Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA002036-TA|BGIBMGA002036-PA|IPR013098|Immunoglobulin
I-set, IPR007110|Immunoglobulin-like, IPR003598|Immunoglobulin subtype
2, IPR003599|Immunoglobulin subtype
(220 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AL670729-3|CAH71673.1| 6620|Homo sapiens obscurin, cytoskeletal ... 96 7e-20
AL359510-13|CAI15072.1| 6620|Homo sapiens obscurin, cytoskeletal... 96 7e-20
AL353593-3|CAI19285.1| 6620|Homo sapiens obscurin, cytoskeletal ... 96 7e-20
AJ002535-1|CAC44768.1| 6620|Homo sapiens obscurin protein. 96 7e-20
U48959-1|AAC18423.2| 1914|Homo sapiens myosin light chain kinase... 95 1e-19
AY424270-1|AAR29062.1| 1914|Homo sapiens myosin lignt chain poly... 95 1e-19
AY424269-1|AAR29061.1| 1845|Homo sapiens myosin light chain poly... 95 1e-19
AY339601-1|AAQ02673.1| 1914|Homo sapiens long myosin light chain... 95 1e-19
AF069603-1|AAD15923.1| 1793|Homo sapiens myosin light chain kina... 95 1e-19
AF069602-1|AAD15922.1| 1862|Homo sapiens myosin light chain kina... 95 1e-19
AF069601-1|AAD15921.2| 1845|Homo sapiens myosin light chain kina... 95 1e-19
X90569-1|CAA62189.1| 7962|Homo sapiens elastic titin protein. 94 4e-19
AJ277892-2|CAD12456.1|30017|Homo sapiens Titin protein. 94 4e-19
AM231061-1|CAJ76912.1| 1960|Homo sapiens obscurin isoform B prot... 92 1e-18
AL670729-4|CAH71670.2| 2582|Homo sapiens obscurin, cytoskeletal ... 92 1e-18
AL353593-4|CAM27610.1| 2582|Homo sapiens obscurin, cytoskeletal ... 92 1e-18
AJ314908-1|CAC85755.1| 1020|Homo sapiens obscurin protein. 92 1e-18
AB046859-1|BAB13465.2| 2584|Homo sapiens KIAA1639 protein protein. 92 1e-18
DQ533874-1|ABF83431.1| 1378|Homo sapiens ROBO2 isoform b protein. 90 5e-18
DQ533873-1|ABF83430.1| 1394|Homo sapiens ROBO2 isoform a protein. 90 5e-18
AB046788-1|BAB13394.1| 1380|Homo sapiens KIAA1568 protein protein. 90 5e-18
D86983-1|BAA13219.1| 1496|Homo sapiens KIAA0230 protein. 88 3e-17
BC098579-1|AAH98579.1| 722|Homo sapiens PXDN protein protein. 88 3e-17
AF200348-1|AAF06354.1| 1496|Homo sapiens melanoma-associated ant... 88 3e-17
X90568-1|CAA62188.1|26926|Homo sapiens titin protein. 87 3e-17
BC070170-1|AAH70170.1| 637|Homo sapiens TTN protein protein. 87 3e-17
BC058824-1|AAH58824.1| 558|Homo sapiens TTN protein protein. 87 3e-17
BC013396-1|AAH13396.1| 305|Homo sapiens TTN protein protein. 87 3e-17
AJ277892-3|CAD12457.1| 5604|Homo sapiens Novex-3 Titin Isoform p... 87 3e-17
AJ277892-1|CAD12455.1|26926|Homo sapiens N2B-Titin Isoform protein. 87 3e-17
AC023270-1|AAX88844.1| 5604|Homo sapiens unknown protein. 87 3e-17
X69490-1|CAA49245.1| 4650|Homo sapiens titin protein. 87 6e-17
BC115022-1|AAI15023.1| 1551|Homo sapiens ROBO1 protein protein. 85 2e-16
BC115020-1|AAI15021.1| 1606|Homo sapiens ROBO1 protein protein. 85 2e-16
BC112336-1|AAI12337.1| 1607|Homo sapiens ROBO1 protein protein. 85 2e-16
AF040990-1|AAC39575.1| 1651|Homo sapiens roundabout 1 protein. 85 2e-16
BC012102-1|AAH12102.1| 347|Homo sapiens PTPRF protein protein. 85 2e-16
AL583862-13|CAI14896.1| 347|Homo sapiens protein tyrosine phosp... 85 2e-16
BC013867-1|AAH13867.2| 510|Homo sapiens PALLD protein protein. 83 6e-16
AF151909-1|AAD34146.1| 404|Homo sapiens CGI-151 protein protein. 83 6e-16
AB023209-1|BAA76836.1| 772|Homo sapiens KIAA0992 protein protein. 83 6e-16
U72391-1|AAC51287.1| 1461|Homo sapiens neogenin protein. 83 1e-15
U61262-1|AAB17263.1| 1461|Homo sapiens neogenin protein. 83 1e-15
BC117161-1|AAI17162.1| 1461|Homo sapiens neogenin homolog 1 (chi... 83 1e-15
Y00815-1|CAA68754.1| 1897|Homo sapiens put. LAR preprotein (AA -... 82 1e-15
BC048768-1|AAH48768.1| 1898|Homo sapiens protein tyrosine phosph... 82 1e-15
BC048416-1|AAH48416.1| 353|Homo sapiens PTPRF protein protein. 82 1e-15
AL583862-12|CAI14897.1| 353|Homo sapiens protein tyrosine phosp... 82 1e-15
AL583862-10|CAI14894.1| 1907|Homo sapiens protein tyrosine phosp... 82 1e-15
AL583862-9|CAI14895.1| 1898|Homo sapiens protein tyrosine phosph... 82 1e-15
AB177857-1|BAD66835.1| 1918|Homo sapiens LAR protein. 82 1e-15
AB177856-1|BAD66834.1| 1484|Homo sapiens LAR splice variant 1 pr... 82 1e-15
AK056544-1|BAB71212.1| 1034|Homo sapiens protein ( Homo sapiens ... 82 2e-15
BC107797-1|AAI07798.1| 179|Homo sapiens TTN protein protein. 81 2e-15
AL583862-11|CAM12884.1| 262|Homo sapiens protein tyrosine phosp... 81 2e-15
AF464873-1|AAL69964.1| 1106|Homo sapiens myoneurin protein. 81 2e-15
AY509035-1|AAS91662.1| 1386|Homo sapiens roundabout-like protein... 81 3e-15
DQ234351-1|ABB29980.1| 262|Homo sapiens protein tyrosine phosph... 80 5e-15
X76132-1|CAA53735.1| 1447|Homo sapiens tumour suppressor protein. 80 7e-15
X64697-1|CAA45938.1| 3100|Homo sapiens titin protein. 80 7e-15
M32292-1|AAA35751.1| 750|Homo sapiens protein ( Human colorecta... 80 7e-15
AJ314896-1|CAC85745.1| 163|Homo sapiens obscurin protein. 79 1e-14
AY877349-1|AAX70929.1| 1463|Homo sapiens cardiac peroxidase prot... 79 2e-14
AL713647-1|CAD28458.1| 1232|Homo sapiens hypothetical protein pr... 77 5e-14
BC106713-1|AAI06714.1| 1505|Homo sapiens PTPRD protein protein. 76 8e-14
BC113118-1|AAI13119.1| 1028|Homo sapiens contactin 6 protein. 76 1e-13
AB003592-1|BAA82612.1| 1028|Homo sapiens neural adhesion molecul... 76 1e-13
BX928748-1|CAH74051.1| 5635|Homo sapiens protein ( Human DNA seq... 75 1e-13
BC106716-1|AAI06717.1| 1496|Homo sapiens PTPRD protein protein. 75 1e-13
BC104812-1|AAI04813.1| 1501|Homo sapiens protein tyrosine phosph... 75 1e-13
AL391824-1|CAI17865.1| 5635|Homo sapiens protein ( Human DNA seq... 75 1e-13
AL135797-1|CAI17871.1| 5635|Homo sapiens protein ( Human DNA seq... 75 1e-13
AL135796-1|CAI17854.1| 5635|Homo sapiens protein ( Human DNA seq... 75 1e-13
AL133553-2|CAI17858.1| 5635|Homo sapiens protein ( Human DNA seq... 75 1e-13
AL133515-1|CAI17853.1| 5635|Homo sapiens protein ( Human DNA seq... 75 1e-13
AL121996-1|CAI17844.1| 5635|Homo sapiens protein ( Human DNA seq... 75 1e-13
AL118512-1|CAI17864.1| 5635|Homo sapiens protein ( Human DNA seq... 75 1e-13
AK056336-1|BAB71154.1| 512|Homo sapiens protein ( Homo sapiens ... 75 1e-13
AB209333-1|BAD92570.1| 1560|Homo sapiens protein tyrosine phosph... 75 1e-13
U41725-1|AAD09360.1| 1502|Homo sapiens PTPsigma-(brain) protein. 75 2e-13
U40317-1|AAC50567.1| 1911|Homo sapiens PTPsigma protein. 75 2e-13
BC130619-1|AAI30620.1| 1100|Homo sapiens CNTN5 protein protein. 75 2e-13
BC039255-1|AAH39255.1| 617|Homo sapiens CNTN5 protein protein. 75 2e-13
BC036524-1|AAH36524.1| 772|Homo sapiens DCC protein protein. 75 2e-13
AF156100-1|AAK68690.1| 5636|Homo sapiens hemicentin protein. 75 2e-13
AB013803-1|BAA36580.2| 1026|Homo sapiens hNB-2s protein. 75 2e-13
AB013802-1|BAA36579.2| 1100|Homo sapiens hNB-2 protein. 75 2e-13
Z21488-1|CAA79696.1| 1018|Homo sapiens contactin protein. 75 3e-13
U07820-1|AAA67921.1| 1007|Homo sapiens h-contactin 2 precursor p... 75 3e-13
U07819-1|AAA67920.1| 1018|Homo sapiens h-contactin 1 precursor p... 75 3e-13
BC036569-1|AAH36569.1| 627|Homo sapiens CNTN1 protein protein. 75 3e-13
AK056557-1|BAB71216.1| 1252|Homo sapiens protein ( Homo sapiens ... 75 3e-13
AL834247-1|CAD38923.2| 1391|Homo sapiens hypothetical protein pr... 74 5e-13
AL832379-1|CAD91155.1| 1045|Homo sapiens hypothetical protein pr... 74 5e-13
AL832002-1|CAD89906.1| 1320|Homo sapiens hypothetical protein pr... 74 5e-13
AL512429-2|CAH73748.1| 1320|Homo sapiens sarcomeric protein myop... 74 5e-13
AL512429-1|CAH73747.1| 1045|Homo sapiens sarcomeric protein myop... 74 5e-13
AF328296-1|AAK50625.1| 1320|Homo sapiens myopalladin protein. 74 5e-13
AL834139-1|CAD38854.1| 1340|Homo sapiens hypothetical protein pr... 73 6e-13
AJ277892-5|CAD12459.1| 2154|Homo sapiens Titin Novex-1 Isoform p... 73 6e-13
AJ277892-4|CAD12458.1| 1294|Homo sapiens Titin Novex-2 Isoform p... 73 6e-13
U35234-1|AAC50299.1| 1948|Homo sapiens protein tyrosine phosphat... 73 8e-13
X68274-1|CAA48335.1| 1040|Homo sapiens TAG-1/axonin-1 precursor ... 73 1e-12
X67734-1|CAA47963.1| 1040|Homo sapiens transient axonal glycopro... 73 1e-12
BC129986-1|AAI29987.1| 1040|Homo sapiens contactin 2 (axonal) pr... 73 1e-12
BC114435-1|AAI14436.1| 1264|Homo sapiens Cdon homolog (mouse) pr... 73 1e-12
BC067107-1|AAH67107.1| 814|Homo sapiens putative neuronal cell ... 73 1e-12
BC042054-1|AAH42054.1| 814|Homo sapiens putative neuronal cell ... 73 1e-12
AL583832-3|CAI15288.1| 1040|Homo sapiens contactin 2 (axonal) pr... 73 1e-12
BC098583-1|AAH98583.1| 1287|Homo sapiens Cdon homolog (mouse) pr... 72 1e-12
BC109099-1|AAI09100.1| 773|Homo sapiens MUSK protein protein. 72 2e-12
BC109098-1|AAI09099.1| 783|Homo sapiens MUSK protein protein. 72 2e-12
AL513328-2|CAI17350.1| 867|Homo sapiens muscle, skeletal, recep... 72 2e-12
AL513328-1|CAI17349.1| 875|Homo sapiens muscle, skeletal, recep... 72 2e-12
AL157881-3|CAH69978.1| 867|Homo sapiens muscle, skeletal, recep... 72 2e-12
AL157881-2|CAH69977.1| 875|Homo sapiens muscle, skeletal, recep... 72 2e-12
AF006464-1|AAB63044.1| 869|Homo sapiens muscle specific tyrosin... 72 2e-12
AF004841-1|AAC34901.2| 1264|Homo sapiens CDO protein. 72 2e-12
AK128020-1|BAC87234.1| 595|Homo sapiens ursor. protein. 71 2e-12
AB208869-1|BAD92106.1| 1478|Homo sapiens protein tyrosine phosph... 71 3e-12
BC126171-1|AAI26172.1| 1119|Homo sapiens leucine-rich repeats an... 71 4e-12
BC126169-1|AAI26170.1| 1119|Homo sapiens leucine-rich repeats an... 71 4e-12
AY505340-1|AAR98629.1| 1119|Homo sapiens leucine-rich and immuno... 71 4e-12
AY358295-1|AAQ88662.1| 1059|Homo sapiens SAPS287 protein. 71 4e-12
AY358288-1|AAQ88655.1| 1119|Homo sapiens SAPS287 protein. 71 4e-12
AK074921-1|BAC11295.1| 697|Homo sapiens protein ( Homo sapiens ... 71 4e-12
L38929-1|AAC41749.1| 1912|Homo sapiens protein tyrosine phosphat... 70 6e-12
BC106715-1|AAI06716.1| 1505|Homo sapiens PTPRD protein protein. 70 6e-12
BC106714-1|AAI06715.1| 1506|Homo sapiens PTPRD protein protein. 70 6e-12
BC005376-1|AAH05376.1| 498|Homo sapiens myotilin protein. 70 6e-12
AL590397-1|CAH73128.2| 1912|Homo sapiens protein tyrosine phosph... 70 6e-12
AL583805-2|CAH70443.2| 1912|Homo sapiens protein tyrosine phosph... 70 6e-12
AL445926-1|CAH73847.2| 1912|Homo sapiens protein tyrosine phosph... 70 6e-12
AL391822-6|CAI14661.1| 1157|Homo sapiens neurofascin homolog (ch... 70 6e-12
AL391822-3|CAI14658.1| 1174|Homo sapiens neurofascin homolog (ch... 70 6e-12
AL356584-1|CAI16146.2| 1912|Homo sapiens protein tyrosine phosph... 70 6e-12
AL137125-1|CAH70912.2| 1912|Homo sapiens protein tyrosine phosph... 70 6e-12
AF144477-1|AAD44754.1| 498|Homo sapiens myotilin protein. 70 6e-12
AF133820-1|AAD29051.2| 498|Homo sapiens titin-like protein prot... 70 6e-12
AB211400-1|BAE79816.1| 1912|Homo sapiens protein tyrosine phosph... 70 6e-12
AB177861-1|BAD66839.1| 836|Homo sapiens KIAA0756 splice variant... 70 6e-12
AB018299-1|BAA34476.3| 1222|Homo sapiens KIAA0756 protein protein. 70 6e-12
AY603755-1|AAT80901.1| 3094|Homo sapiens striated muscle prefere... 70 7e-12
AB037718-1|BAA92535.1| 2242|Homo sapiens KIAA1297 protein protein. 70 7e-12
X90870-1|CAA62378.1| 458|Homo sapiens myosin-light-chain kinase... 69 1e-11
X85337-1|CAA59685.1| 991|Homo sapiens myosin light chain kinase... 69 1e-11
BC113458-1|AAI13459.1| 166|Homo sapiens MYLK protein protein. 69 1e-11
BC113456-1|AAI13457.1| 167|Homo sapiens MYLK protein protein. 69 1e-11
BC107783-1|AAI07784.1| 227|Homo sapiens MYLK protein protein. 69 1e-11
BC100763-1|AAI00764.2| 153|Homo sapiens myosin, light chain kin... 69 1e-11
BC100762-1|AAI00763.2| 154|Homo sapiens myosin, light chain kin... 69 1e-11
BC100761-1|AAI00762.2| 154|Homo sapiens myosin, light chain kin... 69 1e-11
BC064420-1|AAH64420.2| 153|Homo sapiens myosin, light chain kin... 69 1e-11
BC018128-1|AAH18128.1| 820|Homo sapiens fibroblast growth facto... 69 1e-11
BC017811-1|AAH17811.1| 236|Homo sapiens MYLK protein protein. 69 1e-11
AF096775-1|AAD54019.1| 154|Homo sapiens kinase-related protein ... 69 1e-11
AF096774-1|AAD54018.1| 153|Homo sapiens kinase-related protein ... 69 1e-11
AF096773-1|AAD54017.1| 154|Homo sapiens kinase-related protein ... 69 1e-11
AF096771-2|AAD51381.1| 153|Homo sapiens kinase related protein ... 69 1e-11
AF096771-1|AAD51380.1| 300|Homo sapiens smooth muscle/nonmuscle... 69 1e-11
AB037663-1|BAB21504.1| 992|Homo sapiens myosin light chain kina... 69 1e-11
BC117674-1|AAI17675.2| 1240|Homo sapiens NFASC protein protein. 69 1e-11
BC008124-1|AAH08124.2| 294|Homo sapiens NFASC protein protein. 69 1e-11
AY730707-1|AAU44786.1| 1093|Homo sapiens leucine-rich repeat pro... 69 1e-11
AL391822-8|CAI14664.1| 1040|Homo sapiens neurofascin homolog (ch... 69 1e-11
AL391822-7|CAI14662.1| 1165|Homo sapiens neurofascin homolog (ch... 69 1e-11
AL391822-5|CAI14659.1| 1240|Homo sapiens neurofascin homolog (ch... 69 1e-11
AL391822-4|CAI14660.1| 1347|Homo sapiens neurofascin homolog (ch... 69 1e-11
AL391822-2|CAI14657.1| 619|Homo sapiens neurofascin homolog (ch... 69 1e-11
AL117666-1|CAB56036.1| 483|Homo sapiens hypothetical protein pr... 69 1e-11
AJ306906-1|CAC37630.1| 2673|Homo sapiens fibulin-6 protein. 69 1e-11
AF381545-1|AAK62357.1| 1093|Homo sapiens membrane glycoprotein L... 69 1e-11
AC005338-1|AAC27825.1| 475|Homo sapiens PTPsigma, partial CDS p... 69 1e-11
AB050468-1|BAB40659.1| 1094|Homo sapiens membrane glycoprotein L... 69 1e-11
M63888-1|AAA35959.1| 662|Homo sapiens heparin-binding growth fa... 69 2e-11
M63887-1|AAA35958.1| 822|Homo sapiens heparin-binding growth fa... 69 2e-11
M34641-1|AAA35835.1| 820|Homo sapiens protein ( Human fibroblas... 69 2e-11
M34186-1|AAA35837.1| 731|Homo sapiens protein ( Human fibroblas... 69 2e-11
AF058332-2|AAD22604.1| 926|Homo sapiens myocardium-specific tit... 69 2e-11
AF058332-1|AAD22603.1| 1019|Homo sapiens titin protein. 69 2e-11
X66945-1|CAA47375.1| 822|Homo sapiens fibroblast growth factor ... 68 2e-11
X62515-1|CAA44373.1| 4393|Homo sapiens Human basement membrane h... 68 2e-11
X57122-1|CAA40404.1| 731|Homo sapiens Fibroblast Growth Factor ... 68 2e-11
X57121-1|CAA40403.1| 822|Homo sapiens Fibroblast Growth Factor ... 68 2e-11
X57120-1|CAA40402.1| 820|Homo sapiens Fibroblast Growth Factor ... 68 2e-11
X57119-1|CAA40401.1| 733|Homo sapiens Fibroblast Growth Factor ... 68 2e-11
X52833-1|CAA37015.1| 822|Homo sapiens protein ( Human flg mRNA ... 68 2e-11
X51803-1|CAA36101.1| 822|Homo sapiens protein ( Human mRNA for ... 68 2e-11
U75330-1|AAB80803.1| 837|Homo sapiens neural cell adhesion prot... 68 2e-11
M85289-1|AAA52700.1| 4391|Homo sapiens heparan sulfate proteogly... 68 2e-11
M60485-1|AAA35840.1| 820|Homo sapiens fibroblast growth factor ... 68 2e-11
M37722-1|AAA75007.1| 731|Homo sapiens basic fibroblast growth f... 68 2e-11
M34185-1|AAA35836.1| 733|Homo sapiens protein ( Human fibroblas... 68 2e-11
BC091494-1|AAH91494.1| 731|Homo sapiens fibroblast growth facto... 68 2e-11
BC052946-1|AAH52946.1| 837|Homo sapiens neural cell adhesion mo... 68 2e-11
BC015035-1|AAH15035.1| 820|Homo sapiens FGFR1 protein protein. 68 2e-11
AY585209-1|AAS79322.1| 822|Homo sapiens fibroblast growth facto... 68 2e-11
AL590556-2|CAH71870.1| 4391|Homo sapiens heparan sulfate proteog... 68 2e-11
AL590103-2|CAI12125.1| 4391|Homo sapiens heparan sulfate proteog... 68 2e-11
AL445795-1|CAC18534.1| 4370|Homo sapiens heparan sulfate proteog... 68 2e-11
AB208919-1|BAD92156.1| 814|Homo sapiens fibroblast growth facto... 68 2e-11
AB209851-1|BAD93088.1| 2331|Homo sapiens Basement membrane-speci... 68 3e-11
BC045734-1|AAH45734.1| 442|Homo sapiens IGSF10 protein protein. 67 4e-11
BC031063-1|AAH31063.1| 602|Homo sapiens IGSF10 protein protein. 67 4e-11
AY273815-1|AAQ16156.1| 2623|Homo sapiens bone specific CMF608 pr... 67 4e-11
AK098838-1|BAC05429.1| 399|Homo sapiens protein ( Homo sapiens ... 67 4e-11
AK093583-1|BAC04201.1| 329|Homo sapiens protein ( Homo sapiens ... 67 4e-11
AK093069-1|BAC04042.1| 650|Homo sapiens protein ( Homo sapiens ... 67 4e-11
BC036769-1|AAH36769.1| 504|Homo sapiens fibroblast growth facto... 67 5e-11
AY358303-1|AAQ88670.1| 504|Homo sapiens FGFRL1 protein. 67 5e-11
AK222718-1|BAD96438.1| 820|Homo sapiens fibroblast growth facto... 67 5e-11
AK172829-1|BAD18794.1| 440|Homo sapiens protein ( Homo sapiens ... 67 5e-11
AJ277437-1|CAC14171.1| 504|Homo sapiens FGFR-like protein protein. 67 5e-11
AF312678-1|AAK15273.1| 497|Homo sapiens FGF homologous factor r... 67 5e-11
AF279689-1|AAK26742.1| 504|Homo sapiens fibroblast growth facto... 67 5e-11
AF069604-1|AAD15924.1| 560|Homo sapiens myosin light chain kina... 66 7e-11
AK130921-1|BAC85460.1| 572|Homo sapiens protein ( Homo sapiens ... 66 9e-11
AK074780-1|BAC11205.1| 570|Homo sapiens protein ( Homo sapiens ... 66 1e-10
AB040947-1|BAA96038.1| 1598|Homo sapiens KIAA1514 protein protein. 66 1e-10
BC117370-1|AAI17371.1| 1065|Homo sapiens leucine-rich repeats an... 65 2e-10
BC117368-1|AAI17369.1| 1065|Homo sapiens leucine-rich repeats an... 65 2e-10
AY630258-1|AAU05741.1| 1150|Homo sapiens shen-dan protein. 65 2e-10
AL357055-1|CAH73254.1| 1065|Homo sapiens leucine-rich repeats an... 65 2e-10
AF202063-1|AAF27432.1| 762|Homo sapiens fibroblast growth facto... 65 2e-10
AB018349-1|BAA34526.2| 1073|Homo sapiens KIAA0806 protein protein. 65 2e-10
X57205-1|CAA40490.1| 802|Homo sapiens fibroblast growth factor ... 64 3e-10
BX537391-1|CAD97633.1| 143|Homo sapiens hypothetical protein pr... 64 3e-10
AY310398-1|AAP75619.1| 2213|Homo sapiens sidekick-like protein 1... 64 3e-10
AY358328-1|AAQ88694.1| 1115|Homo sapiens BOC protein. 64 5e-10
AY027658-1|AAK14795.1| 1114|Homo sapiens brother of CDO protein. 64 5e-10
AK090455-1|BAC03436.1| 931|Homo sapiens FLJ00376 protein protein. 64 5e-10
BX538319-1|CAD98093.1| 1290|Homo sapiens hypothetical protein pr... 63 8e-10
Y13901-1|CAA74200.1| 802|Homo sapiens fibroblast growth factor ... 62 1e-09
X61656-1|CAA43837.1| 1354|Homo sapiens membrane protein protein. 62 1e-09
L04947-1|AAA59459.1| 1354|Homo sapiens receptor tyrosine kinase ... 62 1e-09
L03840-1|AAB59389.1| 802|Homo sapiens fibroblast growth factor ... 62 1e-09
EF571596-1|ABQ01235.1| 802|Homo sapiens fibroblast growth facto... 62 1e-09
EF063638-1|ABO42328.1| 1896|Homo sapiens obscurin-like 1 isoform... 62 1e-09
EF063637-1|ABO42327.1| 1544|Homo sapiens obscurin-like 1 isoform... 62 1e-09
BC131822-1|AAI31823.1| 1356|Homo sapiens kinase insert domain re... 62 1e-09
BC011847-1|AAH11847.1| 802|Homo sapiens fibroblast growth facto... 62 1e-09
BC007201-1|AAH07201.1| 1044|Homo sapiens OBSL1 protein protein. 62 1e-09
AJ314906-1|CAC85753.1| 1040|Homo sapiens obscurin protein. 62 1e-09
AF487555-1|AAM13666.1| 802|Homo sapiens fibroblast growth facto... 62 1e-09
AF245505-1|AAF86402.1| 2828|Homo sapiens adlican protein. 62 1e-09
AF063658-1|AAC16450.1| 1356|Homo sapiens vascular endothelial gr... 62 1e-09
AF035121-1|AAB88005.1| 1356|Homo sapiens KDR/flk-1 protein protein. 62 1e-09
AB209901-1|BAD93138.1| 1451|Homo sapiens kinase insert domain re... 62 1e-09
AB209631-1|BAD92868.1| 1034|Homo sapiens Fibroblast growth facto... 62 1e-09
BC115736-1|AAI15737.1| 1192|Homo sapiens NRCAM protein protein. 62 1e-09
BC114570-1|AAI14571.1| 1180|Homo sapiens NRCAM protein protein. 62 1e-09
BC098401-1|AAH98401.1| 771|Homo sapiens NRCAM protein protein. 62 1e-09
AJ001057-1|CAA04507.1| 1299|Homo sapiens NrCAM protein protein. 62 1e-09
AB002341-1|BAA20801.2| 1187|Homo sapiens KIAA0343 protein. 62 1e-09
BX538010-1|CAD97960.1| 1183|Homo sapiens hypothetical protein pr... 62 2e-09
AF172277-2|AAF22283.1| 1236|Homo sapiens NgCAM-related related c... 62 2e-09
AF172277-1|AAF22282.1| 1308|Homo sapiens NgCAM-related related c... 62 2e-09
X16841-1|CAA34739.1| 761|Homo sapiens protein ( Human mRNA for ... 61 3e-09
S71824-1|AAB31836.1| 848|Homo sapiens N-CAM protein. 61 3e-09
BC128390-1|AAI28391.1| 1682|Homo sapiens ADAMTSL3 protein protein. 61 3e-09
BC128389-1|AAI28390.1| 1691|Homo sapiens ADAMTS-like 3 protein. 61 3e-09
BC026119-1|AAH26119.1| 697|Homo sapiens contactin 4 protein. 61 3e-09
AY090737-1|AAM00025.1| 1026|Homo sapiens contactin 4 protein. 61 3e-09
AF549455-1|AAP05786.1| 1026|Homo sapiens BIG-2 protein. 61 3e-09
AF491813-1|AAM09558.1| 2113|Homo sapiens Down syndrome cell adhe... 61 3e-09
AF334384-1|AAL57166.1| 2053|Homo sapiens Down syndrome cell adhe... 61 3e-09
AF304305-1|AAN32614.1| 1842|Homo sapiens Down syndrome cell adhe... 61 3e-09
AB209443-1|BAD92680.1| 807|Homo sapiens Neural cell adhesion mo... 61 3e-09
AB033059-1|BAA86547.1| 1023|Homo sapiens KIAA1233 protein protein. 61 3e-09
AB032958-1|BAA86446.2| 2092|Homo sapiens KIAA1132 protein protein. 61 3e-09
AF304304-1|AAN32613.1| 2053|Homo sapiens Down syndrome cell adhe... 61 3e-09
AB209412-1|BAD92649.1| 1130|Homo sapiens neogenin homolog 1 vari... 60 6e-09
AB040929-1|BAA96020.1| 920|Homo sapiens KIAA1496 protein protein. 60 6e-09
M64347-1|AAA58470.1| 731|Homo sapiens fgflr protein. 60 8e-09
M58051-1|AAA52450.1| 806|Homo sapiens fibroblast growth factor ... 60 8e-09
AY768549-1|AAU89726.1| 806|Homo sapiens fibroblast growth facto... 60 8e-09
AL163282-1|CAB90436.1| 812|Homo sapiens human CHD2-52 down synd... 60 8e-09
AF487554-2|AAM22078.1| 769|Homo sapiens fibroblast growth facto... 60 8e-09
AF217525-1|AAF27525.1| 2012|Homo sapiens Down syndrome cell adhe... 60 8e-09
AF023450-1|AAC17967.1| 1571|Homo sapiens Down syndrome cell adhe... 60 8e-09
AF023449-1|AAC17966.1| 1896|Homo sapiens Down syndrome cell adhe... 60 8e-09
AB209441-1|BAD92678.1| 879|Homo sapiens fibroblast growth facto... 60 8e-09
AB209136-1|BAD92373.1| 2023|Homo sapiens Down syndrome cell adhe... 60 8e-09
EF506611-1|ABP88252.1| 1248|Homo sapiens non-neural L1CAM protein. 59 1e-08
M29273-1|AAA59545.1| 626|Homo sapiens MAG protein. 59 1e-08
BC093045-1|AAH93045.1| 582|Homo sapiens myelin associated glyco... 59 1e-08
BC053347-1|AAH53347.1| 626|Homo sapiens myelin associated glyco... 59 1e-08
BC047244-1|AAH47244.1| 858|Homo sapiens neural cell adhesion mo... 59 1e-08
AK223562-1|BAD97282.1| 626|Homo sapiens myelin associated glyco... 59 1e-08
AK222649-1|BAD96369.1| 626|Homo sapiens myelin associated glyco... 59 1e-08
AC002132-1|AAB58805.1| 626|Homo sapiens MAG protein. 59 1e-08
AB209170-1|BAD92407.1| 661|Homo sapiens myelin associated glyco... 59 1e-08
Z29373-1|CAA82564.1| 1257|Homo sapiens neural cell adhesion mole... 58 2e-08
U63041-1|AAB04558.1| 848|Homo sapiens neural cell adhesion mole... 58 2e-08
U57099-1|AAC50599.1| 113|Homo sapiens APEG-1 protein protein. 58 2e-08
M77640-1|AAC14352.1| 1257|Homo sapiens L1 cell adhesion molecule... 58 2e-08
M74387-1|AAA59476.1| 1253|Homo sapiens cell adhesion molecule L1... 58 2e-08
DQ173642-2|ABC25979.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
DQ173641-2|ABC25974.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
DQ173640-2|ABC25969.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
DQ173639-2|ABC25964.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
DQ173638-2|ABC25959.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
DQ173637-2|ABC25954.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
DQ173636-2|ABC25949.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
DQ173635-2|ABC25944.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
DQ173634-2|ABC25939.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
DQ173633-2|ABC25934.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
DQ173632-2|ABC25929.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
DQ173631-2|ABC25924.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
DQ173630-2|ABC25919.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
DQ173629-2|ABC25914.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
DQ173628-2|ABC25909.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
DQ173627-2|ABC25904.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
DQ173626-2|ABC25899.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
DQ173625-2|ABC25894.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
DQ173624-2|ABC25889.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
DQ173623-2|ABC25884.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
DQ173622-2|ABC25879.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
DQ173621-2|ABC25874.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
DQ173620-2|ABC25869.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
DQ173619-2|ABC25864.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
DQ173618-2|ABC25859.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
DQ173617-2|ABC25854.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
DQ173616-2|ABC25849.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
DQ173615-2|ABC25844.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
DQ173614-2|ABC25839.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
DQ173613-2|ABC25834.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
DQ173612-2|ABC25829.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
DQ173611-2|ABC25824.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
DQ173610-2|ABC25819.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
DQ173609-2|ABC25814.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
DQ173608-2|ABC25809.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
DQ173607-2|ABC25804.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
DQ173606-2|ABC25799.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
DQ173605-2|ABC25794.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
DQ173604-2|ABC25789.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
DQ173603-2|ABC25784.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
DQ173602-2|ABC25779.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
DQ173601-2|ABC25774.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
DQ173600-2|ABC25769.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
DQ173599-2|ABC25764.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
DQ173598-2|ABC25759.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
DQ173597-2|ABC25755.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
DQ173596-2|ABC25750.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
DQ173595-2|ABC25745.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
DQ173594-2|ABC25740.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
DQ173593-2|ABC25735.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
DQ173592-2|ABC25730.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
DQ173589-1|ABB58724.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
CR542201-1|CAG46998.1| 113|Homo sapiens APEG1 protein. 58 2e-08
BC126229-1|AAI26230.1| 1257|Homo sapiens L1 cell adhesion molecu... 58 2e-08
BC006346-1|AAH06346.1| 113|Homo sapiens SPEG protein protein. 58 2e-08
AY167726-1|AAO17629.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
AY167725-1|AAO17628.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
AY167724-1|AAO17627.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
AY167723-1|AAO17626.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
AY167722-1|AAO17625.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
AY167721-1|AAO17624.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
AY167720-1|AAO17623.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
AY167719-1|AAO17622.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
AY167718-1|AAO17621.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
AY167717-1|AAO17620.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
AY167716-1|AAO17619.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
AY167715-1|AAO17618.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
AY167714-1|AAO17617.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
AY167713-1|AAO17616.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
AY167712-1|AAO17615.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
AY167711-1|AAO17614.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
AY167710-1|AAO17613.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
AY167709-1|AAO17612.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
AY167708-1|AAO17611.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
AY167707-1|AAO17610.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
AY167706-1|AAO17609.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
AY167705-1|AAO17608.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
AY167704-1|AAO17607.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
AY167703-1|AAO17606.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
AY167702-1|AAO17605.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
AY167701-1|AAO17604.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
AY167700-1|AAO17603.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
AY167699-1|AAO17602.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
AY167698-1|AAO17601.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
AY167697-1|AAO17600.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
AY167696-1|AAO17599.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
AY167695-1|AAO17598.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
AY167694-1|AAO17597.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
AY167693-1|AAO17596.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
AY167692-1|AAO17595.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
AY167691-1|AAO17594.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
AY167690-1|AAO17593.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
AY167689-1|AAO17592.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
AY167688-1|AAO17591.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
AY167687-1|AAO17590.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
AY167686-1|AAO17589.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
AY167685-1|AAO17588.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
AY167684-1|AAO17587.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
AY167683-1|AAO17586.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
AY167682-1|AAO17585.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
AY167681-1|AAO17584.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
AY167680-1|AAO17583.1| 534|Homo sapiens L1 cell adhesion molecu... 58 2e-08
AK128689-1|BAC87572.1| 175|Homo sapiens protein ( Homo sapiens ... 58 2e-08
AK126500-1|BAC86568.1| 170|Homo sapiens protein ( Homo sapiens ... 58 2e-08
AC053503-3|AAY15052.1| 113|Homo sapiens unknown protein. 58 2e-08
AB102653-1|BAC81122.1| 1255|Homo sapiens L1 cell adhesion molecu... 58 2e-08
U42390-1|AAC34245.1| 2861|Homo sapiens Trio protein. 58 3e-08
BC036502-1|AAH36502.1| 847|Homo sapiens follistatin-like 5 prot... 58 3e-08
AK131423-1|BAD18570.1| 596|Homo sapiens protein ( Homo sapiens ... 58 3e-08
AF091395-1|AAC43042.1| 3038|Homo sapiens Trio isoform protein. 58 3e-08
AF040991-1|AAC39576.1| 285|Homo sapiens roundabout 2 protein. 58 3e-08
AB033089-1|BAA86577.1| 850|Homo sapiens KIAA1263 protein protein. 58 3e-08
AB014557-1|BAA31632.2| 1237|Homo sapiens KIAA0657 protein protein. 58 3e-08
BC104918-1|AAI04919.1| 1208|Homo sapiens CHL1 protein protein. 57 6e-08
AF289030-1|AAL56711.1| 1746|Homo sapiens Down syndrome cell adhe... 57 6e-08
AF002246-1|AAB60937.1| 1224|Homo sapiens neural cell adhesion mo... 57 6e-08
AB209329-1|BAD92566.1| 1210|Homo sapiens Neural cell adhesion mo... 57 6e-08
U55258-1|AAC50765.1| 1299|Homo sapiens hBRAVO/Nr-CAM precursor p... 56 7e-08
AK222680-1|BAD96400.1| 626|Homo sapiens myelin associated glyco... 56 7e-08
AL590103-6|CAI12129.1| 188|Homo sapiens heparan sulfate proteog... 56 1e-07
AL137695-1|CAB70877.1| 773|Homo sapiens hypothetical protein pr... 56 1e-07
AK128160-1|BAC87305.1| 632|Homo sapiens protein ( Homo sapiens ... 56 1e-07
AL360004-4|CAI16954.2| 746|Homo sapiens novel protein similar t... 56 1e-07
X73113-1|CAA51544.1| 1142|Homo sapiens fast MyBP-C protein. 55 2e-07
BC130536-1|AAI30537.1| 1141|Homo sapiens myosin binding protein ... 55 2e-07
BC071561-1|AAH71561.1| 1070|Homo sapiens LRIG1 protein protein. 55 2e-07
BC014276-1|AAH14276.2| 417|Homo sapiens LRIG1 protein protein. 55 2e-07
BC013955-1|AAH13955.2| 365|Homo sapiens FGFRL1 protein protein. 55 2e-07
AC007567-1|AAS07434.1| 383|Homo sapiens unknown protein. 55 2e-07
AC005525-1|AAC32740.1| 381|Homo sapiens F22162_1 protein. 55 2e-07
U41901-1|AAC50569.1| 338|Homo sapiens LAMP protein. 54 3e-07
DQ464902-1|ABE97925.1| 675|Homo sapiens nexilin protein. 54 3e-07
BC114445-1|AAI14446.1| 567|Homo sapiens NEXN protein protein. 54 3e-07
BC114444-1|AAI14445.1| 567|Homo sapiens NEXN protein protein. 54 3e-07
BC114334-1|AAI14335.2| 280|Homo sapiens NRG2 protein protein. 54 3e-07
BC114333-1|AAI14334.2| 280|Homo sapiens NRG2 protein protein. 54 3e-07
BC111395-1|AAI11396.1| 554|Homo sapiens NEXN protein protein. 54 3e-07
BC103984-1|AAI03985.2| 280|Homo sapiens NRG2 protein protein. 54 3e-07
BC103983-1|AAI03984.2| 280|Homo sapiens NRG2 protein protein. 54 3e-07
BC033803-1|AAH33803.1| 338|Homo sapiens limbic system-associate... 54 3e-07
AK057954-1|BAB71622.1| 505|Homo sapiens protein ( Homo sapiens ... 54 3e-07
AF119162-4|AAF28849.1| 844|Homo sapiens neuregulin 2 isoform 2 ... 54 3e-07
AF119162-3|AAF28851.1| 852|Homo sapiens neuregulin 2 isoform 4 ... 54 3e-07
AF119162-2|AAF28848.1| 850|Homo sapiens neuregulin 2 isoform 1 ... 54 3e-07
AF119162-1|AAF28850.1| 858|Homo sapiens neuregulin 2 isoform 3 ... 54 3e-07
AF119158-1|AAF28852.1| 426|Homo sapiens neuregulin 2 isoform 5 ... 54 3e-07
AF119157-1|AAF28853.1| 422|Homo sapiens neuregulin 2 isoform 6 ... 54 3e-07
AF114264-1|AAD29607.1| 448|Homo sapiens unknown protein. 54 3e-07
AB052622-1|BAB86306.1| 1250|Homo sapiens hDDM36 protein. 54 3e-07
AB005060-1|BAA23417.1| 850|Homo sapiens NTAK protein. 54 3e-07
Z71929-1|CAA96492.1| 821|Homo sapiens FGFR2 protein. 54 4e-07
X52832-1|CAA37014.1| 821|Homo sapiens protein ( Human bek mRNA ... 54 4e-07
U40271-1|AAC50484.2| 1070|Homo sapiens transmembrane receptor pr... 54 4e-07
M87770-1|AAA59470.1| 821|Homo sapiens fibroblast growth factor ... 54 4e-07
DQ493927-1|ABE96832.1| 785|Homo sapiens fibroblast growth facto... 54 4e-07
DQ248309-1|ABB55264.1| 851|Homo sapiens rhabdomyosarcoma antige... 54 4e-07
BX537998-1|CAD97954.1| 1263|Homo sapiens hypothetical protein pr... 54 4e-07
BC071557-1|AAH71557.1| 1070|Homo sapiens PTK7 protein tyrosine k... 54 4e-07
BC039243-1|AAH39243.2| 704|Homo sapiens FGFR2 protein protein. 54 4e-07
BC029119-1|AAH29119.1| 364|Homo sapiens NCAM1 protein protein. 54 4e-07
AL591423-1|CAM13086.1| 1263|Homo sapiens chromosome 9 open readi... 54 4e-07
AL355385-4|CAI13783.1| 1070|Homo sapiens PTK7 protein tyrosine k... 54 4e-07
AL353895-2|CAM20931.1| 1263|Homo sapiens chromosome 9 open readi... 54 4e-07
AL158150-4|CAM14352.1| 1263|Homo sapiens chromosome 9 open readi... 54 4e-07
AK092284-1|BAC03850.1| 885|Homo sapiens protein ( Homo sapiens ... 54 4e-07
AF531872-1|AAN04866.1| 816|Homo sapiens transmembrane receptor ... 54 4e-07
AF531871-1|AAN04865.1| 1014|Homo sapiens transmembrane receptor ... 54 4e-07
AF531868-1|AAN04862.1| 1070|Homo sapiens transmembrane receptor ... 54 4e-07
AF447176-1|AAL39062.1| 1070|Homo sapiens protein tyrosine kinase... 54 4e-07
AF360695-4|AAK94208.1| 766|Homo sapiens keratinocyte growth fac... 54 4e-07
AF360695-3|AAK94209.1| 785|Homo sapiens keratinocyte growth fac... 54 4e-07
AF360695-2|AAK94205.1| 819|Homo sapiens keratinocyte growth fac... 54 4e-07
AB209350-1|BAD92587.1| 773|Homo sapiens PTK7 protein tyrosine k... 54 4e-07
M34188-1|AAA35839.1| 300|Homo sapiens protein ( Human fibroblas... 54 5e-07
M34187-1|AAA35838.1| 302|Homo sapiens protein ( Human fibroblas... 54 5e-07
AK223126-1|BAD96846.1| 300|Homo sapiens fibroblast growth facto... 54 5e-07
AF487554-1|AAM22079.1| 771|Homo sapiens fibroblast growth facto... 54 5e-07
Y00665-1|CAA68679.1| 622|Homo sapiens tyrosine kinase protein. 53 7e-07
AY211921-1|AAO65174.1| 294|Homo sapiens sarcoma antigen NY-SAR-... 53 7e-07
AL513328-3|CAI17351.1| 116|Homo sapiens muscle, skeletal, recep... 53 7e-07
AK096458-1|BAC04796.1| 410|Homo sapiens protein ( Homo sapiens ... 53 7e-07
X75958-1|CAA53571.1| 477|Homo sapiens protein-tyrosine kinase p... 53 9e-07
U12140-1|AAC51371.1| 822|Homo sapiens tyrosine kinase receptor ... 53 9e-07
S76474-1|AAB33110.1| 477|Homo sapiens trkB protein. 53 9e-07
S76473-1|AAB33109.1| 822|Homo sapiens trkB protein. 53 9e-07
BC113963-1|AAI13964.1| 262|Homo sapiens CADM4 protein protein. 53 9e-07
BC066363-1|AAH66363.1| 1805|Homo sapiens SDK2 protein protein. 53 9e-07
BC031835-1|AAH31835.1| 477|Homo sapiens neurotrophic tyrosine k... 53 9e-07
AL596132-4|CAH72315.1| 822|Homo sapiens neurotrophic tyrosine k... 53 9e-07
AL596132-3|CAH72316.1| 838|Homo sapiens neurotrophic tyrosine k... 53 9e-07
AL596132-2|CAH72313.1| 537|Homo sapiens neurotrophic tyrosine k... 53 9e-07
AL596132-1|CAH72314.1| 553|Homo sapiens neurotrophic tyrosine k... 53 9e-07
AL445532-2|CAH71817.1| 822|Homo sapiens neurotrophic tyrosine k... 53 9e-07
AL445532-1|CAH71816.1| 838|Homo sapiens neurotrophic tyrosine k... 53 9e-07
AL390777-5|CAH72197.1| 477|Homo sapiens neurotrophic tyrosine k... 53 9e-07
AL390777-4|CAH72196.1| 822|Homo sapiens neurotrophic tyrosine k... 53 9e-07
AL390777-3|CAH72195.1| 838|Homo sapiens neurotrophic tyrosine k... 53 9e-07
AL390777-2|CAH72193.1| 553|Homo sapiens neurotrophic tyrosine k... 53 9e-07
AL390777-1|CAH72194.1| 537|Homo sapiens neurotrophic tyrosine k... 53 9e-07
AF508964-1|AAM77876.1| 477|Homo sapiens protein tyrosine kinase... 53 9e-07
AF410901-1|AAL67967.1| 553|Homo sapiens neurotrophin receptor t... 53 9e-07
AF410900-1|AAL67966.1| 537|Homo sapiens neurotrophin receptor t... 53 9e-07
AF410899-1|AAL67965.1| 838|Homo sapiens neurotrophin receptor t... 53 9e-07
>AL670729-3|CAH71673.1| 6620|Homo sapiens obscurin, cytoskeletal
calmodulin and titin-interacting RhoGEF protein.
Length = 6620
Score = 96.3 bits (229), Expect = 7e-20
Identities = 67/221 (30%), Positives = 93/221 (42%), Gaps = 14/221 (6%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G CQ+ GNP P + W + + A F + D RL I + D G Y C
Sbjct: 24 GKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTILDLALGDSGQYVCR 83
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A N +G+A + L V + + AP F P + V EG TF+C V G+P P
Sbjct: 84 ARNAIGEAFAAVGLQV----DAEAACAEQAPHFLLRPTSIRVREGSEATFRCRVGGSPRP 139
Query: 126 WASWDKDGSII--TPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
SW KDG + R+ V+E E L I D G Y + EN LG A A+A
Sbjct: 140 AVSWSKDGRRLGEPDGPRVRVEELGE-ASALRIRAARPRDGGTYEVRAENPLGAASAAAA 198
Query: 184 L-------EVITRSGKFYGGLRAYSASPRKCLSYRRRPSTP 217
L + +R G L A+ R+ + P++P
Sbjct: 199 LVVDSDAADTASRPGTSTAALLAHLQRRREAMRAEGAPASP 239
Score = 92.3 bits (219), Expect = 1e-18
Identities = 56/183 (30%), Positives = 86/183 (46%), Gaps = 13/183 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIR-DCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
G+TV+ C+VTG P P I W+ + ++ D DG+ L + +T D G Y C
Sbjct: 6028 GETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQYMC 6087
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
A++ G + ++V Q+ P F EGE+ F C ++G P
Sbjct: 6088 FAASAAGNCSTLGKILV-----------QVPPRFVNKVRASPFVEGEDAQFTCTIEGAPY 6136
Query: 125 PWASWDKDGSIITPSARI-TVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
P W KDG+++T + T+ E + +L I S ED+G+Y + N LG A ASA
Sbjct: 6137 PQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAE 6196
Query: 184 LEV 186
L +
Sbjct: 6197 LRI 6199
Score = 62.5 bits (145), Expect = 1e-09
Identities = 32/92 (34%), Positives = 45/92 (48%)
Query: 95 APTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRIL 154
AP F T N+ V++G V+F C V G P P W KDG ++ + E ++ L
Sbjct: 5125 APVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQL 5184
Query: 155 EIDEVSIEDVGIYRITVENELGRAEASARLEV 186
I V D+G+YR EN +G + A L V
Sbjct: 5185 IITAVVPADMGVYRCLAENSMGVSSTKAELRV 5216
Score = 62.1 bits (144), Expect = 1e-09
Identities = 32/100 (32%), Positives = 51/100 (51%), Gaps = 1/100 (1%)
Query: 87 LSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKE 146
+ P AP F T P VV G++ T C + GNP+P SW+KD + AR + +
Sbjct: 1 MDQPQFSGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQ 60
Query: 147 KEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
++ R+ +D +++ D G Y N +G A A+ L+V
Sbjct: 61 DGDLYRLTILD-LALGDSGQYVCRARNAIGEAFAAVGLQV 99
Score = 62.1 bits (144), Expect = 1e-09
Identities = 50/165 (30%), Positives = 74/165 (44%), Gaps = 15/165 (9%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTAR--LKIKQVTAEDEGTY 62
+G C VTG P P+ W +++ + Y+D LKI D G Y
Sbjct: 251 EGKHARLSCYVTGEPKPETVWKKDGQLVTE-GRRHVVYEDAQENFVLKILFCKQSDRGLY 309
Query: 63 TCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGN 122
TC ASN +G+ S+ +VV R+ A F + V E E+ TF C V
Sbjct: 310 TCTASNLVGQTYSSVLVVV----------REPAVPFKKRLQDLEVREKESATFLCEVP-Q 358
Query: 123 PSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIY 167
PS A+W K+ + + SA+ + E+E R L + VS +D +Y
Sbjct: 359 PSTEAAWFKEETRLWASAKYGI-EEEGTERRLTVRNVSADDDAVY 402
Score = 60.9 bits (141), Expect = 3e-09
Identities = 56/206 (27%), Positives = 82/206 (39%), Gaps = 24/206 (11%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDD-GTAR-LKIKQVTAEDEGTY 62
+G F C+V G+P P + W + + ++ G A L+I+ D GTY
Sbjct: 123 EGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGTY 182
Query: 63 TCEASNCLGKAKSNACLVV--------------------YHTRRLSSPGRQMAPTF--YT 100
A N LG A + A LVV + RR + + AP T
Sbjct: 183 EVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQRRREAMRAEGAPASPPST 242
Query: 101 YPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVS 160
V EG++ C V G P P W KDG ++T R V E + +L+I
Sbjct: 243 GTRTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCK 302
Query: 161 IEDVGIYRITVENELGRAEASARLEV 186
D G+Y T N +G+ +S + V
Sbjct: 303 QSDRGLYTCTASNLVGQTYSSVLVVV 328
Score = 60.9 bits (141), Expect = 3e-09
Identities = 50/191 (26%), Positives = 81/191 (42%), Gaps = 17/191 (8%)
Query: 10 EFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNC 69
+F+ +V G P P + WF + + A + L+I VT ED G Y SN
Sbjct: 5279 KFQLKVKGYPAPRLYWFKDGQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNA 5338
Query: 70 LGKAKSNACLVVY-----HTRRLSSPGRQMAPTFYTYPFN-KVVEEGENVTFKCAVKGNP 123
+G A S+A L+V + S Q+ P F K V++G ++TF V+G P
Sbjct: 5339 MGAAYSSARLLVRGPDEPEEKPASDVHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGRP 5398
Query: 124 SPWASW---DKDGSII-----TPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENEL 175
P W + + ++ TP + ++ + +L++ + G Y N
Sbjct: 5399 VPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLDVGR---QHQGTYTCIASNAA 5455
Query: 176 GRAEASARLEV 186
G+A SA L V
Sbjct: 5456 GQALCSASLHV 5466
Score = 52.0 bits (119), Expect = 2e-06
Identities = 28/78 (35%), Positives = 40/78 (51%), Gaps = 1/78 (1%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYD-DGTARLKIKQVTAEDEGTYT 63
DG V F+C VTG P P +RWF +++ + + + D G +L I V D G Y
Sbjct: 5139 DGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQLIITAVVPADMGVYR 5198
Query: 64 CEASNCLGKAKSNACLVV 81
C A N +G + + A L V
Sbjct: 5199 CLAENSMGVSSTKAELRV 5216
Score = 48.8 bits (111), Expect = 1e-05
Identities = 25/75 (33%), Positives = 38/75 (50%), Gaps = 2/75 (2%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFE--SSYDDGTARLKIKQVTAEDEGTY 62
+G+ +F C + G P P IRW+ ++ F+ S G L I+ + ED G Y
Sbjct: 6121 EGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLY 6180
Query: 63 TCEASNCLGKAKSNA 77
CE N LG A+++A
Sbjct: 6181 ECELVNRLGSARASA 6195
Score = 48.4 bits (110), Expect = 2e-05
Identities = 26/77 (33%), Positives = 33/77 (42%), Gaps = 1/77 (1%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFE-SSYDDGTARLKIKQVTAEDEGTYTC 64
GD + EC V D RW + D DGT L I + D G YTC
Sbjct: 4912 GDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLGDGTCSLLITGLDRADAGCYTC 4971
Query: 65 EASNCLGKAKSNACLVV 81
+ SN G+ +AC+VV
Sbjct: 4972 QVSNKFGQVTHSACVVV 4988
Score = 44.8 bits (101), Expect = 2e-04
Identities = 48/180 (26%), Positives = 80/180 (44%), Gaps = 20/180 (11%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G TV C+++ ++ W +R F+ + L + + AED G Y CE
Sbjct: 1823 GGTVTLACELSP-ACAEVVWRCGNTQLRVGKRFQMVAEGPVRSLTVLGLRAEDAGEYVCE 1881
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
+ + ++A L V R + F + V EEG TF+C V +PS
Sbjct: 1882 SRD----DHTSAQLTVSVPRVVK---------FMSGLSTVVAEEGGEATFQCVV--SPSD 1926
Query: 126 WA-SWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
A W +DG+++ PS + + + L I ++ +ED G +ITVE E + A+ R+
Sbjct: 1927 VAVVWFRDGALLQPSEKFAISQ-SGASHSLTISDLVLEDAG--QITVEAEGASSSAALRV 1983
Score = 44.4 bits (100), Expect = 3e-04
Identities = 40/163 (24%), Positives = 65/163 (39%), Gaps = 16/163 (9%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G T C+V P ++ W+ + + + T RL ++QV D G Y+CE
Sbjct: 1181 GTTAMLSCEVA-QPQTEVTWYKDGKKLSSSSKVRMEVKGCTRRLVVQQVGKADAGEYSCE 1239
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKV-VEEGENVTFKCAVKGNPS 124
A G+ V ++ P A + N+V E G + T C V
Sbjct: 1240 AG---GQR-------VSFQLHITEPKAVFAKEQLVH--NEVRTEAGASATLSCEV-AQAQ 1286
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIY 167
+W KDG ++ S+++ + E MR L + + D G Y
Sbjct: 1287 TEVTWYKDGKKLSSSSKVRI-EAAGCMRQLVVQQAGQADAGEY 1328
Score = 44.4 bits (100), Expect = 3e-04
Identities = 51/199 (25%), Positives = 84/199 (42%), Gaps = 21/199 (10%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G+ + C+ T D + W + +R A + S++ A+L I T +D G Y C
Sbjct: 3109 EGEDLTLVCE-TSTCDIPVCWTKDGKTLRGSARCQLSHEGHRAQLLITGATLQDSGRYKC 3167
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
EA G A S++ +V H R P R F + V EG T +C + +
Sbjct: 3168 EA----GGACSSS-IVRVHAR----PVR-----FQEALKDLEVLEGGAATLRCVLSSVAA 3213
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
P W +++ P + ++++ E M L + + +D G Y + G SA L
Sbjct: 3214 P-VKWCYGNNVLRPGDKYSLRQ-EGAMLELVVRNLRPQDSGRYSCS----FGDQTTSATL 3267
Query: 185 EVITRSGKFYGGLRAYSAS 203
V +F G LR A+
Sbjct: 3268 TVTALPAQFIGKLRNKEAT 3286
Score = 42.7 bits (96), Expect = 0.001
Identities = 43/185 (23%), Positives = 79/185 (42%), Gaps = 19/185 (10%)
Query: 7 DTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTAR-LKIKQVTAEDEGTYTCE 65
+ VEF C+V+ ++W ++ E + DG L++K VT ED GT +
Sbjct: 4174 EDVEFSCEVSRAGATGVQWCLQGLPLQSNEVTEVAVRDGRIHTLRLKGVTPEDAGTVSFH 4233
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
LG S+A L V R T + + EG++ +F+C +
Sbjct: 4234 ----LGNHASSAQLTV----------RAPEVTILEPLQDVQLSEGQDASFQCRLSRASGQ 4279
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
A W G + + + ++ + +L + +V++ED G TV +G + A+L+
Sbjct: 4280 EARWALGGVPLQANEMNDITVEQGTLHLLTLHKVTLEDAG----TVSFHVGTCSSEAQLK 4335
Query: 186 VITRS 190
V ++
Sbjct: 4336 VTAKN 4340
Score = 41.9 bits (94), Expect = 0.002
Identities = 47/187 (25%), Positives = 80/187 (42%), Gaps = 21/187 (11%)
Query: 8 TVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEAS 67
T F C+ T +P + W +R + S + T RL I + D TYTC+
Sbjct: 2932 TAVFTCK-TEHPAATVTWRKGLLELRASGKHQPSQEGLTLRLTISALEKADSDTYTCD-- 2988
Query: 68 NCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVK-GNPSPW 126
+G+A+S A L+V GR++ + V+EG + TF+C + N P
Sbjct: 2989 --IGQAQSRAQLLV--------QGRRVHIIEDLEDVD--VQEGSSATFRCRISPANYEP- 3035
Query: 127 ASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W D + + + + + +L + +++++D G T+ E G ASA L V
Sbjct: 3036 VHWFLDKTPLHANELNEIDAQPGGYHVLTLRQLALKDSG----TIYFEAGDQRASAALRV 3091
Query: 187 ITRSGKF 193
+ F
Sbjct: 3092 TEKPSVF 3098
Score = 40.7 bits (91), Expect = 0.004
Identities = 46/198 (23%), Positives = 78/198 (39%), Gaps = 21/198 (10%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G F+C V+ + D + WF +++ F S + L I + ED G T
Sbjct: 1912 EGGEATFQCVVSPS-DVAVVWFRDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQITV 1970
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
EA A S+A L V L +++ P + VEE +VT + + P
Sbjct: 1971 EAEG----ASSSAALRVREAPVLFK--KKLEP--------QTVEERSSVTLEVELT-RPW 2015
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
P W ++ + + P + + E L + V D G + ++ + A+L
Sbjct: 2016 PELRWTRNATALAPGKNVEI-HAEGARHRLVLHNVGFADRGFFGCETPDD----KTQAKL 2070
Query: 185 EVITRSGKFYGGLRAYSA 202
V R + GL+A A
Sbjct: 2071 TVEMRQVRLVRGLQAVEA 2088
Score = 40.7 bits (91), Expect = 0.004
Identities = 21/57 (36%), Positives = 31/57 (54%), Gaps = 1/57 (1%)
Query: 12 ECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
ECQV+ +RWF ++ ++ +E D +L I V AEDE TYTC+A +
Sbjct: 2310 ECQVS-RASAQVRWFKGSQELQPGPKYELVSDGLYRKLIISDVHAEDEDTYTCDAGD 2365
Score = 37.9 bits (84), Expect = 0.027
Identities = 44/181 (24%), Positives = 74/181 (40%), Gaps = 21/181 (11%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+ VE C+++ P + W + IR ++ + A L I+ + +D G YTCE
Sbjct: 2841 GEDVELRCELSRAGTP-VHWLKDRKAIRKSQKYDVVCEGTMAMLVIRGASLKDAGEYTCE 2899
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
+KS A L V + A F N VEE F C + +P+
Sbjct: 2900 VE----ASKSTASLHV----------EEKANCFTEELTNLQVEEKGTAVFTCKTE-HPAA 2944
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
+W K + S + ++ +R L I + D Y ++G+A++ A+L
Sbjct: 2945 TVTWRKGLLELRASGKHQPSQEGLTLR-LTISALEKADSDTYTC----DIGQAQSRAQLL 2999
Query: 186 V 186
V
Sbjct: 3000 V 3000
Score = 37.9 bits (84), Expect = 0.027
Identities = 44/180 (24%), Positives = 71/180 (39%), Gaps = 21/180 (11%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGT-ARLKIKQVTAEDEGTYT 63
+G T C+++ + W+ E +RD D S DG L+I+ + AED G Y
Sbjct: 3639 EGATAVLRCELSKMAP--VEWWKGHETLRD-GDRHSLRQDGARCELQIRGLVAEDAGEYL 3695
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
C GK +++A L V R M F N+ EG+ T C +
Sbjct: 3696 C----MCGKERTSAMLTV----------RAMPSKFIEGLRNEEATEGDTATLWCEL-SKA 3740
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
+P W K + R ++++ L+I +++ D G Y E A + R
Sbjct: 3741 AP-VEWRKGHETLRDGDRHSLRQDGSRCE-LQIRGLAVVDAGEYSCVCGQERTSATLTVR 3798
Score = 37.5 bits (83), Expect = 0.036
Identities = 50/200 (25%), Positives = 80/200 (40%), Gaps = 25/200 (12%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGT-ARLKIKQVTAEDEGTYT 63
+G T +C++ N + W +E +RD D S DGT L+I+ + D G Y+
Sbjct: 3551 EGATAVLQCEL--NSAAPVEWRKGSETLRD-GDRYSLRQDGTKCELQIRGLAMADTGEYS 3607
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
C G+ +++A L V R + F N+ EG +C +
Sbjct: 3608 C----VCGQERTSAMLTV----------RALPIKFTEGLRNEEATEGATAVLRCEL-SKM 3652
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
+P W K + R ++++ + L+I + ED G Y G+ SA
Sbjct: 3653 AP-VEWWKGHETLRDGDRHSLRQ-DGARCELQIRGLVAEDAGEYLCM----CGKERTSAM 3706
Query: 184 LEVITRSGKFYGGLRAYSAS 203
L V KF GLR A+
Sbjct: 3707 LTVRAMPSKFIEGLRNEEAT 3726
Score = 36.7 bits (81), Expect = 0.063
Identities = 40/163 (24%), Positives = 65/163 (39%), Gaps = 15/163 (9%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTA-RLKIKQVTAEDEGTYTC 64
G +FEC+ T + W+ + + D GT RL VT +DEGTY+C
Sbjct: 812 GGPAQFECE-TSEAHVHVHWYKDGMELGHSGERFLQEDVGTRHRLVAATVTRQDEGTYSC 870
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
+G+ + L V + + + Q+A E G + T C V
Sbjct: 871 R----VGEDSVDFRLRVSEPKVVFAK-EQLARR------KLQAEAGASATLSCEV-AQAQ 918
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIY 167
+W KDG ++ S+++ + E R L + + D G Y
Sbjct: 919 TEVTWYKDGKKLSSSSKVCM-EATGCTRRLVVQQAGQADAGEY 960
Score = 36.7 bits (81), Expect = 0.063
Identities = 25/82 (30%), Positives = 37/82 (45%), Gaps = 6/82 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWF-HYAE-----VIRDCADFESSYDDGTARLKIKQVTAEDE 59
G ++ F +V G P P + W AE + D + + L + V + +
Sbjct: 5385 GSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLDVGRQHQ 5444
Query: 60 GTYTCEASNCLGKAKSNACLVV 81
GTYTC ASN G+A +A L V
Sbjct: 5445 GTYTCIASNAAGQALCSASLHV 5466
Score = 36.7 bits (81), Expect = 0.063
Identities = 22/79 (27%), Positives = 31/79 (39%)
Query: 108 EEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIY 167
E GE V C V G P P SW KDG + + E + L +D ++ D G Y
Sbjct: 6026 ELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQY 6085
Query: 168 RITVENELGRAEASARLEV 186
+ G ++ V
Sbjct: 6086 MCFAASAAGNCSTLGKILV 6104
Score = 35.5 bits (78), Expect = 0.15
Identities = 41/178 (23%), Positives = 72/178 (40%), Gaps = 19/178 (10%)
Query: 8 TVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEAS 67
T+ +C+V+ +P+ + W + ++ + GT L + V+ ED G YTC
Sbjct: 2663 TLALQCEVS-DPEAHVVWRKDGVQLGPSDKYDFLHTAGTRGLVVHDVSPEDAGLYTCHVG 2721
Query: 68 NCLGKAKSNA-CLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVK-GNPSP 125
+ +A+ L V T+RL + V EGE+ +F+C + + S
Sbjct: 2722 SEETRARVRVHDLHVGITKRLKT---------------MEVLEGESCSFECVLSHESASD 2766
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
A W G + S+R ++ IL + E + D G +V +A R
Sbjct: 2767 PAMWTVGGKTVGSSSRFQA-TRQGRKYILVVREAAPSDAGEVVFSVRGLTSKASLIVR 2823
Score = 35.5 bits (78), Expect = 0.15
Identities = 46/190 (24%), Positives = 73/190 (38%), Gaps = 24/190 (12%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGT-ARLKIKQVTAEDEGTYT 63
+G T +C+++ + W +E +R D S DGT L+I ++ D G Y+
Sbjct: 3815 EGATAVLQCELS--KAAPVEWRKGSETLRG-GDRYSLRQDGTRCELQIHGLSVADTGEYS 3871
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
C G+ +++A L V R P F + EEG T +C + P
Sbjct: 3872 C----VCGQERTSATLTV----------RAPQPVFREPLQSLQAEEGSTATLQCEL-SEP 3916
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
+ W K G + + R + L + ++ ED G Y T G SA
Sbjct: 3917 TATVVWSKGGLQLQANGR-REPRLQGCTAELVLQDLQREDTGEYTCT----CGSQATSAT 3971
Query: 184 LEVITRSGKF 193
L V +F
Sbjct: 3972 LTVTAAPVRF 3981
Score = 34.7 bits (76), Expect = 0.26
Identities = 16/64 (25%), Positives = 29/64 (45%), Gaps = 1/64 (1%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G T C+++ + W + + CA ++ D A L ++ V ED G YTC
Sbjct: 3992 EGGTAHLCCELS-RAGASVEWRKGSLQLFPCAKYQMVQDGAAAELLVRGVEQEDAGDYTC 4050
Query: 65 EASN 68
+ +
Sbjct: 4051 DTGH 4054
Score = 32.7 bits (71), Expect = 1.0
Identities = 42/194 (21%), Positives = 74/194 (38%), Gaps = 23/194 (11%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G T C+++ + W +E +RD + D L+I+ + D Y+C
Sbjct: 3287 EGATATLRCELS--KAAPVEWRKGSETLRDGDRYCLRQDGAMCELQIRGLAMVDAAEYSC 3344
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
G+ +++A L + R M F ++ EG T +C + +
Sbjct: 3345 ----VCGEERTSASLTI----------RPMPAHFIGRLRHQESIEGATATLRCEL-SKAA 3389
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
P W K + R ++++ + L+I +++ D G Y G SA L
Sbjct: 3390 P-VEWRKGRESLRDGDRHSLRQDGAVCE-LQICGLAVADAGEYSCV----CGEERTSATL 3443
Query: 185 EVITRSGKFYGGLR 198
V KF GLR
Sbjct: 3444 TVKALPAKFTEGLR 3457
Score = 31.9 bits (69), Expect = 1.8
Identities = 23/71 (32%), Positives = 32/71 (45%), Gaps = 2/71 (2%)
Query: 108 EEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIY 167
EE + +C V +P W KDG + PS + R L + +VS ED G+Y
Sbjct: 2659 EERGTLALQCEVS-DPEAHVVWRKDGVQLGPSDKYDFLHTAGT-RGLVVHDVSPEDAGLY 2716
Query: 168 RITVENELGRA 178
V +E RA
Sbjct: 2717 TCHVGSEETRA 2727
Score = 31.5 bits (68), Expect = 2.4
Identities = 15/59 (25%), Positives = 27/59 (45%), Gaps = 1/59 (1%)
Query: 7 DTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
++ F C+V P + WF + A + + RL ++ V+A+D+ Y CE
Sbjct: 348 ESATFLCEVP-QPSTEAAWFKEETRLWASAKYGIEEEGTERRLTVRNVSADDDAVYICE 405
Score = 30.7 bits (66), Expect = 4.2
Identities = 21/92 (22%), Positives = 36/92 (39%), Gaps = 1/92 (1%)
Query: 92 RQMAPTFYTYPFNKV-VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEI 150
+Q +++ F + G+ + +C V A W KDG +T + + +
Sbjct: 4893 KQQEGPMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLGDG 4952
Query: 151 MRILEIDEVSIEDVGIYRITVENELGRAEASA 182
L I + D G Y V N+ G+ SA
Sbjct: 4953 TCSLLITGLDRADAGCYTCQVSNKFGQVTHSA 4984
Score = 30.3 bits (65), Expect = 5.5
Identities = 40/180 (22%), Positives = 66/180 (36%), Gaps = 17/180 (9%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G T +C+++ P + W ++ E TA L ++ + ED G YTC
Sbjct: 3903 EGSTATLQCELS-EPTATVVWSKGGLQLQANGRREPRLQGCTAELVLQDLQREDTGEYTC 3961
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
C G ++A L V ++P R F ++ V+EG C
Sbjct: 3962 ---TC-GSQATSATLTV-----TAAPVR-----FLRELQHQEVDEG-GTAHLCCELSRAG 4006
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
W K + P A+ + + +L + V ED G Y + A S R+
Sbjct: 4007 ASVEWRKGSLQLFPCAKYQMVQDGAAAELL-VRGVEQEDAGDYTCDTGHTQSMASLSVRV 4065
Score = 29.9 bits (64), Expect = 7.3
Identities = 44/195 (22%), Positives = 73/195 (37%), Gaps = 20/195 (10%)
Query: 23 IRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLGKAKSNACLVVY 82
++W+ + F+ S + A L+I ++ D G Y C+A G A S+ + V
Sbjct: 2499 VQWYKDDTPLSPSEKFKMSLEGQMAELRILRLMPADAGVYRCQA----GSAHSSTEVTV- 2553
Query: 83 HTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARI 142
R ++ G + EEG +F C + + W +G + +
Sbjct: 2554 EAREVTVTGPLQDA--------EATEEGW-ASFSCEL-SHEDEEVEWSLNGMPLYNDSFH 2603
Query: 143 TVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVITRSGKFYGGLRAYSA 202
+ K L + + D GI R + + SARLEV + F L SA
Sbjct: 2604 EISHKGR-RHTLVLKSIQRADAGIVRASSL----KVSTSARLEVRVKPVVFLKALDDLSA 2658
Query: 203 SPRKCLSYRRRPSTP 217
R L+ + S P
Sbjct: 2659 EERGTLALQCEVSDP 2673
Score = 29.9 bits (64), Expect = 7.3
Identities = 19/59 (32%), Positives = 25/59 (42%), Gaps = 1/59 (1%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
G+ V E +V ++ W E I+ FE L IK TAED+G Y C
Sbjct: 4638 GEDVSLELEVVAEAG-EVIWHKGMERIQPGGRFEVVSQGRQQMLVIKGFTAEDQGEYHC 4695
>AL359510-13|CAI15072.1| 6620|Homo sapiens obscurin, cytoskeletal
calmodulin and titin-interacting RhoGEF protein.
Length = 6620
Score = 96.3 bits (229), Expect = 7e-20
Identities = 67/221 (30%), Positives = 93/221 (42%), Gaps = 14/221 (6%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G CQ+ GNP P + W + + A F + D RL I + D G Y C
Sbjct: 24 GKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTILDLALGDSGQYVCR 83
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A N +G+A + L V + + AP F P + V EG TF+C V G+P P
Sbjct: 84 ARNAIGEAFAAVGLQV----DAEAACAEQAPHFLLRPTSIRVREGSEATFRCRVGGSPRP 139
Query: 126 WASWDKDGSII--TPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
SW KDG + R+ V+E E L I D G Y + EN LG A A+A
Sbjct: 140 AVSWSKDGRRLGEPDGPRVRVEELGE-ASALRIRAARPRDGGTYEVRAENPLGAASAAAA 198
Query: 184 L-------EVITRSGKFYGGLRAYSASPRKCLSYRRRPSTP 217
L + +R G L A+ R+ + P++P
Sbjct: 199 LVVDSDAADTASRPGTSTAALLAHLQRRREAMRAEGAPASP 239
Score = 92.3 bits (219), Expect = 1e-18
Identities = 56/183 (30%), Positives = 86/183 (46%), Gaps = 13/183 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIR-DCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
G+TV+ C+VTG P P I W+ + ++ D DG+ L + +T D G Y C
Sbjct: 6028 GETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQYMC 6087
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
A++ G + ++V Q+ P F EGE+ F C ++G P
Sbjct: 6088 FAASAAGNCSTLGKILV-----------QVPPRFVNKVRASPFVEGEDAQFTCTIEGAPY 6136
Query: 125 PWASWDKDGSIITPSARI-TVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
P W KDG+++T + T+ E + +L I S ED+G+Y + N LG A ASA
Sbjct: 6137 PQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAE 6196
Query: 184 LEV 186
L +
Sbjct: 6197 LRI 6199
Score = 62.5 bits (145), Expect = 1e-09
Identities = 32/92 (34%), Positives = 45/92 (48%)
Query: 95 APTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRIL 154
AP F T N+ V++G V+F C V G P P W KDG ++ + E ++ L
Sbjct: 5125 APVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQL 5184
Query: 155 EIDEVSIEDVGIYRITVENELGRAEASARLEV 186
I V D+G+YR EN +G + A L V
Sbjct: 5185 IITAVVPADMGVYRCLAENSMGVSSTKAELRV 5216
Score = 62.1 bits (144), Expect = 1e-09
Identities = 32/100 (32%), Positives = 51/100 (51%), Gaps = 1/100 (1%)
Query: 87 LSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKE 146
+ P AP F T P VV G++ T C + GNP+P SW+KD + AR + +
Sbjct: 1 MDQPQFSGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQ 60
Query: 147 KEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
++ R+ +D +++ D G Y N +G A A+ L+V
Sbjct: 61 DGDLYRLTILD-LALGDSGQYVCRARNAIGEAFAAVGLQV 99
Score = 62.1 bits (144), Expect = 1e-09
Identities = 50/165 (30%), Positives = 74/165 (44%), Gaps = 15/165 (9%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTAR--LKIKQVTAEDEGTY 62
+G C VTG P P+ W +++ + Y+D LKI D G Y
Sbjct: 251 EGKHARLSCYVTGEPKPETVWKKDGQLVTE-GRRHVVYEDAQENFVLKILFCKQSDRGLY 309
Query: 63 TCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGN 122
TC ASN +G+ S+ +VV R+ A F + V E E+ TF C V
Sbjct: 310 TCTASNLVGQTYSSVLVVV----------REPAVPFKKRLQDLEVREKESATFLCEVP-Q 358
Query: 123 PSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIY 167
PS A+W K+ + + SA+ + E+E R L + VS +D +Y
Sbjct: 359 PSTEAAWFKEETRLWASAKYGI-EEEGTERRLTVRNVSADDDAVY 402
Score = 60.9 bits (141), Expect = 3e-09
Identities = 56/206 (27%), Positives = 82/206 (39%), Gaps = 24/206 (11%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDD-GTAR-LKIKQVTAEDEGTY 62
+G F C+V G+P P + W + + ++ G A L+I+ D GTY
Sbjct: 123 EGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGTY 182
Query: 63 TCEASNCLGKAKSNACLVV--------------------YHTRRLSSPGRQMAPTF--YT 100
A N LG A + A LVV + RR + + AP T
Sbjct: 183 EVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQRRREAMRAEGAPASPPST 242
Query: 101 YPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVS 160
V EG++ C V G P P W KDG ++T R V E + +L+I
Sbjct: 243 GTRTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCK 302
Query: 161 IEDVGIYRITVENELGRAEASARLEV 186
D G+Y T N +G+ +S + V
Sbjct: 303 QSDRGLYTCTASNLVGQTYSSVLVVV 328
Score = 60.9 bits (141), Expect = 3e-09
Identities = 50/191 (26%), Positives = 81/191 (42%), Gaps = 17/191 (8%)
Query: 10 EFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNC 69
+F+ +V G P P + WF + + A + L+I VT ED G Y SN
Sbjct: 5279 KFQLKVKGYPAPRLYWFKDGQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNA 5338
Query: 70 LGKAKSNACLVVY-----HTRRLSSPGRQMAPTFYTYPFN-KVVEEGENVTFKCAVKGNP 123
+G A S+A L+V + S Q+ P F K V++G ++TF V+G P
Sbjct: 5339 MGAAYSSARLLVRGPDEPEEKPASDVHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGRP 5398
Query: 124 SPWASW---DKDGSII-----TPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENEL 175
P W + + ++ TP + ++ + +L++ + G Y N
Sbjct: 5399 VPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLDVGR---QHQGTYTCIASNAA 5455
Query: 176 GRAEASARLEV 186
G+A SA L V
Sbjct: 5456 GQALCSASLHV 5466
Score = 52.0 bits (119), Expect = 2e-06
Identities = 28/78 (35%), Positives = 40/78 (51%), Gaps = 1/78 (1%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYD-DGTARLKIKQVTAEDEGTYT 63
DG V F+C VTG P P +RWF +++ + + + D G +L I V D G Y
Sbjct: 5139 DGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQLIITAVVPADMGVYR 5198
Query: 64 CEASNCLGKAKSNACLVV 81
C A N +G + + A L V
Sbjct: 5199 CLAENSMGVSSTKAELRV 5216
Score = 48.8 bits (111), Expect = 1e-05
Identities = 25/75 (33%), Positives = 38/75 (50%), Gaps = 2/75 (2%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFE--SSYDDGTARLKIKQVTAEDEGTY 62
+G+ +F C + G P P IRW+ ++ F+ S G L I+ + ED G Y
Sbjct: 6121 EGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLY 6180
Query: 63 TCEASNCLGKAKSNA 77
CE N LG A+++A
Sbjct: 6181 ECELVNRLGSARASA 6195
Score = 48.4 bits (110), Expect = 2e-05
Identities = 26/77 (33%), Positives = 33/77 (42%), Gaps = 1/77 (1%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFE-SSYDDGTARLKIKQVTAEDEGTYTC 64
GD + EC V D RW + D DGT L I + D G YTC
Sbjct: 4912 GDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLGDGTCSLLITGLDRADAGCYTC 4971
Query: 65 EASNCLGKAKSNACLVV 81
+ SN G+ +AC+VV
Sbjct: 4972 QVSNKFGQVTHSACVVV 4988
Score = 44.8 bits (101), Expect = 2e-04
Identities = 48/180 (26%), Positives = 80/180 (44%), Gaps = 20/180 (11%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G TV C+++ ++ W +R F+ + L + + AED G Y CE
Sbjct: 1823 GGTVTLACELSP-ACAEVVWRCGNTQLRVGKRFQMVAEGPVRSLTVLGLRAEDAGEYVCE 1881
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
+ + ++A L V R + F + V EEG TF+C V +PS
Sbjct: 1882 SRD----DHTSAQLTVSVPRVVK---------FMSGLSTVVAEEGGEATFQCVV--SPSD 1926
Query: 126 WA-SWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
A W +DG+++ PS + + + L I ++ +ED G +ITVE E + A+ R+
Sbjct: 1927 VAVVWFRDGALLQPSEKFAISQ-SGASHSLTISDLVLEDAG--QITVEAEGASSSAALRV 1983
Score = 44.4 bits (100), Expect = 3e-04
Identities = 40/163 (24%), Positives = 65/163 (39%), Gaps = 16/163 (9%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G T C+V P ++ W+ + + + T RL ++QV D G Y+CE
Sbjct: 1181 GTTAMLSCEVA-QPQTEVTWYKDGKKLSSSSKVRMEVKGCTRRLVVQQVGKADAGEYSCE 1239
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKV-VEEGENVTFKCAVKGNPS 124
A G+ V ++ P A + N+V E G + T C V
Sbjct: 1240 AG---GQR-------VSFQLHITEPKAVFAKEQLVH--NEVRTEAGASATLSCEV-AQAQ 1286
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIY 167
+W KDG ++ S+++ + E MR L + + D G Y
Sbjct: 1287 TEVTWYKDGKKLSSSSKVRI-EAAGCMRQLVVQQAGQADAGEY 1328
Score = 44.4 bits (100), Expect = 3e-04
Identities = 51/199 (25%), Positives = 84/199 (42%), Gaps = 21/199 (10%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G+ + C+ T D + W + +R A + S++ A+L I T +D G Y C
Sbjct: 3109 EGEDLTLVCE-TSTCDIPVCWTKDGKTLRGSARCQLSHEGHRAQLLITGATLQDSGRYKC 3167
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
EA G A S++ +V H R P R F + V EG T +C + +
Sbjct: 3168 EA----GGACSSS-IVRVHAR----PVR-----FQEALKDLEVLEGGAATLRCVLSSVAA 3213
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
P W +++ P + ++++ E M L + + +D G Y + G SA L
Sbjct: 3214 P-VKWCYGNNVLRPGDKYSLRQ-EGAMLELVVRNLRPQDSGRYSCS----FGDQTTSATL 3267
Query: 185 EVITRSGKFYGGLRAYSAS 203
V +F G LR A+
Sbjct: 3268 TVTALPAQFIGKLRNKEAT 3286
Score = 42.7 bits (96), Expect = 0.001
Identities = 43/185 (23%), Positives = 79/185 (42%), Gaps = 19/185 (10%)
Query: 7 DTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTAR-LKIKQVTAEDEGTYTCE 65
+ VEF C+V+ ++W ++ E + DG L++K VT ED GT +
Sbjct: 4174 EDVEFSCEVSRAGATGVQWCLQGLPLQSNEVTEVAVRDGRIHTLRLKGVTPEDAGTVSFH 4233
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
LG S+A L V R T + + EG++ +F+C +
Sbjct: 4234 ----LGNHASSAQLTV----------RAPEVTILEPLQDVQLSEGQDASFQCRLSRASGQ 4279
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
A W G + + + ++ + +L + +V++ED G TV +G + A+L+
Sbjct: 4280 EARWALGGVPLQANEMNDITVEQGTLHLLTLHKVTLEDAG----TVSFHVGTCSSEAQLK 4335
Query: 186 VITRS 190
V ++
Sbjct: 4336 VTAKN 4340
Score = 41.9 bits (94), Expect = 0.002
Identities = 47/187 (25%), Positives = 80/187 (42%), Gaps = 21/187 (11%)
Query: 8 TVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEAS 67
T F C+ T +P + W +R + S + T RL I + D TYTC+
Sbjct: 2932 TAVFTCK-TEHPAATVTWRKGLLELRASGKHQPSQEGLTLRLTISALEKADSDTYTCD-- 2988
Query: 68 NCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVK-GNPSPW 126
+G+A+S A L+V GR++ + V+EG + TF+C + N P
Sbjct: 2989 --IGQAQSRAQLLV--------QGRRVHIIEDLEDVD--VQEGSSATFRCRISPANYEP- 3035
Query: 127 ASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W D + + + + + +L + +++++D G T+ E G ASA L V
Sbjct: 3036 VHWFLDKTPLHANELNEIDAQPGGYHVLTLRQLALKDSG----TIYFEAGDQRASAALRV 3091
Query: 187 ITRSGKF 193
+ F
Sbjct: 3092 TEKPSVF 3098
Score = 40.7 bits (91), Expect = 0.004
Identities = 46/198 (23%), Positives = 78/198 (39%), Gaps = 21/198 (10%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G F+C V+ + D + WF +++ F S + L I + ED G T
Sbjct: 1912 EGGEATFQCVVSPS-DVAVVWFRDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQITV 1970
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
EA A S+A L V L +++ P + VEE +VT + + P
Sbjct: 1971 EAEG----ASSSAALRVREAPVLFK--KKLEP--------QTVEERSSVTLEVELT-RPW 2015
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
P W ++ + + P + + E L + V D G + ++ + A+L
Sbjct: 2016 PELRWTRNATALAPGKNVEI-HAEGARHRLVLHNVGFADRGFFGCETPDD----KTQAKL 2070
Query: 185 EVITRSGKFYGGLRAYSA 202
V R + GL+A A
Sbjct: 2071 TVEMRQVRLVRGLQAVEA 2088
Score = 40.7 bits (91), Expect = 0.004
Identities = 21/57 (36%), Positives = 31/57 (54%), Gaps = 1/57 (1%)
Query: 12 ECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
ECQV+ +RWF ++ ++ +E D +L I V AEDE TYTC+A +
Sbjct: 2310 ECQVS-RASAQVRWFKGSQELQPGPKYELVSDGLYRKLIISDVHAEDEDTYTCDAGD 2365
Score = 37.9 bits (84), Expect = 0.027
Identities = 44/181 (24%), Positives = 74/181 (40%), Gaps = 21/181 (11%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+ VE C+++ P + W + IR ++ + A L I+ + +D G YTCE
Sbjct: 2841 GEDVELRCELSRAGTP-VHWLKDRKAIRKSQKYDVVCEGTMAMLVIRGASLKDAGEYTCE 2899
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
+KS A L V + A F N VEE F C + +P+
Sbjct: 2900 VE----ASKSTASLHV----------EEKANCFTEELTNLQVEEKGTAVFTCKTE-HPAA 2944
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
+W K + S + ++ +R L I + D Y ++G+A++ A+L
Sbjct: 2945 TVTWRKGLLELRASGKHQPSQEGLTLR-LTISALEKADSDTYTC----DIGQAQSRAQLL 2999
Query: 186 V 186
V
Sbjct: 3000 V 3000
Score = 37.9 bits (84), Expect = 0.027
Identities = 44/180 (24%), Positives = 71/180 (39%), Gaps = 21/180 (11%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGT-ARLKIKQVTAEDEGTYT 63
+G T C+++ + W+ E +RD D S DG L+I+ + AED G Y
Sbjct: 3639 EGATAVLRCELSKMAP--VEWWKGHETLRD-GDRHSLRQDGARCELQIRGLVAEDAGEYL 3695
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
C GK +++A L V R M F N+ EG+ T C +
Sbjct: 3696 C----MCGKERTSAMLTV----------RAMPSKFIEGLRNEEATEGDTATLWCEL-SKA 3740
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
+P W K + R ++++ L+I +++ D G Y E A + R
Sbjct: 3741 AP-VEWRKGHETLRDGDRHSLRQDGSRCE-LQIRGLAVVDAGEYSCVCGQERTSATLTVR 3798
Score = 37.5 bits (83), Expect = 0.036
Identities = 50/200 (25%), Positives = 80/200 (40%), Gaps = 25/200 (12%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGT-ARLKIKQVTAEDEGTYT 63
+G T +C++ N + W +E +RD D S DGT L+I+ + D G Y+
Sbjct: 3551 EGATAVLQCEL--NSAAPVEWRKGSETLRD-GDRYSLRQDGTKCELQIRGLAMADTGEYS 3607
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
C G+ +++A L V R + F N+ EG +C +
Sbjct: 3608 C----VCGQERTSAMLTV----------RALPIKFTEGLRNEEATEGATAVLRCEL-SKM 3652
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
+P W K + R ++++ + L+I + ED G Y G+ SA
Sbjct: 3653 AP-VEWWKGHETLRDGDRHSLRQ-DGARCELQIRGLVAEDAGEYLCM----CGKERTSAM 3706
Query: 184 LEVITRSGKFYGGLRAYSAS 203
L V KF GLR A+
Sbjct: 3707 LTVRAMPSKFIEGLRNEEAT 3726
Score = 36.7 bits (81), Expect = 0.063
Identities = 40/163 (24%), Positives = 65/163 (39%), Gaps = 15/163 (9%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTA-RLKIKQVTAEDEGTYTC 64
G +FEC+ T + W+ + + D GT RL VT +DEGTY+C
Sbjct: 812 GGPAQFECE-TSEAHVHVHWYKDGMELGHSGERFLQEDVGTRHRLVAATVTRQDEGTYSC 870
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
+G+ + L V + + + Q+A E G + T C V
Sbjct: 871 R----VGEDSVDFRLRVSEPKVVFAK-EQLARR------KLQAEAGASATLSCEV-AQAQ 918
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIY 167
+W KDG ++ S+++ + E R L + + D G Y
Sbjct: 919 TEVTWYKDGKKLSSSSKVCM-EATGCTRRLVVQQAGQADAGEY 960
Score = 36.7 bits (81), Expect = 0.063
Identities = 25/82 (30%), Positives = 37/82 (45%), Gaps = 6/82 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWF-HYAE-----VIRDCADFESSYDDGTARLKIKQVTAEDE 59
G ++ F +V G P P + W AE + D + + L + V + +
Sbjct: 5385 GSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLDVGRQHQ 5444
Query: 60 GTYTCEASNCLGKAKSNACLVV 81
GTYTC ASN G+A +A L V
Sbjct: 5445 GTYTCIASNAAGQALCSASLHV 5466
Score = 36.7 bits (81), Expect = 0.063
Identities = 22/79 (27%), Positives = 31/79 (39%)
Query: 108 EEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIY 167
E GE V C V G P P SW KDG + + E + L +D ++ D G Y
Sbjct: 6026 ELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQY 6085
Query: 168 RITVENELGRAEASARLEV 186
+ G ++ V
Sbjct: 6086 MCFAASAAGNCSTLGKILV 6104
Score = 35.5 bits (78), Expect = 0.15
Identities = 41/178 (23%), Positives = 72/178 (40%), Gaps = 19/178 (10%)
Query: 8 TVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEAS 67
T+ +C+V+ +P+ + W + ++ + GT L + V+ ED G YTC
Sbjct: 2663 TLALQCEVS-DPEAHVVWRKDGVQLGPSDKYDFLHTAGTRGLVVHDVSPEDAGLYTCHVG 2721
Query: 68 NCLGKAKSNA-CLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVK-GNPSP 125
+ +A+ L V T+RL + V EGE+ +F+C + + S
Sbjct: 2722 SEETRARVRVHDLHVGITKRLKT---------------MEVLEGESCSFECVLSHESASD 2766
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
A W G + S+R ++ IL + E + D G +V +A R
Sbjct: 2767 PAMWTVGGKTVGSSSRFQA-TRQGRKYILVVREAAPSDAGEVVFSVRGLTSKASLIVR 2823
Score = 35.5 bits (78), Expect = 0.15
Identities = 46/190 (24%), Positives = 73/190 (38%), Gaps = 24/190 (12%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGT-ARLKIKQVTAEDEGTYT 63
+G T +C+++ + W +E +R D S DGT L+I ++ D G Y+
Sbjct: 3815 EGATAVLQCELS--KAAPVEWRKGSETLRG-GDRYSLRQDGTRCELQIHGLSVADTGEYS 3871
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
C G+ +++A L V R P F + EEG T +C + P
Sbjct: 3872 C----VCGQERTSATLTV----------RAPQPVFREPLQSLQAEEGSTATLQCEL-SEP 3916
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
+ W K G + + R + L + ++ ED G Y T G SA
Sbjct: 3917 TATVVWSKGGLQLQANGR-REPRLQGCTAELVLQDLQREDTGEYTCT----CGSQATSAT 3971
Query: 184 LEVITRSGKF 193
L V +F
Sbjct: 3972 LTVTAAPVRF 3981
Score = 34.7 bits (76), Expect = 0.26
Identities = 16/64 (25%), Positives = 29/64 (45%), Gaps = 1/64 (1%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G T C+++ + W + + CA ++ D A L ++ V ED G YTC
Sbjct: 3992 EGGTAHLCCELS-RAGASVEWRKGSLQLFPCAKYQMVQDGAAAELLVRGVEQEDAGDYTC 4050
Query: 65 EASN 68
+ +
Sbjct: 4051 DTGH 4054
Score = 32.7 bits (71), Expect = 1.0
Identities = 42/194 (21%), Positives = 74/194 (38%), Gaps = 23/194 (11%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G T C+++ + W +E +RD + D L+I+ + D Y+C
Sbjct: 3287 EGATATLRCELS--KAAPVEWRKGSETLRDGDRYCLRQDGAMCELQIRGLAMVDAAEYSC 3344
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
G+ +++A L + R M F ++ EG T +C + +
Sbjct: 3345 ----VCGEERTSASLTI----------RPMPAHFIGRLRHQESIEGATATLRCEL-SKAA 3389
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
P W K + R ++++ + L+I +++ D G Y G SA L
Sbjct: 3390 P-VEWRKGRESLRDGDRHSLRQDGAVCE-LQICGLAVADAGEYSCV----CGEERTSATL 3443
Query: 185 EVITRSGKFYGGLR 198
V KF GLR
Sbjct: 3444 TVKALPAKFTEGLR 3457
Score = 31.9 bits (69), Expect = 1.8
Identities = 23/71 (32%), Positives = 32/71 (45%), Gaps = 2/71 (2%)
Query: 108 EEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIY 167
EE + +C V +P W KDG + PS + R L + +VS ED G+Y
Sbjct: 2659 EERGTLALQCEVS-DPEAHVVWRKDGVQLGPSDKYDFLHTAGT-RGLVVHDVSPEDAGLY 2716
Query: 168 RITVENELGRA 178
V +E RA
Sbjct: 2717 TCHVGSEETRA 2727
Score = 31.5 bits (68), Expect = 2.4
Identities = 15/59 (25%), Positives = 27/59 (45%), Gaps = 1/59 (1%)
Query: 7 DTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
++ F C+V P + WF + A + + RL ++ V+A+D+ Y CE
Sbjct: 348 ESATFLCEVP-QPSTEAAWFKEETRLWASAKYGIEEEGTERRLTVRNVSADDDAVYICE 405
Score = 30.7 bits (66), Expect = 4.2
Identities = 21/92 (22%), Positives = 36/92 (39%), Gaps = 1/92 (1%)
Query: 92 RQMAPTFYTYPFNKV-VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEI 150
+Q +++ F + G+ + +C V A W KDG +T + + +
Sbjct: 4893 KQQEGPMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLGDG 4952
Query: 151 MRILEIDEVSIEDVGIYRITVENELGRAEASA 182
L I + D G Y V N+ G+ SA
Sbjct: 4953 TCSLLITGLDRADAGCYTCQVSNKFGQVTHSA 4984
Score = 30.3 bits (65), Expect = 5.5
Identities = 40/180 (22%), Positives = 66/180 (36%), Gaps = 17/180 (9%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G T +C+++ P + W ++ E TA L ++ + ED G YTC
Sbjct: 3903 EGSTATLQCELS-EPTATVVWSKGGLQLQANGRREPRLQGCTAELVLQDLQREDTGEYTC 3961
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
C G ++A L V ++P R F ++ V+EG C
Sbjct: 3962 ---TC-GSQATSATLTV-----TAAPVR-----FLRELQHQEVDEG-GTAHLCCELSRAG 4006
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
W K + P A+ + + +L + V ED G Y + A S R+
Sbjct: 4007 ASVEWRKGSLQLFPCAKYQMVQDGAAAELL-VRGVEQEDAGDYTCDTGHTQSMASLSVRV 4065
Score = 29.9 bits (64), Expect = 7.3
Identities = 44/195 (22%), Positives = 73/195 (37%), Gaps = 20/195 (10%)
Query: 23 IRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLGKAKSNACLVVY 82
++W+ + F+ S + A L+I ++ D G Y C+A G A S+ + V
Sbjct: 2499 VQWYKDDTPLSPSEKFKMSLEGQMAELRILRLMPADAGVYRCQA----GSAHSSTEVTV- 2553
Query: 83 HTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARI 142
R ++ G + EEG +F C + + W +G + +
Sbjct: 2554 EAREVTVTGPLQDA--------EATEEGW-ASFSCEL-SHEDEEVEWSLNGMPLYNDSFH 2603
Query: 143 TVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVITRSGKFYGGLRAYSA 202
+ K L + + D GI R + + SARLEV + F L SA
Sbjct: 2604 EISHKGR-RHTLVLKSIQRADAGIVRASSL----KVSTSARLEVRVKPVVFLKALDDLSA 2658
Query: 203 SPRKCLSYRRRPSTP 217
R L+ + S P
Sbjct: 2659 EERGTLALQCEVSDP 2673
Score = 29.9 bits (64), Expect = 7.3
Identities = 19/59 (32%), Positives = 25/59 (42%), Gaps = 1/59 (1%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
G+ V E +V ++ W E I+ FE L IK TAED+G Y C
Sbjct: 4638 GEDVSLELEVVAEAG-EVIWHKGMERIQPGGRFEVVSQGRQQMLVIKGFTAEDQGEYHC 4695
>AL353593-3|CAI19285.1| 6620|Homo sapiens obscurin, cytoskeletal
calmodulin and titin-interacting RhoGEF protein.
Length = 6620
Score = 96.3 bits (229), Expect = 7e-20
Identities = 67/221 (30%), Positives = 93/221 (42%), Gaps = 14/221 (6%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G CQ+ GNP P + W + + A F + D RL I + D G Y C
Sbjct: 24 GKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTILDLALGDSGQYVCR 83
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A N +G+A + L V + + AP F P + V EG TF+C V G+P P
Sbjct: 84 ARNAIGEAFAAVGLQV----DAEAACAEQAPHFLLRPTSIRVREGSEATFRCRVGGSPRP 139
Query: 126 WASWDKDGSII--TPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
SW KDG + R+ V+E E L I D G Y + EN LG A A+A
Sbjct: 140 AVSWSKDGRRLGEPDGPRVRVEELGE-ASALRIRAARPRDGGTYEVRAENPLGAASAAAA 198
Query: 184 L-------EVITRSGKFYGGLRAYSASPRKCLSYRRRPSTP 217
L + +R G L A+ R+ + P++P
Sbjct: 199 LVVDSDAADTASRPGTSTAALLAHLQRRREAMRAEGAPASP 239
Score = 92.3 bits (219), Expect = 1e-18
Identities = 56/183 (30%), Positives = 86/183 (46%), Gaps = 13/183 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIR-DCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
G+TV+ C+VTG P P I W+ + ++ D DG+ L + +T D G Y C
Sbjct: 6028 GETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQYMC 6087
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
A++ G + ++V Q+ P F EGE+ F C ++G P
Sbjct: 6088 FAASAAGNCSTLGKILV-----------QVPPRFVNKVRASPFVEGEDAQFTCTIEGAPY 6136
Query: 125 PWASWDKDGSIITPSARI-TVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
P W KDG+++T + T+ E + +L I S ED+G+Y + N LG A ASA
Sbjct: 6137 PQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAE 6196
Query: 184 LEV 186
L +
Sbjct: 6197 LRI 6199
Score = 62.5 bits (145), Expect = 1e-09
Identities = 32/92 (34%), Positives = 45/92 (48%)
Query: 95 APTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRIL 154
AP F T N+ V++G V+F C V G P P W KDG ++ + E ++ L
Sbjct: 5125 APVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQL 5184
Query: 155 EIDEVSIEDVGIYRITVENELGRAEASARLEV 186
I V D+G+YR EN +G + A L V
Sbjct: 5185 IITAVVPADMGVYRCLAENSMGVSSTKAELRV 5216
Score = 62.1 bits (144), Expect = 1e-09
Identities = 32/100 (32%), Positives = 51/100 (51%), Gaps = 1/100 (1%)
Query: 87 LSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKE 146
+ P AP F T P VV G++ T C + GNP+P SW+KD + AR + +
Sbjct: 1 MDQPQFSGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQ 60
Query: 147 KEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
++ R+ +D +++ D G Y N +G A A+ L+V
Sbjct: 61 DGDLYRLTILD-LALGDSGQYVCRARNAIGEAFAAVGLQV 99
Score = 62.1 bits (144), Expect = 1e-09
Identities = 50/165 (30%), Positives = 74/165 (44%), Gaps = 15/165 (9%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTAR--LKIKQVTAEDEGTY 62
+G C VTG P P+ W +++ + Y+D LKI D G Y
Sbjct: 251 EGKHARLSCYVTGEPKPETVWKKDGQLVTE-GRRHVVYEDAQENFVLKILFCKQSDRGLY 309
Query: 63 TCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGN 122
TC ASN +G+ S+ +VV R+ A F + V E E+ TF C V
Sbjct: 310 TCTASNLVGQTYSSVLVVV----------REPAVPFKKRLQDLEVREKESATFLCEVP-Q 358
Query: 123 PSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIY 167
PS A+W K+ + + SA+ + E+E R L + VS +D +Y
Sbjct: 359 PSTEAAWFKEETRLWASAKYGI-EEEGTERRLTVRNVSADDDAVY 402
Score = 60.9 bits (141), Expect = 3e-09
Identities = 56/206 (27%), Positives = 82/206 (39%), Gaps = 24/206 (11%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDD-GTAR-LKIKQVTAEDEGTY 62
+G F C+V G+P P + W + + ++ G A L+I+ D GTY
Sbjct: 123 EGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGTY 182
Query: 63 TCEASNCLGKAKSNACLVV--------------------YHTRRLSSPGRQMAPTF--YT 100
A N LG A + A LVV + RR + + AP T
Sbjct: 183 EVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQRRREAMRAEGAPASPPST 242
Query: 101 YPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVS 160
V EG++ C V G P P W KDG ++T R V E + +L+I
Sbjct: 243 GTRTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCK 302
Query: 161 IEDVGIYRITVENELGRAEASARLEV 186
D G+Y T N +G+ +S + V
Sbjct: 303 QSDRGLYTCTASNLVGQTYSSVLVVV 328
Score = 60.9 bits (141), Expect = 3e-09
Identities = 50/191 (26%), Positives = 81/191 (42%), Gaps = 17/191 (8%)
Query: 10 EFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNC 69
+F+ +V G P P + WF + + A + L+I VT ED G Y SN
Sbjct: 5279 KFQLKVKGYPAPRLYWFKDGQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNA 5338
Query: 70 LGKAKSNACLVVY-----HTRRLSSPGRQMAPTFYTYPFN-KVVEEGENVTFKCAVKGNP 123
+G A S+A L+V + S Q+ P F K V++G ++TF V+G P
Sbjct: 5339 MGAAYSSARLLVRGPDEPEEKPASDVHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGRP 5398
Query: 124 SPWASW---DKDGSII-----TPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENEL 175
P W + + ++ TP + ++ + +L++ + G Y N
Sbjct: 5399 VPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLDVGR---QHQGTYTCIASNAA 5455
Query: 176 GRAEASARLEV 186
G+A SA L V
Sbjct: 5456 GQALCSASLHV 5466
Score = 52.0 bits (119), Expect = 2e-06
Identities = 28/78 (35%), Positives = 40/78 (51%), Gaps = 1/78 (1%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYD-DGTARLKIKQVTAEDEGTYT 63
DG V F+C VTG P P +RWF +++ + + + D G +L I V D G Y
Sbjct: 5139 DGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQLIITAVVPADMGVYR 5198
Query: 64 CEASNCLGKAKSNACLVV 81
C A N +G + + A L V
Sbjct: 5199 CLAENSMGVSSTKAELRV 5216
Score = 48.8 bits (111), Expect = 1e-05
Identities = 25/75 (33%), Positives = 38/75 (50%), Gaps = 2/75 (2%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFE--SSYDDGTARLKIKQVTAEDEGTY 62
+G+ +F C + G P P IRW+ ++ F+ S G L I+ + ED G Y
Sbjct: 6121 EGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLY 6180
Query: 63 TCEASNCLGKAKSNA 77
CE N LG A+++A
Sbjct: 6181 ECELVNRLGSARASA 6195
Score = 48.4 bits (110), Expect = 2e-05
Identities = 26/77 (33%), Positives = 33/77 (42%), Gaps = 1/77 (1%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFE-SSYDDGTARLKIKQVTAEDEGTYTC 64
GD + EC V D RW + D DGT L I + D G YTC
Sbjct: 4912 GDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLGDGTCSLLITGLDRADAGCYTC 4971
Query: 65 EASNCLGKAKSNACLVV 81
+ SN G+ +AC+VV
Sbjct: 4972 QVSNKFGQVTHSACVVV 4988
Score = 44.8 bits (101), Expect = 2e-04
Identities = 48/180 (26%), Positives = 80/180 (44%), Gaps = 20/180 (11%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G TV C+++ ++ W +R F+ + L + + AED G Y CE
Sbjct: 1823 GGTVTLACELSP-ACAEVVWRCGNTQLRVGKRFQMVAEGPVRSLTVLGLRAEDAGEYVCE 1881
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
+ + ++A L V R + F + V EEG TF+C V +PS
Sbjct: 1882 SRD----DHTSAQLTVSVPRVVK---------FMSGLSTVVAEEGGEATFQCVV--SPSD 1926
Query: 126 WA-SWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
A W +DG+++ PS + + + L I ++ +ED G +ITVE E + A+ R+
Sbjct: 1927 VAVVWFRDGALLQPSEKFAISQ-SGASHSLTISDLVLEDAG--QITVEAEGASSSAALRV 1983
Score = 44.4 bits (100), Expect = 3e-04
Identities = 40/163 (24%), Positives = 65/163 (39%), Gaps = 16/163 (9%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G T C+V P ++ W+ + + + T RL ++QV D G Y+CE
Sbjct: 1181 GTTAMLSCEVA-QPQTEVTWYKDGKKLSSSSKVRMEVKGCTRRLVVQQVGKADAGEYSCE 1239
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKV-VEEGENVTFKCAVKGNPS 124
A G+ V ++ P A + N+V E G + T C V
Sbjct: 1240 AG---GQR-------VSFQLHITEPKAVFAKEQLVH--NEVRTEAGASATLSCEV-AQAQ 1286
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIY 167
+W KDG ++ S+++ + E MR L + + D G Y
Sbjct: 1287 TEVTWYKDGKKLSSSSKVRI-EAAGCMRQLVVQQAGQADAGEY 1328
Score = 44.4 bits (100), Expect = 3e-04
Identities = 51/199 (25%), Positives = 84/199 (42%), Gaps = 21/199 (10%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G+ + C+ T D + W + +R A + S++ A+L I T +D G Y C
Sbjct: 3109 EGEDLTLVCE-TSTCDIPVCWTKDGKTLRGSARCQLSHEGHRAQLLITGATLQDSGRYKC 3167
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
EA G A S++ +V H R P R F + V EG T +C + +
Sbjct: 3168 EA----GGACSSS-IVRVHAR----PVR-----FQEALKDLEVLEGGAATLRCVLSSVAA 3213
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
P W +++ P + ++++ E M L + + +D G Y + G SA L
Sbjct: 3214 P-VKWCYGNNVLRPGDKYSLRQ-EGAMLELVVRNLRPQDSGRYSCS----FGDQTTSATL 3267
Query: 185 EVITRSGKFYGGLRAYSAS 203
V +F G LR A+
Sbjct: 3268 TVTALPAQFIGKLRNKEAT 3286
Score = 42.7 bits (96), Expect = 0.001
Identities = 43/185 (23%), Positives = 79/185 (42%), Gaps = 19/185 (10%)
Query: 7 DTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTAR-LKIKQVTAEDEGTYTCE 65
+ VEF C+V+ ++W ++ E + DG L++K VT ED GT +
Sbjct: 4174 EDVEFSCEVSRAGATGVQWCLQGLPLQSNEVTEVAVRDGRIHTLRLKGVTPEDAGTVSFH 4233
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
LG S+A L V R T + + EG++ +F+C +
Sbjct: 4234 ----LGNHASSAQLTV----------RAPEVTILEPLQDVQLSEGQDASFQCRLSRASGQ 4279
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
A W G + + + ++ + +L + +V++ED G TV +G + A+L+
Sbjct: 4280 EARWALGGVPLQANEMNDITVEQGTLHLLTLHKVTLEDAG----TVSFHVGTCSSEAQLK 4335
Query: 186 VITRS 190
V ++
Sbjct: 4336 VTAKN 4340
Score = 41.9 bits (94), Expect = 0.002
Identities = 47/187 (25%), Positives = 80/187 (42%), Gaps = 21/187 (11%)
Query: 8 TVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEAS 67
T F C+ T +P + W +R + S + T RL I + D TYTC+
Sbjct: 2932 TAVFTCK-TEHPAATVTWRKGLLELRASGKHQPSQEGLTLRLTISALEKADSDTYTCD-- 2988
Query: 68 NCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVK-GNPSPW 126
+G+A+S A L+V GR++ + V+EG + TF+C + N P
Sbjct: 2989 --IGQAQSRAQLLV--------QGRRVHIIEDLEDVD--VQEGSSATFRCRISPANYEP- 3035
Query: 127 ASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W D + + + + + +L + +++++D G T+ E G ASA L V
Sbjct: 3036 VHWFLDKTPLHANELNEIDAQPGGYHVLTLRQLALKDSG----TIYFEAGDQRASAALRV 3091
Query: 187 ITRSGKF 193
+ F
Sbjct: 3092 TEKPSVF 3098
Score = 40.7 bits (91), Expect = 0.004
Identities = 46/198 (23%), Positives = 78/198 (39%), Gaps = 21/198 (10%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G F+C V+ + D + WF +++ F S + L I + ED G T
Sbjct: 1912 EGGEATFQCVVSPS-DVAVVWFRDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQITV 1970
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
EA A S+A L V L +++ P + VEE +VT + + P
Sbjct: 1971 EAEG----ASSSAALRVREAPVLFK--KKLEP--------QTVEERSSVTLEVELT-RPW 2015
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
P W ++ + + P + + E L + V D G + ++ + A+L
Sbjct: 2016 PELRWTRNATALAPGKNVEI-HAEGARHRLVLHNVGFADRGFFGCETPDD----KTQAKL 2070
Query: 185 EVITRSGKFYGGLRAYSA 202
V R + GL+A A
Sbjct: 2071 TVEMRQVRLVRGLQAVEA 2088
Score = 40.7 bits (91), Expect = 0.004
Identities = 21/57 (36%), Positives = 31/57 (54%), Gaps = 1/57 (1%)
Query: 12 ECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
ECQV+ +RWF ++ ++ +E D +L I V AEDE TYTC+A +
Sbjct: 2310 ECQVS-RASAQVRWFKGSQELQPGPKYELVSDGLYRKLIISDVHAEDEDTYTCDAGD 2365
Score = 37.9 bits (84), Expect = 0.027
Identities = 44/181 (24%), Positives = 74/181 (40%), Gaps = 21/181 (11%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+ VE C+++ P + W + IR ++ + A L I+ + +D G YTCE
Sbjct: 2841 GEDVELRCELSRAGTP-VHWLKDRKAIRKSQKYDVVCEGTMAMLVIRGASLKDAGEYTCE 2899
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
+KS A L V + A F N VEE F C + +P+
Sbjct: 2900 VE----ASKSTASLHV----------EEKANCFTEELTNLQVEEKGTAVFTCKTE-HPAA 2944
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
+W K + S + ++ +R L I + D Y ++G+A++ A+L
Sbjct: 2945 TVTWRKGLLELRASGKHQPSQEGLTLR-LTISALEKADSDTYTC----DIGQAQSRAQLL 2999
Query: 186 V 186
V
Sbjct: 3000 V 3000
Score = 37.9 bits (84), Expect = 0.027
Identities = 44/180 (24%), Positives = 71/180 (39%), Gaps = 21/180 (11%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGT-ARLKIKQVTAEDEGTYT 63
+G T C+++ + W+ E +RD D S DG L+I+ + AED G Y
Sbjct: 3639 EGATAVLRCELSKMAP--VEWWKGHETLRD-GDRHSLRQDGARCELQIRGLVAEDAGEYL 3695
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
C GK +++A L V R M F N+ EG+ T C +
Sbjct: 3696 C----MCGKERTSAMLTV----------RAMPSKFIEGLRNEEATEGDTATLWCEL-SKA 3740
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
+P W K + R ++++ L+I +++ D G Y E A + R
Sbjct: 3741 AP-VEWRKGHETLRDGDRHSLRQDGSRCE-LQIRGLAVVDAGEYSCVCGQERTSATLTVR 3798
Score = 37.5 bits (83), Expect = 0.036
Identities = 50/200 (25%), Positives = 80/200 (40%), Gaps = 25/200 (12%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGT-ARLKIKQVTAEDEGTYT 63
+G T +C++ N + W +E +RD D S DGT L+I+ + D G Y+
Sbjct: 3551 EGATAVLQCEL--NSAAPVEWRKGSETLRD-GDRYSLRQDGTKCELQIRGLAMADTGEYS 3607
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
C G+ +++A L V R + F N+ EG +C +
Sbjct: 3608 C----VCGQERTSAMLTV----------RALPIKFTEGLRNEEATEGATAVLRCEL-SKM 3652
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
+P W K + R ++++ + L+I + ED G Y G+ SA
Sbjct: 3653 AP-VEWWKGHETLRDGDRHSLRQ-DGARCELQIRGLVAEDAGEYLCM----CGKERTSAM 3706
Query: 184 LEVITRSGKFYGGLRAYSAS 203
L V KF GLR A+
Sbjct: 3707 LTVRAMPSKFIEGLRNEEAT 3726
Score = 36.7 bits (81), Expect = 0.063
Identities = 40/163 (24%), Positives = 65/163 (39%), Gaps = 15/163 (9%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTA-RLKIKQVTAEDEGTYTC 64
G +FEC+ T + W+ + + D GT RL VT +DEGTY+C
Sbjct: 812 GGPAQFECE-TSEAHVHVHWYKDGMELGHSGERFLQEDVGTRHRLVAATVTRQDEGTYSC 870
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
+G+ + L V + + + Q+A E G + T C V
Sbjct: 871 R----VGEDSVDFRLRVSEPKVVFAK-EQLARR------KLQAEAGASATLSCEV-AQAQ 918
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIY 167
+W KDG ++ S+++ + E R L + + D G Y
Sbjct: 919 TEVTWYKDGKKLSSSSKVCM-EATGCTRRLVVQQAGQADAGEY 960
Score = 36.7 bits (81), Expect = 0.063
Identities = 25/82 (30%), Positives = 37/82 (45%), Gaps = 6/82 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWF-HYAE-----VIRDCADFESSYDDGTARLKIKQVTAEDE 59
G ++ F +V G P P + W AE + D + + L + V + +
Sbjct: 5385 GSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLDVGRQHQ 5444
Query: 60 GTYTCEASNCLGKAKSNACLVV 81
GTYTC ASN G+A +A L V
Sbjct: 5445 GTYTCIASNAAGQALCSASLHV 5466
Score = 36.7 bits (81), Expect = 0.063
Identities = 22/79 (27%), Positives = 31/79 (39%)
Query: 108 EEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIY 167
E GE V C V G P P SW KDG + + E + L +D ++ D G Y
Sbjct: 6026 ELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQY 6085
Query: 168 RITVENELGRAEASARLEV 186
+ G ++ V
Sbjct: 6086 MCFAASAAGNCSTLGKILV 6104
Score = 35.5 bits (78), Expect = 0.15
Identities = 41/178 (23%), Positives = 72/178 (40%), Gaps = 19/178 (10%)
Query: 8 TVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEAS 67
T+ +C+V+ +P+ + W + ++ + GT L + V+ ED G YTC
Sbjct: 2663 TLALQCEVS-DPEAHVVWRKDGVQLGPSDKYDFLHTAGTRGLVVHDVSPEDAGLYTCHVG 2721
Query: 68 NCLGKAKSNA-CLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVK-GNPSP 125
+ +A+ L V T+RL + V EGE+ +F+C + + S
Sbjct: 2722 SEETRARVRVHDLHVGITKRLKT---------------MEVLEGESCSFECVLSHESASD 2766
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
A W G + S+R ++ IL + E + D G +V +A R
Sbjct: 2767 PAMWTVGGKTVGSSSRFQA-TRQGRKYILVVREAAPSDAGEVVFSVRGLTSKASLIVR 2823
Score = 35.5 bits (78), Expect = 0.15
Identities = 46/190 (24%), Positives = 73/190 (38%), Gaps = 24/190 (12%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGT-ARLKIKQVTAEDEGTYT 63
+G T +C+++ + W +E +R D S DGT L+I ++ D G Y+
Sbjct: 3815 EGATAVLQCELS--KAAPVEWRKGSETLRG-GDRYSLRQDGTRCELQIHGLSVADTGEYS 3871
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
C G+ +++A L V R P F + EEG T +C + P
Sbjct: 3872 C----VCGQERTSATLTV----------RAPQPVFREPLQSLQAEEGSTATLQCEL-SEP 3916
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
+ W K G + + R + L + ++ ED G Y T G SA
Sbjct: 3917 TATVVWSKGGLQLQANGR-REPRLQGCTAELVLQDLQREDTGEYTCT----CGSQATSAT 3971
Query: 184 LEVITRSGKF 193
L V +F
Sbjct: 3972 LTVTAAPVRF 3981
Score = 34.7 bits (76), Expect = 0.26
Identities = 16/64 (25%), Positives = 29/64 (45%), Gaps = 1/64 (1%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G T C+++ + W + + CA ++ D A L ++ V ED G YTC
Sbjct: 3992 EGGTAHLCCELS-RAGASVEWRKGSLQLFPCAKYQMVQDGAAAELLVRGVEQEDAGDYTC 4050
Query: 65 EASN 68
+ +
Sbjct: 4051 DTGH 4054
Score = 32.7 bits (71), Expect = 1.0
Identities = 42/194 (21%), Positives = 74/194 (38%), Gaps = 23/194 (11%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G T C+++ + W +E +RD + D L+I+ + D Y+C
Sbjct: 3287 EGATATLRCELS--KAAPVEWRKGSETLRDGDRYCLRQDGAMCELQIRGLAMVDAAEYSC 3344
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
G+ +++A L + R M F ++ EG T +C + +
Sbjct: 3345 ----VCGEERTSASLTI----------RPMPAHFIGRLRHQESIEGATATLRCEL-SKAA 3389
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
P W K + R ++++ + L+I +++ D G Y G SA L
Sbjct: 3390 P-VEWRKGRESLRDGDRHSLRQDGAVCE-LQICGLAVADAGEYSCV----CGEERTSATL 3443
Query: 185 EVITRSGKFYGGLR 198
V KF GLR
Sbjct: 3444 TVKALPAKFTEGLR 3457
Score = 31.9 bits (69), Expect = 1.8
Identities = 23/71 (32%), Positives = 32/71 (45%), Gaps = 2/71 (2%)
Query: 108 EEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIY 167
EE + +C V +P W KDG + PS + R L + +VS ED G+Y
Sbjct: 2659 EERGTLALQCEVS-DPEAHVVWRKDGVQLGPSDKYDFLHTAGT-RGLVVHDVSPEDAGLY 2716
Query: 168 RITVENELGRA 178
V +E RA
Sbjct: 2717 TCHVGSEETRA 2727
Score = 31.5 bits (68), Expect = 2.4
Identities = 15/59 (25%), Positives = 27/59 (45%), Gaps = 1/59 (1%)
Query: 7 DTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
++ F C+V P + WF + A + + RL ++ V+A+D+ Y CE
Sbjct: 348 ESATFLCEVP-QPSTEAAWFKEETRLWASAKYGIEEEGTERRLTVRNVSADDDAVYICE 405
Score = 30.7 bits (66), Expect = 4.2
Identities = 21/92 (22%), Positives = 36/92 (39%), Gaps = 1/92 (1%)
Query: 92 RQMAPTFYTYPFNKV-VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEI 150
+Q +++ F + G+ + +C V A W KDG +T + + +
Sbjct: 4893 KQQEGPMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLGDG 4952
Query: 151 MRILEIDEVSIEDVGIYRITVENELGRAEASA 182
L I + D G Y V N+ G+ SA
Sbjct: 4953 TCSLLITGLDRADAGCYTCQVSNKFGQVTHSA 4984
Score = 30.3 bits (65), Expect = 5.5
Identities = 40/180 (22%), Positives = 66/180 (36%), Gaps = 17/180 (9%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G T +C+++ P + W ++ E TA L ++ + ED G YTC
Sbjct: 3903 EGSTATLQCELS-EPTATVVWSKGGLQLQANGRREPRLQGCTAELVLQDLQREDTGEYTC 3961
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
C G ++A L V ++P R F ++ V+EG C
Sbjct: 3962 ---TC-GSQATSATLTV-----TAAPVR-----FLRELQHQEVDEG-GTAHLCCELSRAG 4006
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
W K + P A+ + + +L + V ED G Y + A S R+
Sbjct: 4007 ASVEWRKGSLQLFPCAKYQMVQDGAAAELL-VRGVEQEDAGDYTCDTGHTQSMASLSVRV 4065
Score = 29.9 bits (64), Expect = 7.3
Identities = 44/195 (22%), Positives = 73/195 (37%), Gaps = 20/195 (10%)
Query: 23 IRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLGKAKSNACLVVY 82
++W+ + F+ S + A L+I ++ D G Y C+A G A S+ + V
Sbjct: 2499 VQWYKDDTPLSPSEKFKMSLEGQMAELRILRLMPADAGVYRCQA----GSAHSSTEVTV- 2553
Query: 83 HTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARI 142
R ++ G + EEG +F C + + W +G + +
Sbjct: 2554 EAREVTVTGPLQDA--------EATEEGW-ASFSCEL-SHEDEEVEWSLNGMPLYNDSFH 2603
Query: 143 TVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVITRSGKFYGGLRAYSA 202
+ K L + + D GI R + + SARLEV + F L SA
Sbjct: 2604 EISHKGR-RHTLVLKSIQRADAGIVRASSL----KVSTSARLEVRVKPVVFLKALDDLSA 2658
Query: 203 SPRKCLSYRRRPSTP 217
R L+ + S P
Sbjct: 2659 EERGTLALQCEVSDP 2673
Score = 29.9 bits (64), Expect = 7.3
Identities = 19/59 (32%), Positives = 25/59 (42%), Gaps = 1/59 (1%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
G+ V E +V ++ W E I+ FE L IK TAED+G Y C
Sbjct: 4638 GEDVSLELEVVAEAG-EVIWHKGMERIQPGGRFEVVSQGRQQMLVIKGFTAEDQGEYHC 4695
>AJ002535-1|CAC44768.1| 6620|Homo sapiens obscurin protein.
Length = 6620
Score = 96.3 bits (229), Expect = 7e-20
Identities = 67/221 (30%), Positives = 93/221 (42%), Gaps = 14/221 (6%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G CQ+ GNP P + W + + A F + D RL I + D G Y C
Sbjct: 24 GKDATLSCQIVGNPTPQVSWEKDQQPVTAGARFRLAQDGDLYRLTILDLALGDSGQYVCR 83
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A N +G+A + L V + + AP F P + V EG TF+C V G+P P
Sbjct: 84 ARNAIGEAFAAVGLQV----DAEAACAEQAPHFLLRPTSIRVREGSEATFRCRVGGSPRP 139
Query: 126 WASWDKDGSII--TPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
SW KDG + R+ V+E E L I D G Y + EN LG A A+A
Sbjct: 140 AVSWSKDGRRLGEPDGPRVRVEELGE-ASALRIRAARPRDGGTYEVRAENPLGAASAAAA 198
Query: 184 L-------EVITRSGKFYGGLRAYSASPRKCLSYRRRPSTP 217
L + +R G L A+ R+ + P++P
Sbjct: 199 LVVDSDAADTASRPGTSTAALLAHLQRRREAMRAEGAPASP 239
Score = 93.5 bits (222), Expect = 5e-19
Identities = 56/183 (30%), Positives = 86/183 (46%), Gaps = 13/183 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIR-DCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
G+TV+ C+VTG P P I W+ + ++ D DG+ L + +T D G Y C
Sbjct: 6028 GETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQYMC 6087
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
A++ G + ++V Q+ P F EGE+ F C ++G P
Sbjct: 6088 FAASAAGNCSTLGKILV-----------QVPPRFVNKVLASPFVEGEDAQFTCTIEGAPY 6136
Query: 125 PWASWDKDGSIITPSARI-TVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
P W KDG+++T + T+ E + +L I S ED+G+Y + N LG A ASA
Sbjct: 6137 PQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAE 6196
Query: 184 LEV 186
L +
Sbjct: 6197 LRI 6199
Score = 64.1 bits (149), Expect = 4e-10
Identities = 33/100 (33%), Positives = 52/100 (52%), Gaps = 1/100 (1%)
Query: 87 LSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKE 146
+ P AP F T P VV G++ T C + GNP+P SW+KD +T AR + +
Sbjct: 1 MDQPQFSGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVTAGARFRLAQ 60
Query: 147 KEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
++ R+ +D +++ D G Y N +G A A+ L+V
Sbjct: 61 DGDLYRLTILD-LALGDSGQYVCRARNAIGEAFAAVGLQV 99
Score = 62.5 bits (145), Expect = 1e-09
Identities = 32/92 (34%), Positives = 45/92 (48%)
Query: 95 APTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRIL 154
AP F T N+ V++G V+F C V G P P W KDG ++ + E ++ L
Sbjct: 5125 APVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQL 5184
Query: 155 EIDEVSIEDVGIYRITVENELGRAEASARLEV 186
I V D+G+YR EN +G + A L V
Sbjct: 5185 IITAVVPADMGVYRCLAENSMGVSSTKAELRV 5216
Score = 62.1 bits (144), Expect = 1e-09
Identities = 50/165 (30%), Positives = 74/165 (44%), Gaps = 15/165 (9%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTAR--LKIKQVTAEDEGTY 62
+G C VTG P P+ W +++ + Y+D LKI D G Y
Sbjct: 251 EGKHARLSCYVTGEPKPETVWKKDGQLVTE-GRRHVVYEDAQENFVLKILFCKQSDRGLY 309
Query: 63 TCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGN 122
TC ASN +G+ S+ +VV R+ A F + V E E+ TF C V
Sbjct: 310 TCTASNLVGQTYSSVLVVV----------REPAVPFKKRLQDLEVREKESATFLCEVP-Q 358
Query: 123 PSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIY 167
PS A+W K+ + + SA+ + E+E R L + VS +D +Y
Sbjct: 359 PSTEAAWFKEETRLWASAKYGI-EEEGTERRLTVRNVSADDDAVY 402
Score = 60.9 bits (141), Expect = 3e-09
Identities = 56/206 (27%), Positives = 82/206 (39%), Gaps = 24/206 (11%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDD-GTAR-LKIKQVTAEDEGTY 62
+G F C+V G+P P + W + + ++ G A L+I+ D GTY
Sbjct: 123 EGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGTY 182
Query: 63 TCEASNCLGKAKSNACLVV--------------------YHTRRLSSPGRQMAPTF--YT 100
A N LG A + A LVV + RR + + AP T
Sbjct: 183 EVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQRRREAMRAEGAPASPPST 242
Query: 101 YPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVS 160
V EG++ C V G P P W KDG ++T R V E + +L+I
Sbjct: 243 GTRTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCK 302
Query: 161 IEDVGIYRITVENELGRAEASARLEV 186
D G+Y T N +G+ +S + V
Sbjct: 303 QSDRGLYTCTASNLVGQTYSSVLVVV 328
Score = 60.9 bits (141), Expect = 3e-09
Identities = 50/191 (26%), Positives = 81/191 (42%), Gaps = 17/191 (8%)
Query: 10 EFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNC 69
+F+ +V G P P + WF + + A + L+I VT ED G Y SN
Sbjct: 5279 KFQLKVKGYPAPRLYWFKDGQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNA 5338
Query: 70 LGKAKSNACLVVY-----HTRRLSSPGRQMAPTFYTYPFN-KVVEEGENVTFKCAVKGNP 123
+G A S+A L+V + S Q+ P F K V++G ++TF V+G P
Sbjct: 5339 MGAAYSSARLLVRGPDEPEEKPASDVHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGRP 5398
Query: 124 SPWASW---DKDGSII-----TPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENEL 175
P W + + ++ TP + ++ + +L++ + G Y N
Sbjct: 5399 VPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLDVGR---QHQGTYTCIASNAA 5455
Query: 176 GRAEASARLEV 186
G+A SA L V
Sbjct: 5456 GQALCSASLHV 5466
Score = 52.0 bits (119), Expect = 2e-06
Identities = 28/78 (35%), Positives = 40/78 (51%), Gaps = 1/78 (1%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYD-DGTARLKIKQVTAEDEGTYT 63
DG V F+C VTG P P +RWF +++ + + + D G +L I V D G Y
Sbjct: 5139 DGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQLIITAVVPADMGVYR 5198
Query: 64 CEASNCLGKAKSNACLVV 81
C A N +G + + A L V
Sbjct: 5199 CLAENSMGVSSTKAELRV 5216
Score = 48.8 bits (111), Expect = 1e-05
Identities = 25/75 (33%), Positives = 38/75 (50%), Gaps = 2/75 (2%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFE--SSYDDGTARLKIKQVTAEDEGTY 62
+G+ +F C + G P P IRW+ ++ F+ S G L I+ + ED G Y
Sbjct: 6121 EGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLY 6180
Query: 63 TCEASNCLGKAKSNA 77
CE N LG A+++A
Sbjct: 6181 ECELVNRLGSARASA 6195
Score = 48.4 bits (110), Expect = 2e-05
Identities = 26/77 (33%), Positives = 33/77 (42%), Gaps = 1/77 (1%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFE-SSYDDGTARLKIKQVTAEDEGTYTC 64
GD + EC V D RW + D DGT L I + D G YTC
Sbjct: 4912 GDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLGDGTCSLLIAGLDRADAGCYTC 4971
Query: 65 EASNCLGKAKSNACLVV 81
+ SN G+ +AC+VV
Sbjct: 4972 QVSNKFGQVTHSACVVV 4988
Score = 44.4 bits (100), Expect = 3e-04
Identities = 40/163 (24%), Positives = 65/163 (39%), Gaps = 16/163 (9%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G T C+V P ++ W+ + + + T RL ++QV D G Y+CE
Sbjct: 1181 GTTAMLSCEVA-QPQTEVTWYKDGKKLSSSSKVRMEVKGCTRRLVVQQVGKADAGEYSCE 1239
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKV-VEEGENVTFKCAVKGNPS 124
A G+ V ++ P A + N+V E G + T C V
Sbjct: 1240 AG---GQR-------VSFQLHITEPKAVFAKEQLVH--NEVRTEAGASATLSCEV-AQAQ 1286
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIY 167
+W KDG ++ S+++ + E MR L + + D G Y
Sbjct: 1287 TEVTWYKDGKKLSSSSKVRI-EAAGCMRQLVVQQAGQADAGEY 1328
Score = 43.6 bits (98), Expect = 6e-04
Identities = 43/143 (30%), Positives = 68/143 (47%), Gaps = 20/143 (13%)
Query: 44 DGTAR-LKIKQVTAEDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYP 102
+G R L + + AED G Y CE+ + ++A L V R + F +
Sbjct: 1859 EGPVRSLTVLGLRAEDAGEYVCESRD----DHTSAQLTVSVPRVVK---------FMSGL 1905
Query: 103 FNKVVEEGENVTFKCAVKGNPSPWA-SWDKDGSIITPSARITVKEKEEIMRILEIDEVSI 161
V EEG TF+C V +PS A W +DG+++ PS + + + L I ++ +
Sbjct: 1906 STVVAEEGGEATFQCVV--SPSDVAVVWFRDGALLQPSEKFAISQ-SGASHSLTISDLVL 1962
Query: 162 EDVGIYRITVENELGRAEASARL 184
ED G +ITVE E + A+ R+
Sbjct: 1963 EDAG--QITVEAEGASSSAALRV 1983
Score = 43.6 bits (98), Expect = 6e-04
Identities = 51/199 (25%), Positives = 84/199 (42%), Gaps = 21/199 (10%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G+ + C+ T D + W + +R A + S++ A+L I T +D G Y C
Sbjct: 3109 EGEDLTLVCE-TSTCDIPMCWTKDGKTLRGSARCQLSHEGHRAQLLITGATLQDSGRYKC 3167
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
EA G A S++ +V H R P R F + V EG T +C + +
Sbjct: 3168 EA----GGACSSS-IVRVHAR----PVR-----FQEALKDLEVLEGGAATLRCVLSSVAA 3213
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
P W +++ P + ++++ E M L + + +D G Y + G SA L
Sbjct: 3214 P-VKWCYGNNVLRPGDKYSLRQ-EGAMLELVVRNLRPQDSGRYSCS----FGDQTTSATL 3267
Query: 185 EVITRSGKFYGGLRAYSAS 203
V +F G LR A+
Sbjct: 3268 TVTALPAQFIGKLRNKEAT 3286
Score = 42.7 bits (96), Expect = 0.001
Identities = 43/185 (23%), Positives = 79/185 (42%), Gaps = 19/185 (10%)
Query: 7 DTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTAR-LKIKQVTAEDEGTYTCE 65
+ VEF C+V+ ++W ++ E + DG L++K VT ED GT +
Sbjct: 4174 EDVEFSCEVSRAGATGVQWCLQGLPLQSNEVTEVAVRDGRIHTLRLKGVTPEDAGTVSFH 4233
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
LG S+A L V R T + + EG++ +F+C +
Sbjct: 4234 ----LGNHASSAQLTV----------RAPEVTILEPLQDVQLSEGQDASFQCRLSRASGQ 4279
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
A W G + + + ++ + +L + +V++ED G TV +G + A+L+
Sbjct: 4280 EARWALGGVPLQANEMNDITVEQGTLHLLTLHKVTLEDAG----TVSFHVGTCSSEAQLK 4335
Query: 186 VITRS 190
V ++
Sbjct: 4336 VTAKN 4340
Score = 41.9 bits (94), Expect = 0.002
Identities = 47/187 (25%), Positives = 80/187 (42%), Gaps = 21/187 (11%)
Query: 8 TVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEAS 67
T F C+ T +P + W +R + S + T RL I + D TYTC+
Sbjct: 2932 TAVFTCK-TEHPAATVTWRKGLLELRASGKHQPSQEGLTLRLTISALEKADSDTYTCD-- 2988
Query: 68 NCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVK-GNPSPW 126
+G+A+S A L+V GR++ + V+EG + TF+C + N P
Sbjct: 2989 --IGQAQSRAQLLV--------QGRRVHIIEDLEDVD--VQEGSSATFRCRISPANYEP- 3035
Query: 127 ASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W D + + + + + +L + +++++D G T+ E G ASA L V
Sbjct: 3036 VHWFLDKTPLHANELNEIDAQPGGYHVLTLRQLALKDSG----TIYFEAGDQRASAALRV 3091
Query: 187 ITRSGKF 193
+ F
Sbjct: 3092 TEKPSVF 3098
Score = 40.7 bits (91), Expect = 0.004
Identities = 46/198 (23%), Positives = 78/198 (39%), Gaps = 21/198 (10%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G F+C V+ + D + WF +++ F S + L I + ED G T
Sbjct: 1912 EGGEATFQCVVSPS-DVAVVWFRDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQITV 1970
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
EA A S+A L V L +++ P + VEE +VT + + P
Sbjct: 1971 EAEG----ASSSAALRVREAPVLFK--KKLEP--------QTVEERSSVTLEVELT-RPW 2015
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
P W ++ + + P + + E L + V D G + ++ + A+L
Sbjct: 2016 PELRWTRNATALAPGKNVEI-HAEGARHRLVLHNVGFADRGFFGCETPDD----KTQAKL 2070
Query: 185 EVITRSGKFYGGLRAYSA 202
V R + GL+A A
Sbjct: 2071 TVEMRQVRLVRGLQAVEA 2088
Score = 40.7 bits (91), Expect = 0.004
Identities = 21/57 (36%), Positives = 31/57 (54%), Gaps = 1/57 (1%)
Query: 12 ECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
ECQV+ +RWF ++ ++ +E D +L I V AEDE TYTC+A +
Sbjct: 2310 ECQVS-RASAQVRWFKGSQELQPGPKYELVSDGLYRKLIISDVHAEDEDTYTCDAGD 2365
Score = 37.9 bits (84), Expect = 0.027
Identities = 44/181 (24%), Positives = 74/181 (40%), Gaps = 21/181 (11%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+ VE C+++ P + W + IR ++ + A L I+ + +D G YTCE
Sbjct: 2841 GEDVELRCELSRAGTP-VHWLKDRKAIRKSQKYDVVCEGTMAMLVIRGASLKDAGEYTCE 2899
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
+KS A L V + A F N VEE F C + +P+
Sbjct: 2900 VE----ASKSTASLHV----------EEKANCFTEELTNLQVEEKGTAVFTCKTE-HPAA 2944
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
+W K + S + ++ +R L I + D Y ++G+A++ A+L
Sbjct: 2945 TVTWRKGLLELRASGKHQPSQEGLTLR-LTISALEKADSDTYTC----DIGQAQSRAQLL 2999
Query: 186 V 186
V
Sbjct: 3000 V 3000
Score = 37.9 bits (84), Expect = 0.027
Identities = 44/180 (24%), Positives = 71/180 (39%), Gaps = 21/180 (11%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGT-ARLKIKQVTAEDEGTYT 63
+G T C+++ + W+ E +RD D S DG L+I+ + AED G Y
Sbjct: 3639 EGATAVLRCELSKMAP--VEWWKGHETLRD-GDRHSLRQDGARCELQIRGLVAEDAGEYL 3695
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
C GK +++A L V R M F N+ EG+ T C +
Sbjct: 3696 C----MCGKERTSAMLTV----------RAMPSKFIEGLRNEEATEGDTATLWCEL-SKA 3740
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
+P W K + R ++++ L+I +++ D G Y E A + R
Sbjct: 3741 AP-VEWRKGHETLRDGDRHSLRQDGSRCE-LQIRGLAVVDAGEYSCVCGQERTSATLTVR 3798
Score = 37.5 bits (83), Expect = 0.036
Identities = 50/200 (25%), Positives = 80/200 (40%), Gaps = 25/200 (12%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGT-ARLKIKQVTAEDEGTYT 63
+G T +C++ N + W +E +RD D S DGT L+I+ + D G Y+
Sbjct: 3551 EGATAVLQCEL--NSAAPVEWRKGSETLRD-GDRYSLRQDGTKCELQIRGLAMADTGEYS 3607
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
C G+ +++A L V R + F N+ EG +C +
Sbjct: 3608 C----VCGQERTSAMLTV----------RALPIKFTEGLRNEEATEGATAVLRCEL-SKM 3652
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
+P W K + R ++++ + L+I + ED G Y G+ SA
Sbjct: 3653 AP-VEWWKGHETLRDGDRHSLRQ-DGARCELQIRGLVAEDAGEYLCM----CGKERTSAM 3706
Query: 184 LEVITRSGKFYGGLRAYSAS 203
L V KF GLR A+
Sbjct: 3707 LTVRAMPSKFIEGLRNEEAT 3726
Score = 36.7 bits (81), Expect = 0.063
Identities = 40/163 (24%), Positives = 65/163 (39%), Gaps = 15/163 (9%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTA-RLKIKQVTAEDEGTYTC 64
G +FEC+ T + W+ + + D GT RL VT +DEGTY+C
Sbjct: 812 GGPAQFECE-TSEAHVHVHWYKDGMELGHSGERFLQEDVGTRHRLVAATVTRQDEGTYSC 870
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
+G+ + L V + + + Q+A E G + T C V
Sbjct: 871 R----VGEDSVDFRLRVSEPKVVFAK-EQLARR------KLQAEAGASATLSCEV-AQAQ 918
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIY 167
+W KDG ++ S+++ + E R L + + D G Y
Sbjct: 919 TEVTWYKDGKKLSSSSKVCM-EATGCTRRLVVQQAGQADAGEY 960
Score = 36.7 bits (81), Expect = 0.063
Identities = 25/82 (30%), Positives = 37/82 (45%), Gaps = 6/82 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWF-HYAE-----VIRDCADFESSYDDGTARLKIKQVTAEDE 59
G ++ F +V G P P + W AE + D + + L + V + +
Sbjct: 5385 GSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLDVGRQHQ 5444
Query: 60 GTYTCEASNCLGKAKSNACLVV 81
GTYTC ASN G+A +A L V
Sbjct: 5445 GTYTCIASNAAGQALCSASLHV 5466
Score = 36.7 bits (81), Expect = 0.063
Identities = 22/79 (27%), Positives = 31/79 (39%)
Query: 108 EEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIY 167
E GE V C V G P P SW KDG + + E + L +D ++ D G Y
Sbjct: 6026 ELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQY 6085
Query: 168 RITVENELGRAEASARLEV 186
+ G ++ V
Sbjct: 6086 MCFAASAAGNCSTLGKILV 6104
Score = 35.5 bits (78), Expect = 0.15
Identities = 41/178 (23%), Positives = 72/178 (40%), Gaps = 19/178 (10%)
Query: 8 TVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEAS 67
T+ +C+V+ +P+ + W + ++ + GT L + V+ ED G YTC
Sbjct: 2663 TLALQCEVS-DPEAHVVWRKDGVQLGPSDKYDFLHTAGTRGLVVHDVSPEDAGLYTCHVG 2721
Query: 68 NCLGKAKSNA-CLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVK-GNPSP 125
+ +A+ L V T+RL + V EGE+ +F+C + + S
Sbjct: 2722 SEETRARVRVHDLHVGITKRLKT---------------MEVLEGESCSFECVLSHESASD 2766
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
A W G + S+R ++ IL + E + D G +V +A R
Sbjct: 2767 PAMWTVGGKTVGSSSRFQA-TRQGRKYILVVREAAPSDAGEVVFSVRGLTSKASLIVR 2823
Score = 35.5 bits (78), Expect = 0.15
Identities = 46/190 (24%), Positives = 73/190 (38%), Gaps = 24/190 (12%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGT-ARLKIKQVTAEDEGTYT 63
+G T +C+++ + W +E +R D S DGT L+I ++ D G Y+
Sbjct: 3815 EGATAVLQCELS--KAAPVEWRKGSETLRG-GDRYSLRQDGTRCELQIHGLSVADTGEYS 3871
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
C G+ +++A L V R P F + EEG T +C + P
Sbjct: 3872 C----VCGQERTSATLTV----------RAPQPVFREPLQSLQAEEGSTATLQCEL-SEP 3916
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
+ W K G + + R + L + ++ ED G Y T G SA
Sbjct: 3917 TATVVWSKGGLQLQANGR-REPRLQGCTAELVLQDLQREDTGEYTCT----CGSQATSAT 3971
Query: 184 LEVITRSGKF 193
L V +F
Sbjct: 3972 LTVTAAPVRF 3981
Score = 34.7 bits (76), Expect = 0.26
Identities = 16/64 (25%), Positives = 29/64 (45%), Gaps = 1/64 (1%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G T C+++ + W + + CA ++ D A L ++ V ED G YTC
Sbjct: 3992 EGGTAHLCCELS-RAGASVEWRKGSLQLFPCAKYQMVQDGAAAELLVRGVEQEDAGDYTC 4050
Query: 65 EASN 68
+ +
Sbjct: 4051 DTGH 4054
Score = 33.1 bits (72), Expect = 0.78
Identities = 42/194 (21%), Positives = 74/194 (38%), Gaps = 23/194 (11%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G T C+++ + W +E +RD + D L+I+ + D Y+C
Sbjct: 3287 EGATATLRCELSKTAP--VEWRKGSETLRDGDRYCLRQDGAMCELQIRGLAMVDAAEYSC 3344
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
G+ +++A L + R M F ++ EG T +C + +
Sbjct: 3345 ----VCGEERTSASLTI----------RPMPAHFIGRLRHQESIEGATATLRCEL-SKAA 3389
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
P W K + R ++++ + L+I +++ D G Y G SA L
Sbjct: 3390 P-VEWRKGRESLRDGDRHSLRQDGAVCE-LQICGLAVADAGEYSCV----CGEERTSATL 3443
Query: 185 EVITRSGKFYGGLR 198
V KF GLR
Sbjct: 3444 TVKALPAKFTEGLR 3457
Score = 31.9 bits (69), Expect = 1.8
Identities = 23/71 (32%), Positives = 32/71 (45%), Gaps = 2/71 (2%)
Query: 108 EEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIY 167
EE + +C V +P W KDG + PS + R L + +VS ED G+Y
Sbjct: 2659 EERGTLALQCEVS-DPEAHVVWRKDGVQLGPSDKYDFLHTAGT-RGLVVHDVSPEDAGLY 2716
Query: 168 RITVENELGRA 178
V +E RA
Sbjct: 2717 TCHVGSEETRA 2727
Score = 31.5 bits (68), Expect = 2.4
Identities = 15/59 (25%), Positives = 27/59 (45%), Gaps = 1/59 (1%)
Query: 7 DTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
++ F C+V P + WF + A + + RL ++ V+A+D+ Y CE
Sbjct: 348 ESATFLCEVP-QPSTEAAWFKEETRLWASAKYGIEEEGTERRLTVRNVSADDDAVYICE 405
Score = 30.3 bits (65), Expect = 5.5
Identities = 40/180 (22%), Positives = 66/180 (36%), Gaps = 17/180 (9%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G T +C+++ P + W ++ E TA L ++ + ED G YTC
Sbjct: 3903 EGSTATLQCELS-EPTATVVWSKGGLQLQANGRREPRLQGCTAELVLQDLQREDTGEYTC 3961
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
C G ++A L V ++P R F ++ V+EG C
Sbjct: 3962 ---TC-GSQATSATLTV-----TAAPVR-----FLRELQHQEVDEG-GTAHLCCELSRAG 4006
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
W K + P A+ + + +L + V ED G Y + A S R+
Sbjct: 4007 ASVEWRKGSLQLFPCAKYQMVQDGAAAELL-VRGVEQEDAGDYTCDTGHTQSMASLSVRV 4065
Score = 30.3 bits (65), Expect = 5.5
Identities = 21/92 (22%), Positives = 36/92 (39%), Gaps = 1/92 (1%)
Query: 92 RQMAPTFYTYPFNKV-VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEI 150
+Q +++ F + G+ + +C V A W KDG +T + + +
Sbjct: 4893 KQQEGPMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLGDG 4952
Query: 151 MRILEIDEVSIEDVGIYRITVENELGRAEASA 182
L I + D G Y V N+ G+ SA
Sbjct: 4953 TCSLLIAGLDRADAGCYTCQVSNKFGQVTHSA 4984
Score = 29.9 bits (64), Expect = 7.3
Identities = 44/195 (22%), Positives = 73/195 (37%), Gaps = 20/195 (10%)
Query: 23 IRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLGKAKSNACLVVY 82
++W+ + F+ S + A L+I ++ D G Y C+A G A S+ + V
Sbjct: 2499 VQWYKDDTPLSPSEKFKMSLEGQMAELRILRLMPADAGVYRCQA----GSAHSSTEVTV- 2553
Query: 83 HTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARI 142
R ++ G + EEG +F C + + W +G + +
Sbjct: 2554 EAREVTVTGPLQDA--------EATEEGW-ASFSCEL-SHEDEEVEWSLNGMPLYNDSFH 2603
Query: 143 TVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVITRSGKFYGGLRAYSA 202
+ K L + + D GI R + + SARLEV + F L SA
Sbjct: 2604 EISHKGR-RHTLVLKSIQRADAGIVRASSL----KVSTSARLEVRVKPVVFLKALDDLSA 2658
Query: 203 SPRKCLSYRRRPSTP 217
R L+ + S P
Sbjct: 2659 EERGTLALQCEVSDP 2673
Score = 29.9 bits (64), Expect = 7.3
Identities = 19/59 (32%), Positives = 25/59 (42%), Gaps = 1/59 (1%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
G+ V E +V ++ W E I+ FE L IK TAED+G Y C
Sbjct: 4638 GEDVSLELEVVAEAG-EVIWHKGMERIQPGGRFEVVSQGRQQMLVIKGFTAEDQGEYHC 4695
>U48959-1|AAC18423.2| 1914|Homo sapiens myosin light chain kinase
protein.
Length = 1914
Score = 95.5 bits (227), Expect = 1e-19
Identities = 55/189 (29%), Positives = 87/189 (46%), Gaps = 8/189 (4%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
DG V QV+GNP P++ W H I++ DF L I++V ED GTYTC
Sbjct: 636 DGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLWIQEVFPEDTGTYTC 695
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
EA N G+ ++ A L V P P F + P + G++V CA+ G+P
Sbjct: 696 EAWNSAGEVRTQAVLTV------QEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPF 749
Query: 125 PWASWDKDG-SIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
P W +DG ++ + V + E++ ++ + +V G Y I ++N +G
Sbjct: 750 PTVHWLRDGKALCKDTGHFEVLQNEDVFTLV-LKKVQPWHAGQYEILLKNRVGECSCQVS 808
Query: 184 LEVITRSGK 192
L + S +
Sbjct: 809 LMLQNSSAR 817
Score = 89.8 bits (213), Expect = 6e-18
Identities = 68/206 (33%), Positives = 95/206 (46%), Gaps = 25/206 (12%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYD-DGTARLKIKQVTAEDEGTYT 63
+G T +FE +V G P+P + W + I F GT L I V ED G YT
Sbjct: 46 EGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYT 105
Query: 64 CEASNCLGKAKSNACLVVYHT--RRLSSP------GRQMA---------------PTFYT 100
CEA+N G + L V + ++L P G + + P F T
Sbjct: 106 CEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSASAVETRPSIWGECPPKFAT 165
Query: 101 YPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVS 160
VV+EG+ F C + G P P +W K + PSAR++V EK M++LEI V+
Sbjct: 166 KLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNG-MQVLEIHGVN 224
Query: 161 IEDVGIYRITVENELGRAEASARLEV 186
+DVG+Y V N G+A SA L +
Sbjct: 225 QDDVGVYTCLVVNGSGKASMSAELSI 250
Score = 85.0 bits (201), Expect = 2e-16
Identities = 59/183 (32%), Positives = 88/183 (48%), Gaps = 10/183 (5%)
Query: 5 DGDTVEFECQVTGNPDPDIRWF-HYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYT 63
+ TV+F C+V+G P P++ WF V R E D G+ L + + D GTY+
Sbjct: 427 ENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYS 486
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
C ASN G+ +C RL+ ++AP+F + + V EG++ +C+V+G P
Sbjct: 487 CTASNAQGQV---SCSWTLQVERLAV--MEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTP 541
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
P +W +G I AR T E + L I + ED G Y EN LG+ SA
Sbjct: 542 VPRITWLLNGQPI-QYARSTC---EAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAW 597
Query: 184 LEV 186
+ V
Sbjct: 598 VTV 600
Score = 80.2 bits (189), Expect = 5e-15
Identities = 60/190 (31%), Positives = 79/190 (41%), Gaps = 12/190 (6%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G +C V G P P I W + I+ S+ + G A L I+ ED GTYTC
Sbjct: 527 EGQDFVLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGTYTC 583
Query: 65 EASNCLGKAKSNACLVVYHTR--RLS------SPGRQMAPTFYTYPFNKVVEEGENVTFK 116
A N LG+ +A + V+ + R S +P + AP F + V +G VT
Sbjct: 584 LAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMT 643
Query: 117 CAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG 176
V GNP P W +G+ I S E+ L I EV ED G Y N G
Sbjct: 644 VQVSGNPPPEVIWLHNGNEIQESEDFHF-EQRGTQHSLWIQEVFPEDTGTYTCEAWNSAG 702
Query: 177 RAEASARLEV 186
A L V
Sbjct: 703 EVRTQAVLTV 712
Score = 69.3 bits (162), Expect = 1e-11
Identities = 31/78 (39%), Positives = 45/78 (57%), Gaps = 1/78 (1%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYD-DGTARLKIKQVTAEDEGTYT 63
+G F+C++ G PDP++ WF + IR+ F+ YD DG L I V +D+ YT
Sbjct: 1822 EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 1881
Query: 64 CEASNCLGKAKSNACLVV 81
C+A N LG+A A L+V
Sbjct: 1882 CKAVNSLGEATCTAELIV 1899
Score = 45.2 bits (102), Expect = 2e-04
Identities = 30/101 (29%), Positives = 41/101 (40%)
Query: 86 RLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVK 145
R+ S AP F P N ++EG F+ V+G P P +W ++G IT R +
Sbjct: 23 RVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLD 82
Query: 146 EKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
L I V ED G Y N G + + L V
Sbjct: 83 CGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
Score = 44.0 bits (99), Expect = 4e-04
Identities = 24/98 (24%), Positives = 47/98 (47%), Gaps = 1/98 (1%)
Query: 89 SPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKE 148
S + AP F + V EG+ + +C V +P W +G + + I + ++
Sbjct: 1091 SESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEG 1150
Query: 149 EIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
+ + I++ ED G+Y+ +N+ G+AE S ++ V
Sbjct: 1151 SLCSV-SIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 1187
Score = 43.2 bits (97), Expect = 7e-04
Identities = 27/104 (25%), Positives = 47/104 (45%), Gaps = 2/104 (1%)
Query: 85 RRLSSPGRQMA--PTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARI 142
RR+ G++ + P F + P ++ V+E + V F+C V G P P +W +G+ +
Sbjct: 401 RRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGS 460
Query: 143 TVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
++ L + + D G Y T N G+ S L+V
Sbjct: 461 IEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQVSCSWTLQV 504
Score = 42.7 bits (96), Expect = 0.001
Identities = 27/82 (32%), Positives = 34/82 (41%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
V EG F C ++G P P W KD I S + E+ L I +V +D
Sbjct: 1820 VVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAK 1879
Query: 167 YRITVENELGRAEASARLEVIT 188
Y N LG A +A L V T
Sbjct: 1880 YTCKAVNSLGEATCTAELIVET 1901
Score = 41.1 bits (92), Expect = 0.003
Identities = 29/100 (29%), Positives = 42/100 (42%), Gaps = 1/100 (1%)
Query: 90 PGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEE 149
P M P +P ++ V GE+V V G +W K I S + V+ E
Sbjct: 1232 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1291
Query: 150 IMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVITR 189
+ L I E G Y + VEN+LG +A L V+ +
Sbjct: 1292 GSK-LTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1330
Score = 38.3 bits (85), Expect = 0.021
Identities = 19/77 (24%), Positives = 35/77 (45%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G + +CQV+ +P I W + ++ S + + I++ ED G Y C
Sbjct: 1111 EGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKC 1170
Query: 65 EASNCLGKAKSNACLVV 81
A N G+A+ + + V
Sbjct: 1171 VAKNDAGQAECSCQVTV 1187
>AY424270-1|AAR29062.1| 1914|Homo sapiens myosin lignt chain
polypeptide kinase isoform 1 protein.
Length = 1914
Score = 95.5 bits (227), Expect = 1e-19
Identities = 55/189 (29%), Positives = 87/189 (46%), Gaps = 8/189 (4%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
DG V QV+GNP P++ W H I++ DF L I++V ED GTYTC
Sbjct: 636 DGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTC 695
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
EA N G+ ++ A L V P P F + P + G++V CA+ G+P
Sbjct: 696 EAWNSAGEVRTQAVLTV------QEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPF 749
Query: 125 PWASWDKDG-SIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
P W +DG ++ + V + E++ ++ + +V G Y I ++N +G
Sbjct: 750 PTVHWLRDGKALCKDTGHFEVLQNEDVFTLV-LKKVQPWHAGQYEILLKNRVGECSCQVS 808
Query: 184 LEVITRSGK 192
L + S +
Sbjct: 809 LMLQNSSAR 817
Score = 89.8 bits (213), Expect = 6e-18
Identities = 68/206 (33%), Positives = 95/206 (46%), Gaps = 25/206 (12%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYD-DGTARLKIKQVTAEDEGTYT 63
+G T +FE +V G P+P + W + I F GT L I V ED G YT
Sbjct: 46 EGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYT 105
Query: 64 CEASNCLGKAKSNACLVVYHT--RRLSSP------GRQMA---------------PTFYT 100
CEA+N G + L V + ++L P G + + P F T
Sbjct: 106 CEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSASAVETRPSIWGECPPKFAT 165
Query: 101 YPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVS 160
VV+EG+ F C + G P P +W K + PSAR++V EK M++LEI V+
Sbjct: 166 KLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNG-MQVLEIHGVN 224
Query: 161 IEDVGIYRITVENELGRAEASARLEV 186
+DVG+Y V N G+A SA L +
Sbjct: 225 QDDVGVYTCLVVNGSGKASMSAELSI 250
Score = 83.0 bits (196), Expect = 7e-16
Identities = 58/183 (31%), Positives = 88/183 (48%), Gaps = 10/183 (5%)
Query: 5 DGDTVEFECQVTGNPDPDIRWF-HYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYT 63
+ TV+F C+V+G P P++ WF V R E + G+ L + + D GTY+
Sbjct: 427 ENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYENAGSHYLCLLKARTRDSGTYS 486
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
C ASN G+ +C RL+ ++AP+F + + V EG++ +C+V+G P
Sbjct: 487 CTASNAQGQV---SCSWTLQVERLAV--MEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTP 541
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
P +W +G I AR T E + L I + ED G Y EN LG+ SA
Sbjct: 542 VPRITWLLNGQPI-QYARSTC---EAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAW 597
Query: 184 LEV 186
+ V
Sbjct: 598 VTV 600
Score = 79.8 bits (188), Expect = 7e-15
Identities = 60/190 (31%), Positives = 79/190 (41%), Gaps = 12/190 (6%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G +C V G P P I W + I+ S+ + G A L I+ ED GTYTC
Sbjct: 527 EGQDFVLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGTYTC 583
Query: 65 EASNCLGKAKSNACLVVYHTR--RLS------SPGRQMAPTFYTYPFNKVVEEGENVTFK 116
A N LG+ +A + V+ + R S +P + AP F + V +G VT
Sbjct: 584 LAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMT 643
Query: 117 CAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG 176
V GNP P W +G+ I S E+ L I EV ED G Y N G
Sbjct: 644 VQVSGNPPPEVIWLHNGNEIQESEDFHF-EQRGTQHSLCIQEVFPEDTGTYTCEAWNSAG 702
Query: 177 RAEASARLEV 186
A L V
Sbjct: 703 EVRTQAVLTV 712
Score = 69.3 bits (162), Expect = 1e-11
Identities = 31/78 (39%), Positives = 45/78 (57%), Gaps = 1/78 (1%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYD-DGTARLKIKQVTAEDEGTYT 63
+G F+C++ G PDP++ WF + IR+ F+ YD DG L I V +D+ YT
Sbjct: 1822 EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 1881
Query: 64 CEASNCLGKAKSNACLVV 81
C+A N LG+A A L+V
Sbjct: 1882 CKAVNSLGEATCTAELIV 1899
Score = 45.2 bits (102), Expect = 2e-04
Identities = 30/101 (29%), Positives = 41/101 (40%)
Query: 86 RLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVK 145
R+ S AP F P N ++EG F+ V+G P P +W ++G IT R +
Sbjct: 23 RVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLD 82
Query: 146 EKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
L I V ED G Y N G + + L V
Sbjct: 83 CGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
Score = 44.0 bits (99), Expect = 4e-04
Identities = 24/98 (24%), Positives = 47/98 (47%), Gaps = 1/98 (1%)
Query: 89 SPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKE 148
S + AP F + V EG+ + +C V +P W +G + + I + ++
Sbjct: 1091 SESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEG 1150
Query: 149 EIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
+ + I++ ED G+Y+ +N+ G+AE S ++ V
Sbjct: 1151 SLCSV-SIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 1187
Score = 42.7 bits (96), Expect = 0.001
Identities = 30/105 (28%), Positives = 48/105 (45%), Gaps = 4/105 (3%)
Query: 85 RRLSSPGRQMA--PTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGS-IITPSAR 141
RR+ G++ + P F + P ++ V+E + V F+C V G P P +W +G+ +
Sbjct: 401 RRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGS 460
Query: 142 ITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
I V E L + + D G Y T N G+ S L+V
Sbjct: 461 IEVYENAG-SHYLCLLKARTRDSGTYSCTASNAQGQVSCSWTLQV 504
Score = 42.7 bits (96), Expect = 0.001
Identities = 27/82 (32%), Positives = 34/82 (41%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
V EG F C ++G P P W KD I S + E+ L I +V +D
Sbjct: 1820 VVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAK 1879
Query: 167 YRITVENELGRAEASARLEVIT 188
Y N LG A +A L V T
Sbjct: 1880 YTCKAVNSLGEATCTAELIVET 1901
Score = 41.1 bits (92), Expect = 0.003
Identities = 29/100 (29%), Positives = 42/100 (42%), Gaps = 1/100 (1%)
Query: 90 PGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEE 149
P M P +P ++ V GE+V V G +W K I S + V+ E
Sbjct: 1232 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1291
Query: 150 IMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVITR 189
+ L I E G Y + VEN+LG +A L V+ +
Sbjct: 1292 GSK-LTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1330
Score = 38.3 bits (85), Expect = 0.021
Identities = 19/77 (24%), Positives = 35/77 (45%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G + +CQV+ +P I W + ++ S + + I++ ED G Y C
Sbjct: 1111 EGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKC 1170
Query: 65 EASNCLGKAKSNACLVV 81
A N G+A+ + + V
Sbjct: 1171 VAKNDAGQAECSCQVTV 1187
>AY424269-1|AAR29061.1| 1845|Homo sapiens myosin light chain
polypeptide kinase isoform 2 protein.
Length = 1845
Score = 95.5 bits (227), Expect = 1e-19
Identities = 55/189 (29%), Positives = 87/189 (46%), Gaps = 8/189 (4%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
DG V QV+GNP P++ W H I++ DF L I++V ED GTYTC
Sbjct: 567 DGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTC 626
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
EA N G+ ++ A L V P P F + P + G++V CA+ G+P
Sbjct: 627 EAWNSAGEVRTQAVLTV------QEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPF 680
Query: 125 PWASWDKDG-SIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
P W +DG ++ + V + E++ ++ + +V G Y I ++N +G
Sbjct: 681 PTVHWLRDGKALCKDTGHFEVLQNEDVFTLV-LKKVQPWHAGQYEILLKNRVGECSCQVS 739
Query: 184 LEVITRSGK 192
L + S +
Sbjct: 740 LMLQNSSAR 748
Score = 89.8 bits (213), Expect = 6e-18
Identities = 68/206 (33%), Positives = 95/206 (46%), Gaps = 25/206 (12%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYD-DGTARLKIKQVTAEDEGTYT 63
+G T +FE +V G P+P + W + I F GT L I V ED G YT
Sbjct: 46 EGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYT 105
Query: 64 CEASNCLGKAKSNACLVVYHT--RRLSSP------GRQMA---------------PTFYT 100
CEA+N G + L V + ++L P G + + P F T
Sbjct: 106 CEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSASAVETRPSIWGECPPKFAT 165
Query: 101 YPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVS 160
VV+EG+ F C + G P P +W K + PSAR++V EK M++LEI V+
Sbjct: 166 KLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNG-MQVLEIHGVN 224
Query: 161 IEDVGIYRITVENELGRAEASARLEV 186
+DVG+Y V N G+A SA L +
Sbjct: 225 QDDVGVYTCLVVNGSGKASMSAELSI 250
Score = 79.8 bits (188), Expect = 7e-15
Identities = 60/190 (31%), Positives = 79/190 (41%), Gaps = 12/190 (6%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G +C V G P P I W + I+ S+ + G A L I+ ED GTYTC
Sbjct: 458 EGQDFVLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGTYTC 514
Query: 65 EASNCLGKAKSNACLVVYHTR--RLS------SPGRQMAPTFYTYPFNKVVEEGENVTFK 116
A N LG+ +A + V+ + R S +P + AP F + V +G VT
Sbjct: 515 LAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMT 574
Query: 117 CAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG 176
V GNP P W +G+ I S E+ L I EV ED G Y N G
Sbjct: 575 VQVSGNPPPEVIWLHNGNEIQESEDFHF-EQRGTQHSLCIQEVFPEDTGTYTCEAWNSAG 633
Query: 177 RAEASARLEV 186
A L V
Sbjct: 634 EVRTQAVLTV 643
Score = 69.3 bits (162), Expect = 1e-11
Identities = 31/78 (39%), Positives = 45/78 (57%), Gaps = 1/78 (1%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYD-DGTARLKIKQVTAEDEGTYT 63
+G F+C++ G PDP++ WF + IR+ F+ YD DG L I V +D+ YT
Sbjct: 1753 EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 1812
Query: 64 CEASNCLGKAKSNACLVV 81
C+A N LG+A A L+V
Sbjct: 1813 CKAVNSLGEATCTAELIV 1830
Score = 45.2 bits (102), Expect = 2e-04
Identities = 30/101 (29%), Positives = 41/101 (40%)
Query: 86 RLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVK 145
R+ S AP F P N ++EG F+ V+G P P +W ++G IT R +
Sbjct: 23 RVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLD 82
Query: 146 EKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
L I V ED G Y N G + + L V
Sbjct: 83 CGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
Score = 44.8 bits (101), Expect = 2e-04
Identities = 31/94 (32%), Positives = 47/94 (50%), Gaps = 4/94 (4%)
Query: 93 QMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMR 152
++AP+F + + V EG++ +C+V+G P P +W +G I AR T E +
Sbjct: 442 EVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI-QYARSTC---EAGVA 497
Query: 153 ILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
L I + ED G Y EN LG+ SA + V
Sbjct: 498 ELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 531
Score = 44.0 bits (99), Expect = 4e-04
Identities = 24/98 (24%), Positives = 47/98 (47%), Gaps = 1/98 (1%)
Query: 89 SPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKE 148
S + AP F + V EG+ + +C V +P W +G + + I + ++
Sbjct: 1022 SESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEG 1081
Query: 149 EIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
+ + I++ ED G+Y+ +N+ G+AE S ++ V
Sbjct: 1082 SLCSV-SIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 1118
Score = 42.7 bits (96), Expect = 0.001
Identities = 27/82 (32%), Positives = 34/82 (41%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
V EG F C ++G P P W KD I S + E+ L I +V +D
Sbjct: 1751 VVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAK 1810
Query: 167 YRITVENELGRAEASARLEVIT 188
Y N LG A +A L V T
Sbjct: 1811 YTCKAVNSLGEATCTAELIVET 1832
Score = 41.1 bits (92), Expect = 0.003
Identities = 29/100 (29%), Positives = 42/100 (42%), Gaps = 1/100 (1%)
Query: 90 PGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEE 149
P M P +P ++ V GE+V V G +W K I S + V+ E
Sbjct: 1163 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1222
Query: 150 IMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVITR 189
+ L I E G Y + VEN+LG +A L V+ +
Sbjct: 1223 GSK-LTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1261
Score = 38.3 bits (85), Expect = 0.021
Identities = 19/77 (24%), Positives = 35/77 (45%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G + +CQV+ +P I W + ++ S + + I++ ED G Y C
Sbjct: 1042 EGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKC 1101
Query: 65 EASNCLGKAKSNACLVV 81
A N G+A+ + + V
Sbjct: 1102 VAKNDAGQAECSCQVTV 1118
>AY339601-1|AAQ02673.1| 1914|Homo sapiens long myosin light chain
kinase protein.
Length = 1914
Score = 95.5 bits (227), Expect = 1e-19
Identities = 55/189 (29%), Positives = 87/189 (46%), Gaps = 8/189 (4%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
DG V QV+GNP P++ W H I++ DF L I++V ED GTYTC
Sbjct: 636 DGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTC 695
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
EA N G+ ++ A L V P P F + P + G++V CA+ G+P
Sbjct: 696 EAWNSAGEVRTQAVLTV------QEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPF 749
Query: 125 PWASWDKDG-SIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
P W +DG ++ + V + E++ ++ + +V G Y I ++N +G
Sbjct: 750 PTVHWLRDGKALCKDTGHFEVLQNEDVFTLV-LKKVQPWHAGQYEILLKNRVGECSCQVS 808
Query: 184 LEVITRSGK 192
L + S +
Sbjct: 809 LMLQNSSAR 817
Score = 89.8 bits (213), Expect = 6e-18
Identities = 68/206 (33%), Positives = 95/206 (46%), Gaps = 25/206 (12%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYD-DGTARLKIKQVTAEDEGTYT 63
+G T +FE +V G P+P + W + I F GT L I V ED G YT
Sbjct: 46 EGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYT 105
Query: 64 CEASNCLGKAKSNACLVVYHT--RRLSSP------GRQMA---------------PTFYT 100
CEA+N G + L V + ++L P G + + P F T
Sbjct: 106 CEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSASAVETRPSIWGECPPKFAT 165
Query: 101 YPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVS 160
VV+EG+ F C + G P P +W K + PSAR++V EK M++LEI V+
Sbjct: 166 KLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNG-MQVLEIHGVN 224
Query: 161 IEDVGIYRITVENELGRAEASARLEV 186
+DVG+Y V N G+A SA L +
Sbjct: 225 QDDVGVYTCLVVNGSGKASMSAELSI 250
Score = 85.0 bits (201), Expect = 2e-16
Identities = 59/183 (32%), Positives = 88/183 (48%), Gaps = 10/183 (5%)
Query: 5 DGDTVEFECQVTGNPDPDIRWF-HYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYT 63
+ TV+F C+V+G P P++ WF V R E D G+ L + + D GTY+
Sbjct: 427 ENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYS 486
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
C ASN G+ +C RL+ ++AP+F + + V EG++ +C+V+G P
Sbjct: 487 CTASNAQGQV---SCSWTLQVERLAV--MEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTP 541
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
P +W +G I AR T E + L I + ED G Y EN LG+ SA
Sbjct: 542 VPRITWLLNGQPI-QYARSTC---EAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAW 597
Query: 184 LEV 186
+ V
Sbjct: 598 VTV 600
Score = 79.8 bits (188), Expect = 7e-15
Identities = 60/190 (31%), Positives = 79/190 (41%), Gaps = 12/190 (6%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G +C V G P P I W + I+ S+ + G A L I+ ED GTYTC
Sbjct: 527 EGQDFVLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGTYTC 583
Query: 65 EASNCLGKAKSNACLVVYHTR--RLS------SPGRQMAPTFYTYPFNKVVEEGENVTFK 116
A N LG+ +A + V+ + R S +P + AP F + V +G VT
Sbjct: 584 LAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMT 643
Query: 117 CAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG 176
V GNP P W +G+ I S E+ L I EV ED G Y N G
Sbjct: 644 VQVSGNPPPEVIWLHNGNEIQESEDFHF-EQRGTQHSLCIQEVFPEDTGTYTCEAWNSAG 702
Query: 177 RAEASARLEV 186
A L V
Sbjct: 703 EVRTQAVLTV 712
Score = 69.3 bits (162), Expect = 1e-11
Identities = 31/78 (39%), Positives = 45/78 (57%), Gaps = 1/78 (1%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYD-DGTARLKIKQVTAEDEGTYT 63
+G F+C++ G PDP++ WF + IR+ F+ YD DG L I V +D+ YT
Sbjct: 1822 EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 1881
Query: 64 CEASNCLGKAKSNACLVV 81
C+A N LG+A A L+V
Sbjct: 1882 CKAVNSLGEATCTAELIV 1899
Score = 45.2 bits (102), Expect = 2e-04
Identities = 30/101 (29%), Positives = 41/101 (40%)
Query: 86 RLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVK 145
R+ S AP F P N ++EG F+ V+G P P +W ++G IT R +
Sbjct: 23 RVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLD 82
Query: 146 EKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
L I V ED G Y N G + + L V
Sbjct: 83 CGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
Score = 44.0 bits (99), Expect = 4e-04
Identities = 24/98 (24%), Positives = 47/98 (47%), Gaps = 1/98 (1%)
Query: 89 SPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKE 148
S + AP F + V EG+ + +C V +P W +G + + I + ++
Sbjct: 1091 SESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEG 1150
Query: 149 EIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
+ + I++ ED G+Y+ +N+ G+AE S ++ V
Sbjct: 1151 SLCSV-SIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 1187
Score = 43.2 bits (97), Expect = 7e-04
Identities = 27/104 (25%), Positives = 47/104 (45%), Gaps = 2/104 (1%)
Query: 85 RRLSSPGRQMA--PTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARI 142
RR+ G++ + P F + P ++ V+E + V F+C V G P P +W +G+ +
Sbjct: 401 RRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGS 460
Query: 143 TVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
++ L + + D G Y T N G+ S L+V
Sbjct: 461 IEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQVSCSWTLQV 504
Score = 42.7 bits (96), Expect = 0.001
Identities = 27/82 (32%), Positives = 34/82 (41%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
V EG F C ++G P P W KD I S + E+ L I +V +D
Sbjct: 1820 VVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAK 1879
Query: 167 YRITVENELGRAEASARLEVIT 188
Y N LG A +A L V T
Sbjct: 1880 YTCKAVNSLGEATCTAELIVET 1901
Score = 41.1 bits (92), Expect = 0.003
Identities = 29/100 (29%), Positives = 42/100 (42%), Gaps = 1/100 (1%)
Query: 90 PGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEE 149
P M P +P ++ V GE+V V G +W K I S + V+ E
Sbjct: 1232 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1291
Query: 150 IMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVITR 189
+ L I E G Y + VEN+LG +A L V+ +
Sbjct: 1292 GSK-LTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1330
Score = 38.3 bits (85), Expect = 0.021
Identities = 19/77 (24%), Positives = 35/77 (45%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G + +CQV+ +P I W + ++ S + + I++ ED G Y C
Sbjct: 1111 EGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKC 1170
Query: 65 EASNCLGKAKSNACLVV 81
A N G+A+ + + V
Sbjct: 1171 VAKNDAGQAECSCQVTV 1187
>AF069603-1|AAD15923.1| 1793|Homo sapiens myosin light chain kinase
isoform 3B protein.
Length = 1793
Score = 95.5 bits (227), Expect = 1e-19
Identities = 55/189 (29%), Positives = 87/189 (46%), Gaps = 8/189 (4%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
DG V QV+GNP P++ W H I++ DF L I++V ED GTYTC
Sbjct: 567 DGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLWIQEVFPEDTGTYTC 626
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
EA N G+ ++ A L V P P F + P + G++V CA+ G+P
Sbjct: 627 EAWNSAGEVRTQAVLTV------QEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPF 680
Query: 125 PWASWDKDG-SIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
P W +DG ++ + V + E++ ++ + +V G Y I ++N +G
Sbjct: 681 PTVHWLRDGKALCKDTGHFEVLQNEDVFTLV-LKKVQPWHAGQYEILLKNRVGECSCQVS 739
Query: 184 LEVITRSGK 192
L + S +
Sbjct: 740 LMLQNSSAR 748
Score = 89.8 bits (213), Expect = 6e-18
Identities = 68/206 (33%), Positives = 95/206 (46%), Gaps = 25/206 (12%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYD-DGTARLKIKQVTAEDEGTYT 63
+G T +FE +V G P+P + W + I F GT L I V ED G YT
Sbjct: 46 EGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYT 105
Query: 64 CEASNCLGKAKSNACLVVYHT--RRLSSP------GRQMA---------------PTFYT 100
CEA+N G + L V + ++L P G + + P F T
Sbjct: 106 CEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSASAVETRPSIWGECPPKFAT 165
Query: 101 YPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVS 160
VV+EG+ F C + G P P +W K + PSAR++V EK M++LEI V+
Sbjct: 166 KLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNG-MQVLEIHGVN 224
Query: 161 IEDVGIYRITVENELGRAEASARLEV 186
+DVG+Y V N G+A SA L +
Sbjct: 225 QDDVGVYTCLVVNGSGKASMSAELSI 250
Score = 80.2 bits (189), Expect = 5e-15
Identities = 60/190 (31%), Positives = 79/190 (41%), Gaps = 12/190 (6%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G +C V G P P I W + I+ S+ + G A L I+ ED GTYTC
Sbjct: 458 EGQDFVLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGTYTC 514
Query: 65 EASNCLGKAKSNACLVVYHTR--RLS------SPGRQMAPTFYTYPFNKVVEEGENVTFK 116
A N LG+ +A + V+ + R S +P + AP F + V +G VT
Sbjct: 515 LAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMT 574
Query: 117 CAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG 176
V GNP P W +G+ I S E+ L I EV ED G Y N G
Sbjct: 575 VQVSGNPPPEVIWLHNGNEIQESEDFHF-EQRGTQHSLWIQEVFPEDTGTYTCEAWNSAG 633
Query: 177 RAEASARLEV 186
A L V
Sbjct: 634 EVRTQAVLTV 643
Score = 66.5 bits (155), Expect = 7e-11
Identities = 29/74 (39%), Positives = 42/74 (56%), Gaps = 1/74 (1%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYD-DGTARLKIKQVTAEDEGTYT 63
+G F+C++ G PDP++ WF + IR+ F+ YD DG L I V +D+ YT
Sbjct: 1701 EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 1760
Query: 64 CEASNCLGKAKSNA 77
C+A N LG+A A
Sbjct: 1761 CKAVNSLGEATCTA 1774
Score = 46.0 bits (104), Expect = 1e-04
Identities = 24/98 (24%), Positives = 48/98 (48%), Gaps = 1/98 (1%)
Query: 89 SPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKE 148
S + AP F + V EG+ + +C V +P W +G + + I + ++
Sbjct: 1022 SESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEG 1081
Query: 149 EIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
+ + I++ +ED G+Y+ +N+ G+AE S ++ V
Sbjct: 1082 SLCSV-SIEKALLEDRGLYKCVAKNDAGQAECSCQVTV 1118
Score = 45.2 bits (102), Expect = 2e-04
Identities = 30/101 (29%), Positives = 41/101 (40%)
Query: 86 RLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVK 145
R+ S AP F P N ++EG F+ V+G P P +W ++G IT R +
Sbjct: 23 RVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLD 82
Query: 146 EKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
L I V ED G Y N G + + L V
Sbjct: 83 CGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
Score = 44.8 bits (101), Expect = 2e-04
Identities = 31/94 (32%), Positives = 47/94 (50%), Gaps = 4/94 (4%)
Query: 93 QMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMR 152
++AP+F + + V EG++ +C+V+G P P +W +G I AR T E +
Sbjct: 442 EVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI-QYARSTC---EAGVA 497
Query: 153 ILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
L I + ED G Y EN LG+ SA + V
Sbjct: 498 ELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 531
Score = 42.3 bits (95), Expect = 0.001
Identities = 30/100 (30%), Positives = 42/100 (42%), Gaps = 1/100 (1%)
Query: 90 PGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEE 149
P M P +P ++ V GE+V V G +W K I S I V+ E
Sbjct: 1163 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQDSEHIKVENSEN 1222
Query: 150 IMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVITR 189
+ L I E G Y + VEN+LG +A L V+ +
Sbjct: 1223 GSK-LTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1261
Score = 39.9 bits (89), Expect = 0.007
Identities = 24/76 (31%), Positives = 31/76 (40%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
V EG F C ++G P P W KD I S + E+ L I +V +D
Sbjct: 1699 VVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAK 1758
Query: 167 YRITVENELGRAEASA 182
Y N LG A +A
Sbjct: 1759 YTCKAVNSLGEATCTA 1774
Score = 38.3 bits (85), Expect = 0.021
Identities = 19/77 (24%), Positives = 35/77 (45%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G + +CQV+ +P I W + ++ S + + I++ ED G Y C
Sbjct: 1042 EGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALLEDRGLYKC 1101
Query: 65 EASNCLGKAKSNACLVV 81
A N G+A+ + + V
Sbjct: 1102 VAKNDAGQAECSCQVTV 1118
Score = 33.5 bits (73), Expect = 0.59
Identities = 20/76 (26%), Positives = 32/76 (42%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G++VE +VTG W + + I+D + + ++L I E G YT
Sbjct: 1183 GESVELFGKVTGTQPITCTWMKFRKQIQDSEHIKVENSENGSKLTILAARQEHCGCYTLL 1242
Query: 66 ASNCLGKAKSNACLVV 81
N LG ++ L V
Sbjct: 1243 VENKLGSRQAQVNLTV 1258
>AF069602-1|AAD15922.1| 1862|Homo sapiens myosin light chain kinase
isoform 3A protein.
Length = 1862
Score = 95.5 bits (227), Expect = 1e-19
Identities = 55/189 (29%), Positives = 87/189 (46%), Gaps = 8/189 (4%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
DG V QV+GNP P++ W H I++ DF L I++V ED GTYTC
Sbjct: 636 DGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLWIQEVFPEDTGTYTC 695
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
EA N G+ ++ A L V P P F + P + G++V CA+ G+P
Sbjct: 696 EAWNSAGEVRTQAVLTV------QEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPF 749
Query: 125 PWASWDKDG-SIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
P W +DG ++ + V + E++ ++ + +V G Y I ++N +G
Sbjct: 750 PTVHWLRDGKALCKDTGHFEVLQNEDVFTLV-LKKVQPWHAGQYEILLKNRVGECSCQVS 808
Query: 184 LEVITRSGK 192
L + S +
Sbjct: 809 LMLQNSSAR 817
Score = 89.8 bits (213), Expect = 6e-18
Identities = 68/206 (33%), Positives = 95/206 (46%), Gaps = 25/206 (12%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYD-DGTARLKIKQVTAEDEGTYT 63
+G T +FE +V G P+P + W + I F GT L I V ED G YT
Sbjct: 46 EGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYT 105
Query: 64 CEASNCLGKAKSNACLVVYHT--RRLSSP------GRQMA---------------PTFYT 100
CEA+N G + L V + ++L P G + + P F T
Sbjct: 106 CEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSASAVETRPSIWGECPPKFAT 165
Query: 101 YPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVS 160
VV+EG+ F C + G P P +W K + PSAR++V EK M++LEI V+
Sbjct: 166 KLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNG-MQVLEIHGVN 224
Query: 161 IEDVGIYRITVENELGRAEASARLEV 186
+DVG+Y V N G+A SA L +
Sbjct: 225 QDDVGVYTCLVVNGSGKASMSAELSI 250
Score = 85.0 bits (201), Expect = 2e-16
Identities = 59/183 (32%), Positives = 88/183 (48%), Gaps = 10/183 (5%)
Query: 5 DGDTVEFECQVTGNPDPDIRWF-HYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYT 63
+ TV+F C+V+G P P++ WF V R E D G+ L + + D GTY+
Sbjct: 427 ENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYS 486
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
C ASN G+ +C RL+ ++AP+F + + V EG++ +C+V+G P
Sbjct: 487 CTASNAQGQV---SCSWTLQVERLAV--MEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTP 541
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
P +W +G I AR T E + L I + ED G Y EN LG+ SA
Sbjct: 542 VPRITWLLNGQPI-QYARSTC---EAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAW 597
Query: 184 LEV 186
+ V
Sbjct: 598 VTV 600
Score = 80.2 bits (189), Expect = 5e-15
Identities = 60/190 (31%), Positives = 79/190 (41%), Gaps = 12/190 (6%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G +C V G P P I W + I+ S+ + G A L I+ ED GTYTC
Sbjct: 527 EGQDFVLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGTYTC 583
Query: 65 EASNCLGKAKSNACLVVYHTR--RLS------SPGRQMAPTFYTYPFNKVVEEGENVTFK 116
A N LG+ +A + V+ + R S +P + AP F + V +G VT
Sbjct: 584 LAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMT 643
Query: 117 CAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG 176
V GNP P W +G+ I S E+ L I EV ED G Y N G
Sbjct: 644 VQVSGNPPPEVIWLHNGNEIQESEDFHF-EQRGTQHSLWIQEVFPEDTGTYTCEAWNSAG 702
Query: 177 RAEASARLEV 186
A L V
Sbjct: 703 EVRTQAVLTV 712
Score = 66.5 bits (155), Expect = 7e-11
Identities = 29/74 (39%), Positives = 42/74 (56%), Gaps = 1/74 (1%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYD-DGTARLKIKQVTAEDEGTYT 63
+G F+C++ G PDP++ WF + IR+ F+ YD DG L I V +D+ YT
Sbjct: 1770 EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 1829
Query: 64 CEASNCLGKAKSNA 77
C+A N LG+A A
Sbjct: 1830 CKAVNSLGEATCTA 1843
Score = 46.0 bits (104), Expect = 1e-04
Identities = 24/98 (24%), Positives = 48/98 (48%), Gaps = 1/98 (1%)
Query: 89 SPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKE 148
S + AP F + V EG+ + +C V +P W +G + + I + ++
Sbjct: 1091 SESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEG 1150
Query: 149 EIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
+ + I++ +ED G+Y+ +N+ G+AE S ++ V
Sbjct: 1151 SLCSV-SIEKALLEDRGLYKCVAKNDAGQAECSCQVTV 1187
Score = 45.2 bits (102), Expect = 2e-04
Identities = 30/101 (29%), Positives = 41/101 (40%)
Query: 86 RLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVK 145
R+ S AP F P N ++EG F+ V+G P P +W ++G IT R +
Sbjct: 23 RVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLD 82
Query: 146 EKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
L I V ED G Y N G + + L V
Sbjct: 83 CGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
Score = 43.2 bits (97), Expect = 7e-04
Identities = 27/104 (25%), Positives = 47/104 (45%), Gaps = 2/104 (1%)
Query: 85 RRLSSPGRQMA--PTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARI 142
RR+ G++ + P F + P ++ V+E + V F+C V G P P +W +G+ +
Sbjct: 401 RRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGS 460
Query: 143 TVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
++ L + + D G Y T N G+ S L+V
Sbjct: 461 IEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQVSCSWTLQV 504
Score = 42.3 bits (95), Expect = 0.001
Identities = 30/100 (30%), Positives = 42/100 (42%), Gaps = 1/100 (1%)
Query: 90 PGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEE 149
P M P +P ++ V GE+V V G +W K I S I V+ E
Sbjct: 1232 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQDSEHIKVENSEN 1291
Query: 150 IMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVITR 189
+ L I E G Y + VEN+LG +A L V+ +
Sbjct: 1292 GSK-LTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1330
Score = 39.9 bits (89), Expect = 0.007
Identities = 24/76 (31%), Positives = 31/76 (40%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
V EG F C ++G P P W KD I S + E+ L I +V +D
Sbjct: 1768 VVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAK 1827
Query: 167 YRITVENELGRAEASA 182
Y N LG A +A
Sbjct: 1828 YTCKAVNSLGEATCTA 1843
Score = 38.3 bits (85), Expect = 0.021
Identities = 19/77 (24%), Positives = 35/77 (45%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G + +CQV+ +P I W + ++ S + + I++ ED G Y C
Sbjct: 1111 EGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALLEDRGLYKC 1170
Query: 65 EASNCLGKAKSNACLVV 81
A N G+A+ + + V
Sbjct: 1171 VAKNDAGQAECSCQVTV 1187
Score = 33.5 bits (73), Expect = 0.59
Identities = 20/76 (26%), Positives = 32/76 (42%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G++VE +VTG W + + I+D + + ++L I E G YT
Sbjct: 1252 GESVELFGKVTGTQPITCTWMKFRKQIQDSEHIKVENSENGSKLTILAARQEHCGCYTLL 1311
Query: 66 ASNCLGKAKSNACLVV 81
N LG ++ L V
Sbjct: 1312 VENKLGSRQAQVNLTV 1327
>AF069601-1|AAD15921.2| 1845|Homo sapiens myosin light chain kinase
isoform 2 protein.
Length = 1845
Score = 95.5 bits (227), Expect = 1e-19
Identities = 55/189 (29%), Positives = 87/189 (46%), Gaps = 8/189 (4%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
DG V QV+GNP P++ W H I++ DF L I++V ED GTYTC
Sbjct: 567 DGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLWIQEVFPEDTGTYTC 626
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
EA N G+ ++ A L V P P F + P + G++V CA+ G+P
Sbjct: 627 EAWNSAGEVRTQAVLTV------QEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPF 680
Query: 125 PWASWDKDG-SIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
P W +DG ++ + V + E++ ++ + +V G Y I ++N +G
Sbjct: 681 PTVHWLRDGKALCKDTGHFEVLQNEDVFTLV-LKKVQPWHAGQYEILLKNRVGECSCQVS 739
Query: 184 LEVITRSGK 192
L + S +
Sbjct: 740 LMLQNSSAR 748
Score = 89.8 bits (213), Expect = 6e-18
Identities = 68/206 (33%), Positives = 95/206 (46%), Gaps = 25/206 (12%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYD-DGTARLKIKQVTAEDEGTYT 63
+G T +FE +V G P+P + W + I F GT L I V ED G YT
Sbjct: 46 EGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYT 105
Query: 64 CEASNCLGKAKSNACLVVYHT--RRLSSP------GRQMA---------------PTFYT 100
CEA+N G + L V + ++L P G + + P F T
Sbjct: 106 CEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSASAVETRPSIWGECPPKFAT 165
Query: 101 YPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVS 160
VV+EG+ F C + G P P +W K + PSAR++V EK M++LEI V+
Sbjct: 166 KLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNG-MQVLEIHGVN 224
Query: 161 IEDVGIYRITVENELGRAEASARLEV 186
+DVG+Y V N G+A SA L +
Sbjct: 225 QDDVGVYTCLVVNGSGKASMSAELSI 250
Score = 80.2 bits (189), Expect = 5e-15
Identities = 60/190 (31%), Positives = 79/190 (41%), Gaps = 12/190 (6%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G +C V G P P I W + I+ S+ + G A L I+ ED GTYTC
Sbjct: 458 EGQDFVLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGTYTC 514
Query: 65 EASNCLGKAKSNACLVVYHTR--RLS------SPGRQMAPTFYTYPFNKVVEEGENVTFK 116
A N LG+ +A + V+ + R S +P + AP F + V +G VT
Sbjct: 515 LAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMT 574
Query: 117 CAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG 176
V GNP P W +G+ I S E+ L I EV ED G Y N G
Sbjct: 575 VQVSGNPPPEVIWLHNGNEIQESEDFHF-EQRGTQHSLWIQEVFPEDTGTYTCEAWNSAG 633
Query: 177 RAEASARLEV 186
A L V
Sbjct: 634 EVRTQAVLTV 643
Score = 69.3 bits (162), Expect = 1e-11
Identities = 31/78 (39%), Positives = 45/78 (57%), Gaps = 1/78 (1%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYD-DGTARLKIKQVTAEDEGTYT 63
+G F+C++ G PDP++ WF + IR+ F+ YD DG L I V +D+ YT
Sbjct: 1753 EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 1812
Query: 64 CEASNCLGKAKSNACLVV 81
C+A N LG+A A L+V
Sbjct: 1813 CKAVNSLGEATCTAELIV 1830
Score = 45.2 bits (102), Expect = 2e-04
Identities = 30/101 (29%), Positives = 41/101 (40%)
Query: 86 RLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVK 145
R+ S AP F P N ++EG F+ V+G P P +W ++G IT R +
Sbjct: 23 RVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLD 82
Query: 146 EKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
L I V ED G Y N G + + L V
Sbjct: 83 CGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
Score = 44.8 bits (101), Expect = 2e-04
Identities = 31/94 (32%), Positives = 47/94 (50%), Gaps = 4/94 (4%)
Query: 93 QMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMR 152
++AP+F + + V EG++ +C+V+G P P +W +G I AR T E +
Sbjct: 442 EVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI-QYARSTC---EAGVA 497
Query: 153 ILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
L I + ED G Y EN LG+ SA + V
Sbjct: 498 ELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 531
Score = 44.0 bits (99), Expect = 4e-04
Identities = 24/98 (24%), Positives = 47/98 (47%), Gaps = 1/98 (1%)
Query: 89 SPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKE 148
S + AP F + V EG+ + +C V +P W +G + + I + ++
Sbjct: 1022 SESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEG 1081
Query: 149 EIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
+ + I++ ED G+Y+ +N+ G+AE S ++ V
Sbjct: 1082 SLCSV-SIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 1118
Score = 42.7 bits (96), Expect = 0.001
Identities = 27/82 (32%), Positives = 34/82 (41%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
V EG F C ++G P P W KD I S + E+ L I +V +D
Sbjct: 1751 VVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAK 1810
Query: 167 YRITVENELGRAEASARLEVIT 188
Y N LG A +A L V T
Sbjct: 1811 YTCKAVNSLGEATCTAELIVET 1832
Score = 41.1 bits (92), Expect = 0.003
Identities = 29/100 (29%), Positives = 42/100 (42%), Gaps = 1/100 (1%)
Query: 90 PGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEE 149
P M P +P ++ V GE+V V G +W K I S + V+ E
Sbjct: 1163 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1222
Query: 150 IMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVITR 189
+ L I E G Y + VEN+LG +A L V+ +
Sbjct: 1223 GSK-LTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1261
Score = 38.3 bits (85), Expect = 0.021
Identities = 19/77 (24%), Positives = 35/77 (45%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G + +CQV+ +P I W + ++ S + + I++ ED G Y C
Sbjct: 1042 EGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKC 1101
Query: 65 EASNCLGKAKSNACLVV 81
A N G+A+ + + V
Sbjct: 1102 VAKNDAGQAECSCQVTV 1118
>X90569-1|CAA62189.1| 7962|Homo sapiens elastic titin protein.
Length = 7962
Score = 93.9 bits (223), Expect = 4e-19
Identities = 64/203 (31%), Positives = 87/203 (42%), Gaps = 13/203 (6%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G +V EC+V G+P + WFH I ++++ D T L + + D G YTC
Sbjct: 4361 GSSVVMECKVYGSPPISVSWFHEGNEISSGRKYQTTLTDNTCALTVNMLEESDSGDYTCI 4420
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A+N G + +A L V + P+F P V G NVTF VKG P
Sbjct: 4421 ATNMAGSDECSAPLTV-----------REPPSFVQKPDPMDVLTGTNVTFTSIVKGTPPF 4469
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
SW K S + P R V ++ + LE+ +V G Y V NE G+A + L
Sbjct: 4470 SVSWFKGSSELVPGDRCNVSLEDSVAE-LELFDVDTSQSGEYTCIVSNEAGKASCTTHL- 4527
Query: 186 VITRSGKFYGGLRAYSASPRKCL 208
I KF L YS K L
Sbjct: 4528 YIKAPAKFVKRLNDYSIEKGKPL 4550
Score = 81.8 bits (193), Expect = 2e-15
Identities = 53/203 (26%), Positives = 86/203 (42%), Gaps = 13/203 (6%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G + EC+V G+ + WFH I A +++++ D L++ + + D G YTC
Sbjct: 2479 GASCILECKVAGSSPISVAWFHEKTKIVSGAKYQTTFSDNVCTLQLNSLDSSDMGNYTCV 2538
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A+N G + A L V Q P+F P V G+NVTF ++G P
Sbjct: 2539 AANVAGSDECRAVLTV-----------QEPPSFVKEPEPLEVLPGKNVTFTSVIRGTPPF 2587
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
+W + + R + ++ + LE+ + I G Y V N G+A + RL
Sbjct: 2588 KVNWFRGARELVKGDRCNIYFEDTVAE-LELFNIDISQSGEYTCVVSNNAGQASCTTRL- 2645
Query: 186 VITRSGKFYGGLRAYSASPRKCL 208
+ F L +S P K +
Sbjct: 2646 FVKEPAAFLKRLSDHSVEPGKSI 2668
Score = 81.4 bits (192), Expect = 2e-15
Identities = 51/180 (28%), Positives = 82/180 (45%), Gaps = 11/180 (6%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+ +C+V G P+ I W+ +R ++ + + A L I +V D G Y+C+
Sbjct: 3699 GEPATLQCKVDGTPEIRISWYKEHTKLRSAPAYKMQFKNNVASLVINKVDHSDVGEYSCK 3758
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEE-GENVTFKCAVKGNPS 124
A N +G S+A LV+ R+L P F+ V E G V F+C + G+
Sbjct: 3759 ADNSVGAVASSAVLVI-KARKL--------PPFFARKLKDVHETLGFPVAFECRINGSEP 3809
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
SW KDG ++ A + + L+I + +G Y + N LG A +SA+L
Sbjct: 3810 LQVSWYKDGVLLKDDANLQTSFVHNV-ATLQILQTDQSHIGQYNCSASNPLGTASSSAKL 3868
Score = 81.4 bits (192), Expect = 2e-15
Identities = 54/183 (29%), Positives = 86/183 (46%), Gaps = 13/183 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G V FEC++ G+ + W+ +++D A+ ++S+ A L+I Q G Y C
Sbjct: 3795 GFPVAFECRINGSEPLQVSWYKDGVLLKDDANLQTSFVHNVATLQILQTDQSHIGQYNCS 3854
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
ASN LG A S+A L++ ++ P F P + + GE+ TFKC V G
Sbjct: 3855 ASNPLGTASSSAKLILSE--------HEVPPFFDLKPVSVDLALGESGTFKCHVTGTAPI 3906
Query: 126 WASWDKDGSIITPSA--RITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
+W KD I P ++T+ E + +L++ + D G Y N G+ SA+
Sbjct: 3907 KITWAKDNREIRPGGNYKMTLVENTATLTVLKVGK---GDAGQYTCYASNIAGKDSCSAQ 3963
Query: 184 LEV 186
L V
Sbjct: 3964 LGV 3966
Score = 80.2 bits (189), Expect = 5e-15
Identities = 55/181 (30%), Positives = 82/181 (45%), Gaps = 9/181 (4%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G V C++ G+ + W+ ++RD + ++S+ D A LKI Q G Y+C
Sbjct: 2854 GLPVTLTCRLNGSAPIQVCWYRDGVLLRDHENLQTSFVDNVATLKILQTDLSHSGQYSCS 2913
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
ASN LG A S+A RL++ + +P F P + V GE+ F+C V G
Sbjct: 2914 ASNPLGTASSSA--------RLTAREPKKSPFFDIKPVSIDVIAGESADFECHVTGAQPM 2965
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
+W KD I P T+ L I +V D G Y N++G+ SA+L
Sbjct: 2966 RITWSKDNKEIRPGGNYTITCVGNTPH-LRILKVGKGDSGQYTCQATNDVGKDMCSAQLS 3024
Query: 186 V 186
V
Sbjct: 3025 V 3025
Score = 80.2 bits (189), Expect = 5e-15
Identities = 52/183 (28%), Positives = 91/183 (49%), Gaps = 12/183 (6%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G++ +FEC VTG + W + IR ++ SY + +A L + +V D G YTC
Sbjct: 4832 GESADFECHVTGTQPIKVSWAKDSREIRSGGKYQISYLENSAHLTVLKVDKGDSGQYTCY 4891
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKC--AVKGNP 123
A N +GK ++C T +L+ R + P+F T ++ VEE E +FK V G+
Sbjct: 4892 AVNEVGK---DSC-----TAQLNIKERLIPPSF-TKRLSETVEETEGNSFKLEGRVAGSQ 4942
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
+W K+ I P++ + K + +L++ + + D G+Y V N+ G A ++
Sbjct: 4943 PITVAWYKNNIEIQPTSNCEITFKNNTL-VLQVRKAGMNDAGLYTCKVSNDAGSALCTSS 5001
Query: 184 LEV 186
+ +
Sbjct: 5002 IVI 5004
Score = 79.8 bits (188), Expect = 7e-15
Identities = 52/181 (28%), Positives = 87/181 (48%), Gaps = 11/181 (6%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G++ F+C VTG I W IR +++ + + TA L + +V D G YTC
Sbjct: 3891 GESGTFKCHVTGTAPIKITWAKDNREIRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCY 3950
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
ASN GK +A L V R +++ P +++V++ E ++C + G+P
Sbjct: 3951 ASNIAGKDSCSAQLGVQEPPRFI---KKLEP-------SRIVKQDEFTRYECKIGGSPEI 4000
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
W KD + I S++ + + + +LE+ +S+ED G Y N G A +S L+
Sbjct: 4001 KVLWYKDETEIQESSKFRMSFVDSV-AVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLK 4059
Query: 186 V 186
V
Sbjct: 4060 V 4060
Score = 79.4 bits (187), Expect = 9e-15
Identities = 47/179 (26%), Positives = 78/179 (43%), Gaps = 9/179 (5%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
GD+V +CQV G P+ + W+ +R ++ + + + A L +V D G YTC+
Sbjct: 2758 GDSVSLQCQVAGTPEITVSWYKGDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGEYTCK 2817
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A N +G A S + RQ+ P+F + G VT C + G+
Sbjct: 2818 AENSIGTASSKTVFRIQE--------RQLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPI 2869
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
W +DG ++ + + + L+I + + G Y + N LG A +SARL
Sbjct: 2870 QVCWYRDGVLLRDHENLQTSFVDNV-ATLKILQTDLSHSGQYSCSASNPLGTASSSARL 2927
Score = 78.2 bits (184), Expect = 2e-14
Identities = 47/180 (26%), Positives = 78/180 (43%), Gaps = 12/180 (6%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G++++ EC+++G+P+ + WF + + + S+ + A L I + +AED G Y CE
Sbjct: 3044 GESIQLECKISGSPEIKVSWFRNDSELHESWKYNMSFINSVALLTINEASAEDSGDYICE 3103
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A N +G A + L V + P F P +G +V +C + G P
Sbjct: 3104 AHNGVGDASCSTALTV-----------KAPPVFTQKPSPVGALKGSDVILQCEISGTPPF 3152
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
W KD + S + + K L I + DVG Y NE+G S ++
Sbjct: 3153 EVVWVKDRKQVRNSKKFKITSK-HFDTNLHILNLEASDVGEYHCKATNEVGSDTCSCSVK 3211
Score = 78.2 bits (184), Expect = 2e-14
Identities = 50/181 (27%), Positives = 81/181 (44%), Gaps = 13/181 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
GD+ +CQ+ G P+ + W+ +R ++ + + A L QV D G Y C+
Sbjct: 4640 GDSASLQCQLAGTPEIGVSWYKGDTKLRPTTTYKMHFRNNVATLVFNQVDINDSGEYICK 4699
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A N +G+ ++ L V + S RQ+ T G V F CA+ G+
Sbjct: 4700 AENSVGEVSASTFLTVQEQKLPPSFSRQLRDVQETV--------GLPVVFDCAISGSEPI 4751
Query: 126 WASWDKDGSII--TPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
SW KDG + +P+ + + + + I + D S+ G Y T N +G A +SAR
Sbjct: 4752 SVSWYKDGKPLKDSPNVQTSFLDNTATLNIFKTDR-SL--AGQYSCTATNPIGSASSSAR 4808
Query: 184 L 184
L
Sbjct: 4809 L 4809
Score = 77.8 bits (183), Expect = 3e-14
Identities = 50/184 (27%), Positives = 76/184 (41%), Gaps = 10/184 (5%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G +F C++ P+ +WF I + + L+I + D G YTC+
Sbjct: 135 GHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCK 194
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
ASN G A L V PTF + P + G+ F C V G P
Sbjct: 195 ASNEYGSVSCTATLTVTEA---------YPPTFLSRPKSLTTFVGKAAKFICTVTGTPVI 245
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
W KDG+ ++PS + + E ILE+ ++I+D G+Y N+ G A L
Sbjct: 246 ETIWQKDGAALSPSPNWRISDAEN-KHILELSNLTIQDRGVYSCKASNKFGADICQAELI 304
Query: 186 VITR 189
+I +
Sbjct: 305 IIDK 308
Score = 77.4 bits (182), Expect = 4e-14
Identities = 61/205 (29%), Positives = 91/205 (44%), Gaps = 14/205 (6%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G+ V+ C V G+ I+W I+ S+ GTA L+++ V D G Y C
Sbjct: 5024 EGEYVQLSCHVQGSEPIRIQWLKAGREIKPSDRCSFSFASGTAVLELRDVAKADSGDYVC 5083
Query: 65 EASNCLGK--AKSNACL-----VVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKC 117
+ASN G KS + V T++ + GR F + P + V E TF
Sbjct: 5084 KASNVAGSDTTKSKVTIKDKPAVAPATKKAAVDGRLF---FVSEPQSIRVVEKTTATFIA 5140
Query: 118 AVKGNPSPWASWDK-DGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG 176
V G+P P W K + R+ + +K + + LEI + + D G+YR NE G
Sbjct: 5141 KVGGDPIPNVKWTKGKWRQLNQGGRVFIHQKGDEAK-LEIRDTTKTDSGLYRCVAFNEHG 5199
Query: 177 RAEASARLEVITR--SGKFYGGLRA 199
E++ L+V R K G LRA
Sbjct: 5200 EIESNVNLQVDERKKQEKIEGDLRA 5224
Score = 77.0 bits (181), Expect = 5e-14
Identities = 45/166 (27%), Positives = 77/166 (46%), Gaps = 12/166 (7%)
Query: 11 FECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCL 70
+EC++ G+P+ + W+ I++ + F S+ D A L++ ++ ED G YTCEA N
Sbjct: 3990 YECKIGGSPEIKVLWYKDETEIQESSKFRMSFVDSVAVLEMHNLSVEDSGDYTCEAHNAA 4049
Query: 71 GKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWD 130
G A S+ L ++ P P F P +G +V +C ++G P SW
Sbjct: 4050 GSASSSTSL------KVKEP-----PIFRKKPHPIETLKGADVHLECELQGTPPFHVSWY 4098
Query: 131 KDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG 176
KD + + + E + + I V D+G Y+ N++G
Sbjct: 4099 KDKRELRSGKKYKIM-SENFLTSIHILNVDAADIGEYQCKATNDVG 4143
Score = 76.6 bits (180), Expect = 6e-14
Identities = 54/182 (29%), Positives = 85/182 (46%), Gaps = 13/182 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G++ +FEC VTG I W + IR ++ + T L+I +V D G YTC+
Sbjct: 2950 GESADFECHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYTCQ 3009
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYT-YPFNKVVEEGENVTFKCAVKGNPS 124
A+N +GK +A L V + P F +KV ++GE++ +C + G+P
Sbjct: 3010 ATNDVGKDMCSAQLSV-----------KEPPKFVKKLEASKVAKQGESIQLECKISGSPE 3058
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
SW ++ S + S + + + +L I+E S ED G Y N +G A S L
Sbjct: 3059 IKVSWFRNDSELHESWKYNMSFINSV-ALLTINEASAEDSGDYICEAHNGVGDASCSTAL 3117
Query: 185 EV 186
V
Sbjct: 3118 TV 3119
Score = 74.1 bits (174), Expect = 3e-13
Identities = 51/180 (28%), Positives = 79/180 (43%), Gaps = 12/180 (6%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G + FECQ+TG P + W+ I S+ DG A +I E+ GTY C
Sbjct: 1540 NGQSTTFECQITGTPKIRVSWYLDGNEITAIQKHGISFIDGLATFQISGARVENSGTYVC 1599
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
EA N G A +C + + + R++ P +VV+ + V +C V G P
Sbjct: 1600 EARNDAGTA---SCSIELKVKEPPTFIRELKPV-------EVVKYSD-VELECEVTGTPP 1648
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
+W K+ I S + T+ ++ + L I + D G Y+ V NE G S R+
Sbjct: 1649 FEVTWLKNNREIRSSKKYTLTDRVSVFN-LHITKCDPSDTGEYQCIVSNEGGSCSCSTRV 1707
Score = 73.3 bits (172), Expect = 6e-13
Identities = 51/186 (27%), Positives = 89/186 (47%), Gaps = 13/186 (6%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G V F+C ++G+ + W+ + ++D + ++S+ D TA L I + G Y+C
Sbjct: 4736 GLPVVFDCAISGSEPISVSWYKDGKPLKDSPNVQTSFLDNTATLNIFKTDRSLAGQYSCT 4795
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A+N +G A S+A L++ + ++AP + VV GE+ F+C V G
Sbjct: 4796 ATNPIGSASSSARLILTEGKNPPFFDIRLAPV------DAVV--GESADFECHVTGTQPI 4847
Query: 126 WASWDKDGSIITPSAR--ITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
SW KD I + I+ E + +L++D+ D G Y NE+G+ +A+
Sbjct: 4848 KVSWAKDSREIRSGGKYQISYLENSAHLTVLKVDK---GDSGQYTCYAVNEVGKDSCTAQ 4904
Query: 184 LEVITR 189
L + R
Sbjct: 4905 LNIKER 4910
Score = 72.5 bits (170), Expect = 1e-12
Identities = 51/179 (28%), Positives = 76/179 (42%), Gaps = 12/179 (6%)
Query: 8 TVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEAS 67
T +C++ G+ + WF + I + ++ +GTA L+I +V D G +TC A+
Sbjct: 794 TCRLDCKIAGSLPMRVSWFKDGKEIAASDRYRIAFVEGTASLEIIRVDMNDAGNFTCRAT 853
Query: 68 NCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWA 127
N +G S+ L+V Q P+F T P +K V G V K +G+
Sbjct: 854 NSVGSKDSSGALIV-----------QEPPSFVTKPGSKDVLPGSAVCLKSTFQGSTPLTI 902
Query: 128 SWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W K + + KE + LE+ V D G Y V N G E SA L V
Sbjct: 903 RWFKGNKELVSGGSCYI-TKEALESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFV 960
Score = 72.1 bits (169), Expect = 1e-12
Identities = 54/186 (29%), Positives = 79/186 (42%), Gaps = 12/186 (6%)
Query: 1 MLSCDGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEG 60
M S G ++ EC V G+ I+WF + I ++ S+ D TA L+I Q+ D G
Sbjct: 1349 MDSIKGSFIDLECIVAGSHPISIQWFKDDQEISASEKYKFSFHDNTAFLEISQLEGTDSG 1408
Query: 61 TYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVK 120
TYTC A+N G + + L V + P F P ++ V V K V
Sbjct: 1409 TYTCSATNKAGHNQCSGHLTV-----------KEPPYFVEKPQSQDVNPNTRVQLKALVG 1457
Query: 121 GNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEA 180
G W KD + A +V K++ LE+ D G Y + N++G A +
Sbjct: 1458 GTAPMTIKWFKDNKELHSGAARSV-WKDDTSTSLELFAAKATDSGTYICQLSNDVGTATS 1516
Query: 181 SARLEV 186
A L V
Sbjct: 1517 KATLFV 1522
Score = 72.1 bits (169), Expect = 1e-12
Identities = 48/180 (26%), Positives = 78/180 (43%), Gaps = 12/180 (6%)
Query: 11 FECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCL 70
F+ V G+P I W +++ + + S+ D A L+I+ V G YTC+A N
Sbjct: 1732 FQSTVAGSPPISITWLKDDQILDEDDNVYISFVDSVATLQIRSVDNGHSGRYTCQAKNES 1791
Query: 71 GKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWD 130
G + A L+V ++ + + V E + +T +C V G P W
Sbjct: 1792 GVERCYAFLLVQEPAQIVEKAKSVD-----------VTEKDPMTLECVVAGTPELKVKWL 1840
Query: 131 KDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVITRS 190
KDG I PS ++ + + I V +D G Y VEN+ G + A L V+ ++
Sbjct: 1841 KDGKQIVPSRYFSMSFENNVAS-FRIQSVMKQDSGQYTFKVENDFGSSSCDAYLRVLDQN 1899
Score = 71.7 bits (168), Expect = 2e-12
Identities = 51/180 (28%), Positives = 83/180 (46%), Gaps = 14/180 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
GD + C+VTG P I WF I++ + S+ + TA L++ V ED G Y CE
Sbjct: 979 GDATQLACKVTGTPPIKITWFANDREIKESSKHRMSFVESTAVLRLTDVGIEDSGEYMCE 1038
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKV-VEEGENVTFKCAVKGNPS 124
A N G ++ ++V SP ++T F + V + +V V G P
Sbjct: 1039 AQNEAGSDHCSSIVIV-----KESP-------YFTKEFKPIEVLKEYDVMLLAEVAGTPP 1086
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
+W KD +I+ + ++ ++ L+I + D G Y+ V NE+G + SAR+
Sbjct: 1087 FEITWFKDNTILRSGRKYKTFIQDHLVS-LQILKFVAADAGEYQCRVTNEVGSSICSARV 1145
Score = 71.7 bits (168), Expect = 2e-12
Identities = 51/183 (27%), Positives = 77/183 (42%), Gaps = 14/183 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G V F V G P + WF + + S +D A L++ V G YTC
Sbjct: 4454 GTNVTFTSIVKGTPPFSVSWFKGSSELVPGDRCNVSLEDSVAELELFDVDTSQSGEYTCI 4513
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKV-VEEGENVTFKCAVKGNPS 124
SN GKA L + AP + N +E+G+ + + G P
Sbjct: 4514 VSNEAGKASCTTHLYI------------KAPAKFVKRLNDYSIEKGKPLILEGTFTGTPP 4561
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
+W K+G +TPS R + E+ ILEI ++ED G Y +EN G+ SA++
Sbjct: 4562 ISVTWKKNGINVTPSQRCNITTTEK-SPILEIPSSTVEDAGQYNCYIENASGKDSCSAQI 4620
Query: 185 EVI 187
++
Sbjct: 4621 LIL 4623
Score = 70.5 bits (165), Expect = 4e-12
Identities = 50/181 (27%), Positives = 79/181 (43%), Gaps = 11/181 (6%)
Query: 7 DTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEA 66
D + EC V G P+ ++W + I F S+++ A +I+ V +D G YT +
Sbjct: 1821 DPMTLECVVAGTPELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSGQYTFKV 1880
Query: 67 SNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEE-GENVTFKCAVKGNPSP 125
N G + +A L V Q P +T K+ + G ++ +C V G+
Sbjct: 1881 ENDFGSSSCDAYLRVLD---------QNIPPSFTKKLTKMDKVLGSSIHMECKVSGSLPI 1931
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
A W KDG I+ SA+ + E + LE++ + +ED Y V N G S L
Sbjct: 1932 SAQWFKDGKEISTSAKYRLVCHERSVS-LEVNNLELEDTANYTCKVSNVAGDDACSGILT 1990
Query: 186 V 186
V
Sbjct: 1991 V 1991
Score = 70.1 bits (164), Expect = 6e-12
Identities = 46/178 (25%), Positives = 80/178 (44%), Gaps = 11/178 (6%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
V ECQV + + W + + D++ ++D A L+I +D GTY C ASN
Sbjct: 326 VHLECQVDEDRKVTVTWSKDGQKLPPGKDYKICFEDKIATLEIPLAKLKDSGTYVCTASN 385
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
+A S++C R S +++ P++ P GE+ C +KG+P +
Sbjct: 386 ---EAGSSSCSATVTVREPPSFVKKVDPSYLMLP-------GESARLHCKLKGSPVIQVT 435
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W K+ ++ S + + IL+I +V +ED G Y N++G S + +
Sbjct: 436 WFKNNKELSESNTVRMYFVNS-EAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVI 492
Score = 70.1 bits (164), Expect = 6e-12
Identities = 49/181 (27%), Positives = 76/181 (41%), Gaps = 12/181 (6%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G +V EC+V+G+ + WF I +SS+ + L + + D G YTC
Sbjct: 3420 GASVVLECRVSGSAPISVGWFQDGNEIVSGPKCQSSFSENVCTLNLSLLEPSDTGIYTCV 3479
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A+N G + +A L V Q P+F P + V G ++TF ++G P
Sbjct: 3480 AANVAGSDECSAVLTV-----------QEPPSFEQTPDSVEVLPGMSLTFTSVIRGTPPF 3528
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
W K + P + E+ + LE+ EV + G Y V N+ G A + L
Sbjct: 3529 KVKWFKGSRELVPGESCNI-SLEDFVTELELFEVQPLESGDYSCLVTNDAGSASCTTHLF 3587
Query: 186 V 186
V
Sbjct: 3588 V 3588
Score = 68.9 bits (161), Expect = 1e-11
Identities = 53/193 (27%), Positives = 83/193 (43%), Gaps = 10/193 (5%)
Query: 2 LSCDGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGT 61
++ +G F+C+V+G D + W+ + I+ F + + T +L+I + EDEGT
Sbjct: 20 VTSEGQPARFQCRVSGT-DLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGT 78
Query: 62 YTCEASNCLGKAKSNACL------VVYHTRRLSSPGRQM--APTFYTYPFNKVVEEGENV 113
YT A+N +G+ S A L + H R +M AP V G
Sbjct: 79 YTFVANNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKAAPVIKRKIEPLEVALGHLA 138
Query: 114 TFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVEN 173
F C ++ P+ W K G I S + +++ + I LEI + D G Y N
Sbjct: 139 KFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISS-LEILRTQVVDCGEYTCKASN 197
Query: 174 ELGRAEASARLEV 186
E G +A L V
Sbjct: 198 EYGSVSCTATLTV 210
Score = 68.9 bits (161), Expect = 1e-11
Identities = 48/186 (25%), Positives = 79/186 (42%), Gaps = 13/186 (6%)
Query: 6 GDTVEFECQVTGNPDPDIRWFH-YAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
G V+ + + G + WF E++R+ + SY + A L+ +V + G YTC
Sbjct: 4171 GKEVQLQTTIEGAEPISVVWFKDKGEIVRESDNIWISYSENIATLQFSRVEPANAGKYTC 4230
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
+ N G + A L V T P + V G+ T +C V G P
Sbjct: 4231 QIKNDAGMQECFATLSVLEPA-----------TIVEKPESIKVTTGDTCTLECTVAGTPE 4279
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
W KDG +T + + ++ L+I V+ D G+Y V+N +G+ +A L
Sbjct: 4280 LSTKWFKDGKELTSDNKYKISFFNKVSG-LKIINVAPSDSGVYSFEVQNPVGKDSCTASL 4338
Query: 185 EVITRS 190
+V R+
Sbjct: 4339 QVSDRT 4344
Score = 66.1 bits (154), Expect = 9e-11
Identities = 47/189 (24%), Positives = 74/189 (39%), Gaps = 12/189 (6%)
Query: 1 MLSCDGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEG 60
+++ G TV + V G+ + W EVIR+ + S+ +G A L I V G
Sbjct: 598 LIALGGQTVTLQAAVRGSEPISVTWMKGQEVIREDGKIKMSFSNGVAVLIIPDVQISFGG 657
Query: 61 TYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVK 120
YTC A N G S L+V ++ + V G+ T + V
Sbjct: 658 KYTCLAENEAGSQTSVGELIVKEPAKIIERAELIQ-----------VTAGDPATLEYTVA 706
Query: 121 GNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEA 180
G P W KDG + S + + K + + L+ + D G Y + NE+G +
Sbjct: 707 GTPELKPKWYKDGRPLVASKKYRISFKNNVAQ-LKFYSAELHDSGQYTFEISNEVGSSSC 765
Query: 181 SARLEVITR 189
V+ R
Sbjct: 766 ETTFTVLDR 774
Score = 66.1 bits (154), Expect = 9e-11
Identities = 48/178 (26%), Positives = 77/178 (43%), Gaps = 11/178 (6%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
V+ + V G I+WF + + A DD + L++ A D GTY C+ SN
Sbjct: 1450 VQLKALVGGTAPMTIKWFKDNKELHSGAARSVWKDDTSTSLELFAAKATDSGTYICQLSN 1509
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
+G A S A L V + ++ +P V+ G++ TF+C + G P S
Sbjct: 1510 DVGTATSKATLFVKEPPQFI---KKPSPVL-------VLRNGQSTTFECQITGTPKIRVS 1559
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W DG+ IT + + + + +I +E+ G Y N+ G A S L+V
Sbjct: 1560 WYLDGNEITAIQKHGISFIDG-LATFQISGARVENSGTYVCEARNDAGTASCSIELKV 1616
Score = 66.1 bits (154), Expect = 9e-11
Identities = 42/173 (24%), Positives = 76/173 (43%), Gaps = 16/173 (9%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
GD+ EC++ G+P+ + WF + + ++ D A +++ ++ ED G + CE
Sbjct: 2103 GDSSRLECKIAGSPEIRVVWFRNEHELPASDKYRMTFIDSVAVIQMNNLSTEDSGDFICE 2162
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGEN--VTFKCAVKGNP 123
A N G + ++V + P F ++P +VE +N V+ +C + G P
Sbjct: 2163 AQNPAGSTSCSTKVIV-----------KEPPVFSSFP--PIVETLKNAEVSLECELSGTP 2209
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG 176
W KD + S + + K + I V D+G Y +NE+G
Sbjct: 2210 PFEVVWYKDKRQLRSSKKYKIASK-NFHTSIHILNVDTSDIGEYHCKAQNEVG 2261
Score = 66.1 bits (154), Expect = 9e-11
Identities = 46/188 (24%), Positives = 81/188 (43%), Gaps = 17/188 (9%)
Query: 6 GDTVEFECQVTGNPDPDIRWF-HYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
G+ E + + G ++W EVIR+ + ++ + A L+ + + G Y C
Sbjct: 2289 GEPAELQASIEGAQPIFVQWLKEKEEVIRESENIRITFVENVATLQFAKAEPANAGKYIC 2348
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
+ N G ++ A L+V + M T GE T +C V G P
Sbjct: 2349 QIKNDGGMRENMATLMVLEPAVIVEKAGPMTVTV-----------GETCTLECKVAGTPE 2397
Query: 125 PWASWDKDGSIITPSA--RITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASA 182
W KDG ++T S + + K +RIL ++ +D G Y V+N +G++ +A
Sbjct: 2398 LSVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVER---QDAGTYTFQVQNNVGKSSCTA 2454
Query: 183 RLEVITRS 190
++V R+
Sbjct: 2455 VVDVSDRA 2462
Score = 65.7 bits (153), Expect = 1e-10
Identities = 49/181 (27%), Positives = 75/181 (41%), Gaps = 9/181 (4%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
GDT EC V G P+ +WF + + ++ S+ + + LKI V D G Y+ E
Sbjct: 4265 GDTCTLECTVAGTPELSTKWFKDGKELTSDNKYKISFFNKVSGLKIINVAPSDSGVYSFE 4324
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
N +GK ++C T L R + P+F G +V +C V G+P
Sbjct: 4325 VQNPVGK---DSC-----TASLQVSDRTVPPSFTRKLKETNGLSGSSVVMECKVYGSPPI 4376
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
SW +G+ I+ + + L ++ + D G Y N G E SA L
Sbjct: 4377 SVSWFHEGNEISSGRKYQTTLTDNTC-ALTVNMLEESDSGDYTCIATNMAGSDECSAPLT 4435
Query: 186 V 186
V
Sbjct: 4436 V 4436
Score = 64.1 bits (149), Expect = 4e-10
Identities = 46/181 (25%), Positives = 76/181 (41%), Gaps = 12/181 (6%)
Query: 2 LSCDGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGT 61
L G++ C++ G+P + WF + + + + + A L I V ED G+
Sbjct: 413 LMLPGESARLHCKLKGSPVIQVTWFKNNKELSESNTVRMYFVNSEAILDITDVKVEDSGS 472
Query: 62 YTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKG 121
Y+CEA N +G + +V+ + P+F + G N +C V G
Sbjct: 473 YSCEAVNDVGSDSCSTEIVI-----------KEPPSFIKTLEPADIVRGTNALLQCEVSG 521
Query: 122 NPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEAS 181
SW KD I S + + ++ ++ LEI + DVG Y V NE+G+
Sbjct: 522 TGPFEISWFKDKKQIRSSKKYRLFSQKSLV-CLEIFSFNSADVGEYECVVANEVGKCGCM 580
Query: 182 A 182
A
Sbjct: 581 A 581
Score = 64.1 bits (149), Expect = 4e-10
Identities = 44/182 (24%), Positives = 80/182 (43%), Gaps = 9/182 (4%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G++ + E +V G+ + W+ I+ ++ E ++ + T L++++ D G YTC
Sbjct: 4928 EGNSFKLEGRVAGSQPITVAWYKNNIEIQPTSNCEITFKNNTLVLQVRKAGMNDAGLYTC 4987
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
+ SN G A + +V+ ++ P F + V EGE V C V+G+
Sbjct: 4988 KVSNDAGSALCTSSIVIKEPKK--------PPVFDQHLTPVTVSEGEYVQLSCHVQGSEP 5039
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
W K G I PS R + +LE+ +V+ D G Y N G +++
Sbjct: 5040 IRIQWLKAGREIKPSDRCSFSFASG-TAVLELRDVAKADSGDYVCKASNVAGSDTTKSKV 5098
Query: 185 EV 186
+
Sbjct: 5099 TI 5100
Score = 63.7 bits (148), Expect = 5e-10
Identities = 47/185 (25%), Positives = 75/185 (40%), Gaps = 13/185 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFH-YAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
GD VE V G + W EVIR+ + S+ D A L++ A + G Y C
Sbjct: 3230 GDAVELRAIVEGFQPISVVWLKDRGEVIRESENTRISFIDNIATLQLGSPEASNSGKYIC 3289
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
+ N G + +A L V R+ M V G +C V G P
Sbjct: 3290 QIKNDAGMRECSAVLTVLEPARIIEKPEPM-----------TVTTGNPFALECVVTGTPE 3338
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
A W KDG ++ ++ + ++ L+I + D G+Y V+N +G++ + +
Sbjct: 3339 LSAKWFKDGRELSADSKHHITFINKVAS-LKIPCAEMSDKGLYSFEVKNSVGKSNCTVSV 3397
Query: 185 EVITR 189
V R
Sbjct: 3398 HVSDR 3402
Score = 63.3 bits (147), Expect = 6e-10
Identities = 41/185 (22%), Positives = 80/185 (43%), Gaps = 12/185 (6%)
Query: 3 SCDGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTY 62
S G T F+ + G+ + W ++ I + + ++++ A L + + + +G Y
Sbjct: 1162 SLRGGTAAFQATLKGSLPITVTWLKDSDEITEDDNIRMTFENNVASLYLSGIEVKHDGKY 1221
Query: 63 TCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGN 122
C+A N G + +A L V ++ + V +G+ T + G
Sbjct: 1222 VCQAKNDAGIQRCSALLSVKEPATITEEAVSID-----------VTQGDPATLQVKFSGT 1270
Query: 123 PSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASA 182
A W KDG +T ++ + + + IL+I +D G Y V+N++GR+ A
Sbjct: 1271 KEITAKWFKDGQELTLGSKYKISVTDTV-SILKIISTEKKDSGEYTFEVQNDVGRSSCKA 1329
Query: 183 RLEVI 187
R+ V+
Sbjct: 1330 RINVL 1334
Score = 63.3 bits (147), Expect = 6e-10
Identities = 48/181 (26%), Positives = 72/181 (39%), Gaps = 9/181 (4%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+ EC VTG P+ +WF + + ++ + A LKI D+G Y+ E
Sbjct: 3324 GNPFALECVVTGTPELSAKWFKDGRELSADSKHHITFINKVASLKIPCAEMSDKGLYSFE 3383
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
N +GK+ C V H R + P+F + G +V +C V G+
Sbjct: 3384 VKNSVGKSN---CTVSVHV-----SDRIVPPSFIRKLKDVNAILGASVVLECRVSGSAPI 3435
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
W +DG+ I + E + L + + D GIY N G E SA L
Sbjct: 3436 SVGWFQDGNEIVSGPKCQSSFSENVC-TLNLSLLEPSDTGIYTCVAANVAGSDECSAVLT 3494
Query: 186 V 186
V
Sbjct: 3495 V 3495
Score = 62.5 bits (145), Expect = 1e-09
Identities = 43/181 (23%), Positives = 77/181 (42%), Gaps = 9/181 (4%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+T EC+V G P+ + W+ +++ + S+ + + L+I V +D GTYT +
Sbjct: 2383 GETCTLECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVERQDAGTYTFQ 2442
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
N +GK+ A + V R + P+F N G + +C V G+
Sbjct: 2443 VQNNVGKSSCTAVVDV--------SDRAVPPSFTRRLKNTGGVLGASCILECKVAGSSPI 2494
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
+W + + I A+ + + L+++ + D+G Y N G E A L
Sbjct: 2495 SVAWFHEKTKIVSGAKYQTTFSDNVC-TLQLNSLDSSDMGNYTCVAANVAGSDECRAVLT 2553
Query: 186 V 186
V
Sbjct: 2554 V 2554
Score = 61.7 bits (143), Expect = 2e-09
Identities = 49/182 (26%), Positives = 76/182 (41%), Gaps = 12/182 (6%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G ++ F + G P ++WF + + S +D L++ +V + G Y+C
Sbjct: 3513 GMSLTFTSVIRGTPPFKVKWFKGSRELVPGESCNISLEDFVTELELFEVQPLESGDYSCL 3572
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
+N G A L V P TF + VE G + + G P
Sbjct: 3573 VTNDAGSASCTTHLFV------KEPA-----TFVKRLADFSVETGSPIVLEATYTGTPPI 3621
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
SW KD +I+ S R ++ E+ ILEI E +IED Y +ENE G+ A +
Sbjct: 3622 SVSWIKDEYLISQSERCSITMTEK-STILEILESTIEDYAQYSCLIENEAGQDICEALVS 3680
Query: 186 VI 187
V+
Sbjct: 3681 VL 3682
Score = 59.7 bits (138), Expect = 8e-09
Identities = 46/181 (25%), Positives = 75/181 (41%), Gaps = 12/181 (6%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G +F C VTG P + W + ++ S + L++ +T +D G Y+C+
Sbjct: 230 GKAAKFICTVTGTPVIETIWQKDGAALSPSPNWRISDAENKHILELSNLTIQDRGVYSCK 289
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
ASN G A L++ +++ P NK V +C V +
Sbjct: 290 ASNKFGADICQAELIIIDKPHFI---KELEPV--QSAINK------KVHLECQVDEDRKV 338
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
+W KDG + P + +++I LEI ++D G Y T NE G + SA +
Sbjct: 339 TVTWSKDGQKLPPGKDYKICFEDKI-ATLEIPLAKLKDSGTYVCTASNEAGSSSCSATVT 397
Query: 186 V 186
V
Sbjct: 398 V 398
Score = 59.7 bits (138), Expect = 8e-09
Identities = 48/182 (26%), Positives = 70/182 (38%), Gaps = 12/182 (6%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G V F + G P + WF A + ++D A L++ + G YTC
Sbjct: 2572 GKNVTFTSVIRGTPPFKVNWFRGARELVKGDRCNIYFEDTVAELELFNIDISQSGEYTCV 2631
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
SN G+A L V P F + VE G+++ + G
Sbjct: 2632 VSNNAGQASCTTRLFV------KEPA-----AFLKRLSDHSVEPGKSIILESTYTGTLPI 2680
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
+W KDG IT S + + E+ ILEI + D G Y +ENE GR A +
Sbjct: 2681 SVTWKKDGFNITTSEKCNIVTTEKTC-ILEILNSTKRDAGQYSCEIENEAGRDVCGALVS 2739
Query: 186 VI 187
+
Sbjct: 2740 TL 2741
Score = 58.4 bits (135), Expect = 2e-08
Identities = 45/194 (23%), Positives = 76/194 (39%), Gaps = 13/194 (6%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G ++ EC+V+G+ +WF + I A + + + L++ + ED YTC+
Sbjct: 1916 GSSIHMECKVSGSLPISAQWFKDGKEISTSAKYRLVCHERSVSLEVNNLELEDTANYTCK 1975
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
SN G + L V + P+F P + V FK +KG P
Sbjct: 1976 VSNVAGDDACSGILTV-----------KEPPSFLVKPGRQQAIPDSTVEFKAILKGTPPF 2024
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
W KD + + + E L + V G Y V N++G +++ +
Sbjct: 2025 KIKWFKDDVELVSGPKCFI-GLEGSTSFLNLYSVDASKTGQYTCHVTNDVG-SDSCTTML 2082
Query: 186 VITRSGKFYGGLRA 199
++T KF L A
Sbjct: 2083 LVTEPPKFVKKLEA 2096
Score = 57.2 bits (132), Expect = 4e-08
Identities = 47/181 (25%), Positives = 72/181 (39%), Gaps = 12/181 (6%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G +C+V+G +I WF + IR + L+I + D G Y C
Sbjct: 510 GTNALLQCEVSGTGPFEISWFKDKKQIRSSKKYRLFSQKSLVCLEIFSFNSADVGEYECV 569
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
+N +GK C+ T L P PTF + + G+ VT + AV+G+
Sbjct: 570 VANEVGKC---GCMA---THLLKEP-----PTFVKKVDDLIALGGQTVTLQAAVRGSEPI 618
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
+W K +I +I + + +L I +V I G Y ENE G + L
Sbjct: 619 SVTWMKGQEVIREDGKIKMSFSNGV-AVLIIPDVQISFGGKYTCLAENEAGSQTSVGELI 677
Query: 186 V 186
V
Sbjct: 678 V 678
Score = 55.2 bits (127), Expect = 2e-07
Identities = 45/183 (24%), Positives = 74/183 (40%), Gaps = 13/183 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G V EC++ G P + W+ +R ++ ++ + I V A D G Y C+
Sbjct: 4078 GADVHLECELQGTPPFHVSWYKDKRELRSGKKYKIMSENFLTSIHILNVDAADIGEYQCK 4137
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A+N +G S+ C + S + P F + G+ V + ++G
Sbjct: 4138 ATNDVG---SDTC--------VGSIALKAPPRFVKKLSDISTVVGKEVQLQTTIEGAEPI 4186
Query: 126 WASWDKD-GSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
W KD G I+ S I + E I L+ V + G Y ++N+ G E A L
Sbjct: 4187 SVVWFKDKGEIVRESDNIWISYSENI-ATLQFSRVEPANAGKYTCQIKNDAGMQECFATL 4245
Query: 185 EVI 187
V+
Sbjct: 4246 SVL 4248
Score = 54.0 bits (124), Expect = 4e-07
Identities = 44/185 (23%), Positives = 74/185 (40%), Gaps = 14/185 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G + E TG P + W +I + + + L+I + T ED Y+C
Sbjct: 3606 GSPIVLEATYTGTPPISVSWIKDEYLISQSERCSITMTEKSTILEILESTIEDYAQYSCL 3665
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKV-VEEGENVTFKCAVKGNPS 124
N G+ A + V + P ++ P V GE T +C V G P
Sbjct: 3666 IENEAGQDICEALVSV------------LEPPYFIEPLEHVEAVIGEPATLQCKVDGTPE 3713
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
SW K+ + + + ++ K + ++ I++V DVG Y +N +G +SA L
Sbjct: 3714 IRISWYKEHTKLRSAPAYKMQFKNNVASLV-INKVDHSDVGEYSCKADNSVGAVASSAVL 3772
Query: 185 EVITR 189
+ R
Sbjct: 3773 VIKAR 3777
Score = 53.6 bits (123), Expect = 5e-07
Identities = 41/182 (22%), Positives = 71/182 (39%), Gaps = 14/182 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G + E TG P + W + + + + L+I T ED G Y C
Sbjct: 4547 GKPLILEGTFTGTPPISVTWKKNGINVTPSQRCNITTTEKSPILEIPSSTVEDAGQYNCY 4606
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKV-VEEGENVTFKCAVKGNPS 124
N GK +A +++ + P ++ V V G++ + +C + G P
Sbjct: 4607 IENASGKDSCSAQILI------------LEPPYFVKQLEPVKVSVGDSASLQCQLAGTPE 4654
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
SW K + + P+ + + + ++ ++V I D G Y EN +G AS L
Sbjct: 4655 IGVSWYKGDTKLRPTTTYKMHFRNNVATLV-FNQVDINDSGEYICKAENSVGEVSASTFL 4713
Query: 185 EV 186
V
Sbjct: 4714 TV 4715
Score = 50.4 bits (115), Expect = 5e-06
Identities = 42/181 (23%), Positives = 79/181 (43%), Gaps = 15/181 (8%)
Query: 8 TVEFECQVTGNPDPDIRWFHY-AEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEA 66
TVEF+ + G P I+WF E++ F + T+ L + V A G YTC
Sbjct: 2011 TVEFKAILKGTPPFKIKWFKDDVELVSGPKCF-IGLEGSTSFLNLYSVDASKTGQYTCHV 2069
Query: 67 SNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYT-YPFNKVVEEGENVTFKCAVKGNPSP 125
+N +G L+V + P P F +K+V+ G++ +C + G+P
Sbjct: 2070 TNDVGSDSCTTMLLV------TEP-----PKFVKKLEASKIVKAGDSSRLECKIAGSPEI 2118
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
W ++ + S + + + + +++++ +S ED G + +N G S ++
Sbjct: 2119 RVVWFRNEHELPASDKYRMTFIDSV-AVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVI 2177
Query: 186 V 186
V
Sbjct: 2178 V 2178
Score = 48.8 bits (111), Expect = 1e-05
Identities = 42/168 (25%), Positives = 62/168 (36%), Gaps = 12/168 (7%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
VE EC+VTG P ++ W IR + + L I + D G Y C SN
Sbjct: 1637 VELECEVTGTPPFEVTWLKNNREIRSSKKYTLTDRVSVFNLHITKCDPSDTGEYQCIVSN 1696
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G + + L P P+F N + TF+ V G+P +
Sbjct: 1697 EGGSCSCSTRVA------LKEP-----PSFIKKIENTTTVLKSSATFQSTVAGSPPISIT 1745
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG 176
W KD I+ + + + + L+I V G Y +NE G
Sbjct: 1746 WLKDDQILDEDDNVYISFVDSV-ATLQIRSVDNGHSGRYTCQAKNESG 1792
Score = 46.0 bits (104), Expect = 1e-04
Identities = 42/184 (22%), Positives = 67/184 (36%), Gaps = 12/184 (6%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G ++ E TG + W I + T L+I T D G Y+CE
Sbjct: 2665 GKSIILESTYTGTLPISVTWKKDGFNITTSEKCNIVTTEKTCILEILNSTKRDAGQYSCE 2724
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
N G+ + C + T P F T G++V+ +C V G P
Sbjct: 2725 IENEAGR---DVCGALVSTLE--------PPYFVTELEPLEAAVGDSVSLQCQVAGTPEI 2773
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
SW K + + P+ + ++ ++V+I D G Y EN +G A +
Sbjct: 2774 TVSWYKGDTKLRPTPEYRTYFTNNVATLV-FNKVNINDSGEYTCKAENSIGTASSKTVFR 2832
Query: 186 VITR 189
+ R
Sbjct: 2833 IQER 2836
Score = 44.0 bits (99), Expect = 4e-04
Identities = 40/176 (22%), Positives = 75/176 (42%), Gaps = 19/176 (10%)
Query: 19 PDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLGKAKSNA- 77
P+ WF +++ ++ + +L I V AED+G YTC+ + A+
Sbjct: 5436 PNVKSEWFRNGRILKPQGRHKTEVEHKVHKLTIADVRAEDQGQYTCKYEDLETSAELRIE 5495
Query: 78 CLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIIT 137
+ T+R+ N VV E ++ TF+C V + + +W K + +T
Sbjct: 5496 AEPIQFTKRIQ---------------NIVVSEHQSATFECEVSFDDA-IVTWYKGPTELT 5539
Query: 138 PSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENE-LGRAEASARLEVITRSGK 192
S + + + + I V+ +D G+Y + E G A ++A L + T+ K
Sbjct: 5540 ESQKYNFR-NDGRCHYMTIHNVTPDDEGVYSVIARLEPRGEARSTAELYLTTKEIK 5594
Score = 40.7 bits (91), Expect = 0.004
Identities = 27/91 (29%), Positives = 39/91 (42%), Gaps = 2/91 (2%)
Query: 96 PTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILE 155
P T + V EG+ F+C V G SW I PS + + E+ + LE
Sbjct: 10 PAIITPLQDTVTSEGQPARFQCRVSGTDLK-VSWYSKDKKIKPSRFFRMTQFEDTYQ-LE 67
Query: 156 IDEVSIEDVGIYRITVENELGRAEASARLEV 186
I E ED G Y N +G+ ++A L +
Sbjct: 68 IAEAYPEDEGTYTFVANNAVGQVSSTANLSL 98
Score = 39.9 bits (89), Expect = 0.007
Identities = 44/184 (23%), Positives = 73/184 (39%), Gaps = 20/184 (10%)
Query: 5 DGDTVEFECQVTGN-PDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYT 63
D D V FE + N P+ + W+ E + FE S D L++K +D+G Y
Sbjct: 5335 DNDAV-FEIDIKINYPEIKLSWYKGTEKLEPSDKFEISIDGDRHTLRVKNCQLKDQGNYR 5393
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
+ AK L V + P + + + ++EG+ T P
Sbjct: 5394 LVCGPHIASAK----LTV------------IEPAWERHLQDVTLKEGQTCTMTVQF-SVP 5436
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
+ + W ++G I+ P R + + ++ + L I +V ED G Y E+ AE
Sbjct: 5437 NVKSEWFRNGRILKPQGRHKTEVEHKVHK-LTIADVRAEDQGQYTCKYEDLETSAELRIE 5495
Query: 184 LEVI 187
E I
Sbjct: 5496 AEPI 5499
Score = 29.5 bits (63), Expect = 9.6
Identities = 19/68 (27%), Positives = 32/68 (47%), Gaps = 2/68 (2%)
Query: 11 FECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEAS-NC 69
FEC+V+ + D + W+ + + + D + I VT +DEG Y+ A
Sbjct: 5518 FECEVSFD-DAIVTWYKGPTELTESQKYNFRNDGRCHYMTIHNVTPDDEGVYSVIARLEP 5576
Query: 70 LGKAKSNA 77
G+A+S A
Sbjct: 5577 RGEARSTA 5584
>AJ277892-2|CAD12456.1|30017|Homo sapiens Titin protein.
Length = 30000
Score = 93.9 bits (223), Expect = 4e-19
Identities = 64/203 (31%), Positives = 87/203 (42%), Gaps = 13/203 (6%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G +V EC+V G+P + WFH I ++++ D T L + + D G YTC
Sbjct: 8623 GSSVVMECKVYGSPPISVSWFHEGNEISSGRKYQTTLTDNTCALTVNMLEESDSGDYTCI 8682
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A+N G + +A L V + P+F P V G NVTF VKG P
Sbjct: 8683 ATNMAGSDECSAPLTV-----------REPPSFVQKPDPMDVLTGTNVTFTSIVKGTPPF 8731
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
SW K S + P R V ++ + LE+ +V G Y V NE G+A + L
Sbjct: 8732 SVSWFKGSSELVPGDRCNVSLEDSVAE-LELFDVDTSQSGEYTCIVSNEAGKASCTTHL- 8789
Query: 186 VITRSGKFYGGLRAYSASPRKCL 208
I KF L YS K L
Sbjct: 8790 YIKAPAKFVKRLNDYSIEKGKPL 8812
Score = 87.4 bits (207), Expect = 3e-17
Identities = 57/184 (30%), Positives = 92/184 (50%), Gaps = 11/184 (5%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCA--DFESSYDDGTARLKIKQVTAEDEGTY 62
+G T FE ++G P P++ WF +VI + S+ DG A+L I VT + G Y
Sbjct: 19 EGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKANSGRY 78
Query: 63 TCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGN 122
+ +A+N G+A S A L+V + ++P P F + V +G V + V G
Sbjct: 79 SLKATNGSGQATSTAELLV---KAETAP-----PNFVQRLQSMTVRQGSQVRLQVRVTGI 130
Query: 123 PSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASA 182
P+P + +DG+ I S + ++ ++ +L I E ED G Y + N +GRA ++A
Sbjct: 131 PTPVVKFYRDGAEIQSSLDFQISQEGDLYSLL-IAEAYPEDSGTYSVNATNSVGRATSTA 189
Query: 183 RLEV 186
L V
Sbjct: 190 ELLV 193
Score = 81.8 bits (193), Expect = 2e-15
Identities = 53/203 (26%), Positives = 86/203 (42%), Gaps = 13/203 (6%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G + EC+V G+ + WFH I A +++++ D L++ + + D G YTC
Sbjct: 6741 GASCILECKVAGSSPISVAWFHEKTKIVSGAKYQTTFSDNVCTLQLNSLDSSDMGNYTCV 6800
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A+N G + A L V Q P+F P V G+NVTF ++G P
Sbjct: 6801 AANVAGSDECRAVLTV-----------QEPPSFVKEPEPLEVLPGKNVTFTSVIRGTPPF 6849
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
+W + + R + ++ + LE+ + I G Y V N G+A + RL
Sbjct: 6850 KVNWFRGARELVKGDRCNIYFEDTVAE-LELFNIDISQSGEYTCVVSNNAGQASCTTRL- 6907
Query: 186 VITRSGKFYGGLRAYSASPRKCL 208
+ F L +S P K +
Sbjct: 6908 FVKEPAAFLKRLSDHSVEPGKSI 6930
Score = 81.0 bits (191), Expect = 3e-15
Identities = 51/180 (28%), Positives = 82/180 (45%), Gaps = 11/180 (6%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+ +C+V G P+ I W+ +R ++ + + A L I +V D G Y+C+
Sbjct: 7961 GEPATLQCKVDGTPEIRISWYKEHTKLRSAPAYKMQFKNNVASLVINKVDHSDVGEYSCK 8020
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEE-GENVTFKCAVKGNPS 124
A N +G S+A LV+ R+L P F+ V E G V F+C + G+
Sbjct: 8021 ADNSVGAVASSAVLVI-KERKL--------PPFFARKLKDVHETLGFPVAFECRINGSEP 8071
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
SW KDG ++ A + + L+I + +G Y + N LG A +SA+L
Sbjct: 8072 LQVSWYKDGVLLKDDANLQTSFVHNV-ATLQILQTDQSHIGQYNCSASNPLGTASSSAKL 8130
Score = 81.0 bits (191), Expect = 3e-15
Identities = 54/183 (29%), Positives = 85/183 (46%), Gaps = 13/183 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G V FEC++ G+ + W+ +++D A+ ++S+ A L+I Q G Y C
Sbjct: 8057 GFPVAFECRINGSEPLQVSWYKDGVLLKDDANLQTSFVHNVATLQILQTDQSHIGQYNCS 8116
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
ASN LG A S+A L++ ++ P F P + + GE+ TFKC V G
Sbjct: 8117 ASNPLGTASSSAKLILSE--------HEVPPFFDLKPVSVDLALGESGTFKCHVTGTAPI 8168
Query: 126 WASWDKDGSIITPSA--RITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
+W KD I P ++T+ E + +L++ + D G Y N G+ SA
Sbjct: 8169 KITWAKDNREIRPGGNYKMTLVENTATLTVLKVGK---GDAGQYTCYASNIAGKDSCSAH 8225
Query: 184 LEV 186
L V
Sbjct: 8226 LGV 8228
Score = 80.2 bits (189), Expect = 5e-15
Identities = 55/181 (30%), Positives = 82/181 (45%), Gaps = 9/181 (4%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G V C++ G+ + W+ ++RD + ++S+ D A LKI Q G Y+C
Sbjct: 7116 GLPVTLTCRLNGSAPIQVCWYRDGVLLRDDENLQTSFVDNVATLKILQTDLSHSGQYSCS 7175
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
ASN LG A S+A RL++ + +P F P + V GE+ F+C V G
Sbjct: 7176 ASNPLGTASSSA--------RLTAREPKKSPFFDIKPVSIDVIAGESADFECHVTGAQPM 7227
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
+W KD I P T+ L I +V D G Y N++G+ SA+L
Sbjct: 7228 RITWSKDNKEIRPGGNYTITCVGNTPH-LRILKVGKGDSGQYTCQATNDVGKDMCSAQLS 7286
Query: 186 V 186
V
Sbjct: 7287 V 7287
Score = 80.2 bits (189), Expect = 5e-15
Identities = 52/183 (28%), Positives = 91/183 (49%), Gaps = 12/183 (6%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G++ +FEC VTG + W + IR ++ SY + +A L + +V D G YTC
Sbjct: 9094 GESADFECHVTGTQPIKVSWAKDSREIRSGGKYQISYLENSAHLTVLKVDKGDSGQYTCY 9153
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKC--AVKGNP 123
A N +GK ++C T +L+ R + P+F T ++ VEE E +FK V G+
Sbjct: 9154 AVNEVGK---DSC-----TAQLNIKERLIPPSF-TKRLSETVEETEGNSFKLEGRVAGSQ 9204
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
+W K+ I P++ + K + +L++ + + D G+Y V N+ G A ++
Sbjct: 9205 PITVAWYKNNIEIQPTSNCEITFKNNTL-VLQVRKAGMNDAGLYTCKVSNDAGSALCTSS 9263
Query: 184 LEV 186
+ +
Sbjct: 9264 IVI 9266
Score = 79.8 bits (188), Expect = 7e-15
Identities = 47/179 (26%), Positives = 78/179 (43%), Gaps = 9/179 (5%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
GD+V +CQV G P+ + W+ +R ++ + + + A L +V D G YTC+
Sbjct: 7020 GDSVSLQCQVAGTPEITVSWYKGDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGEYTCK 7079
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A N +G A S + RQ+ P+F + G VT C + G+
Sbjct: 7080 AENSIGTASSKTVFRIQE--------RQLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPI 7131
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
W +DG ++ + + + L+I + + G Y + N LG A +SARL
Sbjct: 7132 QVCWYRDGVLLRDDENLQTSFVDNV-ATLKILQTDLSHSGQYSCSASNPLGTASSSARL 7189
Score = 79.8 bits (188), Expect = 7e-15
Identities = 52/181 (28%), Positives = 87/181 (48%), Gaps = 11/181 (6%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G++ F+C VTG I W IR +++ + + TA L + +V D G YTC
Sbjct: 8153 GESGTFKCHVTGTAPIKITWAKDNREIRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCY 8212
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
ASN GK +A L V R +++ P +++V++ E ++C + G+P
Sbjct: 8213 ASNIAGKDSCSAHLGVQEPPRFI---KKLEP-------SRIVKQDEFTRYECKIGGSPEI 8262
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
W KD + I S++ + + + +LE+ +S+ED G Y N G A +S L+
Sbjct: 8263 KVLWYKDETEIQESSKFRMSFVDSV-AVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLK 8321
Query: 186 V 186
V
Sbjct: 8322 V 8322
Score = 78.6 bits (185), Expect = 2e-14
Identities = 47/180 (26%), Positives = 78/180 (43%), Gaps = 12/180 (6%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G++++ EC+++G+P+ + WF + + + S+ + A L I + +AED G Y CE
Sbjct: 7306 GESIQLECKISGSPEIKVSWFRNDSELHESWKYNMSFINSVALLTINEASAEDSGDYICE 7365
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A N +G A + L V + P F P +G +V +C + G P
Sbjct: 7366 AHNGVGDASCSTALTV-----------KAPPVFTQKPSPVGALKGSDVILQCEISGTPPF 7414
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
W KD + S + + K L I + DVG Y NE+G S ++
Sbjct: 7415 EVVWVKDRKQVRNSKKFKITSK-HFDTSLHILNLEASDVGEYHCKATNEVGSDTCSCSVK 7473
Score = 78.2 bits (184), Expect = 2e-14
Identities = 50/181 (27%), Positives = 81/181 (44%), Gaps = 13/181 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
GD+ +CQ+ G P+ + W+ +R ++ + + A L QV D G Y C+
Sbjct: 8902 GDSASLQCQLAGTPEIGVSWYKGDTKLRPTTTYKMHFRNNVATLVFNQVDINDSGEYICK 8961
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A N +G+ ++ L V + S RQ+ T G V F CA+ G+
Sbjct: 8962 AENSVGEVSASTFLTVQEQKLPPSFSRQLRDVQETV--------GLPVVFDCAISGSEPI 9013
Query: 126 WASWDKDGSII--TPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
SW KDG + +P+ + + + + I + D S+ G Y T N +G A +SAR
Sbjct: 9014 SVSWYKDGKPLKDSPNVQTSFLDNTATLNIFKTDR-SL--AGQYSCTATNPIGSASSSAR 9070
Query: 184 L 184
L
Sbjct: 9071 L 9071
Score = 77.8 bits (183), Expect = 3e-14
Identities = 50/184 (27%), Positives = 76/184 (41%), Gaps = 10/184 (5%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G +F C++ P+ +WF I + + L+I + D G YTC+
Sbjct: 4397 GHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCK 4456
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
ASN G A L V PTF + P + G+ F C V G P
Sbjct: 4457 ASNEYGSVSCTATLTVTEA---------YPPTFLSRPKSLTTFVGKAAKFICTVTGTPVI 4507
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
W KDG+ ++PS + + E ILE+ ++I+D G+Y N+ G A L
Sbjct: 4508 ETIWQKDGAALSPSPNWKISDAEN-KHILELSNLTIQDRGVYSCKASNKFGADICQAELI 4566
Query: 186 VITR 189
+I +
Sbjct: 4567 IIDK 4570
Score = 77.4 bits (182), Expect = 4e-14
Identities = 61/205 (29%), Positives = 91/205 (44%), Gaps = 14/205 (6%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G+ V+ C V G+ I+W I+ S+ GTA L+++ V D G Y C
Sbjct: 9286 EGEYVQLSCHVQGSEPIRIQWLKAGREIKPSDRCSFSFASGTAVLELRDVAKADSGDYVC 9345
Query: 65 EASNCLGK--AKSNACL-----VVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKC 117
+ASN G KS + V T++ + GR F + P + V E TF
Sbjct: 9346 KASNVAGSDTTKSKVTIKDKPAVAPATKKAAVDGRLF---FVSEPQSIRVVEKTTATFIA 9402
Query: 118 AVKGNPSPWASWDK-DGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG 176
V G+P P W K + R+ + +K + + LEI + + D G+YR NE G
Sbjct: 9403 KVGGDPIPNVKWTKGKWRQLNQGGRVFIHQKGDEAK-LEIRDTTKTDSGLYRCVAFNEHG 9461
Query: 177 RAEASARLEVITR--SGKFYGGLRA 199
E++ L+V R K G LRA
Sbjct: 9462 EIESNVNLQVDERKKQEKIEGDLRA 9486
Score = 77.0 bits (181), Expect = 5e-14
Identities = 52/184 (28%), Positives = 79/184 (42%), Gaps = 8/184 (4%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAE-VIRDCADFESSYDDGTARLKIKQVTAEDEGTYT 63
+G T F+ +V G P P+ WFH + ++ D +DGT L I T D G +T
Sbjct: 1470 EGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWT 1529
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
A N G++ + L V + Q+ P F N ++EG + K GNP
Sbjct: 1530 VVAQNRAGRSSISVILTV------EAVEHQVKPMFVEKLKNVNIKEGSQLEMKVRATGNP 1583
Query: 124 SPWASWDKDGSIITPSARITVK-EKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASA 182
+P W K+ II P ++ E + L+ID +D Y T N+ GR
Sbjct: 1584 NPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRC 1643
Query: 183 RLEV 186
++ V
Sbjct: 1644 KVNV 1647
Score = 77.0 bits (181), Expect = 5e-14
Identities = 45/166 (27%), Positives = 77/166 (46%), Gaps = 12/166 (7%)
Query: 11 FECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCL 70
+EC++ G+P+ + W+ I++ + F S+ D A L++ ++ ED G YTCEA N
Sbjct: 8252 YECKIGGSPEIKVLWYKDETEIQESSKFRMSFVDSVAVLEMHNLSVEDSGDYTCEAHNAA 8311
Query: 71 GKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWD 130
G A S+ L ++ P P F P +G +V +C ++G P SW
Sbjct: 8312 GSASSSTSL------KVKEP-----PIFRKKPHPIETLKGADVHLECELQGTPPFHVSWY 8360
Query: 131 KDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG 176
KD + + + E + + I V D+G Y+ N++G
Sbjct: 8361 KDKRELRSGKKYKIM-SENFLTSIHILNVDAADIGEYQCKATNDVG 8405
Score = 76.6 bits (180), Expect = 6e-14
Identities = 54/182 (29%), Positives = 85/182 (46%), Gaps = 13/182 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G++ +FEC VTG I W + IR ++ + T L+I +V D G YTC+
Sbjct: 7212 GESADFECHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYTCQ 7271
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYT-YPFNKVVEEGENVTFKCAVKGNPS 124
A+N +GK +A L V + P F +KV ++GE++ +C + G+P
Sbjct: 7272 ATNDVGKDMCSAQLSV-----------KEPPKFVKKLEASKVAKQGESIQLECKISGSPE 7320
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
SW ++ S + S + + + +L I+E S ED G Y N +G A S L
Sbjct: 7321 IKVSWFRNDSELHESWKYNMSFINSV-ALLTINEASAEDSGDYICEAHNGVGDASCSTAL 7379
Query: 185 EV 186
V
Sbjct: 7380 TV 7381
Score = 74.1 bits (174), Expect = 3e-13
Identities = 51/180 (28%), Positives = 79/180 (43%), Gaps = 12/180 (6%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G + FECQ+TG P + W+ I S+ DG A +I E+ GTY C
Sbjct: 5802 NGQSTTFECQITGTPKIRVSWYLDGNEITAIQKHGISFIDGLATFQISGARVENSGTYVC 5861
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
EA N G A +C + + + R++ P +VV+ + V +C V G P
Sbjct: 5862 EARNDAGTA---SCSIELKVKEPPTFIRELKPV-------EVVKYSD-VELECEVTGTPP 5910
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
+W K+ I S + T+ ++ + L I + D G Y+ V NE G S R+
Sbjct: 5911 FEVTWLKNNREIRSSKKYTLTDRVSVFN-LHITKCDPSDTGEYQCIVSNEGGSCSCSTRV 5969
Score = 73.3 bits (172), Expect = 6e-13
Identities = 52/184 (28%), Positives = 79/184 (42%), Gaps = 6/184 (3%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G F ++G P P I W+ +++ + +D L + + ED YTCE
Sbjct: 3253 GKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCE 3312
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQM---APTFYTYPFNKVVEEGENVTFKCAVKGN 122
A N G A ++A L V + SP ++M P T + V EG+ F+C V G
Sbjct: 3313 AKNDYGVATTSASLSV-EVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGT 3371
Query: 123 PSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASA 182
SW I PS + + E+ + LEI E ED G Y N +G+ ++A
Sbjct: 3372 DLK-VSWYSKDKKIKPSRFFRMTQFEDTYQ-LEIAEAYPEDEGTYTFVASNAVGQVSSTA 3429
Query: 183 RLEV 186
L +
Sbjct: 3430 NLSL 3433
Score = 73.3 bits (172), Expect = 6e-13
Identities = 51/186 (27%), Positives = 89/186 (47%), Gaps = 13/186 (6%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G V F+C ++G+ + W+ + ++D + ++S+ D TA L I + G Y+C
Sbjct: 8998 GLPVVFDCAISGSEPISVSWYKDGKPLKDSPNVQTSFLDNTATLNIFKTDRSLAGQYSCT 9057
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A+N +G A S+A L++ + ++AP + VV GE+ F+C V G
Sbjct: 9058 ATNPIGSASSSARLILTEGKNPPFFDIRLAPV------DAVV--GESADFECHVTGTQPI 9109
Query: 126 WASWDKDGSIITPSAR--ITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
SW KD I + I+ E + +L++D+ D G Y NE+G+ +A+
Sbjct: 9110 KVSWAKDSREIRSGGKYQISYLENSAHLTVLKVDK---GDSGQYTCYAVNEVGKDSCTAQ 9166
Query: 184 LEVITR 189
L + R
Sbjct: 9167 LNIKER 9172
Score = 72.5 bits (170), Expect = 1e-12
Identities = 51/179 (28%), Positives = 76/179 (42%), Gaps = 12/179 (6%)
Query: 8 TVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEAS 67
T +C++ G+ + WF + I + ++ +GTA L+I +V D G +TC A+
Sbjct: 5056 TCRLDCKIAGSLPMRVSWFKDGKEIAASDRYRIAFVEGTASLEIIRVDMNDAGNFTCRAT 5115
Query: 68 NCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWA 127
N +G S+ L+V Q P+F T P +K V G V K +G+
Sbjct: 5116 NSVGSKDSSGALIV-----------QEPPSFVTKPGSKDVLPGSAVCLKSTFQGSTPLTI 5164
Query: 128 SWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W K + + KE + LE+ V D G Y V N G E SA L V
Sbjct: 5165 RWFKGNKELVSGGSCYI-TKEALESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFV 5222
Score = 72.1 bits (169), Expect = 1e-12
Identities = 54/186 (29%), Positives = 79/186 (42%), Gaps = 12/186 (6%)
Query: 1 MLSCDGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEG 60
M S G ++ EC V G+ I+WF + I ++ S+ D TA L+I Q+ D G
Sbjct: 5611 MDSIKGSFIDLECIVAGSHPISIQWFKDDQEISASEKYKFSFHDNTAFLEISQLEGTDSG 5670
Query: 61 TYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVK 120
TYTC A+N G + + L V + P F P ++ V V K V
Sbjct: 5671 TYTCSATNKAGHNQCSGHLTV-----------KEPPYFVEKPQSQDVNPNTRVQLKALVG 5719
Query: 121 GNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEA 180
G W KD + A +V K++ LE+ D G Y + N++G A +
Sbjct: 5720 GTAPMTIKWFKDNKELHSGAARSV-WKDDTSTSLELFAAKATDSGTYICQLSNDVGTATS 5778
Query: 181 SARLEV 186
A L V
Sbjct: 5779 KATLFV 5784
Score = 72.1 bits (169), Expect = 1e-12
Identities = 48/180 (26%), Positives = 78/180 (43%), Gaps = 12/180 (6%)
Query: 11 FECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCL 70
F+ V G+P I W +++ + + S+ D A L+I+ V G YTC+A N
Sbjct: 5994 FQSTVAGSPPISITWLKDDQILDEDDNVYISFVDSVATLQIRSVDNGHSGRYTCQAKNES 6053
Query: 71 GKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWD 130
G + A L+V ++ + + V E + +T +C V G P W
Sbjct: 6054 GVERCYAFLLVQEPAQIVEKAKSVD-----------VTEKDPMTLECVVAGTPELKVKWL 6102
Query: 131 KDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVITRS 190
KDG I PS ++ + + I V +D G Y VEN+ G + A L V+ ++
Sbjct: 6103 KDGKQIVPSRYFSMSFENNVAS-FRIQSVMKQDSGQYTFKVENDFGSSSCDAYLRVLDQN 6161
Score = 72.1 bits (169), Expect = 1e-12
Identities = 51/183 (27%), Positives = 77/183 (42%), Gaps = 14/183 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G V F V G P + WF + + S +D A L++ V G YTC
Sbjct: 8716 GTNVTFTSIVKGTPPFSVSWFKGSSELVPGDRCNVSLEDSVAELELFDVDTSQSGEYTCI 8775
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKV-VEEGENVTFKCAVKGNPS 124
SN GKA L + AP + N +E+G+ + + G P
Sbjct: 8776 VSNEAGKASCTTHLYI------------KAPAKFVKRLNDYSIEKGKPLILEGTFTGTPP 8823
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
+W K+G +TPS R + E+ ILEI ++ED G Y +EN G+ SA++
Sbjct: 8824 ISVTWKKNGINVTPSQRCNITTTEK-SAILEIPSSTVEDAGQYNCYIENASGKDSCSAQI 8882
Query: 185 EVI 187
++
Sbjct: 8883 LIL 8885
Score = 71.7 bits (168), Expect = 2e-12
Identities = 51/180 (28%), Positives = 83/180 (46%), Gaps = 14/180 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
GD + C+VTG P I WF I++ + S+ + TA L++ V ED G Y CE
Sbjct: 5241 GDATQLACKVTGTPPIKITWFANDREIKESSKHRMSFVESTAVLRLTDVGIEDSGEYMCE 5300
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKV-VEEGENVTFKCAVKGNPS 124
A N G ++ ++V SP ++T F + V + +V V G P
Sbjct: 5301 AQNEAGSDHCSSIVIV-----KESP-------YFTKEFKPIEVLKEYDVMLLAEVAGTPP 5348
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
+W KD +I+ + ++ ++ L+I + D G Y+ V NE+G + SAR+
Sbjct: 5349 FEITWFKDNTILRSGRKYKTFIQDHLVS-LQILKFVAADAGEYQCRVTNEVGSSICSARV 5407
Score = 70.5 bits (165), Expect = 4e-12
Identities = 50/181 (27%), Positives = 79/181 (43%), Gaps = 11/181 (6%)
Query: 7 DTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEA 66
D + EC V G P+ ++W + I F S+++ A +I+ V +D G YT +
Sbjct: 6083 DPMTLECVVAGTPELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSGQYTFKV 6142
Query: 67 SNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEE-GENVTFKCAVKGNPSP 125
N G + +A L V Q P +T K+ + G ++ +C V G+
Sbjct: 6143 ENDFGSSSCDAYLRVLD---------QNIPPSFTKKLTKMDKVLGSSIHMECKVSGSLPI 6193
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
A W KDG I+ SA+ + E + LE++ + +ED Y V N G S L
Sbjct: 6194 SAQWFKDGKEISTSAKYRLVCHERSVS-LEVNNLELEDTANYTCKVSNVAGDDACSGILT 6252
Query: 186 V 186
V
Sbjct: 6253 V 6253
Score = 70.1 bits (164), Expect = 6e-12
Identities = 46/178 (25%), Positives = 80/178 (44%), Gaps = 11/178 (6%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
V ECQV + + W + + D++ ++D A L+I +D GTY C ASN
Sbjct: 4588 VHLECQVDEDRKVTVTWSKDGQKLPPGKDYKICFEDKIATLEIPLAKLKDSGTYVCTASN 4647
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
+A S++C R S +++ P++ P GE+ C +KG+P +
Sbjct: 4648 ---EAGSSSCSATVTVREPPSFVKKVDPSYLMLP-------GESARLHCKLKGSPVIQVT 4697
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W K+ ++ S + + IL+I +V +ED G Y N++G S + +
Sbjct: 4698 WFKNNKELSESNTVRMYFVNS-EAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVI 4754
Score = 70.1 bits (164), Expect = 6e-12
Identities = 49/181 (27%), Positives = 76/181 (41%), Gaps = 12/181 (6%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G +V EC+V+G+ + WF I +SS+ + L + + D G YTC
Sbjct: 7682 GASVVLECRVSGSAPISVGWFQDGNEIVSGPKCQSSFSENVCTLNLSLLEPSDTGIYTCV 7741
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A+N G + +A L V Q P+F P + V G ++TF ++G P
Sbjct: 7742 AANVAGSDECSAVLTV-----------QEPPSFEQTPDSVEVLPGMSLTFTSVIRGTPPF 7790
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
W K + P + E+ + LE+ EV + G Y V N+ G A + L
Sbjct: 7791 KVKWFKGSRELVPGESCNI-SLEDFVTELELFEVQPLESGDYSCLVTNDAGSASCTTHLF 7849
Query: 186 V 186
V
Sbjct: 7850 V 7850
Score = 68.9 bits (161), Expect = 1e-11
Identities = 48/186 (25%), Positives = 79/186 (42%), Gaps = 13/186 (6%)
Query: 6 GDTVEFECQVTGNPDPDIRWFH-YAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
G V+ + + G + WF E++R+ + SY + A L+ +V + G YTC
Sbjct: 8433 GKEVQLQTTIEGAEPISVVWFKDKGEIVRESDNIWISYSENIATLQFSRVEPANAGKYTC 8492
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
+ N G + A L V T P + V G+ T +C V G P
Sbjct: 8493 QIKNDAGMQECFATLSVLEPA-----------TIVEKPESIKVTTGDTCTLECTVAGTPE 8541
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
W KDG +T + + ++ L+I V+ D G+Y V+N +G+ +A L
Sbjct: 8542 LSTKWFKDGKELTSDNKYKISFFNKVSG-LKIINVAPSDSGVYSFEVQNPVGKDSCTASL 8600
Query: 185 EVITRS 190
+V R+
Sbjct: 8601 QVSDRT 8606
Score = 68.5 bits (160), Expect = 2e-11
Identities = 53/196 (27%), Positives = 76/196 (38%), Gaps = 14/196 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
GD V G P P I+WF ++ AD++ +D L I EDEG YTC
Sbjct: 3517 GDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCM 3576
Query: 66 ASNCLGKAKSNACLVVYH--------------TRRLSSPGRQMAPTFYTYPFNKVVEEGE 111
ASN GK +A L + + L G P F +G
Sbjct: 3577 ASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGL 3636
Query: 112 NVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITV 171
F+ V G P+P +W K+ + S T+ +++ ED G+Y
Sbjct: 3637 PAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKA 3696
Query: 172 ENELGRAEASARLEVI 187
EN LG + +A L V+
Sbjct: 3697 ENMLGESTCAAELLVL 3712
Score = 66.1 bits (154), Expect = 9e-11
Identities = 47/189 (24%), Positives = 74/189 (39%), Gaps = 12/189 (6%)
Query: 1 MLSCDGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEG 60
+++ G TV + V G+ + W EVIR+ + S+ +G A L I V G
Sbjct: 4860 LIALGGQTVTLQAAVRGSEPISVTWMKGQEVIREDGKIKMSFSNGVAVLIIPDVQISFGG 4919
Query: 61 TYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVK 120
YTC A N G S L+V ++ + V G+ T + V
Sbjct: 4920 KYTCLAENEAGSQTSVGELIVKEPAKIIERAELIQ-----------VTAGDPATLEYTVA 4968
Query: 121 GNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEA 180
G P W KDG + S + + K + + L+ + D G Y + NE+G +
Sbjct: 4969 GTPELKPKWYKDGRPLVASKKYRISFKNNVAQ-LKFYSAELHDSGQYTFEISNEVGSSSC 5027
Query: 181 SARLEVITR 189
V+ R
Sbjct: 5028 ETTFTVLDR 5036
Score = 66.1 bits (154), Expect = 9e-11
Identities = 48/178 (26%), Positives = 77/178 (43%), Gaps = 11/178 (6%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
V+ + V G I+WF + + A DD + L++ A D GTY C+ SN
Sbjct: 5712 VQLKALVGGTAPMTIKWFKDNKELHSGAARSVWKDDTSTSLELFAAKATDSGTYICQLSN 5771
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
+G A S A L V + ++ +P V+ G++ TF+C + G P S
Sbjct: 5772 DVGTATSKATLFVKEPPQFI---KKPSPVL-------VLRNGQSTTFECQITGTPKIRVS 5821
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W DG+ IT + + + + +I +E+ G Y N+ G A S L+V
Sbjct: 5822 WYLDGNEITAIQKHGISFIDG-LATFQISGARVENSGTYVCEARNDAGTASCSIELKV 5878
Score = 66.1 bits (154), Expect = 9e-11
Identities = 42/173 (24%), Positives = 76/173 (43%), Gaps = 16/173 (9%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
GD+ EC++ G+P+ + WF + + ++ D A +++ ++ ED G + CE
Sbjct: 6365 GDSSRLECKIAGSPEIRVVWFRNEHELPASDKYRMTFIDSVAVIQMNNLSTEDSGDFICE 6424
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGEN--VTFKCAVKGNP 123
A N G + ++V + P F ++P +VE +N V+ +C + G P
Sbjct: 6425 AQNPAGSTSCSTKVIV-----------KEPPVFSSFP--PIVETLKNAEVSLECELSGTP 6471
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG 176
W KD + S + + K + I V D+G Y +NE+G
Sbjct: 6472 PFEVVWYKDKRQLRSSKKYKIASK-NFHTSIHILNVDTSDIGEYHCKAQNEVG 6523
Score = 66.1 bits (154), Expect = 9e-11
Identities = 46/188 (24%), Positives = 81/188 (43%), Gaps = 17/188 (9%)
Query: 6 GDTVEFECQVTGNPDPDIRWF-HYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
G+ E + + G ++W EVIR+ + ++ + A L+ + + G Y C
Sbjct: 6551 GEPAELQASIEGAQPIFVQWLKEKEEVIRESENIRITFVENVATLQFAKAEPANAGKYIC 6610
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
+ N G ++ A L+V + M T GE T +C V G P
Sbjct: 6611 QIKNDGGMEENMATLMVLEPAVIVEKAGPMTVTV-----------GETCTLECKVAGTPE 6659
Query: 125 PWASWDKDGSIITPSA--RITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASA 182
W KDG ++T S + + K +RIL ++ +D G Y V+N +G++ +A
Sbjct: 6660 LSVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVER---QDAGTYTFQVQNNVGKSSCTA 6716
Query: 183 RLEVITRS 190
++V R+
Sbjct: 6717 VVDVSDRA 6724
Score = 65.7 bits (153), Expect = 1e-10
Identities = 49/181 (27%), Positives = 75/181 (41%), Gaps = 9/181 (4%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
GDT EC V G P+ +WF + + ++ S+ + + LKI V D G Y+ E
Sbjct: 8527 GDTCTLECTVAGTPELSTKWFKDGKELTSDNKYKISFFNKVSGLKIINVAPSDSGVYSFE 8586
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
N +GK ++C T L R + P+F G +V +C V G+P
Sbjct: 8587 VQNPVGK---DSC-----TASLQVSDRTVPPSFTRKLKETNGLSGSSVVMECKVYGSPPI 8638
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
SW +G+ I+ + + L ++ + D G Y N G E SA L
Sbjct: 8639 SVSWFHEGNEISSGRKYQTTLTDNTC-ALTVNMLEESDSGDYTCIATNMAGSDECSAPLT 8697
Query: 186 V 186
V
Sbjct: 8698 V 8698
Score = 64.9 bits (151), Expect = 2e-10
Identities = 27/77 (35%), Positives = 42/77 (54%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G++V EC ++G P P + W+ I DF+ ++ G ARL I++ AED G +TC
Sbjct: 956 EGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTC 1015
Query: 65 EASNCLGKAKSNACLVV 81
A N G ++ L V
Sbjct: 1016 SAVNEAGTVSTSCYLAV 1032
Score = 64.1 bits (149), Expect = 4e-10
Identities = 46/181 (25%), Positives = 76/181 (41%), Gaps = 12/181 (6%)
Query: 2 LSCDGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGT 61
L G++ C++ G+P + WF + + + + + A L I V ED G+
Sbjct: 4675 LMLPGESARLHCKLKGSPVIQVTWFKNNKELSESNTVRMYFVNSEAILDITDVKVEDSGS 4734
Query: 62 YTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKG 121
Y+CEA N +G + +V+ + P+F + G N +C V G
Sbjct: 4735 YSCEAVNDVGSDSCSTEIVI-----------KEPPSFIKTLEPADIVRGTNALLQCEVSG 4783
Query: 122 NPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEAS 181
SW KD I S + + ++ ++ LEI + DVG Y V NE+G+
Sbjct: 4784 TGPFEISWFKDKKQIRSSKKYRLFSQKSLV-CLEIFSFNSADVGEYECVVANEVGKCGCM 4842
Query: 182 A 182
A
Sbjct: 4843 A 4843
Score = 64.1 bits (149), Expect = 4e-10
Identities = 44/182 (24%), Positives = 80/182 (43%), Gaps = 9/182 (4%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G++ + E +V G+ + W+ I+ ++ E ++ + T L++++ D G YTC
Sbjct: 9190 EGNSFKLEGRVAGSQPITVAWYKNNIEIQPTSNCEITFKNNTLVLQVRKAGMNDAGLYTC 9249
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
+ SN G A + +V+ ++ P F + V EGE V C V+G+
Sbjct: 9250 KVSNDAGSALCTSSIVIKEPKK--------PPVFDQHLTPVTVSEGEYVQLSCHVQGSEP 9301
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
W K G I PS R + +LE+ +V+ D G Y N G +++
Sbjct: 9302 IRIQWLKAGREIKPSDRCSFSFASG-TAVLELRDVAKADSGDYVCKASNVAGSDTTKSKV 9360
Query: 185 EV 186
+
Sbjct: 9361 TI 9362
Score = 63.7 bits (148), Expect = 5e-10
Identities = 47/185 (25%), Positives = 75/185 (40%), Gaps = 13/185 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFH-YAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
GD VE V G + W EVIR+ + S+ D A L++ A + G Y C
Sbjct: 7492 GDAVELRAIVEGFQPISVVWLKDRGEVIRESENTRISFIDNIATLQLGSPEASNSGKYIC 7551
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
+ N G + +A L V R+ M V G +C V G P
Sbjct: 7552 QIKNDAGMRECSAVLTVLEPARIIEKPEPM-----------TVTTGNPFALECVVTGTPE 7600
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
A W KDG ++ ++ + ++ L+I + D G+Y V+N +G++ + +
Sbjct: 7601 LSAKWFKDGRELSADSKHHITFINKVAS-LKIPCAEMSDKGLYSFEVKNSVGKSNCTVSV 7659
Query: 185 EVITR 189
V R
Sbjct: 7660 HVSDR 7664
Score = 63.3 bits (147), Expect = 6e-10
Identities = 41/185 (22%), Positives = 80/185 (43%), Gaps = 12/185 (6%)
Query: 3 SCDGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTY 62
S G T F+ + G+ + W ++ I + + ++++ A L + + + +G Y
Sbjct: 5424 SLRGGTAAFQATLKGSLPITVTWLKDSDEITEDDNIRMTFENNVASLYLSGIEVKHDGKY 5483
Query: 63 TCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGN 122
C+A N G + +A L V ++ + V +G+ T + G
Sbjct: 5484 VCQAKNDAGIQRCSALLSVKEPATITEEAVSID-----------VTQGDPATLQVKFSGT 5532
Query: 123 PSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASA 182
A W KDG +T ++ + + + IL+I +D G Y V+N++GR+ A
Sbjct: 5533 KEITAKWFKDGQELTLGSKYKISVTDTV-SILKIISTEKKDSGEYTFEVQNDVGRSSCKA 5591
Query: 183 RLEVI 187
R+ V+
Sbjct: 5592 RINVL 5596
Score = 63.3 bits (147), Expect = 6e-10
Identities = 48/181 (26%), Positives = 72/181 (39%), Gaps = 9/181 (4%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+ EC VTG P+ +WF + + ++ + A LKI D+G Y+ E
Sbjct: 7586 GNPFALECVVTGTPELSAKWFKDGRELSADSKHHITFINKVASLKIPCAEMSDKGLYSFE 7645
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
N +GK+ C V H R + P+F + G +V +C V G+
Sbjct: 7646 VKNSVGKSN---CTVSVHV-----SDRIVPPSFIRKLKDVNAILGASVVLECRVSGSAPI 7697
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
W +DG+ I + E + L + + D GIY N G E SA L
Sbjct: 7698 SVGWFQDGNEIVSGPKCQSSFSENVC-TLNLSLLEPSDTGIYTCVAANVAGSDECSAVLT 7756
Query: 186 V 186
V
Sbjct: 7757 V 7757
Score = 62.9 bits (146), Expect = 8e-10
Identities = 37/102 (36%), Positives = 46/102 (45%), Gaps = 1/102 (0%)
Query: 84 TRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARIT 143
T + PG AP F T P + + EG +V F C V GNP P W K G +T R
Sbjct: 1070 TEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYK 1129
Query: 144 VKEKEEIMRI-LEIDEVSIEDVGIYRITVENELGRAEASARL 184
V ++ L I +D G Y I V N+ G ASA L
Sbjct: 1130 VSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1171
Score = 62.9 bits (146), Expect = 8e-10
Identities = 36/96 (37%), Positives = 51/96 (53%), Gaps = 1/96 (1%)
Query: 96 PTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILE 155
PT + +V EGE ++ + P P SW KDG + S R+T+K + I LE
Sbjct: 15314 PTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKN-DHISAHLE 15372
Query: 156 IDEVSIEDVGIYRITVENELGRAEASARLEVITRSG 191
+ + D GIY IT+EN+LG A AS ++VI G
Sbjct: 15373 VPKSVRADAGIYTITLENKLGSATASINVKVIGLPG 15408
Score = 62.5 bits (145), Expect = 1e-09
Identities = 43/181 (23%), Positives = 77/181 (42%), Gaps = 9/181 (4%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+T EC+V G P+ + W+ +++ + S+ + + L+I V +D GTYT +
Sbjct: 6645 GETCTLECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVERQDAGTYTFQ 6704
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
N +GK+ A + V R + P+F N G + +C V G+
Sbjct: 6705 VQNNVGKSSCTAVVDV--------SDRAVPPSFTRRLKNTGGVLGASCILECKVAGSSPI 6756
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
+W + + I A+ + + L+++ + D+G Y N G E A L
Sbjct: 6757 SVAWFHEKTKIVSGAKYQTTFSDNVC-TLQLNSLDSSDMGNYTCVAANVAGSDECRAVLT 6815
Query: 186 V 186
V
Sbjct: 6816 V 6816
Score = 61.7 bits (143), Expect = 2e-09
Identities = 49/182 (26%), Positives = 76/182 (41%), Gaps = 12/182 (6%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G ++ F + G P ++WF + + S +D L++ +V + G Y+C
Sbjct: 7775 GMSLTFTSVIRGTPPFKVKWFKGSRELVPGESCNISLEDFVTELELFEVQPLESGDYSCL 7834
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
+N G A L V P TF + VE G + + G P
Sbjct: 7835 VTNDAGSASCTTHLFV------KEPA-----TFVKRLADFSVETGSPIVLEATYTGTPPI 7883
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
SW KD +I+ S R ++ E+ ILEI E +IED Y +ENE G+ A +
Sbjct: 7884 SVSWIKDEYLISQSERCSITMTEK-STILEILESTIEDYAQYSCLIENEAGQDICEALVS 7942
Query: 186 VI 187
V+
Sbjct: 7943 VL 7944
Score = 60.5 bits (140), Expect = 5e-09
Identities = 50/186 (26%), Positives = 76/186 (40%), Gaps = 13/186 (6%)
Query: 2 LSCDGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAED-EG 60
+S +GD V +T + + W+ +++ F+ D T L I +V ED +G
Sbjct: 4299 VSEEGDIVHLTTSITNAKE--VNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQG 4356
Query: 61 TYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVK 120
Y CEA N GK ++A L V ++ AP V G F C ++
Sbjct: 4357 EYVCEALNDSGKTATSAKLTVV---------KRAAPVIKRKIEPLEVALGHLAKFTCEIQ 4407
Query: 121 GNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEA 180
P+ W K G I S + +++ + I LEI + D G Y NE G
Sbjct: 4408 SAPNVRFQWFKAGREIYESDKCSIRSSKYISS-LEILRTQVVDCGEYTCKASNEYGSVSC 4466
Query: 181 SARLEV 186
+A L V
Sbjct: 4467 TATLTV 4472
Score = 60.1 bits (139), Expect = 6e-09
Identities = 46/181 (25%), Positives = 76/181 (41%), Gaps = 12/181 (6%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G +F C VTG P + W + +++ S + L++ +T +D G Y+C+
Sbjct: 4492 GKAAKFICTVTGTPVIETIWQKDGAALSPSPNWKISDAENKHILELSNLTIQDRGVYSCK 4551
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
ASN G A L++ +++ P NK V +C V +
Sbjct: 4552 ASNKFGADICQAELIIIDKPHFI---KELEPV--QSAINK------KVHLECQVDEDRKV 4600
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
+W KDG + P + +++I LEI ++D G Y T NE G + SA +
Sbjct: 4601 TVTWSKDGQKLPPGKDYKICFEDKI-ATLEIPLAKLKDSGTYVCTASNEAGSSSCSATVT 4659
Query: 186 V 186
V
Sbjct: 4660 V 4660
Score = 59.7 bits (138), Expect = 8e-09
Identities = 48/182 (26%), Positives = 70/182 (38%), Gaps = 12/182 (6%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G V F + G P + WF A + ++D A L++ + G YTC
Sbjct: 6834 GKNVTFTSVIRGTPPFKVNWFRGARELVKGDRCNIYFEDTVAELELFNIDISQSGEYTCV 6893
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
SN G+A L V P F + VE G+++ + G
Sbjct: 6894 VSNNAGQASCTTRLFV------KEPA-----AFLKRLSDHSVEPGKSIILESTYTGTLPI 6942
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
+W KDG IT S + + E+ ILEI + D G Y +ENE GR A +
Sbjct: 6943 SVTWKKDGFNITTSEKCNIVTTEKTC-ILEILNSTKRDAGQYSCEIENEAGRDVCGALVS 7001
Query: 186 VI 187
+
Sbjct: 7002 TL 7003
Score = 58.4 bits (135), Expect = 2e-08
Identities = 45/194 (23%), Positives = 76/194 (39%), Gaps = 13/194 (6%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G ++ EC+V+G+ +WF + I A + + + L++ + ED YTC+
Sbjct: 6178 GSSIHMECKVSGSLPISAQWFKDGKEISTSAKYRLVCHERSVSLEVNNLELEDTANYTCK 6237
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
SN G + L V + P+F P + V FK +KG P
Sbjct: 6238 VSNVAGDDACSGILTV-----------KEPPSFLVKPGRQQAIPDSTVEFKAILKGTPPF 6286
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
W KD + + + E L + V G Y V N++G +++ +
Sbjct: 6287 KIKWFKDDVELVSGPKCFI-GLEGSTSFLNLYSVDASKTGQYTCHVTNDVG-SDSCTTML 6344
Query: 186 VITRSGKFYGGLRA 199
++T KF L A
Sbjct: 6345 LVTEPPKFVKKLEA 6358
Score = 58.4 bits (135), Expect = 2e-08
Identities = 30/85 (35%), Positives = 46/85 (54%), Gaps = 1/85 (1%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
V+ G NV V G P P SW KDG+++ P+ I + + + LE+ V+ +D G
Sbjct: 20234 VKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLC-TLELFSVNRKDSGD 20292
Query: 167 YRITVENELGRAEASARLEVITRSG 191
Y IT EN G A+ +L+V+ + G
Sbjct: 20293 YTITAENSSGSKSATIKLKVLDKPG 20317
Score = 57.2 bits (132), Expect = 4e-08
Identities = 47/181 (25%), Positives = 72/181 (39%), Gaps = 12/181 (6%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G +C+V+G +I WF + IR + L+I + D G Y C
Sbjct: 4772 GTNALLQCEVSGTGPFEISWFKDKKQIRSSKKYRLFSQKSLVCLEIFSFNSADVGEYECV 4831
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
+N +GK C+ T L P PTF + + G+ VT + AV+G+
Sbjct: 4832 VANEVGKC---GCMA---THLLKEP-----PTFVKKVDDLIALGGQTVTLQAAVRGSEPI 4880
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
+W K +I +I + + +L I +V I G Y ENE G + L
Sbjct: 4881 SVTWMKGQEVIREDGKIKMSFSNGV-AVLIIPDVQISFGGKYTCLAENEAGSQTSVGELI 4939
Query: 186 V 186
V
Sbjct: 4940 V 4940
Score = 55.6 bits (128), Expect = 1e-07
Identities = 42/182 (23%), Positives = 72/182 (39%), Gaps = 14/182 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G + E TG P + W + + + +A L+I T ED G Y C
Sbjct: 8809 GKPLILEGTFTGTPPISVTWKKNGINVTPSQRCNITTTEKSAILEIPSSTVEDAGQYNCY 8868
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKV-VEEGENVTFKCAVKGNPS 124
N GK +A +++ + P ++ V V G++ + +C + G P
Sbjct: 8869 IENASGKDSCSAQILI------------LEPPYFVKQLEPVKVSVGDSASLQCQLAGTPE 8916
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
SW K + + P+ + + + ++ ++V I D G Y EN +G AS L
Sbjct: 8917 IGVSWYKGDTKLRPTTTYKMHFRNNVATLV-FNQVDINDSGEYICKAENSVGEVSASTFL 8975
Query: 185 EV 186
V
Sbjct: 8976 TV 8977
Score = 55.2 bits (127), Expect = 2e-07
Identities = 45/183 (24%), Positives = 74/183 (40%), Gaps = 13/183 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G V EC++ G P + W+ +R ++ ++ + I V A D G Y C+
Sbjct: 8340 GADVHLECELQGTPPFHVSWYKDKRELRSGKKYKIMSENFLTSIHILNVDAADIGEYQCK 8399
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A+N +G S+ C + S + P F + G+ V + ++G
Sbjct: 8400 ATNDVG---SDTC--------VGSIALKAPPRFVKKLSDISTVVGKEVQLQTTIEGAEPI 8448
Query: 126 WASWDKD-GSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
W KD G I+ S I + E I L+ V + G Y ++N+ G E A L
Sbjct: 8449 SVVWFKDKGEIVRESDNIWISYSENI-ATLQFSRVEPANAGKYTCQIKNDAGMQECFATL 8507
Query: 185 EVI 187
V+
Sbjct: 8508 SVL 8510
Score = 54.0 bits (124), Expect = 4e-07
Identities = 44/183 (24%), Positives = 81/183 (44%), Gaps = 21/183 (11%)
Query: 7 DTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEA 66
DT++ C+V+ P ++ W+ E I + +E + L I+ ED G Y C
Sbjct: 13405 DTIKLVCEVS-KPGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQNAHLEDAGNYNCR- 13462
Query: 67 SNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPW 126
L ++++ + V+ ++A F + P N + EGE F C++ P
Sbjct: 13463 ---LPSSRTDGKVKVH----------ELAAEFISKPQNLEILEGEKAEFVCSISKESFP- 13508
Query: 127 ASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W +D + + V + R+L + + +++D+G Y + V G A A+A L V
Sbjct: 13509 VQWKRDDKTLESGDKYDVIADGK-KRVLVVKDATLQDMGTYVVMV----GAARAAAHLTV 13563
Query: 187 ITR 189
I +
Sbjct: 13564 IEK 13566
Score = 53.6 bits (123), Expect = 5e-07
Identities = 31/87 (35%), Positives = 44/87 (50%), Gaps = 1/87 (1%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSY-DDGTARLKIKQVTAEDEGTYT 63
+G V F C+++G P P I W+ + I+ ++ + DG A L+I V EDEG YT
Sbjct: 1304 EGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYT 1363
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSP 90
ASN G A + L V L +P
Sbjct: 1364 AFASNIKGNAICSGKLYVEPAAPLGAP 1390
Score = 53.6 bits (123), Expect = 5e-07
Identities = 44/185 (23%), Positives = 74/185 (40%), Gaps = 14/185 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G + E TG P + W +I + + + L+I + T ED Y+C
Sbjct: 7868 GSPIVLEATYTGTPPISVSWIKDEYLISQSERCSITMTEKSTILEILESTIEDYAQYSCL 7927
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKV-VEEGENVTFKCAVKGNPS 124
N G+ A + V + P ++ P V GE T +C V G P
Sbjct: 7928 IENEAGQDICEALVSV------------LEPPYFIEPLEHVEAVIGEPATLQCKVDGTPE 7975
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
SW K+ + + + ++ K + ++ I++V DVG Y +N +G +SA L
Sbjct: 7976 IRISWYKEHTKLRSAPAYKMQFKNNVASLV-INKVDHSDVGEYSCKADNSVGAVASSAVL 8034
Query: 185 EVITR 189
+ R
Sbjct: 8035 VIKER 8039
Score = 53.6 bits (123), Expect = 5e-07
Identities = 31/98 (31%), Positives = 49/98 (50%), Gaps = 2/98 (2%)
Query: 102 PFNKV-VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVS 160
PFN ++ GE++ + V G P P SW KDG + + R+ V E+ +L I E +
Sbjct: 25244 PFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNV-EETATSTVLHIKEGN 25302
Query: 161 IEDVGIYRITVENELGRAEASARLEVITRSGKFYGGLR 198
+D G Y +T N G A + + V+ + G G +R
Sbjct: 25303 KDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGPVR 25340
Score = 53.2 bits (122), Expect = 7e-07
Identities = 46/173 (26%), Positives = 70/173 (40%), Gaps = 16/173 (9%)
Query: 6 GDTVEFECQVTGNPDPDIRWF-HYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
G F +V G PDP+ W+ + ++ R + +D L I+ VTAED +
Sbjct: 2092 GSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMV 2151
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVV--EEGENVTFKCAVKGN 122
+A N G+ S+A L+V + ++ +T VV E+ TF+C
Sbjct: 2152 KAINIAGETSSHAFLLVQAKQLIT----------FTQELQDVVAKEKDTMATFECET-SE 2200
Query: 123 PSPWASWDKDGSII--TPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVEN 173
P W KDG + R+ K + IL ID ED + EN
Sbjct: 2201 PFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVEDEN 2253
Score = 53.2 bits (122), Expect = 7e-07
Identities = 32/99 (32%), Positives = 42/99 (42%), Gaps = 1/99 (1%)
Query: 106 VVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVG 165
VV+ G V F ++G P P A W DGS I TV E + +L I D G
Sbjct: 18448 VVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTV-ETDNFSSVLTIKNCLRRDTG 18506
Query: 166 IYRITVENELGRAEASARLEVITRSGKFYGGLRAYSASP 204
Y+ITV N G + L V+ G G + +P
Sbjct: 18507 EYQITVSNAAGSKTVAVHLTVLDVPGPPTGPINILDVTP 18545
Score = 52.8 bits (121), Expect = 9e-07
Identities = 31/94 (32%), Positives = 44/94 (46%), Gaps = 2/94 (2%)
Query: 96 PTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILE 155
P YP V EGE F+C V G P P +W +G +I S R V + + + L+
Sbjct: 1841 PDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRV--RYDGIHYLD 1898
Query: 156 IDEVSIEDVGIYRITVENELGRAEASARLEVITR 189
I + D G ++T EN G E +LE+ R
Sbjct: 1899 IVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQR 1932
Score = 51.2 bits (117), Expect = 3e-06
Identities = 41/146 (28%), Positives = 59/146 (40%), Gaps = 6/146 (4%)
Query: 46 TARLKIKQVTAEDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNK 105
T I +TA +E + A N G++ V R + P F+T FN
Sbjct: 26277 TLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELP-FHT--FN- 26332
Query: 106 VVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVG 165
V+ E + KG P +W KDG + + R+ V + + L I E S EDVG
Sbjct: 26333 -VKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTS-LSIKEASKEDVG 26390
Query: 166 IYRITVENELGRAEASARLEVITRSG 191
Y + V N G + V+ R G
Sbjct: 26391 TYELCVSNSAGSITVPITIIVLDRPG 26416
Score = 50.4 bits (115), Expect = 5e-06
Identities = 42/181 (23%), Positives = 79/181 (43%), Gaps = 15/181 (8%)
Query: 8 TVEFECQVTGNPDPDIRWFHY-AEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEA 66
TVEF+ + G P I+WF E++ F + T+ L + V A G YTC
Sbjct: 6273 TVEFKAILKGTPPFKIKWFKDDVELVSGPKCF-IGLEGSTSFLNLYSVDASKTGQYTCHV 6331
Query: 67 SNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYT-YPFNKVVEEGENVTFKCAVKGNPSP 125
+N +G L+V + P P F +K+V+ G++ +C + G+P
Sbjct: 6332 TNDVGSDSCTTMLLV------TEP-----PKFVKKLEASKIVKAGDSSRLECKIAGSPEI 6380
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
W ++ + S + + + + +++++ +S ED G + +N G S ++
Sbjct: 6381 RVVWFRNEHELPASDKYRMTFIDSV-AVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVI 6439
Query: 186 V 186
V
Sbjct: 6440 V 6440
Score = 50.4 bits (115), Expect = 5e-06
Identities = 30/93 (32%), Positives = 49/93 (52%), Gaps = 7/93 (7%)
Query: 96 PTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILE 155
P F +Y V+ G+++ + + G P P +W KDG + + RI V + + + L
Sbjct: 24161 PAFSSYS----VQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLD-LTTLS 24215
Query: 156 IDEVSIEDVGIYRITVENELGRAEASARLEVIT 188
I E +D G Y ITV N +G+ AS +E++T
Sbjct: 24216 IKETHKDDGGQYGITVANVVGQKTAS--IEIVT 24246
Score = 49.6 bits (113), Expect = 8e-06
Identities = 30/91 (32%), Positives = 43/91 (47%), Gaps = 1/91 (1%)
Query: 96 PTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILE 155
PT + N V EGE+VT +C + G PSP +W ++ I S + + I R++
Sbjct: 943 PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLM- 1001
Query: 156 IDEVSIEDVGIYRITVENELGRAEASARLEV 186
I E ED G + + NE G S L V
Sbjct: 1002 IREAFAEDSGRFTCSAVNEAGTVSTSCYLAV 1032
Score = 49.6 bits (113), Expect = 8e-06
Identities = 27/86 (31%), Positives = 45/86 (52%), Gaps = 3/86 (3%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRI-LEIDEVSIEDVG 165
V G+ + VKG P P +W K+G ++ R+ + +++ R+ L+I E D G
Sbjct: 18847 VRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDL--IQDLPRVELQIKEAVRADHG 18904
Query: 166 IYRITVENELGRAEASARLEVITRSG 191
Y I+ +N G A+ SA + V+ R G
Sbjct: 18905 KYIISAKNSSGHAQGSAIVNVLDRPG 18930
Score = 48.8 bits (111), Expect = 1e-05
Identities = 42/168 (25%), Positives = 62/168 (36%), Gaps = 12/168 (7%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
VE EC+VTG P ++ W IR + + L I + D G Y C SN
Sbjct: 5899 VELECEVTGTPPFEVTWLKNNREIRSSKKYTLTDRVSVFNLHITKCDPSDTGEYQCIVSN 5958
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G + + L P P+F N + TF+ V G+P +
Sbjct: 5959 EGGSCSCSTRVA------LKEP-----PSFIKKIENTTTVLKSSATFQSTVAGSPPISIT 6007
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG 176
W KD I+ + + + + L+I V G Y +NE G
Sbjct: 6008 WLKDDQILDEDDNVYISFVDSV-ATLQIRSVDNGHSGRYTCQAKNESG 6054
Score = 48.4 bits (110), Expect = 2e-05
Identities = 24/86 (27%), Positives = 41/86 (47%), Gaps = 1/86 (1%)
Query: 106 VVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVG 165
+ +E N K +KG P+P SW K + R++V E + L + + D G
Sbjct: 20920 LAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSV-ESSAVNTTLIVYDCQKSDAG 20978
Query: 166 IYRITVENELGRAEASARLEVITRSG 191
Y IT++N G E + ++V+ + G
Sbjct: 20979 KYTITLKNVAGTKEGTISIKVVGKPG 21004
Score = 48.4 bits (110), Expect = 2e-05
Identities = 27/103 (26%), Positives = 46/103 (44%), Gaps = 1/103 (0%)
Query: 106 VVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVG 165
+++ GE + V G P P W KDG + +A++ +K + ++ D D G
Sbjct: 22399 ILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTR-RDSG 22457
Query: 166 IYRITVENELGRAEASARLEVITRSGKFYGGLRAYSASPRKCL 208
Y +T N G A+ ++V+ R G G L + KC+
Sbjct: 22458 AYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCV 22500
Score = 48.4 bits (110), Expect = 2e-05
Identities = 37/165 (22%), Positives = 68/165 (41%), Gaps = 2/165 (1%)
Query: 51 IKQVTAEDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEG 110
I +T + + A N +G SN VV + S G + Y G
Sbjct: 27756 ISGLTQNSQYEFRVFARNAVGSI-SNPSEVVGPITCIDSYGGPVIDLPLEYTEVVKYRAG 27814
Query: 111 ENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRIT 170
+V + + G P+P W KD + +A + V+ ++ IL I + + G Y +
Sbjct: 27815 TSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASIL-IKDADRLNSGCYELK 27873
Query: 171 VENELGRAEASARLEVITRSGKFYGGLRAYSASPRKCLSYRRRPS 215
+ N +G A A+ R++++ + G G + + + K R P+
Sbjct: 27874 LRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEKITLLWRPPA 27918
Score = 48.0 bits (109), Expect = 3e-05
Identities = 44/190 (23%), Positives = 81/190 (42%), Gaps = 20/190 (10%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G T CQ + P+ WF +++ ++ + +L I V AED+G YTC
Sbjct: 9685 EGQTCTMTCQFSV-PNVKSEWFRNGRILKPQGRHKTEVEHKVHKLTIADVRAEDQGQYTC 9743
Query: 65 EASNCLGKAKSN-ACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
+ + A+ + T+R+ N VV E ++ TF+C V +
Sbjct: 9744 KYEDLETSAELRIEAEPIQFTKRIQ---------------NIVVSEHQSATFECEVSFDD 9788
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENE-LGRAEASA 182
+ +W K + +T S + + + + I V+ +D G+Y + E G A ++A
Sbjct: 9789 A-IVTWYKGPTELTESQKYNFR-NDGRCHYMTIHNVTPDDEGVYSVIARLEPRGEARSTA 9846
Query: 183 RLEVITRSGK 192
L + T+ K
Sbjct: 9847 ELYLTTKEIK 9856
Score = 47.6 bits (108), Expect = 3e-05
Identities = 30/83 (36%), Positives = 37/83 (44%)
Query: 104 NKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIED 163
N + EG VTF C + G P P +W KDG I R + ++ L I V ED
Sbjct: 1299 NYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPED 1358
Query: 164 VGIYRITVENELGRAEASARLEV 186
GIY N G A S +L V
Sbjct: 1359 EGIYTAFASNIKGNAICSGKLYV 1381
Score = 47.6 bits (108), Expect = 3e-05
Identities = 44/191 (23%), Positives = 78/191 (40%), Gaps = 18/191 (9%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G+T F C+++ + + WF + S + T +L++K+VT +D
Sbjct: 12514 EGETATFVCELS-HEKMHVVWFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLDDISQIKA 12572
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
+ + S A L V + P F +K E + +T KC V +
Sbjct: 12573 QVK----ELSSTAQLKVL----------EADPYFTVKLHDKTAVEKDEITLKCEVSKDVP 12618
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
W KDG I PS + ++K + + RIL+I + ++D G Y + +A +
Sbjct: 12619 --VKWFKDGEEIVPSPKYSIK-ADGLRRILKIKKADLKDKGEYVCDCGTDKTKANVTVEA 12675
Query: 185 EVITRSGKFYG 195
+I YG
Sbjct: 12676 RLIKVEKPLYG 12686
Score = 47.6 bits (108), Expect = 3e-05
Identities = 35/98 (35%), Positives = 41/98 (41%), Gaps = 9/98 (9%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADF------ESSYDDGTARLKIKQVTAEDE 59
G+ V VTG P P I W VI D E S + L I + ED+
Sbjct: 16340 GEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDK 16399
Query: 60 GTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPT 97
GTYT ASN LG N + VY SP R +A T
Sbjct: 16400 GTYTVTASNRLGSVFRNVHVEVYDR---PSPPRNLAVT 16434
Score = 47.6 bits (108), Expect = 3e-05
Identities = 31/108 (28%), Positives = 48/108 (44%), Gaps = 2/108 (1%)
Query: 106 VVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVG 165
VV+ GE + + G P P SW KDG I AR + + +L + + D G
Sbjct: 26727 VVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDN-HTLLTVKDCIRRDTG 26785
Query: 166 IYRITVENELGRAEASARLEVITRSGKFYGGLRAYSASPRKC-LSYRR 212
Y +T++N G + +V+ + G G L + KC LS+ R
Sbjct: 26786 QYVLTLKNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLSWGR 26833
Score = 47.6 bits (108), Expect = 3e-05
Identities = 24/76 (31%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
Query: 106 VVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVG 165
+ + GE+V KG P P +W KD + AR ++ E + +L I +V+ D G
Sbjct: 28209 IAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSI-ENTDSSSLLTIPQVTRNDTG 28267
Query: 166 IYRITVENELGRAEAS 181
Y +T+EN +G ++S
Sbjct: 28268 KYILTIENGVGEPKSS 28283
Score = 46.8 bits (106), Expect = 6e-05
Identities = 34/94 (36%), Positives = 46/94 (48%), Gaps = 3/94 (3%)
Query: 95 APTFYTYPFNKVVE-EGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRI 153
APTF T P VV EG TF+ + G P P SW +DG +I+ S V+ R
Sbjct: 5 APTF-TQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRA 63
Query: 154 -LEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
L I V+ + G Y + N G+A ++A L V
Sbjct: 64 KLTIPAVTKANSGRYSLKATNGSGQATSTAELLV 97
Score = 46.8 bits (106), Expect = 6e-05
Identities = 27/85 (31%), Positives = 41/85 (48%), Gaps = 3/85 (3%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
++ G+ + +KG P P +W K+ ARI V + LEI + ED GI
Sbjct: 18157 IKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTP---VGSKLEIRNAAHEDGGI 18213
Query: 167 YRITVENELGRAEASARLEVITRSG 191
Y +TVEN G S ++ V+ + G
Sbjct: 18214 YSLTVENPAGSKTVSVKVLVLDKPG 18238
Score = 46.0 bits (104), Expect = 1e-04
Identities = 42/184 (22%), Positives = 67/184 (36%), Gaps = 12/184 (6%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G ++ E TG + W I + T L+I T D G Y+CE
Sbjct: 6927 GKSIILESTYTGTLPISVTWKKDGFNITTSEKCNIVTTEKTCILEILNSTKRDAGQYSCE 6986
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
N G+ + C + T P F T G++V+ +C V G P
Sbjct: 6987 IENEAGR---DVCGALVSTLE--------PPYFVTELEPLEAAVGDSVSLQCQVAGTPEI 7035
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
SW K + + P+ + ++ ++V+I D G Y EN +G A +
Sbjct: 7036 TVSWYKGDTKLRPTPEYRTYFTNNVATLV-FNKVNINDSGEYTCKAENSIGTASSKTVFR 7094
Query: 186 VITR 189
+ R
Sbjct: 7095 IQER 7098
Score = 45.6 bits (103), Expect = 1e-04
Identities = 23/93 (24%), Positives = 46/93 (49%), Gaps = 1/93 (1%)
Query: 106 VVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVG 165
+++ GE++ K V+G P P +W KDG I + + + + + + + + G
Sbjct: 28896 IIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLF-VRDATRDHRG 28954
Query: 166 IYRITVENELGRAEASARLEVITRSGKFYGGLR 198
+Y + +N G A+A +++V GK G +R
Sbjct: 28955 VYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIR 28987
Score = 45.6 bits (103), Expect = 1e-04
Identities = 27/95 (28%), Positives = 43/95 (45%), Gaps = 5/95 (5%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+++ + V G P P + WF I + E + G+ L ++ T + G YT E
Sbjct: 28900 GESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVE 28959
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYT 100
A N G AK+ + V T PG+ + P +T
Sbjct: 28960 AKNASGSAKAEIKVKVQDT-----PGKVVGPIRFT 28989
Score = 45.2 bits (102), Expect = 2e-04
Identities = 49/189 (25%), Positives = 75/189 (39%), Gaps = 21/189 (11%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G T EC+V+ + ++WF I +E D +L I T ED TYTC
Sbjct: 13225 EGATAVLECEVS-RENAKVKWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTC 13283
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
+A + K N +V H L R + + V E E F+C + +
Sbjct: 13284 DAKDF--KTSCNLNVVPPHVEFL----RPLT--------DLQVREKEMARFECEL-SREN 13328
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
W KDG+ I + + K + RIL I++ ++D Y E+ A S L
Sbjct: 13329 AKVKWFKDGAEIKKGKKYDIISKGAV-RILVINKCLLDDEAEYSC----EVRTARTSGML 13383
Query: 185 EVITRSGKF 193
V+ F
Sbjct: 13384 TVLEEEAVF 13392
Score = 44.8 bits (101), Expect = 2e-04
Identities = 25/78 (32%), Positives = 38/78 (48%), Gaps = 2/78 (2%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYD--DGTARLKIKQVTAEDEGTY 62
+G +V F CQV GNP P + W + ++ SY+ G +L I A+D G Y
Sbjct: 1095 EGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEY 1154
Query: 63 TCEASNCLGKAKSNACLV 80
T N G+ ++A L+
Sbjct: 1155 TIVVRNKHGETSASASLL 1172
Score = 44.8 bits (101), Expect = 2e-04
Identities = 31/112 (27%), Positives = 46/112 (41%), Gaps = 4/112 (3%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G+T F C+VTG P P + W+ ++IR F Y DG L I + D G
Sbjct: 1854 EGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRY-DGIHYLDIVDCKSYDTGEVKV 1912
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGR---QMAPTFYTYPFNKVVEEGENV 113
A N G + L + S R + P F+ + K+ E + V
Sbjct: 1913 TAENPEGVIEHKVKLEIQQREDFRSVLRRAPEPRPEFHVHEPGKLQFEVQKV 1964
Score = 44.8 bits (101), Expect = 2e-04
Identities = 51/183 (27%), Positives = 70/183 (38%), Gaps = 15/183 (8%)
Query: 6 GDTVEFECQVTGNPDPDIR-WFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
G + FEC V+ P I W IR+ D +L I V D G YTC
Sbjct: 12060 GSSAIFECLVS--PSTAITTWMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSDAGEYTC 12117
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
+ S A LVV P R + T V +G+ + C + N
Sbjct: 12118 VLRLGNKEKTSTAKLVVEEL-----PVRFVK----TLEEEVTVVKGQPLYLSCEL--NKE 12166
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
W KDG I+ V +MR L I++ D G Y +TVEN E S+ +
Sbjct: 12167 RDVVWRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGTYTVTVEN-ANNLECSSCV 12225
Query: 185 EVI 187
+V+
Sbjct: 12226 KVV 12228
Score = 44.8 bits (101), Expect = 2e-04
Identities = 46/163 (28%), Positives = 67/163 (41%), Gaps = 19/163 (11%)
Query: 53 QVTAED-----EGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVV 107
Q T ED E + +A N G +K +A + +R P P+ F +V
Sbjct: 17002 QFTVEDLVEGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMP-----PSIDLKEFMEV- 17055
Query: 108 EEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSI------ 161
EEG NV +KG P P +W K P + V + +++ D ++
Sbjct: 17056 EEGTNVNIVAKIKGVPFPTLTWFK-APPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSR 17114
Query: 162 -EDVGIYRITVENELGRAEASARLEVITRSGKFYGGLRAYSAS 203
D G+Y IT N LG A RL V+ R G G ++ S S
Sbjct: 17115 RSDTGLYTITAVNNLGTASKEMRLNVLGRPGPPVGPIKFESVS 17157
Score = 44.8 bits (101), Expect = 2e-04
Identities = 34/142 (23%), Positives = 58/142 (40%), Gaps = 7/142 (4%)
Query: 51 IKQVTAEDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKV-VEE 109
+K + D Y A N +G+ K + C T+ ++ PT + +K+ +
Sbjct: 17705 VKGLKEGDTYEYRVSAVNIVGQGKPSFC-----TKPITCKDELAPPTLHLDFRDKLTIRV 17759
Query: 110 GENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRI 169
GE G P P SW KD + + R +K + + +I + D G Y +
Sbjct: 17760 GEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKI-KAKRSDSGKYCV 17818
Query: 170 TVENELGRAEASARLEVITRSG 191
VEN G + ++ V+ R G
Sbjct: 17819 VVENSTGSRKGFCQVNVVDRPG 17840
Score = 44.8 bits (101), Expect = 2e-04
Identities = 26/99 (26%), Positives = 43/99 (43%), Gaps = 1/99 (1%)
Query: 93 QMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMR 152
Q+ P P ++ G+ + + V G P P W K + S+ + V K +
Sbjct: 19823 QLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAV-HKADSSS 19881
Query: 153 ILEIDEVSIEDVGIYRITVENELGRAEASARLEVITRSG 191
IL I +V+ +D G Y +T EN G ++ V+ G
Sbjct: 19882 ILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPG 19920
Score = 44.0 bits (99), Expect = 4e-04
Identities = 45/184 (24%), Positives = 74/184 (40%), Gaps = 20/184 (10%)
Query: 5 DGDTVEFECQVTGN-PDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYT 63
D D V FE + N P+ + W+ E + FE S D L++K +D+G Y
Sbjct: 9597 DNDAV-FEIDIKINYPEIKLSWYKGTEKLEPSDKFEISIDGDRHTLRVKNCQLKDQGNYR 9655
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
+ AK L V + P + + + ++EG+ T C P
Sbjct: 9656 LVCGPHIASAK----LTV------------IEPAWERHLQDVTLKEGQTCTMTCQF-SVP 9698
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
+ + W ++G I+ P R + + ++ + L I +V ED G Y E+ AE
Sbjct: 9699 NVKSEWFRNGRILKPQGRHKTEVEHKVHK-LTIADVRAEDQGQYTCKYEDLETSAELRIE 9757
Query: 184 LEVI 187
E I
Sbjct: 9758 AEPI 9761
Score = 44.0 bits (99), Expect = 4e-04
Identities = 36/145 (24%), Positives = 59/145 (40%), Gaps = 7/145 (4%)
Query: 48 RLKIKQVTAEDEGTYTCEASNCLGKAKS-NACLVVYHTRRLSSPGRQMAPTFYTYPFNKV 106
R + + A +E + A N GK S + RL++P + F V
Sbjct: 29239 RYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQ---THV 29295
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
V G ++ A +G P+P A W K S ++ A I + L ++ + D G
Sbjct: 29296 VRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRADIHTTDS---FSTLTVENCNRNDAGK 29352
Query: 167 YRITVENELGRAEASARLEVITRSG 191
Y +TVEN G + ++V+ G
Sbjct: 29353 YTLTVENNSGSKSITFTVKVLDTPG 29377
Score = 43.6 bits (98), Expect = 6e-04
Identities = 30/103 (29%), Positives = 46/103 (44%), Gaps = 6/103 (5%)
Query: 92 RQMAPTFYTYPFNK---VVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKE 148
R+MAP F + VV G ++ +KG P+P +W KD + A I E
Sbjct: 21697 REMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANI---ENT 21753
Query: 149 EIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVITRSG 191
E +L I E + D G + +T+EN G+ + V+ G
Sbjct: 21754 ESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPG 21796
Score = 43.6 bits (98), Expect = 6e-04
Identities = 24/69 (34%), Positives = 34/69 (49%), Gaps = 3/69 (4%)
Query: 119 VKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRA 178
+KG P P W+K I+T A+I V +L ID V+ D G Y +T+EN G
Sbjct: 26058 IKGRPEPEVKWEKAEGILTDRAQIEVTSS---FTMLVIDNVTRFDSGRYNLTLENNSGSK 26114
Query: 179 EASARLEVI 187
A + V+
Sbjct: 26115 TAFVNVRVL 26123
Score = 43.2 bits (97), Expect = 7e-04
Identities = 24/85 (28%), Positives = 36/85 (42%), Gaps = 1/85 (1%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
V+ G + V G P P +W K I+ RIT++ + + +D D G
Sbjct: 14629 VKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDS-KRSDTGT 14687
Query: 167 YRITVENELGRAEASARLEVITRSG 191
Y I N GRA A + V+ + G
Sbjct: 14688 YIIEAVNVCGRATAVVEVNVLDKPG 14712
Score = 43.2 bits (97), Expect = 7e-04
Identities = 29/88 (32%), Positives = 41/88 (46%), Gaps = 5/88 (5%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSII---TPSARITVKE--KEEIMRILEIDEVSI 161
V+ GE V V G P P W K+ ++I T + +IT +E + E L I +
Sbjct: 16337 VKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVR 16396
Query: 162 EDVGIYRITVENELGRAEASARLEVITR 189
ED G Y +T N LG + +EV R
Sbjct: 16397 EDKGTYTVTASNRLGSVFRNVHVEVYDR 16424
Score = 43.2 bits (97), Expect = 7e-04
Identities = 26/103 (25%), Positives = 47/103 (45%), Gaps = 4/103 (3%)
Query: 107 VEEGENVTFKCAVKGNPSPWASW--DKDGSIITPSARITVKEKEEIMRILEIDEVSIEDV 164
V+ G+ + + V+G P P +W DKD + +T S R+ + + + + + + D
Sbjct: 19140 VKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSK-FSLTKAKRSDG 19198
Query: 165 GIYRITVENELGRAEASARLEVITRSGKFYGGLRAYSASPRKC 207
G Y +T N G A A + V+ + G L+ S +C
Sbjct: 19199 GKYVVTATNTAGSFVAYATVNVLDKPGP-VRNLKIVDVSSDRC 19240
Score = 43.2 bits (97), Expect = 7e-04
Identities = 26/91 (28%), Positives = 39/91 (42%), Gaps = 5/91 (5%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+ ++ E V G P P+I W E ++ + L IK+ +D G YT
Sbjct: 25253 GEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVT 25312
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAP 96
A+N G A N ++V L PG + P
Sbjct: 25313 ATNSAGTATENLSVIV-----LEKPGPPVGP 25338
Score = 42.7 bits (96), Expect = 0.001
Identities = 27/95 (28%), Positives = 38/95 (40%), Gaps = 5/95 (5%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+ E V+G P P + W + + A E D + L K T D G YT
Sbjct: 22403 GEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLT 22462
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYT 100
A+N G AK +++ + L PG P T
Sbjct: 22463 ATNPGGFAKH-----IFNVKVLDRPGPPEGPLAVT 22492
Score = 42.3 bits (95), Expect = 0.001
Identities = 23/76 (30%), Positives = 34/76 (44%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G T+ +V G P+PDI W +V+ + D L+IK+ D G Y
Sbjct: 18850 GQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKYIIS 18909
Query: 66 ASNCLGKAKSNACLVV 81
A N G A+ +A + V
Sbjct: 18910 AKNSSGHAQGSAIVNV 18925
Score = 41.9 bits (94), Expect = 0.002
Identities = 38/138 (27%), Positives = 59/138 (42%), Gaps = 10/138 (7%)
Query: 54 VTAEDEGTYTCEASNCLGKAKSNACLV----VYHTRRLSSPGRQMAPTFYTYPFNKVVEE 109
++AE+EG ++ E L K L+ VY T+ S P F N +
Sbjct: 3460 LSAEEEGLHSAELQ--LSKINETLELLSESPVYSTK-FDSEKEGTGPIFIKEVSNADISM 3516
Query: 110 GENVTFKCAVKGNPSPWASWDKDGSIITPSARIT-VKEKEEIMRILEIDEVSIEDVGIYR 168
G+ T V G P P W +G ++TPSA V + ++ I+ +ED G Y
Sbjct: 3517 GDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILF--TKLEDEGEYT 3574
Query: 169 ITVENELGRAEASARLEV 186
N+ G+ SA L++
Sbjct: 3575 CMASNDYGKTICSAYLKI 3592
Score = 41.9 bits (94), Expect = 0.002
Identities = 30/126 (23%), Positives = 50/126 (39%), Gaps = 4/126 (3%)
Query: 51 IKQVTAEDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEG 110
++ +T +E T+ A N G++ V + P + + K G
Sbjct: 21951 VRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVIAKA---G 22007
Query: 111 ENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRIT 170
+N+ + V G P P +W K I+ + R+ E IL I+E D G Y +T
Sbjct: 22008 DNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNF-ETTATSTILNINECVRSDSGPYPLT 22066
Query: 171 VENELG 176
N +G
Sbjct: 22067 ARNIVG 22072
Score = 41.5 bits (93), Expect = 0.002
Identities = 27/97 (27%), Positives = 43/97 (44%), Gaps = 2/97 (2%)
Query: 96 PTFYTYPFNK-VVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRIL 154
P + FN V GE++ G P+P +W KD + + R+ E E +L
Sbjct: 23074 PPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNA-ESTENNSLL 23132
Query: 155 EIDEVSIEDVGIYRITVENELGRAEASARLEVITRSG 191
I + EDVG Y + + N G A + + V+ + G
Sbjct: 23133 TIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPG 23169
Score = 41.1 bits (92), Expect = 0.003
Identities = 25/102 (24%), Positives = 43/102 (42%), Gaps = 1/102 (0%)
Query: 106 VVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVG 165
VV GE+ + G P P W K ++ +AR+ +K + + D V + D G
Sbjct: 23481 VVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRV-DSG 23539
Query: 166 IYRITVENELGRAEASARLEVITRSGKFYGGLRAYSASPRKC 207
Y + +N G + ++V+ R G G + + KC
Sbjct: 23540 NYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISGVTAEKC 23581
Score = 41.1 bits (92), Expect = 0.003
Identities = 27/102 (26%), Positives = 41/102 (40%), Gaps = 1/102 (0%)
Query: 106 VVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVG 165
VV GE + V G P P W + I SAR +K + ++ D + I D G
Sbjct: 24563 VVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRI-DGG 24621
Query: 166 IYRITVENELGRAEASARLEVITRSGKFYGGLRAYSASPRKC 207
Y + N G ++V+ R G G ++ + KC
Sbjct: 24622 QYILRASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKC 24663
Score = 41.1 bits (92), Expect = 0.003
Identities = 27/103 (26%), Positives = 44/103 (42%), Gaps = 2/103 (1%)
Query: 106 VVEEGENVTFKCAVKGNPSPWASWDKDG-SIITPSARITVKEKEEIMRILEIDEVSIEDV 164
VV GE + ++G P P W KDG + +AR+ +K + L + + D
Sbjct: 25645 VVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQ-KTTLVVKDCIRTDG 25703
Query: 165 GIYRITVENELGRAEASARLEVITRSGKFYGGLRAYSASPRKC 207
G Y + + N G ++V+ R G G L+ + KC
Sbjct: 25704 GQYILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKC 25746
Score = 40.7 bits (91), Expect = 0.004
Identities = 28/95 (29%), Positives = 37/95 (38%)
Query: 92 RQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIM 151
R P F P + EG+ F V G P P W DG I V KE+
Sbjct: 1453 RLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGT 1512
Query: 152 RILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
+ L I + D G + + +N GR+ S L V
Sbjct: 1513 QSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTV 1547
Score = 39.9 bits (89), Expect = 0.007
Identities = 43/177 (24%), Positives = 83/177 (46%), Gaps = 22/177 (12%)
Query: 11 FECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCL 70
FEC +T + ++ W ++I+ F+ D L I +DEG YT E
Sbjct: 12432 FECVLTR--EANVIWSKGPDIIKSSDKFDIIADGKKHILVINDSQFDDEGVYTAEVE--- 12486
Query: 71 GKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWD 130
GK K++A L V R + M+P ++ V+EGE TF C + + W
Sbjct: 12487 GK-KTSARLFVTGIRL-----KFMSPL-----EDQTVKEGETATFVCEL-SHEKMHVVWF 12534
Query: 131 KDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVI 187
K+ + + S + + + + + LE+ EV+++D+ ++ ++ ++A+L+V+
Sbjct: 12535 KNDAKLHTSRTVLISSEGKTHK-LEMKEVTLDDIS----QIKAQVKELSSTAQLKVL 12586
Score = 39.9 bits (89), Expect = 0.007
Identities = 24/99 (24%), Positives = 42/99 (42%), Gaps = 1/99 (1%)
Query: 110 GENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRI 169
G T + G P+P +W + + + R+++ ++ L + + D G Y +
Sbjct: 29589 GSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKD-RTTLTVKDSMRGDSGRYFL 29647
Query: 170 TVENELGRAEASARLEVITRSGKFYGGLRAYSASPRKCL 208
T+EN G S + VI R G G + S S C+
Sbjct: 29648 TLENTAGVKTFSVTVVVIGRPGPVTGPIEVSSVSAESCV 29686
Score = 39.5 bits (88), Expect = 0.009
Identities = 23/66 (34%), Positives = 27/66 (40%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+T E V G P P I W + I + A E D A L +K D G Y
Sbjct: 24567 GETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILR 24626
Query: 66 ASNCLG 71
ASN G
Sbjct: 24627 ASNVAG 24632
Score = 38.3 bits (85), Expect = 0.021
Identities = 22/80 (27%), Positives = 35/80 (43%), Gaps = 1/80 (1%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
V+ G+ F + G P P SW K+ +++ + + +L I E ED +
Sbjct: 3250 VQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLI-EAFPEDAAV 3308
Query: 167 YRITVENELGRAEASARLEV 186
Y +N+ G A SA L V
Sbjct: 3309 YTCEAKNDYGVATTSASLSV 3328
Score = 38.3 bits (85), Expect = 0.021
Identities = 29/97 (29%), Positives = 44/97 (45%), Gaps = 4/97 (4%)
Query: 95 APTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRIL 154
AP T + VV+ G+ +T P A W K+ ++ T E+ RIL
Sbjct: 13926 APKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKTIDTTAEQTSF-RIL 13984
Query: 155 EIDEVSIEDVGIYRITVENELGRAEASARLEVITRSG 191
E + D G Y+I ++N+ G+AE L+VI G
Sbjct: 13985 EAKK---GDKGRYKIVLQNKHGKAEGFINLKVIDVPG 14018
Score = 38.3 bits (85), Expect = 0.021
Identities = 24/93 (25%), Positives = 40/93 (43%), Gaps = 7/93 (7%)
Query: 106 VVEEGENVTFKCAVKGNPSPWASWDKDGSI-------ITPSARITVKEKEEIMRILEIDE 158
V + G + +KG P+P +SW+ DG + E E ++ I E
Sbjct: 16748 VCKAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPE 16807
Query: 159 VSIEDVGIYRITVENELGRAEASARLEVITRSG 191
G Y IT +N+ G+ A+ R++V+ G
Sbjct: 16808 CKRSHTGKYSITAKNKAGQKTANCRVKVMDVPG 16840
Score = 38.3 bits (85), Expect = 0.021
Identities = 29/101 (28%), Positives = 42/101 (41%), Gaps = 5/101 (4%)
Query: 95 APTFYTYPFNK---VVEEGENVTFKC-AVKGNPSPWASWDKDGSIITPSARITVKEKEEI 150
APT P K ++ G+ + ++ G P P +SW K G I PS IT
Sbjct: 21302 APTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPS-DITQITSTPT 21360
Query: 151 MRILEIDEVSIEDVGIYRITVENELGRAEASARLEVITRSG 191
+L I + +D G Y IT N G ++ V+ G
Sbjct: 21361 SSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDVPG 21401
Score = 38.3 bits (85), Expect = 0.021
Identities = 22/91 (24%), Positives = 36/91 (39%), Gaps = 5/91 (5%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G++ + + + G P P I+W + + + A E D L +K D G Y +
Sbjct: 23485 GESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILK 23544
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAP 96
A N G+ V + + L PG P
Sbjct: 23545 AKNVAGERS-----VTVNVKVLDRPGPPEGP 23570
Score = 38.3 bits (85), Expect = 0.021
Identities = 25/92 (27%), Positives = 39/92 (42%), Gaps = 2/92 (2%)
Query: 101 YPFNKV-VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEV 159
+P + V V G N+ + G P P + +DG + + R + E + I + E
Sbjct: 27408 FPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTI-NLKES 27466
Query: 160 SIEDVGIYRITVENELGRAEASARLEVITRSG 191
D G Y IT N G +A + V+ R G
Sbjct: 27467 VTADAGRYEITAANSSGTTKAFINIVVLDRPG 27498
Score = 37.9 bits (84), Expect = 0.027
Identities = 29/98 (29%), Positives = 43/98 (43%), Gaps = 1/98 (1%)
Query: 89 SPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKE 148
SP + AP + ++ V +G + F+ V G P P W K+G I S RI E
Sbjct: 2072 SPSME-APKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPE 2130
Query: 149 EIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
+ + L I +V+ ED + N G + A L V
Sbjct: 2131 DNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLV 2168
Score = 37.5 bits (83), Expect = 0.036
Identities = 21/86 (24%), Positives = 38/86 (44%), Gaps = 1/86 (1%)
Query: 106 VVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVG 165
++ G + VKG P P +W K + + +K + L + V+ D G
Sbjct: 20631 ILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTD-FDTFLRCENVNKYDAG 20689
Query: 166 IYRITVENELGRAEASARLEVITRSG 191
Y +T+EN G+ E + ++V+ G
Sbjct: 20690 KYILTLENSCGKKEYTIVVKVLDTPG 20715
Score = 37.1 bits (82), Expect = 0.048
Identities = 24/86 (27%), Positives = 35/86 (40%), Gaps = 3/86 (3%)
Query: 106 VVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVG 165
VV G + KG P+P +W ++ T +I EK L ID D G
Sbjct: 24962 VVRAGGSARIHIPFKGRPTPEITWSREEGEFTDKVQI---EKGVNYTQLSIDNCDRNDAG 25018
Query: 166 IYRITVENELGRAEASARLEVITRSG 191
Y + +EN G A ++V+ G
Sbjct: 25019 KYILKLENSSGSKSAFVTVKVLDTPG 25044
Score = 37.1 bits (82), Expect = 0.048
Identities = 21/75 (28%), Positives = 32/75 (42%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+ V+ G P P + W + + A + D ++ L I QVT D G Y
Sbjct: 28213 GEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILT 28272
Query: 66 ASNCLGKAKSNACLV 80
N +G+ KS+ V
Sbjct: 28273 IENGVGEPKSSTVSV 28287
Score = 36.7 bits (81), Expect = 0.063
Identities = 40/162 (24%), Positives = 69/162 (42%), Gaps = 17/162 (10%)
Query: 10 EFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNC 69
E EC V+ + + +W+H ++ + + G L +K VT ED+G Y+
Sbjct: 2285 ELECIVSPE-NIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVID-- 2341
Query: 70 LGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASW 129
K C +L R +A ++ V EG+ V + V S W
Sbjct: 2342 ---GKKTTC-------KLKMKPRPIA--ILQGLSDQKVCEGDIVQLEVKV-SLESVEGVW 2388
Query: 130 DKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITV 171
KDG + PS R+ + ++ +L I++++ ED G Y T+
Sbjct: 2389 MKDGQEVQPSDRVHIVIDKQ-SHMLLIEDMTKEDAGNYSFTI 2429
Score = 36.3 bits (80), Expect = 0.084
Identities = 21/79 (26%), Positives = 34/79 (43%), Gaps = 2/79 (2%)
Query: 11 FECQVT--GNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
FEC++T G+P + W H + + + G L + D G TC A+N
Sbjct: 1722 FECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATN 1781
Query: 69 CLGKAKSNACLVVYHTRRL 87
G ++A L+V + L
Sbjct: 1782 KYGTDHTSATLIVKDEKSL 1800
Score = 36.3 bits (80), Expect = 0.084
Identities = 23/81 (28%), Positives = 35/81 (43%), Gaps = 3/81 (3%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
+ G ++ +KG P+P W K I +A I V L +D V+ D G
Sbjct: 23881 IRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSS---FTSLVLDNVNRYDSGK 23937
Query: 167 YRITVENELGRAEASARLEVI 187
Y +T+EN G A + V+
Sbjct: 23938 YTLTLENSSGTKSAFVTVRVL 23958
Score = 35.9 bits (79), Expect = 0.11
Identities = 45/178 (25%), Positives = 69/178 (38%), Gaps = 22/178 (12%)
Query: 11 FECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCL 70
FEC+V NPD W + + + S D RL I +D G YT + +
Sbjct: 2639 FECEVA-NPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTYKVAT-- 2695
Query: 71 GKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWD 130
+K++A +L ++ T N V E ++ F + W
Sbjct: 2696 --SKTSA--------KLKVEAVKIKKTLK----NLTVTETQDAVFTVELTHPNVKGVQWI 2741
Query: 131 KDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVIT 188
K+G ++ + + + K I L I +I D +Y LGR ASARL V T
Sbjct: 2742 KNGVVLESNEKYAISVKGTIYS-LRIKNCAIVDESVYGF----RLGRLGASARLHVET 2794
Score = 35.5 bits (78), Expect = 0.15
Identities = 21/76 (27%), Positives = 31/76 (40%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G + E V G P P +W + + + D ++ L IK VT +D G Y+
Sbjct: 19840 GKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLT 19899
Query: 66 ASNCLGKAKSNACLVV 81
A N G +VV
Sbjct: 19900 AENSSGTDTQKIKVVV 19915
Score = 35.1 bits (77), Expect = 0.19
Identities = 22/73 (30%), Positives = 31/73 (42%), Gaps = 3/73 (4%)
Query: 119 VKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRA 178
+KG P+P W +D A I E +L + V+ D G Y +TVEN G
Sbjct: 22811 IKGRPAPEVKWARDHGESLDKASI---ESTSSYTLLIVGNVNRFDSGKYILTVENSSGSK 22867
Query: 179 EASARLEVITRSG 191
A + V+ G
Sbjct: 22868 SAFVNVRVLDTPG 22880
Score = 34.7 bits (76), Expect = 0.26
Identities = 19/68 (27%), Positives = 27/68 (39%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G +E VTG P+P I W +++ + + I D GTY E
Sbjct: 14632 GTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIE 14691
Query: 66 ASNCLGKA 73
A N G+A
Sbjct: 14692 AVNVCGRA 14699
Score = 34.7 bits (76), Expect = 0.26
Identities = 25/91 (27%), Positives = 32/91 (35%), Gaps = 5/91 (5%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G TV F + G P P +W I+ + D+ ++ L IK D G Y
Sbjct: 18452 GTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQIT 18511
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAP 96
SN G V H L PG P
Sbjct: 18512 VSNAAGSK-----TVAVHLTVLDVPGPPTGP 18537
Score = 34.7 bits (76), Expect = 0.26
Identities = 22/71 (30%), Positives = 31/71 (43%), Gaps = 1/71 (1%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
V G NV + KG P P SW KDG + S + + E + L I E G
Sbjct: 28502 VRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKI-TLSIKNAKKEHGGK 28560
Query: 167 YRITVENELGR 177
Y + ++N + R
Sbjct: 28561 YTVILDNAVCR 28571
Score = 34.3 bits (75), Expect = 0.34
Identities = 38/174 (21%), Positives = 69/174 (39%), Gaps = 19/174 (10%)
Query: 7 DTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEA 66
D F CQ++ +++W+ I++ ++ D RL IK +DE Y C
Sbjct: 13765 DDAVFSCQLS-REKANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKDCRLDDECEYACGV 13823
Query: 67 SNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVE-EGENVTFKCAVKGNPSP 125
+ KS A L V + P P ++E G +V F A
Sbjct: 13824 ED----RKSRARLFV-----------EEIPVEIIRPPQDILEAPGADVVF-LAELNKDKV 13867
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAE 179
W ++ ++ + + + +I R L+I ++ D G YR +++ RA+
Sbjct: 13868 EVQWLRNNMVVVQGDKHQMMSEGKIHR-LQICDIKPRDQGEYRFIAKDKEARAK 13920
Score = 34.3 bits (75), Expect = 0.34
Identities = 16/67 (23%), Positives = 27/67 (40%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
GD ++ E V G P P + W ++++ + L I + D G Y
Sbjct: 22007 GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLT 22066
Query: 66 ASNCLGK 72
A N +G+
Sbjct: 22067 ARNIVGE 22073
Score = 34.3 bits (75), Expect = 0.34
Identities = 20/86 (23%), Positives = 37/86 (43%), Gaps = 3/86 (3%)
Query: 106 VVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVG 165
+V+ G + T +G P P W K + + A + + L I+ + D G
Sbjct: 27124 IVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRAYVDTTDSR---TSLTIENANRNDSG 27180
Query: 166 IYRITVENELGRAEASARLEVITRSG 191
Y +T++N L A + ++V+ G
Sbjct: 27181 KYTLTIQNVLSAASLTLVVKVLDTPG 27206
Score = 33.5 bits (73), Expect = 0.59
Identities = 36/161 (22%), Positives = 61/161 (37%), Gaps = 17/161 (10%)
Query: 7 DTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEA 66
+ FEC+++ + ++WF I+ ++ L I + +DE Y+CE
Sbjct: 13316 EMARFECELS-RENAKVKWFKDGAEIKKGKKYDIISKGAVRILVINKCLLDDEAEYSCEV 13374
Query: 67 SNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPW 126
A+++ L V + + + +A N V E + + C V P
Sbjct: 13375 RT----ARTSGMLTVLEEEAVFT--KNLA--------NIEVSETDTIKLVCEV-SKPGAE 13419
Query: 127 ASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIY 167
W K I + R + E RIL I +ED G Y
Sbjct: 13420 VIWYKGDEEIIETGRYEIL-TEGRKRILVIQNAHLEDAGNY 13459
Score = 33.1 bits (72), Expect = 0.78
Identities = 20/62 (32%), Positives = 26/62 (41%), Gaps = 1/62 (1%)
Query: 7 DTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEA 66
D +FEC+V+ P RW + I FE D + IK EDE Y EA
Sbjct: 12782 DEAKFECEVSREPKT-FRWLKGTQEITGDDRFELIKDGTKHSMVIKSAAFEDEAKYMFEA 12840
Query: 67 SN 68
+
Sbjct: 12841 ED 12842
Score = 32.7 bits (71), Expect = 1.0
Identities = 18/76 (23%), Positives = 29/76 (38%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G V + V G P P + W +++ + + L++ V +D G YT
Sbjct: 20237 GTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTIT 20296
Query: 66 ASNCLGKAKSNACLVV 81
A N G + L V
Sbjct: 20297 AENSSGSKSATIKLKV 20312
Score = 32.7 bits (71), Expect = 1.0
Identities = 20/67 (29%), Positives = 29/67 (43%), Gaps = 1/67 (1%)
Query: 6 GDTVEFEC-QVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
GDT+ + G P P W + IR + + ++ L IK T +D G YT
Sbjct: 21320 GDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTI 21379
Query: 65 EASNCLG 71
A+N G
Sbjct: 21380 TATNPFG 21386
Score = 32.7 bits (71), Expect = 1.0
Identities = 20/91 (21%), Positives = 35/91 (38%), Gaps = 5/91 (5%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+ ++ + G P P + W ++ + + + L IK ED G Y +
Sbjct: 23089 GEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVK 23148
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAP 96
+N G+A ++V L PG P
Sbjct: 23149 LTNSAGEAIETLNVIV-----LDKPGPPTGP 23174
Score = 32.3 bits (70), Expect = 1.4
Identities = 16/75 (21%), Positives = 29/75 (38%)
Query: 7 DTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEA 66
+ ++ + G P + W + +++ S L IK+ + ED GTY
Sbjct: 26337 EQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCV 26396
Query: 67 SNCLGKAKSNACLVV 81
SN G ++V
Sbjct: 26397 SNSAGSITVPITIIV 26411
Score = 31.9 bits (69), Expect = 1.8
Identities = 22/86 (25%), Positives = 35/86 (40%), Gaps = 2/86 (2%)
Query: 106 VVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVG 165
+V G + V+G P+P +W K G I R + + M L I + +D G
Sbjct: 19544 IVRAGCPIRLFAIVRGRPAPKVTWRKVG--IDNVVRKGQVDLVDTMAFLVIPNSTRDDSG 19601
Query: 166 IYRITVENELGRAEASARLEVITRSG 191
Y +T+ N G + V+ G
Sbjct: 19602 KYSLTLVNPAGEKAVFVNVRVLDTPG 19627
Score = 31.5 bits (68), Expect = 2.4
Identities = 10/32 (31%), Positives = 19/32 (59%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITP 138
V+ G+ + ++ G+P P +W KD ++I P
Sbjct: 15618 VKRGDEIALDASISGSPYPTITWIKDENVIVP 15649
Score = 31.5 bits (68), Expect = 2.4
Identities = 21/79 (26%), Positives = 28/79 (35%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G T+ V G P P I W +RD + D L+ + V D G Y
Sbjct: 20635 GVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILT 20694
Query: 66 ASNCLGKAKSNACLVVYHT 84
N GK + + V T
Sbjct: 20695 LENSCGKKEYTIVVKVLDT 20713
Score = 31.1 bits (67), Expect = 3.2
Identities = 22/102 (21%), Positives = 39/102 (38%), Gaps = 3/102 (2%)
Query: 106 VVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVG 165
VV G + V G P P +W+ + + A I E I + I G
Sbjct: 17462 VVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATI---ETTAISSSMVIKNCQRSHQG 17518
Query: 166 IYRITVENELGRAEASARLEVITRSGKFYGGLRAYSASPRKC 207
+Y + +NE G + + ++V+ G A++ + C
Sbjct: 17519 VYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESC 17560
Score = 31.1 bits (67), Expect = 3.2
Identities = 42/179 (23%), Positives = 63/179 (35%), Gaps = 20/179 (11%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+ ++ + G P P I W I + A E D L +K D G Y
Sbjct: 26731 GEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLT 26790
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVK-GNPS 124
N G V + + L PG P N + E KC++ G P
Sbjct: 26791 LKNVAGTRS-----VAVNCKVLDKPGPPAGP----LEINGLTAE------KCSLSWGRPQ 26835
Query: 125 PWASWDKDGSII----TPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAE 179
D D I+ T T+ E E M ++ ++ + I+R+T N+ G E
Sbjct: 26836 EDGGADIDYYIVEKRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGE 26894
Score = 30.7 bits (66), Expect = 4.2
Identities = 15/59 (25%), Positives = 27/59 (45%), Gaps = 1/59 (1%)
Query: 7 DTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
D V +C+++ D ++WF + I+ + D L +K+ D G YTC+
Sbjct: 12960 DEVILQCEIS-KADAPVKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTCD 13017
Score = 30.7 bits (66), Expect = 4.2
Identities = 20/68 (29%), Positives = 28/68 (41%), Gaps = 6/68 (8%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCA--DFESSYDDGTARLKIKQVTAEDEGTYT 63
G ++ + G P P+++W IRD A D SS+ L + V D G YT
Sbjct: 23884 GGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSF----TSLVLDNVNRYDSGKYT 23939
Query: 64 CEASNCLG 71
N G
Sbjct: 23940 LTLENSSG 23947
Score = 30.7 bits (66), Expect = 4.2
Identities = 16/75 (21%), Positives = 31/75 (41%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G ++ E ++G P P I W ++ + L IK+ +D G Y
Sbjct: 24171 GQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGIT 24230
Query: 66 ASNCLGKAKSNACLV 80
+N +G+ ++ +V
Sbjct: 24231 VANVVGQKTASIEIV 24245
Score = 30.3 bits (65), Expect = 5.5
Identities = 22/84 (26%), Positives = 37/84 (44%), Gaps = 6/84 (7%)
Query: 109 EGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYR 168
E + V +C + +P W KDG I PS +K + R+L + + D+G Y
Sbjct: 12958 EKDEVILQCEISKADAP-VKWFKDGKEIKPSKNAVIKADGK-KRMLILKKALKSDIGQYT 13015
Query: 169 ITVENELGRAEASARLEVITRSGK 192
+ G + S +L++ R K
Sbjct: 13016 C----DCGTDKTSGKLDIEDREIK 13035
Score = 30.3 bits (65), Expect = 5.5
Identities = 20/71 (28%), Positives = 29/71 (40%), Gaps = 2/71 (2%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRD-CADFESSYDDGTARLKIKQVTAEDEGTYTC 64
G+T E + G P PD+ W + + + A E L +K D G Y
Sbjct: 25649 GETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYIL 25708
Query: 65 EASNCLGKAKS 75
+ SN +G KS
Sbjct: 25709 KLSN-VGGTKS 25718
Score = 30.3 bits (65), Expect = 5.5
Identities = 17/64 (26%), Positives = 26/64 (40%), Gaps = 2/64 (3%)
Query: 8 TVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEAS 67
T+ + G P+P+++W ++ D A E + L I VT D G Y
Sbjct: 26051 TLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVT--SSFTMLVIDNVTRFDSGRYNLTLE 26108
Query: 68 NCLG 71
N G
Sbjct: 26109 NNSG 26112
Score = 29.9 bits (64), Expect = 7.3
Identities = 28/99 (28%), Positives = 38/99 (38%), Gaps = 12/99 (12%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCAD---FESSYD----DGTARLKIKQVTAE 57
+G V ++ G P P + WF D + +++ + D T L I Q
Sbjct: 17057 EGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRS 17116
Query: 58 DEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAP 96
D G YT A N LG A L V L PG + P
Sbjct: 17117 DTGLYTITAVNNLGTASKEMRLNV-----LGRPGPPVGP 17150
Score = 29.9 bits (64), Expect = 7.3
Identities = 17/65 (26%), Positives = 22/65 (33%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G V E G P P I W +++ S + L IK E G YT
Sbjct: 28505 GHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVI 28564
Query: 66 ASNCL 70
N +
Sbjct: 28565 LDNAV 28569
Score = 29.5 bits (63), Expect = 9.6
Identities = 18/77 (23%), Positives = 30/77 (38%), Gaps = 1/77 (1%)
Query: 113 VTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVE 172
+T G P P A+W ++ R+ +K ++ I D GIY + +E
Sbjct: 14339 ITILVPSTGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELV-ISPSERSDKGIYTLKLE 14397
Query: 173 NELGRAEASARLEVITR 189
N + + VI R
Sbjct: 14398 NRVKTISGEIDVNVIAR 14414
Score = 29.5 bits (63), Expect = 9.6
Identities = 16/70 (22%), Positives = 29/70 (41%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G +V+ ++G P P I W+ + ++ A A + IK + G Y +
Sbjct: 27814 GTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELK 27873
Query: 66 ASNCLGKAKS 75
N +G A +
Sbjct: 27874 LRNAMGSASA 27883
>AM231061-1|CAJ76912.1| 1960|Homo sapiens obscurin isoform B
protein.
Length = 1960
Score = 92.3 bits (219), Expect = 1e-18
Identities = 56/183 (30%), Positives = 86/183 (46%), Gaps = 13/183 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIR-DCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
G+TV+ C+VTG P P I W+ + ++ D DG+ L + +T D G Y C
Sbjct: 20 GETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQYMC 79
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
A++ G + ++V Q+ P F EGE+ F C ++G P
Sbjct: 80 FAASAAGNCSTLGKILV-----------QVPPRFVNKVRASPFVEGEDAQFTCTIEGAPY 128
Query: 125 PWASWDKDGSIITPSARI-TVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
P W KDG+++T + T+ E + +L I S ED+G+Y + N LG A ASA
Sbjct: 129 PQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAE 188
Query: 184 LEV 186
L +
Sbjct: 189 LRI 191
Score = 60.1 bits (139), Expect = 6e-09
Identities = 31/95 (32%), Positives = 49/95 (51%)
Query: 95 APTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRIL 154
APTF ++ V G++VT C V P+ A+W KDG+ + S+R+ + + ++L
Sbjct: 1454 APTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLL 1513
Query: 155 EIDEVSIEDVGIYRITVENELGRAEASARLEVITR 189
I V ED+G+Y +V N LG + L R
Sbjct: 1514 TILVVVAEDLGVYTCSVSNALGTVTTTGVLRKAER 1548
Score = 49.6 bits (113), Expect = 8e-06
Identities = 23/76 (30%), Positives = 37/76 (48%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G T +FE + G+P P + W+ + + D + T L ++ V ++D G YTC
Sbjct: 363 GGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLVLRHVASKDAGVYTCL 422
Query: 66 ASNCLGKAKSNACLVV 81
A N G+ A L+V
Sbjct: 423 AQNTGGQVLCKAELLV 438
Score = 48.8 bits (111), Expect = 1e-05
Identities = 25/75 (33%), Positives = 38/75 (50%), Gaps = 2/75 (2%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFE--SSYDDGTARLKIKQVTAEDEGTY 62
+G+ +F C + G P P IRW+ ++ F+ S G L I+ + ED G Y
Sbjct: 113 EGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLY 172
Query: 63 TCEASNCLGKAKSNA 77
CE N LG A+++A
Sbjct: 173 ECELVNRLGSARASA 187
Score = 41.5 bits (93), Expect = 0.002
Identities = 21/80 (26%), Positives = 40/80 (50%), Gaps = 1/80 (1%)
Query: 108 EEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIY 167
+ G F+ ++G+P P +W KD + S R++ +++E L + V+ +D G+Y
Sbjct: 361 QTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLS-QQQEGTTYSLVLRHVASKDAGVY 419
Query: 168 RITVENELGRAEASARLEVI 187
+N G+ A L V+
Sbjct: 420 TCLAQNTGGQVLCKAELLVL 439
Score = 36.7 bits (81), Expect = 0.063
Identities = 22/79 (27%), Positives = 31/79 (39%)
Query: 108 EEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIY 167
E GE V C V G P P SW KDG + + E + L +D ++ D G Y
Sbjct: 18 ELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQY 77
Query: 168 RITVENELGRAEASARLEV 186
+ G ++ V
Sbjct: 78 MCFAASAAGNCSTLGKILV 96
Score = 35.9 bits (79), Expect = 0.11
Identities = 23/75 (30%), Positives = 29/75 (38%), Gaps = 1/75 (1%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCAD-FESSYDDGTARLKIKQVTAEDEGTYTC 64
G +V CQV+ P W + + S+ L I V AED G YTC
Sbjct: 1469 GQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLLTILVVVAEDLGVYTC 1528
Query: 65 EASNCLGKAKSNACL 79
SN LG + L
Sbjct: 1529 SVSNALGTVTTTGVL 1543
>AL670729-4|CAH71670.2| 2582|Homo sapiens obscurin, cytoskeletal
calmodulin and titin-interacting RhoGEF protein.
Length = 2582
Score = 92.3 bits (219), Expect = 1e-18
Identities = 56/183 (30%), Positives = 86/183 (46%), Gaps = 13/183 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIR-DCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
G+TV+ C+VTG P P I W+ + ++ D DG+ L + +T D G Y C
Sbjct: 644 GETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQYMC 703
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
A++ G + ++V Q+ P F EGE+ F C ++G P
Sbjct: 704 FAASAAGNCSTLGKILV-----------QVPPRFVNKVRASPFVEGEDAQFTCTIEGAPY 752
Query: 125 PWASWDKDGSIITPSARI-TVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
P W KDG+++T + T+ E + +L I S ED+G+Y + N LG A ASA
Sbjct: 753 PQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAE 812
Query: 184 LEV 186
L +
Sbjct: 813 LRI 815
Score = 60.1 bits (139), Expect = 6e-09
Identities = 31/95 (32%), Positives = 49/95 (51%)
Query: 95 APTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRIL 154
APTF ++ V G++VT C V P+ A+W KDG+ + S+R+ + + ++L
Sbjct: 2078 APTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLL 2137
Query: 155 EIDEVSIEDVGIYRITVENELGRAEASARLEVITR 189
I V ED+G+Y +V N LG + L R
Sbjct: 2138 TILVVVAEDLGVYTCSVSNALGTVTTTGVLRKAER 2172
Score = 49.6 bits (113), Expect = 8e-06
Identities = 23/76 (30%), Positives = 37/76 (48%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G T +FE + G+P P + W+ + + D + T L ++ V ++D G YTC
Sbjct: 987 GGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLVLRHVASKDAGVYTCL 1046
Query: 66 ASNCLGKAKSNACLVV 81
A N G+ A L+V
Sbjct: 1047 AQNTGGQVLCKAELLV 1062
Score = 48.8 bits (111), Expect = 1e-05
Identities = 25/75 (33%), Positives = 38/75 (50%), Gaps = 2/75 (2%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFE--SSYDDGTARLKIKQVTAEDEGTY 62
+G+ +F C + G P P IRW+ ++ F+ S G L I+ + ED G Y
Sbjct: 737 EGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLY 796
Query: 63 TCEASNCLGKAKSNA 77
CE N LG A+++A
Sbjct: 797 ECELVNRLGSARASA 811
Score = 41.5 bits (93), Expect = 0.002
Identities = 21/80 (26%), Positives = 40/80 (50%), Gaps = 1/80 (1%)
Query: 108 EEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIY 167
+ G F+ ++G+P P +W KD + S R++ +++E L + V+ +D G+Y
Sbjct: 985 QTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLS-QQQEGTTYSLVLRHVASKDAGVY 1043
Query: 168 RITVENELGRAEASARLEVI 187
+N G+ A L V+
Sbjct: 1044 TCLAQNTGGQVLCKAELLVL 1063
Score = 36.7 bits (81), Expect = 0.063
Identities = 22/79 (27%), Positives = 31/79 (39%)
Query: 108 EEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIY 167
E GE V C V G P P SW KDG + + E + L +D ++ D G Y
Sbjct: 642 ELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQY 701
Query: 168 RITVENELGRAEASARLEV 186
+ G ++ V
Sbjct: 702 MCFAASAAGNCSTLGKILV 720
Score = 35.9 bits (79), Expect = 0.11
Identities = 23/75 (30%), Positives = 29/75 (38%), Gaps = 1/75 (1%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCAD-FESSYDDGTARLKIKQVTAEDEGTYTC 64
G +V CQV+ P W + + S+ L I V AED G YTC
Sbjct: 2093 GQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLLTILVVVAEDLGVYTC 2152
Query: 65 EASNCLGKAKSNACL 79
SN LG + L
Sbjct: 2153 SVSNALGTVTTTGVL 2167
Score = 34.3 bits (75), Expect = 0.34
Identities = 24/80 (30%), Positives = 36/80 (45%), Gaps = 6/80 (7%)
Query: 8 TVEFECQVTGNPDPDIRWFHY-AE-----VIRDCADFESSYDDGTARLKIKQVTAEDEGT 61
++ F +V G P P + W AE + D + + L + V + +GT
Sbjct: 2 SITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLDVGRQHQGT 61
Query: 62 YTCEASNCLGKAKSNACLVV 81
YTC ASN G+A +A L V
Sbjct: 62 YTCIASNAAGQALCSASLHV 81
>AL353593-4|CAM27610.1| 2582|Homo sapiens obscurin, cytoskeletal
calmodulin and titin-interacting RhoGEF protein.
Length = 2582
Score = 92.3 bits (219), Expect = 1e-18
Identities = 56/183 (30%), Positives = 86/183 (46%), Gaps = 13/183 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIR-DCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
G+TV+ C+VTG P P I W+ + ++ D DG+ L + +T D G Y C
Sbjct: 644 GETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQYMC 703
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
A++ G + ++V Q+ P F EGE+ F C ++G P
Sbjct: 704 FAASAAGNCSTLGKILV-----------QVPPRFVNKVRASPFVEGEDAQFTCTIEGAPY 752
Query: 125 PWASWDKDGSIITPSARI-TVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
P W KDG+++T + T+ E + +L I S ED+G+Y + N LG A ASA
Sbjct: 753 PQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAE 812
Query: 184 LEV 186
L +
Sbjct: 813 LRI 815
Score = 60.1 bits (139), Expect = 6e-09
Identities = 31/95 (32%), Positives = 49/95 (51%)
Query: 95 APTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRIL 154
APTF ++ V G++VT C V P+ A+W KDG+ + S+R+ + + ++L
Sbjct: 2078 APTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLL 2137
Query: 155 EIDEVSIEDVGIYRITVENELGRAEASARLEVITR 189
I V ED+G+Y +V N LG + L R
Sbjct: 2138 TILVVVAEDLGVYTCSVSNALGTVTTTGVLRKAER 2172
Score = 49.6 bits (113), Expect = 8e-06
Identities = 23/76 (30%), Positives = 37/76 (48%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G T +FE + G+P P + W+ + + D + T L ++ V ++D G YTC
Sbjct: 987 GGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLVLRHVASKDAGVYTCL 1046
Query: 66 ASNCLGKAKSNACLVV 81
A N G+ A L+V
Sbjct: 1047 AQNTGGQVLCKAELLV 1062
Score = 48.8 bits (111), Expect = 1e-05
Identities = 25/75 (33%), Positives = 38/75 (50%), Gaps = 2/75 (2%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFE--SSYDDGTARLKIKQVTAEDEGTY 62
+G+ +F C + G P P IRW+ ++ F+ S G L I+ + ED G Y
Sbjct: 737 EGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLY 796
Query: 63 TCEASNCLGKAKSNA 77
CE N LG A+++A
Sbjct: 797 ECELVNRLGSARASA 811
Score = 41.5 bits (93), Expect = 0.002
Identities = 21/80 (26%), Positives = 40/80 (50%), Gaps = 1/80 (1%)
Query: 108 EEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIY 167
+ G F+ ++G+P P +W KD + S R++ +++E L + V+ +D G+Y
Sbjct: 985 QTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLS-QQQEGTTYSLVLRHVASKDAGVY 1043
Query: 168 RITVENELGRAEASARLEVI 187
+N G+ A L V+
Sbjct: 1044 TCLAQNTGGQVLCKAELLVL 1063
Score = 36.7 bits (81), Expect = 0.063
Identities = 22/79 (27%), Positives = 31/79 (39%)
Query: 108 EEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIY 167
E GE V C V G P P SW KDG + + E + L +D ++ D G Y
Sbjct: 642 ELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQY 701
Query: 168 RITVENELGRAEASARLEV 186
+ G ++ V
Sbjct: 702 MCFAASAAGNCSTLGKILV 720
Score = 35.9 bits (79), Expect = 0.11
Identities = 23/75 (30%), Positives = 29/75 (38%), Gaps = 1/75 (1%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCAD-FESSYDDGTARLKIKQVTAEDEGTYTC 64
G +V CQV+ P W + + S+ L I V AED G YTC
Sbjct: 2093 GQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLLTILVVVAEDLGVYTC 2152
Query: 65 EASNCLGKAKSNACL 79
SN LG + L
Sbjct: 2153 SVSNALGTVTTTGVL 2167
Score = 34.3 bits (75), Expect = 0.34
Identities = 24/80 (30%), Positives = 36/80 (45%), Gaps = 6/80 (7%)
Query: 8 TVEFECQVTGNPDPDIRWFHY-AE-----VIRDCADFESSYDDGTARLKIKQVTAEDEGT 61
++ F +V G P P + W AE + D + + L + V + +GT
Sbjct: 2 SITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLDVGRQHQGT 61
Query: 62 YTCEASNCLGKAKSNACLVV 81
YTC ASN G+A +A L V
Sbjct: 62 YTCIASNAAGQALCSASLHV 81
>AJ314908-1|CAC85755.1| 1020|Homo sapiens obscurin protein.
Length = 1020
Score = 92.3 bits (219), Expect = 1e-18
Identities = 56/183 (30%), Positives = 86/183 (46%), Gaps = 13/183 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIR-DCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
G+TV+ C+VTG P P I W+ + ++ D DG+ L + +T D G Y C
Sbjct: 428 GETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQYMC 487
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
A++ G + ++V Q+ P F EGE+ F C ++G P
Sbjct: 488 FAASAAGNCSTLGKILV-----------QVPPRFVNKVRASPFVEGEDAQFTCTIEGAPY 536
Query: 125 PWASWDKDGSIITPSARI-TVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
P W KDG+++T + T+ E + +L I S ED+G+Y + N LG A ASA
Sbjct: 537 PQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAE 596
Query: 184 LEV 186
L +
Sbjct: 597 LRI 599
Score = 48.8 bits (111), Expect = 1e-05
Identities = 25/75 (33%), Positives = 38/75 (50%), Gaps = 2/75 (2%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFE--SSYDDGTARLKIKQVTAEDEGTY 62
+G+ +F C + G P P IRW+ ++ F+ S G L I+ + ED G Y
Sbjct: 521 EGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLY 580
Query: 63 TCEASNCLGKAKSNA 77
CE N LG A+++A
Sbjct: 581 ECELVNRLGSARASA 595
Score = 36.7 bits (81), Expect = 0.063
Identities = 22/79 (27%), Positives = 31/79 (39%)
Query: 108 EEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIY 167
E GE V C V G P P SW KDG + + E + L +D ++ D G Y
Sbjct: 426 ELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQY 485
Query: 168 RITVENELGRAEASARLEV 186
+ G ++ V
Sbjct: 486 MCFAASAAGNCSTLGKILV 504
>AB046859-1|BAB13465.2| 2584|Homo sapiens KIAA1639 protein protein.
Length = 2584
Score = 92.3 bits (219), Expect = 1e-18
Identities = 56/183 (30%), Positives = 86/183 (46%), Gaps = 13/183 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIR-DCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
G+TV+ C+VTG P P I W+ + ++ D DG+ L + +T D G Y C
Sbjct: 644 GETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQYMC 703
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
A++ G + ++V Q+ P F EGE+ F C ++G P
Sbjct: 704 FAASAAGNCSTLGKILV-----------QVPPRFVNKVRASPFVEGEDAQFTCTIEGAPY 752
Query: 125 PWASWDKDGSIITPSARI-TVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
P W KDG+++T + T+ E + +L I S ED+G+Y + N LG A ASA
Sbjct: 753 PQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAE 812
Query: 184 LEV 186
L +
Sbjct: 813 LRI 815
Score = 60.1 bits (139), Expect = 6e-09
Identities = 31/95 (32%), Positives = 49/95 (51%)
Query: 95 APTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRIL 154
APTF ++ V G++VT C V P+ A+W KDG+ + S+R+ + + ++L
Sbjct: 2078 APTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLL 2137
Query: 155 EIDEVSIEDVGIYRITVENELGRAEASARLEVITR 189
I V ED+G+Y +V N LG + L R
Sbjct: 2138 TILVVVAEDLGVYTCSVSNALGTVTTTGVLRKAER 2172
Score = 49.6 bits (113), Expect = 8e-06
Identities = 23/76 (30%), Positives = 37/76 (48%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G T +FE + G+P P + W+ + + D + T L ++ V ++D G YTC
Sbjct: 987 GGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLVLRHVASKDAGVYTCL 1046
Query: 66 ASNCLGKAKSNACLVV 81
A N G+ A L+V
Sbjct: 1047 AQNTGGQVLCKAELLV 1062
Score = 48.8 bits (111), Expect = 1e-05
Identities = 25/75 (33%), Positives = 38/75 (50%), Gaps = 2/75 (2%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFE--SSYDDGTARLKIKQVTAEDEGTY 62
+G+ +F C + G P P IRW+ ++ F+ S G L I+ + ED G Y
Sbjct: 737 EGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLY 796
Query: 63 TCEASNCLGKAKSNA 77
CE N LG A+++A
Sbjct: 797 ECELVNRLGSARASA 811
Score = 41.5 bits (93), Expect = 0.002
Identities = 21/80 (26%), Positives = 40/80 (50%), Gaps = 1/80 (1%)
Query: 108 EEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIY 167
+ G F+ ++G+P P +W KD + S R++ +++E L + V+ +D G+Y
Sbjct: 985 QTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLS-QQQEGTTYSLVLRHVASKDAGVY 1043
Query: 168 RITVENELGRAEASARLEVI 187
+N G+ A L V+
Sbjct: 1044 TCLAQNTGGQVLCKAELLVL 1063
Score = 36.7 bits (81), Expect = 0.063
Identities = 22/79 (27%), Positives = 31/79 (39%)
Query: 108 EEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIY 167
E GE V C V G P P SW KDG + + E + L +D ++ D G Y
Sbjct: 642 ELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQY 701
Query: 168 RITVENELGRAEASARLEV 186
+ G ++ V
Sbjct: 702 MCFAASAAGNCSTLGKILV 720
Score = 35.9 bits (79), Expect = 0.11
Identities = 23/75 (30%), Positives = 29/75 (38%), Gaps = 1/75 (1%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCAD-FESSYDDGTARLKIKQVTAEDEGTYTC 64
G +V CQV+ P W + + S+ L I V AED G YTC
Sbjct: 2093 GQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLLTILVVVAEDLGVYTC 2152
Query: 65 EASNCLGKAKSNACL 79
SN LG + L
Sbjct: 2153 SVSNALGTVTTTGVL 2167
Score = 33.1 bits (72), Expect = 0.78
Identities = 24/80 (30%), Positives = 36/80 (45%), Gaps = 6/80 (7%)
Query: 8 TVEFECQVTGNPDPDIRWFHY-AE-----VIRDCADFESSYDDGTARLKIKQVTAEDEGT 61
++ F +V G P P + W AE + D + + L + V + +GT
Sbjct: 2 SITFFVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLDVGRQHQGT 61
Query: 62 YTCEASNCLGKAKSNACLVV 81
YTC ASN G+A +A L V
Sbjct: 62 YTCIASNAAGQALCSASLHV 81
>DQ533874-1|ABF83431.1| 1378|Homo sapiens ROBO2 isoform b protein.
Length = 1378
Score = 90.2 bits (214), Expect = 5e-18
Identities = 61/185 (32%), Positives = 87/185 (47%), Gaps = 21/185 (11%)
Query: 7 DTVEFECQVTGNPDPDIRWFHY-AEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
+ VEF CQV G+P P +RW A++ R D + Y L+IK+ + DEGTY C
Sbjct: 240 EAVEFRCQVQGDPQPTVRWKKDDADLPRGRYDIKDDYT-----LRIKKTMSTDEGTYMCI 294
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A N +GK +++A L V + P F P +++V +G VTF C KGNP P
Sbjct: 295 AENRVGKMEASATLTV-----------RAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQP 343
Query: 126 WASWDKDGS--IITPSARITVKEKEEIMRI--LEIDEVSIEDVGIYRITVENELGRAEAS 181
W K+GS ++ P+ + + L I + D G Y G A
Sbjct: 344 AVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAK 403
Query: 182 ARLEV 186
A+LEV
Sbjct: 404 AQLEV 408
Score = 81.0 bits (191), Expect = 3e-15
Identities = 59/182 (32%), Positives = 81/182 (44%), Gaps = 19/182 (10%)
Query: 6 GDTVEFECQVT-GNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
G+ ECQ G+P+P I W + +R D E +L I D G YTC
Sbjct: 147 GEPAILECQPPRGHPEPTIYW--KKDKVR-IDDKEERISIRGGKLMISNTRKSDAGMYTC 203
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
+N +G+ S+ + R PTF P N+VV E E V F+C V+G+P
Sbjct: 204 VGTNMVGERDSDPAELTVFER----------PTFLRRPINQVVLEEEAVEFRCQVQGDPQ 253
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
P W KD + + P R +K+ L I + D G Y EN +G+ EASA L
Sbjct: 254 PTVRWKKDDADL-PRGRYDIKDD----YTLRIKKTMSTDEGTYMCIAENRVGKMEASATL 308
Query: 185 EV 186
V
Sbjct: 309 TV 310
Score = 56.0 bits (129), Expect = 1e-07
Identities = 53/192 (27%), Positives = 73/192 (38%), Gaps = 16/192 (8%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAE---VIRDCADFESSYDD--GTARLKIKQVTAEDEG 60
G TV F C+ GNP P + W + + +S T L I + D G
Sbjct: 328 GRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAG 387
Query: 61 TYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVK 120
Y C+A G + A L V P P P N+ + KC
Sbjct: 388 YYICQALTVAGSILAKAQLEVTDVLTDRPP-----PIILQGPANQTLAVDGTALLKCKAT 442
Query: 121 GNPSPWASWDKDG-SIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAE 179
G+P P SW K+G + R T++E+ L+I + I D G Y + G
Sbjct: 443 GDPLPVISWLKEGFTFPGRDPRATIQEQ----GTLQIKNLRISDTGTYTCVATSSSGETS 498
Query: 180 ASARLEVITRSG 191
SA L+V T SG
Sbjct: 499 WSAVLDV-TESG 509
Score = 52.8 bits (121), Expect = 9e-07
Identities = 56/198 (28%), Positives = 80/198 (40%), Gaps = 32/198 (16%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSY----DDGTA---RLKIKQVTAED 58
G+ C+ G P P I W+ E + D S+ G+ R+ + + D
Sbjct: 45 GEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKPD 104
Query: 59 EGTYTCEASNCLGKAKS-NACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKC 117
EG+Y C A N LG+A S NA L V R F P + VV GE +C
Sbjct: 105 EGSYVCVARNYLGEAVSRNASLEVALLR----------DDFRQNPTDVVVAAGEPAILEC 154
Query: 118 -AVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRI----LEIDEVSIEDVGIYRITVE 172
+G+P P W KD ++ + +KEE + I L I D G+Y
Sbjct: 155 QPPRGHPEPTIYWKKD--------KVRIDDKEERISIRGGKLMISNTRKSDAGMYTCVGT 206
Query: 173 NELGRAEAS-ARLEVITR 189
N +G ++ A L V R
Sbjct: 207 NMVGERDSDPAELTVFER 224
Score = 41.9 bits (94), Expect = 0.002
Identities = 27/80 (33%), Positives = 39/80 (48%), Gaps = 3/80 (3%)
Query: 2 LSCDGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGT 61
L+ DG T +C+ TG+P P I W + + GT L+IK + D GT
Sbjct: 429 LAVDG-TALLKCKATGDPLPVISWLKEGFTFPGRDPRATIQEQGT--LQIKNLRISDTGT 485
Query: 62 YTCEASNCLGKAKSNACLVV 81
YTC A++ G+ +A L V
Sbjct: 486 YTCVATSSSGETSWSAVLDV 505
Score = 38.3 bits (85), Expect = 0.021
Identities = 28/98 (28%), Positives = 39/98 (39%), Gaps = 7/98 (7%)
Query: 96 PTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITP------SARITVKEKEE 149
P +P + +V +GE T C +G P+P W KDG + S R+ +
Sbjct: 31 PRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSL 90
Query: 150 IMRILEIDEVSIEDVGIYRITVENELGRA-EASARLEV 186
+ S D G Y N LG A +A LEV
Sbjct: 91 FFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEV 128
>DQ533873-1|ABF83430.1| 1394|Homo sapiens ROBO2 isoform a protein.
Length = 1394
Score = 90.2 bits (214), Expect = 5e-18
Identities = 61/185 (32%), Positives = 87/185 (47%), Gaps = 21/185 (11%)
Query: 7 DTVEFECQVTGNPDPDIRWFHY-AEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
+ VEF CQV G+P P +RW A++ R D + Y L+IK+ + DEGTY C
Sbjct: 256 EAVEFRCQVQGDPQPTVRWKKDDADLPRGRYDIKDDYT-----LRIKKTMSTDEGTYMCI 310
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A N +GK +++A L V + P F P +++V +G VTF C KGNP P
Sbjct: 311 AENRVGKMEASATLTV-----------RAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQP 359
Query: 126 WASWDKDGS--IITPSARITVKEKEEIMRI--LEIDEVSIEDVGIYRITVENELGRAEAS 181
W K+GS ++ P+ + + L I + D G Y G A
Sbjct: 360 AVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAK 419
Query: 182 ARLEV 186
A+LEV
Sbjct: 420 AQLEV 424
Score = 81.0 bits (191), Expect = 3e-15
Identities = 59/182 (32%), Positives = 81/182 (44%), Gaps = 19/182 (10%)
Query: 6 GDTVEFECQVT-GNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
G+ ECQ G+P+P I W + +R D E +L I D G YTC
Sbjct: 163 GEPAILECQPPRGHPEPTIYW--KKDKVR-IDDKEERISIRGGKLMISNTRKSDAGMYTC 219
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
+N +G+ S+ + R PTF P N+VV E E V F+C V+G+P
Sbjct: 220 VGTNMVGERDSDPAELTVFER----------PTFLRRPINQVVLEEEAVEFRCQVQGDPQ 269
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
P W KD + + P R +K+ L I + D G Y EN +G+ EASA L
Sbjct: 270 PTVRWKKDDADL-PRGRYDIKDD----YTLRIKKTMSTDEGTYMCIAENRVGKMEASATL 324
Query: 185 EV 186
V
Sbjct: 325 TV 326
Score = 56.0 bits (129), Expect = 1e-07
Identities = 53/192 (27%), Positives = 73/192 (38%), Gaps = 16/192 (8%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAE---VIRDCADFESSYDD--GTARLKIKQVTAEDEG 60
G TV F C+ GNP P + W + + +S T L I + D G
Sbjct: 344 GRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAG 403
Query: 61 TYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVK 120
Y C+A G + A L V P P P N+ + KC
Sbjct: 404 YYICQALTVAGSILAKAQLEVTDVLTDRPP-----PIILQGPANQTLAVDGTALLKCKAT 458
Query: 121 GNPSPWASWDKDG-SIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAE 179
G+P P SW K+G + R T++E+ L+I + I D G Y + G
Sbjct: 459 GDPLPVISWLKEGFTFPGRDPRATIQEQ----GTLQIKNLRISDTGTYTCVATSSSGETS 514
Query: 180 ASARLEVITRSG 191
SA L+V T SG
Sbjct: 515 WSAVLDV-TESG 525
Score = 52.8 bits (121), Expect = 9e-07
Identities = 56/198 (28%), Positives = 80/198 (40%), Gaps = 32/198 (16%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSY----DDGTA---RLKIKQVTAED 58
G+ C+ G P P I W+ E + D S+ G+ R+ + + D
Sbjct: 61 GEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKPD 120
Query: 59 EGTYTCEASNCLGKAKS-NACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKC 117
EG+Y C A N LG+A S NA L V R F P + VV GE +C
Sbjct: 121 EGSYVCVARNYLGEAVSRNASLEVALLR----------DDFRQNPTDVVVAAGEPAILEC 170
Query: 118 -AVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRI----LEIDEVSIEDVGIYRITVE 172
+G+P P W KD ++ + +KEE + I L I D G+Y
Sbjct: 171 QPPRGHPEPTIYWKKD--------KVRIDDKEERISIRGGKLMISNTRKSDAGMYTCVGT 222
Query: 173 NELGRAEAS-ARLEVITR 189
N +G ++ A L V R
Sbjct: 223 NMVGERDSDPAELTVFER 240
Score = 41.9 bits (94), Expect = 0.002
Identities = 27/80 (33%), Positives = 39/80 (48%), Gaps = 3/80 (3%)
Query: 2 LSCDGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGT 61
L+ DG T +C+ TG+P P I W + + GT L+IK + D GT
Sbjct: 445 LAVDG-TALLKCKATGDPLPVISWLKEGFTFPGRDPRATIQEQGT--LQIKNLRISDTGT 501
Query: 62 YTCEASNCLGKAKSNACLVV 81
YTC A++ G+ +A L V
Sbjct: 502 YTCVATSSSGETSWSAVLDV 521
Score = 38.3 bits (85), Expect = 0.021
Identities = 28/98 (28%), Positives = 39/98 (39%), Gaps = 7/98 (7%)
Query: 96 PTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITP------SARITVKEKEE 149
P +P + +V +GE T C +G P+P W KDG + S R+ +
Sbjct: 47 PRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSL 106
Query: 150 IMRILEIDEVSIEDVGIYRITVENELGRA-EASARLEV 186
+ S D G Y N LG A +A LEV
Sbjct: 107 FFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEV 144
>AB046788-1|BAB13394.1| 1380|Homo sapiens KIAA1568 protein protein.
Length = 1380
Score = 90.2 bits (214), Expect = 5e-18
Identities = 61/185 (32%), Positives = 87/185 (47%), Gaps = 21/185 (11%)
Query: 7 DTVEFECQVTGNPDPDIRWFHY-AEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
+ VEF CQV G+P P +RW A++ R D + Y L+IK+ + DEGTY C
Sbjct: 242 EAVEFRCQVQGDPQPTVRWKKDDADLPRGRYDIKDDYT-----LRIKKTMSTDEGTYMCI 296
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A N +GK +++A L V + P F P +++V +G VTF C KGNP P
Sbjct: 297 AENRVGKMEASATLTV-----------RAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQP 345
Query: 126 WASWDKDGS--IITPSARITVKEKEEIMRI--LEIDEVSIEDVGIYRITVENELGRAEAS 181
W K+GS ++ P+ + + L I + D G Y G A
Sbjct: 346 AVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAK 405
Query: 182 ARLEV 186
A+LEV
Sbjct: 406 AQLEV 410
Score = 81.0 bits (191), Expect = 3e-15
Identities = 59/182 (32%), Positives = 81/182 (44%), Gaps = 19/182 (10%)
Query: 6 GDTVEFECQVT-GNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
G+ ECQ G+P+P I W + +R D E +L I D G YTC
Sbjct: 149 GEPAILECQPPRGHPEPTIYW--KKDKVR-IDDKEERISIRGGKLMISNTRKSDAGMYTC 205
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
+N +G+ S+ + R PTF P N+VV E E V F+C V+G+P
Sbjct: 206 VGTNMVGERDSDPAELTVFER----------PTFLRRPINQVVLEEEAVEFRCQVQGDPQ 255
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
P W KD + + P R +K+ L I + D G Y EN +G+ EASA L
Sbjct: 256 PTVRWKKDDADL-PRGRYDIKDD----YTLRIKKTMSTDEGTYMCIAENRVGKMEASATL 310
Query: 185 EV 186
V
Sbjct: 311 TV 312
Score = 56.0 bits (129), Expect = 1e-07
Identities = 53/192 (27%), Positives = 73/192 (38%), Gaps = 16/192 (8%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAE---VIRDCADFESSYDD--GTARLKIKQVTAEDEG 60
G TV F C+ GNP P + W + + +S T L I + D G
Sbjct: 330 GRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAG 389
Query: 61 TYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVK 120
Y C+A G + A L V P P P N+ + KC
Sbjct: 390 YYICQALTVAGSILAKAQLEVTDVLTDRPP-----PIILQGPANQTLAVDGTALLKCKAT 444
Query: 121 GNPSPWASWDKDG-SIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAE 179
G+P P SW K+G + R T++E+ L+I + I D G Y + G
Sbjct: 445 GDPLPVISWLKEGFTFPGRDPRATIQEQ----GTLQIKNLRISDTGTYTCVATSSSGETS 500
Query: 180 ASARLEVITRSG 191
SA L+V T SG
Sbjct: 501 WSAVLDV-TESG 511
Score = 52.8 bits (121), Expect = 9e-07
Identities = 56/198 (28%), Positives = 80/198 (40%), Gaps = 32/198 (16%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSY----DDGTA---RLKIKQVTAED 58
G+ C+ G P P I W+ E + D S+ G+ R+ + + D
Sbjct: 47 GEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRRSKPD 106
Query: 59 EGTYTCEASNCLGKAKS-NACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKC 117
EG+Y C A N LG+A S NA L V R F P + VV GE +C
Sbjct: 107 EGSYVCVARNYLGEAVSRNASLEVALLR----------DDFRQNPTDVVVAAGEPAILEC 156
Query: 118 -AVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRI----LEIDEVSIEDVGIYRITVE 172
+G+P P W KD ++ + +KEE + I L I D G+Y
Sbjct: 157 QPPRGHPEPTIYWKKD--------KVRIDDKEERISIRGGKLMISNTRKSDAGMYTCVGT 208
Query: 173 NELGRAEAS-ARLEVITR 189
N +G ++ A L V R
Sbjct: 209 NMVGERDSDPAELTVFER 226
Score = 41.9 bits (94), Expect = 0.002
Identities = 27/80 (33%), Positives = 39/80 (48%), Gaps = 3/80 (3%)
Query: 2 LSCDGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGT 61
L+ DG T +C+ TG+P P I W + + GT L+IK + D GT
Sbjct: 431 LAVDG-TALLKCKATGDPLPVISWLKEGFTFPGRDPRATIQEQGT--LQIKNLRISDTGT 487
Query: 62 YTCEASNCLGKAKSNACLVV 81
YTC A++ G+ +A L V
Sbjct: 488 YTCVATSSSGETSWSAVLDV 507
Score = 38.3 bits (85), Expect = 0.021
Identities = 28/98 (28%), Positives = 39/98 (39%), Gaps = 7/98 (7%)
Query: 96 PTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITP------SARITVKEKEE 149
P +P + +V +GE T C +G P+P W KDG + S R+ +
Sbjct: 33 PRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSL 92
Query: 150 IMRILEIDEVSIEDVGIYRITVENELGRA-EASARLEV 186
+ S D G Y N LG A +A LEV
Sbjct: 93 FFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEV 130
>D86983-1|BAA13219.1| 1496|Homo sapiens KIAA0230 protein.
Length = 1496
Score = 87.8 bits (208), Expect = 3e-17
Identities = 60/183 (32%), Positives = 84/183 (45%), Gaps = 18/183 (9%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIR-DCADFESSYDDGTARLKIKQVTAEDEGTYT 63
+G TV+F+C+ GNP P I W + D S GT L+I V D+G Y
Sbjct: 463 EGQTVDFQCEAKGNPPPVIAWTKGGSQLSVDRRHLVLS--SGT--LRISGVALHDQGQYE 518
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
C+A N +G K A L V P ++ P F + P + VE G NV C+ +G P
Sbjct: 519 CQAVNIIGSQKVVAHLTV-------QP--RVTPVFASIPSDTTVEVGANVQLPCSSQGEP 569
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
P +W+KDG +T S + + + L I++V D G Y N +G A S
Sbjct: 570 EPAITWNKDGVQVTESGKFHISPE----GFLTINDVGPADAGRYECVARNTIGSASVSMV 625
Query: 184 LEV 186
L V
Sbjct: 626 LSV 628
Score = 79.0 bits (186), Expect = 1e-14
Identities = 57/179 (31%), Positives = 80/179 (44%), Gaps = 15/179 (8%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSY-DDGTARLKIKQVTAEDEGTYTC 64
G+TV F C+ GNP P+I W + D + DDGT ++ Q T D+G Y C
Sbjct: 277 GNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLDDGTLMIQNTQET--DQGIYQC 334
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
A N G+ K+ + Y SP R PTF P N V GE+VT +C+ G+P
Sbjct: 335 MAKNVAGEVKTQEVTLRY----FGSPAR---PTFVIQPQNTEVLVGESVTLECSATGHPP 387
Query: 125 PWASWDK-DGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASA 182
P SW + D + + R+ + L I V D G Y + N + A+A
Sbjct: 388 PRISWTRGDRTPLPVDPRVNITPSGG----LYIQNVVQGDSGEYACSATNNIDSVHATA 442
Score = 76.6 bits (180), Expect = 6e-14
Identities = 56/184 (30%), Positives = 77/184 (41%), Gaps = 17/184 (9%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G++V EC TG+P P I W + G L I+ V D G Y C
Sbjct: 373 GESVTLECSATGHPPPRISWTRGDRTPLPVDPRVNITPSGG--LYIQNVVQGDSGEYACS 430
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A+N + + A ++V Q P F P ++VV EG+ V F+C KGNP P
Sbjct: 431 ATNNIDSVHATAFIIV-----------QALPQFTVTPQDRVVIEGQTVDFQCEAKGNPPP 479
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
+W K GS ++ R V L I V++ D G Y N +G + A L
Sbjct: 480 VIAWTKGGSQLSVDRRHLVLSS----GTLRISGVALHDQGQYECQAVNIIGSQKVVAHLT 535
Query: 186 VITR 189
V R
Sbjct: 536 VQPR 539
Score = 33.1 bits (72), Expect = 0.78
Identities = 21/86 (24%), Positives = 37/86 (43%), Gaps = 6/86 (6%)
Query: 96 PTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIIT--PSARITVKEKEEIMRI 153
P + P + V G V F C +GNP P W ++ + ++ +R+ + + +M
Sbjct: 263 PRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLDDGTLM-- 320
Query: 154 LEIDEVSIEDVGIYRITVENELGRAE 179
I D GIY+ +N G +
Sbjct: 321 --IQNTQETDQGIYQCMAKNVAGEVK 344
>BC098579-1|AAH98579.1| 722|Homo sapiens PXDN protein protein.
Length = 722
Score = 87.8 bits (208), Expect = 3e-17
Identities = 60/183 (32%), Positives = 84/183 (45%), Gaps = 18/183 (9%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIR-DCADFESSYDDGTARLKIKQVTAEDEGTYT 63
+G TV+F+C+ GNP P I W + D S GT L+I V D+G Y
Sbjct: 441 EGQTVDFQCEAKGNPPPVIAWTKGGSQLSVDRRHLVLS--SGT--LRISGVALHDQGQYE 496
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
C+A N +G K A L V P ++ P F + P + VE G NV C+ +G P
Sbjct: 497 CQAVNIIGSQKVVAHLTV-------QP--RVTPVFASIPSDTTVEVGANVQLPCSSQGEP 547
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
P +W+KDG +T S + + + L I++V D G Y N +G A S
Sbjct: 548 EPAITWNKDGVQVTESGKFHISPE----GFLTINDVGPADAGRYECVARNTIGSASVSMV 603
Query: 184 LEV 186
L V
Sbjct: 604 LSV 606
Score = 79.0 bits (186), Expect = 1e-14
Identities = 57/179 (31%), Positives = 80/179 (44%), Gaps = 15/179 (8%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSY-DDGTARLKIKQVTAEDEGTYTC 64
G+TV F C+ GNP P+I W + D + DDGT ++ Q T D+G Y C
Sbjct: 255 GNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLDDGTLMIQNTQET--DQGIYQC 312
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
A N G+ K+ + Y SP R PTF P N V GE+VT +C+ G+P
Sbjct: 313 MAKNVAGEVKTQEVTLRY----FGSPAR---PTFVIQPQNTEVLVGESVTLECSATGHPP 365
Query: 125 PWASWDK-DGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASA 182
P SW + D + + R+ + L I V D G Y + N + A+A
Sbjct: 366 PRISWTRGDRTPLPVDPRVNITPSGG----LYIQNVVQGDSGEYACSATNNIDSVHATA 420
Score = 76.6 bits (180), Expect = 6e-14
Identities = 56/184 (30%), Positives = 77/184 (41%), Gaps = 17/184 (9%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G++V EC TG+P P I W + G L I+ V D G Y C
Sbjct: 351 GESVTLECSATGHPPPRISWTRGDRTPLPVDPRVNITPSGG--LYIQNVVQGDSGEYACS 408
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A+N + + A ++V Q P F P ++VV EG+ V F+C KGNP P
Sbjct: 409 ATNNIDSVHATAFIIV-----------QALPQFTVTPQDRVVIEGQTVDFQCEAKGNPPP 457
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
+W K GS ++ R V L I V++ D G Y N +G + A L
Sbjct: 458 VIAWTKGGSQLSVDRRHLVLSS----GTLRISGVALHDQGQYECQAVNIIGSQKVVAHLT 513
Query: 186 VITR 189
V R
Sbjct: 514 VQPR 517
Score = 33.1 bits (72), Expect = 0.78
Identities = 21/86 (24%), Positives = 37/86 (43%), Gaps = 6/86 (6%)
Query: 96 PTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIIT--PSARITVKEKEEIMRI 153
P + P + V G V F C +GNP P W ++ + ++ +R+ + + +M
Sbjct: 241 PRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLDDGTLM-- 298
Query: 154 LEIDEVSIEDVGIYRITVENELGRAE 179
I D GIY+ +N G +
Sbjct: 299 --IQNTQETDQGIYQCMAKNVAGEVK 322
>AF200348-1|AAF06354.1| 1496|Homo sapiens melanoma-associated
antigen MG50 protein.
Length = 1496
Score = 87.8 bits (208), Expect = 3e-17
Identities = 60/183 (32%), Positives = 84/183 (45%), Gaps = 18/183 (9%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIR-DCADFESSYDDGTARLKIKQVTAEDEGTYT 63
+G TV+F+C+ GNP P I W + D S GT L+I V D+G Y
Sbjct: 463 EGQTVDFQCEAKGNPPPVIAWTKGGSQLSVDRRHLVLS--SGT--LRISGVALHDQGQYE 518
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
C+A N +G K A L V P ++ P F + P + VE G NV C+ +G P
Sbjct: 519 CQAVNIIGSQKVVAHLTV-------QP--RVTPVFASIPSDTTVEVGANVQLPCSSQGEP 569
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
P +W+KDG +T S + + + L I++V D G Y N +G A S
Sbjct: 570 EPAITWNKDGVQVTESGKFHISPE----GFLTINDVGPADAGRYECVARNTIGSASVSMV 625
Query: 184 LEV 186
L V
Sbjct: 626 LSV 628
Score = 79.0 bits (186), Expect = 1e-14
Identities = 57/179 (31%), Positives = 80/179 (44%), Gaps = 15/179 (8%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSY-DDGTARLKIKQVTAEDEGTYTC 64
G+TV F C+ GNP P+I W + D + DDGT ++ Q T D+G Y C
Sbjct: 277 GNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLDDGTLMIQNTQET--DQGIYQC 334
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
A N G+ K+ + Y SP R PTF P N V GE+VT +C+ G+P
Sbjct: 335 MAKNVAGEVKTQEVTLRY----FGSPAR---PTFVIQPQNTEVLVGESVTLECSATGHPP 387
Query: 125 PWASWDK-DGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASA 182
P SW + D + + R+ + L I V D G Y + N + A+A
Sbjct: 388 PRISWTRGDRTPLPVDPRVNITPSGG----LYIQNVVQGDSGEYACSATNNIDSVHATA 442
Score = 76.6 bits (180), Expect = 6e-14
Identities = 56/184 (30%), Positives = 77/184 (41%), Gaps = 17/184 (9%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G++V EC TG+P P I W + G L I+ V D G Y C
Sbjct: 373 GESVTLECSATGHPPPRISWTRGDRTPLPVDPRVNITPSGG--LYIQNVVQGDSGEYACS 430
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A+N + + A ++V Q P F P ++VV EG+ V F+C KGNP P
Sbjct: 431 ATNNIDSVHATAFIIV-----------QALPQFTVTPQDRVVIEGQTVDFQCEAKGNPPP 479
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
+W K GS ++ R V L I V++ D G Y N +G + A L
Sbjct: 480 VIAWTKGGSQLSVDRRHLVLSS----GTLRISGVALHDQGQYECQAVNIIGSQKVVAHLT 535
Query: 186 VITR 189
V R
Sbjct: 536 VQPR 539
Score = 33.1 bits (72), Expect = 0.78
Identities = 21/86 (24%), Positives = 37/86 (43%), Gaps = 6/86 (6%)
Query: 96 PTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIIT--PSARITVKEKEEIMRI 153
P + P + V G V F C +GNP P W ++ + ++ +R+ + + +M
Sbjct: 263 PRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLDDGTLM-- 320
Query: 154 LEIDEVSIEDVGIYRITVENELGRAE 179
I D GIY+ +N G +
Sbjct: 321 --IQNTQETDQGIYQCMAKNVAGEVK 344
>X90568-1|CAA62188.1|26926|Homo sapiens titin protein.
Length = 26926
Score = 87.4 bits (207), Expect = 3e-17
Identities = 57/184 (30%), Positives = 92/184 (50%), Gaps = 11/184 (5%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCA--DFESSYDDGTARLKIKQVTAEDEGTY 62
+G T FE ++G P P++ WF +VI + S+ DG A+L I VT + G Y
Sbjct: 19 EGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKANSGRY 78
Query: 63 TCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGN 122
+ +A+N G+A S A L+V + ++P P F + V +G V + V G
Sbjct: 79 SLKATNGSGQATSTAELLV---KAETAP-----PNFVQRLQSMTVRQGSQVRLQVRVTGI 130
Query: 123 PSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASA 182
P+P + +DG+ I S + ++ ++ +L I E ED G Y + N +GRA ++A
Sbjct: 131 PNPVVKFYRDGAEIQSSLDFQISQEGDLYSLL-IAEAYPEDSGTYSVNATNSVGRATSTA 189
Query: 183 RLEV 186
L V
Sbjct: 190 ELLV 193
Score = 86.6 bits (205), Expect = 6e-17
Identities = 55/185 (29%), Positives = 81/185 (43%), Gaps = 7/185 (3%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSY----DDGTARLKIKQVTAEDEGT 61
G+ V F +T +P+P + W+ + I+ D + Y D G +L I VT +D+
Sbjct: 25207 GENVRFGVTITVHPEPHVTWYKSGQKIKP-GDNDKKYTFESDKGLYQLTINSVTTDDDAE 25265
Query: 62 YTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKG 121
YT A N G+ A L V T + P F N +EG++V F+ V G
Sbjct: 25266 YTVVARNKYGEDSCKAKLTV--TLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSG 25323
Query: 122 NPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEAS 181
P P W+KDG ++ I + + L I + ED G YR+T N G
Sbjct: 25324 IPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQ 25383
Query: 182 ARLEV 186
A L+V
Sbjct: 25384 AHLQV 25388
Score = 78.6 bits (185), Expect = 2e-14
Identities = 48/166 (28%), Positives = 77/166 (46%), Gaps = 8/166 (4%)
Query: 22 DIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLGKAKSNACLVV 81
D++W + + ++ L IKQ + DEG TC + G K L +
Sbjct: 26570 DVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTL 26629
Query: 82 YHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSAR 141
++ LS AP F + P ++ + EG+NV F C + G PSP W K+ I+ S+
Sbjct: 26630 --SKELSD-----APAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSN 26682
Query: 142 ITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVI 187
+++ + LEI S+ D G Y I +N G+ A+A L V+
Sbjct: 26683 VSISRSRNVYS-LEIRNASVSDSGKYTIKAKNFRGQCSATASLMVL 26727
Score = 77.4 bits (182), Expect = 4e-14
Identities = 54/202 (26%), Positives = 91/202 (45%), Gaps = 20/202 (9%)
Query: 5 DGDTVEFECQVTG-NPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYT 63
+G V++ C++ + + W+ + + +E +Y+DG A L +K +T D+GTY
Sbjct: 25084 EGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYR 25143
Query: 64 CEASNCLGKAKSNACLVV--------YHTRRLSSPGRQMAPTF--------YTYP-FNKV 106
C+ N G+ S A L V Y+ RR ++ T +T P +NK
Sbjct: 25144 CKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNKT 25203
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITP--SARITVKEKEEIMRILEIDEVSIEDV 164
GENV F + +P P +W K G I P + + E ++ + L I+ V+ +D
Sbjct: 25204 AYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDD 25263
Query: 165 GIYRITVENELGRAEASARLEV 186
Y + N+ G A+L V
Sbjct: 25264 AEYTVVARNKYGEDSCKAKLTV 25285
Score = 76.6 bits (180), Expect = 6e-14
Identities = 44/187 (23%), Positives = 83/187 (44%), Gaps = 8/187 (4%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+ + CQ+ G P PDI+W+ + + + ++ S D T L + EDEG YTC
Sbjct: 24050 GEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCI 24109
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A+N +G+ ++++ L++ T + PG + +Y G + G P P
Sbjct: 24110 ATNEVGEVETSSKLLLQATPQF-HPGYPLKEKYYG-------AVGSTLRLHVMYIGRPVP 24161
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
+W ++ S IT++ E ++ + G Y++ + N G +A +E
Sbjct: 24162 AMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVE 24221
Query: 186 VITRSGK 192
+ + K
Sbjct: 24222 IQDKPDK 24228
Score = 74.1 bits (174), Expect = 3e-13
Identities = 52/184 (28%), Positives = 79/184 (42%), Gaps = 6/184 (3%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G F ++G P P I W+ +++ + +D L + + ED YTCE
Sbjct: 3207 GKPARFCAMISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCE 3266
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQM---APTFYTYPFNKVVEEGENVTFKCAVKGN 122
A N G A ++A L V + SP ++M P T + V EG+ F+C V G
Sbjct: 3267 AKNDYGVATTSASLSV-EVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGT 3325
Query: 123 PSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASA 182
SW I PS + + E+ + LEI E ED G Y N +G+ ++A
Sbjct: 3326 DLK-VSWYSKDKKIKPSRFFRMTQFEDTYQ-LEIAEAYPEDEGTYTFVANNAVGQVSSTA 3383
Query: 183 RLEV 186
L +
Sbjct: 3384 NLSL 3387
Score = 73.7 bits (173), Expect = 5e-13
Identities = 51/184 (27%), Positives = 78/184 (42%), Gaps = 8/184 (4%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAE-VIRDCADFESSYDDGTARLKIKQVTAEDEGTYT 63
+G F+ +V G P P+ WFH + ++ D +DGT L I T D G +T
Sbjct: 1424 EGANCRFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWT 1483
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
A N G++ + L V + Q+ P F N ++EG + K GNP
Sbjct: 1484 VVAQNRAGRSSISVILTV------EAVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNP 1537
Query: 124 SPWASWDKDGSIITPSARITVK-EKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASA 182
+P W K+ II P ++ E + L+ID +D Y T N+ GR
Sbjct: 1538 NPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRC 1597
Query: 183 RLEV 186
++ V
Sbjct: 1598 KVNV 1601
Score = 68.5 bits (160), Expect = 2e-11
Identities = 53/196 (27%), Positives = 76/196 (38%), Gaps = 14/196 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
GD V G P P I+WF ++ AD++ +D L I EDEG YTC
Sbjct: 3471 GDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCM 3530
Query: 66 ASNCLGKAKSNACLVVYH--------------TRRLSSPGRQMAPTFYTYPFNKVVEEGE 111
ASN GK +A L + + L G P F +G
Sbjct: 3531 ASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGL 3590
Query: 112 NVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITV 171
F+ V G P+P +W K+ + S T+ +++ ED G+Y
Sbjct: 3591 PAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKA 3650
Query: 172 ENELGRAEASARLEVI 187
EN LG + +A L V+
Sbjct: 3651 ENMLGESTCAAELLVL 3666
Score = 64.9 bits (151), Expect = 2e-10
Identities = 27/77 (35%), Positives = 42/77 (54%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G++V EC ++G P P + W+ I DF+ ++ G ARL I++ AED G +TC
Sbjct: 910 EGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTC 969
Query: 65 EASNCLGKAKSNACLVV 81
A N G ++ L V
Sbjct: 970 SAVNEAGTVSTSCYLAV 986
Score = 62.9 bits (146), Expect = 8e-10
Identities = 37/102 (36%), Positives = 46/102 (45%), Gaps = 1/102 (0%)
Query: 84 TRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARIT 143
T + PG AP F T P + + EG +V F C V GNP P W K G +T R
Sbjct: 1024 TEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYK 1083
Query: 144 VKEKEEIMRI-LEIDEVSIEDVGIYRITVENELGRAEASARL 184
V ++ L I +D G Y I V N+ G ASA L
Sbjct: 1084 VSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1125
Score = 62.9 bits (146), Expect = 8e-10
Identities = 36/96 (37%), Positives = 51/96 (53%), Gaps = 1/96 (1%)
Query: 96 PTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILE 155
PT + +V EGE ++ + P P SW KDG + S R+T+K + I LE
Sbjct: 7890 PTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKN-DHISAHLE 7948
Query: 156 IDEVSIEDVGIYRITVENELGRAEASARLEVITRSG 191
+ + D GIY IT+EN+LG A AS ++VI G
Sbjct: 7949 VPKSVRADAGIYTITLENKLGSATASINVKVIGLPG 7984
Score = 62.1 bits (144), Expect = 1e-09
Identities = 51/192 (26%), Positives = 78/192 (40%), Gaps = 13/192 (6%)
Query: 2 LSCDGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAED-EG 60
+S +GD V +T + + W+ +++ F+ D T L I +V ED +G
Sbjct: 4253 VSEEGDIVHLTTSITNAKE--VNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQG 4310
Query: 61 TYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVK 120
Y CEA N GK ++A L V ++ AP V G F C ++
Sbjct: 4311 EYVCEALNDSGKTATSAKLTVV---------KRAAPVIKRKIEPLEVALGHLAKFTCEIQ 4361
Query: 121 GNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEA 180
P+ W K G I S + +++ + I LEI + D G Y NE G
Sbjct: 4362 SAPNVRFQWFKAGREIYESDKCSIRSSKYISS-LEILRTQVVDCGEYTCKASNEYGSVSC 4420
Query: 181 SARLEVITRSGK 192
+A L V G+
Sbjct: 4421 TATLTVTVPGGE 4432
Score = 58.8 bits (136), Expect = 1e-08
Identities = 43/176 (24%), Positives = 72/176 (40%), Gaps = 8/176 (4%)
Query: 13 CQVTGNPDPDIRWFHYA-EVIRDCADFE-SSYDDGTARLKIKQVTAEDEGTYTCEASNCL 70
C+VTG+P P ++W+ E+I D + + G +L I VT +D Y A+N
Sbjct: 24452 CKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQG 24511
Query: 71 GKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWD 130
G A L V ++ P + + + GE V+ K G P P +W
Sbjct: 24512 GSVSGTASLEVEVPAKIHLP-KTLEGMGAVHALR-----GEVVSIKIPFSGKPDPVITWQ 24565
Query: 131 KDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
K +I + V ++ + V +D G Y + +N G + + L+V
Sbjct: 24566 KGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDV 24621
Score = 58.4 bits (135), Expect = 2e-08
Identities = 30/85 (35%), Positives = 46/85 (54%), Gaps = 1/85 (1%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
V+ G NV V G P P SW KDG+++ P+ I + + + LE+ V+ +D G
Sbjct: 12810 VKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLC-TLELFSVNRKDSGD 12868
Query: 167 YRITVENELGRAEASARLEVITRSG 191
Y IT EN G A+ +L+V+ + G
Sbjct: 12869 YTITAENSSGSKSATIKLKVLDKPG 12893
Score = 56.8 bits (131), Expect = 6e-08
Identities = 31/93 (33%), Positives = 43/93 (46%), Gaps = 1/93 (1%)
Query: 94 MAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRI 153
+A T P + V EGE+ F C G P P +W + G +++ SAR V +
Sbjct: 26062 LAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQV-TTTKYKST 26120
Query: 154 LEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
EI V D G Y + VEN G+ EA L +
Sbjct: 26121 FEISSVQASDEGNYSVVVENSEGKQEAEFTLTI 26153
Score = 54.0 bits (124), Expect = 4e-07
Identities = 44/183 (24%), Positives = 81/183 (44%), Gaps = 21/183 (11%)
Query: 7 DTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEA 66
DT++ C+V+ P ++ W+ E I + +E + L I+ ED G Y C
Sbjct: 5981 DTIKLVCEVS-KPGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQNAHLEDAGNYNCR- 6038
Query: 67 SNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPW 126
L ++++ + V+ ++A F + P N + EGE F C++ P
Sbjct: 6039 ---LPSSRTDGKVKVH----------ELAAEFISKPQNLEILEGEKAEFVCSISKESFP- 6084
Query: 127 ASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W +D + + V + R+L + + +++D+G Y + V G A A+A L V
Sbjct: 6085 VQWKRDDKTLESGDKYDVIADGK-KRVLVVKDATLQDMGTYVVMV----GAARAAAHLTV 6139
Query: 187 ITR 189
I +
Sbjct: 6140 IEK 6142
Score = 53.6 bits (123), Expect = 5e-07
Identities = 31/87 (35%), Positives = 44/87 (50%), Gaps = 1/87 (1%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSY-DDGTARLKIKQVTAEDEGTYT 63
+G V F C+++G P P I W+ + I+ ++ + DG A L+I V EDEG YT
Sbjct: 1258 EGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYT 1317
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSP 90
ASN G A + L V L +P
Sbjct: 1318 AFASNIKGNAICSGKLYVEPAAPLGAP 1344
Score = 53.6 bits (123), Expect = 5e-07
Identities = 31/98 (31%), Positives = 49/98 (50%), Gaps = 2/98 (2%)
Query: 102 PFNKV-VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVS 160
PFN ++ GE++ + V G P P SW KDG + + R+ V E+ +L I E +
Sbjct: 17820 PFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNV-EETATSTVLHIKEGN 17878
Query: 161 IEDVGIYRITVENELGRAEASARLEVITRSGKFYGGLR 198
+D G Y +T N G A + + V+ + G G +R
Sbjct: 17879 KDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGPVR 17916
Score = 53.2 bits (122), Expect = 7e-07
Identities = 46/173 (26%), Positives = 70/173 (40%), Gaps = 16/173 (9%)
Query: 6 GDTVEFECQVTGNPDPDIRWF-HYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
G F +V G PDP+ W+ + ++ R + +D L I+ VTAED +
Sbjct: 2046 GSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMV 2105
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVV--EEGENVTFKCAVKGN 122
+A N G+ S+A L+V + ++ +T VV E+ TF+C
Sbjct: 2106 KAINIAGETSSHAFLLVQAKQLIT----------FTQELQDVVAKEKDTMATFECET-SE 2154
Query: 123 PSPWASWDKDGSII--TPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVEN 173
P W KDG + R+ K + IL ID ED + EN
Sbjct: 2155 PFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVEDEN 2207
Score = 53.2 bits (122), Expect = 7e-07
Identities = 32/99 (32%), Positives = 42/99 (42%), Gaps = 1/99 (1%)
Query: 106 VVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVG 165
VV+ G V F ++G P P A W DGS I TV E + +L I D G
Sbjct: 11024 VVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTV-ETDNFSSVLTIKNCLRRDTG 11082
Query: 166 IYRITVENELGRAEASARLEVITRSGKFYGGLRAYSASP 204
Y+ITV N G + L V+ G G + +P
Sbjct: 11083 EYQITVSNAAGSKTVAVHLTVLDVPGPPTGPINILDVTP 11121
Score = 52.8 bits (121), Expect = 9e-07
Identities = 31/94 (32%), Positives = 44/94 (46%), Gaps = 2/94 (2%)
Query: 96 PTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILE 155
P YP V EGE F+C V G P P +W +G +I S R V + + + L+
Sbjct: 1795 PDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRV--RYDGIHYLD 1852
Query: 156 IDEVSIEDVGIYRITVENELGRAEASARLEVITR 189
I + D G ++T EN G E +LE+ R
Sbjct: 1853 IVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQR 1886
Score = 51.6 bits (118), Expect = 2e-06
Identities = 24/77 (31%), Positives = 38/77 (49%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G V F C+++G P P+I WF I ++ S L+I+ + D G YT
Sbjct: 26650 EGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTI 26709
Query: 65 EASNCLGKAKSNACLVV 81
+A N G+ + A L+V
Sbjct: 26710 KAKNFRGQCSATASLMV 26726
Score = 51.2 bits (117), Expect = 3e-06
Identities = 41/146 (28%), Positives = 59/146 (40%), Gaps = 6/146 (4%)
Query: 46 TARLKIKQVTAEDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNK 105
T I +TA +E + A N G++ V R + P F+T FN
Sbjct: 18853 TLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELP-FHT--FN- 18908
Query: 106 VVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVG 165
V+ E + KG P +W KDG + + R+ V + + L I E S EDVG
Sbjct: 18909 -VKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTS-LSIKEASKEDVG 18966
Query: 166 IYRITVENELGRAEASARLEVITRSG 191
Y + V N G + V+ R G
Sbjct: 18967 TYELCVSNSAGSITVPITIIVLDRPG 18992
Score = 50.4 bits (115), Expect = 5e-06
Identities = 30/93 (32%), Positives = 49/93 (52%), Gaps = 7/93 (7%)
Query: 96 PTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILE 155
P F +Y V+ G+++ + + G P P +W KDG + + RI V + + + L
Sbjct: 16737 PAFSSYS----VQVGQDLKMEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLD-LTTLS 16791
Query: 156 IDEVSIEDVGIYRITVENELGRAEASARLEVIT 188
I E +D G Y ITV N +G+ AS +E++T
Sbjct: 16792 IKETHKDDGGQYGITVANVVGQKTAS--IEIVT 16822
Score = 49.6 bits (113), Expect = 8e-06
Identities = 30/91 (32%), Positives = 43/91 (47%), Gaps = 1/91 (1%)
Query: 96 PTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILE 155
PT + N V EGE+VT +C + G PSP +W ++ I S + + I R++
Sbjct: 897 PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLM- 955
Query: 156 IDEVSIEDVGIYRITVENELGRAEASARLEV 186
I E ED G + + NE G S L V
Sbjct: 956 IREAFAEDSGRFTCSAVNEAGTVSTSCYLAV 986
Score = 49.6 bits (113), Expect = 8e-06
Identities = 27/86 (31%), Positives = 45/86 (52%), Gaps = 3/86 (3%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRI-LEIDEVSIEDVG 165
V G+ + VKG P P +W K+G ++ R+ + +++ R+ L+I E D G
Sbjct: 11423 VRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDL--IQDLPRVELQIKEAVRADHG 11480
Query: 166 IYRITVENELGRAEASARLEVITRSG 191
Y I+ +N G A+ SA + V+ R G
Sbjct: 11481 KYIISAKNSSGHAQGSAIVNVLDRPG 11506
Score = 49.2 bits (112), Expect = 1e-05
Identities = 35/157 (22%), Positives = 69/157 (43%), Gaps = 7/157 (4%)
Query: 36 ADFESSYDDGTARLKIKQVTAEDEGTYT---CEASNCLGKAKSNACLVVYHTRRLSSPG- 91
+ F SS +K ++A+ + E S+ SN + T ++ G
Sbjct: 26768 SSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMTQLESSTSKMLKAGI 26827
Query: 92 RQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSII--TPSARITVKEKEE 149
R + P P + ++EG+ +T CA G P+P +W G I R ++ ++
Sbjct: 26828 RGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDD 26887
Query: 150 IMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
+ ++ +D V +D G+Y +++ NE G A+ + +
Sbjct: 26888 LTTLIIMD-VQKQDGGLYTLSLGNEFGSDSATVNIHI 26923
Score = 48.4 bits (110), Expect = 2e-05
Identities = 24/86 (27%), Positives = 41/86 (47%), Gaps = 1/86 (1%)
Query: 106 VVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVG 165
+ +E N K +KG P+P SW K + R++V E + L + + D G
Sbjct: 13496 LAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSV-ESSAVNTTLIVYDCQKSDAG 13554
Query: 166 IYRITVENELGRAEASARLEVITRSG 191
Y IT++N G E + ++V+ + G
Sbjct: 13555 KYTITLKNVAGTKEGTISIKVVGKPG 13580
Score = 48.4 bits (110), Expect = 2e-05
Identities = 27/103 (26%), Positives = 46/103 (44%), Gaps = 1/103 (0%)
Query: 106 VVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVG 165
+++ GE + V G P P W KDG + +A++ +K + ++ D D G
Sbjct: 14975 ILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTR-RDSG 15033
Query: 166 IYRITVENELGRAEASARLEVITRSGKFYGGLRAYSASPRKCL 208
Y +T N G A+ ++V+ R G G L + KC+
Sbjct: 15034 AYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCV 15076
Score = 48.0 bits (109), Expect = 3e-05
Identities = 25/96 (26%), Positives = 42/96 (43%), Gaps = 4/96 (4%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G++ F C G P P + W +V+ A + + + +I V A DEG Y+
Sbjct: 26077 EGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSV 26136
Query: 65 EASNCLGKAKSNACLVVYHTR----RLSSPGRQMAP 96
N GK ++ L + R ++SP R +P
Sbjct: 26137 VVENSEGKQEAEFTLTIQKARVTEKAVTSPPRVKSP 26172
Score = 47.6 bits (108), Expect = 3e-05
Identities = 30/83 (36%), Positives = 37/83 (44%)
Query: 104 NKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIED 163
N + EG VTF C + G P P +W KDG I R + ++ L I V ED
Sbjct: 1253 NYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPED 1312
Query: 164 VGIYRITVENELGRAEASARLEV 186
GIY N G A S +L V
Sbjct: 1313 EGIYTAFASNIKGNAICSGKLYV 1335
Score = 47.6 bits (108), Expect = 3e-05
Identities = 44/191 (23%), Positives = 78/191 (40%), Gaps = 18/191 (9%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G+T F C+++ + + WF + S + T +L++K+VT +D
Sbjct: 5090 EGETATFVCELS-HEKMHVVWFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLDDISQIKA 5148
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
+ + S A L V + P F +K E + +T KC V +
Sbjct: 5149 QVK----ELSSTAQLKVL----------EADPYFTVKLHDKTAVEKDEITLKCEVSKDVP 5194
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
W KDG I PS + ++K + + RIL+I + ++D G Y + +A +
Sbjct: 5195 --VKWFKDGEEIVPSPKYSIK-ADGLRRILKIKKADLKDKGEYVCDCGTDKTKANVTVEA 5251
Query: 185 EVITRSGKFYG 195
+I YG
Sbjct: 5252 RLIEVEKPLYG 5262
Score = 47.6 bits (108), Expect = 3e-05
Identities = 35/98 (35%), Positives = 41/98 (41%), Gaps = 9/98 (9%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADF------ESSYDDGTARLKIKQVTAEDE 59
G+ V VTG P P I W VI D E S + L I + ED+
Sbjct: 8916 GEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDK 8975
Query: 60 GTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPT 97
GTYT ASN LG N + VY SP R +A T
Sbjct: 8976 GTYTVTASNRLGSVFRNVHVEVYDR---PSPPRNLAVT 9010
Score = 47.6 bits (108), Expect = 3e-05
Identities = 31/108 (28%), Positives = 48/108 (44%), Gaps = 2/108 (1%)
Query: 106 VVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVG 165
VV+ GE + + G P P SW KDG I AR + + +L + + D G
Sbjct: 19303 VVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDN-HTLLTVKDCIRRDTG 19361
Query: 166 IYRITVENELGRAEASARLEVITRSGKFYGGLRAYSASPRKC-LSYRR 212
Y +T++N G + +V+ + G G L + KC LS+ R
Sbjct: 19362 QYVLTLKNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLSWGR 19409
Score = 47.6 bits (108), Expect = 3e-05
Identities = 24/76 (31%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
Query: 106 VVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVG 165
+ + GE+V KG P P +W KD + AR ++ E + +L I +V+ D G
Sbjct: 20785 IAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSI-ENTDSSSLLTIPQVTRNDTG 20843
Query: 166 IYRITVENELGRAEAS 181
Y +T+EN +G ++S
Sbjct: 20844 KYILTIENGVGEPKSS 20859
Score = 47.2 bits (107), Expect = 4e-05
Identities = 27/73 (36%), Positives = 36/73 (49%), Gaps = 3/73 (4%)
Query: 116 KCAVK--GNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVEN 173
K AVK G P P A W KDG IT + + E + LEI + D G+Y TV+N
Sbjct: 26373 KFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGF-FLEIHKTDTSDSGLYTCTVKN 26431
Query: 174 ELGRAEASARLEV 186
G +S +L +
Sbjct: 26432 SAGSVSSSCKLTI 26444
Score = 46.8 bits (106), Expect = 6e-05
Identities = 34/94 (36%), Positives = 46/94 (48%), Gaps = 3/94 (3%)
Query: 95 APTFYTYPFNKVVE-EGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRI 153
APTF T P VV EG TF+ + G P P SW +DG +I+ S V+ R
Sbjct: 5 APTF-TQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRA 63
Query: 154 -LEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
L I V+ + G Y + N G+A ++A L V
Sbjct: 64 KLTIPAVTKANSGRYSLKATNGSGQATSTAELLV 97
Score = 46.8 bits (106), Expect = 6e-05
Identities = 27/85 (31%), Positives = 41/85 (48%), Gaps = 3/85 (3%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
++ G+ + +KG P P +W K+ ARI V + LEI + ED GI
Sbjct: 10733 IKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTP---VGSKLEIRNAAHEDGGI 10789
Query: 167 YRITVENELGRAEASARLEVITRSG 191
Y +TVEN G S ++ V+ + G
Sbjct: 10790 YSLTVENPAGSKTVSVKVLVLDKPG 10814
Score = 46.4 bits (105), Expect = 8e-05
Identities = 26/92 (28%), Positives = 45/92 (48%), Gaps = 1/92 (1%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
V G V + G P P ASW GS + S R+TV+ ++ + L I E +I D G
Sbjct: 23253 VPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAK-LTIRETTIRDTGE 23311
Query: 167 YRITVENELGRAEASARLEVITRSGKFYGGLR 198
Y + ++N G + ++ ++ + G G ++
Sbjct: 23312 YTLELKNVTGTTSETIKVIILDKPGPPTGPIK 23343
Score = 46.0 bits (104), Expect = 1e-04
Identities = 36/165 (21%), Positives = 67/165 (40%), Gaps = 2/165 (1%)
Query: 51 IKQVTAEDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEG 110
I +T + + A N +G SN VV + S G + Y G
Sbjct: 20332 ISGLTQNSQYEFRVFARNAVGSI-SNPSEVVGPITCIDSYGGPVIDLPLEYTEVVKYRAG 20390
Query: 111 ENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRIT 170
+V + + G P+P W KD + +A + V+ ++ IL I + + G Y +
Sbjct: 20391 TSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASIL-IKDADRLNSGCYELK 20449
Query: 171 VENELGRAEASARLEVITRSGKFYGGLRAYSASPRKCLSYRRRPS 215
+ N + A A+ R++++ + G G + + + K R P+
Sbjct: 20450 LRNAMASASATIRVQILDKPGPPGGPIEFKTVTAEKITLLWRPPA 20494
Score = 46.0 bits (104), Expect = 1e-04
Identities = 27/95 (28%), Positives = 43/95 (45%), Gaps = 5/95 (5%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+++ + V G P P + WF I + E + G+ L ++ T + G YT E
Sbjct: 21476 GESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITNVLGSTSLFVRDATRDHRGVYTVE 21535
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYT 100
A N G AK+ + V T PG+ + P +T
Sbjct: 21536 AKNASGSAKAEIKVKVQDT-----PGKVVGPIRFT 21565
Score = 45.2 bits (102), Expect = 2e-04
Identities = 49/189 (25%), Positives = 75/189 (39%), Gaps = 21/189 (11%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G T EC+V+ + ++WF I +E D +L I T ED TYTC
Sbjct: 5801 EGATAVLECEVS-RENAKVKWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTC 5859
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
+A + K N +V H L R + + V E E F+C + +
Sbjct: 5860 DAKDF--KTSCNLNVVPPHVEFL----RPLT--------DLQVREKEMARFECEL-SREN 5904
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
W KDG+ I + + K + RIL I++ ++D Y E+ A S L
Sbjct: 5905 AKVKWFKDGAEIKKGKKYDIISKGAV-RILVINKCLLDDEAEYSC----EVRTARTSGML 5959
Query: 185 EVITRSGKF 193
V+ F
Sbjct: 5960 TVLEEEAVF 5968
Score = 45.2 bits (102), Expect = 2e-04
Identities = 27/98 (27%), Positives = 46/98 (46%), Gaps = 11/98 (11%)
Query: 106 VVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDV- 164
+++ GE++ K V+G P P +W KDG I + EI +L + + D
Sbjct: 21472 IIKSGESLRIKALVQGRPVPRVTWFKDG------VEIEKRMNMEITNVLGSTSLFVRDAT 21525
Query: 165 ----GIYRITVENELGRAEASARLEVITRSGKFYGGLR 198
G+Y + +N G A+A +++V GK G +R
Sbjct: 21526 RDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIR 21563
Score = 44.8 bits (101), Expect = 2e-04
Identities = 25/78 (32%), Positives = 38/78 (48%), Gaps = 2/78 (2%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYD--DGTARLKIKQVTAEDEGTY 62
+G +V F CQV GNP P + W + ++ SY+ G +L I A+D G Y
Sbjct: 1049 EGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEY 1108
Query: 63 TCEASNCLGKAKSNACLV 80
T N G+ ++A L+
Sbjct: 1109 TIVVRNKHGETSASASLL 1126
Score = 44.8 bits (101), Expect = 2e-04
Identities = 31/112 (27%), Positives = 46/112 (41%), Gaps = 4/112 (3%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G+T F C+VTG P P + W+ ++IR F Y DG L I + D G
Sbjct: 1808 EGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRY-DGIHYLDIVDCKSYDTGEVKV 1866
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGR---QMAPTFYTYPFNKVVEEGENV 113
A N G + L + S R + P F+ + K+ E + V
Sbjct: 1867 TAENPEGVIEHKVKLEIQQREDFRSVLRRAPEPRPEFHVHEPGKLQFEVQKV 1918
Score = 44.8 bits (101), Expect = 2e-04
Identities = 51/183 (27%), Positives = 70/183 (38%), Gaps = 15/183 (8%)
Query: 6 GDTVEFECQVTGNPDPDIR-WFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
G + FEC V+ P I W IR+ D +L I V D G YTC
Sbjct: 4636 GSSAIFECLVS--PSTAITTWMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSDAGEYTC 4693
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
+ S A LVV P R + T V +G+ + C + N
Sbjct: 4694 VLRLGNKEKTSTAKLVVEEL-----PVRFVK----TLEEEVTVVKGQPLYLSCEL--NKE 4742
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
W KDG I+ V +MR L I++ D G Y +TVEN E S+ +
Sbjct: 4743 RDVVWRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGTYTVTVEN-ANNLECSSCV 4801
Query: 185 EVI 187
+V+
Sbjct: 4802 KVV 4804
Score = 44.8 bits (101), Expect = 2e-04
Identities = 46/163 (28%), Positives = 67/163 (41%), Gaps = 19/163 (11%)
Query: 53 QVTAED-----EGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVV 107
Q T ED E + +A N G +K +A + +R P P+ F +V
Sbjct: 9578 QFTVEDLVEGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMP-----PSIDLKEFMEV- 9631
Query: 108 EEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSI------ 161
EEG NV +KG P P +W K P + V + +++ D ++
Sbjct: 9632 EEGTNVNIVAKIKGVPFPTLTWFK-APPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSR 9690
Query: 162 -EDVGIYRITVENELGRAEASARLEVITRSGKFYGGLRAYSAS 203
D G+Y IT N LG A RL V+ R G G ++ S S
Sbjct: 9691 RSDTGLYTITAVNNLGTASKEMRLNVLGRPGPPVGPIKFESVS 9733
Score = 44.8 bits (101), Expect = 2e-04
Identities = 26/99 (26%), Positives = 43/99 (43%), Gaps = 1/99 (1%)
Query: 93 QMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMR 152
Q+ P P ++ G+ + + V G P P W K + S+ + V K +
Sbjct: 12399 QLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAV-HKADSSS 12457
Query: 153 ILEIDEVSIEDVGIYRITVENELGRAEASARLEVITRSG 191
IL I +V+ +D G Y +T EN G ++ V+ G
Sbjct: 12458 ILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPG 12496
Score = 44.4 bits (100), Expect = 3e-04
Identities = 28/93 (30%), Positives = 41/93 (44%), Gaps = 1/93 (1%)
Query: 95 APTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDG-SIITPSARITVKEKEEIMRI 153
AP F N V N T C V G+P P W + G II + ++E +
Sbjct: 24430 APHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQ 24489
Query: 154 LEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
L I V+ +D +Y++ N+ G +A LEV
Sbjct: 24490 LIIASVTDDDATVYQVRATNQGGSVSGTASLEV 24522
Score = 44.0 bits (99), Expect = 4e-04
Identities = 36/145 (24%), Positives = 59/145 (40%), Gaps = 7/145 (4%)
Query: 48 RLKIKQVTAEDEGTYTCEASNCLGKAKS-NACLVVYHTRRLSSPGRQMAPTFYTYPFNKV 106
R + + A +E + A N GK S + RL++P + F V
Sbjct: 21815 RYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQ---THV 21871
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
V G ++ A +G P+P A W K S ++ A I + L ++ + D G
Sbjct: 21872 VRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRADIHTTDS---FSTLTVENCNRNDAGK 21928
Query: 167 YRITVENELGRAEASARLEVITRSG 191
Y +TVEN G + ++V+ G
Sbjct: 21929 YTLTVENNSGSKSITFTVKVLDTPG 21953
Score = 43.6 bits (98), Expect = 6e-04
Identities = 30/103 (29%), Positives = 46/103 (44%), Gaps = 6/103 (5%)
Query: 92 RQMAPTFYTYPFNK---VVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKE 148
R+MAP F + VV G ++ +KG P+P +W KD + A I E
Sbjct: 14273 REMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANI---ENT 14329
Query: 149 EIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVITRSG 191
E +L I E + D G + +T+EN G+ + V+ G
Sbjct: 14330 ESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPG 14372
Score = 43.6 bits (98), Expect = 6e-04
Identities = 24/69 (34%), Positives = 34/69 (49%), Gaps = 3/69 (4%)
Query: 119 VKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRA 178
+KG P P W+K I+T A+I V +L ID V+ D G Y +T+EN G
Sbjct: 18634 IKGRPEPEVKWEKAEGILTDRAQIEVTSS---FTMLVIDNVTRFDSGRYNLTLENNSGSK 18690
Query: 179 EASARLEVI 187
A + V+
Sbjct: 18691 TAFVNVRVL 18699
Score = 43.2 bits (97), Expect = 7e-04
Identities = 24/85 (28%), Positives = 36/85 (42%), Gaps = 1/85 (1%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
V+ G + V G P P +W K I+ RIT++ + + +D D G
Sbjct: 7205 VKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDS-KRSDTGT 7263
Query: 167 YRITVENELGRAEASARLEVITRSG 191
Y I N GRA A + V+ + G
Sbjct: 7264 YIIEAVNVCGRATAVVEVNVLDKPG 7288
Score = 43.2 bits (97), Expect = 7e-04
Identities = 29/88 (32%), Positives = 41/88 (46%), Gaps = 5/88 (5%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSII---TPSARITVKE--KEEIMRILEIDEVSI 161
V+ GE V V G P P W K+ ++I T + +IT +E + E L I +
Sbjct: 8913 VKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVR 8972
Query: 162 EDVGIYRITVENELGRAEASARLEVITR 189
ED G Y +T N LG + +EV R
Sbjct: 8973 EDKGTYTVTASNRLGSVFRNVHVEVYDR 9000
Score = 43.2 bits (97), Expect = 7e-04
Identities = 26/103 (25%), Positives = 47/103 (45%), Gaps = 4/103 (3%)
Query: 107 VEEGENVTFKCAVKGNPSPWASW--DKDGSIITPSARITVKEKEEIMRILEIDEVSIEDV 164
V+ G+ + + V+G P P +W DKD + +T S R+ + + + + + + D
Sbjct: 11716 VKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSK-FSLTKAKRSDG 11774
Query: 165 GIYRITVENELGRAEASARLEVITRSGKFYGGLRAYSASPRKC 207
G Y +T N G A A + V+ + G L+ S +C
Sbjct: 11775 GKYVVTATNTAGSFVAYATVNVLDKPGP-VRNLKIVDVSSDRC 11816
Score = 43.2 bits (97), Expect = 7e-04
Identities = 26/91 (28%), Positives = 39/91 (42%), Gaps = 5/91 (5%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+ ++ E V G P P+I W E ++ + L IK+ +D G YT
Sbjct: 17829 GEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVT 17888
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAP 96
A+N G A N ++V L PG + P
Sbjct: 17889 ATNSAGTATENLSVIV-----LEKPGPPVGP 17914
Score = 42.7 bits (96), Expect = 0.001
Identities = 33/142 (23%), Positives = 57/142 (40%), Gaps = 7/142 (4%)
Query: 51 IKQVTAEDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKV-VEE 109
+K + D Y A N +G+ K + C T+ ++ PT + +K+ +
Sbjct: 10281 VKGLKEGDTYEYRVSAVNIVGQGKPSFC-----TKPITCKDELAPPTLHLDFRDKLTIRV 10335
Query: 110 GENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRI 169
GE G P P SW KD + + R +K + + +I + D G Y +
Sbjct: 10336 GEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKI-KAKRSDSGKYCV 10394
Query: 170 TVENELGRAEASARLEVITRSG 191
VEN G + ++ V+ G
Sbjct: 10395 VVENSTGSRKGFCQVNVVDHPG 10416
Score = 42.7 bits (96), Expect = 0.001
Identities = 27/95 (28%), Positives = 38/95 (40%), Gaps = 5/95 (5%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+ E V+G P P + W + + A E D + L K T D G YT
Sbjct: 14979 GEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLT 15038
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYT 100
A+N G AK +++ + L PG P T
Sbjct: 15039 ATNPGGFAKH-----IFNVKVLDRPGPPEGPLAVT 15068
Score = 42.7 bits (96), Expect = 0.001
Identities = 19/56 (33%), Positives = 31/56 (55%), Gaps = 1/56 (1%)
Query: 22 DIRWFHYAEVIRDCADFESSYD-DGTARLKIKQVTAEDEGTYTCEASNCLGKAKSN 76
++ W+ + +++ F+ Y DGT LKI +T D+G Y CE S G +K+N
Sbjct: 26251 EVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTN 26306
Score = 42.3 bits (95), Expect = 0.001
Identities = 23/76 (30%), Positives = 34/76 (44%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G T+ +V G P+PDI W +V+ + D L+IK+ D G Y
Sbjct: 11426 GQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKYIIS 11485
Query: 66 ASNCLGKAKSNACLVV 81
A N G A+ +A + V
Sbjct: 11486 AKNSSGHAQGSAIVNV 11501
Score = 42.3 bits (95), Expect = 0.001
Identities = 24/85 (28%), Positives = 39/85 (45%), Gaps = 3/85 (3%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
+ G ++ +V G P P +W K G + A I E + L +D+V+ D G
Sbjct: 22961 IRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSL---LIVDKVNRYDAGK 23017
Query: 167 YRITVENELGRAEASARLEVITRSG 191
Y I EN+ G+ A+ ++V G
Sbjct: 23018 YTIEAENQSGKKSATVLVKVYDTPG 23042
Score = 42.3 bits (95), Expect = 0.001
Identities = 24/81 (29%), Positives = 36/81 (44%), Gaps = 3/81 (3%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
V +G + +KG P P W K+G I+ A I E + I E D D G
Sbjct: 23651 VRQGGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETHTELVIKEADR---GDSGT 23707
Query: 167 YRITVENELGRAEASARLEVI 187
Y + +EN+ G+ ++ VI
Sbjct: 23708 YDLVLENKCGKKAVYIKVRVI 23728
Score = 42.3 bits (95), Expect = 0.001
Identities = 21/72 (29%), Positives = 30/72 (41%)
Query: 10 EFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNC 69
+F + TG P P W + I ++ S D G L+I + D G YTC N
Sbjct: 26373 KFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNS 26432
Query: 70 LGKAKSNACLVV 81
G S+ L +
Sbjct: 26433 AGSVSSSCKLTI 26444
Score = 41.9 bits (94), Expect = 0.002
Identities = 30/126 (23%), Positives = 50/126 (39%), Gaps = 4/126 (3%)
Query: 51 IKQVTAEDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEG 110
++ +T +E T+ A N G++ V + P + + K G
Sbjct: 14527 VRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVIAKA---G 14583
Query: 111 ENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRIT 170
+N+ + V G P P +W K I+ + R+ E IL I+E D G Y +T
Sbjct: 14584 DNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNF-ETTATSTILNINECVRSDSGPYPLT 14642
Query: 171 VENELG 176
N +G
Sbjct: 14643 ARNIVG 14648
Score = 41.5 bits (93), Expect = 0.002
Identities = 29/95 (30%), Positives = 37/95 (38%)
Query: 92 RQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIM 151
R P F P + EG N F V G P P W DG I V KE+
Sbjct: 1407 RLYKPVFVLKPVSFKCLEGANCRFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGT 1466
Query: 152 RILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
+ L I + D G + + +N GR+ S L V
Sbjct: 1467 QSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTV 1501
Score = 41.5 bits (93), Expect = 0.002
Identities = 38/138 (27%), Positives = 59/138 (42%), Gaps = 10/138 (7%)
Query: 54 VTAEDEGTYTCEASNCLGKAKSNACLV----VYHTRRLSSPGRQMAPTFYTYPFNKVVEE 109
++AE+EG ++ E L K L+ VY T+ S P F N +
Sbjct: 3414 LSAEEEGLHSAELQ--LSKINETLELLSESPVYPTK-FDSEKEGTGPIFIKEVSNADISM 3470
Query: 110 GENVTFKCAVKGNPSPWASWDKDGSIITPSARIT-VKEKEEIMRILEIDEVSIEDVGIYR 168
G+ T V G P P W +G ++TPSA V + ++ I+ +ED G Y
Sbjct: 3471 GDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILF--TKLEDEGEYT 3528
Query: 169 ITVENELGRAEASARLEV 186
N+ G+ SA L++
Sbjct: 3529 CMASNDYGKTICSAYLKI 3546
Score = 41.5 bits (93), Expect = 0.002
Identities = 27/97 (27%), Positives = 43/97 (44%), Gaps = 2/97 (2%)
Query: 96 PTFYTYPFNK-VVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRIL 154
P + FN V GE++ G P+P +W KD + + R+ E E +L
Sbjct: 15650 PPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNA-ESTENNSLL 15708
Query: 155 EIDEVSIEDVGIYRITVENELGRAEASARLEVITRSG 191
I + EDVG Y + + N G A + + V+ + G
Sbjct: 15709 TIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPG 15745
Score = 41.5 bits (93), Expect = 0.002
Identities = 27/103 (26%), Positives = 44/103 (42%), Gaps = 2/103 (1%)
Query: 106 VVEEGENVTFKCAVKGNPSPWASWDKDG-SIITPSARITVKEKEEIMRILEIDEVSIEDV 164
VV GE + ++G P P W KDG + +AR+ +K + L + + D
Sbjct: 18221 VVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQ-KTTLVVKDCIRTDG 18279
Query: 165 GIYRITVENELGRAEASARLEVITRSGKFYGGLRAYSASPRKC 207
G Y + + N G ++V+ R G G L+ + KC
Sbjct: 18280 GQYILKLSNVGGTKSIPITVKVLDRPGSPEGPLKVTGVTAEKC 18322
Score = 41.1 bits (92), Expect = 0.003
Identities = 25/102 (24%), Positives = 43/102 (42%), Gaps = 1/102 (0%)
Query: 106 VVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVG 165
VV GE+ + G P P W K ++ +AR+ +K + + D V + D G
Sbjct: 16057 VVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRV-DSG 16115
Query: 166 IYRITVENELGRAEASARLEVITRSGKFYGGLRAYSASPRKC 207
Y + +N G + ++V+ R G G + + KC
Sbjct: 16116 NYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISGVTAEKC 16157
Score = 41.1 bits (92), Expect = 0.003
Identities = 27/102 (26%), Positives = 41/102 (40%), Gaps = 1/102 (0%)
Query: 106 VVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVG 165
VV GE + V G P P W + I SAR +K + ++ D + I D G
Sbjct: 17139 VVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRI-DGG 17197
Query: 166 IYRITVENELGRAEASARLEVITRSGKFYGGLRAYSASPRKC 207
Y + N G ++V+ R G G ++ + KC
Sbjct: 17198 QYILRASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKC 17239
Score = 41.1 bits (92), Expect = 0.003
Identities = 24/91 (26%), Positives = 33/91 (36%), Gaps = 5/91 (5%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G VE + G P P WF +R+ A+L I++ T D G YT E
Sbjct: 23256 GRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLE 23315
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAP 96
N G +++ L PG P
Sbjct: 23316 LKNVTGTTSETIKVII-----LDKPGPPTGP 23341
Score = 40.3 bits (90), Expect = 0.005
Identities = 19/76 (25%), Positives = 32/76 (42%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G F V P +++W+H +++ + + G L+I +D GTY
Sbjct: 25891 GQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAV 25950
Query: 66 ASNCLGKAKSNACLVV 81
+N G+A A L V
Sbjct: 25951 CTNYKGEASDYATLDV 25966
Score = 39.9 bits (89), Expect = 0.007
Identities = 43/177 (24%), Positives = 83/177 (46%), Gaps = 22/177 (12%)
Query: 11 FECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCL 70
FEC +T + ++ W ++I+ F+ D L I +DEG YT E
Sbjct: 5008 FECVLTR--EANVIWSKGPDIIKSSDKFDIIADGKKHILVINDSQFDDEGVYTAEVE--- 5062
Query: 71 GKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWD 130
GK K++A L V R + M+P ++ V+EGE TF C + + W
Sbjct: 5063 GK-KTSARLFVTGIRL-----KFMSPL-----EDQTVKEGETATFVCEL-SHEKMHVVWF 5110
Query: 131 KDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVI 187
K+ + + S + + + + + LE+ EV+++D+ ++ ++ ++A+L+V+
Sbjct: 5111 KNDAKLHTSRTVLISSEGKTHK-LEMKEVTLDDIS----QIKAQVKELSSTAQLKVL 5162
Score = 39.9 bits (89), Expect = 0.007
Identities = 24/99 (24%), Positives = 42/99 (42%), Gaps = 1/99 (1%)
Query: 110 GENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRI 169
G T + G P+P +W + + + R+++ ++ L + + D G Y +
Sbjct: 22165 GSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKD-RTTLTVKDSMRGDSGRYFL 22223
Query: 170 TVENELGRAEASARLEVITRSGKFYGGLRAYSASPRKCL 208
T+EN G S + VI R G G + S S C+
Sbjct: 22224 TLENTAGVKTFSVTVVVIGRPGPVTGPIEVSSVSAESCV 22262
Score = 39.5 bits (88), Expect = 0.009
Identities = 23/66 (34%), Positives = 27/66 (40%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+T E V G P P I W + I + A E D A L +K D G Y
Sbjct: 17143 GETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILR 17202
Query: 66 ASNCLG 71
ASN G
Sbjct: 17203 ASNVAG 17208
Score = 38.3 bits (85), Expect = 0.021
Identities = 29/97 (29%), Positives = 44/97 (45%), Gaps = 4/97 (4%)
Query: 95 APTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRIL 154
AP T + VV+ G+ +T P A W K+ ++ T E+ RIL
Sbjct: 6502 APKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKTIDTTAEQTSF-RIL 6560
Query: 155 EIDEVSIEDVGIYRITVENELGRAEASARLEVITRSG 191
E + D G Y+I ++N+ G+AE L+VI G
Sbjct: 6561 EAKK---GDKGRYKIVLQNKHGKAEGFINLKVIDVPG 6594
Score = 38.3 bits (85), Expect = 0.021
Identities = 24/93 (25%), Positives = 40/93 (43%), Gaps = 7/93 (7%)
Query: 106 VVEEGENVTFKCAVKGNPSPWASWDKDGSI-------ITPSARITVKEKEEIMRILEIDE 158
V + G + +KG P+P +SW+ DG + E E ++ I E
Sbjct: 9324 VCKAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPE 9383
Query: 159 VSIEDVGIYRITVENELGRAEASARLEVITRSG 191
G Y IT +N+ G+ A+ R++V+ G
Sbjct: 9384 CKRSHTGKYSITAKNKAGQKTANCRVKVMDVPG 9416
Score = 38.3 bits (85), Expect = 0.021
Identities = 29/101 (28%), Positives = 42/101 (41%), Gaps = 5/101 (4%)
Query: 95 APTFYTYPFNK---VVEEGENVTFKC-AVKGNPSPWASWDKDGSIITPSARITVKEKEEI 150
APT P K ++ G+ + ++ G P P +SW K G I PS IT
Sbjct: 13878 APTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPS-DITQITSTPT 13936
Query: 151 MRILEIDEVSIEDVGIYRITVENELGRAEASARLEVITRSG 191
+L I + +D G Y IT N G ++ V+ G
Sbjct: 13937 SSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDVPG 13977
Score = 38.3 bits (85), Expect = 0.021
Identities = 22/91 (24%), Positives = 36/91 (39%), Gaps = 5/91 (5%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G++ + + + G P P I+W + + + A E D L +K D G Y +
Sbjct: 16061 GESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILK 16120
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAP 96
A N G+ V + + L PG P
Sbjct: 16121 AKNVAGERS-----VTVNVKVLDRPGPPEGP 16146
Score = 38.3 bits (85), Expect = 0.021
Identities = 25/92 (27%), Positives = 39/92 (42%), Gaps = 2/92 (2%)
Query: 101 YPFNKV-VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEV 159
+P + V V G N+ + G P P + +DG + + R + E + I + E
Sbjct: 19984 FPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTI-NLKES 20042
Query: 160 SIEDVGIYRITVENELGRAEASARLEVITRSG 191
D G Y IT N G +A + V+ R G
Sbjct: 20043 VTADAGRYEITAANSSGTTKAFINIVVLDRPG 20074
Score = 37.9 bits (84), Expect = 0.027
Identities = 29/98 (29%), Positives = 43/98 (43%), Gaps = 1/98 (1%)
Query: 89 SPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKE 148
SP + AP + ++ V +G + F+ V G P P W K+G I S RI E
Sbjct: 2026 SPSME-APKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPE 2084
Query: 149 EIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
+ + L I +V+ ED + N G + A L V
Sbjct: 2085 DNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLV 2122
Score = 37.9 bits (84), Expect = 0.027
Identities = 22/80 (27%), Positives = 35/80 (43%), Gaps = 1/80 (1%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
V+ G+ F + G P P SW K+ +++ + + +L I E ED +
Sbjct: 3204 VQSGKPARFCAMISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLI-EAFPEDAAV 3262
Query: 167 YRITVENELGRAEASARLEV 186
Y +N+ G A SA L V
Sbjct: 3263 YTCEAKNDYGVATTSASLSV 3282
Score = 37.5 bits (83), Expect = 0.036
Identities = 21/86 (24%), Positives = 38/86 (44%), Gaps = 1/86 (1%)
Query: 106 VVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVG 165
++ G + VKG P P +W K + + +K + L + V+ D G
Sbjct: 13207 ILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTD-FDTFLRCENVNKYDAG 13265
Query: 166 IYRITVENELGRAEASARLEVITRSG 191
Y +T+EN G+ E + ++V+ G
Sbjct: 13266 KYILTLENSCGKKEYTIVVKVLDTPG 13291
Score = 37.1 bits (82), Expect = 0.048
Identities = 21/75 (28%), Positives = 32/75 (42%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+ V+ G P P + W + + A + D ++ L I QVT D G Y
Sbjct: 20789 GEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILT 20848
Query: 66 ASNCLGKAKSNACLV 80
N +G+ KS+ V
Sbjct: 20849 IENGVGEPKSSTVSV 20863
Score = 36.7 bits (81), Expect = 0.063
Identities = 40/162 (24%), Positives = 69/162 (42%), Gaps = 17/162 (10%)
Query: 10 EFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNC 69
E EC V+ + + +W+H ++ + + G L +K VT ED+G Y+
Sbjct: 2239 ELECIVSPE-NIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVID-- 2295
Query: 70 LGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASW 129
K C +L R +A ++ V EG+ V + V S W
Sbjct: 2296 ---GKKTTC-------KLKMKPRPIA--ILQGLSDQKVCEGDIVQLEVKV-SLESVEGVW 2342
Query: 130 DKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITV 171
KDG + PS R+ + ++ +L I++++ ED G Y T+
Sbjct: 2343 MKDGQEVQPSDRVHIVIDKQ-SHMLLIEDMTKEDAGNYSFTI 2383
Score = 36.7 bits (81), Expect = 0.063
Identities = 26/96 (27%), Positives = 38/96 (39%), Gaps = 1/96 (1%)
Query: 110 GENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRI 169
G+N F V+ P+ W +G + S++I ++ LEI + +D G YR
Sbjct: 25891 GQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLT-LEILDCHTDDSGTYRA 25949
Query: 170 TVENELGRAEASARLEVITRSGKFYGGLRAYSASPR 205
N G A A L+V Y R PR
Sbjct: 25950 VCTNYKGEASDYATLDVTGGDYTTYASQRRDEEVPR 25985
Score = 36.3 bits (80), Expect = 0.084
Identities = 23/81 (28%), Positives = 35/81 (43%), Gaps = 3/81 (3%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
+ G ++ +KG P+P W K I +A I V L +D V+ D G
Sbjct: 16457 IRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSS---FTSLVLDNVNRYDSGK 16513
Query: 167 YRITVENELGRAEASARLEVI 187
Y +T+EN G A + V+
Sbjct: 16514 YTLTLENSSGTKSAFVTVRVL 16534
Score = 36.3 bits (80), Expect = 0.084
Identities = 24/86 (27%), Positives = 34/86 (39%), Gaps = 3/86 (3%)
Query: 106 VVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVG 165
VV G + KG P P +W ++ T +I EK L ID D G
Sbjct: 17538 VVRAGGSARIHIPFKGRPMPEITWSREEGEFTDKVQI---EKGVNYTQLSIDNCDRNDAG 17594
Query: 166 IYRITVENELGRAEASARLEVITRSG 191
Y + +EN G A ++V+ G
Sbjct: 17595 KYILKLENSSGSKSAFVTVKVLDTPG 17620
Score = 35.9 bits (79), Expect = 0.11
Identities = 45/178 (25%), Positives = 69/178 (38%), Gaps = 22/178 (12%)
Query: 11 FECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCL 70
FEC+V NPD W + + + S D RL I +D G YT + +
Sbjct: 2593 FECEVA-NPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTYKVAT-- 2649
Query: 71 GKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWD 130
+K++A +L ++ T N V E ++ F + W
Sbjct: 2650 --SKTSA--------KLKVEAVKIKKTLK----NLTVTETQDAVFTVELTHPNVKGVQWI 2695
Query: 131 KDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVIT 188
K+G ++ + + + K I L I +I D +Y LGR ASARL V T
Sbjct: 2696 KNGVVLESNEKYAISVKGTIYS-LRIKNCAIVDESVYGF----RLGRLGASARLHVET 2748
Score = 35.5 bits (78), Expect = 0.15
Identities = 21/79 (26%), Positives = 33/79 (41%), Gaps = 2/79 (2%)
Query: 11 FECQVTGNPDPD--IRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
FEC++T DP + W H + + + G L + D G TC A+N
Sbjct: 1676 FECRLTPISDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATN 1735
Query: 69 CLGKAKSNACLVVYHTRRL 87
G ++A L+V + L
Sbjct: 1736 KYGTDHTSATLIVKDEKSL 1754
Score = 35.5 bits (78), Expect = 0.15
Identities = 21/76 (27%), Positives = 31/76 (40%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G + E V G P P +W + + + D ++ L IK VT +D G Y+
Sbjct: 12416 GKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLT 12475
Query: 66 ASNCLGKAKSNACLVV 81
A N G +VV
Sbjct: 12476 AENSSGTDTQKIKVVV 12491
Score = 35.1 bits (77), Expect = 0.19
Identities = 22/79 (27%), Positives = 35/79 (44%), Gaps = 2/79 (2%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G ++ V+G P P I W + A +++ + + L + +V D G YT E
Sbjct: 22964 GASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTT--ESYSLLIVDKVNRYDAGKYTIE 23021
Query: 66 ASNCLGKAKSNACLVVYHT 84
A N GK + + VY T
Sbjct: 23022 AENQSGKKSATVLVKVYDT 23040
Score = 35.1 bits (77), Expect = 0.19
Identities = 23/82 (28%), Positives = 36/82 (43%), Gaps = 1/82 (1%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDD-GTARLKIKQVTAEDEGTYT 63
+G +V FE +V+G P P ++W + + + E ++ L I+ ED G Y
Sbjct: 25311 EGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYR 25370
Query: 64 CEASNCLGKAKSNACLVVYHTR 85
A+N G A L V R
Sbjct: 25371 VTATNTAGSTSCQAHLQVERLR 25392
Score = 34.7 bits (76), Expect = 0.26
Identities = 19/68 (27%), Positives = 27/68 (39%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G +E VTG P+P I W +++ + + I D GTY E
Sbjct: 7208 GTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIE 7267
Query: 66 ASNCLGKA 73
A N G+A
Sbjct: 7268 AVNVCGRA 7275
Score = 34.7 bits (76), Expect = 0.26
Identities = 25/91 (27%), Positives = 32/91 (35%), Gaps = 5/91 (5%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G TV F + G P P +W I+ + D+ ++ L IK D G Y
Sbjct: 11028 GTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQIT 11087
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAP 96
SN G V H L PG P
Sbjct: 11088 VSNAAGSK-----TVAVHLTVLDVPGPPTGP 11113
Score = 34.7 bits (76), Expect = 0.26
Identities = 22/73 (30%), Positives = 30/73 (41%), Gaps = 3/73 (4%)
Query: 119 VKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRA 178
+KG P P W +D A I E +L + V+ D G Y +TVEN G
Sbjct: 15387 IKGRPDPEVKWARDHGESLDKASI---ESASSYTLLIVGNVNRFDSGKYILTVENSSGSK 15443
Query: 179 EASARLEVITRSG 191
A + V+ G
Sbjct: 15444 SAFVNVRVLDTPG 15456
Score = 34.7 bits (76), Expect = 0.26
Identities = 22/71 (30%), Positives = 31/71 (43%), Gaps = 1/71 (1%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
V G NV + KG P P SW KDG + S + + E + L I E G
Sbjct: 21078 VRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKI-TLSIKNAKKEHGGK 21136
Query: 167 YRITVENELGR 177
Y + ++N + R
Sbjct: 21137 YTVILDNAVCR 21147
Score = 34.3 bits (75), Expect = 0.34
Identities = 38/174 (21%), Positives = 69/174 (39%), Gaps = 19/174 (10%)
Query: 7 DTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEA 66
D F CQ++ +++W+ I++ ++ D RL IK +DE Y C
Sbjct: 6341 DDAVFSCQLS-REKANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKDCRLDDECEYACGV 6399
Query: 67 SNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVE-EGENVTFKCAVKGNPSP 125
+ KS A L V + P P ++E G +V F A
Sbjct: 6400 ED----RKSRARLFV-----------EEIPVEIIRPPQDILEAPGADVVF-LAELNKDKV 6443
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAE 179
W ++ ++ + + + +I R L+I ++ D G YR +++ RA+
Sbjct: 6444 EVQWLRNNMVVVQGDKHQMMSEGKIHR-LQICDIKPRDQGEYRFIAKDKEARAK 6496
Score = 34.3 bits (75), Expect = 0.34
Identities = 16/67 (23%), Positives = 27/67 (40%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
GD ++ E V G P P + W ++++ + L I + D G Y
Sbjct: 14583 GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLT 14642
Query: 66 ASNCLGK 72
A N +G+
Sbjct: 14643 ARNIVGE 14649
Score = 34.3 bits (75), Expect = 0.34
Identities = 20/86 (23%), Positives = 37/86 (43%), Gaps = 3/86 (3%)
Query: 106 VVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVG 165
+V+ G + T +G P P W K + + A + + L I+ + D G
Sbjct: 19700 IVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRAYVDTTDSR---TSLTIENANRNDSG 19756
Query: 166 IYRITVENELGRAEASARLEVITRSG 191
Y +T++N L A + ++V+ G
Sbjct: 19757 KYTLTIQNVLSAASLTLVVKVLDTPG 19782
Score = 33.5 bits (73), Expect = 0.59
Identities = 36/161 (22%), Positives = 61/161 (37%), Gaps = 17/161 (10%)
Query: 7 DTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEA 66
+ FEC+++ + ++WF I+ ++ L I + +DE Y+CE
Sbjct: 5892 EMARFECELS-RENAKVKWFKDGAEIKKGKKYDIISKGAVRILVINKCLLDDEAEYSCEV 5950
Query: 67 SNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPW 126
A+++ L V + + + +A N V E + + C V P
Sbjct: 5951 RT----ARTSGMLTVLEEEAVFT--KNLA--------NIEVSETDTIKLVCEV-SKPGAE 5995
Query: 127 ASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIY 167
W K I + R + E RIL I +ED G Y
Sbjct: 5996 VIWYKGDEEIIETGRYEIL-TEGRKRILVIQNAHLEDAGNY 6035
Score = 33.1 bits (72), Expect = 0.78
Identities = 20/62 (32%), Positives = 26/62 (41%), Gaps = 1/62 (1%)
Query: 7 DTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEA 66
D +FEC+V+ P RW + I FE D + IK EDE Y EA
Sbjct: 5358 DEAKFECEVSREPKT-FRWLKGTQEITGDDRFELIKDGTKHSMVIKSAAFEDEAKYMFEA 5416
Query: 67 SN 68
+
Sbjct: 5417 ED 5418
Score = 33.1 bits (72), Expect = 0.78
Identities = 23/85 (27%), Positives = 33/85 (38%), Gaps = 5/85 (5%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVI--RDCADFESSYDDGTARLKIKQVTAEDEGTY 62
+G + C TG P P++ W I ++ F D L I V +D G Y
Sbjct: 26845 EGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLY 26904
Query: 63 TCEASNCLGKAKSNACLVVYHTRRL 87
T N G S++ V H R +
Sbjct: 26905 TLSLGNEFG---SDSATVNIHIRSI 26926
Score = 32.7 bits (71), Expect = 1.0
Identities = 18/76 (23%), Positives = 29/76 (38%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G V + V G P P + W +++ + + L++ V +D G YT
Sbjct: 12813 GTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTIT 12872
Query: 66 ASNCLGKAKSNACLVV 81
A N G + L V
Sbjct: 12873 AENSSGSKSATIKLKV 12888
Score = 32.7 bits (71), Expect = 1.0
Identities = 20/67 (29%), Positives = 29/67 (43%), Gaps = 1/67 (1%)
Query: 6 GDTVEFEC-QVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
GDT+ + G P P W + IR + + ++ L IK T +D G YT
Sbjct: 13896 GDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTI 13955
Query: 65 EASNCLG 71
A+N G
Sbjct: 13956 TATNPFG 13962
Score = 32.7 bits (71), Expect = 1.0
Identities = 20/91 (21%), Positives = 35/91 (38%), Gaps = 5/91 (5%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+ ++ + G P P + W ++ + + + L IK ED G Y +
Sbjct: 15665 GEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVK 15724
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAP 96
+N G+A ++V L PG P
Sbjct: 15725 LTNSAGEAIETLNVIV-----LDKPGPPTGP 15750
Score = 32.3 bits (70), Expect = 1.4
Identities = 16/75 (21%), Positives = 29/75 (38%)
Query: 7 DTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEA 66
+ ++ + G P + W + +++ S L IK+ + ED GTY
Sbjct: 18913 EQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCV 18972
Query: 67 SNCLGKAKSNACLVV 81
SN G ++V
Sbjct: 18973 SNSAGSITVPITIIV 18987
Score = 31.9 bits (69), Expect = 1.8
Identities = 22/86 (25%), Positives = 35/86 (40%), Gaps = 2/86 (2%)
Query: 106 VVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVG 165
+V G + V+G P+P +W K G I R + + M L I + +D G
Sbjct: 12120 IVRAGCPIRLFAIVRGRPAPKVTWRKVG--IDNVVRKGQVDLVDTMAFLVIPNSTRDDSG 12177
Query: 166 IYRITVENELGRAEASARLEVITRSG 191
Y +T+ N G + V+ G
Sbjct: 12178 KYSLTLVNPAGEKAVFVNVRVLDTPG 12203
Score = 31.9 bits (69), Expect = 1.8
Identities = 23/102 (22%), Positives = 43/102 (42%), Gaps = 4/102 (3%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVK-EKEEIMRILEIDEVSIEDVG 165
+ G ++ AV G P P W K + +++++ + +++ + S D G
Sbjct: 22562 IRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRS--DSG 22619
Query: 166 IYRITVENELGRAEASARLEVITRSGKFYGGLRAYSASPRKC 207
Y +TV+N G S ++V+ G G L + KC
Sbjct: 22620 KYTLTVKNASGTKAVSVMVKVLDSPGP-CGKLTVSRVTQEKC 22660
Score = 31.5 bits (68), Expect = 2.4
Identities = 10/32 (31%), Positives = 19/32 (59%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITP 138
V+ G+ + ++ G+P P +W KD ++I P
Sbjct: 8194 VKRGDEIALDASISGSPYPTITWIKDENVIVP 8225
Score = 31.5 bits (68), Expect = 2.4
Identities = 21/79 (26%), Positives = 28/79 (35%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G T+ V G P P I W +RD + D L+ + V D G Y
Sbjct: 13211 GVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILT 13270
Query: 66 ASNCLGKAKSNACLVVYHT 84
N GK + + V T
Sbjct: 13271 LENSCGKKEYTIVVKVLDT 13289
Score = 31.5 bits (68), Expect = 2.4
Identities = 24/86 (27%), Positives = 33/86 (38%), Gaps = 5/86 (5%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G + + V G P+P I W + + C Y A IK D G YT
Sbjct: 22565 GSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLT 22624
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPG 91
N G K+ + +V + L SPG
Sbjct: 22625 VKNASG-TKAVSVMV----KVLDSPG 22645
Score = 31.1 bits (67), Expect = 3.2
Identities = 22/102 (21%), Positives = 39/102 (38%), Gaps = 3/102 (2%)
Query: 106 VVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVG 165
VV G + V G P P +W+ + + A I E I + I G
Sbjct: 10038 VVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATI---ETTAISSSMVIKNCQRSHQG 10094
Query: 166 IYRITVENELGRAEASARLEVITRSGKFYGGLRAYSASPRKC 207
+Y + +NE G + + ++V+ G A++ + C
Sbjct: 10095 VYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESC 10136
Score = 30.7 bits (66), Expect = 4.2
Identities = 15/59 (25%), Positives = 27/59 (45%), Gaps = 1/59 (1%)
Query: 7 DTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
D V +C+++ D ++WF + I+ + D L +K+ D G YTC+
Sbjct: 5536 DEVILQCEIS-KADAPVKWFKDGKEIKPSKNAVIKTDGKKRMLILKKALKSDIGQYTCD 5593
Score = 30.7 bits (66), Expect = 4.2
Identities = 20/68 (29%), Positives = 28/68 (41%), Gaps = 6/68 (8%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCA--DFESSYDDGTARLKIKQVTAEDEGTYT 63
G ++ + G P P+++W IRD A D SS+ L + V D G YT
Sbjct: 16460 GGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSF----TSLVLDNVNRYDSGKYT 16515
Query: 64 CEASNCLG 71
N G
Sbjct: 16516 LTLENSSG 16523
Score = 30.7 bits (66), Expect = 4.2
Identities = 16/75 (21%), Positives = 31/75 (41%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G ++ E ++G P P I W ++ + L IK+ +D G Y
Sbjct: 16747 GQDLKMEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGIT 16806
Query: 66 ASNCLGKAKSNACLV 80
+N +G+ ++ +V
Sbjct: 16807 VANVVGQKTASIEIV 16821
Score = 30.3 bits (65), Expect = 5.5
Identities = 22/84 (26%), Positives = 37/84 (44%), Gaps = 6/84 (7%)
Query: 109 EGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYR 168
E + V +C + +P W KDG I PS +K + R+L + + D+G Y
Sbjct: 5534 EKDEVILQCEISKADAP-VKWFKDGKEIKPSKNAVIKTDGK-KRMLILKKALKSDIGQYT 5591
Query: 169 ITVENELGRAEASARLEVITRSGK 192
+ G + S +L++ R K
Sbjct: 5592 C----DCGTDKTSGKLDIEDREIK 5611
Score = 30.3 bits (65), Expect = 5.5
Identities = 20/71 (28%), Positives = 29/71 (40%), Gaps = 2/71 (2%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRD-CADFESSYDDGTARLKIKQVTAEDEGTYTC 64
G+T E + G P PD+ W + + + A E L +K D G Y
Sbjct: 18225 GETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYIL 18284
Query: 65 EASNCLGKAKS 75
+ SN +G KS
Sbjct: 18285 KLSN-VGGTKS 18294
Score = 30.3 bits (65), Expect = 5.5
Identities = 17/64 (26%), Positives = 26/64 (40%), Gaps = 2/64 (3%)
Query: 8 TVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEAS 67
T+ + G P+P+++W ++ D A E + L I VT D G Y
Sbjct: 18627 TLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVT--SSFTMLVIDNVTRFDSGRYNLTLE 18684
Query: 68 NCLG 71
N G
Sbjct: 18685 NNSG 18688
Score = 30.3 bits (65), Expect = 5.5
Identities = 22/91 (24%), Positives = 30/91 (32%), Gaps = 5/91 (5%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+ ++ + G P P I W I + A E D L +K D G Y
Sbjct: 19307 GEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLT 19366
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAP 96
N G V + + L PG P
Sbjct: 19367 LKNVAGTRS-----VAVNCKVLDKPGPPAGP 19392
Score = 29.9 bits (64), Expect = 7.3
Identities = 28/99 (28%), Positives = 38/99 (38%), Gaps = 12/99 (12%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCAD---FESSYD----DGTARLKIKQVTAE 57
+G V ++ G P P + WF D + +++ + D T L I Q
Sbjct: 9633 EGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRS 9692
Query: 58 DEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAP 96
D G YT A N LG A L V L PG + P
Sbjct: 9693 DTGLYTITAVNNLGTASKEMRLNV-----LGRPGPPVGP 9726
Score = 29.9 bits (64), Expect = 7.3
Identities = 17/65 (26%), Positives = 22/65 (33%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G V E G P P I W +++ S + L IK E G YT
Sbjct: 21081 GHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVI 21140
Query: 66 ASNCL 70
N +
Sbjct: 21141 LDNAV 21145
Score = 29.5 bits (63), Expect = 9.6
Identities = 18/77 (23%), Positives = 30/77 (38%), Gaps = 1/77 (1%)
Query: 113 VTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVE 172
+T G P P A+W ++ R+ +K ++ I D GIY + +E
Sbjct: 6915 ITILVPSTGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELV-ISPSERSDKGIYTLKLE 6973
Query: 173 NELGRAEASARLEVITR 189
N + + VI R
Sbjct: 6974 NRVKTISGEIDVNVIAR 6990
>BC070170-1|AAH70170.1| 637|Homo sapiens TTN protein protein.
Length = 637
Score = 87.4 bits (207), Expect = 3e-17
Identities = 57/184 (30%), Positives = 92/184 (50%), Gaps = 11/184 (5%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCA--DFESSYDDGTARLKIKQVTAEDEGTY 62
+G T FE ++G P P++ WF +VI + S+ DG A+L I VT + G Y
Sbjct: 19 EGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKANSGRY 78
Query: 63 TCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGN 122
+ +A+N G+A S A L+V + ++P P F + V +G V + V G
Sbjct: 79 SLKATNGSGQATSTAELLV---KAETAP-----PNFVQRLQSMTVRQGSQVRLQVRVTGI 130
Query: 123 PSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASA 182
P+P + +DG+ I S + ++ ++ +L I E ED G Y + N +GRA ++A
Sbjct: 131 PTPVVKFYRDGAEIQSSLDFQISQEGDLYSLL-IAEAYPEDSGTYSVNATNSVGRATSTA 189
Query: 183 RLEV 186
L V
Sbjct: 190 ELLV 193
Score = 46.8 bits (106), Expect = 6e-05
Identities = 34/94 (36%), Positives = 46/94 (48%), Gaps = 3/94 (3%)
Query: 95 APTFYTYPFNKVVE-EGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRI 153
APTF T P VV EG TF+ + G P P SW +DG +I+ S V+ R
Sbjct: 5 APTF-TQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRA 63
Query: 154 -LEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
L I V+ + G Y + N G+A ++A L V
Sbjct: 64 KLTIPAVTKANSGRYSLKATNGSGQATSTAELLV 97
>BC058824-1|AAH58824.1| 558|Homo sapiens TTN protein protein.
Length = 558
Score = 87.4 bits (207), Expect = 3e-17
Identities = 57/184 (30%), Positives = 92/184 (50%), Gaps = 11/184 (5%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCA--DFESSYDDGTARLKIKQVTAEDEGTY 62
+G T FE ++G P P++ WF +VI + S+ DG A+L I VT + G Y
Sbjct: 19 EGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKANSGRY 78
Query: 63 TCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGN 122
+ +A+N G+A S A L+V + ++P P F + V +G V + V G
Sbjct: 79 SLKATNGSGQATSTAELLV---KAETAP-----PNFVQRLQSMTVRQGSQVRLQVRVTGI 130
Query: 123 PSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASA 182
P+P + +DG+ I S + ++ ++ +L I E ED G Y + N +GRA ++A
Sbjct: 131 PTPVVKFYRDGAEIQSSLDFQISQEGDLYSLL-IAEAYPEDSGTYSVNATNSVGRATSTA 189
Query: 183 RLEV 186
L V
Sbjct: 190 ELLV 193
Score = 46.8 bits (106), Expect = 6e-05
Identities = 34/94 (36%), Positives = 46/94 (48%), Gaps = 3/94 (3%)
Query: 95 APTFYTYPFNKVVE-EGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRI 153
APTF T P VV EG TF+ + G P P SW +DG +I+ S V+ R
Sbjct: 5 APTF-TQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRA 63
Query: 154 -LEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
L I V+ + G Y + N G+A ++A L V
Sbjct: 64 KLTIPAVTKANSGRYSLKATNGSGQATSTAELLV 97
>BC013396-1|AAH13396.1| 305|Homo sapiens TTN protein protein.
Length = 305
Score = 87.4 bits (207), Expect = 3e-17
Identities = 57/184 (30%), Positives = 92/184 (50%), Gaps = 11/184 (5%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCA--DFESSYDDGTARLKIKQVTAEDEGTY 62
+G T FE ++G P P++ WF +VI + S+ DG A+L I VT + G Y
Sbjct: 19 EGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKANSGRY 78
Query: 63 TCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGN 122
+ +A+N G+A S A L+V + ++P P F + V +G V + V G
Sbjct: 79 SLKATNGSGQATSTAELLV---KAETAP-----PNFVQRLQSMTVRQGSQVRLQVRVTGI 130
Query: 123 PSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASA 182
P+P + +DG+ I S + ++ ++ +L I E ED G Y + N +GRA ++A
Sbjct: 131 PTPVVKFYRDGAEIQSSLDFQISQEGDLYSLL-IAEAYPEDSGTYSVNATNSVGRATSTA 189
Query: 183 RLEV 186
L V
Sbjct: 190 ELLV 193
Score = 46.8 bits (106), Expect = 6e-05
Identities = 34/94 (36%), Positives = 46/94 (48%), Gaps = 3/94 (3%)
Query: 95 APTFYTYPFNKVVE-EGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRI 153
APTF T P VV EG TF+ + G P P SW +DG +I+ S V+ R
Sbjct: 5 APTF-TQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRA 63
Query: 154 -LEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
L I V+ + G Y + N G+A ++A L V
Sbjct: 64 KLTIPAVTKANSGRYSLKATNGSGQATSTAELLV 97
>AJ277892-3|CAD12457.1| 5604|Homo sapiens Novex-3 Titin Isoform
protein.
Length = 5604
Score = 87.4 bits (207), Expect = 3e-17
Identities = 57/184 (30%), Positives = 92/184 (50%), Gaps = 11/184 (5%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCA--DFESSYDDGTARLKIKQVTAEDEGTY 62
+G T FE ++G P P++ WF +VI + S+ DG A+L I VT + G Y
Sbjct: 19 EGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKANSGRY 78
Query: 63 TCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGN 122
+ +A+N G+A S A L+V + ++P P F + V +G V + V G
Sbjct: 79 SLKATNGSGQATSTAELLV---KAETAP-----PNFVQRLQSMTVRQGSQVRLQVRVTGI 130
Query: 123 PSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASA 182
P+P + +DG+ I S + ++ ++ +L I E ED G Y + N +GRA ++A
Sbjct: 131 PTPVVKFYRDGAEIQSSLDFQISQEGDLYSLL-IAEAYPEDSGTYSVNATNSVGRATSTA 189
Query: 183 RLEV 186
L V
Sbjct: 190 ELLV 193
Score = 77.0 bits (181), Expect = 5e-14
Identities = 52/184 (28%), Positives = 79/184 (42%), Gaps = 8/184 (4%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAE-VIRDCADFESSYDDGTARLKIKQVTAEDEGTYT 63
+G T F+ +V G P P+ WFH + ++ D +DGT L I T D G +T
Sbjct: 1470 EGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWT 1529
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
A N G++ + L V + Q+ P F N ++EG + K GNP
Sbjct: 1530 VVAQNRAGRSSISVILTV------EAVEHQVKPMFVEKLKNVNIKEGSQLEMKVRATGNP 1583
Query: 124 SPWASWDKDGSIITPSARITVK-EKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASA 182
+P W K+ II P ++ E + L+ID +D Y T N+ GR
Sbjct: 1584 NPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRC 1643
Query: 183 RLEV 186
++ V
Sbjct: 1644 KVNV 1647
Score = 73.3 bits (172), Expect = 6e-13
Identities = 52/184 (28%), Positives = 79/184 (42%), Gaps = 6/184 (3%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G F ++G P P I W+ +++ + +D L + + ED YTCE
Sbjct: 3253 GKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCE 3312
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQM---APTFYTYPFNKVVEEGENVTFKCAVKGN 122
A N G A ++A L V + SP ++M P T + V EG+ F+C V G
Sbjct: 3313 AKNDYGVATTSASLSV-EVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGT 3371
Query: 123 PSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASA 182
SW I PS + + E+ + LEI E ED G Y N +G+ ++A
Sbjct: 3372 DLK-VSWYSKDKKIKPSRFFRMTQFEDTYQ-LEIAEAYPEDEGTYTFVASNAVGQVSSTA 3429
Query: 183 RLEV 186
L +
Sbjct: 3430 NLSL 3433
Score = 64.9 bits (151), Expect = 2e-10
Identities = 27/77 (35%), Positives = 42/77 (54%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G++V EC ++G P P + W+ I DF+ ++ G ARL I++ AED G +TC
Sbjct: 956 EGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTC 1015
Query: 65 EASNCLGKAKSNACLVV 81
A N G ++ L V
Sbjct: 1016 SAVNEAGTVSTSCYLAV 1032
Score = 62.9 bits (146), Expect = 8e-10
Identities = 37/102 (36%), Positives = 46/102 (45%), Gaps = 1/102 (0%)
Query: 84 TRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARIT 143
T + PG AP F T P + + EG +V F C V GNP P W K G +T R
Sbjct: 1070 TEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYK 1129
Query: 144 VKEKEEIMRI-LEIDEVSIEDVGIYRITVENELGRAEASARL 184
V ++ L I +D G Y I V N+ G ASA L
Sbjct: 1130 VSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1171
Score = 54.8 bits (126), Expect = 2e-07
Identities = 35/128 (27%), Positives = 63/128 (49%), Gaps = 4/128 (3%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+GD++ EC ++G P P + WF +++ F+ + + +L IK V ++D G Y C
Sbjct: 4172 EGDSIILECLISGEPQPVVTWFQNGVLLKQNQKFQFEEVNCSHQLYIKDVNSQDSGKYKC 4231
Query: 65 EASNCLGKAKSNACLVVYH-TRRLSSPGRQMAPTFYTYPFN-KVVEEGENVT--FKCAVK 120
A N G +S + L V T R +S + + Y + ++ ++GE+V F
Sbjct: 4232 VAENNSGAVESVSDLTVEPVTYRENSQFENIGEIYGKYSRDQQLQDQGESVRAHFYDYPA 4291
Query: 121 GNPSPWAS 128
G +PW +
Sbjct: 4292 GPFTPWTN 4299
Score = 54.0 bits (124), Expect = 4e-07
Identities = 24/64 (37%), Positives = 36/64 (56%), Gaps = 1/64 (1%)
Query: 11 FECQVTGNPDPDIRWF-HYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNC 69
F+C V G P P+++W+ Y + D + S + G+ LKI+ V D TY C A NC
Sbjct: 5399 FKCSVIGIPTPEVKWYKEYMCIEPDNIKYVISEEKGSHTLKIRNVCLSDSATYRCRAVNC 5458
Query: 70 LGKA 73
+G+A
Sbjct: 5459 VGEA 5462
Score = 53.6 bits (123), Expect = 5e-07
Identities = 31/87 (35%), Positives = 44/87 (50%), Gaps = 1/87 (1%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSY-DDGTARLKIKQVTAEDEGTYT 63
+G V F C+++G P P I W+ + I+ ++ + DG A L+I V EDEG YT
Sbjct: 1304 EGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYT 1363
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSP 90
ASN G A + L V L +P
Sbjct: 1364 AFASNIKGNAICSGKLYVEPAAPLGAP 1390
Score = 53.2 bits (122), Expect = 7e-07
Identities = 46/173 (26%), Positives = 70/173 (40%), Gaps = 16/173 (9%)
Query: 6 GDTVEFECQVTGNPDPDIRWF-HYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
G F +V G PDP+ W+ + ++ R + +D L I+ VTAED +
Sbjct: 2092 GSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMV 2151
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVV--EEGENVTFKCAVKGN 122
+A N G+ S+A L+V + ++ +T VV E+ TF+C
Sbjct: 2152 KAINIAGETSSHAFLLVQAKQLIT----------FTQELQDVVAKEKDTMATFECET-SE 2200
Query: 123 PSPWASWDKDGSII--TPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVEN 173
P W KDG + R+ K + IL ID ED + EN
Sbjct: 2201 PFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVEDEN 2253
Score = 52.8 bits (121), Expect = 9e-07
Identities = 31/94 (32%), Positives = 44/94 (46%), Gaps = 2/94 (2%)
Query: 96 PTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILE 155
P YP V EGE F+C V G P P +W +G +I S R V + + + L+
Sbjct: 1841 PDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRV--RYDGIHYLD 1898
Query: 156 IDEVSIEDVGIYRITVENELGRAEASARLEVITR 189
I + D G ++T EN G E +LE+ R
Sbjct: 1899 IVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQR 1932
Score = 49.6 bits (113), Expect = 8e-06
Identities = 30/91 (32%), Positives = 43/91 (47%), Gaps = 1/91 (1%)
Query: 96 PTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILE 155
PT + N V EGE+VT +C + G PSP +W ++ I S + + I R++
Sbjct: 943 PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLM- 1001
Query: 156 IDEVSIEDVGIYRITVENELGRAEASARLEV 186
I E ED G + + NE G S L V
Sbjct: 1002 IREAFAEDSGRFTCSAVNEAGTVSTSCYLAV 1032
Score = 48.0 bits (109), Expect = 3e-05
Identities = 28/81 (34%), Positives = 41/81 (50%), Gaps = 4/81 (4%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVI----RDCADFESSYDDGTARLKIKQVTAEDEG 60
+G+ V F C++ P P++ WFH I R ES ++ L+IK+V D G
Sbjct: 3517 EGEPVVFTCRLIACPTPEMTWFHNNRPIPTGLRRIIKAESDLHHHSSSLEIKRVQDRDSG 3576
Query: 61 TYTCEASNCLGKAKSNACLVV 81
+Y A N G A+S A L+V
Sbjct: 3577 SYRLLAINSEGSAESTASLLV 3597
Score = 47.6 bits (108), Expect = 3e-05
Identities = 30/83 (36%), Positives = 37/83 (44%)
Query: 104 NKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIED 163
N + EG VTF C + G P P +W KDG I R + ++ L I V ED
Sbjct: 1299 NYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPED 1358
Query: 164 VGIYRITVENELGRAEASARLEV 186
GIY N G A S +L V
Sbjct: 1359 EGIYTAFASNIKGNAICSGKLYV 1381
Score = 46.8 bits (106), Expect = 6e-05
Identities = 34/94 (36%), Positives = 46/94 (48%), Gaps = 3/94 (3%)
Query: 95 APTFYTYPFNKVVE-EGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRI 153
APTF T P VV EG TF+ + G P P SW +DG +I+ S V+ R
Sbjct: 5 APTF-TQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRA 63
Query: 154 -LEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
L I V+ + G Y + N G+A ++A L V
Sbjct: 64 KLTIPAVTKANSGRYSLKATNGSGQATSTAELLV 97
Score = 46.8 bits (106), Expect = 6e-05
Identities = 32/97 (32%), Positives = 45/97 (46%), Gaps = 3/97 (3%)
Query: 96 PTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMR--- 152
P+F K V EGE V F C + P+P +W + I R +K + ++
Sbjct: 3504 PSFTQKLTFKYVLEGEPVVFTCRLIACPTPEMTWFHNNRPIPTGLRRIIKAESDLHHHSS 3563
Query: 153 ILEIDEVSIEDVGIYRITVENELGRAEASARLEVITR 189
LEI V D G YR+ N G AE++A L VI +
Sbjct: 3564 SLEIKRVQDRDSGSYRLLAINSEGSAESTASLLVIQK 3600
Score = 44.8 bits (101), Expect = 2e-04
Identities = 25/78 (32%), Positives = 38/78 (48%), Gaps = 2/78 (2%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYD--DGTARLKIKQVTAEDEGTY 62
+G +V F CQV GNP P + W + ++ SY+ G +L I A+D G Y
Sbjct: 1095 EGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEY 1154
Query: 63 TCEASNCLGKAKSNACLV 80
T N G+ ++A L+
Sbjct: 1155 TIVVRNKHGETSASASLL 1172
Score = 44.8 bits (101), Expect = 2e-04
Identities = 31/112 (27%), Positives = 46/112 (41%), Gaps = 4/112 (3%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G+T F C+VTG P P + W+ ++IR F Y DG L I + D G
Sbjct: 1854 EGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRY-DGIHYLDIVDCKSYDTGEVKV 1912
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGR---QMAPTFYTYPFNKVVEEGENV 113
A N G + L + S R + P F+ + K+ E + V
Sbjct: 1913 TAENPEGVIEHKVKLEIQQREDFRSVLRRAPEPRPEFHVHEPGKLQFEVQKV 1964
Score = 44.8 bits (101), Expect = 2e-04
Identities = 21/78 (26%), Positives = 40/78 (51%), Gaps = 1/78 (1%)
Query: 109 EGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYR 168
EG+++ +C + G P P +W ++G ++ + + E+ L I +V+ +D G Y+
Sbjct: 4172 EGDSIILECLISGEPQPVVTWFQNGVLLKQNQKFQF-EEVNCSHQLYIKDVNSQDSGKYK 4230
Query: 169 ITVENELGRAEASARLEV 186
EN G E+ + L V
Sbjct: 4231 CVAENNSGAVESVSDLTV 4248
Score = 44.8 bits (101), Expect = 2e-04
Identities = 23/76 (30%), Positives = 35/76 (46%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G F+C V G+P P + W+ ++++ G L I + DEG Y C
Sbjct: 5528 GTAAYFQCLVRGSPRPTVYWYKDGKLVQGRRFTVEESGTGFHNLFITSLVKSDEGEYRCV 5587
Query: 66 ASNCLGKAKSNACLVV 81
A+N G A+S A L +
Sbjct: 5588 ATNKSGMAESFAALTL 5603
Score = 43.2 bits (97), Expect = 7e-04
Identities = 26/86 (30%), Positives = 38/86 (44%)
Query: 93 QMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMR 152
+M P F + + E + FKC+V G P+P W K+ I P V +E+
Sbjct: 5377 EMPPRFIMPICDFKIPENSDAVFKCSVIGIPTPEVKWYKEYMCIEPDNIKYVISEEKGSH 5436
Query: 153 ILEIDEVSIEDVGIYRITVENELGRA 178
L+I V + D YR N +G A
Sbjct: 5437 TLKIRNVCLSDSATYRCRAVNCVGEA 5462
Score = 41.1 bits (92), Expect = 0.003
Identities = 24/95 (25%), Positives = 45/95 (47%), Gaps = 1/95 (1%)
Query: 93 QMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMR 152
+M P+F + V E + F V+G P P W ++ S++ P RI ++ +
Sbjct: 5180 EMPPSFIEPLTKRKVYENTTLGFIVEVEGLPVPGVKWYRNKSLLEPDERIKMERVGNVCS 5239
Query: 153 ILEIDEVSIEDVGIYRITVENELGRAEASARLEVI 187
LEI + + G Y N +G A++ A ++++
Sbjct: 5240 -LEISNIQKGEGGEYMCHAVNIIGEAKSFANVDIM 5273
Score = 40.7 bits (91), Expect = 0.004
Identities = 28/95 (29%), Positives = 37/95 (38%)
Query: 92 RQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIM 151
R P F P + EG+ F V G P P W DG I V KE+
Sbjct: 1453 RLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGT 1512
Query: 152 RILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
+ L I + D G + + +N GR+ S L V
Sbjct: 1513 QSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTV 1547
Score = 39.9 bits (89), Expect = 0.007
Identities = 24/97 (24%), Positives = 43/97 (44%), Gaps = 1/97 (1%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+GD+ F C G P P + W++ I +F + + L + V ++EG+ TC
Sbjct: 3957 EGDSCNFVCHFQGYPQPIVTWYNNDMPIPRNQNFIIHSLENYSILTLSSVHHQNEGSITC 4016
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTY 101
N G K+ + L V ++ ++ P F+ Y
Sbjct: 4017 VLFNQYGTVKTTSMLKVKAKQKHDVKAHKV-PVFHDY 4052
Score = 39.5 bits (88), Expect = 0.009
Identities = 19/73 (26%), Positives = 33/73 (45%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+ T+ F +V G P P ++W+ ++ + L+I + + G Y C
Sbjct: 5196 ENTTLGFIVEVEGLPVPGVKWYRNKSLLEPDERIKMERVGNVCSLEISNIQKGEGGEYMC 5255
Query: 65 EASNCLGKAKSNA 77
A N +G+AKS A
Sbjct: 5256 HAVNIIGEAKSFA 5268
Score = 38.3 bits (85), Expect = 0.021
Identities = 22/80 (27%), Positives = 35/80 (43%), Gaps = 1/80 (1%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
V+ G+ F + G P P SW K+ +++ + + +L I E ED +
Sbjct: 3250 VQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLI-EAFPEDAAV 3308
Query: 167 YRITVENELGRAEASARLEV 186
Y +N+ G A SA L V
Sbjct: 3309 YTCEAKNDYGVATTSASLSV 3328
Score = 37.9 bits (84), Expect = 0.027
Identities = 29/98 (29%), Positives = 43/98 (43%), Gaps = 1/98 (1%)
Query: 89 SPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKE 148
SP + AP + ++ V +G + F+ V G P P W K+G I S RI E
Sbjct: 2072 SPSME-APKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPE 2130
Query: 149 EIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
+ + L I +V+ ED + N G + A L V
Sbjct: 2131 DNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLV 2168
Score = 36.7 bits (81), Expect = 0.063
Identities = 40/162 (24%), Positives = 69/162 (42%), Gaps = 17/162 (10%)
Query: 10 EFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNC 69
E EC V+ + + +W+H ++ + + G L +K VT ED+G Y+
Sbjct: 2285 ELECIVSPE-NIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVID-- 2341
Query: 70 LGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASW 129
K C +L R +A ++ V EG+ V + V S W
Sbjct: 2342 ---GKKTTC-------KLKMKPRPIA--ILQGLSDQKVCEGDIVQLEVKV-SLESVEGVW 2388
Query: 130 DKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITV 171
KDG + PS R+ + ++ +L I++++ ED G Y T+
Sbjct: 2389 MKDGQEVQPSDRVHIVIDKQ-SHMLLIEDMTKEDAGNYSFTI 2429
Score = 36.3 bits (80), Expect = 0.084
Identities = 21/79 (26%), Positives = 34/79 (43%), Gaps = 2/79 (2%)
Query: 11 FECQVT--GNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
FEC++T G+P + W H + + + G L + D G TC A+N
Sbjct: 1722 FECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATN 1781
Query: 69 CLGKAKSNACLVVYHTRRL 87
G ++A L+V + L
Sbjct: 1782 KYGTDHTSATLIVKDEKSL 1800
Score = 35.9 bits (79), Expect = 0.11
Identities = 45/178 (25%), Positives = 69/178 (38%), Gaps = 22/178 (12%)
Query: 11 FECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCL 70
FEC+V NPD W + + + S D RL I +D G YT + +
Sbjct: 2639 FECEVA-NPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTYKVAT-- 2695
Query: 71 GKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWD 130
+K++A +L ++ T N V E ++ F + W
Sbjct: 2696 --SKTSA--------KLKVEAVKIKKTLK----NLTVTETQDAVFTVELTHPNVKGVQWI 2741
Query: 131 KDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVIT 188
K+G ++ + + + K I L I +I D +Y LGR ASARL V T
Sbjct: 2742 KNGVVLESNEKYAISVKGTIYS-LRIKNCAIVDESVYGF----RLGRLGASARLHVET 2794
Score = 33.9 bits (74), Expect = 0.45
Identities = 21/91 (23%), Positives = 40/91 (43%), Gaps = 1/91 (1%)
Query: 96 PTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILE 155
P+F ++ V EG++ F C +G P P +W + I + + E IL
Sbjct: 3944 PSFLQEIESQEVYEGDSCNFVCHFQGYPQPIVTWYNNDMPIPRNQNFIIHSLEN-YSILT 4002
Query: 156 IDEVSIEDVGIYRITVENELGRAEASARLEV 186
+ V ++ G + N+ G + ++ L+V
Sbjct: 4003 LSSVHHQNEGSITCVLFNQYGTVKTTSMLKV 4033
>AJ277892-1|CAD12455.1|26926|Homo sapiens N2B-Titin Isoform protein.
Length = 26926
Score = 87.4 bits (207), Expect = 3e-17
Identities = 57/184 (30%), Positives = 92/184 (50%), Gaps = 11/184 (5%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCA--DFESSYDDGTARLKIKQVTAEDEGTY 62
+G T FE ++G P P++ WF +VI + S+ DG A+L I VT + G Y
Sbjct: 19 EGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKANSGRY 78
Query: 63 TCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGN 122
+ +A+N G+A S A L+V + ++P P F + V +G V + V G
Sbjct: 79 SLKATNGSGQATSTAELLV---KAETAP-----PNFVQRLQSMTVRQGSQVRLQVRVTGI 130
Query: 123 PSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASA 182
P+P + +DG+ I S + ++ ++ +L I E ED G Y + N +GRA ++A
Sbjct: 131 PTPVVKFYRDGAEIQSSLDFQISQEGDLYSLL-IAEAYPEDSGTYSVNATNSVGRATSTA 189
Query: 183 RLEV 186
L V
Sbjct: 190 ELLV 193
Score = 86.6 bits (205), Expect = 6e-17
Identities = 55/185 (29%), Positives = 81/185 (43%), Gaps = 7/185 (3%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSY----DDGTARLKIKQVTAEDEGT 61
G+ V F +T +P+P + W+ + I+ D + Y D G +L I VT +D+
Sbjct: 25207 GENVRFGVTITVHPEPHVTWYKSGQKIKP-GDNDKKYTFESDKGLYQLTINSVTTDDDAE 25265
Query: 62 YTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKG 121
YT A N G+ A L V T + P F N +EG++V F+ V G
Sbjct: 25266 YTVVARNKYGEDSCKAKLTV--TLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSG 25323
Query: 122 NPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEAS 181
P P W+KDG ++ I + + L I + ED G YR+T N G
Sbjct: 25324 IPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQ 25383
Query: 182 ARLEV 186
A L+V
Sbjct: 25384 AHLQV 25388
Score = 78.6 bits (185), Expect = 2e-14
Identities = 48/166 (28%), Positives = 77/166 (46%), Gaps = 8/166 (4%)
Query: 22 DIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLGKAKSNACLVV 81
D++W + + ++ L IKQ + DEG TC + G K L +
Sbjct: 26570 DVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTL 26629
Query: 82 YHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSAR 141
++ LS AP F + P ++ + EG+NV F C + G PSP W K+ I+ S+
Sbjct: 26630 --SKELSD-----APAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSN 26682
Query: 142 ITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVI 187
+++ + LEI S+ D G Y I +N G+ A+A L V+
Sbjct: 26683 VSISRSRNVYS-LEIRNASVSDSGKYTIKAKNFRGQCSATASLMVL 26727
Score = 77.4 bits (182), Expect = 4e-14
Identities = 54/202 (26%), Positives = 91/202 (45%), Gaps = 20/202 (9%)
Query: 5 DGDTVEFECQVTG-NPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYT 63
+G V++ C++ + + W+ + + +E +Y+DG A L +K +T D+GTY
Sbjct: 25084 EGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYR 25143
Query: 64 CEASNCLGKAKSNACLVV--------YHTRRLSSPGRQMAPTF--------YTYP-FNKV 106
C+ N G+ S A L V Y+ RR ++ T +T P +NK
Sbjct: 25144 CKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNKT 25203
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITP--SARITVKEKEEIMRILEIDEVSIEDV 164
GENV F + +P P +W K G I P + + E ++ + L I+ V+ +D
Sbjct: 25204 AYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDD 25263
Query: 165 GIYRITVENELGRAEASARLEV 186
Y + N+ G A+L V
Sbjct: 25264 AEYTVVARNKYGEDSCKAKLTV 25285
Score = 77.0 bits (181), Expect = 5e-14
Identities = 52/184 (28%), Positives = 79/184 (42%), Gaps = 8/184 (4%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAE-VIRDCADFESSYDDGTARLKIKQVTAEDEGTYT 63
+G T F+ +V G P P+ WFH + ++ D +DGT L I T D G +T
Sbjct: 1424 EGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWT 1483
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
A N G++ + L V + Q+ P F N ++EG + K GNP
Sbjct: 1484 VVAQNRAGRSSISVILTV------EAVEHQVKPMFVEKLKNVNIKEGSQLEMKVRATGNP 1537
Query: 124 SPWASWDKDGSIITPSARITVK-EKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASA 182
+P W K+ II P ++ E + L+ID +D Y T N+ GR
Sbjct: 1538 NPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRC 1597
Query: 183 RLEV 186
++ V
Sbjct: 1598 KVNV 1601
Score = 76.6 bits (180), Expect = 6e-14
Identities = 44/187 (23%), Positives = 83/187 (44%), Gaps = 8/187 (4%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+ + CQ+ G P PDI+W+ + + + ++ S D T L + EDEG YTC
Sbjct: 24050 GEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCI 24109
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A+N +G+ ++++ L++ T + PG + +Y G + G P P
Sbjct: 24110 ATNEVGEVETSSKLLLQATPQF-HPGYPLKEKYYG-------AVGSTLRLHVMYIGRPVP 24161
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
+W ++ S IT++ E ++ + G Y++ + N G +A +E
Sbjct: 24162 AMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVE 24221
Query: 186 VITRSGK 192
+ + K
Sbjct: 24222 IQDKPDK 24228
Score = 73.3 bits (172), Expect = 6e-13
Identities = 52/184 (28%), Positives = 79/184 (42%), Gaps = 6/184 (3%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G F ++G P P I W+ +++ + +D L + + ED YTCE
Sbjct: 3207 GKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCE 3266
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQM---APTFYTYPFNKVVEEGENVTFKCAVKGN 122
A N G A ++A L V + SP ++M P T + V EG+ F+C V G
Sbjct: 3267 AKNDYGVATTSASLSV-EVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGT 3325
Query: 123 PSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASA 182
SW I PS + + E+ + LEI E ED G Y N +G+ ++A
Sbjct: 3326 DLK-VSWYSKDKKIKPSRFFRMTQFEDTYQ-LEIAEAYPEDEGTYTFVASNAVGQVSSTA 3383
Query: 183 RLEV 186
L +
Sbjct: 3384 NLSL 3387
Score = 68.5 bits (160), Expect = 2e-11
Identities = 53/196 (27%), Positives = 76/196 (38%), Gaps = 14/196 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
GD V G P P I+WF ++ AD++ +D L I EDEG YTC
Sbjct: 3471 GDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCM 3530
Query: 66 ASNCLGKAKSNACLVVYH--------------TRRLSSPGRQMAPTFYTYPFNKVVEEGE 111
ASN GK +A L + + L G P F +G
Sbjct: 3531 ASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGL 3590
Query: 112 NVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITV 171
F+ V G P+P +W K+ + S T+ +++ ED G+Y
Sbjct: 3591 PAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKA 3650
Query: 172 ENELGRAEASARLEVI 187
EN LG + +A L V+
Sbjct: 3651 ENMLGESTCAAELLVL 3666
Score = 64.9 bits (151), Expect = 2e-10
Identities = 27/77 (35%), Positives = 42/77 (54%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G++V EC ++G P P + W+ I DF+ ++ G ARL I++ AED G +TC
Sbjct: 910 EGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTC 969
Query: 65 EASNCLGKAKSNACLVV 81
A N G ++ L V
Sbjct: 970 SAVNEAGTVSTSCYLAV 986
Score = 62.9 bits (146), Expect = 8e-10
Identities = 37/102 (36%), Positives = 46/102 (45%), Gaps = 1/102 (0%)
Query: 84 TRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARIT 143
T + PG AP F T P + + EG +V F C V GNP P W K G +T R
Sbjct: 1024 TEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYK 1083
Query: 144 VKEKEEIMRI-LEIDEVSIEDVGIYRITVENELGRAEASARL 184
V ++ L I +D G Y I V N+ G ASA L
Sbjct: 1084 VSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1125
Score = 62.9 bits (146), Expect = 8e-10
Identities = 36/96 (37%), Positives = 51/96 (53%), Gaps = 1/96 (1%)
Query: 96 PTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILE 155
PT + +V EGE ++ + P P SW KDG + S R+T+K + I LE
Sbjct: 7890 PTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKN-DHISAHLE 7948
Query: 156 IDEVSIEDVGIYRITVENELGRAEASARLEVITRSG 191
+ + D GIY IT+EN+LG A AS ++VI G
Sbjct: 7949 VPKSVRADAGIYTITLENKLGSATASINVKVIGLPG 7984
Score = 62.1 bits (144), Expect = 1e-09
Identities = 51/192 (26%), Positives = 78/192 (40%), Gaps = 13/192 (6%)
Query: 2 LSCDGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAED-EG 60
+S +GD V +T + + W+ +++ F+ D T L I +V ED +G
Sbjct: 4253 VSEEGDIVHLTTSITNAKE--VNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQG 4310
Query: 61 TYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVK 120
Y CEA N GK ++A L V ++ AP V G F C ++
Sbjct: 4311 EYVCEALNDSGKTATSAKLTVV---------KRAAPVIKRKIEPLEVALGHLAKFTCEIQ 4361
Query: 121 GNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEA 180
P+ W K G I S + +++ + I LEI + D G Y NE G
Sbjct: 4362 SAPNVRFQWFKAGREIYESDKCSIRSSKYISS-LEILRTQVVDCGEYTCKASNEYGSVSC 4420
Query: 181 SARLEVITRSGK 192
+A L V G+
Sbjct: 4421 TATLTVTVPGGE 4432
Score = 58.8 bits (136), Expect = 1e-08
Identities = 43/176 (24%), Positives = 72/176 (40%), Gaps = 8/176 (4%)
Query: 13 CQVTGNPDPDIRWFHYA-EVIRDCADFE-SSYDDGTARLKIKQVTAEDEGTYTCEASNCL 70
C+VTG+P P ++W+ E+I D + + G +L I VT +D Y A+N
Sbjct: 24452 CKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQG 24511
Query: 71 GKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWD 130
G A L V ++ P + + + GE V+ K G P P +W
Sbjct: 24512 GSVSGTASLEVEVPAKIHLP-KTLEGMGAVHALR-----GEVVSIKIPFSGKPDPVITWQ 24565
Query: 131 KDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
K +I + V ++ + V +D G Y + +N G + + L+V
Sbjct: 24566 KGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDV 24621
Score = 58.4 bits (135), Expect = 2e-08
Identities = 30/85 (35%), Positives = 46/85 (54%), Gaps = 1/85 (1%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
V+ G NV V G P P SW KDG+++ P+ I + + + LE+ V+ +D G
Sbjct: 12810 VKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLC-TLELFSVNRKDSGD 12868
Query: 167 YRITVENELGRAEASARLEVITRSG 191
Y IT EN G A+ +L+V+ + G
Sbjct: 12869 YTITAENSSGSKSATIKLKVLDKPG 12893
Score = 56.8 bits (131), Expect = 6e-08
Identities = 31/93 (33%), Positives = 43/93 (46%), Gaps = 1/93 (1%)
Query: 94 MAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRI 153
+A T P + V EGE+ F C G P P +W + G +++ SAR V +
Sbjct: 26062 LAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQV-TTTKYKST 26120
Query: 154 LEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
EI V D G Y + VEN G+ EA L +
Sbjct: 26121 FEISSVQASDEGNYSVVVENSEGKQEAEFTLTI 26153
Score = 54.0 bits (124), Expect = 4e-07
Identities = 44/183 (24%), Positives = 81/183 (44%), Gaps = 21/183 (11%)
Query: 7 DTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEA 66
DT++ C+V+ P ++ W+ E I + +E + L I+ ED G Y C
Sbjct: 5981 DTIKLVCEVS-KPGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQNAHLEDAGNYNCR- 6038
Query: 67 SNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPW 126
L ++++ + V+ ++A F + P N + EGE F C++ P
Sbjct: 6039 ---LPSSRTDGKVKVH----------ELAAEFISKPQNLEILEGEKAEFVCSISKESFP- 6084
Query: 127 ASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W +D + + V + R+L + + +++D+G Y + V G A A+A L V
Sbjct: 6085 VQWKRDDKTLESGDKYDVIADGK-KRVLVVKDATLQDMGTYVVMV----GAARAAAHLTV 6139
Query: 187 ITR 189
I +
Sbjct: 6140 IEK 6142
Score = 53.6 bits (123), Expect = 5e-07
Identities = 31/87 (35%), Positives = 44/87 (50%), Gaps = 1/87 (1%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSY-DDGTARLKIKQVTAEDEGTYT 63
+G V F C+++G P P I W+ + I+ ++ + DG A L+I V EDEG YT
Sbjct: 1258 EGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYT 1317
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSP 90
ASN G A + L V L +P
Sbjct: 1318 AFASNIKGNAICSGKLYVEPAAPLGAP 1344
Score = 53.6 bits (123), Expect = 5e-07
Identities = 31/98 (31%), Positives = 49/98 (50%), Gaps = 2/98 (2%)
Query: 102 PFNKV-VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVS 160
PFN ++ GE++ + V G P P SW KDG + + R+ V E+ +L I E +
Sbjct: 17820 PFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNV-EETATSTVLHIKEGN 17878
Query: 161 IEDVGIYRITVENELGRAEASARLEVITRSGKFYGGLR 198
+D G Y +T N G A + + V+ + G G +R
Sbjct: 17879 KDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGPVR 17916
Score = 53.2 bits (122), Expect = 7e-07
Identities = 46/173 (26%), Positives = 70/173 (40%), Gaps = 16/173 (9%)
Query: 6 GDTVEFECQVTGNPDPDIRWF-HYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
G F +V G PDP+ W+ + ++ R + +D L I+ VTAED +
Sbjct: 2046 GSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMV 2105
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVV--EEGENVTFKCAVKGN 122
+A N G+ S+A L+V + ++ +T VV E+ TF+C
Sbjct: 2106 KAINIAGETSSHAFLLVQAKQLIT----------FTQELQDVVAKEKDTMATFECET-SE 2154
Query: 123 PSPWASWDKDGSII--TPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVEN 173
P W KDG + R+ K + IL ID ED + EN
Sbjct: 2155 PFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVEDEN 2207
Score = 53.2 bits (122), Expect = 7e-07
Identities = 32/99 (32%), Positives = 42/99 (42%), Gaps = 1/99 (1%)
Query: 106 VVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVG 165
VV+ G V F ++G P P A W DGS I TV E + +L I D G
Sbjct: 11024 VVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTV-ETDNFSSVLTIKNCLRRDTG 11082
Query: 166 IYRITVENELGRAEASARLEVITRSGKFYGGLRAYSASP 204
Y+ITV N G + L V+ G G + +P
Sbjct: 11083 EYQITVSNAAGSKTVAVHLTVLDVPGPPTGPINILDVTP 11121
Score = 52.8 bits (121), Expect = 9e-07
Identities = 31/94 (32%), Positives = 44/94 (46%), Gaps = 2/94 (2%)
Query: 96 PTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILE 155
P YP V EGE F+C V G P P +W +G +I S R V + + + L+
Sbjct: 1795 PDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRV--RYDGIHYLD 1852
Query: 156 IDEVSIEDVGIYRITVENELGRAEASARLEVITR 189
I + D G ++T EN G E +LE+ R
Sbjct: 1853 IVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQR 1886
Score = 51.6 bits (118), Expect = 2e-06
Identities = 24/77 (31%), Positives = 38/77 (49%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G V F C+++G P P+I WF I ++ S L+I+ + D G YT
Sbjct: 26650 EGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTI 26709
Query: 65 EASNCLGKAKSNACLVV 81
+A N G+ + A L+V
Sbjct: 26710 KAKNFRGQCSATASLMV 26726
Score = 51.2 bits (117), Expect = 3e-06
Identities = 41/146 (28%), Positives = 59/146 (40%), Gaps = 6/146 (4%)
Query: 46 TARLKIKQVTAEDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNK 105
T I +TA +E + A N G++ V R + P F+T FN
Sbjct: 18853 TLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELP-FHT--FN- 18908
Query: 106 VVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVG 165
V+ E + KG P +W KDG + + R+ V + + L I E S EDVG
Sbjct: 18909 -VKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTS-LSIKEASKEDVG 18966
Query: 166 IYRITVENELGRAEASARLEVITRSG 191
Y + V N G + V+ R G
Sbjct: 18967 TYELCVSNSAGSITVPITIIVLDRPG 18992
Score = 50.4 bits (115), Expect = 5e-06
Identities = 30/93 (32%), Positives = 49/93 (52%), Gaps = 7/93 (7%)
Query: 96 PTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILE 155
P F +Y V+ G+++ + + G P P +W KDG + + RI V + + + L
Sbjct: 16737 PAFSSYS----VQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLD-LTTLS 16791
Query: 156 IDEVSIEDVGIYRITVENELGRAEASARLEVIT 188
I E +D G Y ITV N +G+ AS +E++T
Sbjct: 16792 IKETHKDDGGQYGITVANVVGQKTAS--IEIVT 16822
Score = 49.6 bits (113), Expect = 8e-06
Identities = 30/91 (32%), Positives = 43/91 (47%), Gaps = 1/91 (1%)
Query: 96 PTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILE 155
PT + N V EGE+VT +C + G PSP +W ++ I S + + I R++
Sbjct: 897 PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLM- 955
Query: 156 IDEVSIEDVGIYRITVENELGRAEASARLEV 186
I E ED G + + NE G S L V
Sbjct: 956 IREAFAEDSGRFTCSAVNEAGTVSTSCYLAV 986
Score = 49.6 bits (113), Expect = 8e-06
Identities = 27/86 (31%), Positives = 45/86 (52%), Gaps = 3/86 (3%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRI-LEIDEVSIEDVG 165
V G+ + VKG P P +W K+G ++ R+ + +++ R+ L+I E D G
Sbjct: 11423 VRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDL--IQDLPRVELQIKEAVRADHG 11480
Query: 166 IYRITVENELGRAEASARLEVITRSG 191
Y I+ +N G A+ SA + V+ R G
Sbjct: 11481 KYIISAKNSSGHAQGSAIVNVLDRPG 11506
Score = 49.2 bits (112), Expect = 1e-05
Identities = 35/157 (22%), Positives = 69/157 (43%), Gaps = 7/157 (4%)
Query: 36 ADFESSYDDGTARLKIKQVTAEDEGTYT---CEASNCLGKAKSNACLVVYHTRRLSSPG- 91
+ F SS +K ++A+ + E S+ SN + T ++ G
Sbjct: 26768 SSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMTQLESSTSKMLKAGI 26827
Query: 92 RQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSII--TPSARITVKEKEE 149
R + P P + ++EG+ +T CA G P+P +W G I R ++ ++
Sbjct: 26828 RGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDD 26887
Query: 150 IMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
+ ++ +D V +D G+Y +++ NE G A+ + +
Sbjct: 26888 LTTLIIMD-VQKQDGGLYTLSLGNEFGSDSATVNIHI 26923
Score = 48.4 bits (110), Expect = 2e-05
Identities = 24/86 (27%), Positives = 41/86 (47%), Gaps = 1/86 (1%)
Query: 106 VVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVG 165
+ +E N K +KG P+P SW K + R++V E + L + + D G
Sbjct: 13496 LAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSV-ESSAVNTTLIVYDCQKSDAG 13554
Query: 166 IYRITVENELGRAEASARLEVITRSG 191
Y IT++N G E + ++V+ + G
Sbjct: 13555 KYTITLKNVAGTKEGTISIKVVGKPG 13580
Score = 48.4 bits (110), Expect = 2e-05
Identities = 27/103 (26%), Positives = 46/103 (44%), Gaps = 1/103 (0%)
Query: 106 VVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVG 165
+++ GE + V G P P W KDG + +A++ +K + ++ D D G
Sbjct: 14975 ILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTR-RDSG 15033
Query: 166 IYRITVENELGRAEASARLEVITRSGKFYGGLRAYSASPRKCL 208
Y +T N G A+ ++V+ R G G L + KC+
Sbjct: 15034 AYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCV 15076
Score = 48.4 bits (110), Expect = 2e-05
Identities = 37/165 (22%), Positives = 68/165 (41%), Gaps = 2/165 (1%)
Query: 51 IKQVTAEDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEG 110
I +T + + A N +G SN VV + S G + Y G
Sbjct: 20332 ISGLTQNSQYEFRVFARNAVGSI-SNPSEVVGPITCIDSYGGPVIDLPLEYTEVVKYRAG 20390
Query: 111 ENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRIT 170
+V + + G P+P W KD + +A + V+ ++ IL I + + G Y +
Sbjct: 20391 TSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASIL-IKDADRLNSGCYELK 20449
Query: 171 VENELGRAEASARLEVITRSGKFYGGLRAYSASPRKCLSYRRRPS 215
+ N +G A A+ R++++ + G G + + + K R P+
Sbjct: 20450 LRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEKITLLWRPPA 20494
Score = 48.0 bits (109), Expect = 3e-05
Identities = 25/96 (26%), Positives = 42/96 (43%), Gaps = 4/96 (4%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G++ F C G P P + W +V+ A + + + +I V A DEG Y+
Sbjct: 26077 EGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSV 26136
Query: 65 EASNCLGKAKSNACLVVYHTR----RLSSPGRQMAP 96
N GK ++ L + R ++SP R +P
Sbjct: 26137 VVENSEGKQEAEFTLTIQKARVTEKAVTSPPRVKSP 26172
Score = 47.6 bits (108), Expect = 3e-05
Identities = 30/83 (36%), Positives = 37/83 (44%)
Query: 104 NKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIED 163
N + EG VTF C + G P P +W KDG I R + ++ L I V ED
Sbjct: 1253 NYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPED 1312
Query: 164 VGIYRITVENELGRAEASARLEV 186
GIY N G A S +L V
Sbjct: 1313 EGIYTAFASNIKGNAICSGKLYV 1335
Score = 47.6 bits (108), Expect = 3e-05
Identities = 44/191 (23%), Positives = 78/191 (40%), Gaps = 18/191 (9%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G+T F C+++ + + WF + S + T +L++K+VT +D
Sbjct: 5090 EGETATFVCELS-HEKMHVVWFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLDDISQIKA 5148
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
+ + S A L V + P F +K E + +T KC V +
Sbjct: 5149 QVK----ELSSTAQLKVL----------EADPYFTVKLHDKTAVEKDEITLKCEVSKDVP 5194
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
W KDG I PS + ++K + + RIL+I + ++D G Y + +A +
Sbjct: 5195 --VKWFKDGEEIVPSPKYSIK-ADGLRRILKIKKADLKDKGEYVCDCGTDKTKANVTVEA 5251
Query: 185 EVITRSGKFYG 195
+I YG
Sbjct: 5252 RLIKVEKPLYG 5262
Score = 47.6 bits (108), Expect = 3e-05
Identities = 35/98 (35%), Positives = 41/98 (41%), Gaps = 9/98 (9%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADF------ESSYDDGTARLKIKQVTAEDE 59
G+ V VTG P P I W VI D E S + L I + ED+
Sbjct: 8916 GEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDK 8975
Query: 60 GTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPT 97
GTYT ASN LG N + VY SP R +A T
Sbjct: 8976 GTYTVTASNRLGSVFRNVHVEVYDR---PSPPRNLAVT 9010
Score = 47.6 bits (108), Expect = 3e-05
Identities = 31/108 (28%), Positives = 48/108 (44%), Gaps = 2/108 (1%)
Query: 106 VVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVG 165
VV+ GE + + G P P SW KDG I AR + + +L + + D G
Sbjct: 19303 VVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDN-HTLLTVKDCIRRDTG 19361
Query: 166 IYRITVENELGRAEASARLEVITRSGKFYGGLRAYSASPRKC-LSYRR 212
Y +T++N G + +V+ + G G L + KC LS+ R
Sbjct: 19362 QYVLTLKNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLSWGR 19409
Score = 47.6 bits (108), Expect = 3e-05
Identities = 24/76 (31%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
Query: 106 VVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVG 165
+ + GE+V KG P P +W KD + AR ++ E + +L I +V+ D G
Sbjct: 20785 IAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSI-ENTDSSSLLTIPQVTRNDTG 20843
Query: 166 IYRITVENELGRAEAS 181
Y +T+EN +G ++S
Sbjct: 20844 KYILTIENGVGEPKSS 20859
Score = 47.2 bits (107), Expect = 4e-05
Identities = 27/73 (36%), Positives = 36/73 (49%), Gaps = 3/73 (4%)
Query: 116 KCAVK--GNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVEN 173
K AVK G P P A W KDG IT + + E + LEI + D G+Y TV+N
Sbjct: 26373 KFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGF-FLEIHKTDTSDSGLYTCTVKN 26431
Query: 174 ELGRAEASARLEV 186
G +S +L +
Sbjct: 26432 SAGSVSSSCKLTI 26444
Score = 46.8 bits (106), Expect = 6e-05
Identities = 34/94 (36%), Positives = 46/94 (48%), Gaps = 3/94 (3%)
Query: 95 APTFYTYPFNKVVE-EGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRI 153
APTF T P VV EG TF+ + G P P SW +DG +I+ S V+ R
Sbjct: 5 APTF-TQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRA 63
Query: 154 -LEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
L I V+ + G Y + N G+A ++A L V
Sbjct: 64 KLTIPAVTKANSGRYSLKATNGSGQATSTAELLV 97
Score = 46.8 bits (106), Expect = 6e-05
Identities = 27/85 (31%), Positives = 41/85 (48%), Gaps = 3/85 (3%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
++ G+ + +KG P P +W K+ ARI V + LEI + ED GI
Sbjct: 10733 IKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTP---VGSKLEIRNAAHEDGGI 10789
Query: 167 YRITVENELGRAEASARLEVITRSG 191
Y +TVEN G S ++ V+ + G
Sbjct: 10790 YSLTVENPAGSKTVSVKVLVLDKPG 10814
Score = 46.4 bits (105), Expect = 8e-05
Identities = 26/92 (28%), Positives = 45/92 (48%), Gaps = 1/92 (1%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
V G V + G P P ASW GS + S R+TV+ ++ + L I E +I D G
Sbjct: 23253 VPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAK-LTIRETTIRDTGE 23311
Query: 167 YRITVENELGRAEASARLEVITRSGKFYGGLR 198
Y + ++N G + ++ ++ + G G ++
Sbjct: 23312 YTLELKNVTGTTSETIKVIILDKPGPPTGPIK 23343
Score = 45.6 bits (103), Expect = 1e-04
Identities = 23/93 (24%), Positives = 46/93 (49%), Gaps = 1/93 (1%)
Query: 106 VVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVG 165
+++ GE++ K V+G P P +W KDG I + + + + + + + + G
Sbjct: 21472 IIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLF-VRDATRDHRG 21530
Query: 166 IYRITVENELGRAEASARLEVITRSGKFYGGLR 198
+Y + +N G A+A +++V GK G +R
Sbjct: 21531 VYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIR 21563
Score = 45.6 bits (103), Expect = 1e-04
Identities = 27/95 (28%), Positives = 43/95 (45%), Gaps = 5/95 (5%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+++ + V G P P + WF I + E + G+ L ++ T + G YT E
Sbjct: 21476 GESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVE 21535
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYT 100
A N G AK+ + V T PG+ + P +T
Sbjct: 21536 AKNASGSAKAEIKVKVQDT-----PGKVVGPIRFT 21565
Score = 45.2 bits (102), Expect = 2e-04
Identities = 49/189 (25%), Positives = 75/189 (39%), Gaps = 21/189 (11%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G T EC+V+ + ++WF I +E D +L I T ED TYTC
Sbjct: 5801 EGATAVLECEVS-RENAKVKWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTC 5859
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
+A + K N +V H L R + + V E E F+C + +
Sbjct: 5860 DAKDF--KTSCNLNVVPPHVEFL----RPLT--------DLQVREKEMARFECEL-SREN 5904
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
W KDG+ I + + K + RIL I++ ++D Y E+ A S L
Sbjct: 5905 AKVKWFKDGAEIKKGKKYDIISKGAV-RILVINKCLLDDEAEYSC----EVRTARTSGML 5959
Query: 185 EVITRSGKF 193
V+ F
Sbjct: 5960 TVLEEEAVF 5968
Score = 44.8 bits (101), Expect = 2e-04
Identities = 25/78 (32%), Positives = 38/78 (48%), Gaps = 2/78 (2%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYD--DGTARLKIKQVTAEDEGTY 62
+G +V F CQV GNP P + W + ++ SY+ G +L I A+D G Y
Sbjct: 1049 EGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEY 1108
Query: 63 TCEASNCLGKAKSNACLV 80
T N G+ ++A L+
Sbjct: 1109 TIVVRNKHGETSASASLL 1126
Score = 44.8 bits (101), Expect = 2e-04
Identities = 31/112 (27%), Positives = 46/112 (41%), Gaps = 4/112 (3%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G+T F C+VTG P P + W+ ++IR F Y DG L I + D G
Sbjct: 1808 EGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRY-DGIHYLDIVDCKSYDTGEVKV 1866
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGR---QMAPTFYTYPFNKVVEEGENV 113
A N G + L + S R + P F+ + K+ E + V
Sbjct: 1867 TAENPEGVIEHKVKLEIQQREDFRSVLRRAPEPRPEFHVHEPGKLQFEVQKV 1918
Score = 44.8 bits (101), Expect = 2e-04
Identities = 51/183 (27%), Positives = 70/183 (38%), Gaps = 15/183 (8%)
Query: 6 GDTVEFECQVTGNPDPDIR-WFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
G + FEC V+ P I W IR+ D +L I V D G YTC
Sbjct: 4636 GSSAIFECLVS--PSTAITTWMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSDAGEYTC 4693
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
+ S A LVV P R + T V +G+ + C + N
Sbjct: 4694 VLRLGNKEKTSTAKLVVEEL-----PVRFVK----TLEEEVTVVKGQPLYLSCEL--NKE 4742
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
W KDG I+ V +MR L I++ D G Y +TVEN E S+ +
Sbjct: 4743 RDVVWRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGTYTVTVEN-ANNLECSSCV 4801
Query: 185 EVI 187
+V+
Sbjct: 4802 KVV 4804
Score = 44.8 bits (101), Expect = 2e-04
Identities = 46/163 (28%), Positives = 67/163 (41%), Gaps = 19/163 (11%)
Query: 53 QVTAED-----EGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVV 107
Q T ED E + +A N G +K +A + +R P P+ F +V
Sbjct: 9578 QFTVEDLVEGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMP-----PSIDLKEFMEV- 9631
Query: 108 EEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSI------ 161
EEG NV +KG P P +W K P + V + +++ D ++
Sbjct: 9632 EEGTNVNIVAKIKGVPFPTLTWFK-APPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSR 9690
Query: 162 -EDVGIYRITVENELGRAEASARLEVITRSGKFYGGLRAYSAS 203
D G+Y IT N LG A RL V+ R G G ++ S S
Sbjct: 9691 RSDTGLYTITAVNNLGTASKEMRLNVLGRPGPPVGPIKFESVS 9733
Score = 44.8 bits (101), Expect = 2e-04
Identities = 34/142 (23%), Positives = 58/142 (40%), Gaps = 7/142 (4%)
Query: 51 IKQVTAEDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKV-VEE 109
+K + D Y A N +G+ K + C T+ ++ PT + +K+ +
Sbjct: 10281 VKGLKEGDTYEYRVSAVNIVGQGKPSFC-----TKPITCKDELAPPTLHLDFRDKLTIRV 10335
Query: 110 GENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRI 169
GE G P P SW KD + + R +K + + +I + D G Y +
Sbjct: 10336 GEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKI-KAKRSDSGKYCV 10394
Query: 170 TVENELGRAEASARLEVITRSG 191
VEN G + ++ V+ R G
Sbjct: 10395 VVENSTGSRKGFCQVNVVDRPG 10416
Score = 44.8 bits (101), Expect = 2e-04
Identities = 26/99 (26%), Positives = 43/99 (43%), Gaps = 1/99 (1%)
Query: 93 QMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMR 152
Q+ P P ++ G+ + + V G P P W K + S+ + V K +
Sbjct: 12399 QLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAV-HKADSSS 12457
Query: 153 ILEIDEVSIEDVGIYRITVENELGRAEASARLEVITRSG 191
IL I +V+ +D G Y +T EN G ++ V+ G
Sbjct: 12458 ILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPG 12496
Score = 44.4 bits (100), Expect = 3e-04
Identities = 28/93 (30%), Positives = 41/93 (44%), Gaps = 1/93 (1%)
Query: 95 APTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDG-SIITPSARITVKEKEEIMRI 153
AP F N V N T C V G+P P W + G II + ++E +
Sbjct: 24430 APHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQ 24489
Query: 154 LEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
L I V+ +D +Y++ N+ G +A LEV
Sbjct: 24490 LIIASVTDDDATVYQVRATNQGGSVSGTASLEV 24522
Score = 44.0 bits (99), Expect = 4e-04
Identities = 36/145 (24%), Positives = 59/145 (40%), Gaps = 7/145 (4%)
Query: 48 RLKIKQVTAEDEGTYTCEASNCLGKAKS-NACLVVYHTRRLSSPGRQMAPTFYTYPFNKV 106
R + + A +E + A N GK S + RL++P + F V
Sbjct: 21815 RYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQ---THV 21871
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
V G ++ A +G P+P A W K S ++ A I + L ++ + D G
Sbjct: 21872 VRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRADIHTTDS---FSTLTVENCNRNDAGK 21928
Query: 167 YRITVENELGRAEASARLEVITRSG 191
Y +TVEN G + ++V+ G
Sbjct: 21929 YTLTVENNSGSKSITFTVKVLDTPG 21953
Score = 43.6 bits (98), Expect = 6e-04
Identities = 30/103 (29%), Positives = 46/103 (44%), Gaps = 6/103 (5%)
Query: 92 RQMAPTFYTYPFNK---VVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKE 148
R+MAP F + VV G ++ +KG P+P +W KD + A I E
Sbjct: 14273 REMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANI---ENT 14329
Query: 149 EIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVITRSG 191
E +L I E + D G + +T+EN G+ + V+ G
Sbjct: 14330 ESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPG 14372
Score = 43.6 bits (98), Expect = 6e-04
Identities = 24/69 (34%), Positives = 34/69 (49%), Gaps = 3/69 (4%)
Query: 119 VKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRA 178
+KG P P W+K I+T A+I V +L ID V+ D G Y +T+EN G
Sbjct: 18634 IKGRPEPEVKWEKAEGILTDRAQIEVTSS---FTMLVIDNVTRFDSGRYNLTLENNSGSK 18690
Query: 179 EASARLEVI 187
A + V+
Sbjct: 18691 TAFVNVRVL 18699
Score = 43.2 bits (97), Expect = 7e-04
Identities = 24/85 (28%), Positives = 36/85 (42%), Gaps = 1/85 (1%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
V+ G + V G P P +W K I+ RIT++ + + +D D G
Sbjct: 7205 VKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDS-KRSDTGT 7263
Query: 167 YRITVENELGRAEASARLEVITRSG 191
Y I N GRA A + V+ + G
Sbjct: 7264 YIIEAVNVCGRATAVVEVNVLDKPG 7288
Score = 43.2 bits (97), Expect = 7e-04
Identities = 29/88 (32%), Positives = 41/88 (46%), Gaps = 5/88 (5%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSII---TPSARITVKE--KEEIMRILEIDEVSI 161
V+ GE V V G P P W K+ ++I T + +IT +E + E L I +
Sbjct: 8913 VKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVR 8972
Query: 162 EDVGIYRITVENELGRAEASARLEVITR 189
ED G Y +T N LG + +EV R
Sbjct: 8973 EDKGTYTVTASNRLGSVFRNVHVEVYDR 9000
Score = 43.2 bits (97), Expect = 7e-04
Identities = 26/103 (25%), Positives = 47/103 (45%), Gaps = 4/103 (3%)
Query: 107 VEEGENVTFKCAVKGNPSPWASW--DKDGSIITPSARITVKEKEEIMRILEIDEVSIEDV 164
V+ G+ + + V+G P P +W DKD + +T S R+ + + + + + + D
Sbjct: 11716 VKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSK-FSLTKAKRSDG 11774
Query: 165 GIYRITVENELGRAEASARLEVITRSGKFYGGLRAYSASPRKC 207
G Y +T N G A A + V+ + G L+ S +C
Sbjct: 11775 GKYVVTATNTAGSFVAYATVNVLDKPGP-VRNLKIVDVSSDRC 11816
Score = 43.2 bits (97), Expect = 7e-04
Identities = 26/91 (28%), Positives = 39/91 (42%), Gaps = 5/91 (5%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+ ++ E V G P P+I W E ++ + L IK+ +D G YT
Sbjct: 17829 GEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVT 17888
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAP 96
A+N G A N ++V L PG + P
Sbjct: 17889 ATNSAGTATENLSVIV-----LEKPGPPVGP 17914
Score = 42.7 bits (96), Expect = 0.001
Identities = 27/95 (28%), Positives = 38/95 (40%), Gaps = 5/95 (5%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+ E V+G P P + W + + A E D + L K T D G YT
Sbjct: 14979 GEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLT 15038
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYT 100
A+N G AK +++ + L PG P T
Sbjct: 15039 ATNPGGFAKH-----IFNVKVLDRPGPPEGPLAVT 15068
Score = 42.7 bits (96), Expect = 0.001
Identities = 19/56 (33%), Positives = 31/56 (55%), Gaps = 1/56 (1%)
Query: 22 DIRWFHYAEVIRDCADFESSYD-DGTARLKIKQVTAEDEGTYTCEASNCLGKAKSN 76
++ W+ + +++ F+ Y DGT LKI +T D+G Y CE S G +K+N
Sbjct: 26251 EVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTN 26306
Score = 42.3 bits (95), Expect = 0.001
Identities = 23/76 (30%), Positives = 34/76 (44%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G T+ +V G P+PDI W +V+ + D L+IK+ D G Y
Sbjct: 11426 GQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKYIIS 11485
Query: 66 ASNCLGKAKSNACLVV 81
A N G A+ +A + V
Sbjct: 11486 AKNSSGHAQGSAIVNV 11501
Score = 42.3 bits (95), Expect = 0.001
Identities = 24/85 (28%), Positives = 39/85 (45%), Gaps = 3/85 (3%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
+ G ++ +V G P P +W K G + A I E + L +D+V+ D G
Sbjct: 22961 IRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSL---LIVDKVNRYDAGK 23017
Query: 167 YRITVENELGRAEASARLEVITRSG 191
Y I EN+ G+ A+ ++V G
Sbjct: 23018 YTIEAENQSGKKSATVLVKVYDTPG 23042
Score = 42.3 bits (95), Expect = 0.001
Identities = 24/81 (29%), Positives = 36/81 (44%), Gaps = 3/81 (3%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
V +G + +KG P P W K+G I+ A I E + I E D D G
Sbjct: 23651 VRQGGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETHTELVIKEADR---GDSGT 23707
Query: 167 YRITVENELGRAEASARLEVI 187
Y + +EN+ G+ ++ VI
Sbjct: 23708 YDLVLENKCGKKAVYIKVRVI 23728
Score = 42.3 bits (95), Expect = 0.001
Identities = 21/72 (29%), Positives = 30/72 (41%)
Query: 10 EFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNC 69
+F + TG P P W + I ++ S D G L+I + D G YTC N
Sbjct: 26373 KFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNS 26432
Query: 70 LGKAKSNACLVV 81
G S+ L +
Sbjct: 26433 AGSVSSSCKLTI 26444
Score = 41.9 bits (94), Expect = 0.002
Identities = 38/138 (27%), Positives = 59/138 (42%), Gaps = 10/138 (7%)
Query: 54 VTAEDEGTYTCEASNCLGKAKSNACLV----VYHTRRLSSPGRQMAPTFYTYPFNKVVEE 109
++AE+EG ++ E L K L+ VY T+ S P F N +
Sbjct: 3414 LSAEEEGLHSAELQ--LSKINETLELLSESPVYSTK-FDSEKEGTGPIFIKEVSNADISM 3470
Query: 110 GENVTFKCAVKGNPSPWASWDKDGSIITPSARIT-VKEKEEIMRILEIDEVSIEDVGIYR 168
G+ T V G P P W +G ++TPSA V + ++ I+ +ED G Y
Sbjct: 3471 GDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILF--TKLEDEGEYT 3528
Query: 169 ITVENELGRAEASARLEV 186
N+ G+ SA L++
Sbjct: 3529 CMASNDYGKTICSAYLKI 3546
Score = 41.9 bits (94), Expect = 0.002
Identities = 30/126 (23%), Positives = 50/126 (39%), Gaps = 4/126 (3%)
Query: 51 IKQVTAEDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEG 110
++ +T +E T+ A N G++ V + P + + K G
Sbjct: 14527 VRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVIAKA---G 14583
Query: 111 ENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRIT 170
+N+ + V G P P +W K I+ + R+ E IL I+E D G Y +T
Sbjct: 14584 DNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNF-ETTATSTILNINECVRSDSGPYPLT 14642
Query: 171 VENELG 176
N +G
Sbjct: 14643 ARNIVG 14648
Score = 41.5 bits (93), Expect = 0.002
Identities = 27/97 (27%), Positives = 43/97 (44%), Gaps = 2/97 (2%)
Query: 96 PTFYTYPFNK-VVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRIL 154
P + FN V GE++ G P+P +W KD + + R+ E E +L
Sbjct: 15650 PPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNA-ESTENNSLL 15708
Query: 155 EIDEVSIEDVGIYRITVENELGRAEASARLEVITRSG 191
I + EDVG Y + + N G A + + V+ + G
Sbjct: 15709 TIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPG 15745
Score = 41.1 bits (92), Expect = 0.003
Identities = 25/102 (24%), Positives = 43/102 (42%), Gaps = 1/102 (0%)
Query: 106 VVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVG 165
VV GE+ + G P P W K ++ +AR+ +K + + D V + D G
Sbjct: 16057 VVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRV-DSG 16115
Query: 166 IYRITVENELGRAEASARLEVITRSGKFYGGLRAYSASPRKC 207
Y + +N G + ++V+ R G G + + KC
Sbjct: 16116 NYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISGVTAEKC 16157
Score = 41.1 bits (92), Expect = 0.003
Identities = 27/102 (26%), Positives = 41/102 (40%), Gaps = 1/102 (0%)
Query: 106 VVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVG 165
VV GE + V G P P W + I SAR +K + ++ D + I D G
Sbjct: 17139 VVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRI-DGG 17197
Query: 166 IYRITVENELGRAEASARLEVITRSGKFYGGLRAYSASPRKC 207
Y + N G ++V+ R G G ++ + KC
Sbjct: 17198 QYILRASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKC 17239
Score = 41.1 bits (92), Expect = 0.003
Identities = 27/103 (26%), Positives = 44/103 (42%), Gaps = 2/103 (1%)
Query: 106 VVEEGENVTFKCAVKGNPSPWASWDKDG-SIITPSARITVKEKEEIMRILEIDEVSIEDV 164
VV GE + ++G P P W KDG + +AR+ +K + L + + D
Sbjct: 18221 VVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQ-KTTLVVKDCIRTDG 18279
Query: 165 GIYRITVENELGRAEASARLEVITRSGKFYGGLRAYSASPRKC 207
G Y + + N G ++V+ R G G L+ + KC
Sbjct: 18280 GQYILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKC 18322
Score = 41.1 bits (92), Expect = 0.003
Identities = 24/91 (26%), Positives = 33/91 (36%), Gaps = 5/91 (5%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G VE + G P P WF +R+ A+L I++ T D G YT E
Sbjct: 23256 GRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLE 23315
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAP 96
N G +++ L PG P
Sbjct: 23316 LKNVTGTTSETIKVII-----LDKPGPPTGP 23341
Score = 40.7 bits (91), Expect = 0.004
Identities = 28/95 (29%), Positives = 37/95 (38%)
Query: 92 RQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIM 151
R P F P + EG+ F V G P P W DG I V KE+
Sbjct: 1407 RLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGT 1466
Query: 152 RILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
+ L I + D G + + +N GR+ S L V
Sbjct: 1467 QSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTV 1501
Score = 40.3 bits (90), Expect = 0.005
Identities = 19/76 (25%), Positives = 32/76 (42%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G F V P +++W+H +++ + + G L+I +D GTY
Sbjct: 25891 GQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAV 25950
Query: 66 ASNCLGKAKSNACLVV 81
+N G+A A L V
Sbjct: 25951 CTNYKGEASDYATLDV 25966
Score = 39.9 bits (89), Expect = 0.007
Identities = 43/177 (24%), Positives = 83/177 (46%), Gaps = 22/177 (12%)
Query: 11 FECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCL 70
FEC +T + ++ W ++I+ F+ D L I +DEG YT E
Sbjct: 5008 FECVLTR--EANVIWSKGPDIIKSSDKFDIIADGKKHILVINDSQFDDEGVYTAEVE--- 5062
Query: 71 GKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWD 130
GK K++A L V R + M+P ++ V+EGE TF C + + W
Sbjct: 5063 GK-KTSARLFVTGIRL-----KFMSPL-----EDQTVKEGETATFVCEL-SHEKMHVVWF 5110
Query: 131 KDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVI 187
K+ + + S + + + + + LE+ EV+++D+ ++ ++ ++A+L+V+
Sbjct: 5111 KNDAKLHTSRTVLISSEGKTHK-LEMKEVTLDDIS----QIKAQVKELSSTAQLKVL 5162
Score = 39.9 bits (89), Expect = 0.007
Identities = 24/99 (24%), Positives = 42/99 (42%), Gaps = 1/99 (1%)
Query: 110 GENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRI 169
G T + G P+P +W + + + R+++ ++ L + + D G Y +
Sbjct: 22165 GSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKD-RTTLTVKDSMRGDSGRYFL 22223
Query: 170 TVENELGRAEASARLEVITRSGKFYGGLRAYSASPRKCL 208
T+EN G S + VI R G G + S S C+
Sbjct: 22224 TLENTAGVKTFSVTVVVIGRPGPVTGPIEVSSVSAESCV 22262
Score = 39.5 bits (88), Expect = 0.009
Identities = 23/66 (34%), Positives = 27/66 (40%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+T E V G P P I W + I + A E D A L +K D G Y
Sbjct: 17143 GETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILR 17202
Query: 66 ASNCLG 71
ASN G
Sbjct: 17203 ASNVAG 17208
Score = 38.3 bits (85), Expect = 0.021
Identities = 22/80 (27%), Positives = 35/80 (43%), Gaps = 1/80 (1%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
V+ G+ F + G P P SW K+ +++ + + +L I E ED +
Sbjct: 3204 VQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLI-EAFPEDAAV 3262
Query: 167 YRITVENELGRAEASARLEV 186
Y +N+ G A SA L V
Sbjct: 3263 YTCEAKNDYGVATTSASLSV 3282
Score = 38.3 bits (85), Expect = 0.021
Identities = 29/97 (29%), Positives = 44/97 (45%), Gaps = 4/97 (4%)
Query: 95 APTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRIL 154
AP T + VV+ G+ +T P A W K+ ++ T E+ RIL
Sbjct: 6502 APKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKTIDTTAEQTSF-RIL 6560
Query: 155 EIDEVSIEDVGIYRITVENELGRAEASARLEVITRSG 191
E + D G Y+I ++N+ G+AE L+VI G
Sbjct: 6561 EAKK---GDKGRYKIVLQNKHGKAEGFINLKVIDVPG 6594
Score = 38.3 bits (85), Expect = 0.021
Identities = 24/93 (25%), Positives = 40/93 (43%), Gaps = 7/93 (7%)
Query: 106 VVEEGENVTFKCAVKGNPSPWASWDKDGSI-------ITPSARITVKEKEEIMRILEIDE 158
V + G + +KG P+P +SW+ DG + E E ++ I E
Sbjct: 9324 VCKAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPE 9383
Query: 159 VSIEDVGIYRITVENELGRAEASARLEVITRSG 191
G Y IT +N+ G+ A+ R++V+ G
Sbjct: 9384 CKRSHTGKYSITAKNKAGQKTANCRVKVMDVPG 9416
Score = 38.3 bits (85), Expect = 0.021
Identities = 29/101 (28%), Positives = 42/101 (41%), Gaps = 5/101 (4%)
Query: 95 APTFYTYPFNK---VVEEGENVTFKC-AVKGNPSPWASWDKDGSIITPSARITVKEKEEI 150
APT P K ++ G+ + ++ G P P +SW K G I PS IT
Sbjct: 13878 APTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPS-DITQITSTPT 13936
Query: 151 MRILEIDEVSIEDVGIYRITVENELGRAEASARLEVITRSG 191
+L I + +D G Y IT N G ++ V+ G
Sbjct: 13937 SSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDVPG 13977
Score = 38.3 bits (85), Expect = 0.021
Identities = 22/91 (24%), Positives = 36/91 (39%), Gaps = 5/91 (5%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G++ + + + G P P I+W + + + A E D L +K D G Y +
Sbjct: 16061 GESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILK 16120
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAP 96
A N G+ V + + L PG P
Sbjct: 16121 AKNVAGERS-----VTVNVKVLDRPGPPEGP 16146
Score = 38.3 bits (85), Expect = 0.021
Identities = 25/92 (27%), Positives = 39/92 (42%), Gaps = 2/92 (2%)
Query: 101 YPFNKV-VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEV 159
+P + V V G N+ + G P P + +DG + + R + E + I + E
Sbjct: 19984 FPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTI-NLKES 20042
Query: 160 SIEDVGIYRITVENELGRAEASARLEVITRSG 191
D G Y IT N G +A + V+ R G
Sbjct: 20043 VTADAGRYEITAANSSGTTKAFINIVVLDRPG 20074
Score = 37.9 bits (84), Expect = 0.027
Identities = 29/98 (29%), Positives = 43/98 (43%), Gaps = 1/98 (1%)
Query: 89 SPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKE 148
SP + AP + ++ V +G + F+ V G P P W K+G I S RI E
Sbjct: 2026 SPSME-APKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPE 2084
Query: 149 EIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
+ + L I +V+ ED + N G + A L V
Sbjct: 2085 DNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLV 2122
Score = 37.5 bits (83), Expect = 0.036
Identities = 21/86 (24%), Positives = 38/86 (44%), Gaps = 1/86 (1%)
Query: 106 VVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVG 165
++ G + VKG P P +W K + + +K + L + V+ D G
Sbjct: 13207 ILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTD-FDTFLRCENVNKYDAG 13265
Query: 166 IYRITVENELGRAEASARLEVITRSG 191
Y +T+EN G+ E + ++V+ G
Sbjct: 13266 KYILTLENSCGKKEYTIVVKVLDTPG 13291
Score = 37.1 bits (82), Expect = 0.048
Identities = 24/86 (27%), Positives = 35/86 (40%), Gaps = 3/86 (3%)
Query: 106 VVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVG 165
VV G + KG P+P +W ++ T +I EK L ID D G
Sbjct: 17538 VVRAGGSARIHIPFKGRPTPEITWSREEGEFTDKVQI---EKGVNYTQLSIDNCDRNDAG 17594
Query: 166 IYRITVENELGRAEASARLEVITRSG 191
Y + +EN G A ++V+ G
Sbjct: 17595 KYILKLENSSGSKSAFVTVKVLDTPG 17620
Score = 37.1 bits (82), Expect = 0.048
Identities = 21/75 (28%), Positives = 32/75 (42%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+ V+ G P P + W + + A + D ++ L I QVT D G Y
Sbjct: 20789 GEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILT 20848
Query: 66 ASNCLGKAKSNACLV 80
N +G+ KS+ V
Sbjct: 20849 IENGVGEPKSSTVSV 20863
Score = 36.7 bits (81), Expect = 0.063
Identities = 40/162 (24%), Positives = 69/162 (42%), Gaps = 17/162 (10%)
Query: 10 EFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNC 69
E EC V+ + + +W+H ++ + + G L +K VT ED+G Y+
Sbjct: 2239 ELECIVSPE-NIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVID-- 2295
Query: 70 LGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASW 129
K C +L R +A ++ V EG+ V + V S W
Sbjct: 2296 ---GKKTTC-------KLKMKPRPIA--ILQGLSDQKVCEGDIVQLEVKV-SLESVEGVW 2342
Query: 130 DKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITV 171
KDG + PS R+ + ++ +L I++++ ED G Y T+
Sbjct: 2343 MKDGQEVQPSDRVHIVIDKQ-SHMLLIEDMTKEDAGNYSFTI 2383
Score = 36.7 bits (81), Expect = 0.063
Identities = 26/96 (27%), Positives = 38/96 (39%), Gaps = 1/96 (1%)
Query: 110 GENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRI 169
G+N F V+ P+ W +G + S++I ++ LEI + +D G YR
Sbjct: 25891 GQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLT-LEILDCHTDDSGTYRA 25949
Query: 170 TVENELGRAEASARLEVITRSGKFYGGLRAYSASPR 205
N G A A L+V Y R PR
Sbjct: 25950 VCTNYKGEASDYATLDVTGGDYTTYASQRRDEEVPR 25985
Score = 36.3 bits (80), Expect = 0.084
Identities = 21/79 (26%), Positives = 34/79 (43%), Gaps = 2/79 (2%)
Query: 11 FECQVT--GNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
FEC++T G+P + W H + + + G L + D G TC A+N
Sbjct: 1676 FECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATN 1735
Query: 69 CLGKAKSNACLVVYHTRRL 87
G ++A L+V + L
Sbjct: 1736 KYGTDHTSATLIVKDEKSL 1754
Score = 36.3 bits (80), Expect = 0.084
Identities = 23/81 (28%), Positives = 35/81 (43%), Gaps = 3/81 (3%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
+ G ++ +KG P+P W K I +A I V L +D V+ D G
Sbjct: 16457 IRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSS---FTSLVLDNVNRYDSGK 16513
Query: 167 YRITVENELGRAEASARLEVI 187
Y +T+EN G A + V+
Sbjct: 16514 YTLTLENSSGTKSAFVTVRVL 16534
Score = 35.9 bits (79), Expect = 0.11
Identities = 45/178 (25%), Positives = 69/178 (38%), Gaps = 22/178 (12%)
Query: 11 FECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCL 70
FEC+V NPD W + + + S D RL I +D G YT + +
Sbjct: 2593 FECEVA-NPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTYKVAT-- 2649
Query: 71 GKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWD 130
+K++A +L ++ T N V E ++ F + W
Sbjct: 2650 --SKTSA--------KLKVEAVKIKKTLK----NLTVTETQDAVFTVELTHPNVKGVQWI 2695
Query: 131 KDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVIT 188
K+G ++ + + + K I L I +I D +Y LGR ASARL V T
Sbjct: 2696 KNGVVLESNEKYAISVKGTIYS-LRIKNCAIVDESVYGF----RLGRLGASARLHVET 2748
Score = 35.5 bits (78), Expect = 0.15
Identities = 21/76 (27%), Positives = 31/76 (40%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G + E V G P P +W + + + D ++ L IK VT +D G Y+
Sbjct: 12416 GKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLT 12475
Query: 66 ASNCLGKAKSNACLVV 81
A N G +VV
Sbjct: 12476 AENSSGTDTQKIKVVV 12491
Score = 35.1 bits (77), Expect = 0.19
Identities = 22/73 (30%), Positives = 31/73 (42%), Gaps = 3/73 (4%)
Query: 119 VKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRA 178
+KG P+P W +D A I E +L + V+ D G Y +TVEN G
Sbjct: 15387 IKGRPAPEVKWARDHGESLDKASI---ESTSSYTLLIVGNVNRFDSGKYILTVENSSGSK 15443
Query: 179 EASARLEVITRSG 191
A + V+ G
Sbjct: 15444 SAFVNVRVLDTPG 15456
Score = 35.1 bits (77), Expect = 0.19
Identities = 22/79 (27%), Positives = 35/79 (44%), Gaps = 2/79 (2%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G ++ V+G P P I W + A +++ + + L + +V D G YT E
Sbjct: 22964 GASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTT--ESYSLLIVDKVNRYDAGKYTIE 23021
Query: 66 ASNCLGKAKSNACLVVYHT 84
A N GK + + VY T
Sbjct: 23022 AENQSGKKSATVLVKVYDT 23040
Score = 35.1 bits (77), Expect = 0.19
Identities = 23/82 (28%), Positives = 36/82 (43%), Gaps = 1/82 (1%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDD-GTARLKIKQVTAEDEGTYT 63
+G +V FE +V+G P P ++W + + + E ++ L I+ ED G Y
Sbjct: 25311 EGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYR 25370
Query: 64 CEASNCLGKAKSNACLVVYHTR 85
A+N G A L V R
Sbjct: 25371 VTATNTAGSTSCQAHLQVERLR 25392
Score = 34.7 bits (76), Expect = 0.26
Identities = 19/68 (27%), Positives = 27/68 (39%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G +E VTG P+P I W +++ + + I D GTY E
Sbjct: 7208 GTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIE 7267
Query: 66 ASNCLGKA 73
A N G+A
Sbjct: 7268 AVNVCGRA 7275
Score = 34.7 bits (76), Expect = 0.26
Identities = 25/91 (27%), Positives = 32/91 (35%), Gaps = 5/91 (5%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G TV F + G P P +W I+ + D+ ++ L IK D G Y
Sbjct: 11028 GTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQIT 11087
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAP 96
SN G V H L PG P
Sbjct: 11088 VSNAAGSK-----TVAVHLTVLDVPGPPTGP 11113
Score = 34.7 bits (76), Expect = 0.26
Identities = 22/71 (30%), Positives = 31/71 (43%), Gaps = 1/71 (1%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
V G NV + KG P P SW KDG + S + + E + L I E G
Sbjct: 21078 VRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKI-TLSIKNAKKEHGGK 21136
Query: 167 YRITVENELGR 177
Y + ++N + R
Sbjct: 21137 YTVILDNAVCR 21147
Score = 34.3 bits (75), Expect = 0.34
Identities = 38/174 (21%), Positives = 69/174 (39%), Gaps = 19/174 (10%)
Query: 7 DTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEA 66
D F CQ++ +++W+ I++ ++ D RL IK +DE Y C
Sbjct: 6341 DDAVFSCQLS-REKANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKDCRLDDECEYACGV 6399
Query: 67 SNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVE-EGENVTFKCAVKGNPSP 125
+ KS A L V + P P ++E G +V F A
Sbjct: 6400 ED----RKSRARLFV-----------EEIPVEIIRPPQDILEAPGADVVF-LAELNKDKV 6443
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAE 179
W ++ ++ + + + +I R L+I ++ D G YR +++ RA+
Sbjct: 6444 EVQWLRNNMVVVQGDKHQMMSEGKIHR-LQICDIKPRDQGEYRFIAKDKEARAK 6496
Score = 34.3 bits (75), Expect = 0.34
Identities = 16/67 (23%), Positives = 27/67 (40%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
GD ++ E V G P P + W ++++ + L I + D G Y
Sbjct: 14583 GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLT 14642
Query: 66 ASNCLGK 72
A N +G+
Sbjct: 14643 ARNIVGE 14649
Score = 34.3 bits (75), Expect = 0.34
Identities = 20/86 (23%), Positives = 37/86 (43%), Gaps = 3/86 (3%)
Query: 106 VVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVG 165
+V+ G + T +G P P W K + + A + + L I+ + D G
Sbjct: 19700 IVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRAYVDTTDSR---TSLTIENANRNDSG 19756
Query: 166 IYRITVENELGRAEASARLEVITRSG 191
Y +T++N L A + ++V+ G
Sbjct: 19757 KYTLTIQNVLSAASLTLVVKVLDTPG 19782
Score = 33.5 bits (73), Expect = 0.59
Identities = 36/161 (22%), Positives = 61/161 (37%), Gaps = 17/161 (10%)
Query: 7 DTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEA 66
+ FEC+++ + ++WF I+ ++ L I + +DE Y+CE
Sbjct: 5892 EMARFECELS-RENAKVKWFKDGAEIKKGKKYDIISKGAVRILVINKCLLDDEAEYSCEV 5950
Query: 67 SNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPW 126
A+++ L V + + + +A N V E + + C V P
Sbjct: 5951 RT----ARTSGMLTVLEEEAVFT--KNLA--------NIEVSETDTIKLVCEV-SKPGAE 5995
Query: 127 ASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIY 167
W K I + R + E RIL I +ED G Y
Sbjct: 5996 VIWYKGDEEIIETGRYEIL-TEGRKRILVIQNAHLEDAGNY 6035
Score = 33.1 bits (72), Expect = 0.78
Identities = 20/62 (32%), Positives = 26/62 (41%), Gaps = 1/62 (1%)
Query: 7 DTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEA 66
D +FEC+V+ P RW + I FE D + IK EDE Y EA
Sbjct: 5358 DEAKFECEVSREPKT-FRWLKGTQEITGDDRFELIKDGTKHSMVIKSAAFEDEAKYMFEA 5416
Query: 67 SN 68
+
Sbjct: 5417 ED 5418
Score = 33.1 bits (72), Expect = 0.78
Identities = 23/85 (27%), Positives = 33/85 (38%), Gaps = 5/85 (5%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVI--RDCADFESSYDDGTARLKIKQVTAEDEGTY 62
+G + C TG P P++ W I ++ F D L I V +D G Y
Sbjct: 26845 EGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLY 26904
Query: 63 TCEASNCLGKAKSNACLVVYHTRRL 87
T N G S++ V H R +
Sbjct: 26905 TLSLGNEFG---SDSATVNIHIRSI 26926
Score = 32.7 bits (71), Expect = 1.0
Identities = 18/76 (23%), Positives = 29/76 (38%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G V + V G P P + W +++ + + L++ V +D G YT
Sbjct: 12813 GTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTIT 12872
Query: 66 ASNCLGKAKSNACLVV 81
A N G + L V
Sbjct: 12873 AENSSGSKSATIKLKV 12888
Score = 32.7 bits (71), Expect = 1.0
Identities = 20/67 (29%), Positives = 29/67 (43%), Gaps = 1/67 (1%)
Query: 6 GDTVEFEC-QVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
GDT+ + G P P W + IR + + ++ L IK T +D G YT
Sbjct: 13896 GDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTI 13955
Query: 65 EASNCLG 71
A+N G
Sbjct: 13956 TATNPFG 13962
Score = 32.7 bits (71), Expect = 1.0
Identities = 20/91 (21%), Positives = 35/91 (38%), Gaps = 5/91 (5%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+ ++ + G P P + W ++ + + + L IK ED G Y +
Sbjct: 15665 GEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVK 15724
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAP 96
+N G+A ++V L PG P
Sbjct: 15725 LTNSAGEAIETLNVIV-----LDKPGPPTGP 15750
Score = 32.3 bits (70), Expect = 1.4
Identities = 16/75 (21%), Positives = 29/75 (38%)
Query: 7 DTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEA 66
+ ++ + G P + W + +++ S L IK+ + ED GTY
Sbjct: 18913 EQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCV 18972
Query: 67 SNCLGKAKSNACLVV 81
SN G ++V
Sbjct: 18973 SNSAGSITVPITIIV 18987
Score = 31.9 bits (69), Expect = 1.8
Identities = 22/86 (25%), Positives = 35/86 (40%), Gaps = 2/86 (2%)
Query: 106 VVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVG 165
+V G + V+G P+P +W K G I R + + M L I + +D G
Sbjct: 12120 IVRAGCPIRLFAIVRGRPAPKVTWRKVG--IDNVVRKGQVDLVDTMAFLVIPNSTRDDSG 12177
Query: 166 IYRITVENELGRAEASARLEVITRSG 191
Y +T+ N G + V+ G
Sbjct: 12178 KYSLTLVNPAGEKAVFVNVRVLDTPG 12203
Score = 31.9 bits (69), Expect = 1.8
Identities = 23/102 (22%), Positives = 43/102 (42%), Gaps = 4/102 (3%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVK-EKEEIMRILEIDEVSIEDVG 165
+ G ++ AV G P P W K + +++++ + +++ + S D G
Sbjct: 22562 IRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRS--DSG 22619
Query: 166 IYRITVENELGRAEASARLEVITRSGKFYGGLRAYSASPRKC 207
Y +TV+N G S ++V+ G G L + KC
Sbjct: 22620 KYTLTVKNASGTKAVSVMVKVLDSPGP-CGKLTVSRVTQEKC 22660
Score = 31.5 bits (68), Expect = 2.4
Identities = 10/32 (31%), Positives = 19/32 (59%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITP 138
V+ G+ + ++ G+P P +W KD ++I P
Sbjct: 8194 VKRGDEIALDASISGSPYPTITWIKDENVIVP 8225
Score = 31.5 bits (68), Expect = 2.4
Identities = 21/79 (26%), Positives = 28/79 (35%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G T+ V G P P I W +RD + D L+ + V D G Y
Sbjct: 13211 GVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILT 13270
Query: 66 ASNCLGKAKSNACLVVYHT 84
N GK + + V T
Sbjct: 13271 LENSCGKKEYTIVVKVLDT 13289
Score = 31.5 bits (68), Expect = 2.4
Identities = 24/86 (27%), Positives = 33/86 (38%), Gaps = 5/86 (5%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G + + V G P+P I W + + C Y A IK D G YT
Sbjct: 22565 GSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLT 22624
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPG 91
N G K+ + +V + L SPG
Sbjct: 22625 VKNASG-TKAVSVMV----KVLDSPG 22645
Score = 31.1 bits (67), Expect = 3.2
Identities = 22/102 (21%), Positives = 39/102 (38%), Gaps = 3/102 (2%)
Query: 106 VVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVG 165
VV G + V G P P +W+ + + A I E I + I G
Sbjct: 10038 VVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATI---ETTAISSSMVIKNCQRSHQG 10094
Query: 166 IYRITVENELGRAEASARLEVITRSGKFYGGLRAYSASPRKC 207
+Y + +NE G + + ++V+ G A++ + C
Sbjct: 10095 VYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESC 10136
Score = 31.1 bits (67), Expect = 3.2
Identities = 42/179 (23%), Positives = 63/179 (35%), Gaps = 20/179 (11%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+ ++ + G P P I W I + A E D L +K D G Y
Sbjct: 19307 GEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLT 19366
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVK-GNPS 124
N G V + + L PG P N + E KC++ G P
Sbjct: 19367 LKNVAGTRS-----VAVNCKVLDKPGPPAGP----LEINGLTAE------KCSLSWGRPQ 19411
Query: 125 PWASWDKDGSII----TPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAE 179
D D I+ T T+ E E M ++ ++ + I+R+T N+ G E
Sbjct: 19412 EDGGADIDYYIVEKRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGE 19470
Score = 30.7 bits (66), Expect = 4.2
Identities = 15/59 (25%), Positives = 27/59 (45%), Gaps = 1/59 (1%)
Query: 7 DTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
D V +C+++ D ++WF + I+ + D L +K+ D G YTC+
Sbjct: 5536 DEVILQCEIS-KADAPVKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTCD 5593
Score = 30.7 bits (66), Expect = 4.2
Identities = 20/68 (29%), Positives = 28/68 (41%), Gaps = 6/68 (8%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCA--DFESSYDDGTARLKIKQVTAEDEGTYT 63
G ++ + G P P+++W IRD A D SS+ L + V D G YT
Sbjct: 16460 GGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSF----TSLVLDNVNRYDSGKYT 16515
Query: 64 CEASNCLG 71
N G
Sbjct: 16516 LTLENSSG 16523
Score = 30.7 bits (66), Expect = 4.2
Identities = 16/75 (21%), Positives = 31/75 (41%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G ++ E ++G P P I W ++ + L IK+ +D G Y
Sbjct: 16747 GQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGIT 16806
Query: 66 ASNCLGKAKSNACLV 80
+N +G+ ++ +V
Sbjct: 16807 VANVVGQKTASIEIV 16821
Score = 30.3 bits (65), Expect = 5.5
Identities = 22/84 (26%), Positives = 37/84 (44%), Gaps = 6/84 (7%)
Query: 109 EGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYR 168
E + V +C + +P W KDG I PS +K + R+L + + D+G Y
Sbjct: 5534 EKDEVILQCEISKADAP-VKWFKDGKEIKPSKNAVIKADGK-KRMLILKKALKSDIGQYT 5591
Query: 169 ITVENELGRAEASARLEVITRSGK 192
+ G + S +L++ R K
Sbjct: 5592 C----DCGTDKTSGKLDIEDREIK 5611
Score = 30.3 bits (65), Expect = 5.5
Identities = 20/71 (28%), Positives = 29/71 (40%), Gaps = 2/71 (2%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRD-CADFESSYDDGTARLKIKQVTAEDEGTYTC 64
G+T E + G P PD+ W + + + A E L +K D G Y
Sbjct: 18225 GETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYIL 18284
Query: 65 EASNCLGKAKS 75
+ SN +G KS
Sbjct: 18285 KLSN-VGGTKS 18294
Score = 30.3 bits (65), Expect = 5.5
Identities = 17/64 (26%), Positives = 26/64 (40%), Gaps = 2/64 (3%)
Query: 8 TVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEAS 67
T+ + G P+P+++W ++ D A E + L I VT D G Y
Sbjct: 18627 TLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVT--SSFTMLVIDNVTRFDSGRYNLTLE 18684
Query: 68 NCLG 71
N G
Sbjct: 18685 NNSG 18688
Score = 29.9 bits (64), Expect = 7.3
Identities = 28/99 (28%), Positives = 38/99 (38%), Gaps = 12/99 (12%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCAD---FESSYD----DGTARLKIKQVTAE 57
+G V ++ G P P + WF D + +++ + D T L I Q
Sbjct: 9633 EGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRS 9692
Query: 58 DEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAP 96
D G YT A N LG A L V L PG + P
Sbjct: 9693 DTGLYTITAVNNLGTASKEMRLNV-----LGRPGPPVGP 9726
Score = 29.9 bits (64), Expect = 7.3
Identities = 17/65 (26%), Positives = 22/65 (33%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G V E G P P I W +++ S + L IK E G YT
Sbjct: 21081 GHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVI 21140
Query: 66 ASNCL 70
N +
Sbjct: 21141 LDNAV 21145
Score = 29.5 bits (63), Expect = 9.6
Identities = 18/77 (23%), Positives = 30/77 (38%), Gaps = 1/77 (1%)
Query: 113 VTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVE 172
+T G P P A+W ++ R+ +K ++ I D GIY + +E
Sbjct: 6915 ITILVPSTGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELV-ISPSERSDKGIYTLKLE 6973
Query: 173 NELGRAEASARLEVITR 189
N + + VI R
Sbjct: 6974 NRVKTISGEIDVNVIAR 6990
Score = 29.5 bits (63), Expect = 9.6
Identities = 16/70 (22%), Positives = 29/70 (41%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G +V+ ++G P P I W+ + ++ A A + IK + G Y +
Sbjct: 20390 GTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELK 20449
Query: 66 ASNCLGKAKS 75
N +G A +
Sbjct: 20450 LRNAMGSASA 20459
>AC023270-1|AAX88844.1| 5604|Homo sapiens unknown protein.
Length = 5604
Score = 87.4 bits (207), Expect = 3e-17
Identities = 57/184 (30%), Positives = 92/184 (50%), Gaps = 11/184 (5%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCA--DFESSYDDGTARLKIKQVTAEDEGTY 62
+G T FE ++G P P++ WF +VI + S+ DG A+L I VT + G Y
Sbjct: 19 EGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKANSGRY 78
Query: 63 TCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGN 122
+ +A+N G+A S A L+V + ++P P F + V +G V + V G
Sbjct: 79 SLKATNGSGQATSTAELLV---KAETAP-----PNFVQRLQSMTVRQGSQVRLQVRVTGI 130
Query: 123 PSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASA 182
P+P + +DG+ I S + ++ ++ +L I E ED G Y + N +GRA ++A
Sbjct: 131 PTPVVKFYRDGAEIQSSLDFQISQEGDLYSLL-IAEAYPEDSGTYSVNATNSVGRATSTA 189
Query: 183 RLEV 186
L V
Sbjct: 190 ELLV 193
Score = 77.0 bits (181), Expect = 5e-14
Identities = 52/184 (28%), Positives = 79/184 (42%), Gaps = 8/184 (4%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAE-VIRDCADFESSYDDGTARLKIKQVTAEDEGTYT 63
+G T F+ +V G P P+ WFH + ++ D +DGT L I T D G +T
Sbjct: 1470 EGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWT 1529
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
A N G++ + L V + Q+ P F N ++EG + K GNP
Sbjct: 1530 VVAQNRAGRSSISVILTV------EAVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNP 1583
Query: 124 SPWASWDKDGSIITPSARITVK-EKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASA 182
+P W K+ II P ++ E + L+ID +D Y T N+ GR
Sbjct: 1584 NPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRC 1643
Query: 183 RLEV 186
++ V
Sbjct: 1644 KVNV 1647
Score = 73.3 bits (172), Expect = 6e-13
Identities = 52/184 (28%), Positives = 79/184 (42%), Gaps = 6/184 (3%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G F ++G P P I W+ +++ + +D L + + ED YTCE
Sbjct: 3253 GKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCE 3312
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQM---APTFYTYPFNKVVEEGENVTFKCAVKGN 122
A N G A ++A L V + SP ++M P T + V EG+ F+C V G
Sbjct: 3313 AKNDYGVATTSASLSV-EVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGT 3371
Query: 123 PSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASA 182
SW I PS + + E+ + LEI E ED G Y N +G+ ++A
Sbjct: 3372 DLK-VSWYSKDKKIKPSRFFRMTQFEDTYQ-LEIAEAYPEDEGTYTFVASNAVGQVSSTA 3429
Query: 183 RLEV 186
L +
Sbjct: 3430 NLSL 3433
Score = 64.9 bits (151), Expect = 2e-10
Identities = 27/77 (35%), Positives = 42/77 (54%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G++V EC ++G P P + W+ I DF+ ++ G ARL I++ AED G +TC
Sbjct: 956 EGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTC 1015
Query: 65 EASNCLGKAKSNACLVV 81
A N G ++ L V
Sbjct: 1016 SAVNEAGTVSTSCYLAV 1032
Score = 62.9 bits (146), Expect = 8e-10
Identities = 37/102 (36%), Positives = 46/102 (45%), Gaps = 1/102 (0%)
Query: 84 TRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARIT 143
T + PG AP F T P + + EG +V F C V GNP P W K G +T R
Sbjct: 1070 TEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYK 1129
Query: 144 VKEKEEIMRI-LEIDEVSIEDVGIYRITVENELGRAEASARL 184
V ++ L I +D G Y I V N+ G ASA L
Sbjct: 1130 VSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1171
Score = 54.8 bits (126), Expect = 2e-07
Identities = 35/128 (27%), Positives = 63/128 (49%), Gaps = 4/128 (3%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+GD++ EC ++G P P + WF +++ F+ + + +L IK V ++D G Y C
Sbjct: 4172 EGDSIILECLISGEPQPVVTWFQNGVLLKQNQKFQFEEVNCSHQLYIKDVNSQDSGKYKC 4231
Query: 65 EASNCLGKAKSNACLVVYH-TRRLSSPGRQMAPTFYTYPFN-KVVEEGENVT--FKCAVK 120
A N G +S + L V T R +S + + Y + ++ ++GE+V F
Sbjct: 4232 VAENNSGAVESVSDLTVEPVTYRENSQFENIGEIYGKYSRDQQLQDQGESVRAHFYDYPA 4291
Query: 121 GNPSPWAS 128
G +PW +
Sbjct: 4292 GPFTPWTN 4299
Score = 54.0 bits (124), Expect = 4e-07
Identities = 24/64 (37%), Positives = 36/64 (56%), Gaps = 1/64 (1%)
Query: 11 FECQVTGNPDPDIRWF-HYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNC 69
F+C V G P P+++W+ Y + D + S + G+ LKI+ V D TY C A NC
Sbjct: 5399 FKCSVIGIPTPEVKWYKEYMCIEPDNIKYVISEEKGSHTLKIRNVCLSDSATYRCRAVNC 5458
Query: 70 LGKA 73
+G+A
Sbjct: 5459 VGEA 5462
Score = 53.6 bits (123), Expect = 5e-07
Identities = 31/87 (35%), Positives = 44/87 (50%), Gaps = 1/87 (1%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSY-DDGTARLKIKQVTAEDEGTYT 63
+G V F C+++G P P I W+ + I+ ++ + DG A L+I V EDEG YT
Sbjct: 1304 EGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYT 1363
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSP 90
ASN G A + L V L +P
Sbjct: 1364 AFASNIKGNAICSGKLYVEPAAPLGAP 1390
Score = 53.2 bits (122), Expect = 7e-07
Identities = 46/173 (26%), Positives = 70/173 (40%), Gaps = 16/173 (9%)
Query: 6 GDTVEFECQVTGNPDPDIRWF-HYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
G F +V G PDP+ W+ + ++ R + +D L I+ VTAED +
Sbjct: 2092 GSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMV 2151
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVV--EEGENVTFKCAVKGN 122
+A N G+ S+A L+V + ++ +T VV E+ TF+C
Sbjct: 2152 KAINIAGETSSHAFLLVQAKQLIT----------FTQELQDVVAKEKDTMATFECET-SE 2200
Query: 123 PSPWASWDKDGSII--TPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVEN 173
P W KDG + R+ K + IL ID ED + EN
Sbjct: 2201 PFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVEDEN 2253
Score = 52.8 bits (121), Expect = 9e-07
Identities = 31/94 (32%), Positives = 44/94 (46%), Gaps = 2/94 (2%)
Query: 96 PTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILE 155
P YP V EGE F+C V G P P +W +G +I S R V + + + L+
Sbjct: 1841 PDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRV--RYDGIHYLD 1898
Query: 156 IDEVSIEDVGIYRITVENELGRAEASARLEVITR 189
I + D G ++T EN G E +LE+ R
Sbjct: 1899 IVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQR 1932
Score = 49.6 bits (113), Expect = 8e-06
Identities = 30/91 (32%), Positives = 43/91 (47%), Gaps = 1/91 (1%)
Query: 96 PTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILE 155
PT + N V EGE+VT +C + G PSP +W ++ I S + + I R++
Sbjct: 943 PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLM- 1001
Query: 156 IDEVSIEDVGIYRITVENELGRAEASARLEV 186
I E ED G + + NE G S L V
Sbjct: 1002 IREAFAEDSGRFTCSAVNEAGTVSTSCYLAV 1032
Score = 48.0 bits (109), Expect = 3e-05
Identities = 28/81 (34%), Positives = 41/81 (50%), Gaps = 4/81 (4%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVI----RDCADFESSYDDGTARLKIKQVTAEDEG 60
+G+ V F C++ P P++ WFH I R ES ++ L+IK+V D G
Sbjct: 3517 EGEPVVFTCRLIACPTPEMTWFHNNRPIPTGLRRIIKAESDLHHHSSSLEIKRVQDRDSG 3576
Query: 61 TYTCEASNCLGKAKSNACLVV 81
+Y A N G A+S A L+V
Sbjct: 3577 SYRLLAINSEGSAESTASLLV 3597
Score = 47.6 bits (108), Expect = 3e-05
Identities = 30/83 (36%), Positives = 37/83 (44%)
Query: 104 NKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIED 163
N + EG VTF C + G P P +W KDG I R + ++ L I V ED
Sbjct: 1299 NYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPED 1358
Query: 164 VGIYRITVENELGRAEASARLEV 186
GIY N G A S +L V
Sbjct: 1359 EGIYTAFASNIKGNAICSGKLYV 1381
Score = 46.8 bits (106), Expect = 6e-05
Identities = 34/94 (36%), Positives = 46/94 (48%), Gaps = 3/94 (3%)
Query: 95 APTFYTYPFNKVVE-EGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRI 153
APTF T P VV EG TF+ + G P P SW +DG +I+ S V+ R
Sbjct: 5 APTF-TQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRA 63
Query: 154 -LEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
L I V+ + G Y + N G+A ++A L V
Sbjct: 64 KLTIPAVTKANSGRYSLKATNGSGQATSTAELLV 97
Score = 46.8 bits (106), Expect = 6e-05
Identities = 32/97 (32%), Positives = 45/97 (46%), Gaps = 3/97 (3%)
Query: 96 PTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMR--- 152
P+F K V EGE V F C + P+P +W + I R +K + ++
Sbjct: 3504 PSFTQKLTFKYVLEGEPVVFTCRLIACPTPEMTWFHNNRPIPTGLRRIIKAESDLHHHSS 3563
Query: 153 ILEIDEVSIEDVGIYRITVENELGRAEASARLEVITR 189
LEI V D G YR+ N G AE++A L VI +
Sbjct: 3564 SLEIKRVQDRDSGSYRLLAINSEGSAESTASLLVIQK 3600
Score = 44.8 bits (101), Expect = 2e-04
Identities = 25/78 (32%), Positives = 38/78 (48%), Gaps = 2/78 (2%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYD--DGTARLKIKQVTAEDEGTY 62
+G +V F CQV GNP P + W + ++ SY+ G +L I A+D G Y
Sbjct: 1095 EGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEY 1154
Query: 63 TCEASNCLGKAKSNACLV 80
T N G+ ++A L+
Sbjct: 1155 TIVVRNKHGETSASASLL 1172
Score = 44.8 bits (101), Expect = 2e-04
Identities = 31/112 (27%), Positives = 46/112 (41%), Gaps = 4/112 (3%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G+T F C+VTG P P + W+ ++IR F Y DG L I + D G
Sbjct: 1854 EGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRY-DGIHYLDIVDCKSYDTGEVKV 1912
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGR---QMAPTFYTYPFNKVVEEGENV 113
A N G + L + S R + P F+ + K+ E + V
Sbjct: 1913 TAENPEGVIEHKVKLEIQQREDFRSVLRRAPEPRPEFHVHEPGKLQFEVQKV 1964
Score = 44.8 bits (101), Expect = 2e-04
Identities = 21/78 (26%), Positives = 40/78 (51%), Gaps = 1/78 (1%)
Query: 109 EGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYR 168
EG+++ +C + G P P +W ++G ++ + + E+ L I +V+ +D G Y+
Sbjct: 4172 EGDSIILECLISGEPQPVVTWFQNGVLLKQNQKFQF-EEVNCSHQLYIKDVNSQDSGKYK 4230
Query: 169 ITVENELGRAEASARLEV 186
EN G E+ + L V
Sbjct: 4231 CVAENNSGAVESVSDLTV 4248
Score = 44.8 bits (101), Expect = 2e-04
Identities = 23/76 (30%), Positives = 35/76 (46%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G F+C V G+P P + W+ ++++ G L I + DEG Y C
Sbjct: 5528 GTAAYFQCLVRGSPRPTVYWYKDGKLVQGRRFTVEESGTGFHNLFITSLVKSDEGEYRCV 5587
Query: 66 ASNCLGKAKSNACLVV 81
A+N G A+S A L +
Sbjct: 5588 ATNKSGMAESFAALTL 5603
Score = 43.2 bits (97), Expect = 7e-04
Identities = 26/86 (30%), Positives = 38/86 (44%)
Query: 93 QMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMR 152
+M P F + + E + FKC+V G P+P W K+ I P V +E+
Sbjct: 5377 EMPPRFIMPICDFKIPENSDAVFKCSVIGIPTPEVKWYKEYMCIEPDNIKYVISEEKGSH 5436
Query: 153 ILEIDEVSIEDVGIYRITVENELGRA 178
L+I V + D YR N +G A
Sbjct: 5437 TLKIRNVCLSDSATYRCRAVNCVGEA 5462
Score = 41.1 bits (92), Expect = 0.003
Identities = 24/95 (25%), Positives = 45/95 (47%), Gaps = 1/95 (1%)
Query: 93 QMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMR 152
+M P+F + V E + F V+G P P W ++ S++ P RI ++ +
Sbjct: 5180 EMPPSFIEPLTKRKVYENTTLGFIVEVEGLPVPGVKWYRNKSLLEPDERIKMERVGNVCS 5239
Query: 153 ILEIDEVSIEDVGIYRITVENELGRAEASARLEVI 187
LEI + + G Y N +G A++ A ++++
Sbjct: 5240 -LEISNIQKGEGGEYMCHAVNIIGEAKSFANVDIM 5273
Score = 40.7 bits (91), Expect = 0.004
Identities = 28/95 (29%), Positives = 37/95 (38%)
Query: 92 RQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIM 151
R P F P + EG+ F V G P P W DG I V KE+
Sbjct: 1453 RLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGT 1512
Query: 152 RILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
+ L I + D G + + +N GR+ S L V
Sbjct: 1513 QSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTV 1547
Score = 39.9 bits (89), Expect = 0.007
Identities = 24/97 (24%), Positives = 43/97 (44%), Gaps = 1/97 (1%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+GD+ F C G P P + W++ I +F + + L + V ++EG+ TC
Sbjct: 3957 EGDSCNFVCHFQGYPQPIVTWYNNDMPIPRNQNFIIHSLENYSILTLSSVHHQNEGSITC 4016
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTY 101
N G K+ + L V ++ ++ P F+ Y
Sbjct: 4017 VLFNQYGTVKTTSMLKVKAKQKHDVKAHKV-PVFHDY 4052
Score = 39.5 bits (88), Expect = 0.009
Identities = 19/73 (26%), Positives = 33/73 (45%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+ T+ F +V G P P ++W+ ++ + L+I + + G Y C
Sbjct: 5196 ENTTLGFIVEVEGLPVPGVKWYRNKSLLEPDERIKMERVGNVCSLEISNIQKGEGGEYMC 5255
Query: 65 EASNCLGKAKSNA 77
A N +G+AKS A
Sbjct: 5256 HAVNIIGEAKSFA 5268
Score = 38.3 bits (85), Expect = 0.021
Identities = 22/80 (27%), Positives = 35/80 (43%), Gaps = 1/80 (1%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
V+ G+ F + G P P SW K+ +++ + + +L I E ED +
Sbjct: 3250 VQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLI-EAFPEDAAV 3308
Query: 167 YRITVENELGRAEASARLEV 186
Y +N+ G A SA L V
Sbjct: 3309 YTCEAKNDYGVATTSASLSV 3328
Score = 37.9 bits (84), Expect = 0.027
Identities = 29/98 (29%), Positives = 43/98 (43%), Gaps = 1/98 (1%)
Query: 89 SPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKE 148
SP + AP + ++ V +G + F+ V G P P W K+G I S RI E
Sbjct: 2072 SPSME-APKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPE 2130
Query: 149 EIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
+ + L I +V+ ED + N G + A L V
Sbjct: 2131 DNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLV 2168
Score = 36.7 bits (81), Expect = 0.063
Identities = 40/162 (24%), Positives = 69/162 (42%), Gaps = 17/162 (10%)
Query: 10 EFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNC 69
E EC V+ + + +W+H ++ + + G L +K VT ED+G Y+
Sbjct: 2285 ELECIVSPE-NIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVID-- 2341
Query: 70 LGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASW 129
K C +L R +A ++ V EG+ V + V S W
Sbjct: 2342 ---GKKTTC-------KLKMKPRPIA--ILQGLSDQKVCEGDIVQLEVKV-SLESVEGVW 2388
Query: 130 DKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITV 171
KDG + PS R+ + ++ +L I++++ ED G Y T+
Sbjct: 2389 MKDGQEVQPSDRVHIVIDKQ-SHMLLIEDMTKEDAGNYSFTI 2429
Score = 36.3 bits (80), Expect = 0.084
Identities = 21/79 (26%), Positives = 34/79 (43%), Gaps = 2/79 (2%)
Query: 11 FECQVT--GNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
FEC++T G+P + W H + + + G L + D G TC A+N
Sbjct: 1722 FECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATN 1781
Query: 69 CLGKAKSNACLVVYHTRRL 87
G ++A L+V + L
Sbjct: 1782 KYGTDHTSATLIVKDEKSL 1800
Score = 35.9 bits (79), Expect = 0.11
Identities = 45/178 (25%), Positives = 69/178 (38%), Gaps = 22/178 (12%)
Query: 11 FECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCL 70
FEC+V NPD W + + + S D RL I +D G YT + +
Sbjct: 2639 FECEVA-NPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTYKVAT-- 2695
Query: 71 GKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWD 130
+K++A +L ++ T N V E ++ F + W
Sbjct: 2696 --SKTSA--------KLKVEAVKIKKTLK----NLTVTETQDAVFTVELTHPNVKGVQWI 2741
Query: 131 KDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVIT 188
K+G ++ + + + K I L I +I D +Y LGR ASARL V T
Sbjct: 2742 KNGVVLESNEKYAISVKGTIYS-LRIKNCAIVDESVYGF----RLGRLGASARLHVET 2794
Score = 33.9 bits (74), Expect = 0.45
Identities = 21/91 (23%), Positives = 40/91 (43%), Gaps = 1/91 (1%)
Query: 96 PTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILE 155
P+F ++ V EG++ F C +G P P +W + I + + E IL
Sbjct: 3944 PSFLQEIESQEVYEGDSCNFVCHFQGYPQPIVTWYNNDMPIPRNQNFIIHSLEN-YSILT 4002
Query: 156 IDEVSIEDVGIYRITVENELGRAEASARLEV 186
+ V ++ G + N+ G + ++ L+V
Sbjct: 4003 LSSVHHQNEGSITCVLFNQYGTVKTTSMLKV 4033
>X69490-1|CAA49245.1| 4650|Homo sapiens titin protein.
Length = 4650
Score = 86.6 bits (205), Expect = 6e-17
Identities = 55/185 (29%), Positives = 81/185 (43%), Gaps = 7/185 (3%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSY----DDGTARLKIKQVTAEDEGT 61
G+ V F +T +P+P + W+ + I+ D + Y D G +L I VT +D+
Sbjct: 2931 GENVRFGVTITVHPEPHVTWYKSGQKIKP-GDNDKKYTFESDKGLYQLTINSVTTDDDAE 2989
Query: 62 YTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKG 121
YT A N G+ A L V T + P F N +EG++V F+ V G
Sbjct: 2990 YTVVARNKYGEDSCKAKLTV--TLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSG 3047
Query: 122 NPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEAS 181
P P W+KDG ++ I + + L I + ED G YR+T N G
Sbjct: 3048 IPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQ 3107
Query: 182 ARLEV 186
A L+V
Sbjct: 3108 AHLQV 3112
Score = 77.4 bits (182), Expect = 4e-14
Identities = 54/202 (26%), Positives = 91/202 (45%), Gaps = 20/202 (9%)
Query: 5 DGDTVEFECQVTG-NPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYT 63
+G V++ C++ + + W+ + + +E +Y+DG A L +K +T D+GTY
Sbjct: 2808 EGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYR 2867
Query: 64 CEASNCLGKAKSNACLVV--------YHTRRLSSPGRQMAPTF--------YTYP-FNKV 106
C+ N G+ S A L V Y+ RR ++ T +T P +NK
Sbjct: 2868 CKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNKT 2927
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITP--SARITVKEKEEIMRILEIDEVSIEDV 164
GENV F + +P P +W K G I P + + E ++ + L I+ V+ +D
Sbjct: 2928 AYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDD 2987
Query: 165 GIYRITVENELGRAEASARLEV 186
Y + N+ G A+L V
Sbjct: 2988 AEYTVVARNKYGEDSCKAKLTV 3009
Score = 76.6 bits (180), Expect = 6e-14
Identities = 44/187 (23%), Positives = 83/187 (44%), Gaps = 8/187 (4%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+ + CQ+ G P PDI+W+ + + + ++ S D T L + EDEG YTC
Sbjct: 1774 GEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCI 1833
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A+N +G+ ++++ L++ T + PG + +Y G + G P P
Sbjct: 1834 ATNEVGEVETSSKLLLQATPQF-HPGYPLKEKYYG-------AVGSTLRLHVMYIGRPVP 1885
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
+W ++ S IT++ E ++ + G Y++ + N G +A +E
Sbjct: 1886 AMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVE 1945
Query: 186 VITRSGK 192
+ + K
Sbjct: 1946 IQDKPDK 1952
Score = 73.7 bits (173), Expect = 5e-13
Identities = 47/166 (28%), Positives = 76/166 (45%), Gaps = 8/166 (4%)
Query: 22 DIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLGKAKSNACLVV 81
D++W + + ++ L IKQ + DEG TC + G K L +
Sbjct: 4294 DVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTL 4353
Query: 82 YHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSAR 141
++ LS AP F + P ++ + EG+NV F + G PSP W K+ I+ S+
Sbjct: 4354 --SKELSD-----APAFISQPRSQNINEGQNVLFTREISGEPSPEIEWFKNNLPISISSN 4406
Query: 142 ITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVI 187
+++ + LEI S+ D G Y I +N G+ A+A L V+
Sbjct: 4407 VSISRSRNVYS-LEIRNASVSDSGKYTIKAKNFRGQCSATASLMVL 4451
Score = 58.8 bits (136), Expect = 1e-08
Identities = 43/176 (24%), Positives = 72/176 (40%), Gaps = 8/176 (4%)
Query: 13 CQVTGNPDPDIRWFHYA-EVIRDCADFE-SSYDDGTARLKIKQVTAEDEGTYTCEASNCL 70
C+VTG+P P ++W+ E+I D + + G +L I VT +D Y A+N
Sbjct: 2176 CKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQG 2235
Query: 71 GKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWD 130
G A L V ++ P + + + GE V+ K G P P +W
Sbjct: 2236 GSVSGTASLEVEVPAKIHLP-KTLEGMGAVHALR-----GEVVSIKIPFSGKPDPVITWQ 2289
Query: 131 KDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
K +I + V ++ + V +D G Y + +N G + + L+V
Sbjct: 2290 KGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDV 2345
Score = 56.4 bits (130), Expect = 7e-08
Identities = 31/93 (33%), Positives = 43/93 (46%), Gaps = 1/93 (1%)
Query: 94 MAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRI 153
+A T P + V EGE+ F C G P P +W + G +++ SAR V +
Sbjct: 3786 LAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGRVLSTSARHQV-TTTKYKST 3844
Query: 154 LEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
EI V D G Y + VEN G+ EA L +
Sbjct: 3845 FEISSVQASDEGNYSVVVENSEGKQEAEFTLTI 3877
Score = 49.2 bits (112), Expect = 1e-05
Identities = 35/157 (22%), Positives = 69/157 (43%), Gaps = 7/157 (4%)
Query: 36 ADFESSYDDGTARLKIKQVTAEDEGTYT---CEASNCLGKAKSNACLVVYHTRRLSSPG- 91
+ F SS +K ++A+ + E S+ SN + T ++ G
Sbjct: 4492 SSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMTQLESSTSKMLKAGI 4551
Query: 92 RQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSII--TPSARITVKEKEE 149
R + P P + ++EG+ +T CA G P+P +W G I R ++ ++
Sbjct: 4552 RGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDD 4611
Query: 150 IMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
+ ++ +D V +D G+Y +++ NE G A+ + +
Sbjct: 4612 LTTLIIMD-VQKQDGGLYTLSLGNEFGSDSATVNIHI 4647
Score = 47.2 bits (107), Expect = 4e-05
Identities = 25/96 (26%), Positives = 41/96 (42%), Gaps = 4/96 (4%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G++ F C G P P + W V+ A + + + +I V A DEG Y+
Sbjct: 3801 EGESARFSCDTDGEPVPTVTWLRKGRVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSV 3860
Query: 65 EASNCLGKAKSNACLVVYHTR----RLSSPGRQMAP 96
N GK ++ L + R ++SP R +P
Sbjct: 3861 VVENSEGKQEAEFTLTIQKARVTEKAVTSPPRVKSP 3896
Score = 47.2 bits (107), Expect = 4e-05
Identities = 27/73 (36%), Positives = 36/73 (49%), Gaps = 3/73 (4%)
Query: 116 KCAVK--GNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVEN 173
K AVK G P P A W KDG IT + + E + LEI + D G+Y TV+N
Sbjct: 4097 KFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGF-FLEIHKTDTSDSGLYTCTVKN 4155
Query: 174 ELGRAEASARLEV 186
G +S +L +
Sbjct: 4156 SAGSVSSSCKLTI 4168
Score = 46.8 bits (106), Expect = 6e-05
Identities = 23/77 (29%), Positives = 37/77 (48%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G V F +++G P P+I WF I ++ S L+I+ + D G YT
Sbjct: 4374 EGQNVLFTREISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTI 4433
Query: 65 EASNCLGKAKSNACLVV 81
+A N G+ + A L+V
Sbjct: 4434 KAKNFRGQCSATASLMV 4450
Score = 45.2 bits (102), Expect = 2e-04
Identities = 26/92 (28%), Positives = 45/92 (48%), Gaps = 1/92 (1%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
V G V + G P P ASW GS + S R+TV+ ++ + L I E +I D G
Sbjct: 977 VPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAK-LTIRETTIRDTGE 1035
Query: 167 YRITVENELGRAEASARLEVITRSGKFYGGLR 198
Y + ++N G + ++ ++ + G G ++
Sbjct: 1036 YTLELKNVTGTTLETIKVIILDKPGPPTGPIK 1067
Score = 44.4 bits (100), Expect = 3e-04
Identities = 28/93 (30%), Positives = 41/93 (44%), Gaps = 1/93 (1%)
Query: 95 APTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDG-SIITPSARITVKEKEEIMRI 153
AP F N V N T C V G+P P W + G II + ++E +
Sbjct: 2154 APHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQ 2213
Query: 154 LEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
L I V+ +D +Y++ N+ G +A LEV
Sbjct: 2214 LIIASVTDDDATVYQVRATNQGGSVSGTASLEV 2246
Score = 42.7 bits (96), Expect = 0.001
Identities = 19/56 (33%), Positives = 31/56 (55%), Gaps = 1/56 (1%)
Query: 22 DIRWFHYAEVIRDCADFESSYD-DGTARLKIKQVTAEDEGTYTCEASNCLGKAKSN 76
++ W+ + +++ F+ Y DGT LKI +T D+G Y CE S G +K+N
Sbjct: 3975 EVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTN 4030
Score = 42.3 bits (95), Expect = 0.001
Identities = 24/85 (28%), Positives = 39/85 (45%), Gaps = 3/85 (3%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
+ G ++ +V G P P +W K G + A I E + L +D+V+ D G
Sbjct: 685 IRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSL---LIVDKVNRYDAGK 741
Query: 167 YRITVENELGRAEASARLEVITRSG 191
Y I EN+ G+ A+ ++V G
Sbjct: 742 YTIEAENQSGKKSATVLVKVYDTPG 766
Score = 42.3 bits (95), Expect = 0.001
Identities = 24/81 (29%), Positives = 36/81 (44%), Gaps = 3/81 (3%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
V +G + +KG P P W K+G I+ A I E + I E D D G
Sbjct: 1375 VRQGGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETHTELVIKEADR---GDSGT 1431
Query: 167 YRITVENELGRAEASARLEVI 187
Y + +EN+ G+ ++ VI
Sbjct: 1432 YDLVLENKCGKKAVYIKVRVI 1452
Score = 42.3 bits (95), Expect = 0.001
Identities = 21/72 (29%), Positives = 30/72 (41%)
Query: 10 EFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNC 69
+F + TG P P W + I ++ S D G L+I + D G YTC N
Sbjct: 4097 KFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNS 4156
Query: 70 LGKAKSNACLVV 81
G S+ L +
Sbjct: 4157 AGSVSSSCKLTI 4168
Score = 40.3 bits (90), Expect = 0.005
Identities = 24/91 (26%), Positives = 33/91 (36%), Gaps = 5/91 (5%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G VE + G P P WF +R+ A+L I++ T D G YT E
Sbjct: 980 GRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLE 1039
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAP 96
N G +++ L PG P
Sbjct: 1040 LKNVTGTTLETIKVII-----LDKPGPPTGP 1065
Score = 38.3 bits (85), Expect = 0.021
Identities = 18/76 (23%), Positives = 31/76 (40%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G F V P +++W+H +++ + + G L+I +D GTY
Sbjct: 3615 GQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAV 3674
Query: 66 ASNCLGKAKSNACLVV 81
+N G+ A L V
Sbjct: 3675 CTNYKGERSDYATLDV 3690
Score = 35.1 bits (77), Expect = 0.19
Identities = 22/79 (27%), Positives = 35/79 (44%), Gaps = 2/79 (2%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G ++ V+G P P I W + A +++ + + L + +V D G YT E
Sbjct: 688 GASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTT--ESYSLLIVDKVNRYDAGKYTIE 745
Query: 66 ASNCLGKAKSNACLVVYHT 84
A N GK + + VY T
Sbjct: 746 AENQSGKKSATVLVKVYDT 764
Score = 35.1 bits (77), Expect = 0.19
Identities = 23/82 (28%), Positives = 36/82 (43%), Gaps = 1/82 (1%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDD-GTARLKIKQVTAEDEGTYT 63
+G +V FE +V+G P P ++W + + + E ++ L I+ ED G Y
Sbjct: 3035 EGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYR 3094
Query: 64 CEASNCLGKAKSNACLVVYHTR 85
A+N G A L V R
Sbjct: 3095 VTATNTAGSTSCQAHLQVERLR 3116
Score = 34.7 bits (76), Expect = 0.26
Identities = 25/96 (26%), Positives = 37/96 (38%), Gaps = 1/96 (1%)
Query: 110 GENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRI 169
G+N F V+ P+ W +G + S++I ++ LEI + +D G YR
Sbjct: 3615 GQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLT-LEILDCHTDDSGTYRA 3673
Query: 170 TVENELGRAEASARLEVITRSGKFYGGLRAYSASPR 205
N G A L+V Y R PR
Sbjct: 3674 VCTNYKGERSDYATLDVTGGDYTTYASQRRDEEVPR 3709
Score = 33.1 bits (72), Expect = 0.78
Identities = 23/85 (27%), Positives = 33/85 (38%), Gaps = 5/85 (5%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVI--RDCADFESSYDDGTARLKIKQVTAEDEGTY 62
+G + C TG P P++ W I ++ F D L I V +D G Y
Sbjct: 4569 EGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLY 4628
Query: 63 TCEASNCLGKAKSNACLVVYHTRRL 87
T N G S++ V H R +
Sbjct: 4629 TLSLGNEFG---SDSATVNIHIRSI 4650
Score = 31.9 bits (69), Expect = 1.8
Identities = 23/102 (22%), Positives = 43/102 (42%), Gaps = 4/102 (3%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVK-EKEEIMRILEIDEVSIEDVG 165
+ G ++ AV G P P W K + +++++ + +++ + S D G
Sbjct: 286 IRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRS--DSG 343
Query: 166 IYRITVENELGRAEASARLEVITRSGKFYGGLRAYSASPRKC 207
Y +TV+N G S ++V+ G G L + KC
Sbjct: 344 KYTLTVKNASGTKAVSVMVKVLDSPGP-CGKLTVSRVTQEKC 384
Score = 31.5 bits (68), Expect = 2.4
Identities = 24/86 (27%), Positives = 33/86 (38%), Gaps = 5/86 (5%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G + + V G P+P I W + + C Y A IK D G YT
Sbjct: 289 GSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLT 348
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPG 91
N G K+ + +V + L SPG
Sbjct: 349 VKNASG-TKAVSVMV----KVLDSPG 369
>BC115022-1|AAI15023.1| 1551|Homo sapiens ROBO1 protein protein.
Length = 1551
Score = 85.0 bits (201), Expect = 2e-16
Identities = 68/189 (35%), Positives = 93/189 (49%), Gaps = 26/189 (13%)
Query: 7 DTVEFECQVTGNPDPDIRWFHY-AEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
D+ EF+C+ G+P P +RW E+ + + DD T LKI++VTA D G+YTC
Sbjct: 238 DSAEFKCEARGDPVPTVRWRKDDGELPKSRYEIR---DDHT--LKIRKVTAGDMGSYTCV 292
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A N +GKA+++A L V + S P P F P ++VV G VTF+C GNP P
Sbjct: 293 AENMVGKAEASATLTV---QVGSEP-----PHFVVKPRDQVVALGRTVTFQCEATGNPQP 344
Query: 126 WASWDKDGS-----IITP---SARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGR 177
W ++GS P S+R +V + + L I V DVG Y N G
Sbjct: 345 AIFWRREGSQNLLFSYQPPQSSSRFSVSQTGD----LTITNVQRSDVGYYICQTLNVAGS 400
Query: 178 AEASARLEV 186
A LEV
Sbjct: 401 IITKAYLEV 409
Score = 73.7 bits (173), Expect = 5e-13
Identities = 54/182 (29%), Positives = 81/182 (44%), Gaps = 19/182 (10%)
Query: 6 GDTVEFECQVT-GNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
G+ ECQ G+P+P I W + D D + G +L I D G Y C
Sbjct: 145 GEPAVMECQPPRGHPEPTISWKKDGSPLDD-KDERITIRGG--KLMITYTRKSDAGKYVC 201
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
+N +G+ +S + R P+F P N V ++ FKC +G+P
Sbjct: 202 VGTNMVGERESEVAELTVLER----------PSFVKRPSNLAVTVDDSAEFKCEARGDPV 251
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
P W KD + P +R +++ L+I +V+ D+G Y EN +G+AEASA L
Sbjct: 252 PTVRWRKDDGEL-PKSRYEIRDD----HTLKIRKVTAGDMGSYTCVAENMVGKAEASATL 306
Query: 185 EV 186
V
Sbjct: 307 TV 308
Score = 63.7 bits (148), Expect = 5e-10
Identities = 56/187 (29%), Positives = 73/187 (39%), Gaps = 15/187 (8%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYA--EVIRDCADFESSYD---DGTARLKIKQVTAEDEG 60
G TV F+C+ TGNP P I W ++ +SS T L I V D G
Sbjct: 329 GRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVG 388
Query: 61 TYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVK 120
Y C+ N G + A L V P P P N+ V C
Sbjct: 389 YYICQTLNVAGSIITKAYLEVTDVIADRPP-----PVIRQGPVNQTVAVDGTFVLSCVAT 443
Query: 121 GNPSPWASWDKDGSII-TPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAE 179
G+P P W KDG ++ T +RI K+ E +L+I + D G Y G A
Sbjct: 444 GSPVPTILWRKDGVLVSTQDSRI--KQLEN--GVLQIRYAKLGDTGRYTCIASTPSGEAT 499
Query: 180 ASARLEV 186
SA +EV
Sbjct: 500 WSAYIEV 506
Score = 56.0 bits (129), Expect = 1e-07
Identities = 58/195 (29%), Positives = 80/195 (41%), Gaps = 26/195 (13%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSY----DDGTA---RLKIKQVTAED 58
G+ C+ G P P I W+ E + D S+ G+ R+ + + D
Sbjct: 43 GEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKSRPD 102
Query: 59 EGTYTCEASNCLGKAKS-NACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKC 117
EG Y C A N LG+A S NA L V R F P + +V GE +C
Sbjct: 103 EGVYVCVARNYLGEAVSHNASLEVAILR----------DDFRQNPSDVMVVVGEPAVMEC 152
Query: 118 -AVKGNPSPWASWDKDGS-IITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENEL 175
+G+P P SW KDGS + RIT++ + L I D G Y N +
Sbjct: 153 QPPRGHPEPTISWKKDGSPLDDKDERITIRGGK-----LMITYTRKSDAGKYVCVGTNMV 207
Query: 176 GRAEAS-ARLEVITR 189
G E+ A L V+ R
Sbjct: 208 GERESEVAELTVLER 222
Score = 37.9 bits (84), Expect = 0.027
Identities = 27/98 (27%), Positives = 40/98 (40%), Gaps = 7/98 (7%)
Query: 96 PTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITP------SARITVKEKEE 149
P +P + +V +GE T C +G P+P W K G + S R+ +
Sbjct: 29 PRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSL 88
Query: 150 IMRILEIDEVSIEDVGIYRITVENELGRAEA-SARLEV 186
+ S D G+Y N LG A + +A LEV
Sbjct: 89 FFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEV 126
>BC115020-1|AAI15021.1| 1606|Homo sapiens ROBO1 protein protein.
Length = 1606
Score = 85.0 bits (201), Expect = 2e-16
Identities = 68/189 (35%), Positives = 93/189 (49%), Gaps = 26/189 (13%)
Query: 7 DTVEFECQVTGNPDPDIRWFHY-AEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
D+ EF+C+ G+P P +RW E+ + + DD T LKI++VTA D G+YTC
Sbjct: 238 DSAEFKCEARGDPVPTVRWRKDDGELPKSRYEIR---DDHT--LKIRKVTAGDMGSYTCV 292
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A N +GKA+++A L V + S P P F P ++VV G VTF+C GNP P
Sbjct: 293 AENMVGKAEASATLTV---QVGSEP-----PHFVVKPRDQVVALGRTVTFQCEATGNPQP 344
Query: 126 WASWDKDGS-----IITP---SARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGR 177
W ++GS P S+R +V + + L I V DVG Y N G
Sbjct: 345 AIFWRREGSQNLLFSYQPPQSSSRFSVSQTGD----LTITNVQRSDVGYYICQTLNVAGS 400
Query: 178 AEASARLEV 186
A LEV
Sbjct: 401 IITKAYLEV 409
Score = 73.7 bits (173), Expect = 5e-13
Identities = 54/182 (29%), Positives = 81/182 (44%), Gaps = 19/182 (10%)
Query: 6 GDTVEFECQVT-GNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
G+ ECQ G+P+P I W + D D + G +L I D G Y C
Sbjct: 145 GEPAVMECQPPRGHPEPTISWKKDGSPLDD-KDERITIRGG--KLMITYTRKSDAGKYVC 201
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
+N +G+ +S + R P+F P N V ++ FKC +G+P
Sbjct: 202 VGTNMVGERESEVAELTVLER----------PSFVKRPSNLAVTVDDSAEFKCEARGDPV 251
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
P W KD + P +R +++ L+I +V+ D+G Y EN +G+AEASA L
Sbjct: 252 PTVRWRKDDGEL-PKSRYEIRDD----HTLKIRKVTAGDMGSYTCVAENMVGKAEASATL 306
Query: 185 EV 186
V
Sbjct: 307 TV 308
Score = 63.7 bits (148), Expect = 5e-10
Identities = 56/187 (29%), Positives = 73/187 (39%), Gaps = 15/187 (8%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYA--EVIRDCADFESSYD---DGTARLKIKQVTAEDEG 60
G TV F+C+ TGNP P I W ++ +SS T L I V D G
Sbjct: 329 GRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVG 388
Query: 61 TYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVK 120
Y C+ N G + A L V P P P N+ V C
Sbjct: 389 YYICQTLNVAGSIITKAYLEVTDVIADRPP-----PVIRQGPVNQTVAVDGTFVLSCVAT 443
Query: 121 GNPSPWASWDKDGSII-TPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAE 179
G+P P W KDG ++ T +RI K+ E +L+I + D G Y G A
Sbjct: 444 GSPVPTILWRKDGVLVSTQDSRI--KQLEN--GVLQIRYAKLGDTGRYTCIASTPSGEAT 499
Query: 180 ASARLEV 186
SA +EV
Sbjct: 500 WSAYIEV 506
Score = 56.4 bits (130), Expect = 7e-08
Identities = 58/195 (29%), Positives = 80/195 (41%), Gaps = 26/195 (13%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSY----DDGTA---RLKIKQVTAED 58
G+ C+ G P P I W+ E + D S+ G+ R+ + + D
Sbjct: 43 GEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKSRPD 102
Query: 59 EGTYTCEASNCLGKAKS-NACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKC 117
EG Y C A N LG+A S NA L V R F P + +V GE +C
Sbjct: 103 EGVYVCVARNYLGEAVSHNASLEVAILR----------DDFRQNPSDVMVAVGEPAVMEC 152
Query: 118 -AVKGNPSPWASWDKDGS-IITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENEL 175
+G+P P SW KDGS + RIT++ + L I D G Y N +
Sbjct: 153 QPPRGHPEPTISWKKDGSPLDDKDERITIRGGK-----LMITYTRKSDAGKYVCVGTNMV 207
Query: 176 GRAEAS-ARLEVITR 189
G E+ A L V+ R
Sbjct: 208 GERESEVAELTVLER 222
Score = 37.9 bits (84), Expect = 0.027
Identities = 27/98 (27%), Positives = 40/98 (40%), Gaps = 7/98 (7%)
Query: 96 PTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITP------SARITVKEKEE 149
P +P + +V +GE T C +G P+P W K G + S R+ +
Sbjct: 29 PRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSL 88
Query: 150 IMRILEIDEVSIEDVGIYRITVENELGRAEA-SARLEV 186
+ S D G+Y N LG A + +A LEV
Sbjct: 89 FFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEV 126
>BC112336-1|AAI12337.1| 1607|Homo sapiens ROBO1 protein protein.
Length = 1607
Score = 85.0 bits (201), Expect = 2e-16
Identities = 68/189 (35%), Positives = 93/189 (49%), Gaps = 26/189 (13%)
Query: 7 DTVEFECQVTGNPDPDIRWFHY-AEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
D+ EF+C+ G+P P +RW E+ + + DD T LKI++VTA D G+YTC
Sbjct: 238 DSAEFKCEARGDPVPTVRWRKDDGELPKSRYEIR---DDHT--LKIRKVTAGDMGSYTCV 292
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A N +GKA+++A L V + S P P F P ++VV G VTF+C GNP P
Sbjct: 293 AENMVGKAEASATLTV---QVGSEP-----PHFVVKPRDQVVALGRTVTFQCEATGNPQP 344
Query: 126 WASWDKDGS-----IITP---SARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGR 177
W ++GS P S+R +V + + L I V DVG Y N G
Sbjct: 345 AIFWRREGSQNLLFSYQPPQSSSRFSVSQTGD----LTITNVQRSDVGYYICQTLNVAGS 400
Query: 178 AEASARLEV 186
A LEV
Sbjct: 401 IITKAYLEV 409
Score = 73.7 bits (173), Expect = 5e-13
Identities = 54/182 (29%), Positives = 81/182 (44%), Gaps = 19/182 (10%)
Query: 6 GDTVEFECQVT-GNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
G+ ECQ G+P+P I W + D D + G +L I D G Y C
Sbjct: 145 GEPAVMECQPPRGHPEPTISWKKDGSPLDD-KDERITIRGG--KLMITYTRKSDAGKYVC 201
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
+N +G+ +S + R P+F P N V ++ FKC +G+P
Sbjct: 202 VGTNMVGERESEVAELTVLER----------PSFVKRPSNLAVTVDDSAEFKCEARGDPV 251
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
P W KD + P +R +++ L+I +V+ D+G Y EN +G+AEASA L
Sbjct: 252 PTVRWRKDDGEL-PKSRYEIRDD----HTLKIRKVTAGDMGSYTCVAENMVGKAEASATL 306
Query: 185 EV 186
V
Sbjct: 307 TV 308
Score = 63.7 bits (148), Expect = 5e-10
Identities = 56/187 (29%), Positives = 73/187 (39%), Gaps = 15/187 (8%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYA--EVIRDCADFESSYD---DGTARLKIKQVTAEDEG 60
G TV F+C+ TGNP P I W ++ +SS T L I V D G
Sbjct: 329 GRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVG 388
Query: 61 TYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVK 120
Y C+ N G + A L V P P P N+ V C
Sbjct: 389 YYICQTLNVAGSIITKAYLEVTDVIADRPP-----PVIRQGPVNQTVAVDGTFVLSCVAT 443
Query: 121 GNPSPWASWDKDGSII-TPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAE 179
G+P P W KDG ++ T +RI K+ E +L+I + D G Y G A
Sbjct: 444 GSPVPTILWRKDGVLVSTQDSRI--KQLEN--GVLQIRYAKLGDTGRYTCIASTPSGEAT 499
Query: 180 ASARLEV 186
SA +EV
Sbjct: 500 WSAYIEV 506
Score = 56.4 bits (130), Expect = 7e-08
Identities = 58/195 (29%), Positives = 80/195 (41%), Gaps = 26/195 (13%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSY----DDGTA---RLKIKQVTAED 58
G+ C+ G P P I W+ E + D S+ G+ R+ + + D
Sbjct: 43 GEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKSRPD 102
Query: 59 EGTYTCEASNCLGKAKS-NACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKC 117
EG Y C A N LG+A S NA L V R F P + +V GE +C
Sbjct: 103 EGVYVCVARNYLGEAVSHNASLEVAILR----------DDFRQNPSDVMVAVGEPAVMEC 152
Query: 118 -AVKGNPSPWASWDKDGS-IITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENEL 175
+G+P P SW KDGS + RIT++ + L I D G Y N +
Sbjct: 153 QPPRGHPEPTISWKKDGSPLDDKDERITIRGGK-----LMITYTRKSDAGKYVCVGTNMV 207
Query: 176 GRAEAS-ARLEVITR 189
G E+ A L V+ R
Sbjct: 208 GERESEVAELTVLER 222
Score = 37.9 bits (84), Expect = 0.027
Identities = 27/98 (27%), Positives = 40/98 (40%), Gaps = 7/98 (7%)
Query: 96 PTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITP------SARITVKEKEE 149
P +P + +V +GE T C +G P+P W K G + S R+ +
Sbjct: 29 PRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSL 88
Query: 150 IMRILEIDEVSIEDVGIYRITVENELGRAEA-SARLEV 186
+ S D G+Y N LG A + +A LEV
Sbjct: 89 FFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEV 126
>AF040990-1|AAC39575.1| 1651|Homo sapiens roundabout 1 protein.
Length = 1651
Score = 85.0 bits (201), Expect = 2e-16
Identities = 67/189 (35%), Positives = 91/189 (48%), Gaps = 29/189 (15%)
Query: 7 DTVEFECQVTGNPDPDIRWFHY-AEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
D+ EF+C+ G+P P +RW E+ + + DD T LKI++VTA D G+YTC
Sbjct: 277 DSAEFKCEARGDPVPTVRWRKDDGELPKSRYEIR---DDHT--LKIRKVTAGDMGSYTCV 331
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A N +GKA+++A L V Q P F P ++VV G VTF+C GNP P
Sbjct: 332 AENMVGKAEASATLTV-----------QEPPHFVVKPRDQVVALGRTVTFQCEATGNPQP 380
Query: 126 WASWDKDGS-----IITP---SARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGR 177
W ++GS P S+R +V + + L I V DVG Y N G
Sbjct: 381 AIFWRREGSQNLLFSYQPPQSSSRFSVSQTGD----LTITNVQRSDVGYYICQTLNVAGS 436
Query: 178 AEASARLEV 186
A LEV
Sbjct: 437 IITKAYLEV 445
Score = 73.7 bits (173), Expect = 5e-13
Identities = 54/182 (29%), Positives = 81/182 (44%), Gaps = 19/182 (10%)
Query: 6 GDTVEFECQVT-GNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
G+ ECQ G+P+P I W + D D + G +L I D G Y C
Sbjct: 184 GEPAVMECQPPRGHPEPTISWKKDGSPLDD-KDERITIRGG--KLMITYTRKSDAGKYVC 240
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
+N +G+ +S + R P+F P N V ++ FKC +G+P
Sbjct: 241 VGTNMVGERESEVAELTVLER----------PSFVKRPSNLAVTVDDSAEFKCEARGDPV 290
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
P W KD + P +R +++ L+I +V+ D+G Y EN +G+AEASA L
Sbjct: 291 PTVRWRKDDGEL-PKSRYEIRDD----HTLKIRKVTAGDMGSYTCVAENMVGKAEASATL 345
Query: 185 EV 186
V
Sbjct: 346 TV 347
Score = 63.7 bits (148), Expect = 5e-10
Identities = 56/187 (29%), Positives = 73/187 (39%), Gaps = 15/187 (8%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYA--EVIRDCADFESSYD---DGTARLKIKQVTAEDEG 60
G TV F+C+ TGNP P I W ++ +SS T L I V D G
Sbjct: 365 GRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVG 424
Query: 61 TYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVK 120
Y C+ N G + A L V P P P N+ V C
Sbjct: 425 YYICQTLNVAGSIITKAYLEVTDVIADRPP-----PVIRQGPVNQTVAVDGTFVLSCVAT 479
Query: 121 GNPSPWASWDKDGSII-TPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAE 179
G+P P W KDG ++ T +RI K+ E +L+I + D G Y G A
Sbjct: 480 GSPVPTILWRKDGVLVSTQDSRI--KQLEN--GVLQIRYAKLGDTGRYTCIASTPSGEAT 535
Query: 180 ASARLEV 186
SA +EV
Sbjct: 536 WSAYIEV 542
Score = 56.4 bits (130), Expect = 7e-08
Identities = 58/195 (29%), Positives = 80/195 (41%), Gaps = 26/195 (13%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSY----DDGTA---RLKIKQVTAED 58
G+ C+ G P P I W+ E + D S+ G+ R+ + + D
Sbjct: 82 GEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKSRPD 141
Query: 59 EGTYTCEASNCLGKAKS-NACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKC 117
EG Y C A N LG+A S NA L V R F P + +V GE +C
Sbjct: 142 EGVYVCVARNYLGEAVSHNASLEVAILR----------DDFRQNPSDVMVAVGEPAVMEC 191
Query: 118 -AVKGNPSPWASWDKDGS-IITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENEL 175
+G+P P SW KDGS + RIT++ + L I D G Y N +
Sbjct: 192 QPPRGHPEPTISWKKDGSPLDDKDERITIRGGK-----LMITYTRKSDAGKYVCVGTNMV 246
Query: 176 GRAEAS-ARLEVITR 189
G E+ A L V+ R
Sbjct: 247 GERESEVAELTVLER 261
Score = 37.9 bits (84), Expect = 0.027
Identities = 27/98 (27%), Positives = 40/98 (40%), Gaps = 7/98 (7%)
Query: 96 PTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITP------SARITVKEKEE 149
P +P + +V +GE T C +G P+P W K G + S R+ +
Sbjct: 68 PRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSL 127
Query: 150 IMRILEIDEVSIEDVGIYRITVENELGRAEA-SARLEV 186
+ S D G+Y N LG A + +A LEV
Sbjct: 128 FFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEV 165
>BC012102-1|AAH12102.1| 347|Homo sapiens PTPRF protein protein.
Length = 347
Score = 84.6 bits (200), Expect = 2e-16
Identities = 68/205 (33%), Positives = 89/205 (43%), Gaps = 13/205 (6%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTAR-LKIKQVTAE-DEGTYT 63
G F CQ TG P P I W + + +DDG L+I+ + + DE Y
Sbjct: 47 GGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYE 106
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
C A+N LG+ ++A L V +L PG P+ P KVVE+ T CA GNP
Sbjct: 107 CTATNSLGEINTSAKLSVLEEEQLP-PG---FPSIDMGPQLKVVEKARTATMLCAAGGNP 162
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG-RAEASA 182
P SW KD + P A + K+ L+I+ D G Y N G R A A
Sbjct: 163 DPEISWFKDFLPVDP-ATSNGRIKQLRSGALQIESSEESDQGKYECVATNSAGTRYSAPA 221
Query: 183 RLEVITRSGKFYGGLRAYSASPRKC 207
L V GK G A+ SP+ C
Sbjct: 222 NLYV---RGKDSGS--AWPLSPQSC 241
Score = 45.6 bits (103), Expect = 1e-04
Identities = 25/93 (26%), Positives = 40/93 (43%), Gaps = 1/93 (1%)
Query: 96 PTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILE 155
P F P ++ G +F C G P P +W K G ++ ++ + +L
Sbjct: 33 PVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLR 92
Query: 156 IDEVSIE-DVGIYRITVENELGRAEASARLEVI 187
I + ++ D IY T N LG SA+L V+
Sbjct: 93 IQPLRVQRDEAIYECTATNSLGEINTSAKLSVL 125
>AL583862-13|CAI14896.1| 347|Homo sapiens protein tyrosine
phosphatase, receptor type, F protein.
Length = 347
Score = 84.6 bits (200), Expect = 2e-16
Identities = 68/205 (33%), Positives = 89/205 (43%), Gaps = 13/205 (6%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTAR-LKIKQVTAE-DEGTYT 63
G F CQ TG P P I W + + +DDG L+I+ + + DE Y
Sbjct: 47 GGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYE 106
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
C A+N LG+ ++A L V +L PG P+ P KVVE+ T CA GNP
Sbjct: 107 CTATNSLGEINTSAKLSVLEEEQLP-PG---FPSIDMGPQLKVVEKARTATMLCAAGGNP 162
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG-RAEASA 182
P SW KD + P A + K+ L+I+ D G Y N G R A A
Sbjct: 163 DPEISWFKDFLPVDP-ATSNGRIKQLRSGALQIESSEESDQGKYECVATNSAGTRYSAPA 221
Query: 183 RLEVITRSGKFYGGLRAYSASPRKC 207
L V GK G A+ SP+ C
Sbjct: 222 NLYV---RGKDSGS--AWPLSPQSC 241
Score = 45.6 bits (103), Expect = 1e-04
Identities = 25/93 (26%), Positives = 40/93 (43%), Gaps = 1/93 (1%)
Query: 96 PTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILE 155
P F P ++ G +F C G P P +W K G ++ ++ + +L
Sbjct: 33 PVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLR 92
Query: 156 IDEVSIE-DVGIYRITVENELGRAEASARLEVI 187
I + ++ D IY T N LG SA+L V+
Sbjct: 93 IQPLRVQRDEAIYECTATNSLGEINTSAKLSVL 125
>BC013867-1|AAH13867.2| 510|Homo sapiens PALLD protein protein.
Length = 510
Score = 83.4 bits (197), Expect = 6e-16
Identities = 57/187 (30%), Positives = 88/187 (47%), Gaps = 8/187 (4%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIR-DCADFESSYDDGTARLKIKQVTAEDEGTYT 63
+G +C+V+G P PD+ W + +R D A ++G L I+ VT+ D G YT
Sbjct: 275 EGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYT 334
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
C A+N G+ + LVV ++ P F N V +G V +C V G P
Sbjct: 335 CIATNRAGQNSFSLELVV------AAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVP 388
Query: 124 SPWASWDKDGSIITPSA-RITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASA 182
P W K+ +T S R+++ + L I + ED G Y ++ +NE G +A
Sbjct: 389 PPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTA 448
Query: 183 RLEVITR 189
RL+V T+
Sbjct: 449 RLDVYTQ 455
Score = 75.4 bits (177), Expect = 1e-13
Identities = 63/215 (29%), Positives = 86/215 (40%), Gaps = 30/215 (13%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCAD-FESSYD-DGTARLKIKQVTAEDEGTY 62
+G V F C+V GNP P I WF + I +D + D DGT L T +D+G Y
Sbjct: 141 EGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNY 200
Query: 63 TCEASNCLGKAKSNACLVVY----------------HTRRLSSPGRQMA----------- 95
T A+N G+ L+V H RR S R
Sbjct: 201 TIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFF 260
Query: 96 -PTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRIL 154
P F P + V+EG+ C V G P+P SW DG + P + + +E + L
Sbjct: 261 RPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSL 320
Query: 155 EIDEVSIEDVGIYRITVENELGRAEASARLEVITR 189
I+ V+ D GIY N G+ S L V +
Sbjct: 321 IIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAK 355
Score = 53.2 bits (122), Expect = 7e-07
Identities = 34/94 (36%), Positives = 44/94 (46%), Gaps = 1/94 (1%)
Query: 94 MAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITP-SARITVKEKEEIMR 152
MAP F + + EG VTF C V GNP P W KDG I+P S T++ +
Sbjct: 126 MAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTC 185
Query: 153 ILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
L +++D G Y I N GR + RL V
Sbjct: 186 SLHTTASTLDDDGNYTIMAANPQGRISCTGRLMV 219
>AF151909-1|AAD34146.1| 404|Homo sapiens CGI-151 protein protein.
Length = 404
Score = 83.4 bits (197), Expect = 6e-16
Identities = 57/187 (30%), Positives = 88/187 (47%), Gaps = 8/187 (4%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIR-DCADFESSYDDGTARLKIKQVTAEDEGTYT 63
+G +C+V+G P PD+ W + +R D A ++G L I+ VT+ D G YT
Sbjct: 169 EGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYT 228
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
C A+N G+ + LVV ++ P F N V +G V +C V G P
Sbjct: 229 CIATNRAGQNSFSLELVV------AAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVP 282
Query: 124 SPWASWDKDGSIITPSA-RITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASA 182
P W K+ +T S R+++ + L I + ED G Y ++ +NE G +A
Sbjct: 283 PPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTA 342
Query: 183 RLEVITR 189
RL+V T+
Sbjct: 343 RLDVYTQ 349
Score = 75.4 bits (177), Expect = 1e-13
Identities = 63/215 (29%), Positives = 86/215 (40%), Gaps = 30/215 (13%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCAD-FESSYD-DGTARLKIKQVTAEDEGTY 62
+G V F C+V GNP P I WF + I +D + D DGT L T +D+G Y
Sbjct: 35 EGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNY 94
Query: 63 TCEASNCLGKAKSNACLVVY----------------HTRRLSSPGRQMA----------- 95
T A+N G+ L+V H RR S R
Sbjct: 95 TIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFF 154
Query: 96 -PTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRIL 154
P F P + V+EG+ C V G P+P SW DG + P + + +E + L
Sbjct: 155 RPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSL 214
Query: 155 EIDEVSIEDVGIYRITVENELGRAEASARLEVITR 189
I+ V+ D GIY N G+ S L V +
Sbjct: 215 IIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAK 249
Score = 53.2 bits (122), Expect = 7e-07
Identities = 34/94 (36%), Positives = 44/94 (46%), Gaps = 1/94 (1%)
Query: 94 MAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITP-SARITVKEKEEIMR 152
MAP F + + EG VTF C V GNP P W KDG I+P S T++ +
Sbjct: 20 MAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTC 79
Query: 153 ILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
L +++D G Y I N GR + RL V
Sbjct: 80 SLHTTASTLDDDGNYTIMAANPQGRISCTGRLMV 113
>AB023209-1|BAA76836.1| 772|Homo sapiens KIAA0992 protein protein.
Length = 772
Score = 83.4 bits (197), Expect = 6e-16
Identities = 57/187 (30%), Positives = 88/187 (47%), Gaps = 8/187 (4%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIR-DCADFESSYDDGTARLKIKQVTAEDEGTYT 63
+G +C+V+G P PD+ W + +R D A ++G L I+ VT+ D G YT
Sbjct: 537 EGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYT 596
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
C A+N G+ + LVV ++ P F N V +G V +C V G P
Sbjct: 597 CIATNRAGQNSFSLELVV------AAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVP 650
Query: 124 SPWASWDKDGSIITPSA-RITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASA 182
P W K+ +T S R+++ + L I + ED G Y ++ +NE G +A
Sbjct: 651 PPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTA 710
Query: 183 RLEVITR 189
RL+V T+
Sbjct: 711 RLDVYTQ 717
Score = 75.4 bits (177), Expect = 1e-13
Identities = 63/215 (29%), Positives = 86/215 (40%), Gaps = 30/215 (13%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCAD-FESSYD-DGTARLKIKQVTAEDEGTY 62
+G V F C+V GNP P I WF + I +D + D DGT L T +D+G Y
Sbjct: 403 EGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNY 462
Query: 63 TCEASNCLGKAKSNACLVVY----------------HTRRLSSPGRQMA----------- 95
T A+N G+ L+V H RR S R
Sbjct: 463 TIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFF 522
Query: 96 -PTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRIL 154
P F P + V+EG+ C V G P+P SW DG + P + + +E + L
Sbjct: 523 RPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSL 582
Query: 155 EIDEVSIEDVGIYRITVENELGRAEASARLEVITR 189
I+ V+ D GIY N G+ S L V +
Sbjct: 583 IIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAK 617
Score = 53.2 bits (122), Expect = 7e-07
Identities = 34/94 (36%), Positives = 44/94 (46%), Gaps = 1/94 (1%)
Query: 94 MAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITP-SARITVKEKEEIMR 152
MAP F + + EG VTF C V GNP P W KDG I+P S T++ +
Sbjct: 388 MAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTC 447
Query: 153 ILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
L +++D G Y I N GR + RL V
Sbjct: 448 SLHTTASTLDDDGNYTIMAANPQGRISCTGRLMV 481
>U72391-1|AAC51287.1| 1461|Homo sapiens neogenin protein.
Length = 1461
Score = 82.6 bits (195), Expect = 1e-15
Identities = 57/192 (29%), Positives = 85/192 (44%), Gaps = 16/192 (8%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G V C +G P P I+W E + D E L+I VT +D GTY C
Sbjct: 263 GQDVVLPCVASGLPTPTIKWMKNEEAL-DTESSERLVLLAGGSLEISDVTEDDAGTYFCI 321
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A N ++ A L V Q P F P N E ++ F+C V G P+P
Sbjct: 322 ADNGNETIEAQAELTV-----------QAQPEFLKQPTNIYAHESMDIVFECEVTGKPTP 370
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
W K+G ++ PS + KE +++L + + D G Y+ EN++G A+A A+L
Sbjct: 371 TVKWVKNGDMVIPSDYFKI-VKEHNLQVLGLVK---SDEGFYQCIAENDVGNAQAGAQLI 426
Query: 186 VITRSGKFYGGL 197
++ + G L
Sbjct: 427 ILEHAPATTGPL 438
Score = 38.3 bits (85), Expect = 0.021
Identities = 43/177 (24%), Positives = 67/177 (37%), Gaps = 19/177 (10%)
Query: 2 LSCDGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSY-DDGT---ARLKIKQVTAE 57
LS G +V C P P I W + +D DG+ + + +
Sbjct: 63 LSVRGSSVILNCSAYSEPSPKIEWKKDGTFLNLVSDDRRQLLPDGSLFISNVVHSKHNKP 122
Query: 58 DEGTYTCEAS-NCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFK 116
DEG Y C A+ LG ++ T +L G P F + P V G N
Sbjct: 123 DEGYYQCVATVESLGT-------IISRTAKLIVAG---LPRFTSQPEPSSVYAGNNAILN 172
Query: 117 CAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVEN 173
C V + P+ W+++ + R+ +K +L I + D G+YR VE+
Sbjct: 173 CEVNADLVPFVRWEQNRQPLLLDDRV-IKLPS---GMLVISNATEGDGGLYRCVVES 225
Score = 31.9 bits (69), Expect = 1.8
Identities = 16/52 (30%), Positives = 24/52 (46%), Gaps = 4/52 (7%)
Query: 89 SPG---RQMAPTFYTY-PFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSII 136
SPG R P ++ P + + G +V C+ PSP W KDG+ +
Sbjct: 42 SPGASIRTFTPFYFLVEPVDTLSVRGSSVILNCSAYSEPSPKIEWKKDGTFL 93
>U61262-1|AAB17263.1| 1461|Homo sapiens neogenin protein.
Length = 1461
Score = 82.6 bits (195), Expect = 1e-15
Identities = 57/192 (29%), Positives = 85/192 (44%), Gaps = 16/192 (8%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G V C +G P P I+W E + D E L+I VT +D GTY C
Sbjct: 263 GQDVVLPCVASGLPTPTIKWMKNEEAL-DTESSERLVLLAGGSLEISDVTEDDAGTYFCI 321
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A N ++ A L V Q P F P N E ++ F+C V G P+P
Sbjct: 322 ADNGNETIEAQAELTV-----------QAQPEFLKQPTNIYAHESMDIVFECEVTGKPTP 370
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
W K+G ++ PS + KE +++L + + D G Y+ EN++G A+A A+L
Sbjct: 371 TVKWVKNGDMVIPSDYFKI-VKEHNLQVLGLVK---SDEGFYQCIAENDVGNAQAGAQLI 426
Query: 186 VITRSGKFYGGL 197
++ + G L
Sbjct: 427 ILEHAPATTGPL 438
Score = 35.9 bits (79), Expect = 0.11
Identities = 43/179 (24%), Positives = 68/179 (37%), Gaps = 23/179 (12%)
Query: 2 LSCDGDTVEFECQVTGNPDPDIRWFH---YAEVIRDCADFESSYDDGT---ARLKIKQVT 55
LS G +V C P P I W + ++ D D DG+ + + +
Sbjct: 63 LSVRGSSVILNCSAYSEPSPKIEWKKDGTFLNLVSD--DRRQLLPDGSLFISNVVHSKHN 120
Query: 56 AEDEGTYTCEAS-NCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVT 114
DEG Y C A+ LG ++ T +L G P F + P V G
Sbjct: 121 KPDEGYYQCVATVESLG-------TIISRTAKLIVAG---LPRFTSQPEPSSVYAGNGAI 170
Query: 115 FKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVEN 173
C V + P+ W+++ + R+ +K +L I + D G+YR VE+
Sbjct: 171 LNCEVNADLVPFVRWEQNRQPLLLDDRV-IKLPS---GMLVISNATEGDGGLYRCVVES 225
Score = 31.9 bits (69), Expect = 1.8
Identities = 16/52 (30%), Positives = 24/52 (46%), Gaps = 4/52 (7%)
Query: 89 SPG---RQMAPTFYTY-PFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSII 136
SPG R P ++ P + + G +V C+ PSP W KDG+ +
Sbjct: 42 SPGASIRTFTPFYFLVEPVDTLSVRGSSVILNCSAYSEPSPKIEWKKDGTFL 93
>BC117161-1|AAI17162.1| 1461|Homo sapiens neogenin homolog 1
(chicken) protein.
Length = 1461
Score = 82.6 bits (195), Expect = 1e-15
Identities = 57/192 (29%), Positives = 85/192 (44%), Gaps = 16/192 (8%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G V C +G P P I+W E + D E L+I VT +D GTY C
Sbjct: 263 GQDVVLPCVASGLPTPTIKWMKNEEAL-DTESSERLVLLAGGSLEISDVTEDDAGTYFCI 321
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A N ++ A L V Q P F P N E ++ F+C V G P+P
Sbjct: 322 ADNGNETIEAQAELTV-----------QAQPEFLKQPTNIYAHESMDIVFECEVTGKPTP 370
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
W K+G ++ PS + KE +++L + + D G Y+ EN++G A+A A+L
Sbjct: 371 TVKWVKNGDMVIPSDYFKI-VKEHNLQVLGLVK---SDEGFYQCIAENDVGNAQAGAQLI 426
Query: 186 VITRSGKFYGGL 197
++ + G L
Sbjct: 427 ILEHAPATTGPL 438
Score = 38.3 bits (85), Expect = 0.021
Identities = 43/177 (24%), Positives = 67/177 (37%), Gaps = 19/177 (10%)
Query: 2 LSCDGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSY-DDGT---ARLKIKQVTAE 57
LS G +V C P P I W + +D DG+ + + +
Sbjct: 63 LSVRGSSVILNCSAYSEPSPKIEWKKDGTFLNLVSDDRRQLLPDGSLFISNVVHSKHNKP 122
Query: 58 DEGTYTCEAS-NCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFK 116
DEG Y C A+ LG ++ T +L G P F + P V G N
Sbjct: 123 DEGYYQCVATVESLGT-------IISRTAKLIVAG---LPRFTSQPEPSSVYAGNNAILN 172
Query: 117 CAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVEN 173
C V + P+ W+++ + R+ +K +L I + D G+YR VE+
Sbjct: 173 CEVNADLVPFVRWEQNRQPLLLDDRV-IKLPS---GMLVISNATEGDGGLYRCVVES 225
Score = 31.9 bits (69), Expect = 1.8
Identities = 16/52 (30%), Positives = 24/52 (46%), Gaps = 4/52 (7%)
Query: 89 SPG---RQMAPTFYTY-PFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSII 136
SPG R P ++ P + + G +V C+ PSP W KDG+ +
Sbjct: 42 SPGASIRTFTPFYFLVEPVDTLSVRGSSVILNCSAYSEPSPKIEWKKDGTFL 93
>Y00815-1|CAA68754.1| 1897|Homo sapiens put. LAR preprotein (AA -16
to 1881) protein.
Length = 1897
Score = 82.2 bits (194), Expect = 1e-15
Identities = 62/187 (33%), Positives = 81/187 (43%), Gaps = 8/187 (4%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTAR-LKIKQVTAE-DEGTYT 63
G F CQ TG P P I W + + +DDG L+I+ + + DE Y
Sbjct: 37 GGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYE 96
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
C A+N LG+ ++A L V +L PG P+ P KVVE+ T CA GNP
Sbjct: 97 CTATNSLGEINTSAKLSVLEEEQLP-PG---FPSIDMGPQLKVVEKARTATMLCAAGGNP 152
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG-RAEASA 182
P SW KD + P A + K+ L+I+ D G Y N G R A A
Sbjct: 153 DPEISWFKDFLPVDP-ATSNGRIKQLRSGALQIESSEESDQGKYECVATNSAGTRYSAPA 211
Query: 183 RLEVITR 189
L V R
Sbjct: 212 NLYVRVR 218
Score = 56.8 bits (131), Expect = 6e-08
Identities = 46/179 (25%), Positives = 68/179 (37%), Gaps = 14/179 (7%)
Query: 8 TVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEAS 67
T C GNPDP+I WF + + L+I+ D+G Y C A+
Sbjct: 141 TATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLRSGALQIESSEESDQGKYECVAT 200
Query: 68 NCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWA 127
N G S + RR+ AP F P ++ V G +V C G P P+
Sbjct: 201 NSAGTRYSAPANLYVRVRRV-------APRFSIPPSSQEVMPGGSVNLTCVAVGAPMPYV 253
Query: 128 SWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W +T + V +LE+ V + Y + LG EA+A++ V
Sbjct: 254 KWMMGAEELTKEDEMPVGR-----NVLELSNV-VRSAN-YTCVAISSLGMIEATAQVTV 305
Score = 45.6 bits (103), Expect = 1e-04
Identities = 25/93 (26%), Positives = 40/93 (43%), Gaps = 1/93 (1%)
Query: 96 PTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILE 155
P F P ++ G +F C G P P +W K G ++ ++ + +L
Sbjct: 23 PVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLR 82
Query: 156 IDEVSIE-DVGIYRITVENELGRAEASARLEVI 187
I + ++ D IY T N LG SA+L V+
Sbjct: 83 IQPLRVQRDEAIYECTATNSLGEINTSAKLSVL 115
Score = 29.5 bits (63), Expect = 9.6
Identities = 21/76 (27%), Positives = 31/76 (40%), Gaps = 6/76 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G +V C G P P ++W AE + E G L++ V YTC
Sbjct: 236 GGSVNLTCVAVGAPMPYVKWMMGAEELTK----EDEMPVGRNVLELSNVVR--SANYTCV 289
Query: 66 ASNCLGKAKSNACLVV 81
A + LG ++ A + V
Sbjct: 290 AISSLGMIEATAQVTV 305
>BC048768-1|AAH48768.1| 1898|Homo sapiens protein tyrosine
phosphatase, receptor type, F protein.
Length = 1898
Score = 82.2 bits (194), Expect = 1e-15
Identities = 62/187 (33%), Positives = 81/187 (43%), Gaps = 8/187 (4%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTAR-LKIKQVTAE-DEGTYT 63
G F CQ TG P P I W + + +DDG L+I+ + + DE Y
Sbjct: 47 GGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYE 106
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
C A+N LG+ ++A L V +L PG P+ P KVVE+ T CA GNP
Sbjct: 107 CTATNSLGEINTSAKLSVLEEEQLP-PG---FPSIDMGPQLKVVEKARTATMLCAAGGNP 162
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG-RAEASA 182
P SW KD + P A + K+ L+I+ D G Y N G R A A
Sbjct: 163 DPEISWFKDFLPVDP-ATSNGRIKQLRSGALQIESSEESDQGKYECVATNSAGTRYSAPA 221
Query: 183 RLEVITR 189
L V R
Sbjct: 222 NLYVRVR 228
Score = 56.8 bits (131), Expect = 6e-08
Identities = 46/179 (25%), Positives = 68/179 (37%), Gaps = 14/179 (7%)
Query: 8 TVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEAS 67
T C GNPDP+I WF + + L+I+ D+G Y C A+
Sbjct: 151 TATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLRSGALQIESSEESDQGKYECVAT 210
Query: 68 NCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWA 127
N G S + RR+ AP F P ++ V G +V C G P P+
Sbjct: 211 NSAGTRYSAPANLYVRVRRV-------APRFSIPPSSQEVMPGGSVNLTCVAVGAPMPYV 263
Query: 128 SWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W +T + V +LE+ V + Y + LG EA+A++ V
Sbjct: 264 KWMMGAEELTKEDEMPVGR-----NVLELSNV-VRSAN-YTCVAISSLGMIEATAQVTV 315
Score = 45.6 bits (103), Expect = 1e-04
Identities = 25/93 (26%), Positives = 40/93 (43%), Gaps = 1/93 (1%)
Query: 96 PTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILE 155
P F P ++ G +F C G P P +W K G ++ ++ + +L
Sbjct: 33 PVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLR 92
Query: 156 IDEVSIE-DVGIYRITVENELGRAEASARLEVI 187
I + ++ D IY T N LG SA+L V+
Sbjct: 93 IQPLRVQRDEAIYECTATNSLGEINTSAKLSVL 125
Score = 29.5 bits (63), Expect = 9.6
Identities = 21/76 (27%), Positives = 31/76 (40%), Gaps = 6/76 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G +V C G P P ++W AE + E G L++ V YTC
Sbjct: 246 GGSVNLTCVAVGAPMPYVKWMMGAEELTK----EDEMPVGRNVLELSNVVR--SANYTCV 299
Query: 66 ASNCLGKAKSNACLVV 81
A + LG ++ A + V
Sbjct: 300 AISSLGMIEATAQVTV 315
>BC048416-1|AAH48416.1| 353|Homo sapiens PTPRF protein protein.
Length = 353
Score = 82.2 bits (194), Expect = 1e-15
Identities = 68/210 (32%), Positives = 91/210 (43%), Gaps = 17/210 (8%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTAR-LKIKQVTAE-DEGTYT 63
G F CQ TG P P I W + + +DDG L+I+ + + DE Y
Sbjct: 47 GGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYE 106
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
C A+N LG+ ++A L V +L PG P+ P KVVE+ T CA GNP
Sbjct: 107 CTATNSLGEINTSAKLSVLEEEQLP-PG---FPSIDMGPQLKVVEKARTATMLCAAGGNP 162
Query: 124 SPWASWDKDGSIITP-SARITVKEKEE----IMRILEIDEVSIEDVGIYRITVENELG-R 177
P SW KD + P ++ +K+ I L+I+ D G Y N G R
Sbjct: 163 DPEISWFKDFLPVDPATSNGRIKQLRSGGSPIRGALQIESSEESDQGKYECVATNSAGTR 222
Query: 178 AEASARLEVITRSGKFYGGLRAYSASPRKC 207
A A L V GK G A+ SP+ C
Sbjct: 223 YSAPANLYV---RGKDSGS--AWPLSPQSC 247
Score = 45.6 bits (103), Expect = 1e-04
Identities = 25/93 (26%), Positives = 40/93 (43%), Gaps = 1/93 (1%)
Query: 96 PTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILE 155
P F P ++ G +F C G P P +W K G ++ ++ + +L
Sbjct: 33 PVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLR 92
Query: 156 IDEVSIE-DVGIYRITVENELGRAEASARLEVI 187
I + ++ D IY T N LG SA+L V+
Sbjct: 93 IQPLRVQRDEAIYECTATNSLGEINTSAKLSVL 125
>AL583862-12|CAI14897.1| 353|Homo sapiens protein tyrosine
phosphatase, receptor type, F protein.
Length = 353
Score = 82.2 bits (194), Expect = 1e-15
Identities = 68/210 (32%), Positives = 91/210 (43%), Gaps = 17/210 (8%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTAR-LKIKQVTAE-DEGTYT 63
G F CQ TG P P I W + + +DDG L+I+ + + DE Y
Sbjct: 47 GGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYE 106
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
C A+N LG+ ++A L V +L PG P+ P KVVE+ T CA GNP
Sbjct: 107 CTATNSLGEINTSAKLSVLEEEQLP-PG---FPSIDMGPQLKVVEKARTATMLCAAGGNP 162
Query: 124 SPWASWDKDGSIITP-SARITVKEKEE----IMRILEIDEVSIEDVGIYRITVENELG-R 177
P SW KD + P ++ +K+ I L+I+ D G Y N G R
Sbjct: 163 DPEISWFKDFLPVDPATSNGRIKQLRSGGSPIRGALQIESSEESDQGKYECVATNSAGTR 222
Query: 178 AEASARLEVITRSGKFYGGLRAYSASPRKC 207
A A L V GK G A+ SP+ C
Sbjct: 223 YSAPANLYV---RGKDSGS--AWPLSPQSC 247
Score = 45.6 bits (103), Expect = 1e-04
Identities = 25/93 (26%), Positives = 40/93 (43%), Gaps = 1/93 (1%)
Query: 96 PTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILE 155
P F P ++ G +F C G P P +W K G ++ ++ + +L
Sbjct: 33 PVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLR 92
Query: 156 IDEVSIE-DVGIYRITVENELGRAEASARLEVI 187
I + ++ D IY T N LG SA+L V+
Sbjct: 93 IQPLRVQRDEAIYECTATNSLGEINTSAKLSVL 125
>AL583862-10|CAI14894.1| 1907|Homo sapiens protein tyrosine
phosphatase, receptor type, F protein.
Length = 1907
Score = 82.2 bits (194), Expect = 1e-15
Identities = 62/187 (33%), Positives = 81/187 (43%), Gaps = 8/187 (4%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTAR-LKIKQVTAE-DEGTYT 63
G F CQ TG P P I W + + +DDG L+I+ + + DE Y
Sbjct: 47 GGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYE 106
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
C A+N LG+ ++A L V +L PG P+ P KVVE+ T CA GNP
Sbjct: 107 CTATNSLGEINTSAKLSVLEEEQLP-PG---FPSIDMGPQLKVVEKARTATMLCAAGGNP 162
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG-RAEASA 182
P SW KD + P A + K+ L+I+ D G Y N G R A A
Sbjct: 163 DPEISWFKDFLPVDP-ATSNGRIKQLRSGALQIESSEESDQGKYECVATNSAGTRYSAPA 221
Query: 183 RLEVITR 189
L V R
Sbjct: 222 NLYVRVR 228
Score = 56.8 bits (131), Expect = 6e-08
Identities = 46/179 (25%), Positives = 68/179 (37%), Gaps = 14/179 (7%)
Query: 8 TVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEAS 67
T C GNPDP+I WF + + L+I+ D+G Y C A+
Sbjct: 151 TATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLRSGALQIESSEESDQGKYECVAT 210
Query: 68 NCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWA 127
N G S + RR+ AP F P ++ V G +V C G P P+
Sbjct: 211 NSAGTRYSAPANLYVRVRRV-------APRFSIPPSSQEVMPGGSVNLTCVAVGAPMPYV 263
Query: 128 SWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W +T + V +LE+ V + Y + LG EA+A++ V
Sbjct: 264 KWMMGAEELTKEDEMPVGR-----NVLELSNV-VRSAN-YTCVAISSLGMIEATAQVTV 315
Score = 45.6 bits (103), Expect = 1e-04
Identities = 25/93 (26%), Positives = 40/93 (43%), Gaps = 1/93 (1%)
Query: 96 PTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILE 155
P F P ++ G +F C G P P +W K G ++ ++ + +L
Sbjct: 33 PVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLR 92
Query: 156 IDEVSIE-DVGIYRITVENELGRAEASARLEVI 187
I + ++ D IY T N LG SA+L V+
Sbjct: 93 IQPLRVQRDEAIYECTATNSLGEINTSAKLSVL 125
Score = 29.5 bits (63), Expect = 9.6
Identities = 21/76 (27%), Positives = 31/76 (40%), Gaps = 6/76 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G +V C G P P ++W AE + E G L++ V YTC
Sbjct: 246 GGSVNLTCVAVGAPMPYVKWMMGAEELTK----EDEMPVGRNVLELSNVVR--SANYTCV 299
Query: 66 ASNCLGKAKSNACLVV 81
A + LG ++ A + V
Sbjct: 300 AISSLGMIEATAQVTV 315
>AL583862-9|CAI14895.1| 1898|Homo sapiens protein tyrosine
phosphatase, receptor type, F protein.
Length = 1898
Score = 82.2 bits (194), Expect = 1e-15
Identities = 62/187 (33%), Positives = 81/187 (43%), Gaps = 8/187 (4%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTAR-LKIKQVTAE-DEGTYT 63
G F CQ TG P P I W + + +DDG L+I+ + + DE Y
Sbjct: 47 GGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYE 106
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
C A+N LG+ ++A L V +L PG P+ P KVVE+ T CA GNP
Sbjct: 107 CTATNSLGEINTSAKLSVLEEEQLP-PG---FPSIDMGPQLKVVEKARTATMLCAAGGNP 162
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG-RAEASA 182
P SW KD + P A + K+ L+I+ D G Y N G R A A
Sbjct: 163 DPEISWFKDFLPVDP-ATSNGRIKQLRSGALQIESSEESDQGKYECVATNSAGTRYSAPA 221
Query: 183 RLEVITR 189
L V R
Sbjct: 222 NLYVRVR 228
Score = 56.8 bits (131), Expect = 6e-08
Identities = 46/179 (25%), Positives = 68/179 (37%), Gaps = 14/179 (7%)
Query: 8 TVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEAS 67
T C GNPDP+I WF + + L+I+ D+G Y C A+
Sbjct: 151 TATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLRSGALQIESSEESDQGKYECVAT 210
Query: 68 NCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWA 127
N G S + RR+ AP F P ++ V G +V C G P P+
Sbjct: 211 NSAGTRYSAPANLYVRVRRV-------APRFSIPPSSQEVMPGGSVNLTCVAVGAPMPYV 263
Query: 128 SWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W +T + V +LE+ V + Y + LG EA+A++ V
Sbjct: 264 KWMMGAEELTKEDEMPVGR-----NVLELSNV-VRSAN-YTCVAISSLGMIEATAQVTV 315
Score = 45.6 bits (103), Expect = 1e-04
Identities = 25/93 (26%), Positives = 40/93 (43%), Gaps = 1/93 (1%)
Query: 96 PTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILE 155
P F P ++ G +F C G P P +W K G ++ ++ + +L
Sbjct: 33 PVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLR 92
Query: 156 IDEVSIE-DVGIYRITVENELGRAEASARLEVI 187
I + ++ D IY T N LG SA+L V+
Sbjct: 93 IQPLRVQRDEAIYECTATNSLGEINTSAKLSVL 125
Score = 29.5 bits (63), Expect = 9.6
Identities = 21/76 (27%), Positives = 31/76 (40%), Gaps = 6/76 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G +V C G P P ++W AE + E G L++ V YTC
Sbjct: 246 GGSVNLTCVAVGAPMPYVKWMMGAEELTK----EDEMPVGRNVLELSNVVR--SANYTCV 299
Query: 66 ASNCLGKAKSNACLVV 81
A + LG ++ A + V
Sbjct: 300 AISSLGMIEATAQVTV 315
>AB177857-1|BAD66835.1| 1918|Homo sapiens LAR protein.
Length = 1918
Score = 82.2 bits (194), Expect = 1e-15
Identities = 62/187 (33%), Positives = 81/187 (43%), Gaps = 8/187 (4%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTAR-LKIKQVTAE-DEGTYT 63
G F CQ TG P P I W + + +DDG L+I+ + + DE Y
Sbjct: 67 GGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYE 126
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
C A+N LG+ ++A L V +L PG P+ P KVVE+ T CA GNP
Sbjct: 127 CTATNSLGEINTSAKLSVLEEEQLP-PG---FPSIDMGPQLKVVEKARTATMLCAAGGNP 182
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG-RAEASA 182
P SW KD + P A + K+ L+I+ D G Y N G R A A
Sbjct: 183 DPEISWFKDFLPVDP-ATSNGRIKQLRSGALQIESSEESDQGKYECVATNSAGTRYSAPA 241
Query: 183 RLEVITR 189
L V R
Sbjct: 242 NLYVRVR 248
Score = 56.8 bits (131), Expect = 6e-08
Identities = 46/179 (25%), Positives = 68/179 (37%), Gaps = 14/179 (7%)
Query: 8 TVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEAS 67
T C GNPDP+I WF + + L+I+ D+G Y C A+
Sbjct: 171 TATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLRSGALQIESSEESDQGKYECVAT 230
Query: 68 NCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWA 127
N G S + RR+ AP F P ++ V G +V C G P P+
Sbjct: 231 NSAGTRYSAPANLYVRVRRV-------APRFSIPPSSQEVMPGGSVNLTCVAVGAPMPYV 283
Query: 128 SWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W +T + V +LE+ V + Y + LG EA+A++ V
Sbjct: 284 KWMMGAEELTKEDEMPVGR-----NVLELSNV-VRSAN-YTCVAISSLGMIEATAQVTV 335
Score = 45.6 bits (103), Expect = 1e-04
Identities = 25/93 (26%), Positives = 40/93 (43%), Gaps = 1/93 (1%)
Query: 96 PTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILE 155
P F P ++ G +F C G P P +W K G ++ ++ + +L
Sbjct: 53 PVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLR 112
Query: 156 IDEVSIE-DVGIYRITVENELGRAEASARLEVI 187
I + ++ D IY T N LG SA+L V+
Sbjct: 113 IQPLRVQRDEAIYECTATNSLGEINTSAKLSVL 145
Score = 29.5 bits (63), Expect = 9.6
Identities = 21/76 (27%), Positives = 31/76 (40%), Gaps = 6/76 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G +V C G P P ++W AE + E G L++ V YTC
Sbjct: 266 GGSVNLTCVAVGAPMPYVKWMMGAEELTK----EDEMPVGRNVLELSNVVR--SANYTCV 319
Query: 66 ASNCLGKAKSNACLVV 81
A + LG ++ A + V
Sbjct: 320 AISSLGMIEATAQVTV 335
>AB177856-1|BAD66834.1| 1484|Homo sapiens LAR splice variant 1
protein.
Length = 1484
Score = 82.2 bits (194), Expect = 1e-15
Identities = 62/187 (33%), Positives = 81/187 (43%), Gaps = 8/187 (4%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTAR-LKIKQVTAE-DEGTYT 63
G F CQ TG P P I W + + +DDG L+I+ + + DE Y
Sbjct: 67 GGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYE 126
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
C A+N LG+ ++A L V +L PG P+ P KVVE+ T CA GNP
Sbjct: 127 CTATNSLGEINTSAKLSVLEEEQLP-PG---FPSIDMGPQLKVVEKARTATMLCAAGGNP 182
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG-RAEASA 182
P SW KD + P A + K+ L+I+ D G Y N G R A A
Sbjct: 183 DPEISWFKDFLPVDP-ATSNGRIKQLRSGALQIESSEESDQGKYECVATNSAGTRYSAPA 241
Query: 183 RLEVITR 189
L V R
Sbjct: 242 NLYVRVR 248
Score = 45.6 bits (103), Expect = 1e-04
Identities = 25/93 (26%), Positives = 40/93 (43%), Gaps = 1/93 (1%)
Query: 96 PTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILE 155
P F P ++ G +F C G P P +W K G ++ ++ + +L
Sbjct: 53 PVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLR 112
Query: 156 IDEVSIE-DVGIYRITVENELGRAEASARLEVI 187
I + ++ D IY T N LG SA+L V+
Sbjct: 113 IQPLRVQRDEAIYECTATNSLGEINTSAKLSVL 145
Score = 38.7 bits (86), Expect = 0.016
Identities = 22/81 (27%), Positives = 32/81 (39%)
Query: 8 TVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEAS 67
T C GNPDP+I WF + + L+I+ D+G Y C A+
Sbjct: 171 TATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLRSGALQIESSEESDQGKYECVAT 230
Query: 68 NCLGKAKSNACLVVYHTRRLS 88
N G S + RR++
Sbjct: 231 NSAGTRYSAPANLYVRVRRVA 251
>AK056544-1|BAB71212.1| 1034|Homo sapiens protein ( Homo sapiens
cDNA FLJ31982 fis, clone NT2RP7008550, highly similar to
Mus musculus rig-1 protein mRNA. ).
Length = 1034
Score = 81.8 bits (193), Expect = 2e-15
Identities = 60/182 (32%), Positives = 85/182 (46%), Gaps = 19/182 (10%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
V F C+V G+P P +RW + +E D L I V+AEDEGTYTC A N
Sbjct: 275 VTFLCEVKGDPPPRLRW-RKEDGELPTGRYEIRSDHS---LWIGHVSAEDEGTYTCVAEN 330
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
+G+A+++ L V+ + P T P +++ GE+V F+C KGNP P
Sbjct: 331 SVGRAEASGSLSVH-----------VPPQLVTQPQDQMAAPGESVAFQCETKGNPPPAIF 379
Query: 129 WDKDGS--IITPSARI--TVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
W K+GS ++ PS + T + L I V D G Y + G A A L
Sbjct: 380 WQKEGSQVLLFPSQSLQPTGRFSVSPRGQLNITAVQRGDAGYYMCQAVSVAGSILAKALL 439
Query: 185 EV 186
E+
Sbjct: 440 EI 441
Score = 78.6 bits (185), Expect = 2e-14
Identities = 60/183 (32%), Positives = 80/183 (43%), Gaps = 21/183 (11%)
Query: 6 GDTVEFEC-QVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
G+ EC G+P+P + W +++ E +L + D G Y C
Sbjct: 180 GEPAVLECVPPRGHPEPSVSWRKDGARLKE---EEGRITIRGGKLMMSHTLKSDAGMYVC 236
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
ASN G+ +S A V+ R P+F P N+VV VTF C VKG+P
Sbjct: 237 VASNMAGERESAAAEVMVLER----------PSFLRRPVNQVVLADAPVTFLCEVKGDPP 286
Query: 125 PWASWDK-DGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
P W K DG + P+ R ++ L I VS ED G Y EN +GRAEAS
Sbjct: 287 PRLRWRKEDGEL--PTGRYEIRSDHS----LWIGHVSAEDEGTYTCVAENSVGRAEASGS 340
Query: 184 LEV 186
L V
Sbjct: 341 LSV 343
Score = 60.9 bits (141), Expect = 3e-09
Identities = 51/193 (26%), Positives = 79/193 (40%), Gaps = 19/193 (9%)
Query: 2 LSCDGDTVEFECQVTGNPDPDIRW--------FHYAEVIRDCADFESSYDDGTARLKIKQ 53
++ G++V F+C+ GNP P I W ++ ++ F S +L I
Sbjct: 357 MAAPGESVAFQCETKGNPPPAIFWQKEGSQVLLFPSQSLQPTGRFSVS---PRGQLNITA 413
Query: 54 VTAEDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENV 113
V D G Y C+A + G + A L + + S G + P P N+ + G +V
Sbjct: 414 VQRGDAGYYMCQAVSVAGSILAKALLEI---KGASLDG--LPPVILQGPANQTLVLGSSV 468
Query: 114 TFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVEN 173
C V GNP P W KDG + ++ K L I V D+G Y ++
Sbjct: 469 WLPCRVTGNPQPSVRWKKDGQWLQGD---DLQFKTMANGTLYIANVQEMDMGFYSCVAKS 525
Query: 174 ELGRAEASARLEV 186
G A S L++
Sbjct: 526 STGEATWSGWLKM 538
Score = 58.8 bits (136), Expect = 1e-08
Identities = 60/200 (30%), Positives = 80/200 (40%), Gaps = 26/200 (13%)
Query: 1 MLSCDGDTVEFECQVTGNPDPDIRWF----HYAEVIRDCADFESSYDDGTA---RLKIKQ 53
+L G+ C+ G P P+I W+ A V D G R+ +
Sbjct: 73 LLVSRGEPATLPCRAEGRPRPNIEWYKNGARVATVREDPRAHRLLLPSGALFFPRIVHGR 132
Query: 54 VTAEDEGTYTCEASNCLGKAKS-NACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGEN 112
DEG YTC A N LG A S NA L V R F P N VV GE
Sbjct: 133 RARPDEGVYTCVARNYLGAAASRNASLEVAVLR----------DDFRQSPGNVVVAVGEP 182
Query: 113 VTFKCA-VKGNPSPWASWDKDGS-IITPSARITVKEKEEIMRILEIDEVSIEDVGIYRIT 170
+C +G+P P SW KDG+ + RIT++ + L + D G+Y
Sbjct: 183 AVLECVPPRGHPEPSVSWRKDGARLKEEEGRITIRGGK-----LMMSHTLKSDAGMYVCV 237
Query: 171 VENELG-RAEASARLEVITR 189
N G R A+A + V+ R
Sbjct: 238 ASNMAGERESAAAEVMVLER 257
Score = 33.5 bits (73), Expect = 0.59
Identities = 27/98 (27%), Positives = 40/98 (40%), Gaps = 7/98 (7%)
Query: 96 PTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIIT-----PSA-RITVKEKEE 149
P P + +V GE T C +G P P W K+G+ + P A R+ +
Sbjct: 64 PRIVEQPPDLLVSRGEPATLPCRAEGRPRPNIEWYKNGARVATVREDPRAHRLLLPSGAL 123
Query: 150 IMRILEIDEVSIEDVGIYRITVENELGRAEA-SARLEV 186
+ + D G+Y N LG A + +A LEV
Sbjct: 124 FFPRIVHGRRARPDEGVYTCVARNYLGAAASRNASLEV 161
>BC107797-1|AAI07798.1| 179|Homo sapiens TTN protein protein.
Length = 179
Score = 81.4 bits (192), Expect = 2e-15
Identities = 47/184 (25%), Positives = 86/184 (46%), Gaps = 13/184 (7%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G V F C+++G P P+I WF I ++ S L+I+ + D G YT
Sbjct: 4 EGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTI 63
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
+A N G+ + A L+V ++ P P + ++EG+ +T CA G P+
Sbjct: 64 KAKNFRGQCSATASLMVL----------RIPPKIEALPSDISIDEGKVLTVACAFTGEPT 113
Query: 125 PWASWDKDGSII--TPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASA 182
P +W G I R ++ +++ ++ +D V +D G+Y +++ NE G A+
Sbjct: 114 PEVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMD-VQKQDGGLYTLSLGNEFGSDSATV 172
Query: 183 RLEV 186
+ +
Sbjct: 173 NIHI 176
Score = 57.6 bits (133), Expect = 3e-08
Identities = 28/81 (34%), Positives = 43/81 (53%), Gaps = 1/81 (1%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
+ EG+NV F C + G PSP W K+ I+ S+ +++ + LEI S+ D G
Sbjct: 2 INEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYS-LEIRNASVSDSGK 60
Query: 167 YRITVENELGRAEASARLEVI 187
Y I +N G+ A+A L V+
Sbjct: 61 YTIKAKNFRGQCSATASLMVL 81
>AL583862-11|CAM12884.1| 262|Homo sapiens protein tyrosine
phosphatase, receptor type, F protein.
Length = 262
Score = 81.4 bits (192), Expect = 2e-15
Identities = 61/184 (33%), Positives = 80/184 (43%), Gaps = 8/184 (4%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTAR-LKIKQVTAE-DEGTYT 63
G F CQ TG P P I W + + +DDG L+I+ + + DE Y
Sbjct: 47 GGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYE 106
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
C A+N LG+ ++A L V +L PG P+ P KVVE+ T CA GNP
Sbjct: 107 CTATNSLGEINTSAKLSVLEEEQLP-PG---FPSIDMGPQLKVVEKARTATMLCAAGGNP 162
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG-RAEASA 182
P SW KD + P A + K+ L+I+ D G Y N G R A A
Sbjct: 163 DPEISWFKDFLPVDP-ATSNGRIKQLRSGALQIESSEESDQGKYECVATNSAGTRYSAPA 221
Query: 183 RLEV 186
L V
Sbjct: 222 NLYV 225
Score = 45.6 bits (103), Expect = 1e-04
Identities = 25/93 (26%), Positives = 40/93 (43%), Gaps = 1/93 (1%)
Query: 96 PTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILE 155
P F P ++ G +F C G P P +W K G ++ ++ + +L
Sbjct: 33 PVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLR 92
Query: 156 IDEVSIE-DVGIYRITVENELGRAEASARLEVI 187
I + ++ D IY T N LG SA+L V+
Sbjct: 93 IQPLRVQRDEAIYECTATNSLGEINTSAKLSVL 125
>AF464873-1|AAL69964.1| 1106|Homo sapiens myoneurin protein.
Length = 1106
Score = 81.4 bits (192), Expect = 2e-15
Identities = 56/184 (30%), Positives = 86/184 (46%), Gaps = 8/184 (4%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIR-DCADFESSYDDGTARLKIKQVTAEDEGTYT 63
+G +C+V+G P PD+ W + +R D A ++G L I+ VT+ D G YT
Sbjct: 924 EGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYT 983
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
C A+N G+ + LVV ++ P F N V +G V +C V G P
Sbjct: 984 CIATNRAGQNSFSLELVV------AAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVP 1037
Query: 124 SPWASWDKDGSIITPSA-RITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASA 182
P W K+ +T S R+++ + L I + ED G Y ++ +NE G +A
Sbjct: 1038 PPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTA 1097
Query: 183 RLEV 186
RL+V
Sbjct: 1098 RLDV 1101
Score = 75.4 bits (177), Expect = 1e-13
Identities = 63/215 (29%), Positives = 86/215 (40%), Gaps = 30/215 (13%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCAD-FESSYD-DGTARLKIKQVTAEDEGTY 62
+G V F C+V GNP P I WF + I +D + D DGT L T +D+G Y
Sbjct: 790 EGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNY 849
Query: 63 TCEASNCLGKAKSNACLVVY----------------HTRRLSSPGRQMA----------- 95
T A+N G+ L+V H RR S R
Sbjct: 850 TIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFF 909
Query: 96 -PTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRIL 154
P F P + V+EG+ C V G P+P SW DG + P + + +E + L
Sbjct: 910 RPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSL 969
Query: 155 EIDEVSIEDVGIYRITVENELGRAEASARLEVITR 189
I+ V+ D GIY N G+ S L V +
Sbjct: 970 IIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAK 1004
Score = 53.2 bits (122), Expect = 7e-07
Identities = 28/92 (30%), Positives = 44/92 (47%), Gaps = 1/92 (1%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTAR-LKIKQVTAEDEGTYT 63
+G V EC+VTGNP P +RWF + + + D + + G L I + +D G YT
Sbjct: 284 EGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGRYT 343
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMA 95
C A+N G ++A + + S +A
Sbjct: 344 CLATNPSGSDTTSAEVFIEGASSTDSDSESLA 375
Score = 53.2 bits (122), Expect = 7e-07
Identities = 34/94 (36%), Positives = 44/94 (46%), Gaps = 1/94 (1%)
Query: 94 MAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITP-SARITVKEKEEIMR 152
MAP F + + EG VTF C V GNP P W KDG I+P S T++ +
Sbjct: 775 MAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTC 834
Query: 153 ILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
L +++D G Y I N GR + RL V
Sbjct: 835 SLHTTASTLDDDGNYTIMAANPQGRISCTGRLMV 868
Score = 49.6 bits (113), Expect = 8e-06
Identities = 29/85 (34%), Positives = 39/85 (45%), Gaps = 8/85 (9%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADF--------ESSYDDGTARLKIKQVTA 56
+G V EC+V G P ++WF I+D DF ++ + L I +
Sbjct: 454 EGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAETFP 513
Query: 57 EDEGTYTCEASNCLGKAKSNACLVV 81
ED G +TC A N G A S A LVV
Sbjct: 514 EDAGIFTCSARNDYGSATSTAQLVV 538
Score = 48.0 bits (109), Expect = 3e-05
Identities = 35/99 (35%), Positives = 48/99 (48%), Gaps = 9/99 (9%)
Query: 96 PTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSII--TPSARITVK------EK 147
P F N V EG+ V +C V+G P W + GS I +P RI K E
Sbjct: 441 PVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEP 500
Query: 148 EEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
EEI ++ I E ED GI+ + N+ G A ++A+L V
Sbjct: 501 EEICTLV-IAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
Score = 47.6 bits (108), Expect = 3e-05
Identities = 32/83 (38%), Positives = 37/83 (44%), Gaps = 2/83 (2%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDD--GTARLKIKQVTAEDEGTY 62
DG V EC+V G P P I W E + D S + D G L I+ T ED G Y
Sbjct: 1023 DGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWY 1082
Query: 63 TCEASNCLGKAKSNACLVVYHTR 85
T A N G A L VY +R
Sbjct: 1083 TVSAKNEAGIVSCTARLDVYISR 1105
Score = 40.3 bits (90), Expect = 0.005
Identities = 26/90 (28%), Positives = 38/90 (42%)
Query: 95 APTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRIL 154
AP F ++ V EG V +C V GNP+P W +G + + I + + + L
Sbjct: 270 APRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTL 329
Query: 155 EIDEVSIEDVGIYRITVENELGRAEASARL 184
I E +D G Y N G SA +
Sbjct: 330 IIAEAFEDDTGRYTCLATNPSGSDTTSAEV 359
>AY509035-1|AAS91662.1| 1386|Homo sapiens roundabout-like protein 3
protein.
Length = 1386
Score = 81.0 bits (191), Expect = 3e-15
Identities = 60/182 (32%), Positives = 85/182 (46%), Gaps = 19/182 (10%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
V F C+V G+P P +RW + +E D L I V+AEDEGTYTC A N
Sbjct: 275 VTFLCEVKGDPPPRLRW-RKEDGELPTGRYEIRSDHS---LWIGHVSAEDEGTYTCVAEN 330
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
+G+A+++ L V+ + P T P +++ GE+V F+C KGNP P
Sbjct: 331 SVGRAEASGSLSVH-----------VPPQLVTQPQDQMAAPGESVAFQCETKGNPPPAIF 379
Query: 129 WDKDGS--IITPSARI--TVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
W K+GS ++ PS + T + L I V D G Y + G A A L
Sbjct: 380 WQKEGSQVLLFPSQSLQPTGRFSVSPRGQLNITAVQRGDAGYYVCQAVSVAGSILAKALL 439
Query: 185 EV 186
E+
Sbjct: 440 EI 441
Score = 78.6 bits (185), Expect = 2e-14
Identities = 60/183 (32%), Positives = 80/183 (43%), Gaps = 21/183 (11%)
Query: 6 GDTVEFEC-QVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
G+ EC G+P+P + W +++ E +L + D G Y C
Sbjct: 180 GEPAVLECVPPRGHPEPSVSWRKDGARLKE---EEGRITIRGGKLMMSHTLKSDAGMYVC 236
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
ASN G+ +S A V+ R P+F P N+VV VTF C VKG+P
Sbjct: 237 VASNMAGERESAAAEVMVLER----------PSFLRRPVNQVVLADAPVTFLCEVKGDPP 286
Query: 125 PWASWDK-DGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
P W K DG + P+ R ++ L I VS ED G Y EN +GRAEAS
Sbjct: 287 PRLRWRKEDGEL--PTGRYEIRSDHS----LWIGHVSAEDEGTYTCVAENSVGRAEASGS 340
Query: 184 LEV 186
L V
Sbjct: 341 LSV 343
Score = 61.3 bits (142), Expect = 3e-09
Identities = 51/193 (26%), Positives = 79/193 (40%), Gaps = 19/193 (9%)
Query: 2 LSCDGDTVEFECQVTGNPDPDIRW--------FHYAEVIRDCADFESSYDDGTARLKIKQ 53
++ G++V F+C+ GNP P I W ++ ++ F S +L I
Sbjct: 357 MAAPGESVAFQCETKGNPPPAIFWQKEGSQVLLFPSQSLQPTGRFSVS---PRGQLNITA 413
Query: 54 VTAEDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENV 113
V D G Y C+A + G + A L + + S G + P P N+ + G +V
Sbjct: 414 VQRGDAGYYVCQAVSVAGSILAKALLEI---KGASLDG--LPPVILQGPANQTLVLGSSV 468
Query: 114 TFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVEN 173
C V GNP P W KDG + ++ K L I V D+G Y ++
Sbjct: 469 WLPCRVTGNPQPSVRWKKDGQWLQGD---DLQFKTMANGTLYIANVQEMDMGFYSCVAKS 525
Query: 174 ELGRAEASARLEV 186
G A S L++
Sbjct: 526 STGEATWSGWLKM 538
Score = 58.8 bits (136), Expect = 1e-08
Identities = 60/200 (30%), Positives = 80/200 (40%), Gaps = 26/200 (13%)
Query: 1 MLSCDGDTVEFECQVTGNPDPDIRWF----HYAEVIRDCADFESSYDDGTA---RLKIKQ 53
+L G+ C+ G P P+I W+ A V D G R+ +
Sbjct: 73 LLVSRGEPATLPCRAEGRPRPNIEWYKNGARVATVREDPRAHRLLLPSGALFFPRIVHGR 132
Query: 54 VTAEDEGTYTCEASNCLGKAKS-NACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGEN 112
DEG YTC A N LG A S NA L V R F P N VV GE
Sbjct: 133 RARPDEGVYTCVARNYLGAAASRNASLEVAVLR----------DDFRQSPGNVVVAVGEP 182
Query: 113 VTFKCA-VKGNPSPWASWDKDGS-IITPSARITVKEKEEIMRILEIDEVSIEDVGIYRIT 170
+C +G+P P SW KDG+ + RIT++ + L + D G+Y
Sbjct: 183 AVLECVPPRGHPEPSVSWRKDGARLKEEEGRITIRGGK-----LMMSHTLKSDAGMYVCV 237
Query: 171 VENELG-RAEASARLEVITR 189
N G R A+A + V+ R
Sbjct: 238 ASNMAGERESAAAEVMVLER 257
Score = 33.5 bits (73), Expect = 0.59
Identities = 27/98 (27%), Positives = 40/98 (40%), Gaps = 7/98 (7%)
Query: 96 PTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIIT-----PSA-RITVKEKEE 149
P P + +V GE T C +G P P W K+G+ + P A R+ +
Sbjct: 64 PRIVEQPPDLLVSRGEPATLPCRAEGRPRPNIEWYKNGARVATVREDPRAHRLLLPSGAL 123
Query: 150 IMRILEIDEVSIEDVGIYRITVENELGRAEA-SARLEV 186
+ + D G+Y N LG A + +A LEV
Sbjct: 124 FFPRIVHGRRARPDEGVYTCVARNYLGAAASRNASLEV 161
>DQ234351-1|ABB29980.1| 262|Homo sapiens protein tyrosine
phosphatase receptor type F protein.
Length = 262
Score = 80.2 bits (189), Expect = 5e-15
Identities = 61/184 (33%), Positives = 79/184 (42%), Gaps = 8/184 (4%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTAR-LKIKQVTAE-DEGTYT 63
G F CQ TG P P I W + + +DDG L+I+ + + DE Y
Sbjct: 47 GGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYE 106
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
C A+N LG ++A L V +L PG P+ P KVVE+ T CA GNP
Sbjct: 107 CTATNSLGGINTSAKLSVLEEEQLP-PG---FPSIDMGPQLKVVEKARTATMLCAAGGNP 162
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG-RAEASA 182
P SW KD + P A + K+ L+I+ D G Y N G R A A
Sbjct: 163 DPEISWFKDFLPVDP-ATSNGRIKQLRSGALQIESSEESDQGKYECVATNSAGTRYSAPA 221
Query: 183 RLEV 186
L V
Sbjct: 222 NLYV 225
Score = 44.8 bits (101), Expect = 2e-04
Identities = 25/93 (26%), Positives = 40/93 (43%), Gaps = 1/93 (1%)
Query: 96 PTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILE 155
P F P ++ G +F C G P P +W K G ++ ++ + +L
Sbjct: 33 PVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLR 92
Query: 156 IDEVSIE-DVGIYRITVENELGRAEASARLEVI 187
I + ++ D IY T N LG SA+L V+
Sbjct: 93 IQPLRVQRDEAIYECTATNSLGGINTSAKLSVL 125
>X76132-1|CAA53735.1| 1447|Homo sapiens tumour suppressor protein.
Length = 1447
Score = 79.8 bits (188), Expect = 7e-15
Identities = 56/186 (30%), Positives = 84/186 (45%), Gaps = 17/186 (9%)
Query: 1 MLSCDGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEG 60
+++ +G EC V+G P P W EVI+ + S G + L I VT +D G
Sbjct: 249 VVAIEGKDAVLECCVSGYPPPSFTWLRGEEVIQLRSKKYSLL--GGSNLLISNVTDDDSG 306
Query: 61 TYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVK 120
YTC + ++A L V + P F +P N E ++ F+C V
Sbjct: 307 MYTCVVTYKNENISASAELTVL-----------VPPWFLNHPSNLYAYESMDIEFECTVS 355
Query: 121 GNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEA 180
G P P +W K+G ++ PS + +RIL + + D G Y+ ENE G A+
Sbjct: 356 GKPVPTVNWMKNGDVVIPSDYFQIVGGSN-LRILGVVK---SDEGFYQCVAENEAGNAQT 411
Query: 181 SARLEV 186
SA+L V
Sbjct: 412 SAQLIV 417
Score = 65.3 bits (152), Expect = 2e-10
Identities = 51/183 (27%), Positives = 75/183 (40%), Gaps = 9/183 (4%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
GDTV +C+V G P P I W + + + L+I ++ D G Y C
Sbjct: 154 GDTVLLKCEVIGEPMPTIHWQKNQQDLTPIPGDSRVVVLPSGALQISRLQPGDIGIYRCS 213
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A N N V R LS PG F P N V EG++ +C V G P P
Sbjct: 214 ARNPASSRTGNEAEV----RILSDPGLHRQLYFLQRPSNVVAIEGKDAVLECCVSGYPPP 269
Query: 126 WASWDKDGSII-TPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
+W + +I S + ++ ++ I V+ +D G+Y V + ASA L
Sbjct: 270 SFTWLRGEEVIQLRSKKYSLLGGSNLL----ISNVTDDDSGMYTCVVTYKNENISASAEL 325
Query: 185 EVI 187
V+
Sbjct: 326 TVL 328
Score = 45.2 bits (102), Expect = 2e-04
Identities = 39/138 (28%), Positives = 60/138 (43%), Gaps = 17/138 (12%)
Query: 58 DEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKC 117
DEG Y CEAS LG + S ++ T +++ G F + + G+ V KC
Sbjct: 111 DEGLYQCEAS--LGDSGS----IISRTAKVAVAG---PLRFLSQTESVTAFMGDTVLLKC 161
Query: 118 AVKGNPSPWASWDKDGSIITP---SARITVKEKEEIMRILEIDEVSIEDVGIYRITVENE 174
V G P P W K+ +TP +R+ V L+I + D+GIYR + N
Sbjct: 162 EVIGEPMPTIHWQKNQQDLTPIPGDSRVVVLPS----GALQISRLQPGDIGIYRCSARNP 217
Query: 175 L-GRAEASARLEVITRSG 191
R A + +++ G
Sbjct: 218 ASSRTGNEAEVRILSDPG 235
>X64697-1|CAA45938.1| 3100|Homo sapiens titin protein.
Length = 3100
Score = 79.8 bits (188), Expect = 7e-15
Identities = 51/172 (29%), Positives = 76/172 (44%), Gaps = 7/172 (4%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSY----DDGTARLKIKQVTAEDEGT 61
G+ V F +T +P+P + W+ + I+ D + Y D G +L I VT +D+
Sbjct: 2931 GENVRFGVTITVHPEPHVTWYKSGQKIKP-GDNDKKYTFESDKGLYQLTINSVTTDDDAE 2989
Query: 62 YTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKG 121
YT A N G+ A L V T + P F N +EG++V F+ V G
Sbjct: 2990 YTVVARNKYGEDSCKAKLTV--TLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSG 3047
Query: 122 NPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVEN 173
P P W+KDG ++ I + + L I + ED G YR+T N
Sbjct: 3048 IPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATN 3099
Score = 77.4 bits (182), Expect = 4e-14
Identities = 54/202 (26%), Positives = 91/202 (45%), Gaps = 20/202 (9%)
Query: 5 DGDTVEFECQVTG-NPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYT 63
+G V++ C++ + + W+ + + +E +Y+DG A L +K +T D+GTY
Sbjct: 2808 EGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYR 2867
Query: 64 CEASNCLGKAKSNACLVV--------YHTRRLSSPGRQMAPTF--------YTYP-FNKV 106
C+ N G+ S A L V Y+ RR ++ T +T P +NK
Sbjct: 2868 CKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNKT 2927
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITP--SARITVKEKEEIMRILEIDEVSIEDV 164
GENV F + +P P +W K G I P + + E ++ + L I+ V+ +D
Sbjct: 2928 AYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDD 2987
Query: 165 GIYRITVENELGRAEASARLEV 186
Y + N+ G A+L V
Sbjct: 2988 AEYTVVARNKYGEDSCKAKLTV 3009
Score = 76.6 bits (180), Expect = 6e-14
Identities = 44/187 (23%), Positives = 83/187 (44%), Gaps = 8/187 (4%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+ + CQ+ G P PDI+W+ + + + ++ S D T L + EDEG YTC
Sbjct: 1774 GEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCI 1833
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A+N +G+ ++++ L++ T + PG + +Y G + G P P
Sbjct: 1834 ATNEVGEVETSSKLLLQATPQF-HPGYPLKEKYYG-------AVGSTLRLHVMYIGRPVP 1885
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
+W ++ S IT++ E ++ + G Y++ + N G +A +E
Sbjct: 1886 AMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVE 1945
Query: 186 VITRSGK 192
+ + K
Sbjct: 1946 IQDKPDK 1952
Score = 58.8 bits (136), Expect = 1e-08
Identities = 43/176 (24%), Positives = 72/176 (40%), Gaps = 8/176 (4%)
Query: 13 CQVTGNPDPDIRWFHYA-EVIRDCADFE-SSYDDGTARLKIKQVTAEDEGTYTCEASNCL 70
C+VTG+P P ++W+ E+I D + + G +L I VT +D Y A+N
Sbjct: 2176 CKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQG 2235
Query: 71 GKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWD 130
G A L V ++ P + + + GE V+ K G P P +W
Sbjct: 2236 GSVSGTASLEVEVPAKIHLP-KTLEGMGAVHALR-----GEVVSIKIPFSGKPDPVITWQ 2289
Query: 131 KDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
K +I + V ++ + V +D G Y + +N G + + L+V
Sbjct: 2290 KGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDV 2345
Score = 45.2 bits (102), Expect = 2e-04
Identities = 26/92 (28%), Positives = 45/92 (48%), Gaps = 1/92 (1%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
V G V + G P P ASW GS + S R+TV+ ++ + L I E +I D G
Sbjct: 977 VPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAK-LTIRETTIRDTGE 1035
Query: 167 YRITVENELGRAEASARLEVITRSGKFYGGLR 198
Y + ++N G + ++ ++ + G G ++
Sbjct: 1036 YTLELKNVTGTTLETIKVIILDKPGPPTGPIK 1067
Score = 44.4 bits (100), Expect = 3e-04
Identities = 28/93 (30%), Positives = 41/93 (44%), Gaps = 1/93 (1%)
Query: 95 APTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDG-SIITPSARITVKEKEEIMRI 153
AP F N V N T C V G+P P W + G II + ++E +
Sbjct: 2154 APHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQ 2213
Query: 154 LEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
L I V+ +D +Y++ N+ G +A LEV
Sbjct: 2214 LIIASVTDDDATVYQVRATNQGGSVSGTASLEV 2246
Score = 42.3 bits (95), Expect = 0.001
Identities = 24/85 (28%), Positives = 39/85 (45%), Gaps = 3/85 (3%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
+ G ++ +V G P P +W K G + A I E + L +D+V+ D G
Sbjct: 685 IRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSL---LIVDKVNRYDAGK 741
Query: 167 YRITVENELGRAEASARLEVITRSG 191
Y I EN+ G+ A+ ++V G
Sbjct: 742 YTIEAENQSGKKSATVLVKVYDTPG 766
Score = 42.3 bits (95), Expect = 0.001
Identities = 24/81 (29%), Positives = 36/81 (44%), Gaps = 3/81 (3%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
V +G + +KG P P W K+G I+ A I E + I E D D G
Sbjct: 1375 VRQGGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETHTELVIKEADR---GDSGT 1431
Query: 167 YRITVENELGRAEASARLEVI 187
Y + +EN+ G+ ++ VI
Sbjct: 1432 YDLVLENKCGKKAVYIKVRVI 1452
Score = 40.3 bits (90), Expect = 0.005
Identities = 24/91 (26%), Positives = 33/91 (36%), Gaps = 5/91 (5%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G VE + G P P WF +R+ A+L I++ T D G YT E
Sbjct: 980 GRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLE 1039
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAP 96
N G +++ L PG P
Sbjct: 1040 LKNVTGTTLETIKVII-----LDKPGPPTGP 1065
Score = 35.1 bits (77), Expect = 0.19
Identities = 22/79 (27%), Positives = 35/79 (44%), Gaps = 2/79 (2%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G ++ V+G P P I W + A +++ + + L + +V D G YT E
Sbjct: 688 GASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTT--ESYSLLIVDKVNRYDAGKYTIE 745
Query: 66 ASNCLGKAKSNACLVVYHT 84
A N GK + + VY T
Sbjct: 746 AENQSGKKSATVLVKVYDT 764
Score = 31.9 bits (69), Expect = 1.8
Identities = 23/102 (22%), Positives = 43/102 (42%), Gaps = 4/102 (3%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVK-EKEEIMRILEIDEVSIEDVG 165
+ G ++ AV G P P W K + +++++ + +++ + S D G
Sbjct: 286 IRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRS--DSG 343
Query: 166 IYRITVENELGRAEASARLEVITRSGKFYGGLRAYSASPRKC 207
Y +TV+N G S ++V+ G G L + KC
Sbjct: 344 KYTLTVKNASGTKAVSVMVKVLDSPGP-CGKLTVSRVTQEKC 384
Score = 31.5 bits (68), Expect = 2.4
Identities = 24/86 (27%), Positives = 33/86 (38%), Gaps = 5/86 (5%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G + + V G P+P I W + + C Y A IK D G YT
Sbjct: 289 GSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLT 348
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPG 91
N G K+ + +V + L SPG
Sbjct: 349 VKNASG-TKAVSVMV----KVLDSPG 369
Score = 30.3 bits (65), Expect = 5.5
Identities = 18/65 (27%), Positives = 31/65 (47%), Gaps = 1/65 (1%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDD-GTARLKIKQVTAEDEGTYT 63
+G +V FE +V+G P P ++W + + + E ++ L I+ ED G Y
Sbjct: 3035 EGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYR 3094
Query: 64 CEASN 68
A+N
Sbjct: 3095 VTATN 3099
>M32292-1|AAA35751.1| 750|Homo sapiens protein ( Human colorectal
tumor suppressor mRNA (DCC), 5' end. ).
Length = 750
Score = 79.8 bits (188), Expect = 7e-15
Identities = 56/186 (30%), Positives = 84/186 (45%), Gaps = 17/186 (9%)
Query: 1 MLSCDGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEG 60
+++ +G EC V+G P P W EVI+ + S G + L I VT +D G
Sbjct: 249 VVAIEGKDAVLECCVSGYPPPSFTWLRGEEVIQLRSKKYSLL--GGSNLLISNVTDDDSG 306
Query: 61 TYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVK 120
YTC + ++A L V + P F +P N E ++ F+C V
Sbjct: 307 MYTCVVTYKNENISASAELTVL-----------VPPWFLNHPSNLYAYESMDIEFECTVS 355
Query: 121 GNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEA 180
G P P +W K+G ++ PS + +RIL + + D G Y+ ENE G A+
Sbjct: 356 GKPVPTVNWMKNGDVVIPSDYFQIVGGSN-LRILGVVK---SDEGFYQCVAENEAGNAQT 411
Query: 181 SARLEV 186
SA+L V
Sbjct: 412 SAQLIV 417
Score = 65.3 bits (152), Expect = 2e-10
Identities = 51/183 (27%), Positives = 75/183 (40%), Gaps = 9/183 (4%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
GDTV +C+V G P P I W + + + L+I ++ D G Y C
Sbjct: 154 GDTVLLKCEVIGEPMPTIHWQKNQQDLTPIPGDSRVVVLPSGALQISRLQPGDIGIYRCS 213
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A N N V R LS PG F P N V EG++ +C V G P P
Sbjct: 214 ARNPASSRTGNEAEV----RILSDPGLHRQLYFLQRPSNVVAIEGKDAVLECCVSGYPPP 269
Query: 126 WASWDKDGSII-TPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
+W + +I S + ++ ++ I V+ +D G+Y V + ASA L
Sbjct: 270 SFTWLRGEEVIQLRSKKYSLLGGSNLL----ISNVTDDDSGMYTCVVTYKNENISASAEL 325
Query: 185 EVI 187
V+
Sbjct: 326 TVL 328
Score = 45.2 bits (102), Expect = 2e-04
Identities = 39/138 (28%), Positives = 60/138 (43%), Gaps = 17/138 (12%)
Query: 58 DEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKC 117
DEG Y CEAS LG + S ++ T +++ G F + + G+ V KC
Sbjct: 111 DEGLYQCEAS--LGDSGS----IISRTAKVAVAG---PLRFLSQTESVTAFMGDTVLLKC 161
Query: 118 AVKGNPSPWASWDKDGSIITP---SARITVKEKEEIMRILEIDEVSIEDVGIYRITVENE 174
V G P P W K+ +TP +R+ V L+I + D+GIYR + N
Sbjct: 162 EVIGEPMPTIHWQKNQQDLTPIPGDSRVVVLPS----GALQISRLQPGDIGIYRCSARNP 217
Query: 175 L-GRAEASARLEVITRSG 191
R A + +++ G
Sbjct: 218 ASSRTGNEAEVRILSDPG 235
>AJ314896-1|CAC85745.1| 163|Homo sapiens obscurin protein.
Length = 163
Score = 79.0 bits (186), Expect = 1e-14
Identities = 43/128 (33%), Positives = 57/128 (44%), Gaps = 4/128 (3%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G CQ+ GNP P + W + + A F + D RL I + D G Y C
Sbjct: 24 GKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTILDLALGDSGQYVCR 83
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A N +G+A + L V + + AP F P + V EG TF+C V G+P P
Sbjct: 84 ARNAIGEAFAAVGLQV----DAEAACAEQAPHFLLRPTSIRVREGSEATFRCRVGGSPRP 139
Query: 126 WASWDKDG 133
SW KDG
Sbjct: 140 AVSWSKDG 147
Score = 62.1 bits (144), Expect = 1e-09
Identities = 32/100 (32%), Positives = 51/100 (51%), Gaps = 1/100 (1%)
Query: 87 LSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKE 146
+ P AP F T P VV G++ T C + GNP+P SW+KD + AR + +
Sbjct: 1 MDQPQFSGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQ 60
Query: 147 KEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
++ R+ +D +++ D G Y N +G A A+ L+V
Sbjct: 61 DGDLYRLTILD-LALGDSGQYVCRARNAIGEAFAAVGLQV 99
>AY877349-1|AAX70929.1| 1463|Homo sapiens cardiac peroxidase
protein.
Length = 1463
Score = 78.6 bits (185), Expect = 2e-14
Identities = 53/183 (28%), Positives = 83/183 (45%), Gaps = 17/183 (9%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFE--SSYDDGTARLKIKQVTAEDEGTYT 63
G+TV F C+ GNP P+I W H + D D + +DDGT L I+ D+G Y
Sbjct: 248 GNTVYFTCRAEGNPKPEIIWIHNNHSL-DLEDDTRLNVFDDGT--LMIRNTRESDQGVYQ 304
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
C A N G+AK+ + ++ Y S P + P+F P + V G + T +C G+P
Sbjct: 305 CMARNSAGEAKTQSAMLRYS----SLPAK---PSFVIQPQDTEVLIGTSTTLECMATGHP 357
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
P +W +D + +R L + ++ D G + N G +A+A
Sbjct: 358 HPLITWTRDNGLELDGSRHVATSSG-----LYLQNITQRDHGRFTCHANNSHGTVQAAAN 412
Query: 184 LEV 186
+ V
Sbjct: 413 IIV 415
Score = 67.3 bits (157), Expect = 4e-11
Identities = 53/187 (28%), Positives = 77/187 (41%), Gaps = 16/187 (8%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
VE+ C+ GNP P I W + + GT L+I + D+G Y C+A +
Sbjct: 436 VEWLCEADGNPPPVIVWTKTGGQL-PVEGQHTVLSSGT--LRIDRAAQHDQGQYECQAVS 492
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
LG K + L V P + F P + VE G+N+ C +G P P +
Sbjct: 493 SLGVKKVSVQLTV-------KP--KALAVFTQLPQDTSVEVGKNINISCHAQGEPQPIIT 543
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVIT 188
W+K+G IT S + V ++ L I + D G Y N G A + L V
Sbjct: 544 WNKEGVQITESGKFHVDDE----GTLTIYDAGFPDQGRYECVARNSFGLAVTNMFLTVTA 599
Query: 189 RSGKFYG 195
G+ G
Sbjct: 600 IQGRQAG 606
Score = 64.9 bits (151), Expect = 2e-10
Identities = 51/181 (28%), Positives = 75/181 (41%), Gaps = 19/181 (10%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G + EC TG+P P I W + D S + ++ L ++ +T D G +TC
Sbjct: 344 GTSTTLECMATGHPHPLITWTRDNGLELD----GSRHVATSSGLYLQNITQRDHGRFTCH 399
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A+N G ++ A ++V Q P F P ++VV E V + C GNP P
Sbjct: 400 ANNSHGTVQAAANIIV-----------QAPPQFTVTPKDQVVLEEHAVEWLCEADGNPPP 448
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
W K G + + TV L ID + D G Y + LG + S +L
Sbjct: 449 VIVWTKTGGQLPVEGQHTVLSS----GTLRIDRAAQHDQGQYECQAVSSLGVKKVSVQLT 504
Query: 186 V 186
V
Sbjct: 505 V 505
Score = 40.7 bits (91), Expect = 0.004
Identities = 25/76 (32%), Positives = 30/76 (39%), Gaps = 3/76 (3%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G + C G P P I W I + F D+GT L I D+G Y C
Sbjct: 525 GKNINISCHAQGEPQPIITWNKEGVQITESGKFHVD-DEGT--LTIYDAGFPDQGRYECV 581
Query: 66 ASNCLGKAKSNACLVV 81
A N G A +N L V
Sbjct: 582 ARNSFGLAVTNMFLTV 597
Score = 32.7 bits (71), Expect = 1.0
Identities = 22/92 (23%), Positives = 35/92 (38%), Gaps = 6/92 (6%)
Query: 95 APTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASW--DKDGSIITPSARITVKEKEEIMR 152
+P P + V G V F C +GNP P W + + R+ V + +M
Sbjct: 233 SPRITFEPQDVEVPSGNTVYFTCRAEGNPKPEIIWIHNNHSLDLEDDTRLNVFDDGTLM- 291
Query: 153 ILEIDEVSIEDVGIYRITVENELGRAEASARL 184
I D G+Y+ N G A+ + +
Sbjct: 292 ---IRNTRESDQGVYQCMARNSAGEAKTQSAM 320
>AL713647-1|CAD28458.1| 1232|Homo sapiens hypothetical protein
protein.
Length = 1232
Score = 77.0 bits (181), Expect = 5e-14
Identities = 48/166 (28%), Positives = 76/166 (45%), Gaps = 8/166 (4%)
Query: 22 DIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLGKAKSNACLVV 81
D +W + + ++ L IKQ + DEG TC + G K L +
Sbjct: 876 DAKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTL 935
Query: 82 YHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSAR 141
++ LS AP F + P ++ + EG+NV F C + G PSP W K+ I+ S+
Sbjct: 936 --SKELSD-----APAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSN 988
Query: 142 ITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVI 187
+++ + LEI S+ D G Y I +N G+ A+A L V+
Sbjct: 989 VSISRSRNVYS-LEIRNASVSDSGKYTIKAKNFRGQCSATASLMVL 1033
Score = 56.8 bits (131), Expect = 6e-08
Identities = 31/93 (33%), Positives = 43/93 (46%), Gaps = 1/93 (1%)
Query: 94 MAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRI 153
+A T P + V EGE+ F C G P P +W + G +++ SAR V +
Sbjct: 368 LAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQV-TTTKYKST 426
Query: 154 LEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
EI V D G Y + VEN G+ EA L +
Sbjct: 427 FEISSVQASDEGNYSVVVENSEGKQEAEFTLTI 459
Score = 51.6 bits (118), Expect = 2e-06
Identities = 24/77 (31%), Positives = 38/77 (49%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G V F C+++G P P+I WF I ++ S L+I+ + D G YT
Sbjct: 956 EGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTI 1015
Query: 65 EASNCLGKAKSNACLVV 81
+A N G+ + A L+V
Sbjct: 1016 KAKNFRGQCSATASLMV 1032
Score = 49.2 bits (112), Expect = 1e-05
Identities = 35/157 (22%), Positives = 69/157 (43%), Gaps = 7/157 (4%)
Query: 36 ADFESSYDDGTARLKIKQVTAEDEGTYT---CEASNCLGKAKSNACLVVYHTRRLSSPG- 91
+ F SS +K ++A+ + E S+ SN + T ++ G
Sbjct: 1074 SSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMTQLESSTSKMLKAGI 1133
Query: 92 RQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSII--TPSARITVKEKEE 149
R + P P + ++EG+ +T CA G P+P +W G I R ++ ++
Sbjct: 1134 RGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDD 1193
Query: 150 IMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
+ ++ +D V +D G+Y +++ NE G A+ + +
Sbjct: 1194 LTTLIIMD-VQKQDGGLYTLSLGNEFGSDSATVNIHI 1229
Score = 48.0 bits (109), Expect = 3e-05
Identities = 25/96 (26%), Positives = 42/96 (43%), Gaps = 4/96 (4%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G++ F C G P P + W +V+ A + + + +I V A DEG Y+
Sbjct: 383 EGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSV 442
Query: 65 EASNCLGKAKSNACLVVYHTR----RLSSPGRQMAP 96
N GK ++ L + R ++SP R +P
Sbjct: 443 VVENSEGKQEAEFTLTIQKARVTEKAVTSPPRVKSP 478
Score = 47.2 bits (107), Expect = 4e-05
Identities = 27/73 (36%), Positives = 36/73 (49%), Gaps = 3/73 (4%)
Query: 116 KCAVK--GNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVEN 173
K AVK G P P A W KDG IT + + E + LEI + D G+Y TV+N
Sbjct: 679 KFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGF-FLEIHKTDTSDSGLYTCTVKN 737
Query: 174 ELGRAEASARLEV 186
G +S +L +
Sbjct: 738 SAGSVSSSCKLTI 750
Score = 42.3 bits (95), Expect = 0.001
Identities = 21/72 (29%), Positives = 30/72 (41%)
Query: 10 EFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNC 69
+F + TG P P W + I ++ S D G L+I + D G YTC N
Sbjct: 679 KFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNS 738
Query: 70 LGKAKSNACLVV 81
G S+ L +
Sbjct: 739 AGSVSSSCKLTI 750
Score = 40.7 bits (91), Expect = 0.004
Identities = 18/56 (32%), Positives = 31/56 (55%), Gaps = 1/56 (1%)
Query: 22 DIRWFHYAEVIRDCADFESSYD-DGTARLKIKQVTAEDEGTYTCEASNCLGKAKSN 76
++ W+ + +++ F+ Y DGT LKI +T D+G + CE S G +K+N
Sbjct: 557 EVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEHVCEISGEGGTSKTN 612
Score = 40.3 bits (90), Expect = 0.005
Identities = 19/76 (25%), Positives = 32/76 (42%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G F V P +++W+H +++ + + G L+I +D GTY
Sbjct: 197 GQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAV 256
Query: 66 ASNCLGKAKSNACLVV 81
+N G+A A L V
Sbjct: 257 CTNYKGEASDYATLDV 272
Score = 36.7 bits (81), Expect = 0.063
Identities = 26/96 (27%), Positives = 38/96 (39%), Gaps = 1/96 (1%)
Query: 110 GENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRI 169
G+N F V+ P+ W +G + S++I ++ LEI + +D G YR
Sbjct: 197 GQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLT-LEILDCHTDDSGTYRA 255
Query: 170 TVENELGRAEASARLEVITRSGKFYGGLRAYSASPR 205
N G A A L+V Y R PR
Sbjct: 256 VCTNYKGEASDYATLDVTGGDYTTYASQRRDEEVPR 291
Score = 33.1 bits (72), Expect = 0.78
Identities = 23/85 (27%), Positives = 33/85 (38%), Gaps = 5/85 (5%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVI--RDCADFESSYDDGTARLKIKQVTAEDEGTY 62
+G + C TG P P++ W I ++ F D L I V +D G Y
Sbjct: 1151 EGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLY 1210
Query: 63 TCEASNCLGKAKSNACLVVYHTRRL 87
T N G S++ V H R +
Sbjct: 1211 TLSLGNEFG---SDSATVNIHIRSI 1232
>BC106713-1|AAI06714.1| 1505|Homo sapiens PTPRD protein protein.
Length = 1505
Score = 76.2 bits (179), Expect = 8e-14
Identities = 59/189 (31%), Positives = 84/189 (44%), Gaps = 9/189 (4%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTAR-LKIKQV-TAEDEGTYT 63
G F CQ TG+P P I W + + + +DDG+ L+I+ + T DE Y
Sbjct: 38 GGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYE 97
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
C ASN +G+ + L V ++ + PT P KVVE T CA GNP
Sbjct: 98 CVASNNVGEISVSTRLTVLREDQIP----RGFPTIDMGPQLKVVERTRTATMLCAASGNP 153
Query: 124 SPWASWDKDG-SIITPSARITVKE-KEEIMRILEIDEVSIEDVGIYRITVENELG-RAEA 180
P +W KD + T + +K+ + E + L+I++ D G Y N G R A
Sbjct: 154 DPEITWFKDFLPVDTSNNNGRIKQLRSESIGALQIEQSEESDQGKYECVATNSAGTRYSA 213
Query: 181 SARLEVITR 189
A L V R
Sbjct: 214 PANLYVRVR 222
Score = 62.1 bits (144), Expect = 1e-09
Identities = 46/182 (25%), Positives = 72/182 (39%), Gaps = 17/182 (9%)
Query: 8 TVEFECQVTGNPDPDIRWFHY---AEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
T C +GNPDP+I WF + + + + L+I+Q D+G Y C
Sbjct: 142 TATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGALQIEQSEESDQGKYEC 201
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
A+N G S + RR+ P F P N + G +V C G+P
Sbjct: 202 VATNSAGTRYSAPANLYVRVRRVP-------PRFSIPPTNHEIMPGGSVNITCVAVGSPM 254
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
P+ W +TP + + +LE+++V Y + LG EA A++
Sbjct: 255 PYVKWMLGAEDLTPEDDMPIGR-----NVLELNDV--RQSANYTCVAMSTLGVIEAIAQI 307
Query: 185 EV 186
V
Sbjct: 308 TV 309
Score = 40.7 bits (91), Expect = 0.004
Identities = 29/122 (23%), Positives = 48/122 (39%), Gaps = 2/122 (1%)
Query: 96 PTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILE 155
P F P ++ G +F C G+P P W+K G ++ ++ + +L
Sbjct: 24 PRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLR 83
Query: 156 IDEV-SIEDVGIYRITVENELGRAEASARLEVITRSGKFYGGLRAYSASPRKCLSYRRRP 214
I + + D IY N +G S RL V+ R + G P+ + R R
Sbjct: 84 IQPLRTPRDEAIYECVASNNVGEISVSTRLTVL-REDQIPRGFPTIDMGPQLKVVERTRT 142
Query: 215 ST 216
+T
Sbjct: 143 AT 144
Score = 29.5 bits (63), Expect = 9.6
Identities = 21/76 (27%), Positives = 32/76 (42%), Gaps = 6/76 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G +V C G+P P ++W AE + E G L++ V YTC
Sbjct: 240 GGSVNITCVAVGSPMPYVKWMLGAEDLTP----EDDMPIGRNVLELNDV--RQSANYTCV 293
Query: 66 ASNCLGKAKSNACLVV 81
A + LG ++ A + V
Sbjct: 294 AMSTLGVIEAIAQITV 309
>BC113118-1|AAI13119.1| 1028|Homo sapiens contactin 6 protein.
Length = 1028
Score = 75.8 bits (178), Expect = 1e-13
Identities = 53/186 (28%), Positives = 84/186 (45%), Gaps = 19/186 (10%)
Query: 8 TVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEAS 67
+V+ EC GNP PDI W + + Y A L+I EDEG Y C AS
Sbjct: 244 SVKLECFALGNPVPDISW---RRLDGSPLPGKVKYSKSQAILEIPNFQQEDEGFYECIAS 300
Query: 68 NCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWA 127
N G+ + L+ Y +P P + N + +N+ ++C G P+PW
Sbjct: 301 NLRGRNLAKGQLIFY------AP-----PEWEQKIQNTHLSIYDNLLWECKASGKPNPWY 349
Query: 128 SWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVI 187
+W K+G + P RI ++ I+ +L ++ D G+Y+ EN+ A+A L V+
Sbjct: 350 TWLKNGERLNPEERIQIENGTLIITML-----NVSDSGVYQCAAENKYQIIYANAELRVL 404
Query: 188 TRSGKF 193
+ F
Sbjct: 405 ASAPDF 410
Score = 50.4 bits (115), Expect = 5e-06
Identities = 50/186 (26%), Positives = 75/186 (40%), Gaps = 20/186 (10%)
Query: 7 DTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEA 66
D + +EC+ +G P+P W E + + ++GT L I + D G Y C A
Sbjct: 333 DNLLWECKASGKPNPWYTWLKNGERLN--PEERIQIENGT--LIITMLNVSDSGVYQCAA 388
Query: 67 SNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNK--VVEEGENVTFKCAVKGNPS 124
N +NA L R L+S AP F P K V+ G ++ C P
Sbjct: 389 ENKYQIIYANAEL-----RVLAS-----APDFSKSPVKKKSFVQVGGDIVIGCKPNAFPR 438
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
SW + + S RI + E L+I ++ D G Y N+ G A+ + L
Sbjct: 439 AAISWKRGTETLRQSKRIFLLEDGS----LKIYNITRSDAGSYTCIATNQFGTAKNTGSL 494
Query: 185 EVITRS 190
V R+
Sbjct: 495 IVKERT 500
Score = 48.8 bits (111), Expect = 1e-05
Identities = 49/185 (26%), Positives = 74/185 (40%), Gaps = 18/185 (9%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G + C+ P I W E +R +DG+ LKI +T D G+YTC
Sbjct: 424 GGDIVIGCKPNAFPRAAISWKRGTETLRQSKRI-FLLEDGS--LKIYNITRSDAGSYTCI 480
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A+N G AK+ L+V ++ P +M T GE++ C V +PS
Sbjct: 481 ATNQFGTAKNTGSLIVKERTVITVPPSKMDVTV-----------GESIVLPCQVSHDPSI 529
Query: 126 WA--SWDKDGSIITPSARITVKEK--EEIMRILEIDEVSIEDVGIYRITVENELGRAEAS 181
W +G +I + E+ E + L I + + G Y TV+ L A
Sbjct: 530 EVVFVWFFNGDVIDLKKGVAHFERIGGESVGDLMIRNIQLHHSGKYLCTVQTTLESLSAV 589
Query: 182 ARLEV 186
A + V
Sbjct: 590 ADIIV 594
Score = 41.5 bits (93), Expect = 0.002
Identities = 37/140 (26%), Positives = 50/140 (35%), Gaps = 6/140 (4%)
Query: 46 TARLKIKQVTAEDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNK 105
T L I +V D G YTC +N + R G +P
Sbjct: 178 TGNLYIAKVEPSDVGNYTCFITNKEAQRSVQGPPTPLVQRTDGVMGEYEPKIEVRFPETI 237
Query: 106 VVEEGENVTFKCAVKGNPSPWASWDK-DGSIITPSARITVKEKEEIMRILEIDEVSIEDV 164
+ +V +C GNP P SW + DGS + + + + ILEI ED
Sbjct: 238 QAAKDSSVKLECFALGNPVPDISWRRLDGSPLPGKVKYSKSQA-----ILEIPNFQQEDE 292
Query: 165 GIYRITVENELGRAEASARL 184
G Y N GR A +L
Sbjct: 293 GFYECIASNLRGRNLAKGQL 312
Score = 32.7 bits (71), Expect = 1.0
Identities = 19/63 (30%), Positives = 24/63 (38%), Gaps = 1/63 (1%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
V C G P P RW I + D G+ + T +D G Y C A+N
Sbjct: 46 VILNCAANGYPSPHYRWKQNGTDIDFTMSYHYRLDGGSLAINSPH-TDQDIGMYQCLATN 104
Query: 69 CLG 71
LG
Sbjct: 105 LLG 107
>AB003592-1|BAA82612.1| 1028|Homo sapiens neural adhesion molecule
NB-3 protein.
Length = 1028
Score = 75.8 bits (178), Expect = 1e-13
Identities = 53/186 (28%), Positives = 84/186 (45%), Gaps = 19/186 (10%)
Query: 8 TVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEAS 67
+V+ EC GNP PDI W + + Y A L+I EDEG Y C AS
Sbjct: 244 SVKLECFALGNPVPDISW---RRLDGSPLPGKVKYSKSQAILEIPNFQQEDEGFYECIAS 300
Query: 68 NCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWA 127
N G+ + L+ Y +P P + N + +N+ ++C G P+PW
Sbjct: 301 NLRGRNLAKGQLIFY------AP-----PEWEQKIQNTHLSIYDNLLWECKASGKPNPWY 349
Query: 128 SWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVI 187
+W K+G + P RI ++ I+ +L ++ D G+Y+ EN+ A+A L V+
Sbjct: 350 TWLKNGERLNPEERIQIENGTLIITML-----NVSDSGVYQCAAENKYQIIYANAELRVL 404
Query: 188 TRSGKF 193
+ F
Sbjct: 405 ASAPDF 410
Score = 50.4 bits (115), Expect = 5e-06
Identities = 50/186 (26%), Positives = 75/186 (40%), Gaps = 20/186 (10%)
Query: 7 DTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEA 66
D + +EC+ +G P+P W E + + ++GT L I + D G Y C A
Sbjct: 333 DNLLWECKASGKPNPWYTWLKNGERLN--PEERIQIENGT--LIITMLNVSDSGVYQCAA 388
Query: 67 SNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNK--VVEEGENVTFKCAVKGNPS 124
N +NA L R L+S AP F P K V+ G ++ C P
Sbjct: 389 ENKYQIIYANAEL-----RVLAS-----APDFSKSPVKKKSFVQVGGDIVIGCKPNAFPR 438
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
SW + + S RI + E L+I ++ D G Y N+ G A+ + L
Sbjct: 439 AAISWKRGTETLRQSKRIFLLEDGS----LKIYNITRSDAGSYTCIATNQFGTAKNTGSL 494
Query: 185 EVITRS 190
V R+
Sbjct: 495 IVKERT 500
Score = 48.8 bits (111), Expect = 1e-05
Identities = 49/185 (26%), Positives = 74/185 (40%), Gaps = 18/185 (9%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G + C+ P I W E +R +DG+ LKI +T D G+YTC
Sbjct: 424 GGDIVIGCKPNAFPRAAISWKRGTETLRQSKRI-FLLEDGS--LKIYNITRSDAGSYTCI 480
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A+N G AK+ L+V ++ P +M T GE++ C V +PS
Sbjct: 481 ATNQFGTAKNTGSLIVKERTVITVPPSKMDVTV-----------GESIVLPCQVSHDPSI 529
Query: 126 WA--SWDKDGSIITPSARITVKEK--EEIMRILEIDEVSIEDVGIYRITVENELGRAEAS 181
W +G +I + E+ E + L I + + G Y TV+ L A
Sbjct: 530 EVVFVWFFNGDVIDLKKGVAHFERIGGESVGDLMIRNIQLHHSGKYLCTVQTTLESLSAV 589
Query: 182 ARLEV 186
A + V
Sbjct: 590 ADIIV 594
Score = 41.5 bits (93), Expect = 0.002
Identities = 37/140 (26%), Positives = 50/140 (35%), Gaps = 6/140 (4%)
Query: 46 TARLKIKQVTAEDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNK 105
T L I +V D G YTC +N + R G +P
Sbjct: 178 TGNLYIAKVEPSDVGNYTCFITNKEAQRSVQGPPTPLVQRTDGVMGEYEPKIEVRFPETI 237
Query: 106 VVEEGENVTFKCAVKGNPSPWASWDK-DGSIITPSARITVKEKEEIMRILEIDEVSIEDV 164
+ +V +C GNP P SW + DGS + + + + ILEI ED
Sbjct: 238 QAAKDSSVKLECFALGNPVPDISWRRLDGSPLPGKVKYSKSQA-----ILEIPNFQQEDE 292
Query: 165 GIYRITVENELGRAEASARL 184
G Y N GR A +L
Sbjct: 293 GFYECIASNLRGRNLAKGQL 312
Score = 32.7 bits (71), Expect = 1.0
Identities = 19/63 (30%), Positives = 24/63 (38%), Gaps = 1/63 (1%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
V C G P P RW I + D G+ + T +D G Y C A+N
Sbjct: 46 VILNCAANGYPSPHYRWKQNGTDIDFTMSYHYRLDGGSLAINSPH-TDQDIGMYQCLATN 104
Query: 69 CLG 71
LG
Sbjct: 105 LLG 107
>BX928748-1|CAH74051.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone RP11-465I11 on chromosome 1. ).
Length = 5635
Score = 75.4 bits (177), Expect = 1e-13
Identities = 55/183 (30%), Positives = 78/183 (42%), Gaps = 10/183 (5%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G V C+ +GNP P + W E+I + S+ DG+ L + E+ G Y C
Sbjct: 994 EGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGS--LYVVSPGGEESGEYVC 1051
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
A+N G AK L VY R+ R ++ P V GE VT C VK P
Sbjct: 1052 TATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQD---KPVEISVLAGEEVTLPCEVKSLPP 1108
Query: 125 PWASWDKDGSIITP-SARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
P +W K+ +I+P S R T ++I E D G+Y N G + +
Sbjct: 1109 PIITWAKETQLISPFSPRHTFLPSGS----MKITETRTSDSGMYLCVATNIAGNVTQAVK 1164
Query: 184 LEV 186
L V
Sbjct: 1165 LNV 1167
Score = 74.5 bits (175), Expect = 3e-13
Identities = 48/178 (26%), Positives = 75/178 (42%), Gaps = 13/178 (7%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
V +C G P+P I W + + G L+I + ED G YTC A+N
Sbjct: 1844 VALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATN 1902
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G+ + + L V+ L G+ + N+ V V +C GNP P +
Sbjct: 1903 AAGETQQHIQLHVHEPPSLEDAGKML---------NETVLVSNPVQLECKAAGNPVPVIT 1953
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KD +++ S +T + + I++I+ I D GIY+ N G E L+V
Sbjct: 1954 WYKDNRLLSGSTSMTFLNRGQ---IIDIESAQISDAGIYKCVAINSAGATELFYSLQV 2008
Score = 70.9 bits (166), Expect = 3e-12
Identities = 60/180 (33%), Positives = 80/180 (44%), Gaps = 20/180 (11%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+ + C+ TG P P + W +I A F+S +G + L I++V+ ED GTY C
Sbjct: 4274 GEQLRLSCKATGIPLPKLTWTFNNNIIP--AHFDSV--NGHSELVIERVSKEDSGTYVCT 4329
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFY-TYPFNKVVEEGENVTFKCAVKGNPS 124
A N +G K A VY + P P F YP N + G N C VKG+P+
Sbjct: 4330 AENSVGFVK--AIGFVY----VKEP-----PVFKGDYPSNWIEPLGGNAILNCEVKGDPT 4378
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
P W++ G I S RI ++ L I ED G Y NE G E S L
Sbjct: 4379 PTIQWNRKGVDIEISHRI----RQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSL 4434
Score = 68.5 bits (160), Expect = 2e-11
Identities = 47/179 (26%), Positives = 78/179 (43%), Gaps = 13/179 (7%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
++ EC+ G P P I W+ + I + ++ Y D L I + D TYTC +N
Sbjct: 1565 IKLECETRGLPMPAITWYKDGQPIMSSS--QALYIDKGQYLHIPRAQVSDSATYTCHVAN 1622
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G A+ + + VY + +A P NK V ++T +C GNPSP +
Sbjct: 1623 VAGTAEKSFHVDVYVPPMIEG---NLAT-----PLNKQVVIAHSLTLECKAAGNPSPILT 1674
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVI 187
W KDG + + I ++ + + I+ E+ D G Y + G E ++V+
Sbjct: 1675 WLKDGVPVKANDNIRIEAGGKKLEIMSAQEI---DRGQYICVATSVAGEKEIKYEVDVL 1730
Score = 67.7 bits (158), Expect = 3e-11
Identities = 43/182 (23%), Positives = 79/182 (43%), Gaps = 11/182 (6%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G+ + C+ +G P P++ W + + G +L+I D Y+C
Sbjct: 2210 EGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSC 2269
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
ASN G AK L VY +++ G ++P +V G++++ +C V+G P
Sbjct: 2270 VASNVAGTAKKEYNLQVYIRPTITNSG--------SHPTEIIVTRGKSISLECEVQGIPP 2321
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
P +W KDG + + + + ++ IL++ + + D G Y N G + L
Sbjct: 2322 PTVTWMKDGHPLIKAKGVEILDEG---HILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDL 2378
Query: 185 EV 186
V
Sbjct: 2379 SV 2380
Score = 66.5 bits (155), Expect = 7e-11
Identities = 53/174 (30%), Positives = 73/174 (41%), Gaps = 16/174 (9%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFE-SSYDD-GTARLKIKQVTAEDEGTYT 63
G V C V G P+P I+W + F SS T L I + A D+GTY
Sbjct: 807 GSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYI 866
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCA-VKGN 122
CEA N GK +S + V +AP P V EG+ +T C + GN
Sbjct: 867 CEAENQFGKIQSETTVTVTGL---------VAPLIGISPSVANVIEGQQLTLPCTLLAGN 917
Query: 123 PSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG 176
P P W K+ +++ + ITV+ L I+ V ++D G Y N G
Sbjct: 918 PIPERRWIKNSAMLLQNPYITVRSDGS----LHIERVQLQDGGEYTCVASNVAG 967
Score = 66.5 bits (155), Expect = 7e-11
Identities = 50/178 (28%), Positives = 71/178 (39%), Gaps = 13/178 (7%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
V ECQV G P PDI WF + + D D L +K D+G Y C SN
Sbjct: 1471 VALECQVKGTPFPDIHWFKDGKPL-FLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSN 1529
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
GK + L +Y + T + N +++ +C +G P P +
Sbjct: 1530 AAGKQAKDIKLTIYIPPSIKGGN---VTTDISVLINSLIK------LECETRGLPMPAIT 1580
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KDG I S++ +K + L I + D Y V N G AE S ++V
Sbjct: 1581 WYKDGQPIMSSSQALYIDKGQ---YLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDV 1635
Score = 65.7 bits (153), Expect = 1e-10
Identities = 46/178 (25%), Positives = 74/178 (41%), Gaps = 12/178 (6%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
+ C+V+G P PD+ W + I+ + + G L+I + D G YTC A N
Sbjct: 2982 ISLTCEVSGFPPPDLSWLKNEQPIK--LNTNTLIVPGGRTLQIIRAKVSDGGEYTCIAIN 3039
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G++K L VY + + V EG +V+ +C P P +
Sbjct: 3040 QAGESKKKFSLTVYVPPSIKDHDSESLSVVN-------VREGTSVSLECESNAVPPPVIT 3092
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W K+G +IT S + + + +L I + + D G Y N GR + + L V
Sbjct: 3093 WYKNGRMITESTHVEILADGQ---MLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNV 3147
Score = 65.3 bits (152), Expect = 2e-10
Identities = 52/182 (28%), Positives = 75/182 (41%), Gaps = 14/182 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
GD EC+ +G P P ++WF +R D LKI++ D G YTC
Sbjct: 716 GDITVMECKTSGIPPPQVKWFKGDLELRPSTFL--IIDPLLGLLKIQETQDLDAGDYTCV 773
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A N G+A L V SP P F P + +E G NVT C V+G P P
Sbjct: 774 AINEAGRATGKITLDV------GSP-----PVFIQEPADVSMEIGSNVTLPCYVQGYPEP 822
Query: 126 WASWDKDGSIITPSARITVKEKEEIMR-ILEIDEVSIEDVGIYRITVENELGRAEASARL 184
W + ++ S +V ++ L I + D G Y EN+ G+ ++ +
Sbjct: 823 TIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTV 882
Query: 185 EV 186
V
Sbjct: 883 TV 884
Score = 64.9 bits (151), Expect = 2e-10
Identities = 57/198 (28%), Positives = 82/198 (41%), Gaps = 19/198 (9%)
Query: 5 DGDTVEFECQV-TGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYT 63
+G + C + GNP P+ RW + ++ + + DG+ L I++V +D G YT
Sbjct: 903 EGQQLTLPCTLLAGNPIPERRWIKNSAMLLQ-NPYITVRSDGS--LHIERVQLQDGGEYT 959
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
C ASN G +VV H G+Q+ T EG VT C GNP
Sbjct: 960 CVASNVAGTNNKTTSVVV-HVLPTIQHGQQILSTI----------EGIPVTLPCKASGNP 1008
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
P W K G +I+ S + K L + E+ G Y T N G A+ +
Sbjct: 1009 KPSVIWSKKGELISTS---SAKFSAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKVQ 1065
Query: 184 LEVITRSGKFYGGLRAYS 201
L V R + +G R S
Sbjct: 1066 LTVYVRP-RVFGDQRGLS 1082
Score = 63.7 bits (148), Expect = 5e-10
Identities = 53/181 (29%), Positives = 70/181 (38%), Gaps = 17/181 (9%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G V C TG P P I W I + + DGT L IK +D G Y C
Sbjct: 626 GSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMT-SDGT--LFIKNAAPKDAGIYGCL 682
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
ASN G K N+ L R + AP +V G+ +C G P P
Sbjct: 683 ASNSAGTDKQNSTL-----RYIE------APKLMVVQSELLVALGDITVMECKTSGIPPP 731
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
W K + PS + + + ++ +L+I E D G Y NE GRA L+
Sbjct: 732 QVKWFKGDLELRPSTFLII---DPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLD 788
Query: 186 V 186
V
Sbjct: 789 V 789
Score = 63.7 bits (148), Expect = 5e-10
Identities = 47/178 (26%), Positives = 78/178 (43%), Gaps = 14/178 (7%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
+E +C VTG+P P I W ++I + F+ + +L I Q + G Y C A+N
Sbjct: 1752 LELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNG--RKLVIAQAQVSNTGLYRCMAAN 1809
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G K + V+ + S G +VV + + V +C G P+P +
Sbjct: 1810 TAGDHKKEFEVTVHVPPTIKSSGLS----------ERVVVKYKPVALQCIANGIPNPSIT 1859
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KD + +A+ +K + R+L+I + +ED G Y N G + +L V
Sbjct: 1860 WLKDDQPVN-TAQGNLKIQSS-GRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHV 1915
Score = 63.3 bits (147), Expect = 6e-10
Identities = 47/182 (25%), Positives = 73/182 (40%), Gaps = 13/182 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G ++ EC+V G P P + W + E D+G L++K + D G Y C
Sbjct: 2307 GKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEI-LDEGHI-LQLKNIHVSDTGRYVCV 2364
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A N G L V+ + R P N V E +V+ C G P P
Sbjct: 2365 AVNVAGMTDKKYDLSVHAPPSIIGNHRS--------PENISVVEKNSVSLTCEASGIPLP 2416
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
+W KDG ++ S + + ++R++ + ++ED G Y V N G L
Sbjct: 2417 SITWFKDGWPVSLSNSVRILSGGRMLRLM---QTTMEDAGQYTCVVRNAAGEERKIFGLS 2473
Query: 186 VI 187
V+
Sbjct: 2474 VL 2475
Score = 62.9 bits (146), Expect = 8e-10
Identities = 50/179 (27%), Positives = 71/179 (39%), Gaps = 13/179 (7%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
+EF C G P P I+W H + S +DGT L I VT D G Y C A N
Sbjct: 1284 IEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGTL-LVIASVTPYDNGEYICVAVN 1342
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G + L V H + Q+ N V + C V+G PSP
Sbjct: 1343 EAGTTERKYNLKV-HVPPVIKDKEQVT--------NVSVLLNQLTNLFCEVEGTPSPIIM 1393
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVI 187
W KD +T S+ I +I+++ + ED G Y N G ++ ++V+
Sbjct: 1394 WYKDNVQVTESSTIQTVNNGKILKLF---RATPEDAGRYSCKAINIAGTSQKYFNIDVL 1449
Score = 62.1 bits (144), Expect = 1e-09
Identities = 52/182 (28%), Positives = 71/182 (39%), Gaps = 12/182 (6%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G V+ C G P P I W + + S DGT L I Q T D G YTC
Sbjct: 1185 GQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGT--LSIDQATPSDAGIYTCV 1242
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A+N G ++ L V + + P + T +V + + F C KG P P
Sbjct: 1243 ATNIAGTDETEITLHVQEPPTVED----LEPPYNTTFQERVANQ--RIEFPCPAKGTPKP 1296
Query: 126 WASWDKDGSIIT-PSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
W +G +T I++ E +L I V+ D G Y NE G E L
Sbjct: 1297 TIKWLHNGRELTGREPGISILEDG---TLLVIASVTPYDNGEYICVAVNEAGTTERKYNL 1353
Query: 185 EV 186
+V
Sbjct: 1354 KV 1355
Score = 61.7 bits (143), Expect = 2e-09
Identities = 47/181 (25%), Positives = 68/181 (37%), Gaps = 16/181 (8%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+ V C+V P P I W ++I + + G+ +KI + D G Y C
Sbjct: 1094 GEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGS--MKITETRTSDSGMYLCV 1151
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A+N G L V+ + P P + V+ G+ V C +G P P
Sbjct: 1152 ATNIAGNVTQAVKLNVH-----------VPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLP 1200
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
+W K GS + V + L ID+ + D GIY N G E L
Sbjct: 1201 VITWSKGGSTMLVDGEHHVSNPD---GTLSIDQATPSDAGIYTCVATNIAGTDETEITLH 1257
Query: 186 V 186
V
Sbjct: 1258 V 1258
Score = 61.3 bits (142), Expect = 3e-09
Identities = 50/178 (28%), Positives = 64/178 (35%), Gaps = 10/178 (5%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
V C TG P P I W + I + E G ++L+I + D G YTC ASN
Sbjct: 3169 VTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASN 3228
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
GKA+ Y+ + P P + V GENV C G P+P
Sbjct: 3229 MEGKAQK------YYFLSIQVPPSVAGAEI---PSDVSVLLGENVELVCNANGIPTPLIQ 3279
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KDG I ++ L I D G Y N G + L V
Sbjct: 3280 WLKDGKPIASGETERIRVSAN-GSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNV 3336
Score = 60.1 bits (139), Expect = 6e-09
Identities = 48/168 (28%), Positives = 73/168 (43%), Gaps = 18/168 (10%)
Query: 13 CQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLGK 72
C G P P I W ++ + ++ G L ++ V ED G YTC A+N G+
Sbjct: 4190 CVADGIPTPAINWKKDNVLLANLLGKYTAEPYG--ELILENVVLEDSGFYTCVANNAAGE 4247
Query: 73 AKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKD 132
L V+ + PTF P + + +GE + C G P P +W +
Sbjct: 4248 DTHTVSLTVH-----------VLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFN 4296
Query: 133 GSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEA 180
+II P+ +V E++ I+ VS ED G Y T EN +G +A
Sbjct: 4297 NNII-PAHFDSVNGHSELV----IERVSKEDSGTYVCTAENSVGFVKA 4339
Score = 58.0 bits (134), Expect = 2e-08
Identities = 44/175 (25%), Positives = 75/175 (42%), Gaps = 15/175 (8%)
Query: 13 CQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLGK 72
C+V G P P I W+ + + + ++ ++G LK+ + T ED G Y+C+A N G
Sbjct: 1382 CEVEGTPSPIIMWYKDNVQVTESSTIQT-VNNGKI-LKLFRATPEDAGRYSCKAINIAGT 1439
Query: 73 AKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKD 132
++ Y + P + F P V +V +C VKG P P W KD
Sbjct: 1440 SQK------YFNIDVLVPPTIIGTNF---PNEVSVVLNRDVALECQVKGTPFPDIHWFKD 1490
Query: 133 GS-IITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
G + + + ++ + +L + D G Y+ TV N G+ +L +
Sbjct: 1491 GKPLFLGDPNVELLDRGQ---VLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTI 1542
Score = 57.6 bits (133), Expect = 3e-08
Identities = 49/176 (27%), Positives = 69/176 (39%), Gaps = 15/176 (8%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G +V EC+ P P I W+ +I + E D L IK+ D G Y C
Sbjct: 3073 EGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADG--QMLHIKKAEVSDTGQYVC 3130
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGEN-VTFKCAVKGNP 123
A N G+ N L VY + P R++ +VE N VT C G P
Sbjct: 3131 RAINVAGRDDKNFHLNVYVPPSIEGPEREV-----------IVETISNPVTLTCDATGIP 3179
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAE 179
P +W K+ I S + V+ + L+I D G Y N G+A+
Sbjct: 3180 PPTIAWLKNHKRIENSDSLEVRILSGGSK-LQIARSQHSDSGNYTCIASNMEGKAQ 3234
Score = 57.2 bits (132), Expect = 4e-08
Identities = 54/200 (27%), Positives = 74/200 (37%), Gaps = 29/200 (14%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSY---DDGTARLKIKQVTAEDEGTY 62
G C+V G+P P I+W R D E S+ G L I ED G Y
Sbjct: 4364 GGNAILNCEVKGDPTPTIQWN------RKGVDIEISHRIRQLGNGSLAIYGTVNEDAGDY 4417
Query: 63 TCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGN 122
TC A+N G + + L L SP P P V+ G + C G
Sbjct: 4418 TCVATNEAGVVERSMSLT------LQSP-----PIITLEPVETVINAGGKIILNCQATGE 4466
Query: 123 PSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASA 182
P P +W + G I+ R+ V L I + ED + N +G
Sbjct: 4467 PQPTITWSRQGHSISWDDRVNVLSNNS----LYIADAQKEDTSEFECVARNLMG--SVLV 4520
Query: 183 RLEVITRSGKFYGGLRAYSA 202
R+ VI + +GG +SA
Sbjct: 4521 RVPVIV---QVHGGFSQWSA 4537
Score = 56.8 bits (131), Expect = 6e-08
Identities = 48/178 (26%), Positives = 69/178 (38%), Gaps = 17/178 (9%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
+ C+ G P PDI W I + + G+ L+I V D G YTC A+N
Sbjct: 4096 ITLSCEADGLPPPDITWHKDGRAIVESIR-QRVLSSGS--LQIAFVQPGDAGHYTCMAAN 4152
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G + ++ L V+ R+ S YT V E C G P+P +
Sbjct: 4153 VAGSSSTSTKLTVHVPPRIRS-----TEGHYT------VNENSQAILPCVADGIPTPAIN 4201
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KD ++ A + K E L ++ V +ED G Y N G + L V
Sbjct: 4202 WKKDNVLL---ANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHTVSLTV 4256
Score = 56.4 bits (130), Expect = 7e-08
Identities = 46/181 (25%), Positives = 70/181 (38%), Gaps = 11/181 (6%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+ VE C G P P I+W + I + L I D G YTC
Sbjct: 3261 GENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCV 3320
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A+N G+ L VY T + + A T +V+ N+ +C G P P
Sbjct: 3321 ATNPAGEEDRIFNLNVYVTPTIRG-NKDEAEKLMT-----LVDTSINI--ECRATGTPPP 3372
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
+W K+G + S+ I + +++RI+ + DV +Y N G L+
Sbjct: 3373 QINWLKNGLPLPLSSHIRLLAAGQVIRIV---RAQVSDVAVYTCVASNRAGVDNKHYNLQ 3429
Query: 186 V 186
V
Sbjct: 3430 V 3430
Score = 56.4 bits (130), Expect = 7e-08
Identities = 49/174 (28%), Positives = 63/174 (36%), Gaps = 17/174 (9%)
Query: 13 CQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLGK 72
C+ TG P P I W + + G L+I + ED GTY C A N G
Sbjct: 4009 CEATGTPSPFITWQKEGINVNTSGRNHAVLPSGG--LQISRAVREDAGTYMCVAQNPAGT 4066
Query: 73 AKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKD 132
A L V Q+ P + V+ + +T C G P P +W KD
Sbjct: 4067 ALGKIKLNV-----------QVPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKD 4115
Query: 133 GSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
G I S R V L+I V D G Y N G + S +L V
Sbjct: 4116 GRAIVESIRQRVLSSGS----LQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTV 4165
Score = 56.0 bits (129), Expect = 1e-07
Identities = 45/180 (25%), Positives = 72/180 (40%), Gaps = 14/180 (7%)
Query: 8 TVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEAS 67
++ EC+ TG P P I W + + R+ QV+ D YTC AS
Sbjct: 3359 SINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVS--DVAVYTCVAS 3416
Query: 68 NCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWA 127
N G + L V+ + + M T V +G + + C G P+P
Sbjct: 3417 NRAGVDNKHYNLQVFAPPNMDN---SMGTEEIT------VLKGSSTSMACITDGTPAPSM 3467
Query: 128 SWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVI 187
+W +DG + A +TV ++++L+ + ED G Y NE G L+V+
Sbjct: 3468 AWLRDGQPLGLDAHLTVSTHGMVLQLLKAE---TEDSGKYTCIASNEAGEVSKHFILKVL 3524
Score = 55.6 bits (128), Expect = 1e-07
Identities = 48/183 (26%), Positives = 70/183 (38%), Gaps = 16/183 (8%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
VE CQ P P + W + S + + LKI+ +D G YTCEA+N
Sbjct: 2121 VELLCQSDAIPPPTLTWLKDGHPLLKKPGL--SISENRSVLKIEDAQVQDTGRYTCEATN 2178
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
GK + N + ++ + T V EG ++ C G P P
Sbjct: 2179 VAGKTEKNYNVNIWVPPNIGGSDELTQLT---------VIEGNLISLLCESSGIPPPNLI 2229
Query: 129 WDKDGS-IITPS-ARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W K GS ++T S R+ + R L+I D +Y N G A+ L+V
Sbjct: 2230 WKKKGSPVLTDSMGRVRILSGG---RQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQV 2286
Query: 187 ITR 189
R
Sbjct: 2287 YIR 2289
Score = 55.2 bits (127), Expect = 2e-07
Identities = 48/180 (26%), Positives = 66/180 (36%), Gaps = 14/180 (7%)
Query: 7 DTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEA 66
++V C+ +G P P I WF + G L++ Q T ED G YTC
Sbjct: 2402 NSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRIL--SGGRMLRLMQTTMEDAGQYTCVV 2459
Query: 67 SNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPW 126
N G+ + ++ L P T V+E ++VT C V GNP P
Sbjct: 2460 RNAAGEERK-----IFGLSVLVPPHIVGENTLEDVK----VKEKQSVTLTCEVTGNPVPE 2510
Query: 127 ASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
+W KDG P R L+I V + G Y + G S L V
Sbjct: 2511 ITWHKDGQ---PLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNV 2567
Score = 54.4 bits (125), Expect = 3e-07
Identities = 43/169 (25%), Positives = 67/169 (39%), Gaps = 11/169 (6%)
Query: 8 TVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEAS 67
+V C+VTGNP P+I W + +++ D G L+I V G YTC AS
Sbjct: 2496 SVTLTCEVTGNPVPEITWHKDGQPLQE--DEAHHIISGGRFLQITNVQVPHTGRYTCLAS 2553
Query: 68 NCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWA 127
+ G + L V+ + ++ G P T N + C P
Sbjct: 2554 SPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILN------SPTSLVCEAYSYPPATI 2607
Query: 128 SWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG 176
+W KDG+ + + I + ++IL E ++ G Y NE G
Sbjct: 2608 TWFKDGTPLESNRNIRILPGGRTLQILNAQE---DNAGRYSCVATNEAG 2653
Score = 54.4 bits (125), Expect = 3e-07
Identities = 43/173 (24%), Positives = 72/173 (41%), Gaps = 10/173 (5%)
Query: 7 DTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEA 66
+T+ EC+ P + W+ + ++ + + T L+IK+ D G YTC A
Sbjct: 2690 NTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHT--LQIKEAQISDTGRYTCVA 2747
Query: 67 SNCLGKAKSNACL---VVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
SN G+ + + + V ++L G M T V+ ++ C P
Sbjct: 2748 SNIAGEDELDFDVNIQVPPSFQKLWEIG-NMLDTGRNGEAKDVIINNP-ISLYCETNAAP 2805
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG 176
P +W KDG +T S ++ + R+L+I +ED G Y NE G
Sbjct: 2806 PPTLTWYKDGHPLTSSDKVLILPGG---RVLQIPRAKVEDAGRYTCVAVNEAG 2855
Score = 53.6 bits (123), Expect = 5e-07
Identities = 40/178 (22%), Positives = 66/178 (37%), Gaps = 15/178 (8%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
V EC+ G P P + W + ++ G L + D G YTC A N
Sbjct: 2029 VRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRI-LALTSAQISDTGRYTCVAVN 2087
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G+ + + L VY + P N V + V C P P +
Sbjct: 2088 AAGEKQRDIDLRVY-----------VPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLT 2136
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KDG + +++ E +L+I++ ++D G Y N G+ E + + +
Sbjct: 2137 WLKDGHPLLKKPGLSISENRS---VLKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNI 2191
Score = 52.8 bits (121), Expect = 9e-07
Identities = 46/179 (25%), Positives = 67/179 (37%), Gaps = 18/179 (10%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
V EC+ P P I W E ++ A G L+I D YTC ASN
Sbjct: 3639 VTLECKSDAVPPPVITWLRNGERLQ--ATPRVRILSGGRYLQINNADLGDTANYTCVASN 3696
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
GK L V + P P + V+ ++ +C +G P+P +
Sbjct: 3697 IAGKTTREFILTV-----------NVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRIT 3745
Query: 129 WDKDGSIITPS-ARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KDG+++ + AR ++ E L I + D G Y N G L+V
Sbjct: 3746 WRKDGAVLAGNHARYSILEN----GFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQV 3800
Score = 52.0 bits (119), Expect = 2e-06
Identities = 47/178 (26%), Positives = 68/178 (38%), Gaps = 12/178 (6%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
+ C+ P P + W+ + +D G L+I + ED G YTC A N
Sbjct: 2795 ISLYCETNAAPPPTLTWYKDGHPLTS-SDKVLILPGGRV-LQIPRAKVEDAGRYTCVAVN 2852
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G+ + Y R L P + A + P V ++ +C G+P+P S
Sbjct: 2853 EAGEDS-----LQYDVRVLVPPIIKGANS--DLPEEVTVLVNKSALIECLSSGSPAPRNS 2905
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KDG + RIL+I I D+G Y EN G A+ L V
Sbjct: 2906 WQKDGQPLLEDDHHKFLSNG---RILQILNTQITDIGRYVCVAENTAGSAKKYFNLNV 2960
Score = 50.8 bits (116), Expect = 4e-06
Identities = 45/179 (25%), Positives = 68/179 (37%), Gaps = 17/179 (9%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
V+ EC+ GNP P I W+ ++ ++ + + I+ D G Y C A N
Sbjct: 1938 VQLECKAAGNPVPVITWYKDNRLLSGSTSM--TFLNRGQIIDIESAQISDAGIYKCVAIN 1995
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G + L V+ +S +A V V +C +G P+P +
Sbjct: 1996 SAGATELFYSLQVHVAPSISGSNNMVA-----------VVVNNPVRLECEARGIPAPSLT 2044
Query: 129 WDKDGSIITP-SARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KDGS ++ S + V RIL + I D G Y N G + L V
Sbjct: 2045 WLKDGSPVSSFSNGLQVLSGG---RILALTSAQISDTGRYTCVAVNAAGEKQRDIDLRV 2100
Score = 48.8 bits (111), Expect = 1e-05
Identities = 40/171 (23%), Positives = 68/171 (39%), Gaps = 18/171 (10%)
Query: 8 TVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEAS 67
++ EC+ GNP P + W ++ A+ + G +L+I D G Y C A+
Sbjct: 1658 SLTLECKAAGNPSPILTWLKDGVPVK--ANDNIRIEAGGKKLEIMSAQEIDRGQYICVAT 1715
Query: 68 NCLGKAKSNACLVVYHTRRLSSPGRQMA--PTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
+ G+ + + Y L P + +++ N ++E C V G+P P
Sbjct: 1716 SVAGEKE-----IKYEVDVLVPPAIEGGDETSYFIVMVNNLLE------LDCHVTGSPPP 1764
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG 176
W KDG +I + R L I + + + G+YR N G
Sbjct: 1765 TIMWLKDGQLIDERDGFKILLNG---RKLVIAQAQVSNTGLYRCMAANTAG 1812
Score = 47.6 bits (108), Expect = 3e-05
Identities = 43/174 (24%), Positives = 57/174 (32%), Gaps = 16/174 (9%)
Query: 13 CQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLGK 72
C +G P P I W + D G + Q+ G YTC A N G
Sbjct: 3918 CTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQLN--HAGRYTCVARNAAGS 3975
Query: 73 AKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKD 132
A + L V+ P P V + C G PSP+ +W K+
Sbjct: 3976 AHRHVTLHVHEP-----------PVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKE 4024
Query: 133 GSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
G + S R L+I ED G Y +N G A +L V
Sbjct: 4025 GINVNTSGR---NHAVLPSGGLQISRAVREDAGTYMCVAQNPAGTALGKIKLNV 4075
Score = 47.2 bits (107), Expect = 4e-05
Identities = 48/180 (26%), Positives = 67/180 (37%), Gaps = 24/180 (13%)
Query: 12 ECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLG 71
EC G P P I W V+ S ++G ++ VT D G Y C A+N G
Sbjct: 3733 ECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLHIQSAHVT--DTGRYLCMATNAAG 3790
Query: 72 KAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDK 131
+ L V H +PG P N V T C G P P +W K
Sbjct: 3791 TDRRRIDLQV-HVPPSIAPG----------PTNMTVIVNVQTTLACEATGIPKPSINWRK 3839
Query: 132 DGSIITPSARITVKEKEEIMRILE-----IDEVSIEDVGIYRITVENELGRAEASARLEV 186
+G + + V + + R+L I S++D Y TV N G + + L V
Sbjct: 3840 NGHL------LNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGDDKRTVDLTV 3893
Score = 46.8 bits (106), Expect = 6e-05
Identities = 38/171 (22%), Positives = 63/171 (36%), Gaps = 14/171 (8%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G + C G P P + W + + D + L++ + ED G YTC
Sbjct: 3450 GSSTSMACITDGTPAPSMAWLRDGQPLG--LDAHLTVSTHGMVLQLLKAETEDSGKYTCI 3507
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
ASN G+ + L V ++ + +V +T C G P+P
Sbjct: 3508 ASNEAGEVSKHFILKVLEPPHINGSEEHEE-------ISVIVNNPLELT--CIASGIPAP 3558
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG 176
+W KDG + + ++ E++R I +ED G Y + G
Sbjct: 3559 KMTWMKDGRPLPQTDQVQTLGGGEVLR---ISTAQVEDTGRYTCLASSPAG 3606
Score = 42.3 bits (95), Expect = 0.001
Identities = 41/176 (23%), Positives = 60/176 (34%), Gaps = 18/176 (10%)
Query: 13 CQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLGK 72
C+ TG P P I W ++ + S + L I + +D TY C +N G
Sbjct: 3825 CEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGD 3884
Query: 73 AKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKD 132
K L V Q+ P+ P + +V + C G P P W K+
Sbjct: 3885 DKRTVDLTV-----------QVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKN 3933
Query: 133 GSIITPSARITVKEKEEIMR--ILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
G + P + I+ +EI + G Y N G A L V
Sbjct: 3934 GIRLLPRG-----DGYRILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHV 3984
Score = 41.9 bits (94), Expect = 0.002
Identities = 38/167 (22%), Positives = 59/167 (35%), Gaps = 8/167 (4%)
Query: 13 CQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLGK 72
C+ P I WF + + G L+I ++ G Y+C A+N G+
Sbjct: 2597 CEAYSYPPATITWFKDGTPLESNRNIRIL--PGGRTLQILNAQEDNAGRYSCVATNEAGE 2654
Query: 73 AKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKD 132
+ + VY + + G P P ++ +T +C PS SW KD
Sbjct: 2655 MIKHYEVKVY-IPPIINKGDLWGPGLS--PKEVKIKVNNTLTLECEAYAIPSASLSWYKD 2711
Query: 133 GSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAE 179
G + + + L+I E I D G Y N G E
Sbjct: 2712 GQPLKSDDHVNIAANG---HTLQIKEAQISDTGRYTCVASNIAGEDE 2755
Score = 40.7 bits (91), Expect = 0.004
Identities = 36/169 (21%), Positives = 61/169 (36%), Gaps = 14/169 (8%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
+E C +G P P + W + ++ G L+I ED G YTC AS+
Sbjct: 3546 LELTCIASGIPAPKMTWMKDGRPLPQTDQVQTL--GGGEVLRISTAQVEDTGRYTCLASS 3603
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G + V+ ++ P + V VT +C P P +
Sbjct: 3604 PAGDDDKEYLVRVHVPPNIAGTDE---------PRDITVLRNRQVTLECKSDAVPPPVIT 3654
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGR 177
W ++G + + R+ + R L+I+ + D Y N G+
Sbjct: 3655 WLRNGERLQATPRVRILSGG---RYLQINNADLGDTANYTCVASNIAGK 3700
Score = 40.3 bits (90), Expect = 0.005
Identities = 34/139 (24%), Positives = 52/139 (37%), Gaps = 15/139 (10%)
Query: 49 LKIKQVTAEDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVE 108
L++K V D G Y C S+ G + ++ L V Q P P N+
Sbjct: 576 LELKSVKFNDAGEYHCMVSSEGGSSAASVFLTV-----------QEPPKVTVMPKNQSFT 624
Query: 109 EGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYR 168
G V+ C+ G P P +W + I S R + + I + +D GIY
Sbjct: 625 GGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGTLF----IKNAAPKDAGIYG 680
Query: 169 ITVENELGRAEASARLEVI 187
N G + ++ L I
Sbjct: 681 CLASNSAGTDKQNSTLRYI 699
Score = 39.9 bits (89), Expect = 0.007
Identities = 43/175 (24%), Positives = 63/175 (36%), Gaps = 15/175 (8%)
Query: 12 ECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLG 71
EC +G+P P W + + + D +G L+I D G Y C A N G
Sbjct: 2893 ECLSSGSPAPRNSWQKDGQPLLE-DDHHKFLSNGRI-LQILNTQITDIGRYVCVAENTAG 2950
Query: 72 KAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDK 131
AK L V+ + P + N V ++ C V G P P SW K
Sbjct: 2951 SAKKYFNLNVHVPPSVIGPKSE----------NLTVVVNNFISLTCEVSGFPPPDLSWLK 3000
Query: 132 DGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
+ I + + R L+I + D G Y N+ G ++ L V
Sbjct: 3001 NEQPIKLNTNTLIVPGG---RTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTV 3052
Score = 39.1 bits (87), Expect = 0.012
Identities = 35/144 (24%), Positives = 53/144 (36%), Gaps = 13/144 (9%)
Query: 43 DDGTARLKIKQVTAEDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYP 102
+ + L I +VT DEG Y C A + G ++ V S P P P
Sbjct: 478 ESASVNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDV------SEP-----PPVIQVP 526
Query: 103 FNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIE 162
N V GE C + +W ++ + + ++ + LE+ V
Sbjct: 527 NNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLS--LELKSVKFN 584
Query: 163 DVGIYRITVENELGRAEASARLEV 186
D G Y V +E G + AS L V
Sbjct: 585 DAGEYHCMVSSEGGSSAASVFLTV 608
>BC106716-1|AAI06717.1| 1496|Homo sapiens PTPRD protein protein.
Length = 1496
Score = 75.4 bits (177), Expect = 1e-13
Identities = 58/186 (31%), Positives = 83/186 (44%), Gaps = 9/186 (4%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTAR-LKIKQV-TAEDEGTYT 63
G F CQ TG+P P I W + + + +DDG+ L+I+ + T DE Y
Sbjct: 38 GGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYE 97
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
C ASN +G+ + L V ++ + PT P KVVE T CA GNP
Sbjct: 98 CVASNNVGEISVSTRLTVLREDQIP----RGFPTIDMGPQLKVVERTRTATMLCAASGNP 153
Query: 124 SPWASWDKDG-SIITPSARITVKE-KEEIMRILEIDEVSIEDVGIYRITVENELG-RAEA 180
P +W KD + T + +K+ + E + L+I++ D G Y N G R A
Sbjct: 154 DPEITWFKDFLPVDTSNNNGRIKQLRSESIGALQIEQSEESDQGKYECVATNSAGTRYSA 213
Query: 181 SARLEV 186
A L V
Sbjct: 214 PANLYV 219
Score = 65.3 bits (152), Expect = 2e-10
Identities = 48/183 (26%), Positives = 77/183 (42%), Gaps = 15/183 (8%)
Query: 8 TVEFECQVTGNPDPDIRWFHY---AEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
T C +GNPDP+I WF + + + + L+I+Q D+G Y C
Sbjct: 142 TATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGALQIEQSEESDQGKYEC 201
Query: 65 EASNCLG-KAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
A+N G + + A L V R + R++ P F P N + G +V C G+P
Sbjct: 202 VATNSAGTRYSAPANLYVRELREV----RRVPPRFSIPPTNHEIMPGGSVNITCVAVGSP 257
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
P+ W +TP + + +LE+++V Y + LG EA A+
Sbjct: 258 MPYVKWMLGAEDLTPEDDMPIGR-----NVLELNDV--RQSANYTCVAMSTLGVIEAIAQ 310
Query: 184 LEV 186
+ V
Sbjct: 311 ITV 313
Score = 40.7 bits (91), Expect = 0.004
Identities = 29/122 (23%), Positives = 48/122 (39%), Gaps = 2/122 (1%)
Query: 96 PTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILE 155
P F P ++ G +F C G+P P W+K G ++ ++ + +L
Sbjct: 24 PRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLR 83
Query: 156 IDEV-SIEDVGIYRITVENELGRAEASARLEVITRSGKFYGGLRAYSASPRKCLSYRRRP 214
I + + D IY N +G S RL V+ R + G P+ + R R
Sbjct: 84 IQPLRTPRDEAIYECVASNNVGEISVSTRLTVL-REDQIPRGFPTIDMGPQLKVVERTRT 142
Query: 215 ST 216
+T
Sbjct: 143 AT 144
Score = 29.5 bits (63), Expect = 9.6
Identities = 21/76 (27%), Positives = 32/76 (42%), Gaps = 6/76 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G +V C G+P P ++W AE + E G L++ V YTC
Sbjct: 244 GGSVNITCVAVGSPMPYVKWMLGAEDLTP----EDDMPIGRNVLELNDV--RQSANYTCV 297
Query: 66 ASNCLGKAKSNACLVV 81
A + LG ++ A + V
Sbjct: 298 AMSTLGVIEAIAQITV 313
>BC104812-1|AAI04813.1| 1501|Homo sapiens protein tyrosine
phosphatase, receptor type, S protein.
Length = 1501
Score = 75.4 bits (177), Expect = 1e-13
Identities = 59/193 (30%), Positives = 80/193 (41%), Gaps = 12/193 (6%)
Query: 2 LSCDGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGT-ARLKIKQV-TAEDE 59
+ G F CQ TG+P P + W + + +D+ A L+I+ + T DE
Sbjct: 43 IGVSGGVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESAGAVLRIQPLRTPRDE 102
Query: 60 GTYTCEASNCLGKAKSNACLVVYHTRRLSS--PGRQMAPTFYTYPFNKVVEEGENVTFKC 117
Y C A N +G+ +A L V +L S P M P KVVE T C
Sbjct: 103 NVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQL------KVVERTRTATMLC 156
Query: 118 AVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG- 176
A GNP P +W KD + PSA + K+ L+I+ D G Y N G
Sbjct: 157 AASGNPDPEITWFKDFLPVDPSAS-NGRIKQLRSGALQIESSEETDQGKYECVATNSAGV 215
Query: 177 RAEASARLEVITR 189
R + A L V R
Sbjct: 216 RYSSPANLYVRVR 228
Score = 68.9 bits (161), Expect = 1e-11
Identities = 49/179 (27%), Positives = 74/179 (41%), Gaps = 14/179 (7%)
Query: 8 TVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEAS 67
T C +GNPDP+I WF + A + L+I+ D+G Y C A+
Sbjct: 151 TATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEETDQGKYECVAT 210
Query: 68 NCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWA 127
N G S+ + RR+ AP F P + + G NV C G+P P+
Sbjct: 211 NSAGVRYSSPANLYVRVRRV-------APRFSILPMSHEIMPGGNVNITCVAVGSPMPYV 263
Query: 128 SWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W + +TP + V +LE+ +V +D Y + LG EA A++ V
Sbjct: 264 KWMQGAEDLTPEDDMPVGR-----NVLELTDV--KDSANYTCVAMSSLGVIEAVAQITV 315
Score = 46.8 bits (106), Expect = 6e-05
Identities = 29/122 (23%), Positives = 51/122 (41%), Gaps = 2/122 (1%)
Query: 96 PTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILE 155
P F P +++ G +F C G+P P +W+K G + T++ E +L
Sbjct: 33 PRFIKEPKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESAGAVLR 92
Query: 156 IDEV-SIEDVGIYRITVENELGRAEASARLEVITRSGKFYGGLRAYSASPRKCLSYRRRP 214
I + + D +Y +N +G A+L V+ R + G P+ + R R
Sbjct: 93 IQPLRTPRDENVYECVAQNSVGEITVHAKLTVL-REDQLPSGFPNIDMGPQLKVVERTRT 151
Query: 215 ST 216
+T
Sbjct: 152 AT 153
Score = 34.3 bits (75), Expect = 0.34
Identities = 21/76 (27%), Positives = 31/76 (40%), Gaps = 6/76 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G V C G+P P ++W AE D D R ++ +D YTC
Sbjct: 246 GGNVNITCVAVGSPMPYVKWMQGAE------DLTPEDDMPVGRNVLELTDVKDSANYTCV 299
Query: 66 ASNCLGKAKSNACLVV 81
A + LG ++ A + V
Sbjct: 300 AMSSLGVIEAVAQITV 315
>AL391824-1|CAI17865.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-268N14 on chromosome 1. ).
Length = 5635
Score = 75.4 bits (177), Expect = 1e-13
Identities = 55/183 (30%), Positives = 78/183 (42%), Gaps = 10/183 (5%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G V C+ +GNP P + W E+I + S+ DG+ L + E+ G Y C
Sbjct: 994 EGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGS--LYVVSPGGEESGEYVC 1051
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
A+N G AK L VY R+ R ++ P V GE VT C VK P
Sbjct: 1052 TATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQD---KPVEISVLAGEEVTLPCEVKSLPP 1108
Query: 125 PWASWDKDGSIITP-SARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
P +W K+ +I+P S R T ++I E D G+Y N G + +
Sbjct: 1109 PIITWAKETQLISPFSPRHTFLPSGS----MKITETRTSDSGMYLCVATNIAGNVTQAVK 1164
Query: 184 LEV 186
L V
Sbjct: 1165 LNV 1167
Score = 74.5 bits (175), Expect = 3e-13
Identities = 48/178 (26%), Positives = 75/178 (42%), Gaps = 13/178 (7%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
V +C G P+P I W + + G L+I + ED G YTC A+N
Sbjct: 1844 VALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATN 1902
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G+ + + L V+ L G+ + N+ V V +C GNP P +
Sbjct: 1903 AAGETQQHIQLHVHEPPSLEDAGKML---------NETVLVSNPVQLECKAAGNPVPVIT 1953
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KD +++ S +T + + I++I+ I D GIY+ N G E L+V
Sbjct: 1954 WYKDNRLLSGSTSMTFLNRGQ---IIDIESAQISDAGIYKCVAINSAGATELFYSLQV 2008
Score = 70.9 bits (166), Expect = 3e-12
Identities = 60/180 (33%), Positives = 80/180 (44%), Gaps = 20/180 (11%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+ + C+ TG P P + W +I A F+S +G + L I++V+ ED GTY C
Sbjct: 4274 GEQLRLSCKATGIPLPKLTWTFNNNIIP--AHFDSV--NGHSELVIERVSKEDSGTYVCT 4329
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFY-TYPFNKVVEEGENVTFKCAVKGNPS 124
A N +G K A VY + P P F YP N + G N C VKG+P+
Sbjct: 4330 AENSVGFVK--AIGFVY----VKEP-----PVFKGDYPSNWIEPLGGNAILNCEVKGDPT 4378
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
P W++ G I S RI ++ L I ED G Y NE G E S L
Sbjct: 4379 PTIQWNRKGVDIEISHRI----RQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSL 4434
Score = 68.5 bits (160), Expect = 2e-11
Identities = 47/179 (26%), Positives = 78/179 (43%), Gaps = 13/179 (7%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
++ EC+ G P P I W+ + I + ++ Y D L I + D TYTC +N
Sbjct: 1565 IKLECETRGLPMPAITWYKDGQPIMSSS--QALYIDKGQYLHIPRAQVSDSATYTCHVAN 1622
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G A+ + + VY + +A P NK V ++T +C GNPSP +
Sbjct: 1623 VAGTAEKSFHVDVYVPPMIEG---NLAT-----PLNKQVVIAHSLTLECKAAGNPSPILT 1674
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVI 187
W KDG + + I ++ + + I+ E+ D G Y + G E ++V+
Sbjct: 1675 WLKDGVPVKANDNIRIEAGGKKLEIMSAQEI---DRGQYICVATSVAGEKEIKYEVDVL 1730
Score = 67.7 bits (158), Expect = 3e-11
Identities = 43/182 (23%), Positives = 79/182 (43%), Gaps = 11/182 (6%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G+ + C+ +G P P++ W + + G +L+I D Y+C
Sbjct: 2210 EGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSC 2269
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
ASN G AK L VY +++ G ++P +V G++++ +C V+G P
Sbjct: 2270 VASNVAGTAKKEYNLQVYIRPTITNSG--------SHPTEIIVTRGKSISLECEVQGIPP 2321
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
P +W KDG + + + + ++ IL++ + + D G Y N G + L
Sbjct: 2322 PTVTWMKDGHPLIKAKGVEILDEG---HILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDL 2378
Query: 185 EV 186
V
Sbjct: 2379 SV 2380
Score = 66.5 bits (155), Expect = 7e-11
Identities = 53/174 (30%), Positives = 73/174 (41%), Gaps = 16/174 (9%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFE-SSYDD-GTARLKIKQVTAEDEGTYT 63
G V C V G P+P I+W + F SS T L I + A D+GTY
Sbjct: 807 GSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYI 866
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCA-VKGN 122
CEA N GK +S + V +AP P V EG+ +T C + GN
Sbjct: 867 CEAENQFGKIQSETTVTVTGL---------VAPLIGISPSVANVIEGQQLTLPCTLLAGN 917
Query: 123 PSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG 176
P P W K+ +++ + ITV+ L I+ V ++D G Y N G
Sbjct: 918 PIPERRWIKNSAMLLQNPYITVRSDGS----LHIERVQLQDGGEYTCVASNVAG 967
Score = 66.5 bits (155), Expect = 7e-11
Identities = 50/178 (28%), Positives = 71/178 (39%), Gaps = 13/178 (7%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
V ECQV G P PDI WF + + D D L +K D+G Y C SN
Sbjct: 1471 VALECQVKGTPFPDIHWFKDGKPL-FLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSN 1529
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
GK + L +Y + T + N +++ +C +G P P +
Sbjct: 1530 AAGKQAKDIKLTIYIPPSIKGGN---VTTDISVLINSLIK------LECETRGLPMPAIT 1580
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KDG I S++ +K + L I + D Y V N G AE S ++V
Sbjct: 1581 WYKDGQPIMSSSQALYIDKGQ---YLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDV 1635
Score = 65.7 bits (153), Expect = 1e-10
Identities = 46/178 (25%), Positives = 74/178 (41%), Gaps = 12/178 (6%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
+ C+V+G P PD+ W + I+ + + G L+I + D G YTC A N
Sbjct: 2982 ISLTCEVSGFPPPDLSWLKNEQPIK--LNTNTLIVPGGRTLQIIRAKVSDGGEYTCIAIN 3039
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G++K L VY + + V EG +V+ +C P P +
Sbjct: 3040 QAGESKKKFSLTVYVPPSIKDHDSESLSVVN-------VREGTSVSLECESNAVPPPVIT 3092
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W K+G +IT S + + + +L I + + D G Y N GR + + L V
Sbjct: 3093 WYKNGRMITESTHVEILADGQ---MLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNV 3147
Score = 65.3 bits (152), Expect = 2e-10
Identities = 52/182 (28%), Positives = 75/182 (41%), Gaps = 14/182 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
GD EC+ +G P P ++WF +R D LKI++ D G YTC
Sbjct: 716 GDITVMECKTSGIPPPQVKWFKGDLELRPSTFL--IIDPLLGLLKIQETQDLDAGDYTCV 773
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A N G+A L V SP P F P + +E G NVT C V+G P P
Sbjct: 774 AINEAGRATGKITLDV------GSP-----PVFIQEPADVSMEIGSNVTLPCYVQGYPEP 822
Query: 126 WASWDKDGSIITPSARITVKEKEEIMR-ILEIDEVSIEDVGIYRITVENELGRAEASARL 184
W + ++ S +V ++ L I + D G Y EN+ G+ ++ +
Sbjct: 823 TIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTV 882
Query: 185 EV 186
V
Sbjct: 883 TV 884
Score = 64.9 bits (151), Expect = 2e-10
Identities = 57/198 (28%), Positives = 82/198 (41%), Gaps = 19/198 (9%)
Query: 5 DGDTVEFECQV-TGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYT 63
+G + C + GNP P+ RW + ++ + + DG+ L I++V +D G YT
Sbjct: 903 EGQQLTLPCTLLAGNPIPERRWIKNSAMLLQ-NPYITVRSDGS--LHIERVQLQDGGEYT 959
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
C ASN G +VV H G+Q+ T EG VT C GNP
Sbjct: 960 CVASNVAGTNNKTTSVVV-HVLPTIQHGQQILSTI----------EGIPVTLPCKASGNP 1008
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
P W K G +I+ S + K L + E+ G Y T N G A+ +
Sbjct: 1009 KPSVIWSKKGELISTS---SAKFSAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKVQ 1065
Query: 184 LEVITRSGKFYGGLRAYS 201
L V R + +G R S
Sbjct: 1066 LTVYVRP-RVFGDQRGLS 1082
Score = 63.7 bits (148), Expect = 5e-10
Identities = 53/181 (29%), Positives = 70/181 (38%), Gaps = 17/181 (9%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G V C TG P P I W I + + DGT L IK +D G Y C
Sbjct: 626 GSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMT-SDGT--LFIKNAAPKDAGIYGCL 682
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
ASN G K N+ L R + AP +V G+ +C G P P
Sbjct: 683 ASNSAGTDKQNSTL-----RYIE------APKLMVVQSELLVALGDITVMECKTSGIPPP 731
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
W K + PS + + + ++ +L+I E D G Y NE GRA L+
Sbjct: 732 QVKWFKGDLELRPSTFLII---DPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLD 788
Query: 186 V 186
V
Sbjct: 789 V 789
Score = 63.7 bits (148), Expect = 5e-10
Identities = 47/178 (26%), Positives = 78/178 (43%), Gaps = 14/178 (7%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
+E +C VTG+P P I W ++I + F+ + +L I Q + G Y C A+N
Sbjct: 1752 LELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNG--RKLVIAQAQVSNTGLYRCMAAN 1809
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G K + V+ + S G +VV + + V +C G P+P +
Sbjct: 1810 TAGDHKKEFEVTVHVPPTIKSSGLS----------ERVVVKYKPVALQCIANGIPNPSIT 1859
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KD + +A+ +K + R+L+I + +ED G Y N G + +L V
Sbjct: 1860 WLKDDQPVN-TAQGNLKIQSS-GRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHV 1915
Score = 63.3 bits (147), Expect = 6e-10
Identities = 47/182 (25%), Positives = 73/182 (40%), Gaps = 13/182 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G ++ EC+V G P P + W + E D+G L++K + D G Y C
Sbjct: 2307 GKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEI-LDEGHI-LQLKNIHVSDTGRYVCV 2364
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A N G L V+ + R P N V E +V+ C G P P
Sbjct: 2365 AVNVAGMTDKKYDLSVHAPPSIIGNHRS--------PENISVVEKNSVSLTCEASGIPLP 2416
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
+W KDG ++ S + + ++R++ + ++ED G Y V N G L
Sbjct: 2417 SITWFKDGWPVSLSNSVRILSGGRMLRLM---QTTMEDAGQYTCVVRNAAGEERKIFGLS 2473
Query: 186 VI 187
V+
Sbjct: 2474 VL 2475
Score = 62.9 bits (146), Expect = 8e-10
Identities = 50/179 (27%), Positives = 71/179 (39%), Gaps = 13/179 (7%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
+EF C G P P I+W H + S +DGT L I VT D G Y C A N
Sbjct: 1284 IEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGTL-LVIASVTPYDNGEYICVAVN 1342
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G + L V H + Q+ N V + C V+G PSP
Sbjct: 1343 EAGTTERKYNLKV-HVPPVIKDKEQVT--------NVSVLLNQLTNLFCEVEGTPSPIIM 1393
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVI 187
W KD +T S+ I +I+++ + ED G Y N G ++ ++V+
Sbjct: 1394 WYKDNVQVTESSTIQTVNNGKILKLF---RATPEDAGRYSCKAINIAGTSQKYFNIDVL 1449
Score = 62.1 bits (144), Expect = 1e-09
Identities = 52/182 (28%), Positives = 71/182 (39%), Gaps = 12/182 (6%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G V+ C G P P I W + + S DGT L I Q T D G YTC
Sbjct: 1185 GQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGT--LSIDQATPSDAGIYTCV 1242
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A+N G ++ L V + + P + T +V + + F C KG P P
Sbjct: 1243 ATNIAGTDETEITLHVQEPPTVED----LEPPYNTTFQERVANQ--RIEFPCPAKGTPKP 1296
Query: 126 WASWDKDGSIIT-PSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
W +G +T I++ E +L I V+ D G Y NE G E L
Sbjct: 1297 TIKWLHNGRELTGREPGISILEDG---TLLVIASVTPYDNGEYICVAVNEAGTTERKYNL 1353
Query: 185 EV 186
+V
Sbjct: 1354 KV 1355
Score = 61.7 bits (143), Expect = 2e-09
Identities = 47/181 (25%), Positives = 68/181 (37%), Gaps = 16/181 (8%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+ V C+V P P I W ++I + + G+ +KI + D G Y C
Sbjct: 1094 GEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGS--MKITETRTSDSGMYLCV 1151
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A+N G L V+ + P P + V+ G+ V C +G P P
Sbjct: 1152 ATNIAGNVTQAVKLNVH-----------VPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLP 1200
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
+W K GS + V + L ID+ + D GIY N G E L
Sbjct: 1201 VITWSKGGSTMLVDGEHHVSNPD---GTLSIDQATPSDAGIYTCVATNIAGTDETEITLH 1257
Query: 186 V 186
V
Sbjct: 1258 V 1258
Score = 61.3 bits (142), Expect = 3e-09
Identities = 50/178 (28%), Positives = 64/178 (35%), Gaps = 10/178 (5%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
V C TG P P I W + I + E G ++L+I + D G YTC ASN
Sbjct: 3169 VTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASN 3228
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
GKA+ Y+ + P P + V GENV C G P+P
Sbjct: 3229 MEGKAQK------YYFLSIQVPPSVAGAEI---PSDVSVLLGENVELVCNANGIPTPLIQ 3279
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KDG I ++ L I D G Y N G + L V
Sbjct: 3280 WLKDGKPIASGETERIRVSAN-GSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNV 3336
Score = 60.1 bits (139), Expect = 6e-09
Identities = 48/168 (28%), Positives = 73/168 (43%), Gaps = 18/168 (10%)
Query: 13 CQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLGK 72
C G P P I W ++ + ++ G L ++ V ED G YTC A+N G+
Sbjct: 4190 CVADGIPTPAINWKKDNVLLANLLGKYTAEPYG--ELILENVVLEDSGFYTCVANNAAGE 4247
Query: 73 AKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKD 132
L V+ + PTF P + + +GE + C G P P +W +
Sbjct: 4248 DTHTVSLTVH-----------VLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFN 4296
Query: 133 GSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEA 180
+II P+ +V E++ I+ VS ED G Y T EN +G +A
Sbjct: 4297 NNII-PAHFDSVNGHSELV----IERVSKEDSGTYVCTAENSVGFVKA 4339
Score = 58.0 bits (134), Expect = 2e-08
Identities = 44/175 (25%), Positives = 75/175 (42%), Gaps = 15/175 (8%)
Query: 13 CQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLGK 72
C+V G P P I W+ + + + ++ ++G LK+ + T ED G Y+C+A N G
Sbjct: 1382 CEVEGTPSPIIMWYKDNVQVTESSTIQT-VNNGKI-LKLFRATPEDAGRYSCKAINIAGT 1439
Query: 73 AKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKD 132
++ Y + P + F P V +V +C VKG P P W KD
Sbjct: 1440 SQK------YFNIDVLVPPTIIGTNF---PNEVSVVLNRDVALECQVKGTPFPDIHWFKD 1490
Query: 133 GS-IITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
G + + + ++ + +L + D G Y+ TV N G+ +L +
Sbjct: 1491 GKPLFLGDPNVELLDRGQ---VLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTI 1542
Score = 57.6 bits (133), Expect = 3e-08
Identities = 49/176 (27%), Positives = 69/176 (39%), Gaps = 15/176 (8%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G +V EC+ P P I W+ +I + E D L IK+ D G Y C
Sbjct: 3073 EGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADG--QMLHIKKAEVSDTGQYVC 3130
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGEN-VTFKCAVKGNP 123
A N G+ N L VY + P R++ +VE N VT C G P
Sbjct: 3131 RAINVAGRDDKNFHLNVYVPPSIEGPEREV-----------IVETISNPVTLTCDATGIP 3179
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAE 179
P +W K+ I S + V+ + L+I D G Y N G+A+
Sbjct: 3180 PPTIAWLKNHKRIENSDSLEVRILSGGSK-LQIARSQHSDSGNYTCIASNMEGKAQ 3234
Score = 57.2 bits (132), Expect = 4e-08
Identities = 54/200 (27%), Positives = 74/200 (37%), Gaps = 29/200 (14%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSY---DDGTARLKIKQVTAEDEGTY 62
G C+V G+P P I+W R D E S+ G L I ED G Y
Sbjct: 4364 GGNAILNCEVKGDPTPTIQWN------RKGVDIEISHRIRQLGNGSLAIYGTVNEDAGDY 4417
Query: 63 TCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGN 122
TC A+N G + + L L SP P P V+ G + C G
Sbjct: 4418 TCVATNEAGVVERSMSLT------LQSP-----PIITLEPVETVINAGGKIILNCQATGE 4466
Query: 123 PSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASA 182
P P +W + G I+ R+ V L I + ED + N +G
Sbjct: 4467 PQPTITWSRQGHSISWDDRVNVLSNNS----LYIADAQKEDTSEFECVARNLMG--SVLV 4520
Query: 183 RLEVITRSGKFYGGLRAYSA 202
R+ VI + +GG +SA
Sbjct: 4521 RVPVIV---QVHGGFSQWSA 4537
Score = 56.8 bits (131), Expect = 6e-08
Identities = 48/178 (26%), Positives = 69/178 (38%), Gaps = 17/178 (9%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
+ C+ G P PDI W I + + G+ L+I V D G YTC A+N
Sbjct: 4096 ITLSCEADGLPPPDITWHKDGRAIVESIR-QRVLSSGS--LQIAFVQPGDAGHYTCMAAN 4152
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G + ++ L V+ R+ S YT V E C G P+P +
Sbjct: 4153 VAGSSSTSTKLTVHVPPRIRS-----TEGHYT------VNENSQAILPCVADGIPTPAIN 4201
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KD ++ A + K E L ++ V +ED G Y N G + L V
Sbjct: 4202 WKKDNVLL---ANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHTVSLTV 4256
Score = 56.4 bits (130), Expect = 7e-08
Identities = 46/181 (25%), Positives = 70/181 (38%), Gaps = 11/181 (6%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+ VE C G P P I+W + I + L I D G YTC
Sbjct: 3261 GENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCV 3320
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A+N G+ L VY T + + A T +V+ N+ +C G P P
Sbjct: 3321 ATNPAGEEDRIFNLNVYVTPTIRG-NKDEAEKLMT-----LVDTSINI--ECRATGTPPP 3372
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
+W K+G + S+ I + +++RI+ + DV +Y N G L+
Sbjct: 3373 QINWLKNGLPLPLSSHIRLLAAGQVIRIV---RAQVSDVAVYTCVASNRAGVDNKHYNLQ 3429
Query: 186 V 186
V
Sbjct: 3430 V 3430
Score = 56.4 bits (130), Expect = 7e-08
Identities = 49/174 (28%), Positives = 63/174 (36%), Gaps = 17/174 (9%)
Query: 13 CQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLGK 72
C+ TG P P I W + + G L+I + ED GTY C A N G
Sbjct: 4009 CEATGTPSPFITWQKEGINVNTSGRNHAVLPSGG--LQISRAVREDAGTYMCVAQNPAGT 4066
Query: 73 AKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKD 132
A L V Q+ P + V+ + +T C G P P +W KD
Sbjct: 4067 ALGKIKLNV-----------QVPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKD 4115
Query: 133 GSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
G I S R V L+I V D G Y N G + S +L V
Sbjct: 4116 GRAIVESIRQRVLSSGS----LQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTV 4165
Score = 56.0 bits (129), Expect = 1e-07
Identities = 45/180 (25%), Positives = 72/180 (40%), Gaps = 14/180 (7%)
Query: 8 TVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEAS 67
++ EC+ TG P P I W + + R+ QV+ D YTC AS
Sbjct: 3359 SINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVS--DVAVYTCVAS 3416
Query: 68 NCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWA 127
N G + L V+ + + M T V +G + + C G P+P
Sbjct: 3417 NRAGVDNKHYNLQVFAPPNMDN---SMGTEEIT------VLKGSSTSMACITDGTPAPSM 3467
Query: 128 SWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVI 187
+W +DG + A +TV ++++L+ + ED G Y NE G L+V+
Sbjct: 3468 AWLRDGQPLGLDAHLTVSTHGMVLQLLKAE---TEDSGKYTCIASNEAGEVSKHFILKVL 3524
Score = 55.6 bits (128), Expect = 1e-07
Identities = 48/183 (26%), Positives = 70/183 (38%), Gaps = 16/183 (8%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
VE CQ P P + W + S + + LKI+ +D G YTCEA+N
Sbjct: 2121 VELLCQSDAIPPPTLTWLKDGHPLLKKPGL--SISENRSVLKIEDAQVQDTGRYTCEATN 2178
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
GK + N + ++ + T V EG ++ C G P P
Sbjct: 2179 VAGKTEKNYNVNIWVPPNIGGSDELTQLT---------VIEGNLISLLCESSGIPPPNLI 2229
Query: 129 WDKDGS-IITPS-ARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W K GS ++T S R+ + R L+I D +Y N G A+ L+V
Sbjct: 2230 WKKKGSPVLTDSMGRVRILSGG---RQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQV 2286
Query: 187 ITR 189
R
Sbjct: 2287 YIR 2289
Score = 55.2 bits (127), Expect = 2e-07
Identities = 48/180 (26%), Positives = 66/180 (36%), Gaps = 14/180 (7%)
Query: 7 DTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEA 66
++V C+ +G P P I WF + G L++ Q T ED G YTC
Sbjct: 2402 NSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRIL--SGGRMLRLMQTTMEDAGQYTCVV 2459
Query: 67 SNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPW 126
N G+ + ++ L P T V+E ++VT C V GNP P
Sbjct: 2460 RNAAGEERK-----IFGLSVLVPPHIVGENTLEDVK----VKEKQSVTLTCEVTGNPVPE 2510
Query: 127 ASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
+W KDG P R L+I V + G Y + G S L V
Sbjct: 2511 ITWHKDGQ---PLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNV 2567
Score = 54.4 bits (125), Expect = 3e-07
Identities = 43/169 (25%), Positives = 67/169 (39%), Gaps = 11/169 (6%)
Query: 8 TVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEAS 67
+V C+VTGNP P+I W + +++ D G L+I V G YTC AS
Sbjct: 2496 SVTLTCEVTGNPVPEITWHKDGQPLQE--DEAHHIISGGRFLQITNVQVPHTGRYTCLAS 2553
Query: 68 NCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWA 127
+ G + L V+ + ++ G P T N + C P
Sbjct: 2554 SPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILN------SPTSLVCEAYSYPPATI 2607
Query: 128 SWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG 176
+W KDG+ + + I + ++IL E ++ G Y NE G
Sbjct: 2608 TWFKDGTPLESNRNIRILPGGRTLQILNAQE---DNAGRYSCVATNEAG 2653
Score = 54.4 bits (125), Expect = 3e-07
Identities = 43/173 (24%), Positives = 72/173 (41%), Gaps = 10/173 (5%)
Query: 7 DTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEA 66
+T+ EC+ P + W+ + ++ + + T L+IK+ D G YTC A
Sbjct: 2690 NTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHT--LQIKEAQISDTGRYTCVA 2747
Query: 67 SNCLGKAKSNACL---VVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
SN G+ + + + V ++L G M T V+ ++ C P
Sbjct: 2748 SNIAGEDELDFDVNIQVPPSFQKLWEIG-NMLDTGRNGEAKDVIINNP-ISLYCETNAAP 2805
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG 176
P +W KDG +T S ++ + R+L+I +ED G Y NE G
Sbjct: 2806 PPTLTWYKDGHPLTSSDKVLILPGG---RVLQIPRAKVEDAGRYTCVAVNEAG 2855
Score = 53.6 bits (123), Expect = 5e-07
Identities = 40/178 (22%), Positives = 66/178 (37%), Gaps = 15/178 (8%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
V EC+ G P P + W + ++ G L + D G YTC A N
Sbjct: 2029 VRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRI-LALTSAQISDTGRYTCVAVN 2087
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G+ + + L VY + P N V + V C P P +
Sbjct: 2088 AAGEKQRDIDLRVY-----------VPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLT 2136
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KDG + +++ E +L+I++ ++D G Y N G+ E + + +
Sbjct: 2137 WLKDGHPLLKKPGLSISENRS---VLKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNI 2191
Score = 52.8 bits (121), Expect = 9e-07
Identities = 46/179 (25%), Positives = 67/179 (37%), Gaps = 18/179 (10%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
V EC+ P P I W E ++ A G L+I D YTC ASN
Sbjct: 3639 VTLECKSDAVPPPVITWLRNGERLQ--ATPRVRILSGGRYLQINNADLGDTANYTCVASN 3696
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
GK L V + P P + V+ ++ +C +G P+P +
Sbjct: 3697 IAGKTTREFILTV-----------NVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRIT 3745
Query: 129 WDKDGSIITPS-ARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KDG+++ + AR ++ E L I + D G Y N G L+V
Sbjct: 3746 WRKDGAVLAGNHARYSILEN----GFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQV 3800
Score = 52.0 bits (119), Expect = 2e-06
Identities = 47/178 (26%), Positives = 68/178 (38%), Gaps = 12/178 (6%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
+ C+ P P + W+ + +D G L+I + ED G YTC A N
Sbjct: 2795 ISLYCETNAAPPPTLTWYKDGHPLTS-SDKVLILPGGRV-LQIPRAKVEDAGRYTCVAVN 2852
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G+ + Y R L P + A + P V ++ +C G+P+P S
Sbjct: 2853 EAGEDS-----LQYDVRVLVPPIIKGANS--DLPEEVTVLVNKSALIECLSSGSPAPRNS 2905
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KDG + RIL+I I D+G Y EN G A+ L V
Sbjct: 2906 WQKDGQPLLEDDHHKFLSNG---RILQILNTQITDIGRYVCVAENTAGSAKKYFNLNV 2960
Score = 50.8 bits (116), Expect = 4e-06
Identities = 45/179 (25%), Positives = 68/179 (37%), Gaps = 17/179 (9%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
V+ EC+ GNP P I W+ ++ ++ + + I+ D G Y C A N
Sbjct: 1938 VQLECKAAGNPVPVITWYKDNRLLSGSTSM--TFLNRGQIIDIESAQISDAGIYKCVAIN 1995
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G + L V+ +S +A V V +C +G P+P +
Sbjct: 1996 SAGATELFYSLQVHVAPSISGSNNMVA-----------VVVNNPVRLECEARGIPAPSLT 2044
Query: 129 WDKDGSIITP-SARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KDGS ++ S + V RIL + I D G Y N G + L V
Sbjct: 2045 WLKDGSPVSSFSNGLQVLSGG---RILALTSAQISDTGRYTCVAVNAAGEKQRDIDLRV 2100
Score = 48.8 bits (111), Expect = 1e-05
Identities = 40/171 (23%), Positives = 68/171 (39%), Gaps = 18/171 (10%)
Query: 8 TVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEAS 67
++ EC+ GNP P + W ++ A+ + G +L+I D G Y C A+
Sbjct: 1658 SLTLECKAAGNPSPILTWLKDGVPVK--ANDNIRIEAGGKKLEIMSAQEIDRGQYICVAT 1715
Query: 68 NCLGKAKSNACLVVYHTRRLSSPGRQMA--PTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
+ G+ + + Y L P + +++ N ++E C V G+P P
Sbjct: 1716 SVAGEKE-----IKYEVDVLVPPAIEGGDETSYFIVMVNNLLE------LDCHVTGSPPP 1764
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG 176
W KDG +I + R L I + + + G+YR N G
Sbjct: 1765 TIMWLKDGQLIDERDGFKILLNG---RKLVIAQAQVSNTGLYRCMAANTAG 1812
Score = 47.6 bits (108), Expect = 3e-05
Identities = 43/174 (24%), Positives = 57/174 (32%), Gaps = 16/174 (9%)
Query: 13 CQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLGK 72
C +G P P I W + D G + Q+ G YTC A N G
Sbjct: 3918 CTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQLN--HAGRYTCVARNAAGS 3975
Query: 73 AKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKD 132
A + L V+ P P V + C G PSP+ +W K+
Sbjct: 3976 AHRHVTLHVHEP-----------PVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKE 4024
Query: 133 GSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
G + S R L+I ED G Y +N G A +L V
Sbjct: 4025 GINVNTSGR---NHAVLPSGGLQISRAVREDAGTYMCVAQNPAGTALGKIKLNV 4075
Score = 47.2 bits (107), Expect = 4e-05
Identities = 48/180 (26%), Positives = 67/180 (37%), Gaps = 24/180 (13%)
Query: 12 ECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLG 71
EC G P P I W V+ S ++G ++ VT D G Y C A+N G
Sbjct: 3733 ECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLHIQSAHVT--DTGRYLCMATNAAG 3790
Query: 72 KAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDK 131
+ L V H +PG P N V T C G P P +W K
Sbjct: 3791 TDRRRIDLQV-HVPPSIAPG----------PTNMTVIVNVQTTLACEATGIPKPSINWRK 3839
Query: 132 DGSIITPSARITVKEKEEIMRILE-----IDEVSIEDVGIYRITVENELGRAEASARLEV 186
+G + + V + + R+L I S++D Y TV N G + + L V
Sbjct: 3840 NGHL------LNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGDDKRTVDLTV 3893
Score = 46.8 bits (106), Expect = 6e-05
Identities = 38/171 (22%), Positives = 63/171 (36%), Gaps = 14/171 (8%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G + C G P P + W + + D + L++ + ED G YTC
Sbjct: 3450 GSSTSMACITDGTPAPSMAWLRDGQPLG--LDAHLTVSTHGMVLQLLKAETEDSGKYTCI 3507
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
ASN G+ + L V ++ + +V +T C G P+P
Sbjct: 3508 ASNEAGEVSKHFILKVLEPPHINGSEEHEE-------ISVIVNNPLELT--CIASGIPAP 3558
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG 176
+W KDG + + ++ E++R I +ED G Y + G
Sbjct: 3559 KMTWMKDGRPLPQTDQVQTLGGGEVLR---ISTAQVEDTGRYTCLASSPAG 3606
Score = 42.3 bits (95), Expect = 0.001
Identities = 41/176 (23%), Positives = 60/176 (34%), Gaps = 18/176 (10%)
Query: 13 CQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLGK 72
C+ TG P P I W ++ + S + L I + +D TY C +N G
Sbjct: 3825 CEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGD 3884
Query: 73 AKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKD 132
K L V Q+ P+ P + +V + C G P P W K+
Sbjct: 3885 DKRTVDLTV-----------QVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKN 3933
Query: 133 GSIITPSARITVKEKEEIMR--ILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
G + P + I+ +EI + G Y N G A L V
Sbjct: 3934 GIRLLPRG-----DGYRILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHV 3984
Score = 41.9 bits (94), Expect = 0.002
Identities = 38/167 (22%), Positives = 59/167 (35%), Gaps = 8/167 (4%)
Query: 13 CQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLGK 72
C+ P I WF + + G L+I ++ G Y+C A+N G+
Sbjct: 2597 CEAYSYPPATITWFKDGTPLESNRNIRIL--PGGRTLQILNAQEDNAGRYSCVATNEAGE 2654
Query: 73 AKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKD 132
+ + VY + + G P P ++ +T +C PS SW KD
Sbjct: 2655 MIKHYEVKVY-IPPIINKGDLWGPGLS--PKEVKIKVNNTLTLECEAYAIPSASLSWYKD 2711
Query: 133 GSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAE 179
G + + + L+I E I D G Y N G E
Sbjct: 2712 GQPLKSDDHVNIAANG---HTLQIKEAQISDTGRYTCVASNIAGEDE 2755
Score = 40.7 bits (91), Expect = 0.004
Identities = 36/169 (21%), Positives = 61/169 (36%), Gaps = 14/169 (8%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
+E C +G P P + W + ++ G L+I ED G YTC AS+
Sbjct: 3546 LELTCIASGIPAPKMTWMKDGRPLPQTDQVQTL--GGGEVLRISTAQVEDTGRYTCLASS 3603
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G + V+ ++ P + V VT +C P P +
Sbjct: 3604 PAGDDDKEYLVRVHVPPNIAGTDE---------PRDITVLRNRQVTLECKSDAVPPPVIT 3654
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGR 177
W ++G + + R+ + R L+I+ + D Y N G+
Sbjct: 3655 WLRNGERLQATPRVRILSGG---RYLQINNADLGDTANYTCVASNIAGK 3700
Score = 40.3 bits (90), Expect = 0.005
Identities = 34/139 (24%), Positives = 52/139 (37%), Gaps = 15/139 (10%)
Query: 49 LKIKQVTAEDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVE 108
L++K V D G Y C S+ G + ++ L V Q P P N+
Sbjct: 576 LELKSVKFNDAGEYHCMVSSEGGSSAASVFLTV-----------QEPPKVTVMPKNQSFT 624
Query: 109 EGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYR 168
G V+ C+ G P P +W + I S R + + I + +D GIY
Sbjct: 625 GGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGTLF----IKNAAPKDAGIYG 680
Query: 169 ITVENELGRAEASARLEVI 187
N G + ++ L I
Sbjct: 681 CLASNSAGTDKQNSTLRYI 699
Score = 39.9 bits (89), Expect = 0.007
Identities = 43/175 (24%), Positives = 63/175 (36%), Gaps = 15/175 (8%)
Query: 12 ECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLG 71
EC +G+P P W + + + D +G L+I D G Y C A N G
Sbjct: 2893 ECLSSGSPAPRNSWQKDGQPLLE-DDHHKFLSNGRI-LQILNTQITDIGRYVCVAENTAG 2950
Query: 72 KAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDK 131
AK L V+ + P + N V ++ C V G P P SW K
Sbjct: 2951 SAKKYFNLNVHVPPSVIGPKSE----------NLTVVVNNFISLTCEVSGFPPPDLSWLK 3000
Query: 132 DGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
+ I + + R L+I + D G Y N+ G ++ L V
Sbjct: 3001 NEQPIKLNTNTLIVPGG---RTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTV 3052
Score = 39.1 bits (87), Expect = 0.012
Identities = 35/144 (24%), Positives = 53/144 (36%), Gaps = 13/144 (9%)
Query: 43 DDGTARLKIKQVTAEDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYP 102
+ + L I +VT DEG Y C A + G ++ V S P P P
Sbjct: 478 ESASVNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDV------SEP-----PPVIQVP 526
Query: 103 FNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIE 162
N V GE C + +W ++ + + ++ + LE+ V
Sbjct: 527 NNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLS--LELKSVKFN 584
Query: 163 DVGIYRITVENELGRAEASARLEV 186
D G Y V +E G + AS L V
Sbjct: 585 DAGEYHCMVSSEGGSSAASVFLTV 608
>AL135797-1|CAI17871.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-77J13 on chromosome 1. ).
Length = 5635
Score = 75.4 bits (177), Expect = 1e-13
Identities = 55/183 (30%), Positives = 78/183 (42%), Gaps = 10/183 (5%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G V C+ +GNP P + W E+I + S+ DG+ L + E+ G Y C
Sbjct: 994 EGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGS--LYVVSPGGEESGEYVC 1051
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
A+N G AK L VY R+ R ++ P V GE VT C VK P
Sbjct: 1052 TATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQD---KPVEISVLAGEEVTLPCEVKSLPP 1108
Query: 125 PWASWDKDGSIITP-SARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
P +W K+ +I+P S R T ++I E D G+Y N G + +
Sbjct: 1109 PIITWAKETQLISPFSPRHTFLPSGS----MKITETRTSDSGMYLCVATNIAGNVTQAVK 1164
Query: 184 LEV 186
L V
Sbjct: 1165 LNV 1167
Score = 74.5 bits (175), Expect = 3e-13
Identities = 48/178 (26%), Positives = 75/178 (42%), Gaps = 13/178 (7%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
V +C G P+P I W + + G L+I + ED G YTC A+N
Sbjct: 1844 VALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATN 1902
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G+ + + L V+ L G+ + N+ V V +C GNP P +
Sbjct: 1903 AAGETQQHIQLHVHEPPSLEDAGKML---------NETVLVSNPVQLECKAAGNPVPVIT 1953
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KD +++ S +T + + I++I+ I D GIY+ N G E L+V
Sbjct: 1954 WYKDNRLLSGSTSMTFLNRGQ---IIDIESAQISDAGIYKCVAINSAGATELFYSLQV 2008
Score = 70.9 bits (166), Expect = 3e-12
Identities = 60/180 (33%), Positives = 80/180 (44%), Gaps = 20/180 (11%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+ + C+ TG P P + W +I A F+S +G + L I++V+ ED GTY C
Sbjct: 4274 GEQLRLSCKATGIPLPKLTWTFNNNIIP--AHFDSV--NGHSELVIERVSKEDSGTYVCT 4329
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFY-TYPFNKVVEEGENVTFKCAVKGNPS 124
A N +G K A VY + P P F YP N + G N C VKG+P+
Sbjct: 4330 AENSVGFVK--AIGFVY----VKEP-----PVFKGDYPSNWIEPLGGNAILNCEVKGDPT 4378
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
P W++ G I S RI ++ L I ED G Y NE G E S L
Sbjct: 4379 PTIQWNRKGVDIEISHRI----RQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSL 4434
Score = 68.5 bits (160), Expect = 2e-11
Identities = 47/179 (26%), Positives = 78/179 (43%), Gaps = 13/179 (7%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
++ EC+ G P P I W+ + I + ++ Y D L I + D TYTC +N
Sbjct: 1565 IKLECETRGLPMPAITWYKDGQPIMSSS--QALYIDKGQYLHIPRAQVSDSATYTCHVAN 1622
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G A+ + + VY + +A P NK V ++T +C GNPSP +
Sbjct: 1623 VAGTAEKSFHVDVYVPPMIEG---NLAT-----PLNKQVVIAHSLTLECKAAGNPSPILT 1674
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVI 187
W KDG + + I ++ + + I+ E+ D G Y + G E ++V+
Sbjct: 1675 WLKDGVPVKANDNIRIEAGGKKLEIMSAQEI---DRGQYICVATSVAGEKEIKYEVDVL 1730
Score = 67.7 bits (158), Expect = 3e-11
Identities = 43/182 (23%), Positives = 79/182 (43%), Gaps = 11/182 (6%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G+ + C+ +G P P++ W + + G +L+I D Y+C
Sbjct: 2210 EGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSC 2269
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
ASN G AK L VY +++ G ++P +V G++++ +C V+G P
Sbjct: 2270 VASNVAGTAKKEYNLQVYIRPTITNSG--------SHPTEIIVTRGKSISLECEVQGIPP 2321
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
P +W KDG + + + + ++ IL++ + + D G Y N G + L
Sbjct: 2322 PTVTWMKDGHPLIKAKGVEILDEG---HILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDL 2378
Query: 185 EV 186
V
Sbjct: 2379 SV 2380
Score = 66.5 bits (155), Expect = 7e-11
Identities = 53/174 (30%), Positives = 73/174 (41%), Gaps = 16/174 (9%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFE-SSYDD-GTARLKIKQVTAEDEGTYT 63
G V C V G P+P I+W + F SS T L I + A D+GTY
Sbjct: 807 GSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYI 866
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCA-VKGN 122
CEA N GK +S + V +AP P V EG+ +T C + GN
Sbjct: 867 CEAENQFGKIQSETTVTVTGL---------VAPLIGISPSVANVIEGQQLTLPCTLLAGN 917
Query: 123 PSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG 176
P P W K+ +++ + ITV+ L I+ V ++D G Y N G
Sbjct: 918 PIPERRWIKNSAMLLQNPYITVRSDGS----LHIERVQLQDGGEYTCVASNVAG 967
Score = 66.5 bits (155), Expect = 7e-11
Identities = 50/178 (28%), Positives = 71/178 (39%), Gaps = 13/178 (7%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
V ECQV G P PDI WF + + D D L +K D+G Y C SN
Sbjct: 1471 VALECQVKGTPFPDIHWFKDGKPL-FLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSN 1529
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
GK + L +Y + T + N +++ +C +G P P +
Sbjct: 1530 AAGKQAKDIKLTIYIPPSIKGGN---VTTDISVLINSLIK------LECETRGLPMPAIT 1580
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KDG I S++ +K + L I + D Y V N G AE S ++V
Sbjct: 1581 WYKDGQPIMSSSQALYIDKGQ---YLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDV 1635
Score = 65.7 bits (153), Expect = 1e-10
Identities = 46/178 (25%), Positives = 74/178 (41%), Gaps = 12/178 (6%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
+ C+V+G P PD+ W + I+ + + G L+I + D G YTC A N
Sbjct: 2982 ISLTCEVSGFPPPDLSWLKNEQPIK--LNTNTLIVPGGRTLQIIRAKVSDGGEYTCIAIN 3039
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G++K L VY + + V EG +V+ +C P P +
Sbjct: 3040 QAGESKKKFSLTVYVPPSIKDHDSESLSVVN-------VREGTSVSLECESNAVPPPVIT 3092
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W K+G +IT S + + + +L I + + D G Y N GR + + L V
Sbjct: 3093 WYKNGRMITESTHVEILADGQ---MLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNV 3147
Score = 65.3 bits (152), Expect = 2e-10
Identities = 52/182 (28%), Positives = 75/182 (41%), Gaps = 14/182 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
GD EC+ +G P P ++WF +R D LKI++ D G YTC
Sbjct: 716 GDITVMECKTSGIPPPQVKWFKGDLELRPSTFL--IIDPLLGLLKIQETQDLDAGDYTCV 773
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A N G+A L V SP P F P + +E G NVT C V+G P P
Sbjct: 774 AINEAGRATGKITLDV------GSP-----PVFIQEPADVSMEIGSNVTLPCYVQGYPEP 822
Query: 126 WASWDKDGSIITPSARITVKEKEEIMR-ILEIDEVSIEDVGIYRITVENELGRAEASARL 184
W + ++ S +V ++ L I + D G Y EN+ G+ ++ +
Sbjct: 823 TIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTV 882
Query: 185 EV 186
V
Sbjct: 883 TV 884
Score = 64.9 bits (151), Expect = 2e-10
Identities = 57/198 (28%), Positives = 82/198 (41%), Gaps = 19/198 (9%)
Query: 5 DGDTVEFECQV-TGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYT 63
+G + C + GNP P+ RW + ++ + + DG+ L I++V +D G YT
Sbjct: 903 EGQQLTLPCTLLAGNPIPERRWIKNSAMLLQ-NPYITVRSDGS--LHIERVQLQDGGEYT 959
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
C ASN G +VV H G+Q+ T EG VT C GNP
Sbjct: 960 CVASNVAGTNNKTTSVVV-HVLPTIQHGQQILSTI----------EGIPVTLPCKASGNP 1008
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
P W K G +I+ S + K L + E+ G Y T N G A+ +
Sbjct: 1009 KPSVIWSKKGELISTS---SAKFSAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKVQ 1065
Query: 184 LEVITRSGKFYGGLRAYS 201
L V R + +G R S
Sbjct: 1066 LTVYVRP-RVFGDQRGLS 1082
Score = 63.7 bits (148), Expect = 5e-10
Identities = 53/181 (29%), Positives = 70/181 (38%), Gaps = 17/181 (9%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G V C TG P P I W I + + DGT L IK +D G Y C
Sbjct: 626 GSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMT-SDGT--LFIKNAAPKDAGIYGCL 682
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
ASN G K N+ L R + AP +V G+ +C G P P
Sbjct: 683 ASNSAGTDKQNSTL-----RYIE------APKLMVVQSELLVALGDITVMECKTSGIPPP 731
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
W K + PS + + + ++ +L+I E D G Y NE GRA L+
Sbjct: 732 QVKWFKGDLELRPSTFLII---DPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLD 788
Query: 186 V 186
V
Sbjct: 789 V 789
Score = 63.7 bits (148), Expect = 5e-10
Identities = 47/178 (26%), Positives = 78/178 (43%), Gaps = 14/178 (7%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
+E +C VTG+P P I W ++I + F+ + +L I Q + G Y C A+N
Sbjct: 1752 LELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNG--RKLVIAQAQVSNTGLYRCMAAN 1809
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G K + V+ + S G +VV + + V +C G P+P +
Sbjct: 1810 TAGDHKKEFEVTVHVPPTIKSSGLS----------ERVVVKYKPVALQCIANGIPNPSIT 1859
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KD + +A+ +K + R+L+I + +ED G Y N G + +L V
Sbjct: 1860 WLKDDQPVN-TAQGNLKIQSS-GRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHV 1915
Score = 63.3 bits (147), Expect = 6e-10
Identities = 47/182 (25%), Positives = 73/182 (40%), Gaps = 13/182 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G ++ EC+V G P P + W + E D+G L++K + D G Y C
Sbjct: 2307 GKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEI-LDEGHI-LQLKNIHVSDTGRYVCV 2364
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A N G L V+ + R P N V E +V+ C G P P
Sbjct: 2365 AVNVAGMTDKKYDLSVHAPPSIIGNHRS--------PENISVVEKNSVSLTCEASGIPLP 2416
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
+W KDG ++ S + + ++R++ + ++ED G Y V N G L
Sbjct: 2417 SITWFKDGWPVSLSNSVRILSGGRMLRLM---QTTMEDAGQYTCVVRNAAGEERKIFGLS 2473
Query: 186 VI 187
V+
Sbjct: 2474 VL 2475
Score = 62.9 bits (146), Expect = 8e-10
Identities = 50/179 (27%), Positives = 71/179 (39%), Gaps = 13/179 (7%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
+EF C G P P I+W H + S +DGT L I VT D G Y C A N
Sbjct: 1284 IEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGTL-LVIASVTPYDNGEYICVAVN 1342
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G + L V H + Q+ N V + C V+G PSP
Sbjct: 1343 EAGTTERKYNLKV-HVPPVIKDKEQVT--------NVSVLLNQLTNLFCEVEGTPSPIIM 1393
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVI 187
W KD +T S+ I +I+++ + ED G Y N G ++ ++V+
Sbjct: 1394 WYKDNVQVTESSTIQTVNNGKILKLF---RATPEDAGRYSCKAINIAGTSQKYFNIDVL 1449
Score = 62.1 bits (144), Expect = 1e-09
Identities = 52/182 (28%), Positives = 71/182 (39%), Gaps = 12/182 (6%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G V+ C G P P I W + + S DGT L I Q T D G YTC
Sbjct: 1185 GQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGT--LSIDQATPSDAGIYTCV 1242
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A+N G ++ L V + + P + T +V + + F C KG P P
Sbjct: 1243 ATNIAGTDETEITLHVQEPPTVED----LEPPYNTTFQERVANQ--RIEFPCPAKGTPKP 1296
Query: 126 WASWDKDGSIIT-PSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
W +G +T I++ E +L I V+ D G Y NE G E L
Sbjct: 1297 TIKWLHNGRELTGREPGISILEDG---TLLVIASVTPYDNGEYICVAVNEAGTTERKYNL 1353
Query: 185 EV 186
+V
Sbjct: 1354 KV 1355
Score = 61.7 bits (143), Expect = 2e-09
Identities = 47/181 (25%), Positives = 68/181 (37%), Gaps = 16/181 (8%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+ V C+V P P I W ++I + + G+ +KI + D G Y C
Sbjct: 1094 GEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGS--MKITETRTSDSGMYLCV 1151
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A+N G L V+ + P P + V+ G+ V C +G P P
Sbjct: 1152 ATNIAGNVTQAVKLNVH-----------VPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLP 1200
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
+W K GS + V + L ID+ + D GIY N G E L
Sbjct: 1201 VITWSKGGSTMLVDGEHHVSNPD---GTLSIDQATPSDAGIYTCVATNIAGTDETEITLH 1257
Query: 186 V 186
V
Sbjct: 1258 V 1258
Score = 61.3 bits (142), Expect = 3e-09
Identities = 50/178 (28%), Positives = 64/178 (35%), Gaps = 10/178 (5%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
V C TG P P I W + I + E G ++L+I + D G YTC ASN
Sbjct: 3169 VTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASN 3228
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
GKA+ Y+ + P P + V GENV C G P+P
Sbjct: 3229 MEGKAQK------YYFLSIQVPPSVAGAEI---PSDVSVLLGENVELVCNANGIPTPLIQ 3279
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KDG I ++ L I D G Y N G + L V
Sbjct: 3280 WLKDGKPIASGETERIRVSAN-GSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNV 3336
Score = 60.1 bits (139), Expect = 6e-09
Identities = 48/168 (28%), Positives = 73/168 (43%), Gaps = 18/168 (10%)
Query: 13 CQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLGK 72
C G P P I W ++ + ++ G L ++ V ED G YTC A+N G+
Sbjct: 4190 CVADGIPTPAINWKKDNVLLANLLGKYTAEPYG--ELILENVVLEDSGFYTCVANNAAGE 4247
Query: 73 AKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKD 132
L V+ + PTF P + + +GE + C G P P +W +
Sbjct: 4248 DTHTVSLTVH-----------VLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFN 4296
Query: 133 GSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEA 180
+II P+ +V E++ I+ VS ED G Y T EN +G +A
Sbjct: 4297 NNII-PAHFDSVNGHSELV----IERVSKEDSGTYVCTAENSVGFVKA 4339
Score = 58.0 bits (134), Expect = 2e-08
Identities = 44/175 (25%), Positives = 75/175 (42%), Gaps = 15/175 (8%)
Query: 13 CQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLGK 72
C+V G P P I W+ + + + ++ ++G LK+ + T ED G Y+C+A N G
Sbjct: 1382 CEVEGTPSPIIMWYKDNVQVTESSTIQT-VNNGKI-LKLFRATPEDAGRYSCKAINIAGT 1439
Query: 73 AKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKD 132
++ Y + P + F P V +V +C VKG P P W KD
Sbjct: 1440 SQK------YFNIDVLVPPTIIGTNF---PNEVSVVLNRDVALECQVKGTPFPDIHWFKD 1490
Query: 133 GS-IITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
G + + + ++ + +L + D G Y+ TV N G+ +L +
Sbjct: 1491 GKPLFLGDPNVELLDRGQ---VLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTI 1542
Score = 57.6 bits (133), Expect = 3e-08
Identities = 49/176 (27%), Positives = 69/176 (39%), Gaps = 15/176 (8%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G +V EC+ P P I W+ +I + E D L IK+ D G Y C
Sbjct: 3073 EGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADG--QMLHIKKAEVSDTGQYVC 3130
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGEN-VTFKCAVKGNP 123
A N G+ N L VY + P R++ +VE N VT C G P
Sbjct: 3131 RAINVAGRDDKNFHLNVYVPPSIEGPEREV-----------IVETISNPVTLTCDATGIP 3179
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAE 179
P +W K+ I S + V+ + L+I D G Y N G+A+
Sbjct: 3180 PPTIAWLKNHKRIENSDSLEVRILSGGSK-LQIARSQHSDSGNYTCIASNMEGKAQ 3234
Score = 57.2 bits (132), Expect = 4e-08
Identities = 54/200 (27%), Positives = 74/200 (37%), Gaps = 29/200 (14%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSY---DDGTARLKIKQVTAEDEGTY 62
G C+V G+P P I+W R D E S+ G L I ED G Y
Sbjct: 4364 GGNAILNCEVKGDPTPTIQWN------RKGVDIEISHRIRQLGNGSLAIYGTVNEDAGDY 4417
Query: 63 TCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGN 122
TC A+N G + + L L SP P P V+ G + C G
Sbjct: 4418 TCVATNEAGVVERSMSLT------LQSP-----PIITLEPVETVINAGGKIILNCQATGE 4466
Query: 123 PSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASA 182
P P +W + G I+ R+ V L I + ED + N +G
Sbjct: 4467 PQPTITWSRQGHSISWDDRVNVLSNNS----LYIADAQKEDTSEFECVARNLMG--SVLV 4520
Query: 183 RLEVITRSGKFYGGLRAYSA 202
R+ VI + +GG +SA
Sbjct: 4521 RVPVIV---QVHGGFSQWSA 4537
Score = 56.8 bits (131), Expect = 6e-08
Identities = 48/178 (26%), Positives = 69/178 (38%), Gaps = 17/178 (9%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
+ C+ G P PDI W I + + G+ L+I V D G YTC A+N
Sbjct: 4096 ITLSCEADGLPPPDITWHKDGRAIVESIR-QRVLSSGS--LQIAFVQPGDAGHYTCMAAN 4152
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G + ++ L V+ R+ S YT V E C G P+P +
Sbjct: 4153 VAGSSSTSTKLTVHVPPRIRS-----TEGHYT------VNENSQAILPCVADGIPTPAIN 4201
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KD ++ A + K E L ++ V +ED G Y N G + L V
Sbjct: 4202 WKKDNVLL---ANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHTVSLTV 4256
Score = 56.4 bits (130), Expect = 7e-08
Identities = 46/181 (25%), Positives = 70/181 (38%), Gaps = 11/181 (6%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+ VE C G P P I+W + I + L I D G YTC
Sbjct: 3261 GENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCV 3320
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A+N G+ L VY T + + A T +V+ N+ +C G P P
Sbjct: 3321 ATNPAGEEDRIFNLNVYVTPTIRG-NKDEAEKLMT-----LVDTSINI--ECRATGTPPP 3372
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
+W K+G + S+ I + +++RI+ + DV +Y N G L+
Sbjct: 3373 QINWLKNGLPLPLSSHIRLLAAGQVIRIV---RAQVSDVAVYTCVASNRAGVDNKHYNLQ 3429
Query: 186 V 186
V
Sbjct: 3430 V 3430
Score = 56.4 bits (130), Expect = 7e-08
Identities = 49/174 (28%), Positives = 63/174 (36%), Gaps = 17/174 (9%)
Query: 13 CQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLGK 72
C+ TG P P I W + + G L+I + ED GTY C A N G
Sbjct: 4009 CEATGTPSPFITWQKEGINVNTSGRNHAVLPSGG--LQISRAVREDAGTYMCVAQNPAGT 4066
Query: 73 AKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKD 132
A L V Q+ P + V+ + +T C G P P +W KD
Sbjct: 4067 ALGKIKLNV-----------QVPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKD 4115
Query: 133 GSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
G I S R V L+I V D G Y N G + S +L V
Sbjct: 4116 GRAIVESIRQRVLSSGS----LQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTV 4165
Score = 56.0 bits (129), Expect = 1e-07
Identities = 45/180 (25%), Positives = 72/180 (40%), Gaps = 14/180 (7%)
Query: 8 TVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEAS 67
++ EC+ TG P P I W + + R+ QV+ D YTC AS
Sbjct: 3359 SINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVS--DVAVYTCVAS 3416
Query: 68 NCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWA 127
N G + L V+ + + M T V +G + + C G P+P
Sbjct: 3417 NRAGVDNKHYNLQVFAPPNMDN---SMGTEEIT------VLKGSSTSMACITDGTPAPSM 3467
Query: 128 SWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVI 187
+W +DG + A +TV ++++L+ + ED G Y NE G L+V+
Sbjct: 3468 AWLRDGQPLGLDAHLTVSTHGMVLQLLKAE---TEDSGKYTCIASNEAGEVSKHFILKVL 3524
Score = 55.6 bits (128), Expect = 1e-07
Identities = 48/183 (26%), Positives = 70/183 (38%), Gaps = 16/183 (8%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
VE CQ P P + W + S + + LKI+ +D G YTCEA+N
Sbjct: 2121 VELLCQSDAIPPPTLTWLKDGHPLLKKPGL--SISENRSVLKIEDAQVQDTGRYTCEATN 2178
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
GK + N + ++ + T V EG ++ C G P P
Sbjct: 2179 VAGKTEKNYNVNIWVPPNIGGSDELTQLT---------VIEGNLISLLCESSGIPPPNLI 2229
Query: 129 WDKDGS-IITPS-ARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W K GS ++T S R+ + R L+I D +Y N G A+ L+V
Sbjct: 2230 WKKKGSPVLTDSMGRVRILSGG---RQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQV 2286
Query: 187 ITR 189
R
Sbjct: 2287 YIR 2289
Score = 55.2 bits (127), Expect = 2e-07
Identities = 48/180 (26%), Positives = 66/180 (36%), Gaps = 14/180 (7%)
Query: 7 DTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEA 66
++V C+ +G P P I WF + G L++ Q T ED G YTC
Sbjct: 2402 NSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRIL--SGGRMLRLMQTTMEDAGQYTCVV 2459
Query: 67 SNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPW 126
N G+ + ++ L P T V+E ++VT C V GNP P
Sbjct: 2460 RNAAGEERK-----IFGLSVLVPPHIVGENTLEDVK----VKEKQSVTLTCEVTGNPVPE 2510
Query: 127 ASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
+W KDG P R L+I V + G Y + G S L V
Sbjct: 2511 ITWHKDGQ---PLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNV 2567
Score = 54.4 bits (125), Expect = 3e-07
Identities = 43/169 (25%), Positives = 67/169 (39%), Gaps = 11/169 (6%)
Query: 8 TVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEAS 67
+V C+VTGNP P+I W + +++ D G L+I V G YTC AS
Sbjct: 2496 SVTLTCEVTGNPVPEITWHKDGQPLQE--DEAHHIISGGRFLQITNVQVPHTGRYTCLAS 2553
Query: 68 NCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWA 127
+ G + L V+ + ++ G P T N + C P
Sbjct: 2554 SPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILN------SPTSLVCEAYSYPPATI 2607
Query: 128 SWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG 176
+W KDG+ + + I + ++IL E ++ G Y NE G
Sbjct: 2608 TWFKDGTPLESNRNIRILPGGRTLQILNAQE---DNAGRYSCVATNEAG 2653
Score = 54.4 bits (125), Expect = 3e-07
Identities = 43/173 (24%), Positives = 72/173 (41%), Gaps = 10/173 (5%)
Query: 7 DTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEA 66
+T+ EC+ P + W+ + ++ + + T L+IK+ D G YTC A
Sbjct: 2690 NTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHT--LQIKEAQISDTGRYTCVA 2747
Query: 67 SNCLGKAKSNACL---VVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
SN G+ + + + V ++L G M T V+ ++ C P
Sbjct: 2748 SNIAGEDELDFDVNIQVPPSFQKLWEIG-NMLDTGRNGEAKDVIINNP-ISLYCETNAAP 2805
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG 176
P +W KDG +T S ++ + R+L+I +ED G Y NE G
Sbjct: 2806 PPTLTWYKDGHPLTSSDKVLILPGG---RVLQIPRAKVEDAGRYTCVAVNEAG 2855
Score = 53.6 bits (123), Expect = 5e-07
Identities = 40/178 (22%), Positives = 66/178 (37%), Gaps = 15/178 (8%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
V EC+ G P P + W + ++ G L + D G YTC A N
Sbjct: 2029 VRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRI-LALTSAQISDTGRYTCVAVN 2087
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G+ + + L VY + P N V + V C P P +
Sbjct: 2088 AAGEKQRDIDLRVY-----------VPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLT 2136
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KDG + +++ E +L+I++ ++D G Y N G+ E + + +
Sbjct: 2137 WLKDGHPLLKKPGLSISENRS---VLKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNI 2191
Score = 52.8 bits (121), Expect = 9e-07
Identities = 46/179 (25%), Positives = 67/179 (37%), Gaps = 18/179 (10%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
V EC+ P P I W E ++ A G L+I D YTC ASN
Sbjct: 3639 VTLECKSDAVPPPVITWLRNGERLQ--ATPRVRILSGGRYLQINNADLGDTANYTCVASN 3696
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
GK L V + P P + V+ ++ +C +G P+P +
Sbjct: 3697 IAGKTTREFILTV-----------NVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRIT 3745
Query: 129 WDKDGSIITPS-ARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KDG+++ + AR ++ E L I + D G Y N G L+V
Sbjct: 3746 WRKDGAVLAGNHARYSILEN----GFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQV 3800
Score = 52.0 bits (119), Expect = 2e-06
Identities = 47/178 (26%), Positives = 68/178 (38%), Gaps = 12/178 (6%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
+ C+ P P + W+ + +D G L+I + ED G YTC A N
Sbjct: 2795 ISLYCETNAAPPPTLTWYKDGHPLTS-SDKVLILPGGRV-LQIPRAKVEDAGRYTCVAVN 2852
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G+ + Y R L P + A + P V ++ +C G+P+P S
Sbjct: 2853 EAGEDS-----LQYDVRVLVPPIIKGANS--DLPEEVTVLVNKSALIECLSSGSPAPRNS 2905
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KDG + RIL+I I D+G Y EN G A+ L V
Sbjct: 2906 WQKDGQPLLEDDHHKFLSNG---RILQILNTQITDIGRYVCVAENTAGSAKKYFNLNV 2960
Score = 50.8 bits (116), Expect = 4e-06
Identities = 45/179 (25%), Positives = 68/179 (37%), Gaps = 17/179 (9%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
V+ EC+ GNP P I W+ ++ ++ + + I+ D G Y C A N
Sbjct: 1938 VQLECKAAGNPVPVITWYKDNRLLSGSTSM--TFLNRGQIIDIESAQISDAGIYKCVAIN 1995
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G + L V+ +S +A V V +C +G P+P +
Sbjct: 1996 SAGATELFYSLQVHVAPSISGSNNMVA-----------VVVNNPVRLECEARGIPAPSLT 2044
Query: 129 WDKDGSIITP-SARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KDGS ++ S + V RIL + I D G Y N G + L V
Sbjct: 2045 WLKDGSPVSSFSNGLQVLSGG---RILALTSAQISDTGRYTCVAVNAAGEKQRDIDLRV 2100
Score = 48.8 bits (111), Expect = 1e-05
Identities = 40/171 (23%), Positives = 68/171 (39%), Gaps = 18/171 (10%)
Query: 8 TVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEAS 67
++ EC+ GNP P + W ++ A+ + G +L+I D G Y C A+
Sbjct: 1658 SLTLECKAAGNPSPILTWLKDGVPVK--ANDNIRIEAGGKKLEIMSAQEIDRGQYICVAT 1715
Query: 68 NCLGKAKSNACLVVYHTRRLSSPGRQMA--PTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
+ G+ + + Y L P + +++ N ++E C V G+P P
Sbjct: 1716 SVAGEKE-----IKYEVDVLVPPAIEGGDETSYFIVMVNNLLE------LDCHVTGSPPP 1764
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG 176
W KDG +I + R L I + + + G+YR N G
Sbjct: 1765 TIMWLKDGQLIDERDGFKILLNG---RKLVIAQAQVSNTGLYRCMAANTAG 1812
Score = 47.6 bits (108), Expect = 3e-05
Identities = 43/174 (24%), Positives = 57/174 (32%), Gaps = 16/174 (9%)
Query: 13 CQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLGK 72
C +G P P I W + D G + Q+ G YTC A N G
Sbjct: 3918 CTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQLN--HAGRYTCVARNAAGS 3975
Query: 73 AKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKD 132
A + L V+ P P V + C G PSP+ +W K+
Sbjct: 3976 AHRHVTLHVHEP-----------PVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKE 4024
Query: 133 GSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
G + S R L+I ED G Y +N G A +L V
Sbjct: 4025 GINVNTSGR---NHAVLPSGGLQISRAVREDAGTYMCVAQNPAGTALGKIKLNV 4075
Score = 47.2 bits (107), Expect = 4e-05
Identities = 48/180 (26%), Positives = 67/180 (37%), Gaps = 24/180 (13%)
Query: 12 ECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLG 71
EC G P P I W V+ S ++G ++ VT D G Y C A+N G
Sbjct: 3733 ECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLHIQSAHVT--DTGRYLCMATNAAG 3790
Query: 72 KAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDK 131
+ L V H +PG P N V T C G P P +W K
Sbjct: 3791 TDRRRIDLQV-HVPPSIAPG----------PTNMTVIVNVQTTLACEATGIPKPSINWRK 3839
Query: 132 DGSIITPSARITVKEKEEIMRILE-----IDEVSIEDVGIYRITVENELGRAEASARLEV 186
+G + + V + + R+L I S++D Y TV N G + + L V
Sbjct: 3840 NGHL------LNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGDDKRTVDLTV 3893
Score = 46.8 bits (106), Expect = 6e-05
Identities = 38/171 (22%), Positives = 63/171 (36%), Gaps = 14/171 (8%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G + C G P P + W + + D + L++ + ED G YTC
Sbjct: 3450 GSSTSMACITDGTPAPSMAWLRDGQPLG--LDAHLTVSTHGMVLQLLKAETEDSGKYTCI 3507
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
ASN G+ + L V ++ + +V +T C G P+P
Sbjct: 3508 ASNEAGEVSKHFILKVLEPPHINGSEEHEE-------ISVIVNNPLELT--CIASGIPAP 3558
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG 176
+W KDG + + ++ E++R I +ED G Y + G
Sbjct: 3559 KMTWMKDGRPLPQTDQVQTLGGGEVLR---ISTAQVEDTGRYTCLASSPAG 3606
Score = 42.3 bits (95), Expect = 0.001
Identities = 41/176 (23%), Positives = 60/176 (34%), Gaps = 18/176 (10%)
Query: 13 CQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLGK 72
C+ TG P P I W ++ + S + L I + +D TY C +N G
Sbjct: 3825 CEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGD 3884
Query: 73 AKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKD 132
K L V Q+ P+ P + +V + C G P P W K+
Sbjct: 3885 DKRTVDLTV-----------QVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKN 3933
Query: 133 GSIITPSARITVKEKEEIMR--ILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
G + P + I+ +EI + G Y N G A L V
Sbjct: 3934 GIRLLPRG-----DGYRILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHV 3984
Score = 41.9 bits (94), Expect = 0.002
Identities = 38/167 (22%), Positives = 59/167 (35%), Gaps = 8/167 (4%)
Query: 13 CQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLGK 72
C+ P I WF + + G L+I ++ G Y+C A+N G+
Sbjct: 2597 CEAYSYPPATITWFKDGTPLESNRNIRIL--PGGRTLQILNAQEDNAGRYSCVATNEAGE 2654
Query: 73 AKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKD 132
+ + VY + + G P P ++ +T +C PS SW KD
Sbjct: 2655 MIKHYEVKVY-IPPIINKGDLWGPGLS--PKEVKIKVNNTLTLECEAYAIPSASLSWYKD 2711
Query: 133 GSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAE 179
G + + + L+I E I D G Y N G E
Sbjct: 2712 GQPLKSDDHVNIAANG---HTLQIKEAQISDTGRYTCVASNIAGEDE 2755
Score = 40.7 bits (91), Expect = 0.004
Identities = 36/169 (21%), Positives = 61/169 (36%), Gaps = 14/169 (8%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
+E C +G P P + W + ++ G L+I ED G YTC AS+
Sbjct: 3546 LELTCIASGIPAPKMTWMKDGRPLPQTDQVQTL--GGGEVLRISTAQVEDTGRYTCLASS 3603
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G + V+ ++ P + V VT +C P P +
Sbjct: 3604 PAGDDDKEYLVRVHVPPNIAGTDE---------PRDITVLRNRQVTLECKSDAVPPPVIT 3654
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGR 177
W ++G + + R+ + R L+I+ + D Y N G+
Sbjct: 3655 WLRNGERLQATPRVRILSGG---RYLQINNADLGDTANYTCVASNIAGK 3700
Score = 40.3 bits (90), Expect = 0.005
Identities = 34/139 (24%), Positives = 52/139 (37%), Gaps = 15/139 (10%)
Query: 49 LKIKQVTAEDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVE 108
L++K V D G Y C S+ G + ++ L V Q P P N+
Sbjct: 576 LELKSVKFNDAGEYHCMVSSEGGSSAASVFLTV-----------QEPPKVTVMPKNQSFT 624
Query: 109 EGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYR 168
G V+ C+ G P P +W + I S R + + I + +D GIY
Sbjct: 625 GGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGTLF----IKNAAPKDAGIYG 680
Query: 169 ITVENELGRAEASARLEVI 187
N G + ++ L I
Sbjct: 681 CLASNSAGTDKQNSTLRYI 699
Score = 39.9 bits (89), Expect = 0.007
Identities = 43/175 (24%), Positives = 63/175 (36%), Gaps = 15/175 (8%)
Query: 12 ECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLG 71
EC +G+P P W + + + D +G L+I D G Y C A N G
Sbjct: 2893 ECLSSGSPAPRNSWQKDGQPLLE-DDHHKFLSNGRI-LQILNTQITDIGRYVCVAENTAG 2950
Query: 72 KAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDK 131
AK L V+ + P + N V ++ C V G P P SW K
Sbjct: 2951 SAKKYFNLNVHVPPSVIGPKSE----------NLTVVVNNFISLTCEVSGFPPPDLSWLK 3000
Query: 132 DGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
+ I + + R L+I + D G Y N+ G ++ L V
Sbjct: 3001 NEQPIKLNTNTLIVPGG---RTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTV 3052
Score = 39.1 bits (87), Expect = 0.012
Identities = 35/144 (24%), Positives = 53/144 (36%), Gaps = 13/144 (9%)
Query: 43 DDGTARLKIKQVTAEDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYP 102
+ + L I +VT DEG Y C A + G ++ V S P P P
Sbjct: 478 ESASVNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDV------SEP-----PPVIQVP 526
Query: 103 FNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIE 162
N V GE C + +W ++ + + ++ + LE+ V
Sbjct: 527 NNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLS--LELKSVKFN 584
Query: 163 DVGIYRITVENELGRAEASARLEV 186
D G Y V +E G + AS L V
Sbjct: 585 DAGEYHCMVSSEGGSSAASVFLTV 608
>AL135796-1|CAI17854.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-164L12 on chromosome 1. ).
Length = 5635
Score = 75.4 bits (177), Expect = 1e-13
Identities = 55/183 (30%), Positives = 78/183 (42%), Gaps = 10/183 (5%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G V C+ +GNP P + W E+I + S+ DG+ L + E+ G Y C
Sbjct: 994 EGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGS--LYVVSPGGEESGEYVC 1051
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
A+N G AK L VY R+ R ++ P V GE VT C VK P
Sbjct: 1052 TATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQD---KPVEISVLAGEEVTLPCEVKSLPP 1108
Query: 125 PWASWDKDGSIITP-SARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
P +W K+ +I+P S R T ++I E D G+Y N G + +
Sbjct: 1109 PIITWAKETQLISPFSPRHTFLPSGS----MKITETRTSDSGMYLCVATNIAGNVTQAVK 1164
Query: 184 LEV 186
L V
Sbjct: 1165 LNV 1167
Score = 74.5 bits (175), Expect = 3e-13
Identities = 48/178 (26%), Positives = 75/178 (42%), Gaps = 13/178 (7%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
V +C G P+P I W + + G L+I + ED G YTC A+N
Sbjct: 1844 VALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATN 1902
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G+ + + L V+ L G+ + N+ V V +C GNP P +
Sbjct: 1903 AAGETQQHIQLHVHEPPSLEDAGKML---------NETVLVSNPVQLECKAAGNPVPVIT 1953
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KD +++ S +T + + I++I+ I D GIY+ N G E L+V
Sbjct: 1954 WYKDNRLLSGSTSMTFLNRGQ---IIDIESAQISDAGIYKCVAINSAGATELFYSLQV 2008
Score = 70.9 bits (166), Expect = 3e-12
Identities = 60/180 (33%), Positives = 80/180 (44%), Gaps = 20/180 (11%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+ + C+ TG P P + W +I A F+S +G + L I++V+ ED GTY C
Sbjct: 4274 GEQLRLSCKATGIPLPKLTWTFNNNIIP--AHFDSV--NGHSELVIERVSKEDSGTYVCT 4329
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFY-TYPFNKVVEEGENVTFKCAVKGNPS 124
A N +G K A VY + P P F YP N + G N C VKG+P+
Sbjct: 4330 AENSVGFVK--AIGFVY----VKEP-----PVFKGDYPSNWIEPLGGNAILNCEVKGDPT 4378
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
P W++ G I S RI ++ L I ED G Y NE G E S L
Sbjct: 4379 PTIQWNRKGVDIEISHRI----RQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSL 4434
Score = 68.5 bits (160), Expect = 2e-11
Identities = 47/179 (26%), Positives = 78/179 (43%), Gaps = 13/179 (7%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
++ EC+ G P P I W+ + I + ++ Y D L I + D TYTC +N
Sbjct: 1565 IKLECETRGLPMPAITWYKDGQPIMSSS--QALYIDKGQYLHIPRAQVSDSATYTCHVAN 1622
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G A+ + + VY + +A P NK V ++T +C GNPSP +
Sbjct: 1623 VAGTAEKSFHVDVYVPPMIEG---NLAT-----PLNKQVVIAHSLTLECKAAGNPSPILT 1674
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVI 187
W KDG + + I ++ + + I+ E+ D G Y + G E ++V+
Sbjct: 1675 WLKDGVPVKANDNIRIEAGGKKLEIMSAQEI---DRGQYICVATSVAGEKEIKYEVDVL 1730
Score = 67.7 bits (158), Expect = 3e-11
Identities = 43/182 (23%), Positives = 79/182 (43%), Gaps = 11/182 (6%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G+ + C+ +G P P++ W + + G +L+I D Y+C
Sbjct: 2210 EGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSC 2269
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
ASN G AK L VY +++ G ++P +V G++++ +C V+G P
Sbjct: 2270 VASNVAGTAKKEYNLQVYIRPTITNSG--------SHPTEIIVTRGKSISLECEVQGIPP 2321
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
P +W KDG + + + + ++ IL++ + + D G Y N G + L
Sbjct: 2322 PTVTWMKDGHPLIKAKGVEILDEG---HILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDL 2378
Query: 185 EV 186
V
Sbjct: 2379 SV 2380
Score = 66.5 bits (155), Expect = 7e-11
Identities = 53/174 (30%), Positives = 73/174 (41%), Gaps = 16/174 (9%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFE-SSYDD-GTARLKIKQVTAEDEGTYT 63
G V C V G P+P I+W + F SS T L I + A D+GTY
Sbjct: 807 GSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYI 866
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCA-VKGN 122
CEA N GK +S + V +AP P V EG+ +T C + GN
Sbjct: 867 CEAENQFGKIQSETTVTVTGL---------VAPLIGISPSVANVIEGQQLTLPCTLLAGN 917
Query: 123 PSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG 176
P P W K+ +++ + ITV+ L I+ V ++D G Y N G
Sbjct: 918 PIPERRWIKNSAMLLQNPYITVRSDGS----LHIERVQLQDGGEYTCVASNVAG 967
Score = 66.5 bits (155), Expect = 7e-11
Identities = 50/178 (28%), Positives = 71/178 (39%), Gaps = 13/178 (7%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
V ECQV G P PDI WF + + D D L +K D+G Y C SN
Sbjct: 1471 VALECQVKGTPFPDIHWFKDGKPL-FLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSN 1529
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
GK + L +Y + T + N +++ +C +G P P +
Sbjct: 1530 AAGKQAKDIKLTIYIPPSIKGGN---VTTDISVLINSLIK------LECETRGLPMPAIT 1580
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KDG I S++ +K + L I + D Y V N G AE S ++V
Sbjct: 1581 WYKDGQPIMSSSQALYIDKGQ---YLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDV 1635
Score = 65.7 bits (153), Expect = 1e-10
Identities = 46/178 (25%), Positives = 74/178 (41%), Gaps = 12/178 (6%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
+ C+V+G P PD+ W + I+ + + G L+I + D G YTC A N
Sbjct: 2982 ISLTCEVSGFPPPDLSWLKNEQPIK--LNTNTLIVPGGRTLQIIRAKVSDGGEYTCIAIN 3039
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G++K L VY + + V EG +V+ +C P P +
Sbjct: 3040 QAGESKKKFSLTVYVPPSIKDHDSESLSVVN-------VREGTSVSLECESNAVPPPVIT 3092
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W K+G +IT S + + + +L I + + D G Y N GR + + L V
Sbjct: 3093 WYKNGRMITESTHVEILADGQ---MLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNV 3147
Score = 65.3 bits (152), Expect = 2e-10
Identities = 52/182 (28%), Positives = 75/182 (41%), Gaps = 14/182 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
GD EC+ +G P P ++WF +R D LKI++ D G YTC
Sbjct: 716 GDITVMECKTSGIPPPQVKWFKGDLELRPSTFL--IIDPLLGLLKIQETQDLDAGDYTCV 773
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A N G+A L V SP P F P + +E G NVT C V+G P P
Sbjct: 774 AINEAGRATGKITLDV------GSP-----PVFIQEPADVSMEIGSNVTLPCYVQGYPEP 822
Query: 126 WASWDKDGSIITPSARITVKEKEEIMR-ILEIDEVSIEDVGIYRITVENELGRAEASARL 184
W + ++ S +V ++ L I + D G Y EN+ G+ ++ +
Sbjct: 823 TIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTV 882
Query: 185 EV 186
V
Sbjct: 883 TV 884
Score = 64.9 bits (151), Expect = 2e-10
Identities = 57/198 (28%), Positives = 82/198 (41%), Gaps = 19/198 (9%)
Query: 5 DGDTVEFECQV-TGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYT 63
+G + C + GNP P+ RW + ++ + + DG+ L I++V +D G YT
Sbjct: 903 EGQQLTLPCTLLAGNPIPERRWIKNSAMLLQ-NPYITVRSDGS--LHIERVQLQDGGEYT 959
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
C ASN G +VV H G+Q+ T EG VT C GNP
Sbjct: 960 CVASNVAGTNNKTTSVVV-HVLPTIQHGQQILSTI----------EGIPVTLPCKASGNP 1008
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
P W K G +I+ S + K L + E+ G Y T N G A+ +
Sbjct: 1009 KPSVIWSKKGELISTS---SAKFSAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKVQ 1065
Query: 184 LEVITRSGKFYGGLRAYS 201
L V R + +G R S
Sbjct: 1066 LTVYVRP-RVFGDQRGLS 1082
Score = 63.7 bits (148), Expect = 5e-10
Identities = 53/181 (29%), Positives = 70/181 (38%), Gaps = 17/181 (9%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G V C TG P P I W I + + DGT L IK +D G Y C
Sbjct: 626 GSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMT-SDGT--LFIKNAAPKDAGIYGCL 682
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
ASN G K N+ L R + AP +V G+ +C G P P
Sbjct: 683 ASNSAGTDKQNSTL-----RYIE------APKLMVVQSELLVALGDITVMECKTSGIPPP 731
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
W K + PS + + + ++ +L+I E D G Y NE GRA L+
Sbjct: 732 QVKWFKGDLELRPSTFLII---DPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLD 788
Query: 186 V 186
V
Sbjct: 789 V 789
Score = 63.7 bits (148), Expect = 5e-10
Identities = 47/178 (26%), Positives = 78/178 (43%), Gaps = 14/178 (7%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
+E +C VTG+P P I W ++I + F+ + +L I Q + G Y C A+N
Sbjct: 1752 LELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNG--RKLVIAQAQVSNTGLYRCMAAN 1809
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G K + V+ + S G +VV + + V +C G P+P +
Sbjct: 1810 TAGDHKKEFEVTVHVPPTIKSSGLS----------ERVVVKYKPVALQCIANGIPNPSIT 1859
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KD + +A+ +K + R+L+I + +ED G Y N G + +L V
Sbjct: 1860 WLKDDQPVN-TAQGNLKIQSS-GRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHV 1915
Score = 63.3 bits (147), Expect = 6e-10
Identities = 47/182 (25%), Positives = 73/182 (40%), Gaps = 13/182 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G ++ EC+V G P P + W + E D+G L++K + D G Y C
Sbjct: 2307 GKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEI-LDEGHI-LQLKNIHVSDTGRYVCV 2364
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A N G L V+ + R P N V E +V+ C G P P
Sbjct: 2365 AVNVAGMTDKKYDLSVHAPPSIIGNHRS--------PENISVVEKNSVSLTCEASGIPLP 2416
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
+W KDG ++ S + + ++R++ + ++ED G Y V N G L
Sbjct: 2417 SITWFKDGWPVSLSNSVRILSGGRMLRLM---QTTMEDAGQYTCVVRNAAGEERKIFGLS 2473
Query: 186 VI 187
V+
Sbjct: 2474 VL 2475
Score = 62.9 bits (146), Expect = 8e-10
Identities = 50/179 (27%), Positives = 71/179 (39%), Gaps = 13/179 (7%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
+EF C G P P I+W H + S +DGT L I VT D G Y C A N
Sbjct: 1284 IEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGTL-LVIASVTPYDNGEYICVAVN 1342
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G + L V H + Q+ N V + C V+G PSP
Sbjct: 1343 EAGTTERKYNLKV-HVPPVIKDKEQVT--------NVSVLLNQLTNLFCEVEGTPSPIIM 1393
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVI 187
W KD +T S+ I +I+++ + ED G Y N G ++ ++V+
Sbjct: 1394 WYKDNVQVTESSTIQTVNNGKILKLF---RATPEDAGRYSCKAINIAGTSQKYFNIDVL 1449
Score = 62.1 bits (144), Expect = 1e-09
Identities = 52/182 (28%), Positives = 71/182 (39%), Gaps = 12/182 (6%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G V+ C G P P I W + + S DGT L I Q T D G YTC
Sbjct: 1185 GQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGT--LSIDQATPSDAGIYTCV 1242
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A+N G ++ L V + + P + T +V + + F C KG P P
Sbjct: 1243 ATNIAGTDETEITLHVQEPPTVED----LEPPYNTTFQERVANQ--RIEFPCPAKGTPKP 1296
Query: 126 WASWDKDGSIIT-PSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
W +G +T I++ E +L I V+ D G Y NE G E L
Sbjct: 1297 TIKWLHNGRELTGREPGISILEDG---TLLVIASVTPYDNGEYICVAVNEAGTTERKYNL 1353
Query: 185 EV 186
+V
Sbjct: 1354 KV 1355
Score = 61.7 bits (143), Expect = 2e-09
Identities = 47/181 (25%), Positives = 68/181 (37%), Gaps = 16/181 (8%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+ V C+V P P I W ++I + + G+ +KI + D G Y C
Sbjct: 1094 GEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGS--MKITETRTSDSGMYLCV 1151
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A+N G L V+ + P P + V+ G+ V C +G P P
Sbjct: 1152 ATNIAGNVTQAVKLNVH-----------VPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLP 1200
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
+W K GS + V + L ID+ + D GIY N G E L
Sbjct: 1201 VITWSKGGSTMLVDGEHHVSNPD---GTLSIDQATPSDAGIYTCVATNIAGTDETEITLH 1257
Query: 186 V 186
V
Sbjct: 1258 V 1258
Score = 61.3 bits (142), Expect = 3e-09
Identities = 50/178 (28%), Positives = 64/178 (35%), Gaps = 10/178 (5%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
V C TG P P I W + I + E G ++L+I + D G YTC ASN
Sbjct: 3169 VTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASN 3228
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
GKA+ Y+ + P P + V GENV C G P+P
Sbjct: 3229 MEGKAQK------YYFLSIQVPPSVAGAEI---PSDVSVLLGENVELVCNANGIPTPLIQ 3279
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KDG I ++ L I D G Y N G + L V
Sbjct: 3280 WLKDGKPIASGETERIRVSAN-GSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNV 3336
Score = 60.1 bits (139), Expect = 6e-09
Identities = 48/168 (28%), Positives = 73/168 (43%), Gaps = 18/168 (10%)
Query: 13 CQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLGK 72
C G P P I W ++ + ++ G L ++ V ED G YTC A+N G+
Sbjct: 4190 CVADGIPTPAINWKKDNVLLANLLGKYTAEPYG--ELILENVVLEDSGFYTCVANNAAGE 4247
Query: 73 AKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKD 132
L V+ + PTF P + + +GE + C G P P +W +
Sbjct: 4248 DTHTVSLTVH-----------VLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFN 4296
Query: 133 GSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEA 180
+II P+ +V E++ I+ VS ED G Y T EN +G +A
Sbjct: 4297 NNII-PAHFDSVNGHSELV----IERVSKEDSGTYVCTAENSVGFVKA 4339
Score = 58.0 bits (134), Expect = 2e-08
Identities = 44/175 (25%), Positives = 75/175 (42%), Gaps = 15/175 (8%)
Query: 13 CQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLGK 72
C+V G P P I W+ + + + ++ ++G LK+ + T ED G Y+C+A N G
Sbjct: 1382 CEVEGTPSPIIMWYKDNVQVTESSTIQT-VNNGKI-LKLFRATPEDAGRYSCKAINIAGT 1439
Query: 73 AKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKD 132
++ Y + P + F P V +V +C VKG P P W KD
Sbjct: 1440 SQK------YFNIDVLVPPTIIGTNF---PNEVSVVLNRDVALECQVKGTPFPDIHWFKD 1490
Query: 133 GS-IITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
G + + + ++ + +L + D G Y+ TV N G+ +L +
Sbjct: 1491 GKPLFLGDPNVELLDRGQ---VLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTI 1542
Score = 57.6 bits (133), Expect = 3e-08
Identities = 49/176 (27%), Positives = 69/176 (39%), Gaps = 15/176 (8%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G +V EC+ P P I W+ +I + E D L IK+ D G Y C
Sbjct: 3073 EGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADG--QMLHIKKAEVSDTGQYVC 3130
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGEN-VTFKCAVKGNP 123
A N G+ N L VY + P R++ +VE N VT C G P
Sbjct: 3131 RAINVAGRDDKNFHLNVYVPPSIEGPEREV-----------IVETISNPVTLTCDATGIP 3179
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAE 179
P +W K+ I S + V+ + L+I D G Y N G+A+
Sbjct: 3180 PPTIAWLKNHKRIENSDSLEVRILSGGSK-LQIARSQHSDSGNYTCIASNMEGKAQ 3234
Score = 57.2 bits (132), Expect = 4e-08
Identities = 54/200 (27%), Positives = 74/200 (37%), Gaps = 29/200 (14%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSY---DDGTARLKIKQVTAEDEGTY 62
G C+V G+P P I+W R D E S+ G L I ED G Y
Sbjct: 4364 GGNAILNCEVKGDPTPTIQWN------RKGVDIEISHRIRQLGNGSLAIYGTVNEDAGDY 4417
Query: 63 TCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGN 122
TC A+N G + + L L SP P P V+ G + C G
Sbjct: 4418 TCVATNEAGVVERSMSLT------LQSP-----PIITLEPVETVINAGGKIILNCQATGE 4466
Query: 123 PSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASA 182
P P +W + G I+ R+ V L I + ED + N +G
Sbjct: 4467 PQPTITWSRQGHSISWDDRVNVLSNNS----LYIADAQKEDTSEFECVARNLMG--SVLV 4520
Query: 183 RLEVITRSGKFYGGLRAYSA 202
R+ VI + +GG +SA
Sbjct: 4521 RVPVIV---QVHGGFSQWSA 4537
Score = 56.8 bits (131), Expect = 6e-08
Identities = 48/178 (26%), Positives = 69/178 (38%), Gaps = 17/178 (9%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
+ C+ G P PDI W I + + G+ L+I V D G YTC A+N
Sbjct: 4096 ITLSCEADGLPPPDITWHKDGRAIVESIR-QRVLSSGS--LQIAFVQPGDAGHYTCMAAN 4152
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G + ++ L V+ R+ S YT V E C G P+P +
Sbjct: 4153 VAGSSSTSTKLTVHVPPRIRS-----TEGHYT------VNENSQAILPCVADGIPTPAIN 4201
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KD ++ A + K E L ++ V +ED G Y N G + L V
Sbjct: 4202 WKKDNVLL---ANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHTVSLTV 4256
Score = 56.4 bits (130), Expect = 7e-08
Identities = 46/181 (25%), Positives = 70/181 (38%), Gaps = 11/181 (6%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+ VE C G P P I+W + I + L I D G YTC
Sbjct: 3261 GENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCV 3320
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A+N G+ L VY T + + A T +V+ N+ +C G P P
Sbjct: 3321 ATNPAGEEDRIFNLNVYVTPTIRG-NKDEAEKLMT-----LVDTSINI--ECRATGTPPP 3372
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
+W K+G + S+ I + +++RI+ + DV +Y N G L+
Sbjct: 3373 QINWLKNGLPLPLSSHIRLLAAGQVIRIV---RAQVSDVAVYTCVASNRAGVDNKHYNLQ 3429
Query: 186 V 186
V
Sbjct: 3430 V 3430
Score = 56.4 bits (130), Expect = 7e-08
Identities = 49/174 (28%), Positives = 63/174 (36%), Gaps = 17/174 (9%)
Query: 13 CQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLGK 72
C+ TG P P I W + + G L+I + ED GTY C A N G
Sbjct: 4009 CEATGTPSPFITWQKEGINVNTSGRNHAVLPSGG--LQISRAVREDAGTYMCVAQNPAGT 4066
Query: 73 AKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKD 132
A L V Q+ P + V+ + +T C G P P +W KD
Sbjct: 4067 ALGKIKLNV-----------QVPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKD 4115
Query: 133 GSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
G I S R V L+I V D G Y N G + S +L V
Sbjct: 4116 GRAIVESIRQRVLSSGS----LQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTV 4165
Score = 56.0 bits (129), Expect = 1e-07
Identities = 45/180 (25%), Positives = 72/180 (40%), Gaps = 14/180 (7%)
Query: 8 TVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEAS 67
++ EC+ TG P P I W + + R+ QV+ D YTC AS
Sbjct: 3359 SINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVS--DVAVYTCVAS 3416
Query: 68 NCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWA 127
N G + L V+ + + M T V +G + + C G P+P
Sbjct: 3417 NRAGVDNKHYNLQVFAPPNMDN---SMGTEEIT------VLKGSSTSMACITDGTPAPSM 3467
Query: 128 SWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVI 187
+W +DG + A +TV ++++L+ + ED G Y NE G L+V+
Sbjct: 3468 AWLRDGQPLGLDAHLTVSTHGMVLQLLKAE---TEDSGKYTCIASNEAGEVSKHFILKVL 3524
Score = 55.6 bits (128), Expect = 1e-07
Identities = 48/183 (26%), Positives = 70/183 (38%), Gaps = 16/183 (8%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
VE CQ P P + W + S + + LKI+ +D G YTCEA+N
Sbjct: 2121 VELLCQSDAIPPPTLTWLKDGHPLLKKPGL--SISENRSVLKIEDAQVQDTGRYTCEATN 2178
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
GK + N + ++ + T V EG ++ C G P P
Sbjct: 2179 VAGKTEKNYNVNIWVPPNIGGSDELTQLT---------VIEGNLISLLCESSGIPPPNLI 2229
Query: 129 WDKDGS-IITPS-ARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W K GS ++T S R+ + R L+I D +Y N G A+ L+V
Sbjct: 2230 WKKKGSPVLTDSMGRVRILSGG---RQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQV 2286
Query: 187 ITR 189
R
Sbjct: 2287 YIR 2289
Score = 55.2 bits (127), Expect = 2e-07
Identities = 48/180 (26%), Positives = 66/180 (36%), Gaps = 14/180 (7%)
Query: 7 DTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEA 66
++V C+ +G P P I WF + G L++ Q T ED G YTC
Sbjct: 2402 NSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRIL--SGGRMLRLMQTTMEDAGQYTCVV 2459
Query: 67 SNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPW 126
N G+ + ++ L P T V+E ++VT C V GNP P
Sbjct: 2460 RNAAGEERK-----IFGLSVLVPPHIVGENTLEDVK----VKEKQSVTLTCEVTGNPVPE 2510
Query: 127 ASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
+W KDG P R L+I V + G Y + G S L V
Sbjct: 2511 ITWHKDGQ---PLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNV 2567
Score = 54.4 bits (125), Expect = 3e-07
Identities = 43/169 (25%), Positives = 67/169 (39%), Gaps = 11/169 (6%)
Query: 8 TVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEAS 67
+V C+VTGNP P+I W + +++ D G L+I V G YTC AS
Sbjct: 2496 SVTLTCEVTGNPVPEITWHKDGQPLQE--DEAHHIISGGRFLQITNVQVPHTGRYTCLAS 2553
Query: 68 NCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWA 127
+ G + L V+ + ++ G P T N + C P
Sbjct: 2554 SPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILN------SPTSLVCEAYSYPPATI 2607
Query: 128 SWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG 176
+W KDG+ + + I + ++IL E ++ G Y NE G
Sbjct: 2608 TWFKDGTPLESNRNIRILPGGRTLQILNAQE---DNAGRYSCVATNEAG 2653
Score = 54.4 bits (125), Expect = 3e-07
Identities = 43/173 (24%), Positives = 72/173 (41%), Gaps = 10/173 (5%)
Query: 7 DTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEA 66
+T+ EC+ P + W+ + ++ + + T L+IK+ D G YTC A
Sbjct: 2690 NTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHT--LQIKEAQISDTGRYTCVA 2747
Query: 67 SNCLGKAKSNACL---VVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
SN G+ + + + V ++L G M T V+ ++ C P
Sbjct: 2748 SNIAGEDELDFDVNIQVPPSFQKLWEIG-NMLDTGRNGEAKDVIINNP-ISLYCETNAAP 2805
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG 176
P +W KDG +T S ++ + R+L+I +ED G Y NE G
Sbjct: 2806 PPTLTWYKDGHPLTSSDKVLILPGG---RVLQIPRAKVEDAGRYTCVAVNEAG 2855
Score = 53.6 bits (123), Expect = 5e-07
Identities = 40/178 (22%), Positives = 66/178 (37%), Gaps = 15/178 (8%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
V EC+ G P P + W + ++ G L + D G YTC A N
Sbjct: 2029 VRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRI-LALTSAQISDTGRYTCVAVN 2087
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G+ + + L VY + P N V + V C P P +
Sbjct: 2088 AAGEKQRDIDLRVY-----------VPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLT 2136
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KDG + +++ E +L+I++ ++D G Y N G+ E + + +
Sbjct: 2137 WLKDGHPLLKKPGLSISENRS---VLKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNI 2191
Score = 52.8 bits (121), Expect = 9e-07
Identities = 46/179 (25%), Positives = 67/179 (37%), Gaps = 18/179 (10%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
V EC+ P P I W E ++ A G L+I D YTC ASN
Sbjct: 3639 VTLECKSDAVPPPVITWLRNGERLQ--ATPRVRILSGGRYLQINNADLGDTANYTCVASN 3696
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
GK L V + P P + V+ ++ +C +G P+P +
Sbjct: 3697 IAGKTTREFILTV-----------NVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRIT 3745
Query: 129 WDKDGSIITPS-ARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KDG+++ + AR ++ E L I + D G Y N G L+V
Sbjct: 3746 WRKDGAVLAGNHARYSILEN----GFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQV 3800
Score = 52.0 bits (119), Expect = 2e-06
Identities = 47/178 (26%), Positives = 68/178 (38%), Gaps = 12/178 (6%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
+ C+ P P + W+ + +D G L+I + ED G YTC A N
Sbjct: 2795 ISLYCETNAAPPPTLTWYKDGHPLTS-SDKVLILPGGRV-LQIPRAKVEDAGRYTCVAVN 2852
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G+ + Y R L P + A + P V ++ +C G+P+P S
Sbjct: 2853 EAGEDS-----LQYDVRVLVPPIIKGANS--DLPEEVTVLVNKSALIECLSSGSPAPRNS 2905
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KDG + RIL+I I D+G Y EN G A+ L V
Sbjct: 2906 WQKDGQPLLEDDHHKFLSNG---RILQILNTQITDIGRYVCVAENTAGSAKKYFNLNV 2960
Score = 50.8 bits (116), Expect = 4e-06
Identities = 45/179 (25%), Positives = 68/179 (37%), Gaps = 17/179 (9%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
V+ EC+ GNP P I W+ ++ ++ + + I+ D G Y C A N
Sbjct: 1938 VQLECKAAGNPVPVITWYKDNRLLSGSTSM--TFLNRGQIIDIESAQISDAGIYKCVAIN 1995
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G + L V+ +S +A V V +C +G P+P +
Sbjct: 1996 SAGATELFYSLQVHVAPSISGSNNMVA-----------VVVNNPVRLECEARGIPAPSLT 2044
Query: 129 WDKDGSIITP-SARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KDGS ++ S + V RIL + I D G Y N G + L V
Sbjct: 2045 WLKDGSPVSSFSNGLQVLSGG---RILALTSAQISDTGRYTCVAVNAAGEKQRDIDLRV 2100
Score = 48.8 bits (111), Expect = 1e-05
Identities = 40/171 (23%), Positives = 68/171 (39%), Gaps = 18/171 (10%)
Query: 8 TVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEAS 67
++ EC+ GNP P + W ++ A+ + G +L+I D G Y C A+
Sbjct: 1658 SLTLECKAAGNPSPILTWLKDGVPVK--ANDNIRIEAGGKKLEIMSAQEIDRGQYICVAT 1715
Query: 68 NCLGKAKSNACLVVYHTRRLSSPGRQMA--PTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
+ G+ + + Y L P + +++ N ++E C V G+P P
Sbjct: 1716 SVAGEKE-----IKYEVDVLVPPAIEGGDETSYFIVMVNNLLE------LDCHVTGSPPP 1764
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG 176
W KDG +I + R L I + + + G+YR N G
Sbjct: 1765 TIMWLKDGQLIDERDGFKILLNG---RKLVIAQAQVSNTGLYRCMAANTAG 1812
Score = 47.6 bits (108), Expect = 3e-05
Identities = 43/174 (24%), Positives = 57/174 (32%), Gaps = 16/174 (9%)
Query: 13 CQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLGK 72
C +G P P I W + D G + Q+ G YTC A N G
Sbjct: 3918 CTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQLN--HAGRYTCVARNAAGS 3975
Query: 73 AKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKD 132
A + L V+ P P V + C G PSP+ +W K+
Sbjct: 3976 AHRHVTLHVHEP-----------PVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKE 4024
Query: 133 GSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
G + S R L+I ED G Y +N G A +L V
Sbjct: 4025 GINVNTSGR---NHAVLPSGGLQISRAVREDAGTYMCVAQNPAGTALGKIKLNV 4075
Score = 47.2 bits (107), Expect = 4e-05
Identities = 48/180 (26%), Positives = 67/180 (37%), Gaps = 24/180 (13%)
Query: 12 ECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLG 71
EC G P P I W V+ S ++G ++ VT D G Y C A+N G
Sbjct: 3733 ECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLHIQSAHVT--DTGRYLCMATNAAG 3790
Query: 72 KAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDK 131
+ L V H +PG P N V T C G P P +W K
Sbjct: 3791 TDRRRIDLQV-HVPPSIAPG----------PTNMTVIVNVQTTLACEATGIPKPSINWRK 3839
Query: 132 DGSIITPSARITVKEKEEIMRILE-----IDEVSIEDVGIYRITVENELGRAEASARLEV 186
+G + + V + + R+L I S++D Y TV N G + + L V
Sbjct: 3840 NGHL------LNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGDDKRTVDLTV 3893
Score = 46.8 bits (106), Expect = 6e-05
Identities = 38/171 (22%), Positives = 63/171 (36%), Gaps = 14/171 (8%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G + C G P P + W + + D + L++ + ED G YTC
Sbjct: 3450 GSSTSMACITDGTPAPSMAWLRDGQPLG--LDAHLTVSTHGMVLQLLKAETEDSGKYTCI 3507
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
ASN G+ + L V ++ + +V +T C G P+P
Sbjct: 3508 ASNEAGEVSKHFILKVLEPPHINGSEEHEE-------ISVIVNNPLELT--CIASGIPAP 3558
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG 176
+W KDG + + ++ E++R I +ED G Y + G
Sbjct: 3559 KMTWMKDGRPLPQTDQVQTLGGGEVLR---ISTAQVEDTGRYTCLASSPAG 3606
Score = 42.3 bits (95), Expect = 0.001
Identities = 41/176 (23%), Positives = 60/176 (34%), Gaps = 18/176 (10%)
Query: 13 CQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLGK 72
C+ TG P P I W ++ + S + L I + +D TY C +N G
Sbjct: 3825 CEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGD 3884
Query: 73 AKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKD 132
K L V Q+ P+ P + +V + C G P P W K+
Sbjct: 3885 DKRTVDLTV-----------QVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKN 3933
Query: 133 GSIITPSARITVKEKEEIMR--ILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
G + P + I+ +EI + G Y N G A L V
Sbjct: 3934 GIRLLPRG-----DGYRILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHV 3984
Score = 41.9 bits (94), Expect = 0.002
Identities = 38/167 (22%), Positives = 59/167 (35%), Gaps = 8/167 (4%)
Query: 13 CQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLGK 72
C+ P I WF + + G L+I ++ G Y+C A+N G+
Sbjct: 2597 CEAYSYPPATITWFKDGTPLESNRNIRIL--PGGRTLQILNAQEDNAGRYSCVATNEAGE 2654
Query: 73 AKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKD 132
+ + VY + + G P P ++ +T +C PS SW KD
Sbjct: 2655 MIKHYEVKVY-IPPIINKGDLWGPGLS--PKEVKIKVNNTLTLECEAYAIPSASLSWYKD 2711
Query: 133 GSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAE 179
G + + + L+I E I D G Y N G E
Sbjct: 2712 GQPLKSDDHVNIAANG---HTLQIKEAQISDTGRYTCVASNIAGEDE 2755
Score = 40.7 bits (91), Expect = 0.004
Identities = 36/169 (21%), Positives = 61/169 (36%), Gaps = 14/169 (8%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
+E C +G P P + W + ++ G L+I ED G YTC AS+
Sbjct: 3546 LELTCIASGIPAPKMTWMKDGRPLPQTDQVQTL--GGGEVLRISTAQVEDTGRYTCLASS 3603
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G + V+ ++ P + V VT +C P P +
Sbjct: 3604 PAGDDDKEYLVRVHVPPNIAGTDE---------PRDITVLRNRQVTLECKSDAVPPPVIT 3654
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGR 177
W ++G + + R+ + R L+I+ + D Y N G+
Sbjct: 3655 WLRNGERLQATPRVRILSGG---RYLQINNADLGDTANYTCVASNIAGK 3700
Score = 40.3 bits (90), Expect = 0.005
Identities = 34/139 (24%), Positives = 52/139 (37%), Gaps = 15/139 (10%)
Query: 49 LKIKQVTAEDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVE 108
L++K V D G Y C S+ G + ++ L V Q P P N+
Sbjct: 576 LELKSVKFNDAGEYHCMVSSEGGSSAASVFLTV-----------QEPPKVTVMPKNQSFT 624
Query: 109 EGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYR 168
G V+ C+ G P P +W + I S R + + I + +D GIY
Sbjct: 625 GGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGTLF----IKNAAPKDAGIYG 680
Query: 169 ITVENELGRAEASARLEVI 187
N G + ++ L I
Sbjct: 681 CLASNSAGTDKQNSTLRYI 699
Score = 39.9 bits (89), Expect = 0.007
Identities = 43/175 (24%), Positives = 63/175 (36%), Gaps = 15/175 (8%)
Query: 12 ECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLG 71
EC +G+P P W + + + D +G L+I D G Y C A N G
Sbjct: 2893 ECLSSGSPAPRNSWQKDGQPLLE-DDHHKFLSNGRI-LQILNTQITDIGRYVCVAENTAG 2950
Query: 72 KAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDK 131
AK L V+ + P + N V ++ C V G P P SW K
Sbjct: 2951 SAKKYFNLNVHVPPSVIGPKSE----------NLTVVVNNFISLTCEVSGFPPPDLSWLK 3000
Query: 132 DGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
+ I + + R L+I + D G Y N+ G ++ L V
Sbjct: 3001 NEQPIKLNTNTLIVPGG---RTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTV 3052
Score = 39.1 bits (87), Expect = 0.012
Identities = 35/144 (24%), Positives = 53/144 (36%), Gaps = 13/144 (9%)
Query: 43 DDGTARLKIKQVTAEDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYP 102
+ + L I +VT DEG Y C A + G ++ V S P P P
Sbjct: 478 ESASVNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDV------SEP-----PPVIQVP 526
Query: 103 FNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIE 162
N V GE C + +W ++ + + ++ + LE+ V
Sbjct: 527 NNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLS--LELKSVKFN 584
Query: 163 DVGIYRITVENELGRAEASARLEV 186
D G Y V +E G + AS L V
Sbjct: 585 DAGEYHCMVSSEGGSSAASVFLTV 608
>AL133553-2|CAI17858.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-174L6 on chromosome 1. ).
Length = 5635
Score = 75.4 bits (177), Expect = 1e-13
Identities = 55/183 (30%), Positives = 78/183 (42%), Gaps = 10/183 (5%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G V C+ +GNP P + W E+I + S+ DG+ L + E+ G Y C
Sbjct: 994 EGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGS--LYVVSPGGEESGEYVC 1051
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
A+N G AK L VY R+ R ++ P V GE VT C VK P
Sbjct: 1052 TATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQD---KPVEISVLAGEEVTLPCEVKSLPP 1108
Query: 125 PWASWDKDGSIITP-SARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
P +W K+ +I+P S R T ++I E D G+Y N G + +
Sbjct: 1109 PIITWAKETQLISPFSPRHTFLPSGS----MKITETRTSDSGMYLCVATNIAGNVTQAVK 1164
Query: 184 LEV 186
L V
Sbjct: 1165 LNV 1167
Score = 74.5 bits (175), Expect = 3e-13
Identities = 48/178 (26%), Positives = 75/178 (42%), Gaps = 13/178 (7%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
V +C G P+P I W + + G L+I + ED G YTC A+N
Sbjct: 1844 VALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATN 1902
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G+ + + L V+ L G+ + N+ V V +C GNP P +
Sbjct: 1903 AAGETQQHIQLHVHEPPSLEDAGKML---------NETVLVSNPVQLECKAAGNPVPVIT 1953
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KD +++ S +T + + I++I+ I D GIY+ N G E L+V
Sbjct: 1954 WYKDNRLLSGSTSMTFLNRGQ---IIDIESAQISDAGIYKCVAINSAGATELFYSLQV 2008
Score = 70.9 bits (166), Expect = 3e-12
Identities = 60/180 (33%), Positives = 80/180 (44%), Gaps = 20/180 (11%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+ + C+ TG P P + W +I A F+S +G + L I++V+ ED GTY C
Sbjct: 4274 GEQLRLSCKATGIPLPKLTWTFNNNIIP--AHFDSV--NGHSELVIERVSKEDSGTYVCT 4329
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFY-TYPFNKVVEEGENVTFKCAVKGNPS 124
A N +G K A VY + P P F YP N + G N C VKG+P+
Sbjct: 4330 AENSVGFVK--AIGFVY----VKEP-----PVFKGDYPSNWIEPLGGNAILNCEVKGDPT 4378
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
P W++ G I S RI ++ L I ED G Y NE G E S L
Sbjct: 4379 PTIQWNRKGVDIEISHRI----RQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSL 4434
Score = 68.5 bits (160), Expect = 2e-11
Identities = 47/179 (26%), Positives = 78/179 (43%), Gaps = 13/179 (7%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
++ EC+ G P P I W+ + I + ++ Y D L I + D TYTC +N
Sbjct: 1565 IKLECETRGLPMPAITWYKDGQPIMSSS--QALYIDKGQYLHIPRAQVSDSATYTCHVAN 1622
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G A+ + + VY + +A P NK V ++T +C GNPSP +
Sbjct: 1623 VAGTAEKSFHVDVYVPPMIEG---NLAT-----PLNKQVVIAHSLTLECKAAGNPSPILT 1674
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVI 187
W KDG + + I ++ + + I+ E+ D G Y + G E ++V+
Sbjct: 1675 WLKDGVPVKANDNIRIEAGGKKLEIMSAQEI---DRGQYICVATSVAGEKEIKYEVDVL 1730
Score = 67.7 bits (158), Expect = 3e-11
Identities = 43/182 (23%), Positives = 79/182 (43%), Gaps = 11/182 (6%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G+ + C+ +G P P++ W + + G +L+I D Y+C
Sbjct: 2210 EGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSC 2269
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
ASN G AK L VY +++ G ++P +V G++++ +C V+G P
Sbjct: 2270 VASNVAGTAKKEYNLQVYIRPTITNSG--------SHPTEIIVTRGKSISLECEVQGIPP 2321
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
P +W KDG + + + + ++ IL++ + + D G Y N G + L
Sbjct: 2322 PTVTWMKDGHPLIKAKGVEILDEG---HILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDL 2378
Query: 185 EV 186
V
Sbjct: 2379 SV 2380
Score = 66.5 bits (155), Expect = 7e-11
Identities = 53/174 (30%), Positives = 73/174 (41%), Gaps = 16/174 (9%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFE-SSYDD-GTARLKIKQVTAEDEGTYT 63
G V C V G P+P I+W + F SS T L I + A D+GTY
Sbjct: 807 GSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYI 866
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCA-VKGN 122
CEA N GK +S + V +AP P V EG+ +T C + GN
Sbjct: 867 CEAENQFGKIQSETTVTVTGL---------VAPLIGISPSVANVIEGQQLTLPCTLLAGN 917
Query: 123 PSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG 176
P P W K+ +++ + ITV+ L I+ V ++D G Y N G
Sbjct: 918 PIPERRWIKNSAMLLQNPYITVRSDGS----LHIERVQLQDGGEYTCVASNVAG 967
Score = 66.5 bits (155), Expect = 7e-11
Identities = 50/178 (28%), Positives = 71/178 (39%), Gaps = 13/178 (7%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
V ECQV G P PDI WF + + D D L +K D+G Y C SN
Sbjct: 1471 VALECQVKGTPFPDIHWFKDGKPL-FLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSN 1529
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
GK + L +Y + T + N +++ +C +G P P +
Sbjct: 1530 AAGKQAKDIKLTIYIPPSIKGGN---VTTDISVLINSLIK------LECETRGLPMPAIT 1580
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KDG I S++ +K + L I + D Y V N G AE S ++V
Sbjct: 1581 WYKDGQPIMSSSQALYIDKGQ---YLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDV 1635
Score = 65.7 bits (153), Expect = 1e-10
Identities = 46/178 (25%), Positives = 74/178 (41%), Gaps = 12/178 (6%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
+ C+V+G P PD+ W + I+ + + G L+I + D G YTC A N
Sbjct: 2982 ISLTCEVSGFPPPDLSWLKNEQPIK--LNTNTLIVPGGRTLQIIRAKVSDGGEYTCIAIN 3039
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G++K L VY + + V EG +V+ +C P P +
Sbjct: 3040 QAGESKKKFSLTVYVPPSIKDHDSESLSVVN-------VREGTSVSLECESNAVPPPVIT 3092
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W K+G +IT S + + + +L I + + D G Y N GR + + L V
Sbjct: 3093 WYKNGRMITESTHVEILADGQ---MLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNV 3147
Score = 65.3 bits (152), Expect = 2e-10
Identities = 52/182 (28%), Positives = 75/182 (41%), Gaps = 14/182 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
GD EC+ +G P P ++WF +R D LKI++ D G YTC
Sbjct: 716 GDITVMECKTSGIPPPQVKWFKGDLELRPSTFL--IIDPLLGLLKIQETQDLDAGDYTCV 773
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A N G+A L V SP P F P + +E G NVT C V+G P P
Sbjct: 774 AINEAGRATGKITLDV------GSP-----PVFIQEPADVSMEIGSNVTLPCYVQGYPEP 822
Query: 126 WASWDKDGSIITPSARITVKEKEEIMR-ILEIDEVSIEDVGIYRITVENELGRAEASARL 184
W + ++ S +V ++ L I + D G Y EN+ G+ ++ +
Sbjct: 823 TIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTV 882
Query: 185 EV 186
V
Sbjct: 883 TV 884
Score = 64.9 bits (151), Expect = 2e-10
Identities = 57/198 (28%), Positives = 82/198 (41%), Gaps = 19/198 (9%)
Query: 5 DGDTVEFECQV-TGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYT 63
+G + C + GNP P+ RW + ++ + + DG+ L I++V +D G YT
Sbjct: 903 EGQQLTLPCTLLAGNPIPERRWIKNSAMLLQ-NPYITVRSDGS--LHIERVQLQDGGEYT 959
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
C ASN G +VV H G+Q+ T EG VT C GNP
Sbjct: 960 CVASNVAGTNNKTTSVVV-HVLPTIQHGQQILSTI----------EGIPVTLPCKASGNP 1008
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
P W K G +I+ S + K L + E+ G Y T N G A+ +
Sbjct: 1009 KPSVIWSKKGELISTS---SAKFSAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKVQ 1065
Query: 184 LEVITRSGKFYGGLRAYS 201
L V R + +G R S
Sbjct: 1066 LTVYVRP-RVFGDQRGLS 1082
Score = 63.7 bits (148), Expect = 5e-10
Identities = 53/181 (29%), Positives = 70/181 (38%), Gaps = 17/181 (9%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G V C TG P P I W I + + DGT L IK +D G Y C
Sbjct: 626 GSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMT-SDGT--LFIKNAAPKDAGIYGCL 682
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
ASN G K N+ L R + AP +V G+ +C G P P
Sbjct: 683 ASNSAGTDKQNSTL-----RYIE------APKLMVVQSELLVALGDITVMECKTSGIPPP 731
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
W K + PS + + + ++ +L+I E D G Y NE GRA L+
Sbjct: 732 QVKWFKGDLELRPSTFLII---DPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLD 788
Query: 186 V 186
V
Sbjct: 789 V 789
Score = 63.7 bits (148), Expect = 5e-10
Identities = 47/178 (26%), Positives = 78/178 (43%), Gaps = 14/178 (7%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
+E +C VTG+P P I W ++I + F+ + +L I Q + G Y C A+N
Sbjct: 1752 LELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNG--RKLVIAQAQVSNTGLYRCMAAN 1809
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G K + V+ + S G +VV + + V +C G P+P +
Sbjct: 1810 TAGDHKKEFEVTVHVPPTIKSSGLS----------ERVVVKYKPVALQCIANGIPNPSIT 1859
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KD + +A+ +K + R+L+I + +ED G Y N G + +L V
Sbjct: 1860 WLKDDQPVN-TAQGNLKIQSS-GRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHV 1915
Score = 63.3 bits (147), Expect = 6e-10
Identities = 47/182 (25%), Positives = 73/182 (40%), Gaps = 13/182 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G ++ EC+V G P P + W + E D+G L++K + D G Y C
Sbjct: 2307 GKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEI-LDEGHI-LQLKNIHVSDTGRYVCV 2364
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A N G L V+ + R P N V E +V+ C G P P
Sbjct: 2365 AVNVAGMTDKKYDLSVHAPPSIIGNHRS--------PENISVVEKNSVSLTCEASGIPLP 2416
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
+W KDG ++ S + + ++R++ + ++ED G Y V N G L
Sbjct: 2417 SITWFKDGWPVSLSNSVRILSGGRMLRLM---QTTMEDAGQYTCVVRNAAGEERKIFGLS 2473
Query: 186 VI 187
V+
Sbjct: 2474 VL 2475
Score = 62.9 bits (146), Expect = 8e-10
Identities = 50/179 (27%), Positives = 71/179 (39%), Gaps = 13/179 (7%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
+EF C G P P I+W H + S +DGT L I VT D G Y C A N
Sbjct: 1284 IEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGTL-LVIASVTPYDNGEYICVAVN 1342
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G + L V H + Q+ N V + C V+G PSP
Sbjct: 1343 EAGTTERKYNLKV-HVPPVIKDKEQVT--------NVSVLLNQLTNLFCEVEGTPSPIIM 1393
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVI 187
W KD +T S+ I +I+++ + ED G Y N G ++ ++V+
Sbjct: 1394 WYKDNVQVTESSTIQTVNNGKILKLF---RATPEDAGRYSCKAINIAGTSQKYFNIDVL 1449
Score = 62.1 bits (144), Expect = 1e-09
Identities = 52/182 (28%), Positives = 71/182 (39%), Gaps = 12/182 (6%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G V+ C G P P I W + + S DGT L I Q T D G YTC
Sbjct: 1185 GQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGT--LSIDQATPSDAGIYTCV 1242
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A+N G ++ L V + + P + T +V + + F C KG P P
Sbjct: 1243 ATNIAGTDETEITLHVQEPPTVED----LEPPYNTTFQERVANQ--RIEFPCPAKGTPKP 1296
Query: 126 WASWDKDGSIIT-PSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
W +G +T I++ E +L I V+ D G Y NE G E L
Sbjct: 1297 TIKWLHNGRELTGREPGISILEDG---TLLVIASVTPYDNGEYICVAVNEAGTTERKYNL 1353
Query: 185 EV 186
+V
Sbjct: 1354 KV 1355
Score = 61.7 bits (143), Expect = 2e-09
Identities = 47/181 (25%), Positives = 68/181 (37%), Gaps = 16/181 (8%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+ V C+V P P I W ++I + + G+ +KI + D G Y C
Sbjct: 1094 GEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGS--MKITETRTSDSGMYLCV 1151
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A+N G L V+ + P P + V+ G+ V C +G P P
Sbjct: 1152 ATNIAGNVTQAVKLNVH-----------VPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLP 1200
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
+W K GS + V + L ID+ + D GIY N G E L
Sbjct: 1201 VITWSKGGSTMLVDGEHHVSNPD---GTLSIDQATPSDAGIYTCVATNIAGTDETEITLH 1257
Query: 186 V 186
V
Sbjct: 1258 V 1258
Score = 61.3 bits (142), Expect = 3e-09
Identities = 50/178 (28%), Positives = 64/178 (35%), Gaps = 10/178 (5%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
V C TG P P I W + I + E G ++L+I + D G YTC ASN
Sbjct: 3169 VTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASN 3228
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
GKA+ Y+ + P P + V GENV C G P+P
Sbjct: 3229 MEGKAQK------YYFLSIQVPPSVAGAEI---PSDVSVLLGENVELVCNANGIPTPLIQ 3279
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KDG I ++ L I D G Y N G + L V
Sbjct: 3280 WLKDGKPIASGETERIRVSAN-GSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNV 3336
Score = 60.1 bits (139), Expect = 6e-09
Identities = 48/168 (28%), Positives = 73/168 (43%), Gaps = 18/168 (10%)
Query: 13 CQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLGK 72
C G P P I W ++ + ++ G L ++ V ED G YTC A+N G+
Sbjct: 4190 CVADGIPTPAINWKKDNVLLANLLGKYTAEPYG--ELILENVVLEDSGFYTCVANNAAGE 4247
Query: 73 AKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKD 132
L V+ + PTF P + + +GE + C G P P +W +
Sbjct: 4248 DTHTVSLTVH-----------VLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFN 4296
Query: 133 GSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEA 180
+II P+ +V E++ I+ VS ED G Y T EN +G +A
Sbjct: 4297 NNII-PAHFDSVNGHSELV----IERVSKEDSGTYVCTAENSVGFVKA 4339
Score = 58.0 bits (134), Expect = 2e-08
Identities = 44/175 (25%), Positives = 75/175 (42%), Gaps = 15/175 (8%)
Query: 13 CQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLGK 72
C+V G P P I W+ + + + ++ ++G LK+ + T ED G Y+C+A N G
Sbjct: 1382 CEVEGTPSPIIMWYKDNVQVTESSTIQT-VNNGKI-LKLFRATPEDAGRYSCKAINIAGT 1439
Query: 73 AKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKD 132
++ Y + P + F P V +V +C VKG P P W KD
Sbjct: 1440 SQK------YFNIDVLVPPTIIGTNF---PNEVSVVLNRDVALECQVKGTPFPDIHWFKD 1490
Query: 133 GS-IITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
G + + + ++ + +L + D G Y+ TV N G+ +L +
Sbjct: 1491 GKPLFLGDPNVELLDRGQ---VLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTI 1542
Score = 57.6 bits (133), Expect = 3e-08
Identities = 49/176 (27%), Positives = 69/176 (39%), Gaps = 15/176 (8%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G +V EC+ P P I W+ +I + E D L IK+ D G Y C
Sbjct: 3073 EGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADG--QMLHIKKAEVSDTGQYVC 3130
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGEN-VTFKCAVKGNP 123
A N G+ N L VY + P R++ +VE N VT C G P
Sbjct: 3131 RAINVAGRDDKNFHLNVYVPPSIEGPEREV-----------IVETISNPVTLTCDATGIP 3179
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAE 179
P +W K+ I S + V+ + L+I D G Y N G+A+
Sbjct: 3180 PPTIAWLKNHKRIENSDSLEVRILSGGSK-LQIARSQHSDSGNYTCIASNMEGKAQ 3234
Score = 57.2 bits (132), Expect = 4e-08
Identities = 54/200 (27%), Positives = 74/200 (37%), Gaps = 29/200 (14%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSY---DDGTARLKIKQVTAEDEGTY 62
G C+V G+P P I+W R D E S+ G L I ED G Y
Sbjct: 4364 GGNAILNCEVKGDPTPTIQWN------RKGVDIEISHRIRQLGNGSLAIYGTVNEDAGDY 4417
Query: 63 TCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGN 122
TC A+N G + + L L SP P P V+ G + C G
Sbjct: 4418 TCVATNEAGVVERSMSLT------LQSP-----PIITLEPVETVINAGGKIILNCQATGE 4466
Query: 123 PSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASA 182
P P +W + G I+ R+ V L I + ED + N +G
Sbjct: 4467 PQPTITWSRQGHSISWDDRVNVLSNNS----LYIADAQKEDTSEFECVARNLMG--SVLV 4520
Query: 183 RLEVITRSGKFYGGLRAYSA 202
R+ VI + +GG +SA
Sbjct: 4521 RVPVIV---QVHGGFSQWSA 4537
Score = 56.8 bits (131), Expect = 6e-08
Identities = 48/178 (26%), Positives = 69/178 (38%), Gaps = 17/178 (9%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
+ C+ G P PDI W I + + G+ L+I V D G YTC A+N
Sbjct: 4096 ITLSCEADGLPPPDITWHKDGRAIVESIR-QRVLSSGS--LQIAFVQPGDAGHYTCMAAN 4152
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G + ++ L V+ R+ S YT V E C G P+P +
Sbjct: 4153 VAGSSSTSTKLTVHVPPRIRS-----TEGHYT------VNENSQAILPCVADGIPTPAIN 4201
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KD ++ A + K E L ++ V +ED G Y N G + L V
Sbjct: 4202 WKKDNVLL---ANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHTVSLTV 4256
Score = 56.4 bits (130), Expect = 7e-08
Identities = 46/181 (25%), Positives = 70/181 (38%), Gaps = 11/181 (6%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+ VE C G P P I+W + I + L I D G YTC
Sbjct: 3261 GENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCV 3320
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A+N G+ L VY T + + A T +V+ N+ +C G P P
Sbjct: 3321 ATNPAGEEDRIFNLNVYVTPTIRG-NKDEAEKLMT-----LVDTSINI--ECRATGTPPP 3372
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
+W K+G + S+ I + +++RI+ + DV +Y N G L+
Sbjct: 3373 QINWLKNGLPLPLSSHIRLLAAGQVIRIV---RAQVSDVAVYTCVASNRAGVDNKHYNLQ 3429
Query: 186 V 186
V
Sbjct: 3430 V 3430
Score = 56.4 bits (130), Expect = 7e-08
Identities = 49/174 (28%), Positives = 63/174 (36%), Gaps = 17/174 (9%)
Query: 13 CQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLGK 72
C+ TG P P I W + + G L+I + ED GTY C A N G
Sbjct: 4009 CEATGTPSPFITWQKEGINVNTSGRNHAVLPSGG--LQISRAVREDAGTYMCVAQNPAGT 4066
Query: 73 AKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKD 132
A L V Q+ P + V+ + +T C G P P +W KD
Sbjct: 4067 ALGKIKLNV-----------QVPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKD 4115
Query: 133 GSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
G I S R V L+I V D G Y N G + S +L V
Sbjct: 4116 GRAIVESIRQRVLSSGS----LQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTV 4165
Score = 56.0 bits (129), Expect = 1e-07
Identities = 45/180 (25%), Positives = 72/180 (40%), Gaps = 14/180 (7%)
Query: 8 TVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEAS 67
++ EC+ TG P P I W + + R+ QV+ D YTC AS
Sbjct: 3359 SINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVS--DVAVYTCVAS 3416
Query: 68 NCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWA 127
N G + L V+ + + M T V +G + + C G P+P
Sbjct: 3417 NRAGVDNKHYNLQVFAPPNMDN---SMGTEEIT------VLKGSSTSMACITDGTPAPSM 3467
Query: 128 SWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVI 187
+W +DG + A +TV ++++L+ + ED G Y NE G L+V+
Sbjct: 3468 AWLRDGQPLGLDAHLTVSTHGMVLQLLKAE---TEDSGKYTCIASNEAGEVSKHFILKVL 3524
Score = 55.6 bits (128), Expect = 1e-07
Identities = 48/183 (26%), Positives = 70/183 (38%), Gaps = 16/183 (8%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
VE CQ P P + W + S + + LKI+ +D G YTCEA+N
Sbjct: 2121 VELLCQSDAIPPPTLTWLKDGHPLLKKPGL--SISENRSVLKIEDAQVQDTGRYTCEATN 2178
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
GK + N + ++ + T V EG ++ C G P P
Sbjct: 2179 VAGKTEKNYNVNIWVPPNIGGSDELTQLT---------VIEGNLISLLCESSGIPPPNLI 2229
Query: 129 WDKDGS-IITPS-ARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W K GS ++T S R+ + R L+I D +Y N G A+ L+V
Sbjct: 2230 WKKKGSPVLTDSMGRVRILSGG---RQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQV 2286
Query: 187 ITR 189
R
Sbjct: 2287 YIR 2289
Score = 55.2 bits (127), Expect = 2e-07
Identities = 48/180 (26%), Positives = 66/180 (36%), Gaps = 14/180 (7%)
Query: 7 DTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEA 66
++V C+ +G P P I WF + G L++ Q T ED G YTC
Sbjct: 2402 NSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRIL--SGGRMLRLMQTTMEDAGQYTCVV 2459
Query: 67 SNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPW 126
N G+ + ++ L P T V+E ++VT C V GNP P
Sbjct: 2460 RNAAGEERK-----IFGLSVLVPPHIVGENTLEDVK----VKEKQSVTLTCEVTGNPVPE 2510
Query: 127 ASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
+W KDG P R L+I V + G Y + G S L V
Sbjct: 2511 ITWHKDGQ---PLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNV 2567
Score = 54.4 bits (125), Expect = 3e-07
Identities = 43/169 (25%), Positives = 67/169 (39%), Gaps = 11/169 (6%)
Query: 8 TVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEAS 67
+V C+VTGNP P+I W + +++ D G L+I V G YTC AS
Sbjct: 2496 SVTLTCEVTGNPVPEITWHKDGQPLQE--DEAHHIISGGRFLQITNVQVPHTGRYTCLAS 2553
Query: 68 NCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWA 127
+ G + L V+ + ++ G P T N + C P
Sbjct: 2554 SPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILN------SPTSLVCEAYSYPPATI 2607
Query: 128 SWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG 176
+W KDG+ + + I + ++IL E ++ G Y NE G
Sbjct: 2608 TWFKDGTPLESNRNIRILPGGRTLQILNAQE---DNAGRYSCVATNEAG 2653
Score = 54.4 bits (125), Expect = 3e-07
Identities = 43/173 (24%), Positives = 72/173 (41%), Gaps = 10/173 (5%)
Query: 7 DTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEA 66
+T+ EC+ P + W+ + ++ + + T L+IK+ D G YTC A
Sbjct: 2690 NTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHT--LQIKEAQISDTGRYTCVA 2747
Query: 67 SNCLGKAKSNACL---VVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
SN G+ + + + V ++L G M T V+ ++ C P
Sbjct: 2748 SNIAGEDELDFDVNIQVPPSFQKLWEIG-NMLDTGRNGEAKDVIINNP-ISLYCETNAAP 2805
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG 176
P +W KDG +T S ++ + R+L+I +ED G Y NE G
Sbjct: 2806 PPTLTWYKDGHPLTSSDKVLILPGG---RVLQIPRAKVEDAGRYTCVAVNEAG 2855
Score = 53.6 bits (123), Expect = 5e-07
Identities = 40/178 (22%), Positives = 66/178 (37%), Gaps = 15/178 (8%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
V EC+ G P P + W + ++ G L + D G YTC A N
Sbjct: 2029 VRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRI-LALTSAQISDTGRYTCVAVN 2087
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G+ + + L VY + P N V + V C P P +
Sbjct: 2088 AAGEKQRDIDLRVY-----------VPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLT 2136
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KDG + +++ E +L+I++ ++D G Y N G+ E + + +
Sbjct: 2137 WLKDGHPLLKKPGLSISENRS---VLKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNI 2191
Score = 52.8 bits (121), Expect = 9e-07
Identities = 46/179 (25%), Positives = 67/179 (37%), Gaps = 18/179 (10%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
V EC+ P P I W E ++ A G L+I D YTC ASN
Sbjct: 3639 VTLECKSDAVPPPVITWLRNGERLQ--ATPRVRILSGGRYLQINNADLGDTANYTCVASN 3696
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
GK L V + P P + V+ ++ +C +G P+P +
Sbjct: 3697 IAGKTTREFILTV-----------NVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRIT 3745
Query: 129 WDKDGSIITPS-ARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KDG+++ + AR ++ E L I + D G Y N G L+V
Sbjct: 3746 WRKDGAVLAGNHARYSILEN----GFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQV 3800
Score = 52.0 bits (119), Expect = 2e-06
Identities = 47/178 (26%), Positives = 68/178 (38%), Gaps = 12/178 (6%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
+ C+ P P + W+ + +D G L+I + ED G YTC A N
Sbjct: 2795 ISLYCETNAAPPPTLTWYKDGHPLTS-SDKVLILPGGRV-LQIPRAKVEDAGRYTCVAVN 2852
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G+ + Y R L P + A + P V ++ +C G+P+P S
Sbjct: 2853 EAGEDS-----LQYDVRVLVPPIIKGANS--DLPEEVTVLVNKSALIECLSSGSPAPRNS 2905
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KDG + RIL+I I D+G Y EN G A+ L V
Sbjct: 2906 WQKDGQPLLEDDHHKFLSNG---RILQILNTQITDIGRYVCVAENTAGSAKKYFNLNV 2960
Score = 50.8 bits (116), Expect = 4e-06
Identities = 45/179 (25%), Positives = 68/179 (37%), Gaps = 17/179 (9%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
V+ EC+ GNP P I W+ ++ ++ + + I+ D G Y C A N
Sbjct: 1938 VQLECKAAGNPVPVITWYKDNRLLSGSTSM--TFLNRGQIIDIESAQISDAGIYKCVAIN 1995
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G + L V+ +S +A V V +C +G P+P +
Sbjct: 1996 SAGATELFYSLQVHVAPSISGSNNMVA-----------VVVNNPVRLECEARGIPAPSLT 2044
Query: 129 WDKDGSIITP-SARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KDGS ++ S + V RIL + I D G Y N G + L V
Sbjct: 2045 WLKDGSPVSSFSNGLQVLSGG---RILALTSAQISDTGRYTCVAVNAAGEKQRDIDLRV 2100
Score = 48.8 bits (111), Expect = 1e-05
Identities = 40/171 (23%), Positives = 68/171 (39%), Gaps = 18/171 (10%)
Query: 8 TVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEAS 67
++ EC+ GNP P + W ++ A+ + G +L+I D G Y C A+
Sbjct: 1658 SLTLECKAAGNPSPILTWLKDGVPVK--ANDNIRIEAGGKKLEIMSAQEIDRGQYICVAT 1715
Query: 68 NCLGKAKSNACLVVYHTRRLSSPGRQMA--PTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
+ G+ + + Y L P + +++ N ++E C V G+P P
Sbjct: 1716 SVAGEKE-----IKYEVDVLVPPAIEGGDETSYFIVMVNNLLE------LDCHVTGSPPP 1764
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG 176
W KDG +I + R L I + + + G+YR N G
Sbjct: 1765 TIMWLKDGQLIDERDGFKILLNG---RKLVIAQAQVSNTGLYRCMAANTAG 1812
Score = 47.6 bits (108), Expect = 3e-05
Identities = 43/174 (24%), Positives = 57/174 (32%), Gaps = 16/174 (9%)
Query: 13 CQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLGK 72
C +G P P I W + D G + Q+ G YTC A N G
Sbjct: 3918 CTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQLN--HAGRYTCVARNAAGS 3975
Query: 73 AKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKD 132
A + L V+ P P V + C G PSP+ +W K+
Sbjct: 3976 AHRHVTLHVHEP-----------PVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKE 4024
Query: 133 GSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
G + S R L+I ED G Y +N G A +L V
Sbjct: 4025 GINVNTSGR---NHAVLPSGGLQISRAVREDAGTYMCVAQNPAGTALGKIKLNV 4075
Score = 47.2 bits (107), Expect = 4e-05
Identities = 48/180 (26%), Positives = 67/180 (37%), Gaps = 24/180 (13%)
Query: 12 ECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLG 71
EC G P P I W V+ S ++G ++ VT D G Y C A+N G
Sbjct: 3733 ECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLHIQSAHVT--DTGRYLCMATNAAG 3790
Query: 72 KAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDK 131
+ L V H +PG P N V T C G P P +W K
Sbjct: 3791 TDRRRIDLQV-HVPPSIAPG----------PTNMTVIVNVQTTLACEATGIPKPSINWRK 3839
Query: 132 DGSIITPSARITVKEKEEIMRILE-----IDEVSIEDVGIYRITVENELGRAEASARLEV 186
+G + + V + + R+L I S++D Y TV N G + + L V
Sbjct: 3840 NGHL------LNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGDDKRTVDLTV 3893
Score = 46.8 bits (106), Expect = 6e-05
Identities = 38/171 (22%), Positives = 63/171 (36%), Gaps = 14/171 (8%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G + C G P P + W + + D + L++ + ED G YTC
Sbjct: 3450 GSSTSMACITDGTPAPSMAWLRDGQPLG--LDAHLTVSTHGMVLQLLKAETEDSGKYTCI 3507
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
ASN G+ + L V ++ + +V +T C G P+P
Sbjct: 3508 ASNEAGEVSKHFILKVLEPPHINGSEEHEE-------ISVIVNNPLELT--CIASGIPAP 3558
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG 176
+W KDG + + ++ E++R I +ED G Y + G
Sbjct: 3559 KMTWMKDGRPLPQTDQVQTLGGGEVLR---ISTAQVEDTGRYTCLASSPAG 3606
Score = 42.3 bits (95), Expect = 0.001
Identities = 41/176 (23%), Positives = 60/176 (34%), Gaps = 18/176 (10%)
Query: 13 CQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLGK 72
C+ TG P P I W ++ + S + L I + +D TY C +N G
Sbjct: 3825 CEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGD 3884
Query: 73 AKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKD 132
K L V Q+ P+ P + +V + C G P P W K+
Sbjct: 3885 DKRTVDLTV-----------QVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKN 3933
Query: 133 GSIITPSARITVKEKEEIMR--ILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
G + P + I+ +EI + G Y N G A L V
Sbjct: 3934 GIRLLPRG-----DGYRILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHV 3984
Score = 41.9 bits (94), Expect = 0.002
Identities = 38/167 (22%), Positives = 59/167 (35%), Gaps = 8/167 (4%)
Query: 13 CQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLGK 72
C+ P I WF + + G L+I ++ G Y+C A+N G+
Sbjct: 2597 CEAYSYPPATITWFKDGTPLESNRNIRIL--PGGRTLQILNAQEDNAGRYSCVATNEAGE 2654
Query: 73 AKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKD 132
+ + VY + + G P P ++ +T +C PS SW KD
Sbjct: 2655 MIKHYEVKVY-IPPIINKGDLWGPGLS--PKEVKIKVNNTLTLECEAYAIPSASLSWYKD 2711
Query: 133 GSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAE 179
G + + + L+I E I D G Y N G E
Sbjct: 2712 GQPLKSDDHVNIAANG---HTLQIKEAQISDTGRYTCVASNIAGEDE 2755
Score = 40.7 bits (91), Expect = 0.004
Identities = 36/169 (21%), Positives = 61/169 (36%), Gaps = 14/169 (8%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
+E C +G P P + W + ++ G L+I ED G YTC AS+
Sbjct: 3546 LELTCIASGIPAPKMTWMKDGRPLPQTDQVQTL--GGGEVLRISTAQVEDTGRYTCLASS 3603
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G + V+ ++ P + V VT +C P P +
Sbjct: 3604 PAGDDDKEYLVRVHVPPNIAGTDE---------PRDITVLRNRQVTLECKSDAVPPPVIT 3654
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGR 177
W ++G + + R+ + R L+I+ + D Y N G+
Sbjct: 3655 WLRNGERLQATPRVRILSGG---RYLQINNADLGDTANYTCVASNIAGK 3700
Score = 40.3 bits (90), Expect = 0.005
Identities = 34/139 (24%), Positives = 52/139 (37%), Gaps = 15/139 (10%)
Query: 49 LKIKQVTAEDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVE 108
L++K V D G Y C S+ G + ++ L V Q P P N+
Sbjct: 576 LELKSVKFNDAGEYHCMVSSEGGSSAASVFLTV-----------QEPPKVTVMPKNQSFT 624
Query: 109 EGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYR 168
G V+ C+ G P P +W + I S R + + I + +D GIY
Sbjct: 625 GGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGTLF----IKNAAPKDAGIYG 680
Query: 169 ITVENELGRAEASARLEVI 187
N G + ++ L I
Sbjct: 681 CLASNSAGTDKQNSTLRYI 699
Score = 39.9 bits (89), Expect = 0.007
Identities = 43/175 (24%), Positives = 63/175 (36%), Gaps = 15/175 (8%)
Query: 12 ECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLG 71
EC +G+P P W + + + D +G L+I D G Y C A N G
Sbjct: 2893 ECLSSGSPAPRNSWQKDGQPLLE-DDHHKFLSNGRI-LQILNTQITDIGRYVCVAENTAG 2950
Query: 72 KAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDK 131
AK L V+ + P + N V ++ C V G P P SW K
Sbjct: 2951 SAKKYFNLNVHVPPSVIGPKSE----------NLTVVVNNFISLTCEVSGFPPPDLSWLK 3000
Query: 132 DGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
+ I + + R L+I + D G Y N+ G ++ L V
Sbjct: 3001 NEQPIKLNTNTLIVPGG---RTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTV 3052
Score = 39.1 bits (87), Expect = 0.012
Identities = 35/144 (24%), Positives = 53/144 (36%), Gaps = 13/144 (9%)
Query: 43 DDGTARLKIKQVTAEDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYP 102
+ + L I +VT DEG Y C A + G ++ V S P P P
Sbjct: 478 ESASVNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDV------SEP-----PPVIQVP 526
Query: 103 FNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIE 162
N V GE C + +W ++ + + ++ + LE+ V
Sbjct: 527 NNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLS--LELKSVKFN 584
Query: 163 DVGIYRITVENELGRAEASARLEV 186
D G Y V +E G + AS L V
Sbjct: 585 DAGEYHCMVSSEGGSSAASVFLTV 608
>AL133515-1|CAI17853.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-153O3 on chromosome 1. ).
Length = 5635
Score = 75.4 bits (177), Expect = 1e-13
Identities = 55/183 (30%), Positives = 78/183 (42%), Gaps = 10/183 (5%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G V C+ +GNP P + W E+I + S+ DG+ L + E+ G Y C
Sbjct: 994 EGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGS--LYVVSPGGEESGEYVC 1051
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
A+N G AK L VY R+ R ++ P V GE VT C VK P
Sbjct: 1052 TATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQD---KPVEISVLAGEEVTLPCEVKSLPP 1108
Query: 125 PWASWDKDGSIITP-SARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
P +W K+ +I+P S R T ++I E D G+Y N G + +
Sbjct: 1109 PIITWAKETQLISPFSPRHTFLPSGS----MKITETRTSDSGMYLCVATNIAGNVTQAVK 1164
Query: 184 LEV 186
L V
Sbjct: 1165 LNV 1167
Score = 74.5 bits (175), Expect = 3e-13
Identities = 48/178 (26%), Positives = 75/178 (42%), Gaps = 13/178 (7%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
V +C G P+P I W + + G L+I + ED G YTC A+N
Sbjct: 1844 VALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATN 1902
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G+ + + L V+ L G+ + N+ V V +C GNP P +
Sbjct: 1903 AAGETQQHIQLHVHEPPSLEDAGKML---------NETVLVSNPVQLECKAAGNPVPVIT 1953
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KD +++ S +T + + I++I+ I D GIY+ N G E L+V
Sbjct: 1954 WYKDNRLLSGSTSMTFLNRGQ---IIDIESAQISDAGIYKCVAINSAGATELFYSLQV 2008
Score = 70.9 bits (166), Expect = 3e-12
Identities = 60/180 (33%), Positives = 80/180 (44%), Gaps = 20/180 (11%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+ + C+ TG P P + W +I A F+S +G + L I++V+ ED GTY C
Sbjct: 4274 GEQLRLSCKATGIPLPKLTWTFNNNIIP--AHFDSV--NGHSELVIERVSKEDSGTYVCT 4329
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFY-TYPFNKVVEEGENVTFKCAVKGNPS 124
A N +G K A VY + P P F YP N + G N C VKG+P+
Sbjct: 4330 AENSVGFVK--AIGFVY----VKEP-----PVFKGDYPSNWIEPLGGNAILNCEVKGDPT 4378
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
P W++ G I S RI ++ L I ED G Y NE G E S L
Sbjct: 4379 PTIQWNRKGVDIEISHRI----RQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSL 4434
Score = 68.5 bits (160), Expect = 2e-11
Identities = 47/179 (26%), Positives = 78/179 (43%), Gaps = 13/179 (7%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
++ EC+ G P P I W+ + I + ++ Y D L I + D TYTC +N
Sbjct: 1565 IKLECETRGLPMPAITWYKDGQPIMSSS--QALYIDKGQYLHIPRAQVSDSATYTCHVAN 1622
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G A+ + + VY + +A P NK V ++T +C GNPSP +
Sbjct: 1623 VAGTAEKSFHVDVYVPPMIEG---NLAT-----PLNKQVVIAHSLTLECKAAGNPSPILT 1674
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVI 187
W KDG + + I ++ + + I+ E+ D G Y + G E ++V+
Sbjct: 1675 WLKDGVPVKANDNIRIEAGGKKLEIMSAQEI---DRGQYICVATSVAGEKEIKYEVDVL 1730
Score = 67.7 bits (158), Expect = 3e-11
Identities = 43/182 (23%), Positives = 79/182 (43%), Gaps = 11/182 (6%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G+ + C+ +G P P++ W + + G +L+I D Y+C
Sbjct: 2210 EGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSC 2269
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
ASN G AK L VY +++ G ++P +V G++++ +C V+G P
Sbjct: 2270 VASNVAGTAKKEYNLQVYIRPTITNSG--------SHPTEIIVTRGKSISLECEVQGIPP 2321
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
P +W KDG + + + + ++ IL++ + + D G Y N G + L
Sbjct: 2322 PTVTWMKDGHPLIKAKGVEILDEG---HILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDL 2378
Query: 185 EV 186
V
Sbjct: 2379 SV 2380
Score = 66.5 bits (155), Expect = 7e-11
Identities = 53/174 (30%), Positives = 73/174 (41%), Gaps = 16/174 (9%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFE-SSYDD-GTARLKIKQVTAEDEGTYT 63
G V C V G P+P I+W + F SS T L I + A D+GTY
Sbjct: 807 GSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYI 866
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCA-VKGN 122
CEA N GK +S + V +AP P V EG+ +T C + GN
Sbjct: 867 CEAENQFGKIQSETTVTVTGL---------VAPLIGISPSVANVIEGQQLTLPCTLLAGN 917
Query: 123 PSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG 176
P P W K+ +++ + ITV+ L I+ V ++D G Y N G
Sbjct: 918 PIPERRWIKNSAMLLQNPYITVRSDGS----LHIERVQLQDGGEYTCVASNVAG 967
Score = 66.5 bits (155), Expect = 7e-11
Identities = 50/178 (28%), Positives = 71/178 (39%), Gaps = 13/178 (7%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
V ECQV G P PDI WF + + D D L +K D+G Y C SN
Sbjct: 1471 VALECQVKGTPFPDIHWFKDGKPL-FLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSN 1529
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
GK + L +Y + T + N +++ +C +G P P +
Sbjct: 1530 AAGKQAKDIKLTIYIPPSIKGGN---VTTDISVLINSLIK------LECETRGLPMPAIT 1580
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KDG I S++ +K + L I + D Y V N G AE S ++V
Sbjct: 1581 WYKDGQPIMSSSQALYIDKGQ---YLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDV 1635
Score = 65.7 bits (153), Expect = 1e-10
Identities = 46/178 (25%), Positives = 74/178 (41%), Gaps = 12/178 (6%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
+ C+V+G P PD+ W + I+ + + G L+I + D G YTC A N
Sbjct: 2982 ISLTCEVSGFPPPDLSWLKNEQPIK--LNTNTLIVPGGRTLQIIRAKVSDGGEYTCIAIN 3039
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G++K L VY + + V EG +V+ +C P P +
Sbjct: 3040 QAGESKKKFSLTVYVPPSIKDHDSESLSVVN-------VREGTSVSLECESNAVPPPVIT 3092
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W K+G +IT S + + + +L I + + D G Y N GR + + L V
Sbjct: 3093 WYKNGRMITESTHVEILADGQ---MLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNV 3147
Score = 65.3 bits (152), Expect = 2e-10
Identities = 52/182 (28%), Positives = 75/182 (41%), Gaps = 14/182 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
GD EC+ +G P P ++WF +R D LKI++ D G YTC
Sbjct: 716 GDITVMECKTSGIPPPQVKWFKGDLELRPSTFL--IIDPLLGLLKIQETQDLDAGDYTCV 773
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A N G+A L V SP P F P + +E G NVT C V+G P P
Sbjct: 774 AINEAGRATGKITLDV------GSP-----PVFIQEPADVSMEIGSNVTLPCYVQGYPEP 822
Query: 126 WASWDKDGSIITPSARITVKEKEEIMR-ILEIDEVSIEDVGIYRITVENELGRAEASARL 184
W + ++ S +V ++ L I + D G Y EN+ G+ ++ +
Sbjct: 823 TIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTV 882
Query: 185 EV 186
V
Sbjct: 883 TV 884
Score = 64.9 bits (151), Expect = 2e-10
Identities = 57/198 (28%), Positives = 82/198 (41%), Gaps = 19/198 (9%)
Query: 5 DGDTVEFECQV-TGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYT 63
+G + C + GNP P+ RW + ++ + + DG+ L I++V +D G YT
Sbjct: 903 EGQQLTLPCTLLAGNPIPERRWIKNSAMLLQ-NPYITVRSDGS--LHIERVQLQDGGEYT 959
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
C ASN G +VV H G+Q+ T EG VT C GNP
Sbjct: 960 CVASNVAGTNNKTTSVVV-HVLPTIQHGQQILSTI----------EGIPVTLPCKASGNP 1008
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
P W K G +I+ S + K L + E+ G Y T N G A+ +
Sbjct: 1009 KPSVIWSKKGELISTS---SAKFSAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKVQ 1065
Query: 184 LEVITRSGKFYGGLRAYS 201
L V R + +G R S
Sbjct: 1066 LTVYVRP-RVFGDQRGLS 1082
Score = 63.7 bits (148), Expect = 5e-10
Identities = 53/181 (29%), Positives = 70/181 (38%), Gaps = 17/181 (9%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G V C TG P P I W I + + DGT L IK +D G Y C
Sbjct: 626 GSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMT-SDGT--LFIKNAAPKDAGIYGCL 682
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
ASN G K N+ L R + AP +V G+ +C G P P
Sbjct: 683 ASNSAGTDKQNSTL-----RYIE------APKLMVVQSELLVALGDITVMECKTSGIPPP 731
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
W K + PS + + + ++ +L+I E D G Y NE GRA L+
Sbjct: 732 QVKWFKGDLELRPSTFLII---DPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLD 788
Query: 186 V 186
V
Sbjct: 789 V 789
Score = 63.7 bits (148), Expect = 5e-10
Identities = 47/178 (26%), Positives = 78/178 (43%), Gaps = 14/178 (7%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
+E +C VTG+P P I W ++I + F+ + +L I Q + G Y C A+N
Sbjct: 1752 LELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNG--RKLVIAQAQVSNTGLYRCMAAN 1809
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G K + V+ + S G +VV + + V +C G P+P +
Sbjct: 1810 TAGDHKKEFEVTVHVPPTIKSSGLS----------ERVVVKYKPVALQCIANGIPNPSIT 1859
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KD + +A+ +K + R+L+I + +ED G Y N G + +L V
Sbjct: 1860 WLKDDQPVN-TAQGNLKIQSS-GRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHV 1915
Score = 63.3 bits (147), Expect = 6e-10
Identities = 47/182 (25%), Positives = 73/182 (40%), Gaps = 13/182 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G ++ EC+V G P P + W + E D+G L++K + D G Y C
Sbjct: 2307 GKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEI-LDEGHI-LQLKNIHVSDTGRYVCV 2364
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A N G L V+ + R P N V E +V+ C G P P
Sbjct: 2365 AVNVAGMTDKKYDLSVHAPPSIIGNHRS--------PENISVVEKNSVSLTCEASGIPLP 2416
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
+W KDG ++ S + + ++R++ + ++ED G Y V N G L
Sbjct: 2417 SITWFKDGWPVSLSNSVRILSGGRMLRLM---QTTMEDAGQYTCVVRNAAGEERKIFGLS 2473
Query: 186 VI 187
V+
Sbjct: 2474 VL 2475
Score = 62.9 bits (146), Expect = 8e-10
Identities = 50/179 (27%), Positives = 71/179 (39%), Gaps = 13/179 (7%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
+EF C G P P I+W H + S +DGT L I VT D G Y C A N
Sbjct: 1284 IEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGTL-LVIASVTPYDNGEYICVAVN 1342
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G + L V H + Q+ N V + C V+G PSP
Sbjct: 1343 EAGTTERKYNLKV-HVPPVIKDKEQVT--------NVSVLLNQLTNLFCEVEGTPSPIIM 1393
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVI 187
W KD +T S+ I +I+++ + ED G Y N G ++ ++V+
Sbjct: 1394 WYKDNVQVTESSTIQTVNNGKILKLF---RATPEDAGRYSCKAINIAGTSQKYFNIDVL 1449
Score = 62.1 bits (144), Expect = 1e-09
Identities = 52/182 (28%), Positives = 71/182 (39%), Gaps = 12/182 (6%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G V+ C G P P I W + + S DGT L I Q T D G YTC
Sbjct: 1185 GQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGT--LSIDQATPSDAGIYTCV 1242
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A+N G ++ L V + + P + T +V + + F C KG P P
Sbjct: 1243 ATNIAGTDETEITLHVQEPPTVED----LEPPYNTTFQERVANQ--RIEFPCPAKGTPKP 1296
Query: 126 WASWDKDGSIIT-PSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
W +G +T I++ E +L I V+ D G Y NE G E L
Sbjct: 1297 TIKWLHNGRELTGREPGISILEDG---TLLVIASVTPYDNGEYICVAVNEAGTTERKYNL 1353
Query: 185 EV 186
+V
Sbjct: 1354 KV 1355
Score = 61.7 bits (143), Expect = 2e-09
Identities = 47/181 (25%), Positives = 68/181 (37%), Gaps = 16/181 (8%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+ V C+V P P I W ++I + + G+ +KI + D G Y C
Sbjct: 1094 GEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGS--MKITETRTSDSGMYLCV 1151
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A+N G L V+ + P P + V+ G+ V C +G P P
Sbjct: 1152 ATNIAGNVTQAVKLNVH-----------VPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLP 1200
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
+W K GS + V + L ID+ + D GIY N G E L
Sbjct: 1201 VITWSKGGSTMLVDGEHHVSNPD---GTLSIDQATPSDAGIYTCVATNIAGTDETEITLH 1257
Query: 186 V 186
V
Sbjct: 1258 V 1258
Score = 61.3 bits (142), Expect = 3e-09
Identities = 50/178 (28%), Positives = 64/178 (35%), Gaps = 10/178 (5%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
V C TG P P I W + I + E G ++L+I + D G YTC ASN
Sbjct: 3169 VTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASN 3228
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
GKA+ Y+ + P P + V GENV C G P+P
Sbjct: 3229 MEGKAQK------YYFLSIQVPPSVAGAEI---PSDVSVLLGENVELVCNANGIPTPLIQ 3279
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KDG I ++ L I D G Y N G + L V
Sbjct: 3280 WLKDGKPIASGETERIRVSAN-GSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNV 3336
Score = 60.1 bits (139), Expect = 6e-09
Identities = 48/168 (28%), Positives = 73/168 (43%), Gaps = 18/168 (10%)
Query: 13 CQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLGK 72
C G P P I W ++ + ++ G L ++ V ED G YTC A+N G+
Sbjct: 4190 CVADGIPTPAINWKKDNVLLANLLGKYTAEPYG--ELILENVVLEDSGFYTCVANNAAGE 4247
Query: 73 AKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKD 132
L V+ + PTF P + + +GE + C G P P +W +
Sbjct: 4248 DTHTVSLTVH-----------VLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFN 4296
Query: 133 GSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEA 180
+II P+ +V E++ I+ VS ED G Y T EN +G +A
Sbjct: 4297 NNII-PAHFDSVNGHSELV----IERVSKEDSGTYVCTAENSVGFVKA 4339
Score = 58.0 bits (134), Expect = 2e-08
Identities = 44/175 (25%), Positives = 75/175 (42%), Gaps = 15/175 (8%)
Query: 13 CQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLGK 72
C+V G P P I W+ + + + ++ ++G LK+ + T ED G Y+C+A N G
Sbjct: 1382 CEVEGTPSPIIMWYKDNVQVTESSTIQT-VNNGKI-LKLFRATPEDAGRYSCKAINIAGT 1439
Query: 73 AKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKD 132
++ Y + P + F P V +V +C VKG P P W KD
Sbjct: 1440 SQK------YFNIDVLVPPTIIGTNF---PNEVSVVLNRDVALECQVKGTPFPDIHWFKD 1490
Query: 133 GS-IITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
G + + + ++ + +L + D G Y+ TV N G+ +L +
Sbjct: 1491 GKPLFLGDPNVELLDRGQ---VLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTI 1542
Score = 57.6 bits (133), Expect = 3e-08
Identities = 49/176 (27%), Positives = 69/176 (39%), Gaps = 15/176 (8%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G +V EC+ P P I W+ +I + E D L IK+ D G Y C
Sbjct: 3073 EGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADG--QMLHIKKAEVSDTGQYVC 3130
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGEN-VTFKCAVKGNP 123
A N G+ N L VY + P R++ +VE N VT C G P
Sbjct: 3131 RAINVAGRDDKNFHLNVYVPPSIEGPEREV-----------IVETISNPVTLTCDATGIP 3179
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAE 179
P +W K+ I S + V+ + L+I D G Y N G+A+
Sbjct: 3180 PPTIAWLKNHKRIENSDSLEVRILSGGSK-LQIARSQHSDSGNYTCIASNMEGKAQ 3234
Score = 57.2 bits (132), Expect = 4e-08
Identities = 54/200 (27%), Positives = 74/200 (37%), Gaps = 29/200 (14%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSY---DDGTARLKIKQVTAEDEGTY 62
G C+V G+P P I+W R D E S+ G L I ED G Y
Sbjct: 4364 GGNAILNCEVKGDPTPTIQWN------RKGVDIEISHRIRQLGNGSLAIYGTVNEDAGDY 4417
Query: 63 TCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGN 122
TC A+N G + + L L SP P P V+ G + C G
Sbjct: 4418 TCVATNEAGVVERSMSLT------LQSP-----PIITLEPVETVINAGGKIILNCQATGE 4466
Query: 123 PSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASA 182
P P +W + G I+ R+ V L I + ED + N +G
Sbjct: 4467 PQPTITWSRQGHSISWDDRVNVLSNNS----LYIADAQKEDTSEFECVARNLMG--SVLV 4520
Query: 183 RLEVITRSGKFYGGLRAYSA 202
R+ VI + +GG +SA
Sbjct: 4521 RVPVIV---QVHGGFSQWSA 4537
Score = 56.8 bits (131), Expect = 6e-08
Identities = 48/178 (26%), Positives = 69/178 (38%), Gaps = 17/178 (9%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
+ C+ G P PDI W I + + G+ L+I V D G YTC A+N
Sbjct: 4096 ITLSCEADGLPPPDITWHKDGRAIVESIR-QRVLSSGS--LQIAFVQPGDAGHYTCMAAN 4152
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G + ++ L V+ R+ S YT V E C G P+P +
Sbjct: 4153 VAGSSSTSTKLTVHVPPRIRS-----TEGHYT------VNENSQAILPCVADGIPTPAIN 4201
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KD ++ A + K E L ++ V +ED G Y N G + L V
Sbjct: 4202 WKKDNVLL---ANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHTVSLTV 4256
Score = 56.4 bits (130), Expect = 7e-08
Identities = 46/181 (25%), Positives = 70/181 (38%), Gaps = 11/181 (6%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+ VE C G P P I+W + I + L I D G YTC
Sbjct: 3261 GENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCV 3320
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A+N G+ L VY T + + A T +V+ N+ +C G P P
Sbjct: 3321 ATNPAGEEDRIFNLNVYVTPTIRG-NKDEAEKLMT-----LVDTSINI--ECRATGTPPP 3372
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
+W K+G + S+ I + +++RI+ + DV +Y N G L+
Sbjct: 3373 QINWLKNGLPLPLSSHIRLLAAGQVIRIV---RAQVSDVAVYTCVASNRAGVDNKHYNLQ 3429
Query: 186 V 186
V
Sbjct: 3430 V 3430
Score = 56.4 bits (130), Expect = 7e-08
Identities = 49/174 (28%), Positives = 63/174 (36%), Gaps = 17/174 (9%)
Query: 13 CQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLGK 72
C+ TG P P I W + + G L+I + ED GTY C A N G
Sbjct: 4009 CEATGTPSPFITWQKEGINVNTSGRNHAVLPSGG--LQISRAVREDAGTYMCVAQNPAGT 4066
Query: 73 AKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKD 132
A L V Q+ P + V+ + +T C G P P +W KD
Sbjct: 4067 ALGKIKLNV-----------QVPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKD 4115
Query: 133 GSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
G I S R V L+I V D G Y N G + S +L V
Sbjct: 4116 GRAIVESIRQRVLSSGS----LQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTV 4165
Score = 56.0 bits (129), Expect = 1e-07
Identities = 45/180 (25%), Positives = 72/180 (40%), Gaps = 14/180 (7%)
Query: 8 TVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEAS 67
++ EC+ TG P P I W + + R+ QV+ D YTC AS
Sbjct: 3359 SINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVS--DVAVYTCVAS 3416
Query: 68 NCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWA 127
N G + L V+ + + M T V +G + + C G P+P
Sbjct: 3417 NRAGVDNKHYNLQVFAPPNMDN---SMGTEEIT------VLKGSSTSMACITDGTPAPSM 3467
Query: 128 SWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVI 187
+W +DG + A +TV ++++L+ + ED G Y NE G L+V+
Sbjct: 3468 AWLRDGQPLGLDAHLTVSTHGMVLQLLKAE---TEDSGKYTCIASNEAGEVSKHFILKVL 3524
Score = 55.6 bits (128), Expect = 1e-07
Identities = 48/183 (26%), Positives = 70/183 (38%), Gaps = 16/183 (8%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
VE CQ P P + W + S + + LKI+ +D G YTCEA+N
Sbjct: 2121 VELLCQSDAIPPPTLTWLKDGHPLLKKPGL--SISENRSVLKIEDAQVQDTGRYTCEATN 2178
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
GK + N + ++ + T V EG ++ C G P P
Sbjct: 2179 VAGKTEKNYNVNIWVPPNIGGSDELTQLT---------VIEGNLISLLCESSGIPPPNLI 2229
Query: 129 WDKDGS-IITPS-ARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W K GS ++T S R+ + R L+I D +Y N G A+ L+V
Sbjct: 2230 WKKKGSPVLTDSMGRVRILSGG---RQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQV 2286
Query: 187 ITR 189
R
Sbjct: 2287 YIR 2289
Score = 55.2 bits (127), Expect = 2e-07
Identities = 48/180 (26%), Positives = 66/180 (36%), Gaps = 14/180 (7%)
Query: 7 DTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEA 66
++V C+ +G P P I WF + G L++ Q T ED G YTC
Sbjct: 2402 NSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRIL--SGGRMLRLMQTTMEDAGQYTCVV 2459
Query: 67 SNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPW 126
N G+ + ++ L P T V+E ++VT C V GNP P
Sbjct: 2460 RNAAGEERK-----IFGLSVLVPPHIVGENTLEDVK----VKEKQSVTLTCEVTGNPVPE 2510
Query: 127 ASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
+W KDG P R L+I V + G Y + G S L V
Sbjct: 2511 ITWHKDGQ---PLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNV 2567
Score = 54.4 bits (125), Expect = 3e-07
Identities = 43/169 (25%), Positives = 67/169 (39%), Gaps = 11/169 (6%)
Query: 8 TVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEAS 67
+V C+VTGNP P+I W + +++ D G L+I V G YTC AS
Sbjct: 2496 SVTLTCEVTGNPVPEITWHKDGQPLQE--DEAHHIISGGRFLQITNVQVPHTGRYTCLAS 2553
Query: 68 NCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWA 127
+ G + L V+ + ++ G P T N + C P
Sbjct: 2554 SPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILN------SPTSLVCEAYSYPPATI 2607
Query: 128 SWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG 176
+W KDG+ + + I + ++IL E ++ G Y NE G
Sbjct: 2608 TWFKDGTPLESNRNIRILPGGRTLQILNAQE---DNAGRYSCVATNEAG 2653
Score = 54.4 bits (125), Expect = 3e-07
Identities = 43/173 (24%), Positives = 72/173 (41%), Gaps = 10/173 (5%)
Query: 7 DTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEA 66
+T+ EC+ P + W+ + ++ + + T L+IK+ D G YTC A
Sbjct: 2690 NTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHT--LQIKEAQISDTGRYTCVA 2747
Query: 67 SNCLGKAKSNACL---VVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
SN G+ + + + V ++L G M T V+ ++ C P
Sbjct: 2748 SNIAGEDELDFDVNIQVPPSFQKLWEIG-NMLDTGRNGEAKDVIINNP-ISLYCETNAAP 2805
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG 176
P +W KDG +T S ++ + R+L+I +ED G Y NE G
Sbjct: 2806 PPTLTWYKDGHPLTSSDKVLILPGG---RVLQIPRAKVEDAGRYTCVAVNEAG 2855
Score = 53.6 bits (123), Expect = 5e-07
Identities = 40/178 (22%), Positives = 66/178 (37%), Gaps = 15/178 (8%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
V EC+ G P P + W + ++ G L + D G YTC A N
Sbjct: 2029 VRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRI-LALTSAQISDTGRYTCVAVN 2087
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G+ + + L VY + P N V + V C P P +
Sbjct: 2088 AAGEKQRDIDLRVY-----------VPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLT 2136
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KDG + +++ E +L+I++ ++D G Y N G+ E + + +
Sbjct: 2137 WLKDGHPLLKKPGLSISENRS---VLKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNI 2191
Score = 52.8 bits (121), Expect = 9e-07
Identities = 46/179 (25%), Positives = 67/179 (37%), Gaps = 18/179 (10%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
V EC+ P P I W E ++ A G L+I D YTC ASN
Sbjct: 3639 VTLECKSDAVPPPVITWLRNGERLQ--ATPRVRILSGGRYLQINNADLGDTANYTCVASN 3696
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
GK L V + P P + V+ ++ +C +G P+P +
Sbjct: 3697 IAGKTTREFILTV-----------NVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRIT 3745
Query: 129 WDKDGSIITPS-ARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KDG+++ + AR ++ E L I + D G Y N G L+V
Sbjct: 3746 WRKDGAVLAGNHARYSILEN----GFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQV 3800
Score = 52.0 bits (119), Expect = 2e-06
Identities = 47/178 (26%), Positives = 68/178 (38%), Gaps = 12/178 (6%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
+ C+ P P + W+ + +D G L+I + ED G YTC A N
Sbjct: 2795 ISLYCETNAAPPPTLTWYKDGHPLTS-SDKVLILPGGRV-LQIPRAKVEDAGRYTCVAVN 2852
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G+ + Y R L P + A + P V ++ +C G+P+P S
Sbjct: 2853 EAGEDS-----LQYDVRVLVPPIIKGANS--DLPEEVTVLVNKSALIECLSSGSPAPRNS 2905
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KDG + RIL+I I D+G Y EN G A+ L V
Sbjct: 2906 WQKDGQPLLEDDHHKFLSNG---RILQILNTQITDIGRYVCVAENTAGSAKKYFNLNV 2960
Score = 50.8 bits (116), Expect = 4e-06
Identities = 45/179 (25%), Positives = 68/179 (37%), Gaps = 17/179 (9%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
V+ EC+ GNP P I W+ ++ ++ + + I+ D G Y C A N
Sbjct: 1938 VQLECKAAGNPVPVITWYKDNRLLSGSTSM--TFLNRGQIIDIESAQISDAGIYKCVAIN 1995
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G + L V+ +S +A V V +C +G P+P +
Sbjct: 1996 SAGATELFYSLQVHVAPSISGSNNMVA-----------VVVNNPVRLECEARGIPAPSLT 2044
Query: 129 WDKDGSIITP-SARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KDGS ++ S + V RIL + I D G Y N G + L V
Sbjct: 2045 WLKDGSPVSSFSNGLQVLSGG---RILALTSAQISDTGRYTCVAVNAAGEKQRDIDLRV 2100
Score = 48.8 bits (111), Expect = 1e-05
Identities = 40/171 (23%), Positives = 68/171 (39%), Gaps = 18/171 (10%)
Query: 8 TVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEAS 67
++ EC+ GNP P + W ++ A+ + G +L+I D G Y C A+
Sbjct: 1658 SLTLECKAAGNPSPILTWLKDGVPVK--ANDNIRIEAGGKKLEIMSAQEIDRGQYICVAT 1715
Query: 68 NCLGKAKSNACLVVYHTRRLSSPGRQMA--PTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
+ G+ + + Y L P + +++ N ++E C V G+P P
Sbjct: 1716 SVAGEKE-----IKYEVDVLVPPAIEGGDETSYFIVMVNNLLE------LDCHVTGSPPP 1764
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG 176
W KDG +I + R L I + + + G+YR N G
Sbjct: 1765 TIMWLKDGQLIDERDGFKILLNG---RKLVIAQAQVSNTGLYRCMAANTAG 1812
Score = 47.6 bits (108), Expect = 3e-05
Identities = 43/174 (24%), Positives = 57/174 (32%), Gaps = 16/174 (9%)
Query: 13 CQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLGK 72
C +G P P I W + D G + Q+ G YTC A N G
Sbjct: 3918 CTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQLN--HAGRYTCVARNAAGS 3975
Query: 73 AKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKD 132
A + L V+ P P V + C G PSP+ +W K+
Sbjct: 3976 AHRHVTLHVHEP-----------PVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKE 4024
Query: 133 GSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
G + S R L+I ED G Y +N G A +L V
Sbjct: 4025 GINVNTSGR---NHAVLPSGGLQISRAVREDAGTYMCVAQNPAGTALGKIKLNV 4075
Score = 47.2 bits (107), Expect = 4e-05
Identities = 48/180 (26%), Positives = 67/180 (37%), Gaps = 24/180 (13%)
Query: 12 ECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLG 71
EC G P P I W V+ S ++G ++ VT D G Y C A+N G
Sbjct: 3733 ECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLHIQSAHVT--DTGRYLCMATNAAG 3790
Query: 72 KAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDK 131
+ L V H +PG P N V T C G P P +W K
Sbjct: 3791 TDRRRIDLQV-HVPPSIAPG----------PTNMTVIVNVQTTLACEATGIPKPSINWRK 3839
Query: 132 DGSIITPSARITVKEKEEIMRILE-----IDEVSIEDVGIYRITVENELGRAEASARLEV 186
+G + + V + + R+L I S++D Y TV N G + + L V
Sbjct: 3840 NGHL------LNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGDDKRTVDLTV 3893
Score = 46.8 bits (106), Expect = 6e-05
Identities = 38/171 (22%), Positives = 63/171 (36%), Gaps = 14/171 (8%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G + C G P P + W + + D + L++ + ED G YTC
Sbjct: 3450 GSSTSMACITDGTPAPSMAWLRDGQPLG--LDAHLTVSTHGMVLQLLKAETEDSGKYTCI 3507
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
ASN G+ + L V ++ + +V +T C G P+P
Sbjct: 3508 ASNEAGEVSKHFILKVLEPPHINGSEEHEE-------ISVIVNNPLELT--CIASGIPAP 3558
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG 176
+W KDG + + ++ E++R I +ED G Y + G
Sbjct: 3559 KMTWMKDGRPLPQTDQVQTLGGGEVLR---ISTAQVEDTGRYTCLASSPAG 3606
Score = 42.3 bits (95), Expect = 0.001
Identities = 41/176 (23%), Positives = 60/176 (34%), Gaps = 18/176 (10%)
Query: 13 CQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLGK 72
C+ TG P P I W ++ + S + L I + +D TY C +N G
Sbjct: 3825 CEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGD 3884
Query: 73 AKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKD 132
K L V Q+ P+ P + +V + C G P P W K+
Sbjct: 3885 DKRTVDLTV-----------QVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKN 3933
Query: 133 GSIITPSARITVKEKEEIMR--ILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
G + P + I+ +EI + G Y N G A L V
Sbjct: 3934 GIRLLPRG-----DGYRILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHV 3984
Score = 41.9 bits (94), Expect = 0.002
Identities = 38/167 (22%), Positives = 59/167 (35%), Gaps = 8/167 (4%)
Query: 13 CQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLGK 72
C+ P I WF + + G L+I ++ G Y+C A+N G+
Sbjct: 2597 CEAYSYPPATITWFKDGTPLESNRNIRIL--PGGRTLQILNAQEDNAGRYSCVATNEAGE 2654
Query: 73 AKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKD 132
+ + VY + + G P P ++ +T +C PS SW KD
Sbjct: 2655 MIKHYEVKVY-IPPIINKGDLWGPGLS--PKEVKIKVNNTLTLECEAYAIPSASLSWYKD 2711
Query: 133 GSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAE 179
G + + + L+I E I D G Y N G E
Sbjct: 2712 GQPLKSDDHVNIAANG---HTLQIKEAQISDTGRYTCVASNIAGEDE 2755
Score = 40.7 bits (91), Expect = 0.004
Identities = 36/169 (21%), Positives = 61/169 (36%), Gaps = 14/169 (8%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
+E C +G P P + W + ++ G L+I ED G YTC AS+
Sbjct: 3546 LELTCIASGIPAPKMTWMKDGRPLPQTDQVQTL--GGGEVLRISTAQVEDTGRYTCLASS 3603
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G + V+ ++ P + V VT +C P P +
Sbjct: 3604 PAGDDDKEYLVRVHVPPNIAGTDE---------PRDITVLRNRQVTLECKSDAVPPPVIT 3654
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGR 177
W ++G + + R+ + R L+I+ + D Y N G+
Sbjct: 3655 WLRNGERLQATPRVRILSGG---RYLQINNADLGDTANYTCVASNIAGK 3700
Score = 40.3 bits (90), Expect = 0.005
Identities = 34/139 (24%), Positives = 52/139 (37%), Gaps = 15/139 (10%)
Query: 49 LKIKQVTAEDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVE 108
L++K V D G Y C S+ G + ++ L V Q P P N+
Sbjct: 576 LELKSVKFNDAGEYHCMVSSEGGSSAASVFLTV-----------QEPPKVTVMPKNQSFT 624
Query: 109 EGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYR 168
G V+ C+ G P P +W + I S R + + I + +D GIY
Sbjct: 625 GGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGTLF----IKNAAPKDAGIYG 680
Query: 169 ITVENELGRAEASARLEVI 187
N G + ++ L I
Sbjct: 681 CLASNSAGTDKQNSTLRYI 699
Score = 39.9 bits (89), Expect = 0.007
Identities = 43/175 (24%), Positives = 63/175 (36%), Gaps = 15/175 (8%)
Query: 12 ECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLG 71
EC +G+P P W + + + D +G L+I D G Y C A N G
Sbjct: 2893 ECLSSGSPAPRNSWQKDGQPLLE-DDHHKFLSNGRI-LQILNTQITDIGRYVCVAENTAG 2950
Query: 72 KAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDK 131
AK L V+ + P + N V ++ C V G P P SW K
Sbjct: 2951 SAKKYFNLNVHVPPSVIGPKSE----------NLTVVVNNFISLTCEVSGFPPPDLSWLK 3000
Query: 132 DGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
+ I + + R L+I + D G Y N+ G ++ L V
Sbjct: 3001 NEQPIKLNTNTLIVPGG---RTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTV 3052
Score = 39.1 bits (87), Expect = 0.012
Identities = 35/144 (24%), Positives = 53/144 (36%), Gaps = 13/144 (9%)
Query: 43 DDGTARLKIKQVTAEDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYP 102
+ + L I +VT DEG Y C A + G ++ V S P P P
Sbjct: 478 ESASVNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDV------SEP-----PPVIQVP 526
Query: 103 FNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIE 162
N V GE C + +W ++ + + ++ + LE+ V
Sbjct: 527 NNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLS--LELKSVKFN 584
Query: 163 DVGIYRITVENELGRAEASARLEV 186
D G Y V +E G + AS L V
Sbjct: 585 DAGEYHCMVSSEGGSSAASVFLTV 608
>AL121996-1|CAI17844.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-118G19 on chromosome 1q25.1-31.1. ).
Length = 5635
Score = 75.4 bits (177), Expect = 1e-13
Identities = 55/183 (30%), Positives = 78/183 (42%), Gaps = 10/183 (5%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G V C+ +GNP P + W E+I + S+ DG+ L + E+ G Y C
Sbjct: 994 EGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGS--LYVVSPGGEESGEYVC 1051
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
A+N G AK L VY R+ R ++ P V GE VT C VK P
Sbjct: 1052 TATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQD---KPVEISVLAGEEVTLPCEVKSLPP 1108
Query: 125 PWASWDKDGSIITP-SARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
P +W K+ +I+P S R T ++I E D G+Y N G + +
Sbjct: 1109 PIITWAKETQLISPFSPRHTFLPSGS----MKITETRTSDSGMYLCVATNIAGNVTQAVK 1164
Query: 184 LEV 186
L V
Sbjct: 1165 LNV 1167
Score = 74.5 bits (175), Expect = 3e-13
Identities = 48/178 (26%), Positives = 75/178 (42%), Gaps = 13/178 (7%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
V +C G P+P I W + + G L+I + ED G YTC A+N
Sbjct: 1844 VALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATN 1902
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G+ + + L V+ L G+ + N+ V V +C GNP P +
Sbjct: 1903 AAGETQQHIQLHVHEPPSLEDAGKML---------NETVLVSNPVQLECKAAGNPVPVIT 1953
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KD +++ S +T + + I++I+ I D GIY+ N G E L+V
Sbjct: 1954 WYKDNRLLSGSTSMTFLNRGQ---IIDIESAQISDAGIYKCVAINSAGATELFYSLQV 2008
Score = 70.9 bits (166), Expect = 3e-12
Identities = 60/180 (33%), Positives = 80/180 (44%), Gaps = 20/180 (11%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+ + C+ TG P P + W +I A F+S +G + L I++V+ ED GTY C
Sbjct: 4274 GEQLRLSCKATGIPLPKLTWTFNNNIIP--AHFDSV--NGHSELVIERVSKEDSGTYVCT 4329
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFY-TYPFNKVVEEGENVTFKCAVKGNPS 124
A N +G K A VY + P P F YP N + G N C VKG+P+
Sbjct: 4330 AENSVGFVK--AIGFVY----VKEP-----PVFKGDYPSNWIEPLGGNAILNCEVKGDPT 4378
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
P W++ G I S RI ++ L I ED G Y NE G E S L
Sbjct: 4379 PTIQWNRKGVDIEISHRI----RQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSL 4434
Score = 68.5 bits (160), Expect = 2e-11
Identities = 47/179 (26%), Positives = 78/179 (43%), Gaps = 13/179 (7%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
++ EC+ G P P I W+ + I + ++ Y D L I + D TYTC +N
Sbjct: 1565 IKLECETRGLPMPAITWYKDGQPIMSSS--QALYIDKGQYLHIPRAQVSDSATYTCHVAN 1622
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G A+ + + VY + +A P NK V ++T +C GNPSP +
Sbjct: 1623 VAGTAEKSFHVDVYVPPMIEG---NLAT-----PLNKQVVIAHSLTLECKAAGNPSPILT 1674
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVI 187
W KDG + + I ++ + + I+ E+ D G Y + G E ++V+
Sbjct: 1675 WLKDGVPVKANDNIRIEAGGKKLEIMSAQEI---DRGQYICVATSVAGEKEIKYEVDVL 1730
Score = 67.7 bits (158), Expect = 3e-11
Identities = 43/182 (23%), Positives = 79/182 (43%), Gaps = 11/182 (6%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G+ + C+ +G P P++ W + + G +L+I D Y+C
Sbjct: 2210 EGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSC 2269
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
ASN G AK L VY +++ G ++P +V G++++ +C V+G P
Sbjct: 2270 VASNVAGTAKKEYNLQVYIRPTITNSG--------SHPTEIIVTRGKSISLECEVQGIPP 2321
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
P +W KDG + + + + ++ IL++ + + D G Y N G + L
Sbjct: 2322 PTVTWMKDGHPLIKAKGVEILDEG---HILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDL 2378
Query: 185 EV 186
V
Sbjct: 2379 SV 2380
Score = 66.5 bits (155), Expect = 7e-11
Identities = 53/174 (30%), Positives = 73/174 (41%), Gaps = 16/174 (9%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFE-SSYDD-GTARLKIKQVTAEDEGTYT 63
G V C V G P+P I+W + F SS T L I + A D+GTY
Sbjct: 807 GSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYI 866
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCA-VKGN 122
CEA N GK +S + V +AP P V EG+ +T C + GN
Sbjct: 867 CEAENQFGKIQSETTVTVTGL---------VAPLIGISPSVANVIEGQQLTLPCTLLAGN 917
Query: 123 PSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG 176
P P W K+ +++ + ITV+ L I+ V ++D G Y N G
Sbjct: 918 PIPERRWIKNSAMLLQNPYITVRSDGS----LHIERVQLQDGGEYTCVASNVAG 967
Score = 66.5 bits (155), Expect = 7e-11
Identities = 50/178 (28%), Positives = 71/178 (39%), Gaps = 13/178 (7%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
V ECQV G P PDI WF + + D D L +K D+G Y C SN
Sbjct: 1471 VALECQVKGTPFPDIHWFKDGKPL-FLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSN 1529
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
GK + L +Y + T + N +++ +C +G P P +
Sbjct: 1530 AAGKQAKDIKLTIYIPPSIKGGN---VTTDISVLINSLIK------LECETRGLPMPAIT 1580
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KDG I S++ +K + L I + D Y V N G AE S ++V
Sbjct: 1581 WYKDGQPIMSSSQALYIDKGQ---YLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDV 1635
Score = 65.7 bits (153), Expect = 1e-10
Identities = 46/178 (25%), Positives = 74/178 (41%), Gaps = 12/178 (6%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
+ C+V+G P PD+ W + I+ + + G L+I + D G YTC A N
Sbjct: 2982 ISLTCEVSGFPPPDLSWLKNEQPIK--LNTNTLIVPGGRTLQIIRAKVSDGGEYTCIAIN 3039
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G++K L VY + + V EG +V+ +C P P +
Sbjct: 3040 QAGESKKKFSLTVYVPPSIKDHDSESLSVVN-------VREGTSVSLECESNAVPPPVIT 3092
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W K+G +IT S + + + +L I + + D G Y N GR + + L V
Sbjct: 3093 WYKNGRMITESTHVEILADGQ---MLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNV 3147
Score = 65.3 bits (152), Expect = 2e-10
Identities = 52/182 (28%), Positives = 75/182 (41%), Gaps = 14/182 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
GD EC+ +G P P ++WF +R D LKI++ D G YTC
Sbjct: 716 GDITVMECKTSGIPPPQVKWFKGDLELRPSTFL--IIDPLLGLLKIQETQDLDAGDYTCV 773
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A N G+A L V SP P F P + +E G NVT C V+G P P
Sbjct: 774 AINEAGRATGKITLDV------GSP-----PVFIQEPADVSMEIGSNVTLPCYVQGYPEP 822
Query: 126 WASWDKDGSIITPSARITVKEKEEIMR-ILEIDEVSIEDVGIYRITVENELGRAEASARL 184
W + ++ S +V ++ L I + D G Y EN+ G+ ++ +
Sbjct: 823 TIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTV 882
Query: 185 EV 186
V
Sbjct: 883 TV 884
Score = 64.9 bits (151), Expect = 2e-10
Identities = 57/198 (28%), Positives = 82/198 (41%), Gaps = 19/198 (9%)
Query: 5 DGDTVEFECQV-TGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYT 63
+G + C + GNP P+ RW + ++ + + DG+ L I++V +D G YT
Sbjct: 903 EGQQLTLPCTLLAGNPIPERRWIKNSAMLLQ-NPYITVRSDGS--LHIERVQLQDGGEYT 959
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
C ASN G +VV H G+Q+ T EG VT C GNP
Sbjct: 960 CVASNVAGTNNKTTSVVV-HVLPTIQHGQQILSTI----------EGIPVTLPCKASGNP 1008
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
P W K G +I+ S + K L + E+ G Y T N G A+ +
Sbjct: 1009 KPSVIWSKKGELISTS---SAKFSAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKVQ 1065
Query: 184 LEVITRSGKFYGGLRAYS 201
L V R + +G R S
Sbjct: 1066 LTVYVRP-RVFGDQRGLS 1082
Score = 63.7 bits (148), Expect = 5e-10
Identities = 53/181 (29%), Positives = 70/181 (38%), Gaps = 17/181 (9%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G V C TG P P I W I + + DGT L IK +D G Y C
Sbjct: 626 GSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMT-SDGT--LFIKNAAPKDAGIYGCL 682
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
ASN G K N+ L R + AP +V G+ +C G P P
Sbjct: 683 ASNSAGTDKQNSTL-----RYIE------APKLMVVQSELLVALGDITVMECKTSGIPPP 731
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
W K + PS + + + ++ +L+I E D G Y NE GRA L+
Sbjct: 732 QVKWFKGDLELRPSTFLII---DPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLD 788
Query: 186 V 186
V
Sbjct: 789 V 789
Score = 63.7 bits (148), Expect = 5e-10
Identities = 47/178 (26%), Positives = 78/178 (43%), Gaps = 14/178 (7%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
+E +C VTG+P P I W ++I + F+ + +L I Q + G Y C A+N
Sbjct: 1752 LELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNG--RKLVIAQAQVSNTGLYRCMAAN 1809
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G K + V+ + S G +VV + + V +C G P+P +
Sbjct: 1810 TAGDHKKEFEVTVHVPPTIKSSGLS----------ERVVVKYKPVALQCIANGIPNPSIT 1859
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KD + +A+ +K + R+L+I + +ED G Y N G + +L V
Sbjct: 1860 WLKDDQPVN-TAQGNLKIQSS-GRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHV 1915
Score = 63.3 bits (147), Expect = 6e-10
Identities = 47/182 (25%), Positives = 73/182 (40%), Gaps = 13/182 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G ++ EC+V G P P + W + E D+G L++K + D G Y C
Sbjct: 2307 GKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEI-LDEGHI-LQLKNIHVSDTGRYVCV 2364
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A N G L V+ + R P N V E +V+ C G P P
Sbjct: 2365 AVNVAGMTDKKYDLSVHAPPSIIGNHRS--------PENISVVEKNSVSLTCEASGIPLP 2416
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
+W KDG ++ S + + ++R++ + ++ED G Y V N G L
Sbjct: 2417 SITWFKDGWPVSLSNSVRILSGGRMLRLM---QTTMEDAGQYTCVVRNAAGEERKIFGLS 2473
Query: 186 VI 187
V+
Sbjct: 2474 VL 2475
Score = 62.9 bits (146), Expect = 8e-10
Identities = 50/179 (27%), Positives = 71/179 (39%), Gaps = 13/179 (7%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
+EF C G P P I+W H + S +DGT L I VT D G Y C A N
Sbjct: 1284 IEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGTL-LVIASVTPYDNGEYICVAVN 1342
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G + L V H + Q+ N V + C V+G PSP
Sbjct: 1343 EAGTTERKYNLKV-HVPPVIKDKEQVT--------NVSVLLNQLTNLFCEVEGTPSPIIM 1393
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVI 187
W KD +T S+ I +I+++ + ED G Y N G ++ ++V+
Sbjct: 1394 WYKDNVQVTESSTIQTVNNGKILKLF---RATPEDAGRYSCKAINIAGTSQKYFNIDVL 1449
Score = 62.1 bits (144), Expect = 1e-09
Identities = 52/182 (28%), Positives = 71/182 (39%), Gaps = 12/182 (6%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G V+ C G P P I W + + S DGT L I Q T D G YTC
Sbjct: 1185 GQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGT--LSIDQATPSDAGIYTCV 1242
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A+N G ++ L V + + P + T +V + + F C KG P P
Sbjct: 1243 ATNIAGTDETEITLHVQEPPTVED----LEPPYNTTFQERVANQ--RIEFPCPAKGTPKP 1296
Query: 126 WASWDKDGSIIT-PSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
W +G +T I++ E +L I V+ D G Y NE G E L
Sbjct: 1297 TIKWLHNGRELTGREPGISILEDG---TLLVIASVTPYDNGEYICVAVNEAGTTERKYNL 1353
Query: 185 EV 186
+V
Sbjct: 1354 KV 1355
Score = 61.7 bits (143), Expect = 2e-09
Identities = 47/181 (25%), Positives = 68/181 (37%), Gaps = 16/181 (8%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+ V C+V P P I W ++I + + G+ +KI + D G Y C
Sbjct: 1094 GEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGS--MKITETRTSDSGMYLCV 1151
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A+N G L V+ + P P + V+ G+ V C +G P P
Sbjct: 1152 ATNIAGNVTQAVKLNVH-----------VPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLP 1200
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
+W K GS + V + L ID+ + D GIY N G E L
Sbjct: 1201 VITWSKGGSTMLVDGEHHVSNPD---GTLSIDQATPSDAGIYTCVATNIAGTDETEITLH 1257
Query: 186 V 186
V
Sbjct: 1258 V 1258
Score = 61.3 bits (142), Expect = 3e-09
Identities = 50/178 (28%), Positives = 64/178 (35%), Gaps = 10/178 (5%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
V C TG P P I W + I + E G ++L+I + D G YTC ASN
Sbjct: 3169 VTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASN 3228
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
GKA+ Y+ + P P + V GENV C G P+P
Sbjct: 3229 MEGKAQK------YYFLSIQVPPSVAGAEI---PSDVSVLLGENVELVCNANGIPTPLIQ 3279
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KDG I ++ L I D G Y N G + L V
Sbjct: 3280 WLKDGKPIASGETERIRVSAN-GSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNV 3336
Score = 60.1 bits (139), Expect = 6e-09
Identities = 48/168 (28%), Positives = 73/168 (43%), Gaps = 18/168 (10%)
Query: 13 CQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLGK 72
C G P P I W ++ + ++ G L ++ V ED G YTC A+N G+
Sbjct: 4190 CVADGIPTPAINWKKDNVLLANLLGKYTAEPYG--ELILENVVLEDSGFYTCVANNAAGE 4247
Query: 73 AKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKD 132
L V+ + PTF P + + +GE + C G P P +W +
Sbjct: 4248 DTHTVSLTVH-----------VLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFN 4296
Query: 133 GSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEA 180
+II P+ +V E++ I+ VS ED G Y T EN +G +A
Sbjct: 4297 NNII-PAHFDSVNGHSELV----IERVSKEDSGTYVCTAENSVGFVKA 4339
Score = 58.0 bits (134), Expect = 2e-08
Identities = 44/175 (25%), Positives = 75/175 (42%), Gaps = 15/175 (8%)
Query: 13 CQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLGK 72
C+V G P P I W+ + + + ++ ++G LK+ + T ED G Y+C+A N G
Sbjct: 1382 CEVEGTPSPIIMWYKDNVQVTESSTIQT-VNNGKI-LKLFRATPEDAGRYSCKAINIAGT 1439
Query: 73 AKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKD 132
++ Y + P + F P V +V +C VKG P P W KD
Sbjct: 1440 SQK------YFNIDVLVPPTIIGTNF---PNEVSVVLNRDVALECQVKGTPFPDIHWFKD 1490
Query: 133 GS-IITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
G + + + ++ + +L + D G Y+ TV N G+ +L +
Sbjct: 1491 GKPLFLGDPNVELLDRGQ---VLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTI 1542
Score = 57.6 bits (133), Expect = 3e-08
Identities = 49/176 (27%), Positives = 69/176 (39%), Gaps = 15/176 (8%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G +V EC+ P P I W+ +I + E D L IK+ D G Y C
Sbjct: 3073 EGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADG--QMLHIKKAEVSDTGQYVC 3130
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGEN-VTFKCAVKGNP 123
A N G+ N L VY + P R++ +VE N VT C G P
Sbjct: 3131 RAINVAGRDDKNFHLNVYVPPSIEGPEREV-----------IVETISNPVTLTCDATGIP 3179
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAE 179
P +W K+ I S + V+ + L+I D G Y N G+A+
Sbjct: 3180 PPTIAWLKNHKRIENSDSLEVRILSGGSK-LQIARSQHSDSGNYTCIASNMEGKAQ 3234
Score = 57.2 bits (132), Expect = 4e-08
Identities = 54/200 (27%), Positives = 74/200 (37%), Gaps = 29/200 (14%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSY---DDGTARLKIKQVTAEDEGTY 62
G C+V G+P P I+W R D E S+ G L I ED G Y
Sbjct: 4364 GGNAILNCEVKGDPTPTIQWN------RKGVDIEISHRIRQLGNGSLAIYGTVNEDAGDY 4417
Query: 63 TCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGN 122
TC A+N G + + L L SP P P V+ G + C G
Sbjct: 4418 TCVATNEAGVVERSMSLT------LQSP-----PIITLEPVETVINAGGKIILNCQATGE 4466
Query: 123 PSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASA 182
P P +W + G I+ R+ V L I + ED + N +G
Sbjct: 4467 PQPTITWSRQGHSISWDDRVNVLSNNS----LYIADAQKEDTSEFECVARNLMG--SVLV 4520
Query: 183 RLEVITRSGKFYGGLRAYSA 202
R+ VI + +GG +SA
Sbjct: 4521 RVPVIV---QVHGGFSQWSA 4537
Score = 56.8 bits (131), Expect = 6e-08
Identities = 48/178 (26%), Positives = 69/178 (38%), Gaps = 17/178 (9%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
+ C+ G P PDI W I + + G+ L+I V D G YTC A+N
Sbjct: 4096 ITLSCEADGLPPPDITWHKDGRAIVESIR-QRVLSSGS--LQIAFVQPGDAGHYTCMAAN 4152
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G + ++ L V+ R+ S YT V E C G P+P +
Sbjct: 4153 VAGSSSTSTKLTVHVPPRIRS-----TEGHYT------VNENSQAILPCVADGIPTPAIN 4201
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KD ++ A + K E L ++ V +ED G Y N G + L V
Sbjct: 4202 WKKDNVLL---ANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHTVSLTV 4256
Score = 56.4 bits (130), Expect = 7e-08
Identities = 46/181 (25%), Positives = 70/181 (38%), Gaps = 11/181 (6%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+ VE C G P P I+W + I + L I D G YTC
Sbjct: 3261 GENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCV 3320
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A+N G+ L VY T + + A T +V+ N+ +C G P P
Sbjct: 3321 ATNPAGEEDRIFNLNVYVTPTIRG-NKDEAEKLMT-----LVDTSINI--ECRATGTPPP 3372
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
+W K+G + S+ I + +++RI+ + DV +Y N G L+
Sbjct: 3373 QINWLKNGLPLPLSSHIRLLAAGQVIRIV---RAQVSDVAVYTCVASNRAGVDNKHYNLQ 3429
Query: 186 V 186
V
Sbjct: 3430 V 3430
Score = 56.4 bits (130), Expect = 7e-08
Identities = 49/174 (28%), Positives = 63/174 (36%), Gaps = 17/174 (9%)
Query: 13 CQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLGK 72
C+ TG P P I W + + G L+I + ED GTY C A N G
Sbjct: 4009 CEATGTPSPFITWQKEGINVNTSGRNHAVLPSGG--LQISRAVREDAGTYMCVAQNPAGT 4066
Query: 73 AKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKD 132
A L V Q+ P + V+ + +T C G P P +W KD
Sbjct: 4067 ALGKIKLNV-----------QVPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKD 4115
Query: 133 GSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
G I S R V L+I V D G Y N G + S +L V
Sbjct: 4116 GRAIVESIRQRVLSSGS----LQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTV 4165
Score = 56.0 bits (129), Expect = 1e-07
Identities = 45/180 (25%), Positives = 72/180 (40%), Gaps = 14/180 (7%)
Query: 8 TVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEAS 67
++ EC+ TG P P I W + + R+ QV+ D YTC AS
Sbjct: 3359 SINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVS--DVAVYTCVAS 3416
Query: 68 NCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWA 127
N G + L V+ + + M T V +G + + C G P+P
Sbjct: 3417 NRAGVDNKHYNLQVFAPPNMDN---SMGTEEIT------VLKGSSTSMACITDGTPAPSM 3467
Query: 128 SWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVI 187
+W +DG + A +TV ++++L+ + ED G Y NE G L+V+
Sbjct: 3468 AWLRDGQPLGLDAHLTVSTHGMVLQLLKAE---TEDSGKYTCIASNEAGEVSKHFILKVL 3524
Score = 55.6 bits (128), Expect = 1e-07
Identities = 48/183 (26%), Positives = 70/183 (38%), Gaps = 16/183 (8%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
VE CQ P P + W + S + + LKI+ +D G YTCEA+N
Sbjct: 2121 VELLCQSDAIPPPTLTWLKDGHPLLKKPGL--SISENRSVLKIEDAQVQDTGRYTCEATN 2178
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
GK + N + ++ + T V EG ++ C G P P
Sbjct: 2179 VAGKTEKNYNVNIWVPPNIGGSDELTQLT---------VIEGNLISLLCESSGIPPPNLI 2229
Query: 129 WDKDGS-IITPS-ARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W K GS ++T S R+ + R L+I D +Y N G A+ L+V
Sbjct: 2230 WKKKGSPVLTDSMGRVRILSGG---RQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQV 2286
Query: 187 ITR 189
R
Sbjct: 2287 YIR 2289
Score = 55.2 bits (127), Expect = 2e-07
Identities = 48/180 (26%), Positives = 66/180 (36%), Gaps = 14/180 (7%)
Query: 7 DTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEA 66
++V C+ +G P P I WF + G L++ Q T ED G YTC
Sbjct: 2402 NSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRIL--SGGRMLRLMQTTMEDAGQYTCVV 2459
Query: 67 SNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPW 126
N G+ + ++ L P T V+E ++VT C V GNP P
Sbjct: 2460 RNAAGEERK-----IFGLSVLVPPHIVGENTLEDVK----VKEKQSVTLTCEVTGNPVPE 2510
Query: 127 ASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
+W KDG P R L+I V + G Y + G S L V
Sbjct: 2511 ITWHKDGQ---PLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNV 2567
Score = 54.4 bits (125), Expect = 3e-07
Identities = 43/169 (25%), Positives = 67/169 (39%), Gaps = 11/169 (6%)
Query: 8 TVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEAS 67
+V C+VTGNP P+I W + +++ D G L+I V G YTC AS
Sbjct: 2496 SVTLTCEVTGNPVPEITWHKDGQPLQE--DEAHHIISGGRFLQITNVQVPHTGRYTCLAS 2553
Query: 68 NCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWA 127
+ G + L V+ + ++ G P T N + C P
Sbjct: 2554 SPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILN------SPTSLVCEAYSYPPATI 2607
Query: 128 SWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG 176
+W KDG+ + + I + ++IL E ++ G Y NE G
Sbjct: 2608 TWFKDGTPLESNRNIRILPGGRTLQILNAQE---DNAGRYSCVATNEAG 2653
Score = 54.4 bits (125), Expect = 3e-07
Identities = 43/173 (24%), Positives = 72/173 (41%), Gaps = 10/173 (5%)
Query: 7 DTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEA 66
+T+ EC+ P + W+ + ++ + + T L+IK+ D G YTC A
Sbjct: 2690 NTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHT--LQIKEAQISDTGRYTCVA 2747
Query: 67 SNCLGKAKSNACL---VVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
SN G+ + + + V ++L G M T V+ ++ C P
Sbjct: 2748 SNIAGEDELDFDVNIQVPPSFQKLWEIG-NMLDTGRNGEAKDVIINNP-ISLYCETNAAP 2805
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG 176
P +W KDG +T S ++ + R+L+I +ED G Y NE G
Sbjct: 2806 PPTLTWYKDGHPLTSSDKVLILPGG---RVLQIPRAKVEDAGRYTCVAVNEAG 2855
Score = 53.6 bits (123), Expect = 5e-07
Identities = 40/178 (22%), Positives = 66/178 (37%), Gaps = 15/178 (8%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
V EC+ G P P + W + ++ G L + D G YTC A N
Sbjct: 2029 VRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRI-LALTSAQISDTGRYTCVAVN 2087
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G+ + + L VY + P N V + V C P P +
Sbjct: 2088 AAGEKQRDIDLRVY-----------VPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLT 2136
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KDG + +++ E +L+I++ ++D G Y N G+ E + + +
Sbjct: 2137 WLKDGHPLLKKPGLSISENRS---VLKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNI 2191
Score = 52.8 bits (121), Expect = 9e-07
Identities = 46/179 (25%), Positives = 67/179 (37%), Gaps = 18/179 (10%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
V EC+ P P I W E ++ A G L+I D YTC ASN
Sbjct: 3639 VTLECKSDAVPPPVITWLRNGERLQ--ATPRVRILSGGRYLQINNADLGDTANYTCVASN 3696
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
GK L V + P P + V+ ++ +C +G P+P +
Sbjct: 3697 IAGKTTREFILTV-----------NVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRIT 3745
Query: 129 WDKDGSIITPS-ARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KDG+++ + AR ++ E L I + D G Y N G L+V
Sbjct: 3746 WRKDGAVLAGNHARYSILEN----GFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQV 3800
Score = 52.0 bits (119), Expect = 2e-06
Identities = 47/178 (26%), Positives = 68/178 (38%), Gaps = 12/178 (6%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
+ C+ P P + W+ + +D G L+I + ED G YTC A N
Sbjct: 2795 ISLYCETNAAPPPTLTWYKDGHPLTS-SDKVLILPGGRV-LQIPRAKVEDAGRYTCVAVN 2852
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G+ + Y R L P + A + P V ++ +C G+P+P S
Sbjct: 2853 EAGEDS-----LQYDVRVLVPPIIKGANS--DLPEEVTVLVNKSALIECLSSGSPAPRNS 2905
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KDG + RIL+I I D+G Y EN G A+ L V
Sbjct: 2906 WQKDGQPLLEDDHHKFLSNG---RILQILNTQITDIGRYVCVAENTAGSAKKYFNLNV 2960
Score = 50.8 bits (116), Expect = 4e-06
Identities = 45/179 (25%), Positives = 68/179 (37%), Gaps = 17/179 (9%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
V+ EC+ GNP P I W+ ++ ++ + + I+ D G Y C A N
Sbjct: 1938 VQLECKAAGNPVPVITWYKDNRLLSGSTSM--TFLNRGQIIDIESAQISDAGIYKCVAIN 1995
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G + L V+ +S +A V V +C +G P+P +
Sbjct: 1996 SAGATELFYSLQVHVAPSISGSNNMVA-----------VVVNNPVRLECEARGIPAPSLT 2044
Query: 129 WDKDGSIITP-SARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KDGS ++ S + V RIL + I D G Y N G + L V
Sbjct: 2045 WLKDGSPVSSFSNGLQVLSGG---RILALTSAQISDTGRYTCVAVNAAGEKQRDIDLRV 2100
Score = 48.8 bits (111), Expect = 1e-05
Identities = 40/171 (23%), Positives = 68/171 (39%), Gaps = 18/171 (10%)
Query: 8 TVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEAS 67
++ EC+ GNP P + W ++ A+ + G +L+I D G Y C A+
Sbjct: 1658 SLTLECKAAGNPSPILTWLKDGVPVK--ANDNIRIEAGGKKLEIMSAQEIDRGQYICVAT 1715
Query: 68 NCLGKAKSNACLVVYHTRRLSSPGRQMA--PTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
+ G+ + + Y L P + +++ N ++E C V G+P P
Sbjct: 1716 SVAGEKE-----IKYEVDVLVPPAIEGGDETSYFIVMVNNLLE------LDCHVTGSPPP 1764
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG 176
W KDG +I + R L I + + + G+YR N G
Sbjct: 1765 TIMWLKDGQLIDERDGFKILLNG---RKLVIAQAQVSNTGLYRCMAANTAG 1812
Score = 47.6 bits (108), Expect = 3e-05
Identities = 43/174 (24%), Positives = 57/174 (32%), Gaps = 16/174 (9%)
Query: 13 CQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLGK 72
C +G P P I W + D G + Q+ G YTC A N G
Sbjct: 3918 CTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQLN--HAGRYTCVARNAAGS 3975
Query: 73 AKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKD 132
A + L V+ P P V + C G PSP+ +W K+
Sbjct: 3976 AHRHVTLHVHEP-----------PVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKE 4024
Query: 133 GSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
G + S R L+I ED G Y +N G A +L V
Sbjct: 4025 GINVNTSGR---NHAVLPSGGLQISRAVREDAGTYMCVAQNPAGTALGKIKLNV 4075
Score = 47.2 bits (107), Expect = 4e-05
Identities = 48/180 (26%), Positives = 67/180 (37%), Gaps = 24/180 (13%)
Query: 12 ECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLG 71
EC G P P I W V+ S ++G ++ VT D G Y C A+N G
Sbjct: 3733 ECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLHIQSAHVT--DTGRYLCMATNAAG 3790
Query: 72 KAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDK 131
+ L V H +PG P N V T C G P P +W K
Sbjct: 3791 TDRRRIDLQV-HVPPSIAPG----------PTNMTVIVNVQTTLACEATGIPKPSINWRK 3839
Query: 132 DGSIITPSARITVKEKEEIMRILE-----IDEVSIEDVGIYRITVENELGRAEASARLEV 186
+G + + V + + R+L I S++D Y TV N G + + L V
Sbjct: 3840 NGHL------LNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGDDKRTVDLTV 3893
Score = 46.8 bits (106), Expect = 6e-05
Identities = 38/171 (22%), Positives = 63/171 (36%), Gaps = 14/171 (8%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G + C G P P + W + + D + L++ + ED G YTC
Sbjct: 3450 GSSTSMACITDGTPAPSMAWLRDGQPLG--LDAHLTVSTHGMVLQLLKAETEDSGKYTCI 3507
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
ASN G+ + L V ++ + +V +T C G P+P
Sbjct: 3508 ASNEAGEVSKHFILKVLEPPHINGSEEHEE-------ISVIVNNPLELT--CIASGIPAP 3558
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG 176
+W KDG + + ++ E++R I +ED G Y + G
Sbjct: 3559 KMTWMKDGRPLPQTDQVQTLGGGEVLR---ISTAQVEDTGRYTCLASSPAG 3606
Score = 42.3 bits (95), Expect = 0.001
Identities = 41/176 (23%), Positives = 60/176 (34%), Gaps = 18/176 (10%)
Query: 13 CQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLGK 72
C+ TG P P I W ++ + S + L I + +D TY C +N G
Sbjct: 3825 CEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGD 3884
Query: 73 AKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKD 132
K L V Q+ P+ P + +V + C G P P W K+
Sbjct: 3885 DKRTVDLTV-----------QVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKN 3933
Query: 133 GSIITPSARITVKEKEEIMR--ILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
G + P + I+ +EI + G Y N G A L V
Sbjct: 3934 GIRLLPRG-----DGYRILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHV 3984
Score = 41.9 bits (94), Expect = 0.002
Identities = 38/167 (22%), Positives = 59/167 (35%), Gaps = 8/167 (4%)
Query: 13 CQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLGK 72
C+ P I WF + + G L+I ++ G Y+C A+N G+
Sbjct: 2597 CEAYSYPPATITWFKDGTPLESNRNIRIL--PGGRTLQILNAQEDNAGRYSCVATNEAGE 2654
Query: 73 AKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKD 132
+ + VY + + G P P ++ +T +C PS SW KD
Sbjct: 2655 MIKHYEVKVY-IPPIINKGDLWGPGLS--PKEVKIKVNNTLTLECEAYAIPSASLSWYKD 2711
Query: 133 GSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAE 179
G + + + L+I E I D G Y N G E
Sbjct: 2712 GQPLKSDDHVNIAANG---HTLQIKEAQISDTGRYTCVASNIAGEDE 2755
Score = 40.7 bits (91), Expect = 0.004
Identities = 36/169 (21%), Positives = 61/169 (36%), Gaps = 14/169 (8%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
+E C +G P P + W + ++ G L+I ED G YTC AS+
Sbjct: 3546 LELTCIASGIPAPKMTWMKDGRPLPQTDQVQTL--GGGEVLRISTAQVEDTGRYTCLASS 3603
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G + V+ ++ P + V VT +C P P +
Sbjct: 3604 PAGDDDKEYLVRVHVPPNIAGTDE---------PRDITVLRNRQVTLECKSDAVPPPVIT 3654
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGR 177
W ++G + + R+ + R L+I+ + D Y N G+
Sbjct: 3655 WLRNGERLQATPRVRILSGG---RYLQINNADLGDTANYTCVASNIAGK 3700
Score = 40.3 bits (90), Expect = 0.005
Identities = 34/139 (24%), Positives = 52/139 (37%), Gaps = 15/139 (10%)
Query: 49 LKIKQVTAEDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVE 108
L++K V D G Y C S+ G + ++ L V Q P P N+
Sbjct: 576 LELKSVKFNDAGEYHCMVSSEGGSSAASVFLTV-----------QEPPKVTVMPKNQSFT 624
Query: 109 EGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYR 168
G V+ C+ G P P +W + I S R + + I + +D GIY
Sbjct: 625 GGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGTLF----IKNAAPKDAGIYG 680
Query: 169 ITVENELGRAEASARLEVI 187
N G + ++ L I
Sbjct: 681 CLASNSAGTDKQNSTLRYI 699
Score = 39.9 bits (89), Expect = 0.007
Identities = 43/175 (24%), Positives = 63/175 (36%), Gaps = 15/175 (8%)
Query: 12 ECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLG 71
EC +G+P P W + + + D +G L+I D G Y C A N G
Sbjct: 2893 ECLSSGSPAPRNSWQKDGQPLLE-DDHHKFLSNGRI-LQILNTQITDIGRYVCVAENTAG 2950
Query: 72 KAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDK 131
AK L V+ + P + N V ++ C V G P P SW K
Sbjct: 2951 SAKKYFNLNVHVPPSVIGPKSE----------NLTVVVNNFISLTCEVSGFPPPDLSWLK 3000
Query: 132 DGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
+ I + + R L+I + D G Y N+ G ++ L V
Sbjct: 3001 NEQPIKLNTNTLIVPGG---RTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTV 3052
Score = 39.1 bits (87), Expect = 0.012
Identities = 35/144 (24%), Positives = 53/144 (36%), Gaps = 13/144 (9%)
Query: 43 DDGTARLKIKQVTAEDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYP 102
+ + L I +VT DEG Y C A + G ++ V S P P P
Sbjct: 478 ESASVNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDV------SEP-----PPVIQVP 526
Query: 103 FNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIE 162
N V GE C + +W ++ + + ++ + LE+ V
Sbjct: 527 NNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLS--LELKSVKFN 584
Query: 163 DVGIYRITVENELGRAEASARLEV 186
D G Y V +E G + AS L V
Sbjct: 585 DAGEYHCMVSSEGGSSAASVFLTV 608
>AL118512-1|CAI17864.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-248A21 on chromosome 1q31.1-31.3. ).
Length = 5635
Score = 75.4 bits (177), Expect = 1e-13
Identities = 55/183 (30%), Positives = 78/183 (42%), Gaps = 10/183 (5%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G V C+ +GNP P + W E+I + S+ DG+ L + E+ G Y C
Sbjct: 994 EGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGS--LYVVSPGGEESGEYVC 1051
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
A+N G AK L VY R+ R ++ P V GE VT C VK P
Sbjct: 1052 TATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQD---KPVEISVLAGEEVTLPCEVKSLPP 1108
Query: 125 PWASWDKDGSIITP-SARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
P +W K+ +I+P S R T ++I E D G+Y N G + +
Sbjct: 1109 PIITWAKETQLISPFSPRHTFLPSGS----MKITETRTSDSGMYLCVATNIAGNVTQAVK 1164
Query: 184 LEV 186
L V
Sbjct: 1165 LNV 1167
Score = 74.5 bits (175), Expect = 3e-13
Identities = 48/178 (26%), Positives = 75/178 (42%), Gaps = 13/178 (7%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
V +C G P+P I W + + G L+I + ED G YTC A+N
Sbjct: 1844 VALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATN 1902
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G+ + + L V+ L G+ + N+ V V +C GNP P +
Sbjct: 1903 AAGETQQHIQLHVHEPPSLEDAGKML---------NETVLVSNPVQLECKAAGNPVPVIT 1953
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KD +++ S +T + + I++I+ I D GIY+ N G E L+V
Sbjct: 1954 WYKDNRLLSGSTSMTFLNRGQ---IIDIESAQISDAGIYKCVAINSAGATELFYSLQV 2008
Score = 70.9 bits (166), Expect = 3e-12
Identities = 60/180 (33%), Positives = 80/180 (44%), Gaps = 20/180 (11%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+ + C+ TG P P + W +I A F+S +G + L I++V+ ED GTY C
Sbjct: 4274 GEQLRLSCKATGIPLPKLTWTFNNNIIP--AHFDSV--NGHSELVIERVSKEDSGTYVCT 4329
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFY-TYPFNKVVEEGENVTFKCAVKGNPS 124
A N +G K A VY + P P F YP N + G N C VKG+P+
Sbjct: 4330 AENSVGFVK--AIGFVY----VKEP-----PVFKGDYPSNWIEPLGGNAILNCEVKGDPT 4378
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
P W++ G I S RI ++ L I ED G Y NE G E S L
Sbjct: 4379 PTIQWNRKGVDIEISHRI----RQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSL 4434
Score = 68.5 bits (160), Expect = 2e-11
Identities = 47/179 (26%), Positives = 78/179 (43%), Gaps = 13/179 (7%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
++ EC+ G P P I W+ + I + ++ Y D L I + D TYTC +N
Sbjct: 1565 IKLECETRGLPMPAITWYKDGQPIMSSS--QALYIDKGQYLHIPRAQVSDSATYTCHVAN 1622
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G A+ + + VY + +A P NK V ++T +C GNPSP +
Sbjct: 1623 VAGTAEKSFHVDVYVPPMIEG---NLAT-----PLNKQVVIAHSLTLECKAAGNPSPILT 1674
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVI 187
W KDG + + I ++ + + I+ E+ D G Y + G E ++V+
Sbjct: 1675 WLKDGVPVKANDNIRIEAGGKKLEIMSAQEI---DRGQYICVATSVAGEKEIKYEVDVL 1730
Score = 67.7 bits (158), Expect = 3e-11
Identities = 43/182 (23%), Positives = 79/182 (43%), Gaps = 11/182 (6%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G+ + C+ +G P P++ W + + G +L+I D Y+C
Sbjct: 2210 EGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSC 2269
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
ASN G AK L VY +++ G ++P +V G++++ +C V+G P
Sbjct: 2270 VASNVAGTAKKEYNLQVYIRPTITNSG--------SHPTEIIVTRGKSISLECEVQGIPP 2321
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
P +W KDG + + + + ++ IL++ + + D G Y N G + L
Sbjct: 2322 PTVTWMKDGHPLIKAKGVEILDEG---HILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDL 2378
Query: 185 EV 186
V
Sbjct: 2379 SV 2380
Score = 66.5 bits (155), Expect = 7e-11
Identities = 53/174 (30%), Positives = 73/174 (41%), Gaps = 16/174 (9%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFE-SSYDD-GTARLKIKQVTAEDEGTYT 63
G V C V G P+P I+W + F SS T L I + A D+GTY
Sbjct: 807 GSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYI 866
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCA-VKGN 122
CEA N GK +S + V +AP P V EG+ +T C + GN
Sbjct: 867 CEAENQFGKIQSETTVTVTGL---------VAPLIGISPSVANVIEGQQLTLPCTLLAGN 917
Query: 123 PSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG 176
P P W K+ +++ + ITV+ L I+ V ++D G Y N G
Sbjct: 918 PIPERRWIKNSAMLLQNPYITVRSDGS----LHIERVQLQDGGEYTCVASNVAG 967
Score = 66.5 bits (155), Expect = 7e-11
Identities = 50/178 (28%), Positives = 71/178 (39%), Gaps = 13/178 (7%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
V ECQV G P PDI WF + + D D L +K D+G Y C SN
Sbjct: 1471 VALECQVKGTPFPDIHWFKDGKPL-FLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSN 1529
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
GK + L +Y + T + N +++ +C +G P P +
Sbjct: 1530 AAGKQAKDIKLTIYIPPSIKGGN---VTTDISVLINSLIK------LECETRGLPMPAIT 1580
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KDG I S++ +K + L I + D Y V N G AE S ++V
Sbjct: 1581 WYKDGQPIMSSSQALYIDKGQ---YLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDV 1635
Score = 65.7 bits (153), Expect = 1e-10
Identities = 46/178 (25%), Positives = 74/178 (41%), Gaps = 12/178 (6%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
+ C+V+G P PD+ W + I+ + + G L+I + D G YTC A N
Sbjct: 2982 ISLTCEVSGFPPPDLSWLKNEQPIK--LNTNTLIVPGGRTLQIIRAKVSDGGEYTCIAIN 3039
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G++K L VY + + V EG +V+ +C P P +
Sbjct: 3040 QAGESKKKFSLTVYVPPSIKDHDSESLSVVN-------VREGTSVSLECESNAVPPPVIT 3092
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W K+G +IT S + + + +L I + + D G Y N GR + + L V
Sbjct: 3093 WYKNGRMITESTHVEILADGQ---MLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNV 3147
Score = 65.3 bits (152), Expect = 2e-10
Identities = 52/182 (28%), Positives = 75/182 (41%), Gaps = 14/182 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
GD EC+ +G P P ++WF +R D LKI++ D G YTC
Sbjct: 716 GDITVMECKTSGIPPPQVKWFKGDLELRPSTFL--IIDPLLGLLKIQETQDLDAGDYTCV 773
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A N G+A L V SP P F P + +E G NVT C V+G P P
Sbjct: 774 AINEAGRATGKITLDV------GSP-----PVFIQEPADVSMEIGSNVTLPCYVQGYPEP 822
Query: 126 WASWDKDGSIITPSARITVKEKEEIMR-ILEIDEVSIEDVGIYRITVENELGRAEASARL 184
W + ++ S +V ++ L I + D G Y EN+ G+ ++ +
Sbjct: 823 TIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTV 882
Query: 185 EV 186
V
Sbjct: 883 TV 884
Score = 64.9 bits (151), Expect = 2e-10
Identities = 57/198 (28%), Positives = 82/198 (41%), Gaps = 19/198 (9%)
Query: 5 DGDTVEFECQV-TGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYT 63
+G + C + GNP P+ RW + ++ + + DG+ L I++V +D G YT
Sbjct: 903 EGQQLTLPCTLLAGNPIPERRWIKNSAMLLQ-NPYITVRSDGS--LHIERVQLQDGGEYT 959
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
C ASN G +VV H G+Q+ T EG VT C GNP
Sbjct: 960 CVASNVAGTNNKTTSVVV-HVLPTIQHGQQILSTI----------EGIPVTLPCKASGNP 1008
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
P W K G +I+ S + K L + E+ G Y T N G A+ +
Sbjct: 1009 KPSVIWSKKGELISTS---SAKFSAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKVQ 1065
Query: 184 LEVITRSGKFYGGLRAYS 201
L V R + +G R S
Sbjct: 1066 LTVYVRP-RVFGDQRGLS 1082
Score = 63.7 bits (148), Expect = 5e-10
Identities = 53/181 (29%), Positives = 70/181 (38%), Gaps = 17/181 (9%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G V C TG P P I W I + + DGT L IK +D G Y C
Sbjct: 626 GSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMT-SDGT--LFIKNAAPKDAGIYGCL 682
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
ASN G K N+ L R + AP +V G+ +C G P P
Sbjct: 683 ASNSAGTDKQNSTL-----RYIE------APKLMVVQSELLVALGDITVMECKTSGIPPP 731
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
W K + PS + + + ++ +L+I E D G Y NE GRA L+
Sbjct: 732 QVKWFKGDLELRPSTFLII---DPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLD 788
Query: 186 V 186
V
Sbjct: 789 V 789
Score = 63.7 bits (148), Expect = 5e-10
Identities = 47/178 (26%), Positives = 78/178 (43%), Gaps = 14/178 (7%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
+E +C VTG+P P I W ++I + F+ + +L I Q + G Y C A+N
Sbjct: 1752 LELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNG--RKLVIAQAQVSNTGLYRCMAAN 1809
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G K + V+ + S G +VV + + V +C G P+P +
Sbjct: 1810 TAGDHKKEFEVTVHVPPTIKSSGLS----------ERVVVKYKPVALQCIANGIPNPSIT 1859
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KD + +A+ +K + R+L+I + +ED G Y N G + +L V
Sbjct: 1860 WLKDDQPVN-TAQGNLKIQSS-GRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHV 1915
Score = 63.3 bits (147), Expect = 6e-10
Identities = 47/182 (25%), Positives = 73/182 (40%), Gaps = 13/182 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G ++ EC+V G P P + W + E D+G L++K + D G Y C
Sbjct: 2307 GKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEI-LDEGHI-LQLKNIHVSDTGRYVCV 2364
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A N G L V+ + R P N V E +V+ C G P P
Sbjct: 2365 AVNVAGMTDKKYDLSVHAPPSIIGNHRS--------PENISVVEKNSVSLTCEASGIPLP 2416
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
+W KDG ++ S + + ++R++ + ++ED G Y V N G L
Sbjct: 2417 SITWFKDGWPVSLSNSVRILSGGRMLRLM---QTTMEDAGQYTCVVRNAAGEERKIFGLS 2473
Query: 186 VI 187
V+
Sbjct: 2474 VL 2475
Score = 62.9 bits (146), Expect = 8e-10
Identities = 50/179 (27%), Positives = 71/179 (39%), Gaps = 13/179 (7%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
+EF C G P P I+W H + S +DGT L I VT D G Y C A N
Sbjct: 1284 IEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGTL-LVIASVTPYDNGEYICVAVN 1342
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G + L V H + Q+ N V + C V+G PSP
Sbjct: 1343 EAGTTERKYNLKV-HVPPVIKDKEQVT--------NVSVLLNQLTNLFCEVEGTPSPIIM 1393
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVI 187
W KD +T S+ I +I+++ + ED G Y N G ++ ++V+
Sbjct: 1394 WYKDNVQVTESSTIQTVNNGKILKLF---RATPEDAGRYSCKAINIAGTSQKYFNIDVL 1449
Score = 62.1 bits (144), Expect = 1e-09
Identities = 52/182 (28%), Positives = 71/182 (39%), Gaps = 12/182 (6%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G V+ C G P P I W + + S DGT L I Q T D G YTC
Sbjct: 1185 GQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGT--LSIDQATPSDAGIYTCV 1242
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A+N G ++ L V + + P + T +V + + F C KG P P
Sbjct: 1243 ATNIAGTDETEITLHVQEPPTVED----LEPPYNTTFQERVANQ--RIEFPCPAKGTPKP 1296
Query: 126 WASWDKDGSIIT-PSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
W +G +T I++ E +L I V+ D G Y NE G E L
Sbjct: 1297 TIKWLHNGRELTGREPGISILEDG---TLLVIASVTPYDNGEYICVAVNEAGTTERKYNL 1353
Query: 185 EV 186
+V
Sbjct: 1354 KV 1355
Score = 61.7 bits (143), Expect = 2e-09
Identities = 47/181 (25%), Positives = 68/181 (37%), Gaps = 16/181 (8%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+ V C+V P P I W ++I + + G+ +KI + D G Y C
Sbjct: 1094 GEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGS--MKITETRTSDSGMYLCV 1151
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A+N G L V+ + P P + V+ G+ V C +G P P
Sbjct: 1152 ATNIAGNVTQAVKLNVH-----------VPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLP 1200
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
+W K GS + V + L ID+ + D GIY N G E L
Sbjct: 1201 VITWSKGGSTMLVDGEHHVSNPD---GTLSIDQATPSDAGIYTCVATNIAGTDETEITLH 1257
Query: 186 V 186
V
Sbjct: 1258 V 1258
Score = 61.3 bits (142), Expect = 3e-09
Identities = 50/178 (28%), Positives = 64/178 (35%), Gaps = 10/178 (5%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
V C TG P P I W + I + E G ++L+I + D G YTC ASN
Sbjct: 3169 VTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASN 3228
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
GKA+ Y+ + P P + V GENV C G P+P
Sbjct: 3229 MEGKAQK------YYFLSIQVPPSVAGAEI---PSDVSVLLGENVELVCNANGIPTPLIQ 3279
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KDG I ++ L I D G Y N G + L V
Sbjct: 3280 WLKDGKPIASGETERIRVSAN-GSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNV 3336
Score = 60.1 bits (139), Expect = 6e-09
Identities = 48/168 (28%), Positives = 73/168 (43%), Gaps = 18/168 (10%)
Query: 13 CQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLGK 72
C G P P I W ++ + ++ G L ++ V ED G YTC A+N G+
Sbjct: 4190 CVADGIPTPAINWKKDNVLLANLLGKYTAEPYG--ELILENVVLEDSGFYTCVANNAAGE 4247
Query: 73 AKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKD 132
L V+ + PTF P + + +GE + C G P P +W +
Sbjct: 4248 DTHTVSLTVH-----------VLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFN 4296
Query: 133 GSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEA 180
+II P+ +V E++ I+ VS ED G Y T EN +G +A
Sbjct: 4297 NNII-PAHFDSVNGHSELV----IERVSKEDSGTYVCTAENSVGFVKA 4339
Score = 58.0 bits (134), Expect = 2e-08
Identities = 44/175 (25%), Positives = 75/175 (42%), Gaps = 15/175 (8%)
Query: 13 CQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLGK 72
C+V G P P I W+ + + + ++ ++G LK+ + T ED G Y+C+A N G
Sbjct: 1382 CEVEGTPSPIIMWYKDNVQVTESSTIQT-VNNGKI-LKLFRATPEDAGRYSCKAINIAGT 1439
Query: 73 AKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKD 132
++ Y + P + F P V +V +C VKG P P W KD
Sbjct: 1440 SQK------YFNIDVLVPPTIIGTNF---PNEVSVVLNRDVALECQVKGTPFPDIHWFKD 1490
Query: 133 GS-IITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
G + + + ++ + +L + D G Y+ TV N G+ +L +
Sbjct: 1491 GKPLFLGDPNVELLDRGQ---VLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTI 1542
Score = 57.6 bits (133), Expect = 3e-08
Identities = 49/176 (27%), Positives = 69/176 (39%), Gaps = 15/176 (8%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G +V EC+ P P I W+ +I + E D L IK+ D G Y C
Sbjct: 3073 EGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADG--QMLHIKKAEVSDTGQYVC 3130
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGEN-VTFKCAVKGNP 123
A N G+ N L VY + P R++ +VE N VT C G P
Sbjct: 3131 RAINVAGRDDKNFHLNVYVPPSIEGPEREV-----------IVETISNPVTLTCDATGIP 3179
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAE 179
P +W K+ I S + V+ + L+I D G Y N G+A+
Sbjct: 3180 PPTIAWLKNHKRIENSDSLEVRILSGGSK-LQIARSQHSDSGNYTCIASNMEGKAQ 3234
Score = 57.2 bits (132), Expect = 4e-08
Identities = 54/200 (27%), Positives = 74/200 (37%), Gaps = 29/200 (14%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSY---DDGTARLKIKQVTAEDEGTY 62
G C+V G+P P I+W R D E S+ G L I ED G Y
Sbjct: 4364 GGNAILNCEVKGDPTPTIQWN------RKGVDIEISHRIRQLGNGSLAIYGTVNEDAGDY 4417
Query: 63 TCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGN 122
TC A+N G + + L L SP P P V+ G + C G
Sbjct: 4418 TCVATNEAGVVERSMSLT------LQSP-----PIITLEPVETVINAGGKIILNCQATGE 4466
Query: 123 PSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASA 182
P P +W + G I+ R+ V L I + ED + N +G
Sbjct: 4467 PQPTITWSRQGHSISWDDRVNVLSNNS----LYIADAQKEDTSEFECVARNLMG--SVLV 4520
Query: 183 RLEVITRSGKFYGGLRAYSA 202
R+ VI + +GG +SA
Sbjct: 4521 RVPVIV---QVHGGFSQWSA 4537
Score = 56.8 bits (131), Expect = 6e-08
Identities = 48/178 (26%), Positives = 69/178 (38%), Gaps = 17/178 (9%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
+ C+ G P PDI W I + + G+ L+I V D G YTC A+N
Sbjct: 4096 ITLSCEADGLPPPDITWHKDGRAIVESIR-QRVLSSGS--LQIAFVQPGDAGHYTCMAAN 4152
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G + ++ L V+ R+ S YT V E C G P+P +
Sbjct: 4153 VAGSSSTSTKLTVHVPPRIRS-----TEGHYT------VNENSQAILPCVADGIPTPAIN 4201
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KD ++ A + K E L ++ V +ED G Y N G + L V
Sbjct: 4202 WKKDNVLL---ANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHTVSLTV 4256
Score = 56.4 bits (130), Expect = 7e-08
Identities = 46/181 (25%), Positives = 70/181 (38%), Gaps = 11/181 (6%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+ VE C G P P I+W + I + L I D G YTC
Sbjct: 3261 GENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCV 3320
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A+N G+ L VY T + + A T +V+ N+ +C G P P
Sbjct: 3321 ATNPAGEEDRIFNLNVYVTPTIRG-NKDEAEKLMT-----LVDTSINI--ECRATGTPPP 3372
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
+W K+G + S+ I + +++RI+ + DV +Y N G L+
Sbjct: 3373 QINWLKNGLPLPLSSHIRLLAAGQVIRIV---RAQVSDVAVYTCVASNRAGVDNKHYNLQ 3429
Query: 186 V 186
V
Sbjct: 3430 V 3430
Score = 56.4 bits (130), Expect = 7e-08
Identities = 49/174 (28%), Positives = 63/174 (36%), Gaps = 17/174 (9%)
Query: 13 CQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLGK 72
C+ TG P P I W + + G L+I + ED GTY C A N G
Sbjct: 4009 CEATGTPSPFITWQKEGINVNTSGRNHAVLPSGG--LQISRAVREDAGTYMCVAQNPAGT 4066
Query: 73 AKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKD 132
A L V Q+ P + V+ + +T C G P P +W KD
Sbjct: 4067 ALGKIKLNV-----------QVPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKD 4115
Query: 133 GSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
G I S R V L+I V D G Y N G + S +L V
Sbjct: 4116 GRAIVESIRQRVLSSGS----LQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTV 4165
Score = 56.0 bits (129), Expect = 1e-07
Identities = 45/180 (25%), Positives = 72/180 (40%), Gaps = 14/180 (7%)
Query: 8 TVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEAS 67
++ EC+ TG P P I W + + R+ QV+ D YTC AS
Sbjct: 3359 SINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVS--DVAVYTCVAS 3416
Query: 68 NCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWA 127
N G + L V+ + + M T V +G + + C G P+P
Sbjct: 3417 NRAGVDNKHYNLQVFAPPNMDN---SMGTEEIT------VLKGSSTSMACITDGTPAPSM 3467
Query: 128 SWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVI 187
+W +DG + A +TV ++++L+ + ED G Y NE G L+V+
Sbjct: 3468 AWLRDGQPLGLDAHLTVSTHGMVLQLLKAE---TEDSGKYTCIASNEAGEVSKHFILKVL 3524
Score = 55.6 bits (128), Expect = 1e-07
Identities = 48/183 (26%), Positives = 70/183 (38%), Gaps = 16/183 (8%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
VE CQ P P + W + S + + LKI+ +D G YTCEA+N
Sbjct: 2121 VELLCQSDAIPPPTLTWLKDGHPLLKKPGL--SISENRSVLKIEDAQVQDTGRYTCEATN 2178
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
GK + N + ++ + T V EG ++ C G P P
Sbjct: 2179 VAGKTEKNYNVNIWVPPNIGGSDELTQLT---------VIEGNLISLLCESSGIPPPNLI 2229
Query: 129 WDKDGS-IITPS-ARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W K GS ++T S R+ + R L+I D +Y N G A+ L+V
Sbjct: 2230 WKKKGSPVLTDSMGRVRILSGG---RQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQV 2286
Query: 187 ITR 189
R
Sbjct: 2287 YIR 2289
Score = 55.2 bits (127), Expect = 2e-07
Identities = 48/180 (26%), Positives = 66/180 (36%), Gaps = 14/180 (7%)
Query: 7 DTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEA 66
++V C+ +G P P I WF + G L++ Q T ED G YTC
Sbjct: 2402 NSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRIL--SGGRMLRLMQTTMEDAGQYTCVV 2459
Query: 67 SNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPW 126
N G+ + ++ L P T V+E ++VT C V GNP P
Sbjct: 2460 RNAAGEERK-----IFGLSVLVPPHIVGENTLEDVK----VKEKQSVTLTCEVTGNPVPE 2510
Query: 127 ASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
+W KDG P R L+I V + G Y + G S L V
Sbjct: 2511 ITWHKDGQ---PLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNV 2567
Score = 54.4 bits (125), Expect = 3e-07
Identities = 43/169 (25%), Positives = 67/169 (39%), Gaps = 11/169 (6%)
Query: 8 TVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEAS 67
+V C+VTGNP P+I W + +++ D G L+I V G YTC AS
Sbjct: 2496 SVTLTCEVTGNPVPEITWHKDGQPLQE--DEAHHIISGGRFLQITNVQVPHTGRYTCLAS 2553
Query: 68 NCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWA 127
+ G + L V+ + ++ G P T N + C P
Sbjct: 2554 SPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILN------SPTSLVCEAYSYPPATI 2607
Query: 128 SWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG 176
+W KDG+ + + I + ++IL E ++ G Y NE G
Sbjct: 2608 TWFKDGTPLESNRNIRILPGGRTLQILNAQE---DNAGRYSCVATNEAG 2653
Score = 54.4 bits (125), Expect = 3e-07
Identities = 43/173 (24%), Positives = 72/173 (41%), Gaps = 10/173 (5%)
Query: 7 DTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEA 66
+T+ EC+ P + W+ + ++ + + T L+IK+ D G YTC A
Sbjct: 2690 NTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHT--LQIKEAQISDTGRYTCVA 2747
Query: 67 SNCLGKAKSNACL---VVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
SN G+ + + + V ++L G M T V+ ++ C P
Sbjct: 2748 SNIAGEDELDFDVNIQVPPSFQKLWEIG-NMLDTGRNGEAKDVIINNP-ISLYCETNAAP 2805
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG 176
P +W KDG +T S ++ + R+L+I +ED G Y NE G
Sbjct: 2806 PPTLTWYKDGHPLTSSDKVLILPGG---RVLQIPRAKVEDAGRYTCVAVNEAG 2855
Score = 53.6 bits (123), Expect = 5e-07
Identities = 40/178 (22%), Positives = 66/178 (37%), Gaps = 15/178 (8%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
V EC+ G P P + W + ++ G L + D G YTC A N
Sbjct: 2029 VRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRI-LALTSAQISDTGRYTCVAVN 2087
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G+ + + L VY + P N V + V C P P +
Sbjct: 2088 AAGEKQRDIDLRVY-----------VPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLT 2136
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KDG + +++ E +L+I++ ++D G Y N G+ E + + +
Sbjct: 2137 WLKDGHPLLKKPGLSISENRS---VLKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNI 2191
Score = 52.8 bits (121), Expect = 9e-07
Identities = 46/179 (25%), Positives = 67/179 (37%), Gaps = 18/179 (10%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
V EC+ P P I W E ++ A G L+I D YTC ASN
Sbjct: 3639 VTLECKSDAVPPPVITWLRNGERLQ--ATPRVRILSGGRYLQINNADLGDTANYTCVASN 3696
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
GK L V + P P + V+ ++ +C +G P+P +
Sbjct: 3697 IAGKTTREFILTV-----------NVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRIT 3745
Query: 129 WDKDGSIITPS-ARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KDG+++ + AR ++ E L I + D G Y N G L+V
Sbjct: 3746 WRKDGAVLAGNHARYSILEN----GFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQV 3800
Score = 52.0 bits (119), Expect = 2e-06
Identities = 47/178 (26%), Positives = 68/178 (38%), Gaps = 12/178 (6%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
+ C+ P P + W+ + +D G L+I + ED G YTC A N
Sbjct: 2795 ISLYCETNAAPPPTLTWYKDGHPLTS-SDKVLILPGGRV-LQIPRAKVEDAGRYTCVAVN 2852
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G+ + Y R L P + A + P V ++ +C G+P+P S
Sbjct: 2853 EAGEDS-----LQYDVRVLVPPIIKGANS--DLPEEVTVLVNKSALIECLSSGSPAPRNS 2905
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KDG + RIL+I I D+G Y EN G A+ L V
Sbjct: 2906 WQKDGQPLLEDDHHKFLSNG---RILQILNTQITDIGRYVCVAENTAGSAKKYFNLNV 2960
Score = 50.8 bits (116), Expect = 4e-06
Identities = 45/179 (25%), Positives = 68/179 (37%), Gaps = 17/179 (9%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
V+ EC+ GNP P I W+ ++ ++ + + I+ D G Y C A N
Sbjct: 1938 VQLECKAAGNPVPVITWYKDNRLLSGSTSM--TFLNRGQIIDIESAQISDAGIYKCVAIN 1995
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G + L V+ +S +A V V +C +G P+P +
Sbjct: 1996 SAGATELFYSLQVHVAPSISGSNNMVA-----------VVVNNPVRLECEARGIPAPSLT 2044
Query: 129 WDKDGSIITP-SARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KDGS ++ S + V RIL + I D G Y N G + L V
Sbjct: 2045 WLKDGSPVSSFSNGLQVLSGG---RILALTSAQISDTGRYTCVAVNAAGEKQRDIDLRV 2100
Score = 48.8 bits (111), Expect = 1e-05
Identities = 40/171 (23%), Positives = 68/171 (39%), Gaps = 18/171 (10%)
Query: 8 TVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEAS 67
++ EC+ GNP P + W ++ A+ + G +L+I D G Y C A+
Sbjct: 1658 SLTLECKAAGNPSPILTWLKDGVPVK--ANDNIRIEAGGKKLEIMSAQEIDRGQYICVAT 1715
Query: 68 NCLGKAKSNACLVVYHTRRLSSPGRQMA--PTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
+ G+ + + Y L P + +++ N ++E C V G+P P
Sbjct: 1716 SVAGEKE-----IKYEVDVLVPPAIEGGDETSYFIVMVNNLLE------LDCHVTGSPPP 1764
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG 176
W KDG +I + R L I + + + G+YR N G
Sbjct: 1765 TIMWLKDGQLIDERDGFKILLNG---RKLVIAQAQVSNTGLYRCMAANTAG 1812
Score = 47.6 bits (108), Expect = 3e-05
Identities = 43/174 (24%), Positives = 57/174 (32%), Gaps = 16/174 (9%)
Query: 13 CQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLGK 72
C +G P P I W + D G + Q+ G YTC A N G
Sbjct: 3918 CTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQLN--HAGRYTCVARNAAGS 3975
Query: 73 AKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKD 132
A + L V+ P P V + C G PSP+ +W K+
Sbjct: 3976 AHRHVTLHVHEP-----------PVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKE 4024
Query: 133 GSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
G + S R L+I ED G Y +N G A +L V
Sbjct: 4025 GINVNTSGR---NHAVLPSGGLQISRAVREDAGTYMCVAQNPAGTALGKIKLNV 4075
Score = 47.2 bits (107), Expect = 4e-05
Identities = 48/180 (26%), Positives = 67/180 (37%), Gaps = 24/180 (13%)
Query: 12 ECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLG 71
EC G P P I W V+ S ++G ++ VT D G Y C A+N G
Sbjct: 3733 ECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLHIQSAHVT--DTGRYLCMATNAAG 3790
Query: 72 KAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDK 131
+ L V H +PG P N V T C G P P +W K
Sbjct: 3791 TDRRRIDLQV-HVPPSIAPG----------PTNMTVIVNVQTTLACEATGIPKPSINWRK 3839
Query: 132 DGSIITPSARITVKEKEEIMRILE-----IDEVSIEDVGIYRITVENELGRAEASARLEV 186
+G + + V + + R+L I S++D Y TV N G + + L V
Sbjct: 3840 NGHL------LNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGDDKRTVDLTV 3893
Score = 46.8 bits (106), Expect = 6e-05
Identities = 38/171 (22%), Positives = 63/171 (36%), Gaps = 14/171 (8%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G + C G P P + W + + D + L++ + ED G YTC
Sbjct: 3450 GSSTSMACITDGTPAPSMAWLRDGQPLG--LDAHLTVSTHGMVLQLLKAETEDSGKYTCI 3507
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
ASN G+ + L V ++ + +V +T C G P+P
Sbjct: 3508 ASNEAGEVSKHFILKVLEPPHINGSEEHEE-------ISVIVNNPLELT--CIASGIPAP 3558
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG 176
+W KDG + + ++ E++R I +ED G Y + G
Sbjct: 3559 KMTWMKDGRPLPQTDQVQTLGGGEVLR---ISTAQVEDTGRYTCLASSPAG 3606
Score = 42.3 bits (95), Expect = 0.001
Identities = 41/176 (23%), Positives = 60/176 (34%), Gaps = 18/176 (10%)
Query: 13 CQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLGK 72
C+ TG P P I W ++ + S + L I + +D TY C +N G
Sbjct: 3825 CEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGD 3884
Query: 73 AKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKD 132
K L V Q+ P+ P + +V + C G P P W K+
Sbjct: 3885 DKRTVDLTV-----------QVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKN 3933
Query: 133 GSIITPSARITVKEKEEIMR--ILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
G + P + I+ +EI + G Y N G A L V
Sbjct: 3934 GIRLLPRG-----DGYRILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHV 3984
Score = 41.9 bits (94), Expect = 0.002
Identities = 38/167 (22%), Positives = 59/167 (35%), Gaps = 8/167 (4%)
Query: 13 CQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLGK 72
C+ P I WF + + G L+I ++ G Y+C A+N G+
Sbjct: 2597 CEAYSYPPATITWFKDGTPLESNRNIRIL--PGGRTLQILNAQEDNAGRYSCVATNEAGE 2654
Query: 73 AKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKD 132
+ + VY + + G P P ++ +T +C PS SW KD
Sbjct: 2655 MIKHYEVKVY-IPPIINKGDLWGPGLS--PKEVKIKVNNTLTLECEAYAIPSASLSWYKD 2711
Query: 133 GSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAE 179
G + + + L+I E I D G Y N G E
Sbjct: 2712 GQPLKSDDHVNIAANG---HTLQIKEAQISDTGRYTCVASNIAGEDE 2755
Score = 40.7 bits (91), Expect = 0.004
Identities = 36/169 (21%), Positives = 61/169 (36%), Gaps = 14/169 (8%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
+E C +G P P + W + ++ G L+I ED G YTC AS+
Sbjct: 3546 LELTCIASGIPAPKMTWMKDGRPLPQTDQVQTL--GGGEVLRISTAQVEDTGRYTCLASS 3603
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G + V+ ++ P + V VT +C P P +
Sbjct: 3604 PAGDDDKEYLVRVHVPPNIAGTDE---------PRDITVLRNRQVTLECKSDAVPPPVIT 3654
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGR 177
W ++G + + R+ + R L+I+ + D Y N G+
Sbjct: 3655 WLRNGERLQATPRVRILSGG---RYLQINNADLGDTANYTCVASNIAGK 3700
Score = 40.3 bits (90), Expect = 0.005
Identities = 34/139 (24%), Positives = 52/139 (37%), Gaps = 15/139 (10%)
Query: 49 LKIKQVTAEDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVE 108
L++K V D G Y C S+ G + ++ L V Q P P N+
Sbjct: 576 LELKSVKFNDAGEYHCMVSSEGGSSAASVFLTV-----------QEPPKVTVMPKNQSFT 624
Query: 109 EGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYR 168
G V+ C+ G P P +W + I S R + + I + +D GIY
Sbjct: 625 GGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGTLF----IKNAAPKDAGIYG 680
Query: 169 ITVENELGRAEASARLEVI 187
N G + ++ L I
Sbjct: 681 CLASNSAGTDKQNSTLRYI 699
Score = 39.9 bits (89), Expect = 0.007
Identities = 43/175 (24%), Positives = 63/175 (36%), Gaps = 15/175 (8%)
Query: 12 ECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLG 71
EC +G+P P W + + + D +G L+I D G Y C A N G
Sbjct: 2893 ECLSSGSPAPRNSWQKDGQPLLE-DDHHKFLSNGRI-LQILNTQITDIGRYVCVAENTAG 2950
Query: 72 KAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDK 131
AK L V+ + P + N V ++ C V G P P SW K
Sbjct: 2951 SAKKYFNLNVHVPPSVIGPKSE----------NLTVVVNNFISLTCEVSGFPPPDLSWLK 3000
Query: 132 DGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
+ I + + R L+I + D G Y N+ G ++ L V
Sbjct: 3001 NEQPIKLNTNTLIVPGG---RTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTV 3052
Score = 39.1 bits (87), Expect = 0.012
Identities = 35/144 (24%), Positives = 53/144 (36%), Gaps = 13/144 (9%)
Query: 43 DDGTARLKIKQVTAEDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYP 102
+ + L I +VT DEG Y C A + G ++ V S P P P
Sbjct: 478 ESASVNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDV------SEP-----PPVIQVP 526
Query: 103 FNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIE 162
N V GE C + +W ++ + + ++ + LE+ V
Sbjct: 527 NNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLS--LELKSVKFN 584
Query: 163 DVGIYRITVENELGRAEASARLEV 186
D G Y V +E G + AS L V
Sbjct: 585 DAGEYHCMVSSEGGSSAASVFLTV 608
>AK056336-1|BAB71154.1| 512|Homo sapiens protein ( Homo sapiens
cDNA FLJ31774 fis, clone NT2RI2008050, weakly similar to
BASEMENT MEMBRANE-SPECIFIC HEPARAN SULFATE PROTEOGLYCAN
CORE ).
Length = 512
Score = 75.4 bits (177), Expect = 1e-13
Identities = 55/183 (30%), Positives = 78/183 (42%), Gaps = 10/183 (5%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G V C+ +GNP P + W E+I + S+ DG+ L + E+ G Y C
Sbjct: 335 EGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGS--LYVVSPGGEESGEYVC 392
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
A+N G AK L VY R+ R ++ P V GE VT C VK P
Sbjct: 393 TATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQD---KPVEISVLAGEEVTLPCEVKSLPP 449
Query: 125 PWASWDKDGSIITP-SARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
P +W K+ +I+P S R T ++I E D G+Y N G + +
Sbjct: 450 PIITWAKETQLISPFSPRHTFLPSGS----MKITETRTSDSGMYLCVATNIAGNVTQAVK 505
Query: 184 LEV 186
L V
Sbjct: 506 LNV 508
Score = 66.5 bits (155), Expect = 7e-11
Identities = 53/174 (30%), Positives = 73/174 (41%), Gaps = 16/174 (9%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFE-SSYDD-GTARLKIKQVTAEDEGTYT 63
G V C V G P+P I+W + F SS T L I + A D+GTY
Sbjct: 148 GSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYI 207
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCA-VKGN 122
CEA N GK +S + V +AP P V EG+ +T C + GN
Sbjct: 208 CEAENQFGKIQSETTVTVTGL---------VAPLIGISPSVANVIEGQQLTLPCTLLAGN 258
Query: 123 PSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG 176
P P W K+ +++ + ITV+ L I+ V ++D G Y N G
Sbjct: 259 PIPERRWIKNSAMLLQNPYITVRSDGS----LHIERVQLQDGGEYTCVASNVAG 308
Score = 65.3 bits (152), Expect = 2e-10
Identities = 52/182 (28%), Positives = 75/182 (41%), Gaps = 14/182 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
GD EC+ +G P P ++WF +R D LKI++ D G YTC
Sbjct: 57 GDITVMECKTSGIPPPQVKWFKGDLELRPSTFL--IIDPLLGLLKIQETQDLDAGDYTCV 114
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A N G+A L V SP P F P + +E G NVT C V+G P P
Sbjct: 115 AINEAGRATGKITLDV------GSP-----PVFIQEPADVSMEIGSNVTLPCYVQGYPEP 163
Query: 126 WASWDKDGSIITPSARITVKEKEEIMR-ILEIDEVSIEDVGIYRITVENELGRAEASARL 184
W + ++ S +V ++ L I + D G Y EN+ G+ ++ +
Sbjct: 164 TIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTV 223
Query: 185 EV 186
V
Sbjct: 224 TV 225
Score = 64.9 bits (151), Expect = 2e-10
Identities = 57/198 (28%), Positives = 82/198 (41%), Gaps = 19/198 (9%)
Query: 5 DGDTVEFECQV-TGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYT 63
+G + C + GNP P+ RW + ++ + + DG+ L I++V +D G YT
Sbjct: 244 EGQQLTLPCTLLAGNPIPERRWIKNSAMLLQ-NPYITVRSDGS--LHIERVQLQDGGEYT 300
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
C ASN G +VV H G+Q+ T EG VT C GNP
Sbjct: 301 CVASNVAGTNNKTTSVVV-HVLPTIQHGQQILSTI----------EGIPVTLPCKASGNP 349
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
P W K G +I+ S + K L + E+ G Y T N G A+ +
Sbjct: 350 KPSVIWSKKGELISTS---SAKFSAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKVQ 406
Query: 184 LEVITRSGKFYGGLRAYS 201
L V R + +G R S
Sbjct: 407 LTVYVRP-RVFGDQRGLS 423
Score = 53.2 bits (122), Expect = 7e-07
Identities = 43/143 (30%), Positives = 58/143 (40%), Gaps = 16/143 (11%)
Query: 44 DGTARLKIKQVTAEDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPF 103
DGT L IK +D G Y C ASN G K N+ L R + AP
Sbjct: 4 DGT--LFIKNAAPKDAGIYGCLASNSAGTDKQNSTL-----RYIE------APKLMVVQS 50
Query: 104 NKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIED 163
+V G+ +C G P P W K + PS + + + ++ +L+I E D
Sbjct: 51 ELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPSTFLII---DPLLGLLKIQETQDLD 107
Query: 164 VGIYRITVENELGRAEASARLEV 186
G Y NE GRA L+V
Sbjct: 108 AGDYTCVAINEAGRATGKITLDV 130
Score = 36.7 bits (81), Expect = 0.063
Identities = 21/77 (27%), Positives = 32/77 (41%), Gaps = 2/77 (2%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+ V C+V P P I W ++I + + G+ +KI + D G Y C
Sbjct: 435 GEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGS--MKITETRTSDSGMYLCV 492
Query: 66 ASNCLGKAKSNACLVVY 82
A+N G L V+
Sbjct: 493 ATNIAGNVTQAVKLNVH 509
>AB209333-1|BAD92570.1| 1560|Homo sapiens protein tyrosine
phosphatase, receptor type, sigma isoform 3 precursor
variant protein.
Length = 1560
Score = 75.4 bits (177), Expect = 1e-13
Identities = 59/193 (30%), Positives = 80/193 (41%), Gaps = 12/193 (6%)
Query: 2 LSCDGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGT-ARLKIKQV-TAEDE 59
+ G F CQ TG+P P + W + + +D+ A L+I+ + T DE
Sbjct: 69 IGVSGGVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESAGAVLRIQPLRTPRDE 128
Query: 60 GTYTCEASNCLGKAKSNACLVVYHTRRLSS--PGRQMAPTFYTYPFNKVVEEGENVTFKC 117
Y C A N +G+ +A L V +L S P M P KVVE T C
Sbjct: 129 NVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQL------KVVERTRTATMLC 182
Query: 118 AVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG- 176
A GNP P +W KD + PSA + K+ L+I+ D G Y N G
Sbjct: 183 AASGNPDPEITWFKDFLPVDPSAS-NGRIKQLRSGALQIESSEETDQGKYECVATNSAGV 241
Query: 177 RAEASARLEVITR 189
R + A L V R
Sbjct: 242 RYSSPANLYVRVR 254
Score = 68.9 bits (161), Expect = 1e-11
Identities = 49/179 (27%), Positives = 74/179 (41%), Gaps = 14/179 (7%)
Query: 8 TVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEAS 67
T C +GNPDP+I WF + A + L+I+ D+G Y C A+
Sbjct: 177 TATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEETDQGKYECVAT 236
Query: 68 NCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWA 127
N G S+ + RR+ AP F P + + G NV C G+P P+
Sbjct: 237 NSAGVRYSSPANLYVRVRRV-------APRFSILPMSHEIMPGGNVNITCVAVGSPMPYV 289
Query: 128 SWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W + +TP + V +LE+ +V +D Y + LG EA A++ V
Sbjct: 290 KWMQGAEDLTPEDDMPVGR-----NVLELTDV--KDSANYTCVAMSSLGVIEAVAQITV 341
Score = 46.8 bits (106), Expect = 6e-05
Identities = 29/122 (23%), Positives = 51/122 (41%), Gaps = 2/122 (1%)
Query: 96 PTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILE 155
P F P +++ G +F C G+P P +W+K G + T++ E +L
Sbjct: 59 PRFIKEPKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESAGAVLR 118
Query: 156 IDEV-SIEDVGIYRITVENELGRAEASARLEVITRSGKFYGGLRAYSASPRKCLSYRRRP 214
I + + D +Y +N +G A+L V+ R + G P+ + R R
Sbjct: 119 IQPLRTPRDENVYECVAQNSVGEITVHAKLTVL-REDQLPSGFPNIDMGPQLKVVERTRT 177
Query: 215 ST 216
+T
Sbjct: 178 AT 179
Score = 34.3 bits (75), Expect = 0.34
Identities = 21/76 (27%), Positives = 31/76 (40%), Gaps = 6/76 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G V C G+P P ++W AE D D R ++ +D YTC
Sbjct: 272 GGNVNITCVAVGSPMPYVKWMQGAE------DLTPEDDMPVGRNVLELTDVKDSANYTCV 325
Query: 66 ASNCLGKAKSNACLVV 81
A + LG ++ A + V
Sbjct: 326 AMSSLGVIEAVAQITV 341
>U41725-1|AAD09360.1| 1502|Homo sapiens PTPsigma-(brain) protein.
Length = 1502
Score = 74.9 bits (176), Expect = 2e-13
Identities = 59/193 (30%), Positives = 80/193 (41%), Gaps = 12/193 (6%)
Query: 2 LSCDGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGT-ARLKIKQV-TAEDE 59
+ G F CQ TG+P P + W + + +D+ A L+I+ + T DE
Sbjct: 43 IGVSGRVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESAGAVLRIQPLRTPRDE 102
Query: 60 GTYTCEASNCLGKAKSNACLVVYHTRRLSS--PGRQMAPTFYTYPFNKVVEEGENVTFKC 117
Y C A N +G+ +A L V +L S P M P KVVE T C
Sbjct: 103 NVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQL------KVVERTRTATMLC 156
Query: 118 AVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG- 176
A GNP P +W KD + PSA + K+ L+I+ D G Y N G
Sbjct: 157 AASGNPDPEITWFKDFLPVDPSAS-NGRIKQLRSGALQIESSEETDQGKYECVATNSAGV 215
Query: 177 RAEASARLEVITR 189
R + A L V R
Sbjct: 216 RYSSPANLYVRVR 228
Score = 66.9 bits (156), Expect = 5e-11
Identities = 47/179 (26%), Positives = 73/179 (40%), Gaps = 13/179 (7%)
Query: 8 TVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEAS 67
T C +GNPDP+I WF + A + L+I+ D+G Y C A+
Sbjct: 151 TATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEETDQGKYECVAT 210
Query: 68 NCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWA 127
N G S+ + RR+ AP F P + + G NV C G+P P+
Sbjct: 211 NSAGVRYSSPANLYVRVRRV-------APRFSILPMSHEIMPGGNVNITCVAVGSPMPYV 263
Query: 128 SWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W + +TP + V +LE+ +V + + + LG EA A++ V
Sbjct: 264 KWMQGAEDLTPEDDMPVGR-----NVLELTDVK-DSANYHPCVAMSSLGVIEAVAQITV 316
Score = 47.6 bits (108), Expect = 3e-05
Identities = 29/122 (23%), Positives = 51/122 (41%), Gaps = 2/122 (1%)
Query: 96 PTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILE 155
P F P +++ G +F C G+P P +W+K G + T++ E +L
Sbjct: 33 PRFIKEPKDQIGVSGRVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESAGAVLR 92
Query: 156 IDEV-SIEDVGIYRITVENELGRAEASARLEVITRSGKFYGGLRAYSASPRKCLSYRRRP 214
I + + D +Y +N +G A+L V+ R + G P+ + R R
Sbjct: 93 IQPLRTPRDENVYECVAQNSVGEITVHAKLTVL-REDQLPSGFPNIDMGPQLKVVERTRT 151
Query: 215 ST 216
+T
Sbjct: 152 AT 153
>U40317-1|AAC50567.1| 1911|Homo sapiens PTPsigma protein.
Length = 1911
Score = 74.9 bits (176), Expect = 2e-13
Identities = 59/193 (30%), Positives = 80/193 (41%), Gaps = 12/193 (6%)
Query: 2 LSCDGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGT-ARLKIKQV-TAEDE 59
+ G F CQ TG+P P + W + + +D+ A L+I+ + T DE
Sbjct: 43 IGVSGRVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESAGAVLRIQPLRTPRDE 102
Query: 60 GTYTCEASNCLGKAKSNACLVVYHTRRLSS--PGRQMAPTFYTYPFNKVVEEGENVTFKC 117
Y C A N +G+ +A L V +L S P M P KVVE T C
Sbjct: 103 NVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQL------KVVERTRTATMLC 156
Query: 118 AVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG- 176
A GNP P +W KD + PSA + K+ L+I+ D G Y N G
Sbjct: 157 AASGNPDPEITWFKDFLPVDPSAS-NGRIKQLRSGALQIESSEETDQGKYECVATNSAGV 215
Query: 177 RAEASARLEVITR 189
R + A L V R
Sbjct: 216 RYSSPANLYVRVR 228
Score = 66.9 bits (156), Expect = 5e-11
Identities = 47/179 (26%), Positives = 73/179 (40%), Gaps = 13/179 (7%)
Query: 8 TVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEAS 67
T C +GNPDP+I WF + A + L+I+ D+G Y C A+
Sbjct: 151 TATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEETDQGKYECVAT 210
Query: 68 NCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWA 127
N G S+ + RR+ AP F P + + G NV C G+P P+
Sbjct: 211 NSAGVRYSSPANLYVRVRRV-------APRFSILPMSHEIMPGGNVNITCVAVGSPMPYV 263
Query: 128 SWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W + +TP + V +LE+ +V + + + LG EA A++ V
Sbjct: 264 KWMQGAEDLTPEDDMPVGR-----NVLELTDVK-DSANYHPCVAMSSLGVIEAVAQITV 316
Score = 47.6 bits (108), Expect = 3e-05
Identities = 29/122 (23%), Positives = 51/122 (41%), Gaps = 2/122 (1%)
Query: 96 PTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILE 155
P F P +++ G +F C G+P P +W+K G + T++ E +L
Sbjct: 33 PRFIKEPKDQIGVSGRVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESAGAVLR 92
Query: 156 IDEV-SIEDVGIYRITVENELGRAEASARLEVITRSGKFYGGLRAYSASPRKCLSYRRRP 214
I + + D +Y +N +G A+L V+ R + G P+ + R R
Sbjct: 93 IQPLRTPRDENVYECVAQNSVGEITVHAKLTVL-REDQLPSGFPNIDMGPQLKVVERTRT 151
Query: 215 ST 216
+T
Sbjct: 152 AT 153
>BC130619-1|AAI30620.1| 1100|Homo sapiens CNTN5 protein protein.
Length = 1100
Score = 74.9 bits (176), Expect = 2e-13
Identities = 55/188 (29%), Positives = 80/188 (42%), Gaps = 20/188 (10%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G TV+ EC GNP P I W I A S A L+I V +D G Y C
Sbjct: 315 GTTVKMECFALGNPVPTITWMKVNGYIPSKARLRKSQ----AVLEIPNVQLDDAGIYECR 370
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A N GK L VY P + + ++ G + ++C G P P
Sbjct: 371 AENSRGKNSFRGQLQVY-----------TYPHWVEKLNDTQLDSGSPLRWECKATGKPRP 419
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
W K+G ++P +R+ E + +L I V+ D G+Y+ EN+ G ASA L+
Sbjct: 420 TYRWLKNGVPLSPQSRV-----EMVNGVLMIHNVNQSDAGMYQCLAENKYGAIYASAELK 474
Query: 186 VITRSGKF 193
++ + F
Sbjct: 475 ILASAPTF 482
Score = 62.5 bits (145), Expect = 1e-09
Identities = 40/143 (27%), Positives = 57/143 (39%), Gaps = 5/143 (3%)
Query: 46 TARLKIKQVTAEDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNK 105
T L I +V D G+Y C N + A+ + R G +PF
Sbjct: 251 TGNLYISKVQTSDVGSYICLVKNTVTNARVLSPPTPLTLRNDGVMGEYEPKIEVHFPFTV 310
Query: 106 VVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVG 165
+G V +C GNP P +W K I AR+ + +LEI V ++D G
Sbjct: 311 TAAKGTTVKMECFALGNPVPTITWMKVNGYIPSKARL-----RKSQAVLEIPNVQLDDAG 365
Query: 166 IYRITVENELGRAEASARLEVIT 188
IY EN G+ +L+V T
Sbjct: 366 IYECRAENSRGKNSFRGQLQVYT 388
Score = 62.5 bits (145), Expect = 1e-09
Identities = 55/183 (30%), Positives = 76/183 (41%), Gaps = 20/183 (10%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G + +EC+ TG P P RW + +S + L I V D G Y C
Sbjct: 404 GSPLRWECKATGKPRPTYRWLKNGVPLSP----QSRVEMVNGVLMIHNVNQSDAGMYQCL 459
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNK--VVEEGENVTFKCAVKGNP 123
A N G ++A L + L+S APTF K +V + + V +C +G+P
Sbjct: 460 AENKYGAIYASAELKI-----LAS-----APTFALNQLKKTIIVTKDQEVVIECKPQGSP 509
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
P SW K + + RI + + +RIL S D G Y EN G AE A
Sbjct: 510 KPTISWKKGDRAVRENKRIAIL-PDGSLRIL---NASKSDEGKYVCRGENVFGSAEIIAS 565
Query: 184 LEV 186
L V
Sbjct: 566 LSV 568
Score = 46.8 bits (106), Expect = 6e-05
Identities = 49/178 (27%), Positives = 70/178 (39%), Gaps = 18/178 (10%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
D V C+V GNP P RW I +D+ S DGT + A+D G Y C
Sbjct: 115 DEKKVALNCEVRGNPVPSYRWLRNGTEIDLESDYRYSLIDGTFIIS-NPSEAKDSGHYQC 173
Query: 65 EASNCLGKAKS-NACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCA-VKGN 122
A+N +G S A L + S R V EG+ V C+ +
Sbjct: 174 LATNTVGSILSREATLQFAYLGNFSGRTRSAVS----------VREGQGVVLMCSPPPHS 223
Query: 123 PSPWASW--DKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRA 178
P SW ++ S + +R + ++ L I +V DVG Y V+N + A
Sbjct: 224 PEIIYSWVFNEFPSFVAEDSRRFISQE---TGNLYISKVQTSDVGSYICLVKNTVTNA 278
Score = 46.0 bits (104), Expect = 1e-04
Identities = 35/118 (29%), Positives = 51/118 (43%), Gaps = 6/118 (5%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
V EC+ G+P P I W +R+ + DG+ L+I + DEG Y C N
Sbjct: 499 VVIECKPQGSPKPTISWKKGDRAVRENKRI-AILPDGS--LRILNASKSDEGKYVCRGEN 555
Query: 69 CLGKAKSNACLVVYHTRRLS-SPGRQMAPTFYTYPFN-KVVEEGE-NVTFKCAVKGNP 123
G A+ A L V R+ +P R + N K + + +VTF +KG P
Sbjct: 556 VFGSAEIIASLSVKEPTRIELTPKRTELTVGESIVLNCKAIHDASLDVTFYWTLKGQP 613
>BC039255-1|AAH39255.1| 617|Homo sapiens CNTN5 protein protein.
Length = 617
Score = 74.9 bits (176), Expect = 2e-13
Identities = 55/188 (29%), Positives = 80/188 (42%), Gaps = 20/188 (10%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G TV+ EC GNP P I W I A S A L+I V +D G Y C
Sbjct: 21 GTTVKMECFALGNPVPTITWMKVNGYIPSKARLRKSQ----AVLEIPNVQLDDAGIYECR 76
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A N GK L VY P + + ++ G + ++C G P P
Sbjct: 77 AENSRGKNSFRGQLQVY-----------TYPHWVEKLNDTQLDSGSPLRWECKATGKPRP 125
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
W K+G ++P +R+ E + +L I V+ D G+Y+ EN+ G ASA L+
Sbjct: 126 TYRWLKNGVPLSPQSRV-----EMVNGVLMIHNVNQSDAGMYQCLAENKYGAIYASAELK 180
Query: 186 VITRSGKF 193
++ + F
Sbjct: 181 ILASAPTF 188
Score = 62.5 bits (145), Expect = 1e-09
Identities = 55/183 (30%), Positives = 76/183 (41%), Gaps = 20/183 (10%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G + +EC+ TG P P RW + +S + L I V D G Y C
Sbjct: 110 GSPLRWECKATGKPRPTYRWLKNGVPLSP----QSRVEMVNGVLMIHNVNQSDAGMYQCL 165
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNK--VVEEGENVTFKCAVKGNP 123
A N G ++A L + L+S APTF K +V + + V +C +G+P
Sbjct: 166 AENKYGAIYASAELKI-----LAS-----APTFALNQLKKTIIVTKDQEVVIECKPQGSP 215
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
P SW K + + RI + + +RIL S D G Y EN G AE A
Sbjct: 216 KPTISWKKGDRAVRENKRIAIL-PDGSLRIL---NASKSDEGKYVCRGENVFGSAEIIAS 271
Query: 184 LEV 186
L V
Sbjct: 272 LSV 274
Score = 53.2 bits (122), Expect = 7e-07
Identities = 28/88 (31%), Positives = 40/88 (45%), Gaps = 5/88 (5%)
Query: 101 YPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVS 160
+PF +G V +C GNP P +W K I AR+ + +LEI V
Sbjct: 12 FPFTVTAAKGTTVKMECFALGNPVPTITWMKVNGYIPSKARL-----RKSQAVLEIPNVQ 66
Query: 161 IEDVGIYRITVENELGRAEASARLEVIT 188
++D GIY EN G+ +L+V T
Sbjct: 67 LDDAGIYECRAENSRGKNSFRGQLQVYT 94
Score = 46.0 bits (104), Expect = 1e-04
Identities = 35/118 (29%), Positives = 51/118 (43%), Gaps = 6/118 (5%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
V EC+ G+P P I W +R+ + DG+ L+I + DEG Y C N
Sbjct: 205 VVIECKPQGSPKPTISWKKGDRAVRENKRI-AILPDGS--LRILNASKSDEGKYVCRGEN 261
Query: 69 CLGKAKSNACLVVYHTRRLS-SPGRQMAPTFYTYPFN-KVVEEGE-NVTFKCAVKGNP 123
G A+ A L V R+ +P R + N K + + +VTF +KG P
Sbjct: 262 VFGSAEIIASLSVKEPTRIELTPKRTELTVGESIVLNCKAIHDASLDVTFYWTLKGQP 319
>BC036524-1|AAH36524.1| 772|Homo sapiens DCC protein protein.
Length = 772
Score = 74.9 bits (176), Expect = 2e-13
Identities = 55/186 (29%), Positives = 83/186 (44%), Gaps = 17/186 (9%)
Query: 1 MLSCDGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEG 60
+++ +G E V+G P P W EVI+ + S G + L I VT +D G
Sbjct: 183 VVAIEGKDAVLEGCVSGYPPPSFTWLRGEEVIQLRSKKYSLL--GGSNLLISNVTDDDSG 240
Query: 61 TYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVK 120
YTC + ++A L V + P F +P N E ++ F+C V
Sbjct: 241 MYTCVVTYKNENISASAELTVL-----------VPPWFLNHPSNLYAYESMDIEFECTVS 289
Query: 121 GNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEA 180
G P P +W K+G ++ PS + +RIL + + D G Y+ ENE G A+
Sbjct: 290 GKPVPTVNWMKNGDVVIPSDYFQIVGGSN-LRILGVVK---SDEGFYQCVAENEAGNAQT 345
Query: 181 SARLEV 186
SA+L V
Sbjct: 346 SAQLIV 351
Score = 60.5 bits (140), Expect = 5e-09
Identities = 50/183 (27%), Positives = 74/183 (40%), Gaps = 9/183 (4%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
GDTV +C+V G P P I W + + + L+I ++ D G Y C
Sbjct: 88 GDTVLLKCEVIGEPMPTIHWQKNQQDLTPIPGDSRVVVLPSGALQISRLQPGDIGIYRCS 147
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A N N V R LS PG F P N V EG++ + V G P P
Sbjct: 148 ARNPASSRTGNEAEV----RILSDPGLHRQLYFLQRPSNVVAIEGKDAVLEGCVSGYPPP 203
Query: 126 WASWDKDGSII-TPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
+W + +I S + ++ ++ I V+ +D G+Y V + ASA L
Sbjct: 204 SFTWLRGEEVIQLRSKKYSLLGGSNLL----ISNVTDDDSGMYTCVVTYKNENISASAEL 259
Query: 185 EVI 187
V+
Sbjct: 260 TVL 262
Score = 45.2 bits (102), Expect = 2e-04
Identities = 39/138 (28%), Positives = 60/138 (43%), Gaps = 17/138 (12%)
Query: 58 DEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKC 117
DEG Y CEAS LG + S ++ T +++ G F + + G+ V KC
Sbjct: 45 DEGLYQCEAS--LGDSGS----IISRTAKVAVAG---PLRFLSQTESVTAFMGDTVLLKC 95
Query: 118 AVKGNPSPWASWDKDGSIITP---SARITVKEKEEIMRILEIDEVSIEDVGIYRITVENE 174
V G P P W K+ +TP +R+ V L+I + D+GIYR + N
Sbjct: 96 EVIGEPMPTIHWQKNQQDLTPIPGDSRVVVLPS----GALQISRLQPGDIGIYRCSARNP 151
Query: 175 L-GRAEASARLEVITRSG 191
R A + +++ G
Sbjct: 152 ASSRTGNEAEVRILSDPG 169
>AF156100-1|AAK68690.1| 5636|Homo sapiens hemicentin protein.
Length = 5636
Score = 74.9 bits (176), Expect = 2e-13
Identities = 55/183 (30%), Positives = 78/183 (42%), Gaps = 10/183 (5%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G V C+ +GNP P + W E+I + S+ DG+ L + E+ G Y C
Sbjct: 994 EGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGS--LYVVSPEGEESGEYVC 1051
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
A+N G AK L VY R+ R ++ P V GE VT C VK P
Sbjct: 1052 TATNTAGYAKRKVQLTVYVRPRVFGDLRGLSQD---KPVEISVLAGEEVTLPCEVKSLPP 1108
Query: 125 PWASWDKDGSIITP-SARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
P +W K+ +I+P S R T ++I E D G+Y N G + +
Sbjct: 1109 PIITWAKETQLISPFSPRHTFLPSGS----MKITETRTSDSGMYLCVATNIAGNVTQAVK 1164
Query: 184 LEV 186
L V
Sbjct: 1165 LNV 1167
Score = 74.5 bits (175), Expect = 3e-13
Identities = 48/178 (26%), Positives = 75/178 (42%), Gaps = 13/178 (7%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
V +C G P+P I W + + G L+I + ED G YTC A+N
Sbjct: 1844 VALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATN 1902
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G+ + + L V+ L G+ + N+ V V +C GNP P +
Sbjct: 1903 AAGETQQHIQLHVHEPPSLEDAGKML---------NETVLVSNPVQLECKAAGNPVPVIT 1953
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KD +++ S +T + + I++I+ I D GIY+ N G E L+V
Sbjct: 1954 WYKDNCLLSGSTSMTFLNRGQ---IIDIESAQISDAGIYKCVAINSAGATELFYSLQV 2008
Score = 71.7 bits (168), Expect = 2e-12
Identities = 57/180 (31%), Positives = 79/180 (43%), Gaps = 20/180 (11%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+ + C+ TG P P + W +I A F+S +G + L I++V+ ED GTY C
Sbjct: 4275 GEQLRLSCKATGIPLPKLTWTFNNNIIP--AHFDSV--NGHSELVIERVSKEDSGTYVCT 4330
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFY-TYPFNKVVEEGENVTFKCAVKGNPS 124
A N +G K+ + V + P F YP N + G N C VKG+P+
Sbjct: 4331 AENSVGFVKATGFVYV-----------KEPPVFKGDYPSNWIEPLGGNAILNCEVKGDPT 4379
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
P W++ G I S RI ++ L I ED G Y NE G E S L
Sbjct: 4380 PTIQWNRKGVDIEISHRI----RQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSL 4435
Score = 67.7 bits (158), Expect = 3e-11
Identities = 43/182 (23%), Positives = 79/182 (43%), Gaps = 11/182 (6%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G+ + C+ +G P P++ W + + G +L+I D Y+C
Sbjct: 2211 EGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSC 2270
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
ASN G AK L VY +++ G ++P +V G++++ +C V+G P
Sbjct: 2271 VASNVAGTAKKEYNLQVYIRPTITNSG--------SHPTEIIVTRGKSISLECEVQGIPP 2322
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
P +W KDG + + + + ++ IL++ + + D G Y N G + L
Sbjct: 2323 PTVTWMKDGHPLIKAKGVEILDEG---HILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDL 2379
Query: 185 EV 186
V
Sbjct: 2380 SV 2381
Score = 67.3 bits (157), Expect = 4e-11
Identities = 58/198 (29%), Positives = 83/198 (41%), Gaps = 19/198 (9%)
Query: 5 DGDTVEFECQV-TGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYT 63
+G + C + GNP P+ RW + ++ + + DG+ L I++V +D G YT
Sbjct: 903 EGQQLTLPCTLLAGNPIPERRWIKNSAMLLQ-NPYITVRSDGS--LHIERVQLQDGGEYT 959
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
C ASN G +VV H G+Q+ T EG VT C GNP
Sbjct: 960 CVASNVAGTNNKTTSVVV-HVLPTIQHGQQILSTI----------EGIPVTLPCKASGNP 1008
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
P W K G +I+ S + K L + E+ G Y T N G A+ +
Sbjct: 1009 KPSVIWSKKGELISTS---SAKFSAGADGSLYVVSPEGEESGEYVCTATNTAGYAKRKVQ 1065
Query: 184 LEVITRSGKFYGGLRAYS 201
L V R + +G LR S
Sbjct: 1066 LTVYVRP-RVFGDLRGLS 1082
Score = 66.5 bits (155), Expect = 7e-11
Identities = 53/174 (30%), Positives = 73/174 (41%), Gaps = 16/174 (9%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFE-SSYDD-GTARLKIKQVTAEDEGTYT 63
G V C V G P+P I+W + F SS T L I + A D+GTY
Sbjct: 807 GSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYI 866
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCA-VKGN 122
CEA N GK +S + V +AP P V EG+ +T C + GN
Sbjct: 867 CEAENQFGKIQSETTVTVTGL---------VAPLIGISPSVANVIEGQQLTLPCTLLAGN 917
Query: 123 PSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG 176
P P W K+ +++ + ITV+ L I+ V ++D G Y N G
Sbjct: 918 PIPERRWIKNSAMLLQNPYITVRSDGS----LHIERVQLQDGGEYTCVASNVAG 967
Score = 66.5 bits (155), Expect = 7e-11
Identities = 50/178 (28%), Positives = 71/178 (39%), Gaps = 13/178 (7%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
V ECQV G P PDI WF + + D D L +K D+G Y C SN
Sbjct: 1471 VALECQVKGTPFPDIHWFKDGKPL-FLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSN 1529
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
GK + L +Y + T + N +++ +C +G P P +
Sbjct: 1530 AAGKQAKDIKLTIYIPPSIKGGN---VTTDISVLINSLIK------LECKTRGLPMPAIT 1580
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KDG I S++ +K + L I + D Y V N G AE S ++V
Sbjct: 1581 WYKDGQPIMSSSQALYIDKGQ---YLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDV 1635
Score = 66.5 bits (155), Expect = 7e-11
Identities = 46/178 (25%), Positives = 74/178 (41%), Gaps = 12/178 (6%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
+ C+V+G P PD+ W + I+ + + G L+I + D G YTC A N
Sbjct: 2983 ISLTCEVSGFPPPDLSWLKNXQPIK--LNTNTLIVPGGRTLQIIRAKVSDGGEYTCIAIN 3040
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G++K L VY + + V EG +V+ +C P P +
Sbjct: 3041 XAGESKKKFSLTVYVPPSIKDHDSESLSVVN-------VREGTSVSLECESNAVPPPVIT 3093
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W K+G +IT S + + + +L I + + D G Y N GR + + L V
Sbjct: 3094 WYKNGRMITESTHVEILADGQ---MLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNV 3148
Score = 66.1 bits (154), Expect = 9e-11
Identities = 46/179 (25%), Positives = 77/179 (43%), Gaps = 13/179 (7%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
++ EC+ G P P I W+ + I + ++ Y D L I + D TYTC +N
Sbjct: 1565 IKLECKTRGLPMPAITWYKDGQPIMSSS--QALYIDKGQYLHIPRAQVSDSATYTCHVAN 1622
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G A+ + + VY + +A P NK V ++T +C GNPSP +
Sbjct: 1623 VAGTAEKSFHVDVYVPPMIEG---NLAT-----PLNKQVVIAHSLTLECNAAGNPSPILT 1674
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVI 187
W KDG + + ++ + + I+ E+ D G Y + G E ++V+
Sbjct: 1675 WLKDGVPVKANDNFRIEAGGKKLEIMSAQEI---DRGQYICVATSVAGEKEIKYEVDVL 1730
Score = 65.3 bits (152), Expect = 2e-10
Identities = 52/182 (28%), Positives = 75/182 (41%), Gaps = 14/182 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
GD EC+ +G P P ++WF +R D LKI++ D G YTC
Sbjct: 716 GDITVMECKTSGIPPPQVKWFKGDLELRPSTFL--IIDPLLGLLKIQETQDLDAGDYTCV 773
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A N G+A L V SP P F P + +E G NVT C V+G P P
Sbjct: 774 AINEAGRATGKITLDV------GSP-----PVFIQEPADVSMEIGSNVTLPCYVQGYPEP 822
Query: 126 WASWDKDGSIITPSARITVKEKEEIMR-ILEIDEVSIEDVGIYRITVENELGRAEASARL 184
W + ++ S +V ++ L I + D G Y EN+ G+ ++ +
Sbjct: 823 TIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTV 882
Query: 185 EV 186
V
Sbjct: 883 TV 884
Score = 63.7 bits (148), Expect = 5e-10
Identities = 53/181 (29%), Positives = 70/181 (38%), Gaps = 17/181 (9%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G V C TG P P I W I + + DGT L IK +D G Y C
Sbjct: 626 GSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMT-SDGT--LFIKNAAPKDAGIYGCL 682
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
ASN G K N+ L R + AP +V G+ +C G P P
Sbjct: 683 ASNSAGTDKQNSTL-----RYIE------APKLMVVQSELLVALGDITVMECKTSGIPPP 731
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
W K + PS + + + ++ +L+I E D G Y NE GRA L+
Sbjct: 732 QVKWFKGDLELRPSTFLII---DPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLD 788
Query: 186 V 186
V
Sbjct: 789 V 789
Score = 63.7 bits (148), Expect = 5e-10
Identities = 47/178 (26%), Positives = 78/178 (43%), Gaps = 14/178 (7%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
+E +C VTG+P P I W ++I + F+ + +L I Q + G Y C A+N
Sbjct: 1752 LELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNG--RKLVIAQAQVSNTGLYRCMAAN 1809
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G K + V+ + S G +VV + + V +C G P+P +
Sbjct: 1810 TAGDHKKEFEVTVHVPPTIKSSGLS----------ERVVVKYKPVALQCIANGIPNPSIT 1859
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KD + +A+ +K + R+L+I + +ED G Y N G + +L V
Sbjct: 1860 WLKDDQPVN-TAQGNLKIQSS-GRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHV 1915
Score = 63.7 bits (148), Expect = 5e-10
Identities = 47/182 (25%), Positives = 73/182 (40%), Gaps = 13/182 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G ++ EC+V G P P + W + E D+G L++K + D G Y C
Sbjct: 2308 GKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEI-LDEGHI-LQLKNIHVSDTGRYVCV 2365
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A N G L V+ + R P N V E +V+ C G P P
Sbjct: 2366 AVNVAGMTDKKYDLSVHAPPSIIGNHRS--------PENISVVEKNSVSLTCEASGIPLP 2417
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
+W KDG ++ S + + ++R++ + ++ED G Y V N G L
Sbjct: 2418 STTWFKDGWPVSLSNSVRILSGGRMLRLM---QTTMEDAGQYTCVVRNAAGEERKIFGLS 2474
Query: 186 VI 187
V+
Sbjct: 2475 VL 2476
Score = 62.9 bits (146), Expect = 8e-10
Identities = 52/182 (28%), Positives = 72/182 (39%), Gaps = 12/182 (6%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G V+ C G P P I W + + S DGT L I Q T D G YTC
Sbjct: 1185 GQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGT--LSIDQATPSDAGIYTCV 1242
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A+N G ++ L V + + P + T +V + + F C KG P P
Sbjct: 1243 ATNIAGTDETEITLHVQEPPTVED----LEPPYNTTFQERVANQ--RIEFPCPAKGTPKP 1296
Query: 126 WASWDKDGSIIT-PSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
W +G +T I++ E+ +L I V+ D G Y NE G E L
Sbjct: 1297 TIKWLHNGRELTGREPGISILEEG---TLLVIASVTPYDNGEYICVAVNEAGTTERKYNL 1353
Query: 185 EV 186
+V
Sbjct: 1354 KV 1355
Score = 61.7 bits (143), Expect = 2e-09
Identities = 47/181 (25%), Positives = 68/181 (37%), Gaps = 16/181 (8%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+ V C+V P P I W ++I + + G+ +KI + D G Y C
Sbjct: 1094 GEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGS--MKITETRTSDSGMYLCV 1151
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A+N G L V+ + P P + V+ G+ V C +G P P
Sbjct: 1152 ATNIAGNVTQAVKLNVH-----------VPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLP 1200
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
+W K GS + V + L ID+ + D GIY N G E L
Sbjct: 1201 VITWSKGGSTMLVDGEHHVSNPD---GTLSIDQATPSDAGIYTCVATNIAGTDETEITLH 1257
Query: 186 V 186
V
Sbjct: 1258 V 1258
Score = 61.7 bits (143), Expect = 2e-09
Identities = 49/179 (27%), Positives = 72/179 (40%), Gaps = 13/179 (7%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
+EF C G P P I+W H + S ++GT L I VT D G Y C A N
Sbjct: 1284 IEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEEGTL-LVIASVTPYDNGEYICVAVN 1342
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G + L V H + Q++ N V + C V+G PSP
Sbjct: 1343 EAGTTERKYNLKV-HVPPVIKDKEQVS--------NVSVLLNQLTNLFCEVEGTPSPIIM 1393
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVI 187
W KD +T S+ I +I+++ + ED G Y N G ++ ++V+
Sbjct: 1394 WYKDNVQVTESSTIQTVNNGKILKLF---RATPEDAGRYSCKAINIAGTSQKYFNIDVL 1449
Score = 61.3 bits (142), Expect = 3e-09
Identities = 50/178 (28%), Positives = 64/178 (35%), Gaps = 10/178 (5%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
V C TG P P I W + I + E G ++L+I + D G YTC ASN
Sbjct: 3170 VTLTCDATGIPPPTIAWLKNYKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASN 3229
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
GKA+ Y+ + P P + V GENV C G P+P
Sbjct: 3230 MEGKAQK------YYFLSIQVPPSVAGAEI---PSDVSVLLGENVELVCNANGIPTPLIQ 3280
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KDG I ++ L I D G Y N G + L V
Sbjct: 3281 WLKDGKPIASGETERIRVSAN-GSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNV 3337
Score = 60.5 bits (140), Expect = 5e-09
Identities = 48/169 (28%), Positives = 74/169 (43%), Gaps = 18/169 (10%)
Query: 13 CQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLGK 72
C G P P I W ++ + ++ G L ++ V ED G YTC A+N G+
Sbjct: 4191 CVADGIPTPAINWKKDNVLLANLLGKYTAEPYG--ELILENVVLEDSGFYTCVANNAAGE 4248
Query: 73 AKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKD 132
L V+ + PTF P + + +GE + C G P P +W +
Sbjct: 4249 DTHTVSLTVH-----------VLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFN 4297
Query: 133 GSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEAS 181
+II P+ +V E++ I+ VS ED G Y T EN +G +A+
Sbjct: 4298 NNII-PAHFDSVNGHSELV----IERVSKEDSGTYVCTAENSVGFVKAT 4341
Score = 58.4 bits (135), Expect = 2e-08
Identities = 47/181 (25%), Positives = 70/181 (38%), Gaps = 11/181 (6%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+ VE C G P P I+W + I + L I D G YTC
Sbjct: 3262 GENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCV 3321
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A+N G+ L VY T + + A TY V+ N+ +C G P P
Sbjct: 3322 ATNPAGEEDRIFNLNVYVTPTIRG-NKDEAEKLMTY-----VDTSINI--ECRXTGTPPP 3373
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
+W K+G + S+ I + +++RI+ + DV +Y N G L+
Sbjct: 3374 QINWLKNGLPLPLSSHIRLLAAGQVIRIV---RAQVSDVAVYTCVASNRAGVDNKHYNLQ 3430
Query: 186 V 186
V
Sbjct: 3431 V 3431
Score = 58.0 bits (134), Expect = 2e-08
Identities = 44/175 (25%), Positives = 75/175 (42%), Gaps = 15/175 (8%)
Query: 13 CQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLGK 72
C+V G P P I W+ + + + ++ ++G LK+ + T ED G Y+C+A N G
Sbjct: 1382 CEVEGTPSPIIMWYKDNVQVTESSTIQT-VNNGKI-LKLFRATPEDAGRYSCKAINIAGT 1439
Query: 73 AKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKD 132
++ Y + P + F P V +V +C VKG P P W KD
Sbjct: 1440 SQK------YFNIDVLVPPTIIGTNF---PKEVSVVLNRDVALECQVKGTPFPDIHWFKD 1490
Query: 133 GS-IITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
G + + + ++ + +L + D G Y+ TV N G+ +L +
Sbjct: 1491 GKPLFLGDPNVELLDRGQ---VLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTI 1542
Score = 57.2 bits (132), Expect = 4e-08
Identities = 49/176 (27%), Positives = 69/176 (39%), Gaps = 15/176 (8%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G +V EC+ P P I W+ +I + E D L IK+ D G Y C
Sbjct: 3074 EGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADG--QMLHIKKAEVSDTGQYVC 3131
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGEN-VTFKCAVKGNP 123
A N G+ N L VY + P R++ +VE N VT C G P
Sbjct: 3132 RAINVAGRDDKNFHLNVYVPPSIEGPEREV-----------IVETISNPVTLTCDATGIP 3180
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAE 179
P +W K+ I S + V+ + L+I D G Y N G+A+
Sbjct: 3181 PPTIAWLKNYKRIENSDSLEVRILSGGSK-LQIARSQHSDSGNYTCIASNMEGKAQ 3235
Score = 57.2 bits (132), Expect = 4e-08
Identities = 54/200 (27%), Positives = 74/200 (37%), Gaps = 29/200 (14%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSY---DDGTARLKIKQVTAEDEGTY 62
G C+V G+P P I+W R D E S+ G L I ED G Y
Sbjct: 4365 GGNAILNCEVKGDPTPTIQWN------RKGVDIEISHRIRQLGNGSLAIYGTVNEDAGDY 4418
Query: 63 TCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGN 122
TC A+N G + + L L SP P P V+ G + C G
Sbjct: 4419 TCVATNEAGVVERSMSLT------LQSP-----PIITLEPVETVINAGGKIILNCQATGE 4467
Query: 123 PSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASA 182
P P +W + G I+ R+ V L I + ED + N +G
Sbjct: 4468 PQPTITWSRQGHSISWDDRVNVLSNNS----LYIADAQKEDTSEFECVARNLMG--SVLV 4521
Query: 183 RLEVITRSGKFYGGLRAYSA 202
R+ VI + +GG +SA
Sbjct: 4522 RVPVIV---QVHGGFSQWSA 4538
Score = 56.8 bits (131), Expect = 6e-08
Identities = 48/178 (26%), Positives = 69/178 (38%), Gaps = 17/178 (9%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
+ C+ G P PDI W I + + G+ L+I V D G YTC A+N
Sbjct: 4097 ITLSCEADGLPPPDITWHKDGRAIVESIR-QRVLSSGS--LQIAFVQPGDAGHYTCMAAN 4153
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G + ++ L V+ R+ S YT V E C G P+P +
Sbjct: 4154 VAGSSSTSTKLTVHVPPRIRS-----TEGHYT------VNENSQAILPCVADGIPTPAIN 4202
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KD ++ A + K E L ++ V +ED G Y N G + L V
Sbjct: 4203 WKKDNVLL---ANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHTVSLTV 4257
Score = 56.4 bits (130), Expect = 7e-08
Identities = 49/174 (28%), Positives = 63/174 (36%), Gaps = 17/174 (9%)
Query: 13 CQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLGK 72
C+ TG P P I W + + G L+I + ED GTY C A N G
Sbjct: 4010 CEATGTPSPFITWQKEGINVNTSGRNHAVLPSGG--LQISRAVREDAGTYMCVAQNPAGT 4067
Query: 73 AKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKD 132
A L V Q+ P + V+ + +T C G P P +W KD
Sbjct: 4068 ALGKIKLNV-----------QVPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKD 4116
Query: 133 GSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
G I S R V L+I V D G Y N G + S +L V
Sbjct: 4117 GRAIVESIRQRVLSSGS----LQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTV 4166
Score = 55.6 bits (128), Expect = 1e-07
Identities = 45/180 (25%), Positives = 72/180 (40%), Gaps = 14/180 (7%)
Query: 8 TVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEAS 67
++ EC+ TG P P I W + + R+ QV+ D YTC AS
Sbjct: 3360 SINIECRXTGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVS--DVAVYTCVAS 3417
Query: 68 NCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWA 127
N G + L V+ + + M T V +G + + C G P+P
Sbjct: 3418 NRAGVDNKHYNLQVFAPPNMDN---SMGTEEIT------VLKGSSTSMACITDGTPAPSM 3468
Query: 128 SWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVI 187
+W +DG + A +TV ++++L+ + ED G Y NE G L+V+
Sbjct: 3469 AWLRDGQPLGLDAHLTVSTHGMVLQLLKAE---TEDSGKYTCIASNEAGEVSKHFILKVL 3525
Score = 54.4 bits (125), Expect = 3e-07
Identities = 43/169 (25%), Positives = 67/169 (39%), Gaps = 11/169 (6%)
Query: 8 TVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEAS 67
+V C+VTGNP P+I W + +++ D G L+I V G YTC AS
Sbjct: 2497 SVTLTCEVTGNPVPEITWHKDGQPLQE--DEAHHIISGGRFLQITNVQVPHTGRYTCLAS 2554
Query: 68 NCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWA 127
+ G + L V+ + ++ G P T N + C P
Sbjct: 2555 SPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILN------SPTSLVCEAYSYPPATI 2608
Query: 128 SWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG 176
+W KDG+ + + I + ++IL E ++ G Y NE G
Sbjct: 2609 TWFKDGTPLESNRNIRILPGGRTLQILNAQE---DNAGRYSCVATNEAG 2654
Score = 54.4 bits (125), Expect = 3e-07
Identities = 43/173 (24%), Positives = 72/173 (41%), Gaps = 10/173 (5%)
Query: 7 DTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEA 66
+T+ EC+ P + W+ + ++ + + T L+IK+ D G YTC A
Sbjct: 2691 NTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHT--LQIKEAQISDTGRYTCVA 2748
Query: 67 SNCLGKAKSNACL---VVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
SN G+ + + + V ++L G M T V+ ++ C P
Sbjct: 2749 SNIAGEDELDFDVNIQVPPSFQKLWEIG-NMLDTGRNGEAKDVIINNP-ISLYCETNAAP 2806
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG 176
P +W KDG +T S ++ + R+L+I +ED G Y NE G
Sbjct: 2807 PPTLTWYKDGHPLTSSDKVLILPGG---RVLQIPRAKVEDAGRYTCVAVNEAG 2856
Score = 53.2 bits (122), Expect = 7e-07
Identities = 47/180 (26%), Positives = 65/180 (36%), Gaps = 14/180 (7%)
Query: 7 DTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEA 66
++V C+ +G P P WF + G L++ Q T ED G YTC
Sbjct: 2403 NSVSLTCEASGIPLPSTTWFKDGWPVSLSNSVRIL--SGGRMLRLMQTTMEDAGQYTCVV 2460
Query: 67 SNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPW 126
N G+ + ++ L P T V+E ++VT C V GNP P
Sbjct: 2461 RNAAGEERK-----IFGLSVLVPPHIVGENTLEDVK----VKEKQSVTLTCEVTGNPVPE 2511
Query: 127 ASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
+W KDG P R L+I V + G Y + G S L V
Sbjct: 2512 ITWHKDGQ---PLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNV 2568
Score = 52.8 bits (121), Expect = 9e-07
Identities = 40/171 (23%), Positives = 63/171 (36%), Gaps = 15/171 (8%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
V EC+ G P P + W + ++ G L + D G YTC A N
Sbjct: 2029 VRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRI-LALTSTQISDTGRYTCVAVN 2087
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G+ + + L VY + P N V + V C P P +
Sbjct: 2088 AAGEKQRDIDLRVY-----------VPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLT 2136
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAE 179
W KDG + +++ E +L+I++ ++D G Y N G+ E
Sbjct: 2137 WLKDGHPLLKKPGLSISENRS---VLKIEDAQVQDTGRYTCEATNVAGKTE 2184
Score = 52.8 bits (121), Expect = 9e-07
Identities = 49/184 (26%), Positives = 70/184 (38%), Gaps = 17/184 (9%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
VE CQ P P + W + S + + LKI+ +D G YTCEA+N
Sbjct: 2121 VELLCQSDAIPPPTLTWLKDGHPLLKKPGL--SISENRSVLKIEDAQVQDTGRYTCEATN 2178
Query: 69 CLGKA-KSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWA 127
GK K N + ++ + T V EG ++ C G P P
Sbjct: 2179 VAGKTEKKNYNVNIWVPPNIGGSDELTQLT---------VIEGNLISLLCESSGIPPPNL 2229
Query: 128 SWDKDGS-IITPS-ARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
W K GS ++T S R+ + R L+I D +Y N G A+ L+
Sbjct: 2230 IWKKKGSPVLTDSMGRVRILSGG---RQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQ 2286
Query: 186 VITR 189
V R
Sbjct: 2287 VYIR 2290
Score = 52.8 bits (121), Expect = 9e-07
Identities = 46/179 (25%), Positives = 67/179 (37%), Gaps = 18/179 (10%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
V EC+ P P I W E ++ A G L+I D YTC ASN
Sbjct: 3640 VTLECKSDAVPPPVITWLRNGERLQ--ATPRVRILSGGRYLQINNADLGDTANYTCVASN 3697
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
GK L V + P P + V+ ++ +C +G P+P +
Sbjct: 3698 IAGKTTREFILTV-----------NVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRIT 3746
Query: 129 WDKDGSIITPS-ARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KDG+++ + AR ++ E L I + D G Y N G L+V
Sbjct: 3747 WRKDGAVLAGNHARYSILEN----GFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQV 3801
Score = 52.4 bits (120), Expect = 1e-06
Identities = 47/178 (26%), Positives = 68/178 (38%), Gaps = 12/178 (6%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
+ C+ P P + W+ + +D G L+I + ED G YTC A N
Sbjct: 2796 ISLYCETNAAPPPTLTWYKDGHPLTS-SDKVLILPGGRV-LQIPRAKVEDAGRYTCVAVN 2853
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G+ + Y R L P + A + P V ++ +C G+P+P S
Sbjct: 2854 EAGEDS-----LQYDVRVLVPPIIEGANS--DLPEEVTVLVNKSALIECLSSGSPAPRNS 2906
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KDG + RIL+I I D+G Y EN G A+ L V
Sbjct: 2907 WQKDGQPLLEDDHHKFLSNG---RILQILNTQITDIGRYVCVAENTAGSAKKYFNLNV 2961
Score = 49.6 bits (113), Expect = 8e-06
Identities = 46/179 (25%), Positives = 67/179 (37%), Gaps = 17/179 (9%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
V+ EC+ GNP P I W Y + ++ + + I+ D G Y C A N
Sbjct: 1938 VQLECKAAGNPVPVITW--YKDNCLLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAIN 1995
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G + L V+ +S +A V V +C +G P+P +
Sbjct: 1996 SAGATELFYSLQVHVAPSISGSNNMVA-----------VVVNNPVRLECEARGIPAPSLT 2044
Query: 129 WDKDGSIITP-SARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KDGS ++ S + V RIL + I D G Y N G + L V
Sbjct: 2045 WLKDGSPVSSFSNGLQVLSGG---RILALTSTQISDTGRYTCVAVNAAGEKQRDIDLRV 2100
Score = 48.8 bits (111), Expect = 1e-05
Identities = 40/171 (23%), Positives = 67/171 (39%), Gaps = 18/171 (10%)
Query: 8 TVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEAS 67
++ EC GNP P + W ++ +F + G +L+I D G Y C A+
Sbjct: 1658 SLTLECNAAGNPSPILTWLKDGVPVKANDNFR--IEAGGKKLEIMSAQEIDRGQYICVAT 1715
Query: 68 NCLGKAKSNACLVVYHTRRLSSPGRQMA--PTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
+ G+ + + Y L P + +++ N ++E C V G+P P
Sbjct: 1716 SVAGEKE-----IKYEVDVLVPPAIEGGDETSYFIVMVNNLLE------LDCHVTGSPPP 1764
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG 176
W KDG +I + R L I + + + G+YR N G
Sbjct: 1765 TIMWLKDGQLIDERDGFKILLNG---RKLVIAQAQVSNTGLYRCMAANTAG 1812
Score = 47.6 bits (108), Expect = 3e-05
Identities = 43/174 (24%), Positives = 57/174 (32%), Gaps = 16/174 (9%)
Query: 13 CQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLGK 72
C +G P P I W + D G + Q+ G YTC A N G
Sbjct: 3919 CTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQLN--HAGRYTCVARNAAGS 3976
Query: 73 AKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKD 132
A + L V+ P P V + C G PSP+ +W K+
Sbjct: 3977 AHRHVTLHVHEP-----------PVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKE 4025
Query: 133 GSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
G + S R L+I ED G Y +N G A +L V
Sbjct: 4026 GINVNTSGR---NHAVLPSGGLQISRAVREDAGTYMCVAQNPAGTALGKIKLNV 4076
Score = 47.2 bits (107), Expect = 4e-05
Identities = 48/180 (26%), Positives = 67/180 (37%), Gaps = 24/180 (13%)
Query: 12 ECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLG 71
EC G P P I W V+ S ++G ++ VT D G Y C A+N G
Sbjct: 3734 ECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLHIQSAHVT--DTGRYLCMATNAAG 3791
Query: 72 KAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDK 131
+ L V H +PG P N V T C G P P +W K
Sbjct: 3792 TDRRRIDLQV-HVPPSIAPG----------PTNMTVIVNVQTTLACEATGIPKPSINWRK 3840
Query: 132 DGSIITPSARITVKEKEEIMRILE-----IDEVSIEDVGIYRITVENELGRAEASARLEV 186
+G + + V + + R+L I S++D Y TV N G + + L V
Sbjct: 3841 NGHL------LNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGDDKRTVDLTV 3894
Score = 46.8 bits (106), Expect = 6e-05
Identities = 38/171 (22%), Positives = 63/171 (36%), Gaps = 14/171 (8%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G + C G P P + W + + D + L++ + ED G YTC
Sbjct: 3451 GSSTSMACITDGTPAPSMAWLRDGQPLG--LDAHLTVSTHGMVLQLLKAETEDSGKYTCI 3508
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
ASN G+ + L V ++ + +V +T C G P+P
Sbjct: 3509 ASNEAGEVSKHFILKVLEPPHINGSEEHEE-------ISVIVNNPLELT--CIASGIPAP 3559
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG 176
+W KDG + + ++ E++R I +ED G Y + G
Sbjct: 3560 KMTWMKDGRPLPQTDQVQTLGGGEVLR---ISTAQVEDTGRYTCLASSPAG 3607
Score = 42.3 bits (95), Expect = 0.001
Identities = 41/176 (23%), Positives = 60/176 (34%), Gaps = 18/176 (10%)
Query: 13 CQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLGK 72
C+ TG P P I W ++ + S + L I + +D TY C +N G
Sbjct: 3826 CEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGD 3885
Query: 73 AKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKD 132
K L V Q+ P+ P + +V + C G P P W K+
Sbjct: 3886 DKRTVDLTV-----------QVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKN 3934
Query: 133 GSIITPSARITVKEKEEIMR--ILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
G + P + I+ +EI + G Y N G A L V
Sbjct: 3935 GIRLLPRG-----DGYRILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHV 3985
Score = 41.9 bits (94), Expect = 0.002
Identities = 38/167 (22%), Positives = 59/167 (35%), Gaps = 8/167 (4%)
Query: 13 CQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLGK 72
C+ P I WF + + G L+I ++ G Y+C A+N G+
Sbjct: 2598 CEAYSYPPATITWFKDGTPLESNRNIRIL--PGGRTLQILNAQEDNAGRYSCVATNEAGE 2655
Query: 73 AKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKD 132
+ + VY + + G P P ++ +T +C PS SW KD
Sbjct: 2656 MIKHYEVKVY-IPPIINKGDLWGPGLS--PKEVKIKVNNTLTLECEAYAIPSASLSWYKD 2712
Query: 133 GSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAE 179
G + + + L+I E I D G Y N G E
Sbjct: 2713 GQPLKSDDHVNIAANG---HTLQIKEAQISDTGRYTCVASNIAGEDE 2756
Score = 40.7 bits (91), Expect = 0.004
Identities = 36/169 (21%), Positives = 61/169 (36%), Gaps = 14/169 (8%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
+E C +G P P + W + ++ G L+I ED G YTC AS+
Sbjct: 3547 LELTCIASGIPAPKMTWMKDGRPLPQTDQVQTL--GGGEVLRISTAQVEDTGRYTCLASS 3604
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G + V+ ++ P + V VT +C P P +
Sbjct: 3605 PAGDDDKEYLVRVHVPPNIAGTDE---------PRDITVLRNRQVTLECKSDAVPPPVIT 3655
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGR 177
W ++G + + R+ + R L+I+ + D Y N G+
Sbjct: 3656 WLRNGERLQATPRVRILSGG---RYLQINNADLGDTANYTCVASNIAGK 3701
Score = 40.3 bits (90), Expect = 0.005
Identities = 34/139 (24%), Positives = 52/139 (37%), Gaps = 15/139 (10%)
Query: 49 LKIKQVTAEDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVE 108
L++K V D G Y C S+ G + ++ L V Q P P N+
Sbjct: 576 LELKSVKFNDAGEYHCMVSSEGGSSAASVFLTV-----------QEPPKVTVMPKNQSFT 624
Query: 109 EGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYR 168
G V+ C+ G P P +W + I S R + + I + +D GIY
Sbjct: 625 GGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGTLF----IKNAAPKDAGIYG 680
Query: 169 ITVENELGRAEASARLEVI 187
N G + ++ L I
Sbjct: 681 CLASNSAGTDKQNSTLRYI 699
Score = 39.1 bits (87), Expect = 0.012
Identities = 43/175 (24%), Positives = 62/175 (35%), Gaps = 15/175 (8%)
Query: 12 ECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLG 71
EC +G+P P W + + + D +G L+I D G Y C A N G
Sbjct: 2894 ECLSSGSPAPRNSWQKDGQPLLE-DDHHKFLSNGRI-LQILNTQITDIGRYVCVAENTAG 2951
Query: 72 KAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDK 131
AK L V+ + P + N V ++ C V G P P SW K
Sbjct: 2952 SAKKYFNLNVHVPPSVIGPKSE----------NLTVVVNNFISLTCEVSGFPPPDLSWLK 3001
Query: 132 DGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
+ I + + R L+I + D G Y N G ++ L V
Sbjct: 3002 NXQPIKLNTNTLIVPGG---RTLQIIRAKVSDGGEYTCIAINXAGESKKKFSLTV 3053
Score = 38.7 bits (86), Expect = 0.016
Identities = 35/144 (24%), Positives = 53/144 (36%), Gaps = 13/144 (9%)
Query: 43 DDGTARLKIKQVTAEDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYP 102
+ + L I +VT DEG Y C A + G ++ V S P P P
Sbjct: 478 ESASVSLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDV------SEP-----PPVIQVP 526
Query: 103 FNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIE 162
N V GE C + +W ++ + + ++ + LE+ V
Sbjct: 527 NNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLS--LELKSVKFN 584
Query: 163 DVGIYRITVENELGRAEASARLEV 186
D G Y V +E G + AS L V
Sbjct: 585 DAGEYHCMVSSEGGSSAASVFLTV 608
>AB013803-1|BAA36580.2| 1026|Homo sapiens hNB-2s protein.
Length = 1026
Score = 74.9 bits (176), Expect = 2e-13
Identities = 55/188 (29%), Positives = 80/188 (42%), Gaps = 20/188 (10%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G TV+ EC GNP P I W I A S A L+I V +D G Y C
Sbjct: 241 GTTVKMECFALGNPVPTITWMKVNGYIPSKARLRKSQ----AVLEIPNVQLDDAGIYECR 296
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A N GK L VY P + + ++ G + ++C G P P
Sbjct: 297 AENSRGKNSFRGQLQVY-----------TYPHWVEKLNDTQLDSGSPLRWECKATGKPRP 345
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
W K+G ++P +R+ E + +L I V+ D G+Y+ EN+ G ASA L+
Sbjct: 346 TYRWLKNGVPLSPQSRV-----EMVNGVLMIHNVNQSDAGMYQCLAENKYGAIYASAELK 400
Query: 186 VITRSGKF 193
++ + F
Sbjct: 401 ILASAPTF 408
Score = 62.5 bits (145), Expect = 1e-09
Identities = 40/143 (27%), Positives = 57/143 (39%), Gaps = 5/143 (3%)
Query: 46 TARLKIKQVTAEDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNK 105
T L I +V D G+Y C N + A+ + R G +PF
Sbjct: 177 TGNLYISKVQTSDVGSYICLVKNTVTNARVLSPPTPLTLRNDGVMGEYEPKIEVHFPFTV 236
Query: 106 VVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVG 165
+G V +C GNP P +W K I AR+ + +LEI V ++D G
Sbjct: 237 TAAKGTTVKMECFALGNPVPTITWMKVNGYIPSKARL-----RKSQAVLEIPNVQLDDAG 291
Query: 166 IYRITVENELGRAEASARLEVIT 188
IY EN G+ +L+V T
Sbjct: 292 IYECRAENSRGKNSFRGQLQVYT 314
Score = 62.5 bits (145), Expect = 1e-09
Identities = 55/183 (30%), Positives = 76/183 (41%), Gaps = 20/183 (10%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G + +EC+ TG P P RW + +S + L I V D G Y C
Sbjct: 330 GSPLRWECKATGKPRPTYRWLKNGVPLSP----QSRVEMVNGVLMIHNVNQSDAGMYQCL 385
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNK--VVEEGENVTFKCAVKGNP 123
A N G ++A L + L+S APTF K +V + + V +C +G+P
Sbjct: 386 AENKYGAIYASAELKI-----LAS-----APTFALNQLKKTIIVTKDQEVVIECKPQGSP 435
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
P SW K + + RI + + +RIL S D G Y EN G AE A
Sbjct: 436 KPTISWKKGDRAVRENKRIAIL-PDGSLRIL---NASKSDEGKYVCRGENVFGSAEIIAS 491
Query: 184 LEV 186
L V
Sbjct: 492 LSV 494
Score = 46.8 bits (106), Expect = 6e-05
Identities = 49/178 (27%), Positives = 70/178 (39%), Gaps = 18/178 (10%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
D V C+V GNP P RW I +D+ S DGT + A+D G Y C
Sbjct: 41 DEKKVALNCEVRGNPVPSYRWLRNGTEIDLESDYRYSLIDGTFIIS-NPSEAKDSGHYQC 99
Query: 65 EASNCLGKAKS-NACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCA-VKGN 122
A+N +G S A L + S R V EG+ V C+ +
Sbjct: 100 LATNTVGSILSREATLQFAYLGNFSGRTRSAVS----------VREGQGVVLMCSPPPHS 149
Query: 123 PSPWASW--DKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRA 178
P SW ++ S + +R + ++ L I +V DVG Y V+N + A
Sbjct: 150 PEIIYSWVFNEFPSFVAEDSRRFISQE---TGNLYISKVQTSDVGSYICLVKNTVTNA 204
Score = 46.0 bits (104), Expect = 1e-04
Identities = 35/118 (29%), Positives = 51/118 (43%), Gaps = 6/118 (5%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
V EC+ G+P P I W +R+ + DG+ L+I + DEG Y C N
Sbjct: 425 VVIECKPQGSPKPTISWKKGDRAVRENKRI-AILPDGS--LRILNASKSDEGKYVCRGEN 481
Query: 69 CLGKAKSNACLVVYHTRRLS-SPGRQMAPTFYTYPFN-KVVEEGE-NVTFKCAVKGNP 123
G A+ A L V R+ +P R + N K + + +VTF +KG P
Sbjct: 482 VFGSAEIIASLSVKEPTRIELTPKRTELTVGESIVLNCKAIHDASLDVTFYWTLKGQP 539
>AB013802-1|BAA36579.2| 1100|Homo sapiens hNB-2 protein.
Length = 1100
Score = 74.9 bits (176), Expect = 2e-13
Identities = 55/188 (29%), Positives = 80/188 (42%), Gaps = 20/188 (10%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G TV+ EC GNP P I W I A S A L+I V +D G Y C
Sbjct: 315 GTTVKMECFALGNPVPTITWMKVNGYIPSKARLRKSQ----AVLEIPNVQLDDAGIYECR 370
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A N GK L VY P + + ++ G + ++C G P P
Sbjct: 371 AENSRGKNSFRGQLQVY-----------TYPHWVEKLNDTQLDSGSPLRWECKATGKPRP 419
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
W K+G ++P +R+ E + +L I V+ D G+Y+ EN+ G ASA L+
Sbjct: 420 TYRWLKNGVPLSPQSRV-----EMVNGVLMIHNVNQSDAGMYQCLAENKYGAIYASAELK 474
Query: 186 VITRSGKF 193
++ + F
Sbjct: 475 ILASAPTF 482
Score = 62.5 bits (145), Expect = 1e-09
Identities = 40/143 (27%), Positives = 57/143 (39%), Gaps = 5/143 (3%)
Query: 46 TARLKIKQVTAEDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNK 105
T L I +V D G+Y C N + A+ + R G +PF
Sbjct: 251 TGNLYISKVQTSDVGSYICLVKNTVTNARVLSPPTPLTLRNDGVMGEYEPKIEVHFPFTV 310
Query: 106 VVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVG 165
+G V +C GNP P +W K I AR+ + +LEI V ++D G
Sbjct: 311 TAAKGTTVKMECFALGNPVPTITWMKVNGYIPSKARL-----RKSQAVLEIPNVQLDDAG 365
Query: 166 IYRITVENELGRAEASARLEVIT 188
IY EN G+ +L+V T
Sbjct: 366 IYECRAENSRGKNSFRGQLQVYT 388
Score = 62.5 bits (145), Expect = 1e-09
Identities = 55/183 (30%), Positives = 76/183 (41%), Gaps = 20/183 (10%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G + +EC+ TG P P RW + +S + L I V D G Y C
Sbjct: 404 GSPLRWECKATGKPRPTYRWLKNGVPLSP----QSRVEMVNGVLMIHNVNQSDAGMYQCL 459
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNK--VVEEGENVTFKCAVKGNP 123
A N G ++A L + L+S APTF K +V + + V +C +G+P
Sbjct: 460 AENKYGAIYASAELKI-----LAS-----APTFALNQLKKTIIVTKDQEVVIECKPQGSP 509
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
P SW K + + RI + + +RIL S D G Y EN G AE A
Sbjct: 510 KPTISWKKGDRAVRENKRIAIL-PDGSLRIL---NASKSDEGKYVCRGENVFGSAEIIAS 565
Query: 184 LEV 186
L V
Sbjct: 566 LSV 568
Score = 46.8 bits (106), Expect = 6e-05
Identities = 49/178 (27%), Positives = 70/178 (39%), Gaps = 18/178 (10%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
D V C+V GNP P RW I +D+ S DGT + A+D G Y C
Sbjct: 115 DEKKVALNCEVRGNPVPSYRWLRNGTEIDLESDYRYSLIDGTFIIS-NPSEAKDSGHYQC 173
Query: 65 EASNCLGKAKS-NACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCA-VKGN 122
A+N +G S A L + S R V EG+ V C+ +
Sbjct: 174 LATNTVGSILSREATLQFAYLGNFSGRTRSAVS----------VREGQGVVLMCSPPPHS 223
Query: 123 PSPWASW--DKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRA 178
P SW ++ S + +R + ++ L I +V DVG Y V+N + A
Sbjct: 224 PEIIYSWVFNEFPSFVAEDSRRFISQE---TGNLYISKVQTSDVGSYICLVKNTVTNA 278
Score = 46.0 bits (104), Expect = 1e-04
Identities = 35/118 (29%), Positives = 51/118 (43%), Gaps = 6/118 (5%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
V EC+ G+P P I W +R+ + DG+ L+I + DEG Y C N
Sbjct: 499 VVIECKPQGSPKPTISWKKGDRAVRENKRI-AILPDGS--LRILNASKSDEGKYVCRGEN 555
Query: 69 CLGKAKSNACLVVYHTRRLS-SPGRQMAPTFYTYPFN-KVVEEGE-NVTFKCAVKGNP 123
G A+ A L V R+ +P R + N K + + +VTF +KG P
Sbjct: 556 VFGSAEIIASLSVKEPTRIELTPKRTELTVGESIVLNCKAIHDASLDVTFYWTLKGQP 613
>Z21488-1|CAA79696.1| 1018|Homo sapiens contactin protein.
Length = 1018
Score = 74.5 bits (175), Expect = 3e-13
Identities = 58/188 (30%), Positives = 82/188 (43%), Gaps = 28/188 (14%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G V EC GNP PDIRW E + A+ +S A LKI + EDEG Y CE
Sbjct: 256 GQNVTLECFALGNPVPDIRWRKVLEPMPSTAEISTS----GAVLKIFNIQLEDEGIYECE 311
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A N GK K A + V Q P + + + V+ G ++ + C G P P
Sbjct: 312 AENIRGKDKHQARIYV-----------QAFPEWVEHINDTEVDIGSDLYWPCVATGKPIP 360
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
W K+G K E L + +V+ E+ G+Y+ EN G A+A L+
Sbjct: 361 TIRWLKNG---------YAYHKGE----LRLYDVTFENAGMYQCIAENTYGAIYANAELK 407
Query: 186 VITRSGKF 193
++ + F
Sbjct: 408 ILALAPTF 415
Score = 56.0 bits (129), Expect = 1e-07
Identities = 56/203 (27%), Positives = 86/203 (42%), Gaps = 20/203 (9%)
Query: 1 MLSCDGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEG 60
+L+ G V EC+ P P W E + + + ++DG+ L+I +T D G
Sbjct: 424 ILAAKGGRVIIECKPKAAPKPKFSWSKGTEWLVNSSRI-LIWEDGS--LEINNITRNDGG 480
Query: 61 TYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVK 120
YTC A N GKA S LV+ + P R P N + GEN T +CA
Sbjct: 481 IYTCFAENNRGKANSTGTLVI------TDPTR-----IILAPINADITVGENATMQCAAS 529
Query: 121 GNPSPWAS--WDKDGSIITPSARITVKEKEEIMRI---LEIDEVSIEDVGIYRITVENEL 175
+P+ + W +G +I + ++ ++ L I ++ G Y T + +
Sbjct: 530 FDPALDLTFVWSFNGYVIDFNKENIHYQRNFMLDSNGELLIRNAQLKHAGRYTCTAQTIV 589
Query: 176 GRAEASARLEVITRSGKFYGGLR 198
+ ASA L V G GGLR
Sbjct: 590 DNSSASADLVVRGPPGP-PGGLR 611
Score = 47.6 bits (108), Expect = 3e-05
Identities = 42/141 (29%), Positives = 62/141 (43%), Gaps = 12/141 (8%)
Query: 49 LKIKQVTAEDEGTYTCEASN-CLGKAK-SNACLVVYHTRRLSSPGRQMAPTFYTYPFNKV 106
L I V A D+G Y+C S+ + K+ S ++ R + P P F V
Sbjct: 196 LYIANVEASDKGNYSCFVSSPSITKSVFSKFIPLIPIPERTTKP----YPADIVVQFKDV 251
Query: 107 VE-EGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVG 165
G+NVT +C GNP P W K + +A I+ +L+I + +ED G
Sbjct: 252 YALMGQNVTLECFALGNPVPDIRWRKVLEPMPSTAEISTSG-----AVLKIFNIQLEDEG 306
Query: 166 IYRITVENELGRAEASARLEV 186
IY EN G+ + AR+ V
Sbjct: 307 IYECEAENIRGKDKHQARIYV 327
>U07820-1|AAA67921.1| 1007|Homo sapiens h-contactin 2 precursor
protein.
Length = 1007
Score = 74.5 bits (175), Expect = 3e-13
Identities = 58/188 (30%), Positives = 82/188 (43%), Gaps = 28/188 (14%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G V EC GNP PDIRW E + A+ +S A LKI + EDEG Y CE
Sbjct: 245 GQNVTLECFALGNPVPDIRWRKVLEPMPSTAEISTS----GAVLKIFNIQLEDEGIYECE 300
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A N GK K A + V Q P + + + V+ G ++ + C G P P
Sbjct: 301 AENIRGKDKHQARIYV-----------QAFPEWVEHINDTEVDIGSDLYWPCVATGKPIP 349
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
W K+G K E L + +V+ E+ G+Y+ EN G A+A L+
Sbjct: 350 TIRWLKNG---------YAYHKGE----LRLYDVTFENAGMYQCIAENTYGAIYANAELK 396
Query: 186 VITRSGKF 193
++ + F
Sbjct: 397 ILALAPTF 404
Score = 56.0 bits (129), Expect = 1e-07
Identities = 56/203 (27%), Positives = 86/203 (42%), Gaps = 20/203 (9%)
Query: 1 MLSCDGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEG 60
+L+ G V EC+ P P W E + + + ++DG+ L+I +T D G
Sbjct: 413 ILAAKGGRVIIECKPKAAPKPKFSWSKGTEWLVNSSRI-LIWEDGS--LEINNITRNDGG 469
Query: 61 TYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVK 120
YTC A N GKA S LV+ + P R P N + GEN T +CA
Sbjct: 470 IYTCFAENNRGKANSTGTLVI------TDPTR-----IILAPINADITVGENATMQCAAS 518
Query: 121 GNPSPWAS--WDKDGSIITPSARITVKEKEEIMRI---LEIDEVSIEDVGIYRITVENEL 175
+P+ + W +G +I + ++ ++ L I ++ G Y T + +
Sbjct: 519 FDPALDLTFVWSFNGYVIDFNKENIHYQRNFMLDSNGELLIRNAQLKHAGRYTCTAQTIV 578
Query: 176 GRAEASARLEVITRSGKFYGGLR 198
+ ASA L V G GGLR
Sbjct: 579 DNSSASADLVVRGPPGP-PGGLR 600
Score = 47.6 bits (108), Expect = 3e-05
Identities = 42/141 (29%), Positives = 62/141 (43%), Gaps = 12/141 (8%)
Query: 49 LKIKQVTAEDEGTYTCEASN-CLGKAK-SNACLVVYHTRRLSSPGRQMAPTFYTYPFNKV 106
L I V A D+G Y+C S+ + K+ S ++ R + P P F V
Sbjct: 185 LYIANVEASDKGNYSCFVSSPSITKSVFSKFIPLIPIPERTTKP----YPADIVVQFKDV 240
Query: 107 VE-EGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVG 165
G+NVT +C GNP P W K + +A I+ +L+I + +ED G
Sbjct: 241 YALMGQNVTLECFALGNPVPDIRWRKVLEPMPSTAEISTSG-----AVLKIFNIQLEDEG 295
Query: 166 IYRITVENELGRAEASARLEV 186
IY EN G+ + AR+ V
Sbjct: 296 IYECEAENIRGKDKHQARIYV 316
>U07819-1|AAA67920.1| 1018|Homo sapiens h-contactin 1 precursor
protein.
Length = 1018
Score = 74.5 bits (175), Expect = 3e-13
Identities = 58/188 (30%), Positives = 82/188 (43%), Gaps = 28/188 (14%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G V EC GNP PDIRW E + A+ +S A LKI + EDEG Y CE
Sbjct: 256 GQNVTLECFALGNPVPDIRWRKVLEPMPSTAEISTS----GAVLKIFNIQLEDEGIYECE 311
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A N GK K A + V Q P + + + V+ G ++ + C G P P
Sbjct: 312 AENIRGKDKHQARIYV-----------QAFPEWVEHINDTEVDIGSDLYWPCVATGKPIP 360
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
W K+G K E L + +V+ E+ G+Y+ EN G A+A L+
Sbjct: 361 TIRWLKNG---------YAYHKGE----LRLYDVTFENAGMYQCIAENTYGAIYANAELK 407
Query: 186 VITRSGKF 193
++ + F
Sbjct: 408 ILALAPTF 415
Score = 56.0 bits (129), Expect = 1e-07
Identities = 56/203 (27%), Positives = 86/203 (42%), Gaps = 20/203 (9%)
Query: 1 MLSCDGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEG 60
+L+ G V EC+ P P W E + + + ++DG+ L+I +T D G
Sbjct: 424 ILAAKGGRVIIECKPKAAPKPKFSWSKGTEWLVNSSRI-LIWEDGS--LEINNITRNDGG 480
Query: 61 TYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVK 120
YTC A N GKA S LV+ + P R P N + GEN T +CA
Sbjct: 481 IYTCFAENNRGKANSTGTLVI------TDPTR-----IILAPINADITVGENATMQCAAS 529
Query: 121 GNPSPWAS--WDKDGSIITPSARITVKEKEEIMRI---LEIDEVSIEDVGIYRITVENEL 175
+P+ + W +G +I + ++ ++ L I ++ G Y T + +
Sbjct: 530 FDPALDLTFVWSFNGYVIDFNKENIHYQRNFMLDSNGELLIRNAQLKHAGRYTCTAQTIV 589
Query: 176 GRAEASARLEVITRSGKFYGGLR 198
+ ASA L V G GGLR
Sbjct: 590 DNSSASADLVVRGPPGP-PGGLR 611
Score = 47.6 bits (108), Expect = 3e-05
Identities = 42/141 (29%), Positives = 62/141 (43%), Gaps = 12/141 (8%)
Query: 49 LKIKQVTAEDEGTYTCEASN-CLGKAK-SNACLVVYHTRRLSSPGRQMAPTFYTYPFNKV 106
L I V A D+G Y+C S+ + K+ S ++ R + P P F V
Sbjct: 196 LYIANVEASDKGNYSCFVSSPSITKSVFSKFIPLIPIPERTTKP----YPADIVVQFKDV 251
Query: 107 VE-EGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVG 165
G+NVT +C GNP P W K + +A I+ +L+I + +ED G
Sbjct: 252 YALMGQNVTLECFALGNPVPDIRWRKVLEPMPSTAEISTSG-----AVLKIFNIQLEDEG 306
Query: 166 IYRITVENELGRAEASARLEV 186
IY EN G+ + AR+ V
Sbjct: 307 IYECEAENIRGKDKHQARIYV 327
>BC036569-1|AAH36569.1| 627|Homo sapiens CNTN1 protein protein.
Length = 627
Score = 74.5 bits (175), Expect = 3e-13
Identities = 58/188 (30%), Positives = 82/188 (43%), Gaps = 28/188 (14%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G V EC GNP PDIRW E + A+ +S A LKI + EDEG Y CE
Sbjct: 256 GQNVTLECFALGNPVPDIRWRKVLEPMPSTAEISTS----GAVLKIFNIQLEDEGIYECE 311
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A N GK K A + V Q P + + + V+ G ++ + C G P P
Sbjct: 312 AENIRGKDKHQARIYV-----------QAFPEWVEHINDTEVDIGSDLYWPCVATGKPIP 360
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
W K+G K E L + +V+ E+ G+Y+ EN G A+A L+
Sbjct: 361 TIRWLKNG---------YAYHKGE----LRLYDVTFENAGMYQCIAENTYGAIYANAELK 407
Query: 186 VITRSGKF 193
++ + F
Sbjct: 408 ILALAPTF 415
Score = 54.8 bits (126), Expect = 2e-07
Identities = 52/197 (26%), Positives = 84/197 (42%), Gaps = 19/197 (9%)
Query: 1 MLSCDGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEG 60
+L+ G V EC+ P P W E + + + ++DG+ L+I +T D G
Sbjct: 424 ILAAKGGRVIIECKPKAAPKPKFSWSKGTEWLVNSSRI-LIWEDGS--LEINNITRNDGG 480
Query: 61 TYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVK 120
YTC A N GKA S LV+ + P R P N + GEN T +CA
Sbjct: 481 IYTCFAENNRGKANSTGTLVI------TDPTR-----IILAPINADITVGENATMQCAAS 529
Query: 121 GNPSPWAS--WDKDGSIITPSARITVKEKEEIMRI---LEIDEVSIEDVGIYRITVENEL 175
+P+ + W +G +I + ++ ++ L I ++ G Y T + +
Sbjct: 530 FDPALDLTFVWSFNGYVIDFNKENIHYQRNFMLDSNGELLIRNAQLKHAGRYTCTAQTIV 589
Query: 176 GRAEASARLEVITRSGK 192
+ ASA L V ++ K
Sbjct: 590 DNSSASADLVVRGKNRK 606
Score = 47.6 bits (108), Expect = 3e-05
Identities = 42/141 (29%), Positives = 62/141 (43%), Gaps = 12/141 (8%)
Query: 49 LKIKQVTAEDEGTYTCEASN-CLGKAK-SNACLVVYHTRRLSSPGRQMAPTFYTYPFNKV 106
L I V A D+G Y+C S+ + K+ S ++ R + P P F V
Sbjct: 196 LYIANVEASDKGNYSCFVSSPSITKSVFSKFIPLIPIPERTTKP----YPADIVVQFKDV 251
Query: 107 VE-EGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVG 165
G+NVT +C GNP P W K + +A I+ +L+I + +ED G
Sbjct: 252 YALMGQNVTLECFALGNPVPDIRWRKVLEPMPSTAEISTSG-----AVLKIFNIQLEDEG 306
Query: 166 IYRITVENELGRAEASARLEV 186
IY EN G+ + AR+ V
Sbjct: 307 IYECEAENIRGKDKHQARIYV 327
>AK056557-1|BAB71216.1| 1252|Homo sapiens protein ( Homo sapiens
cDNA FLJ31995 fis, clone NT2RP7009236, weakly similar to
BASEMENT MEMBRANE-SPECIFIC HEPARAN SULFATE PROTEOGLYCAN
CORE ).
Length = 1252
Score = 74.5 bits (175), Expect = 3e-13
Identities = 55/183 (30%), Positives = 78/183 (42%), Gaps = 10/183 (5%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G V C+ +GNP P + W E+I + S+ DG+ L + E+ G Y C
Sbjct: 65 EGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGS--LYVVSPGGEESGEYVC 122
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
A+N G AK L VY R+ R ++ P V GE VT C VK P
Sbjct: 123 TATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQD---KPVEISVLAGEEVTLPCEVKSLPP 179
Query: 125 PWASWDKDGSIITP-SARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
P +W K+ +I+P S R T ++I E D G+Y N G + +
Sbjct: 180 PIITWAKETQLISPFSPRHTFLPSGS----MKITETRTSDSGMYLCVAINIAGNVTQAVK 235
Query: 184 LEV 186
L V
Sbjct: 236 LNV 238
Score = 74.5 bits (175), Expect = 3e-13
Identities = 48/178 (26%), Positives = 75/178 (42%), Gaps = 13/178 (7%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
V +C G P+P I W + + G L+I + ED G YTC A+N
Sbjct: 915 VALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATN 973
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G+ + + L V+ L G+ + N+ V V +C GNP P +
Sbjct: 974 AAGETQQHIQLHVHEPPSLEDAGKML---------NETVLVSNPVQLECKAAGNPVPVIT 1024
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KD +++ S +T + + I++I+ I D GIY+ N G E L+V
Sbjct: 1025 WYKDNRLLSGSTSMTFLNRGQ---IIDIESAQISDAGIYKCVAINSAGATELFYSLQV 1079
Score = 68.5 bits (160), Expect = 2e-11
Identities = 47/179 (26%), Positives = 78/179 (43%), Gaps = 13/179 (7%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
++ EC+ G P P I W+ + I + ++ Y D L I + D TYTC +N
Sbjct: 636 IKLECETRGLPMPAITWYKDGQPIMSSS--QALYIDKGQYLHIPRAQVSDSATYTCHVAN 693
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G A+ + + VY + +A P NK V ++T +C GNPSP +
Sbjct: 694 VAGTAEKSFHVDVYVPPMIEG---NLAT-----PLNKQVVIAHSLTLECKAAGNPSPILT 745
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVI 187
W KDG + + I ++ + + I+ E+ D G Y + G E ++V+
Sbjct: 746 WLKDGVPVKANDNIRIEAGGKKLEIMSAQEI---DRGQYICVATSVAGEKEIKYEVDVL 801
Score = 66.5 bits (155), Expect = 7e-11
Identities = 50/178 (28%), Positives = 71/178 (39%), Gaps = 13/178 (7%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
V ECQV G P PDI WF + + D D L +K D+G Y C SN
Sbjct: 542 VALECQVKGTPFPDIHWFKDGKPL-FLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSN 600
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
GK + L +Y + T + N +++ +C +G P P +
Sbjct: 601 AAGKQAKDIKLTIYIPPSIKGGN---VTTDISVLINSLIK------LECETRGLPMPAIT 651
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KDG I S++ +K + L I + D Y V N G AE S ++V
Sbjct: 652 WYKDGQPIMSSSQALYIDKGQ---YLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDV 706
Score = 63.7 bits (148), Expect = 5e-10
Identities = 52/179 (29%), Positives = 71/179 (39%), Gaps = 13/179 (7%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
+EF C G P P I+W H + S +DGT L I VT D G Y C A N
Sbjct: 355 IEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGTL-LVIASVTPYDNGEYICVAVN 413
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G + L V H + Q+ N V + C V+G PSP
Sbjct: 414 EAGTTERKYNLKV-HVPPVIKDKEQVT--------NVSVLLNQLTNLFCEVEGTPSPIIM 464
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVI 187
W KD +T S+ I RIL++ + ED G Y N G ++ ++V+
Sbjct: 465 WYKDNVQVTESSTIQTVNNG---RILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVL 520
Score = 63.3 bits (147), Expect = 6e-10
Identities = 46/178 (25%), Positives = 78/178 (43%), Gaps = 14/178 (7%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
+E +C VTG+P P I W +++ + F+ + +L I Q + G Y C A+N
Sbjct: 823 LELDCHVTGSPPPTIMWLKDGQLVDERDGFKILLNG--RKLVIAQAQVSNTGLYRCMAAN 880
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G K + V+ + S G +VV + + V +C G P+P +
Sbjct: 881 TAGDHKEEFEVTVHVPPTIKSSGLS----------ERVVVKYKPVALQCIANGIPNPSIT 930
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KD + +A+ +K + R+L+I + +ED G Y N G + +L V
Sbjct: 931 WLKDDQPVN-TAQGNLKIQSS-GRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHV 986
Score = 62.1 bits (144), Expect = 1e-09
Identities = 52/182 (28%), Positives = 71/182 (39%), Gaps = 12/182 (6%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G V+ C G P P I W + + S DGT L I Q T D G YTC
Sbjct: 256 GQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGT--LSIDQATPSDAGIYTCV 313
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A+N G ++ L V + + P + T +V + + F C KG P P
Sbjct: 314 ATNIAGTDETEITLHVQEPPTVED----LEPPYNTTFQERVANQ--RIEFPCPAKGTPKP 367
Query: 126 WASWDKDGSIIT-PSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
W +G +T I++ E +L I V+ D G Y NE G E L
Sbjct: 368 TIKWLHNGRELTGREPGISILEDG---TLLVIASVTPYDNGEYICVAVNEAGTTERKYNL 424
Query: 185 EV 186
+V
Sbjct: 425 KV 426
Score = 60.5 bits (140), Expect = 5e-09
Identities = 47/181 (25%), Positives = 67/181 (37%), Gaps = 16/181 (8%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+ V C+V P P I W ++I + + G+ +KI + D G Y C
Sbjct: 165 GEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGS--MKITETRTSDSGMYLCV 222
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A N G L V+ + P P + V+ G+ V C +G P P
Sbjct: 223 AINIAGNVTQAVKLNVH-----------VPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLP 271
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
+W K GS + V + L ID+ + D GIY N G E L
Sbjct: 272 VITWSKGGSTMLVDGEHHVSNPD---GTLSIDQATPSDAGIYTCVATNIAGTDETEITLH 328
Query: 186 V 186
V
Sbjct: 329 V 329
Score = 58.0 bits (134), Expect = 2e-08
Identities = 44/175 (25%), Positives = 75/175 (42%), Gaps = 15/175 (8%)
Query: 13 CQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLGK 72
C+V G P P I W+ + + + ++ ++G LK+ + T ED G Y+C+A N G
Sbjct: 453 CEVEGTPSPIIMWYKDNVQVTESSTIQT-VNNGRI-LKLFRATPEDAGRYSCKAINIAGT 510
Query: 73 AKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKD 132
++ Y + P + F P V +V +C VKG P P W KD
Sbjct: 511 SQK------YFNIDVLVPPTIIGTNF---PNEVSVVLNRDVALECQVKGTPFPDIHWFKD 561
Query: 133 GS-IITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
G + + + ++ + +L + D G Y+ TV N G+ +L +
Sbjct: 562 GKPLFLGDPNVELLDRGQ---VLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTI 613
Score = 55.6 bits (128), Expect = 1e-07
Identities = 47/153 (30%), Positives = 62/153 (40%), Gaps = 15/153 (9%)
Query: 49 LKIKQVTAEDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVE 108
L I++V +D G YTC ASN G +VV H G+Q+ T
Sbjct: 16 LHIERVQLQDGGEYTCVASNVAGTNNKTTSVVV-HVLPTIQHGQQILSTI---------- 64
Query: 109 EGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYR 168
EG VT C GNP P W K G +I+ S + K L + E+ G Y
Sbjct: 65 EGIPVTLPCKASGNPKPSVIWSKKGELISTS---SAKFSAGADGSLYVVSPGGEESGEYV 121
Query: 169 ITVENELGRAEASARLEVITRSGKFYGGLRAYS 201
T N G A+ +L V R + +G R S
Sbjct: 122 CTATNTAGYAKRKVQLTVYVRP-RVFGDQRGLS 153
Score = 50.8 bits (116), Expect = 4e-06
Identities = 45/179 (25%), Positives = 68/179 (37%), Gaps = 17/179 (9%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
V+ EC+ GNP P I W+ ++ ++ + + I+ D G Y C A N
Sbjct: 1009 VQLECKAAGNPVPVITWYKDNRLLSGSTSM--TFLNRGQIIDIESAQISDAGIYKCVAIN 1066
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G + L V+ +S +A V V +C +G P+P +
Sbjct: 1067 SAGATELFYSLQVHVAPSISGSNNMVA-----------VVVNNPVRLECEARGIPAPSLT 1115
Query: 129 WDKDGSIITP-SARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KDGS ++ S + V RIL + I D G Y N G + L V
Sbjct: 1116 WLKDGSPVSSFSNGLQVLSGG---RILALTSAQISDTGRYTCVAVNAAGEKQRDIDLRV 1171
Score = 50.0 bits (114), Expect = 6e-06
Identities = 39/168 (23%), Positives = 61/168 (36%), Gaps = 15/168 (8%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
V EC+ G P P + W + ++ G L + D G YTC A N
Sbjct: 1100 VRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRI-LALTSAQISDTGRYTCVAVN 1158
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G+ + + L VY + P N V + V C P P +
Sbjct: 1159 AAGEKQRDIDLRVY-----------VPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLT 1207
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG 176
W KDG + +++ E +L+I++ ++D G Y N G
Sbjct: 1208 WLKDGHPLLKKPGLSISENRS---VLKIEDAQVQDTGRYTCEATNVAG 1252
Score = 48.4 bits (110), Expect = 2e-05
Identities = 39/171 (22%), Positives = 68/171 (39%), Gaps = 18/171 (10%)
Query: 8 TVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEAS 67
++ EC+ GNP P + W ++ A+ + G +L+I D G Y C A+
Sbjct: 729 SLTLECKAAGNPSPILTWLKDGVPVK--ANDNIRIEAGGKKLEIMSAQEIDRGQYICVAT 786
Query: 68 NCLGKAKSNACLVVYHTRRLSSPGRQMA--PTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
+ G+ + + Y L P + +++ N ++E C V G+P P
Sbjct: 787 SVAGEKE-----IKYEVDVLVPPAIEGGDETSYFIVMVNNLLE------LDCHVTGSPPP 835
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG 176
W KDG ++ + R L I + + + G+YR N G
Sbjct: 836 TIMWLKDGQLVDERDGFKILLNG---RKLVIAQAQVSNTGLYRCMAANTAG 883
>AL834247-1|CAD38923.2| 1391|Homo sapiens hypothetical protein
protein.
Length = 1391
Score = 73.7 bits (173), Expect = 5e-13
Identities = 59/212 (27%), Positives = 88/212 (41%), Gaps = 24/212 (11%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVI--RDCADFESSYDDGTARLKIKQVTAEDEGTY 62
+G V F C++ G P P + WF + I R+ DGT L I+ T++D+G Y
Sbjct: 1029 EGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNERCKMRREGDGTCSLHIESTTSDDDGNY 1088
Query: 63 TCEASNCLGKAKSNACLVVYHT---RRLSSPG-------------------RQMAPTFYT 100
T A+N G+ + L+V RL+S G R P F
Sbjct: 1089 TIMAANPQGRISCSGHLMVQSLPIRSRLTSAGQSHRGRSRVQERDKEPLQERFFRPHFLQ 1148
Query: 101 YPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVS 160
P + V EG C V G P P +W +G + P A + +E + L ID ++
Sbjct: 1149 APGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDAPHKMLVRETGVHSLLIDPLT 1208
Query: 161 IEDVGIYRITVENELGRAEASARLEVITRSGK 192
D G Y+ N+ G+ S L V+ + K
Sbjct: 1209 QRDAGTYKCIATNKTGQNSFSLELSVVAKEVK 1240
Score = 69.7 bits (163), Expect = 7e-12
Identities = 53/188 (28%), Positives = 80/188 (42%), Gaps = 8/188 (4%)
Query: 1 MLSCDGDTVEFECQVTGNPDPDIRWFHYAE-VIRDCADFESSYDDGTARLKIKQVTAEDE 59
M++ +G +C+V+G P P++ W + V+ D + G L I +T D
Sbjct: 1153 MVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDAPHKMLVRETGVHSLLIDPLTQRDA 1212
Query: 60 GTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAV 119
GTY C A+N G+ + L V + + AP N V EG V +C V
Sbjct: 1213 GTYKCIATNKTGQNSFSLELSVV------AKEVKKAPVILEKLQNCGVPEGHPVRLECRV 1266
Query: 120 KGNPSPWASWDKDGSII-TPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRA 178
G P P W KD I RI++ + L I D G Y ++ +NE G
Sbjct: 1267 IGMPPPVFYWKKDNETIPCTRERISMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEAGIV 1326
Query: 179 EASARLEV 186
+ARL++
Sbjct: 1327 SCTARLDI 1334
Score = 58.8 bits (136), Expect = 1e-08
Identities = 43/134 (32%), Positives = 60/134 (44%), Gaps = 9/134 (6%)
Query: 95 APTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSII--TPSARITVK------E 146
AP F N EG+ V F+C VKG PSP W ++G++I +P RI K E
Sbjct: 505 APVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAE 564
Query: 147 KEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVITRSGKFYGGLRAYSASPRK 206
EEI ++ I EV ED G + T N+ G + A+L V G + S
Sbjct: 565 PEEICTLV-IAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDLSNNGSLHSANSTTN 623
Query: 207 CLSYRRRPSTPRQD 220
+ +PS P +
Sbjct: 624 LAAIEPQPSPPHSE 637
Score = 56.0 bits (129), Expect = 1e-07
Identities = 34/95 (35%), Positives = 44/95 (46%), Gaps = 8/95 (8%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADF--------ESSYDDGTARLKIKQVTA 56
+G V FEC+V G P P + W+ +I D DF + + L I +V A
Sbjct: 519 EGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEPEEICTLVIAEVFA 578
Query: 57 EDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPG 91
ED G +TC ASN G S A L V LS+ G
Sbjct: 579 EDSGCFTCTASNKYGTVSSIAQLHVRGNEDLSNNG 613
Score = 48.4 bits (110), Expect = 2e-05
Identities = 32/97 (32%), Positives = 45/97 (46%), Gaps = 1/97 (1%)
Query: 91 GRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITP-SARITVKEKEE 149
G+ +AP F + V EG VTF C + G P P W KDG I+ + R ++ + +
Sbjct: 1011 GKCIAPIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNERCKMRREGD 1070
Query: 150 IMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
L I+ + +D G Y I N GR S L V
Sbjct: 1071 GTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMV 1107
Score = 47.2 bits (107), Expect = 4e-05
Identities = 24/87 (27%), Positives = 38/87 (43%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G V+ +C V G P P +RW+ + + + D L I + ED G Y+C
Sbjct: 353 EGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHSLTIAEAFEEDTGRYSC 412
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPG 91
ASN G ++A + + S G
Sbjct: 413 FASNIYGTDSTSAEIYIEGVSSSDSEG 439
Score = 38.7 bits (86), Expect = 0.016
Identities = 27/80 (33%), Positives = 33/80 (41%), Gaps = 2/80 (2%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDD--GTARLKIKQVTAEDEGTY 62
+G V EC+V G P P W E I + S + D G A L I+ D G Y
Sbjct: 1256 EGHPVRLECRVIGMPPPVFYWKKDNETIPCTRERISMHQDTTGYACLLIQPAKKSDAGWY 1315
Query: 63 TCEASNCLGKAKSNACLVVY 82
T A N G A L +Y
Sbjct: 1316 TLSAKNEAGIVSCTARLDIY 1335
Score = 35.9 bits (79), Expect = 0.11
Identities = 26/91 (28%), Positives = 35/91 (38%), Gaps = 1/91 (1%)
Query: 96 PTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILE 155
P F ++ V EG V C V G P P W +G + S I + + + L
Sbjct: 340 PRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGN-LHSLT 398
Query: 156 IDEVSIEDVGIYRITVENELGRAEASARLEV 186
I E ED G Y N G SA + +
Sbjct: 399 IAEAFEEDTGRYSCFASNIYGTDSTSAEIYI 429
>AL832379-1|CAD91155.1| 1045|Homo sapiens hypothetical protein
protein.
Length = 1045
Score = 73.7 bits (173), Expect = 5e-13
Identities = 58/212 (27%), Positives = 87/212 (41%), Gaps = 24/212 (11%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADF--ESSYDDGTARLKIKQVTAEDEGTY 62
+G V F C++ G P P + WF + I + DGT L I+ T++D+G Y
Sbjct: 683 EGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGTCSLHIESTTSDDDGNY 742
Query: 63 TCEASNCLGKAKSNACLVVYHT---RRLSSPG-------------------RQMAPTFYT 100
T A+N G+ + L+V RL+S G R P F
Sbjct: 743 TIMAANPQGRISCSGHLMVQSLPIRSRLTSAGQSHRGRSRVQERDKEPLQERFFRPHFLQ 802
Query: 101 YPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVS 160
P + V EG C V G P P +W +G + P A + +E + L ID ++
Sbjct: 803 TPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLLIDPLT 862
Query: 161 IEDVGIYRITVENELGRAEASARLEVITRSGK 192
D G Y+ N+ G+ S L V+ + K
Sbjct: 863 QRDAGTYKCIATNKTGQNSFSLELSVVAKEVK 894
Score = 70.5 bits (165), Expect = 4e-12
Identities = 53/188 (28%), Positives = 81/188 (43%), Gaps = 8/188 (4%)
Query: 1 MLSCDGDTVEFECQVTGNPDPDIRWFHYAE-VIRDCADFESSYDDGTARLKIKQVTAEDE 59
M++ +G +C+V+G P P++ W + V+ D + + G L I +T D
Sbjct: 807 MVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLLIDPLTQRDA 866
Query: 60 GTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAV 119
GTY C A+N G+ + L V + + AP N V EG V +C V
Sbjct: 867 GTYKCIATNKTGQNSFSLELSVV------AKEVKKAPVILEKLQNCGVPEGHPVRLECRV 920
Query: 120 KGNPSPWASWDKDGSII-TPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRA 178
G P P W KD I RI++ + L I D G Y ++ +NE G
Sbjct: 921 IGMPPPVFYWKKDNETIPCTRERISMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEAGIV 980
Query: 179 EASARLEV 186
+ARL++
Sbjct: 981 SCTARLDI 988
Score = 58.8 bits (136), Expect = 1e-08
Identities = 43/134 (32%), Positives = 60/134 (44%), Gaps = 9/134 (6%)
Query: 95 APTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSII--TPSARITVK------E 146
AP F N EG+ V F+C VKG PSP W ++G++I +P RI K E
Sbjct: 159 APVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAE 218
Query: 147 KEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVITRSGKFYGGLRAYSASPRK 206
EEI ++ I EV ED G + T N+ G + A+L V G + S
Sbjct: 219 PEEICTLV-IAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDLSNNGSLHSANSTTN 277
Query: 207 CLSYRRRPSTPRQD 220
+ +PS P +
Sbjct: 278 LAAIEPQPSPPHSE 291
Score = 56.0 bits (129), Expect = 1e-07
Identities = 34/95 (35%), Positives = 44/95 (46%), Gaps = 8/95 (8%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADF--------ESSYDDGTARLKIKQVTA 56
+G V FEC+V G P P + W+ +I D DF + + L I +V A
Sbjct: 173 EGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEPEEICTLVIAEVFA 232
Query: 57 EDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPG 91
ED G +TC ASN G S A L V LS+ G
Sbjct: 233 EDSGCFTCTASNKYGTVSSIAQLHVRGNEDLSNNG 267
Score = 46.4 bits (105), Expect = 8e-05
Identities = 31/97 (31%), Positives = 44/97 (45%), Gaps = 1/97 (1%)
Query: 91 GRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITP-SARITVKEKEE 149
G+ +AP F + V EG VTF C + G P P W KDG I+ + ++ + +
Sbjct: 665 GKCIAPIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGD 724
Query: 150 IMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
L I+ + +D G Y I N GR S L V
Sbjct: 725 GTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMV 761
Score = 38.7 bits (86), Expect = 0.016
Identities = 27/80 (33%), Positives = 33/80 (41%), Gaps = 2/80 (2%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDD--GTARLKIKQVTAEDEGTY 62
+G V EC+V G P P W E I + S + D G A L I+ D G Y
Sbjct: 910 EGHPVRLECRVIGMPPPVFYWKKDNETIPCTRERISMHQDTTGYACLLIQPAKKSDAGWY 969
Query: 63 TCEASNCLGKAKSNACLVVY 82
T A N G A L +Y
Sbjct: 970 TLSAKNEAGIVSCTARLDIY 989
>AL832002-1|CAD89906.1| 1320|Homo sapiens hypothetical protein
protein.
Length = 1320
Score = 73.7 bits (173), Expect = 5e-13
Identities = 58/212 (27%), Positives = 87/212 (41%), Gaps = 24/212 (11%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADF--ESSYDDGTARLKIKQVTAEDEGTY 62
+G V F C++ G P P + WF + I + DGT L I+ T++D+G Y
Sbjct: 958 EGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGTCSLHIESTTSDDDGNY 1017
Query: 63 TCEASNCLGKAKSNACLVVYHT---RRLSSPG-------------------RQMAPTFYT 100
T A+N G+ + L+V RL+S G R P F
Sbjct: 1018 TIMAANPQGRISCSGHLMVQSLPIRSRLTSAGQSHRGRSRVQERDKEPLQERFFRPHFLQ 1077
Query: 101 YPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVS 160
P + V EG C V G P P +W +G + P A + +E + L ID ++
Sbjct: 1078 APGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLLIDPLT 1137
Query: 161 IEDVGIYRITVENELGRAEASARLEVITRSGK 192
D G Y+ N+ G+ S L V+ + K
Sbjct: 1138 QRDAGTYKCIATNKTGQNSFSLELSVVAKEVK 1169
Score = 70.5 bits (165), Expect = 4e-12
Identities = 53/188 (28%), Positives = 81/188 (43%), Gaps = 8/188 (4%)
Query: 1 MLSCDGDTVEFECQVTGNPDPDIRWFHYAE-VIRDCADFESSYDDGTARLKIKQVTAEDE 59
M++ +G +C+V+G P P++ W + V+ D + + G L I +T D
Sbjct: 1082 MVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLLIDPLTQRDA 1141
Query: 60 GTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAV 119
GTY C A+N G+ + L V + + AP N V EG V +C V
Sbjct: 1142 GTYKCIATNKTGQNSFSLELSVV------AKEVKKAPVILEKLQNCGVPEGHPVRLECRV 1195
Query: 120 KGNPSPWASWDKDGSII-TPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRA 178
G P P W KD I RI++ + L I D G Y ++ +NE G
Sbjct: 1196 IGMPPPVFYWKKDNETIPCTRERISMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEAGIV 1255
Query: 179 EASARLEV 186
+ARL++
Sbjct: 1256 SCTARLDI 1263
Score = 56.8 bits (131), Expect = 6e-08
Identities = 42/134 (31%), Positives = 60/134 (44%), Gaps = 9/134 (6%)
Query: 95 APTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSII--TPSARITVK------E 146
AP F N EG+ V F+C VKG PSP W ++G++I +P RI+ K E
Sbjct: 434 APVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRISQKKPRSMAE 493
Query: 147 KEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVITRSGKFYGGLRAYSASPRK 206
EEI ++ I EV E G + T N+ G + A+L V G + S
Sbjct: 494 PEEICTLV-IAEVFAEGSGCFTCTASNKYGTVSSIAQLHVRGNEDLSNNGSLHSANSTTN 552
Query: 207 CLSYRRRPSTPRQD 220
+ +PS P +
Sbjct: 553 LAAIEPQPSPPHSE 566
Score = 54.4 bits (125), Expect = 3e-07
Identities = 34/95 (35%), Positives = 43/95 (45%), Gaps = 8/95 (8%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSY--------DDGTARLKIKQVTA 56
+G V FEC+V G P P + W+ +I D DF S + L I +V A
Sbjct: 448 EGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRISQKKPRSMAEPEEICTLVIAEVFA 507
Query: 57 EDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPG 91
E G +TC ASN G S A L V LS+ G
Sbjct: 508 EGSGCFTCTASNKYGTVSSIAQLHVRGNEDLSNNG 542
Score = 47.2 bits (107), Expect = 4e-05
Identities = 24/87 (27%), Positives = 38/87 (43%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G V+ +C V G P P +RW+ + + + D L I + ED G Y+C
Sbjct: 282 EGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHSLTIAEAFEEDTGRYSC 341
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPG 91
ASN G ++A + + S G
Sbjct: 342 FASNIYGTDSTSAEIYIEGVSSSDSEG 368
Score = 46.4 bits (105), Expect = 8e-05
Identities = 31/97 (31%), Positives = 44/97 (45%), Gaps = 1/97 (1%)
Query: 91 GRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITP-SARITVKEKEE 149
G+ +AP F + V EG VTF C + G P P W KDG I+ + ++ + +
Sbjct: 940 GKCIAPIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGD 999
Query: 150 IMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
L I+ + +D G Y I N GR S L V
Sbjct: 1000 GTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMV 1036
Score = 38.7 bits (86), Expect = 0.016
Identities = 27/80 (33%), Positives = 33/80 (41%), Gaps = 2/80 (2%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDD--GTARLKIKQVTAEDEGTY 62
+G V EC+V G P P W E I + S + D G A L I+ D G Y
Sbjct: 1185 EGHPVRLECRVIGMPPPVFYWKKDNETIPCTRERISMHQDTTGYACLLIQPAKKSDAGWY 1244
Query: 63 TCEASNCLGKAKSNACLVVY 82
T A N G A L +Y
Sbjct: 1245 TLSAKNEAGIVSCTARLDIY 1264
Score = 35.9 bits (79), Expect = 0.11
Identities = 26/91 (28%), Positives = 35/91 (38%), Gaps = 1/91 (1%)
Query: 96 PTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILE 155
P F ++ V EG V C V G P P W +G + S I + + + L
Sbjct: 269 PRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGN-LHSLT 327
Query: 156 IDEVSIEDVGIYRITVENELGRAEASARLEV 186
I E ED G Y N G SA + +
Sbjct: 328 IAEAFEEDTGRYSCFASNIYGTDSTSAEIYI 358
>AL512429-2|CAH73748.1| 1320|Homo sapiens sarcomeric protein
myopalladin, 145 kDa (MYOP) protein.
Length = 1320
Score = 73.7 bits (173), Expect = 5e-13
Identities = 58/212 (27%), Positives = 87/212 (41%), Gaps = 24/212 (11%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADF--ESSYDDGTARLKIKQVTAEDEGTY 62
+G V F C++ G P P + WF + I + DGT L I+ T++D+G Y
Sbjct: 958 EGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGTCSLHIESTTSDDDGNY 1017
Query: 63 TCEASNCLGKAKSNACLVVYHT---RRLSSPG-------------------RQMAPTFYT 100
T A+N G+ + L+V RL+S G R P F
Sbjct: 1018 TIMAANPQGRISCSGHLMVQSLPIRSRLTSAGQSHRGRSRVQERDKEPLQERFFRPHFLQ 1077
Query: 101 YPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVS 160
P + V EG C V G P P +W +G + P A + +E + L ID ++
Sbjct: 1078 APGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLLIDPLT 1137
Query: 161 IEDVGIYRITVENELGRAEASARLEVITRSGK 192
D G Y+ N+ G+ S L V+ + K
Sbjct: 1138 QRDAGTYKCIATNKTGQNSFSLELSVVAKEVK 1169
Score = 70.5 bits (165), Expect = 4e-12
Identities = 53/188 (28%), Positives = 81/188 (43%), Gaps = 8/188 (4%)
Query: 1 MLSCDGDTVEFECQVTGNPDPDIRWFHYAE-VIRDCADFESSYDDGTARLKIKQVTAEDE 59
M++ +G +C+V+G P P++ W + V+ D + + G L I +T D
Sbjct: 1082 MVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLLIDPLTQRDA 1141
Query: 60 GTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAV 119
GTY C A+N G+ + L V + + AP N V EG V +C V
Sbjct: 1142 GTYKCIATNKTGQNSFSLELSVV------AKEVKKAPVILEKLQNCGVPEGHPVRLECRV 1195
Query: 120 KGNPSPWASWDKDGSII-TPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRA 178
G P P W KD I RI++ + L I D G Y ++ +NE G
Sbjct: 1196 IGMPPPVFYWKKDNETIPCTRERISMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEAGIV 1255
Query: 179 EASARLEV 186
+ARL++
Sbjct: 1256 SCTARLDI 1263
Score = 58.8 bits (136), Expect = 1e-08
Identities = 43/134 (32%), Positives = 60/134 (44%), Gaps = 9/134 (6%)
Query: 95 APTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSII--TPSARITVK------E 146
AP F N EG+ V F+C VKG PSP W ++G++I +P RI K E
Sbjct: 434 APVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAE 493
Query: 147 KEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVITRSGKFYGGLRAYSASPRK 206
EEI ++ I EV ED G + T N+ G + A+L V G + S
Sbjct: 494 PEEICTLV-IAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDLSNNGSLHSANSTTN 552
Query: 207 CLSYRRRPSTPRQD 220
+ +PS P +
Sbjct: 553 LAAIEPQPSPPHSE 566
Score = 56.0 bits (129), Expect = 1e-07
Identities = 34/95 (35%), Positives = 44/95 (46%), Gaps = 8/95 (8%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADF--------ESSYDDGTARLKIKQVTA 56
+G V FEC+V G P P + W+ +I D DF + + L I +V A
Sbjct: 448 EGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEPEEICTLVIAEVFA 507
Query: 57 EDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPG 91
ED G +TC ASN G S A L V LS+ G
Sbjct: 508 EDSGCFTCTASNKYGTVSSIAQLHVRGNEDLSNNG 542
Score = 47.2 bits (107), Expect = 4e-05
Identities = 24/87 (27%), Positives = 38/87 (43%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G V+ +C V G P P +RW+ + + + D L I + ED G Y+C
Sbjct: 282 EGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHSLTIAEAFEEDTGRYSC 341
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPG 91
ASN G ++A + + S G
Sbjct: 342 FASNIYGTDSTSAEIYIEGVSSSDSEG 368
Score = 46.4 bits (105), Expect = 8e-05
Identities = 31/97 (31%), Positives = 44/97 (45%), Gaps = 1/97 (1%)
Query: 91 GRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITP-SARITVKEKEE 149
G+ +AP F + V EG VTF C + G P P W KDG I+ + ++ + +
Sbjct: 940 GKCIAPIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGD 999
Query: 150 IMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
L I+ + +D G Y I N GR S L V
Sbjct: 1000 GTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMV 1036
Score = 38.7 bits (86), Expect = 0.016
Identities = 27/80 (33%), Positives = 33/80 (41%), Gaps = 2/80 (2%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDD--GTARLKIKQVTAEDEGTY 62
+G V EC+V G P P W E I + S + D G A L I+ D G Y
Sbjct: 1185 EGHPVRLECRVIGMPPPVFYWKKDNETIPCTRERISMHQDTTGYACLLIQPAKKSDAGWY 1244
Query: 63 TCEASNCLGKAKSNACLVVY 82
T A N G A L +Y
Sbjct: 1245 TLSAKNEAGIVSCTARLDIY 1264
Score = 35.9 bits (79), Expect = 0.11
Identities = 26/91 (28%), Positives = 35/91 (38%), Gaps = 1/91 (1%)
Query: 96 PTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILE 155
P F ++ V EG V C V G P P W +G + S I + + + L
Sbjct: 269 PRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGN-LHSLT 327
Query: 156 IDEVSIEDVGIYRITVENELGRAEASARLEV 186
I E ED G Y N G SA + +
Sbjct: 328 IAEAFEEDTGRYSCFASNIYGTDSTSAEIYI 358
>AL512429-1|CAH73747.1| 1045|Homo sapiens sarcomeric protein
myopalladin, 145 kDa (MYOP) protein.
Length = 1045
Score = 73.7 bits (173), Expect = 5e-13
Identities = 58/212 (27%), Positives = 87/212 (41%), Gaps = 24/212 (11%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADF--ESSYDDGTARLKIKQVTAEDEGTY 62
+G V F C++ G P P + WF + I + DGT L I+ T++D+G Y
Sbjct: 683 EGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGTCSLHIESTTSDDDGNY 742
Query: 63 TCEASNCLGKAKSNACLVVYHT---RRLSSPG-------------------RQMAPTFYT 100
T A+N G+ + L+V RL+S G R P F
Sbjct: 743 TIMAANPQGRISCSGHLMVQSLPIRSRLTSAGQSHRGRSRVQERDKEPLQERFFRPHFLQ 802
Query: 101 YPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVS 160
P + V EG C V G P P +W +G + P A + +E + L ID ++
Sbjct: 803 APGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLLIDPLT 862
Query: 161 IEDVGIYRITVENELGRAEASARLEVITRSGK 192
D G Y+ N+ G+ S L V+ + K
Sbjct: 863 QRDAGTYKCIATNKTGQNSFSLELSVVAKEVK 894
Score = 70.5 bits (165), Expect = 4e-12
Identities = 53/188 (28%), Positives = 81/188 (43%), Gaps = 8/188 (4%)
Query: 1 MLSCDGDTVEFECQVTGNPDPDIRWFHYAE-VIRDCADFESSYDDGTARLKIKQVTAEDE 59
M++ +G +C+V+G P P++ W + V+ D + + G L I +T D
Sbjct: 807 MVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLLIDPLTQRDA 866
Query: 60 GTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAV 119
GTY C A+N G+ + L V + + AP N V EG V +C V
Sbjct: 867 GTYKCIATNKTGQNSFSLELSVV------AKEVKKAPVILEKLQNCGVPEGHPVRLECRV 920
Query: 120 KGNPSPWASWDKDGSII-TPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRA 178
G P P W KD I RI++ + L I D G Y ++ +NE G
Sbjct: 921 IGMPPPVFYWKKDNETIPCTRERISMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEAGIV 980
Query: 179 EASARLEV 186
+ARL++
Sbjct: 981 SCTARLDI 988
Score = 58.8 bits (136), Expect = 1e-08
Identities = 43/134 (32%), Positives = 60/134 (44%), Gaps = 9/134 (6%)
Query: 95 APTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSII--TPSARITVK------E 146
AP F N EG+ V F+C VKG PSP W ++G++I +P RI K E
Sbjct: 159 APVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAE 218
Query: 147 KEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVITRSGKFYGGLRAYSASPRK 206
EEI ++ I EV ED G + T N+ G + A+L V G + S
Sbjct: 219 PEEICTLV-IAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDLSNNGSLHSANSTTN 277
Query: 207 CLSYRRRPSTPRQD 220
+ +PS P +
Sbjct: 278 LAAIEPQPSPPHSE 291
Score = 56.0 bits (129), Expect = 1e-07
Identities = 34/95 (35%), Positives = 44/95 (46%), Gaps = 8/95 (8%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADF--------ESSYDDGTARLKIKQVTA 56
+G V FEC+V G P P + W+ +I D DF + + L I +V A
Sbjct: 173 EGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEPEEICTLVIAEVFA 232
Query: 57 EDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPG 91
ED G +TC ASN G S A L V LS+ G
Sbjct: 233 EDSGCFTCTASNKYGTVSSIAQLHVRGNEDLSNNG 267
Score = 46.4 bits (105), Expect = 8e-05
Identities = 31/97 (31%), Positives = 44/97 (45%), Gaps = 1/97 (1%)
Query: 91 GRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITP-SARITVKEKEE 149
G+ +AP F + V EG VTF C + G P P W KDG I+ + ++ + +
Sbjct: 665 GKCIAPIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGD 724
Query: 150 IMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
L I+ + +D G Y I N GR S L V
Sbjct: 725 GTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMV 761
Score = 38.7 bits (86), Expect = 0.016
Identities = 27/80 (33%), Positives = 33/80 (41%), Gaps = 2/80 (2%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDD--GTARLKIKQVTAEDEGTY 62
+G V EC+V G P P W E I + S + D G A L I+ D G Y
Sbjct: 910 EGHPVRLECRVIGMPPPVFYWKKDNETIPCTRERISMHQDTTGYACLLIQPAKKSDAGWY 969
Query: 63 TCEASNCLGKAKSNACLVVY 82
T A N G A L +Y
Sbjct: 970 TLSAKNEAGIVSCTARLDIY 989
>AF328296-1|AAK50625.1| 1320|Homo sapiens myopalladin protein.
Length = 1320
Score = 73.7 bits (173), Expect = 5e-13
Identities = 58/212 (27%), Positives = 87/212 (41%), Gaps = 24/212 (11%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADF--ESSYDDGTARLKIKQVTAEDEGTY 62
+G V F C++ G P P + WF + I + DGT L I+ T++D+G Y
Sbjct: 958 EGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGTCSLHIESTTSDDDGNY 1017
Query: 63 TCEASNCLGKAKSNACLVVYHT---RRLSSPG-------------------RQMAPTFYT 100
T A+N G+ + L+V RL+S G R P F
Sbjct: 1018 TIMAANPQGRISCSGHLMVQSLPIRSRLTSAGQSHRGRSRVQERDKEPLQERFFRPHFLQ 1077
Query: 101 YPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVS 160
P + V EG C V G P P +W +G + P A + +E + L ID ++
Sbjct: 1078 APGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLLIDPLT 1137
Query: 161 IEDVGIYRITVENELGRAEASARLEVITRSGK 192
D G Y+ N+ G+ S L V+ + K
Sbjct: 1138 QRDAGTYKCIATNKTGQNSFSLELSVVAKEVK 1169
Score = 70.5 bits (165), Expect = 4e-12
Identities = 53/188 (28%), Positives = 81/188 (43%), Gaps = 8/188 (4%)
Query: 1 MLSCDGDTVEFECQVTGNPDPDIRWFHYAE-VIRDCADFESSYDDGTARLKIKQVTAEDE 59
M++ +G +C+V+G P P++ W + V+ D + + G L I +T D
Sbjct: 1082 MVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLLIDPLTQRDA 1141
Query: 60 GTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAV 119
GTY C A+N G+ + L V + + AP N V EG V +C V
Sbjct: 1142 GTYKCIATNKTGQNSFSLELSVV------AKEVKKAPVILEKLQNCGVPEGHPVRLECRV 1195
Query: 120 KGNPSPWASWDKDGSII-TPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRA 178
G P P W KD I RI++ + L I D G Y ++ +NE G
Sbjct: 1196 IGMPPPVFYWKKDNETIPCTRERISMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEAGIV 1255
Query: 179 EASARLEV 186
+ARL++
Sbjct: 1256 SCTARLDI 1263
Score = 58.8 bits (136), Expect = 1e-08
Identities = 43/134 (32%), Positives = 60/134 (44%), Gaps = 9/134 (6%)
Query: 95 APTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSII--TPSARITVK------E 146
AP F N EG+ V F+C VKG PSP W ++G++I +P RI K E
Sbjct: 434 APVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAE 493
Query: 147 KEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVITRSGKFYGGLRAYSASPRK 206
EEI ++ I EV ED G + T N+ G + A+L V G + S
Sbjct: 494 PEEICTLV-IAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDLSNNGSLHSANSTTN 552
Query: 207 CLSYRRRPSTPRQD 220
+ +PS P +
Sbjct: 553 LAAIEPQPSPPHSE 566
Score = 56.0 bits (129), Expect = 1e-07
Identities = 34/95 (35%), Positives = 44/95 (46%), Gaps = 8/95 (8%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADF--------ESSYDDGTARLKIKQVTA 56
+G V FEC+V G P P + W+ +I D DF + + L I +V A
Sbjct: 448 EGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEPEEICTLVIAEVFA 507
Query: 57 EDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPG 91
ED G +TC ASN G S A L V LS+ G
Sbjct: 508 EDSGCFTCTASNKYGTVSSIAQLHVRGNEDLSNNG 542
Score = 47.2 bits (107), Expect = 4e-05
Identities = 24/87 (27%), Positives = 38/87 (43%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G V+ +C V G P P +RW+ + + + D L I + ED G Y+C
Sbjct: 282 EGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHSLTIAEAFEEDTGRYSC 341
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPG 91
ASN G ++A + + S G
Sbjct: 342 FASNIYGTDSTSAEIYIEGVSSSDSEG 368
Score = 46.4 bits (105), Expect = 8e-05
Identities = 31/97 (31%), Positives = 44/97 (45%), Gaps = 1/97 (1%)
Query: 91 GRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITP-SARITVKEKEE 149
G+ +AP F + V EG VTF C + G P P W KDG I+ + ++ + +
Sbjct: 940 GKCIAPIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGD 999
Query: 150 IMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
L I+ + +D G Y I N GR S L V
Sbjct: 1000 GTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMV 1036
Score = 38.7 bits (86), Expect = 0.016
Identities = 27/80 (33%), Positives = 33/80 (41%), Gaps = 2/80 (2%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDD--GTARLKIKQVTAEDEGTY 62
+G V EC+V G P P W E I + S + D G A L I+ D G Y
Sbjct: 1185 EGHPVRLECRVIGMPPPVFYWKKDNETIPCTRERISMHQDTTGYACLLIQPAKKSDAGWY 1244
Query: 63 TCEASNCLGKAKSNACLVVY 82
T A N G A L +Y
Sbjct: 1245 TLSAKNEAGIVSCTARLDIY 1264
Score = 35.9 bits (79), Expect = 0.11
Identities = 26/91 (28%), Positives = 35/91 (38%), Gaps = 1/91 (1%)
Query: 96 PTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILE 155
P F ++ V EG V C V G P P W +G + S I + + + L
Sbjct: 269 PRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGN-LHSLT 327
Query: 156 IDEVSIEDVGIYRITVENELGRAEASARLEV 186
I E ED G Y N G SA + +
Sbjct: 328 IAEAFEEDTGRYSCFASNIYGTDSTSAEIYI 358
>AL834139-1|CAD38854.1| 1340|Homo sapiens hypothetical protein
protein.
Length = 1340
Score = 73.3 bits (172), Expect = 6e-13
Identities = 53/181 (29%), Positives = 76/181 (41%), Gaps = 18/181 (9%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G +++ +C V G+P PDI W +R + +G+ L I + +D G Y C
Sbjct: 1130 GGSIQLDCVVRGDPVPDIHWIKDGLPLRG-SHLRHQLQNGS--LTIHRTERDDAGRYQCL 1186
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A N +G AK LV+ Q AP F P + V G++V +C G P+P
Sbjct: 1187 AENEMGVAKKVVILVL-----------QSAPVFQVEPQDMTVRSGDDVALRCQATGEPTP 1235
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
W + G + S R+ L ++ V D G Y N LG A A A L
Sbjct: 1236 TIEWLQAGQPLRASRRLRTLPDGS----LWLENVETGDAGTYDCVAHNLLGSATARAFLV 1291
Query: 186 V 186
V
Sbjct: 1292 V 1292
Score = 71.3 bits (167), Expect = 2e-12
Identities = 46/182 (25%), Positives = 81/182 (44%), Gaps = 18/182 (9%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G C+ G+P+P+I W + + + G L +K + +D GTYTC
Sbjct: 948 EGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPSG--ELLVKNLEGQDAGTYTC 1005
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
A N +G+A+ L + + P F T P ++ + G+ + +CA +G+P+
Sbjct: 1006 TAENAVGRARRRVHLTIL-----------VLPVFTTLPGDRSLRLGDRLWLRCAARGSPT 1054
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
P W + +T +++ L+ VS ED G Y EN +GR +A + +
Sbjct: 1055 PRIGWTVNDRPVTEGV-----SEQDGGSTLQRAAVSREDSGTYVCWAENRVGRTQAVSFV 1109
Query: 185 EV 186
V
Sbjct: 1110 HV 1111
Score = 67.3 bits (157), Expect = 4e-11
Identities = 48/182 (26%), Positives = 75/182 (41%), Gaps = 19/182 (10%)
Query: 7 DTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEA 66
+ V C+ +G P P I W E + + G +L+I + ED G Y C A
Sbjct: 860 EEVLLPCEASGIPRPTITW--QKEGLNVATGVSTQVLPG-GQLRIAHASPEDAGNYLCIA 916
Query: 67 SNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPW 126
N G A LVV Q+ P + EG + C +G+P P
Sbjct: 917 KNSAGSAMGKTRLVV-----------QVPPVIENGLPDLSTTEGSHAFLPCKARGSPEPN 965
Query: 127 ASWDKDGSIIT-PSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
+WDKDG ++ + T++ E++ + + +D G Y T EN +GRA L
Sbjct: 966 ITWDKDGQPVSGAEGKFTIQPSGELL----VKNLEGQDAGTYTCTAENAVGRARRRVHLT 1021
Query: 186 VI 187
++
Sbjct: 1022 IL 1023
Score = 64.5 bits (150), Expect = 3e-10
Identities = 51/182 (28%), Positives = 77/182 (42%), Gaps = 13/182 (7%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVI-RDCADFESSYDDGTARLKIKQVTAEDEGTYT 63
+G V +C+ G P PD+ W + +D Y DG + L +K + A D G YT
Sbjct: 144 EGQEVRLDCEADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGS-LVLKGLWASDAGAYT 202
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
C A N G+ + V + G + T + P GE VT C V+G+P
Sbjct: 203 CVAHNPAGEDARLHTVNVLVPPTIKQ-GADGSGTLVSRP-------GELVTMVCPVRGSP 254
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
SW KDG + S R + +R I +V + D GI+ + G A+ +
Sbjct: 255 PIHVSWLKDGLPLPLSQRTLLHGSGHTLR---ISKVQLADAGIFTCVAASPAGVADRNFT 311
Query: 184 LE 185
L+
Sbjct: 312 LQ 313
Score = 60.9 bits (141), Expect = 3e-09
Identities = 46/183 (25%), Positives = 77/183 (42%), Gaps = 16/183 (8%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G +E C G P P+I W + + E++ T L+++ V D G YTC
Sbjct: 421 GAPMELLCDAQGTPQPNITWHKDGQAL---TRLENN-SRATRVLRVENVQVRDAGLYTCL 476
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A + G + + + V + P P F + G+ V +C+V+ P+P
Sbjct: 477 AESPAGAIEKSFRVRVQAPPNIVGP---RGPRFVVG-----LAPGQLV-LECSVEAEPAP 527
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
+W +DG ++ A E+ R L++ +S D G Y T N G + R+E
Sbjct: 528 KITWHRDGIVLQEDAHTQFPERG---RFLQLQALSTADSGDYSCTARNAAGSTSVAFRVE 584
Query: 186 VIT 188
+ T
Sbjct: 585 IHT 587
Score = 59.7 bits (138), Expect = 8e-09
Identities = 37/138 (26%), Positives = 61/138 (44%), Gaps = 14/138 (10%)
Query: 49 LKIKQVTAEDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVE 108
L+++ V A D GTY+C A + G+A+ + L V + G+ P +
Sbjct: 369 LQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVMEPPHIEDSGQ---------PTELSLT 419
Query: 109 EGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYR 168
G + C +G P P +W KDG +T ++ R+L ++ V + D G+Y
Sbjct: 420 PGAPMELLCDAQGTPQPNITWHKDGQALT-----RLENNSRATRVLRVENVQVRDAGLYT 474
Query: 169 ITVENELGRAEASARLEV 186
E+ G E S R+ V
Sbjct: 475 CLAESPAGAIEKSFRVRV 492
Score = 54.0 bits (124), Expect = 4e-07
Identities = 47/177 (26%), Positives = 67/177 (37%), Gaps = 18/177 (10%)
Query: 12 ECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLG 71
EC V P P I W V+++ D + + + L+++ ++ D G Y+C A N G
Sbjct: 518 ECSVEAEPAPKITWHRDGIVLQE--DAHTQFPERGRFLQLQALSTADSGDYSCTARNAAG 575
Query: 72 KAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDK 131
S A V HT PT + P V + C G P+P SW K
Sbjct: 576 ST-SVAFRVEIHT----------VPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSWRK 624
Query: 132 DGSIITP-SARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVI 187
D + P S R + + L I V +D G Y N G L V+
Sbjct: 625 DRVPLDPRSPRFEILPEGS----LRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRVL 677
Score = 53.6 bits (123), Expect = 5e-07
Identities = 40/133 (30%), Positives = 58/133 (43%), Gaps = 19/133 (14%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTA----RLKIKQVTAEDEGT 61
G + C V+G P P + W ++D ESS G RL++ ++ GT
Sbjct: 52 GSPLVLTCDVSGVPAPTVTW------LKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGT 105
Query: 62 YTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKG 121
YTC A N +A+ + + V R+ S G +A + V EG+ V C G
Sbjct: 106 YTCVAENTQAEARKDFVVAVLVAPRIRSSG--VAREHH-------VLEGQEVRLDCEADG 156
Query: 122 NPSPWASWDKDGS 134
P P +W KDGS
Sbjct: 157 QPPPDVAWLKDGS 169
Score = 48.0 bits (109), Expect = 3e-05
Identities = 50/179 (27%), Positives = 65/179 (36%), Gaps = 19/179 (10%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYD-DGTARLKIKQVTAEDEGTYTCEAS 67
V C TG P P + W ++ S Y + L+I Q G YTC A
Sbjct: 771 VVLTCHSTGIPAPTVSW---SKAGAQLGARGSGYRVSPSGALEIGQALPIHAGRYTCSAR 827
Query: 68 NCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWA 127
N G A + L V +SP + P+ + V E E V C G P P
Sbjct: 828 NSAGVAHKHVFLTVQ-----ASPVVKPLPSVV-----RAVAE-EEVLLPCEASGIPRPTI 876
Query: 128 SWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
+W K+G + V + L I S ED G Y +N G A RL V
Sbjct: 877 TWQKEGLNVATGVSTQVLPGGQ----LRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVV 931
Score = 41.5 bits (93), Expect = 0.002
Identities = 36/132 (27%), Positives = 54/132 (40%), Gaps = 17/132 (12%)
Query: 49 LKIKQVTAEDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVE 108
L+I++ D+G Y+C+ SN G+A L V Q+ PTF P + V
Sbjct: 1 LEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTV-----------QVPPTFEN-PKTETVS 48
Query: 109 E--GENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
+ G + C V G P+P +W KD + SA V + L++ + G
Sbjct: 49 QVAGSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVVSRG---GRLQLSRLQPAQAGT 105
Query: 167 YRITVENELGRA 178
Y EN A
Sbjct: 106 YTCVAENTQAEA 117
Score = 31.1 bits (67), Expect = 3.2
Identities = 22/74 (29%), Positives = 31/74 (41%), Gaps = 2/74 (2%)
Query: 8 TVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEAS 67
T CQ G P P + W + + +G+ L+I+ V A+D G Y C AS
Sbjct: 605 TALLPCQADGVPAPLVSWRKDRVPLDPRSPRFEILPEGS--LRIQPVLAQDAGHYLCLAS 662
Query: 68 NCLGKAKSNACLVV 81
N G + L V
Sbjct: 663 NSAGSDRQGRDLRV 676
Score = 29.5 bits (63), Expect = 9.6
Identities = 21/79 (26%), Positives = 34/79 (43%), Gaps = 2/79 (2%)
Query: 1 MLSCDGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEG 60
++S G+ V C V G+P + W + + + G L+I +V D G
Sbjct: 236 LVSRPGELVTMVCPVRGSPPIHVSWLKDGLPL-PLSQRTLLHGSGHT-LRISKVQLADAG 293
Query: 61 TYTCEASNCLGKAKSNACL 79
+TC A++ G A N L
Sbjct: 294 IFTCVAASPAGVADRNFTL 312
>AJ277892-5|CAD12459.1| 2154|Homo sapiens Titin Novex-1 Isoform
protein.
Length = 2154
Score = 73.3 bits (172), Expect = 6e-13
Identities = 52/184 (28%), Positives = 79/184 (42%), Gaps = 6/184 (3%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G F ++G P P I W+ +++ + +D L + + ED YTCE
Sbjct: 809 GKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCE 868
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQM---APTFYTYPFNKVVEEGENVTFKCAVKGN 122
A N G A ++A L V + SP ++M P T + V EG+ F+C V G
Sbjct: 869 AKNDYGVATTSASLSV-EVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGT 927
Query: 123 PSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASA 182
SW I PS + + E+ + LEI E ED G Y N +G+ ++A
Sbjct: 928 DLK-VSWYSKDKKIKPSRFFRMTQFEDTYQ-LEIAEAYPEDEGTYTFVASNAVGQVSSTA 985
Query: 183 RLEV 186
L +
Sbjct: 986 NLSL 989
Score = 68.5 bits (160), Expect = 2e-11
Identities = 53/196 (27%), Positives = 76/196 (38%), Gaps = 14/196 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
GD V G P P I+WF ++ AD++ +D L I EDEG YTC
Sbjct: 1198 GDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCM 1257
Query: 66 ASNCLGKAKSNACLVVYH--------------TRRLSSPGRQMAPTFYTYPFNKVVEEGE 111
ASN GK +A L + + L G P F +G
Sbjct: 1258 ASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGL 1317
Query: 112 NVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITV 171
F+ V G P+P +W K+ + S T+ +++ ED G+Y
Sbjct: 1318 PAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKA 1377
Query: 172 ENELGRAEASARLEVI 187
EN LG + +A L V+
Sbjct: 1378 ENMLGESTCAAELLVL 1393
Score = 66.9 bits (156), Expect = 5e-11
Identities = 54/207 (26%), Positives = 88/207 (42%), Gaps = 19/207 (9%)
Query: 2 LSCDGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGT 61
++ +G F+C+V+G D + W+ + I+ F + + T +L+I + EDEGT
Sbjct: 911 VTSEGQPARFQCRVSGT-DLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGT 969
Query: 62 YTCEASNCLGKAKSNACLVV--------------YHTRRLSSPGRQ---MAPTFYTYPFN 104
YT ASN +G+ S A L + +H S ++ P+F +
Sbjct: 970 YTFVASNAVGQVSSTANLSLEGFSKFEENTSNSQWHVSLSVSFKKEPLGQKPSFIQPLSS 1029
Query: 105 KVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEI-MRILEIDEVSIED 163
V GE V F V G P P W + +I P+ + +E M ++ I + E
Sbjct: 1030 LRVHNGETVRFHARVSGIPKPEIQWFHNQQLILPTKDVVFHFEESTGMALMLIVDAYSEH 1089
Query: 164 VGIYRITVENELGRAEASARLEVITRS 190
G Y N G A +A L V ++
Sbjct: 1090 AGQYSCKAANSAGEATCAATLTVTPKA 1116
Score = 60.5 bits (140), Expect = 5e-09
Identities = 50/186 (26%), Positives = 76/186 (40%), Gaps = 13/186 (6%)
Query: 2 LSCDGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAED-EG 60
+S +GD V +T + + W+ +++ F+ D T L I +V ED +G
Sbjct: 1980 VSEEGDIVHLTTSITNAKE--VNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQG 2037
Query: 61 TYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVK 120
Y CEA N GK ++A L V ++ AP V G F C ++
Sbjct: 2038 EYVCEALNDSGKTATSAKLTVV---------KRAAPVIKRKIEPLEVALGHLAKFTCEIQ 2088
Query: 121 GNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEA 180
P+ W K G I S + +++ + I LEI + D G Y NE G
Sbjct: 2089 SAPNVRFQWFKAGREIYESDKCSIRSSKYISS-LEILRTQVVDCGEYTCKASNEYGSVSC 2147
Query: 181 SARLEV 186
+A L V
Sbjct: 2148 TATLTV 2153
Score = 41.9 bits (94), Expect = 0.002
Identities = 38/138 (27%), Positives = 59/138 (42%), Gaps = 10/138 (7%)
Query: 54 VTAEDEGTYTCEASNCLGKAKSNACLV----VYHTRRLSSPGRQMAPTFYTYPFNKVVEE 109
++AE+EG ++ E L K L+ VY T+ S P F N +
Sbjct: 1141 LSAEEEGLHSAELQ--LSKINETLELLSESPVYSTK-FDSEKEGTGPIFIKEVSNADISM 1197
Query: 110 GENVTFKCAVKGNPSPWASWDKDGSIITPSARIT-VKEKEEIMRILEIDEVSIEDVGIYR 168
G+ T V G P P W +G ++TPSA V + ++ I+ +ED G Y
Sbjct: 1198 GDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILF--TKLEDEGEYT 1255
Query: 169 ITVENELGRAEASARLEV 186
N+ G+ SA L++
Sbjct: 1256 CMASNDYGKTICSAYLKI 1273
Score = 38.3 bits (85), Expect = 0.021
Identities = 22/80 (27%), Positives = 35/80 (43%), Gaps = 1/80 (1%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
V+ G+ F + G P P SW K+ +++ + + +L I E ED +
Sbjct: 806 VQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLI-EAFPEDAAV 864
Query: 167 YRITVENELGRAEASARLEV 186
Y +N+ G A SA L V
Sbjct: 865 YTCEAKNDYGVATTSASLSV 884
Score = 35.9 bits (79), Expect = 0.11
Identities = 45/178 (25%), Positives = 69/178 (38%), Gaps = 22/178 (12%)
Query: 11 FECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCL 70
FEC+V NPD W + + + S D RL I +D G YT + +
Sbjct: 195 FECEVA-NPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTYKVAT-- 251
Query: 71 GKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWD 130
+K++A +L ++ T N V E ++ F + W
Sbjct: 252 --SKTSA--------KLKVEAVKIKKTLK----NLTVTETQDAVFTVELTHPNVKGVQWI 297
Query: 131 KDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVIT 188
K+G ++ + + + K I L I +I D +Y LGR ASARL V T
Sbjct: 298 KNGVVLESNEKYAISVKGTIYS-LRIKNCAIVDESVYGF----RLGRLGASARLHVET 350
>AJ277892-4|CAD12458.1| 1294|Homo sapiens Titin Novex-2 Isoform
protein.
Length = 1294
Score = 73.3 bits (172), Expect = 6e-13
Identities = 52/184 (28%), Positives = 79/184 (42%), Gaps = 6/184 (3%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G F ++G P P I W+ +++ + +D L + + ED YTCE
Sbjct: 809 GKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCE 868
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQM---APTFYTYPFNKVVEEGENVTFKCAVKGN 122
A N G A ++A L V + SP ++M P T + V EG+ F+C V G
Sbjct: 869 AKNDYGVATTSASLSV-EVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGT 927
Query: 123 PSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASA 182
SW I PS + + E+ + LEI E ED G Y N +G+ ++A
Sbjct: 928 DLK-VSWYSKDKKIKPSRFFRMTQFEDTYQ-LEIAEAYPEDEGTYTFVASNAVGQVSSTA 985
Query: 183 RLEV 186
L +
Sbjct: 986 NLSL 989
Score = 58.0 bits (134), Expect = 2e-08
Identities = 50/190 (26%), Positives = 73/190 (38%), Gaps = 10/190 (5%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
GDT +F C + + D+ W H I + + S + L I V D+G Y+C
Sbjct: 1105 GDTAQFLCVLKDDSFIDVTWTHEGAKIEESERLKQSQNGNIQFLTICNVQLVDQGLYSCI 1164
Query: 66 ASNCLGKAKSNACLVV-------YHTRRLSSPGRQM--APTFYTYPFNKVVEEGENVTFK 116
N G+ ++A L V H R +M AP V G F
Sbjct: 1165 VHNDCGERTTSAVLSVEGAPESILHERIEQEIEMEMKAAPVIKRKIEPLEVALGHLAKFT 1224
Query: 117 CAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG 176
C ++ P+ W K G I S + +++ + I LEI + D G Y NE G
Sbjct: 1225 CEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISS-LEILRTQVVDCGEYTCKASNEYG 1283
Query: 177 RAEASARLEV 186
+A L V
Sbjct: 1284 SVSCTATLTV 1293
Score = 42.3 bits (95), Expect = 0.001
Identities = 26/92 (28%), Positives = 42/92 (45%), Gaps = 1/92 (1%)
Query: 95 APTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRIL 154
AP + + + V+ G+ F C +K + +W +G+ I S R+ + I + L
Sbjct: 1090 APKIFLHLQDVTVKCGDTAQFLCVLKDDSFIDVTWTHEGAKIEESERLKQSQNGNI-QFL 1148
Query: 155 EIDEVSIEDVGIYRITVENELGRAEASARLEV 186
I V + D G+Y V N+ G SA L V
Sbjct: 1149 TICNVQLVDQGLYSCIVHNDCGERTTSAVLSV 1180
Score = 38.3 bits (85), Expect = 0.021
Identities = 22/80 (27%), Positives = 35/80 (43%), Gaps = 1/80 (1%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
V+ G+ F + G P P SW K+ +++ + + +L I E ED +
Sbjct: 806 VQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLI-EAFPEDAAV 864
Query: 167 YRITVENELGRAEASARLEV 186
Y +N+ G A SA L V
Sbjct: 865 YTCEAKNDYGVATTSASLSV 884
Score = 35.9 bits (79), Expect = 0.11
Identities = 45/178 (25%), Positives = 69/178 (38%), Gaps = 22/178 (12%)
Query: 11 FECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCL 70
FEC+V NPD W + + + S D RL I +D G YT + +
Sbjct: 195 FECEVA-NPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTYKVAT-- 251
Query: 71 GKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWD 130
+K++A +L ++ T N V E ++ F + W
Sbjct: 252 --SKTSA--------KLKVEAVKIKKTLK----NLTVTETQDAVFTVELTHPNVKGVQWI 297
Query: 131 KDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVIT 188
K+G ++ + + + K I L I +I D +Y LGR ASARL V T
Sbjct: 298 KNGVVLESNEKYAISVKGTIYS-LRIKNCAIVDESVYGF----RLGRLGASARLHVET 350
>U35234-1|AAC50299.1| 1948|Homo sapiens protein tyrosine phosphatase
sigma protein.
Length = 1948
Score = 72.9 bits (171), Expect = 8e-13
Identities = 60/198 (30%), Positives = 79/198 (39%), Gaps = 19/198 (9%)
Query: 2 LSCDGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGT-ARLKIKQV-TAEDE 59
+ G F CQ TG+P P + W + + +D+ A L+I+ + T DE
Sbjct: 43 IGVSGGVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESAGAVLRIQPLRTPRDE 102
Query: 60 GTYTCEASNCLGKAKSNACLVVYHTRRLSS--PGRQMAPTFYTYPFNKVVEEGENVTFKC 117
Y C A N +G+ +A L V +L S P M P KVVE T C
Sbjct: 103 NVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQL------KVVERTRTATMLC 156
Query: 118 AVKGNPSPWASWDKDGSIITPSA--------RITVKEKEEIMRILEIDEVSIEDVGIYRI 169
A GNP P +W KD + PSA R E I L+I+ D G Y
Sbjct: 157 AASGNPDPEITWFKDFLPVDPSASNGRIKQLRSETFESTPIRGALQIESSEETDQGKYEC 216
Query: 170 TVENELG-RAEASARLEV 186
N G R + A L V
Sbjct: 217 VATNSAGVRYSSPANLYV 234
Score = 67.3 bits (157), Expect = 4e-11
Identities = 55/191 (28%), Positives = 83/191 (43%), Gaps = 25/191 (13%)
Query: 8 TVEFECQVTGNPDPDIRWFHYAEVIRDCAD-----------FESSYDDGTARLKIKQVTA 56
T C +GNPDP+I WF + A FES+ G +++ + T
Sbjct: 151 TATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRSETFESTPIRGALQIESSEET- 209
Query: 57 EDEGTYTCEASNCLG-KAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTF 115
D+G Y C A+N G + S A L V R + R++AP F P + + G NV
Sbjct: 210 -DQGKYECVATNSAGVRYSSPANLYVRELREV----RRVAPRFSILPMSHEIMPGGNVNI 264
Query: 116 KCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENEL 175
C G+P P+ W + +TP + V +LE+ +V +D Y + L
Sbjct: 265 TCVAVGSPMPYVKWMQGAEDLTPEDDMPVGR-----NVLELTDV--KDSANYTCVAMSSL 317
Query: 176 GRAEASARLEV 186
G EA A++ V
Sbjct: 318 GVIEAVAQITV 328
Score = 46.8 bits (106), Expect = 6e-05
Identities = 29/122 (23%), Positives = 51/122 (41%), Gaps = 2/122 (1%)
Query: 96 PTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILE 155
P F P +++ G +F C G+P P +W+K G + T++ E +L
Sbjct: 33 PRFIKEPKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESAGAVLR 92
Query: 156 IDEV-SIEDVGIYRITVENELGRAEASARLEVITRSGKFYGGLRAYSASPRKCLSYRRRP 214
I + + D +Y +N +G A+L V+ R + G P+ + R R
Sbjct: 93 IQPLRTPRDENVYECVAQNSVGEITVHAKLTVL-REDQLPSGFPNIDMGPQLKVVERTRT 151
Query: 215 ST 216
+T
Sbjct: 152 AT 153
Score = 34.3 bits (75), Expect = 0.34
Identities = 21/76 (27%), Positives = 31/76 (40%), Gaps = 6/76 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G V C G+P P ++W AE D D R ++ +D YTC
Sbjct: 259 GGNVNITCVAVGSPMPYVKWMQGAE------DLTPEDDMPVGRNVLELTDVKDSANYTCV 312
Query: 66 ASNCLGKAKSNACLVV 81
A + LG ++ A + V
Sbjct: 313 AMSSLGVIEAVAQITV 328
>X68274-1|CAA48335.1| 1040|Homo sapiens TAG-1/axonin-1 precursor
protein.
Length = 1040
Score = 72.5 bits (170), Expect = 1e-12
Identities = 52/181 (28%), Positives = 75/181 (41%), Gaps = 22/181 (12%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G V EC GNP P I+W + L+I V+ EDEGTY CE
Sbjct: 254 GQQVTLECFAFGNPVPRIKWRKVD------GSLSPQWTTAEPTLQIPSVSFEDEGTYECE 307
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A N G+ ++V Q P + + + G N+ + CA G P P
Sbjct: 308 AENSKGRDTVQGRIIV-----------QAQPEWLKVISDTEADIGSNLRWGCAAAGKPRP 356
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
W ++G + R+ V + L ++S+ED G+Y+ EN+ G ASA L
Sbjct: 357 TVRWLRNGEPLASQNRVEVLAGD-----LRFSKLSLEDSGMYQCVAENKHGTIYASAELA 411
Query: 186 V 186
V
Sbjct: 412 V 412
Score = 61.3 bits (142), Expect = 3e-09
Identities = 47/183 (25%), Positives = 74/183 (40%), Gaps = 20/183 (10%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G + + C G P P +RW E + E D L+ +++ ED G Y C
Sbjct: 341 GSNLRWGCAAAGKPRPTVRWLRNGEPLASQNRVEVLAGD----LRFSKLSLEDSGMYQCV 396
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVE--EGENVTFKCAVKGNP 123
A N G ++A L V + +AP F P +++ G + C + P
Sbjct: 397 AENKHGTIYASAELAV----------QALAPDFRLNPVRRLIPAARGGEILIPCQPRAAP 446
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
W K I+ S+R+TV ++ I +S D G Y EN +G+A ++
Sbjct: 447 KAVVLWSKGTEILVNSSRVTVTPDGTLI----IRNISRSDEGKYTCFAENFMGKANSTGI 502
Query: 184 LEV 186
L V
Sbjct: 503 LSV 505
Score = 54.8 bits (126), Expect = 2e-07
Identities = 43/143 (30%), Positives = 59/143 (41%), Gaps = 10/143 (6%)
Query: 46 TARLKIKQVTAEDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYT-YPFN 104
T L I + A D G Y+C A++ + + + + R AP+ +P
Sbjct: 189 TGNLYIARTNASDLGNYSCLATSHMDFSTKSVFSKFAQLNLAAEDTRLFAPSIKARFPAE 248
Query: 105 KVVEEGENVTFKCAVKGNPSPWASWDK-DGSIITPSARITVKEKEEIMRILEIDEVSIED 163
G+ VT +C GNP P W K DGS+ S + T E L+I VS ED
Sbjct: 249 TYALVGQQVTLECFAFGNPVPRIKWRKVDGSL---SPQWTTAEP-----TLQIPSVSFED 300
Query: 164 VGIYRITVENELGRAEASARLEV 186
G Y EN GR R+ V
Sbjct: 301 EGTYECEAENSKGRDTVQGRIIV 323
Score = 44.4 bits (100), Expect = 3e-04
Identities = 32/119 (26%), Positives = 55/119 (46%), Gaps = 14/119 (11%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G + CQ P + W E++ + + + DGT L I+ ++ DEG YTC
Sbjct: 433 GGEILIPCQPRAAPKAVVLWSKGTEILVNSSRVTVT-PDGT--LIIRNISRSDEGKYTCF 489
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
A N +GKA S L V +++ +AP+ + + G+N+T +C +P+
Sbjct: 490 AENFMGKANSTGILSVRDATKIT-----LAPS------SADINLGDNLTLQCHASHDPT 537
>X67734-1|CAA47963.1| 1040|Homo sapiens transient axonal
glycoprotein protein.
Length = 1040
Score = 72.5 bits (170), Expect = 1e-12
Identities = 52/181 (28%), Positives = 75/181 (41%), Gaps = 22/181 (12%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G V EC GNP P I+W + L+I V+ EDEGTY CE
Sbjct: 254 GQQVTLECFAFGNPVPRIKWRKVD------GSLSPQWTTAEPTLQIPSVSFEDEGTYECE 307
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A N G+ ++V Q P + + + G N+ + CA G P P
Sbjct: 308 AENSKGRDTVQGRIIV-----------QAQPEWLKVISDTEADIGSNLRWGCAAAGKPRP 356
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
W ++G + R+ V + L ++S+ED G+Y+ EN+ G ASA L
Sbjct: 357 TVRWLRNGEPLASQNRVEVLAGD-----LRFSKLSLEDSGMYQCVAENKHGTIYASAELA 411
Query: 186 V 186
V
Sbjct: 412 V 412
Score = 61.3 bits (142), Expect = 3e-09
Identities = 47/183 (25%), Positives = 74/183 (40%), Gaps = 20/183 (10%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G + + C G P P +RW E + E D L+ +++ ED G Y C
Sbjct: 341 GSNLRWGCAAAGKPRPTVRWLRNGEPLASQNRVEVLAGD----LRFSKLSLEDSGMYQCV 396
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVE--EGENVTFKCAVKGNP 123
A N G ++A L V + +AP F P +++ G + C + P
Sbjct: 397 AENKHGTIYASAELAV----------QALAPDFRLNPVRRLIPAARGGEILIPCQPRAAP 446
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
W K I+ S+R+TV ++ I +S D G Y EN +G+A ++
Sbjct: 447 KAVVLWSKGTEILVNSSRVTVTPDGTLI----IRNISRSDEGKYTCFAENFMGKANSTGI 502
Query: 184 LEV 186
L V
Sbjct: 503 LSV 505
Score = 54.8 bits (126), Expect = 2e-07
Identities = 43/143 (30%), Positives = 59/143 (41%), Gaps = 10/143 (6%)
Query: 46 TARLKIKQVTAEDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYT-YPFN 104
T L I + A D G Y+C A++ + + + + R AP+ +P
Sbjct: 189 TGNLYIARTNASDLGNYSCLATSHMDFSTKSVFSKFAQLNLAAEDTRLFAPSIKARFPAE 248
Query: 105 KVVEEGENVTFKCAVKGNPSPWASWDK-DGSIITPSARITVKEKEEIMRILEIDEVSIED 163
G+ VT +C GNP P W K DGS+ S + T E L+I VS ED
Sbjct: 249 TYALVGQQVTLECFAFGNPVPRIKWRKVDGSL---SPQWTTAEP-----TLQIPSVSFED 300
Query: 164 VGIYRITVENELGRAEASARLEV 186
G Y EN GR R+ V
Sbjct: 301 EGTYECEAENSKGRDTVQGRIIV 323
Score = 44.4 bits (100), Expect = 3e-04
Identities = 32/119 (26%), Positives = 55/119 (46%), Gaps = 14/119 (11%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G + CQ P + W E++ + + + DGT L I+ ++ DEG YTC
Sbjct: 433 GGEILIPCQPRAAPKAVVLWSKGTEILVNSSRVTVT-PDGT--LIIRNISRSDEGKYTCF 489
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
A N +GKA S L V +++ +AP+ + + G+N+T +C +P+
Sbjct: 490 AENFMGKANSTGILSVRDATKIT-----LAPS------SADINLGDNLTLQCHASHDPT 537
>BC129986-1|AAI29987.1| 1040|Homo sapiens contactin 2 (axonal)
protein.
Length = 1040
Score = 72.5 bits (170), Expect = 1e-12
Identities = 52/181 (28%), Positives = 75/181 (41%), Gaps = 22/181 (12%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G V EC GNP P I+W + L+I V+ EDEGTY CE
Sbjct: 254 GQQVTLECFAFGNPVPRIKWRKVD------GSLSPQWTTAEPTLQIPSVSFEDEGTYECE 307
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A N G+ ++V Q P + + + G N+ + CA G P P
Sbjct: 308 AENSKGRDTVQGRIIV-----------QAQPEWLKVISDTEADIGSNLRWGCAAAGKPRP 356
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
W ++G + R+ V + L ++S+ED G+Y+ EN+ G ASA L
Sbjct: 357 TVRWLRNGEPLASQNRVEVLAGD-----LRFSKLSLEDSGMYQCVAENKHGTIYASAELA 411
Query: 186 V 186
V
Sbjct: 412 V 412
Score = 61.3 bits (142), Expect = 3e-09
Identities = 47/183 (25%), Positives = 74/183 (40%), Gaps = 20/183 (10%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G + + C G P P +RW E + E D L+ +++ ED G Y C
Sbjct: 341 GSNLRWGCAAAGKPRPTVRWLRNGEPLASQNRVEVLAGD----LRFSKLSLEDSGMYQCV 396
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVE--EGENVTFKCAVKGNP 123
A N G ++A L V + +AP F P +++ G + C + P
Sbjct: 397 AENKHGTIYASAELAV----------QALAPDFRLNPVRRLIPAARGGEILIPCQPRAAP 446
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
W K I+ S+R+TV ++ I +S D G Y EN +G+A ++
Sbjct: 447 KAVVLWSKGTEILVNSSRVTVTPDGTLI----IRNISRSDEGKYTCFAENFMGKANSTGI 502
Query: 184 LEV 186
L V
Sbjct: 503 LSV 505
Score = 54.8 bits (126), Expect = 2e-07
Identities = 43/143 (30%), Positives = 59/143 (41%), Gaps = 10/143 (6%)
Query: 46 TARLKIKQVTAEDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYT-YPFN 104
T L I + A D G Y+C A++ + + + + R AP+ +P
Sbjct: 189 TGNLYIARTNASDLGNYSCLATSHMDFSTKSVFSKFAQLNLAAEDTRLFAPSIKARFPAE 248
Query: 105 KVVEEGENVTFKCAVKGNPSPWASWDK-DGSIITPSARITVKEKEEIMRILEIDEVSIED 163
G+ VT +C GNP P W K DGS+ S + T E L+I VS ED
Sbjct: 249 TYALVGQQVTLECFAFGNPVPRIKWRKVDGSL---SPQWTTAEP-----TLQIPSVSFED 300
Query: 164 VGIYRITVENELGRAEASARLEV 186
G Y EN GR R+ V
Sbjct: 301 EGTYECEAENSKGRDTVQGRIIV 323
Score = 44.4 bits (100), Expect = 3e-04
Identities = 32/119 (26%), Positives = 55/119 (46%), Gaps = 14/119 (11%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G + CQ P + W E++ + + + DGT L I+ ++ DEG YTC
Sbjct: 433 GGEILIPCQPRAAPKAVVLWSKGTEILVNSSRVTVT-PDGT--LIIRNISRSDEGKYTCF 489
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
A N +GKA S L V +++ +AP+ + + G+N+T +C +P+
Sbjct: 490 AENFMGKANSTGILSVRDATKIT-----LAPS------SADINLGDNLTLQCHASHDPT 537
>BC114435-1|AAI14436.1| 1264|Homo sapiens Cdon homolog (mouse)
protein.
Length = 1264
Score = 72.5 bits (170), Expect = 1e-12
Identities = 54/183 (29%), Positives = 79/183 (43%), Gaps = 19/183 (10%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
V EC V+G P P + W + I +++ Y + L V D G Y+C A N
Sbjct: 239 VTLECVVSGVPAPQVYWLKDGQDIAPGSNWRRLY----SHLATDSVDPADSGNYSCMAGN 294
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G K +V S G Q +++V G V F C V GNP+P +
Sbjct: 295 KSGDVKYVTYMVNVLEHASISKGLQ----------DQIVSLGATVHFTCDVHGNPAPNCT 344
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVIT 188
W + I PSAR L+I V++EDVG+Y+ +N +G ++ RLE+
Sbjct: 345 WFHNAQPIHPSARHLTAGNG-----LKISGVTVEDVGMYQCVADNGIGFMHSTGRLEIEN 399
Query: 189 RSG 191
G
Sbjct: 400 DGG 402
Score = 71.7 bits (168), Expect = 2e-12
Identities = 49/159 (30%), Positives = 69/159 (43%), Gaps = 11/159 (6%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G TV F C V GNP P+ WFH A+ I A ++ + LKI VT ED G Y C
Sbjct: 326 GATVHFTCDVHGNPAPNCTWFHNAQPIHPSARHLTAGNG----LKISGVTVEDVGMYQCV 381
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A N +G S L + + G P T P + V +G+ VT C G P P
Sbjct: 382 ADNGIGFMHSTGRL------EIENDG-GFKPVIITAPVSAKVADGDFVTLSCNASGLPVP 434
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDV 164
W +IT ++ K ++ + +++E V
Sbjct: 435 VIRWYDSHGLITSHPSQVLRSKSRKSQLSRPEGLNLEPV 473
Score = 39.1 bits (87), Expect = 0.012
Identities = 32/100 (32%), Positives = 45/100 (45%), Gaps = 23/100 (23%)
Query: 5 DGDTVEFECQVTGNPDPDIRWF--------HYAEVIRDCA-----------DFESSY--- 42
DGD V C +G P P IRW+ H ++V+R + + E Y
Sbjct: 418 DGDFVTLSCNASGLPVPVIRWYDSHGLITSHPSQVLRSKSRKSQLSRPEGLNLEPVYFVL 477
Query: 43 -DDGTARLKIKQVTAEDEGTYTCEASNCLGKAKSNACLVV 81
G + L I+ VT E G Y CEA+N G ++ A L+V
Sbjct: 478 SQAGASSLHIQAVTQEHAGKYICEAANEHGTTQAEASLMV 517
>BC067107-1|AAH67107.1| 814|Homo sapiens putative neuronal cell
adhesion molecule protein.
Length = 814
Score = 72.5 bits (170), Expect = 1e-12
Identities = 53/184 (28%), Positives = 74/184 (40%), Gaps = 15/184 (8%)
Query: 8 TVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEAS 67
T EC TGNP P + W + + E GT L I VT + G Y C A+
Sbjct: 254 TAVLECVATGNPRPIVSW---SRLDGRPIGVEGIQVLGTGNLIISDVTVQHSGVYVCAAN 310
Query: 68 NCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWA 127
+ + A RL Q F +P + G F C +G P P
Sbjct: 311 RPGTRVRRTA------QGRLVV---QAPAEFVQHPQSISRPAGTTAMFTCQAQGEPPPHV 361
Query: 128 SWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVI 187
+W K+G ++ P + +K L I + ED IY+ EN G ++ASARL V+
Sbjct: 362 TWLKNGQVLGPGGHVRLKNNNS---TLTISGIGPEDEAIYQCVAENSAGSSQASARLTVL 418
Query: 188 TRSG 191
G
Sbjct: 419 WAEG 422
Score = 51.6 bits (118), Expect = 2e-06
Identities = 50/187 (26%), Positives = 79/187 (42%), Gaps = 21/187 (11%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQV----TAEDEGT 61
G + +C+V G P I W + + + + +G+ ++ ++ + DEG
Sbjct: 56 GQPIVLDCRVEGTPPVRITWRKNGVELPE-STHSTLLANGSLMIRHFRLEPGGSPSDEGD 114
Query: 62 YTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKG 121
Y C A N G LVV R+ + F+ +P V EEG F+C + G
Sbjct: 115 YECVAQNRFG-------LVVSRKARIQAATMS---DFHVHPQATVGEEGGVARFQCQIHG 164
Query: 122 NPSPWASWDKDG-SIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG-RAE 179
P P +W+K+ I T + R T+ K +L+I + ED GI+ N R
Sbjct: 165 LPKPLITWEKNRVPIDTDNERYTLLPK----GVLQITGLRAEDGGIFHCVASNIASIRIS 220
Query: 180 ASARLEV 186
ARL V
Sbjct: 221 HGARLTV 227
Score = 50.4 bits (115), Expect = 5e-06
Identities = 51/186 (27%), Positives = 73/186 (39%), Gaps = 15/186 (8%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G F+CQ+ G P P I W I + + G L+I + AED G + C
Sbjct: 152 EGGVARFQCQIHGLPKPLITWEKNRVPIDTDNERYTLLPKGV--LQITGLRAEDGGIFHC 209
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
ASN S+ + T S G P P N + + +C GNP
Sbjct: 210 VASNIASIRISHGARL---TVSGSGSGAYKEPAILVGPENLTLTVHQTAVLECVATGNPR 266
Query: 125 PWASWDK-DGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG---RAEA 180
P SW + DG I I V ++ I +V+++ G+Y + N G R A
Sbjct: 267 PIVSWSRLDGRPIGVEG-IQVLGTGNLI----ISDVTVQHSGVY-VCAANRPGTRVRRTA 320
Query: 181 SARLEV 186
RL V
Sbjct: 321 QGRLVV 326
Score = 49.6 bits (113), Expect = 8e-06
Identities = 27/89 (30%), Positives = 38/89 (42%), Gaps = 2/89 (2%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G T F CQ G P P + W +V+ ++ T L I + EDE Y C
Sbjct: 344 GTTAMFTCQAQGEPPPHVTWLKNGQVLGPGGHVRLKNNNST--LTISGIGPEDEAIYQCV 401
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQM 94
A N G ++++A L V L P R +
Sbjct: 402 AENSAGSSQASARLTVLWAEGLPGPPRNV 430
Score = 35.1 bits (77), Expect = 0.19
Identities = 26/103 (25%), Positives = 40/103 (38%), Gaps = 3/103 (2%)
Query: 91 GRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEI 150
G F P + V G+ + C V+G P +W K+G + S T+ +
Sbjct: 37 GHSAELAFAVEPSDDVAVPGQPIVLDCRVEGTPPVRITWRKNGVELPESTHSTLLANGSL 96
Query: 151 M-RILEIDE-VSIEDVGIYRITVENELGR-AEASARLEVITRS 190
M R ++ S D G Y +N G AR++ T S
Sbjct: 97 MIRHFRLEPGGSPSDEGDYECVAQNRFGLVVSRKARIQAATMS 139
>BC042054-1|AAH42054.1| 814|Homo sapiens putative neuronal cell
adhesion molecule protein.
Length = 814
Score = 72.5 bits (170), Expect = 1e-12
Identities = 53/184 (28%), Positives = 74/184 (40%), Gaps = 15/184 (8%)
Query: 8 TVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEAS 67
T EC TGNP P + W + + E GT L I VT + G Y C A+
Sbjct: 254 TAVLECVATGNPRPIVSW---SRLDGRPIGVEGIQVLGTGNLIISDVTVQHSGVYVCAAN 310
Query: 68 NCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWA 127
+ + A RL Q F +P + G F C +G P P
Sbjct: 311 RPGTRVRRTA------QGRLVV---QAPAEFVQHPQSISRPAGTTAMFTCQAQGEPPPHV 361
Query: 128 SWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVI 187
+W K+G ++ P + +K L I + ED IY+ EN G ++ASARL V+
Sbjct: 362 TWLKNGQVLGPGGHVRLKNNNS---TLTISGIGPEDEAIYQCVAENSAGSSQASARLTVL 418
Query: 188 TRSG 191
G
Sbjct: 419 WAEG 422
Score = 51.6 bits (118), Expect = 2e-06
Identities = 50/187 (26%), Positives = 79/187 (42%), Gaps = 21/187 (11%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQV----TAEDEGT 61
G + +C+V G P I W + + + + +G+ ++ ++ + DEG
Sbjct: 56 GQPIVLDCRVEGTPPVRITWRKNGVELPE-STHSTLLANGSLMIRHFRLEPGGSPSDEGD 114
Query: 62 YTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKG 121
Y C A N G LVV R+ + F+ +P V EEG F+C + G
Sbjct: 115 YECVAQNRFG-------LVVSRKARIQAATMS---DFHVHPQATVGEEGGVARFQCQIHG 164
Query: 122 NPSPWASWDKDG-SIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG-RAE 179
P P +W+K+ I T + R T+ K +L+I + ED GI+ N R
Sbjct: 165 LPKPLITWEKNRVPIDTDNERYTLLPK----GVLQITGLRAEDGGIFHCVASNIASIRIS 220
Query: 180 ASARLEV 186
ARL V
Sbjct: 221 HGARLTV 227
Score = 50.4 bits (115), Expect = 5e-06
Identities = 51/186 (27%), Positives = 73/186 (39%), Gaps = 15/186 (8%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G F+CQ+ G P P I W I + + G L+I + AED G + C
Sbjct: 152 EGGVARFQCQIHGLPKPLITWEKNRVPIDTDNERYTLLPKGV--LQITGLRAEDGGIFHC 209
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
ASN S+ + T S G P P N + + +C GNP
Sbjct: 210 VASNIASIRISHGARL---TVSGSGSGAYKEPAILVGPENLTLTVHQTAVLECVATGNPR 266
Query: 125 PWASWDK-DGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG---RAEA 180
P SW + DG I I V ++ I +V+++ G+Y + N G R A
Sbjct: 267 PIVSWSRLDGRPIGVEG-IQVLGTGNLI----ISDVTVQHSGVY-VCAANRPGTRVRRTA 320
Query: 181 SARLEV 186
RL V
Sbjct: 321 QGRLVV 326
Score = 49.6 bits (113), Expect = 8e-06
Identities = 27/89 (30%), Positives = 38/89 (42%), Gaps = 2/89 (2%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G T F CQ G P P + W +V+ ++ T L I + EDE Y C
Sbjct: 344 GTTAMFTCQAQGEPPPHVTWLKNGQVLGPGGHVRLKNNNST--LTISGIGPEDEAIYQCV 401
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQM 94
A N G ++++A L V L P R +
Sbjct: 402 AENSAGSSQASARLTVLWAEGLPGPPRNV 430
Score = 35.1 bits (77), Expect = 0.19
Identities = 26/103 (25%), Positives = 40/103 (38%), Gaps = 3/103 (2%)
Query: 91 GRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEI 150
G F P + V G+ + C V+G P +W K+G + S T+ +
Sbjct: 37 GHSAELAFAVEPSDDVAVPGQPIVLDCRVEGTPPVRITWRKNGVELPESTHSTLLANGSL 96
Query: 151 M-RILEIDE-VSIEDVGIYRITVENELGR-AEASARLEVITRS 190
M R ++ S D G Y +N G AR++ T S
Sbjct: 97 MIRHFRLEPGGSPSDEGDYECVAQNRFGLVVSRKARIQAATMS 139
>AL583832-3|CAI15288.1| 1040|Homo sapiens contactin 2 (axonal)
protein.
Length = 1040
Score = 72.5 bits (170), Expect = 1e-12
Identities = 52/181 (28%), Positives = 75/181 (41%), Gaps = 22/181 (12%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G V EC GNP P I+W + L+I V+ EDEGTY CE
Sbjct: 254 GQQVTLECFAFGNPVPRIKWRKVD------GSLSPQWTTAEPTLQIPSVSFEDEGTYECE 307
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A N G+ ++V Q P + + + G N+ + CA G P P
Sbjct: 308 AENSKGRDTVQGRIIV-----------QAQPEWLKVISDTEADIGSNLRWGCAAAGKPRP 356
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
W ++G + R+ V + L ++S+ED G+Y+ EN+ G ASA L
Sbjct: 357 TVRWLRNGEPLASQNRVEVLAGD-----LRFSKLSLEDSGMYQCVAENKHGTIYASAELA 411
Query: 186 V 186
V
Sbjct: 412 V 412
Score = 61.3 bits (142), Expect = 3e-09
Identities = 47/183 (25%), Positives = 74/183 (40%), Gaps = 20/183 (10%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G + + C G P P +RW E + E D L+ +++ ED G Y C
Sbjct: 341 GSNLRWGCAAAGKPRPTVRWLRNGEPLASQNRVEVLAGD----LRFSKLSLEDSGMYQCV 396
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVE--EGENVTFKCAVKGNP 123
A N G ++A L V + +AP F P +++ G + C + P
Sbjct: 397 AENKHGTIYASAELAV----------QALAPDFRLNPVRRLIPAARGGEILIPCQPRAAP 446
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
W K I+ S+R+TV ++ I +S D G Y EN +G+A ++
Sbjct: 447 KAVVLWSKGTEILVNSSRVTVTPDGTLI----IRNISRSDEGKYTCFAENFMGKANSTGI 502
Query: 184 LEV 186
L V
Sbjct: 503 LSV 505
Score = 54.8 bits (126), Expect = 2e-07
Identities = 43/143 (30%), Positives = 59/143 (41%), Gaps = 10/143 (6%)
Query: 46 TARLKIKQVTAEDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYT-YPFN 104
T L I + A D G Y+C A++ + + + + R AP+ +P
Sbjct: 189 TGNLYIARTNASDLGNYSCLATSHMDFSTKSVFSKFAQLNLAAEDTRLFAPSIKARFPAE 248
Query: 105 KVVEEGENVTFKCAVKGNPSPWASWDK-DGSIITPSARITVKEKEEIMRILEIDEVSIED 163
G+ VT +C GNP P W K DGS+ S + T E L+I VS ED
Sbjct: 249 TYALVGQQVTLECFAFGNPVPRIKWRKVDGSL---SPQWTTAEP-----TLQIPSVSFED 300
Query: 164 VGIYRITVENELGRAEASARLEV 186
G Y EN GR R+ V
Sbjct: 301 EGTYECEAENSKGRDTVQGRIIV 323
Score = 44.4 bits (100), Expect = 3e-04
Identities = 32/119 (26%), Positives = 55/119 (46%), Gaps = 14/119 (11%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G + CQ P + W E++ + + + DGT L I+ ++ DEG YTC
Sbjct: 433 GGEILIPCQPRAAPKAVVLWSKGTEILVNSSRVTVT-PDGT--LIIRNISRSDEGKYTCF 489
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
A N +GKA S L V +++ +AP+ + + G+N+T +C +P+
Sbjct: 490 AENFMGKANSTGILSVRDATKIT-----LAPS------SADINLGDNLTLQCHASHDPT 537
>BC098583-1|AAH98583.1| 1287|Homo sapiens Cdon homolog (mouse)
protein.
Length = 1287
Score = 72.1 bits (169), Expect = 1e-12
Identities = 54/183 (29%), Positives = 79/183 (43%), Gaps = 19/183 (10%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
V EC V+G P P + W + I +++ Y + L V D G Y+C A N
Sbjct: 239 VTLECVVSGVPAPQVYWLKDGQDIAPESNWRRLY----SHLATDSVDPADSGNYSCMAGN 294
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G K +V S G Q +++V G V F C V GNP+P +
Sbjct: 295 KSGDVKYVTYMVNVLEHASISKGLQ----------DQIVSLGATVHFTCDVHGNPAPNCT 344
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVIT 188
W + I PSAR L+I V++EDVG+Y+ +N +G ++ RLE+
Sbjct: 345 WFHNAQPIHPSARHLTAGNG-----LKISGVTVEDVGMYQCVADNGIGFMHSTGRLEIEN 399
Query: 189 RSG 191
G
Sbjct: 400 DGG 402
Score = 71.7 bits (168), Expect = 2e-12
Identities = 49/159 (30%), Positives = 69/159 (43%), Gaps = 11/159 (6%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G TV F C V GNP P+ WFH A+ I A ++ + LKI VT ED G Y C
Sbjct: 326 GATVHFTCDVHGNPAPNCTWFHNAQPIHPSARHLTAGNG----LKISGVTVEDVGMYQCV 381
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A N +G S L + + G P T P + V +G+ VT C G P P
Sbjct: 382 ADNGIGFMHSTGRL------EIENDG-GFKPVIITAPVSAKVADGDFVTLSCNASGLPVP 434
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDV 164
W +IT ++ K ++ + +++E V
Sbjct: 435 VIRWYDSHGLITSHPSQVLRSKSRKSQLSRPEGLNLEPV 473
Score = 39.1 bits (87), Expect = 0.012
Identities = 32/100 (32%), Positives = 45/100 (45%), Gaps = 23/100 (23%)
Query: 5 DGDTVEFECQVTGNPDPDIRWF--------HYAEVIRDCA-----------DFESSY--- 42
DGD V C +G P P IRW+ H ++V+R + + E Y
Sbjct: 418 DGDFVTLSCNASGLPVPVIRWYDSHGLITSHPSQVLRSKSRKSQLSRPEGLNLEPVYFVL 477
Query: 43 -DDGTARLKIKQVTAEDEGTYTCEASNCLGKAKSNACLVV 81
G + L I+ VT E G Y CEA+N G ++ A L+V
Sbjct: 478 SQAGASSLHIQAVTQEHAGKYICEAANEHGTTQAEASLMV 517
>BC109099-1|AAI09100.1| 773|Homo sapiens MUSK protein protein.
Length = 773
Score = 71.7 bits (168), Expect = 2e-12
Identities = 58/182 (31%), Positives = 75/182 (41%), Gaps = 18/182 (9%)
Query: 7 DTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEA 66
+ F C V P P+I W +I+ D S + L I V D+G Y C A
Sbjct: 43 EVATFMCAVESYPQPEISWTRNKILIK-LFDTRYSIRENGQLLTILSVEDSDDGIYCCTA 101
Query: 67 SNCLGKA-KSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
+N +G A +S L V +M P P N + EG C GNP P
Sbjct: 102 NNGVGGAVESCGALQV-----------KMKPKITRPPINVKIIEGLKAVLPCTTMGNPKP 150
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEAS-ARL 184
SW K S + ++RI V E L I V ED G YR +N LG A + +L
Sbjct: 151 SVSWIKGDSPLRENSRIAVLESGS----LRIHNVQKEDAGQYRCVAKNSLGTAYSKVVKL 206
Query: 185 EV 186
EV
Sbjct: 207 EV 208
Score = 50.0 bits (114), Expect = 6e-06
Identities = 47/173 (27%), Positives = 75/173 (43%), Gaps = 20/173 (11%)
Query: 13 CQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLGK 72
C GNP P + W +R+ + + + G+ L+I V ED G Y C A N LG
Sbjct: 142 CTTMGNPKPSVSWIKGDSPLRENSRI-AVLESGS--LRIHNVQKEDAGQYRCVAKNSLGT 198
Query: 73 AKSNAC-LVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDK 131
A S L V R+ AP + F G VT C G P P +W +
Sbjct: 199 AYSKVVKLEVEVFARILR-----APESHNVTF------GSFVTLHCTATGIPVPTITWIE 247
Query: 132 DGSIITP-SARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
+G+ ++ S + +VK++ R+ ++ I G+Y N+ G ++A+
Sbjct: 248 NGNAVSSGSIQESVKDRVIDSRL----QLFITKPGLYTCIATNKHGEKFSTAK 296
Score = 32.7 bits (71), Expect = 1.0
Identities = 21/72 (29%), Positives = 28/72 (38%), Gaps = 2/72 (2%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G V C TG P P I W + + S D ++ Q+ G YTC
Sbjct: 226 GSFVTLHCTATGIPVPTITWIENGNAV-SSGSIQESVKDRVIDSRL-QLFITKPGLYTCI 283
Query: 66 ASNCLGKAKSNA 77
A+N G+ S A
Sbjct: 284 ATNKHGEKFSTA 295
>BC109098-1|AAI09099.1| 783|Homo sapiens MUSK protein protein.
Length = 783
Score = 71.7 bits (168), Expect = 2e-12
Identities = 58/182 (31%), Positives = 75/182 (41%), Gaps = 18/182 (9%)
Query: 7 DTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEA 66
+ F C V P P+I W +I+ D S + L I V D+G Y C A
Sbjct: 43 EVATFMCAVESYPQPEISWTRNKILIK-LFDTRYSIRENGQLLTILSVEDSDDGIYCCTA 101
Query: 67 SNCLGKA-KSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
+N +G A +S L V +M P P N + EG C GNP P
Sbjct: 102 NNGVGGAVESCGALQV-----------KMKPKITRPPINVKIIEGLKAVLPCTTMGNPKP 150
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEAS-ARL 184
SW K S + ++RI V E L I V ED G YR +N LG A + +L
Sbjct: 151 SVSWIKGDSPLRENSRIAVLESGS----LRIHNVQKEDAGQYRCVAKNSLGTAYSKVVKL 206
Query: 185 EV 186
EV
Sbjct: 207 EV 208
Score = 56.8 bits (131), Expect = 6e-08
Identities = 43/172 (25%), Positives = 73/172 (42%), Gaps = 8/172 (4%)
Query: 13 CQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLGK 72
C GNP P + W +R+ + + + G+ L+I V ED G Y C A N LG
Sbjct: 142 CTTMGNPKPSVSWIKGDSPLRENSRI-AVLESGS--LRIHNVQKEDAGQYRCVAKNSLGT 198
Query: 73 AKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKD 132
A S + ++ P + V G VT C G P P +W ++
Sbjct: 199 AYSKVVKLEVEEESEPEQDTKVFARILRAPESHNVTFGSFVTLHCTATGIPVPTITWIEN 258
Query: 133 GSIITP-SARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
G+ ++ S + +VK++ R+ ++ I G+Y N+ G ++A+
Sbjct: 259 GNAVSSGSIQESVKDRVIDSRL----QLFITKPGLYTCIATNKHGEKFSTAK 306
Score = 32.7 bits (71), Expect = 1.0
Identities = 21/72 (29%), Positives = 28/72 (38%), Gaps = 2/72 (2%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G V C TG P P I W + + S D ++ Q+ G YTC
Sbjct: 236 GSFVTLHCTATGIPVPTITWIENGNAV-SSGSIQESVKDRVIDSRL-QLFITKPGLYTCI 293
Query: 66 ASNCLGKAKSNA 77
A+N G+ S A
Sbjct: 294 ATNKHGEKFSTA 305
>AL513328-2|CAI17350.1| 867|Homo sapiens muscle, skeletal, receptor
tyrosine kinase protein.
Length = 867
Score = 71.7 bits (168), Expect = 2e-12
Identities = 58/182 (31%), Positives = 75/182 (41%), Gaps = 18/182 (9%)
Query: 7 DTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEA 66
+ F C V P P+I W +I+ D S + L I V D+G Y C A
Sbjct: 43 EVATFMCAVESYPQPEISWTRNKILIK-LFDTRYSIRENGQLLTILSVEDSDDGIYCCTA 101
Query: 67 SNCLGKA-KSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
+N +G A +S L V +M P P N + EG C GNP P
Sbjct: 102 NNGVGGAVESCGALQV-----------KMKPKITRPPINVKIIEGLKAVLPCTTMGNPKP 150
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEAS-ARL 184
SW K S + ++RI V E L I V ED G YR +N LG A + +L
Sbjct: 151 SVSWIKGDSPLRENSRIAVLESGS----LRIHNVQKEDAGQYRCVAKNSLGTAYSKVVKL 206
Query: 185 EV 186
EV
Sbjct: 207 EV 208
Score = 50.0 bits (114), Expect = 6e-06
Identities = 47/173 (27%), Positives = 75/173 (43%), Gaps = 20/173 (11%)
Query: 13 CQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLGK 72
C GNP P + W +R+ + + + G+ L+I V ED G Y C A N LG
Sbjct: 142 CTTMGNPKPSVSWIKGDSPLRENSRI-AVLESGS--LRIHNVQKEDAGQYRCVAKNSLGT 198
Query: 73 AKSNAC-LVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDK 131
A S L V R+ AP + F G VT C G P P +W +
Sbjct: 199 AYSKVVKLEVEVFARILR-----APESHNVTF------GSFVTLHCTATGIPVPTITWIE 247
Query: 132 DGSIITP-SARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
+G+ ++ S + +VK++ R+ ++ I G+Y N+ G ++A+
Sbjct: 248 NGNAVSSGSIQESVKDRVIDSRL----QLFITKPGLYTCIATNKHGEKFSTAK 296
Score = 32.7 bits (71), Expect = 1.0
Identities = 21/72 (29%), Positives = 28/72 (38%), Gaps = 2/72 (2%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G V C TG P P I W + + S D ++ Q+ G YTC
Sbjct: 226 GSFVTLHCTATGIPVPTITWIENGNAV-SSGSIQESVKDRVIDSRL-QLFITKPGLYTCI 283
Query: 66 ASNCLGKAKSNA 77
A+N G+ S A
Sbjct: 284 ATNKHGEKFSTA 295
>AL513328-1|CAI17349.1| 875|Homo sapiens muscle, skeletal, receptor
tyrosine kinase protein.
Length = 875
Score = 71.7 bits (168), Expect = 2e-12
Identities = 58/182 (31%), Positives = 75/182 (41%), Gaps = 18/182 (9%)
Query: 7 DTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEA 66
+ F C V P P+I W +I+ D S + L I V D+G Y C A
Sbjct: 43 EVATFMCAVESYPQPEISWTRNKILIK-LFDTRYSIRENGQLLTILSVEDSDDGIYCCTA 101
Query: 67 SNCLGKA-KSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
+N +G A +S L V +M P P N + EG C GNP P
Sbjct: 102 NNGVGGAVESCGALQV-----------KMKPKITRPPINVKIIEGLKAVLPCTTMGNPKP 150
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEAS-ARL 184
SW K S + ++RI V E L I V ED G YR +N LG A + +L
Sbjct: 151 SVSWIKGDSPLRENSRIAVLESGS----LRIHNVQKEDAGQYRCVAKNSLGTAYSKVVKL 206
Query: 185 EV 186
EV
Sbjct: 207 EV 208
Score = 50.0 bits (114), Expect = 6e-06
Identities = 47/173 (27%), Positives = 75/173 (43%), Gaps = 20/173 (11%)
Query: 13 CQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLGK 72
C GNP P + W +R+ + + + G+ L+I V ED G Y C A N LG
Sbjct: 142 CTTMGNPKPSVSWIKGDSPLRENSRI-AVLESGS--LRIHNVQKEDAGQYRCVAKNSLGT 198
Query: 73 AKSNAC-LVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDK 131
A S L V R+ AP + F G VT C G P P +W +
Sbjct: 199 AYSKVVKLEVEVFARILR-----APESHNVTF------GSFVTLHCTATGIPVPTITWIE 247
Query: 132 DGSIITP-SARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
+G+ ++ S + +VK++ R+ ++ I G+Y N+ G ++A+
Sbjct: 248 NGNAVSSGSIQESVKDRVIDSRL----QLFITKPGLYTCIATNKHGEKFSTAK 296
Score = 32.7 bits (71), Expect = 1.0
Identities = 21/72 (29%), Positives = 28/72 (38%), Gaps = 2/72 (2%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G V C TG P P I W + + S D ++ Q+ G YTC
Sbjct: 226 GSFVTLHCTATGIPVPTITWIENGNAV-SSGSIQESVKDRVIDSRL-QLFITKPGLYTCI 283
Query: 66 ASNCLGKAKSNA 77
A+N G+ S A
Sbjct: 284 ATNKHGEKFSTA 295
>AL157881-3|CAH69978.1| 867|Homo sapiens muscle, skeletal, receptor
tyrosine kinase protein.
Length = 867
Score = 71.7 bits (168), Expect = 2e-12
Identities = 58/182 (31%), Positives = 75/182 (41%), Gaps = 18/182 (9%)
Query: 7 DTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEA 66
+ F C V P P+I W +I+ D S + L I V D+G Y C A
Sbjct: 43 EVATFMCAVESYPQPEISWTRNKILIK-LFDTRYSIRENGQLLTILSVEDSDDGIYCCTA 101
Query: 67 SNCLGKA-KSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
+N +G A +S L V +M P P N + EG C GNP P
Sbjct: 102 NNGVGGAVESCGALQV-----------KMKPKITRPPINVKIIEGLKAVLPCTTMGNPKP 150
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEAS-ARL 184
SW K S + ++RI V E L I V ED G YR +N LG A + +L
Sbjct: 151 SVSWIKGDSPLRENSRIAVLESGS----LRIHNVQKEDAGQYRCVAKNSLGTAYSKVVKL 206
Query: 185 EV 186
EV
Sbjct: 207 EV 208
Score = 50.0 bits (114), Expect = 6e-06
Identities = 47/173 (27%), Positives = 75/173 (43%), Gaps = 20/173 (11%)
Query: 13 CQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLGK 72
C GNP P + W +R+ + + + G+ L+I V ED G Y C A N LG
Sbjct: 142 CTTMGNPKPSVSWIKGDSPLRENSRI-AVLESGS--LRIHNVQKEDAGQYRCVAKNSLGT 198
Query: 73 AKSNAC-LVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDK 131
A S L V R+ AP + F G VT C G P P +W +
Sbjct: 199 AYSKVVKLEVEVFARILR-----APESHNVTF------GSFVTLHCTATGIPVPTITWIE 247
Query: 132 DGSIITP-SARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
+G+ ++ S + +VK++ R+ ++ I G+Y N+ G ++A+
Sbjct: 248 NGNAVSSGSIQESVKDRVIDSRL----QLFITKPGLYTCIATNKHGEKFSTAK 296
Score = 32.7 bits (71), Expect = 1.0
Identities = 21/72 (29%), Positives = 28/72 (38%), Gaps = 2/72 (2%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G V C TG P P I W + + S D ++ Q+ G YTC
Sbjct: 226 GSFVTLHCTATGIPVPTITWIENGNAV-SSGSIQESVKDRVIDSRL-QLFITKPGLYTCI 283
Query: 66 ASNCLGKAKSNA 77
A+N G+ S A
Sbjct: 284 ATNKHGEKFSTA 295
>AL157881-2|CAH69977.1| 875|Homo sapiens muscle, skeletal, receptor
tyrosine kinase protein.
Length = 875
Score = 71.7 bits (168), Expect = 2e-12
Identities = 58/182 (31%), Positives = 75/182 (41%), Gaps = 18/182 (9%)
Query: 7 DTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEA 66
+ F C V P P+I W +I+ D S + L I V D+G Y C A
Sbjct: 43 EVATFMCAVESYPQPEISWTRNKILIK-LFDTRYSIRENGQLLTILSVEDSDDGIYCCTA 101
Query: 67 SNCLGKA-KSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
+N +G A +S L V +M P P N + EG C GNP P
Sbjct: 102 NNGVGGAVESCGALQV-----------KMKPKITRPPINVKIIEGLKAVLPCTTMGNPKP 150
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEAS-ARL 184
SW K S + ++RI V E L I V ED G YR +N LG A + +L
Sbjct: 151 SVSWIKGDSPLRENSRIAVLESGS----LRIHNVQKEDAGQYRCVAKNSLGTAYSKVVKL 206
Query: 185 EV 186
EV
Sbjct: 207 EV 208
Score = 50.0 bits (114), Expect = 6e-06
Identities = 47/173 (27%), Positives = 75/173 (43%), Gaps = 20/173 (11%)
Query: 13 CQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLGK 72
C GNP P + W +R+ + + + G+ L+I V ED G Y C A N LG
Sbjct: 142 CTTMGNPKPSVSWIKGDSPLRENSRI-AVLESGS--LRIHNVQKEDAGQYRCVAKNSLGT 198
Query: 73 AKSNAC-LVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDK 131
A S L V R+ AP + F G VT C G P P +W +
Sbjct: 199 AYSKVVKLEVEVFARILR-----APESHNVTF------GSFVTLHCTATGIPVPTITWIE 247
Query: 132 DGSIITP-SARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
+G+ ++ S + +VK++ R+ ++ I G+Y N+ G ++A+
Sbjct: 248 NGNAVSSGSIQESVKDRVIDSRL----QLFITKPGLYTCIATNKHGEKFSTAK 296
Score = 32.7 bits (71), Expect = 1.0
Identities = 21/72 (29%), Positives = 28/72 (38%), Gaps = 2/72 (2%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G V C TG P P I W + + S D ++ Q+ G YTC
Sbjct: 226 GSFVTLHCTATGIPVPTITWIENGNAV-SSGSIQESVKDRVIDSRL-QLFITKPGLYTCI 283
Query: 66 ASNCLGKAKSNA 77
A+N G+ S A
Sbjct: 284 ATNKHGEKFSTA 295
>AF006464-1|AAB63044.1| 869|Homo sapiens muscle specific tyrosine
kinase receptor protein.
Length = 869
Score = 71.7 bits (168), Expect = 2e-12
Identities = 58/182 (31%), Positives = 75/182 (41%), Gaps = 18/182 (9%)
Query: 7 DTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEA 66
+ F C V P P+I W +I+ D S + L I V D+G Y C A
Sbjct: 43 EVATFMCAVESYPQPEISWTRNKILIK-LFDTRYSIRENGQLLTILSVEDSDDGIYCCTA 101
Query: 67 SNCLGKA-KSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
+N +G A +S L V +M P P N + EG C GNP P
Sbjct: 102 NNGVGGAVESCGALQV-----------KMKPKITRPPINVKIIEGLKAVLPCTTMGNPKP 150
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEAS-ARL 184
SW K S + ++RI V E L I V ED G YR +N LG A + +L
Sbjct: 151 SVSWIKGDSPLRENSRIAVLESGS----LRIHNVQKEDAGQYRCVAKNSLGTAYSKVVKL 206
Query: 185 EV 186
EV
Sbjct: 207 EV 208
Score = 50.0 bits (114), Expect = 6e-06
Identities = 47/173 (27%), Positives = 75/173 (43%), Gaps = 20/173 (11%)
Query: 13 CQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLGK 72
C GNP P + W +R+ + + + G+ L+I V ED G Y C A N LG
Sbjct: 142 CTTMGNPKPSVSWIKGDSPLRENSRI-AVLESGS--LRIHNVQKEDAGQYRCVAKNSLGT 198
Query: 73 AKSNAC-LVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDK 131
A S L V R+ AP + F G VT C G P P +W +
Sbjct: 199 AYSKVVKLEVEVFARILR-----APESHNVTF------GSFVTLHCTATGIPVPTITWIE 247
Query: 132 DGSIITP-SARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
+G+ ++ S + +VK++ R+ ++ I G+Y N+ G ++A+
Sbjct: 248 NGNAVSSGSIQESVKDRVIDSRL----QLFITKPGLYTCIATNKHGEKFSTAK 296
Score = 32.7 bits (71), Expect = 1.0
Identities = 21/72 (29%), Positives = 28/72 (38%), Gaps = 2/72 (2%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G V C TG P P I W + + S D ++ Q+ G YTC
Sbjct: 226 GSFVTLHCTATGIPVPTITWIENGNAV-SSGSIQESVKDRVIDSRL-QLFITKPGLYTCI 283
Query: 66 ASNCLGKAKSNA 77
A+N G+ S A
Sbjct: 284 ATNKHGEKFSTA 295
>AF004841-1|AAC34901.2| 1264|Homo sapiens CDO protein.
Length = 1264
Score = 71.7 bits (168), Expect = 2e-12
Identities = 49/159 (30%), Positives = 69/159 (43%), Gaps = 11/159 (6%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G TV F C V GNP P+ WFH A+ I A ++ + LKI VT ED G Y C
Sbjct: 326 GATVHFTCDVHGNPAPNCTWFHNAQPIHPSARHLTAGNG----LKISGVTVEDVGMYQCV 381
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A N +G S L + + G P T P + V +G+ VT C G P P
Sbjct: 382 ADNGIGFMHSTGRL------EIENDG-GFKPVIITAPVSAKVADGDFVTLSCNASGLPVP 434
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDV 164
W +IT ++ K ++ + +++E V
Sbjct: 435 VIRWYDSHGLITSHPSQVLRSKSRKSQLSRPEGLNLEPV 473
Score = 70.9 bits (166), Expect = 3e-12
Identities = 53/183 (28%), Positives = 79/183 (43%), Gaps = 19/183 (10%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
V EC V+G P P + W + I +++ Y + L V D G Y+C A N
Sbjct: 239 VTLECVVSGVPAPQVYWLKDGQDIAPGSNWRRLY----SHLATDSVDPADSGNYSCMAGN 294
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G + +V S G Q +++V G V F C V GNP+P +
Sbjct: 295 KSGDVEYVTYMVNVLEHASISKGLQ----------DQIVSLGATVHFTCDVHGNPAPNCT 344
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVIT 188
W + I PSAR L+I V++EDVG+Y+ +N +G ++ RLE+
Sbjct: 345 WFHNAQPIHPSARHLTAGNG-----LKISGVTVEDVGMYQCVADNGIGFMHSTGRLEIEN 399
Query: 189 RSG 191
G
Sbjct: 400 DGG 402
Score = 39.1 bits (87), Expect = 0.012
Identities = 32/100 (32%), Positives = 45/100 (45%), Gaps = 23/100 (23%)
Query: 5 DGDTVEFECQVTGNPDPDIRWF--------HYAEVIRDCA-----------DFESSY--- 42
DGD V C +G P P IRW+ H ++V+R + + E Y
Sbjct: 418 DGDFVTLSCNASGLPVPVIRWYDSHGLITSHPSQVLRSKSRKSQLSRPEGLNLEPVYFVL 477
Query: 43 -DDGTARLKIKQVTAEDEGTYTCEASNCLGKAKSNACLVV 81
G + L I+ VT E G Y CEA+N G ++ A L+V
Sbjct: 478 SQAGASSLHIQAVTQEHAGKYICEAANEHGTTQAEASLMV 517
>AK128020-1|BAC87234.1| 595|Homo sapiens ursor. protein.
Length = 595
Score = 71.3 bits (167), Expect = 2e-12
Identities = 50/174 (28%), Positives = 70/174 (40%), Gaps = 9/174 (5%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G C +G P P I W + + +GT L I Q +A+D G Y C
Sbjct: 252 EGVPASLPCVASGVPAPTITWTKETNALTSRGPHYNVSKEGT--LLIAQPSAQDAGAYVC 309
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
A+N +G + L V R+ G + A P + GE VT C KG+P
Sbjct: 310 TATNTVGFSSQEMRLSVNTKPRIHMNGSRNADV----PLQVTAKAGEEVTLDCEAKGSPP 365
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRA 178
P +W KD + P IT + L + +V + D G Y T N G A
Sbjct: 366 PLVTWTKDSRPVPP---ITNRYGLLPSGSLRLAQVQVGDSGHYECTASNPAGSA 416
Score = 55.2 bits (127), Expect = 2e-07
Identities = 53/186 (28%), Positives = 71/186 (38%), Gaps = 18/186 (9%)
Query: 6 GDTVEFECQVTGNPDPDIRWFH---YAEVIRDCADFES-SYDDGTARLKIKQVTAEDEGT 61
G + C+ TG P P + W +R A S S + L + V ED+
Sbjct: 63 GRSALLACRATGRPPPTVTWRRGDGQPLGLRLGAGRGSRSRQPDSGVLFFESVAPEDQAP 122
Query: 62 YTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAV-K 120
Y CEA N GK ++ A L+V T APT V EG+ V+ C V
Sbjct: 123 YVCEARNVFGKVQAEARLIV--TGHAPPQIASSAPTVR-------VLEGQPVSLPCIVLA 173
Query: 121 GNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEA 180
G P P W KDG + P +R +++ L +D E G Y N G
Sbjct: 174 GRPLPERHWLKDGRPLPPGSRHSIRADGS----LHLDRALQEHAGRYSCVATNTAGSQHR 229
Query: 181 SARLEV 186
L V
Sbjct: 230 DVELVV 235
Score = 53.6 bits (123), Expect = 5e-07
Identities = 42/144 (29%), Positives = 59/144 (40%), Gaps = 14/144 (9%)
Query: 46 TARLKIKQVTAEDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNK 105
+ +L+I D GTYTC A N LG A + L V H AP P +
Sbjct: 10 SGKLRIPAAQERDAGTYTCRAVNELGDASAEIQLAVGH-----------APQLTELPRDV 58
Query: 106 VVEEGENVTFKCAVKGNPSPWASWDK-DGSI--ITPSARITVKEKEEIMRILEIDEVSIE 162
VE G + C G P P +W + DG + A + ++ +L + V+ E
Sbjct: 59 TVELGRSALLACRATGRPPPTVTWRRGDGQPLGLRLGAGRGSRSRQPDSGVLFFESVAPE 118
Query: 163 DVGIYRITVENELGRAEASARLEV 186
D Y N G+ +A ARL V
Sbjct: 119 DQAPYVCEARNVFGKVQAEARLIV 142
Score = 53.2 bits (122), Expect = 7e-07
Identities = 50/195 (25%), Positives = 74/195 (37%), Gaps = 18/195 (9%)
Query: 5 DGDTVEFECQV-TGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYT 63
+G V C V G P P+ W + S DG+ L + + E G Y+
Sbjct: 161 EGQPVSLPCIVLAGRPLPERHWLKDGRPLPP-GSRHSIRADGS--LHLDRALQEHAGRYS 217
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
C A+N G + LVV Q+ P + + + EG + C G P
Sbjct: 218 CVATNTAGSQHRDVELVV-----------QVPPRIHPTATHHITNEGVPASLPCVASGVP 266
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
+P +W K+ + +T KE L I + S +D G Y T N +G + R
Sbjct: 267 APTITWTKETNALTSRGPHYNVSKE---GTLLIAQPSAQDAGAYVCTATNTVGFSSQEMR 323
Query: 184 LEVITRSGKFYGGLR 198
L V T+ G R
Sbjct: 324 LSVNTKPRIHMNGSR 338
Score = 39.1 bits (87), Expect = 0.012
Identities = 23/76 (30%), Positives = 32/76 (42%), Gaps = 2/76 (2%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+ V +C+ G+P P + W + + + G+ RL QV D G Y C
Sbjct: 351 GEEVTLDCEAKGSPPPLVTWTKDSRPVPPITNRYGLLPSGSLRLA--QVQVGDSGHYECT 408
Query: 66 ASNCLGKAKSNACLVV 81
ASN G A L V
Sbjct: 409 ASNPAGSASHRYVLGV 424
>AB208869-1|BAD92106.1| 1478|Homo sapiens protein tyrosine
phosphatase, receptor type, D isoform 4 precursor
variant protein.
Length = 1478
Score = 70.9 bits (166), Expect = 3e-12
Identities = 58/189 (30%), Positives = 81/189 (42%), Gaps = 12/189 (6%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTAR-LKIKQV-TAEDEGTYT 63
G F CQ TG+P P I W + + + +DDG+ L+I+ + T DE Y
Sbjct: 14 GGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYE 73
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
C ASN +G+ + L V ++ + PT P KVVE T CA GNP
Sbjct: 74 CVASNNVGEISVSTRLTVLREDQIP----RGFPTIDMGPQLKVVERTRTATMLCAASGNP 129
Query: 124 SPWASWDKDG-SIITPSARITVKEKEE----IMRILEIDEVSIEDVGIYRITVENELG-R 177
P +W KD + T + +K+ I L+I++ D G Y N G R
Sbjct: 130 DPEITWFKDFLPVDTSNNNGRIKQLRSGGTPIRGALQIEQSEESDQGKYECVATNSAGTR 189
Query: 178 AEASARLEV 186
A A L V
Sbjct: 190 YSAPANLYV 198
Score = 62.9 bits (146), Expect = 8e-10
Identities = 50/186 (26%), Positives = 78/186 (41%), Gaps = 18/186 (9%)
Query: 8 TVEFECQVTGNPDPDIRWFHY---AEVIRDCADFESSYDDGT---ARLKIKQVTAEDEGT 61
T C +GNPDP+I WF + + + GT L+I+Q D+G
Sbjct: 118 TATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSGGTPIRGALQIEQSEESDQGK 177
Query: 62 YTCEASNCLG-KAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVK 120
Y C A+N G + + A L V R + R++ P F P N + G +V C
Sbjct: 178 YECVATNSAGTRYSAPANLYVRELREV----RRVPPRFSIPPTNHEIMPGGSVNITCVAV 233
Query: 121 GNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEA 180
G+P P+ W +TP + + +LE+++V Y + LG EA
Sbjct: 234 GSPMPYVKWMLGAEDLTPEDDMPIGR-----NVLELNDV--RQSANYTCVAMSTLGVIEA 286
Query: 181 SARLEV 186
A++ V
Sbjct: 287 IAQITV 292
Score = 38.3 bits (85), Expect = 0.021
Identities = 28/120 (23%), Positives = 47/120 (39%), Gaps = 2/120 (1%)
Query: 98 FYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEID 157
F P ++ G +F C G+P P W+K G ++ ++ + +L I
Sbjct: 2 FTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQ 61
Query: 158 EV-SIEDVGIYRITVENELGRAEASARLEVITRSGKFYGGLRAYSASPRKCLSYRRRPST 216
+ + D IY N +G S RL V+ R + G P+ + R R +T
Sbjct: 62 PLRTPRDEAIYECVASNNVGEISVSTRLTVL-REDQIPRGFPTIDMGPQLKVVERTRTAT 120
Score = 29.5 bits (63), Expect = 9.6
Identities = 21/76 (27%), Positives = 32/76 (42%), Gaps = 6/76 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G +V C G+P P ++W AE + E G L++ V YTC
Sbjct: 223 GGSVNITCVAVGSPMPYVKWMLGAEDLTP----EDDMPIGRNVLELNDV--RQSANYTCV 276
Query: 66 ASNCLGKAKSNACLVV 81
A + LG ++ A + V
Sbjct: 277 AMSTLGVIEAIAQITV 292
>BC126171-1|AAI26172.1| 1119|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 3 protein.
Length = 1119
Score = 70.5 bits (165), Expect = 4e-12
Identities = 46/146 (31%), Positives = 71/146 (48%), Gaps = 18/146 (12%)
Query: 46 TARLKIKQVTAEDEGTYTCEASNCLGKAKS-NACLVVYHTRRLSSPGRQMAPTFYTYPFN 104
T L++++V EG Y C SN G + S A L V M P+F P +
Sbjct: 563 TTILRLREVEFASEGKYQCVISNHFGSSYSVKAKLTV-----------NMLPSFTKTPMD 611
Query: 105 KVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSA---RITVKEKEEIMRILEIDEVSI 161
+ G +CA G+P+P +W KDG P+A R+ V ++++ I+ +V I
Sbjct: 612 LTIRAGAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFFIV---DVKI 668
Query: 162 EDVGIYRITVENELGRAEASARLEVI 187
ED+G+Y T +N G A+A L V+
Sbjct: 669 EDIGVYSCTAQNSAGSISANATLTVL 694
Score = 67.3 bits (157), Expect = 4e-11
Identities = 51/185 (27%), Positives = 73/185 (39%), Gaps = 19/185 (10%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSY---DDGTARLKIKQVTAEDEGTY 62
G EC G+P P I W A + +D I V ED G Y
Sbjct: 617 GAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDV--FFIVDVKIEDIGVY 674
Query: 63 TCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGN 122
+C A N G +NA L V T P+F ++ V +GE +C G+
Sbjct: 675 SCTAQNSAGSISANATLTVLET-----------PSFLRPLLDRTVTKGETAVLQCIAGGS 723
Query: 123 PSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASA 182
P P +W KD S + + R +++ I++ D + D G Y + N LG +
Sbjct: 724 PPPKLNWTKDDSPLVVTERHFFAAGNQLLIIVDSD---VSDAGKYTCEMSNTLGTERGNV 780
Query: 183 RLEVI 187
RL VI
Sbjct: 781 RLSVI 785
Score = 42.3 bits (95), Expect = 0.001
Identities = 28/92 (30%), Positives = 37/92 (40%), Gaps = 3/92 (3%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+T +C G+P P + W + + G L I D G YTCE
Sbjct: 711 GETAVLQCIAGGSPPPKLNWTKDDSPL--VVTERHFFAAGNQLLIIVDSDVSDAGKYTCE 768
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPT 97
SN LG + N L V T SP + AP+
Sbjct: 769 MSNTLGTERGNVRLSVIPTPTCDSP-QMTAPS 799
>BC126169-1|AAI26170.1| 1119|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 3 protein.
Length = 1119
Score = 70.5 bits (165), Expect = 4e-12
Identities = 46/146 (31%), Positives = 71/146 (48%), Gaps = 18/146 (12%)
Query: 46 TARLKIKQVTAEDEGTYTCEASNCLGKAKS-NACLVVYHTRRLSSPGRQMAPTFYTYPFN 104
T L++++V EG Y C SN G + S A L V M P+F P +
Sbjct: 563 TTILRLREVEFASEGKYQCVISNHFGSSYSVKAKLTV-----------NMLPSFTKTPMD 611
Query: 105 KVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSA---RITVKEKEEIMRILEIDEVSI 161
+ G +CA G+P+P +W KDG P+A R+ V ++++ I+ +V I
Sbjct: 612 LTIRAGAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFFIV---DVKI 668
Query: 162 EDVGIYRITVENELGRAEASARLEVI 187
ED+G+Y T +N G A+A L V+
Sbjct: 669 EDIGVYSCTAQNSAGSISANATLTVL 694
Score = 67.3 bits (157), Expect = 4e-11
Identities = 51/185 (27%), Positives = 73/185 (39%), Gaps = 19/185 (10%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSY---DDGTARLKIKQVTAEDEGTY 62
G EC G+P P I W A + +D I V ED G Y
Sbjct: 617 GAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDV--FFIVDVKIEDIGVY 674
Query: 63 TCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGN 122
+C A N G +NA L V T P+F ++ V +GE +C G+
Sbjct: 675 SCTAQNSAGSISANATLTVLET-----------PSFLRPLLDRTVTKGETAVLQCIAGGS 723
Query: 123 PSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASA 182
P P +W KD S + + R +++ I++ D + D G Y + N LG +
Sbjct: 724 PPPKLNWTKDDSPLVVTERHFFAAGNQLLIIVDSD---VSDAGKYTCEMSNTLGTERGNV 780
Query: 183 RLEVI 187
RL VI
Sbjct: 781 RLSVI 785
Score = 42.3 bits (95), Expect = 0.001
Identities = 28/92 (30%), Positives = 37/92 (40%), Gaps = 3/92 (3%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+T +C G+P P + W + + G L I D G YTCE
Sbjct: 711 GETAVLQCIAGGSPPPKLNWTKDDSPL--VVTERHFFAAGNQLLIIVDSDVSDAGKYTCE 768
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPT 97
SN LG + N L V T SP + AP+
Sbjct: 769 MSNTLGTERGNVRLSVIPTPTCDSP-QMTAPS 799
>AY505340-1|AAR98629.1| 1119|Homo sapiens leucine-rich and
immunoglobulin-like domains 3 protein.
Length = 1119
Score = 70.5 bits (165), Expect = 4e-12
Identities = 46/146 (31%), Positives = 71/146 (48%), Gaps = 18/146 (12%)
Query: 46 TARLKIKQVTAEDEGTYTCEASNCLGKAKS-NACLVVYHTRRLSSPGRQMAPTFYTYPFN 104
T L++++V EG Y C SN G + S A L V M P+F P +
Sbjct: 563 TTILRLREVEFASEGKYQCVISNHFGSSYSVKAKLTV-----------NMLPSFTKTPMD 611
Query: 105 KVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSA---RITVKEKEEIMRILEIDEVSI 161
+ G +CA G+P+P +W KDG P+A R+ V ++++ I+ +V I
Sbjct: 612 LTIRAGAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFFIV---DVKI 668
Query: 162 EDVGIYRITVENELGRAEASARLEVI 187
ED+G+Y T +N G A+A L V+
Sbjct: 669 EDIGVYSCTAQNSAGSISANATLTVL 694
Score = 67.3 bits (157), Expect = 4e-11
Identities = 51/185 (27%), Positives = 73/185 (39%), Gaps = 19/185 (10%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSY---DDGTARLKIKQVTAEDEGTY 62
G EC G+P P I W A + +D I V ED G Y
Sbjct: 617 GAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDV--FFIVDVKIEDIGVY 674
Query: 63 TCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGN 122
+C A N G +NA L V T P+F ++ V +GE +C G+
Sbjct: 675 SCTAQNSAGSISANATLTVLET-----------PSFLRPLLDRTVTKGETAVLQCIAGGS 723
Query: 123 PSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASA 182
P P +W KD S + + R +++ I++ D + D G Y + N LG +
Sbjct: 724 PPPKLNWTKDDSPLVVTERHFFAAGNQLLIIVDSD---VSDAGKYTCEMSNTLGTERGNV 780
Query: 183 RLEVI 187
RL VI
Sbjct: 781 RLSVI 785
Score = 42.3 bits (95), Expect = 0.001
Identities = 28/92 (30%), Positives = 37/92 (40%), Gaps = 3/92 (3%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+T +C G+P P + W + + G L I D G YTCE
Sbjct: 711 GETAVLQCIAGGSPPPKLNWTKDDSPL--VVTERHFFAAGNQLLIIVDSDVSDAGKYTCE 768
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPT 97
SN LG + N L V T SP + AP+
Sbjct: 769 MSNTLGTERGNVRLSVIPTPTCDSP-QMTAPS 799
>AY358295-1|AAQ88662.1| 1059|Homo sapiens SAPS287 protein.
Length = 1059
Score = 70.5 bits (165), Expect = 4e-12
Identities = 46/146 (31%), Positives = 71/146 (48%), Gaps = 18/146 (12%)
Query: 46 TARLKIKQVTAEDEGTYTCEASNCLGKAKS-NACLVVYHTRRLSSPGRQMAPTFYTYPFN 104
T L++++V EG Y C SN G + S A L V M P+F P +
Sbjct: 503 TTILRLREVEFASEGKYQCVISNHFGSSYSVKAKLTV-----------NMLPSFTKTPMD 551
Query: 105 KVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSA---RITVKEKEEIMRILEIDEVSI 161
+ G +CA G+P+P +W KDG P+A R+ V ++++ I+ +V I
Sbjct: 552 LTIRAGAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFFIV---DVKI 608
Query: 162 EDVGIYRITVENELGRAEASARLEVI 187
ED+G+Y T +N G A+A L V+
Sbjct: 609 EDIGVYSCTAQNSAGSISANATLTVL 634
Score = 67.3 bits (157), Expect = 4e-11
Identities = 51/185 (27%), Positives = 73/185 (39%), Gaps = 19/185 (10%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSY---DDGTARLKIKQVTAEDEGTY 62
G EC G+P P I W A + +D I V ED G Y
Sbjct: 557 GAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDV--FFIVDVKIEDIGVY 614
Query: 63 TCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGN 122
+C A N G +NA L V T P+F ++ V +GE +C G+
Sbjct: 615 SCTAQNSAGSISANATLTVLET-----------PSFLRPLLDRTVTKGETAVLQCIAGGS 663
Query: 123 PSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASA 182
P P +W KD S + + R +++ I++ D + D G Y + N LG +
Sbjct: 664 PPPKLNWTKDDSPLVVTERHFFAAGNQLLIIVDSD---VSDAGKYTCEMSNTLGTERGNV 720
Query: 183 RLEVI 187
RL VI
Sbjct: 721 RLSVI 725
Score = 42.3 bits (95), Expect = 0.001
Identities = 28/92 (30%), Positives = 37/92 (40%), Gaps = 3/92 (3%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+T +C G+P P + W + + G L I D G YTCE
Sbjct: 651 GETAVLQCIAGGSPPPKLNWTKDDSPL--VVTERHFFAAGNQLLIIVDSDVSDAGKYTCE 708
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPT 97
SN LG + N L V T SP + AP+
Sbjct: 709 MSNTLGTERGNVRLSVIPTPTCDSP-QMTAPS 739
>AY358288-1|AAQ88655.1| 1119|Homo sapiens SAPS287 protein.
Length = 1119
Score = 70.5 bits (165), Expect = 4e-12
Identities = 46/146 (31%), Positives = 71/146 (48%), Gaps = 18/146 (12%)
Query: 46 TARLKIKQVTAEDEGTYTCEASNCLGKAKS-NACLVVYHTRRLSSPGRQMAPTFYTYPFN 104
T L++++V EG Y C SN G + S A L V M P+F P +
Sbjct: 563 TTILRLREVEFASEGKYQCVISNHFGSSYSVKAKLTV-----------NMLPSFTKTPMD 611
Query: 105 KVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSA---RITVKEKEEIMRILEIDEVSI 161
+ G +CA G+P+P +W KDG P+A R+ V ++++ I+ +V I
Sbjct: 612 LTIRAGAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFFIV---DVKI 668
Query: 162 EDVGIYRITVENELGRAEASARLEVI 187
ED+G+Y T +N G A+A L V+
Sbjct: 669 EDIGVYSCTAQNSAGSISANATLTVL 694
Score = 67.3 bits (157), Expect = 4e-11
Identities = 51/185 (27%), Positives = 73/185 (39%), Gaps = 19/185 (10%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSY---DDGTARLKIKQVTAEDEGTY 62
G EC G+P P I W A + +D I V ED G Y
Sbjct: 617 GAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDV--FFIVDVKIEDIGVY 674
Query: 63 TCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGN 122
+C A N G +NA L V T P+F ++ V +GE +C G+
Sbjct: 675 SCTAQNSAGSISANATLTVLET-----------PSFLRPLLDRTVTKGETAVLQCIAGGS 723
Query: 123 PSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASA 182
P P +W KD S + + R +++ I++ D + D G Y + N LG +
Sbjct: 724 PPPKLNWTKDDSPLVVTERHFFAAGNQLLIIVDSD---VSDAGKYTCEMSNTLGTERGNV 780
Query: 183 RLEVI 187
RL VI
Sbjct: 781 RLSVI 785
Score = 42.3 bits (95), Expect = 0.001
Identities = 28/92 (30%), Positives = 37/92 (40%), Gaps = 3/92 (3%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+T +C G+P P + W + + G L I D G YTCE
Sbjct: 711 GETAVLQCIAGGSPPPKLNWTKDDSPL--VVTERHFFAAGNQLLIIVDSDVSDAGKYTCE 768
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPT 97
SN LG + N L V T SP + AP+
Sbjct: 769 MSNTLGTERGNVRLSVIPTPTCDSP-QMTAPS 799
>AK074921-1|BAC11295.1| 697|Homo sapiens protein ( Homo sapiens
cDNA FLJ90440 fis, clone NT2RP3000921, weakly similar to
TUMOR SUPPRESSOR PROTEIN DCC PRECURSOR. ).
Length = 697
Score = 70.5 bits (165), Expect = 4e-12
Identities = 46/146 (31%), Positives = 71/146 (48%), Gaps = 18/146 (12%)
Query: 46 TARLKIKQVTAEDEGTYTCEASNCLGKAKS-NACLVVYHTRRLSSPGRQMAPTFYTYPFN 104
T L++++V EG Y C SN G + S A L V M P+F P +
Sbjct: 141 TTILRLREVEFASEGKYQCVISNHFGSSYSVKAKLTV-----------NMLPSFTKTPMD 189
Query: 105 KVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSA---RITVKEKEEIMRILEIDEVSI 161
+ G +CA G+P+P +W KDG P+A R+ V ++++ I+ +V I
Sbjct: 190 LTIRAGAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFFIV---DVKI 246
Query: 162 EDVGIYRITVENELGRAEASARLEVI 187
ED+G+Y T +N G A+A L V+
Sbjct: 247 EDIGVYSCTAQNSAGSISANATLTVL 272
Score = 67.3 bits (157), Expect = 4e-11
Identities = 51/185 (27%), Positives = 73/185 (39%), Gaps = 19/185 (10%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSY---DDGTARLKIKQVTAEDEGTY 62
G EC G+P P I W A + +D I V ED G Y
Sbjct: 195 GAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDV--FFIVDVKIEDIGVY 252
Query: 63 TCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGN 122
+C A N G +NA L V T P+F ++ V +GE +C G+
Sbjct: 253 SCTAQNSAGSISANATLTVLET-----------PSFLRPLLDRTVTKGETAVLQCIAGGS 301
Query: 123 PSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASA 182
P P +W KD S + + R +++ I++ D + D G Y + N LG +
Sbjct: 302 PPPKLNWTKDDSPLVVTERHFFAAGNQLLIIVDSD---VSDAGKYTCEMSNTLGTERGNV 358
Query: 183 RLEVI 187
RL VI
Sbjct: 359 RLSVI 363
Score = 42.3 bits (95), Expect = 0.001
Identities = 28/92 (30%), Positives = 37/92 (40%), Gaps = 3/92 (3%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+T +C G+P P + W + + G L I D G YTCE
Sbjct: 289 GETAVLQCIAGGSPPPKLNWTKDDSPL--VVTERHFFAAGNQLLIIVDSDVSDAGKYTCE 346
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPT 97
SN LG + N L V T SP + AP+
Sbjct: 347 MSNTLGTERGNVRLSVIPTPTCDSP-QMTAPS 377
>L38929-1|AAC41749.1| 1912|Homo sapiens protein tyrosine phosphatase
delta protein.
Length = 1912
Score = 70.1 bits (164), Expect = 6e-12
Identities = 60/192 (31%), Positives = 80/192 (41%), Gaps = 15/192 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTAR-LKIKQV-TAEDEGTYT 63
G F CQ TG+P P I W + + + +DDG+ L+I+ + T DE Y
Sbjct: 38 GGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYE 97
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
C ASN +G+ + L V ++ + PT P KVVE T CA GNP
Sbjct: 98 CVASNNVGEISVSTRLTVLREDQIP----RGFPTIDMGPQLKVVERTRTATMLCAASGNP 153
Query: 124 SPWASWDKDGSIITPS---ARITVKEKEE-----IMRILEIDEVSIEDVGIYRITVENEL 175
P +W KD + S RI E I L+I++ D G Y N
Sbjct: 154 DPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQSEESDQGKYECVATNSA 213
Query: 176 G-RAEASARLEV 186
G R A A L V
Sbjct: 214 GTRYSAPANLYV 225
Score = 60.1 bits (139), Expect = 6e-09
Identities = 52/189 (27%), Positives = 78/189 (41%), Gaps = 21/189 (11%)
Query: 8 TVEFECQVTGNPDPDIRWFH-YAEVIRD-----CADFESSYDDGT---ARLKIKQVTAED 58
T C +GNPDP+I WF + V S GT L+I+Q D
Sbjct: 142 TATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQSEESD 201
Query: 59 EGTYTCEASNCLG-KAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKC 117
+G Y C A+N G + + A L V R + R++ P F P N + G +V C
Sbjct: 202 QGKYECVATNSAGTRYSAPANLYVRELREV----RRVPPRFSIPPTNHEIMPGGSVNITC 257
Query: 118 AVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGR 177
G+P P+ W +TP + + +LE+++V Y + LG
Sbjct: 258 VAVGSPMPYVKWMLGAEDLTPEDDMPIGR-----NVLELNDV--RQSANYTCVAMSTLGV 310
Query: 178 AEASARLEV 186
EA A++ V
Sbjct: 311 IEAIAQITV 319
Score = 40.7 bits (91), Expect = 0.004
Identities = 29/122 (23%), Positives = 48/122 (39%), Gaps = 2/122 (1%)
Query: 96 PTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILE 155
P F P ++ G +F C G+P P W+K G ++ ++ + +L
Sbjct: 24 PRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLR 83
Query: 156 IDEV-SIEDVGIYRITVENELGRAEASARLEVITRSGKFYGGLRAYSASPRKCLSYRRRP 214
I + + D IY N +G S RL V+ R + G P+ + R R
Sbjct: 84 IQPLRTPRDEAIYECVASNNVGEISVSTRLTVL-REDQIPRGFPTIDMGPQLKVVERTRT 142
Query: 215 ST 216
+T
Sbjct: 143 AT 144
Score = 29.5 bits (63), Expect = 9.6
Identities = 21/76 (27%), Positives = 32/76 (42%), Gaps = 6/76 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G +V C G+P P ++W AE + E G L++ V YTC
Sbjct: 250 GGSVNITCVAVGSPMPYVKWMLGAEDLTP----EDDMPIGRNVLELNDV--RQSANYTCV 303
Query: 66 ASNCLGKAKSNACLVV 81
A + LG ++ A + V
Sbjct: 304 AMSTLGVIEAIAQITV 319
>BC106715-1|AAI06716.1| 1505|Homo sapiens PTPRD protein protein.
Length = 1505
Score = 70.1 bits (164), Expect = 6e-12
Identities = 60/192 (31%), Positives = 80/192 (41%), Gaps = 15/192 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTAR-LKIKQV-TAEDEGTYT 63
G F CQ TG+P P I W + + + +DDG+ L+I+ + T DE Y
Sbjct: 38 GGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYE 97
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
C ASN +G+ + L V ++ + PT P KVVE T CA GNP
Sbjct: 98 CVASNNVGEISVSTRLTVLREDQIP----RGFPTIDMGPQLKVVERTRTATMLCAASGNP 153
Query: 124 SPWASWDKDGSIITPS---ARITVKEKEE-----IMRILEIDEVSIEDVGIYRITVENEL 175
P +W KD + S RI E I L+I++ D G Y N
Sbjct: 154 DPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQSEESDQGKYECVATNSA 213
Query: 176 G-RAEASARLEV 186
G R A A L V
Sbjct: 214 GTRYSAPANLYV 225
Score = 60.1 bits (139), Expect = 6e-09
Identities = 52/189 (27%), Positives = 78/189 (41%), Gaps = 21/189 (11%)
Query: 8 TVEFECQVTGNPDPDIRWFH-YAEVIRD-----CADFESSYDDGT---ARLKIKQVTAED 58
T C +GNPDP+I WF + V S GT L+I+Q D
Sbjct: 142 TATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQSEESD 201
Query: 59 EGTYTCEASNCLG-KAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKC 117
+G Y C A+N G + + A L V R + R++ P F P N + G +V C
Sbjct: 202 QGKYECVATNSAGTRYSAPANLYVRELREV----RRVPPRFSIPPTNHEIMPGGSVNITC 257
Query: 118 AVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGR 177
G+P P+ W +TP + + +LE+++V Y + LG
Sbjct: 258 VAVGSPMPYVKWMLGAEDLTPEDDMPIGR-----NVLELNDV--RQSANYTCVAMSTLGV 310
Query: 178 AEASARLEV 186
EA A++ V
Sbjct: 311 IEAIAQITV 319
Score = 40.7 bits (91), Expect = 0.004
Identities = 29/122 (23%), Positives = 48/122 (39%), Gaps = 2/122 (1%)
Query: 96 PTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILE 155
P F P ++ G +F C G+P P W+K G ++ ++ + +L
Sbjct: 24 PRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLR 83
Query: 156 IDEV-SIEDVGIYRITVENELGRAEASARLEVITRSGKFYGGLRAYSASPRKCLSYRRRP 214
I + + D IY N +G S RL V+ R + G P+ + R R
Sbjct: 84 IQPLRTPRDEAIYECVASNNVGEISVSTRLTVL-REDQIPRGFPTIDMGPQLKVVERTRT 142
Query: 215 ST 216
+T
Sbjct: 143 AT 144
Score = 29.5 bits (63), Expect = 9.6
Identities = 21/76 (27%), Positives = 32/76 (42%), Gaps = 6/76 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G +V C G+P P ++W AE + E G L++ V YTC
Sbjct: 250 GGSVNITCVAVGSPMPYVKWMLGAEDLTP----EDDMPIGRNVLELNDV--RQSANYTCV 303
Query: 66 ASNCLGKAKSNACLVV 81
A + LG ++ A + V
Sbjct: 304 AMSTLGVIEAIAQITV 319
>BC106714-1|AAI06715.1| 1506|Homo sapiens PTPRD protein protein.
Length = 1506
Score = 70.1 bits (164), Expect = 6e-12
Identities = 60/192 (31%), Positives = 80/192 (41%), Gaps = 15/192 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTAR-LKIKQV-TAEDEGTYT 63
G F CQ TG+P P I W + + + +DDG+ L+I+ + T DE Y
Sbjct: 38 GGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYE 97
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
C ASN +G+ + L V ++ + PT P KVVE T CA GNP
Sbjct: 98 CVASNNVGEISVSTRLTVLREDQIP----RGFPTIDMGPQLKVVERTRTATMLCAASGNP 153
Query: 124 SPWASWDKDGSIITPS---ARITVKEKEE-----IMRILEIDEVSIEDVGIYRITVENEL 175
P +W KD + S RI E I L+I++ D G Y N
Sbjct: 154 DPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQSEESDQGKYECVATNSA 213
Query: 176 G-RAEASARLEV 186
G R A A L V
Sbjct: 214 GTRYSAPANLYV 225
Score = 60.1 bits (139), Expect = 6e-09
Identities = 52/189 (27%), Positives = 78/189 (41%), Gaps = 21/189 (11%)
Query: 8 TVEFECQVTGNPDPDIRWFH-YAEVIRD-----CADFESSYDDGT---ARLKIKQVTAED 58
T C +GNPDP+I WF + V S GT L+I+Q D
Sbjct: 142 TATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQSEESD 201
Query: 59 EGTYTCEASNCLG-KAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKC 117
+G Y C A+N G + + A L V R + R++ P F P N + G +V C
Sbjct: 202 QGKYECVATNSAGTRYSAPANLYVRELREV----RRVPPRFSIPPTNHEIMPGGSVNITC 257
Query: 118 AVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGR 177
G+P P+ W +TP + + +LE+++V Y + LG
Sbjct: 258 VAVGSPMPYVKWMLGAEDLTPEDDMPIGR-----NVLELNDV--RQSANYTCVAMSTLGV 310
Query: 178 AEASARLEV 186
EA A++ V
Sbjct: 311 IEAIAQITV 319
Score = 40.7 bits (91), Expect = 0.004
Identities = 29/122 (23%), Positives = 48/122 (39%), Gaps = 2/122 (1%)
Query: 96 PTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILE 155
P F P ++ G +F C G+P P W+K G ++ ++ + +L
Sbjct: 24 PRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLR 83
Query: 156 IDEV-SIEDVGIYRITVENELGRAEASARLEVITRSGKFYGGLRAYSASPRKCLSYRRRP 214
I + + D IY N +G S RL V+ R + G P+ + R R
Sbjct: 84 IQPLRTPRDEAIYECVASNNVGEISVSTRLTVL-REDQIPRGFPTIDMGPQLKVVERTRT 142
Query: 215 ST 216
+T
Sbjct: 143 AT 144
Score = 29.5 bits (63), Expect = 9.6
Identities = 21/76 (27%), Positives = 32/76 (42%), Gaps = 6/76 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G +V C G+P P ++W AE + E G L++ V YTC
Sbjct: 250 GGSVNITCVAVGSPMPYVKWMLGAEDLTP----EDDMPIGRNVLELNDV--RQSANYTCV 303
Query: 66 ASNCLGKAKSNACLVV 81
A + LG ++ A + V
Sbjct: 304 AMSTLGVIEAIAQITV 319
>BC005376-1|AAH05376.1| 498|Homo sapiens myotilin protein.
Length = 498
Score = 70.1 bits (164), Expect = 6e-12
Identities = 50/187 (26%), Positives = 83/187 (44%), Gaps = 8/187 (4%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIR-DCADFESSYDDGTARLKIKQVTAEDEGTYT 63
+G + +V+G P PD+ W+ ++ D + G L + V A D G Y
Sbjct: 263 EGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYA 322
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
C A N G+A L V + + AP F P +K V EG++V +C + P
Sbjct: 323 CVAKNRAGEATFTVQLDVL------AKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIP 376
Query: 124 SPWASWDKDGSIIT-PSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASA 182
P W ++ ++ + RI++ + L I +V+ +D G Y ++ NE G +
Sbjct: 377 PPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNT 436
Query: 183 RLEVITR 189
RL+V R
Sbjct: 437 RLDVTAR 443
Score = 54.0 bits (124), Expect = 4e-07
Identities = 36/102 (35%), Positives = 51/102 (50%), Gaps = 5/102 (4%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTAR--LKIKQVTAEDEGTY 62
+GD+V+ ECQ++ P P + W E+++ D S Y D T R L IK V +D G Y
Sbjct: 362 EGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWY 421
Query: 63 TCEASNCLGKAKSNACLVV--YHTRRLSSPGR-QMAPTFYTY 101
T A N G N L V + L +P + ++ PTF Y
Sbjct: 422 TVSAVNEAGVTTCNTRLDVTARPNQTLPAPKQLRVRPTFSKY 463
Score = 43.6 bits (98), Expect = 6e-04
Identities = 25/97 (25%), Positives = 40/97 (41%)
Query: 96 PTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILE 155
P F P N ++EG V G P+P SW +G + + E+ + L
Sbjct: 250 PRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLI 309
Query: 156 IDEVSIEDVGIYRITVENELGRAEASARLEVITRSGK 192
+ V D G Y +N G A + +L+V+ + K
Sbjct: 310 FEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHK 346
>AL590397-1|CAH73128.2| 1912|Homo sapiens protein tyrosine
phosphatase, receptor type, D protein.
Length = 1912
Score = 70.1 bits (164), Expect = 6e-12
Identities = 60/192 (31%), Positives = 80/192 (41%), Gaps = 15/192 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTAR-LKIKQV-TAEDEGTYT 63
G F CQ TG+P P I W + + + +DDG+ L+I+ + T DE Y
Sbjct: 38 GGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYE 97
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
C ASN +G+ + L V ++ + PT P KVVE T CA GNP
Sbjct: 98 CVASNNVGEISVSTRLTVLREDQIP----RGFPTIDMGPQLKVVERTRTATMLCAASGNP 153
Query: 124 SPWASWDKDGSIITPS---ARITVKEKEE-----IMRILEIDEVSIEDVGIYRITVENEL 175
P +W KD + S RI E I L+I++ D G Y N
Sbjct: 154 DPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQSEESDQGKYECVATNSA 213
Query: 176 G-RAEASARLEV 186
G R A A L V
Sbjct: 214 GTRYSAPANLYV 225
Score = 60.1 bits (139), Expect = 6e-09
Identities = 52/189 (27%), Positives = 78/189 (41%), Gaps = 21/189 (11%)
Query: 8 TVEFECQVTGNPDPDIRWFH-YAEVIRD-----CADFESSYDDGT---ARLKIKQVTAED 58
T C +GNPDP+I WF + V S GT L+I+Q D
Sbjct: 142 TATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQSEESD 201
Query: 59 EGTYTCEASNCLG-KAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKC 117
+G Y C A+N G + + A L V R + R++ P F P N + G +V C
Sbjct: 202 QGKYECVATNSAGTRYSAPANLYVRELREV----RRVPPRFSIPPTNHEIMPGGSVNITC 257
Query: 118 AVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGR 177
G+P P+ W +TP + + +LE+++V Y + LG
Sbjct: 258 VAVGSPMPYVKWMLGAEDLTPEDDMPIGR-----NVLELNDV--RQSANYTCVAMSTLGV 310
Query: 178 AEASARLEV 186
EA A++ V
Sbjct: 311 IEAIAQITV 319
Score = 40.7 bits (91), Expect = 0.004
Identities = 29/122 (23%), Positives = 48/122 (39%), Gaps = 2/122 (1%)
Query: 96 PTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILE 155
P F P ++ G +F C G+P P W+K G ++ ++ + +L
Sbjct: 24 PRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLR 83
Query: 156 IDEV-SIEDVGIYRITVENELGRAEASARLEVITRSGKFYGGLRAYSASPRKCLSYRRRP 214
I + + D IY N +G S RL V+ R + G P+ + R R
Sbjct: 84 IQPLRTPRDEAIYECVASNNVGEISVSTRLTVL-REDQIPRGFPTIDMGPQLKVVERTRT 142
Query: 215 ST 216
+T
Sbjct: 143 AT 144
Score = 29.5 bits (63), Expect = 9.6
Identities = 21/76 (27%), Positives = 32/76 (42%), Gaps = 6/76 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G +V C G+P P ++W AE + E G L++ V YTC
Sbjct: 250 GGSVNITCVAVGSPMPYVKWMLGAEDLTP----EDDMPIGRNVLELNDV--RQSANYTCV 303
Query: 66 ASNCLGKAKSNACLVV 81
A + LG ++ A + V
Sbjct: 304 AMSTLGVIEAIAQITV 319
>AL583805-2|CAH70443.2| 1912|Homo sapiens protein tyrosine
phosphatase, receptor type, D protein.
Length = 1912
Score = 70.1 bits (164), Expect = 6e-12
Identities = 60/192 (31%), Positives = 80/192 (41%), Gaps = 15/192 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTAR-LKIKQV-TAEDEGTYT 63
G F CQ TG+P P I W + + + +DDG+ L+I+ + T DE Y
Sbjct: 38 GGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYE 97
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
C ASN +G+ + L V ++ + PT P KVVE T CA GNP
Sbjct: 98 CVASNNVGEISVSTRLTVLREDQIP----RGFPTIDMGPQLKVVERTRTATMLCAASGNP 153
Query: 124 SPWASWDKDGSIITPS---ARITVKEKEE-----IMRILEIDEVSIEDVGIYRITVENEL 175
P +W KD + S RI E I L+I++ D G Y N
Sbjct: 154 DPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQSEESDQGKYECVATNSA 213
Query: 176 G-RAEASARLEV 186
G R A A L V
Sbjct: 214 GTRYSAPANLYV 225
Score = 60.1 bits (139), Expect = 6e-09
Identities = 52/189 (27%), Positives = 78/189 (41%), Gaps = 21/189 (11%)
Query: 8 TVEFECQVTGNPDPDIRWFH-YAEVIRD-----CADFESSYDDGT---ARLKIKQVTAED 58
T C +GNPDP+I WF + V S GT L+I+Q D
Sbjct: 142 TATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQSEESD 201
Query: 59 EGTYTCEASNCLG-KAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKC 117
+G Y C A+N G + + A L V R + R++ P F P N + G +V C
Sbjct: 202 QGKYECVATNSAGTRYSAPANLYVRELREV----RRVPPRFSIPPTNHEIMPGGSVNITC 257
Query: 118 AVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGR 177
G+P P+ W +TP + + +LE+++V Y + LG
Sbjct: 258 VAVGSPMPYVKWMLGAEDLTPEDDMPIGR-----NVLELNDV--RQSANYTCVAMSTLGV 310
Query: 178 AEASARLEV 186
EA A++ V
Sbjct: 311 IEAIAQITV 319
Score = 40.7 bits (91), Expect = 0.004
Identities = 29/122 (23%), Positives = 48/122 (39%), Gaps = 2/122 (1%)
Query: 96 PTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILE 155
P F P ++ G +F C G+P P W+K G ++ ++ + +L
Sbjct: 24 PRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLR 83
Query: 156 IDEV-SIEDVGIYRITVENELGRAEASARLEVITRSGKFYGGLRAYSASPRKCLSYRRRP 214
I + + D IY N +G S RL V+ R + G P+ + R R
Sbjct: 84 IQPLRTPRDEAIYECVASNNVGEISVSTRLTVL-REDQIPRGFPTIDMGPQLKVVERTRT 142
Query: 215 ST 216
+T
Sbjct: 143 AT 144
Score = 29.5 bits (63), Expect = 9.6
Identities = 21/76 (27%), Positives = 32/76 (42%), Gaps = 6/76 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G +V C G+P P ++W AE + E G L++ V YTC
Sbjct: 250 GGSVNITCVAVGSPMPYVKWMLGAEDLTP----EDDMPIGRNVLELNDV--RQSANYTCV 303
Query: 66 ASNCLGKAKSNACLVV 81
A + LG ++ A + V
Sbjct: 304 AMSTLGVIEAIAQITV 319
>AL445926-1|CAH73847.2| 1912|Homo sapiens protein tyrosine
phosphatase, receptor type, D protein.
Length = 1912
Score = 70.1 bits (164), Expect = 6e-12
Identities = 60/192 (31%), Positives = 80/192 (41%), Gaps = 15/192 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTAR-LKIKQV-TAEDEGTYT 63
G F CQ TG+P P I W + + + +DDG+ L+I+ + T DE Y
Sbjct: 38 GGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYE 97
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
C ASN +G+ + L V ++ + PT P KVVE T CA GNP
Sbjct: 98 CVASNNVGEISVSTRLTVLREDQIP----RGFPTIDMGPQLKVVERTRTATMLCAASGNP 153
Query: 124 SPWASWDKDGSIITPS---ARITVKEKEE-----IMRILEIDEVSIEDVGIYRITVENEL 175
P +W KD + S RI E I L+I++ D G Y N
Sbjct: 154 DPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQSEESDQGKYECVATNSA 213
Query: 176 G-RAEASARLEV 186
G R A A L V
Sbjct: 214 GTRYSAPANLYV 225
Score = 60.1 bits (139), Expect = 6e-09
Identities = 52/189 (27%), Positives = 78/189 (41%), Gaps = 21/189 (11%)
Query: 8 TVEFECQVTGNPDPDIRWFH-YAEVIRD-----CADFESSYDDGT---ARLKIKQVTAED 58
T C +GNPDP+I WF + V S GT L+I+Q D
Sbjct: 142 TATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQSEESD 201
Query: 59 EGTYTCEASNCLG-KAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKC 117
+G Y C A+N G + + A L V R + R++ P F P N + G +V C
Sbjct: 202 QGKYECVATNSAGTRYSAPANLYVRELREV----RRVPPRFSIPPTNHEIMPGGSVNITC 257
Query: 118 AVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGR 177
G+P P+ W +TP + + +LE+++V Y + LG
Sbjct: 258 VAVGSPMPYVKWMLGAEDLTPEDDMPIGR-----NVLELNDV--RQSANYTCVAMSTLGV 310
Query: 178 AEASARLEV 186
EA A++ V
Sbjct: 311 IEAIAQITV 319
Score = 40.7 bits (91), Expect = 0.004
Identities = 29/122 (23%), Positives = 48/122 (39%), Gaps = 2/122 (1%)
Query: 96 PTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILE 155
P F P ++ G +F C G+P P W+K G ++ ++ + +L
Sbjct: 24 PRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLR 83
Query: 156 IDEV-SIEDVGIYRITVENELGRAEASARLEVITRSGKFYGGLRAYSASPRKCLSYRRRP 214
I + + D IY N +G S RL V+ R + G P+ + R R
Sbjct: 84 IQPLRTPRDEAIYECVASNNVGEISVSTRLTVL-REDQIPRGFPTIDMGPQLKVVERTRT 142
Query: 215 ST 216
+T
Sbjct: 143 AT 144
Score = 29.5 bits (63), Expect = 9.6
Identities = 21/76 (27%), Positives = 32/76 (42%), Gaps = 6/76 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G +V C G+P P ++W AE + E G L++ V YTC
Sbjct: 250 GGSVNITCVAVGSPMPYVKWMLGAEDLTP----EDDMPIGRNVLELNDV--RQSANYTCV 303
Query: 66 ASNCLGKAKSNACLVV 81
A + LG ++ A + V
Sbjct: 304 AMSTLGVIEAIAQITV 319
>AL391822-6|CAI14661.1| 1157|Homo sapiens neurofascin homolog
(chicken) protein.
Length = 1157
Score = 70.1 bits (164), Expect = 6e-12
Identities = 55/180 (30%), Positives = 83/180 (46%), Gaps = 20/180 (11%)
Query: 12 ECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLG 71
+C G+P P +RWF + Y++G+ L+IK + ED+G YTC A+N LG
Sbjct: 445 DCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGS--LEIKMIRKEDQGIYTCVATNILG 502
Query: 72 KAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS--PWASW 129
KA++ L V R+ Y P ++V G V +C VK +PS SW
Sbjct: 503 KAENQVRLEVKDPTRI-----------YRMPEDQVARRGTTVQLECRVKHDPSLKLTVSW 551
Query: 130 DKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVITR 189
KD + R +K++++ + I + E D G Y EL + A A L V+ R
Sbjct: 552 LKDDEPLYIGNR--MKKEDDSLTIFGVAE---RDQGSYTCVASTELDQDLAKAYLTVLGR 606
Score = 59.7 bits (138), Expect = 8e-09
Identities = 44/176 (25%), Positives = 72/176 (40%), Gaps = 16/176 (9%)
Query: 12 ECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLG 71
EC +G P PDI W+ D ++ +++ L+I V+ ED G Y C ASN +G
Sbjct: 261 ECIASGVPTPDIAWYKKGG---DLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMG 317
Query: 72 KAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDK 131
+ + V + AP + P N ++ GE+ C GNP P W
Sbjct: 318 SIRHTISVRV-----------KAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMV 366
Query: 132 DGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVI 187
+G + + +E + + I +Y+ NE G A+A + V+
Sbjct: 367 NGEPLQSAP--PNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVL 420
Score = 50.4 bits (115), Expect = 5e-06
Identities = 48/188 (25%), Positives = 69/188 (36%), Gaps = 17/188 (9%)
Query: 1 MLSCDGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEG 60
++ G+ C+ GNP P ++W E ++ + G + +
Sbjct: 340 LILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDT-IIFRDTQISSRA 398
Query: 61 TYTCEASNCLGKAKSNACLVVYHT-RRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAV 119
Y C SN G +NA + V R+ SP Q+ +N+ C
Sbjct: 399 VYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVIL---YNR-------TRLDCPF 448
Query: 120 KGNPSPWASWDKDG-SIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRA 178
G+P P W K+G V E LEI + ED GIY N LG+A
Sbjct: 449 FGSPIPTLRWFKNGQGSNLDGGNYHVYENGS----LEIKMIRKEDQGIYTCVATNILGKA 504
Query: 179 EASARLEV 186
E RLEV
Sbjct: 505 ENQVRLEV 512
Score = 38.7 bits (86), Expect = 0.016
Identities = 37/128 (28%), Positives = 47/128 (36%), Gaps = 14/128 (10%)
Query: 7 DTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSY--DDGTARLKIKQ--VTAEDEGTY 62
D + EC+ GNP P W + D S GT + + E EG Y
Sbjct: 51 DNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEY 110
Query: 63 TCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKC-AVKG 121
C A N G A SN + L P + P VV+EG +T +C G
Sbjct: 111 QCFARNKFGTALSNRIRLQVSKSPL-WPKENLDPV--------VVQEGAPLTLQCNPPPG 161
Query: 122 NPSPWASW 129
PSP W
Sbjct: 162 LPSPVIFW 169
Score = 34.7 bits (76), Expect = 0.26
Identities = 22/73 (30%), Positives = 36/73 (49%), Gaps = 4/73 (5%)
Query: 104 NKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIED 163
+++V G ++ +C G P+P +W K G + PS + + E + L I VS ED
Sbjct: 249 SQMVLRGMDLLLECIASGVPTPDIAWYKKGGDL-PSDK---AKFENFNKALRITNVSEED 304
Query: 164 VGIYRITVENELG 176
G Y N++G
Sbjct: 305 SGEYFCLASNKMG 317
Score = 31.9 bits (69), Expect = 1.8
Identities = 21/85 (24%), Positives = 40/85 (47%), Gaps = 4/85 (4%)
Query: 106 VVEEGENVTFKCAVKGNPSPWASWDKDGSI--ITPSARITVKEKEEIMRI-LEIDEVSIE 162
+V+ +N+ +C KGNP+P W ++ I R++++ + + I E
Sbjct: 46 IVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEE 105
Query: 163 DVGIYRITVENELGRAEAS-ARLEV 186
G Y+ N+ G A ++ RL+V
Sbjct: 106 YEGEYQCFARNKFGTALSNRIRLQV 130
>AL391822-3|CAI14658.1| 1174|Homo sapiens neurofascin homolog
(chicken) protein.
Length = 1174
Score = 70.1 bits (164), Expect = 6e-12
Identities = 55/180 (30%), Positives = 83/180 (46%), Gaps = 20/180 (11%)
Query: 12 ECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLG 71
+C G+P P +RWF + Y++G+ L+IK + ED+G YTC A+N LG
Sbjct: 462 DCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGS--LEIKMIRKEDQGIYTCVATNILG 519
Query: 72 KAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS--PWASW 129
KA++ L V R+ Y P ++V G V +C VK +PS SW
Sbjct: 520 KAENQVRLEVKDPTRI-----------YRMPEDQVARRGTTVQLECRVKHDPSLKLTVSW 568
Query: 130 DKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVITR 189
KD + R +K++++ + I + E D G Y EL + A A L V+ R
Sbjct: 569 LKDDEPLYIGNR--MKKEDDSLTIFGVAE---RDQGSYTCVASTELDQDLAKAYLTVLGR 623
Score = 59.7 bits (138), Expect = 8e-09
Identities = 44/176 (25%), Positives = 72/176 (40%), Gaps = 16/176 (9%)
Query: 12 ECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLG 71
EC +G P PDI W+ D ++ +++ L+I V+ ED G Y C ASN +G
Sbjct: 278 ECIASGVPTPDIAWYKKGG---DLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMG 334
Query: 72 KAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDK 131
+ + V + AP + P N ++ GE+ C GNP P W
Sbjct: 335 SIRHTISVRV-----------KAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMV 383
Query: 132 DGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVI 187
+G + + +E + + I +Y+ NE G A+A + V+
Sbjct: 384 NGEPLQSAP--PNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVL 437
Score = 50.4 bits (115), Expect = 5e-06
Identities = 48/188 (25%), Positives = 69/188 (36%), Gaps = 17/188 (9%)
Query: 1 MLSCDGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEG 60
++ G+ C+ GNP P ++W E ++ + G + +
Sbjct: 357 LILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDT-IIFRDTQISSRA 415
Query: 61 TYTCEASNCLGKAKSNACLVVYHT-RRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAV 119
Y C SN G +NA + V R+ SP Q+ +N+ C
Sbjct: 416 VYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVIL---YNR-------TRLDCPF 465
Query: 120 KGNPSPWASWDKDG-SIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRA 178
G+P P W K+G V E LEI + ED GIY N LG+A
Sbjct: 466 FGSPIPTLRWFKNGQGSNLDGGNYHVYENGS----LEIKMIRKEDQGIYTCVATNILGKA 521
Query: 179 EASARLEV 186
E RLEV
Sbjct: 522 ENQVRLEV 529
Score = 38.7 bits (86), Expect = 0.016
Identities = 37/128 (28%), Positives = 47/128 (36%), Gaps = 14/128 (10%)
Query: 7 DTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSY--DDGTARLKIKQ--VTAEDEGTY 62
D + EC+ GNP P W + D S GT + + E EG Y
Sbjct: 51 DNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEY 110
Query: 63 TCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKC-AVKG 121
C A N G A SN + L P + P VV+EG +T +C G
Sbjct: 111 QCFARNKFGTALSNRIRLQVSKSPL-WPKENLDPV--------VVQEGAPLTLQCNPPPG 161
Query: 122 NPSPWASW 129
PSP W
Sbjct: 162 LPSPVIFW 169
Score = 34.7 bits (76), Expect = 0.26
Identities = 22/73 (30%), Positives = 36/73 (49%), Gaps = 4/73 (5%)
Query: 104 NKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIED 163
+++V G ++ +C G P+P +W K G + PS + + E + L I VS ED
Sbjct: 266 SQMVLRGMDLLLECIASGVPTPDIAWYKKGGDL-PSDK---AKFENFNKALRITNVSEED 321
Query: 164 VGIYRITVENELG 176
G Y N++G
Sbjct: 322 SGEYFCLASNKMG 334
Score = 31.9 bits (69), Expect = 1.8
Identities = 21/85 (24%), Positives = 40/85 (47%), Gaps = 4/85 (4%)
Query: 106 VVEEGENVTFKCAVKGNPSPWASWDKDGSI--ITPSARITVKEKEEIMRI-LEIDEVSIE 162
+V+ +N+ +C KGNP+P W ++ I R++++ + + I E
Sbjct: 46 IVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEE 105
Query: 163 DVGIYRITVENELGRAEAS-ARLEV 186
G Y+ N+ G A ++ RL+V
Sbjct: 106 YEGEYQCFARNKFGTALSNRIRLQV 130
>AL356584-1|CAI16146.2| 1912|Homo sapiens protein tyrosine
phosphatase, receptor type, D protein.
Length = 1912
Score = 70.1 bits (164), Expect = 6e-12
Identities = 60/192 (31%), Positives = 80/192 (41%), Gaps = 15/192 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTAR-LKIKQV-TAEDEGTYT 63
G F CQ TG+P P I W + + + +DDG+ L+I+ + T DE Y
Sbjct: 38 GGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYE 97
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
C ASN +G+ + L V ++ + PT P KVVE T CA GNP
Sbjct: 98 CVASNNVGEISVSTRLTVLREDQIP----RGFPTIDMGPQLKVVERTRTATMLCAASGNP 153
Query: 124 SPWASWDKDGSIITPS---ARITVKEKEE-----IMRILEIDEVSIEDVGIYRITVENEL 175
P +W KD + S RI E I L+I++ D G Y N
Sbjct: 154 DPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQSEESDQGKYECVATNSA 213
Query: 176 G-RAEASARLEV 186
G R A A L V
Sbjct: 214 GTRYSAPANLYV 225
Score = 60.1 bits (139), Expect = 6e-09
Identities = 52/189 (27%), Positives = 78/189 (41%), Gaps = 21/189 (11%)
Query: 8 TVEFECQVTGNPDPDIRWFH-YAEVIRD-----CADFESSYDDGT---ARLKIKQVTAED 58
T C +GNPDP+I WF + V S GT L+I+Q D
Sbjct: 142 TATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQSEESD 201
Query: 59 EGTYTCEASNCLG-KAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKC 117
+G Y C A+N G + + A L V R + R++ P F P N + G +V C
Sbjct: 202 QGKYECVATNSAGTRYSAPANLYVRELREV----RRVPPRFSIPPTNHEIMPGGSVNITC 257
Query: 118 AVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGR 177
G+P P+ W +TP + + +LE+++V Y + LG
Sbjct: 258 VAVGSPMPYVKWMLGAEDLTPEDDMPIGR-----NVLELNDV--RQSANYTCVAMSTLGV 310
Query: 178 AEASARLEV 186
EA A++ V
Sbjct: 311 IEAIAQITV 319
Score = 40.7 bits (91), Expect = 0.004
Identities = 29/122 (23%), Positives = 48/122 (39%), Gaps = 2/122 (1%)
Query: 96 PTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILE 155
P F P ++ G +F C G+P P W+K G ++ ++ + +L
Sbjct: 24 PRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLR 83
Query: 156 IDEV-SIEDVGIYRITVENELGRAEASARLEVITRSGKFYGGLRAYSASPRKCLSYRRRP 214
I + + D IY N +G S RL V+ R + G P+ + R R
Sbjct: 84 IQPLRTPRDEAIYECVASNNVGEISVSTRLTVL-REDQIPRGFPTIDMGPQLKVVERTRT 142
Query: 215 ST 216
+T
Sbjct: 143 AT 144
Score = 29.5 bits (63), Expect = 9.6
Identities = 21/76 (27%), Positives = 32/76 (42%), Gaps = 6/76 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G +V C G+P P ++W AE + E G L++ V YTC
Sbjct: 250 GGSVNITCVAVGSPMPYVKWMLGAEDLTP----EDDMPIGRNVLELNDV--RQSANYTCV 303
Query: 66 ASNCLGKAKSNACLVV 81
A + LG ++ A + V
Sbjct: 304 AMSTLGVIEAIAQITV 319
>AL137125-1|CAH70912.2| 1912|Homo sapiens protein tyrosine
phosphatase, receptor type, D protein.
Length = 1912
Score = 70.1 bits (164), Expect = 6e-12
Identities = 60/192 (31%), Positives = 80/192 (41%), Gaps = 15/192 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTAR-LKIKQV-TAEDEGTYT 63
G F CQ TG+P P I W + + + +DDG+ L+I+ + T DE Y
Sbjct: 38 GGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYE 97
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
C ASN +G+ + L V ++ + PT P KVVE T CA GNP
Sbjct: 98 CVASNNVGEISVSTRLTVLREDQIP----RGFPTIDMGPQLKVVERTRTATMLCAASGNP 153
Query: 124 SPWASWDKDGSIITPS---ARITVKEKEE-----IMRILEIDEVSIEDVGIYRITVENEL 175
P +W KD + S RI E I L+I++ D G Y N
Sbjct: 154 DPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQSEESDQGKYECVATNSA 213
Query: 176 G-RAEASARLEV 186
G R A A L V
Sbjct: 214 GTRYSAPANLYV 225
Score = 60.1 bits (139), Expect = 6e-09
Identities = 52/189 (27%), Positives = 78/189 (41%), Gaps = 21/189 (11%)
Query: 8 TVEFECQVTGNPDPDIRWFH-YAEVIRD-----CADFESSYDDGT---ARLKIKQVTAED 58
T C +GNPDP+I WF + V S GT L+I+Q D
Sbjct: 142 TATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQSEESD 201
Query: 59 EGTYTCEASNCLG-KAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKC 117
+G Y C A+N G + + A L V R + R++ P F P N + G +V C
Sbjct: 202 QGKYECVATNSAGTRYSAPANLYVRELREV----RRVPPRFSIPPTNHEIMPGGSVNITC 257
Query: 118 AVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGR 177
G+P P+ W +TP + + +LE+++V Y + LG
Sbjct: 258 VAVGSPMPYVKWMLGAEDLTPEDDMPIGR-----NVLELNDV--RQSANYTCVAMSTLGV 310
Query: 178 AEASARLEV 186
EA A++ V
Sbjct: 311 IEAIAQITV 319
Score = 40.7 bits (91), Expect = 0.004
Identities = 29/122 (23%), Positives = 48/122 (39%), Gaps = 2/122 (1%)
Query: 96 PTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILE 155
P F P ++ G +F C G+P P W+K G ++ ++ + +L
Sbjct: 24 PRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLR 83
Query: 156 IDEV-SIEDVGIYRITVENELGRAEASARLEVITRSGKFYGGLRAYSASPRKCLSYRRRP 214
I + + D IY N +G S RL V+ R + G P+ + R R
Sbjct: 84 IQPLRTPRDEAIYECVASNNVGEISVSTRLTVL-REDQIPRGFPTIDMGPQLKVVERTRT 142
Query: 215 ST 216
+T
Sbjct: 143 AT 144
Score = 29.5 bits (63), Expect = 9.6
Identities = 21/76 (27%), Positives = 32/76 (42%), Gaps = 6/76 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G +V C G+P P ++W AE + E G L++ V YTC
Sbjct: 250 GGSVNITCVAVGSPMPYVKWMLGAEDLTP----EDDMPIGRNVLELNDV--RQSANYTCV 303
Query: 66 ASNCLGKAKSNACLVV 81
A + LG ++ A + V
Sbjct: 304 AMSTLGVIEAIAQITV 319
>AF144477-1|AAD44754.1| 498|Homo sapiens myotilin protein.
Length = 498
Score = 70.1 bits (164), Expect = 6e-12
Identities = 50/187 (26%), Positives = 83/187 (44%), Gaps = 8/187 (4%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIR-DCADFESSYDDGTARLKIKQVTAEDEGTYT 63
+G + +V+G P PD+ W+ ++ D + G L + V A D G Y
Sbjct: 263 EGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYA 322
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
C A N G+A L V + + AP F P +K V EG++V +C + P
Sbjct: 323 CVAKNRAGEATFTVQLDVL------AKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIP 376
Query: 124 SPWASWDKDGSIIT-PSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASA 182
P W ++ ++ + RI++ + L I +V+ +D G Y ++ NE G +
Sbjct: 377 PPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNT 436
Query: 183 RLEVITR 189
RL+V R
Sbjct: 437 RLDVTAR 443
Score = 54.0 bits (124), Expect = 4e-07
Identities = 36/102 (35%), Positives = 51/102 (50%), Gaps = 5/102 (4%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTAR--LKIKQVTAEDEGTY 62
+GD+V+ ECQ++ P P + W E+++ D S Y D T R L IK V +D G Y
Sbjct: 362 EGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWY 421
Query: 63 TCEASNCLGKAKSNACLVV--YHTRRLSSPGR-QMAPTFYTY 101
T A N G N L V + L +P + ++ PTF Y
Sbjct: 422 TVSAVNEAGVTTCNTRLDVTARPNQTLPAPKQLRVRPTFSKY 463
Score = 43.6 bits (98), Expect = 6e-04
Identities = 25/97 (25%), Positives = 40/97 (41%)
Query: 96 PTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILE 155
P F P N ++EG V G P+P SW +G + + E+ + L
Sbjct: 250 PRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLI 309
Query: 156 IDEVSIEDVGIYRITVENELGRAEASARLEVITRSGK 192
+ V D G Y +N G A + +L+V+ + K
Sbjct: 310 FEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHK 346
>AF133820-1|AAD29051.2| 498|Homo sapiens titin-like protein
protein.
Length = 498
Score = 70.1 bits (164), Expect = 6e-12
Identities = 50/187 (26%), Positives = 83/187 (44%), Gaps = 8/187 (4%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIR-DCADFESSYDDGTARLKIKQVTAEDEGTYT 63
+G + +V+G P PD+ W+ ++ D + G L + V A D G Y
Sbjct: 263 EGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLIFEVVRASDAGAYA 322
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
C A N G+A L V + + AP F P +K V EG++V +C + P
Sbjct: 323 CVAKNRAGEATFTVQLDVL------AKEHKRAPMFIYKPQSKKVLEGDSVKLECQISAIP 376
Query: 124 SPWASWDKDGSIIT-PSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASA 182
P W ++ ++ + RI++ + L I +V+ +D G Y ++ NE G +
Sbjct: 377 PPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWYTVSAVNEAGVTTCNT 436
Query: 183 RLEVITR 189
RL+V R
Sbjct: 437 RLDVTAR 443
Score = 54.0 bits (124), Expect = 4e-07
Identities = 36/102 (35%), Positives = 51/102 (50%), Gaps = 5/102 (4%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTAR--LKIKQVTAEDEGTY 62
+GD+V+ ECQ++ P P + W E+++ D S Y D T R L IK V +D G Y
Sbjct: 362 EGDSVKLECQISAIPPPKLFWKRNNEMVQFNTDRISLYQDNTGRVTLLIKDVNKKDAGWY 421
Query: 63 TCEASNCLGKAKSNACLVV--YHTRRLSSPGR-QMAPTFYTY 101
T A N G N L V + L +P + ++ PTF Y
Sbjct: 422 TVSAVNEAGVTTCNTRLDVTARPNQTLPAPKQLRVRPTFSKY 463
Score = 43.6 bits (98), Expect = 6e-04
Identities = 25/97 (25%), Positives = 40/97 (41%)
Query: 96 PTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILE 155
P F P N ++EG V G P+P SW +G + + E+ + L
Sbjct: 250 PRFIQVPENMSIDEGRFCRMDFKVSGLPAPDVSWYLNGRTVQSDDLHKMIVSEKGLHSLI 309
Query: 156 IDEVSIEDVGIYRITVENELGRAEASARLEVITRSGK 192
+ V D G Y +N G A + +L+V+ + K
Sbjct: 310 FEVVRASDAGAYACVAKNRAGEATFTVQLDVLAKEHK 346
>AB211400-1|BAE79816.1| 1912|Homo sapiens protein tyrosine
phosphatase receptor type D protein.
Length = 1912
Score = 70.1 bits (164), Expect = 6e-12
Identities = 60/192 (31%), Positives = 80/192 (41%), Gaps = 15/192 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTAR-LKIKQV-TAEDEGTYT 63
G F CQ TG+P P I W + + + +DDG+ L+I+ + T DE Y
Sbjct: 38 GGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYE 97
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
C ASN +G+ + L V ++ + PT P KVVE T CA GNP
Sbjct: 98 CVASNNVGEISVSTRLTVLREDQIP----RGFPTIDMGPQLKVVERTRTATMLCAASGNP 153
Query: 124 SPWASWDKDGSIITPS---ARITVKEKEE-----IMRILEIDEVSIEDVGIYRITVENEL 175
P +W KD + S RI E I L+I++ D G Y N
Sbjct: 154 DPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQSEESDQGKYECVATNSA 213
Query: 176 G-RAEASARLEV 186
G R A A L V
Sbjct: 214 GTRYSAPANLYV 225
Score = 60.1 bits (139), Expect = 6e-09
Identities = 52/189 (27%), Positives = 78/189 (41%), Gaps = 21/189 (11%)
Query: 8 TVEFECQVTGNPDPDIRWFH-YAEVIRD-----CADFESSYDDGT---ARLKIKQVTAED 58
T C +GNPDP+I WF + V S GT L+I+Q D
Sbjct: 142 TATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSESIGGTPIRGALQIEQSEESD 201
Query: 59 EGTYTCEASNCLG-KAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKC 117
+G Y C A+N G + + A L V R + R++ P F P N + G +V C
Sbjct: 202 QGKYECVATNSAGTRYSAPANLYVRELREV----RRVPPRFSIPPTNHEIMPGGSVNITC 257
Query: 118 AVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGR 177
G+P P+ W +TP + + +LE+++V Y + LG
Sbjct: 258 VAVGSPMPYVKWMLGAEDLTPEDDMPIGR-----NVLELNDV--RQSANYTCVAMSTLGV 310
Query: 178 AEASARLEV 186
EA A++ V
Sbjct: 311 IEAIAQITV 319
Score = 40.7 bits (91), Expect = 0.004
Identities = 29/122 (23%), Positives = 48/122 (39%), Gaps = 2/122 (1%)
Query: 96 PTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILE 155
P F P ++ G +F C G+P P W+K G ++ ++ + +L
Sbjct: 24 PRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLR 83
Query: 156 IDEV-SIEDVGIYRITVENELGRAEASARLEVITRSGKFYGGLRAYSASPRKCLSYRRRP 214
I + + D IY N +G S RL V+ R + G P+ + R R
Sbjct: 84 IQPLRTPRDEAIYECVASNNVGEISVSTRLTVL-REDQIPRGFPTIDMGPQLKVVERTRT 142
Query: 215 ST 216
+T
Sbjct: 143 AT 144
Score = 29.5 bits (63), Expect = 9.6
Identities = 21/76 (27%), Positives = 32/76 (42%), Gaps = 6/76 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G +V C G+P P ++W AE + E G L++ V YTC
Sbjct: 250 GGSVNITCVAVGSPMPYVKWMLGAEDLTP----EDDMPIGRNVLELNDV--RQSANYTCV 303
Query: 66 ASNCLGKAKSNACLVV 81
A + LG ++ A + V
Sbjct: 304 AMSTLGVIEAIAQITV 319
>AB177861-1|BAD66839.1| 836|Homo sapiens KIAA0756 splice variant 1
protein.
Length = 836
Score = 70.1 bits (164), Expect = 6e-12
Identities = 55/180 (30%), Positives = 83/180 (46%), Gaps = 20/180 (11%)
Query: 12 ECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLG 71
+C G+P P +RWF + Y++G+ L+IK + ED+G YTC A+N LG
Sbjct: 259 DCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGS--LEIKMIRKEDQGIYTCVATNILG 316
Query: 72 KAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS--PWASW 129
KA++ L V R+ Y P ++V G V +C VK +PS SW
Sbjct: 317 KAENQVRLEVKDPTRI-----------YRMPEDQVARRGTTVQLECRVKHDPSLKLTVSW 365
Query: 130 DKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVITR 189
KD + R +K++++ + I + E D G Y EL + A A L V+ R
Sbjct: 366 LKDDEPLYIGNR--MKKEDDSLTIFGVAE---RDQGSYTCVASTELDQDLAKAYLTVLGR 420
Score = 59.7 bits (138), Expect = 8e-09
Identities = 44/176 (25%), Positives = 72/176 (40%), Gaps = 16/176 (9%)
Query: 12 ECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLG 71
EC +G P PDI W+ D ++ +++ L+I V+ ED G Y C ASN +G
Sbjct: 75 ECIASGVPTPDIAWYKKGG---DLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMG 131
Query: 72 KAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDK 131
+ + V + AP + P N ++ GE+ C GNP P W
Sbjct: 132 SIRHTISVRV-----------KAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMV 180
Query: 132 DGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVI 187
+G + + +E + + I +Y+ NE G A+A + V+
Sbjct: 181 NGEPLQSAP--PNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVL 234
Score = 50.4 bits (115), Expect = 5e-06
Identities = 48/188 (25%), Positives = 69/188 (36%), Gaps = 17/188 (9%)
Query: 1 MLSCDGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEG 60
++ G+ C+ GNP P ++W E ++ + G + +
Sbjct: 154 LILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDT-IIFRDTQISSRA 212
Query: 61 TYTCEASNCLGKAKSNACLVVYHT-RRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAV 119
Y C SN G +NA + V R+ SP Q+ +N+ C
Sbjct: 213 VYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVIL---YNR-------TRLDCPF 262
Query: 120 KGNPSPWASWDKDG-SIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRA 178
G+P P W K+G V E LEI + ED GIY N LG+A
Sbjct: 263 FGSPIPTLRWFKNGQGSNLDGGNYHVYENGS----LEIKMIRKEDQGIYTCVATNILGKA 318
Query: 179 EASARLEV 186
E RLEV
Sbjct: 319 ENQVRLEV 326
Score = 34.7 bits (76), Expect = 0.26
Identities = 22/73 (30%), Positives = 36/73 (49%), Gaps = 4/73 (5%)
Query: 104 NKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIED 163
+++V G ++ +C G P+P +W K G + PS + + E + L I VS ED
Sbjct: 63 SQMVLRGMDLLLECIASGVPTPDIAWYKKGGDL-PSDK---AKFENFNKALRITNVSEED 118
Query: 164 VGIYRITVENELG 176
G Y N++G
Sbjct: 119 SGEYFCLASNKMG 131
>AB018299-1|BAA34476.3| 1222|Homo sapiens KIAA0756 protein protein.
Length = 1222
Score = 70.1 bits (164), Expect = 6e-12
Identities = 55/180 (30%), Positives = 83/180 (46%), Gaps = 20/180 (11%)
Query: 12 ECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLG 71
+C G+P P +RWF + Y++G+ L+IK + ED+G YTC A+N LG
Sbjct: 515 DCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGS--LEIKMIRKEDQGIYTCVATNILG 572
Query: 72 KAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS--PWASW 129
KA++ L V R+ Y P ++V G V +C VK +PS SW
Sbjct: 573 KAENQVRLEVKDPTRI-----------YRMPEDQVARRGTTVQLECRVKHDPSLKLTVSW 621
Query: 130 DKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVITR 189
KD + R +K++++ + I + E D G Y EL + A A L V+ R
Sbjct: 622 LKDDEPLYIGNR--MKKEDDSLTIFGVAE---RDQGSYTCVASTELDQDLAKAYLTVLGR 676
Score = 59.7 bits (138), Expect = 8e-09
Identities = 44/176 (25%), Positives = 72/176 (40%), Gaps = 16/176 (9%)
Query: 12 ECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLG 71
EC +G P PDI W+ D ++ +++ L+I V+ ED G Y C ASN +G
Sbjct: 331 ECIASGVPTPDIAWYKKGG---DLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMG 387
Query: 72 KAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDK 131
+ + V + AP + P N ++ GE+ C GNP P W
Sbjct: 388 SIRHTISVRV-----------KAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMV 436
Query: 132 DGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVI 187
+G + + +E + + I +Y+ NE G A+A + V+
Sbjct: 437 NGEPLQSAP--PNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVL 490
Score = 50.4 bits (115), Expect = 5e-06
Identities = 48/188 (25%), Positives = 69/188 (36%), Gaps = 17/188 (9%)
Query: 1 MLSCDGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEG 60
++ G+ C+ GNP P ++W E ++ + G + +
Sbjct: 410 LILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDT-IIFRDTQISSRA 468
Query: 61 TYTCEASNCLGKAKSNACLVVYHT-RRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAV 119
Y C SN G +NA + V R+ SP Q+ +N+ C
Sbjct: 469 VYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVIL---YNR-------TRLDCPF 518
Query: 120 KGNPSPWASWDKDG-SIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRA 178
G+P P W K+G V E LEI + ED GIY N LG+A
Sbjct: 519 FGSPIPTLRWFKNGQGSNLDGGNYHVYENGS----LEIKMIRKEDQGIYTCVATNILGKA 574
Query: 179 EASARLEV 186
E RLEV
Sbjct: 575 ENQVRLEV 582
Score = 38.7 bits (86), Expect = 0.016
Identities = 37/128 (28%), Positives = 47/128 (36%), Gaps = 14/128 (10%)
Query: 7 DTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSY--DDGTARLKIKQ--VTAEDEGTY 62
D + EC+ GNP P W + D S GT + + E EG Y
Sbjct: 104 DNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEY 163
Query: 63 TCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKC-AVKG 121
C A N G A SN + L P + P VV+EG +T +C G
Sbjct: 164 QCFARNKFGTALSNRIRLQVSKSPL-WPKENLDPV--------VVQEGAPLTLQCNPPPG 214
Query: 122 NPSPWASW 129
PSP W
Sbjct: 215 LPSPVIFW 222
Score = 34.7 bits (76), Expect = 0.26
Identities = 22/73 (30%), Positives = 36/73 (49%), Gaps = 4/73 (5%)
Query: 104 NKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIED 163
+++V G ++ +C G P+P +W K G + PS + + E + L I VS ED
Sbjct: 319 SQMVLRGMDLLLECIASGVPTPDIAWYKKGGDL-PSDK---AKFENFNKALRITNVSEED 374
Query: 164 VGIYRITVENELG 176
G Y N++G
Sbjct: 375 SGEYFCLASNKMG 387
Score = 31.9 bits (69), Expect = 1.8
Identities = 21/85 (24%), Positives = 40/85 (47%), Gaps = 4/85 (4%)
Query: 106 VVEEGENVTFKCAVKGNPSPWASWDKDGSI--ITPSARITVKEKEEIMRI-LEIDEVSIE 162
+V+ +N+ +C KGNP+P W ++ I R++++ + + I E
Sbjct: 99 IVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEE 158
Query: 163 DVGIYRITVENELGRAEAS-ARLEV 186
G Y+ N+ G A ++ RL+V
Sbjct: 159 YEGEYQCFARNKFGTALSNRIRLQV 183
>AY603755-1|AAT80901.1| 3094|Homo sapiens striated muscle
preferentially expressed protein protein.
Length = 3094
Score = 69.7 bits (163), Expect = 7e-12
Identities = 48/182 (26%), Positives = 79/182 (43%), Gaps = 11/182 (6%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCA-DFESSYDDGTARLKIKQVTAEDEGTYTC 64
G+ FEC V G D ++ W +++ + +D +L + V +D G YTC
Sbjct: 853 GEMALFECLVAGPTDVEVDWLCRGRLLQPALLKCKMHFDGRKCKLLLTSVHEDDSGVYTC 912
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
+ S + +A L V + +AP F + V EG F C + G P
Sbjct: 913 KLSTAKDELTCSARLTVRPS---------LAPLFTRLLEDVEVLEGRAARFDCKISGTPP 963
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
P +W G + S + +++ + + L I V ED G+Y ++ N G+A SA+L
Sbjct: 964 PVVTWTHFGCPMEESENLRLRQ-DGGLHSLHIAHVGSEDEGLYAVSAVNTHGQAHCSAQL 1022
Query: 185 EV 186
V
Sbjct: 1023 YV 1024
Score = 68.9 bits (161), Expect = 1e-11
Identities = 52/202 (25%), Positives = 85/202 (42%), Gaps = 21/202 (10%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G F+C+++G P P + W H+ + + + D G L I V +EDEG Y
Sbjct: 948 EGRAARFDCKISGTPPPVVTWTHFGCPMEESENLRLRQDGGLHSLHIAHVGSEDEGLYAV 1007
Query: 65 EASNCLGKAKSNACLVVYHTRRLSS-PGRQM--APTFYTYPFNKVVEE------------ 109
A N G+A +A L V R +S P ++ P+ P +E
Sbjct: 1008 SAVNTHGQAHCSAQLYVEEPRTAASGPSSKLEKMPSIPEEPEQGELERLSIPDFLRPLQD 1067
Query: 110 -----GENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDV 164
+ +C V G P P SW +G I S + + ++ R++ V +
Sbjct: 1068 LEVGLAKEAMLECQVTGLPYPTISWFHNGHRIQSSDDRRMTQYRDVHRLV-FPAVGPQHA 1126
Query: 165 GIYRITVENELGRAEASARLEV 186
G+Y+ + N+LG+A A L V
Sbjct: 1127 GVYKSVIANKLGKAACYAHLYV 1148
Score = 63.7 bits (148), Expect = 5e-10
Identities = 35/92 (38%), Positives = 46/92 (50%), Gaps = 1/92 (1%)
Query: 95 APTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRIL 154
AP F N VV G +V KC + NP P SW KDGS + R+ ++ + E +L
Sbjct: 592 APVFEIPLQNVVVAPGADVLLKCIITANPPPQVSWHKDGSALRSEGRLLLRAEGERHTLL 651
Query: 155 EIDEVSIEDVGIYRITVENELGRAEASARLEV 186
+ E D G Y T NELG+A +A L V
Sbjct: 652 -LREARAADAGSYMATATNELGQATCAASLTV 682
Score = 58.0 bits (134), Expect = 2e-08
Identities = 34/102 (33%), Positives = 46/102 (45%)
Query: 85 RRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITV 144
RR S G + PTF ++ V EG++V V+G P P SW ++ + P R
Sbjct: 729 RRSSDTGSKAPPTFKVSLMDQSVREGQDVIMSIRVQGEPKPVVSWLRNRQPVRPDQRRFA 788
Query: 145 KEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
+E E + L I D G Y NE G + ARLEV
Sbjct: 789 EEAEGGLCRLRILAAERGDAGFYTCKAVNEYGARQCEARLEV 830
Score = 55.2 bits (127), Expect = 2e-07
Identities = 50/184 (27%), Positives = 69/184 (37%), Gaps = 9/184 (4%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIR-DCADFESSYDDGTARLKIKQVTAEDEGTYT 63
+G V +V G P P + W + +R D F + G RL+I D G YT
Sbjct: 753 EGQDVIMSIRVQGEPKPVVSWLRNRQPVRPDQRRFAEEAEGGLCRLRILAAERGDAGFYT 812
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKV-VEEGENVTFKCAVKGN 122
C+A N G + A L V R R +A P V V GE F+C V G
Sbjct: 813 CKAVNEYGARQCEARLEV----RAHPESRSLA---VLAPLQDVDVGAGEMALFECLVAGP 865
Query: 123 PSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASA 182
W G ++ P+ + L + V +D G+Y + SA
Sbjct: 866 TDVEVDWLCRGRLLQPALLKCKMHFDGRKCKLLLTSVHEDDSGVYTCKLSTAKDELTCSA 925
Query: 183 RLEV 186
RL V
Sbjct: 926 RLTV 929
Score = 53.2 bits (122), Expect = 7e-07
Identities = 46/148 (31%), Positives = 64/148 (43%), Gaps = 14/148 (9%)
Query: 40 SSYDDGTARLKIKQVTAEDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFY 99
S DD L+I +V+ D G TC A N G + C V T L+ AP F
Sbjct: 1311 SQPDDDQYCLRICRVSRRDMGALTCTARNRHG---TQTCSV---TLELAE-----APRFE 1359
Query: 100 TYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARIT-VKEKEEIMRILEIDE 158
+ + V GE F V+G P P W KD ++T S+ ++ V E+ E L +
Sbjct: 1360 SIMEDVEVGAGETARFAVVVEGKPLPDIMWYKDEVLLTESSHVSFVYEENECS--LVVLS 1417
Query: 159 VSIEDVGIYRITVENELGRAEASARLEV 186
+D G+Y T +N G A L V
Sbjct: 1418 TGAQDGGVYTCTAQNLAGEVSCKAELAV 1445
Score = 51.6 bits (118), Expect = 2e-06
Identities = 24/77 (31%), Positives = 36/77 (46%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+T F V G P PDI W+ ++ + + Y++ L + A+D G YTC
Sbjct: 1370 GETARFAVVVEGKPLPDIMWYKDEVLLTESSHVSFVYEENECSLVVLSTGAQDGGVYTCT 1429
Query: 66 ASNCLGKAKSNACLVVY 82
A N G+ A L V+
Sbjct: 1430 AQNLAGEVSCKAELAVH 1446
Score = 44.8 bits (101), Expect = 2e-04
Identities = 37/145 (25%), Positives = 59/145 (40%), Gaps = 5/145 (3%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G V +C +T NP P + W +R + L +++ A D G+Y
Sbjct: 607 GADVLLKCIITANPPPQVSWHKDGSALRSEGRLLLRAEGERHTLLLREARAADAGSYMAT 666
Query: 66 ASNCLGKAKSNACLVVY---HTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGN 122
A+N LG+A A L V T SSP + Y P + E GE +K +
Sbjct: 667 ATNELGQATCAASLTVRPGGSTSPFSSP--ITSDEEYLSPPEEFPEPGETWPRTPTMKPS 724
Query: 123 PSPWASWDKDGSIITPSARITVKEK 147
PS GS P+ ++++ ++
Sbjct: 725 PSQNRRSSDTGSKAPPTFKVSLMDQ 749
Score = 44.4 bits (100), Expect = 3e-04
Identities = 25/97 (25%), Positives = 41/97 (42%)
Query: 96 PTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILE 155
P F+ ++V+ EGE T C P+P SW KD + + + ++ ++L
Sbjct: 2455 PVFHIKLKDQVLLEGEAATLLCLPAACPAPHISWMKDKKSLRSEPSVIIVSCKDGRQLLS 2514
Query: 156 IDEVSIEDVGIYRITVENELGRAEASARLEVITRSGK 192
I G+Y + N LG +S + V GK
Sbjct: 2515 IPRAGKRHAGLYECSATNVLGSITSSCTVAVARVPGK 2551
Score = 33.9 bits (74), Expect = 0.45
Identities = 21/78 (26%), Positives = 31/78 (39%), Gaps = 1/78 (1%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIR-DCADFESSYDDGTARLKIKQVTAEDEGTYT 63
+G+ C P P I W + +R + + S DG L I + G Y
Sbjct: 2468 EGEAATLLCLPAACPAPHISWMKDKKSLRSEPSVIIVSCKDGRQLLSIPRAGKRHAGLYE 2527
Query: 64 CEASNCLGKAKSNACLVV 81
C A+N LG S+ + V
Sbjct: 2528 CSATNVLGSITSSCTVAV 2545
>AB037718-1|BAA92535.1| 2242|Homo sapiens KIAA1297 protein protein.
Length = 2242
Score = 69.7 bits (163), Expect = 7e-12
Identities = 48/182 (26%), Positives = 79/182 (43%), Gaps = 11/182 (6%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCA-DFESSYDDGTARLKIKQVTAEDEGTYTC 64
G+ FEC V G D ++ W +++ + +D +L + V +D G YTC
Sbjct: 1 GEMALFECLVAGPTDVEVDWLCRGRLLQPALLKCKMHFDGRKCKLLLTSVHEDDSGVYTC 60
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
+ S + +A L V + +AP F + V EG F C + G P
Sbjct: 61 KLSTAKDELTCSARLTVRPS---------LAPLFTRLLEDVEVLEGRAARFDCKISGTPP 111
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
P +W G + S + +++ + + L I V ED G+Y ++ N G+A SA+L
Sbjct: 112 PVVTWTHFGCPMEESENLRLRQ-DGGLHSLHIAHVGSEDEGLYAVSAVNTHGQAHCSAQL 170
Query: 185 EV 186
V
Sbjct: 171 YV 172
Score = 68.9 bits (161), Expect = 1e-11
Identities = 52/202 (25%), Positives = 85/202 (42%), Gaps = 21/202 (10%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G F+C+++G P P + W H+ + + + D G L I V +EDEG Y
Sbjct: 96 EGRAARFDCKISGTPPPVVTWTHFGCPMEESENLRLRQDGGLHSLHIAHVGSEDEGLYAV 155
Query: 65 EASNCLGKAKSNACLVVYHTRRLSS-PGRQM--APTFYTYPFNKVVEE------------ 109
A N G+A +A L V R +S P ++ P+ P +E
Sbjct: 156 SAVNTHGQAHCSAQLYVEEPRTAASGPSSKLEKMPSIPEEPEQGELERLSIPDFLRPLQD 215
Query: 110 -----GENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDV 164
+ +C V G P P SW +G I S + + ++ R++ V +
Sbjct: 216 LEVGLAKEAMLECQVTGLPYPTISWFHNGHRIQSSDDRRMTQYRDVHRLV-FPAVGPQHA 274
Query: 165 GIYRITVENELGRAEASARLEV 186
G+Y+ + N+LG+A A L V
Sbjct: 275 GVYKSVIANKLGKAACYAHLYV 296
Score = 53.2 bits (122), Expect = 7e-07
Identities = 46/148 (31%), Positives = 64/148 (43%), Gaps = 14/148 (9%)
Query: 40 SSYDDGTARLKIKQVTAEDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFY 99
S DD L+I +V+ D G TC A N G + C V T L+ AP F
Sbjct: 459 SQPDDDQYCLRICRVSRRDMGALTCTARNRHG---TQTCSV---TLELAE-----APRFE 507
Query: 100 TYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARIT-VKEKEEIMRILEIDE 158
+ + V GE F V+G P P W KD ++T S+ ++ V E+ E L +
Sbjct: 508 SIMEDVEVGAGETARFAVVVEGKPLPDIMWYKDEVLLTESSHVSFVYEENECS--LVVLS 565
Query: 159 VSIEDVGIYRITVENELGRAEASARLEV 186
+D G+Y T +N G A L V
Sbjct: 566 TGAQDGGVYTCTAQNLAGEVSCKAELAV 593
Score = 51.6 bits (118), Expect = 2e-06
Identities = 24/77 (31%), Positives = 36/77 (46%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+T F V G P PDI W+ ++ + + Y++ L + A+D G YTC
Sbjct: 518 GETARFAVVVEGKPLPDIMWYKDEVLLTESSHVSFVYEENECSLVVLSTGAQDGGVYTCT 577
Query: 66 ASNCLGKAKSNACLVVY 82
A N G+ A L V+
Sbjct: 578 AQNLAGEVSCKAELAVH 594
Score = 44.4 bits (100), Expect = 3e-04
Identities = 25/97 (25%), Positives = 41/97 (42%)
Query: 96 PTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILE 155
P F+ ++V+ EGE T C P+P SW KD + + + ++ ++L
Sbjct: 1603 PVFHIKLKDQVLLEGEAATLLCLPAACPAPHISWMKDKKSLRSEPSVIIVSCKDGRQLLS 1662
Query: 156 IDEVSIEDVGIYRITVENELGRAEASARLEVITRSGK 192
I G+Y + N LG +S + V GK
Sbjct: 1663 IPRAGKRHAGLYECSATNVLGSITSSCTVAVARVPGK 1699
Score = 33.9 bits (74), Expect = 0.45
Identities = 21/78 (26%), Positives = 31/78 (39%), Gaps = 1/78 (1%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIR-DCADFESSYDDGTARLKIKQVTAEDEGTYT 63
+G+ C P P I W + +R + + S DG L I + G Y
Sbjct: 1616 EGEAATLLCLPAACPAPHISWMKDKKSLRSEPSVIIVSCKDGRQLLSIPRAGKRHAGLYE 1675
Query: 64 CEASNCLGKAKSNACLVV 81
C A+N LG S+ + V
Sbjct: 1676 CSATNVLGSITSSCTVAV 1693
>X90870-1|CAA62378.1| 458|Homo sapiens myosin-light-chain kinase
protein.
Length = 458
Score = 69.3 bits (162), Expect = 1e-11
Identities = 31/78 (39%), Positives = 45/78 (57%), Gaps = 1/78 (1%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYD-DGTARLKIKQVTAEDEGTYT 63
+G F+C++ G PDP++ WF + IR+ F+ YD DG L I V +D+ YT
Sbjct: 366 EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 425
Query: 64 CEASNCLGKAKSNACLVV 81
C+A N LG+A A L+V
Sbjct: 426 CKAVNSLGEATCTAELIV 443
Score = 42.7 bits (96), Expect = 0.001
Identities = 27/82 (32%), Positives = 34/82 (41%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
V EG F C ++G P P W KD I S + E+ L I +V +D
Sbjct: 364 VVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAK 423
Query: 167 YRITVENELGRAEASARLEVIT 188
Y N LG A +A L V T
Sbjct: 424 YTCKAVNSLGEATCTAELIVET 445
>X85337-1|CAA59685.1| 991|Homo sapiens myosin light chain kinase
protein.
Length = 991
Score = 69.3 bits (162), Expect = 1e-11
Identities = 31/78 (39%), Positives = 45/78 (57%), Gaps = 1/78 (1%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYD-DGTARLKIKQVTAEDEGTYT 63
+G F+C++ G PDP++ WF + IR+ F+ YD DG L I V +D+ YT
Sbjct: 899 EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 958
Query: 64 CEASNCLGKAKSNACLVV 81
C+A N LG+A A L+V
Sbjct: 959 CKAVNSLGEATCTAELIV 976
Score = 44.0 bits (99), Expect = 4e-04
Identities = 24/98 (24%), Positives = 47/98 (47%), Gaps = 1/98 (1%)
Query: 89 SPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKE 148
S + AP F + V EG+ + +C V +P W +G + + I + ++
Sbjct: 169 SESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEG 228
Query: 149 EIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
+ + I++ ED G+Y+ +N+ G+AE S ++ V
Sbjct: 229 SLCSV-SIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 265
Score = 42.7 bits (96), Expect = 0.001
Identities = 27/82 (32%), Positives = 34/82 (41%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
V EG F C ++G P P W KD I S + E+ L I +V +D
Sbjct: 897 VVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAK 956
Query: 167 YRITVENELGRAEASARLEVIT 188
Y N LG A +A L V T
Sbjct: 957 YTCKAVNSLGEATCTAELIVET 978
Score = 38.3 bits (85), Expect = 0.021
Identities = 19/77 (24%), Positives = 35/77 (45%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G + +CQV+ +P I W + ++ S + + I++ ED G Y C
Sbjct: 189 EGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKC 248
Query: 65 EASNCLGKAKSNACLVV 81
A N G+A+ + + V
Sbjct: 249 VAKNDAGQAECSCQVTV 265
Score = 37.9 bits (84), Expect = 0.027
Identities = 28/100 (28%), Positives = 41/100 (41%), Gaps = 1/100 (1%)
Query: 90 PGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEE 149
P M P +P ++ V GE+V V G +W K I S + V+ E
Sbjct: 310 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 369
Query: 150 IMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVITR 189
+ L I E G Y + VEN+ G +A L V+ +
Sbjct: 370 GSK-LTILAGRQEHCGCYTLLVENKSGSRQAQVNLSVVDK 408
>BC113458-1|AAI13459.1| 166|Homo sapiens MYLK protein protein.
Length = 166
Score = 69.3 bits (162), Expect = 1e-11
Identities = 31/78 (39%), Positives = 45/78 (57%), Gaps = 1/78 (1%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYD-DGTARLKIKQVTAEDEGTYT 63
+G F+C++ G PDP++ WF + IR+ F+ YD DG L I V +D+ YT
Sbjct: 74 EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 133
Query: 64 CEASNCLGKAKSNACLVV 81
C+A N LG+A A L+V
Sbjct: 134 CKAVNSLGEATCTAELIV 151
Score = 42.7 bits (96), Expect = 0.001
Identities = 27/82 (32%), Positives = 34/82 (41%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
V EG F C ++G P P W KD I S + E+ L I +V +D
Sbjct: 72 VVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAK 131
Query: 167 YRITVENELGRAEASARLEVIT 188
Y N LG A +A L V T
Sbjct: 132 YTCKAVNSLGEATCTAELIVET 153
>BC113456-1|AAI13457.1| 167|Homo sapiens MYLK protein protein.
Length = 167
Score = 69.3 bits (162), Expect = 1e-11
Identities = 31/78 (39%), Positives = 45/78 (57%), Gaps = 1/78 (1%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYD-DGTARLKIKQVTAEDEGTYT 63
+G F+C++ G PDP++ WF + IR+ F+ YD DG L I V +D+ YT
Sbjct: 75 EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 134
Query: 64 CEASNCLGKAKSNACLVV 81
C+A N LG+A A L+V
Sbjct: 135 CKAVNSLGEATCTAELIV 152
Score = 42.7 bits (96), Expect = 0.001
Identities = 27/82 (32%), Positives = 34/82 (41%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
V EG F C ++G P P W KD I S + E+ L I +V +D
Sbjct: 73 VVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAK 132
Query: 167 YRITVENELGRAEASARLEVIT 188
Y N LG A +A L V T
Sbjct: 133 YTCKAVNSLGEATCTAELIVET 154
>BC107783-1|AAI07784.1| 227|Homo sapiens MYLK protein protein.
Length = 227
Score = 69.3 bits (162), Expect = 1e-11
Identities = 31/78 (39%), Positives = 45/78 (57%), Gaps = 1/78 (1%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYD-DGTARLKIKQVTAEDEGTYT 63
+G F+C++ G PDP++ WF + IR+ F+ YD DG L I V +D+ YT
Sbjct: 135 EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 194
Query: 64 CEASNCLGKAKSNACLVV 81
C+A N LG+A A L+V
Sbjct: 195 CKAVNSLGEATCTAELIV 212
Score = 42.7 bits (96), Expect = 0.001
Identities = 27/82 (32%), Positives = 34/82 (41%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
V EG F C ++G P P W KD I S + E+ L I +V +D
Sbjct: 133 VVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAK 192
Query: 167 YRITVENELGRAEASARLEVIT 188
Y N LG A +A L V T
Sbjct: 193 YTCKAVNSLGEATCTAELIVET 214
>BC100763-1|AAI00764.2| 153|Homo sapiens myosin, light chain kinase
protein.
Length = 153
Score = 69.3 bits (162), Expect = 1e-11
Identities = 31/78 (39%), Positives = 45/78 (57%), Gaps = 1/78 (1%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYD-DGTARLKIKQVTAEDEGTYT 63
+G F+C++ G PDP++ WF + IR+ F+ YD DG L I V +D+ YT
Sbjct: 61 EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 120
Query: 64 CEASNCLGKAKSNACLVV 81
C+A N LG+A A L+V
Sbjct: 121 CKAVNSLGEATCTAELIV 138
Score = 42.7 bits (96), Expect = 0.001
Identities = 27/82 (32%), Positives = 34/82 (41%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
V EG F C ++G P P W KD I S + E+ L I +V +D
Sbjct: 59 VVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAK 118
Query: 167 YRITVENELGRAEASARLEVIT 188
Y N LG A +A L V T
Sbjct: 119 YTCKAVNSLGEATCTAELIVET 140
>BC100762-1|AAI00763.2| 154|Homo sapiens myosin, light chain kinase
protein.
Length = 154
Score = 69.3 bits (162), Expect = 1e-11
Identities = 31/78 (39%), Positives = 45/78 (57%), Gaps = 1/78 (1%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYD-DGTARLKIKQVTAEDEGTYT 63
+G F+C++ G PDP++ WF + IR+ F+ YD DG L I V +D+ YT
Sbjct: 62 EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 121
Query: 64 CEASNCLGKAKSNACLVV 81
C+A N LG+A A L+V
Sbjct: 122 CKAVNSLGEATCTAELIV 139
Score = 42.7 bits (96), Expect = 0.001
Identities = 27/82 (32%), Positives = 34/82 (41%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
V EG F C ++G P P W KD I S + E+ L I +V +D
Sbjct: 60 VVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAK 119
Query: 167 YRITVENELGRAEASARLEVIT 188
Y N LG A +A L V T
Sbjct: 120 YTCKAVNSLGEATCTAELIVET 141
>BC100761-1|AAI00762.2| 154|Homo sapiens myosin, light chain kinase
protein.
Length = 154
Score = 69.3 bits (162), Expect = 1e-11
Identities = 31/78 (39%), Positives = 45/78 (57%), Gaps = 1/78 (1%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYD-DGTARLKIKQVTAEDEGTYT 63
+G F+C++ G PDP++ WF + IR+ F+ YD DG L I V +D+ YT
Sbjct: 62 EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 121
Query: 64 CEASNCLGKAKSNACLVV 81
C+A N LG+A A L+V
Sbjct: 122 CKAVNSLGEATCTAELIV 139
Score = 42.7 bits (96), Expect = 0.001
Identities = 27/82 (32%), Positives = 34/82 (41%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
V EG F C ++G P P W KD I S + E+ L I +V +D
Sbjct: 60 VVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAK 119
Query: 167 YRITVENELGRAEASARLEVIT 188
Y N LG A +A L V T
Sbjct: 120 YTCKAVNSLGEATCTAELIVET 141
>BC064420-1|AAH64420.2| 153|Homo sapiens myosin, light chain kinase
protein.
Length = 153
Score = 69.3 bits (162), Expect = 1e-11
Identities = 31/78 (39%), Positives = 45/78 (57%), Gaps = 1/78 (1%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYD-DGTARLKIKQVTAEDEGTYT 63
+G F+C++ G PDP++ WF + IR+ F+ YD DG L I V +D+ YT
Sbjct: 61 EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 120
Query: 64 CEASNCLGKAKSNACLVV 81
C+A N LG+A A L+V
Sbjct: 121 CKAVNSLGEATCTAELIV 138
Score = 42.7 bits (96), Expect = 0.001
Identities = 27/82 (32%), Positives = 34/82 (41%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
V EG F C ++G P P W KD I S + E+ L I +V +D
Sbjct: 59 VVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAK 118
Query: 167 YRITVENELGRAEASARLEVIT 188
Y N LG A +A L V T
Sbjct: 119 YTCKAVNSLGEATCTAELIVET 140
>BC018128-1|AAH18128.1| 820|Homo sapiens fibroblast growth factor
receptor 1 (fms-related tyrosine kinase 2, Pfeiffer sy
protein.
Length = 820
Score = 69.3 bits (162), Expect = 1e-11
Identities = 59/197 (29%), Positives = 83/197 (42%), Gaps = 27/197 (13%)
Query: 8 TVEFECQVTGNPDPDIRWFHYAEVIRD---CADFESSYDDGTARLKIKQVTAEDEGTYTC 64
TV+F+C +G P+P +RW + + ++ Y G+ + + V D+G YTC
Sbjct: 171 TVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATGS--IIMDSVVPSDKGNYTC 228
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
N G L V SP R + P NK V G NV F C V +P
Sbjct: 229 IVENEYGSINHTYQLDVVER----SPHRPILQA--GLPANKTVALGSNVEFMCKVYSDPQ 282
Query: 125 PWASWDK----DGSIITP----------SARITVKEKEEIMRILEIDEVSIEDVGIYRIT 170
P W K +GS I P +A + +KE M +L + VS ED G Y
Sbjct: 283 PHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKE--MEVLHLRNVSFEDAGEYTCL 340
Query: 171 VENELGRAEASARLEVI 187
N +G + SA L V+
Sbjct: 341 AGNSIGLSHHSAWLTVL 357
Score = 48.8 bits (111), Expect = 1e-05
Identities = 28/84 (33%), Positives = 38/84 (45%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
V + V FKC G P+P W K+G P RI + + +D V D G
Sbjct: 166 VPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATGSIIMDSVVPSDKGN 225
Query: 167 YRITVENELGRAEASARLEVITRS 190
Y VENE G + +L+V+ RS
Sbjct: 226 YTCIVENEYGSINHTYQLDVVERS 249
Score = 41.1 bits (92), Expect = 0.003
Identities = 29/90 (32%), Positives = 41/90 (45%), Gaps = 15/90 (16%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEV--------------IRDCADFESSYDDGTARLKI 51
G VEF C+V +P P I+W + EV I A ++ D L +
Sbjct: 268 GSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTT-DKEMEVLHL 326
Query: 52 KQVTAEDEGTYTCEASNCLGKAKSNACLVV 81
+ V+ ED G YTC A N +G + +A L V
Sbjct: 327 RNVSFEDAGEYTCLAGNSIGLSHHSAWLTV 356
>BC017811-1|AAH17811.1| 236|Homo sapiens MYLK protein protein.
Length = 236
Score = 69.3 bits (162), Expect = 1e-11
Identities = 31/78 (39%), Positives = 45/78 (57%), Gaps = 1/78 (1%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYD-DGTARLKIKQVTAEDEGTYT 63
+G F+C++ G PDP++ WF + IR+ F+ YD DG L I V +D+ YT
Sbjct: 134 EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 193
Query: 64 CEASNCLGKAKSNACLVV 81
C+A N LG+A A L+V
Sbjct: 194 CKAVNSLGEATCTAELIV 211
Score = 42.7 bits (96), Expect = 0.001
Identities = 27/82 (32%), Positives = 34/82 (41%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
V EG F C ++G P P W KD I S + E+ L I +V +D
Sbjct: 132 VVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAK 191
Query: 167 YRITVENELGRAEASARLEVIT 188
Y N LG A +A L V T
Sbjct: 192 YTCKAVNSLGEATCTAELIVET 213
>AF096775-1|AAD54019.1| 154|Homo sapiens kinase-related protein
isoform 2 protein.
Length = 154
Score = 69.3 bits (162), Expect = 1e-11
Identities = 31/78 (39%), Positives = 45/78 (57%), Gaps = 1/78 (1%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYD-DGTARLKIKQVTAEDEGTYT 63
+G F+C++ G PDP++ WF + IR+ F+ YD DG L I V +D+ YT
Sbjct: 62 EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 121
Query: 64 CEASNCLGKAKSNACLVV 81
C+A N LG+A A L+V
Sbjct: 122 CKAVNSLGEATCTAELIV 139
Score = 42.7 bits (96), Expect = 0.001
Identities = 27/82 (32%), Positives = 34/82 (41%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
V EG F C ++G P P W KD I S + E+ L I +V +D
Sbjct: 60 VVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAK 119
Query: 167 YRITVENELGRAEASARLEVIT 188
Y N LG A +A L V T
Sbjct: 120 YTCKAVNSLGEATCTAELIVET 141
>AF096774-1|AAD54018.1| 153|Homo sapiens kinase-related protein
isoform 1 protein.
Length = 153
Score = 69.3 bits (162), Expect = 1e-11
Identities = 31/78 (39%), Positives = 45/78 (57%), Gaps = 1/78 (1%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYD-DGTARLKIKQVTAEDEGTYT 63
+G F+C++ G PDP++ WF + IR+ F+ YD DG L I V +D+ YT
Sbjct: 61 EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 120
Query: 64 CEASNCLGKAKSNACLVV 81
C+A N LG+A A L+V
Sbjct: 121 CKAVNSLGEATCTAELIV 138
Score = 42.7 bits (96), Expect = 0.001
Identities = 27/82 (32%), Positives = 34/82 (41%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
V EG F C ++G P P W KD I S + E+ L I +V +D
Sbjct: 59 VVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAK 118
Query: 167 YRITVENELGRAEASARLEVIT 188
Y N LG A +A L V T
Sbjct: 119 YTCKAVNSLGEATCTAELIVET 140
>AF096773-1|AAD54017.1| 154|Homo sapiens kinase-related protein
protein.
Length = 154
Score = 69.3 bits (162), Expect = 1e-11
Identities = 31/78 (39%), Positives = 45/78 (57%), Gaps = 1/78 (1%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYD-DGTARLKIKQVTAEDEGTYT 63
+G F+C++ G PDP++ WF + IR+ F+ YD DG L I V +D+ YT
Sbjct: 62 EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 121
Query: 64 CEASNCLGKAKSNACLVV 81
C+A N LG+A A L+V
Sbjct: 122 CKAVNSLGEATCTAELIV 139
Score = 42.7 bits (96), Expect = 0.001
Identities = 27/82 (32%), Positives = 34/82 (41%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
V EG F C ++G P P W KD I S + E+ L I +V +D
Sbjct: 60 VVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAK 119
Query: 167 YRITVENELGRAEASARLEVIT 188
Y N LG A +A L V T
Sbjct: 120 YTCKAVNSLGEATCTAELIVET 141
>AF096771-2|AAD51381.1| 153|Homo sapiens kinase related protein
protein.
Length = 153
Score = 69.3 bits (162), Expect = 1e-11
Identities = 31/78 (39%), Positives = 45/78 (57%), Gaps = 1/78 (1%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYD-DGTARLKIKQVTAEDEGTYT 63
+G F+C++ G PDP++ WF + IR+ F+ YD DG L I V +D+ YT
Sbjct: 61 EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 120
Query: 64 CEASNCLGKAKSNACLVV 81
C+A N LG+A A L+V
Sbjct: 121 CKAVNSLGEATCTAELIV 138
Score = 42.7 bits (96), Expect = 0.001
Identities = 27/82 (32%), Positives = 34/82 (41%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
V EG F C ++G P P W KD I S + E+ L I +V +D
Sbjct: 59 VVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAK 118
Query: 167 YRITVENELGRAEASARLEVIT 188
Y N LG A +A L V T
Sbjct: 119 YTCKAVNSLGEATCTAELIVET 140
>AF096771-1|AAD51380.1| 300|Homo sapiens smooth muscle/nonmuscle
myosin light chain kinase protein.
Length = 300
Score = 69.3 bits (162), Expect = 1e-11
Identities = 31/78 (39%), Positives = 45/78 (57%), Gaps = 1/78 (1%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYD-DGTARLKIKQVTAEDEGTYT 63
+G F+C++ G PDP++ WF + IR+ F+ YD DG L I V +D+ YT
Sbjct: 208 EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 267
Query: 64 CEASNCLGKAKSNACLVV 81
C+A N LG+A A L+V
Sbjct: 268 CKAVNSLGEATCTAELIV 285
Score = 42.7 bits (96), Expect = 0.001
Identities = 27/82 (32%), Positives = 34/82 (41%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
V EG F C ++G P P W KD I S + E+ L I +V +D
Sbjct: 206 VVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAK 265
Query: 167 YRITVENELGRAEASARLEVIT 188
Y N LG A +A L V T
Sbjct: 266 YTCKAVNSLGEATCTAELIVET 287
>AB037663-1|BAB21504.1| 992|Homo sapiens myosin light chain kinase
protein.
Length = 992
Score = 69.3 bits (162), Expect = 1e-11
Identities = 31/78 (39%), Positives = 45/78 (57%), Gaps = 1/78 (1%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYD-DGTARLKIKQVTAEDEGTYT 63
+G F+C++ G PDP++ WF + IR+ F+ YD DG L I V +D+ YT
Sbjct: 900 EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 959
Query: 64 CEASNCLGKAKSNACLVV 81
C+A N LG+A A L+V
Sbjct: 960 CKAVNSLGEATCTAELIV 977
Score = 44.0 bits (99), Expect = 4e-04
Identities = 24/98 (24%), Positives = 47/98 (47%), Gaps = 1/98 (1%)
Query: 89 SPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKE 148
S + AP F + V EG+ + +C V +P W +G + + I + ++
Sbjct: 169 SESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEG 228
Query: 149 EIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
+ + I++ ED G+Y+ +N+ G+AE S ++ V
Sbjct: 229 SLCSV-SIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 265
Score = 42.7 bits (96), Expect = 0.001
Identities = 27/82 (32%), Positives = 34/82 (41%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
V EG F C ++G P P W KD I S + E+ L I +V +D
Sbjct: 898 VVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAK 957
Query: 167 YRITVENELGRAEASARLEVIT 188
Y N LG A +A L V T
Sbjct: 958 YTCKAVNSLGEATCTAELIVET 979
Score = 41.1 bits (92), Expect = 0.003
Identities = 29/100 (29%), Positives = 42/100 (42%), Gaps = 1/100 (1%)
Query: 90 PGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEE 149
P M P +P ++ V GE+V V G +W K I S + V+ E
Sbjct: 310 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 369
Query: 150 IMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVITR 189
+ L I E G Y + VEN+LG +A L V+ +
Sbjct: 370 GSK-LTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 408
Score = 38.3 bits (85), Expect = 0.021
Identities = 19/77 (24%), Positives = 35/77 (45%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G + +CQV+ +P I W + ++ S + + I++ ED G Y C
Sbjct: 189 EGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKC 248
Query: 65 EASNCLGKAKSNACLVV 81
A N G+A+ + + V
Sbjct: 249 VAKNDAGQAECSCQVTV 265
>BC117674-1|AAI17675.2| 1240|Homo sapiens NFASC protein protein.
Length = 1240
Score = 68.9 bits (161), Expect = 1e-11
Identities = 54/178 (30%), Positives = 82/178 (46%), Gaps = 20/178 (11%)
Query: 12 ECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLG 71
+C G+P P +RWF + Y++G+ L+IK + ED+G YTC A+N LG
Sbjct: 451 DCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGS--LEIKMIRKEDQGIYTCVATNILG 508
Query: 72 KAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS--PWASW 129
KA++ L V R+ Y P ++V G V +C VK +PS SW
Sbjct: 509 KAENQVRLEVKDPTRI-----------YRMPEDQVARRGTTVQLECRVKHDPSLKLTVSW 557
Query: 130 DKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVI 187
KD + R +K++++ + I + E D G Y EL + A A L V+
Sbjct: 558 LKDDEPLYIGNR--MKKEDDSLTIFGVAE---RDQGSYTCVASTELDQDLAKAYLTVL 610
Score = 59.7 bits (138), Expect = 8e-09
Identities = 44/176 (25%), Positives = 72/176 (40%), Gaps = 16/176 (9%)
Query: 12 ECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLG 71
EC +G P PDI W+ D ++ +++ L+I V+ ED G Y C ASN +G
Sbjct: 267 ECIASGVPTPDIAWYKKGG---DLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMG 323
Query: 72 KAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDK 131
+ + V + AP + P N ++ GE+ C GNP P W
Sbjct: 324 SIRHTISVRV-----------KAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMV 372
Query: 132 DGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVI 187
+G + + +E + + I +Y+ NE G A+A + V+
Sbjct: 373 NGEPLQSAP--PNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVL 426
Score = 50.4 bits (115), Expect = 5e-06
Identities = 48/188 (25%), Positives = 69/188 (36%), Gaps = 17/188 (9%)
Query: 1 MLSCDGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEG 60
++ G+ C+ GNP P ++W E ++ + G + +
Sbjct: 346 LILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDT-IIFRDTQISSRA 404
Query: 61 TYTCEASNCLGKAKSNACLVVYHT-RRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAV 119
Y C SN G +NA + V R+ SP Q+ +N+ C
Sbjct: 405 VYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVIL---YNR-------TRLDCPF 454
Query: 120 KGNPSPWASWDKDG-SIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRA 178
G+P P W K+G V E LEI + ED GIY N LG+A
Sbjct: 455 FGSPIPTLRWFKNGQGSNLDGGNYHVYENGS----LEIKMIRKEDQGIYTCVATNILGKA 510
Query: 179 EASARLEV 186
E RLEV
Sbjct: 511 ENQVRLEV 518
Score = 38.7 bits (86), Expect = 0.016
Identities = 37/128 (28%), Positives = 47/128 (36%), Gaps = 14/128 (10%)
Query: 7 DTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSY--DDGTARLKIKQ--VTAEDEGTY 62
D + EC+ GNP P W + D S GT + + E EG Y
Sbjct: 57 DNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEY 116
Query: 63 TCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKC-AVKG 121
C A N G A SN + L P + P VV+EG +T +C G
Sbjct: 117 QCFARNKFGTALSNRIRLQVSKSPL-WPKENLDPV--------VVQEGAPLTLQCNPPPG 167
Query: 122 NPSPWASW 129
PSP W
Sbjct: 168 LPSPVIFW 175
Score = 34.7 bits (76), Expect = 0.26
Identities = 22/73 (30%), Positives = 36/73 (49%), Gaps = 4/73 (5%)
Query: 104 NKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIED 163
+++V G ++ +C G P+P +W K G + PS + + E + L I VS ED
Sbjct: 255 SQMVLRGMDLLLECIASGVPTPDIAWYKKGGDL-PSDK---AKFENFNKALRITNVSEED 310
Query: 164 VGIYRITVENELG 176
G Y N++G
Sbjct: 311 SGEYFCLASNKMG 323
Score = 31.9 bits (69), Expect = 1.8
Identities = 21/85 (24%), Positives = 40/85 (47%), Gaps = 4/85 (4%)
Query: 106 VVEEGENVTFKCAVKGNPSPWASWDKDGSI--ITPSARITVKEKEEIMRI-LEIDEVSIE 162
+V+ +N+ +C KGNP+P W ++ I R++++ + + I E
Sbjct: 52 IVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEE 111
Query: 163 DVGIYRITVENELGRAEAS-ARLEV 186
G Y+ N+ G A ++ RL+V
Sbjct: 112 YEGEYQCFARNKFGTALSNRIRLQV 136
>BC008124-1|AAH08124.2| 294|Homo sapiens NFASC protein protein.
Length = 294
Score = 68.9 bits (161), Expect = 1e-11
Identities = 54/178 (30%), Positives = 82/178 (46%), Gaps = 20/178 (11%)
Query: 12 ECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLG 71
+C G+P P +RWF + Y++G+ L+IK + ED+G YTC A+N LG
Sbjct: 126 DCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGS--LEIKMIRKEDQGIYTCVATNILG 183
Query: 72 KAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS--PWASW 129
KA++ L V R+ Y P ++V G V +C VK +PS SW
Sbjct: 184 KAENQVRLEVKDPTRI-----------YRMPEDQVARRGTTVQLECRVKHDPSLKLTVSW 232
Query: 130 DKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVI 187
KD + R +K++++ + I + E D G Y EL + A A L V+
Sbjct: 233 LKDDEPLYIGNR--MKKEDDSLTIFGVAE---RDQGSYTCVASTELDQDLAKAYLTVL 285
Score = 50.4 bits (115), Expect = 5e-06
Identities = 48/188 (25%), Positives = 69/188 (36%), Gaps = 17/188 (9%)
Query: 1 MLSCDGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEG 60
++ G+ C+ GNP P ++W E ++ + G + +
Sbjct: 21 LILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDT-IIFRDTQISSRA 79
Query: 61 TYTCEASNCLGKAKSNACLVVYHT-RRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAV 119
Y C SN G +NA + V R+ SP Q+ +N+ C
Sbjct: 80 VYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVIL---YNR-------TRLDCPF 129
Query: 120 KGNPSPWASWDKDG-SIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRA 178
G+P P W K+G V E LEI + ED GIY N LG+A
Sbjct: 130 FGSPIPTLRWFKNGQGSNLDGGNYHVYENGS----LEIKMIRKEDQGIYTCVATNILGKA 185
Query: 179 EASARLEV 186
E RLEV
Sbjct: 186 ENQVRLEV 193
Score = 34.3 bits (75), Expect = 0.34
Identities = 22/93 (23%), Positives = 37/93 (39%), Gaps = 2/93 (2%)
Query: 95 APTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRIL 154
AP + P N ++ GE+ C GNP P W +G + + +E +
Sbjct: 11 APYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAP--PNPNREVAGDTI 68
Query: 155 EIDEVSIEDVGIYRITVENELGRAEASARLEVI 187
+ I +Y+ NE G A+A + V+
Sbjct: 69 IFRDTQISSRAVYQCNTSNEHGYLLANAFVSVL 101
>AY730707-1|AAU44786.1| 1093|Homo sapiens leucine-rich repeat
protein LRIG1 protein.
Length = 1093
Score = 68.9 bits (161), Expect = 1e-11
Identities = 53/183 (28%), Positives = 75/183 (40%), Gaps = 19/183 (10%)
Query: 12 ECQVTGNPDPDIRWFHYAEVIRDCADFESSY---DDGTARLKIKQVTAEDEGTYTCEASN 68
EC TG+P+P I W A + DD I V +D G Y+C A N
Sbjct: 619 ECAATGHPNPQIAWQKDGGTDFPAARERRMHVMPDDDV--FFITDVKIDDAGVYSCTAQN 676
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G +NA L V T L P ++VV GE V +C GNP P +
Sbjct: 677 SAGSISANATLTVLETPSLVVPLE-----------DRVVSVGETVALQCKATGNPPPRIT 725
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVIT 188
W K ++ + R + + +L + V ED G Y + N LG A ++L V+
Sbjct: 726 WFKGDRPLSLTERHHLTPDNQ---LLVVQNVVAEDAGRYTCEMSNTLGTERAHSQLSVLP 782
Query: 189 RSG 191
+G
Sbjct: 783 AAG 785
Score = 66.5 bits (155), Expect = 7e-11
Identities = 43/142 (30%), Positives = 63/142 (44%), Gaps = 10/142 (7%)
Query: 46 TARLKIKQVTAEDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNK 105
T L ++QVT EG Y C +N G S H RL+ + P+F P +
Sbjct: 559 TTILHLRQVTFGHEGRYQCVITNHFGSTYS-------HKARLTV---NVLPSFTKTPHDI 608
Query: 106 VVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVG 165
+ +CA G+P+P +W KDG P+AR + I +V I+D G
Sbjct: 609 TIRTTTVARLECAATGHPNPQIAWQKDGGTDFPAARERRMHVMPDDDVFFITDVKIDDAG 668
Query: 166 IYRITVENELGRAEASARLEVI 187
+Y T +N G A+A L V+
Sbjct: 669 VYSCTAQNSAGSISANATLTVL 690
Score = 54.8 bits (126), Expect = 2e-07
Identities = 29/76 (38%), Positives = 41/76 (53%), Gaps = 2/76 (2%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+TV +C+ TGNP P I WF + + D+ L ++ V AED G YTCE
Sbjct: 707 GETVALQCKATGNPPPRITWFKGDRPLSLTERHHLTPDNQL--LVVQNVVAEDAGRYTCE 764
Query: 66 ASNCLGKAKSNACLVV 81
SN LG ++++ L V
Sbjct: 765 MSNTLGTERAHSQLSV 780
>AL391822-8|CAI14664.1| 1040|Homo sapiens neurofascin homolog
(chicken) protein.
Length = 1040
Score = 68.9 bits (161), Expect = 1e-11
Identities = 54/178 (30%), Positives = 82/178 (46%), Gaps = 20/178 (11%)
Query: 12 ECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLG 71
+C G+P P +RWF + Y++G+ L+IK + ED+G YTC A+N LG
Sbjct: 420 DCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGS--LEIKMIRKEDQGIYTCVATNILG 477
Query: 72 KAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS--PWASW 129
KA++ L V R+ Y P ++V G V +C VK +PS SW
Sbjct: 478 KAENQVRLEVKDPTRI-----------YRMPEDQVARRGTTVQLECRVKHDPSLKLTVSW 526
Query: 130 DKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVI 187
KD + R +K++++ + I + E D G Y EL + A A L V+
Sbjct: 527 LKDDEPLYIGNR--MKKEDDSLTIFGVAE---RDQGSYTCVASTELDQDLAKAYLTVL 579
Score = 59.7 bits (138), Expect = 8e-09
Identities = 44/176 (25%), Positives = 72/176 (40%), Gaps = 16/176 (9%)
Query: 12 ECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLG 71
EC +G P PDI W+ D ++ +++ L+I V+ ED G Y C ASN +G
Sbjct: 236 ECIASGVPTPDIAWYKKGG---DLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMG 292
Query: 72 KAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDK 131
+ + V + AP + P N ++ GE+ C GNP P W
Sbjct: 293 SIRHTISVRV-----------KAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMV 341
Query: 132 DGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVI 187
+G + + +E + + I +Y+ NE G A+A + V+
Sbjct: 342 NGEPLQSAP--PNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVL 395
Score = 50.4 bits (115), Expect = 5e-06
Identities = 48/188 (25%), Positives = 69/188 (36%), Gaps = 17/188 (9%)
Query: 1 MLSCDGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEG 60
++ G+ C+ GNP P ++W E ++ + G + +
Sbjct: 315 LILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDT-IIFRDTQISSRA 373
Query: 61 TYTCEASNCLGKAKSNACLVVYHT-RRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAV 119
Y C SN G +NA + V R+ SP Q+ +N+ C
Sbjct: 374 VYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVIL---YNR-------TRLDCPF 423
Query: 120 KGNPSPWASWDKDG-SIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRA 178
G+P P W K+G V E LEI + ED GIY N LG+A
Sbjct: 424 FGSPIPTLRWFKNGQGSNLDGGNYHVYENGS----LEIKMIRKEDQGIYTCVATNILGKA 479
Query: 179 EASARLEV 186
E RLEV
Sbjct: 480 ENQVRLEV 487
Score = 38.7 bits (86), Expect = 0.016
Identities = 37/128 (28%), Positives = 47/128 (36%), Gaps = 14/128 (10%)
Query: 7 DTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSY--DDGTARLKIKQ--VTAEDEGTY 62
D + EC+ GNP P W + D S GT + + E EG Y
Sbjct: 26 DNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEY 85
Query: 63 TCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKC-AVKG 121
C A N G A SN + L P + P VV+EG +T +C G
Sbjct: 86 QCFARNKFGTALSNRIRLQVSKSPL-WPKENLDPV--------VVQEGAPLTLQCNPPPG 136
Query: 122 NPSPWASW 129
PSP W
Sbjct: 137 LPSPVIFW 144
Score = 34.7 bits (76), Expect = 0.26
Identities = 22/73 (30%), Positives = 36/73 (49%), Gaps = 4/73 (5%)
Query: 104 NKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIED 163
+++V G ++ +C G P+P +W K G + PS + + E + L I VS ED
Sbjct: 224 SQMVLRGMDLLLECIASGVPTPDIAWYKKGGDL-PSDK---AKFENFNKALRITNVSEED 279
Query: 164 VGIYRITVENELG 176
G Y N++G
Sbjct: 280 SGEYFCLASNKMG 292
Score = 31.9 bits (69), Expect = 1.8
Identities = 21/85 (24%), Positives = 40/85 (47%), Gaps = 4/85 (4%)
Query: 106 VVEEGENVTFKCAVKGNPSPWASWDKDGSI--ITPSARITVKEKEEIMRI-LEIDEVSIE 162
+V+ +N+ +C KGNP+P W ++ I R++++ + + I E
Sbjct: 21 IVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEE 80
Query: 163 DVGIYRITVENELGRAEAS-ARLEV 186
G Y+ N+ G A ++ RL+V
Sbjct: 81 YEGEYQCFARNKFGTALSNRIRLQV 105
>AL391822-7|CAI14662.1| 1165|Homo sapiens neurofascin homolog
(chicken) protein.
Length = 1165
Score = 68.9 bits (161), Expect = 1e-11
Identities = 54/178 (30%), Positives = 82/178 (46%), Gaps = 20/178 (11%)
Query: 12 ECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLG 71
+C G+P P +RWF + Y++G+ L+IK + ED+G YTC A+N LG
Sbjct: 438 DCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGS--LEIKMIRKEDQGIYTCVATNILG 495
Query: 72 KAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS--PWASW 129
KA++ L V R+ Y P ++V G V +C VK +PS SW
Sbjct: 496 KAENQVRLEVKDPTRI-----------YRMPEDQVARRGTTVQLECRVKHDPSLKLTVSW 544
Query: 130 DKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVI 187
KD + R +K++++ + I + E D G Y EL + A A L V+
Sbjct: 545 LKDDEPLYIGNR--MKKEDDSLTIFGVAE---RDQGSYTCVASTELDQDLAKAYLTVL 597
Score = 59.7 bits (138), Expect = 8e-09
Identities = 44/176 (25%), Positives = 72/176 (40%), Gaps = 16/176 (9%)
Query: 12 ECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLG 71
EC +G P PDI W+ D ++ +++ L+I V+ ED G Y C ASN +G
Sbjct: 254 ECIASGVPTPDIAWYKKGG---DLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMG 310
Query: 72 KAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDK 131
+ + V + AP + P N ++ GE+ C GNP P W
Sbjct: 311 SIRHTISVRV-----------KAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMV 359
Query: 132 DGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVI 187
+G + + +E + + I +Y+ NE G A+A + V+
Sbjct: 360 NGEPLQSAP--PNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVL 413
Score = 50.4 bits (115), Expect = 5e-06
Identities = 48/188 (25%), Positives = 69/188 (36%), Gaps = 17/188 (9%)
Query: 1 MLSCDGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEG 60
++ G+ C+ GNP P ++W E ++ + G + +
Sbjct: 333 LILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDT-IIFRDTQISSRA 391
Query: 61 TYTCEASNCLGKAKSNACLVVYHT-RRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAV 119
Y C SN G +NA + V R+ SP Q+ +N+ C
Sbjct: 392 VYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVIL---YNR-------TRLDCPF 441
Query: 120 KGNPSPWASWDKDG-SIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRA 178
G+P P W K+G V E LEI + ED GIY N LG+A
Sbjct: 442 FGSPIPTLRWFKNGQGSNLDGGNYHVYENGS----LEIKMIRKEDQGIYTCVATNILGKA 497
Query: 179 EASARLEV 186
E RLEV
Sbjct: 498 ENQVRLEV 505
Score = 38.7 bits (86), Expect = 0.016
Identities = 37/128 (28%), Positives = 47/128 (36%), Gaps = 14/128 (10%)
Query: 7 DTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSY--DDGTARLKIKQ--VTAEDEGTY 62
D + EC+ GNP P W + D S GT + + E EG Y
Sbjct: 27 DNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEY 86
Query: 63 TCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKC-AVKG 121
C A N G A SN + L P + P VV+EG +T +C G
Sbjct: 87 QCFARNKFGTALSNRIRLQVSKSPL-WPKENLDPV--------VVQEGAPLTLQCNPPPG 137
Query: 122 NPSPWASW 129
PSP W
Sbjct: 138 LPSPVIFW 145
Score = 34.7 bits (76), Expect = 0.26
Identities = 22/73 (30%), Positives = 36/73 (49%), Gaps = 4/73 (5%)
Query: 104 NKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIED 163
+++V G ++ +C G P+P +W K G + PS + + E + L I VS ED
Sbjct: 242 SQMVLRGMDLLLECIASGVPTPDIAWYKKGGDL-PSDK---AKFENFNKALRITNVSEED 297
Query: 164 VGIYRITVENELG 176
G Y N++G
Sbjct: 298 SGEYFCLASNKMG 310
Score = 31.9 bits (69), Expect = 1.8
Identities = 21/85 (24%), Positives = 40/85 (47%), Gaps = 4/85 (4%)
Query: 106 VVEEGENVTFKCAVKGNPSPWASWDKDGSI--ITPSARITVKEKEEIMRI-LEIDEVSIE 162
+V+ +N+ +C KGNP+P W ++ I R++++ + + I E
Sbjct: 22 IVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEE 81
Query: 163 DVGIYRITVENELGRAEAS-ARLEV 186
G Y+ N+ G A ++ RL+V
Sbjct: 82 YEGEYQCFARNKFGTALSNRIRLQV 106
>AL391822-5|CAI14659.1| 1240|Homo sapiens neurofascin homolog
(chicken) protein.
Length = 1240
Score = 68.9 bits (161), Expect = 1e-11
Identities = 54/178 (30%), Positives = 82/178 (46%), Gaps = 20/178 (11%)
Query: 12 ECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLG 71
+C G+P P +RWF + Y++G+ L+IK + ED+G YTC A+N LG
Sbjct: 451 DCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGS--LEIKMIRKEDQGIYTCVATNILG 508
Query: 72 KAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS--PWASW 129
KA++ L V R+ Y P ++V G V +C VK +PS SW
Sbjct: 509 KAENQVRLEVKDPTRI-----------YRMPEDQVARRGTTVQLECRVKHDPSLKLTVSW 557
Query: 130 DKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVI 187
KD + R +K++++ + I + E D G Y EL + A A L V+
Sbjct: 558 LKDDEPLYIGNR--MKKEDDSLTIFGVAE---RDQGSYTCVASTELDQDLAKAYLTVL 610
Score = 59.7 bits (138), Expect = 8e-09
Identities = 44/176 (25%), Positives = 72/176 (40%), Gaps = 16/176 (9%)
Query: 12 ECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLG 71
EC +G P PDI W+ D ++ +++ L+I V+ ED G Y C ASN +G
Sbjct: 267 ECIASGVPTPDIAWYKKGG---DLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMG 323
Query: 72 KAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDK 131
+ + V + AP + P N ++ GE+ C GNP P W
Sbjct: 324 SIRHTISVRV-----------KAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMV 372
Query: 132 DGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVI 187
+G + + +E + + I +Y+ NE G A+A + V+
Sbjct: 373 NGEPLQSAP--PNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVL 426
Score = 50.4 bits (115), Expect = 5e-06
Identities = 48/188 (25%), Positives = 69/188 (36%), Gaps = 17/188 (9%)
Query: 1 MLSCDGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEG 60
++ G+ C+ GNP P ++W E ++ + G + +
Sbjct: 346 LILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDT-IIFRDTQISSRA 404
Query: 61 TYTCEASNCLGKAKSNACLVVYHT-RRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAV 119
Y C SN G +NA + V R+ SP Q+ +N+ C
Sbjct: 405 VYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVIL---YNR-------TRLDCPF 454
Query: 120 KGNPSPWASWDKDG-SIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRA 178
G+P P W K+G V E LEI + ED GIY N LG+A
Sbjct: 455 FGSPIPTLRWFKNGQGSNLDGGNYHVYENGS----LEIKMIRKEDQGIYTCVATNILGKA 510
Query: 179 EASARLEV 186
E RLEV
Sbjct: 511 ENQVRLEV 518
Score = 38.7 bits (86), Expect = 0.016
Identities = 37/128 (28%), Positives = 47/128 (36%), Gaps = 14/128 (10%)
Query: 7 DTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSY--DDGTARLKIKQ--VTAEDEGTY 62
D + EC+ GNP P W + D S GT + + E EG Y
Sbjct: 57 DNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEY 116
Query: 63 TCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKC-AVKG 121
C A N G A SN + L P + P VV+EG +T +C G
Sbjct: 117 QCFARNKFGTALSNRIRLQVSKSPL-WPKENLDPV--------VVQEGAPLTLQCNPPPG 167
Query: 122 NPSPWASW 129
PSP W
Sbjct: 168 LPSPVIFW 175
Score = 34.7 bits (76), Expect = 0.26
Identities = 22/73 (30%), Positives = 36/73 (49%), Gaps = 4/73 (5%)
Query: 104 NKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIED 163
+++V G ++ +C G P+P +W K G + PS + + E + L I VS ED
Sbjct: 255 SQMVLRGMDLLLECIASGVPTPDIAWYKKGGDL-PSDK---AKFENFNKALRITNVSEED 310
Query: 164 VGIYRITVENELG 176
G Y N++G
Sbjct: 311 SGEYFCLASNKMG 323
Score = 31.9 bits (69), Expect = 1.8
Identities = 21/85 (24%), Positives = 40/85 (47%), Gaps = 4/85 (4%)
Query: 106 VVEEGENVTFKCAVKGNPSPWASWDKDGSI--ITPSARITVKEKEEIMRI-LEIDEVSIE 162
+V+ +N+ +C KGNP+P W ++ I R++++ + + I E
Sbjct: 52 IVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEE 111
Query: 163 DVGIYRITVENELGRAEAS-ARLEV 186
G Y+ N+ G A ++ RL+V
Sbjct: 112 YEGEYQCFARNKFGTALSNRIRLQV 136
>AL391822-4|CAI14660.1| 1347|Homo sapiens neurofascin homolog
(chicken) protein.
Length = 1347
Score = 68.9 bits (161), Expect = 1e-11
Identities = 54/178 (30%), Positives = 82/178 (46%), Gaps = 20/178 (11%)
Query: 12 ECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLG 71
+C G+P P +RWF + Y++G+ L+IK + ED+G YTC A+N LG
Sbjct: 451 DCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGS--LEIKMIRKEDQGIYTCVATNILG 508
Query: 72 KAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS--PWASW 129
KA++ L V R+ Y P ++V G V +C VK +PS SW
Sbjct: 509 KAENQVRLEVKDPTRI-----------YRMPEDQVARRGTTVQLECRVKHDPSLKLTVSW 557
Query: 130 DKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVI 187
KD + R +K++++ + I + E D G Y EL + A A L V+
Sbjct: 558 LKDDEPLYIGNR--MKKEDDSLTIFGVAE---RDQGSYTCVASTELDQDLAKAYLTVL 610
Score = 59.7 bits (138), Expect = 8e-09
Identities = 44/176 (25%), Positives = 72/176 (40%), Gaps = 16/176 (9%)
Query: 12 ECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLG 71
EC +G P PDI W+ D ++ +++ L+I V+ ED G Y C ASN +G
Sbjct: 267 ECIASGVPTPDIAWYKKGG---DLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMG 323
Query: 72 KAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDK 131
+ + V + AP + P N ++ GE+ C GNP P W
Sbjct: 324 SIRHTISVRV-----------KAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMV 372
Query: 132 DGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVI 187
+G + + +E + + I +Y+ NE G A+A + V+
Sbjct: 373 NGEPLQSAP--PNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVL 426
Score = 50.4 bits (115), Expect = 5e-06
Identities = 48/188 (25%), Positives = 69/188 (36%), Gaps = 17/188 (9%)
Query: 1 MLSCDGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEG 60
++ G+ C+ GNP P ++W E ++ + G + +
Sbjct: 346 LILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDT-IIFRDTQISSRA 404
Query: 61 TYTCEASNCLGKAKSNACLVVYHT-RRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAV 119
Y C SN G +NA + V R+ SP Q+ +N+ C
Sbjct: 405 VYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVIL---YNR-------TRLDCPF 454
Query: 120 KGNPSPWASWDKDG-SIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRA 178
G+P P W K+G V E LEI + ED GIY N LG+A
Sbjct: 455 FGSPIPTLRWFKNGQGSNLDGGNYHVYENGS----LEIKMIRKEDQGIYTCVATNILGKA 510
Query: 179 EASARLEV 186
E RLEV
Sbjct: 511 ENQVRLEV 518
Score = 38.7 bits (86), Expect = 0.016
Identities = 37/128 (28%), Positives = 47/128 (36%), Gaps = 14/128 (10%)
Query: 7 DTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSY--DDGTARLKIKQ--VTAEDEGTY 62
D + EC+ GNP P W + D S GT + + E EG Y
Sbjct: 57 DNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEY 116
Query: 63 TCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKC-AVKG 121
C A N G A SN + L P + P VV+EG +T +C G
Sbjct: 117 QCFARNKFGTALSNRIRLQVSKSPL-WPKENLDPV--------VVQEGAPLTLQCNPPPG 167
Query: 122 NPSPWASW 129
PSP W
Sbjct: 168 LPSPVIFW 175
Score = 34.7 bits (76), Expect = 0.26
Identities = 22/73 (30%), Positives = 36/73 (49%), Gaps = 4/73 (5%)
Query: 104 NKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIED 163
+++V G ++ +C G P+P +W K G + PS + + E + L I VS ED
Sbjct: 255 SQMVLRGMDLLLECIASGVPTPDIAWYKKGGDL-PSDK---AKFENFNKALRITNVSEED 310
Query: 164 VGIYRITVENELG 176
G Y N++G
Sbjct: 311 SGEYFCLASNKMG 323
Score = 31.9 bits (69), Expect = 1.8
Identities = 21/85 (24%), Positives = 40/85 (47%), Gaps = 4/85 (4%)
Query: 106 VVEEGENVTFKCAVKGNPSPWASWDKDGSI--ITPSARITVKEKEEIMRI-LEIDEVSIE 162
+V+ +N+ +C KGNP+P W ++ I R++++ + + I E
Sbjct: 52 IVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEE 111
Query: 163 DVGIYRITVENELGRAEAS-ARLEV 186
G Y+ N+ G A ++ RL+V
Sbjct: 112 YEGEYQCFARNKFGTALSNRIRLQV 136
>AL391822-2|CAI14657.1| 619|Homo sapiens neurofascin homolog
(chicken) protein.
Length = 619
Score = 68.9 bits (161), Expect = 1e-11
Identities = 54/178 (30%), Positives = 82/178 (46%), Gaps = 20/178 (11%)
Query: 12 ECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLG 71
+C G+P P +RWF + Y++G+ L+IK + ED+G YTC A+N LG
Sbjct: 451 DCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGS--LEIKMIRKEDQGIYTCVATNILG 508
Query: 72 KAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS--PWASW 129
KA++ L V R+ Y P ++V G V +C VK +PS SW
Sbjct: 509 KAENQVRLEVKDPTRI-----------YRMPEDQVARRGTTVQLECRVKHDPSLKLTVSW 557
Query: 130 DKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVI 187
KD + R +K++++ + I + E D G Y EL + A A L V+
Sbjct: 558 LKDDEPLYIGNR--MKKEDDSLTIFGVAE---RDQGSYTCVASTELDQDLAKAYLTVL 610
Score = 59.7 bits (138), Expect = 8e-09
Identities = 44/176 (25%), Positives = 72/176 (40%), Gaps = 16/176 (9%)
Query: 12 ECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLG 71
EC +G P PDI W+ D ++ +++ L+I V+ ED G Y C ASN +G
Sbjct: 267 ECIASGVPTPDIAWYKKGG---DLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMG 323
Query: 72 KAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDK 131
+ + V + AP + P N ++ GE+ C GNP P W
Sbjct: 324 SIRHTISVRV-----------KAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMV 372
Query: 132 DGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVI 187
+G + + +E + + I +Y+ NE G A+A + V+
Sbjct: 373 NGEPLQSAP--PNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVL 426
Score = 50.4 bits (115), Expect = 5e-06
Identities = 48/188 (25%), Positives = 69/188 (36%), Gaps = 17/188 (9%)
Query: 1 MLSCDGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEG 60
++ G+ C+ GNP P ++W E ++ + G + +
Sbjct: 346 LILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDT-IIFRDTQISSRA 404
Query: 61 TYTCEASNCLGKAKSNACLVVYHT-RRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAV 119
Y C SN G +NA + V R+ SP Q+ +N+ C
Sbjct: 405 VYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVIL---YNR-------TRLDCPF 454
Query: 120 KGNPSPWASWDKDG-SIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRA 178
G+P P W K+G V E LEI + ED GIY N LG+A
Sbjct: 455 FGSPIPTLRWFKNGQGSNLDGGNYHVYENGS----LEIKMIRKEDQGIYTCVATNILGKA 510
Query: 179 EASARLEV 186
E RLEV
Sbjct: 511 ENQVRLEV 518
Score = 38.7 bits (86), Expect = 0.016
Identities = 37/128 (28%), Positives = 47/128 (36%), Gaps = 14/128 (10%)
Query: 7 DTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSY--DDGTARLKIKQ--VTAEDEGTY 62
D + EC+ GNP P W + D S GT + + E EG Y
Sbjct: 57 DNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEY 116
Query: 63 TCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKC-AVKG 121
C A N G A SN + L P + P VV+EG +T +C G
Sbjct: 117 QCFARNKFGTALSNRIRLQVSKSPL-WPKENLDPV--------VVQEGAPLTLQCNPPPG 167
Query: 122 NPSPWASW 129
PSP W
Sbjct: 168 LPSPVIFW 175
Score = 34.7 bits (76), Expect = 0.26
Identities = 22/73 (30%), Positives = 36/73 (49%), Gaps = 4/73 (5%)
Query: 104 NKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIED 163
+++V G ++ +C G P+P +W K G + PS + + E + L I VS ED
Sbjct: 255 SQMVLRGMDLLLECIASGVPTPDIAWYKKGGDL-PSDK---AKFENFNKALRITNVSEED 310
Query: 164 VGIYRITVENELG 176
G Y N++G
Sbjct: 311 SGEYFCLASNKMG 323
Score = 31.9 bits (69), Expect = 1.8
Identities = 21/85 (24%), Positives = 40/85 (47%), Gaps = 4/85 (4%)
Query: 106 VVEEGENVTFKCAVKGNPSPWASWDKDGSI--ITPSARITVKEKEEIMRI-LEIDEVSIE 162
+V+ +N+ +C KGNP+P W ++ I R++++ + + I E
Sbjct: 52 IVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEE 111
Query: 163 DVGIYRITVENELGRAEAS-ARLEV 186
G Y+ N+ G A ++ RL+V
Sbjct: 112 YEGEYQCFARNKFGTALSNRIRLQV 136
>AL117666-1|CAB56036.1| 483|Homo sapiens hypothetical protein
protein.
Length = 483
Score = 68.9 bits (161), Expect = 1e-11
Identities = 53/183 (28%), Positives = 75/183 (40%), Gaps = 19/183 (10%)
Query: 12 ECQVTGNPDPDIRWFHYAEVIRDCADFESSY---DDGTARLKIKQVTAEDEGTYTCEASN 68
EC TG+P+P I W A + DD I V +D G Y+C A N
Sbjct: 9 ECAATGHPNPQIAWQKDGGTDFPAARERRMHVMPDDDV--FFITDVKIDDAGVYSCTAQN 66
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G +NA L V T L P ++VV GE V +C GNP P +
Sbjct: 67 SAGSISANATLTVLETPSLVVPLE-----------DRVVSVGETVALQCKATGNPPPRIT 115
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVIT 188
W K ++ + R + + +L + V ED G Y + N LG A ++L V+
Sbjct: 116 WFKGDRPLSLTERHHLTPDNQ---LLVVQNVVAEDAGRYTCEMSNTLGTERAHSQLSVLP 172
Query: 189 RSG 191
+G
Sbjct: 173 AAG 175
Score = 54.8 bits (126), Expect = 2e-07
Identities = 29/76 (38%), Positives = 41/76 (53%), Gaps = 2/76 (2%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+TV +C+ TGNP P I WF + + D+ L ++ V AED G YTCE
Sbjct: 97 GETVALQCKATGNPPPRITWFKGDRPLSLTERHHLTPDNQL--LVVQNVVAEDAGRYTCE 154
Query: 66 ASNCLGKAKSNACLVV 81
SN LG ++++ L V
Sbjct: 155 MSNTLGTERAHSQLSV 170
>AJ306906-1|CAC37630.1| 2673|Homo sapiens fibulin-6 protein.
Length = 2673
Score = 68.9 bits (161), Expect = 1e-11
Identities = 59/180 (32%), Positives = 80/180 (44%), Gaps = 20/180 (11%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+ + C+ TG P P + W +I A F+S +G + L I++V+ ED GTY C
Sbjct: 1312 GEQLRLSCKATGIPLPKLTWTFNNNIIP--AHFDSV--NGHSELVIERVSKEDSGTYVCT 1367
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFY-TYPFNKVVEEGENVTFKCAVKGNPS 124
A N +G K A VY + P P F YP + + G N C VKG+P+
Sbjct: 1368 AENSVGFVK--AIGFVY----VKEP-----PVFKGDYPSHWIEPLGGNAILNCEVKGDPT 1416
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
P W++ G I S RI ++ L I ED G Y NE G E S L
Sbjct: 1417 PTIQWNRKGVDIEISHRI----RQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSL 1472
Score = 61.3 bits (142), Expect = 3e-09
Identities = 45/178 (25%), Positives = 73/178 (41%), Gaps = 12/178 (6%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
+ C+V+G P PD+ W + I+ + + G L+I + D G YTC A N
Sbjct: 20 ISLTCEVSGFPPPDLSWLKNEQPIK--LNTNTLIVPGGRTLQIIRAKVSDGGEYTCIAIN 77
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G++K L VY + + V EG +V+ + P P +
Sbjct: 78 QAGESKKKFSLTVYVPPSIKDHDSESLSVVN-------VREGTSVSLEXESNAVPPPVIT 130
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W K+G +IT S + + + +L I + + D G Y N GR + + L V
Sbjct: 131 WYKNGRMITESTHVEILADGQ---MLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNV 185
Score = 61.3 bits (142), Expect = 3e-09
Identities = 50/178 (28%), Positives = 64/178 (35%), Gaps = 10/178 (5%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
V C TG P P I W + I + E G ++L+I + D G YTC ASN
Sbjct: 207 VTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASN 266
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
GKA+ Y+ + P P + V GENV C G P+P
Sbjct: 267 MEGKAQK------YYFLSIQVPPSVAGAEI---PSDVSVLLGENVELVCNANGIPTPLIQ 317
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KDG I ++ L I D G Y N G + L V
Sbjct: 318 WLKDGKPIASGETERIRVSAN-GSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNV 374
Score = 60.1 bits (139), Expect = 6e-09
Identities = 48/168 (28%), Positives = 73/168 (43%), Gaps = 18/168 (10%)
Query: 13 CQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLGK 72
C G P P I W ++ + ++ G L ++ V ED G YTC A+N G+
Sbjct: 1228 CVADGIPTPAINWKKDNVLLANLLGKYTAEPYG--ELILENVVLEDSGFYTCVANNAAGE 1285
Query: 73 AKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKD 132
L V+ + PTF P + + +GE + C G P P +W +
Sbjct: 1286 DTHTVSLTVH-----------VLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFN 1334
Query: 133 GSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEA 180
+II P+ +V E++ I+ VS ED G Y T EN +G +A
Sbjct: 1335 NNII-PAHFDSVNGHSELV----IERVSKEDSGTYVCTAENSVGFVKA 1377
Score = 57.2 bits (132), Expect = 4e-08
Identities = 54/200 (27%), Positives = 74/200 (37%), Gaps = 29/200 (14%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSY---DDGTARLKIKQVTAEDEGTY 62
G C+V G+P P I+W R D E S+ G L I ED G Y
Sbjct: 1402 GGNAILNCEVKGDPTPTIQWN------RKGVDIEISHRIRQLGNGSLAIYGTVNEDAGDY 1455
Query: 63 TCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGN 122
TC A+N G + + L L SP P P V+ G + C G
Sbjct: 1456 TCVATNEAGVVERSMSLT------LQSP-----PIITLEPVETVINAGGKIILNCQATGE 1504
Query: 123 PSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASA 182
P P +W + G I+ R+ V L I + ED + N +G
Sbjct: 1505 PQPTITWSRQGHSISWDDRVNVLSNNS----LYIADAQKEDTSEFECVARNLMG--SVLV 1558
Query: 183 RLEVITRSGKFYGGLRAYSA 202
R+ VI + +GG +SA
Sbjct: 1559 RVPVIV---QVHGGFSQWSA 1575
Score = 56.8 bits (131), Expect = 6e-08
Identities = 49/174 (28%), Positives = 63/174 (36%), Gaps = 17/174 (9%)
Query: 13 CQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLGK 72
C+ TG P P I W + + G L+I + ED GTY C A N G
Sbjct: 1047 CEATGTPSPFITWQKEGINVNTSGRNHAVLPSGG--LQISRAVREDAGTYMCVAQNPAGT 1104
Query: 73 AKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKD 132
A L V Q+ P + V+ + +T C G P P +W KD
Sbjct: 1105 ALGKIKLNV-----------QVPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKD 1153
Query: 133 GSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
G I S R V L+I V D G Y N G + S +L V
Sbjct: 1154 GRAIVESIRQRVLSSGS----LQITFVQPGDAGHYTCMAANVAGSSSTSTKLTV 1203
Score = 56.8 bits (131), Expect = 6e-08
Identities = 48/178 (26%), Positives = 69/178 (38%), Gaps = 17/178 (9%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
+ C+ G P PDI W I + + G+ L+I V D G YTC A+N
Sbjct: 1134 ITLSCEADGLPPPDITWHKDGRAIVESIR-QRVLSSGS--LQITFVQPGDAGHYTCMAAN 1190
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G + ++ L V+ R+ S YT V E C G P+P +
Sbjct: 1191 VAGSSSTSTKLTVHVPPRIRS-----TEGHYT------VNENSQAILPCVADGIPTPAIN 1239
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KD ++ A + K E L ++ V +ED G Y N G + L V
Sbjct: 1240 WKKDNVLL---ANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHTVSLTV 1294
Score = 56.4 bits (130), Expect = 7e-08
Identities = 46/181 (25%), Positives = 70/181 (38%), Gaps = 11/181 (6%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+ VE C G P P I+W + I + L I D G YTC
Sbjct: 299 GENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCV 358
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A+N G+ L VY T + + A T +V+ N+ +C G P P
Sbjct: 359 ATNPAGEEDRIFNLNVYVTPTIRG-NKDEAEKLMT-----LVDTSINI--ECRATGTPPP 410
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
+W K+G + S+ I + +++RI+ + DV +Y N G L+
Sbjct: 411 QINWLKNGLPLPLSSHIRLLAAGQVIRIV---RAQVSDVAVYTCVASNRAGVDNKHYNLQ 467
Query: 186 V 186
V
Sbjct: 468 V 468
Score = 56.0 bits (129), Expect = 1e-07
Identities = 45/180 (25%), Positives = 72/180 (40%), Gaps = 14/180 (7%)
Query: 8 TVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEAS 67
++ EC+ TG P P I W + + R+ QV+ D YTC AS
Sbjct: 397 SINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVS--DVAVYTCVAS 454
Query: 68 NCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWA 127
N G + L V+ + + M T V +G + + C G P+P
Sbjct: 455 NRAGVDNKHYNLQVFAPPNMDN---SMGTEEIT------VLKGSSTSMACITDGTPAPSM 505
Query: 128 SWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVI 187
+W +DG + A +TV ++++L+ + ED G Y NE G L+V+
Sbjct: 506 AWLRDGQPLGLDAHLTVSTHGMVLQLLKAE---TEDSGKYTCIASNEAGEVSKHFILKVL 562
Score = 53.2 bits (122), Expect = 7e-07
Identities = 48/176 (27%), Positives = 68/176 (38%), Gaps = 15/176 (8%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G +V E + P P I W+ +I + E D L IK+ D G Y C
Sbjct: 111 EGTSVSLEXESNAVPPPVITWYKNGRMITESTHVEILADG--QMLHIKKAEVSDTGQYVC 168
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGEN-VTFKCAVKGNP 123
A N G+ N L VY + P R++ +VE N VT C G P
Sbjct: 169 RAINVAGRDDKNFHLNVYVPPSIEGPEREV-----------IVETISNPVTLTCDATGIP 217
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAE 179
P +W K+ I S + V+ + L+I D G Y N G+A+
Sbjct: 218 PPTIAWLKNHKRIENSDSLEVRILSGGSK-LQIARSQHSDSGNYTCIASNMEGKAQ 272
Score = 52.8 bits (121), Expect = 9e-07
Identities = 46/179 (25%), Positives = 67/179 (37%), Gaps = 18/179 (10%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
V EC+ P P I W E ++ A G L+I D YTC ASN
Sbjct: 677 VTLECKSDAVPPPVITWLRNGERLQ--ATPRVRILSGGRYLQINNADLGDTANYTCVASN 734
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
GK L V + P P + V+ ++ +C +G P+P +
Sbjct: 735 IAGKTTREFILTV-----------NVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRIT 783
Query: 129 WDKDGSIITPS-ARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W KDG+++ + AR ++ E L I + D G Y N G L+V
Sbjct: 784 WRKDGAVLAGNHARYSILEN----GFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQV 838
Score = 47.6 bits (108), Expect = 3e-05
Identities = 43/174 (24%), Positives = 57/174 (32%), Gaps = 16/174 (9%)
Query: 13 CQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLGK 72
C +G P P I W + D G + Q+ G YTC A N G
Sbjct: 956 CTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQLN--HAGRYTCVARNAAGS 1013
Query: 73 AKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKD 132
A + L V+ P P V + C G PSP+ +W K+
Sbjct: 1014 AHRHVTLHVHEP-----------PVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKE 1062
Query: 133 GSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
G + S R L+I ED G Y +N G A +L V
Sbjct: 1063 GINVNTSGR---NHAVLPSGGLQISRAVREDAGTYMCVAQNPAGTALGKIKLNV 1113
Score = 47.2 bits (107), Expect = 4e-05
Identities = 48/180 (26%), Positives = 67/180 (37%), Gaps = 24/180 (13%)
Query: 12 ECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLG 71
EC G P P I W V+ S ++G ++ VT D G Y C A+N G
Sbjct: 771 ECIAEGVPTPRITWRKDGAVLAGNHARYSILENGFLHIQSAHVT--DTGRYLCMATNAAG 828
Query: 72 KAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDK 131
+ L V H +PG P N V T C G P P +W K
Sbjct: 829 TDRRRIDLQV-HVPPSIAPG----------PTNMTVIVNVQTTLACEATGIPKPSINWRK 877
Query: 132 DGSIITPSARITVKEKEEIMRILE-----IDEVSIEDVGIYRITVENELGRAEASARLEV 186
+G + + V + + R+L I S++D Y TV N G + + L V
Sbjct: 878 NGHL------LNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGDDKRTVDLTV 931
Score = 46.8 bits (106), Expect = 6e-05
Identities = 38/171 (22%), Positives = 63/171 (36%), Gaps = 14/171 (8%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G + C G P P + W + + D + L++ + ED G YTC
Sbjct: 488 GSSTSMACITDGTPAPSMAWLRDGQPLG--LDAHLTVSTHGMVLQLLKAETEDSGKYTCI 545
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
ASN G+ + L V ++ + +V +T C G P+P
Sbjct: 546 ASNEAGEVSKHFILKVLEPPHINGSEEHEE-------ISVIVNNPLELT--CIASGIPAP 596
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG 176
+W KDG + + ++ E++R I +ED G Y + G
Sbjct: 597 KMTWMKDGRPLPQTDQVQTLGGGEVLR---ISTAQVEDTGRYTCLASSPAG 644
Score = 42.3 bits (95), Expect = 0.001
Identities = 41/176 (23%), Positives = 60/176 (34%), Gaps = 18/176 (10%)
Query: 13 CQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLGK 72
C+ TG P P I W ++ + S + L I + +D TY C +N G
Sbjct: 863 CEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGD 922
Query: 73 AKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKD 132
K L V Q+ P+ P + +V + C G P P W K+
Sbjct: 923 DKRTVDLTV-----------QVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKN 971
Query: 133 GSIITPSARITVKEKEEIMR--ILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
G + P + I+ +EI + G Y N G A L V
Sbjct: 972 GIRLLPRG-----DGYRILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHV 1022
Score = 40.7 bits (91), Expect = 0.004
Identities = 36/169 (21%), Positives = 61/169 (36%), Gaps = 14/169 (8%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASN 68
+E C +G P P + W + ++ G L+I ED G YTC AS+
Sbjct: 584 LELTCIASGIPAPKMTWMKDGRPLPQTDQVQTL--GGGEVLRISTAQVEDTGRYTCLASS 641
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G + V+ ++ P + V VT +C P P +
Sbjct: 642 PAGDDDKEYLVRVHVPPNIAGTDE---------PRDITVLRNRQVTLECKSDAVPPPVIT 692
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGR 177
W ++G + + R+ + R L+I+ + D Y N G+
Sbjct: 693 WLRNGERLQATPRVRILSGG---RYLQINNADLGDTANYTCVASNIAGK 738
>AF381545-1|AAK62357.1| 1093|Homo sapiens membrane glycoprotein
LRIG1 protein.
Length = 1093
Score = 68.9 bits (161), Expect = 1e-11
Identities = 53/183 (28%), Positives = 75/183 (40%), Gaps = 19/183 (10%)
Query: 12 ECQVTGNPDPDIRWFHYAEVIRDCADFESSY---DDGTARLKIKQVTAEDEGTYTCEASN 68
EC TG+P+P I W A + DD I V +D G Y+C A N
Sbjct: 619 ECAATGHPNPQIAWQKDGGTDFPAARERRMHVMPDDDV--FFITDVKIDDAGVYSCTAQN 676
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G +NA L V T L P ++VV GE V +C GNP P +
Sbjct: 677 SAGSISANATLTVLETPSLVVPLE-----------DRVVSVGETVALQCKATGNPPPRIT 725
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVIT 188
W K ++ + R + + +L + V ED G Y + N LG A ++L V+
Sbjct: 726 WFKGDRPLSLTERHHLTPDNQ---LLVVQNVVAEDAGRYTCEMSNTLGTERAHSQLSVLP 782
Query: 189 RSG 191
+G
Sbjct: 783 AAG 785
Score = 66.5 bits (155), Expect = 7e-11
Identities = 43/142 (30%), Positives = 63/142 (44%), Gaps = 10/142 (7%)
Query: 46 TARLKIKQVTAEDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNK 105
T L ++QVT EG Y C +N G S H RL+ + P+F P +
Sbjct: 559 TTILHLRQVTFGHEGRYQCVITNHFGSTYS-------HKARLTV---NVLPSFTKTPHDI 608
Query: 106 VVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVG 165
+ +CA G+P+P +W KDG P+AR + I +V I+D G
Sbjct: 609 TIRTTTVARLECAATGHPNPQIAWQKDGGTDFPAARERRMHVMPDDDVFFITDVKIDDAG 668
Query: 166 IYRITVENELGRAEASARLEVI 187
+Y T +N G A+A L V+
Sbjct: 669 VYSCTAQNSAGSISANATLTVL 690
Score = 54.8 bits (126), Expect = 2e-07
Identities = 29/76 (38%), Positives = 41/76 (53%), Gaps = 2/76 (2%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+TV +C+ TGNP P I WF + + D+ L ++ V AED G YTCE
Sbjct: 707 GETVALQCKATGNPPPRITWFKGDRPLSLTERHHLTPDNQL--LVVQNVVAEDAGRYTCE 764
Query: 66 ASNCLGKAKSNACLVV 81
SN LG ++++ L V
Sbjct: 765 MSNTLGTERAHSQLSV 780
>AC005338-1|AAC27825.1| 475|Homo sapiens PTPsigma, partial CDS
protein.
Length = 475
Score = 68.9 bits (161), Expect = 1e-11
Identities = 49/179 (27%), Positives = 74/179 (41%), Gaps = 14/179 (7%)
Query: 8 TVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEAS 67
T C +GNPDP+I WF + A + L+I+ D+G Y C A+
Sbjct: 25 TATMLCAASGNPDPEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEETDQGKYECVAT 84
Query: 68 NCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWA 127
N G S+ + RR+ AP F P + + G NV C G+P P+
Sbjct: 85 NSAGVRYSSPANLYVRVRRV-------APRFSILPMSHEIMPGGNVNITCVAVGSPMPYV 137
Query: 128 SWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
W + +TP + V +LE+ +V +D Y + LG EA A++ V
Sbjct: 138 KWMQGAEDLTPEDDMPVGR-----NVLELTDV--KDSANYTCVAMSSLGVIEAVAQITV 189
Score = 43.6 bits (98), Expect = 6e-04
Identities = 31/89 (34%), Positives = 38/89 (42%), Gaps = 2/89 (2%)
Query: 102 PFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSI 161
P KVVE T CA GNP P +W KD + PSA + K+ L+I+
Sbjct: 15 PQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDPSAS-NGRIKQLRSGALQIESSEE 73
Query: 162 EDVGIYRITVENELG-RAEASARLEVITR 189
D G Y N G R + A L V R
Sbjct: 74 TDQGKYECVATNSAGVRYSSPANLYVRVR 102
Score = 34.3 bits (75), Expect = 0.34
Identities = 21/76 (27%), Positives = 31/76 (40%), Gaps = 6/76 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G V C G+P P ++W AE D D R ++ +D YTC
Sbjct: 120 GGNVNITCVAVGSPMPYVKWMQGAE------DLTPEDDMPVGRNVLELTDVKDSANYTCV 173
Query: 66 ASNCLGKAKSNACLVV 81
A + LG ++ A + V
Sbjct: 174 AMSSLGVIEAVAQITV 189
>AB050468-1|BAB40659.1| 1094|Homo sapiens membrane glycoprotein
LIG-1 protein.
Length = 1094
Score = 68.9 bits (161), Expect = 1e-11
Identities = 53/183 (28%), Positives = 75/183 (40%), Gaps = 19/183 (10%)
Query: 12 ECQVTGNPDPDIRWFHYAEVIRDCADFESSY---DDGTARLKIKQVTAEDEGTYTCEASN 68
EC TG+P+P I W A + DD I V +D G Y+C A N
Sbjct: 619 ECAATGHPNPQIAWQKDGGTDFPAARERRMHVMPDDDV--FFITDVKIDDAGVYSCTAQN 676
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G +NA L V T L P ++VV GE V +C GNP P +
Sbjct: 677 SAGSISANATLTVLETPSLVVPLE-----------DRVVSVGETVALQCKATGNPPPRIT 725
Query: 129 WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVIT 188
W K ++ + R + + +L + V ED G Y + N LG A ++L V+
Sbjct: 726 WFKGDRPLSLTERHHLTPDNQ---LLVVQNVVAEDAGRYTCEMSNTLGTERAHSQLSVLP 782
Query: 189 RSG 191
+G
Sbjct: 783 AAG 785
Score = 66.9 bits (156), Expect = 5e-11
Identities = 43/142 (30%), Positives = 63/142 (44%), Gaps = 10/142 (7%)
Query: 46 TARLKIKQVTAEDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNK 105
T L ++QVT EG Y C +N G S H RL+ + P+F P +
Sbjct: 559 TTILHLRQVTFGHEGRYQCVITNHFGSTYS-------HKARLTV---NVLPSFTKTPHDI 608
Query: 106 VVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVG 165
+ +CA G+P+P +W KDG P+AR + I +V I+D G
Sbjct: 609 TIRTTTMARLECAATGHPNPQIAWQKDGGTDFPAARERRMHVMPDDDVFFITDVKIDDAG 668
Query: 166 IYRITVENELGRAEASARLEVI 187
+Y T +N G A+A L V+
Sbjct: 669 VYSCTAQNSAGSISANATLTVL 690
Score = 54.8 bits (126), Expect = 2e-07
Identities = 29/76 (38%), Positives = 41/76 (53%), Gaps = 2/76 (2%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+TV +C+ TGNP P I WF + + D+ L ++ V AED G YTCE
Sbjct: 707 GETVALQCKATGNPPPRITWFKGDRPLSLTERHHLTPDNQL--LVVQNVVAEDAGRYTCE 764
Query: 66 ASNCLGKAKSNACLVV 81
SN LG ++++ L V
Sbjct: 765 MSNTLGTERAHSQLSV 780
>M63888-1|AAA35959.1| 662|Homo sapiens heparin-binding growth
factor receptor protein.
Length = 662
Score = 68.5 bits (160), Expect = 2e-11
Identities = 59/195 (30%), Positives = 82/195 (42%), Gaps = 23/195 (11%)
Query: 8 TVEFECQVTGNPDPDIRWFHYAEVIRD---CADFESSYDDGTARLKIKQVTAEDEGTYTC 64
TV+F+C +G P+P +RW + + ++ Y T + + V D+G YTC
Sbjct: 173 TVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRY--ATWSIIMDSVVPSDKGNYTC 230
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
N G L V SP R + P NK V G NV F C V +P
Sbjct: 231 IVENEYGSINHTYQLDVVER----SPHRPILQA--GLPANKTVALGSNVEFMCKVYSDPQ 284
Query: 125 PWASWDK----DGSIITPS----ARIT----VKEKEEIMRILEIDEVSIEDVGIYRITVE 172
P W K +GS I P A+I V ++ M +L + VS ED G Y
Sbjct: 285 PHIQWLKHIEVNGSKIGPDNLPYAQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAG 344
Query: 173 NELGRAEASARLEVI 187
N +G + SA L V+
Sbjct: 345 NSIGLSHHSAWLTVL 359
Score = 48.8 bits (111), Expect = 1e-05
Identities = 32/108 (29%), Positives = 45/108 (41%), Gaps = 5/108 (4%)
Query: 88 SSPGRQMAPTFYTYPFNK-----VVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARI 142
+ P R ++T P V + V FKC G P+P W K+G P RI
Sbjct: 144 TKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRI 203
Query: 143 TVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVITRS 190
+ + +D V D G Y VENE G + +L+V+ RS
Sbjct: 204 GGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERS 251
Score = 41.1 bits (92), Expect = 0.003
Identities = 29/90 (32%), Positives = 41/90 (45%), Gaps = 15/90 (16%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEV--------------IRDCADFESSYDDGTARLKI 51
G VEF C+V +P P I+W + EV I A ++ D L +
Sbjct: 270 GSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYAQILKTAGVNTT-DKEMEVLHL 328
Query: 52 KQVTAEDEGTYTCEASNCLGKAKSNACLVV 81
+ V+ ED G YTC A N +G + +A L V
Sbjct: 329 RNVSFEDAGEYTCLAGNSIGLSHHSAWLTV 358
>M63887-1|AAA35958.1| 822|Homo sapiens heparin-binding growth
factor receptor protein.
Length = 822
Score = 68.5 bits (160), Expect = 2e-11
Identities = 59/195 (30%), Positives = 82/195 (42%), Gaps = 23/195 (11%)
Query: 8 TVEFECQVTGNPDPDIRWFHYAEVIRD---CADFESSYDDGTARLKIKQVTAEDEGTYTC 64
TV+F+C +G P+P +RW + + ++ Y T + + V D+G YTC
Sbjct: 173 TVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRY--ATWSIIMDSVVPSDKGNYTC 230
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
N G L V SP R + P NK V G NV F C V +P
Sbjct: 231 IVENEYGSINHTYQLDVVER----SPHRPILQA--GLPANKTVALGSNVEFMCKVYSDPQ 284
Query: 125 PWASWDK----DGSIITPS----ARIT----VKEKEEIMRILEIDEVSIEDVGIYRITVE 172
P W K +GS I P A+I V ++ M +L + VS ED G Y
Sbjct: 285 PHIQWLKHIEVNGSKIGPDNLPYAQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAG 344
Query: 173 NELGRAEASARLEVI 187
N +G + SA L V+
Sbjct: 345 NSIGLSHHSAWLTVL 359
Score = 48.8 bits (111), Expect = 1e-05
Identities = 32/108 (29%), Positives = 45/108 (41%), Gaps = 5/108 (4%)
Query: 88 SSPGRQMAPTFYTYPFNK-----VVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARI 142
+ P R ++T P V + V FKC G P+P W K+G P RI
Sbjct: 144 TKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRI 203
Query: 143 TVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVITRS 190
+ + +D V D G Y VENE G + +L+V+ RS
Sbjct: 204 GGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERS 251
Score = 41.1 bits (92), Expect = 0.003
Identities = 29/90 (32%), Positives = 41/90 (45%), Gaps = 15/90 (16%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEV--------------IRDCADFESSYDDGTARLKI 51
G VEF C+V +P P I+W + EV I A ++ D L +
Sbjct: 270 GSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYAQILKTAGVNTT-DKEMEVLHL 328
Query: 52 KQVTAEDEGTYTCEASNCLGKAKSNACLVV 81
+ V+ ED G YTC A N +G + +A L V
Sbjct: 329 RNVSFEDAGEYTCLAGNSIGLSHHSAWLTV 358
>M34641-1|AAA35835.1| 820|Homo sapiens protein ( Human fibroblast
growth factor (FGF) receptor-1 mRNA, complete cds. ).
Length = 820
Score = 68.5 bits (160), Expect = 2e-11
Identities = 59/197 (29%), Positives = 83/197 (42%), Gaps = 27/197 (13%)
Query: 8 TVEFECQVTGNPDPDIRWFHYAEVIRD---CADFESSYDDGTARLKIKQVTAEDEGTYTC 64
TV+F+C +G P+P +RW ++ + ++ Y T + + V D+G YTC
Sbjct: 171 TVKFKCPSSGTPNPTLRWLKNSKEFKPDHRIGGYKVRY--ATWSIIMDSVVPSDKGNYTC 228
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
N G L V SP R + P NK V G NV F C V +P
Sbjct: 229 IVENEYGSINHTYQLDVVER----SPHRPILQA--GLPANKTVALGSNVEFMCKVYSDPQ 282
Query: 125 PWASWDK----DGSIITP----------SARITVKEKEEIMRILEIDEVSIEDVGIYRIT 170
P W K +GS I P +A + +KE M +L + VS ED G Y
Sbjct: 283 PHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKE--MEVLHLRNVSFEDAGEYTCL 340
Query: 171 VENELGRAEASARLEVI 187
N +G + SA L V+
Sbjct: 341 AGNSIGLSHHSAWLTVL 357
Score = 46.0 bits (104), Expect = 1e-04
Identities = 27/84 (32%), Positives = 37/84 (44%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
V + V FKC G P+P W K+ P RI + + +D V D G
Sbjct: 166 VPAAKTVKFKCPSSGTPNPTLRWLKNSKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGN 225
Query: 167 YRITVENELGRAEASARLEVITRS 190
Y VENE G + +L+V+ RS
Sbjct: 226 YTCIVENEYGSINHTYQLDVVERS 249
Score = 41.1 bits (92), Expect = 0.003
Identities = 29/90 (32%), Positives = 41/90 (45%), Gaps = 15/90 (16%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEV--------------IRDCADFESSYDDGTARLKI 51
G VEF C+V +P P I+W + EV I A ++ D L +
Sbjct: 268 GSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTT-DKEMEVLHL 326
Query: 52 KQVTAEDEGTYTCEASNCLGKAKSNACLVV 81
+ V+ ED G YTC A N +G + +A L V
Sbjct: 327 RNVSFEDAGEYTCLAGNSIGLSHHSAWLTV 356
>M34186-1|AAA35837.1| 731|Homo sapiens protein ( Human fibroblast
growth factor receptor (FGFr) transmembrane form mRNA,
complete cds. ).
Length = 731
Score = 68.5 bits (160), Expect = 2e-11
Identities = 59/197 (29%), Positives = 82/197 (41%), Gaps = 27/197 (13%)
Query: 8 TVEFECQVTGNPDPDIRWFHYAEVIRD---CADFESSYDDGTARLKIKQVTAEDEGTYTC 64
TV+F+C +G P+P +RW + + ++ Y T + + V D+G YTC
Sbjct: 82 TVKFKCPSSGTPNPTLRWLENGKEFKPDHRIGGYKVRY--ATWSIIMDSVVPSDKGNYTC 139
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
N G L V SP R + P NK V G NV F C V +P
Sbjct: 140 IVENEYGSINHTYQLDVVER----SPHRPILQA--GLPANKTVALGSNVEFMCKVYSDPQ 193
Query: 125 PWASWDK----DGSIITP----------SARITVKEKEEIMRILEIDEVSIEDVGIYRIT 170
P W K +GS I P +A + +KE M +L + VS ED G Y
Sbjct: 194 PHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKE--MEVLHLRNVSFEDAGEYTCL 251
Query: 171 VENELGRAEASARLEVI 187
N +G + SA L V+
Sbjct: 252 AGNSIGLSHHSAWLTVL 268
Score = 46.8 bits (106), Expect = 6e-05
Identities = 27/84 (32%), Positives = 38/84 (45%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
V + V FKC G P+P W ++G P RI + + +D V D G
Sbjct: 77 VPAAKTVKFKCPSSGTPNPTLRWLENGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGN 136
Query: 167 YRITVENELGRAEASARLEVITRS 190
Y VENE G + +L+V+ RS
Sbjct: 137 YTCIVENEYGSINHTYQLDVVERS 160
Score = 41.1 bits (92), Expect = 0.003
Identities = 29/90 (32%), Positives = 41/90 (45%), Gaps = 15/90 (16%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEV--------------IRDCADFESSYDDGTARLKI 51
G VEF C+V +P P I+W + EV I A ++ D L +
Sbjct: 179 GSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTT-DKEMEVLHL 237
Query: 52 KQVTAEDEGTYTCEASNCLGKAKSNACLVV 81
+ V+ ED G YTC A N +G + +A L V
Sbjct: 238 RNVSFEDAGEYTCLAGNSIGLSHHSAWLTV 267
>AF058332-2|AAD22604.1| 926|Homo sapiens myocardium-specific titin
protein.
Length = 926
Score = 68.5 bits (160), Expect = 2e-11
Identities = 53/196 (27%), Positives = 76/196 (38%), Gaps = 14/196 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
GD V G P P I+WF ++ AD++ +D L I EDEG YTC
Sbjct: 63 GDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCM 122
Query: 66 ASNCLGKAKSNACLVVYH--------------TRRLSSPGRQMAPTFYTYPFNKVVEEGE 111
ASN GK +A L + + L G P F +G
Sbjct: 123 ASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGL 182
Query: 112 NVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITV 171
F+ V G P+P +W K+ + S T+ +++ ED G+Y
Sbjct: 183 PAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKA 242
Query: 172 ENELGRAEASARLEVI 187
EN LG + +A L V+
Sbjct: 243 ENMLGESTCAAELLVL 258
Score = 41.5 bits (93), Expect = 0.002
Identities = 38/138 (27%), Positives = 59/138 (42%), Gaps = 10/138 (7%)
Query: 54 VTAEDEGTYTCEASNCLGKAKSNACLV----VYHTRRLSSPGRQMAPTFYTYPFNKVVEE 109
++AE+EG ++ E L K L+ VY T+ S P F N +
Sbjct: 6 LSAEEEGLHSAELQ--LSKINETLELLSESPVYPTK-FDSEKEGTGPIFIKEVSNADISM 62
Query: 110 GENVTFKCAVKGNPSPWASWDKDGSIITPSARIT-VKEKEEIMRILEIDEVSIEDVGIYR 168
G+ T V G P P W +G ++TPSA V + ++ I+ +ED G Y
Sbjct: 63 GDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILF--TKLEDEGEYT 120
Query: 169 ITVENELGRAEASARLEV 186
N+ G+ SA L++
Sbjct: 121 CMASNDYGKTICSAYLKI 138
Score = 41.5 bits (93), Expect = 0.002
Identities = 25/81 (30%), Positives = 39/81 (48%), Gaps = 3/81 (3%)
Query: 2 LSCDGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAED-EG 60
+S +GD V +T + + W+ +++ F+ D T L I +V ED +G
Sbjct: 845 VSEEGDIVHLTTSITNAKE--VNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQG 902
Query: 61 TYTCEASNCLGKAKSNACLVV 81
Y CEA N GK ++A L V
Sbjct: 903 EYVCEALNDSGKTATSAKLTV 923
>AF058332-1|AAD22603.1| 1019|Homo sapiens titin protein.
Length = 1019
Score = 68.5 bits (160), Expect = 2e-11
Identities = 53/196 (27%), Positives = 76/196 (38%), Gaps = 14/196 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
GD V G P P I+WF ++ AD++ +D L I EDEG YTC
Sbjct: 63 GDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCM 122
Query: 66 ASNCLGKAKSNACLVVYH--------------TRRLSSPGRQMAPTFYTYPFNKVVEEGE 111
ASN GK +A L + + L G P F +G
Sbjct: 123 ASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGL 182
Query: 112 NVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITV 171
F+ V G P+P +W K+ + S T+ +++ ED G+Y
Sbjct: 183 PAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKA 242
Query: 172 ENELGRAEASARLEVI 187
EN LG + +A L V+
Sbjct: 243 ENMLGESTCAAELLVL 258
Score = 60.5 bits (140), Expect = 5e-09
Identities = 50/186 (26%), Positives = 76/186 (40%), Gaps = 13/186 (6%)
Query: 2 LSCDGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAED-EG 60
+S +GD V +T + + W+ +++ F+ D T L I +V ED +G
Sbjct: 845 VSEEGDIVHLTTSITNAKE--VNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQG 902
Query: 61 TYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVK 120
Y CEA N GK ++A L V ++ AP V G F C ++
Sbjct: 903 EYVCEALNDSGKTATSAKLTVV---------KRAAPVIKRKIEPLEVALGHLAKFTCEIQ 953
Query: 121 GNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEA 180
P+ W K G I S + +++ + I LEI + D G Y NE G
Sbjct: 954 SAPNVRFQWFKAGREIYESDKCSIRSSKYISS-LEILRTQVVDCGEYTCKASNEYGSVSC 1012
Query: 181 SARLEV 186
+A L V
Sbjct: 1013 TATLTV 1018
Score = 41.5 bits (93), Expect = 0.002
Identities = 38/138 (27%), Positives = 59/138 (42%), Gaps = 10/138 (7%)
Query: 54 VTAEDEGTYTCEASNCLGKAKSNACLV----VYHTRRLSSPGRQMAPTFYTYPFNKVVEE 109
++AE+EG ++ E L K L+ VY T+ S P F N +
Sbjct: 6 LSAEEEGLHSAELQ--LSKINETLELLSESPVYPTK-FDSEKEGTGPIFIKEVSNADISM 62
Query: 110 GENVTFKCAVKGNPSPWASWDKDGSIITPSARIT-VKEKEEIMRILEIDEVSIEDVGIYR 168
G+ T V G P P W +G ++TPSA V + ++ I+ +ED G Y
Sbjct: 63 GDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILF--TKLEDEGEYT 120
Query: 169 ITVENELGRAEASARLEV 186
N+ G+ SA L++
Sbjct: 121 CMASNDYGKTICSAYLKI 138
>X66945-1|CAA47375.1| 822|Homo sapiens fibroblast growth factor
receptor protein.
Length = 822
Score = 68.1 bits (159), Expect = 2e-11
Identities = 59/197 (29%), Positives = 82/197 (41%), Gaps = 27/197 (13%)
Query: 8 TVEFECQVTGNPDPDIRWFHYAEVIRD---CADFESSYDDGTARLKIKQVTAEDEGTYTC 64
TV+F+C +G P+P +RW + + ++ Y T + + V D+G YTC
Sbjct: 173 TVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRY--ATWSIIMDSVVPSDKGNYTC 230
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
N G L V SP R + P NK V G NV F C V +P
Sbjct: 231 IVENEYGSINHTYQLDVVER----SPHRPILQA--GLPANKTVALGSNVEFMCKVYSDPQ 284
Query: 125 PWASWDK----DGSIITP----------SARITVKEKEEIMRILEIDEVSIEDVGIYRIT 170
P W K +GS I P +A + +KE M +L + VS ED G Y
Sbjct: 285 PHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKE--MEVLHLRNVSFEDAGEYTCL 342
Query: 171 VENELGRAEASARLEVI 187
N +G + SA L V+
Sbjct: 343 AGNSIGLSHHSAWLTVL 359
Score = 48.8 bits (111), Expect = 1e-05
Identities = 32/108 (29%), Positives = 45/108 (41%), Gaps = 5/108 (4%)
Query: 88 SSPGRQMAPTFYTYPFNK-----VVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARI 142
+ P R ++T P V + V FKC G P+P W K+G P RI
Sbjct: 144 TKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRI 203
Query: 143 TVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVITRS 190
+ + +D V D G Y VENE G + +L+V+ RS
Sbjct: 204 GGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERS 251
Score = 41.1 bits (92), Expect = 0.003
Identities = 29/90 (32%), Positives = 41/90 (45%), Gaps = 15/90 (16%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEV--------------IRDCADFESSYDDGTARLKI 51
G VEF C+V +P P I+W + EV I A ++ D L +
Sbjct: 270 GSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTT-DKEMEVLHL 328
Query: 52 KQVTAEDEGTYTCEASNCLGKAKSNACLVV 81
+ V+ ED G YTC A N +G + +A L V
Sbjct: 329 RNVSFEDAGEYTCLAGNSIGLSHHSAWLTV 358
>X62515-1|CAA44373.1| 4393|Homo sapiens Human basement membrane
heparan sulfate proteoglycan core protein protein.
Length = 4393
Score = 68.1 bits (159), Expect = 2e-11
Identities = 55/185 (29%), Positives = 76/185 (41%), Gaps = 27/185 (14%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G VEFEC G+P P + W +R G ++I V D G Y C
Sbjct: 3505 GHAVEFECLALGDPKPQVTWSKVGGHLRP-----GIVQSGGV-VRIAHVELADAGQYRCT 3558
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A+N G +S+ L+V ++S P P G F C G P+P
Sbjct: 3559 ATNAAGTTQSHVLLLVQALPQISMPQEVRVPA------------GSAAVFPCIASGYPTP 3606
Query: 126 WASWDK-DGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
SW K DGS + P +R+ E +M + V +D G Y T N G+ +A A L
Sbjct: 3607 DISWSKLDGS-LPPDSRL---ENNMLM----LPSVQPQDAGTYVCTATNRQGKVKAFAHL 3658
Query: 185 EVITR 189
+V R
Sbjct: 3659 QVPER 3663
Score = 64.5 bits (150), Expect = 3e-10
Identities = 53/181 (29%), Positives = 80/181 (44%), Gaps = 24/181 (13%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G T C TG+P I W +R ++ + T L I +V +D G Y C
Sbjct: 3228 GHTATLRCSATGSPARTIHW----SKLRSPLPWQHRLEGDT--LIIPRVAQQDSGQYICN 3281
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A++ G A++ ++ H + SP P T P + V+ GE V +C G P
Sbjct: 3282 ATSPAGHAEAT---IILH---VESP-----PYATTVPEHASVQAGETVQLQCLAHGTPPL 3330
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
W + GS + R T + + +L + + ED G YR V N++G AEA A+L
Sbjct: 3331 TFQWSRVGSSLP--GRATARNE-----LLHFERAAPEDSGRYRCRVTNKVGSAEAFAQLL 3383
Query: 186 V 186
V
Sbjct: 3384 V 3384
Score = 62.9 bits (146), Expect = 8e-10
Identities = 52/199 (26%), Positives = 80/199 (40%), Gaps = 18/199 (9%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G EF C TG+P P + W ++ G RL + T D+ Y C
Sbjct: 1882 GQLAEFRCSATGSPTPTLEW---TGGPGGQLPAKAQIHGGILRLPAVEPT--DQAQYLCR 1936
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A + G+ + A V H P Q++P V G V C G PS
Sbjct: 1937 AHSSAGQQVARA---VLHVHGGGGPRVQVSPE------RTQVHAGRTVRLYCRAAGVPSA 1987
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
+W K+G + P AR E+ +I +L I ++ D G Y + G A+A ++
Sbjct: 1988 TITWRKEGGSLPPQAR---SERTDIATLL-IPAITTADAGFYLCVATSPAGTAQARIQVV 2043
Query: 186 VITRSGKFYGGLRAYSASP 204
V++ S ++ S+SP
Sbjct: 2044 VLSASDASQPPVKIESSSP 2062
Score = 61.7 bits (143), Expect = 2e-09
Identities = 51/181 (28%), Positives = 80/181 (44%), Gaps = 22/181 (12%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G +VEF C V + +RWF + S DG L+I+ + +GTY C+
Sbjct: 3416 GASVEFHCAVPSDRGTQLRWFKEGGQLPP----GHSVQDGV--LRIQNLDQSCQGTYICQ 3469
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A GKA+++A LV+ + L S + + T V G V F+C G+P P
Sbjct: 3470 AHGPWGKAQASAQLVI---QALPSVLINIRTSVQT------VVVGHAVEFECLALGDPKP 3520
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
+W K G + P + + ++RI ++ + D G YR T N G ++ L
Sbjct: 3521 QVTWSKVGGHLRPG----IVQSGGVVRIAHVE---LADAGQYRCTATNAAGTTQSHVLLL 3573
Query: 186 V 186
V
Sbjct: 3574 V 3574
Score = 58.8 bits (136), Expect = 1e-08
Identities = 49/181 (27%), Positives = 68/181 (37%), Gaps = 12/181 (6%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G V EC G P RW + D L+I D GTY C
Sbjct: 3129 GKAVTLECVSAGEPRSSARWTRISSTPAKLEQRTYGLMDSHTVLQISSAKPSDAGTYVCL 3188
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A N LG A+ ++V +PG AP VE G T +C+ G+P+
Sbjct: 3189 AQNALGTAQKQVEVIV--DTGAMAPG---APQVQAEEAELTVEAGHTATLRCSATGSPAR 3243
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
W K S + R+ E + ++ I V+ +D G Y + G AEA+ L
Sbjct: 3244 TIHWSKLRSPLPWQHRL---EGDTLI----IPRVAQQDSGQYICNATSPAGHAEATIILH 3296
Query: 186 V 186
V
Sbjct: 3297 V 3297
Score = 56.0 bits (129), Expect = 1e-07
Identities = 48/187 (25%), Positives = 74/187 (39%), Gaps = 15/187 (8%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G T++ C V I W+ S + +RL+I QVT D G Y C
Sbjct: 2549 NGHTLDLNCLVASQAPHTITWYKRG------GSLPSRHQIVGSRLRIPQVTPADSGEYVC 2602
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
SN G +++ L+V SS +++P + V EG+ + C V P
Sbjct: 2603 HVSNGAGSRETS--LIVTIQGSGSSHVPRVSPPIRIESSSPTVVEGQTLDLNCVVARQPQ 2660
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
+W K G + PS T L + ++S+ D G Y N + EAS +
Sbjct: 2661 AIITWYKRGGSL-PSRHQTHGSH------LRLHQMSVADSGEYVCRANNNIDALEASIVI 2713
Query: 185 EVITRSG 191
V +G
Sbjct: 2714 SVSPSAG 2720
Score = 55.6 bits (128), Expect = 1e-07
Identities = 46/184 (25%), Positives = 78/184 (42%), Gaps = 16/184 (8%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+TV+ +C G P +W + A + L ++ ED G Y C
Sbjct: 3315 GETVQLQCLAHGTPPLTFQWSRVGSSLPGRATARNEL------LHFERAAPEDSGRYRCR 3368
Query: 66 ASNCLGKAKSNACLVVYH---TRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGN 122
+N +G A++ A L+V + +S PT P + G +V F CAV +
Sbjct: 3369 VTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQVTPQLETKSIGASVEFHCAVPSD 3428
Query: 123 PSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASA 182
W K+G + P + ++ ++RI +D+ S + G Y G+A+ASA
Sbjct: 3429 RGTQLRWFKEGGQLPPGHSV----QDGVLRIQNLDQ-SCQ--GTYICQAHGPWGKAQASA 3481
Query: 183 RLEV 186
+L +
Sbjct: 3482 QLVI 3485
Score = 54.0 bits (124), Expect = 4e-07
Identities = 51/191 (26%), Positives = 76/191 (39%), Gaps = 18/191 (9%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G TV C+ G P I W + A E + A L I +T D G Y C
Sbjct: 1972 GRTVRLYCRAAGVPSATITWRKEGGSLPPQARSERT---DIATLLIPAITTADAGFYLCV 2028
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A++ G A++ +VV S P ++ + + V EG+ + C V G+
Sbjct: 2029 ATSPAGTAQARIQVVVLSASDASQPPVKIESS------SPSVTEGQTLDLNCVVAGSAHA 2082
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
+W + G + ++ L + +VS D G Y VEN G EAS +
Sbjct: 2083 QVTWYRRGGSLPHHTQVHGSR-------LRLPQVSPADSGEYVCRVENGSGPKEASITVS 2135
Query: 186 VI--TRSGKFY 194
V+ T SG Y
Sbjct: 2136 VLHGTHSGPSY 2146
Score = 54.0 bits (124), Expect = 4e-07
Identities = 43/184 (23%), Positives = 71/184 (38%), Gaps = 15/184 (8%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G+T++ C V G + W S + +RL++ V+ D G Y C
Sbjct: 2742 EGETLDLNCVVPGQAHAQVTWHKRG------GSLPSYHQTRGSRLRLHHVSPADSGEYVC 2795
Query: 65 EASNCLGKAKSNACLVVYHT--RRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGN 122
G +++ + + + + P AP P + V EG+ + KC V G
Sbjct: 2796 RVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPIRIEPSSSRVAEGQTLDLKCVVPGQ 2855
Query: 123 PSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASA 182
+W K G + AR V +L +++VS D G Y V G EAS
Sbjct: 2856 AHAQVTWHKRGGNL--PARHQVHGP-----LLRLNQVSPADSGEYSCQVTGSSGTLEASV 2908
Query: 183 RLEV 186
+ +
Sbjct: 2909 LVTI 2912
Score = 51.6 bits (118), Expect = 2e-06
Identities = 49/188 (26%), Positives = 74/188 (39%), Gaps = 17/188 (9%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G T++ C V P I W+ S + + L++ Q++ D G Y C
Sbjct: 2645 EGQTLDLNCVVARQPQAIITWYKRG------GSLPSRHQTHGSHLRLHQMSVADSGEYVC 2698
Query: 65 EASNCLGKAKSNACLVVYHTRRL-SSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
A+N + +++ + V + S+PG M + + V EGE + C V G
Sbjct: 2699 RANNNIDALEASIVISVSPSAGSPSAPGSSMPIRIESSSSH--VAEGETLDLNCVVPGQA 2756
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
+W K G + PS T + L + VS D G Y V G EAS
Sbjct: 2757 HAQVTWHKRGGSL-PSYHQTRGSR------LRLHHVSPADSGEYVCRVMGSSGPLEASV- 2808
Query: 184 LEVITRSG 191
L I SG
Sbjct: 2809 LVTIEASG 2816
Score = 50.8 bits (116), Expect = 4e-06
Identities = 44/186 (23%), Positives = 70/186 (37%), Gaps = 18/186 (9%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G T++ C V G+ + W+ + S RL++ QV+ D G Y C
Sbjct: 2066 EGQTLDLNCVVAGSAHAQVTWYRRGGSLPHHTQVHGS------RLRLPQVSPADSGEYVC 2119
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAP----TFYTYPFNKVVEEGENVTFKCAVK 120
N G +++ + V H S P P P + V EG+ + C V
Sbjct: 2120 RVENGSGPKEASITVSVLHGTH-SGPSYTPVPGSTRPIRIEPSSSHVAEGQTLDLNCVVP 2178
Query: 121 GNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEA 180
G +W K G + P+ T +L + +V+ D G Y V G EA
Sbjct: 2179 GQAHAQVTWHKRGGSL-PARHQTHGS------LLRLHQVTPADSGEYVCHVVGTSGPLEA 2231
Query: 181 SARLEV 186
S + +
Sbjct: 2232 SVLVTI 2237
Score = 46.8 bits (106), Expect = 6e-05
Identities = 38/183 (20%), Positives = 70/183 (38%), Gaps = 13/183 (7%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G T++ C V G + W+ + + ++L++ V+ D G Y C
Sbjct: 2940 EGQTLDLNCVVPGQAHAQVTWYKRG------GSLPARHQTHGSQLRLHHVSPADSGEYVC 2993
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
A+ G + + V SS R +P P + V++G++ +FKC + +
Sbjct: 2994 RAAGGPGPEQEASFTVTVPPSEGSSY-RLRSPVISIDPPSSTVQQGQDASFKCLIHDGAA 3052
Query: 125 PWA-SWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
P + W + + I+ I+ I + G YR N G A++
Sbjct: 3053 PISLEWKTRNQELEDNVHISPNGS-----IITIVGTRPSNHGTYRCVASNAYGVAQSVVN 3107
Query: 184 LEV 186
L V
Sbjct: 3108 LSV 3110
Score = 46.4 bits (105), Expect = 8e-05
Identities = 26/81 (32%), Positives = 36/81 (44%), Gaps = 6/81 (7%)
Query: 49 LKIKQVTAEDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVE 108
L I+ V D GTY C SN + A L V + LS AP +P V+
Sbjct: 1827 LTIRNVQLSDAGTYVCTGSNMFAMDQGTATLHVQASGTLS------APVVSIHPPQLTVQ 1880
Query: 109 EGENVTFKCAVKGNPSPWASW 129
G+ F+C+ G+P+P W
Sbjct: 1881 PGQLAEFRCSATGSPTPTLEW 1901
Score = 46.0 bits (104), Expect = 1e-04
Identities = 26/129 (20%), Positives = 51/129 (39%), Gaps = 6/129 (4%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G T++ +C V G + W + + + L++ QV+ D G Y+C
Sbjct: 2842 EGQTLDLKCVVPGQAHAQVTWHKRG------GNLPARHQVHGPLLRLNQVSPADSGEYSC 2895
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
+ + G +++ + + + P +A Y + V EG+ + C V G
Sbjct: 2896 QVTGSSGTLEASVLVTIEPSSPGPIPAPGLAQPIYIEASSSHVTEGQTLDLNCVVPGQAH 2955
Query: 125 PWASWDKDG 133
+W K G
Sbjct: 2956 AQVTWYKRG 2964
Score = 45.2 bits (102), Expect = 2e-04
Identities = 31/129 (24%), Positives = 48/129 (37%), Gaps = 8/129 (6%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G T++ C V G + W+ + + +RL I Q + D G Y C
Sbjct: 2260 EGQTLDLSCVVAGQAHAQVTWYKRG------GSLPARHQVRGSRLYIFQASPADAGQYVC 2313
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
ASN + +A + L+ P P P + V EG+ + C V G
Sbjct: 2314 RASNGM-EASITVTVTGTQGANLAYPAGSTQP-IRIEPSSSQVAEGQTLDLNCVVPGQSH 2371
Query: 125 PWASWDKDG 133
+W K G
Sbjct: 2372 AQVTWHKRG 2380
Score = 44.4 bits (100), Expect = 3e-04
Identities = 42/140 (30%), Positives = 58/140 (41%), Gaps = 15/140 (10%)
Query: 58 DEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKV-VEEGENVTFK 116
+ GTY C ASN G A+S L V+ P PT P V V+ G+ VT +
Sbjct: 3087 NHGTYRCVASNAYGVAQSVVNLSVH------GP-----PTVSVLPEGPVWVKVGKAVTLE 3135
Query: 117 CAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG 176
C G P A W + S + T + +L+I D G Y +N LG
Sbjct: 3136 CVSAGEPRSSARWTRISSTPAKLEQRTYGLMDS-HTVLQISSAKPSDAGTYVCLAQNALG 3194
Query: 177 RAEASARLEVITRSGKFYGG 196
A+ ++EVI +G G
Sbjct: 3195 TAQ--KQVEVIVDTGAMAPG 3212
Score = 39.9 bits (89), Expect = 0.007
Identities = 45/194 (23%), Positives = 69/194 (35%), Gaps = 16/194 (8%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G T++ C V G + W + + L++ Q + D G Y C
Sbjct: 2356 EGQTLDLNCVVPGQSHAQVTWHKRG------GSLPVRHQTHGSLLRLYQASPADSGEYVC 2409
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
A ++V S P + PT + V EG+ + C V G
Sbjct: 2410 RVLG--SSVPLEASVLVTIEPAGSVPALGVTPTVRIESSSSQVAEGQTLDLNCLVAGQAH 2467
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
+W K G + AR V +R+L +V+ D G Y V G EAS +
Sbjct: 2468 AQVTWHKRGGSL--PARHQVHGSR--LRLL---QVTPADSGEYVCRVVGSSGTQEASVLV 2520
Query: 185 EVITR-SGKFYGGL 197
+ R SG G+
Sbjct: 2521 TIQQRLSGSHSQGV 2534
Score = 39.1 bits (87), Expect = 0.012
Identities = 28/129 (21%), Positives = 45/129 (34%), Gaps = 11/129 (8%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G T++ C V G + W + + + L++ QVT D G Y C
Sbjct: 2167 EGQTLDLNCVVPGQAHAQVTWHKRG------GSLPARHQTHGSLLRLHQVTPADSGEYVC 2220
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
G +++ LV + P P + V EG+ + C V G
Sbjct: 2221 HVVGTSGPLEASV-LVTIEASVIPGP----IPPVRIESSSSTVAEGQTLDLSCVVAGQAH 2275
Query: 125 PWASWDKDG 133
+W K G
Sbjct: 2276 AQVTWYKRG 2284
Score = 37.5 bits (83), Expect = 0.036
Identities = 24/67 (35%), Positives = 28/67 (41%), Gaps = 1/67 (1%)
Query: 6 GDTVEFECQVTGNPDPD-IRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
G TV F C G P P I W I + + G L I+ V D+G YTC
Sbjct: 421 GQTVTFTCVAIGVPAPFLINWRLNWGHIPSQPRVTVTSEGGRGTLIIRDVKESDQGAYTC 480
Query: 65 EASNCLG 71
EA N G
Sbjct: 481 EAMNARG 487
Score = 33.1 bits (72), Expect = 0.78
Identities = 26/85 (30%), Positives = 34/85 (40%), Gaps = 3/85 (3%)
Query: 94 MAPTFYTYPFNKV-VEEGENVTFKCAVKGNPSPW-ASWDKDGSIITPSARITVKEKEEIM 151
M P T P + G+ VTF C G P+P+ +W + I R+TV E
Sbjct: 404 MPPQVVTPPRESIQASRGQTVTFTCVAIGVPAPFLINWRLNWGHIPSQPRVTV-TSEGGR 462
Query: 152 RILEIDEVSIEDVGIYRITVENELG 176
L I +V D G Y N G
Sbjct: 463 GTLIIRDVKESDQGAYTCEAMNARG 487
Score = 30.3 bits (65), Expect = 5.5
Identities = 24/102 (23%), Positives = 39/102 (38%), Gaps = 6/102 (5%)
Query: 90 PGRQMAPTFY-TYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKE 148
P AP +P +V +G + + +C V G + W ++ PS +
Sbjct: 1672 PETNQAPLVVEVHPARSIVPQGGSHSLRCQVSGRGPHYFYWSREDGRPVPSGTQQRHQGS 1731
Query: 149 EIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVITRS 190
E L V D G+Y T N L R+ S ++T +
Sbjct: 1732 E----LHFPSVQPSDAGVYICTCRN-LHRSNTSRAELLVTEA 1768
>X57122-1|CAA40404.1| 731|Homo sapiens Fibroblast Growth Factor
Receptor, 2 Ig-Domain Form protein.
Length = 731
Score = 68.1 bits (159), Expect = 2e-11
Identities = 59/197 (29%), Positives = 82/197 (41%), Gaps = 27/197 (13%)
Query: 8 TVEFECQVTGNPDPDIRWFHYAEVIRD---CADFESSYDDGTARLKIKQVTAEDEGTYTC 64
TV+F+C +G P+P +RW + + ++ Y T + + V D+G YTC
Sbjct: 82 TVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRY--ATWSIIMDSVVPSDKGNYTC 139
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
N G L V SP R + P NK V G NV F C V +P
Sbjct: 140 IVENEYGSINHTYQLDVVER----SPHRPILQA--GLPANKTVALGSNVEFMCKVYSDPQ 193
Query: 125 PWASWDK----DGSIITP----------SARITVKEKEEIMRILEIDEVSIEDVGIYRIT 170
P W K +GS I P +A + +KE M +L + VS ED G Y
Sbjct: 194 PHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKE--MEVLHLRNVSFEDAGEYTCL 251
Query: 171 VENELGRAEASARLEVI 187
N +G + SA L V+
Sbjct: 252 AGNSIGLSHHSAWLTVL 268
Score = 48.4 bits (110), Expect = 2e-05
Identities = 28/84 (33%), Positives = 38/84 (45%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
V + V FKC G P+P W K+G P RI + + +D V D G
Sbjct: 77 VPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGN 136
Query: 167 YRITVENELGRAEASARLEVITRS 190
Y VENE G + +L+V+ RS
Sbjct: 137 YTCIVENEYGSINHTYQLDVVERS 160
Score = 41.1 bits (92), Expect = 0.003
Identities = 29/90 (32%), Positives = 41/90 (45%), Gaps = 15/90 (16%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEV--------------IRDCADFESSYDDGTARLKI 51
G VEF C+V +P P I+W + EV I A ++ D L +
Sbjct: 179 GSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTT-DKEMEVLHL 237
Query: 52 KQVTAEDEGTYTCEASNCLGKAKSNACLVV 81
+ V+ ED G YTC A N +G + +A L V
Sbjct: 238 RNVSFEDAGEYTCLAGNSIGLSHHSAWLTV 267
>X57121-1|CAA40403.1| 822|Homo sapiens Fibroblast Growth Factor
Receptor, 3-Ig Domain+2orm protein.
Length = 822
Score = 68.1 bits (159), Expect = 2e-11
Identities = 59/197 (29%), Positives = 82/197 (41%), Gaps = 27/197 (13%)
Query: 8 TVEFECQVTGNPDPDIRWFHYAEVIRD---CADFESSYDDGTARLKIKQVTAEDEGTYTC 64
TV+F+C +G P+P +RW + + ++ Y T + + V D+G YTC
Sbjct: 173 TVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRY--ATWSIIMDSVVPSDKGNYTC 230
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
N G L V SP R + P NK V G NV F C V +P
Sbjct: 231 IVENEYGSINHTYQLDVVER----SPHRPILQA--GLPANKTVALGSNVEFMCKVYSDPQ 284
Query: 125 PWASWDK----DGSIITP----------SARITVKEKEEIMRILEIDEVSIEDVGIYRIT 170
P W K +GS I P +A + +KE M +L + VS ED G Y
Sbjct: 285 PHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKE--MEVLHLRNVSFEDAGEYTCL 342
Query: 171 VENELGRAEASARLEVI 187
N +G + SA L V+
Sbjct: 343 AGNSIGLSHHSAWLTVL 359
Score = 48.8 bits (111), Expect = 1e-05
Identities = 32/108 (29%), Positives = 45/108 (41%), Gaps = 5/108 (4%)
Query: 88 SSPGRQMAPTFYTYPFNK-----VVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARI 142
+ P R ++T P V + V FKC G P+P W K+G P RI
Sbjct: 144 TKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRI 203
Query: 143 TVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVITRS 190
+ + +D V D G Y VENE G + +L+V+ RS
Sbjct: 204 GGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERS 251
Score = 41.1 bits (92), Expect = 0.003
Identities = 29/90 (32%), Positives = 41/90 (45%), Gaps = 15/90 (16%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEV--------------IRDCADFESSYDDGTARLKI 51
G VEF C+V +P P I+W + EV I A ++ D L +
Sbjct: 270 GSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTT-DKEMEVLHL 328
Query: 52 KQVTAEDEGTYTCEASNCLGKAKSNACLVV 81
+ V+ ED G YTC A N +G + +A L V
Sbjct: 329 RNVSFEDAGEYTCLAGNSIGLSHHSAWLTV 358
>X57120-1|CAA40402.1| 820|Homo sapiens Fibroblast Growth Factor
Receptor, 3 Ig-Domain Form protein.
Length = 820
Score = 68.1 bits (159), Expect = 2e-11
Identities = 59/197 (29%), Positives = 82/197 (41%), Gaps = 27/197 (13%)
Query: 8 TVEFECQVTGNPDPDIRWFHYAEVIRD---CADFESSYDDGTARLKIKQVTAEDEGTYTC 64
TV+F+C +G P+P +RW + + ++ Y T + + V D+G YTC
Sbjct: 171 TVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRY--ATWSIIMDSVVPSDKGNYTC 228
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
N G L V SP R + P NK V G NV F C V +P
Sbjct: 229 IVENEYGSINHTYQLDVVER----SPHRPILQA--GLPANKTVALGSNVEFMCKVYSDPQ 282
Query: 125 PWASWDK----DGSIITP----------SARITVKEKEEIMRILEIDEVSIEDVGIYRIT 170
P W K +GS I P +A + +KE M +L + VS ED G Y
Sbjct: 283 PHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKE--MEVLHLRNVSFEDAGEYTCL 340
Query: 171 VENELGRAEASARLEVI 187
N +G + SA L V+
Sbjct: 341 AGNSIGLSHHSAWLTVL 357
Score = 48.4 bits (110), Expect = 2e-05
Identities = 28/84 (33%), Positives = 38/84 (45%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
V + V FKC G P+P W K+G P RI + + +D V D G
Sbjct: 166 VPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGN 225
Query: 167 YRITVENELGRAEASARLEVITRS 190
Y VENE G + +L+V+ RS
Sbjct: 226 YTCIVENEYGSINHTYQLDVVERS 249
Score = 41.1 bits (92), Expect = 0.003
Identities = 29/90 (32%), Positives = 41/90 (45%), Gaps = 15/90 (16%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEV--------------IRDCADFESSYDDGTARLKI 51
G VEF C+V +P P I+W + EV I A ++ D L +
Sbjct: 268 GSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTT-DKEMEVLHL 326
Query: 52 KQVTAEDEGTYTCEASNCLGKAKSNACLVV 81
+ V+ ED G YTC A N +G + +A L V
Sbjct: 327 RNVSFEDAGEYTCLAGNSIGLSHHSAWLTV 356
>X57119-1|CAA40401.1| 733|Homo sapiens Fibroblast Growth Factor
Receptor, 2-Ig Domain+25-1 protein.
Length = 733
Score = 68.1 bits (159), Expect = 2e-11
Identities = 59/197 (29%), Positives = 82/197 (41%), Gaps = 27/197 (13%)
Query: 8 TVEFECQVTGNPDPDIRWFHYAEVIRD---CADFESSYDDGTARLKIKQVTAEDEGTYTC 64
TV+F+C +G P+P +RW + + ++ Y T + + V D+G YTC
Sbjct: 84 TVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRY--ATWSIIMDSVVPSDKGNYTC 141
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
N G L V SP R + P NK V G NV F C V +P
Sbjct: 142 IVENEYGSINHTYQLDVVER----SPHRPILQA--GLPANKTVALGSNVEFMCKVYSDPQ 195
Query: 125 PWASWDK----DGSIITP----------SARITVKEKEEIMRILEIDEVSIEDVGIYRIT 170
P W K +GS I P +A + +KE M +L + VS ED G Y
Sbjct: 196 PHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKE--MEVLHLRNVSFEDAGEYTCL 253
Query: 171 VENELGRAEASARLEVI 187
N +G + SA L V+
Sbjct: 254 AGNSIGLSHHSAWLTVL 270
Score = 48.8 bits (111), Expect = 1e-05
Identities = 32/108 (29%), Positives = 45/108 (41%), Gaps = 5/108 (4%)
Query: 88 SSPGRQMAPTFYTYPFNK-----VVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARI 142
+ P R ++T P V + V FKC G P+P W K+G P RI
Sbjct: 55 TKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRI 114
Query: 143 TVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVITRS 190
+ + +D V D G Y VENE G + +L+V+ RS
Sbjct: 115 GGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERS 162
Score = 41.1 bits (92), Expect = 0.003
Identities = 29/90 (32%), Positives = 41/90 (45%), Gaps = 15/90 (16%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEV--------------IRDCADFESSYDDGTARLKI 51
G VEF C+V +P P I+W + EV I A ++ D L +
Sbjct: 181 GSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTT-DKEMEVLHL 239
Query: 52 KQVTAEDEGTYTCEASNCLGKAKSNACLVV 81
+ V+ ED G YTC A N +G + +A L V
Sbjct: 240 RNVSFEDAGEYTCLAGNSIGLSHHSAWLTV 269
>X52833-1|CAA37015.1| 822|Homo sapiens protein ( Human flg mRNA for
fibroblast growth factor receptor-FLG. ).
Length = 822
Score = 68.1 bits (159), Expect = 2e-11
Identities = 59/197 (29%), Positives = 82/197 (41%), Gaps = 27/197 (13%)
Query: 8 TVEFECQVTGNPDPDIRWFHYAEVIRD---CADFESSYDDGTARLKIKQVTAEDEGTYTC 64
TV+F+C +G P+P +RW + + ++ Y T + + V D+G YTC
Sbjct: 173 TVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRY--ATWSIIMDSVVPSDKGNYTC 230
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
N G L V SP R + P NK V G NV F C V +P
Sbjct: 231 IVENEYGSINHTYQLDVVER----SPHRPILQA--GLPANKTVALGSNVEFMCKVYSDPQ 284
Query: 125 PWASWDK----DGSIITP----------SARITVKEKEEIMRILEIDEVSIEDVGIYRIT 170
P W K +GS I P +A + +KE M +L + VS ED G Y
Sbjct: 285 PHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKE--MEVLHLRNVSFEDAGEYTCL 342
Query: 171 VENELGRAEASARLEVI 187
N +G + SA L V+
Sbjct: 343 AGNSIGLSHHSAWLTVL 359
Score = 48.8 bits (111), Expect = 1e-05
Identities = 32/108 (29%), Positives = 45/108 (41%), Gaps = 5/108 (4%)
Query: 88 SSPGRQMAPTFYTYPFNK-----VVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARI 142
+ P R ++T P V + V FKC G P+P W K+G P RI
Sbjct: 144 TKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRI 203
Query: 143 TVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVITRS 190
+ + +D V D G Y VENE G + +L+V+ RS
Sbjct: 204 GGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERS 251
Score = 41.1 bits (92), Expect = 0.003
Identities = 29/90 (32%), Positives = 41/90 (45%), Gaps = 15/90 (16%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEV--------------IRDCADFESSYDDGTARLKI 51
G VEF C+V +P P I+W + EV I A ++ D L +
Sbjct: 270 GSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTT-DKEMEVLHL 328
Query: 52 KQVTAEDEGTYTCEASNCLGKAKSNACLVV 81
+ V+ ED G YTC A N +G + +A L V
Sbjct: 329 RNVSFEDAGEYTCLAGNSIGLSHHSAWLTV 358
>X51803-1|CAA36101.1| 822|Homo sapiens protein ( Human mRNA for
fibroblast growth factor (FGF) receptor. ).
Length = 822
Score = 68.1 bits (159), Expect = 2e-11
Identities = 59/197 (29%), Positives = 82/197 (41%), Gaps = 27/197 (13%)
Query: 8 TVEFECQVTGNPDPDIRWFHYAEVIRD---CADFESSYDDGTARLKIKQVTAEDEGTYTC 64
TV+F+C +G P+P +RW + + ++ Y T + + V D+G YTC
Sbjct: 173 TVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRY--ATWSIIMDSVVPSDKGNYTC 230
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
N G L V SP R + P NK V G NV F C V +P
Sbjct: 231 IVENEYGSINHTYQLDVVER----SPHRPILQA--GLPANKTVALGSNVEFMCKVYSDPQ 284
Query: 125 PWASWDK----DGSIITP----------SARITVKEKEEIMRILEIDEVSIEDVGIYRIT 170
P W K +GS I P +A + +KE M +L + VS ED G Y
Sbjct: 285 PHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKE--MEVLHLRNVSFEDAGEYTCL 342
Query: 171 VENELGRAEASARLEVI 187
N +G + SA L V+
Sbjct: 343 AGNSIGLSHHSAWLTVL 359
Score = 48.8 bits (111), Expect = 1e-05
Identities = 32/108 (29%), Positives = 45/108 (41%), Gaps = 5/108 (4%)
Query: 88 SSPGRQMAPTFYTYPFNK-----VVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARI 142
+ P R ++T P V + V FKC G P+P W K+G P RI
Sbjct: 144 TKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRI 203
Query: 143 TVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVITRS 190
+ + +D V D G Y VENE G + +L+V+ RS
Sbjct: 204 GGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERS 251
Score = 41.1 bits (92), Expect = 0.003
Identities = 29/90 (32%), Positives = 41/90 (45%), Gaps = 15/90 (16%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEV--------------IRDCADFESSYDDGTARLKI 51
G VEF C+V +P P I+W + EV I A ++ D L +
Sbjct: 270 GSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTT-DKEMEVLHL 328
Query: 52 KQVTAEDEGTYTCEASNCLGKAKSNACLVV 81
+ V+ ED G YTC A N +G + +A L V
Sbjct: 329 RNVSFEDAGEYTCLAGNSIGLSHHSAWLTV 358
>U75330-1|AAB80803.1| 837|Homo sapiens neural cell adhesion protein
protein.
Length = 837
Score = 68.1 bits (159), Expect = 2e-11
Identities = 47/186 (25%), Positives = 78/186 (41%), Gaps = 15/186 (8%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+ E C+V+ +P P + W ++ E + +D + L+I + DEG Y CE
Sbjct: 129 GEDAEVVCRVSSSPAPAVSWLYHNEEVTTISDNRLAMLANN-NLQILNINKSDEGIYRCE 187
Query: 66 AS-NCLGKAKSNACLVVYHTR-RLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
G+ +V+ + +S P + FN E GE +TF C G+P
Sbjct: 188 GRVEARGEIDFRDIIVIVNVPPAISMPQKS---------FNATAERGEEMTFSCRASGSP 238
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
P SW ++G +I + + +K + + I D G Y N+ G E A
Sbjct: 239 EPAISWFRNGKLIEENEKYILKGSNTELTVRNIIN---SDGGPYVCRATNKAGEDEKQAF 295
Query: 184 LEVITR 189
L+V +
Sbjct: 296 LQVFVQ 301
Score = 59.7 bits (138), Expect = 8e-09
Identities = 47/188 (25%), Positives = 77/188 (40%), Gaps = 22/188 (11%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+ + F C+ +G+P+P I WF ++I + + L ++ + D G Y C
Sbjct: 225 GEEMTFSCRASGSPEPAISWFRNGKLIEENEKY--ILKGSNTELTVRNIINSDGGPYVCR 282
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A+N G+ + A L V+ + P E G+ VT C +G P P
Sbjct: 283 ATNKAGEDEKQAFLQVF-----------VQPHIIQLKNETTYENGQ-VTLVCDAEGEPIP 330
Query: 126 WASWDK--DGSIIT-----PSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRA 178
+W + DG T P RI VK + L I +V + G Y + +G
Sbjct: 331 EITWKRAVDGFTFTEGDKSPDGRIEVKGQHG-SSSLHIKDVKLSGSGRYDCEAASRIGGH 389
Query: 179 EASARLEV 186
+ S L++
Sbjct: 390 QKSMYLDI 397
Score = 52.4 bits (120), Expect = 1e-06
Identities = 48/177 (27%), Positives = 68/177 (38%), Gaps = 21/177 (11%)
Query: 9 VEFECQVTGNPDPDIRW------FHYAEVIRDC-ADFESSYDDGTARLKIKQVTAEDEGT 61
V C G P P+I W F + E + E G++ L IK V G
Sbjct: 318 VTLVCDAEGEPIPEITWKRAVDGFTFTEGDKSPDGRIEVKGQHGSSSLHIKDVKLSGSGR 377
Query: 62 YTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKG 121
Y CEA++ +G + + L + + AP F + EG + C VK
Sbjct: 378 YDCEAASRIGGHQKSMYLDI-----------EYAPKFISNQTIYYSWEGNPINISCDVKS 426
Query: 122 NPSPWASWDKDGSIITPSARITVKEKEEIMR--ILEIDEVSIEDVGIYRITVENELG 176
NP W +D ++ P+ T + R ILEI S D G Y T N +G
Sbjct: 427 NPPASIHWRRD-KLVLPAKNTTNLKTYSTGRKMILEIAPTSDNDFGRYNCTATNHIG 482
Score = 40.7 bits (91), Expect = 0.004
Identities = 46/182 (25%), Positives = 74/182 (40%), Gaps = 21/182 (11%)
Query: 6 GDTVEFECQVTGNPDPDIRWFH-YAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
G++ F C G P I W++ E I +RL I ED G Y C
Sbjct: 35 GESKFFTCTAIGEPR-SIDWYNPQGEKIISTQRVVVQKGGVRSRLTIYNANIEDAGIYRC 93
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
+A++ G+ + A +V+ ++L TF + ++GE+ C V +P+
Sbjct: 94 QATDAKGQTQ-EATVVLEIYQKL---------TFREVVSPQEFKQGEDAEVVCRVSSSPA 143
Query: 125 PWASW-DKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
P SW + + T S ++IL I++ D GIYR GR EA
Sbjct: 144 PAVSWLYHNEEVTTISDNRLAMLANNNLQILNINK---SDEGIYRCE-----GRVEARGE 195
Query: 184 LE 185
++
Sbjct: 196 ID 197
Score = 32.7 bits (71), Expect = 1.0
Identities = 18/71 (25%), Positives = 31/71 (43%), Gaps = 2/71 (2%)
Query: 3 SCDGDTVEFECQVTGNPDPDIRWFHYAEVI--RDCADFESSYDDGTARLKIKQVTAEDEG 60
S +G+ + C V NP I W V+ ++ + ++ L+I + D G
Sbjct: 412 SWEGNPINISCDVKSNPPASIHWRRDKLVLPAKNTTNLKTYSTGRKMILEIAPTSDNDFG 471
Query: 61 TYTCEASNCLG 71
Y C A+N +G
Sbjct: 472 RYNCTATNHIG 482
>M85289-1|AAA52700.1| 4391|Homo sapiens heparan sulfate proteoglycan
protein.
Length = 4391
Score = 68.1 bits (159), Expect = 2e-11
Identities = 54/181 (29%), Positives = 81/181 (44%), Gaps = 24/181 (13%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G T C TG+P P I W +R ++ + T L I +V +D G Y C
Sbjct: 3226 GHTATLRCSATGSPAPTIHW----SKLRSPLPWQHRLEGDT--LIIPRVAQQDSGQYICN 3279
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A++ G A++ ++ H + SP P T P + V+ GE V +C G P
Sbjct: 3280 ATSPAGHAEAT---IILH---VESP-----PYATTVPEHASVQAGETVQLQCLAHGTPPL 3328
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
W + GS + R T + + +L + + ED G YR V N++G AEA A+L
Sbjct: 3329 TFQWSRVGSSLP--GRATARNE-----LLHFERAAPEDSGRYRCRVTNKVGSAEAFAQLL 3381
Query: 186 V 186
V
Sbjct: 3382 V 3382
Score = 67.7 bits (158), Expect = 3e-11
Identities = 55/185 (29%), Positives = 76/185 (41%), Gaps = 27/185 (14%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G VEFEC G+P P + W +R G ++I V D G Y C
Sbjct: 3503 GHAVEFECLALGDPKPQVTWSKVGGHLRP-----GIVQSGGV-VRIAHVELADAGQYRCT 3556
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A+N G +S+ L+V ++S P P G F C G P+P
Sbjct: 3557 ATNAAGTTQSHVLLLVQALPQISMPQEVRVPA------------GSAAVFPCIASGYPTP 3604
Query: 126 WASWDK-DGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
SW K DGS + P +R+ E +M + V +D G Y T N G+ +A A L
Sbjct: 3605 DISWSKLDGS-LPPDSRL---ENNMLM----LPSVRPQDAGTYVCTATNRQGKVKAFAHL 3656
Query: 185 EVITR 189
+V R
Sbjct: 3657 QVPER 3661
Score = 65.3 bits (152), Expect = 2e-10
Identities = 53/199 (26%), Positives = 81/199 (40%), Gaps = 18/199 (9%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G EF C TG+P P + W ++ G RL + T D+ Y C
Sbjct: 1880 GQLAEFRCSATGSPTPTLEW---TGGPGGQLPAKAQIHGGILRLPAVEPT--DQAQYLCR 1934
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A + G+ + A V H P Q++P V G V C G PS
Sbjct: 1935 AHSSAGQQVARA---VLHVHGGGGPRVQVSPE------RTQVHAGRTVRLYCRAAGVPSA 1985
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
+W K+G + P AR E+ +I +L I ++ D G Y + G A+A ++
Sbjct: 1986 TITWRKEGGSLPPQAR---SERTDIATLL-IPAITTADAGFYLCVATSPAGTAQARMQVV 2041
Query: 186 VITRSGKFYGGLRAYSASP 204
V++ S G++ S+SP
Sbjct: 2042 VLSASDASPPGVKIESSSP 2060
Score = 64.1 bits (149), Expect = 4e-10
Identities = 51/181 (28%), Positives = 70/181 (38%), Gaps = 12/181 (6%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G V EC G P RW + D A L+I D GTY C
Sbjct: 3127 GKAVTLECVSAGEPRSSARWTRISSTPAKLEQRTYGLMDSHAVLQISSAKPSDAGTYVCL 3186
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A N LG A+ ++V +PG AP VE G T +C+ G+P+P
Sbjct: 3187 AQNALGTAQKQVEVIV--DTGAMAPG---APQVQAEEAELTVEAGHTATLRCSATGSPAP 3241
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
W K S + R+ E + ++ I V+ +D G Y + G AEA+ L
Sbjct: 3242 TIHWSKLRSPLPWQHRL---EGDTLI----IPRVAQQDSGQYICNATSPAGHAEATIILH 3294
Query: 186 V 186
V
Sbjct: 3295 V 3295
Score = 62.1 bits (144), Expect = 1e-09
Identities = 51/181 (28%), Positives = 80/181 (44%), Gaps = 22/181 (12%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G +VEF C V + +RWF + S DG L+I+ + +GTY C+
Sbjct: 3414 GASVEFHCAVPSDQGTQLRWFKEGGQLPP----GHSVQDGV--LRIQNLDQSCQGTYICQ 3467
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A GKA+++A LV+ + L S + + T V G V F+C G+P P
Sbjct: 3468 AHGPWGKAQASAQLVI---QALPSVLINIRTSVQT------VVVGHAVEFECLALGDPKP 3518
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
+W K G + P + + ++RI ++ + D G YR T N G ++ L
Sbjct: 3519 QVTWSKVGGHLRPG----IVQSGGVVRIAHVE---LADAGQYRCTATNAAGTTQSHVLLL 3571
Query: 186 V 186
V
Sbjct: 3572 V 3572
Score = 60.5 bits (140), Expect = 5e-09
Identities = 53/191 (27%), Positives = 78/191 (40%), Gaps = 18/191 (9%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G TV C+ G P I W + A E + A L I +T D G Y C
Sbjct: 1970 GRTVRLYCRAAGVPSATITWRKEGGSLPPQARSERT---DIATLLIPAITTADAGFYLCV 2026
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A++ G A++ +VV S PG ++ + + V EG+ + C V G+
Sbjct: 2027 ATSPAGTAQARMQVVVLSASDASPPGVKIESS------SPSVTEGQTLDLNCVVAGSAHA 2080
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
+W + G + P ++ L + +VS D G Y VEN G EAS +
Sbjct: 2081 QVTWYRRGGSLPPHTQVHGSR-------LRLPQVSPADSGEYVCRVENGSGPKEASITVS 2133
Query: 186 VI--TRSGKFY 194
V+ T SG Y
Sbjct: 2134 VLHGTHSGPSY 2144
Score = 56.0 bits (129), Expect = 1e-07
Identities = 46/184 (25%), Positives = 78/184 (42%), Gaps = 16/184 (8%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+TV+ +C G P +W + A + L ++ ED G Y C
Sbjct: 3313 GETVQLQCLAHGTPPLTFQWSRVGSSLPGRATARNEL------LHFERAAPEDSGRYRCR 3366
Query: 66 ASNCLGKAKSNACLVVYH---TRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGN 122
+N +G A++ A L+V + +S PT P + G +V F CAV +
Sbjct: 3367 VTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQVTPQLETKSIGASVEFHCAVPSD 3426
Query: 123 PSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASA 182
W K+G + P + ++ ++RI +D+ S + G Y G+A+ASA
Sbjct: 3427 QGTQLRWFKEGGQLPPGHSV----QDGVLRIQNLDQ-SCQ--GTYICQAHGPWGKAQASA 3479
Query: 183 RLEV 186
+L +
Sbjct: 3480 QLVI 3483
Score = 55.6 bits (128), Expect = 1e-07
Identities = 48/187 (25%), Positives = 73/187 (39%), Gaps = 15/187 (8%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G T++ C V I W+ S + +RL+I QVT D G Y C
Sbjct: 2547 NGHTLDLNCLVASQAPHTITWYKRG------GSLPSRHQIVGSRLRIPQVTPADSGEYVC 2600
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
SN G +++ L+V SS ++P + V EG+ + C V P
Sbjct: 2601 HVSNGAGSRETS--LIVTIQGSGSSHVPSVSPPIRIESSSPTVVEGQTLDLNCVVARQPQ 2658
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
+W K G + PS T L + ++S+ D G Y N + EAS +
Sbjct: 2659 AIITWYKRGGSL-PSRHQTHGSH------LRLHQMSVADSGEYVCRANNNIDALEASIVI 2711
Query: 185 EVITRSG 191
V +G
Sbjct: 2712 SVSPSAG 2718
Score = 54.4 bits (125), Expect = 3e-07
Identities = 43/184 (23%), Positives = 71/184 (38%), Gaps = 15/184 (8%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G+T++ C V G + W S + +RL++ V+ D G Y C
Sbjct: 2740 EGETLDLNCVVPGQAHAQVTWHKRG------GSLPSHHQTRGSRLRLHHVSPADSGEYVC 2793
Query: 65 EASNCLGKAKSNACLVVYHT--RRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGN 122
G +++ + + + + P AP P + V EG+ + KC V G
Sbjct: 2794 RVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPIRIEPSSSRVAEGQTLDLKCVVPGQ 2853
Query: 123 PSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASA 182
+W K G + AR V +L +++VS D G Y V G EAS
Sbjct: 2854 AHAQVTWHKRGGNL--PARHQVHGP-----LLRLNQVSPADSGEYSCQVTGSSGTLEASV 2906
Query: 183 RLEV 186
+ +
Sbjct: 2907 LVTI 2910
Score = 51.6 bits (118), Expect = 2e-06
Identities = 49/188 (26%), Positives = 74/188 (39%), Gaps = 17/188 (9%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G T++ C V P I W+ S + + L++ Q++ D G Y C
Sbjct: 2643 EGQTLDLNCVVARQPQAIITWYKRG------GSLPSRHQTHGSHLRLHQMSVADSGEYVC 2696
Query: 65 EASNCLGKAKSNACLVVYHTRRL-SSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
A+N + +++ + V + S+PG M + + V EGE + C V G
Sbjct: 2697 RANNNIDALEASIVISVSPSAGSPSAPGSSMPIRIESSSSH--VAEGETLDLNCVVPGQA 2754
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
+W K G + PS T + L + VS D G Y V G EAS
Sbjct: 2755 HAQVTWHKRGGSL-PSHHQTRGSR------LRLHHVSPADSGEYVCRVMGSSGPLEASV- 2806
Query: 184 LEVITRSG 191
L I SG
Sbjct: 2807 LVTIEASG 2814
Score = 50.8 bits (116), Expect = 4e-06
Identities = 44/186 (23%), Positives = 70/186 (37%), Gaps = 18/186 (9%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G T++ C V G+ + W+ + S RL++ QV+ D G Y C
Sbjct: 2064 EGQTLDLNCVVAGSAHAQVTWYRRGGSLPPHTQVHGS------RLRLPQVSPADSGEYVC 2117
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAP----TFYTYPFNKVVEEGENVTFKCAVK 120
N G +++ + V H S P P P + V EG+ + C V
Sbjct: 2118 RVENGSGPKEASITVSVLHGTH-SGPSYTPVPGSTRPIRIEPSSSHVAEGQTLDLNCVVP 2176
Query: 121 GNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEA 180
G +W K G + P+ T +L + +V+ D G Y V G EA
Sbjct: 2177 GQAHAQVTWHKRGGSL-PARHQTHGS------LLRLHQVTPADSGEYVCHVVGTSGPLEA 2229
Query: 181 SARLEV 186
S + +
Sbjct: 2230 SVLVTI 2235
Score = 46.4 bits (105), Expect = 8e-05
Identities = 26/81 (32%), Positives = 36/81 (44%), Gaps = 6/81 (7%)
Query: 49 LKIKQVTAEDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVE 108
L I+ V D GTY C SN + A L V + LS AP +P V+
Sbjct: 1825 LTIRNVQLSDAGTYVCTGSNMFAMDQGTATLHVQASGTLS------APVVSIHPPQLTVQ 1878
Query: 109 EGENVTFKCAVKGNPSPWASW 129
G+ F+C+ G+P+P W
Sbjct: 1879 PGQLAEFRCSATGSPTPTLEW 1899
Score = 46.4 bits (105), Expect = 8e-05
Identities = 38/183 (20%), Positives = 71/183 (38%), Gaps = 13/183 (7%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G T++ C V G + W+ + + ++L++ V+ D G Y C
Sbjct: 2938 EGQTLDLNCVVPGQAHAQVTWYKRG------GSLPARHQTHGSQLRLHLVSPADSGEYVC 2991
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
A++ G + + V SS R +P P + V++G++ +FKC + +
Sbjct: 2992 RAASGPGPEQEASFTVTVPPSEGSSY-RLRSPVISIDPPSSTVQQGQDASFKCLIHDGAA 3050
Query: 125 PWA-SWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
P + W + + I+ I+ I + G YR N G A++
Sbjct: 3051 PISLEWKTRNQELEDNVHISPNGS-----IITIVGTRPSNHGTYRCVASNAYGVAQSVVN 3105
Query: 184 LEV 186
L V
Sbjct: 3106 LSV 3108
Score = 46.0 bits (104), Expect = 1e-04
Identities = 26/129 (20%), Positives = 51/129 (39%), Gaps = 6/129 (4%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G T++ +C V G + W + + + L++ QV+ D G Y+C
Sbjct: 2840 EGQTLDLKCVVPGQAHAQVTWHKRG------GNLPARHQVHGPLLRLNQVSPADSGEYSC 2893
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
+ + G +++ + + + P +A Y + V EG+ + C V G
Sbjct: 2894 QVTGSSGTLEASVLVTIEPSSPGPIPAPGLAQPIYIEASSSHVTEGQTLDLNCVVPGQAH 2953
Query: 125 PWASWDKDG 133
+W K G
Sbjct: 2954 AQVTWYKRG 2962
Score = 45.2 bits (102), Expect = 2e-04
Identities = 31/129 (24%), Positives = 48/129 (37%), Gaps = 8/129 (6%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G T++ C V G + W+ + + +RL I Q + D G Y C
Sbjct: 2258 EGQTLDLSCVVAGQAHAQVTWYKRG------GSLPARHQVRGSRLYIFQASPADAGQYVC 2311
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
ASN + +A + L+ P P P + V EG+ + C V G
Sbjct: 2312 RASNGM-EASITVTVTGTQGANLAYPAGSTQP-IRIEPSSSQVAEGQTLDLNCVVPGQSH 2369
Query: 125 PWASWDKDG 133
+W K G
Sbjct: 2370 AQVTWHKRG 2378
Score = 44.4 bits (100), Expect = 3e-04
Identities = 42/140 (30%), Positives = 58/140 (41%), Gaps = 15/140 (10%)
Query: 58 DEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKV-VEEGENVTFK 116
+ GTY C ASN G A+S L V+ P PT P V V+ G+ VT +
Sbjct: 3085 NHGTYRCVASNAYGVAQSVVNLSVH------GP-----PTVSVLPEGPVWVKVGKAVTLE 3133
Query: 117 CAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG 176
C G P A W + S + T + +L+I D G Y +N LG
Sbjct: 3134 CVSAGEPRSSARWTRISSTPAKLEQRTYGLMDS-HAVLQISSAKPSDAGTYVCLAQNALG 3192
Query: 177 RAEASARLEVITRSGKFYGG 196
A+ ++EVI +G G
Sbjct: 3193 TAQ--KQVEVIVDTGAMAPG 3210
Score = 42.3 bits (95), Expect = 0.001
Identities = 24/66 (36%), Positives = 28/66 (42%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G TV F C G P P I W I + + G L I+ V D+G YTCE
Sbjct: 421 GQTVTFTCVAIGVPTPIINWRLNWGHIPSHPRVTVTSEGGRGTLIIRDVKESDQGAYTCE 480
Query: 66 ASNCLG 71
A N G
Sbjct: 481 AMNARG 486
Score = 39.9 bits (89), Expect = 0.007
Identities = 45/194 (23%), Positives = 69/194 (35%), Gaps = 16/194 (8%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G T++ C V G + W + + L++ Q + D G Y C
Sbjct: 2354 EGQTLDLNCVVPGQSHAQVTWHKRG------GSLPVRHQTHGSLLRLYQASPADSGEYVC 2407
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
A ++V S P + PT + V EG+ + C V G
Sbjct: 2408 RVLG--SSVPLEASVLVTIEPAGSVPALGVTPTVRIESSSSQVAEGQTLDLNCLVAGQAH 2465
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
+W K G + AR V +R+L +V+ D G Y V G EAS +
Sbjct: 2466 AQVTWHKRGGSL--PARHQVHGSR--LRLL---QVTPADSGEYVCRVVGSSGTQEASVLV 2518
Query: 185 EVITR-SGKFYGGL 197
+ R SG G+
Sbjct: 2519 TIQQRLSGSHSQGV 2532
Score = 39.1 bits (87), Expect = 0.012
Identities = 28/129 (21%), Positives = 45/129 (34%), Gaps = 11/129 (8%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G T++ C V G + W + + + L++ QVT D G Y C
Sbjct: 2165 EGQTLDLNCVVPGQAHAQVTWHKRG------GSLPARHQTHGSLLRLHQVTPADSGEYVC 2218
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
G +++ LV + P P + V EG+ + C V G
Sbjct: 2219 HVVGTSGPLEASV-LVTIEASVIPGP----IPPVRIESSSSTVAEGQTLDLSCVVAGQAH 2273
Query: 125 PWASWDKDG 133
+W K G
Sbjct: 2274 AQVTWYKRG 2282
Score = 35.5 bits (78), Expect = 0.15
Identities = 26/84 (30%), Positives = 33/84 (39%), Gaps = 2/84 (2%)
Query: 94 MAPTFYTYPFNKV-VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMR 152
M P T P + G+ VTF C G P+P +W + I R+TV E
Sbjct: 404 MPPQVVTPPRESIQASRGQTVTFTCVAIGVPTPIINWRLNWGHIPSHPRVTV-TSEGGRG 462
Query: 153 ILEIDEVSIEDVGIYRITVENELG 176
L I +V D G Y N G
Sbjct: 463 TLIIRDVKESDQGAYTCEAMNARG 486
Score = 33.1 bits (72), Expect = 0.78
Identities = 21/85 (24%), Positives = 33/85 (38%), Gaps = 5/85 (5%)
Query: 90 PGRQMAPTFY-TYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKE 148
P AP +P +V +G + + +C V G+P + W ++ PS +
Sbjct: 1670 PETNQAPLVVEVHPARSIVPQGGSHSLRCQVSGSPPHYFYWSREDGRPVPSGTQQRHQGS 1729
Query: 149 EIMRILEIDEVSIEDVGIYRITVEN 173
E L V D G+Y T N
Sbjct: 1730 E----LHFPSVQPSDAGVYICTCRN 1750
>M60485-1|AAA35840.1| 820|Homo sapiens fibroblast growth factor
receptor protein.
Length = 820
Score = 68.1 bits (159), Expect = 2e-11
Identities = 59/197 (29%), Positives = 82/197 (41%), Gaps = 27/197 (13%)
Query: 8 TVEFECQVTGNPDPDIRWFHYAEVIRD---CADFESSYDDGTARLKIKQVTAEDEGTYTC 64
TV+F+C +G P+P +RW + + ++ Y T + + V D+G YTC
Sbjct: 171 TVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRY--ATWSIIMDSVVPSDKGNYTC 228
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
N G L V SP R + P NK V G NV F C V +P
Sbjct: 229 IVENEYGSINHTYQLDVVER----SPHRPILQA--GLPANKTVALGSNVEFMCKVYSDPQ 282
Query: 125 PWASWDK----DGSIITP----------SARITVKEKEEIMRILEIDEVSIEDVGIYRIT 170
P W K +GS I P +A + +KE M +L + VS ED G Y
Sbjct: 283 PHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKE--MEVLHLRNVSFEDAGEYTCL 340
Query: 171 VENELGRAEASARLEVI 187
N +G + SA L V+
Sbjct: 341 AGNSIGLSHHSAWLTVL 357
Score = 48.4 bits (110), Expect = 2e-05
Identities = 28/84 (33%), Positives = 38/84 (45%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
V + V FKC G P+P W K+G P RI + + +D V D G
Sbjct: 166 VPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGN 225
Query: 167 YRITVENELGRAEASARLEVITRS 190
Y VENE G + +L+V+ RS
Sbjct: 226 YTCIVENEYGSINHTYQLDVVERS 249
Score = 41.1 bits (92), Expect = 0.003
Identities = 29/90 (32%), Positives = 41/90 (45%), Gaps = 15/90 (16%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEV--------------IRDCADFESSYDDGTARLKI 51
G VEF C+V +P P I+W + EV I A ++ D L +
Sbjct: 268 GSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTT-DKEMEVLHL 326
Query: 52 KQVTAEDEGTYTCEASNCLGKAKSNACLVV 81
+ V+ ED G YTC A N +G + +A L V
Sbjct: 327 RNVSFEDAGEYTCLAGNSIGLSHHSAWLTV 356
>M37722-1|AAA75007.1| 731|Homo sapiens basic fibroblast growth
factor receptor protein protein.
Length = 731
Score = 68.1 bits (159), Expect = 2e-11
Identities = 59/197 (29%), Positives = 82/197 (41%), Gaps = 27/197 (13%)
Query: 8 TVEFECQVTGNPDPDIRWFHYAEVIRD---CADFESSYDDGTARLKIKQVTAEDEGTYTC 64
TV+F+C +G P+P +RW + + ++ Y T + + V D+G YTC
Sbjct: 82 TVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRY--ATWSIIMDSVVPSDKGNYTC 139
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
N G L V SP R + P NK V G NV F C V +P
Sbjct: 140 IVENEYGSINHTYQLDVVER----SPHRPILQA--GLPANKTVALGSNVEFMCKVYSDPQ 193
Query: 125 PWASWDK----DGSIITP----------SARITVKEKEEIMRILEIDEVSIEDVGIYRIT 170
P W K +GS I P +A + +KE M +L + VS ED G Y
Sbjct: 194 PHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKE--MEVLHLRNVSFEDAGEYTCL 251
Query: 171 VENELGRAEASARLEVI 187
N +G + SA L V+
Sbjct: 252 AGNSIGLSHHSAWLTVL 268
Score = 48.4 bits (110), Expect = 2e-05
Identities = 28/84 (33%), Positives = 38/84 (45%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
V + V FKC G P+P W K+G P RI + + +D V D G
Sbjct: 77 VPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGN 136
Query: 167 YRITVENELGRAEASARLEVITRS 190
Y VENE G + +L+V+ RS
Sbjct: 137 YTCIVENEYGSINHTYQLDVVERS 160
Score = 41.1 bits (92), Expect = 0.003
Identities = 29/90 (32%), Positives = 41/90 (45%), Gaps = 15/90 (16%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEV--------------IRDCADFESSYDDGTARLKI 51
G VEF C+V +P P I+W + EV I A ++ D L +
Sbjct: 179 GSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTT-DKEMEVLHL 237
Query: 52 KQVTAEDEGTYTCEASNCLGKAKSNACLVV 81
+ V+ ED G YTC A N +G + +A L V
Sbjct: 238 RNVSFEDAGEYTCLAGNSIGLSHHSAWLTV 267
>M34185-1|AAA35836.1| 733|Homo sapiens protein ( Human fibroblast
growth factor receptor (FGFr) transmembrane form mRNA,
complete cds. ).
Length = 733
Score = 68.1 bits (159), Expect = 2e-11
Identities = 59/197 (29%), Positives = 82/197 (41%), Gaps = 27/197 (13%)
Query: 8 TVEFECQVTGNPDPDIRWFHYAEVIRD---CADFESSYDDGTARLKIKQVTAEDEGTYTC 64
TV+F+C +G P+P +RW + + ++ Y T + + V D+G YTC
Sbjct: 84 TVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRY--ATWSIIMDSVVPSDKGNYTC 141
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
N G L V SP R + P NK V G NV F C V +P
Sbjct: 142 IVENEYGSINHTYQLDVVER----SPHRPILQA--GLPANKTVALGSNVEFMCKVYSDPQ 195
Query: 125 PWASWDK----DGSIITP----------SARITVKEKEEIMRILEIDEVSIEDVGIYRIT 170
P W K +GS I P +A + +KE M +L + VS ED G Y
Sbjct: 196 PHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKE--MEVLHLRNVSFEDAGEYTCL 253
Query: 171 VENELGRAEASARLEVI 187
N +G + SA L V+
Sbjct: 254 AGNSIGLSHHSAWLTVL 270
Score = 48.8 bits (111), Expect = 1e-05
Identities = 32/108 (29%), Positives = 45/108 (41%), Gaps = 5/108 (4%)
Query: 88 SSPGRQMAPTFYTYPFNK-----VVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARI 142
+ P R ++T P V + V FKC G P+P W K+G P RI
Sbjct: 55 TKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRI 114
Query: 143 TVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVITRS 190
+ + +D V D G Y VENE G + +L+V+ RS
Sbjct: 115 GGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERS 162
Score = 41.1 bits (92), Expect = 0.003
Identities = 29/90 (32%), Positives = 41/90 (45%), Gaps = 15/90 (16%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEV--------------IRDCADFESSYDDGTARLKI 51
G VEF C+V +P P I+W + EV I A ++ D L +
Sbjct: 181 GSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTT-DKEMEVLHL 239
Query: 52 KQVTAEDEGTYTCEASNCLGKAKSNACLVV 81
+ V+ ED G YTC A N +G + +A L V
Sbjct: 240 RNVSFEDAGEYTCLAGNSIGLSHHSAWLTV 269
>BC091494-1|AAH91494.1| 731|Homo sapiens fibroblast growth factor
receptor 1 (fms-related tyrosine kinase 2, Pfeiffer sy
protein.
Length = 731
Score = 68.1 bits (159), Expect = 2e-11
Identities = 59/197 (29%), Positives = 82/197 (41%), Gaps = 27/197 (13%)
Query: 8 TVEFECQVTGNPDPDIRWFHYAEVIRD---CADFESSYDDGTARLKIKQVTAEDEGTYTC 64
TV+F+C +G P+P +RW + + ++ Y T + + V D+G YTC
Sbjct: 82 TVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRY--ATWSIIMDSVVPSDKGNYTC 139
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
N G L V SP R + P NK V G NV F C V +P
Sbjct: 140 IVENEYGSINHTYQLDVVER----SPHRPILQA--GLPANKTVALGSNVEFMCKVYSDPQ 193
Query: 125 PWASWDK----DGSIITP----------SARITVKEKEEIMRILEIDEVSIEDVGIYRIT 170
P W K +GS I P +A + +KE M +L + VS ED G Y
Sbjct: 194 PHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKE--MEVLHLRNVSFEDAGEYTCL 251
Query: 171 VENELGRAEASARLEVI 187
N +G + SA L V+
Sbjct: 252 AGNSIGLSHHSAWLTVL 268
Score = 48.4 bits (110), Expect = 2e-05
Identities = 28/84 (33%), Positives = 38/84 (45%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
V + V FKC G P+P W K+G P RI + + +D V D G
Sbjct: 77 VPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGN 136
Query: 167 YRITVENELGRAEASARLEVITRS 190
Y VENE G + +L+V+ RS
Sbjct: 137 YTCIVENEYGSINHTYQLDVVERS 160
Score = 41.1 bits (92), Expect = 0.003
Identities = 29/90 (32%), Positives = 41/90 (45%), Gaps = 15/90 (16%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEV--------------IRDCADFESSYDDGTARLKI 51
G VEF C+V +P P I+W + EV I A ++ D L +
Sbjct: 179 GSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTT-DKEMEVLHL 237
Query: 52 KQVTAEDEGTYTCEASNCLGKAKSNACLVV 81
+ V+ ED G YTC A N +G + +A L V
Sbjct: 238 RNVSFEDAGEYTCLAGNSIGLSHHSAWLTV 267
>BC052946-1|AAH52946.1| 837|Homo sapiens neural cell adhesion
molecule 2 protein.
Length = 837
Score = 68.1 bits (159), Expect = 2e-11
Identities = 47/186 (25%), Positives = 78/186 (41%), Gaps = 15/186 (8%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+ E C+V+ +P P + W ++ E + +D + L+I + DEG Y CE
Sbjct: 129 GEDAEVVCRVSSSPAPAVSWLYHNEEVTTISDNRFAMLANN-NLQILNINKSDEGIYRCE 187
Query: 66 AS-NCLGKAKSNACLVVYHTR-RLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
G+ +V+ + +S P + FN E GE +TF C G+P
Sbjct: 188 GRVEARGEIDFRDIIVIVNVPPAISMPQKS---------FNATAERGEEMTFSCRASGSP 238
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
P SW ++G +I + + +K + + I D G Y N+ G E A
Sbjct: 239 EPAISWFRNGKLIEENEKYILKGSNTELTVRNIIN---SDGGPYVCRATNKAGEDEKQAF 295
Query: 184 LEVITR 189
L+V +
Sbjct: 296 LQVFVQ 301
Score = 59.3 bits (137), Expect = 1e-08
Identities = 47/188 (25%), Positives = 77/188 (40%), Gaps = 22/188 (11%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+ + F C+ +G+P+P I WF ++I + + L ++ + D G Y C
Sbjct: 225 GEEMTFSCRASGSPEPAISWFRNGKLIEENEKY--ILKGSNTELTVRNIINSDGGPYVCR 282
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A+N G+ + A L V+ + P E G+ VT C +G P P
Sbjct: 283 ATNKAGEDEKQAFLQVF-----------VQPHIIQLKNETTYENGQ-VTLVCDAEGEPIP 330
Query: 126 WASWDK--DGSIITP-----SARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRA 178
+W + DG T RI VK + L I +V + D G Y + +G
Sbjct: 331 EITWKRAVDGFTFTEGDKSLDGRIEVKGQHG-SSSLHIKDVKLSDSGRYDCEAASRIGGH 389
Query: 179 EASARLEV 186
+ S L++
Sbjct: 390 QKSMYLDI 397
Score = 56.0 bits (129), Expect = 1e-07
Identities = 49/177 (27%), Positives = 69/177 (38%), Gaps = 21/177 (11%)
Query: 9 VEFECQVTGNPDPDIRW------FHYAEVIRDC-ADFESSYDDGTARLKIKQVTAEDEGT 61
V C G P P+I W F + E + E G++ L IK V D G
Sbjct: 318 VTLVCDAEGEPIPEITWKRAVDGFTFTEGDKSLDGRIEVKGQHGSSSLHIKDVKLSDSGR 377
Query: 62 YTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKG 121
Y CEA++ +G + + L + + AP F + EG + C VK
Sbjct: 378 YDCEAASRIGGHQKSMYLDI-----------EYAPKFISNQTIYYSWEGNPINISCDVKS 426
Query: 122 NPSPWASWDKDGSIITPSARITVKEKEEIMR--ILEIDEVSIEDVGIYRITVENELG 176
NP W +D ++ P+ T + R ILEI S D G Y T N +G
Sbjct: 427 NPPASIHWRRD-KLVLPAKNTTNLKTYSTGRKMILEIAPTSDNDFGRYNCTATNHIG 482
Score = 43.2 bits (97), Expect = 7e-04
Identities = 46/184 (25%), Positives = 76/184 (41%), Gaps = 25/184 (13%)
Query: 6 GDTVEFECQVTGNPDPDIRWFH-YAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
G++ F C G P+ I W++ E I + +RL I ED G Y C
Sbjct: 35 GESKFFTCTAIGEPE-SIDWYNPQGEKIISTQRVVVQKEGVRSRLTIYNANIEDAGIYRC 93
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
+A++ G+ + A +V+ ++L TF + ++GE+ C V +P+
Sbjct: 94 QATDAKGQTQ-EATVVLEIYQKL---------TFREVVSPQEFKQGEDAEVVCRVSSSPA 143
Query: 125 PWASWDKDGSIITPSARITVKEKEEIM---RILEIDEVSIEDVGIYRITVENELGRAEAS 181
P SW +T T+ + M L+I ++ D GIYR GR EA
Sbjct: 144 PAVSWLYHNEEVT-----TISDNRFAMLANNNLQILNINKSDEGIYRCE-----GRVEAR 193
Query: 182 ARLE 185
++
Sbjct: 194 GEID 197
Score = 41.1 bits (92), Expect = 0.003
Identities = 29/89 (32%), Positives = 43/89 (48%), Gaps = 3/89 (3%)
Query: 100 TYPFNKV-VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDE 158
T +KV + GE+ F C G P ++ G I + R+ V +KE + L I
Sbjct: 24 TISLSKVELSVGESKFFTCTAIGEPESIDWYNPQGEKIISTQRVVV-QKEGVRSRLTIYN 82
Query: 159 VSIEDVGIYRITVENELGRA-EASARLEV 186
+IED GIYR + G+ EA+ LE+
Sbjct: 83 ANIEDAGIYRCQATDAKGQTQEATVVLEI 111
Score = 32.7 bits (71), Expect = 1.0
Identities = 18/71 (25%), Positives = 31/71 (43%), Gaps = 2/71 (2%)
Query: 3 SCDGDTVEFECQVTGNPDPDIRWFHYAEVI--RDCADFESSYDDGTARLKIKQVTAEDEG 60
S +G+ + C V NP I W V+ ++ + ++ L+I + D G
Sbjct: 412 SWEGNPINISCDVKSNPPASIHWRRDKLVLPAKNTTNLKTYSTGRKMILEIAPTSDNDFG 471
Query: 61 TYTCEASNCLG 71
Y C A+N +G
Sbjct: 472 RYNCTATNHIG 482
>BC015035-1|AAH15035.1| 820|Homo sapiens FGFR1 protein protein.
Length = 820
Score = 68.1 bits (159), Expect = 2e-11
Identities = 59/197 (29%), Positives = 82/197 (41%), Gaps = 27/197 (13%)
Query: 8 TVEFECQVTGNPDPDIRWFHYAEVIRD---CADFESSYDDGTARLKIKQVTAEDEGTYTC 64
TV+F+C +G P+P +RW + + ++ Y T + + V D+G YTC
Sbjct: 173 TVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRY--ATWSIIMDSVVPSDKGNYTC 230
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
N G L V SP R + P NK V G NV F C V +P
Sbjct: 231 IVENEYGSINHTYQLDVVER----SPHRPILQA--GLPANKTVALGSNVEFMCKVYSDPQ 284
Query: 125 PWASWDK----DGSIITP----------SARITVKEKEEIMRILEIDEVSIEDVGIYRIT 170
P W K +GS I P +A + +KE M +L + VS ED G Y
Sbjct: 285 PHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKE--MEVLHLRNVSFEDAGEYTCL 342
Query: 171 VENELGRAEASARLEVI 187
N +G + SA L V+
Sbjct: 343 AGNSIGLSHHSAWLTVL 359
Score = 48.8 bits (111), Expect = 1e-05
Identities = 32/108 (29%), Positives = 45/108 (41%), Gaps = 5/108 (4%)
Query: 88 SSPGRQMAPTFYTYPFNK-----VVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARI 142
+ P R ++T P V + V FKC G P+P W K+G P RI
Sbjct: 144 TKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRI 203
Query: 143 TVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVITRS 190
+ + +D V D G Y VENE G + +L+V+ RS
Sbjct: 204 GGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERS 251
Score = 41.1 bits (92), Expect = 0.003
Identities = 29/90 (32%), Positives = 41/90 (45%), Gaps = 15/90 (16%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEV--------------IRDCADFESSYDDGTARLKI 51
G VEF C+V +P P I+W + EV I A ++ D L +
Sbjct: 270 GSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTT-DKEMEVLHL 328
Query: 52 KQVTAEDEGTYTCEASNCLGKAKSNACLVV 81
+ V+ ED G YTC A N +G + +A L V
Sbjct: 329 RNVSFEDAGEYTCLAGNSIGLSHHSAWLTV 358
>AY585209-1|AAS79322.1| 822|Homo sapiens fibroblast growth factor
receptor 1 (fms-related tyrosine kinase 2, Pfeiffer sy
protein.
Length = 822
Score = 68.1 bits (159), Expect = 2e-11
Identities = 59/197 (29%), Positives = 82/197 (41%), Gaps = 27/197 (13%)
Query: 8 TVEFECQVTGNPDPDIRWFHYAEVIRD---CADFESSYDDGTARLKIKQVTAEDEGTYTC 64
TV+F+C +G P+P +RW + + ++ Y T + + V D+G YTC
Sbjct: 173 TVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRY--ATWSIIMDSVVPSDKGNYTC 230
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
N G L V SP R + P NK V G NV F C V +P
Sbjct: 231 IVENEYGSINHTYQLDVVER----SPHRPILQA--GLPANKTVALGSNVEFMCKVYSDPQ 284
Query: 125 PWASWDK----DGSIITP----------SARITVKEKEEIMRILEIDEVSIEDVGIYRIT 170
P W K +GS I P +A + +KE M +L + VS ED G Y
Sbjct: 285 PHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKE--MEVLHLRNVSFEDAGEYTCL 342
Query: 171 VENELGRAEASARLEVI 187
N +G + SA L V+
Sbjct: 343 AGNSIGLSHHSAWLTVL 359
Score = 48.8 bits (111), Expect = 1e-05
Identities = 32/108 (29%), Positives = 45/108 (41%), Gaps = 5/108 (4%)
Query: 88 SSPGRQMAPTFYTYPFNK-----VVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARI 142
+ P R ++T P V + V FKC G P+P W K+G P RI
Sbjct: 144 TKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRI 203
Query: 143 TVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVITRS 190
+ + +D V D G Y VENE G + +L+V+ RS
Sbjct: 204 GGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERS 251
Score = 41.1 bits (92), Expect = 0.003
Identities = 29/90 (32%), Positives = 41/90 (45%), Gaps = 15/90 (16%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEV--------------IRDCADFESSYDDGTARLKI 51
G VEF C+V +P P I+W + EV I A ++ D L +
Sbjct: 270 GSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTT-DKEMEVLHL 328
Query: 52 KQVTAEDEGTYTCEASNCLGKAKSNACLVV 81
+ V+ ED G YTC A N +G + +A L V
Sbjct: 329 RNVSFEDAGEYTCLAGNSIGLSHHSAWLTV 358
>AL590556-2|CAH71870.1| 4391|Homo sapiens heparan sulfate proteoglycan
2 (perlecan) protein.
Length = 4391
Score = 68.1 bits (159), Expect = 2e-11
Identities = 54/181 (29%), Positives = 81/181 (44%), Gaps = 24/181 (13%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G T C TG+P P I W +R ++ + T L I +V +D G Y C
Sbjct: 3226 GHTATLRCSATGSPAPTIHW----SKLRSPLPWQHRLEGDT--LIIPRVAQQDSGQYICN 3279
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A++ G A++ ++ H + SP P T P + V+ GE V +C G P
Sbjct: 3280 ATSPAGHAEAT---IILH---VESP-----PYATTVPEHASVQAGETVQLQCLAHGTPPL 3328
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
W + GS + R T + + +L + + ED G YR V N++G AEA A+L
Sbjct: 3329 TFQWSRVGSSLP--GRATARNE-----LLHFERAAPEDSGRYRCRVTNKVGSAEAFAQLL 3381
Query: 186 V 186
V
Sbjct: 3382 V 3382
Score = 67.7 bits (158), Expect = 3e-11
Identities = 55/185 (29%), Positives = 76/185 (41%), Gaps = 27/185 (14%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G VEFEC G+P P + W +R G ++I V D G Y C
Sbjct: 3503 GHAVEFECLALGDPKPQVTWSKVGGHLRP-----GIVQSGGV-VRIAHVELADAGQYRCT 3556
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A+N G +S+ L+V ++S P P G F C G P+P
Sbjct: 3557 ATNAAGTTQSHVLLLVQALPQISMPQEVRVPA------------GSAAVFPCIASGYPTP 3604
Query: 126 WASWDK-DGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
SW K DGS + P +R+ E +M + V +D G Y T N G+ +A A L
Sbjct: 3605 DISWSKLDGS-LPPDSRL---ENNMLM----LPSVRPQDAGTYVCTATNRQGKVKAFAHL 3656
Query: 185 EVITR 189
+V R
Sbjct: 3657 QVPER 3661
Score = 64.1 bits (149), Expect = 4e-10
Identities = 51/181 (28%), Positives = 70/181 (38%), Gaps = 12/181 (6%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G V EC G P RW + D A L+I D GTY C
Sbjct: 3127 GKAVTLECVSAGEPRSSARWTRISSTPAKLEQRTYGLMDSHAVLQISSAKPSDAGTYVCL 3186
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A N LG A+ ++V +PG AP VE G T +C+ G+P+P
Sbjct: 3187 AQNALGTAQKQVEVIV--DTGAMAPG---APQVQAEEAELTVEAGHTATLRCSATGSPAP 3241
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
W K S + R+ E + ++ I V+ +D G Y + G AEA+ L
Sbjct: 3242 TIHWSKLRSPLPWQHRL---EGDTLI----IPRVAQQDSGQYICNATSPAGHAEATIILH 3294
Query: 186 V 186
V
Sbjct: 3295 V 3295
Score = 62.1 bits (144), Expect = 1e-09
Identities = 52/199 (26%), Positives = 80/199 (40%), Gaps = 18/199 (9%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G EF C TG+P P + W ++ G RL + T D+ Y C
Sbjct: 1880 GQLAEFRCSATGSPTPTLEW---TGGPGGQLPAKAQIHGGILRLPAVEPT--DQAQYLCR 1934
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A + G+ + A V H P Q++P V G V C G PS
Sbjct: 1935 AHSSAGQQVARA---VLHVHGGGGPRVQVSPE------RTQVHAGRTVRLYCRAAGVPSA 1985
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
+W K+G + P AR E+ +I +L I ++ D G Y + G A+A ++
Sbjct: 1986 TITWRKEGGSLPPQAR---SERTDIATLL-IPAITTADAGFYLCVATSPAGTAQARIQVV 2041
Query: 186 VITRSGKFYGGLRAYSASP 204
V++ S ++ S+SP
Sbjct: 2042 VLSASDASPPPVKIESSSP 2060
Score = 61.7 bits (143), Expect = 2e-09
Identities = 51/181 (28%), Positives = 80/181 (44%), Gaps = 22/181 (12%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G +VEF C V + +RWF + S DG L+I+ + +GTY C+
Sbjct: 3414 GASVEFHCAVPSDRGTQLRWFKEGGQLPP----GHSVQDGV--LRIQNLDQSCQGTYICQ 3467
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A GKA+++A LV+ + L S + + T V G V F+C G+P P
Sbjct: 3468 AHGPWGKAQASAQLVI---QALPSVLINIRTSVQT------VVVGHAVEFECLALGDPKP 3518
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
+W K G + P + + ++RI ++ + D G YR T N G ++ L
Sbjct: 3519 QVTWSKVGGHLRPG----IVQSGGVVRIAHVE---LADAGQYRCTATNAAGTTQSHVLLL 3571
Query: 186 V 186
V
Sbjct: 3572 V 3572
Score = 57.2 bits (132), Expect = 4e-08
Identities = 52/191 (27%), Positives = 77/191 (40%), Gaps = 18/191 (9%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G TV C+ G P I W + A E + A L I +T D G Y C
Sbjct: 1970 GRTVRLYCRAAGVPSATITWRKEGGSLPPQARSERT---DIATLLIPAITTADAGFYLCV 2026
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A++ G A++ +VV S P ++ + + V EG+ + C V G+
Sbjct: 2027 ATSPAGTAQARIQVVVLSASDASPPPVKIESS------SPSVTEGQTLDLNCVVAGSAHA 2080
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
+W + G + P ++ L + +VS D G Y VEN G EAS +
Sbjct: 2081 QVTWYRRGGSLPPHTQVHGSR-------LRLPQVSPADSGEYVCRVENGSGPKEASITVS 2133
Query: 186 VI--TRSGKFY 194
V+ T SG Y
Sbjct: 2134 VLHGTHSGPSY 2144
Score = 55.6 bits (128), Expect = 1e-07
Identities = 48/187 (25%), Positives = 73/187 (39%), Gaps = 15/187 (8%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G T++ C V I W+ S + +RL+I QVT D G Y C
Sbjct: 2547 NGHTLDLNCLVASQAPHTITWYKRG------GSLPSRHQIVGSRLRIPQVTPADSGEYVC 2600
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
SN G +++ L+V SS ++P + V EG+ + C V P
Sbjct: 2601 HVSNGAGSRETS--LIVTIQGSGSSHVPSVSPPIRIESSSPTVVEGQTLDLNCVVARQPQ 2658
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
+W K G + PS T L + ++S+ D G Y N + EAS +
Sbjct: 2659 AIITWYKRGGSL-PSRHQTHGSH------LRLHQMSVADSGEYVCRANNNIDALEASIVI 2711
Query: 185 EVITRSG 191
V +G
Sbjct: 2712 SVSPSAG 2718
Score = 55.6 bits (128), Expect = 1e-07
Identities = 46/184 (25%), Positives = 78/184 (42%), Gaps = 16/184 (8%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+TV+ +C G P +W + A + L ++ ED G Y C
Sbjct: 3313 GETVQLQCLAHGTPPLTFQWSRVGSSLPGRATARNEL------LHFERAAPEDSGRYRCR 3366
Query: 66 ASNCLGKAKSNACLVVYH---TRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGN 122
+N +G A++ A L+V + +S PT P + G +V F CAV +
Sbjct: 3367 VTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQVTPQLETKSIGASVEFHCAVPSD 3426
Query: 123 PSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASA 182
W K+G + P + ++ ++RI +D+ S + G Y G+A+ASA
Sbjct: 3427 RGTQLRWFKEGGQLPPGHSV----QDGVLRIQNLDQ-SCQ--GTYICQAHGPWGKAQASA 3479
Query: 183 RLEV 186
+L +
Sbjct: 3480 QLVI 3483
Score = 54.4 bits (125), Expect = 3e-07
Identities = 43/184 (23%), Positives = 71/184 (38%), Gaps = 15/184 (8%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G+T++ C V G + W S + +RL++ V+ D G Y C
Sbjct: 2740 EGETLDLNCVVPGQAHAQVTWHKRG------GSLPSHHQTRGSRLRLHHVSPADSGEYVC 2793
Query: 65 EASNCLGKAKSNACLVVYHT--RRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGN 122
G +++ + + + + P AP P + V EG+ + KC V G
Sbjct: 2794 RVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPIRIEPSSSRVAEGQTLDLKCVVPGQ 2853
Query: 123 PSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASA 182
+W K G + AR V +L +++VS D G Y V G EAS
Sbjct: 2854 AHAQVTWHKRGGNL--PARHQVHGP-----LLRLNQVSPADSGEYSCQVTGSSGTLEASV 2906
Query: 183 RLEV 186
+ +
Sbjct: 2907 LVTI 2910
Score = 51.6 bits (118), Expect = 2e-06
Identities = 49/188 (26%), Positives = 74/188 (39%), Gaps = 17/188 (9%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G T++ C V P I W+ S + + L++ Q++ D G Y C
Sbjct: 2643 EGQTLDLNCVVARQPQAIITWYKRG------GSLPSRHQTHGSHLRLHQMSVADSGEYVC 2696
Query: 65 EASNCLGKAKSNACLVVYHTRRL-SSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
A+N + +++ + V + S+PG M + + V EGE + C V G
Sbjct: 2697 RANNNIDALEASIVISVSPSAGSPSAPGSSMPIRIESSSSH--VAEGETLDLNCVVPGQA 2754
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
+W K G + PS T + L + VS D G Y V G EAS
Sbjct: 2755 HAQVTWHKRGGSL-PSHHQTRGSR------LRLHHVSPADSGEYVCRVMGSSGPLEASV- 2806
Query: 184 LEVITRSG 191
L I SG
Sbjct: 2807 LVTIEASG 2814
Score = 50.8 bits (116), Expect = 4e-06
Identities = 44/186 (23%), Positives = 70/186 (37%), Gaps = 18/186 (9%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G T++ C V G+ + W+ + S RL++ QV+ D G Y C
Sbjct: 2064 EGQTLDLNCVVAGSAHAQVTWYRRGGSLPPHTQVHGS------RLRLPQVSPADSGEYVC 2117
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAP----TFYTYPFNKVVEEGENVTFKCAVK 120
N G +++ + V H S P P P + V EG+ + C V
Sbjct: 2118 RVENGSGPKEASITVSVLHGTH-SGPSYTPVPGSTRPIRIEPSSSHVAEGQTLDLNCVVP 2176
Query: 121 GNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEA 180
G +W K G + P+ T +L + +V+ D G Y V G EA
Sbjct: 2177 GQAHAQVTWHKRGGSL-PARHQTHGS------LLRLHQVTPADSGEYVCHVVGTSGPLEA 2229
Query: 181 SARLEV 186
S + +
Sbjct: 2230 SVLVTI 2235
Score = 46.4 bits (105), Expect = 8e-05
Identities = 26/81 (32%), Positives = 36/81 (44%), Gaps = 6/81 (7%)
Query: 49 LKIKQVTAEDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVE 108
L I+ V D GTY C SN + A L V + LS AP +P V+
Sbjct: 1825 LTIRNVQLSDAGTYVCTGSNMFAMDQGTATLHVQASGTLS------APVVSIHPPQLTVQ 1878
Query: 109 EGENVTFKCAVKGNPSPWASW 129
G+ F+C+ G+P+P W
Sbjct: 1879 PGQLAEFRCSATGSPTPTLEW 1899
Score = 46.4 bits (105), Expect = 8e-05
Identities = 38/183 (20%), Positives = 71/183 (38%), Gaps = 13/183 (7%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G T++ C V G + W+ + + ++L++ V+ D G Y C
Sbjct: 2938 EGQTLDLNCVVPGQAHAQVTWYKRG------GSLPARHQTHGSQLRLHLVSPADSGEYVC 2991
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
A++ G + + V SS R +P P + V++G++ +FKC + +
Sbjct: 2992 RAASGPGPEQEASFTVTVPPSEGSSY-RLRSPVISIDPPSSTVQQGQDASFKCLIHDGAA 3050
Query: 125 PWA-SWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
P + W + + I+ I+ I + G YR N G A++
Sbjct: 3051 PISLEWKTRNQELEDNVHISPNGS-----IITIVGTRPSNHGTYRCVASNAYGVAQSVVN 3105
Query: 184 LEV 186
L V
Sbjct: 3106 LSV 3108
Score = 46.0 bits (104), Expect = 1e-04
Identities = 26/129 (20%), Positives = 51/129 (39%), Gaps = 6/129 (4%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G T++ +C V G + W + + + L++ QV+ D G Y+C
Sbjct: 2840 EGQTLDLKCVVPGQAHAQVTWHKRG------GNLPARHQVHGPLLRLNQVSPADSGEYSC 2893
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
+ + G +++ + + + P +A Y + V EG+ + C V G
Sbjct: 2894 QVTGSSGTLEASVLVTIEPSSPGPIPAPGLAQPIYIEASSSHVTEGQTLDLNCVVPGQAH 2953
Query: 125 PWASWDKDG 133
+W K G
Sbjct: 2954 AQVTWYKRG 2962
Score = 45.2 bits (102), Expect = 2e-04
Identities = 31/129 (24%), Positives = 48/129 (37%), Gaps = 8/129 (6%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G T++ C V G + W+ + + +RL I Q + D G Y C
Sbjct: 2258 EGQTLDLSCVVAGQAHAQVTWYKRG------GSLPARHQVRGSRLYIFQASPADAGQYVC 2311
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
ASN + +A + L+ P P P + V EG+ + C V G
Sbjct: 2312 RASNGM-EASITVTVTGTQGANLAYPAGSTQP-IRIEPSSSQVAEGQTLDLNCVVPGQSH 2369
Query: 125 PWASWDKDG 133
+W K G
Sbjct: 2370 AQVTWHKRG 2378
Score = 44.4 bits (100), Expect = 3e-04
Identities = 42/140 (30%), Positives = 58/140 (41%), Gaps = 15/140 (10%)
Query: 58 DEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKV-VEEGENVTFK 116
+ GTY C ASN G A+S L V+ P PT P V V+ G+ VT +
Sbjct: 3085 NHGTYRCVASNAYGVAQSVVNLSVH------GP-----PTVSVLPEGPVWVKVGKAVTLE 3133
Query: 117 CAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG 176
C G P A W + S + T + +L+I D G Y +N LG
Sbjct: 3134 CVSAGEPRSSARWTRISSTPAKLEQRTYGLMDS-HAVLQISSAKPSDAGTYVCLAQNALG 3192
Query: 177 RAEASARLEVITRSGKFYGG 196
A+ ++EVI +G G
Sbjct: 3193 TAQ--KQVEVIVDTGAMAPG 3210
Score = 42.3 bits (95), Expect = 0.001
Identities = 24/66 (36%), Positives = 28/66 (42%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G TV F C G P P I W I + + G L I+ V D+G YTCE
Sbjct: 421 GQTVTFTCVAIGVPTPIINWRLNWGHIPSHPRVTVTSEGGRGTLIIRDVKESDQGAYTCE 480
Query: 66 ASNCLG 71
A N G
Sbjct: 481 AMNARG 486
Score = 39.9 bits (89), Expect = 0.007
Identities = 45/194 (23%), Positives = 69/194 (35%), Gaps = 16/194 (8%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G T++ C V G + W + + L++ Q + D G Y C
Sbjct: 2354 EGQTLDLNCVVPGQSHAQVTWHKRG------GSLPVRHQTHGSLLRLYQASPADSGEYVC 2407
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
A ++V S P + PT + V EG+ + C V G
Sbjct: 2408 RVLG--SSVPLEASVLVTIEPAGSVPALGVTPTVRIESSSSQVAEGQTLDLNCLVAGQAH 2465
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
+W K G + AR V +R+L +V+ D G Y V G EAS +
Sbjct: 2466 AQVTWHKRGGSL--PARHQVHGSR--LRLL---QVTPADSGEYVCRVVGSSGTQEASVLV 2518
Query: 185 EVITR-SGKFYGGL 197
+ R SG G+
Sbjct: 2519 TIQQRLSGSHSQGV 2532
Score = 39.1 bits (87), Expect = 0.012
Identities = 28/129 (21%), Positives = 45/129 (34%), Gaps = 11/129 (8%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G T++ C V G + W + + + L++ QVT D G Y C
Sbjct: 2165 EGQTLDLNCVVPGQAHAQVTWHKRG------GSLPARHQTHGSLLRLHQVTPADSGEYVC 2218
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
G +++ LV + P P + V EG+ + C V G
Sbjct: 2219 HVVGTSGPLEASV-LVTIEASVIPGP----IPPVRIESSSSTVAEGQTLDLSCVVAGQAH 2273
Query: 125 PWASWDKDG 133
+W K G
Sbjct: 2274 AQVTWYKRG 2282
Score = 35.5 bits (78), Expect = 0.15
Identities = 26/84 (30%), Positives = 33/84 (39%), Gaps = 2/84 (2%)
Query: 94 MAPTFYTYPFNKV-VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMR 152
M P T P + G+ VTF C G P+P +W + I R+TV E
Sbjct: 404 MPPQVVTPPRESIQASRGQTVTFTCVAIGVPTPIINWRLNWGHIPSHPRVTV-TSEGGRG 462
Query: 153 ILEIDEVSIEDVGIYRITVENELG 176
L I +V D G Y N G
Sbjct: 463 TLIIRDVKESDQGAYTCEAMNARG 486
Score = 33.1 bits (72), Expect = 0.78
Identities = 21/85 (24%), Positives = 33/85 (38%), Gaps = 5/85 (5%)
Query: 90 PGRQMAPTFY-TYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKE 148
P AP +P +V +G + + +C V G+P + W ++ PS +
Sbjct: 1670 PETNQAPLVVEVHPARSIVPQGGSHSLRCQVSGSPPHYFYWSREDGRPVPSGTQQRHQGS 1729
Query: 149 EIMRILEIDEVSIEDVGIYRITVEN 173
E L V D G+Y T N
Sbjct: 1730 E----LHFPSVQPSDAGVYICTCRN 1750
>AL590103-2|CAI12125.1| 4391|Homo sapiens heparan sulfate proteoglycan
2 (perlecan) protein.
Length = 4391
Score = 68.1 bits (159), Expect = 2e-11
Identities = 54/181 (29%), Positives = 81/181 (44%), Gaps = 24/181 (13%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G T C TG+P P I W +R ++ + T L I +V +D G Y C
Sbjct: 3226 GHTATLRCSATGSPAPTIHW----SKLRSPLPWQHRLEGDT--LIIPRVAQQDSGQYICN 3279
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A++ G A++ ++ H + SP P T P + V+ GE V +C G P
Sbjct: 3280 ATSPAGHAEAT---IILH---VESP-----PYATTVPEHASVQAGETVQLQCLAHGTPPL 3328
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
W + GS + R T + + +L + + ED G YR V N++G AEA A+L
Sbjct: 3329 TFQWSRVGSSLP--GRATARNE-----LLHFERAAPEDSGRYRCRVTNKVGSAEAFAQLL 3381
Query: 186 V 186
V
Sbjct: 3382 V 3382
Score = 67.7 bits (158), Expect = 3e-11
Identities = 55/185 (29%), Positives = 76/185 (41%), Gaps = 27/185 (14%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G VEFEC G+P P + W +R G ++I V D G Y C
Sbjct: 3503 GHAVEFECLALGDPKPQVTWSKVGGHLRP-----GIVQSGGV-VRIAHVELADAGQYRCT 3556
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A+N G +S+ L+V ++S P P G F C G P+P
Sbjct: 3557 ATNAAGTTQSHVLLLVQALPQISMPQEVRVPA------------GSAAVFPCIASGYPTP 3604
Query: 126 WASWDK-DGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
SW K DGS + P +R+ E +M + V +D G Y T N G+ +A A L
Sbjct: 3605 DISWSKLDGS-LPPDSRL---ENNMLM----LPSVRPQDAGTYVCTATNRQGKVKAFAHL 3656
Query: 185 EVITR 189
+V R
Sbjct: 3657 QVPER 3661
Score = 64.1 bits (149), Expect = 4e-10
Identities = 51/181 (28%), Positives = 70/181 (38%), Gaps = 12/181 (6%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G V EC G P RW + D A L+I D GTY C
Sbjct: 3127 GKAVTLECVSAGEPRSSARWTRISSTPAKLEQRTYGLMDSHAVLQISSAKPSDAGTYVCL 3186
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A N LG A+ ++V +PG AP VE G T +C+ G+P+P
Sbjct: 3187 AQNALGTAQKQVEVIV--DTGAMAPG---APQVQAEEAELTVEAGHTATLRCSATGSPAP 3241
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
W K S + R+ E + ++ I V+ +D G Y + G AEA+ L
Sbjct: 3242 TIHWSKLRSPLPWQHRL---EGDTLI----IPRVAQQDSGQYICNATSPAGHAEATIILH 3294
Query: 186 V 186
V
Sbjct: 3295 V 3295
Score = 62.1 bits (144), Expect = 1e-09
Identities = 52/199 (26%), Positives = 80/199 (40%), Gaps = 18/199 (9%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G EF C TG+P P + W ++ G RL + T D+ Y C
Sbjct: 1880 GQLAEFRCSATGSPTPTLEW---TGGPGGQLPAKAQIHGGILRLPAVEPT--DQAQYLCR 1934
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A + G+ + A V H P Q++P V G V C G PS
Sbjct: 1935 AHSSAGQQVARA---VLHVHGGGGPRVQVSPE------RTQVHAGRTVRLYCRAAGVPSA 1985
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
+W K+G + P AR E+ +I +L I ++ D G Y + G A+A ++
Sbjct: 1986 TITWRKEGGSLPPQAR---SERTDIATLL-IPAITTADAGFYLCVATSPAGTAQARIQVV 2041
Query: 186 VITRSGKFYGGLRAYSASP 204
V++ S ++ S+SP
Sbjct: 2042 VLSASDASPPPVKIESSSP 2060
Score = 61.7 bits (143), Expect = 2e-09
Identities = 51/181 (28%), Positives = 80/181 (44%), Gaps = 22/181 (12%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G +VEF C V + +RWF + S DG L+I+ + +GTY C+
Sbjct: 3414 GASVEFHCAVPSDRGTQLRWFKEGGQLPP----GHSVQDGV--LRIQNLDQSCQGTYICQ 3467
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A GKA+++A LV+ + L S + + T V G V F+C G+P P
Sbjct: 3468 AHGPWGKAQASAQLVI---QALPSVLINIRTSVQT------VVVGHAVEFECLALGDPKP 3518
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
+W K G + P + + ++RI ++ + D G YR T N G ++ L
Sbjct: 3519 QVTWSKVGGHLRPG----IVQSGGVVRIAHVE---LADAGQYRCTATNAAGTTQSHVLLL 3571
Query: 186 V 186
V
Sbjct: 3572 V 3572
Score = 57.2 bits (132), Expect = 4e-08
Identities = 52/191 (27%), Positives = 77/191 (40%), Gaps = 18/191 (9%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G TV C+ G P I W + A E + A L I +T D G Y C
Sbjct: 1970 GRTVRLYCRAAGVPSATITWRKEGGSLPPQARSERT---DIATLLIPAITTADAGFYLCV 2026
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A++ G A++ +VV S P ++ + + V EG+ + C V G+
Sbjct: 2027 ATSPAGTAQARIQVVVLSASDASPPPVKIESS------SPSVTEGQTLDLNCVVAGSAHA 2080
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
+W + G + P ++ L + +VS D G Y VEN G EAS +
Sbjct: 2081 QVTWYRRGGSLPPHTQVHGSR-------LRLPQVSPADSGEYVCRVENGSGPKEASITVS 2133
Query: 186 VI--TRSGKFY 194
V+ T SG Y
Sbjct: 2134 VLHGTHSGPSY 2144
Score = 55.6 bits (128), Expect = 1e-07
Identities = 48/187 (25%), Positives = 73/187 (39%), Gaps = 15/187 (8%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G T++ C V I W+ S + +RL+I QVT D G Y C
Sbjct: 2547 NGHTLDLNCLVASQAPHTITWYKRG------GSLPSRHQIVGSRLRIPQVTPADSGEYVC 2600
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
SN G +++ L+V SS ++P + V EG+ + C V P
Sbjct: 2601 HVSNGAGSRETS--LIVTIQGSGSSHVPSVSPPIRIESSSPTVVEGQTLDLNCVVARQPQ 2658
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
+W K G + PS T L + ++S+ D G Y N + EAS +
Sbjct: 2659 AIITWYKRGGSL-PSRHQTHGSH------LRLHQMSVADSGEYVCRANNNIDALEASIVI 2711
Query: 185 EVITRSG 191
V +G
Sbjct: 2712 SVSPSAG 2718
Score = 55.6 bits (128), Expect = 1e-07
Identities = 46/184 (25%), Positives = 78/184 (42%), Gaps = 16/184 (8%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+TV+ +C G P +W + A + L ++ ED G Y C
Sbjct: 3313 GETVQLQCLAHGTPPLTFQWSRVGSSLPGRATARNEL------LHFERAAPEDSGRYRCR 3366
Query: 66 ASNCLGKAKSNACLVVYH---TRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGN 122
+N +G A++ A L+V + +S PT P + G +V F CAV +
Sbjct: 3367 VTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQVTPQLETKSIGASVEFHCAVPSD 3426
Query: 123 PSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASA 182
W K+G + P + ++ ++RI +D+ S + G Y G+A+ASA
Sbjct: 3427 RGTQLRWFKEGGQLPPGHSV----QDGVLRIQNLDQ-SCQ--GTYICQAHGPWGKAQASA 3479
Query: 183 RLEV 186
+L +
Sbjct: 3480 QLVI 3483
Score = 54.4 bits (125), Expect = 3e-07
Identities = 43/184 (23%), Positives = 71/184 (38%), Gaps = 15/184 (8%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G+T++ C V G + W S + +RL++ V+ D G Y C
Sbjct: 2740 EGETLDLNCVVPGQAHAQVTWHKRG------GSLPSHHQTRGSRLRLHHVSPADSGEYVC 2793
Query: 65 EASNCLGKAKSNACLVVYHT--RRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGN 122
G +++ + + + + P AP P + V EG+ + KC V G
Sbjct: 2794 RVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPIRIEPSSSRVAEGQTLDLKCVVPGQ 2853
Query: 123 PSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASA 182
+W K G + AR V +L +++VS D G Y V G EAS
Sbjct: 2854 AHAQVTWHKRGGNL--PARHQVHGP-----LLRLNQVSPADSGEYSCQVTGSSGTLEASV 2906
Query: 183 RLEV 186
+ +
Sbjct: 2907 LVTI 2910
Score = 51.6 bits (118), Expect = 2e-06
Identities = 49/188 (26%), Positives = 74/188 (39%), Gaps = 17/188 (9%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G T++ C V P I W+ S + + L++ Q++ D G Y C
Sbjct: 2643 EGQTLDLNCVVARQPQAIITWYKRG------GSLPSRHQTHGSHLRLHQMSVADSGEYVC 2696
Query: 65 EASNCLGKAKSNACLVVYHTRRL-SSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
A+N + +++ + V + S+PG M + + V EGE + C V G
Sbjct: 2697 RANNNIDALEASIVISVSPSAGSPSAPGSSMPIRIESSSSH--VAEGETLDLNCVVPGQA 2754
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
+W K G + PS T + L + VS D G Y V G EAS
Sbjct: 2755 HAQVTWHKRGGSL-PSHHQTRGSR------LRLHHVSPADSGEYVCRVMGSSGPLEASV- 2806
Query: 184 LEVITRSG 191
L I SG
Sbjct: 2807 LVTIEASG 2814
Score = 50.8 bits (116), Expect = 4e-06
Identities = 44/186 (23%), Positives = 70/186 (37%), Gaps = 18/186 (9%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G T++ C V G+ + W+ + S RL++ QV+ D G Y C
Sbjct: 2064 EGQTLDLNCVVAGSAHAQVTWYRRGGSLPPHTQVHGS------RLRLPQVSPADSGEYVC 2117
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAP----TFYTYPFNKVVEEGENVTFKCAVK 120
N G +++ + V H S P P P + V EG+ + C V
Sbjct: 2118 RVENGSGPKEASITVSVLHGTH-SGPSYTPVPGSTRPIRIEPSSSHVAEGQTLDLNCVVP 2176
Query: 121 GNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEA 180
G +W K G + P+ T +L + +V+ D G Y V G EA
Sbjct: 2177 GQAHAQVTWHKRGGSL-PARHQTHGS------LLRLHQVTPADSGEYVCHVVGTSGPLEA 2229
Query: 181 SARLEV 186
S + +
Sbjct: 2230 SVLVTI 2235
Score = 46.4 bits (105), Expect = 8e-05
Identities = 26/81 (32%), Positives = 36/81 (44%), Gaps = 6/81 (7%)
Query: 49 LKIKQVTAEDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVE 108
L I+ V D GTY C SN + A L V + LS AP +P V+
Sbjct: 1825 LTIRNVQLSDAGTYVCTGSNMFAMDQGTATLHVQASGTLS------APVVSIHPPQLTVQ 1878
Query: 109 EGENVTFKCAVKGNPSPWASW 129
G+ F+C+ G+P+P W
Sbjct: 1879 PGQLAEFRCSATGSPTPTLEW 1899
Score = 46.4 bits (105), Expect = 8e-05
Identities = 38/183 (20%), Positives = 71/183 (38%), Gaps = 13/183 (7%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G T++ C V G + W+ + + ++L++ V+ D G Y C
Sbjct: 2938 EGQTLDLNCVVPGQAHAQVTWYKRG------GSLPARHQTHGSQLRLHLVSPADSGEYVC 2991
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
A++ G + + V SS R +P P + V++G++ +FKC + +
Sbjct: 2992 RAASGPGPEQEASFTVTVPPSEGSSY-RLRSPVISIDPPSSTVQQGQDASFKCLIHDGAA 3050
Query: 125 PWA-SWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
P + W + + I+ I+ I + G YR N G A++
Sbjct: 3051 PISLEWKTRNQELEDNVHISPNGS-----IITIVGTRPSNHGTYRCVASNAYGVAQSVVN 3105
Query: 184 LEV 186
L V
Sbjct: 3106 LSV 3108
Score = 46.0 bits (104), Expect = 1e-04
Identities = 26/129 (20%), Positives = 51/129 (39%), Gaps = 6/129 (4%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G T++ +C V G + W + + + L++ QV+ D G Y+C
Sbjct: 2840 EGQTLDLKCVVPGQAHAQVTWHKRG------GNLPARHQVHGPLLRLNQVSPADSGEYSC 2893
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
+ + G +++ + + + P +A Y + V EG+ + C V G
Sbjct: 2894 QVTGSSGTLEASVLVTIEPSSPGPIPAPGLAQPIYIEASSSHVTEGQTLDLNCVVPGQAH 2953
Query: 125 PWASWDKDG 133
+W K G
Sbjct: 2954 AQVTWYKRG 2962
Score = 45.2 bits (102), Expect = 2e-04
Identities = 31/129 (24%), Positives = 48/129 (37%), Gaps = 8/129 (6%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G T++ C V G + W+ + + +RL I Q + D G Y C
Sbjct: 2258 EGQTLDLSCVVAGQAHAQVTWYKRG------GSLPARHQVRGSRLYIFQASPADAGQYVC 2311
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
ASN + +A + L+ P P P + V EG+ + C V G
Sbjct: 2312 RASNGM-EASITVTVTGTQGANLAYPAGSTQP-IRIEPSSSQVAEGQTLDLNCVVPGQSH 2369
Query: 125 PWASWDKDG 133
+W K G
Sbjct: 2370 AQVTWHKRG 2378
Score = 44.4 bits (100), Expect = 3e-04
Identities = 42/140 (30%), Positives = 58/140 (41%), Gaps = 15/140 (10%)
Query: 58 DEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKV-VEEGENVTFK 116
+ GTY C ASN G A+S L V+ P PT P V V+ G+ VT +
Sbjct: 3085 NHGTYRCVASNAYGVAQSVVNLSVH------GP-----PTVSVLPEGPVWVKVGKAVTLE 3133
Query: 117 CAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG 176
C G P A W + S + T + +L+I D G Y +N LG
Sbjct: 3134 CVSAGEPRSSARWTRISSTPAKLEQRTYGLMDS-HAVLQISSAKPSDAGTYVCLAQNALG 3192
Query: 177 RAEASARLEVITRSGKFYGG 196
A+ ++EVI +G G
Sbjct: 3193 TAQ--KQVEVIVDTGAMAPG 3210
Score = 42.3 bits (95), Expect = 0.001
Identities = 24/66 (36%), Positives = 28/66 (42%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G TV F C G P P I W I + + G L I+ V D+G YTCE
Sbjct: 421 GQTVTFTCVAIGVPTPIINWRLNWGHIPSHPRVTVTSEGGRGTLIIRDVKESDQGAYTCE 480
Query: 66 ASNCLG 71
A N G
Sbjct: 481 AMNARG 486
Score = 39.9 bits (89), Expect = 0.007
Identities = 45/194 (23%), Positives = 69/194 (35%), Gaps = 16/194 (8%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G T++ C V G + W + + L++ Q + D G Y C
Sbjct: 2354 EGQTLDLNCVVPGQSHAQVTWHKRG------GSLPVRHQTHGSLLRLYQASPADSGEYVC 2407
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
A ++V S P + PT + V EG+ + C V G
Sbjct: 2408 RVLG--SSVPLEASVLVTIEPAGSVPALGVTPTVRIESSSSQVAEGQTLDLNCLVAGQAH 2465
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
+W K G + AR V +R+L +V+ D G Y V G EAS +
Sbjct: 2466 AQVTWHKRGGSL--PARHQVHGSR--LRLL---QVTPADSGEYVCRVVGSSGTQEASVLV 2518
Query: 185 EVITR-SGKFYGGL 197
+ R SG G+
Sbjct: 2519 TIQQRLSGSHSQGV 2532
Score = 39.1 bits (87), Expect = 0.012
Identities = 28/129 (21%), Positives = 45/129 (34%), Gaps = 11/129 (8%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G T++ C V G + W + + + L++ QVT D G Y C
Sbjct: 2165 EGQTLDLNCVVPGQAHAQVTWHKRG------GSLPARHQTHGSLLRLHQVTPADSGEYVC 2218
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
G +++ LV + P P + V EG+ + C V G
Sbjct: 2219 HVVGTSGPLEASV-LVTIEASVIPGP----IPPVRIESSSSTVAEGQTLDLSCVVAGQAH 2273
Query: 125 PWASWDKDG 133
+W K G
Sbjct: 2274 AQVTWYKRG 2282
Score = 35.5 bits (78), Expect = 0.15
Identities = 26/84 (30%), Positives = 33/84 (39%), Gaps = 2/84 (2%)
Query: 94 MAPTFYTYPFNKV-VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMR 152
M P T P + G+ VTF C G P+P +W + I R+TV E
Sbjct: 404 MPPQVVTPPRESIQASRGQTVTFTCVAIGVPTPIINWRLNWGHIPSHPRVTV-TSEGGRG 462
Query: 153 ILEIDEVSIEDVGIYRITVENELG 176
L I +V D G Y N G
Sbjct: 463 TLIIRDVKESDQGAYTCEAMNARG 486
Score = 33.1 bits (72), Expect = 0.78
Identities = 21/85 (24%), Positives = 33/85 (38%), Gaps = 5/85 (5%)
Query: 90 PGRQMAPTFY-TYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKE 148
P AP +P +V +G + + +C V G+P + W ++ PS +
Sbjct: 1670 PETNQAPLVVEVHPARSIVPQGGSHSLRCQVSGSPPHYFYWSREDGRPVPSGTQQRHQGS 1729
Query: 149 EIMRILEIDEVSIEDVGIYRITVEN 173
E L V D G+Y T N
Sbjct: 1730 E----LHFPSVQPSDAGVYICTCRN 1750
>AL445795-1|CAC18534.1| 4370|Homo sapiens heparan sulfate proteoglycan
perlecan protein.
Length = 4370
Score = 68.1 bits (159), Expect = 2e-11
Identities = 54/181 (29%), Positives = 81/181 (44%), Gaps = 24/181 (13%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G T C TG+P P I W +R ++ + T L I +V +D G Y C
Sbjct: 3205 GHTATLRCSATGSPAPTIHW----SKLRSPLPWQHRLEGDT--LIIPRVAQQDSGQYICN 3258
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A++ G A++ ++ H + SP P T P + V+ GE V +C G P
Sbjct: 3259 ATSPAGHAEAT---IILH---VESP-----PYATTVPEHASVQAGETVQLQCLAHGTPPL 3307
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
W + GS + R T + + +L + + ED G YR V N++G AEA A+L
Sbjct: 3308 TFQWSRVGSSLP--GRATARNE-----LLHFERAAPEDSGRYRCRVTNKVGSAEAFAQLL 3360
Query: 186 V 186
V
Sbjct: 3361 V 3361
Score = 67.7 bits (158), Expect = 3e-11
Identities = 55/185 (29%), Positives = 76/185 (41%), Gaps = 27/185 (14%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G VEFEC G+P P + W +R G ++I V D G Y C
Sbjct: 3482 GHAVEFECLALGDPKPQVTWSKVGGHLRP-----GIVQSGGV-VRIAHVELADAGQYRCT 3535
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A+N G +S+ L+V ++S P P G F C G P+P
Sbjct: 3536 ATNAAGTTQSHVLLLVQALPQISMPQEVRVPA------------GSAAVFPCIASGYPTP 3583
Query: 126 WASWDK-DGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
SW K DGS + P +R+ E +M + V +D G Y T N G+ +A A L
Sbjct: 3584 DISWSKLDGS-LPPDSRL---ENNMLM----LPSVRPQDAGTYVCTATNRQGKVKAFAHL 3635
Query: 185 EVITR 189
+V R
Sbjct: 3636 QVPER 3640
Score = 64.1 bits (149), Expect = 4e-10
Identities = 51/181 (28%), Positives = 70/181 (38%), Gaps = 12/181 (6%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G V EC G P RW + D A L+I D GTY C
Sbjct: 3106 GKAVTLECVSAGEPRSSARWTRISSTPAKLEQRTYGLMDSHAVLQISSAKPSDAGTYVCL 3165
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A N LG A+ ++V +PG AP VE G T +C+ G+P+P
Sbjct: 3166 AQNALGTAQKQVEVIV--DTGAMAPG---APQVQAEEAELTVEAGHTATLRCSATGSPAP 3220
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
W K S + R+ E + ++ I V+ +D G Y + G AEA+ L
Sbjct: 3221 TIHWSKLRSPLPWQHRL---EGDTLI----IPRVAQQDSGQYICNATSPAGHAEATIILH 3273
Query: 186 V 186
V
Sbjct: 3274 V 3274
Score = 62.1 bits (144), Expect = 1e-09
Identities = 52/199 (26%), Positives = 80/199 (40%), Gaps = 18/199 (9%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G EF C TG+P P + W ++ G RL + T D+ Y C
Sbjct: 1859 GQLAEFRCSATGSPTPTLEW---TGGPGGQLPAKAQIHGGILRLPAVEPT--DQAQYLCR 1913
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A + G+ + A V H P Q++P V G V C G PS
Sbjct: 1914 AHSSAGQQVARA---VLHVHGGGGPRVQVSPE------RTQVHAGRTVRLYCRAAGVPSA 1964
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
+W K+G + P AR E+ +I +L I ++ D G Y + G A+A ++
Sbjct: 1965 TITWRKEGGSLPPQAR---SERTDIATLL-IPAITTADAGFYLCVATSPAGTAQARIQVV 2020
Query: 186 VITRSGKFYGGLRAYSASP 204
V++ S ++ S+SP
Sbjct: 2021 VLSASDASPPPVKIESSSP 2039
Score = 61.7 bits (143), Expect = 2e-09
Identities = 51/181 (28%), Positives = 80/181 (44%), Gaps = 22/181 (12%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G +VEF C V + +RWF + S DG L+I+ + +GTY C+
Sbjct: 3393 GASVEFHCAVPSDRGTQLRWFKEGGQLPP----GHSVQDGV--LRIQNLDQSCQGTYICQ 3446
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A GKA+++A LV+ + L S + + T V G V F+C G+P P
Sbjct: 3447 AHGPWGKAQASAQLVI---QALPSVLINIRTSVQT------VVVGHAVEFECLALGDPKP 3497
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
+W K G + P + + ++RI ++ + D G YR T N G ++ L
Sbjct: 3498 QVTWSKVGGHLRPG----IVQSGGVVRIAHVE---LADAGQYRCTATNAAGTTQSHVLLL 3550
Query: 186 V 186
V
Sbjct: 3551 V 3551
Score = 57.2 bits (132), Expect = 4e-08
Identities = 52/191 (27%), Positives = 77/191 (40%), Gaps = 18/191 (9%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G TV C+ G P I W + A E + A L I +T D G Y C
Sbjct: 1949 GRTVRLYCRAAGVPSATITWRKEGGSLPPQARSERT---DIATLLIPAITTADAGFYLCV 2005
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A++ G A++ +VV S P ++ + + V EG+ + C V G+
Sbjct: 2006 ATSPAGTAQARIQVVVLSASDASPPPVKIESS------SPSVTEGQTLDLNCVVAGSAHA 2059
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
+W + G + P ++ L + +VS D G Y VEN G EAS +
Sbjct: 2060 QVTWYRRGGSLPPHTQVHGSR-------LRLPQVSPADSGEYVCRVENGSGPKEASITVS 2112
Query: 186 VI--TRSGKFY 194
V+ T SG Y
Sbjct: 2113 VLHGTHSGPSY 2123
Score = 55.6 bits (128), Expect = 1e-07
Identities = 48/187 (25%), Positives = 73/187 (39%), Gaps = 15/187 (8%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G T++ C V I W+ S + +RL+I QVT D G Y C
Sbjct: 2526 NGHTLDLNCLVASQAPHTITWYKRG------GSLPSRHQIVGSRLRIPQVTPADSGEYVC 2579
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
SN G +++ L+V SS ++P + V EG+ + C V P
Sbjct: 2580 HVSNGAGSRETS--LIVTIQGSGSSHVPSVSPPIRIESSSPTVVEGQTLDLNCVVARQPQ 2637
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
+W K G + PS T L + ++S+ D G Y N + EAS +
Sbjct: 2638 AIITWYKRGGSL-PSRHQTHGSH------LRLHQMSVADSGEYVCRANNNIDALEASIVI 2690
Query: 185 EVITRSG 191
V +G
Sbjct: 2691 SVSPSAG 2697
Score = 55.6 bits (128), Expect = 1e-07
Identities = 46/184 (25%), Positives = 78/184 (42%), Gaps = 16/184 (8%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+TV+ +C G P +W + A + L ++ ED G Y C
Sbjct: 3292 GETVQLQCLAHGTPPLTFQWSRVGSSLPGRATARNEL------LHFERAAPEDSGRYRCR 3345
Query: 66 ASNCLGKAKSNACLVVYH---TRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGN 122
+N +G A++ A L+V + +S PT P + G +V F CAV +
Sbjct: 3346 VTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQVTPQLETKSIGASVEFHCAVPSD 3405
Query: 123 PSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASA 182
W K+G + P + ++ ++RI +D+ S + G Y G+A+ASA
Sbjct: 3406 RGTQLRWFKEGGQLPPGHSV----QDGVLRIQNLDQ-SCQ--GTYICQAHGPWGKAQASA 3458
Query: 183 RLEV 186
+L +
Sbjct: 3459 QLVI 3462
Score = 54.4 bits (125), Expect = 3e-07
Identities = 43/184 (23%), Positives = 71/184 (38%), Gaps = 15/184 (8%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G+T++ C V G + W S + +RL++ V+ D G Y C
Sbjct: 2719 EGETLDLNCVVPGQAHAQVTWHKRG------GSLPSHHQTRGSRLRLHHVSPADSGEYVC 2772
Query: 65 EASNCLGKAKSNACLVVYHT--RRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGN 122
G +++ + + + + P AP P + V EG+ + KC V G
Sbjct: 2773 RVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPIRIEPSSSRVAEGQTLDLKCVVPGQ 2832
Query: 123 PSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASA 182
+W K G + AR V +L +++VS D G Y V G EAS
Sbjct: 2833 AHAQVTWHKRGGNL--PARHQVHGP-----LLRLNQVSPADSGEYSCQVTGSSGTLEASV 2885
Query: 183 RLEV 186
+ +
Sbjct: 2886 LVTI 2889
Score = 51.6 bits (118), Expect = 2e-06
Identities = 49/188 (26%), Positives = 74/188 (39%), Gaps = 17/188 (9%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G T++ C V P I W+ S + + L++ Q++ D G Y C
Sbjct: 2622 EGQTLDLNCVVARQPQAIITWYKRG------GSLPSRHQTHGSHLRLHQMSVADSGEYVC 2675
Query: 65 EASNCLGKAKSNACLVVYHTRRL-SSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
A+N + +++ + V + S+PG M + + V EGE + C V G
Sbjct: 2676 RANNNIDALEASIVISVSPSAGSPSAPGSSMPIRIESSSSH--VAEGETLDLNCVVPGQA 2733
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
+W K G + PS T + L + VS D G Y V G EAS
Sbjct: 2734 HAQVTWHKRGGSL-PSHHQTRGSR------LRLHHVSPADSGEYVCRVMGSSGPLEASV- 2785
Query: 184 LEVITRSG 191
L I SG
Sbjct: 2786 LVTIEASG 2793
Score = 50.8 bits (116), Expect = 4e-06
Identities = 44/186 (23%), Positives = 70/186 (37%), Gaps = 18/186 (9%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G T++ C V G+ + W+ + S RL++ QV+ D G Y C
Sbjct: 2043 EGQTLDLNCVVAGSAHAQVTWYRRGGSLPPHTQVHGS------RLRLPQVSPADSGEYVC 2096
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAP----TFYTYPFNKVVEEGENVTFKCAVK 120
N G +++ + V H S P P P + V EG+ + C V
Sbjct: 2097 RVENGSGPKEASITVSVLHGTH-SGPSYTPVPGSTRPIRIEPSSSHVAEGQTLDLNCVVP 2155
Query: 121 GNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEA 180
G +W K G + P+ T +L + +V+ D G Y V G EA
Sbjct: 2156 GQAHAQVTWHKRGGSL-PARHQTHGS------LLRLHQVTPADSGEYVCHVVGTSGPLEA 2208
Query: 181 SARLEV 186
S + +
Sbjct: 2209 SVLVTI 2214
Score = 46.4 bits (105), Expect = 8e-05
Identities = 26/81 (32%), Positives = 36/81 (44%), Gaps = 6/81 (7%)
Query: 49 LKIKQVTAEDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVE 108
L I+ V D GTY C SN + A L V + LS AP +P V+
Sbjct: 1804 LTIRNVQLSDAGTYVCTGSNMFAMDQGTATLHVQASGTLS------APVVSIHPPQLTVQ 1857
Query: 109 EGENVTFKCAVKGNPSPWASW 129
G+ F+C+ G+P+P W
Sbjct: 1858 PGQLAEFRCSATGSPTPTLEW 1878
Score = 46.4 bits (105), Expect = 8e-05
Identities = 38/183 (20%), Positives = 71/183 (38%), Gaps = 13/183 (7%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G T++ C V G + W+ + + ++L++ V+ D G Y C
Sbjct: 2917 EGQTLDLNCVVPGQAHAQVTWYKRG------GSLPARHQTHGSQLRLHLVSPADSGEYVC 2970
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
A++ G + + V SS R +P P + V++G++ +FKC + +
Sbjct: 2971 RAASGPGPEQEASFTVTVPPSEGSSY-RLRSPVISIDPPSSTVQQGQDASFKCLIHDGAA 3029
Query: 125 PWA-SWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
P + W + + I+ I+ I + G YR N G A++
Sbjct: 3030 PISLEWKTRNQELEDNVHISPNGS-----IITIVGTRPSNHGTYRCVASNAYGVAQSVVN 3084
Query: 184 LEV 186
L V
Sbjct: 3085 LSV 3087
Score = 46.0 bits (104), Expect = 1e-04
Identities = 26/129 (20%), Positives = 51/129 (39%), Gaps = 6/129 (4%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G T++ +C V G + W + + + L++ QV+ D G Y+C
Sbjct: 2819 EGQTLDLKCVVPGQAHAQVTWHKRG------GNLPARHQVHGPLLRLNQVSPADSGEYSC 2872
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
+ + G +++ + + + P +A Y + V EG+ + C V G
Sbjct: 2873 QVTGSSGTLEASVLVTIEPSSPGPIPAPGLAQPIYIEASSSHVTEGQTLDLNCVVPGQAH 2932
Query: 125 PWASWDKDG 133
+W K G
Sbjct: 2933 AQVTWYKRG 2941
Score = 45.2 bits (102), Expect = 2e-04
Identities = 31/129 (24%), Positives = 48/129 (37%), Gaps = 8/129 (6%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G T++ C V G + W+ + + +RL I Q + D G Y C
Sbjct: 2237 EGQTLDLSCVVAGQAHAQVTWYKRG------GSLPARHQVRGSRLYIFQASPADAGQYVC 2290
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
ASN + +A + L+ P P P + V EG+ + C V G
Sbjct: 2291 RASNGM-EASITVTVTGTQGANLAYPAGSTQP-IRIEPSSSQVAEGQTLDLNCVVPGQSH 2348
Query: 125 PWASWDKDG 133
+W K G
Sbjct: 2349 AQVTWHKRG 2357
Score = 44.4 bits (100), Expect = 3e-04
Identities = 42/140 (30%), Positives = 58/140 (41%), Gaps = 15/140 (10%)
Query: 58 DEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKV-VEEGENVTFK 116
+ GTY C ASN G A+S L V+ P PT P V V+ G+ VT +
Sbjct: 3064 NHGTYRCVASNAYGVAQSVVNLSVH------GP-----PTVSVLPEGPVWVKVGKAVTLE 3112
Query: 117 CAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG 176
C G P A W + S + T + +L+I D G Y +N LG
Sbjct: 3113 CVSAGEPRSSARWTRISSTPAKLEQRTYGLMDS-HAVLQISSAKPSDAGTYVCLAQNALG 3171
Query: 177 RAEASARLEVITRSGKFYGG 196
A+ ++EVI +G G
Sbjct: 3172 TAQ--KQVEVIVDTGAMAPG 3189
Score = 42.3 bits (95), Expect = 0.001
Identities = 24/66 (36%), Positives = 28/66 (42%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G TV F C G P P I W I + + G L I+ V D+G YTCE
Sbjct: 400 GQTVTFTCVAIGVPTPIINWRLNWGHIPSHPRVTVTSEGGRGTLIIRDVKESDQGAYTCE 459
Query: 66 ASNCLG 71
A N G
Sbjct: 460 AMNARG 465
Score = 39.9 bits (89), Expect = 0.007
Identities = 45/194 (23%), Positives = 69/194 (35%), Gaps = 16/194 (8%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G T++ C V G + W + + L++ Q + D G Y C
Sbjct: 2333 EGQTLDLNCVVPGQSHAQVTWHKRG------GSLPVRHQTHGSLLRLYQASPADSGEYVC 2386
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
A ++V S P + PT + V EG+ + C V G
Sbjct: 2387 RVLG--SSVPLEASVLVTIEPAGSVPALGVTPTVRIESSSSQVAEGQTLDLNCLVAGQAH 2444
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
+W K G + AR V +R+L +V+ D G Y V G EAS +
Sbjct: 2445 AQVTWHKRGGSL--PARHQVHGSR--LRLL---QVTPADSGEYVCRVVGSSGTQEASVLV 2497
Query: 185 EVITR-SGKFYGGL 197
+ R SG G+
Sbjct: 2498 TIQQRLSGSHSQGV 2511
Score = 39.1 bits (87), Expect = 0.012
Identities = 28/129 (21%), Positives = 45/129 (34%), Gaps = 11/129 (8%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G T++ C V G + W + + + L++ QVT D G Y C
Sbjct: 2144 EGQTLDLNCVVPGQAHAQVTWHKRG------GSLPARHQTHGSLLRLHQVTPADSGEYVC 2197
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
G +++ LV + P P + V EG+ + C V G
Sbjct: 2198 HVVGTSGPLEASV-LVTIEASVIPGP----IPPVRIESSSSTVAEGQTLDLSCVVAGQAH 2252
Query: 125 PWASWDKDG 133
+W K G
Sbjct: 2253 AQVTWYKRG 2261
Score = 35.5 bits (78), Expect = 0.15
Identities = 26/84 (30%), Positives = 33/84 (39%), Gaps = 2/84 (2%)
Query: 94 MAPTFYTYPFNKV-VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMR 152
M P T P + G+ VTF C G P+P +W + I R+TV E
Sbjct: 383 MPPQVVTPPRESIQASRGQTVTFTCVAIGVPTPIINWRLNWGHIPSHPRVTV-TSEGGRG 441
Query: 153 ILEIDEVSIEDVGIYRITVENELG 176
L I +V D G Y N G
Sbjct: 442 TLIIRDVKESDQGAYTCEAMNARG 465
Score = 33.1 bits (72), Expect = 0.78
Identities = 21/85 (24%), Positives = 33/85 (38%), Gaps = 5/85 (5%)
Query: 90 PGRQMAPTFY-TYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKE 148
P AP +P +V +G + + +C V G+P + W ++ PS +
Sbjct: 1649 PETNQAPLVVEVHPARSIVPQGGSHSLRCQVSGSPPHYFYWSREDGRPVPSGTQQRHQGS 1708
Query: 149 EIMRILEIDEVSIEDVGIYRITVEN 173
E L V D G+Y T N
Sbjct: 1709 E----LHFPSVQPSDAGVYICTCRN 1729
>AB208919-1|BAD92156.1| 814|Homo sapiens fibroblast growth factor
receptor 1 isoform 1 precursor variant protein.
Length = 814
Score = 68.1 bits (159), Expect = 2e-11
Identities = 59/197 (29%), Positives = 82/197 (41%), Gaps = 27/197 (13%)
Query: 8 TVEFECQVTGNPDPDIRWFHYAEVIRD---CADFESSYDDGTARLKIKQVTAEDEGTYTC 64
TV+F+C +G P+P +RW + + ++ Y T + + V D+G YTC
Sbjct: 167 TVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRY--ATWSIIMDSVVPSDKGNYTC 224
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
N G L V SP R + P NK V G NV F C V +P
Sbjct: 225 IVENEYGSINHTYQLDVVER----SPHRPILQA--GLPANKTVALGSNVEFMCKVYSDPQ 278
Query: 125 PWASWDK----DGSIITP----------SARITVKEKEEIMRILEIDEVSIEDVGIYRIT 170
P W K +GS I P +A + +KE M +L + VS ED G Y
Sbjct: 279 PHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKE--MEVLHLRNVSFEDAGEYTCL 336
Query: 171 VENELGRAEASARLEVI 187
N +G + SA L V+
Sbjct: 337 AGNSIGLSHHSAWLTVL 353
Score = 48.8 bits (111), Expect = 1e-05
Identities = 32/108 (29%), Positives = 45/108 (41%), Gaps = 5/108 (4%)
Query: 88 SSPGRQMAPTFYTYPFNK-----VVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARI 142
+ P R ++T P V + V FKC G P+P W K+G P RI
Sbjct: 138 TKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRI 197
Query: 143 TVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVITRS 190
+ + +D V D G Y VENE G + +L+V+ RS
Sbjct: 198 GGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERS 245
Score = 41.1 bits (92), Expect = 0.003
Identities = 29/90 (32%), Positives = 41/90 (45%), Gaps = 15/90 (16%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEV--------------IRDCADFESSYDDGTARLKI 51
G VEF C+V +P P I+W + EV I A ++ D L +
Sbjct: 264 GSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTT-DKEMEVLHL 322
Query: 52 KQVTAEDEGTYTCEASNCLGKAKSNACLVV 81
+ V+ ED G YTC A N +G + +A L V
Sbjct: 323 RNVSFEDAGEYTCLAGNSIGLSHHSAWLTV 352
>AB209851-1|BAD93088.1| 2331|Homo sapiens Basement membrane-specific
heparan sulfate proteoglycan core protein precursor
protein.
Length = 2331
Score = 67.7 bits (158), Expect = 3e-11
Identities = 54/181 (29%), Positives = 81/181 (44%), Gaps = 24/181 (13%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G T C TG+P P I W +R ++ + T L I +V +D G Y C
Sbjct: 1166 GHTATLRCSATGSPAPTIHW----SKLRSPLPWQYRLEGDT--LIIPRVAQQDSGQYICN 1219
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A++ G A++ ++ H + SP P T P + V+ GE V +C G P
Sbjct: 1220 ATSPAGHAEAT---IILH---VESP-----PYATTVPEHASVQAGETVQLQCLAHGTPPL 1268
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
W + GS + R T + + +L + + ED G YR V N++G AEA A+L
Sbjct: 1269 TFQWSRVGSSLP--GRATARNE-----LLHFERAAPEDSGRYRCRVTNKVGSAEAFAQLL 1321
Query: 186 V 186
V
Sbjct: 1322 V 1322
Score = 67.7 bits (158), Expect = 3e-11
Identities = 55/185 (29%), Positives = 76/185 (41%), Gaps = 27/185 (14%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G VEFEC G+P P + W +R G ++I V D G Y C
Sbjct: 1443 GHAVEFECLALGDPKPQVTWSKVGGHLRP-----GIVQSGGV-VRIAHVELADAGQYRCT 1496
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A+N G +S+ L+V ++S P P G F C G P+P
Sbjct: 1497 ATNAAGTTQSHVLLLVQALPQISMPQEVRVPA------------GSAAVFPCIASGYPTP 1544
Query: 126 WASWDK-DGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
SW K DGS + P +R+ E +M + V +D G Y T N G+ +A A L
Sbjct: 1545 DISWSKLDGS-LPPDSRL---ENNMLM----LPSVRPQDAGTYVCTATNRQGKVKAFAHL 1596
Query: 185 EVITR 189
+V R
Sbjct: 1597 QVPER 1601
Score = 64.1 bits (149), Expect = 4e-10
Identities = 51/181 (28%), Positives = 70/181 (38%), Gaps = 12/181 (6%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G V EC G P RW + D A L+I D GTY C
Sbjct: 1067 GKAVTLECVSAGEPRSSARWTRISSTPAKLEQRTYGLMDSHAVLQISSAKPSDAGTYVCL 1126
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A N LG A+ ++V +PG AP VE G T +C+ G+P+P
Sbjct: 1127 AQNALGTAQKQVEVIV--DTGAMAPG---APQVQAEEAELTVEAGHTATLRCSATGSPAP 1181
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
W K S + R+ E + ++ I V+ +D G Y + G AEA+ L
Sbjct: 1182 TIHWSKLRSPLPWQYRL---EGDTLI----IPRVAQQDSGQYICNATSPAGHAEATIILH 1234
Query: 186 V 186
V
Sbjct: 1235 V 1235
Score = 61.7 bits (143), Expect = 2e-09
Identities = 51/181 (28%), Positives = 80/181 (44%), Gaps = 22/181 (12%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G +VEF C V + +RWF + S DG L+I+ + +GTY C+
Sbjct: 1354 GASVEFHCAVPSDRGTQLRWFKEGGQLPP----GHSVQDGV--LRIQNLDQSCQGTYICQ 1407
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A GKA+++A LV+ + L S + + T V G V F+C G+P P
Sbjct: 1408 AHGPWGKAQASAQLVI---QALPSVLINIRTSVQT------VVVGHAVEFECLALGDPKP 1458
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
+W K G + P + + ++RI ++ + D G YR T N G ++ L
Sbjct: 1459 QVTWSKVGGHLRPG----IVQSGGVVRIAHVE---LADAGQYRCTATNAAGTTQSHVLLL 1511
Query: 186 V 186
V
Sbjct: 1512 V 1512
Score = 55.6 bits (128), Expect = 1e-07
Identities = 48/187 (25%), Positives = 73/187 (39%), Gaps = 15/187 (8%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G T++ C V I W+ S + +RL+I QVT D G Y C
Sbjct: 487 NGHTLDLNCLVASQAPHTITWYKRG------GSLPSRHQIVGSRLRIPQVTPADSGEYVC 540
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
SN G +++ L+V SS ++P + V EG+ + C V P
Sbjct: 541 HVSNGAGSRETS--LIVTIQGSGSSHVPSVSPPIRIESSSPTVVEGQTLDLNCVVARQPQ 598
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
+W K G + PS T L + ++S+ D G Y N + EAS +
Sbjct: 599 AIITWYKRGGSL-PSRHQTHGSH------LRLHQMSVADSGEYVCRANNNIDALEASIVI 651
Query: 185 EVITRSG 191
V +G
Sbjct: 652 SVSPSAG 658
Score = 55.6 bits (128), Expect = 1e-07
Identities = 46/184 (25%), Positives = 78/184 (42%), Gaps = 16/184 (8%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+TV+ +C G P +W + A + L ++ ED G Y C
Sbjct: 1253 GETVQLQCLAHGTPPLTFQWSRVGSSLPGRATARNEL------LHFERAAPEDSGRYRCR 1306
Query: 66 ASNCLGKAKSNACLVVYH---TRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGN 122
+N +G A++ A L+V + +S PT P + G +V F CAV +
Sbjct: 1307 VTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQVTPQLETKSIGASVEFHCAVPSD 1366
Query: 123 PSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASA 182
W K+G + P + ++ ++RI +D+ S + G Y G+A+ASA
Sbjct: 1367 RGTQLRWFKEGGQLPPGHSV----QDGVLRIQNLDQ-SCQ--GTYICQAHGPWGKAQASA 1419
Query: 183 RLEV 186
+L +
Sbjct: 1420 QLVI 1423
Score = 54.4 bits (125), Expect = 3e-07
Identities = 43/184 (23%), Positives = 71/184 (38%), Gaps = 15/184 (8%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G+T++ C V G + W S + +RL++ V+ D G Y C
Sbjct: 680 EGETLDLNCVVPGQAHAQVTWHKRG------GSLPSHHQTRGSRLRLHHVSPADSGEYVC 733
Query: 65 EASNCLGKAKSNACLVVYHT--RRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGN 122
G +++ + + + + P AP P + V EG+ + KC V G
Sbjct: 734 RVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPIRIEPSSSRVAEGQTLDLKCVVPGQ 793
Query: 123 PSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASA 182
+W K G + AR V +L +++VS D G Y V G EAS
Sbjct: 794 AHAQVTWHKRGGNL--PARHQVHGP-----LLRLNQVSPADSGEYSCQVTGSSGTLEASV 846
Query: 183 RLEV 186
+ +
Sbjct: 847 LVTI 850
Score = 51.6 bits (118), Expect = 2e-06
Identities = 49/188 (26%), Positives = 74/188 (39%), Gaps = 17/188 (9%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G T++ C V P I W+ S + + L++ Q++ D G Y C
Sbjct: 583 EGQTLDLNCVVARQPQAIITWYKRG------GSLPSRHQTHGSHLRLHQMSVADSGEYVC 636
Query: 65 EASNCLGKAKSNACLVVYHTRRL-SSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
A+N + +++ + V + S+PG M + + V EGE + C V G
Sbjct: 637 RANNNIDALEASIVISVSPSAGSPSAPGSSMPIRIESSSSH--VAEGETLDLNCVVPGQA 694
Query: 124 SPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
+W K G + PS T + L + VS D G Y V G EAS
Sbjct: 695 HAQVTWHKRGGSL-PSHHQTRGSR------LRLHHVSPADSGEYVCRVMGSSGPLEASV- 746
Query: 184 LEVITRSG 191
L I SG
Sbjct: 747 LVTIEASG 754
Score = 50.8 bits (116), Expect = 4e-06
Identities = 44/186 (23%), Positives = 70/186 (37%), Gaps = 18/186 (9%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G T++ C V G+ + W+ + S RL++ QV+ D G Y C
Sbjct: 4 EGQTLDLNCVVAGSAHAQVTWYRRGGSLPPHTQVHGS------RLRLPQVSPADSGEYVC 57
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAP----TFYTYPFNKVVEEGENVTFKCAVK 120
N G +++ + V H S P P P + V EG+ + C V
Sbjct: 58 RVENGSGPKEASITVSVLHGTH-SGPSYTPVPGSTRPIRIEPSSSHVAEGQTLDLNCVVP 116
Query: 121 GNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEA 180
G +W K G + P+ T +L + +V+ D G Y V G EA
Sbjct: 117 GQAHAQVTWHKRGGSL-PARHQTHGS------LLRLHQVTPADSGEYVCHVVGTSGPLEA 169
Query: 181 SARLEV 186
S + +
Sbjct: 170 SVLVTI 175
Score = 46.4 bits (105), Expect = 8e-05
Identities = 38/183 (20%), Positives = 71/183 (38%), Gaps = 13/183 (7%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G T++ C V G + W+ + + ++L++ V+ D G Y C
Sbjct: 878 EGQTLDLNCVVPGQAHAQVTWYKRG------GSLPARHQTHGSQLRLHLVSPADSGEYVC 931
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
A++ G + + V SS R +P P + V++G++ +FKC + +
Sbjct: 932 RAASGPGPEQEASFTVTVPPSEGSSY-RLRSPVISIDPPSSTVQQGQDASFKCLIHDGAA 990
Query: 125 PWA-SWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASAR 183
P + W + + I+ I+ I + G YR N G A++
Sbjct: 991 PISLEWKTRNQELEDNVHISPNGS-----IITIVGTRPSNHGTYRCVASNAYGVAQSVVN 1045
Query: 184 LEV 186
L V
Sbjct: 1046 LSV 1048
Score = 46.0 bits (104), Expect = 1e-04
Identities = 26/129 (20%), Positives = 51/129 (39%), Gaps = 6/129 (4%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G T++ +C V G + W + + + L++ QV+ D G Y+C
Sbjct: 780 EGQTLDLKCVVPGQAHAQVTWHKRG------GNLPARHQVHGPLLRLNQVSPADSGEYSC 833
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
+ + G +++ + + + P +A Y + V EG+ + C V G
Sbjct: 834 QVTGSSGTLEASVLVTIEPSSPGPIPAPGLAQPIYIEASSSHVTEGQTLDLNCVVPGQAH 893
Query: 125 PWASWDKDG 133
+W K G
Sbjct: 894 AQVTWYKRG 902
Score = 45.2 bits (102), Expect = 2e-04
Identities = 31/129 (24%), Positives = 48/129 (37%), Gaps = 8/129 (6%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G T++ C V G + W+ + + +RL I Q + D G Y C
Sbjct: 198 EGQTLDLSCVVAGQAHAQVTWYKRG------GSLPARHQVRGSRLYIFQASPADAGQYVC 251
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
ASN + +A + L+ P P P + V EG+ + C V G
Sbjct: 252 RASNGM-EASITVTVTGTQGANLAYPAGSTQP-IRIEPSSSQVAEGQTLDLNCVVPGQSH 309
Query: 125 PWASWDKDG 133
+W K G
Sbjct: 310 AQVTWHKRG 318
Score = 44.4 bits (100), Expect = 3e-04
Identities = 42/140 (30%), Positives = 58/140 (41%), Gaps = 15/140 (10%)
Query: 58 DEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKV-VEEGENVTFK 116
+ GTY C ASN G A+S L V+ P PT P V V+ G+ VT +
Sbjct: 1025 NHGTYRCVASNAYGVAQSVVNLSVH------GP-----PTVSVLPEGPVWVKVGKAVTLE 1073
Query: 117 CAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG 176
C G P A W + S + T + +L+I D G Y +N LG
Sbjct: 1074 CVSAGEPRSSARWTRISSTPAKLEQRTYGLMDS-HAVLQISSAKPSDAGTYVCLAQNALG 1132
Query: 177 RAEASARLEVITRSGKFYGG 196
A+ ++EVI +G G
Sbjct: 1133 TAQ--KQVEVIVDTGAMAPG 1150
Score = 39.9 bits (89), Expect = 0.007
Identities = 45/194 (23%), Positives = 69/194 (35%), Gaps = 16/194 (8%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G T++ C V G + W + + L++ Q + D G Y C
Sbjct: 294 EGQTLDLNCVVPGQSHAQVTWHKRG------GSLPVRHQTHGSLLRLYQASPADSGEYVC 347
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
A ++V S P + PT + V EG+ + C V G
Sbjct: 348 RVLG--SSVPLEASVLVTIEPAGSVPALGVTPTVRIESSSSQVAEGQTLDLNCLVAGQAH 405
Query: 125 PWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
+W K G + AR V +R+L +V+ D G Y V G EAS +
Sbjct: 406 AQVTWHKRGGSL--PARHQVHGSR--LRLL---QVTPADSGEYVCRVVGSSGTQEASVLV 458
Query: 185 EVITR-SGKFYGGL 197
+ R SG G+
Sbjct: 459 TIQQRLSGSHSQGV 472
Score = 39.1 bits (87), Expect = 0.012
Identities = 28/129 (21%), Positives = 45/129 (34%), Gaps = 11/129 (8%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G T++ C V G + W + + + L++ QVT D G Y C
Sbjct: 105 EGQTLDLNCVVPGQAHAQVTWHKRG------GSLPARHQTHGSLLRLHQVTPADSGEYVC 158
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
G +++ LV + P P + V EG+ + C V G
Sbjct: 159 HVVGTSGPLEASV-LVTIEASVIPGP----IPPVRIESSSSTVAEGQTLDLSCVVAGQAH 213
Query: 125 PWASWDKDG 133
+W K G
Sbjct: 214 AQVTWYKRG 222
Score = 37.9 bits (84), Expect = 0.027
Identities = 27/90 (30%), Positives = 39/90 (43%), Gaps = 9/90 (10%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
V EG+ + C V G+ +W + G + P ++ L + +VS D G
Sbjct: 2 VTEGQTLDLNCVVAGSAHAQVTWYRRGGSLPPHTQVHGSR-------LRLPQVSPADSGE 54
Query: 167 YRITVENELGRAEASARLEVI--TRSGKFY 194
Y VEN G EAS + V+ T SG Y
Sbjct: 55 YVCRVENGSGPKEASITVSVLHGTHSGPSY 84
>BC045734-1|AAH45734.1| 442|Homo sapiens IGSF10 protein protein.
Length = 442
Score = 67.3 bits (157), Expect = 4e-11
Identities = 53/190 (27%), Positives = 81/190 (42%), Gaps = 21/190 (11%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSY---DDGTARLKIKQVTAEDEGTY 62
G+++ C G P P+I+W + + D Y D+GT L IK+ TA D G Y
Sbjct: 266 GESLSLHCVSDGIPKPNIKWTMPSGYVVDRPQINGKYILHDNGT--LVIKEATAYDRGNY 323
Query: 63 TCEASNCLGKAKSN--ACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVK 120
C+A N +G +V Y R + P R + V G C
Sbjct: 324 ICKAQNSVGHTLITVPVMIVAYPPRITNRPPRSI-----------VTRTGAAFQLHCVAL 372
Query: 121 GNPSPWASWD-KDGSIITPSA--RITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGR 177
G P P +W+ D S+++ ++ R E+ + L I D GIY+ T +N LG
Sbjct: 373 GVPKPEITWEMPDHSLLSTASKERTHGSEQLHLQGTLVIQNPQTSDSGIYKCTAKNPLGS 432
Query: 178 AEASARLEVI 187
A+ ++VI
Sbjct: 433 DYAATYIQVI 442
Score = 51.6 bits (118), Expect = 2e-06
Identities = 46/181 (25%), Positives = 72/181 (39%), Gaps = 16/181 (8%)
Query: 11 FECQVTGNPDPDIRWFHYAEVIRDCADFESS---YDDGTARLKIKQVTAEDEGTYTCEAS 67
F+C+ G P P++ W + + S + +GT L+I+ V D + C A
Sbjct: 78 FDCRAEGTPSPEVMWIMPDNIFLTAPYYGSRITVHKNGT--LEIRNVRLSDSADFICVAR 135
Query: 68 NCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNK--VVEEGENVTFKCAVKGNPSP 125
N G++ L V R PTF PFN+ V + G++ C+V GNP P
Sbjct: 136 NEGGESVLVVQLEVLEMLR--------RPTFRN-PFNEKIVAQLGKSTALNCSVDGNPPP 186
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
W + + + I + + ED G YR N++G E LE
Sbjct: 187 EIIWILPNGTRFSNGPQSYQYLIASNGSFIISKTTREDAGKYRCAARNKVGYIEKLVILE 246
Query: 186 V 186
+
Sbjct: 247 I 247
Score = 43.6 bits (98), Expect = 6e-04
Identities = 45/175 (25%), Positives = 63/175 (36%), Gaps = 17/175 (9%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYD---DGTARLKIKQVTAEDEGTY 62
G + C V GNP P+I W R ++ SY I + T ED G Y
Sbjct: 171 GKSTALNCSVDGNPPPEIIWI-LPNGTR-FSNGPQSYQYLIASNGSFIISKTTREDAGKY 228
Query: 63 TCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTY-PFNKVVEEGENVTFKCAVKG 121
C A N +G + L + G++ P TY P GE+++ C G
Sbjct: 229 RCAARNKVGYIEKLVILEI---------GQK--PVILTYAPGTVKGISGESLSLHCVSDG 277
Query: 122 NPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG 176
P P W + +I K L I E + D G Y +N +G
Sbjct: 278 IPKPNIKWTMPSGYVVDRPQINGKYILHDNGTLVIKEATAYDRGNYICKAQNSVG 332
Score = 31.9 bits (69), Expect = 1.8
Identities = 41/148 (27%), Positives = 57/148 (38%), Gaps = 23/148 (15%)
Query: 49 LKIKQVTAEDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVE 108
L I +V D G Y C A N G +Y +S P + YT N+ V
Sbjct: 17 LTINKVKLLDSGEYVCVARNPSGDDTK-----MYKLDVVSKP--PLINGLYT---NRTVI 66
Query: 109 EGENVT-----FKCAVKGNPSPWASWDKDGSIITPS----ARITVKEKEEIMRILEIDEV 159
+ V F C +G PSP W +I + +RITV + LEI V
Sbjct: 67 KATAVRHSKKHFDCRAEGTPSPEVMWIMPDNIFLTAPYYGSRITVHKNGT----LEIRNV 122
Query: 160 SIEDVGIYRITVENELGRAEASARLEVI 187
+ D + NE G + +LEV+
Sbjct: 123 RLSDSADFICVARNEGGESVLVVQLEVL 150
>BC031063-1|AAH31063.1| 602|Homo sapiens IGSF10 protein protein.
Length = 602
Score = 67.3 bits (157), Expect = 4e-11
Identities = 53/190 (27%), Positives = 81/190 (42%), Gaps = 21/190 (11%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSY---DDGTARLKIKQVTAEDEGTY 62
G+++ C G P P+I+W + + D Y D+GT L IK+ TA D G Y
Sbjct: 426 GESLSLHCVSDGIPKPNIKWTMPSGYVVDRPQINGKYILHDNGT--LVIKEATAYDRGNY 483
Query: 63 TCEASNCLGKAKSN--ACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVK 120
C+A N +G +V Y R + P R + V G C
Sbjct: 484 ICKAQNSVGHTLITVPVMIVAYPPRITNRPPRSI-----------VTRTGAAFQLHCVAL 532
Query: 121 GNPSPWASWD-KDGSIITPSA--RITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGR 177
G P P +W+ D S+++ ++ R E+ + L I D GIY+ T +N LG
Sbjct: 533 GVPKPEITWEMPDHSLLSTASKERTHGSEQLHLQGTLVIQNPQTSDSGIYKCTAKNPLGS 592
Query: 178 AEASARLEVI 187
A+ ++VI
Sbjct: 593 DYAATYIQVI 602
Score = 51.6 bits (118), Expect = 2e-06
Identities = 46/181 (25%), Positives = 72/181 (39%), Gaps = 16/181 (8%)
Query: 11 FECQVTGNPDPDIRWFHYAEVIRDCADFESS---YDDGTARLKIKQVTAEDEGTYTCEAS 67
F+C+ G P P++ W + + S + +GT L+I+ V D + C A
Sbjct: 238 FDCRAEGTPSPEVMWIMPDNIFLTAPYYGSRITVHKNGT--LEIRNVRLSDSADFICVAR 295
Query: 68 NCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNK--VVEEGENVTFKCAVKGNPSP 125
N G++ L V R PTF PFN+ V + G++ C+V GNP P
Sbjct: 296 NEGGESVLVVQLEVLEMLR--------RPTFRN-PFNEKIVAQLGKSTALNCSVDGNPPP 346
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
W + + + I + + ED G YR N++G E LE
Sbjct: 347 EIIWILPNGTRFSNGPQSYQYLIASNGSFIISKTTREDAGKYRCAARNKVGYIEKLVILE 406
Query: 186 V 186
+
Sbjct: 407 I 407
Score = 50.4 bits (115), Expect = 5e-06
Identities = 52/189 (27%), Positives = 76/189 (40%), Gaps = 20/189 (10%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYA-EVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
GDT +C+VTG+P P I W + ++I D + + +G+ L I +V D G Y C
Sbjct: 135 GDTAVLDCEVTGDPKPKIFWLLPSNDMISFSIDRYTFHANGS--LTINKVKLLDSGEYVC 192
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYP--FNKVVEEGENVTFKCAVKGN 122
A N G +Y +S P + YT F C +G
Sbjct: 193 VARNPSGDDTK-----MYKLDVVSKP--PLINGLYTSRTVIKATAVRHSKKHFDCRAEGT 245
Query: 123 PSPWASWDKDGSIITPS----ARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRA 178
PSP W +I + +RITV + LEI V + D + NE G +
Sbjct: 246 PSPEVMWIMPDNIFLTAPYYGSRITVHKNGT----LEIRNVRLSDSADFICVARNEGGES 301
Query: 179 EASARLEVI 187
+LEV+
Sbjct: 302 VLVVQLEVL 310
Score = 48.4 bits (110), Expect = 2e-05
Identities = 51/197 (25%), Positives = 81/197 (41%), Gaps = 29/197 (14%)
Query: 6 GDTVEFECQVTGNPDPDIRW-FHYAEVIRDCADFESS---------YDDGTARLKIKQVT 55
G + +C+ +G+P P+I W +I + + S +++GT L +V
Sbjct: 32 GKDFQVDCKASGSPVPEISWSLPDGTMINNAMQADDSGHRTRRYTLFNNGT--LYFNKVG 89
Query: 56 AEDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPG-RQMAPTFYTYPFNKVVEEGENVT 114
+EG YTC A N LGK + L V ++P RQ T NK ++ G+
Sbjct: 90 VAEEGDYTCYAQNTLGKDEMKVHLTVI----TAAPRIRQSNKT------NKRIKAGDTAV 139
Query: 115 FKCAVKGNPSPWASW--DKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVE 172
C V G+P P W + I R T L I++V + D G Y
Sbjct: 140 LDCEVTGDPKPKIFWLLPSNDMISFSIDRYTFHANGS----LTINKVKLLDSGEYVCVAR 195
Query: 173 NELGRAEASARLEVITR 189
N G +L+V+++
Sbjct: 196 NPSGDDTKMYKLDVVSK 212
Score = 43.6 bits (98), Expect = 6e-04
Identities = 45/175 (25%), Positives = 63/175 (36%), Gaps = 17/175 (9%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYD---DGTARLKIKQVTAEDEGTY 62
G + C V GNP P+I W R ++ SY I + T ED G Y
Sbjct: 331 GKSTALNCSVDGNPPPEIIWI-LPNGTR-FSNGPQSYQYLIASNGSFIISKTTREDAGKY 388
Query: 63 TCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTY-PFNKVVEEGENVTFKCAVKG 121
C A N +G + L + G++ P TY P GE+++ C G
Sbjct: 389 RCAARNKVGYIEKLVILEI---------GQK--PVILTYAPGTVKGISGESLSLHCVSDG 437
Query: 122 NPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG 176
P P W + +I K L I E + D G Y +N +G
Sbjct: 438 IPKPNIKWTMPSGYVVDRPQINGKYILHDNGTLVIKEATAYDRGNYICKAQNSVG 492
Score = 35.1 bits (77), Expect = 0.19
Identities = 27/93 (29%), Positives = 39/93 (41%), Gaps = 7/93 (7%)
Query: 103 FNKVVEEGENVTFKCAVKGNPSPWASWD-KDGSIIT------PSARITVKEKEEIMRILE 155
F K V G++ C G+P P SW DG++I S T + L
Sbjct: 25 FRKQVLHGKDFQVDCKASGSPVPEISWSLPDGTMINNAMQADDSGHRTRRYTLFNNGTLY 84
Query: 156 IDEVSIEDVGIYRITVENELGRAEASARLEVIT 188
++V + + G Y +N LG+ E L VIT
Sbjct: 85 FNKVGVAEEGDYTCYAQNTLGKDEMKVHLTVIT 117
>AY273815-1|AAQ16156.1| 2623|Homo sapiens bone specific CMF608
protein.
Length = 2623
Score = 67.3 bits (157), Expect = 4e-11
Identities = 53/190 (27%), Positives = 81/190 (42%), Gaps = 21/190 (11%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSY---DDGTARLKIKQVTAEDEGTY 62
G+++ C G P P+I+W + + D Y D+GT L IK+ TA D G Y
Sbjct: 2447 GESLSLHCVSDGIPKPNIKWTMPSGYVVDRPQINGKYILHDNGT--LVIKEATAYDRGNY 2504
Query: 63 TCEASNCLGKAKSN--ACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVK 120
C+A N +G +V Y R + P R + V G C
Sbjct: 2505 ICKAQNSVGHTLITVPVMIVAYPPRITNRPPRSI-----------VTRTGAAFQLHCVAL 2553
Query: 121 GNPSPWASWD-KDGSIITPSA--RITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGR 177
G P P +W+ D S+++ ++ R E+ + L I D GIY+ T +N LG
Sbjct: 2554 GVPKPEITWEMPDHSLLSTASKERTHGSEQLHLQGTLVIQNPQTSDSGIYKCTAKNPLGS 2613
Query: 178 AEASARLEVI 187
A+ ++VI
Sbjct: 2614 DYAATYIQVI 2623
Score = 57.6 bits (133), Expect = 3e-08
Identities = 54/194 (27%), Positives = 78/194 (40%), Gaps = 22/194 (11%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRD----CADFESSYDDGTARLKIKQVTAEDEGT 61
GD + C TG P P I W ++ + D + Y +G+ L I VT +D G
Sbjct: 1956 GDKLLLNCSATGEPKPQIMWRLPSKAVVDQQHRVGSWIHVYPNGS--LFIGSVTEKDSGV 2013
Query: 62 YTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKG 121
Y C A N +G L++ H P A + F K V G++ C G
Sbjct: 2014 YLCVARNKMGDD-----LILMHVSLRLKP----AKIDHKQYFRKQVLHGKDFQVDCKASG 2064
Query: 122 NPSPWASWD-KDGSIIT------PSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENE 174
+P P SW DG++I S T + L ++V + + G Y +N
Sbjct: 2065 SPVPEISWSLPDGTMINNAMQADDSGHRTRRYTLFNNGTLYFNKVGVAEEGDYTCYAQNT 2124
Query: 175 LGRAEASARLEVIT 188
LG+ E L VIT
Sbjct: 2125 LGKDEMKVHLTVIT 2138
Score = 56.0 bits (129), Expect = 1e-07
Identities = 47/180 (26%), Positives = 77/180 (42%), Gaps = 16/180 (8%)
Query: 13 CQVTGNPDPDIRWFHYAEVIRDCADFESS----YDDGTARLKIKQVTAEDEGTYTCEASN 68
C+ GNP P I W + ++S +GT L I++V +D G Y C ASN
Sbjct: 1670 CEAVGNPLPTIHWTRVPSGLDLSKRKQNSRVQVLPNGT--LSIQRVEIQDRGQYLCSASN 1727
Query: 69 CLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWAS 128
G + L V +S P R + V G V KC +G PSP +
Sbjct: 1728 LFGTDHLHVTLSV-----VSYPPRILERRTKEI----TVHSGSTVELKCRAEGRPSPTVT 1778
Query: 129 WD-KDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVI 187
W + ++++ S++ + + + L + +SI D G Y+ N G+ +++VI
Sbjct: 1779 WILANQTVVSESSQGSRQAVVTVDGTLVLHNLSIYDRGFYKCVASNPGGQDSLLVKIQVI 1838
Score = 51.6 bits (118), Expect = 2e-06
Identities = 46/181 (25%), Positives = 72/181 (39%), Gaps = 16/181 (8%)
Query: 11 FECQVTGNPDPDIRWFHYAEVIRDCADFESS---YDDGTARLKIKQVTAEDEGTYTCEAS 67
F+C+ G P P++ W + + S + +GT L+I+ V D + C A
Sbjct: 2259 FDCRAEGTPSPEVMWIMPDNIFLTAPYYGSRITVHKNGT--LEIRNVRLSDSADFICVAR 2316
Query: 68 NCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNK--VVEEGENVTFKCAVKGNPSP 125
N G++ L V R PTF PFN+ V + G++ C+V GNP P
Sbjct: 2317 NEGGESVLVVQLEVLEMLR--------RPTFRN-PFNEKIVAQLGKSTALNCSVDGNPPP 2367
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
W + + + I + + ED G YR N++G E LE
Sbjct: 2368 EIIWILPNGTRFSNGPQSYQYLIASNGSFIISKTTREDAGKYRCAARNKVGYIEKLVILE 2427
Query: 186 V 186
+
Sbjct: 2428 I 2428
Score = 51.2 bits (117), Expect = 3e-06
Identities = 55/192 (28%), Positives = 81/192 (42%), Gaps = 26/192 (13%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYA-EVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
GDT +C+VTG+P P I W + ++I D + + +G+ L I +V D G Y C
Sbjct: 2156 GDTAVLDCEVTGDPKPKIFWLLPSNDMISFSIDRYTFHANGS--LTINKVKLLDSGEYVC 2213
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVT-----FKCAV 119
A N G +Y +S P + YT N+ V + V F C
Sbjct: 2214 VARNPSGDDTK-----MYKLDVVSKP--PLINGLYT---NRTVIKATAVRHSKKHFDCRA 2263
Query: 120 KGNPSPWASWDKDGSIITPS----ARITVKEKEEIMRILEIDEVSIEDVGIYRITVENEL 175
+G PSP W +I + +RITV + LEI V + D + NE
Sbjct: 2264 EGTPSPEVMWIMPDNIFLTAPYYGSRITVHKNGT----LEIRNVRLSDSADFICVARNEG 2319
Query: 176 GRAEASARLEVI 187
G + +LEV+
Sbjct: 2320 GESVLVVQLEVL 2331
Score = 48.4 bits (110), Expect = 2e-05
Identities = 51/197 (25%), Positives = 81/197 (41%), Gaps = 29/197 (14%)
Query: 6 GDTVEFECQVTGNPDPDIRW-FHYAEVIRDCADFESS---------YDDGTARLKIKQVT 55
G + +C+ +G+P P+I W +I + + S +++GT L +V
Sbjct: 2053 GKDFQVDCKASGSPVPEISWSLPDGTMINNAMQADDSGHRTRRYTLFNNGT--LYFNKVG 2110
Query: 56 AEDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPG-RQMAPTFYTYPFNKVVEEGENVT 114
+EG YTC A N LGK + L V ++P RQ T NK ++ G+
Sbjct: 2111 VAEEGDYTCYAQNTLGKDEMKVHLTVI----TAAPRIRQSNKT------NKRIKAGDTAV 2160
Query: 115 FKCAVKGNPSPWASW--DKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVE 172
C V G+P P W + I R T L I++V + D G Y
Sbjct: 2161 LDCEVTGDPKPKIFWLLPSNDMISFSIDRYTFHANGS----LTINKVKLLDSGEYVCVAR 2216
Query: 173 NELGRAEASARLEVITR 189
N G +L+V+++
Sbjct: 2217 NPSGDDTKMYKLDVVSK 2233
Score = 48.0 bits (109), Expect = 3e-05
Identities = 41/176 (23%), Positives = 71/176 (40%), Gaps = 14/176 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESS----YDDGTARLKIKQVTAEDEGT 61
G++++ C G P P + W F +S + +GT L I+ + + D GT
Sbjct: 1857 GESLKLPCTAKGTPQPSVYWVLSDGTEVKPLQFTNSKLFLFSNGT--LYIRNLASSDRGT 1914
Query: 62 YTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKG 121
Y C A++ G + L + R++SP + A T V G+ + C+ G
Sbjct: 1915 YECIATSSTGSERRVVMLTM--EERVTSPRIEAASQKRT-----EVNFGDKLLLNCSATG 1967
Query: 122 NPSPWASWD-KDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG 176
P P W +++ R+ L I V+ +D G+Y N++G
Sbjct: 1968 EPKPQIMWRLPSKAVVDQQHRVGSWIHVYPNGSLFIGSVTEKDSGVYLCVARNKMG 2023
Score = 43.6 bits (98), Expect = 6e-04
Identities = 45/175 (25%), Positives = 63/175 (36%), Gaps = 17/175 (9%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYD---DGTARLKIKQVTAEDEGTY 62
G + C V GNP P+I W R ++ SY I + T ED G Y
Sbjct: 2352 GKSTALNCSVDGNPPPEIIWI-LPNGTR-FSNGPQSYQYLIASNGSFIISKTTREDAGKY 2409
Query: 63 TCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTY-PFNKVVEEGENVTFKCAVKG 121
C A N +G + L + G++ P TY P GE+++ C G
Sbjct: 2410 RCAARNKVGYIEKLVILEI---------GQK--PVILTYAPGTVKGISGESLSLHCVSDG 2458
Query: 122 NPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG 176
P P W + +I K L I E + D G Y +N +G
Sbjct: 2459 IPKPNIKWTMPSGYVVDRPQINGKYILHDNGTLVIKEATAYDRGNYICKAQNSVG 2513
Score = 41.9 bits (94), Expect = 0.002
Identities = 24/67 (35%), Positives = 36/67 (53%), Gaps = 3/67 (4%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAE-VIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
G+T++ C TG PD I W V+ + + ++GT L+I QVT +D+G Y C
Sbjct: 588 GETLDLPCHSTGIPDASISWVIPGNNVLYQSSRDKKVLNNGT--LRILQVTPKDQGYYRC 645
Query: 65 EASNCLG 71
A+N G
Sbjct: 646 VAANPSG 652
Score = 40.7 bits (91), Expect = 0.004
Identities = 38/139 (27%), Positives = 58/139 (41%), Gaps = 18/139 (12%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYD----DGTARLKIKQVTAEDEGT 61
G TVE +C+ G P P + W + + + S DGT L + ++ D G
Sbjct: 1760 GSTVELKCRAEGRPSPTVTWILANQTVVSESSQGSRQAVVTVDGT--LVLHNLSIYDRGF 1817
Query: 62 YTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEE-GENVTFKCAVK 120
Y C ASN G+ ++ LV +++P P +V GE++ C K
Sbjct: 1818 YKCVASNPGGQ---DSLLVKIQV--IAAP-----PVILEQRRQVIVGTWGESLKLPCTAK 1867
Query: 121 GNPSPWASWD-KDGSIITP 138
G P P W DG+ + P
Sbjct: 1868 GTPQPSVYWVLSDGTEVKP 1886
Score = 37.5 bits (83), Expect = 0.036
Identities = 42/176 (23%), Positives = 70/176 (39%), Gaps = 18/176 (10%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESS----YDDGTARLKIKQVTAEDEGT 61
G TV C G+P P + W A+ + A + S D + +L+++ + D G
Sbjct: 490 GGTVGLNCPGQGDPTPHVDWL-LADGSKVRAPYVSEDGRILIDKSGKLELQMADSFDTGV 548
Query: 62 YTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKG 121
Y C +SN +A ++ Y + + + + V GE + C G
Sbjct: 549 YHCISSN-----YDDADILTYRITVV----EPLVEAYQENGIHHTVFIGETLDLPCHSTG 599
Query: 122 NPSPWASWDKDG-SIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG 176
P SW G +++ S+R +RIL +V+ +D G YR N G
Sbjct: 600 IPDASISWVIPGNNVLYQSSRDKKVLNNGTLRIL---QVTPKDQGYYRCVAANPSG 652
>AK098838-1|BAC05429.1| 399|Homo sapiens protein ( Homo sapiens
cDNA FLJ25972 fis, clone TST05664. ).
Length = 399
Score = 67.3 bits (157), Expect = 4e-11
Identities = 53/190 (27%), Positives = 81/190 (42%), Gaps = 21/190 (11%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSY---DDGTARLKIKQVTAEDEGTY 62
G+++ C G P P+I+W + + D Y D+GT L IK+ TA D G Y
Sbjct: 223 GESLSLHCVSDGIPKPNIKWTMPSGYVVDRPQINGKYILHDNGT--LVIKEATAYDRGNY 280
Query: 63 TCEASNCLGKAKSN--ACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVK 120
C+A N +G +V Y R + P R + V G C
Sbjct: 281 ICKAQNSVGHTLITVPVMIVAYPPRITNRPPRSI-----------VTRTGAAFQLHCVAL 329
Query: 121 GNPSPWASWD-KDGSIITPSA--RITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGR 177
G P P +W+ D S+++ ++ R E+ + L I D GIY+ T +N LG
Sbjct: 330 GVPKPEITWEMPDHSLLSTASKERTHGSEQLHLQGTLVIQNPQTSDSGIYKCTAKNPLGS 389
Query: 178 AEASARLEVI 187
A+ ++VI
Sbjct: 390 DYAATYIQVI 399
Score = 51.6 bits (118), Expect = 2e-06
Identities = 46/181 (25%), Positives = 72/181 (39%), Gaps = 16/181 (8%)
Query: 11 FECQVTGNPDPDIRWFHYAEVIRDCADFESS---YDDGTARLKIKQVTAEDEGTYTCEAS 67
F+C+ G P P++ W + + S + +GT L+I+ V D + C A
Sbjct: 35 FDCRAEGTPSPEVMWIMPDNIFLTAPYYGSRITVHKNGT--LEIRNVRLSDSADFICVAR 92
Query: 68 NCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNK--VVEEGENVTFKCAVKGNPSP 125
N G++ L V R PTF PFN+ V + G++ C+V GNP P
Sbjct: 93 NEGGESVLVVQLEVLEMLR--------RPTFRN-PFNEKIVAQLGKSTALNCSVDGNPPP 143
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
W + + + I + + ED G YR N++G E LE
Sbjct: 144 EIIWILPNGTRFSNGPQSYQYLIASNGSFIISKTTREDAGKYRCAARNKVGYIEKLVILE 203
Query: 186 V 186
+
Sbjct: 204 I 204
Score = 43.6 bits (98), Expect = 6e-04
Identities = 45/175 (25%), Positives = 63/175 (36%), Gaps = 17/175 (9%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYD---DGTARLKIKQVTAEDEGTY 62
G + C V GNP P+I W R ++ SY I + T ED G Y
Sbjct: 128 GKSTALNCSVDGNPPPEIIWI-LPNGTR-FSNGPQSYQYLIASNGSFIISKTTREDAGKY 185
Query: 63 TCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTY-PFNKVVEEGENVTFKCAVKG 121
C A N +G + L + G++ P TY P GE+++ C G
Sbjct: 186 RCAARNKVGYIEKLVILEI---------GQK--PVILTYAPGTVKGISGESLSLHCVSDG 234
Query: 122 NPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG 176
P P W + +I K L I E + D G Y +N +G
Sbjct: 235 IPKPNIKWTMPSGYVVDRPQINGKYILHDNGTLVIKEATAYDRGNYICKAQNSVG 289
Score = 30.7 bits (66), Expect = 4.2
Identities = 23/77 (29%), Positives = 33/77 (42%), Gaps = 8/77 (10%)
Query: 115 FKCAVKGNPSPWASWDKDGSIITPS----ARITVKEKEEIMRILEIDEVSIEDVGIYRIT 170
F C +G PSP W +I + +RITV + LEI V + D +
Sbjct: 35 FDCRAEGTPSPEVMWIMPDNIFLTAPYYGSRITVHKNGT----LEIRNVRLSDSADFICV 90
Query: 171 VENELGRAEASARLEVI 187
NE G + +LEV+
Sbjct: 91 ARNEGGESVLVVQLEVL 107
>AK093583-1|BAC04201.1| 329|Homo sapiens protein ( Homo sapiens
cDNA FLJ36264 fis, clone THYMU2002815, weakly similar to
AXONIN-1 PRECURSOR. ).
Length = 329
Score = 67.3 bits (157), Expect = 4e-11
Identities = 48/182 (26%), Positives = 75/182 (41%), Gaps = 19/182 (10%)
Query: 7 DTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEA 66
+ V C+ +G P P I W E + + G +L+I + ED G Y C A
Sbjct: 94 EEVLLPCEASGIPRPTITW--QKEGLNVATGVSTQVLPG-GQLRIAHASPEDAGNYLCIA 150
Query: 67 SNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPW 126
N G A LVV Q+ P + EG + C +G+P P
Sbjct: 151 KNSAGSAMGKTRLVV-----------QVPPVIENGLPDLSTTEGSHAFLPCKARGSPEPN 199
Query: 127 ASWDKDGSIIT-PSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
+WDKDG ++ + T++ E++ + + +D G Y T EN +GRA L
Sbjct: 200 ITWDKDGQPVSGAEGKFTIQPSGELL----VKNLEGQDAGTYTCTAENAVGRARRRVHLT 255
Query: 186 VI 187
++
Sbjct: 256 IL 257
Score = 60.9 bits (141), Expect = 3e-09
Identities = 33/133 (24%), Positives = 60/133 (45%), Gaps = 13/133 (9%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G C+ G+P+P+I W + + + G L +K + +D GTYTC
Sbjct: 182 EGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPSG--ELLVKNLEGQDAGTYTC 239
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
A N +G+A+ L + + P F T P ++ + G+ + +CA +G+P+
Sbjct: 240 TAENAVGRARRRVHLTIL-----------VLPVFTTLPGDRSLRLGDRLWLRCAARGSPT 288
Query: 125 PWASWDKDGSIIT 137
P W + +T
Sbjct: 289 PRIGWTVNDRPVT 301
Score = 48.0 bits (109), Expect = 3e-05
Identities = 50/179 (27%), Positives = 65/179 (36%), Gaps = 19/179 (10%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYD-DGTARLKIKQVTAEDEGTYTCEAS 67
V C TG P P + W ++ S Y + L+I Q G YTC A
Sbjct: 5 VVLTCHSTGIPAPTVSW---SKAGAQLGARGSGYRVSPSGALEIGQALPIHAGRYTCSAR 61
Query: 68 NCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWA 127
N G A + L V +SP + P+ + V E E V C G P P
Sbjct: 62 NSAGVAHKHVFLTVQ-----ASPVVKPLPSVV-----RAVAE-EEVLLPCEASGIPRPTI 110
Query: 128 SWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEV 186
+W K+G + V + L I S ED G Y +N G A RL V
Sbjct: 111 TWQKEGLNVATGVSTQVLPGGQ----LRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVV 165
>AK093069-1|BAC04042.1| 650|Homo sapiens protein ( Homo sapiens
cDNA FLJ35750 fis, clone TESTI2004539, weakly similar to
Homo sapiens adlican mRNA. ).
Length = 650
Score = 67.3 bits (157), Expect = 4e-11
Identities = 53/190 (27%), Positives = 81/190 (42%), Gaps = 21/190 (11%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSY---DDGTARLKIKQVTAEDEGTY 62
G+++ C G P P+I+W + + D Y D+GT L IK+ TA D G Y
Sbjct: 474 GESLSLHCVSDGIPKPNIKWTMPSGYVVDRPQINGKYILHDNGT--LVIKEATAYDRGNY 531
Query: 63 TCEASNCLGKAKSN--ACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVK 120
C+A N +G +V Y R + P R + V G C
Sbjct: 532 ICKAQNSVGHTLITVPVMIVAYPPRITNRPPRSI-----------VTRTGAAFQLHCVAL 580
Query: 121 GNPSPWASWD-KDGSIITPSA--RITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGR 177
G P P +W+ D S+++ ++ R E+ + L I D GIY+ T +N LG
Sbjct: 581 GVPKPEITWEMPDHSLLSTASKERTHGSEQLHLQGTLVIQNPQTSDSGIYKCTAKNPLGS 640
Query: 178 AEASARLEVI 187
A+ ++VI
Sbjct: 641 DYAATYIQVI 650
Score = 51.6 bits (118), Expect = 2e-06
Identities = 46/181 (25%), Positives = 72/181 (39%), Gaps = 16/181 (8%)
Query: 11 FECQVTGNPDPDIRWFHYAEVIRDCADFESS---YDDGTARLKIKQVTAEDEGTYTCEAS 67
F+C+ G P P++ W + + S + +GT L+I+ V D + C A
Sbjct: 286 FDCRAEGTPSPEVMWIMPDNIFLTAPYYGSRITVHKNGT--LEIRNVRLSDSADFICVAR 343
Query: 68 NCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNK--VVEEGENVTFKCAVKGNPSP 125
N G++ L V R PTF PFN+ V + G++ C+V GNP P
Sbjct: 344 NEGGESVLVVQLEVLEMLR--------RPTFRN-PFNEKIVAQLGKSTALNCSVDGNPPP 394
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
W + + + I + + ED G YR N++G E LE
Sbjct: 395 EIIWILPNGTRFSNGPQSYQYLIASNGSFIISKTTREDAGKYRCAARNKVGYIEKLVILE 454
Query: 186 V 186
+
Sbjct: 455 I 455
Score = 51.2 bits (117), Expect = 3e-06
Identities = 55/192 (28%), Positives = 81/192 (42%), Gaps = 26/192 (13%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYA-EVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
GDT +C+VTG+P P I W + ++I D + + +G+ L I +V D G Y C
Sbjct: 183 GDTAVLDCEVTGDPKPKIFWLLPSNDMISFSIDRYTFHANGS--LTINKVKLLDSGEYVC 240
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVT-----FKCAV 119
A N G +Y +S P + YT N+ V + V F C
Sbjct: 241 VARNPSGDDTK-----MYKLDVVSKP--PLINGLYT---NRTVIKATAVRHSKKHFDCRA 290
Query: 120 KGNPSPWASWDKDGSIITPS----ARITVKEKEEIMRILEIDEVSIEDVGIYRITVENEL 175
+G PSP W +I + +RITV + LEI V + D + NE
Sbjct: 291 EGTPSPEVMWIMPDNIFLTAPYYGSRITVHKNGT----LEIRNVRLSDSADFICVARNEG 346
Query: 176 GRAEASARLEVI 187
G + +LEV+
Sbjct: 347 GESVLVVQLEVL 358
Score = 48.4 bits (110), Expect = 2e-05
Identities = 51/197 (25%), Positives = 81/197 (41%), Gaps = 29/197 (14%)
Query: 6 GDTVEFECQVTGNPDPDIRW-FHYAEVIRDCADFESS---------YDDGTARLKIKQVT 55
G + +C+ +G+P P+I W +I + + S +++GT L +V
Sbjct: 80 GKDFQVDCKASGSPVPEISWSLPDGTMINNAMQADDSGHRTRRYTLFNNGT--LYFNKVG 137
Query: 56 AEDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPG-RQMAPTFYTYPFNKVVEEGENVT 114
+EG YTC A N LGK + L V ++P RQ T NK ++ G+
Sbjct: 138 VAEEGDYTCYAQNTLGKDEMKVHLTVI----TAAPRIRQSNKT------NKRIKAGDTAV 187
Query: 115 FKCAVKGNPSPWASW--DKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVE 172
C V G+P P W + I R T L I++V + D G Y
Sbjct: 188 LDCEVTGDPKPKIFWLLPSNDMISFSIDRYTFHANGS----LTINKVKLLDSGEYVCVAR 243
Query: 173 NELGRAEASARLEVITR 189
N G +L+V+++
Sbjct: 244 NPSGDDTKMYKLDVVSK 260
Score = 44.8 bits (101), Expect = 2e-04
Identities = 44/154 (28%), Positives = 63/154 (40%), Gaps = 18/154 (11%)
Query: 42 YDDGTARLKIKQVTAEDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTY 101
Y +G+ L I VT +D G Y C A N +G L++ H P A +
Sbjct: 23 YPNGS--LFIGSVTEKDSGVYLCVARNKMGDD-----LILMHVSLRLKP----AKIDHKQ 71
Query: 102 PFNKVVEEGENVTFKCAVKGNPSPWASWD-KDGSIIT------PSARITVKEKEEIMRIL 154
F K V G++ C G+P P SW DG++I S T + L
Sbjct: 72 YFRKQVLHGKDFQVDCKASGSPVPEISWSLPDGTMINNAMQADDSGHRTRRYTLFNNGTL 131
Query: 155 EIDEVSIEDVGIYRITVENELGRAEASARLEVIT 188
++V + + G Y +N LG+ E L VIT
Sbjct: 132 YFNKVGVAEEGDYTCYAQNTLGKDEMKVHLTVIT 165
Score = 43.6 bits (98), Expect = 6e-04
Identities = 45/175 (25%), Positives = 63/175 (36%), Gaps = 17/175 (9%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYD---DGTARLKIKQVTAEDEGTY 62
G + C V GNP P+I W R ++ SY I + T ED G Y
Sbjct: 379 GKSTALNCSVDGNPPPEIIWI-LPNGTR-FSNGPQSYQYLIASNGSFIISKTTREDAGKY 436
Query: 63 TCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTY-PFNKVVEEGENVTFKCAVKG 121
C A N +G + L + G++ P TY P GE+++ C G
Sbjct: 437 RCAARNKVGYIEKLVILEI---------GQK--PVILTYAPGTVKGISGESLSLHCVSDG 485
Query: 122 NPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG 176
P P W + +I K L I E + D G Y +N +G
Sbjct: 486 IPKPNIKWTMPSGYVVDRPQINGKYILHDNGTLVIKEATAYDRGNYICKAQNSVG 540
>BC036769-1|AAH36769.1| 504|Homo sapiens fibroblast growth factor
receptor-like 1 protein.
Length = 504
Score = 66.9 bits (156), Expect = 5e-11
Identities = 62/205 (30%), Positives = 82/205 (40%), Gaps = 26/205 (12%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G TV +C V G+P P W I G LK+KQV ED G Y C+
Sbjct: 44 GRTVRLQCPVEGDPPPLTMWTKDGRTIHSGWSRFRVLPQG---LKVKQVEREDAGVYVCK 100
Query: 66 ASNCLGKAKSNACLVVYH-----TRRL---SSPGRQMAPTF-------YTYPF---NKVV 107
A+N G N LVV L SS G Q P +T P +V+
Sbjct: 101 ATNGFGSLSVNYTLVVLDDISPGKESLGPDSSSGGQEDPASQQWARPRFTQPSKMRRRVI 160
Query: 108 EE--GENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVG 165
G +V KC G+P P +W KD +T R E + L + + ED G
Sbjct: 161 ARPVGSSVRLKCVASGHPRPDITWMKDDQALT---RPEAAEPRKKKWTLSLKNLRPEDSG 217
Query: 166 IYRITVENELGRAEASARLEVITRS 190
Y V N G A+ +++VI R+
Sbjct: 218 KYTCRVSNRAGAINATYKVDVIQRT 242
Score = 54.8 bits (126), Expect = 2e-07
Identities = 37/126 (29%), Positives = 53/126 (42%), Gaps = 8/126 (6%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G +V +C +G+P PDI W + + E T L +K + ED G YTC
Sbjct: 165 GSSVRLKCVASGHPRPDITWMKDDQALTRPEAAEPRKKKWT--LSLKNLRPEDSGKYTCR 222
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
SN G + + V R S P T+P N V+ G +F+C V+ + P
Sbjct: 223 VSNRAGAINATYKVDVIQRTR-SKP-----VLTGTHPVNTTVDFGGTTSFQCKVRSDVKP 276
Query: 126 WASWDK 131
W K
Sbjct: 277 VIQWLK 282
Score = 39.9 bits (89), Expect = 0.007
Identities = 25/84 (29%), Positives = 38/84 (45%), Gaps = 6/84 (7%)
Query: 105 KVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPS-ARITVKEKEEIMRILEIDEVSIED 163
+V G V +C V+G+P P W KDG I +R V + + L++ +V ED
Sbjct: 39 QVARLGRTVRLQCPVEGDPPPLTMWTKDGRTIHSGWSRFRV-----LPQGLKVKQVERED 93
Query: 164 VGIYRITVENELGRAEASARLEVI 187
G+Y N G + L V+
Sbjct: 94 AGVYVCKATNGFGSLSVNYTLVVL 117
>AY358303-1|AAQ88670.1| 504|Homo sapiens FGFRL1 protein.
Length = 504
Score = 66.9 bits (156), Expect = 5e-11
Identities = 62/205 (30%), Positives = 82/205 (40%), Gaps = 26/205 (12%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G TV +C V G+P P W I G LK+KQV ED G Y C+
Sbjct: 44 GRTVRLQCPVEGDPPPLTMWTKDGRTIHSGWSRFRVLPQG---LKVKQVEREDAGVYVCK 100
Query: 66 ASNCLGKAKSNACLVVYH-----TRRL---SSPGRQMAPTF-------YTYPF---NKVV 107
A+N G N LVV L SS G Q P +T P +V+
Sbjct: 101 ATNGFGSLSVNYTLVVLDDISPGKESLGPDSSSGGQEDPASQQWARPRFTQPSKMRRRVI 160
Query: 108 EE--GENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVG 165
G +V KC G+P P +W KD +T R E + L + + ED G
Sbjct: 161 ARPVGSSVRLKCVASGHPRPDITWMKDDQALT---RPEAAEPRKKKWTLSLKNLRPEDSG 217
Query: 166 IYRITVENELGRAEASARLEVITRS 190
Y V N G A+ +++VI R+
Sbjct: 218 KYTCRVSNRAGAINATYKVDVIQRT 242
Score = 54.8 bits (126), Expect = 2e-07
Identities = 37/126 (29%), Positives = 53/126 (42%), Gaps = 8/126 (6%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G +V +C +G+P PDI W + + E T L +K + ED G YTC
Sbjct: 165 GSSVRLKCVASGHPRPDITWMKDDQALTRPEAAEPRKKKWT--LSLKNLRPEDSGKYTCR 222
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
SN G + + V R S P T+P N V+ G +F+C V+ + P
Sbjct: 223 VSNRAGAINATYKVDVIQRTR-SKP-----VLTGTHPVNTTVDFGGTTSFQCKVRSDVKP 276
Query: 126 WASWDK 131
W K
Sbjct: 277 VIQWLK 282
Score = 39.9 bits (89), Expect = 0.007
Identities = 25/84 (29%), Positives = 38/84 (45%), Gaps = 6/84 (7%)
Query: 105 KVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPS-ARITVKEKEEIMRILEIDEVSIED 163
+V G V +C V+G+P P W KDG I +R V + + L++ +V ED
Sbjct: 39 QVARLGRTVRLQCPVEGDPPPLTMWTKDGRTIHSGWSRFRV-----LPQGLKVKQVERED 93
Query: 164 VGIYRITVENELGRAEASARLEVI 187
G+Y N G + L V+
Sbjct: 94 AGVYVCKATNGFGSLSVNYTLVVL 117
>AK222718-1|BAD96438.1| 820|Homo sapiens fibroblast growth factor
receptor 1 isoform 2 precursor variant protein.
Length = 820
Score = 66.9 bits (156), Expect = 5e-11
Identities = 59/197 (29%), Positives = 82/197 (41%), Gaps = 27/197 (13%)
Query: 8 TVEFECQVTGNPDPDIRWFHYAEVIRD---CADFESSYDDGTARLKIKQVTAEDEGTYTC 64
TV+F+C +G P+P +RW + + ++ Y T + + V D+G YTC
Sbjct: 171 TVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRY--ATWSIIMDSVVPFDKGNYTC 228
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
N G L V SP R + P NK V G NV F C V +P
Sbjct: 229 IVENEYGSINHTYQLDVVER----SPHRPILQA--GLPANKTVALGSNVEFMCKVYSDPQ 282
Query: 125 PWASWDK----DGSIITP----------SARITVKEKEEIMRILEIDEVSIEDVGIYRIT 170
P W K +GS I P +A + +KE M +L + VS ED G Y
Sbjct: 283 PHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKE--MEVLHLRNVSFEDAGEYTCL 340
Query: 171 VENELGRAEASARLEVI 187
N +G + SA L V+
Sbjct: 341 AGNSIGLSHHSAWLTVL 357
Score = 47.2 bits (107), Expect = 4e-05
Identities = 28/84 (33%), Positives = 38/84 (45%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
V + V FKC G P+P W K+G P RI + + +D V D G
Sbjct: 166 VPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPFDKGN 225
Query: 167 YRITVENELGRAEASARLEVITRS 190
Y VENE G + +L+V+ RS
Sbjct: 226 YTCIVENEYGSINHTYQLDVVERS 249
Score = 41.1 bits (92), Expect = 0.003
Identities = 29/90 (32%), Positives = 41/90 (45%), Gaps = 15/90 (16%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEV--------------IRDCADFESSYDDGTARLKI 51
G VEF C+V +P P I+W + EV I A ++ D L +
Sbjct: 268 GSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTT-DKEMEVLHL 326
Query: 52 KQVTAEDEGTYTCEASNCLGKAKSNACLVV 81
+ V+ ED G YTC A N +G + +A L V
Sbjct: 327 RNVSFEDAGEYTCLAGNSIGLSHHSAWLTV 356
>AK172829-1|BAD18794.1| 440|Homo sapiens protein ( Homo sapiens
cDNA FLJ23990 fis, clone HRC08053, highly similar to
Homo sapiens fibroblast growth factor receptor-like 1
(FGFRL1). ).
Length = 440
Score = 66.9 bits (156), Expect = 5e-11
Identities = 62/205 (30%), Positives = 82/205 (40%), Gaps = 26/205 (12%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G TV +C V G+P P W I G LK+KQV ED G Y C+
Sbjct: 14 GRTVRLQCPVEGDPPPLTMWTKDGRTIHSGWSRFRVLPQG---LKVKQVEREDAGVYVCK 70
Query: 66 ASNCLGKAKSNACLVVYH-----TRRL---SSPGRQMAPTF-------YTYPF---NKVV 107
A+N G N LVV L SS G Q P +T P +V+
Sbjct: 71 ATNGFGSLSVNYTLVVLDDISPGKESLGPDSSSGGQEDPASQQWARPRFTQPSKMRRRVI 130
Query: 108 EE--GENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVG 165
G +V KC G+P P +W KD +T R E + L + + ED G
Sbjct: 131 ARPVGSSVRLKCVASGHPRPDITWMKDDQALT---RPEAAEPRKKKWTLSLKNLRPEDSG 187
Query: 166 IYRITVENELGRAEASARLEVITRS 190
Y V N G A+ +++VI R+
Sbjct: 188 KYTCRVSNRAGAINATYKVDVIQRT 212
Score = 54.8 bits (126), Expect = 2e-07
Identities = 37/126 (29%), Positives = 53/126 (42%), Gaps = 8/126 (6%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G +V +C +G+P PDI W + + E T L +K + ED G YTC
Sbjct: 135 GSSVRLKCVASGHPRPDITWMKDDQALTRPEAAEPRKKKWT--LSLKNLRPEDSGKYTCR 192
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
SN G + + V R S P T+P N V+ G +F+C V+ + P
Sbjct: 193 VSNRAGAINATYKVDVIQRTR-SKP-----VLTGTHPVNTTVDFGGTTSFQCKVRSDVKP 246
Query: 126 WASWDK 131
W K
Sbjct: 247 VIQWLK 252
Score = 39.9 bits (89), Expect = 0.007
Identities = 25/84 (29%), Positives = 38/84 (45%), Gaps = 6/84 (7%)
Query: 105 KVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPS-ARITVKEKEEIMRILEIDEVSIED 163
+V G V +C V+G+P P W KDG I +R V + + L++ +V ED
Sbjct: 9 QVARLGRTVRLQCPVEGDPPPLTMWTKDGRTIHSGWSRFRV-----LPQGLKVKQVERED 63
Query: 164 VGIYRITVENELGRAEASARLEVI 187
G+Y N G + L V+
Sbjct: 64 AGVYVCKATNGFGSLSVNYTLVVL 87
>AJ277437-1|CAC14171.1| 504|Homo sapiens FGFR-like protein protein.
Length = 504
Score = 66.9 bits (156), Expect = 5e-11
Identities = 62/205 (30%), Positives = 82/205 (40%), Gaps = 26/205 (12%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G TV +C V G+P P W I G LK+KQV ED G Y C+
Sbjct: 44 GRTVRLQCPVEGDPPPLTMWTKDGRTIHSGWSRFRVLPQG---LKVKQVEREDAGVYVCK 100
Query: 66 ASNCLGKAKSNACLVVYH-----TRRL---SSPGRQMAPTF-------YTYPF---NKVV 107
A+N G N LVV L SS G Q P +T P +V+
Sbjct: 101 ATNGFGSLSVNYTLVVLDDISPGKESLGPDSSSGGQEDPASQQWARPRFTQPSKMRRRVI 160
Query: 108 EE--GENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVG 165
G +V KC G+P P +W KD +T R E + L + + ED G
Sbjct: 161 ARPVGSSVRLKCVASGHPRPDITWMKDDQALT---RPEAAEPRKKKWTLSLKNLRPEDSG 217
Query: 166 IYRITVENELGRAEASARLEVITRS 190
Y V N G A+ +++VI R+
Sbjct: 218 KYTCRVSNRAGAINATYKVDVIQRT 242
Score = 54.8 bits (126), Expect = 2e-07
Identities = 37/126 (29%), Positives = 53/126 (42%), Gaps = 8/126 (6%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G +V +C +G+P PDI W + + E T L +K + ED G YTC
Sbjct: 165 GSSVRLKCVASGHPRPDITWMKDDQALTRPEAAEPRKKKWT--LSLKNLRPEDSGKYTCR 222
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
SN G + + V R S P T+P N V+ G +F+C V+ + P
Sbjct: 223 VSNRAGAINATYKVDVIQRTR-SKP-----VLTGTHPVNTTVDFGGTTSFQCKVRSDVKP 276
Query: 126 WASWDK 131
W K
Sbjct: 277 VIQWLK 282
Score = 39.9 bits (89), Expect = 0.007
Identities = 25/84 (29%), Positives = 38/84 (45%), Gaps = 6/84 (7%)
Query: 105 KVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPS-ARITVKEKEEIMRILEIDEVSIED 163
+V G V +C V+G+P P W KDG I +R V + + L++ +V ED
Sbjct: 39 QVARLGRTVRLQCPVEGDPPPLTMWTKDGRTIHSGWSRFRV-----LPQGLKVKQVERED 93
Query: 164 VGIYRITVENELGRAEASARLEVI 187
G+Y N G + L V+
Sbjct: 94 AGVYVCKATNGFGSLSVNYTLVVL 117
>AF312678-1|AAK15273.1| 497|Homo sapiens FGF homologous factor
receptor protein.
Length = 497
Score = 66.9 bits (156), Expect = 5e-11
Identities = 62/205 (30%), Positives = 82/205 (40%), Gaps = 26/205 (12%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G TV +C V G+P P W I G LK+KQV ED G Y C+
Sbjct: 44 GRTVRLQCPVEGDPPPLTMWTKDGRTIHSGWSRFRVLPQG---LKVKQVEREDAGVYVCK 100
Query: 66 ASNCLGKAKSNACLVVYH-----TRRL---SSPGRQMAPTF-------YTYPF---NKVV 107
A+N G N LVV L SS G Q P +T P +V+
Sbjct: 101 ATNGFGSLSVNYTLVVLDDISPGKESLGPDSSSGGQEDPASQQWARPRFTQPSKMRRRVI 160
Query: 108 EE--GENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVG 165
G +V KC G+P P +W KD +T R E + L + + ED G
Sbjct: 161 ARPVGSSVRLKCVASGHPRPDITWMKDDQALT---RPEAAEPRKKKWTLSLKNLRPEDSG 217
Query: 166 IYRITVENELGRAEASARLEVITRS 190
Y V N G A+ +++VI R+
Sbjct: 218 KYTCRVSNRAGAINATYKVDVIQRT 242
Score = 54.8 bits (126), Expect = 2e-07
Identities = 37/126 (29%), Positives = 53/126 (42%), Gaps = 8/126 (6%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G +V +C +G+P PDI W + + E T L +K + ED G YTC
Sbjct: 165 GSSVRLKCVASGHPRPDITWMKDDQALTRPEAAEPRKKKWT--LSLKNLRPEDSGKYTCR 222
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
SN G + + V R S P T+P N V+ G +F+C V+ + P
Sbjct: 223 VSNRAGAINATYKVDVIQRTR-SKP-----VLTGTHPVNTTVDFGGTTSFQCKVRSDVKP 276
Query: 126 WASWDK 131
W K
Sbjct: 277 VIQWLK 282
Score = 39.9 bits (89), Expect = 0.007
Identities = 25/84 (29%), Positives = 38/84 (45%), Gaps = 6/84 (7%)
Query: 105 KVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPS-ARITVKEKEEIMRILEIDEVSIED 163
+V G V +C V+G+P P W KDG I +R V + + L++ +V ED
Sbjct: 39 QVARLGRTVRLQCPVEGDPPPLTMWTKDGRTIHSGWSRFRV-----LPQGLKVKQVERED 93
Query: 164 VGIYRITVENELGRAEASARLEVI 187
G+Y N G + L V+
Sbjct: 94 AGVYVCKATNGFGSLSVNYTLVVL 117
>AF279689-1|AAK26742.1| 504|Homo sapiens fibroblast growth factor
receptor 5 protein.
Length = 504
Score = 66.9 bits (156), Expect = 5e-11
Identities = 62/205 (30%), Positives = 82/205 (40%), Gaps = 26/205 (12%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G TV +C V G+P P W I G LK+KQV ED G Y C+
Sbjct: 44 GRTVRLQCPVEGDPPPLTMWTKDGRTIHSGWSRFRVLPQG---LKVKQVEREDAGVYVCK 100
Query: 66 ASNCLGKAKSNACLVVYH-----TRRL---SSPGRQMAPTF-------YTYPF---NKVV 107
A+N G N LVV L SS G Q P +T P +V+
Sbjct: 101 ATNGFGSLSVNYTLVVLDDISPGKESLGPDSSSGGQEDPASQQWARPRFTQPSKMRRRVI 160
Query: 108 EE--GENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVG 165
G +V KC G+P P +W KD +T R E + L + + ED G
Sbjct: 161 ARPVGSSVRLKCVASGHPRPDITWMKDDQALT---RPEAAEPRKKKWTLSLKNLRPEDSG 217
Query: 166 IYRITVENELGRAEASARLEVITRS 190
Y V N G A+ +++VI R+
Sbjct: 218 KYTCRVSNRAGAINATYKVDVIQRT 242
Score = 54.8 bits (126), Expect = 2e-07
Identities = 37/126 (29%), Positives = 53/126 (42%), Gaps = 8/126 (6%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G +V +C +G+P PDI W + + E T L +K + ED G YTC
Sbjct: 165 GSSVRLKCVASGHPRPDITWMKDDQALTRPEAAEPRKKKWT--LSLKNLRPEDSGKYTCR 222
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
SN G + + V R S P T+P N V+ G +F+C V+ + P
Sbjct: 223 VSNRAGAINATYKVDVIQRTR-SKP-----VLTGTHPVNTTVDFGGTTSFQCKVRSDVKP 276
Query: 126 WASWDK 131
W K
Sbjct: 277 VIQWLK 282
Score = 39.9 bits (89), Expect = 0.007
Identities = 25/84 (29%), Positives = 38/84 (45%), Gaps = 6/84 (7%)
Query: 105 KVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPS-ARITVKEKEEIMRILEIDEVSIED 163
+V G V +C V+G+P P W KDG I +R V + + L++ +V ED
Sbjct: 39 QVARLGRTVRLQCPVEGDPPPLTMWTKDGRTIHSGWSRFRV-----LPQGLKVKQVERED 93
Query: 164 VGIYRITVENELGRAEASARLEVI 187
G+Y N G + L V+
Sbjct: 94 AGVYVCKATNGFGSLSVNYTLVVL 117
>AF069604-1|AAD15924.1| 560|Homo sapiens myosin light chain kinase
isoform 4 protein.
Length = 560
Score = 66.5 bits (155), Expect = 7e-11
Identities = 29/74 (39%), Positives = 42/74 (56%), Gaps = 1/74 (1%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYD-DGTARLKIKQVTAEDEGTYT 63
+G F+C++ G PDP++ WF + IR+ F+ YD DG L I V +D+ YT
Sbjct: 468 EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 527
Query: 64 CEASNCLGKAKSNA 77
C+A N LG+A A
Sbjct: 528 CKAVNSLGEATCTA 541
Score = 39.9 bits (89), Expect = 0.007
Identities = 24/76 (31%), Positives = 31/76 (40%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
V EG F C ++G P P W KD I S + E+ L I +V +D
Sbjct: 466 VVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAK 525
Query: 167 YRITVENELGRAEASA 182
Y N LG A +A
Sbjct: 526 YTCKAVNSLGEATCTA 541
>AK130921-1|BAC85460.1| 572|Homo sapiens protein ( Homo sapiens
cDNA FLJ27411 fis, clone WMC04903, highly similar to
Myosin light chain kinase, smooth muscle and non-muscle
isozymes ).
Length = 572
Score = 66.1 bits (154), Expect = 9e-11
Identities = 30/78 (38%), Positives = 44/78 (56%), Gaps = 1/78 (1%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYD-DGTARLKIKQVTAEDEGTYT 63
+G F+C++ G PDP++ W + IR+ F+ YD DG L I V +D+ YT
Sbjct: 480 EGSAARFDCKIEGYPDPEVVWSKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 539
Query: 64 CEASNCLGKAKSNACLVV 81
C+A N LG+A A L+V
Sbjct: 540 CKAVNSLGEATCTAELIV 557
Score = 44.0 bits (99), Expect = 4e-04
Identities = 27/82 (32%), Positives = 34/82 (41%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
V EG F C ++G P P W KD I S + E+ L I +V +D
Sbjct: 478 VVEGSAARFDCKIEGYPDPEVVWSKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAK 537
Query: 167 YRITVENELGRAEASARLEVIT 188
Y N LG A +A L V T
Sbjct: 538 YTCKAVNSLGEATCTAELIVET 559
>AK074780-1|BAC11205.1| 570|Homo sapiens protein ( Homo sapiens
cDNA FLJ90299 fis, clone NT2RP2000514, highly similar to
Homo sapiens roundabout 2 (robo2) mRNA. ).
Length = 570
Score = 65.7 bits (153), Expect = 1e-10
Identities = 45/133 (33%), Positives = 62/133 (46%), Gaps = 11/133 (8%)
Query: 58 DEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKC 117
DEGTY C A N +GK +++A L V R +P P F P +++V +G VTF C
Sbjct: 4 DEGTYMCIAENRVGKMEASATLTV--RARPVAP-----PQFVVRPRDQIVAQGRTVTFPC 56
Query: 118 AVKGNPSPWASWDKDGS--IITPSARITVKEKEEIMRI--LEIDEVSIEDVGIYRITVEN 173
KGNP P W K+GS ++ P+ + + L I + D G Y
Sbjct: 57 ETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALT 116
Query: 174 ELGRAEASARLEV 186
G A A+LEV
Sbjct: 117 VAGSILAKAQLEV 129
Score = 56.0 bits (129), Expect = 1e-07
Identities = 53/192 (27%), Positives = 73/192 (38%), Gaps = 16/192 (8%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAE---VIRDCADFESSYDD--GTARLKIKQVTAEDEG 60
G TV F C+ GNP P + W + + +S T L I + D G
Sbjct: 49 GRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAG 108
Query: 61 TYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVK 120
Y C+A G + A L V P P P N+ + KC
Sbjct: 109 YYICQALTVAGSILAKAQLEVTDVLTDRPP-----PIILQGPANQTLAVDGTALLKCKAT 163
Query: 121 GNPSPWASWDKDG-SIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAE 179
G+P P SW K+G + R T++E+ L+I + I D G Y + G
Sbjct: 164 GDPLPVISWLKEGFTFPGRDPRATIQEQ----GTLQIKNLRISDTGTYTCVATSSSGETS 219
Query: 180 ASARLEVITRSG 191
SA L+V T SG
Sbjct: 220 WSAVLDV-TESG 230
Score = 41.9 bits (94), Expect = 0.002
Identities = 27/80 (33%), Positives = 39/80 (48%), Gaps = 3/80 (3%)
Query: 2 LSCDGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGT 61
L+ DG T +C+ TG+P P I W + + GT L+IK + D GT
Sbjct: 150 LAVDG-TALLKCKATGDPLPVISWLKEGFTFPGRDPRATIQEQGT--LQIKNLRISDTGT 206
Query: 62 YTCEASNCLGKAKSNACLVV 81
YTC A++ G+ +A L V
Sbjct: 207 YTCVATSSSGETSWSAVLDV 226
>AB040947-1|BAA96038.1| 1598|Homo sapiens KIAA1514 protein protein.
Length = 1598
Score = 65.7 bits (153), Expect = 1e-10
Identities = 53/185 (28%), Positives = 73/185 (39%), Gaps = 17/185 (9%)
Query: 9 VEFECQVTGNPDPDIRWFHYAEVIR--DCADFESSYDDGTARLKIKQVTAEDEGTYTCEA 66
V+ CQ G P P I W+ A V+ F D G L+I + +D G + C A
Sbjct: 3 VDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRNDGG---LQISGLVPDDTGMFQCFA 59
Query: 67 SNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPW 126
N G+ +++ L V +AP P + V +G +V C G P P
Sbjct: 60 RNAAGEVQTSTYLAV----------TSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPA 109
Query: 127 ASWDKDGSIITPSARITVKEKEEI-MRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
+W K G I S + + + L I I D G Y N G EASA L
Sbjct: 110 ITWQK-GERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLV 168
Query: 186 VITRS 190
V R+
Sbjct: 169 VWART 173
Score = 52.8 bits (121), Expect = 9e-07
Identities = 47/185 (25%), Positives = 76/185 (41%), Gaps = 16/185 (8%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDD-GTARLKIKQVTAEDEGTYT 63
DG +V C+ +G P P I W ++ + + + L I D GTYT
Sbjct: 92 DGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYT 151
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
C A+N G +++A LVV+ R++ P P ++ V +G + C V +P
Sbjct: 152 CLATNSRGVDEASADLVVWARTRITKP-----------PQDQSVIKGTQASMVCGVTHDP 200
Query: 124 SPWAS--WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEAS 181
W+KDG+ + + ++ L I + D+G Y V + G S
Sbjct: 201 RVTIRYIWEKDGATLGTESHPRIRLDRN--GSLHISQTWSGDIGTYTCRVISAGGNDSRS 258
Query: 182 ARLEV 186
A L V
Sbjct: 259 AHLRV 263
>BC117370-1|AAI17371.1| 1065|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 2 protein.
Length = 1065
Score = 64.9 bits (151), Expect = 2e-10
Identities = 44/142 (30%), Positives = 65/142 (45%), Gaps = 10/142 (7%)
Query: 46 TARLKIKQVTAEDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNK 105
T+ L + V DEG Y C +N G SN ++++ +M P+F P +
Sbjct: 562 TSILHLFNVNFTDEGKYQCIVTNHFG---SN------YSQKAKLTVNEM-PSFLKTPMDL 611
Query: 106 VVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVG 165
+ G +CA +G+P+P SW KDG P+AR + I V IED+G
Sbjct: 612 TIRTGAMARLECAAEGHPAPQISWQKDGGTDFPAARERRMHVMPEDDVFFIANVKIEDMG 671
Query: 166 IYRITVENELGRAEASARLEVI 187
IY +N G A+A L V+
Sbjct: 672 IYSCMAQNTAGGLSANASLTVL 693
Score = 61.3 bits (142), Expect = 3e-09
Identities = 50/186 (26%), Positives = 71/186 (38%), Gaps = 19/186 (10%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSY---DDGTARLKIKQVTAEDEGTY 62
G EC G+P P I W A + +D I V ED G Y
Sbjct: 616 GAMARLECAAEGHPAPQISWQKDGGTDFPAARERRMHVMPEDDV--FFIANVKIEDMGIY 673
Query: 63 TCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGN 122
+C A N G +NA L V T P+F +K V GE +C G+
Sbjct: 674 SCMAQNTAGGLSANASLTVLET-----------PSFIRPLEDKTVTRGETAVLQCIAGGS 722
Query: 123 PSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASA 182
P+P +W KD + + R +++ I+ + +ED G Y + N LG
Sbjct: 723 PAPRLNWTKDDGPLLVTERHFFAAANQLLIIV---DAGLEDAGKYTCIMSNTLGTERGHI 779
Query: 183 RLEVIT 188
L VI+
Sbjct: 780 YLNVIS 785
>BC117368-1|AAI17369.1| 1065|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 2 protein.
Length = 1065
Score = 64.9 bits (151), Expect = 2e-10
Identities = 44/142 (30%), Positives = 65/142 (45%), Gaps = 10/142 (7%)
Query: 46 TARLKIKQVTAEDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNK 105
T+ L + V DEG Y C +N G SN ++++ +M P+F P +
Sbjct: 562 TSILHLFNVNFTDEGKYQCIVTNHFG---SN------YSQKAKLTVNEM-PSFLKTPMDL 611
Query: 106 VVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVG 165
+ G +CA +G+P+P SW KDG P+AR + I V IED+G
Sbjct: 612 TIRTGAMARLECAAEGHPAPQISWQKDGGTDFPAARERRMHVMPEDDVFFIANVKIEDMG 671
Query: 166 IYRITVENELGRAEASARLEVI 187
IY +N G A+A L V+
Sbjct: 672 IYSCMAQNTAGGLSANASLTVL 693
Score = 61.3 bits (142), Expect = 3e-09
Identities = 50/186 (26%), Positives = 71/186 (38%), Gaps = 19/186 (10%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSY---DDGTARLKIKQVTAEDEGTY 62
G EC G+P P I W A + +D I V ED G Y
Sbjct: 616 GAMARLECAAEGHPAPQISWQKDGGTDFPAARERRMHVMPEDDV--FFIANVKIEDMGIY 673
Query: 63 TCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGN 122
+C A N G +NA L V T P+F +K V GE +C G+
Sbjct: 674 SCMAQNTAGGLSANASLTVLET-----------PSFIRPLEDKTVTRGETAVLQCIAGGS 722
Query: 123 PSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASA 182
P+P +W KD + + R +++ I+ + +ED G Y + N LG
Sbjct: 723 PAPRLNWTKDDGPLLVTERHFFAAANQLLIIV---DAGLEDAGKYTCIMSNTLGTERGHI 779
Query: 183 RLEVIT 188
L VI+
Sbjct: 780 YLNVIS 785
>AY630258-1|AAU05741.1| 1150|Homo sapiens shen-dan protein.
Length = 1150
Score = 64.9 bits (151), Expect = 2e-10
Identities = 52/180 (28%), Positives = 75/180 (41%), Gaps = 17/180 (9%)
Query: 8 TVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEAS 67
TV EC TGNP P I W + + D ++ G L I V + G Y C A+
Sbjct: 251 TVVLECMATGNPKPIISW---SRLDHKSIDVFNTRVLGNGNLMISDVRLQHAGVYVCRAT 307
Query: 68 NCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWA 127
+ V T + +P P+F +P + F C +G PSP
Sbjct: 308 T----PGTRNFTVAMATLTVLAP-----PSFVEWPESLTRPRAGTARFVCQAEGIPSPKM 358
Query: 128 SWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVI 187
SW K+G I + RI + + L I+++ ED IY+ EN G + ARL V+
Sbjct: 359 SWLKNGRKIHSNGRIKMYNSK-----LVINQIIPEDDAIYQCMAENSQGSILSRARLTVV 413
Score = 49.2 bits (112), Expect = 1e-05
Identities = 34/128 (26%), Positives = 50/128 (39%), Gaps = 6/128 (4%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
+G F C+++ +P I W + D ++ G L+I V+ D G Y C
Sbjct: 148 EGGVARFACKISSHPPAVITWEFNRTTLPMTMDRITALPTGV--LQIYDVSQRDSGNYRC 205
Query: 65 EASNCLGKAKS-NACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
A+ + KS A L V + S PT P N + V +C GNP
Sbjct: 206 IAATVAHRRKSMEASLTVIPAKESKS---FHTPTIIAGPQNITTSLHQTVVLECMATGNP 262
Query: 124 SPWASWDK 131
P SW +
Sbjct: 263 KPIISWSR 270
Score = 34.3 bits (75), Expect = 0.34
Identities = 45/194 (23%), Positives = 71/194 (36%), Gaps = 20/194 (10%)
Query: 7 DTVEFECQVTGNPDPDIRWFHYAEVIRDCADFE--SSYDDGTARLKIKQVTAEDEGTYTC 64
D V +CQ G + W + + E S+ + ++ ++ DEG Y C
Sbjct: 54 DPVVLDCQAHGEVPIKVTWLKNGAKMSENKRIEVLSNGSLYISEVEGRRGEQSDEGFYQC 113
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
A N G S + T F P + V EG F C + +P
Sbjct: 114 LAMNKYGAILSQKAHLALST----------ISAFEVQPISTEVHEGGVARFACKISSHPP 163
Query: 125 PWASWDKDGSIITPSA-RITVKEKEEIMRILEIDEVSIEDVGIYR---ITVENELGRAEA 180
+W+ + + + + RIT +L+I +VS D G YR TV + EA
Sbjct: 164 AVITWEFNRTTLPMTMDRITALP----TGVLQIYDVSQRDSGNYRCIAATVAHRRKSMEA 219
Query: 181 SARLEVITRSGKFY 194
S + S F+
Sbjct: 220 SLTVIPAKESKSFH 233
>AL357055-1|CAH73254.1| 1065|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 2 protein.
Length = 1065
Score = 64.9 bits (151), Expect = 2e-10
Identities = 44/142 (30%), Positives = 65/142 (45%), Gaps = 10/142 (7%)
Query: 46 TARLKIKQVTAEDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNK 105
T+ L + V DEG Y C +N G SN ++++ +M P+F P +
Sbjct: 562 TSILHLFNVNFTDEGKYQCIVTNHFG---SN------YSQKAKLTVNEM-PSFLKTPMDL 611
Query: 106 VVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVG 165
+ G +CA +G+P+P SW KDG P+AR + I V IED+G
Sbjct: 612 TIRTGAMARLECAAEGHPAPQISWQKDGGTDFPAARERRMHVMPEDDVFFIANVKIEDMG 671
Query: 166 IYRITVENELGRAEASARLEVI 187
IY +N G A+A L V+
Sbjct: 672 IYSCMAQNTAGGLSANASLTVL 693
Score = 61.3 bits (142), Expect = 3e-09
Identities = 50/186 (26%), Positives = 71/186 (38%), Gaps = 19/186 (10%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSY---DDGTARLKIKQVTAEDEGTY 62
G EC G+P P I W A + +D I V ED G Y
Sbjct: 616 GAMARLECAAEGHPAPQISWQKDGGTDFPAARERRMHVMPEDDV--FFIANVKIEDMGIY 673
Query: 63 TCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGN 122
+C A N G +NA L V T P+F +K V GE +C G+
Sbjct: 674 SCMAQNTAGGLSANASLTVLET-----------PSFIRPLEDKTVTRGETAVLQCIAGGS 722
Query: 123 PSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASA 182
P+P +W KD + + R +++ I+ + +ED G Y + N LG
Sbjct: 723 PAPRLNWTKDDGPLLVTERHFFAAANQLLIIV---DAGLEDAGKYTCIMSNTLGTERGHI 779
Query: 183 RLEVIT 188
L VI+
Sbjct: 780 YLNVIS 785
>AF202063-1|AAF27432.1| 762|Homo sapiens fibroblast growth factor
receptor 4, soluble-form splice variant protein.
Length = 762
Score = 64.9 bits (151), Expect = 2e-10
Identities = 59/204 (28%), Positives = 82/204 (40%), Gaps = 29/204 (14%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLK-------IKQVTAED 58
G+TV+F C GNP P IRW ++D F G RL+ ++ V D
Sbjct: 165 GNTVKFRCPAAGNPTPTIRW------LKDGQAFHGGNRIGGIRLRHQHWSLVMESVVPSD 218
Query: 59 EGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCA 118
GTYTC N +G + N L V SP R + P N G +V C
Sbjct: 219 RGTYTCLVENAVGSIRYNYLLDVLE----RSPHRPILQA--GLPANTTAVVGSDVELLCK 272
Query: 119 VKGNPSPWASWDK----DGSII----TPSARI--TVKEKEEIMRILEIDEVSIEDVGIYR 168
V + P W K +GS P ++ T + +L + VS ED G Y
Sbjct: 273 VYSDAQPHIQWLKHIVINGSSFGADGFPYVQVLKTADINSSEVEVLYLRNVSAEDAGEYT 332
Query: 169 ITVENELGRAEASARLEVITRSGK 192
N +G + SA L V+ +G+
Sbjct: 333 CLAGNSIGLSYQSAWLTVLPGTGR 356
Score = 46.8 bits (106), Expect = 6e-05
Identities = 33/103 (32%), Positives = 44/103 (42%), Gaps = 6/103 (5%)
Query: 93 QMAPTFYTYPFNK-----VVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEK 147
Q AP ++T+P V G V F+C GNP+P W KDG RI
Sbjct: 144 QQAP-YWTHPQRMEKKLHAVPAGNTVKFRCPAAGNPTPTIRWLKDGQAFHGGNRIGGIRL 202
Query: 148 EEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVITRS 190
L ++ V D G Y VEN +G + L+V+ RS
Sbjct: 203 RHQHWSLVMESVVPSDRGTYTCLVENAVGSIRYNYLLDVLERS 245
>AB018349-1|BAA34526.2| 1073|Homo sapiens KIAA0806 protein protein.
Length = 1073
Score = 64.9 bits (151), Expect = 2e-10
Identities = 44/142 (30%), Positives = 65/142 (45%), Gaps = 10/142 (7%)
Query: 46 TARLKIKQVTAEDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNK 105
T+ L + V DEG Y C +N G SN ++++ +M P+F P +
Sbjct: 570 TSILHLFNVNFTDEGKYQCIVTNHFG---SN------YSQKAKLTVNEM-PSFLKTPMDL 619
Query: 106 VVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVG 165
+ G +CA +G+P+P SW KDG P+AR + I V IED+G
Sbjct: 620 TIRTGAMARLECAAEGHPAPQISWQKDGGTDFPAARERRMHVMPEDDVFFIANVKIEDMG 679
Query: 166 IYRITVENELGRAEASARLEVI 187
IY +N G A+A L V+
Sbjct: 680 IYSCMAQNTAGGLSANASLTVL 701
Score = 61.3 bits (142), Expect = 3e-09
Identities = 50/186 (26%), Positives = 71/186 (38%), Gaps = 19/186 (10%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSY---DDGTARLKIKQVTAEDEGTY 62
G EC G+P P I W A + +D I V ED G Y
Sbjct: 624 GAMARLECAAEGHPAPQISWQKDGGTDFPAARERRMHVMPEDDV--FFIANVKIEDMGIY 681
Query: 63 TCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGN 122
+C A N G +NA L V T P+F +K V GE +C G+
Sbjct: 682 SCMAQNTAGGLSANASLTVLET-----------PSFIRPLEDKTVTRGETAVLQCIAGGS 730
Query: 123 PSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASA 182
P+P +W KD + + R +++ I+ + +ED G Y + N LG
Sbjct: 731 PAPRLNWTKDDGPLLVTERHFFAAANQLLIIV---DAGLEDAGKYTCIMSNTLGTERGHI 787
Query: 183 RLEVIT 188
L VI+
Sbjct: 788 YLNVIS 793
>X57205-1|CAA40490.1| 802|Homo sapiens fibroblast growth factor
receptor protein.
Length = 802
Score = 64.5 bits (150), Expect = 3e-10
Identities = 57/199 (28%), Positives = 79/199 (39%), Gaps = 29/199 (14%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLK-------IKQVTAED 58
G+TV+F C GNP P IRW ++D F G RL+ ++ V D
Sbjct: 165 GNTVKFRCPAAGNPTPTIRW------LKDGQAFHGENRIGGIRLRHQHWSLVMESVVPSD 218
Query: 59 EGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCA 118
GTYTC N +G + N L V SP R + P N G +V C
Sbjct: 219 RGTYTCLVENAVGSIRYNYLLDVLE----RSPHRPILQA--GLPANTTAVVGSDVELLCK 272
Query: 119 VKGNPSPWASWDKD--------GSIITPSARI--TVKEKEEIMRILEIDEVSIEDVGIYR 168
V + P W K G++ P ++ T + +L + VS ED G Y
Sbjct: 273 VYSDAQPHIQWLKHIVINGSSFGAVGFPYVQVLKTADINSSEVEVLYLRNVSAEDAGEYT 332
Query: 169 ITVENELGRAEASARLEVI 187
N +G + SA L V+
Sbjct: 333 CLAGNSIGLSYQSAWLTVL 351
Score = 46.8 bits (106), Expect = 6e-05
Identities = 33/103 (32%), Positives = 44/103 (42%), Gaps = 6/103 (5%)
Query: 93 QMAPTFYTYPFNK-----VVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEK 147
Q AP ++T+P V G V F+C GNP+P W KDG RI
Sbjct: 144 QQAP-YWTHPQRMEKKLHAVPAGNTVKFRCPAAGNPTPTIRWLKDGQAFHGENRIGGIRL 202
Query: 148 EEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVITRS 190
L ++ V D G Y VEN +G + L+V+ RS
Sbjct: 203 RHQHWSLVMESVVPSDRGTYTCLVENAVGSIRYNYLLDVLERS 245
>BX537391-1|CAD97633.1| 143|Homo sapiens hypothetical protein
protein.
Length = 143
Score = 64.5 bits (150), Expect = 3e-10
Identities = 45/144 (31%), Positives = 67/144 (46%), Gaps = 7/144 (4%)
Query: 44 DGTARLKIKQVTAEDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPF 103
+G L I+ VT+ D G YTC A+N G+ + LVV ++ P F
Sbjct: 1 NGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVV------AAKEAHKPPVFIEKLQ 54
Query: 104 NKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSA-RITVKEKEEIMRILEIDEVSIE 162
N V +G V +C V G P P W K+ +T S R+++ + L I + E
Sbjct: 55 NTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKE 114
Query: 163 DVGIYRITVENELGRAEASARLEV 186
D G Y ++ +NE G +ARL+V
Sbjct: 115 DAGWYTVSAKNEAGIVSCTARLDV 138
Score = 47.6 bits (108), Expect = 3e-05
Identities = 32/83 (38%), Positives = 37/83 (44%), Gaps = 2/83 (2%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDD--GTARLKIKQVTAEDEGTY 62
DG V EC+V G P P I W E + D S + D G L I+ T ED G Y
Sbjct: 60 DGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWY 119
Query: 63 TCEASNCLGKAKSNACLVVYHTR 85
T A N G A L VY +R
Sbjct: 120 TVSAKNEAGIVSCTARLDVYISR 142
>AY310398-1|AAP75619.1| 2213|Homo sapiens sidekick-like protein 1
protein.
Length = 2213
Score = 64.5 bits (150), Expect = 3e-10
Identities = 54/185 (29%), Positives = 83/185 (44%), Gaps = 13/185 (7%)
Query: 7 DTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEA 66
+TV+ CQ G P P ++W+ A I + + L+I+++ ED G + C A
Sbjct: 402 ETVDIGCQAMGVPLPTLQWYKDAISISRLQNPRYKVL-ASGGLRIQKLRPEDSGIFQCFA 460
Query: 67 SNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPW 126
SN G+ +++ L V + +AP F P + V +G +C V G P P
Sbjct: 461 SNEGGEIQTHTYLDVTN----------IAPVFTQRPVDTTVTDGMTAILRCEVSGAPKPA 510
Query: 127 ASWDKDGSII-TPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
+W ++ I+ + S RI E L+I V I+D G Y N G ASA L
Sbjct: 511 ITWKRENHILASGSVRIPRFMLLE-SGGLQIAPVFIQDAGNYTCYAANTEGSLNASATLT 569
Query: 186 VITRS 190
V R+
Sbjct: 570 VWNRT 574
Score = 62.9 bits (146), Expect = 8e-10
Identities = 54/188 (28%), Positives = 80/188 (42%), Gaps = 20/188 (10%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRD-CADFESSYDDGTARLKIKQVTAEDEGTYT 63
DG T C+V+G P P I W ++ + L+I V +D G YT
Sbjct: 493 DGMTAILRCEVSGAPKPAITWKRENHILASGSVRIPRFMLLESGGLQIAPVFIQDAGNYT 552
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP 123
C A+N G ++A L V++ + P P + VV +G T C +P
Sbjct: 553 CYAANTEGSLNASATLTVWNRTSIVHP-----------PEDHVVIKGTTATLHCGATHDP 601
Query: 124 --SPWASWDKDGSIITPS--ARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAE 179
S W KD +TPS +RI V++ ++ I + D+G Y + +E G
Sbjct: 602 RVSLRYVWKKDNVALTPSSTSRIVVEKDGSLL----ISQTWSGDIGDYSCEIVSEGGNDS 657
Query: 180 ASARLEVI 187
ARLEVI
Sbjct: 658 RMARLEVI 665
Score = 38.7 bits (86), Expect = 0.016
Identities = 39/142 (27%), Positives = 56/142 (39%), Gaps = 17/142 (11%)
Query: 49 LKIKQVTAEDEGTYTCEAS---NCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNK 105
L I T+ D G Y CEA+ + A++ A L + P F P ++
Sbjct: 347 LTISNPTSADTGPYVCEAALPGSAFEPARATAFLFIIE-----------PPYFTAEPESR 395
Query: 106 V-VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDV 164
+ E E V C G P P W KD I+ S + K L I ++ ED
Sbjct: 396 ISAEVEETVDIGCQAMGVPLPTLQWYKDA--ISISRLQNPRYKVLASGGLRIQKLRPEDS 453
Query: 165 GIYRITVENELGRAEASARLEV 186
GI++ NE G + L+V
Sbjct: 454 GIFQCFASNEGGEIQTHTYLDV 475
>AY358328-1|AAQ88694.1| 1115|Homo sapiens BOC protein.
Length = 1115
Score = 63.7 bits (148), Expect = 5e-10
Identities = 46/179 (25%), Positives = 78/179 (43%), Gaps = 17/179 (9%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G ++ EC +G P P + W + + L I + ED GTY C
Sbjct: 245 GQSLILECVASGIPPPRVTWAKDGSSVTGYNKTRFLLSN----LLIDTTSEEDSGTYRCM 300
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A N +G+ A +++Y+ + P M + P+ G++ C V+GNP P
Sbjct: 301 ADNGVGQP--GAAVILYNVQVFEPPEVTMELSQLVIPW------GQSAKLTCEVRGNPPP 352
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
W ++ + S R+ + + +R+L + ED G+Y+ ENE+G A A +L
Sbjct: 353 SVLWLRNAVPLISSQRLRLSRRA--LRVLSMGP---EDEGVYQCMAENEVGSAHAVVQL 406
Score = 53.6 bits (123), Expect = 5e-07
Identities = 38/140 (27%), Positives = 65/140 (46%), Gaps = 8/140 (5%)
Query: 46 TARLKIKQVTAEDEGTYTCEASNCLGK-AKSNACLVVYHTRRLSSPGRQMAPTFYTYPFN 104
+ L+I + EDEG Y C A N + + K++ RR ++ ++ +
Sbjct: 182 SGNLQIVNASQEDEGMYKCAAYNPVTQEVKTSGSSDRLRVRRSTAEAARII--YPPEAQT 239
Query: 105 KVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDV 164
+V +G+++ +C G P P +W KDGS +T + ++ L ID S ED
Sbjct: 240 IIVTKGQSLILECVASGIPPPRVTWAKDGSSVT-----GYNKTRFLLSNLLIDTTSEEDS 294
Query: 165 GIYRITVENELGRAEASARL 184
G YR +N +G+ A+ L
Sbjct: 295 GTYRCMADNGVGQPGAAVIL 314
>AY027658-1|AAK14795.1| 1114|Homo sapiens brother of CDO protein.
Length = 1114
Score = 63.7 bits (148), Expect = 5e-10
Identities = 46/179 (25%), Positives = 78/179 (43%), Gaps = 17/179 (9%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G ++ EC +G P P + W + + L I + ED GTY C
Sbjct: 245 GQSLILECVASGIPPPRVTWAKDGSSVTGYNKTRFLLSN----LLIDTTSEEDSGTYRCM 300
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A N +G+ A +++Y+ + P M + P+ G++ C V+GNP P
Sbjct: 301 ADNGVGQP--GAAVILYNVQVFEPPEVTMELSQLVIPW------GQSAKLTCEVRGNPPP 352
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
W ++ + S R+ + + +R+L + ED G+Y+ ENE+G A A +L
Sbjct: 353 SVLWLRNAVPLISSQRLRLSRRA--LRVLSMGP---EDEGVYQCMAENEVGSAHAVVQL 406
Score = 53.6 bits (123), Expect = 5e-07
Identities = 38/140 (27%), Positives = 65/140 (46%), Gaps = 8/140 (5%)
Query: 46 TARLKIKQVTAEDEGTYTCEASNCLGK-AKSNACLVVYHTRRLSSPGRQMAPTFYTYPFN 104
+ L+I + EDEG Y C A N + + K++ RR ++ ++ +
Sbjct: 182 SGNLQIVNASQEDEGMYKCAAYNPVTQEVKTSGSSDRLRVRRSTAEAARII--YPPEAQT 239
Query: 105 KVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDV 164
+V +G+++ +C G P P +W KDGS +T + ++ L ID S ED
Sbjct: 240 IIVTKGQSLILECVASGIPPPRVTWAKDGSSVT-----GYNKTRFLLSNLLIDTTSEEDS 294
Query: 165 GIYRITVENELGRAEASARL 184
G YR +N +G+ A+ L
Sbjct: 295 GTYRCMADNGVGQPGAAVIL 314
>AK090455-1|BAC03436.1| 931|Homo sapiens FLJ00376 protein protein.
Length = 931
Score = 63.7 bits (148), Expect = 5e-10
Identities = 46/179 (25%), Positives = 78/179 (43%), Gaps = 17/179 (9%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G ++ EC +G P P + W + + L I + ED GTY C
Sbjct: 62 GQSLILECVASGIPPPRVTWAKDGSSVTGYNKTRFLLSN----LLIDTTSEEDSGTYRCM 117
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A N +G+ A +++Y+ + P M + P+ G++ C V+GNP P
Sbjct: 118 ADNGVGQP--GAAVILYNVQVFEPPEVTMELSQLVIPW------GQSAKLTCEVRGNPPP 169
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
W ++ + S R+ + + +R+L + ED G+Y+ ENE+G A A +L
Sbjct: 170 SVLWLRNAVPLISSQRLRLSRRA--LRVLSMGP---EDEGVYQCMAENEVGSAHAVVQL 223
Score = 46.0 bits (104), Expect = 1e-04
Identities = 30/101 (29%), Positives = 46/101 (45%), Gaps = 8/101 (7%)
Query: 87 LSSPGRQMAPTFYTYPFNK---VVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARIT 143
L+ PG YP +V +G+++ +C G P P +W KDGS +T
Sbjct: 36 LAPPGSTAEAARIIYPPEAQTIIVTKGQSLILECVASGIPPPRVTWAKDGSSVT-----G 90
Query: 144 VKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARL 184
+ ++ L ID S ED G YR +N +G+ A+ L
Sbjct: 91 YNKTRFLLSNLLIDTTSEEDSGTYRCMADNGVGQPGAAVIL 131
>BX538319-1|CAD98093.1| 1290|Homo sapiens hypothetical protein
protein.
Length = 1290
Score = 62.9 bits (146), Expect = 8e-10
Identities = 56/192 (29%), Positives = 75/192 (39%), Gaps = 15/192 (7%)
Query: 8 TVEFECQVTGNPDPDIRWFHYA--EVIRDCADFESSYD---DGTARLKIKQVTAEDEGTY 62
TV F+C+ TGNP P I W ++ +SS T L I V D G Y
Sbjct: 2 TVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYY 61
Query: 63 TCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGN 122
C+ N G + A L V P P P N+ V C G+
Sbjct: 62 ICQTLNVAGSIITKAYLEVTDVIADRPP-----PVIRQGPVNQTVAVDGTFVLSCVATGS 116
Query: 123 PSPWASWDKDGSII-TPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEAS 181
P P W KDG ++ T +RI K+ E +L+I + D G Y G A S
Sbjct: 117 PVPTILWRKDGVLVSTQDSRI--KQLEN--GVLQIRYAKLGDTGRYTCIASTPSGEATWS 172
Query: 182 ARLEVITRSGKF 193
A +EV + +F
Sbjct: 173 AYIEVQGKVNEF 184
>Y13901-1|CAA74200.1| 802|Homo sapiens fibroblast growth factor 4
protein.
Length = 802
Score = 62.5 bits (145), Expect = 1e-09
Identities = 58/199 (29%), Positives = 79/199 (39%), Gaps = 29/199 (14%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLK-------IKQVTAED 58
G+TV+F C GNP P IRW ++D F G RL+ ++ V D
Sbjct: 165 GNTVKFRCPAAGNPTPTIRW------LKDGQAFHGENRIGGIRLRHQHWSLVMESVVPSD 218
Query: 59 EGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCA 118
GTYTC N +G + N L V SP R + P N G +V C
Sbjct: 219 RGTYTCLVENAVGSIRYNYLLDVLE----RSPHRPILQA--GLPANTTAVVGSDVELLCK 272
Query: 119 VKGNPSPWASWDK----DGSII----TPSARI--TVKEKEEIMRILEIDEVSIEDVGIYR 168
V + P W K +GS P ++ T + +L + VS ED G Y
Sbjct: 273 VYSDAQPHIQWLKHIVINGSSFGADGFPYVQVLKTADINSSEVEVLYLRNVSAEDAGEYT 332
Query: 169 ITVENELGRAEASARLEVI 187
N +G + SA L V+
Sbjct: 333 CLAGNSIGLSYQSAWLTVL 351
Score = 46.8 bits (106), Expect = 6e-05
Identities = 33/103 (32%), Positives = 44/103 (42%), Gaps = 6/103 (5%)
Query: 93 QMAPTFYTYPFNK-----VVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEK 147
Q AP ++T+P V G V F+C GNP+P W KDG RI
Sbjct: 144 QQAP-YWTHPQRMEKKLHAVPAGNTVKFRCPAAGNPTPTIRWLKDGQAFHGENRIGGIRL 202
Query: 148 EEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVITRS 190
L ++ V D G Y VEN +G + L+V+ RS
Sbjct: 203 RHQHWSLVMESVVPSDRGTYTCLVENAVGSIRYNYLLDVLERS 245
>X61656-1|CAA43837.1| 1354|Homo sapiens membrane protein protein.
Length = 1354
Score = 62.5 bits (145), Expect = 1e-09
Identities = 30/76 (39%), Positives = 42/76 (55%), Gaps = 2/76 (2%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+++E C +GNP P I WF E + + D DG L I++V EDEG YTC+
Sbjct: 679 GESIEVSCTASGNPPPQIMWFKDNETLVE--DSGIVLKDGNRNLTIRRVRKEDEGLYTCQ 736
Query: 66 ASNCLGKAKSNACLVV 81
A + LG AK A ++
Sbjct: 737 ACSVLGCAKVEAFFII 752
Score = 58.4 bits (135), Expect = 2e-08
Identities = 41/134 (30%), Positives = 62/134 (46%), Gaps = 10/134 (7%)
Query: 49 LKIKQVTAEDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVE 108
+++K + +D+G Y C A + K K C+V R+L+ R +APT N+
Sbjct: 625 MELKNASLQDQGDYVCLAQD--RKTKKRHCVV----RQLTVLER-VAPTITGNLENQTTS 677
Query: 109 EGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYR 168
GE++ C GNP P W KD + + I +K+ R L I V ED G+Y
Sbjct: 678 IGESIEVSCTASGNPPPQIMWFKDNETLVEDSGIVLKDGN---RNLTIRRVRKEDEGLYT 734
Query: 169 ITVENELGRAEASA 182
+ LG A+ A
Sbjct: 735 CQACSVLGCAKVEA 748
Score = 44.0 bits (99), Expect = 4e-04
Identities = 42/135 (31%), Positives = 57/135 (42%), Gaps = 18/135 (13%)
Query: 49 LKIKQVTAEDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVE 108
L I VT D+G YTC AS+ L K N+ V H + + G M +VE
Sbjct: 290 LTIDGVTRSDQGLYTCAASSGL-MTKKNSTFVRVHEKPFVAFGSGM---------ESLVE 339
Query: 109 E--GENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
GE V G P P W K+G I + T+K +L I EVS D G
Sbjct: 340 ATVGERVRIPAKYLGYPPPEIKWYKNG--IPLESNHTIKAG----HVLTIMEVSERDTGN 393
Query: 167 YRITVENELGRAEAS 181
Y + + N + + + S
Sbjct: 394 YTVILTNPISKEKQS 408
Score = 32.7 bits (71), Expect = 1.0
Identities = 23/80 (28%), Positives = 37/80 (46%), Gaps = 9/80 (11%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTAR-LKIKQVTAEDEGTYTC 64
G+ V + G P P+I+W+ ++ ES++ L I +V+ D G YT
Sbjct: 343 GERVRIPAKYLGYPPPEIKWY------KNGIPLESNHTIKAGHVLTIMEVSERDTGNYTV 396
Query: 65 EASNCLGKAKSN--ACLVVY 82
+N + K K + LVVY
Sbjct: 397 ILTNPISKEKQSHVVSLVVY 416
>L04947-1|AAA59459.1| 1354|Homo sapiens receptor tyrosine kinase
protein.
Length = 1354
Score = 62.5 bits (145), Expect = 1e-09
Identities = 30/76 (39%), Positives = 42/76 (55%), Gaps = 2/76 (2%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+++E C +GNP P I WF E + + D DG L I++V EDEG YTC+
Sbjct: 679 GESIEVSCTASGNPPPQIMWFKDNETLVE--DSGIVLKDGNRNLTIRRVRKEDEGLYTCQ 736
Query: 66 ASNCLGKAKSNACLVV 81
A + LG AK A ++
Sbjct: 737 ACSVLGCAKVEAFFII 752
Score = 58.4 bits (135), Expect = 2e-08
Identities = 41/134 (30%), Positives = 62/134 (46%), Gaps = 10/134 (7%)
Query: 49 LKIKQVTAEDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVE 108
+++K + +D+G Y C A + K K C+V R+L+ R +APT N+
Sbjct: 625 MELKNASLQDQGDYVCLAQD--RKTKKRHCVV----RQLTVLER-VAPTITGNLENQTTS 677
Query: 109 EGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYR 168
GE++ C GNP P W KD + + I +K+ R L I V ED G+Y
Sbjct: 678 IGESIEVSCTASGNPPPQIMWFKDNETLVEDSGIVLKDGN---RNLTIRRVRKEDEGLYT 734
Query: 169 ITVENELGRAEASA 182
+ LG A+ A
Sbjct: 735 CQACSVLGCAKVEA 748
Score = 44.0 bits (99), Expect = 4e-04
Identities = 42/135 (31%), Positives = 57/135 (42%), Gaps = 18/135 (13%)
Query: 49 LKIKQVTAEDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVE 108
L I VT D+G YTC AS+ L K N+ V H + + G M +VE
Sbjct: 290 LTIDGVTRSDQGLYTCAASSGL-MTKKNSTFVRVHEKPFVAFGSGM---------ESLVE 339
Query: 109 E--GENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
GE V G P P W K+G I + T+K +L I EVS D G
Sbjct: 340 ATVGERVRIPAKYLGYPPPEIKWYKNG--IPLESNHTIKAG----HVLTIMEVSERDTGN 393
Query: 167 YRITVENELGRAEAS 181
Y + + N + + + S
Sbjct: 394 YTVILTNPISKEKQS 408
Score = 32.7 bits (71), Expect = 1.0
Identities = 23/80 (28%), Positives = 37/80 (46%), Gaps = 9/80 (11%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTAR-LKIKQVTAEDEGTYTC 64
G+ V + G P P+I+W+ ++ ES++ L I +V+ D G YT
Sbjct: 343 GERVRIPAKYLGYPPPEIKWY------KNGIPLESNHTIKAGHVLTIMEVSERDTGNYTV 396
Query: 65 EASNCLGKAKSN--ACLVVY 82
+N + K K + LVVY
Sbjct: 397 ILTNPISKEKQSHVVSLVVY 416
>L03840-1|AAB59389.1| 802|Homo sapiens fibroblast growth factor
receptor 4 protein.
Length = 802
Score = 62.5 bits (145), Expect = 1e-09
Identities = 58/199 (29%), Positives = 79/199 (39%), Gaps = 29/199 (14%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLK-------IKQVTAED 58
G+TV+F C GNP P IRW ++D F G RL+ ++ V D
Sbjct: 165 GNTVKFRCPAAGNPTPTIRW------LKDGQAFHGENRIGGIRLRHQHWSLVMESVVPSD 218
Query: 59 EGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCA 118
GTYTC N +G + N L V SP R + P N G +V C
Sbjct: 219 RGTYTCLVENAVGSIRYNYLLDVLE----RSPHRPILQA--GLPANTTAVVGSDVELLCK 272
Query: 119 VKGNPSPWASWDK----DGSII----TPSARI--TVKEKEEIMRILEIDEVSIEDVGIYR 168
V + P W K +GS P ++ T + +L + VS ED G Y
Sbjct: 273 VYSDAQPHIQWLKHIVINGSSFGADGFPYVQVLKTADINSSEVEVLYLRNVSAEDAGEYT 332
Query: 169 ITVENELGRAEASARLEVI 187
N +G + SA L V+
Sbjct: 333 CLAGNSIGLSYQSAWLTVL 351
Score = 46.8 bits (106), Expect = 6e-05
Identities = 33/103 (32%), Positives = 44/103 (42%), Gaps = 6/103 (5%)
Query: 93 QMAPTFYTYPFNK-----VVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEK 147
Q AP ++T+P V G V F+C GNP+P W KDG RI
Sbjct: 144 QQAP-YWTHPQRMEKKLHAVPAGNTVKFRCPAAGNPTPTIRWLKDGQAFHGENRIGGIRL 202
Query: 148 EEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVITRS 190
L ++ V D G Y VEN +G + L+V+ RS
Sbjct: 203 RHQHWSLVMESVVPSDRGTYTCLVENAVGSIRYNYLLDVLERS 245
>EF571596-1|ABQ01235.1| 802|Homo sapiens fibroblast growth factor
receptor 4 protein.
Length = 802
Score = 62.5 bits (145), Expect = 1e-09
Identities = 58/199 (29%), Positives = 79/199 (39%), Gaps = 29/199 (14%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLK-------IKQVTAED 58
G+TV+F C GNP P IRW ++D F G RL+ ++ V D
Sbjct: 165 GNTVKFRCPAAGNPTPTIRW------LKDGQAFHGENRIGGIRLRHQHWSLVMESVVPSD 218
Query: 59 EGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCA 118
GTYTC N +G + N L V SP R + P N G +V C
Sbjct: 219 RGTYTCLVENAVGSIRYNYLLDVLE----RSPHRPILQA--GLPANTTAVVGSDVELLCK 272
Query: 119 VKGNPSPWASWDK----DGSII----TPSARI--TVKEKEEIMRILEIDEVSIEDVGIYR 168
V + P W K +GS P ++ T + +L + VS ED G Y
Sbjct: 273 VYSDAQPHIQWLKHIVINGSSFGADGFPYVQVLKTADINSSEVEVLYLRNVSAEDAGEYT 332
Query: 169 ITVENELGRAEASARLEVI 187
N +G + SA L V+
Sbjct: 333 CLAGNSIGLSYQSAWLTVL 351
Score = 46.8 bits (106), Expect = 6e-05
Identities = 33/103 (32%), Positives = 44/103 (42%), Gaps = 6/103 (5%)
Query: 93 QMAPTFYTYPFNK-----VVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEK 147
Q AP ++T+P V G V F+C GNP+P W KDG RI
Sbjct: 144 QQAP-YWTHPQRMEKKLHAVPAGNTVKFRCPAAGNPTPTIRWLKDGQAFHGENRIGGIRL 202
Query: 148 EEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVITRS 190
L ++ V D G Y VEN +G + L+V+ RS
Sbjct: 203 RHQHWSLVMESVVPSDRGTYTCLVENAVGSIRYNYLLDVLERS 245
>EF063638-1|ABO42328.1| 1896|Homo sapiens obscurin-like 1 isoform A
protein.
Length = 1896
Score = 62.5 bits (145), Expect = 1e-09
Identities = 54/201 (26%), Positives = 75/201 (37%), Gaps = 20/201 (9%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G E +C V G P P + W + + D L + D G Y C
Sbjct: 26 GAEAELKCVVLGEPPPVVVWEKGGQQLAASERLSFPADGAEHGLLLTAALPTDAGVYVCR 85
Query: 66 ASNCLGKAKSNACLVVYHT-----------RRLSSPGR-QMAPTFYTYPFNKVVEEGENV 113
A N G+A + A + V R L SPG + AP F T P ++ V G V
Sbjct: 86 ARNAAGEAYAAAAVTVLEPPASDPELQPAERPLPSPGSGEGAPVFLTGPRSQWVLRGAEV 145
Query: 114 TFKCAVKGNPSPWASWDKDGSI---ITPSARITV-----KEKEEIMRILEIDEVSIEDVG 165
C G P P W+KDG + S+ + ++ L I + D G
Sbjct: 146 VLTCRAGGLPEPTLYWEKDGMALDEVWDSSHFALQPGRAEDGPGASLALRILAARLPDSG 205
Query: 166 IYRITVENELGRAEASARLEV 186
+Y N G A+A A L+V
Sbjct: 206 VYVCHARNAHGHAQAGALLQV 226
Score = 61.3 bits (142), Expect = 3e-09
Identities = 48/195 (24%), Positives = 76/195 (38%), Gaps = 14/195 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYA---EVIRDCADFE---SSYDDG---TARLKIKQVTA 56
G V C+ G P+P + W + + D + F +DG + L+I
Sbjct: 142 GAEVVLTCRAGGLPEPTLYWEKDGMALDEVWDSSHFALQPGRAEDGPGASLALRILAARL 201
Query: 57 EDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKV-----VEEGE 111
D G Y C A N G A++ A L V+ AP P V EG+
Sbjct: 202 PDSGVYVCHARNAHGHAQAGALLQVHQPPESPPADPDEAPAPVVEPLKCAPKTFWVNEGK 261
Query: 112 NVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITV 171
+ F+C V G P P W +G + P R + + +L++ +D G+Y
Sbjct: 262 HAKFRCYVMGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFVLKVLYCQAKDRGLYVCAA 321
Query: 172 ENELGRAEASARLEV 186
N G+ ++ +L V
Sbjct: 322 RNSAGQTLSAVQLHV 336
Score = 48.4 bits (110), Expect = 2e-05
Identities = 42/165 (25%), Positives = 66/165 (40%), Gaps = 15/165 (9%)
Query: 5 DGDTVEFECQVTGNPDPDIRW-FHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYT 63
+G +F C V G P+P+I W + ++ D DG LK+ A+D G Y
Sbjct: 259 EGKHAKFRCYVMGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFVLKVLYCQAKDRGLYV 318
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENV-TFKCAVKGN 122
C A N G+ S L V R +T P V + +C V +
Sbjct: 319 CAARNSAGQTLSAVQLHVKEPR-----------LRFTRPLQDVEGREHGIAVLECKVPNS 367
Query: 123 PSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIY 167
P A W ++ + P + E+ + R++ I + +D GIY
Sbjct: 368 RIPTA-WFREDQRLLPCRKYEQIEEGTVRRLI-IHRLKADDDGIY 410
Score = 45.6 bits (103), Expect = 1e-04
Identities = 44/184 (23%), Positives = 73/184 (39%), Gaps = 20/184 (10%)
Query: 3 SCDGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTY 62
S G +E ++G P +RW+ E + + L+++ + D G Y
Sbjct: 1281 STPGGDLELVVHLSG-PGGPVRWYKDGERLASQGRVQLEQAGARQVLRVQGARSGDAGEY 1339
Query: 63 TCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGN 122
C+A S LV L ++ P V EG++ TF+C V
Sbjct: 1340 LCDAPQ-----DSRIFLVSVEEPLLVKLVSELTPL--------TVHEGDDATFRCEV-SP 1385
Query: 123 PSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASA 182
P +W ++G+++TP ++ + + RIL + + D G TV G SA
Sbjct: 1386 PDADVTWLRNGAVVTPGPQVEMAQNGS-SRILTLRGCQLGDAG----TVTLRAGSTATSA 1440
Query: 183 RLEV 186
RL V
Sbjct: 1441 RLHV 1444
Score = 45.2 bits (102), Expect = 2e-04
Identities = 34/112 (30%), Positives = 53/112 (47%), Gaps = 7/112 (6%)
Query: 92 RQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIM 151
R++ T P + V EG+ TF+C + + +W+KDG+ +TPS R+ + +
Sbjct: 1625 REVPVTIVRGPHDLEVTEGDTATFECELSQALAD-VTWEKDGNALTPSPRLRL-QALGTR 1682
Query: 152 RILEIDEVSIEDVGIYRITVENELGRAEAS-ARLEVITRSGKFYGGLRAYSA 202
R+L++ D G Y V G A A RL V R+ LR+ SA
Sbjct: 1683 RLLQLRRCGPSDAGTYSCAV----GTARAGPVRLTVRERTVAVLSELRSVSA 1730
Score = 44.0 bits (99), Expect = 4e-04
Identities = 28/102 (27%), Positives = 41/102 (40%), Gaps = 1/102 (0%)
Query: 86 RLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVK 145
+ SS + P F +P V G KC V G P P W+K G + S R++
Sbjct: 2 KASSGDQGSPPCFLRFPRPVRVVSGAEAELKCVVLGEPPPVVVWEKGGQQLAASERLSFP 61
Query: 146 EKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVI 187
+L + D G+Y N G A A+A + V+
Sbjct: 62 ADGAEHGLL-LTAALPTDAGVYVCRARNAAGEAYAAAAVTVL 102
Score = 39.5 bits (88), Expect = 0.009
Identities = 43/174 (24%), Positives = 72/174 (41%), Gaps = 27/174 (15%)
Query: 7 DTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGT-ARLKIKQVTAEDEGTYTCE 65
+ V C+V D +RW+ + + + +DF ++G RL + D G + C
Sbjct: 823 ECVMLACEVD-REDAPVRWYKDGQEVEE-SDFVVLENEGPHRRLVLPATQPSDGGEFQCV 880
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEG---ENVTFKCAVKGN 122
A + C Y T ++ ++ YP KV E V C +
Sbjct: 881 AGD--------EC--AYFTVTITD-----VSSWIVYPSGKVYVAAVRLERVVLTCELC-- 923
Query: 123 PSPWAS--WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENE 174
PWA W KDG + S + + +KE+ +R L + V +ED G Y +++E
Sbjct: 924 -RPWAEVRWTKDGEEVVESPALLL-QKEDTVRRLVLPAVQLEDSGEYLCEIDDE 975
Score = 35.1 bits (77), Expect = 0.19
Identities = 17/54 (31%), Positives = 27/54 (50%), Gaps = 1/54 (1%)
Query: 12 ECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
EC+V + P WF + + C +E + RL I ++ A+D+G Y CE
Sbjct: 361 ECKVPNSRIPTA-WFREDQRLLPCRKYEQIEEGTVRRLIIHRLKADDDGIYLCE 413
>EF063637-1|ABO42327.1| 1544|Homo sapiens obscurin-like 1 isoform C
protein.
Length = 1544
Score = 62.5 bits (145), Expect = 1e-09
Identities = 54/201 (26%), Positives = 75/201 (37%), Gaps = 20/201 (9%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G E +C V G P P + W + + D L + D G Y C
Sbjct: 26 GAEAELKCVVLGEPPPVVVWEKGGQQLAASERLSFPADGAEHGLLLTAALPTDAGVYVCR 85
Query: 66 ASNCLGKAKSNACLVVYHT-----------RRLSSPGR-QMAPTFYTYPFNKVVEEGENV 113
A N G+A + A + V R L SPG + AP F T P ++ V G V
Sbjct: 86 ARNAAGEAYAAAAVTVLEPPASDPELQPAERPLPSPGSGEGAPVFLTGPRSQWVLRGAEV 145
Query: 114 TFKCAVKGNPSPWASWDKDGSI---ITPSARITV-----KEKEEIMRILEIDEVSIEDVG 165
C G P P W+KDG + S+ + ++ L I + D G
Sbjct: 146 VLTCRAGGLPEPTLYWEKDGMALDEVWDSSHFALQPGRAEDGPGASLALRILAARLPDSG 205
Query: 166 IYRITVENELGRAEASARLEV 186
+Y N G A+A A L+V
Sbjct: 206 VYVCHARNAHGHAQAGALLQV 226
Score = 61.3 bits (142), Expect = 3e-09
Identities = 48/195 (24%), Positives = 76/195 (38%), Gaps = 14/195 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYA---EVIRDCADFE---SSYDDG---TARLKIKQVTA 56
G V C+ G P+P + W + + D + F +DG + L+I
Sbjct: 142 GAEVVLTCRAGGLPEPTLYWEKDGMALDEVWDSSHFALQPGRAEDGPGASLALRILAARL 201
Query: 57 EDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKV-----VEEGE 111
D G Y C A N G A++ A L V+ AP P V EG+
Sbjct: 202 PDSGVYVCHARNAHGHAQAGALLQVHQPPESPPADPDEAPAPVVEPLKCAPKTFWVNEGK 261
Query: 112 NVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITV 171
+ F+C V G P P W +G + P R + + +L++ +D G+Y
Sbjct: 262 HAKFRCYVMGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFVLKVLYCQAKDRGLYVCAA 321
Query: 172 ENELGRAEASARLEV 186
N G+ ++ +L V
Sbjct: 322 RNSAGQTLSAVQLHV 336
Score = 48.4 bits (110), Expect = 2e-05
Identities = 42/165 (25%), Positives = 66/165 (40%), Gaps = 15/165 (9%)
Query: 5 DGDTVEFECQVTGNPDPDIRW-FHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYT 63
+G +F C V G P+P+I W + ++ D DG LK+ A+D G Y
Sbjct: 259 EGKHAKFRCYVMGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFVLKVLYCQAKDRGLYV 318
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENV-TFKCAVKGN 122
C A N G+ S L V R +T P V + +C V +
Sbjct: 319 CAARNSAGQTLSAVQLHVKEPR-----------LRFTRPLQDVEGREHGIAVLECKVPNS 367
Query: 123 PSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIY 167
P A W ++ + P + E+ + R++ I + +D GIY
Sbjct: 368 RIPTA-WFREDQRLLPCRKYEQIEEGTVRRLI-IHRLKADDDGIY 410
Score = 45.6 bits (103), Expect = 1e-04
Identities = 44/184 (23%), Positives = 73/184 (39%), Gaps = 20/184 (10%)
Query: 3 SCDGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTY 62
S G +E ++G P +RW+ E + + L+++ + D G Y
Sbjct: 1282 STPGGDLELVVHLSG-PGGPVRWYKDGERLASQGRVQLEQAGARQVLRVQGARSGDAGEY 1340
Query: 63 TCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGN 122
C+A S LV L ++ P V EG++ TF+C V
Sbjct: 1341 LCDAPQ-----DSRIFLVSVEEPLLVKLVSELTPL--------TVHEGDDATFRCEV-SP 1386
Query: 123 PSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASA 182
P +W ++G+++TP ++ + + RIL + + D G TV G SA
Sbjct: 1387 PDADVTWLRNGAVVTPGPQVEMAQNGS-SRILTLRGCQLGDAG----TVTLRAGSTATSA 1441
Query: 183 RLEV 186
RL V
Sbjct: 1442 RLHV 1445
Score = 44.0 bits (99), Expect = 4e-04
Identities = 28/102 (27%), Positives = 41/102 (40%), Gaps = 1/102 (0%)
Query: 86 RLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVK 145
+ SS + P F +P V G KC V G P P W+K G + S R++
Sbjct: 2 KASSGDQGSPPCFLRFPRPVRVVSGAEAELKCVVLGEPPPVVVWEKGGQQLAASERLSFP 61
Query: 146 EKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVI 187
+L + D G+Y N G A A+A + V+
Sbjct: 62 ADGAEHGLL-LTAALPTDAGVYVCRARNAAGEAYAAAAVTVL 102
Score = 39.5 bits (88), Expect = 0.009
Identities = 43/174 (24%), Positives = 72/174 (41%), Gaps = 27/174 (15%)
Query: 7 DTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGT-ARLKIKQVTAEDEGTYTCE 65
+ V C+V D +RW+ + + + +DF ++G RL + D G + C
Sbjct: 824 ECVMLACEVD-REDAPVRWYKDGQEVEE-SDFVVLENEGPHRRLVLPATQPSDGGEFQCV 881
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEG---ENVTFKCAVKGN 122
A + C Y T ++ ++ YP KV E V C +
Sbjct: 882 AGD--------EC--AYFTVTITD-----VSSWIVYPSGKVYVAAVRLERVVLTCELC-- 924
Query: 123 PSPWAS--WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENE 174
PWA W KDG + S + + +KE+ +R L + V +ED G Y +++E
Sbjct: 925 -RPWAEVRWTKDGEEVVESPALLL-QKEDTVRRLVLPAVQLEDSGEYLCEIDDE 976
Score = 35.1 bits (77), Expect = 0.19
Identities = 17/54 (31%), Positives = 27/54 (50%), Gaps = 1/54 (1%)
Query: 12 ECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
EC+V + P WF + + C +E + RL I ++ A+D+G Y CE
Sbjct: 361 ECKVPNSRIPTA-WFREDQRLLPCRKYEQIEEGTVRRLIIHRLKADDDGIYLCE 413
>BC131822-1|AAI31823.1| 1356|Homo sapiens kinase insert domain
receptor (a type III receptor tyrosine kinase) protein.
Length = 1356
Score = 62.5 bits (145), Expect = 1e-09
Identities = 30/76 (39%), Positives = 42/76 (55%), Gaps = 2/76 (2%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+++E C +GNP P I WF E + + D DG L I++V EDEG YTC+
Sbjct: 681 GESIEVSCTASGNPPPQIMWFKDNETLVE--DSGIVLKDGNRNLTIRRVRKEDEGLYTCQ 738
Query: 66 ASNCLGKAKSNACLVV 81
A + LG AK A ++
Sbjct: 739 ACSVLGCAKVEAFFII 754
Score = 58.4 bits (135), Expect = 2e-08
Identities = 41/134 (30%), Positives = 62/134 (46%), Gaps = 10/134 (7%)
Query: 49 LKIKQVTAEDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVE 108
+++K + +D+G Y C A + K K C+V R+L+ R +APT N+
Sbjct: 627 MELKNASLQDQGDYVCLAQD--RKTKKRHCVV----RQLTVLER-VAPTITGNLENQTTS 679
Query: 109 EGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYR 168
GE++ C GNP P W KD + + I +K+ R L I V ED G+Y
Sbjct: 680 IGESIEVSCTASGNPPPQIMWFKDNETLVEDSGIVLKDGN---RNLTIRRVRKEDEGLYT 736
Query: 169 ITVENELGRAEASA 182
+ LG A+ A
Sbjct: 737 CQACSVLGCAKVEA 750
Score = 43.6 bits (98), Expect = 6e-04
Identities = 41/135 (30%), Positives = 57/135 (42%), Gaps = 18/135 (13%)
Query: 49 LKIKQVTAEDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVE 108
L I +T D+G YTC AS+ L K N+ V H + + G M +VE
Sbjct: 292 LTIDGITRSDQGLYTCAASSGL-MTKKNSTFVRVHEKPFVAFGSGM---------ESLVE 341
Query: 109 E--GENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
GE V G P P W K+G I + T+K +L I EVS D G
Sbjct: 342 ATVGERVRIPAKYLGYPPPEIKWYKNG--IPLESNHTIKAG----HVLTIMEVSERDTGN 395
Query: 167 YRITVENELGRAEAS 181
Y + + N + + + S
Sbjct: 396 YTVILTNPISKEKQS 410
Score = 32.7 bits (71), Expect = 1.0
Identities = 23/80 (28%), Positives = 37/80 (46%), Gaps = 9/80 (11%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTAR-LKIKQVTAEDEGTYTC 64
G+ V + G P P+I+W+ ++ ES++ L I +V+ D G YT
Sbjct: 345 GERVRIPAKYLGYPPPEIKWY------KNGIPLESNHTIKAGHVLTIMEVSERDTGNYTV 398
Query: 65 EASNCLGKAKSN--ACLVVY 82
+N + K K + LVVY
Sbjct: 399 ILTNPISKEKQSHVVSLVVY 418
>BC011847-1|AAH11847.1| 802|Homo sapiens fibroblast growth factor
receptor 4 protein.
Length = 802
Score = 62.5 bits (145), Expect = 1e-09
Identities = 58/199 (29%), Positives = 79/199 (39%), Gaps = 29/199 (14%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLK-------IKQVTAED 58
G+TV+F C GNP P IRW ++D F G RL+ ++ V D
Sbjct: 165 GNTVKFRCPAAGNPTPTIRW------LKDGQAFHGENRIGGIRLRHQHWSLVMESVVPSD 218
Query: 59 EGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCA 118
GTYTC N +G + N L V SP R + P N G +V C
Sbjct: 219 RGTYTCLVENAVGSIRYNYLLDVLE----RSPHRPILQA--GLPANTTAVVGSDVELLCK 272
Query: 119 VKGNPSPWASWDK----DGSII----TPSARI--TVKEKEEIMRILEIDEVSIEDVGIYR 168
V + P W K +GS P ++ T + +L + VS ED G Y
Sbjct: 273 VYSDAQPHIQWLKHIVINGSSFGADGFPYVQVLKTADINSSEVEVLYLRNVSAEDAGEYT 332
Query: 169 ITVENELGRAEASARLEVI 187
N +G + SA L V+
Sbjct: 333 CLAGNSIGLSYQSAWLTVL 351
Score = 46.8 bits (106), Expect = 6e-05
Identities = 33/103 (32%), Positives = 44/103 (42%), Gaps = 6/103 (5%)
Query: 93 QMAPTFYTYPFNK-----VVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEK 147
Q AP ++T+P V G V F+C GNP+P W KDG RI
Sbjct: 144 QQAP-YWTHPQRMEKKLHAVPAGNTVKFRCPAAGNPTPTIRWLKDGQAFHGENRIGGIRL 202
Query: 148 EEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVITRS 190
L ++ V D G Y VEN +G + L+V+ RS
Sbjct: 203 RHQHWSLVMESVVPSDRGTYTCLVENAVGSIRYNYLLDVLERS 245
>BC007201-1|AAH07201.1| 1044|Homo sapiens OBSL1 protein protein.
Length = 1044
Score = 62.5 bits (145), Expect = 1e-09
Identities = 54/201 (26%), Positives = 75/201 (37%), Gaps = 20/201 (9%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G E +C V G P P + W + + D L + D G Y C
Sbjct: 45 GAEAELKCVVLGEPPPVVVWEKGGQQLAASERLSFPADGAEHGLLLTAALPTDAGVYVCR 104
Query: 66 ASNCLGKAKSNACLVVYHT-----------RRLSSPGR-QMAPTFYTYPFNKVVEEGENV 113
A N G+A + A + V R L SPG + AP F T P ++ V G V
Sbjct: 105 ARNAAGEAYAAAAVTVLEPPASDPELQPAERPLPSPGSGEGAPVFLTGPRSQWVLRGAEV 164
Query: 114 TFKCAVKGNPSPWASWDKDGSI---ITPSARITV-----KEKEEIMRILEIDEVSIEDVG 165
C G P P W+KDG + S+ + ++ L I + D G
Sbjct: 165 VLTCRAGGLPEPTLYWEKDGMALDEVWDSSHFALQPGRAEDGPGASLALRILAARLPDSG 224
Query: 166 IYRITVENELGRAEASARLEV 186
+Y N G A+A A L+V
Sbjct: 225 VYVCHARNAHGHAQAGALLQV 245
Score = 61.3 bits (142), Expect = 3e-09
Identities = 48/195 (24%), Positives = 76/195 (38%), Gaps = 14/195 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYA---EVIRDCADFE---SSYDDG---TARLKIKQVTA 56
G V C+ G P+P + W + + D + F +DG + L+I
Sbjct: 161 GAEVVLTCRAGGLPEPTLYWEKDGMALDEVWDSSHFALQPGRAEDGPGASLALRILAARL 220
Query: 57 EDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKV-----VEEGE 111
D G Y C A N G A++ A L V+ AP P V EG+
Sbjct: 221 PDSGVYVCHARNAHGHAQAGALLQVHQPPESPPADPDEAPAPVVEPLKCAPKTFWVNEGK 280
Query: 112 NVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITV 171
+ F+C V G P P W +G + P R + + +L++ +D G+Y
Sbjct: 281 HAKFRCYVMGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFVLKVLYCQAKDRGLYVCAA 340
Query: 172 ENELGRAEASARLEV 186
N G+ ++ +L V
Sbjct: 341 RNSAGQTLSAVQLHV 355
Score = 48.4 bits (110), Expect = 2e-05
Identities = 42/165 (25%), Positives = 66/165 (40%), Gaps = 15/165 (9%)
Query: 5 DGDTVEFECQVTGNPDPDIRW-FHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYT 63
+G +F C V G P+P+I W + ++ D DG LK+ A+D G Y
Sbjct: 278 EGKHAKFRCYVMGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFVLKVLYCQAKDRGLYV 337
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENV-TFKCAVKGN 122
C A N G+ S L V R +T P V + +C V +
Sbjct: 338 CAARNSAGQTLSAVQLHVKEPR-----------LRFTRPLQDVEGREHGIAVLECKVPNS 386
Query: 123 PSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIY 167
P A W ++ + P + E+ + R++ I + +D GIY
Sbjct: 387 RIPTA-WFREDQRLLPCRKYEQIEEGTVRRLI-IHRLKADDDGIY 429
Score = 44.0 bits (99), Expect = 4e-04
Identities = 28/102 (27%), Positives = 41/102 (40%), Gaps = 1/102 (0%)
Query: 86 RLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVK 145
+ SS + P F +P V G KC V G P P W+K G + S R++
Sbjct: 21 KASSGDQGSPPCFLRFPRPVRVVSGAEAELKCVVLGEPPPVVVWEKGGQQLAASERLSFP 80
Query: 146 EKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVI 187
+L + D G+Y N G A A+A + V+
Sbjct: 81 ADGAEHGLL-LTAALPTDAGVYVCRARNAAGEAYAAAAVTVL 121
Score = 39.5 bits (88), Expect = 0.009
Identities = 43/174 (24%), Positives = 72/174 (41%), Gaps = 27/174 (15%)
Query: 7 DTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGT-ARLKIKQVTAEDEGTYTCE 65
+ V C+V D +RW+ + + + +DF ++G RL + D G + C
Sbjct: 842 ECVMLACEVD-REDAPVRWYKDGQEVEE-SDFVVLENEGPHRRLVLPATQPSDGGEFQCV 899
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEG---ENVTFKCAVKGN 122
A + C Y T ++ ++ YP KV E V C +
Sbjct: 900 AGD--------EC--AYFTVTITD-----VSSWIVYPSGKVYVAAVRLERVVLTCELC-- 942
Query: 123 PSPWAS--WDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENE 174
PWA W KDG + S + + +KE+ +R L + V +ED G Y +++E
Sbjct: 943 -RPWAEVRWTKDGEEVVESPALLL-QKEDTVRRLVLPAVQLEDSGEYLCEIDDE 994
Score = 35.1 bits (77), Expect = 0.19
Identities = 17/54 (31%), Positives = 27/54 (50%), Gaps = 1/54 (1%)
Query: 12 ECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
EC+V + P WF + + C +E + RL I ++ A+D+G Y CE
Sbjct: 380 ECKVPNSRIPTA-WFREDQRLLPCRKYEQIEEGTVRRLIIHRLKADDDGIYLCE 432
>AJ314906-1|CAC85753.1| 1040|Homo sapiens obscurin protein.
Length = 1040
Score = 62.5 bits (145), Expect = 1e-09
Identities = 32/92 (34%), Positives = 45/92 (48%)
Query: 95 APTFYTYPFNKVVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRIL 154
AP F T N+ V++G V+F C V G P P W KDG ++ + E ++ L
Sbjct: 696 APVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQL 755
Query: 155 EIDEVSIEDVGIYRITVENELGRAEASARLEV 186
I V D+G+YR EN +G + A L V
Sbjct: 756 IITAVVPADMGVYRCLAENSMGVSSTKAELRV 787
Score = 60.9 bits (141), Expect = 3e-09
Identities = 50/191 (26%), Positives = 81/191 (42%), Gaps = 17/191 (8%)
Query: 10 EFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNC 69
+F+ +V G P P + WF + + A + L+I VT ED G Y SN
Sbjct: 851 KFQLKVKGYPAPRLYWFKDGQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNA 910
Query: 70 LGKAKSNACLVVY-----HTRRLSSPGRQMAPTFYTYPFN-KVVEEGENVTFKCAVKGNP 123
+G A S+A L+V + S Q+ P F K V++G ++TF V+G P
Sbjct: 911 MGAAYSSARLLVRGPDEPEEKPASDVHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGRP 970
Query: 124 SPWASW---DKDGSII-----TPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENEL 175
P W + + ++ TP + ++ + +L++ + G Y N
Sbjct: 971 VPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLDVGR---QHQGTYTCIASNAA 1027
Query: 176 GRAEASARLEV 186
G+A SA L V
Sbjct: 1028 GQALCSASLHV 1038
Score = 52.0 bits (119), Expect = 2e-06
Identities = 28/78 (35%), Positives = 40/78 (51%), Gaps = 1/78 (1%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYD-DGTARLKIKQVTAEDEGTYT 63
DG V F+C VTG P P +RWF +++ + + + D G +L I V D G Y
Sbjct: 710 DGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQLIITAVVPADMGVYR 769
Query: 64 CEASNCLGKAKSNACLVV 81
C A N +G + + A L V
Sbjct: 770 CLAENSMGVSSTKAELRV 787
Score = 48.4 bits (110), Expect = 2e-05
Identities = 26/77 (33%), Positives = 33/77 (42%), Gaps = 1/77 (1%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFE-SSYDDGTARLKIKQVTAEDEGTYTC 64
GD + EC V D RW + D DGT L I + D G YTC
Sbjct: 483 GDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLGDGTCSLLITGLDRADAGCYTC 542
Query: 65 EASNCLGKAKSNACLVV 81
+ SN G+ +AC+VV
Sbjct: 543 QVSNKFGQVTHSACVVV 559
Score = 36.7 bits (81), Expect = 0.063
Identities = 25/82 (30%), Positives = 37/82 (45%), Gaps = 6/82 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRWF-HYAE-----VIRDCADFESSYDDGTARLKIKQVTAEDE 59
G ++ F +V G P P + W AE + D + + L + V + +
Sbjct: 957 GSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLDVGRQHQ 1016
Query: 60 GTYTCEASNCLGKAKSNACLVV 81
GTYTC ASN G+A +A L V
Sbjct: 1017 GTYTCIASNAAGQALCSASLHV 1038
Score = 30.7 bits (66), Expect = 4.2
Identities = 21/92 (22%), Positives = 36/92 (39%), Gaps = 1/92 (1%)
Query: 92 RQMAPTFYTYPFNKV-VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEI 150
+Q +++ F + G+ + +C V A W KDG +T + + +
Sbjct: 464 KQQEGPMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLGDG 523
Query: 151 MRILEIDEVSIEDVGIYRITVENELGRAEASA 182
L I + D G Y V N+ G+ SA
Sbjct: 524 TCSLLITGLDRADAGCYTCQVSNKFGQVTHSA 555
Score = 29.9 bits (64), Expect = 7.3
Identities = 19/59 (32%), Positives = 25/59 (42%), Gaps = 1/59 (1%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
G+ V E +V ++ W E I+ FE L IK TAED+G Y C
Sbjct: 209 GEDVSLELEVVAEAG-EVIWHKGMERIQPGGRFEVVSQGRQQMLVIKGFTAEDQGEYHC 266
>AF487555-1|AAM13666.1| 802|Homo sapiens fibroblast growth factor
receptor 4 protein.
Length = 802
Score = 62.5 bits (145), Expect = 1e-09
Identities = 58/199 (29%), Positives = 79/199 (39%), Gaps = 29/199 (14%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLK-------IKQVTAED 58
G+TV+F C GNP P IRW ++D F G RL+ ++ V D
Sbjct: 165 GNTVKFRCPAAGNPTPTIRW------LKDGQAFHGENRIGGIRLRHQHWSLVMESVVPSD 218
Query: 59 EGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCA 118
GTYTC N +G + N L V SP R + P N G +V C
Sbjct: 219 RGTYTCLVENAVGSIRYNYLLDVLE----RSPHRPILQA--GLPANTTAVVGSDVELLCK 272
Query: 119 VKGNPSPWASWDK----DGSII----TPSARI--TVKEKEEIMRILEIDEVSIEDVGIYR 168
V + P W K +GS P ++ T + +L + VS ED G Y
Sbjct: 273 VYSDAQPHIQWLKHIVINGSSFGADGFPYVQVLKTADINSSEVEVLYLRNVSAEDAGEYT 332
Query: 169 ITVENELGRAEASARLEVI 187
N +G + SA L V+
Sbjct: 333 CLAGNSIGLSYQSAWLTVL 351
Score = 46.8 bits (106), Expect = 6e-05
Identities = 33/103 (32%), Positives = 44/103 (42%), Gaps = 6/103 (5%)
Query: 93 QMAPTFYTYPFNK-----VVEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEK 147
Q AP ++T+P V G V F+C GNP+P W KDG RI
Sbjct: 144 QQAP-YWTHPQRMEKKLHAVPAGNTVKFRCPAAGNPTPTIRWLKDGQAFHGENRIGGIRL 202
Query: 148 EEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVITRS 190
L ++ V D G Y VEN +G + L+V+ RS
Sbjct: 203 RHQHWSLVMESVVPSDRGTYTCLVENAVGSIRYNYLLDVLERS 245
>AF245505-1|AAF86402.1| 2828|Homo sapiens adlican protein.
Length = 2828
Score = 62.5 bits (145), Expect = 1e-09
Identities = 53/192 (27%), Positives = 84/192 (43%), Gaps = 21/192 (10%)
Query: 2 LSCDGDTVEFECQVTGNPDPDIRWFHYAE--VIRDCADFESSYDDGTARLKIKQVTAEDE 59
++ + DTV F C+ TG P P + W + ++ + L I++V +D
Sbjct: 1865 VTAETDTV-FPCEATGKPKPFVTWTKVSTGALMTPNTRIQRFEVLKNGTLVIRKVQVQDR 1923
Query: 60 GTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAV 119
G Y C ASN G + +VV + + P Q+ + Y + V G+ + +C
Sbjct: 1924 GQYMCTASNLHGLDR----MVVLLSVTVQQP--QILASHYQ---DVTVYLGDTIAMECLA 1974
Query: 120 KGNPSPWASW----DKDGSIITP-SARITVKEKEEIMRILEIDEVSIEDVGIYRITVENE 174
KG P+P SW + ++P +RIT+ E R L I E S D G+Y+ N
Sbjct: 1975 KGTPAPQISWIFPDRRVWQTVSPVESRITLHEN----RTLSIKEASFSDRGVYKCVASNA 2030
Query: 175 LGRAEASARLEV 186
G + RL V
Sbjct: 2031 AGADSLAIRLHV 2042
Score = 52.8 bits (121), Expect = 9e-07
Identities = 50/185 (27%), Positives = 72/185 (38%), Gaps = 14/185 (7%)
Query: 6 GDTVEFECQVTGNPDPDIRW-FHYAEVIRDCADFESSYDDGTAR-LKIKQVTAEDEGTYT 63
GDT+ EC G P P I W F V + + ES R L IK+ + D G Y
Sbjct: 1965 GDTIAMECLAKGTPAPQISWIFPDRRVWQTVSPVESRITLHENRTLSIKEASFSDRGVYK 2024
Query: 64 CEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKV-VEEGENVTFKCAVKGN 122
C ASN G +++ + H L P + + + G ++ C K
Sbjct: 2025 CVASNAAG---ADSLAIRLHVAAL-------PPVIHQEKLENISLPPGLSIHIHCTAKAA 2074
Query: 123 PSPWASWD-KDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEAS 181
P P W DG+ I PS + L I ++ +D G Y N +G A +
Sbjct: 2075 PLPSVRWVLGDGTQIRPSQFLHGNLFVFPNGTLYIRNLAPKDSGRYECVAANLVGSARRT 2134
Query: 182 ARLEV 186
+L V
Sbjct: 2135 VQLNV 2139
Score = 52.4 bits (120), Expect = 1e-06
Identities = 53/194 (27%), Positives = 87/194 (44%), Gaps = 22/194 (11%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCA-DFESS---YDDGTARLKIKQVTAEDEGT 61
G T++ +C +G+P P I W ++ + D F+S + +GT L +K VT +D G
Sbjct: 2161 GGTLKLDCSASGDPWPRILWRLPSKRMIDALFSFDSRIKVFANGT--LVVKSVTDKDAGD 2218
Query: 62 YTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKG 121
Y C A N +G VV + P A + + V G ++ C G
Sbjct: 2219 YLCVARNKVGDD-----YVVLKVDVVMKP----AKIEHKEENDHKVFYGGDLKVDCVATG 2269
Query: 122 NPSPWASWD-KDGSIITP---SARITVKEKEEIM---RILEIDEVSIEDVGIYRITVENE 174
P+P SW DGS++ S + K ++ L +EV + + G Y EN+
Sbjct: 2270 LPNPEISWSLPDGSLVNSFMQSDDSGGRTKRYVVFNNGTLYFNEVGMREEGDYTCFAENQ 2329
Query: 175 LGRAEASARLEVIT 188
+G+ E R++V+T
Sbjct: 2330 VGKDEMRVRVKVVT 2343
Score = 50.4 bits (115), Expect = 5e-06
Identities = 51/202 (25%), Positives = 81/202 (40%), Gaps = 27/202 (13%)
Query: 6 GDTVEFECQVTGNPDPDIRW-FHYAEVIRDCADFESS---------YDDGTARLKIKQVT 55
G ++ +C TG P+P+I W ++ + S +++GT L +V
Sbjct: 2258 GGDLKVDCVATGLPNPEISWSLPDGSLVNSFMQSDDSGGRTKRYVVFNNGT--LYFNEVG 2315
Query: 56 AEDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTF 115
+EG YTC A N +GK + + V +++P T+ V G+ VT
Sbjct: 2316 MREEGDYTCFAENQVGKDEMRVRVKV-----VTAPATIRNKTYLAVQ----VPYGDVVTV 2366
Query: 116 KCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMR--ILEIDEVSIEDVGIYRITVEN 173
C KG P P +W + + P T EK +I + L I + D G Y V N
Sbjct: 2367 ACEAKGEPMPKVTWLSPTNKVIP----TSSEKYQIYQDGTLLIQKAQRSDSGNYTCLVRN 2422
Query: 174 ELGRAEASARLEVITRSGKFYG 195
G + + V + K G
Sbjct: 2423 SAGEDRKTVWIHVNVQPPKING 2444
Score = 48.8 bits (111), Expect = 1e-05
Identities = 34/135 (25%), Positives = 52/135 (38%), Gaps = 8/135 (5%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYA-EVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTC 64
GD V C+ G P P + W +VI ++ Y DGT L I++ D G YTC
Sbjct: 2361 GDVVTVACEAKGEPMPKVTWLSPTNKVIPTSSEKYQIYQDGT--LLIQKAQRSDSGNYTC 2418
Query: 65 EASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPS 124
N G+ + + V + P P T ++ G C +G P+
Sbjct: 2419 LVRNSAGEDRKTVWIHV----NVQPPKINGNPNPIT-TVREIAAGGSRKLIDCKAEGIPT 2473
Query: 125 PWASWDKDGSIITPS 139
P W ++ P+
Sbjct: 2474 PRVLWAFPEGVVLPA 2488
Score = 44.0 bits (99), Expect = 4e-04
Identities = 42/187 (22%), Positives = 69/187 (36%), Gaps = 10/187 (5%)
Query: 2 LSCDGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYD-DGTARLKIKQVTAEDEG 60
++ G +C+ G P P + W V+ + + G L I+ + D
Sbjct: 2455 IAAGGSRKLIDCKAEGIPTPRVLWAFPEGVVLPAPYYGNRITVHGNGSLDIRSLRKSDSV 2514
Query: 61 TYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVE-EGENVTFKCAV 119
C A N G+A+ L+V T + P + P F+ K+ G ++ C+
Sbjct: 2515 QLVCMARNEGGEAR----LIVQLT--VLEPMEK--PIFHDPISEKITAMAGHTISLNCSA 2566
Query: 120 KGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAE 179
G P+P W S + + + +L I +S D G YR N G E
Sbjct: 2567 AGTPTPSLVWVLPNGTDLQSGQQLQRFYHKADGMLHISGLSSVDAGAYRCVARNAAGHTE 2626
Query: 180 ASARLEV 186
L+V
Sbjct: 2627 RLVSLKV 2633
Score = 38.7 bits (86), Expect = 0.016
Identities = 38/151 (25%), Positives = 56/151 (37%), Gaps = 16/151 (10%)
Query: 40 SSYDDGTARLKIKQVTAEDEGTYTCEASNCLG-KAKSNACLVVYHTRRLSSPGRQMAPTF 98
S D+GT L +++ + D GTY C G S +V+ + R++S + P
Sbjct: 2689 SLLDNGT--LTVREASVFDRGTYVCRMETEYGPSVTSIPVIVIAYPPRITS---EPTPVI 2743
Query: 99 YTYPFNKVVEEGENVTFKCAVKGNPSPWASW---DKDGSIITPSARITVKEKEEIMRILE 155
YT P G V C G P +W DK AR+ L
Sbjct: 2744 YTRP-------GNTVKLNCMAMGIPKADITWELPDKSHLKAGVQARLYGNRFLHPQGSLT 2796
Query: 156 IDEVSIEDVGIYRITVENELGRAEASARLEV 186
I + D G Y+ +N LG + + V
Sbjct: 2797 IQHATQRDAGFYKCMAKNILGSDSKTTYIHV 2827
Score = 37.9 bits (84), Expect = 0.027
Identities = 46/195 (23%), Positives = 70/195 (35%), Gaps = 23/195 (11%)
Query: 5 DGDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTAR--------LKIKQVTA 56
+G + C V + P I W V+ D + ++ DD ++ L+IK +
Sbjct: 493 EGGPCQLSCNVKASESPSIFW-----VLPDGSILKAPMDDPDSKFSILSSGWLRIKSMEP 547
Query: 57 EDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFK 116
D G Y C+ + + +VY + SP Q A T K GE+VT
Sbjct: 548 SDSGLY-----QCIAQVRDEMDRMVYRV-LVQSPSTQPAEK-DTVTIGK--NPGESVTLP 598
Query: 117 CAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELG 176
C P SW I T L I +V + D G YR N+ G
Sbjct: 599 CNALAIPEAHLSWILPNRRIINDLANTSHVYMLPNGTLSIPKVQVSDSGYYRCVAVNQQG 658
Query: 177 RAEASARLEVITRSG 191
+ + +T+ G
Sbjct: 659 ADHFTVGI-TVTKKG 672
Score = 33.1 bits (72), Expect = 0.78
Identities = 21/81 (25%), Positives = 31/81 (38%), Gaps = 4/81 (4%)
Query: 6 GDTVEFECQVTGNPDPDIRWF----HYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGT 61
G+TV+ C G P DI W + + + + + L I+ T D G
Sbjct: 2748 GNTVKLNCMAMGIPKADITWELPDKSHLKAGVQARLYGNRFLHPQGSLTIQHATQRDAGF 2807
Query: 62 YTCEASNCLGKAKSNACLVVY 82
Y C A N LG + V+
Sbjct: 2808 YKCMAKNILGSDSKTTYIHVF 2828
>AF063658-1|AAC16450.1| 1356|Homo sapiens vascular endothelial
growth factor receptor 2 protein.
Length = 1356
Score = 62.5 bits (145), Expect = 1e-09
Identities = 30/76 (39%), Positives = 42/76 (55%), Gaps = 2/76 (2%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+++E C +GNP P I WF E + + D DG L I++V EDEG YTC+
Sbjct: 681 GESIEVSCTASGNPPPQIMWFKDNETLVE--DSGIVLKDGNRNLTIRRVRKEDEGLYTCQ 738
Query: 66 ASNCLGKAKSNACLVV 81
A + LG AK A ++
Sbjct: 739 ACSVLGCAKVEAFFII 754
Score = 58.4 bits (135), Expect = 2e-08
Identities = 41/134 (30%), Positives = 62/134 (46%), Gaps = 10/134 (7%)
Query: 49 LKIKQVTAEDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVE 108
+++K + +D+G Y C A + K K C+V R+L+ R +APT N+
Sbjct: 627 MELKNASLQDQGDYVCLAQD--RKTKKRHCVV----RQLTVLER-VAPTITGNLENQTTS 679
Query: 109 EGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYR 168
GE++ C GNP P W KD + + I +K+ R L I V ED G+Y
Sbjct: 680 IGESIEVSCTASGNPPPQIMWFKDNETLVEDSGIVLKDGN---RNLTIRRVRKEDEGLYT 736
Query: 169 ITVENELGRAEASA 182
+ LG A+ A
Sbjct: 737 CQACSVLGCAKVEA 750
Score = 44.0 bits (99), Expect = 4e-04
Identities = 42/135 (31%), Positives = 57/135 (42%), Gaps = 18/135 (13%)
Query: 49 LKIKQVTAEDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVE 108
L I VT D+G YTC AS+ L K N+ V H + + G M +VE
Sbjct: 292 LTIDGVTRSDQGLYTCAASSGL-MTKKNSTFVRVHEKPFVAFGSGM---------ESLVE 341
Query: 109 E--GENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
GE V G P P W K+G I + T+K +L I EVS D G
Sbjct: 342 ATVGERVRIPAKYLGYPPPEIKWYKNG--IPLESNHTIKAG----HVLTIMEVSERDTGN 395
Query: 167 YRITVENELGRAEAS 181
Y + + N + + + S
Sbjct: 396 YTVILTNPISKEKQS 410
Score = 32.7 bits (71), Expect = 1.0
Identities = 23/80 (28%), Positives = 37/80 (46%), Gaps = 9/80 (11%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTAR-LKIKQVTAEDEGTYTC 64
G+ V + G P P+I+W+ ++ ES++ L I +V+ D G YT
Sbjct: 345 GERVRIPAKYLGYPPPEIKWY------KNGIPLESNHTIKAGHVLTIMEVSERDTGNYTV 398
Query: 65 EASNCLGKAKSN--ACLVVY 82
+N + K K + LVVY
Sbjct: 399 ILTNPISKEKQSHVVSLVVY 418
>AF035121-1|AAB88005.1| 1356|Homo sapiens KDR/flk-1 protein protein.
Length = 1356
Score = 62.5 bits (145), Expect = 1e-09
Identities = 30/76 (39%), Positives = 42/76 (55%), Gaps = 2/76 (2%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+++E C +GNP P I WF E + + D DG L I++V EDEG YTC+
Sbjct: 681 GESIEVSCTASGNPPPQIMWFKDNETLVE--DSGIVLKDGNRNLTIRRVRKEDEGLYTCQ 738
Query: 66 ASNCLGKAKSNACLVV 81
A + LG AK A ++
Sbjct: 739 ACSVLGCAKVEAFFII 754
Score = 58.4 bits (135), Expect = 2e-08
Identities = 41/134 (30%), Positives = 62/134 (46%), Gaps = 10/134 (7%)
Query: 49 LKIKQVTAEDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVE 108
+++K + +D+G Y C A + K K C+V R+L+ R +APT N+
Sbjct: 627 MELKNASLQDQGDYVCLAQD--RKTKKRHCVV----RQLTVLER-VAPTITGNLENQTTS 679
Query: 109 EGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYR 168
GE++ C GNP P W KD + + I +K+ R L I V ED G+Y
Sbjct: 680 IGESIEVSCTASGNPPPQIMWFKDNETLVEDSGIVLKDGN---RNLTIRRVRKEDEGLYT 736
Query: 169 ITVENELGRAEASA 182
+ LG A+ A
Sbjct: 737 CQACSVLGCAKVEA 750
Score = 44.0 bits (99), Expect = 4e-04
Identities = 42/135 (31%), Positives = 57/135 (42%), Gaps = 18/135 (13%)
Query: 49 LKIKQVTAEDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVE 108
L I VT D+G YTC AS+ L K N+ V H + + G M +VE
Sbjct: 292 LTIDGVTRSDQGLYTCAASSGL-MTKKNSTFVRVHEKPFVAFGSGM---------ESLVE 341
Query: 109 E--GENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
GE V G P P W K+G I + T+K +L I EVS D G
Sbjct: 342 ATVGERVRIPAKYLGYPPPEIKWYKNG--IPLESNHTIKAG----HVLTIMEVSERDTGN 395
Query: 167 YRITVENELGRAEAS 181
Y + + N + + + S
Sbjct: 396 YTVILTNPISKEKQS 410
Score = 32.7 bits (71), Expect = 1.0
Identities = 23/80 (28%), Positives = 37/80 (46%), Gaps = 9/80 (11%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTAR-LKIKQVTAEDEGTYTC 64
G+ V + G P P+I+W+ ++ ES++ L I +V+ D G YT
Sbjct: 345 GERVRIPAKYLGYPPPEIKWY------KNGIPLESNHTIKAGHVLTIMEVSERDTGNYTV 398
Query: 65 EASNCLGKAKSN--ACLVVY 82
+N + K K + LVVY
Sbjct: 399 ILTNPISKEKQSHVVSLVVY 418
>AB209901-1|BAD93138.1| 1451|Homo sapiens kinase insert domain
receptor (a type III receptor tyrosine kinase) variant
protein.
Length = 1451
Score = 62.5 bits (145), Expect = 1e-09
Identities = 30/76 (39%), Positives = 42/76 (55%), Gaps = 2/76 (2%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+++E C +GNP P I WF E + + D DG L I++V EDEG YTC+
Sbjct: 776 GESIEVSCTASGNPPPQIMWFKDNETLVE--DSGIVLKDGNRNLTIRRVRKEDEGLYTCQ 833
Query: 66 ASNCLGKAKSNACLVV 81
A + LG AK A ++
Sbjct: 834 ACSVLGCAKVEAFFII 849
Score = 58.4 bits (135), Expect = 2e-08
Identities = 41/134 (30%), Positives = 62/134 (46%), Gaps = 10/134 (7%)
Query: 49 LKIKQVTAEDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVE 108
+++K + +D+G Y C A + K K C+V R+L+ R +APT N+
Sbjct: 722 MELKNASLQDQGDYVCLAQD--RKTKKRHCVV----RQLTVLER-VAPTITGNLENQTTS 774
Query: 109 EGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYR 168
GE++ C GNP P W KD + + I +K+ R L I V ED G+Y
Sbjct: 775 IGESIEVSCTASGNPPPQIMWFKDNETLVEDSGIVLKDGN---RNLTIRRVRKEDEGLYT 831
Query: 169 ITVENELGRAEASA 182
+ LG A+ A
Sbjct: 832 CQACSVLGCAKVEA 845
Score = 43.6 bits (98), Expect = 6e-04
Identities = 41/135 (30%), Positives = 57/135 (42%), Gaps = 18/135 (13%)
Query: 49 LKIKQVTAEDEGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVE 108
L I +T D+G YTC AS+ L K N+ V H + + G M +VE
Sbjct: 387 LTIDGITRSDQGLYTCAASSGL-MTKKNSTFVRVHEKPFVAFGSGM---------ESLVE 436
Query: 109 E--GENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
GE V G P P W K+G I + T+K +L I EVS D G
Sbjct: 437 ATVGERVRIPAKYLGYPPPEIKWYKNG--IPLESNHTIKAG----HVLTIMEVSERDTGN 490
Query: 167 YRITVENELGRAEAS 181
Y + + N + + + S
Sbjct: 491 YTVILTNPISKEKQS 505
Score = 32.7 bits (71), Expect = 1.0
Identities = 23/80 (28%), Positives = 37/80 (46%), Gaps = 9/80 (11%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTAR-LKIKQVTAEDEGTYTC 64
G+ V + G P P+I+W+ ++ ES++ L I +V+ D G YT
Sbjct: 440 GERVRIPAKYLGYPPPEIKWY------KNGIPLESNHTIKAGHVLTIMEVSERDTGNYTV 493
Query: 65 EASNCLGKAKSN--ACLVVY 82
+N + K K + LVVY
Sbjct: 494 ILTNPISKEKQSHVVSLVVY 513
>AB209631-1|BAD92868.1| 1034|Homo sapiens Fibroblast growth factor
receptor 4 variant protein.
Length = 1034
Score = 62.5 bits (145), Expect = 1e-09
Identities = 58/199 (29%), Positives = 79/199 (39%), Gaps = 29/199 (14%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLK-------IKQVTAED 58
G+TV+F C GNP P IRW ++D F G RL+ ++ V D
Sbjct: 280 GNTVKFRCPAAGNPTPTIRW------LKDGQAFHGENRIGGIRLRHQHWSLVMESVVPSD 333
Query: 59 EGTYTCEASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCA 118
GTYTC N +G + N L V SP R + P N G +V C
Sbjct: 334 RGTYTCLVENAVGSIRYNYLLDVLE----RSPHRPILQA--GLPANTTAVVGSDVELLCK 387
Query: 119 VKGNPSPWASWDK----DGSII----TPSARI--TVKEKEEIMRILEIDEVSIEDVGIYR 168
V + P W K +GS P ++ T + +L + VS ED G Y
Sbjct: 388 VYSDAQPHIQWLKHIVINGSSFGADGFPYVQVLKTADINSSEVEVLYLRNVSAEDAGEYT 447
Query: 169 ITVENELGRAEASARLEVI 187
N +G + SA L V+
Sbjct: 448 CLAGNSIGLSYQSAWLTVL 466
Score = 46.4 bits (105), Expect = 8e-05
Identities = 28/84 (33%), Positives = 36/84 (42%)
Query: 107 VEEGENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGI 166
V G V F+C GNP+P W KDG RI L ++ V D G
Sbjct: 277 VPAGNTVKFRCPAAGNPTPTIRWLKDGQAFHGENRIGGIRLRHQHWSLVMESVVPSDRGT 336
Query: 167 YRITVENELGRAEASARLEVITRS 190
Y VEN +G + L+V+ RS
Sbjct: 337 YTCLVENAVGSIRYNYLLDVLERS 360
>BC115736-1|AAI15737.1| 1192|Homo sapiens NRCAM protein protein.
Length = 1192
Score = 62.1 bits (144), Expect = 1e-09
Identities = 53/178 (29%), Positives = 78/178 (43%), Gaps = 20/178 (11%)
Query: 12 ECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCEASNCLG 71
+C G+P P I WF A+ D +++GT + + Q + GTYTC A N LG
Sbjct: 456 DCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQ--KDSTGTYTCVARNKLG 513
Query: 72 KAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNP--SPWASW 129
AK+ L + + A P VV+ G V+F+C VK + S W
Sbjct: 514 MAKNEVHLEI-----------KDATWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLW 562
Query: 130 DKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLEVI 187
KD + R TV +K+ ++ + +VS +D G Y L ASA L V+
Sbjct: 563 LKDNRELPSDERFTV-DKDHLV----VADVSDDDSGTYTCVANTTLDSVSASAVLSVV 615
Score = 56.4 bits (130), Expect = 7e-08
Identities = 51/182 (28%), Positives = 74/182 (40%), Gaps = 16/182 (8%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G+ + EC G P P I W ++ + Y + L+I V+ D G Y C
Sbjct: 266 GNVLSLECIAEGLPTPIIYWAKEDGML---PKNRTVYKNFEKTLQIIHVSEADSGNYQCI 322
Query: 66 ASNCLGKAKSNACLVVYHTRRLSSPGRQMAPTFYTYPFNKVVEEGENVTFKCAVKGNPSP 125
A N LG ++HT S + AP + T P N V+ GE+ T C GNP P
Sbjct: 323 AKNALG--------AIHHT---ISVRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKP 371
Query: 126 WASWDKDGSIITPSARITVKEKEEIMRILEIDEVSIEDVGIYRITVENELGRAEASARLE 185
SW +G + A K + I+ V +Y+ NE G A+A +
Sbjct: 372 RISWLTNG-VPIEIAPDDPSRKIDGDTII-FSNVQERSSAVYQCNASNEYGYLLANAFVN 429
Query: 186 VI 187
V+
Sbjct: 430 VL 431
Score = 41.9 bits (94), Expect = 0.002
Identities = 24/80 (30%), Positives = 39/80 (48%), Gaps = 3/80 (3%)
Query: 102 PFNKVVEEGENVTFKCAVKGNPSPWASWDKDGS--IITPSARITVKEKEEIMRILEIDEV 159
P + +++ EN+ +C KG P P SW ++G+ I +T+K + I + E
Sbjct: 53 PKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEG 112
Query: 160 SIEDV-GIYRITVENELGRA 178
E G+Y+ T NE G A
Sbjct: 113 KAETYEGVYQCTARNERGAA 132
Score = 40.7 bits (91), Expect = 0.004
Identities = 26/88 (29%), Positives = 43/88 (48%), Gaps = 7/88 (7%)
Query: 92 RQMAPTFYTYPFNKVVEE---GENVTFKCAVKGNPSPWASWDKDGSIITPSARITVKEKE 148
R+ PTF T N +E G ++ +C +G P+P W K+ ++ P R K E
Sbjct: 245 RERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGML-PKNRTVYKNFE 303
Query: 149 EIMRILEIDEVSIEDVGIYRITVENELG 176
+ ++I+ + E D G Y+ +N LG
Sbjct: 304 KTLQIIHVSEA---DSGNYQCIAKNALG 328
Score = 30.3 bits (65), Expect = 5.5
Identities = 23/78 (29%), Positives = 31/78 (39%), Gaps = 4/78 (5%)
Query: 7 DTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVT---AED-EGTY 62
+ + +C+ G P P W D + GT L I ++ AE EG Y
Sbjct: 62 ENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVY 121
Query: 63 TCEASNCLGKAKSNACLV 80
C A N G A SN +V
Sbjct: 122 QCTARNERGAAVSNNIVV 139
Score = 30.3 bits (65), Expect = 5.5
Identities = 21/76 (27%), Positives = 33/76 (43%), Gaps = 2/76 (2%)
Query: 6 GDTVEFECQVTGNPDPDIRWFHYAEVIRDCADFESSYDDGTARLKIKQVTAEDEGTYTCE 65
G V FEC+V + + + +D + D L + V+ +D GTYTC
Sbjct: 541 GSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKD--HLVVADVSDDDSGTYTCV 598
Query: 66 ASNCLGKAKSNACLVV 81
A+ L ++A L V
Sbjct: 599 ANTTLDSVSASAVLSV 614
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.317 0.133 0.404
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 35,537,518
Number of Sequences: 224733
Number of extensions: 1535758
Number of successful extensions: 33350
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 898
Number of HSP's successfully gapped in prelim test: 465
Number of HSP's that attempted gapping in prelim test: 23164
Number of HSP's gapped (non-prelim): 6152
length of query: 220
length of database: 73,234,838
effective HSP length: 87
effective length of query: 133
effective length of database: 53,683,067
effective search space: 7139847911
effective search space used: 7139847911
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.6 bits)
S2: 63 (29.5 bits)
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