Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA002041-TA|BGIBMGA002041-PA|IPR000595|Cyclic
nucleotide-binding
(161 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
S42457-1|AAB22778.1| 686|Homo sapiens rod photoreceptor cGMP-ga... 55 1e-07
BC096300-1|AAH96300.1| 694|Homo sapiens cyclic nucleotide gated... 55 1e-07
BC096299-1|AAH96299.1| 676|Homo sapiens cyclic nucleotide gated... 55 1e-07
BC096298-1|AAH96298.1| 694|Homo sapiens cyclic nucleotide gated... 55 1e-07
AK131300-1|BAD18468.1| 698|Homo sapiens mRNA. protein. 55 1e-07
AF065314-1|AAC17440.1| 694|Homo sapiens cone photoreceptor cGMP... 55 1e-07
AC107068-3|AAY40919.1| 690|Homo sapiens unknown protein. 55 1e-07
AC092675-2|AAY24181.1| 694|Homo sapiens unknown protein. 55 1e-07
S76069-1|AAD14208.1| 261|Homo sapiens CNG3 protein. 54 2e-07
S76062-1|AAD14206.1| 261|Homo sapiens CNG1 protein. 54 2e-07
M84741-1|AAA52010.1| 690|Homo sapiens cGMP-gated cation channel... 51 2e-06
AF272900-1|AAF86274.1| 809|Homo sapiens cone photoreceptor cycl... 48 1e-05
BC028024-1|AAH28024.2| 450|Homo sapiens HCN3 protein protein. 46 8e-05
BC000066-1|AAH00066.1| 571|Homo sapiens Unknown (protein for IM... 46 8e-05
AL713999-31|CAI95100.1| 774|Homo sapiens hyperpolarization acti... 46 8e-05
AF488550-1|AAO49470.1| 774|Homo sapiens hyperpolarization activ... 46 8e-05
AB040968-1|BAA96059.2| 711|Homo sapiens KIAA1535 protein protein. 46 8e-05
M65066-1|AAC37564.1| 380|Homo sapiens cAMP-dependent protein ki... 45 1e-04
BC036828-1|AAH36828.2| 381|Homo sapiens protein kinase, cAMP-de... 45 1e-04
BC026734-1|AAH26734.1| 381|Homo sapiens PRKAR1B protein protein. 45 1e-04
U58837-1|AAB63387.1| 1251|Homo sapiens cGMP-gated cation channel... 43 4e-04
L15297-1|AAA65619.1| 623|Homo sapiens cyclic nucleotide-gated c... 43 4e-04
L15296-1|AAA65620.1| 909|Homo sapiens cyclic nucleotide-gated c... 43 4e-04
AF042498-1|AAC04830.1| 1245|Homo sapiens rod photoreceptor CNG-c... 43 4e-04
X14968-1|CAA33094.1| 404|Homo sapiens protein ( Human testis mR... 42 0.001
AJ238850-1|CAB52754.1| 1203|Homo sapiens hyperpolarization-activ... 42 0.001
AJ132429-1|CAB42604.1| 1203|Homo sapiens hyperpolarization-activ... 42 0.001
M33336-1|AAB50921.1| 381|Homo sapiens cAMP-dependent protein ki... 41 0.002
M18468-1|AAB50922.1| 381|Homo sapiens cAMP-dependent protein ki... 41 0.002
BC093042-1|AAH93042.1| 381|Homo sapiens protein kinase, cAMP-de... 41 0.002
BC036285-1|AAH36285.1| 381|Homo sapiens protein kinase, cAMP-de... 41 0.002
L03357-1|AAA60266.1| 593|Homo sapiens RET tyrosine kinase/cAMP ... 40 0.005
AF064876-1|AAC39759.1| 749|Homo sapiens ion channel BCNG-1 prot... 40 0.005
AF228520-1|AAF80179.1| 610|Homo sapiens cone photoreceptor cGMP... 39 0.007
AF488549-1|AAO49469.1| 890|Homo sapiens hyperpolarization activ... 39 0.009
Z92868-1|CAB07437.1| 686|Homo sapiens cGMP-dependent protein ki... 38 0.012
Z92867-1|CAB07436.1| 671|Homo sapiens cGMP-dependent protein ki... 38 0.012
Y07512-1|CAA68810.1| 686|Homo sapiens protein ( Human mRNA for ... 38 0.012
D45864-1|BAA08297.1| 671|Homo sapiens cGMP-dependent protein ki... 38 0.012
BC127090-1|AAI27091.1| 686|Homo sapiens protein kinase, cGMP-de... 38 0.012
AL928686-2|CAI40743.1| 686|Homo sapiens protein kinase, cGMP-de... 38 0.012
AL928686-1|CAI40742.1| 659|Homo sapiens protein kinase, cGMP-de... 38 0.012
AL731537-3|CAI17115.1| 686|Homo sapiens protein kinase, cGMP-de... 38 0.012
AL731537-2|CAI17114.1| 659|Homo sapiens protein kinase, cGMP-de... 38 0.012
AL391378-2|CAI39626.1| 686|Homo sapiens protein kinase, cGMP-de... 38 0.012
AL391378-1|CAI39625.1| 659|Homo sapiens protein kinase, cGMP-de... 38 0.012
AL157399-2|CAI41305.1| 686|Homo sapiens protein kinase, cGMP-de... 38 0.012
AL157399-1|CAI41304.1| 659|Homo sapiens protein kinase, cGMP-de... 38 0.012
AJ133727-1|CAB42630.1| 889|Homo sapiens hyperpolarization-activ... 38 0.012
AJ012582-1|CAB42602.1| 889|Homo sapiens hyperpolarization-activ... 38 0.012
AF065164-1|AAC28444.2| 889|Homo sapiens hyperpolarization-activ... 38 0.012
AF064877-1|AAC39760.1| 597|Homo sapiens ion channel BCNG-2 prot... 38 0.012
BC075800-1|AAH75800.1| 418|Homo sapiens protein kinase, cAMP-de... 36 0.049
Y16106-1|CAA76073.1| 734|Homo sapiens cGMP-dependant protein ki... 35 0.15
X94612-1|CAA64318.1| 762|Homo sapiens Type II cGMP-dependent pr... 35 0.15
D70899-1|BAA18934.1| 762|Homo sapiens cGMP-dependent protein ki... 35 0.15
M31158-1|AAA60099.1| 418|Homo sapiens cAMP-dependent protein ki... 34 0.20
BT007225-1|AAP35889.1| 382|Homo sapiens protein kinase, cAMP-de... 33 0.46
BC002763-1|AAH02763.1| 382|Homo sapiens PRKAR2A protein protein. 33 0.46
U78516-1|AAD03422.1| 1011|Homo sapiens cAMP-regulated guanine nu... 31 2.4
BC040183-1|AAH40183.1| 867|Homo sapiens RAPGEF4 protein protein. 31 2.4
BC024004-1|AAH24004.1| 1011|Homo sapiens Rap guanine nucleotide ... 31 2.4
AB209681-1|BAD92918.1| 643|Homo sapiens RAP guanine-nucleotide-... 31 2.4
AB027471-1|BAB72179.1| 1011|Homo sapiens cAMP-GEFII protein. 31 2.4
Y10807-1|CAA71765.1| 343|Homo sapiens arginine methyltransferas... 30 3.2
Y10806-1|CAA71764.1| 361|Homo sapiens arginine methyltransferas... 30 3.2
Y10805-1|CAA71763.1| 347|Homo sapiens arginine methyltransferas... 30 3.2
CR407608-1|CAG28536.1| 347|Homo sapiens HRMT1L2 protein. 30 3.2
BC109283-1|AAI09284.2| 343|Homo sapiens protein arginine methyl... 30 3.2
BC109282-1|AAI09283.2| 343|Homo sapiens protein arginine methyl... 30 3.2
BC019268-1|AAH19268.2| 352|Homo sapiens PRMT1 protein protein. 30 3.2
AY775289-1|AAV41837.1| 327|Homo sapiens protein arginine methyl... 30 3.2
AF222689-3|AAF62894.1| 347|Homo sapiens protein arginine N-meth... 30 3.2
AF222689-2|AAF62895.1| 343|Homo sapiens protein arginine N-meth... 30 3.2
AF222689-1|AAF62893.1| 361|Homo sapiens protein arginine N-meth... 30 3.2
AC004492-1|AAC08318.1| 112|Homo sapiens CAMP-DEPENDENT PROTEIN ... 29 7.5
BC092404-1|AAH92404.1| 881|Homo sapiens Rap guanine nucleotide ... 29 9.9
BC068477-1|AAH68477.1| 343|Homo sapiens RAPGEF3 protein protein. 29 9.9
BC062688-1|AAH62688.1| 312|Homo sapiens PRKG1 protein protein. 29 9.9
BC017728-1|AAH17728.1| 881|Homo sapiens Rap guanine nucleotide ... 29 9.9
AL391378-3|CAI39627.1| 181|Homo sapiens protein kinase, cGMP-de... 29 9.9
AL157399-3|CAI41306.1| 181|Homo sapiens protein kinase, cGMP-de... 29 9.9
AF103905-1|AAC83381.1| 881|Homo sapiens Rap1 guanine-nucleotide... 29 9.9
>S42457-1|AAB22778.1| 686|Homo sapiens rod photoreceptor cGMP-gated
channel protein.
Length = 686
Score = 54.8 bits (126), Expect = 1e-07
Identities = 35/123 (28%), Positives = 65/123 (52%), Gaps = 8/123 (6%)
Query: 14 LPDILQREIMLSCYRGYIMRIPYFCDWAVSVIEDIVVMLKEKIYLANDIVAEPWIQGDGL 73
LPD L+ EI ++ + + ++ F D ++ ++V+ L+ ++Y D + + G +
Sbjct: 453 LPDKLRAEIAINVHLDTLKKVRIFADCEAGLLVELVLKLQPQVYSPGDYICKKGDIGREM 512
Query: 74 IIVDAGELAVYSVDDEETAHLI--DGDYFGELSLITDK-----EVRTSYVVTITDSQILT 126
I+ G+LAV + DD T ++ DG YFGE+S++ K RT+ + +I S +
Sbjct: 513 YIIKEGKLAVVA-DDGVTQFVVLSDGSYFGEISILNIKGSKAGNRRTANIKSIGYSDLFC 571
Query: 127 LDK 129
L K
Sbjct: 572 LSK 574
>BC096300-1|AAH96300.1| 694|Homo sapiens cyclic nucleotide gated
channel alpha 3 protein.
Length = 694
Score = 54.8 bits (126), Expect = 1e-07
Identities = 35/125 (28%), Positives = 67/125 (53%), Gaps = 8/125 (6%)
Query: 12 RSLPDILQREIMLSCYRGYIMRIPYFCDWAVSVIEDIVVMLKEKIYLANDIVAEPWIQGD 71
+SLPD L+ EI ++ + + ++ F D ++ ++V+ L+ ++ D + + G
Sbjct: 458 KSLPDKLKAEIAINVHLDTLKKVRIFQDCEAGLLVELVLKLRPTVFSPGDYICKKGDIGK 517
Query: 72 GLIIVDAGELAVYSVDDEETAHLI--DGDYFGELSLITDK-----EVRTSYVVTITDSQI 124
+ I++ G+LAV + DD T ++ DG YFGE+S++ K RT+ + +I S +
Sbjct: 518 EMYIINEGKLAVVA-DDGVTQFVVLSDGSYFGEISILNIKGSKSGNRRTANIRSIGYSDL 576
Query: 125 LTLDK 129
L K
Sbjct: 577 FCLSK 581
>BC096299-1|AAH96299.1| 676|Homo sapiens cyclic nucleotide gated
channel alpha 3 protein.
Length = 676
Score = 54.8 bits (126), Expect = 1e-07
Identities = 35/125 (28%), Positives = 67/125 (53%), Gaps = 8/125 (6%)
Query: 12 RSLPDILQREIMLSCYRGYIMRIPYFCDWAVSVIEDIVVMLKEKIYLANDIVAEPWIQGD 71
+SLPD L+ EI ++ + + ++ F D ++ ++V+ L+ ++ D + + G
Sbjct: 440 KSLPDKLKAEIAINVHLDTLKKVRIFQDCEAGLLVELVLKLRPTVFSPGDYICKKGDIGK 499
Query: 72 GLIIVDAGELAVYSVDDEETAHLI--DGDYFGELSLITDK-----EVRTSYVVTITDSQI 124
+ I++ G+LAV + DD T ++ DG YFGE+S++ K RT+ + +I S +
Sbjct: 500 EMYIINEGKLAVVA-DDGVTQFVVLSDGSYFGEISILNIKGSKSGNRRTANIRSIGYSDL 558
Query: 125 LTLDK 129
L K
Sbjct: 559 FCLSK 563
>BC096298-1|AAH96298.1| 694|Homo sapiens cyclic nucleotide gated
channel alpha 3 protein.
Length = 694
Score = 54.8 bits (126), Expect = 1e-07
Identities = 35/125 (28%), Positives = 67/125 (53%), Gaps = 8/125 (6%)
Query: 12 RSLPDILQREIMLSCYRGYIMRIPYFCDWAVSVIEDIVVMLKEKIYLANDIVAEPWIQGD 71
+SLPD L+ EI ++ + + ++ F D ++ ++V+ L+ ++ D + + G
Sbjct: 458 KSLPDKLKAEIAINVHLDTLKKVRIFQDCEAGLLVELVLKLRPTVFSPGDYICKKGDIGK 517
Query: 72 GLIIVDAGELAVYSVDDEETAHLI--DGDYFGELSLITDK-----EVRTSYVVTITDSQI 124
+ I++ G+LAV + DD T ++ DG YFGE+S++ K RT+ + +I S +
Sbjct: 518 EMYIINEGKLAVVA-DDGVTQFVVLSDGSYFGEISILNIKGSKSGNRRTANIRSIGYSDL 576
Query: 125 LTLDK 129
L K
Sbjct: 577 FCLSK 581
>AK131300-1|BAD18468.1| 698|Homo sapiens mRNA. protein.
Length = 698
Score = 54.8 bits (126), Expect = 1e-07
Identities = 35/125 (28%), Positives = 67/125 (53%), Gaps = 8/125 (6%)
Query: 12 RSLPDILQREIMLSCYRGYIMRIPYFCDWAVSVIEDIVVMLKEKIYLANDIVAEPWIQGD 71
+SLPD L+ EI ++ + + ++ F D ++ ++V+ L+ ++ D + + G
Sbjct: 462 KSLPDKLKAEIAINVHLDTLKKVRIFQDCEAGLLVELVLKLRPTVFSPGDYICKKGDIGK 521
Query: 72 GLIIVDAGELAVYSVDDEETAHLI--DGDYFGELSLITDK-----EVRTSYVVTITDSQI 124
+ I++ G+LAV + DD T ++ DG YFGE+S++ K RT+ + +I S +
Sbjct: 522 EMYIINEGKLAVVA-DDGVTQFVVLSDGSYFGEISILNIKGSKSGNRRTANIRSIGYSDL 580
Query: 125 LTLDK 129
L K
Sbjct: 581 FCLSK 585
>AF065314-1|AAC17440.1| 694|Homo sapiens cone photoreceptor
cGMP-gated channel alpha subunit protein.
Length = 694
Score = 54.8 bits (126), Expect = 1e-07
Identities = 35/125 (28%), Positives = 67/125 (53%), Gaps = 8/125 (6%)
Query: 12 RSLPDILQREIMLSCYRGYIMRIPYFCDWAVSVIEDIVVMLKEKIYLANDIVAEPWIQGD 71
+SLPD L+ EI ++ + + ++ F D ++ ++V+ L+ ++ D + + G
Sbjct: 458 KSLPDKLKAEIAINVHLDTLKKVRIFQDCEAGLLVELVLKLRPTVFSPGDYICKKGDIGK 517
Query: 72 GLIIVDAGELAVYSVDDEETAHLI--DGDYFGELSLITDK-----EVRTSYVVTITDSQI 124
+ I++ G+LAV + DD T ++ DG YFGE+S++ K RT+ + +I S +
Sbjct: 518 EMYIINEGKLAVVA-DDGVTQFVVLSDGSYFGEISILNIKGSKSGNRRTANIRSIGYSDL 576
Query: 125 LTLDK 129
L K
Sbjct: 577 FCLSK 581
>AC107068-3|AAY40919.1| 690|Homo sapiens unknown protein.
Length = 690
Score = 54.8 bits (126), Expect = 1e-07
Identities = 35/123 (28%), Positives = 65/123 (52%), Gaps = 8/123 (6%)
Query: 14 LPDILQREIMLSCYRGYIMRIPYFCDWAVSVIEDIVVMLKEKIYLANDIVAEPWIQGDGL 73
LPD L+ EI ++ + + ++ F D ++ ++V+ L+ ++Y D + + G +
Sbjct: 457 LPDKLRAEIAINVHLDTLKKVRIFADCEAGLLVELVLKLQPQVYSPGDYICKKGDIGREM 516
Query: 74 IIVDAGELAVYSVDDEETAHLI--DGDYFGELSLITDK-----EVRTSYVVTITDSQILT 126
I+ G+LAV + DD T ++ DG YFGE+S++ K RT+ + +I S +
Sbjct: 517 YIIKEGKLAVVA-DDGVTQFVVLSDGSYFGEISILNIKGSKAGNRRTANIKSIGYSDLFC 575
Query: 127 LDK 129
L K
Sbjct: 576 LSK 578
>AC092675-2|AAY24181.1| 694|Homo sapiens unknown protein.
Length = 694
Score = 54.8 bits (126), Expect = 1e-07
Identities = 35/125 (28%), Positives = 67/125 (53%), Gaps = 8/125 (6%)
Query: 12 RSLPDILQREIMLSCYRGYIMRIPYFCDWAVSVIEDIVVMLKEKIYLANDIVAEPWIQGD 71
+SLPD L+ EI ++ + + ++ F D ++ ++V+ L+ ++ D + + G
Sbjct: 458 KSLPDKLKAEIAINVHLDTLKKVRIFQDCEAGLLVELVLKLRPTVFSPGDYICKKGDIGK 517
Query: 72 GLIIVDAGELAVYSVDDEETAHLI--DGDYFGELSLITDK-----EVRTSYVVTITDSQI 124
+ I++ G+LAV + DD T ++ DG YFGE+S++ K RT+ + +I S +
Sbjct: 518 EMYIINEGKLAVVA-DDGVTQFVVLSDGSYFGEISILNIKGSKSGNRRTANIRSIGYSDL 576
Query: 125 LTLDK 129
L K
Sbjct: 577 FCLSK 581
>S76069-1|AAD14208.1| 261|Homo sapiens CNG3 protein.
Length = 261
Score = 54.4 bits (125), Expect = 2e-07
Identities = 29/100 (29%), Positives = 57/100 (57%), Gaps = 3/100 (3%)
Query: 12 RSLPDILQREIMLSCYRGYIMRIPYFCDWAVSVIEDIVVMLKEKIYLANDIVAEPWIQGD 71
+SLPD L+ EI ++ + + ++ F D ++ ++V+ L+ ++ D + + G
Sbjct: 139 KSLPDKLKAEIAINVHLDTLKKVRIFQDCEAGLLVELVLKLRPTVFSPGDYICKKGDIGK 198
Query: 72 GLIIVDAGELAVYSVDDEETAHLI--DGDYFGELSLITDK 109
+ I++ G+LAV + DD T ++ DG YFGE+S++ K
Sbjct: 199 EMYIINEGKLAVVA-DDGVTQFVVLSDGSYFGEISILNIK 237
>S76062-1|AAD14206.1| 261|Homo sapiens CNG1 protein.
Length = 261
Score = 54.0 bits (124), Expect = 2e-07
Identities = 29/98 (29%), Positives = 55/98 (56%), Gaps = 3/98 (3%)
Query: 14 LPDILQREIMLSCYRGYIMRIPYFCDWAVSVIEDIVVMLKEKIYLANDIVAEPWIQGDGL 73
LPD L+ EI ++ + + ++ F D ++ ++V+ L+ ++Y D + + G +
Sbjct: 141 LPDKLRAEIAINVHLDTLKKVRIFADCEAGLLVELVLKLQPQVYSPGDYICKKGDIGREM 200
Query: 74 IIVDAGELAVYSVDDEETAHLI--DGDYFGELSLITDK 109
I+ G+LAV + DD T ++ DG YFGE+S++ K
Sbjct: 201 YIIKEGKLAVVA-DDGVTQFVVLSDGSYFGEISILNIK 237
>M84741-1|AAA52010.1| 690|Homo sapiens cGMP-gated cation channel
protein protein.
Length = 690
Score = 51.2 bits (117), Expect = 2e-06
Identities = 34/123 (27%), Positives = 64/123 (52%), Gaps = 8/123 (6%)
Query: 14 LPDILQREIMLSCYRGYIMRIPYFCDWAVSVIEDIVVMLKEKIYLANDIVAEPWIQGDGL 73
LPD L+ EI ++ + + ++ F D ++ ++V+ L+ ++Y D + + G +
Sbjct: 457 LPDKLRAEIAINVHLDTLKKVRIFADCEAGLLVELVLKLQPQVYSPGDYICKKGDIGREM 516
Query: 74 IIVDAGELAVYSVDDEETAHLI--DGDYFGELSLITDK-----EVRTSYVVTITDSQILT 126
I+ G+LAV + DD T ++ DG FGE+S++ K RT+ + +I S +
Sbjct: 517 YIIKEGKLAVVA-DDGVTQFVVLSDGSTFGEISILNIKGSKAGNRRTANIKSIGYSDLFC 575
Query: 127 LDK 129
L K
Sbjct: 576 LSK 578
>AF272900-1|AAF86274.1| 809|Homo sapiens cone photoreceptor cyclic
nucleotide-gated channel beta subunit protein.
Length = 809
Score = 48.4 bits (110), Expect = 1e-05
Identities = 37/136 (27%), Positives = 63/136 (46%), Gaps = 4/136 (2%)
Query: 10 LYRSLPDILQREIMLSCYRGYIMRIPYFCDWAVSVIEDIVVMLKEKIYLANDIVAEPWIQ 69
L ++LP +Q + + I ++ F +I D+++ LK +YL D V +
Sbjct: 498 LLKTLPTTVQLALAIDVNFSIISKVDLFKGCDTQMIYDMLLRLKSVLYLPGDFVCKKGEI 557
Query: 70 GDGLIIVDAGELAVYSVDD--EETAHLIDGDYFGELSLIT--DKEVRTSYVVTITDSQIL 125
G + I+ GE+ V D + L G FGE+SL+ RT+ VV + +L
Sbjct: 558 GKEMYIIKHGEVQVLGGPDGTKVLVTLKAGSVFGEISLLAAGGGNRRTANVVAHGFANLL 617
Query: 126 TLDKGAFRMYMRNHTD 141
TLDK + + ++ D
Sbjct: 618 TLDKKTLQEILVHYPD 633
>BC028024-1|AAH28024.2| 450|Homo sapiens HCN3 protein protein.
Length = 450
Score = 45.6 bits (103), Expect = 8e-05
Identities = 32/119 (26%), Positives = 57/119 (47%), Gaps = 2/119 (1%)
Query: 14 LPDILQREIMLSCYRGYIMRIPYFCDWAVSVIEDIVVMLKEKIYLANDIVAEPWIQGDGL 73
L + L+ EI+ RG + +P F S + ++ L+ +++ D+V G +
Sbjct: 82 LSEPLREEIINFTCRGLVAHMPLFAHADPSFVTAVLTKLRFEVFQPGDLVVREGSVGRKM 141
Query: 74 IIVDAGELAVYSVDDEETAHLIDGDYFGELSLITDKEVRTSYVVTITDSQILTLDKGAF 132
+ G L+V + +T L DG YFGE+ L+T + RT+ V T ++ +L F
Sbjct: 142 YFIQHGLLSVLARGARDT-RLTDGSYFGEICLLT-RGRRTASVRADTYCRLYSLSVDHF 198
>BC000066-1|AAH00066.1| 571|Homo sapiens Unknown (protein for
IMAGE:3507934) protein.
Length = 571
Score = 45.6 bits (103), Expect = 8e-05
Identities = 32/119 (26%), Positives = 57/119 (47%), Gaps = 2/119 (1%)
Query: 14 LPDILQREIMLSCYRGYIMRIPYFCDWAVSVIEDIVVMLKEKIYLANDIVAEPWIQGDGL 73
L + L+ EI+ RG + +P F S + ++ L+ +++ D+V G +
Sbjct: 203 LSEPLREEIINFTCRGLVAHMPLFAHADPSFVTAVLTKLRFEVFQPGDLVVREGSVGRKM 262
Query: 74 IIVDAGELAVYSVDDEETAHLIDGDYFGELSLITDKEVRTSYVVTITDSQILTLDKGAF 132
+ G L+V + +T L DG YFGE+ L+T + RT+ V T ++ +L F
Sbjct: 263 YFIQHGLLSVLARGARDT-RLTDGSYFGEICLLT-RGRRTASVRADTYCRLYSLSVDHF 319
>AL713999-31|CAI95100.1| 774|Homo sapiens hyperpolarization
activated cyclic nucleotide-gated potassium channel 3
protein.
Length = 774
Score = 45.6 bits (103), Expect = 8e-05
Identities = 32/119 (26%), Positives = 57/119 (47%), Gaps = 2/119 (1%)
Query: 14 LPDILQREIMLSCYRGYIMRIPYFCDWAVSVIEDIVVMLKEKIYLANDIVAEPWIQGDGL 73
L + L+ EI+ RG + +P F S + ++ L+ +++ D+V G +
Sbjct: 406 LSEPLREEIINFTCRGLVAHMPLFAHADPSFVTAVLTKLRFEVFQPGDLVVREGSVGRKM 465
Query: 74 IIVDAGELAVYSVDDEETAHLIDGDYFGELSLITDKEVRTSYVVTITDSQILTLDKGAF 132
+ G L+V + +T L DG YFGE+ L+T + RT+ V T ++ +L F
Sbjct: 466 YFIQHGLLSVLARGARDT-RLTDGSYFGEICLLT-RGRRTASVRADTYCRLYSLSVDHF 522
>AF488550-1|AAO49470.1| 774|Homo sapiens hyperpolarization
activated cyclic nucleotide-gated potassium channel
protein.
Length = 774
Score = 45.6 bits (103), Expect = 8e-05
Identities = 32/119 (26%), Positives = 57/119 (47%), Gaps = 2/119 (1%)
Query: 14 LPDILQREIMLSCYRGYIMRIPYFCDWAVSVIEDIVVMLKEKIYLANDIVAEPWIQGDGL 73
L + L+ EI+ RG + +P F S + ++ L+ +++ D+V G +
Sbjct: 406 LSEPLREEIINFTCRGLVAHMPLFAHADPSFVTAVLTKLRFEVFQPGDLVVREGSVGRKM 465
Query: 74 IIVDAGELAVYSVDDEETAHLIDGDYFGELSLITDKEVRTSYVVTITDSQILTLDKGAF 132
+ G L+V + +T L DG YFGE+ L+T + RT+ V T ++ +L F
Sbjct: 466 YFIQHGLLSVLARGARDT-RLTDGSYFGEICLLT-RGRRTASVRADTYCRLYSLSVDHF 522
>AB040968-1|BAA96059.2| 711|Homo sapiens KIAA1535 protein protein.
Length = 711
Score = 45.6 bits (103), Expect = 8e-05
Identities = 32/119 (26%), Positives = 57/119 (47%), Gaps = 2/119 (1%)
Query: 14 LPDILQREIMLSCYRGYIMRIPYFCDWAVSVIEDIVVMLKEKIYLANDIVAEPWIQGDGL 73
L + L+ EI+ RG + +P F S + ++ L+ +++ D+V G +
Sbjct: 343 LSEPLREEIINFTCRGLVAHMPLFAHADPSFVTAVLTKLRFEVFQPGDLVVREGSVGRKM 402
Query: 74 IIVDAGELAVYSVDDEETAHLIDGDYFGELSLITDKEVRTSYVVTITDSQILTLDKGAF 132
+ G L+V + +T L DG YFGE+ L+T + RT+ V T ++ +L F
Sbjct: 403 YFIQHGLLSVLARGARDT-RLTDGSYFGEICLLT-RGRRTASVRADTYCRLYSLSVDHF 459
>M65066-1|AAC37564.1| 380|Homo sapiens cAMP-dependent protein
kinase RI-beta regulatory subunit protein.
Length = 380
Score = 44.8 bits (101), Expect = 1e-04
Identities = 26/84 (30%), Positives = 46/84 (54%), Gaps = 2/84 (2%)
Query: 57 YLANDIVAEPWIQGDGLIIVDAGELAVYSVDDEETAHLIDGDYFGELSLITDKEVRTSYV 116
++A + V + +GD +VD GE+ VY V+ E ++ +G FGEL+LI R + V
Sbjct: 157 HIAGETVIQQGNEGDNFYVVDQGEVDVY-VNGEWVTNISEGGSFGELALIYGTP-RAATV 214
Query: 117 VTITDSQILTLDKGAFRMYMRNHT 140
TD ++ +D+ ++R + T
Sbjct: 215 KAKTDLKLWGIDRDSYRRILMGST 238
>BC036828-1|AAH36828.2| 381|Homo sapiens protein kinase,
cAMP-dependent, regulatory, type I, beta protein.
Length = 381
Score = 44.8 bits (101), Expect = 1e-04
Identities = 26/84 (30%), Positives = 46/84 (54%), Gaps = 2/84 (2%)
Query: 57 YLANDIVAEPWIQGDGLIIVDAGELAVYSVDDEETAHLIDGDYFGELSLITDKEVRTSYV 116
++A + V + +GD +VD GE+ VY V+ E ++ +G FGEL+LI R + V
Sbjct: 158 HIAGETVIQQGNEGDNFYVVDQGEVDVY-VNGEWVTNISEGGSFGELALIYGTP-RAATV 215
Query: 117 VTITDSQILTLDKGAFRMYMRNHT 140
TD ++ +D+ ++R + T
Sbjct: 216 KAKTDLKLWGIDRDSYRRILMGST 239
>BC026734-1|AAH26734.1| 381|Homo sapiens PRKAR1B protein protein.
Length = 381
Score = 44.8 bits (101), Expect = 1e-04
Identities = 26/84 (30%), Positives = 46/84 (54%), Gaps = 2/84 (2%)
Query: 57 YLANDIVAEPWIQGDGLIIVDAGELAVYSVDDEETAHLIDGDYFGELSLITDKEVRTSYV 116
++A + V + +GD +VD GE+ VY V+ E ++ +G FGEL+LI R + V
Sbjct: 158 HIAGETVIQQGNEGDNFYVVDQGEVDVY-VNGEWVTNISEGGSFGELALIYGTP-RAATV 215
Query: 117 VTITDSQILTLDKGAFRMYMRNHT 140
TD ++ +D+ ++R + T
Sbjct: 216 KAKTDLKLWGIDRDSYRRILMGST 239
>U58837-1|AAB63387.1| 1251|Homo sapiens cGMP-gated cation channel beta
subunit protein.
Length = 1251
Score = 43.2 bits (97), Expect = 4e-04
Identities = 32/120 (26%), Positives = 57/120 (47%), Gaps = 4/120 (3%)
Query: 14 LPDILQREIMLSCYRGYIMRIPYFCDWAVSVIEDIVVMLKEKIYLANDIVAEPWIQGDGL 73
LPD ++ ++ + + ++ F +I D++ L+ +YL ND V + G +
Sbjct: 940 LPDKMRLDLAIDVNYNIVSKVALFQGCDRQMIFDMLKRLRSVVYLPNDYVCKKGEIGREM 999
Query: 74 IIVDAGELAVYSVDDEET--AHLIDGDYFGELSLIT--DKEVRTSYVVTITDSQILTLDK 129
I+ AG++ V D ++ L G FGE+SL+ RT+ VV + + LDK
Sbjct: 1000 YIIQAGQVQVLGGPDGKSVLVTLKAGSVFGEISLLAVGGGNRRTANVVAHGFTNLFILDK 1059
>L15297-1|AAA65619.1| 623|Homo sapiens cyclic nucleotide-gated
cation channel protein.
Length = 623
Score = 43.2 bits (97), Expect = 4e-04
Identities = 32/120 (26%), Positives = 57/120 (47%), Gaps = 4/120 (3%)
Query: 14 LPDILQREIMLSCYRGYIMRIPYFCDWAVSVIEDIVVMLKEKIYLANDIVAEPWIQGDGL 73
LPD ++ ++ + + ++ F +I D++ L+ +YL ND V + G +
Sbjct: 312 LPDKMRLDLAIDVNYNIVSKVALFQGCDRQMIFDMLKRLRSVVYLPNDYVCKKGEIGREM 371
Query: 74 IIVDAGELAVYSVDDEET--AHLIDGDYFGELSLIT--DKEVRTSYVVTITDSQILTLDK 129
I+ AG++ V D ++ L G FGE+SL+ RT+ VV + + LDK
Sbjct: 372 YIIQAGQVQVLGGPDGKSVLVTLKAGSVFGEISLLAVGGGNRRTANVVAHGFTNLFILDK 431
>L15296-1|AAA65620.1| 909|Homo sapiens cyclic nucleotide-gated
cation channel protein.
Length = 909
Score = 43.2 bits (97), Expect = 4e-04
Identities = 32/120 (26%), Positives = 57/120 (47%), Gaps = 4/120 (3%)
Query: 14 LPDILQREIMLSCYRGYIMRIPYFCDWAVSVIEDIVVMLKEKIYLANDIVAEPWIQGDGL 73
LPD ++ ++ + + ++ F +I D++ L+ +YL ND V + G +
Sbjct: 598 LPDKMRLDLAIDVNYNIVSKVALFQGCDRQMIFDMLKRLRSVVYLPNDYVCKKGEIGREM 657
Query: 74 IIVDAGELAVYSVDDEET--AHLIDGDYFGELSLIT--DKEVRTSYVVTITDSQILTLDK 129
I+ AG++ V D ++ L G FGE+SL+ RT+ VV + + LDK
Sbjct: 658 YIIQAGQVQVLGGPDGKSVLVTLKAGSVFGEISLLAVGGGNRRTANVVAHGFTNLFILDK 717
>AF042498-1|AAC04830.1| 1245|Homo sapiens rod photoreceptor
CNG-channel beta subunit protein.
Length = 1245
Score = 43.2 bits (97), Expect = 4e-04
Identities = 32/120 (26%), Positives = 57/120 (47%), Gaps = 4/120 (3%)
Query: 14 LPDILQREIMLSCYRGYIMRIPYFCDWAVSVIEDIVVMLKEKIYLANDIVAEPWIQGDGL 73
LPD ++ ++ + + ++ F +I D++ L+ +YL ND V + G +
Sbjct: 934 LPDKMRLDLAIDVNYNIVSKVALFQGCDRQMIFDMLKRLRSVVYLPNDYVCKKGEIGREM 993
Query: 74 IIVDAGELAVYSVDDEET--AHLIDGDYFGELSLIT--DKEVRTSYVVTITDSQILTLDK 129
I+ AG++ V D ++ L G FGE+SL+ RT+ VV + + LDK
Sbjct: 994 YIIQAGQVQVLGGPDGKSVLVTLKAGSVFGEISLLAVGGGNRRTANVVAHGFTNLFILDK 1053
>X14968-1|CAA33094.1| 404|Homo sapiens protein ( Human testis mRNA
for the RII-alpha subunit of cAMP dependent protein
kinase. ).
Length = 404
Score = 41.9 bits (94), Expect = 0.001
Identities = 31/117 (26%), Positives = 53/117 (45%), Gaps = 12/117 (10%)
Query: 27 YRGYIMRIPYFCDWAVSVIEDIVVMLKEKIYLANDIVAEPWIQGDGLIIVDAGELAVY-- 84
+ +I +P VS IV ++ EKIY + + + D I+++GE+++
Sbjct: 252 FESFIESVPLLKSLEVSERMKIVDVIGEKIYKDGERIITQGEKADSFYIIESGEVSILIR 311
Query: 85 ---------SVDDEETAHLIDGDYFGELSLITDKEVRTSYVVTITDSQILTLDKGAF 132
+ E A G YFGEL+L+T+K R + + D + L +D AF
Sbjct: 312 SRTKSNKDGGNQEVEIARCHKGQYFGELALVTNKP-RAASAYAVGDVKCLVMDVQAF 367
Score = 31.9 bits (69), Expect = 1.1
Identities = 21/92 (22%), Positives = 44/92 (47%), Gaps = 4/92 (4%)
Query: 45 IEDIVVMLKEKIYLANDIVAEPWIQGDGLIIVDAGELAVYSVDDEETAHLIDGD---YFG 101
+ ++ + E+I A++ V + GD +++ G + D +T + D FG
Sbjct: 148 LSQVLDAMFERIVKADEHVIDQGDDGDNFYVIERGTYDILVTKDNQTRSVGQYDNRGSFG 207
Query: 102 ELSLITDKEVRTSYVVTITDSQILTLDKGAFR 133
EL+L+ + R + +V ++ + LD+ FR
Sbjct: 208 ELALMYNTP-RAATIVATSEGSLWGLDRVTFR 238
>AJ238850-1|CAB52754.1| 1203|Homo sapiens
hyperpolarization-activated channel type 4 protein.
Length = 1203
Score = 41.5 bits (93), Expect = 0.001
Identities = 29/126 (23%), Positives = 60/126 (47%), Gaps = 2/126 (1%)
Query: 14 LPDILQREIMLSCYRGYIMRIPYFCDWAVSVIEDIVVMLKEKIYLANDIVAEPWIQGDGL 73
L + L+ EI+ R + +P F + + + ++ L+ +++ D + G +
Sbjct: 573 LSEPLREEIINFNCRKLVASMPLFANADPNFVTSMLTKLRFEVFQPGDYIIREGTIGKKM 632
Query: 74 IIVDAGELAVYSVDDEETAHLIDGDYFGELSLITDKEVRTSYVVTITDSQILTLDKGAFR 133
+ G ++V + ++ET L DG YFGE+ L+T + RT+ V T ++ +L F
Sbjct: 633 YFIQHGVVSVLTKGNKETK-LADGSYFGEICLLT-RGRRTASVRADTYCRLYSLSVDNFN 690
Query: 134 MYMRNH 139
+ +
Sbjct: 691 EVLEEY 696
>AJ132429-1|CAB42604.1| 1203|Homo sapiens
hyperpolarization-activated cyclic nucleotide gated
cation channel hHCN4 protein.
Length = 1203
Score = 41.5 bits (93), Expect = 0.001
Identities = 29/126 (23%), Positives = 60/126 (47%), Gaps = 2/126 (1%)
Query: 14 LPDILQREIMLSCYRGYIMRIPYFCDWAVSVIEDIVVMLKEKIYLANDIVAEPWIQGDGL 73
L + L+ EI+ R + +P F + + + ++ L+ +++ D + G +
Sbjct: 573 LSEPLREEIINFNCRKLVASMPLFANADPNFVTSMLTKLRFEVFQPGDYIIREGTIGKKM 632
Query: 74 IIVDAGELAVYSVDDEETAHLIDGDYFGELSLITDKEVRTSYVVTITDSQILTLDKGAFR 133
+ G ++V + ++ET L DG YFGE+ L+T + RT+ V T ++ +L F
Sbjct: 633 YFIQHGVVSVLTKGNKETK-LADGSYFGEICLLT-RGRRTASVRADTYCRLYSLSVDNFN 690
Query: 134 MYMRNH 139
+ +
Sbjct: 691 EVLEEY 696
>M33336-1|AAB50921.1| 381|Homo sapiens cAMP-dependent protein
kinase type I-alpha subunit protein.
Length = 381
Score = 40.7 bits (91), Expect = 0.002
Identities = 24/84 (28%), Positives = 45/84 (53%), Gaps = 2/84 (2%)
Query: 57 YLANDIVAEPWIQGDGLIIVDAGELAVYSVDDEETAHLIDGDYFGELSLITDKEVRTSYV 116
++A + V + +GD ++D GE VY V++E + +G FGEL+LI R + V
Sbjct: 158 FIAGETVIQQGDEGDNFYVIDQGETDVY-VNNEWATSVGEGGSFGELALIYGTP-RAATV 215
Query: 117 VTITDSQILTLDKGAFRMYMRNHT 140
T+ ++ +D+ ++R + T
Sbjct: 216 KAKTNVKLWGIDRDSYRRILMGST 239
>M18468-1|AAB50922.1| 381|Homo sapiens cAMP-dependent protein
kinase regulatory subunit type 1 protein.
Length = 381
Score = 40.7 bits (91), Expect = 0.002
Identities = 24/84 (28%), Positives = 45/84 (53%), Gaps = 2/84 (2%)
Query: 57 YLANDIVAEPWIQGDGLIIVDAGELAVYSVDDEETAHLIDGDYFGELSLITDKEVRTSYV 116
++A + V + +GD ++D GE VY V++E + +G FGEL+LI R + V
Sbjct: 158 FIAGETVIQQGDEGDNFYVIDQGETDVY-VNNEWATSVGEGGSFGELALIYGTP-RAATV 215
Query: 117 VTITDSQILTLDKGAFRMYMRNHT 140
T+ ++ +D+ ++R + T
Sbjct: 216 KAKTNVKLWGIDRDSYRRILMGST 239
>BC093042-1|AAH93042.1| 381|Homo sapiens protein kinase,
cAMP-dependent, regulatory, type I, alpha (tissue
specific exti protein.
Length = 381
Score = 40.7 bits (91), Expect = 0.002
Identities = 24/84 (28%), Positives = 45/84 (53%), Gaps = 2/84 (2%)
Query: 57 YLANDIVAEPWIQGDGLIIVDAGELAVYSVDDEETAHLIDGDYFGELSLITDKEVRTSYV 116
++A + V + +GD ++D GE VY V++E + +G FGEL+LI R + V
Sbjct: 158 FIAGETVIQQGDEGDNFYVIDQGETDVY-VNNEWATSVGEGGSFGELALIYGTP-RAATV 215
Query: 117 VTITDSQILTLDKGAFRMYMRNHT 140
T+ ++ +D+ ++R + T
Sbjct: 216 KAKTNVKLWGIDRDSYRRILMGST 239
>BC036285-1|AAH36285.1| 381|Homo sapiens protein kinase,
cAMP-dependent, regulatory, type I, alpha (tissue
specific exti protein.
Length = 381
Score = 40.7 bits (91), Expect = 0.002
Identities = 24/84 (28%), Positives = 45/84 (53%), Gaps = 2/84 (2%)
Query: 57 YLANDIVAEPWIQGDGLIIVDAGELAVYSVDDEETAHLIDGDYFGELSLITDKEVRTSYV 116
++A + V + +GD ++D GE VY V++E + +G FGEL+LI R + V
Sbjct: 158 FIAGETVIQQGDEGDNFYVIDQGETDVY-VNNEWATSVGEGGSFGELALIYGTP-RAATV 215
Query: 117 VTITDSQILTLDKGAFRMYMRNHT 140
T+ ++ +D+ ++R + T
Sbjct: 216 KAKTNVKLWGIDRDSYRRILMGST 239
>L03357-1|AAA60266.1| 593|Homo sapiens RET tyrosine kinase/cAMP
protein kinase A subunit RI protein.
Length = 593
Score = 39.5 bits (88), Expect = 0.005
Identities = 23/77 (29%), Positives = 43/77 (55%), Gaps = 2/77 (2%)
Query: 57 YLANDIVAEPWIQGDGLIIVDAGELAVYSVDDEETAHLIDGDYFGELSLITDKEVRTSYV 116
++A + V + +GD ++D GE VY V++E + +G FGEL+LI R + V
Sbjct: 158 FIAGETVIQQGDEGDNFYVIDQGETDVY-VNNEWATSVGEGGSFGELALIYGTP-RAATV 215
Query: 117 VTITDSQILTLDKGAFR 133
T+ ++ +D+ ++R
Sbjct: 216 KAKTNVKLWGIDRDSYR 232
>AF064876-1|AAC39759.1| 749|Homo sapiens ion channel BCNG-1
protein.
Length = 749
Score = 39.5 bits (88), Expect = 0.005
Identities = 30/130 (23%), Positives = 57/130 (43%), Gaps = 2/130 (1%)
Query: 10 LYRSLPDILQREIMLSCYRGYIMRIPYFCDWAVSVIEDIVVMLKEKIYLANDIVAEPWIQ 69
+ L D L+ EI+ R + +P F + + + ++ L+ +++ D +
Sbjct: 328 ILNELNDPLREEIVNFNCRKLVATMPLFANADPNFVTAMLSKLRFEVFQPGDYIIREGAV 387
Query: 70 GDGLIIVDAGELAVYSVDDEETAHLIDGDYFGELSLITDKEVRTSYVVTITDSQILTLDK 129
G + + G V + +E L DG YFGE+ L+T K RT+ V T ++ +L
Sbjct: 388 GKKMYFIQHGVAGVITKSSKEMK-LTDGSYFGEICLLT-KGRRTASVRADTYCRLYSLSV 445
Query: 130 GAFRMYMRNH 139
F + +
Sbjct: 446 DNFNEVLEEY 455
>AF228520-1|AAF80179.1| 610|Homo sapiens cone photoreceptor
cGMP-gated cation channel beta-subunit protein.
Length = 610
Score = 39.1 bits (87), Expect = 0.007
Identities = 33/132 (25%), Positives = 57/132 (43%), Gaps = 1/132 (0%)
Query: 10 LYRSLPDILQREIMLSCYRGYIMRIPYFCDWAVSVIEDIVVMLKEKIYLANDIVAEPWIQ 69
L ++LP +Q + + I ++ F +I D+++ LK +YL D V +
Sbjct: 304 LLKTLPTTVQLALAIDVNFSIISKVDLFKGCDTQMIYDMLLRLKSVLYLPGDFVCKKGEI 363
Query: 70 GDGLIIVDAGELAVYSVDDEETAHLIDGDYFGELSLITDKEVRTSYVVTITDSQILTLDK 129
G + I+ GE+ V D T L+ L RT+ VV + +LTLDK
Sbjct: 364 GKEMYIIKHGEVQVLGGPD-GTKVLVTLKAGSVLLAAGGGNRRTANVVAHGFANLLTLDK 422
Query: 130 GAFRMYMRNHTD 141
+ + ++ D
Sbjct: 423 KTLQEILVHYPD 434
>AF488549-1|AAO49469.1| 890|Homo sapiens hyperpolarization
activated cyclic nucleotide-gated potassium channel
protein.
Length = 890
Score = 38.7 bits (86), Expect = 0.009
Identities = 30/123 (24%), Positives = 55/123 (44%), Gaps = 2/123 (1%)
Query: 10 LYRSLPDILQREIMLSCYRGYIMRIPYFCDWAVSVIEDIVVMLKEKIYLANDIVAEPWIQ 69
+ L D L+ EI+ R + +P F + + + ++ L+ +++ D +
Sbjct: 449 ILNELNDPLRGEIVNFNCRKLVATMPLFANADPNFVTAMLSKLRFEVFQPGDYIVREGAV 508
Query: 70 GDGLIIVDAGELAVYSVDDEETAHLIDGDYFGELSLITDKEVRTSYVVTITDSQILTLDK 129
G + + G V + +E L DG YFGE+ L+T K RT+ V T ++ +L
Sbjct: 509 GKKMYFIQHGVAGVITKSSKEMK-LTDGSYFGEICLLT-KGRRTASVRADTYCRLYSLSV 566
Query: 130 GAF 132
F
Sbjct: 567 DNF 569
>Z92868-1|CAB07437.1| 686|Homo sapiens cGMP-dependent protein
kinase type I beta protein.
Length = 686
Score = 38.3 bits (85), Expect = 0.012
Identities = 27/112 (24%), Positives = 51/112 (45%), Gaps = 6/112 (5%)
Query: 27 YRGYIMRIPYFCDWAVSVIEDIVVMLKEKIYLANDIVAEPWIQGDGLIIVDAGELAVYSV 86
Y ++ +P F ++ + +L+E Y + + +GD I+ G + V
Sbjct: 227 YMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTRE 286
Query: 87 D--DEETAHLI---DGDYFGELSLITDKEVRTSYVVTITDSQILTLDKGAFR 133
D E+ L GD+FGE +L ++VRT+ V+ L +D+ +F+
Sbjct: 287 DSPSEDPVFLRTLGKGDWFGEKAL-QGEDVRTANVIAAEAVTCLVIDRDSFK 337
>Z92867-1|CAB07436.1| 671|Homo sapiens cGMP-dependent protein
kinase type I alpha protein.
Length = 671
Score = 38.3 bits (85), Expect = 0.012
Identities = 27/112 (24%), Positives = 51/112 (45%), Gaps = 6/112 (5%)
Query: 27 YRGYIMRIPYFCDWAVSVIEDIVVMLKEKIYLANDIVAEPWIQGDGLIIVDAGELAVYSV 86
Y ++ +P F ++ + +L+E Y + + +GD I+ G + V
Sbjct: 212 YMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTRE 271
Query: 87 D--DEETAHLI---DGDYFGELSLITDKEVRTSYVVTITDSQILTLDKGAFR 133
D E+ L GD+FGE +L ++VRT+ V+ L +D+ +F+
Sbjct: 272 DSPSEDPVFLRTLGKGDWFGEKAL-QGEDVRTANVIAAEAVTCLVIDRDSFK 322
>Y07512-1|CAA68810.1| 686|Homo sapiens protein ( Human mRNA for
type I beta cGMP-dependent protein kinase (EC
2.7.1.37). ).
Length = 686
Score = 38.3 bits (85), Expect = 0.012
Identities = 27/112 (24%), Positives = 51/112 (45%), Gaps = 6/112 (5%)
Query: 27 YRGYIMRIPYFCDWAVSVIEDIVVMLKEKIYLANDIVAEPWIQGDGLIIVDAGELAVYSV 86
Y ++ +P F ++ + +L+E Y + + +GD I+ G + V
Sbjct: 227 YMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTRE 286
Query: 87 D--DEETAHLI---DGDYFGELSLITDKEVRTSYVVTITDSQILTLDKGAFR 133
D E+ L GD+FGE +L ++VRT+ V+ L +D+ +F+
Sbjct: 287 DSPSEDPVFLRTLGKGDWFGEKAL-QGEDVRTANVIAAEAVTCLVIDRDSFK 337
>D45864-1|BAA08297.1| 671|Homo sapiens cGMP-dependent protein
kinase type I alpha protein.
Length = 671
Score = 38.3 bits (85), Expect = 0.012
Identities = 27/112 (24%), Positives = 51/112 (45%), Gaps = 6/112 (5%)
Query: 27 YRGYIMRIPYFCDWAVSVIEDIVVMLKEKIYLANDIVAEPWIQGDGLIIVDAGELAVYSV 86
Y ++ +P F ++ + +L+E Y + + +GD I+ G + V
Sbjct: 212 YMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTRE 271
Query: 87 D--DEETAHLI---DGDYFGELSLITDKEVRTSYVVTITDSQILTLDKGAFR 133
D E+ L GD+FGE +L ++VRT+ V+ L +D+ +F+
Sbjct: 272 DSPSEDPVFLRTLGKGDWFGEKAL-QGEDVRTANVIAAEAVTCLVIDRDSFK 322
>BC127090-1|AAI27091.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 38.3 bits (85), Expect = 0.012
Identities = 27/112 (24%), Positives = 51/112 (45%), Gaps = 6/112 (5%)
Query: 27 YRGYIMRIPYFCDWAVSVIEDIVVMLKEKIYLANDIVAEPWIQGDGLIIVDAGELAVYSV 86
Y ++ +P F ++ + +L+E Y + + +GD I+ G + V
Sbjct: 227 YMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTRE 286
Query: 87 D--DEETAHLI---DGDYFGELSLITDKEVRTSYVVTITDSQILTLDKGAFR 133
D E+ L GD+FGE +L ++VRT+ V+ L +D+ +F+
Sbjct: 287 DSPSEDPVFLRTLGKGDWFGEKAL-QGEDVRTANVIAAEAVTCLVIDRDSFK 337
>AL928686-2|CAI40743.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 38.3 bits (85), Expect = 0.012
Identities = 27/112 (24%), Positives = 51/112 (45%), Gaps = 6/112 (5%)
Query: 27 YRGYIMRIPYFCDWAVSVIEDIVVMLKEKIYLANDIVAEPWIQGDGLIIVDAGELAVYSV 86
Y ++ +P F ++ + +L+E Y + + +GD I+ G + V
Sbjct: 227 YMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTRE 286
Query: 87 D--DEETAHLI---DGDYFGELSLITDKEVRTSYVVTITDSQILTLDKGAFR 133
D E+ L GD+FGE +L ++VRT+ V+ L +D+ +F+
Sbjct: 287 DSPSEDPVFLRTLGKGDWFGEKAL-QGEDVRTANVIAAEAVTCLVIDRDSFK 337
>AL928686-1|CAI40742.1| 659|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 659
Score = 38.3 bits (85), Expect = 0.012
Identities = 27/112 (24%), Positives = 51/112 (45%), Gaps = 6/112 (5%)
Query: 27 YRGYIMRIPYFCDWAVSVIEDIVVMLKEKIYLANDIVAEPWIQGDGLIIVDAGELAVYSV 86
Y ++ +P F ++ + +L+E Y + + +GD I+ G + V
Sbjct: 200 YMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTRE 259
Query: 87 D--DEETAHLI---DGDYFGELSLITDKEVRTSYVVTITDSQILTLDKGAFR 133
D E+ L GD+FGE +L ++VRT+ V+ L +D+ +F+
Sbjct: 260 DSPSEDPVFLRTLGKGDWFGEKAL-QGEDVRTANVIAAEAVTCLVIDRDSFK 310
>AL731537-3|CAI17115.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 38.3 bits (85), Expect = 0.012
Identities = 27/112 (24%), Positives = 51/112 (45%), Gaps = 6/112 (5%)
Query: 27 YRGYIMRIPYFCDWAVSVIEDIVVMLKEKIYLANDIVAEPWIQGDGLIIVDAGELAVYSV 86
Y ++ +P F ++ + +L+E Y + + +GD I+ G + V
Sbjct: 227 YMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTRE 286
Query: 87 D--DEETAHLI---DGDYFGELSLITDKEVRTSYVVTITDSQILTLDKGAFR 133
D E+ L GD+FGE +L ++VRT+ V+ L +D+ +F+
Sbjct: 287 DSPSEDPVFLRTLGKGDWFGEKAL-QGEDVRTANVIAAEAVTCLVIDRDSFK 337
>AL731537-2|CAI17114.1| 659|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 659
Score = 38.3 bits (85), Expect = 0.012
Identities = 27/112 (24%), Positives = 51/112 (45%), Gaps = 6/112 (5%)
Query: 27 YRGYIMRIPYFCDWAVSVIEDIVVMLKEKIYLANDIVAEPWIQGDGLIIVDAGELAVYSV 86
Y ++ +P F ++ + +L+E Y + + +GD I+ G + V
Sbjct: 200 YMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTRE 259
Query: 87 D--DEETAHLI---DGDYFGELSLITDKEVRTSYVVTITDSQILTLDKGAFR 133
D E+ L GD+FGE +L ++VRT+ V+ L +D+ +F+
Sbjct: 260 DSPSEDPVFLRTLGKGDWFGEKAL-QGEDVRTANVIAAEAVTCLVIDRDSFK 310
>AL391378-2|CAI39626.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 38.3 bits (85), Expect = 0.012
Identities = 27/112 (24%), Positives = 51/112 (45%), Gaps = 6/112 (5%)
Query: 27 YRGYIMRIPYFCDWAVSVIEDIVVMLKEKIYLANDIVAEPWIQGDGLIIVDAGELAVYSV 86
Y ++ +P F ++ + +L+E Y + + +GD I+ G + V
Sbjct: 227 YMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTRE 286
Query: 87 D--DEETAHLI---DGDYFGELSLITDKEVRTSYVVTITDSQILTLDKGAFR 133
D E+ L GD+FGE +L ++VRT+ V+ L +D+ +F+
Sbjct: 287 DSPSEDPVFLRTLGKGDWFGEKAL-QGEDVRTANVIAAEAVTCLVIDRDSFK 337
>AL391378-1|CAI39625.1| 659|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 659
Score = 38.3 bits (85), Expect = 0.012
Identities = 27/112 (24%), Positives = 51/112 (45%), Gaps = 6/112 (5%)
Query: 27 YRGYIMRIPYFCDWAVSVIEDIVVMLKEKIYLANDIVAEPWIQGDGLIIVDAGELAVYSV 86
Y ++ +P F ++ + +L+E Y + + +GD I+ G + V
Sbjct: 200 YMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTRE 259
Query: 87 D--DEETAHLI---DGDYFGELSLITDKEVRTSYVVTITDSQILTLDKGAFR 133
D E+ L GD+FGE +L ++VRT+ V+ L +D+ +F+
Sbjct: 260 DSPSEDPVFLRTLGKGDWFGEKAL-QGEDVRTANVIAAEAVTCLVIDRDSFK 310
>AL157399-2|CAI41305.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 38.3 bits (85), Expect = 0.012
Identities = 27/112 (24%), Positives = 51/112 (45%), Gaps = 6/112 (5%)
Query: 27 YRGYIMRIPYFCDWAVSVIEDIVVMLKEKIYLANDIVAEPWIQGDGLIIVDAGELAVYSV 86
Y ++ +P F ++ + +L+E Y + + +GD I+ G + V
Sbjct: 227 YMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTRE 286
Query: 87 D--DEETAHLI---DGDYFGELSLITDKEVRTSYVVTITDSQILTLDKGAFR 133
D E+ L GD+FGE +L ++VRT+ V+ L +D+ +F+
Sbjct: 287 DSPSEDPVFLRTLGKGDWFGEKAL-QGEDVRTANVIAAEAVTCLVIDRDSFK 337
>AL157399-1|CAI41304.1| 659|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 659
Score = 38.3 bits (85), Expect = 0.012
Identities = 27/112 (24%), Positives = 51/112 (45%), Gaps = 6/112 (5%)
Query: 27 YRGYIMRIPYFCDWAVSVIEDIVVMLKEKIYLANDIVAEPWIQGDGLIIVDAGELAVYSV 86
Y ++ +P F ++ + +L+E Y + + +GD I+ G + V
Sbjct: 200 YMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTRE 259
Query: 87 D--DEETAHLI---DGDYFGELSLITDKEVRTSYVVTITDSQILTLDKGAFR 133
D E+ L GD+FGE +L ++VRT+ V+ L +D+ +F+
Sbjct: 260 DSPSEDPVFLRTLGKGDWFGEKAL-QGEDVRTANVIAAEAVTCLVIDRDSFK 310
>AJ133727-1|CAB42630.1| 889|Homo sapiens
hyperpolarization-activated cyclic nucleotide-gated
channel hHCN2 protein.
Length = 889
Score = 38.3 bits (85), Expect = 0.012
Identities = 28/122 (22%), Positives = 57/122 (46%), Gaps = 2/122 (1%)
Query: 18 LQREIMLSCYRGYIMRIPYFCDWAVSVIEDIVVMLKEKIYLANDIVAEPWIQGDGLIIVD 77
L+ EI+ R + +P F + + + ++ LK +++ D + G + +
Sbjct: 526 LREEIVNFNCRKLVASMPLFANADPNFVTAMLTKLKFEVFQPGDYIIREGTIGKKMYFIQ 585
Query: 78 AGELAVYSVDDEETAHLIDGDYFGELSLITDKEVRTSYVVTITDSQILTLDKGAFRMYMR 137
G ++V + ++E L DG YFGE+ L+T + RT+ V T ++ +L F +
Sbjct: 586 HGVVSVLTKGNKEMK-LSDGSYFGEICLLT-RGRRTASVRADTYCRLYSLSVDNFNEVLE 643
Query: 138 NH 139
+
Sbjct: 644 EY 645
>AJ012582-1|CAB42602.1| 889|Homo sapiens
hyperpolarization-activated cation channel HCN2 protein.
Length = 889
Score = 38.3 bits (85), Expect = 0.012
Identities = 28/122 (22%), Positives = 57/122 (46%), Gaps = 2/122 (1%)
Query: 18 LQREIMLSCYRGYIMRIPYFCDWAVSVIEDIVVMLKEKIYLANDIVAEPWIQGDGLIIVD 77
L+ EI+ R + +P F + + + ++ LK +++ D + G + +
Sbjct: 526 LREEIVNFNCRKLVASMPLFANADPNFVTAMLTKLKFEVFQPGDYIIREGTIGKKMYFIQ 585
Query: 78 AGELAVYSVDDEETAHLIDGDYFGELSLITDKEVRTSYVVTITDSQILTLDKGAFRMYMR 137
G ++V + ++E L DG YFGE+ L+T + RT+ V T ++ +L F +
Sbjct: 586 HGVVSVLTKGNKEMK-LSDGSYFGEICLLT-RGRRTASVRADTYCRLYSLSVDNFNEVLE 643
Query: 138 NH 139
+
Sbjct: 644 EY 645
>AF065164-1|AAC28444.2| 889|Homo sapiens
hyperpolarization-activated, cyclic nucleotide-gated
channel 2 protein.
Length = 889
Score = 38.3 bits (85), Expect = 0.012
Identities = 28/122 (22%), Positives = 57/122 (46%), Gaps = 2/122 (1%)
Query: 18 LQREIMLSCYRGYIMRIPYFCDWAVSVIEDIVVMLKEKIYLANDIVAEPWIQGDGLIIVD 77
L+ EI+ R + +P F + + + ++ LK +++ D + G + +
Sbjct: 526 LREEIVNFNCRKLVASMPLFANADPNFVTAMLTKLKFEVFQPGDYIIREGTIGKKMYFIQ 585
Query: 78 AGELAVYSVDDEETAHLIDGDYFGELSLITDKEVRTSYVVTITDSQILTLDKGAFRMYMR 137
G ++V + ++E L DG YFGE+ L+T + RT+ V T ++ +L F +
Sbjct: 586 HGVVSVLTKGNKEMK-LSDGSYFGEICLLT-RGRRTASVRADTYCRLYSLSVDNFNEVLE 643
Query: 138 NH 139
+
Sbjct: 644 EY 645
>AF064877-1|AAC39760.1| 597|Homo sapiens ion channel BCNG-2
protein.
Length = 597
Score = 38.3 bits (85), Expect = 0.012
Identities = 28/122 (22%), Positives = 57/122 (46%), Gaps = 2/122 (1%)
Query: 18 LQREIMLSCYRGYIMRIPYFCDWAVSVIEDIVVMLKEKIYLANDIVAEPWIQGDGLIIVD 77
L+ EI+ R + +P F + + + ++ LK +++ D + G + +
Sbjct: 380 LREEIVNFNCRKLVASMPLFANADPNFVTAMLTKLKFEVFQPGDYIIREGTIGKKMYFIQ 439
Query: 78 AGELAVYSVDDEETAHLIDGDYFGELSLITDKEVRTSYVVTITDSQILTLDKGAFRMYMR 137
G ++V + ++E L DG YFGE+ L+T + RT+ V T ++ +L F +
Sbjct: 440 HGVVSVLTKGNKEMK-LSDGSYFGEICLLT-RGRRTASVRADTYCRLYSLSVDNFNEVLE 497
Query: 138 NH 139
+
Sbjct: 498 EY 499
>BC075800-1|AAH75800.1| 418|Homo sapiens protein kinase,
cAMP-dependent, regulatory, type II, beta protein.
Length = 418
Score = 36.3 bits (80), Expect = 0.049
Identities = 30/116 (25%), Positives = 51/116 (43%), Gaps = 11/116 (9%)
Query: 27 YRGYIMRIPYFCDWAVSVIEDIVVMLKEKIYLANDIVAEPWIQGDGLIIVDAGELAVY-- 84
Y +I +P+ S +V ++ K+Y + + D IV++GE+ +
Sbjct: 267 YESFIESLPFLKSLEFSERLKVVDVIGTKVYNDGEQIIAQGDSADSFFIVESGEVKITMK 326
Query: 85 -----SVDDE---ETAHLIDGDYFGELSLITDKEVRTSYVVTITDSQILTLDKGAF 132
V++ E A G YFGEL+L+T+K R + I + L +D AF
Sbjct: 327 RKGKSEVEENGAVEIARCSRGQYFGELALVTNKP-RAASAHAIGTVKCLAMDVQAF 381
>Y16106-1|CAA76073.1| 734|Homo sapiens cGMP-dependant protein
kinase protein.
Length = 734
Score = 34.7 bits (76), Expect = 0.15
Identities = 25/111 (22%), Positives = 47/111 (42%), Gaps = 5/111 (4%)
Query: 27 YRGYIMRIPYFCDWAVSVIEDIVVMLKEKIYLANDIVAEPWIQGDGLIIVDAGELAV-YS 85
YR ++ + + + I+ L+ + Y D + +G I+ G++ V S
Sbjct: 277 YRNFLRSVSLLKNLPEDKLTKIIDCLEVEYYDKGDYIIREGEEGSTFFILAKGKVKVTQS 336
Query: 86 VDDEETAHLID----GDYFGELSLITDKEVRTSYVVTITDSQILTLDKGAF 132
+ + LI G+YFGE +LI+D + + D L +D+ F
Sbjct: 337 TEGHDQPQLIKTLQKGEYFGEKALISDDVRSANIIAEENDVACLVIDRETF 387
Score = 29.5 bits (63), Expect = 5.6
Identities = 22/93 (23%), Positives = 46/93 (49%), Gaps = 2/93 (2%)
Query: 45 IEDIVVMLKEKIYLANDIVAEPWIQGDGLIIVDAGELAVYSVDDEETAHLIDGDYFGELS 104
I+D+V + + Y + + G+ + ++ G L V+ ++ + + FGEL+
Sbjct: 177 IKDMVECMYGRNYQQGSYIIKQGEPGNHIFVLAEGRLEVFQ-GEKLLSSIPMWTTFGELA 235
Query: 105 LITDKEVRTSYVVTITDSQILTLDKGAFRMYMR 137
++ + RT+ V IT+ + LD+ F+ MR
Sbjct: 236 ILYNC-TRTASVKAITNVKTWALDREVFQNIMR 267
>X94612-1|CAA64318.1| 762|Homo sapiens Type II cGMP-dependent
protein kinase protein.
Length = 762
Score = 34.7 bits (76), Expect = 0.15
Identities = 25/111 (22%), Positives = 47/111 (42%), Gaps = 5/111 (4%)
Query: 27 YRGYIMRIPYFCDWAVSVIEDIVVMLKEKIYLANDIVAEPWIQGDGLIIVDAGELAV-YS 85
YR ++ + + + I+ L+ + Y D + +G I+ G++ V S
Sbjct: 277 YRNFLRSVSLLKNLPEDKLTKIIDCLEVEYYDKGDYIIREGEEGSTFFILAKGKVKVTQS 336
Query: 86 VDDEETAHLID----GDYFGELSLITDKEVRTSYVVTITDSQILTLDKGAF 132
+ + LI G+YFGE +LI+D + + D L +D+ F
Sbjct: 337 TEGHDQPQLIKTLQKGEYFGEKALISDDVRSANIIAEENDVACLVIDRETF 387
Score = 29.5 bits (63), Expect = 5.6
Identities = 22/93 (23%), Positives = 46/93 (49%), Gaps = 2/93 (2%)
Query: 45 IEDIVVMLKEKIYLANDIVAEPWIQGDGLIIVDAGELAVYSVDDEETAHLIDGDYFGELS 104
I+D+V + + Y + + G+ + ++ G L V+ ++ + + FGEL+
Sbjct: 177 IKDMVECMYGRNYQQGSYIIKQGEPGNHIFVLAEGRLEVFQ-GEKLLSSIPMWTTFGELA 235
Query: 105 LITDKEVRTSYVVTITDSQILTLDKGAFRMYMR 137
++ + RT+ V IT+ + LD+ F+ MR
Sbjct: 236 ILYNC-TRTASVKAITNVKTWALDREVFQNIMR 267
>D70899-1|BAA18934.1| 762|Homo sapiens cGMP-dependent protein
kinase II protein.
Length = 762
Score = 34.7 bits (76), Expect = 0.15
Identities = 25/111 (22%), Positives = 47/111 (42%), Gaps = 5/111 (4%)
Query: 27 YRGYIMRIPYFCDWAVSVIEDIVVMLKEKIYLANDIVAEPWIQGDGLIIVDAGELAV-YS 85
YR ++ + + + I+ L+ + Y D + +G I+ G++ V S
Sbjct: 277 YRNFLRSVSLLKNLPEDKLTKIIDCLEVEYYDKGDYIIREGEEGSTFFILAKGKVKVTQS 336
Query: 86 VDDEETAHLID----GDYFGELSLITDKEVRTSYVVTITDSQILTLDKGAF 132
+ + LI G+YFGE +LI+D + + D L +D+ F
Sbjct: 337 TEGHDQPQLIKTLQKGEYFGEKALISDDVRSANIIAEENDVACLVIDRETF 387
Score = 29.5 bits (63), Expect = 5.6
Identities = 22/93 (23%), Positives = 46/93 (49%), Gaps = 2/93 (2%)
Query: 45 IEDIVVMLKEKIYLANDIVAEPWIQGDGLIIVDAGELAVYSVDDEETAHLIDGDYFGELS 104
I+D+V + + Y + + G+ + ++ G L V+ ++ + + FGEL+
Sbjct: 177 IKDMVECMYGRNYQQGSYIIKQGEPGNHIFVLAEGRLEVFQ-GEKLLSSIPMWTTFGELA 235
Query: 105 LITDKEVRTSYVVTITDSQILTLDKGAFRMYMR 137
++ + RT+ V IT+ + LD+ F+ MR
Sbjct: 236 ILYNC-TRTASVKAITNVKTWALDREVFQNIMR 267
>M31158-1|AAA60099.1| 418|Homo sapiens cAMP-dependent protein
kinase subunit RII-beta protein.
Length = 418
Score = 34.3 bits (75), Expect = 0.20
Identities = 29/116 (25%), Positives = 50/116 (43%), Gaps = 11/116 (9%)
Query: 27 YRGYIMRIPYFCDWAVSVIEDIVVMLKEKIYLANDIVAEPWIQGDGLIIVDAGELAVY-- 84
Y +I +P+ S +V ++ K+Y + + D IV++GE+ +
Sbjct: 267 YESFIESLPFLKSLEFSERLKVVDVIGTKVYNDGEQIIAQGDSADSFFIVESGEVKITMK 326
Query: 85 -----SVDDE---ETAHLIDGDYFGELSLITDKEVRTSYVVTITDSQILTLDKGAF 132
V++ E G YFGEL+L+T+K R + I + L +D AF
Sbjct: 327 RKGKSEVEENGAVEMPRCSRGQYFGELALVTNKP-RAASAHAIGTVKCLAMDVQAF 381
>BT007225-1|AAP35889.1| 382|Homo sapiens protein kinase,
cAMP-dependent, regulatory, type II, alpha protein.
Length = 382
Score = 33.1 bits (72), Expect = 0.46
Identities = 32/107 (29%), Positives = 47/107 (43%), Gaps = 14/107 (13%)
Query: 27 YRGYIMRIPYFCDWAVSVIEDIVVMLKEKIYLAND-IVAEPWIQGDGLIIVDAGELAVYS 85
+ +I +P VS IV ++ EKIY + I+ + DG G V
Sbjct: 252 FESFIESVPLLKSLEVSERMKIVDVIGEKIYKDGERIITQTKSNKDG------GNQEV-- 303
Query: 86 VDDEETAHLIDGDYFGELSLITDKEVRTSYVVTITDSQILTLDKGAF 132
E A G YFGEL+L+T+K R + + D + L +D AF
Sbjct: 304 ----EIARCHKGQYFGELALVTNKP-RAASAYAVGDVKCLVMDVQAF 345
Score = 31.9 bits (69), Expect = 1.1
Identities = 21/92 (22%), Positives = 44/92 (47%), Gaps = 4/92 (4%)
Query: 45 IEDIVVMLKEKIYLANDIVAEPWIQGDGLIIVDAGELAVYSVDDEETAHLIDGD---YFG 101
+ ++ + E+I A++ V + GD +++ G + D +T + D FG
Sbjct: 148 LSQVLDAMFERIVKADEHVIDQGDDGDNFYVIERGTYDILVTKDNQTRSVGQYDNRGSFG 207
Query: 102 ELSLITDKEVRTSYVVTITDSQILTLDKGAFR 133
EL+L+ + R + +V ++ + LD+ FR
Sbjct: 208 ELALMYNTP-RAATIVATSEGSLWGLDRVTFR 238
>BC002763-1|AAH02763.1| 382|Homo sapiens PRKAR2A protein protein.
Length = 382
Score = 33.1 bits (72), Expect = 0.46
Identities = 32/107 (29%), Positives = 47/107 (43%), Gaps = 14/107 (13%)
Query: 27 YRGYIMRIPYFCDWAVSVIEDIVVMLKEKIYLAND-IVAEPWIQGDGLIIVDAGELAVYS 85
+ +I +P VS IV ++ EKIY + I+ + DG G V
Sbjct: 252 FESFIESVPLLKSLEVSERMKIVDVIGEKIYKDGERIITQTKSNKDG------GNQEV-- 303
Query: 86 VDDEETAHLIDGDYFGELSLITDKEVRTSYVVTITDSQILTLDKGAF 132
E A G YFGEL+L+T+K R + + D + L +D AF
Sbjct: 304 ----EIARCHKGQYFGELALVTNKP-RAASAYAVGDVKCLVMDVQAF 345
Score = 31.9 bits (69), Expect = 1.1
Identities = 21/92 (22%), Positives = 44/92 (47%), Gaps = 4/92 (4%)
Query: 45 IEDIVVMLKEKIYLANDIVAEPWIQGDGLIIVDAGELAVYSVDDEETAHLIDGD---YFG 101
+ ++ + E+I A++ V + GD +++ G + D +T + D FG
Sbjct: 148 LSQVLDAMFERIVKADEHVIDQGDDGDNFYVIERGTYDILVTKDNQTRSVGQYDNRGSFG 207
Query: 102 ELSLITDKEVRTSYVVTITDSQILTLDKGAFR 133
EL+L+ + R + +V ++ + LD+ FR
Sbjct: 208 ELALMYNTP-RAATIVATSEGSLWGLDRVTFR 238
>U78516-1|AAD03422.1| 1011|Homo sapiens cAMP-regulated guanine
nucleotide exchange factor II protein.
Length = 1011
Score = 30.7 bits (66), Expect = 2.4
Identities = 19/70 (27%), Positives = 31/70 (44%)
Query: 69 QGDGLIIVDAGELAVYSVDDEETAHLIDGDYFGELSLITDKEVRTSYVVTITDSQILTLD 128
+G I+ G + V L +GD FG+L+L+ D S V+ + L +D
Sbjct: 390 EGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVD 449
Query: 129 KGAFRMYMRN 138
K F +R+
Sbjct: 450 KEDFNRILRD 459
>BC040183-1|AAH40183.1| 867|Homo sapiens RAPGEF4 protein protein.
Length = 867
Score = 30.7 bits (66), Expect = 2.4
Identities = 19/70 (27%), Positives = 31/70 (44%)
Query: 69 QGDGLIIVDAGELAVYSVDDEETAHLIDGDYFGELSLITDKEVRTSYVVTITDSQILTLD 128
+G I+ G + V L +GD FG+L+L+ D S V+ + L +D
Sbjct: 246 EGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVD 305
Query: 129 KGAFRMYMRN 138
K F +R+
Sbjct: 306 KEDFNRILRD 315
>BC024004-1|AAH24004.1| 1011|Homo sapiens Rap guanine nucleotide
exchange factor (GEF) 4 protein.
Length = 1011
Score = 30.7 bits (66), Expect = 2.4
Identities = 19/70 (27%), Positives = 31/70 (44%)
Query: 69 QGDGLIIVDAGELAVYSVDDEETAHLIDGDYFGELSLITDKEVRTSYVVTITDSQILTLD 128
+G I+ G + V L +GD FG+L+L+ D S V+ + L +D
Sbjct: 390 EGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVD 449
Query: 129 KGAFRMYMRN 138
K F +R+
Sbjct: 450 KEDFNRILRD 459
>AB209681-1|BAD92918.1| 643|Homo sapiens RAP
guanine-nucleotide-exchange factor 4 variant protein.
Length = 643
Score = 30.7 bits (66), Expect = 2.4
Identities = 19/70 (27%), Positives = 31/70 (44%)
Query: 69 QGDGLIIVDAGELAVYSVDDEETAHLIDGDYFGELSLITDKEVRTSYVVTITDSQILTLD 128
+G I+ G + V L +GD FG+L+L+ D S V+ + L +D
Sbjct: 22 EGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVD 81
Query: 129 KGAFRMYMRN 138
K F +R+
Sbjct: 82 KEDFNRILRD 91
>AB027471-1|BAB72179.1| 1011|Homo sapiens cAMP-GEFII protein.
Length = 1011
Score = 30.7 bits (66), Expect = 2.4
Identities = 19/70 (27%), Positives = 31/70 (44%)
Query: 69 QGDGLIIVDAGELAVYSVDDEETAHLIDGDYFGELSLITDKEVRTSYVVTITDSQILTLD 128
+G I+ G + V L +GD FG+L+L+ D S V+ + L +D
Sbjct: 390 EGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVD 449
Query: 129 KGAFRMYMRN 138
K F +R+
Sbjct: 450 KEDFNRILRD 459
>Y10807-1|CAA71765.1| 343|Homo sapiens arginine methyltransferase
protein.
Length = 343
Score = 30.3 bits (65), Expect = 3.2
Identities = 17/66 (25%), Positives = 31/66 (46%), Gaps = 4/66 (6%)
Query: 65 EPWIQGDGLIIVDAGELAVYSVDDEE----TAHLIDGDYFGELSLITDKEVRTSYVVTIT 120
+ W+ DGLI D L V +++D + H + Y ++S I D ++ V +
Sbjct: 154 DKWLAPDGLIFPDRATLYVTAIEDRQYKDYKIHWWENVYGFDMSCIKDVAIKEPLVDVVD 213
Query: 121 DSQILT 126
Q++T
Sbjct: 214 PKQLVT 219
>Y10806-1|CAA71764.1| 361|Homo sapiens arginine methyltransferase
protein.
Length = 361
Score = 30.3 bits (65), Expect = 3.2
Identities = 17/66 (25%), Positives = 31/66 (46%), Gaps = 4/66 (6%)
Query: 65 EPWIQGDGLIIVDAGELAVYSVDDEE----TAHLIDGDYFGELSLITDKEVRTSYVVTIT 120
+ W+ DGLI D L V +++D + H + Y ++S I D ++ V +
Sbjct: 172 DKWLAPDGLIFPDRATLYVTAIEDRQYKDYKIHWWENVYGFDMSCIKDVAIKEPLVDVVD 231
Query: 121 DSQILT 126
Q++T
Sbjct: 232 PKQLVT 237
>Y10805-1|CAA71763.1| 347|Homo sapiens arginine methyltransferase
protein.
Length = 347
Score = 30.3 bits (65), Expect = 3.2
Identities = 17/66 (25%), Positives = 31/66 (46%), Gaps = 4/66 (6%)
Query: 65 EPWIQGDGLIIVDAGELAVYSVDDEE----TAHLIDGDYFGELSLITDKEVRTSYVVTIT 120
+ W+ DGLI D L V +++D + H + Y ++S I D ++ V +
Sbjct: 158 DKWLAPDGLIFPDRATLYVTAIEDRQYKDYKIHWWENVYGFDMSCIKDVAIKEPLVDVVD 217
Query: 121 DSQILT 126
Q++T
Sbjct: 218 PKQLVT 223
>CR407608-1|CAG28536.1| 347|Homo sapiens HRMT1L2 protein.
Length = 347
Score = 30.3 bits (65), Expect = 3.2
Identities = 17/66 (25%), Positives = 31/66 (46%), Gaps = 4/66 (6%)
Query: 65 EPWIQGDGLIIVDAGELAVYSVDDEE----TAHLIDGDYFGELSLITDKEVRTSYVVTIT 120
+ W+ DGLI D L V +++D + H + Y ++S I D ++ V +
Sbjct: 158 DKWLAPDGLIFPDRATLYVTAIEDRQYKDYKIHWWENVYGFDMSCIKDVAIKEPLVDVVD 217
Query: 121 DSQILT 126
Q++T
Sbjct: 218 PKQLVT 223
>BC109283-1|AAI09284.2| 343|Homo sapiens protein arginine
methyltransferase 1 protein.
Length = 343
Score = 30.3 bits (65), Expect = 3.2
Identities = 17/66 (25%), Positives = 31/66 (46%), Gaps = 4/66 (6%)
Query: 65 EPWIQGDGLIIVDAGELAVYSVDDEE----TAHLIDGDYFGELSLITDKEVRTSYVVTIT 120
+ W+ DGLI D L V +++D + H + Y ++S I D ++ V +
Sbjct: 154 DKWLAPDGLIFPDRATLYVTAIEDRQYKDYKIHWWENVYGFDMSCIKDVAIKEPLVDVVD 213
Query: 121 DSQILT 126
Q++T
Sbjct: 214 PKQLVT 219
>BC109282-1|AAI09283.2| 343|Homo sapiens protein arginine
methyltransferase 1 protein.
Length = 343
Score = 30.3 bits (65), Expect = 3.2
Identities = 17/66 (25%), Positives = 31/66 (46%), Gaps = 4/66 (6%)
Query: 65 EPWIQGDGLIIVDAGELAVYSVDDEE----TAHLIDGDYFGELSLITDKEVRTSYVVTIT 120
+ W+ DGLI D L V +++D + H + Y ++S I D ++ V +
Sbjct: 154 DKWLAPDGLIFPDRATLYVTAIEDRQYKDYKIHWWENVYGFDMSCIKDVAIKEPLVDVVD 213
Query: 121 DSQILT 126
Q++T
Sbjct: 214 PKQLVT 219
>BC019268-1|AAH19268.2| 352|Homo sapiens PRMT1 protein protein.
Length = 352
Score = 30.3 bits (65), Expect = 3.2
Identities = 17/66 (25%), Positives = 31/66 (46%), Gaps = 4/66 (6%)
Query: 65 EPWIQGDGLIIVDAGELAVYSVDDEE----TAHLIDGDYFGELSLITDKEVRTSYVVTIT 120
+ W+ DGLI D L V +++D + H + Y ++S I D ++ V +
Sbjct: 163 DKWLAPDGLIFPDRATLYVTAIEDRQYKDYKIHWWENVYGFDMSCIKDVAIKEPLVDVVD 222
Query: 121 DSQILT 126
Q++T
Sbjct: 223 PKQLVT 228
>AY775289-1|AAV41837.1| 327|Homo sapiens protein arginine
methyltransferase 1 isoform 4 protein.
Length = 327
Score = 30.3 bits (65), Expect = 3.2
Identities = 17/66 (25%), Positives = 31/66 (46%), Gaps = 4/66 (6%)
Query: 65 EPWIQGDGLIIVDAGELAVYSVDDEE----TAHLIDGDYFGELSLITDKEVRTSYVVTIT 120
+ W+ DGLI D L V +++D + H + Y ++S I D ++ V +
Sbjct: 138 DKWLAPDGLIFPDRATLYVTAIEDRQYKDYKIHWWENVYGFDMSCIKDVAIKEPLVDVVD 197
Query: 121 DSQILT 126
Q++T
Sbjct: 198 PKQLVT 203
>AF222689-3|AAF62894.1| 347|Homo sapiens protein arginine
N-methyltransferase 1-variant 3 protein.
Length = 347
Score = 30.3 bits (65), Expect = 3.2
Identities = 17/66 (25%), Positives = 31/66 (46%), Gaps = 4/66 (6%)
Query: 65 EPWIQGDGLIIVDAGELAVYSVDDEE----TAHLIDGDYFGELSLITDKEVRTSYVVTIT 120
+ W+ DGLI D L V +++D + H + Y ++S I D ++ V +
Sbjct: 158 DKWLAPDGLIFPDRATLYVTAIEDRQYKDYKIHWWENVYGFDMSCIKDVAIKEPLVDVVD 217
Query: 121 DSQILT 126
Q++T
Sbjct: 218 PKQLVT 223
>AF222689-2|AAF62895.1| 343|Homo sapiens protein arginine
N-methyltransferase 1-variant 1 protein.
Length = 343
Score = 30.3 bits (65), Expect = 3.2
Identities = 17/66 (25%), Positives = 31/66 (46%), Gaps = 4/66 (6%)
Query: 65 EPWIQGDGLIIVDAGELAVYSVDDEE----TAHLIDGDYFGELSLITDKEVRTSYVVTIT 120
+ W+ DGLI D L V +++D + H + Y ++S I D ++ V +
Sbjct: 154 DKWLAPDGLIFPDRATLYVTAIEDRQYKDYKIHWWENVYGFDMSCIKDVAIKEPLVDVVD 213
Query: 121 DSQILT 126
Q++T
Sbjct: 214 PKQLVT 219
>AF222689-1|AAF62893.1| 361|Homo sapiens protein arginine
N-methyltransferase 1-variant 2 protein.
Length = 361
Score = 30.3 bits (65), Expect = 3.2
Identities = 17/66 (25%), Positives = 31/66 (46%), Gaps = 4/66 (6%)
Query: 65 EPWIQGDGLIIVDAGELAVYSVDDEE----TAHLIDGDYFGELSLITDKEVRTSYVVTIT 120
+ W+ DGLI D L V +++D + H + Y ++S I D ++ V +
Sbjct: 172 DKWLAPDGLIFPDRATLYVTAIEDRQYKDYKIHWWENVYGFDMSCIKDVAIKEPLVDVVD 231
Query: 121 DSQILT 126
Q++T
Sbjct: 232 PKQLVT 237
>AC004492-1|AAC08318.1| 112|Homo sapiens CAMP-DEPENDENT PROTEIN
KINASE TYPE II-BETA REGULATORY CHAIN protein.
Length = 112
Score = 29.1 bits (62), Expect = 7.5
Identities = 17/43 (39%), Positives = 23/43 (53%), Gaps = 1/43 (2%)
Query: 90 ETAHLIDGDYFGELSLITDKEVRTSYVVTITDSQILTLDKGAF 132
E A G YFGEL+L+T+K R + I + L +D AF
Sbjct: 34 EIARCSRGQYFGELALVTNKP-RAASAHAIGTVKCLAMDVQAF 75
>BC092404-1|AAH92404.1| 881|Homo sapiens Rap guanine nucleotide
exchange factor (GEF) 3 protein.
Length = 881
Score = 28.7 bits (61), Expect = 9.9
Identities = 20/89 (22%), Positives = 39/89 (43%)
Query: 50 VMLKEKIYLANDIVAEPWIQGDGLIIVDAGELAVYSVDDEETAHLIDGDYFGELSLITDK 109
V+L E A ++ +G I+ G + V + L +GD FG+L+L+ D
Sbjct: 218 VLLFEPHSKAGTVLFSQGDKGTSWYIIWKGSVNVVTHGKGLVTTLHEGDDFGQLALVNDA 277
Query: 110 EVRTSYVVTITDSQILTLDKGAFRMYMRN 138
+ ++ + L +DK F +++
Sbjct: 278 PRAATIILREDNCHFLRVDKQDFNRIIKD 306
>BC068477-1|AAH68477.1| 343|Homo sapiens RAPGEF3 protein protein.
Length = 343
Score = 28.7 bits (61), Expect = 9.9
Identities = 20/89 (22%), Positives = 39/89 (43%)
Query: 50 VMLKEKIYLANDIVAEPWIQGDGLIIVDAGELAVYSVDDEETAHLIDGDYFGELSLITDK 109
V+L E A ++ +G I+ G + V + L +GD FG+L+L+ D
Sbjct: 218 VLLFEPHSKAGTVLFSQGDKGTSWYIIWKGSVNVVTHGKGLVTTLHEGDDFGQLALVNDA 277
Query: 110 EVRTSYVVTITDSQILTLDKGAFRMYMRN 138
+ ++ + L +DK F +++
Sbjct: 278 PRAATIILREDNCHFLRVDKQDFNRIIKD 306
>BC062688-1|AAH62688.1| 312|Homo sapiens PRKG1 protein protein.
Length = 312
Score = 28.7 bits (61), Expect = 9.9
Identities = 20/84 (23%), Positives = 36/84 (42%), Gaps = 5/84 (5%)
Query: 27 YRGYIMRIPYFCDWAVSVIEDIVVMLKEKIYLANDIVAEPWIQGDGLIIVDAGELAVYSV 86
Y ++ +P F ++ + +L+E Y + + +GD I+ G + V
Sbjct: 227 YMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTRE 286
Query: 87 D--DEETAHLI---DGDYFGELSL 105
D E+ L GD+FGE +L
Sbjct: 287 DSPSEDPVFLRTLGKGDWFGEKAL 310
>BC017728-1|AAH17728.1| 881|Homo sapiens Rap guanine nucleotide
exchange factor (GEF) 3 protein.
Length = 881
Score = 28.7 bits (61), Expect = 9.9
Identities = 20/89 (22%), Positives = 39/89 (43%)
Query: 50 VMLKEKIYLANDIVAEPWIQGDGLIIVDAGELAVYSVDDEETAHLIDGDYFGELSLITDK 109
V+L E A ++ +G I+ G + V + L +GD FG+L+L+ D
Sbjct: 218 VLLFEPHSKAGTVLFSQGDKGTSWYIIWKGSVNVVTHGKGLVTTLHEGDDFGQLALVNDA 277
Query: 110 EVRTSYVVTITDSQILTLDKGAFRMYMRN 138
+ ++ + L +DK F +++
Sbjct: 278 PRAATIILREDNCHFLRVDKQDFNRIIKD 306
>AL391378-3|CAI39627.1| 181|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 181
Score = 28.7 bits (61), Expect = 9.9
Identities = 20/84 (23%), Positives = 36/84 (42%), Gaps = 5/84 (5%)
Query: 27 YRGYIMRIPYFCDWAVSVIEDIVVMLKEKIYLANDIVAEPWIQGDGLIIVDAGELAVYSV 86
Y ++ +P F ++ + +L+E Y + + +GD I+ G + V
Sbjct: 85 YMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTRE 144
Query: 87 D--DEETAHLI---DGDYFGELSL 105
D E+ L GD+FGE +L
Sbjct: 145 DSPSEDPVFLRTLGKGDWFGEKAL 168
>AL157399-3|CAI41306.1| 181|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 181
Score = 28.7 bits (61), Expect = 9.9
Identities = 20/84 (23%), Positives = 36/84 (42%), Gaps = 5/84 (5%)
Query: 27 YRGYIMRIPYFCDWAVSVIEDIVVMLKEKIYLANDIVAEPWIQGDGLIIVDAGELAVYSV 86
Y ++ +P F ++ + +L+E Y + + +GD I+ G + V
Sbjct: 85 YMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTRE 144
Query: 87 D--DEETAHLI---DGDYFGELSL 105
D E+ L GD+FGE +L
Sbjct: 145 DSPSEDPVFLRTLGKGDWFGEKAL 168
>AF103905-1|AAC83381.1| 881|Homo sapiens Rap1 guanine-nucleotide
exchange factor protein.
Length = 881
Score = 28.7 bits (61), Expect = 9.9
Identities = 20/89 (22%), Positives = 39/89 (43%)
Query: 50 VMLKEKIYLANDIVAEPWIQGDGLIIVDAGELAVYSVDDEETAHLIDGDYFGELSLITDK 109
V+L E A ++ +G I+ G + V + L +GD FG+L+L+ D
Sbjct: 218 VLLFEPHSKAGTVLFSQGDKGTSWYIIWKGSVNVVTHGKGLVTTLHEGDDFGQLALVNDA 277
Query: 110 EVRTSYVVTITDSQILTLDKGAFRMYMRN 138
+ ++ + L +DK F +++
Sbjct: 278 PRAATIILREDNCHFLRVDKQDFNRIIKD 306
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.323 0.139 0.419
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 20,223,209
Number of Sequences: 224733
Number of extensions: 754732
Number of successful extensions: 1182
Number of sequences better than 10.0: 83
Number of HSP's better than 10.0 without gapping: 24
Number of HSP's successfully gapped in prelim test: 59
Number of HSP's that attempted gapping in prelim test: 1130
Number of HSP's gapped (non-prelim): 99
length of query: 161
length of database: 73,234,838
effective HSP length: 84
effective length of query: 77
effective length of database: 54,357,266
effective search space: 4185509482
effective search space used: 4185509482
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.9 bits)
S2: 61 (28.7 bits)
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