 116 ELQEREQLLIKASKAVESLAEAGGSEIQRVKEDARKKVQQVEDLLTKRILLLEKDVTAAQ 175
Query: 204 LFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLK 263
+ + ++ + + L + L +K E GD +L+++ + E +SLK
Sbjct: 176 --AELEKAFAGTETEKALRLRLESKLSEMKKMHE--GDLAMALVLDEKDRLIEELKLSLK 231
Query: 264 SEIERLKASVIRTEESALANEKRLQEKMHE-CAQLGGELDRTRDEASRALQRAHEQTETV 322
S+ ++ + A +E ++ CA E +R + A Q+ E
Sbjct: 232 SKEALIQCLKEEKSQMACPDENVSSGELRGLCAAPREEKERETEAAQMEHQKERNSFEER 291
Query: 323 RKCLQTTVAELERQLAASRAQ----------VSTAEKEREELKNRLHWQMKRLTENFEQA 372
+ L+ + E ER++A + ++ A K +E+ L+ ++++L+ F +A
Sbjct: 292 IQALEEDLREKEREIATEKKNSLKRDKAIQGLTMALKSKEKKVEELNSEIEKLSAAFAKA 351
Query: 373 QLRILGLQTQ 382
+ + QTQ
Sbjct: 352 REALQKAQTQ 361
Score = 36.3 bits (80), Expect = 0.20
Identities = 36/157 (22%), Positives = 68/157 (43%), Gaps = 8/157 (5%)
Query: 242 EKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGEL 301
+K+ +RI L E+ + EI K + ++ +++ L+ K + +L E+
Sbjct: 282 QKERNSFEERIQALEEDLREKEREIATEKKNSLKRDKAIQGLTMALKSKEKKVEELNSEI 341
Query: 302 DRTRD---EASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRL 358
++ +A ALQ+A Q + +T ++ E AA R+Q T E +RL
Sbjct: 342 EKLSAAFAKAREALQKAQTQEFQGSEDYETALSGKEALSAALRSQNLTKSTE----NHRL 397
Query: 359 HWQMKRLTENFEQAQLRILGLQTQVQSLRRTASSTGD 395
+K++T+ Q L+ ++ R S GD
Sbjct: 398 RRSIKKITQELSDLQQERERLEKDLEEAHR-EKSKGD 433
Score = 32.7 bits (71), Expect = 2.4
Identities = 35/144 (24%), Positives = 66/144 (45%), Gaps = 13/144 (9%)
Query: 27 LRELEMKFEGLATHTNMLM--GSKEQAFEQEV--NVRALKQCYREAREEIDELRTLMKEQ 82
L L+ ++ + L GS+++ Q++ VR Q +EE+ +LR + Q
Sbjct: 1491 LEHLQREYASVKEENERLQKEGSEKERHNQQLIQEVRCSGQELSRVQEEV-KLRQQLLSQ 1549
Query: 83 NDQ-LQDYRVKYLQAQQLVEEQRRQXXXX-----XXXNTRISEQINLEIQRVKLKFQEKL 136
ND+ LQ RV+ ++L EE RR R + +EIQ ++L+ + +
Sbjct: 1550 NDKLLQSLRVELKAYEKLDEEHRRLREASGEGWKGQDPFRDLHSLLMEIQALRLQLERSI 1609
Query: 137 QELAPIPDLLKATQMRLKDAQQAQ 160
+ + + LK + + A++AQ
Sbjct: 1610 ETSSTLQSRLK--EQLARGAEKAQ 1631
Score = 30.7 bits (66), Expect = 9.8
Identities = 20/107 (18%), Positives = 46/107 (42%)
Query: 285 KRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQV 344
KRL+E + +L +L+R E + + L + + L +Q A A +
Sbjct: 1407 KRLEESIKTNEKLRKQLERQGSEFVQGSTSIFASGSELHSSLTSEIHFLRKQNQALNAML 1466
Query: 345 STAEKEREELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRRTAS 391
+++++ ++L + R T + E Q ++ + + L++ S
Sbjct: 1467 IKGSRDKQKENDKLRESLSRKTVSLEHLQREYASVKEENERLQKEGS 1513
>AL391870-2|CAI40925.1| 1893|Homo sapiens CDK5 regulatory subunit
associated protein 2 protein.
Length = 1893
Score = 43.6 bits (98), Expect = 0.001
Identities = 49/250 (19%), Positives = 107/250 (42%), Gaps = 15/250 (6%)
Query: 144 DLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQED 203
+L + Q+ +K ++ +++AE ++ R AR+KV + L L+ +T
Sbjct: 116 ELQEREQLLIKASKAVESLAEAGGSEIQRVKEDARKKVQQVEDLLTKRILLLEKDVTAAQ 175
Query: 204 LFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLK 263
+ + ++ + + L + L +K E GD +L+++ + E +SLK
Sbjct: 176 --AELEKAFAGTETEKALRLRLESKLSEMKKMHE--GDLAMALVLDEKDRLIEELKLSLK 231
Query: 264 SEIERLKASVIRTEESALANEKRLQEKMHE-CAQLGGELDRTRDEASRALQRAHEQTETV 322
S+ ++ + A +E ++ CA E +R + A Q+ E
Sbjct: 232 SKEALIQCLKEEKSQMACPDENVSSGELRGLCAAPREEKERETEAAQMEHQKERNSFEER 291
Query: 323 RKCLQTTVAELERQLAASRAQ----------VSTAEKEREELKNRLHWQMKRLTENFEQA 372
+ L+ + E ER++A + ++ A K +E+ L+ ++++L+ F +A
Sbjct: 292 IQALEEDLREKEREIATEKKNSLKRDKAIQGLTMALKSKEKKVEELNSEIEKLSAAFAKA 351
Query: 373 QLRILGLQTQ 382
+ + QTQ
Sbjct: 352 REALQKAQTQ 361
Score = 36.3 bits (80), Expect = 0.20
Identities = 36/157 (22%), Positives = 68/157 (43%), Gaps = 8/157 (5%)
Query: 242 EKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGEL 301
+K+ +RI L E+ + EI K + ++ +++ L+ K + +L E+
Sbjct: 282 QKERNSFEERIQALEEDLREKEREIATEKKNSLKRDKAIQGLTMALKSKEKKVEELNSEI 341
Query: 302 DRTRD---EASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRL 358
++ +A ALQ+A Q + +T ++ E AA R+Q T E +RL
Sbjct: 342 EKLSAAFAKAREALQKAQTQEFQGSEDYETALSGKEALSAALRSQNLTKSTE----NHRL 397
Query: 359 HWQMKRLTENFEQAQLRILGLQTQVQSLRRTASSTGD 395
+K++T+ Q L+ ++ R S GD
Sbjct: 398 RRSIKKITQELSDLQQERERLEKDLEEAHR-EKSKGD 433
Score = 32.7 bits (71), Expect = 2.4
Identities = 35/144 (24%), Positives = 66/144 (45%), Gaps = 13/144 (9%)
Query: 27 LRELEMKFEGLATHTNMLM--GSKEQAFEQEV--NVRALKQCYREAREEIDELRTLMKEQ 82
L L+ ++ + L GS+++ Q++ VR Q +EE+ +LR + Q
Sbjct: 1491 LEHLQREYASVKEENERLQKEGSEKERHNQQLIQEVRCSGQELSRVQEEV-KLRQQLLSQ 1549
Query: 83 NDQ-LQDYRVKYLQAQQLVEEQRRQXXXX-----XXXNTRISEQINLEIQRVKLKFQEKL 136
ND+ LQ RV+ ++L EE RR R + +EIQ ++L+ + +
Sbjct: 1550 NDKLLQSLRVELKAYEKLDEEHRRLREASGEGWKGQDPFRDLHSLLMEIQALRLQLERSI 1609
Query: 137 QELAPIPDLLKATQMRLKDAQQAQ 160
+ + + LK + + A++AQ
Sbjct: 1610 ETSSTLQSRLK--EQLARGAEKAQ 1631
Score = 30.7 bits (66), Expect = 9.8
Identities = 20/107 (18%), Positives = 46/107 (42%)
Query: 285 KRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQV 344
KRL+E + +L +L+R E + + L + + L +Q A A +
Sbjct: 1407 KRLEESIKTNEKLRKQLERQGSEFVQGSTSIFASGSELHSSLTSEIHFLRKQNQALNAML 1466
Query: 345 STAEKEREELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRRTAS 391
+++++ ++L + R T + E Q ++ + + L++ S
Sbjct: 1467 IKGSRDKQKENDKLRESLSRKTVSLEHLQREYASVKEENERLQKEGS 1513
>AL391870-1|CAI40926.1| 862|Homo sapiens CDK5 regulatory subunit
associated protein 2 protein.
Length = 862
Score = 43.6 bits (98), Expect = 0.001
Identities = 49/250 (19%), Positives = 107/250 (42%), Gaps = 15/250 (6%)
Query: 144 DLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQED 203
+L + Q+ +K ++ +++AE ++ R AR+KV + L L+ +T
Sbjct: 116 ELQEREQLLIKASKAVESLAEAGGSEIQRVKEDARKKVQQVEDLLTKRILLLEKDVTAAQ 175
Query: 204 LFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLK 263
+ + ++ + + L + L +K E GD +L+++ + E +SLK
Sbjct: 176 --AELEKAFAGTETEKALRLRLESKLSEMKKMHE--GDLAMALVLDEKDRLIEELKLSLK 231
Query: 264 SEIERLKASVIRTEESALANEKRLQEKMHE-CAQLGGELDRTRDEASRALQRAHEQTETV 322
S+ ++ + A +E ++ CA E +R + A Q+ E
Sbjct: 232 SKEALIQCLKEEKSQMACPDENVSSGELRGLCAAPREEKERETEAAQMEHQKERNSFEER 291
Query: 323 RKCLQTTVAELERQLAASRAQ----------VSTAEKEREELKNRLHWQMKRLTENFEQA 372
+ L+ + E ER++A + ++ A K +E+ L+ ++++L+ F +A
Sbjct: 292 IQALEEDLREKEREIATEKKNSLKRDKAIQGLTMALKSKEKKVEELNSEIEKLSAAFAKA 351
Query: 373 QLRILGLQTQ 382
+ + QTQ
Sbjct: 352 REALQKAQTQ 361
Score = 36.3 bits (80), Expect = 0.20
Identities = 36/157 (22%), Positives = 68/157 (43%), Gaps = 8/157 (5%)
Query: 242 EKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGEL 301
+K+ +RI L E+ + EI K + ++ +++ L+ K + +L E+
Sbjct: 282 QKERNSFEERIQALEEDLREKEREIATEKKNSLKRDKAIQGLTMALKSKEKKVEELNSEI 341
Query: 302 DRTRD---EASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRL 358
++ +A ALQ+A Q + +T ++ E AA R+Q T E +RL
Sbjct: 342 EKLSAAFAKAREALQKAQTQEFQGSEDYETALSGKEALSAALRSQNLTKSTE----NHRL 397
Query: 359 HWQMKRLTENFEQAQLRILGLQTQVQSLRRTASSTGD 395
+K++T+ Q L+ ++ R S GD
Sbjct: 398 RRSIKKITQELSDLQQERERLEKDLEEAHR-EKSKGD 433
>AL353736-2|CAI40654.1| 862|Homo sapiens CDK5 regulatory subunit
associated protein 2 protein.
Length = 862
Score = 43.6 bits (98), Expect = 0.001
Identities = 49/250 (19%), Positives = 107/250 (42%), Gaps = 15/250 (6%)
Query: 144 DLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQED 203
+L + Q+ +K ++ +++AE ++ R AR+KV + L L+ +T
Sbjct: 116 ELQEREQLLIKASKAVESLAEAGGSEIQRVKEDARKKVQQVEDLLTKRILLLEKDVTAAQ 175
Query: 204 LFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLK 263
+ + ++ + + L + L +K E GD +L+++ + E +SLK
Sbjct: 176 --AELEKAFAGTETEKALRLRLESKLSEMKKMHE--GDLAMALVLDEKDRLIEELKLSLK 231
Query: 264 SEIERLKASVIRTEESALANEKRLQEKMHE-CAQLGGELDRTRDEASRALQRAHEQTETV 322
S+ ++ + A +E ++ CA E +R + A Q+ E
Sbjct: 232 SKEALIQCLKEEKSQMACPDENVSSGELRGLCAAPREEKERETEAAQMEHQKERNSFEER 291
Query: 323 RKCLQTTVAELERQLAASRAQ----------VSTAEKEREELKNRLHWQMKRLTENFEQA 372
+ L+ + E ER++A + ++ A K +E+ L+ ++++L+ F +A
Sbjct: 292 IQALEEDLREKEREIATEKKNSLKRDKAIQGLTMALKSKEKKVEELNSEIEKLSAAFAKA 351
Query: 373 QLRILGLQTQ 382
+ + QTQ
Sbjct: 352 REALQKAQTQ 361
Score = 36.3 bits (80), Expect = 0.20
Identities = 36/157 (22%), Positives = 68/157 (43%), Gaps = 8/157 (5%)
Query: 242 EKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGEL 301
+K+ +RI L E+ + EI K + ++ +++ L+ K + +L E+
Sbjct: 282 QKERNSFEERIQALEEDLREKEREIATEKKNSLKRDKAIQGLTMALKSKEKKVEELNSEI 341
Query: 302 DRTRD---EASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRL 358
++ +A ALQ+A Q + +T ++ E AA R+Q T E +RL
Sbjct: 342 EKLSAAFAKAREALQKAQTQEFQGSEDYETALSGKEALSAALRSQNLTKSTE----NHRL 397
Query: 359 HWQMKRLTENFEQAQLRILGLQTQVQSLRRTASSTGD 395
+K++T+ Q L+ ++ R S GD
Sbjct: 398 RRSIKKITQELSDLQQERERLEKDLEEAHR-EKSKGD 433
>AL353736-1|CAI40653.1| 1893|Homo sapiens CDK5 regulatory subunit
associated protein 2 protein.
Length = 1893
Score = 43.6 bits (98), Expect = 0.001
Identities = 49/250 (19%), Positives = 107/250 (42%), Gaps = 15/250 (6%)
Query: 144 DLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQED 203
+L + Q+ +K ++ +++AE ++ R AR+KV + L L+ +T
Sbjct: 116 ELQEREQLLIKASKAVESLAEAGGSEIQRVKEDARKKVQQVEDLLTKRILLLEKDVTAAQ 175
Query: 204 LFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLK 263
+ + ++ + + L + L +K E GD +L+++ + E +SLK
Sbjct: 176 --AELEKAFAGTETEKALRLRLESKLSEMKKMHE--GDLAMALVLDEKDRLIEELKLSLK 231
Query: 264 SEIERLKASVIRTEESALANEKRLQEKMHE-CAQLGGELDRTRDEASRALQRAHEQTETV 322
S+ ++ + A +E ++ CA E +R + A Q+ E
Sbjct: 232 SKEALIQCLKEEKSQMACPDENVSSGELRGLCAAPREEKERETEAAQMEHQKERNSFEER 291
Query: 323 RKCLQTTVAELERQLAASRAQ----------VSTAEKEREELKNRLHWQMKRLTENFEQA 372
+ L+ + E ER++A + ++ A K +E+ L+ ++++L+ F +A
Sbjct: 292 IQALEEDLREKEREIATEKKNSLKRDKAIQGLTMALKSKEKKVEELNSEIEKLSAAFAKA 351
Query: 373 QLRILGLQTQ 382
+ + QTQ
Sbjct: 352 REALQKAQTQ 361
Score = 36.3 bits (80), Expect = 0.20
Identities = 36/157 (22%), Positives = 68/157 (43%), Gaps = 8/157 (5%)
Query: 242 EKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGEL 301
+K+ +RI L E+ + EI K + ++ +++ L+ K + +L E+
Sbjct: 282 QKERNSFEERIQALEEDLREKEREIATEKKNSLKRDKAIQGLTMALKSKEKKVEELNSEI 341
Query: 302 DRTRD---EASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRL 358
++ +A ALQ+A Q + +T ++ E AA R+Q T E +RL
Sbjct: 342 EKLSAAFAKAREALQKAQTQEFQGSEDYETALSGKEALSAALRSQNLTKSTE----NHRL 397
Query: 359 HWQMKRLTENFEQAQLRILGLQTQVQSLRRTASSTGD 395
+K++T+ Q L+ ++ R S GD
Sbjct: 398 RRSIKKITQELSDLQQERERLEKDLEEAHR-EKSKGD 433
Score = 32.7 bits (71), Expect = 2.4
Identities = 35/144 (24%), Positives = 66/144 (45%), Gaps = 13/144 (9%)
Query: 27 LRELEMKFEGLATHTNMLM--GSKEQAFEQEV--NVRALKQCYREAREEIDELRTLMKEQ 82
L L+ ++ + L GS+++ Q++ VR Q +EE+ +LR + Q
Sbjct: 1491 LEHLQREYASVKEENERLQKEGSEKERHNQQLIQEVRCSGQELSRVQEEV-KLRQQLLSQ 1549
Query: 83 NDQ-LQDYRVKYLQAQQLVEEQRRQXXXX-----XXXNTRISEQINLEIQRVKLKFQEKL 136
ND+ LQ RV+ ++L EE RR R + +EIQ ++L+ + +
Sbjct: 1550 NDKLLQSLRVELKAYEKLDEEHRRLREASGEGWKGQDPFRDLHSLLMEIQALRLQLERSI 1609
Query: 137 QELAPIPDLLKATQMRLKDAQQAQ 160
+ + + LK + + A++AQ
Sbjct: 1610 ETSSTLQSRLK--EQLARGAEKAQ 1631
Score = 30.7 bits (66), Expect = 9.8
Identities = 20/107 (18%), Positives = 46/107 (42%)
Query: 285 KRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQV 344
KRL+E + +L +L+R E + + L + + L +Q A A +
Sbjct: 1407 KRLEESIKTNEKLRKQLERQGSEFVQGSTSIFASGSELHSSLTSEIHFLRKQNQALNAML 1466
Query: 345 STAEKEREELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRRTAS 391
+++++ ++L + R T + E Q ++ + + L++ S
Sbjct: 1467 IKGSRDKQKENDKLRESLSRKTVSLEHLQREYASVKEENERLQKEGS 1513
>AL138836-2|CAI16963.1| 1893|Homo sapiens CDK5 regulatory subunit
associated protein 2 protein.
Length = 1893
Score = 43.6 bits (98), Expect = 0.001
Identities = 49/250 (19%), Positives = 107/250 (42%), Gaps = 15/250 (6%)
Query: 144 DLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQED 203
+L + Q+ +K ++ +++AE ++ R AR+KV + L L+ +T
Sbjct: 116 ELQEREQLLIKASKAVESLAEAGGSEIQRVKEDARKKVQQVEDLLTKRILLLEKDVTAAQ 175
Query: 204 LFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLK 263
+ + ++ + + L + L +K E GD +L+++ + E +SLK
Sbjct: 176 --AELEKAFAGTETEKALRLRLESKLSEMKKMHE--GDLAMALVLDEKDRLIEELKLSLK 231
Query: 264 SEIERLKASVIRTEESALANEKRLQEKMHE-CAQLGGELDRTRDEASRALQRAHEQTETV 322
S+ ++ + A +E ++ CA E +R + A Q+ E
Sbjct: 232 SKEALIQCLKEEKSQMACPDENVSSGELRGLCAAPREEKERETEAAQMEHQKERNSFEER 291
Query: 323 RKCLQTTVAELERQLAASRAQ----------VSTAEKEREELKNRLHWQMKRLTENFEQA 372
+ L+ + E ER++A + ++ A K +E+ L+ ++++L+ F +A
Sbjct: 292 IQALEEDLREKEREIATEKKNSLKRDKAIQGLTMALKSKEKKVEELNSEIEKLSAAFAKA 351
Query: 373 QLRILGLQTQ 382
+ + QTQ
Sbjct: 352 REALQKAQTQ 361
Score = 36.3 bits (80), Expect = 0.20
Identities = 36/157 (22%), Positives = 68/157 (43%), Gaps = 8/157 (5%)
Query: 242 EKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGEL 301
+K+ +RI L E+ + EI K + ++ +++ L+ K + +L E+
Sbjct: 282 QKERNSFEERIQALEEDLREKEREIATEKKNSLKRDKAIQGLTMALKSKEKKVEELNSEI 341
Query: 302 DRTRD---EASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRL 358
++ +A ALQ+A Q + +T ++ E AA R+Q T E +RL
Sbjct: 342 EKLSAAFAKAREALQKAQTQEFQGSEDYETALSGKEALSAALRSQNLTKSTE----NHRL 397
Query: 359 HWQMKRLTENFEQAQLRILGLQTQVQSLRRTASSTGD 395
+K++T+ Q L+ ++ R S GD
Sbjct: 398 RRSIKKITQELSDLQQERERLEKDLEEAHR-EKSKGD 433
Score = 32.7 bits (71), Expect = 2.4
Identities = 35/144 (24%), Positives = 66/144 (45%), Gaps = 13/144 (9%)
Query: 27 LRELEMKFEGLATHTNMLM--GSKEQAFEQEV--NVRALKQCYREAREEIDELRTLMKEQ 82
L L+ ++ + L GS+++ Q++ VR Q +EE+ +LR + Q
Sbjct: 1491 LEHLQREYASVKEENERLQKEGSEKERHNQQLIQEVRCSGQELSRVQEEV-KLRQQLLSQ 1549
Query: 83 NDQ-LQDYRVKYLQAQQLVEEQRRQXXXX-----XXXNTRISEQINLEIQRVKLKFQEKL 136
ND+ LQ RV+ ++L EE RR R + +EIQ ++L+ + +
Sbjct: 1550 NDKLLQSLRVELKAYEKLDEEHRRLREASGEGWKGQDPFRDLHSLLMEIQALRLQLERSI 1609
Query: 137 QELAPIPDLLKATQMRLKDAQQAQ 160
+ + + LK + + A++AQ
Sbjct: 1610 ETSSTLQSRLK--EQLARGAEKAQ 1631
Score = 30.7 bits (66), Expect = 9.8
Identities = 20/107 (18%), Positives = 46/107 (42%)
Query: 285 KRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQV 344
KRL+E + +L +L+R E + + L + + L +Q A A +
Sbjct: 1407 KRLEESIKTNEKLRKQLERQGSEFVQGSTSIFASGSELHSSLTSEIHFLRKQNQALNAML 1466
Query: 345 STAEKEREELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRRTAS 391
+++++ ++L + R T + E Q ++ + + L++ S
Sbjct: 1467 IKGSRDKQKENDKLRESLSRKTVSLEHLQREYASVKEENERLQKEGS 1513
>AL138836-1|CAI16964.1| 862|Homo sapiens CDK5 regulatory subunit
associated protein 2 protein.
Length = 862
Score = 43.6 bits (98), Expect = 0.001
Identities = 49/250 (19%), Positives = 107/250 (42%), Gaps = 15/250 (6%)
Query: 144 DLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQED 203
+L + Q+ +K ++ +++AE ++ R AR+KV + L L+ +T
Sbjct: 116 ELQEREQLLIKASKAVESLAEAGGSEIQRVKEDARKKVQQVEDLLTKRILLLEKDVTAAQ 175
Query: 204 LFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLK 263
+ + ++ + + L + L +K E GD +L+++ + E +SLK
Sbjct: 176 --AELEKAFAGTETEKALRLRLESKLSEMKKMHE--GDLAMALVLDEKDRLIEELKLSLK 231
Query: 264 SEIERLKASVIRTEESALANEKRLQEKMHE-CAQLGGELDRTRDEASRALQRAHEQTETV 322
S+ ++ + A +E ++ CA E +R + A Q+ E
Sbjct: 232 SKEALIQCLKEEKSQMACPDENVSSGELRGLCAAPREEKERETEAAQMEHQKERNSFEER 291
Query: 323 RKCLQTTVAELERQLAASRAQ----------VSTAEKEREELKNRLHWQMKRLTENFEQA 372
+ L+ + E ER++A + ++ A K +E+ L+ ++++L+ F +A
Sbjct: 292 IQALEEDLREKEREIATEKKNSLKRDKAIQGLTMALKSKEKKVEELNSEIEKLSAAFAKA 351
Query: 373 QLRILGLQTQ 382
+ + QTQ
Sbjct: 352 REALQKAQTQ 361
Score = 36.3 bits (80), Expect = 0.20
Identities = 36/157 (22%), Positives = 68/157 (43%), Gaps = 8/157 (5%)
Query: 242 EKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGEL 301
+K+ +RI L E+ + EI K + ++ +++ L+ K + +L E+
Sbjct: 282 QKERNSFEERIQALEEDLREKEREIATEKKNSLKRDKAIQGLTMALKSKEKKVEELNSEI 341
Query: 302 DRTRD---EASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRL 358
++ +A ALQ+A Q + +T ++ E AA R+Q T E +RL
Sbjct: 342 EKLSAAFAKAREALQKAQTQEFQGSEDYETALSGKEALSAALRSQNLTKSTE----NHRL 397
Query: 359 HWQMKRLTENFEQAQLRILGLQTQVQSLRRTASSTGD 395
+K++T+ Q L+ ++ R S GD
Sbjct: 398 RRSIKKITQELSDLQQERERLEKDLEEAHR-EKSKGD 433
>AK055435-1|BAB70922.1| 634|Homo sapiens protein ( Homo sapiens
cDNA FLJ30873 fis, clone FEBRA2004325, moderately
similar to Canis familiaris mRNA for C3VS protein. ).
Length = 634
Score = 43.6 bits (98), Expect = 0.001
Identities = 30/133 (22%), Positives = 61/133 (45%), Gaps = 5/133 (3%)
Query: 256 AENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRA 315
+EN I LK E+E ++ ++ L + L K+ EC L E +R ++++ +++
Sbjct: 424 SENEI-LKKELEAMRTFCESAKQDRLKLQNELAHKVAECKALALECERVKEDSDEQIKQL 482
Query: 316 HEQTETVRKCLQTTVAELERQ----LAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQ 371
+ + V+K + + ++++ LA S A L L Q+K L +E
Sbjct: 483 EDALKDVQKRMYESEGKVKQMQTHFLALKEHLTSEAASGNHRLTEELKDQLKDLKVKYEG 542
Query: 372 AQLRILGLQTQVQ 384
A + L+ Q++
Sbjct: 543 ASAEVGKLRNQIK 555
>AF515282-1|AAP46636.1| 3336|Homo sapiens pericentrin B protein.
Length = 3336
Score = 43.6 bits (98), Expect = 0.001
Identities = 45/141 (31%), Positives = 66/141 (46%), Gaps = 18/141 (12%)
Query: 252 ISQLAENNISLK------SEIERLKASVIRTEESALANEKRLQ-EKMHECAQLGGELDRT 304
+ +L E N SLK SEIE LKA++ +E N+KRLQ EK E QL +++
Sbjct: 1694 LRELEEENTSLKVIYTRSSEIEELKATIENLQE----NQKRLQKEKAEEIEQLHEVIEKL 1749
Query: 305 RDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKE-----REELKNRLH 359
+ E S HE +++ LQ+ + L Q R Q E E +E L L
Sbjct: 1750 QHELSLMGPVVHEVSDSQAGSLQSEL--LCSQAGGPRGQALQGELEAALEAKEALSRLLA 1807
Query: 360 WQMKRLTENFEQAQLRILGLQ 380
Q +R ++ E Q R+ G +
Sbjct: 1808 DQERRHSQALEALQQRLQGAE 1828
Score = 36.7 bits (81), Expect = 0.15
Identities = 30/115 (26%), Positives = 58/115 (50%), Gaps = 3/115 (2%)
Query: 246 ALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTR 305
++L+ + ++L L+SE + +A + EE L + +R + +L L+ R
Sbjct: 2639 SMLSSKENELKAALQELESEQGKGRALQSQLEEEQLRHLQRESQSAKALEELRASLETQR 2698
Query: 306 DEASR-ALQRAHEQT--ETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNR 357
++SR + HEQT + ++K L+ + E LA R+Q+S +K+ K+R
Sbjct: 2699 AQSSRLCVALKHEQTAKDNLQKELRIEHSRCEALLAQERSQLSELQKDLAAEKSR 2753
Score = 31.5 bits (68), Expect = 5.6
Identities = 28/133 (21%), Positives = 58/133 (43%), Gaps = 13/133 (9%)
Query: 249 NQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQ--------LGGE 300
N+ + + ++ LK ++E++K ++I + L N K+ E M + Q + E
Sbjct: 699 NRNLYEKLQHETRLKDDLEKVKHNLIEDHQKELNNAKQKTELMKQEFQRKETDWKVMKEE 758
Query: 301 LDRTRDEASRAL-----QRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELK 355
L R +E + ++A + +T+ + AE+ + AQ+ E+ E +
Sbjct: 759 LQREAEEKLTLMLLELREKAESEKQTIINKFELREAEMRQLQDQQAAQILDLERSLTEQQ 818
Query: 356 NRLHWQMKRLTEN 368
RL + LT +
Sbjct: 819 GRLQQLEQDLTSD 831
>AF448860-1|AAP41926.1| 1893|Homo sapiens hypothetical protein
protein.
Length = 1893
Score = 43.6 bits (98), Expect = 0.001
Identities = 49/250 (19%), Positives = 107/250 (42%), Gaps = 15/250 (6%)
Query: 144 DLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQED 203
+L + Q+ +K ++ +++AE ++ R AR+KV + L L+ +T
Sbjct: 116 ELQEREQLLIKASKAVESLAEAGGSEIQRVKEDARKKVQQVEDLLTKRILLLEKDVTAAQ 175
Query: 204 LFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLK 263
+ + ++ + + L + L +K E GD +L+++ + E +SLK
Sbjct: 176 --AELEKAFAGTETEKALRLRLESKLSEMKKMHE--GDLAMALVLDEKDRLIEELKLSLK 231
Query: 264 SEIERLKASVIRTEESALANEKRLQEKMHE-CAQLGGELDRTRDEASRALQRAHEQTETV 322
S+ ++ + A +E ++ CA E +R + A Q+ E
Sbjct: 232 SKEALIQCLKEEKSQMACPDENVSSGELRGLCAAPREEKERETEAAQMEHQKERNSFEER 291
Query: 323 RKCLQTTVAELERQLAASRAQ----------VSTAEKEREELKNRLHWQMKRLTENFEQA 372
+ L+ + E ER++A + ++ A K +E+ L+ ++++L+ F +A
Sbjct: 292 IQALEEDLREKEREIATEKKNSLKRDKAIQGLTMALKSKEKKVEELNSEIEKLSAAFAKA 351
Query: 373 QLRILGLQTQ 382
+ + QTQ
Sbjct: 352 REALQKAQTQ 361
Score = 36.3 bits (80), Expect = 0.20
Identities = 36/157 (22%), Positives = 68/157 (43%), Gaps = 8/157 (5%)
Query: 242 EKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGEL 301
+K+ +RI L E+ + EI K + ++ +++ L+ K + +L E+
Sbjct: 282 QKERNSFEERIQALEEDLREKEREIATEKKNSLKRDKAIQGLTMALKSKEKKVEELNSEI 341
Query: 302 DRTRD---EASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTAEKEREELKNRL 358
++ +A ALQ+A Q + +T ++ E AA R+Q T E +RL
Sbjct: 342 EKLSAAFAKAREALQKAQTQEFQGSEDYETALSGKEALSAALRSQNLTKSTE----NHRL 397
Query: 359 HWQMKRLTENFEQAQLRILGLQTQVQSLRRTASSTGD 395
+K++T+ Q L+ ++ R S GD
Sbjct: 398 RRSIKKITQELSDLQQERERLEKDLEEAHR-EKSKGD 433
Score = 32.7 bits (71), Expect = 2.4
Identities = 35/144 (24%), Positives = 66/144 (45%), Gaps = 13/144 (9%)
Query: 27 LRELEMKFEGLATHTNMLM--GSKEQAFEQEV--NVRALKQCYREAREEIDELRTLMKEQ 82
L L+ ++ + L GS+++ Q++ VR Q +EE+ +LR + Q
Sbjct: 1491 LEHLQREYASVKEENERLQKEGSEKERHNQQLIQEVRCSGQELSRVQEEV-KLRQQLLSQ 1549
Query: 83 NDQ-LQDYRVKYLQAQQLVEEQRRQXXXX-----XXXNTRISEQINLEIQRVKLKFQEKL 136
ND+ LQ RV+ ++L EE RR R + +EIQ ++L+ + +
Sbjct: 1550 NDKLLQSLRVELKAYEKLDEEHRRLREASGEGWKGQDPFRDLHSLLMEIQALRLQLERSI 1609
Query: 137 QELAPIPDLLKATQMRLKDAQQAQ 160
+ + + LK + + A++AQ
Sbjct: 1610 ETSSTLQSRLK--EQLARGAEKAQ 1631
Score = 30.7 bits (66), Expect = 9.8
Identities = 20/107 (18%), Positives = 46/107 (42%)
Query: 285 KRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQV 344
KRL+E + +L +L+R E + + L + + L +Q A A +
Sbjct: 1407 KRLEESIKTNEKLRKQLERQGSEFVQGSTSIFASGSELHSSLTSEIHFLRKQNQALNAML 1466
Query: 345 STAEKEREELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRRTAS 391
+++++ ++L + R T + E Q ++ + + L++ S
Sbjct: 1467 IKGSRDKQKENDKLRESLSRKTVSLEHLQREYASVKEENERLQKEGS 1513
>AF322916-1|AAG49577.1| 1416|Homo sapiens uveal autoantigen protein.
Length = 1416
Score = 43.6 bits (98), Expect = 0.001
Identities = 30/133 (22%), Positives = 61/133 (45%), Gaps = 5/133 (3%)
Query: 256 AENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRA 315
+EN I LK E+E ++ ++ L + L K+ EC L E +R ++++ +++
Sbjct: 437 SENEI-LKKELEAMRTFCESAKQDRLKLQNELAHKVAECKALALECERVKEDSDEQIKQL 495
Query: 316 HEQTETVRKCLQTTVAELERQ----LAASRAQVSTAEKEREELKNRLHWQMKRLTENFEQ 371
+ + V+K + + ++++ LA S A L L Q+K L +E
Sbjct: 496 EDALKDVQKRMYESEGKVKQMQTHFLALKEHLTSEAASGNHRLTEELKDQLKDLKVKYEG 555
Query: 372 AQLRILGLQTQVQ 384
A + L+ Q++
Sbjct: 556 ASAEVGKLRNQIK 568
Score = 35.1 bits (77), Expect = 0.46
Identities = 47/250 (18%), Positives = 112/250 (44%), Gaps = 28/250 (11%)
Query: 21 RETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELRTLMK 80
++ Q ++ E E K + + TH + KE + + + E ++++ +L+ +
Sbjct: 500 KDVQKRMYESEGKVKQMQTH---FLALKEHLTSEAASGN--HRLTEELKDQLKDLKVKYE 554
Query: 81 EQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELA 140
+ ++ R + Q + +VEE +R N R+ +++++ +++ ++K +++
Sbjct: 555 GASAEVGKLRNQIKQNEMIVEEFKRDEGKLIEENKRLQKELSM----CEMEREKKGRKVT 610
Query: 141 PIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLT 200
+ K +L + A+ E+ L+ E+N +K+V + R
Sbjct: 611 EMEGQAKELSAKLALSIPAEKF-ENMKSSLSNEVNEKAKKLVEMERE------------- 656
Query: 201 QEDLFGQSQSEIGRGNKD-QTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENN 259
+S SEI + ++ + V L +KP E + E++ L ++I++L N
Sbjct: 657 ----HEKSLSEIRQLKRELENVKAKLAQHVKPEEHEQVKSRLEQKSGELGKKITELTLKN 712
Query: 260 ISLKSEIERL 269
+L+ EIE++
Sbjct: 713 QTLQKEIEKV 722
Score = 32.3 bits (70), Expect = 3.2
Identities = 70/364 (19%), Positives = 153/364 (42%), Gaps = 27/364 (7%)
Query: 48 KEQAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQA----QQLVEEQ 103
K++ F + ++R ++ E L E N QL+D KY + ++LVEE
Sbjct: 1034 KKEIFTLQKDLRDKTVLIEKSHEMERALSRKTDELNKQLKDLSQKYTEVKNVKEKLVEEN 1093
Query: 104 RRQXXXXXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDAQQAQAIA 163
+Q + +Q ++ +++V+ + + + + LK+ Q R + +Q
Sbjct: 1094 AKQTSEILAVQNLLQKQ-HVPLEQVEALKKSLNGTIENLKEELKSMQ-RCYEKEQQTVTK 1151
Query: 164 EHNAEQLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHV 223
H + + + + + I + +L +++ +SQ+++ +K Q+
Sbjct: 1152 LHQLLENQKNSSVPLAEHLQIKEAFEKEVGIIKASLREKE--EESQNKMEEVSKLQSEVQ 1209
Query: 224 LLHNSLKPPE--KPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESAL 281
+LK E + + + + L +IS L E +L + E + V+ ++ +
Sbjct: 1210 NTKQALKKLETREVVDLSKYKATKSDLETQISSLNEKLANLNRKYEEVCEEVLHAKKKEI 1269
Query: 282 ANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQLAASR 341
+ K +E +H + E+ ++ ++L E LQ + E +Q+ A
Sbjct: 1270 -SAKDEKELLH--FSIEQEIKDQKERCDKSLTTITE--------LQRRIQESAKQIEAKD 1318
Query: 342 AQVSTAEKEREELKNRLHW--QMKRLTENFEQAQLRILG-LQTQVQSLRRTASSTGDGDG 398
+++ + E LK L+ Q+ + N + Q +++ LQ QV+SL + D D
Sbjct: 1319 NKITELLNDVERLKQALNGLSQLTYTSGNPTKRQSQLIDTLQHQVKSLEQ---QLADADR 1375
Query: 399 ENQE 402
++QE
Sbjct: 1376 QHQE 1379
>AF155115-1|AAD42881.1| 472|Homo sapiens NY-REN-58 antigen protein.
Length = 472
Score = 43.6 bits (98), Expect = 0.001
Identities = 65/348 (18%), Positives = 136/348 (39%), Gaps = 13/348 (3%)
Query: 50 QAFEQEVNVRALKQCYREAREEIDELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXX 109
Q E + VR+L + A + L ++ ++Q K +A++ + +
Sbjct: 126 QLAEMQATVRSLGAEKQSANLRAERLEKELQSSSEQNTFLINKLHKAEREINTLSSKVKE 185
Query: 110 XXXXNTRISEQINLEIQRVKLKFQEKLQELAPIPDLLKATQMRLKDA-QQAQAIAEHNAE 168
N I LE R K + + + +L D L++ LK A + + +
Sbjct: 186 LKHSNKLEITDIKLETARAKSELERERNKLQSELDGLQSDNEILKAAVEHHKVLLVEKDR 245
Query: 169 QLARELNCAREKVVHIFRYLYSLYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVL---- 224
+L R++ A+E+ L L L + + KDQ L
Sbjct: 246 ELIRKVQAAKEEGYQKLVVLQDEKLELENRLADLEKMKVEHDVWRQSEKDQYEEKLRASQ 305
Query: 225 LHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNISLKSEIERLKASV--IRTEESALA 282
+ + E R ++Q+ + + EN+ LK +I L+ V + E+ L
Sbjct: 306 MAEEITRKELQSVRLKLQQQIVTIENAEKEKNENS-DLKQQISSLQIQVTSLAQSENDLL 364
Query: 283 NEKRLQEKM-----HECAQLGGELDRTRDEASRALQRAHEQTETVRKCLQTTVAELERQL 337
N ++ ++M EC + ++ + EA + L+ Q + L + + E +
Sbjct: 365 NSNQMLKEMVERLKQECRNFRSQAEKAQLEAEKTLEEKQIQWLEEKHKLHDRITDREEKY 424
Query: 338 AASRAQVSTAEKEREELKNRLHWQMKRLTENFEQAQLRILGLQTQVQS 385
++ ++ A +++ K+ ++KRL E E + + L+T+++S
Sbjct: 425 NQAKEKLQRAAIAQKKRKSLHENKLKRLQEKVEVLEAKKEELETEIRS 472
Score = 39.5 bits (88), Expect = 0.021
Identities = 39/139 (28%), Positives = 63/139 (45%), Gaps = 7/139 (5%)
Query: 253 SQLAENNISLKSEIERLKASVIRT-EESALANEK---RLQEKMHECAQLGGELDRTRDEA 308
++L + LKSE E K R +E + E RL+E E +D T+D +
Sbjct: 20 NKLRYEHTFLKSEFEHQKEEYARILDEGKIKYESEIARLEEDKEELRNQLLNVDLTKD-S 78
Query: 309 SRALQRAHEQTETVRKC--LQTTVAELERQLAASRAQVSTAEKEREELKNRLHWQMKRLT 366
R Q A E+ +K L+ VAEL+ + S AQV A++ + + ++ L
Sbjct: 79 KRVEQLAREKVYLCQKLKGLEAEVAELKAEKENSEAQVENAQRIQVRQLAEMQATVRSLG 138
Query: 367 ENFEQAQLRILGLQTQVQS 385
+ A LR L+ ++QS
Sbjct: 139 AEKQSANLRAERLEKELQS 157
>AF091711-1|AAD39719.1| 1773|Homo sapiens splice variant AKAP350
protein.
Length = 1773
Score = 43.6 bits (98), Expect = 0.001
Identities = 78/382 (20%), Positives = 147/382 (38%), Gaps = 24/382 (6%)
Query: 17 RCQHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELR 76
R Q E +NKL + +M+ GLA + M +++Q V Q +E EID+L
Sbjct: 91 RLQELEQENKLFKDDMEKLGLAIKESDAMSTQDQ----HVLFGKFAQIIQEKEVEIDQLN 146
Query: 77 TLMKEQNDQLQ---DYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQ 133
+ + QL+ D +V + +L+ + Q + EI+++ +
Sbjct: 147 EQVTKLQQQLKITTDNKV-IEEKNELIRDLETQIECLMSDQECVKRNREEEIEQLNEVIE 205
Query: 134 EKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYL 193
+ QELA I + T M + +H + + E ++V + +
Sbjct: 206 KLQQELANIG---QKTSMNAHSLSEEADSLKHQLDVVIAEKLALEQQVETANEEMTFMKN 262
Query: 194 VTTMTLTQEDLFGQSQSEIGRGNKD-QTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRI 252
V T + + Q + R + + + + NS+ + E ++ L +
Sbjct: 263 VLKETNFKMNQLTQELFSLKRERESVEKIQSIPENSVNVAIDHLSKDKPELEVVLTEDAL 322
Query: 253 SQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRAL 312
L EN KS E K S+I E L E + K E Q ++ +++
Sbjct: 323 KSL-ENQTYFKSFEENGKGSIINLETRLLQLESTVSAKDLELTQCYKQIKDMQEQGQFET 381
Query: 313 QRAHEQTETVRKCLQTTVAEL---ERQLAASRA--------QVSTAEKEREELKNRLHWQ 361
+ ++ ++K ++ VA + QL A + Q ++E ER ++N +
Sbjct: 382 EMLQKKIVNLQKIVEEKVAAALVSQIQLEAVQEYAKFCQDNQTISSEPERTNIQNLNQLR 441
Query: 362 MKRLTENFEQAQLRILGLQTQV 383
L + LRI L++QV
Sbjct: 442 EDELGSDISALTLRISELESQV 463
>AF006751-1|AAC25977.1| 977|Homo sapiens ES/130 protein.
Length = 977
Score = 43.6 bits (98), Expect = 0.001
Identities = 87/410 (21%), Positives = 159/410 (38%), Gaps = 39/410 (9%)
Query: 17 RCQHRETQNKLRELEMKFEGLATHTNM----LMGSKEQAFEQEVNVRALKQCYREAREEI 72
+ HRE++ L++ + HT L E+A EQ+ + L + + E+
Sbjct: 437 QASHRESEEALQKRLDEVSRELCHTQSSHASLRADAEKAQEQQQQMAELHSKLQSSEAEV 496
Query: 73 DELRTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKF 132
+ + QLQ+ R + QL E R R ++ + Q +
Sbjct: 497 RSKCEELSGLHGQLQEARA---ENSQLTERIRSIEALLEAGQARDAQDVQAS-QAEADQQ 552
Query: 133 QEKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNA--------EQLARELNCAREKVVHI 184
Q +L+EL L+ + L++A + Q + ++ E LA +EK+ +
Sbjct: 553 QTRLKELESQVSGLEKEAIELREAVEQQKVKNNDLREKNWKAMEALATAEQACKEKLHSL 612
Query: 185 FRYLYS----LYLVTTMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNS---LKPPEKPPE 237
+ L L+ T+ S + + N + + L LK P P E
Sbjct: 613 TQAKEESEKQLCLIEAQTMEALLALLPELSVLAQQNYTEWLQDLKEKGPTLLKHPPAPAE 672
Query: 238 RGGDEKQMALLNQRISQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHEC-AQ 296
D L ++ + E +L++E ++ ++ + TE +K ++E+ A+
Sbjct: 673 PSSD------LASKLREAEETQSTLQAECDQYRSILAETEGMLRDLQKSVEEEEQVWRAK 726
Query: 297 LGG---ELDRTR------DEASRALQRAHEQTETVRKCLQTTVAELERQLAASRAQVSTA 347
+G EL ++R +E L+ E ++ VR+ AELE+ +AA+ A+
Sbjct: 727 VGAAEEELQKSRVTVKHLEEIVEKLKGELESSDQVREHTSHLEAELEKHMAAASAECQNY 786
Query: 348 EKEREELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRRTASSTGDGD 397
KE L+ L +L +AQ + L Q L S DGD
Sbjct: 787 AKEVAGLRQLLLESQSQLDAAKSEAQKQSDELALVRQQLSEMKSHVEDGD 836
Score = 40.7 bits (91), Expect = 0.009
Identities = 79/398 (19%), Positives = 149/398 (37%), Gaps = 38/398 (9%)
Query: 17 RCQHRETQNKLRELEMKFE-GLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDEL 75
R ++ + ++R +E E G A + S+ +A +Q+ ++ L+ +E EL
Sbjct: 514 RAENSQLTERIRSIEALLEAGQARDAQDVQASQAEADQQQTRLKELESQVSGLEKEAIEL 573
Query: 76 RTLMKEQNDQLQDYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQEK 135
R +++Q + D R K +A + + + T+ E+ ++ ++ + E
Sbjct: 574 REAVEQQKVKNNDLREKNWKAMEALATAEQACKEKLHSLTQAKEESEKQLCLIEAQTMEA 633
Query: 136 LQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYLVT 195
L LA +P+L Q + Q + L + E + L
Sbjct: 634 L--LALLPELSVLAQQNYTEWLQD---LKEKGPTLLKHPPAPAEPSSDLASKLREAEETQ 688
Query: 196 TMTLTQEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKP--PERGGDEKQMALLNQRIS 253
+ + D + +E +D L S++ E+ + G E+++ +
Sbjct: 689 STLQAECDQYRSILAETEGMLRD------LQKSVEEEEQVWRAKVGAAEEELQKSRVTVK 742
Query: 254 QLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTR-------- 305
L E LK E+E T EK + EC E+ R
Sbjct: 743 HLEEIVEKLKGELESSDQVREHTSHLEAELEKHMAAASAECQNYAKEVAGLRQLLLESQS 802
Query: 306 --DEASRALQRAHEQTETVRKCLQTTVAELER-QLA---ASRAQVSTAEKEREELKNRLH 359
D A Q+ ++ VR+ L + +E +A AS + AE++ +LK +L
Sbjct: 803 QLDAAKSEAQKQSDELALVRQQLSEMKSHVEDGDIAGAPASSPEAPPAEQDPVQLKTQLE 862
Query: 360 W----------QMKRLTENFEQAQLRILGLQTQVQSLR 387
W Q ++L FE+AQ LQ +++ LR
Sbjct: 863 WTEAILEDEQTQRQKLMAEFEEAQTSACRLQEELEKLR 900
Score = 34.3 bits (75), Expect = 0.80
Identities = 39/177 (22%), Positives = 79/177 (44%), Gaps = 13/177 (7%)
Query: 242 EKQMALLNQRISQLAENNISLKSEIERLKASVIRTEE--SAL-ANEKRLQEKMHECAQLG 298
+K++ +++ + ++ SL+++ E+ + + E S L ++E ++ K E + L
Sbjct: 448 QKRLDEVSRELCHTQSSHASLRADAEKAQEQQQQMAELHSKLQSSEAEVRSKCEELSGLH 507
Query: 299 GELDRTRDEASRALQRAHE-----QTETVRKC--LQTTVAELERQ---LAASRAQVSTAE 348
G+L R E S+ +R + R +Q + AE ++Q L +QVS E
Sbjct: 508 GQLQEARAENSQLTERIRSIEALLEAGQARDAQDVQASQAEADQQQTRLKELESQVSGLE 567
Query: 349 KEREELKNRLHWQMKRLTENFEQAQLRILGLQTQVQSLRRTASSTGDGDGENQECTC 405
KE EL+ + Q + + E+ + L T Q+ + S E+++ C
Sbjct: 568 KEAIELREAVEQQKVKNNDLREKNWKAMEALATAEQACKEKLHSLTQAKEESEKQLC 624
Score = 31.9 bits (69), Expect = 4.3
Identities = 38/188 (20%), Positives = 80/188 (42%), Gaps = 8/188 (4%)
Query: 201 QEDLFGQSQSEIGRGNKDQTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRISQLAENNI 260
QE L +++ R ++ ++ L ++L E ++A L Q +S++++ +
Sbjct: 351 QEQLENGPNTQLARLQQENSI---LRDALNQATSQVE-SKQNAELAKLRQELSKVSKELV 406
Query: 261 SLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRALQRAHEQTE 320
+ + + E A A EK++ + + L + DE SR L
Sbjct: 407 EKSEAVRQDEQQRKALEAKAAAFEKQVLQLQASHRESEEALQKRLDEVSRELCHTQSSHA 466
Query: 321 TVRKCLQTTVAELERQLAA--SRAQVSTAE-KEREELKNRLHWQMKRLTENFEQAQLRIL 377
++R + E ++Q+A S+ Q S AE + + E + LH Q++ Q RI
Sbjct: 467 SLRADAE-KAQEQQQQMAELHSKLQSSEAEVRSKCEELSGLHGQLQEARAENSQLTERIR 525
Query: 378 GLQTQVQS 385
++ +++
Sbjct: 526 SIEALLEA 533
>AC004013-1|AAB96867.2| 2058|Homo sapiens unknown protein.
Length = 2058
Score = 43.6 bits (98), Expect = 0.001
Identities = 78/382 (20%), Positives = 147/382 (38%), Gaps = 24/382 (6%)
Query: 17 RCQHRETQNKLRELEMKFEGLATHTNMLMGSKEQAFEQEVNVRALKQCYREAREEIDELR 76
R Q E +NKL + +M+ GLA + M +++Q V Q +E EID+L
Sbjct: 453 RLQELEQENKLFKDDMEKLGLAIKESDAMSTQDQ----HVLFGKFAQIIQEKEVEIDQLN 508
Query: 77 TLMKEQNDQLQ---DYRVKYLQAQQLVEEQRRQXXXXXXXNTRISEQINLEIQRVKLKFQ 133
+ + QL+ D +V + +L+ + Q + EI+++ +
Sbjct: 509 EQVTKLQQQLKITTDNKV-IEEKNELIRDLETQIECLMSDQECVKRNREEEIEQLNEVIE 567
Query: 134 EKLQELAPIPDLLKATQMRLKDAQQAQAIAEHNAEQLARELNCAREKVVHIFRYLYSLYL 193
+ QELA I + T M + +H + + E ++V + +
Sbjct: 568 KLQQELANIG---QKTSMNAHSLSEEADSLKHQLDVVIAEKLALEQQVETANEEMTFMKN 624
Query: 194 VTTMTLTQEDLFGQSQSEIGRGNKD-QTVHVLLHNSLKPPEKPPERGGDEKQMALLNQRI 252
V T + + Q + R + + + + NS+ + E ++ L +
Sbjct: 625 VLKETNFKMNQLTQELFSLKRERESVEKIQSIPENSVNVAIDHLSKDKPELEVVLTEDAL 684
Query: 253 SQLAENNISLKSEIERLKASVIRTEESALANEKRLQEKMHECAQLGGELDRTRDEASRAL 312
L EN KS E K S+I E L E + K E Q ++ +++
Sbjct: 685 KSL-ENQTYFKSFEENGKGSIINLETRLLQLESTVSAKDLELTQCYKQIKDMQEQGQFET 743
Query: 313 QRAHEQTETVRKCLQTTVAEL---ERQLAASRA--------QVSTAEKEREELKNRLHWQ 361
+ ++ ++K ++ VA + QL A + Q ++E ER ++N +
Sbjct: 744 EMLQKKIVNLQKIVEEKVAAALVSQIQLEAVQEYAKFCQDNQTISSEPERTNIQNLNQLR 803
Query: 362 MKRLTENFEQAQLRILGLQTQV 383
L + LRI L++QV
Sbjct: 804 EDELGSDISALTLRISELESQV 825
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.314 0.127 0.342
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 47,737,056
Number of Sequences: 224733
Number of extensions: 1816555
Number of successful extensions: 22026
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 394
Number of HSP's successfully gapped in prelim test: 1195
Number of HSP's that attempted gapping in prelim test: 15330
Number of HSP's gapped (non-prelim): 6248
length of query: 412
length of database: 73,234,838
effective HSP length: 92
effective length of query: 320
effective length of database: 52,559,402
effective search space: 16819008640
effective search space used: 16819008640
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.6 bits)
S2: 66 (30.7 bits)
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